bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of match-running distances covered by soccer players during the UEFA EURO 2016
Authors: Kubayi A 
Published: August 2019

Background: Despite a substantial body of literature on match-running distances covered by soccer players in domestic leagues, there appears to be limited information on the Union of European Football Associations (UEFA) Euro competitions.
Objective: The aim of this study was to analyse the match-running distances covered by soccer players during the UEFA Euro 2016.
Methods: A multiple-camera tracking system (InStat Ltd) was used to analyse 228 observations of soccer players who played 15 full matches during the tournament. The outfield players were categorised according to the following playing positions: central defenders (CDs), n=58; wide defenders (WDs), n=45; central midfielders (CMs), n=53, wide midfielders (WMs), n=38; and attackers (ATs), n=34. Data were reported as means with 95% confidence intervals (CI). A one-way analysis of variance (ANOVA) was undertaken to examine the significant differences among players based on playing positions.
Results: The results indicated that the overall total distance covered by players was 10 350 m, ranging from 8 446 m to 12 982 m. ATs covered the longest distance in high-speed running (872 m; 95% CI = 813–931), while CDs covered the shortest distance (542 m; 95% CI = 503–581). A statistically significant difference was observed in high-speed running among players (F (4 223) = 36.92, P=0.001).
Conclusion: The findings of this study provide soccer scientists and coaches with important information to design and implement training sessions in order to elucidate the physical demands of players in view of successful team performance.
POTENTIAL OF AGROENERGY RESIDUES FOR THE GENERATION OF BIOGS IN THE STATE OF TOCANTINS
Authors: Martins Denise Domingos dos Santos , Serra Juan Carlos Valdés 
Published: August 2019

Concerns over the depletion of traditional fossil energy sources and the consequent greenhouse effect generated by the use of fossil fuels have increased, creating a need to search for alternative sources of clean energy. Thus, this work had the objective of portraying the potential of residues from agroenergy in the State of Tocantins for generation of Biogas. This article was developed under the principle of the exploratory study, through data surveys from the State. The agroenergy residues researched were soybean, cassava (manioc), rice, sugarcane, maize, sorghum and beans. The energy potential of the studied residues represents 3.56% of the energy generation capacity by biomass sources. The source of highest agroenergy potential for biogas generation was maize, with an energy capacity of 498.90 MW. The use of biomass as an energy source presents itself as an interesting alternative in the survey carried throughout this work.
IRRADIAÇÃO SOLAR GLOBAL PARA CIDADE DE MAPUTO - MOÇABIQUE: EVOLUÇÃO TEMPORAL DAS MEDIDAS E MODELAGEM ESTATÍSTICA
Authors: Fernando Domingos Mário Zeca , Calca Marcus Vinicius Contes , Raniero Matheus Rodrigues , Dal Pai Alexandre 
Published: August 2019

IRRADIAÇÃO SOLAR GLOBAL PARA CIDADE DE MAPUTO - MOÇABIQUE: EVOLUÇÃO TEMPORAL DAS MEDIDAS E MODELAGEM ESTATÍSTICA

DOMINGOS MÁRIO ZECA FERNANDO¹; MARCUS VINÍCIUS CONTES CALÇA²; MATHEUS RODRIGUES RANIERO³ E ALEXANDRE DAL PAI4

¹Departamento de Ciências Naturais e Matemática, Universidade Púnguè, Bairro Heróis Moçambicanos, C. Postal: 323, Cidade de Chimoio, Moçambique, e-mail: dmzeca@gmail.com.
2Departamento de bioprocessos e biotecnologia, Universidade Estadual Paulista, Av. Universitária, nº 3780 - Altos do Paraíso, Botucatu - SP, 18610-034, Brasil, e-mail: mcontes@outlook.com.
3Departamento de bioprocessos e biotecnologia, Universidade Estadual Paulista, Av. Universitária, nº 3780 - Altos do Paraíso, Botucatu - SP, 18610-034, Brasil, e-mail: matheus.raniero@hotmail.com.
4Departamento de bioprocessos e biotecnologia, Universidade Estadual Paulista, Av. Universitária, nº 3780 - Altos do Paraíso, Botucatu - SP, 18610-034, Brasil, e-mail: dal.pai@unesp.br.

RESUMO: A equação de Angstrom continua sendo a relação mais usada para se estimar a irradiação solar global média diária a partir das horas de brilho solar, em localidades onde a medição não seja contínua ou os equipamentos não estejam disponíveis. O objetivo deste trabalho foi de apresentar a evolução das medidas de irradiação solar e das horas de brilho solar e determinar os coeficientes de Angstrom para estimativa da irradiação solar global na cidade de Maputo. A média da irradiação solar global na cidade de Maputo foi de 17,96 MJ/m² e as horas de brilho solar foram de 7,8 horas. Os coeficientes “a” e “b” do modelo anual para estimativa da irradiação solar global na cidade de Maputo são 0,23 e 0,49 respetivamente.

Palavras-chaves: brilho solar, estimativa irradiação solar global, modelo de angstrom.

GLOBAL SOLAR IRRADIATION FOR MAPUTO CITY - MOZAMBIQUE: TEMPORAL EVOLUTION OF MEASUREMENTS AND STATISTICAL MODELING

ABSTRACT: The Angstrom equation continues to be the most used relation to estimate the daily average global solar irradiation from sunshine, in places where measurement is not continuous or equipment is not available. The aim of this work was to present the evolution of solar radiation and sunshine measurements and to determine the Angstrom coefficients to estimate global solar irradiation in the city of Maputo. The average of the global solar irradiance in the city of Maputo was 17.96 MJ/m² and sunshine average was 7.8 hours. The coefficients "a" and "b" of the annual model for estimation of global solar irradiation in the city of Maputo were 0.23 and 0.49, respectively.

Keywords: sunshine, estimation of global solar irradiation, Angstrom model.
Clinical and prognostic value of the residual activity of platelets in patients with acute coronary syndrome without st segment elevation
Authors: Stoyko O. A. , Shalaev S. V. 
Published: August 2019

Aim. To study clinical prognostic value of residual platelet activity in patients with acute coronary syndrome without ST segment elevation. Material and methods. The study included 120 patients with acute coronary syndrome without ST segment elevation (NSTE ACS) with coronary artery stenting. Testing of residual reactivity of platelets in the subjects was carried out after loading doses of aspirin and P2Y12-inhibitors.Patients were divided into two groups comparable in gender and age: with low residual reactivity of platelets (LRR), n=90 and with high residual reactivity of platelets (HRR), n=30. Between the groups a comparative assessment of clinical-laboratory and instrumental indicators, development of a combined end point (ischemic events) and bleeding during follow-up (16 ± 6 months). Results. The group with HRR was initially heavier: patients with angina pectoris of functional class III, atrial fibrillation, myocardial infarction, was a higher risk on the GRACE (202,6±11 vs. 148,6±7, р=0,03),increased levels of Troponin T (70,0 vs. 45,5%, р=0,02), acute occlusion in the coronary arteries (66,6 vs. 42,4%, р=0,02).The combined endpoint was more often reported in patients with HRR (40 vs. 20,7%, р=0,04). Patients with ADP-aggregation of platelets in the range 0–1 Om had a greater risk of developing hemorrhagic events (17,1 vs. 2,1%, RR 8,05 CI: 1,1–59,9, р=0,01). Conclusion. In patients with NSTE ACSHRR after loading doses of aspirin and P2Y12-inhibitor was associated with the development of repeated atherothrombotic events. Very low LRR was associated with the development of bleeding.
Body fat indices for identifying risk of hypertension in Indian children
Authors: S. Vairamuthu G. , A. Thangavel 
Published: August 2019

Background: Studies in India shown high body fat indices were strongly associated with hypertension in Indian children, but such studies mostly not done in southern states of India. So, authors include children in Tamilnadu measure body fat indices and blood pressure to find which body fat index correlates closely with hypertension.Methods: Standing height was measured using stadiometer. Weight was measured using electronic scale. WC measured in standing position, by a stretch resistant. WC above 90th centile will be considered as Adipose. Waist to height ratio optimal cut-off value is 0.44 for children. TSFT recorded using Harpenden caliper, on the non-dominant upper arm. Wrist circumference measured using stretch resistant tape.Results: In this study 2000 children were participated. More hypertensives are seen in 10 to 12 years(62) and 16 to 18 years(31).Increased weight correlated with hypertension. Study indicates waist circumference is significantly correlated with systolic BP p<0.003, diastolic BP p<0.000. This study shows significant correlation p<0.003 for systolic and p<0.000 for diastolic BP with triceps skin fold thickness estimation. In multivariate analysis with systolic blood pressure and diastolic blood pressure shows very strong correlation with waist circumference, waist to height ratio and triceps skin fold thickness.Conclusions: In this study we investigate the correlation between body fat indices and blood pressure correlation was statistically analyzed which shows that waist circumference, waist to height ratio and triceps skin fold thickness were strongly correlated with systolic and diastolic BP.
Paroxysmal hypertension with reversible posterior leukoencephalopathy syndrome in a child: an unresolved riddle
Authors: Thomas Mili , Nair Veena V. , Hrishikesan Lekha , Swarnam Kamala 
Published: August 2019

Nine year old girl was presented with paroxysmal episodes of hypertensive emergency. She was asymptomatic with normal blood pressure without antihypertensives in between the episodes. MRI brain was suggestive of reversible posterior leukoencephalopathy. Acute episodes were managed with IV labetalol infusion and amlodipine. She was evaluated extensively to find out the etiology of hypertension. Cardiac and renal causes were ruled out. Work up for pheochromocytoma, hyperaldosteronism, porphyria and vasculitis were negative. The case is reported in view of the rare presentation and the leukoencephalopathy noted in this case.
Production of L-asparaginase by Aspergillus niveus under solid-state fermentation using agroindustrial byproducts
Authors: Da Silva Amatto Isabela Victorino , Guimarães Luis Henrique Souza 
Published: August 2019

<p class="abstract"><strong>Background:</strong> L-asparaginase, produced mainly by microrganisms, cleaves L-asparagine to aspartic acid and ammonia as products. This enzyme has been applied in the treatment of the leukemia and in food preparation preventing the acrylamide formation.</p><p class="abstract"><strong>Methods:</strong> <em>Aspergillus niveus</em> was grown in different solid substrates (agroindustrial byproducts) moistened with different agents (tap water, distilled water and several salt solutions) for different periods (24-240 h) at 30ºC. The enzyme extract was obtained with the addition of cold distilled water, agitation at 50 rpm for 30 min and filtration. The filtrate was used to determine the L-asparaginase activity through the hydroximate aspartic methodology using L-asparagine as substrate. The influence of temperature (30-75ºC), pH (3-9) and chemical compounds on the enzyme activity was analyzed. </p><p class="abstract"><strong>Results:</strong> The highest level of enzyme production was obtained using the M1 mixture (wheat bran, crushed soybean, orange peel; 1:1:1, w/w/w) as substrate humidified with Czapeck Dox salt solution (1:0.5, m/v) for 48-120 h, at 30ºC. The best temperature and pH for the enzyme activity were 35ºC and 5.0, respectively. The enzyme activity was increased in the presence of NaCl and some organic solvents (acetonitrile, butanol ethanol, isopropanol and methanol).</p><p class="abstract"><strong>Conclusions:</strong> <em>A. niveus</em> produced L-asparaginase under SSF using a mixture of agroindustrial byproducts as solid substrate in the absence of L-asparagine as inducer. The temperature and pH of activity, as well as the NaCl tolerance, indicate its potential to be applied for different purposes. <em>A. niveus</em> can be an interesting source of L-asparaginase gene to be investigated targeting future application.</p><p class="abstract"> </p>
Avanços científico-tecnológicos e Auto(trans)formação de professores: novos tempos ... velhos desafios?!
Authors: Dos Santos de Andrade Toniolo Joze Medianeira , Ilgo Henz Celso , Goelzer Juliana , Hennicka Micheli 
Published: August 2019

Vivemos tempos de rápidas mudanças, sobretudo decorrentes dos avanços científicos e tecnológicos, que trazem consigo outras caracterizações na sociedade e no cotidiano das pessoas, mudando formas de interagir no e com o mundo. Esses novos tempos trazem, também, novas presenças no atual cenário educacional, bem como nas formas de ser, fazer, conviver, aprender, predominantemente influenciadas pela era tecnológica. Diante dessas inúmeras transformações, a escola ainda enfrenta o velho desafio de reconhecer essas mudanças e suas influências nas relações político-pedagógicas com os estudantes e a sociedade. Contudo, ainda não é esta a escola que temos; e esta realidade desafiadora nos coloca também diante da necessidade de uma maior atenção aos processos de auto(trans)formação com professores, entendendo esses como o primeiro passo na busca de outras formas de sentir/pensar/agir desses profissionais. Assim, as inovações e transformações científico-tecnológicas também passam a ser possíveis aliadas na educação nos/dos novos tempos, com processos de ensino-aprendizagens significativos para crianças, adolescentes, jovens e adultos do século XXI.
An improved deyolking procedure facilitates the proteomics analysis of early developmental stages of zebrafish embryos
Authors: Kathiresan Purushothaman , Presslauer Christopher , Das Prem Prakash , Kwang Lim Teck , Johansen Steinar Dae , Lin Qingsong , Babiak Igor 
Published: August 2019

Abstract
Background: Zebrafish is a well-recognised organism for investigating vertebrate development and human diseases. However, the data on zebrafish proteome are scarce, particularly during embryogenesis. This is mostly due to the overwhelming abundance of egg yolk proteins, which tend to mask the detectable presence of less abundant proteins. Results: In this study, we developed an efficient procedure to reduce the amount of yolk in zebrafish early embryos to improve the LC-MS-based shotgun proteomics analysis. We demonstrated that the deyolking procedure resulted in a greater number of proteins being identified. This protocol resulted in approximately two-fold increase in the number of proteins identified in deyolked samples at cleavage stages, and the number of identified proteins increased greatly by 3-4 times compared to non-deyolked samples in both oblong and bud stages. Gene Ontology and KEGG analysis revealed a high number of functional proteins differentially accumulated in the deyolked versus non-deyolked samples. The most prominent enrichments after the deyolking procedure included processes, functions and components related to cellular organization, cell cycle, control of replication and translation, and mitochondrial functions. Conclusion: This deyolking procedure improves both qualitative and quantitative proteome analyses and provides an innovative tool in molecular embryogenesis of polylecithal animals, such as fish, amphibians, reptiles, or birds.
Knowledge, attitudes, and use of family planning methods among female secondary school students in Tanzania
Authors: Ayubu Agnes Enock , Mwasha Loveluck Kusiriel , Kabeya Lucia Damian 
Published: August 2019

Abstract
Background The secondary school student population comprises adolescents aged 12–19 years, who represent around 15% of the global population. The Many adolescents are sexually active and at high risk for unwanted/unintended pregnancies and sexually transmitted infections; however, access to family planning (FP) services for this group is limited. Girls are more susceptible to sexual reproductive health problems than boys, and are less likely to use contraceptives. Despite these challenges, there are few studies on knowledge and attitudes about FP methods among female secondary school students. This study aimed to assess knowledge, use, and attitudes toward FP methods among female secondary school students in Ilala, Dar es Salaam, Tanzania. Methods A descriptive cross section study was conducted from February to April 2017 among 120 female secondary school students, using multi-stage sampling. Data were collected using a structured self-administered questionnaire. Descriptive and inferential statistics were used to examine relationships between participants’ knowledge, attitudes, and use of FP methods. Results Most (93.33%) participants had heard about FP methods, but the majority (85.8%) had low knowledge about how these methods functioned. Although 70.83% of participants had a positive attitude toward FP methods, 29.17% thought they were at risk for sexually transmitted diseases and pregnancy, and few (8.33%) had used FP. There was a significant relationship between awareness and use of FP methods (p=0.003). Conclusion Female secondary school students in Tanzania have low knowledge of FP methods. Knowledge of FP methods can help to prevent the consequences of unprotected sex among adolescent girls, and assessment of their knowledge and attitudes regarding FP methods will help in designing and implementing appropriate interventions. Key words: Family planning, knowledge, attitude, family planning method use, adolescent, student
Regulatory role of programmed cell death 4 in precancerous gastric lesions and early gastric cancer
Authors: Zhu Yaodong , Liu Lei , Peng Qiang , Ba He , Song Wanji , Dong Wenqing , Li Ping , Zhang Mei 
Published: August 2019

Abstract
Background
Programmed cell death 4 (PDCD4) as a newly identified tumor suppressor is involved
in inhibiting tumorigenesis and tumor progression. Epithelial mesenchymal Transition (EMT) is also associated with tumorgenesis of gastric cancer. However, few studies have elucidated the role of PDCD4 in regulation of EMT during precancerous gastric lesions (PLGC) and early gastric cancer.
Methods
In this study, the expression of PDCD4 and EMT-associated proteins in PLGC and early gastric cancer tissues were detected by immunohistochemistry. The relationship between the expression of PDCD4 and EMT-associated proteins and clinical and pathological parameters were analyzed. The PDCD4 high-expressed SGC-7901 cell line was also used to evaluate the function of PDCD4 in vitro and in vivo.
Results
PDCD4 and EMT associated proteins expression were significantly altered in PLGC and early gastric cancer tissues. After transfection with the PDCD4 gene, the expression of E-cadherin was significantly increased, the expression of N-cadherin and Vimentin were also remarkably inhibited. PDCD4 high-expressed also inhibited tumor growth and pathological features in nude mice xenograft model.
Conclusion
This study elucidates a regulatory role of PDCD4 in PLGC and early gastric cancer and provide insights into EMT-associated target which may provide novel therapeutic recourse.
Management and leadership competence for hospital managers: a systematic review and best fit framework synthesis
Authors: KAKEMAM Edris , LIANG Zhanming , JANATI Ali , ARAB-ZOZANI Morteza , MOHAGHEGH Bahram , GHOLIZADEH Masoumeh 
Published: August 2019

Abstract
Background Competent managers are vital to the productivity and service quality of healthcare organizations and the sustainability of the healthcare system including hospitals. The purpose of this study is to synthesize the evidence related competency to management and leadership in healthcare organizations including hospitals through the Best Fit Method. Methods A systematic literature review was performed to identify studies focusing on confirming and/or assessing the competency requirements of health service managers in particular hospital managers. The following electronic databases were searched from January 2000 and December 2018: ISI/Web of Sciences, PubMed, Scopus, Emerald, and the Scientific Information Database. Applying the Best Fit Framework Synthesis Method, we mapped all of the competency and associating behavioral items against the validated MCAP management competency framework which includes 6 core competencies, 18 subthemes and 83 associating behavioural items. Results Eleven studies were identified for inclusion in the review. The mapping of the competencies and relevant items identified in these studies with the validated MCAP management competency framework and associating items confirm that the MCAP framework has vastly represented findings of all recent studies. Although the MCAP framework incorporated behavioral items associating with the competency of Professionalism into the six core competencies, the study found the necessity of treating Professionalism as an independent competency to be included in the global management competency framework for health service managers, in particular hospital managers. As a result, the proposed Global Management Competency Framework includes the following 7 competencies: evidence-informed decision making, operations, administration and resource management, knowledge of healthcare environment and the organization, interpersonal, communication qualities and relationship management, leading people and organisation, enabling and managing change, and professionalism. Conclusions This review and the mapping of the competencies identified in previous studies with the validated MCAP framework resulted in the recommendation of Global Management Competency Framework for health service managers. It provides useful guidance to the formulation of training and development direction for the health service management workforce. However, since management competencies are context sensitive, in order to developing a more targeted approach or target curriculum for the development managers from different sectors, management levels, validation is recommended.