bluuebunny/crossref_metadata_2025_split huggingface dataset:
Healthcare costs and outcomes for patients undergoing tracheostomy in an Australian tertiary level referral hospital
Authors: Bihari Shailesh , Prakash Shivesh , Hakendorf Paul , Horwood Christopher MacBryde , Tarasenko Steve , Holt Andrew W , Ratcliffe Julie , Bersten Andrew D 
Published: March 2018

Objective Patients undergoing tracheostomy represent a unique cohort, as often they have prolonged hospital stay, require multi-disciplinary, resource-intensive care, and may have poor outcomes. Currently, there is a lack of data around overall healthcare cost for these patients and their outcomes in terms of morbidity and mortality. The objective of the study was to estimate healthcare costs and outcomes associated in tracheostomy patients at a tertiary level hospital in South Australia. Design Retrospective review of prospectively collected data in patients who underwent tracheostomy between July 2009 and May 2015. Methods Overall healthcare-associated costs, length of mechanical ventilation, length of intensive care unit stay, and mortality rates were assessed. Results A total of 454 patients with tracheostomies were examined. Majority of the tracheostomies (n = 386 (85%)) were performed in intensive care unit patients, predominantly using bedside percutaneous approach (85%). The median length of hospital stay was 44 (29–63) days and the in-hospital mortality rate was 20%. Overall total cost of managing a patient with tracheostomy was median $192,184 (inter-quartile range $122560–$295553); mean 225,200 (range $5942–$1046675) Australian dollars. There were no statistically significant differences in any of the measured outcomes, including costs, between patients who underwent percutaneous versus surgical tracheostomy and patients who underwent early versus late tracheostomy in their intensive care unit stay. Factors that predicted (adjusted R2 = 0.53) the cost per patient were intensive care unit length of stay and hospital length of stay. Conclusion Hospitalised patients undergoing tracheostomy experience high morbidity and mortality and typically experience highly resource-intensive and costly healthcare.
Effect of postoperative pneumatic compression after volar plate fixation of distal radial fractures: a randomized controlled trial
Authors: Alkner Björn A. , Halvardsson Christina , Bråkenhielm Gustaf , Eskilsson Therese , Andersson Erika , Fritzell Peter 
Published: March 2018

We investigated the difference between postoperative rehabilitation with or without adjunctive intermittent pneumatic compression therapy following distal radial fracture treated with volar plating. A total of 115 patients were randomized to a control or to an experimental group. After 4 weeks of immobilization the experimental group received intermittent pneumatic compression therapy in addition to conventional postoperative rehabilitation. Primary outcome up to 1 year postoperatively was assessed using the Canadian Occupational Performance Measure. No significant differences between groups were found. There were no clinically relevant differences regarding the secondary outcome measures swelling, strength, pain and flexibility. We conclude that postoperative intermittent pneumatic compression treatment had no major benefits. The results of the present study do not support general use of intermittent pneumatic compression initiated 4 weeks following volar plating surgery for distal radial fracture. Level of evidence: I
Is the Bare Spot reliable for the bone loss measurement?
Authors: Ramos Max Rogerio Freitas , San Junior Yonder Archanjo Ching , Alves Luiz Henrique Pereira , Cruz Flavio Carvalho , Mansur Henrique 
Published: March 2018

Background To evaluate the reliability of the Bare Spot (BS) as an anatomical landmark for the intra-operative definition of bone loss in anterior shoulder instability. Methods The distances from the BS to the anterior (BS-A), posterior (BS-P) and inferior margins of the glenoid cavity were determined both under arthroscopic visualization and by an open approach in 20 shoulders. Results The BS did not coincide with the centre of the glenoid cavity of the studied shoulders because the BS-P distance was greater than the BS-A distance ( p < 0.05) and was located 40% closer to the anterior margin. The authors suggest a correction factor: BP-A × 1.25/BP-P = 1. Conclusions The BS is located at a mean distance of 40% of the joint diameter, relative to the anterior margin of the glenoid. This point may be used as a landmark, using a correction factor of its mostly anterior positioning. Arthroscopy was reliable for bone measurements of the shoulder joint.
Awareness of diabetic retinopathy among people with diabetes in Jeddah, Saudi Arabia
Authors: Alzahrani Sami H. , Bakarman Marwan A. , Alqahtani Saleh M. , Alqahtani Maha S. , Butt Nadeem Shafique , Salawati Emad M. , Alkatheri Ahmad , Malik Ahmad Azam , Saad Khaled 
Published: March 2018

Background: Diabetic retinopathy (DR) is the most common microvascular complication of diabetes mellitus (DM) and the foremost cause of blindness. This study aimed to assess the level of awareness of DR and its related risk factors among patients with DM in Jeddah, Saudi Arabia. Methods: A cross-sectional study was conducted among patients with DM attending primary health care centers at the Ministry of Health in Jeddah. A structured, pretested, self-administered questionnaire was used to collect information on the sociodemographic and DM- and DR-related characteristics of the patients. Results: A total of 377 patients were enrolled. About 82.6% of the patients were aware that DM can affect their eyes, and they listed physicians, ophthalmologists, television, and family members as common sources of information on the topic. About 36% of the patients reported that their doctors had not advised them about it. More than half responded that they did not feel their vision to be affected by DM. More than 58% had never been diagnosed with DR. About 35% did not go to their eye checkups, even though around 59% thought that DR could lead to blindness. Of the 64% of patients whose DM was well controlled, 11% and 25% listed surgery and laser treatment, respectively, as available treatment options for DR. The following factors were found to be significant in relation to the subjects’ awareness that DM can affect their eyes: the patients’ perception of their doctors’ advice about DR; the experience of having their vision affected by DM; the knowledge that DR may lead to blindness; the practice of going to eye checkups. Conclusions: Despite having good awareness about DM and its effects on eyes, the patients exhibited a relative lack of awareness about DR. Considering the association of DR with DM, its increasing magnitude is a potential burden on the community and health systems.
Ten-Year Incidence of Sport and Recreation Injuries Resulting in Major Trauma or Death in Victoria, Australia, 2005-2015
Authors: Ekegren Christina L. , Beck Ben , Simpson Pamela M. , Gabbe Belinda J. 
Published: March 2018

Background: Sports injuries that result in major trauma or death are associated with significant health care burden and societal costs. An understanding of changes in injury trends, and their drivers, is needed to implement policy aimed at risk reduction and injury prevention. To date, population-level reporting has not been available regarding trends in serious sport and recreation injuries anywhere in Australia over such an extended period, nor have any studies of this length captured comprehensive, long-term data on all sports-related major trauma internationally. Purpose: To describe the incidence of sport and active recreation injuries resulting in major trauma or death over a 10-year period (July 2005 to June 2015) in the state of Victoria, Australia. Study Design: Descriptive epidemiological study. Methods: All sport and active recreation–related major trauma cases and deaths in Victoria, Australia, over a 10-year period were extracted from the population-level Victorian State Trauma Registry and the National Coroners Information System. Poisson regression analysis was used to examine trends in the incidence of sport and active recreation–related major trauma and death. Results: The 10-year study period entailed 2847 nonfatal major trauma cases and 614 deaths (including 96 in-hospital deaths). The highest frequencies of major trauma cases and deaths were in cycling, motor sports, and equestrian activities. The participation-adjusted major trauma and death rate was 12.2 per 100,000 participants per year over the study period. An 8% increase was noted in the rate of nonfatal major trauma (incident rate ratio [IRR], 1.08; 95% CI, 1.06-1.10; P < .001) and a 7% decrease in the death rate (IRR, 0.93; 95% CI, 0.90-0.97; P < .001). Significant increases were found in the rates of major trauma (including deaths) in equestrian activities, motor sports, and cycling. Conclusion: The death rate from sport and active recreation decreased by more than half over the course of 10 years in Victoria, while the rate of nonfatal major trauma almost doubled. This increase is largely attributable to equestrian activities, motor sports, and cycling. Study findings highlight the need to prioritize investments in the prevention of trauma in these activities.
Multi-Institutional, Prospective Clinical Utility Study Evaluating the Impact of the 92-Gene Assay (CancerTYPE ID) on Final Diagnosis and Treatment Planning in Patients With Metastatic Cancer With an Unknown or Unclear Diagnosis
Authors: Thomas Sachdev P. , Jacobson Lauren E. , Victorio Anthony R. , Operaña Theresa N. , Schroeder Brock E. , Schnabel Catherine A. , Braiteh Fadi 
Published: March 2018

Purpose Metastatic cancers of unknown primary or with unclear diagnoses pose diagnostic and management challenges, often leading to poor outcomes. Studies of the 92-gene assay have demonstrated improved diagnostic accuracy compared with standard pathology techniques and improved survival in patients treated on the basis of assay results. The current study assessed the clinical impact of the 92-gene assay on diagnostic and treatment decisions for patients with unknown or uncertain diagnoses. Methods Patients in this prospective, multi-institutional, decision-impact study included those for whom the 92-gene assay was ordered as part of routine care. Participating physicians completed electronic case report forms that contained standardized, specialty-specific questionnaires. Data collection included patient and tumor characteristics and clinical history. The key study objective of clinical impact was calculated on the basis of changes in final diagnosis and treatment after testing. Results Data collection included 444 patients, 107 physicians (73 oncologists and 34 pathologists), and 28 sites. Molecular diagnoses from 22 different tumor types and subtypes across all cases were provided in 95.5% of patients with a reportable result (n = 397). Physicians reported that the 92-gene assay was used broadly for diagnostic dilemmas that ranged from single suspected tumor type (29%) to a differential diagnosis of two or more suspected tumor types (30%) or cancers of unknown primary (41%). Integration of 92-gene assay results led to a change in the recommended treatment in 47% of patients. Conclusion Findings from this clinical utility study demonstrate that the 92-gene assay led to a change in treatment decisions in every other patient case. These data additionally define the role of this assay in clinical practice and strongly support the consideration of molecular tumor typing in the diagnosis and treatment planning of patients with metastatic cancer with unknown or uncertain diagnosis.
Reordered (Sorted) Spectra. A Tool for Understanding Pattern Recognition Entropy (PRE) and Spectra in General
Authors: Chatterjee Shiladitya , Linford Matthew R 
Published: March 2018

Abstract
Pattern Recognition Entropy (PRE) is a summary statistic for comparing and understanding spectra. Here we introduce the concept of the ‘reordered spectrum’ in the context of PRE as an intuitive, visual representation of spectra. The shapes of reordered (sorted) spectra correlate with their PRE values and help explain them. We illustrate these concepts with liquid chromatography-mass spectrometry (LC-MS), time-of-flight secondary ion mass spectrometry (ToF-SIMS), and X-ray photoelectron spectroscopy (XPS) spectra. Reordered spectra should have value beyond PRE for comparing and understanding spectra.
City-based action to reduce harmful alcohol use: review of reviews
Authors: Anderson Peter , Jané-Llopis Eva , Hasan Omer Syed Muhammad , Rehm Jürgen 
Published: March 2018

Background: The World Health Organization global strategy on alcohol called for municipal policies to reduce the harmful use of alcohol. Yet, there is limited evidence that documents the impact of city-level alcohol policies. Methods: Review of reviews for all years to July 2017. Searches on OVID Medline, Healthstar, Embase, PsycINFO, AMED, Social Work Abstracts, CAB Abstracts, Mental Measurements Yearbook, Health and Psychosocial Instruments, International Pharmaceutical Abstracts, International Political Science Abstracts, NASW Clinical Register, and Epub Ahead of Print databases. All reviews that address adults, without language or date restrictions resulting from combining the terms (“review” or “literature review” or “review literature” or “data pooling” or “comparative study” or “systematic review” or “meta-analysis” or “pooled analysis”), and “alcohol”, and “intervention” and (“municipal” or “city” or “community”). Results: Five relevant reviews were identified. Studies in the reviews were all from high income countries and focussed on the acute consequences of drinking, usually with one target intervention, commonly bars, media, or drink-driving. No studies in the reviews reported the impact of comprehensive city-based action. One community cluster randomized controlled trial in Australia, published after the reviews, failed to find convincing evidence of an impact of community-based interventions in reducing adult harmful use of alcohol. Conclusions: To date, with one exception, the impact of adult-oriented comprehensive community and municipal action to reduce the harmful use of alcohol has not been studied. The one exception failed to find a convincing effect. We conclude with recommendations for closing this evidence gap.
Reescritura de Guimarães Rosa por Rinaldo de Fernandes: entre A hora e vez de Augusto Matraga e Grande sertão: veredas
Authors: Ramalho de Farias Sonia Lúcia 
Published: March 2018

O artigo apresenta o interessante conto de Rinaldo Fernandes, Sariema, produzido a partir de A hora e vez de Augusto Matraga, em que Fernandes realiza uma releitura do enredo, com diferente foco narrativo, desta vez, feminino, e que produz a sua versão dos fatos, muitas vezes, invertendo-os. A partir daí, realiza-se uma análise sobre o curioso diálogo textual que se estabelece.
Application of BS4-enzyme on the methane production from mixture of cattle manures and waste paper
Authors: Haryati Tuti , Sinurat A. P. , Listian B. , Hamid H. , Purwadaria T. 
Published: March 2018

<p class="abstrak2">Cellulose from abundant newspaper waste could be transformed into methane through anaerobic fermentation. This research was carried out to compare the gas production including methane between samples containing feces and waste paper mixture as inoculum and substrate, respectively and added with and without BS4 enzyme. The enzyme was produced in Indonesian Research Institute of Animal Produce (IRIAP) by growing Eupenicillium javanicum BS4 in coconut meals. There were three treatments, i.e., 30% manure (M30); 15 % manure + 15 % paper waste (MP 30); MP30 + 3 mL BS4 enzyme equal to 0.42 U/g dry matter (MPE30) The percentage of waste papers addition in feces was calculated on dry matter (DM) basis and every treatment had five replications. Total gas and methane productions were measured weekly, while dry matter losses were determined during 5 week fermentation. Interactions between treatments and incubation time were analyzed using completely randomized design each week. Kind of substrates influenced both total gas and methane productions during incubation time. Both waste papers and enzyme addition enhanced gas production. The highest total gas and methane productions for five weeks incubation were highly significantly observed (P&lt;0.01) in MP30 and MPE30 compared to M30. Addition of enzyme significantly increased total gas and methane productions in the first week. The highest methane and total gas yield/g dry matter were obtained by BS4 enzyme addition. It was concluded that BS4 enzyme is good in accelerating and increasing the transformation efficiency of waste paper and manure mixture for biogas production.</p><p><strong>Key Words</strong>: Methane, Fibrenolytic-Enzyme, Waste Papers, Cattle Manures</p>
Weight estimation of empty carcass and carcass cuts weight of female SenSi-1 Agrinak chicken
Authors: Hidayat Cecep , Iskandar Sofjan 
Published: March 2018

<p class="A04-abstrak3">SenSi-1 Agrinak chicken is Indonesian local chicken that was selected for growth rate for six generations. The aim of this study was to estimate of carcass weight and carcass cuts of female SenSi-1 Agrinak chicken, based on age and live weight. The chicks were reared intensively in colony wire cages and they were slaughtered with Islamic method when they reached age of 5, 8 and 15 weeks. Empty carcass and carcass cuts were weight in fresh. Data were analyzed using correlation and regression analysis method. Results showed that the live weight had a high positive correlation to carcass weight and carcass cuts weight of female SenSi-1 Agrinak chickens aged 5, 8 and 15 weeks. Estimation of live weight, carcass, carcass cuts, gizzard, liver and abdominal fat of female SenSi-1 Agrinak, using mathematical model, showed small value differences (0.09 - 4.43%) from the actual data. It was concluded that female SenSi-1 Agrinak chicken’s carcass weight and carcass cuts, could be estimated based on of age in days and live-body weight in gram without slaughtering.</p><p class="A04-abstrak3"><span lang="EN"> </span></p><p class="A04-abstrak3"> </p>
Supplementation of molasses and branched-chain amino acid to increase in vitro digestibility of ammoniated corn cob in ruminants feed
Authors: Puastuti Wisri , Yulistiani Dwi , Handiwirawan Eko 
Published: March 2018

<p>Corn cob contains high fiber and lignin which causes low nutritive value. The objective of the study was to improve the digestibility of ammoniated corn cob (CC) by supplementation of molasses and branched-chain amino acid (BCAA: valine, leucine and isoleucine). CC was processed by addition 3% urea. The first stage of in vitro test was done with 4 levels of molases 0, 5, 10 and 15% of dry matter (DM) of CC. The experiment was carried out using complete randomized design with 4 treatments and 4 replications. The second stage was also in vitro study of supplementation of two levels each for valine = V, leucine = L and isoleucine = I namely 0.1 and 0.2% of DM of ammoniated CC. There were 8 treatments combination of the BCAA as follow: A = V0.1 L0.1 I0.1; E = V0.2 L0.1 I0.1; B = V0.1 L0.1 I0.2; F = V0.2 L0.1 I0.2; C = V0.1 L0.2 I0.1; G = V0.2 L0.2 I0.1; D = V0.1 L0.2 I0.2; H = V0.2 L0.2 I0.2 and 1 control (V0.0 L0.0 I0.0). The experiments were done using completely randomized design with 9 treatments and 3 replications. The results showed that treated CC with urea was able to increase protein content by 78% (increased from 3.34% to 5.95%) while neutral detergent fiber (NDF) decreased by 15.4%, acid detergent fiber (ADF) by 7.9% and lignin 16.7%. Addition of molasses in ammoniated CC increased DM digestibility (P &lt;0.05) by 7.5% (41.9 vs 43.51-46.26%) and NDF by 17.7% (38.41 vs 43.76 – 46.31%). Supplementation of BCAA resulted in the highest DM, OM and NDF digestibility (P &lt;0.05) in the treatment of A, C, D and G. Compare to treament I, the digestibility of DM, OM and NDF in G treatment increased by 31.4%, 27.5% and 36.5%, respectively and produced the highest total population of rumen bacterial of 12.4 x 109 colonies /ml. It can be concluded that the digestibility of ammoniated CC increased by the supplementation of 5% molases and BCAA combination consisted of 0.2% valine, 0.2% leucine and 0.1% isoleucine.</p><p> </p><p>Kata kunci: Tongkol jagung, amoniasi, molases, asam amino bercabang.</p>
Un caso de resistencia de Rhipicephalus microplus (Acari: Ixodidae) al fipronil detectado en pruebas de campo en el este de Santiago del Estero, Argentina
Authors: NAVA Santiago , MOREL Nicolás , MANGOLD Atilio J. , GUGLIELMONE Alberto A. 
Published: March 2018

En este trabajo se describe la resistencia de una población Rhipicephalus microplus resistente al fipronil 1% (ECTOLINE®) en condiciones de campo en el este de Santiago del Estero, Argentina. Las pruebas fueron realizadas a modo de réplicas en dos establecimientos: “Establecimiento A” y “Establecimiento B”. En el Establecimiento A las diferencias en los niveles de infestación con garrapatas entre los grupos tratado y control nunca fueron estadísticamente significativas. Los porcentajes de eficacia oscilaron entre 27,3% y 69,3%. En el Establecimiento B las diferencias entre los grupos tratado y control fueron significativas, con porcentajes de eficacia aumentando de 87,6% el día 2 post-tratamiento a 95,4% el día 7 post-tratamiento. Las tasas de eclosión de los huevos originados de las teleóginas colectadas de los grupos tratados y control en el Establecimiento A fueron similares. La aplicación de fipronil 1% en el Establecimiento B tuvo una eficacia global prácticamente absoluta, porque si bien la eficacia terapéutica no alcanzó el 100%, la viabilidad reproductiva de las teleóginas obtenidas de los bovinos tratados fue nula. Los resultados del presente trabajo constituyen el primer registro publicado de una población de R. microplus resistente al fipronil 1% en condiciones de campo en Argentina.
Propuesta de implementación de un sistema de gestión ambiental, articulado con el “SIGME” del Ministerio de Minas y Energía
Authors: Barros Orozco Manuel Orlando 
Published: March 2018

Este proyecto de investigación presenta una propuesta para la implementación de un sistema de gestión ambiental en el Ministerio de Minas y Energía basado en el cumplimiento de los requisitos establecidos en la norma ISO 14001:2015. El proceso investigativo se enmarca dentro de los conceptos del pensamiento sistémico, la gestión ambiental y la integración de los sistemas de gestión. Para la elaboración de la propuesta fue necesario, en primer lugar, efectuar una revisión ambiental inicial, bajo los parámetros de la GTC 93, en segundo lugar, con los resultados obtenidos de la revisión ambiental, se establecieron las brechas entre lo que pide la norma y lo que actualmente tiene la entidad, para que en último lugar se pudiera construir una propuesta que se ajuste al contexto del Ministerio de Minas y Energía. Esta propuesta tiene un alcance a las actividades que se desarrollan en el ámbito administrativo, tales como el mantenimiento, aseo, gestión del parque automotor y sobre todo, las actividades de oficina que generan consumos de energía y agua, y que a su vez, producen residuos.