bluuebunny/crossref_metadata_2025_split huggingface dataset:
NADI SHODHANA PRANAYAMA AND ITS IMPACT ON PARAMETERS OF CARDIOVASCULAR, PULMONARY, AND BRAIN FUNCTIONS
Authors: Vaksh Dr. Shreyasi , Pandey Dr. Mukesh 
Published: July 2019

Background: Practice of pranayama has been recognized to control cardiac autonomic status with an improvement in cardio-respiratory functions.
Objective: To determine impact of Nadi-shodana pranayama practice for 20 minutes on heart rate, systolic and diastolic blood pressure, peak expiratory flow rate.
Methods: Ninety normal healthy subjects aged between 17-20 years of first year MBBS course volunteered for this study out of total 150. Among them 40 were females and 50 were males. They did not have any previous training in Pranayama. All the selected physiological parameters were measured before and after performing ‘Nadi-shodhana Pranayama’. Epi-info 7 was used for analysis.
Results: Following nadi-shodhana pranayama a significant decline in basal heart rate and systolic blood pressure was observed. Peak expiratory flow rate was significantly improved (P<0.01). No significant changes in respiratory and other cardiovascular parameters were seen.
Conclusion: Nadi-shodhana Pranayama swiftly alters cardiopulmonary response. Further studies on a larger sample size need to illustrate the underlying mechanisms involved in this alteration.
Keywords: Nadi-shodhana pranayama, heart rate, blood pressure, peak expiratory flow rate.
COMPARISON OF ESMOLOL, LABETALOL AND LIGNOCAINE FOR ATTENUATION OF SYMPATHOMIMETIC RESPONSES TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION
Authors: Kirankumar Dr. H. 
Published: July 2019

INTRODUCTION: In some individual’s suffering from hypertension, coronary artery disease, cerebrovascular disease, myocardial infarction and thyrotoxicosis, these hemodynamic stress responses can turn into life-threatening conditions like left ventricular failure, myocardial ischemia, cerebral hemorrhage, and ruptured cerebral aneurysm. Different drugs like lidocaine, vasodilator agents inhibiting sympathoadrenal response, α-and β-adrenergic blockers, and opioids can be administered prior to tracheal intubation to prevent hemodynamic responses. But higher dose of lignocaine may lead to hypotension, bradycardia, and hypoxia in patients. Due to various effect of these drugs on hemodynamic changes in patients this study was carried out to evaluate the effects of IV esmolol, lignocaine, and labetalol for attenuation of hemodynamic response to laryngoscopy and intubation.
MATERIAL AND METHODS: A total of 90 consecutive patients were included in the study and were grouped in to, lignocaine group, labetalol and esmolol group containing 30 patients each. Age group 21–65 years of either sex or American Society of Anesthesiologists (ASA) Grade I or II scheduled for various general surgical procedures under endotracheal anesthesia were included in this study. Patients excluded were pregnant and lactating women, morbid obesity, and hypertension.
RESULTS: Mean Age in Group 1, group2 and group 3 was 40.38 ± 7.25, 43.8 ± 9.24 and 42.56 ± 8.71 respectively while weight was 62.41 ± 7.32, 63.63 ± 8.11 and 60.74 ± 6.92 respectively. There were 17 male and 13 female in group 1, 19 male and 11 female in group 2 and 16 male and 14 female in group 3. Attenuation of blood pressure was more in labetalol group. Reduction of heart rate in labetalol group was significant. It is seen that Labetalol was more effective at attenuation of diastolic blood pressure among all drugs. Mean arterial pressure was not much reduced lignocaine and esmolol group as compared to labetalol.
CONCLUSION: Haemodynamic alterations are usually observed during laryngoscopy and endotracheal intubation. In our study it was found that as labetalol is a safe and effective drug, for attenuation of sympathomimetic response.
RETROSPECTIVE ANALYSIS OF MULTIPLE MYELOMA PATIENTS IN A TERTIARY CARE CENTRE OF UTTARAKHAND
Authors: Shukla Sushil Kumar , Shrivastava Vikas , Kala Mansi , Das Kunal , Kusum Anuradha 
Published: July 2019

Introduction: Multiple myeloma (MM) is a hemato-lymphoid malignancy of B-cell type. It occurs due to the accumulation of malignant monoclonal plasma cells. The exact incidence of MM in India is not well-known. The current study presented the clinical characteristics, radiological findings and laboratory findings of MM patients who were initially treated at the tertiary care centre, Dehradun, Uttarakhand (India).
Material and methods: Retrospective analysis of the medical records of 123 consecutive patients with MM who were initially presented to Hemato-Oncology department during the period from January 2014 to December 2018. Peripheral blood finding, bone marrow diagnosis, flow-cytometry analysis, serum protein and immunofixation electrophoresis finding, biochemical parameter, histo-pathological and cytological diagnosis, if any, urine examination finding and radiological examination of cases shall be compiled and tabulated. Diagnosis of symptomatic multiple myeloma was done based on The International Myeloma Working Group criteria for the diagnosis of MM.
Result: The study included 123 cases of multiple myeloma with male: female ratio of 2:1, mean age of 59.88 ±11.08 years and range of 32-87 years. The back pain (n=106, 86.2%) was the common presenting complaint followed by inability to walk (n=90,73.2%). CT scan and/or MRI scan finding of MM patients, the lytic lesion was found in 107 patients (87%) and was found significant with its correlation with ISS/DS plus staging system (pvalue 0.013). The most location was dorso-lumbar spine (n=72, 67.28%) followed by skull (n=37, 34.58%) and ribs (n=19, 17.75%). Hemoglobin (Hb) analysis showed 92.7 % (n=114) cases were anemic with mostly had normocytic (n=95,77.2%). 62.6%(n=77) of cases showed rouleaux formation while 23.57% (n=29) cases were circulating plasmacytoid lymphocytes or plasma cells. The raised ESR values was found in 89.33% (n=67) of cases. Diagnosis of cases shows 99.2% (n=122) of cases diagnosed as secretory MM while 1 (0.8%) case diagnosed as non-secretory MM.
Conclusion: MM is a disease with a inconsistent clinical presentation with multiple system involvement. Younger age of disease onset is some noteworthy features of myeloma in Uttarakhand state of India. Bony pain associated with generalized weakness is the commonest presentation, normocytic normochromic anemia with rouleaux formation, raised ESR, raised total protein with hypoalbuminemia, hypercalcemia, presence of M band and presence of >10% plasma cell in bone marrow is clue to diagnosis in MM cases .
Keywords: Multiple Myeloma, Uttrakhand, Hemato-lymphoid malignancy
The Dynamics of Education on the Development of an Intellectual Citizenry in Africa
Authors: Dzvimbo Munyaradzi A. 
Published: July 2019

This article explores the importance of education and schooling precisely, as the catalyst for the development and transformation of citizens within, the African context. Historically, intellectual and citizenship education has always been seen as a western concept within the African continent. Hence, this exacerbated the myopic view that intellectual education is new as its approach in schools is often western oriented. Drawing from post-colonial theory, this study opines that though education and learning in particular have played a pivotal role in the enhancement and transformation of citizens in Africa as a whole during the post-independence era, citizenship education is not a new concept. Further, I expound and interrogate the African governments’ efforts and initiatives in fostering citizenship through learning. More so, this study points out that if we do move beyond any labelling essentialities, intellectualism has always been part and parcel of the nucleus of education among these nations and schools have also served as catalyst of social change. This is clearly reflected in various tasks and projects found in educational policies and frameworks which include enhancing the provision and access to education, language policies, indigenous knowledge systems and the indigenisation of the school curriculum to enable it to be relevant to the current national ideals and vision. Conclusively, these programmes and initiatives were obviously implemented towards citizenship development aimed at empowering pupils with specific kind of education ideal for intellectual and national development within the countries of the Global South. Thus, the paper opines that the teaching of new learning areas through heritage studies in secondary schools, national and strategic studies in tertiary institutions should further be reconceptualised to reflect the local context and their ways of understanding and deconstructing the colonial narratives and mind set.
From Missionary Translation to Local Theological Inquiry: A Narrative History of the Lisu Bible
Authors: Arrington Aminta 
Published: July 2019

The Lisu are a largely Christian minority group in south-west China who, as an oral culture, express their faith more through a set of Christian practices done as a group and less through bible reading as individuals. Even so, the Lisu practice of Christianity specifically, and Lisu culture more generally, was profoundly impacted by the written scriptures. During the initial evangelisation of the Lisu by the China Inland Mission, missionaries created a written script for the Lisu language. Churches were constructed and organised, which led to the creation of bible schools and the work of bible translation. In the waves of government persecution after 1949, Lisu New Testaments were hidden away up in the mountains by Lisu Christians. After 1980, the Lisu reclaimed their faith by listening to the village elders tell the Old Story around the fires and reopening the churches that had been closed for twenty-two years. And they reclaimed their bible by retrieving the scriptures from the hills and copying them in the evening by the light of a torch. The Lisu bible has its own narrative history, consisting of script creating, translating, migrating, and copying by hand. At times it was largely influenced by the mission narrative, but at other times, the Lisu bible itself was the lead character in the story. Ultimately, the story of the Lisu bible reflects the Lisu Christian story of moving from missionary beginnings to local leadership and, ultimately, to local theological inquiry.
Fundamentals of the Warburg Effect in Cancer
Authors: Zhang Pi Xian , Xing Ya Qi , Niu Yong Dong 
Published: July 2019

Abstract:
As the fundamental energy unit of most cells, the ATP generated from glucose is vital to maintain biological processes such as the synthesis of proteins and nucleic acids. However, a common feature of cancer cells is an altered metabolism with increased glucose uptake and the fermentation of glucose to lactate even in the presence of normal mitochondria. This phenomenon is known as the ‘Warburg effect’ (now termed aerobic glycolysis). One simple explanation for this effect is that it permits cells to more easily produce energy to support rapid growth. It can also help to meet the biosynthetic requirements for pyruvate as a major building block. As a well-known metabolic hallmark of cancer cells, the role of the Warburg effect in oncology is a newly-emerging area of growing interest. In this perspective, we provide some new understanding of these mechanisms based on recent progress in research on cancer metabolism. The better understanding of these mechanisms will support the development of new therapeutic strategies that take into account tumor nutrition and energy metabolism.
Penerapan Metode Pembelajaran Kooperatif Tipe Think-Pair-Share Untuk Meningkatkan Hasil Belajar Siswa Kelas XI MIA.2 SMA Negeri 3 Model Takalar (Studi pada Materi Pokok Larutan Asam-Basa)
Authors: Hardyanti Arki Andi Khaerunnisa , Auliah Army , Dini Iwan 
Published: July 2019

ABSTRAKPenelitian tindakan kelas (PTK) ini bertujuan untuk mengetahui cara menerapkan langkah-langkah metode pembelajaran kooperatif tipe TPS sehingga dapat meningkatkan hasil belajar siswa kelas XI MIA.2 SMA Negeri 3 Model Takalar. Empat tahapan PTK, yaitu (1) perencanaan, (2) pelaksanaan, (3) pengamatan, dan (4) refleksi. Penelitian ini dilakukan sebanyak dua siklus. Data hasil penelitian menunjukkan bahwa metode pembelajaran tipe TPS dapat meningkatkan hasil belajar siswa Kelas XI MIA.2 SMA Negeri 3 Model Takalar yang terdiri dari 7 langkah yaitu: (1) menjelaskan tujuan pembelajaran dan mengaitkan materi pembelajaran dengan materi sebelumnya; (2) memberikan masalah kepada siswa secara tertulis yang diselesaikan secara individual dengan memberikan Time Of Think selama 15 menit; (3) mengelompokkan siswa secara berkelompok secara sejajar yang kemudian mendiskusikan hasil pemikiran individualnya secara silang; (4) membagikan hasil diskusi kelompok kepada kelompok lain dengan mempresentasekan secara singkat; (5) memberikan tes kepada siswa berupa soal essay yang dikerjakan oleh siswa seara individual untuk menguji kemampuan yang dimilikinya; (6) memberikan reward dalam bentuk pujian kepada setiap siswa yang memiliki nilai tertinggi; dan (7) meminta siswa untuk menyimpulkan hasil pembelajaran sesuai dengan tujuan pembelajaran. Hasil belajar siswa siklus I yaitu 62.13% tidak mencapai ketuntasan. Hasil belajar siswa siklus II yaitu 87.06% mencapai ketuntasan.Kata kunci: TPS, Hasil belajar, Asam basa ABSTRACTThis classroom action research aims to know how to apply the cooperative learning method of TPS type to enhance the student’s achievement of the class XI MIA.2 SMA Negeri 3 Model Takalar. There are four stage of CAR, (1) planning, (2) action, (3) observation and (4) reflection. The research was done in two cycle. The result showed that TPS learning method could enhance the student’s achievement of class XI MIA.2 SMA Negeri 3 Model Takalar, there are 7 steps are: (1) explain the learning purpose and linking the learning materials with that have been studied previously; (2) giving problem to the student who solved individually by providing the time of think for 15 minutes; (3) Grouping students in parallel and share the results of discussions within the group as a cross; (4) share the group discussion result to the other group by short presentation; (5) provided the test to the students in the form of essay is done by individually to test its capabilities; (6) given the reward in the form of compliment to every student who has the highest score; dan (7) asked the student to summarize the learning result according to the learning purpose. The student’s achievement for cycle I is 62.13% incomplete. The student’s achievement for cycle II is 87.06% complete.Keywords: TPS, Student’s achievement, Acid-base.
ANTINOMY AND PARADOX IN ST. AUGUSTINE’S “CONFESSIONS” AND THE “SHIMMERING CONCEPT” OF L. WITTGENSTEIN
Authors: Vinokurov Vladimir , Vorontsova Marina 
Published: July 2019

The aim is to show the disintegration of a personality by analyzing the fragment of “Confession” by St Augustine. It allows us to come from the phenomenological description of personality transformation process to means of psychological defense. By solving the questions of love St Augustine uses hidden rhetorical constructions, which reflect his emotional processes in the most adequate way. They should be analyzed and clarified.
The rhetorical aspect of this transformation can be reconstructed from that part of “Confession” where Augustine describes his Carthage impressions. He suffers psychological chaos: he “ran into love”, “loving love”. Augustine finally summarizes these impressions by saying “I loved not yet, yet I loved to love”. Thesis becomes antithesis and that is the circle.
Wittgenstein wrote in “Tractatus Logico-philosophicus” (1922), that “a function cannot be its own argument”.
In “Remarks on the Foundations of Mathematics” (1942) Wittgenstein returns to this topic. For the description of this contradiction Wittgenstein proposes a kind of function:”F (F), where F (ξ) = – ξ (ξ)”. It is “a shimmering concept”.
Contradiction is part of logical symbolism, but topologically, the figures of contradictions, which use Augustine and Wittgenstein, are different. They describe a variety of psychological processes.
The figures of contradictions by St Augustine are the paradox in time. The figures of contradictions by L. Wittgenstein are the antinomy in space.
Sosyal-Çevre Bağlamında Kentte Gündelik Yaşam Estetiği, Sanatçıların Gözünden Kuzguncuk Semti
Authors: DURSUN Necla , ATMACA CAN Aynur 
Published: July 2019

Kentleri oluşturan mahalleler tarih boyunca hem mimari hem de sosyal açıdan önemli bir yere sahip olmuştur. Yapısal ve mekânsal olarak kendisine has özellikler taşıyan mahalleler birçok açıdan tarihe ışık tutmaktadır. Bazı mahalleler ise özellikli halini her dönem korumaktadır. İstanbul Üsküdar ilçesinebağlı Kuzguncuk semti bu tür mahallelerdendir. Kamusal alanda sanatla iç içe olan Kuzguncuk’ta sanat müzeden-galeriden çıkarak sokağa, caddeye, meydana eklenmiş; gündelik yaşama dahil olmuştur.Sakinleri ile etkileşim halindeki semtte sanatın bireye ulaşması hayal olmaktan çıkarak gereceğe dönüşmüştür. Çalışma bu çerçevede atölye ve ikamet adresi olarak seçimlerini Kuzguncuk’tan yana kullanan sanatçıların gözünden semt tarihine, sahip olduğu zenginliklere, sanatçıların semte kattıklarıile insan ve mekân etkileşimi bağlamında semti incelemektir.
Bireylerin Satın Alma Davranışında Çevre Bilincinin Belirlenmesi (Tokat Merkez İlçe Örneği)
Authors: YÜZBAŞIOĞLU Rüveyda , KAPLAN Esra 
Published: July 2019

Globalleşen dünyada, çevreye ilişkin problemlerin artış göstermesi, çevreci ürünlere olan ilgi duyarlılığını da beraberinde getirmektedir. Bu bağlamda bireylerin satın alma davranışlarındaki çevre bilincini ortaya koymak amacıyla çalışma çok yönlü incelenerek istatistiki olarak değerlendirmeler yapılmıştır. Bu amaç doğrultusunda bireylerin sosyo-demografik özellikleri incelendikten sonra, satın almadaki bilinç düzeylerini belirlemek için bir takım sorular sorulmuş ve soruların puanlama sistemi uygulanmıştır. Bu puanlama sonucu bireylerin %69.45’i bilinç seviyesi yüksek olarak belirlenmiştir. Bireylerin çevre konularına önem verdiği, çevreye ilişkin haberleri izlediği, çöplerini ayrıştırma konusunda önem gösterdikleri ve ambalajlı ürünlerin etiketlerini okuma hassasiyeti olduğu gözlenmiştir. Bireylerin geri dönüşümlü ürünleri bildiği tanıdığı söylenebilir. Bireylerin çevre kirliliğine ilişkin farkında olunduğunun ancak korunması gereken bilgiler hakkında bilgi eksiliğinin olduğunun, yani bireylerin çevre konularında bilinçli olma potansiyeli olduğu araştırma sonuçları doğrultusunda söylenebilir.
SORVETE VEGANO COM EMULSIFICANTE DE LINHAÇA
Authors: Almeida Lara , Issler Leandra , Petry Marymar , Miotto Bernardi Daniela 
Published: July 2019

SORVETE VEGANO COM EMULSIFICANTE DE LINHAÇA

LARA ALMEIDA¹; LEANDRA ISSLER²; MARYMAR PETRY³; DANIELA MIOTTO BERNARDI4.

1Acadêmica de Nutrição, Centro Universitário Assis Gurgacz – Paraná, laratpalmeida@hotmail.com
2Acadêmica de Nutrição, Centro Universitário Assis Gurgacz – Paraná, leandraissler2@gmail.com
3Acadêmica de Nutrição, Centro Universitário Assis Gurgacz – Paraná, marymarpetrydesouza@hotmail.com
4Nutricionista, Docente Centro Universitário Assis Gurgacz – Paraná, danimiottober@gmail.com.

Introdução: O veganismo vem crescendo, tendo em vista esse aumento, o objetivo foi desenvolver e avaliar sensorialmente um sorvete vegano com bom teor lipídico, rico em gordura boa proveniente da linhaça, além de trazer uma linha mais nutritiva sendo à base de inhame, a fim de atingir além dos veganos, uma população com restrições à lactose e ao glúten. Metodologia: Para a produção foi utilizado o inhame, leite condensado e creme de leite de soja, cacau em pó 100% e gel de linhaça. Para obter o gel da linhaça foram utilizadas 6 colheres de sopa de linhaça em 100 ml de água por 24 horas, após esse conteúdo foi peneirado e assim refrigerado, esse gel serviu como o emulsificante na formulação do sorvete. O inhame foi higienizado, descascado e cortado em tamanhos semelhantes e depois imergido até a cobertura total do mesmo, após o procedimento foi levado ao fogo por aproximadamente 15 a 20 minutos, depois do cozimento a água foi escorrida e o inhame foi colocado em outro recipiente até chegar à temperatura ambiente. Foram elaboradas duas formulações de sorvete, uma com o gel de linhaça (SGL) e a outra sem este gel (SSG), sendo que para elaborar os produtos, o inhame foi colocado no liquidificador e adicionado creme de leite e o leite condensado de soja, o cacau em pó e o gel de linhaça (exclusivo para SGL). Os ingredientes foram liquidificados por aproximadamente 2 minutos, colocados em refrigerador convencional (-5ºC). Os produtos desenvolvidos foram avaliados por meio de uma análise sensorial, onde foram comparados a uma formulação comercial (SC), usando uma escala hedônica estruturada de nove pontos, onde se avaliou aceitação global (AG), aparência (AP), aroma (AR), sabor (SB), textura (TX). Os dados foram analisados estatisticamente utilizando ANOVA e Tukey. Resultados: Verificou-se diferença estatística (p<0,05) para os atributos aparência e textura. Obtiveram-se respectivos dados para (SC) AC 7,5 ± 1,5; AP 7,4 ± 1,6b; AR 7,6 ± 1,6; SB 7,5 ± 1,7; TX 6,9 ± 1,9bc (SGL) AC 7,7 ± 1,5; AP 8,1 ± 1,1a; AR 7,8 ± 1,2; SB 7,6 ± 1,5; TX 7,6 ± 1,9ac (SSG) AG 8,2 ± 0,9; AP 8,5 ± 0,9a; AR 8,2 ± 1,1; SB 7,9 ± 1,2; TX 8,0 ± 1,2a. Conclusão: Foi observado que nos quesitos aroma e sabor as amostras (SGL; SSL) não se diferenciam da amostra comercial (SC) semelhante ou igual ao encontrado no comércio, portanto o produto desenvolvido obteve excelente média de aceitabilidade pelo público em geral.

Palavras-chave: SORVETE; INHAME; LINHAÇA.
ANÁLISE DE ACEITAÇÃO SENSORIAL DE UM PRODUTO A BASE DE AMENDOIM COM CARACTERISTICAS FUNCIONAIS
Authors: Da Silva Vanessa Cristina , Da Silva Sabrine Zambiazi 
Published: July 2019

A paçoca é um doce tradicional de todas as regiões do Brasil, muito procurada principalmente para temporadas de festas juninas, além de muito consumida diariamente, e sua preparação costuma ser à base de amendoim, açúcar e sal. Um alimento funcional é todo aquele que traz benefício fisiológico comprovado juntamente com suas funções nutritivas básicas. O presente estudo objetivou o desenvolvimento de paçocas funcionais visando caracterizar um produto inovador e rico em nutrientes. A metodologia constituiu-se primeiramente em elaborar de forma caseira três formulações de paçocas tendo como base o amendoim, porém, com a adição de chia, aveia, óleo de coco e/ou soja, além de açúcar demerara orgânico, sal e fécula de mandioca. Posterior a produção das mesmas, realizou-se a análise sensorial para verificar a aceitabilidade dos três produtos com diferentes formulações, na qual os avaliadores após provarem as paçocas, responderam um questionamento que avaliou aceitação global, aparência, aroma, sabor e textura com uma escala hedônica de 1 a 9. Teve como resultado desta análise, utilizando ANOVA e a Tukey, com maior média (8,4) para o sabor da P8 (paçoca desenvolvida receita 3), e com menor média (6,8) para a textura da P4 (paçoca desenvolvida receita 1). Soares et.al (2015) desenvolveram três tipos de paçocas utilizando como base o cumbaru, acrescentando soja e linhaça, e obtiveram a maior média de 7,9 quando avaliado o paladar (sabor), entretanto, as formulações não diferiram entre si. Nos atributos de aceitação global, aparência, aroma, sabor e textura, a P6 (paçoca desenvolvida receita 2) e P8 obtiveram a mesma média, sendo acima de 8,0. De acordo com o resultado de valor de p (ANOVA), as amostras foram diferentes entre si (<0,001). Soares (2016) também alcançou uma boa aceitação global no desenvolvimento de três paçocas à base de soja acrescentadas de linhaça, tendo como maior média 7,7 e menor 6,8, havendo também diferença significativa entre as amostras. Conclui-se, com isso, que a P6 e P8 tiveram grande aceitação pelos avaliadores em todos os atributos, podendo assim serem potencialmente, ótimas opções para o mercado, não somente pelo quesito sabor, mas principalmente, em questão nutricional, haja visto que os ingredientes adicionados são considerados funcionais.