bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relationship between Pregnancy Exercise and the Level of Anxiety of Pregnant Women in Confronting Normal Childbirth at the Kartasura Health Center Work Area
Authors: Anggraini Putri Nurlia , Sulastri Sulastri , Sulastri Sulastri , Sulastri Sulastri 
Published: December 2024

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p><em> </em></p><p><em>The first of the psychological issues that pregnant women frequently face, particularly during the third trimester, is anxiety related to typical labor. Pregnancy exercises are among the non-pharmacological strategies that can be used to lessen anxiety. The purpose of this study is to ascertain how pregnant women's anxiety levels at the Kartasura Health Center working area relate to their prenatal exercise regimens. This study employed a cross-sectional design and a quantitative methodology. The research was conducted in the working area of the Kartasura Health Center which was carried out in August 2024. The population of this study were all third trimester pregnant women in the Kartasura Health Center area as many as 258. The sample technique used purposive sampling so that the sample in this study was 72. Data collection for this study used demographic questionnaires and PASS (Perinatal Anxiety Screening Scale) anxiety questionnaires. Data analysis in this study with Descriptive Univariate and Bivariate analysis with Chi-Square test. The results showed that pregnant gymnastics has a relationship with reducing anxiety and smoothness in facing the normal labor process at the Kartasura Health Center (p-value-0.036). It is expected that medical professionals can increase the pregnant exercise program and reduce maternal morbidity. Pregnant exercises can be included in the childbirth preparation program at the Kartasura Health Center to help pregnant women face childbirth more calmly.</em></p><p><em> </em></p></td></tr></tbody></table></div><strong><em>Keywords: Pregnancy Exercise, Anxiety, Third Trimester Pregnant Women</em></strong>
The Influence Functional Status on The Quality Life Post Patients Stroke
Authors: Sitohang Tiur Romatua , Manik Herlina Evi Yanti 
Published: December 2024

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p><em>Stroke is a functional brain disorder that occurs suddenly and is characterised by clinical symptoms both vocal and global which persist for a period exceeding 24 hours. These symptoms are caused by disorders affecting the blood circulation system. In patients who have suffered a stroke can result in difficulties for carrying out activities of daily living and in the development of motor skills. The research design was a correlational observational study with a cross-sectional approach. The study sample comprised 30 post-stroke patients. Inclusion criteria were patients post-stroke one year or more, seeking outpatient treatment at the Neurology Clinic from June to August 2024. Sampling was conducted using the purposive sampling technique. Spearman rho test for bivariat analysis is used to assess the impact of functional status on the quality of life of post-stroke patients. The research instrument was a questionnaire. The Functional Status Questionnaire employs the Barthel Index scale. The respondent indicated that they were fully independent. The quality of life questionnaire employs the Short Form Stroke-Specific Quality of Life Scale (SSQOL). P-value for the spearman correlation test is 0.046 (&lt;0.05) indicates that there is a statistically significant influence between functional status and the patient's quality of life. The correlation coefficient value is r=0.368, indicating that the influence between functional status and quality of life is moderate to strong. These positive results indicate that as an individual's functional status improves, so does their quality of life one year after stroke. Consequently, the functional status of these patients can be improved through stroke rehabilitation, which is designed to enhance quality of life.</em></p><p><em> </em></p></td></tr></tbody></table></div><p><strong><em>Keywords: Functional Status, Stroke, Quality of Life</em></strong></p>
Analisa Kebutuhan Daya Listrik Terpasang Pada Perusahaan Perumda Air Minum Kabupaten Lamongan
Authors: Warno Bambang Irwanto , Laksono Arief Budi 
Published: December 2024

PDAM Lamongan is a regional company that provides clean water to serve comsumers/customers. This research is analyzing the electrical power needs of this company. Researchers used literature study methods and field observation. The data sources needed are data collection through interviews and direct observation. This analysis uses the KWH method. The results obtained are used as material for analysis using the SEC (Specific Energy Consumption) theory, so that it can show the condition/efficiency of this company. Research results of the electricity source from a PLN transformer of 240 KVA. The main panel MCCB of 350 A is divided into 5 groups, namely group 1-5 using submersible and group 5 adds AC load and 2 lighting lamps. The total load power is 84.831 Watts. The total power requirement for one month is 61.026 KWH and the monthly rupiah cost is Rp.68.478.009,48. The results of the SEC (Specific Energy Consumption) calculation which is 0,098 KWH/ are concluded to be in the criteria for average efficiency because the results are below 0,4 KWH/ according to the JICA Ministry’s efficiency book standard which is 0,4 KWH/.
Optimization Of The Role Of Village-Owned Enterprise (BUMDES) In Developing Tourism Communication Strategies Based On Social Media
Authors: Perdana Inco Hary , Winarto Intan Permata Dewi 
Published: December 2024

This research explores the potential of Village-Owned Enterprises (BUMDes) in developing tourism communication strategies, with a case study on the Tumpeng Menoreh tourist destination in Kulon Progo Regency. It employs a post-positivist approach with qualitative methodology, involving semi-structured interviews, social media platform observations, and document analysis. Rhetorical communication strategies and SWOT analysis are used to evaluate the effectiveness of social media in promoting tourism. The findings indicate that BUMDes has leveraged Instagram to enhance the visibility and accessibility of Tumpeng Menoreh through engaging visual content and narratives based on local culture. This strategy has successfully attracted visitors and empowered the local community, although challenges related to accessibility and reliance on influencers remain. The study concludes by emphasizing the importance of more structured strategic planning and diversification of social media platforms to achieve sustainable tourism.
Keywords: BUMDes, tourism communication, social media, Tumpeng Menoreh, Instagram
Quo Vadis Revision of the Broadcasting Law
Authors: Yusanto Yoki , Sjuchro Dian Wardiana , Amdan Nana Sutisna , Ramadhan Aditya , - Muhaemin 
Published: December 2024

Law of the Republic of Indonesia Number 32 Year 2002 on Broadcasting was born after the political struggle in Indonesia. It gave birth to the Indonesian Broadcasting Commission (KPI) to equalize the ownership of radio and television, thus creating a diversity of content. But now KPI's authority is weaker after the House of Representatives passed the UU Cipta Kerja. KPI's role is only like an NGO. Now the Broadcasting Law will be revised by the House of Representatives. The Program is in the form of broadcast content, who supervises it, what is the role of KPI after the Undang-undang Cipta Kerja. Instead of being an independent institution, KPI now seems to be a broadcasting Non-Governmental Organization (NGO). This research uses a qualitative method. The research was conducted by interviewing KPI commissioners in various regions in Indonesia. The authority of the Indonesian Broadcasting Commission (KPI) as an independent body must remain firm and robust, standing as the leading regulator for broadcasting institutions, both radio and television, as well as for digital media content. For social justice in Indonesia, media ownership diversity must be regulated in the revised Broadcasting Law. Ensuring media ownership diversity across various regions and sectors is essential to prevent media ownership monopolies, which could result in only a few entities controlling television and radio broadcasting.
Anastomotic iliac artery aneurysms: A delayed but dangerous complication
Authors: Levi N. , Schroeder T.V. 
Published: December 2024

Purpose: The aim of this study was to assess our experience with anastomotic iliac artery aneurysms and to assess the blood transfusion requirement in patients undergoing surgery for iliac artery aneurysms. Materials and methods: The case records of 6 patients who underwent 6 arterial reconstructive procedures for anastomotic iliac aneurysms from January 1989 to December 1995 were identified in our prospective vascular database and reviewed. Result: Five patients presented with a painful abdominal mass and one patient was asymptomatic. The average delay between the original operation and the development of the anastomotic aneurysms was 14 years. Aneurysmorrhaphy with graft interposition was the most common procedure. The one week perioperative mortality was two out of six. Out of 6 patients, 6 patients (100%) were transfused with a total of 51 units (average 8 units per operation, range from 6 to 12 units). The average measured intraoperative blood loss was 3400 ml (2000 to 5300 ml). The average pre‐operative haemoglobin was 7.8 mmol/l (range 6.6 to 9.1 mmol/l). The average post‐operative haemoglobin was 6.5 mmol/l (range 5.5 to 7.1 mmol/l). Conclusions: Anastomtic iliac aneurysm is a late but dangerous condition with a high perioperative mortality. Large volumes of blood should be avaible.
Psychostimulants in the treatment of children diagnosed with ADHD: Risks and mechanism of action
Authors: Breggin Peter R. 
Published: December 2024

Millions of children in North America are diagnosed with attention deficit/hyperactivity disorder and treated with psychostimulants such as methylphenidate, dextroamphetamine, and methamphetamine. These drugs produce a continuum of central nervous system toxicity that begins with increased energy, hyperalertness, and overfocusing on rote activities. It progresses toward obsessive/compulsive or perseverative activities, insomnia, agitation, hypomania, mania, and sometimes seizures. They also commonly result in apathy, social withdrawal, emotional depression, and docility. Psychostimulants also cause physical withdrawal, including rebound and dependence. They inhibit growth, and produce various cerebral dysfunctions, some of which can become irreversible. The “therapeutic” effects of stimulants are a direct expression of their toxicity. Animal and human research indicates that these drugs often suppress spontaneous and social behaviors while promoting obsessive/compulsive behaviors. These adverse drug effects make the psychostimulants seemingly useful for controlling the behavior of children, especially in highly structured environments that do not attend to their genuine needs.
Safety issues in Indian traditional medicine
Authors: Bhatt H.A. , Gogtay N.J. , Dalvi S.S. , Kshirsagar N.A. 
Published: December 2024

A medical system is called traditional, among others, when it is practiced within the country of its origin. The increasing use of Traditional Medicine (TM) worldwide and the growth of the related pharmaceutical industry has led to an activation of research regarding its quality, efficacy and safety. The Ayurveda and Siddha systems of traditional medicine have their origin in India. Of these, Ayurveda is one of the oldest systems of medicine in the world and the most commonly practiced form of traditional medicine in India. Subjects to be discussed comprise of issues related to herb–drug interactions, misuse of TM, variations in the action of a drug due to natural and deliberated reasons and the documentation of adverse drug reaction. Combined efforts, without any bias, by scholars from both traditional and modern medicine to optimize the risk benefit profile and to serve as guards for optimal use of TM, is the prerequisite for global harmonization.
Detecting medication errors in pharmacovigilance database: Capacities and limits
Authors: Alj L. , Touzani M.D.W. , Benkirane R. , Edwards I.R. , Soulaymani R. 
Published: December 2024

Background: Following the Institute of Medicine report on medication errors, pharmacovigilance activity is focusing more on patient safety. The aim of this study is to assess the ability to collect and identify Medication Errors “ME” from Adverse Drug Events “ADRs” reported to Pharmacovigilance Centre of Morocco. Methods: It is a retrospective analysis of ADEs reported to Pharmacovigilance Centre of Morocco from 2003 to 2006. Results: 1300 cases of ADEs were reported to the Moroccan Pharmacovigilance Centre of which 14.4% (n=187) were considered as preventable. ME associated with preventable ADEs “pADEs” and related to the medication use system, occurred most often at the stage of prescribing (36.3%), and administration (34.8%). Regarding the type of ME, most of them were related to dose errors (49.3%) following by therapeutic and clinic monitoring errors (15.9%). Among the pADEs, 41.7% were serious and the outcome was favourable in 93%. Conclusion: Mutual cooperation between various source organizations is key for detecting ME and building an extensive database. The database will helps identify situations that are most prone to errors, and hence define preventive strategies. Thus, the quality of health care delivery is more likely to improve, thereby ensuring patient safety.
Fatigue in Parkinson’s disease and potential interventions
Authors: Lou Jau-Shin 
Published: December 2024

BACKGROUND: Fatigue is common in patients with Parkinson’s disease (PD). It occurs at every stage of PD and affects quality of life. Fatigue severity worsens over time as PD progresses, and it is associated with other non-motor symptoms such as apathy, depression, sleep disorder, and cognitive dysfunction. PURPOSE: In this literature review, I discuss the measurement and pathophysiology of fatigue and fatigability. There are no evidence-based treatments for fatigue and fatigability available. I review several pilot studies on the effects of pharmacological agents and exercise on fatigue and fatigability. These studies provide some insights on the design of future larger clinical trials. CONCLUSION: Fatigue inventories including The Fatigue Severity Scale, the Multidimensional Fatigue Inventory, or theParkinson Fatigue Scale are used to assess the severity of fatigue. Finger tapping and force generation are useful in quantifying physical fatigability. A reaction time paradigm such as the Attention Network Test can be used to measure cognitive fatigability. Physical fatigability is associated with the change in cortical excitability in PD measured by Transcranial Magnetic Stimulation. Cognitive fatigability is most likely associated with the neurotransmitter abnormalities (dopaminergic, cholinergic and noradrenergic) in PD. Levodopa, modafanil, methylphenidate, and rasagiline may be effective in treating fatigue and fatigability. Exercise programs may also be effective.
Accelerating Vision Diffusion Transformers with Skip Branches
Authors: Chen Guanjie , Zhao Xinyu 
Published: December 2024

Diffusion Transformers (DiT), an emerging image and video generation model architecture, has demonstrated great potential because of its high generation quality and scalability. Despite the impressive performance, its practical deployment is constrained by computational complexity and redundancy in the sequential denoising process. While feature caching across timesteps has proven effective in accelerating diffusion models, its application to DiT is limited by fundamental architectural differences from U-Net-based approaches. Through empirical analysis of DiT feature dynamics, we identify that significant feature variation between DiT blocks presents a key challenge for feature reusability. To address this, we convert standard DiT into Skip-DiT with skip branches to enhance feature smoothness. Further, we introduce Skip-Cache which utilizes the skip branches to cache DiT features across timesteps at the inference time. We validated the effectiveness of our proposal on different DiT backbones for video and image generation, showcasing skip branches to help preserve generation quality and achieve higher speedup. Experimental results indicate that Skip-DiT achieves a \(1.5 \times\) speedup almost for free and a \(2.2 \times\) speedup with only a minor reduction in quantitative metrics. Code is available at https://github.com/OpenSparseLLMs/Skip-DiT.git.
Fast Dissolving Tablets: A Comprehensive Overview of Formulation and Manufacturing
Authors: Mangal Ritu , Bansal Mayank , . Vikas 
Published: December 2024

Despite a number of drawbacks, the oral drug delivery system is still the recommended method of medication delivery since it is easier to administer and improves patient compliance. By creating "fast dissolving tablets" (FDTs), which dissolve or disintegrate quickly without water in the mouth in a matter of seconds because of the action of a superdisintegrants or by optimising the pore structure in the formulation. Fast Dissolving Tablets (FDTs) represent an innovative drug delivery system. This article provides a comprehensive review of FDTs, covering different components used in the formulation, manufacturing technologies along with their advantages, limitations and clinical applications.
Key words: fast dissolving tablets, superdisintegrants, oral drug delivery system, manufacturing technologies.
Tantangan dan Strategi Pencegahan Konflik akibat Intoleransi dan Radikalisme di Era Digital untuk Mewujudkan Keamanan Nasional
Authors: Setiawan Budi , Setiawan Bayu , Hidayat Eri R , Widodo Pujo , Risma Saragih Herlina Juni , Sukendro Achmed 
Published: December 2024

The internet and social media have become effective platforms for spreading extremist ideologies, strengthening polarization, and creating “echo chambers” that reinforce radicalism. This research aims to identify the main challenges and formulate strategies to prevent conflicts triggered by intolerance and radicalism in the digital era. Using a qualitative approach with a case study method, this research analyzes secondary data from official documents, previous scientific studies, and social media content to understand the patterns of spreading intolerance and radicalism. The results show that the main challenges in conflict prevention include anonymity and accessibility of technology, social media algorithms that support confirmation bias, lack of digital literacy, weak supervision and regulation, and the appeal of radical ideologies. Therefore, a prevention strategy that involves strengthening digital literacy, improving regulations, and collaboration between stakeholders is considered very important in tackling radicalism in cyberspace. Hopefully, the implementation of this comprehensive strategy can realize a more resilient, inclusive and safe society from the influence of radical ideologies in the digital era. This research implies the need for multi-stakeholder collaboration in developing more effective policies to prevent radicalism in the digital era.Internet dan media sosial menjadi sarana efektif bagi penyebaran ideologi ekstrem, memperkuat polarisasi, dan menciptakan "echo chambers" yang memupuk radikalisme. Penelitian ini bertujuan untuk mengidentifikasi tantangan utama dan merumuskan strategi pencegahan konflik akibat intoleransi dan radikalisme di era digital demi mewujudkan keamanan nasional. Menggunakan pendekatan kualitatif dengan metode studi kasus, penelitian ini menganalisis data sekunder dari dokumen resmi dan penelitian terdahulu, serta konten media sosial untuk memahami pola penyebaran intoleransi dan radikalisme. Hasil penelitian menunjukkan bahwa anonimitas dan aksesibilitas teknologi, algoritma media sosial yang memperkuat bias konfirmasi, kurangnya literasi digital, pengawasan dan regulasi yang lemah, serta daya tarik ideologi radikal merupakan tantangan utama dalam mencegah konflik akibat intoleransi dan radikalisme di era digital. Oleh karena itu, penguatan regulasi dan literasi digital serta kolaborasi multi-stakeholder dapat menjadi strategi dalam mengurangi radikalisme di dunia maya. Dengan strategi yang komprehensif ini, diharapkan tercipta masyarakat yang lebih tangguh, inklusif, dan aman dari pengaruh ideologi radikal di era digital. Penelitian lebih lanjut diperlukan untuk mengevaluasi efektivitas program literasi digital, dan menganalisis dampak regulasi konten media sosial. Penelitian ini mengimplikasikan perlunya kolaborasi multi-stakeholder dalam menyusun kebijakan yang lebih efektif untuk mencegah radikalisme di era digital
Triglyceride-glucose index mediates the association between residual cholesterol and stroke among middle-aged and older adults in China: a prospective, nationwide, population-based study
Authors: Li Xu , Hu Jia-Guang , Liao Qian , Wu Ying , Huo Rong-Rui 
Published: December 2024

BackgroundBoth triglyceride-glucose (TyG) index and residual cholesterol (RC) are predictors of stroke; however, to what extent the RC is associated with stroke through TyG index is unclear. This study examined whether the TyG index mediates the association of RC with incident stroke and the extent of interaction or joint relations of RC and TyG index with stroke in middle-aged and older Chinese adults.MethodsThis is an ongoing prospective cohort study initiated in 2011 that included 10,569 middle-aged and older Chinese adults without stroke at baseline. The exposure was RC, the mediator was TyG index, and the outcome was stroke which followed up from June, 2011, to June, 2018. Mediation analysis was used to explore whether the TyG index mediated the association between RC and stroke risk.ResultsOf the 10,569 participants, 4,978 (47.1%) were men; the mean (SD) age was 59.01 (9.43) years. During a median follow-up of 7.1 years, 734 (7.0%) participants experienced a stroke. In the adjusted Cox models, A one SD increase in RC was associated with an elevated risk of stroke (HR, 1.09; 95% CI, 1.02–1.16), as well as TyG index (HR, 1.14; 95% CI, 1.06–1.23). No significant multiplicative or additive interactions were found between the TyG index and RC on stroke risk (HR for multiplicative: 1.07, 95% CI, 0.67–1.70; Synergy index: 1.05, 95% CI, 0.16–6.88). TyG index mediated the association between RC and stroke (b, −0.16; 95% CI, −0.30 to −0.03). Subgroup analyses and sensitivity analyses showed consistent results.ConclusionsThis study evidence that the TyG index completely mediates the association between RC and stroke risk among middle-aged and older Chinese adults. These findings highlight the importance of considering RC and the TyG index in stroke risk assessment.