bluuebunny/crossref_metadata_2025_split huggingface dataset:
Möglichkeiten und Management gefäßrekonstruktiver Eingriffe im Rahmen viszeralchirurgischer Operationen und ihrer perioperativen Betreuung – eine selektive Auswahl repräsentativer Fallkonstellationen
Authors: Barth Udo , May Jens Peter , Albrecht Roland , Pech Maciej , Halloul Zuhir , Meyer Frank 
Published: July 2019

Zusammenfassung
Einleitung Das Ineinandergreifen der chirurgischen Fachdisziplinen bei der Bewältigung komplexer, chirurgisch therapierbarer Erkrankungen ist eine eminente Voraussetzung, um die Erfolgschancen der Behandlung zu steigern. Bei der zunehmenden Erweiterung der Indikationsgrenzen zur operativen Behandlung von ausgedehnten multiviszeralen Tumoren, bei iatrogenen Gefäßverletzungen im viszeral- und onkologisch-chirurgischen Operationsfeld und der mesenterialen Ischämie ist eine gefäßchirurgische Expertise vonnöten.
Zielsetzung Narrative Übersicht auf Basis aktueller wissenschaftlicher Referenzen und eigener klinischer und operativer Erfahrungen im entscheidungstechnischen Herangehen zum taktischen Vorgehen und zu gefäßrekonstruktiven Möglichkeiten bei viszeralchirurgischen Eingriffen.
Ergebnisse Beim Pankreaskarzinom mit seiner anhaltend schlechten Prognose ist die R0-Resektion die einzig kurative Therapieoption – damit werden intraoperativ erweiterte Anforderungen an den Chirurgen gestellt. Während die arterielle Gefäßrekonstruktion aufgrund erhöhter Morbidität und limitierter Evidenz weiter in der Diskussion und spezifischen Fallkonstellationen vorbehalten bleibt, ist die venöse Rekonstruktion mittlerweile etabliert. Auch bei ausgedehnten retroperitonealen Sarkomen ist im Rahmen multiviszeraler Resektionen die Rekonstruktion der infiltrierten V. cava inferior oder A. iliaca communis durch eine Patchplastik oder autologen Bypass-/Segmentersatz notwendig. Im Rahmen von inflammatorischen Prozessen sowie Tumoradhäsionen/-infiltrationen zu angrenzenden anatomischen Strukturen können intraoperative Gefäßverletzungen oder postoperative Gefäßalterationen auftreten, deren Rekonstruktion durch anatomische Varianten erschwert wird. Die extrem hohe Anforderung an den Viszeralchirurgen bei mesenterialen Ischämien wird durch eine kompetente Beurteilung der mesenterialen Gefäßstrecke auf Basis einer adäquaten Bildgebung und durch den Zeitfaktor bestimmt. Ein promptes rekanalisierendes Vorgehen entscheidet mit über die Prognose des Krankheitsbildes.
Schlussfolgerung Gefäßrekonstruktionen in der Viszeralchirurgie, insbesondere der Tumorchirurgie, stellen hohe Anforderungen an die Expertise des Operateurs. Eminent dabei ist neben einer guten präoperativen Diagnostik eine entwickelte spezifisch gefäßchirurgisch-medizinische wie auch fachübergreifende Erfahrung in Fallmanagement und in der OP-Taktik/-Technik.
Laparoskopisches Ausschalten eines Aneurysmas der A. lienalis
Authors: Ellebrecht David Benjamin , Horn Marco , Pross Moritz , Keck Tobias , Kleemann Markus 
Published: July 2019

Zusammenfassung
Zielsetzung Viszeralarterienaneurysmata stellen seltene, jedoch gefürchtete Gefäßpathologien dar. Am häufigsten sind die Äste des Truncus coeliacus und in diesem Zusammenhang die A. lienalis betroffen. Meist werden Viszeralaneurysmata erst diagnostiziert, wenn eine Blutungskomplikation durch die Aneurysmaruptur auftritt. Folglich wird bei einer vorherigen Detektion eine frühzeitige Ausschaltung nach Diagnosestellung empfohlen. Als primäres Verfahren bietet sich hierbei die endovaskuläre Ausschaltung an. Falls eine endovaskuläre Ausschaltung nicht möglich ist, kann auch durch eine chirurgische Ausschaltung das Viszeralaneurysma erfolgreich therapiert werden.
Indikation Nachgewiesenes Milzarterienaneurysma im Hilusbereich. Ein endovaskuläres Coiling hätte voraussichtlich eine Ischämie der Milz bedingt.
Methode Laparoskopische Ausschaltung des Milzarterienaneurysmas.
Schlussfolgerung Bei für endovaskuläre Therapie nicht geeigneten Pathologien der A. lienalis stellt die laparoskopische Ausschaltung eine sicher und effektiv durchführbare minimalinvasive Option dar.
Klinische Wirksamkeit von „FlexiTeam“ (Home Treatment und intensivierte ambulante Behandlung) – Vergleich einer Behandlung in einem Modellprojekt nach § 64b in Berlin mit der stationären Behandlung
Authors: Weinmann Stefan , Wiedmann Simon , Breidert Tilo , Bohe Matthias , Pfeiffer Jan , Rosenberger Eva , Bechdolf Andreas 
Published: July 2019

Zusammenfassung
Ziel der Studie Verglichen wurde die klinische Wirksamkeit von „Home Treatment“ (HT) zusammen mit intensiver ambulanter Behandlung (IAB) im Modellprojekt „FlexiTeam“ (FT) mit einer stationär-psychiatrischen Routinebehandlung.
Methodik Im Rahmen einer kontrollierten gematchten Vorher-Nachher-Studie wurden Routinedaten von jeweils 83 Patienten im FT und in der stationär-psychiatrischen Routinebehandlung hinsichtlich (teil-)stationärer Wiederaufnahmerate und Verweildauer im 6- und 12-Monats-Follow-up verglichen.
Ergebnisse Es zeigt sich keine signifikante Reduktion der (teil-)stationären Verweildauer im Index-Aufenthalt. Durch die Behandlung im FT konnte eine signifikante Reduktion sowohl der (teil-)stationären Wiederaufnahmerate als auch der Verweildauer im 6- und 12-Monats-Follow-up erreicht werden.
Schlussfolgerung Eine flexible Kombination aus IAB und HT stellt eine wirksame Ergänzung zur stationär-psychiatrischen Routinebehandlung dar und kann bei geeigneten Patienten das Risiko stationärer Wiederaufnahmen senken.
Unicompartmental Knee Replacement Combined to Anterior Cruciate Ligament Reconstruction: Midterm Results
Authors: Ventura Alberto , Legnani Claudio , Terzaghi Clara , Macchi Vittorio , Borgo Enrico 
Published: July 2019

AbstractA study was conducted to retrospectively evaluate the outcomes of combined medial unicompartmental knee replacement (UKR) and anterior cruciate ligament (ACL) reconstruction. The hypothesis was that this procedure would lead to satisfying results in patients affected by medial osteoarthritis and ACL insufficiency. Fourteen patients with ACL deficiency and concomitant medial compartment symptomatic osteoarthritis were treated from 2006 to 2010. Twelve of them were followed-up for an average time of 7.8 year (range: 6–10 years). Assessment included Knee Osteoarthritis Outcome score (KOOS), Oxford Knee score (OKS), American Knee Society scores (AKSS), Western Ontario and McMaster (WOMAC) index of osteoarthritis, Tegner's activity level, objective examination including instrumented laxity test with KT-1000 arthrometer, and standard X-rays. KOOS score, OKS, WOMAC index, and the AKSS improved significantly at follow-up (p < 0.001). There was no clinical evidence of instability in any of the knees as evaluated with clinical and instrumented laxity testing (p < 0.001). No pathologic radiolucent lines were observed around the components. In one patient, a total knee prosthesis was implanted due to the progression of signs of osteoarthritis in the lateral compartment 3 years after primary surgery. UKR combined with ACL reconstruction is an effective therapeutic option for the treatment of combined medial unicompartmental knee osteoarthritis and ACL deficiency and confirms subjective and objective clinical improvement up to 8 years after surgery. This study reflects level IV evidence.
A new field test to estimate the aerobic and anaerobic thresholds and maximum parameters
Authors: Giovanelli Nicola , Scaini Stefano , Billat Veronique , Lazzer Stefano 
Published: July 2019

AbstractEvaluation of cardiorespiratory parameters is important in athletic population in order to monitor the training status and define training intensities. The aim of this study was to validate an easy‐to‐perform running test called RABIT® (Running Advisor Billat Training) for detecting aerobic (AerT) and anaerobic (AnT) threshold and maximum parameters. Fifteen trained runners completed a graded (GRAD) and RABIT test (four self‐selected pace steps: (i) 10 minutes at free warm‐up pace, (ii) 5 minutes at medium pace, (iii) 3 minutes at hard pace, (iv) 10 minutes at easy pace). We compared the cardiorespiratory parameters and running speed of the RABIT with those corresponding to AerT, AnT or maximum parameters obtained by the GRAD. The ⩒O2max, HRmax, RERmax and running speed max measured during the 3‐minute hard pace of the RABIT were not statistically different from the maximum parameters measured during GRAD (p > 0.05). The ⩒O2, HR and RER measured during the medium and easy pace of the RABIT were not significantly different from the AnT and AerT parameters measured during GRAD. In conclusion, RABIT was validated for all the maximum parameters and for most of Ant‐ and AerT‐related parameters and then it might be used for detecting training zones in athletes.
Acetylcholinesterase is not a generic marker of extracellular vesicles
Authors: Liao Zhaohao , Jaular Lorena Martin , Soueidi Estelle , Jouve Mabel , Muth Dillon C. , Schøyen Tine H. , Seale Tessa , Haughey Norman J. , Ostrowski Matias , Théry Clotilde , Witwer Kenneth W. 
Published: July 2019

ABSTRACTAcetylcholinesterase (AChE) activity is found in abundance in reticulocytes and neurons and was developed as a marker of reticulocyte EVs in the 1970s. Easily, quickly, and cheaply assayed, AChE activity has more recently been proposed as a generic marker for small extracellular vesicles (sEV) or exosomes, and as a negative marker of HIV‐1 virions. To evaluate these proposed uses of AChE activity, we examined data from different EV and virus isolation methods using T‐lymphocytic (H9, PM1 and Jurkat) and promonocytic (U937) cell lines grown in culture conditions that differed by serum content. When EVs were isolated by differential ultracentrifugation, no correlation between AChE activity and particle count was observed. AChE activity was detected in non‐conditioned medium when serum was added, and most of this activity resided in soluble fractions and could not be pelleted by centrifugation. The serum‐derived pelletable AChE protein was not completely eliminated from culture medium by overnight ultracentrifugation; however, a serum “extra‐depletion” protocol, in which a portion of the supernatant was left undisturbed during harvesting, achieved near‐complete depletion. In conditioned medium also, only small percentages of AChE activity could be pelleted together with particles. Furthermore, no consistent enrichment of AChE activity in sEV fractions was observed. Little if any AChE activity is produced by the cells we examined, and this activity was mainly present in non‐vesicular structures, as shown by electron microscopy. Size‐exclusion chromatography and iodixanol gradient separation showed that AChE activity overlaps only minimally with EV‐enriched fractions. AChE activity likely betrays exposure to blood products and not EV abundance, echoing the MISEV 2014 and 2018 guidelines and other publications. Additional experiments may be merited to validate these results for other cell types and biological fluids other than blood.
The effect of boron dopant on hydrogenated graphene for hydrogen storage application
Authors: Susilo D N A , Ganta M , Sunnardianto G K , Handayani M 
Published: July 2019

Abstract
We investigate the effect of boron dopant on the charge transfer and reaction pathways of hydrogenated graphene based upon density functional theory calculation. We focused on the particularly the charge transfer rate of trimer hydrogen adsorption and its reaction pathways. Firstly, we investigated the effect of B dopant on the pristine graphene which is revealed that B-C bond length prior to hydrogenation is around 1.49 Å resulting the deformed structure of graphene since the size of boron is a bit larger that carbon atom. We have also calculated the charge transfer (CTR) from hydrogen to carbon atom after boron subtitution, we found that there is an increasing the CTR with respect to the pristine graphene indicated that the strong bond length between hydrogen and carbon.
Effect of solution treatment on microstructure and corrosion behaviour of Mg-9Al-1Zn alloys
Authors: Naldi R , Anawati A 
Published: July 2019

Abstract
The effect of solution treatment on the microstructure and corrosion behavior of cast Mg-9Al-1Zn (AZ91) were studied by using electro-optical microscopy, X-ray diffraction (XRD) technique, and weight loss method. The solution treatment was done at 415°C for 2 h followed by a water quench. The as-cast AZ91 alloy composed of α-Mg phase and β-phase (Mg17Al12). Most of the β-phase was segregated along the grain boundaries. A significant reduction in the volume fraction of β-phase was obtained as a result of solution treatment. The β-phase precipitate was distributed randomly both at grain boundaries and in the grain interior as discrete particles of a few µm sizes. The solution treatment induced grain growth resulting in a significantly larger equiaxed grain in the range 100-500 µm. A higher corrosion rate was obtained for the solution treated alloy than the untreated one. The β-phase precipitate played a dual role in the corrosion of AZ91 alloy depending on its volume fraction in the alloy. A nearly continuous distribution of β-phase along grain boundaries in the as-cast alloy served as a barrier for corrosion across grain while the distribution of discrete particles in the solution-treated alloy accelerated corrosion in the surrounding matrix.
Relaxation behavior of natural rubber composites based on mooney stress relaxation and rheometer data
Authors: Indrajati I N , Setyorini I 
Published: July 2019

Abstract
Studies on relaxation behavior of natural rubber composites were conducted by Mooney stress relaxation coupled with rheometer data. The effect of filler (carbon black N-330) and sulphur loading was monitored on the relaxation behavior. Elasticity of the composites was also determined in term of elongation at break and hardness, as confirmation to the relaxation behavior. The experiments were conducted by varying the N-330 30, 35, 40 and 45 phr with the sulphur baseline of 2 phr. While sulphur loading was varying from 1, 2, 3 and 4 phr with the N-300 baseline of 30 phr. Mooney experiments were carried out at 100 ºC, while rheometer experiments were conducted in a moving die rheometer at 150ºC. Results finding showed that the relaxation rate was reduced with N-330 loading or sulphur loading due to restriction of rubber molecule chain mobility by crosslinking formation. N-330 provided higher effect on stress relaxation rate compared to sulphur. Elongation of the composites was found to decrease upon filler or sulphur loading, while hardness was inversely.
Effect of Punch Parameters on Springback for Mild Carbon Steel in A V-Shape Bending Process
Authors: Suyuti M A , Iswar M , Nur R 
Published: July 2019

Abstract
The springback is variably sensitive to materials and process parameters. Considering springback occurred in a formed part is significant for designing tools and dies. In this paper, experiments of a V-shape bending test were performed for investigating the springback effect. The punch parameters variation has been observed in ASTM A-36 mild carbon steel. Punch radius used and punch angle). The V-shape bending of mild steel was performed using Universal Testing Machine (UTM) at various punch radius (2, 4, and 6 mm) and punch angle (80°, 85°, and 90°) and at constant of die radius (10 mm) and die width (50 mm). The experimental result indicates that the punch radius has a most significant impact on springback behaviour of these sheet metal. This is verified through our experimental work using V-shape bend testing.
Erosion behaviour of alumina ceramic coating on mild steel by the modified composition of phosphate binder
Authors: Idamayanti D , Ginanjar D , Bandanadjaja B , Purwadi W , Lilansa N 
Published: July 2019

Abstract
The Pulverizer pipe made of mild steel had erosion failure due to coal dust impacting, thus its service life also reduces. The ceramic coating overlay on the surface of mild steel is one of the appropiate ways to protect the mild steel from erosion. This research is aimed to perform a ceramic coating over the surface of the mild steel using a dipping method to improve its erosion resistance by using the alumina-phosphate ceramic coating. The coating layer is formed by the reaction between monoaluminum phosphate (MAP) as a binder and Al2O3 particles. It transforms into berlinite phase when heated at an elevated temperature. The observation is carried out with the variation of the MAP binder composition Al:P 25:75, 28:72, 30:70 and the Al2O3/MAP slurry is given at 40/60. Scanning electron microscopy is used to characterize the coating morphology. X-ray diffraction is applied to investigate the ceramic coating phases. The gas erosion jet measures erosion resistance of the ceramic coating. From the test result, it can be concluded that the binder composition influenced the erosion behaviour of alumina ceramic coating, the binder with Al:P (30:70) showed the erosion resistance increasing four times compared to the condition without coating.
Optimization of ZnO-nanorods addition toward Li4Ti5O12 (LTO) performance using sol-gel solid state method as half-cell lithium-ion battery anode
Authors: Priyono B , Panjaitan A A S , Syahrial A Z , Faizah  , Subhan A 
Published: July 2019

Abstract
Performance optimization for the anode of lithium-ion batteries (LIBs) can be conducted by adding ZnO through sol-gel solid-state reaction. In this research, the Li4Ti5O12 (LTO) used was synthesized through the sol-gel solid-state process and added with ZnOnanorods obtained ZnO synthesis after LTO synthesis done. LTO-ZnO obtained was characterized to determine the main phase and chemical composition by XRD and SEM-EDS respectively. Electrochemical performance of LTO-ZnO was tested by EIS, CV, and CD. ZnOnanorods characterization with SEM-EDS results shows that the ZnO inside the LTO dispersed homogeneously. Characterization using XRD revealed that the ZnO successfully enter the LTO with the variation of the amount of 4, 7, and 10 wt% of ZnO. Electric conductivity test shows improvement at an optimum addition amount of ZnO at 4 wt%, although BET result shows at the optimum amount of surface area with 75.545 m2/g. Electrochemical performance result shows optimum performance in ZnO at 4 wt% for its ability to withstand EIS test at 20C compared to 7 wt% and 10 wt%. Also, the capacity of 4 wt% added is 110.2 mAh/g compared to 7 wt% with 109.1 mAh/g and 10 wt% with 96.7 mAh/g.
Fabrication, microstructure and corrosion study of porous Mg-Ca-Zn using CaCO3 pre-treatment with sodium trisilicate
Authors: Erryani A , Al-aziz I , Lestari F P , Kartika I 
Published: July 2019

Abstract
Magnesium-based alloys have the good potential as a biodegradable implant that can be degraded in biological tissue. In this research, the fabrication of porous implant materials based on Mg-Ca-Zn alloy develop by powder metallurgy. CaCO3 as a foaming agent which previously coated by using sodium trisilicate has been used to obtain open celullar pores. The alloy compositions used in this research are Mg-Ca-3Zn-5CaCO3 and Mg-Ca-3Zn-10CaCO3. Sintering process is carried out at temperature of 600, 650 and 700 °C with holding time of 5h. The alloy is characterized by using XRD (microstructure analysis), SEM (surface and pore analysis) and corrosion test of alloys (electrochemical analysis using tafel graph). The microstructures of the alloy show MgO and Mg2Ca phase SEM results show the pores in the alloy with the size approximately arround 194.843-266,938μm. The corrosion rate in alloys is obtained in the range of 0.4-3.2 mmpy. The morphology of the alloy surface after corrosion process shows the volcano type. The corrosion process occurs localized where the electrochemical reaction occurs, so as to form a distinctive structure with the shape of the circle and the hole in the middle.
Ductility improvement of high density polyethylene (HDPE)-modified bitumen through adding modified lignin
Authors: Septimorien E A , Friskila L M D , Natasya B , Chalid M 
Published: July 2019

Abstract
High Density Polyethylene (HDPE) is added to bitumen to improve the mechanical properties as Polymer Modified Bitumen (PMB), but both of them have different chemical properties. To achieve best mechanical properties of the mixture coupling agent is needed such as lignin that has bipolar characteristic. In the previous research, unmodified lignin tendency of polarity is bigger thus modified with polyurethanee PEG to increase its non-polar parts. In order to confirm the potential of modified lignin as a coupling agent for HDPE-Modified Bitumen. Several stages of this experiment consists of sample preparation, characterization of raw materials, mixing, and characterization of the PE-Modified Bitumen. This experiment used hot melt mixing to mix modified lignin, HDPE, and bitumen. The result of this experimental was analysed by using Ductility test, FTIR and FESEM. The addition of modified lignin to HDPE-Modified Bitumen increase distribution and dispersion of HDPE particulates inside bitumen matrix, increasing PMB HDPE mechanical properties. Furthermore, FESEM characterization indicated that the addition of modified lignin gave better mixing of PE-Bitumen. FTIR showed an increase of intensities at non-polar peaks, and down at polar peaks compared with unmodified lignin. Ductility test showed that modified lignin has better compatibility as coupling agent than unmodified lignin. From this experiment, modified lignin can improve mixing between HDPE and Bitumen better than modified lignin. So, we can use modified lignin as the new coupling agent.
The Influence of Sn addition on the microstructure and mechanical properties of the new β-type Ti-Mo-Nb based alloys for implant material
Authors: Sutowo C , Senopati G , Supriadi S , Pramono A W , Suharno B 
Published: July 2019

Abstract
Titanium alloys are very interesting for biomedical applications due to excellent biocompatibility, corrosion resistance, lower density, and lower young modulus compared to cobalt and stainless steel alloys. However, compared to bone, young modulus of pure titanium and Ti-6Al-4V are still relatively high and the mechanical properties are still insufficient to meet the needs of biomaterials replacing the hard tissues. In this paper, a newly Ti-Mo-Nb based alloys were designed and the effect of Sn content in Ti-6Mo-6Nb-xSn alloys (x = 0,4,8 and 12 wt%) after homogenized on microstructure, hardness, and young modulus were investigated. The alloys were produced by electric vacuum arc furnace with non-consumable tungsten electrode then homogenized at 1100 °C for 7 under controlled argon atmosphere. Optical microscope, scanning electron microscopy, x-ray diffraction hardness test and ultrasonic test were used for alloys characterization. The results showed that Ti-6Mo-6Nb-xSn has equiaxed structure and Sn addition could promote the formation of β phase. The elasticity modulus of Ti-6Mo-6Nb-xSn alloy with the addition of 12% Sn was 88 GPa, this is better since it is below the elastic modulus of Ti6Al4V implant material.