bluuebunny/crossref_metadata_2025_split huggingface dataset:
Différences en matière de santé mentale selon le statut de minorité sexuelle
Authors: Martin-Storey Alexa , Temcheff Caroline , Laventure Myriam , Lévesque Geneviève 
Published: July 2019

Objectif Les individus provenant d’une minorité sexuelle rapportent plus de problèmes de santé mentale que les individus ayant une identité hétérosexuelle. Or, la majorité des recherches canadiennes sur ce sujet ont été réalisées il y a plusieurs années, bien avant les changements culturels et légaux concernant la population lesbienne, gay et bisexuelle. Ces changements culturels, sociaux et légaux ont sans aucun doute influencé le portrait clinique de cette population. Cette étude vise à identifier les différences en santé mentale chez les gens qui sont issus ou non de minorités sexuelles.
Méthode Un échantillon régionalement représentatif d’adultes en Estrie, Québec (n = 10 687) a participé à un sondage téléphonique. Pour ce faire, les participants devaient répondre à des questions concernant leur identité sexuelle et la présence de problèmes de santé mentale incluant la détresse psychologique, la dépression, et de problèmes de surconsommation d’alcool et de drogues.
Résultats Les résultats ont indiqué plusieurs différences significatives entre les individus appartenant à une minorité sexuelle et les individus hétérosexuels. Les différences sont surtout observées lorsque les individus bisexuels ou principalement hétérosexuels sont comparés aux individus hétérosexuels. La majorité de ces différences sont principalement expliquées par les variables de contrôle (l’âge, le niveau d’éducation, le revenu et le fait d’appartenir à une minorité visible).
Conclusions Ces résultats suggèrent l’importance d’atténuer les différences sociodémographiques pour améliorer la santé mentale chez les individus issus d’une minorité sexuelle. Les vulnérabilités spécifiques des individus ayant une identité bisexuelle et principalement hétérosexuelle devraient être davantage considérées.
Le soutien des pairs souffrant de psychose : l’expérience du programme « Passer l’espoir au suivant »
Authors: Wallot Hubert-Antoine 
Published: July 2019

Pour les personnes souffrant d’un trouble de santé mentale, le soutien de pairs aidants (au sens de personnes s’étant rétablies d’un tel trouble) est d’une grande valeur thérapeutique. Les Alcooliques anonymes (AA) ont été les premiers à le démontrer. Leur approche comporte plusieurs éléments bénéfiques, tel les « meetings », le programme en « 12 étapes », et un élément majeur, le parrainage d’un individu par un pair. Depuis sont apparues des organisations reposant sur des groupes de pairs, et aussi cette nouvelle profession de « pair aidant ». Dans le contexte d’un centre de traitement pour personnes souffrant de troubles psychotiques majeurs, pour lesquels l’espoir est un ingrédient déterminant du rétablissement, l’article présente ici un programme d’entraide s’appuyant principalement sur un parrainage d’un client par un pair et qui, depuis son introduction, commence cliniquement à porter ses fruits. Le programme a aussi une composante de « meetings » et une composante des « 12 étapes ».
Le « divertissement connecté » au sein du foyer : une enquête auprès des jeunes Québécois
Authors: Millerand Florence , Thoër Christine , Duque Nina , Lévy Joseph Josy 
Published: July 2019

Cadre de la recherche : Internet constitue un mode d’accès aux contenus de divertissement audiovisuels (films, séries, vidéos YouTube, etc.) de plus en plus populaire, notamment chez les jeunes.
Objectifs : Cet article présente les résultats d’une recherche sur les pratiques de visionnement en ligne de contenus audiovisuels chez les jeunes Québécois de 12 à 25 ans, afin de comprendre comment ces pratiques s’articulent à la vie familiale.
Méthodologie : La stratégie méthodologique est de type mixte combinant des données qualitatives (14 groupes de discussion rassemblant 82 participants, 29 entrevues individuelles) et quantitatives (enquête par questionnaire auprès de 1504 jeunes Québécois âgés de 12 à 25 ans).
Résultats : Les résultats de la recherche révèlent une très forte individualisation dans les pratiques et une autonomie accrue des jeunes à l’égard des contenus regardés et des temps de visionnement. Les pratiques offrent des occasions de partage et d’expression des liens familiaux, allant jusqu’à participer à la formation de pratiques familiales spécifiques autour de rituels de visionnement.
Conclusions : Si la famille constitue le premier lieu de socialisation des jeunes à la télévision, elle joue également un rôle dans la formation des pratiques de visionnement des contenus audiovisuels sur Internet. En retour, ces pratiques numériques semblent contribuer encore davantage à l’acquisition de l’autonomie chez les jeunes, y compris chez les plus jeunes.
Contribution : En apportant de nouvelles connaissances sur le divertissement connecté chez les jeunes et sa place dans la vie familiale, l’article rend visible la pertinence sociale et scientifique des recherches sur les usages sociaux des technologies chez les jeunes.
Comparative Evaluation of Antioxidant Potential in Thermally Processed, Underutilized Food Grains of the Himalayan Region
Authors: Dutta Anuradha , Shukla Pushpa , Tilara Soni , Prasad Nivedita , Khan Raushan , Suri Shweta , Bharadwaj S. B. 
Published: July 2019

Aims: To determine the bioactive components and total antioxidant capacity (TAC) in selected underutilized crops of the Himalayan region viz. Barnyard millet, Grain amaranth, Rice bean, Black soybean and Horsegram.
Study Design: Experimental design (Lab experiment).
Place and Duration of Study: Department of Foods and Nutrition, College of Home Science, G. B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, in the year 2016-18.
Methodology: We applied different processing techniques (covered pan cooking and pressure cooking) in the underutilized crops and analyzed the total phenol, total flavonoids and total antioxidant capacity (Ferric reducing antioxidant power (FRAP) assay and (2, 2-Diphenyl-1-picrylhydrazyl) (DPPH) by using standard methods.
Results: It was found that black soybean had highest phenolic content after both thermal treatments (3233.76 mg GAE/100 g for pan cooked and 1883.11 mg GAE/100 g for pressure cooked samples) and TAC by both FRAP (6423.76 mg TE/100 g for pan-cooked and 4415.58 mg TE/100 g for pressure cooked) and DPPH (536.41 and 453.98 mg TE/100g for pan and pressure cooked samples, respectively) method. Among raw samples, rice bean contained the highest flavonoid content and TAC by FRAP assay. In contrast, raw grain Amaranth showed the lowest phenolic content. Further, pressure cooking was found to be better for barnyard millet, while in pulses, pan cooking yielded the best results (in terms of increased value/lower losses).
Conclusion: It can be concluded that among pulses pan cooked black soybean was found to have a good store of bioactive compounds as compared to rice bean and horse gram. The pressure cooking method was found to be suitable for millet like a barnyard.
Cancer in Cross River State
Authors: Ebughe G. A. , Ugbem T. I. , Ushie D. E. , Effewongbe S. 
Published: July 2019

Aims: To determine the prevalence of cancer in the rest of Cross River State not covered by the population-based cancer registry which is limited to the capital city of Calabar.
Study Design: Descriptive retrospective study involving a trend analysis of cancers from the rest of Cross River State not covered by the Calabar cancer registry. Cancers incident in the Pathology and Haematology departments of the University of Calabar Teaching hospital are included in the study.
Place and Duration of Study: Pathology and Haematology departments of the University of Calabar Teaching hospital. Data was assessed between April to May 2019.
Methodology: An institution-based trend analysis of cancers originating from the rest of Cross River State, out of population-based cancer registry’s coverage was carried out. Such cases incident in the Pathology and Hematology Departments of the University of Calabar Teaching Hospital were included. Cancer data from 1st January 2004 to 31st December 2013 was accessed from the archives of both departments. Data extraction was carried out though filling of a check list and these were fed into IBM statistical package for social sciences SPSS version 21 for analysis.
Results: Nine hundred and fourty one (941), cancer cases were diagnosed during this period. The mean age of diagnosis was 49.18 ± 18.9.Four hundred and seventy seven (477 or 50.69%) females and 464 or 49.31% males had cancer, representing a female to male ratio 0.97: 1. Overall, the commonest age group was 40 to 64 years (46.3%), followed by 18 to 39 years (25.5%), and 65 years or greater (23.0%).Breast cancer followed by prostate cancer were the commonest cancers in adults, while cancers in the lymphohaematopoietic tissue, soft tissue and eye were the commonest in children.
Conclusion: Cancer occurs at an earlier age in the rest of Cross River State, with breast and prostatic cancer dominating. Efforts should be doubled to institute effective screening programmes.
Technical note: A modified gamma evaluation method for dose distribution comparisons
Authors: Yu Liting , Kairn Tanya , Trapp Jamie , Crowe Scott B. 
Published: July 2019

AbstractPurposeIn this work we have developed a novel method of dose distribution comparison, the inverse gamma (IG) evaluation, by modifying the commonly used gamma evaluation method.MethodsThe IG evaluation calculates the gamma criteria (dose difference criterion, ΔD, or distance‐to‐agreement criterion, Δd) that are needed to achieve a predefined pass rate or gamma agreement index (GAI). In‐house code for evaluating IG with a fixed ΔD of 3% was developed using Python (v3.5.2) and investigated using treatment plans and measurement data from 25 retrospective patient specific quality assurance tests (53 individual arcs).ResultsIt was found that when the desired GAI was set to 95%, approximately three quarters of the arcs tested were able to achieve Δd within 1 mm (mean Δd: 0.7 ± 0.5 mm). The mean Δd required in order for all points to pass the gamma evaluation (i.e., GAI = 100%) was 4.5 ± 3.1 mm. The possibility of evaluating IG by fixing the Δd or ΔD/Δd, instead of fixing the ΔD at 3%, was also investigated.ConclusionThe IG method and its indices have the potential to be implemented clinically to quantify the minimum dose and distance criteria based on a specified GAI. This method provides additional information to augment standard gamma evaluation results during patient specific quality assurance testing of individual treatment plans. The IG method also has the potential to be used in retrospective audits to determine an appropriate set of local gamma criteria and action levels based on a cohort of patient specific quality assurance plans.
Development and clinical implementation of eclipse scripting‐based automated patient‐specific collision avoidance software
Authors: Mann Thomas D. , Ploquin Nicolas P. , Gill William R. , Thind Kundan S. 
Published: July 2019

AbstractPurposeIncreased use of Linac‐based stereotactic radiosurgery (SRS), which requires highly noncoplanar gantry trajectories, necessitates the development of efficient and accurate methods of collision detection during the treatment planning process. This work outlines the development and clinical implementation of a patient‐specific computed tomography (CT) contour‐based solution that utilizes Eclipse Scripting to ensure maximum integration with clinical workflow.MethodsThe collision detection application uses triangle mesh structures of the gantry and couch, in addition to the body contour of the patient taken during CT simulation, to virtually simulate patient treatments. Collision detection is performed using Binary Tree Hierarchy detection methods. Algorithm accuracy was first validated for simple cuboidal geometry using a calibration phantom and then extended to an anthropomorphic phantom simulation by comparing the measured minimum distance between structures to the predicted minimum distance for all allowable orientations. The collision space was tested at couch angles every 15° from 90 to 270 with the gantry incremented by 5° through the maximum trajectory. Receiver operating characteristic curve analysis was used to assess algorithm sensitivity and accuracy for predicting collision events. Following extensive validation, the application was implemented clinically for all SRS patients.ResultsThe application was able to predict minimum distances between structures to within 3 cm. A safety margin of 1.5 cm was sufficient to achieve 100% sensitivity for all test cases. Accuracy obtained was 94.2% with the 5 cm clinical safety margin with 100% true positive collision detection. A total of 88 noncoplanar SRS patients have been currently tested using the application with one collision detected and no undetected collisions occurring. The average time for collision testing per patient was 2 min 58 s.ConclusionsA collision detection application utilizing patient CT contours was developed and successfully clinically implemented. This application allows collisions to be detected early during the planning process, avoiding patient delays and unnecessary resource utilization if detected during delivery.
Lupus Low Disease Activity State and Reduced Direct Health Care Costs in Patients With Systemic Lupus Erythematosus
Authors: Yeo Ai Li , Koelmeyer Rachel , Kandane‐Rathnayake Rangi , Golder Vera , Hoi Alberta , Huq Molla , Hammond Edward , Nab Henk , Nikpour Mandana , Morand Eric F. 
Published: July 2019

ObjectiveTreat‐to‐target end points for systemic lupus erythematosus (SLE) have been assessed for their impact on damage accrual and flare, but whether they have an impact on the high health care utilization and costs in SLE has not been studied. The purpose of this study was to examine our hypothesis that the recently described lupus low disease activity state (LLDAS) would be associated with reduced health care cost.MethodsData from a single tertiary hospital longitudinal SLE cohort were assessed. Baseline demographics, disease activity (Systemic Lupus Erythematosus Disease Activity Index 2000 [SLEDAI‐2K], physician global assessment [PhGA], and flare index), and medication use were evaluated, and direct health care utilization and cost data were obtained from hospital information systems. LLDAS was defined as previously published: briefly, SLEDAI‐2K ≤4 with no new activity, PhGA ≤1, prednisolone ≤7.5 mg/day, and optimal standard immunosuppressive agents. Analysis was performed using multivariable linear regression.ResultsTwo hundred SLE patients, contributing 357.8 person‐years of observation, were included. A history of lupus nephritis was present in 42% of patients, and damage (Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index >0) was present at study commencement in 57.3% of patients. The mean ± SD annual direct medical cost per patient was US$7,413 ± 13,133/year. In multivariable analysis, increased cost was associated with the presence of baseline organ damage (41.7% increase; P = 0.009) and corticosteroid use (>7.5–15 mg/day: 55.7% increase; P = 0.02; and >15 mg/day: 202% increase; P < 0.001). In contrast, spending ≥50% of the observation period in LLDAS was associated with a 25.9% reduction in annual direct medical cost (P = 0.04).ConclusionGreater time spent in LLDAS was associated with significantly reduced direct hospital health care costs among patients with SLE.
Development of Resilience Among Rheumatoid Arthritis Patients: A Qualitative Study
Authors: Shaw Yomei , Bradley Matthew , Zhang Chen , Dominique Alyssa , Michaud Kaleb , McDonald David , Simon Teresa A. 
Published: July 2019

ObjectiveResilience, the ability to recover from and adapt successfully to stressful situations, is a valuable resource for patients who live with chronic conditions. This qualitative study examines the development of resilience among rheumatoid arthritis (RA) patients. We aimed to describe the resilience development process and to describe strategies used by patients to cultivate resilience.MethodsOur approach combined ethnographic data collection and narrative analysis methods. Semistructured interviews were conducted with adult RA patients in the US. Interviewees were asked to discuss their experiences with diagnosis, living with RA, coping with challenges, treatment, and health care providers. The interviews were audiorecorded, transcribed, and analyzed to describe the stages of resilience development and to identify patients’ strategies for building/maintaining resilience.ResultsEighteen patients were interviewed, ages 27–80 years and with RA duration of 5–41 years. Patient responses to challenging situations were grouped into 3 stages: 1) lacking capacity to handle the situation, 2) struggling but growing in capacity to handle the situation, and 3) attaining mastery. Patients used 10 strategies to cultivate resilience: perseverance, exchanging social support, pursuing valued activities, flexibility, positive reframing, acceptance, humor, avoiding threatening thoughts, equanimity, and maintaining a sense of control.ConclusionRA patients acquire resilience in a dynamic process of learning in response to new challenges. Patients use a combination of behavioral and emotion management strategies to cultivate resilience. Awareness of these strategies may benefit patients, health care providers, and researchers developing behavioral interventions and social support programs in the context of RA and other chronic diseases.
In Vivo Imaging of Composite Hydrogel Scaffold Degradation Using CEST MRI and Two‐Color NIR Imaging
Authors: Zhu Wei , Chu Chengyan , Kuddannaya Shreyas , Yuan Yue , Walczak Piotr , Singh Anirudha , Song Xiaolei , Bulte Jeff W. M. 
Published: July 2019

AbstractHydrogel scaffolding of stem cells is a promising strategy to overcome initial cell loss and manipulate cell function post‐transplantation. Matrix degradation is a requirement for downstream cell differentiation and functional tissue integration, which determines therapeutic outcome. Therefore, monitoring of hydrogel degradation is essential for scaffolded cell replacement therapies. It is shown here that chemical exchange saturation transfer magnetic resonance imaging (CEST MRI) can be used as a label‐free imaging platform for monitoring the degradation of crosslinked hydrogels containing gelatin (Gel) and hyaluronic acid (HA), of which the stiffness can be fine‐tuned by varying the ratio of the Gel:HA. By labeling Gel and HA with two different near‐infrared (NIR) dyes having distinct emission frequencies, it is shown here that the HA signal remains stable for 42 days, while the Gel signal gradually decreases to <25% of its initial value at this time point. Both imaging modalities are in excellent agreement for both the time course and relative value of CEST MRI and NIR signals (R2= 0.94). These findings support the further use of CEST MRI for monitoring biodegradation and optimizing of gelatin‐containing hydrogels in a label‐free manner.
Significant Role of Al in Ternary Layered Double Hydroxides for Enhancing Electrochemical Performance of Flexible Asymmetric Supercapacitor
Authors: Gao Xiaorui , Liu Ximeng , Wu Dajun , Qian Bin , Kou Zongkui , Pan Zhenghui , Pang Yajun , Miao Linqing , Wang John 
Published: July 2019

AbstractThe Al effect on the electrochemical properties of layered double hydroxides (LDHs) is not properly probed, although it is demonstrated to notably promote the capacitive behavior of LDHs. Herein, ternary NiCo2Alx layered double hydroxides with varying levels of Al stoichiometry are purposely developed, grown directly on mechanically flexible and electrically conducting carbon cloth (CC@NiCo2Alx‐LDH). Al plays a significant role in determining the structure, morphology, and electrochemical behavior of NiCo2Alx‐LDHs. At an increasing level of Al in NiCo2Alx‐LDHs, there is a steady evolution from 1D nanowire to 2D nanosheets. The CC@NiCo2Al‐LDH at an appropriate level of Al and with the nanowire–nanosheet mixed morphology exhibits both significantly enhanced electrochemical performance and excellent structural stability, with about a 2.3‐fold capacitance of NiCo2‐OH. When applied as the anode in a flexible asymmetric supercapacitor (ASC), the CC@NiCo2Al‐LDH gives rise to a remarkable energy density of 44 Wh kg−1 at the power density of 462 W kg−1, together with remarkable cyclic stability with 91.2% capacitance retention over 15 000 charge–discharge cycles. The present study demonstrates a new pathway to significantly improve the electrochemical performance and stability of transition metal LDHs, which are otherwise unstable in structure and poorly performing in both rate and cycling capability.
A Long Lifetime Aqueous Organic Solar Flow Battery
Authors: Li Wenjie , Kerr Emily , Goulet Marc‐Antoni , Fu Hui‐Chun , Zhao Yuzhou , Yang Ying , Veyssal Atilla , He Jr‐Hau , Gordon Roy G. , Aziz Michael J. , Jin Song 
Published: July 2019

AbstractMonolithically integrated solar flow batteries (SFBs) hold promise as compact stand‐alone energy systems for off‐grid solar electrification. Although considerable research is devoted to studying and improving the round‐trip efficiency of SFBs, little attention is paid to the device lifetime. Herein, a neutral pH aqueous electrolyte SFB with robust organic redox couples and inexpensive silicon‐based photoelectrodes is demonstrated. Enabled by the excellent stability of both electrolytes and protected photoelectrodes, this SFB device exhibits not only unprecedented stable continuous cycling performance over 200 h but also a capacity utilization rate higher than 80%. Moreover, through comprehensive study on the working mechanisms of SFBs, a new theory based on instantaneous solar‐to‐output electricity efficiency toward more optimized device design is developed and a significantly improved solar‐to‐output electricity efficiency of 5.4% from single‐junction silicon photoelectrodes is realized. The design principles presented in this work for extending device lifetime and boosting round trip energy efficiency will make SFBs more competitive for off‐grid applications.
Rational Core–Shell Design of Open Air Low Temperature In Situ Processable CsPbI3 Quasi‐Nanocrystals for Stabilized p‐i‐n Solar Cells
Authors: Xi Jun , Piao Chengcheng , Byeon Junseop , Yoon Jungjin , Wu Zhaoxin , Choi Mansoo 
Published: July 2019

AbstractAs a promising alternative, inorganic perovskite nanocrystals allow reinforced stability of photovoltaic device. Unfortunately, directly assembling these nanocrystals into film is uncontrollable. Instead, in situ assembling technology under low temperature in open air is attractive but limited due to the tendency of nonperovskite transition. The adverse shell ligands and unstable core lattices are known as the fundamental problems. In order to address this issue, here proposed is a rational core–shell design: 1) with respect to ligands, a new one, 4‐fluorophenethylammonium iodide, is used to enhance bonding force and charge coupling between ligands and nanocrystals; 2) with respect to lattices, a novel compound H2PbI4 is employed to assist divalent ion (Mn2+) doping into perovskite lattices. By low temperature in situ processing CsPbI3 quasi‐nanocrystal film, the highest power conversion efficiency of 13.4% for p‐i‐n solar cells is achieved, which retains 92% after 500 h in ambient air. The current study underlines the significance of rational hierarchical design of inorganic perovskite nanocrystals, especially for low temperature in situ processable electronic devices.