bluuebunny/crossref_metadata_2025_split huggingface dataset:
L’écriture du corps dans l’œuvre d’Alain Bernard Marchand
Authors: Labrosse Claudia 
Published: June 2019

Dans l’œuvre d’Alain Bernard Marchand, le corps des personnages et narrateurs ne s’inscrit pas dans la trame narrative par le seul recours à la représentation traditionnelle. Le corps, à l’origine de toute expérience humaine, s’inscrit aussi au cœur même de l’écriture qu’il enrobe de sa chair. Ainsi, à la lumière de notre analyse du mode de construction du corps romanesque chez Marchand, il apparaît que ce dernier occupe à la fois la position d’objet et de sujet de l’écriture, ce qui permet de parler ici d’une « écriture du corps ».AbstractIn Alain Bernard Marchand’s novels, the bodies of the characters and narrators are integrated into the narrative framework in ways that go beyond traditional representation. The body, the origin of all human experience, lies at the very heart of writing, which is swathed in flesh. In light of our analysis of Marchand’s technique of creating the novelistic body, it appears that the latter is cast as both the object and subject of writing, which we may then call « the writing(s) of the body ».
La nostalgie des origines dans <em>Le Procès-verbal</em> de J.M.G. Le Clézio
Authors: Bachand Denis 
Published: June 2019

Prix Nobel de littérature 2008, le prolifique Jean-Marie Gustave Le Clézio est considéré comme un écrivain majeur dès la parution de son premier roman Le Procès-verbal, pour lequel on lui décernera le Prix Renaudot en 1963. Tout à la fois roman de la régression et de la quête initiatique, Le Procès-verbal préfigure les thématiques qui seront développées par la suite dans l’ensemble de son œuvre. Le présent article en propose une lecture psycho-mythique fondée sur la poétique bachelardienne, la symbolique alchimique et la psychologie jungienne.AbstractProlific author and 2008 Nobel Prize winner in literature, Jean-Marie Gustave Le Clézio was immediately recognized as a major writer with his first novel Le Procès-verbal, for which he received the Prix Renaudot in 1963. In many regards, Le Procès-verbal became a preview of — and reflects — the themes explored and developed in the whole of his future writings. Using Bachelard’s poetic, alchemist symbolism and Jungian psychology as a foundation for interpretation, this article offers a psycho-mythological reading of Le Clézio's first important contribution to literature.
Secret et tension narrative chez Modiano et Le Clézio : entre témoignage et créativité
Authors: Balint-Babos Adina 
Published: June 2019

Les textes de Modiano et de Le Clézio, Dans le café de la jeunesse perdue (2007) et Ritournelle de la faim (2008), placent au centre des récits le secret en tant que fuite. Chez ces deux écrivains, la fuite face aux rafles des juifs dans le Paris de l’Occupation donne à penser les rapports entre témoignage littéraire, faux témoignage et créativité, en posant la question du vécu et de la transfiguration fictionnelle, ainsi qu’une interrogation sur la posture de l’écrivain et les frontières des genres. La figure du déplacement apparaît comme le fil conducteur d’une lecture qui tente de décrypter un pan de la poétique de création modianesque et leclézienne à la croisée de trois dimensions d’interprétation : historique, ontologique et esthétique.AbstractThe narratives of Modiano and Le Clézio, Dans le café de la jeunesse perdue (2007) and Ritournelle de la faim (2008), display secret as taking the flight to save one’s life during the World War II in the Occupation Paris. Representations of Jewish raffles lead us to reflect upon the link between literary testimonials, fake testimonials and creativity as well as upon life and fiction. This also allows us to inquire the figure of the writer and the borders of literary genres. The article attempts to understand the poetics of creation in Modiano and Le Clézio at the crossroads of three dimensions of analysis : historical, ontological and aesthetic.
Intitulé et identité dans les éditions des romans de chevalerie en France (1520-1550)
Authors: Polizzi Gilles 
Published: June 2019

Quelle est la nature de cette métonymie, qui associe les contenus aux titres des livres ? Étiquetage, référentiation ? En prenant pour exemples deux œuvres qu’on tient pour des modèles de déguisement éditorial et fictionnel, le Chevalier Doré (Paris, Janot, 1541) et Girard d’Euphrate (Paris, Longis et Sertenas, 1549), on en fait valoir les convergences inattendues : la conclusion de cette étude montre alors qu’il n’y a pas de rupture véritable dans la transmission des fictions médiévales, mais plutôt un mouvement continu de déformation et d’adaptation du matériau narratif au moment de la Renaissance.AbstractWhat is the exact nature of the metonymy which, for a book, associates a title with specific content/links a title to certain content? Beyond the function of labelling and referencing, the study analyzes two exemplary cases of editorial and narrative disguise: the Chevalier Doré (Paris, Janot, 1541) and Girard d’Euphrate (Paris, Longis et Sertenas, 1549). Unexpectedly related, these cases show that there is indeed no real discontinuity in the transmission of medieval fictions in the Renaissance period, but rather a continuous process of adaptation and transformation.
Doses of Osmocote® in the acclimatization of micropropagated plantlets of Anthurium maricense
Authors: Campos Arlene Santisteban , Do Bomfim Guilherme Vieira , De Azevedo Benito Moreira , Kenji Taniguchi Carlos Alberto , Portugal Pinto de Carvalho Ana Cristina 
Published: June 2019

Anthurium maricense is a tropical ornamental species with great commercial potential in the areas of landscaping and potted foliage plants. One of the main obstacles in the production of micropropagated anthurium plantlets is its slow development and/or the low survival rate of the plantlets during the acclimatization stage. The use of slow-release fertilisers (SRF) can accelerate this process; however, there are no reports in
the literature concerning this practice during acclimatization of micropropagated plantlets of this species. As such, in the present study, the effects of different doses of SRF on the development of micropropagated plantlets of Anthurium maricense were evaluated during the acclimatization stage in a screenhouse. The
experiment was carried out in a completely randomised design, with five treatments and four replications of four plantlets per plot. The treatments comprised doses of 0.0, 2.5, 5.0, 7.5 and 10.0 kg m-3 of the SRF Osmocote® (NPK 15:9:12) added to the substrate. The variables under evaluation were the variation in plant
height, in the number of leaves and in the area of the largest leaf, pot occupancy, net photosynthetic rate, internal carbon, and leaf temperature and moisture. The use of SRF promoted better development of the micropropagated plantlets of A. maricense during the acclimatization stage. Of the variables under analysis,
the variation in the area of the largest leaf is the most important, since the commercial interest of the studied species is the foliage, which was at its maximum with an estimated dose of Osmocote® of 6.40 kg m-3.
COMPARAÇÃO ENTRE TECNOLOGIAS EDUCACIONAIS SOBRE VACINAÇÃO CONTRA PAPILOMAVÍRUS HUMANO EM ADOLESCENTES
Authors: Da Silva Santos Aliniana , Jo Bezerra Sousa George , Lucena Nicodemos Raquel , De Almeida Paulo César , Camelo Chaves Edna Maria , Amaral Viana Maria Corina 
Published: June 2019

<p><strong>Objetivo</strong>: comparar o efeito da aplicação de duas tecnologias educacionais sobre a vacinação contra o papilomavírus humano em adolescentes. <strong>Método: </strong>estudo analítico que comparou duas tecnologias educacionais aplicadas em oito escolas públicas no período de maio a novembro de 2015. Participaram da pesquisa, adolescentes de a 13 anos. Foi aplicado um questionário antes e após a aplicação das Tecnologias Educacionais para avaliação do conhecimento entre grupos (Intervenção e Controle). Os dados foram processados no Statistical Package for the Social Sciences, o efeito foi medido pelos testes t de Student e qui-quadrado. Fixou-se o nível de significância menor ou igual a 0,05. <strong>Resultados</strong>: a Tecnologia Educacional de Enfermagem (p=0,001) teve maior benefício no nível de conhecimento quando comparada à Tecnologia Educacional do Ministério da Saúde (p=0,388). <strong>Conclusão</strong>: a influência positiva da tecnologia educacional de enfermagem sobre a vacinação contra o papilomavírus humano em adolescentes foi evidenciada, e tecnologias dinâmicas tiveram maior efeito na produção do conhecimento.</p>
Acute Presentation of Lumbar Spinal Stenosis Due to Ossified Ligamentum Flavum: The Possible Role of Spondylolisthesis
Authors: Perna Fabrizio , Geraci Giuseppe , Mazzotti Antonio , Stefanini Niccolò , Panciera Alessandro , Faldini Cesare 
Published: June 2019

Case:
A 64-year-old woman with a history of low back pain, presented with acute gait impairment and lower limbs numbness without any history of trauma. Imaging studies revealed ossification of the ligamentum flavum (OLF) at L4-L5 and concomitant spondylolisthesis. Decompression surgery with en-bloc removal including the laminae, the ossified ligamentum flavum, and the medial facet and posterior stabilization was performed resulting in complete immediate recovery.

Conclusions:
This report is the first to describe a case of an acute nontraumatic presentation of OLF associated with spondylolisthesis. OLF pathogenesis in still unknown, although several factors have been considered. According to the literature, operative treatment has demonstrated to be effective.
Lower Extremity Surgical Treatment to Improve Function in a Patient with Gollop-Wolfgang Complex
Authors: Albright Patrick , Veenstra Joshua , Habeck Jason , Bovid Karen 
Published: June 2019

Case:
Gollop-Wolfgang Complex (GWC) includes congenital absence of the tibia with ipsilateral distal femur bifurcation associated with hand/foot ectrodactyly. A 20-month-old male presented with GWC, including left bifid distal femur with ipsilateral tibial hemimelia and absent extensor mechanism, hypoplastic bilateral thumbs, and right foot tarsal-type preaxial polydactyly. Left through-knee amputation preserving growth and contralateral polydactyly reconstruction were performed. Complications of wound infection and dehiscence were successfully treated. Patient is 44 months old and ambulating with left knee disarticulation prosthesis and right supramalleolar orthosis.

Conclusions:
Through-knee amputation and prosthetic fitting provides limb function for GWC patients with tibial hemimelia lacking an extensor mechanism.
Modified Sauve-Kapandji Procedure Using Iliac Bone Graft for Giant Cell Tumor of the Distal Ulna: Stabilizing With Two-Screw Fixation
Authors: Tsai Ting-Chien , Chen Chien-Chin , Huang Hui-Kuang , Wang Jung-Pan 
Published: June 2019

Case:
We describe a 33-year-old man who had a giant cell tumor in the ulnar head treated with wide resection and reconstructed using the modified Sauve-Kapandji procedure with an iliac crest bone graft as ulnar support.

Conclusions:
Due to the destructive nature of the tumor and the important role played by the ulnar head in the distal radioulnar joint (DRUJ), treatment of the giant cell tumor in the distal ulna is a challenge. The modified Sauve-Kapandji procedure is an effective technique to restore DRUJ function, which is performed as an ulnar support arthroplasty. Using an iliac crest bone graft as ulnar support in reconstruction surgery could be a practical method after the ulnar head has been resected.
Pengaruh Daya Motor Bensin Terhadap Kapasitas Produksi Mesin Pemipil Jagung
Authors: Sari Nasmi Herlina , Nurhasanah Nurhasanah 
Published: June 2019

The demand for corn kernels is increasing in developing countries. This study focuses to investigated the effect of power engine on the production capacity of corn sheller machine. The power of engine has been varied i.e 4 HP, 5,5 HP and 8 HP. The methods of this research using by empirisly calculated. The results shows that the maximum production capacity obtained on power engine at 8 HP, 5,5 HP and 4 HP are 14 kg/minutes, 10 kg/min, and 7 kg/min, respectively. The conclusion of this research is the production capacity of corn sheller machine affected by power engine, shaft diameter, pegs length, bearing number and spin sheller.
Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to alterations in gene expression
Authors: Reimer Michael J , Pulakanti Kirthi , Shi Linzheng , Abel Alex , Liang Mingyu , Malarkannan Subramaniam , Rao Sridhar 
Published: June 2019

Abstract
Background: The Tet protein family (Tet1, Tet2, and Tet3) regulate DNA methylation through conversion of 5-methylcytosine to 5-hydroxymethylcytosine which can ultimately result in DNA demethylation and play a critical role during early mammalian development and pluripotency¬. While multiple groups have generated knockouts combining loss of different Tet proteins in murine embryonic stem cells (ESCs), differences in genetic background and approaches has made it difficult to directly compare results and discern the direct mechanism by which Tet proteins regulate the transcriptome. To address this concern, we utilized genomic editing in an isogenic pluripotent background which permitted a quantitative, flow-cytometry based measurement of pluripotency in combination with genome-wide assessment of gene expression and DNA methylation changes. Our ultimate goal was to generate a resource of large-scale datasets to permit hypothesis-generating experiments.
Results: We demonstrate a quantitative disparity in the differentiation ability among Tet protein deletions, with Tet2 single knockout exhibiting the most severe defect, while loss of Tet1 ¬alone or combinations of Tet genes showed a quantitatively intermediate phenotype. Using a combination of transcriptomic and epigenomic approaches we demonstrate an increase in DNA hypermethylation and a divergence of transcriptional profiles in pluripotency among Tet deletions, with loss of Tet2 having the most profound effect in undifferentiated ESCs.
Conclusions: We conclude that loss of Tet2 has the most dramatic effect both on the phenotype of ESCs and the transcriptome compared to other genotypes. While loss of Tet proteins increased DNA hypermethylation, especially in gene promoters, these changes in DNA methylation did not correlate with gene expression changes. Thus, while loss of different Tet proteins alters DNA methylation, this change does not appear to be directly responsible for transcriptome changes. Thus, loss of Tet proteins likely regulates the transcriptome epigenetically both through altering 5mC but also through additional mechanisms. Nonetheless, the transcriptome changes in pluripotent Tet2-/- ESCs compared to wild-type implies that the disparities in differentiation can be partially attributed to baseline alterations in gene expression.
Determination of compound channel apparent shear stress: application of novel data mining models
Authors: Khozani Zohreh Sheikh , Khosravi Khabat , Pham Binh Thai , Kløve Bjørn , Wan Mohtar Wan Hanna Melini , Yaseen Zaher Mundher 
Published: June 2019

AbstractMomentum exchange in the mixing region between the floodplain and the main channel is an essential hydraulic process, particularly for the estimation of discharge. The current study investigated various data mining models to estimate apparent shear stress in a symmetric compound channel with smooth and rough floodplains. The applied predictive models include random forest (RF), random tree (RT), reduced error pruning tree (REPT), M5P, and the distinguished hybrid bagging-M5P model. The models are constructed based on several correlated physical channel characteristic variables to predict the apparent shear stress. A sensitivity analysis is applied to select the best function tuning parameters for each model. Results showed that input with six variables exhibited the best prediction results for RF model while input with four variables produced the best performance for other models. Based on the optimised input variables for each model, the efficiency of five predictive models discussed here was evaluated. It was found that the M5P and hybrid bagging-M5P models with the coefficient of determination (R2) equal to 0.905 and 0.92, respectively, in the testing stage are superior in estimating apparent shear stress in compound channels than other RF, RT and REPT models.
Accelerated Atherosclerosis in Rheumatoid Arthritis: Mechanisms and Treatment
Authors: Reiss Allison B. , Silverman Andrew , Khalfan Muhammed , Vernice Nicholas A. , Kasselman Lora J. , Carsons Steven E. , De Leon Joshua 
Published: June 2019

Background:Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disorder that increases the risk of developing cardiovascular disease. There is accumulating evidence that the RA disease state accelerates the formation of atherosclerotic plaques. Treatments for RA improve joint symptomatology and may reduce inflammation, but consideration of their effects on the cardiovascular system is generally low priority.Objective:Since cardiovascular disease is the leading cause of mortality in RA patients, the impact of RA therapies on atherosclerosis is an area in need of attention and the focus of this review.Results:The drugs used to treat RA may be analgesics, conventional disease-modifying anti-rheumatic drugs, and/or biologics, including antibodies against the cytokine tumor necrosis factor-α. Pain relievers such as nonselective non-steroidal anti-inflammatory drugs and cyclooxygenase inhibitors may adversely affect lipid metabolism and cyclooxygenase inhibitors have been associated with increased adverse cardiovascular events, such as myocardial infarction and stroke. Methotrexate, the anchor disease-modifying anti-rheumatic drug in RA treatment has multiple atheroprotective advantages and is often combined with other therapies. Biologic inhibitors of tumor necrosis factor-α may be beneficial in preventing cardiovascular disease because tumor necrosis factor-α promotes the initiation and progression of atherosclerosis. However, some studies show a worsening of the lipid profile in RA with blockade of this cytokine, leading to higher total cholesterol and triglycerides.Conclusion:Greater understanding of the pharmacologic activity of RA treatments on the atherosclerotic process may lead to improved care, addressing both damages to the joints and heart.
Docking and 3D-QSAR Studies of Hydrazone and Triazole Derivatives for Selective Inhibition of GRK2 over ROCK2
Authors: Keretsu Seketoulie , Bhujbal Swapnil Pandurang , Cho Seung Joo 
Published: June 2019

Introduction:
G protein-coupled receptor kinase 2 (GRK2) is known to be implicated in
heart failure, and therefore serves as an important drug target. GRK2 belongs to the protein kinase A,
G, and C family and shares high sequence similarity with its closely related protein, the Rhoassociated
coiled-coil protein kinase 2 (ROCK2). Therefore, selective inhibition of GRK2 over
ROCK2 is considered crucial for heart failure therapy.

Objective:
To understand the structural factors for enhancing the inhibitory activity for GRK2 and
selectivity over ROCK2, we analyzed and compared molecular interactions using the same set of
ligands against both receptors.

Methods:
We have performed molecular docking and three-dimensional quantitative structure
activity relationship (3D-QSAR) studies on a series of hydrazone and triazole derivatives.

Results:
The presence of hydrophobic substituents at the triazole ring, electronegative substituents
between the pyridine and triazole ring and hydrophobic substituents near the benzene ring increases
the activity of both kinases. Whereas, having non-bulky substituents near the triazole ring, bulky and
hydrophobic substations at the benzene ring and electronegative and H-bond acceptor substituents at
the triazole ring showed a higher inhibitory preference for GRK2 over ROCK2.

Conclusion:
The outcome of this study may be used in the future development of potent GRK2
inhibitors having ROCK2 selectivity.
Factorial Experimental Design for Optimization of Zinc Oxide Nanoparticles Production
Authors: El-Ghwas Dina E. , Mazeed Tarek E. , El-Waseif Amr , Al-Zahrani Hind A. , Almaghrabi Omar A. , Elazzazy Ahmed M. 
Published: June 2019

Background:
Biosynthetic nanomaterials have recently received increasing attention because
they are non-toxic, clean, environmentally acceptable, safe, and biocompatible.

Objective:
In the present study, cell-free culture filtrate of Aspergillus sp. was used for extracellular
synthesis of zinc oxide (ZnO) nanoparticles.

Method:
Plackett-Burman and Taguchi designs were implemented to optimize conditions for maximum
ZnO nanoparticle production. In the Plackett-Burman design, 15 factors, representing different
carbon and nitrogen sources, were studied. For the Taguchi design, an L-27 (313) standard orthogonal
array was constructed to examine nine factors.

Results:
The maximum yield of ZnO nanoparticles of 21.73 g/L was achieved with 1.0 mM ZnSO4
under optimal conditions of peptone extract (20 g/L), yeast extract (10 g/L), meat extract (10 g/L),
K2HPO4 (0.25 g/L), FeSO4⋅7H2O (0.002 g/L), NaCl (2.5 g/L), pH 6, 32°C, and a 200-mL volume.
The ZnO nanoparticles’ production was confirmed by the formation of white aggregates. The UV
absorption spectrum showed one peak at 376 nm, which also confirmed the formation of nanoparticles.
Transmission electron microscopy revealed that the nanoparticles were large rods of 11.6-43.97
nm diameter, and 355.91 nm length. Importantly, the ZnO nanoparticles exhibited broad antimicrobial
activity against gram-positive and gram-negative bacteria and a unicellular fungus.

Conclusion:
The concentrations of ZnSO4 ions, ferrous ions, and peptone and meat extracts, and the
interactions between them, were observed to be the main parameters influencing ZnO nanoparticles’
yield.
Tribology Analysis of Spherical-Surface Contact Sliding Pairs Under Fluctuating Loads
Authors: Yuan Wei , Feng Song , Wang Zhiwen , Guo Qianjian , Yu Jie 
Published: June 2019

Background:
Spherical contacting surfaces are often designed to increase the contact surface
area and bearing ability, and frequently suffer fluctuating loading, which will play an important
role in tribological properties.

Objective:
Effects of high-frequency fluctuating loading on friction and wear performance of spherical-
surface contact sliding pairs should be experimentally investigated.

Methods:
Bench tests with the differential gear contacting pairs of heave trucks were conducted under
fluctuating loading generated by the traction force of spring-connecting hanging weights.

Results:
High amplitude of fluctuating loads tends to result in different wear forms such as fatigue
wear, plowing damages, material side flow and plastic deformation. The amplitude of the fluctuating
loads has significant influence on the tribological performance of the spherical-surface contact sliding
pairs and is apt to break the frictional stability of the friction pairs indicated by the variation of the
signal components of friction force signals decomposed by discrete wavelet transform method.

Conclusion:
The high frequency and large amplitude are the main factors of fluctuating loading that
plays very important role in the tribological characteristics of spherical-surface contact sliding pairs.