bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protection for natural gas exports to develop Argentina’s unconventional resources potential
Authors: Macías Francisco A , Artagaveytia Pablo A , Santamaría Gonzalo 
Published: September 2019

Abstract
This article intends to outline the main features of a new export promotion regime that Argentina needs to allow the development of its natural gas unconventional resources through long-term export agreements. It describes the current scenario of Argentina’s gas market and the challenges that gas exports from Argentina have faced in recent years, while proposing possible improvements to the current legal regime to generate the conditions required to enable the development of new regional and international markets for its world-class unconventional resources.
Evaluation of antifibrotic and antifungal combined therapies in experimental pulmonary paracoccidioidomycosis
Authors: Finato Angela C , Almeida Débora F , dos Santos Amanda R , Nascimento Dejair C , Cavalcante Ricardo S , Mendes Rinaldo P , Soares Cléverson T , Paniago Anamaria M M , Venturini James 
Published: September 2019

AbstractParacoccidioidomycosis (PCM) is a systemic mycosis caused by the Paracoccidioides genus. Most of the patients with chronic form present sequelae, like pulmonary fibrosis, with no effective treatment, leading to impaired lung functions. In the present study, we aimed to investigate the antifibrotic activity of three compounds: pentoxifylline (PTX), azithromycin (AZT), and thalidomide (Thal) in a murine model of pulmonary PCM treated with itraconazole (ITC) or cotrimoxazole (CMX). BALB/c mice were inoculated with P. brasiliensis (Pb) by the intratracheal route and after 8 weeks, they were submitted to one of the following six treatments: PTX/ITC, PTX/CMX, AZT/ITC, AZT/CMX, Thal/ITC, and Thal/CMX. After 8 weeks of treatment, the lungs were collected for determination of fungal burden, production of OH-proline, deposition of reticulin fibers, and pulmonary concentrations of cytokines and growth factors. Pb-infected mice treated with PTX/ITC presented a reduction in the pulmonary concentrations of OH-proline, associated with lower concentrations of interleukin (IL)-6, IL-17, and transforming growth factor (TGF)-β1 and higher concentrations of IL-10 compared to the controls. The Pb-infected mice treated with AZT/CMX exhibited decreased pulmonary concentrations of OH-proline associated with lower levels of TGF-β1, and higher levels of IL-10 compared controls. The mice treated with ITC/Thal and CMX/Thal showed intense weight loss, increased deposition of reticulin fibers, high pulmonary concentrations of CCL3, IFN-γ and VEGF, and decreased concentrations of IL-6, IL-1β, IL-17, and TGF-β1. In conclusion, our findings reinforce the antifibrotic role of PTX only when associated with ITC, and AZT only when associated with CMX, but Thal did not show any action upon addition.
TOI-150b and TOI-163b: two transiting hot Jupiters, one eccentric and one inflated, revealed by TESS near and at the edge of the JWST CVZ
Authors: Kossakowski Diana , Espinoza Néstor , Brahm Rafael , Jordán Andrés , Henning Thomas , Rojas Felipe , Kürster Martin , Sarkis Paula , Schlecker Martin , Pozuelos Francisco J , Barkaoui Khalid , Jehin Emmanuël , Gillon Michaël , Matthews Elisabeth , Horch Elliott P , Ciardi David R , Crossfield Ian J M , Gonzales Erica , Howell Steve B , Matson Rachel , Schlieder Joshua , Jenkins Jon , Ricker George , Seager Sara , Winn Joshua N , Li Jie , Rose Mark E , Smith Jeffrey C , Dynes Scott , Morgan Ed , Villasenor Jesus Noel , Charbonneau David , Jaffe Tess , Yu Liang , Bakos Gaspar , Bhatti Waqas , Bouchy François , Collins Karen A , Collins Kevin I , Csubry Zoltan , Evans Phil , Jensen Eric L N , Lovis Christophe , Marmier Maxime , Nielsen Louise D , Osip David , Pepe Francesco , Relles Howard M , Ségransan Damien , Shporer Avi , Stockdale Chris , Suc Vincent , Turner Oliver , Udry Stéphane 
Published: September 2019

Abstract
We present the discovery of TYC9191-519-1b (TOI-150b, TIC 271893367) and HD271181b (TOI-163b, TIC 179317684), two hot Jupiters initially detected using 30-min cadence Transiting Exoplanet Survey Satellite (TESS) photometry from Sector 1 and thoroughly characterized through follow-up photometry (CHAT, Hazelwood, LCO/CTIO, El Sauce, TRAPPIST-S), high-resolution spectroscopy (FEROS, CORALIE), and speckle imaging (Gemini/DSSI), confirming the planetary nature of the two signals. A simultaneous joint fit of photometry and radial velocity using a new fitting package juliet reveals that TOI-150b is a $1.254\pm 0.016\ \rm {R}_ \rm{J}$, massive ($2.61^{+0.19}_{-0.12}\ \rm {M}_ \rm{J}$) hot Jupiter in a 5.857-d orbit, while TOI-163b is an inflated ($R_ \rm{P}$ = $1.478^{+0.022}_{-0.029} \,\mathrm{ R}_ \rm{J}$, $M_ \rm{P}$ = $1.219\pm 0.11 \, \rm{M}_ \rm{J}$) hot Jupiter on a P = 4.231-d orbit; both planets orbit F-type stars. A particularly interesting result is that TOI-150b shows an eccentric orbit ($e=0.262^{+0.045}_{-0.037}$), which is quite uncommon among hot Jupiters. We estimate that this is consistent, however, with the circularization time-scale, which is slightly larger than the age of the system. These two hot Jupiters are both prime candidates for further characterization – in particular, both are excellent candidates for determining spin-orbit alignments via the Rossiter–McLaughlin (RM) effect and for characterizing atmospheric thermal structures using secondary eclipse observations considering they are both located closely to the James Webb Space Telescope (JWST) Continuous Viewing Zone (CVZ).
Group connectivity in COSMOS: a tracer of mass assembly history
Authors: Darragh Ford E , Laigle C , Gozaliasl G , Pichon C , Devriendt J , Slyz A , Arnouts S , Dubois Y , Finoguenov A , Griffiths R , Kraljic K , Pan H , Peirani S , Sarron F 
Published: September 2019

ABSTRACT
Cosmic filaments are the channel through which galaxy groups assemble their mass. Cosmic connectivity, namely the number of filaments connected to a given group, is therefore expected to be an important ingredient in shaping group properties. The local connectivity is measured in COSMOS around X-ray-detected groups between redshift 0.5 and 1.2. To this end, large-scale filaments are extracted using the accurate photometric redshifts of the COSMOS2015 catalogue in two-dimensional slices of thickness 120 comoving Mpc centred on the group’s redshift. The link between connectivity, group mass, and the properties of the brightest group galaxy (BGG) is investigated. The same measurement is carried out on mocks extracted from the light-cone of the hydrodynamical simulation Horizon-AGN in order to control systematics. More massive groups are on average more connected. At fixed group mass in low-mass groups, BGG mass is slightly enhanced at high connectivity, while in high-mass groups BGG mass is lower at higher connectivity. Groups with a star-forming BGG have on average a lower connectivity at given mass. From the analysis of the Horizon-AGN simulation, we postulate that different connectivities trace different paths of group mass assembly: at high group mass, groups with higher connectivity are more likely to have grown through a recent major merger, which might be in turn the reason for the quenching of the BGG. Future large-field photometric surveys, such as Euclid and LSST, will be able to confirm and extend these results by probing a wider mass range and a larger variety of environment.
Limits on a population of collisional-triples as progenitors of Type-Ia supernovae
Authors: Hallakoun Na’ama , Maoz Dan 
Published: September 2019

ABSTRACT
The progenitor systems of Type-Ia supernovae (SNe Ia) are yet unknown. The collisional-triple SN Ia progenitor model posits that SNe Ia result from head-on collisions of binary white dwarfs (WDs), driven by dynamical perturbations by the tertiary stars in mild-hierarchical triple systems. To reproduce the Galactic SN Ia rate, at least ∼30–55 per cent of all WDs would need to be in triple systems of a specific architecture. We test this scenario by searching the Gaia DR2 data base for the postulated progenitor triples. Within a volume out to 120 pc, we search around Gaia-resolved double WDs with projected separations up to 300 au, for physical tertiary companions at projected separations out to 9000 au. At 120 pc, Gaia can detect faint low-mass tertiaries down to the bottom of the main sequence and to the coolest WDs. Around 27 double WDs, we identify zero tertiaries at such separations, setting a 95 per cent confidence upper limit of 11 per cent on the fraction of binary WDs that are part of mild hierarchical triples of the kind required by the model. As only a fraction (likely ∼10 per cent) of all WDs are in <300 au WD binaries, the potential collisional-triple progenitor population appears to be at least an order of magnitude (and likely several) smaller than required by the model.
Heterogeneity of inverted calcium ii H:K ratio cluster galaxies
Authors: Pimbblet K A , Crossett J P , Fraser-McKelvie A 
Published: September 2019

ABSTRACT
The ratio of calcium ii H plus Hϵ to calcium ii K inverts as a galaxy stellar population moves from being dominated by older stars to possessing more A and B class stars. This ratio – the H:K ratio – can serve as an indicator of stellar populations younger than 200 Myr. In this work, we provide a new method to determine H:K, and apply it to spectra taken of cluster galaxies in Abell 3888. Although H:K is on average systematically lower for the cluster than for a wider field sample, we show that H:K does not have a simple relationship with other indices such as the equivalent widths of Hδ and [O ii] beyond having a high value for strong [O ii] emission. Moreover, strongly inverted galaxies with H:K &gt; 1.1 have no preferred location within the cluster and are only slightly lower in their velocity dispersions around the cluster compared to strongly emitting [O ii] galaxies. Our results indicate that selecting galaxies on H:K inversion results in a heterogeneous sample formed via a mixture of pathways that likely includes, but may not be limited to, merging spiral galaxies, and quiescent galaxies accreting lower mass, gas-rich companions. In concert with other selection criteria, H:K can provide a means to select a more ‘pure’ passive sample or to aid in the selection of highly star-forming galaxies, especially where other spectral line indicators such as H α may not have been observed.
The magnetic early B-type stars – III. A main-sequence magnetic, rotational, and magnetospheric biography
Authors: Shultz M E , Wade G A , Rivinius Th , Alecian E , Neiner C , Petit V , Owocki S , ud-Doula A , Kochukhov O , Bohlender D , Keszthelyi Z ,   the MiMeS and BinaMIcS Collaborations
Published: September 2019

ABSTRACT
Magnetic confinement of stellar winds leads to the formation of magnetospheres, which can be sculpted into centrifugal magnetospheres (CMs) by rotational support of the corotating plasma. The conditions required for the CMs of magnetic early B-type stars to yield detectable emission in H α – the principal diagnostic of these structures – are poorly constrained. A key reason is that no detailed study of the magnetic and rotational evolution of this population has yet been performed. Using newly determined rotational periods, modern magnetic measurements, and atmospheric parameters determined via spectroscopic modelling, we have derived fundamental parameters, dipolar oblique rotator models, and magnetospheric parameters for 56 early B-type stars. Comparison to magnetic A- and O-type stars shows that the range of surface magnetic field strength is essentially constant with stellar mass, but that the unsigned surface magnetic flux increases with mass. Both the surface magnetic dipole strength and the total magnetic flux decrease with stellar age, with the rate of flux decay apparently increasing with stellar mass. We find tentative evidence that multipolar magnetic fields may decay more rapidly than dipoles. Rotational periods increase with stellar age, as expected for a magnetic braking scenario. Without exception, all stars with H α emission originating in a CM are (1) rapid rotators, (2) strongly magnetic, and (3) young, with the latter property consistent with the observation that magnetic fields and rotation both decrease over time.
X-ray spectral analysis of the neutron star in SNR 1E 0102.2−7219
Authors: Hebbar Pavan R , Heinke Craig O , Ho Wynn C G 
Published: September 2019

ABSTRACT
We re-analysed numerous archival Chandra X-ray observations of the bright supernova remnant (SNR) 1E 0102.2−7219 in the Small Magellanic Cloud, to validate the detection of a neutron star (NS) in the SNR by Vogt et al. Careful attention to the background is necessary in this spectral analysis. We find that a blackbody + power-law model is a decent fit, suggestive of a relatively strong B field and synchrotron radiation, as in a normal young pulsar, though the thermal luminosity would be unusually high for young pulsars. Among realistic NS atmosphere models, a carbon atmosphere with B = 1012  G best fits the observed X-ray spectra. Comparing its unusually high thermal luminosity ($L_{\mathrm{ bol}} = 1.1_{-0.5}^{+1.6}\times 10^{34}$ erg s−1) to other NSs, we find that its luminosity can be explained by decay of an initially strong magnetic field (as in magnetars or high B-field pulsars) or by slower cooling after the supernova explosion. The nature of the NS in this SNR (and of others in the Magellanic Clouds) could be nicely confirmed by an X-ray telescope with angular resolution like Chandra, but superior spectral resolution and effective area, such as the Lynx concept.
Next-generation forward genetic screens: using simulated data to improve the design of mapping-by-sequencing experiments in Arabidopsis
Authors: Wilson-Sánchez David , Lup Samuel Daniel , Sarmiento-Mañús Raquel , Ponce María Rosa , Micol José Luis 
Published: September 2019

AbstractForward genetic screens have successfully identified many genes and continue to be powerful tools for dissecting biological processes in Arabidopsis and other model species. Next-generation sequencing technologies have revolutionized the time-consuming process of identifying the mutations that cause a phenotype of interest. However, due to the cost of such mapping-by-sequencing experiments, special attention should be paid to experimental design and technical decisions so that the read data allows to map the desired mutation. Here, we simulated different mapping-by-sequencing scenarios. We first evaluated which short-read technology was best suited for analyzing gene-rich genomic regions in Arabidopsis and determined the minimum sequencing depth required to confidently call single nucleotide variants. We also designed ways to discriminate mutagenesis-induced mutations from background Single Nucleotide Polymorphisms in mutants isolated in Arabidopsis non-reference lines. In addition, we simulated bulked segregant mapping populations for identifying point mutations and monitored how the size of the mapping population and the sequencing depth affect mapping precision. Finally, we provide the computational basis of a protocol that we already used to map T-DNA insertions with paired-end Illumina-like reads, using very low sequencing depths and pooling several mutants together; this approach can also be used with single-end reads as well as to map any other insertional mutagen. All these simulations proved useful for designing experiments that allowed us to map several mutations in Arabidopsis.
Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification
Authors: Hoffman Gabriel E , Bendl Jaroslav , Girdhar Kiran , Schadt Eric E , Roussos Panos 
Published: September 2019

Abstract
Identifying functional variants underlying disease risk and adoption of personalized medicine are currently limited by the challenge of interpreting the functional consequences of genetic variants. Predicting the functional effects of disease-associated protein-coding variants is increasingly routine. Yet, the vast majority of risk variants are non-coding, and predicting the functional consequence and prioritizing variants for functional validation remains a major challenge. Here, we develop a deep learning model to accurately predict locus-specific signals from four epigenetic assays using only DNA sequence as input. Given the predicted epigenetic signal from DNA sequence for the reference and alternative alleles at a given locus, we generate a score of the predicted epigenetic consequences for 438 million variants observed in previous sequencing projects. These impact scores are assay-specific, are predictive of allele-specific transcription factor binding and are enriched for variants associated with gene expression and disease risk. Nucleotide-level functional consequence scores for non-coding variants can refine the mechanism of known functional variants, identify novel risk variants and prioritize downstream experiments.
Attending to Eliza: rapid brain responses reflect competence attribution in virtual social feedback processing
Authors: Schindler Sebastian , Miller Gregory A , Kissler Johanna 
Published: September 2019

Abstract
In the age of virtual communication, the source of a message is often inferred rather than perceived, raising the question of how sender attributions affect content processing. We investigated this issue in an evaluative feedback scenario. Participants were told that an expert psychotherapist, a layperson or a randomly acting computer was going to give them online positive, neutral or negative personality feedback while high-density EEG was recorded. Sender attribution affected processing rapidly, even though the feedback was on average identical. Event-related potentials revealed a linear increase with attributed expertise beginning 150 ms after disclosure and most pronounced for N1, P2 and early posterior negativity components. P3 and late positive potential amplitudes were increased for both human senders and for emotionally significant (positive or negative) feedback. Strikingly, feedback from a putative expert prompted large P3 responses, even for inherently neutral content. Source analysis localized early enhancements due to attributed sender expertise in frontal and somatosensory regions and later responses in the posterior cingulate and extended visual and parietal areas, supporting involvement of mentalizing, embodied processing and socially motivated attention. These findings reveal how attributed sender expertise rapidly alters feedback processing in virtual interaction and have implications for virtual therapy and online communication.
Are “statutory executors” personally liable for payment of U.S. Federal estate tax?
Authors: Berry Dean C 
Published: September 2019

Abstract
What are the U.S. tax obligations of a financial institution—such as a bank—which holds, at the death of an account holder, assets that are subject to U.S. Federal estate tax? If the bank fails to comply with these obligations, may it become personally liable to the U.S. Government if the tax is not fully paid?
Short-column acetabular fracture fixation through a mini-pararectus approach in anteriorly displaced acetabular fractures: A case series
Authors: Badran Mahmoud , Farouk Osama , Kamal Ayman , Abubeih Hossam , Khaled Mohamed 
Published: September 2019

Background:
A mini-pararectus approach has been described as a minimally invasive approach for stabilizing acetabular fractures. This approach allows a direct view of anteriorly displaced acetabular fractures. In this preliminary study, we report the outcomes of short-column plating, using either a pelvic-brim plate or a spring plate to stabilize anteriorly and medially displaced fractures.

Methods:
Nine patients were included in this report, which was conducted between June 2015 and October 2016 in Assiut University Hospital, which is a level 1 trauma center in Upper Egypt. Eight patients had a transverse fracture of the acetabulum, and a single patient had a posterior hemi-transverse fracture of the anterior column. After the mini-pararectus approach through which anatomical reduction of the fracture was achieved, short-column plating, either a pelvic-brim plate or spring plate was introduced through this 3-5 cm incision. Outcomes were assessed.

Results:
The mean operative time was 88.8 min (range, 60-120 min). The mean blood loss was 78.8 mL (range, 50-150 mL). The maximal fracture displacement mean was 7 mm (range, 4–18 mm) preoperatively. According to the Radiologic Matta score, anatomical reduction of the fracture (0–1 mm displacement) was achieved in all patients. No complications of metal failure or secondary fracture displacement were encountered.

Conclusions:
Short-column plating through a mini-pararectus approach can be an alternative option for stabilizing acetabular fractures in a minimally invasive way in selected patients.

Level of Evidence:
Level IV.
Longitudinal Relationship Between Time-Out and Child Emotional and Behavioral Functioning
Authors: Knight Rachel M. , Albright Jeremy , Deling Lindsay , Dore-Stites Dawn , Drayton Amy K. 
Published: September 2019

ABSTRACT:

Objective:
Time-out is a widely used child discipline strategy and one of the only strategies currently recommended by the American Academy of Pediatrics. Despite its widespread use and significant evidence to support its effectiveness in decreasing problem behavior, time-out is often suggested to be harmful or ineffective by the popular media and select professional organizations. Empirical evidence regarding possible side effects of time-out is limited. The present study examined the relationship between reported use of time-out and child emotional and behavioral functioning and parent-child relationships using longitudinal, archival data.

Methods:
The study used archival, longitudinal data from the Early Head Start Research and Evaluation study. This study tracked families with children in Early Head Start at 3 different time points as follows: baseline (aged 0–3 years), pre-kindergarten, and fifth grade. Parent interviews, including questions on the use of time-out, were conducted when the children were 36 months old. Indicators of child emotional and behavioral health were measured at 36 months, pre-K, and fifth grade. Statistical analyses were completed to assess for potential side effects of time-out on child behavioral and emotional functioning and parent-child relationships.

Results:
Analyses for all outcome variables suggest no significant difference for children whose parents reported using time-out versus those who did not.

Conclusion:
Parental reported use of time-out was not associated with long-term negative outcomes. Further research in this area is necessary to continue to address the multitude of concerns related to time-out that are presented by the media.