bluuebunny/crossref_metadata_2025_split huggingface dataset:
The motivations that define eating patterns in some Mediterranean countries
Authors: Guiné Raquel , Ferrão Ana Cristina , Ferreira Manuela , Correia Paula , Cardoso Ana Paula , Duarte João , Rumbak Ivana , Shehata Abdel-Moneim , Vittadini Elena , Papageorgiou Maria 
Published: April 2019

Purpose
This study to investigate several issues related to food choice and consumption patterns in different countries, including health-related factors; economic and availability aspects; emotional determinants; social, cultural and religious influences; marketing and advertising campaigns; and finally environmental concerns.

Design/methodology/approach
The present study was based on a questionnaire that was exclusively prepared for the project, and which was applied to collect data in different countries, in particular Croatia, Egypt, Italy, Greece and Portugal, which are typically associated with the Mediterranean diet (MD).

Findings
The results obtained allowed, in general, to conclude that in all five countries the motivations related to health as well as environment and politics were the more relevant to determine people’s eating habits (scores varying from 0.3 to 0.7). Women were more influenced by eating motivations than men, and people with moderate exercise were more susceptible to health and environmental motivations and less to emotional, social or marketing motivations (p < 0.001 in all cases). It was also observed that people who adopted a special diet were more prone to eating motivations and that the emotional motivations were more pronounced in people with eating disorders (p < 0.001). Finally, people without chronic diseases or allergies were even more influenced by health motivations than those who actually suffered from these health problems (p < 0.001 in both cases).

Originality/value
This work is important because of the multinational coverage, thus allowing to evaluate the most relevant factors that influenced the food choices of the populations around the Mediterranean Sea, sharing the common link to the MD. The study allowed concluding that, in general, the food choices were primarily determined by health factors and also by concerns related to the environment and sustainability as well as by political influences.
Taxonomic and functional diversity of the co‐flowering community differentially affect Cakile edentula pollination at different spatial scales
Authors: Albor Cristopher , García‐Franco José G. , Parra‐Tabla Víctor , Díaz‐Castelazo Cecilia , Arceo‐Gómez Gerardo 
Published: April 2019

Abstract

The number of co‐flowering species, floral density and floral trait diversity can be major determinants of pollinator‐mediated plant–plant interactions in a community. However, evaluation of how each one of these co‐flowering components affects the pollination success of a single focal plant species, and how these effects vary at different spatial scales, is lacking.

Here, we evaluated the effects of functional diversity (flower morphology and colour), taxonomic diversity (reflecting potential sampling effects) and flower density (conspecific and heterospecific), on the pollinator environment (i.e. visitation rate and pollinator diversity) and pollination success (i.e. pollen load size and number of pollen tubes per style) of Cakile edentula (Brassicaceae). We applied structural equation models (SEMs) at the floral‐neighbourhood (plot level) and community‐wide scales to uncover the factors that mediate co‐flowering community effects on C. edentula pollination success.

We found that co‐flowering community effects at the community level are more important than fine‐scale floral‐neighbourhood differences in mediating plant pollination success in our study species. Increasing plant functional diversity decreased pollinator visitation rate but increased the diversity of pollinator functional groups visiting C. edentula flowers. Taxonomic diversity negatively affected pollinator diversity suggesting that other unmeasured floral traits may be relevant or that single‐species effects (sampling effects) may be important. Overall, our results suggest that functional floral trait diversity in a community may be the most important factor influencing pollination success of species in a community. We also found evidence for intra‐ and interspecific pollinator competition mediated by flower density, but none of these effects seemed to have a significant impact on pollination success.

This study is an important step towards understanding the complexity of co‐flowering community effects on the pollination success of individual plant species at multiple spatial scales. This study further reveals the potential importance of plant functional diversity in a community in helping predict competitive and facilitative interactions in co‐flowering communities.

Synthesis. Floral density and taxonomic and functional co‐flowering diversity are important drivers of pollination success in flowering plants. The effects of the co‐flowering diversity on the pollination success of plant species can largely depend on the spatial scale being studied. Only evaluating the outcomes of pollinator‐mediated plant–plant interactions at multiple stages of the pollination process can lead to a complete understanding of their ecological consequences in nature.
A sociology of public responses to hospital change and closure
Authors: Stewart Ellen 
Published: April 2019

AbstractThe “problem” of public resistance to hospital closure is a recurring trope in health policy debates around the world. Recent papers have argued that when it comes to major change to hospitals, “the public” cannot be persuaded by clinical evidence, and that mechanisms of public involvement are ill‐equipped to reconcile opposition with management desire for radical change. This paper presents data from in‐depth qualitative case studies of three hospital change processes in Scotland's National Health Service, including interviews with 44 members of the public. Informed by sociological accounts of both hospitals and publics as heterogeneous, shifting entities, I explore how hospitals play meaningful roles within their communities. I identify community responses to change proposals which go beyond simple opposition, including evading, engaging with and acquiescing to changes. Explicating both hospitals and the publics they serve as complex social phenomena strengthens the case for policy and practice to prioritise dialogic processes of engagement. It also demonstrates the continuing value of careful, empirical research into public perspectives on contentious healthcare issues in the context of everyday life.
Assessing the influence of sample tagging and library preparation on DNA metabarcoding
Authors: Zizka Vera M. A. , Elbrecht Vasco , Macher Jan‐Niklas , Leese Florian 
Published: April 2019

AbstractMetabarcoding is increasingly used to assess species diversity by high‐throughput sequencing where millions of sequences can be generated in parallel and multiple samples can be analysed in one sequencing run. Generating amplified fragments with a unique sequence identifier ('tag') for each sample is crucial, as it allows assigning sequences to the original samples. The tagging through so‐called fusion primers is a fast and cheap alternative to commercially produced ligation‐based kits. However, little is known about potential bias and inconsistencies introduced by the long nucleotide tail attached to those primers, which could lead to deficient reports of community composition in metabarcoding studies. We therefore tested the consistency and taxa detection efficiency of fusion primers in (1) a one‐step and (2) two‐step PCR protocol as well as (3) a commercially manufactured Illumina kit using mock communities of known composition. The Illumina kit delivered the most consistent results and detected the highest number of taxa. However, success of the two‐step PCR approach was only marginally lower compared to the kit with the additional advantage of a much more competitive price per library. While most taxa were also detected with the one‐step PCR approach, the consistency between replicates including read abundance was substantially lower. Our results highlight that method choice depends on the precision needed for analysis as well as on economic considerations and recommend the Illumina kit to obtain most accurate results and the two‐step PCR approach as a much cheaper yet very robust alternative.
The impact of pre‐operative intravenous iron on quality of life after colorectal cancer surgery: outcomes from the intravenous iron in colorectal cancer‐associated anaemia (IVICA) trial
Authors: Keeler B. D. , Dickson E. A. , Simpson J. A. , Ng O. , Padmanabhan H. , Brookes M. J. , Acheson A. G. ,   the IVICA Trial Group
Published: April 2019

SummaryAnaemia is associated with a reduction in quality of life, and is common in patients with colorectal cancer . We recently reported the findings of the intravenous iron in colorectal cancer‐associated anaemia (IVICA) trial comparing haemoglobin levels and transfusion requirements following intravenous or oral iron replacement in anaemic colorectal cancer patients undergoing elective surgery. In this follow‐up study, we compared the efficacy of intravenous and oral iron at improving quality of life in this patient group. We conducted a multicentre, open‐label randomised controlled trial. Anaemic colorectal cancer patients were randomly allocated at least two weeks pre‐operatively, to receive either oral (ferrous sulphate) or intravenous (ferric carboxymaltose) iron. We assessed haemoglobin and quality of life scores at recruitment, immediately before surgery and at outpatient review approximately three months postoperatively, using the Short Form 36, EuroQoL 5‐dimension 5‐level and Functional Assessment of Cancer Therapy – Anaemia questionnaires. We recruited 116 anaemic patients across seven UK centres (oral iron n = 61 (53%), and intravenous iron n = 55 (47%)). Eleven quality of life components increased by a clinically significant margin in the intravenous iron group between recruitment and surgery compared with one component for oral iron. Median (IQR [range]) visual analogue scores were significantly higher with intravenous iron at a three month outpatient review (oral iron 70, (60–85 [20–95]); intravenous iron 90 (80–90 [50–100]), p = 0.001). The Functional Assessment of Cancer Therapy – Anaemia score comprises of subscales related to cancer, fatigue and non‐fatigue items relevant to anaemia. Median outpatient scores were higher, and hence favourable, for intravenous iron on the Functional Assessment of Cancer Therapy – Anaemia subscale (oral iron 66 (55–72 [23–80]); intravenous iron 71 (66–77 [46–80]); p = 0.002), Functional Assessment of Cancer Therapy – Anaemia trial outcome index (oral iron 108 (90–123 [35–135]); intravenous iron 121 (113–124 [81–135]); p = 0.003) and Functional Assessment of Cancer Therapy – Anaemia total score (oral iron 151 (132–170 [69–183]); intravenous iron 168 (160–174 [125–186]); p = 0.005). These findings indicate that intravenous iron is more efficacious at improving quality of life scores than oral iron in anaemic colorectal cancer patients.
Effect of body position on qualitative and quantitative ultrasound assessment of gastric fluid contents
Authors: Bouvet L. , Barnoud S. , Desgranges F.‐P. , Chassard D. 
Published: April 2019

SummaryWe assessed the impact of raising the upper section of the bed, and patient positioning, on ultrasound assessment of gastric fluid contents. We performed ultrasound examinations in 25 subjects lying on their back, left and right sides at bed angles of 0°, 30°, 45° and 90°; this was carried out while the subjects were fasted, and repeated 10 min after drinking ≥ 50 ml water. After drinking, gastric contents were detected more frequently in the 45° semirecumbent position compared with the supine and 30° positions. The diagnostic performance of the Perlas qualitative grading scale to detect gastric fluid volume > 1.5 ml.kg−1 was improved at 45°, compared with 0° and 30° angles. The use of a composite ultrasound grading scale at a 45° angle was associated with the best performance, with a sensitivity and specificity of 82%. Antral cross‐sectional area was significantly increased when measured in the right lateral position, but there was no effect of raising the bed. In conclusion, raising the upper section of the bed significantly affected qualitative assessment of gastric fluid contents. Further studies are required to determine the most appropriate composite ultrasound grading scale and bed angle for fast and reliable qualitative ultrasound detection of fluid volumes > 1.5 ml.kg−1.
Effects of applying a VR‐based two‐tier test strategy to promote elementary students’ learning performance in a Geology class
Authors: Chang Shao‐Chen , Hsu Ting‐Chia , Kuo Wei‐Chen , Jong Morris Siu‐Yung 
Published: April 2019

AbstractScience and technology are driving people’s life changes, including education and the environment. Many scholars have attempted to import technology into the classroom to help students learn in different subjects. However, students often need assistance with unfamiliar learning approaches and learning environments. This study proposed a non‐immersive virtual reality (VR) guidance system combined with a two‐tier strategy to help students learn geology knowledge. Two groups of students used different learning approaches: the experimental group students were guided by the two‐tier test VR guidance system, and the control group students learned with the conventional VR guidance system. According to the experimental result, the two‐tier test VR guidance system not only improved the students’ learning achievement in natural science, but also enhanced their learning motivation. In addition, according to the sequential results, we found that VR learning materials or environmental resources can help students answer questions and solve problems more effectively.
Random word generation reveals spatial encoding of syllabic word length
Authors: Myachykov Andriy , Chapman Ashley J. , Beal Jack , Scheepers Christoph 
Published: April 2019

Existing random number generation studies demonstrate the presence of an embodied attentional bias in spontaneous number production corresponding to the horizontal Mental Number Line: Larger numbers are produced on right‐hand turns and smaller numbers on left‐hand turns (Loetscher et al.,2008, Curr. Biol., 18, R60). Furthermore, other concepts were also shown to rely on horizontal attentional displacement (Di Bono and Zorzi, 2013, Quart. J. Exp. Psychol., 66, 2348). In two experiments, we used a novel random word generation paradigm combined with two different ways to orient attention in horizontal space: Participants randomly generated words on left and right head turns (Experiment 1) or following left and right key presses (Experiment 2). In both studies, syllabically longer words were generated on right‐hand head turns and following right key strokes. Importantly, variables related to semantic magnitude or cardinality (whether the generated words were plural‐marked, referred to uncountable concepts, or were associated with largeness) were not affected by lateral manipulations. We discuss our data in terms of the ATOM (Walsh, 2015, The Oxford handbook of numerical cognition, 552) which suggests a general magnitude mechanism shared by different conceptual domains.
The Middle Pleistocene glaciolacustrine environment of an ice‐dammed mountain valley, Sudeten Mountains, Poland
Authors: Krzyszkowski Dariusz , Krzywicka Anna , Wachecka‐Kotkowska Lucyna , Sroka Waldemar 
Published: April 2019

This article reports on an Early Saalian proglacial lake formed between the Scandinavian Ice Sheet and the front of the Sudeten Mountains, Poland. Sediments investigated at Mysłów point to a transition from glacifluvial to glaciolacustrine environments. The bulk of the sediments was deposited in deep‐water Gilbert‐type deltas (A–E complexes). A delta plain (topset) gradually passes into a subaerial plateau and then a clastic shoreline and the subaquatic slope of a prograding delta (foreset). The glaciolacustrine lithofacies represent a number of lake‐basin environments, from marginal subaqueous slopes to distal parts of a subaqueous fan. Glaciolacustrine and glaciodeltaic deposits locally reach ˜50–70 m in thickness. Analyses of A–E complexes indicate that the lake existed for more than 130 years and that its origin and evolution were closely connected with the ice front. This case study records lake sedimentation at an ice‐sheet margin with cohesionless gravity flows, turbidity currents, debris‐avalanching and, to a much lesser degree, parapelagic suspension fall‐out and ice‐raft dumping. In the initial stage, the lake extended more than 10 km to the south, and the deposition was relatively slow. In the second stage, recession of the ice sheet caused rapid growth of a delta. The third and ultimate stage coincided with the final glacial recession, with rapid deposition occurring only on the lake bottom. The model of the glaciolacustrine environment presented here may also be applicable to many other proglacial lakes in mountain areas.
Mucosal vaccines and technology
Authors: Miquel-Clopés A , Bentley E G , Stewart J P , Carding S R 
Published: April 2019

Summary
There is an urgent and unmet need to develop effective vaccines to reduce the global burden of infectious disease in both animals and humans, and in particular for the majority of pathogens that infect via mucosal sites. Here we summarise the impediments to developing mucosal vaccines and review the new and emerging technologies aimed at overcoming the lack of effective vaccine delivery systems that is the major obstacle to developing new mucosal vaccines.
Physical home environment is associated with prefrontal cortical thickness in adolescents
Authors: Uy Jessica P. , Goldenberg Diane , Tashjian Sarah M. , Do Kathy T. , Galván Adriana 
Published: April 2019

AbstractBiologically embedded experiences alter developmental trajectories in ways that can influence health, learning, and/or behavior. These systematic differences in experiences may contribute to different biological outcomes as individuals grow and develop, including at the neural level. Previous studies of biologically embedded experiences on neurodevelopment have focused on large‐scale institutional or economic factors (e.g. socioeconomic status [SES]) and psychosocial factors (e.g. caregiving behavior). Less attention has focused on how the quality of the immediate home settings, such as the physical home environment (PHYS), influences neurodevelopment. Moreover, no study has investigated these effects in adolescents, who undergo significant physical maturation and neurodevelopment that may influence how they respond to their physical environments. The goal of the current study was to examine whether PHYS quality is biologically embedded in the developing adolescent brain as evidenced by cognitive achievement and cortical development in 56 (48% female) healthy adolescents (14–18 years (M = 16.83 years, SD = 1.17). Using in‐home assessments of the physical home environment, anatomical brain scans, and indices of academic achievement, we found that adolescents who have more physical problems in the home (e.g. structural hazards, crowding, excessive noise, poorly lit) have thinner prefrontal cortices, which was associated with lower levels of reading achievement, independent of SES and psychosocial factors. By conducting home visits to assess physical characteristics of adolescents’ home, we highlight a typically overlooked aspect of the home environment that has relevance for adolescents’ cognitive and brain development.
ACTIVE (Ability Captured Through Interactive Video Evaluation) workspace volume video game to quantify meaningful change in spinal muscular atrophy
Authors: Alfano Lindsay N , Miller Natalie F , Iammarino Megan A , Moore Clingenpeel Melissa , Lowes Suzanne L , Dugan Margaret E , Kissel John T , Al Zaidy Samiah , Tsao Chang‐Yong , Lowes Linda P 
Published: April 2019

AimTo evaluate the utility of Ability Captured Through Interactive Video Evaluation (ACTIVE) scaled scores to quantify meaningful change in individuals with spinal muscular atrophy (SMA) types 2 or 3 due to disease progression or treatment.MethodACTIVE is a custom‐designed video game that measures workspace volume (WSV). Participants included 62 individuals with SMA (mean age [SD] 10y 9mo [5y], range 2y 9mo–24y) and 362 frequency‐matched controls (mean age [SD] 10y 9mo [3y 6mo], range 3y 2mo–24y 9mo). Participants completed ACTIVE, other traditional assessments, and patient‐reported outcomes. Responsiveness to change was evaluated by comparing longitudinal data on untreated participants to those receiving Spinraza.ResultsACTIVE was significantly correlated to the Hammersmith Functional Motor Scales Expanded and Revised Upper Limb Module (ρ=0.85 and ρ=0.92 respectively; p<0.001). Relevance to patients and families was established by strong correlations to the Patient Reported Outcomes Measurement Information System self‐ and parent proxy‐measures of upper extremity ability (ρ=0.63 and ρ=0.70 respectively; p<0.001). Responsiveness to change was demonstrated by significant change in scaled scores after treatment (median 15.9 points, Wilcoxon signed‐rank test p<0.01). A preliminary minimum clinically important difference is presented.InterpretationThese results suggest that ACTIVE WSV scores are a meaningful assessment with which to quantify change over time in individuals with SMA types 2 and 3.What this paper adds

Ability Captured Through Interactive Video Evaluation (ACTIVE) quantifies upper extremity function in spinal muscular atrophy.

ACTIVE's scaled workspace volume strongly correlates to self‐ and parent‐report of function.

ACTIVE quantifies meaningful change after treatment.