bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study on the impact of data sampling rates on load signature event detection
Authors: Huchtkoetter Jana , Reinhardt Andreas 
Published: September 2019

Abstract
The analysis of electrical load signatures is an enabling technology for many applications, such as ambient assisted living or energy-saving recommendations. Through the digitalization of electricity metering infrastructure, meter reading intervals are gradually becoming more frequent than the traditional once-per-year reporting. In fact, across smart meter generations, samples were initially reported in 15-min intervals, more recently once per second, and even newer devices capture readings at rates on the order of several kilohertz. The advantages of using such high sampling rates have, however, not been unambiguously demonstrated in literature. We thus choose a widely considered application scenario of energy data analytics, event detection, and assess the impact of the sampling rate choice on the correct event recognition rate. More specifically, we compare the accuracy of two event detection algorithms with respect to the resolution of their input data. The results of our analysis hint at a non-linear relation between accuracy and data resolution, yet also indicate that most event occurrences can be correctly determined when using a sampling rate of approximately 1 kHz, with only minimal improvements achievable through higher rates.
Preoperative Delays in the Treatment of DCIS and the Associated Incidence of Invasive Breast Cancer
Authors: Ward William H. , DeMora Lyudmila , Handorf Elizabeth , Sigurdson Elin R. , Ross Eric A. , Daly John M. , Aggon Allison A. , Bleicher Richard J. 
Published: September 2019

Abstract

Background
Although treatment delays have been associated with survival impairment for invasive breast cancer, this has not been thoroughly investigated for ductal carcinoma in situ (DCIS). With trials underway to assess whether DCIS can remain unresected, this study was performed to determine whether longer times to surgery are associated with survival impairment or increased invasion.

Methods
A population-based study of prospectively collected national data derived from women with a clinical diagnosis of DCIS between 2004 and 2014 was conducted using the National Cancer Database. Overall survival (OS) and presence of invasion were assessed as functions of time by evaluating five intervals (≤ 30, 31–60, 61–90, 91–120, 121–365 days) between diagnosis and surgery. Subset analyses assessed those having pathologic DCIS versus invasive cancer on final pathology.

Results
Among 140,615 clinical DCIS patients, 123,947 had pathologic diagnosis of DCIS and 16,668 had invasive ductal carcinoma. For all patients, 5-year OS was 95.8% and unadjusted median delay from diagnosis to surgery was 38 days. With each delay interval increase, added relative risk of death was 7.4% (HR 1.07; 95% CI 1.05–1.10; P < 0.001). On final pathology, 5-year OS for noninvasive patients was 96.0% (95% CI 95.9–96.1%) versus 94.9% (95% CI 94.6–95.3%) for invasive patients. Increasing delay to surgery was an independent predictor of invasion (OR 1.13; 95% CI 1.11–1.15; P < 0.001).

Conclusions
Despite excellent OS for invasive and noninvasive cohorts, invasion was seen more frequently as delay increased. This suggests that DCIS trials evaluating nonoperative management, which represents infinite delay, require long term follow up to ensure outcomes are not compromised.
Can mammogram readers swiftly and effectively learn to interpret first post-contrast acquisition subtracted (FAST) MRI, a type of abbreviated breast MRI?: a single centre data-interpretation study
Authors: Jones Lyn I , Geach Rebecca , Harding Sam A , Foy Christopher , Taylor Victoria , Marshall Andrea , Taylor-Phillips Sian , Dunn Janet A 
Published: September 2019

Objectives:
To assess whether NHS breast screening programme (NHSBSP) mammogram readers could effectively interpret first post-contrast acquisition subtracted (FAST) MRI, for intended use in screening for breast cancer.

Methods:
Eight NHSBSP mammogram readers from a single centre (four who also read breast MRI (Group 1) and four who do not (Group 2)) were given structured FAST MRI reader training (median 4 h: 32 min). They then prospectively interpreted 125 FAST MRIs (250 breasts: 194 normal and 56 cancer) comprising a consecutive series of screening MRIs enriched with additional cancer cases from 2015, providing 2000 interpretations. Readers were blinded to other readers’ opinions and to clinical information. Categorisation followed the NHSBSP MRI reporting categorisation, with categories 4 and 5 considered indicative of cancer. Diagnostic accuracy (reference standard: histology or 2 years’ follow-up) and agreement between readers were determined.

Results:
The accuracy achieved by Group 2 (847/1000 (85%; 95% confidence interval (CI) 82–87%)) was 5% less than that of Group 1 (898/1000 (90%; 95% CI 88–92)). Good inter-reader agreement was seen between both Group 1 readers (κ = 0.66; 95% CI 0.61–0.71) and Group 2 readers (κ = 0.63; 95% CI 0.58–0.68). The median time taken to interpret each FAST MRI was Group 1: 34 s (range 3–351) and Group 2: 77 s (range 11–321).

Conclusion:
Brief structured training enabled multiprofessional mammogram readers to achieve similar accuracy at FAST MRI interpretation to consultant radiologists experienced at breast MRI interpretation.

Advances in knowledge:
FAST MRI could be feasible from a training-the-workforce perspective for screening within NHSBSP.
Activation of the leptin pathway by high expression of the long form of the leptin receptor (Ob-Rb) accelerates chondrocyte senescence in osteoarthritis
Authors: Zhao Xiang , Huang Ping , Li Gen , Lv Zhendong , Hu Guangyu , Xu Qingrong 
Published: September 2019

Objectives Activation of the leptin pathway is closely correlated with human knee cartilage degeneration. However, the role of the long form of the leptin receptor (Ob-Rb) in cartilage degeneration needs further study. The aim of this study was to determine the effect of increasing the expression of Ob-Rb on chondrocytes using a lentiviral vector containing Ob-Rb. Methods The medial and lateral cartilage samples of the tibial plateau from 12 osteoarthritis (OA) patients were collected. Ob-Rb messenger RNA (mRNA) was detected in these samples. The Ob-Rb-overexpressing chondrocytes and controls were treated with different doses of leptin for two days. The activation of the p53/p21 pathway and the number of senescence-associated β-galactosidase (SA-β-gal)-positive cells were evaluated. The mammalian target of rapamycin (mTOR) signalling pathway and autophagy were detected after the chondrocytes were treated with a high dose of leptin. Results In total, 12 cases were found to have severe medial cartilage wear compared with the lateral cartilage. Immunofluorescence showed that the expression of Ob-Rb in the medial cartilage of the tibial plateau was high. High levels of leptin led to cell cycle arrest and inhibited autophagy. After overexpression of Ob-Rb, the physiological dose of leptin induced cell senescence in the chondrocytes. High doses of leptin inhibited autophagy by activating the mTOR signalling pathway. Blockade of the mTOR signalling pathway could restore autophagy and partially reverse senescence induced by leptin in chondrocytes. Conclusion In summary, the present study demonstrated that high doses of leptin induce cell senescence by activating the mTOR pathway in chondrocytes from OA cartilage. Highly expressed Ob-Rb accelerates chondrocyte senescence by activating the leptin pathway in OA. Cite this article: X. Zhao, P. Huang, G. Li, L. Zhendong, G. Hu, Q. Xu. Activation of the leptin pathway by high expression of the long form of the leptin receptor (Ob-Rb) accelerates chondrocyte senescence in osteoarthritis. Bone Joint Res 2019;8:425–436. DOI: 10.1302/2046-3758.89.BJR-2018-0325.R2.
Clement of Alexandria
Authors: Kovacs Judith L. 
Published: September 2019

Abstract
Dieser Beitrag untersucht das originäre Denken Klemens von Alexandriens (ca. 150 - ca. 215), eines frühen Interpreten der gesamten Bibel und Wegbereiter der philosophischen Interpretation des Evangeliums. Er behandelt zunächst Klemens Leben, Werk und Kontext in Alexandria und betrachtet anschließend seine Antworten auf die folgenden Fragen: (1) Was ist der Sinn des menschlichen Lebens? (2) Wer ist Gott und wie kann er erkannt werden? (3) Was ist Gottes Gesamtplan für die Erlösung des Menschen? (4) Wie soll der Christ zur Vollkommenheit und ewigen Betrachtung Gottes vorankommen? Klemens war ein optimistischer und aufgeschlossener Wahrheitssuchender in einer Zeit, in der die christliche Religion gerade erst Gestalt annahm. Er war der Ansicht, dass die Erkenntnis Gottes und die Liebe zu ihm der Grund des Seins des menschlichen Lebens sei und dass Gottes Heilsplan ein komplexes System der Erziehung und Vollkommenheit beinhalte. Dieser schließe auch Christus, das göttlichen Wort, den ultimativen Lehrer, ein. Seine biblische Exegese und Theologie hinterließen ein wichtiges Vermächtnis bei späteren Theologen, insbesondere im griechischsprachigen Osten.
Basilius von Cäsarea (329?–378?) in der Polyphonie der Kirchenväter
Authors: Zachhuber Johannes 
Published: September 2019

Abstract
The article offers a brief presentation of Basil of Caesarea (329-378) in the context of a polyphony of the church fathers. Basil, one of the most influential figures in the entire history of the Eastern Church, held close contacts with many other major theologians and bishops of his time. His large corpus of extant letters gives a strong sense of his participation in a polyphonic interaction between diverse Christian voices. Yet he is also elusive and often difficult to integrate into conventional categories of patristic history. This can be explained by his pragmatic approach to theology which uniquely combines deep intellectual sophistication with a level-headed awareness of the practical needs of the Church in his own time.
Juventude e magreza
Authors: Neiva Renata Maria de Oliveira 
Published: September 2019

RESUMO
É proibido ser gorda. Não se envelhece mais. A beleza se constrói. Como um dos maiores jornais brasileiros do século XX contribuiu para a educação do corpo feminino. Pelas páginas do Correio da Manhã, as mulheres encontraram, recorrentemente, duas prescrições: antipeso e antienvelhecimento.
PALAVRAS-CHAVE:Imprensa. Mulheres. Educação.

ABSTRACT
Women are not allowed to be fat. There is no more aging. Beauty is built. The way one of the greatest Brazilian newspapers of the twentieth century contributed to the education of the female body. In the pages of the newspaper Correio da Manhãwomen have, repeatedly, found two prescriptions: anti-weight gain and anti-aging.
KEYWORDS: Press. Women. Education.
Experiências femininas na carreira da docência superior: entre o cotidiano da “casa” e da profissão
Authors: Furlin Neiva 
Published: September 2019

Este artigo analisa narrativas de mulheres (casadas e freiras) que atuam na docência superior em teologia católica, e pretende evidenciar como elas circulam entre a profissão e os trabalhos domésticos, naturalizados como femininos.
PALAVRAS-CHAVE: Divisão sexual do trabalho. Docência superior. Desigualdade de gênero. Profissão..

ABSTRACT
This article analyzes narratives of women (married and nuns) who teach Catholic theology at a college level and aims to show how they circulate between their profession and housework, culturally considered women’s work.
KEYWORDS: Sexual division of labor. Higher education teaching. Gender inequality. Profession
Deusa e/ou bruxa? Uma análise dos dizeres sobre o feminino ontem e hoje
Authors: Daróz Elaine Pereira , Garcia Dantielli Assumpção , Abrahão e Sousa Lucília Maria 
Published: September 2019

Filiados à Análise de Discurso (Pêcheux), propomos uma análise dos dizeres sobre a mulher presentes no romance português A dama pé de cabra, que se atualizam nos jornais jornalístico (online), para compreendermos o lugar dessa memória sobre a mulher na esfera social.
PALAVRAS-CHAVE: Análise de Discurso. Mídia. Mulher. Memória.

ABSTRACT
In the light of the theoretical assumptions of Discourse Analysis (Pêcheux), we propose an analysis of the discourses about women, present on the Portuguese novel The lady of the goat, and updated in online journalistic discourse, in order to understanding of the imaginary about women on the social sphere.
KEYWORDS: Discourse Analysis. Media. Woman. Memory.
PENGEMBANGAN HOMESTAY BERBASIS MASYARAKAT PADA KAMPUNG HOMESTAY BOROBUDUR
Authors: Wedatama Abid Affandi , Mardiansjah Fadjar Hari 
Published: September 2019

Candi Borobudur merupakan destinasi wisata yang termasuk ke dalam Situs Warisan Dunia UNESCO pada tahun 1991 yang memberikan potensi pengembangan aktivitas ekonomi serta pariwisata. Masyarakat Dusun Ngaran 2 Desa Borobudur memanfaatkan potensi pariwisata dengan melakukan pengembangan homestay berupa Kampung Homestay Borobudur yang hingga saat ini mencapai 27 homestay dengan melibatkan elemen masyarakat dan para pengelola homestay Dusun Ngaran 2. Penelitian ini menggunakan metode kualitatif dan pendekatan eksploratif untuk menjelaskan proses pengembangan homestay serta analisis triangulasi dan penarikan kesimpulan untuk mengetahui peran masyarakat dan teknologi informasi di dalamnya. Pengembangan homestay yang berbasis pada masyarakat ini melibatkan dua aspek kegiatan yaitu peningkatan mutu pelayanan dan penyedia kegiatan pariwisata. Selain itu, terdapat juga peran teknologi informasi yang digunakan untuk sistem pemesanan yang terkomputerisasi pada media booking.com atau melalui situs yang dibangun khusus oleh pengurus homestay pada www.kampunghomestayborobudur.com sebagai bagian dari pengembangan aktivitas pariwisata, ekonomi dan teknologi untuk menciptakan pariwisata yang berkelanjutan.
PERAN STAKEHOLDER DALAM PENGELOLAAN WISATA PANTAI DI KELURAHAN AIR MANIS, KECAMATAN PADANG SELATAN
Authors: Gustina Rizky Dwi , Mussadun Mussadun 
Published: September 2019

Pantai Air Manis merupakan salah satu wisata yang sedang dikembangkan oleh pengelola wisata, Dinas Kebudayaan dan Pariwisata Kota Padang. Kondisi dan ketersediaan atraksi maupun fasilitas wisata yang tersedia masih kurang. Penelitian ini bertujuan untuk mengetahui peran stakeholder dalam pengelolaan wisata Pantai Air Manis. Penelitian dilakukan dengan metode deskriptif kualitatif. Data diperoleh melalui wawancara, observasi, dan telaah dokumen. Hasil dari penelitian menunjukkan bahwa terdapat dua kategori stakeholder yang terlibat dalam pengelolaan wisata yaitu Dinas Kebudayaan dan Pariwisata, Dinas PU, dan Dishub sebagai stakeholder kunci dan masyarakat lokal sebagai stakeholder primer. Stakeholder kunci berperan sebagai koordinator dan fasilitator dalam mengelola atraksi, akomodasi, aksesibilitas serta informasi dan promosi wisata. stakeholder primer berperan sebagai fasilitator dan pelaksana dalam atraksi, akomodasi serta aksesibilitas wisata. Disbudpar memiliki kapasitas yang rendah karena belum mampu mengcover pengelolaan wisata. Oleh karena itu wisata dicover oleh masyarakat lokal sehingga menyebabkan kondisi atraksi serta fasilitas wisata kurang baik dan kurang terawat.
Feature fusion to increase the robustness of machine learners in industrial environments
Authors: Holst Christoph-Alexander , Lohweg Volker 
Published: September 2019

Abstract
Industrial applications put special demands on machine learning algorithms. Noisy data, outliers, and sensor faults present an immense challenge for learners. A considerable part of machine learning research focuses on the selection of relevant, non-redundant features. This contribution details an approach to group and fuse redundant features prior to learning and classification. Features are grouped relying on a correlation-based redundancy measure. The fusion of features is guided by determining the majority observation based on possibility distributions. Furthermore, this paper studies the effects of feature fusion on the robustness and performance of classification with a focus on industrial applications. The approach is statistically evaluated on public datasets in comparison to classification on selected features only.
Mechanomyography-based assessment during repetitive sit-to-stand and stand-to-sit in two incomplete spinal cord-injured individuals
Authors: Abd Aziz Musfirah , Hamzaid Nur Azah , Hasnan Nazirah , Dzulkifli Muhammad Afiq 
Published: September 2019

AbstractStanding up and sitting down movements are important prerequisites to achieve functional independence in everyday life of spinal cord injury (SCI) patients. Thus, mechanomyography (MMG) was proposed as a safe monitoring tool to evaluate muscle function performance of these activities. Two incomplete SCI participants performed repetitive sit-to-stand (SitTS) and stand-to-sit (StandTS) until fatigued challenge. Three sets of these activities were completed with MMG sensors attached over the quadriceps muscles of both legs. A 5-min rest was allocated between each set, totalling 399 trials of SitTS and StandTS activities. There was a significant difference between MMG’s mean root mean square maximum (RMSmax) in SitTS and StandTS activities (p = 0.014). The mean values of RMSmax and root mean square average (RMSave) on the right leg were detected to be significantly higher compared to those of the left leg during these activities (p < 0.05). In the frequency domain, MMG’s mean power frequency (MPF) proved to be significantly higher at the beginning compared to the end of the three sets of both activities (p = 0.000). These muscle performances during both activities can be verified based on the analysis of MMG behaviour in time and frequency domains. Furthermore, this study indicated that MMG can be used as a monitoring tool to identify muscle fatigue throughout a prolonged event.
The haptic and perceptional characteristics of an anthropomorphic curved soft finger structure
Authors: Yuvaraj S. , Malayalamurthi R. , Raja K. Venkatesh 
Published: September 2019

Abstract
In recent decades, modeling of soft fingertips has fascinated a superior momentum in research initiatives concerned with development of an anthropomorphic soft finger tip. In design and development of soft fingertips, analysis of contact a characteristic plays a vital role on dexterous manipulation. This research work presents the results of the experimental investigation in relation to the formulations of contact area for soft fingertips pressed against assorted target profiles. A dimensionless parameter, curve factor Y (r/R) is introduced to derive a parametric relationship among the key parameters. It also addresses the growth of contact area of fingertips for five different combinations. From experimental observations, a modified power law equation with conversion factor (X) is proposed to interpolate the magnitude of contact area for different profiles.
Change in Distillation Column Control Philosophy Using Dynamic Simulation
Authors: Parmar Kanubhai , Dash Sukanta , Patil Sunil , Padmavathi Garimella 
Published: September 2019

AbstractAt condensate stripper of a cracker plant with design control philosophy for composition control pant was facing operational difficulty. Due to disturbance in operating parameter column was becoming unstable and product was getting offspec w.r.t. desired purity. One of the applications of dynamic simulation is to troubleshoot the challenges related to control philosophy in practical application. Since steady-state simulation models cannot predict behavior with respect to time, initially steady state model and finally a dynamic model was developed in Aspen HYSYS. The model is used to study the process behavior for existing control philosophy and proposed philosophy. To avoid column puncture and without waiting for plant shut down the existing Temperature Indicator (TI) considered as Temperature Indicator Controller (TIC) for the study. A new control philosophy was developed based on the response of variables after disturbances in feed rate and composition. The revised control philosophy has been implemented and is now working satisfactorily, providing stabilized operation of the column with consistent bottom product quality. This has helped to reduce the loss of C2s in the bottom stream by about 700 ppm, for savings of about $100,000 USD per year.
Experience, Its Edges, and Beyond
Authors: Davey Nicholas 
Published: September 2019

Abstract
This essay offers a reflection on the notion of experience considered within the context of framework of relational ontology. The primary advantage of such a consideration is that it escapes the consequences of subject-object accounts of experience, accounts which either laud the cognitive subject as master of the experienced world or exile it to an existence in a world it does not experience as its own. Setting experience within a relational ontology and developing a participatory epistemology around the concept offers an inter-active account of experience as an ontological process and an integrated account of knowing and being. This ends the traditional privileging the human as a cognitive subject and opens the way to thinking of all elements within interactive processes as interpretive agencies. Furthermore, it allows the category of interpretation to be freed from the domain of cognitive subjects and to become a descriptor of ontological interaction in general.
Qualität im Kontext der Integrierten Versorgung
Authors: Mayer Peter J. 
Published: September 2019

Zusammenfassung
Gewachsene Strukturen bilden die Ausgangslage, Integrierte Gesundheitsversorgung das Ziel. Jede verantwortungsvolle Unternehmerin und jeder verantwortungsvolle Unternehmer hätte den Fokus längst auf die individuellen Versorgungsbedarfe und Bedürfnisse seiner Klientinnen und Klienten gelegt und sämtliche Prozesse bedarfs- und bedürfnisgerecht ausgerichtet. Strukturen haben nur den einen Zweck, die Prozesse bestmöglich zu unterstützen. Für die Gesundheitsversorgung bedeutet dies: Auf allen Ebenen des Gesundheitssystems den Mut aufzubringen, sich ausschließlich an Krankheitsbildern und Versorgungsbedürfnissen zu orientieren, – im Sinne einer gelebten Kultur der Versorgungsqualität.
MDK-Qualitätskontroll-Richtlinie – Instrument zur Qualitätssicherung im Krankenhaus
Authors: Haun Oliver 
Published: September 2019

Zusammenfassung
Bisher werden Qualitätsvorgaben, welche anhand von Richtlinien des G-BA erlassen werden, auf Grundlage des § 275 Abs. 4 SGB V durch den MDK geprüft. Die Beauftragung durch die Krankenkassen sowie die nachgelagerte Prüfpraxis gestalten sich je nach Bundesland dabei sehr heterogen. Mit dem Krankenhausstrukturgesetz (KHSG) wurde deshalb Anfang 2016 eine Grundlage geschaffen, um mit der MDK-Qualitätskontroll-Richtlinie nach § 275a SGB V ein systematisches Prüfgeschehen und eine transparente Qualitätssicherung zu gewährleisten.
Measurement of L X-ray production cross sections and relative intensities of some lanthanide compounds depending on the temperature
Authors: Cinan Esra , Aygün Bünyamin , Sayyed M. I. , Özdemir Yüksel 
Published: September 2019

Abstract
L X-ray intensity ratios for CeO2, Sm2(SO4)3, Ho2O3, and Yb2O3 compounds were experimentally investigated. The measurements were gauged following excitation by 59.54 keV γ-rays from a 100 mCi 241Am radioactive annular source at different temperatures in situ. Temperature change occurred between 50 °C and 400 °C. L X-ray emission spectra were obtained by using a solid-state Si(Li) X-ray detector. L X-ray production cross sections, intensity ratios, and full-width half maximum (FWHM) values for the compounds were determined by evaluating the emission spectra varying with the temperature. According to the results obtained, it was observed that L
β1 X-rays were less influenced in comparison with Lα X-rays while Lα X-rays were also less influenced in comparison with Lβ
2 X-rays.