bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tumor Size Affects Efficacy of Adjuvant Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma and Microvascular Invasion
Authors: Liu Shuang , Li Hui , Guo Lei , Zhang Bo , Zhou Binghai , Zhang Wentao , Zhou Jian , Fan Jia , Ye Qinghai 
Published: December 2018

Abstract

Background
Patients with hepatocellular carcinoma (HCC) and microvascular invasion (mVI) have shown dismal postoperative prognosis; however, whether adjuvant transarterial chemoembolization (TACE) can improve their outcomes remains unclear.

Materials and Methods
We retrospectively identified 549 eligible patients to form the crude cohort and adopted propensity score matching method to assemble another cohort of 444 patients with similar baseline characteristics. We assessed the effects of adjuvant TACE by stratified analyses and multivariate Cox analyses in two cohorts.

Results
There was significant interaction between tumor size and adjuvant TACE with respect to overall survival (OS; p = .006 for interaction). In the matched cohort, patients who received adjuvant TACE showed higher rates of 5-year OS (72.4% vs. 50.9%, p = .005) and 5-year recurrence-free survival (50.5% vs. 36.4%, p = .003) in the tumor ≤5 cm subgroup, but not in the tumor &gt;5 cm subgroup (32.3% vs. 24.9%, p = .350 and 18.8% vs. 19.7%, p = .180). The independent protective role of adjuvant TACE on OS was observed in patients with tumor ≤5 cm (adjusted odds ratio [OR] = 0.59, 95% confidence interval [CI] 0.36–0.97) but not in patients with tumor &gt;5 cm (adjusted OR = 1.17, 95% CI 0.84–1.62). The effects of adjuvant TACE did not change materially while the analysis was performed in the crude cohort.

Conclusion
For patients with HCC and mVI, adjuvant TACE was associated with improved outcomes, but not for those with tumor &gt;5 cm, according to the current protocol.

Implications for Practice
The outcomes of patients with hepatocellular carcinoma and microvascular invasion who received adjuvant transarterial chemoembolization were inconsistent in this study. According to the current protocol, adjuvant transarterial chemoembolization was associated with improved prognosis in patients with microvascular invasion, except for those with tumor &gt;5 cm. Multivariate Cox models confirmed adjuvant transarterial chemoembolization was an independent protective factor in the tumor ≤5 cm subgroup but not in the tumor &gt;5 cm subgroup.
Patient-Reported Toxicities During Chemotherapy Regimens in Current Clinical Practice for Early Breast Cancer
Authors: Nyrop Kirsten A. , Deal Allison M. , Shachar Shlomit S. , Basch Ethan , Reeve Bryce B. , Choi Seul Ki , Lee Jordan T. , Wood William A. , Anders Carey K. , Carey Lisa A. , Dees Elizabeth C. , Jolly Trevor A. , Reeder-Hayes Katherine E. , Kimmick Gretchen G. , Karuturi Meghan S. , Reinbolt Raquel E. , Speca JoEllen C. , Muss Hyman B. 
Published: December 2018

Abstract

Background
This study explores the incidence of patient-reported major toxicity—symptoms rated “moderate,” “severe,” or “very severe”—for chemotherapy regimens commonly used in early breast cancer.

Patients and Methods
Female patients aged 21 years or older completed a validated Patient-Reported Symptom Monitoring instrument and rated 17 symptoms throughout adjuvant or neoadjuvant chemotherapy. Fisher's exact tests compared differences in percentages in symptom ratings, and general linear regression was used to model the incidence of patient-reported major toxicity.

Results
In 152 patients, the mean age was 54 years (range, 24–77), and 112 (74%) were white; 51% received an anthracycline-based regimen. The proportion of patients rating fatigue, constipation, myalgia, diarrhea, nausea, peripheral neuropathy, and swelling of arms or legs as a major toxicity at any time during chemotherapy varied significantly among four chemotherapy regimens (p &lt; .05). The mean (SD) number of symptoms rated major toxicities was 6.3 (3.6) for anthracycline-based and 4.4 (3.5) for non-anthracycline-based regimens (p = .001; possible range, 0–17 symptoms). Baseline higher body mass index (p = .03), patient-reported Karnofsky performance status ≤80 (p = .0003), and anthracycline-based regimens (p = .0003) were associated with greater total number of symptoms rated major toxicities (alternative model: chemotherapy duration, p &lt; .0001). Twenty-six percent of dose reductions (26 of 40), 75% of hospitalizations (15 of 20), and 94% of treatment discontinuations (15 of 16) were in anthracycline-based regimens.

Conclusion
Capturing multiple toxicity outcomes throughout chemotherapy enables oncologists and patients to understand the range of side effects as they discuss treatment efficacies. Continuous symptom monitoring may aid in the timely development of interventions that minimize toxicity and improve outcomes.
Theory of mind abilities and its relationship with clinical features in euthymic bipolar patients
Authors: ATEŞ BUDAK Elif , KÜÇÜKGÖNCÜ Suat , BEŞTEPE Engin Emrem 
Published: December 2018

Purpose: The term of ‘Theory of mind’ (ToM), is the ability
to understand one’s own others’ mental states, is an important capacity for
social cognition and there is increasing data that theory of mind is
compromised in bipolar patients even in euthymic periods. The aim of this study
was to investigate theory of mind deficits in euthymic bipolar disorder
patients and its relation to the clinical features. Materials and method:Fifty two euthymic patients with bipolar I disorder
according to DSM IV-TR and 60 matched healthy control subjects were involved
in this study. ToM was assessed by Reading the Mind in the Eyes test and the
Dokuz Eylül Theory of Mind Scale.

Results: The patient group had significantly lower
performance on both of the ToM tests. We observed significant correlation
between age of onset, the number of hospitalizations, the number of manic/mixed
episodes and theory of mind performance.

Conclusion: The result we showed is that ToM is impaired in
euthymic bipolar I patients, which is consistent with the studies suggesting
that ToM might be a trait marker for bipolar disorder.
Hipertansiyon Hastalarının Özellikleri ile Sürekli Kaygı ve Baş Etme Becerileri Arasındaki İlişki
Authors: Uysal Zekai , Aslan Harun 
Published: December 2018

Amaç: Bu çalışmanın amacı hipertansiyon hastalarının sürekli kaygı düzeylerini, kullandıkları başa çıkma stratejilerini, sosyo-demografik özelliklerini, kaygı ve başa çıkma stratejileri arasındaki ilişkileri araştırmak ve tanımlamaktır. Gereç ve Yöntem:Çalışmada kaygı düzeyini ölçmek için 20 maddeden oluşan Sürekli Kaygı Ölçeği (STAI TX-2) ve başa çıkma stratejilerini ölçmek için (Carver ve ark. 1989) tarafından geliştirilen ve 28 maddeden oluşan Baş Etme (KF) ölçeğinden yararlanılmıştır. Bu çalışma, kesitsel tasarım ve kolayda örnekleme yöntemlerinin kullanıldığı bir tarama çalışmasıdır.Bulgular:Çalışmanın örneklemi Ankara Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi’nde hizmet alan hipertansiyon tanısı almış 147 kişi oluşturmaktadır. Çalışmaya katılan katılımcıların %57.1’i kadın katılımcıdır. Katılımcıların yaş ortalamaları 61.16±10.52 (ortalama±s.sapma) olarak elde edilmiştir. Katılımcıların %95.9’ u (n= 141) sürekli kaygı eşiği olan 42 puanı aşmıştır. Katılımcıların en çok kullandıkları problem odaklı başa çıkma stratejileri; din ve kabullenme stratejileriyken en çok kullanılan duygu odaklı başa çıkma stratejileri ise; dikkatini başka yöne yöneltme ve kendini suçlama stratejileridir.Sonuç:Sosyo-demografik ve sağlığa ilişkin özellikler, anksiyete ve başa çıkma stratejileri arasında önemli korelasyonlar bulunmuştur. Bulgular, hipertansiyonun psikososyal refah üzerindeki etkisini değerlendirirken bireysel baş etme stratejilerini dikkate almanın önemine işaret etmektedir
Comparison of Length of Stay and Deep Vein Thrombosis (DVT) Incidents in Dr. Soetomo Hospital
Authors: Hanindito Elizeus , Airlangga Prananda Surya , Sulistiawan Soni Sunarso , Semedi Bambang Pujo , Andriyanto Lucky , Utariani Arie , Rehatta Nancy Margarita 
Published: December 2018

Vein thrombosis may occur both in deep and superficial vein of all extremities. Ninety percent of vein thrombosis may progress into pulmonary embolism which is lethal. Deep vein thrombosis (DVT) is frequently found in critically ill patients in ICU, especially patients who are treated for a long time. This study aims to analyse the comparison between length of stay and DVT incidents in critically ill patients. A cross-sectional study was employed. We include all patients who were 18 years or older and were treated in ICU of Dr Soetomo public hospital for at least 7 days. The patients were examined with Sonosite USG to look for any thrombosis in iliac, femoral, popliteal, and tibial veins and Well’s criteria were also taken. This study showed that length of stay is not the only risk factor for DVT in patients treated in ICU. In our data, we found out that the length of treatment did not significantly cause DVT. Other risk factors such as age and comorbidities in patients who are risk factors may support the incidence of DVT events. The diagnosis of DVT is enforced using an ultrasound performed by an expert in the use of ultrasound to locate thrombus in a vein. Length of treatment is not a significant risk factor for DVT. Several other factors still need to be investigated in order for DVT events to be detected early and prevented.
FAKTOR PERILAKU PENGGUNAAN ALAT PELINDUNG DIRI (APD) PADA PEKERJA PT. X
Authors: Dahyar Chyntiya Permata 
Published: December 2018

Indonesia merupakan Negara berkembang yang memiliki banyak kekayaan alam sehingga kekayaan alam tersebut dapat dimanfaatkan dalam mengembangkan sektor-sektor yang ada di Indonesia salah satunya adalah sektor industri. Perkembangan sektor industri membuat adanya peralihan alat-alat yang bersifat manual menjadi mesin/peralatan yang lebih canggih yang dapat menimbulkan hal negatif seperti kecelakaan kerja. Kecelakaan kerja dapat terjadi disebabkan oleh unsafe conditions dan unsafe acts. Peningkatan sektor industri berbanding dengan peningkatan tenaga kerja sehingga harus berbanding lurus dengan perlindungan yang diberikan kepada tenaga kerja berupa Kesehatan dan Keselamatan Kerja pekerja. Perlindungan tersebut dapat dengan pengendalian kecelakaan kerja yang mana pengendalian kecelakaan kerja diperlukan untuk mengurangi dan mencegah terjadinya kecelakaan kerja yaitu dengan 5 hierarkhi pengendalian kecelakaan kerja yaitu eliminasi, substitusi, perancangan, administratif, dan alat pelindung diri. Perusahaan relatif menggunakan alat pelindung diri sebagai upaya terakhir dalam pengendalian kecelakaan kerja jika pengendalian lain sudah dilakukan namun masih terdapat potensi-potensi bahaya. Kecelakaan kerja juga disebabkan oleh unsafe behavior sehingga diperlukan perilaku pekerja dalam menggunakan alat pelindung diri. PT. X merupakan perusahaan Badan Usaha Milik Negara (BUMN) yang bergerak di bidang industri galangan kapal, yang kegiatan utamanya adalah memproduksi kapal dan perbaikan serta pemeliharaan kapal. PT.X memiliki program berbasis safety behavior seperti safety talk, induction, meeting, patrol, hingga sidak yang mengkaji terkait isu-isu kesehatan dan keselamatan kerja. Penelitian ini bertujuan untuk mengetahui faktor-faktor apa saja yang berhubungan dengan perilaku penggunaan alat pelindung diri (APD). Metode dalam penelitian ini adalah observasional analitik dengan pendekatan kuantitatif dan menggunakan desain cross sectional. Hasil penelitian ini menunjukan bahwa faktor yang mempengaruhi perilaku penggunaan alat pelindung diri adalah sikap. Sikap terbentuk dari persepsi manfaat, dan persepi kemudahan yang saling berhubungan signifikan terhadap sikap. Kata Kunci: perilaku, persepsi, manfaat, kemudahan, alat pelindung diri (APD), kecelakaan kerja.
Prevention of Stem-base Splitting in Cut Hippeastrum Flowers
Authors: Halevy Abraham H. , Kofranek Anton M. 
Published: December 2018

Abstract
Splitting and out-rolling of the stem bases in cut flowers of Hippeastrum Xhybridum was prevented by a 1-day-pulse treatment with 0.125 m sucrose. Pulsing also slightly increased vase life and promoted the opening of all the flower buds on the stem.
Potato Tuber Proteins as Molecular Probes for Tuberization
Authors: Park William D. 
Published: December 2018

Abstract
The potato has tremendous potential as a source of human food. Potato is second only to sugarcane in carbohydrate production and soybeans in protein production per hectare (6). Furthermore, the proteins in potato are of excellent nutritional quality, unlike those of most cereals and legumes (7, 8, 20). The potato combines these properties to produce more nutritious human food per hectare than any of the other major food crops (20).
In Vitro Propagation of Pecan Seedlings
Authors: Hansen Keith C. , Lazarte Jaime E. 
Published: December 2018

Abstract
Single-node cuttings obtained from 2-month-old seedlings of pecan [Carya illinoinensis (Wang.) K. Koch] were induced to break buds and form multiple shoots in liquid, woody plant medium (WPM) and 2% glucose supplemented with 6-benzylamino purine (BA) at 3 mg/liter. In vitro-derived shoots soaked in 1-3 mg/liter indolebutyric acid (IBA) produced adventitious roots in vitro; when soaked for 8 days in 10 mg/liter IBA, they were rooted successfully in soil and acclimated to greenhouse conditions. Etiolation of stock plants did not improve shoot proliferation or rooting under in vitro culture.
A Nondestructive System for Monitoring Gas Evolution from Small-sized Fruits in the Field
Authors: Lang Gregory A. , Martin George C. 
Published: December 2018

Abstract
A nondestructive system for measuring volatile compounds, specifically ethylene, evolved from intact fruit of olive (Olea europaea L.) in the field is described. Polyethylene cans from 35-mm film cartridges are modified with a rubber septum for sampling. The lid is sealed around the fruit peduncle and remains in the field under all conditions. The can is removable to expose the fruit to normal conditions when sampling is not being done. Samples of the atmosphere inside the can are taken with a syringe for gas chromatographic analysis. Background ethylene evolution from the system is low. The system allows repeated monitoring of the same fruit over the duration of a season. Nineteen glues and sealants are evaluated for bonding, phytotoxicity, and ethylene evolution.
AR Hale’s Best Jumbo, AR 5, and AR Topmark: Melon Aphid-resistant Muskmelon Breeding Lines
Authors: McCreight J. D. , Kishaba A. N. , Bohn G. W. 
Published: December 2018

Abstract
The melon (or cotton) aphid (Aphis gossypii Glover), an economically important pest throughout the world (1), is an important vector of muskmelon viruses (6), and often causes damage by feeding large populations on this favored host (7). Resistance to the melon aphid was found in muskmelon PI 371795 from India (4).
In Vitro Propagation of Dierama latifolium
Authors: Page Yvonne M. , Van Staden J. 
Published: December 2018

Abstract
Dierama latifolium N.E. Br. was propagated in vitro using corm cultures. Shoots were induced from corm explants when grown on solidified Murashige and Skoog (MS) medium supplemented with 30 g/liter sucrose, 100 mg/liter meso-inositol, and 0 or 0.5 mg/liter NAA. Shoot proliferation was not improved by the addition of BA to the initial culture medium. Multiple shoots were induced by transferring those produced in vitro, to a modified MS medium supplemented with 0.5 or 1.0 mg/liter BA. Rooting of these shoots was induced by subculturing single excised shoots, 5-10 mm in height, either a hormone-free basal medium or a BM supplemented with 0.5 or 1.0 mg/liter NAA. Utilizing this technique, about 90 plants could be produced from a single corm within 12 months. Chemical names used: 1-napthalenacetic acid (NAA); N-(phenylmethyl)-1H-purin-6-amine(BA).
Pesticide Spraying in Indian River Grapefruit: III. Opportunities for Improving Efficacy and Efficiency while Reducing Off-target Deposition
Authors: Stover Ed , Wilson Chris , Scotto Dominick , Salyani Masoud 
Published: December 2018

Parts I and II of this series revealed substantial opportunities for improving spraying of Indian River citrus (Citrus spp.). In this segment of our work we develop guidelines for growers to select the spray parameters providing an optimal balance between efficiency and efficacy while minimizing environmental contamination.It is proposed that these guidelines could be codified in a simple expert system to make them easier to use. We propose that understanding limiting conditions may be the key to choosing spray options. Wind is a major factor influencing spray deposition and offtarget drift. Based on weather records, wind speeds below 5 mph (8.0 km·h-1) are only routinely observed from 2000 HR until 0800 HR, making night spraying a good choice for low-volume applications. The importance of adjusting sprayer set-up for individual groves is demonstrated, with economic estimates of the cost of failing to make these adjustments. Routine use of careful sprayer adjustments is also likely to reduce off-target drift. Improvements in equipment and spray chemicals are also discussed. Use of non-orchard buffer areas and/or windbreaks appear to offer considerable opportunity for reducing off-site spray movement.
Novel Green Micro-Synthesis of Graphene-Titanium Dioxide Nano- Composites with Photo-Electrochemical Properties
Authors: Serour Nourwanda M. , Hammad Ahmed S.E. , El-Shazly Ahmed H. , El-Gayar Dina A. , Nosier Shaaban A. 
Published: December 2018

Background:
Graphene-Titanium dioxide nano-composite forms a very promising material
in the field of photo-electrochemical research.

Methods:
In this study, a novel environment-friendly synthesis method was developed to produce
well-distributed anatase nano-titanium dioxide spherical particles on the surface of graphene sheets.
This novel method has great advantages over previously developed methods of producing graphenetitanium
dioxide nanocomposites (GTNCs). High calcination temperature 650°C was used in the
preparation of nano titanium dioxide, and chemical exfoliation for graphene synthesis and GTNC
was performed by our novel method of depositing titanium dioxide nanoparticles on graphene sheets
using a Y-shaped micro-reactor under a controlled pumping rate with minimal use of chemicals.

Results:
The physiochemical and crystallographic properties of the GTNC were confirmed by TEM,
XRD, FTIR and EDX measurements, confirming process repeatability. Spherical nano-titanium dioxide
was produced in the anatase phase with very high crystallinity and small particle diameters
ranging from 9 nm to 25 nm, also the as prepared graphene (RGO) exhibited minimal flake folding
and a high carbon content of 81.28% with a low oxygen-to-carbon atomic ratio of 0.172 and GTNCs
produced by our novel method had a superior loading content, a homogeneous distribution and a
96.6% higher content of titanium dioxide particles on the graphene sheets compared with GTNCs
prepared with the one-pot method.

Conclusion:
For its photoelectrochemical properties, chronoamperometry showed that GTNC sample
(2) had a higher peak current of 60 μA compared with that of GTNC sample (1), which indicates
that the separation and transfer of electron-hole pairs are better in the case of GTNC sample (2) and
according to the LSV results, the generation of photocurrent in the samples can be observed through
multiple on-off cycles, which indicates that the electrodes are stable and that the photocurrent is quite
reversible.
Load Cells Application for Developing Weight-Bearing Detection via Wireless Connection
Authors: Jaysrichai Tossaphon 
Published: December 2018

Objective:To focus on a device development for measuring the weight-bearing on feet while simultaneously reporting data on smartphone usage. Secondly, the output data from this device are tested for the accuracy.Methods:Researcher used eight pieces of 50 kg Body Load Cell Weighing Sensor Resistance strain Half-bridge Original (four pieces per foot), two pieces of HX711 amplifier, MCS-51 AT89 C51 microcontroller and HC-05-Bluetooth to develop the device. This device that is called the Wireless Weight-Shifting Detector (WWSD) is used to measure weight-bearing on feet by being attached to sandals. The output data are simultaneously reported on smartphonevialine-graphs [load (kg) per sampling data] and numeric by FootpressV1 application. The device was tested using accurate measuring data with standard weights and calculated in percentage of accuracy (%). After that, WWSD was used to compare the weight-bearing measurement during standing with forceplate (AMTI; OR6-7 Platform).Results:The percentage of accuracy of WWSD was more than 97% and the error values from the measuring standard weights ranged under ±0.23 kg. The accuracy of measurement was more than 95% when compared with the force plate.Conclusion:WWSD can report simultaneously the weight-bearing on feet with rather accurate data on smartphone. It may be helpful in assisting physical therapists while training patients in clinic.
Passive Periodontal Sensation Threshold of Upper Molars in Patients with Myofascial Pain
Authors: Hirata Atsutoshi , Kato Seiya , Mude Acing Habibie , Oki Kazuhiro , Matsunaga Tadashi , Minagi Shogo 
Published: December 2018

Background and Objective:

The relationship between periodontal sensation and Myofascial Pain (MP) is not yet fully clarified. The aim of this study was to test the null hypothesis that there is no difference in the periodontal sensation threshold between subjects with MP and subjects with no Temporomandibular Disorders (TMD).

Methods:
Participants have clinically assessed in accordance with the Research Diagnostic Criteria for Temporomandibular Disorders version 1.0 guidelines and assigned to the MP group (mean age 54.8 ± 14.8 years; 1 male and 11 females) or the control group (mean age: 63.9 ± 13.2 years; 1 male and 15 females). The Passive Periodontal Sensation Threshold (PPST) was evaluated using impulsive mechanical stimulation on the occlusal surface parallel to the tooth axis of the maxillary first molar, if present. The difference in the mean PPST between the MP group and the control group was evaluated using the Student t-test after checking for homoscedasticity.

Results:
The mean PPST value was 1050.1 ± 480.3 mN in the MP group and 712.3 ± 288.5 mN in the control group. A significant difference was observed between these mean PPST values (p = 0.045).

Conclusion:
There was a significant difference in PPST between the MP group and the control group. Although the etiology of the change of PPST is still unknown, the higher PPST value observed in MP patients suggests that future study on occlusal dysesthesia or occlusal sensation-related pathosis is warranted.