bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social and Clinical Impact of Congenital Urological Malformations in a Developing Country: The Need for a Transdisciplinary Way of Treatment
Authors: Fernández Nicolás , Puerto Niño Angie , Arreaza Kaufman Dan Jaim , Gracia Gloria , Ibañez Lina , Acevedo Carolina , Zarante Ignacio 
Published: December 2018

Introduction The prognosis of congenital anomalies (CAs) can be improved if detected and treated accurately. Given the complexity of some anomalies, it is almost always necessary to approach them with an interdisciplinary team. Our objective was to contact patients with congenital urological anomalies (CUAs) and follow them up during their first years of life and evaluate their clinical status, as well as their social and health care limitations.
Method Based on the Bogota Congenital Malformations Surveillance Program (BCMSP), we have contacted by phone all the patients with CUAs and evaluated their follow-up. We have included all the registered patients from 2006 until 2015. A standardized questionnaire was applied by a trained staff. The questions assessed on each call included: evaluation of the clinical status of the patient, the clinical treatments and evaluations performed by clinical and surgical subspecialties, health care limitations, and social barriers. The first call was made at the 2nd month, then every 3 months during the 1st year and every 6 months thereafter.
Results A total of 277 patients were contacted, 97.3% of whom have an increased risk of mortality or significant disability. The malformation related mortality was of 38.1%. Only 38.7% of the patients were evaluated by a specialist, while 57.4% where still waiting to be seen by a specialist. Ninety eight percent of the limitations related to the health care system were the long waiting lists to be seen by a specialist.
Conclusion Many of the pathologies that we have found belong to the group that has a significant reduction in mortality when treated accurately and promptly. However, we have a profound problem in our health care system, in that many of the patients have not been seen by a specialist, which results in a worse prognosis and recovery rate.
2D and 3D simulations of the permanent magnet undulator for generation of MIR-FEL
Authors: Kongmali K , Kitisri P , Rimjaem S 
Published: December 2018

Abstract
This research focuses on computer modelling and magnetic field simulations of the permanent magnet undulator at the PBP-CMU Electron Linac Laboratory, Chiang Mai University. This undulator magnet will be used for generation of the mid infrared free electron laser (MIR-FEL). It has 40 periods with a period length of 40 mm. The magnetic field simulations were conducted by using computer programs PANDIRA and RADIA for 2D and 3D models, respectively. The simulation results obtained from both models are presented and discussed in this paper. The magnetic field can be varied by adjusting a gap of the undulator. A maximum magnetic field of 0.23 Tesla can be achieved for the undulator gap of 26 mm. The simulated magnetic field distributions along the undulator magnetic axis obtained from the 3D model were used to calculate the deflecting angle and trajectory of electron. The achievement of this study will be used as a significant information for further installation and operation of the undulator magnet at our facility.
Quasi-isometries on subsets of 𝐶₀(𝐾) and 𝐶₀⁽¹⁾(𝐾) spaces which determine 𝐾
Authors: Galego Elói , da Silva André 
Published: December 2018

We introduce the concept of Banach-Stone subsets of

C

0

(
K
)

C_{0}(K)

spaces. This allows us to unify and improve several extensions of the classical theorem due to Banach (1933) and Stone (1937). More precisely, we prove that if

K
K

and

S
S

are locally compact Hausdorff spaces,

A
A

and

B
B

are Banach-Stone subsets of

C

0

(
K
)

C_{0}(K)

and

C

0

(
S
)

C_{0}(S)

, respectively, and there exists a map

T
T

from

A
A

to

B
B

(not necessarily injective) with image

θ
\theta

-dense in

B
B

for some

θ
>
0

\theta >0

such that

1
M

‖
f
−
g
‖
−
L
≤
‖
T
(
f
)
−
T
(
g
)
‖
≤
M
‖
f
−
g
‖
+
L
,

\begin{equation*} \frac {1}{M} \|f-g\|-L \leq \|T(f)-T(g)\|\leq M \|f-g\|+L, \end{equation*}

for every

f
,
g
∈
A

f, g \in A

, then

K
K

and

S
S

are homeomorphic whenever

L
≥
0

L \geq 0

and

M
>

2

M> \sqrt {2}

. As an application of this more general theorem concerning the quasi-isometries

T
T

on subsets of

C

0

(
K
)

C_{0}(K)

spaces, we show that certain quasi-isometries on

C
0

(
1
)

(
K
)

C_0^{(1)}(K)

spaces also determine the locally compact subspaces

K
K

of the real line

R

\mathbb R

with no isolated points. In turn, this result enables us to prove a unification and improvement of some theorems of Cambern, Pathak, and Vasavada for the first time to the nonlinear case.
An explicit Gross–Zagier formula related to the Sylvester conjecture
Authors: Hu Yueke , Shu Jie , Yin Hongbo 
Published: December 2018

Let

p
≡
4
,
7

m
o
d

9

p\equiv 4,7\ \mathrm {mod}\ 9

be a rational prime number such that

3

m
o
d

p

3\ \mathrm {mod}\ p

is not a cube. In this paper, we prove the

3
3

-part of

|

III

(

E
p

)

|

⋅

|

III

(

E

3

p
2

)

|

|\textrm {III}(E_p)|\cdot |\textrm {III}(E_{3p^2})|

is as predicted by the Birch and Swinnerton-Dyer conjecture, where

E
p

:

x
3

+

y
3

=
p

E_p: x^3+y^3=p

and

E

3

p
2

:

x
3

+

y
3

=
3

p
2

E_{3p^2}: x^3+y^3=3p^2

are the elliptic curves related to the Sylvester conjecture and cube sum problems.
Neural Coding of Contact Events in Somatosensory Cortex
Authors: Callier Thierri , Suresh Aneesha K , Bensmaia Sliman J 
Published: December 2018

Abstract
Manual interactions with objects require precise and rapid feedback about contact events. These tactile signals are integrated with motor plans throughout the neuraxis to achieve dexterous object manipulation. To better understand the role of somatosensory cortex in interactions with objects, we measured, using chronically implanted arrays of electrodes, the responses of populations of somatosensory neurons to skin indentations designed to simulate the initiation, maintenance, and termination of contact with an object. First, we find that the responses of somatosensory neurons to contact onset and offset dwarf their responses to maintenance of contact. Second, we show that these responses rapidly and reliably encode features of the simulated contact events—their timing, location, and strength—and can account for the animals’ performance in an amplitude discrimination task. Third, we demonstrate that the spatiotemporal dynamics of the population response in cortex mirror those of the population response in the nerves. We conclude that the responses of populations of somatosensory neurons are well suited to encode contact transients and are consistent with a role of somatosensory cortex in signaling transitions between task subgoals.
Toxoplasmosis: The Heart of the Diagnosis
Authors: England James H , Bailin Samuel S , Gehlhausen Jeffrey R , Rubin Donald H 
Published: December 2018

Abstract
Toxoplasma gondii is a common parasite that infects warm-blooded animals, including humans, and is a foodborne pathogen. We report a case of acute toxoplasmosis in a 76-year-old man after ingestion of the undercooked heart of a white-tailed deer (Odocoileus virginianus) in Tennessee. The patient’s adult grandson, who also consumed part of the heart, became ill with nearly identical symptoms, though he did not seek medical care. This case highlights important public health concerns about deer-to-human transmission of Toxoplasma.
A two-injection prostaglandin F2α presynchronization treatment decreases pregnancy rates of cycling replacement beef heifers
Authors: Monn Ruby E , Poole Rebecca K , Mackey J Christopher , Mayberry Kyle J , Dudley Harrison B , Alley Mark , Poole Daniel H 
Published: December 2018

Abstract
Improving artificial insemination (AI) pregnancy rates in replacement heifers improves the genetic advancement within a herd. Heifers that have completed at least three estrous cycles prior to breeding have greater pregnancy rates compared to acyclic females. Therefore, it was hypothesized that a presynchronization treatment program consisting of two injections of prostaglandin F2α (PGF2α) prior to the start of the CO-Synch + 5 d CIDR protocol would initiate earlier attainment of puberty and more estrous cycles prior to AI, thus increasing AI pregnancy rates. All heifers were managed the same at two locations over the course of 2 yr. Heifers were randomly assigned to receive either the two-injection PGF2α presynchronization treatment (PreSynch; n = 105) or no presynchronization (Control; n = 106) prior to the start of estrous synchronization. On the first day of the trial, reproductive tract scores (RTSs), pelvic areas, body condition scores, and weights were collected on all heifers. All heifers were synchronized with the CO-Synch + 5 d CIDR protocol and fixed-time artificially inseminated with semen from a bull of known fertility. Blood samples were collected three consecutive times at 7 d intervals starting 45 d prior to estrous synchronization to determine the onset of puberty via analyzing progesterone concentrations. Pregnancy status to AI was assessed using ultrasonography diagnosis at approximately 30 and 60 d post insemination. Data were analyzed using PROC MIXED of SAS and reported as least square mean. The PreSynch treatment decreased AI pregnancy rates (52.2% vs. 38.1 ± 6.3% for Control vs. PreSynch, respectively; P = 0.06) and did not result in earlier attainment of puberty in beef heifers (P &gt; 0.05). The PreSynch treatment did not impact pregnancy rates in heifers with an RTS of 3 or 4 (P &gt; 0.05). However, PreSynch heifers with an RTS of 5 had decreased pregnancy rates (68.3% vs. 46.9 ± 10.1% for Control vs. PreSynch, respectively; P &lt; 0.05). Finally, PreSynch heifers with increased body condition of 6 had decreased pregnancy rates when compared to Control heifers (37.5% vs. 62.5 ± 11.6%, respectively; P &lt; 0.05). On the basis of these data, implementation of heifer breeding soundness examination at least 3 wk prior to the start of the breeding season may be beneficial for selecting replacement females; however, presynchronization with prostaglandins immediately prior to estrous synchronization will negatively affect AI pregnancy rates in cycling pubertal heifers.
Learning Electromagnetic Navigational Bronchoscopy and Percutaneous Transthoracic Needle Biopsy (LEAP)
Authors: Lee Hans J. , Lerner Andrew D. , Coleman Briana , Semaan Roy , Mallow Christopher , Arias Sixto , Salwen Ben , Feller-Kopman David , Yarmus Lonny 
Published: December 2018

Background:
Prior studies in pulmonology have examined the validity of procedural training tools, however, translation of simulation skill acquisition into real world competency remains understudied. We examine an assessment process with a simulation training course for electromagnetic navigational (EMN) bronchoscopy and percutaneous transthoracic needle aspiration (PTTNA).

Methods:
A cohort study was conducted by subjects using EMN bronchoscopy and PTTNA. A procedural assessment tool was developed to measure basic competency for EMN bronchoscopy and PTTNA at 3 different time points: first simulation case, final simulation case upon reaching a competent score, and at their first live case. The assessment tool was divided into 4 domains (total score, 4 to 16; competency ≥12) with each domain requiring a passing score (1 to 4; competency ≥3.0). Complication and procedural time were collected during their first live case.

Results:
Twenty-two serial procedures (12 EMN bronchoscopies, 10 EMN PTTNA) were observed by 14 subjects. The mean first simulation score for EMN bronchoscopy (4.66±0.89) improved after cadaver simulation (12.67±0.89, median 3 simulations attempts). The subjects’ mean score for their first live case was 13.0±0.85 (self-reported score 12.5±1.07). For EMN PTTNA, the mean first simulation score (4.3±2.40) improved after cadaver simulation (12.6±1.51, median 3 simulation attempts). The subjects’ mean score for their first live PTTNA case was 12.5±2.87 (self-reported score 12.1±1.05). There was only 1 minor complication.

Conclusion:
Learning EMN bronchoscopy/PTTNA is feasible using a structured simulation course with an assessment tool.
Standing Tall: Feasibility of a Modified Ride-On Car That Encourages Standing
Authors: Logan Samuel W. , Catena Michele Ann , Sabet Andrina , Hospodar Christina M. , Yohn Haley , Govindan Aparna , Galloway James C. 
Published: December 2018

Purpose:
The purpose of this study was to determine the feasibility of infants with Down syndrome to use a modified ride-on car with seated and standing modes.

Methods:
Participants included 4 infants with Down syndrome. Families were asked to provide at least 8 minutes of modified ride-on car driving per day, at least 5 times per week throughout the 9-month intervention.

Results and Conclusions:
Families demonstrated a variety of adherence rates to the intervention. Infants demonstrated independent activation of the modified ride-on car in seated and standing modes and enjoyed driving. The modified ride-on car intervention was feasible and warrants further testing to address barriers that influence adherence to the intervention.
The Cost of Appearing Suspicious? Information Gathering in Trust Decisions
Authors: Ma I. , Sanfey A. G. , Ma W.J. 
Published: December 2018

ABSTRACTTrust decisions are inherently uncertain, as people have incomplete information about the trustworthiness of the other prior to their decision. Therefore, it is beneficial to gather information about a trustee’s past behaviour before deciding whether or not to trust them. However, elaborate inquiries about a trustee’s behavior may change the trustee’s willingness to reciprocate, causing either a decrease due to the investor appearing suspicious, or an increase because the investor appears to be highly betrayal-averse. Such a change could cause the investor to gather less or more information, respectively. We examine how information acquisition is modulated by social context, monetary cost, and the trustee’s trustworthiness. Participants had the opportunity to sequentially sample information about a trustee’s reciprocation history before they decided whether or not to invest. On some trials, we induced a social context by telling the participant that the trustee would later learn how much the participant sampled (“overt sampling”). Participants sampled less when there was a monetary cost and when the reciprocation history was more conclusive. Crucially, when sampling was free and overt, participants sampled less, suggesting negative consequences of appearing suspicious. In post-experiment questionnaires, participants indeed reported a belief that the reciprocation probability would decrease when information was overtly sampled. The findings replicated in a second experiment and were well accounted for by a utility-maximizing model in which overt sampling induces a decrease in reciprocation probability. This study opens the door to broader applications of the tools and models of information sampling to social decision-making.Significance StatementTrust and reciprocity are essential for establishing and maintaining beneficial cooperative interactions. However, not everyone can be trusted. Here, we focus on a fundamental question in the study of social interaction: how people gather and use information to make a decision to trust or not trust. While more information seems better, participants gathered less information about trustworthiness when the trustee would learn about the inquiries, as if they avoided appearing suspicious. Indeed, participants reported that they believed that sampling elaborately would make the trustee less willing to reciprocate trust. Using a mathematical model of information gathering, we show that this belief indeed reduces the value of information. Our findings contribute to a deeper understanding of information gathering in social contexts.
DRD2andFOXP2are implicated in the associations between computerized device use and psychiatric disorders
Authors: Wendt Frank R , Carvalho Carolina Muniz , Gelernter Joel , Polimanti Renato 
Published: December 2018

1.AbstractThe societal health effects of ubiquitous computerized device use (CDU) is mostly unknown. Epidemiological evidence supports associations between CDU and psychiatric traits, but the underlying biological mechanisms are unclear. We investigated genetic overlaps, causal relationships, and molecular pathways shared between these traits using genome-wide data regarding CDU (UK Biobank; up to N=361,194 individuals) and Psychiatric Genomics Consortium phenotypes (14,477<N<150,064). The strongest genetic correlations were between “weekly usage of mobile phone in last 3 months” (PhoneUse)vs. attention deficit hyperactivity disorder (ADHD) (rg=0.425, p=4.59x10-11) and “plays computer games” (CompGaming)vs. schizophrenia (SCZ) (rg=-0.271, p=7.16x10-26). Latent causal variable analysis did not support causal relationships between these traits, but the observed genetic overlap was related to shared molecular pathways, including: dopamine transport (Gene Ontology:0015872, pSCZvsCompGaming=2.74x10-10) andDRD2association (pSCZ=7.94x10-8; pCompGaming=3.98x10-25), andFOXP2association (pADHD=9.32x10-7; pPhoneUse=9.00x10-11). Our results support epidemiological observations with genetic data, and uncover biological mechanisms underlying psychiatric disorders contribution to CDUs.
PLANT-Dx: A Molecular Diagnostic for Point of Use Detection of Plant Pathogens
Authors: Verosloff M. , Chappell J. , Perry K. L. , Thompson J. R. , Lucks J. B. 
Published: December 2018

AbstractSynthetic biology based diagnostic technologies have improved upon gold standard diagnostic methodologies by decreasing cost, increasing accuracy, and enhancing portability. However there has been little effort in adapting these technologies towards applications related to point-of-use monitoring of plant and crop health. Here, we take a step towards this vision by developing an approach that couples isothermal amplification of specific plant pathogen genomic sequences with customizable synthetic RNA regulators that are designed to trigger the production of a colorimetric output in cell-free gene expression reactions. We demonstrate our system can sense viral derived sequences with high-sensitivity and specificity, and can be utilized to directly detect viruses from infected plant material. Furthermore, we demonstrate that the entire system can operate using only body heat and naked-eye visual analysis of outputs. We anticipate these strategies to be important components of user-friendly and deployable diagnostic systems that can be configured to detect a range of important plant pathogens.
Beyond the accounting profession
Authors: Ahn Paul D. , Jacobs Kerry 
Published: December 2018

Purpose
The purpose of this paper is to explore how an accounting association and its key members define, control, and claim their knowledge; adopt a closure and/or openness policy to enhance their status/influence; and respond to structural/institutional forces from international organisations and/or the state in a particular historical context, such as a globalised/neo-liberalised setting.

Design/methodology/approach
The authors draw on Pierre Bourdieu’s theoretical tools (field, capital, habitus, and doxa) to understand how public sector accrual accounting was defined, and how the Korean Association for Government Accounting was formed and represented as a group with public sector accounting expertise. The research context was the implementation of accrual accounting in South Korea between 1997/1998, when the Asian financial crisis broke out, and 2006/2007, when accrual accounting was enforced by legislation. The authors interviewed social actors recognised as public sector accounting experts, in addition to examining related documents such as articles in academic journals, newsletters, invitations, membership forms, newspaper articles, and curricula vitae.

Findings
The authors found that the key founders of KAGA included some public administration professors, who advocated public sector accrual accounting via civil society groups immediately after Korea applied to the International Monetary Fund for bailout loans and a new government was formed in 1997/1998. In conjunction with public servants, they defined and designed public sector accrual accounting as a measure of public sector reform and as a part of the broader government budget process, rather than as an accounting initiative. They also co-opted accounting professors and CPA-qualified accountants through their personal connections, based on shared educational backgrounds, to represent the association as a public sector accounting experts’ group.

Originality/value
These findings suggest that the study of the accounting profession cannot be restricted to a focus on professional accounting associations and that accounting knowledge can be acquired by non-accountants. Therefore, the authors argue that the relationship between accounting knowledge, institutional forms, and key actors’ strategies is rich and multifaceted.
Study on the interference between parallel pipelines and optimized operation for the cathodic protection systems
Authors: Yang Ziqing , Cui Gan , Li Zili , Liu JianGuo 
Published: December 2018

Purpose
In recent years, the demand for oil and gas pipelines has increased rapidly. Due to the restrictions of the pipeline routing, pipelines are generally laid in parallel or in the same trench, which results in stray-current interference between the independent cathodic protection (CP) systems. The purpose of this paper is to study the interference between the long-distance parallel pipelines and to obtain the optimized operation for the CP systems.

Design/methodology/approach
In this study, first, the numerical model of parallel pipelines was established using the boundary element analysis software (BEASY). Second, the effects of horizontal distance between parallel pipelines, coating damage rate, soil conductivity and anode output current on the interference of parallel pipelines were studied. Finally, by varying the layout or the output currents of CP stations, an optimized operation scheme osf long-distance parallel pipelines was put forward.

Findings
Simulation results showed that with a decrease in soil conductivity or coating damage rate, the interference increased. Moreover, the interference decreased with an increase in horizontal distance between two parallel pipelines or a decrease in anode output current. It was found that there are three methods to reduce the interference between long-distance parallel pipelines: to reduce the output currents of CP stations, combined protection and to close part of the CP stations. Among them, to close part of CP stations was the optimized scheme because of the lowest operating and maintenance cost.

Originality/value
The optimized operation scheme proposed in this study can not only solve the interference between parallel pipelines but also provide guidance for the parallel pipelines to be built in the future. Reasonably arranging the cathodic protection stations using numerical simulation can avoid the interference in the cathodic protection systems, and reduce the construction cost.