bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengontrol Alat Penyiram Taman Otomatis Menggunakan SMS Berbasis Mikrokontroller IC Atmega 16
Authors: Yurindra Yurindra , Sobri Mohammad 
Published: October 2018

Tujuan pembuatan alat ini adalah untuk mengurangi kerepotan user dari penyiram taman secara manual yang banyak menguras tenaga menjadi penyiram taman secara canggih yang tidak menguras tenaga. Alat ini menggunakan password sebagai pengaman dalam alat ini,sehingga user lain yang mau menjalankan alat ini tidak bisa tanpa mengetahui password tersebut. Selain itu alat ini dapat digunakan secara manual. Hal seperti ini memerlukan suatu pemecahan teknologi yang tepat guna. Pengujian sistem keseluruhan ini merupakan uji coba keadaan-keadaan realitas pada saat digunakan. Pengontrol alat menggunakan sms maupun manual harus menggunakan password yang benar serta menggunakan format sms yang benar dan sudah ditentukan,sehingga user dan alat pengontrol dapat berjalan dengan lancar.User dapat mengendalikan alat tersebut kapan saja dan dari mana saja user berada.
Penggunaan Wiper Helm Otomatis Dan Kendali Kelistrikan Motor Berbasis Mikrkontroler Arduino
Authors: Samudra Samudra , Novianto Dian 
Published: October 2018

Pengendara sepeda motor dihadapkan dengan berbagai masalah saat berkendara seperti yang akan saya teliti berikut ini yaitu gangguan cuaca seperti air hujan yang mengenai kaca helm dan gangguan manusia seperti perampasan sepeda motor. Pada alat yang saya buat ini mempunyai dua fungsi yaitu fungsi wiper dan fungsi yang dapat mematikan sepeda motor dari jarak tertentu. Pada fungsi wiper helm digunakan sensor hujan sebagai alat yang mampu menditeksi curah air hujan dan motor servo sebagai penggerak wiper yang di proses oleh arduino Nano. Dan pada fungsi kendali listrik motor dari jarak tertentu terdapat tombol push button sebagai tombol emergency yang terletak pada helm dan di proses oleh arduino uno yang terkoneksi otomatis ke arduino Mega yang terletak pada motor melalui Bluetooth untuk mematikan sepeda motor. Sedangkan untuk menghidupkan motor disediakan keypad pada arduino Mega yang terletak pada motor yang digunakan sebagai tempat mengisi password untuk menghidupkan motor. Pada pengujian yang dilakukan, alat ini dapat mematikan sepeda motor dengan jarak 13 meter dan motor otomatis tidak dapat di hidupkan dan ketika ingin menghidupkan kembali motor tersebut harus dengan menekan mengisi password dengan cara menekan keypad yang berada pada sepeda motor.
Rancangan Sistem Aplikasi E-learning: Studi Kasus SMK Negeri 1 Pangkalpinang
Authors: Febriani Ulfa Sari , Hamidah Hamidah , Rizan Okkita 
Published: October 2018

Teaching and learning process in SMK Negeri 1 Pangkalpinang are still conventional, where the students and teacher activities are only conducted in classroom. Various teaching concepts and techniques have been developed to complement the conventional methods that rely solely on a one-way method of learning andteaching in the classroom. One of teaching methods is currently being developed is e-learning. E-learning is Teachers’aid in distributing their materials where they must not attend in classroom, but use internet access. It is the best way to maximized the studying time in limited rooms.E-learning could help teaching and learning process more efficient. To realize E-learning Application in SMK Negeri 1 Pangkalpinang, it can be carried out by Learning Management System (LMS) design using Moodle. Moodle (Modular Object Oriented Dynamic Learning Environment) is one off the free LMS that can be downloaded, be utilized and be modified with a license as GPU (General Public License). The E-learning website will be used as additional discussion media for discussing unfinished learning materials, and multiple-choice exams and submitted tasks.
Human Papilloma Virus Selftesting as an Alternative Method for Cervical Cancer Screening
Authors: Chandra Richard , Rauf Syahrul , Malinta Umar 
Published: October 2018

Objective: To determine the level of acceptance of self Human Papilloma Virus (HPV) examination and to compare the level of sensitivity and specificity of self HPV examination with Fluid Based Cytology on precancerous cervical lesion and cervical cancer.
Methods: The analytical method used in this research was cross sectional with purposive sampling. This study is conducted at Wahidin Sudirohusodo Hospital and its affiliation from October 2014 to May 2015 with 101 subjects. The data measurement used self HPV examination tool and fluid based cytology kit. The data collected through questionnaires before and after the examination. The laboratory examination was carried out using the way of HPV Genotyping primary system (MY09/11) method Wl LTS-06, which is able to
detect 35 types of HPV viruses.
Results: A total of 101 subjects were involved in this study. The subjects were divided into two groups: the abnormal and normal group (n - 50/51). The acceptance level of self HPV examination was 62.37% (n = 63/101). Majority of subjects (88.21%) were ready to repeat the same examination in the future. The level of sensitivity and specificity for self HPV were (56% (95%CI (41.25 - 70.01%)) vs 98% (95%CI (89.55 - 99.95%)), p=<0.000001, while the level of sensitivity and specificity for fluid based cytology were (40% (95%CI (26.41 - 54.82%)) vs 98% (95%CI (89.35 - 99.95%)), p=0.000002.
Conclusion: HPV self-testing is very potential to be used as an alternative method for cervical cancer screening.
[Indones J Obstet Gynecol 2017; 5-2: 114-119]
Keywords: cervical cancer, cervical cancer screening, human papilloma virus, sensitivity, specificity
The Use of GIS to Draw Literary Maps of Compostela. Applications in the Educational Field
Authors: López-Sández María 
Published: October 2018

For three years now, a research group at the University of Santiago de Compostela has been working on the creation of literary maps of Compostela. 1 In this application of Geographic Information Systems (GIS) to literature, with the focus on a city of remarkable symbolic relevance, problems emerged, mainly concerning the mappeability of uncertainty and the codification of recurrence and emotions. The point of departure was a very precise group of texts belonging to the subgenre of the ‘estudiantina’ that depict the life of Santiago University students at the end of the 19th and the beginning of the 20th century. In this paper, we intend to present the results, showing the achievements, the limits and the new challenges that emerged. Literary cartographies have proved useful for the study of symbolic production and for tourism. Less attention has been paid to its applicability to education, and yet, the tools used so far for creating literary cartographies can be applied to the study of literary texts produced by students, so that the resulting maps and graphics cast important information for the analysis of how students understand and deal with places, how they relate to the cities they live in and, thereby, reveal the constitution of their mental maps. In this paper, we will compare literary maps of Santiago obtained on the one hand from the database created with the ‘Estudiantina’ and, on the other, from the database of 40 texts written by current students. Taking the maps as a point of departure, we will reflect on the historical changes in the imaginary of the city and the way it is perceived, inhabited and lived by current students.
A comparative evaluation of the efficacy of dimethylaminoethanol derivative 7–16, C7070 and picamilon in correction of experimental hypertensive neuroretinopathy
Authors: Peresypkina Anna A. 
Published: October 2018

Introduction. The efficacy of dimethylaminoethanol (DMAE) derivative 7–16, substance C7070 in comparison with picamylon in hypertensive neuroretinopathy model in white laboratory rats was evaluated.
Materials and methods. For measuring the blood pressure, a system of noninvasive blood pressure measurement in small animals NIBP200 was used. Ophthalmoscopy was performed by using Bx a Neitz ophthalmoscope (Japan) and Osher MaxField 78D lens, OI-78M model. Electroretinography (ERG) was recorded in response to a single stimulation. Biopotentials were presented graphically on the screen with the help of BIOPAC SYSTEMS MP-150 with ACQKNOWLEDGE 4.2 software (USA). To assess a degree of a functional retinal disorder, the b/a coefficient was used.
Results and discussion. The most pronounced protective effect on the model of hypertensive neuroretinopathy is demonstrated by C7070, which is expressed in the notable approximation to the normal eye fundus image and reaching the target values of the b/a coefficient. In the group with correction by DMAE derivative 7–16, a protective effect is observed, which exceeds picamilon, which is expressed in the elimination of soft and solid exudates, vein and venule plethora, vascular tortuosity, arterial spasm, Salus-Gunn I symptom, hemorrhages; the b/a increases significantly by 26% compared to the group without correction (p < 0.05).
Conclusion. The eye fundus image and functional state of the retina are completely restored when correcting experimental hypertensive neuroretinopathy with C7070 in a dose of 50 mg/kg to laboratory rats and partially restored when correcting with DMAE derivative 7–16 in a dose of 25 mg/kg, which in both cases exceeds the protective effect of the reference drug picamilon on the model of hypertensive neuroretinopathy.
The Lake CHAd Deep DRILLing project (CHADRILL) – targeting  ∼ 10 million years of environmental and climate change in Africa
Authors: Sylvestre Florence , Schuster Mathieu , Vogel Hendrik , Abdheramane Moussa , Ariztegui Daniel , Salzmann Ulrich , Schwalb Antje , Waldmann Nicolas ,   the ICDP CHADRILL Consortium
Published: October 2018

Abstract. At present, Lake Chad (∼ 13∘′ N, ∼ 14∘ E) is
a shallow freshwater lake located in the Sahel/Sahara region of central
northern Africa. The lake is primarily fed by the Chari–Logone river system
draining a ∼ 600 000 km2 watershed in tropical Africa. Discharge
is strongly controlled by the annual passage of the intertropical convergence
zone (ITCZ) and monsoon circulation leading to a peak in rainfall during
boreal summer. During recent decades, a large number of studies have been
carried out in the Lake Chad Basin (LCB). They have mostly focused on a
patchwork of exposed lake sediments and outcrops once inhabited by early
hominids. A dataset generated from a 673 m long geotechnical borehole
drilled in 1973, along with outcrop and seismic reflection studies, reveal
several hundred metres of Miocene–Pleistocene lacustrine
deposits. CHADRILL aims to recover a sedimentary core spanning the Miocene–Pleistocene
sediment succession of Lake Chad through deep drilling. This record will
provide significant insights into the modulation of orbitally forced changes
in northern African hydroclimate under different climate boundary conditions
such as high CO2 and absence of Northern Hemisphere ice sheets. These
investigations will also help unravel both the age and the origin of the lake
and its current desert surrounding. The LCB is very rich in early hominid
fossils (Australopithecus bahrelghazali; Sahelanthropus tchadensis) of Late Miocene age. Thus, retrieving a sediment core from this
basin will provide the most continuous climatic and environmental record with
which to compare hominid migrations across northern Africa and has major
implications for understanding human evolution. Furthermore, due to its
dramatic and episodically changing water levels and associated depositional
modes, Lake Chad's sediments resemble maybe an analogue for lake systems that
were once present on Mars. Consequently, the study of the subsurface
biosphere contained in these sediments has the potential to shed light on
microbial biodiversity present in this type of depositional environment. We propose to drill a total of ∼ 1800 m of poorly to semi-consolidated
lacustrine, fluvial, and eolian sediments down to bedrock at a single
on-shore site close to the shoreline of present-day Lake Chad. We propose to
locate our drilling operations on-shore close to the site where the
geotechnical Bol borehole (13∘28′ N, 14∘44′ E) was
drilled in 1973. This is for two main reasons: (1) nowhere else in the Chad
Basin do we have such detailed information about the lithologies to be
drilled; and (2) the Bol site is close to the depocentre of the Chad Basin
and therefore likely to provide the stratigraphically most continuous
sequence.
n. 10 - POLÍTICA DE ASSISTÊNCIA ESTUDANTIL: REPERCUSSÕES SOBRE A SUA CONTRIBUIÇÃO
Authors: Macedo Juliana Cavalcanti , Abranches Ana de Fátima Sousa 
Published: October 2018

Esta pesquisa apresenta como elemento principal a relação entre o ensino superior e as políticas públicas educacionais de assistência estudantil. Na tentativa de uma aproximação entre aquilo que é discutido sobre o assunto na literatura especializada, e o que ocorre efetivamente em uma realidade empírica, no âmbito de uma instituição de ensino superior. A pesquisa teve como principal objetivo analisar a política de assistência estudantil da Universidade Federal Rural de Pernambuco (UFRPE), a partir da percepção dos estudantes beneficiados. A importância desta pesquisa está na possibilidade de se discutir a contribuição da assistência estudantil compreendendo-a como parte da política educacional. Quanto à metodologia, a investigação se baseou no método quali-quanti, integrando os enfoques qualitativo e quantitativo, seguindo etapas complementares que visaram contribuir na coleta, análise e interpretação dos dados. Para tanto, realizou-se o levantamento de dados secundários sobre as principais temáticas da pesquisa, e no trabalho de campo, foram aplicados questionários com estudantes beneficiados pela política. Os dados analisados demonstram que a maioria dos estudantes avalia como boa a política de assistência estudantil da UFRPE, assim como, afirma que a assistência estudantil contribui muito para a sua permanência na universidade. Contudo, também revela algumas situações que precisam ser reavaliadas e melhoradas.
n. 17 - 30 ANOS DO PRINCÍPIO DE GESTÃO DEMOCRÁTICA DO ENSINO: O QUE TEMOS PARA CELEBRAR?
Authors: Esquinsani Rosimar Serena Siqueira , Dametto Jarbas 
Published: October 2018

O texto discute o princípio da Gestão Democrática do ensino público, previsto há 30 anos na Constituição Federal de 1988. Entendendo que o princípio da Gestão Democrática tem espaço garantido nos debates e ações de política educacional, seja por sua relevância, natureza multifatorial ou polissemia do termo, propõe-se a discussão desse princípio a partir de uma metodologia analítico-reconstrutiva, com o procedimento da revisão bibliográfica temática, examinando dois aspectos: avanços e insuficiências. Conclui-se que houve avanços consideráveis em relação a definição do conceito de gestão democrática, mas que há a necessidade da existência de normas legais que regulamentem o princípio – normas ainda em construção, mesmo depois de três décadas -, bem como a implementação de práticas sociais que reflitam a gestão democrática, indicando a importância do debate acadêmico e da pesquisa científica para dar sustentação ao tema.
Plant Desiccation Tolerance: A Survival Strategy with Exceptional Prospects for Climate‐Smart Agriculture
Authors: Hilhorst Henk W.M. , Farrant Jill M. 
Published: October 2018

Abstract
Drought is one of the main threats to agriculture worldwide because most of our staple crops are not very tolerant to dehydration stress. Some 135 species of angiosperms, however, are extremely tolerant of severe drought. These so‐called resurrection plants are desiccation tolerant because they can withstand drying to water contents below 0.1 gram water per gram dry weight and remain viable for extended periods of time, similar to most seeds. Indeed, recent research has shown that mechanisms of desiccation tolerance of different species, be it vegetative tissues or seeds, utilise the same basic ingredients, including anti‐oxidants, chaperone proteins, and specific carbohydrates. However, there is species‐specific behaviour, related to habitat, e.g. in cell wall properties and the manner in which photo‐oxidative damage is prevented upon drying. Crop plants produce desiccation‐tolerant seeds and, hence, possess the genomic information required for desiccation tolerance, but this is exclusively expressed in the seeds. Elucidation of the mechanisms of desiccation tolerance may enable the ‘release’ of this characteristic in the leaves, stems, and roots.
Thirty years of research on online learning
Authors: Mayer Richard E. 
Published: October 2018

SummaryThis paper presents a personal account of developments in research on online learning over the past 30 years. Research on how to design online instruction represents an example of applying the science of learning to education. It contributes to the science of learning (as exemplified by developments in cognitive load theory, the cognitive theory of multimedia learning, and incorporating metacognitive, motivational, and affective aspects of learning), the science of instruction (as exemplified by the continuing development of research‐based principles of instructional design), and the science of assessment (as exemplified by supplementing self‐report surveys and retention tests with multilevel transfer tests, log file data during learning, and cognitive neuroscience measures of cognitive processing during learning). Some recurring themes are that learning is caused by instructional methods rather than instructional media, so research should focus on features that are uniquely afforded by digital learning environments; instructional practice should be grounded in rigorous and systematic research, including value‐added experiments aimed at pinpointing the active ingredients in online instruction; research in online learning should identify boundary conditions under which instructional techniques are most effective; and research in online learning should test and contribute to learning theory.
Effect of Glucose on Liposome–Plasma Protein Interactions: Relevance for the Physiological Response of Clinically Approved Liposomal Formulations
Authors: Palchetti Sara , Digiacomo Luca , Pozzi Daniela , Zenezini Chiozzi Riccardo , Capriotti Anna Laura , Laganà Aldo , Coppola Roberto , Caputo Damiano , Sharifzadeh Mohammad , Mahmoudi Morteza , Caracciolo Giulio 
Published: October 2018

AbstractRecently, the concept is emerging that the reduced success of nanoparticles in clinical practice is due to the adsorption of the “biomolecular corona (BC),” which alters their biological identity. Apart from protein variations, alterations in the human metabolome may change the BC decoration, which has poorly been addressed so far. Here, glucose is used as a model metabolite and how the interactions between liposomes (as a model nanoparticle) and plasma proteins are influenced by normal and diabetic sugar blood levels is explored. As model liposomes, Doxoves and Onivyde are used that are used for the treatment of breast and metastatic pancreatic cancer, respectively. It is shown that glucose does affect the structure and composition of BC. The biological effects of liposome–BC complexes are investigated in MCF 7 and MDA‐MB‐231 breast cancer cells for Doxoves and in pancreatic adenocarcinoma (PANC‐1) and insulinoma (INS‐1) cells for Onivyde. In the presence of glucose, the cellular toxicity of liposome–protein complexes and uptake by human monocytic THP1 cell line increases. These results demonstrate that alterations in glucose concentration, and more generally changes in the human metabolome, may play a fundamental role in the biological identity of liposomes and, consequently, on their in vivo physiological readouts including therapeutic efficacy.
Polymer Self‐Assembled BMSCs with Cancer Tropism and Programmed Homing
Authors: Zhang Shuyi , Liu Yuqing , Derakhshanfar Soroosh , He Wanming , Huang Qiong , Dong Shumin , Rao Jinjun , Luo Gao‐Xing , Zhong Wen , Liao Wangjun , Shi Min , Xing Malcolm 
Published: October 2018

AbstractTargeted therapy can improve the accuracy of diagnosis and treatment in the field of cancer management. Cellular surface engineering can enhance cell functions via mounting functional molecules onto cellular membranes. A novel amphiphilic hyperbranched polymer (AHP) conjugated with oleic acid (OA) and tumor‐targeted ligand folic acid (FA) is employed. The lipophilic chain can self‐assemble and infuse with the cytomembrane of bone marrow mesenchymal stem cells (BMSCs) with the end of FA left on the outside for targeting. The polymer tailored BMSCs can enhance tumor tropism in gastric cancer. BMSCs are characterized by the low immunogenicity and tumor tropism, which makes them promising targeting carriers. Regarding the integrated advantages of these two vectors, it is demonstrated that the functional amphiphilic AHP‐OA‐FA enhances the tumor tropism of BMSCs. Flow cytometry, standard MTT assay, and wound‐healing assay show that AHP‐OA‐FA has no influence on CD expression, proliferative capacity, and cell motility of BMSCs, respectively. Furthermore, in vitro transwell assay and ex vivo fluorescence image verify that AHP‐OA‐FA enhances tumor tropism of BMSCs compared to BMSCs and AHP‐OA‐Rhodamine B‐BMSCs. Finally, histological analysis demonstrates that AHP‐OA‐FA causes no damage to major organs. The results of this study suggest that living BMSCs self‐assembled with a polymer might be a promising vehicle for targeted delivery to cancer cells.
Microfluidics‐Based Biomaterials and Biodevices
Authors: Dong Ruihua , Liu Yong , Mou Lei , Deng Jinqi , Jiang Xingyu 
Published: October 2018

AbstractThe rapid development of microfluidics technology has promoted new innovations in materials science, particularly by interacting with biological systems, based on precise manipulation of fluids and cells within microscale confinements. This article reviews the latest advances in microfluidics‐based biomaterials and biodevices, highlighting some burgeoning areas such as functional biomaterials, cell manipulations, and flexible biodevices. These areas are interconnected not only in their basic principles, in that they all employ microfluidics to control the makeup and morphology of materials, but also unify at the ultimate goals in human healthcare. The challenges and future development trends in biological application are also presented.
Design of Nanostructured Surfaces Based on Metal NP Precipitation Strategy and their Catalytic Application
Authors: Guarrotxena Nekane , Garrido Leoncio , Quijada‐Garrido Isabel 
Published: October 2018

AbstractThe fabrication of functional surfaces based on arrangements of metallic nanoparticles (MNPs) is challenging for biomedical, optoelectronic, and catalytic applications. Herein, the fabrication of 3D nanostructured microfibers is reported by the controlled cooperative precipitation of MNPs on electrospun polymer fiber mats, at the critical solution temperature of a thermoresponsive copolymer coating the MNPs surface. To obtain the metallic decorated surfaces, several factors must be taken into consideration, such as the previous functionalization of the metallic nanoparticle surface and the selection of a suitable polymer concentration, pH, and temperature. The results show that the plasmonic properties of the prepared surfaces depend on the solution temperature. Among potential applications, the high specific area of the resulting Au@polymer@fiber nanocomposites is ideal to be exploited for catalytic applications. Thus, the reduction of 4‐nitrophenol has been studied as a model.