bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Non Surgical Periodontal Therapy on the Serum C Reactive Protein Levels in Generalized Chronic Periodontitis Patients: A Clinical Study
Authors: Manocha Anish , DK Suresh , Gupta Shikha , Yakhmi Sharuti , Pandit Aashish 
Published: October 2018

Abstract
Background: Although many studies have compared circulating IL-6 and CRP concentrations in periodontal patients and controls, a limited number of studies have compared systemic inflammatory markers at baseline and follow-up and also Data on whether periodontal therapy affects serum CRP levels are inconclusive. Aims and Objective: By the virtue of this study, an attempt was made to evaluate and compare the effect of non surgical periodontal therapy on serum C-Reactive Protein levels in Generalized chronic periodontitis patients. Material and Method: A total of thirty patients with Generalised chronic periodontitis, within the age range of 30-70 years, were selected and underwent non surgical periodontal therapy. Further, they were put on a two month follow up after post operative phase for evaluation and comparison of pre and post values. Results and Conclusion: The results of our study showed that non surgical periodontal therapy significantly reduces the serum levels of C-reactive protein along with other clinical parameters in patients with generalised chronic periodontitis.
Varones 46, XX: a propósito de dos casos genéticamente distintos
Authors: Paneque Arianne , Armendáriz Stefany , Reyes Silva Carlos , Garzón Castro Maribel , Tambaco Jijón Nina 
Published: October 2018

Introducción Los desórdenes de diferenciación sexual son condiciones clínicas en las que existe una discrepancia entre el sexo cromosómico y el sexo fenotípico de un individuo. Esas condiciones suelen resultar angustiantes para los pacientes y sus familias e incluso para el equipo médico tratante debido a la dificultad en diagnosticarlas.
Objetivo Presentar las características clínicas, genéticas y hormonales de dos varones con desórdenes de diferenciación sexual.
Método Se realizó un estudio descriptivo basado en la revisión y análisis de datos de la historia clínica y la confrontación de los resultados con reportes similares.
Resultados Se observaron dos individuos con fenotipo masculino y diagnóstico de hipogonadismo hipergonadotrófico con cariotipo 46, XX. El primer caso presentó testes pequeños y azoospermia, mientras que el segundo caso presentó baja talla, criptorquidea bilateral congénita y escrotos hipoplásicos. En ambos pacientes se exploró la presencia del gen SRY, confirmando su presencia en el primer caso y ausencia en el segundo caso.
Conclusiones El diagnóstico genético-molecular actual apela a la combinación de técnicas tradicionales junto a técnicas modernas, como secuenciación por paneles genéticos a fin de identificar etiológicamente los desórdenes de diferenciación sexual. La presentación de esos casos aún se considera rara debido a su baja tasa de frecuencia poblacional, por lo que su reporte siempre resultará útil a la comunidad científica ya que muestran las distintas formas de presentación clínica y el manejo multidisciplinario de esos casos en diferentes contextos clínicos.
Differenzialdiagnose des Morbus Wilson
Authors: Tinta C. , Hermann W. 
Published: October 2018

ZusammenfassungNach dem Stellen der Verdachtsdiagnose Morbus Wilson gilt es, diese zu bestätigen. Bis zum eindeutigen Nachweis bzw. bei Ausschluss einer autosomal-rezessiven Störung des hepatischen Kupfertransporters ATP 7B sind Differenzialdiagnosen anhand der vorliegenden Befunde zu prüfen. Laborchemische Parameter des Kupferstoffwechsels weisen außer auf nicht relevante Normabweichungen auch auf andere Störungen im Kupferstoffwechsel hin.Neben bekannten Erkrankungen wie den Morbus Menkes, das Occipital Horn Syndrom (OHS), die Indian childhood cirrhosis (ICC) und den Coeruloplasminmangel werden neu entdeckte Störungen berücksichtigt. Dazu gehören das MEDNIK-Syndrom, das Huppke-Brendel-Syndrom und der Chaperonmangel CCS. Einen weiteren Schwerpunkt stellen alterskorrelierte Differenzialdiagnosen des kindlichen Ikterus und der Anämie sowie extrapyramidalmotorischer Bewegungsstörun-gen dar. Der Kayser-Fleischer-Kornealring wird als klassische ophthalmologische Manifestation relativiert. Mit der neu beschriebenen Manganspeichererkrankung besteht eine weitere seltene Metallstoffwechselstörung, die eine dem Morbus Wilson ähnliche Symptomatik hat.Wie diese Übersicht zeigt, ordnet sich der Morbus Wilson in ein weites Spektrum internistischer und neurologischer Krankheitsbilder mit Ikterus, Anämie und EPS ein. Auch neu entdeckte Krankheitsbilder des Mangan- und Kupferstoffwechsels sind relevant.
A bibliometric analysis of the interdisciplinary field of cultural evolution
Authors: Youngblood Mason , Lahti David 
Published: October 2018

AbstractThe science of cultural evolution is unified in its application of evolutionary logic to socially transmitted behavior, but diverse in methodologies and assumptions. Qualitative reviews have encouraged integration by illuminating points of divergence and fostering interaction. This effort would be greatly enhanced by quantitative data on patterns of collaboration and idea sharing in the literature. In the present study, we apply a novel combination of network, cluster, and bibliometric analyses to an extensive dataset of publications on cultural evolution, in order to represent the structure of the field and evaluate the level of disciplinary integration. We first construct a co-authorship network and identify subdisciplines. We then use bibliometric analyses to describe each subdiscipline and investigate trends in collaboration and productivity. Lastly, we assess the topographical distance and degree of citation sharing between subdisciplines, as well as the diversity of subject categories within subdisciplines. Our results reveal an increase in productivity and collaboration over time, albeit a higher inequality in author productivity than expected. Our structural approach reveals research subcommunities with differential levels of integration, citation sharing, and subject diversity. These findings confirm the emergence of a vigorous interdisciplinary field, and indicate ways to foster integration and synthesis in cultural evolution.
Changes in resource partitioning between and within organs support growth adjustment to neighbor proximity in
Brassicaceae
seedlings
Authors: de Wit Mieke , George Gavin M. , Ince Yetkin Çaka , Dankwa-Egli Barbara , Hersch Micha , Zeeman Samuel C. , Fankhauser Christian 
Published: October 2018

Significance
In dense communities, plants compete for light and sense potentially threatening neighbors prior to actual shading. In response to neighbor proximity cues, shade-intolerant plants selectively elongate stem-like structures, thereby enhancing access to unfiltered sunlight. Although key steps in plant proximity sensing and signaling have been identified, we know little about the metabolic adaptations underlying enhanced stem growth. Here, we show that, following the detection of neighbor proximity cues, seedlings allocate more carbon fixed in the cotyledons to the faster elongating hypocotyl. Moreover, we show that sucrose transport and a transcription factor responding to light and metabolic cues control hypocotyl elongation. Collectively, our work provides important insights into the metabolic changes underlying organ-specific growth adaptations to an environmental stress signal.
The Qur’an translatability
Authors: Al-Abdullatif Mohammed 
Published: October 2018

AbstractThe Qur’an is the uncontested central religious text of Islam. Many Muslim scholars dogmatically believe that the language of the Qur’an is the miraculous word of God revealed directly to his Prophet, and disagree that it is possible to translate it into any other language. On the other hand, some scholars, old and new, have argued for the permissibility of its translations for linguistic and pragmatic reasons. The polemics surrounding the translatability of The Qur’an bring to light other enduring debates on the permissibility of translating the word of God into an earthly language even if it has been revealed in one, and if one can safely describe this as a translation.The debate on the translatability of the Qur’an constitutes one of the most controversial issues in Arabic-to-other-languages translation. This paper aims at weighing, as objectively as possible, the justifications variously employed by each camp to rationalize its position. It also touches upon some of the philosophical issues of translatability itself, along with a critical discussion on the traditional Arabic linguists’ views of meaning and translation.The paper assumes that some readers, particularly non-Muslim readers, are not fully familiar with certain rhetorical and linguistic issues that might be familiar to Muslim scholars. For reasons of clarity, the paper accordingly includes some detailed discussions of certain essential issues.
Association between residual feed intake and enteric methane emissions in Hereford steers
Authors: Dini Yoana , Cajarville Cecilia , Gere José I , Fernandez Sofía , Fraga Martín , Pravia Maria Isabel , Navajas Elly Ana , Ciganda Verónica S 
Published: October 2018

Abstract
The objective of this study was to quantify the emissions of enteric CH4 from growing Hereford steers raised under feedlot conditions based on contrasting levels of residual feed intake (RFI). A repeated measurements experiment was conducted over 20 d to determine CH4 production from two groups of nine Hereford steers, with contrasting RFI values (mean ± SD): low RFI (LRFI group; −0.78 ± 0.22 kg DMI/d) vs. high RFI (HRFI group; 0.83 ± 0.34 kg DMI/d). Steers were selected from a larger contemporary population in which the RFI was evaluated. Steers were maintained under confined conditions with ad libitum access to water and feed, comprising a total mixed ration of 55% sorghum silage, 21% barley silage, 21% corn grain, and 3% protein–mineral–vitamin–premix, provided twice a day. Before the beginning of CH4 measurements, the live weight of both groups of animals was determined, which on average (±SEM) was 357.0 ± 5.11 and 334.0 ± 10.17 kg in the LRFI and HRFI groups, respectively. Methane emission (g/d) was measured on each animal with the sulfur hexafluoride (SF6) tracer technique, during two consecutive periods of 5 d. Individual daily intake and feeding behavior characteristics were measured using a GrowSafe automated feeding system (Model 6000, GrowSafe Systems Ltd, Airdrie, Alberta, Canada). Methanogens in the ruminal content were quantified using quantitative polymerase chain reaction with primers targeting the mcrA gene. Methane emission was near 27% lower in animals with LRFI when expressed in absolute terms (g/d; 26.8%; P = 0.009), by unit of dry matter intake (g CH4/kg; 27.9%, P = 0.021), or as % of gross energy intake (26.7%; P = 0.027). These differences could not be explained by differences in amount of total of methanogens (average = 9.82 log10 units; P = 0.857). However, there were some differences in animal feeding behavior that could explain these differences (e.g., LRFI animals tended to spend less time in feeders). Our results suggest that, in Hereford steers, the selection by RFI values is a promising mitigation strategy for the reduction of the emission of enteric CH4.
Biogeodynamics: bridging the gap between surface and deep Earth processes
Authors: Zerkle Aubrey L. 
Published: October 2018

Life is sustained by a critical and not insubstantial set of elements, nearly all of which are contained within large rock reservoirs and cycled between Earth's surface and the mantle via subduction zone plate tectonics. Over geologic time scales, plate tectonics plays a critical role in recycling subducted bioactive elements lost to the mantle back to the ocean–biosphere system, via outgassing and volcanism. Biology additionally relies on tectonic processes to supply rock-bound ‘nutrients’ to marine and terrestrial ecosystems via uplift and erosion. Thus, the development of modern-style plate tectonics and the generation of stable continents were key events in the evolution of the biosphere on Earth, and similar tectonic processes could be crucial for the development of habitability on exoplanets. Despite this vital ‘biogeodynamic’ connection, directly testing hypotheses about feedbacks between the deep Earth and the biosphere remains challenging. Here, I discuss potential avenues to bridge the biosphere–geosphere gap, focusing specifically on the global cycling and bioavailability of major nutrients (nitrogen and phosphorus) over geologic time scales.This article is part of a discussion meeting issue ‘Earth dynamics and the development of plate tectonics’.
Cryopreservation and transplantation of common carp spermatogonia
Authors: Franěk Roman , Marinović Zoran , Lujić Jelena , Urbányi Béla , Fučíková Michaela , Kašpar Vojtěch , Pšenička Martin , Horváth Ákos 
Published: October 2018

AbstractCommon carp (Cyprinus carpio) is one of the most cultured fish species over the world with many different breeds and plenty of published protocols for sperm cryopreservation, however, data regarding preservation of gonadal tissue and surrogate production is still missing. A protocol for freezing common carp spermatogonia was developed through varying different factors along a set of serial subsequent experiments. Among the six cryoprotectants tested, the best survival was achieved with dimethyl sulfoxide (Me2SO). In the next experiment, a wide range of cooling rates (0.5–10 °C/min) and different concentrations of Me2SO were tested resulting in the highest survival using 2 M Me2SO and cooling rate of –1 Q59 A When testing different tissue sizes and incubation times in the cryomedium, the highest viability was observed when incubating 100 mg tissue fragments for 30 min. Finally, sugar supplementation did not yield significant differences. When testing different equilibration (ES) and vitrification solutions (VS) used for needle-immersed vitrification, no significant differences were observed between the tested groups. Additionally, varied exposure time to VS did not improve the vitrification outcome where the viability was 4-fold lower than that of freezing. The functionality of cryopreserved cells was tested by interspecific transplantation into sterilized goldfish recipients. The exogenous origin of the gonads in goldfish recipients was confirmed by molecular markers and incorporation rate was over 40% in both groups at 3 months post transplantation. Results of this study can serve as an alternative way for long-term preservation of germplasm in carp which can be recovered in a surrogate recipient.
MdMYB3 helps regulate anthocyanin accumulation in apple calli under moderately acidic conditions
Authors: Wang Yi-Cheng , Sun Jing-Jing , Qiu Yan-Fen , Gong Xiao-Jun , Ma Li , Zhang Zong-Ying , Feng Shou-Qian , Wang Yan-Ling , Chen Xue-Sen 
Published: October 2018

AbstractAnthocyanins are the key factors controlling the coloration of plant tissues. However, the molecular mechanism underlying the effects of environmental pH on the synthesis of apple anthocyanins is unclear. In this study, we analyzed the anthocyanin contents of apple calli cultured in media at different pHs (5.5, 6.0, and 6.5). The highest anthocyanin content was observed at pH 6.0. Additionally, the moderately acidic conditions up-regulated the expression of MdMYB3 as well as specific anthocyanin biosynthesis structural genes (MdDFR and MdUFGT). Moreover, the anthocyanin content was higher in calli overexpressing MdMYB3 than in the wild-type controls at different pHs. Yeast one-hybrid assay results indicated that MdMYB3 binds to the MdDFR and MdUFGT promoters in vivo. An analysis of the MdDFR and MdUFGT promoters revealed multiple MYB-binding sites. Meanwhile, electrophoretic mobility shift assays confirmed that MdMYB3 binds to the MdDFR and MdUFGT promoters in vitro. Furthermore, GUS promoter activity assays suggested that the MdDFR and MdUFGT promoter activities are enhanced by acidic conditions, and the binding of MdMYB3 may further enhance activity. These results implied that an acid-induced apple MYB transcription factor (MdMYB3) promotes anthocyanin accumulation by up-regulating the expression of MdDFR and MdUFGT under moderately acidic conditions.
The effect of facial expression on contrast sensitivity: a behavioural investigation and extension of Hedger, Garner, & Adams (2015)
Authors: Webb Abigail L. M. , Hibbard Paul B. 
Published: October 2018

AbstractIt has been argued that rapid visual processing for fearful face expressions is driven by the fact that effective contrast is higher in these faces compared to other expressions, when the contrast sensitivity function is taken into account (Hedger, Garner, & Adams, 2015). This proposal has been upheld by data from image analyses, but is yet to be tested at the behavioural level. The present study conducts a traditional contrast sensitivity task for face images of various facial expressions. Findings show that visual contrast thresholds do not differ for different facial expressions We re-conduct analysis of faces’ effective contrast, using the procedure developed by Hedger, Garner, & Adams (2015), and show that higher effective contrast in fearful face expressions relies on face images first being normalised for RMS contrast. When not normalised for RMS contrast, effective contrast in fear expressions is no different, or sometimes even lower, compared to other expressions. These findings are discussed in relation to the implications of contrast normalisation on the salience of face expressions in behavioural and neurophysiological experiments, and also the extent that natural physical differences between facial stimuli are masked during stimulus standardisation and normalisation.
Minimal medical imaging can accurately reconstruct geometric bone models for musculoskeletal models
Authors: Suwarganda Edin K. , Diamond Laura E. , Saxby David J. , Lloyd David G. , Bryce A. Killen , Savage Trevor N. 
Published: October 2018

AbstractAccurate representation of subject-specific bone anatomy in lower-limb musculoskeletal models is important for human movement analyses and simulations. Mathematical methods can reconstruct geometric bone models using incomplete imaging of bone by morphing bone model templates, but the validity of these methods has not been fully explored. The purpose of this study was to determine the minimal imaging requirements for accurate reconstruction of geometric bone models. Complete geometric pelvis and femur models of 14 healthy adults were reconstructed from magnetic resonance imaging through segmentation. From each complete bone segmentation, three sets of incomplete segmentations (set 1 being the most incomplete) were created to test the effect of imaging incompleteness on reconstruction accuracy. Geometric bone models were reconstructed from complete sets, three incomplete sets, and two motion capture-based methods. Reconstructions from (in)complete sets were generated using statistical shape modelling, followed by host-mesh and local-mesh fitting through the Musculoskeletal Atlas Project Client. Reconstructions from motion capture-based methods used positional data from skin surface markers placed atop anatomic landmarks and estimated joint centre locations as target points for statistical shape modelling and linear scaling. Accuracy was evaluated with distance error (mm) and overlapping volume similarity (%) between complete bone segmentation and reconstructed bone models, and statistically compared using a repeated measure analysis of variance (p<0.05). Motion capture-based methods produced significantly higher distance error than reconstructions from (in)complete sets. Pelvis volume similarity reduced significantly with the level of incompleteness: complete set (92.70±1.92%), set 3 (85.41±1.99%), set 2 (81.22±3.03%), set 1 (62.30±6.17%), motion capture-based statistical shape modelling (41.18±9.54%), and motion capture-based linear scaling (26.80±7.19%). A similar trend was observed for femur volume similarity. Results indicate that imaging two relevant bone regions produces overlapping volume similarity > 80% compared to complete segmented bone models. These findings have implications for improving movement analysis and simulation with subject-specific musculoskeletal models.
Dynamic Functional Network Connectivity In Schizophrenia With MEG And fMRI, Do Different Time Scales Tell A Different Story?
Authors: Sanfratello Lori , Houck Jon , Calhoun Vince 
Published: October 2018

AbstractThe importance of how brain networks function together to create brain states has become increasingly recognized. Therefore, an investigation of eyes-open resting state dynamic functional network connectivity (dFNC) of healthy controls (HC) versus that of schizophrenia patients (SP) via both fMRI and a novel MEG pipeline was completed. The fMRI analysis used a spatial independent component analysis (ICA) to determine the networks on which the dFNC was based. The MEG analysis utilized a source-space activity estimate (MNE/dSPM) whose result was the input to a spatial ICA, on which the networks of the MEG dFNC was based. We found that dFNC measures reveal significant differences between HC and SP, which depended upon the imaging modality. Consistent with previous findings, a dFNC analysis predicated on fMRI data revealed HC and SP remain in different overall brain states (defined by a k-means clustering of network correlations) for significantly different periods of time, with SP spending less time in a highly-connected state. The MEG dFNC, in contrast, revealed group differences in more global statistics: SP changed between meta-states (k-means cluster states that are allowed to overlap in time) significantly more often and to states which were more different, relative to HC. MEG dFNC also revealed a highly connected state where a significant difference was observed in inter-individual variability, with greater variability among SP. Overall, our results show that fMRI and MEG reveal between-group functional connectivity differences in distinct ways, highlighting the utility of using each of the modalities individually, or potentially a combination of modalities, to better inform our understanding of disorders such as schizophrenia.
m-commerce technology adoption
Authors: Chhonker Mayanka Singh , Verma Deepak , Kar Arpan Kumar , Grover Purva 
Published: October 2018

Purpose
The purpose of this study is to consolidate the state of research in mobile commerce (m-commerce) technology adoption from 2008 to 2017. This study not only reviews the evolution of m-commerce literature but also highlights the significant contribution of authors and their productive collaborations in the development of this area.

Design/methodology/approach
A total of 184 peer-reviewed articles focusing on m-commerce adoption were obtained after applying search criteria on Scopus database. After using inclusion and exclusion criteria to achieve the objective of this study, 86 journals were shortlisted. The study further discusses the dispersion of various m-commerce applications being explored in m-commerce literature. In addition, dominating technology adoption theories and the most used keywords have also been identified and discussed in this study.

Findings
This study indicates that technology acceptance model and unified theory of acceptance and use of technology are the most exploited technology adoption theories. Moreover, the dominating constructs in literature are perceived usefulness, ease of use social influence/social norm on behavior intention, attitude intention followed by performance expectancy, facilitating condition and effort expectancy influence on intention.

Originality/value
This study presents a detailed association rule mining and community analysis to show the association among constructs such as usefulness, ease of ease, social influence and intention as dominant group in this area. The study also identifies lesser explored constructs and indicates possible future research to validate and strengthen their understanding further.