bluuebunny/crossref_metadata_2025_split huggingface dataset:
18F-FET and 18F-FCH uptake in human glioblastoma T98G cell lines
Authors: Persico Marco Giovanni , Buroni Federica Eleonora , Pasi Francesca , Lodola Lorenzo , Aprile Carlo , Nano Rosanna , Hodolic Marina 
Published: April 2018

Abstract

Background
Despite complex treatment of surgery, radiotherapy and chemotherapy, high grade gliomas often recur. Differentiation between post-treatment changes and recurrence is difficult. 18F-methyl-choline (18F-FCH) is frequently used in staging and detection of recurrent prostate cancer disease as well as some brain tumours; however accumulation in inflammatory tissue limits its specificity. The 18F-ethyl-tyrosine (18F-FET) shows a specific uptake in malignant cells, resulting from increased expression of amino acid transporters or diffusing through the disrupted blood-brain barrier. 18F-FET exhibits lower uptake in machrophages and other inflammatory cells. Aim of this study was to evaluate 18F-FCH and 18F-FET uptake by human glioblastoma T98G cells.

Material and methods
Human glioblastoma T98G or human dermal fibroblasts cells, seeded at a density to obtain 2 × 105 cells per flask when radioactive tracers were administered, grew adherent to the plastic surface at 37°C in 5% CO2 in complete medium. Equimolar amounts of radiopharmaceuticals were added to cells for different incubation times (20 to 120 minutes) for 18F-FCH and 18F-FET respectively. The cellular radiotracer uptake was determined with a gamma counter. All experiments were carried out in duplicate and repeated three times. The uptake measurements are expressed as the percentage of the administered dose of tracer per 2 × 105 cells. Data (expressed as mean values of % uptake of radiopharmaceuticals) were compared using parametric or non-parametric tests as appropriate. Differences were regarded as statistically significant when p<0.05.

Results
A significant uptake of 18F-FCH was seen in T98G cells at 60, 90 and 120 minutes. The percentage uptake of 18F-FET in comparison to 18F-FCH was lower by a factor of more than 3, with different kinetic curves.18F-FET showed a more rapid initial uptake up to 40 minutes and 18F-FCH showed a progressive rise reaching a maximum after 90 minutes.

Conclusions

18F-FCH and 18F-FET are candidates for neuro-oncological PET imaging. 18F-FET could be the most useful oncological PET marker in the presence of reparative changes after therapy, where the higher affinity of 18F-FCH to inflammatory cells makes it more difficult to discriminate between tumour persistence and non-neoplastic changes. Additional studies on the influence of inflammatory tissue and radionecrotic cellular components on radiopharmaceutical uptake are necessary.
Preceitos para bem viver: um estudo sobre manuais de civilidade e etiqueta na década de 1950
Authors: Cunha Maria Teresa Santos , Santos Márcia Regina 
Published: April 2018

O período posterior às guerras mundiais demandou a reinvenção das convivências, do sentimento de pertença e das formas de distinção. O presente artigo discutirá as leituras de formação, mais precisamente, manuais de etiqueta e boas maneiras produzidos para contribuirem no processo de reabilitação dos modos compreendidos como civilizados, no sentido de compreender as concepções do que é civilizado em cada tempo, as formas mobilizadas para internalizar os hábitos, os tipos de conteúdos divulgados e quais eram os ensinamentos propostos na literatura sobre boas maneiras.. Como corpo documental foram selecionados dois manuais de boas maneiras produzidos na década de 1950, editados e comercializados no Brasil, intitulados Aprenda boas maneiras, da autora Dora Maria (1958) e Boas maneiras, da autora Carmen D’Ávila (1958). A análise dos documentos sinalizou que a formação proposta nos dois manuais se constrói a partir de lugares diferentes que convergem para uma mesma organização. As considerações elaboradas a partir da discussão com as propostas por Norbert Elias sobre o tema, a abordagem de alguns conteúdos e a análise da materialidade permitiram evidenciar a continuidade dessa demanda por formação e o potencial de alcance das prescrições.
Direito Fundamental a uma nacionalidade
Authors: Cavallieri Leila Arruda 
Published: April 2018

Os direitos fundamentais são a base da garantia do exercício pleno da dignidade humana.A salvaguarda desses direitos pelo país é um dever que não pode ser relegado ou olvidado. Desta forma, existem mecanismos que compelem o Estado a proteger, defender e cobrar respeito pelos mesmospor parte da sociedade e de outros Estados. No caso da adoção internacional, o direito à convivência familiar é conquistado pelos adotandos a partir da sentença judicial brasileira. Porém, ao se tornarem filhos de pais domiciliados em outro Estado, as crianças e adolescentes aqui nascidos precisam ter as garantias que são atinentes ao status de cidadão daquele país. A partir do reconhecimento do direito à nacionalidade pelo país de acolhida das crianças, elas passam a usufruir de uma condição de equiparação a seus adotantes, do ponto de vista de direitos e deveres. A nacionalidade ou cidadania para os adotandos é um direito fundamental que necessita ser conquistado e preservado, através das normativas internas ou de direito convencional, visando atender ao superior interesse da criança ou adolescente. A legislação italiana é uma das legislações estrangeiras que possui tais dispositivos, o que se torna uma grande conquista no direito transnacional. PALAVRAS-CHAVE: direitos fundamentais; adoção internacional; direito à convivência familiar; direito à nacionalidade Abstract Fundamental rights are the basis for ensuring the full exercise of human dignity. The safeguarding of these rights by the country is a duty that can not be relegated or forgotten. Thus, there are mechanisms that compel the State to protect, defend and claim respect for them by society and other States. In the case of international adoption, the right to family coexistence is won by adoptees based on the Brazilian judicial decision. However, when they become children of parents domiciled in another State, the children and adolescents here born need to have the guarantees that are pertinent to the status of citizen of that country. From the recognition of the right to nationality by the host country of the children, they will enjoy a condition of equality with their adopters, from the point of view of rights and duties. Nationality or citizenship for adopte is a fundamental right that needs to be won and preserved, through internal norms or conventional law, in order to meet the superior interest of the child or adolescent. The Italian legislation is one of the foreign laws that have such devices, which becomes a great achievement in transnational law. KEYWORDS: fundamental rights; international adoption; right to family life; right to nationality
Effect of Bio-Control Agents on Yield, Yield Components and Root Rot Control in two Wheat Cultivars at New Valley Region
Authors: MOUBARK Mohamed Yosseif , ABDEL-MONAIM Montaser Fawzy 
Published: April 2018

This study evaluated the effectiveness of applying the bioagents Bacillus subtilis (isolate BSM1), B. megaterium (isolate BMM5), Trichoderma viride (isolate TVM2) and T. harzianum (isolate THM4) for the control of rot root disease caused by Fusarium graminearum, Drechslera halodes and Rhizoctonia solani on two wheat cultivars ('Sakha 93' and 'Bani Suif 5') under greenhouse conditions. Moreover, their effect wheat growth and yield were also studied under field conditions. In vitro, all tested bioagents were significantly in the reduced redial growth of the pathogenic fungi. Trichoderma viride was active more than the other tested bioagents followed by T. harzianum, while B. subtilis was the least ones. Under greenhouse conditions, all tested bioagents were able to reduce significantly damping-off and root rot caused by the tested pathogens compared with control and increased fresh and dry weight of the survival plants when applied as soil or grain treatments however, there was variation among bioagent isolates effect on reduction of disease severity both application methods. Trichoderma viride and B. megaterium were recorded the highest effective in this respect compared with other tested bioagents. Under field conditions, analysis of variance and mean performance were estimated for four characters: grain yield 4.8 m-2, No. of spikes m-2, No. of kernels spike-1 and 1,000-kernel weight. Significant mean squares were obtained for all studied characters between the seasons (S), methods (M), (S) (M), treatments (T), (S) (T), (M) (T) and (S) (M) (T) for 'Sakha 93' cultivar and 'Bani Suif 5' cultivar except application methods and (S) (M) for number of kernels spike-1 and 1,000-kernel weight, respectively. While the treatments T. harzianum and B. megaterium were the best treatments to increase grain yield, the treatments B. subtilis and T. harzianum were best treatments to increase number of spikes and the treatments B. subtilis and B. megaterium were best treatments to increase number of kernels for soil and grain application methods, respectively.
Plant Spacing and Cultivar Affects Yield Components, Qualitative Traits and Early Ripening of Tomato (<i>Lycopersicon esculentum</i>)
Authors: MAMNOIE Ebrahim , DOLATKHAHI Ali 
Published: April 2018

Two-year field trial was set up on sandy clay soil in the Jiroft and Kahnouj Agricultural Research Center with the objective to determine the effect of plant spacing and different cultivars on the yield and qualitative characteristics of tomato (Lycopersicon esculentum). This experiment was performed as split plot based on complete randomized block design with 3 replications. The main plots were in – row
spacing in 4 levels include 0.3, 0.4, 0.5 and 0.6 m and the subplots were cultivars naming ‘Shef ’, ‘Peto Early CH’ and ‘FDT 202’. The results showed that, fruit length to diameter ratio, total acidity, fruit number per plant, mean fruit weight, yield per plant, total yield and first harvest to total harvests ratio were significantly affected by plant spacing. In addition, cultivars showed significant effect on all traits evaluated (p
Prevalence of intestinal parasitic infections in cases of diarrhoea among school children attending a tertiary care hospital: a two year study
Authors: Tenali Ravi Kumar , Badri Naveen Kumar , Kandati Jithendra , Ponugoti Munilakshmi 
Published: April 2018

Background: Globally every year 1.7 billion cases of diarrhoea are registered as per the WHO report 2017. Intestinal parasitic infections [IPI] are one of the top ten major public health problems in developing countries with an estimated prevalence of 30-60% in developing countries compared to 3% in developed countries. School age children are the common vulnerable group with the highest prevalence and infection intensities. The objective of the present study is to study the prevalence of parasitic infections in school children as a causative factor for diarrhoea and associated risk factors involved with relation to their hygiene and socio demographic characters.Methods: A cross sectional study was conducted for a period of two years from January 2015 to December 2016 and stool specimens from the children aged 5-18 years suffering from diarrhoea were screened for parasitic infections following standard guidelines and as per the ethical committee guidelines. The socio demographic characters, risk factors and hygienic characters of the cases were noted from the parents or guardians or children in a separate predesigned questionnaire sheet. Data was analyzed using SPSS software version 13 and P value<0.05 was considered significant.Results: T The prevalence of parasitic infections in the Present study was 22.95% and males were more common. 8-11 years was the most common age group and mean age was 11.6±1.8 years. Statistically significant association was found with hand washing before meals, socio economic status, and method of hand washing after defecation. Entamoeba histolytica was the major parasitic pathogen followed by Ascaris lumbricoides. Other parasites were Giardia lamblia, Ancylostoma duodenale, Cryptosporidium, Isospora, Enterobius and Trichuris trichura. Conclusions: There is lack of awareness regarding dog bite and its management among the rural population.
Prone ventilation: does it have a role in neonates
Authors: Taneja Sunil , Agarwal Neha , Tandon Ayank 
Published: April 2018

In patients of various ages undergoing mechanical ventilation, it has been observed that positions other than the standard supine position, such as the prone position, may improve respiratory parameters and outcome. The benefits of these positions have not been clearly defined for critically ill newborns receiving mechanical ventilation.
ESTRATO REGENERANTE DO COMPONENTE LENHOSO EM ÁREA DE CAATINGA COM DIFERENTES USOS, NO SERIDÓ POTIGUAR
Authors: Lucena Marcelo Silva de , Silva Josuel Arcanjo da , Alves Allyson Rocha 
Published: April 2018

Este trabalho objetivou avaliar o comportamento da regeneração do estrato lenhoso da vegetação de Caatinga sob duas formas de usos, em duas áreas contíguas. A primeira está localizada na Estação Ecológica do Seridó (EES); a outra na Fazenda Pedro Cândido (FPC); as duas situadas em Serra Negra do Norte-RN. Foram incluídos indivíduos com CAP (circunferência do caule à altura de 1,3 m a partir do solo) ≤ 6 cm e altura mínima > 0,5 m. Estes foram distribuídos em duas classes de tamanho de regeneração natural (CTRN), a partir das quais se estimou as classes absoluta e relativa de tamanho e calculado o parâmetro regeneração natural relativa. Na EES, as espécies mais importantes para regeneração foram Croton blanchetianus (Pohl) Baill., Erythroxylum pungen O.E.Schulzs e Poincianella pyramidalis (Tul.) L. P. Queiroz. Na FPC, foram Croton blanchetianus e Aspidosperma pyrifolium Mart. As espécies dominantes tanto na EES quanto na FPC mantêm esse status em função da grande densidade de indivíduos nas áreas circundantes, de suas características pioneiras e dos diferentes usos das áreas. A menor intensidade de antropismo favoreceu a regeneração de uma comunidade mais diversificada e com menor dominância.
Message from Editor
Authors: Uzunboylu Prof. Dr. Huseyin 
Published: April 2018

Message from Editor

Dear Colleagues;

It is a great honour for us to welcome you as Editor of Cypriot Journal of Educational Sciences, which has accepted publications indexed in qualified databases since 2006. Our main aim is to increase the quality of the journal day by day. We are ready to publish the new issue of Cypriot Journal of Educational Sciences, which has eight articles with authors from various countries. The aim of this issue is to give the researchers an opportunity to share their academic studies.

First of all, I would like to thank all authors who have contributed to this issue. The focuses of the articles are varied. Ayodele Ogunleye and Benjamin E. Anyaegbuna provided an assessment of physics laboratory teaching and learning resources in two Nigerian universities. Abdulrasaq Abdulkadir, Abdulkadir Olarewaju Rasa and Isıaka Gafar discussed implications for counselling in terms of psychological effects of retirement of retirees. Mehmet Aşıkcan and Ahmet Saban examined prospective teachers’ metacognitive awareness levels of reading strategies. In addition, Adile Emel Sardohan Yildirim and Gönül Akçamete investigated the views and suggestions about participation of families of children with special needs in individualised education programme.

Nevertheless, Pınar Koseoglu and Hulya Pehlivan carried out a research aiming to reveal the high school students’ metaphorical perceptions of biology and biology teacher concepts. Seval Orak and Cavide Demirci provided application examples and student views on active learning approach integrated with branches of art. Murat Tezer and Naciye Ataman studied the effect of university education on lifelong learning tendency. Lastly, Hayat Boz explained social relationship network and communication at old age.

Best Regards,

Prof. Dr. Huseyin Uzunboylu

Editor in Chief
The effect of university education on lifelong learning tendency
Authors: Tezer Murat , Ataman Naciye 
Published: April 2018

In this study, the effects of university education on lifelong learning tendencies of teachers and preservice teachers by some variables were aimed to analyse. In this study, survey model was used. The population of the study consists of the teachers serving in Turkey and the preservice teachers having been studying at Faculty of Arts at a university in 2016–2017 academic year and its samples consist of the first and second grade teachers and 3rd—4th grade preservice teachers. The effect of university education on lifelong learning tendency scale developed by researchers was used in this study. The findings obtained at the end of the study indicate that teachers have better lifelong learning tendency level than those of preservice teachers; there is a significant difference on behalf of females by just sex variable among age, professional seniority, branch variables.

Keywords: Lifelong learning tendency, university education, teacher, preservice teacher.
Social relationship network and communication at old age
Authors: Boz Hayat 
Published: April 2018

Old age is a period when the social environment of the elderly person shrinks due to reasons such as loss of social role, health, decline of income and empty nest situation. This research was carried out in order to determine, how elderly people use the social relationship networks and communication with their environment, to satisfy the needs for establishing relationships with other people, acceptance and belonging. In this study, interview technique was used as qualitative data collection method and four female and six male participants aged 65 and over were interviewed. Questions about socioeconomic and demographic characteristics, daily life activities and obstacles, social acquaintances, what kind of people they wanted to socialise with or not, their preferences in communication content, who they had been in conflict with in and why, were asked to participants. Among the daily activities, worshiping, listening to radio and watching television were done without gender difference, and it was found that not being able to ‘visit neighbours’ was in the first place among the activities that could not be done, but this was also prevented by their spouse, the daughter-in-law or the children. Their children and grandchildren were their main social acquaintances, and these were followed by relatives. They were mainly talking about the current events and politics. They preferred to talk to people with similar personality traits and people whom were generally acceptable to society. They, mainly, had conflicts with their daughters, spouse, daughter in-laws and siblings about not doing what they wanted or being obstructed about the things they wanted to do and have financial issues. Participants who had lost their spouse and participants who lost their peers felt loneliness and felt sad for being lonely. The participants felt health was the bad aspect of being old; and being able to worship as they wanted to and getting respect were good aspects of being old. The worry about the future was determined to be individual in some participants and general in others.

Keywords: Social relations in old age, communication conflicts in old age, communication content in old age.
Economic Environment and Entrepreneurial Development in Lagos and Ogun States, Nigeria
Authors: Jayeola OLABISI , T. OLAWALE OLADUNJOYE, , A. A. ADEWUMI, 
Published: April 2018

<p>The study empirically examines the relationship that exists between economic environment and entrepreneurial development in Nigeria. A structured questionnaire is administered on the study and data collected are analysed using Analysis of Variance and Regression. The following variables are indices of determination; Interest Rate (IR); Income Tax (IT).The results of the study show that there is a significant relationship between IR and ED in Nigeria (p&lt;0.5) with a positive correlation (r=0.526, r<sup>2</sup>=0.276). Also, there is a significant relationship between IT and ED in Nigeria (p&lt;0.05), with a positive association (r=0.546; r<sup>2</sup>=0.299). The study concludes that, the emergence of higher level of stable economic environment is critical to entrepreneurial development in Nigeria. Therefore, government involvement in public private partnership for infrastructural development, enlargement of productive, judicious and transparent use of funds collected from income tax and affordable interest rate will galvanise the inward sourcing of raw materials that boost entrepreneurial development in Nigeria. </p>
Scope of E-Healthcare Services in Uttar Pradesh with Special Reference to Varanasi
Authors: . Shivesh 
Published: April 2018

<p>Innovation in the field of Healthcare will create new landmarks in this field. The Health related information in any country is confidential and is available in large amount. Effective Management of Health Data is important. E-Health exists in various forms. Mostly, the People living in Urban Areas having each sort of facility like Mobile Phone and good Internet Connectivity but then also they do not know about the free services provided by the Hospitals. There is less awareness about E-Health services in India. In this paper we had discussed about the E-Health Initiatives in Uttar Pradesh, the E-Health Models, its Architecture and its scope in urban areas of Varanasi, in detail and how it is essential for the atomisation of Health Management System (H.M.S.). There are different forms of E-Health discussed in this paper like Automated Physician Order Entry, E- Prescribing, Decision Support System, M-Health and Health Informatics.</p>
3D Computational-Fluid-Dynamics Modeling of Horizontal Three-Phase Separators: An Approach for Estimating the Optimal Dimensions
Authors: Ghaffarkhah Ahmadreza , Shahrabi Mohammadjavad Ameri , Moraveji Mostafa Keshavarz 
Published: April 2018

Summary
This study presents an approach to determine the dimensions of three-phase separators. First, we designed different vessel configurations depending on the fluid properties of an Iranian gas/condensate field. We then devised a comprehensive computational-fluid-dynamics (CFD) method for analyzing the phenomena of three-phase separation. The results in terms of separation efficiency and behavior of secondary-phase particles were reviewed to choose the optimal configuration. Only a slight difference in the length of this vessel and the existing separator was found. In addition, simulation data were compared with industrial data pertaining to a similar existing separator. The results of this work showed that the CFD model used is capable of investigating the performance of three-phase separators.