bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying New High-confidence Polluted White Dwarf Candidates Using Gaia XP Spectra and Self-organizing Maps
Authors: Pérez-Couto Xabier , Pallas-Quintela Lara , Manteiga Minia , Villaver Eva , Dafonte Carlos 
Published: November 2024

Abstract
The identification of new white dwarfs (WDs) polluted with heavy elements is important since they provide a valuable tool for inferring the chemical properties of putative planetary systems accreting material on their surfaces. The Gaia space mission has provided us with an unprecedented amount of astrometric, photometric, and low-resolution (XP) spectroscopic data for millions of newly discovered stellar sources, among them thousands of WDs. In order to find WDs among these data and to identify which ones have metals in their atmospheres, we propose a methodology based on an unsupervised artificial intelligence technique called self-organizing maps. In our approach, a nonlinear high-dimensional data set is projected on a 2D grid map where similar elements fall into the same neuron. By applying this method, we obtained a clean sample of 66,337 WDs. We performed an automatic spectral classification analysis on them, obtaining 143 bona fide polluted WD candidates not previously classified in the literature. The majority of them are cool WDs and we identify in their XP spectra several metallic lines such as Ca, Mg, Na, Li, and K. The fact that we obtain similar precision metrics to those achieved with recent supervised techniques highlights the power of our unsupervised approach to mine the Gaia archives for hidden treasures to follow up spectroscopically with higher resolution.
21cmlstm: A Fast Memory-based Emulator of the Global 21 cm Signal with Unprecedented Accuracy
Authors: Dorigo Jones J. , Bahauddin S. M. , Rapetti D. , Mirocha J. , Burns J. O. 
Published: November 2024

Abstract
Neural network (NN) emulators of the global 21 cm signal need an emulation error much less than the observational noise in order to be used to perform unbiased Bayesian parameter inference. To this end, we introduce 21cmLSTM—a long short-term memory (LSTM) NN emulator of the global 21 cm signal that leverages the intrinsic correlation between frequency channels to achieve exceptional accuracy compared to previous emulators, which are all feedforward, fully connected NNs. LSTM NNs are a type of recurrent NN designed to capture long-term dependencies in sequential data. When trained and tested on the same simulated set of global 21 cm signals as the best previous emulators, 21cmLSTM has an average relative rms error of 0.22%—equivalently 0.39 mK—and comparably fast evaluation time. We perform seven-dimensional Bayesian parameter estimation analyses using 21cmLSTM to fit global 21 cm signal mock data with different adopted observational noise levels, σ
21. The posterior 1σ rms error is ≈three times less than σ
21 for each fit and consistently decreases for tighter noise levels, showing that 21cmLSTM can sufficiently exploit even very optimistic measurements of the global 21 cm signal. We have made the emulator, code, and data sets publicly available so that 21cmLSTM can be independently tested and used to retrain and constrain other 21 cm models.
Pour une écriture écologique dans le diptyque Rue des Perplexes et Quand passent les âmes errantes du romancier algérien Mohamed Magani
Authors: Benaid Malki 
Published: November 2024

Nous vivons dans l’ère de « l’anthropocène », concept mis au goût du jour par les humanités environnementales pour signifier que l’homme n’est plus « la mesure et le centre de toute chose », comme le prônait Protagoras, mais un élément, déterminant et, surtout, redoutable, d’un vaste biotope. En effet, si les autres éléments de ce système fonctionnaient spontanément dans l’harmonie, les comportements déplacés de l’Homo Sapiens, depuis le néolithique jusqu’à l’ère contemporaine, ont perturbé, et à tout jamais, l’équilibre de ce système symbiotique : réchauffement climatique dû à l’émission des gaz à effet de serre, tarissement des ressources naturelles, causé par leur surexploitation, extermination progressive de la faune et de la flore sauvages… Ipso facto, il s’est avéré que l’homme n’est en fait qu’un être situé au milieu du monde, un vivant parmi les vivants, et non plus l’être « privilégié » de jadis, puisque doué de logos et d’intelligence, placé ainsi qu’il le croyait au centre du monde et à la tête de la pyramide des vivants. Dans une telle situation de vulnérabilité, les sonnettes d’alarmes ont déjà été lancées et les enjeux environnementaux se sont affirmés comme des thèmes centraux dans la réflexion artistique contemporaine, notamment dans la réflexion littéraire, où ils s’imposent en tant que schèmes discursifs prépondérants. Ipso facto, la littérature s’engage, à sa manière, dans le combat écologique avec les moyens qui sont mis à sa disposition. Pour illustrer l’orientation écocentrée de l’écriture contemporaine, nous avons choisi d’analyser le diptyque Rue des Perplexes et Quand passent les âmes errantes de Mohamed Magani sous l’angle respectif d’une double lecture écopoétique et zoopoétique. L’auteur iconoclaste algérien en question a, en effet, osé s’aventurer, sur le terrain encore vierge en Algérie, celui de l’écriture environnementale.
Tradition et idéalité
Authors: Salanskis Jean-Michel 
Published: November 2024

L’article réfléchit sur la vision husserlienne, dans notre texte, de la tradition et de l’idéalité. Pour Husserl, une question en retour doit récupérer le sens intentionnel idéal du géométrique aperçu par les fondateurs Grecs. Il voit la transmission du sens comme conduisant au présent à une désédimentation.J’expose dans l’article la conception de la transmission du sens mathématique proposée dans mon ouvrage L’herméneutique formelle (1991/2013). Je rapporte les résultats de cette approche concernant l’espace : mon livre envisage plutôt un devenir méconnaissable du sens géométrique. Je commente alors le traitement par Husserl de la notion d’idéalité. Je distingue les notions symboliques, métaphysiques et téléologiques de l’idéalité, et j’analyse leur usage par Husserl, sans dégager de conclusion univoque.
‘Justice be with you’: Transcending the peace talk rhetoric in the Zion Christian Church
Authors: Kgatle Mookgo S. 
Published: November 2024

The Zion Christian Church is one of the largest, most powerful and influential African Independent Churches (AICs). Its membership of about 6 million makes up about 50% of the total membership of AICs. The church has been preaching peace from its inception which became one of the cores of its theology and practice. Thus, the church is known for its peace talk rhetoric expressed in Northern Sotho, ‘Kgotso ebe le lena’ which means ‘Peace be with you’ or even ‘kgotso ebe le batho’ which means ‘peace be with the people’. This peace talk rhetoric is usually used by the church’s leaders and the church’s ordinary members. Through this rhetoric, the church played a meaningful role in moving South Africa towards peace and reconciliation in 1994. This article argues that the theology of peace and reconciliation should be constructed by transcending the peace talk rhetoric to meaningful works of justice. The wrongs of the past should be corrected rather than just a mere talk about peace. The theology of peace and reconciliation should not only be a ‘peace be with you’ rhetoric but also a ‘justice be with you’. The reviewed literature in this article focussed on peace and reconciliation in the Zion Christian Church, peace talks and peace theology. A case study method was used for the selection of the Zion Christian Church.Contribution: The theology of peace and reconciliation is discussed by incorporating justice in addition to the peace talk rhetoric in the Zion Christian Church.
Diversity in the Clinical Course and Outcome of COVID-19 in Patients with Different Inborn Errors of Immunity can be Associated with the Type of Error
Authors: Salemi Negin , Shojaie Behrokh , Bolourinejad Paria , Sherkat Roya , Zamanifar Aryana , Ghaedrahmati Farhoodeh , Azizi Mahdieh , Aria Hamid 
Published: November 2024

Background:
The relationship between inborn errors of immunity (IEIs) and COVID-19 severity and incidence rates remains unclear due to limited and diverse data. This study aimed to address this gap by identifying specific IEIs associated with an increased risk of severe COVID-19 or a predisposition to severe disease before vaccination.

Materials and Methods:
Data were collected from the medical records of 15 patients with various IEIs, supplemented by interviews with individuals from an IEIs registry who had experienced COVID-19 before vaccination.

Results:
Among the participants, only three patients (20%) experienced severe-prolonged COVID-19. Notably, this severity was predominantly observed in two male patients with Bruton’s disease (BD) and one female patient with autosomal recessive hypogammaglobinemia. Moderate and severe COVID-19 cases were equally distributed (13.33%). In the female subgroup, one patient with common variable immunodeficiency and another with combined immunodeficiency experienced moderate and severe COVID-19, respectively. Conversely, both male patients with moderate and severe COVID-19 had BD.

Conclusion:
Despite the limited number of severe cases, the absence of cytokine storm manifestation suggests potential protective mechanisms, possibly due to intravenous immunoglobulin therapy and inherent deficiencies within cytokine-producing cells (B and T cells). While IEIs may not be significant risk factors for COVID-19, they offer promising avenues for further research into therapeutic strategies targeting specific immune system components to mitigate severe COVID-19.
Investigating the Effect of Galbanic Acid on Lipin-1 and Lipin-2 Genes in Fatty Liver Cells with Palmitate
Authors: Musavi Hadis , Iraie Reza , Mohammadi Maryam , Barartabar Zeinab , Yazdi Mohammad , Bagheri Abouzar , Khonakdar-Tarsi Abbas 
Published: November 2024

Background:
Non-alcoholic fatty liver disease is related to lipid accumulation and inflammation. Considering the role of lipin-1 and lipin-2 in fat homeostasis and inflammation, this study aimed to explore the effect of galbanic acid (Gal) and resveratrol (RSV) on alterations in the gene expression levels and protein abundance of lipin-1 and lipin-2 in HepG2 liver cells lipid-enriched with palmitate (Pal).

Materials and Methods:
HepG2 cells were subjected to different amounts of Gal and RSV for 24 hours in the presence of Pal to induce lipid accumulation. The RT-PCR method was employed to assess the expression of lipin-1 and lipin-2 genes, while protein levels were evaluated by western blot analysis. Lipid accumulation was determined qualitatively and semi-quantitatively using the oil-red staining technique.

Results:
Gal treatment increased lipin-1 and lipin-2 gene expression (P < 0.05). In contrast, the groups treated with RSV did not show a substantial variance in the expression levels of the two genes (P > 0.05). In the groups treated with Gal/RSV, the intensity of lipin-2 protein bands was higher compared to the Pal group (P > 0.01); however, the intensity of lipin-1 protein bands was not significantly different (P > 0.05).

Conclusion:
Gal, a coumarin compound, significantly increased the expression of lipin-1 and lipin-2 in HepG2 cells treated with Pal. Consequently, this research suggests gal as a novel strategy for regulating fat homeostasis in HepG2 cells.
TNF-α-Induced NF-κB Alter the Methylation Status of Some Stemness Genes in HT-29 Human Colon Cancer Cell
Authors: Zand Hamid , Hosseini Seyed Ahmad , Cheraghpour Makan , Alipour Meysam , Sedaghat Fatemeh 
Published: November 2024

Background:
Acquisition of stem-like properties requires overcoming the epigenetic barrier of differentiation and re-expression of several genes involved in stemness and the cell cycle. DNA methylation is the classic epigenetic mechanism for de/differentiation. The writers and erasers of DNA methylation are not site-specific enzymes for altering specific gene methylation. Thus, the aim of the present study is investigation of the in vitro interaction of ten eleven translocations (TETs) with nuclear factor kappa B (NF-κB) in hypomethylation of stemness genes.

Materials and Methods:
This experimental study was performed on HT-29 cells as human colorectal cancer cell lines. The interaction between TETs and DNA-methyltransferases 3 beta (DNMT3s) with p65 was achieved by coimmunoprecipitation. TETs were knocked down using siRNA, and the efficacy was analyzed by reverse-transcriptase polymerase chain reaction. The promoter methylation status of the target genes (NANOG, MYC) was determined by the methylation-sensitive high-resolution melting method.

Results:
TET3 and DNMT3b functionally interacted with p65 in samples through 25 ng/ml TNF-α treatment for 48 h in HT-29 cells. Transfection with siRNA significantly decreased the expression of TET enzymes after 72 h. Interestingly, treatment with TET siRNAs enhanced methylation of MYC and NANOG genes in samples with 25 ng/ml TNF-α treatment for 72 h in HT-29 cells. Moreover, methylation effects of TET3 were stronger than those of TET1 and TET2.

Conclusions:
These results suggest that inflammation may alter the methylation status of genes required for stemness and predispose the cells to neoplastic alterations.
Submucosal Infiltration versus Intravenous Administration of Dexamethasone in Decreasing Post-operative Inflammatory Sequelae after Third Molar Surgery - A Comparative Study
Authors: Naik Vinayak Gourish , Shankar M. N. Ravi , Agarwal Rashmi , Rai Kirthi Kumar , Karande Amol , Humne Abhijeet 
Published: November 2024

Abstract

Introduction:
Surgical removal of lower third molar is one of the most common surgical procedures and is quite stressful for many patients. In this study, two different routes of administration of dexamethasone 8 mg (intravenous [IV] vs. submucosally infiltrated) were used to evaluate the role of dexamethasone in reducing the post-operative inflammatory sequelae following lower third molar removal.

Materials and Methods:
Sixty patients who had to undergo surgical removal of mandibular third molars were randomly divided into two groups, each group consisting of 30 patients. One group of patients was administered 8 mg dexamethasone submucosally five min before the surgery. Another group of patients received 8 mg dexamethasone intravenously five min before the surgery. Facial swelling and pain were measured on the 2nd, 4th and 7th post-operative days.

Results:
The results of this study revealed that both the routes were effective in controlling post-operative pain and swelling. IV route of dexamethasone showed higher efficacy compared to submucosal (SM) route of dexamethasone in reducing the post-operative inflammatory sequelae in the surgical removal of impacted lower third molar teeth.

Discussion:
It was seen that IV dexamethasone (8 mg) and submucosal dexamethasone (8 mg) had equivalent ratings in terms of reduction of swelling and pain. Although the results of this study showed both the routes are effective in controlling post-operative swelling and pain after third molar surgery, the study concluded that certain benefits of submucosal route make the sm route to be a valuable alternative to iv dexamethasone.
A Rare Cause of Peripheral Vascular Disease: Monckeberg’s Medial Arteriosclerosis-Case Report
Authors: Anbarasan Kanmani , Elancheralathan K. , Kumar Ashok 
Published: November 2024

Abstract
Monckeberg’s disease, medial calcific arteriosclerosis, is a rare cause of severe lower-limb ischemia with an unclear etiology. We report the case of a 31-year-old male patient with recently diagnosed diabetes with left critical lower-limb ischemia, open revascularization done with improved ABI, and healing of an ulcer. After 3 months, the patient presented with rest pain and an ABI fall and finally ended up with a left below-knee amputation. Histopathological diagnosis showed that arteriosclerosis is associated with Monckeberg’s sclerosis.
Towing Away 18 mm Stent from the Right Atrium Using an Assembly of a Balloon and a Snare
Authors: Verma Himanshu , Sachan Trisha , Kumar Tanya 
Published: November 2024

Abstract
Superior vena cava (SVC) stenting is a common procedure utilized in managing SVC syndrome, whether it is due to a malignancy or secondary to benign causes such as indwelling catheters. The potential for unanticipated stent dislodgment exists, as illustrated in the presented case where the stent dislodged into the right atrium, posing a threat of cardiac tamponade. In such critical scenarios, the ideal approach involves endovascular retrieval, effectively minimizing patient morbidity. In this report, our objective was to outline a practical approach to retrieving an 18 mm diameter dislodged stent using a combination of a snare and balloon.
A Rare Complication of Internal Jugular Venous Cannulation for Hemodialysis – Carotid-Jugular Fistula
Authors: Jha Aandrei Jivendra , Kumar Tushar 
Published: November 2024

Abstract
Cannulation of the internal jugular vein for hemodialysis (HD) is a common procedure due to easy access and placement. Inadvertent puncture of the common carotid artery is a rare complication (<1%), and consequential Carotid-Jugular Fistula (CJF) is even rare, with only a handful of cases reported in the literature. This complication can develop insidiously and can be easily missed initially. We describe a patient with iatrogenic chronic left CJF secondary to an HD catheter inserted over 6 months ago at the same site. The patient was successfully diagnosed and treated with surgical ligation and remains asymptomatic till date.
Validation, Adaptation and Assessment of Orofacial Esthetic Scale in Hindi Language
Authors: Paulina  , Dhawan Pankaj , Jain Neha , Khan Uswah 
Published: November 2024

Abstract

Context:
The Hindi version of the Orofacial Esthetic Scale (OES) captures esthetic preferences and concerns specific to Hindi-speaking populations, making it more accessible to a wider audience. It also facilitates clear communication between healthcare professionals and patients, enhancing understanding and interactions. It facilitates cross-cultural research and helps improve healthcare equity by ensuring quality healthcare services tailored to the needs of the population.

Aims:
The aim of the study was to adapt and assess the Hindi version of the Orofacial Esthetic Scale-Hindi version (OES-H), validated for subjects needing or not needing prosthodontic treatment.

Settings and Design:
The study was conducted in the prosthodontic department of the institution. Patient recruitment was carried out consecutively until the required test population size of 162 patients was achieved. Patients were categorized into three groups based on their treatment requirements: No treatment (NT) requiring group, prosthodontic treatment (PT) requiring group, and esthetic prosthodontic treatment (EPT) requiring group. Patient recruitment for the NT group occurred during routine hygiene check-ups, while recruitment for the PT and EPT groups took place at the commencement of PT.

Methods and Materials:
The OES-H was obtained through a cross-culture adaptation process. The psychometric properties of the obtained version were then observed in a group of 54 prosthodontic and 54 non-prosthodontic patients and 54 patients requiring EPT.

Statistical Analysis Used:
Discriminant and convergent validity and reliability were measured.

Results:
The OES-H scores were found to be significantly higher for subjects not requiring EPT.

Conclusions:
The OES-H can be used as an effective tool for measuring the self-perceived aesthetic appearance in dental practice and research.
Two cases of hyperphosphatemic familial tumoral calcinosis with varied etiology and unique presentations
Authors: Thomas Glady , Kunnuru Sumana Reddy , Anne Beatrice , Divyasri Namburi , Ranganath Prajnya , Uppin Megha 
Published: November 2024

ABSTRACT
Hyperphosphatemic familial tumoral calcinosis is a rare disorder caused by fibroblast growth factor 23 (FGF23) deficiency or resistance resulting in elevated serum phosphorus levels in blood. Predominant clinical manifestations observed are ectopic calcification, hyperostosis, and rarely chronic recurrent multifocal osteomyelitis. It exhibits autosomal recessive inheritance and is associated with variants in three genes: FGF23, GALNT3, and KLOTHO. Recently, an acquired autoimmune variant has also been reported. In this report, we present two cases. One case presented with a clinical picture of chronic recurrent osteomyelitis and was found to have a variant in the GALNT3 gene. The other case exhibited typical manifestations but did not have an identifiable variant, and hence we are presuming it to be an acquired autoimmune variant.
Fibrin-glue-assisted retinopexy for coloboma-associated retinal detachment
Authors: Jain K Shreeya , Upadhyaya Abhishek , Raval Vishal R 
Published: November 2024

Background:
Retinal detachment (RD) is common (23%–40%) in eyes with uveal coloboma due to early vitreous syneresis, inherent defects at the locus minoris resistentiae, and breaks in intercalary membrane (ICM).[1] Managing eyes with coloboma RD is difficult due to complexity of accessing and repairing retinal breaks. In RD surgeries, tamponade agents are used to provide surface tension across retinal breaks to prevent further fluid flow into the subretinal space until the effect of retinopexy is permanent. According to Tyagi et al., fibrin glue-assisted retinopexy for rhegmatogenous retinal detachment after pars plana vitrectomy is a promising technique that allows early visual recovery and obviates the need for postoperative positioning.[2] Fibrin glue, being an inert substance, usually stays for 1–2 weeks, making it an ideal temporary tamponade to plug the retinal break until the retinopexy effect becomes permanent.

Purpose:
To assess the role of fibrin-glue-assisted retinopexy in coloboma-associated RD.

Synopsis:
A male child presented with sudden diminution of vision in the left eye 5 days after trauma. His visual acuity was limited to counting fingers close to face. On examination, a type 3 coloboma with total rhegmatogenous RD and detached ICM was observed. A standard three-port 23G vitrectomy was performed, followed by a core vitrectomy. Triamcinolone-assisted posterior vitreous detachment was initiated, followed by the completion of peripheral vitrectomy. As no obvious retinal breaks were noted, subretinal injection of brilliant blue dye was used to locate the break within the coloboma using the dye extrusion technique. After fluid–air exchange, the dye was observed extruding into the vitreous cavity, thereby confirming the break within the coloboma. Laser retinopexy was done around edges of the coloboma in a continuous mode. Fibrin glue was injected over the site of the break and left for 1 min until a thick coagulum was formed, thereby plugging the retinal break. During the postoperative period, positioning was not advised. On day 5, best corrected visual acuity (BCVA) improved to 20/320 with an attached retina. At the last follow-up, the retina remained attached, and BCVA was 20/50.

Highlights:
In this interesting case, we illustrate a unique method of plugging the retinal break for coloboma-associated RD using fibrin glue, thereby obviating the need for long-term tamponade and positioning, especially in pediatric patients.

Video link:

https://youtu.be/M4yu_6aZ_R0