bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multilayer Ultratranslucent Monolithic Zirconia Crowns Treated With Multimode Universal Adhesive System Containing Zirconia Primer: A Clinical Report
Authors: de Miranda Larissa Mendonça , da Silva Sarah Emille Gomes , Santos João Vitor do Nascimento , Souza Rodrigo Othávio de Assunção e 
Published: December 2024

ABSTRACTIntroductionUltratranslucent zirconia combines high mechanical strength and esthetics, making it ideal for monolithic restorations. This case report describes a total rehabilitation of the upper dental arch with single‐unit crowns made of multilayer ultratranslucent zirconia (Prettau 4 Anterior, Zirkonzahn), as well as the use of a simplified adhesive cementation protocol for this type of ceramic.Materials and MethodsA 64‐year‐old female patient sought rehabilitative treatment, after planning in a semi‐adjustable articulator, interim prostheses, from tooth 2 to 15, were installed to restore occlusal vertical dimension and esthetics. After all surgical, periodontal, and endodontic procedures, impressions of the upper and lower arches were taken. In the maxilla, 14 zirconia crowns with a color gradient were fabricated and cemented, with their internal surface treated with a multimode adhesive system containing zirconia primer (Single Bond Universal, 3M ESPE). The same adhesive system was applied to the preparations, and the crowns were cemented with dual resin cement (RelyX Ultimate, 3M ESPE).ResultsAfter the crowns exhibited excellent esthetic results, with only a minor fracture observed on the palatal cusps of the right first upper premolars.ConclusionsThus, ultratranslucent zirconia appears to be a viable option for oral rehabilitation with single‐unit crowns due to its excellent clinical performance.Clinical SignificanceMonolithic ultratranslucent zirconia crowns are able to reproduce the natural characteristics of dental elements. Additionally, the application of 10‐methacryloyloxydecyl dihydrogen phosphate‐based primer has proven to be an efficient surface treatment for adhesive cementation of UT zirconia.
Understanding modifiable barriers to human milk donation in the United Kingdom
Authors: Brown Amy , Jones Sara , Griffiths Catrin , Jones Wendy , Weaver Gillian , Shenker Natalie 
Published: December 2024

AbstractBackgroundWhen premature infants cannot receive their own mother's milk, donor human milk (DHM) is the first‐line recommended option, with growing demand for DHM use outside of neonatal units. To meet the potential need, we need to consider whether DHM supply can increase. This study aimed to explore the reasons that prevent women who wish to donate their milk in the United Kingdom from doing so to understand which barriers may be modifiable.MethodsWomen who wanted to donate their milk but did not do so completed an online survey. Open and closed questions examined the response they received, their reasons for not donating and what they did with any milk that they had already stored.ResultsOut of 732 mothers, 391 (53.4%) did not enquire as they did not think it was possible for them, 218 (29.8%) enquired but were told that they could not donate, 59 (8.1%) enquired but decided not to proceed and 64 (8.7%) received no response. Reasons for being told they could not donate included the use of certain medications, infant age, inadequate staffing, geographic barriers and incorrect storage. Process aspects (e.g., blood tests, practicalities) and lifestyle limitations led mothers to decide not to donate.ConclusionsAlthough some women will be prevented from donating due to medication or health issues, investment in milk banking staffing and infrastructure and awareness campaigns could increase DHM supply, enabling guidelines to extend eligibility criteria for receiving DHM such as for late preterm infants, gestational diabetes or to support low maternal milk supply.
Digit‐in‐Noise Test as a Hearing Screening Test for Individuals With Intellectual Disability
Authors: Shmerler Noa , Fostick Leah , Saban‐Bezalel Ronit 
Published: December 2024

ABSTRACTBackgroundDiagnosis of intellectual disability (ID) may overshadow, or co‐occur with, hearing impairment, but screening is frequently inaccessible due to various factors that prevent successful test execution. There is a pressing need for easily, locally administered hearing tests. This study aimed to assess the efficacy of the digit‐in‐noise (DIN) test, as well as three variations of it, as a hearing screening for individuals with mild to moderate ID. Additionally, we explored correlations between participant characteristics and cognitive‐linguistic abilities, with DIN test performance.MethodForty participants with ID aged 21–40 were recruited from two supported employment centres, 31 of whom met full inclusion criteria. Controls were 20 typically developed (TD) participants, aged 21–40. The original DIN test (DIN(3)) was administered, and those unable to recall the three digits were administered a version with two digits (DIN(2)). Participants unable to successfully complete DIN(3) or DIN(2) were administered versions with added visual and verbal performance feedback.ResultsA significant difference in speech receptive threshold in noise (SRTn) between DIN(2) and DIN(3) was only present for the ID group. A moderate negative relationship between DIN(2) SRTn and vocabulary and a positive relationship with age was found for the ID group; no correlation was found with digit span or matrices. The DIN(2) SRTn was correlated with the average hearing level of pure tones measured by audiometry.ConclusionsOur findings highlight the DIN(2) as the most effective version, as its signal‐to‐noise ratio (SRTn) threshold was closest to the typically developed (TD) control group. This study is the first step towards developing a hearing screening test for individuals with ID who are at elevated risk of impairment and who have insufficient evaluation access. Our findings suggest that adults with mild to moderate ID can sufficiently perform the adapted DIN(2) as a hearing screening test.
Living the popular solidarity economy as an entrepreneurial bureaucrat: Creating and reinforcing ethical frameworks through middle‐class consumption
Authors: D'Aloia Alexander Emile 
Published: December 2024

AbstractThis article examines how middle‐class bureaucrats in Ecuador create and reinforce particular ethical frameworks through their work, their consumption, and their “side hustles.” Having been tasked with growing and strengthening an alternative economy to capitalism, these government functionaries find it important to engage in productive and consumptive practices to help them experience the correct feelings to be able to promote the Popular Solidarity Economy and avoid being disenchanted bureaucrats. Due to the precarious context in which they work, however, these practices are generally reflective of and idealize entrepreneurial logics. I contribute to an expanding literature on the importance of affect to bureaucrats as well as putting that literature in conversation with authors writing about entrepreneurial self‐making. In doing so, I demonstrate how entrepreneurial logics spread into alternative economy space by responding to the very real material and affective needs of government workers in circumstances of precarious employment.
The Macro‐Economic Effects of a European Deposit (Re‐)Insurance Scheme
Authors: CLEMENS MARIUS , GEBAUER STEFAN , KÖNIG TOBIAS 
Published: December 2024

AbstractRecent proposals for a European deposit insurance scheme (EDIS) favor a reinsurance framework. In this paper, we use a regime‐switching open‐economy DSGE model with bank defaults to assess the relative efficiency of such a scheme. We find that reinsurance by EDIS is more effective in stabilizing real activity, credit, and welfare than a national fiscal backstop. We demonstrate that risk‐weighted contributions to EDIS are welfare‐beneficial for depositors and discuss trade‐offs policymakers face during the implementation of EDIS. We also find that macroprudential regulation and EDIS can complement each other and that EDIS can prevent bank runs under certain conditions.
News‐Driven Household Macroeconomic Expectations: Regional vs. National Telecast Information
Authors: GUILLOCHON JUSTINE 
Published: December 2024

AbstractUsing variations in the human‐annotated topic content of national and regional telecasts, I explore the link between aggregated daily news and household unemployment, inflation, and economic situation expectations in France. Beyond the information included in national statistics, household expectations embody news information on topics related to the state of the economy, such as deficit, living cost, and economic crisis. Inflation expectations additionally incorporate news on taxes, energy, and especially oil. Distinguishing regional from national television broadcasts reveals that household expectations incorporate both regional and national news, with news on local labor market conditions having a prominent role.
A land plant‐specific VPS13 mediates polarized vesicle trafficking in germinating pollen
Authors: Tangpranomkorn Surachat , Kimura Yuka , Igarashi Motoko , Ishizuna Fumiko , Kato Yoshinobu , Suzuki Takamasa , Nagae Takuya , Fujii Sota , Takayama Seiji 
Published: December 2024

Summary
Pollen has an extraordinary ability to convert from a dry state to an extremely rapidly growing state. During pollination, pollen receives water and Ca2+ from the contacting pistil, which will be a directional cue for pollen tube germination. The subsequent rapid activation of directional vesicular transport must support the pollen tube growth, but the molecular mechanism leading to this process is largely unknown.
We established a luciferase‐based pollination assay to screen genetic mutants defective in the early stage after pollination. We identified a plant‐specific VPS13, Arabidopsis thaliana VPS13a as important for pollen germination, and studied its molecular function.
AtVPS13a mutation severely affected pollen germination and lipid droplet discharge from the rough endoplasmic reticulum. Cellular accumulation patterns of AtVPS13a and a secretory vesicle marker were synchronized at the polarized site, with a slight delay to the local Ca2+ elevation. We found a brief Ca2+ spike after initiation of pollen hydration, which may be related to the directional cues for pollen tube emergence. Although this Ca2+ dynamics after pollination was unaffected by the absence of AtVPS13a, the mutant suffered reduced cell wall deposition during pollen germination.
AtVPS13a mediates pollen polarization, by regulating proper directional vesicular transport following Ca2+ signaling for directional tube outgrowth.
Climb forest, climb: diverse disperser communities are key to assist plants tracking climate change on altitudinal gradients
Authors: Mendes Sara Beatriz , Nogales Manuel , Vargas Pablo , Olesen Jens M. , Marrero Patrícia , Romero Javier , Rumeu Beatriz , González‐Castro Aarón , Heleno Ruben 
Published: December 2024

Summary
Climate change is forcing species to shift their distribution ranges. Animal seed dispersers might be particularly important in assisting plants tracking suitable climates to higher elevations. However, this role is still poorly understood due to a lack of comprehensive multi‐guild datasets along elevational gradients.
We compiled seed dispersal networks for the five altitudinal vegetation belts of the Tenerife Island (0–3718 m above sea level) to explore how plant and animal species might facilitate the mutual colonisation of uphill habitats under climate change.
The overall network comprised 283 distinct interactions between 73 plant and 27 animal species, with seed dispersers offering viable pathways for plants to colonise upper vegetation belts. A pivotal role is played by a lizard as island‐level hub, while four birds and one introduced mammal (rabbit) are also important connectors between belts. Eleven plant species were empirically found to be actively dispersed to elevations beyond their current known range, with observed vertical dispersal distances largely surpassing those required to escape climate change. Furthermore, over half of the plants arriving at higher elevations were exotic.
Functionally diverse disperser communities are crucial for enabling plants tracking climate change on mountains, but exotic plants might particularly benefit from this upward lift.
Innovative 3D Navigation Module for Precise Unilateral Pedicle Screw Combined with Contralateral Translaminar Facet Screw Placement in Lumbar Spine Surgery
Authors: Chen Xu , Dai Hanhao , Luo Jun , Zhang Huaizhi , Song Chao , Deng Zhibo , Zhang Yanyan , Li Xing , Dai Jianhui , Xu Jie 
Published: December 2024

ObjectiveThe incidence of degenerative diseases of the lumbar spine has increased in recent years. Unilateral pedicle screw combined with contralateral translaminar facet screw fixation offers the advantages of less trauma, better stability, and fewer complications. However, the surgical difficulty and suboptimal pinning accuracy of translaminar facet screw placement in clinical practice limit its use. Therefore, in this study, we designed a novel suspended 3D‐printed navigation module to facilitate fast and accurate intraoperative screw placement. The aim of this study is to investigate the digital design, precise implementation, and evaluation methods for placing unilateral pedicle screws in the lumbar spine combined with translaminar facet screw placement using a new suspended 3D navigation module.MethodsThis retrospective study included 46 patients with single‐level lumbar lesions who underwent spine surgery at the Affiliated Hospital of Putian University between June 2022 and December 2023. The suspended navigation module was designed digitally. Preoperative screw placement was simulated using 3D printed models, followed by an intraoperative accurate screw placement facilitated by the navigation module and a postoperative evaluation of the accuracy of screw placement. The absolute difference in three‐dimensional coordinates of the inlet and outlet points of the preoperative design and the postoperative screw‐nail channel served as the precision index.ResultsIn a study involving 46 patients, surgery was successful with 92 pedicle screws and 46 translaminar facet screws placed without any penetration of the cortex. The difference in coordinates before and after screw insertion was minimal, with entry points varying between 1.21 to 1.36 mm and exit points between 1.97 to 2.46 mm. When screw accuracy met certain thresholds, there was no significant difference between preoperative design and postoperative coordinates, indicating precise replication of the surgical plan.ConclusionThe new suspended 3D navigation module enables the precise placement of unilateral pedicle screws in the lumbar spine combined with translaminar pedicle screws for precise surgery.
Autopsy case of a stillbirth with transient abnormal myelopoiesis associated with Down syndrome: Immunohistochemical demonstration of GATA1 mutation in placental tissues
Authors: Yamazaki Sanae , Miyauchi Jun , Sato Hideaki , Takahashi Yuko , Amikura Takayuki 
Published: December 2024

AbstractTransient abnormal myelopoiesis (TAM) in neonates with Down syndrome (DS) exhibits hematological features that are indistinguishable from those of acute megakaryoblastic leukemia. However, TAM typically resolves spontaneously within several months postnatally. Some patients with TAM, however, develop severe clinical manifestations, which can lead to an unfavorable prognosis. TAM originates in utero through the acquisition of somatic GATA1 mutations, resulting in the loss of the full‐length GATA1 protein and excessive production of the N‐terminal truncated short isoform of the GATA1 protein (GATA1s). Herein, we report the pathological findings from an autopsy of a female stillbirth with TAM and DS, including an examination of her placental tissues. Immunohistochemical analysis revealed the expression of GATA1s, but not full‐length GATA1, in CD42b‐positive atypical immature megakaryocytes and blasts in the placental blood vessels. This confirms the diagnosis of TAM and suggests the utility of placental tissue for histological diagnosis. Additional unique findings from the autopsy specimens are discussed.
Integrated Community‐Based Reporting and Field Diagnostics for Improved Rabies Surveillance in Rural Laikipia, Kenya
Authors: Odinga Christian O. , Thomas Lian F. , Wambugu Evalyne , Ferguson Adam W. , Fèvre Eric M. , Gibson Andy , Hassell James M. , Muloi Dishon M. , Murray Suzan , Surmat Andrea , Mwai Peter M. , Woodroffe Rosie , Ngatia Dedan , Gathura Peter M. , Waitumbi John , Worsley‐Tonks Katherine E. L. 
Published: December 2024

ABSTRACTRabies vaccination in domestic dog populations has increased globally in a bid to protect human health. Surveillance efforts, however, are inconsistent in endemic regions such as in sub‐Saharan Africa, due to fragmented reporting and limited diagnostic capacity for suspected cases, limiting successful monitoring and evaluation of vaccination campaigns. Here, we conducted a pilot study aiming to strengthen rabies surveillance by combining community‐based surveillance with field‐based diagnostic testing in pastoral and agro‐pastoral communities in central Kenya; communities which are frequently marginalised from health systems. During the 6‐month pilot study, there were 14 alerts of suspected rabid dogs in the community, of which eight were tested and five diagnostically confirmed as rabid. Two positive samples processed successfully for whole genome sequencing indicated that the rabies variant circulating in central Kenya during the study period belonged to the Africa 1b subclade, which is similar to variants identified in eastern Kenya and Tanzania, suggesting regional transmission. This pilot study indicates that rabies continues to circulate in the region and that community‐based surveillance, when combined with enhanced diagnostic testing, can help alleviate underreporting and guide vaccination campaigns.
A CFD-FEA Co-Simulation Study of Thermal Barrier Coatings for Gasoline Compression Ignition
Authors: Gainey Brian , Koirala Prakash , Sellnau Mark , Filipi Zoran , Lawler Benjamin 
Published: December 2024

Abstract
Thermal barrier coatings (TBCs) applied to combustion chamber surfaces aim to increase engine efficiency by reducing heat transfer via elevated surface temperatures during combustion. This work presents a computational study of TBCs in the partially premixed compression ignition-diffusion concept of gasoline compression ignition (GCI) using a computational fluid dynamics (CFD)-finite element analysis (FEA) co-simulation. The in-cylinder processes are simulated in CFD and the predicted heat flux is passed to FEA to resolve the spatially and temporally varying surface temperature profile of the TBC-coated engine parts. This surface temperature profile is subsequently passed back to CFD in an iterative process until convergence is achieved. The results indicate that performing a CFD-FEA co-simulation is critical to accurately predict the heat transfer, and by extension the efficiency, of an engine cycle operating in a mixing controlled mode of combustion compared to using an assumed constant piston temperature. Even an uncoated metal piston displays significant spatial variation of the piston surface temperature as well as the heat flux. The results also indicate that the 250 micron Gadolinium Zirconate Oxide (GZO) coating experienced an average temperature swing of &gt; 100 K at 10 bar IMEPn, while high heat flux areas under the plume experienced a local temperature swing of up to 300 K. This led to an efficiency improvement of ∼0.4 percentage points, agreeing with experiments. When the simulation was performed at 15 bar IMEPn, a substantial efficiency benefit of 1.4 percentage points was observed, while the experimental results indicated a slight indicated efficiency penalty. The only apparent explanation of this discrepancy is the occurrence of a convection vive effect, which is not captured by the CFD simulation. Small combustion chamber height in a light-duty engine exacerbates the effect, due to the close proximity of the burning jet to the piston and head surfaces throughout combustion.
Experimental Investigation of Particulate Emissions From An Ammonia-Fueled Internal Combustion Engine
Authors: Patil Tejashri , Reggeti Shawn , Kane Seamus P. , Northrop William F. 
Published: December 2024

Abstract
Ammonia combustion is a topic of active research due to the need for fuel decarbonization. Although ammonia does not contain carbon, its use in internal combustion (IC) engines may still form nitrogen-containing ultrafine particulate matter. This work investigates particulate emissions from NH3-H2-air combustion in a single-cylinder Waukesha Cooperative Fuel Research (CFR) octane engine under a range of hydrogen blending and engine load. Particle size distributions were quantified using a Scanning Mobility Particle Sizer (SMPS). A dual-stage dilution sampling system was used to reduce unburned ammonia concentration and maintain particle concentration within the instrument limits. The engine was motored to measure crankcase particle emissions from lubricant oil atomization. Additionally, 100% hydrogen-fueled experiments were conducted to evaluate the effect of combustion on particulate emissions from lubricant oil atomization without NH3-based particulate formation. Various ammonia-hydrogen fuel blends were tested to quantify the contribution of ammonia-based particulate matter in the exhaust. The elevated particle number concentration as the ammonia fraction rises suggests that combustion with ammonia leads to higher particulate emissions compared to hydrogen combustion at the equivalent peak in-cylinder pressure. Additionally, the presence of both unburned ammonia and NO2 in the exhaust indicate that the measured particles may consist of ammonium nitrate based on known chemical mechanisms. Modeling suggests that NH3 and NO2 found in cold regions of the combustion chamber have the potential to form gas-phase ammonium nitrate that later condenses to form particles in the exhaust system.