bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling of Climate Change Impact on Water Availability in Metropolitan Mamminasata, Indonesia
Authors: Barkey R A , Soma A S , Nursaputra M , Mappeasse M F 
Published: August 2019

Abstract
Metropolitan Mamminasata is a National Strategic Area in South Sulawesi Province, Indonesia enacted based on Presidential Regulation Number 55 of 2011 on the spatial plan of Makassar, Maros, Sungguminasa, and Takalar urban areas. The development of these areas as central urban areas makes these areas are very prone to issues of water resilient. Eleven watersheds are affecting the water system in these areas: Jeneberang, Tallo, Maros, Bonelengga, Tabaringan, Lepa-Lepa, Paleko, Saro, Galesong, Pamukkulu, and Cikoang watersheds. The impact of climate change coincides with the change of land use affecting the availability of water in the area. Therefore, this study was conducted to find out the impact of climate change and land use on the availability of water at watersheds affecting the Metropolitan Mamminasata areas. The analysis was done by using Soil model and Water Assessment Tools (SWAT software). The data on climate was analyzed by using data on global weather climate of the 1987-1996 period (past condition) and 2004-2013 period (actual condition) and climate change projection of the 2035s period using RCP 4.5 Model CSIRO Mk3.6.0. Moreover, the data on land use analyzed was of 1996 and 2015. The results of the study indicate that land use in the study area had changed a lot from 1996 to 2015. This change decreased total forest area in watersheds in Metropolitan Mamminasata around 2,000 hectares (42,803.02 ha become 40,815.85 ha) and improved established areas such as settlement, agriculture, mining, and paddy field to 84,79% of the total watershed areas. The change of land cover has an interesting interaction with the climate change condition especially related to the availability of water in the study area. The SWAT model results explain the availability of water in 1987-1996 period as much as 1,682.55 million m3/year and in the 2004-2013 period decreased as much as 11.2% that is 1,485.30 million m3/year. The results of future water availability in the period of 2035s projected total potential water increased, but the potential increased in the wet month and decreased significantly in dry months, comparing to the actual condition of availability of water. This condition illustrates the change of land use, and climate contributes to the level of the quantity of water availability in several watersheds in Metropolitan Mamminasata. The planning of land use in the spatial plan is necessary to be applied so that the continuity of water availability is sustained every year to satisfy the need for water to fellow the increasing number of community.
Evaluating Nature Tourism Destination Potentiality in Samosir Regency using Remote Sensing and GIS
Authors: Susanti R , Ramadhani Y H , Harimurti M 
Published: August 2019

Abstract
Samosir regency is one of the national tourism destinations that has many tourist attractions for both domestic and foreign tourists. The management of sustainable tourism destination requires inventory of tourism assets. Inventory of tourism assets can be determined through natural resources condition in tourism area. Land cover monitoring become useful information to determine natural resources condition in tourism area. Remote sensing technology can be used to monitor land cover changes quickly, accurately and effectively. This research uses a method of digital land cover classification with object-based image analysis (OBIA) approach, because this method effectively used in high resolution image with true colour (RGB). The overall accuracy value obtained from land cover classification using the OBIA approach is 75,4 %. This study aims to analyze the potential of tourist attractions using land cover data as the determinants of physical characteristics besides tourist attractions in addition to attractions accessibility and facilities. Determination of tourism potential is obtained by looking at the relationship between the tourism site physical characteristics with the attraction of a tourist object then categorized using the scoring method. the result of multiple regression analysis obtained by correlation coefficient is R = 0,832, which means there is relationship between facility variable, land cover, and accessibility to the number of visitors in Samosir regency. Tourist attraction potential of Samosir regency is divided into three that is high, middle and low potential tourist attraction. The level of potential tourism object categories is expected to be used in the development of tourism planning in Samosir District to become a sustainable tourism destination.
Specification of Map Generalization from Large Scale to Small Scale Based on Existing Data
Authors: Susetyo D B , Hidayat F 
Published: August 2019

Abstract
Nowadays, the up-to-date and consistent digital spatial information is highly expected by the users. The kind of mapping method development which offers the potential to meet the high expectations is automatic map generalization. In Indonesia map generalization was only implemented in medium and small scale, and has never been done from large scale. This research aims as a beginning in map generalization from large scale by looking at the condition of existing data at all three levels of scale. Therefore, the data selected must be available on large, medium, and small scale. In this study, Bogor is chosen because it had been mapped on a scale of 1:5,000; 1:25,000; and 1:250,000. These operations used are a) selection, b) classification, c) amalgamation, d) aggregation, and e) simplification. The feature studied in this research is building. From this research, we can determine generalization pattern from scale of 1:5,000 to scale of 1:25,000 and 1:250,000 for building feature, so it can be used as prototype design in building generalization from large scale to medium and small scale.
Spatial Modelling of Deforestation Based on Social Driving Force in South Sulawesi and West Sulawesi from 1990 to 2016
Authors: Rijal S , Nismayani  , Mahbub M A S , Pachri H , Nurmiaty  , Arif S 
Published: August 2019

Abstract
Deforestation is a permanent change of forest cover area to non-forest cover area. Social factors contribute more to the occurrence of deforestation, so this study was directed to examine the social factors that drive deforestation. Research location selected based on the key vulnerability of deforestation profiles. This study only used moderately vulnerability and vulnerability profile. Data analysis in this research using PCA (Principal Component Analysis) Method. The results explained that the Spatial Deforestation Model in South Sulawesi and West Sulawesi have differences based on the vulnerability profile. The dominant deforestation profiles affected were population density, productive age and employment. Population density affects deforestation because the site is always experiencing an increase in population and is not balanced with the extent of its territory, especially on vulnerable profiles. Productive age is very influential and increasing. The employment is also one of the most influencing of deforestation. The field of education itself does not give a significant effect. The spatial model of deforestation based on social factors in South Sulawesi shows that in the same profile different influences were found. In West Sulawesi, social involvement tends to be the same for each profile. The influence of population, productive age and availability of regions has a significant influence on the incidence of deforestation.
Development of National Forest/Land Fire Monitoring System Using Remote Sensing Satellite Data (Terra/Aqua Modis and SNPP) by Automation and Nearly Real-time.
Authors: Indradjad A , Sunarmodo W , Salyasari N , Pratiknyo B 
Published: August 2019

Abstract
Hotspot monitoring system using remote sensing satellite data such as Terra/Aqua Modis and SNPP VIIRS. In order to manage national natural disaster (such as forest/land fire disaster), accurate-real time-accessible data and information are required. In this case the use of remote sensing satellites data is use for the monitoring of natural disasters, especially forest/land fires that occur very massive need monitoring in real time and up to date. Information systems for monitoring of forest/land fires, can be built using remote sensing data of Terra/Aqua Modis and SNPP satellites that continuously monitor the condition of the land/forest by photographing the Indonesian territory respectively four times a day. The hotspot data requirement is 30 minute after the reception in ground station. The built system consists of the reception, processing, cataloguing and dissemination data, in order to fit the requirement the system need to be automation. The data receiving process is done at Parepare and Rumpin ground stations, followed by sending data to Pekayon in real time. Data processing is done in Pekayon using automated software open source module. Furthermore, data cataloguing is built using spatial and numerical based databases. The appearance system is built interactively with web-based online and mobile, user can do searching hotspot information based on location, degree of trust and time of incident. The monitoring system of forest / land fires that have been built have been published and utilized nationally, especially the BNPB in the context of the prevention and mitigation of forest / land fire disasters in Indonesia. Users can access through the website http://modis-catalog.lapan.go.id or can download android-based mobile app “Hotspot LAPAN”. It is expected that with online and mobile web based online and mobile fire monitoring system, it can be used for the prevention and mitigation of forest/land fire disaster in Indonesia.
Incremental Improvement of High resolution Satellite Imagery For Participatory Mapping in Land Registration
Authors: Andri H , Sella N , Alfita P , Putri R , Winna P P , Lasmi R , Ratri W , Rani A 
Published: August 2019

Abstract
Fit for purpose land administration (FFP-LA) has a purpose to inventory all of the land parcels. One of the methods in fit for purpose land administration is participatory mapping. Participatory mapping involves the people in the area mapping to create land’s parcel map. The people create a map with their knowledge about spatial objects in their area using a satellite image with high-resolution or aerial photo. The purpose of participatory mapping is to create a full land parcels map that has been validated for geometery boundaries and features by the owner or the people around it. But in some circumstance, the data in that map cannot be an inut data for land administration, cause there is some standard for satellite image with high-resolution or aerial photo that should be followed. The standard was attached in Government’s Law no. 24/1997 and The Ministry of Agrarian Affair’s Law no. 3/1997. In this research, incremental improvement for the high-resolution satellite imagery with some constraints, that is low cost, fast and good enough output and there will analyse a sample of output participatory mapping using high-resolution satellite imagery.
Determinants of Increased Central Excess Pressure in Dialysis: Role of Dialysis Modality and Arteriovenous Fistula
Authors: Paré Mathilde , Goupil Rémi , Fortier Catherine , Mac-Way Fabrice , Madore François , Marquis Karine , Hametner Bernhard , Wassertheurer Siegfried , Schultz Martin G , Sharman James E , Agharazii Mohsen 
Published: August 2019

AbstractBACKGROUNDArterial reservoir-wave analysis (RWA)—a new model of arterial hemodynamics—separates arterial wave into reservoir pressure (RP) and excess pressure (XSP). The XSP integral (XSPI) has been associated with increased risk of clinical outcomes. The objectives of the present study were to examine the determinants of XSPI in a mixed cohort of hemodialysis (HD) and peritoneal dialysis (PD) patients, to examine whether dialysis modality and the presence of an arteriovenous fistula (AVF) are associated with increased XSPI.METHODIn a cross-sectional study, 290 subjects (232 HD and 130 with AVF) underwent carotid artery tonometry (calibrated with brachial diastolic and mean blood pressure). The XSPI was calculated through RWA using pressure-only algorithms. Logistic regression was used for determinants of XSPI above median. Through forward conditional linear regression, we examined whether treatment by HD or the presence of AVF is associated with higher XSPI.RESULTSPatients with XSPI above median were older, had a higher prevalence of diabetes and cardiovascular disease, had a higher body mass index, and were more likely to be on HD. After adjustment for confounders, HD was associated with a higher risk of higher XSPI (odds ratio = 2.39, 95% confidence interval: 1.16–4.98). In a forward conditional linear regression analysis, HD was associated with higher XSPI (standardized coefficient: 0.126, P = 0.012), but on incorporation of AVF into the model, AVF was associated with higher XSPI (standardized coefficient: 0.130, P = 0.008) and HD was excluded as a predictor.CONCLUSIONThis study suggests that higher XSPI in HD patients is related to the presence of AVF.
Stomatal anatomy coordinates leaf size with Rubisco kinetics in the Balearic Limonium
Authors: Conesa Miquel À , Muir Christopher D , Molins Arantzazu , Galmés Jeroni 
Published: August 2019

Abstract
Trait integration arises through both selection on functional coordination and shared developmental pathways. Different anatomical components must both work well and develop together to generate individuals with the appropriate physiology to survive and reproduce in their environment. In this study, we used a common garden experiment and Bayesian multilevel models to test whether stomatal anatomy coordinates leaf gas exchange, Rubisco kinetics, and leaf size across 10 closely related species of Limonium from the Balearic Islands. The results indicate that the anatomical determinants of maximum stomatal conductance, stomatal density and size, were functionally coordinated with Rubisco kinetics – species whose stomatal anatomy was correlated with low stomatal conductance have evolved Rubisco enzymes better adapted to low operational chloroplastic CO2 concentrations. Lower stomatal density was associated with greater leaf size, which can be explained by a greater proportion of pavement cells in large-leaved species. These results suggest that both selection for functional coordination (stomata and Rubisco kinetics) and shared development pathways (stomatal density and leaf area) likely shape patterns of trait integration between species.
Fractionation of Adipose Tissue Procedure With a Disposable One-Hole Fractionator
Authors: Van Dongen Joris A , Gostelie Olivier F E , Vonk Lucienne A , De Bruijn Julia J , Van Der Lei Berend , Harmsen Martin C , Stevens Hieronymus P 
Published: August 2019

AbstractBackgroundAdipose tissue has been widely used in regenerative surgery for its therapeutic potential. This potential is often ascribed to the stromal vascular fraction (SVF), which can be mechanically isolated. Mechanical isolation results in an SVF that retains intact cell-cell communication including extracellular matrix and is therefore named tissue-SVF (tSVF).ObjectivesThe aim of this study was to evaluate a new disposable 1-hole fractionator for fractionation of adipose tissue (FAT), and compare this new device with the existing reusable 3-hole fractionator.MethodsThe composition of tSVF obtained via the 1-hole fractionator was histologically and histochemically compared to unprocessed adipose tissue. The number of viable nuclear cells in tSVF obtained by the 1-hole and 3-hole fractionators as well as unprocessed adipose tissue were compared after enzymatic isolation and tested for colony-forming capacity. Flow cytometry was used to compare different cell compositions based on surface marker expression between tSVF isolated by the two types of fractionators.ResultsFractionation of adipose tissue with the 1-hole fractionator condenses vasculature and extracellular matrix by disrupting adipocytes. The number of viable nuclear cells in tSVF obtained with the two fractionators was comparable and significantly higher than unprocessed lipoaspirate. Furthermore, tSVF isolated by both fractionators showed similar cell compositions and comparable colony-forming capacities.ConclusionsFAT with a disposable 1-hole fractionator effectively isolates tSVF with a cell count and cell composition comparable to the fraction obtained with the 3-hole reusable fractionator. The disposable 1-hole fractionator, however, is safer and more user friendly.
Androgens are essential for epithelial cell recovery after efferent duct ligation in the initial segment of the mouse epididymis†
Authors: Kim Bongki , Breton Sylvie 
Published: August 2019

Abstract
Efferent duct ligation (EDL) induces epithelial cell degeneration followed by regeneration in the epididymal initial segment. We tested here the role of androgens in the recovery phase. EDL was performed at post-natal weeks (PNW) 3, 4, 5, 6, and 7, and apoptotic and proliferating epithelial cells were quantified 24 h, and at days 2 and 2.5 post-EDL, respectively. A progressive increase in the number of apoptotic basal cells (BCs) and principal cells (PCs) was detected from PNW3 to 6, 24 h after EDL. Two days after EDL, no increase in proliferating BCs and PCs was observed at PNW3 and 4, despite the induction of apoptosis by EDL. A progressive increase in the number of proliferating BCs was then observed from PNW5 to 6, while the number of proliferating PCs remained low. 2.5 days after EDL, the number of proliferating BCs and PCs remained low at PNW3, 4, and 5, but a marked increase in the number of proliferating PCs was observed at PNW6. Flutamide pretreatment for 3 weeks followed by EDL at PNW7 dramatically decreased the number of proliferating BCs on EDL day 2, and the number of proliferating PCs on EDL day 2.5, compared to controls. We conclude that (1) BCs are the first to show recovery after EDL, followed by PCs; (2) androgens are essential for BC and PC repair after injury in the postpubertal epididymis; and (3) the prepubertal epididymis lacks repair ability following injury.
Expression and functional analyses of ephrin type-A receptor 2 in mouse spermatogonial stem cells†
Authors: Morimoto Hiroko , Kanatsu-Shinohara Mito , Orwig Kyle E , Shinohara Takashi 
Published: August 2019

AbstractSpermatogonial stem cells (SSCs) undergo continuous self-renewal division in response to self-renewal factors. The present study identified ephrin type-A receptor 2 (EPHA2) on mouse SSCs and showed that supplementation of glial cell-derived neurotrophic factor (GDNF) and fibroblast growth factor 2 (FGF2), which are both SSC self-renewal factors, induced EPHA2 expression in cultured SSCs. Spermatogonial transplantation combined with magnetic-activated cell sorting or fluorescence-activated cell sorting also revealed that EPHA2 was expressed in SSCs. Additionally, ret proto-oncogene (RET) phosphorylation levels decreased following the knockdown (KD) of Epha2 expression via short hairpin ribonucleic acid (RNA). Although the present immunoprecipitation experiments did not reveal an association between RET with EPHA2, RET interacted with FGFR2. The Epha2 KD decreased the proliferation of cultured SSCs and inhibited the binding of cultured SSCs to laminin-coated plates. The Epha2 KD also significantly reduced the colonization of testis cells by spermatogonial transplantation. EPHA2 was also expressed in human GDNF family receptor alpha 1-positive spermatogonia. The present results indicate that SSCs express EPHA2 and suggest that it is a critical modifier of self-renewal signals in SSCs.
The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility†
Authors: Holcomb Richard J , Oura Seiya , Nozawa Kaori , Kent Katarzyna , Yu Zhifeng , Robertson Matthew J , Coarfa Cristian , Matzuk Martin M , Ikawa Masahito , Garcia Thomas X 
Published: August 2019

Abstract
High-throughput transcriptomics and proteomics approaches have recently identified a large number of germ cell–specific genes with many that remain to be studied through functional genetics approaches. Serine proteases (PRSS) constitute nearly one-third of all proteases, and, in our bioinformatics screens, we identified many that are testis specific. In this study, we chose to focus on Prss44, Prss46, and Prss54, which we confirmed as testis specific in mouse and human. Based on the analysis of developmental expression in the mouse, expression of all four genes is restricted to the late stage of spermatogenesis concomitant with a potential functional role in spermiogenesis, spermiation, or sperm function. To best understand the male reproductive requirement and functional roles of these serine proteases, each gene was individually ablated by CRISPR/Cas9-mediated ES cell or zygote approach. Homozygous deletion mutants for each gene were obtained and analyzed for phenotypic changes. Analyses of testis weights, testis and epididymis histology, sperm morphology, and fertility revealed no significant differences in Prss44, Prss46, and Prss54 knockout mice in comparison to controls. Our results thereby demonstrate that these genes are not required for normal fertility in mice, although do not preclude the possibility that these genes may function in a redundant manner. Elucidating the individual functional requirement or lack thereof of these novel genes is necessary to build a better understanding of the factors underlying spermatogenesis and sperm maturation, which has implications in understanding the etiology of male infertility and the development of male contraceptives.
Reversal of Age-Related Changes in Cortical Sound-Azimuth Selectivity with Training
Authors: Cheng Yuan , Zhang Yifan , Wang Fang , Jia Guoqiang , Zhou Jie , Shan Ye , Sun Xinde , Yu Liping , Merzenich Michael M , Recanzone Gregg
H , Yang Lianfang , Zhou Xiaoming 
Published: August 2019

Abstract
The compromised abilities to understand speech and localize sounds are two hallmark deficits in aged individuals. Earlier studies have shown that age-related deficits in cortical neural timing, which is clearly associated with speech perception, can be partially reversed with auditory training. However, whether training can reverse aged-related cortical changes in the domain of spatial processing has never been studied. In this study, we examined cortical spatial processing in ~21-month-old rats that were trained on a sound-azimuth discrimination task. We found that animals that experienced 1 month of training displayed sharper cortical sound-azimuth tuning when compared to the age-matched untrained controls. This training-induced remodeling in spatial tuning was paralleled by increases of cortical parvalbumin-labeled inhibitory interneurons. However, no measurable changes in cortical spatial processing were recorded in age-matched animals that were passively exposed to training sounds with no task demands. These results that demonstrate the effects of training on cortical spatial domain processing in the rodent model further support the notion that age-related changes in central neural process are, due to their plastic nature, reversible. Moreover, the results offer the encouraging possibility that behavioral training might be used to attenuate declines in auditory perception, which are commonly observed in older individuals.