bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serum level of nerve growth factor is a potential biomarker of conversion to bipolar disorder in women with major depressive disorder
Authors: Pedrotti Moreira Fernanda , Cardoso Taiane C. , Mondin Thaíse C. , Wiener Carolina D. , de Mattos Souza Luciano D. , Oses Jean P. , Jansen Karen , da Silva Ricardo A. 
Published: June 2019

AimThe aim of this study was to identify biomarkers associated with major depressive disorder (MDD) and conversion from MDD to bipolar disorder (BD) in an outpatient sample of women.MethodsThis was a longitudinal study including women diagnosed with MDD and aged 18 to 60 years. The follow‐up was 3 years. The diagnosis was performed using the Mini International Neuropsychiatric Interview Plus. Blood collection was just performed in the first phase. Serum interleukin‐6, tumor necrosis factor‐α, brain‐derived neurotrophic factor, glial cell‐derived neurotrophic factor, and nerve growth factor (NGF) levels were measured using a commercial immunoassay kit.ResultsWe included 156 women. The conversion rate from MDD to BD was 15.4% (n = 24). NGF serum levels were increased in patients who converted to BD compared to the remitted MDD group and current MDD group (P = 0.013). The Bonferroni post‐hoc test for multiple comparisons revealed significant differences for higher NGF levels in patients who converted to BD compared to patients with current MDD (P = 0.037). Interleukin‐6, tumor necrosis factor‐α, brain‐derived neurotrophic factor, and glial cell‐derived neurotrophic factor serum levels did not differ among the groups.ConclusionOur results suggest that NGF might be a useful biomarker associated with early detection of conversion to BD, helping clinicians in the clinical diagnosis.
Relationship context and personality shape people's preferences for network relationship partners
Authors: Porter Caitlin M. , Rigby James R. 
Published: June 2019

AbstractThis study investigates how people weight potential relationship partners' personal characteristics (i.e., warmth and competence) when deciding to initiate professional versus personal network relationships, and it also examines how certain personality traits (extraversion and conscientiousness) shape this process. Results from two samples indicate that people tend to value competence more highly when initiating professional relationships, whereas they tend to value warmth more highly when initiating personal relationships. Furthermore, neither extraversion nor conscientiousness was related to how people weighted competence when initiating professional relationships. However, supplementary analyses demonstrated that people high in conscientiousness tend to value competence and people high in agreeableness tend to value warmth in their network relationship partners, regardless of whether they are initiating a professional or personal relationship.
Physical activity and aerobic fitness in children after liver transplantation
Authors: Bos G. J. F. Joyce , Lelieveld Otto T.H.M. , Scheenstra Rene , Sauer Pieter J. J. , Geertzen Jan H. B. , Dijkstra Pieter U. 
Published: June 2019

AbstractTo determine physical activity (PA), aerobic fitness, muscle strength, health‐related quality of life (HRQOL), fatigue, and participation in children after liver transplantation. Children, 6‐12 years, at least one year after liver transplantation, participated in this cross‐sectional study. Measurements: Time spent in moderate to vigorous PA (MVPA) was measured using an accelerometer, and aerobic fitness (VO2 peak) was measured by cardiopulmonary exercise testing. Muscle strength was measured by hand‐held dynamometry. Fatigue was measured using the multidimensional fatigue scale, and HRQOL with the Pediatric Quality of life Core scales and leisure activities was measured using the Children's Assessment of Participation and Enjoyment. Outcomes (medians and interquartile range (IQR)) were compared to norm values. Twenty‐six children participated in this study (14 boys, age 9.7 years, IQR 7.7;11.4). Children spent 0.8 hours/d (IQR 0.6;1.1) on MVPA. One child met the recommendation of at least 1 hour of MVPA every day of the week. Aerobic fitness was similar to norms (VO2 peak 1.4 L/min, IQR 1.1;1.7, Z‐score −0.3). Z‐scores of muscle strength ranged between −1.4 and −0.4 and HRQOL and fatigue between −2.3 and −0.4. Participation was similar to published norms (Z‐scores between −0.6 and 0.6). Young children after liver transplantation have similar MVPA patterns and aerobic fitness compared to published norms. Despite lower HRQOL, more fatigue, and less muscle strength, these children have similar participation in daily activities. Although children do well, it remains important to stimulate PA in children after liver transplantation in the context of long‐term management.
A survey of the anesthetic management of pediatric kidney transplantation in France
Authors: Marsac Lucile , Michelet Daphné , Sola Chrystelle , Didier‐Vidal Anne , Combet Sylvie , Blanc Frederic , Orliaguet Gilles , Aubineau Jean‐Vincent , Julien‐Marsollier Florence , Brasher Christopher , Dahmani Souhayl 
Published: June 2019

AbstractBackgroundRenal transplantation is the best available therapeutic option for end‐stage renal failure in both children and adults. However, little is known about anesthetic practice during pediatric renal transplantation.Material and MethodsThe study consisted of a national survey about anesthetic practice during pediatric renal transplantation in France. French tertiary pediatric centers performing renal transplants were targeted, and one physician from each team was asked to complete the survey. The survey included patient data, preoperative assessment and optimization data, and intraoperative anesthesia data (drugs, ventilation, and hemodynamic interventions).ResultsTwenty centers performing kidney transplantation were identified and contacted to complete the survey, and eight responded. Surveyed centers performed 96 of the 122 pediatric kidney transplantations performed in France in 2017 (79%). Centers consistently performed echocardiography and ultrasound examinations of the great veins preoperatively and consistently employed esophageal Doppler cardiac output estimation and vasopressors intraoperatively. All other practices were found to be heterogeneous. Central venous pressure was monitored in six centers, and dopamine was administered perioperatively in two centers.ConclusionsThe current study provides a snapshot of the perioperative management of pediatric kidney transplantation in France. Results emphasize the need for both standardization of practice and awareness of recent evidence against the use of CVP monitoring and dopamine infusions.
Donor‐specific antibodies in a pediatric kidney transplant population—Prevalence and association with antiproliferative drug dosing
Authors: Strommen Amanda M. , Moss Mary C. , Goebel Jens , Bock Margret 
Published: June 2019

AbstractPrevalence and implications of anti‐HLA class I and class II antibodies are beginning to be better characterized in pediatric kidney transplant recipients. dnDSA formation is predictive of AMR and downstream diminished graft function and survival. However, risk factors for the development of dnDSA are not well defined in this patient population. After introducing DSA surveillance into our pediatric kidney transplant program, we are reporting the prevalence of class I and class II DSA in 67 otherwise stable recipients. Secondary end‐points included risk factors for DSA development and assessment of graft function. Significantly, lower median daily MMF doses were observed in patients with DSAs compared to patients without DSAs (371 vs 617 mg/m2/d, respectively; P = 0.035). Class II DSA formation was more common, with a prevalence of 17.9%, as compared to 10.4% for class I DSA. Estimated glomerular filtration rate was also decreased in patients with positive DSA vs those with negative titers (71, SD 25 vs 78, SD 29 mL/min/1.73 m2, respectively; P = 0.034). We conclude that reduced‐dose MMF is associated with dnDSA and DSA is associated with diminished graft function in stable pediatric kidney transplant recipients.
Geometry Effects on Light‐Harvesting Complex's Light Absorption and Energy Transfer in Purple Bacteria
Authors: Zeng Lingyu , Liao Zeyang , Wang Xue‐hua 
Published: June 2019

AbstractLight‐harvesting complexes (LHC) in photosynthetic organisms perform the major function of light absorption and energy transportation. Optical spectrum of LHC provides a detailed understanding of the molecular mechanisms involved in the excitation energy transfer (EET) processes, which has been widely studied. Here, we study how the geometric property of LHC in Rhodospirillum (Rs.) molischianum would affect its spectral characteristics and energy transfer process. By adopting the effective Hamiltonian and the dipole–dipole approximation, we calculate the exciton level structures for the LH2 ring and LH1 ring and the energy transfer time between different LHCs under various structural parameters and different rotational symmetries. Our numerical results show that the LHC's absorption peaks and the energy transfer time between different LHCs can be modified by changing the geometric configurations. Our study may be beneficial to the applications in designing highly efficient photovoltaic cell and other artificial photosynthetic systems.
Beyond client criminalization: Analyzing collaborative governance arrangements for combatting prostitution and trafficking in Sweden
Authors: Erikson Josefina , Larsson Oscar L. 
Published: June 2019

AbstractSweden is well known as the first country in the world to adopt client criminalization in an effort to control and eventually eliminate prostitution. Less attention has been paid to the emergence of extensive collaborative governance arrangements that serve as complements to the legal framework. The aim of this article is to provide new knowledge as it investigates the multifaceted ways in which governance arrangements have developed in Sweden, employing collaborative governance theories and the Regulatory–Intermediaries–Target model for this purpose. The strategies of responsibilization directed toward target groups that have been utilized to implement policies to control prostitution and trafficking are also explored. The article analyzes not only the rationale behind the adoption of collaborative governance in Sweden, but also the complex governance practices that have emerged in this regard, in which a range of actors are involved in policymaking and application as well as regulation. We conclude that the previous understanding of the Swedish model needs to be revised, and that although collaborative governance has made a fruitful contribution to the field in question, it also introduces new types of problems, particularly a significant increase in informality and decisionmaking outside the legal framework, primarily by civil society actors.
Sensitivity Analysis for Inverse Probability Weighting Estimators via the Percentile Bootstrap
Authors: Zhao Qingyuan , Small Dylan S. , Bhattacharya Bhaswar B. 
Published: June 2019

SummaryTo identify the estimand in missing data problems and observational studies, it is common to base the statistical estimation on the ‘missingness at random’ and ‘no unmeasured confounder’ assumptions. However, these assumptions are unverifiable by using empirical data and pose serious threats to the validity of the qualitative conclusions of statistical inference. A sensitivity analysis asks how the conclusions may change if the unverifiable assumptions are violated to a certain degree. We consider a marginal sensitivity model which is a natural extension of Rosenbaum’s sensitivity model that is widely used for matched observational studies. We aim to construct confidence intervals based on inverse probability weighting estimators, such that asymptotically the intervals have at least nominal coverage of the estimand whenever the data-generating distribution is in the collection of marginal sensitivity models. We use a percentile bootstrap and a generalized minimax–maximin inequality to transform this intractable problem into a linear fractional programming problem, which can be solved very efficiently. We illustrate our method by using a real data set to estimate the causal effect of fish consumption on blood mercury level.
Genetic structure, species limits and evolution of the parasitoid wasp genus Stenocorse (Braconidae: Doryctinae) based on nuclear 3RAD and mitochondrial data
Authors: Delgado‐Machuca Natalia , Meza‐Lázaro Rubi N. , Romero‐Nápoles Jesús , Sarmiento‐Monroy Carlos E. , Amarillo‐Suárez Ángela R. , Bayona‐Vásquez Natalia J. , Alejandro Zaldívar‐Riverón 
Published: June 2019

AbstractStenocorse (Braconidae: Doryctinae) is an ectoparasitoid wasp genus widely distributed from southern U.S.A. to central Argentina, which is known to attack over 60 bruchine beetle species that feed on a variety of legumes. This genus currently comprises a single described species, S. bruchivora (Crawford, 1910), though it is probably composed of additional, morphologically similar species. In this study we investigated genetic structure, species limits and evolutionary relationships of sampled populations of Stenocorse obtained along its known geographic distribution, with an emphasis on the Mexican territory. For this, we generated DNA sequences from both the mitochondrial (mt) barcoding locus and nuclear genome data obtained with the 3RAD technique. The Bayesian phylogenetic reconstructions based on the two datasets were mostly congruent, both showing clear geographic structure. Four clusters were recovered with nuclear data, which were also congruent with the geographic distribution of the samples and the species delimitation analyses. We delimited six evolutionary lineages with the two data sources, and three additional species were also delimited with the COI locus alone. Stenocorse probably originated during the mid‐ to early Miocene, and the diversification events that led to its current species distribution probably occurred between the early Pliocene and late Pleistocene. Our species delineation analyses, phylogenetic reconstructions and rearing records suggest that the species of Stenocorse have generalist feeding habits, contrary to what was expected due to host plant specialization of the bruchine species and the cascading effect that this could have in the species diversification of their parasitoids.
Peripheral blood smear findings in a kidney transplant recipient with disseminated histoplasmosis and elevated Aspergillus galactomannan
Authors: McCurdy Lewis , Wheat Lawrence Joseph , Block Jared , Gajurel Kiran 
Published: June 2019

AbstractWe report a case of disseminated histoplasmosis in a renal transplant recipient who presented with a nodular pulmonary lesion and elevated serum and bronchoalveolar lavage (BAL) Aspergillus galatomannan. This almost led to an erroneous diagnosis of invasive aspergillosis since the donor respiratory tract was known to be colonized with Aspergillus terreus. However, distinctive intracelluar Histoplasma yeasts on peripheral blood smear led to early diagnosis and appropriate treatment. The cross‐reactivity between Aspergillus galactomannan and Histoplasma antigen is discussed further.
School-based obesity prevention programs in rural communities: a scoping review protocol
Authors: Robinson Jennifer C. , Lim Crystal S. , Hinton Elizabeth , Pintado Irene , Gamble Abigail , Compretta Caroline , Ravola Martha 
Published: June 2019

ABSTRACT

Objective:
The objective of this scoping review is to map the available literature on school-based obesity prevention programs in rural communities.

Introduction:
Significant health disparities are associated with childhood obesity, and these disparities disproportionately affect children in disadvantaged communities, such as rural areas. Youth in rural areas are 26% more likely to be obese than youth in urban communities. To combat obesity in children, schools have become an avenue for educating children about the importance of healthy diet and physical activity. Although many school-based obesity prevention programs have been implemented in recent years, more information is needed on programs in rural communities.

Inclusion criteria:
This scoping review will consider studies that include children 5 to 18 years of age who are enrolled in elementary, middle or high school in a rural setting and that investigate school-based obesity prevention programs. Studies that include children who are in non-rural areas, who are home-schooled, who are in an alternative setting (e.g. juvenile detention) or who are hospitalized will be excluded. Studies published in English since 1990 will be included.

Methods:
Multiple databases will be searched, including PubMed, CINAHL, ERIC, Embase, Scopus and Academic Search Premier. Trials registers and gray literature will also be searched. After screening the titles and abstracts of identified citations, potentially relevant studies will be retrieved in full. Data will be extracted by independent reviewers and presented in a diagrammatic or tabular form, accompanied by a narrative summary.
Sulfide oxidation affects the preservation of sulfur isotope signals
Authors: Findlay Alyssa J. , Boyko Valeria , Pellerin André , Avetisyan Khoren , Guo Qingjun , Yang Xi , Kamyshny Alexey 
Published: June 2019

Abstract
The accumulation of oxygen in Earth’s atmosphere and oceans in the late Archean had profound implications for the planet’s biogeochemical evolution. Oxygen impacts sulfur cycling through the oxidation of sulfide minerals and the production of sulfate for microbial sulfate reduction (MSR). The isotopic signature of sulfur species preserved in the geologic record is affected by the prevailing biological and chemical processes and can therefore be used to constrain past oxygen and sulfate concentrations. Here, in a study of a late Archean analogue, we find that the sulfur isotopic signature in the water column of a seasonally stratified lake in southern China is influenced by MSR, whereas model results indicate that the isotopic signature of the underlying sediments can be best explained by concurrent sulfate reduction and sulfide oxidation. These data demonstrate that small apparent sulfur isotope fractionations (δ34Ssulfate-AVS = 4.2‰–1.5‰; AVS—acid volatile sulfides) can be caused by dynamic sulfur cycling at millimolar sulfate concentrations. This is in contrast to current interpretations of the isotopic record and indicates that small fractionations do not necessarily indicate very low sulfate or oxygen.
Epidemiology of injuries in professional football: a systematic review and meta-analysis
Authors: López-Valenciano Alejandro , Ruiz-Pérez Iñaki , Garcia-Gómez Alberto , Vera-Garcia Francisco J , De Ste Croix Mark , Myer Gregory D , Ayala Francisco 
Published: June 2019

ObjectiveWe performed a systematic review and meta-analysis of epidemiological data of injuries in professional male football.MethodForty-four studies have reported the incidence of injuries in football. Two reviewers independently extracted data and assessed trial quality using the Strengthening the Reporting of Observational Studies in Epidemiology statement and Newcastle Ottawa Scale. Studies were combined in a pooled analysis using a Poisson random effects regression model.ResultsThe overall incidence of injuries in professional male football players was 8.1 injuries/1000 hours of exposure. Match injury incidence (36 injuries/1000 hours of exposure) was almost 10 times higher than training injury incidence rate (3.7 injuries/1000 hours of exposure). Lower extremity injuries had the highest incidence rates (6.8 injuries/1000 hours of exposure). The most common types of injuries were muscle/tendon (4.6 injuries/1000 hours of exposure), which were frequently associated with traumatic incidents. Minor injuries (1–3 days of time loss) were the most common. The incidence rate of injuries in the top 5 European professional leagues was not different to that of the professional leagues in other countries (6.8 vs 7.6 injuries/1000 hours of exposure, respectively).ConclusionsProfessional male football players have a substantial risk of sustaining injuries, especially during matches.
Confirmed cardiac output on emergency medical services arrival as confounding by indication: an observational study of prehospital airway management in patients with out-of-hospital cardiac arrest
Authors: Sakurai Atsushi , Kinoshita Kosaku , Maeda Yukihiro , Homma Yosuke , Tahara Yoshio , Yonemoto Naohiro , Nagao Ken , Yaguchi Arino , Morimura Naoto 
Published: June 2019

ObjectivesMany registry studies on patients with out-of-hospital cardiac arrest (OHCA) have reported that conventional bag-valve-mask (BVM) ventilation is independently associated with favourable outcomes. This study aimed to compare the data of patients with OCHA with confirmed cardiac output on emergency medical services (EMS) arrival and consider the confounding factors in prehospital airway management studies.MethodsThis was a cohort study using the registry data for survivors after out-of hospital cardiac arrest in the Kanto region at 2012 in Japan (SOS-KANTO 2012). Survivors who received advanced airway management (AAM) group and a BVM group were compared for confirmed cardiac output on EMS arrival and neurolgical outcome at 1 month. Favourable neurological outcome was defined as a score of one or two on the Cerebral Performance Categories Scale. Multivariable logistic regression was used to adjust the neurological outcome by age, gender, cardiac aetiology, witnessed arrest, shockable rhythm, cardiopulmonary resuscitation performed by a bystander, BVM at prehospital ventilation and presence of confirmed cardiac output on EMS arrival.ResultsA total of 16 452 patients were enrolled in the SOS-KANTO 2012 study, and of those data 12 867 were analysed; 5893 patients comprised the AAM group and 6974 comprised the BVM group. Of the study participants, 386 (2.9%) had confirmed cardiac output on EMS arrival; 340 (2.6%) of the entire study group had a favourable neurological outcome. The proportion of patients with confirmed cardiac output on EMS arrival was significantly higher in the BVM group (272: 3.9%) than in the AAM group (114: 1.9%) (95% CI: 1.65 to 2.25). The proportion of patients with favourable neurological outcomes was 30% (117/386) in those with cardiac output on EMS arrival compared with 1.8% (223/12481) in those without. The OR for a good neurological outcome with BVM decreased from 3.24 (2.49 to 4.20) to 2.60 (1.97 to 3.44) when confirmed cardiac output on EMS arrival was added to the multivariable model analysis.ConclusionConfirmed cardiac output on EMS arrival should be considered as confounding by indication in observational studies of prehospital airway management.