bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interventions in Foster Family Care: A Systematic Review
Authors: Bergström Martin , Cederblad Marianne , Håkansson Kickan , Jonsson Ann Kristine , Munthe Christian , Vinnerljung Bo , Wirtberg Ingegerd , Östlund Pernilla , Sundell Knut 
Published: March 2019

Objective: Foster family care is associated with adverse short- and long-term consequences for the child. A systematic review was conducted on interventions for foster children and foster careers. Method: A comprehensive search process was used to find eligible interventions evaluated in randomized controlled trials or quasi-experimental studies. The quality of studies was assessed with GRADE, and effects were synthesized using meta-analytic methods. Results: In all, 28 publications of 18 interventions, including 5,357 children, were identified. Only three specific interventions had sufficient confidence of evidence. No study had examined tools for foster parent selection nor had evaluated preservice programs related to outcomes. Discussion: These analyses provide new insights and hope into the field of systematic interventions in foster care. The overall results indicate that it is possible to improve eight outcomes but cannot point out which programs are superior. Ethically, social care organizations should systematically collect knowledge about effects and side effects.
Biomechanical Evaluation of Spring Ligament Augmentation With the FiberTape Device in a Cadaveric Flatfoot Model
Authors: Aynardi Michael C. , Saloky Kaitlin , Roush Evan P. , Juliano Paul , Lewis Gregory S. 
Published: March 2019

Background: The structural importance of the spring ligament complex in arch stability has been described. Furthermore, the pathology of this complex is often noted in patients with posterior tibial tendon dysfunction. The purpose of this biomechanical study was to evaluate spring ligament repair alone versus augmentation with the FiberTape device in a cadaveric flatfoot model. Methods: Eight paired, below-the-knee, cadaveric specimens underwent flatfoot creation and reconstruction. The experimental group received augmentation with FiberTape (InternalBrace). After potting, specimens were loaded statically to measure talonavicular contact pressures and flatfoot correction. Cyclic loading was performed in a stepwise fashion. Loading was performed at 1 Hz and 100 cycles, at 100-N intervals from 500 to 1800 N, with the Achilles tendon also loaded to simulate weightbearing in the postoperative period. Results: Control specimen analysis demonstrated failures of 8 of 8 (100%) spring ligament suture repairs, occurring through suture cut-through (5 specimens), suture fatigue and elongation (2), or knot failure (1). One of 8 (12.5%) FiberTape-augmented repairs failed after cyclic loading. The difference in number of repair failures was statistically significant between the 2 groups ( P = .0014). Analysis revealed that at forces of 1600 N ( P = .03) and 1700 N ( P = .02) there were statistically significant differences between the FiberTape-augmented group and the control group, with a greater collapse in the lateral Meary talo–first metatarsal angle in the controls. There was no significant difference or abnormal increase in contact pressures of the talonavicular joint in both groups. Conclusion: FiberTape augmentation of the spring ligament appears biomechanically safe and effective under cyclic loading. Clinical relevance: Spring ligament augmentation with this device may be another biomechanically safe and reasonable treatment modality for surgeons during flatfoot reconstruction. It is possible that early protected weightbearing after these procedures may be performed.
Motivation, expectations and understanding of patients and their parents seeking orthodontic treatment in specialist practice
Authors: Geoghegan Finn , Birjandi Ana Ahmadi , Machado Xavier Guilherme , DiBiase Andrew T 
Published: March 2019

Objectives: To determine patient and parent/guardian motivation, expectation and understanding of orthodontic treatment. Design: A self-completion questionnaire survey of new patients referred for orthodontic assessment. Setting: Specialist practices in Surrey and Berkshire (United Kingdom). Participants: A total of 500 questionnaires were issued (250 were issued to patients and 250 to parents). Methods: The survey was based on a self-completed questionnaire which was issued at the assessment appointment. Both questionnaires were adapted and extended from originally validated questionnaires previously used in a hospital setting. Patients and parents were asked to complete separate anonymous questionnaires. The patient questionnaire consisted of 24 closed-ended questions divided into three domains: motivation; understanding; and expectation of orthodontic treatment. The parent questionnaire consisted of 13 questions covering the same three domains Results: The response rate for the patient and parent questionnaires was 95% and 91%, respectively. Forty-seven percent of the patients were aged 11–13 years. In 77% of cases, the referral was initiated by their dentist. Only 3% of patients thought there was nothing wrong with their teeth. There was a poor understanding of what a retainer is and for how long patients are expected to use it. Conclusions: Referral for orthodontic treatment was initiated by the patients’ general dental practitioner in the majority of the cases. The anticipation of improved dental appearance was a prime motivating factor. Participants had realistic expectations and there was a good acceptance of appliances and dental extractions for orthodontic treatment. Nevertheless, both patients and parents/guardians were less well informed on the nature and duration of orthodontic retention.
Leptin levels in gingival crevicular fluid during canine retraction: in vivo comparative study
Authors: Sar Sanjit Kumar , Shetty Divya , Kumar Piush , Juneja Saurabh , Sharma Payal 
Published: March 2019

Objective: To evaluate and compare the leptin levels in gingival crevicular fluid (GCF) and rate of canine retraction using an elastomeric chain and nickel–titanium (NiTi) closed coil spring. Design: In vivo, clinical study. Setting: Orthodontic department at ITS Centre for Dental Studies and Research, Ghaziabad, India. Participants: Twenty-seven patients reported to the Department of Orthodontics at ITS Centre for Dental Studies and Research. Methods: Twenty-seven patients were included in the study in which canine retraction was carried out with an elastomeric chain and NiTi closed coil spring on either side of the arch applying 150 g of force on both sides. GCF samples were collected before the commencement of canine retraction, on the first, seventh and 21st day after application of force and were analysed for leptin levels by the ELISA technique. Impressions for the study model were taken at baseline and after 21 days to measure the rate of tooth movement bilaterally with an electronic digital calliper. Results: The results obtained within both groups showed a significant decrease in leptin levels from baseline to 21 days ( P = 0.0001). There was no significant difference in leptin levels between both groups, but leptin levels decreased more in the NiTi closed coil spring group. The rate of tooth movement is not significantly different between both groups, but space closure is faster in the NiTi closed coil spring group. Conclusions: Leptin levels in GCF showed a significant decrease during canine retraction using an elastomeric chain and NiTi coil spring; there was no significant difference in the rate of tooth movement between both the groups.
Comparison of all suture fixation with tension band wiring and plate fixation of the olecranon
Authors: Phadnis Joideep Sunil , Vaughan Alex , Luokkala Toni , Peters Jonathon , Watson Jay J , Watts Adam 
Published: March 2019

Background Tension band wiring and plate fixation are common techniques used to stabilize simple olecranon fractures and osteotomies of the olecranon. All suture fixation is an alternative technique but has not been compared previously to these traditional methods. The aim of this study was to compare the clinical and radiographic outcomes of the three techniques. Methods One hundred and sixty-eight consecutive Mayo type 1 and 2 olecranon fractures (n = 138) and olecranon osteotomies (n = 30) with a minimum follow-up time of one year were compared. The primary outcome measure was the rate of re-operation. Secondary outcome measures were the incidence of complications, rate of radiographic union and incidence of radiographic reduction loss. Results Fixation was performed using tension band wiring in 89 patients, plating in 38 patients and suture fixation in 41 patients. There was no significant difference in the fracture type according to the Mayo classification between the groups. The re-operation rate was significantly higher in the tension band wiring group (36%) compared with both the plate group (11%, p = 0.03) and the suture group (2%, p = 0.002). There were two revision fixations in the tension band wiring group and one in the suture group. There was one asymptomatic non-union in the suture group. All other fractures and osteotomies achieved radiographic union. Conclusion Suture fixation of simple olecranon fractures and osteotomies was reliable in providing stable union and had a significantly lower re-operation rate when compared with tension band wiring.
Pregnant pause: should we screen for sleep disordered breathing in pregnancy?
Authors: Perkins Alex , Einion Alys 
Published: March 2019

Physiological and hormonal changes in pregnancy can contribute towards sleep disordered breathing in pregnant women (SDBP). When present, SDBP increases the risk of several adverse maternal and fetal outcomes independent of factors such as age, weight and pre-existing maternal comorbidities. SDBP is underdiagnosed and may be hard to recognise because the presentation can be difficult to differentiate from normal pregnancy and the severity may change over the course of gestation. Timely intervention seems likely to help reduce adverse outcomes, but the relative benefits of intervention are still unclear. The definition of what constitutes a sleep-related breathing “disorder” in pregnancy may be different to the general population and so traditional thresholds for intervention may not be relevant in pregnancy. Any modifications to the disease definition in this group, or implementation of more intensive screening, may result in overdiagnosis. Further research is needed to help clinicians evaluate the balance of benefits and harms in this process. Until this is clearer there is a strong imperative for shared decision making in screening and treatment decisions, and screening programmes should be monitored to assess whether improved outcomes can be achieved at the healthcare system level.Key pointsUntreated sleep disordered breathing in pregnancy poses risks to maternal and fetal wellbeing, but it is underdiagnosed.Careful approaches to screening could improve rates of diagnosis, but thresholds for and benefits of intervention are unclear.Clinical guidelines and screening programmes for sleep disordered breathing in pregnancy need to consider the potential harms of overdiagnosis and should involve shared decision making and careful monitoring of outcomes relevant to the individual.Educational aimsExplore current knowledge of the prevalence of sleep disordered breathing in the pregnant population.Explore the relationship between sleep disordered breathing and adverse outcomes.Understand the approaches to diagnosis and management of sleep disordered breathing in pregnancy.Explore issues around screening, underdiagnosis and overdiagnosis in the context of sleep disordered breathing in pregnancy.
Accumulation of wear and tear in archival and library collections. Part I: exploring the concepts of reliability and epidemiology
Authors: Duran-Casablancas Cristina , Grau-Bové Josep , Strlič Matija 
Published: March 2019

Abstract
Wear and tear is the outcome of degradation most frequently reported in assessments of archival and library collections. It is also problematic to study in controlled experiments, due to the difficulty in reproducing the conditions in which original objects are kept and used in archives and libraries. Hence, data collected from actual collections, for instance during surveys, could provide the evidence on how wear and tear occurs. However, to be useful, such data need to be purposely collected and analysed: unlike the usual collection surveys, the aim is not to quantify the prevalence of a certain damage type but to provide evidence on how such damage occurs. In this paper we explore whether two approaches used in other disciplines could be useful: reliability engineering, the method that deals with failure in complex systems, and epidemiology, which explores diseases in defined populations. We show that based on reliability engineering we can decide which data related to the causes of mechanical failure should be collected during collection surveys, while using epidemiology we can develop the study design and the data analysis needed to study the relationship between mechanical failure, and the factors that might affect the degree of failure. The results of epidemiological studies in heritage collections could provide quantitative evidence of patterns of decay in collections, and corroborate the qualitative analysis provided by reliability. The results can directly support collection management decisions or can be used in mathematical models in which the effect of preservation measures is explored.
Expression of PD-L1 in primary breast carcinoma and lymph node metastases
Authors: Alves Alice M. , Paredes Joana , Schmitt Fernando 
Published: March 2019

Abstract
Background
Programmed cell death ligand 1 (PD-L1) is a predictive biomarker of the response of immunotherapy in some types of cancer. In the last years it was described its expression in breast cancer, namely in triple-negative breast cancer (TNBC) cases. In order to better understand the prognostic value of PD-L1 in breast cancer, this study analysed its expression in a series of primary tumours and respective nodal metastases.

Methods
PD-L1 expression was evaluated by immunohistochemistry in a series of 52 breast cancer cases and paired lymph node metastasis and correlate with the clinicopathological features of the primary tumour. The TNBC cases were re-classified using morphological and immunohistochemistry surrogate markers and the expression of PD-L1 was correlate with the different subtypes.

Results
It was observed that the majority of the cases with PDL-1 positive in the nodal metastasis did not express PD-L1 in the primary tumour (90.0%, 10 out of 11 cases). In addition, from the cases with a negative PD-L1 expression in the primary tumour, 23.8% expressed PD-L1 in the metastasis (10 out of 42 cases).No relationship was found between the PD-L1 expression in nodal metastasis and the clinicopathological features of the primary tumour. Finally, basal-like immunosuppressed (BLIS) TN tumours seem to be less prone to express PD-L1.

Conclusion
Although without statistical significance, there is a gain in terms of the PD-L1 expression in the nodal metastasis when compared to the primary tumour. This may have therapeutic implications on immunotherapy that blocks the PD-1/PD-L1 pathway.
The potential impact of age, gender, body mass index, socioeconomic status and dietary habits on the prevalence of dental caries among Egyptian adults: a cross-sectional study
Authors: Abbass Marwa M.S. , AbuBakr Nermeen , Radwan Israa Ahmed , Rady Dina , El Moshy Sara , Ramadan Mohamed , Ahmed Attera , Al Jawaldeh Ayoub 
Published: March 2019

Background:Dental caries is a major public health problem and the most widespread chronic disease to affect individuals throughout their lifetime. Little information exists about the prevalence of dental caries among Egyptian adults. Therefore, this study investigated the dental caries experience among Egyptian adults in correlation with different risk factors.Methods:A total of 359 Egyptian adults (age range, 18-74 years) were examined over a period of 3 months, starting on the 15thof November 2017 until the 13thof January 2018. Socio-demographic data, brushing frequency, body mass index (BMI) and eating habits were recorded and collected using a questionnaire. Dental examination was performed using the Decayed, Missing and Filled tooth (DMFT) index.Results:In total, 86.63% of participants had dental caries experience. Of the participants, 60.45%, 48.47% and 55.43% had at least one decayed, missing and filled tooth, respectively. The mean number of decayed, missing, filled or DMFT for the whole sample were 2.4±3.6, 1.98±3.99, 1.79±2.45, 6.09±5.7, respectively. Decayed teeth were inversely correlated with socio-economic status (SES), education level, brushing frequency and milk consumption and positively correlated with grains, junk food and soda drinks consumption. Missing teeth were inversely correlated with SES, education level and brushing frequency, while positively correlated with age, BMI and caffeinated drink consumption. Conversely, filled teeth were positively correlated with age, BMI, SES and education level, while negatively correlated with grains and sugars in drinks.Conclusion:The present study clarifies that age, BMI, SES, education level and brushing frequency are risk factors significantly associated with dental caries prevalence amongst Egyptian adults. Egyptian adults' dietary habits might lead to obesity, which indirectly causes dental caries rather than directly as in children.
Preliminary assessment of the utilization of durian peel liquid smoke as a natural preservative for mackerel
Authors: Faisal Muhammad , Gani Asri , Mulana Farid 
Published: March 2019

Background: Durian peel is a type of biomass waste that contains cellulose, hemicelluloses, and lignin. The pyrolysis of these compounds results in production of liquid smoke which can be used as a natural preservative to replace current synthetic preservatives. This research assessed the ability of liquid smoke produced during pyrolysis of durian peel to preserve fish. Methods: Dry durian peel waste underwent batch reactor pyrolysis at 340°C and 380°C, resulting in production of liquid smoke (grade 3), charcoal, and tar. This liquid smoke was then distilled at 190°C to produce grade 1 liquid smoke, which was used to preserve mackerel. The preservation process was conducted by soaking the mackerel samples in liquid smoke at 0.5, 1, 2, and 3% concentration levels followed by observations every 6 hours. Tests to determine the total volatile base (TVB) content, antibacterial quality of the liquid smoke and organoleptic quality of the fish were conducted in order to assess the preservation properties of the liquid smoke. Results: Tests on the antibacterial effects showed that the liquid smoke inhibited the growth of Escherichia coli and Staphylococcus aureus on fish even at low concentrations. At 54 hours, the TVB values remained below 30 mg nitrogen/g, indicating that the fish was still safe for human consumption. Results from the organoleptic tests showed that the concentration of liquid smoke influenced the preservation effects. Conclusions: At a concentration of 2–3%, the fish samples possessed acceptable flavor, taste, color and texture for up to 48 hours of soaking. However, the best conditions were obtained with a 3% concentration of liquid smoke (produced with 340°C pyrolysis), as the fish was still considered acceptable for up to 42 hours.
Latent Complete-Lattice Structure of Hilbert-Space Projectors
Authors: Herbut Fedor 
Published: March 2019

To uncover the hidden complete-lattice structure of Hilbert-space projectors, which is not seen by the operator operations and relations (algebraically), resort is taken to the ranges of projectors (to subspaces—to geometry). Taking the range of a projector is completed into a bijection of all projectors onto all subspaces of any finite or countably infinite dimensional Hilbert space. As a second step, this basic bijection is upgraded into an isomorphism of partially ordered sets utilizing the sub-projector relation on the one hand, and the subspace relation on the other. As a third and final step, the basic bijection is further upgraded to isomorphism of complete lattices. The complete-lattice structure is derived for subspaces, then, using the basic bijection, it is transferred to the set of all projectors. Some consequences in the quantum-mechanical formalism are examined with particular attention to the infinite sums appearing in spectral decompositions of discrete self-adjoint operators with infinite spectra.Quanta 2019; 8: 1–10.
Congenital Falciparum Malaria with Chloroquine Resistance Type ll
Authors: Dianto Dianto , Rampengan T. H. 
Published: March 2019

A case of congenial falciparum malaria has been reported. The diagnosis was based ·on history of illness, clinical manifestations, age of the child and presence of the ring form falciparum malaria in the peripheral blood films.
Treatment with chloroquine showed resistance type II, though treatment with quinine was successful.
In malaria endemic areas, although rare, one must be aware of the possibility of congenital malaria.
Patent Ductus Arteriosus Before and After Surgery
Authors: Madiyono Bambang , Oesman Ismet N. , Sastroasmoro Sudigdo , Putra Sukman Tulus , Soelaiman Eva Jeumpa , Rachmad Kukuh Basuki 
Published: March 2019

Twenty five patients with patent ductus arteriosus, who had undergone surgical closure were studied retrospectively. Girls were more affected than boys; the sex ratio was 4 : I. Associated cardiac lesions were diagnosed in 3 patients, two with ventricular septal defect and one with congenital mitral stenosis. Congestive heart failure was diagnosed in 5 patients before surgery. Typical continuous murmur was heard in most cases (76%), while in the rest only systolic murmur was detected. Electrocardiographic left atrial enlargement, left ventricular hypertrophy and right ventricular hypertrophy were found in 8%, 48% and 40%, respectively.Cardiomegaly with increased pulmonary vascular markings was found in 60% of cases, while ratio of left atrial to aortic root diameter greater than 1.2 was detected in 60% of patients. The PDA could be directly visualized by echocardiography in 15 cases.Cardiac catheterization was performed in 17 cases, 47% with hyperkinetic pulmonary hypertension, 41% with high pulmonary flow without pulmonary hypertension and 12% with mild increased pulmonary flow. The pulmonary-systemic flow ratio (Qp/Qs) was more correlated to pulmonary vascular markings rather than to cardio-thoracic ratio. Division of the ductus was the procedure of choice, but in 16% of cases ductal ligation was performed because of technical reasons. Postoperative catch-up in both weight and height was observed more clearly in children operated at earlier age. Ejection systolic murmur was still detected in 2 patients, in whom hyperkinetic pulmonary hypertension existed prior to surgery. No cardiomegaly was found in patients followedup I year or more after surgery. The mortality was nil.