bluuebunny/crossref_metadata_2025_split huggingface dataset:
Colonic Stool Burden a Useful Surrogate for Slow Transit Constipation as Determined by a Radiopaque Transit Study
Authors: Cangemi David J. , Flanagan Ryan , Barshop Kenneth , Kuo Braden , Staller Kyle 
Published: February 2019

OBJECTIVES:
Plain film abdominal x-ray (AXR) is frequently used in the evaluation of constipation, but studies assessing the association between stool burden on AXR and colonic transit have been limited. We sought to investigate the relationship between colonic stool burden and slow transit constipation, as determined by a radiopaque marker (ROM) transit study.

METHODS:
A retrospective cohort population was assembled, consisting of adult patients with chronic constipation who underwent testing with both a ROM study and anorectal manometry at 2 tertiary care centers over 5 years. Stool burden was graded by 2 independent observers, with colonic transit being assessed by the Hinton method.

RESULTS:
Of 361 patients, 145 (40.3%) had slow transit constipation, and women were more likely than men to have slow transit constipation (42.3% vs 26.5%, P = 0.04). The mean stool burden scores by observer 1 and observer 2 for patients with slow transit constipation were significantly higher than the mean stool burden scores for patients with normal transit constipation (8.1 ± 1.6 vs 6.9 ± 1.9, P < 0.0001; 8.5 ± 1.5 vs 5.8 ± 1.6, P < 0.0001). The Pearson correlation coefficient for the stool burden score and number of remaining ROMs was 0.31 (moderate) for observer 1 (P < 0.0001) and 0.62 (strong) for observer 2 (P < 0.0001), whereas the Pearson correlation coefficient for interrater reliability of the stool burden score was 0.58 (P < 0.0001), indicating a strong correlation. The ideal score cutoff for both observers was 7, with moderate agreement by Cohen's kappa (0.43, P < 0.0001).

CONCLUSIONS:
Stool burden assessment on AXR may be a reliable alternative ROM study in the assessment of colonic transit.
Investigation of relationship between smartphone addiction and internet addiction in working children in industry
Authors: Yayan Emriye Hilal , Dağ Yeliz Suna , Düken Mehmet Emin , Ulutaş Ayşegül 
Published: February 2019

Aim: The aim of the study was conducted to examine the relationship between smartphone addiction and internet addiction of working children in industry.Material and Method: This research was carried out with 183 children working at various work places in Diyarbakır province center between January and March 2017 as a descriptive relational. Child Information Form, Young Internet Addiction Scale and Smart Phone Dependence Scale were used in the study. The data were collected by face-to-face interview technique.Results: According to the statistical results of the study group, the average age of the students participating in the study was 14.53 ± 2.08. The average Internet and smartphone addiction scores of children whose mother were not alive (p = 0.000) or whose father (p = 0.000) were not alive and whose internet use was not supported (p = 0.000) were found to be higher. The mean scores of the groups were found to be significantly different. The mean internet and smart phone addiction scores of the children who worked well with the master at work (p = 0.000, p = 0.035) were found to be low and there was a significant difference between the groups. Children who were exposed to violence in the work environment (p=0.000) are quite high internet and smart phone addiction scores and the difference between the groups was found to be significant. It had founded that the children who use smart phone and internet for fun (p = 0.001, p = 0.002), chatting (p = 0.005) and browsing sites (p = 0.038, p = 0.001) was higher phone addiction and internet addiction scores. It was determined that there was a meaningful difference between the average scoresConclusion: Working children showed high internet and smart phone addiction behaviors, this resulted from originated family and social environment.
The effects of gender on problem solving skills of nursing students in Turkey: a meta-analysis study<p>Türkiye’deki hemşirelik öğrencilerinin problem çözme düzeylerine cinsiyetin etkisi: Bir meta analiz çalışması
Authors: Kantek Filiz , Yeşilbaş Hande 
Published: February 2019

The aim of this study is to the effects of gender on problem solving skills of nursing student using meta-analysis method in Turkey. Online databases were scanned to reach studies to be included in the survey. In scanning 'problem solving', 'student nurse', 'Turkey', 'problem solving skill' keywords were used in Turkish and English. Six studies that meet the criteria were included in the study. The CMA statistical program was used in the analysis of the data. Q and I2 values to test heterogeneity and, Orwin's Fail-Safe N and Tau coefficients to publication bias of the included studies were calculated. A random effects model was used to examine the effect size. The six studies' total sample size was 2079 nursing students, 436 male and 1643 female. Heterogeneity and publication bias test showed that studies were heterogeneous and there was not publication bias. The mean effect size on gender problem solving was calculated as 0.079. In conclusion, it was identified that the effect of gender on problem solving level of student nurses was insignificant for women. For future studies, it will be useful to conduct meta-analysis studies on the different factors that affect the problem solving level of student nurses.Extended English summary is in the end of Full Text PDF (TURKISH) file. ÖzetBu çalışmanın amacı, meta analiz yöntemi kullanarak Türkiye’deki hemşirelik öğrencilerinin problem çözme beceri düzeylerine cinsiyetin etkisini belirlemektir. Online very tabanları kullanılarak araştırmaya dahil edilecek çalışmalara ulaşıldı. Taramada ‘problem çözme-problem solving’, ‘öğrenci hemşire- student nurse’’, ‘Türkiye-Turkey’, ‘problem çözme becerisi- problem-solving skill’ anahtar kelimeleri kullanıldı. Dahil edilme kriterlerine uygun olan altı çalışma araştırmaya dahil edildi. CMA istatistik programını kullanarak veri analizi sağlandı. Meta analize dahil edilen çalışmaların heterojenliğini ve yayın yanlılığını test etmek için Q ve I2 değerleri, Orwin’s Fail-Safe N ve Tau katsayısı hesaplandı. Etki büyüklüğünün incelenmesinde rastgele etkiler modeli kullanıldı. Araştırmaya dahil edilen altı çalışmanın toplam örneklem büyüklüğü 2079 hemşirelik öğrencisi olup, 436’sı erkek ve 1643’ü kadındı. Heterojenlik ve yayın yanlılığı testi çalışmaların heterojen olduğunu ve yayın yanlılığının olmadığını gösterdi. Cinsiyetin problem çözme üzerine ortalama etki büyüklüğü 0.079 olarak hesaplandı. Sonuç olarak öğrenci hemşirelerin problem çözme düzeyine cinsiyetin etkisinin kadınlar lehine önemsiz düzeyde olduğu belirlendi. Gelecek çalışmalar için öğrenci hemşirelerin problem çözme düzeyini etkileyen farklı faktörlere ilişkin meta analiz çalışmalarının yapılması yararlı olacaktır.
Co je škola?
Authors: Dlouhá Jana , Holec Jakub 
Published: February 2019

Recenze publikace Tajemství školy za školou. Proč učení venku v přírodě zlepšuje vzdělávací výsledky, motivaci a chování žáků
Autor: Petr Daniš (2018). Vydalo Ministerstvo životního prostředí, ISBN 978-80-7212-631-6. Dostupné online: https://ucimesevenku.cz/wp-content/uploads/2018/11/Tajemstvi_skoly_za_skolou_UCIME-SE-VENKU.pdf
Occurrence of Red Kites Milvus milvus in Serbia based on birds tracked by telemetry devices
Authors: Literák Ivan , Raab Rainer , Vyhnal Stanislav , Spakovszky Péter , Steindl Jochen 
Published: February 2019

Abstract
A total of 13 Red Kites Milvus milvus fitted with GPS/GSM telemetry loggers in central Europe were tracked in Serbia from 10 July 2014 until 31 March 2018. These birds remained in Serbia for 138 days (counted as number of one bird/one day stays). Red Kites occurred mostly in the Vojvodina Province (NW Serbia). They were registered most often in April and October, which corresponded to their spring and autumn migrations. It is possible that Red Kites occur in Serbia more often than formerly, and this could in future result in this threatened European raptor’s more frequently wintering and breeding within the country.
Gull attacks on migrating birds at Ada Island (S Montenegro)
Authors: Bordjan Dejan , Kljun Ivan 
Published: February 2019

Abstract
Migration poses a high risk to birds. Crossing of large bodies of water is especially demanding for land birds. One of the dangers faced by migrants are opportunistic predators like gulls. Most gulls Laridae are generalist predators with omnivorous diets. Attacking on migrating birds was investigated during ground observations of bird migration at Ada Island (S Montenegro) between 17 Mar and 10 Apr 2015. We recorded 20 attacks on 22 individuals of six species and on one unidentified passerine. In four instances gulls attacked birds of prey, in two Hoopoe Upupa epops and in 16 passerines. Except for two cases when small flocks of two birds were attacked, gulls attacked individuals migrating singly. Considering our data around one percent of passerines migrating during the day across the southern Adriatic Sea can expect to be attacked by gulls. This percentage can be as high as 9.5% for passerines migrating singly.
Valorization of waste foods using pullulan hydrolase from Thermococcus kodakarensis
Authors: Rashid Naeem , Shehzad Anjum , Ahmad Nasir , Hussain Zaheer , Haider Muhammad S. 
Published: February 2019

Abstract
The starchy foods including staled or leftover bread, insect infested or damaged cereal grains and bakery wastes are usually discarded, which is a threat to public health due to extensive fungal growth. In the present study we have utilized them as raw materials for synthesis of maltose and glucose syrups using pullulan hydrolase from Thermococcus kodakarensis (TK-PUL). The novelty of the process was that whole process was completed: (i) in the absence of any liquefying amylase; (ii) without pre-gelatinization of starch; and (iii) using undisrupted E. coli cells, expressing TK-PUL gene, as a source of extremely thermostable TK-PUL protein. Since glucose and maltose can serve as precursors for a variety of biotechnological products, it is therefore anticipated that hydrolysis of starchy food wastes by TK-PUL would be highly beneficial. It will serve as cost effective measure not only to extract valuables from rubbish but also lower the level of environmental pollutants.
Archaeal and bacterial thermostable amylopullulanases: characteristic features and biotechnological applications
Authors: Satyanarayana Tulasi , Nisha Mohanan 
Published: February 2019

AbstractAmylopullulanases are endoacting bifunctional enzymes capable of hydrolyzing α-1,4- and α-1,6-glycosidic linkages in starch, amylose, pullulan, amylopectin and related oligosaccharides. These enzymes possess single or dual active site(s) for cleaving α-1,4- and α-1,6-glycosidic bonds; the former are called amylopullulanases, and the latter, α-amylase-pullulanases. These are grouped into GH13 and GH57 families based on the architecture of the catalytic domain and the number of conserved sequence regions. The amylopullulanases/α-amylasepullulanases are produced by bacteria as well as archaea, and among them, thermophilic and hyperthermophilic species are the major producers. The thermostable amylopullulanases find application in one-step starch liquefaction-saccharification to form various sugar syrups and maltooligosaccharides. The starch saccharification process catalysed by amylopullulanases minimizes the use of other amylolytic enzymes, like α-amylase and glucoamylase, thereby reducing the cost of sugar syrups. The enzymes also find applications in bread making as an anti-stale and as a detergent additive.
The Singular Perturbation Problem for a Class of Generalized Logistic Equations Under Non-classical Mixed Boundary Conditions
Authors: Fernández-Rincón Sergio , López-Gómez Julián 
Published: February 2019

Abstract
This paper studies a singular perturbation result for a class of generalized diffusive logistic equations,

d
⁢
ℒ
⁢
u

=

u
⁢
h
⁢

(
u
,
x
)

{d\mathcal{L}u=uh(u,x)}

, under non-classical mixed boundary conditions,

ℬ
⁢
u

=
0

{\mathcal{B}u=0}

on

∂
⁡
Ω

{\partial\Omega}

. Most of the precursors of this result dealt with Dirichlet boundary conditions and self-adjoint second order elliptic operators. To overcome the new technical difficulties originated by the generality of the new setting, we have characterized the regularity of

∂
⁡
Ω

{\partial\Omega}

through the regularity of the associated conormal projections and conormal distances. This seems to be a new result of a huge relevance on its own. It actually complements some classical findings of Serrin, [39], Gilbarg and Trudinger, [21], Krantz and Parks, [27], Foote, [18] and Li and Nirenberg [28] concerning the regularity of the inner distance function to the boundary.
CFTR structure, stability, function and regulation
Authors: Meng Xin , Clews Jack , Ciuta Anca D. , Martin Eleanor R. , Ford Robert C. 
Published: February 2019

Abstract
Cystic fibrosis transmembrane conductance regulator (CFTR) is a unique member of the ATP-binding cassette family of proteins because it has evolved into a channel. Mutations in CFTR cause cystic fibrosis, the most common genetic disease in people of European origin. The F508del mutation is found in about 90% of patients and here we present data that suggest its main effect is on CFTR stability rather than on the three-dimensional (3D) folded state. A survey of recent cryo-electron microscopy studies was carried out and this highlighted differences in terms of CFTR conformation despite similarities in experimental conditions. We further studied CFTR structure under various phosphorylation states and with the CFTR-interacting protein NHERF1. The coexistence of outward-facing and inward-facing conformations under a range of experimental conditions was suggested from these data. These results are discussed in terms of structural models for channel gating, and favour the model where the mostly disordered regulatory-region of the protein acts as a channel plug.
An Innovative Solution for Type Testing of Power Transformers
Authors: Singh Manohar , Telukanta Vishnuvarddhan , Meera K S 
Published: February 2019

Abstract
Type tests are essential to assess the short circuit withstand capabilities of transformer windings. The mechanical durability of power equipment are checked against the mechanical forces developed during making/breaking short circuit operations. These type tests are generally carried out in indoor transformer test laboratories. Testing of Power Transformer for size more than 200 MVA in 765/400 kV voltage class in an indoor laboratory is not economically feasible. Now a days, power transformer manufacturers are fabricating single phase auto- power transformers of size up to 630 megawatt volt ampere (MVA) rating. Type testing of these transformers in indoor laboratories is not feasible. In view of this, strong short circuit fault feeding capabilities of the national grids can be utilized for type testing of these power transformers in an online manner. However, this may affect the grid operation/control during weak grid operating conditions. Recently, National High Power Testing Laboratory is established for testing of power transformer upto of 630 MVA. This is a unique online transformer test facility for testing of 765/400/220/132 kV class power transformers. An offline simulation has been carried out in this article, to assess the impact of online type testing on the Indian National grid. In this article, an online testing scheme has been presented which enables the national grid operator to analysis the prevailing grid condition & subsequently to decide the safe rating of the power transformer for online testing. The simulated results are cross checked with field results and it is found that simulated results are close to actual field results. The concurrence of simulated and field results helped in successfully commissioning of the testing laboratory.
Temperature Effects on Thermodynamic Parameters and Solubility of Curcumin O/W Nanodispersions Using Different Thermodynamic Models
Authors: Sayyar Zahra , Jafarizadeh-Malmiri Hoda 
Published: February 2019

Abstract
Solubility of curcumin at different temperatures is of great importance in subcritical water extraction systems. We newly developed an approach for the solid–liquid equilibrium under subcritical condition to determine the solubility of curcumin. The experimental results were correlated successfully with thermodynamics models such as Van’t Hoff, modified Apelblat equation, Wilson, non-random two-liquid (NRTL) and λh equation and the interaction parameters’ values of curcumin-water were acquired. Good agreement between the experimental and calculated values with λh equation was observed at different temperatures (373.15–433.15 °K) at 1.5 bar. The obtained value of the relative average deviation was 2.29 × 10–5. The molar enthalpy (ΔH
0), entropy (ΔS
0), Gibbs energy (ΔG
0) and their relative fraction of the total process were calculated. The calculated enthalpy with the Van’t Hoff equation (25.32 kJ/mol) agreed well with the differential scanning calorimetry analysis data (26.15 kJ/mol).
The language of an inanimate narrator
Authors: Trompenaars Thijs , Hogeweg Lotte , Stoop Wessel , de Hoop Helen 
Published: February 2019

Abstract
We show by means of a corpus study that the language used by the inanimate first person narrator in the novel Specht en zoon deviates from what we would expect on the basis of the fact that the narrator is inanimate, but at the same time also differs from the language of a human narrator in the novel De wijde blik on several linguistic dimensions. Whereas the human narrator is associated strongly with action verbs, preferring the Agent role, the inanimate narrator is much more limited to the Experiencer role, predominantly associated with cognition and sensory verbs. Our results show that animacy as a linguistic concept may be refined by taking into account the myriad ways in which an entity’s conceptual animacy may be expressed: we accept the conceptual animacy of the inanimate narrator despite its inability to act on its environment, showing this need not be a requirement for animacy.
Extraordinary Bulging Mass in the Foetus - A Case Report of Bladder Exstrophy
Authors: Łosińska Joanna , Respondek-Liberska Maria 
Published: February 2019

Abstract
INTRODUCTION: Prenatal diagnosis of bladder exstrophy is extremley rare and difficult. BACKGROUND: Due to abnormal development of the cloacal membrane there is an incomplete closure of the lower abdominal wall, absence of the anterior wall of the bladder and external exposition of the posterior wall. The pubic bones are usually separated, the umbilical cord low inserted and there is abnormal external genitalia development. CASE REPORT: At 21st week of gestation of 39-year-old multigravida multipara referred by a primary care obstetrician to high-specialised centre for a detailed ultrasound examination with a suspicion of bladder absence and inferior umbilical localisation. At 29 weeks of gestation presence of bulging mass of 2 cm, between the umbilical outlet and labia was detected. At 31 weeks of gestation previously detected structure among thighs had 3 cm diameter with lateral umbilical outlet. Major labia were prominent and minor labia were within normal limits. Between two umbilical arteries with an appropriate intraabdominal course there were no transsonic area corresponding to the urinary bladder. The newborn baby was born at term in a good condition, but with an exposed bladder of 4 cm in diameter. The urethral outlet was not visualised and the female genitals were abnormal. After a month the girl underwent primary bladder exstrophy closure. Although she suffers from recurring urinary tract infections, she is in a good general condition. CONCLUSIONS: Due to prenatal diagnostics it was possible to detect and make an initial diagnosis of severe malformation. Early diagnosis allowed to prepare parents for a newborn with a defect and teach them how to take care of the baby.
Isolated Double Aortic Arch (Daa) – Prenatal Detection with Postnatal Follow-Up, Case Report and Literature Review
Authors: Murlewska Julia , Żalińska Agnieszka , Roik Danuta , Werner Bożena , Respondek-Liberska Maria 
Published: February 2019

AbstractThis case report presents a prenatal diagnosis with postnatal confirmation (by angio CT and computer reconstruction) of an isolated double aortic arch, with no blood disturbances and with no clinical symptoms after birth. Literature review was focusing on the possible symptoms in the future. Prenatal findings should be forwarded to neonatologist and pediatrician despite clinical silence.
The predictive value of serum neopterin for multiple organ dysfunction syndrome in severe burn patients
Authors: Xiong Wei , Ouyang Jun , Ci Hai , Jiang Wenping , Han Wei , Fu Yu , Tian Peigang 
Published: February 2019

Abstract
Objective To investigate the predictive value of serum neopterin for multiple organ dysfunction syndrome (MODS) in severe burn patients. Methods Seventy-six severe burn patients with burns covering a total body surface area (TBSA) above 70% were included in this study. Of the 76 patients, 29 cases developed MODS (MODS group) and the remaining 47 subjects did not (non-MODS group). From the MODS group, 12 patients died (Death group) and 17 patients survived (Survive group). The serum level of neopterin in the MODS and non-MODS groups were examined by radioimmunoassay on following 1, 3 , 7 , 14 , 21 and 28 post-burn days (PBDs). A receiver operating characteristic (ROC) curve was used to analyse the predictive value of serum neopterin for MODS and death. Results The serum neopterin level in the MODS group was significantly higher than that of non-MODS group between 3~28 PBDs (p<0.001). However, the serum neopterin levels between the MODS and non-MODS groups following 1 PBD were not statistically significant (p>0.05). The best diagnostic performance of serum neopterin for MODS occurred 14 PBDs with the prediction sensitivity and specificity of 75.86% (56.46%~89.70%) and 85.11% (71.69%~93.80%) respectively. However, serum neopterin levels had no clinical value in predicting the death of MODS patients. The area under the ROC curve (AUC) was 0.72 (0.58~0.85), 0.81 (0.71~0.92) and 0.83 (0.72~0.94) for serum neopterin as biomarker in the prediction of MODS after 3, 7 and 14 PBDs, respectively. The AUCs were 0.50 (0.27~0.73), 0.53 (0.30~0.76) and 0.56 (0.33~0.79) for serum neopterin as biomarker in prediction of death for MODS patients after 3, 7 and 14 PBDs, respectively. Conclusion The persistent and significant increase of serum neopterin level is closely related to the development of MODS in patients with severe burns. Serum neopterin is therefore a promising serological marker for MODS early diagnosis, but has little efficacy in the prediction of the likelihood of death in severe burn patients with MODS.
Trimmed Whittle estimation of the SVAR vs. filtering low-frequency fluctuations: applications to technology shocks
Authors: Lovcha Yuliya , Perez-Laborda Alejandro 
Published: February 2019

Abstract
This paper shows that the trimmed Whittle estimation of the SVAR is superior to filtering (or differencing) undesired, low-frequency fluctuations that may arise in macroeconomic data. Pre-filtering destroys the low-frequency range of the spectrum, thus biasing the estimated parameters and the responses of the variables to shocks. The proposed method, by contrast, accounts for the undesired fluctuations while overcoming these drawbacks. Furthermore, the method remains reliable even when the observed low-frequency variability has been incorrectly considered as external to the SVAR. An empirical application that examines the effect of technology shocks on hours worked is provided to illustrate the results. We find the response of hours positive and similar using both long and short-run identification restrictions, thus providing a solution to a wide debate in the business cycle literature.