bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biochemical Diagnosis of Chromaffin Cell Tumors in Patients at High and Low Risk of Disease: Plasma versus Urinary Free or Deconjugated O-Methylated Catecholamine Metabolites
Authors: Eisenhofer Graeme , Prejbisz Aleksander , Peitzsch Mirko , Pamporaki Christina , Masjkur Jimmy , Rogowski-Lehmann Natalie , Langton Katharina , Tsourdi Elena , Pęczkowska Mariola , Fliedner Stephanie , Deutschbein Timo , Megerle Felix , Timmers Henri J L M , Sinnott Richard , Beuschlein Felix , Fassnacht Martin , Januszewicz Andrzej , Lenders Jacques W M 
Published: August 2018

AbstractBACKGROUNDMeasurements of plasma or urinary metanephrines are recommended for diagnosis of pheochromocytoma and paraganglioma (PPGL). What test offers optimal diagnostic accuracy for patients at high and low risk of disease, whether urinary free metanephrines offer advantages over deconjugated metanephrines, and what advantages are offered by including methoxytyramine in panels all remain unclear.METHODSA population of 2056 patients with suspected PPGLs underwent prospective screening for disease using mass spectrometric-based measurements of plasma free, urinary deconjugated, and urinary free metanephrines and methoxytyramine. PPGLs were confirmed in 236 patients and were excluded in others on follow-up evaluation.RESULTSMeasurements of plasma free metabolites offered higher (P &lt; 0.01) diagnostic sensitivity (97.9%) than urinary free (93.4%) and deconjugated (92.9%) metabolites at identical specificities for plasma and urinary free metabolites (94.2%) but at a lower (P &lt; 0.005) specificity for deconjugated metabolites (92.1%). The addition of methoxytyramine offered little value for urinary panels but provided higher (P &lt; 0.005) diagnostic performance for plasma measurements than either urinary panel according to areas under ROC curves (0.991 vs 0.972 and 0.964). Diagnostic performance of urinary and plasma tests was similar for patients at low risk of disease, whereas plasma measurements were superior to both urinary panels for high-risk patients.CONCLUSIONSDiagnosis of PPGLs using plasma or urinary free metabolites provides advantages of fewer false-positive results compared with commonly measured deconjugated metabolites. The plasma panel offers better diagnostic performance than either urinary panel for patients at high risk of disease and, with appropriate preanalytics, provides the test of choice. Measurements of methoxytyramine in urine show limited diagnostic utility compared with plasma.
Learning to weave for the luxury Indian and global fashion industries: The Handloom School, Maheshwar
Authors: Clifford Ruth 
Published: August 2018

Abstract
This article will draw upon ongoing research into design and business education for traditional artisans in India. It will focus specifically on the use of traditional crafts in the luxury Indian fashion industry, which has grown significantly in the last three decades, alongside one of the Ph.D. case studies – The Handloom School (THS) in Maheshwar, a small sari-weaving town in Madhya Pradesh state. The charitable organization WomenWeave was founded by Sally Holkar in 2003 to generate sustainable employment for women in Maheshwar and the surrounding region. While Maheshwar is known for its silk, cotton and zari (metallic yarn) fabrics and saris, WomenWeave started producing khadi (hand-spun, hand-woven yarn), which has been popular in high-end Indian and global fashion markets. THS is a recent initiative of WomenWeave, and teaches weavers from different parts of India business, design, IT and communication skills with a view to enabling them to start their own businesses and generate more sustainable livelihoods in their respective regions. Students also learn new weaving skills and multi-treddle techniques, and are encouraged to weave fabrics with more complex textures, patterns and colours than what they are used to, based on WomenWeave’s success with such fabrics. The school is in its early stages and the curriculum is continuously being revised and adapted. My recent ethnographic fieldwork in Maheshwar and other weaving regions in India has involved learning about the experiences of some of the students and graduates of THS, as well as the faculty, directors and administrative staff, over the past three years. This article will draw upon these experiences, while presenting some of the challenges the school is facing amidst a broad and lively debate on craft in India within the development, anthropological, design history and material culture discourses. I will address a number of questions such as: how can traditional craft meet the needs of the high-end fashion industry? How is education impacting ‘artisan’ and ‘designer’ collaborations and challenging the definition of these roles? Who owns traditional and other designs, and whose identity is expressed in the final product? It also explores how weavers are combining their traditional weaving skills gained in the home, along with institutionalized learning of business and design concepts; and to what extent education enables weavers to create products attuned to a contemporary market.
Communicating sustainability: Curating the ‘Making it Real’ installation, Trinity Leeds
Authors: McCreesh Natalie C. , Jones Christopher R. , McIntosh Alex , Storey Helen 
Published: August 2018

Abstract
With growing drives towards greater sustainability within the retail sector and growing requirement to conform to existing and emerging legislation, companies from ostensibly disparate sectors face the common challenge of encouraging the reduced consumption of saleable products, while simultaneously maintaining financial prosperity. Initially focused on knowledge exchange between the energy and water utilities and fashion retailers, TRANSFER (Trading Approaches to Nurturing Sustainable consumption in Fashion and Energy Retail) is now working together with a diverse group of large and SME (small- and medium-sized enterprises) retailers from a number of sectors, with the aim of successfully addressing this paradox. Combining the experiences of our commercial partners with academic expertise from a team of psychologists, fashion and management experts from the University of Sheffield and University of the Arts, London, TRANSFER is also investigating how efforts to promote sustainable consumption within retail are received and responded to by consumers. In fulfilling the project aims we hope to foster a more complete understanding of how retail sector initiatives can be successfully designed and implemented in order to have a positive impact on both retailers and their customers. This article provides a summary of the TRANSFER ‘Making it Real’ installation, held at Trinity Leeds shopping centre, (February 2015). This innovative, interactive exhibition was conceived of and developed upon the basis of discussions held with TRANSFER partners at a commercial partner workshop held in April 2014. TRANSFER is a knowledge exchange project funded by the Economic and Social Research Council (ESRC) Retail Sector Initiative 2013 (ES/L005204/1).
Mahatma Gandhi and the model of fashion education, activism and system(s) in India
Authors: Bhatt Asit 
Published: August 2018

Abstract
Prominent fashion educators, namely Lidewij Edelkoort and Jose Teunissen, have time and again pointed towards the crisis of a fast-fashion system marked by the rapid and excessive production–consumption patterns that manifest a throwaway society within the vast cultural wastelands. As Edelkoort has pointed out in her manifesto ‘Anti_Fashion’ (2015), it may sound quite ironic but we still educate our young people to become catwalk designers and unique individuals. However, our society demands exchange, new economy and working together in teams as well as groups. Pedagogy, in this precise sense apropos to the fast-fashion system, is indeed based upon a flat ontological ground or singular identity, which resembles a vast agricultural field protected by the scarecrow in order to harvest only a particular type of crop. What is required is a type of wilderness – an ecosystem; an interdependent as well as symbiotic relationship among the heterogeneous groups of individuals to realize life’s capacity to flourish and maximize its true potential. Here, the question is this: in what ways does fashion education play an active role in inculcating the values of cooperative, collaborative, correlative and collective modes of production–consumption within contemporary fashion system(s)? This article argues that the Gandhian model has great potential in articulating possibilities that are quite timely and crucial in relation to the present discourse on fashion system(s). The Gandhian model encompasses Mahatma Gandhi’s idea of ecology, work, crafts, education and fashion. The article suggests that the Gandhian model is subversive in nature and does inculcate the values of cooperative, collaborative, correlative and collective modes of production–consumption whilst facilitating a spirit of activism in order to imagine fashion outside the purview of industrial and post-industrial capitalism. Here, the dialectics of the life (praxis) versus mechanization (techne) appear to be an obvious trap, which the article avoids by developing a kind of dialogical framework – a relationship to the environment quite radically different than that of humanism and anthropocentrism.
Industry insight: Conscious consumption
Authors: Schultz-Clark Ophelia 
Published: August 2018

Abstract
These days, purchasing almost anything can be a veritable minefield: are these carrots organic? Is my eyeliner cruelty free? Can I afford to pay a little extra for a plant-based washing up liquid? The struggle is more than real – it is necessary. It shows that we are engaging with the all-too real problem of global warming, rather than burying our heads in the sand. For this reason, it is important we keep the environment in mind when we are making everyday choices, such as in our clothing. Whether you are a consumer, designer or manufacturer, it is important to include waste reduction in the goals of your efforts in the fashion industry. In this article, I will be sharing my views on why you should make the switch from mainstream to sustainable fashion and telling you a little bit about our brand, Madia & Matilda.
Can our clothes impact our well-being?
Authors: Olivia John Zoë 
Published: August 2018

Abstract
We have all been there: we put on an outfit, one we wore the previous week or previous day, and it just does not feel right. You look in the mirror and it does not work, the computer inside your head screams out: ‘YOUR IDENTITY HAS BEEN COMPROMISED’. As silly as this may seem, it is a familiar – and well-documented – story; we dress ourselves to reflect how we want to be perceived (Woodward 2007) and to reflect our identity. This might change on a daily basis: we might be cool and casual on a Monday and sharp as a point on Tuesday, but research shows wearing something that does not reflect how you feel can actually have a negative impact on your sense of well-being.
Multi-DOF compensation of piezoelectric actuators with recursive databases
Authors: Schindlbeck Christopher , Pape Christian , Reithmeier Eduard 
Published: August 2018

Abstract
Piezoelectric actuators are subject to nonlinear effects when voltage-driven in open-loop control. In particular, hysteresis and creep effects are dominating nonlinearities that significantly deteriorate performance in tracking control scenarios. In this paper, we present an online compensator suitable for piezoelectric actuators that is based on the modified Prandtl-Ishlinskii model and utilizes recursive databases for the compensation of nonlinearities. The compensator scheme is furthermore extended to systems with more than one degree of freedom (DOF) such as Cartesian manipulators by employing a decoupling control design to mitigate inherent cross-coupling disturbances. In order to validate our theoretical derivations, experiments are conducted with coupled trajectories on a commercial 3-DOF micro-positioning unit driven by piezoelectric actuators.
First report of Chlamydia psittaci seroprevalence in black-headed gulls (Larus ridibundus) at Dianchi Lake, China
Authors: Chang Hua , Han Jiangqiang , Yang Yan , Duan Gang , Zou Fengcai , Xiang Xun , Dai Feiyan 
Published: August 2018

AbstractChlamydiosis is an important zoonosis which can transmit from birds to humans, and investigation first reported the seroprevalence of Chlamydia psittaci in black-headed gulls (Larus ridibundus) at the Dianchi Lake, China. A total of 1029 serum samples collected from black-headed gulls between 2012-2015 were analyzed. The gulls were randomly caught and blood collected at Dianchi Lake, China. All the samples were analyzed for the presence of antibodies to C. psittaci by indirect hemagglutination assay (IHA). In this survey, the total infection rate was 11.86% (122/1029). The results of the present survey documented the existence of relatively high C. psittaci seroprevalence in black-headed gulls, which have a potential risk to the wild bird health and human health. Comprehensive practical control approaches and measures should be executed.
Managing inappropriate utilization of laboratory resources
Authors: Cadamuro Janne , Ibarz Mercedes , Cornes Michael , Nybo Mads , Haschke-Becher Elisabeth , von Meyer Alexander , Lippi Giuseppe , Simundic Ana-Maria 
Published: August 2018

Abstract

Background
The inappropriate use of laboratory resources, due to excessive number of tests not really necessary for patient care or by failure to order the appropriate diagnostic test, may lead to wrong, missed or delayed diagnosis, thus potentially jeopardizing patient safety. It is estimated that 5–95% of tests are currently used inappropriately, depending on the appropriateness criteria, thus significantly contributing to the potential of generating medical errors, the third leading cause of death in the US.

Content
In this review, we discuss the reasons as well as the medical and financial consequences of inappropriate utilization of laboratory tests. We then provide demand management (DM) tools as a means for overcoming this issue and also discuss their benefits, challenges, limitations and requirements for successful implementation.

Summary and outlook
When based on current evidence, adapted to local conditions and developed in close collaboration with clinicians, DM is a reasonable strategy for progressing toward better management of over- and underuse of laboratory resources.
Impacts of International Migration on Socio-Economic Development in Bangladesh
Authors: Sarker Masud , Islam Shahidul 
Published: August 2018

Abstract
International migration has positive impacts on socio-economic development in Bangladesh. Using secondary data, this paper explores the impacts of remittances on socio-economic development in Bangladesh. The article reveals that remittance has significant impacts on Bangladesh economy and socio-economic development, for example, reducing the poverty, increasing the household expenditure, saving, leading to maintain the quality of life as well as gender equality. Therefore, the government should take necessary steps to fostering international migration as a national strategy for economic development of Bangladesh.
Identification of Delamination in Composite Beams using the Fractal Dimension-Based Damage Identification Algorithm
Authors: Katunin Andrzej , Zuba Michał 
Published: August 2018

Abstract
Damage detection and identification is one of the most important tasks of proper operation of technical objects and structures. It is, therefore, essential to develop efficient and sensitive methods of early damage detection. Delamination is the type of damage occurring in laminated composites that is one of the most dangerous and most difficult to detect. In this paper, the computational study was performed on the numerical data of the modal shapes of laminated composite beams with simulated delaminations in order to detect them using a fractal dimension-based approach. The obtained results allowed for improvement of detection accuracy as compared to previously applied wavelet-based approach. An additional benefit was decreasing the computational time. Basing on the obtained results it is reasonable to consider the presented approach as a promising alternative to currently applied signal processing methods used for supporting non-destructive testing of structures.
Understanding the effect of weathering on adhesive bonds for wood composites using digital image correlation (DIC)
Authors: McKinley Paige , Sinha Arijit , Kamke Frederick A. 
Published: August 2018

Abstract
The quality of wood composites is dependent on the bondlines’ performance and their moisture resistance. The effect of moisture intrusion into bondlines is the focus of this study. The strain profile in the bondline during loading was investigated and the effects of weathering on the bondline were quantified by digital image correlation (DIC), while load deflection data were collected from lap-shear tests (LShTs). A total of 75 LShTs were evaluated including four different adhesive types with Douglas-fir wood, out of which 39 served as controls and 36 as substrates for weathering. The effect of weathering on failure load was not statistically significant. Only the bonded surface and adhesive type have significant effects on failure load, as well as the three-way interaction between the bonded surface, adhesive, and weathering, as revealed by three-way analysis of variance (ANOVA). The average effective shear moduli for the weathered samples were significantly lower than those for the control samples.
High Speed Radio over Fiber System for Wireless Local Area Networks by Incorporating Alternate Mark Inversion Scheme
Authors: Sharma Abhishek , Chauhan Priyanka 
Published: August 2018

Abstract
Radio over fiber (RoF) technique has revolutionized communication industry with its high data transmission rate and ability to carry the radio signal with speed of light. It finds its application in wireless local area networks (WLANs) due to easy of deployment and low cost. This paper utilizes alternate mark inversion (AMI) technique in wave length division multiplexing (WDM) scheme to further enhance data carrying capacity of the system. It is observed that proposed AMI-WDM scheme is better technique for providing high data rates and is confirmed via SNR, Q factor and eye diagrams.
Long-term thyroid disorders in pediatric survivors of hematopoietic stem cell transplantation after chemotherapy-only conditioning
Authors: Cima Luminita N. , Martin Sorina C. , Lambrescu Ioana M. , Stejereanu Lavinia , Zaharia Cristina , Colita Anca , Fica Simona 
Published: August 2018

Abstract

Background:
Thyroid dysfunction (TD) was usually described in hematopoietic stem cell transplantation (HSCT) recipients who were given total body irradiation (TBI) in the conditioning regimen. Because previous studies have reported discrepant results regarding the presence of long-term thyroid complications in HSCT survivors following chemotherapy-only conditioning, we investigated the frequency of thyroid abnormalities in a series of children treated with HSCT for different disorders without TBI as part of the conditioning protocol.

Methods:
We compared thyroid-stimulating hormone, free thyroxine, total triiodothyronine (TT3), anti-peroxidase (TPO Ab) and anti-thyroglobulin antibodies and thyroid volume z-score in 28 HSCT survivors and 16 healthy subjects matched for age and sex.

Results:
HSCT recipients had a higher frequency of TD and thyroid complications in total, including TD and euthyroid Hashimoto thyroiditis, compared to the control group. Patients transplanted for Hodgkin lymphoma (HL) were more likely to develop a thyroid complication compared to patients with non-malignant hematologic diseases and leukemia patients. BEAM (carmustine, etoposide, citarabin and melphalan) conditioning compared to busulfan (Bu) and fludarabine (Flu)-based regimens and autologous compared to allogenic grafting were associated with a higher prevalence of TD in our study. HSCT survivors had higher mean serum TT3 levels. A multivariate analysis revealed that autologous (auto)-HSCT recipients had higher mean serum titers of TPO Ab compared to allogenic (allo)-HSCT recipients and controls and the mean thyroid volume z-score was significantly higher in controls compared to auto-/allo-HSCT survivors.

Conclusions:
We identified a 35.7% prevalence of thyroid abnormalities, emphasizing the need for a long-term surveillance of thyroid function and morphology even in this group of patients who were not exposed to TBI.
Challenges in data storage and data management in a clinical diagnostic setting
Authors: Eck Sebastian H. 
Published: August 2018

Abstract
The implementation of next-generation sequencing (NGS) in a clinical diagnostic setting opens vast opportunities through the ability to sequence all genes contributing to a certain morbidity simultaneously at a cost and speed that is superior to traditional sequencing approaches. On the other hand, the practical implementation of NGS in a clinical diagnostic setting involves a variety of new challenges, which need to be overcome. Among these are the generation, analysis and storage of unprecedented amounts of data, strict control of sequencing performance, validation of results, interpretation of detected variants and reporting. In the following sections, key aspects of data management and integration will be discussed. In particular, issues of data storage, data analysis using in-house IT infrastructure vs. data analysis employing cloud computing and the need for data integration from different sources will be covered.
Catalytic properties of plate-like cadmium oxide nanoparticles in removal of sulfathiazole with anticancer activity
Authors: Hoseini Leila , Bagheri Azar 
Published: August 2018

Abstract
The study of the interaction of drugs with DNA is very exciting and significant not only for understanding the mechanism of the interaction but also for the design of new drugs. Here, we report the results of Fourier transform infrared (FT-IR) and ultraviolet (UV)-visible spectroscopy studies to determine the external binding modes of sulfathiazole (STZ), and the binding constant and stability of the STZ-DNA complex in aqueous solution. The results of absorption spectra showed that the interaction of STZ-DNA is weak because there is only a hyperchromic effect. A hyperchromic effect reflects the corresponding changes of DNA in its conformation and structure after the drug-DNA interaction has occurred. Spectroscopic evidence revealed that STZ binds DNA with an overall binding constant of K (STZ-DNA)=0.42×103
m
−1. FT-IR spectroscopy showed that the complexation of STZ with DNA occurred via A-T and PO2 groups. Nano cadmium hydroxide has been synthesized using hexamine as the template at room temperature. Then, this nano cadmium hydroxide recrystallizes into nano cadmium oxide (CdO) at 400°C for 2 h. The product was characterized by using X-ray diffraction and scanning electron microscopy. The presence of drugs in aquatic media has emerged in the last decade as a new environmental risk. The other aim of this study was to investigate the degradation of the STZ antibiotic by nanosized CdO under ultraviolet irradiation. Various experimental parameters, such as initial CdO concentration, initial pH, and reaction times, were investigated. According to the results, this method has a good performance in the removal of STZ.