bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of Entrepreneurial Orientation on Types of Process Innovation Capabilities and Moderating Role of Social Capital
Authors: Dost Mir , Arshad Muhammad , Afsar Bilal 
Published: July 2018

Abstract
Innovation either in products or processes requires innovation capability. Such ability, as a result, facilitates firms to succeed and gain competitive advantage in the industry by improving their efficiency of creating and marketing products and/or services. In this context, current research examines how risk-taking and proactivity dimensions of entrepreneurial orientation influence types of process innovative capabilities; and to what extent this relationship is strengthened/weakened by social capital. Authors collected data from chemical manufacturing firms of Pakistan, and carefully analyzed it with multiple regression technique. The findings revealed that proactivity and risk-taking facilitate incremental and radical process innovation. The moderation of social capital further strengthened the impact proactivity had on radical process innovation. However, moderation of social capital did not strengthen the impact risk-taking had on incremental and radical process innovation. Surprisingly, social capital demonstrated significantly positive impact on radical process innovation. The paper also discusses the theoretical and managerial implications.
N-Lusin property in metric measure spaces: A new sufficient condition
Authors: Garriga Marcela , Ochoa Pablo 
Published: July 2018

Abstract
In this work, we are concerned with the study of the N-Lusin property in metric measure spaces. A map satisfies that property if sets of measure zero are mapped to sets of measure zero. We prove a new sufficient condition for the N-Lusin property using a weak and pointwise Lipschitz-type estimate. Relations with approximate differentiability in metric measure spaces and other sufficient conditions for the N-Lusin property will be provided.
Low Phase Noise Feedback Oscillators Utilizing High-Q SIW Filter with Dielectric Loading
Authors: Zhang Hao , Kang Wei , Wu Wen 
Published: July 2018

Abstract
High-Q substrate integrated waveguide (SIW) resonator and its application to low phase noise oscillators are focused in this paper. By drilling air holes in the substrate, SIW bandpass filters (BPFs) with high Q factor could be achieved. This SIW filter is embedded into the feedback loop to be treated as a frequency stabilization element in designing the oscillator. The complex quality factor (Qsc)-peak frequency of the filter is chosen as the final oscillation frequency to obtain low phase noise performance. Moreover, air boxes are utilized instead of the air holes in the substrate to design another oscillator with lower phase noise performance and good harmonic suppression. Two low phase noise oscillators based on fourth-order SIW BPFs with dielectric loading have been studied, demonstrated and fabricated to verify the design concept.
Synthesis of dibenzothiazepine analogues by one-pot S-arylation and intramolecular cyclization of diaryl sulfides and evaluation of antibacterial properties
Authors: Shimotori Yasutaka , Hoshi Masayuki , Murata Mari , Ogawa Narihito , Miyakoshi Tetsuo , Kanamoto Taisei 
Published: July 2018

Abstract
Dibenzothiazepine analogues containing lactam, amidine and imine moieties were prepared from 2-aminophenyl disulfides via one-pot S-arylation. The S-arylation involved cleavage of an S-S bond of disulfides and SNAr reaction in aqueous ammonia solution of L-cysteine to afford diaryl sulfides. Dibenzothiazepine analogues having lactam and amidine moieties were obtained by cyclization of the corresponding diaryl sulfides under acidic conditions. One-pot S-arylation of 2-bromo-5-nitrobenzaldehyde gave dibenzothiazepine analogues with an imine moiety in one step through intramolecular cyclization. Compounds with antibacterial activities against Staphylococcus aureus and Escherichia coli were obtained.
Effects of thermal modification on the physical, chemical and micromechanical properties of Masson pine wood (Pinus massoniana Lamb.)
Authors: Wang Xinzhou , Chen Xuanzong , Xie Xuqin , Wu Yan , Zhao Linguo , Li Yanjun , Wang Siqun 
Published: July 2018

Abstract
In an attempt to evaluate the effects of thermal treatment on wood cell walls (CWs), Masson pine (Pinus massoniana Lamb.) wood was thermally modified (TM) at 150, 170 and 190°C for 2, 4 and 6 h, respectively. The chemical properties, cellulose crystallinity (C
rI) and micromechanics of the control and thermally modified wood (TMW) were analyzed by wet chemical analysis, X-ray diffraction and nanoindentation. The relative lignin content and C
rI increased after the TM partly degraded the amorphous wood polymers. The relative lignin content was higher in TMW and the equilibrium moisture content decreased. Moreover, the elastic modulus (E
r) and hardness (H) of TMW were lowered along with the creep ratio decrement (C
IT) of CWs. However, a severe treatment (e.g. 190°C/6 h) may negatively affect the mechanical properties of CWs caused by the partial degradation of hemicelluloses and also cellulose.
Enhancing resin efficiency in plywood production via DBD plasma treatment and atomized air spray of UF resin
Authors: Cao Yizhong , Zhou Xiaoyan , Chen Minzhi , Chen Weimin , Yu Peijing , Thiphuong Nguyen 
Published: July 2018

AbstractTo improve resin efficiency in plywood production, the veneer surface was modified by dielectric barrier discharge (DBD) plasma and the resin was applied by air spray atomization. The droplet size and coverage of resin droplets were evaluated by image analysis. This novel approach improved the resin efficiency. The shear strength of the produced plywood was improved along with a higher gluing speed. The surface energy of poplar veneer altered after plasma treatment, resulting in an increased size of resin droplets and increased resin coverage. Plywood produced at a plasma-processing power of 4.5 kW exhibited the highest shear strength and a 6 kW plasma-processing power did not bring about advantages. Under these circumstances, the lowest amount of resin necessary for fabricating quality products can be reduced to 50 g m−2.
MAC30 knockdown involved in the activation of the Hippo signaling pathway in breast cancer cells
Authors: Song Guo-Qing , Zhao Yi 
Published: July 2018

Abstract
Down-regulation of the meningioma-associated protein (MAC30) gene has been found in many solid cancers. This study was carried out to determine the roles and the mechanisms of MAC30 in breast cancer. We used our own data and a public database to analyze the MAC30 mRNA and protein levels in breast cancer tissues. In addition, we established MAC30 knockdown breast cancer cells using MAC30 siRNA. The roles of MAC30 were detected by using the Soft agar assay, Annexin-V-FITC/PI double staining and the Transwell assay. Western blotting was used to analyze the potential mechanism(s) of MAC30 in these cells. We found that MAC30 mRNA and protein were higher in the cancer tissues compared to the matched normal tissues. MAC30 expression was associated with tumor size, tumor differentiation and estrogen receptor (ER) status. Overall survival rate of the patients with low MAC30 expression was obviously higher than the ones with high expression. The apoptotic ratio was lower in MDA-MB-231 and MDA-MB-157 cells with MAC30 expression. By Western blot analysis, we found that increased levels of phosphorylated YAP1, MST1 and LATS1 after MAC30 siRNA transfection in these two cells. In summary, we demonstrate that MAC30 knockdown is involved in the activation of the Hippo signaling pathway.
A Spatio-Temporal Model and Inference Tools for Longitudinal Count Data on Multicolor Cell Growth
Authors: Qiao PuXue , Mølck Christina , Ferrari Davide , Hollande Frédéric 
Published: July 2018

Abstract
Multicolor cell spatio-temporal image data have become important to investigate organ development and regeneration, malignant growth or immune responses by tracking different cell types both in vivo and in vitro. Statistical modeling of image data from common longitudinal cell experiments poses significant challenges due to the presence of complex spatio-temporal interactions between different cell types and difficulties related to measurement of single cell trajectories. Current analysis methods focus mainly on univariate cases, often not considering the spatio-temporal effects affecting cell growth between different cell populations. In this paper, we propose a conditional spatial autoregressive model to describe multivariate count cell data on the lattice, and develop inference tools. The proposed methodology is computationally tractable and enables researchers to estimate a complete statistical model of multicolor cell growth. Our methodology is applied on real experimental data where we investigate how interactions between cancer cells and fibroblasts affect their growth, which are normally present in the tumor microenvironment. We also compare the performance of our methodology to the multivariate conditional autoregressive (MCAR) model in both simulations and real data applications.
Trimetallic RuxMoNi Catalysts Supported on SBA-15 for the Hydrodesulfurization of Dibenzothiophene
Authors: Torres-García N.L. , Huirache-Acuña R. , Zepeda-Partida T.A. , Pawelec B. , Fierro J.L.G. , Vázquez-Salas P.J. , Maya-Yescas R. , Rivera-Garnica J.M. 
Published: July 2018

Abstract
In this work, novel trimetallic catalysts based on transition metal sulphides (Ru, Mo and Ni) supported on SBA-15 were synthesized. Citric acid (CA) was used as chelating agent in order to enhance the dispersion of the active phase and minimize the metal-support interaction. Sulfided catalysts were evaluated in the reaction of hydrodesulfurization (HDS) of dibenzothiophene (DBT) at 320 °C and 54.5 atm of total H2 pressure. The effects of different Ru/(Ni + Mo) atomic ratios on the active phase were studied. The catalysts were characterized using Micro-Raman spectroscopy, DRIFTS, XRD, XPS, HR-TEM and SEM techniques. Results have shown that there was a better dispersion of the metallic phases, which improves the physicochemical properties of the catalysts, increasing the catalytic activity. The trimetallic RuxMoNi catalyst with the lowest atomic ratio, have shown superior catalytic activity compared to their higher atomic ratio counterparts. The interaction of the chelating agent improved the catalytic activity, which was superior to that observed for NiMo based catalysts, considered one of the most active hydrotreating catalysts.
Impact of Temperature, Gum Arabic and Carboxymethyl Cellulose on Some Physical Properties of Spray-Dried Grapefruit
Authors: González Freddy , Igual Marta , Camacho María del Mar , Martínez-Navarrete Nuria 
Published: July 2018

Abstract
Spray-dried fruit powder may be an interesting alternative for the purposes of promoting fruit consumption among consumers. The use of carrier agents is especially necessary for the production of spray-dried fruit powders. As they may affect some physical properties of the powder, it is important to adjust the amount at which they have to be added to the minimum in order to achieve the necessary effects. The final aim of the study was to identify the most suitable atomization temperature, as well as the optimal concentration of gum Arabic (GA) and carboxymethyl cellulose (CMC) to be used as carriers, in order to obtain grapefruit powder with the maximum dry matter yield (DMY) and porosity, the minimum water content and, simultaneously, with suitable color characteristics. The results of the study don’t recommend the use of CMC and suggest that the best color, the one that corresponds to a free-flowing powder, corresponds to a very luminous one, low in chroma and with a hue that is much more yellow than reddish orange.
The acquisition of Mandarin sentence final particles by Italian learners
Authors: Badan Linda , Romagnoli Chiara 
Published: July 2018

AbstractThis article deals with the acquisition of four Mandarin sentence final particlesma, a, ba, neby Italian native speakers. The research gives a contribution to the study of sentence final particles from an acquisition and didactic perspective, which has been scarcely investigated in the linguistic literature. The article proposes a quantitative and qualitative experimental analysis with two groups of Italian learners, one at elementary proficiency level and one at intermediate level. The research shows thatneandbaare the most challenging particles to acquire by Italian learners. We argue that this due to the fact thatneandbaare highly polyfunctional and they do not simply determine the type of clause. The functions ofneandbatested in this paper, in fact, are better defined as discourse particles, whose meaning is highly dependent from the context. Moreover, the experiment demonstrates not only that the proficiency level is straightforward correlated to the mastery of sentence final particles, as expected, but also that the didactic tools play a crucial role. As a matter of fact, the results of this study opens up a number of pedagogical implications in relation to the teaching of Mandarin sentence final particles to Italian learners.
The Future of Demand for Food Away from Home and Prepared Food: Cohort and Age Effects in Japan
Authors: Fujioka Soichiro , Fukushige Mototsugu 
Published: July 2018

Abstract
The demand for two composite goods, food away from home (FAFH) and prepared food (PF), are trending upward in Japan as Japanese society ages. This paper estimates the demand function of FAFH and PF. We adopt the almost ideal demand system and predict the effect on future demand from age and cohort changes. We find that the age effect decreases both while the cohort effect increases the share of FAFH but decreases that of PF. Over time, the demand for FAFH gradually decreases but remains stable. The demand for PF has been decreasing as of 2010 and more quickly than for FAFH. The reason is that both the age effect and the dynamic population trend decrease the demand for both goods, while the cohort effect slows the decrease in demand for FAFH but accelerates that for PF.
High-fat diet modifies cytokine gene expression and exacerbates the effects of acute pancreatitis in the liver of rats
Authors: Abdelsadik Ahmed 
Published: July 2018

Abstract

Background:
Obese patients have a higher risk of developing different metabolic syndromes (MeS), including acute pancreatitis (AP). Although obese individuals are more prone to MeS and more susceptible to local and systemic inflammation in response to AP, thus causing long-lasting hospitalization, higher morbidity and mortality, their underlying mechanisms remain unclear. This study aimed to investigate the relationship between obesity and the outcomes of AP in the rat model of AP.

Methods:
To assess the link between obesity and AP, 40 male albino rats were divided into two groups: control and those given a high-fat diet for 12 weeks. This was followed by the injection of a single dose of L-arginine (250 mg/100 gm) in half of each group to induce AP.

Results:
Data evaluation was done using 2-way ANOVA. Values were considered significant when p≤0.05. Markers of AP were evaluated in the serum and ascitic fluid. Moreover, the systemic inflammatory markers, such as IL-6, TNF-α, HMGB1 and TLR4, were quantified in the liver of all groups. Results showed that the OAP group had the highest levels of liver enzymes and amylase aside from several signs of liver damage, such as fat necrosis and steatosis.

Conclusions:
The inflammatory cytokine levels are synchronized, creating an early responsive stage and late inflammatory stage to realize the best defense mechanism. Results also indicate that obesity is a main determinant of the severity of AP at the late stage.
From Virtual Reality to Immersive Analytics in Bioinformatics
Authors: Sommer Björn , Baaden Marc , Krone Michael , Woods Andrew 
Published: July 2018

Abstract
Bioinformatics-related research produces huge heterogeneous amounts of data. This wealth of information includes data describing metabolic mechanisms and pathways, proteomics, transcriptomics, and metabolomics. Often, the visualization and exploration of related structural – usually molecular – data plays an important role in the aforementioned contexts. For decades, virtual reality (VR)-related technologies were developed and applied to Bioinformatics problems. Often, these approaches provide “just” visual support of the analysis, e.g. in the case of exploring and interacting with a protein on a 3D monitor and compatible interaction hardware. Moreover, in the past these approaches were limited to cost-intensive professional visualization facilities. The advent of new affordable, and often mobile technologies, provides high potential for using similar approaches on a regular basis for daily research. Visual Analytics is successfully being used for several years to analyze complex and heterogeneous datasets. Immersive Analytics combines these approaches now with new immersive and interactive technologies. This publication provides a short overview of related technologies, their history and Bioinformatics-related approaches. Six new applications on the path from VR to Immersive Analytics are being introduced and discussed.
Intervention for physician burnout: A systematic review
Authors: Wiederhold Brenda K , Cipresso Pietro , Pizzioli Daniele , Wiederhold Mark , Riva Giuseppe 
Published: July 2018

AbstractBurnout is an important problem for physicians, with a strong impact on their quality of life and a corresponding decrease in the quality of care with an evident economical burden for the healthcare system. However, the range of interventions used to decrease this problem could be very fragmented and with the aim to shed some light on this issue, this study reviews and summarizes the currently available studies. We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines to identify studies about intervention on physician burnout. Two authors independently searched into scientific databases to analyze and review the full papers that met the inclusion criteria. As a result, from an initial search of 11029 articles, 13 studies met full criteria and were included in this review. Of the 13 studies presented, only 4 utilized randomized controlled trials, therefore the results should be interpreted with caution. Future interventions should focus on a more holistic approach using a wider range of techniques. According to the studies selected in this review, it appears that a successful intervention for burnout should take into account the broad range of causes incorporating a variety of therapeutic tools.
Clinical effects of piribedil in adjuvant treatment of Parkinson’s Disease: A meta-analysis
Authors: Peihua Lu , Jianqin Wang 
Published: July 2018

Abstract
Objective. To evaluate the clinical effects of piribedil in adjuvant treatment of Parkinson’s Disease (PD) by pooling previously openly published studies. Methods. The related electronic databases of Medline (1960~2017.5), Cochrane central register of controlled trials (CENTRAL), EMBASE (1980~2017.5) and Wanfang (1986~20175.5) were searched by two reviewers (Lu Peihua and Wang Jianqian) independently for publications including the topic of prospective randomized controlled trials about clinical effects of piribedil in adjuvant treatment of PD. The data of each included study was extracted and pooled by Stata11.0 software (for meta-analysis). The statistical heterogeneity across the studies was evaluated by I2 test and the publication bias was calculated by begg’s funnel plot and Egger’s line regression test. Results. After searching the related electronic databases of Medline, CENTRAL, EMBSE and Wanfang databases, 11 clinical studies were included in this meta-analysis. The pooled RR (random effect model) of clinical efficacy was 1.29 (95%CI:1.18~1.41, P=4×10-3) indicating the clinical efficacy of piribedil group was signficat higher than those of control group. The standard mean difference (SMD) for UPDRS score changed before and after treatment was pooled by random effect model. The combined SMD was -0.41 (95%CI:-0.75~-0.06). For piribedil related side effects, the combined data indicated that there was no statistical difference for nausea and vomiting (RR=0.43, 95%CI:0.41~1.69, P=0.61), mental disorders (RR=0.85, 95%CI:0.45~1.59, P=0.61) and other toxicities (RR=0.32, 95%CI:0.09~1.16, P=0.08). Conclusion. Piribedil combined with Levodopa in adjuvant treatment of PD is more effective than Levodopa alone without increasing the drug related toxicity.
Identification of a novel BRAF Thr599dup mutation in lung adenocarcinoma
Authors: Zhang Xuefei , Li Mo , Lv Desheng , Sun Ge , Bai Yu , Tian Hui , Liu Changhong 
Published: July 2018

Abstract
BRAF mutations are known as oncogenic drivers of non-small cell lung cancer (NSCLC). BRAF inhibition has demonstrated anti-tumor activity in patients with BRAF V600E mutant NSCLC. Further molecular screening for novel BRAF thr599dup mutation is warranted. The novel BRAF Thr599dup gene mutation, for which the repeat amino acid-tyrosine is inserted between the 599th amino acid and the 600th amino acid in exon 15 of BRAF, was identified by next-generation sequencing (NGS) during routine clinical care in a lung carcinoma sample from an Asian never-smoker. Other putative driver alterations including EGFR, ALK were not found in that patient. BRAF Thr599dup gene mutation analysis was consistent with BRAF v600E gene mutation. Here we report a novel BRAF gene mutation with molecular characteristics consistent with those in BRAF-driven NSCLC. Our case expands the scope of BRAF gene mutations and provides broader molecular profiling for optimizing therapeutic options for patients with NSCLC. The new BRAF gene mutation has important clinical meaning for cancer patients.
Structural and optical characterization of annealed As30Te60Ga10 thin films prepared by thermal evaporation technique
Authors: Abd-Elnaiem A.M. , Mohamed M. , Hassan R.M. , Abdel-Rahim M.A. , Abu-Sehly A.A. , Hafiz M.M. 
Published: July 2018

Abstract
Effect of annealing temperature on the structural and optical properties of As30Te60Ga10 thin film was studied using various techniques such as differential scanning calorimetry (DSC), X-ray diffraction (XRD) and scanning electron microscopy (SEM). The DSC analysis revealed that the As30Te60Ga10 glass has a single glass transition and crystallization peak while XRD results confirmed that the as-prepared and annealed films have crystalline nature. The coexistence of the crystalline phases in the investigated films could be attributed to the formation of orthorhombic As, hexagonal Ga7Te10, and monoclinic As2Te3 phases. It was found that the average crystallite size and optical parameters of the studied films depend on the annealing temperature. For example, the optical band gap decreased from 1.54 eV to 1.11 eV as the annealing temperature increased from 300 K to 433 K.
Crystal structure of diaqua-(N-(1-(pyrazin-2-yl)ethylidene)nicotinohydrazonato-κ3
N,N′,O)-bis(nitrato-κ2
O,O′)samarium(III), C12H14N7O9Sm
Authors: Mao Xianjie , Li Chuntong , Xu Gaoyuan , Li Huijun 
Published: July 2018

Abstract
C12H14N7O9Sm, monoclinic, P21/c (no. 14), a = 16.770(3) Å, b = 7.7185(16) Å, c = 15.165(3) Å, β = 108.409(3)°, V = 1862.5(7) Å3, Z = 4, R
gt(F) = 0.0262, wR
ref(F
2) = 0.0672, T = 296(2) K.
Crystal structure of N
2,N
4-dibutyl-6-chloro-N
2,N
4-bis(1,2,2,6,6-pentamethylpiperidin-4-yl)-1,3,5-triazine-2,4-diamine, C31H58ClN7 – Important intermediate of Chimassorb 119 synthesis
Authors: Xiao Jian , Wang Kai , Chen Qiang , Zhang Xiu-Qin , Lu Guo-Yuan 
Published: July 2018

Abstract
C31H58ClN7, monoclinic, P21/c (no. 14), a = 29.9370(18) Å, b = 15.6432(8) Å, c = 14.2792(8) Å, β = 90.819(2)°, V = 6686.4(6) Å3, Z = 8, R
gt(F) = 0.0671, wR
ref(F
2) = 0.1925, T = 173(2) K.