bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biosorption of lead(II) from aqueous solution by lactic acid bacteria
Authors: Dai Q. H. , Bian X. Y. , Li R. , Jiang C. B. , Ge J. M. , Li B. L. , Ou J. 
Published: February 2019

Abstract
The biosorption of Pb(II) from aqueous solutions by lactic acid bacterium, Lactobacillus brevis, was studied. The effects of initial pH, contact time, initial Pb(II) concentration, bacterial concentration, rotation speed and temperature of biosorption of Pb(II) from aqueous solutions were investigated. The optimal condition for Pb2+ ions adsorption was observed at pH 6, with the rotational speed of 120 rpm.min−1, bacterial concentration of 3 g.L−1, temperature of 40 °C and contact time of 12 h. The correlation regression coefficients showed that the biosorption process can be well fitted with the Redlich-Peterson, Langmuir, Freundlich and Temkin isotherm models. The equilibrium adsorption capacity reached 53.632 mg.g−1. Binding energy value was 0.264 kJ/mol, which indicated that the adsorption process seemed to involve chemisorption and physisorption. Kinetics of adsorption was found to fit well with the pseudo-second-order and Elovich kinetic equations. Thermodynamic parameters revealed the feasibility, spontaneity and endothermic nature of adsorption.
Возможности развития регуляторных функций в игровой деятельности: теоретический обзор
Authors: Veraksa Aleksandr N. , Bukhalenkova Daria А. , Yakupova Vera А. 
Published: February 2019

Introduction. Play is a symbolic space through which children cognize the world around them and master their mental processes. This study considers the potential of play activity for the development of various higher mental functions in preschool-age children.
Theoretical Basis. This section describes working memory, inhibition, and cognitive flexibility as components of executive functions and demonstrates how they are involved in play activity.
Results. This section summarizes: a) correlation studies on the relationship between self-regulation and play; and b) formative experiments that used play activity for the development of executive functions. Correlation studies showed that free play with peers has a complex structure and includes various aspects (role-taking, play substitution of objects and actions, and interaction with peers), which are differently related to the development of executive functions in preschool children. Attention is also given to studies that establish the relationship between children’s imagination in a play situation and the development of executive functions. Formative experiments indicated that a certain level of the development of executive functions is important for the implementation of play activities. At the same time, play activity is a mechanism for the development of executive functions.
Discussion. The authors concentrate on limitations of the analyzed studies. The major drawback they identified is that previous studies of play activity examined its certain components in isolation (object substitution, role-taking, and imaginary situation). This review calls for further research that would identify a number of parameters and undertake a long-term observation to describe play activity of every individual child. Play activity is not simply a context for children’s emotional involvement; it is also important for the symbolic situations of the play to be close to their interests. Thus, the authors establish the complexity of organizing the development of executive functions within formative experiments using play activity. The study emphasizes the great potential of this direction of research.
Investigation of Potential Paraoxonase-I Inhibitors by Kinetic and Molecular Docking Studies: Chemotherapeutic Drugs
Authors: Türkeş Cüneyt 
Published: February 2019

Background:Metabolic processes in living organisms are closely related to the catalytic activity of enzymes. Changes in enzyme activity cause various diseases e.g., neurological, cancer, metabolic and cardiovascular. Most of the current therapeutic drugs available in clinical utilization function as enzyme inhibitors.Objective:The main goal of the current study to contribute to this growing drug design area (such as medication discovery and development) by investigating protein-drug interactions.Methods:The paraoxonase-I (PON1) enzyme was purified from human serum by using different and simple chromatographic techniques. Additionally, it was investigated inhibition effects of some chemotherapeutic drugs on the PON1.Results:The purification results for PON1 depicted a 3880.83 EU/mg proteins specific activity and the molecular weight was calculated as 43 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. These drugs found to strongly inhibit PON1, with IC50 values ranging from 0.222±0.002 to 688.300±0.897 µM. Ki constants for vincristine sulfate, epirubicin hydrochloride, and doxorubicin hydrochloride were determined to be 0.235±0.032 µM, 221.400±29.270 µM, and 913.300±201.000 µM, respectively.Conclusion:These drugs showed in competitive inhibition. Also, the molecular docking poses of these agents inside the catalytic sites of 1V04 and 3SRE were analysis.
VITAMIN A OF EEL FISH (ANGUILLA MARMORATA) FROM PALU RIVER AND POSO LAKE
Authors: Jamaluddin Jamaluddin , Widodo Agustinus , Mufliha Nurul 
Published: February 2019

Background & Objective: Eel fish (Anguilla marmorata) has high nutritional or nutrition advantages such as protein, minerals, fatty acids and one of them is vitamin A. This study aims to compare the amount vitamin A of eel fish (Anguilla marmorata) phase glass eel, yellow eel, silver eel from Palu River and Lake Poso. Materials and Methods: The materials used in this research are eel fish (Anguilla marmorata) Glass eel, Yellow eel, Silver eel size from Palu River and Lake Poso, Ethanol, KOH, n-Hexane, BHT (Butyl Hydroxyl Toluene), Methanol. The sampling technique uses purposive sampling based on the type of weight, size and location of the taking. The method used is High Performance Liquid Chromatography (HPLC) where previously conducted saponification test (saponification) on sample of eel fish. Results: The result of vitamin A test on eel fish from Palu River phase of glass eel is 4.01 mg / kg (1336,67 IU / 100 gram), yellow eel 7,26 mg / kg (2420 IU / 100 gram), silver eel equal to 9.73 mg / kg (3243,34 IU / 100 gram). Vitamin A in eels from Lake Poso phase of glass eel of 0.22 mg / kg (73.34 IU / 100 gram), yellow eel 7.16 mg / kg (2386.67 IU / 100 gram), silver eel of 11 , 3 mg / kg (3766.67 IU / 100 gram). Conclusion: vitamin A of eel fish content from Palu River and Lake Poso were significantly different, which was based on p <0,05
ANALYSIS OF MACRO NUTRITION IN DUO FISH (PENJA) BLACK AND WHITE AS FOOD LOCAL PALU
Authors: Jayadi Yusma Indah , Rahman Abd 
Published: February 2019

Background & Objective: Food Pattern of Central Sulawesi Expectation has not fulfilled suggestion, potential of food product of Central Sulawesi one of them is fish duo, or commonly called penja. This study aims to analyze the nutritional content of fish meal duo which is a source of protein in the food potential of Palu City. Materials and Methods: The type of this research is descriptive laboratory, conducted in Nutrition Laboratory of Animal Husbandry for fish feed and proximate analysis, research conducted from October until November 2016. Sampling technique using purposive sampling, fish duo (penja) sold in market Inpres. Production of duo fish meal (penja) in Animal Husbandry Laboratory and further measured proximal level of both samples. Results: Black and white duo fish (penja) for moisture content have fulfilled the SNI of quality I that is 5.37% and 6.3%, the protein content has fulfilled the second quality SNI that is 56.6% and 54.19%, the fat content that meet the SNI the quality of I and II is 8.4% and 9.72%, the fiber content meets the SNI of quality II is 2.06% and 2.61% and the ash content meets the SNI of quality I is 10.5% and 8.9%. Conclusion: Black and white duo fish powder is higher in protein than starch. This research shows macro fish macro nutrition has fulfilled SNI I and quality II, protein is superior to fish meal
HIPERGLIKEMIA SEBAGAI PREDIKTOR KEBERHASILAN PENGOBATAN PASIEN DENGAN SINDROM KORONER AKUT DI RSUD X SURAKARTA
Authors: Mahmuda Iin Novita Nurhidayati , Rezki Yuniana Nur , Priscillah Wildan 
Published: February 2019

ABSTRAK Sindrom Koroner Akut atau acute coronary syndrome (ACS) dengan hiperglikemia pada saat masuk memiliki rerata mortalitas yang lebih tinggi, pada penelitian terbaru. Hiperglikemia pada pasien dengan ACS digambarkan sebagai respon akut dari keadaan hiperadrenergik dengan peningkatan risiko trombosis, sehingga bisa memperburuk kondisi pasien ACS selama dirawat di rumah sakit. Tujuan penelitian ini untuk mengetahui perbedaan lama tinggal dan mortalitas pada pasien ACS dengan stres hiperglikemia dan tanpa hiperglikemia stres. Jenis penelitian ini adalah penelitian observasional analitik dengan pendekatan cross sectional. Subjek penelitian adalah pasien ACS non-diabetes di RSUD X Surakarta. Data diperoleh dari rekam medis dengan teknik purposive sampling, dianalisis dengan uji Mann-Whitney. Subjek penelitian sebanyak 68 pasien, 34 pasien ACS dengan hiperglikemia dan 34 pasien ACS tanpa hiperglikemia. Hasil penelitian ini menyatakan ada perbedaan durasi lama tinggal pasien ACS dengan dan tanpa hiperglikemia(p = 0,002) dan tidak ada perbedaan rerata mortalitas diantara keduanya.Kata kunci: Sindrom Koroner Akut, Hiperglikemia, Lama Rawat Inap, Mortalitas ABSTRACT Acute Coronary Syndrome (ACS) in recent studies has been associated with hyperglycemia at the time of admission with higher mortality rates. Hyperglycemia in patients with ACS described as an acute response from a hyperadrenergic state with an increased risk of thrombosis, so it could worsen the condition of the patient ACS during the hospital stay. Aims of this study are to know differences in length of stay and mortality in ACS patients with hyperglycemia stress and without hyperglycaemia stress. This was an analytical observational research design with cross sectional approach. The subjects were non diabetic ACS patient in RSUD X Surakarta. Data were obtained from medical record with purposive sampling technique, analyzed by Mann-Whitney test. Subjects were 68 patients, 34 patients ACS with hyperglycemia and 34 patients ACS without hyperglycemia. There is a difference in duration long of stay ACS patients with and without hyperglycemia (p = 0.002) and there is no difference in mortality.Keywords: Acute Coronary Syndrome, Hyperglycemia, Length Of Hospitalization, Mortality
PENETAPAN BATAS DARAT INDONESIA “ MALAYSIA DAN IMPLIKASINYA TERHADAP KETAHANAN WILAYAH (Studi Pada Peran Direktorat Topografi TNI AD Dalam Penetapan Batas Darat Indonesia - Malaysia Di Kecamatan Sei Menggaris Kabupaten Nunukan Provinsi Kalimantan Utara)
Authors: Susilo Hendri , Ritohardoyo Su , Zubaidi Ahmad 
Published: February 2019

This study discussed the determination of Indonesia-Malaysia land border and its implications for regional resilience (A Study of Roles of the Directorate of Topography of the Indonesian Army in the Determination of Indonesia-Malaysia Land Border in Sei Menggaris Nunukan North Kalimantan). The objectives of the study were (1) to study roles of the Directorate of Topography of the Indonesian Army in the determination of Indonesia-Malaysia land border, (2) to study the constraints faced and assessed the performance effectiveness of the Directorate of Topography of the Indonesian Army in the determination of Indonesia-Malaysia land border and (3)to trace the implication of Indonesia-Malaysia land border implemented by the Directorate of Topography of the Indonesian Army on regional resilience. This research applied the qualitative research method. Data collection methods were observations, in-depth interviews, documents and literatures review, and online data tracking.The findings indicated that roles of the Directorate of Topography of the Indonesian Army in the determination of Indonesia-Malaysia land border included border demarcation and Investigation, Refixation, and Maintenance (IRM) of Indonesia-Malaysia border. The determination of Indonesia-Malaysia land border strengthened the regional resilience of Sei Menggaris Nunukan North Kalimantan.Keywords: Land Border, Roles, Directorate of Topography of the Indonesian Army, Regional Resilience
The Hermite Hadamard Inequality on Hypercuboid
Authors: Alomari Mohammad W 
Published: February 2019

Given any a := (a1; a2,... ; an) and b := (b1; b2;... ; bn) in Rn. The n-fold convex function dened on [a; b], a; b 2 Rn with a < b is a convex function in each variable separately. In this work we prove an inequality of Hermite-Hadamard type for n-fold convex functions. Namely, we establish the inequality
Intransitive Permutation Groups with Bounded Movement Having Maximum Degree
Authors: Razzagh Behnam 
Published: February 2019

Let G be a permutation group on a set with no fixed points in and let m be a positive integer. If for each subset of the size is bounded, for , we define the movement of g as the max over all subsets of . In this paper we classified all of permutation groups on set of size 3m + 1 with 2 orbits such that has movement m . 2000 AMS classification subjects: 20B25
Management of Pneumomediastinum Associated with H1N1 Pneumonia: A Case Report
Authors: Singh Bhavna P , Shetty Gurucharan S , Vijayan Padmakumar Arayamparambil , Gopalakrishna Ullas , Chandan Garud , Santini Ario , Padegal Vivek 
Published: February 2019

Abstract
H1N1 is seen in tropical countries like India, occurring irrespective of the season. Complications of the disease are frequently encountered and there is little in the way or guidelines as to the how these should be managed. The treatment of one such complication, a recurrent pneumiomediastinum is the subject of the current paper. The management followed guidance for the treatment of a similar condition known as primary spontaneous pneumomediastinum, an uncommon condition resulting from alveolar rupture-otherwise known as the Macklin phenomenon.
Postgraduate trainee views on eHealth at a distributed medical campus.
Authors: Benjamin Sophiya , Ho Joanne , Alfonsi Jeff , Kellam Hugh 
Published: February 2019

Purpose: e-Health is a rapidly evolving field that cuts across specialties however; there is a gap in development and evaluation of training for postgraduates in residency programs. This is a multicentre, collaborative effort among faculty from the departments of Psychiatry, Geriatrics and Internal Medicine in partnership with Ontario Telehealth Network to assess the needs of postgraduate residents in ehealth and build a pilot program to address identified learning gaps.
Methodology: We conducted a needs assessment (Appendix A) through an online survey to investigate the self-perceived knowledge, gaps and barriers to eHealth of medical resident physicians at the McMaster University DeGroote School of Medicine Waterloo Regional Campus (WRC), Kitchener, Ontario, Canada
Results: All respondents identified that they would be interested in education in telehealth and all of them felt that they would have to use telehealth in their future practices. However, 83.3% did not feel confident using telemedicine in clinical practice. Based on the results of the needs assessment, we have built a pilot rotation in which postgraduate trainees can practice telehealth skills in an interdisciplinary setting.
An Invitation to Walk a Mile in Their Shoes: A Rural Immersion Experience for College Pre-medical Students
Authors: Whittington Carli P. , Crump William J. , Fricker R. Steve 
Published: February 2019

Purpose
To report the outcomes of the first 15 years of an entirely rurally-based college-level program designed to enhance rural students’ understanding of rural health and reinforce their potential affinity for rural practice.
Method
Choice of career, practice site, and evaluation results were collected from 80 program participants for the period 2003-2017. Anonymous pre- and post-survey data were analyzed using the Wilcoxon Mann-Whitney tests to compare survey results of students’ opinions of the importance of understanding traditional medical and social items when choosing a treatment option for very rural patients.
Results
The authors found no statistically significant difference between pre- and post- survey measures of opinions of traditional medical items. However, six of the nine social items showed a statistically significant increase (p <.05). The importance for a physician to understand social factors increased in post-test results for items of faith/spirituality, who prepares the patient’s meals, health beliefs held by the patient, the kind of work the patient does, how ready the patient is to make changes, and where the patient lives. Evaluations were positive and comments supported that the goals were accomplished. Of those completing each stage of training, 83% chose some health career, 58% chose medical school, 31% chose family medicine, and 66% chose primary care. Of those establishing medical practice, 50% chose a rural site.
Conclusions
Rurally-based programs may reinforce college students’ rural affinity, promoting the likelihood of completion of medical school and subsequent rural practice choice.
Funding/Support: None.
Human Subjects: This study was determined exempt by the Baptist Health Madisonville Institutional Review Board.
Conflicts of Interest: None
(Z)-N'-(1H-Benzo[d]imidazol-2-Yl)-Arylimidamide Adducts of 2-Aminobenzimidazole and Aromatic Nitriles: Structural and Spectroscopic Proof of Regiochemical and Stereochemical Outcomes
Authors: Stoermer Martin , Egan Simon , Forsyth Craig M. , Moloney Gerard 
Published: February 2019

The selection of a core scaffold or template is of enormous importance in medicinal chemistry. Benzimidazoles are a recurring fragment in medicinal chemistry, and the 2-amino derivative is a versatile example in lead generation. Alkylated and acylated examples abound, however, alternative linkage chemistries leading do more diverse structures are needed. Here we discuss the regiochemistry of nucleophilic addition of 2-aminobenzimidazole to nitriles, leading to imidamide (amidine) adducts. Additionally, we use extensive NMR analysis and ultimately X-ray crystallography to demonstrate both the regiochemistry and stereochemistry of the addition products, arising from derivatisation of the exocylic 2-amino group.
FUNGSIONALISASI HUKUM KEKAYAAN INTELEKTUAL DALAM KOMERSIALISASI KEKAYAAN INTELEKTUAL OLEH INDUSTRI DAN USAHA KECIL MENENGAH DI PULAU LOMBOK NTB
Authors: BF Ari Rahmad Hakim , Kaharudin Kaharudin 
Published: February 2019

Fungsi hukum dalam komersialisasi dan eksploitasi invensi dan kreasi kekayaan intelektual yang dihasilkan oleh Industri kecil menengah merupakan bagaian dari upaya yang dapat dilakukan agar industri kecil menengah memperoleh kepastian dan perlindungan hukum terhadap penggunaan atau pemanfaatan invensi dan kreasi yang dihasilkannya. Untuk mendapatkan perlindungan hukum agar tidak diklaim dan untuk dapat menuntut pihak lain yang menggunakan tanpa ijin, maka industri kecil menengah yang menghasilkan invensi dan kreasi tertentu sesuai dengan peraturan yang berlaku di bidang kekayaan intelektual di Indonesia maka wajib hukumnya untuk didaftarkan (prinsif konstitutif), kemudian setelah dilakukan pendaftaran Hak Kekayaan Intelektual tersebut dalam pengekploitasian dan pengkomersialisasiannya agar Industri kecil menengah aman, maka dapat dilakukan dengan mekanisme Hukum Jual beli, lisensi (ijin pemanfaatan), Joint venture (usaha patungan) dan melalui mekanisme franchising (waralaba).
PERSEPSI MASYARAKAT TENTANG PENTINGNYA AKTA PPAT DALAM PERALIHAN HAK ATAS TANAH DI KECAMATAN WERA.
Authors: Arba Arba , Umar Muhammad , Sahruddin Sahruddin 
Published: February 2019

Peraturan perundang-undangan memerintahkan kepada semua orang yang melakukan peralihan hak atas tanah wajib didaftar. Pendaftaran peralihan hak ini dilakukan apabila dibuktikan dengan akta peralihan hak yang dibuat dihadapan dan ditanda tangani oleh PPAT. Penelitian ini bertujuan untuk menganalisis penerapan peraturan perundang-undangan di bidang peralihan hak atas tanah; Untuk memahami persepsi masyarakat desa tentang pentingnya akta PPAT dalam transaksi peralihan hak atas tanah; dan Untuk menganlisis faktor-faktor yang mempengaruhi pelaksanaan pembuatan akta PPAT dalam peralihan atas tanah di masyarakat kecamatan Wera. Penelitian ini adalah penelitian hukum Empiris, maka metode pendekatan yang digunakan adalah pendekatan hukum empiris, yaitu: pendekatan konsep, stuta, dan sosiologis. Hasil penelitian menunjukan bahwa penerapan ketentuan peraturan perundang-undangan di bidang peralihan hak atas tanah, khususnya pembuatan akta PPAT dibidang peralihan hak atas tanah di kecamatan Wera sudah terlaksana dengan baik; Persepsi masyarakat desa tentang pentingnya akta PPAT dalam transaksi peralihan hak atas tanah sudah sangat baik, namun pelaksanaannya masih mengalami hambatan-hambatan disebabkan dua faktor utama, yaitu faktor masyarakat itu sendiri, yakni lingkungan di mana hukum itu berlaku dan diterapkan; dan faktor kebudayaan, yakni sebagai hasil karya, cipta, dan rasa yang didasarkan pada karsa manusia di dalam pergaulan hidup. Kedua faktor ini sekarang sangat dinamis karena dipengaruhi oleh kemajuan ilmu pengetahuan, telekomunikasi dan transportasi. Faktor-faktor ini bukan ditiadakan tetapi harus dikelola dengan baik.
IUCD;
Authors: Khudija Aysha , Rabbani Attia , Zafar Dar Huma 
Published: February 2019

Objectives: To determine the frequency of expulsion of post PPIUCD after spontaneous vaginal delivery. Study Design: Cross sectional study. Setting: Department of Obstetrics & Gynaecology Unit-II, Lady Willingdon Hospital, Lahore. Period: October 2013 to October 2014. Methodology: In this study the pregnant females delivering vaginally at any age of gestation were included. The cases were selected irrespective of gravida, parity and having age range of 18 years or more. The cases undergoing any instrumentation or surgical intervention were excluded. Then these cases were followed for 6 weeks postpartum and X ray was done to confirm the position of IUCD and absence of the radio opaque shadow reveal its expulsion. Results: In this study 150 pregnant females were selected. The mean age of the subjects was 29.13±4.46 years. PPIUCD expulsion was seen in 11 (7.33%) of cases. PPIUCD expulsion was more commonly seen in age group more than 30 years affecting 7 (8.33%) of cases with p=0.24. PPIUCD was also more often seen in cases with multiparous women where it was observed in 08 (7.55%) cases with p= 0.78. Conclusion: Expulsion of PPIUCD is not uncommon and is more common in cases with age more than 30 years and multiparous women.