bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐term efficacy of drug coated balloons compared with new generation drug‐eluting stents for the treatment of de novo coronary artery lesions
Authors: Venetsanos Dimitrios , Lawesson Sofia Sederholm , Panayi Georgios , Tödt Tim , Berglund Ulf , Swahn Eva , Alfredsson Joakim 
Published: February 2018

AbstractBackgroundStudies comparing drug coated balloons (DCB) with new generation drug‐eluting stents (nDES) for the treatment of de novo coronary artery lesions are lacking.MethodsFrom 2009 to 2016, DCB or nDES used for treatment of de novo coronary lesions at our institution were included, in total 1,197 DEB and 6,458 nDES. We evaluated target lesions restenosis (TLR) and definite target lesion thrombosis (TLT). Propensity score modeling were utilized to study adjusted associations between treatment and outcomes.ResultsMedian follow‐up was 901days. DCB patients were older, with higher cardiovascular risk profile. Bailout stenting after DCB was performed in 8% of lesions. The cumulative rate of TLR and TLT was 7.0 vs. 4.9% and 0.2 vs. 0.8% for DCB vs. nDES, respectively. Before adjustment, DCB was associated with a higher risk of TLR [hazard ratio (HR) 1.44; 95% confidence interval (CI) 1.07–1.94] and a non‐significantly lower risk of TLT (HR 0.30; 95% CI 0.07–1.24), compared to nDES. In the propensity matched population consisted of 1,197 DCB and 1,197 nDES, treatment with DCB was associated with similar risk for TLR (adjusted HR 1.05; 95% CI 0.72–1.53) but significantly lower risk for TLT (adjusted HR 0.18; 95% CI 0.04–0.82) compared to nDES.ConclusionsTreatment with DCB was associated with a similar risk of TLR and a lower risk of definite TLT compared with nDES. In selected cases, DCB appears as a good alternative to nDES for the treatment of de novo coronary lesions.
Malignant transformation of phyllodes tumor: a case report and review of literature
Authors: Pornchai Suragit , Chirappapha Prakasit , Pipatsakulroj Wiriya , Lertsithichai Panuwat , Vassanasiri Watoo , Sitathanee Chomporn , Kongdan Youwanush , Sukarayothin Thongchai , Leesombatpaiboon Monchai 
Published: February 2018

Key Clinical MessageMalignant phyllodes may transform from benign phyllodes; low‐aggressive malignant phyllodes tumor is manageable by locally wide excision.
K3B6O9F3: A New Fluorooxoborate with Four Different Anionic Units
Authors: Han Guopeng , Shi Guoqiang , Wang Ying , Zhang Bingbing , Han Shujuan , Zhang Fangfang , Yang Zhihua , Pan Shilie 
Published: February 2018

AbstractK3B6O9F3, a first fluorooxoborate containing four different units, that is, [BO3]3−, [BO4]5−, [BO3F]4−, and [BO2F2]3−, has been designed and synthesized by two different routes. The unique anionic
[B6O9F3]3− layers avoid forming terminal oxygen atoms, which are beneficial to enlarge the band gap. The structure‐properties relationship of the title compound is discussed.
Ammonothermal Synthesis of Nitrides: Recent Developments and Future Perspectives
Authors: Häusler Jonas , Schnick Wolfgang 
Published: February 2018

AbstractNitrides represent an intriguing class of functional materials with a broad range of application fields. Within the past decade, the ammonothermal method became increasingly attractive for the synthesis and crystal growth of nitride materials. The ammonothermal approach proved to be eminently suitable for the growth of bulk III‐nitride semiconductors like GaN, and furthermore provided access to numerous ternary and multinary nitrides and oxonitrides with promising optical and electronic properties. In this minireview, we will shed light on the latest research findings covering the synthesis of nitrides by this method. An overview of synthesis strategies for binary, ternary, and multinary nitrides and oxonitrides, as well as their properties and potential applications will be given. The recent development of autoclave technologies for syntheses at high temperatures and pressures, in situ methods for investigations of crystallization processes, and solubility measurements by ultrasonic velocity experiments is briefly reviewed as well. In conclusion, challenges and future perspectives regarding the synthesis and crystal growth of novel nitrides, as well as the advancement of autoclave techniques are discussed.
Metal‐Free Geminal Difunctionalization of Diazocarbonyl Compounds: A One‐Pot Multicomponent Strategy for the Construction of α,β‐Diamino Carbonyl Derivatives
Authors: Zhu Dan , Yao Yuan , Zhao Rong , Liu Yang , Shi Lei 
Published: February 2018

AbstractAn unprecedented three‐component domino oxidative coupling of diazocompounds for the efficient synthesis of α‐azido‐β‐amino esters with non‐activated dimethylamino compounds and simple TMSN3 was achieved. The main features of this method include metal‐free catalysis, satisfactory functional group tolerance, general applicability in complex molecule architectures, and excellent diastereoselectivity in the presence of chiral auxiliaries. In addition, several related control experiments have been conducted to investigate the reaction mechanism.
Cooperative caching for content dissemination in vehicular networks
Authors: Akhavan Bitaghsir Saeid , Khonsari Ahmad 
Published: February 2018

SummaryThe explosive growth of mobile data traffic has made cellular operators to seek low‐cost alternatives for cellular traffic off‐loading. In this paper, we consider a content delivery network where a vehicular communication network composed of roadside units (RSUs) is integrated into a cellular network to serve as an off‐loading platform. Each RSU subjecting to its storage capacity caches a subset of the contents of the central content server. Allocating the suitable subset of contents in each RSU cache such that maximizes the hit ratio of vehicles requests is a problem of paramount value that is targeted in this study. First, we propose a centralized solution in which, we model the cache content placement problem as a submodular maximization problem and show that it is NP‐hard. Second, we propose a distributed cooperative caching scheme, in which RSUs in an area periodically share information about their contents locally and thus update their cache. To this end, we model the distributed caching problem as a strategic resource allocation game that achieves at least 50% of the optimal solution. Finally, we evaluate our scheme using simulation for urban mobility simulator under realistic conditions. On average, the results show an improvement of 8% in the hit ratio of the proposed method compared with other well‐known cache content placement approaches.
Parent emotion regulation socializes children's adaptive physiological regulation
Authors: Shih Emily W. , Quiñones‐Camacho Laura E. , Davis Elizabeth L. 
Published: February 2018

AbstractParenting practices play a major role in socializing children's developing regulatory abilities, but less is known about how parents’ regulatory abilities relate to children's healthy functioning. This study examined whether parents’ physiological and emotion regulation abilities corresponded to children's physiological and emotional responding to a structured laboratory‐based disappointment task. Ninety‐seven 3‐ to 7‐year‐olds (56 girls; M = 5.79 years) and one parent participated in a multi‐method assessment of parents’ and children's regulatory functioning. Direct (coaching children to use reappraisal) and indirect (resting physiology, dispositional use of reappraisal) aspects of parents’ regulatory abilities were assessed. As expected, an adaptive pattern of parent regulatory abilities composed of higher resting respiratory sinus arrhythmia, use of reappraisal, and coaching reappraisal was associated with children's physiological reactivity after a disappointment indicative of more effective physiological calming in a recovery context (increased parasympathetic activation). In contrast, parents’ regulatory abilities did not relate to changes in children's expressions of emotional distress.
Cut loose and run: The complex role of ADAM proteases during neural crest cell development
Authors: Alfandari Dominique , Taneyhill Lisa A. 
Published: February 2018

SummaryADAM metalloproteases have been shown to play critical roles during development. In this review, we will describe functional evidence that implicates ADAM proteins during the genesis, migration and differentiation of neural crest cells. We will restrict our analysis to the transmembrane ADAMs as other reviews have addressed the role of extracellular metalloproteases (Christian et al. [2013] Critical Reviews in Biochemistry and Molecular Biology 48:544–560). This review will describe advances that have been obtained mainly through the use of two vertebrate model systems, the frog, and avian embryos. The role of the principal substrates of ADAMs, the cadherins, has been extensively described in other reviews, most recently in (Cousin [1997] Mechanisms of Development 148:79–88; Taneyhill and Schiffmacher [2017] Genesis, 55). The function of ADAMs in the migration of other cell types, including the immune system, wound healing and cancer has been described previously in (Dreymueller et al. [2017] Mediators of Inflammation 2017: 9621724). Our goal is to illustrate both the importance of ADAMs in controlling neural crest behavior and how neural crest cells have helped us understand the molecular interactions, substrates, and functions of ADAM proteins in vivo.
Individual‐based model evaluation of using vaccinated hatchery fish to minimize disease spread in wild fish populations
Authors: Ivan Lori N. , Brenden Travis O. , Standish Isaac F. , Faisal Mohamed 
Published: February 2018

AbstractAlthough vaccination programs are routinely used in terrestrial environments to protect wild and captive populations against infectious disease, their use in fish populations has been limited to aquaculture/hatchery facilities. A major challenge to enacting a vaccination program for wild fish populations is how to efficiently vaccinate large numbers of susceptible individuals. One possible solution to this dilemma would be vaccinating hatchery‐propagated fish prior to their being stocked into infected systems, although the effectiveness of such a program is uncertain. We constructed a spatially explicit individual‐based model to evaluate the effectiveness of vaccinating hatchery‐propagated fish to protect wild Lake Michigan Chinook salmon Oncorhynchus tshawytscha against a disease exhibiting characteristics similar to viral hemorrhagic septicemia genotype IVb. Simulations tracked growth, movement, mortality, maturation, wild reproduction, and disease transmission during a 25‐yr time period. Disease states consisted of vaccinated, susceptible, infected, shedding (i.e., infectious), and recovered. Factors that were examined included level of clustering among at‐large individuals, infection probability, relationship between viral exposure and mortality, number of stocked individuals, whether recovered individuals could resume viral shedding, and disease initialization status. At an annual stocking level of 2.4 million Chinook salmon, vaccination decreased the percent of the population infected by 23–74% per year depending on the factors evaluated. Doubling the stocking level of vaccinated individuals resulted in similar levels of protection. The largest decrease in percent infected occurred under a condition of low infection probability, high exposure mortality, and high degree of clustering. The protection stemming from vaccination was just slightly smaller under conditions of high infection and high exposure mortality. Complete disease eradication only occurred when recovered individuals could not resume viral shedding. Under such conditions, vaccination sometimes was not even necessary for disease eradication. Our modeling efforts showed that a vaccination program based on immunizing hatchery‐propagated individuals prior to stocking may help protect wild fish populations, although disease eradication may be difficult to achieve when recovered individuals can resume shedding viral particles.
Hot‐Pressed Hybrid Electrodes Comprising Silver Nanowires and Conductive Polymers for Mechanically Robust, All‐Doctor‐Bladed Semitransparent Organic Solar Cells
Authors: Koppitz Manuel , Wegner Eduard , Rödlmeier Tobias , Colsmann Alexander 
Published: February 2018

AbstractFuture low‐cost, high‐throughput production of organic solar cells in roll‐to‐roll printing processes calls for all‐solution‐processable device architectures. Mechanical flexibility and robustness are mandatory to roll the solar foils during printing and to eventually comply with certain end‐user requirements. Here, we report on semitransparent organic solar cells, comprising top and bottom silver nanowire (AgNW) electrodes that were embedded into conductive poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS). The devices exhibited excellent robustness in bending experiments with radii of 5 and 2.5 mm as well as upon folding. To avoid short circuits from nanowires that could stick out of the bottom electrodes, the PEDOT:PSS:AgNW layers were flattened by hot‐pressing after deposition. All solar cells were fabricated in air by doctor blading and exhibited a clear (haze‐free) transparency due to the absence of bus bars. On photoactive areas of 0.5 cm2, power conversion efficiencies of 3.8 % were obtained.
An adaptive numerical scheme for solving incompressible 2‐phase and free‐surface flows
Authors: Frey P. , Kazerani D. , Ta T.T.M. 
Published: February 2018

SummaryIn this paper, we present a numerical scheme for solving 2‐phase or free‐surface flows. Here, the interface/free surface is modeled using the level‐set formulation, and the underlying mesh is adapted at each iteration of the flow solver. This adaptation allows us to obtain a precise approximation for the interface/free‐surface location. In addition, it enables us to solve the time‐discretized fluid equation only in the fluid domain in the case of free‐surface problems. Fluids here are considered incompressible. Therefore, their motion is described by the incompressible Navier‐Stokes equation, which is temporally discretized using the method of characteristics and is solved at each time iteration by a first‐order Lagrange‐Galerkin method. The level‐set function representing the interface/free surface satisfies an advection equation that is also solved using the method of characteristics. The algorithm is completed by some intermediate steps like the construction of a convenient initial level‐set function (redistancing) as well as the construction of a convenient flow for the level‐set advection equation. Numerical results are presented for both bifluid and free‐surface problems.
Adaptation or recovery after health shocks? Evidence using subjective and objective health measures
Authors: Baji Petra , Bíró Anikó 
Published: February 2018

SummaryIn this paper, we analyse the effect of an onset of a health shock on subjective survival probability and compare it with objective survival probability and self‐reported health measures. In particular, we are interested in whether expectations of people respond to health shocks and whether these follow the evolution of objective life expectations and self‐reported health measures over time. Using longitudinal data from the Health and Retirement Study, we estimate fixed effects models of adaptation for the objective and subjective survival probabilities and for some self‐reported health measures. The results show that after cancer diagnosis, conditional on surviving, both the objective and subjective longevity and self‐reported health measures drift back to the before diagnosis trajectories. For stroke and heart attack, in spite of their persistent negative effect on survival, subjective life expectations and self‐reported health measures seem to indicate only a transient effect of the health shock. The differences between the objective and subjective measures are in line with the concept of adaptation. We discuss the policy implications of our results.
Impact of the water salinity on the hydraulic conductivity of fen peat
Authors: Gosch Lennart , Janssen Manon , Lennartz Bernd 
Published: February 2018

AbstractCoastal peatlands represent an interface between marine and terrestrial ecosystems; their hydrology is affected by salt and fresh water inflow alike. Previous studies on bog peat have shown that pore water salinity can have an impact on the saturated hydraulic conductivity (Ks) of peat because of chemical pore dilation effects. In this study, we aimed at quantifying the impact of higher salinities (up to 3.5% NaCl) on Ks of fen peat. Two experiments employing a constant‐head upward‐flow permeameter and differing in measurement and salinity change duration were conducted. Additionally, a third experiment to determine the impact of water salinity on the release of dissolved organic carbon (DOC) of the studied peat type was carried out. The results show a decrease of Ks with time, which does not depend on the water salinity but is differently shaped for different peat types. We assume pore clogging due to a conglomerate of physical, chemical, and biological processes, which rather depend on water movement rate and time than on water salinity. However, an increased water salinity did increase the DOC release. We conclude that salinity‐dependent behaviour of Ks is a function of peat chemistry and that for some peat types, salinity may only affect the DOC release without having a pronounced impact on water flow.
TEMPERAMENTAL ADAPTABILITY, PERSISTENCE, AND REGULARITY: PARENTAL RATINGS OF NORWEGIAN INFANTS AGED 6 TO 12 MONTHS, WITH SOME IMPLICATIONS FOR PREVENTIVE PRACTICE
Authors: Olafsen Kåre S. , Ulvund Stein Erik , Torgersen Anne Mari , Wentzel‐Larsen Tore , Smith Lars , Moe Vibeke 
Published: February 2018

ABSTRACTThere is a need for standardized measures of infant temperament to strengthen current practices in prevention and early intervention. The present study provides Norwegian data on the Cameron‐Rice Infant Temperament Questionnaire (CRITQ; J.R. Cameron & D.C. Rice, 1986a), which comprises 46 items and is used within a U.S. health maintenance organization. The CRITQ was filled out by mothers and fathers at 6 and again at 12 months as part of a longitudinal study of mental health during the first years of life (the “Little in Norway” study, N = 1,041 families enrolled; V. Moe & L. Smith, 2010). Results showed that internal consistencies were comparable with U.S. data. The temperament dimensions of persistence, adaptability, and regularity had acceptable or close‐to‐acceptable reliabilities in the U.S. study as well as in this study, and also were unifactorial in confirmatory factor analysis. These dimensions are the focus in this article. Findings concerning parents’ differential ratings of their infants on the three dimensions are reported, as is the stability of parents’ ratings of temperament from 6 to 12 months. In addition, results on the relation between temperament and parenting stress are presented. The study suggests that temperamental adaptability, persistence, and regularity may be relevant when assessing infant behavior, and may be applied in systematic prevention trials for families with infants. The inclusion of concepts related to individual differences in response tendencies and regulatory efforts may broaden the understanding of parent—infant transactions, and thus enrich prevention and sensitizing interventions with the aim of assisting infants’ development.
Management of Patients With High Baseline Hip Fracture Risk by FRAX Reduces Hip Fractures—A Post Hoc Analysis of the SCOOP Study
Authors: McCloskey Eugene , Johansson Helena , Harvey Nicholas C , Shepstone Lee , Lenaghan Elizabeth , Fordham Ric , Harvey Ian , Howe Amanda , Cooper Cyrus , Clarke Shane , Gittoes Neil , Heawood Alison , Holland Richard , Marshall Tarnya , O'Neill Terence W , Peters Tim J , Redmond Niamh , Torgerson David , Kanis John A ,   the SCOOP Study Team
Published: February 2018

ABSTRACT

The Screening for Osteoporosis in Older Women for the Prevention of Fracture (SCOOP) study was a community-based screening intervention in women aged 70 to 85 years in the United Kingdom. In the screening arm, licensed osteoporosis treatments were recommended in women identified to be at high risk of hip fracture using the FRAX risk assessment tool (including bone mineral density measurement). In the control arm, standard care was provided. Screening led to a 28% reduction in hip fractures over 5 years. In this planned post hoc analysis, we wished to examine for interactions between screening effectiveness on fracture outcome (any, osteoporotic, and hip fractures) on the one hand and baseline FRAX 10-year probability of hip fracture on the other. All analyses were conducted on an intention-to-treat basis, based on the group to which women were randomized, irrespective of whether screening was completed. Of 12,483 eligible participants, 6233 women were randomized to screening, with treatment recommended in 898 (14.4%). No evidence of an effect or interaction was observed for the outcomes of any fracture or osteoporotic fracture. In the screening arm, 54 fewer hip fractures were observed than in the control arm (164 versus 218, 2.6% versus 3.5%), and commensurate with treatment being targeted to those at highest hip fracture risk, the effect on hip fracture increased with baseline FRAX hip fracture probability (p = 0.021 for interaction); for example, at the 10th percentile of baseline FRAX hip probability (2.6%), there was no evidence that hip fractures were reduced (hazard ratio [HR] = 0.93; 95% confidence interval [CI] 0.71 to 1.23), but at the 90th percentile (16.6%), there was a 33% reduction (HR = 0.67; 95% CI 0.53 to 0.84). Prior fracture and parental history of hip fracture positively influenced screening effectiveness on hip fracture risk. We conclude that women at high risk of hip fracture based on FRAX probability are responsive to appropriate osteoporosis management. © 2018 The Authors. Journal of Bone and Mineral Research Published by Wiley Periodicals, Inc.
Ascorbic acid—A black hole of urine chemistry screening
Authors: Unic Adriana , Nikolac Gabaj Nora , Miler Marijana , Culej Jelena , Lisac Adrijana , Horvat Anita , Vrkic Nada 
Published: February 2018

BackgroundStudy was performed in order: (i) to assess the comparability of glucose, bilirubin, hemoglobin, leukocyte esterase, and protein; (ii) to assess accuracy of glucose, bilirubin, hemoglobin, leukocyte esterase, and protein; and (iii) to evaluate interference of ascorbic acid on the glucose, bilirubin, hemoglobin, and nitrite determination using 2 different dipsticks: iChem Velocity, Iris Diagnostics and Combur‐10M, Roche Diagnostics.MethodsRandom urine specimens were included in the study. Comparability, accuracy, and ascorbic acid interference testing were performed.ResultsObtained results have shown almost perfect agreement for all parameters between 2 dipsticks in samples with negative ascorbic acid. Agreement in samples with positive ascorbic acid was not acceptable for bilirubin, protein, nitrite, and hemoglobin. Accuracy was not acceptable for hemoglobin and leukocyte esterase on both dipsticks. Ascorbic acid interference examination has shown that intensity of interference differs between dipsticks. Ascorbic acid interferes with glucose, hemoglobin, nitrite, and bilirubin at different concentrations causing false‐negative results.ConclusionObtained results indicate that it is necessary to determine diagnostic accuracy of used dipstick in order to define purpose of urinalysis. It is very important to choose dipstick with ascorbic acid indicator and to examine ascorbic acid impact on dipstick analytes independently of manufacturer claims.