bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supporting principal supervisors: what really matters?
Authors: Honig Meredith I. , Rainey Lydia R. 
Published: July 2019

PurposeDistricts across the country are calling on their principal supervisors to shift from mainly focusing on operations and compliance to dedicating their time to help principals grow as instructional leaders. Learning theory elaborates that such support for principals demands that supervisors take a teaching-and-learning approach – which the authors define as consistently using particular strategies that are characteristic of high quality teachers and mentors across various apprenticeship settings – to their work with principals on their instructional leadership. Prior research on leadership supports these shifts but does not examine the conditions under which principal supervisors are able to persist and grow in taking a teaching-and-learning approach specifically. What are those conditions? The paper aims to discuss these issues.Design/methodology/approachThis paper addresses that question through a re-examination of data from two studies with socio-cultural learning theory as the conceptual framework. The authors primarily use observation data (approximately 760 hours), supplemented by 344 interviews and reviews of hundreds of documents.FindingsContrary to extant research the authors did not associate high quality outside coaching with the positive cases of principal supervision. Nor did hiring principal supervisors with requisite prior knowledge explain why some principal supervisors regressed and grew. Findings underscore the importance of supervisors of principal supervisors (SPSs) being principal supervisors’ main mentors and principal supervisors not over-relying on others for assistance but actively leading their own learning, especially through work with colleagues and protecting their time themselves.Originality/valueThis analysis distinguishes conditions that support principal supervisors in taking a teaching-and-learning approach to their work with principals. The authors elaborate key roles for chief academic officers and others who supervise principal supervisors typically overlooked in policy and research on district leadership. Findings reinforce the importance of mentoring to learning and also district leaders serving as main mentors for each other, rather than relying on outside coaching.
Impact of correspondent bank de-risking on money service businesses in Jamaica
Authors: Gordon Leo-Rey 
Published: July 2019

Purpose
The paper aims to provide needed quantitative assessments of the impact of the withdrawal of correspondent banking to small emerging economies. It serves to identify the extent to which global anti-money laundering and combatting the financing of terrorism (AML/CFT) standards have influenced global banks’ decision to withdraw correspondent banking from some jurisdictions and the subsequent economic spillover effects on other non-bank financial entities.

Design/methodology/approach
Separate semi-structured surveys are issued to banks and money services businesses in Jamaica. Analysis of the responses identify the initial impact of de-risking on banks and the subsequent spillover effect on the other aspects of the financial system.

Findings
Results show significant spillover effects on money services businesses in their ability to transact in foreign currency with local commercial banks. Further, the scale of this impact is greater and costlier for smaller entities.

Research limitations/implications
The economic consequences of the direct and indirect impact of correspondent bank de-risking are increased concentration risks and the potential expansion of shadow financial activity.

Practical implications
Tighter AML/CFT standards coupled with action of over-compliance has created unintended consequences for small developing countries across the globe. In Jamaica, commercial banks have either lost correspondent relationships or have had restrictions placed on the types of services available. It creates risks to economic growth and development through the hindrance of access to international financial markets for payments, trade and commerce.

Originality/value
This study is the first among research on the issue of correspondent bank de-risking to provide quantitative assessments of the impact on local financial systems.
From functional quality apparatus to meaningful enactment: UNISA as example
Authors: Zawada Britta 
Published: July 2019

Purpose
The purpose of this paper is to explore the concept of a culture of high quality and show how a culture of high or exceptional quality goes beyond the functional apparatus of quality assurance, the so-called props on the stage, to the enactment and ultimately to the shared meaning-making and webs of significance for both the institution and its staff, as well as for the students and the communities they come from and will ultimately serve.

Design/methodology/approach
In addition to a general literature review, the paper is a conceptual exploration using a desktop study with examples from UNISA’s (University of South Africa) practice, to develop a conceptual understanding of the concept of a quality culture in higher education. The types and nature of the evidence required for the different quality loci and units of analysis are explored. Areas for improvement are indicated and linked to strategic imperatives in the South African context such as pedagogical renewal and curriculum transformation.

Findings
Conceptually, a quality culture can be found in four different loci, namely, in the input or functional apparatus, through the enactment to, the individual outcomes and the communal outcomes of institutional activities. The paper also shows that there are different levels of a quality culture that may be found in each of these loci, namely, compliance for accreditation, academic peer review and communities of practice and ultimately transformative meaning-making that leads to innovation and excellence. The conceptual discussion also indicates that in higher education, a regenerative clan culture would likely be the most conducive to ensuring a culture of high academic quality. The case study of UNISA indicates that all the functional quality apparatus is in place with supporting evidence, but that more attention could be paid to the meaningful enactment of a quality culture in in all of the above loci and levels.

Originality/value
This paper makes a conceptual contribution to developing the concept “quality culture” to include meaning making, communities of practice and ultimately communal, rather than only individual, webs of significance. The paper identifies loci and levels of quality and quality cultures and explores what may count as evidence of high quality in a distance-education setting.
Placing emotion and fantasy at the heart of the researcher-researched relationship
Authors: Gabriel Yiannis 
Published: July 2019

Purpose
The purpose of this paper is to introduce psychosocial research methodology as a method that makes use of the emotions of researcher and researched and goes well-beyond empathetic understanding.

Design/methodology/approach
This short piece critically introduces the recently published book Further Researching Beneath the Surface (Volume 2): Psycho-social Research Methods in Practice, Eds Cummins, A.-M., and Williams, N., and analyses the psychosocial approach to qualitative research that emphasizes research as an emotional activity and makes use of the researcher’s and the researched’s emotional responses to each other in drawing interpretations about organizational phenomena.

Findings
By analysing transference and counter-transference, researchers can draw valuable insights into organizational phenomena that remain unseen by more conventional research methodologies.

Originality/value
Emotions, far from being the enemy of the researcher, can, if recognized properly, be valuable resources in social research.
Changing the nature of organizational change
Authors: Kirby Deborah 
Published: July 2019

Purpose
Although organizational change management has become a permanent practice, failure thrives at a rate of 50 per cent to 75 per cent and has done so for nearly 40 years. Executives and consultants continue to plow the same path of “change,” sowing the same seeds, yet somehow expecting a different crop to grow; it is not for a lack of good intention or sincere effort to improve the organization. This paper is meant to challenge and inspire researchers, consultants and particularly organizational leaders and members toward liberating themselves from fixed ways of thinking to reimagine change as natural and ongoing rather than episodic – essential in an era of constant flux.

Design/methodology/approach
A critical analysis of wide-ranging literature related to the genesis of the organization, organization theory, culture, metaphor and change revealed four unfavorable conditions, making attempts at sustainable change nearly impossible.

Findings
An organization’s unconscious and habitual thought-action patterns considerably contribute to creating four unfavorable conditions for change. Understanding this context is essential before initiating change efforts. Reorienting change from an analytical to a relational paradigm and disrupting linear, prescriptive thinking makes way for emergent, cooperative and inclusive efforts to induce sustainable, transformational change.

Originality/value
This research sheds a different light on what makes sustainable organizational change elusive and offers strategic human resource managers a new perspective on the nature of change.
Modeling Flow, Nutrient, and Sediment Delivery from a Large International Watershed Using a Field‐Scale SWAT Model
Authors: Dagnew Awoke , Scavia Donald , Wang Yu‐Chen , Muenich Rebecca , Long Colleen , Kalcic Margaret 
Published: July 2019

AbstractA large international watershed, the St. Clair‐Detroit River System, containing both extensive urban and agricultural areas, was modeled using the Soil and Water Assessment Tool (SWAT) model. The watershed, located in southeastern Michigan, United States, and southwestern Ontario, Canada, encompasses the St. Clair, Clinton, Detroit (DT), Sydenham (SY), Upper, and Lower Thames subwatersheds. The SWAT input data and model resolution (i.e., hydrologic response units, HRUs), were established to mimic farm boundaries, the first time this has been done for a watershed of this size. The model was calibrated (2007–2015) and validated (2001–2006) with a mix of manual and automatic methods at six locations for flow and water quality at various time scales. The model was evaluated using Nash–Sutcliffe efficiency and percent bias and was used to explore major water quality issues. We showed the importance of allowing key parameters to vary among subwatersheds to improve goodness of fit, and the resulting parameters were consistent with subwatershed characteristics. Agricultural sources in the Thames and SY subwatersheds and point sources from DT subwatershed were major contributors of phosphorus. Spatial distribution of phosphorus yields at HRU and subbasin levels identified locations for potential management targeting for both point and nonpoint sources and revealed that in some subwatersheds nonpoint sources are dominated by urban sources.
Prevalence of resolved paracentral acute middle maculopathy lesions in fellow eyes of patients with unilateral retinal vein occlusion
Authors: Maltsev Dmitrii S. , Kulikov Alexei N. , Burnasheva Maria A. , Chhablani Jay 
Published: July 2019

AbstractPurposeTo study the prevalence of resolved paracentral acute middle maculopathy (PAMM) lesions in fellow eyes of patients with unilateral retinal vein occlusion (RVO) and eyes of healthy individuals.MethodsThis case–control observational study took place in a referral university medical centre. Forty‐five (17 males, 28 females, 64.7 ± 10.8 years) patients with branch retinal vein occlusion (BRVO), 21 (17 males, 4 females, 68.8 ± 11.2 years) patients with central retinal vein occlusion (CRVO) and 57 healthy individuals (25 males, 32 females, 67.4 ± 10.5 years) were included. Presence of resolved PAMM lesions was evaluated by reviewing cross‐sectional scans of 8‐mm optical coherence tomography angiography protocol. Resolved PAMM lesion was defined as inner nuclear layer thinning with outer plexiform layer elevation.ResultsResolved PAMM lesions were found in 32/45 (71.1%) and 15/21 (71.4%) of BRVO and CRVO patients, respectively. In healthy volunteers, resolved PAMM lesions were found in 11/57 (19.3%) individuals with bilateral involvement in 8 individuals (72.7%). RVO patients demonstrated the presence of resolved PAMM lesions in fellow eye significantly more frequently than healthy individuals (odds ratio (OR) 10.6, p < 0.001, 95% CI 4.5–24.6). OR for the presence of large resolved PAMM lesions in BRVO patients and CRVO patients versus healthy individual was 12.1 (p = 0.02, 95% CI 1.5–100.9) and 22.4 (p = 0.005, 95% CI 2.5–200.6), respectively.ConclusionResolved PAMM lesions defined as inner nuclear layer thinning associated with outer plexiform layer elevation are highly prevalent in fellow eyes of patients with unilateral RVO. Resolved PAMM lesions may have an association with RVO.
What role do comprehension‐oriented learning strategies have in solving math calculation and word problems at the end of middle school?
Authors: Kikas Eve , Mädamürk Kaja , Palu Anu 
Published: July 2019

BackgroundMath is a difficult subject with which many upper middle‐school students struggle. In addition to knowledge, skills, and motivation, effective learning strategies play an important role in learning math.AimsThis study aimed to examine the effects of comprehension‐oriented learning strategies (perceptual and abstract grouping of material) – together with math self‐concept, task‐persistent learning behaviour, earlier math skills, reasoning abilities, and reading comprehension – on solving mathematical calculation and word problems at the end of middle school.SampleThe sample consisted of 231 students (50% boys; mean age in Grade 9 = 15.55 years) from 16 schools and 31 classrooms in Estonia.MethodsStudents were tested twice – once at the end of Grade 6 and once at the end of Grade 9. Calculation and problem‐solving skills were assessed at both time points. Math self‐concept, teacher‐rated task persistence, reasoning abilities, and reading comprehension were assessed in Grade 6. Learning strategies were assessed using a word‐memorization task in Grade 9. Multiple regression analysis was used.Results and ConclusionsApplying abstract (but not perceptual) grouping was related to higher calculation and problem‐solving skills. Math skills were persistent over time, and calculation and problem‐solving skills mutually affected each other. Math self‐concept, task persistence, and reading comprehension had a positive effect on problem‐solving but not calculation skills. The study noted deficient use of comprehension‐oriented strategies at the end of middle school, suggesting that more attention should be paid to teaching and discussing such learning strategies. These findings suggest that students’ math skills may be enhanced by supporting metacognitive awareness and use of comprehension‐oriented learning strategies.
Writing as ‘Compearance’ in Diário da Queda by Michel Laub
Authors: Baker Emily Mary 
Published: July 2019

Diário da Queda (2011) by Michel Laub has been described as autoficção (autofiction), the Brazilian translation of the concept coined by Serge Doubrovsky to describe the narrative working‐through of trauma through fictional autobiography. This article re‐examines the definition of ‘autofiction’ and argues that Laub's narrative process more closely resembles Jean‐Luc Nancy's notion of a singular voice ‘compearing’ experiences in a process of ‘sharing’ that, when combined with touch and affection can – according to the novel – more successfully help to overcome trauma. At stake are questions regarding the inheritance of Holocaust memory, as well as its politicised deployment in contemporary conflicts.
Identification of prognostic markers in diffuse midline gliomas H3K27M‐mutant
Authors: Dufour Charlotte , Perbet Romain , Leblond Pierre , Vasseur Romain , Stechly Laurence , Pierache Adeline , Reyns Nicolas , Touzet Gustavo , Le Rhun Emilie , Vinchon Matthieu , Maurage Claude‐Alain , Escande Fabienne , Renaud Florence 
Published: July 2019

AbstractPediatric diffuse midline gliomas are devastating diseases. Among them, diffuse midline gliomas H3K27M‐mutant are associated with worse prognosis. However, recent studies have highlighted significant differences in clinical behavior and biological alterations within this specific subgroup. In this context, simple markers are needed to refine the prognosis of diffuse midline gliomas H3K27M‐mutant and guide the clinical management of patients. The aims of this study were (i) to describe the molecular, immunohistochemical and, especially, chromosomal features of a cohort of diffuse midline gliomas and (ii) to focus on H3K27M‐mutant tumors to identify new prognostic markers. Patients were retrospectively selected from 2001 to 2017. Tumor samples were analyzed by immunohistochemistry (including H3K27me3, EGFR, c‐MET and p53), next‐generation sequencing and comparative genomic hybridization array. Forty‐nine patients were included in the study. The median age at diagnosis was 9 years, and the median overall survival (OS) was 9.4 months. H3F3A or HIST1H3B mutations were identified in 80% of the samples. Within the H3K27M‐mutant tumors, PDGFRA amplification, loss of 17p and a complex chromosomal profile were significantly associated with worse survival. Three prognostic markers were identified in diffuse midline gliomas H3K27M‐mutant: PDGFRA amplification, loss of 17p and a complex chromosomal profile. These markers are easy to detect in daily practice and should be considered to refine the prognosis of this entity.
Pharmacological basis and new insights of resveratrol action in the cardiovascular system
Authors: Cheng Chak Kwong , Luo Jiang‐Yun , Lau Chi Wai , Chen Zhen‐Yu , Tian Xiao Yu , Huang Yu 
Published: July 2019

Resveratrol (trans‐3,4′,5‐trihydroxystilbene) belongs to the family of natural phytoalexins. Resveratrol first came to our attention in 1992, following reports of the cardioprotective effects of red wine. Thereafter, resveratrol was shown to exert antioxidant, anti‐inflammatory, anti‐proliferative, and angio‐regulatory effects against atherosclerosis, ischaemia, and cardiomyopathy. This article critically reviews the current findings on the molecular basis of resveratrol‐mediated cardiovascular benefits, summarizing the broad effects of resveratrol on longevity regulation, energy metabolism, stress resistance, exercise mimetics, circadian clock, and microbiota composition. In addition, this article also provides an update, both preclinically and clinically, on resveratrol‐induced cardiovascular protection and discusses the adverse and inconsistent effects of resveratrol reported in both preclinical and clinical studies. Although resveratrol has been claimed as a master anti‐aging agent against several age‐associated diseases, further detailed mechanistic investigation is still required to thoroughly unravel the therapeutic value of resveratrol against cardiovascular diseases at different stages of disease development.Linked ArticlesThis article is part of a themed section on The Pharmacology of Nutraceuticals. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v177.6/issuetoc
Effect of the novel histamine H4 receptor antagonist SENS‐111 on spontaneous nystagmus in a rat model of acute unilateral vestibular loss
Authors: Petremann Mathieu , Gueguen Cindy , Delgado Betancourt Viviana , Wersinger Eric , Dyhrfjeld‐Johnsen Jonas 
Published: July 2019

Background and PurposeHistamine H4 receptors are expressed in the peripheral vestibular system, and their selective inhibition improves vertigo symptoms in rats with unilateral vestibular lesions. The effects of SENS‐111, a selective oral H4 receptor antagonist with high affinity to both animal and human receptors, on vertigo symptoms was evaluated in a translational in vivo model of unilateral vestibular loss.Experimental ApproachPharmacokinetics of SENS‐111 in rats was determined to aid dose selection for efficacy testing. Vestibular lesions were induced in rats by unilateral transtympanic injection of kainic acid. The effect of SENS‐111 (10 or 20 mg·kg−1) on spontaneous nystagmus was evaluated compared with placebo vehicle using video‐nystagmography, and the effective dose was compared with those of similar drugs used clinically, as single agents or combined with SENS‐111.Key ResultsDoses were selected for plasma exposure were consistent with published phase 1 results from healthy volunteers. SENS‐111 of 10 mg·kg−1 gave a 21–22% reduction in nystagmus at 1 hr post‐administration, whereas a loss of efficacy was seen with 20 mg·kg−1. Compared with SENS‐111, meclizine and methylprednisolone had minimal effects on nystagmus as single agents, and meclizine abolished the effect of SENS‐111 when combined with SENS‐111. All evaluated drugs were well tolerated.Conclusions and ImplicationsThe exposure‐efficacy relationship for improved spontaneous nystagmus seen with SENS‐111 in this in vivo model is consistent with phase 1 clinical results and provides preclinical support for pharmacokinetic/pharmacodynamic modelling and selection of effective clinical drug concentrations.Linked ArticlesThis article is part of a themed section on New Uses for 21st Century. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v177.3/issuetoc
Modulation of μ‐opioid receptor activation by acidic pH is dependent on ligand structure and an ionizable amino acid residue
Authors: Meyer Johanna , Del Vecchio Giovanna , Seitz Viola , Massaly Nicolas , Stein Christoph 
Published: July 2019

Background and PurposeAdverse side effects of conventional opioids can be avoided if ligands selectively activate peripheral opioid receptors in injured tissue. Injury and inflammation are typically accompanied by acidification. In this study, we examined influences of low pH and mutation of the ionizable amino acid residue H2976.52 on μ‐opioid receptor binding and signalling induced by the μ‐opioid receptor ligands fentanyl, DAMGO, and naloxone.Experimental ApproachHEK 293 cells stably transfected with μ‐opioid receptors were used to study opioid ligand binding, [35S]‐GTPγS binding, and cAMP reduction at physiological and acidic pH. We used μ‐opioid receptors mutated at H2976.52 to A (MOR‐H2976.52A) to delineate ligand‐specific interactions with H2976.52.Key ResultsLow pH and the mutant receptor MOR‐H2976.52A impaired naloxone binding and antagonism of cAMP reduction. In addition, DAMGO binding and G‐protein activation were decreased under these conditions. Fentanyl‐induced signalling was not influenced by pH and largely independent of H2976.52.Conclusions and ImplicationsOur investigations indicate that low pH selectively impairs μ‐opioid receptor signalling modulated by ligands capable of forming hydrogen bonds with H2976.52. We propose that protonation of H2976.52 at acidic pH reduces binding and subsequent signalling of such ligands. Novel agonists targeting opioid receptors in injured tissue might benefit from lack of hydrogen bond formation with H2976.52.