bluuebunny/crossref_metadata_2025_split huggingface dataset:
L’adaptation de la pratique des sportifs du grand âge : objet de négociations
Authors: Hénaff-Pineau Pia-Caroline 
Published: June 2018

Le nouveau modèle médico-social du « bien vieillir » préconisé aux seniors invite à vieillir en restant actif et place l’activité physique au cœur des politiques de santé et de prévention du vieillissement. Si la pratique physique et/ou sportive est prônée comme action fortifiante ralentissant les effets délétères du vieillissement, elle représente aussi un risque potentiel d’accidents susceptibles de fragiliser la personne âgée. Ainsi, le choix de l’activité et des conditions de l’exercice physique constitue un point sensible de la pratique physique du senior. Dans cet article, nous montrerons que la définition de la pratique sportive adaptée à l’avancée vers le grand âge est l’objet de négociations plurielles entre le senior et des « autrui significatifs », notamment le premier cercle familial, les enfants et le (la) conjoint(e), mais aussi entre le senior et le médecin généraliste auquel est attribué un rôle amplifié depuis une dizaine d’années dans la promotion et la prescription d’activités physiques. Nous verrons qu’avec l’avancée en âge les demandes d’adaptation de la pratique, les conseils en faveur de la modération, se multiplient. Sont alors prioritairement perçus la fragilité du senior vieillissant et donc les dangers plus que les bénéfices de la pratique sportive. Les adaptations résultent d’arrangements entre conseils des uns, exhortations des autres et sensations des sportifs. Cependant, lorsque les compétiteurs du grand âge détiennent des performances exceptionnelles, alors les risques de la pratique et les adaptations semblent ignorés de tous.
Motivation des personnes âgées à pratiquer une activité physique
Authors: Maillot Pauline , Becquard Clémentine , Perrot Alexandra 
Published: June 2018

Alors que les bénéfices d’une activité physique régulière sur la santé ne sont plus à démontrer, la non-pratique d’activité physique est un phénomène exponentiel avec l’avancée en âge, avec une rupture non négligeable à partir de 70 ans. Afin de mieux comprendre l’engagement et la persévérance dans les activités physiques avec l’âge, cette étude propose de s’intéresser aux motivations et aux raisons de pratiquer qui régissent les comportements des personnes âgées qui se déclarent actives. Pour cela, elle se base sur la Théorie de l’AutoDétermination (TAD) permettant d’évaluer le degré d’autodétermination des individus envers un comportement (i.e., degré d’adoption volontaire) et sur l’importance des motifs de participation à l’activité physique. Ce travail vise alors à étudier la contribution des raisons à pratiquer (via le questionnaire EMI-2) sur l’Indice d’Autonomie Relative (IAR : score d’autodétermination issu du questionnaire BREQ-3) selon deux groupes de personnes âgées (60-70 vs. 71-90). Les résultats soulignent l’importance de la dimension plaisir dans la pratique physique régulière des seniors, et d’autant plus à partir de 70 ans.
Les modes de vie dans les ensembles résidentiels pour personnes âgées autonomes
Authors: Bacconnier-Baylet Sandrine , Chaudet Béatrice , Madoré François 
Published: June 2018

L’objet de cet article est de mieux comprendre les raisons de l’emménagement des seniors dans des Ensembles résidentiels pour personnes âgées autonomes (ERPAA) ainsi que leurs modes de vie. Il est indispensable dans un premier temps de définir ces ERPAA, en montrant leur diversité typologique et leur inégale inscription territoriale. Une triple interrogation structurera ensuite le propos : pour quelles raisons les résidents de ces ERPAA ont-ils fait ce choix résidentiel et, une fois installés, que font-ils ici et quelles sont leurs pratiques spatiales ? Notre contribution s’appuiera sur les résultats d’un programme de recherche intitulé « Longévité, Mobilité et Autonomie » (LMA) financé par la région des Pays de la Loire. En termes de méthodologie, nous mobiliserons : une base de données permettant de recenser les ERPAA en Pays de la Loire ; les résultats de focus group ayant impliqué 52 résidents de sept complexes résidentiels (trois résidences services, un village seniors, une résidence autonomie, une Marpa et un Domicile services appartenant à une société mutualiste) ; les entretiens auprès de promoteurs et/ou gestionnaires de ces ERPAA.
L’industrialisation de la médecine libérale : une approche par l’Économie des conventions
Authors: Da Silva Nicolas 
Published: June 2018

Cet article propose d’analyser l’industrialisation de la médecine libérale à partir du cadre théorique de l’économie des conventions. L’industrialisation du secteur se donne à voir à travers les réformes visant à réguler les pratiques médicales autour du respect de standards quantifiés de qualité des soins. Tout se passe comme si le soin était un produit homogène facilement réplicable d’un patient à un autre, indépendamment de leurs singularités. Plutôt que de considérer ce mouvement comme une « rationalisation », nous montrons qu’il s’agit d’une modification de la convention de qualité des soins médicaux – d’une convention inspirée/domestique à une convention industrielle. Également légitimes, la délibération ou le compromis entre ces deux conventions devraient faire l’objet d’un débat politique, ce qui n’est pas le cas. Pis, dans le contexte actuel, il est fort probable que l’industrialisation des soins, qui est une réponse à des critiques légitimes de la convention inspirée/domestique, devienne un accélérateur de la marchandisation des soins – celle-ci étant néfaste tant pour les malades que pour les professionnels.
Formulation et mise en œuvre d’une stratégie logistique hospitalière : un exemple d’industrialisation
Authors: Landry Sylvain , Beaulieu Martin 
Published: June 2018

La « logistique hospitalière » est l’expression utilisée pour désigner la gestion des différents réseaux de distribution internes qui soutiennent la prestation de soins avec différents produits, fournitures et équipements. Cet article entend discuter des défis de la formulation et de la mise en œuvre d’une stratégie logistique dans un milieu comme celui de la santé où les activités logistiques demeurent en périphérie de la mission première de l’organisation. Pour ce faire, cet article retrace certains emprunts du milieu de la santé au secteur manufacturier afin de définir les structures de gestion de la logistique hospitalière et certains des outils qui sont utilisés pour gérer les stocks d’un hôpital. L’article montre que la mise en œuvre d’une stratégie logistique dans un centre hospitalier a avantage à s’inspirer sur une démarche de Lean management qui constitue lui-même un autre exemple d’emprunt au secteur industriel.
THROMBOCYTOPENIA IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES - STILL AN UNSOLVED PROBLEM
Authors: Basood May , Oster Howard S. , Mittelman Moshe 
Published: June 2018

The myelodysplastic syndromes (MDS) are a group of clonal bone marrow (BM) stem cell disorders, characterized by ineffective hematopoiesis, peripheral cytopenias and hematologic cellular dysfunction, as well as potential transformation to acute leukemia.Thrombocytopenia is common in MDS and is associated with bleeding complications, occasionally life threatening. Low platelet count (PLT), as well declining PLT also serves as a prognostic marker. Understanding thrombopoiesis led to the cloning of thrombopoietin, resulting in the development of platelet stimulating agents, thrombomimetics, romiplostim and eltrombopag.Both agents have been shown to increase PLT, decrease the need for platelet transfusions and reduce the number of bleeding episodes, with a reasonable tolerance. They are already approved for immune thrombocytopenia and thrombocytopenia related to liver disease.Romiplostim and eltrombopag have proven efficacy in lower- and higher-risk MDS with thrombocytopenia, as monotherapy, as well as a part of a combination, either with lenalidomide, and mainly combined with hypomethylating agents. However, safety concerns have been raised: while several trials have been completed with no evidence of disease progression, others have been early terminated due to increased number of BM blasts and possible leukemic transformation in treated-patients. The jury is still out regarding this safety concern, although recent publications are more encouraging. Keywords: Myelodysplastic syndrome, Thrombocytopenia, Thrombomimetics,Romiplostim, Eltrombopag.
Crystal structure of (2E)-1-(4-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
Authors: Yesilyurt Fatma , Aydin Abdullah , Gul Halise Inci , Akkurt Mehmet , Ozcelik Nefise Dilek 
Published: June 2018

The compound, C16H14O3, (except H atoms) is almost planar [r.m.s. deviations for all non-H atoms = 0.001 Å] and the dihedral angle between the aromatic rings is 9.35 (7)°. In the crystal, molecules are linked by intermolecular O—H···O and C—H···O hydrogen bonds, forming a three-dimensional network structure. Furthermore, a weak π-π stacking interactions [centroid-to-centroid distance = 3.7055 (9) Å] contributes to the stabilization of the molecular packing. Crystal Data for C16H14O3 (M = 254.27 g/mol): Orthorhombic, space group Pbca (no. 61), a = 13.4563(16) Å, b = 11.4986(14) Å, c = 16.720(2) Å, V = 2587.1(5) Å3, Z = 8, T = 296(2) K, μ(MoKα) = 0.090 mm-1, Dcalc = 1.306 g/cm3, 61402 reflections measured (4.88° ≤ 2Θ ≤ 56.76°), 3240 unique (Rint = 0.0334, Rsigma = 0.0120) which were used in all calculations. The final R1 was 0.0438 (I≥2σ(I)) and wR2 was 0.1228 (all data).
Politie en krijgsmacht samen in speciale eenheden voor de politietaak
Authors: Timmer Jaap 
Published: June 2018

Police and army cooperating in Special Units
Since 2006 the police and the army in the Netherlands cooperate within the System of Special Units. These units are called upon in life-threatening situations with imminent or actual severe violence related for example to organized crime or terrorism. The author examines this cooperation and its added value. The work of the special units system in the police organization should be viewed and treated as police work. Considering today’s concerns about terrorism, it seems wise to invest in an adequate anti-terrorism capacity. Yet the reality is that there are far fewer terrorist attacks and victims in the Netherlands now than in the 1970s. At the same time the number of arrests under life-threatening circumstances that are dealt with by the Arrest Team (SWAT) within the police organization is much higher nowadays. The SWAT lacks capacity to deal with this situation adequately.
Hybridisering van de zwaardmachten: realiteit of fictie?
Authors: Neuteboom Peter , Hovens Hans 
Published: June 2018

The police and the army as hybrid organizations: reality or fiction?
National and international security are becoming increasingly interdependent. The question is whether this leads to a certain level of militarization of the police and constibularisation of the military. In some of their operations and units, the Dutch police apply tactics, technologies and organizational principles that resemble those of the military. The police also contribute to international peace support operations and stability missions to train or monitor police in post-conflict areas. The Dutch army has been involved in some sort of interim policing during several stability missions and increasingly support the Dutch police in law enforcement operations by providing search and analytical support. Finally, as a police force with a military status, the Royal Marechaussee has acquired a structural and strong position in the Dutch police system. Although there is some sort of convergence, the authors conclude that the level of militarization of the police and constabularisation of the military remains limited.
Krijger als opsporingsambtenaar?
Authors: Voetelink Joop 
Published: June 2018

On warriors acting as investigation officers
The Netherlands armed forces are increasingly involved in activities within the Netherlands as well as abroad, that can be characterized as law enforcement. Military personnel, however, are not trained as law enforcement officials and perform these non-military tasks based on their military skills and drills. Nevertheless, their efforts eventually must lead to a criminal persecution of a suspect. Therefore, it is important that military personnel are well aware of the particular requirements set out by criminal procedures while planning and executing a military action and, whenever possible, operate in close collaboration with authorized law enforcement officials.
Re-inventando(nos)
Authors: Martínez Morales María , Bermúdez Vázquez Virginia 
Published: July 2018

El presente artículo da cuenta de una investigación a/r/tográfica llevada a cabo con una comunidad de inmigrantes como acción artística colectiva. Es un proyecto basado en la construcción de una Web como dispositivo activador de las situaciones y discursos derivados del propio proceso de creación artística. De esta manera, el artículo se organiza según una introducción en la que justificamos el interés que nos lleva a considerar necesaria la propuesta de investigación a/r/tográfica. A continuación, sigue un apartado donde analizamos el papel del medio digital como herramienta de comunicación y agencia vinculada con esta experiencia de investigación. En el siguiente punto damos cuenta del proceso investigativo describiendo el enfoque metodológico llevado a cabo, el diseño de la propuesta de investigación a/r/tográfica y las acciones desarrolladas basadas en la práctica artística colectiva. Finalmente, a modo de conclusión, exponemos un apartado elaborado a partir de la puesta en común con el colectivo y las reflexiones y pensamientos que se derivan del proceso creativo como eje vertebrador de la acción con la comunidad. Quedando manifestada, por tanto, la importancia del proceso colectivo basado no solamente en la acción artística como forma de conocimiento sino también como aprendizaje y comprensión de una realidad social en la que quedamos sumergidas.
Childhood Community Disadvantage and MRI-Derived Structural Brain Integrity After Age 65 Years
Authors: Peterson Rachel L. , Meza Erika , George Kristen M. , Maillard Pauline , DeCarli Charles , Gilsanz Paola , Soh Yenee , Lor Yi , Kind Amy J. , Barnes Lisa L. , Whitmer Rachel A. 
Published: November 2024

ImportancePrior studies associate late-life community disadvantage with worse brain health. It is relatively unknown if childhood community disadvantage associates with late-life brain health.ObjectiveTo test associations between childhood residence in an economically disadvantaged community, individual income and education, and late-life cortical brain volumes and white matter integrity.Design, Setting, and ParticipantsThis cohort study was conducted in the ongoing harmonized cohorts KHANDLE (Kaiser Healthy Aging and Diverse Life Experiences Study; initiated 2017) and STAR (Study of Healthy Aging in African Americans; initiated 2018) using all available data collected out of a regional integrated health care delivery network in California between cohort initiation and analysis initiation in June 2023. Eligible participants were Kaiser Permanente Northern California member ages 65 years or older. Data were analyzed between June and November 2023.ExposureResidence at birth was geocoded and linked to historical Area Deprivation Indices (ADI). ADI is a nationally ranked percentile; community disadvantage was defined as ADI of 80 or higher.Main Outcomes and MeasuresRegional brain volumes and white matter integrity measures were derived from a random subset of participants who underwent 3T magnetic resonance imaging. Models adjusted for race and ethnicity, sex, and parental education.ResultsOf a total 2161 individuals in the combined cohort, 443 individuals were eligible for imaging (mean [SD] age, 76.3 [6.5] years; 253 female [57.1%]; 56 Asian [12.6%], 212 Black [47.9%], 67 Latino [15.1%], 109 White [24.6%]). Imaging participants had a mean (SD) 15.0 (2.5) years of education, and 183 (41.3%) earned $55 000 to $99 999 annually. Fifty-four participants (12.2%) resided in a disadvantaged childhood community. Childhood community disadvantage was associated with smaller gray matter volumes overall (−0.39 cm3; 95% CI, −0.65 to −0.10 cm3) and in the cerebellum (−0.39 cm3; 95% CI, −0.66 to −0.09 cm3), hippocampus (−0.37 cm3; 95% CI, −0.68 to −0.04 cm3), and parietal cortex (−0.25 cm3; 95% CI, −0.46 to −0.04 cm3) and larger mean lateral ventricle (0.44 cm3; 95% CI, 0.12 to 0.74 cm3), third ventricle (0.28 cm3; 95% CI, 0.03 to 0.55 cm3), and white matter hyperintensity volume (0.31 cm3; 95% CI, 0.06 to 0.56 cm3). Educational attainment and late-life income did not mediate these associations.Conclusions and RelevanceIn this cohort study of racially and ethnically diverse health plan members, childhood community disadvantage was associated with worse late-life brain health independent of individual socioeconomic status. Future work should explore alternative pathways (eg, cardiovascular health) that may explain observed associations.
Polygenic Risk Scores and Hearing Loss Phenotypes in Children
Authors: Wang Jing , He Fan , Shepherd Daisy A. , Li Shuai , Lange Katherine , Sung Valerie , Morgan Angela , Kerr Jessica A. , Saffery Richard , Wake Melissa 
Published: November 2024

ImportanceMonogenic causes of childhood hearing loss are well established, as are polygenic risk contributions to age-related hearing loss. However, an untested possibility is that polygenic risk scores (PRS) also contribute to childhood hearing loss of all severities, alongside environmental and/or monogenic causes.ObjectiveTo examine the association between a PRS for adult hearing loss and childhood hearing loss phenotypes.Design, Setting, and ParticipantsThis cross-sectional study used a unique population-based dataset spanning normal hearing to profound loss, combining 2 contemporaneous population cohorts in Australia. This included the Child Health CheckPoint, a national population-based cross-sectional study nested within the Longitudinal Study of Australian Children, and the Victorian Childhood Hearing Longitudinal Databank (VicCHILD), a statewide population-based longitudinal data bank open to every child with congenital hearing loss in Victoria, Australia. The analysis took place from March to August 2023.ExposuresGenotype data were generated from saliva- or blood-derived DNA using global single-nucleotide variations arrays. Based on genotype data, PRS was computed using published UK Biobank genome-wide association study results for self-reported hearing difficulty in individuals aged 40 to 69 years.Main Outcomes and MeasuresHearing outcomes were classified by laterality (bilateral, unilateral), severity (mild, moderate, severe or worse) and types (sensorineural, conductive, mixed, auditory neuropathy, atresia). Analyses included multinominal logistic regressions of PRS with hearing outcomes.ResultsOverall, 1488 CheckPoint study children (49.8% boys, aged 11-12 years) and 527 VicCHILD study children (55.2% boys, aged 0-13 years) with hearing and genotype data were included. A 1-SD increment in PRS was associated with higher odds of mild (odds ratio [OR], 1.3; 95% CI, 1.0-1.6), moderate (OR, 5.1; 95% CI, 3.2-8.1), and severe or worse (OR, 5.3; 95% CI, 3.9-7.3) unilateral hearing loss compared with normal hearing. Similarly, the PRS was associated with increased odds of mild, moderate, and severe or worse bilateral hearing loss (per-SD ORs, 3.9-6.6) and all hearing loss types (per-SD ORs, 8.5-10.6).Conclusions and RelevanceIn this cross-sectional study, a PRS initially developed for adult hearing difficulty was associated with wide-ranging childhood hearing loss phenotypes, partly explaining hearing phenotype variations despite shared genetic and environmental factors (eg, preterm birth). Large-scale studies with objectively defined hearing phenotypes are crucial for refining PRS and predicting high-risk children.
Spontaneous Corrosion Induced Scalable Fabrication of Bayberry‐Like Ni@Ni3S2 Core–Shell Catalysts for 5‐Hydroxymethylfurfural Oxidation
Authors: Chen Ye , Qiu Jiayao , Li Shilong , Zhang Jingru , Liu Yi , Chen Xin , Liu Xupo , Dou Shixue , Wang Deli 
Published: November 2024

AbstractElectrocatalytic oxidation of biomass‐derived 5‐hydroxymethylfurfural (HMF) presents a promising pathway for synthesizing the value‐added chemical, 2,5‐furandicarboxylic acid (FDCA). However, it is still lack of scalable strategies to fabricate electrocatalysts with high activity and selectivity. Herein, a bayberry‐like Ni@Ni3S2 core–shell catalyst is prepared via a spontaneous corrosion strategy for HMF electro‐oxidation. The Ni3S2 shells with abundant electron‐deficient Ni sites facilitate the generation of high‐valence Ni3+OOH active species. Additionally, the in situ oxidation of S2− to SO42− enhances the electron and proton transport capacity. Both high‐performance liquid chromatography (HPLC) and density functional theory (DFT) analyses reveal that Ni@Ni3S2 preferentially selects the 2,5‐dicarboxyfurylfuran (DFF) pathway due to the lower reaction energy barrier from HMF to DFF, and the rate‐determining step of DFF oxidation to generate 5‐formylfuran‐2‐carboxylic acid (FFCA) is significantly accelerated. Consequently, the yield of FDCA and Faraday efficiency are found to be 99.20% and 99.35%, respectively, and they still reach 88.79% and 90.33% after ten cycles, showing excellent stability. Moreover, a mass production of 13.97 g Ni@Ni3S2 is successfully synthesized using the spontaneous corrosion strategy. This work offers a valuable reference for designing scalable and high‐performance catalysts by manipulating reaction routes to achieve efficient biomass conversion.
Progress and Perspective of High‐Entropy Strategy Applied in Layered Transition Metal Oxide Cathode Materials for High‐Energy and Long Cycle Life Sodium‐Ion Batteries
Authors: Wang Lei , Wang Leilei , Wang Haichao , Dong Hanghang , Sun Weiwei , Lv Li‐Ping , Yang Chao , Xiao Yao , Wu Feixiang , Wang Yong , Chou Shulei , Sun Bing , Wang Guoxiu , Chen Shuangqiang 
Published: November 2024

AbstractLayered transition metal oxide (LTMO) cathode materials of sodium‐ion batteries (SIBs) have shown great potential in large‐scale energy storage applications owing to their distinctive periodic layered structure and 2D ion diffusion channels. However, several challenges have hindered their widespread application, including phase transition complexities, interface instability, and susceptibility to air exposure. Fortunately, an impactful solution has emerged in the form of a high‐entropy doping strategy employed in energy storage research. Through the implementation of high‐entropy doping, LTMOs can overcome the aforementioned limitations, thereby elevating LTMO materials to a highly competitive and attractive option for next‐generation cathodes of SIBs. Thus, a comprehensive overview of the origins, definition, and characteristics of high‐entropy doping is provided. Additionally, the challenges associated with LTMOs in SIBs are explored, and discussed various modification methods to address these challenges. This review places significant emphasis on conducting a thorough analysis of the research advancements about high‐entropy LTMOs utilized in SIBs. Furthermore, a meticulous assessment of the future development trajectory is undertaken, heralding valuable research insights for the design and synthesis of advanced energy storage materials.