bluuebunny/crossref_metadata_2025_split huggingface dataset:
La place de la famille en supervision d’équipe ou en analyse des pratiques professionnelles
Authors: Mellier Denis 
Published: June 2019

La problématique familiale peut être un risque ou une possibilité de travail en supervision d’équipe ou en analyse de la pratique. L’auteur s’appuie sur sa pratique clinique groupale. Il indique d’abord le risque du « familialisme » qui consiste à réduire l’institution à une famille ou à interpréter sans écart le problème des professionnels selon leur histoire personnelle. Il montre au contraire l’importance de considérer la place des familles des personnes accueillies dans l’institution car elles font partie des alliances et des organisateurs institutionnels. Après avoir indiqué comment ces deux dispositifs d’analyse sont centrés sur la professionnalité à l’instar d’un groupe Balint, il montre comment l’attention et les associations de points de vue des participants permettent de transformer le « négatif » de la problématique familiale des accueillis lors de la « construction de cas ».
Un poème typo-litho-graphique : Mallarmé, Redon, Un coup de dés
Authors: Illouz Jean-Nicolas 
Published: June 2019

« Je suis pour – aucune illustration », écrit Mallarmé, dans une formule qui écarte l’illustration en même temps qu’elle l’annexe au livre. L’article examine cette « fugue » entre images et texte dans le cas de l’édition Ambroise Vollard – demeurée édition fantôme – du poème Un coup de dés « illustré » par Redon : aux blancs de la typographie devaient faire écho les noirs des lithographies ; à la « mobilité de l’écrit » que catalyse le dépliement du volume devaient répondre les formes en formation que Redon puise aux sources de l’Inconscient ; en sorte que l’abstraction du poème se serait vue reconduite à sa source figurale enfouie : là où, dans le transfert d’art, se découvre, « muet », un enfant mystérieux, à jamais « tu ». Il en résulte une nouvelle « partition » entre les arts, réunis et séparés à la fois, sous l’égide de la Poésie, dans le jeu du Livre.
L’hymen des arts dans le livre Art nouveau : amour de loin et union libre
Authors: Barde Cyril 
Published: June 2019

En 1890, Maurice Denis appelait de ses vœux une décoration du livre « sans servitude du texte » consistant en « une broderie d’arabesques sur les pages, un accompagnement de lignes expressives ». L’ornementation linéaire qui investit le livre à la fin du siècle semble mettre en œuvre ce programme. Le livre devient alors un lieu où s’expérimentent de nouveaux nouages entre les arts et où s’inventent de nouveaux rapports entre lisible et visible. De l’amour de loin mis en abyme par l’ornementation de Mucha pour Ilsée, princesse de Tripoli à l’union libre du vers libre et de l’arabesque dans les éditions Deman en passant par le corps à corps de la reliure nancéienne, l’Art nouveau nous incite à filer la métaphore de l’hymen des arts effectué en mineur dans le livre considéré lui-même comme objet d’art.
Les Nouveaux Poèmes de Rilke : effleurer la sculpture de Rodin
Authors: Gheerardyn Claire 
Published: June 2019

Les études portant sur les relations entre les arts négligent le plus souvent la sculpture. Cet article examine l’« hymen » de la poésie et de la sculpture à travers le cas de Rilke qui, au contact de Rodin, a tenté de profondément transformer son œuvre. Tout en proclamant l’hétérogénéité de la sculpture et de la poésie, Rilke, dans un geste solennel, dédie au sculpteur ses Nouveaux Poèmes [ II ] ( Der neuen Gedichte anderer Teil , 1908). Il propose de prendre Rodin comme « immense exemple », alors même que le recueil ne décrit jamais les œuvres du sculpteur, mais les effleure de loin. Prendre Rodin pour modèle, c’est peut-être tenter de créer à la manière du sculpteur, mais c’est aussi inviter à lire comme Rodin lit les Fleurs du mal , en sculpteur. Les mains du lecteur qui touchent le poème pour explorer ses reliefs, continuent alors de créer le texte.
Competitive Readiness: Developmental Considerations to Promote Positive Youth Development in Competitive Activities
Authors: Kochanek Jillian , Matthews Alysha , Wright Emily , DiSanti Justin , Neff Michelle , Erickson Karl 
Published: June 2019

Competitive experiences have the potential to empower youth. Understanding the conditions under which young people can grow through competition is necessary to identify how competitive experiences can optimally support youth as engaged participants and people. This paper serves as a novel integration of previous research aimed toward practitioners. The purpose of this paper is to provide adult (and youth) leaders with empirically-based, practically meaningful guidance to integrate practices that support competitive readiness for youth development. To clarify the youth competitive readiness debate, this paper adopts a process-oriented, developmental perspective. We first define and provide background on youth development. Second, we put forth guiding postulates and their application to practice for organized competitive experiences for positive youth development promotion. We argue that youth are “ready” to compete not just when they can survive competitive experiences, but thrive through them. Interactions between individual, contextual, and developmental factors over time influence fluctuations in a young person’s state of competitive readiness. In this way, competitive readiness is an ongoing process that encompasses the individual needs of the child in relation to the environment.
An integrated population model sheds light on the complex population dynamics of a unique colonial breeder
Authors: Jansen Dorine Y. M. , Pradel Roger , Mares Rafael , Doutrelant Claire , Spottiswoode Claire N. , Covas Rita , Altwegg Res 
Published: June 2019

AbstractClimate models forecast increasing climatic variation and more extreme events, which could increase the variability in animal demographic rates. More variable demographic rates generally lead to lower population growth and can be detrimental to wild populations, especially if the particular demographic rates affected are those to which population growth is most sensitive. We investigated the population dynamics of a metapopulation of 25 colonies of a semi‐arid bird species, the sociable weaver Philetairus socius, and how it was influenced by seasonal weather during 1993–2014. We constructed an integrated population model which estimated population sizes similar to observed population counts, and allowed us to estimate annual fecundity and recruitment. Variance in fecundity contributed most to variance in population growth, which showed no trend over time. No weather variables explained overall demographic variation at the population level. However, a separate analysis of the largest colony showed a clear decline with a high extinction probability (0.05 to 0.33) within 5 years after the study period. In this colony, juvenile survival was lower when summers were hot, and adult survival was lower when winters were cold. Rainfall was also negatively correlated with adult survival. These weather effects could be due to increased physiological demands of thermoregulation and rainfall‐induced breeding activity. Our results suggest that the dynamics of the population on the whole are buffered against current weather variation, as individual colonies apparently react in different ways. However, if more and increasingly extreme weather events synchronize colony dynamics, they are likely to have negative effects.
Wnt/β‐catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind
Authors: Bem Joanna , Brożko Nikola , Chakraborty Chaitali , Lipiec Marcin A. , Koziński Kamil , Nagalski Andrzej , Szewczyk Łukasz M. , Wiśniewska Marta B. 
Published: June 2019

Canonical Wnt signaling, which is transduced by β‐catenin and lymphoid enhancer factor 1/T cell‐specific transcription factors (LEF1/TCFs), regulates many aspects of metazoan development and tissue renewal. Although much evidence has associated canonical Wnt/β‐catenin signaling with mood disorders, the mechanistic links are still unknown. Many components of the canonical Wnt pathway are involved in cellular processes that are unrelated to classical canonical Wnt signaling, thus further blurring the picture. The present review critically evaluates the involvement of classical Wnt/β‐catenin signaling in developmental processes that putatively underlie the pathology of mental illnesses. Particular attention is given to the roles of LEF1/TCFs, which have been discussed surprisingly rarely in this context. Highlighting recent discoveries, we propose that alterations in the activity of LEF1/TCFs, and particularly of transcription factor 7‐like 2 (TCF7L2), result in defects previously associated with neuropsychiatric disorders, including imbalances in neurogenesis and oligodendrogenesis, the functional disruption of thalamocortical circuitry and dysfunction of the habenula.
Copper‐Catalyzed C‐4 Carboxylation of 1‐Naphthylamide Derivatives with CBr4/MeOH
Authors: Sahoo Tapan , Sen Chiranjit , Singh Harshvardhan , Suresh E. , Ghosh Subhash Chandra 
Published: June 2019

AbstractA simple and practical copper catalyzed C‐4 carboxylation reaction of 1‐naphthylamide derivatives using carbon tetra bromide and methanol is reported here. Picolinamide and its derivatives are used as a bidentate directing group for the distal C4‐H functionalization. Various substituted naphthylamide derivatives, and anilides are employed for the carboxylation and proceeds in good yields under mild condition. From the outcome of experimental results, it is proposed that C4‐H carboxylation reaction of 1‐naphthylamides might proceed through a single electron transfer (SET) pathway.magnified image
Safety Assessment of Nanomaterials to Eyes: An Important but Neglected Issue
Authors: Zhu Shuang , Gong Linji , Li Yijian , Xu Haiwei , Gu Zhanjun , Zhao Yuliang 
Published: June 2019

AbstractThe production and application of nanomaterials have grown tremendously during last few decades. The widespread exposure of nanoparticles to the public is provoking great concerns regarding their toxicity to the human body. However, in comparison with the extensive studies carried out to examine nanoparticle toxicity to the human body/organs, one especially vulnerable organ, the eye, is always neglected. Although it is a small part of the body, 90% of outside information is obtained via the ocular system. In addition, eyes usually directly interact with the surrounding environment, which may get severer damage from toxic nanoparticles compared to inner organs. Therefore, the study of assessing the potential nanoparticle toxicity to the eyes is of great importance. Here, the recent advance of some representative manufactured nanomaterials on ocular toxicity is summarized. First, a brief introduction of ocular anatomy and disorders related to particulate matter exposure is presented. Following, the factors that may influence toxicity of nanoparticles to the eye are emphasized. Next, the studies of representative manufactured nanoparticles on eye toxicity are summarized and classified. Finally, the limitations that are associated with current nanoparticle‐eye toxicity research are proposed.
Diversity and temporal dynamics of primate milk microbiomes
Authors: Muletz‐Wolz Carly R. , Kurata Naoko P. , Himschoot Elizabeth A. , Wenker Elizabeth S. , Quinn Elizabeth A. , Hinde Katie , Power Michael L. , Fleischer Robert C. 
Published: June 2019

AbstractMilk is inhabited by a community of bacteria and is one of the first postnatal sources of microbial exposure for mammalian young. Bacteria in breast milk may enhance immune development, improve intestinal health, and stimulate the gut‐brain axis for infants. Variation in milk microbiome structure (e.g., operational taxonomic unit [OTU] diversity, community composition) may lead to different infant developmental outcomes. Milk microbiome structure may depend on evolutionary processes acting at the host species level and ecological processes occurring over lactation time, among others. We quantified milk microbiomes using 16S rRNA high‐throughput sequencing for nine primate species and for six primate mothers sampled over lactation. Our data set included humans (Homo sapiens, Philippines and USA) and eight nonhuman primate species living in captivity (bonobo [Pan paniscus], chimpanzee [Pan troglodytes], western lowland gorilla [Gorilla gorilla gorilla], Bornean orangutan [Pongo pygmaeus], Sumatran orangutan [Pongo abelii], rhesus macaque [Macaca mulatta], owl monkey [Aotus nancymaae]) and in the wild (mantled howler monkey [Alouatta palliata]). For a subset of the data, we paired microbiome data with nutrient and hormone assay results to quantify the effect of milk chemistry on milk microbiomes. We detected a core primate milk microbiome of seven bacterial OTUs indicating a robust relationship between these bacteria and primate species. Milk microbiomes differed among primate species with rhesus macaques, humans and mantled howler monkeys having notably distinct milk microbiomes. Gross energy in milk from protein and fat explained some of the variations in microbiome composition among species. Microbiome composition changed in a predictable manner for three primate mothers over lactation time, suggesting that different bacterial communities may be selected for as the infant ages. Our results contribute to understanding ecological and evolutionary relationships between bacteria and primate hosts, which can have applied benefits for humans and endangered primates in our care.
Role of inferior turbinate reduction in the quality of life of patients undergoing endoscopic sinus surgery for chronic rhinosinusitis
Authors: Soudry Ethan , Mace Jess , Smith Timothy L. , Hwang Peter H. 
Published: June 2019

BackgroundThe impact on quality of life (QoL) of bilateral inferior turbinate reduction (BITR) performed in the setting of endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) has been a point of controversy. The aim of this study was to determine whether addition of BITR to ESS is associated with improved QoL when compared with ESS alone.MethodsThis study presented findings a multi‐institutional, retrospective analysis of a prospective open cohort of patients electing ESS for failed medical management of CRS. QoL parameters were compared between patients who underwent ESS alone vs those who underwent ESS with BITR.ResultsA total of 571 patients with CRS who elected to undergo ESS were identified. Sixty‐one of these patients also underwent concurrent BITR, whereas 510 patients underwent ESS without BITR. Mean length of follow‐up was 15.1 months. Comparison between baseline and last postoperative QoL, olfaction, and endoscopic scores revealed significant improvement in both groups. Overall, BITR surgery was not significantly associated with clinically significant incremental improvement in QoL in either the polyp or non‐polyp group. Nevertheless, statistically significant improvement was noted for the nasal congestion/blockage symptom in polyp patients (p = 0.006) and in primary surgery patients (p = 0.027) who underwent BITR.ConclusionBITR in the setting of ESS for CRS is not associated with significant incremental improvement in overall QoL vs ESS alone. However, BITR in polyp and primary surgery patients undergoing ESS appears to offer a significant incremental improvement in nasal congestion/blockage symptoms compared with ESS alone. Future studies are warranted to better corroborate these findings.
Sub‐Micromolar Pulse Dipolar EPR Spectroscopy Reveals Increasing CuII‐labelling of Double‐Histidine Motifs with Lower Temperature
Authors: Wort Joshua L. , Ackermann Katrin , Giannoulis Angeliki , Stewart Alan J. , Norman David G. , Bode Bela E. 
Published: June 2019

AbstractElectron paramagnetic resonance (EPR) distance measurements are making increasingly important contributions to the studies of biomolecules by providing highly accurate geometric constraints. Combining double‐histidine motifs with CuII spin labels can further increase the precision of distance measurements. It is also useful for proteins containing essential cysteines that can interfere with thiol‐specific labelling. However, the non‐covalent CuII coordination approach is vulnerable to low binding‐affinity. Herein, dissociation constants (KD) are investigated directly from the modulation depths of relaxation‐induced dipolar modulation enhancement (RIDME) EPR experiments. This reveals low‐ to sub‐μm CuII KDs under EPR distance measurement conditions at cryogenic temperatures. We show the feasibility of exploiting the double‐histidine motif for EPR applications even at sub‐μm protein concentrations in orthogonally labelled CuII–nitroxide systems using a commercial Q‐band EPR instrument.
Active Template Synthesis of Protein Heterocatenanes
Authors: Da Xiao‐Di , Zhang Wen‐Bin 
Published: June 2019

AbstractCovalent‐bond‐forming protein domains can be versatile tools for creating unconventional protein topologies. In this study, through rewiring the SpyTag–SpyCatcher complex to induce rationally designed chain entanglement, we developed a biologically enabled active template for the concise, modular, and programmable synthesis of protein heterocatenanes both in vitro and in vivo. It is a general and good‐yielding reaction for forming heterocatenanes with precisely controlled ring sizes and broad structural diversity. More importantly, such heterocatenation not only provides an efficient means of bioconjugation for integrating multiple native functions, but also enhances the stability of the component proteins against proteolytic digestion, thermal unfolding, and freeze/thaw‐induced mechanical denaturation, thus opening up a versatile path in the nascent field of protein‐topology engineering.
Mechanotropic Elastomers
Authors: Donovan Brian R. , Fowler Hayden E. , Matavulj Valentina M. , White Timothy J. 
Published: June 2019

AbstractLiquid crystal elastomers (LCEs) are anisotropic polymeric materials. When subjected to an applied stress, liquid crystalline (LC) mesogens within the elastomeric polymer network (re)orient to the loading direction. The (re)orientation during deformation results in nonlinear stress‐strain dependence (referred to as soft elasticity). Here, we uniquely explore mechanotropic phase transitions in elastomers with appreciable mesogenic content and compare these responses to LCEs in the polydomain orientation. The isotropic (amorphous) elastomers undergo significant directional orientation upon loading, evident in strong birefringence and x‐ray diffraction. Functionally, the mechanotropic displacement of the elastomers to load is also nonlinear. However, unlike the analogous polydomain LCE compositions examined here, the isotropic elastomers rapidly recover after deformation. The mechanotropic orientation of the mesogens in these materials increase the toughness of these thiol‐ene photopolymers by nearly 1300 % relative to a chemically similar elastomer prepared from wholly isotropic precursors.
Highly Diastereoselective Synthesis of Syn‐1,3‐Dihydroxyketone Motifs from Propargylic Alcohols via Spiroepoxide Intermediates
Authors: Ding Xiao‐Bo , Furkert Daniel P. , Brimble Margaret A. 
Published: June 2019

AbstractSyn dihydroxyketone motifs are embedded in a wide range of biologically active natural products, however the development of stereoselective synthetic methods to assemble these structures has proven a challenging task. We report a highly diastereoselective method for the synthesis of syn dihydroxyketones from propargylic alcohols, with wide scope for application in natural product synthesis. The reaction sequence involves regioselective cyclisation of propargylic alcohols with incorporation of a triketone to give enol dioxolanes that are then diastereoselectively epoxidised to form unusual spiroepoxide intermediates. Hydrolysis affords syn dihydroxyketones as essentially single diastereisomers. The reaction sequence is operationally simple, of wide substrate scope, and remarkably can be efficiently carried out as a one‐pot process with no loss of overall yield or diastereoselectivity.
Degradation of carbon tetrachloride using ultrasound‐assisted nanoscaled zero‐valent iron particles@sulfur/nitrogen dual‐doped reduced graphene oxide composite: Kinetics, activation energy, effects of reaction conditions and degradation mechanism
Authors: Meng Fansheng , Ma Yiyang , Wang Yeyao 
Published: June 2019

We report a study of the synthesis of nanoscale zero‐valent iron particles stabilized by sulfur/nitrogen dual‐doped reduced graphene oxide (i.e. nZVI@SN‐rGO) and their applications as major reactants for the dechlorination of carbon tetrachloride (CT) by combining sonolysis with consideration of several operation parameters such as pH, temperature, catalyst dosage, as well as in the presence of common inorganic anions. The experimental results showed that the modified technology could remain effective for up to 180 min of reaction time under optimal conditions. Especially, there was no significant reduction in the removal efficiency toward CT even after five cycles, which was indicative of good stability. A study of the effects of common inorganic anions revealed that the presence of Clˉ and HCO3ˉ exhibited different positive effects in the following order: Clˉ > HCO3ˉ; NO3ˉ and SO42ˉ showed inhibition effects on CT removal. The structure and properties of nZVI@SN‐rGO were characterized using X‐ray diffraction, scanning electron microscopy, surface area analysis, Raman spectroscopy and X‐ray photoelectron spectroscopy. Additionally, the corresponding activation energy was approximately 31.04 kJ mol−1, suggesting that the surface chemical reaction rather than diffusion was the rate‐limiting step in the CT decomposition process. More importantly, the possible reaction mechanism and dechlorination pathway of CT using the ultrasound‐assisted nZVI@SN‐rGO system were also investigated.
Promising photoluminescence optical approach for triiodothyronine hormone determination based on smart copper metal–organic framework nanoparticles
Authors: Sheta Sheta M. , El‐Sheikh Said M. , Abd‐Elzaher Mohkles M. 
Published: June 2019

A copper metal–organic framework nanoparticles (Cu‐MOF‐NPs) synthesized via simple technique. The prepared Cu‐MOF‐NPs nanoparticles were further characterized using 1H‐NMR, FE‐SEM/EDX and thermal study (DSC/TGA). The FE‐SEM/EDX, thermal analysis, and NMR spectrum data with the other analysis support the nano‐Cu‐MOF structure and the monomeric unit (n[Cu (AIP)2(APY)(H2O)2].4H2O) of Cu‐MOF‐NPs. The photoluminescence (PL) studies of triiodothyronine hormone (T3) based on the prepared Cu‐MOF‐NPs investigated. The results revealed that the Cu‐MOF‐NPs might be used as a biosensor in the determination of triiodothyronine hormone (T3) in biological fluids through a significant quenching of the photoluminescence intensity of Cu‐MOF‐NPs at excitation wavelength 492 nm. The calibration plot achieved over the concentration range 0.0–200.0 ng/dL T3 hormone with a correlation coefficient 0.996 and limit of detection (LOD) and quantification (LOQ) 0.198 and 0.60 ng/dL, respectively. The PL spectra are indicating that Cu‐MOF‐NPs has highly selective sensing properties for T3 hormone without interfering with other human many hormones types. This approach considered a promising analytical tool for early diagnosis of the cases of thyroid disease. The mechanism of quenching between the Cu‐MOF‐NPs, and T3 hormone studied. The mechanism was a dynamic type and obtained due to the energy transfer mechanism.