bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemanfaatan Limbah Pecahan Beton Sebagai Pengganti Sebagian Agregat Kasar Terhadap Kuat Tekan Beton Dengan Mutu F’C 18,68 MPa
Authors: Dwi Prastiyo Firmandika , Cahyono Iwan , Hidayat Ruslan 
Published: November 2024

Beton merupakan faktor utamadalam bidang kontruksi pada saat ini. Sering kita jumpai material utama dalam pembuatan suatu kontruksi bangunan adalah beton. Jalan, jembatan, gedung bahkan dinding penahan pada bendungan pun juga dari beton.Beton dipilih sebagai bahan bangunan karena mempunyai kekuatan tekan yang tinggi. Secara struktural beton mempunyai tegangan tekan cukup besar, sehingga bermanfaat untuk struktur yang menahan gaya-gaya tekan. Akan tetapi, beton juga memiliki kelemahan yaitu kuat tariknya sangat rendah dan bersifat getas (britle), sehingga untuk menahan gaya tarik tersebut ditambahkan baja tulangan. Penambahan baja tulangan pun belum memberikan hasil yang optimal. Sering kita jumpai pada suatu balok terdapat retak halus yang disebabkan oleh gaya tarik yang bekerja pada balok tersebut.Metode penelitian yang digunakan adalah kajian eksperimental di laboratorium. Pada penelitian ini dilakukan 5 (lima) variasi persentase penambahan limbah pecahan beton, yaitu 0% (kontrol); 10%; 20%; 30%; 40% dan 50% dari berat semen awal dengan jumlah benda uji setiap variasi persentase berjumlah 5. Pengujian kuat tekan beton dilakukan ketika beton mencapai umur 28 hari.
The Uneven Geography of Access to Live Performances of Western Classical Music in the United States
Authors: Jones Will , Kim Junghwan 
Published: November 2024

This study evaluates accessibility to live performances of Western classical music across 3,109 U.S. counties. It analyzes 100 popular concertos and symphonies from this genre (e.g., Beethoven’s Symphony No. 9, Ode to Joy) to reveal socio-spatial disparities. Midwestern counties show poorer accessibility than West and East Coasts, with the highest mean accessibility scores in the fall and the lowest in summer. A hurdle model indicates that counties with higher population density are significantly associated with greater accessibility. An interactive online StoryMap embedded with recorded performances offers a synesthetic experience for exploring accessibility to live Western classical music performances.
Impacto de la Industria 4.0 en los sistemas mecatrónicos: una revisión de normativas internacionales
Authors: Carrera Agama Daniel Ernesto , Tibanquiza Chuncho Santiago Efraín , Taboada Flores Pablo Hernán , Ocaña Pañora Lando Stephen 
Published: November 2024

Introducción: La industria 4.0 ha revolucionado los sistemas industriales con tecnologías como IoT, IA y CPS, lo que ha impulsado el rediseño de los sistemas mecatrónicos. Sin embargo, la implementación de estas tecnologías requiere la aplicación adecuada de normativas internacionales para garantizar su seguridad y eficiencia. Objetivos: Este artículo revisa las normativas internacionales que guían la implementación de las tecnologías de la Industria 4.0 en los sistemas mecatrónicos, evaluando su impacto y detectando vacíos normativos que necesitan ser abordados. Metodología: Se realizó una revisión documental de normativas y publicaciones entre 2015 y 2024, enfocada en los estándares más relevantes para IoT, IA y CPS, analizando su aplicabilidad mediante un análisis comparativo. Desarrollo: Se revisaron normativas clave como ISO/IEC 30141 (IoT), ISO/IEC JTC 1/SC 42 (IA), e IEC 61508 (CPS), que proporcionan marcos para la interoperabilidad, seguridad y eficiencia en los sistemas mecatrónicos. Discusión: Se identificaron vacíos normativos, especialmente en ciberseguridad para IoT y CPS, y se subrayó la necesidad de mayor claridad en las normativas emergentes sobre IA. Resultados: Las normativas actuales son sólidas, pero necesitan mejoras en ciberseguridad e interoperabilidad para optimizar la implementación de tecnologías de la Industria 4.0 en la mecatrónica. Conclusiones: Las normativas internacionales son clave para la adopción de la Industria 4.0 en la mecatrónica, aunque se deben abordar áreas de mejora para una integración completa de estas tecnologías. Este análisis permite identificar áreas de mejora crítica en las normativas actuales, aportando recomendaciones para la implementación segura y eficiente de tecnologías de la Industria 4.0 en la ingeniería mecatrónica. Área general: Tecnologías emergentes aplicadas a la Industria 4.0. Área específica: Normativas internacionales para IoT, IA y CPS en sistemas mecatrónicos. Tipo de estudio: Investigación documental y bibliográfica.
Pembinaan Etika Komunikasi, Ketahanan dan Kesehatan Keluarga, serta Manajemen Keuangan: Pembinaan Majelis dan Jemaat di Gereja Toraja Kuala Lumpur Malaysia
Authors: Mangani Ktut Silvanita , Rantung Djoys A. , Nadeak Bernadetha , Limbong Mesta 
Published: November 2024

Abstrak Dalam menjalankan tugas pelayanannya, gereja perlu memahami etika berkomunikasi supaya terjadi komunikasi yang baik, dapat dimengerti dan diterima sehingga pelayanan gereja tertata dengan baik. Sebagai lembaga, gereja perlu untuk menata diri dengan segala risiko yang harus dihadapi. Hal itu menunjukkan perlunya manajemen pendidikan dan pengelolaan keuangan yang baik dalam gereja. Disamping itu, diperlukan ketahanan keluarga dan kesehatan dalam membangun hubungan antar anggota keluarga, sehingga tercipta hubungan yang harmonis dalam membangun jemaat yang kristiani. Pembinaan ini bertujuan memberi pemahaman dalam etika komunikasi, ketahanan dan kesehatan keluarga, serta manajemen keuangan dalam gereja. Menggunakan metode ceramah dan diskusi. Kegiatan ini mendapat sambutan yang sangat baik dari seluruh peserta yang terlihat dari antusiasme mereka dalam mengikuti pembinaan ini. Mereka juga berharap UKI dapat memberikan pelatihan lanjutan dan kegiatan-kegiatan yang lain.
Peningkatan Produktivitas Tanaman Hortikultura Melalui Smart Watering System di Kelurahan Klasuluk Provinsi Papua Barat Daya
Authors: Sahiruddin  , Prabawati Ratna , Aprianto Aci , Jare Petronela , Karay Kundrat agustinus 
Published: November 2024

Kelurahan Klasuluk merupakan salah satu kelurahan yang berada di Distrik Mariat Kabupaten Sorong, Papua Barat Daya. Secara garis besar, masyarakat Kelurahan Klasuluk bermata pencaharian sebagai petani. Komoditi yang paling banyak ditanam oleh masyarakat Kelurahan Klasuluk adalah tanaman Hortikultura. Kondisi tanah yang kering dan sistem penyiraman yang masih menggunakan peralatan manual menjadi penyebab rendahnya produktivitas tanaman hortikultura di kelurahan Klasuluk khususnya kelompok tani Tunas Siaga. Metode pelaksanaan pengabdian ini yaitu (1) Sosialisasi,(2) pelatihan, (3) penerapan teknologi,(4) pendampingan dan evaluasi Program. Hasil dari program pengabdian ini yaitu penerapan teknologi smart watering system dan pelatihan penggunaan teknologi tersebut dapat meningkatkan produktivitas tanaman Hortikultura dan meningkatkan nilai ekonomi masyaraka di kelurahan Klasuluk pada kelompok tani Tunas Siaga. Dari hasil program pengabdian ini dapat disimpukan bahwa teknologi smart watering system dapat meningkatkan produktivitas tanaman Hortikultura dan sangat dibutuhkan oleh kelompok tani Tunas Siaga.
THE EFFECT OF ADDING DRIED MORINGA OLEIFERA L. ON PHYSICOCHEMICAL CHARACTERISTICS AND ORGANOLEPTICS PROPERTY CRACKERS
Authors: Nisfi Lailatun , Maghfiroh Khoirin 
Published: November 2024

Moringa oleifera L. leaf contain energy, fat, protein, carbohydrates, fiber, vitamin A, and vitamin C. Crackers are a processed food made from a hard dough. The addition of dried Moringa oleifera L. leaf is expected to enhance the nutritional value and turn crackers into a functional food with benefits. This study aims to determine the influence of adding dried Moringa oleifera L. leaf on the antioxidant content and organoleptic properties, including taste, color, aroma, and texture of the crackers. The research was conducted at the Food Processing and Biochemistry Laboratory of Yudharta University, Pasuruan, and then Nutrition Laboratory of Airlangga University Surabaya and then Basic Laboratory of chemistry and biology of Hang tuah University Surabaya. from April to June 2023. The research method employed a Completely Randomized Design with six treatments (0%, 5%, 10%, 15%, 20%, and 30%) repeated three times, resulting in 18 experiments. Physicochemicals data analysis used Minitab software to conduct Analysis of Variance, and Tukey Method was applied for notation determination. Organoleptic testing employed the Friedman test, while the best treatment was determined using the modified De Garmo Effective Index test by Susrini (2003). The results indicate that the addition of dried Moringa oleifera L. leaf significantly affected (p<0.05) the antioxidant activity, taste, color, aroma, and texture of the crackers. The best treatment was P1 (195 grams of dried moringa oleifera: 5 grams of dried Moringa oleifera L. leaf ) with an antioxidant activity of 91.1% Breaking power of 3.67%, moisture content of 5.98%, ash content of 3.3%,and high organoleptic values for taste 3,64%, aroma 4,32%, color 4,32%, and texture 4,08%. The addition of moringa oleifera L. leaf to crackers can enhance the nutritional value of the crackers.
Correlation Between Mother’s Nutritional Expertise and Toddler’s Stunting Incidence in Wainyapu Village
Authors: Pandi Mariana , Sari Ni Luh Putu Dian Yunita , Prihandhani IGAA Sherlyna , Triana Komang Yogi 
Published: November 2024

Stunting is one of the world's nutritional challenges, particularly in impoverished and emerging countries. Stunting is an issue since it is connected with a higher risk of morbidity and mortality, as well as inadequate brain development, which leads to delayed motor development and stunted cerebral growth. The mother's health and nutritional status before and throughout pregnancy, the mother's body posture, the close spacing of pregnancies, the mother's adolescence, and poor dietary intake during pregnancy all have an impact on fetal growth and stunting risk. Stunting is influenced by the mother's nutritional expertise. This study aimed to evaluate the correlation between mothers’ nutritional expertise and the toddlers’ stunting incident in Wainyapu Village. This quantitative study employed an analytical survey design and a cross-sectional approach method. The population in this study were mothers who had toddlers 12-59 months and lived in Wainyapu Village. This study employed total sampling technique, with a questionnaire on mothers’ nutritional expertise as the research instrument. The Spearman correlation test was employed during data analysis. The findings yielded that the level of mothers’ nutritional expertise was mostly in the poor category (76.9%), with the incidence of stunting in toddlers as high as (75%), and there was a significant correlation between mothers’ nutritional expertise and the toddlers’ stunting incident as shown by Spearman correlation results were 0.945 with Sig p-value <0.01. It is expected that this study can provide mothers some information to better understand the importance of toddlers’ nutritional expertise in order to avoid stunting
Impact of physical indicators on ocular development in preschool children
Authors: Liu Xiangxiang , Fu Jing , Li Lei , Liu Peipei , Sun Yunyun , Li Huijian , Li Yuanbin , Zhu Bidan , Wang Shana , Qin Xi 
Published: November 2024

ObjectiveUnderstanding the impact of early childhood physical growth on visual development is crucial, as this period marks a critical phase for foundational physical and ocular maturation. The aim of the current study was to investigate the associations between the anthropometric indicators of height, weight, and body mass index (BMI), as well as visual acuity, refraction, and ocular biometrics, in Chinese preschool children.MethodsThis cross-sectional study consisted of 1,477 Chinese 3- to 6-year-old preschool children from nine kindergartens in Tongzhou District, Beijing. Demographic data, height and weight were measured according to a standard protocol, and BMI was calculated. Refractive error was measured via autorefraction in eyes under cycloplegia. Axial length (AL), anterior chamber depth (ACD), lens thickness, and corneal curvature were measured via an IOL Master. The axial length–corneal radius (AL–CR ratio) was defined as the AL divided by the mean corneal radius of curvature. Multivariate linear regression models were used to explore the cross-sectional associations between physical indicators (height, weight and BMI) and visual acuity and ocular developmental parameters in boys and girls.ResultsCompared with the children in the fourth quartile for height for a given age and sex, the visual acuity in the fourth quartile was 0.08 less, the refraction was 0.11 D more negative (1.22 D versus 1.33 D), the axial length was 0.62 mm longer, the anterior chamber depth was 0.18 mm deeper, the lens thickness was 0.13 mm thinner, the corneal radius of curvature was 0.1 mm less, and the AL-CR ratio was higher after adjustments were made for age and weight. The association between BMI and visual acuity was statistically significant in girls but not in boys. Older and more obese children had better visual acuity (p &lt; 0.001) after adjustments were made for age.ConclusionHeight and higher BMI remained independently related to VA condition, AL and ACD elongation, and corneal flattening in preschool children after controlling for various covariates. These results provide critical insights into pediatric ocular health and emphasize the importance of early detection and intervention in both physical and ocular health in early childhood development.
Analysis of translatomic changes in the Ubqln2P497S model of ALS reveals that motor neurons express muscle-associated genes in non-disease states
Authors: Stansberry Wesley M. , Fiur Natalie C. , Robins Melissa M. , Pierchala Brian A. 
Published: November 2024

IntroductionAmyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by progressively worsening motor symptoms that lead to eventual fatal paralysis. The number of gene mutations associated with ALS have increased dramatically in recent years, suggesting heterogeneity in the etiology of ALS and the need to develop new models of the disease that encompass these pathologies. In 2011, mutations in the UBQLN2 gene were identified in families with both ALS and frontotemporal dementia (FTD) and have since been linked to ubiquitinated TDP43 inclusion pathology. The involvement of UBQLN2 in ubiquitination and proteasome function suggests an important role in proteostasis, which is reported to be impaired in ALS.MethodsA UBQLN2 mouse model was generated for the P497S mutation and recapitulates some of the motor symptoms of ALS. We utilized ribosomal profiling followed by mRNA sequencing of associated transcripts to characterize gene expression changes of motor neurons in the Ubqln2P497S model and evaluated ALS phenotypes in these animals.ResultsAt 12 months of age, we observed reduced motor neuron survival and neuromuscular junction denervation in these mice that translated into motor deficits observed in locomotor behavioral trials. The sequencing of motor neuron transcripts revealed that Wnt pathways and muscle-related transcripts were downregulated in Ubqln2P497S mice, while metabolic pathways were upregulated.DiscussionSurprisingly, genes often reported to be muscle-specific, such as Desmin and Acta1, were expressed in motor neurons and were dramatically downregulated in symptomatic Ubqln2P497S mice. The expression of muscle transcripts by motor neurons suggests their potentially supportive role in skeletal muscle maintenance.
Exploring the molecular profile of localized colon cancer: insights from the AIO Colopredict Plus registry
Authors: Ekmekciu Ira , Zucha Doreen Maria , Christmann Jens , Wisser Sarah , Heuer Vera , Sargin Buelent , Hollerbach Stephan , Lamberti Christof , Müller Lothar , Lugnier Celine , Verdoodt Berlinda , Denz Robin , Terzer Tobias , Feder Inke , Reinacher-Schick Anke , Tannapfel Andrea , Tischoff Iris 
Published: November 2024

IntroductionUnderstanding the mutational landscape of colon cancer (CC) is crucial for targeted therapy development. Microsatellite instability (MSI-H), rat sarcoma (RAS), and B-Raf proto-oncogene, serine/threonine kinase (BRAF) mutations (MT) are pivotal markers. Further investigation into clinicopathological features of RAS and BRAF MT in microsatellite stable (MSS) and MSI-H tumors is warranted.MethodsA retrospective analysis of 4883 localized CC patients (pts.) was conducted. Molecular profiling assessed MSI, KRAS, NRAS, and BRAF MT. Correlation with clinicopathological data employed ANOVA and Chi-square tests. Disease-free survival (DFS) and overall survival (OS) were analyzed adjusting for age, gender, sidedness, UICC stage, Charlson Comorbidity Index (CCI). A Cox model incorporated all variables as covariates.ResultsThis analysis included 4883 pts. (2302 female/2572 male, 3865 (79.2%) MSS, 1018 (20.8%) MSI-H). MSS pts. had more All-Wild Type (WT), KRAS MT, and NRAS MT tumors vs. MSI-H pts. (42.1% vs. 21.1%; 39.8% vs. 15.4%; 3.6% vs. 0.7%; p&lt;0.001 for each). BRAF MT tumors (95.5% BRAF V600E MT) were more prevalent in MSI-H individuals (62.8% vs. 8.1%, p&lt;0.001). KRAS and BRAF MT tumors were more frequently right-sided, while BRAF MT tumors were associated with female gender, advanced disease stage, lymph node positivity, and poorer differentiation in the MSS subset (p&lt;0.001). Common KRAS mutations included p.G12D (30.44%) and p.G12V (21.3%) in MSS and p.G13D (28.9%) and p.G12D (22.37%) in MSI-H. NRAS MT tumors were dominated by codon 61 mutations (51.7%). Survival analysis revealed worst prognosis in BRAF MT MSS tumors (DFS: HR 1.74 (95% CI 1.15-2.62, p=0.009; OS: HR 1.61 (95% CI 0.99-2.6), p=0.055). The 3-years DFS and 5-years OS rates were lowest in this subset (61.6% and 57.7% respectively).DiscussionThese findings highlight the complex interplay between molecular subtypes, clinicopathological features, and survival outcomes in early CC. Further research is needed to elucidate underlying mechanisms and develop personalized treatment strategies.
Assessing the needs of grandparents of preterm infants in neonatal intensive care units: a cross-sectional study
Authors: Huang Huamin , Tao Jingyun , Lei Ying , Chen Rui , Fang Haixia 
Published: November 2024

BackgroundGlobally, there is an increasing trend in the incidence of premature births and low birth weight. Neonatal intensive care unit (NICU) care has become indispensable for these newborns. Nevertheless, this mode of care poses substantial economic, psychological, and health challenges to the families of preterm infants. Despite abundant evidence concerning the parents’ needs in the NICU, the needs of grandparents—vital family members—are frequently disregarded. This exploratory study aimed to assess the grandparents’ needs of preterm infants in the NICU, exploring the impact of demographic elements on these needs to offer guidance for clinical care practices.MethodsThis study employed a cross-sectional design and the Chinese version of the NICU Family Needs Inventory (NICU-FNI) to investigate the needs of grandparents. A total of 280 grandparents participated in the study, providing data by completing structured questionnaires related to their demographic profiles and needs. Statistical analyses were utilized to analyze the data, including descriptive statistics, chi-square tests, Pearson’s correlation, and multiple linear regression.ResultsSix items about Assurance emerged as significant among the top 10 important needs, with two items for Information, one for Proximity, and one for Support; among the least important needs, nine items related to Comfort and Support were identified. The subscale “Assurance” achieved the highest mean score of 4.07 ± 0.49, followed by the subscales of “Information” and “Proximity,” registering mean scores of 3.50 ± 0.47 and 3.50 ± 0.46, respectively. This explorative study identified a correlation between the needs for Assurance and employment status, place of residence, gestational age, and birth weight (p &lt; 0.05). Employment status, place of residence, and gestational age were identified as significant correlates for Assurance (p &lt; 0.05).ConclusionThe foremost need identified by grandparents is Assurance of quality care for preterm infants, closely followed by the demand for thorough Information and the ability to be in Proximity to the infant. This exploratory study highlights that mitigating the strain on families with preterm infants, as well as recognizing and meeting the needs of grandparents, is of paramount importance.
An in-depth analysis of factors influencing small-scale cattle farmers’ participation in livestock markets in Western Province of Zambia: navigating challenges and barriers
Authors: Mumba Chisoni , Kasanga Bertha , Mwamba Chisanga T. , Sichilima Timothy , Siankwilimba Enock , Sitali Doreen C. , Munkombwe Joshua , Banda Reuben , Muma John Bwalya 
Published: November 2024

IntroductionsThe low participation of small-scale farmers in livestock markets in sub-Saharan Africa, including Zambia, is a major inhibitor to private sector investment in the livestock subsector. Despite the immense potential of the livestock industry to bolster the economic development of countries in this region, several socioeconomic, environmental, and cultural factors contribute to this hindrance.MethodsThis study was conducted in the Western Province of Zambia and adopted a qualitative research approach to understand the challenges and barriers affecting livestock markets among smallholder cattle farmers. In-depth interviews were conducted with 23 key informants and focus group discussions involving key actors in the dairy and beef value chains. Thematic analysis was employed to analyze the gathered data.ResultsFour themes, including socioeconomic, cultural, market dynamics, and policy and regulatory factors, emerged from this analysis. The sub-themes for socioeconomic factors included access to capital, infrastructure challenges, limited technical knowledge, and inadequate veterinary services. Cultural factors included traditional practices, social norms, and perceptions of livestock, and subthemes for market dynamics included price volatility, lack of market information, and middlemen exploitation. The sub-themes for policy and regulatory factors included policy inconsistencies, land tenure issues, and inadequate government support.ConclusionBy identifying and understanding these factors, policymakers and stakeholders can develop effective and sustainable targeted interventions and policies to encourage smallholder cattle farmers’ participation in the livestock sector.