bluuebunny/crossref_metadata_2025_split huggingface dataset:
Policy accommodation versus electoral turnover: policy representation in Britain, 1945–2015
Authors: Bartle John , Avellaneda Sebastian Dellepiane , McGann Anthony 
Published: April 2018

AbstractDoes public policy in the United Kingdom respond to changes in public preferences? If so, is this the result of the government changing its policy to reflect preferences (“policy accommodation”) or the result of governments that pursue unpopular policies being replaced at elections by governments more in line with the public (“electoral turnover”)? We explore these questions by estimating annual aggregate public preferences (“the policy mood”) using responses to 287 questions administered 2,087 times and annual policy using budgetary data (“nonmilitary government expenditure”) for the whole of the postwar period. We find that mood moves in the opposite direction to policy and variations in mood are associated with variations in annual vote intentions. Policy is responsive to party control but not directly responsive to mood. Shifts in mood eventually lead to a change in government and thus policy, but this process may be very slow if the public has doubts about the competence of the opposition.
Seasonal influences on ungulate movement within a fenced South African reserve
Authors: O'Kane Christopher A.J. , Macdonald David W. 
Published: April 2018

Abstract:The movement of African ungulates between habitats is determined by diverse factors including forage composition, availability and quality, water availability, topography, the catenary level and the effect of fire on vegetation. We assessed how grass flushes, following dry-season fires, and availability of water influenced seasonal movements of hartebeest, impala, warthog, white rhino, wildebeest and zebra in Ithala Game Reserve, a fenced reserve in South Africa. Over a 6-d period each month for 4 y, road transects covering a representative sample of the reserve's different vegetation types, and 23% of the reserve's total area, were carried out. We recorded the species, number, sex and age class of herbivores, obtaining 8742 records (total herbivores sighted = 47055), and obtained positional data on sightings over the last 2 y of the study. Using a GIS-based approach, we determined that ruminant, but not non-ruminants, were significantly attracted to dry-season grass flushes, and that presence or absence of such flushes significantly affected their mean distance to water and hence seasonal movements on the catena.
Expected value of high powers of trace of frobenius of biquadratic curves over a finite field
Authors: MEISNER PATRICK 
Published: April 2018

AbstractDenote ΘCas the Frobenius class of a curveCover the finite field 𝔽q. In this paper we determine the expected value of Tr(ΘCn) whereCruns over all biquadratic curves whenqis fixed andgtends to infinity. This extends work done by Rudnick [15] and Chinis [5] who separately looked at hyperelliptic curves and Bucur, Costa, David, Guerreiro and Lowry-Duda [1] who looked at ℓ-cyclic curves, for ℓ a prime, as well as cubic non-Galois curves.
A weighted weak-type bound for Haar multipliers
Authors: Osȩkowski Adam 
Published: April 2018

We study a weighted maximal weak-type inequality for Haar multipliers that can be regarded as a dual problem of Muckenhoupt and Wheeden. More precisely, if Tε is the Haar multiplier associated with the sequence ε with values in [−1, 1], and is the r-maximal operator, then for any weight w and any function f on [0, 1) we havefor some constant Cr depending only on r. We also show that the analogous result does not hold if we replace by the dyadic maximal operator Md. The proof rests on the Bellman function method; using this technique we establish related weighted Lp estimates for p close to 1, and then deduce the main result by extrapolation arguments.
Food pyramid for subjects with chronic pain: foods and dietary constituents as anti-inflammatory and antioxidant agents
Authors: Rondanelli Mariangela , Faliva Milena Anna , Miccono Alessandra , Naso Maurizio , Nichetti Mara , Riva Antonella , Guerriero Fabio , De Gregori Manuela , Peroni Gabriella , Perna Simone 
Published: April 2018

AbstractEmerging literature suggests that diet constituents may play a modulatory role in chronic pain (CP) through management of inflammation/oxidative stress, resulting in attenuation of pain. We performed a narrative review to evaluate the existing evidence regarding the optimum diet for the management of CP, and we built a food pyramid on this topic. The present review also describes the activities of various natural compounds contained in foods (i.e. phenolic compounds in extra-virgin olive oil (EVO)) listed on our pyramid, which have comparable effects to drug management therapy. This review included 172 eligible studies. The pyramid shows that carbohydrates with low glycaemic index should be consumed every day (three portions), together with fruits and vegetables (five portions), yogurt (125 ml), red wine (125 ml) and EVO; weekly: legumes and fish (four portions); white meat, eggs and fresh cheese (two portions); red or processed meats (once per week); sweets can be consumed occasionally. The food amounts are estimates based on nutritional and practical considerations. At the top of the pyramid there is a pennant: it means that CP subjects may need a specific customised supplementation (vitamin B12, vitamin D,n-3 fatty acids, fibre). The food pyramid proposal will serve to guide dietary intake with to the intent of alleviating pain in CP patients. Moreover, a targeted diet can also help to solve problems related to the drugs used to combat CP, i.e. constipation. However, this paper would be an early hypothetical proposal due to the limitations of the studies.
Pulmonary atresia with intact ventricular septum and congenital left ventricular aneurysm
Authors: Ng Benton , Hickok Rhiannon , Stapleton Gary , Karl Tom 
Published: April 2018

AbstractPulmonary atresia with intact ventricular septum and congenital left ventricular aneurysms are both rare, representing <1 and <0.1% of CHD, respectively. The association of left ventricular aneurysms and pulmonary atresia with intact ventricular septum has been documented in the literature, but all the previous case reports have involved children with acquired left ventricular aneurysms. We report an interesting case of a child with both pulmonary atresia with intact ventricular septum and a congenital left ventricular aneurysm. The combination of these two lesions ultimately affected the course of clinical care for the patient.
Three-dimensional echocardiographic evaluation of Ebstein’s anomaly of the tricuspid valve in a patient with hypoplastic left heart syndrome
Authors: Cassidy Courtney , Mitchell Max B. , Jone Pei-Ni 
Published: April 2018

AbstractWe report three-dimensional imaging of a rare finding of Ebstein’s anomaly of the tricuspid valve in a patient with hypoplastic left heart syndrome, which has been previously reported only by two-dimensional echocardiography. A fetal echocardiogram was performed at 19 weeks that showed a moderately hypoplastic left ventricle, severely hypoplastic mitral valve, a severely hypoplastic aortic valve, and a dysplastic tricuspid valve. Post Caesarean delivery at 40 weeks of gestation, a transthoracic echocardiogram confirmed the findings seen on the fetal echocardiogram. A three-dimensional echocardiogram was then performed, which demonstrated an Ebstein tricuspid valve with apical displacement of the septal leaflet, chordal attachments of the valve to the right ventricular outflow tract, and moderate tricuspid regurgitation. The patient underwent a successful heart transplantation.
A protocol to decrease postoperative chylous effusion duration in children
Authors: Winder Melissa M. , Eckhauser Aaron W. , Delgado-Corcoran Claudia , Smout Randall J. , Marietta Jennifer , Bailly David K. 
Published: April 2018

AbstractObjectiveOur primary goal was to decrease time to resolution of postoperative chylothorax as demonstrated by total days of chest tube utilisation through development and implementation of a management protocol.MethodsA chylothorax management protocol was implemented as a quality improvement project at a tertiary-care paediatric hospital in July, 2015. Retrospective analysis was completed on patients aged 0–17 years diagnosed with chylothorax within 30 days of cardiac surgery in a pre-protocol cohort (February, 2014 to June, 2015, n=20) and a post-protocol cohort (July, 2015 to March, 2016, n=22).Measurements and resultsPatient characteristics were similar before and after protocol implementation. Duration of mechanical ventilation and cardiac ICU and hospital lengths of stay were unchanged between cohorts. Following protocol implementation, total duration of chest tube utilisation decreased from 12 to 7 days (p=0.047) with a decrease in maximum days of chest tube utilisation from 44 to 13 days. Duration of medium-chain triglyceride feeds decreased from 42 days to 31 days (p=0.01). In total, three patients in the post-protocol cohort underwent additional surgical procedures to treat chylothorax with subsequent resolution of chylothorax within 24 hours. There were no chest tube re-insertions or re-admissions related to chylothorax in either the pre- or post-protocol cohorts. Protocol compliance was 81%.ConclusionsAdoption of a chylothorax management protocol is feasible, and in our small cohort of patients implementation led to a significant decrease in the duration of chest tube utilisation, while eliminating practice variability among providers.
Left ventricular mass of persistent masked hypertension in Hong Kong Chinese adolescents: a 4-year follow-up study
Authors: Yam Man-Ching , So Hung-Kwan , Kwok Sit-Yee , Lo Fung-Cheung , Mok Chi-Fung , Leung Chuk-Kwan , Yip Wai-Kwok , Sung Yn-Tz 
Published: April 2018

AbstractObjectiveIn our previous study, the prevalence of childhood masked hypertension was 11%. This study aims to assess the left ventricular mass index of persistent masked hypertension and determine the factors of elevated left ventricular mass index in Hong Kong Chinese adolescents from a community cohort.DesignCommunity prospective cohort study, follow-up of a case-control study in community.SubjectsPatients with masked hypertension at baseline were invited to recheck ambulatory blood pressure for the persistence of masked hypertension.ResultsA total of 144 out of 165 patients with masked hypertension in the 2011/2012 ambulatory blood pressure survey consented to participate in the study. In all, 48 patients were found to have persistent masked hypertension by ambulatory blood pressure rechecking and were matched with normotensive controls by sex, age, and body height. The left ventricular mass (117.3±39.9 g versus 87.0±28.2 g versus 102.0±28.2 g) and left ventricular mass index (30.1±8.4 g/m2.7 versus 23.9±6.3 g/m2.7 versus 25.1±5.7 g/m2.7) were significantly higher in the persistent masked hypertension group (p<0.0001) compared with the patients without persistent masked hypertension and controls. In multivariate linear regression analysis, left ventricular mass index was found to be higher in male gender (β=4.874, p<0.0001) and the patients with persistent masked hypertension (β=2.796, p=0.003). In addition, left ventricular mass index was positively associated with body mass index z-score (β=3.045, p<0.0001) and low-density lipoprotein cholesterol concentration (β=1.634, p=0.015).ConclusionsPersistent masked hypertension in adolescents is associated with elevated left ventricular mass index.
Aspect opinion expression and rating prediction via LDA–CRF hybrid
Authors: LADDHA ABHISHEK , MUKHERJEE ARJUN 
Published: April 2018

AbstractIn this paper, we study the problem of aspect-based sentiment analysis. Our model simultaneously extracts aspect-specific opinion expressions and determines the rating for each aspect in reviews. Previous works have mainly focused on the problem of opinion phrase extraction and aspect rating prediction in a pipelined manner and are not able to capture the dependencies of aspect opinion expression on aspect rating and vice-versa. They are also unable to discover aspect-specific opinion expressions and their associated rating scores. We present a joint modelling approach to extract aspect-specific sentiment expression and aspect rating prediction simultaneously. This paper proposes a novel LDA–CRF hybrid model which employs discriminative conditional random field component for phrase extraction, a regression component for rating prediction and a generative component for grouping aspect–sentiment expressions (aspect-specific opinion expressions) into coherent topics. To show the effectiveness of our approach, we evaluate the performance of the model on both task: (i) aspect-specific opinion expressions and (ii) rating prediction on the dataset of hotel and restaurant reviews from TripAdvisor.com. Experimental results show that both task potentially reinforce each other and joint modeling outperformed state-of-the-art baselines for each individual tasks.
A national FFQ for the Netherlands (the FFQ-NL1.0): development and compatibility with existing Dutch FFQs
Authors: Eussen Simone JPM , van Dongen Martien CJM , Wijckmans Nicole EG , Meijboom Saskia , Brants Henny AM , de Vries Jeanne HM , Bueno-de-Mesquita H Bas , Geelen Anouk , Sluik Diewertje , Feskens Edith JM , Ocké Marga C , Dagnelie Pieter C 
Published: April 2018

AbstractObjectiveIn the Netherlands, various FFQs have been administered in large cohort studies, which hampers comparison and pooling of dietary data. The present study aimed to describe the development of a standardized Dutch FFQ, FFQ-NL1.0, and assess its compatibility with existing Dutch FFQs.DesignDutch FFQTOOLTM was used to develop the FFQ-NL1.0 by selecting food items with the largest contributions to total intake and explained variance in intake of energy and thirty-nine nutrients in adults aged 25–69 years from the Dutch National Food Consumption Survey (DNFCS) 2007–2010. Compatibility with the Maastricht-FFQ, Wageningen-FFQ and EPICNL-FFQ was assessed by comparing the number of food items, the covered energy and nutrient intake, and the covered variance in intake.ResultsFFQ-NL1.0 comprised 160 food items, v. 253, 183 and 154 food items for the Maastricht-FFQ, Wageningen-FFQ and EPICNL-FFQ, respectively. FFQ-NL1.0 covered ≥85 % of energy and all nutrients reported in the DNFCS. Covered variance in intake ranged from 57 to 99 % for energy and macronutrients, and from 45 to 93 % for micronutrients. Differences between FFQ-NL1.0 and the other FFQs in covered nutrient intake and covered variance in intake were <5 % for energy and all macronutrients. For micronutrients, differences between FFQ-NL and other FFQs in covered level of intake were <15 %, but differences in covered variance were much larger, the maximum difference being 36 %.ConclusionsThe FFQ-NL1.0 was compatible with other FFQs regarding energy and macronutrient intake. However, compatibility for covered variance of intake was limited for some of the micronutrients. If implemented in existing cohorts, it is advised to administer the old and the new FFQ in combination to derive calibration factors.
Rolled Winter Rye–Hairy Vetch Cover Crops for Weed Control in No-till Pumpkin
Authors: Miville David , Leroux Gilles D. 
Published: April 2018

AbstractWeed control is a challenging aspect of pumpkin production. Winter rye mulches may offer growers a means to manage weeds in pumpkin; however, rye degradation leads to an immobilization of soil nitrogen. Combining winter rye with a nitrogen fixing legume such as hairy vetch is an interesting option that may solve this problem. Twelve combinations including three hairy vetch seeding rates, two termination dates and the use or not of glyphosate before rolling cover crops were studied during the 2013 and 2014 growing seasons at the Laval University Agronomic Station in Saint-Augustin-de-Desmaures, Quebec, Canada to evaluate weed control and effects on pumpkin production. Adding hairy vetch to winter rye provided no benefits because of severe winterkill of the legume. Using glyphosate was necessary to prevent rye regrowth. Pumpkin growth was better and yields were higher than in the plots were no glyphosate was used. Mulches established at flowering (Zadoks 69) provided about 2,000 kg ha−1 more aboveground dry biomass than at early heading (Zadoks 51). This high biomass was essential in glyphosate treated plots in order to maintain excellent weed control throughout the growing season. When compared with the no-mulch weed-free control, yield in Zadoks 69+glyphosate treatment was lower in 2013 but comparable in 2014.
Waldenström macroglobulinemia treatment algorithm 2018
Authors: Gertz Morie A. 
Published: April 2018

AbstractWaldenström macroglobulinemia is often an indolent disorder, and many patients are candidates for observation with careful monitoring. For symptomatic patients, one must distinguish between those patients whose symptoms are related to immunologic manifestations associated with the IgM monoclonal protein and those that have symptoms related to progressive marrow and nodal infiltration with lymphoplasmacytic lymphoma. In Waldenström macroglobulinemia, the driver for therapy in the majority of patients is progressive anemia, secondary to bone marrow replacement by lymphoplasmacytic lymphoma. Recent introduction of MYD88 mutational analysis has been very useful for diagnostic purposes but is unclear what effect it might have on the prognosis or response rate to therapy. An algorithm is provided on the management of asymptomatic individuals and the sequence used for chemotherapeutic intervention of symptomatic patients.
Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies
Authors: Guo Qiang , Wang Yuxiang , Xu Dan , Nossent Johannes , Pavlos Nathan J. , Xu Jiake 
Published: April 2018

AbstractRheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily affects the lining of the synovial joints and is associated with progressive disability, premature death, and socioeconomic burdens. A better understanding of how the pathological mechanisms drive the deterioration of RA progress in individuals is urgently required in order to develop therapies that will effectively treat patients at each stage of the disease progress. Here we dissect the etiology and pathology at specific stages: (i) triggering, (ii) maturation, (iii) targeting, and (iv) fulminant stage, concomitant with hyperplastic synovium, cartilage damage, bone erosion, and systemic consequences. Modern pharmacologic therapies (including conventional, biological, and novel potential small molecule disease-modifying anti-rheumatic drugs) remain the mainstay of RA treatment and there has been significant progress toward achieving disease remission without joint deformity. Despite this, a significant proportion of RA patients do not effectively respond to the current therapies and thus new drugs are urgently required. This review discusses recent advances of our understanding of RA pathogenesis, disease modifying drugs, and provides perspectives on next generation therapeutics for RA.
High prevalence of diabetes among migrants in the United Arab Emirates using a cross-sectional survey
Authors: Sulaiman Nabil , Albadawi Salah , Abusnana Salah , Mairghani Maisoon , Hussein Amal , Al Awadi Fatheya , Madani Abdulrazak , Zimmet Paul , Shaw Jonathan 
Published: April 2018

AbstractIn 2011, the United Arab Emirates (UAE) had the 10th highest diabetes prevalence globally, but this was based on data that excluded migrants who comprise 80% of the population. This study assessed diabetes prevalence across the UAE population. A random sample of migrants was recruited from the visa renewal centers. Data were collected using interviews, anthropometric measurements and fasting blood for glucose, lipids and genetic analyses. 2724 adults completed the questionnaires and blood tests. Of these, 81% were males, 65% were ≤40 years old and 3% were above 60 years. Diabetes, based on self-report or fasting plasma glucose ≥7.0 mmol/l, showed a crude prevalence of 15.5%, of whom 64.2% were newly diagnosed. Overall age- and sex-adjusted diabetes prevalence, according to the world mid-year population of 2013, was 19.1%. The highest prevalence was in Asians (16.4%) and non-Emirati Arabs (15.2%) and lowest in Africans and Europeans (11.9%). It increased with age: 6.3% in 18–30 years and 39.7% in 51 to 60 years. Lower education, obesity, positive family history, hypertension, dyslipidemia, snoring, and low HDL levels, all showed significant associations with diabetes. The high diabetes prevalence among migrants in the UAE, 64% of which was undiagnosed, necessitates urgent diabetes prevention and control programs for the entire UAE population.
Chicken Interferon-induced Protein with Tetratricopeptide Repeats 5 Antagonizes Replication of RNA Viruses
Authors: Santhakumar Diwakar , Rohaim Mohammed Abdel Mohsen Shahaat , Hussein Hussein A. , Hawes Pippa , Ferreira Helena Lage , Behboudi Shahriar , Iqbal Munir , Nair Venugopal , Arns Clarice W. , Munir Muhammad 
Published: April 2018

AbstractThe intracellular actions of interferon (IFN)-regulated proteins, including IFN-induced proteins with tetratricopeptide repeats (IFITs), attribute a major component of the protective antiviral host defense. Here we applied genomics approaches to annotate the chicken IFIT locus and currently identified a single IFIT (chIFIT5) gene. The profound transcriptional level of this effector of innate immunity was mapped within its unique cis-acting elements. This highly virus- and IFN-responsive chIFIT5 protein interacted with negative sense viral RNA structures that carried a triphosphate group on its 5′ terminus (ppp-RNA). This interaction reduced the replication of RNA viruses in lentivirus-mediated IFIT5-stable chicken fibroblasts whereas CRISPR/Cas9-edited chIFIT5 gene knockout fibroblasts supported the replication of RNA viruses. Finally, we generated mosaic transgenic chicken embryos stably expressing chIFIT5 protein or knocked-down for endogenous chIFIT5 gene. Replication kinetics of RNA viruses in these transgenic chicken embryos demonstrated the antiviral potential of chIFIT5 in ovo. Taken together, these findings propose that IFIT5 specifically antagonize RNA viruses by sequestering viral nucleic acids in chickens, which are unique in innate immune sensing and responses to viruses of both poultry and human health significance.