bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social participation and depression among resettled Syrian refugees: examining a moderated mediation of social support and bonding or bridging social capital
Authors: Johnson-Singh Charisse M. , Sengoelge Mathilde , Engström Karin , Saboonchi Fredrik 
Published: October 2024

IntroductionAspects of social capital, including social participation and social support, are among the factors influencing refugee mental health after resettlement. However, the mechanisms by which these aspects interact with one another and affect mental health remain unclear. This study investigates whether social participation influences depressive symptoms via social support and whether this influence is more prominent for Syrian refugees participating primarily in coethnic (bonding) networks compared to cross-ethnic (bridging) networks during the early stages of resettlement.MethodsUsing data from a cohort of 464 Syrian refugees recently resettled in Sweden, a moderated mediation analysis was conducted with multigroup structural equation modelling to investigate the mediatory role of social support in the association between social participation and depressive symptoms as well as the moderating role of bonding networks (social participation with other Syrians) versus bridging networks (social participation with Swedes) in this relationship.ResultsFrequent social participation, compared to rare or no participation, was significantly associated with lower depressive symptoms, regardless of whether participation included a broad or limited range of activities. Social support only mediated this relationship for those with primarily bonding networks, indicating that the mediation itself was moderated by network type. While participating in both bridging and bonding networks was associated with lower depressive symptoms, bonding networks amplified the effect of social participation on depressive symptoms via increased social support, resulting in an overall twofold decrease in depressive symptoms compared to those with bridging networks.DiscussionThese findings indicate that the frequency of social participation may be a more important consideration for fostering mental well-being in recently resettled refugees than the specific types of activities. Furthermore, while both bonding and bridging social networks confer mental health benefits, access to coethnic networks in early resettlement appears to provide a particularly crucial source of social support.
Including highly educated migrants in academia to improve their health—protocol for a pilot intervention
Authors: Ahmed Khadra Yasien , Fadnes Lars T. , Kumar Bernadette , Hasha Wegdan , Diaz Esperanza 
Published: October 2024

IntroductionNorway’s healthcare system needs a diversified work force to meet societal demands for improved cultural competence. However, many migrants in Norway who were educated as health professions in their home countries are not practicing these professions. This may negatively affect their physical and mental health and hinder their personal social integration. Though good health is often seen as a precondition for work, relevant working activities can also improve health. However, including health professionals with foreign education in academic institutions prior to receiving necessary accreditation is a complex task. This study will pilot an intervention aiming to improve health through meaningful integration of these professionals in academic environments.Materials and methodsThis paper is a protocol for a non-randomized pilot intervention study targeting migrants who are waiting for their health education accreditation in Norway. To test the benefits of meaningful activity on health and explore possibilities for implementing such activity, we have designed a six-month long intervention consisting of including nurses, doctors, and other highly educated migrants with healthcare backgrounds between 20 and 67 years of age, into health-related working tasks, at two higher education institutions in Bergen, Norway. The intervention will be tailored according to the participant’s expertise. This hybrid type 2 pilot protocol paper will present how feasibility, fidelity, dose received (satisfaction), and dose of exposure (participation), will be assessed and whether the intervention is experienced as beneficial for the participants’ health as primary outcome utilizing both quantitative and qualitative methods.ConclusionWe present a complex, personalized intervention that has the potential for large scale implementation in the future. By thoroughly presenting our designed intervention and assessment methods, this protocol will add to the study’s transparency and facilitate replicability and comparison with future studies. This study will be of benefit to the migrants themselves, policy makers, government agencies and academia at large as it can point to a unique and sustainable way of speeding up the integration of highly educated migrants in their respective fields in a new host country.
Impact of land-use change on coupling coordination degree of regional water–food–carbon system
Authors: Zhao Li , Yu Jie , Song Xinming , Niu Yichun , Xie Jiaxi , Zhang Lizhu , Li Xiaoqing 
Published: October 2024

IntroductionThe objective of this study is to investigate the impact of land use changes on the coupling coordination of the regional water-food-carbon system in Hebei Province. Moreover, the findings aim to offer insights for achieving comprehensive and coordinated development of regional resources.MethodsBy constructing an evaluation index system of the coupled coordinated development of the water-food-carbon system, using the coupled coordination model to study the coupled coordination of the water-food-carbon (WFC) system in Hebei Province from 2010 to 2020, and applying the Pearson correlation coefficient and ArcGIS to analyze the impacts of land-use changes on the degree of coupled coordination.ResultsThe results show that: (1) The most notable characteristics of land type changes include a decrease in cropland and an increase in construction land, primarily driven by the conversion of cropland to construction sites. The total area converted amounts to 8207.20 km2. (2) The degree of coupled coordination of the water-food-carbon system in the study area as a whole shows an upward and then downward trend, and shows a spatial distribution pattern of “high in the north-east and low in the south-west”; (3) In Hebei Province, the degree of coupling coordination within the water-food-carbon system exhibits a stable positive correlation with forest land, grassland, and water area. Additionally, the transfer of forest land and grassland are significant factors influencing the delineation of cold and hot spots within the region.DiscussionTherefore, in addressing the coordinated development of the water-food-carbon system, it is essential to consider the influence of land. Resources should be allocated judiciously based on regional advantages to promote sustainable development effectively.
Caretaker-reported quality of life, functionality, and complications associated with assistive mobility cart use in companion animals
Authors: Narum Melissa , Miscioscia Erin , Repac Jennifer 
Published: October 2024

ObjectiveTo evaluate the impact of assistive mobility carts on companion animals and caretakers’ quality of life by investigating factors pertaining to caretaker satisfaction, the ability to perform daily tasks, and complication rates.Materials and methodsA 23-question survey was distributed to caretakers of animals using carts to evaluate the animal and caretakers’ quality of life, acceptance, ability to complete functional tasks, and complications. Data from canine, feline, and rabbit responses were analyzed separately.ResultsDogs and cats had improved quality of life in 62 and 57% of responses and 61 and 60% for their caretakers, respectively. There was no improvement in the quality of life of rabbits or their caretakers. Regarding the complication rate, 64% were reported to have at least one complication associated with cart use, 53% of which were wounds. Across all species, there was a reported improvement in ability to perform daily tasks and activities.Conclusions and clinical relevanceCaretakers reported that assistive mobility carts improve both companion animals’ and caretakers’ quality of life, despite high prevalence of complications, including wounds. Future studies exploring specific disease conditions and long-term outcomes will be useful for guiding clinical recommendations.
Bioactivity-Guided Isolation of Secondary Metabolites from Camellia fascicularis: Antioxidative Antibacterial Activities and Anti-Inflammatory Hypoglycemic Molecular Docking
Authors: Tang Jiandong , Li Jingjing , Wu Boxiao , Li Ruonan , Tang Junrong , Kan Huan , Zhao Ping , Zhang Yingjun , Wang Weihua , Liu Yun 
Published: October 2024

Camellia fascicularis is a valuable ornamental, edible, and medicinal plant with promising prospects for bioactivity development. We screened the bioactivity of eight fractions (Fr. A−I) obtained from the ethyl acetate phase of C. fascicularis via silica gel column chromatography. The results indicated that the anti-inflammatory, antioxidative, and antimicrobial active components were mainly found in Fr. B*, E, A, and H; Fr. A–G; and Fr. D–I, respectively. Bioactivity-guided isolation identified 18 secondary metabolites. Compounds 1, 3–5, 7, and 15–18 were isolated from the genus Camellia for the first time in this study, whereas the other compounds were also isolated from this plant for the first time. The structures of these compounds were elucidated through comprehensive spectroscopic techniques. Compounds 1, 9−11, 28, 30, and 31 demonstrated antioxidative activities comparable to those of ascorbic acid, whereas the remaining compounds exhibited diminished antioxidative activity. In terms of antimicrobial activity, compounds 7, 18, 22, and 27 exerted inhibitory potency against Pseudomonas aeruginosa, similar to tetracycline (MIC: 125 µg/mL). Other compounds showed moderate to weak inhibitory effects against Staphylococcus aureus and Escherichia coli (MIC: 250–500 µg/mL). Molecular docking revealed that compounds 2, 36, 41, and 65 showed strong binding affinity for 8ET0, whereas compounds 2, 36, 38, 40, 63, and 65 showed strong binding affinity for 3A4A. This research further increased the diversity of the secondary metabolites of C. fascicularis, laying a foundation for the subsequent development and utilization of this species.
Fungi Associated with Olive Tree (cv. ‘Nocellara del Belice’) Decay in Trapani Province (Sicily, Italy)
Authors: Lamendola Marika , Mirabile Giulia , Muratore Josè , Torta Livio 
Published: October 2024

Recently, in several locations in the province of Trapani (Sicily, Italy), olive growers have reported cases of decaying olive trees of cv. ‘Nocellara del Belice’, showing symptoms of defoliation, branch drying, xylem browning, and reduced production. Internal symptoms include white and brown wood rot, starting from the base of the trunk. These alterations have been observed in trees irrigated using a pipe system at the trunk with spray sprinklers. To identify the causal agents of decay, some trees were eradicated and dissected, and woody samples were processed to isolate and identify the associated fungal micro-organisms. The most common colonies were identified using morphological (macro- and microscopical observation) and molecular (PCR amplification of the rDNA-ITS region) analyses. Nine fungal taxa were identified, of which four were associated with this decay syndrome (Coriolopsis gallica, Fomitiporia mediterranea, Kirschsteiniothelia sp., and Pleurostoma richardsiae), three were considered ubiquitous and opportunistic fungi (Alternaria spp., Aspergillus amstelodami, and Trichoderma sp.), and the other two were mycelia sterilia. Artificial inoculation satisfied Koch’s postulates, confirming the pathogenicity of the aforementioned fungi, even though the infections in the fields seem to be related to the irrigation system. This hypothesis would seem to be confirmed by the progression of decay over time in the trees subjected to the irrigation system described but not reported in olive groves differently managed. It is therefore considered appropriate to conduct further and more in-depth investigations aimed at studying the correlation between the irrigation system, presence of fungal agents, and manifestation of the syndrome. A further ongoing investigation is aimed at the use of biostimulants (Agrusaver, Savory Sun, VA LLC) on symptomatic trees, with the aim of both improving the vegetative performance of the host and limiting the symptoms detected in the field.
Chemical Composition and Bioactivity Dataset Integration to Identify Antiproliferative Compounds in Phyllanthus Plants
Authors: Diaz Luis , Díaz-Herrera Taylor H. , Coy-Barrera Ericsson 
Published: October 2024

Background/Objectives: Phyllanthus species are renowned in traditional medicine for their diverse therapeutic properties, including potential anticancer activities. This study explored the antiproliferative potential of six Phyllanthus species by integrating chemical composition with bioactivity assays to identify key antiproliferative compounds. Methods: The integration of liquid chromatography–mass spectrometry (LC-MS)-based chemical composition data with antiproliferative activity against three cancer cell lines—PC-3 (prostate adenocarcinoma), SiHa (cervical carcinoma), and A549 (lung carcinoma)—as well as a normal mouse fibroblast line (L929) was performed by covariate analysis. These compounds were subsequently isolated and structurally characterized using spectroscopic methods. Results: Through covariate statistics, seven m/z features were found to be plausible active compounds, and after isolation, they were related to butyrolactone and arylnaphthalide lignans. Among the active isolates, an unreported compound, (+)-phyllanlathyrin 6, was discovered in the aerial part of Phyllanthus lathyroides. The isolated compounds exhibited moderate to good antiproliferative activity (IC50 < 20 µM) with selectivity to SiHa, validating the covariate-based identification approach. Conclusions: These findings highlight the potential of Phyllanthus species as sources of novel anticancer agents, with specific arylnaphthalide lignans showing promising cytotoxic effects that could be further developed into therapeutic leads. Additionally, this study underscores the value of combining advanced analytical techniques with bioactivity testing to uncover bioactive compounds from natural sources. The results contribute to the growing body of evidence supporting the therapeutic relevance of Phyllanthus species and provide a foundation for future drug development efforts targeting cancer treatment.
Photosynthetic Electron Flows and Networks of Metabolite Trafficking to Sustain Metabolism in Photosynthetic Systems
Authors: Fakhimi Neda , Grossman Arthur R. 
Published: October 2024

Photosynthetic eukaryotes have metabolic pathways that occur in distinct subcellular compartments. However, because metabolites synthesized in one compartment, including fixed carbon compounds and reductant generated by photosynthetic electron flows, may be integral to processes in other compartments, the cells must efficiently move metabolites among the different compartments. This review examines the various photosynthetic electron flows used to generate ATP and fixed carbon and the trafficking of metabolites in the green alga Chlamydomomas reinhardtii; information on other algae and plants is provided to add depth and nuance to the discussion. We emphasized the trafficking of metabolites across the envelope membranes of the two energy powerhouse organelles of the cell, the chloroplast and mitochondrion, the nature and roles of the major mobile metabolites that move among these compartments, and the specific or presumed transporters involved in that trafficking. These transporters include sugar-phosphate (sugar-P)/inorganic phosphate (Pi) transporters and dicarboxylate transporters, although, in many cases, we know little about the substrate specificities of these transporters, how their activities are regulated/coordinated, compensatory responses among transporters when specific transporters are compromised, associations between transporters and other cellular proteins, and the possibilities for forming specific ‘megacomplexes’ involving interactions between enzymes of central metabolism with specific transport proteins. Finally, we discuss metabolite trafficking associated with specific biological processes that occur under various environmental conditions to help to maintain the cell’s fitness. These processes include C4 metabolism in plants and the carbon concentrating mechanism, photorespiration, and fermentation metabolism in algae.
Empirical Study on Delays in Highway Projects: A Comparative Analysis of Small and Large Projects
Authors: Kumar Modish , Kumari Santosh 
Published: October 2024

Delays in National Highway projects, regardless of their geographical location, have exerted a substantial impact on project performance and yielded unfavourable economic consequences. The majority of these projects in India are implemented by Public-Private Partnerships (PPPs), which use a wide range of contract types, including traditional ones such as item rate contracts and bills of quantity, in addition to more modern alternatives such as build operate transfer, engineering procurement and transfer, and recently developed hybrid models. This study examines and compares the reasons of critical delays in national highway projects in Himachal Pradesh with project characteristics. This mixed-methods study gathered comprehensive data from project participants using qualitative analysis and a survey questionnaire. Interviews and document analysis identified delay factors, which were then assessed through a structured questionnaire distributed to a representative sample of project participants. The findings highlight critical delay factors in National Highway projects in Himachal Pradesh and offer insights into the unique challenges faced by large PPP projects and small traditional projects. Despite the small sample size of 134 survey responses, the findings are significant but may have limited applicability to other infrastructure projects due to socio-economic and geographic variations. This suggests a research gap indicating that further analysis is needed to understand the challenges in EPC and PPPs for large hilly road projects, along with a focused study on organizational culture to assess highway project performance. This study contributes empirical data to the literature about the steep National Highway projects in Himachal Pradesh. Policymakers, project specialists, and stakeholders may ascertain the reasons of delays and formulate targeted actions to enhance project efficiency.
Analyzing the Impact of Executive Excess Compensation on Organizational Technological Innovation: Evidence from Bangladesh Pharmaceuticals & Chemicals Industry
Authors: Islam Sumaiya , Rahim Md. Abdur , Akter Rito Maksuda , Mim Sara Islam , Rahman Rahat 
Published: October 2024

This study analysing the impact of executive excess compensation (EEC) that is influencing the quality and efficiency of Organizational Technological Innovation (OTI). Using the Agency Theory, the Resource-Based View (RBV) and Upper Echelons Theory perspective in this study, the study has identified the compatibility of Executive Excess Compensation (EEC) with Organizational Technological Innovation (OTI) and then it has focused on investigation of the relationship between Executive Excess Compensation (EEC) with Organizational Technological Innovation (OTI) and for this quantitative analysis has been done by the usage of a structural equation modelling (SEM) approach by the usage of SmartPLS software. The findings regarding the compatibility of EEC with OTI suggest even a strong alignment between the executive compensation levels and the organization’s innovation capabilities. This indicates that companies offering the executive excess compensation which tend to demonstrate greater innovation efforts that is potentially driven by incentives linked to the compensation structures. Further, the analysis has revealed that higher levels of EEC were consistently associated with the overall greater technological innovation efficiency and to the technological innovation quality which is indicating on a robust relationship between executive pay and innovation performance. The results of this study ultimately provide empirical support for the notion that executive compensation plays a crucial role in case of driving innovation initiatives within organizations which is particularly in the pharmaceutical and chemical sectors of Bangladesh. The findings of the study can give insights for researchers, industry practitioners, policymakers, investors and for academics. However, the study is with some limitation and by acknowledging that further research is definitely needed to explore on the potential areas of improvement on this untapped or unique field.
MEMPERKENALKAN KEMBALI OLAHRAGA TRADISIONAL GOBAK TERHADAP MINAT MAHASISWA S-1 FARMASI UNSIKA
Authors: Lukman Alvian Fuad , Maulana Deni , Pahlevi Reza , Rahul Pardede , Dewi R. Retna Kinanti , Izzuddin Deden Akbar 
Published: October 2024

Dalam permainan klasik gobak sodor, tim bersaing dengan mencegah lawan mereka melewati setiap garis. Konsep permainan tradisional menunjukkan bahwa permainan tradisional gobak sodor memiliki komponen sikap sosial. Permainan ini dapat dimainkan oleh dua tim, yaitu penjaga dan penyerang, dengan masing-masing tim terdiri dari 4-6 orang. Pengabdian Kepada Masyarakat di lakukan di daerah Teluk Jambe, Karawang Universitas Singaperbangsa Karawang, dengan populasi 21 orang menghasilkan 9 dari 21 orang yang kurang paham dengan permainan gobak sodor. Metode yang digunakan dalam pengabdian masyarakat ini artinya metode sosialisasi dalam bentuk permainan. Metode permainan ialah alat pengajaran yg diimplementasikan dalam permainan. Setelah sosialisasi yang dilakukan terhadap , Mahasiswa Farmasi Angkatan 2019 banyak yang sudah lupa bahkan ada yang tidak tahu mengenai permainan tradisional Gobak Sodor
Effects of Li concentration in the precursor solution on NiO thin films deposited using electrostatic spray deposition
Authors: Okubo Keito , Sugiyama Mutsumi 
Published: October 2024

Abstract
Undoped and Li-added NiO thin films were deposited using electrostatic spray deposition (ESD) techniques. Initially, the NiO thin films displayed minimal contamination, predominantly C and H. The NiO thin films exhibited a flat surface morphology comprising grains of uniform size, approximately 20–30 nm in diameter, and reliable crystal growth, with a full width at half maximum of approximately 0.30 in X-ray diffraction analysis. Moreover, the NiO/ZnO diode demonstrated superior properties when a 5 at% Li concentration solution was incorporated. The rectification ratio reached approximately 2.3 × 103 at ±1.0 V, with an ideality factor of 1.9. Additionally, the NiO/ZnO diodes exhibited remarkable photovoltaic properties even without detailed optimization. These findings underscore the potential of ESD in advancing semiconductor thin-film technology, thereby paving the way for more cost-effective and scalable production methods.