bluuebunny/crossref_metadata_2025_split huggingface dataset:
Late-onset Pompe disease: preliminary results of enzyme replacement therapy
Authors: Smertina L. P. , Ausheva F. I. , Gryaznov A. V. , Svetlakov D. A. , Kolbasin L. N. 
Published: July 2019

Pompe disease is an orphan hereditary accumulation disease associated with a deficiency of the lysosomal enzyme alglucosidase alpha. Manifestations of the disease are associated with pathological deposition of glycogen in body tissues as a result of GAA gene mutation and subsequent reduction in the activity of the enzyme alglucosidase alpha or acid maltase. The variety of phenotypic forms and varying degrees of damage to the skeletal and respiratory muscles, cardiomyocytes and internal organs greatly complicates the diagnosis and treatment of patients with Pompe»s disease. This article describes the clinical case of late-onset Pompe disease, which was followed by a course of enzyme replacement therapy, as well as an assessment of the condition before and after treatment and preliminary results.
IMPORTANCIA DE LA VIGILANCIA EPIDEMIOLÓGICA EN EL CONTROL DE LAS INFECCIONES ASOCIADAS A LA ATENCIÓN EN SALUD
Authors: Barahona Nayide , Rodriguez Marena , De Moya Yurina 
Published: July 2019

Antecedentes: Las infecciones asociadas a la Atención en salud (IAAS) son un flagelo que azota a las instituciones prestadoras de servicio de salud a escala Mundial, se considera uno de los mayores problemas para la seguridad del paciente, afectando directamente la calidad en la prestación de servicios. Objetivo: Profundizar en los principales aspectos epidemiológicos de la IAAS, los factores de riesgo relacionados, el impacto que tiene este problema a nivel mundial y local y la importancia de un programa de vigilancia epidemiológica hospitalaria como una de las medidas para su prevención y control. Metodología: El presente documento es el resultado de una revisión bibliográfica de artículos científicos consultados en bases de datos Pubmed, Scielo, Proquest, Ovid, Google Académico, de los últimos 10 años, publicados en español y en inglés. Para la selección de la bibliografía se consideró el siguiente grupo de palabras claves: infección Asociada a la atención de la salud; infección intrahospitalaria; control de infecciones, vigilancia epidemiológica, sistema nacional de vigilancia hospitalaria. Conclusión: Con la revisión actual se evidenció que la prevalencia de IAAS se mantiene a través de los años, e incluso ha aumentado en instituciones de nivel intermedio de atención en salud, resaltando la importancia de incrementar las unidades notificadoras de IAAS y resistencia bacteriana, así como la creación de programas de vigilancia epidemiológica o Sistema Nacional de información de estos eventos de manera más eficiente, considerándose un componente clave de cualquier sistema de salud para mejorar los indicadores de la calidad en los servicios prestados en beneficio del paciente. La Vigilancia Epidemiológica es importante no solo por contribuir de manera significativa en el control y prevención de las IAAS sino para determinar los pasos a seguir en el momento de registrar y difundir debidamente, a las autoridades encargadas del análisis de dicha problemática en sus diferentes esferas de acción, apoyando de esta manera la toma de decisiones, la ejecución y evaluación de dichas enfermedades.
Relación entre el índice de masa corporal y actividad física en universitarios de la ciudad de Barranquilla en el semestre 2018-2, Universidad del Atlántico
Authors: Nieto Ortiz Dolores , Torrenegra Ariza Silvia 
Published: July 2019

Antecedentes: En el contexto colombiano, las cifras con respecto a la obesidad y el sobrepeso, suponen una situación alarmante de salud pública; según la 3ra Encuesta Nacional de Situación Nutricional para Colombia (ENSIN), más del 27% de la población adulta padece de sobrepeso, mientras que un 19% tiene obesidad.
Objetivo: Establecer la relación entre el IMC y los niveles de actividad física en una muestra de estudiantes de la Universidad del Atlántico en edades de 18 a 25 años en el semestre 2018-2 que se encontraban cursando la cátedra Deporte Formativo.
Materiales y métodos: Diseño cuantitativo, de tipo correlacional y corte transversal, aplicados a una muestra de 207 estudiantes de la Universidad del Atlántico de edades entre 18 y 25 años (M= 20,5), 52% de sexo masculino (M=20,7) y 42% de sexo femenino (M=20,3), a quienes se les tomó medidas antropométricas para determinar su índice de masa corporal, como también la aplicación del International Physical Activity Questionnaire (IPAQ). Resultados: Se evidencian diferencias considerables entre los tipos de IMC asociados a obesidad y sobrepeso con respecto al bajo peso y normal, habiendo en los primeros una mayor frecuencia hacia las categorías de actividad física sentado y caminando; entre tanto, en el bajo peso y normal se observa mayor tendencia hacia la categoría vigorosa y modera; en cuanto a la valoración por sexos en los tipos de IMC y las categorías de actividad física, no se observan diferencias estadísticas considerables. Conclusión: En la muestra se identificaron problemas importantes de malnutrición e inactividad física. De estos hallazgos surge la necesidad de intensificar las acciones por parte de los docentes de la cátedra Deporte Formativo en pos de promover estilos de vida saludable.
Sonographic assessment of fetal head deflexion using occiput: spine angle measured during first stage of labour and its role in predicting the mode of delivery among nulliparous women
Authors: Somu Keerthi , S. Sujatha B. , Hebbar Shripad , G. Shyamala , Pai Muralidhar V. 
Published: July 2019

Background: The attitude of the fetal head during labour significantly influences the progress and outcome of delivery and is mainly diagnosed by vaginal examination during labour. The aim of the study was to quantify the extent of deflexion of the fetal head by measuring the fetal occiput spine angle (OSA) through transabdominal ultrasonography in the first stage of labour and to determine whether the fetal OSA can predict the mode of delivery.Methods: We conducted a prospective observational study on 145 nulliparous uncomplicated singleton pregnant women without occiput-posterior position of the fetus during active labour. The OSA was measured as the angle between the two tangential lines to the occipital bone and the vertebral body of the first cervical spine, during active labour and monitored until delivery. Intra- and interobserver reproducibility of the OSA measurement and the correlation between the OSA and mode of delivery were also evaluated.Results: For the study population, the mean value of the OSA measured in the active phase of the first stage was 124.2±11.5⁰. The OSA measurement showed excellent intraobserver agreement (r = 0.82; 95% confidence interval [95% CI] 0.70-0.80) and fair-to-good interobserver agreement (r = 0.62; 95% CI 0.51-0.71). The mean OSA was significantly less for the group of patients who required conversion to cesarean section due to labour arrest (n=32) as compared to those who had vaginal delivery (n=113) (116.25±9.2⁰ versus 126.53±11.1⁰, P<0.01). An OSA of ≥121° was associated with vaginal delivery in 80.5% (91/113) of women, whereas 87.5% (28/32) of the women who delivered by cesarean section had an OSA <121⁰.Conclusions: Measurement of the OSA, by sonography is feasible, reproducible and an objective tool to assess the degree of fetal head deflexion during labour and to predict the mode of delivery.
A study on maternal near miss cases in Government Medical College Shivpuri, India
Authors: Jain Uma 
Published: July 2019

Background: Obstetrics near miss is an important indicator that reflects the quality of obstetrics care in a health facility. It assesses and monitors the activities aimed for prevention of maternal mortality. The aim and objective of this study was to find out the incidence, the prevalence and causes of maternal near miss due to severe obstetric complications and to identify the gapes and contextualize corrective measures to be taken in our facility.Methods: This is a retrospective study done in department of Obstetrics and Gynecology in GMC associated with DHS Shivpuri MP. The study was done during a period from 1st January 2018 to 30 April 2019.Results: In this study the hospital maternal near miss incidence ratio was 14.34%. In our study we found the most common morbidity was (30.18%) hypertensive disorder of pregnancy. These 159 near miss diagnoses were comprised of (30.18 %) cases of Hypertensive disorder of pregnancy, (27.67%) cases of major obstetric hemorrhage, (6.91) Severe systemic infection or sepsis, (4.40%) Labour related disorders. In Medical disorders very Severe Anemia, (1.88%) was most common cause of near miss. The most common cause of death was post-partum hemorrhage 37.5% and most of the patients referred from periphery in very critical condition. The median time taken to get clinical intervention among cases was 20-40 minutes after admission.Conclusions: Hemorrhage and hypertension disorders are the leading causes of MNM. Prompt diagnosis and adequate management of near miss cases can reduce mortality rates.
Application of the Theory of Planned Behavior to Predict Drug Abuse-Related Behaviors among Adolescents
Authors: Mazloomy Mahmoodabad Seyed Saeed , Sadeghi Saeedeh , Jadgal Mohammad Saeed , Yooshany Nooshin , Agh Atabay Rabee , Movahed Ehsan , Alizadeh Somayeh 
Published: July 2019

Introduction: Drug abuse is one of the important challenges in the field of mental health and adolescence health promotion. Due to the social and medical costs of drug abuse and its consequences among the youth, it is necessary to deal with this issue effectively. Therefore, in this theoretical study, the predictability of the Theory of Planned Behavior on drug abuse related behaviors was explained among adolescents.
Methods: This cross-sectional study was conducted in Chabahar City in 2015 among 300 male adolescents, recruited randomly. All data were collected using a researcher-made questionnaire with confirmed reliability and validity. The data were analyzed by independent t- test and pearson correlation.
Results: we found that 77% of the participants had no history of parental drug abuse. Furthermore, 72% of participants reported a history of using industrial drugs in their friends. The Chi-square test showed that adolescent's smoking had a significant relationship with father's education, family size, history of using industrial drugs in parents , history of using industrial drugs in friends, and the participants' business o (P˃0.000). However, the level of maternal education (P = 682) and living with parents (P = 729) had no significant relationship with the adolescents' smoking rate.
Conclusions: since knowledge and attitude had the highest correlation and predictability with industrial drug abuse among the adolescents, theory of planned behavior can be used properly and effectively to plan and implement prevention programs among the adolescents.
The Effect of Scheduling on Operating Room Utilization at an Affiliated Hospital of Shahid Sadoughi University of Medical Sciences in Yazd
Authors: Tabibi Seyed Jamaledin , Delgoshaei Bahram , Nikfard Maryam 
Published: July 2019

Introduction: Resource management and efficiency analysis assist the hospitals in controlling the expenses and optimum utilization. Operating room (OR) is one of the most critical and expensive resources in a hospital. Operating room utilization is a measure calculated as a ratio between the available time and the used actual minutes. In the current study, we aimed to measure OR utilization in Yazd Shahid Sadoughi Hospital.
Methods: This is a descriptive cross-sectional study in which all the surgeries performed in ORs of Shahid Sadoughi Hospital were investigated during a 15-day period. Data were collected from four randomly-selected rooms in the surgical unit in January 2013 using some pre-designed checklists.
Results: A total of 151 surgeries were conducted during a 53-day period in four ORs. We found that OR utilization was 68% for the Orthopedics, 61% for the Ophthalmology, 89% for the General Surgery, and 86% for the ear, nose and throat (ENT) ORs. Total adjusted utilization was 77% and raw utilization rate was 70%. Of the 19080 minutes dedicated for surgeries, 13400 minutes were spent on surgeries and 1215 minutes were used for the turn-over-time or the delay between two surgeries. Of 53 days, the ORs were used efficiently for 7 days, under-utilized for 27 days, and over-utilizedfor 19 days.
Conclusion: Data analysis showed that the Orthopedics and Ophthalmology ORs were under-utilized; whereas, the General Surgery room was over-utilized. The ENT utilization was in an appropriate range. The lowest utilization rate in a day was recorded for the Orthopedics OR (17%), while the highest rate was 158% for ENT. Further studies are recommended to measure OR utilization in a longer period of time and use the research findings to have accurate scheduling for the ORs leading to their efficiency improvement.
The assessment of Mevlana Exchange Program: The case of Morocco
Authors: Tasar Haci Huseyin 
Published: July 2019

Mevlana Exchange Program is a program that helps to exchange students and academics between the Turkish universities and foreign higher education institutes in Turkey and other countries. The aim of this study is to determine the views and recommendations of exchange students Adiyaman University, who went to Morocco within the scope of Mevlana Exchange Program. This study has been designed to be a case study which is patterned on a basis of qualitative research. Within the research, the opinions of the participants were gathered with a â€˜structured interview formâ€™ which was developed by the researcher through taking expertâ€™s opinion. The research is limited with the pieces of information that were provided by the students who went to Morocco. The vast majority of students who have gone to the country in question have expressed that they were not satisfied with the services, such as health, alimentation, sheltering and security and experienced huge problems.
Keywords: Adiyaman University, higher education, Mevlana Exchange Programme.
Self-esteem, hopelessness and communication skills in preschool teacher candidates: A mediation analysis
Authors: Uyanik Balat Gulden , Sezer Turker , Bayindir Dilan , Yilmaz Elif 
Published: July 2019

The goal of this study is to investigate the relation of self-esteem, hopelessness and communication skill; while testing self-esteem as an intermediary variable. The research, designed in survey model, has been conducted with preschool teacher candidates. The research group comprises 305 teacher candidates that volunteered for the research. According to the findings of the research, teacher candidatesâ€™ self-esteem is negatively correlated with their level of hopelessness and positively correlated with their communication skills. On the other hand, the relation between their level of hopelessness and communication skill is a negative correlation. According to the results of regression analysis, hopelessness, along with self-esteem, explain 31.6% of communication skill. Furthermore, another very important finding of the regression analysis is that teacher candidatesâ€™ self-esteem plays a complete intermediary role in the relation between their level of hopelessness and their communication skill. Implications of the findings are discussed in the light of the related literature.
Keywords: Self-esteem, hopelessness, communication skills, preschool teacher candidates
Relationships between self-efficacy beliefs, engagement and academic performance in math lessons
Authors: Ozkal Nese 
Published: July 2019

This study investigated secondary school sixth, seventh and eighth gradersâ€™ self-efficacy beliefs, engagement and disaffection in Math lessons and academic achievement in relation to learning Mathematics and Math performance. The study was conducted with the voluntary participation of 651 sixth, seventh and eighth graders attending secondary school. Research data were collected with the help of â€˜Engagement and Disaffection Scaleâ€™, â€˜Self-Efficacy sub dimensionâ€™ of â€˜Motivation Scaleâ€™ related to learning and performance and studentsâ€™ Math first semester grades. It was identified in the study that studentsâ€™ self-efficacy beliefs in learning and performance in Math significantly and positively predicted their Math achievement. Behavioural and affective disaffection in Math lessons were found to predict Math achievement negatively. It was determined in the study that studentsâ€™ self-efficacy beliefs related to learning and performance in Math significantly predicted their behavioural and affective engagement in Math positively while predicting their behavioural and affective disaffection negatively.
Keywords: Math, engagement, self-efficacy, academic achievement.
Preschool curriculum implementation in Ethiopia: The case of selected woredas preschools
Authors: Tarekegne Wudu Melese , Megersa Addisu Kumsa 
Published: July 2019

The purpose of this study was to investigate the practice of preschool curriculum implementation in selected woredas of South West Shoa Zone. For this study, descriptive survey research design was used. Data were gathered from 49 O-Class, 9 kindergartens, 192 teachers, 58 principals, 12 cluster supervisors and 4 woreda education experts. The findings of the study revealed that the objectives of the curriculum were unable to address all domains of childrenâ€™s development, the contents lack relevance to prepare children for life and learning ahead. In addition, appropriate instructional methods, materials, assessment and record keeping systems that guarantee the proper implementation of the curriculum were not employed. On the other hand, the major factors that can affect the implementation of preschool education in schools are generally related to lack of textbooks, teacherâ€™s guides, syllabuses, policy documents and manuals, and lack of uniformity on the implementation of the program.
Key words: Curriculum implementation, Ethiopia, practice, preschool.
Fait tendencies regarding disability problems within the families
Authors: Demirok Mukaddes Sakalli , Meral Karabacak Serap , Aysever Harun 
Published: July 2019

Parents of children with special needs have many duties when compared to parents of children with typical development and they face with many hardships in every stages of their lives. Parents cannot cope with hardships easily and they can fray out from emotional dimensions. This study carried out based on the idea that problems and hardships experienced by the parents of children with special needs make them to head for religion. It was aimed to determine the religious tendencies of parents of children with special needs in this research. Participants of the study consisted of 68 parents of children with special needs and â€˜Religious Tendency Scaleâ€™ was administered to the parents. The results of the study showed that parents were undecided on general religious tendency, internal and external religious tendency.
Keywords: Family, perception, religious, relational belief, special needs children.
Aesthetic perceptions of art educators in higher education level at art classes and their effect on learners
Authors: Miralay Fatma , Egitmen Ziynet 
Published: July 2019

The objective of this study is to examine the aesthetic awareness of art education academicians working in different higher education institutions of Turkish Republic of Northern Cyprus. Qualitative method and descriptive analysis were used in the study. A semi-structured interview form was created to reveal the views of academicians, and interviews were conducted to determine the levels of aesthetic competence with art education. The results of the research reveals that there is a relatively high level of aesthetic competence among the art educators who participated in the study. The participants emphasised that the theoretical structure of art classes can encourage students' creativity and aesthetic perceptions as well as awareness. In addition, the proficiency level of aesthetics may be directly related to the quality of art education curricula of the faculty. As a result, aesthetic perception levels not only help to improve students'success but also enable them to create artworks and motivate students' performance in creating artworks.
Keywords: Art, aesthetic, perception, fine arts, higher education, Cyprus.
ANALISIS IN VITRO AKTIVITAS ANTIBAKTERI DAUN SISIK NAGA (Drymoglossum pilosellaoides) TERHADAP BAKTERI Vibrio harveyi DAN Vibrio parahaemolyticus
Authors: Hamzah Azis 
Published: July 2019

Penelitian ini mengenai bioaktifitas ekstrak daun sisik naga (Drymoglossum pilosellaoides) terhadap pertumbuhan bakteri Vibrio harveyi dan Vibrio parahaemolyticus. Penelitian ini bertujuan untuk mengetahui bioaktifitas dan efektifitas antibakteri ekstrak daun sisik naga terhadap pertumbuhan bakteri V. harveyi dan V. parahaemolyticus. Pengujian daya hambat dilakukan dengan metode difusi agar menggunakan 5 variasi konsentrasi 100%, 50%, 25%, 12,5% dan 6,25% b/v pada media TSA (Tryptone Soya Agar) dan TCBS (Thiosulfate Citrate Bile Salts Sucrose) yang diinkubasi selama 2x24 jam. Digunakan pula antibiotik berupa chloramphenicol 10-1 (= 30 µg) sebagai kontrol positif, dan sebagai kontrol negatif digunakan akuades. Ekstrak daun sisik naga. mengandung flavonoid, saponin dan tanin yang bersifat antibakteri dan memiliki kemampuan mematikan bakteri uji, dengan efektifitas diameter hambatan V. harveyi 14,8 mm pada konsentrasi 100% b/v, sedangkan bakteri V. parahaemolyticus 11,8 mm pada konsentrasi 50% b/v. Efektifitas daya hambat tertinggi pada konsentrasi 50% terhadap bakteri V. parahaemolitycus yaitu sebesar 45,5%, Sedangkan pada konsentrasi 100% memiliki efektifitas daya hambat sebesar 56,3% terhadap bakteri V. harveyi.
Design Thinking as a Catalyst for Technology Start-Ups
Authors: Soyupak Ozan , Bagli Humanur 
Published: July 2019

This study is based on the projects held in a Design Thinking Graduate class in 2016-2017 and 2017-2018 Fall Semesters, in an industrial design department. Based on the hypothesis that design thinking interventions to entrepreneurship projects will help their development, graduate students were paired with technology start-ups. The aim of the project is to intervene the project development process of technology start-ups with a human centred perspective by the help of the tools of design thinking approach, develop ideas for solving existing problems, also pin out new problems that are not classified as problems by the companies yet. Following this idea, students were required to design and conduct their own process by the help of design thinking approach and related methods. The number of the projects held during the process was 34 and 4 of them will be explained in detail in this paper. This study is significant in terms of investigating how design thinking affects start-up culture as a catalyst, in which phase/s of the projects design thinking is more relevant and effective, how design thinking helps find solutions to missing and premature aspects of entrepreneurship projects.