bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative and postoperative complications of partial maxillectomy for the treatment of oral tumors in dogs
Authors: MacLellan Roxane H. , Rawlinson Jennifer E. , Rao Sangeeta , Worley Deanna R. 
Published: June 2018

Abstract
OBJECTIVE To characterize and identify factors associated with intraoperative and postoperative complications of maxillectomy in dogs with oral tumors.
DESIGN Retrospective cohort study.
ANIMALS 193 dogs that underwent maxillectomy for oral tumor excision from 2000 through 2011.
PROCEDURES Data were extracted from the medical records regarding dog signalment, tumor location and size, histologic findings, clinical stage, maxillectomy category, surgical approach, and additional treatments provided. These factors were examined for associations with recorded intraoperative and postoperative outcomes.
RESULTS The most common intraoperative complication was excessive surgical bleeding (103/193 [53.4%]), for which 44 (42.7%) dogs received an intraoperative blood transfusion. These outcomes were both significantly associated with tumor size and location, maxillectomy type, and surgical approach. Dogs treated with a dorsolateral combined intraoral surgical approach were more likely to have excessive surgical bleeding (48/58 [83%]) and had a longer mean duration of surgery (106 minutes) than those treated with an intraoral approach (29/54 [54%] and 77 minutes, respectively). Complications developing within 48 hours after surgery included epistaxis (99/193 [51.3%]), excessive facial swelling (71/193 [36.8%]), facial pawing (21/193 [10.9%]), and difficulty eating (22/193 [11.4%]). Complications developing within 48 hours to 4 weeks after surgery included lip trauma (22/164 [13.4%]), oronasal fistula formation (18/164 [11.0%]), wound dehiscence (18/164 [11.0%]), and infection (13/164 [7.9%]).
CONCLUSIONS AND CLINICAL RELEVANCE Complications associated with maxillectomy in dogs were generally minor. Aggressive surgical planning, preparedness for hemorrhage and transfusion, careful tissue dissection, and comprehensive pain control are recommended, particularly for dogs with large, caudally located oral tumors requiring extensive excision.
Laparoscopic ovariectomy with a single-port multiple-access device in seven African lionesses (Panthera leo)
Authors: Leclerc Antoine , Decambron Adeline , Commère Cédric , Mulot Baptiste , Viateau Véronique , Manassero Mathieu 
Published: June 2018

Abstract
CASE DESCRIPTION 7 privately owned female African lions (Panthera leo) that had been bred for public exhibition and were housed in outdoor pens were evaluated prior to undergoing elective ovariectomy.
CLINICAL FINDINGS All animals were healthy. Median age was 15 months (range, 9 to 34 months), and median body weight was 71 kg (156 lb; range, 48 to 145 kg [106 to 319 lb]).
TREATMENT AND OUTCOME Surgical sterilization by means of single-incision laparoscopic ovariectomy was elected. A 2- to 3-cm-long skin incision was made just caudal to the umbilicus, and a single-port multiple-access device was bluntly inserted through the incision. Traction was maintained with stay sutures to provide counterpressure, and three 5-mm-diameter cannulae were introduced through the device's access channels with a blunt trocar. The abdomen was insufflated to a pressure of 12 mm Hg with CO2. Each ovary was grasped and suspended with a standard 36-cm-long laparoscopic grasper, and ovariectomy was performed with a 5-mm vessel sealer and divider device. Because of the depth of subcutaneous fat, extensive subcutaneous dissection was necessary to insert the single-port device. In contrast, fat content of the mesovarium was minimal and did not vary markedly among animals. Subjectively, single-incision laparoscopic ovariectomy was easily performed, but all surgeons had experience in laparoscopic surgery. Median duration of the surgical procedure was 29 minutes (range, 21 to 49 minutes). No perioperative complications were encountered.
CLINICAL RELEVANCE Findings suggested that the single-incision laparoscopic technique may be an acceptable, minimally invasive option for ovariectomy of large felids.
Trabalhos de Conclusão de Curso (TCC): 26ª e 27ª, 28ª Turmas de Formandos: Resumos.
Authors: Avelar Maria do Carmo Querido , Car Marcia Regina , Cardoso Luciana Gonzaga dos Santos , Suzzio Fábio Pinto , Noca Cell Regina Da Silva , Prete Kryssia Marton , Silva Magda Aparecida Dos Santos , Silva Benta Alves da , Reppetto Maria Angela , Gracio Stephanie Peixoto , Souza Graziela Ramos Barbosa de , Silva José Cícero da , Passos Vanda Cristina Dos Santos , Andrade Giovana A.S. Cogo Rodrigues , Terra Maria Fernanda , Almeida Carlos Alberto de , Costa Maria Lucia Alves de Sousa 
Published: June 2018

APRESENTAÇÃO Este 14º volume de resumos, o 4º publicado como Suplemento da Revista Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo, dos Trabalhos de Conclusão do Curso (TCC) de Graduação em Enfermagem das 26ª, 27ª e 28ª turmas de alunos, foi organizado em duas grandes linhas de pesquisa. A primeira linha, Cuidar em Enfermagem, inclui estudos sobre diferentes aspectos da assistência de enfermagem nas áreas da Saúde do Adulto e do Idoso, Saúde da Mulher e Saúde da Criança e do Adolescente, inseridos nos níveis de atenção: primária, secundária e terciária. A segunda linha de pesquisa, Trabalho e Educação em Enfermagem, inclui dentre outros, estudos sobre conhecimentos, atitudes, qualidade de vida, acidentes e condições de trabalho dos enfermeiros, alunos e profissionais de saúde.As Organizadoras
KAJIAN BANDINGAN DESAIN VISUAL SITUS PRODUK FURNITUR IKEA DAN OLYMPIC PERIODE 2015
Authors: YONATIA JESSICA 
Published: June 2018

Nowadays as technology grows and globalization affects, most companies usually have product catalogues on website as an advertising and online shopping as well. The study attempts to identify visual appearance comparison of Ikea and Olympic websites, by aesthetic elements which suit to visual communication design's principles. The applied method is qualitative method supported by theories and field survey. The result will be outlined as descriptive analysis which may be a reference in making an effective, informative and visually aesthetic commercial website. Keywords: aesthetic; commercial website; online; visual communication design
STUDI PERILAKU ADAPTASI MANUSIA TERHADAP LINGKUNGAN SOSIAL DALAM PENAMBAHAN FUNGSI RUANG KOMERSIAL HUNIAN TRADISIONAL BALI DI UBUD
Authors: HALIM ERWIN ARDIANTO 
Published: June 2018

Tourism in Bali has significant effect to Balinese social aspect. It can be seen from the Balinese people daily behavior that has changed from traditional society to modern and diverse society. The conviction to conserve traditional pattern of life and behavior is still exists in the Balinese society and their posterity, but in the other side, tourism development and economical urgency creates difficult situation to conserve the purity of Balinese cultural tradition. This situations influence Balinese cultural products created nowadays, such as architectural spaces that represent the people within. The changes occurring in traditional Balinese houses happened mostly in concentrated tourism areas, such as Ubud. In the government urban development plan, Ubud is selected as one of strategic tourism point of interest that is cultural tourism. Consequently, Ubud also functions as strategic economic income resource for Bali. The changes in traditional Balinese houses mostly happened because of the need to adapt with socio-cultural context, where local tourists and expatriates come and even stay for longer time. To accommodate tourist’s needs, Ubud villagers set off to open restaurants, cafes, art galleries, souvenir shops, and travel agents in their houses. These commercial areas are located in their traditional houses, with modification of rooms or even addition of rooms with other functions. This research focused on the space transformation to commercial spaces in traditional Balinese houses. There are abundant philosophical values that have to be conserve in traditional Balinese houses between generations. Those philosophical values have sacred meanings within its design elements, such as building orientation, building elevation, facades, borders and zoning. With the addition of commercial places, how do The Ubud people managed to continue their tradition and the values within? Therefore, the main problem that is being researched here is about the collision between the need to adapt to socio-cultural context in the society and the need to conserved cultural traditions in the family and their sacred meanings. Keywords: human adaptative behaviour; space transformation; traditional house; Ubud
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE TEAMS GAMES TOURNAMENT (TGT) TERHADAP HASIL BELAJAR IPA SISWA KELAS VIII SMP DITINJAU DARI KERJASAMA SISWA
Authors: Ismah Zahrina , Ernawati Tias 
Published: June 2018

Penelitian bertujuan untuk mengetahui pengaruh penggunaan model pembelajaran kooperatif tipe Teams Games Tournament (TGT) terhadap hasil belajar IPA siswa kelas VIII SMP N 3 Kasihan ditinjau dari kerjasama siswa. Objek penelitian ini adalah hasil belajar IPA siswa. Penelitian ini adalah quasi eksperiment. ÃÂ Teknik pengumpulan data menggunakan teknik tes, teknik angket, dan teknik dokumentasi. Instrument tes berupa soal pilihan ganda yang berjumlah 30 soal dan instrumen angket berupa pernyataan yang berjumlah 20 butir. Hasil perhitungan diperoleh Fhitung = 9,315 dengan p = 0,004 dan rerata hasil belajar sebesar 20,192, rerata hasil angket sebesar 77,846. Uji hipotesis menunjukkan ada perbedaan hasil belajar siswa yang pembelajarannya menggunakan model TGT dan ekspositori. Berdasarkan rerata hasil belajar dan hasil angket, maka dapat ditarik kesimpulan bahwa ada pengaruh penggunaan model pembelajaran kooperatif tipe TGT terhadap hasil belajar IPA siswa kelas VIII di tinjau dari kerjasama siswa.ÃÂ
The Problems of The Families Who Have Autistic Children: A Qualitative Research
Authors: Nuri Cahit , Rüştioğlu Omaç , Pişkin Abidoğlu Ülkü 
Published: June 2018

Autism is defined as one of
the neurodevelopmental disabilities which continue for life and affect social
development, communication and behaviors of the individuals in a negative
sense. Purpose of this study is to determine
how parents with autistic children figure out the autism, what their reactions
are and what the effect of the believe is to accept it, how they declare it to
the people around them and how the reaction of people is, who and how they get
support from and what the possible future difficulties and requirements are.
The study was based on qualitative research method and interview form prepared
based on the purpose by the researcher was used in the study. The study is
based on case study which is a qualitative research method and uses an
interview form that is prepared by the researcher according to the purpose of
the study. Study group is composed of 15 mothers and 8 fathers selected by
purposive sampling method among parents of children going to special education
centers. Study results have been shown that, it was found that the parents first
noticed the inadequacy of language development without noticing the autism. In addition, it was seen that the first
reaction of the parents' children to get autism was also the intense sadness.
There is another result which is that parents need to get information about an
autism with the sadness they have experienced.
Parents have expressed concern about the future of their children,
depending on the strength of their children's self-expression. It has been
determined that the society has negative attitudes towards autistic children
and that parents would like to see the society to be more moderate towards
autistic children. Results have been determined, it is important to establish
empirical studies that will increase the awareness of other individuals about
autism while showing the needs for supporting from autistic families. Study findings have been
discussed with similar study findings included in the literature.
Preparation of micro/nanopatterned gelatins crosslinked with genipin for biocompatible dental implants
Authors: Makita Reika , Akasaka Tsukasa , Tamagawa Seiichi , Yoshida Yasuhiro , Miyata Saori , Miyaji Hirofumi , Sugaya Tsutomu 
Published: June 2018

Background: Collagen is a basic component of the periodontium and plays an important role in the function of the periodontal unit. Therefore, coating with collagen/gelatin has been applied to enable dental implants to positively interact with peri-implant tissues. Although the micro/nanoscale topography is an important property of the surface of dental implants, smaller collagen/gelatin surface patterns have not been sufficiently developed. Furthermore, only few reports on the behavior of cells on gelatin surfaces with different patterns and sizes exist. In this study, we developed micro/nanometer-scaled gelatin surfaces using genipin crosslinking, with the aim of understanding the use of patterning in surface modification of dental implants.Results: Grooves, holes, and pillars, with widths or diameters of 2 µm, 1 µm, or 500 nm were fabricated using a combination of molding and genipin crosslinking of gelatin. The stability of the different gelatin patterns could be controlled by the degree of genipin crosslinking. The gelatin patterns at 20 mM concentration of genipin and 41% crosslinking maintained a stable, patterned shape for at least 14 days in a cell culture medium. A cell morphology study showed that the cells on groves were aligned along the direction of the grooves. In contrast, the cells on pillars and holes exhibited randomly elongated filopodia. The vinculin spots of the cells were observed on the top of ridges and pillars or the upper surface of holes. The results of a cell attachment assay showed that the number of surface-attached cells increased with increasing patterning of the gelatin surface. Unlike the cell attachment assay, the results of a cell proliferation assay showed that Saos-2 cells prefer grooves with diameters of approximately 2 µm and 1 µm and pillars with diameters of 1 µm and heights of 500 nm. The number of cells on pillars with heights of 2 µm was larger than those of the other gelatin surface patterns tested.Conclusion: These data support that a detailed design of the gelatin surface pattern can control both cell attachment and proliferation of Saos-2 cells. Thus, gelatin surfaces patterned using genipin crosslinking are now an available option for biocompatible material patterning.
A Photometric, Spectroscopic, and Apsidal Motion Analysis of the F-type Eclipsing Binary BW Aquarii from K2 Campaign 3
Authors: Lester Kathryn V. , Gies Douglas R. 
Published: June 2018

Abstract
Eclipsing binaries are important tools for studying stellar evolution and stellar interiors. Their accurate fundamental parameters are used to test evolutionary models, and systems showing apsidal motion can also be used to test the model’s internal structure predictions. For this purpose, we present a photometric and spectroscopic analysis of the eclipsing binary BW Aquarii, an evolved F-type binary with slow apsidal motion. We model the K2 C3 light curve using the Eclipsing Light Curve code to determine several orbital and stellar parameters, as well as measure the eclipse times to determine updated apsidal motion parameters for the system. Furthermore, we obtain high-resolution spectra of BW Aqr using the CHIRON echelle spectrograph on the CTIO 1.5 m for radial velocity analysis. We then reconstruct the spectra of each component using Doppler tomography in order to determine the atmospheric parameters. We find that both components of BW Aqr are late F-type stars with M
1 = 1.365 ± 0.008 M
☉, M
2 = 1.483 ± 0.009 M
☉, and R
1 = 1.782 ± 0.021 R
☉, R
2 = 2.053 ± 0.020 R
☉. We then compare these results to the predictions of several stellar evolution models, finding that the models cannot reproduce the observed properties of both components at the same age.
Solar-cycle Variations of Meridional Flows in the Solar Convection Zone Using Helioseismic Methods
Authors: Lin Chia-Hsien , Chou Dean-Yi 
Published: June 2018

Abstract
The solar meridional flow is an axisymmetric flow in solar meridional planes, extending through the convection zone. Here we study its solar-cycle variations in the convection zone using SOHO/MDI helioseismic data from 1996 to 2010, including two solar minima and one maximum. The travel-time difference between northward and southward acoustic waves is related to the meridional flow along the wave path. Applying the ray approximation and the SOLA inversion method to the travel-time difference measured in a previous study, we obtain the meridional flow distributions in 0.67 ≤ r ≤ 0.96R
⊙ at the minimum and maximum. At the minimum, the flow has a three-layer structure: poleward in the upper convection zone, equatorward in the middle convection zone, and poleward again in the lower convection zone. The flow speed is close to zero within the error bar near the base of the convection zone. The flow distribution changes significantly from the minimum to the maximum. The change above 0.9R
⊙ shows two phenomena: first, the poleward flow speed is reduced at the maximum; second, an additional convergent flow centered at the active latitudes is generated at the maximum. These two phenomena are consistent with the surface meridional flow reported in previous studies. The change in flow extends all the way down to the base of the convection zone, and the pattern of the change below 0.9R
⊙ is more complicated. However, it is clear that the active latitudes play a role in the flow change: the changes in flow speed below and above the active latitudes have opposite signs. This suggests that magnetic fields could be responsible for the flow change.
Toward a Quantitative Comparison of Magnetic Field Extrapolations and Observed Coronal Loops
Authors: Warren Harry P. , Crump Nicholas A. , Ugarte-Urra Ignacio , Sun Xudong , Aschwanden Markus J. , Wiegelmann Thomas 
Published: June 2018

Abstract
It is widely believed that loops observed in the solar atmosphere trace out magnetic field lines. However, the degree to which magnetic field extrapolations yield field lines that actually do follow loops has yet to be studied systematically. In this paper, we apply three different extrapolation techniques—a simple potential model, a nonlinear force-free (NLFF) model based on photospheric vector data, and an NLFF model based on forward fitting magnetic sources with vertical currents—to 15 active regions that span a wide range of magnetic conditions. We use a distance metric to assess how well each of these models is able to match field lines to the 12202 loops traced in coronal images. These distances are typically 1″–2″. We also compute the misalignment angle between each traced loop and the local magnetic field vector, and find values of 5°–12°. We find that the NLFF models generally outperform the potential extrapolation on these metrics, although the differences between the different extrapolations are relatively small. The methodology that we employ for this study suggests a number of ways that both the extrapolations and loop identification can be improved.
Cysteine-Reactive Free ISG15 Generates IL-1β–Producing CD8α+ Dendritic Cells at the Site of Infection
Authors: Napolitano Anna , van der Veen Annemarthe G. , Bunyan Monique , Borg Annabel , Frith David , Howell Steven , Kjaer Svend , Beling Antje , Snijders Ambrosius P. , Knobeloch Klaus-Peter , Frickel Eva-Maria 
Published: June 2018

Abstract
IFN-stimulated gene (ISG) 15 is a ubiquitin-like protein induced after type I IFN stimulation. There is a dearth of in vivo models to study free unconjugated ISG15 function. We found that free ISG15 enhances the production of IFN-γ and IL-1β during murine infection with Toxoplasma gondii. In our model, ISG15 is induced in a type I IFN–dependent fashion and released into the serum. Increased ISG15 levels are dependent on an actively invading and replicating parasite. Two cysteine residues in the hinge domain are necessary determinants for ISG15 to induce increased cytokine levels during infection. Increased ISG15 is concurrent with an influx of IL-1β–producing CD8α+ dendritic cells to the site of infection. In this article, we present Toxoplasma infection as a novel in vivo murine model to study the immunomodulatory properties of free ISG15 and uniquely link it to IL-1β production by CD8α+ dendritic cells driven by two cysteines in the hinge region of the protein.
CK2 Controls Th17 and Regulatory T Cell Differentiation Through Inhibition of FoxO1
Authors: Gibson Sara A. , Yang Wei , Yan Zhaoqi , Qin Hongwei , Benveniste Etty N. 
Published: June 2018

Abstract
Growing evidence demonstrates that the highly conserved serine/threonine kinase CK2 promotes Th17 cell differentiation while suppressing the generation of Foxp3+ regulatory T cells (Tregs); however, the exact mechanism by which CK2 regulates the Th17/Treg axis remains unclear. CK2 can be composed of three distinct subunits: two catalytic subunits, CK2α and CK2α′, and the regulatory subunit CK2β. We generated mice that lack the major catalytic subunit of CK2, CK2α, specifically in mature T cells using the distal Lck-Cre (CK2α−/−). Importantly, CK2α deficiency resulted in a significant decrease in the overall kinase activity of CK2. Further, CK2α deficiency resulted in a significant defect in Th17 cell polarization and a reciprocal increase in Tregs both in vitro and in vivo in the context of autoimmune neuroinflammation. The transcription factor forkhead box protein O1 (FoxO1) directly inhibits Th17 cell differentiation and is essential for the generation of Tregs. CK2α−/− CD4+ T cells exhibit less phosphorylated FoxO1 and a corresponding increase in the transcription of FoxO1-regulated genes. Treatment of CK2α−/− CD4+ T cells with the FoxO1 inhibitor AS1842856 or short hairpin RNA knockdown of FoxO1 is sufficient to rescue Th17 cell polarization. Through use of a genetic approach to target CK2 kinase activity, the current study provides evidence of a major mechanism by which CK2 regulates the Th17/Treg axis through the inhibition of FoxO1.