bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social Meaning of Mangara Banua Tongkonan Ceremony in Toraja Society
Authors: Mukramin Sam'un , Ismail Lukman 
Published: April 2019

<p><em>As the background of this research, there was an existence of a mismatch between idealism and reality. Social change that lead to a negative change of Westernization or a change that lead to cultural destruction, but in reality therewere many cultures that had been preserved. In this case, the researchers studied the local culture that existed until now. For example, Mangrara Banua Tongkonan ceremony, the researchers saw that only the major of young generation in Tanah Toraja people knew specifically the meaning of Mangrara Banua Tongkonan Ceremony. </em><em>The type of research was descriptive qualitative research that a method in research the status of community, an object, an event. The location of this research was conducted in Ariang Village, Makale Sub-district, Tana Toraja Regency, with data collection technique were observation and interview with respondents .The results obtained about the meaning of social Mangrara Banua Tongkonan ceremony in Tana Torajawas analyzed descriptively qualitative, it can be concluded that the cause of Mangrara Banua Tongkonan ceremony was still preserved until now because of the value, tradition and the active participation of the community. While the meaning in Mangrara BanuaTongkonan ceremony was connotative and denotative meanings.</em></p>
Virtual training leads to real acute physical, cognitive and neural benefits on healthy adults: study protocol for a randomized-controlled trial
Authors: Burin Dalila , Yamaya Noriki , Ogitsu Rie , Kawashima Ryuta 
Published: April 2019

Abstract
BACKGROUND

Keeping a certain level of physical activity has beneficial effects on the body itself but also, surprisingly, on cognition: specifically, physical high-intensity intermittent aerobic exercise (HIE) can show improvement on cognitive executive functions. Although, in some cases performing strength or aerobic training is problematic or not feasible. Immersive virtual reality (IVR) can induce the illusory feeling of ownership and agency over a moving virtual body, showing therefore comparable physiological reactions: for example, if a subject is sitting on a chair but the own virtual body climbs a hill, the subject’s heart rate increases coherently, as if he’s actually walking.

In this study, we want to investigate whether this same illusion can show beneficial consequences on the body but also on executive functions (using the colour-word matching Stroop task) and on its neural substrates (using the functional near infrared spectroscopy, fNIRS).

METHODS

In a cross-over randomized controlled trial, 30 healthy young adults will experience a HIE training in IVR (i.e., the virtual body will perform eight sets of 30 seconds of running followed by 30 seconds of slow walking, while the subject is completely still) according to two random-ordered conditions: during the experimental condition, the virtual body is displayed in the first-person perspective (1PP), while in the control condition, the virtual body is displayed in third-person perspective (3PP). To confirm that in 1PP (and not in 3PP) subjects have the illusion of ownership and agency over the virtual body, we will record the heart rate, in addition to subjective questionnaires. Before and after every IVR sessions (one week apart), we will measure cortical hemodynamic changes in the participants’ prefrontal cortex (PFC) using the fNIRS device during the Stroop task’s execution.

DISCUSSION

From a theoretical perspective, we could prove that the sense of body ownership and agency can modulate physical and cognitive parameters, even in absence of actual movements; from a clinical perspective, these results could be useful to train cognition and body simultaneously, in a completely safe environment.

Trial registration
University Hospital Medical Information Network Clinical Trial Registry, UMIN000034255. Registered on 1st October 2018.
Nitrogen Fertilizer Management for Maize Production under Tropical Climate
Authors: Lucas Fábio Teixeira , Borges Bernardo Melo Montes Nogueira , Coutinho Edson Luiz Mendes 
Published: April 2019

Core Ideas
Untreated urea was as efficient as one treated with NBPT and DMPP.Maize yield was similar for split and single N application strategies.Critical level and maximum yield were reached at 110 and 185 kg ha−1 N.
High maize (Zea mays, L.) yields require an adequate supply of N fertilizer. As an alternative, fertilizers with nitrification and urease inhibitors have emerged onto the market to increase N supply to crops. The objective of this study was to determine the effects of urea treated with nitrification and urease inhibitors on plant growth and grain yield. The experiment was performed in a weathered tropical soil, in the 2013/2014 and 2014/2015 crop seasons. Fertilizer treatments were four N levels (0, 50, 100, and 200 kg ha−1 N); three urea treatments (urea with urease inhibitor: [N‐(N‐butyl) thiophosphoric triamide]–NBPT; urea with nitrification inhibitor: (3,4‐dimethylpyrazole‐phosphate)–DMPP; and conventional urea) and two application strategies (total N applied at sowing; and 30 kg ha−1 N at sowing and the remainder topdressed once plants had four completely developed leaves). Critical levels for chlorophyll index (CI), leaf N concentration, leaf area index (LAI), and N levels were 52.7, 27.5 g kg−1, 4.3 m2 m−2 and 110 kg ha−1, respectively. Addition of inhibitors and split N application did not increase growth, nutrition or yield compared to conventional urea and total N applied at sowing. However, increase of N levels increased grain yield by up to 185 kg ha−1 N. On the other hand, agronomic N use efficiency linearly decreased as N levels increased. It can be concluded that N sources and application strategies were not significant factors in grain yield. Therefore, N from conventional urea might be applied solely at sowing.
Estimation of Variance for Reciprocal General and Specific Combining Ability Effects by EM‐AI Algorithm
Authors: Marçal Tiago de S. , Rocha João R. do A. S. de C. , Salvador Felipe V. , dos Anjos Rafael S. R. , da Silva Adriel C. , Carneiro Pedro C. S. , Carneiro José E. de S. 
Published: April 2019

ABSTRACTIn diallel analysis, using mixed models, it is possible to estimate the variance components of general combining ability (GCA), specific combining ability (SCA), reciprocal GCA (RGCA), reciprocal SCA (RSCA), and parents, even in unbalanced datasets. These variances can be estimated by likelihood maximization via numerical algorithms (e.g., expectation maximization [EM] and average information [AI]), which have different advantages. Thus, the objective of this study was to describe and implement the EM‐AI algorithm (combination of EM and AI) in R software to estimate the variance components of RGCA, RSCA, and parents effects in diallel analysis. Two real datasets and three diallel models (Griffing's Model 1, Griffing's Model 1 + RGCA, and Model 3, a general diallel model with the effects of GCA, SCA, RGCA, RSCA, and parents) were used to evaluate the efficiency of the algorithms AI, EM, and EM‐AI. The AI algorithm failed to converge for the three diallel models in both datasets. The other algorithms (EM and EM‐AI) converged normally, and the estimated variance components with these algorithms were similar for the three diallel models in both datasets. However, the EM‐AI algorithm was more efficient than the EM algorithm, and the general diallel model (Model 3) provided more accurate estimates of variance parameters. Thus, the EM‐AI algorithm with routine implemented in R has potential for use in diallel analyses in plant breeding.
Fenomena Keterlantaran Suku Baduy di Pulau Jawa
Authors: Ngamanken Stephanus 
Published: April 2019

Baduy is a tribe that applies isolation from the outside world. They are not familiar with school, because school as formal education is opposed to their lifestyle. This study aims to explain the background and development of Baduy people whom are neglected, marginalized, and overlooked despite they live in Java island. The research method used is descriptive, case study type. The case is about why the Baduy tribe is neglected, marginalized, and overlooked. The Baduy tribe lives in Kanekes village, 39 km from Rangkasbitung city, 120 km from Jakarta. Data collecting uses interview and observation from January 2012 to June 2013. Data analysis uses qualitative data analysis technique. The results show five phenomena in the origin and development of the people which lead them to be neglected, marginalized, and overlooked. This study leads to conclusion that Baduy people need humanitarian assistance; and Paulo Freire’s conscience is one of the alternatives in providing humanitarian assistance to them.
Observing Hakka’s Culture According to Hakka’s Proverbs
Authors: Lim Sugiarto 
Published: April 2019

Proverbs in Hakka dialect reflect the attitude of the Hakka’s social life and nature. Hakka dialect’s proverbs are divided into two major categories of social life and natural phenomenon. This article tries to analyze how is the Hakkanese culture reflected by the characteristics of these two aspects. In aspects of social life, it could be seen the proverbs from several points of view, including the religion and traditional virtue, fame and academic, regional dialects, and feng shui. On the part of natural phenomenon, it could be seen Hakkanese dependency and understanding on the nature, as well as their agricultural production –based on their way of life and survival. The article is particularly concerned about the cultural characteristics of the Hakkanese which is shaped and reflected due to their migration history and root.
Activity Evaluation and Selection of Some Classes of Antibiotics with the use of Semi-Empirical Quantum Mechanics and Quantitative Structure- Activity Relationships Approach
Authors: Kawczak Piotr , Bober Leszek , Bączek Tomasz 
Published: April 2019

Background:
A set of β-lactam antibiotics, aminoglycoside antibiotics, and tetracycline
antibiotics were proposed and analyzed with the use of Quantitative Structure-Activity
Relationships (QSAR) method.

Objective:
The characterization of selected antimicrobial compounds in terms of both
physicochemical and pharmacological on the basis of calculations of quantum mechanics and
possessed biological activity data.

Methods:
During the study, Multiple Linear Regression (MLR) supported with Factor Analysis
(FA) and Principal Component Analysis (PCA) was made, as the types of proposed chemometric
approach; the semi-empirical level of in silico molecular modeling was used for calculations and
comparison of molecular descriptors both in a vacuum and in the aquatic environment.

Results:
The relationships between structure and microbiological activity enabled the
characterization and description of the analyzed molecules using statistically significant descriptors
belonging in most cases to different structural, geometric and electronic elements defining at the
same time the properties of the studied three different classes of examined antibiotics.

Conclusion:
The chemometric methods used revealed the influence of some of the elements of
structures examined molecules belonging to main antibiotics classes and responsible for the
antimicrobial activity.
Genome-wide Differential-based Analysis of the Relationship between DNA Methylation and Gene Expression in Cancer
Authors: Zhang Yuanyuan , Kou Chuanhua , Wang Shudong , Zhang Yulin 
Published: April 2019

Background::
DNA methylation is an epigenetic modification that plays an important
role in regulating gene expression. There is evidence that the hypermethylation of promoter regions
always causes gene silencing. However, how the methylation patterns of other regions in the
genome, such as gene body and 3’UTR, affect gene expression is unknown.

Objective::
The study aimed to fully explore the relationship between DNA methylation and expression
throughout the genome-wide analysis which is important in understanding the function of
DNA methylation essentially.

Method::
In this paper, we develop a heuristic framework to analyze the relationship between the
methylated change in different regions and that of the corresponding gene expression based on differential
analysis.

Results::
To understande the methylated function of different genomic regions, a gene is divided
into seven functional regions. By applying the method in five cancer datasets from the Synapse database,
it was found that methylated regions with a significant difference between cases and controls
were almost uniformly distributed in the seven regions of the genome. Also, the effect of
DNA methylation in different regions on gene expression was different. For example, there was a
higher percentage of positive relationships in 1stExon, gene body and 3’UTR than in TSS1500 and
TSS200. The functional analysis of genes with a significant positive and negative correlation between
DNA methylation and gene expression demonstrated the epigenetic mechanism of cancerassociated
genes.

Conclusion::
Differential based analysis helps us to recognize the change in DNA methylation and
how this change affects the change in gene expression. It provides a basis for further integrating
gene expression and DNA methylation data to identify disease-associated biomarkers.
Anti-Tumor Mechanisms of Novel 3-(4-Substituted Benzyl)-5-Isopropil-5- Phenylhydantoin Derivatives in Human Colon Cancer Cell Line
Authors: Obradović Ana , Matić Miloš , Ognjanović Branka , Vuković Nenad , Vukić Milena , Đurđević Predrag , Ušćumlić Gordana , Božić Bojan , Nedeljković Biljana B. 
Published: April 2019

Background:
Hydantoin and its newly synthesized derivatives have recently become a focus of interest
due to their numerous biological activities and newly emerging beneficial effects in different pathological
conditions, including cancer.

Objective:
The aim of this study was to evaluate the possible anti-tumor mechanisms of a series of newly synthesized
3-(4-substituted benzyl)-5-isopropyl-5-phenylhydantoin derivatives in different aspects of cell physiology
of human colon cancer cell line, HCT-116.

Methods:
The increasing concentrations of derivatives (0.01µM up to 100µM) were applied to cells during 24h,
48h, and 72h after which the evaluation of proliferation, apoptosis, oxidative/anti-oxidative status, nitrite production,
and migration/invasion potential of treated cells was performed.

Results:
All tested compounds expressed the dose- and time-dependent anti-proliferative and pro-apoptotic
activities against HCT-116 cells. The investigated derivatives induced a decrease in levels of oxidative stress
parameters and an increase in levels of nitrite production by treated cells suggesting their significant antioxidative
effects. The cell migration index and expression level of tumor invasion-promoting metalloproteinase-
9 (MMP-9) gene were significantly decreased after treatment with the tested hydantoin derivatives implicating
their inhibitory role in colon cancer cell motility and invasion processes. The mRNA level of cyclooxygenase-2
(COX-2) gene as a pro-inflammatory gene related to colorectal carcinogenesis was reduced compared to values
in the non-treated control cells indicating the significant anti-inflammatory/anti-tumor effects of these compounds.

Conclusion:
The obtained results show the significant anti-tumor potential of tested derivatives, especially 3-
benzyl-5-isopropyl-5-phenylhydantoin and 3-(4-chlorobenzyl)-5-isopropyl-5-phenylhydantoin, suggesting their
potential usage in the development of more effective chemotherapies.
Antioxidant Activities, Binding Parameters, and Electrochemical Behavior of Superoxide Anion Radicals Twords 1-Ferrocenylmethylthymine and 1-Ferrocenylmethylcytosine
Authors: Lanez Elhafnaoui , Bechki Lazhar , Lanez Touhami 
Published: April 2019

Background:
An electrochemical method based on cyclic voltametry techniques
was used to measure the antioxidant activity of two ferrocene-nucleobases.

Objective:
The present study aims to measure the antioxidant activity of two ferrocene derivatives
bearing nucleobases; the technique is based on the reaction of the in-situ electrochemical
generated superoxide anion radical with ferrocene-nucleobases.

Methods:
The decrease in the anodic peak current density of the O2 / O2
.− redox couple following
the addition of ferrocene-nucleobases was used to measure the antioxidant activity
and binding parameters of 1-ferrocenylmethylthymine and 1-ferrocenylmethylcytosine
with superoxide anion radical.

Conclusion:
Both 1-Ferrocenylmethylthymine and 1-Ferrocenylmethylcytosine showed
higher antioxidant activity (0.34 ± 0.03 and 0.045 ± 0.02 mg/mL respectively) than that of
standard antioxidant α-tocopherol (3.04 ± 0.03 mg/mL). The value of the binding free energy
ranging from -16.1 kJ.mol-1 for 1-ferrocenylmethylthymine to -21.8 kJ.mol-1 for 1-
ferrocenylmethylcytosine suggests an electrostatic interaction of superoxide anion radical
with both compounds which has been found to be the dominant interaction mode. The kinetics
of the interaction reaction of the compounds was quantified having second-order rate
constant values equal to 4.0 and 16.5 M-1 s-1 respectively.
Estrategias educativas para mejorar el aprendizaje del alumno en el módulo ‘Técnicas de Estudio en Ambientes Virtuales’
Authors: Hernández García Verónica , González Hernández Blanca Rosa , Andrade Guevara Cristina 
Published: April 2019

<p>Como institución, resulta de suma importancia ofrecer un apoyo extra al estudiante que incursiona en este ambiente virtual de aprendizaje, con el fin de que cuente con las herramientas y habilidades necesarias para culminar sus estudios de bachillerato. </p><p>Por lo anterior, en la Universidad Virtual del Estado de Guanajuato (UVEG) se considera, dentro de la trayectoria curricular, el Módulo Técnicas de Estudio en Ambientes Virtuales, el cual tiene como propósito que los estudiantes ‘se cambien el chip’ del ambiente presencial al virtual. </p><p>Al ser parte fundamental del desarrollo de sus ‘habilidades virtuales’, este Módulo se reviste de una importancia particular al estar diseñado para ayudar a los estudiantes a lograr aprendizajes prácticos que les serán útiles durante la educación media superior. </p><p>Debido a lo anterior y a la importancia de esta asignatura, el porcentaje de aprobación y los índices de inactividad son indicadores vitales para el seguimiento de los estudiantes que comienzan en este modelo. Esta investigación se enfoca en las estrategias que se han establecido para incrementar dichos indicadores.</p>
Acompañamiento a estudiantes del Bachillerato UDG virtual desde el programa institucional de tutoría
Authors: Godínez González Luz Del Carmen , Ochoa Reynoso Rosa Marcela , Matías Hernández Reymundo 
Published: April 2019

<p>La tutoría, entendida como un proceso de acompañamiento con los estudiantes a lo largo de su trayectoria académica desde una perspectiva de formación integral, puede aportar elementos de valor e impacto no sólo en los indicadores de retención, acreditación y eficiencia terminal de un programa educativo, sino también en la experiencia personal de aprendizaje. </p><p>En el presente trabajo exponemos la experiencia de tres tutores de trayectoria con estudiantes del Bachillerato General por Áreas Interdisciplinarias, en opción virtual. </p><p>La acción tutorial, como proceso de acompañamiento cercano, oportuno, claro y pertinente con los estudiantes, a través de estrategias que promuevan el desarrollo de habilidades y talentos, regulación del proceso de aprendizaje y generación de redes de apoyo entre los estudiantes, favorece la experiencia educativa y el desarrollo de aprendizaje y competencias en nuestros tutorados.</p>
El uso de redes sociales en el aprendizaje a distancia: metasíntesis
Authors: Mnkandla Ernest , Minnaar Ansie 
Published: April 2019

<p>La aceptación de las redes sociales en el aprendizaje en línea supone el final de la educación a distancia como la conocemos en la educación superior, aunque en apariencia han tenido un impacto mínimo en la forma en que las instituciones de educación abierta y a distancia (<em>ODL, por sus siglas en inglés</em>) están funcionando. Investigaciones anteriores sugieren que parte de la explicación para la lentitud en la aceptación de las redes sociales en el aprendizaje en línea está más allá de factores convencionales atribuidos a las reformas en la educación a distancia. </p><p>Esta investigación utiliza el marco conceptual para el aprendizaje en línea (<em>OCL, por sus siglas en inglés</em>) en la educación superior. Las redes sociales como los blogs, las wikis, el Skype y Google Hangouts, Facebook e incluso aplicaciones móviles como WhatsApp, podrían facilitar el aprendizaje y la creación de conocimiento en</p><p>el aprendizaje en línea para las instituciones de educación superior. </p><p>Nuestra metasíntesis es una integración interpretativa de los resultados de investigaciones cualitativas evaluadas por pares acerca de las redes sociales en el aprendizaje en línea. Incluye una síntesis de datos, métodos de investigación y teorías utilizadas para investigar redes sociales dentro de la educación en línea. Siete temas surgieron a partir de estos datos, los cuales han sido reformulados en un marco enfocado a redes sociales en el aprendizaje en línea como el producto final. El marco propuesto podrá ser útil para los diseñadores instruccionales y académicos que estén interesados en utilizar teorías de aprendizaje modernas y deseen adaptar las redes sociales en el aprendizaje en línea dentro de la educación superior como una estrategia de aprendizaje profundo.</p><p> --</p><p><strong>Este artículo ha sido reproducido de la Revista <em>The International Review of Research in Open and Distributed Learning (IRRODL). </em>Volumen 18, Número 5; utilizando una <em>licencia Creative Commons Attribution International 4.0</em>. © 2017 Autores: Ernest Mnkandla yAnsie Minnaar.</strong></p>
Rhodotorula glutinis y R. Rubra: agentes de micosis oportunistas en el hombre
Authors: Silva Julio , Runco de Laborda Rosa , Almendro Gladys , Salim Raquel 
Published: April 2019

Las levaduras del género Rhodotorula son patógenas potenciales para el hombre cuando este presenta las condiciones de terreno propicias para las micosis oportunistas. El presente trabajo tiene la finalidad de informar el aislamiento en cultivos puros y reiterados de estas levaduras en materiales clínicos de pacientes inmunocomprometidos.De 280 muestras clínicas diversas se aislaron 4 cepas correspondientes a Rhodotorula rubra y 1 a R. glutinis.Es posible relacionar la presencia de Rhodotorula con acción patógena en los materiales clínicos estudiados en pacientes con severo compromiso renal.
ESPIANDO PELO BURACO DA FECHADURA: AMBIENTE E FORMAÇÃO SUBJETIVA NAS MEMÓRIAS DE UMA CATADORA DE MATERIAL RECICLADO
Authors: Faria Rodrigo , De Souza Fonseca Giselle Rôças , Rodrigues de Oliveira Luiza , Brandão dos Anjos1 Maylta 
Published: April 2019

Trata-se do relato de parte de uma pesquisa, que analisa as relações entre os conceitos de memória cultural e de ambiente. Entrevistamos uma catadora de material reciclado, a fim de entender como o conceito de ambiente se institui na narrativa de suas memórias. Porém, a dialogia do encontro entre a entrevistada e os pesquisadores instituiu um recorte específico para o tema, representado pela tríade memória - formação subjetiva - ambiente. Neste relato apresentamos as discussões acerca desse momento da pesquisa, em que o conceito de ambiente está sendo pensando a partir das interações com o conceito de formação subjetiva. Para tanto, o aporte teórico é constituído pela abordagem histórico-cultural, que neste artigo é representada pelos encontros de diferentes autores, cuja aproximação se dá pelo conceito de sujeito histórico. Esses autores são: Vigotski, Pollak, Bakhtin e Freire. Essa interação com outros saberes vem sendo uma aposta da psicologia que vem sendo produzida contemporaneamente.