bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrical properties as a tool for oil and gas exploration: a case study of Wadi Saal, East Central Sinai, Egypt
Authors: Gomaa Mohamed M 
Published: December 2024

Abstract
Some rock samples (39) have been obtained from Wadi Saal, East Central Sinai, Egypt, for studying electrical, petrographical, and petrophysical parameters. The petrographical analysis shows two major facies. Carbonate (limestone) facies with low porosity (11%) and permeability (69 mD), and sandstone facies with high porosity (28%) and permeability (5901 mD) indicate good reservoir characteristics. Porosity values are related to the bulk density, whereas permeability is controlled by rock porosity and irreducible water saturation. Alternating current (AC) electrical properties were measured with frequency (42 Hz–5 MHz) for samples. Electrical characteristic differences are affected with texture changes, mineralogy, porosity, tortuosity, pore-water salinity, mineral concentrations, permeability, and fluid content. Conductivity and impedance decrease whenever an insulator is existed. The dielectric constant increases with conductor composition (below the percolation) and falls with frequency beyond it. The conductivity expands with the number of conductor pathways connecting the electrodes. The primary objective of this work is to use laboratory AC electrical measurements to shed some light on the relationship between the texture, petrography, petrophysics, and geochemical composition of materials (sandstone and limestone). The goal is to study electrical properties of these mixtures at varying clay concentrations and saturation levels. These analyses could enhance oil and gas recovery by shedding light on reservoir rock electrical characteristics.
Haplotyped genome mapping and functional characterization of a blueberry anthocyanin acetyltransferase (AAT) controlling the accumulation of acylated anthocyanins
Authors: Dare Andrew P , Wu Chen , Carvajal Jose I , Nguyen Han M , Günther Catrin S , Hamiaux Cyril , Bailey Sarah , Deng Cecilia , Mengist Molla F , Iorizzo Massimo , Foster Toshi M , Chagné David , Montanari Sara , Espley Richard V 
Published: December 2024

Abstract
Blueberry has a diversity of anthocyanins that confer its characteristic blue-coloured skin. Whilst most cultivars produce only anthocyanin glycosides, some can add aliphatic or aromatic groups to the sugar moiety to create acylated anthocyanins. Due to their enhanced stability, acylated anthocyanins represent an attractive breeding target in blueberry. In this study, a haplotype-resolved assembly of a previously identified quantitative trait locus on chromosome 2 of ‘Hortblue Petite’ (Vaccinium corymbosum) was created to identify candidate anthocyanin acyltransferase genes. One full-length gene (VcAAT1a) was selected based on quantitative PCR expression profiling and transient expression in tobacco leaves and in strawberry and blueberry fruit flesh. In all three systems, VcAAT1a was able to produce a range of acylated anthocyanins in planta. Recombinant VcAAT1a protein demonstrated that, while VcAAT1a was able to act on both anthocyanin 3-O-glucosides and 3-O-galactosides, it could only utilize acetyl-CoA as an acyl donor. Protein modelling using AlphaFold suggested that this restricted range in acyl donors may be due to a spatially restricted sub-pocket in the acyl-binding site of VvAAT1. Finally, LUC/REN promoter activation assays revealed that the VcAAT1a promoter was transactivated by the VcMYBPA1 and VcMYBPA2 transcription factors, further expanding our knowledge of anthocyanin regulation in blueberry.
Simultaneous radio and X-ray observations of the transitional millisecond pulsar candidate 3FGL J1544.6−1125
Authors: Gusinskaia N V , Jaodand A D , Hessels J W T , Bogdanov S , Deller A T , Miller-Jones J C A , Russell T D , Patruno A , Archibald A M 
Published: December 2024

ABSTRACT
Transitional millisecond pulsars (tMSPs) are neutron star systems that alternate between a rotation-powered radio millisecond pulsar state and an accretion disc-dominated low-mass X-ray binary (LMXB)-like state on multi-year time-scales. During the LMXB-like state, the X-ray emission from tMSPs switches between ‘low’ and ‘high’ X-ray brightness modes on a time-scale of seconds to minutes (or longer), while the radio emission shows variability on time-scales of roughly minutes. Coordinated Very Large Array (VLA) and Chandra observations of the nearby tMSP PSR J1023+0038 uncovered a clear anticorrelation between radio and X-ray luminosities such that the radio emission consistently peaks during the X-ray low modes. In addition, there are sometimes also radio/X-ray flares that show no obvious correlation. In this paper, we present simultaneous radio and X-ray observations of a promising tMSP candidate system, 3FGL J1544.6$-$1125, which shows optical, $\gamma$-ray, and X-ray phenomena similar to PSR J1023+0038, but which is challenging to study because of its greater distance. Using simultaneous VLA and Chandra observations, we find that the radio and X-ray emission are consistent with being anticorrelated in a manner similar to PSR J1023+0038. We discuss how our results help in understanding the origin of bright radio emission from tMSPs. The greater sensitivity of upcoming telescopes such as the Square Kilometre Array will be crucial for studying the correlated radio/X-ray phenomena of tMSP systems.
IFUM integrated field spectroscopy of ten M104 satellite galaxy candidates
Authors: Crosby Ethan , Mateo Mario , Escala Ivanna , Jerjen Helmut , Müller Oliver , Pawlowski Marcel S 
Published: December 2024

ABSTRACT
We report the spectroscopic analysis of 10 satellite galaxy candidates in the sphere of influence of the Sombrero galaxy (M104, NGC4594), based on data obtained with IFUM (integral field units for Magellan). Based on their newly observed recessional velocities, we confirm that nine of these candidates are satellite galaxies of M104, with one being a background dwarf galaxy. All 10 dwarfs have stellar masses $2\times 10^{7}$ to $1\times 10^{9}\, {\rm M}_{\odot }$ and mean weighted metallicities $-1.7\lt \langle {[\mathrm{M/H}]}\rangle \lt -0.3$. Although these dwarfs are predominantly old, with stellar populations $\sim 5{\!-\!}11\,$ Gyr. However, this sample contains a local example of a low-mass ‘green pea’ candidate, it exhibits extreme optical emission features and broad emission line features ($\sigma \sim 250\, \mathrm{km\, s^{-1}}$) reminiscent of high-redshift Ly $\alpha$/Ly C photon leaking galaxies. Using the newly acquired recessional velocities of the nine satellites of M104, we find no evidence of coherent satellite motions unlike other nearby $L_*$ galaxy environments. Given the small sample, this result does not statistically rule out such coherent motions. There remain 60 satellite candidates of M104 for which future spectroscopy can more reliably test for such motion. Using the observed dwarf galaxies as tracers of the gravitational potential of M104, we estimate the dynamical mass of M104, $M_{\rm dyn}=(12.4\pm 6.5)\times 10^{12}\,{\rm M}_{\odot }$, and find that, making a reasonable estimate of M104’s gas mass, $\gt 90$ per cent of its baryons are missing. These results agree with previous measurements of M104’s dynamical mass.
Shock cooling emission from explosions of massive stars – III. Blue supergiants
Authors: Morag Jonathan , Sapir Nir , Waxman Eli 
Published: December 2024

ABSTRACT
Light emission in the first hours and days following core-collapse supernovae is dominated by the escape of photons from the expanding shock-heated envelope. In preceding papers, we provided a simple analytic description of the time-dependent luminosity, L, and colour temperature, $T_{\rm col}$, as well as of the small (${\simeq} 10 {{\, \rm per\, cent}}$) deviations of the spectrum from a blackbody at low frequencies, $h\nu \lt 3T_{\rm col}$, and of ‘line dampening’ at $h\nu \gt 3T_{\rm col}$, for explosions of red supergiants (RSGs) with convective polytropic envelopes (without significant circumstellar medium). Here, we extend our work to provide similar analytic formulae for explosions of blue supergiants with radiative polytropic envelopes. The analytic formulae are calibrated against a large set of spherically symmetric multigroup (frequency-dependent) calculations for a wide range of progenitor parameters (mass, radius, and core/envelope mass ratios) and explosion energies. In these calculations, we use the opacity tables we constructed (and made publicly available), which include the contributions of bound–bound and bound–free transitions. The analytic formulae reproduce the numeric L and $T_{\rm col}$ to within 10 and 5 per cent accuracy, and the spectral energy distribution to within ${\sim} 20\!-\!40 {{\, \rm per\, cent}}$. The accuracy is similar to that achieved for RSG explosions.
The effect of radiation pressure on the dispersal of photoevaporating discs
Authors: Robinson Alfie , Owen James E , Booth Richard A 
Published: December 2024

ABSTRACT
Observed infrared (IR) excesses indicate that protoplanetary discs evolve slowly for the majority of their lifetime before losing their near- and mid-IR excesses on short time-scales. Photoevaporation models can explain this ‘two-time-scale’ nature of disc evolution through the removal of inner regions of discs after a few million years. However, they also predict the existence of a population of non-accreting discs with large cavities. Such discs are scarce within the observed population, suggesting the models are incomplete. We explore whether radiation-pressure-driven outflows are able to remove enough dust to fit observations. We simulate these outflows using cudisc, including dust dynamics, growth/fragmentation, radiative transfer and a parametrization of internal photoevaporation. We find that, in most cases, dust mass-loss rates are around 5–10 times too small to meet observational constraints. Particles are launched from the disc inner rim, however grains larger than around a micron do not escape in the outflow, meaning mass-loss rates are too low for the initial dust masses at gap-opening. Only systems that have smooth photoevaporation profiles with gas mass-loss rates $\gt \sim$$5 \times 10^{-9}$$\mathrm{ M}_\odot$ yr$^{-1}$ and disc dust masses $\lt \sim$1 $\mathrm{ M}_{\oplus }$ at the time of gap opening can meet observational constraints; in the current models these manifest as EUV winds driven by atypically large high-energy photon fluxes. We also find that the height of the disc’s photosphere is controlled by small grains in the outflow as opposed to shadowing from a hot inner rim; the effect of this can be seen in synthetic scattered light observations.
Paradoxical pyoderma gangrenosum secondary to adalimumab successfully treated with methotrexate: A case report
Authors: El Morr Kristy , Rida Mohamad Ali 
Published: December 2024

ABSTRACT
Pyoderma gangrenosum (PG) is a rare inflammatory skin disorder, categorised under neutrophilic dermatoses. It can be idiopathic or associated with underlying conditions like inflammatory bowel disease, autoimmune diseases, and certain cancers. Some medications, including tumour necrosis factor-alpha inhibitors like adalimumab, can also induce this paradoxical reaction. We describe the case of a 19-year-old male with adalimumab-induced PG, which was successfully treated with methotrexate, contributing to the understanding of drug-induced PG and alternative treatment strategies.
Downregulation of MLF1 safeguards cardiomyocytes against senescence-associated chromatin opening
Authors: Lv Jian , Chen Qin , Wang Junmei , Guo Ningning , Fang Yu , Guo Qiuxiao , Li Jiajie , Ma Xiao , Zhan Hongchao , Chen Weihao , Wang Li , Yan Qingqing , Tong Jingjing , Wang Zhihua 
Published: December 2024

Abstract
Aging-associated cardiac hypertrophy (AACH) increases susceptibility to heart failure in the elderly. Chromatin remodeling contributes to the gene reprogramming in AACH; however, the intrinsic regulations remain elusive. We performed a transcriptome analysis for AACH in comparison with pressure-overload-induced pathological cardiac hypertrophy in mice and identified myeloid leukemia factor 1 (MLF1) as an aging-sensitive factor whose expression was reduced during aging but could be reversed by anti-aging administrations. In human AC16 cardiomyocytes, silencing MLF1 suppressed H2O2-induced cell senescence while the phenotype was exacerbated by MLF1 overexpression. RNA-seq analysis revealed that MLF1 functioned as a transcription activator, regulating genomic-clustered genes that mainly involved in inflammation and development. ATAC-seq analysis showed a prominent reduction in chromatin accessibility at the promoter regions of senescence effectors, like IL1B and p21, after MLF1 knockdown. Despite a potential interaction of MLF1 with the histone methyltransferase PRC2, its inhibition failed to reverse the impact of MLF1 knockdown. Instead, MLF1-mediated regulation was blunted by inhibiting the acetyltransferase EP300. CUT&Tag analysis showed that MLF1 bound to target promoters and recruited EP300 to promote H3K27ac deposition. Collectively, we identify MLF1 as a pro-aging epigenetic orchestrator that recruits EP300 to facilitate opening of the condensed chromatin encompassing senescence effectors.
Using paired-end read orientations to assess technical biases in capture Hi-C
Authors: Hansen Peter , Blau Hannah , Hecht Jochen , Karlebach Guy , Krannich Alexander , Steinhaus Robin , Truss Matthias , Robinson Peter N 
Published: December 2024

Abstract
Hi-C and capture Hi-C (CHi-C) both leverage paired-end sequencing of chimeric fragments to gauge the strength of interactions based on the total number of paired-end reads mapped to a common pair of restriction fragments. Mapped paired-end reads can have four relative orientations, depending on the genomic positions and strands of the two reads. We assigned one paired-end read orientation to each of the four possible re-ligations that can occur between two given restriction fragments. In a large hematopoietic cell dataset, we determined the read pair counts of interactions separately for each orientation. Interactions with imbalances in the counts occur much more often than expected by chance for both Hi-C and CHi-C. Based on such imbalances, we identified target restriction fragments enriched at only one instead of both ends. By matching them to the baits used for the experiments, we confirmed our assignment of paired-end read orientations and gained insights that can inform bait design. An analysis of unbaited fragments shows that, beyond bait effects, other known types of technical biases are reflected in count imbalances. Taking advantage of distance-dependent contact frequencies, we assessed the impact of such biases. Our results have the potential to improve the design and interpretation of CHi-C experiments.
TGV: suite of tools to visualize transmission graphs
Authors: Phelan Jody E , Niazi Fatima , Wang Linfeng , Ngwana-Joseph Gabrielle C , Sobkowiak Benjamin , Cohen Ted , Campino Susana , Clark Taane G 
Published: December 2024

Abstract
Graph structures are often used to visualize transmission networks generated using genomic epidemiological methods. However, tools to interactively visualize these graphs do not exist. A browser-based tool allowing users to load and interactively visualize transmission graphs was developed in JavaScript. Associated metadata can be loaded and used to annotate and filter the nodes and edges of transmission networks. The tool is available at jodyphelan.github.io/tgv.
Artificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation With Nicotine Contents and Effects on Product Preference
Authors: Jabba Sairam V , Silinski Peter , Yang Alicia Y , Ouyang Wenyi , Jordt Sven E 
Published: December 2024

Abstract

Introduction
Artificial sweeteners, sucralose and acesulfame-k, are listed as ingredients of oral nicotine pouches (ONPs), a product category with a rapidly growing market share. The exact quantities of these sweeteners in ONPs remain unknown. Artificial sweeteners in ONPs may reduce aversion, facilitate initiation, and encourage consumption behavior.

Aims and Methods
Sucralose and acesulfame-k contents in major US-marketed ONP brands (Zyn, on!, and Velo) were determined by liquid chromatography–mass spectrometry. Sweetener effects on aversion and consumption of ONPs were modeled in single- and two-bottle drinking tests, offering mice ONP extracts calibrated to contain nicotine levels similar to the saliva of people who use smokeless tobacco. To examine the contribution of sweet taste perception, consumption behavior was compared between wild-type and sweet taste receptor-deficient mice (Tas1r2−/−).

Results
Acesulfame-k was detected in on!, Zyn, and Velo ONPs (~0.3 to 0.9 mg/pouch), including products marketed as “Unflavored” or “Flavor ban-approved.” In Velo ONPs, sweetened with sucralose (~0.6 to 1.2 mg/pouch), higher nicotine strength products contained higher sucralose levels. Tas1r2−/− mice consumed less ONP extracts than wild-type mice in both sexes. ONP extracts with both higher nicotine and sweetener strengths were tolerated by wild-type mice, but produced stronger aversion in Tas1r2−/− mice.

Conclusions
ONPs contain significant amounts of artificial sweeteners acesulfame-k and sucralose, with some brands adding more sweeteners to higher nicotine strength ONPs. In mice, artificial sweeteners, at levels present in ONPs, increase nicotine consumption. Increasing sweetener contents facilitates the consumption of higher nicotine strength ONPs. Sweetness imparted by sweetener addition to ONPs likely reduces the aversive sensory effects of nicotine and other ONP constituents.

Implications
Artificial sweeteners such as acesulfame-k or sucralose reduce aversion and likely facilitate the consumption of ONPs. The marketing of some artificially sweetened ONPs as “Unflavored” or “Flavor ban-approved” suggests that the tobacco industry rejects sweet taste as a determinant for the presence of a characterizing flavor. Sweetness as imparted by artificial sweeteners in tobacco products needs to be addressed by regulators as a component of a characterizing flavor, with the aim to reduce product appeal and initiation by never users, and especially youth attracted to sweet flavors.
On learning what to learn: Heterogeneous observations of dynamics and establishing possibly causal relations among them
Authors: Sroczynski David W , Dietrich Felix , Koronaki Eleni D , Talmon Ronen , Coifman Ronald R , Bollt Erik , Kevrekidis Ioannis G 
Published: December 2024

Abstract
Before we attempt to (approximately) learn a function between two sets of observables of a physical process, we must first decide what the inputs and outputs of the desired function are going to be. Here we demonstrate two distinct, data-driven ways of first deciding “the right quantities” to relate through such a function, and then proceeding to learn it. This is accomplished by first processing simultaneous heterogeneous data streams (ensembles of time series) from observations of a physical system: records of multiple observation processes of the system. We determine (i) what subsets of observables are common between the observation processes (and therefore observable from each other, relatable through a function); and (ii) what information is unrelated to these common observables, therefore particular to each observation process, and not contributing to the desired function. Any data-driven technique can subsequently be used to learn the input–output relation—from k-nearest neighbors and Geometric Harmonics to Gaussian Processes and Neural Networks. Two particular “twists” of the approach are discussed. The first has to do with the identifiability of particular quantities of interest from the measurements. We now construct mappings from a single set of observations from one process to entire level sets of measurements of the second process, consistent with this single set. The second attempts to relate our framework to a form of causality: if one of the observation processes measures “now,” while the second observation process measures “in the future,” the function to be learned among what is common across observation processes constitutes a dynamical model for the system evolution.
Perceptual categorization and perceptual concepts
Authors: Green E J 
Published: December 2024

Abstract
Conceptualism is the view that at least some perceptual representation is conceptual. This paper considers a prominent recent argument against Conceptualism due to Ned Block. Block's argument appeals to patterns of color representation in infants, alleging that infants exhibit categorical perception of color while failing to deploy concepts of color categories. Accordingly, the perceptual representation of color categories in infancy must be non-conceptual. This argument is distinctive insofar as it threatens not only the view that all perception is conceptual, but also views that restrict the Conceptualist thesis to perceptual categorization. However, I contend that it fails at two stages. Block's arguments for the perceptual representation of color categories in infancy, and against color concept deployment in infancy, are unpersuasive. Thus, Block has not vanquished Conceptualism. I draw out implications for debates about the perception–cognition border and for the question of whether explicit categorization occurs in perception.
Extension of Λ NN → NNN Weak Interactions and the Two-Nucleon Induced Hypernuclear Nonmesonic Decays: Roles of Strange-Meson and Δ 33-Induced (ρρ)-Pair Exchanges
Authors: Itonaga K , Motoba T , Rijken Th A 
Published: December 2024

Abstract
In the preceding paper we introduced three-body $\Lambda NN \rightarrow NNN$ weak interactions and proposed a framework to deduce the effective two-body $\Lambda N \rightarrow NN$ potentials to be used for estimates of nonmesonic decay rates of hypernuclei. In order to complete the framework, here we extend the treatment to include new diagrams arising from strange-meson exchanges and the $\Delta _{33}$-isobar induced $(\rho \rho )$-pair exchange. Thus we present new forms of the $V^{(\text {eff.2B})}_{(K \pi )\kappa }$, $V^{(\text {eff.2B)}}_{(K \pi )K^{*}}$, and $V^{(\text {eff.2B})}_{D33(\rho \rho )}$ potentials. By adding these potentials to the previous ones, we investigate in full the roles of various types of effective $\Lambda N \rightarrow NN$ potentials in the estimates of two-nucleon induced nonmesonic decays. It is shown that the destructive interference of the tensor forces between the strange-meson-exchange potentials and the non-strange-meson-exchange ones is particularly important in reducing the theoretical two-nucleon induced nonmesonic decay rates. The potential $V^{(\text {eff.2B})}_{D33(\rho \rho )}$ is weak in comparison with $V^{(\text {eff.2B})}_{\rm FM(\pi \pi )}$. The full terms of the potentials have features of strong central, moderately strong, or weak tensors, and weak parity-violating vector forces. Erroneous overestimates of the decay rates reported in the previous paper are corrected, and new numbers calculated with the full terms are presented for the two-nucleon induced decay rates of the $^5_\Lambda {\rm He}$, $^{11}_\Lambda {\rm B}$, and $^{12}_\Lambda {\rm C}$ hypernuclei, which are comparable to the experimental data.