bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular genetic aspects of early diagnosis and personalized treatment of obliterating atherosclerosis of lower limb arteries
Authors: V. G. Mishalov  , V. A. Cherniak  , L. V. Natrus  , B. M. Koval  , V. M. Holinko  , S. O. Makhynia  
Published: January 2019

Obliterating atherosclerosis of lower limb arteries (OALLA) is a multifactorial disease, which results from the complex influence of genetic, epigenetic and environmental factors. Nowadays the role of about 50 single‑nucleotide genetic polymorphisms (SNPs) has been proven in the pathogenesis of OALLA. Conducting the genetic screening and determining the susceptibility to the development of OALLA will allow for the timely prevention of the disease by modifying the lifestyle and diet. Since the mere presence of a genetic mutation does not always lead to the synthesis of a defective protein, the treatment of the disease can begin even before the onset of clinical symptoms, but only after the detection of the earliest pathological biochemical markers of the disease, in this case — endothelial dysfunction. The use of modern methods of molecular biology, with consideration of the molecular genetic characteristics of the patient, will allow timely prevention, early diagnosis of the disease after detection of biochemical markers of endothelial dysfunction, individualization of the choice of conservative drugs, and therefore increase in their effectiveness and safety, delay of the start of surgical treatment and reduction of disability in patients with OALLA.
Long-term effects of fertilizer and manure application on soil quality and sustainability of jute-rice-wheat production system in Indo-Gangetic plain
Authors: Kundu D. K. , Mazumdar S. P. , Ghosh D. , Saha A. R. , Majumdar B. , Ghorai A. K. , Behera M. S. 
Published: January 2019

A long-term fertilizer experiment was initiated in 1971 in sandy loam soil (Eutrochrept) of Barrackpore, West Bengal to study the effects of applying organic and inorganic sources of nutrients on yield of jute-rice-wheat system and soil health. The unfertilized soil supported yields of 0.8 t ha-1 of jute fibre, 1.5 t ha-1 of rice grain and 0.7 t ha-1 of wheat grain (average yield of 42 years). Application of 150% recommended NPK through chemical fertilizers produced maximum yields of jute (2.1 t ha-1), rice (3.8 t ha-1) and wheat (2.8 t ha-1). The yields obtained with 150% NPK fertilizers were 5%, 2.7% and 12% higher than that with 100% NPK fertilizers +FYM. Combined application of 100% NPK fertilizers and FYM, however, increased soil organic carbon, available nitrogen, phosphorus and potassium from 5.60 to 8.90 g kg-1, 270 to 316 kg ha-1, 40.7 to 120 kg ha-1 and 139 to 236 kg ha-1 respectively. Maximum DTPA-extractable micronutrients in soil were also observed with 100%NPK fertilizers+FYM. Applying FYM together with NPK fertilizers increased microbial biomass from 221 to 435 mg kg-1 and microbial quotient from 3.95 to 4.89 with concomitant increase in dehydrogenase, phosphatase and fluorescein-diacetate-hydrolyzing activities in the soil. The acid phosphatase activity (139 to 275 ?g PNPg-1 h-1) was much lower than alkaline phosphatase activity (479 to 616 ?g PNPg-1 h-1). The enzymes assayed showed significant correlation with microbial-C and organic C. Beneficial effects of integrated nutrient management (NPK+FYM) on soil health were reflected on the yields of all the crops.
Knowledge, Attitude and Practice of Using ORS and Household Management of Childhood Diarrhoea
Authors: Acharya Naresh Chandra , Dash Dillip Kumar , Mohanty Mamata Devi , Agarwal Priyanka , Dey Pratik 
Published: January 2019

Introduction: Diarrhoea is defined as the passage of three or more loose stools per day. Diarrhoea is one of the leading causes of childhood mortality in India. The objectives of the study were to assess household Knowledge, Attitude and Practice for prevention of Diarrhoea in children through preformed questionnaires.
Material and Methods: Four hundred and sixty eight under five children were selected for study by Cluster sampling method. Background information, details of acute diarrhoea and treatment modalities were obtained from mother of the under five children. This was a hospital based study conducted at a tertiary care hospital, from 1st May 2017 to 30th December 2017.
Results: About 70% of the moms were between the age assemble 25-32 years and the vast majority of them were housewives (72%). A greater part (>66%) of the moms were having essential/auxiliary education. Learning with respect to different parts of the diarrhoea and ORS surprisingly extremely unacceptable. In the present examination it is seen that learning in regards to ORS in looseness of the bowels is more in educated mother than uneducated. Three sitting of Educational mediations realized huge enhancement of the middle scores of learning, state of mind and practice expanded from 9, 6, 3 to 19, 14, 8, individually,
Conclusion: The household knowledge regarding method of use and preparation of ORS for management of diarrhoea was observed to be lacking in this investigation. More estimates should be taken to enhance this learning and make moms mindful about the planning and utilization of ORS.
Familial Chylomicronaemia: A Neonate with Milky White Blood
Authors: Chaudhary Nanda Kishwor , Chapagain Ram Hari , Sipai Sani , Chaudhary Suryakant , Paudel Krishan Prasad 
Published: January 2019

Familial Chylomicronaemia is a rare autosomal recessive disease of lipoprotein metabolism characterized by deficiency or absence of lipoprotein lipase (LPL) or its co-factor apoC-II which causes severe elevation of triglyceride and chylomicron resulting in lipaemic plasma, recurrent attacks of acute pancreatitis, eruptive xanthomas, hepato-splenomegaly and lipaemiaretinalis. We report a case of term female neonate with lipaemic plasma, lipemia retinalis, markedly elevated triglyceride level which is consistent with diagnosis of Familial Chylomicronaemia.
Keywords: Familial Chylomicronemia, lipemic plasma, triglyceride level, Lipemia retinalis
Assessment of Hand Hygiene Knowledge among Residents and Nursing staffs at Nobel Medical College Teaching Hospital, Biratnagar
Authors: Yadav Sunil Kumar , Giri Arun 
Published: January 2019

Introduction: Hand hygiene is a very simple and cost-effective procedure to prevent cross-transmission of microorganisms. The compliance of residents and nursing staffs with hand hygiene guidelines seems to be vital in preventing disease transmission among patients. The objective of the study was to assess the knowledge of residents and nursing staffs with regard to hand hygiene.
Material and Methods: This was an institution based descriptive cross-sectional study conducted among 55 respondents (29 nursing staffs and 26 resident doctors) of department of paediatrics, Nobel Medical College in Biratnagar, Nepal. Knowledge was assessed using WHO hand hygiene questionnaire for health care workers. Chi square test was used to compare the percentage of correct responses between resident doctors and nursing staffs. A p value of <0.05 was considered significant.
Results: Among 26 resident doctors and 29 nursing staffs who participated in the study, 30.7% of resident doctors and 55.1% of nursing staffs had received formal training in hand hygiene in the last three years. Only 9% of participants (5 out of 55) had good knowledge regarding hand hygiene.
Conclusions: The knowledge regarding hand hygiene is limited among the study population. The study recommends the need for emphasizing hand hygiene component in the preservice as well as in-service training programs of doctors and nurses.
Memantine and Acetylcholinesterase Inhibitor Use in Alzheimer’s Disease Clinical Trials: Potential for Confounding by Indication
Authors: Huisa Branko N. , Thomas Ronald G. , Jin Shelia , Oltersdorf Tilman , Taylor Curtis , Feldman Howard H. 
Published: January 2019

Background: Acetylcholinesterase inhibitors (AChEIs) and memantine are commonly prescribed medications for Alzheimer’s disease (AD). Their concurrent use in AD randomized clinical trials (RCTs) is generally allowed but their effect in outcome measures is unsettled. Objective: To evaluate whether use of AChEIs and/or memantine across AD RCTs are associated with different rates of cognitive/functional decline. Methods: We pooled data from 5 RCTs of mild to moderate AD conducted by the Alzheimer’s Disease Cooperative Study (ADCS) between 2002-2013. 1,423 participants with MMSE of 14–26 and completion of 12–18 months follow-up visits were analyzed. Trials did not randomize with respect to AChEIs or memantine. We defined 4 groups: AChEI (27%), memantine (16%), AChEIs+memantine (46%), and non-users (11%). Outcome measures were change in ADAS-cog-11, ADCS-ADL, and MMSE from baseline to 18 months. Fisher’s exact test, Wilcoxon signed rank, and Spearman’s tests were used to identify confounding variables. Mixed model repeated measures were used for adjustments and pairwise tests for comparing change in scores. Results: Age, apolipoprotein E, and initial MMSE were identified as covariates. Memantine and/or AChEIs users had greater impairment at entry than non-users. There was a significant decline on the ADAS-cog-11 in the memantine (estimate –4.2 p < 0.0001) and AChEIs+memantine groups (estimate –3.5 p < 0.0001) than non-users, while there was significantly more decline in MMSE (estimate 2.5 p < 0.0001) and ADCS-ADL in the AChEIs+memantine group (estimate 4.3 p < 0.0001) Conclusion: Memantine monotherapy or combined with AChEIs are associated with more rapid cognitive and functional decline than non-users. We postulated a potential selection bias by indication.
KARAKTERISTIK TANIN DARI EKSTRAK KULIT KAYU LEDA (Eucalyptus deglupta Blume.)
Authors: Awaliyan H. M. Rakhmat , Rosamah Enih , Sukaton Edi 
Published: January 2019

Kulit kayu yang mulanya merupakan limbah industri perkayuan mulai menjadi pusat perhatian. Hal ini dikarenakan kulit kayu banyak memiliki potensi yang dapat dimanfaatkan, selain jumlahnya yang kian meningkat juga ketersediaannya berkesinambungan. Ekstraktif merupakan salah satu potensi yang terkandung dalam kulit kayu yang dapat diperoleh dengan cara ekstraksi. Tanin dapat digunakan untuk berbagai keperluan seperti bahan pengawet, bahan penyamak, bahan perekat, bahan pewarna, bahan farmasi atau bahan industri kimia lainnya. Penelitian ini bertujuan untuk mengetahui kandungan ekstrak yang terdapat pada kulit kayu Eucalyptus deglupta Blume dan untuk mengetahui sifat fisik dan kimia serta kereaktifan tanin yang dihasilkan.Penelitian ini menggunakan 4 macam pelarut yang berbeda untuk menghasilkan ekstrak. Serbuk kulit E. deglupta diekstrak dengan menggunakan pelarut air, pelarut Na2CO3 0,5%, pelarut Urea 0,5% dan pelarut lindi hitam dimana perbandingan pelarut dan serbuk kulit 1 : 5. Hasil ekstraksi menghasilkan nilai rataan rendemen bervariasi yang nilainya berturut-turut sebesar 9,650%, 16,543%, 9,675% dan 28,137% dengan nilai rataan kadar padat berturut-turut sebesar 2,975%, 5,642%, 3,399% dan 9,869%.
STRATEGI DAN PROGRAM PENGUATAN DAYA SAING BARANG KAYU DAN HASIL HUTAN DI KOTA TARAKAN
Authors: Karmini Karmini 
Published: January 2019

Produk-produk industri kecil dan menengah (IKM) yang tergolong dalam kelompok barang kayu dan hasil hutan di Kota Tarakan memiliki daya saing yang tinggi. Namun daya saing tersebut masih dapat ditingkatkan serta perlu dikuatkan, karena adanya persaingan dalam pemasaran produk yang dihasilkan oleh industri pengolahan yang berada di dalam dan di luar Kota Tarakan. Tujuan dari studi ini adalah untuk merumuskan strategi dan program penguatan daya saing barang kayu dan hasil hutan di Kota Tarakan, Provinsi Kalimantan Utara. Studi dilaksanakan pada bulan September hingga Desember 2015. Penelitian ini mengumpulkan data primer dan sekunder. Analisis Kekuatan, Kelemahan, Peluang, dan Ancaman (Strengths, Weakness, Opportunities, and Threats/SWOT) digunakan untuk menganalisis data. Daya saing barang kayu dan hasil hutan di Kota Tarakan berada pada kuadran agresif. Strategi penguatan daya saing barang kayu dan hasil hutan antara lain peningkatan kemampuan IKM dalam memperoleh bahan baku, modal usaha, manajemen produksi dan keuangan, pemasaran, dan akses terhadap kegiatan pembinaan. Program penguatan daya saing barang kayu dan hasil hutan antara lain program peningkatan ketersediaan hasil hutan baik kayu dan non kayu, aksesibilitas ke lembaga keuangan, dan pembinaan manajemen produksi dan manajemen usaha, serta program pengembangan pasar di dalam dan luar negeri bagi produk-produk IKM.
KOMPOSISI JENIS TUMBUHAN BAWAH DI LAHAN REVEGETASI PASCA TAMBANG BATUBARA
Authors: Setiawan Krisna Adib , Sutedjo Sutedjo , Matius Paulus 
Published: January 2019

Salah satu komponen dari ekosistem hutan hujan tropis adalah tumbuhan bawah. Tumbuhnya secara alami tumbuhan bawah di lahan pasca tambang batubara akan membantu dalam proses memulihkan lahan hutan yang terganggu. Penelitian ini bertujuan untuk mengetahui kondisi tumbuhan bawah dan jenis pionir alami di lahan pasca tambang batubara dalam hal kekayaan jenis, keragaman jenis. Pengumpulan data dilakukan dengan menggunakan metode garis berpetak di lahan revegetasi. Hasil inventarisasi diluar lahan revegetasi dijumpai 71 jenis tumbuhan bawah, sedangkan di lahan revegetasi dijumpai 43 jenis tumbuhan bawah. Dari kedua lokasi penelitian, jenis tumbuhan bawah di lahan sekeliling lokasi penelitian dijumpai lebih banyak. Jika dibandingkan dengan data rona awal, jenis tumbuhan bawah lebih beragam pada saat penelitian dilakukan. Kondisi tersebut diduga karena tempat penelitian sebelum dilakukan penambangan merupakan hutan sekunder bekas hutan produksi yaitu Hutan Produksi Terbatas (HPT) dan Hutan Tanaman Industri (HTI). Di lahan revegetasi terdapat 4 jenis tumbuhan pionir yaitu Homalanthus populneus (Geiseler) Pax., Macaranga gigantea (Rchb.f. & Zoll.) Muell.Arg.,Macaranga tanarius (L.) Muell.Arg., dan Trema orientalis L. (Blume). Lahan pasca tambang batubara merupakan lahan yang mengalami gangguan berat, serta merupakan komunitas yang terkendali oleh manusia, sehingga memiliki keragaman jenis yang rendah.
SIFAT KIMIA AIR OBYEK WISATA ALAM GUNUNG RIAN DI KABUPATEN TANA TIDUNG, KALIMANTAN UTARA
Authors: Kurniawan Mohammad Irwan , Kasiman Karyati 
Published: January 2019

The management of tourism sector needs to control environment quality, such as potency of water pollution. The objective of this study was to know the water chemical properties in ecotourism area of Rian Mountain, District of Tana Tidung, Province of North Kalimantan. The water samples were taken at two sampling points, such as waterfall of Rian Mountain and Rian River. The tested water chemical properties were pH, dissolved oxygen (DO), sulphate (SO4), nitrite (NO2-N), biological oxygen demand (BOD5), chemical oxygen demand (COD), iron (Fe), manganese (Mn), and lead (Pb). The result showed that the water chemical properties in two sampling points based on Regulation of East Kalimantan Governor No. 02/2011 about The Management of Water Quality and Water Pollution Control are included to Class I that is can be used to raw water for drinking water, and/or for the other purposes that required similar water quality to that purpose. Beside for potencial ecotourism area, tourism object of Rian Muntain in Tana Tidung can be alternative of clean water source to be consumed safely by the people who live in the area, because until now they do not receive water pipe facilities of MunicipalWater Works (PDAM) yet.
ANALISIS WAKTU KERJA PENGUKURAN TINGGI POHON MENGGUNAKAN KLINOMETER DAN HAGAMETER
Authors: Sari Diah Rakhmah , Ariyanto Ariyanto 
Published: January 2019

Tree height measurement is one part of the inventory activity of standing trees before logging which requires a relatively long time and quite expensive costs, so it needs to use a more productive measuring instrument. There are several commonly used tree height measuring instruments, including the clinometer and hagameter. This study aim is to determine the working time of measuring tree height with clinometer and hagameter. The research method used was to determine the sample tree randomly, then measured the height of each tree with the clinometer and hagameter. In addition, it also calculates the length of time the measurement of the height of each instrument by recording the start and finish time of each measurement activity carried out. The results showed that measuring the height of a tree using clinometer takes 0.68 minutes per tree in average, and using a stick meter aid takes 1.18 minutes in average, and by using haga with a scale board aids takes 0.88 minutes per tree in average. Thus the measurement of tree height by using a clinometer is faster than using haga, while measuring the height of a tree using a hagameter with a scale board is faster than a meter.
The Relationship Between Sleep Quality and Lifestyle of the Elderly
Authors:   Department of Physical Education and Sports Science, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran., Taheri Morteza , Irandoust Khadijeh ,   Department of Physical Education and Sports Science, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran.
Published: January 2019

Objectives: Elderly lifestyle and factors such as physical activity, sleep quality, and nutritional patterns affect quality of life. The purpose of this study was to determine the relationship between sleep quality and elderly lifestyle with an emphasis on physical activity. Methods & Materials: A descriptive-analytic research method was used in which 130 elderly women aged 60-70 years old in Qazvin City in 1397 at the Sports and Health Consultation Center of Sports and Youth Department of Qazvin Province were selected by available sampling method. The nutritional analysis of the subjects was evaluated before the tests to control the effect of food intake on the results using N4 software. The sleep and physical activity recording device (Actiwatch-8) was used to collect data. Pearson correlation coefficient was used for data analysis. Results: The results of the study showed that there was a significant relationship between physical activity with sleep duration (P=0.04), awakening bouts (P=0.038), actual sleep (P=0.003) and time in bed (P=0.035). Conclusion: According to the results, the sleep patterns have a direct relationship with physical activity behavior; therefore, it is recommended to increase the duration of activity in order to improve the quality of sleep in the elderly.
PENGARUH PENDAMPINGAN OSOC TERHADAP KEPUASAN IBUHAMIL TRIMESTER III
Authors: Jannah Muliatul , Meiranny Arum 
Published: January 2019

Kepuasan ibu hamil saat ini menjadi salah satu fokus utama dalam layanan kesehatan maternal dan bidan harus mampu meningkatkan kepuasan tersebut. Salah satunya dengan pendampingan metode OSOC, yaitu pendampingan selama kehamilan, persalinan, nifas, bayi baru lahir sampai keluarga berencana agar kesehatan ibu dan bayi meningkat. Penelitian ini bertujuan untuk mengetahui pengaruh pendampingan OSOC terhadap kepuasan ibu hamil trimester III di Puskesmas Kabupaten Kendal. Penelitian ini merupakan kuasi eksperimental dengan non equivalent control group design. Sampel penelitian ini sebanyak 124 ibu hamil trimester III. Subjek penelitian dibagi menjadi kelompok intervensi dan kontrol. Pada kelompok intervensi, diberikan intervensi berupa pendampinganOSOC, sedangkan kelompok kontrol diberi asuhan kehamilan konvensional. Penelitian dilaksanakan Bulan Juli-September 2018. Rancangan analisis menggunakan Chi Square. Hasil penelitian menunjukkan bahwa terdapat pengaruh pendampingan ibu hamil dengan OSOC terhadap kepuasan, yaitu sebesar 4,741.Simpulan penelitian ini adalah terdapat pengaruh pendampingan OSOC terhadap kepuasan ibu hamil trimester III.
Percepción de la implementación del Currículo de Matemática por docentes ecuatorianos de la zona 9
Authors: Moncayo-Morales Fernando Polivio 
Published: January 2019

El nuevo Currículo del 2016, del sistema educativo Ecuatoriano, promocionado por el Ministerio de Educación, ofrece ser un currículo sólido, bien fundamentado, técnico y coherente, sin embargo la presente investigación aborda el criterio de los docentes, considerando como punto inicial la socialización durante el proceso de elaboración, la pertinencia y eficacia de los cursos masivos que el Estado ecuatoriano propició previo al proceso de aplicación. Como aspecto destacado en este estudio es analizar lo sencillo o complejo que los docentes perciben la selección de contenidos, el desarrollo de destrezas con criterio de desempeño en el aula, mediante una investigación con enfoque cuantitativo, se utilizó como método de recopilación de datos una encuesta. Entre los resultados más destacados y novedosos se encuentran que los docentes del área de Matemática sugieren cambios en la estructura del actual currículo y que el curso de inducción fue poco satisfactorio.
Peningkatan Pertumbuhan dan Hasil Padi Sawah Organik dengan Berbagai Macam Aplikasi Pupuk Hijau Glirisidia
Authors: Winarni Marti 
Published: January 2019

The object of the study was to obtain the types of application of Glirisidia green manures on the growth and yield of organic rice lowland. The experimental pot experiment was carried out in a randomized block design consisting of one factor and three replications. The treatment factor was 10 various application of Glirisidia leaves. The treatments are: 100% fresh Glirisidia leaves + 0% compost; 60% fresh Glirisidia leaves + 40% compost; 40% fresh Glirisidia leaves + 60% compost; 100% wind-dried Glirisidia leaves + 0% compost; 60% of wind-dried Glirisidia leaves + 40% compost; 40% wind-dried Glirisidia leaves + 60% compost; 100% sun-dried Glirisidia leaves + 0% compost; 60% of the sun-dried Glirisidia leaves + 40% of compost; 40% of the sun-dried Glirisidia leaves + 60% compost; and 0% Glirisidia leaves + 100% compost. The results showed that the various application of Glirisidia leaves increased the grain yield 34, 09% compared to the application of 0% Glirisidia leaf + 100% compost. The grain/ hill of yield could be improved by application of 100% fresh Glirisidia leaves + 0% compost (164,47 g grain/hill), 100% of wind-dried Gliricidia leaves (165,55 g grain/ hill) + 0% compost, or 100% sun-dried Gliricidia leaves + 0% compost (169,14 g grain/ hill). Keywords—: organic rice lowland; green manure; various application of Glirisidia leaves.
Shadow Imaging of Transiting Objects
Authors: Sandford Emily , Kipping David 
Published: January 2019

Abstract
We consider the problem of inferring the shape of a transiting object’s silhouette from its light curve alone, without assuming a physical model for the object. We model the object as a grid of pixels which transits a star; each pixel has an opacity, ranging from transparent to opaque, which we infer from the light curve. We explore three interesting degeneracies inherent to this problem, in which markedly different transiting shapes can produce identical light curves: (i) the “flip” degeneracy, by which two pixels transiting at the same impact parameter on opposite sides of the star’s horizontal midplane generate the same light curve; (ii) the “arc” degeneracy, by which opacity can be redistributed along the semicircular arc of pixels which undergoes ingress or egress at the same time without consequence to the light curve; and (iii) the “stretch” degeneracy, by which a wide shape moving fast can produce the same light curve as a narrow shape moving more slowly. By understanding these degeneracies and adopting some additional assumptions, we are able to numerically recover informative shadow images of transiting objects, and we explore a number of different algorithmic approaches to this problem. We apply our methods to real data, including the TRAPPIST-1c/e/f triple transit and two dips of Boyajian’s Star. We provide Python code to calculate the transit light curve of any grid and, conversely, infer the image grid which generates any light curve in the software package accompanying this paper, EightBitTransit (https://github.com/esandford/EightBitTransit).