bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Bio‐inspired Cu4O4 Cubane: Effective Molecular Catalysts for Electrocatalytic Water Oxidation in Aqueous Solution
Authors: Jiang Xin , Li Jian , Yang Bing , Wei Xiang‐Zhu , Dong Bo‐Wei , Kao Yi , Huang Mao‐Yong , Tung Chen‐Ho , Wu Li‐Zhu 
Published: April 2018

AbstractInspired by the cubic Mn4CaO5 cluster of natural oxygen‐evolving complex in Photosystem II, tetrametallic molecular water oxidation catalysts, especially M4O4 cubane‐like clusters (M=transition metals), have aroused great interest in developing highly active and robust catalysts for water oxidation. Among these M4O4 clusters, however, copper‐based molecular catalysts are poorly understood. Now, bio‐inspired Cu4O4 cubanes are presented as effective molecular catalysts for electrocatalytic water oxidation in aqueous solution (pH 12). The exceptional catalytic activity is manifested with a turnover frequency (TOF) of 267 s−1 for [(LGly‐Cu)4] at 1.70 V and 105 s−1 for [(LGlu‐Cu)4] at 1.56 V. Electrochemical and spectroscopic study revealed a successive two‐electron transfer process in the Cu4O4 cubanes to form high‐valent CuIII and CuIIIO. intermediates during the catalysis.
Diverse meta‐C−H Functionalization of Arenes across Different Linker Lengths
Authors: Jayarajan Ramasamy , Das Jayabrata , Bag Sukdev , Chowdhury Rajdip , Maiti Debabrata 
Published: April 2018

AbstractArenes containing conformationally flexible long alkyl chains have been successfully functionalized at the meta‐position. Good to excellent meta selectivity is achieved for systems with up to 20 atoms between the target C−H bond and the coordinating heteroatom of the directing group. The palladium‐catalyzed functionalization reactions include alkylation, cyanation, olefination, and acetoxylation. The meta selectivity is exclusively governed by the design of flexible pyrimidine‐based scaffolds.
Stable Copper(I)‐Mediated Base Pairing in DNA
Authors: Jash Biswarup , Müller Jens 
Published: April 2018

AbstractA GNA (glycol nucleic acid) functionalized nucleoside analogue containing the artificial nucleobase 1H‐imidazo[4,5‐f][1,10]phenanthroline (P) was used to form a copper(I)‐mediated base pair within a DNA duplex. The geometrical constraints imposed by the artificial nucleobase play a pivotal role in this unprecedented stabilization of copper(I) in aqueous medium via metal‐mediated base pairing. The formation of the copper(I)‐mediated base pair was investigated by temperature‐dependent UV spectroscopy and CD spectroscopy. The metal‐mediated base pair stabilizes the DNA oligonucleotide duplex by 23 °C. A redox chemistry approach confirmed that this base pair formation was due to the incorporation of copper(I) into the duplex. This first report of a copper(I)‐mediated base pair adds metal‐based diversity to the field and consequently opens up the range of possible applications of metal‐modified nucleic acids.
Low noise ultraviolet photodetector with over 100% enhanced lifetime based on polyfluorene copolymer and ZnO nanoparticles
Authors: Azadinia Mohsen , Fathollahi Mohammadreza , Ameri Mohsen , Shabani Siyavash , Mohajerani Ezeddin 
Published: April 2018

ABSTRACTStability and noise current of a hybrid UV photodetector with inverted planar heterojunction (PHJ) structure indium‐tin‐oxide/ZnO nanoparticles (NPs)/poly[9,9′‐dioctyl‐fluorene‐2,7‐diyl]‐copoly[diphenyl‐p‐tolyl‐amine‐4,4′‐diyl] (BFE)/Ag are investigated. ZnO NPs as the acceptor and BFE as the donor were deposited as the active layer. Under UV light illumination, light to dark current ratio of about 102 is observed at a very low bias voltage of −1.5 V. The spectral response of the device is located near UV region with a maximum responsivity of ∼57 mA/W at wavelength of 350 nm. In particular, the prepared device exhibits remarkably higher photoresponse (∼350%) and stability (∼115%) enhancement under ambient condition compared to the reference device. In addition, the presented results show that the noise current of our device with PHJ structure is about an order of magnitude lower than that of commonly used bulk heterojunction system. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46533.
Synthesis and characterization of a PAMAM dendrimer‐based superplasticizer and its effect on the properties in cementitious system
Authors: Zhao Hongwei , Liao Bing , Nian Fuwei , Zhao Yangyang , Wang Kun , Pang Hao 
Published: April 2018

ABSTRACTIn this work, a polyamidoamine dendrimer‐based polycarboxylic superplasticizer (DPC) with a crosslinked emanative structure was synthesized via simple free radical polymerization. 1H‐nuclear magnetic resonance and Fourier transform infrared spectroscopy measurements were used for structural characterization. The fluidity, rheology behavior, and compressive strength of the cement/DPC samples were investigated in detail. The DPCs performed better dispersion and dispersion maintaining capabilities, stronger water reduction capability, and higher adsorption amounts than the conventional comb‐shaped superplasticizer. The dispersive capacity of the DPC increased with an increasing generation of polyamidoamine dendrimers. Besides, compared with conventional comb‐shaped superplasticizer, the addition of DPC led to a delayed and lowered heat flow peak on the hydration of cement paste at early age of hydration process. Furthermore, compressive strength results showed that the cement/DPC samples performed higher compressive strength than blank cement samples. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46550.
Enhancing Nanos expression via the bacterial TomO protein is a conserved strategy used by the symbiont Wolbachia to fuel germ stem cell maintenance in infected Drosophila females
Authors: Ote Manabu , Yamamoto Daisuke 
Published: April 2018

AbstractThe toxic manipulator of oogenesis (TomO) protein has been identified in the wMel strain of Wolbachia that symbioses with the vinegar fly Drosophila melanogaster, as a protein that affects host reproduction. TomO protects germ stem cells (GSCs) from degeneration, which otherwise occurs in ovaries of host females that are mutant for the gene Sex‐lethal (Sxl). We isolated the TomO homologs from wPip, a Wolbachia strain from the mosquito Culex quinquefasciatus. One of the homologs, TomOwPip1, exerted the GSC rescue activity in fly Sxl mutants when lacking its hydrophobic stretches. The GSC‐rescuing action of the TomOwPip1 variant was ascribable to its abilities to associate with Nanos (nos) mRNA and to enhance Nos protein expression. The analysis of structure–activity relationships with TomO homologs and TomO deletion variants revealed distinct modules in the protein that are each dedicated to different functions, i.e., subcellular localization, nos mRNA binding or Nos expression enhancement. We propose that modular reshuffling is the basis for structural and functional diversification of TomO protein members.
LC–MS/MS method for the simultaneous determination of tenofovir, emtricitabine, elvitegravir and rilpivirine in dried blood spots
Authors: Prathipati Pavan Kumar , Mandal Subhra , Destache Christopher J. 
Published: April 2018

AbstractA simple, short, and rugged LC–MS/MS method for the simultaneous determination of tenofovir, emtricitabine, elvitegravir and rilpivirine was developed and validated. Dried blood spots were prepared with 25 μL of spiked whole blood. A 3 mm punch was extracted with methanol containing labeled internal standards. Ten microliters was injected into the LC–MS/MS using isocratic mobile phase composed of 0.1% formic acid in water and 0.1% formic acid in acetonitrile (45: 55 v/v) at a flow rate of 0.25 mL/min. The method was validated in the range of 10–2000 ng/mL for all four analytes. The intra‐assay accuracy (RE) of the method was −4.73–4.78, 1.35–2.89, −8.89 to −0.49 and − 1.40–1.81 for tenofovir, emtricitabine, elvitegravir and rilpivirine, respectively. The inter‐assay accuracy was within ±15% of nominal and precision (CV) was <15%. The hematocrit effect on quantification was nonsignificant at the tested hematocrit levels (35–70%). The dried blood spot method showed good agreement with the plasma method, and hence can be used as an alternative to plasma method.
Defining the width of the normal tibial plateau relative to the distal femur: Critical normative data for identifying pathologic widening in tibial plateau fractures
Authors: Johannsen Adam m. , Cook Austin M. , Gardner Michael J. , Bishop Julius A. 
Published: April 2018

Tibial plateau widening in the setting of fracture is an indication for surgical treatment, and restoring width is an important goal of surgery. In order to identify and correct pathological widening, the width of the normal tibial plateau must first be defined. The aim of this study was to establish normative data for the width of the tibial plateau relative to the distal femur to enable surgeons to identify and correct pathological widening in the setting of tibial plateau fracture. Fifty‐one uninjured anteroposterior (AP) knee radiographs and 11 XR and CT scans of lateral tibial plateau fractures were retrospectively reviewed. The distances measured included maximal distal femoral width, femoral articular width, tibial articular width, and lateral plateau widening. On average, lateral plateau widening was +0.02 ± 2.03 mm, indicating that the most lateral aspect of the tibial plateau is collinear with the most lateral aspect of the lateral epicondyle of the femur. In the fracture population, average widening was 7.13 ± 3.59 mm on XR and 6.57 ± 3.34 mm on CT, with an absolute difference between XR and CT of 1.19 ± 0.66 mm. In conclusion, this study is the first to define the radiographic anatomy of the proximal tibia quantitatively. In the setting of tibial plateau fracture, residual widening of 2.1 mm could be within normal variation. However, the authors consider widening >2.1 mm pathological. These values can be used for assessing pathological widening of tibial plateau fractures. Clin. Anat. 31:688–692, 2018. © 2018 Wiley Periodicals, Inc.
Examining the role of two aspects of eWOM in online repurchase intention: An integrated trust–loyalty perspective
Authors: Bulut Zeki Atıl , Karabulut Ali Naci 
Published: April 2018

AbstractAs electronic word‐of‐mouth (eWOM) has become an influential information resource for digital consumers who purchase products, understanding how the 2 ways of eWOM influence consumers' online repurchase intention (ORPI) becomes very pivotal. Despite its importance, there is no study in the literature that examined receiving and participating aspects of eWOM in an integrated perspective. The purpose of this study is to understand how 2 controversial eWOM aspects influence ORPI of consumers. Moreover, this study examines the mediating roles of e‐trust and e‐loyalty in the association between 2 sides of eWOM aspects and ORPI. The results indicated that 2 eWOM receiving factors, eWOM quality and eWOM quantity, have positive influences on e‐trust and ORPI. However, as an eWOM participating factor, the eWOM content has no significant influence on ORPI whereas another participating factor, the eWOM intensity, has the greatest impact on ORPI. Furthermore, the findings illustrate that e‐trust has a complementary mediation effect in the association between 2 receiving eWOM aspects and ORPI; likewise, e‐loyalty has a complementary mediation in the relationship between 2 participating eWOM aspects and ORPI.
Oxygen Reduction Reaction Activity of Thermally Tailored Nitrogen‐Doped Carbon Electrocatalysts Prepared through Plasma Synthesis
Authors: Li Oi Lun , Wada Yuta , Kaneko Amane , Lee Hoonseung , Ishizaki Takahiro 
Published: April 2018

AbstractAlthough nitrogen‐doped carbon catalysts are promising candidates for oxygen reduction reactions (ORRs), the role of the nitrogen bonding structure, such as pyridinic‐N, amino‐N, and graphitic‐N, on the ORR activity remains controversial. Furthermore, despite recent progress in tuning the C−N chemical bonding states within the carbon materials by using chemical vapor deposition and post heat treatment, a systematic evaluation of various N moieties remains challenging, owing to the differences in the thermal stabilities of different types of bonds. Herein, we successfully designed a method to tailor pyridinic‐N, amino‐N, and graphitic‐N bonding in N‐doped carbon nanoparticles fabricated through a plasma process combined with post heat treatment. Investigations on the electrochemical performance of the fabricated materials suggested that catalysts with dominant amino‐N exhibited higher current density, where graphitic‐N has a positive effect on the ORR onset potential. This synthetic strategy provides a simple and efficient approach for studying the relationship between the C−N bonding structure and the electrochemical performance of N‐doped carbon catalysts.
BN‐Patterning of Metallic Substrates through Metal Coordination of Decoupled Borazines
Authors: Schwarz Martin , Garnica Manuela , Fasano Francesco , Demitri Nicola , Bonifazi Davide , Auwärter Willi 
Published: April 2018

AbstractWe report on the synthesis of pyridine‐terminated borazine derivatives, their molecular self‐assembly as well as the electronic properties investigated on silver and copper surfaces by means of scanning tunneling microscopy and X‐ray photoelectron spectroscopy. The introduction of pyridine functionalities allows us to achieve distinct supramolecular architectures with control of the interdigitation of the molecules by surface templating. On silver surfaces, the borazine derivatives arrange in a dense‐packed hexagonal structure through van der Waals and H‐bonding interactions, whereas on Cu(111), the molecules undergo metal coordination. The porosity and coordination symmetry of the reticulated structure depends on the stoichiometric ratio between copper adatoms and the borazine ligands, permitting an unusual three‐fold coordinated Cu–pyridyl network. Finally, spectroscopy measurements indicate that the borazine core is electronically decoupled from the metallic substrate. We thus demonstrate that BNC‐containing molecular units can be integrated into stable metal‐coordination architectures on surfaces, opening pathways to patterned, BN‐doped sheets with specific functionalities, for example, regarding the adsorption of polar guest gases.
Divergent Elementoboration: 1,3‐Haloboration versus 1,1‐Carboboration of Propargyl Esters
Authors: Wilkins Lewis C. , Soltani Yashar , Lawson James R. , Slater Ben , Melen Rebecca L. 
Published: April 2018

AbstractThis work showcases the 1,3‐haloboration reaction of alkynes in which boron and chlorine add to propargyl systems in a proposed sequential oxazoliumborate formation with subsequent ring‐opening and chloride migration. In addition, the functionalization of these propargyl esters with dimethyl groups in the propargylic position leads to stark differences in reactivity whereby a formal 1,1‐carboboration prevails to give the 2,2‐dichloro‐3,4‐dihydrodioxaborinine products as an intramolecular chelate. Density functional theory calculations are used to rationalize the distinct carboboration and haloboration pathways. Significantly, this method represents a metal‐free route to highly functionalized compounds in a single step to give structurally complex products.
Involving Synergy of Green Light and Acidic Responses in Control of Unimolecular Multicolor Luminescence
Authors: Zhou Yunyun , Zhu Liangliang 
Published: April 2018

AbstractConversion of multicolor luminescence is one of desirable goals in study and development of next‐generation molecular emitters, whereas involving visible light into the control of the above‐mentioned ability has been poorly addressed due to the need of a relatively complicate molecular design. In this work, we present a novel dyad with a linkage of 4‐piperazinyl‐1,8‐naphthalimide and cyanostyryl‐modified azulene moiety, upon which the luminescence signal can be orthogonally controlled by protonation and green light irradiation. The superior features of the protonation induced excited state energy alteration, followed by green light driven photoisomerization led to a progressive luminescent color conversion among blue, yellow and green at the single molecular level. This strategy may bring in novel insights for preparing advanced function‐integrated optoelectronic materials.
Crystallization of a Novel Germanosilicate ECNU‐16 Provides Insights into the Space‐Filling Effect on Zeolite Crystal Symmetry
Authors: Xu Le , Zhang Lin , Li Jian , Muraoka Koki , Peng Fei , Xu Hao , Lin Cong , Gao Zihao , Jiang Jin‐Gang , Chaikittisilp Watcharop , Sun Junliang , Okubo Tatsuya , Wu Peng 
Published: April 2018

AbstractSynthesis of new zeolites involving organic molecules relies heavily on the trial‐and‐error approach, because it is difficult to interpret the determining effects of organics on zeolite crystal symmetry. Here, the intrinsic relationships among the space‐filling of organics, included volume of channels, and zeolite crystal symmetry, are systematically demonstrated by experimental and computational means. Under controlled conditions, the “dimer” and “monomer” organics of 1‐ethyl‐3‐methylimidazolium selectively direct different, but related, germanosilicates, the ECNU‐16 with a new topology and the existing IM‐16 with the UOS topology, respectively. The comprehensive computational study reveals that the zeolite phase selectivity is determined by the unique space‐filling behavior of the “dimer” and “monomer” organics, which is closely correlated to their rotation freedom, as well as the included volume of host zeolite channels. The elucidation of this crucial space‐filling effect from the fundamental viewpoint will provide new guidelines for the rational design and synthesis of new zeolites in future.
Acrodermatitis continua of Hallopeau successfully treated only with infliximab: A case report
Authors: Kioka Mana , Yu Akitoshi , Tanizaki Hideaki , Kokunai Yasuhito , Kurokawa Teruo , Moriwaki Shinichi 
Published: April 2018

AbstractA 22‐year‐old man presented with a 2‐month history of rapidly progressing pustular eruptions on the accrual regions of his fingers and toes with local arthralgia and severe nail destruction. A histological examination revealed parakeratosis, hyperkeratosis and elongation of the rete ridges of the epidermis with exocytosis of neutrophils forming spongiform pustules of Kogoj. Based on these findings, we diagnosed this case as acrodermatitis continua of Hallopeau (ACH). ACH, a variant of pustular psoriasis, is often resistant to various topical treatments, and the patient experienced prominent decline in his quality of life. Therefore, we decided to use infliximab in the present case. After the fourth administration of infliximab alone, the patient's digital arthralgia and pustular eruptions disappeared completely, and the long‐term administration of infliximab drastically reduced all of the patient's symptoms of ACH, including the nail lesions without any adverse events or recurrence. Our findings suggest that ACH shares a disease spectrum with plaque‐type and pustular psoriasis. In addition, biologic agents such as a tumor necrosis factor‐α inhibitor are useful for treating patients with ACH just as those with psoriasis and may even be used alone.
Facile Synthesis of Palladium‐Nanoparticle‐Embedded N‐Doped Carbon Fibers for Electrochemical Sensing
Authors: Shim Kyubin , Wang Zhong‐Li , Mou Tasnima Haque , Bando Yoshio , Alshehri Abdulmohsen Ali , Kim Jeonghun , Hossain Md. Shahriar A. , Yamauchi Yusuke , Kim Jung Ho 
Published: April 2018

AbstractIn recent years, there have been many studies on metal/carbon hybrid materials for electrochemical applications. However, reducing the metal content in catalysts is still a challenge. Here, a facile synthesis of palladium (Pd) nanoparticle‐embedded N‐doped carbon fibers (Pd/N‐C) through electropolymerization and reduction methods is demonstrated. The as‐prepared Pd/N‐C contains only 1.5 wt % Pd. Under optimal conditions, bisphenol A is detected by using amperometry in two dynamic ranges from 0.1 to 10 μm and from 10 to 200 μm, and the obtained correlation coefficients are close to 0.9836 and 0.9987, respectively. The detection limit (DL) for bisphenol A is determined to be 29.44 (±0.77) nm.
Construction of Bifunctional Co/H‐ZSM‐5 Catalysts for the Hydrodeoxygenation of Stearic Acid to Diesel‐Range Alkanes
Authors: Wu Guangjun , Zhang Nan , Dai Weili , Guan Naijia , Li Landong 
Published: April 2018

AbstractBifunctional Co/H‐ZSM‐5 zeolites were prepared by a surface organometallic chemistry grafting route, namely, by the stoichiometric reaction between cobaltocene and the Brønsted acid sites in zeolites. The catalyst was applied to a model reaction of the catalytic hydrodeoxygenation of stearic acid (SA). The cobalt species existed in the form of isolated Co2+ ions at the exchange positions after grafting, transformed to CoO species on the surface of the zeolite, stabilized inside the zeolite channels upon calcination in air, and finally reduced by hydrogen to homogeneous clusters of metallic cobalt species approximately 1.5 nm in size. During this process, the Brønsted acid sites of the H‐ZSM‐5 zeolites were preserved with a slightly reduced acid strength. The as‐prepared bifunctional catalyst exhibited an approximately 16 times higher activity for the hydrodeoxygenation of SA (2.11 gSA gcat−1 h−1) than the reference catalyst (0.13 gSA gcat−1 h−1) prepared by solid‐state ion exchange and a high C18/C17 ratio of approximately 24. The remarkable hydrodeoxygenation performance of the bifunctional Co/H‐ZSM‐5 was owed to the effective synergy between the uniformed metallic cobalt clusters and the Brønsted acid sites in H‐ZSM‐5. The simplified reaction network and kinetics of the SA hydrodeoxygenation catalyzed by the as‐prepared bifunctional Co/H‐ZSM‐5 zeolites were also investigated.
Discovering cortical sulcal folding patterns in neonates using large‐scale dataset
Authors: Meng Yu , Li Gang , Wang Li , Lin Weili , Gilmore John H , Shen Dinggang 
Published: April 2018

AbstractThe folding of the human cerebral cortex is highly complex and variable across individuals, but certain common major patterns of cortical folding do exist. Mining such common patterns of cortical folding is of great importance in understanding the inter‐individual variability of cortical folding and their relationship with cognitive functions and brain disorders. As primary cortical folds are mainly genetically influenced and are well established at term birth, neonates with minimal exposure to the complicated postnatal environmental influences are ideal candidates for mining the major patterns of cortical folding. In this paper, we propose a sulcal‐pit‐based method to discover the major sulcal patterns of cortical folding. In our method, first, the sulcal pattern is characterized by the spatial distribution of sulcal pits, which are the locally deepest points in cortical sulci. Since deep sulcal pits are genetically related, relatively consistent across individuals, and also stable during brain development, they are well suited for representing and characterizing the sulcal patterns. Then, the similarity between the distributions of sulcal pits is measured from the spatial, geometrical, and topological points of view. Next, a comprehensive similarity matrix is constructed for the whole dataset by adaptively fusing these measurements together, thus capturing both their common and complementary information. Finally, leveraging the similarity matrix, a hierarchical affinity propagation algorithm is used to group similar sulcal folding patterns together. The proposed method has been applied to 677 neonatal brains, and revealed multiple distinct and meaningful sulcal patterns in the central sulcus, superior temporal sulcus, and cingulate sulcus.