bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minimum Muscular Fitness of Secondary Level Students
Authors: Bhatt Mahesh Datt , Datt Tara 
Published: September 2019

This paper deals with the minimum muscular fitness of secondary level students of Birendranagar Municipality of Surkhet of Nepal. Two hundred fifty five secondary level students were tested with Kraus-Weber tests for their minimum muscular fitness. The age of the students was thirteen to eighteen years. The results revealed that 71.03 percent boys and 62.73 percent girls had minimum muscular fitness. Among the tested subjects 35.94 percent Bhraman-Chhetri, 25.86 percent Janajati and31.89 percent Dalit did not have the minimum muscular fitness. Weakness plays a significant role than the flexibility not to gain minimum muscular fitness to the subjects.
Approach formation for the development of compounding preparation monographs
Authors: Zdoryk O. A. , Georgiyants V. А. , Gryzodub O. I. 
Published: September 2019

Questions of standardization of compounding preparations are quite relevant both in Ukraine and abroad. Today the general monograph «5.N.1. Extemporaneous preparations» of the State Pharmacopoeia of Ukraine is revised by the staff of the Ukrainian scientific pharmacopoeial center for quality of medicines and the National University of Pharmacy, also the additional articles for compounding preparations are developed.
The aim of this work is substantiation of the structure and format of the compounding preparation monographs for introduction to the national part of the State Pharmacopoeia of Ukraine.
The researches were performed using data of the world pharmacopoeias and national formularies, as well as the experience of standardization of compounding preparations in Ukraine and the USSR.
In the study, general statements for the development of compounding preparations monographs were formed and its structure was discussed. The requirements and examples are described for each item of the monograph. For monographs of the State Pharmacopoeia of Ukraine such structure were offered: name, composition, lists the acceptable range of labeled amount of main ingredient, technology of preparation, reference for the general monographs, properties, identification, tests, assay, expiration date, labeling, storage, references to the regulatory documents, and indications. For systematization of the monographs’ development procedure the work order was composed. The procedure of monographs development includes selection of the object, study of literature data, and study of the basic stages of the compounding process, evaluation of quality control methods, experimental researches, and conclusion about conformity with the requirements, quality control method validation protocols, stability studies, and development of the monograph’s draft.
As the result of research the structure, format, stages and order of the development of compounding preparations’ monographs for introduction to the State Pharmacopoeia of Ukraine were proposed.
Synthesis, physical-chemical and biological properties of 8-aminoderivatives of 7-alkyl-3-methylxanthines
Authors: Romanenko M. I. , Nazarenko M. V. , Ivanchenko D. G. , Kamyshny O. M. , Polishchuk N. M. 
Published: September 2019

The search for new high-performance antimicrobial compounds remains one of the most important tasks of modern pharmaceutical chemistry, despite the wide range of modern natural, synthetic and semi-synthetic drugs for the treatment of infectious diseases.This is especially true for the naturally occurring compounds, new non-toxic and effective drugs can be created by their chemical modification for the treatment of various infectious pathologies. Recent researches in this area point to significant prospect of new synthetic derivatives of xanthine.
The aim of this work is to develop simple laboratory methods for synthesizing 8-aminoderivatives of 7-alkyl-3-methylxanthines and to study their physical and chemical peculiarities and antimicrobial properties.
The meltingpoint has been determined with the help of an open capillary method with TAP device (M). Elemental analysis has been performed with the help of the instrument ElementarVario L cube, NMR-spectra have been taken on a spectrometer Bruker SF-400 (operating frequency of 400 MHz, solvent DMSO-d6, internal standard – TMS). These data correspond to the calculated elemental analysis.
For the initial screening study of the newly-synthesized substances benchmark testing-cultures of both gram-positive and gram-negative bacteria have been used, which belong to clinically significant groups of infections agents which are differing by their morpho-physiological properties.
Through the reaction of 7-alkyl-3-methylxanthines with primary and secondary amines in water, water-ethanol, water-dioxane or cellosolve environment a range of 8-aminoderivativeshas been obtained which was not described earlier.
Developing accessible laboratory methods to synthesize new 8-aminoderivatives of 7-alkyl-3-methylxanthines, which are potential bioactive compounds. Studying NMR-spectral characteristics of the obtained substances.
Initial screening research of antimicrobial activity of the synthesized compounds has shown that 8-aminoxanthines (4, 6–12) can be used in medical practice as antistaphylococcal drugs, and 3-methyl-8-(4-methylpiperidine-1-yl)-7-n-propilxanthine (5)– antifungal agentafter additional studies.
Rationale of method of analysis of evidence-based data on the pharmacological activity of succinic acid and its combinations drugs
Authors: Leleka M. V. , Zalis′ka O. M. 
Published: September 2019

Succinic acid as endogenous metabolite has a wide range of applications in medical practice in Ukraine and abroad. We research a new medicines, based on succinic acid, ascorbic acid and rutin for the prevention and treatment of influenza. Analysis of the data evidence-based medicine necessary for the implementation of quality assessment study feasibility of adding succinic acid in the various dosage forms and determine their pharmacological activity.
It was studied international databases and registers of clinical trials MEDLINE®, EMBASE®, Scopus, Cochrane Library for the period from 1966 to June 2015. In the search for key phrases search engine electronic library «The Cochrane Library» found 872 913 publications, including 71 in the section «Trials». Of these, only 23 were devoted to review the results of clinical trials of medications that contain in their composition succinic acid.
In the analysis of papers revealed that all 12 Trials of the search engine PubMed are present in search results «The Cochrane Library». Therefore, for further analysis we selected directory search results Trials «The Cochrane Library» and 3 Review of retrieval system PubMed.
We analyzed Trials in terms of pharmacological activity and dynamics of publications. For pharmacological properties and relevance RCTs grouped as follows: antihypoxic action confirm 7 RCT (2003–2013 years), improve of iron absorption in the gastrointestinal tract – 6 RCT (1966–1974 years), hepatoprotective – 4 RCT (2013–2014 years). One RCT has effectiveness succinic acid for use in gastroenterology (in combination with omeprazole, 2012), depression (2013), the transplant (1993) during menopause (2008), renal failure (2013) for fever during surgery (2007). We can call such medicines containing succinic acid and have proven clinical efficacy: Remaksol, Tsytoflavin, Vecam (Omeprazole + succinic acid). We analyzed the Review of reviews of retrieval system PubMed. Analysis reviews MedLine (Review) opens new prospects for the use of succinic acid in the treatment of hypoxia and viral hepatitis. The results of clinical trials confirm the feasibility of developing new drugs with succinic acid.
We conducted a review of evidence data about the inclusion of succinic acid in the various dosage forms. Succinic acid is the part of the drugs with different pharmacological effect. The results of clinical trials confirm the feasibility of developing of new drugs with succinic acid.
Safety and efficacy of ultrasound guided percutaneous needle aspiration of liver abscess
Authors: Salahuddin G , Parvin Sadika , Mollick Md Kutub Uddin , Hossain Syed Mozammel 
Published: September 2019

Background: Liver abscesses, both amoebic and pyogenic, continue to be an important cause of morbidity and mortality in tropical country. Traditionally for many years they were treated with antimicrobial alone, blind percutaneous aspiration or surgical exploration. This conception gradually changes into guided percutaneous aspiration or drainage with development of advanced diagnostic imaging modality.
Objectives: To evaluate the safety and efficacy of management of liver abscess by Ultrasound (US) guided percutaneous needle aspiration.
Methods: From August 2009 to July 2018 a total 380 patients with liver abscess were referred to the department of radiology and imaging for US guided percutancous aspiration. All patients were evaluated clinically and by USG. Aspiration of the abscess was carried out under strict aseptic precaution.
Results: A total of 380 patients with liver abscess were successfully treated, consisting of 338 males and 42 females, male female ratio 8:1. The age ranges from 11 to 80 years. Majority (78%) had single abscess and 22% had two or more. Most of the abscess are located in the right lobe of liver (79%). Single needle aspiration were needed in 30% of patient, second aspiration were needed in 38% of patients and third aspiration in 32% of patients. Average aspiration per patient was 2.02. The amount of aspirated pus ranged from 250 to 2450 ml.
Conclusion: Ultrasound guided percutaneous needle aspiration of liver abscess is a safe and successful therapeutic approach in the treatment of liver abscess whether pyogenic or amoebic.
Bang Med J (Khulna) 2018; 51 : 3-6
O MAGISTRADO PORTUGUÊS JOAQUIM THEOTÔNIO SEGURADO E A CRIAÇÃO DA PROVÍNCIA DE SÃO JOÃO DAS DUAS BARRAS NO CONTEXTO DA INDEPENDÊNCIA DO BRASIL
Authors: Flores Kátia Maia 
Published: September 2019

A história da criação do estado do Tocantins pela Constituição, de 1988, traz à luz a luta separatista entre norte e sul de Goiás, cujos marcos revelam vários movimentos conduzidos por lideranças populares e políticas, em diferentes épocas. Dentre as lideranças separatistas, destaca-se a figura emblemática do magistrado português, o desembargador Joaquim Theotônio Segurado, ouvidor de Goiás (1804-1821), e o movimento que culminou com a criação da província de São João das Duas Barras entre os anos 1821-1822. Segurado foi ouvidor geral de Goiás e primeiro ouvidor da comarca do norte, onde, no exercício do cargo e valendo-se das possibilidades, construiu uma rede de articulações políticas, administrativas, econômicas e sociais que extrapolavam em muito o campo de atuação dos magistrados, cujas carreiras eram prescritas no interior do aparelho judicial ultramarino português. Foi com esse campo de poder conquistado nos muitos anos no norte que se alçou como uma das principais lideranças do movimento separatista do norte goiano, onde advogava a separação de Goiás e sua autonomia, dentro de uma nova geopolítica encabeçada por Maranhão e Pará. Sua atuação como ouvidor em Goiás extrapolou em muito o prescrito para o exercício do cargo dentro dos procedimentos jurídico-administrativos desenhados pela legislação ibérica. O presente artigo é parte de uma pesquisa de maior envergadura, realizada sobre o desembargador Joaquim Theotônio Segurado em arquivos do Brasil e de Portugal, no intuito de reconstruir os percursos da carreira jurídica do magistrado.
“Você precisa falar português com seu filho”: Desafios para o processo de inclusão de crianças imigrantes em escolas do Rio de Janeiro
Authors: Assumpção Adriana Maria , Aguiar Gabriela De Azevedo 
Published: September 2019

O presente trabalho apresenta uma reflexão teórica sobre a inclusão de crianças imigrantes no contexto escolar brasileiro, particularmente, em escolas do Rio de Janeiro. Abordamos a legislação pertinente e as práticas de espaços de educação formal, a partir das narrativas de crianças e suas respectivas mães. Nosso interesse é suscitar reflexões para a compreensão da questão do direito das crianças imigrantes à educação, considerando acesso e inclusão, como pontos fundamentais nesta discussão
Branch Retinal Vein Occlusion with Vitreous Hemorrhage Identified During Intraoperative Vitrectomy
Authors: Sukmono Nafila Mahida , Amin Ramzi 
Published: September 2019

Introduction Retinal vein occlusion is the largest group of retinal blood vessels after diabetic retinopathy. Occlusion occurring in the retinal vein is divided into central retinal vein occlusion (CRVO) occlusion and branch retinal vein occlusion (BRVO) occlusion. The Beijing Eye Study, reported a higher incidence of BRVO than CRVO, where 10-year incidents for BRVO were 1.6 per 100 subjects, and CRVO was only 0.3% 100 subjects.1 To report a case of Branch Retinal Vein Occlusion with vitreous hemorrhage identified during intraoperative vitrectomy
Method: A 49-year-old woman with a history of 15 years of hypertension had right eye vision complaints, increasingly blurred since last 2 months. The right eye visual acuity 2/60 cannot be corrected and left eye 6/30 cannot be corrected. The posterior segment on right eye is difficult to assess. USG B-Scan right eye found vitreous echospike appearance of vitreous bleeding. We manage with vitrectomy and during intraoperative we identified bleeding and ghost vessel in superotemporal area. Bleeding in the superotemporal quadrant is done by photocoagulation laser action.
Results: First day postoperative there was increased in visual acuity to 6/60 with a posterior segment that could be assessed, obtained tortous blood vessels, slight bleeding and ghost vessel in the superotemporal area with laser injury.
Conclusion: In this case report, patients with BRVO with complications of vitreous hemorrhage performed vitrectomy with additional endolaser in the ischemic area. The result of this action of visual acuity improvement in patient.
PEMANFAATAN PEKARANGAN MENJADI KEBUN SAYUR PRODUKTIF DI DAERAH PESISIR DI KECAMATAN WARA TIMUR
Authors: Yasin Sitti Maryam , Kasim Niken Nur 
Published: September 2019

Salah satu kecamatan pesisir laut di Kota Palopo adalah Kecamatan Wara Timur, Wilayahnya sebagian tambak dan masyarakat tinggal di rumah-rumah panggung yang dibawahnya terdapat air yang kadang pasang surut. Sebagian pekarangan cukup luas namun kondisi tanah yang berbatu dan berpasir tidak mampu dijadikan lahan yang subur, kondisi tanah yang salin tidak memungkinkan melakukan budidaya tanaman. Oleh karena itu, pemerintah dan perangkat desa setempat, warga, serta kaum ibu rumah tangga yang tergabung dalam kelompok Wanita Tani Mattirosompe dan kelompok wanita tani Al, abrar di Kecamatan Wara Timur memikirkan program untuk memanfaatkan lahan pekarangan rumah agar lebih produktif untuk ditanami berbagai jenis sayuran. Â Berdasarkan hal tersebut maka masyarakat perlu diberi pengetahuan dan keterampilan membudidayakan tanaman secaraÂ vertikultur, yaitu model pertanaman vertikal dengan pot atau pipa, baik dengan menggunakan media tanah/konvensional atau dengan teknologi sistimÂ hidroponik yaitu menanam tanpa menggunakan tanahTujuan yang ingin dicapai dari kegiatan ini adalah memberikan pengetahuan dan keterampilan bagi masyarakat pesisir tentang budidaya tanaman secara vertikultur dan hidroponik. Kelurahan Ponjalae dapat memproduksi sendiri berbagai jenis sayuran dari halaman pekarangan rumahnya, minimal untuk kebutuhan konsumsi keluarga sendiri, atau minimal mengurangi pengeluaran rumah tangga warga nelayan untuk membeli sayuran. Â Metode yang akan digunakan dalam budidaya tanaman secara vertikultur yang secara konvensional (menggunakan media tanah) dan sistem teknologi hidroponik dengan penyiraman dan hara otomatis.Â Jenis-jenis tanaman yang akan ditanam adalah kelompok tanaman hortikultura yaitu tanaman sayuran dan buah. Sebelum membudidayakan tanaman secara vertikultur dan hidroponik terlebih dahulu masyarakat akan diberi pelatihan agar masyarakat dapat melakukan secara baik dan benar sehingga tanaman dapat tumbuh dan berkembang dengan baik.
VIOLÊNCIA CONTRA ADOLESCENTES E JOVENS HOMOSSEXUAIS E OS IMPACTOS NA SAÚDE
Authors: Braga Iara Falleiros , Natarelli Taison Regis Penariol , Farias Marilurdes Silva , Silva Marta Angélica Iossi 
Published: September 2019

Realizou-se uma revisão integrativa com o objetivo de investigar as evidências disponíveis na literatura sobre a violência contra adolescentes e jovens homossexuais. Foram consultadas as bases de dados PubMed, LILACS, CINAHL e Web of Science considerando as publicações de 2010 a 2015. Foram selecionados 14 artigos a partir dos quais foram extraídas três unidades temáticas: tipos de violência e seus contextos; Impactos da violência na saúde e Sexualidade e educação. Os resultados evidenciaram que a violência tem potencializado a vulnerabilidade a que os adolescentes e jovens estão expostos. A heteronormatividade tem legitimado a produção e a manutenção de diversas situações de violência, em diversos contextos de convivência desses adolescentes e jovens, com sérios impactos em suas saúdes. Ressalta-se a necessidade de futuras pesquisas acerca da violência sofrida e vivenciada no cotidiano dessa população, buscando contribuir para políticas públicas e de formação profissional, especialmente nas áreas da saúde e da educação, que se pautem na proteção integral, na equidade, nos direitos humanos, no respeito à diversidade sexual, visando a ressignificação da normalidade expressa pela sexualidade enquanto um dispositivo de poder e controle, e o seu padrão heteronormativo.
Keck/OSIRIS IFU Detection of a z ∼ 3 Damped Lyα Host Galaxy∗
Authors: Christenson Holly M. , Jorgenson Regina A. 
Published: September 2019

Abstract
We present Keck/OSIRIS infrared IFU observations of the z = 3.153 sub-DLA DLA2233+131, previously detected in absorption to a background quasar and studied with single-slit spectroscopy and Potsdam Multi Aperture Spectrophotometer integral field spectroscopy (IFU). We used the Laser Guide Star Adaptive Optics and OSIRIS IFU to reduce the point-spread function of the background quasar to FWHM ∼ 0.″15 and marginally resolve extended, foreground DLA emission. We detect

emission with a flux

erg s−1 cm−2, as well as unresolved

and Hβλ4861 emission. Using a composite spectrum over the emission region, we measure dynamical mass

M
⊙. We made several estimates of star formation rate (SFR) using

and Hβλ4861 emission, and measured a SFR of ∼7.1 − 13.6 M
⊙ yr−1. We map

and Hβλ4861 emission and the corresponding velocity fields to search for signs of kinematic structure. These maps allow for a more detailed kinematic analysis than previously possible for this galaxy. While some regions show slightly red and blueshifted emission indicative of potential edge-on disk rotation, the data are insufficient to support this interpretation.
Dynamical Histories of the Crater II and Hercules Dwarf Galaxies
Authors: Fu Sal Wanying , Simon Joshua D. , Jara Alex G. Alarcón 
Published: September 2019

Abstract
We investigate the possibility that the dwarf galaxies Crater II and Hercules have previously been tidally stripped by the Milky Way. We present Magellan/IMACS spectra of candidate member stars in both objects. We identify 37 members of Crater II, 25 of which have velocity measurements in the literature, and we classify three stars within that subset as possible binaries. We find that including or removing these binary candidates does not change the derived velocity dispersion of Crater II. Excluding the binary candidates, we measure a velocity dispersion of

km s−1, corresponding to

M
⊙/L
⊙. We measure a mean metallicity of

, with a dispersion of

. Our velocity dispersion and metallicity measurements agree with previous measurements for Crater II, and confirm that the galaxy resides in a kinematically cold dark-matter halo. We also search for spectroscopic members stripped from Hercules in the possible extratidal stellar overdensities surrounding the dwarf. For both galaxies, we calculate proper motions using Gaia DR2 astrometry, and use their full 6D phase space information to evaluate the probability that their orbits approach sufficiently close to the Milky Way to experience tidal stripping. Given the available kinematic data, we find a probability of ∼40% that Hercules has suffered tidal stripping. The proper motion of Crater II makes it almost certain to be stripped.
Slitless Solar Imaging Spectroscopy
Authors: Davila Joseph M. , Oktem Figen S. , Kamalabadi Farzad 
Published: September 2019

Abstract
Spectrometers provide our most detailed diagnostics of the solar coronal plasma, and spectral data is routinely used to measure the temperature, density, and flow velocity in coronal features. However, spectrographs suffer from a limited instantaneous field of view (IFOV). Conversely, imaging instruments can provide a relatively large IFOV, but extreme-ultraviolet (EUV) multilayer imaging offers very limited spectral resolution. In this paper, we suggest an instrument concept that combines the large IFOV of an imager with the diagnostic capability of a spectrograph, develop a new parametric model to describe the instrument, and evaluate a new method for “deconvolving” the data from such an instrument. To demonstrate the operating principle of this new slitless spectroscopy instrument, actual spectroscopic raster data from the Hinode/EUV Imaging Spectrometer (EIS) spectrometer is used. We assume that observations in multiple spectral orders are obtained, and then use a new inverse problem method to infer the spectral properties. Unlike previous methods, physical constraints and regularization derived from prior knowledge can be naturally incorporated as part of the solution process. We find that the fidelity of the solution is vastly improved compared to previous methods. The errors are typically only a few km s−1 over a large IFOV, with a width of a few hundred pixels and an arbitrarily large height. These errors are not much larger than the errors in current slit spectroscopic instruments with limited IFOV. A further benefit is that the performance of candidate instruments can be optimized for specific scientific objectives. We demonstrate this by deriving optimum values for the spectral dispersion and signal-to-noise ratio.