bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiac implantable electronic devices in adults with tetralogy of Fallot
Authors: Egbe Alexander C , Miranda William R , Madhavan Malini , Ammash Naser M , Missula Venkata R , Al-Otaibi Mohammed , Fatola Ayotola , Kothapalli Srikanth , Connolly Heidi M 
Published: October 2018

BackgroundTachyarrhythmias and bradyarrhythmias affect 20%–50% of adult patients with tetralogy of Fallot (TOF) and some of these patients will require cardiac implantable electronic devices (CIED) such as pacemaker and/or internal cardioverter defibrillator.MethodsThe Mayo Adult Congenital Heart Disease database was queried for patients with repaired TOF and history of CIED implantation, 1990–2017. The study objectives were: (1) determine the occurrence of device-related complications defined as lead failure, lead recall, device infection and lead thrombus; and (2) determine the occurrence and risk factors for defibrillator shock.ResultsThere were 99 patients (age 46±14 years and 66 (66%) men) with CIED, and the CIEDs were 41 (41%) pacemakers and 73 (73%) defibrillators. Indication for defibrillator implantation was for primary prevention in 28 (38%) and secondary prevention in 45 (62%). Device-related complications occurred in 20 (20%) patients (lead failure 17, lead recall 4, device infection 12 and thrombus 3). Twenty-five per cent of all device infections occurred within 30 days from the time of device generator change. Annualised rates of appropriate and inappropriate shocks were 5.7% and 6.2%, respectively. The use of class III antiarrhythmic drug was protective against defibrillator shock.ConclusionThe current study provides useful outcome data to aid patient counselling and clinical decision-making. Further studies are required to explore ways to decrease the risk of postprocedural infection after device generator change, and to determine which patients will benefit from empirical antiarrhythmic therapy as a strategy to decrease incidence of inappropriate defibrillator shock.
A Higgs boson below 125 GeV?!
Authors: Heinemeyer S. 
Published: October 2018

We briefly summarize some searches for Higgs bosons with a mass of [Formula: see text] GeV at LEP and the LHC. We discuss a possible signal in the diphoton decay mode at [Formula: see text] GeV as reported by CMS, together with a [Formula: see text] hint in the [Formula: see text] final state at LEP. We briefly review possible interpretation of such a new particle in various BSM models. We focus on possible explanations as reported within the NMSSM and the [Formula: see text]SSM. Conclusions for future collider projects are briefly outlined.
Os conceitos kantianos e a música
Authors: Justi Vicente de Paulo 
Published: October 2018

No presente artigo discutimos os conceitos kantianos apresentados na Terceira Crítica como sensação, sentimento, comoção, afeto, prazer, forma, conformidade a fins, intuição, juízos e reflexão. O objetivo principal é verificar se estes conceitos, tal como apresentados por Kant, podem ainda contribuir para a nossa compreensão do fenômeno musical.
A percepção do timbre em Farben Op. 16 n. 3 de Schoenberg: uma abordagem estética e psicoacústica
Authors: Rossetti Danilo 
Published: October 2018

Farben Op. 16 nº3 é uma obra em que Arnold Schoenberg implementa seu modelo de melodia de timbres (Klangfarbenmelodie), modelo este que talvez nunca tenha sido repetido da mesma maneira em suas demais obras. Neste artigo investigamos os processos de composição e percepção do timbre nesta obra. Como referencial teórico abordamos a busca estética do compositor por uma relação entre cores e sons, fundamentada nas ideias Goethe (1840) e Helmholtz (1924, 1954). Baseamo-nos também em teorias sobre a percepção da altura por fusão de parciais e sobre a fusão de diferentes timbres por jitter. Sobre Farbenrealizamos uma análise da partitura baseada principalmente em trabalhos prévios de Förtig (1969) e Burkhart (1972). A seguir partimos para uma investigação psicoacústica da percepção do timbre, para tanto aplicamos ao áudio da obra os descritores croma, centroide, sharpness, loudness e inarmonicidade (através do programa Sonic Visualizer), os quais nos forneceram dados para realizar interpretações individuais destes parâmetros, bem como nos permitindo estabelecer relações entre eles.
Long‐Term Time‐Varying Risk of Readmission After Acute Myocardial Infarction
Authors: Khot Umesh N. , Johnson Michael J. , Wiggins Newton B. , Lowry Ashley M. , Rajeswaran Jeevanantham , Kapadia Samir , Menon Venu , Ellis Stephen G. , Goepfarth Pamela , Blackstone Eugene H. 
Published: October 2018

Background

Readmission after myocardial infarction (
MI
) is a publicly reported quality metric with hospital reimbursement linked to readmission rates. We describe the timing and pattern of readmission by cause within the first year after
MI
in consecutive patients, regardless of revascularization strategy, payer status, or age.

Methods and Results

We identified patients discharged after an
MI
from April 2008 to June 2012. Readmission within 12 months was the primary end point. Readmissions were classified into 4 groups:
MI
related, other cardiovascular, noncardiovascular, and planned. A total of 3069 patients were discharged after an
MI
(average age, 65±13 years; and 1941 [63%] men). A total of 655 patients (21.3%) were readmitted at least once (897 total readmissions). A total of 147 patients (4.8%) were readmitted ≥2 times, accounting for 389 readmissions (43%). The instantaneous risk of all‐cause readmission was highest (15 readmissions/100 patients per month; 95% confidence interval, 12–19 readmissions/100 patients per month) immediately after discharge, decreased by almost half (8.1 readmissions/100 patients per month; 95% confidence interval, 7.2–9.0 readmissions/100 patients per month) within 15 days, and was substantially lower and relatively constant (1.4 readmissions/100 patients per month; 95% confidence interval, 1.2–1.6 readmissions/100 patients per month) out to 1 year. Cardiovascular causes of readmission were more common early after discharge.

Conclusions

Most patients with MI are never readmitted, whereas a small minority (≈5%) account for nearly half of 1‐year readmissions. The readmission pattern after
MI
is characterized by an early peak (first 15 days) of cardiovascular readmissions, followed by a middle period (months 1–4) of noncardiovascular readmissions, and ending with a low‐risk period (>4 months) during which the risk appears independent of cause.
Association Between a 20‐Year Cardiovascular Disease Risk Score Based on Modifiable Lifestyles and Total and Cause‐Specific Mortality Among US Men and Women
Authors: Sotos‐Prieto Mercedes , Mattei Josiemer , Cook Nancy R. , Hu Frank B. , Willett Walter C. , Chiuve Stephanie E. , Rimm Eric B. , Sesso Howard D. 
Published: October 2018

Background
The previously validated Healthy Heart Score effectively predicted the 20‐year risk of cardiovascular disease (CVD). We examine whether the Healthy Heart Score may extend to an association with total and cause‐specific mortality.

Methods and results
The prospective cohort study investigated 58 319 women (mean age 50.2 years) in the Nurses’ Health Study (1984–2010) and 29 854 in men (mean age 52.7 years) in the Health Professionals’ Follow‐up Study (1986–2010) free of cancer and CVD at baseline. The Healthy Heart Score included baseline current smoking; high body mass index; low physical activity; no or excessive alcohol intake; low intake of fruits and vegetables, cereal fiber, or nuts; and high intake of sugar‐sweetened beverages or red/processed meats. There were 19 122 total deaths. Compared with participants in the first quintile of the Healthy Heart Score (lowest CVD risk), participants in the fifth quintile (highest CVD risk) had a pooled hazard ratio of 2.26 (95% confidence interval [CI], 1.53–3.33) for total mortality; 2.85 (95 % CI, 1.92–4.23) for CVD mortality, and 2.14 (95% CI, 1.56–2.95) for cancer mortality. Participants in the fifth versus the first quintile also had significantly greater risk of death due to coronary heart disease (3.37; 95% CI, 2.16–5.25), stroke (1.75; 95% CI, 1.02–2.99), lung cancer (6.04; 95% CI, 2.78–13.13), breast cancer (1.45; 95% CI, 1.14–1.86), and colon cancer (1.51; 95% CI, 1.18–1.93).

Conclusions
The Healthy Heart Score, composed of 9 self‐reported, modifiable lifestyle predictors of CVD, is a potentially useful tool for the counseling of healthy lifestyles that was strongly associated with greater risk of all‐cause, CVD, and cancer mortality.
Studying the Intentionality of Human Being
Authors: Feilberg Casper , Norlyk Annelise , Keller Kurt Dauer 
Published: October 2018

AbstractBased upon a brief outline of existential-phenomenological ontology we present a theoretical and practical understanding of humanbeing, which is suited for a methodologically reflected approach to qualitative research. We present the phenomenological distinction between threedimensions of corporeal intentionality(structural, generative and dialectic intentionality) that form elementary events and structures of meaning. Various aspects of human being are better scrutinized with these concepts of intentionality, such as the association of individual being or collective being (e.g. groups) with the less differentiated anonymity of human being. The aim of our framework is to support the qualitative researcher in grasping the experience of the human life in closer accord with how this being actually unfolds and is lived. Application of the presented framework is illuminated with empirical examples from educational, health and psychological contexts. Finally, we discuss the methodological implications that our approach has for qualitative investigations of human being.
Post-War Reflections on the Ambon War
Authors: van Liere Lucien , van Dis Elizabeth 
Published: October 2018

Abstract
Between 1999 and 2004, with reverberations until 2011, several Moluccan islands (Indonesia) faced violent clashes between Christians and Muslims. Based on 79 interviews, this article seeks to understand how people from both religious groups look back at the conflict, 12 years after the Malino II peace treaty was signed in 2002. We identified three major conflict-related themes that continued to come to the fore during the interviews: explanations about causes of the conflict, religion-related justifications of violence and miracle stories. Most interviewees indicated that the causes of the conflict were non-religious, but rather political. Religion-related language however was frequently used to justify violence as self-defense while miracles-stories were often part of war-narratives. Looking back, Christians and Muslims still understood their communities as injured and victimized. The ‘right to protect’ one’s community as a threatened Christian or Muslim community prevailed in most stories although the source of this threat was not always clear.
A Medieval Muslim Scholar’s Legacy
Authors: Liebrenz Boris 
Published: October 2018

AbstractThis article presents an endowment note as the only surviving material trace from the famous library of the Shiʿite scholar ʿAlī b. Mūsā Ibn Ṭāwūs (589/1193–664/1266). This note offers new insights into the books he possessed and adds clarity about the legal framework under which it was passed on to Ibn Ṭāwūs’ descendants. The article also traces the further history of this manuscript through Damascus to Istanbul and discusses strategies for tracking these notes, which were often willfully destroyed.
A Manuscript of the Last Sultan of al-Andalus and the Fate of the Royal Library of the Nasrid Sultans at the Alhambra
Authors: Ženka Josef 
Published: October 2018

AbstractThis article addresses the fate of the Royal Library of the Nasrid Sultans at the Alhambra. Several royal manuscripts once belonging to the Nasrid sultans of Granada survive to this day, despite having been thought burned by the cardinal Cisneros (d. 1517). One of the volumes is a personal manuscript of the last sultan of al-Andalus, Muḥammad XI (Boabdil; reigned 887–888/1482–1483, 892–897/1487–1492) and is currently held in the Royal Library of the Monastery of San Lorenzo de El Escorial. This codex abounds with manuscript notes telling the story of its creation and its first owner, the Sultan, until it was incorporated into the current collection. The author examines its journey in the context of the Sultan’s life and the Nasrid manuscript and book culture, arguing that it was this ruler who moved the royal books out of the Alhambra to his place of exile in North Africa. The article is accompanied by an edition and translation of an ijāza given to Muḥammad XI by the mufti and khaṭīb of Granada al-Mawwāq (d. 897/1492). It is the sole surviving royal teaching certificate from the Nasrid period of Andalusi history.
100 Years Later: Reflecting on Alfred Wegener’s Contributions to Tornado Research in Europe
Authors: Antonescu Bogdan , Ricketts Hugo M. A. M. , Schultz David M. 
Published: October 2018

AbstractAlfred Wegener (1880–1930) was a leading geophysicist, atmospheric scientist, and an Arctic explorer who is mainly remembered today for his contributions to the theory of continental drift. Less well known are his contributions to research on tornadoes in Europe. Published 100 years ago, Wegener’s 1917 book Wind- und Wasserhosen in Europa (Tornadoes and Waterspouts in Europe) is an impressive synthesis of knowledge on tornadoes and is considered the first modern pan-European tornado climatology, with 258 reports from 1456 to 1913. Unfortunately, Wegener’s book was overlooked after the 1950s amid declining interest in tornadoes by European researchers and meteorologists. The recent revival of tornado studies in Europe invites a reflection on Wegener’s book. Using a relatively small dataset, Wegener was able to describe characteristics of tornadoes (e.g., direction of movement, speed, rotation, formation mechanism), as well as their frequency of occurrence and climatology, comparable with the results from modern tornado climatologies. Wegener’s lasting scientific contributions to tornado research are presented in the context of European research on this topic. Specifically, his book showed the utility of reports from citizen scientists and inspired other researchers, namely, Johannes Letzmann, who continued to study European tornadoes after Wegener’s death.
Space–Time Spectral Analysis of the Moist Static Energy Budget Equation
Authors: Yasunaga Kazuaki , Yokoi Satoru , Inoue Kuniaki , Mapes Brian E. 
Published: October 2018

AbstractThe budget of column-integrated moist static energy (MSE) is examined in wavenumber–frequency transforms of longitude–time sections over the tropical belt. Cross-spectra with satellite-derived precipitation (TRMM-3B42) are used to emphasize precipitation-coherent signals in reanalysis [ERA-Interim (ERAI)] estimates of each term in the budget equation. Results reveal different budget balances in convectively coupled equatorial waves (CCEWs) as well as in the Madden–Julian oscillation (MJO) and tropical depression (TD)-type disturbances. The real component (expressing amplification or damping of amplitude) for horizontal advection is modest for most wave types but substantially damps the MJO. Its imaginary component is hugely positive (it acts to advance phase) in TD-type disturbances and is positive for MJO and equatorial Rossby (ERn1) wave disturbances (almost negligible for the other CCEWs). The real component of vertical advection is negatively correlated (damping effect) with precipitation with a magnitude of approximately 10% of total latent heat release for all disturbances except for TD-type disturbance. This effect is overestimated by a factor of 2 or more if advection is computed using the time–zonal mean MSE, suggesting that nonlinear correlations between ascent and humidity would be positive (amplification effect). ERAI-estimated radiative heating has a positive real part, reinforcing precipitation-correlated MSE excursions. The magnitude is up to 14% of latent heating for the MJO and much less for other waves. ERAI-estimated surface flux has a small effect but acts to amplify MJO and ERn1 waves. The imaginary component of budget residuals is large and systematically positive, suggesting that the reanalysis model’s physical MSE sources would not act to propagate the precipitation-associated MSE anomalies properly.
Idealized Study on the Effect of Bottom Topography on the Seasonality of the Stability of the Iceland–Faeroe Front
Authors: Jiménez-Urias Miguel A. , Thompson LuAnne 
Published: October 2018

AbstractWe investigate the effects of bottom topography on the instability, eddy-driven heat flux, and overturning of a front that sits atop a ridge by varying the initial location of an idealized frontal outcrop with respect to a topographic ridge. The front is periodic in the along-ridge direction and unstable to both mixed layer and mesoscale baroclinic instabilities with both instabilities focused on the northern flank of the ridge where the front outcrops. We find agreement with the theoretical predictions for the development of mesoscale instability of the jet in the presence of sloping bottom topography, and we find the initial growth of surface mixed layer eddies is insensitive to topographic variations. However, during the finite amplitude phase of mixed layer instability, we find faster development of mesoscale eddies and thus a stronger cross-front eddy heat flux and residual circulation for the position of the jet where we found the faster growth of mesoscale baroclinic instability. Over an advective time scale that represents the transit time of a water parcel along the Iceland–Faeroe Ridge (IFR), the resulting eddy heat flux is greatest in the cases where the frontal jet experiences the most destabilizing bottom topography of the three cases tested, with values comparable to the heat flux associated with the mean flow. Therefore, eddy dynamics over the IFR frontal region are important contributors to the heat exchanges between the North Atlantic and Nordic Seas, with the bottom topography playing a key role in determining the largest heat fluxes, whether the initial growth is dominated by mixed layer eddies or mesoscale eddies.
Bevacizumab for Hearing Preservation in Neurofibromatosis Type 2: Emphasis on Patient‐Reported Outcomes and Toxicities
Authors: Sverak Pavlina , Adams Meredith E. , Haines Stephen J. , Levine Samuel C. , Nascene David , Sommer Katherine , Dusenbery Kathryn , Huang Tina C. , Moertel Christopher 
Published: October 2018

ObjectiveBevacizumab for hearing preservation in patients with neurofibromatosis type 2 (NF2) is an emerging practice. We set out to characterize the effectiveness and toxicity of bevacizumab in our patient group.Study DesignCase series with chart review.SettingTertiary referral center.Subjects and MethodsSeventeen consecutive patients with NF2 received bevacizumab treatment for vestibular schwannomas, including 2 patients treated to maintain cochlear implant performance. Volumetric analysis of serial magnetic resonance imaging scans was used to evaluate radiographic response, and hearing response was evaluated with serial audiograms. Patient‐reported outcomes were also assessed, including subjective hearing improvement, changes in tinnitus, vertigo, headaches, ear pain, and improvement in ability to communicate via telephone.ResultsA positive radiographic response occurred in 8 of 17 (47%) patients and the median tumor volume change was a tumor decrease of 19%. A positive hearing response was recorded in 5 of 9 (56%) patients. Two patients had a word recognition score improvement over 40%. There was an approximately 40% improvement in patient‐reported outcomes. Primary toxicities included hypertension, proteinuria, dysgeusia, and amenorrhea.ConclusionBevacizumab treatment was followed by hearing improvement in 56% of patients, while decreased tumor volume was noted in 47%. These outcomes agree favorably with prior reported series. There were significant improvements in patient‐reported outcomes that have not been described previously.
Stenosis of Uretero-Intestinal Anastomoses. Our Experience
Authors: Simonato A. , Bonini F. , Pizzorno R. , Galli S. , Romagnoli A. , Carmignani G. 
Published: October 2018

The main aim of every urinary diversion is to preserve the morphological and functional integrity of the upper urinary tracts. Stenosis of the uretero-intestinal anastomosis is one of the most dreaded complications. This alone may jeopardise the success of the operation and the quality of life that remains for the patient. Material and methods From November ‘94 to December ‘97,109 patients (average age 68 years, range 48–79) underwent radical cystectomy with urinary diversion (53 VIP, 42 Bricker, 4 Reddy2, 3 USS, 2 Studer, 1 Mainz1, 1 Mainz2, 2 Indiana, 1 Camey2). 216 anti-reflux u-i anastomoses were created (93 Le Duc, 6 Leadbetter, 4 Goodwin, 2 Split-cuff, 2 Mainz, 2 Ghoneim) and 107 direct anastomoses (41 Nesbit, 35 Wallace1, 13 Bricker, 12 Polsino, 6 Wallace2). Results 18/216 (8.3%) stenoses occurred (none secondary to neoplastic recurrence): 11/109 (10%) in u-i anastomoses made with the anti-reflux technique (6 Le Duc, 2 Ghoneim, 2 Mainz, 1 Leadbetter) and 7/107 (6.5%) with direct implantation (3 Nesbit, 2 Polsino, 2 Wallace1). Stenoses occurred in 9 VAP, 3 Bricker, 2 Reddy2 (bilateral in 4 patients). Conclusions The high number of variants of uretero-intestinal anastomosis techniques demonstrates that there is as yet no commonly accepted technique, every surgeon performing the procedure that in his experience produces the best results with the fewest complications. The choice of type of anastomosis should take into account the type of urinary diversion with its urodynamic characteristics, searching as far as possible to create anti-reflux mechanisms in the orthotopic diversions. The common principles of surgical technique remain valid, i.e. to respect the anatomical structure, to avoid stretching or curving of the ureter, to create leak-proof anastomoses.