bluuebunny/crossref_metadata_2025_split huggingface dataset:
From candidate to president: Donald Trump's effect on an executive coaching client
Authors: Thomas Laurie 
Published: March 2018

AbstractPolitical events leading up to, and following the results of, the November, 2016 election have affected patients in psychotherapy as well as clients working with executive coaches. This article follows developments in coaching work with one male, middle‐aged, highly successful but “interpersonally challenged” client that are traceable to the client's reactions to the election and to the president himself.
Backpackers in the Nepal 2015 earthquake: The contribution of personal and social resources to mental health
Authors: Weiss‐Dagan Shlomit , Itzhaky Haya , Taubman‐Ben‐Ari Orit 
Published: March 2018

AbstractPsychologists and social workers are usually called into action after natural disasters such as earthquakes, which obviously arouse psychological distress among locals. However, the question of assisting tourists who have also been affected by the disaster has scarcely been studied. In this study, we focused specifically on backpackers who were in Nepal at the time of the 2015 earthquake, and survived. Our aim was to estimate factors that protect a backpacker's mental health after an earthquake, to deepen social workers’ knowledge regarding potential effective interventions. Based on the conservation of resources theory, we examined the contribution of optimism, emotion regulation, as well as the support of family and friends to backpackers’ mental health. A cross‐sectional sample survey was conducted to collect data from 145 backpackers 1 week to 3 months after the disaster. The findings indicated that optimism, emotion regulation in the form of reassessment, and friends’ support contributed positively to backpackers’ mental health, whereas suppression of expression contributed negatively. Findings are discussed with the aim of providing recommendations for social workers.
Research advances and challenges in anammox immobilization for autotrophic nitrogen removal
Authors: Manonmani Umapathy , Joseph Kurian 
Published: March 2018

AbstractApplication of the anaerobic ammonium oxidation (anammox) process using suspended or attached growth technology has limitations of slow growth rate such as biomass washout, and large footprint. This has led to the development of smaller, compact immobilized systems. In recent years, wastewater treatment using anammox immobilized cells has received much attention due to its advantages of high biomass content, retention of biomass by prevention of washout, good solid–liquid separation and lower toxicity to microorganisms. This article critically reviews the existing literature on autotrophic nitrogen removal using anammox bacteria in its immobilized form. Different methods of using immobilized anammox bacteria were identified. Characteristics of various polymeric gels such as solubility, biodegradability, stability, diffusivity and growth of biomass in the polymeric gel were studied. However, there is insufficient study of disposal methods and costs involved in anammox immobilization to guide future implementation of immobilized anammox technologies for autotrophic nitrogen removal. © 2018 Society of Chemical Industry
Sonographic diagnosis of four water beads causing small‐bowel obstruction in an 18‐month‐old boy
Authors: Yang Xiuzhen , Zhang Yuebin , Ye Jingjing 
Published: March 2018

AbstractWe report a rare case of sonographic (US) diagnosis of four water beads causing small‐bowel obstruction in an 18‐month‐old boy. The boy presented with a 3‐day history of repeated bouts of abdominal pain and vomiting, which became bilious on the last day. Abdominal US examination showed four rounded anechoic masses in the small bowel. Urgent exploratory laparotomy revealed that the obstruction was caused by three large water beads with a diameter of 2.8 cm and fragments of a fourth one. Foreign bodies should be considered in cases of small‐bowel obstruction; US can be very helpful in the diagnosis of water beads in the bowel.
Relationship between inferior vena cava diameter ratio and central venous pressure
Authors: Zhang Qing , Wang Xiaoting , Su Longxiang , Zhang Hongmin , Chai Wenzhao , Chao Yangong , He Wei , Liu Dawei 
Published: March 2018

AbstractPurposeTo explore the relationship between the shape of the inferior vena cava (IVC) lumen and central venous pressure (CVP).MethodsIn 60 patients undergoing mechanical ventilation and CVP monitoring in the Intensive Care Unit of Peking Union Medical College Hospital from July to October 2016, we measured with B‐mode ultrasonography the transverse maximum (MXD) and minimum diameter (MID) of the IVC at end expiration, and calculated the diameter ratio (DR) as MXD/MID. Patients were divided into three groups according to CVP: low (CVP < 8 mm Hg), intermediate (8 mm Hg ≤ CVP ≤ 10 mm Hg), and high (CVP > 10 mm Hg).ResultsMXD was 2.32 ± 0.41 cm, MID was 1.41 ± 0.40 cm, and DR was 1.76 ± 0.49. CVP was 9.27 ± 2.99 mm Hg. DR correlated with CVP (r = −0.527, P < .001). The low‐CVP group had greater dispersion of DR values, with a large variety in IVC shape (elliptical, irregular, teardrop‐shaped, partially collapsed…). The area under the ROC curve for predicting CVP with DR, with a CVP threshold of 8 mm Hg was 0.835 (95% CI, 0.726–0.945; P < .05). With a DR cutoff value of 1.76, sensitivity was 0.765 and specificity was 0.781.ConclusionsDR above 1.7 is predictive of CVP < 8 mm Hg.
Distribution and ultrastructure of the antennal sensilla of the grape weevil Naupactus xanthographus (Coleoptera: Curculionidae)
Authors: Vera Waleska , Bergmann Jan 
Published: March 2018

AbstractThe grape weevil, Naupactus xanthographus Germar (Coleoptera: Curculionidae), is a polyphagous insect native to southern South America that causes considerable damage in grape and other fruit species. In this study, the morphology and ultrastructure of the antennae and the antennal sensilla of N. xanthographus were investigated using scanning electron microscopy and transmission electron microscopy. The antennae consist of a scape, a pedicel, a funicle, and a zone called the “club,” which are all formed by a total of 12 antennomers. Different types of sensilla were observed: sensilla trichoidea, sensilla chaetica type 1 and 2, sensilla basiconica, and sensilla rod‐like. No sexual dimorphism was observed. The possible functions of the sensilla are discussed in relation to their morphology and ultrastructure.
“A disease of our time”: The Catholic Church's condemnation and absolution of psychoanalysis (1924–1975)
Authors: Foschi Renato , Innamorati Marco , Taradel Ruggero 
Published: March 2018

AbstractThe present paper is focused on the evolution of the position of the Catholic Church toward psychoanalysis. Even before Freud's The Future of an Illusion (1927), psychoanalysis was criticized by Catholic theologians. Psychoanalysis was viewed with either contempt or with indifference, but nonpsychoanalytic psychotherapy was accepted, especially for pastoral use. Freudian theory remained for most Catholics a delicate and dangerous subject for a long time. From the center to the periphery of the Vatican, Catholic positions against psychoanalysis have varied in the way that theological stances have varied. In the middle decades of the twentieth century, some Catholics changed their attitudes and even practiced psychoanalysis, challenging the interdict of the Holy Office, which prohibited psychoanalytic practice until 1961. During the Cold War, psychoanalysis progressively became more and more relevant within Catholic culture for two main reasons: changes in psychoanalytic doctrine (which began to stress sexuality to a lesser degree) and the increasing number of Catholic psychoanalysts, even among priests. Between the 1960s and the 1970s, psychoanalysis was eventually accepted and became the main topic of a famous speech by Pope Paul VI. This paper illustrates how this acceptance was a sort of unofficial endorsement of a movement that had already won acceptance within the Church. The situation was fostered by people like Maryse Choisy or Leonardo Ancona, who had advocated within the Church for a sui generis use of psychoanalysis (e.g., proposing a desexualized version of Freudian theories), despite warnings and prohibitions from the hierarchies of the Church.
Successful catheter ablation of ventricular premature complexes from the right atrial side of the atrioventricular septum with good contact force
Authors: Arai Marina , Fukamizu Seiji , Kawamura Iwanari , Miyazawa Satoshi , Hojo Rintaro , Sakurada Harumizu , Hiraoka Masayasu 
Published: March 2018

AbstractThe acquisition of good contact force for radiofrequency catheter ablation of ventricular premature complexes (VPCs) originating from the basal septum of the left ventricle (LV) is often difficult. We describe a case of VPCs originating from the basal septum of the LV, which were successfully eliminated by applying radiofrequency at the right atrium (RA) side of the atrioventricular septum (AVS) without causing any significant impairment of atrioventricular conduction because the ablation catheter could obtain better contact force through the RA approach. Moreover, intracardiac echocardiography (ICE) and RA angiography effectively demonstrated the AVS.
Effects of freezing conditions on quality changes in blueberries
Authors: Cao Xuehui , Zhang Fangfang , Zhao Dongyu , Zhu Danshi , Li Jianrong 
Published: March 2018

AbstractBACKGROUNDFreezing preservation is one of the most effective methods used to maintain the flavour and nutritional value of fruit. This research studied the effects of different freezing conditions, −20 °C, −40 °C, −80 °C, and immersion in liquid nitrogen, on quality changes of freeze–thawed blueberries. The water distribution estimates of blueberries were measured based on low‐field nuclear magnetic resonance (LF‐NMR) analysis. The pectin content, drip loss, and fruit texture were also detected to evaluate quality changes in samples.RESULTSThe freezing curves of blueberry showed super‐cooling points at −20 °C and − 40 °C, whereas super‐cooling points were not observed at −80 °C or in liquid nitrogen. After freeze–thaw treatment, the relaxation time of the cell wall water (T21), cytoplasm water and extracellular space (T22), and vacuole water (T23) were significantly shortened compared to fresh samples, which suggested a lower liquidity. Although the freezing speed for samples immersed in liquid nitrogen was faster than other treatments, samples treated at −80 °C showed better quality regarding vacuole water holding, drip loss, and original pectin content retention.CONCLUSIONThis study contributed to understanding how freezing temperature affects the qualities of blueberries. The super‐fast freezing rate might injure fruit, and an appropriate freezing rate could better preserve blueberries. © 2018 Society of Chemical Industry
Mathematical model of CO2 release during milk fermentation using natural kefir grains
Authors: Goršek Andreja , Ritonja Jožef , Pečar Darja 
Published: March 2018

AbstractBACKGROUNDMilk fermentation takes place in the presence of various micro‐organisms, producing a variety of dairy products. The oldest of them is kefir, which is usually produced by the fermentation of milk with kefir grains. Carbon dioxide (CO2), as one of the process products, also contributes to the characteristic flavor of kefir. The amount of CO2 generated during fermentation depends on bioprocessing conditions and may change, which is not desirable at the industrial level.RESULTSIn this study we developed a simplified mathematical model of CO2 release in the milk‐fermentation process. An intuitive approach based on superposition and experimental analysis was used for the modeling. The chemical system studied was considered as a two‐input (temperature, rotational frequency of the stirrer) one‐output (CO2 concentration) dynamic system.CONCLUSIONBased on an analysis of CO2 release transients in the case of non‐simultaneous stepwise changed input quantities, two differential equations were defined that describe the influence of the two input quantities on the output quantity. The simulation results were verified by experiments. The proposed model can be used for a comprehensive analysis of the process that is being studied and for the design and synthesis of advanced control systems, which will ensure a controlled CO2 release at the industrial level. © 2018 Society of Chemical Industry
Development of an orange juice beverage formulated with oat beta‐glucan and whey protein isolate
Authors: Wan Wenjing , Xu Baojun 
Published: March 2018

AbstractBACKGROUNDA beverage was developed using beta‐glucan and whey protein isolate (WPI). The sensory attributes and changes of the physiochemical properties (pH value, total acidity, total soluble solids, sugar‐acid ratio, color, viscosity, turbidity, and browning index) of the beverage during 48‐h storage were evaluated by comparison with the commercial product and a blank sample.RESULTSThe sweetness, smoothness, and overall acceptance of the developed beverage were similar to the commercial and blank samples. The suspension stability of the developed beverage was significantly better than that of the commercial products. The total acidity of the beverage decreased considerably after 36‐h storage. Regarding color changes, the three samples showed a significant increase inLandbvalues after 6 h of storage. The viscosity of the developed beverage rose significantly after 24 h of storage. The increase in the concentration of beta‐glucan in the mixed hydrocolloid caused a significant elevation in the levels of viscosity.CONCLUSIONThe sensory and physicochemical analysis results obtained by the panelists revealed that the developed beverage was acceptable and possessed stable physicochemical attributes. Our present findings indicate that the developed beverage has excellent potential for commercialization. © 2018 Society of Chemical Industry
Could OX40 agonist antibody promote activation of the anti‐tumor immune response in gastric cancer?
Authors: Martins Mário R. , Santos Rogério L. d. , Jatahy Kleber d. N. , Matta Marina C. d. , Batista Thales P. , Júnior José Iran C. , Begnami Maria D. F. S. , Torres Leuridan C. 
Published: March 2018

Background and ObjectivesOX40, a membrane‐bound molecule of the tumor‐necrosis‐factor‐receptor superfamily, is a critical costimulatory receptor during the immune response, especially to T cells, but studies described their presence of OX‐40 on neutrophils and monocytes, suggesting a potential role in the activation of immune response. Our aim was to characterize costimulatory receptors OX40 expression on circulating leukocytes in gastric cancer to identify novel targets for immunotherapy.MethodsPeripheral blood mononuclear cells were isolated from 24 gastric cancer patients and 34 healthy controls and the expression of costimulatory (OX40) receptors were analyzed on T cells, neutrophil and monocyte using monoclonal antibodies by flow cytometry.ResultsWe found that the higher levels of OX40 + T cells, monocytes/OX40+ and neutrophils/OX40+ from gastric cancer patients when compared to controls (P < 0.0001), and also higher levels of OX40+ T cells when compared to stages III and IV (P  = 0.02). Percentage levels of total T cells were similar between patients and controls.ConclusionsOX40 as a therapeutic agent has been investigated in many preclinical tumor models. Our findings suggest that of levels of costimulatory in T cells in GC will direct future studies on the role that costimulatory receptors play in the failure of T cell‐mediated immunity.
Evaluating Z Scores to Quantify Levator Hiatal Distensibility by 3‐Dimensional Ultrasonography in Nulliparas and Women With Pelvic Organ Prolapse
Authors: Wen Lieming , Liu Minghui , Zhao Baihua , Qing Zhenzhen 
Published: March 2018

ObjectivesTo use Z scores to quantify hiatal distensibility and to test the performance of Z scores for levator hiatal areas in predicting substantial pelvic organ prolapse (POP).MethodsWe undertook a retrospective study of the data from 145 nulliparas and 166 patients with POP who had a clinical POP examination with 3‐dimensional translabial ultrasonography. Z scores were used to normalize levator hiatal areas of nulliparas. The Z score model for the hiatal area was built by the formula Z score = (measured value – predicted mean value)/predicted standard deviation and was used to evaluate hiatal ballooning in women with POP.ResultsValid data were gathered from 134 nulliparas and 159 patients with POP. POP stage 1 was found in 46 women, stage 2 in 62, stage 3 in 43, and stage 4 in 8. We built the Z score model as follows: Z‐Av = (measured value – 17.15)/3.11, where Av represented the minimal levator hiatal area on the maximum Valsalva maneuver. The levator hiatal area was strongly related to the POP stage (P < .001). On a receiver operating characteristic curve analysis, the cutoff of Z‐Av was 1 for POP stage 2 or higher (sensitivity, 77%; specificity, 60%) and substantial POP on ultrasonography (sensitivity, 84%; specificity, 75%).ConclusionsHiatal distensibility can be exactly evaluated by Z‐Av. A Z‐Av value of less than 1.0 was defined as a “normal hiatal expansion,” 1 to 3 as “mild ballooning,” 3 to 5 as “moderate ballooning,” 5 to 7 as “marked ballooning,” and 7 or greater as “severe ballooning.”
Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent
Authors: Rizvi Imran , Obaid Girgis , Bano Shazia , Hasan Tayyaba , Kessel David 
Published: March 2018

ObjectiveA relatively low level of lysosomal photodamage has been shown capable of promoting the efficacy of photodamage simultaneously or subsequently directed to mitochondrial/ER sites. The procedure has hitherto involved the use of two photosensitizing agents that require irradiation at two different wavelengths and different formulation techniques. This, together with different pharmacokinetic profiles of the photosensitizers, adds a layer of complexity to a protocol that we have sought to circumvent. In this study, liposomal formulations were used to direct photodamage created by benzoporphyrin derivative (BPD, Verteporfin) to lysosomes, mitochondria and the ER. This resulted in the development of an optimal targeting profile using a single agent and a single wavelength of activating irradiation.Materials/MethodsThese studies were carried out in monolayer cultures of OVCAR5 tumor cells. BPD localization was modified by lipid anchoring and formulation in liposomes, and was assessed by fluorescence microscopy. Irradiation was carried out at 690 ± 10 nm with photodamage assessed also using fluorescent probes and microscopy.ResultsBPD normally localizes in a wide variety of sub‐cellular loci that include both mitochondria and the ER, but lysosomes are spared from photodamage. Using a liposomal formulation containing BPD anchored to a lipid resulted in the targeting of lysosomes. A mixture of liposomes containing “free” and “anchored” BPD was shown to significantly promote photokilling. Eliminating cholesterol from the formulation of the anchored product enhanced lysosomal photodamage; prior studies had revealed that excess cholesterol can have a cytoprotective effect when lysosomes are the PDT target.DiscussionThe ability of a liposomal formulation to change localization patterns permits directing photodynamic therapy toward specific sub‐cellular loci, thereby promoting photokilling. Incorporating chemotherapeutic agents into such formulations could represent a logical next step in assessing the ability of directed photodamage to enhance tumor eradication. Lasers Surg. Med. 50:499–505, 2018. © 2018 Wiley Periodicals, Inc.
Glycidyl Triazolyl Polymers: Poly(ethylene glycol) Derivatives Functionalized by Azide–Alkyne Cycloaddition Reaction
Authors: Ikeda Taichi 
Published: March 2018

AbstractGlycidyl triazolyl polymer (GTP), which is the product of the Huisgen dipolar cycloaddition reaction between glycidyl azide polymer and alkyne derivatives, is featured here. GTP is the multifunctionalized poly(ethylene glycol) (PEG). The drawback of PEG is that linear PEG has the functional group only at both ends. The low loading capability of the functional groups limits the possibilities of PEG applications. GTP facilitates the synthesis of multifunctionalized PEG derivatives. In this article, 74 examples of GTP homopolymers and copolymers are introduced. The synthetic protocols and work‐up processes of GTP are summarized. In addition, application studies are reviewed: for example, stimuli‐responsive and self‐healing materials, materials for electrical memory devices, ion‐conductive materials, and biomedical materials. Finally, some issues on GTP synthesis and future directions for GTP‐based polymer materials are proposed.
Potential lymphangiogenesis therapies: Learning from current antiangiogenesis therapies—A review
Authors: Yamakawa Michael , Doh Susan J. , Santosa Samuel M. , Montana Mario , Qin Ellen C. , Kong Hyunjoon , Han Kyu‐Yeon , Yu Charles , Rosenblatt Mark I. , Kazlauskas Andrius , Chang Jin‐Hong , Azar Dimitri T. 
Published: March 2018

AbstractIn recent years, lymphangiogenesis, the process of lymphatic vessel formation from existing lymph vessels, has been demonstrated to have a significant role in diverse pathologies, including cancer metastasis, organ graft rejection, and lymphedema. Our understanding of the mechanisms of lymphangiogenesis has advanced on the heels of studies demonstrating vascular endothelial growth factor C as a central pro‐lymphangiogenic regulator and others identifying multiple lymphatic endothelial biomarkers. Despite these breakthroughs and a growing appreciation of the signaling events that govern the lymphangiogenic process, there are no FDA‐approved drugs that target lymphangiogenesis. In this review, we reflect on the lessons available from the development of antiangiogenic therapies (26 FDA‐approved drugs to date), review current lymphangiogenesis research including nanotechnology in therapeutic drug delivery and imaging, and discuss molecules in the lymphangiogenic pathway that are promising therapeutic targets.
Time‐of‐flight MR‐angiography with a helical trajectory and slice‐super‐resolution reconstruction
Authors: Okanovic Melisa , Hillig Burghard , Breuer Felix , Jakob Peter , Blaimer Martin 
Published: March 2018

PurposeTo improve 2D noncontrast‐enhanced MRA by using a helical time‐of‐flight (TOF) acquisition technique and a slice‐super‐resolution reconstruction.MethodsThe TOF technique is combined with a helical trajectory with golden‐angle–based radial projection reordering. A continuous spatial shift in slice direction is realized by adjusting the frequency of the excitation pulse between the individual projections. The limited resolution along the shift direction is improved by a deconvolution with simulated slice profile. The helical TOF (hTOF) was compared in vivo with a conventional 2D and 3D TOF.ResultsResults from in vivo experiments on the carotid show that the visual resolution in slice direction can be improved by using hTOF and the slice‐super‐resolution reconstruction. The vessels appear up to 1.5 times sharper and can be better separated from each other. Compared to 2D TOF images, the stair step artifacts are strongly reduced in reformatted hTOF images, whereas measurement time is decreased by at least 35%. Compared to 3D TOF, the hTOF offers a higher blood‐to‐background contrast, better visualization of smaller vessels, and reduced measurement time.ConclusionThe hTOF benefits from a 2D acquisition and a 3D reconstruction, which makes it a promising technique for the noncontrast‐enhanced imaging of the carotid.