bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Noether Theorem on Unimprovable Conservation Laws for Vector-Valued Optimization Problems in Control Theory
Authors: Torres Delfim F. M. 
Published: October 2019

Abstract
We obtain a version of Noether's invariance theorem for optimal control problems with a finite number of cost functionals. The result is obtained by formulating E. Noether's result for optimal control problems subject to isoperimetric constraints, and then using the unimprovable (Pareto) notion of optimality. It was A. Gugushvili who drew the author's attention to a result of this kind that was posed as an open mathematical question of a great interest in applications of control engineering.
Fixed Point Techniques and Stability for Neutral Nonlinear Differential Equations with Unbounded Delays
Authors: Djoudi Ahcene , Khemis Rabah 
Published: October 2019

Abstract
We use the contraction mapping theorem to obtain stability results of the scalar nonlinear neutral differential equation with functional delay
𝑥′(𝑡) = –𝑎𝑥(𝑡) + 𝑏(𝑡)𝑥2(𝑡 – 𝑟(𝑡)) + 𝑐(𝑡)𝑥(𝑡 – 𝑟(𝑡))𝑥′(𝑡 – 𝑟(𝑡)).
Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia
Authors: Yu Jin , Zhu Hong , Taheri Saeid , Mondy William , Bonilha Leonardo , Magwood Gayenell S. , Lackland Daniel , Adams Robert J. , Kindy Mark S. 
Published: October 2019

Serum amyloid A (SAA) proteins are acute-phase reactant associated with high-density lipoprotein (HDL) particles and increase in the plasma 1000-fold during inflammation. Recent studies have implicated SAAs in innate immunity and various disorders; however, the precise mechanism eludes us. Previous studies have shown SAAs are elevated following stroke and cerebral ischemia, and our studies demonstrated that SAA-deficient mice reduce inflammation and infarct volumes in a mouse stroke model. Our studies demonstrate that SAA increases the cytokine interleukin-1β (IL-1β), which is mediated by Nod-like receptor protein 3 (NLRP3) inflammasome, cathepsin B, and caspase-1 and may play a role in the pathogenesis of neurological disorders. SAA induced the expression of NLRP3, which mediated IL-1β induction in murine BV-2 cells and both sex primary mouse microglial cells, in a dose- and time-dependent fashion. Inhibition or KO of the NLRP3 in microglia prevented the increase in IL-1β.N-acetyl-l-cysteine and mito-TEMPO blocked the induction of IL-1β by inhibiting ROS with SAA treatment. In addition, inhibition of cathepsin B with different drugs or microglia from CatB-deficient mice attenuated inflammasome activation. Our studies suggest that the impact of SAA on inflammasome stimulation is mediated in part by the receptor for advanced glycation endproducts and Toll-like receptor proteins 2 and 4. SAA induced inflammatory cytokines and an M1 phenotype in the microglial cells while downregulating anti-inflammation M2 phenotype. These studies suggest that brain injury to can elicit a systemic inflammatory response mediated through SAA that contributes to the pathological outcomes.SIGNIFICANCE STATEMENTIn the present study, serum amyloid A can induce that activation of the inflammasome in microglial cells and give rise to IL-1β release, which can further inflammation in the brain following neurological diseases. The also presents a novel target for therapeutic approaches in stroke.
Counting surface branched covers
Authors: Petronio Carlo , Sarti Filippo 
Published: October 2019

Abstract
To a branched cover f between orientable surfaces one can associate a certain branch datum, that encodes the combinatorics of the cover. This satisfies a compatibility condition called the Riemann-Hurwitz relation. The old but still partly unsolved Hurwitz problem asks whether for a given abstract compatible branch datum there exists a branched cover f such that . One can actually refine this problem and ask how many these f's exist, but one must of course decide what restrictions one puts on such f’s, and choose an equivalence relation up to which one regards them. As it turns out, quite a few natural choices for this relation are possible. In this short note we carefully analyze all these choices and show that the number of actually distinct ones is only three. To see that these three choices are indeed different from each other we employ Grothendieck's dessins d'enfant.
On the problem of Pillai with Padovan numbers and powers of 3
Authors: Ddamulira Mahadi 
Published: October 2019

Abstract
Let {P n}n≥0 be the sequence of Padovan numbers defined by P0 = 0, P1 = 1, P2 = 1, and Pn+3 = Pn+1 + Pn for all n ≥ 0. In this paper, we find all integers c admitting at least two representations as a difference between a Padovan number and a power of 3.
Interpreting Accuracy and Visual Processing of Numbers in Professional and Student Interpreters: an Eye-tracking Study
Authors: Stachowiak-Szymczak Katarzyna , Korpal Paweł 
Published: October 2019

Abstract
Simultaneous interpreting is a cognitively demanding task, based on performing several activities concurrently (Gile 1995; Seeber 2011). While multitasking itself is challenging, there are numerous tasks which make interpreting even more difficult, such as rendering of numbers and proper names, or dealing with a speaker's strong accent (Gile 2009). Among these, number interpreting is cognitively taxing since numerical data cannot be derived from the context and it needs to be rendered in a word-to-word manner (Mazza 2001). In our study, we aimed to examine cognitive load involved in number interpreting and to verify whether access to visual materials in the form of slides increases number interpreting accuracy in simultaneous interpreting performed by professional interpreters (N = 26) and interpreting trainees (N = 22). We used a remote EyeLink 1000+ eye-tracker to measure fixation count, mean fixation duration, and gaze time. The participants interpreted two short speeches from English into Polish, both containing 10 numerals. Slides were provided for one of the presentations. Our results show that novices are characterised by longer fixations and they provide a less accurate interpretation than professional interpreters. In addition, access to slides increases number interpreting accuracy. The results obtained might be a valuable contribution to studies on visual processing in simultaneous interpreting, number interpreting as a competence, as well as interpreter training.
Egy deréktáji fájdalommal kapcsolatos betegségspecifikus tudást felmérő külföldi kérdőív hazai, magyar nyelvű validálása
Authors: Kovács-Babócsay Bianka , Makai Alexandra , Szilágyi Brigitta , Tardi Péter , Ács Pongrác , Velényi Anita , Rébék-Nagy Gábor , Járomi Melinda 
Published: October 2019

Abstract: Introduction: Many disease-specific questionnaires, which analyze patients’ functional status, quality of life or the progression of the disease, have been validated in Hungarian. The low back pain (LBP) patients’ knowledge about their problem has not been measured by an officially validated Hungarian tool. Aim: The aim of our study was to translate and validate the Low Back Pain Knowledge Questionnaire (LKQ) and to assess its validity and reliability. Method: We used the translation-back translation method as the first step. Then we used a synthesis of the back translations reviewed by independent translators. We enrolled 218 people in our study: 101 of them were chronic LBP patients and 73 acute LBP patients. For the validation process, we used the Roland–Morris Disability Index to compare our questionnaire. We calculated Cronbach’s alpha values and correlation coefficients. Results: The Hungarian version of LKQ correlated well with the Roland–Morris Index and it proved to be a valid questionnaire (correlation coefficient: –0.393; Cronbach’s alpha value 0.894). Conclusion: We found the Hungarian version of LKQ a valid and reliable tool to measure patients’ knowledge about LBP. We recommend future studies should apply bigger and more homogenous populations to assess LBP disease-specific knowledge in this country. Orv Hetil. 2019; 160(42): 1663–1672.
A gastrointestinalis traktusból migrált, lenyelt idegen testek esetei
Authors: Balázs Ákos , Vass Tamás , Tárnoki Dávid , Baranyai Zsolt 
Published: October 2019

Abstract: Migration of swallowed foreign bodies from the gastrointestinal tract is a rare phenomenon compared with the total number of ingestions. In the reported two cases, the serious septic condition indicated urgent surgical intervention. We found a piece of wire swallowed a few months earlier in the right lobe of the liver and the retroperitoneum in case one, and a piece of wire in the pericardium, which migrated from the stomach through the left lobe of the liver, in case two. Abscesses and phlegmonae were found in the retroperitoneum and then in the femoral region requiring a reoperation in case one, and in the liver and pericardium in case two. After the evacuation of abscesses, both patients made full recovery. Diagnostic difficulties and therapeutic challenges served the reasons to present these cases. Orv Hetil. 2019; 160(42): 1677–1681.
PERSONEL GÜÇLENDİRMENİN İŞ TATMİNİNE ETKİSİ: YARDIMCI YARGI PERSONELİ ÜZERİNE BİR ARAŞTIRMA
Authors: Eskibina Yılmaz 
Published: October 2019

Bu çalışmanın temel amacı, personel güçlendirme
uygulamalarının yardımcı yargı personellerinin iş tatmini üzerindeki etkisini
ölçmektir. Bu amaçla, Düzce Adliyesi ve mülhakat adliyelerinde (Akçakoca ve
Yığılca) yardımcı yargı personelleri üzerinde bir araştırma yapılmıştır.
Veriler anket tekniği aracılığıyla toplanmış, sonuçlar SPPS aracılığıyla test
edilmiştir.

Personel güçlendirme anketinde yer alan 25 ifade;
Spreitzer (1995) güçlendirme ölçeği ve iş tatmini anketinde yer alan 15 ifade;
Schwepker (2001) iş tatmini ölçeği esas alınarak; Çavuş (2006), Şahin
(2007), Pelit (2008), Allanazarov
(2009), Veranyurt (2009), Durmaz (2011) ve Somuncuoğlu (2013) yüksek lisans ve
doktora tezlerinden derlenmiştir. Yapılan faktör analizleri personel
güçlendirmeyi üçe, iş tatminini ise ikiye ayırmıştır. Çok yönlü regrasyon
analiziyle güçlendirme faktörlerinin iş tatmini faktörleri üzerindeki etkisi
ölçülmüştür. Yapılan analizler sonucunda davanışsal güçlendirme hariç, yapısal
ve psikolojik güçlendirmenin yardımcı yargı personelinin iş tatmini üzerinde
etkisi olduğu kanıtlanmıştır.
Tradução e imitação: correspondências formal e funcional para o hexâmetro e o dístico elegíaco greco-latinos em língua portuguesa nos séculos XVI e XVII
Authors: Gonçalves Willamy Fernandes 
Published: October 2019

O presente artigo examina como, a partir das primeiras influências do humanismo italiano, os autores portugueses traduziram e imitaram os gêneros antigos. Examina especificamente o modo como esses autores buscaram correspondentes métricos e estróficos portugueses para reproduzir aspectos formais ou funcionais dos metros antigos. Tendo como base os conceitos de correspondência funcional e formal apresentados por Britto (2016), compara os metros vernáculos aos antigos quanto à forma e aos contextos em que são utilizados. Conclui que o uso de correspondências funcionais foi predominante nesse período, apontando, entretanto, para o caráter relativo dessas duas formas de correspondência e para a dinâmica que subjaz ao processo de apropriação de formas estrangeiras.
correspondências métricas; hexâmetro; dístico elegíaco; metros portugueses; séculos XVI e XVII.
Keywords:
Negative pressure wound therapy as a „bridge” forthe final reconstruction of tissue defect following adegloving injury of the forearm – a case report
Authors: Ratnicka Izabela , Kondej Karolina , Jończyk Justyna , Graczyk Magdalena , Chrzanowska Barbara , Jankau Jerzy 
Published: October 2019

Degloving injuries are traumatic avulsions usually resulting in large areas of soft tissue defects. The injury involves separation of skin and subcutaneous tissue from fascia and muscles. The complex nature of these injuries requires a patient-oriented multidisciplinary surgical approach and a wide variety of therapeutic options. Negative pressure wound therapy can be of benefit at every stage of the long-lasting treatment.
In this paper, we present a case of a 29-year-old male after an occupational accident with a conveyor belt leading to a degloving injury of the right forearm treated in the Department of Plastic Surgery of the Medical University in Gdańsk.
The use of NPWT, hyperbaric oxygen therapy, dermal regeneration templates, skin grafting, and early rehabilitation resulted in an excellent functional and aesthetic outcome.
Electrosurgery Induced Femoral Stem Fracture in Total Hip Arthroplasty
Authors: Aepli Martin , Meier Christoph , Wahl Peter 
Published: October 2019

Case:
We present a case of a broken titanium alloy (Ti-6Al-7Nb) femoral stem 4 years after revision total hip arthroplasty (THA) (head exchange M to XL for instability). Material analysis showed a superficial anomaly on the superior neck surface caused by local melting with an electrosurgical knife. This lesion presumably acted as a stress riser and was the initiation site of a fatigue fracture, with typical features on the fracture surface.

Conclusions:
The use of electrosurgical knives in stem retaining THA revision surgery should be avoided, especially for surgical dissection in close proximity to the femoral stem.
Dispanserization monitoring for HIV-infected patients in the Siberian Federal District in 2013–2017
Authors: Dovgopolyuk E. S. , Levakhina L. I. , Tyumentsev A. T. , Pasechnik O. A. 
Published: October 2019

According to UNAIDS, 1.4 million people are living with HIV in Eastern Europe and Central Asia, 75% of them in Russia. International guidelines recommend regular clinical evaluation of HIV-infected patients, which is achieved through follow-up. Purpose of the study: to characterize the quality of follow-up observation of HIV patients in the Siberian Federal District for the five-year period from 2013 to 2017. Materials and methods. A retrospective descriptive-assessment epidemiological study for the period 2013–2017 was conducted in the Siberian Federal District, in which dispensary observation indicators were most affected by improving the epidemiological situation associated with the spread of HIV infection. Results. The HIV infection in the Siberian Federal District increased during the period under review by 62,4% and reached 1328,5 per 100 thousand population. The prevalence of HIV infection at the beginning of 2018 was 679.0 per 100 thousand population (with an average Russian indicator of 430,2). The SFO accounted for 20,7% of all HIV cases (n = 130 595), which were registered at specialized medical organizations in the Russian Federation. The coverage of HIVinfected patients with clinical observation reached the target value and amounted to 88,2%. The number of patients who were examined to determine the immune status and viral load increased almost 2 times. At the same time, the proportion of HIV-infected people receiving antiretroviral therapy was at the level of 39,8%, which is 4,2% lower than the target values. The proportion of patients surveyed for tuberculosis among those who underwent medical examination in 2017 remains at the level of 87,8%, which does not stabilize the incidence of tuberculosis infection. The number of HIV-infected patients with a diagnosis of active tuberculosis increased 1,4 times to 17 610 in 2017 (10,9% of the number of patients). Conclusion. In the context of the continuing increase in the incidence of HIV infection in the population and an increase in the number of patients in need of various types of medical care, additional measures are needed to improve the quality and effectiveness of follow-up observation of patients with HIV infection.
Calibrating Field-Scale Uncertainties to Local Data: Is the Learning Being Overgeneralized?
Authors: He Jincong , Reynolds Albert C. , Tanaka Shusei , Wen Xian-Huan , Kamath Jairam 
Published: October 2019

Summary
A common pitfall in probabilistic history matching is omitting the local variation of spatial uncertainties and falsely generalizing the learning from local data to the entire field. This can lead to radical overestimation of uncertainty reduction and bad reservoir-management decisions. In this paper, we propose a methodology to quantify and correct for the error that arises from the omission of local variation in probabilistic history matching.
Most performance metrics in an oil field, such as the original oil in place (OOIP) and the estimated ultimate recovery (EUR), are field-scale objective functions that depend on properties (e.g., porosity) over the entire field. On the other hand, many measurement data from wells [e.g., bottomhole pressure (BHP)] are mainly sensitive to the reservoir properties near the locations where they are measured, and thus they are susceptible to local variations of reservoir properties. Calibrating field-scale objective functions to local well data without properly characterizing the local variation can overestimate the uncertainty reduction of field-scale objective functions. In this paper, we derived formulas to quantify errors in the posterior cumulative distribution functions (CDFs) of the objective functions resulting from the omission of local variation. We also provide a way to correct for the error and to recover the true posterior CDFs.
Through theoretical derivation, we show that the modeling error that arises from the omission of local variation is dependent on the magnitude of the global and local variations of the uncertain properties (e.g., porosity). The larger the local variation relative to the global variation, the larger the error in the estimated posterior distributions. The error also depends on the variogram of the local variation and the detection range of the data. The error is larger for cases with a long variogram for the local variation and a short data-detection range. In addition, the modeling errors for different measurement data points can be highly correlated even when the measurement errors for these data are independent. To correct for this modeling error, analytical and empirical formulas are proposed that have been shown to greatly improve the accuracy of the posterior distributions in a number of cases.
To the best of our knowledge, this is the first time that the modeling error from the omission of local variation in the probabilistic history-matching process has been quantified and corrected. The methodology proposed could help improve the reliability of the result from probabilistic history matching.
Association between Toxoplasma gondii infection and thyroid dysfunction: a case-control seroprevalence study
Authors: Alvarado-Esqu Cosme , Ramos-Nevarez Agar , Guido-Arreola Carlos Alberto , Cerrillo-Soto Sandra Margarita , Pérez-Álamos Alma Rosa , Estrada-Martínez Sergio , Gutierrez-Martinez Verónica Dayali , Sifuentes-Alvarez Antonio , Ramírez-Valles Eda Guadalupe , Contreras-Cisneros Edith 
Published: October 2019

Abstract
Background: The association between Toxoplasma gondii infection and thyroid disease has been poorly studied. Therefore, we sought to determine the association between T. gondii seropositivity and thyroid dysfunction.
Methods: We performed an age- and gender-matched case-control study of 176 patients suffering from hypothyroidism (n=161) or hyperthyroidism (n=15) and 528 control subjects without these diseases in a public hospital in Durango City, Mexico. Anti- Toxoplasma IgG antibodies were determined in sera from cases and controls using a commercially available enzyme-linked immunoassay.
Results: Anti- T. gondii IgG antibodies were found in 11 (6.3%) of 176 patients suffering from thyroid dysfunction and in 48 (9.1%) of 528 control subjects (OR=0.66; 95% CI: 0.33-1.31; P =0.23). Stratification by two groups of age (50 years and younger, and 51 year and older) showed that the youngest group of patients with thyroid dysfunction had a significantly lower seroprevalence of T. gondii infection than its age- and gender-matched control group (1/83: 1.2% vs 23/257: 8.6%; OR=0.12; 95% CI: 0.01-0.93; P =0.01). This stratification also showed that the youngest group of patients with hypothyroidism had a significantly lower seroprevalence of T. gondii infection than its age- and gender matched control group (0/75: 0% vs 21/233: 9.0%; P =0.003).
Conclusions: Our results suggest that thyroid dysfunction is not associated with seropositivity to T. gondii in general; however, in young (50 years or less) patients, a negative association between infection and thyroid dysfunction and hypothyroidism was found. Further research to confirm this negative association is needed.
Legal and Policy Requirements of Basic Health Insurance Package to Achieve Universal Health Coverage in a developing country
Authors: Hayati Ramin , Kabir Mohammad Javad , Kavosi Zahra , Bastani Peivand , Sobhani Ghasem , nasab Hamide Javadi 
Published: October 2019

Abstract
Objectives: This study has analyzed the policy-making requirements related to basic health insurance package at the national level with a systematic view. Results: All the documents presented since the enactment of universal health insurance in Iran from 1994 to 2017 were included applying Scott method for assuring meaningfulness, authenticity, credibility and representativeness. Then, content analysis was conducted applying MAXQDA10. The legal and policy requirements related to basic health insurance package were summarized into 3 main themes and 11 subthemes. The main themes include three kinds of requirements at three level of Third party insurer, Health care provider and Citizen/population that contains 5 (financing insurance package, organizational structure, tariffing and purchasing the benefit packages and integration of policies and precedents), 4 (determining the necessities, provision of services, rules relating to implementation and covered services) and 2 (expanded coverage of population and insurance premiums) sub themes respectively. According to the results, Iranian policy makers should notice three axes of third party insurers, health providers and population of the country to prepare an appropriate basic benefit package based on local needs for all the people that can access with no financial barriers in order to be sure of achieving UHC.
Analgosedation during flexible fiberoptic bronchoscopy: Comparing the clinical effectiveness and safety of remifentanil versus midazolam/propofol
Authors: Lee Hyun , Choe Yeong Hun , Park Seung Yong 
Published: October 2019

Abstract
Background: There are limited data regarding the efficacy and safety of remifentanil sedation for diagnostic bronchoscopy.
Methods: A retrospective study of 186 patients who underwent diagnostic bronchoscopy at Chonbuk National University Hospital was performed. Patients were classified into the remifentanil group and midazolam/propofol group according to the drugs used during bronchoscopy. The aim of this study was to evaluate the clinical efficacy and safety of remifentanil by comparing it with those of the conventional drugs, midazolam and propofol. Results: Of the 186 patients, 111 patients received remifentanil and 75 received midazolam/propofol during the bronchoscopy. The proportion of patients who required bronchoscopy for endobronchial inspection alone was significantly higher in the midazolam/propofol group than in the remifentanil group (93.3% vs. 71.2%; p < 0.001). In contrast, the proportion of patients who required more invasive procedures, such as bronchoscopic biopsy, bronchoalveolar lavage, or transbronchial lung biopsy, was significantly higher in the remifentanil group than in the midazolam/propofol group (27.8% vs. 6.7%; p < 0.001). The recovery time was significantly shorter in the remifentanil group than in the midazolam/propofol group (mean 6.4 min vs. 11.6 min, p < 0.001). There was no significant difference between the groups with regard to safety events including desaturation, hypotension, and arrhythmia.
Conclusions: Despite the higher proportion of patients who underwent more invasive procedures in the remifentanil group than in the midazolam/propofol group, there was no significant difference in safety events between the groups. Those in the remifentanil group also demonstrated a faster recovery time than those in the midazolam/propofol group.