bluuebunny/crossref_metadata_2025_split huggingface dataset:
Down Syndrome : Through The Eyes of The Parents
Authors: Maritska Ziske , Abdurrahman Fakhri , Prananjaya Bintang Arroyantri , Parisa Nita , Syifa Syifa , Triwani Triwani 
Published: November 2018

Sindroma Down merupakan salah satu kejadian kelainan kromosom tipe aneuploidi yang kerap ditemukan. Kejadian Sindroma Down terkait erat dengan disabilitas intelektual dan stugma sosial yang melekat padanya. Pandangan orang tua mengenai Sindroma Down yang tercerminkan melalui perilaku amat penting karena dukungan keluarga merupakan salah satu kunci utama untuk mengoptimalkan kualitas hidup penyandang Sindroma Down. Studi ini merupakan studi deskriptif pada orang tua penyandang Sindroma Down yang bersekolah di Sekolah Luar Biasa (SLB) di Palembang. Perilaku orang tua diukur dengan menggunakan kuesioner HealthStyles©. Sebagian besar orang tua penyandang Sindroma Down sepakat bahwa anak dengan Sindroma Down harus bersekolah di SLB (82,5%) karena mayoritas meyakini pencampuran penyandang Sindroma Down di sekolah biasa dapat mengganggu murid lain (60%). Namun orang tua memiliki pandangan optimis bahwa anak penyandang Sindroma Down dapat bekerja jika telah dewasa (72,5%). Mereka pun percaya bahwa penyandang Sindroma Down tidak lebih rentan mengalami kecelakaan kerja di tempat kerja (37,5%). Dari studi ini terlihat bahwa orang tua penyandang Sindroma Down memiliki perilaku yang bervariasi tergantung dari aspek mana mereka memandang Sindroma Down.
Effects of Moringa Leaf Extract (Moringaoleifera) in the Breastfeeding
Authors: Septadina Indri Seta , Murti Krisna 
Published: November 2018

Exclusive breastfeeding for 6 months is a global strategies to promote the growth, development, health and survival of infants. Despite the many benefits of exclusive breastfeeding for infants, mothers, families and communities, the coverage is still low in many countries including Indonesia. Mother's milk is produced from the collaboration between mechanical stimulation of hormonal and nerve factors. One of the hormones that affects is the estrogen. The hormone estrogen is a sex hormone produced by the uterus to stimulate the growth of sex organs such as breasts and pubic hair and regulate the menstrual cycle. The hormone estrogen also plays a role to maintain the texture and function of the breast. Pregnancy in a woman, making the breast gland will be more developed by the influence of estrogen, somatomamotropin and prolactin hormones. The process is affected by the hormones estrogen and progesterone. Estrogen significantly stimulates the synthesis and release of pituitary hormone, this effect depends on the duration and dose of administration. In Indonesia, moringa plant is a local food that has the potential to be developed in culinary breastfeeding mothers because it contains phytosterol compounds that function to improve and facilitate the production of breast milk (laktogogum effect). This paper will discuss some of the facts about the effect of Moringaoleifera extract on prolactin levels in increasing the quantity and quality of breast milk in the breastfeeding process. The amount of nutrients in the Moringa leaf (Moringaoleifera) one such as phytosterol compounds (laktogogum effect) in increasing levels of pituitary hormone and iron hormones can have a positive impact on the health of the baby because breast milk is the most important and best natural baby food.
Relationship of Scabies With Pioderma: As a Risk Factor
Authors: Yahya Yulia Farida , Argentina Fifa , Rusmawardiana Rusmawardiana 
Published: November 2018

Scabies is a parasitic infestation of the skin, that is affecting on the low income and crowded community in many tropical countries, especially developing countries such as Indonesia. Scabies infestation increases the incidence of secondary pyoderma include impetigo, folliculitis, cellulitis, ecthyma, abscess. Secondary pyoderma is a skin infection disease mainly caused by group A Streptococcus (GAS) and Staphylococcus aureus (SA). Pyoderma is a risk factor for the glomerulonephritis infection, rheumatic diseases, which significantly increases morbidity and mortality, causing the government burden. The aim of this study is determining the etiology and correlation of pyoderma infection in scabies patient. To determine sosio-demographic included sex, age in pediatric patients in primary schools (SD) in the district of Kertapati Palembang. The study design was cross sectional, and study samples were new scabies patients in the elementary school (age 6-14-year-old) with or without pyoderma. Clinical findings included history, physical examination and diagnostic procedure, which was investigation of skin scraping specimen material (SSB = skin surface biopsy) in confirmation with dermoscopic polar examination (DS) to show Sarcoptes scabiei mites. Microbiological examination with Gram stain identified the etiology of pyoderma. Results of this study shows that there was a significance relationship between scabies infestation and pyoderma in children in elementary school. Staphylococcus aureus dan GAS are the most common caused of pyoderma in pediatric patients with scabies. Conclusion is there is a significant correlation between scabies and pyoderma. There is a need to provide scabies and pyoderma medication at primary care health center as well as counseling for prevention in Palembang area with crowded population periodically.
Biomolecular Characteristics of Amyloid Precursor Protein Mutations As Causes of Alzheimer's Disease Analyzed Through Bioinformatics Media
Authors: Irfannudin Irfannudin 
Published: November 2018

Methods of biomolecular analysis on protein through bioinformatics media has been growing rapidly. This report is intended to describe the results of biomolecular amyloid precursor protein (APP) analysis and the characteristic change of APP mutations causing cognitive degeneration disorder through bioinformatics media and search to reliable biomolecular sites. APP is a transmembrane protein that is widely present in neuronal tissue. APP plays an important role for the formation of neuronal cells. The APP gene is located on the 21st chromosome that has 290,586 base pairs (bp) of 20 exons and 19 introns. In the form of a protein, APP consists of 770 amino acids with major expressions located on the cell surface. Mutation of APP genes is believed to play a role in the incidence of Alzheimer's disease. One of the mutations studied in this paper is the mutation of Alanin to Glysin at the position of the 692 amino acid (APP mutant A692G). This mutation affects the impairment of cerebral amyloid angiopathy belonging to the Alzheimer Disease Familial-1 group.These mutations do not cause changes in predictions of secondary structures and only cause slight changes in molecular weight, amino acid composition, atomic composition, aliphatic index, hydroplasticity and stability index. APP A692G mutation does not alter topology, hydrophobicity, cutting prediction and protein location prediction. Mutation also removes only the side chains at the position of the mutated amino acids.
TO IDENTIFY THE COMPONENT PRESENT IN ASS URINE FOR TREATMENT OF EPILEPSY
Authors: Mishra Anuj 
Published: November 2018

Approximately 150 L of plasma are purified each day by glomerular filtration, tubular secretion, and tubular reabsorption to produce 0.6 to 2.5 L of urine. The amount of urine produced is influenced by environmental temperature, fluid intake, time of day, emotional state, and many other factors.1
The composition of urine reveals much about body function. Metabolic waste products such as carbon dioxide, urea, uric acid, creatinine, sodium chloride, and ammonia are normally present and have no particular pathological significance. The presence of albumin (a protein), glucose, ketones, and various other substances, however, may indicate malfunction of the kidneys or some other organ of the body.1
Biological importance of Ass urine: (Sanskrit :khara; Latin : Asinusequidae) The urine of Ass has been mentioned useful as destroyer of epilepsy (apasmara), intensity (unmada) and in seizures. The mode of its use has been mentioned as internal as drink. Apart from the above mentioned diseases, the urine of Ass has also been prescribed to cure diabetes and various diseases caused by worms.2,3
FORMULATION AND CHARACTERIZATION OF TRANSDERMAL PATCHES OF TOLBUTAMIDE
Authors: Chetna Ms 
Published: November 2018

The Skin is one of the most extensive organs of the human body. This multilayered organ receives approximately one-third of all blood circulating through body. With a thickness of about a millimeter, the skin separates the underlying blood circulation network from the outside environment1.
Transdermal delivery of drugs through the skin to the systemic circulation provides a convenient route of administration for a variety of clinical indications. Transdermal delivery systems are currently available containing scopolamine (hyoscine) for motion sickness, clonidine and nitroglycerin for cardiovascular disease, fentanyl for chronic pain, nicotine to aid smoking cessation2.
Drug molecules in contact with the skin surface can penetrate by three potential pathways: through the sweat ducts, via the hair follicles and sebaceous glands (collectively called the shunt or appendageal route), or directly across the stratum corneum3.

All transdermal drug delivery systems consist mainly of:

Polymer matrix
Drug
Enhancers and other excipients

Other excipient
Perbedaan Peran Ibu Primipara Dan Multipara Dalam Pengasuhan Bayi Baru Lahir
Authors: Hardjito Koekoeh , Antono Sumy Dwi , Yani Erna Rahma 
Published: November 2018

Primipara mother is woman which has borned a baby aterm the first time. However multipara mother is woman which has been borned life a baby several times but it is not more than five times. Primiparous response as parents need more support from the environment and some women do not like to responsibilities at home and care for the baby. Whereas in multiparous would be more realistic in anticipating his physical limitations and can more easily adapt to the role of social interaction, in the sense of having a positive response as a parent. The role of both in interaction and mothering of newborn baby were observationed either from feeding, interest, respons, speech and touch by FIRST observation method. Many things influencing interaction and ability of mother and mothering baby, one of them are experience of mother bears and takes care of child before it. This research aim to see is there are many difference the role of primipara and multipara mother in mothering of newborn baby that analized with FIRST observation method. Research design used study comparative with design sistematic of random sampling technic for gathering of the sample. Obsevation has been to 53 mother of post partum that consisted of 25 primipara and 28 multipara in Aura Syifa Hospital at Kediri. These observation has been done once between first day up to seventh day after delivering birth. Testing of data was done by Man-Whitney U Test with p value= 0,036 (α= 0,05). The result of research showed there are difference significantly between the role of mother primipara and multipara in mothering of newborn baby. Interaction between mothers with baby and mothering pattern of newborn baby are multipara mother better than primipara mother with FIRST observation method.; Key word: the role, primipara, multipara, mothering
Hubungan Antara Status Gizi (IMT) dengan Usia Menarche pada Remaja Putri Usia 13-14 Tahun di SMPN 1 Pace Kecamatan Pace Kabupaten Nganjuk
Authors: Antono Sumy Dwi 
Published: November 2018

The average of menarche young women continoued to decline on average about 3-4 months every 10 years. The shift of the age of menarche to younger age can cause emotional stress, the risk of breast cancer, pregnancy is noy on purpose. The purpose of this research is to know the relationship between nutritional status with age of menarche in young women aged 13-14 years. The type of this research use cross sectional research design. Sampling technique of this research used proportional stratified random sampling which the research took a random strata in the population, for this research the reseacher using the lottery draw. The researcher abtained samples of 76 responden of total student population of 96. The analysis data of this research is Spearman Rank. The result of the analysis data shows that there is no relationship between nutritional status with age of menarche which the value tcount = 0,647 less than ttable = 1,995. For this research the researcher gives suggestion to the next researcher to develop the factor social media that can influence the age of menarche in girls forther.; Keywords : nutritional status, age of menarche, young women
Effect of timing cord clamping on a vaginally delivered infant of a primigravida in terms of the incidence of hyperbilirubinemia
Authors: Setyaningsih Maria Magdalena , Anugrahanti Wisoedhanie Widi 
Published: November 2018

Delayed cord clamping leads to the increased level of haematocrite and victocytes which is high risk of hyperbilirubinemia . This study is to determine if there is an effect of timing of cord clamping relating to the incidence of hyperbilirubinemia on newborn, and to create formulating the standard procedures in maternal interventions related to the timing of cord clamping, another objective is preventing interventions of its occurrence when the clamping is performed immediately after birth. Crossectional study was applied design of the research. Population and samples included infants spontaneus by healthy primigravidas.Two trials were included, 20 participants of each received interventions of cord clamping more than equalivalent 1 minute and less than 1 minute followed by bilirubin assessment 48 hours after birth, and analysed by using Linier Regression. There is no significant effect of timing of cord clamping on newborn with regard to hiperbilirubinemia, because the effect of the clamping on bilirubin level reaches up to 68.2%, while the other 31.8% of the varying levels are affected by other factors. There is a need to conduct other relevant studies aimed to prevent hyperbilirubinemia starting from antenatal to postnatal stage.; Key Words: Jaundice, Newborn, Hyperbilirubinemia, Time of Clamping, Primigravidas
Hubungan Senam Kegel Pada Ibu Hamil Primigravida TM III Terhadap Derajat Robekan Perineum Di Wilayah Puskesmas Pembantu Bandar Kidul Kota Kediri
Authors: Kristianti Shinta , Putriyana Yohanita 
Published: November 2018

Chiilddbirt injuries often result in the birtht canal, or tearing of the perineum or perineum rupture. Perineum laceration can be caused by maternal parity, estimated fetal weight, and so on becaused the perineum is elastic, but can also be found on the perineum rigid, especially on the first pregnancy (primigravida). Doing Kegel exercises can increase elastisitasion maternal perineum area. Kegel exercises to strengthen pelvic muscles before delivery, and can flex muscle of perineum as delivery baby. The purpose of this study was to determine the relationship of kegel exercises for pregnant women primigravida TM III with the degree of rupture perineum on normal deliveries at Puskesmas Bandar Kidul district of kediri. The design of this study using Analitic Correlation study with cross- sectional approach. Population from this study were 19 respondent and Samples were 16 respondents pregnant women primigravida TM III with Consecutive Sampling. Instrument in this study using a cheklist sheet and observation sheets. From the result, the results of most respondents do kegel exercise with frequency =5x each day. From the analysis of the data using the Spearman Rank r count showed 0.12 ; t table 0.506 means Ho received no relationship kegel exercise with degree of rupture perineum in Puskesmas Bandar Kidul of Kediri. Kegel execises should be done on healing perineal wound.; Keywords : Kegel exercises, Primigravida, Degree of rupture perineum
Perbedaan Tingkat Pemenuhan Kebutuhan Tidur Pada Lansia Sebelum Dan Sesudah Pemberian Teknik Relaksasi Benson Di Panti Sosial Lanjut Usia Pare Kabupaten Kediri Tahun 2012
Authors: Rahayu Kun Ika Nur 
Published: November 2018

Elderly is the last phase of everyone’s life cycle, where they got change biologically, pshycologically, and socialy. Commonly, the elderly got disturbance in quality and quantity sleep needed. Sleeping is a basic needed of all human to be functioned well. According to Luce and Segal (2000). There is 22% elderly cases whose wake up earlier (less than 05.00 p.m) for the elderly in 70 th. Beside, there is 30% for the elderly in 70 th whose wake-up at midnight. One of the solution to solve the problem is using Benson Relaxation technique. This technique can solve the sympthom of sleeplessness such as insomnia, pain and anxiety. The purpose of this research is to know the different the fulfil of sleep needed for elderly before and after giving Benson Relaxation technique in Geriatric Clinic “Lanjut Usia” Pare Kediri in 2012. The research design is pre experimental with one group pre and post test design. The population is elderly in 60-74 years old who got sleeplessness but still can communicate well. The sample is 30 person the sample taken used purposive sampling. It used questionnaire instrument to know the sleep needed of elderly. Then the data analyzed using statistic Willcoxon. The result show, the fulfil of sleep needed for elderly before giving Benson technique is 83% while after giving is 77%. Based on statistic test is gotten ρ=0,00 with α = 0,05. So ρ ; α, Ho is rejected. It means, there is the deferent of sleep needed level before and after giving Benson Relaxation technique can be used for nurses to solve the problem of sleep for elderly.;Keywords : elderly, sleep, Benson Relaxation
Corelation Anemia Status With Learning Achievment Of The Second Level Under Graduate Students Of Dharma Husada Nursing Academy Kediri
Authors: Santoso Puguh 
Published: November 2018

experience by individuals. One of the internal factors that have a correlation with learning achievement is Another factor related with a physical condition that impairs the ability to learn, one of which is anemia. This research aim to analyze the correlation between anemia status on the sekond-level of undergraduate students of Dharma Husada Nursing Academy Kediri. Population of this research was the third-level of undergraduate student of Dharma Husada Nursing Kediri academic year of 2014 / 2015, which consists of two classes. Samples were taken using simple random sampling technique and found 91 subjects. Haemoglobin level data was obtained using cyanmethemoglobin measurement method and learning achievement data was obtained using learning documentation. Data were analyzed with bivariate tests using simple regression with a confidence level of 95% (α=5%). of the second-level undergraduate students of Dharma Husada Nursing Academy Kediri (p=0,014). achievement of the second-level undergraduate students of Dharma Husada Nursing Academy Kediri. Contribution anemia status on learning achievement were 2,9%, while 97,1% were related to another factor that were not analyzed in this research.; Keywords: Students, Anemia Status, Learning Achievement
La pesadilla americana, o la revelación de lo extraño en tres documentales de Werner Herzog
Authors: Zavala Scherer Diego 
Published: November 2018

El presente artículo analiza tres obras de la filmografía de Werner Herzog: How Much Wood Would a Woodchuck Chuck (1976), Huie’s Sermon (1981) y God’s Angry Man (1981) a partir del uso del plano secuencia como dispositivo documental. A pesar del vínculo de esta forma de puesta en cámara con el cine directo, Herzog deconstruye su uso para la generación de momentos de revelación fílmica, lejos del simple registro.
العلاقة السببية بين حجم المديونية والقيمة الاقتصادية المضافة في ظل تباين حجم المنشأة
Authors: هاشم صبيحة قاسم , كريم مهدي عبد الحسين 
Published: November 2018

المستخلص
يهدف البحث الى التعرف على طبيعة العلاقة القائمة بين مستوى الديون المستخدمة والقيمة الاقتصادية المضافة للشركات المدرجة في سوق العراق للأوراق المالية في ظل تباين احجام تلك الشركات ، وقد تناول البحث المفاهيم النظرية المرتبطة بكل من التمويل بالدين والقيمة الاقتصادية المضافة وحجم المنشأة مع استخدامه الاساليب المالية في الجانب التطبيقي لقياس تلك المتغيرات ، وتمثل مجتمع البحث بالشركات المساهمة المدرجة في سوق العراق للأوراق المالية مع اختيار عينة عمدية مكونة من 24 شركة مساهمة تمثل ما يقارب نسبة 27% من مجتمع البحث بعد تحقيقها لشروط معينة وللفترة الزمنية من ( 2013 - 2008 ) واستخدمت مجموعة من الاساليب الاحصائية في تحليل العلاقة بين المتغيرات واختبار فرضيات البحث هي نموذج الانحدار الخطي بنوعيه البسيط والمتعدد ، معامل ارتباط بيرسون ، معامل التحديد ، تحليل التباين الاحادي ANOVA فضلا عن اجراء كل من اختباري t و f بغرض تحديد المعنوية الاحصائية للعلاقة بين المتغيرات . وتوصلت نتائج البحث الى وجود تأثير معنوي لحجم الديون المستخدمة في القيمة الاقتصادية المضافة وان هذا التأثير يزداد مع دخول حجم المنشأة كمتغير ثالث في نموذج الاختبار الخاص بتلك العلاقة ، كما واظهرت النتائج ايضاً وجود اختلافات واضحة في القيمة الاقتصادية المضافة بين شركات العينة خلال السنوات الست للدراسة وبناء على ذلك اوصى البحث بضرورة اهتمام ادارة الشركات بالمناهج المستندة الى القيمة في قياس ارباحها المتحققة ، واهمية ادراكها للأثر الايجابي الناتج عن استخدام النسب الملائمة من الديون في تعظيم ثروة المساهمين والقيمة المضافة للشركة ككل .
تطوير نظام إدارة النفايات الصلبة ((بحث تطبيقي في مدينة الحلة))
Authors: جثير سعدون حمود 
Published: November 2018

المستخلص
يهدف البحث الى الوقوف على الواقع العملي لعمليات ادارة النفايات الصلبة في مدينة الحلة التي تقوم بها مديرية بلدية الحلة – شعبة المخلفات الصلبة والبيئة ، من خلال الزيارات الميدانية والمقابلة الشخصية لمسؤولي الاقسام البلدية والوحدات التابعة لها وجمع البيانات والمعلومات المتعلقة بالنفايات الصلبة ، وتقييم الوضع الحالي لعمليات الجمع والنقل للنفايات من خلال الاستبانة التي تم اعدادها للمواطنين والموظفين، وتوصل البحث الى مجموعة من الاستنتاجات كانت اهمها ، العمليات التي تقوم بها مديرية بلدية الحلة تقتصر فقط على عمليتي (الجمع والنقل والتخلص من النفايات في موقع مفتوح) وانها لا تعمل بالشكل المطلوب ، بسبب العديد من المشاكل التي يمكن حصرها بالمالية ، المادية والبشرية ، ووجود رغبة جادة وحقيقية لعملية فرز النفايات من قبل المواطن في حال توفر المستلزمات الضرورية ، وان موقع الطمر الحالي له العديد من الاضرار البيئية والصحية بسبب موقعه غير المناسب وعمله الذي لا يكون على وفق الاليات الهندسية والفنية القياسية المعمول بها دولياً.
واستناداً الى ما توصل اليه البحث من نتائج فقد وضعت مجموعة من التوصيات اهمها اعداد دراسة دقيقة من قبل مديرية بلدية الحلة حول ما ينتجه الفرد يومياً من النفايات وتحديد وتصنيف انواع النفايات لما لها اثر كبير في مراحل ادارة النفايات ، واعداد برامج ودورات تطويرية عن الادارة المتكاملة للنفايات الصلبة للموظفين والعاملين ، وتوعية وتشجيع المواطن على ضرورة الفرز الاولي للنفايات من قبله.