bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability of Semitendinosus and Biceps Femoris Aponeurosis Thickness Using B‐Mode Ultrasound
Authors: Sahinis Chrysostomos , Kellis Eleftherios 
Published: November 2024

ObjectivesThe aim of the present study was to assess the reliability of aponeurosis and muscle thickness of the hamstrings using ultrasound (US).MethodsUS images were captured from the semitendinosus (ST) and biceps femoris long head (BFlh) of 30 individuals (15 females), undergoing two testing sessions with a 24‐hour interval. Measurements were taken at six sites along the thigh at two knee angles (0° = full extension and 90°) in prone position. Aponeurosis and muscle thickness across the entire length of ST and BFlh were evaluated using computational image segmentation which generated ~360 data points per participant.ResultsThe intraclass correlation coefficients ranged from 0.937 to 0.998 while the standard error of measurement varied from 0.88 to 2.72% for superficial aponeurosis, from 1.41 to 2.29% for deep aponeurosis, and from 1.50 to 4.22% for muscle thickness. The minimal detectable change ranged from 2.44 to 7.56% for the superficial aponeurosis, from 3.57 to 6.27% for deep aponeurosis, and from 4.17 to 11.70% for BF and ST muscle thickness.ConclusionsEvaluation of hamstring aponeurosis and muscle thickness measurements at rest displayed very high reliability and, hence, such measurements can be used to diagnose changes in thickness due to injury or exercise interventions.
The Impact of Slight to Mild Hearing Loss on Academic Performance and Behavior of 9–15‐Year‐Olds
Authors: Reijers Stefanie N.H. , Vroegop Jantien L. , Jansen Pauline W. , Kremer Bernd , van der Schroeff Marc P. 
Published: November 2024

ObjectiveTo examine the impact of slight to mild hearing loss in children by studying its association with academic performance and behavioral problems.MethodsThis study was embedded within a prospective birth cohort in Rotterdam, the Netherlands. Participants underwent audiometric and behavioral evaluations between ages 9–11 (April 2012–October 2015) and 13–15 (May 2017–September 2019). At 13–15, a multiple linear regression was conducted to explore the relationship between hearing acuity and both academic and behavioral outcomes. A cross‐lagged analysis using data from ages 9 to 11 investigated bidirectional associations between hearing loss and behavioral problems.ResultsThe cross‐sectional part of the study involved 4688 participants at the age of 13–15 years. The relative risk for children with slight to mild hearing loss of being placed in a lower educational level compared with the highest level was 1.52 (95% confidence interval (CI) [1.14, 2.02]). Among boys, elevated high‐frequency pure‐tone average (HPTA) was associated with a higher total problem score (per 1 dB HPTA: β = 0.01; 95% CI [0.00, 0.02]). For girls, elevated low‐frequency pure‐tone average (LPTA) was associated with a higher attention problem score (per 1 dB LPTA: β = 0.02; 95% CI [0.01, 0.02]). Cross‐lagged effects showed that participants with increased pure‐tone averages in low frequencies at 9–11 years had more social problems at ages 13–15 years (Z‐score difference: 0.01; 95% CI [0.01, 0.02]).ConclusionElevated hearing thresholds in slight to mild hearing loss were linked to poorer academic performance and increased behavioral problems.Level of Evidence2 (prospective cohort study) Laryngoscope, 2024
Temporal Trends in Soil Health and Productivity on Reclaimed Natural Gas Pipeline Rights‐of‐Way on Cropland
Authors: Muitire Clemence , Zvomuya Francis , Adesanya Theresa , Amarakoon Inoka , Mante Afua 
Published: November 2024

ABSTRACTThe construction of underground pipelines negatively impacts soil productivity in various ecosystems. However, the temporal progression in the recovery of soil productivity following the reclamation of cropland impacted by natural gas pipeline rights‐of‐way (ROWs) construction remains unclear. This study examined temporal, post‐reclamation changes in selected soil health indicators and productivity on reclaimed underground natural gas pipeline ROWs on cropland. Soil and crop samples were collected from ROWs ranging in time elapsed since reclamation (TSR) from 6 to 12 years and from adjacent undisturbed locations (off‐ROW) in the same field. The soil samples were analyzed for soil health indicators (permanganate‐oxidizable carbon (POXC), soil respiration, and autoclaved citrate‐extractable (ACE) protein) and selected chemical properties. Crop samples were assessed for grain and total biomass yields as well as grain protein content. Compared to the off‐ROW, soil organic C on the ROWs was 29% (6‐year ROW) and 33% (9‐year ROW) lower than on the off‐ROWs. Soil respiration recovered within 6 years of ROW reclamation, whereas it took 12 years for POXC and ACE protein to recover to off‐ROW levels. Grain and biomass yields 12 years post‐reclamation were still 42% and 36%, respectively, lower on the ROWs than on the off‐ROWs. However, measured soil attributes recovered faster than crop variables, indicating that pipeline construction on cropland has longer‐term impacts on crop yields than on soil attributes. These results indicate that, although underground pipeline construction has detrimental impacts on soil and crop attributes, these attributes would slowly recover to pre‐construction levels with increasing TSR.
Common sports‐related nerve injuries seen by the electrodiagnostic medical consultant
Authors: Farag Jordan I. , McDougall Alexandre N. , Catapano Michael 
Published: November 2024

AbstractThe high physiologic demands of sports create dynamic stress on joints, soft tissues, and nerves which may lead to injuries in the athlete. Electrodiagnostic (EDx) assessment is essential to identify the correct diagnosis, localization, and prognosis, to guide management of sports‐related neuropathies. A comprehensive review was performed to provide the EDx medical consultant with a practical approach to the common peripheral nerve disorders seen in athletes. Sports‐related neuropathies reviewed include transient traumatic irritation of the brachial plexus and/or cervical nerve roots (“Burners and stingers,”) suprascapular and axillary neuropathies, ulnar neuropathy at the elbow (UNE) in throwers, ulnar neuropathy at the hand/wrist in cyclists, multi‐ligamentous knee injury, and foot/ankle neuropathies including tarsal tunnel syndrome. A thorough understanding of peripheral anatomy, possible entrapment sites, mechanisms of injury, and key physical examination findings is essential for correct diagnosis. EDx assessments beyond routine studies are generally required for sports‐related neuropathy, which may not necessarily follow typical entrapment patterns. Adjunct diagnostic imaging, such as point‐of‐care ultrasound and magnetic resonance imaging, are helpful tools to identify associated musculoskeletal pathology such as compressive cysts or nerve entrapment, which may be amenable to interventional or surgical treatment. When no clear reversible structural pathology exists, management of sports‐related neuropathy is athlete‐specific and generally multi‐modal, involving a combination of physical rehabilitation techniques to address muscle imbalances, load management, protective equipment, and interventional pain procedures.
On the role of local reinforcement in an adhesively bonded AL/CFRP energy absorber under axial loading: A theoretical investigation and optimization
Authors: Rahmani Reza , Keshavarzi Ali , Googarchin Hamed Saeidi 
Published: November 2024

AbstractThis paper aims to develop a novel theoretical model that incorporates the effects of local composite reinforcement using adhesive bonding on the energy absorption of aluminum structures under axial loading. The goal is to optimize energy absorption prior to any connection failures and to prevent uneven structural deformation. Moreover, it strives to reduce the structure's weight and material usage, achieving superior results compared to traditional global reinforcement techniques. The theoretical model was validated through experimental testing and finite element analysis, demonstrating good agreement with the predicted results. The results reveal that increasing the CFRP fiber angle, layer thickness, and number of layers generally leads to improved energy absorption capacity. An optimization analysis was performed to determine the optimal design parameters, yielding a fiber angle of 80°–90°, composite thickness of 1.5 mm, and aluminum thickness of 2.5 is the best configuration, offering the highest specific energy absorption and adequate peak load capacity for maximized energy absorption. The proposed model offers significant improvements over existing approaches, enhancing the predictive capabilities and practical applicability of energy absorption predictions in engineering design.Highlights
A novel theoretical model for energy absorption in locally reinforced hybrid AL/CFRP structures.
The influence of design parameters, such as CFRP layer count, fiber orientation, and thickness ratio.
Optimization to maximize the average crushing force while meeting weight and geometric constraints.
Findings can inform the design of safer and more efficient energy‐absorbing structures in various applications.
Pine Needle of Pinus koraiensis (Siebold & Zucc) Essential Oil Through Liquid Nitrogen Quick‐Freezing Assisted Solvent‐Free Microwave Extraction Process for Antibacterial Application
Authors: Yu Shuai , Ma Shengtao , Wang Qiuling , Chen Zhifei , Xi Gaolei , An Nan , Yao Hanning , Jia Tao , Zhao Xiuhua , Yang Lei 
Published: November 2024

ABSTRACTIntroductionThis study investigates the composition and antibacterial properties of essential oil extracted from Pinus koraiensis (Siebold & Zucc) pine needles using a liquid nitrogen freezing treatment combined with solvent‐free microwave extraction (LNSFM).ObjectiveThe aim is to develop a low‐energy, high‐efficiency extraction method for conifer essential oils, analyze their chemical composition, and evaluate their antibacterial efficacy.MethodologyPine needle samples were frozen with liquid nitrogen and subsequently crushed. The essential oil was extracted using solvent‐free microwave technology. A single‐factor test and response surface methodology were employed to optimize extraction parameters. The extraction efficiency of LNSFM was compared with traditional methods through kinetics, and the essential oil components were analyzed using gas chromatography–mass spectrometry (GC–MS). The antibacterial activity of the extracted volatile oil was tested against Escherichia coli and Staphylococcus aureus.ConclusionLNSFM proves to be a green and efficient extraction method suitable for obtaining volatile oils from pine needles, which demonstrate significant antibacterial properties.
Screening Anti–Rheumatoid Arthritis Synovitis Effective Ingredients of Total Flavonoid From Artemisia argyi Folium Based on Spectrum–Effect Relationship
Authors: Shi Yu , Lei Yueyue , Guo Shiwen , Li Lujun , Li Xu , Liu Xinyi , Ding Shuiping 
Published: November 2024

ABSTRACTIntroductionFlavonoids are the main nonvolatile component responsible for the anti–rheumatoid arthritis (RA) synovitis activities of Artemisia argyi Folium. However, the effective ingredient remains unidentified. Spectrum–effect relationships analysis was a reliable and efficient strategy for herbal effective ingredient discovery.ObjectivesThis study aimed to screen the effective ingredients within the total flavonoid from Artemisia argyi Folium (TFAA) that exhibit anti‐RA synovitis activities based on spectrum–effect relationship.MethodsTFAA was obtained through ethanol extraction and subsequent purification with D101 resin from 15 distinct batches of Artemisia argyi Folium. The fingerprint of TFAA was established using HPLC, and its efficacy against RA synovitis was evaluated by determining the inhibition rate of nitric oxide (NO) on MH7A synovioblast induced by TNF‐α. Common peaks were identified using HPLC‐MS/MS and authentic standards. The spectrum–effect relationships between the fingerprints and efficacy were analyzed by gray relational analysis (GRA), canonical correlation analysis (CCA), and partial least squares regression analysis (PLSR) to pinpoint the peaks responsible for the anti‐RA synovitis activity, and the results were further verified by in vitro anti‐RA synovitis experiments and molecular docking studies.ResultsThe fingerprint revealed 14 common peaks, and 12 compounds were identified, including four caffeoylquinic acids and eight flavonoids. Among them, five flavonoids—X10 (hispidulin), X11 (jaceosidin), X12 (centaureidin), X13 (eupatilin), and X14 (casticin)—were highly relevant to anti‐RA synovitis activity. Verification experiments confirmed their inhibitory effect on NO production and cytokine secretion in MH7A cells, showing anti‐RA synovitis potential, which was consistent with the established spectrum effect relationship. The underlying mechanism might be related to the inhibition of iNOS.ConclusionHispidulin, jaceosidin, centaureidin, eupatilin, and casticin were the key effective ingredient of TFAA responsible for its anti‐RA synovitis effects. These compounds can serve as quality control markers for Artemisia argyi Folium and as lead compounds for anti‐RA synovitis treatment.
Double Copy From Tensor Products of Metric BV■‐Algebras
Authors: Borsten Leron , Jurčo Branislav , Kim Hyungrok , Macrelli Tommaso , Saemann Christian , Wolf Martin 
Published: November 2024

AbstractField theories with kinematic Lie algebras, such as field theories featuring color–kinematics duality, possess an underlying algebraic structure known as BV■‐algebra. If, additionally, matter fields are present, this structure is supplemented by a module for the BV■‐algebra. The authors explain this perspective, expanding on our previous work and providing many additional mathematical details. The authors also show how the tensor product of two metric BV■‐algebras yields the action of a new syngamy field theory, a construction which comprises the familiar double copy construction. As examples, the authors discuss various scalar field theories, Chern–Simons theory, self‐dual Yang–Mills theory, and the pure spinor formulations of both M2‐brane models and supersymmetric Yang–Mills theory. The latter leads to a new cubic pure spinor action for 10‐dimensional supergravity. A homotopy‐algebraic perspective on colour–flavour‐stripping is also given, obtain a new restricted tensor product over a wide class of bialgebras, and it is also show that any field theory (even one without colour–kinematics duality) comes with a kinematic ‐algebra.
Contextualising sustainable transhumant pastoralism: A systematic review
Authors: Azerigyik Richard Apatewen , Owusu‐Ansah Justice , Poku‐Boansi Michael , Agyei Frank Kwaku 
Published: November 2024

AbstractTranshumant pastoralism and sustainable development are two concepts that have long been treated as mutually exclusive elements in research on agriculture and livestock production. This study, therefore, aimed to establish the critical link between the two concepts by exploring the effects of transhumant pastoralism on economic, environmental and social sustainability, thereby conceptualising it within the broader sustainable development discourse. The study adopted a systematic literature review methodology to synthesise 145 studies related to the role of transhumant pastoralism in sustainable development in sub‐Saharan Africa. The paper employed thematic analysis to investigate the nature of transhumance and its implications for sustainability. The thematic analysis was based on the tripartite dimensions of sustainability—social, economic and environmental. The findings indicate that transhumance substantially impacts economic sustainability through the preservation of livelihoods, the creation of employment opportunities, and the generation of revenue. Nonetheless, it also poses challenges such as crop damage and the spread of zoonotic diseases, adversely affecting economic stability. Socially, transhumance promotes ethnoreligious cooperation and integration, enhancing social cohesion, but it also contributes to conflicts and security concerns. From the environmental perspective, transhumance has the potential to mitigate overgrazing and facilitate ecosystem regeneration. However, it is also linked to water contamination, deforestation, and the proliferation of invasive species. The study concluded that sustainable transhumant pastoralism must be conceptualised holistically, addressing the dimensions of sustainability simultaneously. It is recommended that effective stakeholder collaboration and comprehensive policy interventions be used to harness the benefits of transhumance while minimising its adverse effects.
Exploring the role of sustainability reporting strategies in promoting sustainable development in social economy entities: The circular economy as a mediator
Authors: Gallardo‐Vázquez Dolores , de Sousa Paiva Inna Choban , Nuevo‐Gallardo Cristina 
Published: November 2024

AbstractThis study focused on the relationship between sustainability reporting (SR), the circular economy (CE), and the United Nations' Sustainable Development Goals (SDGs), including an examination of the mediator role of the CE in the SR–SDGs relationship. The SR concept refers to the ways in which companies communicate with their internal and external stakeholders about their sustainability initiatives. Researchers have confirmed that the CE contributes to the achievement of SDGs based on SR. However, the literature does not offer any comprehensive frameworks that integrate these three concepts, which constitutes an important research gap. More specifically, very few studies have explored how social economy entities (SEEs) report the ways they contribute to achieving the SDGs while implementing CE practices. This research thus sought to make a significant contribution to filling this lacuna. Statistical analyses were conducted to determine how SR influences SDGs and how SR promotes these goals through the CE. Variance‐based structural equation modeling via partial least squares was applied to process data on a sample of 90 SEEs in Spain. The results show that entities that provide sufficient SR often communicate how they are implementing SDGs. CE practices have a significant effect on this SR–SDGs relationship. The findings thus make an important contribution to the literature by exploring the link between these three strategies (i.e., SR, the SDGs, and the CE) in organizational contexts and thus providing a foundation for new business models.
Structure Activity Relationship of Diarylidenecyclopentanone Derivatives as Potent Antiplasmodial Agents
Authors: Tamang Nitesh , Yadav Mamta , Joshi Mayank , Choudhury Angshuman Roy , Golakoti Nageswara Rao , Sahal Dinkar 
Published: November 2024

AbstractIn our efforts to design mono‐carbonyl analogues of curcumin with potential antiplasmodial activity, diarylidenecyclopentanone (DACP) derivatives, Ia–Iu and II–V, have been synthesized and characterized using 1H NMR, 13C NMR, IR, UV–Vis, and mass spectrometry. Structure of one of these DACPs has been verified by single crystal XRD. At the outset, all 25 DACPs were first screened at 12.5 µM for their in vitro antiplasmodial activity against the chloroquine (CQ)‐sensitive Pf3D7. The three most potent compounds (In, It, and Ik) were further tested at <10 µM concentrations against Pf3D7, PfINDO (CQ resistant), and PfMRA‐1240 (Artemisinin resistant) strains for determination of their IC50s and resistance indices. The drug profile of the DACPs was found to be very promising, with the most active compound It (IC50 1.39 µM against PfINDO) showing a selectivity index of ∼17 tested using HUH‐7 and HEK‐293T mammalian cell lines. Molecular docking studies with Pf pyridoxal synthase showed a good correlation between docking scores of DACPs and in vitro antiplasmodial activity. Further, high conformity with Lipinski's parameters indicates that these DACPs are promising antiplasmodial lead compounds.
Synthesis, Theoretical Gaussian Quantum Chemical Calculations, and Spectroscopic Elucidation of N‐(4‐bromophenyl)‐10H‐phenothiazine‐10‐carboxamide
Authors: Dugar Neeru , Jupudi Srikanth 
Published: November 2024

AbstractPhenothiazine derivative N‐(4‐bromophenyl)‐10H‐phenothiazine‐10‐carboxamide (BPC), a novel compound is selected for the present study based on the reported effectiveness of phenothiazine towards neurodegenerative diseases. Synthesis and characterization of BPC are carried out in the present work. To comprehend the electronic and structural aspects of BPC, quantum chemical studies are performed. Computational aspects using the density functional theory method using B3LYP/6–31 G ++(d,p) as a basis set are studied for the geometry optimization of the molecule. To analyze the reactivity, stability, and intramolecular interactions of the compound frontier orbital molecular analysis, molecular electrostatic potential distribution, and Fukui function are implemented. Calculations have been made to determine the electrophilic and nucleophilic descriptors of the title compounds by Fukui function evaluations on atomic charges. To visualize and quantify the localization of electrons and molecular orbitals in the molecule, electron localization function, localized orbital locator analysis and orbital localization analysis are carried out for a better understanding of chemical bonding. Basin Analysis is used for analysis of the nature of chemical bonds and interactions. To understand bond strengths, hyperconjugation, and reactivity natural bond orbital analysis is performed.
Biowaste‐Mediated Synthesis of CeO₂–TiO₂ Nanoparticles: An Efficient Recoverable Nanocatalyst for the Solvent‐Free Synthesis of Antipyrine Derivatives and Their Biological Evaluation
Authors: Dwivedi Bhaskar , Bhardwaj Diksha , Choudhary Deepika 
Published: November 2024

AbstractA facile, efficient, and environmentally friendly protocol for the solvent‐free synthesis of antipyrine‐ linked quinoline derivatives catalyzed by CeO2–TiO2 nanocatalyst under ultrasonication is developed. Antipyrine derivatives are involved in various synthetic processes and exhibit valuable biological activities, such as antibacterial, anti‐inflammatory, antioxidant, and anticancer properties. Biowaste‐ derived CeO2–TiO2 nanoparticles have been synthesized using outer covering calyx leaves extract of Physalis peruviana fruits and utilized for the construction of biologically important antipyrine derivatives by the multicomponent reaction in short reaction time with excellent yield. The nanocatalyst was characterized by FT‐IR, powder X‐ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and electron dispersion spectroscopy (EDS). The functionalized nanoparticles show excellent reusability without any significant loss in catalytic activity. The hot filtering experiment shows that there is no noticeable leaching or boomerang effect and that the catalysis is heterogeneous in nature. All synthesized compounds underwent screening for antibacterial activity against selected microorganisms, and their antioxidant activity was assessed using DPPH (2,2‐diphenyl‐1‐picrylhydrazyl). Some of the synthesized compounds exhibited promising results in both screenings.