bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating Core Academic Subjects’ Learnings into Physical Education (PE): EDUball/BRAINball Approach Is Worth Exploring
Authors: Ribeiro Tiago D. , Marques Adilson , Wawrzyniak Sara 
Published: November 2024

Physical education (PE) contributes to promoting students’ cognitive development. Integrating core academic subjects into PE classes may provide numerous benefits in both cognitive and physical developments. Therefore, combining cognitive learnings of other core subjects with physical activities may increase students’ academic learning time while improving physical abilities and skills in PE classes. EDUball/BRAINball is an interdisciplinary concept that uses balls with letters and numbers to merge physical activities with various school subjects such as mathematics and languages, especially for students up to 12 years old. The pedagogical approach has been developed for over twenty years, and students who participated in it showed significant improvements in literacy, numeracy, and physical performance. Given its potential, the EDUball/BRAINball approach offers a great didactic and pedagogical alternative for teaching fundamental subjects within PE classes. This should be considered by PE teachers, who should have access and training to implement these activities in PE classes.
FROM KAISERPANORAMA TO VIRTUAL WATCH PARTIES: REDEFINING COMMUNAL VIEWING EXPERIENCE(S)
Authors: Akdag Enes 
Published: November 2024

Disclaimer: This blog post is derived from my master thesis titled “New Aspects of Communal Viewing: Subscription Video-on-Demand Platforms and Watch Parties. For further details, you can visit the link provided by Turkish Council of Higher Education Thesis Center. Although communal viewing is often associated with the moviegoing experience;
Motivation Factors of Participation in Virtual Communities of Practice: the Case of the “Educatefor.life” Community
Authors: ARZUMANYAN Lusine , WIEDER Charlotte , TESSIER Nathalie , ANGUÉ Katia 
Published: November 2024

This article explores the drivers of participation in virtual communities of practice based on Deci and Ryan’s self-determination theory (SDT). Our research is based on the study of a virtual international community. The data was collected through 14 semi-structured interviews, direct observation and analysis of documentation. The main findings confirm the importance of competence, autonomy, and relatedness as motivation factors, as in line with SDT, whereas the main contribution is the identification of energizing leader, exclusive resources, and transformative purpose as three additional motivation factors. We have also, differentiated the factors of motivation according to the level of participation in community life (core, active and periphery).
Nouveaux modes de coordinations hospitalières et de diffusion des savoirs à travers les TIC : le cas du management intermédiaire
Authors: HUSSER Jocelyn , GOUJON-BELGHIT Anne 
Published: November 2024

The research in hand deals with the dissemination of knowledge in hospitals based on the introduction and daily management of ICT by hospital middle managers. It is understood through the prism of two complementary theoretical trends, that of cognitive dissonance by Festinger (1957) and that of the use of ICT in hospital spaces (Flichy, 2003; Akrich, 2006; Grosjean and Lacoste, 2015). The results show that the production of asynchronous and hybrid organizational knowledge of the “oral-written” type is developing to the detriment of traditional interactionist knowledge with patients. Middle managers co-produce new organizational knowledge with their teams, expanded in administrative, legal and accounting matters.
Quality of life and associated factors among patients with tuberculosis at the University of Lahore Teaching Hospital, Lahore.
Authors: Zeeshan Malik  
Published: November 2024

Abstract
Methods: In 2019, cross-sectional research was carried out between April and June. a total of four hundred patients altogether were chosen. QOL was measured using the World Health Organization Quality-of-Life (WHOQOL-Bref) questionnaire. Potential predictors were examined using linear regression analysis, and variables were classified as statistically significant if their P value was below 0.05.
Results The participants had a mean age of 38.04 ± 13.53 years; the percentage of patients with pulmonary TB (PTB) was 52.71% and 57.36% were male.
Conclusion In contrast to earlier researches, this study showed that the patients' quality of life was comparatively low. Social domains were notably more affected than other domains. PTB and non-adherence indicated a negative correlation with every domain. Therefore. health care providers should stress patients' medication adherence.
Keywords Quality of life · Tuberculosis · WHOQOL-Bref · Ethiopia
Assessment of genotype by environment and yield performance of tropical maize hybrids using stability statistics and graphical biplots
Authors: Supriadi Dedy , Bimantara Yusuf Mufti , Zendrato Yuniel Melvanolo , Widaryanto Eko , Kuswanto Kuswanto , Waluyo Budi 
Published: November 2024

Background
Enhancing maize grain yield in tropical regions faces significant challenges due to variability in agroclimate, soil conditions, and agroecosystems. Understanding genotype (G) by environment (E) interaction (GEI) in plant breeding is crucial for selecting and developing high-yielding genotypes adapted to diverse environments.

Methods
Ten maize hybrids, including eight candidates and two commercial varieties, were evaluated across ten environments in Indonesia using a randomized complete block design with three replications. The GEI effect and yield stability were assessed using stability statistics, additive main effects and multiplicative interaction model (AMMI), and genotype + genotype × environment (GGE) biplot methods.

Results and Discussion
Analysis of variance revealed a significant GEI effect, indicating differences in hybrid responses for grain yield (GY), allowing for stability analysis. G01 showed the highest GY based on the best linear unbiased prediction (BLUP) across environments. Correlation analysis indicated strong associations between stability statistics (YSi and S(6)) and GY, aiding in the selection of high-yielding hybrids. The integration of AMMI with the BLUP method, and weighted average of absolute scores (WAASB), enabled precise measurement of genotype stability. Overall, G01 (R0211), G04 (R0105), G05 (R0118), and G07 (R0641) emerged as high-yielding, stable hybrids based on stability statistics, AMMI, GGE biplot, and WAASB rankings. These hybrids offer promising candidates for maize genetic improvement programs in tropical regions.
Reflection on the research on and implementation of biorefinery systems – a systematic literature review with a focus on feedstock
Authors: Wenger Julia , Stern Tobias 
Published: May 2019

AbstractTe concept of sustainably processing biomass into a spectrum of products and bioenergy is thousands of years old. Large‐scale utilization of such processes existed in the 19th century and the term biorefinery first appeared in the late 20th century. This review addresses how different feedstock classes, products, and regions have been described in the scientific literature on the development of biorefineries (1999–2017). The results of a systematic literature review were compared with information included in two reports on the implementation of biorefineries to identify similarities and differences between theory (described in the literature) and practice (carried out in industry). The number of scientific articles per year on this topic has increased over the last decade, particularly in the fields of natural sciences and engineering. The first authors of these articles are primarily affiliated with North American and European institutions. References to lignocellulosic raw materials (especially residues, but also dedicated crops) in the feedstock are by far the most frequent and those to aquatic biomass have also increased over time. Most of the products mentioned are related to energy products (mainly fuels), and the heterogeneous class of chemicals was also strongly represented. We examined two reports on existing biorefineries in Europe and identified differences between the roles of food‐crop‐based biorefineries and lignocellulosic‐feedstock biorefineries in terms of research and practice. New studies on the practical implementation of biorefineries should be carried out, with particular attention to these discrepancies. © 2019 The Authors. Biofuels, Bioproducts and Biorefining published by Society of Chemical Industry and John Wiley & Sons, Ltd.
The “Heart” of depression during early adolescence
Authors: Tu Kelly M. , Li Xiaomei , Cohen Joseph R. 
Published: May 2019

AbstractThis study examined the concurrent associations linking youths’ parasympathetic nervous system activity, specifically baseline respiratory sinus arrhythmia (RSA) and respiratory sinus arrhythmia reactivity (RSAR; vagal withdrawal), with youth depression risk in a community sample of young adolescents. Youth gender was examined as a moderator of associations. Participants included 100 youth (53% boys; M age = 11.05 years, SD = 0.33; 43% ethnic minorities), along with their mothers and teachers. Youth and mothers participated in a laboratory protocol involving a peer problem‐solving conversation, during which youths’ physiological activity was measured. Youth reported on their depressive symptoms. Teachers reported on youth depression risk via internalizing symptoms and emotion regulation (e.g., emotion lability/negativity). Results from regression analyses revealed that youths’ vagal withdrawal during the mother‐youth peer problem conversation was associated with lower youth‐reported depressive symptoms. Further, gender moderated the associations linking youth baseline RSA and RSAR with youth depression risk. Specifically, among girls but not boys, higher baseline RSA was associated with lower depressive symptoms and emotion lability/negativity, and higher RSAR (i.e., vagal withdrawal) was linked with lower internalizing symptoms. Findings contribute to the relatively small literature linking youth parasympathetic functioning with depression risk, and point to specific implications for girls.
Case of renal mucinous tubular and spindle cell carcinoma with high nuclear grade
Authors: Hatayama Tomoya , Sekino Yohei , Shikuma Hiroyuki , Mukai Sakurako , Muto Masayuki , Miyamoto Shunsuke , Sadahide Kosuke , Fukuoka Kenichiro , Fuji Shinsuke , Goto Keisuke , Shinmei Shunsuke , Hieda Keisuke , Inoue Shogo , Hayashi Tetsutaro , Teishima Jun , Kuroda Naoto , Sentani Kazuhiro , Yasui Wataru , Matsubara Akio 
Published: May 2019

IntroductionRenal mucinous tubular and spindle cell carcinoma is a rare subtype of renal cell carcinoma newly added to the World Health Organization classification in 2004. Although it has been considered as a tumor with good prognosis, aggressive cases have recently been reported.Case presentationA 52‐year‐old man was diagnosed as having left renal cell carcinoma. Open radical left nephrectomy and left‐sided pelvic lymph nodes dissection were performed. Pathological diagnosis revealed a renal mucinous tubular and spindle cell carcinoma with high nuclear grade and extra‐regional lymph nodes metastasis classified as pT3aN0M1. After nephrectomy, metastasis at second lumbar vertebra and lymph nodes recurrence were occurred.ConclusionThis tumor with high nuclear grade may be potentially aggressive and carries a poor prognosis.
Trait‐based analysis of subpolar North Atlantic phytoplankton and plastidic ciliate communities using automated flow cytometer
Authors: Fragoso Glaucia Moreira , Poulton Alex James , Pratt Nicola Jane , Johnsen Geir , Purdie Duncan Alastair 
Published: May 2019

AbstractPlankton are an extremely diverse and polyphyletic group, exhibiting a large range in morphological and physiological traits. Here, we apply automated optical techniques, provided by the pulse‐shape recording automated flow cytometer—CytoSense—to investigate trait variability of phytoplankton and plastidic ciliates in Arctic and Atlantic waters of the subpolar North Atlantic. We used the bio‐optical descriptors derived from the CytoSense (light scattering [forward and sideward] and fluorescence [red, yellow/green and orange from chlorophylla, degraded pigments, and phycobiliproteins, respectively]) and translated them into functional traits to demonstrate ecological trait variability along an environmental gradient. Cell size was the master trait varying in this study, with large photosynthetic microplankton (> 20 μm in cell diameter), including diatoms as single cells and chains, as well as plastidic ciliates found in Arctic waters, while small‐sized phytoplankton groups, such as the picoeukaryotes (< 4μm) and the cyanobacteriaSynechococcuswere dominant in Atlantic waters. Morphological traits, such as chain/colony formation and structural complexity (i.e., cellular processes, setae, and internal vacuoles), appear to favor buoyancy in highly illuminated and stratified Arctic waters. In Atlantic waters, small cell size and spherical cell shape, in addition to photo‐physiological traits, such as high internal pigmentation, offer chromatic adaptation for survival in the low nutrient and dynamic mixing waters of the Atlantic Ocean. The use of automated techniques that quantify ecological traits holds exciting new opportunities to unravel linkages between the structure and function of plankton communities and marine ecosystems.
Digital imaging evaluation of the scapula for prediction of endosteal implant placement in reconstruction of oromandibular defects with scapular free flaps
Authors: Solis Roberto N. , Mahaney Justin , Mohhebali Roxana , Laks Shaked , Wax Mark K. , Petrisor Daniel , Brockhoff Hans C. 
Published: May 2019

AbstractObjectiveDental implant placement in scapular free flaps is challenging. This study examines the scapula with computed tomography to identify ideal locations for predictable implant placement during preoperative planning.MethodsSixty‐eight adult patient chest CT scans (34 men, 34 women) captured for various medical indications, were analyzed for age, height, weight, and scapula length. The lateral border of the scapula was divided into six equal segments; the midpoints of each segment (labeled proximally to distally as 1M–6M) were analyzed in cross‐section as potential recipient sites for 3.5 × 8 mm implants. Also, we present a case of a 77‐year‐old male with ameloblastoma of the mandible who underwent patient specific planning and received a scapular free flap with dental implant placement.ResultsThere was greater bone availability in males with a mean depth of 8.3 ± 2.8 versus 5.1 ± 3.3 mm in females (p < .01). The proximal portion (1M) of the scapula in males and females had depths of 11.3 ± 1.5 and 9.5 ± 2.3 mm, respectively. Males had depths of 8.4 ± 3.0 in M3, 9.7 ± 1.7 in M4, and 8.9 ± 1.2 mm in M6. Depth of bone available for patients with heights ≥165 cm versus <165 cm had means of 10.4 ± 1.3 and 8.0 ± 1.6 mm (p < .01), respectively; but showed no significant differences between BMI (BMI <25 vs. ≥25) and bone availability (6.8 ± 1.7 vs. 6.8 ± 1.6, p = .07), or age (<55 years vs. ≥55 years) and bone availability (9.8 ± 1.6 vs. 9.8 ± 1.6, p = .11). In our case, the patient received 6 cm length of scapular bone with four 4.1 × 14 mm endosteal implants, which upon osseointegration was able to receive a fixed dental prosthesis. Three years after the initial surgery, the patient has had no difficulty with his prosthesis.ConclusionIn females the most proximal portion of the scapula will predictably accommodate a dental implant, while males have multiple sites including the proximal, middle, and distal portions.
Effect on clinical and neonatal outcomes of blastocelic microsuction prior to vitrification
Authors: Mitsuhata Shingo , Endo Yuji , Hayashi Momoko , Fujii Yoshitaka , Motoyama Hiroaki 
Published: May 2019

AbstractPurposeMicrosuction (MS) is a technique for mechanically emptying fluid from blastocele using a microneedle. In this study, we evaluated the improvement in clinical and neonatal outcomes of vitrified blastocyst transfer programs when MS of blastocelic fluid was used before vitrification.MethodsThis was a retrospective study based on data collected between March 2014 and August 2016. A total of 317 blastocysts obtained from 211 patients were analyzed. The blastocelic fluid of expanded blastocysts was aspirated completely, and blastocysts were collapsed prior to vitrification. Clinical and neonatal outcomes of warmed blastocysts were compared.ResultsThe survival rate of the MS blastocyst was significantly higher compared with the nontreatment control (98.7% vs 89.3%, OR: 9.34, 95% CI: 2.35‐36.8, P < 0.01). The rates of implantation and live birth were higher in the MS group than in the control group, but the differences were not significant. There were no differences in gestational age, birthweight, proportion of male babies, rates of cesarean section, and congenital abnormalities.ConclusionThe MS procedure improved blastocyst survival and had little effect on further embryo development after warming.
Genetic variability in parasites and host—parasite interactions
Authors: Thompson R. C. A. , Lymbery A. J. 
Published: May 2019

SUMMARYWe have examined genetic variability in parasites in the context of ecological interactions with the host. Recent research onEchinococcus, GiardiaandCryptosporidiumhas been used to illustrate: (i) the problems that parasite variability and species recognition pose for understanding the complex and often controversial relationship between parasite and host occurrence; (ii) the need for accurate parasite characterization and the application of appropriate molecular techniques to studies on parasite transmission if fundamental questions about zoonotic relationships and risk factors are to be answered; (iii) our lack of understanding about within-host interactions between genetically heterogeneous parasites at the inter-and intraspecific levels, and the significance of such interactions with respect to evolutionary considerations and the clinical outcome of parasite infections. If advances in molecular biology and mathematical ecology are to be realized, we need to give serious consideration to the development of appropriate species concepts and in vivo systems for testing the predictions and assumptions of theoretical models.
Host genetics and infectious disease
Authors: Weatherall D. J. 
Published: May 2019

SUMMARYRecent work on the inheritance of susceptibility to malaria suggests that, over what may have been a relatively short evolutionary period, a remarkably diverse series of gene families have been modified in response to the selective drive of this single infection. The phenotype consequences are not confined to the red cell, but involve the immune system, cytokines and many other systems. It seems likely that the mechanisms of variation in genetic susceptibility to other infective agents will reflect at least a similar degree of complexity and, if the selective pressures have been present for longer periods of our evolutionary history, may be even more diverse. This may have important implications for work directed at trying to define susceptibility loci for current infectious and non-infectious diseases.
Influence of host and parasite genotypes on immunological control ofTheileriaparasites
Authors: Morrison W. I. 
Published: May 2019

SUMMARYInfections withTheileria parvain the African buffalo are invariably asymptomatic, whereas infections in cattle usually result in clinical disease, the severity of which varies in different populations of cattle. The parasite exhibits antigenic heterogeneity, which in cattle manifests as differences between parasite strains in their cross-protective properties. A series of studies on T cell responses toT. parvain cattle have demonstrated that class I MHC-restricted cytotoxic T lymphocytes (CTL), specific for parasitized lymphoblasts, are important mediators of immunity. Cytotoxic T cell responses frequently display parasite strain-restricted specificities which appear to correlate with the capacity of strains to cross-protect. The strain specificity of CTL responses varies in animals immunized with the same parasite strain and is influenced by both host and parasite genotype. Recent studies have provided evidence that there is competition between epitopes for induction of CTL responses, which can result in a bias to strain-specific epitopes. These properties of the CTL response have important implications for vaccination. Thus, in designing a vaccine, it may be possible, by selecting parasite proteins containing appropriate CTL epitopes, to generate CTL responses that protect against a wide range of parasite strains. Although there are no comparable data on CTL responses in the buffalo, it is considered that the features of the immune response described for cattle would be advantageous for survival of parasite populations in the buffalo. Specifically, a bias in the immune responses to strain-specific determinants should favour establishment of infection in buffalo already carrying the parasite and allow fluctuation in the levels of different parasite strains during the course of persistent infection.
Genetic susceptibility to leishmanial infections: studies in mice and man
Authors: Blackwell J. M. 
Published: May 2019

SUMMARYTwo important recent advances inLeishmaniaimmunology are: (i) the demonstration of a dramatic dichotomy in T helper 1 versus T helper 2 subset expansion leading to protection versus disease exacerbation; and (ii) analysis of the macrophage activation pathways leading to enhanced intracellular killing of parasites, in particular the tumour necrosis factor α (TNFα)-dependent sustained induction of the inducible nitric oxide synthase gene (Nos2) leading to the generation of large amounts of nitric oxide (NO). Given the broad spectrum of disease phenotypes in human leishmaniasis, one might predict that a genetic defect at any key point in this macrophage activation pathway and/or in pathways leading to activation of different T cell subsets, and the latter may be a pleiotropic effect of the former, will contribute to disease susceptibility. By studying disease in genetically-defined inbred mouse strains, it has been possible to identify 5 regions of the murine genome carrying leishmanial susceptibility genes. The genes include: (i)Scl-2(mouse chromosme 4/human chromosome 9p; candidate Janus tyrosine kinase 1) controlling a unique no lesion growth resistance phenotype toLeishmania mexicana; (ii)Scl-1(distal mouse chromosome 11/human 17q; candidatesNos2, Sigje, MIP1α, MIP1β) controlling healing versus non-healing responses toL. major; (iii) the ‘T helper 2’ cytokine gene cluster (proximal murine chromosome 11/human 5p; candidates IL4,5,9) controlling later phases ofL. majorinfection; (iv) the major histocompatibility complex (MHC: H-2 in mouse, HLA in man: mouse chromosome 17/human 6p; candidates class II and class III including TNFα/β genes); and (v)Nramp1, the positionally cloned candidate for the murine macrophage resistance geneIty/Lsh/Bcg(mouse chromosome 1/human 2q35). This review examines these 5 regions and the candidate genes within them, reflecting on their current status as candidates for human disease susceptibility genes.