bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring Professionals’ Experiences in the Rehabilitation of Older Clients with Dual-Sensory Impairment
Authors: Fraser Sarah A. , Southall Kenneth E. , Wittich Walter 
Published: March 2019

RÉSUMÉEn vue de mieux comprendre et d’améliorer le processus de réadaptation des personnes âgées présentant à la fois une déficience auditive et visuelle, soit une double déficience sensorielle (DDS), cette étude s’est penchée sur les perspectives des professionnels de la santé qui œuvrent chez cette population. Treize professionnels aux parcours variés ont été interviewés en lien avec leur expérience de travail auprès de personnes âgées avec DDS. Les entrevues ont été transcrites et codées, et une analyse de contenu a été effectuée. Les participants des diverses professions ont perçu qu’ils devaient assumer les rôles additionnels suivants : (1) conseiller, (2) guide, (3) formateur ou rééducateur. Ces rôles consistaient à aider les personnes avec DDS et leurs familles présentant une dépression, des problèmes d’acceptation, des consultations répétées et des parcours complexes dans le système de santé. Selon les professionnels interviewés, ces rôles supplémentaires accroissent leur charge de travail et les confrontent à des problématiques pour lesquelles ils n’ont pas reçu de formation. Ils suggèrent l’implantation d’une formation sur les DDS pour les professionnels et les membres de la famille concernés, ainsi qu’une approche de réadaptation en équipe multidisciplinaire.
Development of aggressive-victims from childhood through adolescence: Associations with emotion dysregulation, withdrawn behaviors, moral disengagement, peer rejection, and friendships
Authors: Ettekal Idean , Ladd Gary W. 
Published: March 2019

AbstractAt multiple developmental periods spanning from middle childhood through adolescence, we investigated the development of aggressive-victims. Multiple-informant data collected across four grade levels (1, 5, 8, and 11; N = 482; 50% females) was used to perform person-centered analyses including latent profile and latent transition analyses in order to examine the co-occurring development of multiple forms (i.e., physical, verbal, and relational) of aggression and peer victimization. Results indicated that there were two distinct subgroups of aggressive-victims, one of which was more relational in form (i.e., relational aggressive-victims), and children in these two subgroups were distinguishable with respect to their individual characteristics (emotion dysregulation, withdrawn behaviors, and moral disengagement) and relational experiences (peer rejection and friendships). Furthermore, the findings elucidated the mechanisms by which developmental continuity and change (i.e., transitions) among the subgroups occurred across childhood and adolescence.
Attention bias to reward predicts behavioral problems and moderates early risk to externalizing and attention problems
Authors: Morales Santiago , Miller Natalie V. , Troller-Renfree Sonya V. , White Lauren K. , Degnan Kathryn A. , Henderson Heather A. , Fox Nathan A. 
Published: March 2019

AbstractThe current study had three goals. First, we replicated recent evidence that suggests a concurrent relation between attention bias to reward and externalizing and attention problems at age 7. Second, we extended these findings by examining the relations between attention and behavioral measures of early exuberance (3 years), early effortful control (4 years), and concurrent effortful control (7 years), as well as later behavioral problems (9 years). Third, we evaluated the role of attention to reward in the longitudinal pathways between early exuberance and early effortful control to predict externalizing and attention problems. Results revealed that attention bias to reward was associated concurrently and longitudinally with behavioral problems. Moreover, greater reward bias was concurrently associated with lower levels of parent-reported effortful control. Finally, attention bias to reward moderated the longitudinal relations between early risk factors for behavioral problems (gender, exuberance, and effortful control) and later externalizing and attention problems, such that these early risk factors were most predictive of behavioral problems for males with a large attention bias to reward. These findings suggest that attention bias to reward may act as a moderator of early risk, aiding the identification of children at the highest risk for later behavioral problems.
Allocentric Versus Egocentric Neglect in Stroke Patients: A Pilot Study Investigating the Assessment of Neglect Subtypes and Their Impacts on Functional Outcome Using Eye Tracking
Authors: Upshaw Jennifer N. , Leitner Damian W. , Rutherford Barbara J. , Miller Harry B.D. , Libben Maya R. 
Published: March 2019

AbstractObjective: Few studies have investigated the assessment and functional impact of egocentric and allocentric neglect among stroke patients. This pilot study aimed to determine (1) whether allocentric and egocentric neglect could be dissociated among a sample of stroke patients using eye tracking; (2) the specific patterns of attention associated with each subtype; and (3) the nature of the relationship between neglect subtype and functional outcome. Method: Twenty acute stroke patients were administered neuropsychological assessment batteries, a pencil-and-paper Apples Test to measure neglect subtype, and an adaptation of the Apples Test with an eye tracking measure. To test clinical discriminability, twenty age- and education-matched control participants were administered the eye tracking measure of neglect. Results: The eye tracking measure identified a greater number of individuals as having egocentric and/or allocentric neglect than the pencil-and-paper Apples Test. Classification of neglect subtype based on eye tracking performance was a significant predictor of functional outcome beyond that accounted for by the neuropsychological test performance and Apples Test neglect classification. Preliminary evidence suggests that patients with no neglect symptoms had superior functional outcomes compared with patients with neglect. Patients with combined egocentric and allocentric neglect had poorer functional outcomes than those with either subtype. Functional outcomes of patients with either allocentric or egocentric neglect did not differ significantly. The applications of our findings, to improve neglect detection, are discussed. Conclusion: Results highlight the potential clinical utility of eye tracking for the assessment and identification of neglect subtype among stroke patients to predict functional outcomes. (JINS, 2019, 25, 479–489)
Dietary patterns and abnormal glucose tolerance among Japanese: findings from the National Health and Nutrition Survey, 2012
Authors: Okada Emiko , Takahashi Kunihiko , Nakamura Koshi , Ukawa Shigekazu , Takabayashi Saeka , Nakamura Mieko , Sasaki Satoshi , Tamakoshi Akiko , Takimoto Hidemi 
Published: March 2019

AbstractObjectivePrevious studies have associated dietary patterns with diabetes risk in Western countries, but such studies among the Japanese population are scarce. The present study aimed to investigate dietary patterns associated with abnormal glucose tolerance determined by elevated glycated Hb (HbA1c) levels.DesignThe 2012 National Health and Nutrition Survey (NHNS) database was used for the cross-sectional study. Dietary patterns were analysed by factor analysis of twenty-five food items from the dietary intake survey and household-based semi-weighed dietary records. OR and 95 % CI for elevated HbA1c levels (≥6·5 %) according to dietary patterns were estimated using logistic regression models.SettingJapan.ParticipantsThe study population comprised 9550 Japanese aged ≥40 years registered in the nationwide NHNS.ResultsThree dietary patterns were identified: (i) high-bread and low-rice; (ii) high-meat and low-fish; and (iii) vegetable. The high-bread and low-rice pattern, characterised by high frequent consumption of bread, milk and dairy products, and fruits, and low rice intake, was associated with marginally decreased prevalence of elevated HbA1c levels (P
trend=0·047). The vegetable pattern, characterised by vegetables, mushrooms, soyabeans and soybean products, was significantly inversely associated with elevated HbA1c levels (4th v. 1st quartile: multivariable OR=0·68; 95 % CI 0·49, 0·95; P
trend=0·007).ConclusionsOur findings suggest that the vegetable pattern is associated with decreased prevalence of elevated HbA1c levels among Japanese.
Long‐Term Cumulative Effects of Intra‐Annual Variability of Unsteady River Discharge on the Progradation of Delta Lobes: A Modeling Perspective
Authors: Gao Weilun , Shao Dongdong , Wang Zheng Bing , Nardin William , Rajput Prateek , Yang Wei , Sun Tao , Cui Baoshan 
Published: March 2019

AbstractRivers, regardless of their scales and geographic locations, are characterized with natural and human‐induced variability in their discharges. While previous studies have established the effects of both interannual and intra‐annual variabilities of unsteady river discharge on delta morphological evolution, the long‐term cumulative effects of intra‐annual unsteadiness on the progradation of delta lobes has remained hitherto elusive. To address this issue, numerical experiments using simplified unsteady discharges were performed in Delft3D and compared with those assuming constant bank‐full discharges. A modified box model was further used to explore the effects of varying intra‐annual unsteadiness on the progradation of delta lobes at reduced computational cost. While the overall trends of the progradation and the ultimate area created were found to be similar between the unsteady discharge scenarios and their corresponding constant bank‐full discharge scenarios, the nuances of intermittent zig‐zag variation in natural delta lobe area were well reproduced by model simulations assuming unsteady river discharges. In addition, long‐term predictions suggested the potential existence of a tipping point in the area growth trajectory beyond which the delta lobe area declines during periods of low discharge. When confounding factors such as waves and variable sediment capture ratio were further taken into consideration, simulation results for unsteady river discharge scenarios exhibit significant deviations from constant bank‐full discharge scenarios. The implications of the modeling results for delta protection and restoration measures, such as the water‐sediment regulation scheme in the Yellow River and artificial channel diversions in the Mississippi River Delta, are also discussed.
Benefits of a Multiproxy Approach to Detrital Mineral Provenance Analysis: An Example from the Merrimack River, New England, USA
Authors: Gaschnig Richard M. 
Published: March 2019

AbstractThe advantages in provenance research of U‐Pb dating different detrital minerals along with simultaneously analyzing trace elements is demonstrated in a study of sand from the mouth of the Merrimack River in New England, USA. Zircon ages record episodes of magmatism in the Early Paleozoic, peaking in the Early Devonian, followed by quiescence through the remainder of the Paleozoic and additional magmatic episodes in the Jurassic and Cretaceous. Simultaneous measurement of trace elements in zircons reveals a shift from arc magmatism to crustal melting associated with terrane collision in the Early Devonian, while many Jurassic grains are clearly derived from A‐type granites. Detrital monazites and rutiles have Devonian and Permian ages. Many of the older monazites have trace element characteristics suggestive of igneous origin, while Permian monazites are clearly metamorphic and record orogenesis that is absent from the detrital zircon record. Rutile grains have trace element chemistry indicative of mostly metasedimentary source rocks, and Zr thermometry indicates growth under amphibolite facies conditions. Age offsets between monazite and rutile populations provide information about the region's cooling history. Titanite grains have trace element chemistry mostly consistent with igneous origin and U‐Pb ages lining up with minor zircon age populations in the Ordovician‐Silurian and the Middle Devonian, suggesting that these magmatic episodes produced metaluminous compositions. These results show that combining trace element fingerprinting with dating and analyzing multiple detrital mineral species provide a more complete portrait of the geologic history of the sediment source region than U‐Pb dating of zircon alone.
Initial Rifting of the Lhasa Terrane from Gondwana: Insights From the Permian (~262 Ma) Amphibole‐Rich Lithospheric Mantle‐Derived Yawa Basanitic Intrusions in Southern Tibet
Authors: Zeng Yun‐Chuan , Xu Ji‐Feng , Ducea Mihai N. , Chen Jian‐Lin , Huang Feng , Zhang Le 
Published: March 2019

AbstractThe Permian tectonic setting of the Lhasa Terrane in southern Tibet remains controversial (i.e., continental rift vs. subduction‐collision) and is crucial to palinspastic reconstructions of the eastern Tethys during the breakup of Gondwana. In this study, we present new geochronological, geochemical, and mineralogical data for the Permian (~262 Ma) Yawa intrusions in the southern Lhasa Terrane. These rocks are silica‐undersaturated and alkaline, with high TiO2 and moderate MgO, and exhibit enrichments in Th, light rare earth elements, and Nb‐Ta, and depletions in K. These chemical compositions, combined with uniform whole‐rock (87Sr/86Sr)i (0.7039–0.7044), εNd(t) (1.85–2.81), and εHf(t) (4.21–6.90) values, and zircon εHf(t) (4.53–9.97) and δ18O (5.04‰–5.76‰) values, indicate the magmas were derived by partial melting of amphibole‐rich lithospheric mantle. The magmas subsequently underwent fractionation of clinopyroxene, amphibole, and Fe‐Ti oxides. The amphibole in the lithospheric mantle likely formed as cumulates from low‐degree asthenospheric melts during incipient extension. Given that the amphibole‐rich metasomatic veins have a lower melting temperature than the surrounding peridotite, they were susceptible to melting during the early stages of thermal perturbation of the mantle. Because there is no evidence of Permian continental subsidence in the Lhasa Terrane, we suggest the Yawa intrusions were formed at the onset of lithospheric extension associated with initial rifting of the Lhasa Terrane from the Indian Plate during Gondwana breakup, which was a precursor to the opening of the Neo‐Tethys Ocean.
A Midlatitude HF Propagation Experiment Over New Mexico
Authors: Munton David , Rainwater D. , Gaussiran T. , Calfas R. , Reay M. , Schofield J. , Fleischmann A. 
Published: March 2019

AbstractWe describe a midlatitude ionospheric measurement experiment conducted 19–27 January 2014 at White Sands Missile Range, New Mexico, United States. This experiment was one of a series of experiments conducted under the IARPA high‐frequency Geo program. The objective was to develop a data set to be used by data assimilation studies focused on modeling of the bottomside of ionosphere and high‐frequency signal propagation. We outline the specific objectives of the experiment and the experimental configuration and describe the transmit sites and antenna array that allowed us to estimate angles‐of‐arrival for both O‐ and X‐mode signals. We provide a detailed example from 22 January 2014. This period shows the variations characteristic of medium‐scale traveling ionospheric disturbances. We use the data from this period to estimate the resolution of our angle‐of‐arrival measurements to be about 0.1°.
A full vectorial mapping of nanophotonic light fields
Authors: le Feber B. , Sipe J. E. , Wulf M. , Kuipers L. , Rotenberg N. 
Published: March 2019

AbstractLight is a union of electric and magnetic fields, and nowhere is the complex relationship between these fields more evident than in the near fields of nanophotonic structures. There, complicated electric and magnetic fields varying over subwavelength scales are generally present, which results in photonic phenomena such as extraordinary optical momentum, superchiral fields, and a complex spatial evolution of optical singularities. An understanding of such phenomena requires nanoscale measurements of the complete optical field vector. Although the sensitivity of near-field scanning optical microscopy to the complete electromagnetic field was recently demonstrated, a separation of different components required a priori knowledge of the sample. Here, we introduce a robust algorithm that can disentangle all six electric and magnetic field components from a single near-field measurement without any numerical modeling of the structure. As examples, we unravel the fields of two prototypical nanophotonic structures: a photonic crystal waveguide and a plasmonic nanowire. These results pave the way for new studies of complex photonic phenomena at the nanoscale and for the design of structures that optimize their optical behavior.
Bright-field holography: cross-modality deep learning enables snapshot 3D imaging with bright-field contrast using a single hologram
Authors: Wu Yichen , Luo Yilin , Chaudhari Gunvant , Rivenson Yair , Calis Ayfer , de Haan Kevin , Ozcan Aydogan 
Published: March 2019

AbstractDigital holographic microscopy enables the 3D reconstruction of volumetric samples from a single-snapshot hologram. However, unlike a conventional bright-field microscopy image, the quality of holographic reconstructions is compromised by interference fringes as a result of twin images and out-of-plane objects. Here, we demonstrate that cross-modality deep learning using a generative adversarial network (GAN) can endow holographic images of a sample volume with bright-field microscopy contrast, combining the volumetric imaging capability of holography with the speckle- and artifact-free image contrast of incoherent bright-field microscopy. We illustrate the performance of this “bright-field holography” method through the snapshot imaging of bioaerosols distributed in 3D, matching the artifact-free image contrast and axial sectioning performance of a high-NA bright-field microscope. This data-driven deep-learning-based imaging method bridges the contrast gap between coherent and incoherent imaging, and enables the snapshot 3D imaging of objects with bright-field contrast from a single hologram, benefiting from the wave-propagation framework of holography.
The influence of X chromosome variants on trait neuroticism
Authors: Luciano Michelle , Davies Gail , Summers Kim M. , Hill W. David , Hayward Caroline , Liewald David C. , Porteous David J. , Gale Catharine R. , McIntosh Andrew M. , Deary Ian J. 
Published: March 2019

AbstractAutosomal variants have successfully been associated with trait neuroticism in genome-wide analysis of adequately powered samples. But such studies have so far excluded the X chromosome from analysis. Here, we report genetic association analyses of X chromosome and XY pseudoautosomal single nucleotide polymorphisms (SNPs) and trait neuroticism using UK Biobank samples (N = 405,274). Significant association was found with neuroticism on the X chromosome for 204 markers found within three independent loci (a further 783 were suggestive). Most of the lead neuroticism-related X chromosome variants were located in intergenic regions (n = 397). Involvement ofHS6ST2, which has been previously associated with sociability behaviour in the dog, was supported by single SNP and gene-based tests. We found that the amino acid and nucleotide sequences are highly conserved between dogs and humans. From the suggestive X chromosome variants, there were 19 nearby genes which could be linked to gene ontology information. Molecular function was primarily related to binding and catalytic activity; notable biological processes were cellular and metabolic, and nucleic acid binding and transcription factor protein classes were most commonly involved. X-variant heritability of neuroticism was estimated at 0.22% (SE = 0.05) from a full dosage compensation model. A polygenic X-variant score created in an independent sample (maximumN≈ 7,300) did not predict significant variance in neuroticism, psychological distress, or depressive disorder. We conclude that the X chromosome harbours significant variants influencing neuroticism, and might prove important for other quantitative traits and complex disorders.
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells
Authors: Lai Tai-Yu , Chen I-Ju , Lin Ruey-Jen , Liao Guo-Shiou , Yeo Hui-Ling , Ho Ching-Liang , Wu Jen-Chine , Chang Nai-Chuan , Lee Andy Chi-Lung , Yu Alice L. 
Published: March 2019

AbstractFUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer. Herein, we investigated the roles of FUT1 and FUT2 in breast cancer. Silencing of FUT1 or FUT2 by shRNAs inhibited cell proliferation in vitro and tumorigenicity in mice. This was associated with diminished properties of cancer stem cell (CSC), including mammosphere formation and CSC marker both in vitro and in xenografts. Silencing of FUT2, but not FUT1, significantly changed the cuboidal morphology to dense clusters of small and round cells with reduced adhesion to polystyrene and extracellular matrix, including laminin, fibronectin and collagen. Silencing of FUT1 or FUT2 suppressed cell migration in wound healing assay, whereas FUT1 and FUT2 overexpression increased cell migration and invasion in vitro and metastasis of breast cancer in vivo. A decrease in mesenchymal like markers such as fibronectin, vimentin, and twist, along with increased epithelial like marker, E-cadherin, was observed upon FUT1/2 knockdown, while the opposite was noted by overexpression of FUT1 or FUT2. As expected, FUT1 or FUT2 knockdown reduced Globo H, whereas FUT1 or FUT2 overexpression showed contrary effects. Exogenous addition of Globo H-ceramide reversed the suppression of cell migration by FUT1 knockdown but not the inhibition of cell adhesion by FUT2 silencing, suggesting that at least part of the effects of FUT1/2 knockdown were mediated by Globo H. Our results imply that FUT1 and FUT2 play important roles in regulating growth, adhesion, migration and CSC properties of breast cancer, and may serve as therapeutic targets for breast cancer.
The evolution of skyrmions in Ir/Fe/Co/Pt multilayers and their topological Hall signature
Authors: Raju M. , Yagil A. , Soumyanarayanan Anjan , Tan Anthony K. C. , Almoalem A. , Ma Fusheng , Auslaender O. M. , Panagopoulos C. 
Published: March 2019

AbstractThe topological Hall effect (THE) is the Hall response to an emergent magnetic field, a manifestation of the skyrmion Berry-phase. As the magnitude of THE in magnetic multilayers is an open question, it is imperative to develop comprehensive understanding of skyrmions and other chiral textures, and their electrical fingerprint. Here, using Hall-transport and magnetic-imaging in a technologically viable multilayer film, we show that topological-Hall resistivity scales with the isolated-skyrmion density over a wide range of temperature and magnetic-field, confirming the impact of the skyrmion Berry-phase on electronic transport. While we establish qualitative agreement between the topological-Hall resistivity and the topological-charge density, our quantitative analysis shows much larger topological-Hall resistivity than the prevailing theory predicts for the observed skyrmion density. Our results are fundamental for the skyrmion-THE in multilayers, where interfacial interactions, multiband transport and non-adiabatic effects play an important role, and for skyrmion applications relying on THE.