bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inherent criminogenesis in business organisations
Authors: Glebovskiy Alexander 
Published: February 2019

Purpose
This paper aims to discuss criminogenic elements and processes inherently presented in business organisations that affect the emergence of crime committed in or by business organisations.

Design/methodology/approach
This conceptual paper, based on relevant literature regarding a range of crime-coercive and crime-facilitative elements and forces that promote corporate crime, considers business organisations as a cogent unit of analysis to discuss the causation and origin of corporate crime.

Findings
Business organisations are, per se, criminogenic, i.e. companies are latently prone to committing crime, but are not necessarily criminal. By seeking to achieve commercial goals, companies can unintentionally create an atmosphere that invites crimes and unethical conduct. Organisational criminality is not primarily influenced by deviance in individual behaviour, but is a product of the organisation’s criminogenic settings and environment. Criminal activity arises from contact with criminogenic systems and employees’ adaption to organisational behaviours that do not meet the highest ethical and moral standards.

Research limitations/implications
This is a theoretical analysis, lacking empirical research.

Practical implications
This study can help anti-fraud and compliance practitioners to develop anti-fraud strategies to prevent corporate crime at its source and further discussion on the causes of corporate misconduct and progresses the debate on the sources of illegal and unethical behaviour displayed in, and by, business organisations.

Originality/value
This paper highlights intrinsic features of business organisations that influence companies and employees to engage in illegal activities, malpractice and unethical behaviour and provides a conceptual framework and insights into the realm of inherent criminogenesis within business organisations and how this is shaped by organisations themselves.
Artificial intelligence: accelerator or panacea for financial crime?
Authors: Yeoh Peter 
Published: February 2019

PurposeThis purpose of this viewpoint is to address the intended good and unintended bad impacts of artificial intelligence (AI) applications in financial crime.Design/methodology/approachThe paper relied primarily on secondary data resources, business cases and relevant laws and regulations, and it used a legal-economics perspective.FindingsCurrent AI systems could function as antidotes or accelerator of financial crime, in particular cybercrime. Research suggests criminal law could be applied via three approaches to curb these cybercrimes. However, others considered this to be an inappropriate mechanism to hold AI agents accountable, as present AI systems were not deemed capable of making ethically informed choices. Instead, administrative sanctions would be considered more appropriate for now. While keeping vigilance against AI malicious acts, regulatory authorities in the USA and the UK have opted largely for the innovation-friendly, market-oriented, permissionless approach over the state-interventionist stance so as to maintain their global competitive edge in this domain.Originality/valueThe paper reinforced the growing arguments that AI applications should be deployed more as panacea for financial crimes rather than being abused as crime accelerators. There equally though is the need for both public and private sectors to be mindful of the unintended negative, harmful consequences to society, especially those connected to cybercrime. This implied the further need to beef up attention and resources to help mitigate these risks.
Marco normativo de los apartamentos y viviendas de uso turistico en España
Authors: del Busto Eugenio , Ceballos Martín María Matilde , Pérez Guerra Raúl 
Published: February 2019

Propósito
El presente trabajo indaga acerca del estado actual de la legislación de alojamiento turístico bajo la modalidad de apartamentos turísticos y viviendas de uso turístico en España.

Diseño/metodología/enfoque
Se trata de una investigación exploratoria centrada en el análisis de una tipología específica dentro del subsector hospedaje. Se basa en un trabajo de gabinete (recopilación bibliográfica y normativa).

Recomendaciones
Como resultado, se advierte que la legislación de alojamiento turístico bajo la modalidad de apartamentos y viviendas de uso turístico en España ha experimentado un creciente desarrollo en la última década y presenta un importante nivel de dispersión, un alto grado de heterogeneidad en los criterios de categorización, y en algunos casos falta de incorporación de aspectos claves como la accesibilidad, la calidad y la sostenibilidad.

Originalidad/valor
La originalidad del estudio se fundamenta en el análisis comparativo de la regulación que las Comunidades Autónomas realizan de esta modalidad de alojamiento turístico denominada en la mayoría de las normativas analizadas de apartamentos turísticos y viviendas de uso turístico. El trabajo comprende un estudio actualizado de la legislación autonómica en la materia.
Noise transformation
Authors: Lacey Jordan , Pink Sarah , Harvey Lawrence , Moore Stephan 
Published: February 2019

PurposeThe purpose of this paper is to report the results of an industry-funded qualitative interdisciplinary research project that has produced a new approach to motorway noise management called “noise transformation”.Design/methodology/approachFour iterative design tests guided by listening as methodology. These included field recordings, laboratory tests and two field tests. Field tests were conducted in combination with ethnographers, who verified community responses to field-based transformations.FindingsTransformation requires an audible perception of both background and introduced sounds in all instances. Transformation creates a 1–2 dB increase in background sound levels, making it counterintuitive to traditional noise attenuation approaches. Noise transformation is an electroacoustic soundscape design method that treats noise as a “design material”. When listening to motorway noise transformations, participants were actually experiencing another rendering of a sound that they had already acquired a degree of attunement to. Thus, they experienced transformations as somehow familiar or normal and easy to feel comfortable with.Originality/valueNoise transformation is a new approach to noise management. Typically, noise management focusses on reduction in dB levels. Noise transformation focusses on changing the perceptual impact of noise to make it less annoying. It brings together urban design, composition and ethnography as a means to think about the future design of outdoor environments affected by motorway traffic noise, and should be of interests to planners, designers and artists. The authors have structured the paper around listening as methodology, through which both design and ethnography outcomes were achieved.
Purchase decision and purchase delay of hedonic and utilitarian products in the face of time pressure and multiplicity of options
Authors: Basso Kenny , Duschitz Caroline da Costa , Giacomazzi Cassandra Marcon , Sonego Monique , Rossi Carlos Alberto Vargas , Reck Danúbia 
Published: February 2019

Purpose
Time pressure may change how people behave. The multiplicity of options and the nature of the products, hedonic or utilitarian, might increase the complexity of the choice and alter the effects of time pressure. Combining both factors, the purpose of this paper is to verify the moderating role played by the nature of the products observing the relationship between interaction (time pressure × multiplicity of options) and choice delay.

Design/methodology/approach
A two-level factorial experimental design was applied (time pressure: with; without) × 2 (number of alternatives: two; six) × 2 (type of purchase: hedonic; utilitarian), with mixed design, considering the purchase delay a dependent variable.

Findings
The results signal that the nature of the products moderates the effects of the interaction between time pressure and choice overload in purchase delay. Utilitarian purchases are more susceptible to the effects of time pressure and options overload than hedonic purchases.

Originality/value
The interaction between time pressure and choice overload, researched in previous works, influences in different ways the purchase of utilitarian or hedonic products. This differentiation, taking into consideration the type of product, brings new perspectives on the purchase decision process and provides theoretical and practical information on the effects of information overload and time pressure over the consumer decision-making process.
Summer performance, comfort, and heat stress in structural timber buildings under moderate weather conditions
Authors: Adekunle Timothy Oluseun 
Published: February 2019

Purpose
The purpose of this paper is to examine the Summer performance, comfort, and heat stress in structural timber buildings. The research utilises building simulation as a tool to investigate the performance of the case study buildings under non-extreme weather conditions.

Design/methodology/approach
The research explores three UK sites using the test reference year (TRY) weather files for the current and future weather conditions. The study focuses on the Summer performance and heat stress in non-extreme weather conditions; therefore, the Design Summer Year (DSY) weather files are not used for the simulations. The simulation data are calibrated and validated using the measured data from the field study.

Findings
The results revealed the mean predicted temperatures varied from 20.2–20.8°C for the 2000s. The mean temperatures for the 2030s ranged from 23.1 to 24.2°C. Higher temperatures are predicted at the buildings in the Southeast site than the Midlands and the Northwest sites. The results revealed that there is no significant improvement in the thermal environment when the floor area and the floor-to-ceiling height are increased. However, the study showed that the integration of different design interventions can improve the future performance and resilience of the buildings in various weather conditions.

Research limitations/implications
By applying the wet-bulb globe temperature (WBGT) and the Universal Thermal Comfort Index (UTCI) mathematical models to calculate the heat stress at the buildings, the study proposes the WBGT of 20.0°C and the UTCI of 24.1°C as possible heat stress indicators for occupants of the buildings in the 2030s.

Practical implications
On the one hand, the results revealed the maximum temperatures in some of the case study buildings exceed the comfort threshold (28°C). On the other hand, the study showed that occupants of the buildings are not prone to extreme Summertime overheating and heat stress under moderate weather conditions. However, different outcomes may be predicted if DSY weather files for the selected sites are considered.

Originality/value
This study is the first reported work to explore building simulation and mathematical equations to investigate Summer performance, comfort and heat stress indexes in timber buildings under moderate weather conditions in different regional sites in the UK.
Knowledge sharing
Authors: Fauzi Muhammad Ashraf , Nya-Ling Christine Tan , Thursamy Ramayah , Ojo Adedapo Oluwaseyi 
Published: February 2019

Purpose
Academics research productivity is the pinnacle issue of higher learning institution (HLI) quest for providing the best service for the community and a country’s as a whole. Being productive in their area of expertise will determine how far HLI can challenge for the best education in the world. In lieu of this, knowledge sharing (KS) behavior determinants are assessed to determine what factors that can contribute to academic’s research productivity.

Design/methodology/approach
A quota sampling method was applied in selecting academics from public and private universities in Malaysia. A partial least square structural equation modelling (PLS-SEM) was used for analysis.

Findings
The results show that academics productivity explained variance is 22.6 per cent. This suggests that academics KS behavior has substantial impact on research productivity. As for determinants of academic’s attitude, academics commitment, trust and social network constituted an explained variance of 36.4 per cent. Management support has an explained variance of 38.7 per cent towards subjective norm, while facilitating condition and social media has an explained variance of 26.5 per cent towards perceived behavioral control (PBC). Academics KS intention and KS behavior explained variance were 62.1 and 47.1 per cent, respectively.

Research limitations/implications
All the hypotheses result in significant relationship except for H1, commitment toward attitude. The impact of this study will be discussed in term of its theoretical and managerial perspectives.

Originality/value
The KS behavior in a multiracial and multinational country in Malaysia can be a benchmark for Asian countries in general.
Ustekinumab for skin reactions associated with anti‐tumor necrosis factor‐α agents in patients with inflammatory bowel diseases: A single‐center retrospective study
Authors: Ezzedine Khaled , Visseaux Laetitia , Cadiot Guillaume , Brixi Hedia , Bernard Philippe , Reguiai Ziad 
Published: February 2019

AbstractAnti‐tumor necrosis factor (TNF)‐α agents may induce skin reactions, in particular in patients with inflammatory bowel diseases (IBD). The objective of this study was to determine the efficacy of ustekinumab in these patients. IBD patients facing therapeutic issues because of cutaneous reactions or tolerance issues, consequently treated with ustekinumab in our department, were included. Retrospective review of case records and clinical photographs was carried out. Twenty‐six patients were included. Twenty‐three patients were treated for Crohn's disease and three for ulcerative colitis. Fourteen patients presented psoriasiform lesions, nine eczematiform lesions, four anaphylactoid reactions, two alopecia areata‐like lesions, one injection‐site reaction, one cutaneous polyarteritis nodosa and five other skin reactions. Most of them resolved under ustekinumab. In detail, eczematiform lesions completely resolved in all cases, psoriasiform lesions completely resolved in 12 cases (85.7%) and had partial response in two cases (14.3%). Two cases of alopecia areata showed complete response (complete hair regrowth). Fourteen patients showed complete digestive response, 10 patients partial digestive response (seven of which needed IBD treatment optimization) and only two failure. In conclusion, ustekinumab is a drug of choice in patients with IBD who cannot tolerate TNF blockers.
Pharmacokinetics, tissue distribution, plasma protein binding, and metabolism study of mefunidone, a novel pirfenidone derivative
Authors: Han Xuhua , Li Fang , Wen Zhou , Ma Yuehui , Wang Lei , Cheng Zeneng 
Published: February 2019

SummaryMefunidone (MFD), a novel derivation of pirfenidone (PFD), exhibits promising anti‐renal fibrosis activity. To avoid early development failures and attrition in clinical phase 1, an evaluation of the preclinical pharmacokinetic (PK) properties of MFD was conducted in this study. The absolute bioavailability was evaluated in Sprague Dawley rats and cynomolgus monkeys, who received an intragastric or intravenous administration at the dose of 31.25 mg/kg and 10 mg/kg, respectively. Tissue distribution and plasma protein binding studies were performed to evaluate the distribution characteristics of MFD. The enzymes involved in the metabolism of MFD were assayed by calculating the inhibition rate using the in vitro incubation system of human liver microsomes. The metabolic pathway of MFD was also examined in the in vitro incubation system as well as in rats in vivo. The results revealed satisfactory absorption of MFD in vivo, with an absolute bioavailability of MFD in rats and monkeys of approximately 77.2% and 70.0%, respectively. MFD was rapidly distributed to all tissues and was highly concentrated in the kidney, which was the target organ of MFD. The plasma protein binding rates in rat, monkey, and human plasma were 36.40%–41.68%, 30.88%–63.92%, and 37.75%–57.77%, respectively. MFD was primarily metabolized by the enzymes CYP3A4, CYP2C9, and CYP2C8. The metabolic pathway of MFD is nitrogen demethylation of the pyridine ring of the MFD nucleus, hydroxylation of the aromatic ring, and demethylation of the piperazine ring. In conclusion, MFD exhibited good PK properties in the initial preclinical PK study. The results strongly support further research to investigate the potential of MFD as a clinical anti‐renal fibrosis drug.
In situ plankton community respiration measurements show low respiratory quotients in a eutrophic lake
Authors: Münzner Karla , Berggren Martin 
Published: February 2019

SummaryPlanktonic community respiration is an important carbon cycling process, typically quantified by converting measured values of dissolved O2 consumption rates into CO2 production rates assuming a respiratory quotient of 1 (RQ = CO2 per O2 by moles). However, the true variability in planktonic RQs between different aquatic ecosystems is poorly understood. We conducted in situ RQ measurements in a eutrophic lake dominated by algal‐derived substances and found that RQs were significantly below 1. In fact, many RQ values were extremely low (0.2–0.6), below theoretical RQs for oxidation of algal organic matter substrates (0.7–0.8), suggesting that other factors than substrate control need to be considered to understand the RQ. This view was further supported by lack of correlations between RQ and microbial variables known to be strongly substrate dependent, including bacterial growth efficiency and the functional capacity of the bacterioplankton community to degrade different compounds. Based on the measured dynamics in methane and nutrient pools, we discuss that methane oxidation and nitrification likely occurred in the lake, contributing to the unusually low RQs. Our findings demonstrate that planktonic RQs in productive lakes can systematically be below 1, suggesting that CO2 emissions from these lakes may currently be overestimated.
Transcriptomics analysis defines global cellular response ofAgrobacterium tumefaciens5A to arsenite exposure regulated through the histidine kinases PhoR and AioS
Authors: Rawle Rachel A. , Kang Yoon‐Suk , Bothner Brian , Wang Gejiao , McDermott Timothy R. 
Published: February 2019

SummaryIn environments where arsenic and microbes coexist, microbes are the principal drivers of arsenic speciation, which directly affects bioavailability, toxicity and bioaccumulation. Speciation reactions influence arsenic behaviour in environmental systems, directly affecting human and agricultural exposures. Arsenite oxidation decreases arsenic toxicity and mobility in the environment, and therefore understanding its regulation and overall influence on cellular metabolism is of significant interest. The arsenite oxidase (AioBA) is regulated by a three‐component signal transduction system AioXSR, which is in turn regulated by the phosphate stress response, with PhoR acting as the master regulator. Using RNA‐sequencing, we characterized the global effects of arsenite on gene expression inAgrobacterium tumefaciens5A. To further elucidate regulatory controls, mutant strains for histidine kinases PhoR and AioS were employed, and illustrate that in addition to arsenic metabolism, a host of other functional responses are regulated in parallel. Impacted functions include arsenic and phosphate metabolism, carbohydrate metabolism, solute transport systems and iron metabolism, in addition to others. These findings contribute significantly to the current understanding of the metabolic impact and genetic circuitry involved during arsenite exposure in bacteria. This informs how arsenic contamination will impact microbial activities involving several biogeochemical cycles in nature.
The Australian Economy in 2018–2019: Convergence in Economic Activity across Australia
Authors: Nguyen Viet H. , Wang Jiao 
Published: February 2019

AbstractEconomic activity in Australia continued to improve in 2017–2018 with growth spreading across the mainland state economies. Labour market conditions in Australia improved markedly in 2017–2018 while the inflation rate was steady around the lower end of the Reserve Bank of Australia's 2–3 per cent target band. Real wage growth was weak and is likely to remain weak in 2018–2019, putting downward pressure on household consumption. Output growth in 2018–2019 is likely to be solid with prospects of the Chinese economy and trade tensions between China and the United States posing the greatest downside risk to the Australian economy.
Representing the compromise: How institutions serve government support coalitions in European Union policy making
Authors: FRANCHINO FABIO , WRATIL CHRISTOPHER 
Published: February 2019

AbstractThis article presents an original model of policy making by multiparty coalitions at the international level. Specifically, it analyses how domestic institutions serve parties in enforcing policy compromises onto national ministers negotiating legislation in the European Union (EU). In contrast to existing research on coalition politics, the model accounts for the benefits of not only legislative but also executive institutions and incorporates opposition parties as pivotal actors under minority governments. Ministers propose policy positions at the EU level that represent domestic coalition compromises when cabinet participation, executive coordination and parliamentary oversight of EU affairs make it cheap for coalition partners to challenge the minister's position and when ideological divisiveness increases the incentive to do so. Statistical analyses of 1,694 policy positions taken by ministers from 22 member states in the Council of the EU provide strong empirical evidence for the model. The results support the claim of executive dominance in EU policy making but also highlight that, where institutions are strong, ministers represent domestic coalition compromises rather than their own positions.
Evaluating diffusion‐weighted magnetic resonance imaging for target volume delineation in head and neck radiotherapy
Authors: Cardoso Michael , Min Myo , Jameson Michael , Tang Simon , Rumley Christopher , Fowler Allan , Estall Vanessa , Pogson Elise , Holloway Lois , Forstner Dion 
Published: February 2019

AbstractIntroductionInter‐observer variability (IOV) in target volume delineation is a source of error in head and neck radiotherapy. Diffusion‐weighted imaging (DWI) has been shown to be useful in detecting recurrent head and neck cancer. This study aims to determine whether DWI improves target volume delineation and IOV.MethodsFour radiation oncologists delineated the gross tumour volume (GTV) for ten head and neck cancer patients. Delineation was performed on CT alone as well as fused image sets which incorporated fluorodeoxyglucose (FDG)‐positron emission tomography (PET) and magnetic resonance imaging (MRI) in the form of CT/PET, CT/PET/T2W and CT/PET/T2W/DWI image sets. Analysis of the variability of contour volumes was completed by comparison to the simultaneous truth and performance level estimation (STAPLE) volumes. The DICE Similarity Coefficient (DSC) and other IOV metrics for each observer's contour were compared to the STAPLE for each patient and image dataset. A DWI usability scoresheet for delineation was completed.ResultsThe CT/PET/T2W/DWI mean GTV volume of 13.37 (10.35–16.39)cm3 was shown to be different to the mean GTV of 10.92 (8.32–13.51)cm3 when using CT alone (P < 0.001). The GTV DSC amongst observers for CT alone was 0.72 (0.65–0.79), CT/PET was 0.73 (0.67–0.80), CT/PET/T2W was 0.71 (0.64–0.77) and CT/PET/T2W/DWI was 0.69 (0.61–0.75).ConclusionMean GTVs with the addition of DWI had slightly larger volumes compared to standard CT and CT/PET volumes. DWI may add supplemental visual information for GTV delineation while having a small impact on IOV, therefore potentially improving target volume delineation.