bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clarification of apple juice using activated sepiolite as a new fining clay
Authors: Mirzaaghaei Marzieh , Goli Sayed Amir Hossein , Fathi Milad 
Published: February 2018

AbstractThe function of acid-activated sepiolite clay was evaluated for use in the clarification of apple juice. Optimizing the clarification process was done using response surface methodology (RSM) considering juice turbidity as a response. The efficiency of sepiolite in terms of clarification was compared to that of bentonite and a combination of these fining agents with gelatin and silica gel at optimal conditions. The conditions of 0.05% clay concentration at a temperature of 50°C for 7 h were deemed optimal in terms of juice clarification. The present results showed that treatment of sepiolitegelatin-silica gel was the most active fining agent with 99.7% reduction in apple-juice turbidity. The rate of turbidity, the viscosity, the total phenolic contents and the colour changes were fitted to first-, zero-, first- and zero-order kinetic models, respectively.
Mechanisms of platelet clearance and translation to improve platelet storage
Authors: Quach M. Edward , Chen Wenchun , Li Renhao 
Published: February 2018

AbstractHundreds of billions of platelets are cleared daily from circulation via efficient and highly regulated mechanisms. These mechanisms may be stimulated by exogenous reagents or environmental changes to accelerate platelet clearance, leading to thrombocytopenia. The interplay between antiapoptotic Bcl-xL and proapoptotic molecules Bax and Bak sets an internal clock for the platelet lifespan, and BH3-only proteins, mitochondrial permeabilization, and phosphatidylserine (PS) exposure may also contribute to apoptosis-induced platelet clearance. Binding of plasma von Willebrand factor or antibodies to the ligand-binding domain of glycoprotein Ibα (GPIbα) on platelets can activate GPIb-IX in a shear-dependent manner by inducing unfolding of the mechanosensory domain therein, and trigger downstream signaling in the platelet including desialylation and PS exposure. Deglycosylated platelets are recognized by the Ashwell-Morell receptor and potentially other scavenger receptors, and are rapidly cleared by hepatocytes and/or macrophages. Inhibitors of platelet clearance pathways, including inhibitors of GPIbα shedding, neuraminidases, and platelet signaling, are efficacious at preserving the viability of platelets during storage and improving their recovery and survival in vivo. Overall, common mechanisms of platelet clearance have begun to emerge, suggesting potential strategies to extend the shelf-life of platelets stored at room temperature or to enable refrigerated storage.
Differentiated osteoblasts derived decellularized extracellular matrix to promote osteogenic differentiation
Authors: Jeon Jin , Lee Min Suk , Yang Hee Seok 
Published: February 2018

Abstract

Background
The extracellular matrix (ECM) can directly or indirectly influence on regulation of cell functions such as cell adhesion, migration, proliferation and differentiation. The cell derived ECM (CD-ECM) is a useful in vitro model for studying the comprehensive functions of CD-ECM because it maintains a native-like structure and composition. In this study, the CD-ECM is obtained and a test is carried out to determine the effectiveness of several combinations of decellularized methods. These methods were used to regulate the optimal ECM compositions to be induced by osteogenic differentiation using primary isolated osteoblasts.

Result
We investigated the effect of osteoblasts re-seeded onto normal osteoblast ECM under the growth medium (GM-ECM) and the osteogenic differentiation medium (OD-ECM). The osteoblasts were then cultured statically for 1, 2, and 4 weeks in a growth medium or differentiation medium. Before osteoblast culture, we performed immunostaining with filamentous actin and nuclei, and then performed DNA quantification. After each culture period, the osteogenic differentiation of the osteoblasts re-seeded on the OD-ECMs was enhanced osteogenic differentiation which confirmed by alkaline phosphatase staining and quantification, Alizarin Red S staining and quantification, and von Kossa staining. The OD-ECM-4 W group showed more effective osteogenic differentiation than GM-ECM and OD-ECM-2 W.

Conclusions
The OD-ECM-4 W has a better capacity in a microenvironment that supports osteogenic differentiation on the GM-ECM and OD-ECM-2 W. The ECM substrate has a wide range of applications as cell culture system or direct differentiation of stem cell and excellent potential as cell-based tissue repair in orthopedic tissue engineering.
An Approach to Identify Delivery of Palliative Radiation Therapy Using Health Care Claims Data: A Proof-of-Concept Application of a Visual Analytics Tool
Authors: Onukwugha Eberechukwu , Jayasekera Jinani , Gardner James , Malik Sana , Mullins C. Daniel , Hussain Arif , Ciezki Jay P. , Reddy Chandana A. , Seal Brian , Valderrama Adriana , Kwok Young 
Published: February 2018

Purpose There is limited information on the use of data visualization tools for health services research applications. We provide a proof-of-concept application that focuses on claims-based measures of palliative radiation therapy. We investigate whether a guided, data-driven investigation contributes information for subsequent statistical analysis and algorithm development. Methods This retrospective cohort study used linked registry and claims data on men who were diagnosed with stage IV M0 or stage IV M1b prostate cancer between 2005 and 2009, with associated claims from 2005 through 2010, and receiving radiation therapy. Preprocessing of data was accomplished by using EventFlow software to investigate longitudinal patterns in claims for radiation therapy in the 13 months after cancer diagnosis. Guided by results from EventFlow, we developed descriptive statistics to investigate the length of radiation therapy, use of bone metastasis coding, and mortality between M1b and M0 patients. Results A total of 1,151 patients met the inclusion criteria. Taking advantage of the novel aggregation capability of EventFlow, we observed differences in the length of radiation therapy and the use of bone metastasis coding between men with (M1b) and without (M0) a diagnosis of bone metastasis. Seventy-nine percent of M1b patients received radiation for a duration ≤ 4 weeks, which suggested palliative radiation (to the bone). Seventy-six percent of M0 patients received radiation for ≥ 6 weeks, which suggested radiation to the prostate. Mortality was higher among those who received a shorter duration of radiation therapy compared with those who received a longer duration of therapy. Conclusion Use of EventFlow, followed by statistical analysis of the linked registry and claims data, identified useful components of a claims-based measure of radiation to the bone.
Comparing four radiotherapy techniques for treating the chest wall plus levels III–IV draining nodes after breast reconstruction
Authors: Lancellotta Valentina , Iacco Martina , Perrucci Elisabetta , Falcinelli Lorenzo , Zucchetti Claudio , de Bari Berardino , Saldi Simonetta , Aristei Cynthia 
Published: February 2018

Objective:
To compare the dosimetric outcomes of four radiotherapy (RT) techniques for treating the chest wall plus draining nodes after mastectomy and breast reconstruction.

Methods:
Three-dimensional conformal radiotherapy, linac-based intensity modulated RT, helical tomotherapy (HT) and direct tomotherapy treatments were planned for 40 breast cancer patients. Dose prescription was 50 Gy. Plans were compared in terms of doses to the planning target volume, organs at risk and the homogeneity index. The non-parametric Friedman test for paired data and the Conover post hoc analysis were used for data analysis.

Results:
HT provided the highest D90 and D98% and the lowest HI, V107% and D2%. HT was associated with the lowest D2% and V25 Gy to the heart in left-sided treatments but the mean cardiac dose was highest. HT provided the highest V5 Gy and V20 Gy to the ipsilateral lung, but the V30 Gy was lower. The contralateral breast and lung were more exposed with HT.

Conclusion:
The present dosimetric study together with daily use of CT-MV image guided RT have led us to opt for HT after mastectomy and breast reconstruction and to draw up a suitable protocol for treating the chest wall and levels III and IV draining nodes.

Advances in knowledge:
HT is a suitable for treating the chest wall and levels III and IV draining nodes.
A study protocol for a randomized controlled trial on the prevention of atrial fibrillation after coronary artery bypass grafting surgery using Tocotrienol, an isomer of Vitamin E derived from palm oil
Authors: Musa Ahmad Farouk , Dillon Jeswant , Md Taib Mohamed Ezani , Mohamed Yunus Alwi , Nordin Rusli Bin , Kah Hay Yuen 
Published: February 2018

Background: One of the most common complications following coronary artery bypass grafting (CABG) surgery is atrial fibrillation (AF), which contributes towards increasing morbidity and mortality, length of hospital stay (LoHS) and reduced quality of life (QoL) of patients. Objectives: To determine whether the intake of Tocotrienol, a Vitamin E isomer derived from palm oil, before and immediately following CABG prevents AF, reduces LoHS, and improves the QoL of patients. Protocol: The study is registered with the National Medical Research Register with a trial number NMRR-17-1994-34963 and designed as a prospective, randomized controlled trial (RCT) with parallel groups. The experimental group will receive two 200mg Tocotrienol capsules each day, while the control group will receive two identical placebo (palm Super Olein) capsules per day. ECG readings will be used to detect AF post operatively, LoHS will be measured by checking the records from the National Heart Institute Hospital register, and the health-related Quality of Life (HRQoL) analysis (the Malay version of the Short Form 36 Questionnaire) will be used to analyse QoL. The sample size was calculated to be 140 in each arm of the RCT for a power of 0.8 and a significance level of 0.05. Funding: HOVID Berhad funds this research project. Expected outcomes: The primary endpoint is the development of postoperative AF, whilst the secondary endpoints are the LoHS and HRQoL of patients post CABG. Future implications: Prevention of AF and its complications such as cardiovascular or cerebrovascular events, especially stroke, is an important output. Malaysia is one of the biggest producers and exporters of palm oil and palm oil products. Thus, the possibility of marketing Tocotrienol, in reducing AF post CABG surgery, is a very important proposition indeed. Trial number: NMRR-17-1994-34963
Xylariales: First results of mycological exploration in the Sangay and Llanganates National Park, Ecuador
Authors: Guevara María-Fernanda , Salazar Paula , Mátyás Bence , Ordoñez María-Eugenia 
Published: February 2018

In the present study fungi collections were sampled in the Sangay (SP) and Llanganates (LP) National Parks, from which sequences of the regions of the internal transcribable spacer (ITS1-5.8S-ITS2) of the ribosomal DNA were obtained (RDNA). The taxonomic identification of fungi of the order Xylariales was achieved with the bioinformatic tools, to further study the phylogenetic relationships among the collected individuals and thus contribute with base information on their biological diversity, necessary to design and implement measures for the conservation of fungi. All records belong to the genus Xylaria, of these eight belong to PL and two to SP. A record was not identified at the species level, suggesting that it could be a new species. A phylogenetic tree of Maximum Likelihood was built.
Field Evaluation of an Electrostatic Air Filtration System for Reducing Incoming Particulate Matter of a Hen House
Authors: Zhao Yang , Chai Lilong , Richardson Brad , Xin Hongwei 
Published: February 2018

Abstract. As a result of the unprecedented highly pathogenic avian influenza (HPAI) outbreak in the U.S. in 2014-2015, some egg producers in the U.S. started using inlet air filtration to reduce the risk of disease transmission by air into hen houses. The removal efficiency of particulate matter (PM), the carrier of airborne pathogens, by such filtration systems has not been investigated. Therefore, this field study was conducted to evaluate the PM removal efficacy of an electrostatic air filtration system (consisting of a low-grade air filter and an electrostatic particle ionization, or EPI, system) installed at the inlet of a commercial high-rise hen house. The evaluation was performed in two test rounds over a one-year period. Results showed that average PM removal efficiencies in round 1 (spring to summer) and round 2 (late fall to spring) were respectively 66% and 29% for PM1, 66% and 30% for PM2.5, 66% and 31% for PM4, 68% and 36% for PM10, and 68% and 45% for total PM. Removal efficiency became unstable when the EPI system was inactive (i.e., when solely relying on the filter for PM removal). House static pressure and ventilation rate indicated considerable clogging of the filter media by dust accumulation and the need for replacement after ~16 weeks of use in the spring-to-summer sampling period (round 1); however, clogging was not an issue during the entire late fall-to-spring sampling period (24 weeks, round 2). The appearance of the filter changed gradually as dust accumulated with time, which can be captured by image analysis and used to judge filter dirtiness and lifespan. The findings of this field study provide insight into the efficacy of PM removal by such a low-cost air filtration system, which will help egg producers in their decision-making for disease prevention strategies. Keywords: Electrostatic particle ionization, Filtration, Hen house, Particulate matter, Reduction.
Improving In-Stream Nutrient Routines in Water Quality Models Using Stable Isotope Tracers: A Review and Synthesis
Authors: Jensen Alexandria , Ford William , Fox James , Husic Admin 
Published: February 2018

Abstract. Water quality models serve as an economically feasible alternative to quantify fluxes of nutrient pollution and to simulate effective mitigation strategies; however, their applicability is often questioned due to broad uncertainties in model structure and parameterization, leading to uncertain outputs. We argue that reduction of uncertainty is partially achieved by integrating stable isotope data streams within the water quality model architecture. This article outlines the use of stable isotopes as a response variable within water quality models to improve the model boundary conditions associated with nutrient source provenance, constrain model parameterization, and elucidate shortcomings in the model structure. To assist researchers in future modeling efforts, we provide an overview of stable isotope theory; review isotopic signatures and applications for relevant carbon, nitrogen, and phosphorus pools; identify biotic and abiotic processes that impact isotope transfer between pools; review existing models that have incorporated stable isotope signatures; and highlight recommendations based on synthesis of existing knowledge. Broadly, we find existing applications that use isotopes have high efficacy for reducing water quality model uncertainty. We make recommendations toward the future use of sediment stable isotope signatures, given their integrative capacity and practical analytical process. We also detail a method to incorporate stable isotopes into multi-objective modeling frameworks. Finally, we encourage watershed modelers to work closely with isotope geochemists to ensure proper integration of stable isotopes into in-stream nutrient fate and transport routines in water quality models. Keywords: Isotopes, Nutrients, Uncertainty analysis, Water quality modeling, Watershed.
Book Reviews
Authors: Browning Kathy , Kárpáti Andrea , Serjouie-Scholz Ava 
Published: February 2018

Abstract
Digital Technologies in Early Childhood Arts: Enabling Playful Experiences, MONA Sakr (2017) London and New York: Bloomsbury Academic, 198 pp., ISBN: 9781474271882, h/bk, £95.00
Art and Technology: The Practice and Influence of Art and Technology in Education, Luisa Menano and Patricia Fidalgo (eds) (2017) Rotterdam, the Netherlands: Sense Publishers, 160 pp., ISBN: 9789463008617, p/bk, US$43
Teaching Painting: How can Painting be Taught in Art Schools?, Ian Hartshorne, Donal Moloney and Magnus Quaife (eds) (2016) London: Black Dog Publishing, 424 pp., ISBN: 9781911164104, p/bk, £16.95
Towards an immanent read: Being with wool as text
Authors: Barney Daniel T. , Jo Draper Roni , Blakely Rachel E. , Bryant Leea L. , Bryso Natalie R. , Bueno Brianne E. , Chopelas Alexander H. , Conte Philip L. , Crofts Eliza F. , Cummings Hannah C. , DeLeeuw Rachel M. , Eldredge Kandree M. , Facer Moira A. , Forsyth Camille H. , Hancock Kallie A. , Harris Morgan P. , Hatch Jacob C. , Kingi Caitlin G. , Landeen Hannah , McCann Caroline P. , McGrath Chloe J. , Mendez Nichole M. , Money Madison M. , Murdoch Cayla R. , Murdoch Claire A. , Packer Hailey S. , Petersen Julia L. , Romanovitch Ryan M. , Sanders Micah M. , Sheffield Sydney A. , Sircable Mikaela R. , Stallings Steven G. , Steele Savannah , Stewart Sarah B. , Taylor Madeline A. , Vasquez Rocio , Webster Whitney K. 
Published: February 2018

Abstract
Two faculty and 35 students in a beginning art theory course at Brigham Young University engage with speculative realism(s), new materialism and object oriented ontology literature as they wash, spin and knit sheep wool in relation to Coffen’s notion of an immanent read.
Círculo de Investigación Artística: New materialist pedagogies of resistance
Authors: Bobadilla Mariana Pérez 
Published: February 2018

Abstract
In response to artistic training that is overly technical, the Circle of Artistic Research (C.A.R.) was organized to rearticulate the relationship of theory to art production. Their work helps understand how art education can extend the arguments of new materialism by creating alternative research formats that restore the relevance to the material. This article argues that the strategies in practice as research that the C.A.R. adopts emphasize materiality without neglecting content in a matter-meaning entanglement, with a collective and rhizomatic organization, and producing situated knowledge. The interpretative method is framed by the new materialisms of the school of Rosi Braidotti promoting critique and creativity as a form of resistance.
Paper presentation: Reconfiguring objects, reconfiguring meanings
Authors: Tillett Wade 
Published: February 2018

Abstract
This project takes up the intersection of medium and content as a place where they can radically reconfigure one another. The entire process is a sort of unlearning; the habitual use of paper is disrupted. Physicality and meaning merge and emerge. Readers’ doings interact and transform both the meaning and background – the content (meaning) that traditionally would be simply re-presented via sheets of paper (background). Troubling just a small, habitual action leads to remarkably different modes of knowing and being. Action, object, meaning, reader and author (re)form tentative self-altering assemblages. These assemblages spiral out in new directions, moving beyond the confines of authorial intent. (Re)new(ed) configurations of self, meaning and object spring forth, opening themselves to different vectors. In order to explore these possibilities, I ask that you print out this article double-sided and cut/fold/etc. as instructed.
TRANSFORMASI SOSIAL PADA UPACARA RAMBU SOLO DIRAPAI DI RANTEPAO TORAJA UTARA
Authors: Rahleda Rahleda 
Published: February 2018

This study examines the shift rambu solo dirapai ceremony in conjunction with the social changes that occurred in the Toraja people. This study covers the forms of commodification is happening in the ceremony, interpendensi and social relations, as well as forms of figuration and habitus as a supporting component of a shift in the ceremony rambu solo dirapai. In this paper illustrates that ritual rambu solo dirapai shifting meanings and social values in society, first carried out in order to customary funeral procession of bodies of the nobility, now used as a means to obtain the existence in society and have also been used as a commodity for the benefit of tourism, so the ceremony rambu solo dirapai who had now become profane sacred nature. At the local elite also changes the structure, which was once the relationship is between traditional leaders and communities are now going a new power relationship that is influenced by the government as the new power relations by making ceremony rambu solo dirapai as tourism attraction in Toraja. In the shift between traditional leaders and the government as the new power relations created a balanced power relationship so there is no contradiction in the ceremony rambu solo dirapai as indigenous and as a tourism commodity. Keywords: Ceremony Rambu Solo Dirapai, Social Transformation, Figuration
SOSIALISASI NILAI-NILAI AGAMA DI KALANGAN MAHASISWA PROGRAM STUDI SOSIOLOGI AGAMA UIN SUNAN KALIJAGA
Authors: Amin Muhammad 
Published: February 2018

Tulisan ini bertujuan untuk membahas problematika sosialisasi nilai-nilai agama di kalangan mahasiswa, terutama di kalangan mahasiswa Prodi Sosiologi Agama Fakultas Ushuluddin UIN Sunan Kalijaga. Tulisan yang merupakan hasil penelitian ini diharapkan dapat memberikan masukan dalam merancang format sosialisasi nilai-nilai agama yang tepat di kalangan generasi muda untuk mewujudkan nilai-nilai yang lebih baik di kalangan generasi muda Indonesia, mengingat bahwa dalam kehidupan sehari-hari tidak jarang ditemukan kesenjangan yang cukup tajam antara nilai-nilai agama dengan perilaku umat sehari-hari.Sosialisasi nilai-nilai agama di kalangan mahasiswa masih perlu peningkatan. Untuk sosialisasi nilai-nilai agama itu dibutuhkan keteladanan yang baik. Di samping itu, sosialisasi nilai-nilai di kalangan mahasiswa selayaknya melalui kegiatan yang menarik dan interaktif, Untuk menghindari pendidikan nilai yang bersifat indoktrinatif, para mahasiswa perlu didorong untuk dapat menemukan alasan-alasan yang mendasari keputusan moral yang diambilnya. Kata kunci: sosialisasi, nilai-nilai, mahasiswa