bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH SUBSTITUSI ALPUKAT (Persea Americana Mill) DAN TEPUNG IKAN LELE (Clarias gariepinus Burchell) TERHADAP MUTU ORGANOLEPTIK DAN KADAR PROTEIN PADA BISKUIT MPASI
Authors: Asmira Sepni , Nova Maria , Hanum Dzulfa 
Published: June 2019

Masalah gizi kurang pada bayi dan anak-anak dapat menyebabkan terganggunya pertumbuhan dan perkembangan anak. Untuk mengatasinya perlu perbaikan pola makan masyarakat melalui diversifikasi dan substitusi pangan. Alpukat dan ikan lele merupakan bahan pangan potensial pada pembuatan biskuit kaya akan protein. Tujuan penelitian ini adalah untuk mengetahui pengaruh substitusi alpukat dan tepung ikan lele terhadap kadar protein dan mutu organoleptik pada biskuit. Penelitian eksperimental ini menggunakan desain rancangan acak lengkap (RAL) yang terdiri dari tiga perlakuan dan dua kali ulangan. Pengamatan yang dilakukan adalah uji subjektif yang dilakukan terhadap cita rasa (uji organoleptik) dengan 25 panelis agak terlatih dan analisis protein menggunakan metode Kjedahl berdasarkan SNI 01-2891-1992. Data dianalisis statistik dengan menggunakana SPSS 16. Hasil uji organoleptik didapatkan perlakuan yang paling disukai adalah perlakuan B (10 g alpukat: 20 g tepung ikan lele) dengan indikator penilaian berdasarkan kesukaan terhadap warna, tekstur, aroma serta rasa. Hasil kadar protein terbaik adalah pada perlakuan A (5 g alpukat: 25 g tepung ikan lele) yaitu sebesar 12,37 % , seluruh biskuit dengan ketiga perlakuan telah memenuhi kriteria biskuit MPASI berdasarkan Menkes 2007.
Molecular characterization and new reports of two green algae from Bangladesh
Authors: Alfasane Md. Almujaddade , Chowdhury Md. Miraj Kobad , Mehnaz Maliha 
Published: June 2019

This communication portrays the molecular characterization and confirms the new reports of two fresh water green algae namely, Pithophora polymorpha Wittrock and Spirogyra maxima (Hassall) Wittrock from Bangladesh. The samples of these algal species were cultured and partial 18S rDNA was sequenced and analysed for their molecular identification. It was found that the primers reported here could sufficiently identify these algae as P. polymorpha and S. maxima. Furthermore, the Neighbour joining (NJ) tree generated from 18s rDNA sequences suggested that Spirogyra maxima of Bangladesh is distantly related to the cluster of S. juergensii and S. platensis. Pithophora polymorpha along with P. roettleri, P. sano and Pithophora sp. seems to form a strongly supported monophyletic group. The alga AP1 clusters with Pithophora and the alga AS1 clusters with Spirogyra. This study is the first-time report of molecular identification of Bangladeshi algae and a landmark towards the future exploration of thealgal biodiversity of Bangladesh.
Effect of arsenic exposure on human telomerase reverse transcriptase (hTERT) gene expression: Risk of cardiovascular diseases
Authors: Khaleda Laila , Forkan Mohammad Al , Wali Fahmida Binta , Alam Md Jibran , Datta Amit , Shawon Inzamamul Ismail , Hosain Nazmul , Rahman Md Zillur 
Published: June 2019

Background: Exposure to inorganic arsenic (iAs) through drinking water is currently a serious threat to public health of millions of people worldwide including Bangladesh. Some recent studies have shown that telomere dysfunction is emerging as an important factor in the pathogenesis of different cardiovascular diseases. Arsenic plays significant role on telomere dysfunction by altering the expression of telomere-related genes. The study was aimed to investigate the effects of arsenic on hTERT mRNA levels and their combined role in increasing CVD susceptibility.
Methods: In this cross sectional study, total of 50 CVD patients who underwent open heart surgery were recruited for this study. Urine, nail and cardiac tissue samples were collected and analyzed for As. Blood samples were quantified for hTERT expression analysis using real-time polymerase chain reaction.
Results: The hTERT mRNA expression was found approx. 10 fold higher in the As-exposed patients than the As-unexposed patients (p<0.01). A strong positive correlation (p<0.01, R>0.3) was found between the hTERT mRNA levels and As contents in the cardiac tissue, nail and urine samples of the study subjects. The significant increase (approx. 4 fold) in the hTERT mRNA expression was found in the patients with coronary artery disease (CAD) than the non-CAD patients.
Conclusions: The results of the study suggest that arsenic exposure increases hTERT mRNA expression which may in turn modify As-induced cardiovascular outcomes. The findings of this study will help to look deep into the association of As exposure in cardiovascular disease pathogenesis to open a new window in the diagnosis and treatment procedure of CVD.
Bangladesh Med Res Counc Bull 2019; 45: 03-10
Comparison of shear bond strength of orthodontic bracket bonding to teeth using light-curing units between halogen and LED: An in vitro study
Authors: Abdullah Md Kamal , Rafique Tanzila , Biswas Ashis Kumar , Ghosh Ranjit , Gafur Md Abdul , Hassan Gazi Shamim 
Published: June 2019

Background: Light-cured bonding systems have been widely accepted among orthodontists. Various light curing units are available now. Recently, the light emitting diode (LED) has been introduced alongside halogen light curing units. There is lack of information on the advantages and disadvantages of different light curing systems. The aim of this in vitro study was to compare the shear bond strength of orthodontic brackets and adhesive remnant index (ARI) of an adhesive cured with two different orthodontic light sources i.e. LED and halogen.
Methods: Forty four (22 in each group) extracted human premolars without any defects were etched with 37% phosphoric acid and cleansed with water spray and air dried. The sealant (Ortho Solo) was applied on the tooth surface and the brackets were bonded using adhesive (Enlight). Adhesives were cured with Halogen (Litex) and LED (D-LUX) for 40 seconds. Then the specimens were debonded later using a universal testing machine, with crosshead speed of 0.2 mm/min until the brackets were detached. Adhesive remnant index (ARI) scores were assessed under stereomicroscope at ×10 magnification.
Results: The shear bond strength in Halogen group was 19.73 ± 3.44 MPa and in the LED group 20.81±3.02 MPa which is little higher than halogen group. The proportion of being adhesive remaining index for ARI Score 1 in Halogen group was 5 (22.7%) and in LED group 7 (31.8%). While ARI Score 2 in the Halogen group was 13 (59.1%) compared to LED group 8 (36.4%). However, ARI Score 3 in Halogen group was 4 (18.2%) and in LED group 7 (31.8%). The overall model showing no significant difference.
Conclusion: Within limitations, this in vitro study showed the shear bond strength of orthodontic adhesives cured with a LED was statistically equivalent to those cured with a halogen light curing unit. There were significant differences in the ARI scores of the light-curing units tested. LED light-curing units can be suggested for the polymerization of orthodontic bonding adhesives because it showed a balanced effect on ARI index.
Bangladesh Med Res Counc Bull 2019; 45: 17-22
Comparative assessment of manual, rotary and reciprocating instruments for removal of root fillings, using stereomicroscope: An in vitro study
Authors: Ali Afzal , Hussain Sazid , Metgud Sandeep , Mishra Shashank , Sharma Ankita , Gupta Nikita 
Published: June 2019

Background: To investigate the efficiency of Hedstrom (H; Dentsply Maillefer) file, Protaper Universal Retreatment system (PTUR; Dentsply Maillefer), Mani NRT-GPR files (Mani, Japan) and WaveOne (WO; Dentsply Maillefer) Reciprocating files in removing Gutta Percha (GP) and sealer from root canals.
Methods: Sixty canals with less than 10° curvature from extracted human maxillary incisors were used. Root canal reinstrumentation was performed with H, PTUR, Mani NRT-GPR and WO files. Amount of residual root filling material (Gutta-percha and or sealer) were measured by using stereomicroscope. Data of GP or sealer remnants were statistically analyzed using one-way analysis of variance and Tukey test.
Results: There were no significant differences among 4 groups in terms of residual root filling material in the apical third (p > 0.05). H-file group showed highest amount of root residual root filling as compared to groups.
Conclusions: Reciprocating file system proved to be more efficient in removing the root canal fillings material than other retreatment file systems. H file group showed highest amount of root canal filling material.
Bangladesh Med Res Counc Bull 2019; 45: 54-61
New Oral Anticoagulants: An Update
Authors: Ahmad Quamruddin , Reza Md Mahin , Habib Md Ahosan , Masud Syed Faravee , Nasiruddin - , Khan Md Ahsanuzzaman , Ambiya Ahmed Shahed e , Ahmad Sonia Nasreen 
Published: June 2019

One of the most common and useful forms of medical intervention is anticoagulant therapy and it is the mainstay of treatment and prevention of thrombosis in different clinical settings, like atrial fibrillation (AF), acute coronary syndrome (ACS), acute venous thromboembolism (VTE), and in patients undergoing invasive cardiac procedures. More than 6 million patients in the United States receive long-term anticoagulation therapy for the prevention of thromboembolism due to AF, placement of a mechanical heart-valve prosthesis, or VTE.1 For more than 60 years, until 2009, warfarin and other vitamin K antagonists were the only class of oral anticoagulants (OAC) available. Although these drugs are highly effective in prevention of TE, their use is limited by a narrow therapeutic index that necessitates frequent monitoring and dose adjustments. This results in substantial risk and inconvenience, leading to inadequate anticoagulant prophylaxis. Recently some new OAC have been marketed which are effective, easier to use and has less side effects. Dabigatran is a new oral thrombin inhibitor and Rivaroxaban, Apixaban and Edoxaban are oral factor Xa inhibitors. This review outlines why these new OACs were essential and describes in detail about these new drugs.
J Bangladesh Coll Phys Surg 2019; 37(3): 135-150
Intracerebral Haemorrhage with Choriocarcinoma in a Teenager - A Case Report
Authors: Das Sukriti , Islam Md Manirul , Rashid Md Mamunur , Howlader Md Reaz Ahmed , Dey Sharbori , Mahbub Hasan 
Published: June 2019

Intracerebral haemorrhage is one of the uncommon initial CNS manifestations of choriocarcinoma in reproductive age group women. Disease is usually diagnosed by history, clinical examinations and investigations like CT scan of brain and chest, MRI of brain, USG, X-ray chest P/A view and high level of â-hCG in serum and CSF. Overall prognosis of this disease is generally good (80-90% long term survival with chemotherapy and radiotherapy). But intracranial metastasis has poor prognosis which comprises 3-28% of choriocarcinoma. Most intracranial metastasis occurs late in the course of disease but 20% experiences as first sign. Our patient is a teenager girl presented with convulsion and loss of consciousness. CT scan of brain revealed hemorrhage in right fronto-parietal region with ventricular extension, X-ray chest P/A view shows metastasis in mid zone of right lung, USG shows invasion in posterior myometrium and high concentration of serum â-hCG (273400 mUI/ ml) confirmed our diagnosis. This case report describes that the conservative treatment with radiotherapy and chemotherapy gives good outcome of with metastasic intracerebral haemorrhage with choriocarcinoma is rewarding with farther radio and chemotherapy.
J Bangladesh Coll Phys Surg 2019; 37(3): 151-155
Recurrent Abdominal Pain in Peutz-Jeghers Syndrome: A Case Report
Authors: Anwar Sayeeda , Kamal Nusrat , Khanom Rokeya , Roy Subrota Kumar , Kabir Farzana , Saha Ramkrishna 
Published: June 2019

Peutz-Jeghars Syndrome (PJS), also known as peri-orificial lentiginosis, is a condition of autosomal dominant inheritance. Here, mutation localized at (19p13.3) LKB1/ STK11. It is characterized by presence of mucocutaneous pigmentation and gastrointestinal (GI) hamartomatous polyps. This case of PJS, is a 7 year old girl who came with recurrent vomiting and abdominal pain for 1 year and weight loss for 8 months. She had multiple black pigmentation over lips and buccal mucosa. Endoscopy revealed multiple polyps in stomach and duodenum. Besides supportive management, polyps were removed by surgical intervention. Biopsy of these polyps showed hamartomatous type. Post operative period was uneventful. She recovered well. So far there was no recurrence of pain. She is on regular follow up.
J Bangladesh Coll Phys Surg 2019; 37(3): 160-164
Liver abscesses ultrasonic semiotics and its significance for the surgery method choosing
Authors: Yareshko V. G. , Zhivitsa S. G. , Otarashvili K. N. , Novak V. V. , Krivoruchko I. V. 
Published: June 2019

Significant progress has now been made in diagnosing, treating, reducing complications and lethality at liver abscesses. This is due to the displacement from the arsenal of surgery of complex and traumatic abdominal or trans thoraces approach to abscesses, which themselves created the problem of the postoperative period, complicated the course of an already severe infectious pathology. Modern minimally invasive technologies have significant advantages, especially with regard to interventional sonography, that is, the combined properties of diagnosis and treatment.
Purpose of the study. To objectify the choice of the method of surgical intervention of liver abscesses on the basis of a new self-developed ultrasound semiotics of the stage of the formation of abscesses.
Materials and methods. A comprehensive examination of 62 patients with liver abscesses was based on the study of the clinical picture of the liver abscesses, a bacteriological study of the contents, CT scan, and especially ultrasound, on the basis of which the ultrasound semiotics of the stages of the formation of abscesses was developed and implemented.
Results and discussion. According to the possibilities of ultrasound diagnosis of abscesses of the liver from the first signs of local inflammation in the liver to the final stage of formation of the pyogenic capsule, we identified four stages of their development: 1 stage – local inflammatory changes of the parenchyma without its destruction; Stage 2 – destructive changes of parenchyma without signs of distinct boundaries; Stage 3 – clear boundaries of destructive changes with a non-expressed capsule; Stage 4 – clear formation of a capsule with complete destruction of tissues.
The proposed ultrasonic semiotics allows us to determine the method of operation. Thus, at stages 1 and 2, and in some cases in 3 stages, there is no alternative to puncture-drainage methods in residual postoperative cavities. At stages 3 and 4, there are more advantages in laparoscopic operations, in some cases laparotomic.
Conclusions. the proposed classification of ultrasonic semiotics stages of the formation of liver abscesses most pathogenetically corresponds to the morphological changes of the abscess zone and, most importantly, is adapted to the choice of the method of operation.
Surgical correction of the chronic liver purulent-septic lesions
Authors: Kotenko O. G. , Gusev A. V. , Popov O. O. , Grinenko A. V. , Grigoryan M. S. , Yuzvuk K. O. , Zhylenko A. I. 
Published: June 2019

Purpose of the study. The purpose of the study is to improve the results of surgical treatment of patients with purulent-septic lesion of the liver substantiating the indication for resection method use.
Material and methods. The work is based on a comparative analysis of the results of examination and treatment of 64 patients aged 10 to 81 years old, with chronic liver abscesses in the department of surgery and liver transplantation during the 1995–2016 periods.
According to the tasks of the study patients are divided into two groups. In 30 (46,8%) patients (the study group), various types of anatomical resection of the liver with a purulent lesion were performed without its dissection during the operation; in 34 (53,2%) patients (group of comparison) they performed the disclosure, sanation, drainage of purulent cavity. The majority of patients with chronic liver abscesses treated the abscess with a puncture or drainage method under the control of ultrasound in other medical institutions of Ukraine.
Results. The results of diagnosis and treatment of 64 patients for chronic liver abscesses from 1995 to 2016 are analyzed. In the study group, the patients performed anatomical resection of the liver, in the comparison group – standard surgical interventions – the disclosure and drainage of the abscess of the liver. The duration of antibiotic therapy after surgery in the comparison group is significantly higher than in the study group, respectively, 22 ± 3,4 and 5,75 ± 1,6 days; p < 0,001. Second-line antibacterial drugs after draining operations were used more often (p < 0,001) than after resection interventions, respectively, in 94,1 and 6,6% of cases. The duration of treatment of patients in the hospital after surgery in the study group was less than in the comparison group, according to 15,1 ± 0,7 and 27,3 ± 3,05 days; total 25,9 ± 1,4 and 45,7 ± 3,45 days (p < 0,001). After drainage operations, drainages from the abdominal cavity were removed later than after resection interventions, respectively, 17,1 ± 2,8 and 6,35 ± 1,1 days (p < 0,001), through.
Conclusion. Resection for chronic purulentseptic lesions of the liver is the priority methods of surgical treatment. The analysis of the obtained results allows us to conclude that resection technologies contribute to the rapid normalization of physical and social rehabilitation of patients with septic liver damage.
Healing of diabetic ulcers in conditions of biological stimulation of reparation
Authors: Petrushenko V. V. , Grebeniuk D. I. , Apasova N. V. , Mosondz V. V. 
Published: June 2019

Purpose of study. The repertory effect evaluation of autologous platelet-rich plasma in the treatment of patients with diabetic foot in stage 2.
Materials and methods. The study included 32 patients with diagnosisof diabetic foot in stage 2. At the time of inclusion in the study, all patients had a defect of the skin and subcutaneous fat on the foot, measuring 3–6 cm2, which was not corrected by traditional methods for 3–4 months. The comparison group consisted of 18 patients (56,25%) who received standard therapy. The study group consisted of 14 patients (43,75%), to whom standard therapy was supplemented by local serial administration of autologous platelet-rich plasma. To assess the effectiveness of the therapy, the area of the ulcerative defect was measured before manipulation, as well as at 1 week intervals until the ulcer was completely healed.
Results. Our experience with autologous platelet-rich plasma in the treatment of patients with diabetic foot in stage 2 demonstrated the effectiveness of this technique. A progressive, significant (p < 0,01) decrease in the area of the ulcerative defect starting from the 14th day was noted. When using platelet-rich plasma, we managed to achieve complete healing of diabetic ulcers in 64,2% of patients on day 35 and in 100% of patients on day 42.
Conclusion. Local administration of an autologous platelet-rich plasma allows the complete healing of diabetic ulcers in stage 2 with an area of 3–6 cm2 for 6 weeks.
Kur’an Meallerinin Muhatapları Tarafından Anlaşılabilirliğine ilişkin Bir Araştırma
Authors: GÜLPAK Emine 
Published: June 2019

Kur’an-ı Kerîm Arap yarımadası, Hicaz bölgesinde
nazil olmuştur. Kur’an’ın Arapça bir kitap olarak nazil olması, İlahi hitabın
ilk muhataplarının dilinin Arapça olmasının doğal sonucudur. İlk Müslümanların lisan bakımından Kur’an’ı anlama problemi
olmasa da İslam’ın farklı coğrafyalara yayılması ile Müslümanların Kutsal
kitaplarını anlayamama problemi nüksetmiş, böylelikle Kur’an-ı Kerîm’in tercüme
faaliyetleri başlamıştır. Kur’an anadili Arapça olmayan insanların ilahî mesajı
anlaması gayesiyle birçok dile olduğu gibi Türkçeye de tercüme edilmiştir. Bu çalışmanın amacı Türkçe Kur’an meallerinin
Türk okurları açısından anlaşılabilirliğini tespit etmektir. Bu amaçla çeşitli
meallerden sekiz ayet seçilmiş, bu ayetlerden ne anladıkları araştırmaya katılan
kişilere sorulmuştur. Araştırmanın örneklemi cinsiyet, yaş ve meslekleri farklı,
çeşitli eğitim düzeylerinde on beş kişiden oluşmaktadır. Araştırmada nitel veri
toplama yöntemlerinden görüşme yöntemi kullanılmış, veriler yarı
yapılandırılmış görüşme formuna bire bir not tutularak toplanmıştır.
Katılımcıların verdiği cevaplar genel olarak incelendiğinde meallerin Türk
okurları açısından yeterince anlaşılır olmadığı, yanlış anlaşılmaya sebebiyet
verecek nitelikte olduğu tespit edilmiştir.
PELATIHAN PEMBUATAN BONEKA JARI BERGAMBAR DALAM MENINGKATKAN KEMAMPUAN MEMBACA ANAK USIA DINI DI KECAMATAN V KOTO KAMPUNG DALAM KABUPATEN PADANG PARIAMAN
Authors: Rakimahwati Rakimahwati 
Published: June 2019

ABSTRAK

Tujuan dari pelatihan ini adalah untuk mengenalkan media pembelajaran pada guru yaitu (1) Menciptakan media pembelajaran membaca yang menyenangkan untuk anak; (2) Guru memiliki keterampilan dalam merancang boneka jari bergambar sebagai media pembelajaran membaca anak usia dini. Subjek pelatihan ini adalah anak Taman Kanak-kanak Melati Kecamatan V Koto Kampung Dalam Kabupaten Padang Pariaman. Sasaran dari pelatihan ini adalah guru-guru PAUD baik formal maupun nonformal se-Kecamatan V Koto Kampung Dalam Kabupaten Padang Pariaman. Adapun mitra dalam kegiatan ini adalah IGTKI Kecamatan V Koto Kampung Dalam Kabupaten Padang Pariaman. Pelaksanaan pelatihan adalah survei awal untuk mendata peserta pelatihan, mengurus surat izin untuk melaksanakan pelatihan, membuat buku panduan pelatihan, pelaksanaan pelatihan. Metode yang digunakan adalah praktek langsung. Metode praktek langsung digunakan agar peserta pelatihan mampu menciptakan boneka jari bergambar dalam meningkatkan kemampuan membaca anak. Hasil yang diperoleh guru dapat menciptakan boneka jari bergambar dengan empat tema untuk pengenalan membaca anak usia dini.

Kata Kunci: Anak Usia Dini, Boneka jari bergambar, Membaca

ABSTRACT
The purpose of this training is to introduce learning media to teachers (1) Creating a fun learning media for children; (2) The teacher has the skills in designing pictorial finger puppets as a medium for early childhood reading learning. The subjects of this training were children of TK Melati in V Koto Kampung Dalam Kabupaten Padang Pariaman. The target of this training is PAUD teachers both formal and non-formal in V Koto Kampung Dalam Kabupaten Padang Pariaman. The partners in this activity were IGTKI Kampung Dalam Kabupaten Padang Pariaman. The training is an initial survey to record trainees, manage permits to carry out training, create training manuals, conduct training. The method used is direct practice. Direct practice methods are used so that trainees are able to create illustrated finger puppets in improving children's reading skills.the result obtained by the teacher can create illustrated finger puppets with four themes for early chilhood reading.

Keyword: early childhood, picture finger puppets, ability to read
Utopias
Authors: Editorial Comissão 
Published: June 2019

As utopias têm a idade dos sonhos humanos de felicidade e plena emancipação. As utopias não são um privilégio ou atributo de uma única época, de um único povo. As utopias são a permanente chama que nos leva, mesmo nas circunstâncias mais difíceis, e sobretudo nelas, a acreditar que a vida, individual e coletiva, pode ser melhor, ser promessa de felicidade. [CONTINUA...]