bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of prednisolone administration on gallbladder emptying rate and gallbladder bile composition in dogs
Authors: Nagahara Takuro , Ohno Koichi , Kanemoto Hideyuki , Kakimoto Toshiaki , Fukushima Kenjiro , Goto-Koshino Yuko , Tsujimoto Hajime 
Published: September 2018

Abstract
OBJECTIVE To investigate effects of prednisolone administration on gallbladder emptying rate and gallbladder bile composition in dogs.
ANIMALS 6 healthy Beagles.
PROCEDURES Prednisolone was administered (2 mg/kg, SC, once daily for 2 weeks) to each dog and tapered over 2 weeks. Gallbladder emptying rate and bile composition were evaluated before and after administration of prednisolone for 2 weeks as well as 1 week after cessation of prednisolone administration.
RESULTS Gallbladder emptying rate decreased significantly after prednisolone administration (median, 27%; range, 0% to 38%), compared with rate before administration (median, 59%; range, 29% to 68%), but then increased 1 week after cessation of administration (median, 45%; range, 23% to 48%). Gallbladder bile mucin concentration decreased significantly after prednisolone administration (median, 8.8 mg/dL; range, 6.2 to 11.3 mg/dL), compared with concentration before administration (median, 13.1 mg/dL; range, 10.7 to 21.7 mg/dL), but then increased 1 week after cessation of administration (median, 14.3 mg/dL; range, 9.6 to 26.7 mg/dL). Gallbladder taurochenodeoxycholic acid concentration decreased significantly after prednisolone administration (8.1 mmol/L; range, 6.8 to 15.2 mmol/L), compared with concentration before administration (median, 27.2 mmol/L; range, 22.0 to 31.9 mmol/L), but then increased 1 week after cessation of administration (median, 26.4 mmol/L; range, 15.1 to 31.5 mmol/L).
CONCLUSIONS AND CLINICAL RELEVANCE A lower gallbladder emptying rate caused by prednisolone administration may be involved in the pathogenesis of gallbladder disease in dogs. Further studies are required to determine the clinical importance of lower gallbladder bile mucin concentrations caused by glucocorticoid administration in the pathogenesis of gallbladder disease in dogs.
Pharmacokinetics and pharmacodynamics of mycophenolic acid in healthy cats after twice-daily intravenous infusion of mycophenolate mofetil for three days
Authors: Slovak Jennifer E. , Rivera-Velez Sol M. , Hwang Julianne K. , Villarino Nicolas F. 
Published: September 2018

Abstract
OBJECTIVE To evaluate the plasma disposition of mycophenolic acid (MPA) and its derivatives MPA glucuronide and MPA glucoside after twice-daily infusions of mycophenolate mofetil (MMF) in healthy cats for 3 days and to assess the effect of MMF administration on peripheral blood mononuclear cell (PBMC) counts and CD4+-to-CD8+ ratios.
ANIMALS 5 healthy adult cats.
PROCEDURES MMF was administered to each cat (10 mg/kg, IV, q 12 h for 3 days). Each dose of MMF was diluted with 5% dextrose in water and then administered over a 2-hour period with a syringe pump. Blood samples were collected for analysis. A chromatographic method was used to quantitate concentrations of MPA and its metabolites. Effects of MMF on PBMC counts and CD4+-to-CD8+ ratios were assessed by use of flow cytometry.
RESULTS All cats biotransformed MMF into MPA. The MPA area under the plasma concentration–time curve from 0 to 14 hours ranged from 14.6 to 37.6 mg·h/L and from 14.4 to 22.3 mg·h/L after the first and last infusion, respectively. Total number of PBMCs was reduced in 4 of 5 cats (mean ± SD reduction, 25.9 ± 15.8% and 26.7 ± 19.3%) at 24 and 48 hours after the end of the first infusion of MMF, respectively.
CONCLUSIONS AND CLINICAL RELEVANCE Plasma disposition of MPA after twice-daily IV infusions for 3 days was variable in all cats. There were no remarkable changes in PBMC counts and CD4+-to-CD8+ ratios.
Histopathological Diagnostic Criteria for Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features Highlighted by Six Illustrative Cases
Authors: Nechifor-Boilă Adela , Dee Edit , Borda Angela 
Published: September 2018

Abstract
Introduction. The encapsulated, non-invasive subtype of follicular variant of papillary thyroid carcinoma (FVPTC) represents approximately 10% to 20% of all thyroid cancers. Many studies over the past decade have shown that these tumors carry an indolent clinical course, with no recurrence, even in patients treated by lobectomy. Their reclassification as neoplasms with “very low malignant potential” has recently been suggested by an international group of experts and a new terminology was proposed: “non-invasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTP). However, a diagnosis of NIFTP is still challenging for many pathologists in daily practice. Presentation of case series. By presenting six illustrative cases of NIFTP, this article aims to highlight the diagnostic criteria and the burden difficulties when dealing with NIFTP cases. Characteristic histological features, inclusion and exclusion criteria for NIFTP, as well as sampling guidelines and differential diagnosis challenges are all discussed. Conclusions. The diagnosis of NIFTP is not straightforward and requires meeting strict inclusion and exclusion criteria. Total sampling of the tumor capsule in these cases is mandatory in order to exclude invasion (capsular and/or vascular). A diagnosis of NIFTP promotes a less-aggressive patient management that is, no need for completion thyroidectomy or radioactive iodine therapy.
Glomus Tumor of the Kidney: Case report
Authors: Dee Edith , Loghin Andrada , Toth Tamas , Năznean Adrian , Borda Angela 
Published: September 2018

Abstract
Introduction: Glomus tumors are rare benign mesenchymal neoplasms accounting for only 2% of all types of soft tissue tumors. Commonly located in the peripheral soft tissues, they are most frequently encountered in the subungual areas of fingers and toes, and very rarely in visceral organs due to the absence of glomus bodies. To date, 22 cases of primary renal glomus tumors have been described in the literature, of which 17 benign, with no evidence of recurrence or metastasis, three cases of malignant glomus tumor, and two cases with uncertain malignant potential. Case report: We report the 18th case of a benign glomus tumor of the kidney in a 49-year-old female patient, presenting the microscopic appearance (round, uniform cells with indistinct borders, scant finely granular eosinophilic cytoplasm, round nuclei lacking prominent nucleoli, arranged in solid sheets, accompanied by slit-like vascular spaces), the immunohistochemical profile (tumor cells showed immunoreactivity for smooth muscle actin, vimentin, as well as for CD34; they were negative for AE1/AE3, desmin, HMB-45, S-100 protein, renin, and chromogranin), and the differential diagnosis of this rare entity (juxtaglomerular tumor, angiomyolipoma, hemangioma, epithelioid leyomioma, solitary fibrous tumor, carcinoid tumor, and paraganglioma). Conclusion: Primary renal glomus tumors are rare tumors that radiologically can mimic other mesenchymal renal neoplasm. Accurate diagnosis is based on the microscopic appearance and especially the characteristic immunophenotype.
Impact of a One Day Crisis Resource Management Training on the Work Satisfaction among Emergency Department Healthcare Staff
Authors: Truta Teodora Sorana , Ban Irina , Boeriu Cristian , Petrisor Marius , Moldovan Diana Aniela , Copotoiu Sanda Maria 
Published: September 2018

Abstract
Objective: To evaluate the impact of a single day Crisis Resource Management (CRM) oriented team training, combining didactic and simulation sessions, on work satisfaction of the healthcare staff working in an Emergency Department. Methods: Seventy health professionals with different qualifications, working in an emergency department, were enrolled in the study. After enrollment, participants were asked to complete a work satisfaction questionnaire and to choose a day for the training session according to their availability. Each training session took place in the simulation center and consisted of several elements: didactic session and simulation session, followed by instructor facilitated debriefing. The lecture was focused on medical errors and CRM principles. Two months after, they were asked to complete again the work satisfaction questionnaire. Results: There were no significant improvements on the items evaluated through the work satisfaction questionnaire for none of the professional categories involved, except for ‘the possibility to refer the patient to a specialist whenever was considered necessary’ for the doctors. Improvements were seen for the same professional category on the following items: workload, leisure time, level of stress at work, time and energy spent on administrative tasks. Conclusions: The findings of this study do not support the effectiveness of a single day CRM training as a tool to improve the work satisfaction among medical staff in ED. Further research is necessary.
Theoretical Investigation of Pressure Distribution in a Multi-Typal Transport Unit
Authors: Nalobina Olena , Muravunets Yulia , Gerasimchuk Alexander , Puts Vitaly , Shovkomyd Alexander 
Published: September 2018

Abstract
This article presents the results from the theoretical research of tension loading in a channel of fixing conveyor of the apparatus for flax beating and scutching. The analyses of literature have shown that the quality of flax fibre greatly depends on the conditions of retted straw processing by means of breaking-scutching machines, namely on machine parameters, operating regimes and design characteristics. There are considerable high fibre losses due to inappropriate fixing of straw in the conveyor canal; percentage of these losses is much higher than losses caused by any other reasons. The paper presents equations for calculation of pressure inside the conveyor canal of apparatus for flax breaking and scutching. It investigates the regularities of pressure loading in the sectors which fix the straw according to the aforementioned equation. Research shows that the highest pressure occurs in the area opposite the press-rolls axis; it decreases when distancing from it. Research also shows that pressure in the axis zone is lower when the belt tension and spring compression are low. This pressure loading causes pulling of the strands from the conveyor canal and fibre losses. These theoretical regularities can be utilized for calculation of the fixation force to secure the retted straw between belts in order to reduce the losses.
Applications of Shallow Seismic Refraction Measurements in the Western Carpathians (Slovakia): Case Studies
Authors: Brixová Bibiana , Mosná Andrea , Putiška René 
Published: September 2018

Abstract
Shallow seismic measurement, specifically seismic refraction tomography, is an effective geophysical method that has applications in various sectors. It enables the search for and determination of the course of the interfaces, thus helping to resolve geological, environmental, hydrogeological, engineering, geotechnical and other problems. The paper demonstrates the possibilities of using these methods through examples of shallow seismic measurements that have been performed at various four locations in the Western Carpathian Mountains. The first case study describes Monastery Pond at Katarínka. It was found that, the basement of the Monastery pond is at a depth of 2-3 m below the surface and the results were also confirmed by electrical resistivity tomography (ERT). The next measurement through the thermal power station waste storage showed that the storage area base runs at a depth of about 20 m under the measured profile. The third case study addresses the depth of groundwater depth in the area of Borská nízina. The measurement confirmed the assumed depth of ground water level at 3.35 m below the surface. In the last case study, border fault between the Turiec Basin and the Malá Fatra Mts. was mapped by application of shallow refraction methods. The results show that shallow seismic methods shed light on the problem and in combination with other geophysical methods are an effective tool with great potential. They provide very useful data for shallow mapping applications.
Enhancement of the free residual chlorine concentration at the ends of the water supply network: Case study of Souk Ahras city – Algeria
Authors: Bensoltane Mohamed A. , Zeghadnia Lotfi , Djemili Lakhdar , Gheid Abdalhak , Djebbar Yassine 
Published: September 2018

AbstractThe drinking-water supply sector has mostly targeted the water-borne transmission of pathogens. The most common method employed is the chlorination of drinking-water at treatment plants and in the distribution systems. In Algeria, the use of chlorine in drinking water treatment is a widespread practice. To enhance the concentration of the residual chlorine in the public water-supply system of a part of Souk Ahras city (Faubourg) (Algeria) known by its low concentration of the free residual chlorine (according to the water utility – Algérienne des Eaux: ADE investigation) especially at the point of use, practical steps were carried out. The method is a combination between numerical simulation using EPANET2 software and field measurements. Using statistical analysis the hydraulic model was calibrated and the observed values were very closer to the simulated results. The concentration was improved throughout the network after the injection of the appropriate dose.
Analysis of effective factors on agricultural water management in Iran
Authors: Feizabadi Yaser , Gorji Effat Masomi 
Published: September 2018

AbstractThe aim of this study was to analyse the factors affecting agricultural water management in Iran based on irrigation experts’ point of view using factor analysis approach. The results indicated that conservation of modern irrigation equipment, promoting farmers’ knowledge, creating a watercourse (surface water collection), imposing a ban on digging new wells and educating the effectiveness of pressurized irrigation system were all known as the most important factors affecting agricultural water management. Moreover, factor analysis results showed that five factors influencing agricultural water management (institutional and legislative, educational and promotional, economic, technical and farming system) explained 64.29% of the total variance. At the end, some policy suggestions were provided in order to improve agricultural water management in Iran.
Assessment of metallic contamination in sediment and mullet fish (Mugil cephalus Linnaeus, 1758) tissues from the East Algerian coast
Authors: Ouali Naouel , Belabed Bourhane E. , Zeghdoudi Fadila , Rachedi Mounira 
Published: September 2018

AbstractThe present work was designed to assess the contamination level in the coastal of Annaba, following the spectrophotometric determination of the level of some metallic elements (Fe, Cu, Pb, Zn, Ni and Cd) in the sediments along an increasing bathymetric gradient (10 m and 20 m), as well as in the biological indicator grey mullet (Mugil cephalus) muscle. During the winter period (2014), 12 surface sediment samples, and a total of 24 fish were collected. Once the samples are dried, crushed and sieved, 0.5 g dry weight of each sample was added to concentrated acids. The results showed that the levels of some metals are superior to the recommended guideline values, and consequently the sediment of this bay is contaminated by iron, lead and copper. The contamination index (CI) showed a general tendency in the concentration of the studied metals as follows: Fe > Pb > Cu > Zn > Ni > Cd, since the most studied metals occurred at higher concentration in depth (20 m).However, the average concentrations of metals in fishes were found to be as the following order: Fe > Zn > Pb > Cu > Ni > Cd. The consumption of fish from some contaminated sites can be dangerous because concentrations of lead, cadmium and zinc exceed the international standards. Moreover, the strong positive correlation observed between the metallic elements of sediments and fishes confirm that these metals resulted from the similar sources of the anthropic activities, such as domestic, port, industrial and agricultural waste discharges. This is confirmed by the determined of pollution load index (PLI) parameter. Conclusively, a regular monitoring program of heavy metal is recommended for protecting these organisms, and to reduce the environmental risks.
Active Zone of Permanent Magnet Synchronous Machine with a Non-Overlapping Concentrated Winding
Authors: Orlova S. , Pugachov V. , Otankis R. 
Published: September 2018

Abstract
The research is devoted to the investigation of NdFeB permanent magnet (PM) based synchronous generators with non-overlapping concentrated windings. The rotor of such a generator has 10 pole pairs (PMs), which is dictated by the nominal voltage frequency (f=50 Hz) and the rotational speed (n=300 RPM). Comparison is made for four generators with three-phase winding coils and stator tooth numbers 18, 21, 24 and 27.
Re-Use and Recycling of Different Electrical Machines
Authors: Rassõlkin A. , Kallaste A. , Orlova S. , Gevorkov L. , Vaimann T. , Belahcen A. 
Published: September 2018

Abstract
The paper discusses the current developments in the recycling of electrical machines. The main attention is devoted to three types of motors: synchronous reluctance motor, permanent magnet assisted synchronous reluctance motor, and induction motor. Base materials of such electrical machines are also described in the paper. Rare-earth permanent magnets used in electrical machines are review separately. Moreover, the paper considers the features of the disassembly and recycling options.
Consideration of Solution for Enhancement of Frequency Converter Supply Power Parameters
Authors: Rankis I. , Zaleskis G. 
Published: September 2018

Abstract
The paper presents results of analysis of a possible solution for enhancement of frequency converter (FC) AC supply power parameters. The method proposed is based on switched stabilisation of DC current of FC front-end rectifier unit. Such stabilisation allows obtaining rather good AC supply power parameters, i.e., its power factor and total harmonics distortion (THD) indicator for phase current. The paper also demonstrates a possible realisation scheme, a simplified mathematical description of processes in the scheme, as well as methods for consideration of its parameters, accounting the rated power of FC and the appointed level of the rectifier DC current continuity ratio. The results of computer simulation, to a great extent, testify a possible enhancement level.
Water Demineralization by Membrane Distillation Utilizing Cooling Water From Municipal Waste Incinerator
Authors: Gryta Marek 
Published: September 2018

Abstract
The membrane distillation performance was studied for production of demineralized water from surface water (river). Hot water from cooling water system of municipal waste incinerator was considered as an energy source for membrane distillation. The integration of membrane installation with such cooling water system allows to re-use up to 18 kW per 1 m2 of the membranes. The studies were performed with the application of polypropylene capillary membranes Accurel PP S6/2. The membrane modules were supplied with the feed heated to a temperature of 310 K and 330 K. The permeate fl ux obtained for these temperatures was 2.8 and 9.7 L/m2 h, and the distillate conductivity was 6 and 4 S/cm, respectively. The water demineralisation process was carried out for 1200 h without module cleaning. The behaviour of the permeate fl ux and distillate conductivity indicate that used membranes maintained their non-wettability over tested period. The performed SEM-EDS examinations confi rmed, that the deposits did not fi ll the pores and were mainly formed on the membrane surface. The scaling intensity was defi nitely smaller for lower temperature (310 K) of the feed. The amorphous deposits containing beside Ca also substantial amounts of the Si were mainly formed under these conditions, whereas at higher feed temperature dominated CaCO3 scaling.
PENDEKATAN REGRESI SPLINE UNTUK MEMODELKAN POLA PERTUMBUHAN BERAT BADAN BALITA
Authors: SUKERNI NI LUH , SUKARSA I KOMANG GDE , SUCIPTAWATI NI LUH PUTU 
Published: September 2018

The study is aimed to estimate the best spline regression model for toddler’s weight growth patterns. Spline is one of the nonparametric regression estimation method which has a high flexibility and is able to handle data that change in particular subintervals so thus resulting in model which fitted the data. This study uses data of toddler’s weight growth at Posyandu Mekar Sari, Desa Suwug, Kabupaten Buleleng. The best spline regression model is chosen based on the minimum Generalized Cross Validation (GCV) value. The study shows that the best spline regression model for the data is quadratic spline regression model with six optimal knot points. The minimum GCV value is 0,900683471925 with the determination coefficient equals to 0,954609.
METABOLIC AND PATHOPHYSIOLOGICAL DISORDERS IN HUMAN ORGANISM DURING PROLONGED STARVATION
Authors: Khoroshinina L. P. , Churilov L. P. 
Published: September 2018

Relevance.The number of starving people throughout the world as well as global financial costs related to the development of alimentary-dependent conditions and diseases constantly increase. Intention. To review the scientific literature on the problems of metabolic and pathophysiological disorders caused by longterm starvation in human organism.Methodology.The available domestic and foreign sources of scientific information were studied.Results and Discussion.Paper describes the data on the pathogenesis of prolonged famine, on the endo- and exogenous causes of starvation, on qualitative and quantitative types of starvation, as well as the changes in metabolism of various organs and systems in completely starving organism during all periods of complete starvation (that of emergency, long-term adaptation, and decompensation) with their detailed endocrine-metabolic features. The results of the main research works by the Leningrad physicians who lived and worked in besieged Leningrad during the Great Patriotic War are recalled.Conclusion.The information presented is important for biomedical science and health practice as well, since emergencies can be associated with prolonged starvation of people in the modern world.
ARTHROSCOPIC LATARJET PROCEDURE: TECHNIQUE-RELATED CHARACTERISTICS, MID-TERM FUNCTIONAL RESULTS
Authors: Gudz Yu. V. , Vetoshkin A. A. , Chebotarev S. V. 
Published: September 2018

Relevance.Post-traumatic shoulder instability is widespread in the population and has a high social significance. Low efficacy of shoulder instability treatment determined the development of more than 300 surgical methods.Intention.The objective of the work is to study mid-term functional results of arthroscopic Latarjet surgery for treatment of shoulder instability with significant defects in the anterior edge of the scapula articular process and the humeral head.Methodology.68 arthroscopic Latarjet surgeries were performed over the period of 2013–2017 in the clinic No.2, Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (St. Petersburg). There were analyzed the duration of surgery, the position of the coracoid process graft relative to the glenoid, functional evaluation of the treatment results.Results.The average duration of a surgery was (91 ± 12) minutes. The time for the procedure reduced with the acquisition of skills. The graft was placed in the correct position (in the range of 02.30–05.30 o’clock of the imaginary dial) in 88% of cases. Only one episode of recurrent shoulder dislocation occurred in 9 months. The limitation of external shoulder rotation averaged to 7° (from 5 to 14°).Conclusion.Mid-term clinical results of arthroscopic Latarjet surgery have confirmed that the procedure can be reliable and safe for performance as well as functionally advantageous.