bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gestão Pública Educacional: A Importância da Afetividade no Processo Educativo Infantil / Public Educational Management: The Importance of Affectivity in the Children's Educational Process
Authors: Alencar Cláudio , Floriano Auriélia Coelho Isaque , Eugênio Aparecida Vieira Souza , Teles Inalda Maria De Sá Carvalho 
Published: March 2019

A Educação Infantil é uma das fases do desenvolvimento humano que requer mais atenção e dedicação, tanto nos aspectos intelectual, emocional, social como motor da criança. O Objetivo do presente estudo foi discutir a importância da afetividade no desenvolvimento da criança, baseando-se sobre as concepções de Piaget, Wallon e Vygotsky acerca do desenvolvimento cognitivo e da afetividade. Concluiu-se que a escola deve valorizar a criança e compreende-la em sua totalidade. Há uma indissociabilidade entre educar e cuidar, que deve ser valorizada, para que seja possível perceber a relação entre cognição e afetividade.
Seroprevalence and geographical distribution of hepatitis C virus in Iranian patients with thalassemia: a systematic review and meta-analysis
Authors: Shamshirian Amir , Alizadeh-Navaei Reza , Pourfathollah Ali Akbar , Alipoor Reza , Mohseni Ali Reza 
Published: March 2019

AbstractBackgroundThalassemia as a hereditary hemoglobinopathy is the most common monogenic disease worldwide. Patients with thalassemia require regular blood transfusion, which provides the risk for the transmission of hepatitis C virus (HCV) as the most common post-transfusion infection in such patients, and this rate is very diverse in different parts of the world. We aimed to determine the prevalence of HCV among patients with thalassemia in Iran.MethodsIn this study, we searched for articles on the prevalence of HCV among Iranian thalassemia patients in English and Persian databases up to 2017. Heterogeneities were assessed by using anI-square (I2) test. Prevalence and 95% confidence interval (CI) were calculated using the random effects model.ResultsIn total, 37 studies with 9185 patients were included in the meta-analysis. The prevalence of HCV among Iranian thalassemia patients was 17.0% (95% CI: 14.5–19.8). The rate of prevalence among male and female subjects was 17.4% (95% CI: 13.8–21.9) and 16.8% (95% CI: 13.2–21.1), respectively.ConclusionsWe found that the prevalence of HCV among Iranian thalassemia patients declined over time and the Iranian Blood Transfusion Organization has had a reasonable performance in HCV screening.
Optimized Inventory Control on Construction Materials by Application of E-Technology Transfer along JIT
Authors: Harsha Vardhana Balaji , Venugopal Pulidindi 
Published: March 2019

Abstract
Most of the construction projects in India experience ineffective inventory control because of the application of the conventional method. This conventional procurement management method is commonly practiced (more than 95 % of the time), which encourages improper utilization of resources in construction industries. Material procurement is a financially operated arena that requires technology transfer rather than common techniques. Construction stakeholders are generally unaware of E-Technology development. Recent E-Technology commerce networking and communication has been drastically improved and thus can be effectively utilized to produce uninterrupted supply chain management in construction procurement systems; additionally, this technological transfer system in construction industries can improve the profit margins and can avoid time overrun of construction projects.
A Human TRPA1-Specific Pain Model
Authors: Heber Stefan , Gold-Binder Markus , Ciotu Cosmin I. , Witek Martin , Ninidze Nino , Kress Hans-Georg , Fischer Michael J.M. 
Published: March 2019

The cation channel transient receptor potential ankyrin 1 (TRPA1) plays an important role in sensing potentially hazardous substances. However, TRPA1 species differences are substantial and limit translational research. TRPA1 agonists tested previously in humans also have other targets. Therefore, the sensation generated by isolated TRPA1 activation in humans is unknown. The availability of 2-chloro-N-(4-(4-methoxyphenyl)thiazol-2-yl)-N-(3-methoxypropyl)-acetamide (JT010), a potent and specific TRPA1 agonist, allowed us to explore this issue. To corroborate the specificity of JT010, it was investigated whether the TRPA1 antagonist (1E,3E)-1-(4-fluorophenyl)-2-methyl-1-penten-3-one oxime (A-967079) abolishes JT010-elicited pain. Sixteen healthy volunteers of both sexes rated pain due to intraepidermal injections of different concentrations and combinations of the substances. The study design was a double-blind crossover study. All subjects received all types of injections, including a placebo without substances. Injections of the TRPA1 agonist dose-dependently caused pain with a half-maximal effective concentration of 0.31 μm. Coinjection of A-967079 dose-dependently reduced and at a high concentration abolished JT010-induced pain. Quantification of JT010 by HPLC showed that a substantial part is adsorbed when in contact with polypropylene surfaces, but that this was overcome by handling in glass vials and injection using glass syringes. Isolated TRPA1 activation in humans causes pain. Thus, intradermal JT010 injection can serve as a tool to validate new TRPA1 antagonists concerning target engagement. More importantly, TRPA1-specific tools allow quantification of the TRPA1-dependent component in physiology and pathophysiology.SIGNIFICANCE STATEMENTThis study showed that activation of the ion channel transient receptor potential ankyrin 1 (TRPA1) alone indeed suffices to elicit pain in humans, independent of other receptors previously found to be involved in pain generation. The newly established TRPA1-specific pain model allows different applications. First, it can be tested whether diseases are associated with compromised or exaggerated TRPA1-dependent painful sensations in the skin. Second, it can be investigated whether a new, possibly systemically applied drug directed against TRPA1 engages its target in humans. Further, the general possibility of quantitative inhibition of TRPA1 allows identification of the TRPA1-dependent disease component, given that the substance reaches its target. This contributes to a better understanding of pathophysiology, can lay the basis for new therapeutic approaches, and can bridge the gap between preclinical research and clinical trials.
Obecność cudownego wizerunku Matki Bożej Łaskawej ze Lwowa w Tarnowie i wątki tarnowskie w biografii abp. Eugeniusza Baziaka
Authors: Soprych Jacek 
Published: March 2019

Liczne związki abp. Eugeniusza Baziaka z Tarnowem, szczególnie jego zaufanie do pasterza diecezji bp. Jana Stepy, pozwoliły na złożenie w depozycie dwóch najcenniejszych skarbów metropolii lwowskiej – srebrnej trumienki z relikwiami bł. Jakuba Strzemię oraz obrazu Matki Bożej Łaskawej. Wizerunek Matki Bożej z lwowskiej katedry łacińskiej jest dla Polaków szczególną narodową pamiątką. To przed nim 1 kwietnia 1656 roku król Jan Kazimierz ślubował bronić wiary katolickiej i praw ludu, a Maryję obrał Królową Korony Polskiej. Po drugiej wojnie światowej zmieniły się granice naszej ojczyzny i Lwów pozostał poza nią. Arcybiskup Baziak wywiózł tę ważną relikwię do Polski. Nie mógł zostawić tak wielkiego skarbu. Nie mógł narażać go na profanację czy zniszczenie. Tarnów stał się ważnym przystankiem, gdzie przez wiele lat ukrywany był ten cenny wizerunek.
Charakterystyczne cechy egzegezy Pisma Świętego św. Tomasza z Akwinu
Authors: Michalik Andrzej 
Published: March 2019

Święty Tomasz z Akwinu był nie tylko znakomitym filozofem i teologiem, ale także niestrudzonym egzegetą Pisma Świętego. Spod jego pióra wyszły komentarze zarówno do ksiąg Starego, jak i Nowego Testamentu. Egzegeza św. Tomasza z Akwinu odznacza się kilkoma cechami. Jest to egzegeza oparta na dwóch fundamentalnych regułach: analogii wiary katolickiej i analogii wiary biblijnej. Ponadto posiada także charakterystyczny dla całej egzegezy średniowiecznej rys scholastyczny, patrystyczny i teologiczny.
Szczególnie zasłużeni dla nauki i kultury. Doktorzy honoris causa Uniwersytetu Papieskiego Jana Pawła II w Krakowie w latach 2015–2018
Authors: Stala Józef 
Published: March 2019

Doktor honoris causa jest stopniem akademickim przyznawanym komuś, kto miał szczególny wkład w rozwój określonej dyscypliny, społeczeństwa lub Kościoła. W latach 2015–2018 doktorat honoris causa Uniwersytetu Papieskiego Jana Pawła II w Krakowie otrzymali: Profesor Elie Wiesel – 30 czerwca 2015, Papież Benedykt XVI – 3 lipca 2015, Arcybiskup Celestino Migliore – 16 października 2015, Ksiądz Professor Michał Heller – 22 czerwca 2016, Kardynał Profesor Gerhard Ludwig Müller – 16 października 2017, Profesor Rémi Brague – 11 stycznia 2018. W niniejszym artykule są przedstawione wszystkie osoby docenione przez Uniwersytet Papieski Jana Pawła II w Krakowie za wysiłki na rzecz pokojowego rozwiązywania konfliktów na całym świecie poprzez promowanie międzywyznaniowego dialogu, zrozumienie, wnikliwą inteligencję oraz ich znaczący wkład na rzecz Kościoła.
Biyodizel Yan Ürünü Olan Gliserolden Üretilen Katalizör ile Yakıt Katkı Maddesi Bütil Levulinat Sentezi
Authors: ÜNLÜ Derya 
Published: March 2019

Biyodizelin yan ürünü olarak gliserol üretiminin
fazlalığı gliserolün değerlendirilmesi için araştırmacıları yeni ürün
arayışlarına itmiştir. Bu çalışmada biyo-türevli gliserol, tek bir adımda karbonizasyon
ve sülfonasyon yoluyla heterojen katı asit katalizör sentezi için bir karbon başlatıcısı
olarak kullanılmıştır. Üretilen katalizör,
yakıt biyokatkı maddesi bütil levulinat sentezlemek üzere levulinik asit
ile bütanolün esterleşme reaksiyonunu katalizlemek için kullanılmıştır. Katalizör
karakterizasyonu; FTIR, TGA ve XRD cihazları kullanılarak yapılmıştır.
Katalizörün katalitik aktivitesini belirlemek için deneyler farklı reaksiyon sıcaklıklarında,
farklı molar besleme oranlarında ve farklı katalizör yükleme oranlarında
kesikli reaktörde gerçekleştirilmiştir. En yüksek dönüşüm değeri 70oC’de,
molar besleme oranı (alkol/asit) 9:1 kullanılarak ve %7 katalizör yükleme
oranında altı saatin sonunda %96.25 olarak elde edilmiştir. Katalizör esterleşme
reaksiyonunun polar ortamından zarar görmemektedir. Bu nedenle, katalitik aktivitesini
kaybetmeden sekiz kez tekrar kullanılmıştır.
The Lipide-Soluble Vitamin Contents Of Some Lathyrus Species
Authors: BAHŞİ Muammer , EMRE İrfan , GENÇ Hasan , ŞAHİN Ahmet , YILMAZ Ökkeş 
Published: March 2019

In
the present study, lipide-soluble vitamin contents in the seeds of the Lathyrus L. taxa (Lathyrus sylvestris L., Lathyrus
sphaericus Retz.; Lathyrus pratensis L.,
L. aphaca L. var. modestus P.H., L. aphaca L. var. biflorus
Post., L. aphaca var. pseudoaphaca (Boiss.) P.H. Davis, Lathyrus odoratus L., Lathyrus hierosolymitanus Boiss., Lathyrus tauricola P.H. Davis) were
determined by using HPLC. Data obtained from present study showed that studied Lathyrus taxa have high beta-caroten
content (146,5±1,73-375,0±3,35 µg/g).
present study found that Lathyrus
pratensis has the higesht
gamma-tocopherol content (158,9±3,65 µg/g) whilst L.
aphaca var. pseudoaphaca (Boiss.)
P.H. Davis has highest D3 vitamin content (43,2±2,18 µg/g) among studied taxa. However, it was found that the
r-tocopherol, a-tocopherol, a-tocopherol acetate, retinol, retinol acetate, D2
and K1 vitamins of studied Lathyrus taxa
were lowest.
Autonomía profesional versus la práctica basada en la obediencia
Authors: Lopera Betancur Martha Adiela , Paiva Duque Luis Eduardo , Forero Pulido Constanza 
Published: March 2019

Estudio realizado con enfermeras que laboran en una IPS de tercer nivel. Medellín 2015- 2016.
comprender el significados que las enfermeras le dan a la autonomia
Elaboración de cupones en acero de bajo carbono, mediante proceso de soldadura por arco eléctrico con electrodo manual revestido, con defectos inducidos e inspeccionados por métodos visuales y tintas penetrantes
Authors: Duque Díaz Óscar Iván , Benítez Bohórquez Ángel René 
Published: March 2019

La soldadura es una técnica de unión de componentes metálicos, la cual se ha convertido en uno de los procedimientos más utilizados en la conformación de partes o elementos utilizados en la fabricación de estructuras, ductos, máquinas, equipos y en general accesorios con los cuales se puede mejorar ostensiblemente la calidad de vida del hombre. La generación por soldadura de una unión resistente, duradera que garantiza un alto grado de seguridad, ofreciendo un buen acabado del conjunto, realizada a bajos costos, además de ofrecer una amplia variedad de factores de producción, han hecho que los procesos de soldadura tomen una posición relevante en la calidad de la industria metalmecánica.
A fin de cumplir con las exigencias a las que cada día se ve sometida la industria, es necesario formar soldadores capacitados con competencias laborales que les permitan llegar a ser certificados y participar en procesos eficientes en términos de calidad y competitividad.
Como aporte a esta necesidad de formación, este proyecto tiene como objetivo desarrollar un material didáctico, mediante el cual se presenta un diseño apropiado de una junta soldada junto con las variables de proceso, demostrando su soldabilidad; partiendo de estos parámetros se han modificado las condiciones en la intensidad de corriente aportada para inducir defectos en cupones soldados en platina de acero de bajo carbono, mediante proceso de soldadura por arco eléctrico con electrodo revestido (SMAW).
Se busca así, proporcionar información técnica y orientación a los aprendices e instructores de los programas de formación en “soldadura de platina con el proceso de arco eléctrico con electrodo revestido (SMAW)” desarrollados en el SENA Centro Industrial y de Desarrollo Industrial de Soacha; con ello estimular la reflexión del aprendiz sobre la planificación en la elaboración de proyectos de soldadura y proporcionar las fuentes que puedan motivar esta reflexión y como introducir mejoras en su propio proceso de formación y apropiación de nuevas tecnologías.
EVALUATION OF THE MITOCHONDRIA RESPIROMETRIC FUNCTION IN THE CONDITIONS OF PATHOLOGIES OF VARIOUS GENESES
Authors: Voronkov A. V. , Pozdnyakov D. I. , Nigaryan S. A. , Khouri E. I. , Miroshnichenko K. A. , Sosnovskaya A. V. , Olokhova E. A. 
Published: March 2019

The aim of the paper is to assess the change in the mitochondrial respirometric function under conditions of various pathologies.Materials and methods. The study was performed on male Wistar rats. Experimental focal cerebral ischemia, traumatic brain injury, coronary occlusive myocardial infarction and muscle dysfunction were used as pathological models. Focal ischemia was reproduced by the method of irreversible thermocoagulation of the middle cerebral artery. Traumatic brain injury was modeled by the method of free fall of the load. Experimental myocardial infarction was reproduced by ligating the descending branch of the left coronary artery. Muscle dysfunction was modeled by the method of «forced swimming with a 20% burden». The respiratory function of mitochondria was assessed by the method of respirometry by the change in oxygen consumption when introducing mitochondrial respiration into the medium: Oligomycin, Rotenone and FCCP. Additionally, we evaluated the intensity of the glycolysis process and the activity of respiratory complexes I, II, IV and V. In order to comprehensively assess the respiratory function, an ELISA study was conducted to determine the concentration of ATP, mitochondrial ATP synthetase, cytochrome C oxidase and NADP-Oxidase 4.Results. In the course of the study it was established that under conditions of experimental cerebral ischemia, traumatic brain injury, myocardial infarction and muscle dysfunction, the ATP-generating ability of mitochondria the maximum breathing and respiratory capacity deteriorated, herby the decrease in overall respiratory function was accompanied by an increase in glycolysis, which was uncompensated, as well as dysfunction of mitochondrial complexes I, II, IV and V, confirmed by an increase in NADPH oxidase 4 activity and a decrease in cytochrome C oxidases and ATP synthetase. As a result, the observed changes in mitochondrial respiration function contributed to a decrease in ATP concentration under conditions of cerebral ischemia - by 3.2 times (p <0.05), traumatic brain injury – by 2.6 times (p <0.05), myocardial infarction – by 1.8 times (p <0.05) and muscle dysfunction – by 4 times (p <0.05).Conclusion. Basing on the data obtained, we can assume that in conditions of cerebral ischemia, traumatic brain injury, myocardial infarction and muscle dysfunction, there is deterioration of the mitochondrial respirometric function with inhibition of ATP synthesis and increased glycolysis.
STIMULATION OF REPARATION IN A LINEAR WOUND MODEL IN RATS BY BISCHOFIT GEL
Authors: Stepenko Yu. V. , Soldatov V. O. , Zatolokina M. A. , Mayorova A. V. , Sysuev B. B. , Demidenko A. N. , Ivahno E. N. , Sarycheva M. V. , Pokrovskiy M. V. 
Published: March 2019

The aim of the article is to evaluate Bischofit gel reparative activity in a linear wound model in rats.Materials and Methods. The study was conducted on 36 male Wistar rats weighing from 193 to 218 grams. On the 8th day after modeling a linear wound defect 50±1 mm long, the reparative effect of bischofite, Actovegin and Contractubex in the gel compositions was evaluated. The evaluation was carried out using: the following methods: 1) studying the physicomechanical characteristics of the wound defect (a wound-tearing machine Metrotest REM-0.2-1); 2) morphological examination of the skin graft taken from the wound area (stained with hematoxylin-eosin and Van Gieson‘s solution); 3) determining the ratio of collagen types I and III in a polarizing microscope (the picrosirius was red); 4) cоlorimetric analysis of the hydroxyproline concentration in the wound surface tissues.Results. On the 8th day, the wound defects sampled from the bischofite treated animals, were characterized by the most pronounced strength (the average force at the rupture moment was 13.70 N), which was significantly higher (p<0.01) than in the control group (11.76 N). Actovegin showed less influence on this parameter (12.60 N), and the use of Contractubex led to its decrease (8.10 N). The effect of the drugs on the morphological state of the skin tissue was similar. The hydroxyproline concentration in the studied groups’ samples was: Bischofit 13.23±1.68; Actovegin 15.89±1.37; Contractubex 17.61 ± 0.67; the Control was 16.59±1.08. According to the impact on the ratio of collagen in types I and III, the studied drugs were arranged in the following sequence: Bishofit (0.73±0.023) > Actovegin (0.67±0.017) > Control (0.56±0.012) > Contractubex (0.38 ±0.020).Conclusion. The carried out study showed that Bischofit has a pronounced ability to stimulate the regeneration of the skin wound defect. Hereby, the reference drug Actovegin showed less activity, and Contractubex worsened wound healing.
Factor Affecting Corporate Social Responsibility Within Global Reporting Initiatives
Authors: Gunawan Martin 
Published: March 2019

<p class="Body">Many studies describe the Corporate Social Responsibility Disclosure (CSRD) that emerged since 2007 as obligation and deduction of earnings and requires listed companies to perform philantrophy as part of legitimacy act. This research conducted to determines the hypothesis factors of CSRD specified to Global Reporting Initiavites (GRI) standards in 2014 and 2015 that implemented framework GRI G4. The qualitative and quantitative findings using regression analysis test, best equation model, classic assumption test for 22 sustainability reporting showed current ratio, debt to equity, size, institutional ownership and age have significant effects. This research show increasing disclosure and the recurring topics of standardized CSRD from among members of GRI group. </p>
Single-Tier or Dual-Tier Tax Systems: Implication for Petroleum Project Economics in Nigeria
Authors: Echendu Joseph C. , Idowu Adekunle J. , Adejumo Adedapo , Iledare Omowunmi O. , Akinlawon Adeyemi J. 
Published: March 2019

Summary
In this work we evaluate the effects of the single-tier tax system (STS) at its current rate in comparison to the proposed dual-tier tax system (DTS) in the National Petroleum Fiscal Policy in Nigeria on project economic performance. We also expound on the arguments between two schools of thought (single tax and dual tax proponents) toward understanding the rationale underlying the divergent viewpoints. The methodological approach applies the discounted cash flow modeling framework to evaluate the performances of terrain-based projects using selected metrics, such as internal rate of return, discounted payout, net present value, and government take (GT) under the two tax systems. This approach calibrates the unit technical cost for typical deepwater projects in Nigeria and imposes the current and proposed fiscal terms. Varying cost treatment options and alternative allowables//incentives are investigated in the modeling framework using global best practices.
We conclude that whichever tax system is adopted, it is possible to achieve equivalent economic metrics. However, the DTS presents a better, more flexible option over the STS because one of the split rates—especially the hydrocarbon resource tax—could serve as an instrument to incentivize investment, promote conservation, and expand the resource base through technology innovation more easily without denying the mineral owner an outright revenue through taxation. In a classical case such as Nigeria, in which the national fiscal budget is largely financed using hydrocarbon revenue, the DTS seemingly offers a better option for revenue sharing among the stakeholders—the resource owners and the Federal Government—than the current single upstream tax system. Our discussion in this paper bridges the gap between the divergent viewpoints on the taxation system in Nigeria by proffering a pathway. We suggest that the overall objectives of stakeholders could be achieved using either STS or DTS metrics if the mechanics in designing the fiscal system is better understood. This will lead to progressive application in achieving divergent expectations.
Detection of potentially pathogenic enteric viruses in environmental samples from Kenya using the bag-mediated filtration system
Authors: van Zyl Walda B. , Zhou Nicolette A. , Wolfaardt Marianne , Matsapola Peter N. , Ngwana Fhatuwani B. , Symonds Erin M. , Fagnant-Sperati Christine S. , Shirai Jeffry H. , Kossik Alexandra L. , Beck Nicola K. , Komen Evans , Mwangi Benlick , Nyangao James , Boyle David S. , Borus Peter , Taylor Maureen B. , Scott Meschke J. 
Published: March 2019

Abstract
Enteric virus environmental surveillance via a highly sensitive method is critical, as many enteric viruses have low infectious doses and can persist in the environment for extended periods. This study determined the potential of the novel bag-mediated filtration system (BMFS) to recover human enteric viruses and pepper mild mottle virus (PMMoV) from wastewater and wastewater-impacted surface waters, examined PMMoV use as a fecal contamination indicator in Kenya, and identified potential BMFS process controls. From April 2015 to April 2016, BMFS samples were collected from seven sites in Kenya (n = 59). Enteroviruses and PMMoV were detected in 100% of samples, and human adenovirus, human astrovirus, hepatitis A virus, norovirus GI, norovirus GII, sapovirus, and human rotavirus were detected in the majority of samples. The consistent detection of enteroviruses and PMMoV suggests that these viruses could be used as indicators in similarly fecally contaminated sites and BMFS process controls. As contamination of surface water sources remains a global issue, enteric virus environmental surveillance is necessary. This study demonstrates an effective way to sample large volumes of wastewater and wastewater-impacted surface waters for the detection of multiple enteric viruses simultaneously.