bluuebunny/crossref_metadata_2025_split huggingface dataset:
Slaves for Pleasure in Arabic Sex and Slave Purchase Manuals from the Tenth to the Twelfth Centuries
Authors: Myrne Pernilla 
Published: June 2019

Abstract
Women probably made up the majority of the slave population in the medieval Islamic world, most of them used for domestic service. As men were legally permitted to have sexual relations with their female slaves, enslaved women could be used for sexual service. Erotic compendia and sex manuals were popular literature in the premodern Islamic world, and are potentially rich sources for the history of sex slavery, especially when juxtaposed with legal writings. This article uses Arabic sex manuals and slave purchase manuals from the tenth to the twelfth century to investigate the attitudes toward sexual slavery during this period, as well as the changing ethnicities and origins of slaves, and the use of legal manipulations.
A Feed Forward Neural Network Based on Model Output Statistics for Short-Term Hurricane Intensity Prediction
Authors: Cloud Kirkwood A. , Reich Brian J. , Rozoff Christopher M. , Alessandrini Stefano , Lewis William E. , Delle Monache Luca 
Published: June 2019

Abstract
A feed forward neural network (FFNN) is developed for tropical cyclone (TC) intensity prediction, where intensity is defined as the maximum 1-min average 10-m wind speed. This deep learning model incorporates a real-time operational estimate of the current intensity and predictors derived from Hurricane Weather Research and Forecasting (HWRF; 2017 version) Model forecasts. The FFNN model is developed with the operational constraint of being restricted to 6-h-old HWRF data. Best track intensity data are used for observational verification. The forecast training data are from 2014 to 2016 HWRF reforecast data and cover a wide variety of TCs from both the Atlantic and eastern Pacific Ocean basins. Cross validation shows that the FFNN increasingly outperforms the operational observation-adjusted HWRF (HWFI) in terms of mean absolute error (MAE) at forecast lead times from 3 to 57 h. Out-of-sample testing on real-time data from 2017 shows the HWFI produces lower MAE than the FFNN at lead times of 24 h or less and similar MAEs at later lead times. On the other hand, the 2017 data indicate significant potential for the FFNN in the prediction of rapid intensification (RI), with RI defined here as an intensification of at least 30 kt (1 kt ≈ 0.51 m s−1) in a 24-h period. The FFNN produces 4 times the number of hits in HWFI for RI. While the FFNN has more false alarms than the HWFI, Brier skill scores show that, in the Atlantic, the FFNN has significantly greater skill than the HWFI and probabilistic Statistical Hurricane Intensity Prediction System RI index.
Does training in a top-down approach influence recorded goals and treatment plans?
Authors: Jutzi Katelyn S. R. , Linkewich Elizabeth , Hunt Anne W. , McEwen Sara 
Published: June 2019

Background. Five stroke rehabilitation teams were supported in the implementation of Cognitive Orientation to daily Occupational Performance (CO-OP) as part of a knowledge translation (KT) project called CO-OP KT. Medical record auditors noted there was occasionally a disconnect between client goals and treatment plans, revealing a need to better understand the characteristics of each and their relationship to each other. Purpose. This study aimed to examine the characteristics of goals and treatment plans in occupational therapy before and after CO-OP KT. Method. A descriptive secondary analysis of medical record data was employed. Findings. Post intervention, there was a change in goal specificity ( p = .04) and therapist–client goal alignment ( p = .05). Occupation-based goals were often paired with a bottom-up, impairment-based treatment. Top-down treatments, when present, lacked the same detail given to bottom-up plans. Implications. CO-OP KT seemed to lead to more specific goals, but matching top-down treatment plans were not found.
How many older adults receive drugs of questionable clinical benefit near the end of life? A cohort study
Authors: Morin Lucas , Wastesson Jonas W , Laroche Marie-Laure , Fastbom Johan , Johnell Kristina 
Published: June 2019

Background: The high burden of disease-oriented drugs among older adults with limited life expectancy raises important questions about the potential futility of care. Aim: To describe the use of drugs of questionable clinical benefit during the last 3 months of life of older adults who died from life-limiting conditions. Design: Longitudinal, retrospective cohort study of decedents. Death certificate data were linked to administrative and healthcare registries with national coverage in Sweden. Setting: Older adults (≥75 years) who died from conditions potentially amenable to palliative care between 1 January and 31 December 2015 in Sweden. We identified drugs of questionable clinical benefit from a set of consensus-based criteria. Results: A total of 58,415 decedents were included (mean age, 87.0 years). During their last 3 months of life, they received on average 8.9 different drugs. Overall, 32.0% of older adults continued and 14.0% initiated at least one drug of questionable clinical benefit (e.g. statins, calcium supplements, vitamin D, bisphosphonates, antidementia drugs). These proportions were highest among younger individuals (i.e. aged 75–84 years), among people who died from organ failure and among those with a large number of coexisting chronic conditions. Excluding people who died from acute and potentially unpredictable fatal events had little influence on the results. Conclusion: A substantial share of older persons with life-limiting diseases receive drugs of questionable clinical benefit during their last months of life. Adequate training, guidance and resources are needed to rationalize and deprescribe drug treatments for older adults near the end of life.
Cost-effectiveness of a peer mentoring intervention to improve disease self-management practices and self-efficacy among African American women with systemic lupus erythematosus: analysis of the Peer Approaches to Lupus Self-management (PALS) pilot study
Authors: Williams E M , Dismuke C L , Faith T D , Smalls B L , Brown E , Oates J C , Egede L E 
Published: June 2019

Objective The Peer Approaches to Lupus Self-management (PALS) program was developed as a peer mentoring tool to improve health behaviors, beliefs, and outcomes in African American women with systemic lupus erythematosus (SLE). This study aims to assess the cost of the PALS intervention and determine its effectiveness when compared to existing treatments. Methods Peer mentors and mentees were paired on shared criteria such as life stage, marital status, or whether they were mothers. This 12-week program consisted of a weekly peer mentoring session by telephone. Cost of healthcare utilization was evaluated by assessing the healthcare costs pre- and post-intervention. Validated measures of quality of life, self-management, disease activity, depression, and anxiety were collected. Total direct program costs per participant were totaled and used to determine average per unit improvement in outcome measures. The benefit-cost ratio and pre- versus post-intervention hospital charges were examined. Results A total of 20 mentees and 7 mentors were enrolled in the PALS program. All PALS pairs completed 12 sessions lasting an average of 54 minutes. Mentees reported statistically significant decreases in patient-reported disease activity, depression, and anxiety, with improved trends in patient activation or patient engagement in their disease and management. The total cost per patient was $1291.50, which was $107.62 per patient per week. There was a savings of $23,417 per individual receiving the intervention with a benefit-cost ratio of 18.13 per patient. Conclusion These findings suggest that the PALS intervention was effective in improving patient-level factors and was cost-effective. Future research will need to validate these findings in a larger sample.
Experimental and numerical determination of mode II fracture toughness of woven composites verified through unidirectional composite test data
Authors: Healey Rowan , Chowdhury Nabil M , Chiu Wing Kong , Wang John 
Published: June 2019

Due to the increase in prevalence of fibre-reinforced polymer matrix composites (FRPMC) in aircraft structures, the need for adaption of failure prediction tools such as fatigue spectra has become more pertinent. Fracture toughness is an important measure with regard to fatigue, while adequate techniques and an ASTM standard for unidirectional FRPMC exist, there are mixed opinions when investigating woven FRPMC. This study describes a three-dimensional finite element model developed to assist in determining the mode II interlaminar fracture toughness ( G IIc) of fibre-reinforced woven composites, validated by an experimental and numerical comparison of G IIc determination for unidirectional FRPMC. Experimental testing mirroring the ASTM D7905 resulted in a measure of 1176 J m−2 for the unidirectional specimen, while comparisons made with the literature achieved an average value of 1459.24 J m−2 or the woven specimen. Three numerical methods were employed due to their prominence in the literature: displacement field, virtual crack closure techniques and the J integral. Both the J integral and the displacement field three-dimensional models produced satisfactory unidirectional G IIc estimates of 1284 and 1116.8 J m−2, respectively. Displacement field had a 5% uncertainty in G IIc when compared with experimental results, while J integral had an approximately 8.5% uncertainty. Extending the analysis to the woven specimens, values of 1302.8 and 1465.3 J m−2 were obtained from J integral and displacement field methods, respectively, both within 10% of the experimental values. Hence, numerically determined unidirectional G IIc values were verified with experimental results, leading to the successful employment and extension to woven composites which displayed similar agreement.
A New Era for Rotational Atherectomy: An Australian Perspective
Authors: Bamford Paul , Parkinson Michael David , Gunalingam Brendan , David Michael , Lau George Tat-Ming 
Published: June 2019

Background: Rotational atherectomy (RA) has been used in percutaneous coronary intervention (PCI) for 30 years. With advances in technology, this observational study looks at how rates of RA have changed over the past decade in Australia in relation to PCI and coronary artery bypass graft (CABG) rates. Methods: Retrospective analysis of RA, PCI, and CABG rates per Australian state from Australian Government Department of Human Services’ data on Medicare items from 2007 to 2017 was carried out. Results: There were 149 RA procedures in 2007, increasing to 452 in 2017. Rotational atherectomy accounted for 0.67% of PCI procedures in 2007, increasing to 1.48% in 2018 (+0.81%, 95% confidence interval [CI] = [0.64%-0.91%]; P < .001). Most of this increase has come from procedures in New South Wales (441% increase). Australian PCI rate increased from 22 301 to 30 480. Rate of CABG decreased from 5418 to 5206. Conclusions: From 2007 to 2017, rates of RA trebled in Australia. This is despite stable rates of PCI and a fall in rates of CABG. There are several clinical explanations for this trend.
Battered and Brain Injured: Traumatic Brain Injury Among Women Survivors of Intimate Partner Violence—A Scoping Review
Authors: Haag Halina (Lin) , Jones Dayna , Joseph Tracey , Colantonio Angela 
Published: June 2019

Objectives: The objective of this scoping review is to examine the extent, range, and nature of literature targeting health-care professionals on the prevalence and outcome of intimate partner violence (IPV)-related traumatic brain injury (TBI). The purpose is to gain an understanding of prevalence, investigate screening tool use, generate IPV/TBI-specific support recommendations, and identify suggestions for future research. Method: The review was guided by Arksey and O’Malley’s five stages for conducting a scoping review. A comprehensive search of nine databases revealed 1,739 articles. In total, 42 published research papers that focused specifically on TBI secondary to IPV were included in the study. Synthesis: The literature reports inconsistencies in prevalence rates from IPV-related TBI. There are no current standardized screening practices in use, though the literature calls for a specialized tool. Frontline professionals would benefit from education on signs and symptoms of IPV-related TBI. Empirical studies are needed to generate reliable data on prevalence, experience, and needs of brain-injured survivors of TBI. Conclusions: Findings from this study demonstrate the need for the development of an IPV-sensitive screening tool, more accurate data on prevalence, an interprofessional approach to care, and raised awareness and education on the diffuse symptoms of IPV-related TBI.
Lessons learned from a rapid implementation of a ventilator-associated pneumonia prevention bundle
Authors: Ladbrook Elyse , Bouchoucha Stéphane L. , Hutchinson Ana 
Published: June 2019

Background: Ventilator-associated pneumonia (VAP) is a common avoidable healthcare associated infection in ventilated critical care patients that can have a detrimental impact on patient recovery. To increase uptake at a local level, care bundles should be designed and implemented in collaboration with the end-users who will implement the bundle into practice. Aim/objective: The aim in this study was to evaluate critical care nurses’ perceptions of the usability of a respiratory care bundle as an effective approach to VAP prevention. Methods: An exploratory descriptive qualitative study was conducted. A respiratory care bundle consisting of five components was implemented over a 4-week period. Following implementation, a focus group and semi-structured interviews were conducted to obtain nurses’ feedback on the useability of the care bundle. Seven intensive care nurses caring for ventilated patients participated in the study. Findings/results: Participants confirmed that using a care bundle provided a structured approach to nursing care of a ventilated patient and that the use of checklist reminders at the bedside was useful in a busy practice environment. Barriers to uptake and implementation of the bundle were that the unit culture did not prioritise preventative care and the need for a structured interdisciplinary approach to sedation and weaning of mechanical ventilation. Discussion: To successfully imbed all elements of a respiratory care bundle into practice; an interdisciplinary approach is needed in which there is a strong emphasis on preventative care. These findings highlight the advantages of involving end-users in the development of strategies to decrease VAP.
Bladder cancer in the elderly: A retrospective analysis of bladder cancer in individuals older than 85 years
Authors: Parsons SR , Hill GT , Warren KS , Burden HP 
Published: June 2019

Introduction: Current life expectancy in the United Kingdom is 79.2 years in men and 82.9 years in women. Average age at diagnosis of bladder cancer is 73 years, but incidence continues to rise with age. Elderly patients represent a unique cohort of patients; they often have multiple medical co-morbidities, and may have different wishes and treatment aims as opposed to younger patients. We describe our current bladder cancer practice in patients older than 85 years. Methods: A retrospective review was conducted of patients older than 85 years, first diagnosed with bladder cancer between December 2012 and June 2016. Results: A total of 102 patients were analysed from our database. Mean age at diagnosis was 88.34 years. Staging at diagnosis was: 75 non–muscle-invasive bladder cancer (NMIBC) (17 low, 13 intermediate, 45 high risk), 23 muscle-invasive bladder cancer (MIBC), and four metastatic disease. Of patients with NMIBC, 29/75 patients had a recurrence, 4/75 were upstaged, and 9/75 progressed to MIBC. Twenty-nine of 75 of the NMIBC patients declined treatment or ongoing surveillance. Overall, 53% (53/102) have died of any cause, with a mean of 2.0 years since diagnosis, 31 of bladder cancer. In NMIBC patients, 38.7% (29/102) have died of any cause since diagnosis, at a mean interval of 1.8 years following diagnosis. Conclusion: In our cohort of bladder cancer patients older than 85 years, there is a high all-cause mortality rate within a relatively short time period following diagnosis. These data should aid well-informed discussions with our elderly bladder cancer patients and their relatives when considering treatment and surveillance options. Level of evidence: Not applicable for this single centre audit.
Resistance of coated polyetheretherketone lumbar interbody fusion cages against abrasion under simulated impaction into the disc space
Authors: Kienle Annette , Krieger Alexander , Willems Karel , Wilke Hans-Joachim 
Published: June 2019

In order to improve osseointegration, polyetheretherketone (PEEK) interbody fusion cages are frequently surface coated. The bonding strength of the coatings is mostly investigated under unrealistic loading conditions. To close this gap, in this study, uncoated and coated cages were loaded in a clinical setup in order to investigate their real resistance against abrasion. Six uncoated, six calcium phosphate (CaP) nanocoated, and six titanium (Ti) nanocoated PEEK cages were tested in this study. The experimental setup was designed to mimic cage impaction into the intervertebral disc space using polyurethane (PU) foam blocks as vertebral body substitutes. The cage surface was inspected before and after impaction, and their weight was measured. Impaction resulted in abrasion at the tip of the ridges on the implant surface. The mean weight loss was 0.39 mg for the uncoated cages, 0.57 mg for the CaP nanocoated cages, and 0.75 mg for the Ti nanocoated cages. These differences were statistically significant. In conclusion, differences between the three cage types were found concerning the amount of abrasion. However, all three cages lost less weight than a comparative Ti plasma spray coated cage, which showed a mean weight loss of 2.02 mg. This may be because the plasma spray coating is significantly thicker than the two nanocoatings. If compared with the permitted amount of weight loss derived from an FDA guidance document, which is approximately 1.7 mg, the wear of the Ti plasma spray coated cage is above this limit, whereas the wear for all other cage types is below.
Electromagnetic waves scattering from a sphere of complex conjugate medium
Authors: Illahi Ahsan , Bashir M. , Alkanhal Majeed A. S. , Khatoon Sadia , Ghaffar Abdul , Khan Y. 
Published: June 2019

AbstractA boundary value problem involving the scattering of electromagnetic waves from a sphere of complex conjugate medium (CCM) is studied. The sphere is placed in free space. The source of excitation for the sphere in our case is a plane wave. Incident, scattered and transmitted fields are formulated. The unknown coefficients in the scattered and transmitted fields are found using boundary conditions. From these electromagnetic fields, the Mie efficiencies are determined. The technique used in studying the scattering of electromagnetic waves from CCM is analytical and a closed form solution is obtained. It is shown by numerical results that the scattering is enhanced in case of CCM sphere as a target. Results for the limiting cases are also derived to compare the validity of our formulation with the published work.
Female survivors of intimate partner violence and risk of depression, anxiety and serious mental illness
Authors: Chandan Joht Singh , Thomas Tom , Bradbury-Jones Caroline , Russell Rebecca , Bandyopadhyay Siddhartha , Nirantharakumar Krishnarajah , Taylor Julie 
Published: June 2019

BackgroundInternationally, intimate partner violence (IPV) cohorts have demonstrated associations with depression and anxiety. However, this association has not yet been described in a UK population, nor has the association with serious mental illness (SMI).AimsTo explore the relationship between IPV exposure and mental illness in a UK population.MethodWe designed a retrospective cohort study whereby we matched 18 547 women exposed to IPV to 74 188 unexposed women. Outcomes of interest (anxiety, depression and SMI) were identified through clinical codes.ResultsAt baseline, 9174 (49.5%) women in the exposed group had some form of mental illness compared with 17 768 (24.0%) in the unexposed group, described as an adjusted odds ratio of 2.62 (95% CI 2.52–2.72). Excluding those with mental illness at baseline, 1254 exposed women (incidence rate 46.62 per 1000 person-years) went on to present with any type of mental illness compared with 3119 unexposed women (incidence rate 14.93 per 1000 person-years), with an aIRR of 2.77 (95% CI 2.58–2.97). Anxiety (aIRR 1.99, 95% CI 1.80–2.20), depression (aIRR 3.05, 95% CI 2.81–3.31) and SMI (aIRR 3.08, 95% CI 2.19–4.32) were all associated with exposure to IPV.ConclusionsIPV remains a significant public health issue in the UK. We have demonstrated the significant recorded mental health burden associated with IPV in primary care, at both baseline and following exposure. Clinicians must be aware of this association to reduce mental illness diagnostic delay and improve management of psychological outcomes in this group of patients.
Familial X-Linked Acrogigantism: Postnatal Outcomes and Tumor Pathology in a Prenatally Diagnosed Infant and His Mother
Authors: Wise-Oringer Brittany K , Zanazzi George J , Gordon Rebecca J , Wardlaw Sharon L , William Christopher , Anyane-Yeboa Kwame , Chung Wendy K , Kohn Brenda , Wisoff Jeffrey H , David Raphael , Oberfield Sharon E 
Published: June 2019

AbstractContextX-linked acrogigantism (X-LAG), a condition of infant-onset acrogigantism marked by elevated GH, IGF-1, and prolactin (PRL), is extremely rare. Thirty-three cases, including three kindreds, have been reported. These patients have pituitary adenomas that are thought to be mixed lactotrophs and somatotrophs.Case DescriptionThe patient’s mother, diagnosed with acrogigantism at 21 months, underwent pituitary tumor excision at 24 months. For more than 30 years, stable PRL, GH, and IGF-1 concentrations and serial imaging studies indicated no tumor recurrence. During preconception planning, X-LAG was diagnosed: single-nucleotide polymorphism microarray showed chromosome Xq26.3 microduplication. After conception, single-nucleotide polymorphism microarray on a chorionic villus sample showed the same microduplication in the fetus, confirming familial X-LAG. The infant grew rapidly with rising PRL, GH, and IGF-1 concentrations and an enlarging suprasellar pituitary mass, despite treatment with bromocriptine. At 15 months, he underwent tumor resection. The pituitary adenoma resembled the mother’s pituitary adenoma, with tumor cells arranged in trabeculae and glandular structures. In both cases, many tumor cells expressed PRL, GH, and pituitary-specific transcription factor-1. Furthermore, the tumor expressed other lineage-specific transcription factors, as well as SOX2 and octamer-binding transcription factor 4, demonstrating the multipotentiality of X-LAG tumors. Both showed an elevated Ki-67 proliferation index, 5.6% in the mother and 8.5% in the infant, the highest reported in X-LAG.ConclusionsThis is a prenatally diagnosed case of X-LAG. Clinical follow-up and biochemical evaluation have provided insight into the natural history of this disease. Expression of stem cell markers and several cell lineage-specific transcription factors suggests that these tumors are multipotential.