bluuebunny/crossref_metadata_2025_split huggingface dataset:
O “eco” do marxismo: o metabolismo social do capital e o pensamento ambiental | The “echo” of Marxism: the social metabolism of capital and environmental thinking
Authors: Silva Luiz Felipe Barros 
Published: January 2019

As teorias de Karl Marx e Friedrich Engels reverberaram nos diversos campos da ciência, dando margem a variadas interpretações de seus pensamentos, muitas delas apressadas em taxá-los de economicistas ou deterministas antinatureza. No pensamento ecológico e ambiental, estas interpretações ainda possuem muitos seguidores; por isso, o presente artigo vem trazer uma interpretação diferente do pensamento marxista ancorado sobretudo em Guillermo Foladori e John Bellamy Foster, que não antepõem o legado de Marx e Engels à luta pela defesa da natureza. Pelo contrário, esses autores entendem que Marx e Engels revelaram ao mundo os constituintes internos do metabolismo social do capital, o modo de produção mais avassalador para com a natureza já existente, e, assim, são perfeitamente compatíveis como mediação teórica para a superação deste sistema social que vem colocando a sobrevivência humana em risco quanto mais reproduz seus antagonismos.Palavras-Chave: Marx e a ecologia; natureza em Marx; capital e meio ambiente; marxismo; ambientalismo. Abstract – The theories of Karl Marx and Friedrich Engels reverberated in diverse fields, giving margin to different readings. Many hurried to label them as economicists and anti-nature determinists. In ecological and environmental thinking, these interpretations still have many followers; therefore, this article brings a different interpretation of Marxist thought anchored mainly in Guillermo Foladori and John Bellamy Foster, who do not pit the legacy of Marx and Engels against the defense of nature. Instead, they understand Marx and Engels revealed to the world the internal constituents of the social metabolism of capital, the production mode that is most overwhelming for nature, and so they are perfectly compatible as a theoretical mediation to overcome this social system that is putting human survival at risk as it reproduces its antagonisms.Keywords: Marx and ecology; nature in Marx; capital and environment; Marxism; ambientalism.
The Role Of Purse String Closure As The Primary Treatment Of Hemangioma
Authors: Wardhana Aditya , Atmaja Tessa M. 
Published: January 2019

Hemangioma is a common congenital disorder which happens in neonates or infant, with predilection sites in the face and neck. Not every case of hemangioma requires a surgical treatment. Some will regress spontaneously. In some cases which requires resection, the aesthetic aspects of the repair must be considered as the sites of the lesion involved the face and neck areas, which is greatly exposed.Two patients with hemangioma of the left cheek were admitted to Plastic Surgery Department of Cipto Mangunkusumo Hospital. The patients underwent excision and primary closure with purse string technique. Patients were evaluated at one week after surgery and a month after to assess scar appearance. Follow up evaluation revealed less visible scar compared to the immediate result. A well-known technique used by many plastic surgeons is the circular incision followed by purse-string closure. The use of this technique was known to produce less visible scar. Hemangiomas acts as a tissue expander, which make it applicable to close the defect using purse string closure.
Innervated Bilobed Radial Forearm Free Flap For Tongue Reconstruction
Authors: Atmodiwirjo Parintosa , Bangun Kristaninta , Handayani Siti , Djamaloeddin Chaula , Nindita Eliza 
Published: January 2019

Hemiglossectomy defects need reconstructions to restore normal functions and aesthetic outcomes. It is therefore prudent that well-planned reconstructive technique is needed for a good functional substitution for the defect.This case report describes a 30 years old male who developed T2N1M0 squamous cell carcinoma of the left tongue. The patient underwent a tongue reconstruction following his hemiglossectomy involving floor of the mouth without mandibular resection.The optimum method of reconstructing a major defect such as hemiglossectomy with floor of the mouth resection is best carried out by using microvascular free tissue transfer. We conclude that the radial forearm free flap is good method for reconstructing major defects of the tongue. The radial forearm free flap is thin, can be raised without patient position change, has constant vascular anatomy, and provides an advantage in the aesthetic aspect at the donor site.
The Advantages of Vascularized Fibular Bone Graft For Mandibular Tumor Reconstruction
Authors: Atmodiwirjo Parintosa , Putri Nandita Melati 
Published: January 2019

Mandibular reconstruction are often indicated in patient who underwent ablation or excision of the mandible due to malignancy of the oral cavity.In this paper we will discuss about the mandibular reconstruction with use of alloplastic implant, and vascularized bone graft. Four cases of oral cavity tumor which were referred to the plastic surgery division at Cipto Mangunkusumo hospital during 2005-2011, after being diagnosed with oral cavity tumor were re-viewed. Mandibular reconstruction can be done using alloplastic implant, non-vascularized bone graft or vascularized bone graft. In this paper we studied four patients who needed mandibular reconstruction after ablation of oral cavity tumors. Patients who underwent reconstruction with alloplastic implants all had complications such as broken hardware. Where as in patient who underwent free fibular tissue transfer there were no complications at all. We can conclude that in less vascularized surrounding tissue as in cases that received or will receive other treatment such as chemotherapy or radiation that vascularized bone graft are superior. The bone healing in vascularized bone graft also does not depend on creeping substitution like in non vascularized bone graft.
Accounting and its Relationship to General Equilibrium Theory
Authors: Shubik Martin 
Published: January 2019

Abstract
Accounting both for macro and microeconomic purposes deals with process and dynamics. Much of the best microeconomic theory has dealt only with statics. General equilibrium theory shows the virtues of a price system, but abstracts from price formation and all of the accounting problems which appear in disequilibrium. An approach is suggested here for reconciliation of accounting with general equilibrium. More generally, it is suggested that the importance of accounting to economic theory has been underestimated.
Postmeal Optogenetic Inhibition of Dorsal or Ventral Hippocampal Pyramidal Neurons Increases Future Intake
Authors: Hannapel Reilly , Ramesh Janavi , Ross Amy , LaLumiere Ryan T. , Roseberry Aaron G. , Parent Marise B. 
Published: January 2019

AbstractMemory of a recently eaten meal can serve as a powerful mechanism for controlling future eating behavior because it provides a record of intake that likely outlasts most physiological signals generated by the meal. In support, impairing the encoding of a meal in humans increases the amount ingested at the next eating episode. However, the brain regions that mediate the inhibitory effects of memory on future intake are unknown. In the present study, we tested the hypothesis that dorsal hippocampal (dHC) and ventral hippocampal (vHC) glutamatergic pyramidal neurons play a critical role in the inhibition of energy intake during the postprandial period by optogenetically inhibiting these neurons at specific times relative to a meal. Male Sprague Dawley rats were given viral vectors containing CaMKIIα-eArchT3.0-eYFP or CaMKIIα-GFP and fiber optic probes into dHC of one hemisphere and vHC of the other. Compared to intake on a day in which illumination was not given, inhibition of dHC or vHC glutamatergic neurons after the end of a chow, sucrose, or saccharin meal accelerated the onset of the next meal and increased the amount consumed during that next meal when the neurons were no longer inhibited. Inhibition given during a meal did not affect the amount consumed during that meal or the next one but did hasten meal initiation. These data show that dHC and vHC glutamatergic neuronal activity during the postprandial period is critical for limiting subsequent ingestion and suggest that these neurons inhibit future intake by consolidating the memory of the preceding meal.
José Benjamín Bernal Suárez: Derecho humano a la familia. Retos y alcances en el siglo XXI, UAEM y GEDISA editorial, México, 2017, 174 páginas.
Authors: Bernal Ballesteros María Jose 
Published: January 2019

El derecho a la familia suele ser abordado desde la rama del derecho privado, es decir todo lo concerniente al estado de las personas. No obstante, la novedad que presenta el libro Derecho Humano a la familia. Retos y alcances en el siglo XXI es que a diferencia de lo anterior, aborda el tema del derecho a la familia desde la óptica de los derechos humanos.La primera justificación que hace el autor para sostener esta teoría se basa en la naturaleza jurídica y en la esencia misma de la familia, desde esta perspectiva entiende que “al ser una instrucción natural, la familia existe por la propia naturaleza del hombre” y que en este sentido “negar este derecho es como negarle al hombre el carácter de persona, el dominio sobre su propio ser”.En consecuencia de lo anterior y desde una postura iusnaturalista, el autor retoma la conceptualización de los derechos humanos y su relación con la dignidad para reafirmar su propuesta.
Whole-Genome Multi-omic Study of Survival in Patients with Glioblastoma Multiforme
Authors: Bernal Rubio Yeni L , González-Reymúndez Agustin , Wu Kuan-Han H , Griguer Corinne E , Steibel Juan P , de los Campos Gustavo , Doseff Andrea , Gallo Kathleen , Vazquez Ana I 
Published: January 2019

AbstractGlioblastoma multiforme (GBM) has been recognized as the most lethal type of malignant brain tumor. Despite efforts of the medical and research community, patients’ survival remains extremely low. Multi-omic profiles (including DNA sequence, methylation and gene expression) provide rich information about the tumor. These profiles are likely to reveal processes that may be predictive of patient survival. However, the integration of multi-omic profiles, which are high dimensional and heterogeneous in nature, poses great challenges. The goal of this work was to develop models for prediction of survival of GBM patients that can integrate clinical information and multi-omic profiles, using multi-layered Bayesian regressions. We apply the methodology to data from GBM patients from The Cancer Genome Atlas (TCGA, n = 501) to evaluate whether integrating multi-omic profiles (SNP-genotypes, methylation, copy number variants and gene expression) with clinical information (demographics as well as treatments) leads to an improved ability to predict patient survival. The proposed Bayesian models were used to estimate the proportion of variance explained by clinical covariates and omics and to evaluate prediction accuracy in cross validation (using the area under the Receiver Operating Characteristic curve, AUC). Among clinical and demographic covariates, age (AUC = 0.664) and the use of temozolomide (AUC = 0.606) were the most predictive of survival. Among omics, methylation (AUC = 0.623) and gene expression (AUC = 0.593) were more predictive than either SNP (AUC = 0.539) or CNV (AUC = 0.547). While there was a clear association between age and methylation, the integration of age, the use of temozolomide, and either gene expression or methylation led to a substantial increase in AUC in cross-validaton (AUC = 0.718). Finally, among the genes whose methylation was higher in aging brains, we observed a higher enrichment of these genes being also differentially methylated in cancer.
Combinatorial Genetic Control of Rpd3S Through Histone H3K4 and H3K36 Methylation in Budding Yeast
Authors: Lee Kwan Yin , Ranger Mathieu , Meneghini Marc D 
Published: January 2019

Abstract
Much of euchromatin regulation occurs through reversible methylation of histone H3 lysine-4 and lysine-36 (H3K4me and H3K36me). Using the budding yeast Saccharomyces cerevisiae, we previously found that levels of H3K4me modulated temperature sensitive alleles of the transcriptional elongation complex Spt6-Spn1 through an unknown H3K4me effector pathway. Here we identify the Rpd3S histone deacetylase complex as the H3K4me effector underlying these Spt6-Spn1 genetic interactions. Exploiting these Spt6-Spn1 genetic interactions, we show that H3K4me and H3K36me collaboratively impact Rpd3S function in an opposing manner. H3K36me is deposited by the histone methyltransferase Set2 and is known to promote Rpd3S function at RNA PolII transcribed open reading frames. Using genetic epistasis experiments, we find that mutations perturbing the Set2-H3K36me-Rpd3S pathway suppress the growth defects caused by temperature sensitive alleles of SPT6 and SPN1, illuminating that this pathway antagonizes Spt6-Spn1. Using these sensitive genetic assays, we also identify a role for H3K4me in antagonizing Rpd3S that functions through the Rpd3S subunit Rco1, which is known to bind H3 N-terminal tails in a manner that is prevented by H3K4me. Further genetic experiments reveal that the H3K4 and H3K36 demethylases JHD2 and RPH1 mediate this combinatorial control of Rpd3S. Finally, our studies also show that the Rpd3L complex, which acts at promoter-proximal regions of PolII transcribed genes, counters Rpd3S for genetic modulation of Spt6-Spn1, and that these two Rpd3 complexes balance the activities of each other. Our findings present the first evidence that H3K4me and H3K36me act combinatorially to control Rpd3S.
Teodoro Lepnerio apybraižos „Prūsų lietuvis“ citatos Simono Daukanto veikale „Būdas senovės lietuvių, kalnėnų ir žemaičių“
Authors: Bončkutė Roma 
Published: January 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]
Straipsnyje analizuojamos Teodoro Lepnerio (Theodorus Lepner, 1633–1691) etnografinės apybraižos „Der Preuſche Littauer“ (1744; „Prūsų lietuvis“) citatos ir nuorodos Simono Daukanto veikale „BUDĄ Senowęs–Lëtuwiû Kalnienû ir Ƶámajtiû“ („Būdas senovės lietuvių, kalnėnų ir žemaičių“). Tiriama S. Daukanto pažinties su „Prūsų lietuvio“ tekstu raida. Aptariamas Lietuvių literatūros ir tautosakos institute saugomas S. Daukanto rankraštis „Marguminai“ ir jame esančios T. Lepnerio knygos citatos, t. y. citatų išrašų istorija, datavimas, turinys. Nagrinėjamas istoriko darbo su šaltiniais pobūdis. Straipsnyje analizuojama 31 nuoroda, citavimo ypatumai ir citatų turinys. Manoma, kad S. Daukantas, turėdamas remtis veikalu, kur Prūsijos kunigaikštystės lietuvis pavaizduotas kaip marginalios mažumos atstovas, keistas sarkazmo vertas objektas, a priori pasirinko faktų reinterpretacijos kelią. Iš subjekto pozicijos ėmęsis aprašyti lietuvių būdą, praeitį, S. Daukantas atliko šaltinio istorinį revizionizmą. T. Lepnerio teksto revizionizmas lėmė citavimo pobūdį: vyrauja parafrazės, laisvas autoriaus minčių persakymas, šaltinio duomenų koreliacijos ir priežastingumo keitimas. Išvadose apibendrinamos S. Daukanto veikale esančios sąsajos su T. Lepnerio tekstu. Nustatyta, kad S. Daukantas gana tiksliai pakartoja šaltinio tekstą ir pateikia tikslią nuorodą 17 kartų. 8 kartus istorikas nurodo klaidingai: nei turinio, nei puslapių požiūriu nėra atitikimo. 6 nuorodų turinys yra imtas iš šaltinio, bet netiksliai pateikti skyrių ir puslapių numeriai.
Vokietijos metraščiui „Annaberger Annalen über Litauen und deutsch-litauische Beziehungen“ – ketvirtis amžiaus
Authors: Hermann Arthur 
Published: January 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]
Tyrimo objektas yra Vokietijoje nuo 1993 m. leidžiamas metraštis „Annaberger Annalen über Litauen und deutsch-litauische Beziehungen“ („Anabergo analai apie Lietuvą bei vokiečių ir lietuvių santykius“). Per 25 metus tradiciniu ir skaitmeniniu būdu paskelbti 26 tomai, kuriuos sudaro 221 autoriaus pateiktų 318 straipsnių, apimančių 7440 puslapių. Rengia ir leidžia iniciatorių grupė Arthur Hermann, Annemarie Lepa, dr. Christina Nikolajew ir dr. Lina Pilypaitytė. Užsakovai yra Baltischer Christlicher Bund (Bonn) ir Litauisches Kulturinstitut (Lampertheim). Nusistovėjo tradicija moksliniams straipsniams kiekviename tome skirti du trečdalius puslapių, trečdalį – kitokio pobūdžio publikacijoms. Tyrimų nuolat gausėja. Anksčiau plačiau tyrinėti Vokiečių Ordino ir Lietuvos Didžiosios Kunigaikštystės santykiai, šiandien daugiau rašoma XIX–XX a. Vokietijos ir Lietuvos ryšių bei kitomis temomis, Rytų Prūsijos, Klaipėdos krašto gyventojų ir paveldo klausimais. Metraščio spausdintinės versijos abonentų yra apie 100, skaitmeninės – tūkstančiai. Metraščio ateitis nėra aiški dėl finansavimo problemų.
Aktualitások a sérült immunitású betegek cytomegalovirusinfekcióinak ellátásában. I. Epidemiológia és klinikai szempontok
Authors: Sinkó János 
Published: January 2019

Abstract: Human cytomegalovirus is a DNA virus with a global prevalence of 40–100%. In humans, primary infection is followed by a lifelong latent persistent phase. Even in individuals developing adequate specific immunity, interactions with the resident virus do probably occur. Clinically significant problems, however, appear primarily in immunocompromised hosts. As a result of an impaired T-cell mediated immunity, viral reactivation as well as a viral disease resulting in organ damage can develop. Most severely affected are HIV positive persons in AIDS stage and individuals undergoing solid organ or stem cell transplantation. As vital functions and survival may adversely be affected by cytomegalovirus reactivation and disease, it is of paramount significance to evaluate evident risk factors. Viral reactivation and organ specific disease can be detected by several methods based on conventional and molecular biological and histological diagnostic techniques. An up-to-date management of affected patient groups requires a meticulous assessment of the possible risk for cytomegalovirus infection and development of an adequate antiviral strategy. Orv Hetil. 2019; 160(3): 83–92.
SALURAN PEMASARAN RUMPUT LAUT (Eucheuma cottonii) DI SUMBA TIMUR, NUSA TENGGARA TIMUR
Authors: Soejarwo Permana Ari , Yusuf Risna 
Published: January 2019

ABSTRAKNusa Tenggara Timur merupakan produsen terbesar kedua setelah Sulawesi Selatan dalam produksi rumput laut jenis Eucheuma cottonii. Karena itu, peluang pengembangan rumput laut jenis E. cottonii sangat menjanjikan dengan pangsa pasar yang cukup tinggi. Penelitian ini bertujuan untuk mengetahui saluran pemasaran rumput laut jenis Eucheuma cottonii di Sumba Timur Provinsi Nusa Tenggara Timur. Data dan informasi dikumpulkan melalui observasi lapangan dan wawancara mendalam dengan pembudidaya serta dengan pengumpulan data sekunder. Data dianalisis secara kualitatif serta diuraikan dalam bentuk deskriptif dengan memberikan informasi mengenai saluran pemasaran rumput laut jenis Eucheuma cottonii di Sumba Timur. Hasil penelitian menunjukkan bahwa saluran pemasaran rumput laut di Sumba Timur dapat ditentukan oleh sumber permodalan yang berasal dari modal pribadi dan koperasi sehingga pemasaran tidak dipengaruhi oleh pedagang atau tengkulak. Kemudian dari sisi serapan dan pemasaran sumput laut dapat ditentukan oleh jenis produksi rumput laut yang terdiri dari raw material dan chips rumput laut. Raw material akan diserap oleh pedagang rumput laut lokal, pedagang rumput laut luar daerah Sumba Timur dan PT ASTIL. PT ASTIL akan mengolah rumput laut menjadi chips yang kemudian diserap oleh pembeli yang ada di Maassar, Surabaya dan Jakarta.Title: ABSTRACTEast Nusa Tenggara is the second largest producer after South Sulawesi in the production of Eucheuma cottonii. Therefore, the opportunity to develop Euchema cottonii seaweed is very promising with a high market share. This study aims to determine the marketing distribution of Eucheuma cottonii in East Sumba, East Nusa Tenggara Province. Data and information were collected through field observations and in-depth interviews with farmers as well as with secondary data collection. The data were analyzed qualitatively and described in descriptive form by providing information about the marketing distribution of Eucheuma cottonii in East Sumba. The results showed that the marketing distribution for seaweed in East Sumba could be determined by capital sources that originating from private capital and cooperatives so that marketing was not influenced by traders or middlemen. Furthermore the absorption and marketing of seaweed can be determined by the type of seaweed production consisting of raw material and seaweed chips. Raw material will be absorbed by local seaweed traders, seaweed traders in outside East Sumba and PT ASTIL. PT ASTIL will process seaweed into chips which are then absorbed by buyers in Makassar, Surabaya and Jakarta.
Exosomal proteases in colorectal cancer
Authors: Zambalova E. A. , Patysheva M. R. , Dimcha A. A. , Tamkovich S. N. , Grigor’eva A. E. , Kolegova E. S. , Kondakova I. V. , Afanas’ev S. G. , Yunusova N. V. 
Published: January 2019

The objectiveis to evaluate the level of ADAM10 and ADAM17 (a disintegrin and metalloproteinase) proteases, as well as 20S-proteasomes in blood plasma exosomes of patients with colorectal cancer.Materials and methods. The study included 60 patients with colorectal cancer (T2–4N0–2M0–1) and 10 control patients. The material for the study was EDTA blood plasma. Exosomes of blood plasma were isolated by ultrafiltration with ultracentrifugation. The level of tetraspanin-associated (ADAM10 and ADAM17) and tetraspanin-non-associated (20S-proteasome) proteases was evaluated by flow cytometry and Western blotting.Results.A twice negative subpopulation (ADAM10–/ADAM17–) predominated in blood plasma exosomes of colorectal cancer patients and control patients. The level of ADAM10+/ADAM17– exosomes was significantly higher in the exosomes of the plasma of control patients. There were no significant differences between the ADAM10/ADAM17 subpopulations and the 20S-proteasome level, depending on sex, age and tumor grade. A decrease in the ADAM10+/ADAM17– subpopulation was found in patients with metastatic colorectal cancer with hematogenous metastases compared with patients with T2–4N1–2M0 and 20S-proteasome compared to T2–4N0M0. A decrease in ADAM10–/ ADAM17+ exosomes and 20S-proteasomes level was found in exosomes of patients with colorectal cancer with a metabolic syndrome in comparison with patients without metabolic disorders.