bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rare‐earth titanate melt structure and glass formation
Authors: Alderman Oliver L. G. , Benmore Chris J. , Tamalonis Anthony , Weber Rick 
Published: July 2019

AbstractThe structure of rare‐earth titanate melts and glasses of composition 17RE2O3.83TiO2 have been investigated in situ by aerodynamic levitation with laser heating. Ti K‐edge X‐ray absorption near‐edge structure (XANES) spectroscopy reveals an effect of RE cation size on mean Ti‐O coordination numbers (nTiO), which increase from ∼4.8(2) in glass‐forming La titanate to ∼5.1(2) in non‐glass‐forming Sc titanate liquids. We suggest that the associated increase in OTi3 triclusters in melts bearing smaller RE cations tends to inhibit glass formation. Both XANES and high‐energy X‐ray diffraction indicate increases in nTiO as the liquids supercool and vitrify. Results are discussed in the context of alkali and alkaline‐earth titanate glasses, extending the observed dependence of nTiO on structural basicity (modifier content divided by potential) to trivalent modifiers and the molten state. We suggest that the most stable titanate glasses form close to compositions where, on average, two oxygen anions bond to each titanium, allowing a continuous, disordered Ti‐O network of bridging oxygen (OTi2), or with equal numbers of OTi3 triclusters and OTi1 non‐bridging oxygen in charge‐balance. We report on new glasses formed from praseodymium, europium, and gadolinium titanate melts, the latter being the smallest rare‐earth for which binary titanate glasses have been obtained.
Scalp ulcers – differential diagnoses that should be sought!
Authors: Shavit Eran , Alkallabi Mona , Alavi Afsaneh 
Published: July 2019

AbstractBackgroundUlceration of the scalp is an uncommon clinical presentation, and it may be caused by myriads of cutaneous etiologies such as infections, inflammatory disorders, and malignancies. We sought to reveal the underlying etiology of scalp ulcers referred to our tertiary wound healing clinic; we would also like to propose a classification for scalp ulcerations.MethodsA retrospective study was conducted in an academic tertiary wound healing clinic between January 2015 and June 2018. The study was approved by the Women’s College Hospital Institutional Research Ethics Board. We have also conducted a review of the literature to recognize the major causes of scalp ulceration reported in the literature.ResultsWe have identified a total number of 15 patients with scalp ulceration. Twelve patients with atypical scalp ulcers underwent a skin biopsy. A malignancy rate of 73% (11/15) was diagnosed histologically. The review of the literature showed 237 articles. After screening the title and the abstracts, we have selected 41 case reports for the full text review.ConclusionScalp ulcers are uncommon but important. Our sample study indicates the high frequency of malignant etiologies presenting as scalp ulcers. These results emphasize not only the need for clinicians to be on the watch for the possibility of this option but rather highlights the need for early biopsy to prevent further complications. We hope that our paper helps to shed some light on this topic and guide clinicians on how to approach scalp ulceration.
Low‐temperature sintering of single‐phase, high‐entropy carbide ceramics
Authors: Feng Lun , Fahrenholtz William G. , Hilmas Gregory E. 
Published: July 2019

AbstractDense (Hf, Zr, Ti, Ta, Nb)C high‐entropy ceramics were produced by hot pressing (HP) of carbide powders synthesized by carbothermal reduction (CTR). The relative density increased from 95% to 99.3% as the HP temperature increased from 1750°C to 1900°C. Nominally phase pure ceramics with the rock salt structure had grain sizes ranging from 0.6 µm to 1.2 µm. The mixed carbide powders were synthesized by high‐energy ball milling (HEBM) followed by CTR at 1600°C, which resulted in an average particle size of ~100 nm and an oxygen content of 0.8 wt%. Low sintering temperature, high relative densities, and fine grain sizes were achieved through the use of synthesized powders. These are the first reported results for low‐temperature densification and fine microstructure of high‐entropy carbide ceramics.
The Economic Significance of Long‐Term Plans
Authors: Kotsantonis Sakis , Rehnberg Christina , Serafeim George , Ward Bronagh , Tomlinson Brian 
Published: July 2019

The authors summarize the findings of their event study of the capital market reactions to an inaugural set of 17 CEO presentations of their ‘long‐term plans’ to institutional investors. The findings show that, although sell‐side analysts appear unresponsive to such plans, both trading volumes and stock prices exhibit significant abnormal reactions to the presentations, providing suggestive evidence that the communication of such plans conveys ‘value‐relevant’ information to investors with longer time horizons. Although based on an admittedly small sample, these findings shed light on the promise of long‐term plans and have been corroborated by analysis of the market response to the presentations of 10 more companies since the study was conducted.The authors also provide the outlines of a ‘content framework’ designed to help companies put together effective corporate plans and other long‐term disclosures. The framework is organized around nine main ‘themes,’ including policies governing capital allocation, corporate governance, and human capital development, as well as the statement of corporate purpose. After applying this framework to the 17 CEO presentations, the authors find that the more specific and forward‐looking the information disclosed in these long‐term plans, the more positive the capital market reaction.
Four Things No One Will Tell You About ESG Data
Authors: Kotsantonis Sakis , Serafeim George 
Published: July 2019

As the ESG finance field and the use of ESG data in investment decision‐making continue to grow, the authors seek to shed light on several important aspects of ESG measurement and data. This article is intended to provide a useful guide for the rapidly rising number of people entering the field. The authors focus on the following:
The sheer variety, and inconsistency, of the data and measures, and of how companies report them. Listing more than 20 different ways companies report their employee health and safety data, the authors show how such inconsistencies lead to significantly different results when looking at the same group of companies.
‘Benchmarking,’ or how data providers define companies' peer groups, can be crucial in determining the performance ranking of a company. The lack of transparency among data providers about peer group components and observed ranges for ESG metrics creates market‐wide inconsistencies and undermines their reliability.
The differences in the imputation methods used by ESG researchers and analysts to deal with vast ‘data gaps’ that span ranges of companies and time periods for different ESG metrics can cause large ‘disagreements’ among the providers, with different gap‐filling approaches leading to big discrepancies.
The disagreements among ESG data providers are not only large, but actually increase with the quantity of publicly available information. Citing a recent study showing that companies that provide more ESG disclosure tend to have more variation in their ESG ratings, the authors interpret this finding as clear evidence of the need for ‘a clearer understanding of what different ESG metrics might tell us and how they might best be institutionalized for assessing corporate performance.’
What can be done to address these problems with ESG data? Companies should ‘take control of the ESG data narrative’ by proactively shaping disclosure instead of being overwhelmed by survey requests. To that end, companies should ‘customize’ their metrics to some extent, while at the same time seeking to self‐regulate by reaching agreement with industry peers on a ‘reasonable baseline’ of standardized ESG metrics designed to achieve comparability. Investors are urged to push for more meaningful ESG disclosure by narrowing the demand for ESG data into somewhat more standardized, but still manageable metrics. Stock exchanges should consider issuing—and perhaps even mandating—guidelines for ESG disclosures designed in collaboration with companies, investors, and regulators. And data providers should come to agreement on best practices and become as transparent as possible about their methodologies and the reliability of their data.
How Board Oversight Can Drive Climate and Sustainability Performance
Authors: Ramani Veena , Ward Bronagh 
Published: July 2019

The authors present persuasive evidence that board leadership is essential for solving critical sustainability issues like climate change. As fiduciaries to investors and stewards of a company's performance and success, corporate directors have a critical role to play in providing oversight of material risks to corporate strategy and performance, especially those posed by climate change.Drawing upon a report by Ceres and KKS Advisors, the authors show that perhaps most important among best practices for companies intent on establishing effective board governance are the creation of formal board mandates for sustainability, the recruitment of directors with sustainability expertise, and the linking of executive pay to sustainability performance. The authors' study also provides compelling evidence that when companies put in place such governance features, their sustainability performance improves notably. The international banking group BNP Paribas and the electric utility Iberdrola are held up as illustrations of governance systems that are likely to be effective in helping companies respond to climate change.
An Investor Perspective on the Black Box of Corporate Social Responsibility
Authors: Fernando Chitru S. , Uysal Vahap B. , Abeysekera Amal P. 
Published: July 2019

In summarizing the findings of their recent study, the authors report findings that suggest that not all socially responsible corporate policies are likely to have the same effect on a company's ownership and value. Using environmental policy as their proxy for CSR activities, the authors classify corporate environmental practices into two categories: (1) actions that reduce the likelihood of harmful outcomes by reducing the corporate exposure to environmental risk; and (2) actions that enhance companies' perceived ‘greenness’ through investments that go beyond both legal requirements and any conceivable risk management rationale.Although both groups of environmental practices are likely to be viewed as socially beneficial, corporate expenditures that reduce a firm's environmental risk exposure are more likely to benefit shareholders by limiting the risk of losses arising from environmental accidents, lawsuits, and fines—and possibly thereby reducing the firm's cost of capital. By contrast, corporate expenditures that enhance the firm's perceived greenness by going beyond legal requirements and risk management rationales could actually reduce shareholder value.Consistent with this hypothesis, the authors find that institutional investors tend to own smaller than average percentages of both companies the authors identify as ‘toxic’ and make limited efforts to manage their environmental risk, and companies they label ‘green’ with low environmental risk exposure but relatively high CSR spending on the environment. At the same time, such investors hold larger‐than‐average positions in ‘neutral’ companies with relatively low, or effectively managed, environmental risk exposures and limited investment in ‘greenness’ programs. The authors also find that both toxic and green companies have lower (Tobin's Q) valuations than neutral companies, and that otherwise toxic companies that effectively manage their environmental risk exposures have higher valuations.
Dispersal kernels may be scalable: Implications from a plant pathogen
Authors: Farber Daniel H. , De Leenheer Patrick , Mundt Christopher C. 
Published: July 2019

AbstractAimUnderstanding how spatial scale of study affects observed dispersal patterns can provide insights to spatiotemporal population dynamics, particularly in systems with significant long‐distance dispersal (LDD). We aimed to investigate the dispersal gradients of two rusts of wheat with spores of similar size, mass and shape, over multiple spatial scales. We hypothesized that a single dispersal kernel could fit the dispersal from all spatial scales well, and that it would be possible to obtain similar results in spatiotemporal increase of disease when modelling based on differing scales.LocationCentral Oregon and St. Croix Island.TaxaPuccinia striiformis f. sp. tritici, Puccinia graminis f. sp. tritici, Triticum aestivum.MethodsWe compared empirically derived primary disease gradients of cereal rust across three spatial scales: local (inoculum source and sampling unit = 0.0254 m, spatial extent = 1.52 m) field‐wide (inoculum source = 1.52 m, sampling unit = 0.305 m and spatial extent = 91.4 m) and regional (inoculum source and sampling unit = 152 m, spatial extent = 10.5 km). We then examined whether disease spread in spatially explicit simulations depended upon the scale at which data were collected by constructing a compartmental time‐step model.ResultsThe three data sets could be fit well by a single power law dispersal kernel. Simulating epidemic spread at different spatial resolutions resulted in similar patterns of spatiotemporal spread. Dispersal kernel data obtained at one spatial scale can be used to represent spatiotemporal disease spread at a larger spatial scale.Main ConclusionsOrganisms spread by aerially dispersed small propagules that exhibit LDD may follow similar dispersal patterns over a several hundred‐ or thousand‐fold expanse of spatial scale. Given that the primary mechanisms driving aerial dispersal remains constant, it may be possible to extrapolate across scales when empirical data are unavailable at a scale of interest.
Is catchment geodiversity a useful surrogate of aquatic plant species richness?
Authors: Toivanen Maija , Hjort Jan , Heino Jani , Tukiainen Helena , Aroviita Jukka , Alahuhta Janne 
Published: July 2019

AbstractAimConserving freshwater biodiversity in a rapidly changing world requires updated planning schemes and research efforts. Geodiversity – the diversity of Earth surface forms, materials and processes – and biodiversity are interlinked at a fundamental level. This relationship is being considered in a growing number of studies, yet research from freshwater environments is scarce. We used geodiversity (rock‐type, soil‐type and geomorphological richness), local and climatic variables to explore whether geodiversity can be used as a surrogate for aquatic plant species richness in lakes and rivers.LocationFinland.TaxonAquatic plants.MethodsWe compared geodiversity variables (measured within 1‐km2 grid cells) to well‐studied local (e.g. area, alkalinity) and climate (e.g. growing degree‐days) variables, and examined the patterns between habitat types (lakes and rivers) and among all taxa and major functional groups (helophytes and hydrophytes). We modelled lake (n = 145) and river (n = 146) plant species richness with generalized linear models, and further partitioned variation to measure the independent and shared contributions of the geodiversity, climate and local environmental variable groups. As a complementary analysis, and to identify single important variables explaining variation in aquatic plant species richness, we utilized boosted regression trees.ResultsWe found a positive relationship between aquatic plant species richness and catchment geodiversity variation with recurring patterns across two different freshwater habitat types and two aquatic plant functional groups. Higher variation in geodiversity (measured at landscape scale) supported higher freshwater biodiversity (measured at the local scale) of lakes and rivers.Main conclusionsGeodiversity can be a useful addition to biodiversity modelling, and it should be considered in conservation schemes and monitoring efforts, further supporting the principle of conserving nature's stage. Yet, differences between habitats and functional groups suggest that more habitat‐specific approaches and multiple biodiversity measures should be considered. Our study is an important signpost guiding further studies on the biodiversity–geodiversity relationship in freshwater ecosystems.
Cancer has overtaken cardiovascular disease as the commonest cause of death in Scottish type 2 diabetes patients: A population‐based study (The Ayrshire Diabetes Follow‐up Cohort study)
Authors: Collier Andrew , Meney Carron , Hair Mario , Cameron Lyall , Boyle James G 
Published: July 2019

AbstractAims/IntroductionThe increased mortality risk associated with diabetes is well established. The aim of the present study was to determine the causes of death of people with type 2 diabetes in Ayrshire and Arran, Scotland, between 2009 and 2014, and compare them with the national mortality rates.Materials and MethodsThe primary causes of death were collated. The causes of death were clustered into nine categories: heart disease, stroke, infection, renal failure, respiratory disorders, cancer, mental health, decompensated diabetes and other. The total rates were compared with national rates using the standardized mortality ratio (SMR), and then individually with heart disease, cerebrovascular disease and cancer.ResultsThere were 2116 deaths with the SMR, and 145 of those were caused by type 2 diabetes (n = 16,643; 95% confidence interval 139–152; P < 0.01). The SMR was >100 in all age bands, particularly in the younger age bands (P < 0.01). The SMR was consistently higher for women (P < 0.01). The SMR for heart disease was significantly >100 for both sexes in all age bands <65 years (P < 0.05). There was no difference in mortality causes related to the duration of diabetes. The most common cause of death was cancer (27.8%), followed by heart disease (24.1%). The SMR for cancer deaths was significantly elevated in women (120, 95% CI 104–137; P < 0.05).ConclusionsThis study confirmed increased mortality risk in type 2 diabetes patients, and suggests that where cardiovascular risk factors are being treated aggressively, cancer takes on a greater importance in the cause of death. Should greater consideration now be given for cancer as a complication of diabetes?
Rating and capital structure: How do the signs affect the speed of adjustment?
Authors: Samaniego‐Medina Reyes , di Pietro Filippo 
Published: July 2019

AbstractStandard and Poor's ratings can be modified by the addition of a plus (+) or minus (−) sign to show the relative standing within each major rating category. In this paper, we analyze the influence of these signs on the speed of leverage adjustment for listed European companies in the 2004–2014 period. Our results indicate that (a) when a qualification is accompanied by a minus sign, it adjusts more slowly than qualifications either with a plus sign or without a sign; (b) when a rating has a plus sign, the adjustment is slower than when it has no sign; and (c) when a qualification is BBB‐, the speed of its leverage adjustment is close to zero. These results suggest that companies with signs in their ratings decrease their speed of adjustment to the target leverage ratio. In addition, such companies are especially concerned about a credit rating downgrade when it implies a possible loss of the degree of investment (BBB‐).
The physiological role of α‐synuclein and its relationship to Parkinson’s Disease
Authors: Sulzer David , Edwards Robert H. 
Published: July 2019

AbstractThe protein α‐synuclein has a central role in the pathogenesis of Parkinson’s disease (PD). In this review, we discuss recent results concerning its primary function, which appears to be on cell membranes. The pre‐synaptic location of synuclein has suggested a role in neurotransmitter release and it apparently associates with synaptic vesicles because of their high curvature. Indeed, synuclein over‐expression inhibits synaptic vesicle exocytosis. However, loss of synuclein has not yet been shown to have a major effect on synaptic transmission. Consistent with work showing that synuclein can promote as well as sense membrane curvature, recent analysis of synuclein triple knockout mice now shows that synuclein accelerates dilation of the exocytic fusion pore. This form of regulation affects primarily the release of slowly discharged lumenal cargo such as neural peptides, but presumably also contributes to maintenance of the release site.
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This article is part of the Special Issue “Synuclein”.
Randomized, controlled, crossover trial of prevention of antibiotic‐induced gastrointestinal signs using a synbiotic mixture in healthy research dogs
Authors: Whittemore Jacqueline C. , Moyers Tamberlyn D. , Price Joshua M. 
Published: July 2019

AbstractBackgroundSynbiotics decrease antibiotic‐associated gastrointestinal signs (AAGS) in cats, but data supporting synbiotic use to ameliorate AAGS in dogs are lacking.ObjectivesTo determine if administration of synbiotics mitigates AAGS in dogs.AnimalsTwenty‐two healthy research dogs.MethodsRandomized, double‐blinded, placebo‐controlled, 2‐way, 2‐period, crossover study with an 8‐week washout period. Each period included a 1‐week baseline and 3‐week treatment phase. Dogs received enrofloxacin (10 mg/kg PO q24h) and metronidazole (12.5 mg/kg PO q12h), followed 1 hour later by a bacterial/yeast synbiotic combination or placebo. Food intake, vomiting, and fecal score were compared using repeated‐measures crossover analyses, with P < .05 considered significant.ResultsHyporexia, vomiting, and diarrhea occurred in 41% (95% confidence interval [CI], 21‐64), 77% (95% CI, 55‐92), and 100% (95% CI, 85‐100) of dogs, respectively, during the first treatment period. Derangements in food intake were smaller in both periods for dogs receiving synbiotics (F‐value, 5.1; P = .04) with treatment‐by‐period interactions (F‐value, 6.0; P = .02). Days of vomiting differed over time (F‐value, 4.7; P = .006). Fecal scores increased over time (F‐value, 33.5; P < .001), were lower during period 2 (F‐value, 14.5; P = .001), and had treatment‐by‐period effects (F‐value, 4.8; P = .04).Conclusions and Clinical ImportanceEnrofloxacin/metronidazole administration is associated with a high frequency of AAGS. Synbiotic administration decreases food intake derangements. The presence of milder AAGS in period 2 suggests that clinical effects of synbiotics persist >9 weeks after discontinuation, mitigating AAGS in dogs being treated with antibiotics followed by placebo.
Marker‐assisted breeding for improvement of anaerobic germination in japonica rice (Oryza sativa)
Authors: Kim Suk‐Man , Kim Choon‐Song , Jeong Ji‐Ung , Reinke Russell F. , Jeong Jong‐Min 
Published: July 2019

AbstractDirect seeding is increasingly being practiced in rice cultivation areas because it saves labour and reduces cost of production and management. In this study, four japonica‐type breeding lines were developed from a cross of a japonica cultivar and an AG‐tolerant donor, KHO, using marker‐assisted selection. Validation of the target genes AG1 and AG2 in the selected lines was examined by PCR analysis and the background recovery rate by the recurrent parent was confirmed by genotyping using a 6K SNP chip. Compared to the recurrent, the survival rates of the selected lines were improved in a range from 33% to 115% in three conditions; in particular, the survival rate was increased in more than twice that of the recurrent parent under the hypoxic condition. The main agronomic trait, yield and quality‐related traits were similar to those of the recurrent parent. The use of these lines will contribute to the expansion of the cultivation area due to the proven economic benefits of direct seeding in Korea.