bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marketing Publicitario Mipymes.
Authors: Velasteguí Efraín , Guamangate Marco 
Published: January 2019

El trabajo investigativo se orientó al diseño de un plan de marketing para mejorar la gestión de ventas mediante la aplicación de estrategias de marketing, publicidad, promoción e implementación de un plan de marketing el desarrollo de la investigación y el avance de la tecnología ha permitido el crecimiento en distintas áreas del conocimiento como la medicina, ingeniería, educación; entre otras de las cuales se resalta en entorno web que ha revolucionado el ámbito empresarios actualizado la forma de hacer negocios de manera presencial a distintas a través de medios de comunicaciones que favorecen la interacción entre empresas y mercado llegando a más clientes las existencia de la sociedad contemporánea denotan una necesidad imperiosa de las pymes a incursionaren el mundo informática para explorar sus potencialidades con la finalidad de crear un volar agregado a toda organización que marque la diferencias entre el éxito y el fracaso; entre los medios se cita a los redes sociales debido a que son las más usadas gracias a que poseen una mayor versatilidad que facilita la empresa realizar acciones remotas como darse a conocer de forma indirecta una estrategia de marketing que fomente al desarrollo empresarial de las pymes en el ecuador para fundamentar el estudio se realizó esta investigación buscar dar a conocer las virtudes que la redes prestan a las empresas en el entorno socioeconómico del ecuador las pymes son todas pequeñas y medianas empresas que se dedican a verde sus productos o presta servicios a cambio de remuneración en una empresa capaz de influir en la economía local o nacional.
Estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo local del cantón Santo Domingo, provincia de Santo Domingo de los Tsáchilas.
Authors: Guamán Chávez Ramiro Enrique , Tinoco Díaz Evelyn Karina , Castro Celi Verónica Janneth , Guanuchi Pucha Lisseth Marisol 
Published: January 2019

Esta investigación relacionada con el estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo local del cantón Santo Domingo, provincia de Santo Domingo de los Tsachilas plante como problema ¿Que incidencia tendría un estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo local del cantón Santo Domingo?, cuyo objetivo general es elaborar un estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo del cantón de Santo Domingo; el mismo que para su ejecución fue necesario la utilización de métodos estratégicos y/o técnicas como la encuesta, entrevista, el análisis, arrojan como resultado del diagnóstico el Plan para la implementación de una granja integral para desarrollar un ciclo óptimo de producción agrícola, avícola y ganadera del cantón Santo Domingo, para el desarrollo local y mejorar la productividad y calidad de vida de productores.
Educação: um processo de humanização
Authors: Chagas Edla Maria Gordiano 
Published: January 2019

O presente trabalho, toma-se como objeto de estudo a contribuição do Orientador Educacional nas relações interpessoais entre o corpo docente, discente e famílias. Com objetivo de analisar a importância da presença do Orientador Educacional nas escolas do grupo SEB - sistema Educacional Brasileiro na Bahia, cujo projeto foi submetido e aprovado pelo Comitê de Ética em Pesquisa da UFBA (Universidade Federal da Bahia). Realizou-se a pesquisa em quatro escolas da Bahia, três no município de Salvador e uma no município de Lauro de Freitas. Optou-se pela abordagem qualitativa exploratória. Assim, foi realizada entrevista semiestruturada como dispositivos de investigação. A partir da questão básica acerca do que pensa o corpo docente, discente e família a respeito do trabalho do Orientador Educacional? Para tanto, buscou-se como marco teórico as contribuições de Grinspun (1994/2010); CONCEIÇÃO, (2010); Giacáglia e Penteado (2010); Morin (2010), com informações atuais e de extrema relevância à temática estudada, proporcionando o enriquecimento da pesquisa com fundamentação científica. Os resultados apontaram que o trabalho da Orientação Educacional no contexto das distintas unidades da escola particular investigada, caracterizou-se por uma dimensão pedagógica muito mais abrangente, tendo suas funções demarcadas e valorizadas. Este profissional possui um caráter mediador junto aos demais educadores, atuando em conjunto com todos os atores da escola para facilitar as relações interpessoais, no resgate de uma ação mais efetiva e reflexiva, visando qualificar a educação nas unidades escolares, tornando-as indivíduos conscientes, reflexivos e respeitosos com as diferenças e coletividade.
The CIDA Variability Survey of Orion OB1. II. Demographics of the Young, Low-mass Stellar Populations*
Authors: Briceño César , Calvet Nuria , Hernández Jesús , Vivas A. Katherina , Mateu Cecilia , Downes Juan José , Loerincs Jaqueline , Pérez-Blanco Alice , Berlind Perry , Espaillat Catherine , Allen Lori , Hartmann Lee , Mateo Mario , Bailey III John I. 
Published: January 2019

Abstract
We present results of our large-scale, optical, multi-epoch photometric survey across ∼180 square degrees in the Orion OB1 association, complemented with extensive follow-up spectroscopy. Our focus is mapping and characterizing the off-cloud, low-mass, pre-main-sequence (PMS) populations. We report 2062 K- and M-type confirmed T Tauri members; 59% are located in the OB1a subassociation, 27% in the OB1b subassociation, and the remaining 14% in the A and B molecular clouds. We characterize two new clusterings of T Tauri stars, the HD 35762 and HR 1833 groups, both located in OB1a not far from the 25 Ori cluster. We also identify two stellar overdensities in OB1b, containing 231 PMS stars, and find that the OB1b region is composed of two populations at different distances, possibly due to the OB1a subassociation overlapping with the front of OB1b. A ∼2 deg wide halo of young stars surrounds the Orion Nebula Cluster, corresponding in part to the low-mass populations of NGC 1977 and NGC 1980. We use the strength of Hα in emission, combined with the IR excess and optical variability, to define a new type of T Tauri star, the C/W class, stars we propose may be nearing the end of their accretion phase, in an evolutionary state between classical and weak-lined T Tauri stars. The evolution of the ensemble-wide equivalent width of Li i
λ6707 indicates a Li depletion timescale of ∼8.5 Myr. Disk accretion declines with an e-folding timescale of ∼2 Myr, consistent with previous studies.
Charged Grains and Kelvin–Helmholtz Instability in Molecular Clouds
Authors: Pandey B. P. , Vladimirov S. V. 
Published: January 2019

Abstract
The presence of dust grains profoundly affects the diffusion of the magnetic field in molecular clouds. When the electrons and ions are well coupled to the magnetic field and charged grains are only indirectly coupled, emergent Hall diffusion may dominate over all the other non-ideal magnetohydrodynamic (MHD) effects in a partially ionized dusty cloud. The low-frequency, long (∼0.01–1 pc) wavelength dispersive MHD waves will propagate in such a medium with the polarization of the waves determined by the dust charge density or the dust size distribution. In the presence of shear flows, these waves may become Kelvin–Helmholtz unstable with the dust charge density or the grain size distribution operating as a switch to the instability. When Hall diffusion time is long (compared to the time over which waves are sheared), the growth rate of the instability in the presence of sub-Alfvénic flow increases with the charge number

on the grain, while it is quenched in the presence of Alfvénic or super-Alfvénic flows. However, when Hall diffusion is fast, the growth rate of the instability depends on the dust charge only indirectly.
Investigating Fragmentation of Gas Structures in OB Cluster-forming Molecular Clump G33.92+0.11 with 1000 au Resolution Observations of ALMA
Authors: Liu Hauyu Baobab , Chen Huei-Ru Vivien , Román-Zúñiga Carlos G. , Galván-Madrid Roberto , Ginsburg Adam , Ho Paul T. P. , Minh Young Chol , Jiménez-Serra Izaskun , Testi Leonardo , Zhang Qizhou 
Published: January 2019

Abstract
We report new ∼1000 au spatial resolution observations of 225 GHz dust continuum emission toward the OB cluster-forming molecular clump G33.92+0.11. On parsec scales, this molecular clump presents a morphology with several arm-like dense gas structures surrounding the two central massive (≳100 M
⊙) cores. From the new higher resolution observations, we identified 28 localized, spatially compact dust continuum emission sources, which may be candidates of young stellar objects (YSOs). Only one of them is not embedded within known arm-like (or elongated) dense gas structures. The spatial separations of these compact sources can be very well explained by Jeans lengths. We found that G33.92+0.11 may be consistently described by a marginally centrifugally supported, Toomre unstable accretion flow that is approximately in a face-on projection. The arm-like overdensities are a natural consequence of the Toomre instability, which can fragment to form YSOs in shorter timescales than the timescale of the global clump contraction. On our resolved spatial scales, there is no evidence yet that the fragmentation is halted by turbulence, the magnetic field, or stellar feedback.
Measurement Accuracy of Inspiraling Eccentric Neutron Star and Black Hole Binaries Using Gravitational Waves
Authors: Gondán László , Kocsis Bence 
Published: January 2019

Abstract
In a recent paper, we determined the measurement accuracy of physical parameters for eccentric, precessing, non-spinning, inspiraling, stellar-mass black hole - black hole (BH–BH) binaries for the upcoming second-generation LIGO/VIRGO/KAGRA detector network at design sensitivity using the Fisher matrix method. Here we extend that study to a wide range of binary masses including neutron star - neutron star (NS–NS), NS–BH, and BH–BH binaries with BH masses up to 110

. The measurement error of eccentricity

at a gravitational-wave (GW) frequency of 10 Hz is in the range

for NS–NS, NS–BH, and BH–BH binaries at a luminosity distance of D

L
if

. For events with masses and distances similar to the detected 10 GW transients, we show that nonzero orbital eccentricities may be detected if

. Consequently, the LIGO/VIRGO/KAGRA detector network at design sensitivity will have the capability to distinguish between eccentric waveforms and circular waveforms. In comparison to circular inspirals, we find that the chirp mass measurement precision can improve by up to a factor of ∼20 and ∼50–100 for NS–NS and NS–BH binaries with BH companion masses ≲40

, respectively. The identification of eccentric sources may give information on their astrophysical origin; it would indicate merging binaries in triple or higher multiplicity systems or dynamically formed binaries in dense stellar systems such as globular clusters or galactic nuclei.
Interaction of Hemispherical Blast Waves with Inhomogeneous Spheres: Probing the Collision of a Supernova Ejecta with a Nearby Companion Star in the Laboratory
Authors: García-Senz Domingo , Velarde Pedro , Suzuki-Vidal Francisco , Stehlé Chantal , Cotelo Manuel , Portillo David , Plewa Tomasz , Pak Arthur 
Published: January 2019

Abstract
Past laboratory experiments at high energy density have provided insights into the physics of supernovae, supernova remnants, and the destruction of interstellar clouds. In a typical experimental setting, a laser-driven planar blast wave interacts with a compositionally homogeneous spherical or cylindrical target. In this work we propose a new laboratory platform that accounts for curvature of the impacting shock and density stratification of the target. Both characteristics reflect the conditions expected to exist shortly after a supernova explosion in a close binary system. We provide details of a proposed experimental design (laser drive, target configuration, diagnostic system), optimized to capture the key properties of recent ejecta–companion interaction models. Good qualitative agreement found between our experimental models and their astrophysical counterparts highlights the strong potential of the proposed design to probe details of the ejecta–companion interaction for broad classes of objects by means of laboratory experiments at high energy density.
Observations of SN 2017ein Reveal Shock Breakout Emission and a Massive Progenitor Star for a Type Ic Supernova
Authors: Xiang Danfeng , Wang Xiaofeng , Mo Jun , Wang Lingjun , Smartt Stephen , Fraser Morgan , Ehgamberdiev Shuhrat A. , Mirzaqulov Davron , Zhang Jujia , Zhang Tianmeng , Vinko Jozsef , Wheeler J. Craig , Hosseinzadeh Griffin , Howell D. Andrew , McCully Curtis , DerKacy James M , Baron E. , Brown Peter , Zhang Xianfei , Bi Shaolan , Song Hao , Zhang Kaicheng , Rest A. , Nomoto Ken’ichi , Tolstov Alexey , Blinnikov Sergei 
Published: January 2019

Abstract
We present optical and ultraviolet observations of nearby Type Ic supernova (SN Ic) SN 2017ein, as well as a detailed analysis of its progenitor properties from both the early-time observations and the prediscovery Hubble Space Telescope (HST) images. The optical light curves started from within 1 day to ∼275 days after explosion, and optical spectra range from ∼2 days to ∼90 days after explosion. Compared to other normal SNe Ic like SN 2007gr and SN 2013ge, SN 2017ein seems to have more prominent C ii absorption and higher expansion velocities in early phases, suggestive of relatively lower ejecta mass. The earliest photometry obtained for SN 2017ein shows indications of shock cooling. The best fit obtained by including a shock-cooling component gives an estimate of the envelope mass as ∼0.02 M
⊙ and stellar radius as 8 ± 4 R
⊙. Examining the pre-explosion images taken with the HST WFPC2, we find that the SN position coincides with a luminous and blue point-like source, with an extinction-corrected absolute magnitude of M

V
∼ −8.2 mag and M

I
∼ −7.7 mag. Comparisons of the observations to the theoretical models indicate that the counterpart source was either a single W-R star or a binary whose members had high initial masses, or a young compact star cluster. To further distinguish between different scenarios requires revisiting the site of the progenitor with HST after the SN fades away.
Rapid Rotation in the Kepler Field: Not a Single Star Phenomenon
Authors: Simonian Gregory V. A. , Pinsonneault Marc H. , Terndrup Donald M. 
Published: January 2019

Abstract
Tens of thousands of rotation periods have been measured in the Kepler fields, including a substantial fraction of rapid rotators. We use Gaia parallaxes to distinguish photometric binaries (PBs; from single stars on the unevolved lower main sequence, and compare their distribution of rotation properties to those of single stars both with and without Apache Point Observatory Galactic Evolution Experiment spectroscopic characterization. We find that 59% of stars with 1.5 day < P < 7 day lie 0.3 mag above the main sequence, compared with 28% of the full rotation sample. The fraction of stars in the same period range is 1.7 ± 0.1% of the total sample analyzed for rotation periods. Both the PB fraction and the fraction of rapid rotators are consistent with a population of non-eclipsing short-period binaries inferred from Kepler eclipsing binary data after correcting for inclination. This suggests that the rapid rotators are dominated by tidally synchronized binaries rather than single stars obeying traditional angular momentum evolution. We caution against interpreting rapid rotation in the Kepler field as a signature of youth. Following up on this new sample of 217 candidate tidally synchronized binaries will help further understand tidal processes in stars.
Water and OH Emission from the Inner Disk of a Herbig Ae/Be Star
Authors: Adams Steven C. , Ádámkovics Máté , Carr John S. , Najita Joan R. , Brittain Sean D. 
Published: January 2019

Abstract
We report the detection of hot H2O and OH emission from the Herbig Ae/Be star HD 101412 using the Cryogenic Infrared Echelle Spectrograph on the Very Large Telescope. Previous studies of Herbig Ae/Be stars have shown the presence of OH around some of these sources, but H2O has proven more elusive. While marginal water emission has been reported in the mid-infrared, and a few Herbig Ae/Be stars show water emission in the far-infrared, water emission near 2.9 μm has not been previously detected. We apply slab models to the rovibrational OH, H2O, and CO spectra of this source and show that the molecules are consistent with being cospatial. We discuss the possibility that the detection of the CO overtone bandhead emission, detection of water emission, and the large line to continuum contrast of the OH lines may be connected to its high inclination and the λ Boö nature of this star. If the low abundance of refractories results from the selective accretion of gas relative to dust, the inner disk of HD 101412 should be strongly dust-depleted, allowing us to probe deeper columns of molecular gas in the disk, enhancing its molecular emission. Our detection of C- and O-bearing molecules from the inner disk of HD 101412 is consistent with the expected presence, in this scenario, of abundant volatiles in the accreting gas.
Théodore Simon (1873-1961). Itinéraire d’un psychiatre engagé pour la professionnalisation des infirmiers et infirmières d’asile
Authors: Klein Alexandre 
Published: January 2019

Célèbre pour avoir créé, avec le psychologue Alfred Binet (1857-1911), la fameuse Échelle métrique de l’intelligence, le psychiatre Théodore Simon (1873-1961) fut aussi, on le sait moins, un acteur central de la professionnalisation des infirmiers et infirmières d’asile en France. Depuis le manuel engagé qu’il publia en 1911 jusqu’à la revue, très explicitement intitulée « L’Infirmier Psychiatrique », qu’il créa en 1953, en passant par l’école spécialisée qu’il fonda puis dirigea de 1946 à 1957 à l’hôpital Maison Blanche de Neuilly-sur-Marne, Simon a œuvré durant toute sa carrière pour la reconnaissance et la formation de ceux qu’il voyait comme de véritables collaborateurs. C’est ce que nous montrerons dans cet article 1 qui se propose, en revenant sur le parcours oublié de ce médecin d’asile militant, de mettre en lumière son engagement en faveur de la professionnalisation du personnel infirmier en psychiatrie.
Le corps personnel. Étude du rôle du corps dans l’élaboration de l’être personnel dans le Traité du caractère et Le Personnalisme d’Emmanuel Mounier
Authors: Lucas Marie-Odile 
Published: January 2019

Le corps est ce par quoi la personne peut advenir, et participant ainsi à l’élaboration de la vie personnelle, il devient ainsi en quelque sorte lui-même personnel. Reflet et porte d’entrée de la personne, il est ce qui permet à la personne également de se donner à connaître, comme de se donner dans la relation sexuelle. Le développement de l’être personnel remet ainsi en cause la vision dualiste du l’homme. Il n’est pas un corps abritant un esprit : il est corps permettant la vie de l’esprit, et esprit irrigant sans cesse le corps.
Identification of Variable and Joining Germline Genes and Alleles for Rhesus Macaque from B Cell Receptor Repertoires
Authors: Zhang Wei , Li Xinyue , Wang Longlong , Deng Jianxiang , Lin Liya , Tian Lei , Wu Jinghua , Tang Chenling , Yang Huanming , Wang Jian , Qiu Ping , Fu Tong-Ming , Saksena Nitin K. , Wang I-Ming , Liu Xiao 
Published: January 2019

Abstract
The rhesus macaque is a valuable preclinical animal model to estimate vaccine effectiveness and is also important for understanding Ab maturation and B cell repertoire evolution responding to vaccination. However, incomplete mapping of rhesus Ig germline genes hinders the research efforts. To address this deficiency, we sequenced the BCR repertoires of 75 Indian rhesus macaques. Using a bioinformatic method that has been validated with BCR repertoire analysis of three human donors, we were able to infer rhesus variable (V) and joint (J) germline alleles. We identified a total of 122 V and 20 J germline alleles, of which 91 V and 13 J alleles were novel, with 40 V novel genes, of which 8 were located at a novel genomic region not, to our knowledge, previously recorded. The novelty of these newly identified alleles was supported by two observations. First, the 50 V and 5 J novel alleles were observed in the whole genome sequencing data of 10 rhesus macaques. Second, using alignment reference including the novel alleles, the mutation rate of the rearranged repertoires significantly declined in nine other irrelevant samples, and all our identified novel V and J alleles were 100%-identity mapped by rearranged repertoire data. These identified novel alleles, along with the previously reported alleles, provide an important reference for future investigations of rhesus immune repertoire evolution in response to vaccination or infection. In addition, the method outlined in our study offers a powerful foundation for the identification of novel Ig alleles in the future.
Characterization of Glucose Transporter 6 in Lipopolysaccharide-Induced Bone Marrow–Derived Macrophage Function
Authors: Caruana Beth T. , Byrne Frances L. , Knights Alexander J. , Quinlan Kate G. R. , Hoehn Kyle L. 
Published: January 2019

Abstract
The polarization processes for M1 versus M2 macrophages are quite distinct in the context of changes in cellular metabolism. M1 macrophages are highly glycolytic, whereas M2 macrophages require a more oxidative nutrient metabolism. An important part of M1 polarization involves upregulation of the glucose transporter (GLUT) GLUT1 to facilitate increased glucose uptake and glycolytic metabolism; however, the role of other glucose transporters in this process is largely unknown. In surveying the Functional Annotation of the Mammalian Genome and Gene Expression Omnibus Profiles databases, we discovered that the glucose transporter GLUT6 is highly upregulated in LPS-activated macrophages. In our previous work, we have not detected mouse GLUT6 protein expression in any noncancerous tissue; therefore, in this study, we investigated the expression and significance of GLUT6 in bone marrow–derived macrophages from wild-type and GLUT6 knockout C57BL/6 mice. We show that LPS-induced M1 polarization markedly upregulated GLUT6 protein, whereas naive macrophages and IL-4–induced M2 macrophages do not express GLUT6 protein. However, despite strong upregulation of GLUT6 in M1 macrophages, the absence of GLUT6 did not alter M1 polarization in the context of glucose uptake, glycolytic metabolism, or cytokine production. Collectively, these data show that GLUT6 is dispensable for LPS-induced M1 polarization and function. These findings are important because GLUT6 is an anticancer drug target, and this study suggests that inhibition of GLUT6 may not impart detrimental side effects on macrophage function to interfere with their antitumor properties.
Anaesthetic management of children with craniopharyngioma
Authors: Moningi Srilata 
Published: January 2019

AbstractThe perioperative management of craniopharyngioma in children is quite challenging not only to the neurosurgeons and anaesthesiologists but also to the oncologists, endocrinologists and intensivists. The various concerns include size of the tumour and its effects on intracranial pressure, vicinity of the tumour to nearby vessels and neural structures, endocrine disturbances, compressive symptoms, paediatric age, obesity-related problems, high recurrence rate of the tumour, undesired effects of radiotherapy, high morbidity and mortality. As anaesthesiologists, we deal with most of the challenges. The success of the outcome depends on the proper identification of the patient, pre-operative optimisation, surgical decision, awareness of the complications, timely intervention and optimal post-operative care.