bluuebunny/crossref_metadata_2025_split huggingface dataset:
AN INTRODUCTION TO THE MUSIC OF HELEN GRIME
Authors: Carey Christian 
Published: July 2019

AbstractThis article examines the music of composer Helen Grime. It discusses her use of melodic and harmonic materials derived from a Bothy Ballad in Two Eardley Pictures. It analyzes the frequent use of interpenetration and stratification in her music, and the morphing of motivic material via a number of transformations in her Violin Concerto. Finally, the article discusses the narrative quality found in Grime's Piano Concerto.
Fractional Arithmetic in the Tabula Alimentaria of Veleia
Authors: Stewart Charles 
Published: July 2019

AbstractThe Tabula Alimentaria of Veleia records the details of two second-century a.d. imperial alimentary schemes at the northern Italian town of Veleia, providing a rare insight into the workings of these schemes. Imperial loans are made to local landowners in exchange for pledges of specified property. Interest paid by landowners is used to fund cash subsidies for the upbringing of selected local children. In the early twentieth century, the French scholar Félix de Pachtere came close to demonstrating a consistent arithmetical relationship between a landowner's declared property value and the loan received. However, anomalies remained. This article proposes a revised formula which establishes a precise and consistent linkage between loan amounts and property declarations. Based on this arithmetical dataset, the paper proposes some hypotheses about how these fractional computations might have been performed in second-century Rome.
A Hierarchical Safety Control Strategy for Exoskeleton Robot Based on Maximum Correntropy Kalman Filter and Bounding Box
Authors: Mo Yang , Song Zhenzi , Li Hui , Jiang Zhihong 
Published: July 2019

SummaryExoskeleton robots have been widely used in many fields at present. When wearing the exoskeleton to operate, the wearer may be unconscious of the position of exoskeleton or affected by the surrounding environment, causing collision between two arms of exoskeleton or between arms and environment. The collision may result in the exoskeleton destroyed or even the wearer injured. This paper proposes a hierarchical safety control strategy for exoskeleton robots based on maximum correntropy Kalman filter and bounding box to ensure safe operation. Accurate joint angle prediction can be obtained by filtering out non-Gaussian impulsive noise using maximum correntropy criterion as evaluation criterion. Relative position relationship of the arms can be derived based on bounding box to realize hierarchical safe control. Enough experiments have been carried out, and the results validated the feasibility of the proposed method.
Proof of the Brown–Erdős–Sós conjecture in groups
Authors: NENADOV RAJKO , SUDAKOV BENNY , TYOMKYN MYKHAYLO 
Published: July 2019

AbstractThe conjecture of Brown, Erdős and Sós from 1973 states that, for any k ≥ 3, if a 3-uniform hypergraph H with n vertices does not contain a set of k +3 vertices spanning at least k edges then it has o(n2) edges. The case k = 3 of this conjecture is the celebrated (6, 3)-theorem of Ruzsa and Szemerédi which implies Roth’s theorem on 3-term arithmetic progressions in dense sets of integers. Solymosi observed that, in order to prove the conjecture, one can assume that H consists of triples (a, b, ab) of some finite quasigroup Γ. Since this problem remains open for all k ≥ 4, he further proposed to study triple systems coming from finite groups. In this case he proved that the conjecture holds also for k = 4. Here we completely resolve the Brown–Erdős–Sós conjecture for all finite groups and values of k. Moreover, we prove that the hypergraphs coming from groups contain sets of size $\Theta (\sqrt k )$ which span k edges. This is best possible and goes far beyond the conjecture.
Usutu virus: A new threat?
Authors: Clé M. , Beck C. , Salinas S. , Lecollinet S. , Gutierrez S. , Van de Perre P. , Baldet T. , Foulongne V. , Simonin Y. 
Published: July 2019

AbstractUsutu virus (USUV) is an emerging arbovirus that was first isolated in South Africa in 1959. ThisFlavivirusis maintained in the environment through a typical enzootic cycle involving mosquitoes and birds. USUV has spread to a large part of the European continent over the two decades mainly leading to substantial avian mortalities with a significant recrudescence of bird infections recorded throughout Europe within the few last years. USUV infection in humans is considered to be most often asymptomatic or to cause mild clinical signs. Nonetheless, a few cases of neurological complications such as encephalitis or meningoencephalitis have been reported. USUV and West Nile virus (WNV) share many features, like a close phylogenetic relatedness and a similar ecology, with co-circulation frequently observed in nature. However, USUV has been much less studied and in-depth comparisons of the biology of these viruses are yet rare. In this review, we discuss the main body of knowledge regarding USUV and compare it with the literature on WNV, addressing in particular virological and clinical aspects, and pointing data gaps.
Variability and stability in early language acquisition: Comparing monolingual and bilingual infants' speech perception and word recognition
Authors: Höhle Barbara , Bijeljac-Babic Ranka , Nazzi Thierry 
Published: July 2019

AbstractMany human infants grow up learning more than one language simultaneously but only recently has research started to study early language acquisition in this population more systematically. The paper gives an overview on findings on early language acquisition in bilingual infants during the first two years of life and compares these findings to current knowledge on early language acquisition in monolingual infants. Given the state of the research, the overview focuses on research on phonological and early lexical development in the first two years of life. We will show that the developmental trajectory of early language acquisition in these areas is very similar in mono- and bilingual infants suggesting that these early steps into language are guided by mechanisms that are rather robust against the differences in the conditions of language exposure that mono- and bilingual infants typically experience.
Energetic Electron Precipitation Occurrence Rates Determined Using the Syowa East SuperDARN Radar
Authors: Bland Emma C. , Partamies Noora , Heino Erkka , Yukimatu Akira Sessai , Miyaoka Hiroshi 
Published: July 2019

AbstractWe demonstrate that the Super Dual Auroral Radar Network (SuperDARN) radar at Syowa station, Antarctica, can be used to detect high frequency radio wave attenuation in the D region ionosphere during energetic electron precipitation (EEP) events. EEP‐related attenuation is identified in the radar data as a sudden reduction in the backscatter power and background noise parameters. We focus initially on EEP associated with pulsating aurora and use images from a colocated all‐sky camera as a validation data set for the radar‐based EEP event detection method. Our results show that high‐frequency attenuation that commences during periods of optical pulsating aurora typically continues for 2–4 hr after the camera stops imaging at dawn. We then use the radar data to determine EEP occurrence rates as a function of magnetic local time (MLT) using a database of 555 events detected in 2011. EEP occurrence rates are highest in the early morning sector and lowest at around 15:00–18:00 MLT. The postmidnight and morning sector occurrence rates exhibit significant seasonal variations, reaching approximately 50% in the winter and 15% in the summer, whereas no seasonal variations were observed in other MLT sectors. The mean event lifetime determined from the radar data was 2.25 hr, and 10% of events had lifetimes exceeding 5 hr.
Concurrent Jovian S‐Burst Beaming as Observed From LWA1, NDA, and Ukrainian Radio Telescopes
Authors: Imai Masafumi , Lecacheux Alain , Clarke Tracy E. , Higgins Charles A. , Panchenko Mykhaylo , Zakharenko Vyacheslav V. , Brazhenko Anatolii I. , Frantsuzenko Anatolii V. , Ivantyshin Oleg N. , Konovalenko Alexandr A. , Koshovyy Volodymyr V. 
Published: July 2019

AbstractThis paper describes the statistical property of Jupiter's millisecond burst (S‐burst) beaming for Io‐related decametric (Io‐DAM) sources from a ground‐based radio telescope network. To do so, we performed simultaneous observations of Jovian Io‐DAM S‐bursts from 15 January through 4 May 2016 for a total of nine events using several radio telescopes. These radio telescopes include the Long Wavelength Array station One (LWA1) in the United States, Nançay Decameter Array (NDA) in France, and three large radio telescopes (UTR2, URAN2, and URAN3) in Ukraine. We conducted a cross‐correlation analysis of the S‐burst spectrograms in a frequency range of 10.5 to 33 MHz over effective baselines of up to 8,950 km. We found that the beaming of the S‐bursts is formed on the flashlight‐like structure within an east‐west beam width of 2.75" for Io‐A/C, 2.63" for Io‐A', and 2.75" for Io‐B/D. In parallel, the flashlight‐like beam was completely filled because the results from all usable pairs of telescopes supported this model. Hence, these beam widths directly correspond to the minimum cone thickness where a radio source emanates over large solid angles from the same direction of Jupiter, as opposed to a localized radio source emitting over small solid angles along active magnetic flux tubes that are tied to Io's orbital motion in Jupiter's rotation frame (beacon‐like structure). Additionally, this cross‐correlation technique shows a practical benefit of producing statistical profiles of S‐bursts.
Effect of Fault Roughness on Aftershock Distribution: Plastic Off‐Fault Material Properties
Authors: Aslam Khurram S. , Daub Eric G. 
Published: July 2019

AbstractWe perform spontaneous earthquake rupture simulations on rough strike‐slip faults with off‐fault plastic material properties. We examine the off‐fault stress change and coseismic damage pattern resulting from dynamic fault slip. We use the stress output from each simulation to calculate the Coulomb failure function (CFF). We calculate the CFF values on the extensional and compressional side of the fault using parallel receiver fault orientations. We also calculate the CFF values on the extensional side of the fault using variable receiver fault orientations determined using the angle at which plastic shear strain is maximum. We calculate the probability density function for the CFF values across the fault as a function of distance. We observe a similar overall trend of the CFF values with distance for the extensional and compressional sides—our simulations show a broad range of values in the near‐fault region, while a narrow range of values occurs further from the fault. In the near‐fault region, we observe many more positive CFF change zones using variable receiver fault orientations than using parallel orientations. We calculate the areas and amplitudes of these positive CFF zones as a function of distance away from the fault. Our comparison of CFF amplitudes as a function of rupture area suggests that the spatial aftershock distribution surrounding a fault is controlled by both stress heterogeneity and the coseismic damage zone complexity. The calculations of rupture areas using our model are consistent with ruptured areas of observed aftershocks in California.
A Method of Estimating Equatorial Plasma Vertical Drift Velocity and Its Evaluation Using C/NOFS Observations
Authors: Marew H. , Nigussie M. , Hui D. , Damitie B. 
Published: July 2019

AbstractTo understand the dynamics of the equatorial ionosphere and mitigate its effect on radio wave propagation, vertical ion drift velocity empirical models have been developed using limited ground‐based and/or space‐based observations. These models, however, have not yet been validated in detail using recent observations for sufficiently different longitudinal sectors. In this paper we have evaluated the performance of two empirical models and also propose a simplified vertical drift velocity model based on basic physics laws (i.e., Ampere's and Ohm's laws) that we call it parameterized drift velocity (PDV) model. These models have been applied to estimate the E region electric field and the associated F region E × B drift velocity using observed horizontal magnetic fields, due to equatorial electrojet current, as model driver input. Drift velocities obtained from these models are compared with the Communication/Navigation Outage Forecasting System (C/NOFS) satellite in situ vertical drift observations for different longitudinal sectors. It is found, for all longitudinal sectors considered in this study, that the vertical drift velocity obtained from a model based on physics laws has shown better agreement with C/NOFS observations as compared to the outputs of other empirical models. Moreover, it is shown that the Anderson empirical model performs better than the International Reference Ionosphere model.
Coseismic Groundwater Drawdown Along Crustal Ruptures During the 2016 Mw 7.0 Kumamoto Earthquake
Authors: Hosono T. , Yamada C. , Shibata T. , Tawara Y. , Wang C.‐Y. , Manga M. , Rahman A. T. M. S. , Shimada J. 
Published: July 2019

AbstractGroundwater‐level changes after earthquakes provide insight into changes in hydrogeological properties such as permeability and pore pressure. Quantifying such changes, both their location and magnitude, is usually hindered by limited data. Using extensive high‐resolution water‐level monitoring records, we provide direct evidence of significant groundwater drawdown (4.74‐m maximum) over a 160‐km2 area along crustal ruptures after the Mw 7.0, 2016, Kumamoto earthquake. Approximately 106 m3 of water disappeared within 35 min after the main shock. The loss of water was not caused by static‐strain driven pore‐pressure decrease nor by releasing of water through structural pathways, but most likely by water transfer downwards through open cracks. Such changes may impact the security of water resources, the safety of underground waste repositories, and contaminant transport in seismically active areas.
Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection
Authors: Wang Nan , Yang Xiaofan , Sun Jiandong , Sun Zhixiao , Ma Qiyun , Wang Zhengxia , Chen Zhongqi , Wang Zibin , Hu Fan , Wang Huijuan , Zhou Linfu , Zhang Mingshun , Xu Juan 
Published: July 2019

AbstractPulmonary edema is a fatal complication of EV71-associated hand, foot, and mouth disease (HFMD). The pathogenesis of EV71-induced pulmonary edema remains largely unclear. In this study, we aimed to explore the roles of the capsid protein VP1 in the occurrence of EV71-induced pulmonary edema. The intranasal inoculation of recombinant VP1 protein caused lung inflammation with an elevation of inflammatory cytokines and neutrophils infiltration. Moreover, neutrophil extracellular traps (NETs) were observed in the lung parenchyma of the mice treated with VP1. VP1 directly induced the formation of NETs, which depended on PAD4. VP1 also damaged the lung barrier via the reduction of the tight junction protein occludin. Moreover, the EV71 attachment receptor vimentin was increased upon VP1 administration. In contrast, NETs decreased vimentin levels, suggesting a novel role for NETs in viral immune defense. These results evidenced a direct role of VP1 in EV71-induced pulmonary edema and demonstrated that NETs may be both harmful and beneficial in EV71 infection.
Development of functional dendrisomes based on a single molecule of polyesterbenzylether dendrimer and their application in cancer stem cell therapy
Authors: Mu Li-Min , Liu Lei , Liu Rui , Duan Jia-Lun , Ma Shuang , Li Xue-Qi , Cui Yi-Nuo , Su Zhan-Bo , Zhang Xiao , Hu Jian-Xing , Xie Ying , Zheng Ying , Lu Wan-Liang 
Published: July 2019

AbstractThe differentiation therapy of breast cancer stem cells (CSCs) represents a significant strategy to treat cancer, but inefficient delivery to CSCs hinders the efficacy of differentiation agents. In this work, we report a type of functional dendrisomes constructed by the synthesized amphiphilic dendrimers, which enhance cellular uptake by breast CSCs, differentiate breast CSCs by carrying all-trans retinoic acid (ATRA), and increase the anticancer efficacy by carrying ATRA and docetaxel (DTX) in vitro and in breast cancer-bearing mice. The study further reveals the mechanism of cellular uptake by breast CSCs and uncovers the differentiation mechanism by analyzing relevant signal molecules, transcription factors, and cell cycle-associated signaling pathways during differentiation therapy in breast CSCs. Hence, this study offers a novel type of functional dendrisomes for differentiation therapy of breast CSCs and has significant clinical implications.
Using cell sheets to regenerate mouse submandibular glands
Authors: Nam Kihoon , Kim Kyungsook , Dean Spencer M. , Brown Callie T. , Davis Ryan S. , Okano Teruo , Baker Olga J. 
Published: July 2019

AbstractTemperature-responsive polymer grafted tissue culture dishes release cells as confluent living sheets in response to small changes in temperature, with recovered cell sheets retaining cell–cell communications, functional extracellular matrices and tissue-like behaviors. These features promote tissue regeneration and improve transplantation efficacy in various tissues including cartilage, heart, kidney, liver, endometrium, cornea, middle ear, periodontium, and esophageal living sheet transplants. However, the functional effects of cell sheets for salivary gland regeneration to treat hyposalivation have not yet been studied. Thus, the present study aims to both establish the viability of thermoresponsive cell sheets for use in salivary glands and then explore the delivery option (i.e., single vs. multiple layers) that would result in the most complete tissue growth in terms of cell differentiation and recovered tissue integrity. Results indicate that single cell sheets form polarized structures that maintain cell–cell junctions and secretory granules in vitro while layering of two-single cell sheets forms a glandular-like pattern in vitro. Moreover, double layer cell sheets enhance tissue formation, cell differentiation and saliva secretion in vivo. In contrast, single cell sheets demonstrated only modest gains relative to the robust growth seen with the double layer variety. Together, these data verify the utility of thermoresponsive cell sheets for use in salivary glands and indicates the double layer form to provide the best option in terms of cell differentiation and recovered tissue integrity, thereby offering a potential new therapeutic strategy for treating hyposalivation.
A draft genome for Spatholobus suberectus
Authors: Qin Shuangshuang , Wu Lingqing , Wei Kunhua , Liang Ying , Song Zhijun , Zhou Xiaolei , Wang Shuo , Li Mingjie , Wu Qinghua , Zhang Kaijian , Hui Yuanyuan , Wang Shuying , Miao Jianhua , Zhang Zhongyi 
Published: July 2019

AbstractSpatholobus suberectus Dunn(S.suberectus), which belongs to the Leguminosae, is an important medicinal plant in China. Owing to its long growth cycle and increased use in human medicine, wild resources ofS.suberectushave decreased rapidly and may be on the verge of extinction.De novoassembly of the wholeS.suberectusgenome provides us a critical potential resource towards biosynthesis of the main bioactive components and seed development regulation mechanism of this plant. Utilizing several sequencing technologies such as Illumina HiSeq X Ten, single-molecule real-time sequencing, 10x Genomics, as well as new assembly techniques such as FALCON and chromatin interaction mapping (Hi-C), we assembled a chromosome-scale genome about 798 Mb in size. In total, 748 Mb (93.73%) of the contig sequences were anchored onto nine chromosomes with the longest scaffold being 103.57 Mb. Further annotation analyses predicted 31,634 protein-coding genes, of which 93.9% have been functionally annotated. All data generated in this study is available in public databases.
Multiple nitrogen functionalized magnetic nanoparticles as an efficient adsorbent: synthesis, kinetics, isotherm and thermodynamic studies for the removal of rhodamine B from aqueous solution
Authors: Ojemaye Mike O. , Okoh Anthony I. 
Published: July 2019

AbstractThe continuous demand for clean and affordable water needed for the survival of man is now a major challenge globally. Therefore, the treatment of wastewater generated from printing, textile and dyeing industries containing soluble dyes like rhodamine B (Rh-B) is of utmost important. This study investigates the efficiency of new multifunctionalized superparamagnetic nanoparticles (MNP-Tppy) for the removal of cationic Rh-B from aqueous solution. To afford MNP-Tppy, the surface of MNP was covalently functionalized with terpyridine ligand to enable an anionic charge on the adsorbent. The results of characterization including Brunauer-Emmett-Teller (BET) analysis, thermal gravimetric analysis (TGA), vibrating sample magnetometer (VSM), scanning electron microscope (SEM) and fourier transform infra–red spectroscopy (FTIR) indicate that this superparamagnetic nanoparticle functionalized with multiple nitrogen atoms was successfully synthesized. Adsorption experiments involving the effect of pH, time, temperature, adsorbent dose and adsorbate concentration show that the maximum adsorption of Rh-B using MNP-Tppy was observed at pH 9 and removal was observed to increase as solution pH increases. Similarly, time variation shows that adsorbate removal increases as adsorption time increases until the removal attained equilibrium at 15 min. Kinetic studies conducted among four kinetic models using the data obtained from effect of time indicate that the adsorption process can best be described by the pseudo-second order model. Isotherm studies conducted at three different temperatures revealed that Langmuir isotherm model fitted well for the equilibrium data with qm value of 113.64 mg g−1 and thermodynamic studies showed that the adsorption process involving the removal of Rh-B from aqueous solution by MNP-Tppy is spontaneous, endothermic and realistic in nature. Lastly, Reusability experiments indicate that MNP-Tppy can be regenerated and re-used.
Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis
Authors: Barrows Nicholas J. , Anglero-Rodriguez Yesseinia , Kim Byungil , Jamison Sharon F. , Le Sommer Caroline , McGee Charles E. , Pearson James L. , Dimopoulos George , Ascano Manuel , Bradrick Shelton S. , Garcia-Blanco Mariano A. 
Published: July 2019

AbstractHundreds of cellular host factors are required to support dengue virus infection, but their identity and roles are incompletely characterized. Here, we identify human host dependency factors required for efficient dengue virus-2 (DENV2) infection of human cells. We focused on two, TTC35 and TMEM111, which we previously demonstrated to be required for yellow fever virus (YFV) infection and others subsequently showed were also required by other flaviviruses. These proteins are components of the human endoplasmic reticulum membrane protein complex (EMC), which has roles in ER-associated protein biogenesis and lipid metabolism. We report that DENV, YFV and Zika virus (ZIKV) infections were strikingly inhibited, while West Nile virus infection was unchanged, in cells that lack EMC subunit 4. Furthermore, targeted depletion of EMC subunits in live mosquitoes significantly reduced DENV2 propagation in vivo. Using a novel uncoating assay, which measures interactions between host RNA-binding proteins and incoming viral RNA, we show that EMC is required at or prior to virus uncoating. Importantly, we uncovered a second and important role for the EMC. The complex is required for viral protein accumulation in a cell line harboring a ZIKV replicon, indicating that EMC participates in the complex process of viral protein biogenesis.