bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Paparan Medan Magnet 0,2 mT pada Ion Logam Fe dan Zn dalam media pertumbuhan terhadap produksi Protease Bacillus sp
Authors: Sumardi Sumardi , Agustrina Rochmah , Irawan Bambang , Selfiana Indah 
Published: December 2018

ABSTRAKTujuan penelitian ini adalah mengetahui pengaruh paparan medan magnet 0.2 mT pada ion logam Fe dan Zn dalam media pertumbuhan terhadap produksi protease Bacillus sp. Ion logam yang digunakan yaitu Fe dan Zn dalam bentuk garam FeCl3 dan ZnCl2. Hasil penelitian menunjukkan bahwa ion logam Fe (0.01% b/v) yang terpapar medan magnet mempunyai nilai Indeks Proteolitik 3,36 dengan lama inkubasi 10 jam, dan indeks proteolitik 2,74 dengan lama inkubasi 18 jam. Sedang ion logam Fe (0.01% b/v) yang tidak terpapar medan magnet mempunyai nilai Indeks Proteolitik 1,79 dengan lama inkubasi 10 jam, dan indeks proteolitik 2,12 dengan lama inkubasi 18 jam. Sedangkan pada ion logam Zn (0.005% b/v) yang terpapar medan magnet dan tidak terpapar medan magnet menyebabkan aktivitas Bacillus mati. Larutan ion logam Fe 0,01% dalam media cair menghasilkan produksi protease lebih baik (0,06 U/ml) dibandingkan dengan produksi protease tanpa dipemapar medan magnet (0,00 U/ml).Kata kunci: Bacillus sp., paparan medan magnet, indeks proteolitik.ABSTRACTThe purpose of this study was to determine the effect of metal ions Fe and Zn were exposed to a magnetic field of 0.2 mT to the production of proteases in Bacillus sp. The metal ions used are Fe and Zn in the form of FeCl3 and ZnCl2 salts. The results showed that the culture medium containing metal ions Fe (a 0.01% w/v) were exposed by the magnetic field has a value of proteolytic index of 3.36 with 10 hour long incubation, and proteolysis index of 2.74 with 18 hour incubation time. Culture medium containing metal ions Fe (a 0.01% w/v) which are not being exposed to the magnetic field has a value of proteolytic index of 1.79 with 10-hour long incubation, and proteolysis index of 2.12 with 18 hour incubation time. While the culture medium containing metal ions Zn (0.005% w/v) either exposed or not exposed to the magnetic field causes the activity of Bacillus sp die. The solution of 0.01% Fe metal ion in liquid medium resulted in better protease production (0.06 U/ml) than production of proteases without exposure to magnetic fields (0.00 U/ml)Keywords: Bacillus sp., magnetic field, proteolytic index, and proteolysis indexSitasi: Sumardi, Agustrina R., Irawan B., dan I. Selfiana. (2018). Pengaruh Paparan Medan Magnet 0,2 mT pada Ion Logam Fe dan Zn dalam media pertumbuhan terhadap produksi Protease Bacillus sp. Jurnal Ilmu Lingkungan, 16(2), 173-177,doi:10.14710/jil.16.2.173-177
Risk factors of peripheral neuropathy in patients with type 2 diabetes in Isfahan: Results of a cohort study in Iran
Authors: Mohammadian-Hafshejani Abdollah , Majdzadeh Reza , Mansournia Nasrin , Mansournia Mohammad Ali 
Published: December 2018

Introduction: Peripheral neuropathy (PN) is among the most prevalent complications of diabetes that can lead to impairment of mobility of diabetic patients. The purpose of the current study was to predict relative factors influencing the occurrence of peripheral neuropathy (PN) in patients with type 2 diabetes.
Methods: This was a cohort study on diabetic patients in the Isfahan Province of Iran. The studied population consisted of patients with type 2 diabetes, of ages 18 or older, who were diagnosed as new cases of diabetes from 2007 to 2014, and whose follow-up was completed by the end of 2016. In this study, with regards to the presence of time-varying co-variates, timedependent Cox regression model was employed in order to estimate the Hazard Ratio (HR) of PN in the diabetic patients.
Results: Overall, 1874 patients with diabetes participated in the study, of which 839 (44.77%) were men and 1035 (55.23%) were women. During the study period, PN occurred in 17.98% of the patients; the ratio was 17% in women and 19.18% in men. In comparison to the reference group, the adjusted HR of PN in males was equal to 3.66 (95% CI: 1.15-11.67), in housewives was equal to 4.09 (95% CI: 1.02-16.38), and divorced or wife died patients was equal to 3.02 (95% CI: 1.61-5.65). In addition, for each 6 month follow-up of the patients, the adjusted HR of PN increased to 1.19 (95% CI: 1.17-1.22).
Conclusions: The adjusted HR of PN in men, in housewives, and elderly people, divorced or wife died patients, with elementary education level were greater than the reference group. Thus, training, screening and diagnostic programs should be carried out with greater sensitivity in patients who are at greater risk for PN.
Review article
Authors: Laing Dave 
Published: December 2018

This review article discusses several books dealing with aspects of live music, notably festivals and arena concerts. It points out that, for the most part, two edited collections on festivals are purely celebratory and focus on audience experience rather than the character of performances. In contrast, two book-length studies of individual folk and rock festivals provide a more comprehensive account, including the extent of local opposition to the staging of the 1970 Isle of Wight Festival. Finally, the article finds much to commend in an edited volume on the arena concert.

George MacKay, ed. The Pop Festival: History, Music, Media, Culture. London: Bloomsbury, 2015. xx + 234 pp. ISBN 978-1-62356-959-4 (pbk).

Andy Bennett, Jodie Taylor and Ian Woodward (eds). The Festivalisation of Culture. Farnham, Surrey: Ashgate, 2014. xiii + 279 pp. ISBN 978-1-4094-3198-5 (hbk).

Ray Foulk with Caroline Foulk. The Last Great Event: When the World Came to the Isle of Wight. Surbiton, Surrey: Medina Publishing, 2015. xx + 364 pp. ISBN 978-1-909339-58-3 (pbk).

Derek Schofield. Towersey Festival: 50 Years in the Making. Matlock: Mrs Casey Music, 2014. iv + 172 pp. ISBN 978-0-9547502-1-3 (pbk).

Robert Edgar, Kirsty Fairclough-Isaacs, Benjamin Halligan and Nicola Spelman (eds). The Arena Concert: Music, Media and Mass Entertainment. London: Bloomsbury, 2015. xv + 331 pp. ISBN 978-1-6289-2555-5 (pbk).
Jonathan Pieslak. 2015. 'Radicalism and Music: An Introduction to the Music Cultures of al-Qa’ida, Racist Skinheads, Christian-Affiliated Radicals, and Eco-Animal Rights Militants'
Authors: Dietsche Sarah 
Published: December 2018

Jonathan Pieslak. 2015. Radicalism and Music: An Introduction to the Music Cultures of al-Qa’ida, Racist Skinheads, Christian-Affiliated Radicals, and Eco-Animal Rights Militants. Middletown, CT: Wesleyan University Press. ISBN 978-0-8195-7584-5 (pbk). 344 pp.
Johannes Brusila, Bruce Johnson and John Richardson, eds. 2016. <i>Memory, Space, Sound</i>
Authors: Ahlers Michael 
Published: December 2018

Johannes Brusila, Bruce Johnson and John Richardson, eds. 2016. Memory, Space, Sound. Bristol: Intellect. ISBN 978-1-78320-602-5 (hbk), 978-1-78320-603-2 (ePDF), 978-1-78320-604-9 (ePub). 231 pp.
Analysis of Some Indicators Characterizing the Quality of Medical Care for Children with Cancer in the South Federal District of the Russian Federation: An Ecological Study
Authors: Rykov M. Yu. 
Published: December 2018

Background. Improving the quality of medical care is based on a coordinated policy at the federal, regional and municipal levels in the field of health. The implementation of this goal is based on a regular assessment of the current state of the healthcare system in the Russian Federation.Objective. Our aim was to analyse of the main indicators characterizing medical care for children with cancer in the South Federal District.Methods. The operative reports for 2017 of the executive authorities in the sphere of health protection of 8 subjects of the Russian Federation that are part of the South Federal District of the Russian Federation have been analyzed.Results. The number of children were 3 216 797 people (aged 0–17 years), the number of children’s oncological beds is 272 (0.8 per 10 thousand children aged 0–17 years), the average number of days of berth employment in the year is 289.9 bed days. In 4 (50%) subjects of the department of pediatric oncology are absent, in 1 (12.5%) — there are no children’s oncological beds. The number of doctors providing medical care to children with cancer is 50, of them 42 (84%, 0.1 per 10 thousand children aged 0–17 years) have a certificate of a pediatric oncologist. In 2 (25%) subjects, there are no pediatric oncologists. Incidence of malignant tumors was 13.9 (per 100,000 children aged 0–17 years), prevalence was 86.5 (per 100,000 children aged 0–17 years), mortality was 2.5 (per 100,000 children aged 0–17 years), a one-year mortality rate of 4.7%. 8% of patients were actively detected. 104 (23.2%) of primary patients were sent to medical organizations of federal subordination, 4 (0.9%) of primary patients left the territory of the Russian Federation.Conclusion. The analysis revealed a number of defects: incorrect information contained in the reports, low incidence (detectability) of patients, including during planned preventive examinations, staff shortages and non-rational use of bed facilities.
Atypical Teratoid Rhabdoid Tumor of Spinal Cord: A Clinical Case
Authors: Olkhova Liudmila V. , Zheludkova Olga G. , Ryzhova Marina V. , Kushel Yury V. , Kryanev Alexander M. , Ozerova Valentina I. 
Published: December 2018

Background. Atypical teratoid rhabdoid tumor (AT/RT) of the central nervous system (CNS) is an aggressive malignant tumor, mostly affecting children younger than 3 years old. AT/RT is characterized by the deletion and/or mutation of gene SMARCB1/INI1, located in the long arm 22q11, leading to a loss of the nuclear expression of protein INI1, which may be detected by immunohistochemical assay with the anti-INI1 antibody. These tumors are mostly located in the brain, and their incidence in the spinal cord is very rare, with just a few publications on their clinical observations.Description of a Clinical Case. A clinical example of AT/RT in a two-year patient with the tumor located in the thoracic and lumbar spinal cord is described. The patient underwent surgical treatment consisting in the tumor resection and also chemoradiotherapy. Evaluation showed complete response. By the moment this paper was written, the duration of event-free survival of this patient was 27 months.Conclusion. This paper reviews the earlier published cases of spinal cord AT/RT, in which the most common location of the tumor was the cervical portion of the spinal cord. The maximum overall survival was 18 months, and the average overall survival was 9 months. In our clinical example, we demonstrate a long-term complete response to the multimodal treatment for AT/RT.
Küresel Ölçekte Yazılım Kalitesi ve Standartları: Sektörel ve Bilimsel Perspektiften Literatürdeki Eğilimler
Authors: Damar Muhammet , Özdağoğlu Güzin , Özdağoğlu Aşkın 
Published: December 2018

Dijital dönüşümün gereği, iş ve günlük yaşamın pek çok bileşeninde
yazılımlardan faydalanılmaktadır. Bu alanda ürün çeşitliliği ve rekabet arttıkça
sektöre yön veren kalite ve standart çalışmaları da gündeme gelmektedir. Bu bağlamda
çalışmanın amacı, yazılım kalitesi ve standartlarının mevcut durumunu gerek
sektörel gerekse bilimsel yayınlar açısından ortaya koymaktır. Çalışma
kapsamında, bu alanda yapılan çalışmalar özetlenmekte, ardından, bu konuda Web
of Science temel veri tabanında taranan dergilerde yayınlanmış araştırma
makalelerinin bilimetrik analizi ile elde edilen bulgular sunulmaktadır. Bulgular,
bu alanda çalışan araştırmacılara, alandaki en aktif üniversite, yazar, ülke,
kurum bilgileri ile bu alanda yayın yapan yazarların çoğunlukla tercih
ettikleri alan dergileri, yıllar içinde anahtar kelimelerin eğilimlerini
vurgulamaktadır. Ayrıca,
ülkeler boyutunda makale sayıları ve
nitelikleri de ele alınarak Türkiye’nin içinde bulunduğu durum tartışılmaktadır.
Characteristics of Brown Seaweeds Sargassum policystum and Padina minor from Pohuwato Water, Gorontalo
Authors: Manteu Shindy Hamidah , Nurjanah Nurjanah , Nurhayati Tati 
Published: December 2018

Brown seaweed is one of the abundant resources that grows on the reefs of Pohuwato, Gorontalo Province. This research was aimed to determine the characteristics of <em>S. polycystum</em> and <em>P. minor</em> as sources of salt for hypertensive patients. The research consisted of proximate analysis, minerals, heavy metals, extraction, phytochemicals, phenols analysis, and antioxidant activity. <em>S. polycystum, P. minor</em> had water content of 17.69-22.31%, ash 24.51-30.53%, fat 0.50-0.52%, protein 3.65-4.78%, carbohydrates 53.66-41.88 and crude fiber 3.81-6.52%. The seaweeds also contained Mg 8.89-22.41 mg/g, Fe 0.50-1.00 mg/g, K 26.90-32.71%, Na 22.23-22.69 mg/g, Ca 18.06-32.91 mg/g and ratio Na:K 0.69-0.83 mg/g. Heavy metals were detected in low levels with the content&lt;0.002-&lt;0.004 ppm. Ethanol extract of S. polycystum contained flavonoid, saponin, streoid, alkaloid. Meanwhile ethanol extract of <em>P. minor</em> contained flavonoid, saponin, triterpenoid, stereoid, phenol, dan alkaloid. Total phenol level of<em> S. polycystum</em> was 173.6 mg GAE/g and <em>P. minor</em> was 568.7 mg GAE/g. The antioxidant IC50 of <em>S. Polycystum</em> was 77.58 mg/L while <em>P. minor</em> was 66.38 mg/L.
Bayesian Modelling of the effects of nitrogen doses on the morphological characteristics of braquiaria grass
Authors: Marra da Silva Ribeiro Luiz Henrique , De Souza Costa Matheus , Alberto Beijo Luiz , Lázaro Aguirre Alberto Frank , Gomes de Araújo Tatiane , Dos Santos Alves Josiane 
Published: December 2018

The Bayesian approach in regression models has shown good results in parameter estimations,
where it can increase accuracy and precision. The objective of the current study was to analyze the application
of Bayesian statistics to the modeling yield for leaf dry matter (LM) and stem (SM), in kg ha-1, leaf ratio (LR),
crude protein content for leaves (CPL) and stem (CPS) (%) of Brachiaria grass as a function of varying N doses
(0; 100; 200 and 300 kg ha-1 yr-1). Simple and two degree polynomial linear regression models were analyzed.
Information for a priori distributions was obtained from the literature. A posteriori distribution was generated
using a Monte Carlo method via Markov chains. Parameters significance was assyed with HPD (Highest
Posteriori Density) with a 95% interval. Model selections was performed using DIC (Deviance Information
Criterion); and adjustment quality estimated with means and 95% HPD for Bayesian R2 distribution ranges.
The models selected for the variables LM, SM and CPS were linear, while for LR and CPL, they were second
level polynomial. The lowest doses that maximize response variables were: LM: 274 ha-1yr-1, SM: 280 ha-1yr-1,
LR: 113 ha-1yr-1, CPL: 265 ha-1yr-1, CPS: 289 ha-1yr-1. The Bayesian approach allowed the inclusion of literatureverified
a priori information, and the identification of evidence optimization range intervals.
Mu’tezile ve Şîa Arasında Fikri Bağlantı Meselesi İlahi Adalet İlkesi Bağlamında Kâdî Abdülcebbâr ve Ebû Ca’fer et-Tûsî Arasında Bir Karşılaştırma
Authors: KORKMAZGÖZ Rıza 
Published: December 2018

Özet

Şii-İmamiyye’nin usûlde
Mu’tezilenin etkisinde kaldığı iddiaları, hicri dördüncü asırdan itibaren dile
getirilmektedir. Buna karşılık usûlî düşüncenin ilk mümessili sayılan Şeyh
Müfîd’den itibaren mezhep içinden yükselen sesler bu iddiaları şiddetle reddetmişlerdir.
Biz bu çalışmada Mu’tezile kelamına sistematik hüviyet kazandıran ve yazdığı
eserlerle Mu’tezile kelamının bugüne ulaşmasında büyük pay sahibi olan Kâdî
Abdülcebbâr ile İmamiyye’nin kelam düşüncesinin istikrar bulmasında ve Şeyh
Müfîd’le başlatılan usûlî yaklaşımın benimsenip yaygınlaşmasında büyük bir yeri
olan Ebû Ca’fer et-Tûsî arasında adalet ilkesi üzerinden bir karşılaştırma
yaparak, söz konusu iddiaların ne kadar sübut bulduğunu tespit etmeye çalıştık.
Kısmi farklı izahları bir kenara bırakırsak, adalet ilkesinin ispat ve
yorumlanmasında iki kelamcı arasında kayda değer bir farklılığın olmadığı
görülmektedir. Abstract The claim that the Shi’i
Imamite thought is heavily influenced by
the Mu’tazilite outlook has been alleged since the fouth century of hijra.
However, beginning with Shaikh Mufid, the first representative of the Usuli
branch of Shi’a, the Shi’is vehemently denied this allegation. In this article,
this issue is dealt with by making a comparison between the idea of Qadi Abd
al-Jabbar, the prominent Mu’tazilite scholar who made a major contribution to
the consolidation of the schools’ theaching and that of al-Tusi, who also made
a contrubitued to the integration of the Shi’ite kalam and the spreading of the usuli approach
initiated by Shaikh Mufid. Leaving aside the differences in deatil, it seems
that there is no noteworthy difference between their approcah to the issue of
justice.

Key Words: Qâdî Abd al-Jabbâr, Abû Ja’far al-Tûsî,
Husn-Qubh, Divine Justice, Free Will
Alevî Nitelemeli Ocak / Gruplara Ait Tekke, Zâviye ve Dergâhlardaki Cami ve Mescidler
Authors: ÜÇER Cenksu 
Published: December 2018

Bu çalışmada günümüzde
daha çok Alevî nitelemesi kullanılan gruplara ait tekke, zâviye ve dergâhlarda
bulunan cami ve mescid varlığı ele alınmaktadır. Bilindiği gibi söz konusu bu
gruplar geçmişte her biri Bektâşî, Erdebil Sûfiyân Süreği Mensubu (Kızılbaş),
Tahtacı, Dede Garkınlı, Hubyarlı, Keçeci Babalı gibi mensup olduğu ocak ismiyle
isimlendirilmiştir.

Söz konusu bu ocakların her biri, bütün telakkîlerini
tasavvuf ve tarikat hayatı kalıplarında anlamlandırmıştır. Alevî nitelemeli
ocak ve gruplar geçmişte içlerinde “tevhid” kısmının da bulunduğu âdâb ve
erkânı, diğer tasavvufî ekollerde ya da tarikatlarda olduğu gibi, tekke, zâviye
ve dergâhlarda; tekke, zâviye ya da dergâhın bulunmadığı yerleşim yerlerinde
ise gerekli büyüklükte evi olan bir dede ya da talibin evinde toplanıp
yürütmüşlerdir.

Tarihi
sürece ve pratik uygulamaya bakıldığında, tasavvuf ekolleri ve tarikatlara ait tekke,
zâviye ve dergâhların yanında namaz kılmak için bir cami ve mescit bulunduğu
bilinmektedir. Bu pratik durumun Hacı Bektâş Velî, Seyyid Battal Gazi,
Şücâaddin Velî, Abdal Musa, Keçeci Baba gibi Alevî nitelemeli ocak ve grupların
geleneksel âdâb ve erkân merkezleri tekke, zâviye ve dergâhlarda da söz konusu
olduğu görülmektedir.

Bu
konuda yapılacak çalışma ve değerlendirmelerin bu gerçekliği dikkate alması
yerinde olacaktır.
Rural-Urban	Differences	in	Stroke	Types,	Risk	Factors,	Severity	and Prognosis in Babol, Northern Iran
Authors: Saadat Payam , Ahmadi Ahangar Alijan , Khafri Soraya , Kalantar Mandana , Dariaie Azin , Alijanpour Shayan , Mortazavinejhad Roghayyeh , Faraji Sekineh , Frajzadeh Fatemeh 
Published: December 2018

Introduction: Stroke recognized as the third most common cause of death. Stroke survivors often suffer a large amount of physical and mental disability. Due to assess difference between stroke types, progression and distribution of risk factors according to residential status, to get the correct information for prevention planning and management, this study was conducted.
Methods: This descriptive cross-sectional study on stroke patient from 2016 to 2017 that admitted to Ayatollah Rohani Hospital of Babol was conducted. Type of stroke, their severity, risk factors, and urban or rural area of residence of patients were recorded in the checklist. The chi-square test was used to compare frequencies of gender, and stroke risk assessment between the urban and rural residents. Binary logistic regression modeling was used to estimate the association of risk factors with living in urban and rural areas. The results were expressed as multivariable-adjusted odds ratios (ORs) and 95 % confidence intervals (95 % CIs). A two-sided p < 0.05 was considered statistically significant. All data analyses were performed, using SPSS statistical analysis software.
Results: Of 241 stroke patients, 133 patients (55 %) were female and 213 patients (88.4 %) were ischemic. Also, 140 cases were (58 %) rural. Embolic strokes more in urban population and thrombotic strokes were more in rural populations. Hyperlipidemia was more in urban than rural p = 0.01. Severity of stroke in admission time (p = 0.03) and at discharge (p = 0.005) was more in rural than urban. The mortality was higher in rural 12 (8.6) vs. 2 (2) urban resident,( p = 0.03).
Conclusion: Rural patients had more severity, thrombotic type and mortality than urban. Suitable policy regard to residential parameter is suggested.
Socio-Demographic Determinants of Quality of Life among Older People, a Population-Based Study
Authors: Momenabadi Victoria , Hossein Kaveh Mohammad , Nazari Mahin , Ghahremani Leila 
Published: December 2018

Introduction: Social participation is considered one dimension and also determinant of quality of life. The level of social participation of the elderly is influenced by various components such as socio-economic and demographic factors. The present study aimed to assess the relationship between social participation, quality of life, and some socio- economic factors in community dwelling elderly in Kerman, Iran.
Methods: This cross-sectional study was conducted on 250 communities dwelling old people in Kerman in 2017 selected through random sampling. The data were collected using researcher-made Social Participation questionnaire and WHOQOL-BREF questionnaires. The data were analyzed using Pearson’s correlation coefficient, t-test, one-way ANOVA, and linear regression analysis.
Results: The results revealed the participants’ mean score of social participation was above fifty. Social participation was significantly associated with age (p < 0.001), marital status (p = 0.004), education level (p < 0.001), and occupation (p = 0.021). A significant direct correlation was also observed between social participation and quality of life (p < 0.001), and social participation determined 21 % of variance of life quality score (p < 0.001).
Conclusion: With the increase in social participation of the elderly, their quality of life improves. Establishing nongovernmental organizations, charities, and associations for retirement and aging can increase the level of social participation of the elderly.
Associated Factors of Chronic Kidney Disease among Hyponatraemic Elderly Patients Attending a Primary Care Clinic
Authors: Li Tay Chai 
Published: December 2018

Introduction: Chronic kidney disease (CKD) emerges to be an important geriatric health issue. It may progress to end stage renal failure and affect the quality of life. However, little is known about the associated factors of CKD. So this study aimed to determine the associated factors of CKD among hyponatraemic elderly.
Methods: This is a retrospective study of hyponatraemic patients aged ≥ 60 years attending outpatient clinic in 2014. Blood test results of glucose, potassium, creatinine, medical history, blood pressure, medication and demographic data were captured from patient records. Each patient’s estimated glomerular filtration rate (eGFR) was calculated using the CKD-EPI Creatinine Equation. CKD is defined as eGFR of < 60 ml/min/1.73m2. SPSS 21 was used to do the analysis.
Results: Totally 257 patients with mean age of 72.9 ± 7.3 years were enrolled in this study. Of them 73 (28.4 %) elderly had CKD. The mean eGFR was 72.62 ± 24.14 ml/min/1.73m2, mean BP was (135.75 ± 18/10) mmHg. Of the participants, 134 (52.1 %) were men, 151 (58.8 %) were diabetics, 247 (96.1 %) had hypertension. The independent associated factors of CKD were increasing age (OR 1.08; 95 % CI 1.03-1.13; p = 0.002), hyperglycaemia (OR 1.10; 95 % CI 1.02-1.18; p = 0.017) and the use of loop diuretics (OR 5.15; 95 % CI 1.52-17.38; p = 0.008).
Conclusion: Hyperglycaemia and loop diuretics usage are found to be significantly associated with CKD among elderly patients attending a primary care clinic. Hence every effort should be made to optimise glucose control and cautious in the usage of loop diuretics to retard the decline in renal function.