bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mae Among the Stars by R. Ahmed
Authors: Harty Bridget 
Published: June 2019

Ahmed, Roda. Mae Among the Stars. Illustrated by Stasia Burrington, Harper Collins, 2018.
Mae Among the Stars is the perfect picture book for any young child (3-8) interested in space. It tells the real-life story of Mae Jemison, the first African American woman in space. This story urges children to explore even the most impossible dreams, or as Mae’s parents repeatedly encourage throughout: “If you can dream it, if you believe it and work hard for it, anything is possible.” The story revolves around the age-old question most of us are asked as children: What would you like to be when you grow up? Mae Jemison dreams about being an astronaut. Although her teacher tries to deter her from pursuing this dream, Mae refuses to give up. Thanks to her determination and parents’ reinforcement, she continues to work towards achieving her “impossible” dream of seeing Earth from space. Kids will find the last page of this book particularly interesting because it contains the bio of Mae Jemison and her accomplishments.
The illustrations in this book elevate the story to an exceptional level. The rich colours and imaginative drawings bring each page to life. The illustrations are so vivid that one page in particular stands out from the rest because it is depicted in a muted blue, representing Mae’s gloomy response to her teacher’s disapproval of her dream of becoming an astronaut. Although the story tackles the deep-rooted issues of racial and gender stereotypes, the writing is simple enough for young readers to connect with Mae’s story while still inspiring them to reach for the stars.
Recommended: 3 out of 4 starsReviewer: Bridget Harty
Bridget Harty is a University of Alberta undergraduate student in the Elementary Education program. She enjoys spending time with family and friends and rereading the Harry Potter series any chance she gets.
The Day You Begin by J. Woodson
Authors: Ford Danielle 
Published: June 2019

Woodson, Jacqueline. The Day You Begin. Illustrated by Rafael López, Penguin Random House, 2018.
Inspired by a poem in her award-winning memoir Brown Girl Dreaming, the Brooklyn based author Jacqueline Woodson wrote The Day You Begin about the moments in a child’s life when s/he feels like an outsider. Throughout the pages, the reader goes on a journey through the eyes of various children and their experiences feeling like outsiders. The children discover that the moment you bravely reach out you will find that “every new friend has something a little like you—and something else so fabulously not quite like you at all.” Written in beautifully poetic text that is perfectly portrayed through the illustrations, this picture book speaks of hope and human connection in the face of fear, a concept easily connected to by all.
Rafael Lopez creates beautiful illustrations to inspire imagination and conjure up the precious richness of our differences. Pages filled with vibrant images of flowers and nature are used to represent the child’s unique qualities spoken of in the text. In contrast, dull colours and minimal images express feelings of difference. The highly relatable experience of trying to measure up is illustrated on some of the pages through the presence of a ruler. Adults and children of all ages will be able to connect in some way with the characters on the page.
Overall, this is a beautifully written book that can be used to discuss the vibrancy we can find in our communities when we cherish our differences and share of ourselves, if only we would begin.
Highly Recommended: 4 out of 4 starsReviewer: Danielle Ford
Danielle is an avid reader of all kinds of books. Currently in her last semester of her Bachelor of Education as an Elementary Generalist, she is looking forward to bringing rich children’s literature into her classroom.
We Don’t Eat Our Classmates by R.T. Higgins
Authors: Oliver Haley 
Published: June 2019

Higgins, Ryan T. We Don’t Eat Our Classmates. Disney-Hyperion, 2018.
Ryan T. Higgins writes highly rated children’s books dealing with common elementary school conflicts. The picture book, We Don’t Eat Our Classmates, will capture all readers, no matter the age. The main character, Penelope, is an adorable T-rex who wears pink coveralls. She was designed by the illustrator and a group of children so it has features that will appeal to all and capture your heart immediately. Penelope is a having a rough first day of school because she keeps eating all her classmates; she struggles with fitting in but learns that it is not fun when you get bit. The story uses humorous hyperboles and the element of surprise that will keep the reader engaged until the end of the story. The humour is exemplified through the beautifully illustrated representations of the story. The illustrations capture the situations through simple images that show the character’s expressions and intentionally incorporate colours to emphasize the characters or the problem at hand.
This picture book would make a fantastic addition to any early elementary classroom and would make a great read aloud because it uses humour to address the themes of new students, making friends, and learning to treat others the way you want to be treated. Its huge font will allow younger readers to follow along. The humour and overemphasis in the story is what makes it a truly engaging and fun read while hitting on the feelings of being different and excluded that many students face.
Highly Recommended: 4 out of 4 starsReviewer: Haley Oliver
Haley Oliver is a fourth year Bachelor of Elementary Education student at the University of Alberta. She is interested in encouraging young child to love reading through entertaining and meaningful literature.
I Walk With Vanessa: A Story About a Simple Act of Kindness by Kerascoët
Authors: Beach Terri 
Published: June 2019

Kerascoët. I Walk With Vanessa: A Story About a Simple Act of Kindness. Random House Children’s Books, 2018.
This is a wordless picture book from French illustrators, Kerascoët. This husband and wife duo, Marie and Sébastien solely illustrate, without the use of text, the ability to combat bullying in modern society. They accomplish this difficult task by placing emphasis on the characters’ emotions through the use of distinct colour throughout the images, clearly depicting the story’s message. Because there are no words, this amazing resource provides students with the ability to interpret the book individually, creating unique perspectives such as an idea, "who else needs help other than Vanessa?"
This book provides fresh insight into how society can unite together by creating a positive chain reaction when faced with bullying. Throughout the illustrations, this team accomplished this task extremely well, by providing the audience with diverse characters, creating a sense of belonging. This allows the reader to view the characters as if they were looking at their own reflection, seeing into their lives, therefore enabling them to relate to the book. With this, I truly believe that it is essential for children's books to act either as a window or a mirror for children.
Overall, I feel that this book is ideal for a target audience of pre-kindergarten to grade two. The drawings are simplistic, with few details, allowing children to predict the storyline easily, leaving a thorough investigation of the book. I cannot wait for students to "read" this book to me.
Highly recommended: 4 out of 4 starsReviewer: Terri Beach
Management of atypical mucosal lesions from primary endodontic infection
Authors: Sirino Guilherme de Jesus Souza , Costa Susilena Arouche , Pereira Erika Martins , Souza Soraia de Fátima Carvalho 
Published: June 2019

Aim/Case report: We have described here the diagnosis and treatment of two cases involving atypical mucosal lesions originating from primary endodontic infections in young patients. Differential diagnoses were established by clinical and radiographic examinations. In both the cases, a red-colored lesion was observed in the alveolar mucosa, with a soft consistency and a sessile-base without any drainage path in tooth 31 (case 1) and with a sinus tract in tooth 36 (case 2), as confirmed by X-ray. The cleaning and shaping of the root canals were performed, and camphorated paramonochlorofenol (CPMC)-enriched calcium hydroxide paste was used as an intracanal dressing for 6 months, with replacement every 60 days. Conclusion: Based on our experience, we thus conclude that long-term root canal maintenance with CPMC-enriched calcium hydroxide was an effective therapeutic protocol for promoting the healing of atypical mucosal lesions.
Methods and logistics of an oral health cohort of university students from Pelotas, a Brazilian Southern city
Authors: Chisini Luiz Alexandre , Cademartori Mariana Gonzalez , Collares Kauê , Tarquinio Sandra Beatriz Chaves , Goettems Marília Leão , Demarco Flávio Fernando , Corrêa Marcos Britto , Azevedo Marina Souza 
Published: June 2019

Aim: This paper aimed to describe the methodological aspects in the baseline of university students’ cohort in a public university in southern Brazil. Methods: A multidisciplinary study was carried out assessing the psychosocial and oral health conditions of university students at the Federal University of Pelotas (UFPel). All new university students who have entered in in UFPel in the first semester of 2016 year were invited to participate. Two self-administered questionnaires were applied in classrooms. Descriptive analysis was performed using Stata 14.0. Results: A total of 3,237 students were eligible. Of these, 2,089 (64.5%) signed the consent form to participate of the study and answered the general questionnaires, and 2,052 (63.4%) students answered the confidential questionnaire. Refuses represented only 1.4% (n=29) of the total sample. Overall, most of the sample was female (52.2%), with age ranging from 18 to 24 years (66.1%), with white skin color (74.1%) and with mothers with educational level at university course (32.4%). A total, 62% reported a family income between 1001.00 and 5000.00 BRL, while only 16.3% reported being from low-income family (≤ 1000.00 BRL). The UFPel offers 63 classroom-based courses classified in nine areas of knowledge. The Applied Social Sciences area comprised 19% of the sample followed by the Linguistics, Letters and Arts (17%) area and the Health sciences area (13%). Conclusion: To the knowledge of researchers, this was the first cohort study of university students in the South of Brazil including more than two thousand participants. This paper described strategies adopted to optimize and to allow data collection in the baseline and in the next follow-ups.
Nonoperative Treatment Compared with Volar Locking Plate Fixation for Dorsally Displaced Distal Radial Fractures in the Elderly
Authors: Saving Jenny , Severin Wahlgren Sara , Olsson Kristin , Enocson Anders , Ponzer Sari , Sköldenberg Olof , Wilcke Maria , Mellstrand Navarro Cecilia 
Published: June 2019

Background:
The usage of volar locking plate fixation for distal radial fractures has increased in older patient populations, despite the fact that surgical treatment in the elderly population has not clearly been proven to be superior to nonoperative treatment. The purpose of the present study was to compare nonoperative treatment with volar locking plate fixation with regard to clinical outcome for elderly patients with dorsally displaced distal radial fractures.

Methods:
In this study, 140 patients were randomly allocated to nonoperative treatment with a plaster splint (n = 72) or volar locking plate fixation (n = 68). The outcome variables were the Patient-Rated Wrist Evaluation (PRWE) score, Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire score, EuroQol-5 Dimensions (EQ-5D) score, range of motion, grip strength, radiographic outcomes, and complications. Evaluation was performed at 3 and 12 months by unblinded observers.

Results:
At 3 months, 122 patients were evaluated, and at 12 months, 119 patients were evaluated. At 3 months, the volar locking plate group, compared with the nonoperative treatment group, had a better median PRWE score (10.3 compared with 35.5 points; p = 0.002), DASH score (14.4 compared with 29.2 points; p = 0.016), and grip strength (71.0% of the uninjured hand compared with 53.9%; p < 0.001). Significant differences in favor of the volar locking plate group remained at 12 months; compared with the nonoperative treatment group, the volar locking plate group had a better median PRWE score (7.5 points compared with 17.5 points; p = 0.014), DASH score (8.3 points compared with 19.9 points; p = 0.028), and grip strength (96.8% compared with 80.0%; p = 0.001). Radiographic measurements favored volar locking plate fixation at 3 and 12 months. Complication rates were similar, with 11% major complications in the nonoperative group compared with 14% major complications in the volar locking plate group (p = 0.606) and 11% minor complications in the nonoperative group compared with 20% minor complications in the volar locking plate group (p = 0.197).

Conclusions:
The PRWE scores, DASH scores, and grip strength were better for the volar locking plate group compared with the nonoperative group at 3 and 12 months. The complication rates were similar. Our results imply that there is a benefit for the elderly patient with an unstable dorsally displaced distal radial fracture to be treated with a volar locking plate.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Disclosures Undisclosed
Authors: Janney Cory F. , Shazadeh Safavi Kiya , Schneider Gregory J. , Jupiter Daniel C. , Panchbhavi Vinod K. 
Published: June 2019

Background:
The Centers for Medicare & Medicaid Services (CMS) Open Payments public database, resulting from the Physician Payments Sunshine Act of 2010, was designed to increase transparency of physicians’ financial relationships with pharmaceutical manufacturers. We compared physician-reported conflict-of-interest (COI) disclosures in journal articles with this database to determine any discrepancies in physician-reported disclosures.

Methods:
COIs reported by authors from 2014 through 2016 were analyzed in 3 journals: Foot & Ankle International (FAI), The Journal of Bone & Joint Surgery (JBJS), and The Journal of Arthroplasty (JOA). Payment information in the CMS Open Payments database was cross-referenced with each author’s disclosure statement to determine if a disclosure discrepancy was present.

Results:
We reviewed 3,465 authorship positions (1,932 unique authors) in 1,770 articles. Within this sample, 7.1% of authorships had a recorded undisclosed COI (disclosure discrepancy), and 13.2% of articles had first and/or last authors with a disclosure discrepancy. Additionally, we saw a great variation in the percentage of authorships with disclosure discrepancies among the journals (JBJS, 2.3%; JOA, 3.6%; and FAI, 23.7%).

Conclusions:
Discrepancies exist between payment disclosures made by authors and those published in the CMS Open Payments database. Although the percentage of articles with these discrepancies varies widely among the journals that were analyzed in this study, no trend was found when analyzing the number of discrepancies over the 3-year period.

Clinical Relevance:
COI disclosures are important for the interpretation of study results and need to be accurately reported. However, COI disclosure criteria vary among orthopaedic journals, causing uncertainty regarding which conflicts should be disclosed.
Postprandial transfer of colostral extracellular vesicles and their protein and miRNA cargo in neonatal calves
Authors: Kirchner Benedikt , Buschmann Dominik , Paul Vijay , Pfaffl Michael W. 
Published: June 2019

Abstract
Background
Extracellular vesicles (EVs) such as exosomes are key regulators of intercellular communication that can be found in almost all bio fluids. Although studies in the last decade have made great headway in discerning the role of EVs in many physiological and pathophysiological processes, the bioavailability and impact of dietary EVs and their cargo still remain to be elucidated. Due to its widespread consumption and high content of EV-associated microRNAs and proteins, a major focus in this field has been set on EVs in bovine milk and colostrum. Despite promising in vitro studies in recent years that show high resiliency of milk EVs to degradation and uptake of milk EV cargo in a variety of intestinal and blood cell types, in vivo experiments continue to be inconclusive and sometimes outright contradictive.
Results
To resolve this discrepancy, we assessed the potential postprandial transfer of colostral EVs to the circulation of newborn calves by analysing colostrum-specific protein and miRNAs, including specific isoforms (isomiRs) in cells, EV isolations and unfractionated samples from blood and colostrum. Our findings reveal distinct populations of EVs in colostrum and blood from cows that can be clearly separated by density, particle concentration and protein content (BTN1A1, MFGE8). Postprandial blood samples of calves show a time-dependent increase in EVs that share morphological and protein characteristics of colostral EVs. Analysis of miRNA expression profiles by Next-Generation Sequencing gave a different picture however. Although significant postprandial expression changes could only be detected for calf EV samples, expression profiles show very limited overlap with highly expressed miRNAs in colostral EVs or colostrum in general.
Conclusions
Taken together our results indicate a selective uptake of membrane-associated protein cargo but not luminal miRNAs from colostral EVs into the circulation of neonatal calves.
Treatment outcomes and antiretroviral uptake in Multidrug-Resistant Tuberculosis and HIV coinfected Patients in Sub Saharan Africa. A Systematic Review and Meta-Analysis
Authors: Chem Elvis Dzelamonyuy , Hout Marie Claire Van , Hope Vivian 
Published: June 2019

Abstract
Background

Multidrug-resistant tuberculosis (MDR-TB) in HIV endemic settings is a major threat to public health. MDR-TB is a substantial and underreported problem in Sub-Saharan Africa (SSA), with recognised cases projected to increase with advancement in diagnostic technology. There is paucity of review evidence on treatment outcomes and antiretroviral (ART) uptake among MDR-TB patients with HIV in SSA. To address this gap a review of treatment outcomes in HIV patients co-infected with MDR-TB in the SSA region was undertaken.

Methods

Three databases (Medline, Web of Science, CINHAL), Union on Lung Heath conference proceedings and grey literature were searched for publications between January 2004 and May 2018. Records were assessed for eligibility and data extracted. Random effect meta-analysis was conducted using STATA and Cochrane’s review manager.

Results

A total of 271 publications were identified of which nine fulfilled the inclusion criteria. Data was collected from 3,368 MDR-TB and HIV co-infected patients from four SSA countries; South Africa (6), Lesotho (1), Botswana (1) and Ethiopia (1). The most common outcome was cure (34.9% cured in the pooled analysis), this was followed by death (18.1% in pooled analysis). ART uptake was high, at 83% in the pooled analysis. Cure ranged from 22.2% to 57.7% among patients on ART and from 28.6% to 54.7% among those not on ART medication. MDR-TB and HIV coinfected patients were less likely to be successfully treated than HIV negative MDR-TB patients (Risk Ratio = 0.87, 95% CI 0.97, 0.96).

Conclusion

Treatment outcomes for MDR-TB and HIV coinfected patients do not vary widely from those reported globally. However, treatment success was lower among HIV positive MDR-TB patients compared to HIV negative MDR-TB patients. Prompt antiretroviral initiation and interventions to improve treatment adherence are necessary.
Comparative transcriptomics of Gymnosporangium spp. teliospores reveals a conserved genetic program at this specific stage of the rust fungal life cycle
Authors: Tao Si-Qi , Cao Bin , Morin Emmanuelle , Liang Ying-Mei , Duplessis Sébastien 
Published: June 2019

Abstract
Background

Gymnosporangium spp. are fungal plant pathogens causing rust disease and most of them are known to infect two different host plants (heteroecious) with four spore stages (demicyclic). In the present study, we sequenced the transcriptome of  G. japonicum teliospores on its host plant Juniperus chinensis and we performed comparison to the transcriptomes of G. yamadae and G. asiaticum at the same life stage, that happens in the same host but on different organs.

Results

Functional annotation for the three Gymnosporangium species showed the expression of a conserved genetic program with the top abundant cellular categories corresponding to energy, translation and signal transduction processes, indicating that this life stage is particularly active. Moreover, the survey of predicted secretomes in the three Gymnosporangium transcriptomes revealed shared and specific genes encoding carbohydrate active enzymes and secreted proteins of unknown function that could represent candidate pathogenesis effectors. A transcript encoding a hemicellulose of the glycoside hydrolase 26 family, previously identified in other rust fungi, was particularly highly expressed suggesting a general role in rust fungi. The comparison between the transcriptomes of the three Gymnosporangium spp. and selected Pucciniales species in different taxonomical families allowed to identify lineage-specific protein families that may relate to the biology of rust fungi. Among clustered gene families, 205, 200 and 152 proteins were specifically identified in G. japonicum, G. yamadae and G. asiaticum, respectively, including candidate effectors expressed in teliospores.

Conclusions

This comprehensive comparative transcriptomics study of three Gymnosporangium spp. identified gene functions and metabolic pathways particularly expressed in teliospores, a stage of the life cycle that is mostly overlooked in rust fungi. Secreted protein encoding transcripts expressed in teliospores may reveal new candidate effectors related to pathogenesis. Although this spore stage is not involved in host plant infection but in the production of basidiospores infecting plants in the Amygdaloideae, we speculate that candidate effectors may be expressed as early as the teliospore stage for preparing further infection by basidiospores.
Efficacy of electro-acupuncture and manual acupuncture versus sham acupuncture for knee osteoarthritis: statistical analysis plan for a randomized controlled trial
Authors: Tu Jian-Feng , Yang Jing-Wen , Wang Li-Qiong , Wang Yang , Li Jin-ling , Zhang Na , Lin Lu-Lu , Yu Zhang-Sheng , Liu Cun-Zhi 
Published: June 2019

Abstract
Background: Acupuncture therapies are widely used for knee osteoarthritis (KOA), despite contradictory evidences. Current study is designed to determine the efficacy of electro-acupuncture and manual acupuncture versus sham acupuncture for KOA.
Methods/design: Current study is a multi-center, three-arm, randomized controlled trial which will enroll 480 participants with KOA in China. Participants will be randomly assigned (1:1:1) to receive 24 sessions of electro-acupuncture, manual acupuncture, or sham acupuncture over 8 weeks. The primary outcome is the response rate - the proportion of patients who simultaneously achieve minimal clinically important improvement in pain and function domains at 8 weeks. The primary outcome will be analyzed using Z-test with intention-to-treat set. Secondary outcomes contain pain, function, global patient assessment and quality of life. Full details of the statistical analysis plan for the primary and secondary outcomes will be described in this article. The statistical analysis plan was written and submitted without knowledge of the study data.
Discussion: The data will be analyzed according to this pre-specified statistical analysis plan to avoid data-driven analysis and enhance the transparency of current trial. The trial will provide high-quality evidence on the efficacy of acupuncture for KOA.