bluuebunny/crossref_metadata_2025_split huggingface dataset:
West Coast ABCs by J. Asnong
Authors: MacLeod Lorisia 
Published: December 2018

Asnong, Jocey. West Coast ABCs. Rocky Mountain Books, 2018.
Jocey Asnong returns with a new ABC book similar to her Rocky Mountain ABCs but this time highlights the beautiful west coast of Canada. Each page of this board book features one or two letters from the alphabet, a west coast place starting with one of those letters, a full colour illustration relating to that place, and a short phrase using words beginning with the alphabet letter(s) of the page. The target audience for this work would include toddlers, pre-K, and early primary students. Some of the words might be difficult for younger readers so this is a book best read with an adult though even the youngest readers will love the bright colours of the illustrations.
Since most of the letters have more than one word, this book better represents some of the different sounds that each letter can make, for example the sounds in paddle versus porpoises which makes this book particularly attractive for anyone working on phonetics with a reader. I would especially recommend this for anyone on the west coast as having familiar places featured in the book would only increase the enjoyment already provided by the wonderful art showcased in this work.
Recommended: 3 stars out of 4 Lorisia MacLeod
Lorisia MacLeod is an Instruction Librarian at NorQuest College Library and a proud member of the James Smith Cree Nation. When not working on indigenization or diversity in librarianship, Lorisia enjoys reading almost any variation of Sherlock Holmes, comics, or travelling.
Experiential Learning: the field study trip, a student-centred curriculum.
Authors: Pattacini Laurence 
Published: December 2018

Drawing from student-centered learning theories, this paper identifies key issues related to active participation of students, collaboration and independent learning. It draws from the author’s experience of developing and delivering a student-centered curriculum delivered around a field study trip. It explores approaches to active and experiential learning in Higher Education through the various stages of the curriculum development and the identification of the pedagogical benefits. The student-centered curriculum is part of a professional accredited course in Landscape architecture. The Field study trip is an opportunity to actively explore the topics of study in real settings and to learn through hands on experience, which is essential to form professionals confronted with making places through planning and design. More generally the field study trip module is an opportunity to understand how to practically embed experiential learning approaches in Higher Education. The paper also discusses the merits of field trip to address some issues related to the learning experience and participation in the context of the internationalisation of the students’ cohort.
Optimization of coagulation-flocculation process in the treatment of wastewater from the brick-manufacturing industry
Authors: Oraeki T. , Skouteris G. , Ouki S. 
Published: December 2018

Abstract
Brick manufacturing is a water-intensive industry that uses water, mainly potable, as a major raw material in its production process. It is therefore imperative that the wastewater generated by this industry is effectively treated for reutilization. There is limited study on how wastewater from the brick-manufacturing industry can be sustainably managed. Hence, this study was conducted to optimize treatment of wastewater generated by the brick manufacturing industry, employing coagulation-flocculation techniques. Commercially available flocculants, namely slightly anionic polyacrylamide (nPAM), anionic polyacrylamide (aPAM), cationic polyacrylamide (cPAM) and poly diallyldimethylammonium chloride (PDADMAC) were screened using the jar test procedure. The one-factor-at-a-time (OFAT) method was used to optimize the process. The nPAM gave optimal performance based on turbidity and suspended solids removal. Results of the evaluations showed an optimal dose of 0.8 mg L−1 at a pH range of 7.2–7.4 and mixing speed of 200 rpm for 5 minutes, followed by 50 rpm for 15 minutes. Both turbidity and total suspended solids removal was approximately 98% at the optimal condition. This study has demonstrated that optimized coagulation-flocculation can produce treated water of high quality that can be reused to reduce mains water consumption and hence contribute to the industry's sustainability.
Computer aid for roof water harvesting systems analysis in rural areas of Mexico
Authors: Sánchez-Cohen Ignacio , Sandoval Aurelio Pedroza , Noyola Samuel Aguilar , Macias-Corral Maritza A. , Velasquez Valle Miguel A. 
Published: December 2018

Abstract
Lack of sufficient good quality water to fulfill the rural population's needs in many countries, such as Mexico, has become one of the main issues governments have to cope with to provide adequate living conditions. The situation has worsened due to rainfall pattern variability influenced by climate change. Water harvesting is an ancient practice that provides an additional water supply for different uses. The lack of sufficient readily available decision tools within these environments has hindered adequate decision-making. The computer aid presented in this paper serves the purpose of a decision tool for use in marginal rural areas where a water harvesting system is to be implemented. Input variables are easily obtained and the system has preloaded information for use in the water balance. The interface is user-friendly, enabling users to plug local information in to obtain outputs on which to base a decision. Input variables can be changed as needed to achieve an acceptable output. The system generates rainfall amounts stochastically enabling posterior analysis to be used in terms of designing roof water harvesting under different runoff occurrence probabilities.
A smart unmanned aerial vehicle (UAV) based imaging system for inspection of deep hazardous tunnels
Authors: Tan C. H. , Ng M. , Shaiful D. S. B. , Win S. K. H. , Ang W. J. , Yeung S. K. , Lim H. B. , Do M. N. , Foong S. 
Published: December 2018

Abstract
Inspection of deep tunnel networks is extremely challenging due to their inaccessibility, and them being an unknown and potentially hazardous environment. Unmanned aerial vehicles (UAVs) provide a viable alternative for access, and are unaffected by debris or sewer flow. However, commercial UAVs are designed for high altitude aerial imagery and are not appropriate for short-range detailed imaging of tunnel surfaces. In addition, autonomous flight is usually achieved using GPS, which is not available underground. This paper presents the design and development of a smart UAV platform, Surveyor with Intelligent Rotating Lens (SWIRL), customized for autonomous operation in tunnels. It can capture high resolution images for subsequent image processing, and defect detection and classification. An innovative rotating system enables undistorted imaging of the tunnel's inner circumference surface using a single camera. The proposed location method using limited data resulted in substantial unit weight and power consumption reductions, compared to existing systems, making more than 35 minutes of autonomous flight possible.
Protective Effect of Selenium-L-methionine on Radiation-induced Acute Pneumonitis and Lung Fibrosis in Rat
Authors: Amini Peyman , Kolivand Sedighe , Saffar Hana , Rezapoor Saeed , Motevaseli Elahe , Najafi Masoud , Nouruzi Farzad , Shabeeb Dheyauldeen , Musa Ahmed Eleojo 
Published: December 2018

Background:
In this study, we aimed to detect the changes in the level of interleukin
(IL)-4 and IL-13 cytokines and their downstream genes including interleukin-13 receptor subunit
alpha-2 (IL13Ra2), interleukin-4 receptor subunit alpha-1 (IL4Ra1), dual oxidase 1 (DUOX1) and
dual oxidase 2 (DUOX2). The protective effects of Selenium-L-methionine on radiation-induced
histopathological damages and changes in the level of these cytokines and genes were detected.

Methods:
Four groups of 20 rats (5 rats in each) namely, control; Selenium-L-methionine, radiation
and radiation plus Selenium-L-methionine were used in this study. 4 mg/kg of Selenium-Lmethionine
was administered 1 day before irradiation and five consecutive days after irradiation.
Irradiation was done using a dose of 15 Gy 60Co gamma rays at 109 cGy/min. All rats were sacrificed
10 weeks after irradiation for detecting changes in IL-4 and IL-13 cytokines, the expressions
of IL13Ra2, IL4Ra1, Duox1 and Duox2 and histopathological changes.

Results:
The level of IL-4 but not IL-13 increased after irradiation. This was associated with increased
expression of IL4Ra1, Duox1 and Duox2, in addition to changes in morphological properties.
Selenium-L-methionine could attenuate all injury markers following lung irradiation.

Conclusion:
Selenium-L-methionine can protect lung tissues against toxic effects of ionizing radiation.
It is possible that the modulation of immune responses and redox interactions are involved in
the radioprotective effect of this agent.
Patents on Quantitative Susceptibility Mapping (QSM) of Tissue Magnetism
Authors: Lin Feng , Prince Martin R. , Spincemaille Pascal , Wang Yi 
Published: December 2018

<P>Background: Quantitative susceptibility mapping (QSM) depicts biodistributions of tissue magnetic susceptibility sources, including endogenous iron and calcifications, as well as exogenous paramagnetic contrast agents and probes. When comparing QSM with simple susceptibility weighted MRI, QSM eliminates blooming artifacts and shows reproducible tissue susceptibility maps independent of field strength and scanner manufacturer over a broad range of image acquisition parameters. For patient care, QSM promises to inform diagnosis, guide surgery, gauge medication, and monitor drug delivery. The Bayesian framework using MRI phase data and structural prior knowledge has made QSM sufficiently robust and accurate for routine clinical practice.Objective:To address the lack of a summary of US patents that is valuable for QSM product development and dissemination into the MRI community.Method:We searched the USPTO Full-Text and Image Database for patents relevant to QSM technology innovation. We analyzed the claims of each patent to characterize the main invented method and we investigated data on clinical utility. </P><P> Results: We identified 17 QSM patents; 13 were implemented clinically, covering various aspects of QSM technology, including the Bayesian framework, background field removal, numerical optimization solver, zero filling, and zero-TE phase.Conclusion:Our patent search identified patents that enable QSM technology for imaging the brain and other tissues. QSM can be applied to study a wide range of diseases including neurological diseases, liver iron disorders, tissue ischemia, and osteoporosis. MRI manufacturers can develop QSM products for more seamless integration into existing MRI scanners to improve medical care.</P>
Effects of Molidustat in the Treatment of Anemia in CKD
Authors: Macdougall Iain C. , Akizawa Tadao , Berns Jeffrey S. , Bernhardt Thomas , Krueger Thilo 
Published: December 2018

Background and objectives
The efficacy and safety of molidustat, a hypoxia-inducible factor-prolyl hydroxylase inhibitor, have been evaluated in three 16-week, phase 2b studies in patients with CKD and anemia who are not on dialysis (DaIly orAL treatment increasing endOGenoUs Erythropoietin [DIALOGUE] 1 and 2) and in those who are on dialysis (DIALOGUE 4).

Design, setting, participants, & measurements
DIALOGUE 1 was a placebo-controlled, fixed-dose trial (25, 50, and 75 mg once daily; 25 and 50 mg twice daily). DIALOGUE 2 and 4 were open-label, variable-dose trials, in which treatment was switched from darbepoetin (DIAGLOGUE 2) or epoetin (DIALOGUE 4) to molidustat or continued with the original agents. Starting molidustat ranged between 25–75 and 25–150 mg daily in DIAGLOGUE 2 and 4, respectively, and could be titrated to maintain hemoglobin levels within predefined target ranges. The primary end point was the change in hemoglobin level between baseline and the mean value from the last 4 weeks of the treatment period.

Results
In DIAGLOGUE 1 (n=121), molidustat treatment was associated with estimated increases in mean hemoglobin levels of 1.4–2.0 g/dl. In DIAGLOGUE 2 (n=124), hemoglobin levels were maintained within the target range after switching to molidustat, with an estimated difference in mean change in hemoglobin levels between molidustat and darbepoetin treatments of up to 0.6 g/dl. In DIAGLOGUE 4 (n=199), hemoglobin levels were maintained within the target range after switching to molidustat 75 and 150 mg, with estimated differences in mean change between molidustat and epoetin treatment of −0.1 and 0.4 g/dl. Molidustat was generally well tolerated, and most adverse events were mild or moderate in severity.

Conclusions
The overall phase 2 efficacy and safety profile of molidustat in patients with CKD and anemia enables the progression of its development into phase 3.
Effects of Dapagliflozin on Circulating Markers of Phosphate Homeostasis
Authors: de Jong Maarten A. , Petrykiv Sergei I. , Laverman Gozewijn D. , van Herwaarden Antonius E. , de Zeeuw Dick , Bakker Stephan J.L. , Heerspink Hiddo J.L. , de Borst Martin H. 
Published: December 2018

Background and objectives
The sodium glucose cotransporter 2 (SGLT-2) inhibitor dapagliflozin is a novel drug for the treatment of diabetes mellitus. Recent studies suggest that SGLT-2 inhibitors affect phosphate homeostasis, but their effects on phosphate-regulating hormones in patients with diabetic kidney disease are still unclear.

Design, setting, participants, & measurements
We performed a post-hoc analysis of a double-blind, randomized, crossover trial in patients with type 2 diabetes with early-stage diabetic kidney disease on stable renin–angiotensin–aldosterone system blockade, with an albumin-to-creatinine ratio between 100 and 3500 mg/g, eGFR≥45 ml/min per 1.73 m2, and glycosylated hemoglobin≥7.2% and <11.4%. Patients were randomized to dapagliflozin 10 mg/d or placebo during consecutive 6-week study periods, separated by a 6-week wash-out. We investigated effects on circulating phosphate, calcium, parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), 25-hydroxyvitamin D (25[OH]D), and 1,25-dihydroxyvitamin D (1,25[OH]2D) levels.

Results
Thirty-one patients (age 62 years; 23% female) were analyzed. Compared with placebo, dapagliflozin increased serum phosphate by 9% (95% confidence interval, 4% to 15%; P=0.002), PTH increased by 16% (3% to 30%; P=0.01), FGF23 increased by 19% (0.3% to 42%; P=0.05), and serum 1,25(OH)2D decreased by −12% (−25% to 4%; P=0.12). Calcium and 25(OH)D were unaffected. We found no correlation between changes in markers of phosphate homeostasis and changes in eGFR or 24-hour albumin excretion during dapagliflozin treatment.

Conclusions
Dapagliflozin increases serum phosphate, plasma PTH, and FGF23. This effect was independent of concomitant changes in eGFR or 24-hour albumin excretion.
APLIKASI TEKNIK DEMULSIFIKASI PEMBENTUKAN KRIM DALAM PEMURNIAN MDAG YANG DIPRODUKSI SECARA GLISEROLISIS
Authors: Mursalin Mursalin , Lavlinesia Lavlinesia , Yernisa Yernisa 
Published: December 2018

Teknik pemisahan residu gliserol dari MDAG yang diproduksi dengan cara gliserolisis paling efektif adalah dengan menggunakan Short Path Distillation (SPD) atau distilasi molekuler yang masih merupakan teknologi mahal dan canggih sehingga sulit untuk diaplikasikan secara luas. Ekstraksi dan fraksinasi menggunakan pelarut merupakan teknik pemisahan residu gliserol yang lain, teknik ini telah dikembangkan oleh beberapa peneliti, tetapi panjangnya prosedur pengerjaan dan adanya kemungkinan sisa pelarut dalam produk akhir menjadi kendala tersendiri. Penelitian ini mempelajari pemisahan residu gliserol dari MDAG hasil proses gliserolisis melalui proses demulsifikasi pembentukan krim dengan atau tanpa penambahan larutan pada berbagai suhu minyak sehingga terbentuk krim dan skim yang mudah dipisahkan. Hasil penelitian menunjukan bahwa pemisahan gliserol dari sistem emulsinya, dengan metode demulsifikasi pembentukan krim paling efektif jika dilakukan pada suhu tinggi (65oC) karena pada suhu tersebut minyak memiliki densitas yang paling rendah dan akan berada pada bagian atas dalam reaktor pemisah residu gliserol saat sistem emulsinya mengalami instabilitas (creaming) sehingga lebih mudah dipisahkan. Pemurnian MDAG dengan cara demulsifikasi pembentukan krim tanpa penambahan air hanya mampu menurunkan kandungan gliserol maksimal sebesar 37%; sisa gliserol yang masih berada dalam produk akhir sekitar 9.17% dirasakan masih terlalu tinggi untuk dapat dikatakan sebagai MDAG murni. Pemurnian dengan cara demulsifikasi pembentukan krim dengan penambahan air suling menghasilkan MDAG dengan kandungan gliserol berkisar aintara 4.05—6.59%. Pemurnian dengan cara demulsifikasi pembentukan krim dengan penambahan larutan elektrolit menghasilkan MDAG dengan kandungan gliserol berkisar antara 1.94—1.95% (tanpa proses sentrifugasi) dan 0.02-0.05% (dengan sentrifugasi 2000 rpm selama 5 menit).
COMPLIANCE WITH IFRS REQUIRED DISCLOSURE AND ANALYSTS’ FORECAST ERRORS: EVIDENCE FROM BRAZIL
Authors: Santos Edilene Santana , Silva Flávia Almeida Morato da , Sheng Hsia Hua , Lora Mayra Ivanoff 
Published: December 2018

We analyze the relationship between analysts' earnings forecast errors and Brazilian listed firms’ compliance with International Financial Reporting Standards (IFRS) required disclosure. Through analysis of a panel data, we examine whether the variance in the Brazilian firms’ disclosure compliance levels in the Notes to Financial Statements for 2010 and 2012 affects analysts’ earnings forecast errors for 2011 and 2013, respectively, finding a significant negative relationship between these variables. By performing a compliance level analysis per firm, our study considers whether and to what extent firms effectively disclose as required by IFRS (as “IFRS serious adopters”), distinguishing them from firms that mere formally adopt IFRS (as “IFRS label adopters”), without effectively complying with it. Following other studies, we use four alternative models to measure the disclosure compliance level per firm, and we do not find significant improvement in the firms’ disclosure levels from 2010 to 2012, except if we use the most tolerant model. By this approach, our research contributes to clarify the impact of IFRS adoption on analysts’ forecast accuracy, as other studies that use only binary variables (analysts’ forecasts before and after IFRS adoption) have found contradictory results. Our findings confirm other studies on the international accounting convergence in other countries, emphasizing that compliance is at least as important as the simply formal IFRS adoption. This corroborates the relevance of enforcement mechanisms to induce firms to better comply with IFRS, thus to better attain the economic benefits expected from its adoption.
Does Audit Firm Tenure Matter to Audit Committee Members? Evidence from an Accounting Dispute
Authors: Rummell Janice E. , DeZoort F. Todd , Hermanson Dana R. 
Published: December 2018

SYNOPSIS
This study examines the effects of Big 4 audit firm tenure on audit committee member support for the auditor in an auditor/management dispute over a subjective accounting issue. One hundred eighteen U.S. public company audit committee members participated in an experiment with audit firm tenure (short/long) manipulated randomly between subjects. The results indicate that participants in the long audit firm tenure group provide more support for the auditor in the dispute than participants in the short tenure group. Audit committee support for the auditor is positively related to audit committee member experience and CPA status, as well as perceived management pressure to meet analyst expectations, but negatively related to perceived management experience in financial reporting. Finally, audit committee members' perceptions of audit firm reliability (i.e., credibility and dependability) mediate the audit firm tenure-auditor support relation. Overall, our results suggest enhanced audit committee support for longer-tenured auditors.
Pasteur nos Livros Didáticos de Biologia do Ensino Médio aprovados no PNLD: uma análise histórica sobre a abordagem da origem da vida e o metabolismo
Authors: Crudeli Ricardo Brasil , Viana Helio Elael Bonini 
Published: December 2018

ResumoEste artigo dedica-se a investigar abordagem de dois dos trabalhos de Louis Pasteur – a geração espontânea e a fermentação – nos livros didáticos (LDs) de Biologia aprovados pelo Plano Nacional do Livro Didático (PNLD), focando nos capítulos que abordam a origem da vida e o metabolismo. Para tanto, estes livros foram analisados qualitativamente (confrontando a abordagem desses LDs com fontes primárias e secundárias) e quantitativamente (seguindo a metodologia estabelecida por Leite, contemplando as “visões deformadas da Ciência” delineadas por Cachapuz). Nesse contexto, foi verificado que os LDs analisados associam, de forma inadequada, o químico Louis Pasteur (1822-1895) a um cientista que refutou a teoria da geração espontânea e sequer mencionam sua participação para a construção das ideias sobre a fermentação. Estes resultados caminham na contramão de estudos de casos históricos realizados sobre o tema, os quais nos mostram que a posição de Pasteur no episódio da geração espontânea está diretamente relacionada aos seus estudos anteriores sobre fermentação, envolvendo os seus posicionamentos político, social e religioso.Palavras-chave: Louis Pasteur; geração espontânea; fermentação; livro didático.AbstractThis article is dedicated to investigate the approach of two works made by Louis Pasteur - in didatic books os Biology approved by the National Plane of Didatic Books (PNLD), focusing in the chapters that discuss the origin of life and metabolism. Therefore, these books were analized qualitatively (dealing the approach of these books with primary and secundary sources) and quantitatively (following the methodology presented in Leite, contemplating the “deformed visions of Science” outlined by Cachapuz). In this context, it was verified that the LDs analyzed associate the chemist Louis Pasteur (1822-1895) with a scientist who refuted the theory of spontaneous generation and did not even mention his participation in the construction of ideas about fermentation. These results are in contrast to historical case studies on the subject, which show us that Pasteur's position in the episode of spontaneous generation is directly related to his previous studies on fermentation, involving his political, social and religious positions. Keywords: Louis Pasteur; spontaneous generation; fermentation; textbook.
Familia y trabajo rural en la Argentina contemporánea: una mirada desde Concepción del Uruguay
Authors: Bergara Rogelio 
Published: December 2018

El presente trabajo tiene como objetivo principal reconstruir parte de la cotidianeidad laboral y social del denominado “mundo chacarero” a partir del estudio de caso del matrimonio Bergara-Marín y sus hijos e hijas en el tiempo que desarrollaron actividades productivas en carácter de “colonos-arrendatarios” en la estancia Centella, situada en el Departamento de Uruguay; en la provincia de Entre Ríos. El marco temporal se extiende desde principios de la década de 1930 hasta el año 1968.
El trabajo de alambrador, las cosechas, la producción familiar, la crianza de animales domésticos, la mantención del hogar y el proceso de urbanización familiar son el cuerpo fundamental del trabajo en cuanto a la reafirmación de identidades y lazos familiares que permiten la reconstrucción de la cotidianeidad del denominado “mundo chacarero”.