bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aromaticity‐Dependent Memristive Switching
Authors: Cechosz Ewelina , Alluhaibi Lulu , Mazur Tomasz , Sławek Andrzej , Pandurangan Nanjan , Szaciłowski Konrad 
Published: November 2024

AbstractIn recent years, memristors have drawn attention as non‐volatile memory devices for advanced computing engineering. The features of memristors, such as hysteresis, high resistance state to low resistance state ratio, retention time, etc., are determined by the material, structure of the device, the switching mechanism, and the kinetics resulting from the characteristics of the materials. Here, a resistive switching is proposed based on the aromaticity change of the material. A device has been built based on tetracyclone that undergoes the transition from an antiaromatic to an aromatic state upon applied potential. This phenomenon results in the presence of two distinguishable, and more importantly, stable resistive states of the memristor. On the basis of theoretical and experimental investigation, it is demonstrated that the working principle of the device depends on the redox change of the molecules. This study provides the foundation for a new kind of memristive switching mechanism: the formation of virtual conductivity paths. They can be a key to improving the performance of semiconductor memory devices in crucial factors such as stability, reversibility, and nonvolatility because these paths are related to electron delocalization and do not involve any significant structural changes in the device (e.g., diffusion).
Route Planning Process by the Endangered Black Lion Tamarin in Different Environmental Contexts
Authors: Bufalo Felipe , Kaisin Olivier , de Almeida e Silva Anne‐Sophie , Amaral Rodrigo Gonçalves , Messaoudi Yness , Alcolea Mirela , Zanette Eduardo M. , Sabino Gabriel Pavan , Börger Luca , Culot Laurence 
Published: November 2024

ABSTRACTDaily, primates take a variety of decisions to establish why, when, and where to move. However, little is known about the factors influencing and shaping primate daily routes. We investigated the decision‐making processes linked to route planning in four groups of black lion tamarins (BLT—Leontopithecus chrysopygus). We studied these endangered platyrrhines within four distinct environmental contexts across their natural distribution (i.e., a continuous forest, a 500‐ha forest fragment, a 100‐ha forest fragment, and a riparian forest). We used the Change Point Test to identify the points of significant direction change (CPs), which can be considered travel goals along BLT daily trajectories and are key components of travel planning. Considering the high importance of fruits and gum in BLT's diet, we predicted that feeding trees would be the main factor shaping their paths (feeding CPs‐FCPs). Also, given previous evidence that platyrrhines use landmarks (i.e., characteristic features from the terrain) as nodes in route network systems (i.e., points of intersection connecting habitual route segments), we expected part of CPs to be located close to the intersection points and to be associated with “locomotion” behavior (LCPs). Analyzing 61 daily paths in four forest fragments, our results showed that BLTs planned routes to reach feeding trees, which primarily determined path orientation. As hypothesized, locomotion was the most frequent behavior observed in CPs, but only in the continuous and riparian forests, with LCPs located as close to intersections as FCPs. Interestingly, these two areas presented the most extreme values (i.e., higher and lower values, respectively) in terms of used area, richness of resources and distances traveled between fruit‐feeding trees. Our results suggest that BLTs plan daily routes conditional on the environmental context to reach travel goals, likely to maximize route efficiency to reach out of sight feeding trees.
Fundamental research on phase equilibrium concerning hydrogen storage process with liquid organic hydrogen carriers
Authors: Shi Qinchuan , Wang Shiyuan , Li Peiya , Lu Shuhan , Wang Bo , Wang Jiahui , Wang Bin , Yang Fusheng , Fang Tao 
Published: November 2024

AbstractLiquid organic hydrogen carrier (LOHC) technology stands as a pivotal solution to the challenges of hydrogen storage and transportation. However, the efficiency of its hydrogenation process has yet to meet the stringent requirements for practical applications. Consequently, an in‐depth understanding of hydrogen equilibrium concentration determination within LOHCs is crucial for optimizing the hydrogenation process. This work leverages the PE 2000 software to simulate literature data on the solubility of hydrogen in LOHCs, yielding comprehensive phase equilibrium data for hydrogen across various LOHCs. Cubic equations of state along with diverse mixing rules were employed to correlate the phase equilibrium data, calculating the corresponding binary interaction parameters and generating phase diagrams accordingly. The simulation outcomes were meticulously discussed to identify the optimal thermodynamic model for each system. Ultimately, a rational simulation methodology was established that accurately correlates experiment data of H2 and LOHCs, offering a valuable reference for future studies in this domain.
Decoding the acidity effect of Pt‐based dehydrogenation catalysts on their dehydrogenation performance
Authors: Zhang Haijuan , Piao Xilin , Mingming Zhao , Haotian Chi , Mingyuan Lou , Yuan Gao , Chang Yuanhao 
Published: November 2024

AbstractPropane dehydrogenation (PDH) has become a significant method for propylene production. However, the systematic effects of catalyst acidity on dehydrogenation performance remain unclear. In this study, Pt‐based dehydrogenation catalysts with different acidities were prepared using n‐nonane modification, and their dehydrogenation performance was evaluated and compared. The synergistic interactions between the catalyst's acidity and its metallic functionality were thoroughly investigated. The results demonstrate that the relationship between the acidity of the PDH catalyst, the selectivity for propylene, and catalyst coke deposition follows a volcano‐shaped curve. An optimal acidity exists that allows Pt‐based dehydrogenation catalysts to achieve efficient performance. Specifically, the desorption of the target product, propylene, necessitates the combined action of acidic and metallic sites. Excessive acidic sites affect the desorption of propylene on acidic sites, while insufficient acidic sites affect the desorption of propylene on metallic sites. This study provides theoretical guidance for the design of PDH catalyst systems.
Plastic‐to‐Treasure: Innovative advances in photo/electro‐catalytic upcycling technologies for commodity chemicals and fuels
Authors: Leiu Yu Xuan , Lim Ke Ming , Chiah Zi‐Jing , Mah Elton Song‐Zhe , Ong Wee‐Jun 
Published: November 2024

AbstractPlastics are one of the greatest inventions of the 20th century that bring convenience to mankind. Owing to the commercialization of plastics, plastic pollution has become a petrifying environmental issue as the demand for plastic products overwhelms plastic recycling rates. However, the conventional methods (i.e., pyrolysis and gasification) require high pressure and temperature to treat waste plastic, resulting in ineluctably energy‐waste and secondary pollution. On the contrary, selective catalylic technologies provide a green approach to degrade plastics whilst also reforming them into value‐added chemicals and fuels. In this review, innovative green approaches, including photocatalysis, electrocatalysis, and photoelectrocatalysis, have been comprehensively reviewed from the perspective of sustainable use of resources. Distinctive emphasis is placed on highlighting the merits of each technology and enlightening the state‐of‐the‐art modification strategies that strengthen the pillars of catalytic activities. The transformation of plastics with the above techniques is also elaborated in terms of the reaction conditions and products from various plastic waste as substrates. With a feasibility breakdown for each technology displayed in this study, insights on the challenges and prospects of innovative green technologies for plastic upcycling are underscored as well to facilitate the society moving toward a plastic circular economy.
A discrete choice experiment: Understanding patient preferences for managing chronic non‐cancer pain
Authors: Campbell Gabrielle , Settumba Stella , Hopkins Ria , Nielsen Suzanne , Larance Briony , Bruno Raimondo , Cohen Milton , Degenhardt Louisa , Shanahan Marian 
Published: November 2024

AbstractBackgroundThe management of chronic non‐cancer pain (CNCP) is complex. Concerns about adverse effects associated with opioid pain medications and a lack of funding for holistic programs present challenges for decision‐making among clinicians and patients. Discrete choice experiments (DCE) are one way of assessing and valuing patient treatment preferences.MethodDCE attributes and levels were generated through qualitative research and included number of medicines, side effects from medicines, pain interference, care management, risk of addiction, activity goals, preferred source of information on pain management and willingness to pay. The survey was administered to participants with CNCP recruited through an existing cohort study (n = 442) and a sample of people living with CNCP recruited through Australia's leading pain advocacy body (Painaustralia) (n = 256).ResultsThe median age of participants was 58 years (SD 12.0), the majority were female. The analysis revealed two latent demographic classes: a younger group with higher levels of private health insurance and an older group with lower levels of private health insurance coverage. There were notable differences in preference. The younger cohort exhibited a greater willingness‐to‐pay to reduce pain interference, whereas the older group prioritized GP management, preferred more medicines and expressed fewer addiction concerns.ConclusionPatients' treatment preferences diverged based on age and insurance status, underscoring the importance of understanding patient perspectives in treatment communication and care coordination. These findings provide insight into patient decision‐making, which is important for promoting access to quality healthcare and engagement with evidence‐based treatment of CNCP.Significance StatementA discrete choice experiment identified two groups: younger, with more private insurance, and older, with less private health insurance, each with unique pain management preferences. Clinicians should be aware that age and private health insurance may have an impact on a patient's preferences for CNCP management.
Explaining and Predicting Momentum Performance Shifts Across Time and Sectors
Authors: Mamais Konstantinos , Thomakos Dimitrios , Vlamis Prodromos 
Published: November 2024

ABSTRACTIn this paper, we analyze the momentum of the NASDAQ and its major sectoral components across an extended period of key economic events, which include recessions, expansions, wars, financial crises, and the Covid‐19 health crisis. We seek to explain how momentum works as an investment strategy during different economic conditions and whether understanding how it works in‐sample can contribute to the out‐of‐sample forecasting of future financial performance. The novelty of our approach rests in the identification and exploitation of momentum characteristics that lead to the ranking of sectors depending on the period of economic activity that we are in. These rankings are tested and found to be robust for the in‐sample and the out‐of‐sample forecasting of financial performance, thus leading us to surmise that one can use the identification of past economic conditions to extrapolate for investing accordingly in the future. Our results indicate that this suggested approach works very well in practice and is, thus, a viable and fully interpretable investment strategy.
The Effect of glna Loss on the Physiological and Pathological Phenotype of Parkinson's Disease C. elegans
Authors: Liang Qifei , Zhao Guangrong 
Published: November 2024

ABSTRACTBackgroundParkinson's disease (PD) is a common neurodegenerative disease. Glutamate(Glu) excitotoxicity is one of the main pathogenesis of PD. Glutaminase (Gls) is an enzyme primarily responsible for catalyzing the hydrolysis and deamidation of glutamine (Gln) to produce Glu and ammonia. Inhibiting the function of Gls may have a beneficial effect on the treatment of PD by reducing the production of Glu. The homologous gene of Gls in C. elegans is glna.AimsTo explore the effects of glna loss on physiological and pathological phenotype of PD C. elegans, and to provide new ideas and references for the research and treatment of PD.Materials & MethodsWe used PD C. elegans UA44 and QIN27 to detect development and lifespan, behavior, degeneration of dopaminergic neurons, lipid levels, ROS levels, expression levels of common amino acids.ResultsGlna loss had no significant impact on the development and lifespan of PD C. elegans. Glna loss saved part of the decline of motor function, including the head thrash frequency and the body bend frequency, and the difference was significant. There was a trend of improvement in some motor behaviors, such as the ethanol avoidance experiment, while no improvement was observed in other experiments. Glna loss slowed down the degeneration of dopaminergic neurons. Glna loss increased the lipid levels and ROS levels in C. elegans. Glna loss decreased Glu content and increased Gln content in C. elegans.DiscussionThe effect of glna loss on PD C. elegans may be the result of multiple factors, such as the tissue types of α‐syn expression in C. elegans, the PD C. elegans model used, the adverse effects of glna loss on other systems, and the changes in ROS levels in C. elegans. The specific mechanisms causing these phenomena are still unclear and need to be further explored.ConclusionGlna loss has a certain protective effect on dopaminergic neurons in PD C. elegans, while the improvement effect on movement and behavior is limited.
Glycoengineered extracellular vesicles released from antibacterial hydrogel facilitate diabetic wound healing by promoting angiogenesis
Authors: Wang Kewei , He Qin , Yang Mengmeng , Qiao Qincheng , Chen Jun , Song Jia , Zang Nan , Hu Huiqing , Xia Longqing , Xiang Yingyue , Yan Fei , Hou Xinguo , Chen Li 
Published: November 2024

AbstractDiabetic wounds have become a global healthcare burden owing to impaired angiogenesis and persistent infections. Extracellular vesicles (EVs) can improve diabetic wounds, though their targeting ability is limited. In this study, we investigated the performance of a novel hydrogel dressing comprised of gelatin methacryloyl, glycoengineered EVs, and polylysine in treating infected diabetic wounds. High‐throughput single‐cell RNA sequencing (scRNA‐seq) and immunofluorescence staining revealed that E‐selectin (SELE) levels were higher in diabetic wounds than in non‐diabetic wounds. Mesenchymal stromal cells (MSCs) were transfected with a lentivirus containing fucosyltransferase VII (FUT7) and a CD63‐P19‐Nluc vector to enhance the expression of sialyl Lewis X (sLeX), the ligand of E‐selectin, on the surface of EVs (s‐EVs) derived from transfected MSCs (s‐MSCs). s‐EVs can target human umbilical vein endothelial cells (HUVECs) under lipopolysaccharide stimulation and promote the function of stimulated HUVECs in vitro. To promote and sustain the release of s‐EVs, we fabricated a gelatin methacryloyl (Gel)/poly‐L‐lysine methacryloyl (PL)‐5 hydrogel with good antibacterial ability, biocompatibility and mechanical properties. In a mouse experiment, s‐EV@Gel/PL‐5 exhibited excellent angiogenesis and anti‐inflammatory abilities and further promoted the healing of infected diabetic wounds. Our findings demonstrated the potential of the s‐EV@Gel/PL‐5 hydrogel in the clinical treatment of diabetic infectious wounds.
Coherent Control of Relativistic Electron Dynamics in Plasma Nanophotonics
Authors: Dulat Ankit , Rakeeb Sk , Dam Sagar , Lad Amit D. , Ved Yash M. , Kruk Sergey , Kumar G. Ravindra 
Published: November 2024

AbstractIntense femtosecond laser pulses interacting with solids can drive electrons to relativistic energies, enabling miniaturized particle accelerators and bright extreme‐UV light sources. In‐situ space‐time control of these electrons is crucial for developing next‐generation laser‐based accelerators but remains extremely challenging. A novel approach is presented to achieve such control by manipulating the local fields driving these electrons using a nanoengineered dielectric nanopillar target. Via experiments and simulations, it is demonstrated that this sub‐femtosecond and nanometer‐scale control enables enhanced electron acceleration and control of the directionality of relativistic electrons over a wide angular range and predicts the coherent formation of sub‐femtosecond electron bunches from the nanopillars. This research bridges nanophotonics and strong‐field plasma physics, offering new opportunities for in‐situ control of high‐energy particles and advancements in plasma technology.
Electrospinning of Cellulose Benzyl Carbamates for Enantioselective Membrane Filtration
Authors: Nono‐Tagne Steve , Heinze Thomas , Gericke Martin , Otsuka Issei 
Published: November 2024

AbstractElectrospun nanofibrous membranes made of chiral selectors (CSs) have shown their potential for efficient chiral resolutions via filtrations. It is thus of great importance to expand the number of electrospun membranes made of various CSs for the resolution of a wide range of chiral compounds. Here, the electrospinning of two benzyl carbamate derivatives of cellulose, namely cellulose benzyl carbamate (CBzC) and cellulose 4‐chlorobenzyl carbamate (CCBzC), to form a new type of enantioselective membranes for chiral resolutions of racemic compounds, is reported. The morphology of the electrospun membranes is studied by optical microscopy and scanning electron microscopy in relation to the electrospinning process parameters. Liquid‐liquid permeation experiments of the racemic compounds, (R,S)‐1‐(1‐naphthyl)ethanol ((R,S)‐NET), (R,S)‐1,1′‐bi‐2‐naphtol ((R,S)‐BNP), (R,S)‐naproxen ((R,S)‐NAP), and (R,S)‐benzoin ((R,S)‐BNZ) through the membranes demonstrate preferable permeations of (R)‐ or (S)‐enantiomers depending on the combinations between the CSs and the racemates. Molecular docking simulations indicate the differences in the binding type, number, and free energies between the CSs and the enantiomers.
Low‐Density Polyethylene Films Containing Cellulose‐Encapsulated Thymol With Prolonged Anti‐Mold Activity and Its Potential in Hay Preservation
Authors: Shlosman Koranit , Rein Dmitry M. , Shemesh Rotem , Caspi Ayelet , Kleinerman Olga , Cohen Yachin 
Published: November 2024

ABSTRACTThe use of many pesticides in agricultural crop protection has been banned due to their harmful effects on health and the environment, leaving farmers with limited crop protection options. A natural nontoxic alternative is thymol (TY), the main component in thyme essential oil (EO), which is known to have pesticidal and anti‐mold properties. TY can be incorporated into plastic films, widely used in agricultural applications. However, its volatility and susceptibility to heat limits its use in polymeric systems. By encapsulating TY using natural biopolymer such as cellulose, TY can be protected during high‐temperature plastic processing, thus enabling to achieve an active plastic packaging. In this study, cellulose‐encapsulated TY was melt‐compounded with low‐density polyethylene (LDPE) and 100 μm‐thick films were fabricated and compared with similar compounds containing free TY. Scanning electron microscopy with energy dispersive X‐ray spectroscopy confirmed the presence of TY‐loaded particles and demonstrated that they had no significant effects on the LDPE matrix morphology. LDPE films containing encapsulated TY offered higher anti‐mold protection functionality to postharvest alfalfa plants, in comparison to films containing free TY. Fourier transform infrared spectroscopy supported by thermo gravimetric analysis further confirmed successful incorporation of TY‐loaded particles in the LDPE films. Taken together, the application range of EOs and their synthetic compounds such as TY, can be broadened by encapsulation with cellulose. Incorporation of cellulose‐encapsulated TY in plastic composites can serve as a useful natural alternative to toxic pesticides in agricultural applications.
School Refusal and Determinants: Parental Psychopathology, Family Functioning, Attachment and Temperament
Authors: Eroglu Mehtap , Mentese Babayigit Tugba , Bilgen Ulgar Sermin , Ozturk Polat Ezgi , Erguven Demirtas Merve , Gul Alic Betül , Temelturk Duygu , Yaksi Nese 
Published: November 2024

ABSTRACTIn the current study investigated the psychopathologies of parents, family functioning, child temperament characteristics, and attachment of kindergarten and primary school‐age children who were brought to the child and adolescent psychiatry outpatient clinic due to school refusal behavior. Fifty‐two children with school refusal and 64 children without school refusal and their parents participated in the current study. School Refusal Assessment Scale, Systemic Family Functionality Scale(SFFS), Family Harmony Scale(FHS), Kerns Secure Attachment Scale(KSAS), Temperament Scale for Children(TSC), and Depression Anxiety Stress Scales(DASS) for parents were used. It was determined that, compared to children without school refusal, the children with school refusal had lower KSAS score(mother)(p = 0.049), higher DASS‐stress and anxiety(mother) scores(p = 0.014 and p = 0.020, respectively), lower TSC‐Responsiveness/Reactivity subscale score (p = 0.005), lower SFFS‐intrafamilial support and SFFS‐intrafamilial connection scores (p = 0.002 and p < 0.001, respectively), and lower FHS‐total score (p = 0.002). It was determined that school refusal was 11 times more common in children who had difficulty adjusting to school in previous years. Each point increase in the SFFS‐intrafamilial connection score reduced school refusal by 30%. In the current study shows that among the interventions required for treatment, the family should also be targeted in addition to the child and adolescent. Therefore, it is essential to identify factors such as parents' psychopathology and their roles in the family, family functioning, and family harmony in school refusal. Because parents play a crucial role in both the development and maintenance of school refusal, using more parent‐targeted strategies or techniques is necessary to improve interventions.
The High‐Resolution Structure of a Variable Lymphocyte Receptor From Petromyzon marinus Capable of Binding to the Brain Extracellular Matrix
Authors: Appelt Elizabeth A. , Thoden James B. , Gehrke Seth A. , Bachmeier Hannah D. , Rayment Ivan , Shusta Eric V. , Holden Hazel M. 
Published: November 2024

ABSTRACTVariable lymphocyte receptors (VLRs) are antigen receptors derived from the adaptive immune system of jawless vertebrates such as lamprey (Petromyzon marinus). First discovered in 2004, VLRs have been the subject of numerous biochemical and structural investigations. Due to their unique antigen binding properties, VLRs have been leveraged as possible drug delivery agents. One such VLR, previously identified and referred to as P1C10, was shown to bind to the brain extracellular matrix. Here, we present the high‐resolution X‐ray crystal structure of this VLR determined to 1.3 Å resolution. The fold is dominated by a six‐stranded mixed β‐sheet which provides a concave surface for possible antigen binding. Electron density corresponding to a 4‐(2‐hydroxyethyl)piperazine‐1‐propanesulfonic acid buffer molecule (HEPPS) was found in this region. By comparing the P1C10 molecular architecture and its buffer binding residues with those of other VLRs previously reported, it was possible to illustrate how this unique class of proteins can accommodate diverse binding partners. Additionally, we provide an analysis of the experimentally determined structure compared to the models generated by the commonly used AlphaFold and iTASSER structure prediction software packages.