bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN PRAKTIK TEOLOGI JABARIYAH DENGAN KEMISKINAN PADA NELAYAN DI KUALA LANGSA ACEH
Authors: Nasution ISMAIL FAHMI Arrauf 
Published: May 2018

Artikel ini menggambarkan hubungan antara praktik teologi Jabariyah dan relevansinya dengan kemiskinan di Kuala Langsa, Aceh. Dalam ajaran Islam teologi merupakan sisi fundamental dalam beragama. Aplikasi beragama dalam dimensi empirik merupakan manifestasi dari pemahaman manusia terhadap kehendak Tuhan. Di dalam Islam, manusia dituntut untuk aktif mengembangkan potensi diri serta berupaya mengubah nasib. Namun faktanya, nelayan Kuala Langsa yang menjalankan agama berada di garis kemiskinan. Untuk itu, artikel ini mencari hubungan antara konsep teologi Jabariyah dengan tingkat kemiskinan di Kuala Langsa. Penelitian menggunakan pendekatan fungsional dalam melihat gejala beragama masyarkat. Peneliti mengobservasi keseharian praktik ekonomi dan beragama nelayan Kuala Langsa. Selain itu, peneliti mewawancarai juga nelayan Kuala Langsa untuk mengetahui tingkat pemahaman teologi. Hasilnya didapatkan hubungan antara pemahaman Jabariyah nelayan Kuala Langsa dengan kemiskinan di Kuala Langsa. Terdapat pemahaman fatalistik yang kuat pada nelayan Kuala langsa dalam memahami konsep takdir dan kemampuan manusia dalam berusaha.
Kata Kunci: Teologi, Jabariyah, Kemiskinan, Aceh
Clarence Glacken: Pioneer Environmental Historian
Authors: Rajan S. Ravi 
Published: May 2018

Abstract
Clarence Glacken's magnum opus Traces on the Rhodian Shore, first published in 1967, was an intellectual history about ideas of nature and culture from ancient Greece to the end of the eighteenth century. The Professional Geographer called it 'One of the best and most important books published by a geographer in the English-speaking world in the last hundred years'. Traces remains in print five decades after its initial publication, and is regarded as one of the foundational classics in the field of environmental history. Glacken himself is considered a path breaker in the discipline and is read widely by environmental historians. Little, however, is known about this pioneering scholar and especially, that he was prolific in his later years, having written an unpublished (and lost) sequel to Traces, and a full draft of another book. Drawing extensively upon the Glacken archives at the Bancroft Library at UC Berkeley, this paper describes his intellectual evolution as a scholar, and explores his contributions to the field of environmental history.
Sixty Earth-Days Test of a Prototype Pt/HTCC Alumina Package in Simulated Venus Environment
Authors: Chen Liangyu , Neudeck Philip G. , Meredith Roger D. , Lukco Dorothy , Spry David J. , Nakley Leah M. , Phillips Kyle G. , Beheim Glenn M. , Hunter Gary W. 
Published: May 2018

Abstract
This paper presents experimental results of a prototype high temperature co-fired ceramic (HTCC) package with Au/Pt metallization in a three-phase harsh environment test that culminated with 60-day demonstration in simulated Venus surface environment of 465 °C with corrosive atmosphere at 90 bar pressure. The prototype package is based on previously developed and reported HTCC package successfully tested with multiple analog and digital silicon carbide (SiC) high temperatures semiconductor integrated circuits (ICs) at NASA Glenn Research Center in 500 °C Earth air ambient for over ten thousands hours, and short-term tested at temperatures above 800 °C. The three-phase harsh environment test started with 48 hours in 465 °C Earth air, followed by 48 hours in 465 °C nitrogen at 90 bar pressure and 1400 hours in simulated Venus surface environment of 465 °C with corrosive atmosphere at 90 bar. Initial analytical results of the package materials and surfaces after exposure to Venus environment are discussed to assess the stability of the packaging materials in the tested environments. The test in simulated Venus environment was implemented in the NASA Glenn Extreme Environment Rig (GEER). The results of this study suggest that an effective encapsulation of areas of surface metallization and vicinities may help to improve electrical performance of a HTCC alumina packaging system in Venus environment.
Modelling the Influence of Conformal Coatings on Thermo-Mechanical Fatigue of Solder Interconnects in Electronic Packages
Authors: Serebreni Maxim , Wilcoxon Ross , McCluskey F. Patrick 
Published: May 2018

Abstract
Protecting electronic components at harsh environments and applications often requires the use of conformal coatings, underfills or potting compounds. The temperature dependent properties of these materials greatly depend on their chemical formulation. Conformal coatings used for electronic applications are available in a variety of materials ranging from silicones, acrylics, polyurethanes, paralyne and epoxies. The glass transition temperature (Tg) varies for each material and represents a phase change from a hard glassy one to a soft rubbery state. Temperature fluctuations experienced by electronics can span a wide range that can often include the Tg of the encapsulant.
In this paper, thermal cycling simulations are performed on QFN and BGA components using different conformal coating materials. Material characterization is performed to determine the temperature dependent properties of several conformal coating materials. Results illustrate higher damage accumulation during ramp down and cold side of thermal cycles. Information obtained in this study is used to develop a mitigation strategy that enables selection of encapsulants without compromising desired system level encapsulation method to increase overall board level reliability.
Injectivity of the Connecting Homomorphisms in Inductive Limits of Elliott–Thomsen Algebras
Authors: Liu Zhichao 
Published: May 2018

AbstractLet$A$be the inductive limit of a sequence$$\begin{eqnarray}A_{1}\xrightarrow[{}]{\unicode[STIX]{x1D719}_{1,2}}A_{2}\xrightarrow[{}]{\unicode[STIX]{x1D719}_{2,3}}A_{3}\longrightarrow \cdots\end{eqnarray}$$with$A_{n}=\bigoplus _{i=1}^{n_{i}}A_{[n,i]}$, where all the$A_{[n,i]}$are Elliott–Thomsen algebras and$\unicode[STIX]{x1D719}_{n,n+1}$are homomorphisms. In this paper, we will prove that$A$can be written as another inductive limit$$\begin{eqnarray}B_{1}\xrightarrow[{}]{\unicode[STIX]{x1D713}_{1,2}}B_{2}\xrightarrow[{}]{\unicode[STIX]{x1D713}_{2,3}}B_{3}\longrightarrow \cdots\end{eqnarray}$$with$B_{n}=\bigoplus _{i=1}^{n_{i}^{\prime }}B_{[n,i]^{\prime }}$, where all the$B_{[n,i]^{\prime }}$are Elliott–Thomsen algebras and with the extra condition that all the$\unicode[STIX]{x1D713}_{n,n+1}$are injective.
Vinorelbine in advanced non-small-cell lung cancer: Has a survival benefit been achieved in clinical practice?
Authors: Street Lesley E. , Chambers Carole R. 
Published: May 2018

<p>ABSTRACT</p><p>Purpose: Vinorelbine used in conjunction with cisplatin in advanced, inoperable non-small-cell lung cancer has been linked to a survival advantage in this otherwise terminal disease. Survival outcomes achieved in clinical trials, however, may not be matched in practice thus necessitating this practical evaluation.</p><p>Methods: A provincial evaluation of all patients treated with this regimen from September 1994 to July 1996 was conducted by chart review. Survival data was analyzed by the Kaplan-Meier methodology.</p><p>Results: The median survival time and survival rate observed in this practical evaluation was comparable to that achieved in an earlier clinical trial. A paradoxical trend between lower dose intensity of both vinorelbine and cisplatin and improved survival was noted (p&lt;0.0005). Hematological toxicity was common.</p><p>Conclusion: A survival advantage of vinorelbine and cisplatin in this population when compared with best supportive care was observed.Further investigations of different doses and schedules as well as quality of life assessments would complement the finding of this study.</p><p> RÉSUMÉ</p><p>Objectif : L'administration conjointe de vinorelbine et de cisplatine dans les cas de cancer du poumon à grandes cellules inopérable a été associée à une meilleure survie clans ces cas de maladie autrement fatale. Cependant, ces avantages au plan de la de survie observés lors des essais cliniques pourraient ne pas être reproductibles dans la pratique. C'est pourquoi cette évaluation pratique est nécessaire.</p><p>Méthode : Une évaluation de tous les patients traités par cette association médicamenteuse de septembre 1994 à juillet 1996 a été menée dans la province, à partir de l'analyse des dossiers médicaux des patients. Les données sur la survie ont été analysées au moyen de la méthode de Kaplan-Meyer.</p><p>Résultats : Le temps de survie et le taux de survie moyens notés au cours de cette évaluation pratique étaient comparables à ceux observés lors des essais cliniques antérieurs. Une tendance paradoxale entre de faibles doses de vinorelbine et de cisplatine et une amélioration de la survie a été notée (p &lt; 0,0005). L'hématotoxicité était courante.</p><p>Conclusion : On a remarqué un avantage au plan de la survie avec l'administration conjointe de vinorelbine et de cisplatine dans cette population, en comparaison aux meilleurs soins de soutien. Des études de doses et de schémas posologiques plus poussées el des évaluations de la qualité de vie viendraient compléter les résultats de cette étude.</p>
Samba e religião presença e resistência na cidade de São Paulo. *
Authors: Brito Ênio José da Costa 
Published: May 2018

Esta Comunicação visa uma análise crítica de uma tese e uma dissertação, que tem como objetos o samba e a religião afro na cidade de São Paulo. Ambas consideram o samba e a religião como manifestações e expressões culturais através das quais as populações negras em afro-diáspora refizeram e reatualizaram memórias por meio de religiosidades, ritmos, danças e performances.
Nivel de actividad física habitual en escolares de 13 años de España e India. Un estudio transcultural
Authors: López Sánchez G.F. , Ahmed Md. D. , Díaz Suárez A. 
Published: May 2018

<p>El nivel de actividad física de las personas es muy importante a nivel internacional. El objetivo de este estudio fue analizar el nivel de actividad física habitual de escolares de India y España. Para lograr este objetivo, se utilizó el cuestionario PACE (Physician-based Assessment and Counseling for Exercise). Este cuestionario valora con dos preguntas cuántos días en la última semana (PACE 1) y en una semana habitual (PACE 2) el sujeto realiza al menos 60 minutos de actividad física. La muestra del estudio estuvo compuesta por 154 adolescentes de 13 años de edad. Del total de la muestra, 61 adolescentes (36 hombres, 59%, y 25 mujeres, 41%) eran de Nagaon, Assam (India), y 93 adolescentes (39 hombres, 42%, y 54 mujeres, 58%) eran de la Región de Murcia (España). Los resultados mostraron que los adolescentes de 13 años de España e India no realizan suficiente actividad física, según las recomendaciones de la OMS. El 80.5% de los adolescentes españoles y el 76% de los adolescentes indios de la muestra fueron inactivos, según la clasificación del cuestionario PACE. Por tanto, se sugiere llevar a cabo programas de intervención para aumentar el nivel de actividad física en ambos países. </p>
Breast fibroblasts in both cancer and normal tissues induce phenotypic transformation of breast cancer stem cells: a preliminary study
Authors: Wang Bixiao , Xi Chunfang , Liu Mingwei , Sun Haichen , Liu Shuang , Song Lei , Kang Hua 
Published: May 2018

Background
Breast cancer stem cells (BCSCs) are associated with the invasion of breast cancer. In recent years, studies have demonstrated different phenotypes among BCSCs. Furthermore, BCSCs of diverse phenotypes are present at different tumour sites and different histological stages. Fibroblasts are involved in the phenotypic transformation of BCSCs. Cancer-associated fibroblasts (CAFs) participate in the induction of epithelial–mesenchymal transition, thereby promoting the acquisition of stem cell characteristics, but little is known about the role of normal fibroblasts (NFs) in the phenotypic transformation of BCSCs or about the effect of CAFs and NFs on BCSC phenotypes.

Methods
A total of six pairs of primary CAFs and NFs were isolated from surgical samples of breast cancer patients and subjected to morphological, immunohistochemical, cell invasion and proteomics analyses. After establishing a cell culture system with conditioned medium from CAFs and NFs, we used the mammosphere formation assay to explore the effect of CAFs and NFs on the self-renewal ability of BCSCs. The effect of CAFs and NFs on the phenotypic differentiation of BCSCs was further analysed by flow cytometry and immunofluorescence.

Results
The isolated CAFs and NFs did not show significant differences in cell morphology or alpha-smooth muscle actin (α-SMA) expression, but cell invasion and proteomics analyses demonstrated heterogeneity among these fibroblasts. Both CAFs and NFs could promote the generation of BCSCs, but CAFs displayed a greater ability than NFs in promoting mammosphere formation. Conditioned medium from CAFs increased the proportion of aldehyde dehydrogenase-1 positive (ALDH1+) BCSCs, but conditioned medium from NFs was more likely to promote the generation of CD44+CD24− BCSCs from MCF-7 cells.

Discussion
This study validated the heterogeneity among CAFs and NFs and expanded on the conclusion that fibroblasts promote the generation of cancer stem cells. Our results particularly emphasized the effect of NFs on the phenotypic transformation of BCSCs. In addition, this study further highlighted the roles of CAFs and NFs in the induction of different phenotypes in BCSCs.
CAR T Cells and T-Cell Therapies for Cancer
Authors: Brudno Jennifer N. , Maus Marcela V. , Hinrichs Christian S. 
Published: November 2024

ImportanceChimeric antigen receptor (CAR) T cells are T lymphocytes that are genetically engineered to express a synthetic receptor that recognizes a tumor cell surface antigen and causes the T cell to kill the tumor cell. CAR T treatments improve overall survival for patients with large B-cell lymphoma and progression-free survival for patients with multiple myeloma.ObservationsSix CAR T-cell products are approved by the US Food and Drug Administration (FDA) for 6 hematologic malignancies: B-cell acute lymphoblastic leukemia, large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, chronic lymphocytic leukemia, and multiple myeloma. Compared with standard chemotherapy followed by stem cell transplant, CAR T cells improved 4-year overall survival in patients with large B-cell lymphoma (54.6% vs 46.0%). Patients with pediatric acute lymphoblastic leukemia achieved durable remission after CAR T-cell therapy. At 3-year follow-up, 48% of patients were alive and relapse free. In people with multiple myeloma treated previously with 1 to 4 types of non–CAR T-cell therapy, CAR T-cell therapy prolonged treatment-free remissions compared with standard treatments (in 1 trial, CAR T-cell therapy was associated with progression-free survival of 13.3 months compared with 4.4 months with standard therapy). CAR T-cell therapy is associated with reversible acute toxicities, such as cytokine release syndrome in approximately 40% to 95% of patients, and neurologic disorders in approximately 15% to 65%. New CAR T-cell therapies in development aim to increase efficacy, decrease adverse effects, and treat other types of cancer. No CAR T-cell therapies are FDA approved for solid tumors, but recently, 2 other T lymphocyte–based treatments gained approvals: 1 for melanoma and 1 for synovial cell sarcoma. Additional cellular therapies have attained responses for certain solid tumors, including pediatric neuroblastoma, synovial cell sarcoma, melanoma, and human papillomavirus–associated cancers. A common adverse effect occurring with these T lymphocyte–based therapies is capillary leak syndrome, which is characterized by fluid retention, pulmonary edema, and kidney dysfunction.Conclusions and RelevanceCAR T-cell therapy is an FDA-approved therapy that has improved progression-free survival for multiple myeloma, improved overall survival for large B-cell lymphoma, and attained high rates of cancer remission for other hematologic malignancies such as acute lymphoblastic leukemia, follicular lymphoma, and mantle cell lymphoma. Recently approved T lymphocyte–based therapies demonstrated the potential for improved outcomes in solid tumor malignancies.
US Cancer Mortality Trends Among Asian and Pacific Islander Populations
Authors: Zhu David T. , Pompa Isabella R. , Qi David , Goldberg Saveli I. , Lee Richard J. , Kamran Sophia C. 
Published: November 2024

ImportanceCancer is the leading cause of death among Asian American individuals and the second leading cause of death among Native Hawaiian and Pacific Islander people.ObjectiveTo evaluate longitudinal cancer mortality trends from 1999 to 2020 among Asian American and Pacific Islander populations in the US by demographic characteristics.Design, Setting, and ParticipantsThis cross-sectional study used the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database to obtain age-adjusted cancer death rates among Asian American and Pacific Islander individuals of all ages between January 1, 1999, and December 31, 2020. Data were analyzed from January 12 to March 19, 2024.ExposuresAge, sex, cancer type, and US census regions.Main Outcomes and MeasuresTrends and average annual percent changes (AAPCs) in age-adjusted cancer-specific mortality (CSM) rates for non-Hispanic Asian American and Pacific Islander populations were estimated by cancer type, age, sex, and region using Joinpoint regression.ResultsBetween 1999 and 2020, 305 386 Asian American and Pacific Islander individuals (median [IQR] age, 69.5 [58.5-79.2] years; 51.1% male) died of cancer in the US. Overall, the CSM rate decreased by 1.5% annually. Men experienced a greater CSM rate decrease (AAPC, −1.8%; 95% CI, −2.2% to −1.3%) compared with women (AAPC, −1.1%; 95% CI: −1.2% to −1.0%). For women, death rates decreased for most cancer types but increased for uterine (AAPC, 2.5%; 95% CI, 2.0%-3.0%) and brain and central nervous system (AAPC, 1.4%; 95% CI: 0.7%-2.1%) cancers. Colorectal cancer mortality rates increased among men aged 45 to 54 years (AAPC, 1.3%; 95% CI, 0.5%-2.1%). Liver and intrahepatic bile duct cancer mortality increased for both men and women in all US census regions, uterine cancer mortality increased in all regions for women, and pancreatic cancer mortality increased in the Midwest for both men and women.Conclusions and RelevanceAlthough these findings show an overall decrease in CSM among Asian American and Pacific Islander populations, specific cancer types exhibited increased mortality rates, with further disparities by sex and age. Targeted, culturally adapted clinical and public health interventions are needed to narrow disparities in cancer mortality.
Virulence‐Free Reconstituted Synthetic Nanopathogen Empowered by Timely‐Activating TLR Agonist Promotes Heterologous Cancer Immunotherapy with Depletion of Tumor‐Specific Treg Cells
Authors: Lee Sang Nam , Park Sei Hyun , Choi Jin‐Ho , Heo Jang Hun , Lee Min‐Ho , Oh Sang‐Seok , Noh Young‐Woock , Lim Yong Taik 
Published: November 2024

AbstractThe heterologous immunity of live pathogens leads to the emergence of this approach as a pivotal component in cancer immunotherapy. However, virulence, inflammatory‐related toxicity, and the induction of Treg cells after treatment hinder their clinical translation. Here, to exploit the heterologous immunity of live pathogens without risks, a virulence‐free reconstituted synthetic nanopathogen (RSnP) is developed by the cell wall skeleton of disrupted Mycobacterium bovis and the incorporation of timely‐activating Toll‐like receptor 7/8 agonists of which multifaceted activities can be promoted by endolysosomal enzymes. Immunization with RSnP, even without tumor‐specific antigens, exhibits potent antitumor efficacy against melanoma, breast cancer, and bladder cancer by promoting antitumor effector cells (CD8+ T cells, NK cells, M1 macrophages, and Th17 cells) and proinflammatory cytokines (IL‐12p70, TNF‐α, and IL‐6) while simultaneously mitigating immunosuppressive myeloid cells (MDSCs and M2 macrophages) in the tumor microenvironment, surpassing the therapeutic efficacies of approved live‐BCG drug and mRNA vaccine. The increase in CCR8+Foxp3+ Treg cells induced to counteract RSnP treatment can be attenuated by anti‐CCR8 antibody, a depletion antibody for tumor‐specific Treg cells, to synergize therapeutic efficacy with relieved autoimmunity. RSnP can be a therapeutic nanomedicine platform across heterologous cancers and emerging infectious virus variants with minimized toxicity.
A Novel B2 Precipitate Gives High Strength and High Impact Toughness to Bcc‐Structured Cryogenic Steels
Authors: Chen Qiyuan , Tang Shuai , Zhang Weina , Yan Haile , Sha Gang , Cao Guangming , Chen Jun , Xie Zhanglong , Jin Shenbao , Wang Xiaonan , Li Linlin , Zhang Zhongwu , Huang Mingxin , van der Zwaag Sybrand , Liu Zhenyu 
Published: November 2024

AbstractFor decades, solid solution strengthening with up to 9 wt.% Ni has been the only successful strategy to obtain high strength and high impact toughness in bcc‐structured (ferritic or tempered martensitic) cryogenic steels. Until now coherent nano‐precipitates, an effective strengthening agent at room temperature, cannot be used to improve properties at cryogenic temperatures. Here, a new type of Mo‐rich nano‐B2 precipitates formed in a 6.5 wt.% Ni steel upon doping with 0.2 wt.% of Mo is reported. These precipitates are not only fully coherent with the matrix but are also shearable at 77 K. A high precipitate number density in excess of 2 × 1024 m−3 has been achieved by an industrially feasible process optimization, which brings both the cryogenic strength and impact toughness of the steel to the same levels as those of 9Ni steels. The Mo‐rich B2 precipitation strengthening, therefore, opens a new avenue for the design and development of low‐cost high‐performance cryogenic steels.
Multi‐Scenario Applications of Multi‐Dimensional Yarn‐Based Wearable Integrated Sensors
Authors: Ma Qiancheng , Zhang Zhaofa , Zhang Dongyang , Tian Wei 
Published: November 2024

Abstract1D yarn sensors, crucial for smart textiles, face challenges in achieving diverse functionalities, multiple applications, and durability in harsh environments. Herein, a simple strategy is proposed to prepare reduced graphene oxide‐polyimide yarns (rGO‐PYs), constructing functional and multi‐dimensional sensors for multi‐scenario applications. rGO‐PYs can detect multiple mechanical stimuli, and exhibit a broad bending and pressure response range (0°–180° and 0.12–62.39 KPa), quick response and recovery time (both <100 ms), and excellent cyclic stability. It features real‐time monitoring of human activities, such as joint movements, speech, writing, respiratory, pulse, and heart rate. rGO‐PYs exhibit a remarkable resilience to harsh environments, whether in liquid nitrogen (−196 °C), high temperature (300 °C), acid, or base. Crucially, expanded into an integrated 2D fabric, rGO‐PYs maintain their exceptional multi‐dimensional sensing. The point contact pressure sensor (PCPS) and pressure sensing array showed remarkable sensing performance in identifying pressure and its distribution. This work establishes a comprehensive system from preparation to application, encompassing 1D yarns large‐scale fabrication, functional sensing validation, integration into multi‐dimensional sensors, and diverse cross‐scenario applications. The innovative system would transform traditional yarns into intelligent fabrics, further advancing functional yarns into multi‐dimensional sensors (1D to 2D and 3D), enabling their diverse multi‐scenario applications.