bluuebunny/crossref_metadata_2025_split huggingface dataset:
A dimensão afetiva na experiência urbana: os sentidos do habitar na cidade contemporânea/The affective dimension in urban experience: the senses of habitat in contemporary city
Authors: Mares Rizia Mendes 
Published: August 2019

No período contemporâneo, verificamos uma ênfase na difusão de imaginários urbanos, pautados em modo distintivo e fragmentário de viver a cidade tendo os muros como delimitador da sociabilidade urbana, a qual passa a realizar-se em enclaves. O que, em nosso entendimento, revela um conjunto de fatores imbuídos em uma produção prática do espaço como padrões comportamentais, relações afetivas, de valor e status social que aprofundam as desigualdades socioespaciais. Com o presente texto objetivamos refletir sobre a experiência urbana na contemporaneidade lida através das emoções e afetividade incorporadas e localizadas no contexto da vida cotidiana. Para tanto, a proposta metodológica direciona-se no sentido de tornar cognoscível as representações e simbolismos dessa experiência no espaço urbano com o uso de mapas afetivos. Uma metodologia baseada em mapas abstratos e metáforas como recursos apreensão dos afetos. O debate aqui proposto ancora-se, sobretudo, em uma revisão bibliográfica e nos indica que a experiência urbana a partir dos novos habitats, expressa a desigualdade presente na realidade brasileira e mostra-se como uma forma de enfraquecimento da experiência urbana, condição que pode ser apreensível a partir de uma metodologia que privilegie a afetividade na dinâmica socioespacial permitindo uma leitura mais subjetiva da experiência urbana.
Pengaruh Suplementasi Vitamin A pada Pengobatan Pasien TB Paru terhadap Percepatan Konversi Dahak pada Fase Intensif Di Wilayah Kerja Puskesmas Kecamatan Medan Kota
Authors: Marpaung Alexander , Siagian Parluhutan , Sari Dina Keumala 
Published: August 2019

Background: Indonesia is in the second rank for the most TB (Tuberculosis) cases in the world after India. It is estimated that there are 1 million cases per year in Indonesia.
Objective: The objective of the research was to find out the influence of Vitamin A supplementation in the medication of pulmonary TB on the acceleration of sputum conversion time at intensive phase in the Working Area of Puskesmas in Medan Kota Subdistrict.
Methods: This research applied clinical testing design with experimental approach and Experimental Quasi method. The samples were 30 newly diagnosed pulmonary TB patients consisting of15 patients in the treatment group and 15 patients in the control group. They were ³18 years old, regularly consumed category I OAT with BMI ³18.5. The statistical data were analyzed by Mann-Whitney statistical testing at reliability rate 95% (p<0.05).
Result: The results of the research on the treatment group discovered that they were mostly 18-27 years old 40.0%, male 73.3%, mostly university students 26.7%, had BTA conversion in the second week 80.0%; and the sputum conversion time was 2.4 weeks in average. The results of the research on the control group demonstrated that they were mostly 18-27 years old 33.3%, male 80.0%, mostly university students and entrepreneurs 20.0%, had BTA conversion in the second week 80%; and the sputum conversion time was 4.1 weeks in average. Vitamin A supplementation in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at intensive phase (p= <0.001) < (alpha = 0.05).
Conclusion: Vitamin A supplementation in the medication of pulmonary TB patients had some influence on the acceleration of sputum conversion at intensive phase in the Working Area of Puskesmas in Medan Kota Subdistrict
Molecular Gas toward the Gemini OB1 Molecular Cloud Complex. III. Chemical Abundance
Authors: Wang Chen , Yang Ji , Su Yang , Du Fujun , Ma Yuehui , Zhang Shaobo 
Published: August 2019

Abstract
We present analyses of the 13CO abundance

and the abundance ratio

of molecular clouds by collecting 12CO, 13CO, and C18O (1–0) transitions toward the Galactic anti-center in the ranges

and

. The

area contains eight clouds, which can be divided into two types according to

. Type I clouds, including the chain of Lynds dark clouds, West Front, Gemini OB1 giant molecular cloud (GGMC) 1, and Horn, have lower

(mean value <10) and lower column density with relatively lower temperature. Type II clouds, including GGMC 2, GGMC 3, GGMC 4, and Swallow, have a higher abundance ratio

(mean value >10) and higher column density with relatively higher temperature. For all clouds,

increases from

at the edge to

in the interior, which is probably due to an opacity effect of 12CO. In GGMC 2–4, the mean

of the molecular gas associated with H ii regions and IRAS sources is ∼14, slightly larger than that (∼9) of other subregions. This can be explained by selective far-UV photodissociation of C18O. By comparing our sample with other clouds in the plot of

against 13CO column density, we find that type I clouds are probably at an earlier evolutionary stage than type II clouds.
Stellar Metallicities and Elemental Abundance Ratios of z ∼ 1.4 Massive Quiescent Galaxies*
Authors: Kriek Mariska , Price Sedona H. , Conroy Charlie , Suess Katherine A. , Mowla Lamiya , Pasha Imad , Bezanson Rachel , Dokkum Pieter van , Barro Guillermo 
Published: August 2019

Abstract
The chemical composition of galaxies has been measured out to z ∼ 4. However, nearly all studies beyond z ∼ 0.7 are based on strong-line emission from H ii regions within star-forming galaxies. Measuring the chemical composition of distant quiescent galaxies is extremely challenging, as the required stellar absorption features are faint and shifted to near-infrared wavelengths. Here, we present ultradeep rest-frame optical spectra of five massive quiescent galaxies at z ∼ 1.4, all of which show numerous stellar absorption lines. We derive the abundance ratios [Mg/Fe] and [Fe/H] for three out of five galaxies; the remaining two galaxies have too young luminosity-weighted ages to yield robust measurements. Similar to lower-redshift findings, [Mg/Fe] appears positively correlated with stellar mass, while [Fe/H] is approximately constant with mass. These results may imply that the stellar mass–metallicity relation was already in place at z ∼ 1.4. While the [Mg/Fe]−mass relation at z ∼ 1.4 is consistent with the z < 0.7 relation, [Fe/H] at z ∼ 1.4 is ∼0.2 dex lower than at z < 0.7. With a [Mg/Fe] of

the most massive galaxy may be more α-enhanced than similar-mass galaxies at lower redshift, but the offset is less significant than the [Mg/Fe] of 0.6 previously found for a massive galaxy at z = 2.1. Nonetheless, these results combined may suggest that [Mg/Fe] in the most massive galaxies decreases over time, possibly by accreting low-mass, less α-enhanced galaxies. A larger galaxy sample is needed to confirm this scenario. Finally, the abundance ratios indicate short star formation timescales of 0.2–1.0 Gyr.
Real-world Longterm Effectiveness of Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis Patients from the Rheumatic Diseases Portuguese Register
Authors: Vieira-Sousa Elsa , Eusébio Mónica , Ávila-Ribeiro Pedro , Khmelinskii Nikita , Cruz-Machado Rita , Rocha Teresa Martins , Bernardes Miguel , Santos-Faria Daniela , Silva Joana Leite , Santos Helena , Miguel Cláudia , Carvalho Pedro , Costa Tiago , Duarte Ana Catarina , Meirinhos Tiago , Nero Patrícia , Fonseca João Eurico , Santos Maria José 
Published: August 2019

Objective.To assess longterm effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with psoriatic arthritis (PsA) registered in the Rheumatic Diseases Portuguese Register, exposed to at least 1 TNFi, prospectively followed between 2001 and 2017.Methods.Kaplan-Meier analysis was performed for first-, second-, and third-line TNFi. Responses included European League Against Rheumatism (EULAR) criteria, Disease Activity Index for Psoriatic Arthritis (DAPSA), minimal disease activity (MDA), and Ankylosing Spondylitis Disease Activity Score (ASDAS) at 3 and 6 months. Baseline predictors of discontinuation and response were studied using Cox and multivariable multinomial/logistic regression models.Results.The 750 patients with PsA showed drug retention of 4.1 ± 3.4 years (followup 5.8 ± 3.8 yrs) for first TNFi. Switching to a second (189 patients) or third (50 patients) TNFi further decreased survival by 1.1 years. Female sex, higher baseline 28-joint count Disease Activity Score, and infliximab were predictors of first TNFi discontinuation. After 6 months of the first TNFi, 48.7% of patients achieved a good EULAR criteria response and 20.9% were in DAPSA remission. There were 11.4% in MDA, and 56.4% had a good ASDAS. Responses to the second TNFi were significantly inferior compared to responses to the first TNFi. Female sex and higher baseline Health Assessment Questionnaire–Disability Index were negatively associated with good EULAR response at 3 months, and obesity decreased the chance of response at 6 months.Conclusion.In this study, switching to a second or third TNFi was associated with significantly lower drug survival and response rates for patients with axial and peripheral PsA subtypes. More successful therapeutic approaches will require considering the effect of sex and obesity on TNFi effectiveness.
Reliability and Validity of Patient-reported Outcomes Measurement Information System Short Forms in Ankylosing Spondylitis
Authors: Hwang Mark C. , Ogdie Alexis , Puravath Abin , Reveille John D. 
Published: August 2019

Objective.To assess the reliability and validity in ankylosing spondylitis (AS) of selected Patient Reported Outcomes Measurement Information System (PROMIS) Short Forms (SF) developed by the US National Institutes of Health. The analysis was done across core sets and patient-identified domains of the Assessment of Spondyloarthritis international Society.Methods.Participants in the Prospective Study of Outcomes in Ankylosing Spondylitis (PSOAS), an ongoing, prospective longitudinal observational study, completed 6 PROMIS SF assessing global health, depression, fatigue, physical function, pain intensity, and pain interference during their PSOAS visits from September 2017 to January 2019. Test-retest reliability and internal consistency were assessed using intraclass correlation coefficients and Cronbach’s alpha coefficient, respectively. PROMIS SF were compared to legacy measures collected. Construct validity was evaluated through examination of score distributions and floor effects, and through examination of the Spearman correlation coefficients between PROMIS measures and existing legacy AS measures. Discriminant validity was tested across Ankylosing Spondylitis Disease Activity Score (ASDAS) groups.Results.Participants (n = 119) were mostly male (69%), white (81%), and with a mean (SD) age of 51 (± 15) years. Legacy measures demonstrated floor effects that were not present in PROMIS SF. Good test-retest reliability (r > 0.8) and excellent internal consistency (α > 0.9) was noted in the PROMIS SF. The 6 PROMIS SF correlated moderately to strongly [ρ 0.68 (Depression) to −0.87 (Physical Function)] with appropriate legacy measures. PROMIS scores measures worsened significantly (p < 0.05) with higher ASDAS groups.Conclusion.This study supports the reliability and construct validity of PROMIS SF to assess AS symptoms from a single-center sample of patients with AS. Further research is needed to test responsiveness, feasibility/resource burden, and different cultural/societal contexts for patients with AS.
Association of Pharmacological Biomarkers with Treatment Response and Longterm Disability in Patients with Psoriatic Arthritis: Results from OUTPASS
Authors: Jani Meghna , Chinoy Hector , Barton Anne 
Published: August 2019

Objective.To identify (1) whether tumor necrosis factor inhibitor (TNFi) drug levels/anti-drug antibodies (ADAb) are associated with treatment response and disability in patients with psoriatic arthritis (PsA); and (2) the factors associated with TNFi drug levels.Methods.Patients were recruited from a national multicenter prospective cohort with longitudinal serum samples and 28-joint count Disease Activity Scores (DAS28)/Health Assessment Questionnaire (HAQ) measurement over 12 months.Results.Adalimumab (ADA) drug levels were significantly associated with ΔDAS28 (β 0.055, 95% CI 0.011–0.099; p = 0.014) and inversely with HAQ over 12 months (β −0.022, 95% CI −0.043 to −0.00063). Factors significantly associated with ADA drug levels were ADAb levels and body mass index.Conclusion.Drug level testing in ADA-initiated PsA patients may be useful in determining treatment response/disability over 12 months.
Increased Cardiovascular Risk and All-cause Death in Patients with Behçet Disease: A Korean Nationwide Population-based Dynamic Cohort Study
Authors: Ahn Hyo-Suk , Lee Dongjae , Lee Soo Young , Kim Yeong Ho , Lee Ji Hyun , Yu Dong Soo , Han Kyung-Do , Park Yong Gyu , Lee Young Bok 
Published: August 2019

Objective.Behçet disease (BD) is a chronic inflammatory multiorgan disease. An increased risk of cardiovascular disease (CVD) and heightened death rate with BD have been suggested, but to our knowledge, a nationwide large-scale study has not been conducted to date. This study aimed to determine the overall CV risk and death rate in patients with BD versus controls using the Korean National Health Insurance Service claim database.Methods.Patients with BD (n = 5576) with no previous history of CVD were selected from 2010 to 2014. An age- and sex-matched control population of individuals without BD (n = 27,880) was randomly sampled at a ratio of 5:1. Both cohorts were followed for incident CVD or all-cause death until 2015.Results.The risks of myocardial infarction (HR 1.72, 95% CI 1.01–2.73) and stroke (HR 1.65, 95% CI 1.09–2.50) were significantly higher in patients with BD than in controls. Patients with BD also had a significantly higher risk of all-cause death (HR 1.82, 95% CI 1.40–2.37) compared to controls.Conclusion.Korean patients with BD had a higher overall risk of CVD than did those without BD. Therefore, patients with BD must be carefully monitored for the potential development of CVD to ensure that appropriate early treatments are delivered.
Existe influência do nível de atividade física habitual na capacidade aeróbia e variabilidade da frequência cardíaca em mulheres na fase da pós menopausa?
Authors: Dias Wellington Gonçalves , Batista Danilo Rodrigues , Meneghel Vlademir , Ornelas Felipe De , Silva Jannes S Camargo , Braz Tiago Volpi 
Published: August 2019

O objetivo da pesquisa foi verificar se o nível de atividade física habitual (NAFH) de mulheres em fase pós menopausa apresenta influência na capacidade aeróbia e ativação parassimpática do coração em repouso. Participaram do estudo 30 mulheres na fase da pós menopausa (59,3 ± 5,3 anos; 1,58 ± 0,06 m; 64,5 ± 9,6 kg; 25,6 ± 3,1; %G = 27 ± 5%). Foram divididas em 2 grupos a partir da mediana do número de passos no pedômetro do NAFH (G1 = <NAFH, G2 = >NAFH). Foi realizado um teste incremental de caminhada progressiva (ISWT) e análise da variabilidade da frequência cardíaca (VFC) em repouso na posição supinada. Foram encontradas diferenças substanciais entre os grupos G1 e G2 para número de passos (p = 0,0001; TE = 2,55 [grande], IC 90% [0,96]; quase certeza a diferença [100/0/0%]), distância percorrida no ISWT (p = 0,0002; TE = 2,24 [grande], IC 90% [0,84]; quase certeza a diferença [100/0/0%]) e índice de ativação parassimpática da VFC (p = 0,0001; TE = 1,56 [moderado], IC 90% [0,62]; quase certeza a diferença [100/0/0%]). Conclui-se que mulheres na fase da pós menopausa com maior NAFH possuem maior capacidade aeróbia e modulação parassimpática da VFC.
A prospective randomized study comparing concurrent chemoradiation with weekly and 3 weekly cisplatin in locally advanced oropharyngeal carcinoma
Authors: Nanda R. , Katke Aradhana , Suneetha N. , Thejaswini B. , Pasha Tanvir , Jagannath K. P. , Giri G. V. , Babu Govind K. 
Published: August 2019

Abstract
Introduction: The chemotherapy schedules with cytotoxic dose or weekly regimes are still challenging, weighing the benefits versus toxicities. This prospective randomized study is an attempt to assess the efficacy of two schedules of cisplatin in management of locally advanced HNSCC. Objectives: The objectives of this study was to evaluate tolerance, tumour response and toxicities of concurrent chemoradiation with cisplatin in weekly and three weekly regimes. Methods: Locally advanced oropharyngeal squamous cell carcinoma patients fit for concurrent chemoradiation with cisplatin 40 mg/m2 (weekly) and 100 mg/m2 (3 weekly) were randomized to Arm A and B concurrently with radiotherapy of 70Gy/35frs/7 weeks. Statistical Analysis: Chi-square/Fisher Exact test has been used to find the significance of study parameters on categorical scale between the groups. The statistical software SPSS 15.0 was used. Results: Between December 2010 and January 2013, 60 patients were enrolled. The median cycles of cisplatin in Arm-A was 5 and 2 in Arm-B. The complete response of 80.9% vs 75% and partial response of 14.3% vs 12.5% was observed in both arms respectively. There was no statistical difference in acute radiation and hematological toxicities between the two groups. With median follow up of 28 months, the 2 and 5 years overall survival was 55% and 58%; 41.6% and 32.3% in arms A and B respectively. Conclusion: In our study of locally advanced oropharyngeal carcinoma treated with radical radiotherapy comparing concurrent chemotherapy with cisplatin weekly vs 3 weekly had no significant difference in overall response, complete response and acute toxicities.
Clinicopathological profile of adnexal masses presenting to a tertiary-care hospital in Bhutan
Authors: Rai Rojna , Bhutia Pema Choden , Tshomo Ugyen 
Published: August 2019

Abstract
Context: Adnexal masses of ovarian origin are of growing concern due to high fatality associated with ovarian malignancy because they are diagnosed at advanced stage due to vague symptoms and absence of recommended screening tests. Aims: The aim was to study the prevalence of histopathologic types of adnexal masses in different age groups and to analyze the accuracy of preoperative evaluation in diagnosing ovarian malignancy. Settings and Design: This was a cross-sectional study carried out in the Department of Obstetrics and Gynecology of a tertiary care hospital in Bhutan with gynecologic-oncology services, from January to December 2017. Subjects and Methods: Women presenting with adnexal mass were evaluated and those meeting criteria were enrolled. They were evaluated preoperatively with complete history, examination, ultrasound, and tumor markers. Risk of malignancy index (RMI) was calculated for all patients. Following surgery, histopathology results were compared with preoperative evaluation. Statistical Analysis Used: Chi-square test, t-test, Cohen's Kappa, and receiver operating characteristic curve analysis were used for statistical analysis. Results: Of 165 patients evaluated, 127 fulfilling criteria were enrolled. Adnexal masses of ovarian origin were most common (n = 102, 80.3%), of which 12.7% were malignant. Epithelial ovarian malignancy was the most common malignant ovarian tumor, serous cystadenocarcinoma being the most common. Malignancy was significantly more in older, postmenopausal women with high RMI. Seven out of 11 women with high RMI were diagnosed in Stage 3 or 4. RMI score at cutoff of 200 was 54.6% sensitive and 85.7% specific. Conclusions: Adnexal mass of ovarian origin was the most common. Malignancy was significantly more in older, postmenopausal women with high RMI. RMI showed moderate correlation in diagnosing epithelial ovarian malignancies.
Retinoblastoma: A retrospective analysis of 141 patients from 1983 to 2013 at a tertiary care hospital in Nagpur, India
Authors: Kabre Rohit S. , Kamble Krishna M. 
Published: August 2019

Abstract
Purpose: There is scarcity of data regarding clinical presentation and outcome of retinoblastoma patients in India. Objectives: The objective of this study was to assess the clinical profile of retinoblastoma patients in a tertiary care hospital in India from 1983 to 2013. Subjects and Methods: A retrospective analysis of clinical records of 141 patients with retinoblastoma registered from 1983 to 2013 at Government Medical College, Nagpur, India, was conducted. Demographics, clinical features, modes of treatment, and outcome of the patients were assessed. Results: Majority of patients (81 [57.45%]) presented in the age group of 1–3 years and were males. One hundred and fourteen patients (80.85%) had unilateral disease, while rare presentations of trilateral/quadrilateral retinoblastoma were also noted. Proptosis was seen in 81 (57.45%) patients as presenting symptom. Eighty-nine patients (63.12%) had locally invasive disease-involving sites. Forty-four patients (31.19%) developed distant metastasis. Surgical management and external beam radiotherapy were followed in majority of patients. Trend of increased usage of chemotherapy was seen from the mid-1990s. One hundred and twelve patients (79.43%) died with the disease. Conclusions: Data from this study show late diagnosis, leading to poor outcome for patients with advanced retinoblastoma, which is in accordance with data from other developing countries. Even though management of patients changed in accordance with changing standard of care over the decade, mortality remained high.
Performance measurement in Judo: main KPIs, cluster categorization and an ANP-based approach
Authors: Uriarte Marcos Sugoi , Rodriguez-Rodriguez Raul , Uriarte Marcos Maier , Alfaro-Saiz Juan-Jose 
Published: August 2019

<span lang="EN-US">Performance measurement in Judo usually focuses on some KPIs whose values indicate the final performance of the athlete. This paper deals with firstly identifying which these main KPIs in Judo are. Once this is done, the KPIs are classified into four different clusters: Physical training, specific training, Psychology and Lifestyle. Then, it proposes the multi-criteria decision aim technique of Analytic Network Process as the most indicate one to link not only the impact of the Judo KPIs with the achievement of the judoka’s strategic objectives but also to identify both the relative and the global importance of each of these KPIs. </span>