bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sociodemographic and clinical characteristics of juvenile delinquents
Authors: Avcil Sibelnur , Avcil Mücahit , Yılmaz Nevzat 
Published: May 2018

Purpose: In this study, it was aimed to examine the socio-demographic characteristics of the juvenile delinquents, who were sent to a university hospital by judicial authorities in order to prepare an expert report in accordance with Clause 31/2 of the Turkish Penal Code (TPC), and their families as well as nature of the offence, co morbid psychiatric diagnosis, and the prepared report results. Materials and Methods: This study was conducted by reviewing retrospectively the file records of children and adolescents who were required to be reported in accordance with Clause 31/2 of TPC in Outpatient Clinic of Child and Adolescent Psychiatry of a university hospital by judicial authorities between 01.04.2013 and 01.04.2015. From the judicial file records, socio-demographic characteristics of the cases and their families, WISC-R (Wechsler Intelligence Scale for Children-Revised) results, clinical evaluation results and information related to the judicial event were obtained. Results: It was found that 11.1% of the cases (n=7) were female and 88.9% (n=56) were male. Theft (40.5%) was on the first rank among the crime types committed by the cases who were claimed to get involved in crime. As a result of the clinical evaluation it was determined that 49.2% of the cases (n=31) had normal intelligence level, 38.1% (n=24) had borderline intelligence level, and 12.7% (n=8) had mental retardation. Conclusions: The intellectual limitations in juvenile delinquents, socio-economic difficulties, and frequency of the low education levels in both children and families are remarkable. In order to reduce juvenile delinquency, it is considered as necessary to determine the needs of children at risk and take appropriate protective and supportive measures.
Comparison of the effects of intrathecal fentanyl and intrathecal morphine on postoperative pain for inguinal hernia repair
Authors: Kılıçkaya Refika , Şahin Tuna , Güleç Ersel , Balcı Mehtap , Balcı Fatih 
Published: May 2018

Purpose: The aim of this study was to compare the effects of intrathecal fentanyl and intrathecal morphine combined with spinal anesthesia on postoperative pain control for inguinal hernia repair.Materials and Methods: Fifty patients aged 18-60 years with American Society of Anesthesiologists physical status I-II scheduled for elective inguinal hernia repair surgery were enrolled in this prospective randomized double-blinded study. Patients received spinal anesthesia with either 25 mcg fentanyl plus 12.5 mg heavy bupivacaine intrathecally (group F, n=25) or 0.1 mg morphine plus 12.5 mg heavy bupivacaine intrathecally (group M, n=25).Hemodynamic parameters, time to first analgesic requirement, postoperative pain scores, the number of analgesic requirements and side effects over postoperative 24 h were recorded.Results: Pain scores were significantly lower in group M compared with group F in the postoperative 24 h. The time to first analgesic requirement was higher in group M than group F. Analgesic requirement was higher in group F than group M for postoperative 24 h. Conclusion: We concluded that the addition of 0.1 mg morphine intrathecally to 12.5 mg heavy bupivacaine provides improved postoperative analgesia, especially after postoperative 12 h than 25 mcg fentanyl for inguinal hernia repair under spinal anesthesia.
Histopathological subtypes of pediatric lymphomas and relation to Ebstein-Barr virus: an immunohistochemical and in situ hybridization study
Authors: KILIÇ BAĞIR Emine , AÇIKALIN Arbil , ERGİN Melek , SEZGİN Gülay , KÜPELİ Serhan , SEYDAOĞLU Gülşah 
Published: May 2018

Aim: Lymphomas are the second most common malignant disease after leukemia
and brain tumors in developing
contries. Ebstein-Barr virus has a
initiator role in the development of lymphoma,
but it is known that socioeconomic conditions, genetic features and the immune
supressive factors is also important. We aimed to explore the histopathologic
subtypes of pediatric lymphomas and their relation with Ebstein-Barr virüs infection
in our region.Material
and Methods: In this
retrospective study, 87 children
including 36 cases with hodgkin lymphoma and 51 cases with non-hodgkin lymphoma
were included in the study. The pathologic slides were used to investigate immunohistochemical staining with Ebstein-Barr
virüs latent membrane protein-1 and in-situ hybridization.
Results: The most common histopathological subtype in hodgkin lymphoma cases were mixed cellular classical Hodgkin lymphoma
(55.6%) followed by nodular sclerosis classical hodgkin lymphoma (16.6%). The most common histopathological subtype in non-Hodgkin
lymphoma cases was Burkitt lymphoma
(51.0%) followed by precursor T-cell lymphoblastic leukemia/lymphoma (13.7%). Ebstein-Barr
virüs latent membrane protein-1 was positive in 29 Hodgkin lymphoma. All non-Hodgkin lymphoma cases were
stained negative with ımmunohistochemical. The positive staining rate of Hodgkin lymphoma cases with in-situ hybridization
was 83.3% and this rate was
27.5% in non-Hodgkin lymphoma cases. The differences between groups for both
staining methods were statistically significant (p&lt;0.001)

Conclusion: The results of this study show that the distribution of histopatholojik
subtypes of pediatric lymphomas similar to in developing countries. And we have
observed that in-situ hybridization is
more specific than immunohistochemistry because Ebstein-Barr virus positivity is more detected in in-situ hybridization.
Cardiac effects of hemodialysis in children with chronic kidney disease
Authors: Arslan Alev , Küçükosmanoğlu Osman , Noyan Zekiye Aytül , Özbarlas Nazan 
Published: May 2018

Purpose: The aim of the study was to evaluate cardiac functions before and after hemodialysis in children with chronical renal failure.Materials and Methods: The study comprised 24 children undergoing hemodialysis more then six months. Conventional and tissue Doppler echocardiography was performed, NT-proBNP levels were measured before and after hemodialysis. Echocardiographic results were compared regard to hydration status which measured with body composition monitor and hypotension event during dialysis. Results: Myocardial performance indices which gained with tissue Doppler echo were high in 22 patient. Mitral E/A ratio significantly decreased after hemodialysis. NT-proBNP levels were high but no difference was determined after dialysis. Nine patient experienced hypotension but nonsignificant difference was detected regarding echocardiographic findings and NT-proBNP levels. Conclusion: Diastolic dysfunction is frequent in chronical renal failure. Tissue Doppler echocardiography and myocardial performance index supply a more proper evaluation of global and regional cardiac function in chronical renal failure due to less hydration affectability. NT-proBNP should be monitored for cardiac dysfunction in chronical renal failure. Body composition monitor should be used in children for setting the ultrafiltration volume.
Cancerous cell lines alter their genomic organization and karyotype with increased passage number: a cytogenetic study
Authors: YILMAZ M. Bertan , TUNÇ Erdal , ILGAZ N. Seda , ÖKSÜZ Hale , ÖZTECİK Ezgi , ÖZPAK Lütfiye , ÖCAL İşıl , PAZARBAŞI Ayfer , DEMİRHAN Osman 
Published: May 2018

Purpose: The limited use of mammals in human health related scientific research has led to the development of new research strategies like cell culture techniques. Commercially available cancerous cell lines that are well characterized by cytogenetics and biochemical markers allow comparison of results among different laboratories. However, as these cell lines tend to be maintained in culture over long periods of time, mutations can occur that may change characteristics and responses of cell lines that have initially been identified or non-existed at earlier passages. Here we cytogenetically investigated the chromosomal rearrangements in repeated cultures of six different cell lines over continuous passages. Method: MCF7, HCT116, A549, SHSY5Y, HEPG2, and NIH3T3 cell lines were cultured in DMEM containing 10% FBS and 1% penicillin-streptomycin. GTG banding procedure was used for the analysis of metaphase chromosomes, at least 20 metaphases were analyzed per cell line. Results: We found chromosome number variations and structural changes in the all examined cell cultures as the passage numbers increase. Conclusion: Cell lines have long been used in research to test drugs, to delineate molecular mechanisms, to understand the environmental effects and so on. The most important feature of a cell line is its genotype and karyotype similarities with their host organism. Cancer Cell lines, possess genomic/chromosomal instability that also lead them to change their phenotype along with their karyotype from one passage to next. Therefore, it is always best to verify karyotype before employing a specific cell line in a research project.
Effectiveness of Bobath therapy on balance in cerebral palsy
Authors: Kavlak Erdoğan , Ünal Ayşe , Tekin Fatih , Altuğ Filiz 
Published: May 2018

Purpose: Weakness on balance control is one of the most common problems for children with cerebral palsy. Present study aimed to investigate the effectiveness of 8 week-Bobath therapy on balance in children with diparetic or hemiparetic cerebral palsy.Materials and Methods: A total of 15 cerebral palsy diagnosed children (8 diparesis, 7 hemiparesis) aged 5-14 years, were included in this study. Children could walk independently or by using a walking aid. The demographic data were saved for each case. Gross Motor Function Classification System and Gross Motor Function Measure were used to determine level of motor function. 1 Minute Walking Test, 10-meter Walking Test, Pediatric Balance Scale for balance ability and Functional Independence Measure for children (WeeFIM) for assessing of independence in activities of daily living were used. Bobath therapy were applied to children one 60-minute session, 2 days a week and 8 weeks in total. All evaluations were performed before treatment and repeated after treatment program.Results: After 8-week Bobath therapy, the results showed that improvement in motor function, level of functional independence and balance scores were statistically significant. Conclusion: Bobath therapy improves functional motor ability, independence level on daily living activities, and also balance ability in children with cerebral palsy.
Effects of dentin graft on bone mineral density of newly formed bone: an experimental animal study
Authors: MERCAN Uğur , SÜMER Mahmut , UÇAK SEMİRGEN Sibel , BALLI Umut , BETİL KABAK Yonca , ŞENYURT Özgün 
Published: May 2018

Purpose: The aim of this study was to evaluate the bone mineral density of dentin used as bone graft material in bone defects. Materials and Methods: Sixteen male New Zealand white rabbits were used. Two critical-size calvarial bone defects were created in each rabbit and filled with different types of grafts. The bone defects were divided into four groups. The defects in group A1 were filled with processed dentin from human teeth; group A2 was filled with processed dentin from rabbit teeth; group B1 was filled with bovine bone (Bio-Oss), and the defects in group B2 were left empty. Bone mineral density was evaluated using dual-energy X-ray absorptiometry at the 4th and 12th weeks. Results: The bone mineral density values at the 4th week were not statistically different among groups A1, A2 and B1. However, the bone mineral density values at the 12th weeks were significantly higher for group B1 than the other groups. Histopathologic evaluations showed better bone-healing for group B1 than group A1 and A2. Conclusion: Dentin grafts and bovine bone graft have similar outcomes according to the bone mineral density values at the early term of bone-healing (4 weeks). However, in the late term of bone-healing (12 weeks), bone mineral density values of bovine bone were better than the other groups.
Relationship between pulmonary and cognitive functions in myotonic dystrophy type 1: a preliminary study
Authors: Evlice Ahmet , Kuleci Sedat , Koç Filiz 
Published: May 2018

Purpose: We aim to evaluate the correlation of neurocognitive findings with pulmonary functions in Myotonic dystrophy type 1 (DM1).Materials and Methods: This is an observational prospective (between 2013-2015 years) cross-sectional single center study at Neurology and Chest clinics of Cukurova University. Mini mental state examination, forward and backward digit span, verbal fluency (semantic and lexical), clock drawing, verbal and visual memory, pulmonar function tests, arterial blood gas samples were performed to DM1 patients and control group. The presence of correlation between neurocognitive tests and pulmonary function, arterial blood gas samples were researched in DM1. Results: There were significant differences between DM1 (10 male, 14 female) and control group (12 male, 9 female) on verbal fluency, clock drawing, forward and backward digit span tests. There was a positive correlation (p&amp;lt;0.05) between verbal fluency and respiratory function tests (total lung capacity) in DM1.Conclusion: In the present study; we encountered a positive correlation between total lung capacity and verbal fluency in DM1. Pulmonary function tests and neurocognitive assessment should be performed concomitantly in DM1 patients. This provides early detection and treatment of cognitive impairment and loss of pulmonary functions.
Kalıcı tünelli hemodiyaliz kateterlerinin etkinliği ve uzun dönem sonuçları
Authors: ARPACI Taner , ÖZER Caner , YILDIZ Altan 
Published: May 2018

Amaç: Bu çalışmada son dönem böbrek yetmezliği hastalarına takılan tünelli kalıcı hemodiyaliz kateterlerinin uzun dönem etkinliğinin ve kateter disfonksiyonuna yol açan komplikasyonların değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Son dönem böbrek yetmezliği tanılı 40 hastaya iki yıllık çalışma süresinde ultrasonografi ve floroskopi eşliğinde toplam 68 adet kalıcı hemodiyaliz kateteri takıldı. Erken ve geç dönemde ortaya çıkan komplikasyonlar retrospektif olarak değerlendirildi. Ortalama primer, sekonder ve total kateter ömürleri hesaplandı.Bulgular: Yaşları 20 ile 80 arasında (ortalama 58,2) değişen 40 hastanın 28'i kadın (%70), 12'si erkekti (%30). Uzun dönem komplikasyonlar toplam 58 kez saptandı (1000 kateter gününde 5.2 kez). Kateter trombozu, 10 hastada toplam 28 kez (2.5/1000 kateter günü), kateter bağımlı sepsis 14 hastada toplam 14 kez (1.25/1000 kateter günü), kateterin spontan yerinden çıkması 3 hastada toplam 3 kez (0.27/1000 kateter günü), kateter giriş yerinden kanama 6 hastada toplam 7 kez (0.63/1000 kateter günü), yetersiz kan akımı 3 hastada toplam 3 kez (0.27/1000 kateter günü) saptandı. Buna göre ortalama primer kateter ömrü 186 gün, sekonder kateter ömrü 133 gün ve genel kateter ömrü 164 gün olarak hesaplandı. Sonuç: Kronik hemodiyalizde nativ arteriovenöz (AV) fistül günümüzde en ideal vasküler girişim yoludur. Çeşitli nedenlerle AV fistül kullanamayan hastalarda tünelli kalıcı hemodiyaliz kateterleri iyi bir alternatiftir.
Şizofreni hastalarında fiziksel hastalık eş tanılarının değerlendirilmesi
Authors: Demirel Döngel Betül , Demirkol Mehmet Emin , Tamam Lut 
Published: May 2018

Amaç: Bu çalışmada şizofreni
hastalarının fiziksel hastalık eş tanı profillerinin çıkarılması amaçlanmıştır.
Fiziksel hastalıkların sosyodemografik verilere ve klinik özelliklere göre
farklılıklar gösterip göstermediğinin tanımlanması planlanmıştır.

Gereç ve Yöntem: Çalışmaya Çukurova
Üniversitesi Tıp Fakültesi Balcalı Hastanesi Ruh Sağlığı ve Hastalıkları
Anabilim Dalı’nda ve Adana Doktor Ekrem Tok Ruh Sağlığı ve Hastalıkları
Hastanesi’nde tedavi görmekte olan şizofreni hastaları alındı. Görüşmeler tek
bir görüşmeci tarafından 30-45 dakikada gerçekleştirildi. Görüşme sırasında
sosyodemografik veri formu, fiziksel hastalıklar listesi ve mevcut fiziksel
hastalık listesi görüşmeci tarafından dolduruldu.

Bulgular: Çalışmamıza 537 hasta
katılmıştır. Hastaların 219'u (%40,8) kadın, 318'i (%59,2) erkektir. Hastaların
yaş ortalaması 38,50 ±12,21'dir. Hastaların 495'inde (%92,2) herhangi bir fiziksel
hastalık olduğu saptanmıştır. Bu hastalıklardan en sık görüleni 458 (%85,3)
hastayla ağız-diş sağlığı problemleridir. Daha sonra ise obezite gelmektedir
(170 hasta, %31,7). 3. sıklıkta gözlenen hastalık diyabet olup 50 (%9,3)
hastada bulunmuştur. Ardından ise hipertansiyon ve hiperlipidemi gelmektedir
(her ikisi de 39 hastada saptanmıştır, %7,3).

Sonuç: Elde ettiğimiz bulgular
şizofreni hastalarının büyük çoğunluğunun bir fiziksel hastalık eş tanısı
olduğunu göstermiştir. Şizofreni hastalarının genel tıbbi durumu ilgilendiren
hastalıklarına karşı özenli olmamaları nedeniyle bir kısım hastalıklarının
tanısının atlandığı da düşünülünce bu oranların çok daha yüksek olduğu sonucuna
varılabilir. Bazı hastalıkların sıklıklarının şizofreni hastalarında arttığına
da dikkat edilirse şizofreni hastalarının en önemli ölüm sebeplerinden olan fiziksel
hastalık eş tanılarının etkin şekilde tanılanması ve tedavi edilmesi
gerekliliği kanaatine varılmıştır.
Negative effects of polygamy on family members in the province of Diyarbakir, Turkey
Authors: Okan İbiloğlu Aslıhan , Atlı Abdullah , Özkan Mustafa 
Published: May 2018

Purpose: We aimed to here, determine whether the different sociodemographic and clinical variables of polygamous and monogamous marriages.Materials and Methods: 104 polygamous husbands with 56 monogamous husbands from Diyarbakir which located in southeastern region of Turkey, were face to face interviewed, by the researchers. Complaints of all participants were assessed through the SCL-90-R test.Results: Our findings show that about 75% of the husbands were pleased to in polygamous marriages. There was significantly differences between senior wives and junior wives’ ages, in polygamous marriage. Polygamous husbands' GSI subscore, in SCL-90-R, along with their psychoticism, hostility and phobic anxiety's sub-scores were significantly higher than scores of monogamous husbands. Conclusion: A growing number of studies show that, polygamous marriage is associated with depressive and anxiety disorders, somatization disorders and a loss of self-esteem. In addition to, having the responsibility of supporting “multiple women and children”, men can have different problems in a polygamous marriage. It should be noted that, polygamy is a complex phenomenon with deep cultural, social, economic, and political roots that has been associated with child’s, husband’s and wive’s mental health symptoms. Our results, polygamous marriages are associated with higher risk for psychiatric disorders among the all family members, regardless of their education, family socioeconomic profiles and household composition as well as these results highlighted important implications for clinical practices and future researches.
Arka kapsül bütünlüğü olmayan olgularda arka kamara göz içi mercek implantasyonu
Authors: Şingar Özdemir Evin , Altıparmak Uğur Emrah , Ünlü Nurten , Özdemir Yaprak Arzu , Duman Sunay 
Published: May 2018

Amaç: Bu çalışmanın amacı yeterli arka kapsüler desteği olmayan hastalarda primer iris-fiksasyonlu ve skleral fiksasyonlu arka kamara göz içi mercek implantasyonlarının sonuçlarını karşılaştırmaktır.Gereç ve Yöntem: Katarakt ameliyatı sırasında yetersiz arka kapsül desteği nedeniyle primer sütüre arka kamara göz içi mercek implantasyonu yapılan hastaların prospektif analizi yapıldı. En iyi düzeltilmiş görme keskinliği, görme keskinliği artışı ve gelişen komplikasyonlar değerlendirildi.Bulgular: Çalışmamızda 13 hastaya (%30,2) iris-fiksasyonlu ve 30 hastaya (% 69,8) skleral fiksasyonlu arka kamara göz içi mercek implantasyonu uygulandı. İris fiksasyonlu grupta 11 hastada (%84,6), skleral fiksasyonlu grupta 25 hastada (%83,3) görme keskinliği , Snellen eşeline göre en az 1 sıra arttı. İris fiksasyonlu grupta % 30,8 hastada (n = 4), skleral fiksasyonlu grupta % 50 hastada (n = 15) 0,5 ve üzerinde en iyi düzeltilmiş görme keskinliği mevcuttu. Sonuç: Primer iris-fiksasyonlu ve skleral fiksasyonlu arka kamara göz içi mercek implantasyonları tatmin edici görsel sonuçlar vermektedir. Sütüre arka kamara göz içi merceğin fikse edileceği bölgenin seçiminde altı çizilmesi gereken noktalar; gözünün ameliyat öncesi durumu, arka kamara göz içi merceğin fikse edilecek bölgenin durumu, lensin türü ve cerrahın tercihidir.
Relationship between the patients’ sense of security and the gap in the quality of services in hospitals of Sari city, Iran
Authors: Rostami Farideh , Nadi Aliasghar , Abedi Ghasem , Moosazadeh Mohammad , Abedini Ehsan , Khosravi Shadmani Fatemeh , Mansori Kamyar 
Published: May 2018

Purpose: This study aimed to investigate the relationship between the patients’ sense of security and the gap in the quality of services in the selected hospitals in the year 2015.Materials and Methods: The present study, as applied research, followed a descriptive-analytical approach. The sample used in this study comprised 600 patients, hospitalized in Imam and Shafa Hospitals in Sari, in addition to ValiAsr Hospital in Ghaemshahr, with at least 24 hours in internal, surgery, women, and children wards. The data were initially collected through the standard SERVQUAL questionnaire with two sections of demographic and specific questions including 22 five-point Likert scale questions, and one other 76 five-point liker scale questions regarding the sense of security among the patients. Results: The results of the study showed that the mean, median, and mode values of the gap (the distance between perceptions and expectations) equaled -0.61, 0.59, -0.55, respectively, with the Standard Deviation of 0.46. Through examining the relationship between gap and sense of security, it was observed that Spearman correlation coefficient was 0.289, which showed a significant relationship between the two elements.Conclusion: Given the direct relationship between the gap in services and the patients’ sense of security, it is essential that specific opportunities to be provided for the hospitals to improve their service quality.
Laparotomi uygulanan künt karın travmalı hastalarda prognostik faktörler ve travma skorlama sistemlerinin prognostik değeri
Authors: Ülkü Abdullah 
Published: May 2018

Amaç: Bu çalışmanın amacı, laparotomi uygulanan künt karın travmalı olgularda prognozu etkileyen faktörleri ve travma puanlama sistemlerinin prognostik değerini saptamaktır.Gereç ve Yöntem: 1 Ocak 1998 ile 31 Aralık 2005 tarihleri arasında laparotomi uygulanan 151 künt karın travmalı olgu retrospektif olarak incelendi. Travma ve Yaralanma Şiddet Puanı (TYŞP), APACHE II, Yaralanma Şiddet puanı (YŞP), Düzeltilmiş travma puanı (DTP), Travma puanı (TP), Circulation , Respiration , Abdomen , Motorn and Speech (CRAMS) ve Glasgow koma ölçütü için tüm hastaların travma skorları hesaplanarak hasta sonlanımları açısından karşılaştırıldı.Bulgular: En sık travma şekli trafik kazaları (%73.4), en sık yaralanan organ dalaktı (%36.5). Hastaların 54 (%34.8)’ünde postoperatif major cerrahi komplikasyon gelişti ve 37 (%24.5) hasta öldü. Hasta sonlanımlarını tahminde Travma ve Yaralanma Şiddet Puanı, APACHE II, Yaralanma Şiddet puanı, Düzeltilmiş travma puanı, Travma puanı, CRAMS ve Glasgow koma ölçütünün doğruluk oranları sırasıyla %92, %87, %80, %72, %69, %68 ve %66 olarak bulundu. Sonuç: Laparotomi uygulanan künt karın travmalı hastalarda Travma ve yaralanma Şiddet puanı ve APACHE II hasta sonlanımını tahminde en iyi sistemler olarak bulunurken 55 üzeri yaş, 6 üniteden fazla kan tranfüzyonu, travma ile operasyon arasındaki sürenin 12 saatten uzun olması ve postoperatif komplikasyon gelişimi bağımsız prognostik faktörler olarak saptandı.