bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERBANDINGAN SIFAT GELATIN YANG BERASAL DARI KULIT IKAN PATIN (Pangasius hypophthalmus) DAN GELATIN YANG BERASAL DARI KULIT IKAN KOMERSIL
Authors: Oktaviani Ira , Perdana Fitra , Nasution Azlaini Yus 
Published: September 2019

Gelatin is widely used in the food, pharmaceutical, and cosmetic industries. The demand for gelatin increases every year, gelatin derived from pigs and cows is the main source of gelatin in the market. Gelatin that is sourced from other animals such as from poultry and fish is only about 1%.
Gelatin from fish becomes a better prospect to develop. Gelatin raw materials can be obtained from the skin, bones, and fish fins. Fish skin is a waste processing of fishery products, such as in the manufacture of meatballs, crackers, and so forth, which has no economic value and even harmful. “Patin” catfish is one of the most developed fish due to the high demand from both domestic and international market. Kampar Regency Riau Province is one of the centers of “patin”catfish development in Indonesia. Gelatin is valuable for the pharmaceutical and cosmetic industries because it is used in various formulations. This study aims to see the quality of gelatin obtained from catfish skin obtained by acidification process which will be continued utilization as additional material in cosmetic manufacture.
In this study, gelatin obtained from “patin” catfish skin extraction was evaluated organoleptically including odor, taste, and shape, moisture content, ash content, pH, and protein contained therein, which results were compared with gelatin derived from commercial fish skins. In organoleptis, the resulting odor is dry powder, odorless, and tasteless, the average water content of commercial fish gelatin is 10.03% and of catatin gelatin is 9.92%, the mean ash content obtained from commercial gelatin fish 2,1958% and “patin” catfish gelatin equal to 0,15%, average protein content on gelatin of commercial fish equal to 85,68% and from “patin” catfish gelatin equal to 88,38%, pH obtained in commercial fish gelatin 6.4 and from “patin”catfish gelatin of 5.7.
Are Complex Multiple-Choice Options More Difficult and Discriminating Than Conventional Multiple-Choice Options?
Authors: Tripp Alice , Tollefson Nona 
Published: September 2019

ABSTRACT
Differences in item difficulty between conventional and complex multiple-choice (M-C) items measuring objectives written at the six levels of the cognitive domain and three content areas within a basic health professions subject matter area were investigated. Conventional and complex M-C items were also compared in terms of item discrimination.
Five hundred fifteen senior baccalaureate nursing students randomly responded to one of two packages of 18 oneitem pharmacology achievement tests. Items in the two packages were matched in all respects except for the type of option.
A 2 × 3 × 6 repeated measures ANCOVA with method of pharmacology as the covariate showed a statistically significant (p < .01) interaction of option × content × cognitive level. Scheffé tests revealed that complex items were more difficult than conventional option items at the knowledge level only across all content areas investigated. No statistically significant differences were found between the two option types discriminating ability.
Results of this research question the validity of the assumption that complex items are more difficult and discriminating than conventional M-C items.
PDE4B gene polymorphism in Russian patients with panic disorder
Authors: Malakhova Alena V , Rudko Olga I , Sobolev Vladimir V , Tretiakov Artemii V , Naumova Elena A , Kokaeva Zarema G , Azimova Julia E , Klimov Eugene A 
Published: September 2019

Abstract
Background Panic disorder is a complex disease of unclear etiology but with an apparent genetic component. PDE4B gene product is involved in many cell processes owing to its function-regulation of the level of a second messenger cAMP. PDE4B gene polymorphism has been shown to be associated with some mental disorders including panic disorder.
Aims The goal of our study was to evaluate the role of 3 SNPs in the PDE4B gene in the development of panic disorder.
Methods 94 patients diagnosed with panic disorder according to the DSM-IV criteria were enrolled in the study. The population control group included 192 subjects. Genotyping was carried out by real-time PCR with TaqMan probes.
Results The investigated substitutions are not associated with panic disorder in general and in female/male cohorts (p > 0.05). The analysis of complex genotypes demonstrated two protective complex genotypes (rs1040716:A, T + rs10454453:A + rs502958:A and rs1040716:A, T + rs502958:A) associated with panic disorder in general regardless of the patient's gender (p < 0.05). These genotypes did not correlate with the patient's sex.
Conclusions We found two complex protective genotypes associated with panic disorder. This can be due to the fact that predisposition to the disease are associated with other genes, while PDE4B gene polymorphism reduces their effect.
Risk Attitudes and Financial Profitability of Tomato Farmers - A Study in Bangladesh
Authors: Mitra S. , Sharmin S. 
Published: September 2019

Purpose: Tomato production in the world has increased tremendously within last few decades. Nevertheless, tomato farmers are facing production, market, price and financial uncertainty. Management of these risks is greatly influenced by their attitudes towards risk. So, the objective of this study is to determine the risk attitude and profitability of tomato farmers in Bangladesh.Research Method: Sixty sample respondents of tomato farmers were selected from Mymensingh district. The Safety-First principle was used to estimate risk attitude coefficient while obit regression model was utilized to estimate the factors affecting risk attitudes of tomato farmers. In addition, financial profitability was analyzed from different points of view.Findings: Most of the tomato farmers were risk averse. Results find that only 18% of farmers were risk preferring while 42% of farmers were risk averse. Risk preferences of farmers increase with training and education while risk preference decrease with age and experience. Training and education help to understand the importance of receiving newly introduced technology, timely application of seed, irrigation and fertilizer. Education assists to earn from diversified sources that make them risk preferred. The benefit cost ratio (BCR) of tomato farming was 2.31 indicating that tomato farming is profitable.Research Limitation: A small sample size was used for this study. Therefore, policy makers should be cautious to generalize the results to a wide context of tomato farmers in developing countries.Originality/ Value: Productivity and profitability of tomato farmers can be improved if farmers can manage different risks and uncertainty associated with production practices.
Cutaneous wound healing: Current concepts and advances in wound care
Authors: Klein Kenneth C , Guha Somes Chandra 
Published: September 2019

ABSTRACTA non-healing wound is defined as showing no measurable signs of healing for at least 30 consecutive treatments with standard wound care.[1] It is a snapshot of a patient’s total health as well as the ongoing battle between noxious factors and the restoration of optimal macro and micro circulation, oxygenation and nutrition. In practice, standard therapies for non-healing cutaneous wounds include application of appropriate dressings, periodic debridement and eliminating causative factors.[2] The vast majority of wounds would heal by such approach with variable degrees of residual morbidity, disability and even mortality. Globally, beyond the above therapies, newer tools of healing are selectively accessible to caregivers, for various logistical or financial reasons. Our review will focus on the use of hyperbaric oxygen therapy (HBOT), as used at our institution (CAMC), and some other modalities that are relatively accessible to patients. HBOT is a relatively safe and technologically simpler way to deliver care worldwide. However, the expense for including HBOT as standard of care for recognized indications per UHMS(Undersea and Hyperbaric Medical Society) may vary widely from country to country and payment system.[3] In the USA, CMS (Centers for Medicare and Medicaid Services) approved indications for HBOT vary from that of the UHMS for logistical reasons.[1] We shall also briefly look into other newer therapies per current clinical usage and general acceptance by the medical community. Admittedly, there would be other novel tools with variable success in wound healing worldwide, but it would be difficult to include all in this treatise.
Enhancing dermal and bone regeneration in calvarial defect surgery
Authors: Zanotti Bruno , Zingaretti Nicola , Almesberger Daria , Verlicchi Angela , Stefini Roberto , Ragonese Mauro , Guarneri Gianni Franco , Parodi Pier Camillo 
Published: September 2019

ABSTRACT
Introduction: To optimize the functional and esthetic result of cranioplasty, it is necessary to choose appropriate materials and take steps to preserve and support tissue vitality. As far as materials are concerned, custom-made porous hydroxyapatite implants are biomimetic, and therefore, provide good biological interaction and biointegration. However, before it is fully integrated, this material has relatively low mechanical resistance. Therefore, to reduce the risk of postoperative implant fracture, it would be desirable to accelerate regeneration of the tissues around and within the graft. Objectives: The objective was to determine whether integrating growth-factor-rich platelet gel or supportive dermal matrix into hydroxyapatite implant cranioplasty can accelerate bone remodeling and promote soft tissue regeneration, respectively. Materials and Methods: The investigation was performed on cranioplasty patients fitted with hydroxyapatite cranial implants between 2004 and 2010. In 7 patients, platelet gel was applied to the bone/prosthesis interface during surgery, and in a further 5 patients, characterized by thin, hypotrophic skin coverage of the cranial lacuna, a sheet of dermal matrix was applied between the prosthesis and the overlying soft tissue. In several of the former groups, platelet gel mixed with hydroxyapatite granules was used to fill small gaps between the skull and the implant. To confirm osteointegration, cranial computed tomography (CT) scans were taken at 3-6 month intervals for 1-year, and magnetic resonance imaging (MRI) was used to confirm dermal integrity. Results: Clinical examination performed a few weeks after surgery revealed good dermal regeneration, with thicker, healthier skin, apparently with a better blood supply, which was confirmed by MRI at 3-6 months. Furthermore, at 3-6 months, CT showed good biomimetism of the porous hydroxyapatite scaffold. Locations at which platelet gel and hydroxyapatite granules were used to fill gaps between the implant and skull appeared to show more rapid integration of the implant than untreated areas. Results were stable at 1-year and remain so to date in cases where follow-up is still ongoing. Conclusions: Bone remodeling time could be reduced by platelet gel application during cranioplasty with porous hydroxyapatite implants. Likewise, layering dermal matrix over such implants appears to promote dermal tissue regeneration and the oshtemo mimetic process. Both of these strategies may, therefore, reduce the likelihood of postsurgical fracture by promoting mechanical resistance.
Transoral versus extraoral approach for mandibular angle fractures: A comparative study
Authors: Devireddy Sathya Kumar , Kumar R.V. Kishore , Gali Rajasekhar , Kanubaddy Sridhar Reddy , Dasari Mallikarjuna Rao , Akheel Mohammad 
Published: September 2019

ABSTRACT
Introduction: Mandibular fractures represent approximately two-thirds of all the maxillofacial fractures (nearly 70%) out of which fractures of mandibular angle represent for 26-35%. Aim of the Study: The aim of this study is to compare the transoral and extraoral (submandibular) approaches for fixation of mandibular angle fractures. Objectives of Study: The objectives of the following study are to evaluate ease of accessibility, time taken for the procedure, ease of anatomic reduction and complications. Materials and Methods: A prospective study was carried out in 30 patients reporting to the Department of Oral and Maxillofacial surgery, Narayana Dental College and Hospital, Nellore, Andhra Pradesh during the period of months from November 2011 to August 2013 who were randomly divided in two groups based on computer generated simple randomization chart. Group I patients underwent transoral reduction and fixation and Group II patients underwent extraoral reduction and fixation. The ease of accessibility was analysed by visual analogue scale by the operating surgeon, time taken from incision to closure with digital clock, difficulty level index of surgeon based on the time taken for the procedure and approach related complications. Results: The ease of accessibility in Group I was good in 53.3% while in Group II patients approached extraorally it was good in 86.7%. Group I patients approached transorally showed a mean of 49.7 min while that of Group II patients approached extraorally showed a mean of 73.4 min. Group I had a minimum difficulty level index in 60%, moderate difficulty level in 33.3% and severe difficulty level in 6.7% while Group II had a minimum and moderate difficulty level in 46.7% and severe difficulty level in 6.7%. There was 1 (6.7%) complication reported in each group. Conclusion: The statistical analysis of this study concludes that fracture line starting anterior to mandibular third molar and ending at anteroinferior border of the insertion of the masseter muscle or posterior body of mandible can be approached transorally. Fracture line starting posterior or distal to the third molar or posterior to the insertion of the masseter muscle to the angle of the mandible or fracture line extending high in the ramus, extraoral approach provides a better choice for reduction and fixation of the fractured segments with restoration of anatomical and functional occlusion.
Effect of intense pulsed light on immature burn scars: A clinical study
Authors: Sarkar Arindam , Dewangan Yatindra Kumar , Bain Jayanta , Rakshit Pritha , Dhruw Krishnanand , Basu Sandip Kanti , Saha Jayanta Kumar , Majumdar Bijay Kumar 
Published: September 2019

ABSTRACT
Introduction: As intense pulsed light (IPL) is widely used to treat cutaneous vascular malformations and also used as non-ablative skin rejunuvation to remodel the skin collagen. A study has been undertaken to gauze the effect of IPL on immature burn scars with regard to vascularity, pliability and height. Materials and Methods: This study was conducted between June 2013 and May 2014, among patients with immature burn scars that healed conservatively within 2 months. Photographic evidence of appearance of scars and grading and rating was done with Vancouver Scar Scale parameters. Ratings were done for both case and control scar after the completion of four IPL treatment sessions and were compared. Results: Out of the 19 cases, vascularity, pliability and height improved significantly (P < 0.05) in 13, 14 and 11 scars respectively following IPL treatment. Conclusions: Intense pulsed light was well-tolerated by patients, caused good improvement in terms of vascularity, pliability, and height of immature burn scar.
Closure of chronic non healing ankle ulcer with low level laser therapy in a patient presenting with thalassemia intermedia: Case report
Authors: Dixit Snehil , Agrawal Parul Raj , Sharma Dinesh Kumari , Singh Ravindra Pratap 
Published: September 2019

ABSTRACTIn this single case study, the possible effect of low-level laser therapy (LLLT) was explored in the form of light emitting diodes on a chronic non-healing wound of 6 months duration in an 18-year-old male patient suffering from thalassemia intermedia. After irradiation, with LLLT dosage of 17.3 J/cm 2 for 8 min for 2 weeks duration followed by proliferative dosage of 8.65-4.33 J/cm 2 for 4 min from 3 rd week to 6 th week for 2 min along with antibiotics vancomycin (15 mg/kg) and a combination of amoxicillin and clavulanic acid (1 g). Proliferation of healthy granulation tissue was observed with decrease in score of pressure ulcer scale with complete re-epithelialization eventually LLLT irradiation could be a novel method of treatment for chronic non-healing wound in a thalassemia intermedia patient and an useful adjunct to standard care of treatment of pressure ulcers. It is postulated that LED irradiation augments wound healing with an early closure and no recurrence at the irradiated site even after follow up of 6 months.
Multiple bowel perforation and necrotising fasciitis secondary to abdominal liposuction in a patient with bilateral lumbar hernia
Authors: Dellière Vincent , Bertheuil N. , Harnois Y. , Thiènot S. , Gèrard M. , Robert M. , Watier E. 
Published: September 2019

ABSTRACTWe present a rare complication of abdominal liposuction: bowel perforation and necrotizing fasciitis. Because of bilateral lumbar hernia, a 56-year-old woman had caecum and descending colon perforation during lipoplasty. She had septic shock syndrome at her admission. The authors treated this complex wound with several debridement, omental flap, NPWT and split-thickness skin graft. The incidence of abdominal wall perforation with visceral injury is 14 in 100,000 liposuctions performed. There are only 12 cases of bowel perforation in literature but this complication is probably underestimated. Prompt surgical debridement is absolutely mandatory in this life threatening scenario. Lumbar hernia is very rare and should be ruled out before every abdominal liposuction clinically or with imaging modalities.
Giant rhinophyma: Excision with coblation assisted surgery
Authors: Sahin Caner , Turker Mesut , Celasun Bulent 
Published: September 2019

ABSTRACTAn 83-year-old man presented with an unusually severe case of rhinophyma. Giant rhinopyhma is very rare in literature. The giant lesion was widely excised using sharp surgical incision and coblation assisted surgery. Using direct coblation to the nasal dorsum may cause edema in the surrounding tissue. There was minimal edema in surrounding tissue using this technique. A full thickness-skin graft was applied after excision. Cosmetic and functional postoperative results were satisfactory.
Pedicle streaking: A novel and simple aid in pedicle positioning in free tissue transfer
Authors: Aggarwal Aditya , Singh Hardeep , Mahendru Sanjay , Brajesh Vimalendu , Singh Sukhdeep , Khare Ashish , Kothari Umang , Khazanchi Rakesh Kumar 
Published: September 2019

ABSTRACT
Introduction: The pedicle positioning in free tissue transfer is critical to its success. Long thin pedicles are especially prone to this complication where even a slight twist in the perforator can result in flap loss. Pedicles passing through the long tunnels are similarly at risk. Streaking the pedicle with methylene blue is a simple and safe method which increases the safety of free tissue transfer. Materials and Methods: Once the flap is islanded on the pedicle and the vascularity of the flap is confirmed, the pedicle is streaked with methylene blue dye at a distance of 6-7 mm. The streaking starts from the origin of the vessels and continued distally on to the under surface of flap to mark the complete course of the pedicle in alignment. The presence of streaking in some parts and not in rest indicates twist in the pedicle. Observation and Results: Four hundred and sixty five free flaps have been done at our centre in the last 5 years. The overall success rate of free flaps is 95.3% (22 free flap failures). There has not been a single case of pedicle twist leading to flap congestion and failure. Conclusion: This simple and novel method is very reliable for pedicle positioning avoiding any twist necessary for successful free tissue transfer.
A report of 2 patients with transient blindness following Le Fort I osteotomy and a review of past reported cases
Authors: Mathew Philip , Adenwalla Hirji Sorab , Narayanan Puthucode V , Nyamu Emily 
Published: September 2019

ABSTRACTBlindness following a LeFort I osteotomy is a rare but extremely serious complication. Ten cases have been reported to date. None of these patients recovered vision. Optic neuropathy is believed to be the cause but the exact mechanism has not been settled. We report the first, and the only two, documented cases of complete loss of vision that recovered subsequently. The first patient was a 19-year-old male with repaired bilateral cleft lip and palate. He developed loss of vision in the right eye on the second postoperative day. The second patient was a 22-year-old male with repaired unilateral cleft lip and palate. He developed complete loss of vision in the left eye on the day of surgery. Both these patients underwent ongoing studies, which did not show any abnormalities. Both were treated with methylprednisolone. Both the patients gradually showed improvement in their vision. The first patient recovered normal vision several months postoperatively. The second patient’s vision improved to 4/60 by 4 months postoperatively. We discuss the probable mechanisms of optic nerve injury and also the possible reasons why sight was restored in these patients. This is a rare but serious complication following a fairly common procedure. Through this article we wish to create an awareness of this complication and also a possible way of avoiding such a disaster.
A simple external tissue expansion technique based on viscoelastic properties of skin to attain direct closure of a large scalp defect: A case report
Authors: Ratnam Bandikatla Venkata 
Published: September 2019

ABSTRACT
Background: Direct closure of large scalp defects is not an easy task. Complicated flap designs or staged surgeries over a period of 6 months are often required. A case of a large scalp defect that was closed directly in 3 months by applying a simple external tissue expansion technique is presented in this report. Patient Profile: A 28-year-old male patient presented with a painful swelling of about 13 cm × 14 cm, on frontoparietal scalp. A biopsy done elsewhere reported it to be a neurofibroma. He sought tumour excision and scalp defect coverage by hair-bearing scalp in a period of less than 5 months. Materials and Methods: The tumour was excised and the adjacent scalp was gradually expanded with the help of an external fixator. The patient had immediate pain relief after excision. The goal of repairing scalp defect and replacing it with hairy scalp was achieved in 3 months. Conclusion: The mechanical device required for this technique is relatively easily accessible. It is not difficult to achieve desirable outcomes, and the same can be applied to large wounds on other areas.
Polynomials from Combinatorial -theory
Authors: Monical Cara , Pechenik Oliver , Searles Dominic 
Published: September 2019

AbstractWe introduce two new bases of the ring of polynomials and study their relations to known bases. The first basis is the quasi-Lascoux basis, which is simultaneously both a $K$-theoretic deformation of the quasi-key basis and also a lift of the $K$-analogue of the quasi-Schur basis from quasi-symmetric polynomials to general polynomials. We give positive expansions of this quasi-Lascoux basis into the glide and Lascoux atom bases, as well as a positive expansion of the Lascoux basis into the quasi-Lascoux basis. As a special case, these expansions give the first proof that the $K$-analogues of quasi-Schur polynomials expand positively in multifundamental quasi-symmetric polynomials of T. Lam and P. Pylyavskyy.The second new basis is the kaon basis, a $K$-theoretic deformation of the fundamental particle basis. We give positive expansions of the glide and Lascoux atom bases into this kaon basis.Throughout, we explore how the relationships among these $K$-analogues mirror the relationships among their cohomological counterparts. We make several “alternating sum” conjectures that are suggestive of Euler characteristic calculations.