bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reflect and Remember: The Ethics of Complications in Interventional Radiology
Authors: Keller Eric J. 
Published: May 2019

AbstractClinicians, particularly those in procedural specialties, tend to feel personally responsible when complications occur. Medical errors among surgeons have been studied and provide an insightful window into the ethics of complications. Ethically we must consider what we owe patient and families, ourselves, and our colleagues. To some degree, the answers are similar: reflection, confession, and resolution. We owe patients and families an explanation and lack of abandonment; we owe ourselves thoughtful reflection on what caused the complication and how we can learn from it; and we owe our colleagues assistance managing our complications and a chance to learn from our mistakes. As a specialty that prides itself on innovation and novel therapies, interventional radiology has a unique relationship with complications that has not been well developed. As the specialty grows, it will be important to provide forums for further understanding the ethical challenges in interventional radiology.
Role of N-Terminal Pro-brain Natriuretic Peptide in the Early Diagnosis of Neonatal Sepsis
Authors: Okur Nilufer , Buyuktiryaki Mehmet , Uras Nurdan , Oncel Mehmet Yekta , Halil Halid , Isık Sehribanu , İpek Mehmet Sah , Canpolat Fuat Emre , Oguz Serife Suna 
Published: May 2019

Objective Sepsis is one of the most significant contributors to mortality and morbidity in the neonatal population. The need to find specific biomarkers that provide meaningful information about the diagnosis of sepsis is still ongoing. This study aimed to investigate the utility of N-terminal pro-brain natriuretic peptide (NT-proBNP) as a diagnostic biomarker in newborn infants with late-onset sepsis.
Methods A prospective, observational study was conducted in the neonatal intensive care unit between July 2016 and January 2017. The patients suspected of having late-onset sepsis and meeting the selection criteria were included in the study, and serial measurements of white blood cell count, serum C-reactive protein (CRP), plasma interleukin (IL) 6, and whole blood NT-proBNP levels were performed.
Results The study included 87 patients diagnosed with sepsis and 35 control patients. The median NT-proBNP levels were higher in septic patients (58 [22–169] vs. 14 [7–21]; p < 0.001), showing a significant correlation with CRP and IL-6 levels (r = 0.327, p < 0.01 and r = 0.216, p < 0.05, respectively). The optimal diagnostic cutoff value for differentiating sepsis was 27.5 pg/mL. Predictive parameters of NT-proBNP, such as sensitivity (72%) and specificity (86%), were comparable to those of CRP and IL-6 for the early diagnosis of sepsis in neonates.
Conclusion Plasma NT-proBNP levels were higher in septic neonates, and the predictive values were comparable to those of CRP and IL-6. However, these values were not high enough to make it a reliable diagnostic biomarker for identifying neonates in the early stages of sepsis.
Cardiogenic pulmonary edema: mechanisms and treatment - an intensivist's view
Authors: Ingbar David H. 
Published: May 2019

Purpose of review
This review summarizes current understanding of the pathophysiology of cardiogenic pulmonary edema, its causes and treatment.

Recent findings
The pathobiology and classification of pulmonary edema is more complex than the hydrostatic vs. permeability dichotomy of the past. Mechanisms of alveolar fluid clearance and factors that affect the clearance rate are under intensive study to find therapeutic strategies. Patients need early stabilization of oxygenation and ventilation, preferably with high-flow nasal cannula oxygen or noninvasive ventilation whereas the diagnostic cause is quickly sought with echocardiography and other testing.

Summary
Treatments must be initiated early, whereas evaluation still is occurring and requires multimodality intervention. The general treatment of cardiogenic pulmonary edema includes diuretics, possibly morphine and often nitrates. The appropriate use of newer approaches – such as, nesiritide, high-dose vasodilators, milrinone, and vasopressin receptor antagonists – needs larger clinical trials.
Prior Participation in Simulation Events Is Associated With Insimulation Team Performance Among Emergency Medical Services Professionals
Authors: Gurňáková Jitka , Gröpel Peter 
Published: May 2019

Introduction
Prior evidence has supported the use of high-fidelity simulation in initial emergency medical services (EMS) education, but there is a dearth of research on whether EMS professionals can also benefit from it. We sought to examine simulation use and years of practice as predictors of insimulation team performance among EMS professionals. The hypothesis is that both the prior participation in simulation events and the accumulated years of practice will predict insimulation performance.

Methods
This cross-sectional study was conducted as part of a simulation-based EMS competition. Paramedic and physician teams were tested. Participants' years of EMS and healthcare practice and their prior participation in simulation events were assessed with a survey and correlated with performance in the competition.

Results
Participants were 120 EMS professionals from 51 teams, which was 75% of all competitors. They had in average 8.03 years of healthcare practice and 5.71 years of EMS practice and had previously participated in 4.34 simulation events. The prior participation in simulation events correlated significantly with EMS insimulation performance at the team level (r = 0.40–0.59). In contrast, neither the years of healthcare practice nor the years of EMS practice significantly predicted insimulation team performance. Furthermore, there was no interaction of simulation use and years of practice.

Conclusions
The benefits of simulation use are not limited to initial EMS education but spread also to experienced professionals. Even individuals who have been working in the field for many years may benefit from high-fidelity simulation. Future research should examine whether this also translates into better clinical performance.
Levetiracetam inhibits SV2A-synaptotagmin interaction at synapses that lack SV2B
Authors: Ciruelas Kristine , Marcotulli Daniele , Sullivan Jane M , Bajjalieh Sandra M 
Published: May 2019

AbstractEpilepsy remains a difficult-to-treat neurological disorder prompting the need for new therapies that work via alternate mechanisms. Levetiracetam (LEV) is the first in a series of anti-epilepsy drugs that target presynaptic functioning. LEV binds the synaptic vesicle protein SV2A, and has been shown to decrease neurotransmitter release in hippocampal slices. The molecular basis of LEV action is unknown, however, and direct effects of LEV on SV2A function remain to be determined. SV2A is the most widely expressed paralog of a three-gene family (SV2A, B, C) that is variably co-expressed throughout the CNS. All three SV2s bind the calcium sensor protein synaptotagmin and SV2 plays a crucial role in synaptotagmin stability and trafficking. Here we addressed the action of LEV at the cellular and molecular level asking whether the presence of non-LEV binding SV2 paralogs influences drug action and whether LEV impacts SV2A’s role in synaptotagmin function. We report that LEV altered short-term synaptic plasticity in isolated neurons from SV2B knockout but not wild-type mice, mimicking the loss of SV2 function. Similarly, LEV reduced SV2A binding to synaptotagmin only in the absence of SV2B. Furthermore, LEV reduced and slowed the internalization of synaptotagmin in neurons cultured from SV2B KO but not WT mice. Taken together, these findings suggest that LEV alters synaptic release probability by disrupting SV2’s regulation of synaptotagmin selectively in neurons that express only SV2A. Neurons that meet this requirement include most inhibitory neurons and the granule cells of the dentate gyrus, two classes of neuron implicated in epilepsy.
Debbie MacInnis, autobiographical reflections
Authors: MacInnis Debbie 
Published: May 2019

Purpose
The purpose of this paper is to provide some background and context to MacInnis’ 33-year life as a marketing academic and to share some of the trials, tribulations and joys that have characterized her professional career.

Design/methodology/approach
This paper is autobiographical, highlighting some key aspects of MacInnis’ career, including the various educational, administrative, editorial, teaching and consulting roles she has held and how they have influenced her development as a scholar.

Findings
MacInnis emphasizes the importance of doing what is interesting, sticking with topics you love and working with people who inspire you and are great collaborators. We continually evolve as scholars in light of the continual changes in academic knowledge and in the world of marketing. Those changes provide exciting and enticing career opportunities.

Practical implications
Everyone should follow their own path. She has been fortunate to pursue a number of different roles in the profession, but she has learned to differentiate which activities best match who she is as an individual. Debbie would encourage others to do the same.

Social implications
We can contribute most when we understand ourselves, our strengths, our weaknesses and the other aspects of our lives that make life meaningful to us.

Originality/value
The essay offered here reflects Debbie’s path alone. Her hope is that by articulating her history, she can share with others the range of opportunities available in the field. There is no one way to succeed, and while she is not sure that her choices have made her the most successful that she could be, they are the choices she has made and she is happy to have learned both about the world and herself through these choices.
The failure to learn from others: Vertical fiscal imbalance, centralisation, and Australia's metropolitan knowledge deficit
Authors: Tomlinson Richard 
Published: May 2019

AbstractThis paper questions the routes to knowledge of metropolitan governance elsewhere in the world and then explains how and why these are rendered more difficult in Australia. The paper begins with the policy literature on the exchange of knowledge relevant to metropolitan governance. The paper next explains the constitutional and fiscal backdrop to metropolitan governance in Australia; the ‘unique’ role of state governments in the funding, planning, and management of cities, and the powers adopted by the federal government that are made possible by vertical fiscal imbalance and funding conditionality. The paper then explores horizontal knowledge exchange of metropolitan governance in the form of transnational municipal networks, corporations, international organisations, and consultants. The final section of the paper considers the thesis that were Australia's cities to function independently, as metropolitan governments, the potential for knowledge exchange would be optimised. Knowledge of smart city technologies is used for case study purposes.
Forefronts of the Sharing Economy: Uber in Cape Town
Authors: Pollio Andrea 
Published: May 2019

AbstractThe sharing economy, often phrased as ‘platform capitalism’, enables firms such as Uber and Airbnb to monetize, through specific technologies of mediation, the networks, the assets and the precarious labour of those who are described as ‘the entrepreneurs of sharing’. This article explores the urban geographies of ride‐sharing in the marketization of Uber in Cape Town, South Africa. I use empirical evidence collected during the first phase of its operations in the city, between 2013 and 2015, to show how Uber relied upon the developmental entrepreneurialism of Cape Town to embed its ride‐sharing market locally, and how the drivers enacted multiple technical, economic and ethical regimes within and without the constraints of the software platform. The research presented in this article thus contributes to understanding how the discourses of millennial development, with its promises of entrepreneurial empowerment, are adopted by global sharing‐economy firms to enact their markets in the global South. It also reveals how a different genealogy of Uber's urban transactions offers an alternative perspective on the normative rationalities of the sharing economy and on the diverse economies that exist in relation to platform capitalism in the global South.
DEveloping a Complex Intervention for DEteriorating patients using theoretical modelling (DECIDE study): Study protocol
Authors: Smith Duncan , Francis Jill J. , Aitken Leanne M. 
Published: May 2019

AbstractAimTo develop a theory‐based complex intervention (targeting nursing staff), to enhance enablers and overcome barriers to enact expected behaviour when monitoring patients and responding to abnormal vital signs that signal deterioration.DesignA mixed method design including structured observations on hospital wards, field notes, brief, unrecorded interviews and semi‐structured interviews to inform the development of an intervention to enhance practice.MethodsSemi‐structured interviews will be conducted with nursing staff using a topic guide informed by the Theoretical Domains Framework. Semi‐structured interviews will be transcribed verbatim and coded deductively into the 14 Theoretical Domains Framework domains and then inductively into “belief statements”. Priority domains will be identified and mapped to appropriate behaviour change techniques. Intervention content and mode of delivery (how behaviour change techniques are operationalized) will be developed using nominal groups, during which participants (clinicians) will rank behaviour change techniques/mode of delivery combinations according to acceptability and feasibility. Findings will be synthesised to develop an intervention manual.DiscussionDespite being a priority for clinicians, researchers and policymakers for two decades, “sub‐optimal care” of the deteriorating ward patient persists. Existing interventions have been largely educational (i.e. targeting assumed knowledge deficits) with limited evidence that they change staff behaviour. Staff behaviour when monitoring and responding to abnormal vital signs is likely influenced by a range of mediators that includes barriers and enablers.ImpactSystematically applying theory and evidence‐based methods, will result in the specification of an intervention which is more likely to result in behaviour change and can be tested empirically in future research.
Plant traits moderate pollen limitation of introduced and native plants: a phylogenetic meta‐analysis of global scale
Authors: Burns Jean H. , Bennett Joanne M. , Li Junmin , Xia Jing , Arceo‐Gómez Gerardo , Burd Martin , Burkle Laura A. , Durka Walter , Ellis Allan G. , Freitas Leandro , Rodger James G. , Vamosi Jana C. , Wolowski Marina , Ashman Tia‐Lynn , Knight Tiffany M. , Steets Janette A. 
Published: May 2019

Summary

The role of pollination in the success of invasive plants needs to be understood because invasives have substantial effects on species interactions and ecosystem functions. Previous research has shown both that reproduction of invasive plants is often pollen limited and that invasive plants can have high seed production, motivating the questions: How do invasive populations maintain reproductive success in spite of pollen limitation? What species traits moderate pollen limitation for invaders?

We conducted a phylogenetic meta‐analysis with 68 invasive, 50 introduced noninvasive and 1931 native plant populations, across 1249 species.

We found that invasive populations with generalist pollination or pollinator dependence were less pollen limited than natives, but invasives and introduced noninvasives did not differ. Invasive species produced 3× fewer ovules/flower and >250× more flowers per plant, compared with their native relatives. While these traits were negatively correlated, consistent with a tradeoff, this did not differ with invasion status.

Invasive plants that produce many flowers and have floral generalisation are able to compensate for or avoid pollen limitation, potentially helping to explain the invaders’ reproductive successes.
Region Building and Regional Cooperation in Response to Environmental Challenges: A Case Study from the Barents Region
Authors: Mackie Sarah E. 
Published: May 2019

During the Cold War, the border between Norway and the Soviet Union was almost completely closed and there were few diplomatic relations between the Arctic regions of northern Europe and the Soviet Union. Within weeks of the end of the Soviet Union, however, the Norwegian government began negotiations over regional cooperation which led to what is now the Barents Euro-Arctic Cooperation.This article argues that one of the significant incentives which led to the formation of the Barents region at the time that the Soviet Union collapsed was the common environmental threats faced by each of the Arctic nations of Europe and northwest Russia. This article considers the sources of the environmental challenges and the work that has been undertaken to tackle those shared threats. It also considers the region building that has taken place as a result of the cooperation which, although it began as a means of solving the environmental threats but has now spread much further with cohesion and cooperation in many other policy areas. The article concludes with a discussion of how this model could be used as a means of encouraging regional cooperation in other parts of the world, particularly in areas where there is a history of conflict or where there are shared environmental concerns.
The Private Scope in Public–Private Collaborations: An Institutional and Capability-Based Perspective
Authors: Quelin Bertrand V. , Cabral Sandro , Lazzarini Sergio , Kivleniece Ilze 
Published: May 2019

There has been a growing interest in the organization of business activities at the public interface as illustrated by the emergent phenomenon of public–private partnerships (PPPs). In this study, we analyze the determinants of private scope in partnering with public actors—that is, the extent to which private actors are involved in multiple, consecutive value-creating activities in the partnership. Based on a unique data set of public–private agreements worldwide over two decades, we find that institutional and capability-based determinants jointly affect the extent of private scope in public–private collaborations. Our results highlight the contingent role of the quality of the institutional environment. Institutions not only facilitate greater private scope directly but also, moderate the effect of public and private capabilities on private scope. We find that prior public experience in PPPs enhances private scope in settings with high-quality institutions while having an opposing effect in low-quality environments. Moreover, public governance capabilities accumulated via units designed to deal with PPPs seem to substitute for the lack of high-quality institutions, suggesting that, even under weak institutional settings, countries can foster high private scope with the creation of pockets of specialized public capabilities. In contrast, private capabilities in PPPs, expressed as firm engagement in recurring government cofunded projects, seem to have a complementary effect: they help to increase private scope in PPPs but only when domestic institutions are of high quality. By highlighting the determinants of private actor involvement in public sector activities, our study offers important implications for the theory and practice of hybrid (cross-sector) organizational forms. The e-companion is available at https://doi.org/10.1287/orsc.2018.1251 .
Wyzwania dla związków zawodowych w dobie bieżącego kryzysu ekonomicznego w Unii Europejskiej
Authors: Leszczyński Dariusz 
Published: May 2019

Procesy zachodzące w gospodarce państw tworzących Unię Europejską cechuje wyraźna symultaniczność, względny progres PKB odnotowywany w Europie Północnej kontrastuje z dysolucją struktur na Południu, postrzeganym zarówno poprzez pryzmat załamania gospodarki, jak i implozję niezadowolenia społecznego. Bezrobocie i towarzyszące temu zjawisku negatywne aspekty tworzą niebezpieczną bazę konfliktów, dezorganizujących i wyniszczających każde społeczeństwo. Wydarzenia te niejednokrotnie pogłębia kryzys strukturalny i instytucjonalny, szczególnie mocno identyfikowany z obszarami pozbawionymi bodźców innowacyjności, oparty na niewykorzystaniu mocy wytwórczych i braku alternatyw. Obok inwersji rozwoju gospodarczego, w mniejszym lub większym stopniu dotykającym wszystkie kraje, nie mniej ważną jest płaszczyzna relacji społecznych, która w swoim zasięgu obejmuje zagadnienia dotyczące rynku pracy i wyzwań dotyczących budowy nowego kształtu ustroju społecznego, obligując wszystkie podmioty sporu do koabitacji.
Crystal structure of 2-(naphthalen-2-yl)-1,8-naphthyridine, C18H12N2
Authors: Jia Guo-Kai , Xiu-Wen Chen , Jing-Kun Lv , Chen Xiao-Ming 
Published: May 2019

Abstract
C18H12N2, monoclinic, P21/c (no. 14), a = 27.514(5) Å, b = 6.3231(11) Å, c = 7.4175(13) Å, β = 95.805(2)°, V = 1283.8(4) Å3, Z = 4, R
gt(F) = 0.0439, wR
ref(F
2) = 0.1233, T = 296(2) K.
Crystal structure of 4-(5,5-difluoro-1,3,7,9-tetramethyl-3H,5H-5λ4-dipyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinin-10-yl)pyridin-1-ium tetraiodidoferrate(III), C18H19BF2FeI4N3
Authors: Gao Yan , Xiao Zhiyin , Zhang Peipei , Xiang Yali , Wang Wei , Hu Haimeng 
Published: May 2019

Abstract
C18H19BF2FeI4N3, triclinic, P1̄ (no. 2), a = 8.2997(3) Å, b = 11.8180(9) Å, c = 14.0849(7) Å, α = 106.388(5)°, β = 101.841(4)°, γ = 95.200(4)°, V = 1280.88(13) Å3, Z = 2, R
gt(F) = 0.0393, wR
ref(F
2) = 0.1045, T = 293(2) K.
Editorial
Authors: Díez Adriano , Consuegra Adriana 
Published: May 2019

Collectivus, Revista de Ciencias Sociales, en esta nueva publicación del volumen 5, número 2, ofrece un claro ejercicio de pensamiento y reflexión, agrupando una serie de artículos que abordan distintos aspectos de la dinámica social y cultural, en convergencia con las transformaciones sustanciales en la política, la educación, la economía, el arte y el urbanismo.AbstractCollectivus, Journal of Social Sciences, in this new publication of volume 5, number 2, offers a clear exercise of thought and reflection, grouping a series of articles that address different aspects of social and cultural dynamics, in convergence with the substantial transformations in politics, education, economy, art and urbanism.