bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of pickle from Thai pangus (Pangasianodon hypophthalamus) muscle and changes in it’s nutritional composition during storage
Authors: Shikha Fatema Hoque , Hossain Md. Ismail , Akter Khaleda , Rahman Md. Arifur 
Published: December 2018

Fish pickle was developed from Thai pangus (Pangasianodon hypophthalamus) fish muscle by using different types of food additives. Mustard oil and soybean oil were used for preparing fish pickle. Dorsal muscle and whole fish muscle without bone were used as raw material for preparing fish pickle. Changes in nutritional composition, pH, bacteriological and sensory attributes were determined at room temperature (30–35°C) according to standard procedures. At room temperature (30-35°C) fish pickle prepared from dorsal muscle and whole fish muscle using both mustard oil and soybean oil remained in acceptable condition until 12/13 days. Bad smell produced in the pickle after 15th day of storage. Moisture, protein, lipid and pH value decreased but ash content increased with the progress of storage period. In case of soybean oil used pickle deterioration was faster than the pickles prepared using mustard oil. Bacterial load was higher in soybean oil pickle and the pickle prepared from whole fish muscle.
J. Bangladesh Agril. Univ. 16(3): 545–552, December 2018
Visian Collamer Phakic Intraocular Lens in High Myopic Asian Eyes
Authors: Chang John S , Meau Andy Y 
Published: December 2018

ABSTRACT
PURPOSE: To evaluate the safety and efficacy of the Implantable Collamer Lens (Visian), a phakic intraocular lens (PIOL), in the correction of high myopia in Asian eyes.
METHODS: This prospective study comprised 61 eyes in 40 Chinese patients with mean preoperative manifest spherical equivalent refraction of -14.54±3.61 diopters (D) (range: -7.00 to -24.75 D) who underwent Visian PIOL implantation from May 2002 to December 2004. The anatomical differences between Asian and Caucasian eyes were compared.
RESULTS: Mean follow-up was 13.67±8.51 months (range: 1 to 32 months). Predictability of the manifest spherical equivalent refraction to within ±1.00 D was achieved in 88% of eyes and ±0.50 D in 72.5% of eyes. The mean postoperative manifest spherical equivalent refraction was -0.10±0.74 D, with 97% of eyes maintaining or gaining ≥1 lines of best spectacle-corrected visual acuity (BSCVA). Two eyes lost 1 line of BSCVA. Retinal detachment developed in 1 eye 15 months after initial surgery. Because of the statistical differences in anterior chamber depth and white-to-white distance between Caucasian and Chinese eyes, the Visian PIOL size was more accurate if the calculation was modified so that 0.5 mm was added to the white-to-white measurement if the anterior chamber depth was ≤3.0 mm and 1.0 mm to the white-to-white measurement if the anterior chamber depth was >3.0 mm. Initial incorrect sizing using the original nomogram led to the only cataract in our series.
CONCLUSIONS: The implantation of the Visian PIOL for correcting moderate to high myopia in Asian eyes shows similar safety and efficacy to the FDA clinical trial of Caucasian eyes. Proper sizing of the Visian PIOL is important and differs slightly in Asian eyes. [J Refract Surg. 2007;23:17-25.]
Surface Wave Elastometry of the Cornea in Porcine and Human Donor Eyes
Authors: Dupps William J , Netto Marcelo V , Herekar Satish , Here Ronald R 
Published: December 2018

ABSTRACT
PURPOSE: To introduce a nondestructive technique for characterization of corneal stiffness, determine measurement precision, and investigate comparative stiffness values along central, radial, and circumferential vectors in porcine corneas. The effects of epithelial debridement, relaxing incisions, and crosslink-mediated stiffening on surface wave velocity are also studied.
METHODS: A handheld prototype system was used to measure ultrasound surface wave propagation time between two fixed-distance transducers along a ten-position map. Repeatability was assessed with replicate measurements in 6 porcine corneas. In 12 porcine globes with controlled intraocular pressure (IOP), serial measurements were performed before and after epithelial removal, then after 250- and 750-µm-deep relaxing incisions. In human globes with constant intravitreal pressure, central wave velocity and transcorneal IOP measurements were compared before and after collagen cross-linking.
RESULTS: Measurement repeatability across all regions was between 2.2% and 8.1%. Epithelial removal resulted in increases in measured stiffness in 67% of eyes, but statistical power was insufficient to detect a systematic change. Wave velocity across a central incision decreased significantly after 250-µm keratotomy (P<.001), but did not undergo a significant further decrease with deeper keratotomy. Meridional stiffness changes consistent with coupling effects were detected after keratotomy. Surface wave velocity and transcorneal IOP measurements increased markedly after collagen cross-linking despite maintenance of a constant IOP
CONCLUSIONS: Handheld corneal elastometry provides a repeatable measure of regional stiffness changes after relaxing incisions and collagen cross-linking in in vitro experiments. Surface wave elastometry allows focal assessment of corneal biomechanical properties that are relevant in refractive surgery, ectatic disease, and glaucoma. [J Refract Surg. 2007;23:66-75.]
Corneal Hysteresis, Resistance Factor, Topography, and Pachymetry After Corneal Lamellar Flap
Authors: Gatinel Damien , Chaabouni Slim , Adam Pierre-Alexandre , Munck Jacques , Puech Michel , Hoang-Xuan Thanh 
Published: December 2018

ABSTRACT
PURPOSE: To measure prospectively the early changes in corneal hysteresis, topography, and pachymetry after the creation of a stromal flap cut without laser photoablation.
METHODS: A 37-year-old man was referred for a bioptic procedure to correct for compound myopic astigmatism in the left eye. A 159-µm-thick 8×8.5-mm superior hinged flap was created with a mechanical microkeratome in the left cornea. Changes in the corneal hysteresis, corneal resistance factor, Goldmann correlated intraocular pressure (IOP), corneal compensated IOP, anterior and posterior topography, and optical and ultrasound pachymetry were monitored prospectively before and at 1 hour, 1 day, 5 days, and 25 days after flap creation. The right eye served as a control.
RESULTS: In the left eye, corneal hysteresis and corneal resistance factor decreased immediately after the flap cut and remained lower than preoperatively at 1 hour, 1 day, 5 days, and 25 days. Corneal compensated IOP varied significantly less than Goldmann correlated IOP in both eyes. Central flattening of the horizontal meridians was observed on the difference topography maps. The values of the left eye posterior best fit sphere increased after the flap cut. Increased central corneal thickness occurred immediately after the flap cut and decreased over time without returning to its preoperative value.
CONCLUSIONS: The creation of a stromal flap can modify the biomechanical properties of the cornea, including a reduction in corneal hysteresis. The topographic changes were consistent with previously reported cases of flap cut in normal corneas. [J Refract Surg. 2007;23:76-84.]
How Might Corneal Elasticity Help Us Understand Diabetes and Intraocular Pressure?
Authors: Krueger Ronald R , Ramos-Esteban Jerome C 
Published: December 2018

ABSTRACT
PURPOSE: To determine how changes in corneal elasticity/stiffness might influence intraocular pressure (IOP) readings in diabetic patients.
METHODS: A systematic review of the literature was performed to understand the conflicting relationship between diabetes, elevated IOP, and glaucoma progression.
RESULTS: Diabetic patients have been found to have statistically significant higher IOP readings in some population-based studies compared to non-diabetics. Insulin resistance states, hyperglycemia and glycosylated hemoglobin have been correlated with higher IOP (1 mmHg) measurements in diabetic patients. In the Ocular Hypertension Treatment Study (OHTS), a self reported history of diabetes was found to be protective against the progression of primary open-angle glaucoma. Small differences in IOP measurements in diabetic patients may be due to corneal stiffening, as demonstrated by the protective effect of glucose-mediated collagen cross-linking against the manifestation and keratometric progression of keratoconus. Different collagen cross-linking agents may induce different degrees of corneal stiffening, which can result in differences in measured IOP.
CONCLUSIONS: Glucose-mediated corneal stiffening due to collagen cross-linking might be responsible for IOP overestimation in diabetic patients. Corneal stiffening might explain why diabetic eyes tend to have higher IOP readings in large population-based studies and why those with ocular hypertension have a reduced risk for glaucoma progression. [J Refract Surg. 2007;23:85-88.]
Corneal Ectasia After Hyperopic LASIK
Authors: Randleman J Bradley , Banning Christopher S , Stulting R Doyle 
Published: December 2018

ABSTRACT
PURPOSE: To report two cases of corneal ectasia, which developed after hyperopic LASIK.
METHODS: Preoperative pellucid marginal corneal degeneration was observed in patient 1. Patient 2 had no preoperative risk factors.
RESULTS: Patient 1, a 47-year-old man, developed corneal ectasia in his right eye 6 months after unilateral hyperopic LASIK. Preoperative manifest refraction was +2.00 +1.50 × 178 in the right eye and +1.00 sphere in the left eye. Corneal thickness was 585 µm and 575 µm (right and left eye, respectively). Preoperative topography of the right eye demonstrated inferior steepening in the far periphery, suggestive of early pellucid marginal corneal degeneration. Patient 2, a 35-year-old man, developed corneal ectasia in his right eye >3 years after bilateral LASIK. Preoperative manifest refraction was +2.50 sphere and +3.25 sphere (right and left eye, respectively), and corneal thickness was 556 µm in both eyes. Preoperative topography was normal in both eyes with no evidence of asymmetry, steepening, or irregularity.
CONCLUSIONS: Corneal ectasia can occur after hyperopic LASIK in patients with or without recognized preoperative risk factors. Although uncommon, patients with pellucid marginal corneal degeneration can have hyperopic refractions and are at high risk for developing corneal ectasia after LASIK. [J Refract Surg. 2007;23:98-102.]
Topography-guided Ablation for Treatment of Patients With Irregular Astigmatism
Authors: Toda Ikuko , Yamamoto Takahiro , Ito Mitsutoshi , Hori-Komai Yoshiko , Tsubota Kazuo 
Published: December 2018

ABSTRACT
PURPOSE: To evaluate the customized aspheric treatment zone (CATz) topography-guided ablation for the correction of irregular astigmatism induced by initial corneal refractive surgery or corneal injury.
METHODS: CATz ablation was performed on 32 eyes of 28 patients. Each procedure was performed by photorefractive keratectomy (PRK) or LASIK using a NIDEK EC-5000 excimer laser. The eyes had decentered ablations, small optical zones, decreased best spectaclecorrected visual acuity (BSCVA), and asymmetrical astigmatism. Subjective symptoms, uncorrected visual acuity (UCVA), BSCVA, refraction, corneal topography, and higher order aberrations were measured. Mean follow-up was 161.9± 129.9 days (range: 90 to 492 days).
RESULTS: Data obtained at final postoperative followup show that UCVA and BSCVA increased by >2 lines after CATz ablation in 17 and 11 eyes and decreased in 4 and 2 eyes, respectively. Higher order aberrations were decreased in 16 eyes and increased in 1 eye. Topographical maps were improved with decreased surface regularity index (20 eyes) and surface asymmetry index (22 eyes). Seven eyes required further enhancement for residual refractive errors. Thirteen patients (15 eyes) claimed they were satisfied with the outcome, 6 patients (7 eyes) stated that the outcome was lower than expected, and 4 patients (4 eyes) stated they were dissatisfied.
CONCLUSIONS: CATz topographic ablation effectively improves the quality of vision and symptoms in the majority of patients with irregular corneal astigmatism from previous excimer laser refractive surgery. However, residual or induced refractive errors may need to be corrected with a second operation after CATz. [J Refract Surg. 2007;23:118-125.]
Early Postoperative Pain Following Epi-LASIK and Photorefractive Keratectomy: A Prospective, Comparative, Bilateral Study
Authors: Torres Luis F , Sancho Cristhian , Tan Bryan , Padilla Karina , Schanzlin David J , Chayet Arturo S 
Published: December 2018

ABSTRACT
PURPOSE: To compare postoperative pain associated with epi-LASIK versus photorefractive keratectomy (PRK).
METHODS: This prospective observer-masked randomized study included 40 eyes of 20 patients with myopia and astigmatism who received epi-LASIK (Moria Epi-K) in one eye and PRK in the contralateral eye. Corneal ablation was done using the NIDEK EC-5000 excimer laser. Patients were seen at days 1, 3, and 6 to rate their pain via three measuring tools: 1) a global subjective rating, 2) a 10-cm visual analog scale, and 3) an 11-point numeric scale of pain.
RESULTS: On postoperative day 1, 19 of 20 patients reported pain in both eyes. Using the global subjective rating scale, patients reported more pain for those eyes treated by PRK. Although clinically relevant, this difference was not statistically significant (P=. 56). Based on the 11-point numeric scale of pain and visual analog scale, mean pain scores were similar for both groups. On day 3, using the global subjective rating scale, 11 of 12 patients who had pain reported more in the epiLASIK treated eye (P= .0005). In addition, epi-LASIK eyes demonstrated higher mean pain scores based on the other two scales (visual analog scale, P= .045 and 11-point numeric scale of pain, P= .023). Only 6 patients reported minimal pain on day 6. It was more frequently reported and slightly more marked in epi-LASIK eyes, but did not reach statistical significance.
CONCLUSIONS: Epi-LASIK and PRK have similar pain on postoperative day 1, but epi-LASIK demonstrated statistically more pain than PRK on days 3 and 6. [J Refract Surg. 2007;23:126-132.]
Endothelial Cell Loss After Toric Iris-fixated Phakic Intraocular Lens Implantation: Three-year Follow-up
Authors: Tehrani Mana , Dick H Burkhard 
Published: December 2018

ABSTRACT
PURPOSE: To study quantitative changes in endothelial cell count after implantation of the toric iris-fixated phakic intraocular lens.
METHODS: A prospective, non-randomized, self-controlled clinical trial was conducted of 40 eyes (28 myopic, 12 hyperopic) of 23 patients with high ametropia and astigmatism. Non-contact computer-assisted endothelial microscopy was performed before and I1 2, and 3 years after surgery.

RESULTS: In the myopic group, mean preoperative endothelial cell count was 3179±531 cells/mm
p 2
(range: 1800 to 3900 cells/mm2). The mean intraindividual endothelial cell loss was -1.83±2.25% (range: -9.09% to 0%) in the first year; -1.83+2.95% (range: -7.74% to 3.80%) in the second year; and -3.20±4.43% (range: -14.25% to 1.91%) three years after surgery, compared to preoperative values. In the hyperopic group, mean preoperative endothelial cell count was 3107 ±125 cells/mm2 (range: 2932 to 3300 cells/mm2). The mean endothelial cell loss was -1.63+1.76% (range: -3.23% to 1.67%) in the first year; -0.05+1.25% (range: -1.65% to 1.75%) in the second year; and -2.88±2.03% (range: -5.33% to -0.13%) three years after surgery, compared to preoperative values.

CONCLUSIONS: Annual cumulative cell loss was -1.9% for the myopic group and -1.6% for the hyperopic group, which is two to three times greater than physiological annual cell loss in normal eyes without surgery. An annual endothelial cell count analysis is highly recommended in every patient after iris-claw lens implantation to detect potential progressive cell loss at an early stage. [J Refract Surg. 2007;23:172-177.]
Contrast Sensitivity After LASIK Flap Creation With a Femtosecond Laser and a Mechanical Microkeratome
Authors: Montés-Micó Robert , Rodríguez-Galietero Antonio , Alió Jorge L , Cerviño Alejandro 
Published: December 2018

ABSTRACT
PURPOSE: To compare the effects on contrast sensitivity of the IntraLase femtosecond laser for flap creation (IntraLASIK) and standard LASIK for myopia.
METHODS: Two hundred eyes of 100 consecutive patients underwent LASIK treatment using the VISX S2 laser system. The femtosecond laser (15 kHz IntraLase) was used for flap creation in 100 eyes (50 patients) and a mechanical microkeratome (Carriazo-Barraquer) was used in 100 eyes (50 patients). Best spectacle-corrected contrast sensitivity was measured before and 6 months postoperatively in the IntraLASIK and mechanical LASIK groups. The IntraLASIK and mechanical LASIKinduced changes in contrast sensitivity were compared under photopic (85 cd/m2) and mesopic (5, 2.5, and 0.1 cd/m2) conditions.
RESULTS: Contrast sensitivity for eyes after IntraLASIK did not differ from preoperative values at the photopic level (85 cd/m2). However, under mesopic conditions, a statistically significant reduction (P<.01) in contrast sensitivity was found at high spatial frequencies (12 and 18 cpd), although no significant contrast sensitivity differences were observed at low and middle spatial frequencies (P>.01 for 1.5, 3, and 6 cpd). No statistically significant differences were found between IntraLASIK and mechanical LASIK for 1.5,3, and 6 cpd at any luminance level (P>.01). IntraLASIK showed better contrast sensitivity than mechanical LASIK under mesopic conditions at 12 cpd and photopic and mesopic conditions at 18 cpd (P<.01).
CONCLUSIONS: IntraLASIK surgery demonstrated better contrast sensitivity at high spatial frequencies under photopic and mesopic conditions than mechanical LASIK. [J Refract Surg. 2007;23:188-192.]
Retreatment of Hyperopia After Primary Hyperopic LASIK
Authors: Ortega-Usobiaga Julio , Cobo-Soriano Rosario , Llovet Fernando , Ramos Francisco , Beltrán Jaime , Baviera-Sabater Julio 
Published: December 2018

ABSTRACT
PURPOSE: To evaluate factors that influence retreatment results after primary hyperopic LASIK.
METHODS: Restrospective study of 86 eyes of 61 patients that underwent LASIK to correct primary hyperopic spherical equivalent refraction and a second hyperopic retreatment due to undercorrection. All procedures were performed with the Technolas Keracor 217C excimer laser, lifting the preexisting flap for the retreatment. Preoperatively, under cycloplegia, mean spherical equivalent refraction of the series was +3.05±0.99 diopters (D).
RESULTS: At last follow-up, mean spherical equivalent refraction was -0.07 ±0.50 D. Efficacy of the retreatment procedure was better when the primary LASIK attempted spherical equivalent refraction correction was <+3.00 D (P<.05). Safety of retreatment was lower when attempted spherical equivalent refraction correction was >+1.00 D (P<.05) and when attempted spherical equivalent refraction correction of both procedures combined was >+4.00D(P<.05).
CONCLUSIONS: Efficacy, safety, and predictability of retreatments secondary to undercorrection after primary hyperopic LASIK may be affected depending on the amount of diopters corrected in the primary procedure, in the retreatment procedure, and in both primary and retreatment procedures combined. [J Refract Surg. 2007;23:201-205.]
Tear Volume and Stability After LASIK
Authors: Patel Sudi , Alió Jorge L , Artola Alberto , Martinez Maria-Jose 
Published: December 2018

ABSTRACT
PURPOSE: To monitor tear volume and tear film stability before and after LASIK.
METHODS: Tear meniscus height at the mid-point above the lower eyelid and tear thinning time were measured using videokeratography in both eyes before bilateral LASIK and at 1, 3, and 6 months postoperatively. Patients predisposed to dry eye before surgery were excluded.
RESULTS: Twenty-six patients (52 eyes) were monitored. Mean tear meniscus height values were: preoperative, 0.26+0.09 mm; 1 month, 0.24±0.07 mm; 3 months, 0.26±0.07 mm; and 6 months, 0.26+0.06 mm. The differences were not significant. Change in tear meniscus height at 1 month was 0. 1395-0. 601[preoperative tear meniscus height] (r= -0.701, P<.0001, n=52). On average, tear thinning time was not affected by LASIK. When preoperative tear thinning time was <20 seconds, individual changes in tear thinning time at 3 and 6 months were significant (P<.05) but not at 1 month (P= .206).
CONCLUSIONS: Average tear meniscus height and stability are not affected by LASIK; however, there is considerable variability between individual eyes. [J Refract Surg. 2007;23:290-298.]
A 60 kHz IntraLase Femtosecond Laser Creates a Smoother LASIK Stromal Bed Surface Compared to a Zyoptix XP Mechanical Microkeratome in Human Donor Eyes
Authors: Sarayba Melvin A , Ignacio Teresa S , Tran Dan B , Binder Perry S 
Published: December 2018

ABSTRACT
PURPOSE: To compare the stromal surfaces created by the latest mechanical microkeratome and femtosecond laser technologies.
METHODS: Laser in situ keratomileusis (LASIK) flaps were created in six fresh human globes unsuitable for transplantation. The eyes were placed in one of two groups of three globes each. One group had LASIK flaps created with a Zyoptix XP microkeratome using a 120-µm head and a fresh blade for each eye. Another group had flaps created at an attempted 100-µm thickness using the 60 kHz IntraLase femtosecond laser. Immediately following flap creation, the stromal beds were prepared for scanning electron microscopy (SEM). Qualitative roughness of the SEM images was graded by masked observers. Quantitative roughness of the SEM images was assessed using computerized software designed for roughness analysis. Mann-Whitney non-parametric statistical analysis was performed to compare groups.
RESULTS: A statistically significant difference was noted in bed smoothness as measured by qualitative roughness and quantitative roughness scores. The IntraLase samples showed smoother stromal beds compared to the Zyoptix group (qualitative roughness = 2.0+0.7 pm vs 3.6+1.6 pm, P= .03; quantitative roughness = 20238+1869 pm vs 26368+8133 pm, P= .03).
CONCLUSIONS: The 60 kHz IntraLase femtosecond laser and the Zyoptix XP 120-µm head using a new blade produced smooth, good quality, compact stromal beds qualitatively and quantitatively. Because the 60 kHz femtosecond laser permits a tight spot/line separation using low energy, it creates a smoother corneal stromal bed compared to previous femtosecond laser engines. [J Refract Surg. 2007;23:331-337.]