bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance of quantitative immunochemical test for fecal hemoglobin for surveillance of colorectal neoplasia after polypectomy in clinical practice
Authors: Yang Hsin‐Yeh , Lin Yu‐Min , Chong Lee‐Won , Chang Hung‐Chuen , Liao Chao‐Sheng , Yang Kuo‐Ching 
Published: October 2018

SummaryAimsWe examined the yield of immunochemical test for fecal hemoglobin (FIT) for the post‐polypectomy individuals in a colorectal cancer screening program.MethodsWe enrolled 50‐75 years average‐risk individuals who attended a biennial FIT‐based colorectal cancer screening program from March 2010 to December 2011 (index round) and from January 2012 to December 2013 (repeated round). Colonoscopy was recommended to the participants with an FIT ≧ 30 μg Hb/g feces.Participants identified with adenomas and removed by polypectomy in the index round were defined as surveillance group (Sur‐G). Participants with an FIT < 30 μg Hb/g feces in the index round or identified as non‐neoplastic findings of the indexed colonoscopy were defined as repeated screening group (Rsc‐G). We compared key quality indicators for FIT and colonoscopy between Sur‐G and Rsc‐G according to the findings of the repeated round. A p < 0.05 determined by chi‐square test was defined as significant.ResultsThere were 222 post‐polypectomy surveillance (Sur‐G) and 7311 repeated screening individuals (Rsc‐G) enrolled for analysis. The FIT positivity rate, colonoscopy compliance rate and colorectal neoplasia (CRN) detection rate were 504 of 7311 (6.9%) vs. 46 of 222 (20.7%) (p < 0.001); 381 of 504 (75.6%) vs. 44 of 46 (95.7%) (p < 0.001) and 207 of 504 (41.1%) vs. 32 of 46 (69.6%) (p < 0.001) for Rsc‐G and Sur‐G respectively. The FIT positivity rate, colonoscopy compliance rate and CRN detection rate were significantly higher in the Sur‐G.ConclusionsOur results suggest individuals after polypectomy still had high risk of CRN. Biennial FIT may play a role for post‐polypectomy surveillance. Subsequent prospective study is necessary to evaluate the effectiveness of FIT for post‐polypectomy surveillance.Copyright © 2017, The Gastroenterological Society of Taiwan, The Digestive Endoscopy Society of Taiwan and Taiwan Association for the Study of the Liver.
Unusual subcutaneous and choroidal metastases from esophageal squamous cell carcinoma denote a poor prognosis: A case report and literature review
Authors: Kuo Shin‐Huei , Yu Fang‐Jung , Shih Hsiang‐Yao , Kuo Hsi‐Kung , Wu Chun‐Chieh , Lee Po‐Yen , Wu I‐Chen 
Published: October 2018

SummaryEsophageal squamous cell carcinoma (ESCC) is a devastating disease, generally diagnosed at an advanced stage. Skin metastasis is rare, and choroidal metastases are extremely rare. Herein, we report a case of a 47‐year‐old habitual smoker and drinker who presented with progressive dysphagia, weight loss, and multiple enlarged tumors over his trunk and limbs for 3 months. Upper endoscopy revealed an ulcerative esophageal mass, and pathology confirmed moderately differentiated SCC. Fluorodeoxyglucose‐positron emission tomography/computed tomography revealed high uptake in the esophageal mass, bone, and subcutaneous lesions. Incisional biopsy of the right thigh tumor indicated metastatic SCC. Accordingly, the patient received palliative chemotherapy and mediastinal radiotherapy. Two weeks later, he experienced partial right visual field loss. Imaging findings suggested choroidal metastasis. Although the skin lesions shrank after treatment, the patient's health quickly deteriorated and he died of severe pneumonia 3 months later. To our knowledge, this is the first report of ESCC with simultaneous subcutaneous and ocular metastasis. Cutaneous and ocular metastases secondary to ESCC are extremely rare; both suggest cancer dissemination and imply an ominous prognosis. Careful physical examination and high awareness are required during follow‐up.Copyright © 2017, The Gastroenterological Society of Taiwan, The Digestive Endoscopy Society of Taiwan and Taiwan Association for the Study of the Liver.
Timing for cranioplasty to improve neurological outcome: A systematic review
Authors: De Cola Maria C. , Corallo Francesco , Pria Deborah , Lo Buono Viviana , Calabrò Rocco S. 
Published: October 2018

AbstractIntroductionCranioplasty is a surgical technique applied for the reconstruction of the skullcap removed during decompressive craniectomy (DC). Cranioplasty improves rehabilitation from a motor and cognitive perspective. However, it may increase the possibility of postoperative complications, such as seizures and infections. Timing of cranioplasty is therefore crucial even though literature is controversial. In this study, we compared motor and cognitive effects of early cranioplasty after DC and assess the optimal timing to perform it.MethodsA literature research was conducted in PubMed, Web of Science, and Cochrane Library databases. We selected studies including at least one of the following test: Mini‐Mental State Examination, Rey Auditory Verbal Learning Test immediate and 30‐min delayed recall, Digit Span Test, Glasgow Coma Scale, Glasgow Outcome Scale, Coma Recovery Scale‐Revised, Level of Cognitive Functioning Scale, Functional Independence Measure, and Barthel Index.ResultsSix articles and two systematic reviews were included in the present study. Analysis of changes in pre‐ and postcranioplasty scores showed that an early procedure (within 90 days from decompressive craniectomy) is more effective in improving motor functions (standardized mean difference [SMD] = 0.51 [0.05; 0.97], p‐value = 0.03), whereas an early procedure did not significantly improve neither MMSE score (SMD = 0.06 [−0.49; 0.61], p‐value = 0.83) nor memory functions (SMD = −0.63 [−0.97; −0.28], p‐value < 0.001). No statistical significance emerged when we compared studies according to the timing from DC.ConclusionsIt is believed that cranioplasty performed from 3 to 6 months after DC may significantly improve both motor and cognitive recovery.
Determinants of mobile technology use and smartphone application interest in cancer patients
Authors: Raghunathan Nirupa Jaya , Korenstein Deborah , Li Qing S. , Tonorezos Emily S. , Mao Jun J. 
Published: October 2018

AbstractBackgroundSupportive care is a critical component of the treatment of cancer patients that is underutilized; patient lack of information about these services is an important barrier. Mobile technologies may be useful tools for delivering information, but cancer patient use of and interest in using them to learn about supportive care services have not been described. This study evaluates factors associated with cancer patient use of mobile technologies and interest in smartphone applications for information delivery about supportive care.MethodsWe conducted a cross‐sectional survey among cancer patients from one urban academic hospital and 11 community hospitals. Patients self‐reported use of mobile technologies and interest in smartphone applications. Multivariate logistic analysis was used to identify determinants of mobile technology use and smartphone interest.ResultsAmong 631 participants, 466 (74%) reported regular use of mobile devices and 242 (39%) expressed an interest in supportive care information via smartphone applications. Patients under 45 were more likely to use a mobile device (Adjusted Odds Ratio [AOR] 6.8, 2.8‐16.9 95% CI, P < 0.001) and were interested in smartphone applications for delivery of information (AOR 3.2, 1.8‐5.9 95% CI, P < 0.001). Non‐white patients had similar use of mobile technology compared to whites but reported greater interest in smartphone application‐based information (AOR 3.4, 2.1‐5.5 95% CI, P < 0.001).ConclusionMany patients expressed interest in smartphone application‐based information about supportive care services, especially those who are younger and non‐white. Future studies should investigate the characteristics of patients and smartphones applications that will optimize information delivery through a mobile technology platform.
Downregulated miR‐144‐3p contributes to progression of lung adenocarcinoma through elevating the expression of EZH2
Authors: Liu Chao , Yang Zuozhang , Deng Zhiyong , Zhou Youjun , Gong Quan , Zhao Ruilian , Chen Ting 
Published: October 2018

AbstractObjectivesThe intention of our study was to investigate the relationship between miR‐144‐3p and EZH2 as well as the effects of their interaction on cell propagation and invasiveness in lung adenocarcinoma (LUAD).MethodsThe expression levels of miR‐144‐3p and EZH2 in LUAD tissues and normal tissues were determined by qRT‐PCR. The dual‐luciferase reporter assay was utilized to validate the targeting relationship between miR‐144‐3p and EZH2. MTT assay and colony formation assay were performed to evaluate the viability and propagation of LUAD cells, while the effects of miR‐144‐3p and EZH2 on LUAD cell invasiveness were confirmed by transwell assay. Protein expression levels of VEGFA, MMP2, and MMP9 were measured by Western blot. Furthermore, xenograft tumor models were established to verify the effects of miR‐144‐3p on tumor formation and EZH2, VEGFA, MMP2 and MMP9 expressions in vivo.ResultsmiR‐144‐3P was downregulated in LUAD tissues, and overexpression of miR‐144‐3p inhibited propagation and invasiveness of LUAD cells. EZH2 was a target of miR‐144‐3p and was highly expressed in LUAD cells. Knockdown of EZH2 could suppress the propagation and invasion of LUAD cells. Increased miR‐144‐3p expression exerted an inhibitory effect on LUAD tumor formation in vivo.ConclusionOverexpression of miR‐144‐3p impeded the propagation and invasiveness of LUAD cells by targeting EZH2.
Angiographic and clinical outcomes of antegrade versus retrograde techniques for chronic total occlusion revascularizations: Insights from the PRISON IV trial
Authors: Zivelonghi Carlo , van Andel Mitzi , Venturi Gabriele , Amoroso Giovanni , Teeuwen Koen , Tijssen Jan G.P. , Tavella Domenico , Ribichini Flavio , ten Berg Jurrien M. , Resning Benno J. , Henriques José P.S. , Suttorp Maarten J. , Agostoni Pierfrancesco , Van der Schaaf Renè J. 
Published: October 2018

AbstractObjectivesAvailable data indicate mixed outcomes after using retrograde techniques for chronic total occlusion(CTO) recanalization, with generally higher need for repeat revascularization. Aim of this study is to analyze the angiographic and clinical outcome of patients treated with retrograde techniques in the PRISON‐IV trial.Methods and ResultsThis is a post‐hoc sub‐analysis from the randomized PRISON‐IV trial. Briefly, 330 patients with a successfully recanalized CTO lesion were randomized 1:1 to receive either hybrid‐SES or EES. The hybrid‐SES failed to reach the non‐inferiority primary endpoint of in‐segment late lumen loss at 9‐month angiography follow‐up. In the present analysis, we divided the population according to the first technical approach, namely antegrade (n = 285) or retrograde approach (n = 45). Demographic characteristics were similar between the two groups, while angiographic features disclosed higher CTO lesion complexity in the group treated with retrograde techniques (J‐CTO score: 1.8 ± 1.1 vs 2.6 ± 1.1, respectively, P < 0.001), with longer occlusions (17.6 ± 10 mm vs 28.8 ± 18.7 mm, P < 0.001) and longer stented segment (48.9 ± 24.4 mm vs 73.1 ± 33.2 mm, P < 0.001). Quantitative coronary analysis disclosed similar results at follow‐up angiography, with a non‐significantly higher in‐stent late‐lumen loss in the retrograde group (0.08 ± 0.52 mm vs 0.18 ± 0.56 mm, P = 0.32). Clinical follow‐up at 12‐months showed similar outcome, with a non‐significantly higher target‐lesions revascularization rate in the retrograde group (6% vs 11.1% respectively, P = 0.2). Significant improvements in angina functional class were observed in both groups.ConclusionsThe present analysis supports the benefits of retrograde techniques in CTO revascularization, with non‐significant differences in angiographic and clinical outcomes at late follow‐up.
Favorable neurological outcome after ischemic cerebrovascular events in patients treated with percutaneous left atrial appendage occlusion compared with warfarin
Authors: Lee Oh‐Hyun , Kim Young Dae , Kim Jung‐Sun , Pak Hui‐Nam , Hong Geu‐Ru , Shim Chi Young , Uhm Jae‐Sun , Cho In‐Jeong , Joung Boyoung , Hong Sung‐Jin , Ahn Chul‐Min , Kim Byeong‐Keuk , Ko Young‐Guk , Choi Donghoon , Hong Myeong‐Ki , Yu Cheol‐Woong , Lee Hyun‐Jong , Kang Woong‐Chol , Shin Eun‐Seok , Choi Rak‐kyeong , Lim Do‐Sun , Freixa Xavier , Tzikas Apostolos , Heo Ji Hoe , Jang Yangsoo , Park Jai‐Wun 
Published: October 2018

AbstractObjectivesThis study sought to investigate neurological disability after ischemic cerebrovascular events in patients treated with left atrial appendage (LAA) occlusion compared with those on warfarin.BackgroundPrior studies demonstrated that cerebrovascular events after LAA occlusion in patients with nonvalvular atrial fibrillation (NVAF) is largely nondisabling.MethodsFrom the 1,189 patients in the Korean LAA Occlusion and European Amplatzer Cardiac Plug Multi‐Center Registry, 24 patients who experienced ischemic cerebrovascular events after LAA occlusion were enrolled. The neurological outcomes were compared with those in 68 patients who experienced an ischemic cerebrovascular event while on warfarin (Yonsei Stroke Registry). A modified Rankin scale (mRS) score of 3–6 categorized the cerebrovascular event as disabling. The mRS at discharge and at 3 and 12 months postcerebrovascular event in the two groups was compared.ResultsThe percentages of disabling cerebrovascular events were 37.5% and 58.8% at discharge (P = 0.07), 20.8% and 42.6% at 3 months (P = 0.08), and 12.5% and 39.7% at 12 months (P = 0.02) in the LAA occlusion and warfarin groups, respectively. The mRS was significantly lower in the LAA occlusion group at discharge and at 3 months (P < 0.01) and 12 months (P < 0.01) postcerebrovascular event despite no significant difference in mRS before cerebrovascular events (P = 0.98). Patients in the LAA occlusion group demonstrated a significant reduction in mRS between discharge and 12 months (P < 0.01), unlike patients in the warfarin group (P = 0.10).ConclusionsIschemic cerebrovascular events in patients who previously underwent percutaneous LAA occlusion for NVAF were more favorable than in patients on warfarin.
Impacts of porous material fluid bulk properties on noise attenuation performance of cylinder shell structure based on finite element model
Authors: Li Bin , Li Jian , Yan Shilin , Ju Linfeng , He Xu 
Published: October 2018

SummaryThe noise control method of laying acoustic blanket is adopted to construct a cylinder cell noise experimental device; a typical porous material, melamine foam (MF), is used for noise attenuation experiments in aluminum (Al) and aluminum/melamine foam (Al/MF) cylinder shells and to achieve corresponding in‐shell noise response spectrograms. Based on the Virtual Lab acoustics software, a finite element model has established for the analysis of noise in the Al/MF cylinder shell and numerical simulation computation has been conducted for the acoustic mode and in‐shell acoustic response; the correctness of the finite element model is verified via comparison with theoretical and measured data. On this basis, the impacts of porous material fluid bulk properties on the noise attenuation effect of the Al/MF cylinder shell are further studied within the frequency range of 0 ∼ 1000 Hz. It is suggested that fluid bulk properties changes pose relatively high impacts on internal noise response of a cylindrical cavity. Within low‐frequency and high‐frequency ranges, the response value of sound pressure increases with flow resistivity, while the response value of sound pressure decreases with the increases of tortuosity, porosity, flow resistivity (only for the medium frequency range), and viscous characteristic length in the medium and high frequencies ranges.
A reliability‐based method for optimizing airport collection and distribution network
Authors: Bao Danwen , Di Zhiwei , Zhang Tianxuan 
Published: October 2018

SummaryIn this article, a reliability‐based method for optimizing the road network is presented. A bi‐level optimization model for the road network, of which the lower model is the optimal user equilibrium of the road impedance function and the upper model is the maximum reliability of the network, is constructed and solved by using the genetic algorithm. Moreover, a model for measuring the travel time reliability of the airport collection and distribution network is built based on the improved Bureau of Public Roads (BPR) function, and the reliability of this road network is quantified. Results of our case study show that the mean travel time reliability of all roads in the collection and distribution network of Nanjing Lukou Airport is 0.74, showing a good status on the whole level compared with other roads. The mean travel time reliability of the roads near the airport is higher by 25% or so, indicating that the reliability distribution is significantly uneven. It is proved that this method has higher accuracy and is applicable to calculate airport collection and distribution network reliability. After optimized by using the bi‐level model, the reliability of the road network is increased by about 11%, showing a good optimization effect. However, the optimization process of genetic algorithm is greatly affected by both crossover rate and mutation rate. A higher mutation rate or lower crossover rate will decrease the stability of optimization process. This method can be used as a theoretical reference for optimizing airport collection and distribution networks and improving the efficiency of airport's external transportation service.
Study on the public intention for environmental protection based on social network
Authors: Li Xiaofei , Li Da 
Published: October 2018

SummaryOn the basis of public good game model, this paper allows for the two information states: complete and incomplete information structures, as well as the two ways of behavioral decision: strategic substitutes and strategic complements. Moreover, it systematically analyzes the influences of different social networks on individual behavioral decision for environmental protection. It is found by this study that (1) there is a more stable and effective equilibrium state for individuals to make decision by the strategic complements against the strategic substitutes in complete information structure; (2) in incomplete information structure, the individual decision behavior and earnings depend on the degree and connectivity of network structure. The findings are of practical significance for analyzing the influence of inherent psychological factors and external environmental factors on individuals' decision‐making for environmental protection. Moreover, they can become the targeted proposals in carrying forward participatory environmental protection systems and the public participation in environmental protection
Research on the correlation of port logistics and regional economic growth base on gray relational analysis method
Authors: Ding Hong‐chao , Lian Min‐rong , Chen Xue‐ying , Liu Jia‐ming , Zhong Zu‐chang , Zhang Yu‐fan , Zhou Min‐yao 
Published: October 2018

SummaryCostal Port, as modern transport hub and logistics nodes linking airlines, railways, highways, and other transport means, plays an important role in driving regional economic growth, while the regional growth in Port inter‐lands offer substantial support and guarantee for the port logistics. The correlation between port logistics and regional economic growth, therefore, may serve the entry point of research on the sustainable development of both Shenzhen and its port, given the positive interplay of the port logistics with regional economy, will gain a better strategic position in the Belt‐and‐Road Initiative and the Guangdong‐Hong Kong‐Macao Greater Bay Area. Gray correlation analysis and decision tree algorithm are both employed in the light of the status quo of ShenzhenPort to closely examine relevancy between the port logistics and regional economic development. The relevancy among gross industrial output value, total investment in fixed assets and gross import and export value reads 0.69:0.682:0.643, respectively, in contrast to the least relevancy of the construction industry; the gross industrial output value as well import and export value, according to the decision tree algorithms, exert decisive influences on the port logistics.
Mathematical analysis of financial decentralization and economic efficiency in both state‐owned and private enterprises
Authors: He Mei‐Ling , Jiang Qijie , Hong Zheng 
Published: October 2018

SummaryThe relationship between financial decentralization and economic efficiency has been a hot topic in the recent years. Modern enterprises, especially smart manufacturing enterprises, compared to traditional enterprises, have quantities of distinctive attributes. Given this situation, it is worthy of studying what role the financial decentralization plays in improving economic efficiency of both state‐owned and private enterprises. In this paper, a mathematical model is built and utilized to explore the determinants of financial decentralization and the relationship of financial decentralization and economic efficiency. Specifically, the model is extended from the overlapping generations model (OLG), and the first order condition is taken into account to maximize corporate profits and personal utility and to deduce the channels through which financial decentralization affects economic efficiency. Results show that financial decentralization is related to the size of the population employed by the private economy and it contributes to enhancing economic efficiency by affecting the capital efficiency of private companies and the capital quota of private enterprises. This paper theoretically enriches the literature on the factors of economic efficiency and has significant implications in economic efficiency.
A team task complexity measure for emergency procedures in fully automatic metro
Authors: Niu Ke , Fang Weining , Guo Beiyuan 
Published: October 2018

SummaryA measure of team task complexity for emergency procedures in fully automatic metro is proposed using a Euclidean norm based on two factors: internal complexity of network nodes Nodecom − inside and external complexity of network nodes Nodecom − outside. The development of the operation complexity measure followed four steps. First, team task complexity network for emergency procedures was constructed. Second, the task complexity (TC) method used as complexity measure of individual was adopted to measure the internal complexity of network nodes. Then, the external complexity of network nodes was measured by structure entropy. Finally, the team task complexity values for emergency procedures were determined by the Euclidean norm of the two factors. To verify the validity of this team task complexity measure, a one‐factor experiment was designed to test the proposed model. Thirteen team subjects participated in the experiment and performed 5 typical emergency scenes. Both objective indexes (TeamTIME) and subjective indexes (TeamWORKLOAD and TeamSUBCOMPLEXITY) were used in the experiment. The data analysis showed that the TeamTIME, TeamWORKLOAD, and TeamSUBCOMPLEXITY could be predicted well from the team task complexity value. The proposed team task complexity measure can be used for evaluation of emergency procedures design in fully automatic metro.