bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are Minimum Wages a Silent Killer? New Evidence on Drunk Driving Fatalities
Authors: Sabia Joseph J. , Pitts M. Melinda , Argys Laura M. 
Published: July 2018

AbstractIn volume 94 of this REVIEW, Adams, Blackburn, and Cotti (ABC), using Fatal Accident Reporting System data from 1998 to 2006, find that a 10% increase in the minimum wage is associated with a 7% to 11% increase in alcohol-related fatal traffic accidents involving teen drivers. We find this result does not hold when the analysis period is expanded to include 1991 through 2013. In addition, auxiliary analyses provide no support for income-driven increases in alcohol consumption, the primary mechanism posited by ABC. Together, our results suggest that minimum wage increases are not a silent killer.
Locating the Study of Religion in a Theory of the Academy
Authors: Woll Donald Bruce 
Published: July 2018

AbstractThe central claim of this article is that Jonathan Z. Smith, in addition to his extensive contributions to the study of religion, makes a valuable contribution to the theory and responsible public exercise of cognitive power. This larger public concern is explicitly and repeatedly addressed in his writings on the academy in which he develops a theory of the academy that articulates the conditions essential to the responsible exercise of cognitive power. A further claim is that this theory constitutes the integrating standpoint of his study of religion. The failure to recognize the relationship between his theoretical writings on the academy and his study of religion, reflecting his two careers, has given rise to misunderstandings that have obscured the wider public significance of his entire oeuvre.
Comparing CLIGEN-Generated Storm Patterns with 1-Minute and Hourly Precipitation Data from China
Authors: Wang Wenting , Yin Shuiqing , Flanagan Dennis C. , Yu Bofu 
Published: July 2018

AbstractClimate Generator (CLIGEN) is a stochastic weather generator that has been widely used to generate daily precipitation and storm patterns for hydrological and erosion prediction models. Rainfall data with measurement intervals ≤ 30 min are required to compute two parameters for generating storm patterns, namely, the cumulative distribution of the time to peak rainfall intensity (TimePk) and the mean daily maximum 30-min rainfall intensity (MX.5P). High-resolution rainfall data, however, are not widely available around the world. One-minute precipitation data for 18 stations in eastern and central China were aggregated into hourly intervals to evaluate methods to optimally prepare TimePk and MX.5P for CLIGEN. Four sets of the two parameters were used to run CLIGEN for comparison: C0, using the original 1-min data; C1, replacing TimePk with those computed with hourly data; C2, replacing MX.5P with those computed with hourly data with an adjustment factor; and C3, replacing both parameters with those computed with hourly data, and the MX.5P was adjusted as for C2. Results showed that 1) MX.5P computed with hourly data was systematically lower than that computed with the 1-min data, and the bias could be corrected by multiplying by an adjustment factor of 1.40; 2) the difference in generated storm patterns between C0 and C1 was insignificant; and 3) results from C2 and C3 agreed well with those generated from C0. Hourly precipitation data can be used to prepare CLIGEN input parameter values for generating storm patterns for sites where only hourly data are available.
Available Potential Energy in Density Coordinates
Authors: Colin de Verdière Alain , Huck Thierry , Pogossian Souren , Ollitrault Michel 
Published: July 2018

AbstractThe vertically integrated potential energy of an incompressible stratified fluid formulated in density coordinates can be simply written as a weighted vertical sum of the squares of the vertical displacements of density surfaces, a general expression valid for arbitrary displacements. The sum of this form of potential energy and kinetic energy is then a conserved quantity for the multilayer shallow water model. The formulation in density coordinates is a natural one to find the Lorenz reference state of available potential energy (APE). We describe the method to compute the APE of an ocean state and provide two applications. The first is the classical double-gyre, wind-driven circulation simulated by a shallow water model at high resolution. We show that the eddy kinetic and eddy potential energies are localized in regions of large gradients of mean APE. These large gradients surround an APE minimum found between the two gyres. The second is the time-mean World Ocean Circulation reconstructed from hydrography (World Ocean Atlas) and reference velocities at 1000 db from the Argo float program to obtain an absolute circulation. The total available potential energy exceeds the total mean kinetic energy of the World Ocean by three orders of magnitude, pointing out the very small Burger number of the circulation. The Gulf Stream, the Kuroshio, the Agulhas retroflection, and the confluence regions are four examples that confirm the shallow water model results that large gradients of mean available potential energy can be used as predictors for the presence of high eddy kinetic energy (obtained here from satellite altimetry).
Empathic profile of nursing freshmen
Authors: Mendes Isabel Amélia Costa , Trevizan Maria Auxiliadora , Souza Mirella Castelhano , Souza-Junior Valtuir Duarte , de Godoy Simone , Ventura Carla Aparecida Arena , Santos Sara Soares dos 
Published: July 2018

Objective: To analyze the empathic profile and the empathy scores of freshmen of the nursing course. Design and participants: Descriptive study involving 399 freshmen students of two modalities of nursing courses: Bachelor and Bachelor and Teaching Diploma, in the period from 2012 to 2015. A sociodemographic questionnaire and the Empathy Inventory were applied. Ethical considerations: The research received approval from the Research Ethics Committee of the University of São Paulo at Ribeirão Preto College of Nursing. The students registered their acceptance to participate in the research by signing the Free and Informed Consent Form and anonymity was guaranteed. Findings: The mean age of the participants was 19 years, being 85.5% female. The students were grouped by course modality and all groups presented high empathy scores. A significant difference (p < 0.001) was found, which indicates that students of the Bachelor and Teaching Diploma program presented a higher degree of empathy for the General Score, Domain 2 (Interpersonal Flexibility), and Domain 3 (Altruism) in relation to students in the Bachelor program. Conclusion: Results show that nursing undergraduate freshmen are emphatic, with minimum differences between the two courses. This profile is relevant for the development of future professionals capable to demonstrate a balance between instrumental and expressive competences.
Incidence and demographics of 1751 surgically treated periprosthetic femoral fractures around a primary hip prosthesis
Authors: Chatziagorou Georgios , Lindahl Hans , Garellick Göran , Kärrholm Johan 
Published: July 2018

Introduction: Periprosthetic femoral fractures (PPFF), treated surgically, have been recorded in the Swedish Hip Arthroplasty Register (SHAR) since 1979. It is postulated that fractures treated with other methods other than stem revision have a lower registration rate, which may lead to incomplete registry data and thus, inaccurate information. We collected all PPFFs surgically treated in Sweden between 2001 and 2011 with the purpose of studying the annual incidence, demographics and distribution of fracture types with regard to type of fixation. Methods: Data was linked between the SHAR and the National Patient Register (NPR) in order to detect even those PPFFs not reported to the SHAR. Fractures were classified according to the Vancouver classification system, based on information collected from the medical charts. This procedure was validated with observer variation analysis compared to fracture classification based on radiographs. In total 1751 first-time PPFFs around primary conventional stems were included. Results: The incidence of PPFF increased from about 1.0 per 1000 primary THRs to 1.4. Vancouver type C fractures (37% of all fractures) were more common than previously reported, and more common in cemented than in uncemented stems. The 3 most common stem designs involved were Exeter polished, Lubinus SPII, and Charnley (66.3% of all stems), partly reflecting their occurrence in the Swedish THR population. Discussion: The incidence of PPFFs has increased in Sweden during the period 2001 to 2011. The improved reporting of type C fractures, after data-linking, revealed an almost 4 times higher incidence compared to previous register studies in Sweden.
Information and communication technology use in daily life among young adults with mild-to-moderate intellectual disability
Authors: Ramsten Camilla , Martin Lene , Dag Munir , Hammar Lena Marmstål 
Published: July 2018

Background: Information and communication technology (ICT) increases participation in life activities, and young adults are frequent users. Young adults with intellectual disability (ID) do not use ICT as much as their peers, and little is known about how ICT is used by young adults with ID. This study describes the use of ICT from the perspective of young adults with mild to moderate ID in a municipal social care context. Method: Semi-structured interviews were used to collect information from 11 young adults with mild-to-moderate ID living in residential care and analysed using a content analysis. Results: ICT was used for family relationships, daily support, interactions based on interests and amusement, and as support for offline activities. Family members were important providers of support for ICT use. Conclusion: Young adults with mild-to-moderate ID use ICT in their daily life. The social care context needs to be further investigated due to its influence on the young adults’ access to ICT and need of support.
Strategies for Successful Survivorship Care Plan Implementation: Results From a Qualitative Study
Authors: Birken Sarah A. , Clary Alecia S. , Bernstein Shampa , Bolton Jamiyla , Tardif-Douglin Miriam , Mayer Deborah K. , Deal Allison M. , Jacobs Sara R. 
Published: July 2018

Introduction: Care for US cancer survivors is often fragmented, contributing to poor health outcomes. Care and outcomes may improve when survivors and follow-up care providers receive survivorship care plans (SCPs), written documents containing information regarding cancer diagnosis, treatment, surveillance plans, and health promotion. However, implementing SCPs is challenging. As such, we sought to identify strategies for successfully implementing SCPs. Methods: We measured SCP implementation using performance data from cancer programs participating in the American Society of Clinical Oncology Quality Oncology Practice Initiative, an oncologist-led quality assessment and improvement program. We used semistructured interviews with cancer program employees (eg, physicians) to identify strategies for successfully implementing SCPs by comparing approaches in cancer programs that, according to Quality Oncology Practice Initiative performance indicators, developed and delivered SCPs to a relatively small proportion of eligible survivors and their follow-up care providers (ie, low performers; n = 6 participants in five programs) with approaches among programs with better performance (ie, moderate performers; n = 15 participants in nine programs). Results: Ten of 14 cancer programs developed SCPs for ≥ 50% of eligible survivors; two of 14 delivered SCPs to any survivors; and eight of 14 delivered SCPs to ≥ 25% of follow-up care providers. We found that moderate performers proactively addressed SCP requirements, leveraged requirements to improve survivorship care, set internal targets, automated implementation, had active leaders and champions, and tasked appropriate employees with SCP implementation. Conclusion: SCP implementation remains challenging. We identified strategies for successfully implementing SCPs. Future research should examine how cancer programs have achieved these strategies; findings could contribute to an understanding of the changes needed to implement comprehensive survivorship care.
Presidential Address: Eighteenth-Century Indian Trading Villages in the Wabash River Valley
Authors: Sleeper-Smith Susan 
Published: July 2018

AbstractIn the eighteenth-century western Great Lakes, the French and British established forts to guard a highly profitable fur trade. Places like Fort Michilimackinac became synonymous with the fur trade. In warmer regions an equally profitable Indian-controlled fur trade also took place. This article examines the Wabash River valley trade and shows how two Indian villages, Kethtippecanuck and Miamitown, dominated the exchange process. Economics and sociability were intertwined in this flourishing region. Trade took place between friends and relatives, defined by the reciprocity embedded in the kin networks of Indian women. Indian women processed the furs, which allowed them to exert pressure on the exchange process, transforming the fur trade into the cloth trade. Women’s access to trade goods enhanced their authority, and their access to cloth led to a flowering of Indian clothing styles, situating them at the heart of a highly prosperous fur trade.
Threads, Traces, and the Affective Foundation of a Region: The Case Study of the Slate Falls First Nation (Canada)
Authors: Oliveira Frederico 
Published: July 2018

AbstractFor many generations, the seasonal mobility pattern over the territory has been an important factor defining family relations and land-use systems for the northern Anishinabeg in Canada. Using the case study of Slate Falls First Nation, this article, going beyond ecologically and economic-driven explanatory models, integrates history and indigenous perceptions of the environment as powerful instruments to record the people’s knowledge of the land and to assert self-determination. The emphasis is placed on people’s daily itineraries and cyclical practices with their ancestral territory, by using their year-round activities as the guiding temporal framework to connect their current lives with the old process of creating and maintaining a region that became their homeland.
Inhibition of SHIP2 activity inhibits cell migration and could prevent metastasis in breast cancer cells
Authors: Ghosh Somadri , Scozzaro Samuel , Ramos Ana Raquel , Delcambre Sébastien , Chevalier Clément , Krejci Pavel , Erneux Christophe 
Published: July 2018

ABSTRACT
Metastasis of breast cancer cells to distant organs is responsible for ∼50% of breast cancer-related deaths in women worldwide. SHIP2 (also known as INPPL1) is a phosphoinositide 5-phosphatase for phosphatidylinositol (3,4,5)-trisphosphate [PI(3,4,5)P3] and phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2]. Here we show, through depletion of SHIP2 in triple negative MDA-MB-231 cells and the use of SHIP2 inhibitors, that cell migration appears to be positively controlled by SHIP2. The effect of SHIP2 on migration, as observed in MDA-MB-231 cells, appears to be mediated by PI(3,4)P2. Adhesion on fibronectin is always increased in SHIP2-depleted cells. Apoptosis measured in MDA-MB-231 cells is also increased in SHIP2-depleted cells as compared to control cells. In xenograft mice, SHIP2-depleted MDA-MB-231 cells form significantly smaller tumors than those formed by control cells and less metastasis is detected in lung sections. Our data reveal a general role for SHIP2 in the control of cell migration in breast cancer cells and a second messenger role for PI(3,4)P2 in the migration mechanism. In MDA-MB-231 cells, SHIP2 has a function in apoptosis in cells incubated in vitro and in mouse tumor-derived cells, which could account for its role on tumor growth determined in vivo.
High resolution isotropic diffusion imaging in post-mortem neonates: a feasibility study
Authors: McDowell Amy R , Shelmerdine Susan C , Carmichael David W , Arthurs Owen J 
Published: July 2018

Objective:
To investigate the potential of advanced diffusion weighted imaging (DWI) in post-mortem MRI (PMMR) at 3T.

Methods:
We acquired PMMR brain and body imaging in 12 neonates, mean gestational age 33.4 weeks (range 29–37 weeks) at 3T and 1.5T. Head and body diffusion imaging at 1.5T consisted of bipolar diffusion encoding and single-shot spin-echo echo-planar imaging (SE-EPI) for acquisition (echo time (TE) 96 ms; repetition time (TR) 2700 ms; voxel size 1.8 x 1.8 mm in-plane with slice thickness 5 mm; b-values of 500 and 1000 s/mm2 applied in three orthogonal directions; total acquisition time 2:12). A whole-body 3T diffusion imaging protocol using monopolar diffusion encoding and simultaneous multislice EPI acquisition with gradients applied in 12 uniformly distributed directions was obtained (TE 53.4 ms; TR 5600 ms; 1.8 mm isotropic; multiband factor 2; b-values of 250, 750, 1250 and 1750 s/mm2; acquisition time 2:09 for a single b-value).

Results:
There was significant improvement in image quality in multiband, multislice diffusion PMMR protocol. On visual assessment of image quality, 1.5T DWI scored poorly (mean 2.4 SD ± 0.47), and all 3T b-values individually scored significantly higher (p &lt; 0.001) apart from b = 250 s/mm2 which was not significantly different.

Conclusion:
Recent advances in diffusion sequences and hardware utilising higher field strengths and gradient performance allows whole-body diffusion PMMR imaging at high resolution with improved image quality compared to the current clinical approach.

Advances in knowledge:
We have demonstrated feasibility of a multislice, multiband quantitative diffusion imaging sequence in the perinatal post-mortem setting. This will allow more detailed and quantitative clinical PMMR investigations using diffusion MRI in the future.
POTENTIAL THERAPEUTIC EFFECT OF ZIKA VIRUS IN GLIOBLASTOMA TREATMENT
Authors: Nascimento Sâmia Israele Braz do , Santos Sheezara Teles Lira dos , Alves Bárbara Torquato , Aguilera Kevellyn Cruz , Menezes Airton César Pinheiro de , Alencar Ana Maria Correia , Andrade Ana Maria Lima Carneiro de , Leite Daniel Gonçalves , Melo Antonio Marlos Duarte de 
Published: July 2018

Since the twentieth century, humanity has been experiencing a public health reality marked by numerous mosquito-borne diseases (belonging to the arthropod class), known as arboviruses. The Zika virus has become in recent years a risk to Brazilian and international public health due to its devastating effect due to its pathogenesis but also to fetal neurological development, causing serious health problems such as microcephaly and Guillain-Barré Syndrome, but also myelitis and meningoencephalitis. However, scientists studying the Zika virus have been trying to use the agent's ability to cause infections in healthy cells to attack and destroy cancer cells, such as the case of grade IV astrocytoma known as Gliobastoma Multiforme (GBM), which is a tumor of the very aggressive central nervous system and worse prognosis among primary cancers. As a result of effective therapy for GBM and the tropism of this etiological agent for brain cells, the hypothesis is that this virus would cause cell death in glioblastomas through metabolic alterations induced by the induced viral infection, but further studies must be carried out to demonstrate this therapeutic advantage in using the virus for the treatment of this malignant disease. Keywords: Zika virus; Gliobastoma Multiforme; Tumor of the Central Nervous System.
THE INNOVATIONS, ADVANCES AND OUTLOOKS OF LIQUID BIOPSY IN ONCOLOGY: A LITERATURE REVIEW
Authors: Melo Antonio Marlos Duarte de , Silva Filho Messias Silvano Da , Alves Bárbara Torquato , Aguilera Kevellyn Cruz , Alencar Ana Maria Correia , Andrade Ana Maria Lima Carneiro de , Leite Daniel Gonçalves , Quidute Ricardo Souto 
Published: July 2018

Studies on the biology of cancer are multiplying and have been giving significant repercussions on the care of cancer patients, and there is a growing need to evaluate the biology of the tumor. Conventional tissue biopsies currently represent the gold standard in the diagnosis of cancer, but they are not suitable for serial analysis because of the need for invasive procedures, besides being able to present a high risk of life and also impossibility of reaching surgical in some tumors. To solve this obstacle, the use of the Liquid Biopsy, which analyzes the presence of biomarkers released by cancer cells, such as circulating tumor cells (CTCs), tumor cell DNA (ctDNA) and exosomes is being discussed. These techniques are non-invasive or minimally invasive and collect their samples from peripheral blood, plasma and serum, urine, saliva and cerebrospinal fluid (CSF). As they are already being used in the treatment of several histopathological types of cancer, these new techniques generally represent a revolution in the understanding of early diagnosis, choice of personalized treatment, follow-up of the treatment response in real time, detection of minimal residual disease and prognosis for malignant neoplasms. The objective of this study was to present a literature review to clarify the fundamental molecular and clinical aspects involved in this revolutionary diagnostic technique by extracting the data from the sample. Keywords: Liquid Biopsy. Oncology.: literature review
Modern Dilbilime Göre Nahiv Terimlerinin Delaleti
Authors: ELSHAHHAT ABDELHAMİT SHOEİR Mohamed Rızk 
Published: July 2018

“Mustalah” (terim) kelimesi, “anlaşmak, uzlaşmak” anlamına gelmektedir. Zira “mustalah” (terim), bir ilmî disiplin mensuplarının, belirli bir bilimsel kavramı ifade etmek için kullandıkları kelime üzerindeki uzlaşımına delalet eder. Terimler, el-Hârizmî’nin ifadesiyle, bilimlerin anahtarlarıdır. Bunun yanı sıra “Terimleri anlamak, ilmin yarısıdır.” denilmiştir. Çünkü terim, bir kavrama delalet eden lafızdır; bilgi de, birbiriyle sistematik şekilde irtibatlı kavramlardan oluşmaktadır. Terimbilim ile dilbilim arasında sıkı bir bağ vardır: Terimbilim, uygulamalı dilbilimin kapsamına girmekte olup ikisi arasındaki ilişki âmm-hâss ilişkisidir. Terimbilim, kavramların net bir şekilde tanımlanmasından sonra başlar. Terimbilim, kelime üzerine araştırma yapmak ile sınırlı olup kavramlara delalet eden terimlere –ki terimler de bu kavramları ifade etmeye yarar- ağırlık verir. Dilbilim ise, kelimelerin yanı sıra cümle yapısı, ses gibi birçok farklı alanı inceler.Terimbilim, terimlerin belirli alanlarda sunumunu gerektirir. Ayrıca bir alanın terimleri, fikrî bir temele göre birbiri ardına gelir/art arda gelir. Bu yönüyle terimbilim, anlam sahalarına göre kelimelerin sunulması temeline dayalı sözlükçülük yaklaşımlarıyla ortaklık gösterir. Arap mirasında, kelimelerin konularına göre sınıflandırılması fikrine yönelik çok sayıda uygulama bulunmaktadır. Sözlük yazımının bu türünün en meşhur örneği İbn Sîde’nin “el-Muhassas” adlı sözlüğüdür. Dilbilim de –en azından- aynı dilde birçok dilbilim terimleri sözlüğünün olduğu bir ortamda terimlerin ortak olması/standartlaşması açısından terimbilime ihtiyaç duyduğu gibi dilbilim temellerinin oturduğu teknik ve dilsel esasları açıklamak için terimbilimin verilerine ihtiyaç duyar. Makale PlanıNahiv terimleri, eski ya da yeni dilbilim çalışmalarında büyük bir yekün teşkil etmektedir. Bundan dolayı, nahiv terimleri için –asgari olarak temel noktaları karşılayacak şekilde- özel bir sözlüğe ihtiyaç vardır. Ancak çalışmamız, en meşhur ve en yaygın terimlerle sınırlı olup bir giriş ve üç bölümden oluşmaktadır. Her bölüm, aşağıda olduğu üzere bazı terimleri kapsamaktadır. Birinci Bölüm: Cümle yapısı ve cümlenin anlamına dair terimler: Dil, olay, sözdizim düzeyi, nazm, nahvî delalet, fonksiyonel delalet, irab, mana ve nahvî zaman terimleri ele alınmaktadır. İkinci Bölüm: Dilbilgisi kuralları ve anlam ile olan ilişkisine dair terimler: Nahiv, gramatikal sistem, cümle, kelime grubu (et-terkib en-nahvî), âmil, nesh ve mefuller terimleri ele alınmaktadır. Üçüncü Bölüm: Nahiv ve anlam açısından “isnad” terimi: İsnad, müsned, müsned ileyh, umde ve fadle terimleri ele alınmaktadır.