bluuebunny/crossref_metadata_2025_split huggingface dataset:
Imaging and histopathological findings of a third metacarpal aneurysmal bone cyst and pathological proximal suspensory ligament avulsion fracture
Authors: Fletcher O. , Mackinder J. , Agass R. , Bianco C. , Ortiz A. , Dixon J. 
Published: November 2024

SummaryA 10‐year‐old Quarter Horse mare presented with acute and severe lameness, persisting despite initial farriery intervention. Upon physical examination, palpation of the proximal thirds of the third and fourth metacarpal bones elicited marked pain. Radiographic evaluation revealed a well‐defined radiolucency within the proximal third of the left third metacarpal bone, localised to the enthesis of the proximal suspensory ligament. Ultrasonographic findings demonstrated moderate thickening and increased vascularity of the suspensory ligament at this level. Surgical intervention was considered; however, its feasibility was constrained by the atypical nature and location of the lesion. Subsequent magnetic resonance imaging (MRI) provided a detailed characterisation of the lesion, confirming its expansile nature and the suspected associated avulsion fracture presence. Histopathological examination corroborated the diagnosis of an aneurysmal bone cyst (ABC) with an accompanying bone fracture and bone remodelling. Cases like the one described here define the importance of utilising advanced imaging techniques in combination with conventional modalities, especially when diagnosing and assessing the extent of unusual or complex lesions, to inform prognosis and guide treatment decisions. Due to the lesion's intramedullary location, expansile nature and involvement of critical anatomical structures, surgical interventions were limited which led to a recommendation for humane euthanasia.
Facebook and Consumer Research: A Review, AI‐Driven Thematic Visualisation, and Research Agenda
Authors: Zaveri Moulik , Wilk Violetta 
Published: November 2024

ABSTRACTThis paper explores the evolution of academic consumer research on Facebook by consolidating the existing body of literature. The study consists of 336 papers on the topic of Facebook and consumers, published in top journals between 2008 and 2023, sourced via Scopus. The data collection followed the PRISMA framework, and bibliometric analysis was conducted using descriptive and performance analyses with the aid of data tabulation software. Additionally, natural language processing (NLP) and thematic analysis of the data were conducted via text mining, topic modelling and data visualisation with Leximancer—an artificial intelligence (AI)‐based programme. The results revealed that, over the 15‐year time period, and most prominently in the last 5 years, there has been a noticeable shift in consumer research on Facebook in line with the evolution of the social media platform itself. The paper identifies evident gaps in the literature via thematic analysis of future research suggestions and managerial implications emergent from the data. It proposes specific future research directions for academic researchers to explore. Practitioners are provided insights corresponding to consumer‐centric and effective social media marketing strategies.
For the Greater Good: When Visionary Leadership Fosters Follower Moral Elevation and Unethical Prosocial Behavior
Authors: Buss Martin , Kearney Eric 
Published: November 2024

ABSTRACTWhile previous research has mostly focused on visionary leadership's positive effects, real‐world examples suggest that such leadership might sometimes also cause followers to engage in unethical prosocial behavior to contribute to a vision's noble cause. However, the process and the conditions under which this occurs are poorly understood. We draw on the theory of motivated moral reasoning to argue that visionary leadership promotes follower moral elevation and, in turn, follower unethical prosocial behavior, but that this effect is contingent on the follower's dispositional tendency for perspective‐taking. In two experimental studies, we show that visionary leadership only has a positive effect on unethical prosocial behavior through moral elevation among followers with a high dispositional tendency for perspective‐taking. Our work identifies the specific mechanism through which visionary leadership is related to unethical prosocial behavior as well as an important boundary condition of this effect. Moreover, it integrates the respective literatures on visionary leadership, moral emotions, and moral judgment.
Development of Machine Learning Algorithms for Identifying Patients With Limited Health Literacy
Authors: Koole Dylan , Shen Oscar , Lans Amanda , de Groot Tom M. , Verlaan J. J. , Schwab J. H. 
Published: November 2024

ABSTRACTRationaleLimited health literacy (HL) leads to poor health outcomes, psychological stress, and misutilization of medical resources. Although interventions aimed at improving HL may be effective, identifying patients at risk of limited HL in the clinical workflow is challenging. With machine learning (ML) algorithms based on readily available data, healthcare professionals would be enabled to incorporate HL screening without the need for administering in‐person HL screening tools.Aims and ObjectivesDevelop ML algorithms to identify patients at risk for limited HL in spine patients.MethodsBetween December 2021 and February 2023, consecutive English‐speaking patients over the age of 18 and new to an urban academic outpatient spine clinic were approached for participation in a cross‐sectional survey study. HL was assessed using the Newest Vital Sign and the scores were divided into limited (0–3) and adequate (4–6) HL. Additional patient characteristics were extracted through a sociodemographic survey and electronic health records. Subsequently, feature selection was performed by random forest algorithms with recursive feature selection and five ML models (stochastic gradient boosting, random forest, Bayes point machine, elastic‐net penalized logistic regression, support vector machine) were developed to predict limited HL.ResultsSeven hundred and fifty‐three patients were included for model development, of whom 259 (34.4%) had limited HL. Variables identified for predicting limited HL were age, Area Deprivation Index‐national, Social Vulnerability Index, insurance category, Body Mass Index, race, college education, and employment status. The Elastic‐Net Penalized Logistic Regression algorithm achieved the best performance with a c‐statistic of 0.766, calibration slope/intercept of 1.044/−0.037, and Brier score of 0.179.ConclusionElastic‐Net Penalized Logistic Regression had the best performance when compared with other ML algorithms with a c‐statistic of 0.766, calibration slope/intercept of 1.044/−0.037, and a Brier score of 0.179. Over one‐third of patients presenting to an outpatient spine center were found to have limited HL. While this algorithm is far from being used in clinical practice, ML algorithms offer a potential opportunity for identifying patients at risk for limited HL without administering in‐person HL assessments. This could possibly enable screening and early intervention to mitigate the potential negative consequences of limited HL without taxing the existing clinical workflow.
Shared decision‐making about autologous stem cell transplantation: A qualitative study of older patients and physicians
Authors: Liu Qian , Li Jianfang , Wang Lixiu , Shan Chuyue , Wang Li , Ye Dan , Luo Dan , Zou Huijing , Yang Bing Xiang , Wang Xiao Qin , Zhang Jingjing , Zhou Fuling 
Published: November 2024

AbstractBackgroundThe decision‐making process between autologous hematopoietic stem cell transplant (autoHSCT) and less‐intensive treatments necessitates shared decision‐making between older patients with hematological malignancies and healthcare providers. However, there is limited knowledge from both perspectives. This qualitative study aimed to comprehensively understand the experiences of shared decision‐making regarding autoHSCT among older patients with hematological malignancies and physicians.MethodsOlder patients and physicians were recruited from the hematology department at one of the affiliated general hospitals of Wuhan University. They participated in semi‐structured, in‐depth face‐to‐face individual interviews from August 2022 to March 2023. The interviews explored their experiences with shared decision‐making about autoHSCT. Interviews were transcribed verbatim and analyzed using Colaizzi's phenomenological method.ResultsThirteen older patients and eight physicians were recruited. Two themes were identified: (1) Factors influencing AutoHSCT recommendations and decision‐making: Seven factors were categorized into three groups: physician‐driven factors (pretransplant assessments, experience‐based judgment, and communication approaches), patient‐driven factors (perceived benefits and risks, financial challenges, and family involvement), and mutual trust between patients and physicians, which is a bidirectional factor relying on both physicians' trust and the active participation of patients in the decision‐making process. (2) Treatment planning and outcome expectations: Regardless of treatment choices, patients focused on engaging in self‐management and prioritizing quality of life, and maintaining hope for positive outcomes.ConclusionsThe shared decision‐making process for autoHSCT between older patients with hematological malignancies and physicians is shaped by physician‐driven factors, patient‐driven factors, and mutual trust. These findings provide a foundation for developing patient‐centered care strategies, including decision aids and enhanced communication training for physicians, aimed at improving outcomes for older patients facing complex treatment choices. Future research should explore how these factors interact over time, through longitudinal studies, to assess their long‐term impact on patient outcomes and quality of life.
Characterization of national eco‐industrial park projects in China, Korea, and Japan: Bibliometric analysis and systematic literature review
Authors: Putra Agusta Samodra , Dong Liang , Park Yujin , Park Hung‐Suck 
Published: November 2024

AbstractEco‐industrial parks (EIPs) promote sustainable industrial development by integrating environmental, economic, and social objectives. China, Japan, and Korea have reported significant achievements on EIPs. This paper conducted an integrated bibliometric analysis and systematic literatures review to characterize their national EIP initiatives and draw out their success factors. The bibliometric analysis was conducted on EIP research articles from 1998 to 2022, with keywords related to locally specified EIPs plus the country name. Three hundred and sixty‐one peer‐reviewed articles (China: 300; Korea: 30; and Japan: 31) are analyzed. Keywords analysis highlighted “environmental benefit,” “carbon emission,” and “eco‐industrial development” for China; “symbiosis,” “society,” and “recycling industry” for Japan; and “symbiosis network,” “emission,” and “eco‐industrial parks” for Korea. These results well match with the fact that China's EIP was featured as establishing centralized industrial infrastructure facilitated by circular economy and environmental policies. Korean EIP focused on building industrial symbiosis (IS) networks by business model, emphasizing EIP transition. Eco‐town program in Japan emphasized waste recycling and landfill minimization to promote eco‐innovation with environmental technology advancement. The in‐depth literature review of these EIP programs based on the evolution, planning, implementation, and evaluation presents the specific characteristics of the EIP program in each country. All the programs are incorporated into national policy and development strategy with specific financial support and incentives for project incubation, enabling scheme and business model for project scale up, as well as collaborative government (central and local) and public–private partnership in their contexts. These lessons are expected to be customized based on the target countries’ situations to scale up and mainstream EIP implementation globally.
Social traps and the wicked problem of single‐use plastics: A marketing, policy, and consumer‐citizen perspective
Authors: Shultz Clifford J. , Mason Marlys J. , Fehl Amy Greiner , Baker Stacey Menzel , Barakat Karine Aoun , Bone Sterling A. , Thomas Meredith Rhoads 
Published: November 2024

AbstractWicked problems pose both immediate and existential threats. Within this article we explore the underlying nature of wicked problems, including the social traps embedded in them. We deconstruct the ecosystem surrounding single‐use plastics to make key points regarding controversies and conflicting interests surrounding wicked problems. We propose that wicked problems may be reframed by unpacking the relationships between individuals and collectives and how social traps are understood in terms of time horizon, ownership, responsibility, and involvement. We argue that resolutions to social traps are paramount to resolving wicked problems in the case of single‐use plastics and to wicked problems more generally. We draw from marketing, psychology, public policy, and consumer research literature to suggest specific ways marketing can mitigate or perhaps eliminate the insidious dynamic of social traps and wicked problems, and in turn affect positive outcomes to enhance the short‐term and long‐term well‐being for many consumers and stakeholders.
Efficacy and Safety of Combination Therapy of Microneedling Radiofrequency, In‐Office and Home‐Based Topical Cysteamine in Refractory Melasma: A Split Face, Vehicle‐Control, Randomized Control Trial
Authors: Tsai Ya‐Wen , Lin Jeng‐Hsien , Lai Yi‐Jing , Liu Tzu‐Li , Ng Chau Yee 
Published: November 2024

ABSTRACTBackgroundRefractory melasma remains a challenge in dermatology, necessitating the exploration of innovative treatments.AimsThis study aims to evaluate the efficacy and safety of combining radiofrequency microneedling (RFM) with Cysteamine cream, applied both in‐office and as a part of a home‐care regimen, to treat refractory melasma.Patients/MethodsA vehicle‐controlled, split‐face trial was conducted on 30 Fitzpatrick skin types III and IV participants. Subjects received RFM and Cysteamine serum on one side of the face and RFM with saline on the contralateral side. Additionally, a random half‐added Cysteamine cream was applied at home. The modified Melasma Area and Severity Index and VISIA skin analysis were used for assessment.ResultsSignificant improvement in melasma severity and skin texture was noted on the sides treated with RFM and Cysteamine, including observable benefits from both in‐office and home‐based Cysteamine use with minimal adverse effects.ConclusionsThe combined approach of RFM with Cysteamine provides a promising and safe modality for managing refractory melasma, showing notable improvements.
Revealing the Therapeutic Potential: Investigating the Impact of a Novel Witch Hazel Formula on Anti‐Inflammation and Antioxidation
Authors: Liu Xue , Hage Tamer‐Whittle , Chen Li‐Chi , Wang Eddy Hsi Chun , Liao I‐Chien , Goldberg Jodi , Gosto Sabina , Cziryak Paula , Senna Maryanne , Chen Ying , Zheng Qian 
Published: November 2024

ABSTRACTBackgroundSkin barrier health is crucial for preventive and corrective skincare across all skin types. Witch hazel (Hamamelis virginiana) extracts show potential in addressing skin issues, but their efficacy in treating chronic inflammation, improving skin barrier function, and combating UV‐induced oxidation requires further investigation.AimsTo evaluate the efficacy of a novel formula containing witch hazel extracts in treating chronic inflammation, improving skin barrier function, and combating UV‐induced oxidation.MethodsWe employed a novel ex vivo chronic inflammation model to assess anti‐inflammatory effects, measuring key pro‐inflammatory cytokines. Barrier function markers, such as loricrin and transglutaminase‐1, were analyzed. An ex vivo model with UV‐induced Reactive Oxygen Species (ROS) elevation was used to evaluate antioxidant properties, measuring specific ROS markers like 4‐Hydroxynonenal and carbonylated protein.ResultsThe novel witch hazel formula significantly reduced pro‐inflammatory cytokines in both 2D and ex vivo models, including IL‐6 and IL‐8, demonstrating potent anti‐inflammatory effects. Barrier function markers showed notable improvements compared to the inflamed condition. In the UV‐induced ROS model, the formula remarkably decreased ROS levels, specifically 4‐Hydroxynonenal and carbonylated protein, indicating strong antioxidant properties.ConclusionsOur findings demonstrate that the novel witch hazel formula exhibits potent anti‐inflammatory and antioxidant properties while enhancing skin barrier function. This natural, well‐tolerated ingredient offers a promising treatment option for improving overall skin health, presenting new opportunities in skincare formulation and treatment strategies.
Mobile Health to Improve Efficacy of Interdental Brushing Among Periodontitis Patients: A Randomized Clinical Trial
Authors: Yadav Jyoti , Tanwar Nishi , Sharma Rajinder Kumar , Sangwan Aditi 
Published: November 2024

ABSTRACTAimCompliance with plaque control measures in open interdental spaces, an essential element in management of periodontitis, is reported to be poor. Mobile health (mHealth) approach is an effective approach for behavior change. This study aimed to assess the effectiveness of mHealth in improving plaque control in type 2 embrasures.MethodsStage II or III, grade B periodontitis patients (n = 76) with type 2 embrasures were enrolled. Phase I therapy was provided in both groups. In the control group, interdental brushing instructions were given only at baseline and follow‐up appointments. In the test group, interdental brushing was also reinforced by regular text messages for 3 months. Clinical parameters including plaque index (PI), papillary bleeding index (PBI), probing pocket depth (PPD), clinical attachment level (CAL), gingival index (GI), bleeding on probing (BOP), and interdental papillary height (IPH) were measured at baseline, 1, 3, and 6 months.ResultsIntergroup comparison from baseline to 6 months showed a statistically significant difference (p < 0.05) between groups in all parameters with more reduction in mean values in test group. Intergroup comparison from 3 to 6 months showed a statistically significant difference (p < 0.05) in mean values of PI, PBI, GI, PPD, CAL, and IPH with higher reduction in test group. Intragroup comparison from 3 to 6 months showed statistically significant reduction in mean values in PI, PBI, PPD, CAL, and IPH only in test group (p < 0.05).ConclusionCue to action through mobile text messages effectively augments compliance with the use of interdental brush, improves plaque control, and manages stage II or stage III periodontitis following subgingival instrumentation.Trial RegistrationClinicalTrials.gov identifier: NCT05565404
Salivary peptidomic profiling of chronic gingivostomatitis in cats by matrix‐assisted laser desorption/ionization‐time‐of‐flight mass spectrometry and nanoscale liquid chromatography‐tandem mass spectrometry
Authors: Ploypetch Sekkarin , Pornthummawat Apisit , Roytrakul Sittiruk , Jaresitthikunchai Janthima , Phaonakrop Narumon , Wardhani Sabrina Wahyu , Lacharoje Sitthichok , Techangamsuwan Somporn 
Published: November 2024

AbstractBackgroundChronic gingivostomatitis in cats (FCGS) is a moderately to severely painful condition, potentially caused by inadequate immune response to oral antigenic stimulation. Salivary peptidome analysis can identify inflammatory protein mediators and pathways involved in oral mucosal immune activation and may indicate potential therapeutic options for FCGS.ObjectiveEvaluate the diversity and abundance of salivary peptides in cats with FCGS using matrix‐assisted laser desorption/ionization‐time‐of‐flight mass spectrometry (MALDI‐TOF MS) and nanoscale liquid chromatography‐tandem mass spectrometry (nano LC‐MS/MS).AnimalsThirty‐two cats with FCGS and 18 healthy controls.MethodsCase‐control cross‐sectional study. We compared the salivary peptide profiles of diseased and healthy cats. The diagnosis of FCGS was confirmed by histopathology. Saliva samples were analyzed for viral infections using polymerase chain reaction (PCR), peptide mass fingerprint (PMF) using MALDI‐TOF MS, and peptide identification using nano LC‐MS/MS.ResultsDistinct clusters of peptide profiles were observed between groups. In FCGS, 26 salivary peptides were altered, including apolipoprotein A1, nuclear receptor subfamily 1 group I member 3, fibrinogen alpha chain, interleukin 2 receptor gamma, interleukin 23 receptor, hemoglobin subunit alpha, and serpin peptidase inhibitor clade A (alpha‐1 antiproteinase, antitrypsin) member 12, protein‐tyrosine‐phosphatase, and cholinergic receptor nicotinic alpha 10 subunit. Protein‐anti‐inflammatory drug interaction networks were observed.Conclusions and Clinical ImportancePeptide mass fingerprint and peptide profiles identified distinct clusters between FCGS and healthy cats. The 9 novel salivary peptide markers were associated with the JAK/STAT and PI3K/Akt pathways and immune responses. These potentially noninvasive biomarkers may facilitate understanding of FCGS pathophysiology and guide future therapeutic research.
An opportunity for abolition: McCleskey, innocence, and the modern death penalty decline
Authors: Drummond Clayton B. , Norris Robert J. 
Published: November 2024

AbstractFor more than two decades after Gregg v. Georgia (1976), use of the death penalty greatly expanded across the United States. Since 2000, however, it has declined significantly. Perhaps the most notable explanation for this decline is the contemporary focus on wrongful convictions. In this paper, we aim to contextualize the modern death penalty decline, and its connection with innocence, through the theoretical lens of social movements and collective action. We argue that dual opportunities reshaped the modern anti‐death penalty movement. First, the McCleskey v. Kemp (1987) ruling affirmed the federal courts' resistance to abolition and inspired activists to begin shifting toward state‐level political abolitionism. Activists then took advantage of the developing interest in wrongful convictions. Specifically, innocence‐related abolitionist activities in Illinois reinvigorated the anti‐death penalty movement, expanded the advocacy network, and fundamentally reframed the debate around capital punishment in the United States. We suggest that, collectively, these dual opportunities reshaped the anti‐death penalty movement into one that emphasized strategies reaching beyond constitutionality and propelled the movement into the twenty‐first century with a foundation for successful political abolitionism.