bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors associated with low birth weight in low-income populations in the Western Balkans: insights from the multiple indicator cluster survey
Authors: Grbic Dragana , Supic Zorica Terzic , Todorovic Jovana , Nesic Dejan , Karic Svetlana , Jurisic Aleksandar , Kocic Sanja , Bukumiric Zoran , Cirkovic Andja , Jankovic Svetlana 
Published: December 2024

IntroductionLow birth weight, defined as a birth weight below 2,500 g, represents a significant public health concern with a multifactorial risk dimension. Socio-demographic factors and individual characteristics of women and their social environment could influence low birth weight. This study aimed to analyze the association between the socio-demographic and reproductive characteristics of women living in low-income households and low birth weight in Serbia, Kosovo, and Montenegro.MethodsThis study was conducted as secondary data analysis during the Multiple Indicator Cluster Survey – Round 6 in Serbia, Kosovo, and Montenegro. The household questionnaire and the individual questionnaire for women aged 15–49 were used as standard research instruments. We analyzed 1,019 women whose households belonged to the first (poorest) or second (poor) wealth index quintiles and who had given birth to a live child within the 2 years preceding the study. A multivariate logistic regression was applied with low birth weight in newborns as the outcome variable.ResultsThe univariate regression analysis showed that women with low birth weight newborns were significantly more likely to live in settlements mainly inhabited by Roma, reside in urban areas, marry or enter a union before age 18, have lower education levels, experience higher illiteracy rates, and receive antenatal care not provided by a medical doctor compared to women whose newborns weighed 2.5 kg or more. A multivariate logistic regression model with a low birth weight of newborns as an outcome variable showed the association between women’s illiteracy (OR: 1.741; 95% CI: 1.060–2.859) and antenatal care not provided by a medical doctor (OR: 2.735; 95% CI: 1.229–6.087).DiscussionIlliteracy and limited access to medical doctor services during pregnancy were factors that increased the likelihood of low birth weight in newborns born to women living in low-income households in the selected Western Balkans populations. The cross-sectional design of this study does not allow the establishment of causal relationships among variables, but it can provide important evidence for future prevention strategies. Interventions are needed to enhance the education of women and to improve access to antenatal care across Serbia, Kosovo, and Montenegro.
The role of parental child marriage in children's food security and nutritional status: a prospective cohort study in Indonesia
Authors: Hidayah Isnawati , Suryahadi Asep , Palmisano Flaviana , Kiefte-de Jong Jessica C. 
Published: December 2024

ObjectivesAssessing children's food and nutrition security in Indonesia, especially among children from parents who experienced child marriage, is crucial for policymakers. This study investigates the role of parental child marriage in children's food security and nutritional status.MethodsWe analyze data from Indonesia Family Life Survey (IFLS) wave 4 (2007) and 5 (2014), involving 1,612 households. We employ OLS and binary logit regression analysis.ResultsOur analysis reveals that parental child marriage is associated with higher probability of children being stunted and experiencing food insecurity. Additionally, parental child marriage correlates with higher BMI-for-age z-scores, which increase the risk of obesity, and lower Food Consumption Scores (FCS).RecommendationImplementing community initiatives, economic empowerment, healthcare access, and gender-sensitive and integrated policies is crucial for enhancing food security and improving nutritional status among childen in families affected by child marriage.
The impact of positive activities on mental health: the mediating role of positive emotion
Authors: Wang Yanting , Wu Yuanyang , Xu Qianqian , Fan Si , Hu Jinwen , Zou Dongdong , Zhang Xinping 
Published: December 2024

ObjectiveMental health has become a widely concerned topic worldwide. However, the impact and mechanism of positive activities on mental health still needed to be explored. This study aimed to apply the positive-activity model to investigate the effect of participation in positive activities on mental health and the mediating role of positive emotion.MethodsThis study used data from the 2021 China Comprehensive Social Survey (CGSS) and included 2,581 individuals. Ordinary Least Squares (OLS) and a three-step method was used for analysis.ResultsThe average of positive activities was 15.83. The positive activities affected positively mental health (β = 0.0132, p &lt; 0.001). The positive emotion played a mediating role (β =0.2281, p &lt; 0.001). The effect of positive activities on mental health was significant in older adults group (β = 0.024, p &lt; 0.001), female (β = 0.015, p &lt; 0.01) and male group (β = 0.01, p &lt; 0.01), unmarried/divorced/widowed group (β = 0.024, p &lt; 0.01), cohabitation/first marriage with spouse/remarriage with spouse/separation without divorce group (β = 0.010, p &lt; 0.001), middle(β = 0.013, p &lt; 0.05), and upper-middle-level SES group (β = 0.054, p &lt; 0.001).ConclusionsWe concluded that the participation level of positive activities still needs to be improved and positive activities improve mental health through positive emotion, which implied that positive activities, as an easily implementable measure, should be greatly encouraged in mental health policies. And older adults, female, people without spouse, middle and upper-middle-income individuals need to be paid more attention.
Birthing parent perspectives on measuring the quality of perinatal care: metrics, timing, and process
Authors: Tully Kristin P. 
Published: December 2024

ObjectiveCentering birthing parents is critical for improving reproductive health policies and practices. This study investigates patient perspectives on measuring the quality of perinatal care.MethodsA cross-sectional qualitative research study was conducted at an academic medical center in the Southeastern United States. Individuals who had recently given birth participated in audio-recorded interviews between May 2020 and September 2020. This analysis addresses the research question, “If we were providing quality healthcare for families, how would we know?” Transcribed and translated responses were inductively coded to develop categories and identify themes.ResultsForty birthing parents participated in the study. Metrics, timing, and process were identified as important components of meaningfully measuring the quality of perinatal care. Recommended metrics included asking patients whether their health priorities were addressed. Additional metrics of importance were whether coping strategies were provided, the clarity of information provided, patient comprehension of health information, the extent to which care planning was collaborative among patients and their healthcare team members, whether clinicians alleviated patient doubts, patient feelings of being taken care of, healthcare team mannerisms, clinician demonstrations of respect for patient autonomy, and postpartum visit attendance. With regard to timing, patients desired that their healthcare team members “check-in” with them as part of an ongoing, direct dialog. Birthing parents also wanted opportunities to provide feedback soon after encounters. As part of a robust measurement process, they wanted to share their insights with someone who was not a part of their healthcare team, for maintaining confidentiality. The patients desired a “serious platform” with accessible methods for all birthing parents to be able to convey nuanced accounts of their care. They also wanted to hear from the healthcare institutions about their feedback. Birthing parents sought assurances for their perinatal care feedback to be de-identified to protect them from potential retaliation. The participants recognized that they might need to utilize healthcare services from the same institution and individuals in the future.ConclusionBirthing parents expressed desire for their perinatal healthcare experiences to be understood. Meaningful quality measurement may be promoted through transparent and multimethod opportunities for patients to securely share insights. In addition to healthcare systems communicating assurances of patient confidentiality, institutional feedback in response to patient-reported experiences is recommended.
Global, regional, and national burden of HIV and tuberculosis and predictions by Bayesian age-period-cohort analysis: a systematic analysis for the global burden of disease study 2021
Authors: Tian Xuebin , Wang Chong , Hao Zhihao , Chen Jingjing , Wu Nanping 
Published: December 2024

ObjectiveTo assess sex, age, regional differences, and the changing trend in human immunodeficiency virus and tuberculosis (HIV-TB) in different regions from 1990 to 2021, and project future trends.MethodsGlobal Burden of Disease Study 2021 data were analyzed to assess HIV-TB incidence, death, prevalence, and DALY rates from 1990 to 2021, including different types of TB co-infections (drug-susceptible, multidrug-resistant, and extensively drug-resistant). Bayesian age-period-cohort models were used to forecast age-standardized DALY rates through 2035.ResultsIn 2021, there were approximately 1.76 million HIV-TB infections and 200,895 deaths globally. The highest burden of HIV-DS-TB and HIV-MDR-TB was found in Southern Sub-Saharan Africa, while HIV-XDR-TB was most prevalent in Eastern Europe. The co-infection burden was highest among individuals aged 30–49. Key risk factors were unsafe sex, drug use, and intimate partner violence, with regional variations. The global burden of HIV-TB remains high, and age-standardized DALY rates are expected to increase in the coming years, especially in regions with low socio-demographic indices (SDI).ConclusionThe burden of HIV-TB co-infection correlates with the socio-demographic index (SDI): countries with a low SDI have a higher burden. Therefore, clinical diagnosis and treatment in such areas are more challenging and may warrant more attention. High death rates underscore the importance of early management.
Enhanced Chondrogenic Differentiation of Electrically Primed Human Mesenchymal Stem Cells for the Regeneration of Osteochondral Defects
Authors: Yi Jongdarm , Byun Yujin , Kang Seong Soo , Shim Kyung Mi , Jang Kwangsik , Lee Jae Young 
Published: December 2024

Background:
Mesenchymal stem cells (MSCs) offer a promising avenue for cartilage regeneration; however, their therapeutic efficacy requires substantial improvement. Cell priming using electrical stimulation (ES) is a promising approach to augmenting the therapeutic potential of MSCs and has shown potential for various regenerative applications. This study aimed to promote the ES-mediated chondrogenic differentiation of human MSCs and facilitate the repair of injured articular cartilage.
Methods:
MSCs were subjected to ES under various conditions (e.g., voltage, frequency, and number of repetitions) to enhance their capability of chondrogenesis and cartilage regeneration. Chondrogenic differentiation of electrically primed MSCs (epMSCs) was assessed based on gene expression and sulfated glycosaminoglycan production, and epMSCs with hyaluronic acid were transplanted into a rat osteochondral defect model. Transcriptomic analysis was performed to determine changes in gene expression by ES.
Results:
epMSCs exhibited significantly increased chondrogenic gene expression and sulfated glycosaminoglycan production compared with those in unstimulated controls. Macroscopic and histological results showed that in vivo epMSC transplantation considerably enhanced cartilage regeneration. Furthermore, ES markedly altered the expression of numerous genes of MSCs, including those associated with the extracellular matrix, the Wnt signaling pathway, and cartilage development.
Conclusion:
ES can effectively prime MSCs to improve articular cartilage repair, offering a promising strategy for enhancing the efficacy of various MSC-based therapies.
Profil Pasien dengan Gangguan Elektrolit yang Dirawat di Ruang Perawatan Intensif
Authors: Sumule Vania S. P. , Laihad Mordekhai L. , Kambey Barry I. 
Published: December 2024

Abstract: Electrolyte disturbance is a common health problem in critical patients in the Intensive Care Unit (ICU). These disorders can cause serious complications and contribute to increased morbidity and mortality. This study aimed to determine the description of electrolyte disturbances experienced by patients in the ICU of Prof. Dr. R. D. Kandou Hospital. This was an observational study with a retrospective design involving 252 patients admitted to the ICU with electrolyte disturbances from January to June 2023. Data were obtained from medical records and analyzed descriptively. The results showed that hyponatremia was the most common electrolyte disorder (65.1%), followed by hypokalemia (48%), hypochloremia (53.6%), hypocalcemia (61.5%), and hyperphosphatemia (40.5%). The highest incidence was in the age group >65 years (18.7% for hyponatremia and hypocalcemia). The majority of patients were male. The most common disease diagnosis was sepsis. In conclusion, hyponatremia and hypocalcemia are the main electrolyte disorders in critical patients in the ICU of Prof. Dr. R. D. Kandou Hospital. The high-risk group is elderly men with sepsis. Close monitoring of electrolytes needs to be done especially in patients with these conditions to prevent fatal complications.
Keywords: electrolyte disturbance; hyponatremia; hypocalcemia

Abstrak: Gangguan elektrolit merupakan masalah yang sering terjadi pada pasien kritis di Intensive Care Unit (ICU). Penelitian ini bertujuan mengetahui profil pasien dengan gangguan elektrolit di ICU RSUP Prof. Dr. R. D. Kandou. Jenis penelitian ialah observasional retrospektif dan pendekatan kuantitatif. Sampel penelitian ialah 252 pasien dengan gangguan elektrolit yang dirawat di ICU RSUP Prof. Dr. R. D. Kandou periode Januari-Juni 2023. Pengambilan sampel dilakukan secara purposive sampling. Variabel yang diteliti meliputi jenis gangguan elektrolit, karakteristik pasien (usia, jenis kelamin), diagnosis penyakit, dan lama rawat inap. Data dikumpulkan dari rekam medis dan dianalisis secara deskriptif. Hasil penelitian mendapatkan gangguan elektrolit terbanyak ialah hiponatremia (65,1%) dan hipokalsemia (61,5%). Kelompok usia >65 tahun (18,7%) dan laki-laki lebih banyak mengalami gangguan elektrolit, dan diagnosis tersering ialah sepsis. Rerata lama rawat inap pasien 1-7 hari. Simpulan penelitian ini ialah hiponatremia dan hipokalsemia merupakan gangguan elektrolit yang paling umum terjadi pada pasien ICU RSUP Prof. Dr. R. D. Kandou. Pasien usia lanjut dan sepsis berisiko tinggi mengalami gangguan elektrolit.
Kata kunci: gangguan elektrolit; hiponatremia; hipokalsemia
Hubungan Tingkat Pengetahuan Kesehatan Reproduksi dengan Perilaku Personal Hygiene Saat Mentsruasi pada Remaja Putri Kelas VII di SMP 1 Darul Minin
Authors: Hardiati Iis 
Published: December 2024

Latar Belakang : WHO mengungkapkan sekitar 11.501.707 remaja Perempuan di Indonesia berusia 10-14 tahun, dengan data kesehatan reproduksi di kota Bekasi sebanyak 46% siswi mengalami masalah kesehatan pada siklus menstruasi tidak teratur, gangguan menstruasi seperti nyeri perut yang parah, keputihan dan gatal sekitar area kemaluan. Infeksi saluran kemih pada remaja dan dewasa muda menunjukkan angka yang cukup tinggi secara global, berkisar antara 35% hingga 42% pada remaja dan 27% hingga 40% pada dewasa muda. Beberapa infeksi yang umum terjadi meliputi candidiasis dengan prevalensi sekitar 25% hingga 50%, bacterial vaginosis sekitar 20% hingga 40%, dan trichomoniasis sekitar 5% hingga 15%. Tujuan Penelitian : Mengetahui hubungan tingkat pengetahuan kesehatan reproduksi dengan perilaku personal hygiene saat menstruasi pada remaja putri kelas VII di SMPI Darul Mu,minin 2024. Metode Penelitian : Penelitian ini adalah penelitian kuantitatif dengan desain deskriptif menggunakan metode cross-sectional. Sampel yang akan digunakan pada penelitian ini yaitu Probability total sampling sebanyak 55 responden. Teknis analisa data menggunakan analisis univariat dan analisis bivariat menggunakan uji chi-square (X2) program SPSS versi 26. Hasil Penelitian : Dari 55 responden yang berusia 13 tahun sebanyak 37 orang (67,3%) dan berusia 14 tahun sebanyak 18 responden (32,7%). Yang memiliki pengetahuan baik sebanyak 41 responden (74,5%) dan yang memiliki perilaku personal hygiene saat menstruasi yang baik sebanyak 13 responden (23,6%). Adanya hubungan antara tingkat pengetahuan kesehatan reproduksi dengan perilaku personal hygiene saat menstruasi (p value = 0,007). Kesimpulan dan Saran : Perilaku personal hygiene saat menstruasi merupakan faktor yang signifikan terhadap pengetahuan kesehatan reproduksi remaja. Diharapkan bagi civitas pendidikan meningkatkan lagi sarana kepustakaan dan menambah wawasan dan pengetahuan terkait informasi kesehatan reproduksi bagi siswa/i nya.
Hubungan Kepatuhan Minum Obat Terhadap Penderita Hipertensi di Wilayah Kp. Rawadas RW. 03 Kelurahan Pondok Kopi Kecamatan Duren Sawit Jakarta
Authors: Cusamrih  
Published: December 2024

Hipertensi menjadi salah satu masalah utama kesehatan diseluruh dunia, baik di negara maju maupun di negara berkembang. Disetiap tahunnya kejadian hipertensi mengalami peningkatan terus-menerus (Chasanah & Sugiman, 2022). Kepatuhan lansia dalam minum obat antihipertensi menjadi salah satu faktor penentu dalam mengendalikan tekanan darah. Berdasarkan alasan di atas penulis tertarik mengambil judul diatas dengan Kepatuhan Minum Obat Terhadap Penderita Hipertensi di Wilayah Kp. Rawadas RW. 03 Kelurahan Pondok Kopi Kecamatan Duren Sawit Jakarta Timur. Tujuan penelitian ini yaitu untuk mengetahui Hubungan Kepatuhan Minum Obat Terhadap Penderita Hipertensi. Desain penelitian yang digunakan adalah bersifat analitik dengan pendekatan cross sectional, dimana data yang berhubungan dengan variabel dependen dan variabel independen dilakukan pada waktu yang bersamaan dengan menggunakan kuesioner. Penelitian ini menggunakan data primer dan sekunder dimana variabel bebasnya adalah kepatuhan dan variabel terikatnya minum obat pada hipertensi. Hasil penelitian menunjukan Tidak ada hubungan bermakna antara usia dengan kepatuhan minum obat hipertensi dengan p value 0,894 (p>0,05). Tidak ada hubungan bermakna antara jenis kelamin dengan kepatuhan minum obat hipertensi dengna p value 0,523 (p>0,05).Dari hasil penelitian yang telah dilaksanakan bahwa diketahui Tidak ada hubungan bermakna antara usia dengan kepatuhan minum obat hipertensi dengan p value 0,894 (p>0,05). Dari hasil penelitian yang telah dilaksanakan bahwa diketahui Tidak ada hubungan bermakna antara usia dengan kepatuhan minum obat hipertensi dengan p value 0,894 (p>0,05). Tidak ada hubungan bermakna antara jenis kelamin dengan kepatuhan minum obat hipertensi dengna p value 0,523 (p>0,05).
Hubungan Self Care dan Motivasi dengan Kualitas Hidup pada Pasien Gagal Jantung, Gagal Ginjal Kronik, Diabetes Mellitus dan Stroku Di RS Anna Medika
Authors: Cusamrih  
Published: December 2024

Noncommunicable Diseases Country Profiles, menunjukkan bahwa angka kematian akibat PTM mencapai 71% dari semua kematian di dunia atau sekitar 41 juta orang setiap tahun. Proporsi kematian pada orang dewasa muda (usia 30-69 tahun) lebih tinggi karena faktor PTM yakni sekitar 75% yang menunjukkan bahwa kejadian penyakit ini tidak hanya menjadi masalah pada populasi yang lebih tua PTM yang mengalami peningkatan prevalensi berdasarkan hasil penelitian Riskesdas tahun 2013 dan 2018 di Indonesia yaitu asma, kanker, stroke, ginjal kronis, diabetes mellitus, dan obesitas sentral. Kualitas hidup yang buruk bisa memperburuk kondisi suatu penyakit, begitu juga suatu penyakit dapat memperburuk kualitas hidup penderita. Tujuan Penelitian : Mengetahui Hubungan Self Care dan Motivasi dengan Kualitas Hidup Pasien Gagal Jantung, Gagal Ginjal Kronik, Diabetes Melitus, dan Stroke di RS Anna Medika Tahun 2020.Metode Penelitian : Penelitian ini merupakan penelitian kuantitatif dengan desain analitik korelasi. Metode sampling pada penelitian ini menggunakan teknik random sampling, dengan sampel pasien gagal jantung, gagal ginjal kronik, diabetes mellitus, dan stroke yang berobat ke RS Anna Medika Bekasi. Hasil Penelitian : Hasil penelitian menyimpulkan adanya hubungan signifikan antara self care dengan kualitas hidup pada pasien gagal jantung (p: 0,000), ada hubungan yang signifikan antara motivasi dengan kualitas hidup pasien gagal jantung (p: 0,000), ada hubungan signifikan antara self care dengan kualitas hidup pada pasien gagal ginjal kronik (p: 0,001), ada hubungan yang signifikan antara motivasi dengan kualitas hidup pada pasien gagal ginjal kronik (p: 0,003), ada hubungan signifikan antara self care dengan kualitas hidup pada pasien diabetes melitus (p: 0,001), ada hubungan yang signifikan antara motivasi dengan kualitas hidup pada pasien diabetes melitus (p: 0,024), ada hubungan signifikan antara self care dengan kualitas hidup pada pasien stroke (p: 0,000), ada hubungan yang signifikan antara motivasi dengan kualitaspada hidup pasien stroke (p: 0,016) Kesimpulan dan Saran : Adanya hubungan self care dan motivasi terhadap kualitas hidup pasien gagal jantung, gagal ginjal kronik, diabetes melitus, dan stroke di RS Anna Medika Tahun 2024. Diharapkan dengan hasil penelitian ini pasien dengan penyakit gagal jantung, gagal ginjal kronik, diabetes melitus, dan stroke, dapat menerapkan self care dengan rutin serta memiliki motivasi yang kuat sehingga akan meningkatkan kualitas hidup mereka.
Modeling Multiple X-Ray Reflection in Super-Eddington Winds
Authors: Zhang 张 Zijian 子健 , Thomsen Lars Lund , Dai Lixin , Reynolds Christopher S. , García Javier A. , Kara Erin , Connors Riley , Masterson Megan , Yao Yuhan , Dauser Thomas 
Published: December 2024

Abstract
It has been recently discovered that a few super-Eddington sources undergoing black hole super-Eddington accretion exhibit X-ray reflection signatures. In such new systems, one expects the coronal X-ray emissions to be mainly reflected by optically thick super-Eddington winds instead of thin disks. In this paper, we conduct a series of general-relativistic ray-tracing and Monte Carlo radiative transfer simulations to model the X-ray reflection signatures, especially the characteristic Fe Kα line, produced from super-Eddington accretion flows around nonspinning black holes. In particular, we allow the photons emitted by a lamppost corona to be reflected multiple times in a cone-like funnel surrounded by fast winds. We find that the Fe Kα line profile most sensitively depends on the wind kinematics, while its exact shape also depends on the funnel open angle and corona height. Furthermore, very interestingly, we find that the Fe Kα line can have a prominent double-peak profile in certain parameter spaces, even with a face-on orientation. Moreover, we compare the Fe Kα line profiles produced from super-Eddington and thin disks and show that such lines can provide important insights into the understanding of black hole systems undergoing super-Eddington accretion.