bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Digital Twin Framework Utilizing Machine Learning for Robust Predictive Maintenance: Enhancing Tire Health Monitoring
Authors: Karkaria Vispi , Chen Jie , Luey Christopher , Siuta Chase , Lim Damien , Radulescu Robert , Chen Wei 
Published: November 2024

Abstract
We introduce a novel digital twin (DT) framework for predictive maintenance of long-term physical systems. Using monitoring tire health as an application, we show how the DT framework can be used to enhance automotive safety and efficiency, and how the technical challenges can be overcome using a three-step approach. Firstly, for managing the data complexity over a long operation span, we employ data reduction techniques to concisely represent physical tires using historical performance and usage data. Relying on these data, for fast real-time prediction, we train a transformer-based model offline on our concise dataset to predict future tire health over time, represented as Remaining Casing Potential (RCP). Based on our architecture, our model quantifies both epistemic and aleatoric uncertainty, providing reliable confidence intervals around predicted RCP. Secondly, to incorporate real-time data, we update the predictive model in the DT framework, ensuring its accuracy throughout its life span with the aid of hybrid modeling and the use of discrepancy function. Thirdly, to assist decision making in predictive maintenance, we implement a Tire State Decision Algorithm, which strategically determines the optimal timing for tire replacement based on RCP forecasted by our transformer model. This approach ensures our DT accurately predicts system health, continually refines its digital representation, and supports predictive maintenance decisions. Our framework effectively embodies a physical system, leveraging big data and machine learning (ML) for predictive maintenance, model updates, and decision-making.
Tetrascatt Model: Born Approximation for the Estimation of Acoustic Dispersion of Fluid-Like Objects of Arbitrary Geometries
Authors: Lavia Edmundo F. , Gonzalez Juan D. , Cascallares Guadalupe 
Published: November 2024

Abstract
Modeling the acoustic scattering response due to penetrable objects of arbitrary shapes, such as those of many marine organisms, can be computationally intensive, often requiring high-performance computing equipment when considering a completely general situation. However, when the physical properties (sound speed and density) of the scatterer are similar to those of the surrounding medium, the Born approximation provides a computationally efficient way to calculate it. For simple geometrical shapes like spheres and spheroids, the acoustic scattering in the far field evaluated through the Born approximation recipe results in a formula that has been historically employed to predict the response of weakly scattering organisms, such as zooplankton. Further, the Born approximation has been extended to bodies whose geometry can be described as a collection of noncircular rings centered on a smooth curve. In this work, we have developed a numerical approach to calculate the far-field backscattering by arbitrary 3D objects under the Born approximation. The object's geometry is represented by a volumetric mesh composed of tetrahedrons, and the computation is efficiently performed through analytical 3D integration, yielding a solution expressed in terms of elementary functions. On a current desktop PC the model can compute the scattering from meshes with millions of elements in a matter of minutes. This model is able to compute the scattering from a complex shape 200× faster than other methods like the Boundary Element Method, without compromising the numeric quality of the solution. The method's correctness has been successfully validated against benchmark solutions. Additionally, we present acoustic scattering results for species with complex geometries. To enable other researchers to use and validate the method, a computational package named tetrascatt was developed in the R programming language and published in the CRAN (Comprehensive R Archive Network).
Generation of Cu-Au skarn mineralization by mafic magma recharge: Insights from the Bozymchak deposit in the Chatkal-Kurama region, Kyrgyzstan, West Tianshan
Authors: Zu Bo , Zhang Hao , Chi Guoxiang , Wang Rui , Seltmann Reimar , Williams-Jones A.E. , Pak Nikolay , Xue Chunji 
Published: November 2024

Large numbers of igneous intrusions are emplaced in the magmatic arcs above subduction zones, but only a small fraction of them are mineralized with Cu ± Au ± Mo. Despite significant advances in recognizing the importance of magma source, volatile content, and redox condition in controlling mineralization, the magmatic processes required to form a mineral deposit are still poorly understood. Here, we demonstrate that mafic recharge to the magma chamber is critical for Cu-Au mineralization, as exemplified by the Bozymchak Cu-Au skarn deposit in the Chatkal-Kurama arc of Kyrgyzstan, West Tianshan. The Bozymchak intrusion associated with the mineralization comprises monzonite porphyry and granodiorite porphyry. A sensitive high-resolution ion microprobe zircon U-Pb age of 305 ± 2 Ma was obtained for the monzonite porphyry, which is consistent with the U-Pb age of zircon from the granodiorite porphyry (304 Ma) and an Re-Os age for the molybdenite (305 Ma). These ages indicate that both the monzonite porphyry and granodiorite porphyry were coeval with mineralization. The monzonite porphyry exhibits high-K calc-alkaline (K2O = 3.36−3.50 wt%), metaluminous and magnesian-rich characteristics, enrichment in large ion lithophile elements (LILEs; e.g., Cs, Th, Ba, K, and Pb), and negative anomalies in high field strength elements (HFSEs; e.g., Nb, Ta, and Ti). These geochemical signatures, combined with the Sr-Nd-Hf isotopic signatures [ISr(avg) = 0.7059, εNd(t) = −3.5 to −2.8, εHf(t) = −3.8 to +1.4], suggest that the magma was the product of partial melting of a metasomatized mantle wedge and was subjected to subsequent assimilation and fractional crystallization (AFC).
The development of disequilibrium textures in both the monzonite porphyry and the granodiorite porphyry, such as acicular apatite, reverse zoning of plagioclase, and coexisting high-Al and low-Al amphiboles, indicates that the magma evolved in an open crustal magma chamber with mafic magma recharge. The magmas were moderately oxidized (∼ΔFMQ +1.0; FMQ is the fayalite-magnetite-quartz oxygen buffer) and water-rich, with 5.9 wt% and 6.5 wt% H2O in the granodiorite porphyry and monzonite porphyry, respectively. The repeated influx of hot mafic magma batches prolonged the existence of the magma chamber and promoted the maturation of the arc magma. In addition to introducing more Cu and Au, the replenishment of mafic magma in the chamber also introduced additional H2O and Cl, as shown by the presence of high-Al amphiboles and the elevated oxygen fugacity, which further promoted Cu-Au mineralization.
Simultaneous Calculation of Chemical and Isotope Equilibria Using the GEOCHEQ_Isotope Software: Iron Isotopes
Authors: Polyakov V. B. , Mironenko M. V. , Alenina M. V. 
Published: November 2024

Abstract—
The GEOCHEQ_Isotope software package, previously developed to calculate chemical and isotopic equilibria of carbon and oxygen in hydrothermal and hydrogeochemical systems by minimizing Gibbs energy, was extended to the simultaneous calculation of isotopic effects of carbon, oxygen, and iron (the main objective of the study). As for carbon and oxygen, the β-factor formalism was used to develop algorithms and a database for the calculation of iron isotopic effects. According to the developed algorithm, the Gibbs energy G*(P, T) of formation of a rare isotopologue was calculated through the Gibbs energy of formation of the main isotopologue taking into account the value of the 56Fe/54Fe β-factor of this substance and the mass ratio of 54Fe and 56Fe isotopes. The approximation of ideal isotope mixture was used. The temperature dependence of the β-factor is unified in the form of a third-order polynomial by inverse even degrees of absolute temperature. Based on a critical analysis of currently available data on equilibrium isotopic factors obtained by different methods (elastic and inelastic γ-resonance scattering, isotope exchange experiments, and ab-initio calculations), the main result was obtained: for the first time, internally consistent database on iron β-factors of minerals and water complexes was developed. To develop the database, minerals and aqueous complexes for which the estimates of the equilibrium fractionation factors of iron isotopes obtained by different methods exist and consistent within the error of the methods have been identified: metallic iron (α-Fe), hematite, magnetite, siderite, pyrite, and the aqueous complexes $${\text{Fe(III)(}}{{{\text{H}}}_{{\text{2}}}}{\text{O)}}_{6}^{{3 + }}$$ and $${\text{Fe(III)(}}{{{\text{H}}}_{{\text{2}}}}{\text{O)}}_{6}^{{2 + }}$$. The values of the iron β-factors for these minerals and aqueous complexes, accepted as reference ones, formed the “mainstay” of the developed database. Considering that the equilibrium isotopic shifts of iron between minerals and water complexes are estimated much more accurately within the framework of one method rather than the corresponding β-factors, the database was made consistent by linking the ln β values for minerals and water complexes to the reference ln β values. The application of the GEOCHEQ_Isotope software package to the closed carbonaceous hydrothermal system H2O–CO2–Fe2O3–FeO–CaO (T = 200°C, P = 16–50 bar) has shown the possibility of its use for the calculation of changes in mineral composition and isotopic effects on oxygen, carbon, and iron.
Optimized battery electrodes with primer layers by simultaneous two-layer slot-die coating
Authors: Hoffmann Alexander , Klemens Julian , Raupp Sebastian , Hanske Christoph , Lawrenz Nils , Machate Michael , Scharfer Philip , Schabel Wilhelm 
Published: November 2024

AbstractMulti-layer coating is a promising method for optimizing the properties of battery electrodes. This study examines the simultaneous coating of anodes with a primer layer without the necessity of a second coating and drying step, as it is the case for sequential coating processes. The primer layer is used to concentrate the binder in proximity to the substrate, thereby enhancing the adhesion strength of the electrode. Two systems comprising anode and primer, differing in rheological properties, are selected for coating investigation. It is demonstrated that the viscosity ratio of the multi-layer coating has a pronounced effect on coating suitability. In a two-layer system, the viscosity ratio also changes with shear rate due to the possibly different shear thinning properties. This results in the observation that combinations with strong viscosity ratios might only be stable in specific coating speed ranges. In contrast, combinations with moderate viscosity ratios exhibit a reduction in stable process windows as the viscosity ratio between the top and bottom layer increases. A mechanical characterization of the adhesion strength of dried and calendered electrodes demonstrated a notable enhancement in adhesion strength when a primer was utilized. In addition, capacity retention tests revealed that the electrochemical properties were not adversely affected by the primer.
Determinants of Visceral Leishmaniasis in Addis Zemen Health Center, Northwest Ethiopia
Authors: Gedamu Atsedemariam Nigus , Andargie Asrat Atsedeweyn , Aguade Aragaw Eshetie , Tezera Samuel Derso 
Published: November 2024

Background: Visceral leishmaniasis (VL) is one of the public health issues in some areas of Ethiopia, and over 3.2 million people are at risk with an estimated 4000 new cases occurring each year in the country. This study was conducted to determine the prevalence of VL and its associated risk factors in Addis Zemen Health Center, Northwest Ethiopia.Methods: Data were collected from Addis Zemen Health Center and meteorological office in Addis Ababa from 2012 to 2016. Univariate and multivariate analyses were conducted to identify the determinants of VL. According to the result obtained from the retrospective data analysis, a total of 4100 suspected VL patients diagnosed by rk39 in Addis Zemen Health Center from Libokemkem and nearby districts.Results: The overall prevalence of VL among study participants were 30% (1230/4100). Of this, the prevalence of VL among male and female study participants was 86.8% and 13.2%, respectively. The proportion of sex infected by VL was 3.26 times higher in male than female (AOR = 3.26, 95% CI: 2.42–4.40). The risk of acquiring VL in those people living in rural area was 62% more likely than those residing in urban (AOR = 1.62, 95% CI: 1.29–2.04). People that were traveled to the endemic area of VL were 18.44 times more likely to be affected than the people who have not traveled once (AOR = : 18.44, 95% CI: 14.49–23.47). Age, sex, residence, season, travel history to endemic areas, and mean monthly precipitation were found to be statistically significant for VL at 5% significance level.Conclusion and Recommendation: The prevalence of VL in the present study was high with the highest prevalence in the rural areas. Therefore, there is a need of the immediate establishment of sound control and prevention program in rural areas.
Breast Cancer Subtype–Specific Organotropism Is Dictated by FOXF2-Regulated Metastatic Dormancy and Recovery
Authors: Jiang Wen-Jing , Zhou Tian-Hao , Huang Huan-Jing , Li Lin-Sen , Tan Hao , Zhang Rui , Wang Qing-Shan , Feng Yu-Mei 
Published: November 2024

Abstract
Breast cancer subtypes display different metastatic organotropism. Identification of the mechanisms underlying subtype-specific organotropism could help uncover potential approaches to prevent and treat metastasis. In this study, we found that forkhead box F2 (FOXF2) promoted the seeding and proliferative recovery from dormancy of luminal breast cancer (LumBC) and basal-like breast cancer (BLBC) cells in the bone by activating the NF-κB and BMP signaling pathways. FOXF2 promoted LumBC cell seeding but not proliferative recovery in the lung by activating the BMP signaling pathway. Conversely, FOXF2 suppressed the seeding and proliferative recovery of BLBC cells in the lung by repressing the TGFβ signaling pathway. FOXF2 directly upregulated RelA/p65 transcription and expression in LumBC and BLBC cells by binding to the RELA proximal promoter region and RelA/p65 bound to the FOXF2 proximal promoter region to upregulate expression, forming a positive feedback loop. Targeting the NF-κB pathway efficiently prevented the metastasis of FOXF2-overexpressing breast cancer cells to the bone, whereas inhibiting TGFβ signaling blocked the metastasis of BLBC with low FOXF2 expression to the lung. These findings uncover critical mechanisms of breast cancer subtype–specific organotropism and provide insights into precision assessment and treatment strategies.
Significance: FOXF2 regulates signaling pathways in a subtype-specific manner to coordinate the fate of disseminated breast cancer cells in distant organs, suggesting that FOXF2 functions could be harnessed to prevent organ-specific metastasis.
See related commentary by Bado, p. 639
Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies
Authors: Haffner Michael C. , Morris Michael J. , Ding Chien-Kuang C. , Sayar Erolcan , Mehra Rohit , Robinson Brian , True Lawrence D. , Gleave Martin , Lotan Tamara L. , Aggarwal Rahul , Huang Jiaoti , Loda Massimo , Nelson Peter S. , Rubin Mark A. , Beltran Himisha 
Published: November 2024

Abstract
Lineage plasticity and histologic transformation from prostate adenocarcinoma to neuroendocrine (NE) prostate cancer (NEPC) occur in up to 15% to 20% of patients with castration-resistant prostate cancer (CRPC) as a mechanism of treatment resistance and are associated with aggressive disease and poor prognosis. NEPC tumors typically display small cell carcinoma morphology with loss of androgen receptor (AR) expression and gain of NE lineage markers. However, there is a spectrum of phenotypes that are observed during the lineage plasticity process, and the clinical significance of mixed histologies or those that co-express AR and NE markers or lack all markers is not well defined. Translational research studies investigating NEPC have used variable definitions, making clinical trial design challenging. In this manuscript, we discuss the diagnostic workup of metastatic biopsies to help guide the reproducible classification of phenotypic CRPC subtypes. We recommend classifying CRPC tumors based on histomorphology (adenocarcinoma, small cell carcinoma, poorly differentiated carcinoma, other morphologic variant, or mixed morphology) and IHC markers with a priority for AR, NK3 homeobox 1, insulinoma-associated protein 1, synaptophysin, and cell proliferation based on Ki-67 positivity, with additional markers to be considered based on the clinical context. Ultimately, a unified workup of metastatic CRPC biopsies can improve clinical trial design and eventually practice.
Purity of Faith, Madhhab Partisanship, and Legitimising Ideology in the Great Seljuq Sultanate
Authors: Tor D.G. 
Published: November 2024

Abstract
The madhhab is usually investigated from the standpoint of fiqh. But there was also a social aspect to the importance of the madhhab, which at no time played a more crucial social role than during the Seljuq period (1040–1194). In particular, Ḥanafī madhhab affiliation became both the post-conquest ideological justification for Seljuq rule, and the glue holding together the two elements of the Seljuq ruling class: The Turkish magnates and the Khurasani bureaucrats. This article proves three points: First, that the original Seljuq conquest neither looked like nor purported to be the religious mission the Seljuqs later claimed it was; second, it traces the post-facto madhhab-based justification of their rule which the Seljuqs adopted, and its success in obtaining Khurasani support for the Seljuq regime; and, finally, it shows also the negative consequences this ideology of partisan Ḥanafism had on the internal peace of their realm and its urban flourishing.
All the Dead Boys Look Like Me
Authors: Lalude Olalekan Moyosore 
Published: November 2024

Abstract
Nigeria criminalised same sex marriages in 2014 which put a state approval to homophobic violence and discrimination. Just in 2021, Ghana made a similar and even more dangerous move towards homophobia when its parliament had a bill proposed towards the criminalisation of the advocacy for gay people and would legitimise prosecution of the members of the lgbt+. These developments have left sexual minorities vulnerable by making them open to attacks from homophobic people and creating institutionalised discrimination. Through a phenomenological research approach, this study would examine how legal frameworks influence the recognition and protection of rights for sexual minorities in Ghana and Nigeria. Unstructured interviews with members of the lgbt and human rights advocates would be conducted both in Nigeria and Ghana. Content analysis, especially conceptual analysis, would be done on the Constitution of the Republic of Ghana 1992 and the Constitution of the Federal Republic of Nigeria, human rights norms, journal articles and other secondary materials. This study would conclude that homophobia cedes state agency to non-state actors and undermines the right to life as protected in the Ghanaian and Nigerian constitutions. Strategies for advocacy against homophobia and for the protection of the rights of sexual minorities would be recommended.
Baptist and Catholic? Tradition and Authority in the Baptist Theology of Stephen R. Holmes
Authors: Fellows Philip 
Published: November 2024

Abstract
This article begins by analysing the principles at the heart of Stephen R. Holmes’ vision of Baptist theology and ecclesiology. It then examines Holmes’ work on the authority of theological Tradition. It is demonstrated that Holmes argues for a pneumatologically rooted and consensual understanding of Tradition that locates its authority in the testimony of the whole church to the voice and will of the Spirit interpreting the texts he inspired. In the final third of the argument, these two areas of Holmes’ work are brought into dialogue to generate an authentically Baptist conception of the authority of Tradition to bind the local church. It is suggested that this can help Baptists and others holding to some form of congregational church government resolve issues in their commitment to the catholicity and unity of the Church, provide a more secure ground for theological discernment, and enable more fruitful ecumenical dialogue.
Constructions of Religion in Swedish Newspaper Articles on Funerals during the covid-19 Pandemic
Authors: Jarnkvist Karin 
Published: November 2024

Abstract
This study examines the discursive construction of religion in Swedish newspaper articles on funerals during the covid-19 pandemic. Thirty articles from the six most prominent newspapers were analyzed using Multimodal cda and intersectionality. Most articles deal with religion as an institution, followed by religion as a group and individual religiosity. Religion is constructed in intersection with ethnicity and gender. The CoS is privileged, portraying Lutheran Christians as professionals. Minority religions are positioned as ‘the other’, something ‘problematic’ or ‘different’ from ‘Swedish (secular) values’ and ways of living. Migrant men and women are portrayed stereotypically. However, alternative narratives are told by well-educated and influential representatives of different minority religions, giving these religions a ‘voice’. I argue that increased religious literacy is needed among media workers if the reporting should be based on equality within and between the power categories of gender, ethnicity, and religion.
Dispute Resolution in the AfCFTA Investment Protocol: a Preliminary Assessment and Proposal for Business and Human Rights Arbitration
Authors: Ogunranti Akinwumi 
Published: November 2024

Abstract
This paper examines whether the Investment Protocol to the African Continental Free Trade Area (AfCFTA) Agreement aligns with international human rights law’s (IHRL) standards on the right to equality, non-discrimination, and access to an effective remedy. It argues that the Protocol’s dispute resolution model, which tilts towards ISDS, is incompatible with IHRL. This paper recommends incorporating the Hague Rules on Business and Human Rights Arbitration (Hague Rules) into the Protocol to create an IHRL-compatible dispute system, especially regarding enforcing human rights, environment, and climate obligations against investors and states. As African countries finalize the annex to the Protocol, they must replace ISDS with a BHR Arbitration framework as the dispute settlement regime within which investment players must enforce their rights.