bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enjoying Machines
Authors: Brown Barry , Juhlin Oskar 
Published: August 2019

An argument that pleasure is a fundamental part of why we use technology, and a framework for understanding the relationship between pleasure and technology.
The dominant feature of modern technology is not how productive it makes us, or how it has revolutionized the workplace, but how enjoyable it is. We take pleasure in our devices, from smartphones to personal computers to televisions. Whole classes of leisure activities rely on technology. How has technology become such an integral part of enjoyment? In this book, Barry Brown and Oskar Juhlin examine the relationship between pleasure and technology, investigating what pleasure and leisure are, how they have come to depend on the many forms of technology, and how we might design technology to support enjoyment. They do this by studying the experience of enjoyment, documenting such activities as computer gameplay, deer hunting, tourism, and television watching. They describe technologies that support these activities, including prototype systems that they themselves developed.
Brown and Juhlin argue that pleasure is fundamentally social in nature. We learn how to enjoy ourselves from others, mastering it as a set of skills. Drawing on their own ethnographic studies and on research from economics, psychology, and philosophy, Brown and Juhlin argue that enjoyment is a key concept in understanding the social world. They propose a framework for the study of enjoyment: the empirical program of enjoyment.
The Shared World
Authors: Seemann Axel 
Published: August 2019

A novel treatment of the capacity for shared attention, joint action, and perceptual common knowledge.
In The Shared World, Axel Seemann offers a new treatment of the capacity to perceive, act on, and know about the world together with others. Seemann argues that creatures capable of joint attention stand in a unique perceptual and epistemic relation to their surroundings; they operate in an environment that they, through their communication with their fellow perceivers, help constitute. Seemann shows that this relation can be marshaled to address a range of questions about the social aspect of the mind and its perceptual and cognitive capacities.

Seemann begins with a conceptual question about a complex kind of sociocognitive phenomenon—perceptual common knowledge—and develops an empirically informed account of the spatial structure of the environment in and about which such knowledge is possible. In the course of his argument, he addresses such topics as demonstrative reference in communication, common knowledge about jointly perceived objects, and spatial awareness in joint perception and action.
Nicotinamide riboside exerts protective effect against aging-induced NAFLD-like hepatic dysfunction in mice
Authors: Han Xue , Bao Xiaogang , Lou Qi , Xie Xian , Zhang Meng , Zhou Shasang , Guo Honggang , Jiang Guojun , Shi Qiaojuan 
Published: August 2019

Background & Aims
Aging is one of the risk factors of non-alcoholic fatty liver disease (NAFLD). Yet, the mechanism underlying the aging-associated NAFLD-like syndrome is not fully understood. Nicotinamide adenine dinucleotide (NAD), a ubiquitous coenzyme, has protective effects against aging. Here, we investigated the actions of NAD precursors nicotinamide riboside (NR) on the development of aging-induced NAFLD.

Methods
NR supplemented food (2.5 g/kg food) was applied to aged mice for three months while normal chow to the other groups. Body weight, food intake, liver weight and fat pat mass were measured. The serum concentrations of lipid content, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and NAD were determined by biochemical assays. Pathological assessment and immunohistochemistry analysis of hepatic tissues were used to evaluate the effect of NR on NAFLD development and inflammatory infiltration.

Results
NR repletion significantly reduced fat pat mass in aged mice, while not altered the body weight, food intake, and liver weight. NR repletion significantly rescued the NAD reduction in aged mice. The total cholesterol and triglyceride levels could be lowered by NR repletion in aged mice. The AST level was also significantly reduced by NR repletion in aged group, while the ALT level lowered but without significance. Notably, moderate NAFLD phenotypes, including steatosis and hepatic fibrosis could be markedly corrected by NR repletion. In addition, Kupffer cells accumulated and inflammatory infiltration could also be remarkably reversed by NR repletion in aged mice.

Conclusion
Aging was associated with NAFLD-like phenotypes in mice, which could be reversed by oral NR repletion. Therefore, oral NR uptake might be a promising strategy to halt the progression of NAFLD.
Family Functioning of People Living with HIV/AIDS Accessing Care at a Nigerian Tertiary Health Centre
Authors: Adesina Stephen Adesope , Amole Isaac Olusayo , Durodola Adewumi Ojeniyi , Awotunde Olufemi Timothy , Olaolorun David Akintayo , Adeniran Adenike , Odeigah Louis O. 
Published: August 2019

Aims: To assess the family functioning and identify its determinants among adult PLWHA at Bowen University Teaching Hospital, Ogbomoso.
Study Design: The study is a descriptive cross-sectional study.
Place and Duration of the Study: The study was conducted in the Antiretroviral (ARV) Clinic of the Bowen University Teaching Hospital, Ogbomoso, Nigeria from January 2014 to March 2014.
Methodology: Sixty-one HIV-infected patients aged 18 years and older were selected using the systematic random sampling. Data were collected using a pre-tested, structured, researcher-administered questionnaire which had a section on respondents’ socio-demographic characteristics and incorporated the General Functioning scale of the Family Assessment Device to assess their family functioning. The data were analysed using SPSS and presented as descriptive and inferential statistics.
Results: The mean age of the 61 respondents was 37.1±8.1 years and 43 (70.5%) of them were females. Most of the respondents were married (65.6%) and the proportion of those with primary education (37.7%) was highest. A mean General Functioning (GF) score of 1.8±0.6 indicated an overall healthy family functioning. The proportion of respondents with healthy family functioning was highest for the married among all marital categories and decreased with increasing level of education. These associations of marital status and level of education with family functioning were statistically significant (P = 0.02 and 0.04, respectively) based on the result of Fisher’s exact test.
Conclusion: The fact that larger proportions of the respondents were married and had low education level was found to have influenced the finding of a high rate of healthy family functioning in this study. Therefore, regular family functioning assessment as part of routine evaluation of PLWHA is suggested, and interventions that can temper the dysfunctional influences of formal education on family functioning should be incorporated into HIV/AIDS care.
AHP Method for Selecting the Best Strategy to Enhance Safety Culture: A Case Study at “XYZ” Company in Qatar
Authors: Hadian Cece , . Kholil , Abdullah Syahfirin 
Published: August 2019

Lack of safety culture awareness in the ambulance services affects not only locally but internationally in different countries, including at "XYZ" a company in Qatar. Many studies mentioned about risks and hazards associated with ambulance services that result from illnesses, accidents, or property damaged because of a lack of safety culture. The results of the safety culture survey in ambulance service of XYZ Company were showing less of commitment and involvement of ambulance personnel to safety 52.6% and less motivation 57.9%. It supports by the achievement of key performance index of ambulance services that was 85 % – 96 % from the target. This paper discussed a strategy to improve safety culture in ambulance services. The authors conducted a research study utilizing the AHP method to select the best approach by following the real condition. This study compares the essential factors in improving safety culture based on eight criteria and three strategies safety climate which the result shows that (a) The commitment of senior management with a value of 0.247 or (247%), and (b) Operational approach strategy with a value of 0.386 or (38.6%), with CR of 0.03 are among the top priorities needed in the operational of ambulance services to run optimally.
Flood Management Model in Digital Era, Using SAST (Strtategic Assumption Surfacing and Testing) and the Exponential Comparison Method (ECM): A Case Study in Jakarta
Authors: . Kholil , Prinajati Diah , Annisari Nikki Astarina 
Published: August 2019

Flooding is a regular annual disaster in Jakarta, especially in December to February. Geographical position of Jakarta which is 40% below sea level, causes flooding not only from rain, but also from rob due to rising sea levels. In the last 5 years the impact of flooding became more serious, leading to economic and human losses.
This study aims to determine the right strategy of flood mitigation by public involvement in the digital era. The method used includes combination of quality input data from experts representing BNPB (National Disaster Agency), Local Goverment, Academics, Community Leaders, Businessmen, and Practitioners, in addition to vulnerable field research. Data analysis uses the ECM (Exponential Comparison Method) and SAST (Strategic Assumption Surfacing and Testing).
The result of the study indicates that the most appropriate strategy to mitigate flood disaster is establishment of “Disaster Information Center” and "Disaster alert groups” involving every stakeholder from the community. Utilization of social media, especially WhatsApp, Facebook, and Instagram has been very helpful to share information of flood, especially how to prepare an emergency action to reduce economic and human losses.
Characteristics of the Exradin W1 scintillator in the magnetic field
Authors: Yoon Jeongmin , Kim Jung‐In , Choi Chang Heon , Park Jong Min 
Published: August 2019

AbstractTo investigate the angular dependency of the W1 scintillator with and without a magnetic field, the beam incidence angles to the detector varied from 0° to 360° at intervals of 30° when the detector was pointed in both the craniocaudal and right‐to‐left directions. The beam incidence angles also varied from 0° to 360° at intervals of 45° when the W1 scintillator was in the anterior‐to‐posterior direction. To investigate the field size dependency of the W1 scintillator with and without a magnetic field, the doses by an identical beam‐on time were measured at various square field sizes and the measured doses were normalized to the dose at the field of 10.5 cm × 10.5 cm (FS10.5). With and without a magnetic field, the deviations of the doses to the dose at the beam incident angle of 0° were always less than 1% regardless of the dosimeter positioning relative to the magnetic field direction. When the field sizes were equal to or less than FS10.5, the differences in the output factors with and without a magnetic field were less than 0.7%. However, those were larger than 1% at fields larger than FS10.5, and up to 3.1%. The W1 scintillator showed no angular dependency to the magnetic field. Differences larger than 1% in the output factors with and without a magnetic field were observed at field sizes larger than 10.5 cm × 10.5 cm.
A group of Brazilian Turner syndrome patients: Better quality of life than the control group
Authors: Reis Carolina T. , Macedo Marina C. , Morcillo André M. , Guerra‐Junior Gil , de Lemos‐Marini Sofia Helena V. 
Published: August 2019

AbstractCurrent literature presents no consensus regarding which aspects influence health‐related quality of life (HRQoL) of women with Turner syndrome (TS). The objective of the present study was to compare HRQoL in the TS and control group, using components and domains of the Medical Outcomes Study 36‐Item Short Form Health Survey (SF‐36). Observational, descriptive, and cross‐sectional study with 44 women with TS aged between 18 and 30 years (TS group) and 44 healthy women of the same age which were sisters, relatives, or friends of the TS group (control group). A registration form and the SF‐36 questionnaire were used to analyze HRQoL in TS in relation to the control group. The TS group presented better scores in the mental component summary and in the role physical, bodily pain, general health, social function, and role emotional domains compared to the control group. This study presented some unexpected results, different from those found in the current literature, showing the possibility of TS patients presenting better coping strategies. It is necessary to develop a specific questionnaire to assess QoL in TS and analyze in great detail which factors may influence the HRQoL of these patients.
Manuka honey sinus irrigations in recalcitrant chronic rhinosinusitis: phase 1 randomized, single‐blinded, placebo‐controlled trial
Authors: Ooi Mian Li , Jothin Arvind , Bennett Catherine , Ooi Eng H. , Vreugde Sarah , Psaltis Alkis J. , Wormald Peter‐John 
Published: August 2019

BackgroundManuka honey (MH) has significant antibiofilm activity in vitro and in vivo against Staphylococcus aureus, methicillin‐resistant S aureus (MRSA), and Pseudomonas aeruginosa. This is the first randomized, single‐blinded, placebo‐controlled phase 1 clinical trial investigating the safety and preliminary efficacy of MH with augmented methylglyoxal (MGO) rinses in recalcitrant chronic rhinosinusitis (CRS).MethodsPatients were included after previously undergoing endoscopic sinus surgery and presenting with signs and symptoms of sinus infection with positive bacterial cultures on sinus swabs. Patients were randomized to receive 14 days of twice‐daily 16.5% MH + 1.3 mg/mL MGO sinonasal rinses and concurrent 10 days of placebo tablets (MH), or 14 days of twice‐daily saline sinonasal rinses and concurrent 10 days of culture‐directed antibiotic therapy (CON). Safety observations included the University of Pennsylvania Smell Identification Test (UPSIT) and adverse‐event (AE) reporting. Efficacy was assessed comparing microbiology results, Lund‐Kennedy scores (LKSs), and symptom scores using the visual analog scale (VAS) and 22‐item Sino‐Nasal Outcome Test (SNOT‐22).ResultsTwenty‐five patients completed the study. MH demonstrated a good safety profile with no major AEs and no changes in UPSIT. Six of 10 (60%) MH patients had a reduction in bacterial culture rate with 1 of 10 of those having negative cultures, compared with 12 of 15 (80%) in the control group with 7 of 15 having negative cultures upon completion of the study.ConclusionThis study concludes that twice‐daily 16.5% MH augmented with 1.3 mg/mL MGO sinonasal rinses alone for 14 days is safe but not superior to culture‐directed oral antibiotics and twice‐daily saline rinses.
Water, an Essential Element for a ZnII‐Catalyzed Asymmetric Quinone Diels‐Alder Reaction: Multi‐Selective Construction of Highly Functionalized cis‐Decalins
Authors: Morimoto Kyosuke , Le Thien Phuc , Manna Sudipta Kumar , Kiran I. N. Chaithanya , Tanaka Shinji , Kitamura Masato 
Published: August 2019

AbstractA ZnII complex of a C2‐chiral bisamidine‐type sp2N bidentate ligand (LR) possessing two dioxolane rings at both ends catalyzes a highly efficient quinone asymmetric Diels‐Alder reaction (qADA) between o‐alkoxy‐p‐benzoquinones and 1‐alkoxy‐1,3‐butadienes to construct highly functionalized chiral cis‐decalins, proceeding in up to a >99:1 enantiomer ratio with a high generality in the presence of H2O (H2O:ZnII=4–6:1). In the absence of water, little reaction occurs. The loading amount of the chiral ligand can be minimized to 0.02 mol % with a higher Zn/LR ratio. This first success is ascribed to a supramolecular 3D arrangement of substrates, in which two protons of an “H2O‐ZnII” reactive species make a linear hydrogen bond network with a dioxolane oxygen atom and one‐point‐binding diene; the ZnII atom captures the electron‐accepting two‐points‐binding quinone fixed on the other dioxolane oxygen atom via an n‐π* attractive interaction. The mechanisms has been supported by 1H NMR study, kinetics, X‐ray crystallographic analyses of the related ZnLR complexes, and ligand and substrate structure‐reactivity‐selectivity relationship.
Fixed bed gasification of corn stover biomass fuel: Egypt as a case study
Authors: El‐Sattar Hoda A. , Kamel Salah , Jurado Francisco 
Published: August 2019

AbstractThis paper focuses on the optimal performance of a small tri‐generation power, heat, and cooling plant, which uses corn stover as the feedstock. First, 100 kg h−1 of the corn stover is converted into syngas by the gasification process, using a downdraft fixed‐bed reactor at gasification temperatures reaching 995 °C and with an oxidant–fuel ratio of 1.65. About 243.18 kg h−1 of product gas mass flow with 4.766 MJ kg−1 of calorific value is supplied to an externally fired gas turbine (EFGT) to convert this fuel to electrical power. It is estimated that the EFGT is capable of producing 70.57 kW of electrical power with a high‐temperature heat exchanger efficiency of 75% and a pressure ratio of 4.84 at a turbine inlet temperature of 875 °C. The absorption refrigeration system is used for the cooling process. The cooling power (ℚ

eva
) of the absorption cooling system is 130.92 kW with a cooling tower temperature of 15 °C and a system performance coefficient (PC) of 0.6. The recovered heat flow to the generator (
ℚ

gen
) and the refrigerating heat flow are 82.62 kWth
and 48.83 kWref
, respectively, with a circulation ratio of 4.07. For the whole system (gasifier, EFGT, and absorption cooling), the gross electrical efficiency (ηnetEL ) is 21.78% and the net thermal efficiency (ηth
) is 47.43% with a system cooling‐to‐power ratio (CPR) of 1.88. The simulation of this system was conducted using Cycle‐Tempo software. © 2019 Society of Chemical Industry and John Wiley & Sons, Ltd
Local average treatment effects estimation via substantive model compatible multiple imputation
Authors: DiazOrdaz Karla , Carpenter James 
Published: August 2019

AbstractNonadherence to assigned treatment is common in randomized controlled trials (RCTs). Recently, there has been increased interest in estimating causal effects of treatment received, for example, the so‐called local average treatment effect (LATE). Instrumental variables (IV) methods can be used for identification, with estimation proceeding either via fully parametric mixture models or two‐stage least squares (TSLS). TSLS is popular but can be problematic for binary outcomes where the estimand of interest is a causal odds ratio. Mixture models are rarely used in practice, perhaps because of their perceived complexity and need for specialist software. Here, we propose using multiple imputation (MI) to impute the latent compliance class appearing in the mixture models. Since such models include an interaction term between the latent compliance class and randomized treatment, we use “substantive model compatible” MI (SMC MIC), which can additionally handle missing data in outcomes and other variables in the model, before fitting the mixture models via maximum likelihood to the MI data sets and combining results via Rubin's rules. We use simulations to compare the performance of SMC MIC to existing approaches and also illustrate the methods by reanalyzing an RCT in UK primary health. We show that SMC MIC can be more efficient than full Bayesian estimation when auxiliary variables are incorporated, and is superior to two‐stage methods, especially for binary outcomes.
Rapid behavioral assay using handling test provides breed and sex differences in tameness of chickens
Authors: Moroi Saki , Nishimura Kenji , Imai Nana , Kunishige Kyoko , Sato Shun , Goto Tatsuhiko 
Published: August 2019

AbstractBackgroundJapanese indigenous chicken breeds are often used to improve meat quality rather than broilers in the Jidori industry. There are sometimes severe crowding accidents caused by many birds frightened by environmental stimuli. To prevent the economic loss, the chickens need to be more gentle, tame, and imperturbable.MethodsIn this study, a new handling test for tameness in adult chickens in individual cages was performed with 100 birds from each sex of Shamo, Rhode Island Red, Nagoya, Australorp, and Ukokkei, as well as 10 hens of F1 hybrid between Shamo and Rhode Island Red, to measure both active and passive tameness. We counted the number heading toward human hands (heading) and retreating in other directions (avoiding) in both active and passive tameness phases, as well as the number of steps taken (step) during the handling test.ResultsMale chickens exhibited higher avoidance behavior than females. Nagoya females displayed the lowest level of avoidance behavior, which implies passive tameness. In terms of active tameness, a variety of phenotypes can be obtained in different combinations of breed and sex. These results suggested the handling test will be good method for rapid screening of individual differences in tameness. In addition, there were heterosis effects on avoidance and locomotive behaviors. Since F1 is often used in the Jidori industry, the breeders should be tested not only for meat production but also for tameness.ConclusionsIn the future, combining both the behavioral screening and the population genomics will establish typical evidence about mechanisms of tameness and domestication in animals.
The role of environmental innovation through the technological proximity in the implementation of the sustainable development
Authors: Aldieri Luigi , Kotsemir Maxim , Vinci Concetto Paolo 
Published: August 2019

AbstractThis paper explores the relationship between a firm's knowledge sourcing strategy and green innovation. The data are taken from Organisation for Economic Cooperation and Development REGPAT database, February 2016, relative to the European Patent Office firms' patent applications published up to December 2015. The study contributes to the literature by focusing on the moderating role of integration between different activities related to environmental performance on the relationship between knowledge sources and green innovations. The results from 240 firms indicate a shift in the focus from internal knowledge to external knowledge when developing environmental innovations. Government policies promoting more knowledge complementarity and coordination between environmental fields will help to promote more knowledge transfer, allowing more sustainable development.
Phage display as a tool for vaccine and immunotherapy development
Authors: Hess Krystina L. , Jewell Christopher M. 
Published: August 2019

AbstractBacteriophages, or phages, are viruses that specifically infect bacteria and coopt the cellular machinery to create more phage proteins, eventually resulting in the release of new phage particles. Phages are heavily utilized in bioengineering for applications ranging from tissue engineering scaffolds to immune signal delivery. Of specific interest to vaccines and immunotherapies, phages have demonstrated an ability to activate both the innate and adaptive immune systems. The genome of these viral particles can be harnessed for DNA vaccination, or the surface proteins can be exploited for antigen display. More specifically, genes that encode an antigen of interest can be spliced into the phage genome, allowing antigenic proteins or peptides to be displayed by fusion to phage capsid proteins. Phages therefore present antigens to immune cells in a highly ordered and repetitive manner. This review discusses the use of phage with adjuvanting activity as antigen delivery vehicles for vaccination against infectious disease and cancer.