bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERAN AL WARAQ DALAM INDUSRI PENERBITAN BUKU ISLAM DAN DAMPAKNYA TERHADAP PERKEMBANGAN KEILMUAN ISLAM
Authors: Santoso Budhi 
Published: July 2019

Introduction. This article discusses intellectual development in the Islamic world and the role of al-Waraq in the Islamic book publishing industry.
Data Collection Method. The method used in this article is the literature study method used in obtaining data.
Analysis Data. The data obtained is then grouped according to relevance to the formulation of the problem
Results and Discussions. The copying of scientific texts is very instrumental in the spread of knowledge, besides being a copyist of the Al Warraq manuscript, it also acts as editor and publisher of books. that. With the existence of this catalog, we can find out the number of publications at the time and as literature for the study of Muslim works in the golden era. Copyright licenses are issued to avoid plagiarism or recognition of a work by Al Warraq. The Al Warraq profession was slowly displaced by the discovery of printing technology in the fifteenth century.
Keyword: al warraq, Islamic scientific development, Islamic Book Publishing Indusrial
PENGEMBANGAN MODUL BERBASIS GUIDED DISCOVERY PADA MATERI SISTEM PERNAPASAN UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS SISWA KELAS XI SMA NEGERI 5 SURAKARTA
Authors: Suryani Nina Teja , Prayitno Baskoro Adi , Rinanto Yudi 
Published: July 2019

Penelitian ini bertujuan untuk: 1) mengembangkan modul dengan karakteristik <em>guided</em><em> discovery </em>pada materi Sistem Pernapasan untuk meningkatkan kemampuan berpikir kritis siswa kelas XI SMA Negeri 5 Surakarta; 2) menguji kelayakan modul berbasis <em>guided discovery</em> pada materi Sistem Pernapasan untuk meningkatkan kemampuan berpikir kritis siswa kelas XI SMA Negeri 5 Surakarta; dan 3) menguji keefektivan modul berbasis <em>guided discovery </em>pada materi Sistem Pernapasan untuk meningkatkan kemampuan berpikir kritis siswa kelas XI SMA Negeri 5 Surakarta. Penelitian ini menggunakan metode <em>Research and Development</em> (R &amp; D) mengacu pada Borg dan Gall (1983) yang dimodifikasi menjadi sembilan tahapan yaitu: 1) penelitian dan pengumpulan informasi; 2) perencanaan; 3) pengembangan produk awal; 4) uji coba lapangan tahap awal; 5) revisi produk awal; 6) uji lapangan terbatas; 7) revisi produk kedua; 8) uji lapangan operasional yang menggunakan desain penelitian kuasi eksperimen; dan 9) revisi produk akhir. Analisis data yang digunakan adalah analisis deskriptif, teknik persentase dan uji <em>Independent Samples T Test</em>. Hasil penelitian menunjukkan: 1) karakteristik modul pada materi sistem pernapasan dikembangkan sesuai prosedur pengembangan Borg dan Gall yang dimodifikasi menjadi sembilan tahapan, dengan menggunakan sintaks model pembelajaran <em>guided discovery</em> yang bermuatan indikator-indikator kemampuan berpikir kritis yang divisualisasikan pada tujuan, materi, kegiatan, dan soal evaluasi modul; 2) kelayakan modul dinilai berkualifikasi sangat baik oleh penilaian ahli materi dengan pemenuhan 95,00%; ahli pengembangan modul 93,26%; ahli perangkat pembelajaran 90,57; dan ahli keterbacaan 96,88; rata-rata penilaian praktisi 98,29%; serta rata-rata penilaian siswa 88,11%; 3) Modul berbasis <em>guided discovery</em> efektif meningkatkan kemampuan berpikir kritis, didasarkan pada hasil uji <em>Independent Samples T Test </em>menunjukkan adanya perbedaan hasil <em>post-test</em> antara kelas yang menggunakan modul berbasis <em>guided discovery</em> dengan kelas yang menggunakan modul sekolah diperoleh sig 0,009 &lt; 0,05, serta peningkatan rata-rata <em>N-gain</em> sebesar 0,77 yang termasuk kualifikasi tinggi.
KAJIAN PRESTASI BELAJAR BIOLOGI MENGGUNAKAN MODEL SETS (SCIENCE, ENVIRONMENT, TECHNOLOGY, AND SOCIETY) DENGAN METODE OBSERVASI LABORATORIUM DAN METODE OBSERVASI LAPANGAN DI TINJAU DARI SIKAP ILMIAH DAN KREATIVITAS SISWA
Authors: Suranto Joko Dwi , Sajidan Sajidan , Suciati Suciati 
Published: July 2019

<p>Penelitian ini bertujuan untuk mengetahui pengaruh pembelajaran model SETS (<em>Science, Environment, Technology, and Society</em>) dengan metode observasi laboratorium dan metode observasi lapangan, sikap ilmiah dan kreativitas siswa serta interaksi ketiganya terhadap prestasi belajar siswa. Penelitian ini menggunakan metode eksperimen dan dilaksanakan Oktober 2011 sampai bulan Juni 2012. Populasi semua siswa kelas VII SMPN 2 Jatiroto, Wonogiri. Sampel penelitian diambil dengan metode <em>cluster random sampling </em>terdiri dari 2 kelas. Kelas VII A menggunakan model SETS dengan metode observasi laboratorium dan kelas VII B menggunakan model SETS dengan metode observasi lapangan. Data sikap ilmiah siswa dan kreativitas siswa sebagai variabel moderator diperoleh melalui angket, data prestasi belajar sebagai variabel terikat untuk aspek kognitif diperoleh melalui tes, dan data prestasi aspek afektif dan aspek psikomotor melalui lembar observasi. Analisis data menggunakan uji Anava desain faktorial 2x2x2 menggunakan<em> software </em>komputer<em> SPSS 17</em>. Hasil penelitian menunjukkan: (1) ada pengaruh prestasi belajar antara siswa yang diberi pembelajaran biologi model SETS dengan metode observasi laboratorium dan metode observasi lapangan; (2) ada pengaruh sikap ilmiah tinggi dan sikap ilmiah rendah terhadap prestasi belajar siswa; (3) ada pengaruh antara kreativitas tinggi dan kreativitas rendah terhadap prestasi belajar siswa; (4) tidak terdapat interaksi antara model SETS dengan metode observasi laboratorium dan metode observasi lapangan dengan sikap ilmiah terhadap prestasi belajar siswa; (5) tidak terdapat interaksi antara model SETS dengan metode observasi laboratorium dan metode observasi lapangan dengan kreativitas terhadap prestasi belajar siswa; (6) tidak terdapat interaksi antara sikap ilmiah dan kreativitas terhadap prestasi belajar siswa; (7) tidak terdapat interaksi antara metode observasi laboratorium dengan metode observasi lapangan, sikap ilmiah dan kreativitas terhadap prestasi belajar siswa.</p>
Evaluation of Clonal Uniformity in Six Superior Cacao Clones Based on SSR Marker
Authors: Sulistiyorini Indah , Rubiyo Rubiyo , Sudarsono Sudarsono 
Published: July 2019

<p><em>Propagation of cacao plants is generally carried out vegetatively. Therefore, plants that are clonally propagated should be genetically uniform. Genetic uniformity in cacao clones is also very important information for germplasm conservation and in obtaining pure parental crosses. Evaluation of genetic uniformity can be seen through analysis using SSR markers. This study aimed to determine the genetic uniformity in six cacao clones using SSR markers. This experiment was conducted at IIBCRI Integrated Laboratory in Sukabumi and Plant Molecular Biology Laboratory, IPB Bogor, from September 2015 to December 2016. Six cacao clones used (TSH 858, TSH 908, ICS 13, PA 300, GC 7 and UIT) are from Kalitelepak experimental station of PTPN XII, Genteng District, Banyuwangi, East Java. Ten samples were taken randomly to represent cacao clones. DNA amplification was carried out using 12 SSR markers. The result showed that 12 SSR markers generated 45 alleles with the number of alleles per locus was 3-4 alleles. The polymorphic information content (PIC) ranges from 0.37</em>–<em>0.67, which are identied as very informative molecular analysis </em><em>in identifying the genetical uniformity of the evaluated cacao population. Six SSR loci generated variant alleles within both the TSH 858 and UIT clones, indicating there are off-type plants in these two samples. Clonal uniformity were detected for samples of the GC 7, ICS 13, PA 300 and TSH 908 clones. On the other hand, 8.33% of evaluated samples within the TSH 858 and UIT clones were off-type plants.</em></p>
Relationship between performance on the progress test and selection for medical residency
Authors: Ferreira Ricardo Correa , Velho Paulo Eduardo Neves Ferreira , Bicudo Angélica Maria , Passeri Silvia Maria Riceto Ronchim 
Published: July 2019

Abstract
Background

The Progress Test (PT) is a formative evaluation used to analyze student progress throughout medical undergraduate studies. Further, classificatory summative assessments are carried out by medical graduates worldwide, either to acquire a practicing license or to obtain a vacancy in the Medical Residency (MR) selection processes. We aimed to identify whether performance in the PT is related to the performance in the MR selection process.

Methods

The physicians who attended and graduated from a public university in the state of São Paulo, Brazil, between 2011 and 2014 were assessed on the basis of voluntary participation in the PT throughout their undergraduate program, performance in the PT in their last year, performance in the multiple-choice test of the MR and convocation in the first classificatory list, and approval for the MR selection. Descriptive statistics and comparison of scores were performed using the Student t-test for independent and paired samples and the Pearson correlation coefficient.

Results

Of the 424 students, 374 had participated in the PTs throughout their undergraduate program and in the MR selection process. These graduates performed better in PT than the 22 who did not go on to MR (p < 0.05). The students who participated in all PT throughout their undergraduate program demonstrated superior performance in MR than those 22 who did not participate regularly (p < 0.0001). Among the 374 trainees, the average performance level for the PT was lower than that for the multiple-choice, both overall (p < 0.05) and separately by year (p < 0.0001); moreover, there was a strong correlation between PT performance and performance on the multiple-choice. There was greater approval in MR among graduates whose mean score on the multiple-choice test was above the mean score in PT (p < 0.0001).

Conclusions

PT performance was related to performance in the MR selection process for the study period; there was a strong correlation between student performance in the PT and multiple-choice test in MR. Students with multiple-choice test results for MR that were below the average performance level in the PT were less frequently approved in the MR selection process.
DETERMINANTS OF NEONATAL MORTALITY IN THE LARGEST INTERNATIONAL BORDER OF BRAZIL: A CASE CONTROL STUDY
Authors: de Souza Suzana , Duim Etienne Larissa , Nampo Fernando Kenji 
Published: July 2019

Abstract
BACKGROUND: Neonatal deaths correspond to 44% of the deaths in children under five globally. The most populous international border of Brazil includes Foz do Iguassu (Brazil), Puerto Iguazu (Argentina) and Ciudad del Este (Paraguay). Similarly to any other Brazilian city, the public health services located in Foz do Iguassu provide medical care to foreigners, including pregnant women who go to Brazil to deliver. Although the international importance of Foz do Iguassu in terms of healthcare, neonatal mortality in the city (15.3/1,000 live births) is higher than Brazil’s average (13.8/1,000 live births) and corresponds to 61% of all deaths in children under five. Unfortunately, the causes of the neonatal deaths in Foz do Iguassu remain unclear, which make it more difficult to manage the problem. The current study aimed to identify the determinants of neonatal mortality in Foz do Iguassu. METHODS: In this case-control study, we analyzed all neonatal deaths occurred in Foz do Iguassu from 2012 to 2016. Birth and mortality data were extracted from two national governmental databases (SINASC and SIM). We extracted data on (i) maternal sociodemographic characteristics, (ii) pregnancy care, and (iii) newborn characteristics. Multiple logistic regression with the conceptual framework was applied to examine the factors associated with neonatal mortality. RESULTS: Most of the deaths occurred in the early neonatal period (65.9%). The factors associated with neonatal death were fetal congenital anomaly (OR 22.4; CI 95% 7.41-67.76; p = <0.001); low birth weight (OR 17.4; CI 95% 8.70-35.17; p = <0.001), first minute Apgar score under 7 (OR 15.4; CI 95% 8.11- 29.24; p = <0.001); zero to 3 prenatal appointments (OR 3.3; CI 95% 1.28-8.70; p = 0.014) and prematurity (OR 3.5; CI 95% 1.79 6.92; p = <0.001). CONCLUSION: The high rate of neonatal death in Foz do Iguassu is strongly associated with newborn characteristics and not associated with maternal sociodemographic characteristics. Thus, the health services in the Brazilian side of this international borders should be aware of the quality of the prenatal care and childbirth attention provided.
Health problems and general anxiety among traffic police working in two major cities of Nepal
Authors: Thapa Subash , Ghimire Sargam , Aro Arja R 
Published: July 2019

Abstract
Objective

Traffic police are at-risk of various health problems due to an exposure to air pollution and high traffic; and traffic roads in some Nepalese cities are very congested. There is very little information about health problems of Nepalese traffic police. Therefore, a cross-sectional, self-administered questionnaire study among 252 traffic police was conducted to identify the common health problems and factors associated with different levels of general anxiety among traffic police working in two major cities of Nepal.

Results

Around 55% of traffic police had ear ringing problem, 57% had burning eyes, 64% had back pain, and 67% had breathing difficulties in the previous three months. Around 33% had moderate anxiety and 23% had persistent and severe anxiety. The multinomial logistic regression analysis showed that job dissatisfaction, ear ringing and eye irritation in the previous three months and having physical symptoms, namely eye irritation, ear ringing and back pain in last three months, were significantly associated with moderate anxiety. Further, age (25-30 years), gender (female), job dissatisfaction, and reporting ear ringing symptoms in the previous three months were significantly associated with severe anxiety.
REPEATED HIGH BLOOD PRESSURE AT 6 AND 11 YEARS AT THE PELOTAS 2004 BIRTH COHORT STUDY
Authors: Guttier Marilia Cruz , Barcelos Raquel Siqueira , Pereira Rodrigo Wiltgen , Bortolotto Caroline Cardozo , Dartora William , Schmidt Mari Inês , Matijasevich Alicia , Tovo-Rodrigues Luciana , Santos Iná S. 
Published: July 2019

Abstract
Background

We evaluated the prevalence and the factors associated with repeated high systolic (SBP) and diastolic blood pressure (DBP) at 6- and 11-year follow-ups of children from the Pelotas (Brazil) 2004 Birth Cohort.

Methods

All live births to mothers living in the urban area of Pelotas were enrolled in the cohort. Blood pressure (BP) values were transformed into Z-scores according to sex, age and height. High SBP and DBP were defined as repeated systolic and diastolic BP Z-scores on the ≥95th percentile at the two follow-ups. Prevalence (95% confidence interval) of repeated high SBP, DBP and both (SDBP) were calculated. Associations with maternal and child characteristics were explored in crude and adjusted logistic regression analyses.

Results

3182 cohort participants were analyzed. Prevalence of repeated high SBP, DBP and SDBP was 1.7% (1.2-2.1%), 2.3% (1.8-2.9%) and 1.2% (0.9-1.6%), respectively. Repeated high SBP was associated with male sex, gestational diabetes mellitus (2.92; 1.13-7.58) and obesity at 11 years (2.44; 1.29-4.59); while repeated high DBP was associated with female sex, family history of hypertension from both sides (3.95; 1.59-9.85) and gestational age <34 weeks (4.08; 1.52-10.96). Repeated high SDBP was not associated with any of the characteristcs investigated.

Conclusion

Prevalence of repeated high SBP, DBP and SDBP were within the expected distribution at the population level. Nonethless, gestational diabetes mellitus, obesity, family history of hypertension, and prematurity increased the risk of repeated high blood pressure measured at two occasions five years apart.
Using data on snus use in Sweden to compare different modelling approaches to estimate the population health impact of introducing a smoke-free tobacco product
Authors: Lee Peter , Djurdjevic Smilja , Pecze Laszlo , Weitkunat Rolf , Luedicke Frank , Fry John 
Published: July 2019

Abstract
Background

We have developed an approach for modelling the health impact of introducing new smoke-free tobacco products. We wished to compare its estimates with those of alternative approaches, when applied to snus, used in Sweden for many years.

Methods

Modelling was restricted to men aged 30-79 years for 1980-2009 and to four smoking-related diseases. Mortality data were extracted for Sweden and other European countries. Published data provided Swedish prevalence estimates for combinations of never/former/current smoking and snus use, and smoking prevalence estimates for other European countries. Approach 1 compares mortality in Sweden and in other countries with a smoking prevalence similar to Sweden’s prevalence of combined smoking/snus use. Approaches 2 and 3 compare mortality in Sweden with hypothetical mortality had snus users smoked. Approach 3 uses our health impact model, individuals starting with the tobacco prevalence of Sweden in 1980. Tobacco histories during 30-year follow-up were then estimated using transition probabilities, with risk derived using a negative exponential model. Approach 2 uses annual tobacco prevalence estimates coupled with estimates of relative risk of current and former smokers regardless of history. The main applications of Approaches 2 and 3 assume that only smoking affects mortality, though sensitivity analyses using Approach 3 allow for risk to vary in snus users and dual users.

Results

Using Approach 2, estimated mortality increases in Sweden in 1980-2009 had snus not been introduced were: lung cancer 8,786; COPD 1,781; IHD 10,409; stroke 1,720. The main Approach 3 estimates were similar (7,931; 1,969; 12,501; 1,901). They decreased as risk in snus users and dual users increased. Approach 1 estimates differed wildly (77,762; 32,538; 77,438; 76,946), remaining very different following correction for differences between Sweden and the comparison countries in non-smoking-related disease mortality.

Conclusions

Approach 1 is unreliable, accounting inadequately for non-tobacco factors affecting mortality. Approaches 2 and 3 provide reasonably similar approximate estimates of the mortality increase had snus not been available, but have differing advantages and disadvantages. Only Approach 3 considers tobacco history, but develops histories using tobacco transition probabilities, which is possibly less reliable than using estimated tobacco prevalences at each follow-up year.
A pair-wise meta-analysis highlights circular RNAs as potential biomarkers for colorectal cancer
Authors: Li Chen , He Xinli , Zhang Lele , Li Lanying , Zhao Wenzhao 
Published: July 2019

Abstract
Background: Circular RNAs (circRNAs) have emerged as a special subset of endogenous RNAs that are implicated in tumorigenesis and cancer progression. Herein we aim to carry out a meta-analysis to evaluate the clinicopathologic, diagnostic and prognostic significance of circRNA expression in colorectal cancer (CRC).
Methods: A systematic search of online databases was performed for original articles published in English, which investigated the diagnostic accuracy, prognostic utility, and clinicopathologic association of circRNA(s) in CRC. Data were strictly extracted and study bias was judged using the Quality Assessment for Studies of Diagnostic Accuracy II (QUADAS II) and Newcastle-Ottawa Scale (NOS) checklists.
Results: A total of 13 studies, involving 1430 patients with CRC, were included in the meta-analysis. The clinicopathologic study showed that abnormally expressed circRNAs were correlated with tumor diameter (P = 0.0350), differentiation (P = 0.0038), lymphatic metastasis (P = 0.0119), distant metastasis (P < 0.0001), TNM stage (P = 0.0002), and depth of invasion (P=0.001) in patients with CRC. The summary area under the curve (AUC) of circRNA for the discriminative efficacy between patients with and without CRC was estimated to be 0.79, corresponding to a weighted sensitivity of 0.77 [95% confidence interval (CI): 0.74-0.79], specificity of 0.67 (95%CI: 0.64-0.70), and diagnostic odds ratio (DOR) of 7.52 (95%CI: 4.66-12.12). Survival analysis showed that highly expressed circRNAs were correlated with significantly worse overall survival (OS) [hazard ratio (HR) = 2.66, 95%CI: 2.03-3.50, P = 0.000; X2 = 4.34, P = 0.740, I2 = 0.0%], whereas lower expression of circRNAs was associated with prolonged OS (weighted HR=0.30, 95%CI: 0.17-0.53, P = 0.000; X2 = 1.34, P = 0.909, I2 = 0.0%). Stratified analysis in circRNA expression status, and test matrix also showed robust results.
Conclusion: Abnormally expressed circRNAs may be auxiliary biomarkers facilitating CRC diagnosis, and promising prognostic biomarkers in predicting the survival of CRC patients.
Biosorption and enzymatic reduction of hexavalent chromium by chromium resistant bacteria ameliorate phytotoxicity
Authors: Hossan Shanewaz , Islam Mohammad Rafiqul , Kabir Mir Himayet , Ali Sobur , Islam Md Shafiqul , Imran Khan Mohammad , Mou Taslin Jahan , Parvez Anowar Khasru , Ahmed Niyaz , Mahmud Zahid Hayat 
Published: July 2019

Abstract
Background: Chromium (Cr) (VI) is one of the toxic heavy metals and environmental hazards. Alleviating the levels of contaminants in the environment is imperative, and studying the bioremediation of Cr via reduction or biosorption is an indispensable approach to this cause. In this study, we investigated the efficiency of reduction and biosorption of Cr(VI) by chromate resistant bacteria isolated from tannery wastewater.

Results: From screening, 28 Cr resistant bacteria were selected, and only two isolates, SH-1 and SH-2, were found as potential candidates for the reduction of Cr(VI). Post 16s rRNA sequencing, SH-1 isolate was identified to be Klebsiella sp and SH-2 isolate as Lysinibacillus sp. SH-1 could tolerate up to 2000 mg/L of Cr(VI) whereas, SH-2 could tolerate up to 1500 mg/L of Cr(VI). In Luria-Bertani media containing 100 mg/L of Cr(VI), the relative reduction level was 95% (SH-1) and 88.77% (SH-2) but their reduction rate was 63.08% (SH-1) and 49.89% (SH-2) of Cr(VI), respectively in the tannery effluents after 72h period of incubation. In the presence of Cr(VI) at a concentration of 10 mg/L Cr(VI), the cell-free extracts of pre-grown SH-1 and SH-2 showed a reduction of 72.2% and 33%, respectively. This reduction indicates the production or the activity of Cr reducing enzyme being higher in these two isolates than that of control in the presence of Cr(VI). In biosorption study, live and dead biomass of SH-1 biosorbed 51.25 mg and 29.03 mg chromium per gram dry weight, respectively. However, 28.83 mg and 27.65 mg chromium per gram dry weight were biosorbed by live and dead biomass of SH-2, respectively. Both the Langmuir model -for monolayer adsorption- and Freundlich model -for adsorption characteristics for the heterogeneous surface- were suitable for describing biosorption of Cr(VI) by SH-1 live biomass. The chickpea seed germination study confirmed the beneficial environmental effect of Cr(VI) reduction by these two isolates.

Conclusion: The bacterial isolates can be exploited for their potential for reduction and biosorption of toxic hexavalent chromium in biological treatment of hexavalent chromium-containing wastes.