bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paradox
Authors: Cuonzo Margaret 
Published: January 2019

An introduction to paradoxes showing that they are more than mere puzzles but can prompt new ways of thinking.
Thinkers have been fascinated by paradox since long before Aristotle grappled with Zeno's. In this volume in The MIT Press Essential Knowledge series, Margaret Cuonzo explores paradoxes and the strategies used to solve them. She finds that paradoxes are more than mere puzzles but can prompt new ways of thinking.
A paradox can be defined as a set of mutually inconsistent claims, each of which seems true. Paradoxes emerge not just in salons and ivory towers but in everyday life. (An Internet search for “paradox” brings forth a picture of an ashtray with a “no smoking” symbol inscribed on it.) Proposing solutions, Cuonzo writes, is a natural response to paradoxes. She invites us to rethink paradoxes by focusing on strategies for solving them, arguing that there is much to be learned from this, regardless of whether any of the more powerful paradoxes is even capable of solution.
Cuonzo offers a catalog of paradox-solving strategies—including the Preemptive-Strike (questioning the paradox itself), the Odd-Guy-Out (calling one of the assumptions into question), and the You-Can't-Get-There-from-Here (denying the validity of the reasoning). She argues that certain types of solutions work better in some contexts than others, and that as paradoxicality increases, the success of certain strategies grows more unlikely. Cuonzo shows that the processes of paradox generation and solution proposal are interesting and important ones. Discovering a paradox leads to advances in knowledge: new science often stems from attempts to solve paradoxes, and the concepts used in the new sciences lead to new paradoxes. As Niels Bohr wrote, “How wonderful that we have met with a paradox. Now we have some hope of making progress.”
Helicobacter pylori: transtornos neurológicos e oftalmológicos
Authors: Farooq Muhammad U , Bhatt Archit 
Published: January 2019

A infecção por Helicobacter pylori tem sido associada a muitas infecções intestinais e extra-intestinais. Tem sido relacionada com muitas doenças neurológicas e oftalmológicas, incluindo as doenças cerebrovasculares, enxaqueca, doença de Alzheimer, epilepsia, doença de Parkinson, esclerose múltipla, neuropatias periféricas, glaucoma, e neuropatia ótica isquêmica. Os mecanismos fisiopatológicos podem envolver vários processos imunológicos em resposta a um agente infeccioso ou diferentes antígenos liberados durante a destruição do tecido, resultando em ativação da imunidade celular e humoral; ativação e agregação plaquetária; diferentes substâncias vasoativas e inflamatórias; espécies reativas de oxigênio e processos apoptóticos. Os efeitos a longo prazo do H. pylori no curso desses transtornos ainda precisam ser explorados.
Treatment of primary cutaneous CD30‐positive anaplastic large cell lymphoma with Wenyang Shengji decoction and Huanglian ointment: A case report
Authors: Li Kai , Bao Tingting , Wei Ruonan , Yang Yingying , Kang Mengjiao , Zhang Wei , Zeng Xianyu , Duan Yiqun , Chen Liuqing , Zhao Linhua 
Published: November 2024

AbstractPrimary cutaneous CD30 positive anaplastic large cell lymphoma (PC‐ALCL) is a rare non‐Hodgkin's lymphoma. Combined chemotherapy regimens such as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), MACOP‐B (methotrexate, doxorubicin, cyclophosphamide, vincristine, prednisone, and bleomycin), or F‐MACHOP (5‐fluorouracil, methotrexate, cytosine‐arabinoside, cyclophosphamide, doxorubicin, vincristine, and prednisone) are often used for its clinical treatment. In this study, we reported a new treatment method using a traditional Chinese therapy involving oral Wenyang Shengji decoction (WSD) combined with Huanglian ointment applied externally in a 32‐year‐old female patient with PC‐ALCL. Introduction: A 32‐year‐old woman who complained of an ulcer on the forehead accompanied by significant pain. PC‐ALCL was diagnosed by histopathological examination and immunohistochemical analysis. Treatment plan: WSD was prepared in 300 mL water and administered orally as a 150 mL decoction twice daily, and Huanglian ointment was applied to the ulcer three times daily. After 8 weeks of treatment with WSD combined with Huanglian ointment, the lesion healed completely. Immunohistochemical analysis revealed the presence of scattered CD3+++, CD4++, CD8++, CD20++, and CD30‐positive cells. After 12 weeks of treatment, the ulcer healed completely, leaving only a marked pale red‐pitted scar. The patient was followed up for 3 years without recurrence and no adverse events. Conclusion: oral WSD combined with Huanglian ointment applied to the ulcer for PC‐ALCL can promote the healing of ulcers, reduce or alleviate the formation of scar, and eliminate CD30‐positive cells. This case report provides a reference for the clinical treatment of PC‐ALCL using traditional Chinese medicine.
Textile Hinges Enable Extreme Properties of Kirigami Metamaterials
Authors: Meeussen Anne S. , Bordiga Giovanni , Chang Audrey X. , Spoettling Ben , Becker Kaitlyn P. , Mahadevan L. , Bertoldi Katia 
Published: November 2024

AbstractMechanical metamaterials—structures with unusual properties that emerge from their internal architecture—that are designed to undergo large deformations typically exploit large internal rotations, and therefore, necessitate the incorporation of flexible hinges. Kirigami structures, made by introducing ordered cuts in a planar material, are one such example. In the mechanism limit, these structures consist of rigid bodies connected by ideal hinges that deform at zero energy cost. However, fabrication in this limit has remained elusive. Here, we demonstrate that the integration of textile hinges provides a scalable platform for creating large kirigami metamaterials with mechanism‐like behaviors. Further, leveraging recently introduced kinematic optimization tools, we show that textile hinges enable extreme shape‐morphing responses, paving the way for the next generation of mechanism‐based metamaterials.
X‐Ray‐Triggered CA IX Inhibition Nanoplatform Promotes Intratumoral Acidosis‐Induced Cancer Ferroptosis
Authors: You Yuanyuan , Jiang Wenxiao , Xu Renhao , He Junbing , Chen Tianfeng , Liu Qinghua 
Published: November 2024

AbstractRadiotherapy‐induced ferroptosis is accompanied by an adaptive response to the expression of tumor cell ferroptosis suppressor genes. Herein, a degradable and in situ generated silicomanganese composite system loaded with carbonic anhydrase (CA IX) inhibitor (4‐(2‐aminoethyl) benzenesulfonamide (ABS) is constructed to form a DSiMn‐ABS nanosystem to improve the ferroptosis sensitivity of hypoxic tumor cells and improve the radiotherapy effect. The system can be continuously degraded in the tumor environment and X‐rays, releasing Manganese dioxid （MnO2)and ABS; Thereby inhibiting the activity of CA IX, inducing acidification inside tumor cells, regulating the AMP‐activating protein kinase (AMPK)/Acetyl‐CoA carboxylase(ACC) axis to increase the sensitivity of tumor cells to ferroptosis, and depleting glutathione (GSH) through MnO2 influencing glutathione peroxidase 4 (GPX4) activity, which further inhibits the ferroptosis defense system of tumor cells, and ultimately effectively improves the therapeutic efficiency of radiotherapy. Ultimately, the system can effectively inhibit tumor growth. Therefore, this degradable system can utilize double‐sensitized radiotherapy to provide new ideas for tumor radiotherapy.
Room Temperature Pulsed Laser Deposition of Aluminum Zinc Oxide (AZO): Enabling Scalable Indium‐Free Transparent Conductive Oxides
Authors: Reinders Joost W. C. , Bolding Jons , Roldán‐Carmona Cristina , Ventosinos Federico , Paliwal Abhyuday , Gil‐Escrig Lidón , Palazon Francisco , Sessolo Michele , Zanoni Kassio P. S. , Bolink Henk J. 
Published: November 2024

AbstractIndium tin oxide (ITO) is the leading transparent electrode material in displays and in photovoltaics. As both these markets are vast and rapidly expanding, the demand for alternative transparent conductive oxides (TCOs) is becoming increasingly urgent due to the limited availability of indium. Herein, aluminum‐doped zinc oxide (AZO) is revisited as a promising indium‐free TCO candidate. An industrial‐scale pulsed laser deposition (PLD) process is developed that produces highly conductive and transparent AZO films at room temperature, without the need for post‐deposition annealing. This PLD‐AZO films have excellent morphological, electrical, and optical properties, with sheet resistances of ≈ 55–25 Ω ϒ−1 for thin TCO thicknesses (around 100 to 200 nm, respectively), and absorptance from 400 to 1000 nm below 10%. We demonstrate the application of this highly conductive PLD‐AZO not only as a bottom contact but also as an effective top contact in perovskite solar cells, highlighting its versatility. The AZO‐based devices achieve performance and stabilities equivalent to that of ITO‐based. This findings demonstrate the robustness and potential of PLD‐deposited AZO layers in enhancing displays and PV production and facilitating the wider adoption of renewable and sustainable TCO alternatives in the expanding photovoltaics and displays markets.
Bio‐Inspired Self‐Renewing Implant Surfaces With Sequential Biofunctional Adaptation for Infectious Diabetic Tissue Repair
Authors: Cui Bin , Wen Min , Cai Zhe , Si Yunhui , Liu Fei , Zheng Yufeng , Zhang Chao , Jia Zhaojun 
Published: November 2024

AbstractThe clinical success of bioinert, tissue‐interfacing metallic implants is greatly jeopardized by complications such as infections, inflammation, and poor regeneration or biointegration, especially concerning diabetics. Implants featuring self‐renewable surfaces that sequentially dictate antibacterial/anti‐inflammatory, immunomodulatory, and pro‐healing/‐regenerative functionalities represent an emerging solution. Herein, fusing triple marine bioinspirations, namely the multilayered interlocked interfaces of mollusk shells, the adhesive/reactive chemistries of mussels, and the self‐renewing, release‐active mucus layers of corals, a self‐adaptive interfacial engineering strategy that imparts self‐renovating surfaces and temporally‐activatable biofunctionalities to various inert biometallic devices is presented. Specifically, sandwich‐like multilayered coatings are in situ constructed, comprising a substrate‐derived micro/nanostructured prelayer, a mussel‐inspired bioadhesive interlayer, and a polyphenol–antibiotic dynamically‐crosslinked therapeutic gel toplayer. The dynamic bonds within the gel allowed pH/reactive oxygen species‐responsive surface degradation, localized release of multifunctional therapeutics, and conditional exposure of cell‐supportive chemical moieties and micro/nanotopographies. Systematic in‐vitro, in‐ovo, and in‐vivo (spanning osseous, subcutaneous, and wound‐closure implantations) studies demonstrated that the functionalized bone implants or wound closure staples possessed adaptive biocompatibility (cyto‐/hemo/‐tissue‐compatibility) and biofunctionalities to combat device‐associated infections and spur diabetic tissue repair. This study underscores the potential of self‐adaptive coating strategies for orchestrating complex (even contradictory) biological functions in addressing challenging medical conditions that require implant intervention.
Band Alignment Semimetal Heterojunction‐Based Ultrabroadband Photodetector for Noncontact Gesture Interaction with Low Latency
Authors: Lian Yunlu , Jia Shengwang , Yu He , Han Jiayue , Jiang Jiamin , Lan Changyong , Liu Xiaodong , Liao Yulong , Dong Xiang , Wang Yang , Gou Jun , Wu Zhiming , Jiang Yadong , Wang Jun 
Published: November 2024

AbstractNon‐contact gesture recognition and interaction (NGRI) revolutionizes the natural user interface, fundamentally transforming human interactions with daily‐use technology. Conventional NGRI systems frequently encounter obstacles such as pronounced latency and environmental disturbances, including humidity or lighting conditions, resulting in compromised system fluidity and robustness. This study highlights the utilization of silicon‐based semimetal heterojunction photodetectors for precise gesture recognition and seamless human‐machine interaction. Through the application of band alignment theory and sophisticated TCAD simulation, heterojunction barriers are successfully optimized by fine‐tuning parameters including Si doping concentration and semimetal thickness. By strategically aligning vertical material growth and implementing vertical heterojunction configuration, a room temperature detector with exceptional sensitivity (specific detectivity (D*): ≈1011 Jones), ultra‐broad spectral range (405–10600 nm), and rapid response time (≈ µs) is achieved. Harnessing its distinguished speed and sensitivity in detecting human infrared radiation, in conjunction with an advanced spatial‐temporal comparison algorithm and a multi‐channel high‐frequency sampling processing design, a NGRI system with low latency, high precision, minimal energy consumption, and versatility across diverse scenarios has been developed. The results pave the way for non‐contact sensor design and may further enhance the practicality and user experience of non‐contact human‐machine interaction systems.
Visible Light‐Triggered Self‐Welding Perovskite Solar Cells and Modules
Authors: Li Xiongjie , Ding Bin , Huang Junyi , Zhang Zhiguo , Dong Hongliang , Yu Haixuan , Liu Zhirong , Dai Letian , Shen Yan , Ding Yong , Dyson Paul J. , Nazeeruddin Mohammad Khaja , Wang Mingkui 
Published: November 2024

AbstractFlexible perovskite solar cells (F‐PSCs) are highly promising for both stationary and mobile applications because of their advantageous features, including mechanical flexibility, their lightweight and thin nature, and cost‐effectiveness. However, a number of drawbacks, such as mechanical instability, make their practical application difficult. Here, self‐welding dynamic diselenide that is triggered by visible light into the structure of F‐PSCs to improve their long‐term stability by repairing cracks and defects in the absorber layer is incorporated. The diselenide confers the flexibility and self‐welding properties to the Cs0.05MA0.05FA0.9PbI3 perovskite layer, enabling optimized F‐PSC devices to achieve a power conversion efficiency of 24.85% while retaining ca. 92% of their initial efficiency after undergoing 15 000 bending cycles at a curvature radius of 3 mm. The corresponding flexible large‐scale module with an active area of 15.82 cm2 achieved a record PCE of 21.65%.
Performance‐Oriented and Deformation‐Constrained Dual‐topology Metamaterial with High‐Stress Uniformity and Extraordinary Plastic Property
Authors: Guo Haoyuan , Zhang Jianxun 
Published: November 2024

AbstractThe study of classical mechanical metamaterials has overwhelmingly remained at the elastic stage, while the increase in extreme speeds of vehicles and aircraft has created an urgent need and demanding requirements for excellent plasticity performance. Although some plastically deformable metamaterials exist, high initial peak stresses, short plastic strokes, and low plastic stresses limit their applications considerably. Here, an ideal malleable large‐deformation metamaterial featuring high‐stress levels and stability is reported. A performance‐oriented multidimensional performance expansion strategy is adopted to obtain the bionic triangular corrugation‐based plate lattice (TCPL) metamaterial. Then, the deformation constraint strategy that TCPL is innovatively used as the main topology with lateral expansion and buckling inhibited by the inserted enhancing topology is proposed, thus obtaining the built‐in dual‐topology enhanced TCPL (ETCPL). The ETCPL is again substantially strengthened in stress uniformity with almost no gradient and mechanical properties with strain energy improved by 51.56%. They are much more robust than typical multicellular materials, with the largest performance enhancement reaching 18 667.19%. In addition, the strength‐density performances of both metamaterials significantly exceed the predictions of Gibson–Ashby model up to 75.2% maximum. The unprecedented performance confirms that multidimensional performance expansion strategy and deformation constraint strategy have created new design guidelines for ideal high‐performance plastic metamaterials.
Optimizing Si─O Conjugation to Enhance Interfacial Kinetics for Low‐Temperature Rechargeable Lithium‐Ion Batteries
Authors: Wang Yiwen , Liu Jie , Ji Haoqing , Wang Sai , Wang Mengfan , Zhou Xi , Qian Tao , Zheng Yiwei , Yan Chenglin 
Published: November 2024

AbstractWith the growing demand for high‐voltage and wide‐temperature range applications of lithium‐ion batteries (LIBs), the requirements for electrolytes have become increasingly stringent. While fluorination engineering has enhanced the performance of traditional solvent systems, it has also raised concerns regarding cost, environmental hazards, and low reduction stability. Through strategic molecular bond design, a novel class of low‐temperature (LT) solvents—siloxanes—is identified, meeting the demands of LT and high‐voltage applications in LIBs. The d‐p conjugation of the Si─O bond enhances voltage resistance and weakens the Li+‐solvent interactions. By modulating the number of Si─O conjugated bonds, the type of anion clusters in the solvation structure can be controlled, ultimately leading to the formation of a LiF and Si─O‐rich interfacial layer and facilitating rapid Li+ conduction. Consequently, the graphite||NCM811 pouch cell (2.3 Ah, 4.45 V) with a siloxane‐based electrolyte retains 75.1% of room temperature capacity (RTC) at −50 °C. The rapid interface kinetics allow a superior reversible charging capacity retention of 67.6% at −40 °C, with good cycle stability at −20 °C. This study provides new insights into solvent design to fortify LIB performance in harsh conditions.
Hyaluronic Acid‐Nanocoated Bacteria Generate an Anti‐Inflammatory Tissue‐Repair Effect in Impaired Gut and Extraintestinal Organs
Authors: Deng Bo , Lin Sisi , Wang Yu , Zhang Mengmeng , Shen Yuqi , Zhou Peihui , Shen Aiwen , Wang Lu , Ding Feng , Liu Jinyao 
Published: November 2024

AbstractDiverse extraintestinal diseases are characterized by localized inflammatory responses and tissue damage, accompanied with intestinal inflammation and injury. Here, a dual‐functionality and dual‐location intervention strategy is reported, which is the use of hyaluronic acid‐nanocoated Clostridium butyricum to generate an anti‐inflammatory tissue‐repair effect in the impaired gut and extraintestinal organs. Nanocoated bacteria attenuate intestinal mucosal inflammation and recover gut barrier integrity by leveraging the immunosuppressive nature of hyaluronic acid and the butyrate‐producing ability of Clostridium butyricum. Nanocoated bacteria also alleviate the interstitial inflammation and pathological damage of extraintestinal organs via remodeling microbial metabolites and decreasing microbial translocation. In murine models of acute kidney injury and chronic kidney disease, oral delivery of nanocoated bacteria demonstrates the potency to restore renal function and eliminate renal fibrosis. This work proposes a type of next‐generation living therapeutics for treating extraintestinal diseases.
Ultra‐Fast, Unidirectional Water Absorption on Wood Ear
Authors: Wang Yisha , Zhao Liurui , Luo Yu‐Qiong , Liu Lan , Li Yonghua , Yao Xi , Ju Jie , Jiang Lei 
Published: November 2024

AbstractMaterials exhibiting rapid, unidirectional liquid absorption are desirable for comfort textiles and wound dressings. Implementing chemical or structural gradient along the vertical axis of substrates is an effective way to achieve such properties. Liquid's lateral spreading across the substrate affects area occurring vertical imbibition. However, the influence of lateral spreading on liquid's overall absorption remains unexplored. Findings on ultra‐fast, unidirectional water absorption on the abhymenium of wood ear fungi are presented, featuring dense micro‐sized hairs atop a porous sublayer containing smaller micro‐/nano‐pores. These hairs facilitate lateral spreading, and the gradient‐sized structures from the surface hairs to the internal pores enhance capillary force, promoting efficient vertical imbibition. The synergistic wicking mechanism in both directions shortens absorption time of a 1‐µL droplet by two orders of magnitude compared to a solely porous surface (35 ms vs 5.2 s). An artificial micro‐pillar array on a porous substrate also exhibits ultra‐fast, unidirectional water absorption. This study advances the understanding of liquid dynamics in porous media and provides a blueprint for engineering materials with superior liquid management.
Adaptable Hydrogel with Strong Adhesion of Wet Tissue for Long‐Term Protection of Periodontitis Wound
Authors: Chen Honggui , Zhao Zifan , Zhang Rui , Zhang Guo , Liang Xiaoyang , Xu Chen , Sun Yuchun , Li Yang , Boyer Cyrille , Xu Fu‐Jian 
Published: November 2024

AbstractPeriodontitis is a severe gum infection characterized by inflammation of the tissues surrounding the teeth. The disease is challenging to manage due to its exposure to a wet and dynamic oral environment, where conventional hydrogels often suffer from weak adhesion, short residence time, and vulnerability to bacterial invasion. In this study, an innovative hydrogel system based on in situ light curing is proposed. The hydrogel precursor, comprising sodium alginate and a calcium ion network, is designed and adhere to the irregular and smooth surfaces of periodontal tissue before curing. Upon light irradiation, a second network polymerizes rapidly, establishing multiple interactions with the tissue, which enhances adhesion strength. Benefited from this engineering strategy, the hydrogel exhibits a low swelling rate, effectively mitigating adhesion loss in the moist oral environment. Additionally, the hydrogel demonstrates excellent long‐lasting wet adhesion, maintaining its presence in periodontal tissue over 120 hours. It also serves as an effective physical barrier against bacterial invasion, achieving a blocking efficiency of 99.9%. This novel design concept offers a promising approach for developing advanced medical dressings for periodontitis, providing sustained therapeutic benefits.
Tunable Multicolor Luminescence, Full‐Spectrum White‐Light Emission and Optical Temperature Sensing Based on Bi3+, Tb3+ and Eu3+ Doped Y4Al2O9 Nanofibers
Authors: Liu Xiaohan , Shao Hong , Li Ning , Teng Xue , Li Dan , Dong Xiangting , Zhang Hongbo 
Published: November 2024

AbstractThe realization of tunable multicolor luminescence especially full‐spectrum white‐light emission in a single matrix has aroused more attention from researchers. To address the above challenge, Bi3+, and Tb3+ are selected as both activators and sensitizers with the help of energy level matching engineering of Bi3+ and Tb3+ having matching energy levels with Eu3+, a series of 1D Y4Al2O9:Bi3+, Bi3+/Eu3+, Tb3+, Tb3+/Eu3+ and Bi3+/Tb3+/Eu3+ nanofibers (NFs) are designed and synthesized by a simple electrospinning technique combined with an oxidative calcination. Under 298‐nm UV light excitation, Y4Al2O9:Bi3+/Tb3+/Eu3+ NFs demonstrate tunable multicolor luminescence (blue, purple, red, green, yellow, and white) especially full‐spectrum white‐light emission via double energy transfer (ET) effect and modulation of molar ratio among Bi3+, Tb3+ and Eu3+. Additionally, Y4Al2O9:3%Bi3+/7%Tb3+/1%Eu3+ NFs are sensitive to temperature, and the maximum Sα and Sγ values of Y4Al2O9:3%Bi3+/7%Tb3+/1%Eu3+ NFs reach 0.0417 K−1 and 0.84% K−1, respectively. In virtue of electrospinning, triple activators (Bi3+, Tb3+, and Eu3+) are readily and uniformly doped in Y4Al2O9 NFs single matrix to achieve dual function of tunable multicolor luminescence and temperature sensing. The formation principle and luminescence theory of the samples are clarified. The findings in this work are instructive to develop multicolor luminescent phosphors and temperature‐sensing materials.