bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atrophy-related corticospinal changes in advanced Parkinson's disease are associated with the genetic etiology of the disease
Authors: Dayan Roy , Bick Atira S , Weill Caroline , Bauer Max , Erdman Halen Baker , Israel Zvi , Bergman Hagai , Levin Netta , Arkadir David 
Published: November 2024

Background Compensatory mechanisms in Parkinson's disease (PD) are thought to explain the temporal delay between the beginning of the neurodegenerative process and the appearance of clinical signs. The enhanced structural integrity of the corticospinal tract was previously suggested as one of these mechanisms. Objective To understand the relations between corticospinal tract integrity and the anatomical, clinical, electrophysiological, and genetic PD characteristics. Methods We analyzed diffusion tensor imaging (DTI) fractional anisotropy (FA) data from 40 genotyped patients with PD (18 without known genetic cause, 11 with LRRK2-PD and 11 with GBA-PD) who were candidates for subthalamic deep brain stimulation (STN-DBS) and from 25 healthy, age-matched, controls. Results PD is associated with higher corticospinal FA values (p < 0.001) that are negatively correlated with the disease duration (p = 0.032), confirming previous results. Higher FA values are negatively correlated with cerebral grey matter volumes (p < 0.001) but not with the motor or cognitive PD characteristics, or with the subthalamic beta-oscillatory activity measured intra-operatively. Increased corticospinal FA values are strongly affected by the genetic etiology of PD, with higher values in the monogenic forms of the disease (p < 0.001). The compensatory index, calculated by dividing the corticostriatal FA value by the cerebral grey matter volume, is highest in GBA-PD (p < 0.001) at the time of evaluation for STN-DBS. Conclusions The genetic etiology of PD strongly shapes corticospinal tract changes along with disease-duration and cerebral grey matter atrophy. The changes may serve as compensatory mechanism.
Aproximaciones fenomenológicas a la mímesis positiva y a la mímesis amorosa
Authors: Ruelle Gómez Adriana 
Published: November 2024

El artículo rastrea algunos de los momentos argumentativos en perspectiva fenomenológica propuestos por Martha Reineke a favor de la mímesis positiva y Rebecca Adams de la mímesis amorosa. La primera, por identificar una fenomenología que aparece en los primeros análisis literarios de Girard. La segunda, por modelar una propuesta de la mímesis amorosa, el "paradigma de la participación intersubjetiva", en el que subyace un apartado fenomenológico basado en la epifanía que un capítulo de Star Trek la inspiró para la modelación de la mímesis amorosa.
Studi Literatur: Analisis Manajemen Laba dan Kinerja Keuangan Perusahaan Pengakuisisi Sebelum dan Sesudah Merger dan Akuisisi
Authors: Sari Nursaidah Imelda , Setiasih Hartantri 
Published: November 2024

Tujuan. Studi ini dilakukan dengan tujuan untuk melakukan kajian literatur mengenai manajemen laba dan kinerja keuangan perusahaan pengakuisisi sebelum dan sesudah merger akuisisi
Metode. Studi ini berjenis deskriptif kualitatif dengan menggunakan metode Systematic Literature Review. Sebagai cara untuk mengumpulkan teori-teori atau literatur yang relevan dengan kata kunci kinerja keuangan perusahaan sebelum dan sesudah merger dan akuisisi. Peneliti kemudian menjabarkannya melalui tabel review yang mencakup nama penulis, tahun terbit, metode penelitian yang digunakan, serta hasil penelitian yang ditemukan. Berdasarkan review jurnal tersebut, peneliti mengambil beberapa simpulan.
Hasil. Setelah dilakukan analisis, diperoleh hasil bahwa terjadi perbedaan atau adanya pengaruh finansial perusahaan sebelum sesudah merger dan akuisisi. Terjadinya peningkatan dan penurunan pada rasio-rasio keuangan perusahaan sebelum dan setelah merger dan akuisisi tergantung kepada pengelolaan sumber daya yang dimiliki ataupun kebijakan masing-masing perusahaan tersebut.
Implikasi. Dengan adanya studi ini diharapkan dapat membantu untuk penelitian selanjutnya sebagai salah satu bahan literasi yang digunakan dalam menyelesaikan penelitiannya mengenai analisis manajemen laba dan kinerja perusahaan sebelum dan sesudah merger dan akuisisi.
Kinerja Karyawan Ditinjau dari Motivasi, Lingkungan dan Disiplin Kerja Karyawan Studi Kasus PT Delta Merlin Sandang Tektile IV Sukoharjo
Authors: Rahma Devi Pradhita , Mursito Bambang , Mariyam Siti 
Published: November 2024

Tujuan. Tujuan ini bertujuan untuk menguji pengaruh motivasi, lingkungan dan disiplin kerja terhadap karyawan PT Delta Merlin Sandang Tekstile IV Sukoharjo.
Metode. Penelitian ini menerapkan metode deskriptif kuantitatif dan dilaksanakan pada PT Delta Merlin Sandang Tekstile IV Sukoharjo selama periode Oktober hingga Desember 2023. Metode pengambilan sampel yang digunakan adalah simple random sampling dengan jumlah karyawan sebanyak 375 dalam populasi dan 94 sebagai sampel. Variabel bebas dalam penelitian ini mencakup motivasi (X1), lingkungan (X2), dan disiplin kerja (X3), sedangkan variabel terikatnya adalah kinerja karyawan (Y). Teknik pengumpulan data melibatkan observasi, dokumentasi, kuesioner, wawancara, dan studi pustaka. Uji instrumen dilakukan untuk memastikan validitas dan reliabilitas data. Analisis data dilakukan melalui pendekatan deskriptif, serta uji asumsi klasik seperti uji normalitas, multikolinearitas, dan heterokedastisitas. Uji hipotesis menggunakan uji F (secara simultan), uji t (secara parsial), uji koefisien determinasi (R2), dan regresi linier berganda.
Hasil. Secara parsial motivasi, lingkungan dan disiplin kerja berpengaruh positif dan signifikan terhadap kinerja karyawan PT Delta Merlin Sandanf Tekstile IV Sukoharjo. Secara simultan motivasi, lingkungan dan disiplin kerja berpengaruh positif dan signifikan terhadap kinerja karyawan PT Delta Merlin Sandang Tekstile IV Sukoharjo.
Implikasi. Penelitian ini menunjukkan bahwa untuk meningkatkan kinerja karyawan, perlu fokus pada peningkatan motivasi dan disiplin kerja. Penting juga memperhatikan kondisi lingkungan kerja seperti penerangan, kelembaban, dan tingkat kebisingan, karena hal tersebut memengaruhi semangat dan hasil kerja karyawan.
Pengaruh Tenaga Kerja, Pelatihan dan Pengalaman terhadap Produktivitas Usaha Tani Padi pada Kelompok Tani Mekar Bangun Setia, Desa Amplas
Authors: Tampubolon Carmelo , Saputra Hendra 
Published: November 2024

Tujuan. Penelitian ini dilakukan untuk mengetahui apakah ada Pengaruh Tenaga Kerja, Pelatihan, Pengalaman Terhadap Produktivitas Usahatanni Padi Pada Kelompok Tani Mekar Bangun Setia, Desa Amplas Kec. Percut Sei Tuan Kab. Deli Serdang
Metode. Penelitian ini menggunakan kuantitatif, Populasi dalam penelitian ini berjumlah 104 Petani. Teknik pengambilan sampel yang digunakan adalah Total Sampling dan diperoleh sampel sebanyak 104 Petani yang telah memenuhi kriteria yang telah di tentukan. Teknik pengumpulan data dalam penelitian dilakukan dengan Uji F, Uji t dan Koefisien determinasi yang sebelumnya data telah di uji menggunakan uji validitas, uji realibilitas dan uji asumsi klasik. Pengolahan data menggunakan program SPSS 25.
Hasil. Hasil penelitian menunjukkan bahwa Tenaga Kerja dan Pelatihan tidak berpengaruh signifikan terhadap Produktivitas Usahatani Sedangkan Pengalaman Berpengaruh Positif dan signifikan terhadap Produktivitas Usahatani. Secara simultan Tenaga Kerja, Pelatihan dan Pengalaman berpengaruh signifikan terhadap Produktivitas Usahatani Koefisien Determinasi yang disesuaikan (adjusted R2) yang berarti Tenaga Kerja, Pelatihan dan Pengalaman mampu memberikan kontribusi terhadap pengaruh Produktivitas semetara sisanya ditentukan oleh variabel-variabel lain diluar model penelitian ini. Hal ini menunjukkan bahwa masih terdapat variabel-variabel lain yang dapat menjelaskan tentang produktivitas.
Implikasi. Dengan adanya pelatihan yang baik, tenaga kerja dalam kelompok tani Mekar dapat mengembangkan keterampilan dan pengetahuan yang diperlukan untuk mengelola usaha tani padi secara efektif. Pengalaman yang diperoleh juga memainkan peran penting dalam meningkatkan kemampuan mereka dalam menghadapi tantangan yang terkait dengan usaha tani. Peningkatan produktivitas ini berpotensi membawa dampak positif, termasuk peningkatan pendapatan dan keberlanjutan usaha tani. Selain itu, pengaruh positif ini juga dapat berperan sebagai contoh inspiratif bagi kelompok tani lainnya dan berkontribusi pada peningkatan pengetahuan dan praktik pertanian di komunitas yang lebih luas.
Pengaruh Pelatihan Kerja dan Motivasi Kerja terhadap Produktivitas Kerja Karyawan Pt. Labquip Indoprima Tangerang
Authors: Rukmana Indra Januar 
Published: November 2024

Tujuan. Penelitian ini bertujuan untuk mengetahui pengaruh Pelatihan kerja terhadap produktivitas kerja, untuk mengetahui pengaruh Motivasi kerja terhadap produktivitas kerja, untuk mengetahui pengaruh pelatihan kerja dan motivasi kerja terhadap produktivitas kerja karyawan.
Metode. Teknik pengambilan sampel menggunakan sampling jenuh dan diperoleh sampel dalam penelitian ini berjumlah 50 responden.
Hasil. pengujian hipotesis penelitian menunjukkan nilai Thitung sebesar 10,701 lebih tinggi dari nilai Ttabel yaitu 2,01174 yang berarti bahwa hipotesis dalam penelitian ini menerima maka H02 ditolak dan Ha2 diterima. pengaruh pelatihan kerja dan motivasi kerja secara bersama-sama terhadap terhadap produktivitas, bahwa nilai Fhitung=84,194 lebih tinggi dari nilai Ftabel yaitu 3,20 yang berarti hipotesis dalam penelitian ini menerima maka H03 ditolak dan Ha3 diterima. Berdasarkan hasil perhitungan uji regresi berganda dapat diketahui persamaan regresi yang terbentuk adalah Y = 9.527 + 0.696 X1 + 0.296 X2 dan berdasarkan koefisien determinasi diketahui bahwa nilai R square sebesar 0.782 atau sebesar 78.2% bahwa nilai tersebut masuk pada kategori sangat kuat. Dengan demikian dapat disimpulkan bahwa “Pengaruh pelatihan kerja dan motivasi kerja terhadap produktivitas kerja karyawan PT. Labquip indoprima Tangerang” diterima.
Implikasi. Sebaiknya perusahaan memberikan pelatihan kerja untuk karyawan baru di awal dan karyawan lama secara berkala agar karyawan lebih kompeten di bidang masing-masing dan kemudian memperhatikan kesejahteraan karyawan yang mana bisa memberikan motivasi dalam bekerja agar produktivitas para karyawa lebih optimal dan mencapai hasil yang maksimal.
Psychometric Analysis of Validity and Reliability of The Indonesian Version of The Modified Fatigue Impact Scale in Chronic Disease Patients
Authors: Rostini Heny , Sofiani Yani , Rayasari Fitrian , Azzam Rohman , Astuti Widya 
Published: November 2024

Fatigue is a lack of physical or mental energy that can be felt by individuals and can disrupt daily activities. Fatigue causes a constant decrease in vitality, a lack of energy, and prevents sleep gaps from being filled, ultimately leading to a decline in productivity and quality of life. The prevalence of fatigue in chronic patients varies, as there is no specific data available. However, the prevalence of fatigue depends on the chronic disease in question, such as chronic kidney disease, diabetes mellitus, and heart disease. To obtain a valid and reliable Indonesian version of the MFIS instrument that can measure fatigue in patients with chronic diseases. The sampling technique used was based on the population, using a non-probability sampling method with purposive sampling. The population in this study consisted of patients with chronic diseases (Diabetes Mellitus, Congestive Heart Failure, Stroke). The population was 244 respondents (4 respondents for language comprehension, 30 respondents for validity and reliability testing, and 210 respondents for the final instrument test). The validity test results, with a sample of (n=210 respondents), showed a loading factor value greater than 0.135, indicating that all MFIS items were valid and highly correlated. The reliability test (n=210 respondents) yielded a Cronbach’s Alpha coefficient of 0.869. This study demonstrates that the Indonesian version of the MFIS instrument is valid and highly correlated. This instrument can be used to identify fatigue in chronic diseases and can serve as a guideline for nurses to implement fatigue interventions, thus helping to reduce and address fatigue issues in patients with chronic diseases.
Health Impact Associated with Pesticides Use among Vegetables Farmers in Nepal: A Secondary Analysis
Authors: Bhattrai Saroj , Dhakal Neelam , Poudyal Anil , Dhimal Meghnath 
Published: November 2024

ackground: The trend of pesticide use in market-oriented vegetables is steadily increasing in Nepal. Farmers in developing countries use hazardous pesticides taking few or no safety measures. This study is aimed to assess health effects of pesticide exposure among vegetable farmers in Nepal.Methods: Analysis of secondary data obtained from Nepal Health Research Council was performed. A cross-sectional study on “Health Effects of pesticide among vegetables farmers and adaptation level of integrated pest management program in Nepal 2013” was conducted by Nepal Health Research Council among 660 farmers in four selected districts of Nepal in 2013/2014. The secondary data obtained were statistically analyzed by student’s‘t’ test, one-way analysis of variance and Pearson correlation statistics. For all tests used, 5% level of significance was considered.Results: Fungicide and insecticides were commonly used pesticides by vegetable farmers in Nepal. Around 51% of the pesticides used were moderately hazardous (II) while, 28% were highly hazardous (Ib). Nearly 12% participants did not use any type of Personal Protective Equipments while spraying pesticides in the field. The prevalence of self-reported poisoning and low Acetylcholinesterase levels among farmers was 51% and 10.3% respectively. Acetylcholinesterase level was found to differ significantly in male as compared to female (P < .05). Conclusions: Almost half of the research participants had self-reported poisoning. Low prevalence of depressed Acetylcholinesterase levels was associated with high use of fungicide compared to organophosphate.Keywords: Acetylcholinesterase; organophosphate; pesticide
Stress and Coping among Caregivers of Differently Able Children
Authors: Sharma Sharada , Subedi Jaya 
Published: November 2024

Background: Caring differently able children can cause stress in the caregivers. They employ a variety of coping mechanisms to deal with stress. The aim of this study is to identify stress and different coping styles among caregivers of differently able children.Methods: A cross-sectional study was carried out in three organizations that accommodated differently abled children. A non-probability purposive sampling technique was used to recruit primary caregivers of children with developmental disabilities. This study examined caregiver stress and different coping styles by using the Parent Stress Scale and Brief COPE Inventory. Face-to-face interviews were used to collect data, which was then analyzed using SPSS.Results: Among the total of 102 caregivers, mothers accounted for 60.8 percent, 57.8 percent child were boys whereas, 49 percent were the child with cerebral palsy. Total mean stress score was 57.17 ±8.808. High level of stress was reported by 58.8 percent of caregivers. Education and family income showed the statistically significant association with stress score P-value<0.05. Total mean coping score was 67.83 ±5.812. Caregivers’ stress had significant positive correlation with different coping styles; active coping, denial, behavioral disengagement, humor, acceptance religion and self-blame (P-value<0.05).Conclusions: More than half of the caregivers had high level of stress. The most frequently used coping styles were self-distraction, acceptance and positive reframing. Caregivers’ stress had significant positive correlation with different coping styles. Therefore, health professionals and service providers should focus on stress reduction and positive coping technique to help family adaptation.Keywords: Caregiver; coping; differently able children; stress.
Day One Drain Amylase as a Predictor of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy
Authors: Pradhan Sumita , Kandel Bishnu , Bhandari Ramesh Singh , Joshi Lakhey Paleswan 
Published: November 2024

Background: Postoperative pancreatic fistula remains the most challenging complication following pancreaticoduodenectomy. As per the definition by the International Study Group on Pancreatic Fistula, post operative pancreatic fistula is diagnosed on or after postoperative day 3. However, several studies have demonstrated that drain fluid amylase on postoperative day 1 may be a better predictor. This study was conducted to determine the diagnostic value of day one drain amylase in predicting the development of post-operative pancreatic fistula.Methods: This was a prospective observational study of patients, who underwent pancreaticoduodenectomy between April 2016 and May 2017. Post operative pancreatic fistula was defined by the International Study Group on Pancreatic Fistula (2005) criteria. The diagnostic value of day one drain amylase was determined by doing a receiver operating curve analysis and compared with the postoperative day 3 value.Results: A total of 49 patients were included. Post operative pancreatic fistula developed in 28 patients (Grade A - 40.8%; B - 12.2%; C - 4.1%). Receiver operating curve analysis confirmed the predictive relationship of day one drain amylase with an area under the curve of 0.79 and kappa 0.5. For clinically relevant postoperative pancreatic fistula, day 3 drain amylase was the better predictor (AUC for DFA3 was 0.73 while AUC for DFA1 was 0.51). A day one drain amylase cut-off value of 350 U/L demonstrated a sensitivity of 75% and specificity of 77.8% with an accuracy of 76.2%. Conclusions: Day one drain amylase predicts postoperative pancreatic fistula in patients following pancreaticoduodenectomy but for clinically relevant postoperative pancreatic fistula, day three drain amylase is a better predictor.Keywords: Amylase; drain fluid amylase; pancreaticoduodenectomy; Pancreatic fistula
Service Readiness for Safe Abortion Services
Authors: Dangol Deeb Shrestha , Gyawali Nisha , Kumar Lal Bibek , Joshi Nisha Kumari , Karki Sujan , Lamichhane Kritee , Phuyal Parash Prasad , Joshi Shipra , Ghimire Jagadishwor , Powell Bill , Dhillon Jina , Lynam Anna 
Published: November 2024

Background: Health service readiness is a prerequisite to accessing quality services. This study analyzes the readiness of health facilities in Nepal to provide comprehensive abortion services by focusing on the availability and quality of care.? Methods: This is a cross-sectional study, and a multi-stage sampling approach was used to select health facilities. A total of 767 health facilities were surveyed from 30 Municipalities across the country. Results: In a study of 767 health facilities surveyed, only 223 (29%) offered abortion services. Among them, 92% offered medical abortion, 48% provided manual vacuum aspiration, 18% offered dilation and evacuation and 18% offered medical induction. Approximately 7% of health facilities lacked trained providers yet still provided services and 29% of health facilities providing abortion services were not compliant with legal requirements. Interestingly, 13% of these facilities lacked short-acting contraceptives. Conclusions: Most health facilities in Nepal lack readiness for Safe Abortion Services (SAS), failing to meet minimum criteria, including to provide abortion legally. Urgent collaborative efforts among policymakers, administrators, and healthcare providers are needed to align with Nepal's Sustainable Development Goals and address gaps in safe abortion service availability. This includes policy updates, strengthening Public-Private Partnerships (PPPs), and ensuring comprehensive SAS implementation and financing as part of essential health services.Keywords: Health facility; listed facility; post abortion care; safe abortion; service readiness.
Analisis kebugaran jasmani pada peserta didik kelas X1 di SMA negeri 7 Bengkulu selatan
Authors: Putra Tedy Angga , Nopiyanto Yahya Eko , Sutisyana Ari , Syafrial  , Rizky Oddie Barnanda 
Published: November 2024

Tujuan dari penelitian ini adalah untuk mengetahui tingkat kebugaran fisik siswa di SMA Negeri 7 Bengkulu Selatan. Penelitian deskriptif kuantitatif adalah proses pencarian pengetahuan dengan data. Penelitian ini mencakup semua siswa di SMA Negeri 7 Bengkulu Selatan, yang berjumlah 805 siswa. Dalam penelitian ini, jumlah sampel adalah 20 orang, 10 laki-laki dan 10 perempuan, karena metode sampel rekomendasi digunakan. Penelitian ini menggunakan instrumen TKJI, yang terdiri dari lari 60 meter, angkat tubuh (60 detik pa), baring duduk 60 detik, loncat tegak, dan tes jarak jauh (1.200 m pa dan 1.000 m pi). Hasil tes kebugaran jasmani dari lima item di SMA Negeri 7 Bengkulu Selatan, yaitu keterampilan lari 60 meter, diklasifikasikan sebagai berikut: pada laki-laki, kurang 10% (1 peserta didik), sedang 30% (3 peserta didik), dan baik 60 (6 peserta didik). Pada perempuan, kurang 20% (2 peserta didik), sedang 60% (6 peserta didik), dan baik 20% (2 peserta didik). Tes Loncat Tegak pada laki-laki kurang dari 10% (1 peserta didik), kurang dari 40% (4 peserta didik), dan kurang dari 50% (5 peserta didik). Tes Lari 1.200 Meter pada laki-laki kurang dari 30% (3 peserta didik), kurang dari 40% (4 peserta didik), dan kurang dari 50% (5 peserta didik). Pada perempuan kurang dari 40% (4 peserta didik). tes TKJI yang mencakup lima item menunjukkan bahwa dua belas siswa dan siswi, atau 60%, lebih kebugaran jasmani setelah melakukannya.
Abstract
This study is to find out the level of physical fitness of students at SMA Negeri 7 South Bengkulu. Quantitative descriptiveresearch is the process of searching for knowledge with data. This study included all students at SMA Negeri 7 South Bengkulu,which totaled 805 students. In this study, the number of samples was 20 people, 10 men and 10 women, because the recommendedsample method was used. This study uses TKJI instruments, which consist of running 60 meters, lifting (60 seconds pa), lyingdown for 60 seconds, jumping upright, and long-distance tests (1,200 m pa and 1,000 m pi). The results of the physical fitness testof five items at SMA Negeri 7 South Bengkulu, namely the 60-meter running skill, are classified as follows: in men, less than 10%(1 student), medium 30% (3 students), and good 60 (6 students). In women, less than 20% (2 students), medium 60% (6 students),and good 20% (2 students). The Upright Jump Test in males was less than 10% (1 student), less than 40% (4 students), and lessthan 50% (5 students). The 1,200 Meter Running Test in males was less than 30% (3 students), less than 40% (4 students), and lessthan 50% (5 students). In women, less than 40% (4 students). The five-item TKJI test showed that twelve students, or 60%, weremore physically fit after doing so.