bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meningkatkan Keterampilan Kader Kesehatan dalam Melakukan Pemeriksaan Payudara Sendiri (SADARI)
Authors: Lina Wiraswati Hesti , Ekawardhani Savira , Windria Sarasati , Faridah Lia 
Published: July 2019

<p class="05-ABSTRACTbody"><span lang="EN-US">Breast cancer is one of the most common cancer types suffered by women in the world. In 2018, the International Agency for Research on Cancer (IARC) estimated number of cancer cases in Indonesia was 42.1 per 100000 females, while the death rate was 17 per 100000 females. These conditions are worrisome and call for serious handling. For this purpose, the effectiveness of patient treatment and life quality must be improved. Therefore, this study aims to improve the knowledge and skills of breast cancer early detection. The method used is health training through audio-visual devices and demonstration. Qualitative and quantitative analysis was carried out using paired t-test. The s</span><span lang="EN-US">ampling data was acquired by purposive sampling method using a questionnaire. The result showed that first, majority of health cadres (97%) had less knowledge about BSE, before the training was carrying out. Second, lack of knowledge about BSE apparently did not prevent health cadres from doing BSE (28%). Third, BSE training improves the skills of health cadres with an average increase of 31%. Fourth, the training has also increased the knowledge of all cadres about BSE with an average increase of 29%. In addition, all cadres stated that they would disseminate their BSE knowledge and skills to their families and others.</span></p><p class="05-ABSTRACTbody"> </p><p class="05-ABSTRACTbody"><em>Kanker payudara merupakan salah satu jenis kanker yang paling banyak di derita oleh wanita di dunia. International Agency for Reseach on Cancer (IARC) pada tahun 2018 memperkirakan insiden kanker payudara di Indonesia sebesar 42.1 per 100 ribu wanita, sedangkan angka kematiannya sebesar 17 per 100 ribu penduduk. Situasi seperti ini sangat mengkhawatirkan dan perlu penanganan serius dari berbagai pihak. Dengan demikian penelitian ini bertujuan untuk meningkatkan keterampilan kader kesehatan dalam melakukan pemeriksaan payudara sendiri (SADARI). Metode yang dilakukan adalah dengan melakukan pelatihan melalui perangkat audio visual dan alat peraga. Analisis kualitatif dan kuantitatif dilakukan menggunakan uji t-test berpasangan. Pengambilan sampel dilakukan secara purposive sampling dengan cara penetapan besar sampel berdasarkan jumlah kebutuhan minimal dengan menggunakan kuesioner. Hasil penelitian ini menunjukkan bahwa pertama, mayoritas kader kesehatan memiliki pengetahuan kurang tentang SADARI (97%). Kedua, pengetahuan yang kurang tentang SADARI rupanya tidak menghalangi kader kesehatan untuk melakukan SADARI (28%). Ketiga, pelatihan SADARI meningkatkan keterampilan kader kesehatan dengan rata-rata peningkatan 31%. Keempat, pelatihan SADARI juga meningkatkan pengetahuan kader dengan rata-rata peningkatan 29%. Disamping itu, semua kader menyatakan bahwa mereka akan menyebarkan pengetahuan dan keterampilan SADARI yang mereka miliki kepada keluarga dan orang lain</em></p>
Peningkatan Kualitas Tidur Klien Kardiovaskuler dengan Pengaturan Posisi Tidur
Authors: Merdekawati Diah , Susanti Farida , Maulani Maulani 
Published: July 2019

<p><em>The quality of sleep was someone’s satisfying feel for sleep, which made that person didn’t show any kind of tiredness, restlessness, worn out, apathy and constant yawning or sleepiness. One of the methods that could be done to overcome the bad quality of sleep was the giving of sleeping position. The aim of the giving of sleeping position was to lower oxygen consumption and increasing lungs expansion to maximal. The kind of this study was quasi experiment with one group pre-test and post-test design. The samples of this study were 33 respondents who had the match criteria in this study. The samples were taken with accidental sampling technique which the case or the respondents were taken by accident or available at that time. Analysis of the data in this study was done with Univariate and Bivariate. This study was using questioner as a helper in collecting data. The result of statistic test was p-value rate= 0,000 which meant there was significantly difference the estimate respondent’s quality of sleep before and after treatment. It could be concluded that there was an influence of the setting of sleeping position upon the quality of sleep for the clients at Cardio Ward. It was expected that the regional hospital's RadenMattaher Jambi could make this sleeping position 45<sup>o</sup> arrangement into an intervention and equality of positions on each of the clients</em></p><p> </p><p><em>Kualitas tidur adalah kepuasan seseorang terhadap tidur, sehingga seseorang tersebut tidak memperlihatkan perasaan lelah, gelisah, lesu, dan sering menguap atau mengantuk. Salah satu cara yang dapat dilakukan untuk mengatasi adalah dengan pemberian posisi tidur. Tujuan tindakan memberikan posisi tidur adalah untuk menurunkan konsumsi oksigen dan meningkatkan ekspansi paru yang maksimal. Jenis penelitian ini adalah penelitian quasi eksprimen dengan desain one group pre-tes post-test. Sampel dalam penelitian ini 33 responden yang memiliki kriteria sesuai dengan yang akan diteliti. Teknik pengambilan sampel dilakukan dengan cara accidental sampling yaitu pengambilan sampel dilakukan dengan mengambil kasus atau responden yang kebetulan ada atau tersedia. Analisa data dalam penelitian ini secarra Univariat dan Bivariat. Penelitian ini menggunakan kuesioner sebagai alat bantu dalam pengumpulan data. Hasil uji statistic diperoleh nilai p-value = 0,000 artinya terdapat perbedaan signifikan nilai kualitas tidur responden sebelum dan sesudah perlakuan. Dapat disimpulkan bahwa terdapat pengaruh pengaturan posisi tidur terhadap kualitas tidur pada klien di ruang rawat inap jantung. Diharapkan kepada pihak RSUD Raden Mattaher Jambi dapat menjadikan pengaturan posisi tidur 45<sup>o</sup> ini menjadi intervensi dan kesetaraan posisi pada setiap klien</em></p>
Pengetahuan Remaja Putri Tentang Konsumsi Tablet FE Pada Saat Menstruasi Pengan Anemia
Authors: Angrainy Rizka , Fitri Lidia , Wulandari Vipit 
Published: July 2019

<p><em><em><em>Anemia is a public health problem in the world. According to the World Health Organization (WHO), anemia cases occur 24.8% of the population and an estimated 50-80% of anemia is caused by iron deficiency. Anemia most often occurs in adolescents during menstruation and can be prevented by consuming Fe tablets. Initial survey of 10 female students showed most do not know about consuming Fe tablets during menstruation and 3 of them have Hb below 12 g%. The purpose of research to know the relationship of the adolescent knowledge about consuming fe tablets when menstrual with anemia in Junior High School 20 Pekanbaru 2018. The research design is quantitative Analitic with Cross Sectional approach.The population in this research amounted to 148 people with sampling using technique is purposive sampling as many as 86 people. The data obtained from the questionnaire and Hb measurements on the respondents.The statistical analysis used chi-square. The result of univariate analysis showed that most of the respondents (59,3%) had good knowledge about consuming Fe tablets during menstruation and the majority of respondents (84,3%) is not anemic. Test result obtained P Value &lt; α (0,001&lt;0,05), and it can be concluded that there is a significant relationship between of the adolescent knowledge about consuming Fe tablets when menstrual with anemia.</em></em></em></p><p><em><br /></em></p><p><em>Anemia merupakan masalah kesehatan masyarakat diseluruh dunia. Menurut World Health Organization (WHO), kasus anemia terjadi 24,8% dari populasi dan diperkirakan sekitar 50-80% anemia disebabkan oleh defisiensi besi. Anemia paling sering terjadi pada remaja saat menstruasi dan dapat dicegah dengan mengonsumsi tablet Fe. Survei awal terhadap 10 siswi menunjukkan sebagian besar tidak mengetahui tentang konsumsi tablet Fe pada saat menstruasi dan 3 diantaranya memiliki Hb dibawah 12 gr%. Tujuan penelitian untuk mengetahui hubungan pengetahuan remaja putri tentang konsumsi tablet Fe pada saat menstruasi dengan anemia di SMP Negeri 20 Pekanbaru. Jenis penelitian Analitik Kuantitatif dengan desain Cross Sectional. Populasi sebanyak 148 orang dengan pengambilan sampel menggunakan purposive sampling sebanyak 86 orang. Data penelitian diperoleh dari kuesioner dan pengukuran Hb. Analisa data menggunakan uji chi-square. Hasil penelitian sebagian besar responden 59,3% memiliki pengetahuan baik tentang mengonsumsi tablet Fe pada saat menstruasi dan mayoritas responden 84,3% tidak anemia. Hasil uji diperoleh Pvalue &lt; α (0,001&lt;0,05) dan dapat disimpulkan bahwa ada hubungan yang bermakna antara pengetahuan remaja putri tentang konsumsi tablet Fe pada saat menstruasi dengan anemia.</em></p>
Pengaruh Kepuasan Kerja dan Stres Kerja terhadap Turnover Intention pada PT Bank OCBC NISP Tbk Area Jakarta Pusat
Authors: Hakim Arief Rachman , Sugiharjo Raden Joko 
Published: July 2019

ABSTRACT This study to determine the effect of Job Satisfaction and Job Stress on Turnover Intention. The object of this research is PT Bank OCBC NISP Tbk Central Jakarta Area. This research is a causal associative research using quantitative approach done to 86 respondents. This study explains the influence and influence of the variables to be studied, using multiple linear regression analysis method. From the results of this study showed that the variable of Job Satisfaction Not Significant To Turnover Intention. While the variable of Work Stress has significant effect to Turnover Intention. Keywords : Organizational Culture, Training Program, Compensation, Employee Loyalty
Effect of Moulding Pressure on Brake Lining Produced from Industrial Waste Material: Sawdust
Authors: Oladokun Taiwo Oseni , Stephen Joseph Temitope , Adebayo Adeyinka , Adeyemi Gbenga Joshua 
Published: July 2019

In this study, asbestos-free brake lining was developed with sawdust. Sawdust was considered an alternative to asbestos, whose dust is carcinogenic. The sawdust from hard wood (mahogany and iroko trees) and other components such as abrasive, reinforcer, lubricant, were sieved into grade of 100 µm and used in production of brake linings. The percentages of sawdust for the samples are 40, 45, 50, 55, and 60. The percentages of abrasives (silicon carbides) were 27, 22, 17, 12 and 7, while binder (resins) lubricant (steel dust) and carbon black (reinforcer) were constant at 13%, 15% and 5% respectively on each sample. The molding pressure load was varied at 10 Mg, 20 Mg, 40 Mg, 60 Mg and 80 Mg during compression process. The brake lining properties examined are hardness, compressive strength and density. Also, the effects of molding pressure on these properties were evaluated. The results obtained show that the higher the molding pressure, the better the physical and mechanical properties. Furthermore, at high molding pressure, the properties reached a limiting point which they tend to be constant. The brake linings based on sawdust were then compared with commercial (asbestos-based) brake lining and the results are in close agreement. Hence, sawdust can be effectively used as filler for replacement of asbestos in brake linings.
أغراض الإستفهام بـ "هل" فى الذكر الحكيم
Authors: Nawawi Aksa Muhammad 
Published: July 2019

هذا البحث يتحدث عن الاستفهام بــ"هل" فى الذكر الحكيم, يتضمن مبحثين, أما الأول: كيف كانت حقيقة "هل " فى اللغة العربية؟ والثاني: كيف كانت أغراضه فى علم البلاغة وفى الذكر الحكيم؟ فالبحث جار على التحليل البلاغي الكيفي, وتجري على دراسة كتب, ويعنى بها أن المعلومات –بجانب المعلومات التى صدرت من تحليل الكاتب - صادرة من المصادر ا لمكتوبة– وهى الكتب – التى تتعلق بموضوع البحث. والمنهج المستخدم أو الطريقة المستخدمة فى البحث هو علوم البلاغة والسياق والمناسبة والنحو والتركيب والتفسير. فالكاتب جعل "هل" فى الذكر الحكيم مادة أولى بالمساعدة على الكتب المتعلقة به لمعرفة الأغراض والأسرار. فالذي يدفعني إلى اختيار هذا الموضوع هو غموض هذا الموضوع. فقد نرى - بنظرة ساطحة - كثيرا فى القران استخدام هذا الأسلوب. فلذلك يحتاج هذا الأسلوب إلى دراسة لفك الغموض وكشف الأسرار. ونتيجة البحث تدل على أسرار ومعاني بلاغية دقيقة لهذا الأسلوب, وأنها تنقسم إلى قسمين: معان رئيسية ومعان فرعية . فالمعاني الرئيسية تنحصرعلى معان أربعة : تقريري, وإنكاري, وطلبي, وعرضي. أما المعاني الفرعية فهي لاتنحصرمنها: التوبيخ والتعجيز والتهكم إلى غير ذلك من المعاني تستنبط من السياق.
Market Research Concerning Functional and Material Solutions Employed in Nursery Facilities
Authors: Radziszewska-Zielina E. , Grabowska W. , Szewczyk B. 
Published: July 2019

AbstractA great number of non-functional child care facilities for children up to the age of three have been created in Poland to this day. This state of affairs may be the consequence of the low level of knowledge in this field, as well as few available studies on topics associated with nursery facilities, which may familiarise readers with the legal aspects, administrative procedures, or examples of good functional and material solutions of such units. What is more, there is also little information about the needs and preferences of people directly related to the topic. The aim of the article is to analyse the expectations and preferences of nursery facilities’ users in terms of the functional and material solutions. Based on a survey conducted among the nurseries’ employees and parents placing their children in the care of such institutions, a number of guidelines has been defined, allowing for the design of an optimal nursery facility that would meet the market’s expectations.
Optical Coherence Tomography-Angiography of Different Choroidal Neovascularization Subtypes in Wet Age-related Macular Degeneration
Authors: Stavrev Vladimir N. , Sivkova Nelly P. , Koleva-Georgieva Desislava N. 
Published: July 2019

Abstract
Age-related macular degeneration is a leading cause of irreversible vision loss in individuals over 55 years of age worldwide. Conventionally, it is divided into two subtypes – dry (non-neovascular) and wet (neovascular) form. Neovascular age-related macular degeneration comprises only 10-15% of all patients but is responsible for more than 80% of blindness related to the disease. It requires early diagnosis and timely treatment. Fluorescein angiography is the current ‘gold standard’ for diagnosing neovascular forms. However, as an invasive procedure, it may be contraindicated in some circumstances and cause serious adverse effects. Optical coherence tomography-angiography is a relatively new, non-invasive and fast imaging modality gaining popularity in the diagnosis of age-related macular degeneration, especially for the neovascular form of the disease. It enables structural and functional information of blood vessels in the retina and choroid, without the need of an intravenous dye. In this study we present and discuss 3 cases of different subtypes of choroidal neovascularization secondary to neovascular age-related macular degeneration. All of them were examined by fluorescein angiography and optical coherence tomography-angiography. The results were qualitatively analyzed.
Role of Fecal Calprotectin as a Noninvasive Indicator for Ulcerative Colitis Disease Activity
Authors: Nakov Radislav V. , Nakov Ventsislav N. , Gerova Vanya A. , Tankova Lyudmila T. 
Published: July 2019

Abstract
Background: It is essential in clinical management to determine the disease activity in ulcerative colitis (UC) patients. At present, the most accurate way of evaluating the UC severity is endoscopy with biopsy. Fecal calprotectin (FCP) is a non-invasive biomarker that is frequently used for monitoring of intestinal inflammation.
Aims: The purpose of our study was to assess the role of FCP as a noninvasive indicator for UC disease activity.
Materials and methods: This prospective study enrolled 116 patients with UC (56 with quiescent UC and 60 with active UC) and 36 controls, referred for colonoscopy to our Center. Colonoscopy was performed in all the patients and the findings were graded according to Mayo endoscopic score (EMS) and UC endoscopic index of severity (UCEIS). FCP was analyzed in stool samples by means of point-of-care desk-top Quantum Blue® method.
Results: There was no significant difference between mean FCP levels in controls and UC patients in remission (р=0.205). Mean FCP in patients with active UC was significantly higher than that in controls (p<0.001) and in patients in remission (p<0.001). FCP significantly correlated with UCEIS (r = 0.869, p<0.001) and EMS (r = 0.814, p<0.001).
Conclusion: The strong correlation with endoscopic disease activity suggests that FCP is a useful biomarker for noninvasive diagnosis and monitoring of disease activity in UC patients.
Temperature-dependent in Situ Gel of Clotrimazole: an Experimental Study
Authors: Patel Vipul P. , Damasiya Harshad M. , Kapupara Pankaj , Ashara Kalpesh C. 
Published: July 2019

Abstract
Background: The in-situ gel-forming polymeric formulations offer sustained and prolonged action in comparison to conventional drug delivery systems.
Aim: To formulate and evaluate in situ vaginal gel of clotrimazole.
Materials and methods: Poloxamer 407 (20%) was slowly added to freezing water (5°C) with constant stirring. The prepared dispersion was refrigerated for 5 h, the different concentrations of polymers were added for preliminary batches. Differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR) were performed for clotrimazole-excipients compatibility study. The final batch was prepared and evaluated for physicochemical parameters, in vitro clotrimazole release, in vitro antifungal activity, and in vivo vaginal tissue irritation test.
Results: The compatibility study showed no chemical interaction between clotrimazole and excipients used. The evaluation parameters showed that clotrimazole release was in the range of 8 to 10 h, gelling temperature was in the range of 27–35°C, gelling time was in the range of 28–34 sec, pH was in the range of 4.4–4.8, and viscosities were in the range of 16.4–182.6 cP (solution form) and 10,500–20,756 cP (gel form). The zone of inhibitions for clotrimazole pure drug, the marketed vaginal gel of clotrimazole, and optimized gel formulation was 9.15±0.75 mm, 14.35±1.12 mm, and 18.85±1.56 mm, respectively (p < 0.0001, q = 5.98). An optimized gel formulation was not irritant to vaginal tissue.
Conclusion: It was possible to formulate effective in situ vaginal gel for control release action of clotrimazole.
Level of Evidence: IIC.
The Epithelial-Mesenchymal Transition, E-cadherin and Tumor Progression in Ovarian Serous Tumors
Authors: Bozhkova Desislava M. , Poryazova-Markova Elena G. 
Published: July 2019

Abstract
Background: The epithelial-mesenchymal transition (EMT), which is a change in the cell phenotype from epithelial to mesenchymal morphology, is an important step in the invasion process and metastasis of ovarian carcinomas. It is known that the suppression of cell adhesion molecules such as E-cadherin and the expression of mesenchymal markers such as Vimentin are key processes in EMT. There is controversy in the literature about the EMT status of ovarian carcinomas.
Aim: To investigate EMT status using immunohistochemical expression of E-cadherin in benign, primary malignant serous ovarian tumors and metastases from them in order to assess their significance in tumor progression.
Materials and methods: The study included a retrospective investigation of 217 ovarian epithelial tumors. Ninety-two cases of serous ovarian tumors and metastases were examined for expression of E-cadherin.
Results: In our study, the predominant histological subtype in benign ovarian tumors and carcinomas was serous (73% and 61%, respectively). 65% of benign tumors demonstrated EMT negative status. The majority of carcinomas demonstrated EMT positive status (82%), whereas negative EMT status was only observed in 18% of cases. 89% of the metastases showed EMT positive status, whereas only 11% of them showed negative EMT status. In 6 selected cases with positive EMT status we found Vimentin expression in tumor cells.
Conclusion: Positive EMT status (reduced E-cadherin expression) is a characteristic of ovarian carcinomas and metastases, but not of benign serous ovarian tumors.
NPS2390, a selective calcium-sensing receptor antagonist controls the phenotypic modulation of hypoxic human pulmonary arterial smooth muscle cells by regulating autophagy
Authors: Peng Xue , Wei Can , Li Hong-Zhu , Li Hong-Xia , Bai Shu-Zhi , Wang Li-Na , Xi Yu-Hui , Yan Jin , Xu Chang-Qing 
Published: July 2019

Abstract

Background and Objectives
Calcium-sensing receptor (CaSR) is known to regulate hypoxia-induced pulmonary hypertension (HPH) and vascular remodeling via the phenotypic modulation of pulmonary arterial smooth muscle cells (PASMCs) in small pulmonary arteries. Moreover, autophagy is an essential modulator of VSMC phenotype. But it is not clear whether CaSR can regulate autophagy involving the phenotypic modulation under hypoxia.

Methods
The viability of human PASMCs was detected by cell cycle and BrdU. The expressions of proliferation protein, phenotypic marker protein, and autophagy protein in human PASMCs were determined by western blot.

Results
Our results showed that hypoxia-induced autophagy was considerable at 24 h. The addition of NPS2390 decreased the expression of autophagy protein and synthetic phenotype marker protein osteopontin and increased the expression of contractile phenotype marker protein SMA-ɑ and calponin via suppressing downstream PI3K/Akt/mTOR signal pathways.

Conclusions
Our study demonstrates that treatment of NPS2390 was conducive to inhibit the proliferation and reverse phenotypic modulation of PASMCs by regulating autophagy levels.
Unknown use of end-tidal CO2 in metabolic emergencies in pediatric patients
Authors: Redant Sebastien , Angoulvant Francois , Honore Patrick M. , Attou Rachid , Biarent Dominique , Bels David De 
Published: July 2019

Abstract
The authors describe two cases of metabolic acidosis, caused by diabetic ketoacidosis in the first case and by dehydration following gastroenteritis in the second one. Both patients were followed with noninvasive end-tidal CO2 (ETCO2) monitoring. A correlation between EtCO2 and PCO2 and HCO3− has been established in the literature. Noninvasive ETCO2 is used in only 5–6% of metabolic emergencies. In contrast, users described its use as easy and convenient.
Magnetostrictive Vibration Model for Evaluation of Mechanical Integrity of Power Transformer Magnetic Core
Authors: Marks J. , Vitolina S. , Dirba J. 
Published: July 2019

Abstract
Magnetostriction process creates vibrations within magnetic core of a power transformer. This effect can cause delamination of magnetic core layers and increase the vibration amplitudes on the surface of transformer tank. In this paper, a magnetostrictive vibration model is proposed for improved evaluation of the mechanical integrity of magnetic core and the finding of possible mechanical defects. This model is based on the simulation of magnetostrictive vibrations by replacing the magnetic core with mass and spring system, and application of a dynamic genetic algorithm in order to find the necessary system configuration. A case study is provided structurally modelling magnetic core in Matlab and Matlab Simulink with the analysis of simulated vibrations that indicate a possible mechanical defect.