bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphometric evaluation of the proximal tibiofibular joint among patients with knee joint pain: A pilot study and literature review
Authors: Sojat Jakub Krzysztof , Szlęzak Michał Jan , Zamarlik Marta Izabela , Bressler Kamil , Zieliński Maciej , Rajca Jolanta , Wilk Renata , Ficek Krzysztof , Likus Wirginia 
Published: November 2024

Objectives:
The proximal tibiofibular joint (PTFJ) serves as a crucial stabilizing component of the entire knee joint complex. Morphometric analysis of the PTFJ can lead to clinically significant conclusions for orthopedic specialists and physiotherapists. The aim of the study was to assess the values of the inclination angle of the PTFJ in the sagittal and coronal planes using magnetic resonance imaging in patients with knee pain.

Material and Methods:
Measurements of the inclination angle were conducted on 48 patients divided into three groups: Those with damaged medial meniscus (M), those with knee joint cartilage damage (Ca), and the control group (C), in which no deviations from normality were observed in the analyzed imaging study.

Results:
The mean values of the tibiofibular joint inclination angle in the frontal plane were as follows: (C) 16.927° ± 1.778; (Ca) 16.822° ± 2.537; (M) 14.958° ± 1.760. In the sagittal plane, the corresponding values were: (C) 38.155° ± 1.524; (Ca) 39.392° ± 1.927; (M) 37.471° ± 1.165. Although the mean tibiofibular joint inclination angle was lowest in the group with medial meniscus injury when compared to the control group, these differences did not reach statistical significance.

Conclusion:
Measuring and observing the variety of PTFJ inclination angles among patients are conducive to better understanding its influence on knee pain. The differences in the PTFJ inclination angle between groups in our pilot study were not statistically significant. Consequently, the study necessitates replication within a substantial population cohort.
Eksplorasi Dan Identifikasi Morfologi Benih Padi Lokal Dari Beberapa Wilayah Sumatra Barat
Authors: Zul Zulkarnaini , Gusmini Gusmini , Yasin Syafrimen 
Published: November 2024

Sumatra Barat adalah provinsi yang memiliki kekayaan akan sumber daya genetik tanaman, khususnya padi. Namun penggunaan varietas padi baru mengakibatkan padi lokal mulai terpinggirkan. Oleh karena itu, eksplorasi padi lokal menjadi sangat penting dalam upaya pelestarian sumber daya genetik. Padi lokal merupakan aset yang berharga bagi perbaikan tanaman untuk mendapatkan resistensi, baik biotik maupun abiotik. Tujuan penelitian ini adalah untuk melakukan ekplorasi padi lokal dan mengidentifikasi lokasi tumbuh serta melakukan karakterisasi penampilan gabah padi lokal yang berasal dari beberapa wilayah Sumatra Barat. Penelitian dilaksanakan pada bulan Agustus hingga September 2023. Tahapan penelitian meliputi survei lokasi keberadaan padi lokal, karakterisasi biji padi lokal, dan melakukan analisis jarak genetik. Dari hasil penelitian diperoleh 21 genotipe padi lokal Sumatra Barat yang diperoleh dari 5 kabupaten dan 1 kota. Hasil_karakterisasi morfologi biji menunjukkan adanya perbedaan sifat*kuantitatif-(panjang, lebar dan berat 100 biji serta panjang rambut) serta perbedaan sifat kualitatif (warna lemma dan warna pucat, bentuk_kariopsis(dan warna, perikardium).
Pengaruh Pupuk Gandasil D Dan Konsentrasi Atonik Terhadap Pertumbuhan Dan Produksi Tanaman Seledri (Apium grafeolens L.) Pada Media Tanam Pasir
Authors: Riry Johan , Nendissa Jeanne I. , Gomies Batseba E.L.L. 
Published: November 2024

Celery (Apium graveolens L.) adalah tanaman yang populer tidak hanya sebagai sayuran pelengkap dalam masakan tetapi juga karena memiliki sifat herbal yang dapat menyembuhkan berbagai penyakit. Untuk meningkatkan produksi seledri, pasokan nutrisi yang memadai sangat penting. Salah satu sumber nutrisi yang penting bagi seledri adalah pupuk Gandasil D dan Atonik sebagai Zat Pengatur Tumbuh (ZPT). Penelitian ini bertujuan untuk mengevaluasi efek pupuk Gandasil D dan konsentrasi Atonik terhadap pertumbuhan dan hasil produksi seledri menggunakan media tanam pasir. Dilakukan di Desa Ruamahtiga, Kecamatan Teluk Ambon, dari bulan Februari hingga Mei 2023, penelitian ini menggunakan desain acak kelompok dengan dua faktor: pupuk Gandasil D dengan 4 tingkatan dan dosis ZPT Atonik dengan 3 tingkatan, diulang 3 kali sehingga total 36 unit percobaan. Variabel yang diamati meliputi tinggi tanaman, jumlah anakan, jumlah daun, dan berat segar tanaman. Hasil analisis menunjukkan bahwa aplikasi pupuk Gandasil D pada konsentrasi 2,0 gram per liter air memberikan pengaruh yang signifikan terhadap semua parameter yang diamati. Aplikasi Gandasil D pada konsentrasi ini menghasilkan berat segar seledri sebesar 25,09 gram per rumpun, menandakan efektivitasnya dalam meningkatkan produksi tanaman. Penemuan ini menekankan pentingnya manajemen nutrisi yang tepat, seperti penggunaan pupuk Gandasil D dan Atonik, dalam meningkatkan produktivitas tanaman seledri. Selain itu, penelitian ini memberikan kontribusi pada pemahaman praktis tentang penggunaan optimal pupuk dan ZPT dalam budidaya seledri.
Eksplorasi Jamur Antagonis Pada Rizosfer Tanaman Kelapa (Cocos nucifera L.) Di Pulau Ambon
Authors: Ubaidillah Andi , Patty Jogeneis , Talahaturuson Abraham 
Published: November 2024

Pengendalian hayati merupakan suatu pemanfaatan mikroorganisme yang bertujuan untuk mengendalikan Organisme Pengganggu Tanaman (OPT). Adapun penelitian ini bertujuan untuk mendapatkan identifikasi jamur antagonis serta menguji daya hambat jamur tersebut terhadap Phytopthora palmivora. Penelitian dilaksanakan di lahan kebun kelapa milik petani di pulau Ambon dan di laboratorium Balai Besar Perbenihan dan Proteksi Tanaman Perkebunan (BBPPTP) Ambon, pada bulan Juni – Oktober 2023. Mengggunakan metode eksplorasi dan eksperimen di Laboratorium BBPPTP Ambon untuk uji antagonisme. Bahan yang digunakan yaitu tanah disekitar perakaran tanaman kelapa yang sehat. Pengambilan sampel dilakukan dengan metode Simple Random Sampling dan menetapkan 4 lokasi di Pulau Ambon. Kemudian sampel tanah dibawa ke laboratorium untuk dilakukan isolasi dan identifikasi serta uji antagonisme. Hasil eksplorasi jamur antagonis rhizosfer tanaman kelapa di pulau Ambon diperoleh empat genus jamur antagonis yaitu Trichoderma, Aspergillus, Rhizopus dan Mucor. Perkembangan penghambatan patogen Phytoptora palmivora oleh isolat Trichoderma menunjukkan bahwa masing-masing isolat tersebut memiliki daya antagonisme. Berdasarkan tingkatan kelas antagonismenya, isolat TrichoRKSW1, TrichoRKSW2, TrichoRKSW4, TrichoRKSW5, TrichoRKLH2, TrichoRKLH4, TrichoRKLH5, TrichoRKNL1, TrichoRKNL3, TrichoRKNL4 dan TrichoRKLBH3 dapat dikategorikan kedalam tingkat antagonisme kelas 1, sedangkan isolat TrichoRKNL2, TrichoRKLBH1, TrichoRKLBH4 dan TrichoRKLBH5 dapat dikategorikan kedalam tingkat antagonisme kelas 2. Isolat Aspergillus, Mucor dan Rhizopus termasuk kedalam tingkat kelas 3.
Study of the biochemical status of calves in the early postnatal period in connection with dyspepsia
Authors: Vasilyeva S. , Karpenko L. , Shiryaeva N. 
Published: November 2024

Purpose: to study changes in the most important metabolic parameters in case of dyspepsia in calves.Materials and methods. Two groups of calves of 8 heads each, aged from 6 to 14 days, were formed. The first group included calves with signs of dyspepsia, who, in addition to diarrhea syndrome, had decreased appetite, weakness, and signs of abdominal pain. At the time of the study, the duration of the illness was 2-4 days. The second (control) group included clinically healthy animals of the same age. Blood was taken from the calves from the jugular vein in the morning before feeding. Blood serum was examined in a clinical biochemical laboratory using standard test systems to determine biochemical parameters.Results. In calves with dyspepsia, a significant decrease in the concentration of triglycerides by 1,8 times, cholesterol by 1,57 times, total protein by 5,5 % and albumin by 12,3 % was revealed. They also revealed a significant increase in the activity of transamination enzymes — ALT (2,6 times) and AST (1,6 times), which may indicate both damage to hepatocytes and the induction of enzymes to accelerate transamination reactions in order to meet energy needs calf body. The studies did not reveal significant changes in the concentrations of urea, creatinine and bilirubin.Conclusion. Studies have revealed metabolic changes that occur due to decreased absorption of nutrients in the intestines. Damage to the intestinal mucosa leads not only to a deterioration in the absorption of nutrients, but also to the penetration of proteins, primarily albumins, into the intestinal lumen and their removal from the body into the external environment. Redistribution of metabolic pathways to ensure homeostasis plays an adaptive role, but subsequently can have a negative role in the processes of growth and development of the calf’s body.
Deer of the forest-tundra of the Magadan region
Authors: Bryzgalov G. 
Published: November 2024

Purpose: to study the morphological and economically useful traits of domestic reindeer (Rangifer tarandus L.) in the forest-tundra zone of the Far North-East of Russia.Materials and methods. The study used zootechnical information from annual reports on completed research projects by employees of the Laboratory of Selection and Breeding in Reindeer Husbandry of the Magadan Zonal Research Institute of Agriculture of the North-East for the 1970-1980s and 2000s. The model for the research was the reindeer population of the Markovsky state farm, typical for the forest-tundra zone of the North-East. The area of ​​reindeer pastures on the farm exceeded 5 million hectares, with 142.8 hectares per head. The average size of the production herd was 2,500 individuals.Results. The article presents data on morphological and economically useful traits of reindeer in the forest-tundra of the North-East — a pasture-geographical space on the border of the ranges of two large groups of reindeer — tundra and taiga. In the Markovsky state farm, typical for the forest-tundra zone, out of 35 thousand reindeer in the main herd, 25 % were Even, 44 % were Chukchi and 31 % were crossbred Chukchi-Even animals. In the forest-tundra, a hybrid population of reindeer was formed as a result of crossing two sympatric populations of the Even and Chukchi breeds. The intermediate phenotype had characteristic differences from the original breeds in morphological traits — color, exterior and constitution (linear measurements, body indexes), and meat productivity indicators. The conclusion is made about the origin of the forest-tundra ecotype based on hybrids from crossing sympatric populations of Chukchi and Even reindeer of different generations, backcrossing, introgression, stabilizing selection, microevolution under the influence of natural conditions and anthropogenic factors.
Tingimento natural em tecidos usando cascas dos frutos e serragem de madeira da Amazônia
Authors: Simões Pinto Sofia , Figueira Alves Letícia , Augusto Aguiar Ribeiro Gyovanni , Tunes Villani Fernanda 
Published: November 2024

Considerando a crescente preocupação com a sustentabilidade na indústria têxtil, o tingimento natural representa uma alternativa viável e ambientalmente amigável aos corantes sintéticos. O objetivo foi avaliar a eficácia do tingimento natural na produção de cores vibrantes e duradouras, bem como seu impacto socioeconômico nas comunidades locais da Amazônia. A metodologia incluiu a coleta e preparação da matéria prima e tingimento nos tecidos de algodão e seda. O estudo investigou o processo de tingimento natural em tecidos utilizando cascas dos frutos do tucumã e buriti e a serragem da madeira de andiroba, da região amazônica. Foram realizados testes de resistência à lavagem, desbotamento ao suor, salinidade e exposição solar para avaliar a durabilidade e qualidade dos tecidos tingidos. Os resultados demonstraram que os corantes naturais produziram cores vibrantes e duradouras nos tecidos, com resistência à lavagem e exposição solar. Além disso, o tingimento natural contribuiu para a geração de renda e valorização dos conhecimentos tradicionais das comunidades locais da Amazônia. Esses achados evidenciam o potencial do tingimento natural como uma alternativa sustentável e culturalmente significativa na indústria têxtil, promovendo a preservação ambiental e o desenvolvimento econômico das regiões produtoras.
¿Es relevante la distinción entre verdad y posverdad?
Authors: Silva-García Karina 
Published: November 2024

Introducción: Si bien el concepto de posverdad es relativamente reciente, este da cuenta de un fenómeno tan longevo como la política misma. La manipulación y la mentira siempre han estado presentes en los espacios políticos de interacción social, en este sentido la actualidad se distingue por el alcance y la velocidad con la que los discursos posverdaderos tienen lugar. Metodología: Desde el análisis crítico y reflexivo de diversos autores que han teorizado sobre el fenómeno de la posverdad, desde un enfoque filosófico discutimos al respecto de las dificultades que este fenómeno supone para el desarrollo de las democracias occidentales. Resultados: A partir de la revisión bibliográfica realizada, se observa cierta tendencia a, por una parte, reconocer el fenómeno de la posverdad como un fenómeno social y complejo. Por otra parte, considerar que la posverdad conduce al deterioro de las democracia en occidente. Conclusiones: A partir de lo anterior concluimos que es necesario dinamitar el concepto de posverdad. El desarrollo y consolidación de democracias reales solo está dado por la posibilidad de que los ciudadanos sean capaces de ejercer su libertad y autonomía, atributos que han sido directamente socavados por la cultura de posverdad.
Malignant transformation of vestibular schwannoma 29 years after Gamma Knife radiosurgery: illustrative case
Authors: Ishikawa Takayuki , Nagatani Tetsuya 
Published: November 2024

BACKGROUND
Vestibular schwannomas are common posterior fossa tumors, often managed with stereotactic radiosurgery (SRS) due to its low invasiveness and high tumor control rates. However, malignant transformation of vestibular schwannoma (MTVS) is a rare but serious complication with a poor prognosis.

OBSERVATIONS
The authors present a case of MTVS occurring 29 years after initial SRS, the longest latency reported. A 68-year-old woman developed sudden facial nerve paralysis, with magnetic resonance imaging revealing tumor regrowth. Surgical removal and histopathological analysis confirmed malignant transformation, characterized by spindle-shaped atypical cells and significant p53 positivity. Despite multiple surgeries and radiation therapy, the tumor exhibited rapid regrowth and cerebrospinal dissemination, leading to a poor prognosis.

LESSONS
This case underscores the critical importance of long-term monitoring after SRS, as malignant transformation can occur decades later. Additionally, it highlights the potential necessity for early intervention during malignant transformation to improve patient outcomes, despite the challenges in identifying effective treatments for MTVS.
https://thejns.org/doi/10.3171/CASE24526
Clazosentan-induced reversible focal brain edema in basal ganglia following aneurysmal subarachnoid hemorrhage treatment: illustrative case
Authors: Oishi Hiroyuki , Kato Takenori , Hasegawa Toshinori , Naito Takehiro , Mizuno Akihiro , Kageyama Akinori , Sakai Yosuke 
Published: November 2024

BACKGROUND
Clazosentan, a selective endothelin A receptor antagonist, effectively prevents cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Although various adverse effects have been reported, there have been no specific case reports of clazosentan-associated focal brain edema. This report highlights a rare complication associated with clazosentan treatment.

OBSERVATIONS
A female in her 70s with a subarachnoid hemorrhage underwent surgical clipping of a ruptured middle cerebral artery aneurysm and received clazosentan postoperatively. Six days after surgery, magnetic resonance imaging revealed high-intensity signals in the left basal ganglia on fluid-attenuated inversion recovery and apparent diffusion coefficient sequences without changes on diffusion-weighted imaging. The patient’s right-sided hemiparesis and disturbance of consciousness gradually progressed. On day 9, clazosentan was discontinued because of suspected adverse effects. Within approximately 2 weeks of discontinuation, both imaging findings and neurological symptoms improved. The temporal relationship between clazosentan administration, symptom onset, and improvement after discontinuation strongly suggested clazosentan-induced vasogenic edema.

LESSONS
Clazosentan can cause reversible localized vasogenic brain edema in the basal ganglia following subarachnoid hemorrhage treatment. This rare but significant complication underscores the importance of careful neurological monitoring and timely imaging in patients receiving clazosentan. Further research is required to understand the risk factors and mechanisms underlying this phenomenon.
https://thejns.org/doi/10.3171/CASE24567
Air Excess Coefficient and Irreversibility Value Analysis of Gas Turbines
Authors: Kaya Murat 
Published: November 2024

Gas turbines used in natural gas cycle power plants have been researched in terms of energy efficiency. Gas turbines used in power generation plants have a very complex structure because they contain many components. In order to determine the thermodynamic performance of this system, the efficiency of each component and the increase in entropy of each component were calculated using exergy analysis. Irreversibility was chosen as the main parameter and used for thermodynamic optimization of production. The system consists of many components. An increase in the irreversibility of a single component causes an increase in the irreversibility of other components. The effect of gas turbine pressure ratio and excess air percentage on fuel consumption, fuel exergy, combustion chamber exergy change and irreversibility change was investigated. It was observed that the increase in compressor pressure ratio increased irreversibility. Maximum irreversibility was observed in the combustion chamber. Irreversibility was compared with the excess air used in the combustion chamber. The air excess coefficient was examined as percentages of 100%, 200%, and 300%, respectively. The compression pressure ratio was examined for air excess coefficient percentage values from 3 to 40.
Aportes de la Gobernanza y la Participación Ciudadana a una Gestión de Pública Local focalizada en Políticas Públicas Autóctonas
Authors: Pachay-Laine Ana , Miranda-Pichucho Freddy 
Published: November 2024

La investigación tuvo como propósito interpretar los aportes de la gobernanza y la participación ciudadana a una gestión de pública local focalizada en políticas públicas autóctonas, teniendo como objeto de estudio la figura de los GADs cantonales; la metodología es de tipo fenomenológico e interpretativo con un enfoque cualitativo, soportada en una dimensión inductiva, cuyo objeto es encontrar un conocimiento que surge de abajo hacia arriba (de lo particular a lo general), los informantes están representados por investigadores expertos en la disciplina administración pública, y en especial en el área de la gobernanza y la participación ciudadana; entre los instrumentos utilizados para la recolección de información fue la observación directa (anotaciones en bloc de notas), y la entrevista semi estructurada (en profundidad), el método hermenéutico ha sido utilizado como estrategia de análisis, permitiendo, a través del proceso de comprensión e interpretación de los hallazgos, facilitar el proceso de identificación de categorías, mostrando vertientes que son vinculadas a la propuesta de valor público que representa la gobernanza institucional como buena praxis dentro de la gestión pública local; obteniéndose ente los hallazgos la posibilidad de incorporar a la gestión pública local una gobernanza pública estratégica, un laboratorio de gobierno / ciudadano, y la posibilidad de implementar una prestación proactiva de servicios.
Community Empowerment in Stunting Prevention: Implementation of the UBaMa Method (Ultra Violet Rays and Baby Massage)
Authors: Handayani Tinuk Esti , Rahayu Teta Puji 
Published: November 2024

Babies are an age group that is vulnerable to stunting. The incidence of stunting in Ngariboyo District in 2022 was 185 (13.14%) children under five, the highest occurred in Mojopurno Village, which was 49 (19.91%) children under five. The purpose of this activity is to improve the understanding, attitude and behavior of baby mothers in stimulation with the UBaMa method. The method carried out is to conduct a pre-test for baby mothers, followed by providing explanations and training on the UBaMa method. After that, the baby's mother was asked to carry out UBaMa at home, evaluated at the second meeting and so on until the fourth meeting. After the fourth meeting, a post-test was carried out. The results achieved were an improvement in the skills of mothers under five to do stimulation with the UBaMa Method with a proficiency of 68%. Knowledge Improvement with pre-test 49 and post-test 83.75. The UBaMa Stimulation Method (Ultra Violet and Baby Massage) can improve the growth and development of babies. It is recommended that the baby's mother periodically stimulate UBaMa at least 3 times a week to increase breast milk production so that it can be used to prevent stunting.
Non-invasive real-time investigation of colorectal cells tight junctions by Raman microspectroscopy analysis combined with machine learning algorithms for organ-on-chip applications
Authors: Calogiuri A. , Bellisario D. , Sciurti E. , Blasi L. , Esposito V. , Casino F. , Siciliano P. , Francioso L. 
Published: November 2024

IntroductionColorectal cancer is the third most common malignancy in developed countries. Diagnosis strongly depends on the pathologist’s expertise and laboratory equipment, and patient survival is influenced by the cancer’s stage at detection. Non-invasive spectroscopic techniques can aid early diagnosis, monitor disease progression, and assess changes in physiological parameters in both heterogeneous samples and advanced platforms like Organ-on-Chip (OoC).MethodsIn this study, Raman microspectroscopy combined with Machine Learning was used to analyse structural and biochemical changes in a Caco-2 cell-based intestinal epithelial model before and after treatment with a calcium chelating agent.ResultsThe Machine Learning (ML) algorithm successfully classified different epithelium damage conditions, achieving an accuracy of 91.9% using only 7 features. Two data-splitting approaches, “sample-based” and “spectra-based,” were also compared. Further, Raman microspectroscopy results were confirmed by TEER measurements and immunofluorescence staining.DiscussionExperimental results demonstrate that this approach, combined with supervised Machine Learning, can investigate dynamic biomolecular changes in real-time with high spatial resolution. This represents a promising non-invasive alternative technique for characterizing cells and biological barriers in organoids and OoC platforms, with potential applications in cytology diagnostics, tumor monitoring, and drug efficacy analysis.