bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expansive carotid artery remodeling: possible marker of vulnerable plaque
Authors: Yoshida Kazumichi , Yang Tao , Yamamoto Yu , Kurosaki Yoshitaka , Funaki Takeshi , Kikuchi Takayuki , Ishii Akira , Kataoka Hiroharu , Miyamoto Susumu 
Published: October 2019

OBJECTIVEAccumulated findings in the pathophysiology of atherosclerosis have demonstrated that not only luminal narrowing but also plaque characteristics influence the risk of future ischemic events. The morphology of the carotid artery (CA) changes in response to atherosclerotic development by expansive remodeling (ER), the clinical significance of which remains unclear. This study aimed to define associations between ER and local risk factors, including CA geometry and traditional systemic risk factors for ischemic events, to determine whether ER could serve as a clinical marker of carotid vulnerable plaque.METHODSThe authors retrospectively analyzed 66 patients with CA stenosis who were scheduled to undergo carotid endarterectomy or CA stenting. They calculated ER ratios in the internal CA (ICA) from long-axis MR images and as the maximal distance between the lumen and the outer borders of the plaque perpendicular to the axis of the ICA/the maximal luminal diameter of the distal ICA at a region unaffected by atherosclerosis. Relative overall signal intensity (roSI) was calculated to assess intraplaque hemorrhage and defined as the signal intensity of plaque on an axial T1-weighted image with maximal stenosis relative to that of the adjacent sternocleidomastoid muscle. The authors evaluated CA geometry by calculating the angles between the common CA (CCA) and ICA, and between the CCA and external CA (ECA) using digital subtraction angiography. The ER ratios, age, sex, percentage of stenosis, roSI, hypertension, hyperlipidemia, low-density lipoprotein, statin medication, diabetes, smoking habit, and ischemic heart disease were compared between 33 symptomatic and 33 asymptomatic patients. The authors also compared symptomatic status, age, sex, percentage of stenosis, ICA angle, ECA angle, roSI, and other traditional atherosclerotic risk factors between groups with extensive and slight ER.RESULTSThe ER ratio was significantly greater in symptomatic than in asymptomatic patients (1.91 ± 0.46 vs 1.68 ± 0.40, p < 0.05). The ICA angle was significantly larger in the group with extensive ER than in those with slight ER (33.9° ± 20.2° vs 21.7° ± 13.8°, p < 0.01). The roSI, ECA angle, percentage stenosis, or any other traditional vascular risk factors were not associated with ER.CONCLUSIONSCarotid ER might be an independent indicator of carotid vulnerable plaque, which should be validated in a longitudinal study of patients with carotid atherosclerosis, including those with nonstenotic to moderate stenosis.
Predominance of M1 subtype among tumor-associated macrophages in phenotypically aggressive sporadic vestibular schwannoma
Authors: Perry Avital , Graffeo Christopher S. , Carlstrom Lucas P. , Raghunathan Aditya , Driscoll Colin L. W. , Neff Brian A. , Carlson Matthew L. , Parney Ian F. , Link Michael J. , Van Gompel Jamie J. 
Published: October 2019

OBJECTIVETumor-associated macrophages (TAMs) have been implicated as pathologic actors in phenotypically aggressive vestibular schwannoma (VS), potentially mediated via programmed death-ligand 1 (PD-L1). The authors hypothesized that PD-L1 is a key regulator of the VS immune microenvironment.METHODSForty-six consecutive, radiation-naïve, sporadic VSs that were subtotally resected at primary surgery were assessed via immunohistochemical analysis, including analysis of CD163 and PD-L1 expression. Pathologic data were correlated with clinical endpoints, including tumor control, facial nerve function, and complications.RESULTSBaseline parameters were equivalent between stable and progressive post–subtotal resection (STR) VS. CD163 percent positivity and M2 index were significantly increased among tumors that remained stable (34% vs 21%, p = 0.02; 1.13 vs 0.99, p = 0.0008), as well as patients with favorable House-Brackmann grade I or II facial nerve function (31% vs 13%, p = 0.04; 1.11 vs 0.97, p = 0.05). PD-L1 percent positivity was significantly associated with tumor progression (1% vs 11%, p = 0.01) and unfavorable House-Brackmann grade III–VI facial nerve function (1% vs 38%, p = 0.02). On multivariate analysis, PD-L1 was independently significant in all models (likelihood ratio 4.4, p = 0.04), while CD163 was dependent in all iterations.CONCLUSIONSIn contrast to prior reports, in this study, the authors observed significantly increased levels of M1, CD163+ TAMs in association with VS that progressed after STR. Progressive tumors are characterized by increased PD-L1, potentially highlighting a mechanism of immune evasion that results in TAM deactivation, tumor growth, and further infiltration of anti-tumor immune cells. Targeting PD-1/PD-L1 may offer therapeutic promise, particularly in the setting of disease control after STR.
Menciptakan Wirausaha Budidaya Ikan Lele dengan Sistem Bioflok
Authors: Nasution Muhammad Irfan , Prayogi Muhammad Andi , Jufrizen Jufrizen 
Published: October 2019

<p>The Community Partnership Program has the theme of making community groups become entrepreneurs of catfish farming with biofloc ponds in Desa Marindal II Kec. Patumbak, Kabupaten Deli Serdang North Sumatra Province, encourages the empowerment of community groups towards productive entrepreneurs. This PKM has a short-term program that is to increase the ability to think and improve skills. The Community Partnership Implementation Program was held for 12 months with 2 PKM Partners namely 1) Marindal II Village Community Group and Joint Farmer Group. This PKM stage includes preparation, survey and location collection, analysis of potential and problems, focus group discussions (FGD), implementation of activities, monitoring and evaluation. The method used is using participatory participation methods, community empowerment, evaluation discussions, and monitoring. The output generated by the Community Partnership Program consists of 2 units of Bioflok catfish ponds, Catfish Seeds for enhancement, increasing competitiveness, the creation of new entrepreneurs in the community, producing catfish products, increasing science and technology in society and improving community governance that produces security.<br />Kata kunci: Community, Empowerment, Entrepreneurship, Catfish, Cultivation</p><p>Abstrak</p><p>Program Kemitraan Masyarakat (PKM) bertemakan menciptakan kelompok masyarakat menjadi wirausaha budidaya ikan lele dengan kolam bioflok di Desa Desa Marindal II Kec. Patumbak Kabupaten Deli Serdang Provinsi Sumatera Utara, bertujuan untuk pemberdayaan kelompok masyarakat menjadi wirausaha yang produktif. PKM ini memiliki program jangka pendek yaitu untuk meningkatkan kemampun berfikir dan keterampilan berusaha. Pelaksanaan Program Kemitraan Masyaraka (PKM) dilaksanakan selama 12 bulan dengan 2 Mitra PKM yaitu 1) Kelompok Masarakat Desa Marindal II dan Kelompok Tani Bersama. Tahapan PKM ini meliputi tahap persiapan, survei dan identifikasi lokasi, analisis potensi dan masalah, focuss group discussion (FGD), pelaksanaan kegiatan, monitoring dan evaluasi. Metode yang digunakan adalah dengan menggunakan metode pendekatan melalui pendekatan participatory , community empowerment, tahap evaluasi dan monitoring. Luaran yang dihasilkan PKM ini adalah 2 unit kolam ikan lele Bioflok, Benih Ikan Lele untuk Pembesaran, peningkatan daya saing, terciptanya wirausaha baru di masyarakat, menghasilkan produk ikan lele, peningkatan ipteks di masyarakat dan perbaikan tata nilai masyarakat berupa ketentaraman.<br />Kata kunci: Pemberdayaan, masyarakat, wirausaha, Budidaya, Ikan Lele</p><p> </p>
Pemetaan Area Risiko Sanitasi Sektor Air Limbah Domestik Kota Cimahi
Authors: Yasya Heksantia Rahmadinda , Juwana Iwan 
Published: October 2019

<p class="Abstrak">Cimahi is one of developing cities in Indonesia that has sanitation condition with low services, especially in domestic wastewater management. In 2016, the coverage of domestic wastewater services in the city only reached 68.17%. In consequences, some communities discharging their wastewater to the stream. This matter could lead to water pollution that would indirectly affecting public health. Based on these problems, this reserach was carried out to calculate the level of risk in each urban village of Cimahi. The risk level is stated in the form of scores (1-4) with a description of 1 is very low risk; 2 is low risk; 3 is high risk; 4 very high risk. The risk calculation considers the determinants (exposure and impact) which consist of percentage of wastewater service, risk index, perceptions of related regional organizations, population, population density, poverty rates, and regional categories. The results obtained from the calculation of the risk of domestic wastewater in Cimahi show that the Pasirkaliki, Cibabat, Citeureup, Cipageran, Baros, and Cibeber have a very low risk; Cimahi and Utama are at low risk; Karangmekar, Cigugur Tengah and Cibeureum are at high risk; Padasuka, Setiamanah, Leuwigajah and Melong have a very high risk.</p>
PEMERIKSAAN TELUR SOIL TRANSMITTED HELMINTHS PADA KOTORAN KUKU PEMULUNG DI TEMPAT PEMBUANGAN AKHIR (TPA) SAMPAH
Authors: Widodo Agus , Ikawati Kartika 
Published: October 2019

<p>Kebiasaan buruk pemulung yang tidak mengindahkan pengelolaan sampah dan kebersihan diri mengakibatkan bakteri dan parasit khususnya <em>Soil Transmitted Helminths </em>dapat dengan mudah menginfeksi. <em>Soil Transmitted Helminths </em>terdiri dari:<em> A</em><em>scaris lumbricoides</em>, <em>Necator americanus, Ancilostoma duodenale, Trichuris trichiura, </em>dan <em>Strongiloides stercoralis. </em>Pemulung sangat rentan terinfeksi telur <em>Soil Transmitted Helminths </em>tersebut. Tujuan penelitian ini untuk mengetahui adanya infeksi <em>Soil Transmitted Helmiths </em>pada kotoran kuku pemulung di Tempat Pembuangan Akhir (TPA) Sampah Jatibarang Kecamatan Semarang Barat. Jenis penelitian ini adalah deskriptif dengan sampel sebanyak 67 orang yang diambil dengan teknik random sampling. Sebagai obyek penelitian adalah kuku pemulung yang diperiksa dengan metode Pengapungan NaCl jenuh. Prinsip dari metode ini yaitu mengapungkan parasit yang ada di kuku dengan pelarut yang berat jenisnya lebih tinggi dari berat jenis parasit. Dengan pelarut NaCl jenuh, maka parasit akan terapung. Berdasarkan pemeriksaan dari 64 sampel (37 perempuan dan 30 laki-laki) didapatkan hasil positif <em>A.lumbricoides </em>7 orang<em> </em>(10,5 %), Cacing tambang 0 (0 %), <em>T.trichiura </em>5 orang<em> </em>(7,4 %), dan <em>S.stercoralis </em>0 (0 %). Pada kasus infeksi ganda didapatkan hasil 1 orang wanita (2,7 %) terkontamisasi <em>A. Lumbricoides </em>dan <em>T. Trichiura , </em>dan 1 orang laki-laki (3,3 %) terkontamisasi <em>A. Lumbricoides </em>dan <em>T. Trichiura.</em> Semarang.</p>
Correlation between sowing time of maize hybrids, yield and seed moisture content at harvest on chernozem soil
Authors: Sárvári Mihály , Futó Zoltán 
Published: October 2019

In this paper, we analysed the results of maize sowing time experiments conducted by the Department of Crop Sciences and Applied Ecology of the University of Debrecen Agricultural Sciences Centre, during the period from 1997-1999. We made the experiments at the experimental garden of DE ATC, on a chernozem soil with lime deposits.In 1997, we examined five hybrids, in 1998 six hybrids, and in 1999 three hybrids, with three sowing times. Sowing times were early (10. Apr. and 08. Apr.), optimal (25. Apr. and 28. Apr.) and late (15. May and 17. May). We examined the following standards: yield, seed moisture content at harvest, thousand kernel mass, duration of flowering, emergence time and profitability.In 1977, the emergence times, in order of sowing, were: 24, 12 and 9 days. Yields of the sowing times were the following, in mean, for the five hybrids: in the early sowing time (10. Apr.) 11,81 t/ha, in the optimal sowing time (25. Apr.) 11,67 t/ha, and in the late sowing time (15. May) 12,9 t/ha. The seed moisture content of the five hybrids at harvest was 8% less in early sowing time, than in the late sowing time. The thousand kernel mass was the biggest in late sowing time, but we could not prove any significant connection attributable to the effect of sowing time. We examinedprofitability, too. Of the five hybrids, four attained the greatest profit with the early sowing time in 1997.In 1998, the emergence times, in the order of sowing, were: 21, 10 and 11 days. Yields of the sowing times were the following, in mean, for the six hybrids: 08. Apr. 10,34 t/ha, 25. Apr. 11,02 t/ha, 15. May 11,52 t/ha. There were no significant differences between yields in 1998. The seed moisture content of the six hybrids at harvest was 7% less for the early sowing time, than for the late sowing time. In 1998, the profits were greatest for theearly and traditional sowing times.In 1999, the numbers of days from sowing to emergence were 18, 9 and 9 days, in the order of sowing times. Yields of the sowing times were the following, in mean, for the three hybrids: 13,25 t/ha, 12,51 t/ha and 12,34 t/ha, in the order of sowing times. The seed moisture content of maizes at harvest was 6% less with an early sowing time in the mean of all hybrids. In 1999, hybrid maizes gave big profits with early sowing times.Summing up the results of the three years, we can conclude that we get a significant yield increase and reduced seed moisture content at harvest if we apply the early sowing time, which can considerably increase the efficiency of maize cultivation.
Cytokinin and auxin levels in micropropagating Red Fuji and McIntosh apple varieties
Authors: Magyarné Tábori Katalin , Dobránszki Judit , Ferenczy Antal , Jámborné Benczúr Erzsébet , Lazányi János 
Published: October 2019

Effects of media hormone content on in vitro shoot multiplication and rooting were examined in cv. Red Fuji and McIntosh apple scions. Multiplication responses of shoots to different concentrations (0.5 and 1.0 mg/l) of 6-benzylaminopurine and 6-benzylaminopurine riboside were tested at two levels (0.1 and 0.3 mg/l) of indole-3-butyric acid. The best proliferation rate was achieved on medium containing 1.0 mg/l 6-benzylaminopurine and 0.1 mg/l indole-3-butyric acid in cv. Red Fuji (5.3) and on medium containing 1.0 mg/l 6-benzylaminopurine and 0.3 mg/lindole-3-butyric acid in cv McIntosh (10.3). The length of shoots on these media was enough for rooting (38.4 mm in cv. Red Fuji and 39.3 mm in cv McIntosh). Shoots developed on the best proliferation medium were used for rooting. Effects of different concentrations of auxin in the root induction media and presence of activated charcoal in the root elongation media were examined on rooting capacity. The best rooting rate (100% in cv. McIntosh and 83% in cv. Red Fuji) was achieved when the root induction medium contained 1.0 mg/l indole-3-butyric acid. In general, rooting was inhibited in the presence of activated charcoal. Because of high in vitro multiplication and rooting rate and high percent of survival during acclimatisation, the methods described here make effective micropropagation processes possible for cv. Red Fuji and McIntosh.
Motivation in various agricultural organizations
Authors: Juhász Csilla 
Published: October 2019

As a PhD student I have studied the role of motivation within Hungarian agriculture among leaders of different levels and in several kind of organisations in order to find out the significance of various elements contributing to a motivated leaders and manpower.450 respondents were asked to describe their motivational situation by filling in a questionnaire.
Pecuniary rewards are the most important incitement to motivation within all categories of leaders followed by responsibility and result feedback. The possibility of punishment and job enrichment however, was not essential. Among limited corporation leaders result feedback and improvement of work conditions were the outmost source to motivation. Among cooperative leaders aim definitions and improvement of work condition were considered as the most important contribution to motivation. In their opinion punishment and job enrichment could not motivate.
‘Reinventing’ agricultural education for 2020 (action programme in the USA)
Authors: Juhász Csaba 
Published: October 2019

The world of agricultural education continues to grow more complex. We develop, disseminate and interpret more information in less time than ever before. These rapid changes require new ways of thinking, working and interacting. On January 1, 1996, in the United States of America, The National Council for Agricultural Education inaugurated „Reinventing Agricultural Education for the Year 2020” an initiative to strengthen agricultural and food systems education for the 21st Century. This project is a national effort on behalf of agricultural education, vision and strategic plan for agricultural education in the longer range future. „Reinventing Agricultural Education for the Year 2020” is a visionary planning initiative that brings together key stakeholders at the local, state, regional and national levels. These groups share their thoughts and ideas while developing concensus on what agricultural education should be in the 21st century.
Hubungan Lama Pemberian ASI dan Berat Lahir dengan Kejadian Stunting pada Balita di Wilayah Kerja Puskesmas Siulak Mukai Kabupaten Kerinci Tahun 2019
Authors: Angriani Selfi , Merita Merita , Aisah Aisah 
Published: October 2019

Kejadian stunting pada balita merupakan salah satu permasalahan gizi secara global. Prevalensi stunting di Kabupaten Kerinci tahun 2017 yaitu sebesar 35,0%. Tujuan penelitian ini adalah untuk mengetahui hubungan lama pemberian ASI dan berat lahir dengan kejadian stunting di wilayah kerja Puskesmas Siulak Mukai tahun 2019. Penelitian ini menggunakan desain cross sectional yang dilaksanakan di Wilayah Kerja Puskesmas Siulak Mukai pada bulan Mei tahun 2019. Populasi pada penelitian berjumlah 311 balita. Sampel pada penelitian yaitu 74 balita dengan teknik proporsional random sampling. Pengumpulan data menggunakan alat bantu kuesioner dan pengukuran status gizi menggunakan microtoise. Analisa data dilakukan secara univariat dan bivariat (chi-square test). Hasil penelitian menunjukkan bahwa sebagian besar memiliki status gizi normal (TB/U) (63,5%), lama pemberian ASI ≥2 tahun (67,6%), dan berat lahir ≥2500 gram (66,2%). Hasil analisa chi-square menunjukkan ada signifikan antara lama pemberian ASI dengan kejadian stunting (p=0,000), berat lahir dengan kejadian stunting (p=0,000). Oleh sebab itu, diharapkan kepada ibu balita untuk menerapkan ASI Ekslusif dan melanjutkan pemberian ASI hingga usia balita 2 tahun.
L’autisme, une clinique de l’extrême
Authors: Berger Frédérique F. 
Published: October 2019

Parmi les structures de la psychose, l’autisme est la forme la plus extrême des rapports du sujet au corps, au langage et à la parole. À partir des repères que nous assurent les enseignements de la psychanalyse nous soutenons l’existence d’un sujet au-delà des impossibles qui sont venus marquer son histoire. En étudiant la singularité de l’autisme et du sujet autiste nous allons approcher des questions théoriques et cliniques de grande importance tout en témoignant de notre pratique avec des enfants de différentes origines et cultures ; puis nous allons ouvrir des perspectives de réflexion concernant le traitement de l’autisme tout en interrogeant la pertinence de l’autisme comme quatrième structure clinique telle que la posent certains auteurs.
Honte et haine chez l’adolescente obèse
Authors: Sanahuja Maria de la Almudena , Maïdi Houari , Delostal Chloé 
Published: October 2019

Cet article propose d’aborder l’étiologie de l’obésité chez l’adolescente. La souffrance psychique qui en découle malgré l’amaigrissement. Chez le bébé, le regard maternel défini comme négatif et insécure induira au sein des relations précoces une carence d’étayage narcissique. Les effets de ce défaut fondamental d’étayage transparaîtront alors à l’adolescence par une altération de la perception de soi, tant au niveau du corps que du psychisme. Les deux narcissismes primaire et secondaire du sujet obèse resurgiront sur l’image inconsciente de son corps – image correspondant à son état somatique et son vécu intersubjectif –, produisant une image négative de lui-même. Nous montrerons, à l’aide d’un cas clinique paradigmatique, la manière dont « l’image du moi-corps » est troublée chez certaines adolescentes qui, malgré la perte de poids, continuent à se percevoir comme obèses et à entretenir la honte de soi et de leur corps.
Primo-socialisation culturelle par les climats familiaux des enfants de la cohorte Elfe
Authors: Berthomier Nathalie , Octobre Sylvie 
Published: October 2019

La primo-socialisation culturelle de l’enfant au sein de son foyer s’appuie sur trois piliers : les objets qui l’entourent, les interactions éducatives avec ses parents qui agissent par inculcation, et enfin les exemples parentaux qui fonctionnent par imprégnation. Le suivi de la cohorte Elfe constituée d’un panel de 18 000 enfants nés en 2011 permet d’observer comment ces trois logiques d’équipement, d’inculcation et d’imprégnation s’articulent selon les foyers. Les contextes de primo-socialisation sont plutôt d’abondance. Les enfants du panel Elfe grandissent dans des univers globalement bien dotés en équipements et produits culturels diversifiés (livres, disques, logiciels culturels ou éducatifs). À deux ans, les interactions culturelles des parents avec leur enfant sont répandues : les parents partagent plusieurs activités éducatives avec eux comme leur parler calmement, leur lire des livres d’histoire, dessiner ou encore regarder la télévision avec eux. Enfin, les enfants sont confrontés à des exemples parentaux d’engagement culturel puisque les parents des enfants de cette cohorte ont des consommations médiatiques, des usages numériques, de sortie et de fréquentation d’équipements culturels élevés. Dans ce contexte général d’abondance des dotations et d’intensité des engagements parentaux dans les activités culturelles, les facteurs de dotation ou de privation relèvent de choix éducatifs et de contraintes économiques. L’étude dégage cinq profils types de climats familiaux de primo-socialisation culturelle, qui articulent ces trois piliers de manière différente et affectent au père et à la mère des rôles spécifiques.
C'est quoi être mutualiste en 2020 ?
Authors: Bancel Jean-Louis 
Published: October 2019

Les coopératives financières, tout particulièrement dans le domaine de la banque et de l'assurance occupent une place significative du marché en Europe. Ces entreprises sont nées pour apporter des solutions de confiance et de solidarité à la masse des personnes impactées par la Révolution industrielle. Elles se sont adaptées aux évolutions chaotiques du xx e siècle. En accompagnant la constitution de la classe moyenne lors des Trente Glorieuses, elles ont poursuivi leur engagement de large répartition du progrès. Les défis qu'elles doivent affronter, au début du xxi e siècle, sont de savoir garder leurs spécificités dans un monde marqué par la course à la taille et surtout d'être les acteurs d'un humanisme en action face aux dangers de la réduction gestionnaire ou de l'imitation des opérateurs mus principalement par le seul profit financier. Classification JEL : G20, G32, L21, M14, N02, P13.