bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Supreme laryngeal mask airway versus endotracheal intubation for airway management during general anesthesia for Cesarean section: a randomized controlled trial
Authors: Yao Wei Yu , Li Shi Yang , Yuan Yong Jin , Tan Hon Sen , Han Nian-Lin Reena , Sultana Rehena , Assam Pryseley N , Sia Alex Tiong Heng , SNG Ban Leong 
Published: February 2019

Abstract
Background: The obstetric airway is a significant cause of maternal morbidity and mortality. Endotracheal intubation is considered the standard of care but the laryngeal mask airway (LMA) has gained acceptance as a rescue airway and has been incorporated into the obstetric airway management guidelines. In this randomized controlled trial, we compared the Supreme LMA (SLMA) with endotracheal intubation (ETT) in managing the obstetric airway during Caesarean section.
Methods: Parturients who underwent elective Caesarean section under general anesthesia were randomized to receive either an SLMA or ETT as their airway device. Our primary outcome was first-attempt insertion success. Successful insertion was defined as adequate bilateral air entry with auscultation and the presence of end-tidal carbon dioxide on the capnogram. The first-attempt insertion success rate was compared using the Chi-Square test. Secondary outcomes included time-to-ventilation, seal pressure, ventilation/hemodynamic parameters, occurrence of clinical aspiration, fetal outcomes, and maternal side effects associated with the airway device.
Results: We recruited 920 parturients (460 SLMA, 460 ETT) who underwent elective Caesarean section under general anesthesia. Patient characteristics were similar between the groups. First attempt success was similar (Risk Ratio--RRETT/SLMA: 1.00 (95%CI: 0.25, 4.02), p= 1.00). SLMA was associated with reduced time to effective ventilation (Mean Difference-- MD -22.96; 95%CI: -23.71, -22.21 seconds) compared to ETT group (p<0.0001). Ventilation parameters, maternal and fetal outcomes were similar between the groups, and there was no aspiration.
Conclusions: SLMA could be an alternative airway management technique for a carefully selected low risk obstetric population, with similar insertion success rates, reduced time to ventilation and less hemodynamic changes compared with ETT. Our findings are consistent with the airway guidelines in recommending the second line use of LMA in the management of obstetric airway.
Ethics Approval: This study was approved by the Institutional Review Board (approval obtained on 25th October 2012) at the Quanzhou Women’s and Children’s Hospital, Fujian Province, China (clinical trials registration number: NCT01858467).
Keywords: Laryngeal Mask Airway, Obstetric, Cesarean Section, General Anesthesia.
Performing <i>with</i> the Masquerade: Towards a Corporeal Reconstitution of Sophie Taeuber’s Dada Performances
Authors: Stalpaert Christel , Doutreligne Sophie 
Published: February 2019

This contribution aims for a “corporeal reconstitution” (Irigaray) of Sophie Taeuber’s (1889-1943) dance performances at the Cabaret Voltaire and the Galerie Dada in 1916/17. This means that the movements from the static images informing the history of Dada art need to be re-imagined. It implies a rendering perceptible of Taeuber’s trained dancer’s body, its particular movements, and the quality of these movements. Through testimonies of contemporaries, it becomes clear that Taeuber not only dances in a costume or behind a mask but with the mask, the costume and sound poems. The reconstitution of the moving body with the mask thus points at a foregrounding of the masquerade to which she is convicted as a woman. Her mimetic strategy (Irigaray) or playful repetition of the masquerade entails a “radically new mode of relating” (Obler 2009, 223) between human and non-human materiality. Taeuber is not only moving in between puppet and puppeteer, movement and stasis, abstraction and expressivity, performer and mask, presence and absence, but also in between feminine and masculine. The hybrid movements in her mimetic strategy disrupt the binary nature of the oppositional pairs. In dancing the perpetual movement in between dualities, through a patchwork of genres and materials (her drawings, embroideries and tapestries are also driven by kinetic forces), Taeuber not only playfully rebels against patriarchal discourse, but also against the dehumanizing effects of World War One violently raging through Europe.
Memórias e apagamentos: quem decide sobre o patrimônio no contexto urbano
Authors: Moura Ana Carolina , Koehntopp Paulo Ivo 
Published: February 2019

Este artigo discute algumas decisões de preservação patrimonial adotadas pela Comissão do Patrimônio Histórico, Arqueológico, Artístico e Natural do Município de Joinville (COMPHAAN) na ocasião da demolição do conjunto arquitetônico das fábricas Mayerle Boonekamp e Linhas Corrente S.A., patrimônio fabril da cidade de Joinville (SC) que constava no cadastro de Unidades de Interesse de Preservação (UIPs). Além dos questionamentos acerca da liberação das unidades para demolição,em decorrência do pedido de uma grande rede de supermercados, outros pontos de discussão são as medidas de preservação adotadas antes da demolição, as tensões relativas à preservação do patrimônio cultural no contexto de urbanização de Joinville e os agentes que decidem sobre o direito ao patrimônio e à memória.
Synthesis and Reactivity of 6,8-Dibromo-2-ethyl-4H-benzo[d][1,3]oxazin-4-one Towards Nucleophiles and Electrophiles and Their Anticancer Activity
Authors: El-hashash Maher A. , Ali Amira T. , Hussein Rasha A. , El-Sayed Wael M. 
Published: February 2019

Background:
The genetic heterogeneity of tumor cells and the development of therapy-resistant
cancer cells in addition to the high cost necessitate the continuous development of novel targeted therapies.

Methods:
In this regard, 14 novel benzoxazinone derivatives were synthesized and examined for anticancer
activity against two human epithelial cancer cell lines; breast MCF-7 and liver HepG2 cells. 6,8-Dibromo-2-
ethyl-4H-benzo[d][1,3]oxazin-4-one was subjected to react with nitrogen nucleophiles to afford quinazolinone
derivatives and other related moieties (3-12). Benzoxazinone 2 responds to attack with oxygen nucleophile such
as ethanol to give ethyl benzoate derivative 13. The reaction of benzoxazinone 2 with carbon electrophile such
as benzaldehyde derivatives afforded benzoxazinone derivatives 14a and 14b.The structure of the prepared
compounds was confirmed with spectroscopic tools including IR, 1H-NMR, and 13C-NMR.

Results:
Derivatives 3, 9, 12, 13, and 14b exhibited high antiproliferative activity and were selective against
cancer cells showing no toxicity in normal fibroblasts. Derivative 3 with NH-CO group in quinazolinone ring
was effective only against breast cells, while derivative 12 with NH-CO group in imidazole moiety was only
effective against liver cells probably through arresting cell cycle and enabling repair mechanisms. The other
derivatives (9, 13, and 14b) had broader antiproliferative activity against both cell lines. These derivatives enhance
the expression of the p53 and caspases 9 and 3 to varying degrees in both cell lines. Derivative 14b
caused the highest induction in the investigated genes and was the only derivative to inhibit the EGFR activity.

Conclusions:
The unique features about derivative 14b could be attributed to its high lipophilicity, high carbon
content, or its extended conjugation through planar aromatic system. More investigations are required to identify
the lead compound(s) in animal models.
Alterations of RNA Metabolism by Proteomic Analysis of Breast Cancer Cells Exposed to Marycin: A New Optically Active Porphyrin
Authors: Taverna Elena , De Bortoli Maida , Maffioli Elisa , Corno Cristina , Ciusani Emilio , Trivulzio Silvio , Pinelli Arnaldo , Tedeschi Gabriella , Perego Paola , Bongarzone Italia 
Published: February 2019

Objective:
Marycin is a porphyrin-type compound synthetically modified to spontaneously
release fluorescence. This study is aimed at understanding possible mechanisms that could account for
the antiproliferative effects observed in marycin. A proteomic approach was used to identify molecular
effects. The proteome of proliferating MDA-MB-231 breast cancer cells was compared with that of
marycin-treated cells.

Methods:
Label-free proteomic analysis by liquid chromatography coupled with tandem mass spectrometry
(LC-MS/MS) was used to reveal changes in protein expression and fluorescence microscopy
and flow cytometry were used to detect subcellular organelle dysfunctions.

Results:
The bioinformatic analysis indicated an enhancement of the expression of proteins remodeling
RNA splicing and more in general, of RNA metabolism. Marycin did not localize into the mitochondria
and did not produce a dramatic increase of ROS levels in MDA-MB-231 cells. Marycin stained organelles
probably peroxisomes.

Conclusions:
The results could support the possibility that the peroxisomes are involved in cell response
to marycin.
Optimización de las condiciones de producción de cápsulas con microestacas para aumentar el tiempo de almacenamiento de la planta medicinal mexicana Castilleja tenuiflora (Orobanchaceae)
Authors: León Romero Yatzil , Trejo Espino José Luis , Salcedo-Morales Guadalupe , Trejo-Tapia Gabriela , Evangelista Lozano Silvia 
Published: February 2019

Antecedentes y Objetivos: Castilleja tenuiflora es una de las plantas mexicanas, silvestres y medicinales cultivadas in vitro que presentan actividad biológica antiinflamatoria y antiulcerogénica. La encapsulación de microestacas es una opción para propagar y prolongar el almacenamiento de esta planta. El objetivo de este estudio fue establecer un método para la encapsulación y conservación de microestacas de C. tenuiflora sin afectar el contenido de sus compuestos.Métodos: Las cápsulas fueron elaboradas con alginato de sodio en complejo con cloruro de calcio dihidratado como matriz y microestacas de tejido proveniente de plántulas cultivadas in vitro. Se probaron diferentes concentraciones y tiempos de polimerización, así como diferentes tiempos de almacenamiento y temperatura, para posteriormente analizar los metabolitos mayoritarios de los extractos metanólicos mediante cromatografía (HPLC) de las plantas resultantes.Resultados clave: La combinación para la producción de cápsulas con microestacas es alginato de sodio al 3% y cloruro de calcio dihidratado al 50 mM, con 25 minutos de polimerización. Las plántulas derivadas de semillas sintéticas, almacenadas por 100 días presentaron los mismos compuestos que las plantas donantes.Conclusiones: La encapsulación de microestacas de C. tenuiflora con alginato de sodio y cloruro de calcio dihidratado permite el almacenamiento del material vegetal y se mantienen sus compuestos principales, por lo que es una alternativa para mantener el genotipo de plantas elite y contrarrestar el saqueo de plantas silvestres.
Prediction of Length of Study of Student Applicants Using Case Based Reasoning
Authors: Aesyi Ulfi Saidata , Wardoyo Retantyo 
Published: February 2019

Graduation is important matter in college. Length of study can be used to evaluate curriculum. It affect accreditation score of the sutdy program. Based on Akreditasi Program Studi Magister Buku V Pedoman Penilaian Instrumen Akreditasi 3rd standard there is rule about students and graduation, such as profile of the graduates including average length of study time and gpa (grade point average) of graduates.In this study, system built to predict Gadjah Mada University Master of Computer Science student applicant’s length of study. It used new case with 13 features from applicant that will be predict as new case, then calculate local similarity using euclidean distance and hamming distance while global similarity using nearest neighbor. Maximum value of global similarity taken as solution while revised will be done if it’s value below threshold.Result of this study show that system can help study program to manage educational process. It show 76% accuracy of 50 data.
Much Ado about Nothing: The (Lack of) Economic Impact of Data Privacy Breaches
Authors: Richardson Vernon J. , Smith Rodney E. , Watson Marcia Weidenmier 
Published: February 2019

ABSTRACT
In this paper, we examine the consequences of data breaches for a breached company. We find the economic consequences are, on average, very small for breached companies. On average, breaches result in less than −0.3 percent cumulative abnormal returns in the short window around the breach disclosure. Except for a few catastrophic breaches, the nominal difference in cumulative abnormal returns between breach companies and the matched companies disappears within days after the breach. We also test whether data breaches affect future accounting measures of performance, audit and other fees, and future Sarbanes-Oxley Section 404 reports of material internal control weaknesses, but find no differences between breach and matched companies. Our results address the question why companies are not spending more to reduce breaches. We conclude by providing a few explanations of why there appears to be an effect at the economy-wide level, but no noticeable effect on individual company performance.
MEASURING THE STUDENTS’ PERCEPTION OF SERVICE QUALITY
Authors: Kurniawan Leonardi Lucky , . N. Purnomolastu 
Published: February 2019

Like in many other countries, higher education institutions in Indonesia are facing intense competition as the higher education market becomes globalized and competitive pressure intensifies. It is essential that higher education institutions continually monitor the quality of their services and commit themselves to continuous quality improvements in order to respond to the needs of their stakeholders. Measuring service quality in higher education is thus essential In order to provide a comprehensive view of the quality of education, it is valuable to assess not only student perceptions of their educational outcomes but also their perceptions of the manner in which polytechnic education is provided.This study aims at measuring the students’ perception of the service quality of education in a department; identifying differences of the student perception on the service quality based on their academic profiles; identifying which service attributes are more influential in providing service in higher education; and offering recommendation to the management which area(s) still need(s) some improvement.Using the 5-scale questionnaires, the researchers collected the data for the study from graduates of the 5 departments- Accounting, Marketing Management, Secretary Foreign Business Language and Taxation. Pearson Chi-Square and Alpha Cronbach techniques were used to test the validity and reliability before analyzing the data from the questionnaire. Descriptive statistics was deployed to find out the mean value of each indicator. This was followed bv Dummy Regression analysis. JThe findings of the study suggest that faculty plays the most prominent indicator in reflecting the students perception of service quality of department.
A Review on Ontology Learning Approaches of Creating a Topic Map of Cybercrime Research
Authors: Lee Kijung 
Published: February 2019

Conducting an academic research requires getting a firm grasp of ongoing research issues as well as locating research materials effectively. Often research in different fields on a similar topic can assume diverse approaches due to different objectives and research goals in their own fields. Especially in an interdisciplinary research field like cybercrime, many research topics overlap with those of other research fields. Researchers in such a field, therefore, can benefit from understanding the related domains of one’s own research. Topic maps provide methods for understanding research domain and managing relevant information resources at the same time. In this paper, we review a topic map solution to acquire knowledge structure and to locate information resources effectively. We address current problems of cybercrime research, review previous studies that use automated methods for topic map creation, and examine existing sets of methods for automatically extracting topic map components. Especially, the methods we discuss here are text mining techniques for extracting ontology components, denoted as ontology learning.
Rejection in heart transplantation for cardiac sarcoidosis mimicking idiopathic giant cell myocarditis: long-term follow-up
Authors: Di Nora Concetta , Miani Daniela , Sponga Sandro , Livi Ugolino 
Published: February 2019

Heart transplantation is a life-saving therapy for some patients admitted for acute myocarditis. However, controversial exists about the major risk of rejection following heart transplantation in specific types of myocarditis. Because of relatively few data on the post heart transplant outcomes, we report the long-term follow-up of a 39-year-old patient with a previous history of ulcerative colitis, which rapidly worsened heart failure until an emergency heart transplant in 2004.
The clinical course was complicated by many episodes of rejection; lastly, after the development of severe cardiac allograft vasculopathy, re-heart transplantation was needed. The main findings of this case are: 1) inflammatory aetiology should always be suspected in patients with concomitant autoimmune disease that developing rapidly progressing heart failure; 2) patients with inflammatory myocardial disease undergoing heart transplantation should also undergo strict immunological surveillance; 3) the option of performing the re-heart transplant in a patient with a so complex management in the first one could be uncertain, but in this case the young age and lack of noncardiac comorbidities were effective to favour the survivor after two immunologically so challenging heart transplantation.
Comparison of the racing performance of Thoroughbreds with versus without osteochondral fragmentation of the accessory carpal bone identified on yearling sales repository radiographs
Authors: Davern Alec J. , Peloso John G. , Hawkins Jan F. , Moore George E. , Morehead James P. 
Published: February 2019

Abstract
OBJECTIVE To evaluate 2- and 3-year-old and career race performance of Thoroughbred racehorse prospects with and without osteochondral fragmentation of the accessory carpal bone (ACB) identified on yearling presale radiographs.
DESIGN Retrospective, matched cohort study.
ANIMALS 47 nonlame Thoroughbreds with (exposed cohort) and 94 nonlame Thoroughbreds without (unexposed cohort) osteochondral fragmentation of ACB facture identified on yearling sales repository radiographs.
PROCEDURES Repository radiographic interpretation reports for September yearling sales of a large Kentucky auction house from 2005 through 2012 were reviewed, and race records were collected and analyzed. Race performance was compared between horses with and without ACB fracture chosen from the same sale to identify associations between racing performance and ACB fracture.
RESULTS No significant differences were identified between horses with or without ACB fracture in their incidence of starting a race as a 2- or 3-year-old and the number of races started, earnings, or earnings per start for 2- or 3-year-old or career race performance. There was no significant difference in performance between horses with or without concurrent carpal osteoarthritis, nor did performance differ between horses with ACB fracture alone and those with ACB fracture and other radiographic abnormalities found to be associated with poorer performance in previous studies.
CONCLUSIONS AND CLINICAL RELEVANCE ACB fracture with or without carpal osteoarthritic changes identified on repository radiographs of Thoroughbred yearlings was not associated with poorer racing performance or lower likelihood of starting a race as a 2- or 3-year-old, compared with outcomes for unaffected horses.
Usefulness of caudomedial-craniolateral oblique radiographic views for the diagnosis of injury to the origin of the cranial cruciate ligament in two horses
Authors: Aldrich Ellison D. , Goodrich Laurie R. , Contino Erin K. , Kawcak Christopher E. , Barrett Myra F. , King Melissa R. , Valdés-Martínez Alejandro 
Published: February 2019

Abstract
CASE DESCRIPTION A 12-year-old mixed-breed mare (horse 1) and 6-year-old Friesian gelding (horse 2) were examined for chronic lameness associated with the stifle joint.
CLINICAL FINDINGS Lameness examination revealed effusion of the right (horse 1) or left (horse 2) femoropatellar and medial femorotibial joints and grade 3/5 (horse 1) or 4/5 (horse 2) lameness. A diagnosis of cranial cruciate ligament (CCL) injury with associated mineralization and avulsion (horse 1) or mineralization alone (horse 2) was facilitated in both horses with a caudomedial-craniolateral oblique radiographic view obtained 45° medial to the caudocranial line, which highlighted the origin of the ligament on the caudoaxial aspect of the lateral femoral condyle within the intercondylar fossa. These lesions were subsequently confirmed via CT.
TREATMENT AND OUTCOME Arthroscopy of the medial and lateral femorotibial joints was performed for horse 1 and revealed the osseous fragment associated with the CCL, but the fragment could not be removed. Horse 2 was euthanized while anesthetized following CT owing to the poor prognosis.
CONCLUSIONS AND CLINICAL RELEVANCE Radiography is typically the first imaging modality attempted for horses with CCL injury, particularly outside the hospital setting. A 45° caudomedial-craniolateral oblique radiographic view may aid in diagnosis of CCL injury when avulsion or mineralization is present. Although this view is not commonly included in the typical radiographic series for imaging of the stifle joint in horses, it should be considered when CCL injury is suspected.
A Practical and Historical Perspective of the How and Why of Whitening Fossil Specimens and Casts as a Precurser to Their Photography
Authors: Parsley Ronald L. , Lawson Mary H. , Pojeta Jr. John 
Published: February 2019

Abstract
Whitening fossils and casts to enhance photographic detail has evolved from the early twentieth century in step with advances in photography in both film and digital technologies. Whitening began with clouds of NH4OH and HCl being blown together to form a fine white coating of NH4Cl. The wet method has disadvantages in not being very stable and forms thick coatings in humid environments. Heating dry NH4Cl in a calcium chloride drying tube and variously expelling it in a concentrated vapor came into use in the mid twentieth century. It is a more advantageous method and the one commonly used by most invertebrate palaeontologists. Most dry methods differ in delivery of air to the heated drying tube (blowing over superheated NH4Cl) - directly by mouth, squeeze bulb, aquarium aerator, compressed gas bottle, or from a centralized compressed air system. It produces a fine-grained coating and works best when performed in a fume hood. Heating antimony in a drying tube or burning magnesium ribbon to produce whitening vapor or blowing fine grained powder with an airbrush have their adherents but are rarely used. Whitening electronically is a technique in its infancy but holds a great promise, especially in photography of large invertebrates and vertebrates.