bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanical properties and microscopic damage characteristics of coal-series limestone under real-time coupling effects of high temperature and impact
Authors: wu peng , zhang lianying , li bing , zheng yadong , li ming , zhu fuqiang 
Published: November 2024

Abstract

To ensure the safe extraction of deep mineral resources, it is imperative to address the mechanical properties and damage mechanism of coal and rock media under the real-time coupling effect of high temperature and impact. In this study, the impact tests (impact velocities of 6.0-10.0 m/s) on coal-series limestone under real-time high-temperature conditions (25 ℃-800 ℃) were conducted by the real-time high-temperature split Hopkinson pressure bar (HT-SHPB) testing system, and the microscopic changes in mineral composition under the coupling effect of real-time high-temperature and high strain rate action were investigated by X-ray diffraction (XRD), electron scanning microscopy (SEM), energy dispersive spectroscopy (EDS). The results showed that the dynamic stress-strain curve of coal-series limestone under the real-time coupling effect of high temperature and impact during the compaction stage was not significant; As the impact velocity increases and the temperature increases, the plastic characteristics of the dynamic stress-strain curve become more notable, and the brittle failure of the sample is gradually changed into brittle-ductile failure. Additionally, the dynamic peak stress and dynamic elastic modulus exhibit distinct quadratic variations with the increased temperature, and the dynamic peak stress approximately increases linearly with the impact velocity. The main substances in coal-series limestone are calcite, dolomite, and muscovite. The microscopic morphology of calcite at room temperature is characterized by a thin stepped or layered structure. When the temperature rises to 800 ℃, thermal decomposition rarely occurs in calcite, while its physical and mechanical properties undergo alternations. After real-time impact, the degree of crystal fragmentation of calcite increases and a large number of microcracks are generated. The dolomite exhibits a prismatic microscopic morphology at room temperature, characterized by distinct and flat edges, and typically occurs in clusters. When the temperature rises to 600 ℃, an increased amount of dolomite initiates thermal decomposition, and the crystal edges become passive, even leading to the granulation phenomenon. Consequently, the impact mechanical properties of limestone are ultimately weakened due to the thermal decomposition of mineral components and changes in physical and mechanical properties caused by high temperature.
Injection angles on flow structures and mixing properties in a supersonic combustor at low Mach crossflow
Authors: Zhang Lin , Liang Jianhan , Wang Yi , Zhao Wei , Yang Leichao 
Published: November 2024

Abstract

The fuel-air mixing is of paramount importance in hypersonic air-breathing vehicles, and its performance is closely related to the fuel injection angle. This article presents an investigation into the influence of the injection angles on the flow and mixing processes in a supersonic combustor at low Mach supersonic inflow. Detailed flow characteristics are compared and analyzed, with a focus on instantaneous and average flows. Besides, several significant mixing parameters are thoroughly depicted. Results show that, in contrast to transverse injection, relatively strong fuel fluctuation is presented on the leeward side in comparison to the windward side in the near field for the inclined injection. Furthermore, the counter-rotating vortex pairs (CVP) are constricted by the inclination of the injection, giving rise to a decrease in jet-cavity interaction. Although inclined injection exhibits favorable performance in backpressure resistance at low Mach supersonic crossflow, it presents a greater challenge in terms of ignition, thus necessitating meticulous design considerations.
The impact of family physical education and physical activity on adolescents' social emotional competence: the moderating role of positive youth development
Authors: Zhang Lanxing , Bi XIN 
Published: November 2024

Abstract

Family function theory attests that the role of family in shaping the social emotional competence of adolescents is truly irreplaceable. This study, adopting family function theory and social ecology theory as the analytical framework, delves into the potential mechanism by which family physical education impacts the social and emotional abilities of adolescents. Accordingly, 1,062 students from 19 middle schools in China were selected to examine the role of physical activity and positive adolescent development in the relationship between family physical education and adolescent social emotions. The results indicate that: (1) Family physical education positively predicts the social emotional competence of adolescents. (2) Physical activity serves as an intermediary in the relationship between family physical education and adolescent social emotion competence. (3) positive youth development plays a regulatory role in the relationship between family physical education and the social and emotional competence of adolescents. Thus, parents should be cognizant of the significance of family physical education in cultivating the social and emotional abilities of adolescents. At the same time, families ought to attach importance to the positive development of adolescents, provide them with sufficient support, engage in more physical activities with their children, increase adolescents' participation in physical activities, and ultimately contribute to the improvement of adolescents' social and emotional competence.
Future-Proofing China's Rivers: Balancing Nitrogen Emission Standards Amidst Climate Change
Authors: Wei Chaohai , Guan Hong , Li Zemin , Ru Xuan , Chen Acong , Xie Mengyi , Qiu Guanglei , Hu Yun 
Published: November 2024

Abstract

Despite China taking significant steps to reduce nitrogen input from human activities into inland rivers by raising nitrogen emission standards, climate change has exacerbated the flow of reactive nitrogen, creating additional pressure for nitrogen reduction. To evaluate the necessity and sustainability of these raised standards, this study presents a comprehensive data set summarizing total nitrogen and ammonia concentrations from 1702 sites across 10 major basins from 2015 to 2024. The analysis normalizes factors, including land use, nitrogen deposition, litter, soil leaching, biological nitrogen fixation, and the spatiotemporal fluxes of agricultural fertilization, organized by month within 50 × 50 km grids. Using numerical training, the study assesses the influence of these factors on river nitrogen exposure and predicts changes in river nitrogen levels under four climate change scenarios and three emission scenarios for 2050. The findings indicate that if climate change continues at the current rate (ssp3–7.0), total nitrogen concentrations in rivers nationwide could increase by (6.51 ± 13.68) %. However, raising the total nitrogen concentration standard from 20 mg L⁻1 to 15 mg L⁻1 can reduce the total nitrogen concentration in rivers by (8.22 ± 19.39) %. Nitrogen emission policies should be tailored to specific river basins and seasons. Notably, northern river basins may need to elevate nitrogen emission standards to Class IV to counterbalance the additional nitrogen emissions resulting from climate change.
Health Risks Evaluation of Mycotoxins in Plant-Based Supplements Marketed in Malaysia
Authors: Abdullah Rozaini , Kamarozaman Nur Syazwin , Dullah Siti Soleha Ab , Aziz Mohd Yusmaidie , Adam Aziza Hussein Bakheit 
Published: November 2024

Abstract

Mycotoxins are toxic secondary metabolites produced by fungi, pose significant health risks when present in plant-based supplements (PBS), necessitating thorough risk assessment to ensure consumer safety. This study evaluates the health risks associated with mycotoxins, specifically aflatoxins (AFB1, AFB2) and ochratoxin A (OTA), in PBS sold in Malaysia. Contamination levels of AFB1, AFB2, and OTA were quantified in 14 PBS samples using liquid chromatography-mass spectrometry. All samples tested positive for AFB2, while 28.57% and 42.86% tested positive for AFB1 and OTA, respectively with some levels exceeding the regulatory limits set by the Malaysian Food Act 1983. The estimated daily intake of these mycotoxins was calculated based on the recommended daily intake of each supplement. To assess risk, Margin of Exposure (MOE) values were determined, showing that all AFB2-positive samples had MOE values below the critical threshold of 10 000, indicating an urgent need for risk management. A quantitative cancer risk assessment also estimated the percentage of hepatocellular carcinoma and kidney cancer attributable to mycotoxin exposure. The findings emphasize the significant public health risks posed by mycotoxins, particularly in samples B2 and B10, where all three mycotoxins studied were present at concerning levels. This study highlights the urgent need for stricter regulations and better monitoring of mycotoxin levels in PBS to protect consumers.
Research on the Meso-mechanism of the Evolution of Wet - swelling Cracks in Expansive Soil based on Discrete Element Method
Authors: Ran HAI , Shuoshuo GUO , CHENG Xuelei , LI Qiqi , Xiaofan Xing 
Published: November 2024

Abstract

In order to study the crack evolution law of expansive soil caused by wet - swelling under rainfall conditions, the water migration model corresponding to the heat conduction equation is derived based on the heat conduction theory. Based on PFC, a discrete element numerical model of wet - swelling deformation of expansive soil under the coupling action of humidity and stress is established. The Meso-mechanism of the evolution of wet - swelling cracks is revealed, and the influence law of model parameters on crack development is analyzed. The research found that rainfall infiltration leads to slight wet - swelling deformation of the shallow surface. As rainfall continues further, the surface wet expansion deformation significantly expands to the deep soil layer. However, the depth of soil layer affected gradually stabilizes, and slight uplift and cracks appear in the shallow soil layer. Eventually, multiple through cracks are formed in the foundation and the ground surface significantly uplifts. At the same time, the adjustment of model parameters such as permeability coefficient, tensile strength, elastic modulus and expansion coefficient has a significant impact on cracks development. The research results can not only be used to avoid the problem of expansive soil characteristics, based on the influence of model parameters on the development of cracks, suggestions for foundation improvement of weak expansive soil are put forward, the modification and improvement of engineering foundation provides an important theoretical reference.
Serendipita indica Enhances Growth, Photosynthesis, and Secondary Metabolite Profiles in Acorus calamus
Authors: He Qiang , Yang Yujie , Wu Chu , Liu Jianxiong , Li Hao , Luo Yuexing 
Published: November 2024

Abstract

Aims
Acorus calamus is widely recognized for its therapeutic potential in treating neurological, cardiovascular, and gastrointestinal disorders. Serendipita indica has been shown to promote growth and enhance secondary metabolite production in several plants; however, it is unknown whether S. indica remain beneficial effects on A. calamus.
Methods
A. calamus was cultured in soil with or without S. indica to assess changes in photosynthesis, biomass, and secondary metabolites. The cultivars were grown in a growth chamber in a completely randomized design with two treatment groups: inoculated and non-inoculated, each with three replications. Successful colonization was confirmed microscopically, distinguishing between control (CK) and experimental (P+) groups.
Results
The roots of A. calamus can be colonized by S. indica. Results showed an increase in stem length, creeping stem branches, and root surface area post-colonization after inoculation with S. indica. Meanwhile, the colonization of S. indica in A. calamus roots led to improve photosynthetic efficiency, reflected by increased photosynthetic rate, intercellular CO2 concentration, stomatal conductance, and transpiration rate. Furthermore, among the 170 compounds identified in A. calamus, 25 showed increased levels post-inoculation, including lipids, acids, sugars, amino acids and their derivatives, saponins, phenols, alcohols, flavonoids, aldehydes, sterols, heterocyclic compounds, fatty acid ethanolamides, hydrocarbons, alkaloids, phenylpropanoids, and ketones.
Conclusion
These results underscore the potential of S. indica in enhancing the medicinal properties of A. calamus, suggesting a promising avenue for its agricultural and pharmacological applications.
Chiang Mai VGOS 13m Radio Telescope Remote Health Monitoring System
Authors: Shang-Guan Wei-Hua , Zhao Rong-Bing , Wang Jin-Qing , Li Jin-Ling , Guo Shao-Guang , Jiang Yong-Bin , Yan Zhen , Ba-Shang Fan-Duo , Dai Heng 
Published: November 2024

Abstract

The VGOS 13m radio telescope located in Chiang Mai, Thailand is the first VGOS standard station built overseas by China. This station expands Chinese very long baseline interferometry (VLBI) network (CVN) and furthers multiple scientific goals, such as continuous monitoring of Earth orientation parameters and research into the terrestrial and celestial reference frames. The station is equipped with wideband 2-14GHz receivers and X/Ka dual-frequency receivers, a high-speed antenna, a DBBC3 high-speed data acquisition terminal and a high-speed recording terminal. This is aimed at improving observation efficiency and research quality. We developed the Remote Health Monitoring System (RHMS) specifically for the VGOS 13m radio telescope located in Thailand. This system integrates Tango Controls' distributed middleware technology, allowing it to furnish the observation team with comprehensive historical and real-time status updates for the Chiang Mai VGOS station. Additionally, it promptly issues alerts for abnormalities, thereby improving the station's unmanned monitoring, maintenance and operations capabilities, and operational performance. It also provides a feasible solution for remote monitoring of future overseas VGOS stations.
Comparing the Efficacy and Safety of Remimazolam versus Propofol in Gastrointestinal Endoscopy or Fiberoptic Bronchoscopy: A systematic review and meta-analysis of Randomized Controlled Trials
Authors: Zhang Jie , Ye Ling , Xiang Bangyi , Feng Xixia , Zhou Ruihao 
Published: November 2024

Abstract

Background
While propofol is generally utilized for sedation in endoscopic procedures, its safety has been questioned. Remimazolam, a newer alternative, promises better safety but lacks extensive comparative data. This meta-analysis aims to assess the efficacy and safety of remimazolam in comparison with propofol when used in gastrointestinal endoscopy or fiberoptic bronchoscopy.
Methods
A comprehensive literature search was carried out across PubMed, the Cochrane Central Register of Controlled Trials, Embase, Web of Science, Wanfang, and VIP databases up until October 2023. This search aimed to identify randomized controlled trials (RCTs) that compared remimazolam with propofol regarding to their efficacy and safety in the context of gastrointestinal endoscopy or fiberoptic bronchoscopy. Sedation success rate was the primary outcome while secondary outcomes encompassing additional efficacy measuresand safety parameters
Results
Fifteen RCTs were involved in this study. When compared with propofol, remimazolam displayed a lower success rate of sedation (P < 0.001; I2 = 58%), but featured a reduced induction time (P = 0.0004; I2 = 96%), a quicker return to full alertness (P = 0.001; I2 = 89%), and fewer adverse events (P < 0.001; I2 = 77%). No significant disparities were observed in operation duration, recovery time (P = 0.52; I2 = 92%), or discharge time (P = 0.52; I2 = 86%).
Conclusion
Despite a lower sedation success rate compared to propofol, remimazolam offers significant advantages, including a shorter induction time, a quicker recovery to full alertness, and fewer adverse events. These attributes make remimazolam a compelling alternative for sedation in endoscopic procedures.
Genome wide identification of Plant based natural Antimicrobial Peptides using deep learning approach in Black pepper
Authors: Negi Ankita , Singh Kalpana , Ahmed Bulbul , Jaiswal Sarika , Iquebal Mir Asif , Angadi U. B. , Rai Anil , Kumar Dinesh 
Published: November 2024

Abstract

Background
Black pepper (Piper nigrum, 2n = 52) has been traditionally used for the treatment of various diseases owing to its therapeutic properties, namely, antimicrobial, anti-inflammatory, antioxidant and anti-cancerous properties since time immemorial. Antimicrobial peptides (AMPs) aka ‘nature's antibiotics’ or ‘host defense peptides’ produced by most living organisms as an innate immune response against microbes and have gained popularity due to rising multidrug resistance of microorganisms, new microbial infections, and a great dearth of novel antibiotics in recent years. A Numerous studies are reported on AMPs’ defense mechanism and its different modes of action in animals, showing its immunomodulatory properties and potentiality in combating against multi-drug resistant microbes. But in plants, especially spice crops, like black pepper, that has huge therapeutic properties and potential to improve immunity to combat against microbial infections needed to be further explored.
Result
This study provides a species-specific AMP candidate prediction server BPepAMPred (http://login1.cabgrid.res.in:5040/) based on 10 fold cross validated bidirectional- gated recurrent unit based deep neural network architecture with 99.34% accuracy, 98.68% sensitivity, 98.67% specificity. This server also linked with BPepAMPdb (http://backlin.cabgrid.res.in/blackpepper_amp_db/) which catalogs predicted 43759 AMP candidates across black pepper proteome along with 10935 functionally associated unique genes, chromosome number, genomic location, associated gene ids and functional properties.
Conclusion
The exhaustive molecular information of black pepper crop at one place in the user-friendly way to access would be beneficial for the breeders for black pepper improvement program. It could be utilized by molecular biologists for wet-lab preparation and validation of AMPs which could further be used in the development of novel therapeutic molecule and help to enhance the microbial resistance in black pepper and other crops.
GW8510 alleviated muscle atrophy and skeletal muscle dysfunction in mice through AMPK/PGC1α signaling
Authors: Chen Yutong , Liu Zurui , Liu Chen , Yang Daqian , Xie Zhengwei 
Published: November 2024

Abstract

Background
To prevent and restore muscle loss and function is important for elderly people. Here, we explore the protective effect of GW8510 on muscle atrophy.
Methods
The denervation, dexamethasone, and glycerol-induced muscle atrophy mice were constructed and the ratio of muscle weight to body weight, the cross-sectional area of multiple muscles, grip strength, fatigue task, and serum analysis were assessed. In Vitro experiment, we constructed dexamethasone-induced C2C12 myotube atrophy and evaluated the mitochondrial function. Moreover, we applied real-time polymerase chain reaction, immunoblotting, and transfection with siRNA to investigate the potential molecular mechanism after GW8510 treatment.
Results
GW8510 significantly increases the ratio of gastrocnemius tissue and soleus in denervation mice (6.8% and 3.1%, respectively, P < 0.001), and increased cross-sectional area. Meanwhile, GW8510 significantly improved grip strength and SOD activity (P < 0.0001), and these protective effects were also found similarly in dexamethasone and glycerol-induced muscle atrophy mice. Furthermore, GW8510 reduced reactive oxygen species production (P < 0.01), increased mitochondrial DNA copy number (P < 0.01), maintained mitochondrial dynamics, and enhanced the antioxidation in C2C12 myotubes. Mechanistically, GW8510 significantly inhibited the expression of atrophy-related markers, Fbxo32 and Trim63 (P < 0.01 and activated AMPK (P < 0.01). Knockdown of small interfering RNA abolished the effect of GW8510 and knockdown of Src synergistically reduced atrophy-related protein.
Conclusion
GW8510 alleviated muscle atrophy through activation of AMPK/ PGC1α. Our study identified that GW8510 can be a novel therapeutical agent for preventing muscle atrophy, and Src may be a novel therapeutical target.
Environmental Impact Prediction
Authors: Vivaan Vivaan Kaundinya , Abhi Abhijeet Kant Kumar 
Published: November 2024

Abstract

Predicting environmental impacts is crucial for evaluating and reducing how human activity affects ecosystems, particularly when it comes to pollution, resource depletion, and climate change. In order to predict changes in the environment, this study looks at a variety of predictive models, including both sophisticated machine learning techniques and conventional statistical methods. We provide an integrated framework that increases prediction accuracy by utilizing data from several sources, including satellite images, climate records, air and water quality indexes, and socioeconomic characteristics. Using machine learning models, the study shows improved performance in short-term predictions of water pollution, soil deterioration, and air quality. However, due to data limitations and the complexity of ecological systems, long-term, complicated predictions—like those regarding habitat degradation and biodiversity loss—remain difficult. According to our research, enhancing future environmental effect projections and facilitating more sustainable decision-making processes would need incorporating real-time data, growing datasets, and creating adaptive models.
Using LLMs as AI Agents to Identify False Positive Alerts in Security Operation Center
Authors: Rafiey Pasha , Namadchian Amin 
Published: November 2024

Abstract

This paper addresses the challenges and solutions related to identifying false positive (FP) alerts in Security Information and Event Management (SIEM) systems, which often overwhelm security operators. To tackle this issue, we propose a novel approach that employs a Large Language Model (LLM), specifically Llama, as an AI agent through a contextual-based approach to identify FPs in security alerts generated by multiple network sensors and collected in Security Operations Centers (SOCs). Our method follows three key steps: data extraction, enrichment, and playbook execution. First, Llama normalizes security alerts using a common schema, extracting key contextual elements such as IP addresses, host names, filenames, services, and vulnerabilities. Second, these extracted elements are enriched by integrating external resources such as threat intelligence databases and Configuration Management Databases (CMDB) to generate dynamic metadata. Finally, this enriched data is analyzed through predefined false positive investigation playbooks, designed by security professionals, to systematically evaluate and identify FPs.By automating the false positive identification process, this approach reduces the operational burden on human security operators, enhancing the overall efficiency and accuracy of SOCs, and improving the organization's security posture.