bluuebunny/crossref_metadata_2025_split huggingface dataset:
Professional and personal conduct – what's expected?
Authors: Collier Andrew 
Published: September 2019

Dental nurse registration with the General Dental Council gives rights and privileges but also responsibilities and obligations. Andrew Collier shines a light on what this means for the dental nurse Aim To describe the ethical and legal obligations of a registered dental nurse and inform where to seek guidance regarding those obligations Objectives To have an enhanced understanding of a dental nurse's professional role and responsibilities when treating patients To have an enhanced understanding of a dental nurse's professional responsibilities outside of the workplace To understand the dental nurse's Continuing Professional Development (CPD) obligations and where to seek further guidance To understand the dental nurse's indemnity/insurance obligations and where to seek further guidance GDC development outcomes A and D
EVALUASI PROPERTI PSIKOMETRIS DAN PERBANDINGAN MODEL PENGUKURAN KONSTRUK SUBJECTIVE WELL-BEING
Authors: Akhtar Hanif 
Published: September 2019

In the subjective well-being (SWB) measurement model, there are three models used by researchers, namely one-factor model (unidimension), two-factors model, and three-factor model. This study aims to test the validity and reliability of the SWB measure and compare the measurement model of SWB with confirmatory factor analysis method. The total subjects used in this study were 1,003 people with an age range of 14 - 50 years. Positive Affect Negative Affect Schedule (PANAS) and Satisfaction with Life Scale (SWLS) were used as SWB measurements. The results showed all dimensions have Alpha reliability above 0.80 with item-total correlation above 0.3. The results of exploratory factor analysis showed that all items are well distributed to their dimensions with a factor loading above 0.4. Thus the scale in this study has satisfactory validity and reliability. The comparison of three hypothetical model showed that the three-factor model has the best model fit compared to the other two models. This finding provides evidence that the three components in the SWB construct are separate and independent of each other.
PERAN KESEIMBANGAN PEKERJAAN-KELUARGA DAN KUALITAS HIDUP TERHADAP KEBAHAGIAAN KERJA PADA PETUGAS PEMASYARAKATAN PEREMPUAN
Authors: Ratnaningsih Ika Zenita , Prasetyo Anggun Resdasari 
Published: September 2019

Correctional officers encounter vulnerable working conditions that may cause psychological discomfort at work. This study aims to determine the role of work-family balance, and quality of life to happiness at work in female correctional officers. The subjects in this study were 87 female correctional officers from three correctional institutions in Semarang and Malang. The age of subjects ranged from 22 - 57 years (Mage = 41.80); and the work period of the subjects ranged from 3-34 years (Mtenure = 18.80). The sampling technique used was convenience sampling. Instruments that used for data collection were demographic data questionnaires, Work-Family Balance Scale (32 items; α = .898), WHOQOL-BREF Scale (26 items; α = .906), and Happiness at Work Scale (22 items; α = .801). Data analysis using multiple regression analysis show there a positive and significant correlation between work-family balance and happiness at work (r = .613; p <.001), there was a positive and significant correlation between quality of life and work happiness (r = .394; p <.001), furthermore work-family balance and quality of life together can predict happiness at work in female correctional officers (r = .633; R2 = .401; F = 28.115; p <.001). Work-family balance and quality of life effectively contributed 39.7% to predicting happiness at work in female correctional officers.
Self-Retaining Freedom Proflor vs. Lichtenstein Mesh Repair for the Reduction of Postoperative Pain in Inguinal Hernia: A 1-Year Randomized Controlled Study
Authors: Rao Kannikanti Nageswara , Gogate A. S. 
Published: September 2019

Introduction: Lichtenstein tension-free mesh repair (LMR), surgical procedure for inguinal hernia, associated with postoperative pain. The study was aimed to compare self-retaining Freedom ProFlor versus LMR for the reduction of postoperative pain in inguinal hernia.Methodology: A total of 60 patients with inguinal hernia undergoing mesh repair were randomized into two groups of 30 each: group A (Freedom ProFlor mesh repair) and group B (LMR). Demographic data and clinical findings of all the patients including duration of pain, lump size, cough impulse, and the position of hernia were noted. Recorded findings such as postoperative pain and operative time were subjected to statistical analysis.Results: Most (31) of the patients had a hernia on the right side. The operative time was significantly less in group A when compared to group B (P < 0.05). Significantly lower pain scores were observed in group A than in group B (P < 0.05). The mean postoperative pain was significantly lower in group A compared with group B during the fifth follow-up visit (0.2 ± 0.41 vs. 1.07 ± 1.28; P < 0.0001). Conclusion: The Freedom ProFlor mesh repair was better than the LMR regarding postoperative pain. Moreover, the dose of the analgesic needed in the Freedom ProFlor mesh repair group was less and for a shorter time when compared to the LMR group. However, further long-term studies are required for documenting hernia recurrences.
Ontogenesis of Pelargonia sidoides (Geraniaceae) under greenhouse conditions
Authors: Gaidarzhy M. M. , Holubenko A. V. , Nuzhyna N. V. , Futorna O. A. , Senchylo O. O. 
Published: September 2019

The article presents the results of the ontogenesis study and complements the morphological description of the valuable medicinal plant Pelargonium sidoides, which is included in the Red List of Plants of South Africa, from the collection of succulents of the O. V. Fomin Botanical Garden. Unlike some species of the Pelargonium genus, which are stem succulents, P. sidoides is a succulent with thickened roots. It has been established that the pregenerative period lasts about 10 months, while the longest is the juvenile stage, during which plants form a large leafy series and begin to form thickened roots. The seedling stage in P. sidoides is much shorter than in many stem succulents with non-succulent leaves. Plants are cross-pollinated, in the conditions of cultivation they form a peduncle longer than in nature, up to 90 cm in length. Flowers are open to 6 days and during this time they undergo three consecutive stages: the opening of the anthers, an asexual pause, readiness of the pistil to be pollinated. Pollen grains are typical for representatives of the Pelargonium genus, but smaller, compared to pollen representatives of other sections. Fruits ripen in a short period 17–25 days, depending on the air temperature. The mericarps of P. sidoides differ in shape, colour and size from the mericarps of representatives of other genera of the Geraniaceae family, but the morphological characteristics of the seeds within the family are similar. The germ is located on the abdominal side of the seed; it occupies almost half of its volume and has clear outlines. According to its morphological features, P. sidoides leaves, as in most other species of the genus, have both mesomorphic and xeromorphic features. Analysis of the data gives ground for characterizing these plants as meso-xerophytes. P. sidoides quickly enters the generative period in the conditions of greenhouse cultivation and has high reproductive capacity.
Morphobiological analysis of Trichuris vulpis (Nematoda, Trichuridae), obtained from domestic dogs
Authors: Yevstafieva V. А. , Kravchenko S. O. , Gutyj B. V. , Melnychuk V. V. , Kovalenko P. N. , Volovyk L. B. 
Published: September 2019

The parasitic nematode Trichuris vulpis Frölich, 1789 is the pathogen of trichuriasis in domestic and wild carnivores, and humans. This helminth species is distributed world-wide in populations of domestic dog (Canis lupus familiaris). The prevalence of T. vulpis in dogs depends to a large degree on the morphofunctional and biological adaptations of the parasite which support its high survivability in various environmental conditions. The present study considers the species-specific peculiarities of morphology, and metric parameters of the mature and embryonic stages of Trichuris nematodes parasitizing in C. lupus familiaris. We studied the periods of stages of development and infectious egg formation, and their survivability under optimal conditions for T. vulpis in laboratory culture. The differential characteristics of both female and male adult T. vulpis nematodes include the metric characteristics of cuticular protrusions at the surface of the anterior body part. The male T. vulpis nematodes can be distinguished from males of other species by the specifics of spicule sheath ornamentation, the shape and size of spicule, and the width of spicule sheath at different sections. In identification of the female nematodes of this species, it is necessary to consider the presence and size of papillary processes in the vulval area and metric parameters of vulva location. Nine metric characters of sexual dimorphism are described for T. vulpis nematodes. In laboratory conditions, five embryonic stages were observed for T. vulpis: protoplast, blastomere cleavage, and formation of bean-like embryo, larva and mobile larva. These stages are characterized by specific morphological features. The egg develops to the infectious stage at 27 °С in 18 days of culture, and their survivability is up to 76.6%. The egg development is associated with changes in their metric characters, such as decreasing egg length and width of egg shell, and increasing egg width and egg plug width.
Physiological relationship between content of certain microelements in the tissues of different anatomic sections of the organism of honey bees exposed to citrates of argentum and cuprum
Authors: Kovalchuk I. , Dvylyuk I. , Lecyk Y. , Dvylyuk I. , Gutyj B. 
Published: September 2019

The study was conducted on honey bees of the Carpathian breed on the basis of the apiary of S. Z. Gzhytskyi Lviv National University of Veterinary Medicine and Biotechnologies. The bees were kept in 8-frame beehives with size of the frame of 435 × 300 mm. The study was undertaken in the summer-autumn period. A total of 5 groups of bee families were formed according to the analogue principle, with three families of bees in each group. Control (I) group received sugar syrup in 1 : 1 concentration (1000 mL/group/week). In the experimental (II) group, Ag was added to the syrup in amount of 0.5 mL/g of the sugar syrup; in III experimental group – in similar conditions Ag was added in 1 mg/L amount; IV group received sugar syrup with Cu in 0.5 mg/L amount; V experimental group – Cu in amount of 1 mg/L of sugar syrup. Microelements were added to sugar syrup in the form of citrates obtained using method of nanotechnology, developed by the company Nanomaterials and Nanotechnologies in Kyiv. The period of monitoring lasted 28 days with 7 days interval of preparation. Inter-group and anatomic differences were found in content of certain mineral elements in the tissues of the head, thorax and abdominal sections of the honey bees in conditions of feeding with citrates of argentum and cuprum in sugar syrups. Under the influence of citrate of argentum in amount of 0.5 and 1.0 mg/L of sugar syrup, content of ferrum increased in the tissues of the head and abdominal sections, though it decreased in the thorax, content of cuprum decreased in the tissues of head, thorax and abdomen, content of zinc increased in the tissues of head and thorax, though it decreased in the abdomen, content of lead and cadmium reduced in the tissues of all anatomic sections of the organism of honey bees. Under the influence of cuprum in amount of 0.5 and 1.0 mg/L of sugar syrup, content of ferrum reduced in the tissues of the head, though it increased in the tissues of thorax and abdomen, content of cuprum increased, and the content of zinc, lead and cadmium reduced in the tissues of all anatomic sections of honey bees. According to the results of the study, the determining effect of feeding of honey bees on the optimization of the parameters of mineral metabolism in different anatomic sections of the organism of bees is discussed.
X-ray densitometric indices of proximal phalanx, medial phalanx and ungular pelvic limb bones as criteria for age diagnosis of cattle in forensic veterinary expertise
Authors: Yatsenko I. V. , Tkachuk S. A. , Busol L. V. , Bondarevsky M. M. , Zabarna I. V. , Biben I. A. 
Published: September 2019

Morphological parameters of biological material are extremely informative in diagnostic studies, in particular, to determine the species, sex, time of death, the term of burial. The most informative object for these tasks is the skeleton, because changes in the bones are stored for a long time, while soft tissue is subjected to rotting. Bone tissue is the most durable, but at the same time, it is very labile and reacts to all metabolic processes in the body. The object of the study was proximal phalanx, medial phalanx and ungular bone of the pelvic limb of cattle ranging in age from newborn to 12 years old. Radiography of the proximal phalanx, medial phalanx and ungular bones of the pelvic limb was performed on the Arman apparatus. The bones were subjected to X-ray in the lateromedial projection. The inner and outer sections of the tubular bone were determined. The mathematical modeling of the interaction of X-rays and the cortical layer of bones of fingers (proximal phalanx, medial phalanx and ungular) of cattle was carried out in this work. It is established that this process is described by Bouger's law. The physico-mathematical model of proximal phalanx, medial phalanx and ungular bones has been calculated, on the basis of which it was possible to calculate the X-ray densitometric indices of these bones of cattle. The age features of dynamics of X-ray densitometric indices of the proximal phalanx, medial phalanx and ungular bones were established and a method of determining the age of cattle according to this criterion was proposed. A mathematical model for the proximal phalanx, medial phalanx and ungular bones of the pelvic limbs of cattle that can be applied in X-ray densitometry uses: for the average third proximal phalanx – section of heterogeneous tubular structure modeled by a semicircle; for a medial phalanx bone – a section of a triangular shape; for the ungular bone – a heterogeneous structure, the plantar surface is inscribed in a rectangle. The process of interaction of X-rays with the bone structure of the examined pelvic limb bones can be described by Bouguer's law. The developed mathematical modeling of this interaction and the algorithm for its analysis is the basis for determining the age of cattle for X-ray densitometric indices of the proximal phalanx, medial phalanx and ungular bones of pelvic limbs. By X-ray densitometry of the proximal phalanx and medial phalanx bones of the pelvic limbs extremities one can diagnose the age of bovine animals from birth to 5 years, but according to ungular bones – from birth to 10 years. X-ray densitometry of medial phalanx and ungular bones of pelvic limbs can be used for diagnosing bovine cattle in a complex with other morphological, chemical and physical methods of investigation.
Аrginase/NO-synthase system сharacteristics in blood lymphocytes under effect of fluoroquinolones
Authors: Кovalenko І. V. , Оnufrovych О. K. , Vorobets N. M. , Меlnyk О. V. , Vorobets Z. D. 
Published: September 2019

Antibiotics of the fluoroquinolone series are highly effective synthetic drugs of a wide range of antimicrobial activity. They have a specific mechanism of action on bacterial cells to inhibit the DNA-gyrase enzyme of mostly gram-negative and the topoisomerase IV of gram-positive bacterial cells, which leads to a decrease in the activity of enzymes, disruption of DNA and RNA biosyntheses, and the impossibility of chromosome superspilarization, as a result of which its division is broken and the cell dies. Fluoroquinolones also have an immunomodulatory effect, which is very important in terms of the pathogenesis of many infectious and inflammatory diseases. We assume that fluoroquinolones also act on cells of the body of patients, in particular on such regulatory mechanisms as the arginase-NO-synthase system. In this regard, peripheral blood lymphocytes can be a convenient and adequate model for studying the mechanism of the effect of fluoroquinolones. It is shown that under the influence of various generations of fluoroquinolones, arginase activity increases, depending on the dose, in the following sequence: control → ciprofloxacin → levofloxacin → moxifloxacin. The highest activity is observed under the effects of moxifloxacin, belonging to generation IV. The increase in arginase activity in blood lymphocytes under the influence of fluoroquinolones occurs due to the growth of turnover number of the enzymes (Vmax increases), although the affinity of enzyme to the substrate decreases (KL-arg increases). At the same time, all fluoroquinolones reduce the activity of the constitutive isoforms of NO-synthase, depending on the dose. It has been established that a slight activity of iNOS of blood lymphocytes in practically healthy women was detected, almost on the verge of error. When studying the influence of fluoroquinolones on the activation of iNOS lymphocytes isolated from the blood of practically healthy women, we did not observe its activity, and the inhibitive effect could not be determined due to its low activity. Oxidative stress was used to induce iNOS activity in blood lymphocytes, with H2O2 lymphocytes preincubation. The preincubation of lymphocytes with 0.2 mM H2O2 leads to increase of iNOS activity by 31.30 times. By activation of iNOS with hydrogen peroxide, 10–5 M concentration of ciprofloxin leads to inhibition of enzyme activity by 1.22 times, levofloxacin by 1.45 and moxifloxacin by 2.34 times. The obtained kinetic parameters suggest that in the blood lymphocytes under the influence of fluoroquinolones, the synthesis of NO with the participation of cNOS is inhibited, and the hyperproduction of NO is inhibited by the activation of iNOS, which is characteristic for pathological conditions.
Influence of chromium citrate on oxidative stress in the tissues of muscle and kidney of rats with experimentally induced diabetes
Authors: Sushko О. О. , Iskra R. J. , Ponkalo L. I. 
Published: September 2019

Chromium is one of the important trace elements that is essential for carbohydrate, protein and lipid metabolism. Chromium improves glucose metabolism and reduces insulin resistance due to increased insulin sensitivity. Therefore, it is important to consider the use of chromium citrate as a nutritional supplement with potential hypoglycemic and hypolipidemic effects. In this research work, we investigated the activity of the antioxidant system and the level of lipid hydroperoxides in the tissues of skeletal muscles and kidneys of experimental diabetic rats and for rats which received in their daily diet chromium citrate in the amounts 0.1 and 0.2 μg/mL of water. We induced the experimental model of diabetes by intraperitoneal injection of alloxan in the amount 150 mg/kg of body weight of the animals. We monitored glucose levels by measuring daily glucose levels with a portable glucose meter. For research, we selected animals with a glucose level > 11.1 mmol/L. We monitored the body weight of rats. On the 40th day of the study, we withdrew the animals from the experiment by decapitation. We selected the tissue for research, namely skeletal muscles and kidneys. In samples of the tissue homogenates, we measured the activity of antioxidant enzymes and the content of lipid peroxide oxidation products. As a result of our research, we found that the products of lipid peroxide oxidation and glutathione peroxidase activity increased in skeletal muscle of animals with diabetes mellitus. The activity of glutathione reductase, catalase, superoxide dismutase, and the content of reduced glutathione decreased at the same time. In the kidneys of diabetic rats, the activity of glutathione peroxidase, glutathione reductase, catalase and content of lipid hydroperoxides increased but the activity of superoxide dismutase and the content of reduced glutathione decreased. The addition of chromium citrate to the diet of animals in amounts 0.1 and 0.2 μg/mL led to the suppression of oxidative stress. The activity of catalase, glutathione peroxidase and the content of lipid hydroperoxides, TBA-positive substances decreased. Also, the activity of superoxide dismutase increased with the addition of chromium citrate. These results indicate normalization of antioxidant defense in the skeletal muscle and kidneys of experimental rats with experimental diabetes given chromium citrate in the amount 0.1 mg/mL of water.
Interdependence of oxidative/antioxidant system indicators and thyroid status under conditions of prolonged exposure to small doses of radiation
Authors: Sokolenko V. L. , Sokolenko S. V. 
Published: September 2019

We have studied the interdependence of the intensity of oxidative processes/antioxidant level and the thyroid status parameters in a group of students aged 18–24 who lived for a long time in the territory of enhanced radioecological control (density of soil contamination by isotopes (137Cs 3.7 ∙ 104 – 18.5 ∙ 104 Bq/m2). We examined 50 people from relatively environmentally friendly areas (control group) and 50 people from IV radiation zone (experimental group). In the experimental group, there were no individuals with clinical manifestations of thyroid pathology. However, subgroups with signs of hyperthyroidism and hypothyroidism were identified. We evaluated the level of cortisol, thyrotrophic hormone (TSH), triiodothyronine (T3), thyroxine (T4), malonic dialdehyde (MDA), ceruloplasmin (CP), transferrin (Tf), sulfhydryl groups (SH); we calculated the oxidative stress index (OSI). The research was conducted one month before the examination time and also during the exams as a factor in increased emotional stress. A lowered CP level was found in the subgroup with signs of hypothyroidism; SH groups – in all subgroups, separated by thyroid status. The oxidative stress index was higher in all students examined of the experimental group, compared with the control. The growth of MDA level is marked in the experimental group – it is the most strongly pronounced in conditions of additional emotional load in people with signs of hyperthyroidism and hypothyroidism. CP level significantly decreased in the subgroup of hyperthyroidism on the background of T3 decrease. OSI increased in all students examined from the experimental group. In the subgroup of hypothyroidism it became significantly higher than in the subgroup of euthyroidism. A positive correlation between the levels of CP and T3 was found. The highest values of the correlation coefficients were noted for subgroups with signs of hyperthyroidism and hypothyroidism, with the coefficient significance increasing under conditions of emotional stress. The index of oxidative stress in the experimental group positively correlated with the level of TSH – in terms of emotional stress, the statistical significance of the coefficients disappeared. In the subgroups divided by thyroid status, variability of interactions between OSI and T3 was observed but it was not statistically significant. It was found that the participation of thyroid status in supporting redox homeostasis in people aged 18–24 who suffered from chronic small-doze radiation exposure was realized mainly by the influence on the antioxidant system. The ability of thyroid hormones to maintain a proper antioxidant state was suppressed in this group. The unbalanced relationship between thyroid hormones and oxidative stress indicators is strongly manifested under conditions of additional emotional stress.