bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimum design of hydraulic water retaining structures incorporating uncertainty in estimating heterogeneous hydraulic conductivity utilizing stochastic ensemble surrogate models within a multi-objective multi-realisation optimisation model
Authors: Al-Juboori Muqdad , Datta Bithin 
Published: December 2018

AbstractIn order to find optimum and reliable designs for hydraulic water retaining structures (HWRSs), a reliability based optimum design (RBOD) model was used to quantify uncertainty in estimates of seepage characteristics due to uncertainty in heterogeneous hydraulic conductivity (HHC). This included incorporating reliability measures into minimum-cost HWRS designs and utilising a multi-realisation optimisation technique based on various stochastic ensemble surrogate models. To improve the efficiency of the RBOD model and the direct search optimisation solver, a multi-objective multi-realisation optimisation (MOMRO) model was employed. Some of the stochastic optimisation constraints could be formulated as a second objective function to be minimised in the MOMRO model. This can significantly improve the search efficiency of the multi-objective non-dominated sorting genetic algorithm-II (NSGA-II) that was used, and help determine more feasible candidate solutions in the search space. Gaussian process regression was used to develop the surrogate models, which were trained on numerous datasets created from numerical seepage simulations. The effect of uncertainty was also considered for other HWRS safety factors and conditions, such as overturning, flotation, sliding and eccentric loading. The results demonstrate that uncertainty in HHC estimates significantly impacts optimum HWRS design. Therefore, deterministic optimum solutions that are created based on expected values of hydraulic conductivity are not adequate for reliable HWRS design. The developed MOMRO model, which was based on an ensemble approach, addresses some of the uncertainty in HHC values that affects HWRS design. Also, the MOMRO technique improves the efficiency of the optimisation search process and facilitates a direct search process to provide many optimum alternatives.Highlights The uncertainty in HHC affects the optimum HWRS design. MOMR is used to quantify the reliability based on stochastic ensemble surrogate models. The MOMR technique improves the direct search optimization process based NSGA-II. Exit gradient is influenced by the uncertainty of HHC and affects the HWRS optimum designs.
Exacerbation causes among inflammatory bowel disease patients in Guilan Province north of Iran
Authors: Hosseini Raheleh Sadat , Mansour-Ghanaei Fariborz , Shafaghi Afshin , Hojati Amineh , Joukar Farahnaz , Roushan Zahra Atrkar , Hosseini Fakhri Alsadat , Mavaddati Sara 
Published: December 2018

Abstract
Objective Numerous factors may contribute as triggers to the exacerbation of the condition of patients with inflammatory bowel disease.
Methods The medical files of 109 patients with the positive history of inflammatory bowel disease exacerbation between March 2016 and March 2017 were assessed retrospectively. Data were obtained using the inflammatory bowel disease data bank software. The parameters were obtained from the inflammatory bowel disease data bank software. The mentioned parameters were assessed in terms of type and severity of disease using chi-square test in SPSS software. Moreover, binary logistic regression test was used to assess the associations between season of disease onset and inflammatory bowel disease exacerbation as odds ratios with 95% confidence intervals (95% CI).
Results Overall, (88.1%) of cases with inflammatory bowel disease exacerbation, had ulcerative colitis. The mean age of patients was 38.14 ± 14.66 years. The disease duration in all patients (ulcerative colitis and Crohn's disease) was 35.43 and 38.85 months, respectively. About 50% of patients with infection were strongyloides stercoralis positive. The occurrence of mild inflammatory bowel disease exacerbation was significantly higher in spring in comparison to other seasons (OR = 3.58; 95% CI 0.1–1.04). Most patients with ulcerative colitis were prescribed salicylates alone (53.12%). Most patients with Crohn's disease with mild and severe activity were non-smokers (p = 0.058). This difference was marginally significant.
Conclusion It is suggested that in future studies, the evidences of distribution of SS infections among patients with inflammatory bowel disease and the history of exacerbation along with other environmental factors such as enhancing nutritional quality and surface water be taken into consideration.
DISEMBODIMENT: REPRODUCTION, TRANSCRIPTION, AND TRACE
Authors: Einbond Aaron 
Published: December 2018

AbstractThis article poses the question, what is so great about the body? Recent scholarship has emphasized the concept of an embodied cognition and reminded us of the significance of embodiment in musical performance. Yet, vital as these observations may be, they offer only a limited view of what ‘touch’ can mean. Following the semiotic notion of the index as a sign with a real connection to its object, writers and artists such as Friedrich Kittler, Ai Weiwei, Kenneth Goldsmith and Nicolas Donin have reflected on how the reproductions of the gramophone needle, the calligrapher's brush, the blogger's keyboard, and the programmer's code can trace meaningful points of contact. Examples from my own practice illustrate some of the many possible ways that digital traces can be touching.
ZUHANDEN
Authors: Molitor Claudia 
Published: December 2018

AbstractAs a pianist I spent many hours practising the connection between my touching and my listening, adjusting the pressure and weight of touching the keyboard to elicit just the right sonic texture in a note. As a composer I have spent years exploring the connection between my embodied act of notating and its potential sonic reality. Both these endeavours are acts of honing cross-modal activity. As I continue to qualify my experiences of sound and working with sound through language in instances like this – writing about my practice – I find myself constructing an increasingly complex and expanding web of linguistic gymnastics, in an attempt to explain, explore and grasp the slippery subject of listening.
Global Varieties of Capitalism
Authors: Feldmann Magnus 
Published: December 2018

AbstractThis article analyzes the prospects for globalizing the varieties of capitalism (voc) debate. It identifies and compares firm-centered, governance-centered, and state-centered approaches to extending the debate on capitalist diversity, and discusses the distinctive contributions of each approach as well as the trade-offs between them. The author draws on three agenda-setting volumes that engage with thevocframework and study capitalist diversity in three regions not usually covered by this literature: Latin America, East and Southeast Asia, and East Central Europe. As these regions play an increasingly important role in the world economy, this article examines what the books imply about the current state of knowledge about globalvoc. The author argues that the extension of thevocdebate to these parts of the world is important for advancing the understanding of economic institutions; the approach can reinvigorate research on capitalist diversity and the institutional foundations of economic development in the current era of globalization.
Smart Navigation of Humanoid Robots Using DAYKUN-BIP Virtual Target Displacement and Petri-Net Strategy
Authors: Parhi Dayal R. , Kumar Priyadarshi Biplab 
Published: December 2018

SummaryWith an ability to mimic the human behaviour and replace human efforts in proper platforms, humanoid robots have always acquired a special place among robotics practitioners. Being a complex method of analysis, navigation and path planning, humanoid robots still possess an interesting yet challenging area of investigation. In the current work, a novel navigational strategy has been proposed for smooth and hassle-free movement of single as well as multi-humanoid robots in complex environments. Here, the navigational plan is based on a virtual target displacement strategy which is activated when the robot is unable to find a safe path along the actual target line. After detection of a potential obstacle by the sensors of the robot, a number of virtual targets are generated around the actual target. Then, the most feasible path and point to move are calculated by assigning suitable weightage through several selected parameters to each target line and visualizing the safest path. The proposed approach is implemented on a V-REP simulation platform, and the simulation results are also validated against an experimental set-up prepared under test conditions. The validation of simulation results against experimental counterparts has revealed satisfactory agreement between them. To avoid possibility of any inter-collision during navigation of multi-humanoids under a common platform, a Petri-Net strategy has been integrated along with the proposed control strategy. Finally, the developed approach is also assessed against another existing navigational controller, and a significant performance improvement has been observed.
miR-23a promotes invasion of glioblastoma via HOXD10-regulated glial-mesenchymal transition
Authors: Yachi Kazuhiro , Tsuda Masumi , Kohsaka Shinji , Wang Lei , Oda Yoshitaka , Tanikawa Satoshi , Ohba Yusuke , Tanaka Shinya 
Published: December 2018

AbstractGlioblastoma is the most aggressive and invasive brain tumor and has a poor prognosis; elucidating the underlying molecular mechanisms is essential to select molecular targeted therapies. Here, we investigated the effect of microRNAs on the marked invasiveness of glioblastoma. U373 glioblastoma cells were infected with 140 different microRNAs from an OncomiR library, and the effects of the invasion-related microRNAs and targeted molecules were investigated after repeated Matrigel invasion assays. Screening of the OncomiR library identified miR-23a as a key regulator of glioblastoma invasion. In six glioblastoma cell lines, a positive correlation was detected between the expression levels of miR-23a and invasiveness. A luciferase reporter assay demonstrated that homeobox D10 (HOXD10) was a miR-23a-target molecule, which was verified by high scores from both the PicTar and miRanda algorithms. Forced expression of miR-23a induced expression of invasion-related molecules, including uPAR, RhoA, and RhoC, and altered expression of glial-mesenchymal transition markers such as Snail, Slug, MMP2, MMP9, MMP14, and E-cadherin; however, these changes in expression levels were reversed by HOXD10 overexpression. Thus, miR-23a significantly promoted invasion of glioblastoma cells with polarized formation of focal adhesions, while exogenous HOXD10 overexpression reversed these phenomena. Here, we identify miR-23a-regulated HOXD10 as a pivotal regulator of invasion in glioblastoma, providing a novel mechanism for the aggressive invasiveness of this tumor and providing insight into potential therapeutic targets.
CI Camelopardalis: The first sgB[e]-high mass X-ray binary twenty years on: A supernova imposter in our own Galaxy?
Authors: Bartlett E. S. , Clark J. S. , Negueruela I. 
Published: December 2018

Context. The Galactic supergiant B[e] star CI Camelopardalis (CI Cam) was the first sgB[e] star detected during an X-ray outburst. The star brightened to ∼2 Crab in the X-ray regime (∼5 × 10−8 ergs cm−2 s−1 in the 2–25 keV range) within hours before decaying to a quiescent level in less than two weeks, clearly indicative of binarity. Since the outburst of CI Cam, several sgB[e] stars have been identified as X-ray overluminous for a single star (i.e. LX >  10−7 Lbol). This small population has recently expanded to include two ultra luminous X-ray sources (ULX), Holmberg II X-1 and NGC 300 ULX-1/supernova imposter SN2010da.
Aims. Since the discovery of X-ray emission from CI Cam, there have been many developments in the field of massive binary evolution. In light of the recent inclusion of two ULXs in the population of X-ray bright sgB[e] stars, we revisit CI Cam to investigate its behaviour over several timescales and shed further light on the nature of the compact object in the system, its X-ray outburst in 1998 and the binary system parameters.
Methods. We analysed archival XMM-Newton EPIC-pn spectra and light curves along with new data from Swift and NuSTAR. We also present high-resolution (R ∼ 85 000) Mercator/HERMES optical spectra, including a spectrum taken 1.02 days after our NuSTAR observation.
Results. Despite being in quiescence, CI Cam is highly X-ray variable on timescales of days, both in terms of total integrated flux and spectral shape. We interpret these variations by invoking the presence of an accreting compact companion immersed in a dense, highly structured, aspherical circumstellar envelope. The differences in the accretion flux and circumstellar extinction represent either changes in this environment, triggered by variable mass loss from the star, or the local conditions to the accretor due to its orbital motion. We find no evidence for pulsations in the X-ray light curve.
Conclusions. CI Cam has many similarities with SN2010da across mid-IR, optical and X-ray wavelengths suggesting that, subject to distance determination for CI Cam, if CI Cam was located in an external galaxy its 1998 outburst would have led to a classification as a supernova imposter.
Transform your human resources processes to improve your patient’s care, quality, and results
Authors: Boukhobza A. , Etchebarne T. 
Published: December 2018

The purpose of this article is to identify what are the human resources processes to be implemented in orthodontic practices to both improve the management of patients, but also the profitability of the structure in terms of both organization and financial.
The work on the cohesion of the teams will create a collective commitment which depends on the one hand on the quality of the recruitment of the employees, and then on the motivation levers set up within the teams and maintained over time. In the teams the intergenerational collaboration must be managed and optimized.
On the other hand, the orthodontist leader must have a clear strategy and clear objectives to be able to communicate effectively. He must also know the communication tools according to the circumstances to convey the messages he needs.
Cutoff Points, Sensitivities, and Specificities of Intraoperative Motor-Evoked Potential Monitoring Determined Using Receiver Operating Characteristic Analysis
Authors: Akimoto Jiro , Hashimoto Ryo , Takanashi Junko , Oka Hidehiro , Tanaka Satoshi 
Published: December 2018

Background Although intraoperative motor-evoked potential (MEP) monitoring is widely performed during neurosurgical operations, evaluating its results is controversial.
Study Aims The cutoff point of MEP monitoring should be determined not only to predict but also to prevent postoperative neurologic deficits.
Material and Methods MEP monitoring was performed during 484 neurosurgical operations for patients without definitive preoperative motor palsy including 325 spinal operations, 102 cerebral aneurysmal operations, and 57 brain tumor operations, all monitored by transcranial stimulation, and 34 brain tumor operations monitored under direct cortical stimulation. To exclude the effects of muscle relaxants on MEP, the compound muscle action potential (CMAP), measured immediately after transcranial stimulation or direct cortical stimulation at supramaximal stimulation of the peripheral nerve, was used for normalization. The cutoff points, sensitivity, and specificity of MEP recorded during neurosurgery were examined by receiver operating characteristic (ROC) analyses and categorized according to the type of operation and stimulation.
Results In spinal operations under transcranial stimulation, amplitude reduction of 77.9% and 80.6% as cutoff points for motor palsy with and without CMAP normalization, respectively, provided a sensitivity of 100% and specificity of 96.8% and 96.5%. In aneurysmal operations under transcranial stimulation, cutoff points of 70.7% and 69.6% offered specificities of 95.2% and 95.7% with and without CMAP normalization, respectively. The sensitivities for both were 100%. In brain tumor operations under direct stimulation, cutoff points were 83.5% and 86.3% with or without CMAP normalization, respectively, and the sensitivity and specificity for both were 100%.
Conclusion An amplitude decrease of 80% in brain tumor operations, 75% in spinal operations, and 70% in aneurysmal operations should be used as the cutoff points.
Asymptotic bounds for spherical codes
Authors: Manin Yu. I. , Marcolli M. 
Published: December 2018

Abstract
The set of all error-correcting codes

over a fixed finite alphabet

of cardinality

determines the set of code points in the unit square

with coordinates

:= (relative transmission rate, relative minimal distance). The central problem of the theory of such codes consists in maximising simultaneously the transmission rate of the code and the relative minimum Hamming distance between two different code words. The classical approach to this problem explored in vast literature consists in inventing explicit constructions of “good codes” and comparing new classes of codes with earlier ones.
A less classical approach studies the geometry of the whole set of code points

(with

fixed), at first independently of its computability properties, and only afterwards turning to problems of computability, analogies with statistical physics, and so on.
The main purpose of this article consists in extending this latter strategy to the domain of spherical codes.
Division by

on odd-degree hyperelliptic curves and their Jacobians
Authors: Zarhin Yu. G. 
Published: December 2018

Abstract
Let

be an algebraically closed field of characteristic different from

,

a positive integer,

a polynomial of degree

with coefficients in

and without multiple roots,

the corresponding hyperelliptic curve of genus

over

, and

its Jacobian. We identify

with the image of its canonical embedding in

(the infinite point of

goes to the identity element of

). It is well known that for every

there are exactly

elements

such that

. Stoll constructed an algorithm that provides the Mumford representations of all such

in terms of the Mumford representation of

. The aim of this paper is to give explicit formulae for the Mumford representations of all such

in terms of the coordinates

, where

is given by a point

. We also prove that if

, then

does not contain torsion points of orders between

and

.
Birationally rigid complete intersections of high codimension
Authors: Evans D. , Pukhlikov A. V. 
Published: December 2018

Abstract
We prove that a Fano complete intersection of codimension

and index

in the complex projective space

for

and

with at most multi-quadratic singularities is birationally superrigid. The codimension of the complement of the set of birationally superrigid complete intersections in the natural moduli space is shown to be at least

. The proof is based on the technique of hypertangent divisors combined with the recently discovered

-inequality for complete intersection singularities.
Conformally invariant inequalities in domains in Euclidean space
Authors: Avkhadiev F. G. 
Published: December 2018

Abstract
We study conformally invariant integral inequalities for real-valued functions defined on domains

in

-dimensional Euclidean space. The domains considered are of hyperbolic type, that is, they admit a hyperbolic radius

satisfying the Liouville non-linear differential equation and vanishing on the boundary of the domain. We prove several inequalities which hold for all smooth compactly supported functions

defined on a given domain of hyperbolic type. Here are two of them:

where

,

and

. We also study the relations between Euclidean and hyperbolic characteristics of domains.
Nice triples and moving lemmas for motivic spaces
Authors: Panin I. A. 
Published: December 2018

Abstract
This paper contains geometric tools developed to solve the finite-field case of the Grothendieck–Serre conjecture in [1]. It turns out that the same machinery can be applied to solve some cohomological questions.
In particular, for any presheaf of

-spectra

on the category of

-smooth schemes, all its Nisnevich sheaves of

-stable homotopy groups are strictly homotopy invariant. This shows that

is

-local if and only if all its Nisnevich sheaves of ordinary stable homotopy groups are strictly homotopy invariant. The latter result was obtained by Morel [2] in the case when the field

is infinite.
However, when

is finite, Morel’s proof does not work since it uses Gabber’s presentation lemma and there is no published proof of that lemma. We do not use Gabber’s presentation lemma. Instead, we develop the machinery of nice triples invented in [3]. This machinery is inspired by Voevodsky’s technique of standard triples [4].
On accumulation points of volumes of log surfaces
Authors: Alexeev V. A. , Liu W. 
Published: December 2018

Abstract
Let

be a set satisfying the descending chain condition. We show that every accumulation point of volumes of log canonical surfaces

with coefficients in

can be realized as the volume of a log canonical surface with big and nef

and with coefficients in

in such a way that at least one coefficient lies in

. As a corollary, if

, then all accumulation points of volumes are rational numbers. This proves a conjecture of Blache. For the set of standard coefficients

we prove that the minimal accumulation point is between

and

.
Multiview: a software package for multiview pattern recognition methods
Authors: Kanaan-Izquierdo Samir , Ziyatdinov Andrey , Burgueño Maria Araceli , Perera-Lluna Alexandre 
Published: December 2018

Abstract

Summary
Multiview datasets are the norm in bioinformatics, often under the label multi-omics. Multiview data are gathered from several experiments, measurements or feature sets available for the same subjects. Recent studies in pattern recognition have shown the advantage of using multiview methods of clustering and dimensionality reduction; however, none of these methods are readily available to the extent of our knowledge. Multiview extensions of four well-known pattern recognition methods are proposed here. Three multiview dimensionality reduction methods: multiview t-distributed stochastic neighbour embedding, multiview multidimensional scaling and multiview minimum curvilinearity embedding, as well as a multiview spectral clustering method. Often they produce better results than their single-view counterparts, tested here on four multiview datasets.

Availability and implementation
R package at the B2SLab site: http://b2slab.upc.edu/software-and-tutorials/ and Python package: https://pypi.python.org/pypi/multiview.

Supplementary information
Supplementary data are available at Bioinformatics online.