bluuebunny/crossref_metadata_2025_split huggingface dataset:
BAROREFLEX AND ADAPTATION OF VISCERAL SYSTEMS IN RENOVASCULAR HYPERTENSION
Authors: Tsyrlin V. A. , Kuzmenko N. V. , Pliss M. G. , Rubanova N. S. 
Published: December 2018

Objective. To test the hypothesis, that the arterial baroreceptor reﬂ ex plays the key role for the phenomenon of visceral systems adaptation for long-term afferent drive. Design and methods. In Wistar rats the model of the «two kidneys, one clip» vasorenal hypertension was carried out. The sino-aortic denervation was performed in one group — before the left renal artery clipping, in the other group — 8 weeks after the left renal artery clipping. Results. The renal artery clipping led to the increase of blood pressure only in 17 % of animals with intact sino-carotid-aortic mechanoreceptor zones. The absence of hypertension in these animals might be due to the cardiovascular adaptation phenomenon to prolonged afferent action from ischemic kidney. Denervation of mechanoreceptor zones before the clipping of the renal artery contributes to the development of hypertension in 100 %. However, the denervation of sino-carotid and aortic zones performed 8 weeks after the renal artery clipping in rats without hypertension, does not affect blood pressure level.Conclusion. We suggest, that the absence of hypertension after renal artery clipping is due to the adaptation of the circulatory system to a long-term afferentation from the kidney, and the denervation of large vessels mechanoreceptor zones does not alter this process. At the same time, the damage of the arterial baroreceptor reﬂ ex before renal artery clipping interferes in the visceral systems adaptation to afferent action and contributes to the arterial hypertension development.
MAGNETIC RESONANCE SPECTROSCOPY IN EVALUATION OF COGNITIVE FUNCTIONS IN PATIENTS WITH METABOLIC SYNDROME
Authors: Zueva I. B. , Moroshkina N. V. , Barantsevich E. R. , Trufanov G. E. 
Published: December 2018

Objective. To evaluate the role of magnetic resonance spectroscopy (MR-spectroscopy) in the study of cognitive functions in patients with metabolic syndrome (MS).Design and methods. The study included patients with MS (10 patients without cognitive impairment and 11 subjects with cognitive dysfunction). All patients underwent neuropsychological testing, and cognitive evoked potential for the assessment of cognitive functions. Brain metabolism was studied by proton MR-spectroscopy.Results. In patients with MS and cognitive impairment, and without cognitive dysfunction no morphological changes in the brain according to the magnetic resonance imaging (MRI) were found. According to MR-spectroscopy of the brain in patients with MS and cognitive dysfunction the metabolism impairment is primarily associated with the increase in lactate and inositol.Conclusion. Indicators of neuropsychological testing, the cognitive evoked potential are associated with the violation of brain metabolism in patients with MS and cognitive impairment.
INFORMATION AND DIGITAL TECHNOLOGIES IN PREVENTION OF HYPERTENSION
Authors: Kostin A. V. , Kostina S. A. 
Published: December 2018

Objective. To determine the criteria for the application of preventive measures for individual computer program «Medical and psychological prevention of complications, and the normalization of physiological parameters in a hypertensive patient».Design and methods. With the ﬁnancial support of the Government of the Russian Federation, the State contract № 6464r/9021 of 28.12.2008, we have developed and registered in the Federal Institute of Industrial Property preventive medical computer program «Medical and psychological prevention of complications, and the normalization of physiological parameters in a hypertensive patient» № 2011618469, state registration number 01200951860. We examined 180 patients (120 hypertensives and 60 controls) aged 20–70 years (mean age 35,5 ± 7,2 years), patients of the main group had a primary diagnosis of hypertension (I, II, III degree). We performed clinical neurological, standard laboratory and instrumental diagnostic examinations and psychodiagnostic testing, as well as the pulse measurements by cardiointervalography followed by mathematical analysis of the data by a special program.Results. Analysis of reactions in the interim period of adaptation (14–21 day) has shown its important role to predict the outcome of preventive measures. According to our data 88,2 % patients with hypertension III degree and 94,4 % patients with hypertension II degree demonstrated normalization of the blood pressure and improvement in general state, and the approach was beneﬁcial in 100 % patients with hypertension I degree. Mean recovery time after hypertensive crisis was 15,0 ± 5,0 minutes in patients with hypertension I degree, 30,0 ± 10,0 minutes in patients with hypertension II degree (p < 0,001), and 45,1 ± 27,4 minutes in patients with III degree (p < 0,05). Patients, who used personal computer software, demonstrated the reduction of irritability, fatigue, improved sleep, memory, increased work efﬁiency, disappearance of sleepiness, and there was an increase in self-conﬁdence.Conclusions. Thus, our results show that the use of individual computer program «B/P rate» leads to the reduction of the frequency and duration of hypertensive crises, as well as to the improvement of cognitive function and psychosocial parameters.
ARTERIAL HYPERTENSION PREVALENCE IN MOSCOW IN DIFFERENT TIME INTERVALS
Authors: Balanova Y. A. , Shalnova S. A. , Deev A. D. , Konstantinov V. V. , Kapustina A. V. 
Published: December 2018

Objective.To assess population mean blood pressure (BP), prevalence, treatment, and control of arterial hypertension from 1975 to 2001 depending on the socio-demographic indicatorsDesign and methods.Seven independent cross-sectional population surveys were conducted in 1975–2001 with randomly selected men (10094) and women (3527) aged 25–64 years old,Moscow residents, with response > 70 %. We have combined data from studies performed in Soviet period, «the period of perestroika» and post-Soviet period.Results.Systolic BP (SBP) has increased from «Soviet period» to «the period of perestroika» in men by 2,5 mmHg (р < 0,05), and in women by 5 mmHg (р < 0,001). Diastolic BP (DBP) has increased among men (from 87,0 to 87,8 mmHg, р < 0,02), and among women (from 81,5 to 87,2 mmHg, р < 0,001). In the late 90’s SBP has decreased (in women from 137,5 to 130,1 mmHg, р < 0,02), DBP has decreased (in men — to 85,1 mmHg, р < 0,02, and in women — to 81,3 mmHg, р < 0,005). There was a statistically signifi cant increase in the prevalence of arterial hypertension from «Soviet period» to «the period of perestroika» (from 46,5 to 49,2 % in men; from 38,7 to 50,3 % in women, р < 0,001). In the post-Soviet period it has decreased among men to 39,8 % and among women to 32,7 % (р < 0,04). The rate of adherence to antihypertensive medications has increased (in men from 6,2 to 19,4 %, р < 0,001; and in women from 15,5 to 26,6 %, р < 0,001). The proportion of effectively treated hypertension has decreased (in men from 35,7 to 23,4 %, and in women from 36,9 to 31,7 %). Control of hypertension improved signifi cantly from 3,6 to 5,8 % (р < 0,01).Conclusion.The prevalence of arterial hypertension remains high. The main objective of physicians is to increase the number of effectively treated patients and to achieve target levels of blood pressure.
THE TIMING OF PUBERTY: WELL-KNOWN AND NEW ISSUES
Authors: Nikitina I. L. 
Published: December 2018

Puberty is an important developmental milestone. It can be considered as a complex sequence of biological events leading to progressive maturation of sexual characteristics ultimately leading to attainment of full reproductive capacity. The decline in age at puberty in the general population has been paralleled by an increase in the number of girls referred for evaluation of precocious puberty (PP). The recent pubertal trends have resulted in a concomitant lowering of the lower limit of normality of the pubertal onset. However, evidence suggests that age at the gonadotropin and sex steroid surges have not changed. Thus, it looks as if an increasing proportion of contemporary early pubertal girls may experience isolated gonadotropinindependent thelarche rather than central PP, which may not be discernible on pubertal examination alone. Thus, the population-based limits of normality srapid progressive PP as well as intracranial and other underlying pathology. The initiation of mammalian puberty requires an increased pulsatile release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. This increase is brought about by changes in transsynaptic and glial-neuronal communication. Coordination of these cellular interactions likely requires the participation of sets of genes hierarchically arranged within functionally connected networks. The role of kisspeptins in the control of GnRH neurons and the transmission of the regulatory actions of key signals, such as sex steroids, metabolic hormones and environmental cues, has been recently studied, point out that the Kiss1 system is an indispensable player of the brain sexual differentiation during early periods of maturation and the timing of puberty onset.
CIRCADIAN BLOOD PRESSURE PROFILE IN YOUNG SUBJECTS WITH PRE-HYPERTENSION
Authors: Evsevyeva M. E. , Mishchenko E. A. , Rostovtseva M. V. , Galkova I. Y. , Chudnovsky E. V. , Rusidi A. V. , Smirnova T. A. , Ivanova L. V. 
Published: December 2018

and arterial hypertension for the planning of timely and effective prevention. Design and methods.We enrolled 147 people: with optimal and normal BP — 81, with high normal BP — 30 men, and 36 controls. Ambulatory BP monitoring (ABPM) nas performed in the offi ce at the setting of ≪typical working day≫ or 24 +- 1,5 hours with 15 and 30 minute intervals between the measurements during the day and night, respectively.Results.Young people with high normal BP differ from the subjects with normal and optimal BP by a variety of ABPM indices. However, the changes are lower, but similar to those observed in patients with evident hypertension, including increase of mean systolic and diastolic BP, time index of systolic and diastolic BP, and morning BP surge. Young men with high normal BP are also characterized by the family history of the early cardiovascular disease and the presence of cardiocerebral complaints with the frequency similar to that in hypertensive subjects.Conclusions.Young subjects with high normal BP seem to be at higher risk, and should undergo early and effective preventive measures.
RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN PATIENTS WITH ABDOMINAL OBESITY AND ARTERIAL HYPERTENSION
Authors: Bazhenova E. A. , Belyaeva O. D. , Berezina A. V. , Karonova T. L. , Kolodina D. A. , Brovin D. L. , Naneishvili T. Z. , Korelskaya N. A. , Ivanova T. G. , Baranova E. I. , Berkovich O. A. , Shlyakhto E. V. 
Published: December 2018

Objective. The activity of renin-angiotensin-aldosterone system (RAAS) is increased in patients with ab-dominal obesity (AO). However, till present time it is unclear whether RAAS activation or hypertension (HTN) found in 50 % patients is the primary disorder.Design and methods. We have studied plasma renin activity (PRA), plasma aldosterone concentration (PAC), their ratio PAC/PRA in patients with AO and related HTN and in subjects without AO.Results. PRA was higher in patients with AO versus people without obesity (2,5 ± 0,2 and 1,7 ± 0,7 ng/ml/hr, p = 0,013), there was a tendency to the reduction of the ratio PAC/PRA in obese patients (14,6 ± 0,9 and 19,7 ± 3,3, p = 0,08). In the subgroup of patients with AO and HTN the PRA was higher, and the ratio PAC/PRA was lower than in obese patients without HTN (PRA: 3,3 ± 0,4 and 1,7±0,2 ng/ml/hr, p = 0,005; PAC/PRA: 11,4 ± 1,1 and 17,4 ± 1,4, p < 0,0001). PRA and systolic blood pressure positively correlated. In patients with morbid obesity (3 degree according to the WHO classiication) obesity may play a signiicant role in the increase of RAAS activity, especially in the absence of concomitant HTN. The ratio PAC/PRA in over weight patients with AO was higher than in patients with AO and body mass index ? 30,0 kg/m (17,2 ± 1,7 and 12,5 ± 1,0 kg/m, p = 0,04). PRA was higher only in patients with AO and co-existing hypertension (3,4 ± 0,7 and 1,1 ± 0,2 ng/ml/hr, p = 0,04).Conclusions. RAAS activity is increased in patients with AO, also due to the co-existing HTN. However, in the absence of elevated blood pressure obesity per se may play a signiicant role in RAAS hyperactivity.
HYPERTENSION OFFICE: OPPORTUNITIES AND PROSPECTS FOR PRIMARY HEALTH CARE
Authors: Paskar N. A. 
Published: December 2018

Objective. To analyze the work of the Hypertension office to explore the risk factors of cardiovascular disease and prevention opportunities.Design and methods. The study included 2049 subjects (1549 women and 500 men) surveyed in 10 Hypertension offices. The special software «Cardiometer-MТ» JSC «MICARD-LANA» (Russia) was used for the automated integral estimation of the functional state of the cardiovascular system.Results. The fatal cardiovascular risk by the SCORE scale was estimated: very high risk was observed in 33,7 % cases, high risk — in 31,1 %, moderate risk — in 12,4 %, low risk — in 19,7 % cases. Conclusions. The methods applied in this work contribute to the development of the database and to the primary prevention in people with cardiovascular risk factors.
Infecciones oportunistas post inicio de tratamiento antirretroviral en pacientes con VIH/SIDA en un hospital público de Perú
Authors: Montalvo Raúl Héctor , Mejía Jhonatan R , Ramírez Percy , Rojas Eder , Serpa Henry , Tiza Víctor 
Published: December 2018

Introducción: El Tratamiento antirretroviral (TAR) suprime la replicación viral del VIH aun así ocurre las infecciones oportunistas (IOs) post inicio del TAR. Objetivo: Identificar y comparar las infecciones oportunistas (IOs) en pacientes con infección por VIH/SIDA que inician TAR en un hospital público de Perú. Materiales y métodos: Se realizó un estudio observacional de cohorte prospectivo de 8 años de seguimiento a los pacientes con infección por VIH/SIDA que iniciaron TAR. Resultados: De 427 pacientes estudiados, 111 (26%) presentaron por lo menos una infección oportunista. Los pacientes que presentaron IOs tuvieron una media de CD4: 107,5 células /ml, mientras que este conteo fue más alto en los pacientes sin coinfección (p<0,01), la carga viral no está relacionada con la presencia de IOs (p = 0,48). Las infecciones más frecuentes fueron: tuberculosis (43,2%), diarrea crónica (29,7%), candidiasis (10,8%), toxoplasmosis, citomegalovirus (4,5%) y Pneumocistosis (3,6%). Conclusiones: A pesar de los avances en el manejo de la infección por VIH/SIDA, las IOs continúan siendo la principal causa de hospitalización y la tuberculosis es el factor más importante asociado a mortalidad.
Proceso enfermero a paciente pediátrico con ependimoma grado II: estudio de caso
Authors: González-Castillo María Guadalupe , Díaz-Avila Alma Lucero 
Published: December 2018

Introducción. El Proceso Enfermero representa el eje metodológico de enfermería para brindar cuidados individualizados, de allí que el siguiente destaque los cuidados a una paciente con ependimoma grado II; tumor que se originan a partir de células ependimarias que revisten las paredes de los ventrículos cerebrales y/o el canal central de la medula espinal. Objetivo. Diseñar un plan de cuidados de enfermería personalizado para la atención a la paciente pediátrica con Ependimoma clásico Grado II en base a la teoría General de Dorothea Orem. Descripción. Paciente de 14 años de edad, quien inicia padecimiento presentando cefalea opresiva de irradiación a cervicales con exacerbación al colocarse en decúbito dorsal, náuseas, vomito en proyectil, disminución de la fuerza muscular en hemicuerpo izquierdo y desviación de la comisura labial hacia la derecha, es diagnosticada con epéndimoma clásico de grado II y se inicia tratamiento secuencial con radioterapia y agentes citotóxicos, compuesto tipo tiol, inhibidores de los receptores H2 y antieméticos. Discusión. De los 15 diagnósticos enfermeros incluidos para la atención de la paciente se contribuyó a mejorar su calidad de vida y se hizo evidente que el papel que la enfermera desempeña en el cuidado del paciente oncológico adolescente es imprescindible considerando que la puntuación diana total posterior a la intervención incremento de manera considerable.
HUMAN RIGHT DIMENSION IN HEALTH SERVICE (Functional Relation among Doctor, Patient, and Hospital)
Authors: Suharto Bekti 
Published: December 2018

This research aimed at analyzing exposure of global capitalism which undermines sense humanity in health services in Indonesia, explaining health care policy, and designing model of functional relationship among doctors, patients, and hospitals, based on human rights. This qualitative research used socio-legal approach. Primary and secondary data were collected by using observation, interviews, and documentation study. Data were analyzed through interactive data analysis process. It found sense of humanity in health services was undermined due to health market laws. Health care policy was a form of health development plan based on law principles which fulfill human rights of health, in terms of its functional relationship among doctors, patients, and hospitals, carried out by implementation of Pancasila, Leadership Trilogy of Ki Hajar Dewantara, Tri Dharma teachings of Mangkunegara I, KH. Ahmad Dahlan teachings, and teachings of Shiddiq, amanah, tabligh, fathonah, either by hospitals, doctors, and patients, on administrative, medical, or social services.Keywords: Capitalism, Health Legal Policy, Human Rights Dimension, Principles.
The Experimental and Theoretical Studies on Corrosion Phenomena of a Welded Stainless-Steel Pipe Under Salt Vapor Conditions
Authors: Yingsamphancharoen Trinet , Siripaiboon Chootrakul , Rodchanarowan Aphichart 
Published: December 2018

This work studied the corrosion of welded pipes and how welding destroyed surface film of pipes. Surface reaction of a welded pipe is key to understanding phenomena and important factors during the corrosion. This paper presents experiment and CFD modeling approaches of a welded pipe corrosion under salt vapor condition. The pipes were welded at currents of 60 A,70 A and 80 A to observe the effect of welding current on corrosion. A welded pipe is a stainless-steel ASTM A312 grade 304L and period of experiment about 0-600 hours that they are tested in vertical and horizontal alignments. In CFD software, there is not direct model of corrosion but it can use surface reaction and create add-on species and chemical reaction technique for imitating the corrosion mechanism. The modeling approaches of corrosion have presented in 3-dimensional transient times in CFD simulation. Surface reactions were performed by Species Model which involve site species. Site species in Species Model took place at gas-solid interfaces and in this case are salt vapor and surface pipe. Chemical reaction rate on the surface controls lost weight of a welded pipe and the model can be validated with experiment. In conclusion, in period 0-600 hours error between CFD modeling and experiment have error trend decreased. The error at 600 hours is 6% both of vertical pipe and horizontal pipe test. The modeling approaches closely with the performed experiment and can be accepted. Moreover,
the model is able to predict corrosion of a welded pipe of different sizes and their lost weight after 600 hours without experiment. Also the model can predict lifetime of pipe.
Estimasi Komponen Variansi pada Rancangan Faktorial Acak Lengkap Menggunakan Metode Generalized Least Squares
Authors: Angriany A. Muthiah Nur , Tinungki Georgina Maria , Raupong Raupong 
Published: December 2018

AbstractsExperiment design is a test or a row of test by using both statistical description and inference statistical. The aim of this test is to change an input to become an output as a respond of the experiment. In the experiment design, variance of factor A, B , AB error of variance are called as variant component. The aim of this study is to estimate variance component on complete random factorial design for fixed model and mixed model by using Generalized Least Squares (GLS)method, where GLS method as a development of Ordinary Least Square method. It used to be applied on data of complete random factorial design, namely like the influence to density pelleting food which is caused by increasing adhesive material and longtime in storage. The results show that there is no influence of increasing adhesive material to the density of pelleting food. In addition, there exist of diversity of longtime of storage and there exists a diversity interaction between adding adhesive material and long of time of storage to the density of pelleting food Keywords: Generalized Least Squares, variance component, complete random factorial design AbstrakPerancangan percobaan adalah suatu uji atau sederet uji baik itu menggunakan statistika deskripsi maupun statistika inferensi, yang bertujuan untuk mengubah peubah input menjadi suatu output yang merupakan respon dari percobaan tersebut. Dalam perancangan percobaan, variansi dari faktor A, variansi dari faktor B, variansi interaksi faktor AB, dan variansi galat disebut dengan komponen varian. Penelitian ini bertujuan untuk mengestimasi komponen variansi pada rancangan faktorial acak lengkap model tetap dan model campuran menggunakan metode Generalized Least Squares (GLS), dimana metode GLS adalah pengembangan dari metode Ordinary Least Square yang biasa digunakan untuk mengatasi asumsi homogenitas yang biasa dilanggar dalam perancangan percobaan. Metode tersebut diterapkan pada data rancangan faktorial acak lengkap yaitu pengaruh berat jenis pakan pellet dengan kombinasi perlakuan penambahan bahan perekat dan lama penyimpanan. Hasil menunjukkan bahwa tidak terdapat pengaruh penambahan bahan perekat terhadap berat jenis pakan pellet. Selain itu, terdapat keragaman faktor lama penyimpan dan terdapat keragaman interaksi antara faktor penambahan perekat dan lama penyimpanan terhadap berat jenis pakan pellet. Kata kunci: Generalized Least Squares, komponen variansi, rancangan faktorial acak lengkap
Some Properties of Fundamental Linear Canonical Zak Transform
Authors: Asriadi Asriadi , Nurwahyu Budi , Bahri Mawardi 
Published: December 2018

AbstractIn this paper, we introduce some fundamentally properties of Zak linear canonical transform (LCZT) such as linearity and translation properties. LCZT is developing of Zak transform ( ZT) and linear canonical transform (LCT). Keywords: linear canonical Zak transform; Zak transform; linear canonical transform; linearity property; translation property. AbstrakDalam jurnal ini akan diungkapkan beberapa sifat fundamental dari transformasi Zak linear kanonik (LCZT), yaitu sifat linear dan sifat translasi. LCZT merupakan hasil pengembangan dari dua buah transformasi yaitu transformasi Zak (ZT) dan transformasi linear kanonik (LCT). Kata kunci:Transformasi Zak linear kanonik; transformasi Zak; transformasi linear kanonik; sifat linear; sifattranslasi.