bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infection prevention and control practices related to carbapenemase-producing Enterobacteriaceae (CPE) in acute-care hospitals in Ontario, Canada
Authors: Jamal Alainna J. , Garcia-Jeldes Felipe , Baqi Mahin , Borgia Sergio , Johnstone Jennie , Katz Kevin , Kohler Philipp , Muller Matthew P. , McGeer Allison J. ,   for the CPE Investigators of the Toronto Invasive Bacterial Diseases Network
Published: June 2019

AbstractObjective:To determine infection prevention and control (IPAC) practices for carbapenemase-producing Enterobacteriaceae (CPE), an emerging threat, at acute-care hospitals in Ontario, Canada.Design:A descriptive cross-sectional survey.Methods:We surveyed IPAC directors and managers at all acute-care hospitals in Ontario, Canada, to gather information on IPAC practices related to CPE, including admission screening, other patient screening, environmental testing, use of precautions to prevent transmission, and outbreak management.Results:Of 116 acute-care hospitals, 105 (91%) responded. Admission screening included patients previously colonized or infected with CPE (n = 64, 61%), patients recently hospitalized outside of Canada (Indian subcontinent, n = 62, 59%; other countries, n = 56, 53%), and patients recently hospitalized in Canada (n = 22, 21%). Fifty-one hospitals (49%) screened patients for colonization during an outbreak. Almost all hospitals (n = 101, 96%) used precautions to prevent transmission from patients with CPE colonization or infection; most hospitals (n = 54, 53%) continued precautions indefinitely. Few hospitals (n = 19, 18%) performed environmental cultures. Eight hospitals (8%) reported at least 1 outbreak, and 6 hospitals (6%) reported transmission from sink or shower drains to patients.Conclusions:Variability in practices may result from lack of evidence and challenges in updating guidelines as evidence emerges. A coordinated approach to slow the emergence of CPE should be considered in our population.
Growth performance and bone characteristics of broiler chickens fed corn-soy diet supplemented with different levels of vitamin premix and sources of mineral premix
Authors: Ao T. , Paul M.A. , Pescatore A.J. , Macalintal L.M. , Ford M.J. , Dawson K.A. 
Published: June 2019

SummaryInorganic trace mineral salts in the premix have a detrimental effect on the stability of vitamins due to redox reactions. A study was conducted to investigate the effect of dietary supplementation of different levels of vitamin premix with different mineral premixes on the performance and bone characteristics of broilers. A 2 x 2 factorial dietary treatment was used with two levels of vitamins and two types of minerals in the premix. A total of 1056, one-day old chicks were randomly assigned to four dietary treatments with 12 replicate pens of 22 chicks for 28 d. An interactive effect between vitamin levels and mineral sources on weight gain and feed intake of chickens was detected. Chickens fed the diet containing 100% vitamin premix with either source of mineral premix had higher (P &lt; 0.01) weight gain and feed intake than those fed the diet containing 30% vitamin premix with either source of mineral premix. However, the chickens fed the diet containing the 30% vitamin premix with the organic minerals had higher (P &lt; 0.01) weight gain and feed intake than those fed the diet containing 30% vitamin premix with inorganic minerals. Chickens fed the diet containing organic mineral premix had lower (P &lt; 0.05) mortality and feed to gain ratio and higher (P &lt; 0.01) bone breaking strength and ash content of tibia than those fed the inorganic mineral premix treatment. Chickens fed the diet containing 100% vitamin premix had higher (P &lt; 0.01) breaking strength of femur and tibia ash than those fed the diet containing 30% vitamin premix. The results from this trial indicated that total replacement of inorganic trace minerals with organic minerals can increase the storage stability of vitamins in feed premixes containing both vitamins and trace minerals, which is reflected in better growth performance in poultry.
Is age discrimination a less serious form of discrimination?
Authors: Goosey Stuart 
Published: June 2019

AbstractThe UK courts and the CJEU have often treated age discrimination as a less serious form of discrimination. This is reflected in the courts’ reluctance to offer rigorous scrutiny when evaluating whether age-differential treatment is objectively justified under anti-discrimination law. Further, a number of judges have asserted that age discrimination must be understood as different to other forms of discrimination, such as race or sex discrimination. This paper argues that age discrimination is not fundamentally different or prima facie less serious than other forms of discrimination. Age discrimination can undermine the same principles that paradigm forms of discrimination also undermine, including: creating inequality of opportunity by disadvantaging people because of a trait that is outside a person's control; undermining social equality by creating a hierarchy of social status between different groups; violating autonomy by diminishing people's capacity to have control over their lives; and communicating disrespect by conveying that particular groups have a diminished moral or social worth. It follows, contrary to the approach of much of the case law, that the courts should offer rigorous scrutiny of age-differential treatment to identify these harms and only permit age distinctions that are strictly tailored to enhance equality or other important values.
Tracing Carbon Isotope Variations in Lake Sediments Caused by Environmental Factors During the Past Century: A Case Study of Lake Tapeliai, Lithuania
Authors: Barisevičiūtė Rūta , Maceika Evaldas , Ežerinskis Žilvinas , Mažeika Jonas , Butkus Laurynas , Šapolaitė Justina , Garbaras Andrius , Paškauskas Ričardas , Jefanova Olga , Karosienė Jūratė , Kasperovičienė Jūratė , Remeikis Vidmantas 
Published: June 2019

ABSTRACTIn this study, we examined how land use and urbanization changes in adjacent areas affected biological productivity and carbon cycling in a lake ecosystem over 100 years and how these changes are reflected in carbon isotope variations. We performed radiocarbon (14C) activity and stable carbon isotope ratio analysis in two organic fractions: humin and humic acids of lake sediment. Additionally, we performed pigment and diatom analysis and determined the carbonate and organic matter (OM) content in sediments. Over the last century, the estimated 14C reservoir age in both sediment organic fractions varied from 1136 ± 112 yr to 5733 ± 122 yr. The increase in the reservoir age by 1175 ± 111 yr was related with higher inputs of pre-aged organic carbon and 14C depleted hard water due to the opening of the channel connecting two lakes. Nuclear weapons tests caused an increase in the reservoir age of up to 5421 ± 135 yr and 5733 ± 122 yr in humin and humic acids, respectively. 13C values in the humic acid fraction showed a tendency to decrease, depending on the content of autochthonous versus allochthonous OM in sediments, while changes in the sources of OM had a minor impact on the stable carbon isotope composition in the humin fraction.
CLASSIFICATION OF FINITE GROUPS VIA THEIR BREADTH
Authors: HEINEKEN HERMANN , RUSSO FRANCESCO G. 
Published: June 2019

AbstractLet k be a divisor of a finite group G and Lk(G) = {x ∈ G | xk =1}. Frobenius proved that the number |Lk(G)| is always divisible by k. The following inverse problem is considered: for a given integer n, find all groups G such that max{k-1|Lk(G)| | k ∈ Div(G)} = n, where Div(G) denotes the set of all divisors of |G|. A procedure beginning with (in a sense) minimal members and deducing the remaining ones is outlined and executed for n=8.
Norovirus waterborne outbreak in Chalkidiki, Greece, 2015: detection of GI.P2_GI.2 and GII.P16_GII.13 unusual strains
Authors: Tryfinopoulou K. , Kyritsi M. , Mellou K. , Kolokythopoulou F. , Mouchtouri V.A. , Potamiti-Komi M. , Lamprou A. , Georgakopoulou Th. , Hadjichristodoulou C. 
Published: June 2019

AbstractNoroviruses, along with rotaviruses, are among the leading causes of gastroenteritis worldwide and novel strains are periodically emerging. In August 2015, an unusual increase of gastroenteritis cases occurred in a touristic district in Kassandra peninsula, Chalkidiki, Northern Greece. Seven stool specimens from cases were tested positive for norovirus. Molecular investigation and phylogenetic analysis identified that there was co-circulation of norovirus GI.P2_GI.2 and the recombinant strain GII.P16_GII.13. A 1:1 case–control study conducted and showed that tap water consumption significantly associated with developing symptoms of gastroenteritis (odds ratio = 36.9,P= 0.018). The results of the epidemiological investigation, the co-circulation of two different norovirus strains, the information of a pipeline breakage at the water supply system before the onset of cases, and reports on flooded wells and sewage overflow, indicated the possibility of water contamination by sewage during the pipeline breakage leading to a large outbreak with a peak at 10 August and a possible secondary person-to-person transmission after the 16th of August. Norovirus GI.P2_GI.2 strains are rarely reported in Europe, while it is the first time that infection from the recombinant strain GII.P16_GII.13 is recorded in Greece.
Meningococcal carriage by age in the African meningitis belt: a systematic review and meta-analysis
Authors: Cooper L. V. , Kristiansen P. A. , Christensen H. , Karachaliou A. , Trotter C. L. 
Published: June 2019

Abstract
Meningococcal carriage dynamics drive patterns of invasive disease. The distribution of carriage by age has been well described in Europe, but not in the African meningitis belt, a region characterised by frequent epidemics of meningitis. We aimed to estimate the age-specific prevalence of meningococcal carriage by season in the African meningitis belt. We searched PubMed, Web of Science, the Cochrane Library and grey literature for papers reporting carriage of Neisseria meningitidis in defined age groups in the African meningitis belt. We used a mixed-effects logistic regression to model meningococcal carriage prevalence as a function of age, adjusting for season, location and year. Carriage prevalence increased from low prevalence in infants (0.595% in the rainy season, 95% CI 0.482–0.852%) to a broad peak at age 10 (1.94%, 95% CI 1.87–2.47%), then decreased in adolescence. The odds of carriage were significantly increased during the dry season (OR 1.5 95% CI 1.4–1.7) and during outbreaks (OR 6.7 95% CI 1.6–29). Meningococcal carriage in the African meningitis belt peaks at a younger age compared to Europe. This is consistent with contact studies in Africa, which show that children 10–14 years have the highest frequency of contacts. Targeting older children in Africa for conjugate vaccination may be effective in reducing meningococcal transmission.
A natural barrier in random greedy hypergraph matching
Authors: Bennett Patrick , Bohman Tom 
Published: June 2019

AbstractLetr⩾ 2 be a fixed constant and let$ {\cal H} $be anr-uniform,D-regular hypergraph onNvertices. Assume further thatD→ ∞ asN→ ∞ and that degrees of pairs of vertices in$ {\cal H} $are at mostLwhereL=D/( logN)ω(1). We consider the random greedy algorithm for forming a matching in$ {\cal H} $. We choose a matching at random by iteratively choosing edges uniformly at random to be in the matching and deleting all edges that share at least one vertex with a chosen edge before moving on to the next choice. This process terminates when there are no edges remaining in the graph. We show that with high probability the proportion of vertices of$ {\cal H} $that are not saturated by the final matching is at most (L/D)(1/(2(r−1)))+o(1). This point is a natural barrier in the analysis of the random greedy hypergraph matching process.
Molding the shape of congenial and structural interventional cardiology: interviews with directors of major congresses
Authors: Goreczny Sebastian , Hijazi Ziyad M. , Qureshi Shakeel A. , Carminati Mario , Kenny Damien , Morgan Gareth J. 
Published: June 2019

AbstractThe range and number of educational and networking events that are available for fellows, trainees, and junior faculty to attend grows every year. Each meeting useful in its own way; each adding value to the development and the growth of an interventionist. Within paediatric, congenital, and structural heart disease, three of the standout meetings are: Pediatric and Interventional Cardiac Symposium (PICS-AICS), Congenital and Structural Interventions (CSI), and International Workshop on Interventional Pediatric and Adult Congenital Cardiology (IPC). All of these were started by leaders in our field; people known to be passionate educators and innovators. International congresses focusing more broadly on congenital cardiac disease in children and adults are rare. These forums allow more interdisciplinary discussions between the interventionist, surgeon, and non-invasive specialists. Purely interventional meetings are essential to allow colleagues to debate and explore the nuances and intricacies of technique and approach, developing concepts to be challenged in wider forums. During the recent 21st PICS-AICS meeting Prof. Ziyad M. Hijazi, Shakeel A. Qureshi, Mario Carminati, and Dr Damien Kenny shared their time to engage in frank, recorded conversations which provide a unique insight in to the process and concepts behind three of our most important educational congresses.
The Carle-Illinois (Urbana, Illinois USA) Treatment Protocol for Law Enforcement K9s: Guidelines for Emergency Medical Services
Authors: Mitek Ashley E. , McMichael Maureen A. , Weir William B. , Smith Michael J. , Schneider Danielle C. 
Published: June 2019

AbstractThis document is a resource for Emergency Medical Services (EMS) treating an injured law enforcement K9 (LEK9) in the field and/or during transport by ambulance to a veterinary hospital. A Joint Task Force on Working Dog Care was created, which included veterinarians, EMS directors, EMS physicians, and canine handlers, who met to develop a treatment protocol for injured LEK9s. The protocol covers many major life-threatening injuries that LEK9s may sustain in the line of duty, and also discusses personnel safety and necessary equipment. This protocol may help train EMS providers to save the life of an injured LEK9.
Satellite Observations of the Diurnal Dynamics of Particulate Organic Carbon in Optically Complex Coastal Oceans: The Continental Shelf Seas of China
Authors: Wei Xiaodao , Shen Fang , Pan Yanqun , Chen Shuguo , Sun Xuerong , Wang Yongchao 
Published: June 2019

AbstractThe continental shelf seas of China (CSSC) broadly encompass the Bohai Sea, the Yellow Sea, and the East China Sea and exhibit highly variable optical properties. Accurate satellite estimates of particulate organic carbon (POC) remain challenging because optimal proxies for remotely sensed POC are largely obscure in these optically complex coastal waters. In this study, optical and biogeochemical data, including the particulate beam attenuation coefficient (cp), particulate backscattering coefficient (bbp), remote sensing reflectance (Rrs), POC, total suspended matter (TSM), and chlorophyll‐a (Chla), were collected over multiple seasons and years in the CSSC. We first classified the study area into three different water types with three different POC retrieval proxies: the TSM for high‐TSM waters, Chla for low‐TSM waters, and Rrs ratio (Rrs(490)/Rrs(555)) for moderate‐TSM waters. A composite POC algorithm using these three optimal proxies was then developed for Geostationary Ocean Color Imager (GOCI) satellite data (hereafter called the POC_CSSC algorithm). The validation results indicated that the accuracy of GOCI‐derived POC was greatly improved with a mean relative error of 32.08%. Application of the POC_CSSC algorithm to GOCI data over a tidally impacted estuary demonstrated the robustness of the algorithm and that tides play different roles in the broad CSSC. More specifically, tides have the strongest influence on nearshore estuarine waters, regulating the progression of high‐POC water masses from estuary to offshore environments, while offshore waters were the least influenced by tides with less variable, low POC concentrations.
Exchange of Water Between the Ross Gyre and ACC Assessed by Lagrangian Particle Tracking
Authors: Roach Christopher J. , Speer Kevin 
Published: June 2019

AbstractTo reach upwelling and downwelling zones deep within the Southern Ocean seasonal sea ice cover, water masses must move across the Antarctic Circumpolar Current and through current systems including the Ross Gyre, Weddell Gyre, and Antarctic Slope Current. In this study we focus our attention on the Lagrangian exchange between the Ross Gyre and surrounding current systems. We conducted numerical experiments using five‐day 3‐D velocity fields from the Southern Ocean State Estimate with a particle tracking package to identify pathways by which waters move from near the Antarctic coastal margins or Antarctic Circumpolar Current into the interior of the Ross Gyre, and to identify the time scales of variability associated with these pathways. Waters from near the Antarctic margins enter the Ross Gyre along the western and northern boundaries of gyre until the gyre separates from the Pacific‐Antarctic Ridge near fracture zones. At this juncture, Antarctic Circumpolar Current‐derived inflow dominates the across‐gyre transport up to the Antarctic margin. Transport and exchange associated with different time‐average components of flow are calculated to determine the relative contributions of high‐ and low‐frequency and time‐mean components.
Can Convolution and Deconvolution Be Used as Tools for Modeling Multicomponent, Mixing‐Limited Reaction Networks?
Authors: Engdahl Nicholas B. , McCallum James L. , Ginn Timothy R. 
Published: June 2019

AbstractTransfer functions (i.e., convolutions) have been powerful tools for both forward modeling and reconstructing past states of transport systems in a wide range of subsurface flow problems. The advantage of the transfer function is that it is a simple alternative to complicated, distributed parameter models of flow and transport, but the majority of applications of transfer functions in hydrology have been limited to relatively simple cases, like passive tracers or first‐order decay. The central question evaluated in this note is whether or not multicomponent mixing‐limited reactive transport can be represented within a transfer function framework. Our examples consider forward‐in‐time predictions and backward‐in‐time reconstructions of a carbonate system that represents the intrusion of seawater into a freshwater aquifer. The main result is that accurate forward‐in‐time and backward‐in‐time models are developed by posing the problem in terms of conservative components. As with all convolution‐based methods, the results are sensitive to errors and/or noise in the input functions, but we show that smoothed approximations of the requisite functions provide good representations of transport. Given the vast unknowns in any subsurface transport problem, such generalized, reactive transfer function models may have yet unexplored advantages when the trade‐offs between overall computational cost, accuracy, and uncertainty are explored in more detail.
Coupled External‐Internal Dynamics of Layered Circulation in the South China Sea: A Modeling Study
Authors: Cai Zhongya , Gan Jianping 
Published: June 2019

AbstractThe external inflow/outflow through straits on the periphery of the South China Sea (SCS) and the associated internal response of vertical transport over the broad continental slope form and sustain a cyclonic‐anticyclonic‐cyclonic (CAC) circulation in the upper‐middle‐lower layer in the SCS. We conduct a process‐oriented numerical study to investigate the underlying coupled external‐internal dynamics that remains unknown, despite that the dynamics plays a critical role in forming and sustaining the CAC circulation. External sandwich‐like inflow‐outflow‐inflow in the water column through the Luzon Strait forms a three‐dimensional CAC slope current over the curving slope topography in the SCS basin, in which the downward/upward transport associated with the cross‐slope motion is established. The along‐slope current over the basin provides vorticity through the beta effect and accounts for the most external planetary vorticity input through the strait in the upper layer of the SCS, while the vorticity induced by the vertical transport is the major response to the external vorticity flux in the middle and lower layers. We illustrate the critical role of the vertical transport in linking the vorticity among the different layers for the development and sustenance of the CAC circulation. The vertical transport is associated with the cross‐slope motion due to slope current‐topography interaction, which involves mainly in bottom frictional transport and geostrophic cross‐isobath transport by the pressure gradient force in the along‐slope direction. Pressure gradient force is generated by nonlinear vorticity advection and the beta effect of the background slope current.
Phosphate availability affects fixed nitrogen transfer from diazotrophs to their epibionts
Authors: Schoffelen Niels J , Mohr Wiebke , Ferdelman Timothy G , Duerschlag Julia , Littmann Sten , Ploug Helle , Kuypers Marcel M M 
Published: June 2019

Abstract
Dinitrogen (N2) fixation is a major source of external nitrogen (N) to aquatic ecosystems and therefore exerts control over productivity. Studies have shown that N2 -fixers release freshly fixed N into the environment, but the causes for this N release are largely unclear. Here, we show that the availability of phosphate can directly affect the transfer of freshly fixed N to epibionts in filamentous, diazotrophic cyanobacteria. Stable-isotope incubations coupled to single-cell analyses showed that &lt;1% and ~15% of freshly fixed N was transferred to epibionts of Aphanizomenon and Nodularia, respectively, at phosphate scarcity during a summer bloom in the Baltic Sea. When phosphate was added, the transfer of freshly fixed N to epibionts dropped to about half for Nodularia, whereas the release from Aphanizomenon increased slightly. At the same time, the growth rate of Nodularia roughly doubled, indicating that less freshly fixed N was released and was used for biomass production instead. Phosphate scarcity and the resulting release of freshly fixed N could explain the heavy colonization of Nodularia filaments by microorganisms during summer blooms. As such, the availability of phosphate may directly affect the partitioning of fixed N2 in colonies of diazotrophic cyanobacteria and may impact the interactions with their microbiome.