bluuebunny/crossref_metadata_2025_split huggingface dataset:
A mobile brain-body imaging dataset recorded during treadmill walking with a brain-computer interface
Authors: He Yongtian , Luu Trieu Phat , Nathan Kevin , Nakagome Sho , Contreras-Vidal Jose L. 
Published: April 2018

AbstractWe present a mobile brain-body imaging (MoBI) dataset acquired during treadmill walking in a brain-computer interface (BCI) task. The data were collected from eight healthy subjects, each having three identical trials. Each trial consisted of three conditions: standing, treadmill walking, and treadmill walking with a closed-loop BCI. During the BCI condition, subjects used their brain activity to control a virtual avatar on a screen to walk in real-time. Robust procedures were designed to record lower limb joint angles (bilateral hip, knee, and ankle) using goniometers synchronized with 60-channel scalp electroencephalography (EEG). Additionally, electrooculogram (EOG), EEG electrodes impedance, and digitized EEG channel locations were acquired to aid artifact removal and EEG dipole-source localization. This dataset is unique in that it is the first published MoBI dataset recorded during walking. It is useful in addressing several important open research questions, such as how EEG is coupled with gait cycle during closed-loop BCI, how BCI influences neural activity during walking, and how a BCI decoder may be optimized.
Wide-field corneal subbasal nerve plexus mosaics in age-controlled healthy and type 2 diabetes populations
Authors: Lagali Neil S. , Allgeier Stephan , Guimarães Pedro , Badian Reza A. , Ruggeri Alfredo , Köhler Bernd , Utheim Tor Paaske , Peebo Beatrice , Peterson Magnus , Dahlin Lars B. , Rolandsson Olov 
Published: April 2018

AbstractA dense nerve plexus in the clear outer window of the eye, the cornea, can be imaged in vivo to enable non-invasive monitoring of peripheral nerve degeneration in diabetes. However, a limited field of view of corneal nerves, operator-dependent image quality, and subjective image sampling methods have led to difficulty in establishing robust diagnostic measures relating to the progression of diabetes and its complications. Here, we use machine-based algorithms to provide wide-area mosaics of the cornea’s subbasal nerve plexus (SBP) also accounting for depth (axial) fluctuation of the plexus. Degradation of the SBP with age has been mitigated as a confounding factor by providing a dataset comprising healthy and type 2 diabetes subjects of the same age. To maximize reuse, the dataset includes bilateral eye data, associated clinical parameters, and machine-generated SBP nerve density values obtained through automatic segmentation and nerve tracing algorithms. The dataset can be used to examine nerve degradation patterns to develop tools to non-invasively monitor diabetes progression while avoiding narrow-field imaging and image selection biases.
109 years of forest growth measurements from individual Norway spruce trees
Authors: Kindermann Georg E. , Kristöfel Ferdinand , Neumann Markus , Rössler Günter , Ledermann Thomas , Schueler Silvio 
Published: April 2018

AbstractIn 1892 a forest spacing experiment with four different spacing patterns was established with Norway spruce (Picea abies). From 1923 until 1997, when the stand was harvested, diameter, height and height to crown base of in total 4507 trees were measured up to 23 times. The original aim of the experiment during establishment was to analyse short term effects of different spacing patterns. The thinning regime followed state of the art forestry practises. During the observation time of more than 100 years, the individual observers and the measurement technology changed several times. Thus, the raw measurement data contain systematic and unsystematic measurement errors as well as missing data. We developed methods to complete missing data, smoothen implausible developments, and correct measurement errors. The data provided in the present study include spatially explicit individual-tree growth data which can be used to analyse the development of forest stands and its individual trees during one rotation period. The data can be used e.g. to parameterize and validate forest growth and competition models.
Efficiency optimisation of ZVS isolated bidirectional DAB converters
Authors: Dung Nguyen Anh , Chiu Huang‐Jen , Lin Jing‐Yuan , Hsieh Yao‐Ching , Liu Yu‐Chen 
Published: April 2018

This study presents a control method for isolated bidirectional dual‐active‐bridge converters to optimise the efficiency by achieving the zero‐voltage switching (ZVS) in high‐voltage applications, which the switching losses are the major issues. At light‐load condition, the duty control algorithm is proposed to achieve the ZVS for all switches while the triple phase shift with ZVS condition is realised at heavy load condition. The operating principles and the design considerations of the proposed control scheme are analysed in detail. A 2 kW prototype converter is built up and tested to verify the feasibility of the proposed control strategy.
Non‐enzymatic continuous glucose monitoring system
Authors: Moore Sean , You Byoung Hee , Kim Namwon , Park Taehyun , Song In‐Hyouk 
Published: April 2018

A prominent field of study in biosensor development is the study of electric properties which provide valuable insight into the fluids contents. In this research, a non‐enzymatic glucose sensor is fabricated, characterised, and employed. The developed device determines the effects of electrode surface area on sensing efficacy, the effects of glucose concentration on impedimetric response, and a real‐time measurement of glucose concentration. Deviations throughout the entire glucose range are detected as an inverse of the impedance in the cell due to the inverse relationship of glucose concentration and charge transfer resistance. The continuous monitoring of glucose is demonstrated by a rapid device response over two iterations of glucose concentration in ascending order: 50 µM, 400 µM, and 3.2 mM. At a sustained frequency of 10 kHz, the result shows a stable impedimetric response of 1038, 752, and 688 kΩ, respectively. The validity of the device as a continuous glucose monitoring method is carried out by repeating the cycle and observing the response.
Accurate rest frequencies for propargylamine in the ground and low-lying vibrational states
Authors: Degli Esposti C. , Dore L. , Puzzarini C. , Biczysko M. , Bloino J. , Bizzocchi L. , Lattanzi V. , Grabow J.-U. 
Published: April 2018

Context.To date, several complex organic molecules have been detected in the interstellar medium, and they have been suggested as precursors of biologically important species. Propargylamine (HC ≡C−CH2−NH2) is structurally similar to a number of other organic molecules which have already been identified by radioastronomy, making it a good candidate for astrophysical detection.Aims.This work provides accurate rest frequencies of propargylamine, from the centimeter-wave to the submillimeter-wave region, useful to facilitate the detection of this molecule in the interstellar medium.Methods.An extensive laboratory study of the rotational spectrum of propargylamine has been performed using a pulsed-jet Fourier Transform Microwave (FTMW) spectrometer (7–19 GHz frequency range) and a frequency modulation microwave spectrometer (75–560 GHz). Several hundred rotational transitions of propargylamine were recorded in the ground and three lowest excited vibrational states. The experiments were supported by high-level ab initio computations, mainly employed to characterize the vibrational state structure and to predict spectroscopic parameters unknown prior to this study.Results.The measured transition frequencies yielded accurate rotational constants and the complete sets of quartic and sextic centrifugal distortion constants for propargylamine in its vibrational ground state.14N-nuclear quadrupole coupling constants were also determined. Rotational and quartic centrifugal distortion constants were also obtained for the low-lying excited statesv13= 1 (A′),v20= 1 (A″), andv21= 1 (A″). Thea-type Coriolis resonance which couples thev13= 1 andv21= 1 levels was analyzed.Conclusions.The determined spectroscopic constants allowed for the compilation of a dataset of highly accurate rest frequencies for astrophysical purposes in the millimeter and submillimeter regions with 1σuncertainties that are smaller than 0.050 MHz, corresponding to 0.03 km s−1at 500 GHz in radial equivalent velocity.
Gaia Data Release 2
Authors: Sartoretti P. , Katz D. , Cropper M. , Panuzzo P. , Seabroke G. M. , Viala Y. , Benson K. , Blomme R. , Jasniewicz G. , Jean-Antoine A. , Huckle H. , Smith M. , Baker S. , Crifo F. , Damerdji Y. , David M. , Dolding C. , Frémat Y. , Gosset E. , Guerrier A. , Guy L. P. , Haigron R. , Janßen K. , Marchal O. , Plum G. , Soubiran C. , Thévenin F. , Ajaj M. , Allende Prieto C. , Babusiaux C. , Boudreault S. , Chemin L. , Delle Luche C. , Fabre C. , Gueguen A. , Hambly N. C. , Lasne Y. , Meynadier F. , Pailler F. , Panem C. , Riclet F. , Royer F. , Tauran G. , Zurbach C. , Zwitter T. , Arenou F. , Gomez A. , Lemaitre V. , Leclerc N. , Morel T. , Munari U. , Turon C. , Žerjal M. 
Published: April 2018

Context. The Gaia Data Release 2 (DR2) contains the first release of radial velocities complementing the kinematic data of a sample of about 7 million relatively bright, late-type stars.
Aims. This paper provides a detailed description of the Gaia spectroscopic data processing pipeline, and of the approach adopted to derive the radial velocities presented in DR2.
Methods. The pipeline must perform four main tasks: (i) clean and reduce the spectra observed with the Radial Velocity Spectrometer (RVS); (ii) calibrate the RVS instrument, including wavelength, straylight, line-spread function, bias non-uniformity, and photometric zeropoint; (iii) extract the radial velocities; and (iv) verify the accuracy and precision of the results. The radial velocity of a star is obtained through a fit of the RVS spectrum relative to an appropriate synthetic template spectrum. An additional task of the spectroscopic pipeline was to provide first-order estimates of the stellar atmospheric parameters required to select such template spectra. We describe the pipeline features and present the detailed calibration algorithms and software solutions we used to produce the radial velocities published in DR2.
Results. The spectroscopic processing pipeline produced median radial velocities for Gaia stars with narrow-band near-IR magnitude GRVS ≤ 12 (i.e. brighter than V ~ 13). Stars identified as double-lined spectroscopic binaries were removed from the pipeline, while variable stars, single-lined, and non-detected double-lined spectroscopic binaries were treated as single stars. The scatter in radial velocity among different observations of a same star, also published in Gaia DR2, provides information about radial velocity variability. For the hottest (Teff ≥ 7000 K) and coolest (Teff ≤ 3500 K) stars, the accuracy and precision of the stellar parameter estimates are not sufficient to allow selection of appropriate templates. The radial velocities obtained for these stars were removed from DR2. The pipeline also provides a first-order estimate of the performance obtained. The overall accuracy of radial velocity measurements is around ~200–300 m s−1, and the overall precision is ~1 km s−1; it reaches ~200 m s−1 for the brightest stars.
Bedside Ultrasound-Guided Percutaneous Needle Aspiration of Intra- and Extra-Axial Intracranial Hemorrhage in Neonates
Authors: Cizmeci Mehmet , Thewissen Liesbeth , Zecic Alexandra , Woerdeman Peter , Boer Bart , Baert Edward , Govaert Paul , Dudink Jeroen , Groenendaal Floris , Lequin Maarten , de Vries Linda 
Published: April 2018

AbstractIntracranial hemorrhage is an important cause of brain injury in the neonatal population and bedside percutaneous needle aspiration has emerged as an alternative due to the major risks that can be caused by standard neurosurgical decompression. We aimed to assess the effectiveness of this minimally invasive bedside technique and conducted a retrospective analysis of all newborn infants with a large extra-axial hemorrhage associated with a parenchymal hemorrhage causing a midline shift, managed at three academic centers over a 15-year period. Collected data included clinical history, laboratory results, review of all imaging studies performed, and neurodevelopmental follow-up. Eight infants (3 preterm and 5 full-term) presented on day 1 to 2 with seizures (n = 6) and apneas (n = 5), signs of increased intracranial pressure (n = 4), and coning (n = 1). Risk factors were present in six. Cranial ultrasound and computed tomography showed a midline shift in all; two infants showed status epilepticus on amplitude-integrated electroencephalography with complete resolution after the procedure. Between 7 and 34 mL could be aspirated associated with a decrease in the midline shift as seen by ultrasonography performed during the puncture. No complications were seen related to the procedure and none of the infants required further acute neurosurgical intervention. On follow-up, three had mild sequelae, including motor coordination problems (n = 1) and hemianopia (n = 2); none developed cerebral palsy or postneonatal epilepsy. Neonates, presenting with severe symptoms, can be managed successfully using ultrasound-guided needle aspiration and this minimally invasive bedside method should be kept in mind before performing neurosurgical decompression.
Reevaluation of Protein Intake for Preterm Infants
Authors: Kawai Masahiko 
Published: April 2018

AbstractGrowth failure caused by undernutrition is considered one of the major causes for psychomotor delay in extremely preterm infants, and the concept for “aggressive nutritional approach” is widely accepted worldwide. Based on this, postnatal early catch-up growth due to sufficient supply of nutrients including sufficient amounts of amino acids is believed to be essential for a better outcome; however, there is no definitive evidence of aggressive nutrition on better outcomes in mortality, growth, and neurodevelopment. On the contrary, epidemiological evidence suggests that low birth weight and a rapid catch-up growth after birth are major risk factors for insulin resistance and diabetes in later life; higher protein intake during postnatal period relates to higher cardiovascular risk in later life. Considering these, optimal nutrition, especially protein administration, should be reevaluated. In this review, current opinions on the nutrition for the preterm infants are surveyed. In addition, I propose a new concept for optimized protein amount for the preterm infants based on the difference of amino acid metabolism between fetuses and preterm infants.
Update on the Role of Stem Cells in the Treatment of Hirschsprung Disease
Authors: Lui Kathy , Tam Paul , Ngan Elly 
Published: April 2018

AbstractStem cells possess the ability of self-renewal and the potency to differentiate into multiple cell lineages. Somatic stem cells are present in adult tissues, but they usually exhibit limited differentiation capacity and life span. On the other hand, somatic cells from adult tissues can be reprogrammed into induced pluripotent stem cells (iPSCs) that retain a full differentiation capacity with unlimited self-renewal ability. Autologous origin of iPSCs makes them an ideal source of cells for regenerative medicine to replenish the missing or damaged cells in the patients. iPSCs nowadays have also been widely used to build human disease models to study pathological mechanisms of the diseases. Hirschsprung disease (HSCR) is a congenital disorder caused by defects in the development of enteric neural crest stem cells. The failures of the ENCCs to proliferate, differentiate, and/or migrate lead to the absence of enteric neurons in the distal colon, resulting in colonic motility dysfunction. The lack of effective treatment for HSCR urges continuous efforts to develop new therapies for this congenital disorder. In this review, we will discuss the potential applications of somatic stem cells and iPSCs for the cell-based therapy of HSCR. We will also highlight the recent advances in stem cell research for the establishment of human HSCR models for the development of novel therapies.
The construction of new scientific norms for solving Grand Challenges
Authors: Maxwell Kate , Benneworth Paul 
Published: April 2018

AbstractThere is an increasing recognition that there is a class of problems that society must solve urgently in the twenty-first century if humanity is to survive into the twenty-second century—the so-called ‘Grand Challenges’. Science policymakers have been active in recognising these challenges and the attendant need to develop new multidisciplinary ways of working. But embracing multidisciplinarity is not a straightforward choice for scientists, who individually are strongly steered by norms and values inculcated through their past scientific experiences. In this paper, therefore, we ask whether new funding approaches can contribute to creating new ways of working by scientists towards challenge-driven research, specifically by changing scientists’ expectations and beliefs. We address this research question with reference to a single new experimental method, the ‘research sandpit’, implemented experimentally in a single national science system, Norway. Our data are derived from interviews with scientists involved in the five research projects funded as a result of the first sandpit, called ‘Idélab’ (idea lab) and held in 2014, and with the Research Council of Norway. We conclude that the sandpit approach appeared to shift research perceptions of individual scientists, particularly around long-term belief structures. This implies that, when well managed, the sandpit model can indeed be useful to generate multidisciplinary research as part of a multifaceted approach to funding scientific research.
Cognitive and geographic constraints on morphosyntactic variation
Authors: Claes Jeroen 
Published: April 2018

AbstractIn this paper, I examine whether the variation patterns ofhaberpluralization (e.g.,hubo/hubieron fiestas‘there was/were parties’) in Peninsular Spanish corroborate the hypothesis elaborated in earlier work that the phenomenon constitutes a competition between two variants of the presentational construction withhaberthat is constrained by domain-general cognitive constraints on spreading activation. In addition, this paper examines whetherhaberpluralization is incrementing in frequency in particular Peninsular regions and whether or not the phenomenon is spreading geographically. To meet these objectives, I analyze a dataset of more than 7,500 cases ofhaber + plural NP, which were culled from two publicly available data sources: theCorpus Oral y Sonoro del Español Rural(which represents only rural speakers born before the 1940s;Fernández-Ordóñez 2005-) andTwitter(which represents mainly young and middle-aged speakers). The results of a mixed-effects logistic regression analysis that tests the effects of tense, the absence/presence of negation, typical action-chain position of the noun, the regional origin of the examples, and the data sources support the competition hypothesis. This model also supports that pluralizedhaberis spreading westward from its epicenters (Valencia, Barcelona, and Murcia), while also incrementing in frequency in northern, eastern and southern Spain. However, its frequency appears to be declining in central Spain. A geographically more detailed, but similar picture is obtained with three generalized additive mixed models that test the effects of geography on the total dataset as well as on each of the two subcorpora.
Expanding the causative alternation
Authors: Mangialavori Rasia Eugenia 
Published: April 2018

AbstractThe causative-inchoative alternation has been a subject of much debate. It might also be a case where variation patterns that escape existing typological descriptions provide a new perspective on the problem. We analyze the variability and systematicity of alternative argument structure realizations, together with corresponding aspectual/event properties, by considering three different ways in which change-of-state verbs can be semantically and syntactically construed in Romance. Under the general assumption that the syntactic projection of arguments correlates non-trivially with event structure, we apply a novel theoretical approach to the semantics and syntax of the causative-inchoative alternation. We argue that different verbal heads can be independently combined to yield contrasting verbal configurations, with corresponding event/argument structure properties quite freely. Alongside standard cases such as causative and inchoative frames, we discuss what we call ‘stative-causative constructions’ [SCC], where the initiator appears as the sole argument. The general properties of this additional (third) variant suggest the availability of a null causative (external-argument-selecting) v0producing original monoargumental structures with corresponding (simpler) event structure. These little-known Spanish data challenge current argument structure theories assuming that the causative v0necessarily implicates the eventive (BECOME) component, or that the latter figures in the verb’s permanent lexical entry. SCCs provide empirical evidence suggesting that what is commonly described as a basic unaccusative/transitive verb may have unergative uses.
Exploring the Left Dislocation construction by means of multiple linear regression
Authors: Tizón-Couto David 
Published: April 2018

AbstractThis study deals with the complexity of left-dislocated [LDed] noun phrases in the Modern English period (1500–1914). The purpose is twofold: to estimate the effects of a number of theoretically relevant predictors on complexity, operationalized as word-length, and to explore whether shorter LDed NPs, which are characteristic of contemporary spoken English, symbolize the claimed ‘orality’ of earlier speech-related texts. Multiple linear regression is employed in order to assess the correlation between complexity and factors relating to both the context (e.g. genre) and the inner configuration (e.g. augmentation of the LDed constituent) of the tokens extracted from the Penn-Helsinki suite of corpora. The results confirm that shorter LDed items more closely match the characterization previously offered for contemporary spoken Left Dislocation. The results also provide preliminary insight into the accommodation strategies that might facilitate the resumption of heavier LDed NPs. As regards genre, speech-purposed and mixed texts feature a higher relative rate of shorter LDed elements. Thus, if shorter LDed NPs are more closely connected with the spoken variant, it is in speech-purposed and mixed genres where they might be claimed to constitute a trait of orality that is deliberately employed by writers in order to reproduce conversation. Surprisingly, speech-like genres do not include LDed items as often, and these are just as complex as those attested in writing-related texts.