bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protocol for developing a mental imagery intervention: a randomised controlled trial testing a novel implementation imagery e-health intervention to change driver behaviour during floods
Authors: Hamilton Kyra , Keech Jacob J , Peden Amy E , Hagger Martin S 
Published: February 2019

IntroductionDrowning due to driving into floodwater accounts for a significant proportion of all deaths by drowning. Despite awareness campaigns such as ‘If it’s flooded, forget it’, people continue to drive into floodwater. This causes loss of life, risk to rescuers and damage to vehicles. The aim of this study was to develop and evaluate an online e-health intervention to promote safe driving behaviour during flood events.Methods and analysisThe study will use a 2×3 randomised controlled trial in which participants are randomised into one of two conditions: (1) education about the risks of driving into floodwater or (2) education about the risks of driving into floodwater plus a theory-based behaviour change intervention using planning and imagery exercises. The effect of the intervention on the primary outcome, intention to drive through floodwater and the secondary outcomes will be assessed using a series of mixed-model analysis of covariances.Ethics and disseminationThe study has been approved by the Griffith University Human Research Ethics Committee. Participants will review a study information sheet and provide informed consent prior to commencing participation. Results will be disseminated through peer-reviewed publications, industry reports, media releases and at academic conferences. Deidentified data will be made publicly available following publication of the results.Trial registration numberACTRN12618001212246.
Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy
Authors: Sugawara Junichi , Ochi Daisuke , Yamashita Riu , Yamauchi Takafumi , Saigusa Daisuke , Wagata Maiko , Obara Taku , Ishikuro Mami , Tsunemoto Yoshiki , Harada Yuki , Shibata Tomoko , Mimori Takahiro , Kawashima Junko , Katsuoka Fumiki , Igarashi-Takai Takako , Ogishima Soichi , Metoki Hirohito , Hashizume Hiroaki , Fuse Nobuo , Minegishi Naoko , Koshiba Seizo , Tanabe Osamu , Kuriyama Shinichi , Kinoshita Kengo , Kure Shigeo , Yaegashi Nobuo , Yamamoto Masayuki , Hiyama Satoshi , Nagasaki Masao 
Published: February 2019

PurposeA prospective cohort study for pregnant women, the Maternity Log study, was designed to construct a time-course high-resolution reference catalogue of bioinformatic data in pregnancy and explore the associations between genomic and environmental factors and the onset of pregnancy complications, such as hypertensive disorders of pregnancy, gestational diabetes mellitus and preterm labour, using continuous lifestyle monitoring combined with multiomics data on the genome, transcriptome, proteome, metabolome and microbiome.ParticipantsPregnant women were recruited at the timing of first routine antenatal visits at Tohoku University Hospital, Sendai, Japan, between September 2015 and November 2016. Of the eligible women who were invited, 65.4% agreed to participate, and a total of 302 women were enrolled. The inclusion criteria were age ≥20 years and the ability to access the internet using a smartphone in the Japanese language.Findings to dateStudy participants uploaded daily general health information including quality of sleep, condition of bowel movements and the presence of nausea, pain and uterine contractions. Participants also collected physiological data, such as body weight, blood pressure, heart rate and body temperature, using multiple home healthcare devices. The mean upload rate for each lifelog item was ranging from 67.4% (fetal movement) to 85.3% (physical activity), and the total number of data points was over 6 million. Biospecimens, including maternal plasma, serum, urine, saliva, dental plaque and cord blood, were collected for multiomics analysis.Future plansLifelog and multiomics data will be used to construct a time-course high-resolution reference catalogue of pregnancy. The reference catalogue will allow us to discover relationships among multidimensional phenotypes and novel risk markers in pregnancy for the future personalised early prediction of pregnancy complications.
Intracoronary near-infrared spectroscopy and the risk of future cardiovascular events
Authors: Karlsson Sofia , Anesäter Erik , Fransson Klara , Andell Pontus , Persson Jonas , Erlinge David 
Published: February 2019

ObjectivesThe objectives of this study were to investigate if findings by intracoronary near-infrared spectroscopy (NIRS) and intravascular ultrasound (IVUS) are associated with future cardiovascular events and if NIRS can differentiate culprit from non-culprit segments in patients with coronary artery disease.MethodsThe study included 144 patients with coronary artery disease undergoing percutaneous coronary intervention and combined NIRS-IVUS imaging at two Swedish hospitals. The NIRS-derived lipid core burden index (LCBI), the 4 mm segment with maximum LCBI (MaxLCBI4mm) and the IVUS-derived maximum plaque burden (MaxPB) were analysed within the culprit segment and continuous 10 mm non-culprit segments of the index culprit vessels. The association with future major adverse cardiovascular and cerebrovascular events (MACCE), defined as all-cause mortality, acute coronary syndrome requiring revascularisation and cerebrovascular events during follow-up was evaluated using multivariable Cox regressions. A receiver operating characteristic (ROC) analysis was performed to test the ability of NIRS to discriminate culprit against non-culprit segments.ResultsA non-culprit maxLCBI4mm≥400 (HR: 3.67, 95% CI 1.46 to 9.23, p=0.006) and a non-culprit LCBI ≥ median (HR: 3.08, 95% CI 1.11 to 8.56, p=0.031) were both significantly associated with MACCE, whereas a non-culprit MaxPB ≥70% (HR: 0.61, 95% CI 0.08 to 4.59, p=0.63) was not. The culprit segments had larger lipid cores compared with non-culprit segments (MaxLCBI4mm425 vs 74, p<0.001), and the ROC analysis showed that NIRS can differentiate culprit against non-culprit segments (c-statistics: 0.85, 95% CI 0.81 to 0.89).ConclusionA maxLCBI4mm≥400 and LCBI ≥ median, assessed by NIRS in non-culprit segments of a culprit artery, were significantly associated with patient-level MACCE. NIRS furthermore adequately discriminated culprit against non-culprit segments in patients with coronary disease.
Complications and prognosis of patients undergoing apical or septal right ventricular pacing
Authors: Spath Nick B , Wang Kelvin , Venkatasumbramanian Sowmya , Fersia Omar , Newby David E , Lang Chris CE , Grubb Neil R , Dweck Marc R 
Published: February 2019

ObjectivesOptimal right ventricular lead placement remains controversial. Large studies investigating the safety and long-term prognosis of apical and septal right ventricular lead placement have been lacking.MethodsConsecutive patients undergoing pacemaker insertion for high-degree atrioventricular block at Edinburgh Heart Centre were investigated. Periprocedural 30-day complications were defined (infection/bleeding/pneumothorax/tamponade/lead displacement). Long-term clinical outcomes were obtained from the General Register of Scotland and electronic medical records. The primary endpoint was a composite of all-cause mortality, new heart failure, hospitalisation for a major cardiovascular event, as per theCArdiacREsynchronization inHeartFailure trial. Secondary endpoints were all-cause mortality, new heart failure and their composite.Results820 patients were included, 204 (25%) paced from the septum and 616 (75%) from the apex. All baseline variables were similar with the exception of age (septal: 73.2±1.1 vs apical: 76.9±0.5 years, p<0.001). Procedure duration (58±23 vs 55±25 min, p=0.3), complication rates (18 (8.8) vs 46 (7.5)%, p=0.5) and postimplant QRS duration (152 (23) vs 154 (27) ms, p=0.4) were similar. After 1041 days (IQR 564), 278 patients met the primary endpoint, with no difference between the septal and apical groups in unadjusted (HR 0.86 (95% CIs 0.64 to 1.15)) or multivariable analysis correcting for age, gender and comorbidity (HR 0.97 (95% CI 0.72 to 1.30)). Similarly, no differences were observed in the secondary endpoints.ConclusionsThis large real-world cohort of patients undergoing right ventricular lead placement in the septum or apex demonstrated no difference in procedural complications nor long-term clinical outcomes. Both pacing strategies appear reasonable in routine practice.
Cost Analysis of a Multidisciplinary Vascular Anomaly Clinic
Authors: Straughan Alexander J. , Mudd Pamela A. , Silva Allison L. , Callicott Susan S. , Krakovsky Gina , Bauman Nancy M. 
Published: February 2019

Objective: Multidisciplinary vascular anomaly clinics (VACs) offer important value to pediatric patients with complex vascular anomalies whose care overlaps specialties. These clinics are labor intensive and costly to operate since providers see fewer patients compared to their individual specialty clinic. Our North American tertiary care institution’s VAC specialists include a pediatric otolaryngologist, pediatric surgeon, pediatric plastic surgeon, pediatric dermatologist, and interventional radiologist. To assess financial feasibility, we conducted a cost analysis of our VACs comprised of 2 half-day multidisciplinary physician attended clinics (5 specialists at our main campus and 2 specialists at a satellite clinic) and a half-day nurse practitioner clinic. Method: Assessment of net revenue based on net collections for clinic, professional, operative, hospital setting, and facility charges generated during 12 consecutive monthly VACs beginning July 1, 2015. Expense calculations included provider and staff salaries, benefits, supply costs, and clinic leasing costs. Results: There were 469 clinic visits, of which 202 were new patient evaluations. Sixty-eight patients underwent 93 procedures under general anesthesia, including procedures performed by our interventional radiologist, most commonly sclerotherapy or embolization (n = 37), surgical interventions including endoscopy (n = 36), or laser procedures (n = 20). Three patients were admitted. Fifty-seven patients received a new diagnosis different from that for which they were referred. Gross revenue was $1 810 525, and net revenue was 42.5%, or $783 152. Expenses totaled $453 415 for a net positive revenue of $329 737. Conclusion: When including direct downstream revenue, particularly from operative procedures, our VAC program operates on a net positive margin, making the program financially feasible.
Drawing into being: The trap as a diagram for ecological exchange between art and anthropology
Authors: Spriggs Hermione 
Published: February 2019

This article aims to further Alfred Gell’s assertion (‘Vogel’s net: Traps as artworks and artworks as traps’, Journal of Material Culture, 1996) that traps be considered as functional artworks and vice versa, and builds on this foundation for an even bolder approach to practical exchange between art and anthropology. The trap is explored as a particular kind of technology that enables analytical play between species perspectives and disciplines which might at first appear to be ontologically distinct from one another, but are in fact recursively shaped and shape one another. Particular emphasis is placed on the ‘craftiness’ of animal traps as adaptable structures with a playful (if combative) propensity, by way of parallel examples of artistic forms and engagements that are ‘tricky’ in relation to existing norms of consumption and production – or even in regards to the label of Art itself. Gell’s initial comparison is used as a means by which traps and artworks might bear more integrally upon one another to suggest not only certain structural similarities (as Gell suggested), but further co-generative potential for new frames of anthropological engagement and more-than-human artistic production. The trap emerges as a ‘diagram of practice’ that enables visual art to locate itself in an ecologically recursive relationship with a given environment. Just as Gell suggested, the trap takes art beyond existing art-historical frameworks and aesthetic conventions. As a method for anthropology, trapping suggests an experimental approach to fieldwork that adopts unconventional media from a given context to playfully draw from its more-than-human object of study. It is for both art and anthropology alike to conjure up the question – like a well-set trap – what is it like to ‘be’ and draw into being that which one is not?
Using Artistic Expression as a Teaching Strategy for Social Justice: Examining Music From the Civil Rights and Black Lives Matter Movements
Authors: Bohonos Jeremy W. , Otchere Kimberly D. , Pak Yoon 
Published: February 2019

The Problem Members of organizations often struggle to grasp the importance of social movements and to understand the affective dimensions of the injustices that inspire them to be organized. The Solution We argued that combining artistic expression with social movement learning (SML) in human resource development (HRD) can help members of the dominant culture to better empathize with those who experience marginalization. This will help organizations to better relate to social movements and to more effectively address related injustices. The Stakeholders HRD scholars and practitioners as well as those engaged in social movements.
Against the Bildungsroman
Authors: Duncan Ian 
Published: February 2019

AbstractTrained on the history of the novel in English, Nancy Armstrong’s Desire and Domestic Fiction also illuminates continental European developments. Wilhelm Meister’s Apprenticeship, the prototype of the nineteenth-century “novel of development” (bildungsroman), forms itself against domestic fiction and its core principle, that, in Armstrong’s words, “the modern individual was first and foremost a woman.” Goethe’s novel elects a male protagonist as the universal subject of a modern developmental logic of human nature and articulates his progress on a succession of sacrificial stages occupied by the story’s women. In a militant response, Germaine de Staël’s Corinne refeminizes the novelistic protagonist, investing the role with the developmental imperative of Bildung and the claim on universal human representativeness, realized through the heroine’s artistic vocation. Corinne, however, falls into a conventional love story and is sacrificed to a marriage plot, which here and elsewhere Staël identifies with the distinctively English genre of domestic fiction. Refusing to naturalize the arrangements analyzed in Desire and Domestic Fiction from its position outside the English tradition, Corinne shows that the hegemony of domestic realism was neither absolute nor inevitable.
Social, Sexual, and Other Contracts in Eighteenth-Century Novels
Authors: Lynch Deidre 
Published: February 2019

Abstract
This essay highlights the role that Enlightenment conjectural histories and liberal concepts of contractual exchange play in Nancy Armstrong’s revisionist description of the rise of the novel. It urges scholars of the novel to follow the example of Desire and Domestic Fiction and remember more often the eighteenth-century narrative experiments that unfolded when liberalism was still new. Eliza Haywood’s novel of amorous (and sapphic) intrigue The British Recluse (1722) suggests one reason to do that remembering. To see how Haywood uses the figure of the contract—very differently from Samuel Richardson and Jane Austen—is to better apprehend how in the early eighteenth century the marriage plot’s ideal of heterosexual complementarity had not yet become the only game in town.
„Gong Głodomora” – humorystyczny obraz atmosfery intelektualnej i obyczajowości panującej w Zakładzie Przyrodoleczniczym doktora Apolinarego Tarnawskiego w Kosowie
Authors: Tarkowska Natalia 
Published: February 2019

Starveling’s Gong. A Humorous Portrayal of the Intellectual Atmosphere and Customs of the Natural Medicine Centre of Dr Apolinary Tarnawski in KosowStarveling’s Gong is a unique copy of a satirical piece in the form of a typewritten journal edited by the patients of the Natural Medicine Centre of Dr Apolinary Tarnawski in Kosow in Pokkuttya. The Natural Medicine Centre was located on the territory of the former Stanisławow Voivodeship (currently Ivano-Frankivsk Oblast, Ukraine). The centre , active in 1893-1939, was one of backbone of Polish cultural life in the Borderlands. As a popular holiday destination for the intelligentsia, it became an ideal platform for stimulating literary and artistic creativity. The preserved text was created by prominent writers, poets and artists, such as: Kazimierz Wierzyński, Wit Tarnawski, Stefan Norblin, Alina Kwiecińska, Wiktor Podoski, Wojciech Zaleski or prof. Ignacy Chrzanowski, who all stayed in Kosow for treatment in the summer of 1937. From the edited manuscript provides a vivid image of the Polish intellectual activity in the 1930s. In addition, the text brings us closer to fuller knowledge about what entertainment the elite provided themselves during the stay in health resorts. The retrieved manuscript undoubtedly inspires further research into the intellectual contribution and cultural achievements of the medical centre in Kosow for the development of the native culture.
Z Mościsk do Jugowa - relacje Józefy Wójcik i Marii Kocur repatriantek z Kresów Wschodnich
Authors: Więch Arkadiusz S. 
Published: February 2019

From Mościska to Jugów. Testimonies of Józefa Wójcik and Maria Kocur, repatriates from the Eastern Polish BorderlandsThe history of the inhabitants of the former Polish Eastern Borderlands is an interesting research topic, especially when connected to everyday life issues. Oral testimonies are important historical sources which help explore the subject better. This paper presents transcriptions of two conversations with sisters Józefa Wójcik (born in 1930) and Maria Kocór (born in 1928). Both of them were born and spent their prime years around Mościska near Lviv, and after World War II were re-settled to Jugów in Lower Silesia. The interviews were conducted in 2014 as part of a research project in the field of oral history entitled “Everyday life of inhabitants of the Owl Mountains in 1945-1970”.
Social and Institutional Construction of Regional Borders in the Western and Northern Lands – on the example of Żuławy and Powiśle
Authors: Paprot-Wielopolska Aleksandra 
Published: February 2019

This article discusses the creation of contemporary regional borders in the Western and Northern Lands, which were incorporated into Poland after the Second World War. Using the example of Żuławy and Powiśle, the author presents an anthropological analysis of the social, cultural, and administrative developments in the region, as well as the effect of those changes on the perception of these areas by their current inhabitants. Hence, she describes the strategies used to legitimise the borders of Żuławy and Powiśle by the local communities and institutions. The author discusses different approaches to the notion of regional borders, and their relation to historical, cultural, geographic and administrative borders. She further analyses the emergence of regional borderlands, centres, and peripheries. Data regarding the borders of Żuławy and Powiśle has been collected using mixed methods research. Both qualitative research methods (conceptual maps, targeted in‑depth interviews conducted among leaders and representatives of institutions) and quantitative research methods (questionnaires conducted opposition, i.e. the factor that influences its power of action. This paper presents these problems together with certain methods of solving them used in the studies conducted. It was concluded that studies in the subject of opposition require various methods and different research perspectives, including behaviourism and interpretationism.
Fecal Microbiota Transplantation in Patients With Primary Sclerosing Cholangitis: A Pilot Clinical Trial
Authors: Allegretti Jessica R. , Kassam Zain , Carrellas Madeline , Mullish Benjamin H. , Marchesi Julian R. , Pechlivanis Alexandros , Smith Mark , Gerardin Ylaine , Timberlake Sonia , Pratt Daniel S. , Korzenik Joshua R. 
Published: February 2019

BACKGROUND:
Primary sclerosing cholangitis (PSC) is a cholestatic liver disease with no effective medical therapies. A perturbation of the gut microbiota has been described in association with PSC, and fecal microbiota transplantation (FMT) has been reported to restore the microbiome in other disease states. Accordingly, we aimed at evaluating the safety, change in liver enzymes, microbiota, and metabolomic profiles in patients with PSC after FMT.

METHODS:
An open-label pilot study of patients with PSC with concurrent inflammatory bowel disease and alkaline phosphatase (ALP) > 1.5× the upper limit of normal was conducted. The patients underwent a single FMT by colonoscopy. Liver enzyme profiles and stool microbiome and metabolomic analysis were conducted at baseline and weeks 1, 4, 8, 12, and 24 post-FMT. The primary outcome was safety, and the secondary outcome was a decrease in ALP levels ≥50% from baseline by week 24 post-FMT; stool microbiota (by 16S rRNA gene profiling) and metabonomic dynamics were assessed.

RESULTS:
Ten patients underwent FMT. Nine patients had ulcerative colitis, and 1 had Crohn's colitis. The mean baseline ALP level was 489 U/L. There were no related adverse events. Overall, 30% (3/10) experienced a ≥50% decrease in ALP levels. The diversity increased in all patients post-FMT, as early as week 1 (P < 0.01). Importantly, abundance of engrafter operational taxonomic units in patients post-FMT correlated with decreased ALP levels (P = 0.02).

DISCUSSION:
To our knowledge, this is the first study to demonstrate that FMT in PSC is safe. In addition, increases in bacterial diversity and engraftment may correlate with an improvement in ALP among patients with PSC.
Sex Hormone–Binding Globulin Levels in Young Men Are Associated With Nonalcoholic Fatty Liver Disease in Midlife
Authors: Sarkar Monika , VanWagner Lisa B. , Terry James G. , Carr J. Jeffrey , Rinella Mary , Schreiner Pamela J. , Lewis Cora E. , Terrault Norah ,   for the Coronary Artery Risk Development in Young Adults (CARDIA) Cohort
Published: February 2019

INTRODUCTION:
Cross-sectional data note lower levels of testosterone and sex hormone–binding globulin (SHBG) levels in men with nonalcoholic fatty liver disease (NAFLD). Whether sex hormone levels in young men are predictive of later risk of NAFLD is not known.

METHODS:
Among men in the prospective population-based multicenter Coronary Artery Risk Development in Young Adults study (mean age 50; n = 837), we assessed whether testosterone and SHBG levels measured at study year 10 (median age 35 years) were associated with prevalent NAFLD at study year 25. NAFLD was defined using noncontrast abdominal computed tomography (CT) scan after excluding other causes of hepatic steatosis. The association of testosterone and SHBG with prevalent NAFLD was assessed by logistic regression.

RESULTS:
Total testosterone levels in young men were inversely associated with subsequent prevalent NAFLD on unadjusted analysis (odds ratio [OR] 0.64, 95% confidence interval 0.53–0.7, P < 0.001), although no longer significant after adjustment for year 10 metabolic covariates as well as change in metabolic covariates from years 10 to 25 (OR 0.99, 95% confidence interval 0.76–1.27). In contrast, there was a significant inverse association of SHBG with prevalent NAFLD, independent of testosterone and metabolic covariates (OR 0.68, OR 0.51–0.92, P = 0.013). On formal mediation testing, visceral adiposity was found to explain ∼41.0% (95% confidence interval 27%–73%) of the association of lower SHBG with prevalent NAFLD.

CONCLUSIONS:
Lower levels of SHBG in young men are associated with increase in prevalent NAFLD in middle age, independent of comprehensive metabolic risk factors. SHBG may provide a novel marker of NAFLD risk in young men.