bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Supermodel Astronaut Challenge: traversing frames of mind
Authors: Glasser Leanne , Young Emily , Sameshima Pauline 
Published: August 2019

Purpose
The Supermodel Astronaut (SMA) Challenge began with a group of women in a graduate class who joined together to take the pledge “I Am Enough.” The goals of the pledge are to practice positive affirmative actions of self-acceptance, self-grace, self-improvement and positive encouragement of oneself and others. The paper aims to discuss this issue.

Design/methodology/approach
The SMA Challenge involves an online video pledge to encourage women and girls to demonstrate their opposition to the promotion of singular ideals of body perpetuated through media. Various individuals and groups have created music videos titled SMA to the soundtrack created by Ellen Tift (the originator of the project).

Findings
Here, framed by Daignault’s (1983) theories on curriculum construction, the authors critically reflect on their support of the idea of the video, but also their apprehension and insecurities in participating in the video production.

Originality/value
From reflections, writings and dialogic discussions, they determined five embodied frames of mind that supported them in traversing the liminal space of new learning: imagining the possible, learning in doing, settling in vulnerability, journeying through empowerment and heightening self-reflection.
An empirical framework to study food labelling fraud: an application to the Italian extra‐virgin olive oil market
Authors: Bimbo Francesco , Bonanno Alessandro , Viscecchia Rosaria 
Published: August 2019

The mislabelling of agricultural and food products is one of the most common types of food fraud. Despite the frequency with which labelling fraud occurs, there is no empirical framework to study its welfare implications, the probability that it may occur, and the measures that can limit its occurrence. We present an empirical framework to study the economic consequences of food labelling fraud in a differentiated products food market. Such framework requires the availability of sales data and the use of an ‘attribute‐space' demand model. The model is applied to the Italian extra‐virgin olive oil market to simulate the occurrence of fraudulent ‘100 per cent Italian' claims. Our results indicate that potential consumer losses due to overpayments for a false claim are higher than manufacturer gains, suggesting that labelling fraud results in welfare losses and not just in welfare transfers. Simulation results indicate that the level of the current administrative fines is not likely to be effective to discourage ‘100 per cent Italian' labelling fraud. Imposing larger fines or other measures negatively affecting a firm's image could be more effective in deterring labelling fraud.
Relationship Among Denture Status, Remaining Teeth Number, and Malnutrition in Patients With Chronic Kidney Disease
Authors: Sevmez Hatice , Bankoğlu Güngör Merve , Yeter Hasan , Erten Yasemin , Elbeg Şehri , Yılmaz Handan 
Published: August 2019

AbstractThe purpose of the present study was to evaluate the relationship among the denture status, number of remaining teeth, and malnutrition in patients with chronic kidney disease (CKD). Seventy‐three patients (43 men/30 women) who required hemodialysis were included in the study. Weight and height, Kt/V, urea reduction ratio, midweek interdialytic weight gain, ultrafiltration volume, and erythropoietin dosage were determined for all patients. Laboratory measurements and predialysis blood samples for biomarkers were collected within the monthly routine tests. Dental examination focused on the denture status and total number of remaining teeth. Denture status were classified into two groups as prosthesis group (patients have prosthesis) and no prosthesis group (patients do not have any kind of prosthesis). And also, patients were assigned to one of four categories based on the number of remaining natural teeth: (i) edentulous, (ii) 1–7 teeth, (iii) 8–19 teeth, and (iv) >20 teeth. The data were statistically analyzed (a = 0.05). Body mass index values were increased in the prosthesis patients. Serum albumin levels of the CKD patients were under the reference value (3.8 g/dL) both in prosthesis and no prosthesis groups. Patients who have eight and more teeth showed higher serum albumin levels, and patients who had 1–7 teeth showed lower serum albumin levels in prosthesis group. CKD patients’ nutritional habits were affected by denture status (having prosthesis or not). The number of the remaining teeth in prosthesis group affected the serum albumin levels of CKD patients.
Effect of Improving Volume Overload on Home Blood Pressure Variability in Hemodialysis Patients
Authors: Chen Ziye , Liu Jing , Sun Fang , Shen Yang , Ma Lijie , Zhou Yilun 
Published: August 2019

AbstractBlood pressure variability is an independent predictor of adverse clinical events in hemodialysis patients. Volume overload is one of the most important factors affecting blood pressure homeostasis. In the present study, we explored the effects of dry weight reduction on home blood pressure variability in volume overload hemodialysis patients. Hemodialysis patients with volume overload had their dry weight gradually decreased under the guidance of bioimpedance methods, which was represented by calf‐bioimpedance ratio (Calf‐BR). Home blood pressure was measured on waking up and at bedtime for 1 week at baseline and at the end of the two‐month study. Coefficient of variation was used to define home blood pressure variability. Thirty‐eight hemodialysis patients had their dry weight significantly decreased from 60.7 ± 11.3 to 59.6 ± 10.7 kg (P = 0.003) accompanied with a significant reduction in calf‐BR (0.828 ± 0.023 vs. 0.786 ± 0.020, P<0.001). The systolic and diastolic blood pressure decreased significantly. Moreover, the whole‐day, morning, and evening systolic blood pressure variability gradually and significantly decreased by the end of the study (5.6 ± 2.1% versus 4.0 ± 1.7%, P<0.001; 7.7 ± 3.5% vs. 6.3 ± 2.7%, P = 0.005; 7.5 ± 2.8% vs. 5.9 ± 2.3%, P = 0.002, respectively). Diastolic blood pressure variability parameters were unchanged. The interdialytic weight gain and the incidence of adverse events were similar throughout the study period. Gradual dry weight reduction by bioimpedance methods improved home blood pressure variability in hemodialysis patients with chronic fluid overload.
Observing Alcohol Myopia in the Context of a Trauma Film Paradigm: Differential Recall of Central and Peripheral Details
Authors: Jaffe Anna E. , Harris Christina M. , DiLillo David 
Published: August 2019

BackgroundA major tenet of the alcohol myopia model is that intoxication results in a narrowing of attention to the most central environmental cues, at the cost of more peripheral information. Though long hypothesized, no known study of alcohol myopia has demonstrated differential immediate recall of central and peripheral cues using a standardized task. To address this gap, we conducted an alcohol administration study with a clear, standardized focus—a trauma film.MethodsNinety‐eight female social drinkers completed self‐report measures, and then were randomized to consume a placebo beverage, a low dose of alcohol (mean breath alcohol concentration [BrAC] = 0.04%), or a high dose of alcohol (mean BrAC = 0.11%). Participants then moved to a staged room where they viewed a film clip depicting a sexual assault. After leaving the room, participants completed a written free recall task of the film and the room.ResultsThe distinction between recall of central and peripheral details was supported by confirmatory factor analysis. Consistent with the alcohol myopia model, relative to placebo, a high dose of alcohol led to impaired recall of peripheral (but not central) details. Although the interaction between BrAC and information type (central vs. peripheral) was not statistically significant, simple effects revealed a strong association between BrAC and peripheral information, and no association between BrAC and central information. Bolstering myopia as an explanation for our findings, neither central nor peripheral information correlated with self‐reported tendencies to dissociate or distract oneself, or typical alcohol consumption or expectancies.ConclusionsAlcohol myopia can be observed through an immediate free recall task following a stressful film. Additional research is needed to continue evaluating dose‐dependent differential recall in larger samples. This task may be useful for clarifying the role of alcohol myopia in clinical phenomena, such as aggressive behavior and processing traumatic events.
Anatomical study of the ventral rami of thoracic spinal nerves in Sapajus apella (Primates: Cebidae)
Authors: de Oliveira Silva Daniela Cristina , Santos Lázaro Antônio , Rosa Alan Bartasson Ferreira , Menezes Reis Lorena Tannus , Carvalho‐Barros Roseâmely Angélica , Silva Zenon , Bernardino‐Júnior Roberto , Carneiro‐Silva Frederico Ozanam 
Published: August 2019

AbstractThis study aimed to describe the gross anatomy of the ventral rami of the thoracic spinal nerves in capuchin monkey (Sapajus apella) and compare with humans and other primate species. Eight specimens, prepared in 10% formalin solution and dissected following routine standard techniques, were used. The animals presented 13–14 pairs of thoracic spinal nerves emerging from the intervertebral foramen and divided into dorsal and ventral rami. The ventral rami of the first 12 or 13 pairs represented intercostal nerves and the latter referred to the subcostal nerve. The intercostal and subcostal nerves gave off muscular and cutaneous branches (lateral and ventral), which promote innervation of muscles and skin associated with the chest and abdominal wall. Atypical anatomy was verified for the 1st, 2nd and 7th to 13th intercostal nerves as well as for the subcostal nerve. The morphological characteristics were similar to those observed in humans and some non‐human primates, especially in the absence of collateral branches.
Vitamin D status is not associated with reproductive parameters in young Spanish men
Authors: Rudnicka A. , Adoamnei E. , Noguera‐Velasco J. A. , Vioque J. , Cañizares‐Hernández F. , Mendiola J. , Jørgensen N. , Chavarro J. E. , Swan S. H. , Torres‐Cantero A. M. 
Published: August 2019

AbstractBackgroundRelatively low sperm count was reported among young Spanish men in 2013. Several potential culprits have been suggested as explanations for reported trends in sperm counts in Western men, including lifestyles. Although controversial, some studies suggest that semen parameters, such as low sperm motility or abnormal morphology, may be associated with low serum vitamin D levels.ObjectivesTo evaluate associations between semen parameters and reproductive hormones and serum 25‐hydroxyvitamin D (25OHD) status in young Spanish men and to examine these associations in relation to dietary intake of vitamin D.Materials and methodsThis cross‐sectional study includes 198 university students recruited in 2010–2011 in southern Spain, who provided samples of blood and semen and food frequencies. Semen quality was evaluated by measuring volume, concentration, sperm counts, motility, and morphology, according to the WHO guidelines. Serum samples were analyzed for total 25OHD and reproductive hormones, including FSH, LH, testosterone, inhibin B, and estradiol. Dietary vitamin D intake was assessed using a validated food frequency questionnaire. Associations with semen quality and reproductive hormones were examined using linear regression, adjusting for potential confounders.ResultsAlmost all men had adequate levels of serum vitamin D ‐ only three men (1.5%) were vitamin D deficient (<30 nmol/L) and 17% were insufficient (<50 nmol/L). However, dietary vitamin D intakes were relatively low (below recommended 600 IU/day in 99% of men). Neither dietary intake nor serum vitamin D levels were associated with any sperm parameter or any reproductive hormone (all p ≥ 0.09).DiscussionWe did not observe an association between vitamin D status and any reproductive parameter in our study population.ConclusionsOur results suggest that serum vitamin D levels are sustained in Spanish men despite low dietary intake and therefore low vitamin D does not explain the poor semen quality previously observed in these young Spanish men.
Distant organ dysfunction in acute kidney injury
Authors: Husain‐Syed Faeq , Rosner Mitchell H. , Ronco Claudio 
Published: August 2019

AbstractAcute kidney injury (AKI) is a common complication in critically ill patients and it is associated with increased morbidity and mortality. Epidemiological and clinical data show that AKI is linked to a wide range of distant organ injuries, with the lungs, heart, liver, and intestines representing the most clinically relevant affected organs. This distant organ injury during AKI predisposes patients to progression to multiple organ dysfunction syndrome and ultimately, death. The strongest direct evidence of distant organ injury occurring in AKI has been obtained from animal models. The identified mechanisms include systemic inflammatory changes, oxidative stress, increases in leucocyte trafficking and the activation of proapoptotic pathways. Understanding the pathways driving AKI‐induced distal organ injury are critical for the development and refinement of therapies for the prevention and attenuation of AKI‐related morbidity and mortality. The purpose of this review is to summarize both clinical and preclinical studies of AKI and its role in distant organ injury.
Assessment of Extracorporeal Treatments in Poisoning criteria for the decision of extracorporeal toxin removal in lithium poisoning
Authors: Vodovar Dominique , Beaune Sébastien , Langrand Jérôme , Vicaut Eric , Labat Laurence , Mégarbane Bruno 
Published: August 2019

AimsTo assess recommendations provided by the EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup on extracorporeal toxin removal (ECTR) in lithium poisoning.MethodsRetrospective assessment in a 128 lithium‐poisoned patient cohort previously used to identify ECTR initiation criteria that could improve outcome (Paris criteria). ECTR requirement using EXTRIP criteria was compared to the actual practice or if Paris criteria were used. The potential impact on outcome if these different criteria were used was investigated.ResultsUsing the recommended (Rec‐EXTRIP) or recommended + suggested (All‐EXTRIP) EXTRIP criteria, ECTR would have been indicated in more patients than was actually done (P < .001), or if Paris criteria were used (P < .01). The non‐actually ECTR‐treated patients fulfilling Rec‐EXTRIP or All‐EXTRIP criteria had shorter intensive care unit stay (P < .05) and no significant increase in fatalities and neurological impairment on discharge in comparison to the actually ECTR‐treated patients. ECTR requirements using EXTRIP vs Paris criteria were not concordant (P < .001). In the non‐actually ECTR‐treated patients, 31/106 and 55/106 patients fulfilled Rec‐EXTRIP or All‐EXTRIP but not Paris criteria, respectively. Those patients had longer stay (P < .01) but no worse neurological impairment on discharge than the patients not fulfilling any of these criteria (50/106 and 26/106, respectively). In the non‐actually ECTR‐treated patients, 7/106 fulfilled Paris but not Rec‐EXTRIP criteria. Those patients had longer stay (P < .05) and worse neurological impairment on discharge (P < .01) than the 50/106 patients not fulfilling any of these criteria.ConclusionIn this cohort of lithium poisonings, EXTRIP criteria may lead to more ECTR than actually performed or if the Paris criteria were used, with no demonstrated improvement in outcome.
Health‐related quality of life among non‐muscle‐invasive bladder cancer survivors: a population‐based study
Authors: Jung Ahrang , Nielsen Matthew E. , Crandell Jamie L. , Palmer Mary H. , Smith Sophia K. , Bryant Ashley Leak , Mayer Deborah K. 
Published: August 2019

ObjectiveTo examine the effect of non‐muscle‐invasive bladder cancer (NMIBC) diagnosis and treatment on survivors’ quality of life (QoL).Patients and MethodsOf the 5979 patients with NMIBC diagnosed between 2010 and 2014 in North Carolina, 2000 patients were randomly selected to be invited to enroll in this cross‐sectional study. Data were collected by postal mail survey. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire‐Core (QLQ‐C30) and the NMIBC‐specific module were included in the survey to measure QoL. Descriptive statistics,t‐tests,anova, and Pearson's correlation were used to describe demographics and to assess how QoL varied by sex, cancer stage, time since diagnosis, and treatment.ResultsA total of 398 survivors returned questionnaires (response rate: 23.6%). The mean QoL score for QLQ‐C30 (range 0–100, higher = better QoL in all domains but symptoms) for global health status was 73.6, function domain scores ranged from 83.9 to 86.5, and scores for the top five symptoms (insomnia, fatigue, dyspnoea, pain, and financial difficulties) ranged from 14.1 to 24.3. The lowest NMIBC‐specific QoL domain was sexual issues including sexual function, enjoyment, problems, and intimacy. Women had worse bowel problems, sexual function, and sexual enjoyment than men but better sexual intimacy and fewer concerns about contaminating their partner. Stage Ta had the highest global health status, followed by T1 and Tis. QoL did not vary by time since diagnosis except for sexual function. The cystectomy group (n= 21) had worse QoL in sexual function, discomfort with sexual intimacy, sexual enjoyment, and male sexual problems than the non‐cystectomy group (n= 336).ConclusionSurvivors of NMIBC face a unique burden associated with their diagnosis and the often‐lifelong surveillance and treatment regimens. The finding has important implications for the design of tailored supportive care interventions to improve QoL for NMIBC survivors.
A novel PTPRZ1‐ETV1 fusion in gliomas
Authors: Matjašič Alenka , Zupan Andrej , Boštjančič Emanuela , Pižem Jože , Popović Mara , Kolenc Danijela 
Published: August 2019

AbstractThe aggressive nature of malignant gliomas and their genetic and clinical heterogeneity present a major challenge in their diagnosis and treatment. Development of targeted therapy brought attention on detecting novel gene fusions, since they represent promising therapeutic targets (eg, TRK inhibitors in NTRK fusion‐positive tumors). Using targeted next‐generation sequencing, we prospectively analyzed 205 primary brain tumors and detected a novel PTPRZ1‐ETV1 fusion transcript in 11 of 191 (5.8%) gliomas, including nine glioblastomas, one anaplastic oligodendroglioma and one pilocytic astrocytoma. PTPRZ1‐ETV1 fusion was confirmed by RT‐PCR followed by Sanger sequencing, and in‐silico analysis predicted a potential driver role. The newly detected fusion consists of the PTPRZ1 promoter in frame with the highly conserved DNA‐binding domain of ETV1 transcription factor. The ETV1 and PTPRZ1 genes are known oncogenes, involved in processes of tumor development. ETV1 is a member of the ETS family of transcription factors, already known oncogenic drivers in Ewing sarcoma, prostate cancer and gastrointestinal stromal tumors, but not in gliomas. Its overexpression contributes to tumor growth and more aggressive tumor behavior. PTPRZ1 is already considered to be a tumor growth promoting oncogene in gliomas. In 8%–16% of gliomas, PTPRZ1 is fused to the MET oncogene, resulting in a PTPRZ1‐MET fusion, which is associated with poorer prognosis but is also a positive predictive biomarker for treatment with kinase inhibitors. In view of the oncogenic role that the two fusion partners, PTPRZ1 and ETV1, exhibit in other malignancies, PTPRZ1‐ETV1 fusion might present a novel potential therapeutic target in gliomas. Although histopathological examination of PTPRZ1‐ETV1 fusion‐positive gliomas did not reveal any specific or unique pathological features, and the follow‐up period was too short to assess prognostic value of the fusion, careful monitoring of patients and their response to therapy might provide additional insights into the prognostic and predictive value of this novel fusion.
Genome‐wide interaction study of early‐life smoking exposure on time‐to‐asthma onset in childhood
Authors: Sugier Pierre‐Emmanuel , Sarnowski Chloé , Granell Raquel , Laprise Catherine , Ege Markus J. , Margaritte‐Jeannin Patricia , Dizier Marie‐Hélène , Minelli Cosetta , Moffatt Miriam F. , Lathrop Mark , Cookson William O. C. M. , Henderson A. John , von Mutius Erika , Kogevinas Manolis , Demenais Florence , Bouzigon Emmanuelle 
Published: August 2019

AbstractBackgroundAsthma, a heterogeneous disease with variable age of onset, results from the interplay between genetic and environmental factors. Early‐life tobacco smoke (ELTS) exposure is a major asthma risk factor. Only a few genetic loci have been reported to interact with ELTS exposure in asthma.ObjectiveOur aim was to identify new loci interacting with ELTS exposure on time‐to‐asthma onset (TAO) in childhood.MethodsWe conducted genome‐wide interaction analyses of ELTS exposure on time‐to‐asthma onset in childhood in five European‐ancestry studies (totalling 8273 subjects) using Cox proportional‐hazard model. The results of all five genome‐wide analyses were meta‐analysed.ResultsThe 13q21 locus showed genome‐wide significant interaction with ELTS exposure (P = 4.3 × 10−8 for rs7334050 within KLHL1 with consistent results across the five studies). Suggestive interactions (P < 5 × 10−6) were found at three other loci: 20p12 (rs13037508 within MACROD2; P = 4.9 × 10−7), 14q22 (rs7493885 near NIN; P = 2.9 × 10−6) and 2p22 (rs232542 near CYP1B1; P = 4.1 × 10−6). Functional annotations and the literature showed that the lead SNPs at these four loci influence DNA methylation in the blood and are located nearby CpG sites reported to be associated with exposure to tobacco smoke components, which strongly support our findings.Conclusions and Clinical RelevanceWe identified novel candidate genes interacting with ELTS exposure on time‐to‐asthma onset in childhood. These genes have plausible biological relevance related to tobacco smoke exposure. Further epigenetic and functional studies are needed to confirm these findings and to shed light on the underlying mechanisms.
Physical and mental health changes in aging foster parents: Do child behavioural problems hasten declines?
Authors: Helton Jesse J. , Khoo Yit Mui , Wallace Cara L. , Whitehead Ashley , Kebbe Caroline 
Published: August 2019

AbstractThis study examined foster parent physical and mental health over time. It was hypothesized that increased severity and frequency of child behavioural problems, whether externalizing or internalizing, would be associated with poorer health over time, especially for foster parents ≥60 years of age. Data from the baseline and Wave 2 interview of the 2010 National Survey of Child and Adolescent Well‐Being were used. The final analytic sample included kin and nonkin foster parents who had custody of a foster child for both waves of data collection (n = 962). Ordinary Least Squares regression models with lagged dependent variables showed that foster parents ≥60 had deteriorating physical health over time, but caregiver age alone had no association with worsening mental health. However, parents ≥60 caring for children with externalizing behavioural problems had significantly improved physical health. Mental health of parents ≥60 significantly diminished if child externalizing or internalizing problems worsened. Findings indicate that for aging foster parents, externalizing child behaviours may stimulate physical activity and improved physical health, yet any type of child behavioural problem can deteriorate mental health functioning.