bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Rational Approach to a De-Escalation of Double Antithrombotic Therapy: The Possibilities of Clopidogrel
Authors: Kashtalap V. V. , Barbarash O. L. 
Published: October 2019

In the review based on existing clinical recommendations and guidelines of the European cardiology society and results of clinical and register trials difficult questions about a antithrombotic therapy in the patients with an acute coronary syndrome and percutaneous coronary interventions were discussed. The perspective strategy of risk management on ischemic and hemorrhagic events were described. Need of the maximum personification of purpose of double antithrombotic therapy at patients with an acute coronary syndrome or after carrying out transdermal coronary interventions is updated. Real requirement on constant assessment of balance in risks of ischemic and hemorrhagic events in this group of patients were defined. The perspective strategy of risk management in ischemic and hemorrhagic events from a position of results of relevant clinical trials were described. Results of clinical trials (TOPIC, TROPICAL-ACS) about transfer the ACS patients from “new” desaggregants on clopidogrel were presented (De-Escalation approach). Examples of the clinical situations suitable for realization of such approach were reviewed. The prospects of use of De-Escalation approach are designated and positions of a clopidogrel and, in particular, the original drug Plavix were provided. At the same time, appointment in patients with ACS within 12 months of double antiaggregant therapy is the proved option of treatment allowing to improve the prognisis. However, in some cases there is a reasonable requirement of the transfer of the patient from the “new” antiaggregants (ticagrelor or prasugrel) to clopidogrel (“de-escalation”). It needs to perfome according to the available evidence base recommendations and it is strict according to clinical indications. In particular, patients can have a perspective de-escalation with high risk of bleedings or with already developed bleeding; in patients with the forced refusal of reception of “new” antiaggregants owing to development of side effects / intolerance / allergic reactions; in the presence of indications for life long intake of anticoagulants in case of the need for purpose of double or triple antithrombotic therapy; in patients with ACS with low risk.
Response of melt water and rainfall runoff to climate change and their roles in controlling streamflow changes of the two upstream basins over the Tibetan Plateau
Authors: Zhang Yueguan , Hao Zhenchun , Xu Chong-Yu , Lai Xide 
Published: October 2019

AbstractLocated in the Tibetan Plateau, the upstream regions of the Mekong River (UM) and the Salween River (US) are very sensitive to climate change. The ‘VIC-glacier‘ model, which links a degree-day glacier algorithm with variable infiltration capacity (VIC) model, was employed and the model parameters were calibrated on observed streamflow, glacier mass balance and MODIS snowcover data. Results indicate that: (1) glacier-melt runoff exhibits a significant increase in both areas by the Mann–Kendall test. Snowmelt runoff shows an increasing trend in the UM, while the US is characterized by a decreasing tendency. In the UM, the snowmelt runoff peak shifts from June in the baseline period 1964–1990 to May for both the 1990s and 2000s; (2) rainfall runoff was considered as the first dominant factor driving changes of river discharge, which could be responsible for over 84% in total runoff trend over the two regions. The glacial runoff illustrates the secondary influence on the total runoff tendency; (3) although the hydrological regime is rain dominated in these two basins, the glacier compensation effect in these regions is obvious, especially in dry years.
Refronterización de la migración en tránsito por México. El caso de las migraciones centroamericanas por la Zona Metropolitana de Guadalajara
Authors: Hernández López Rafael Alonso , Porraz Gómez Iván Francisco , Morante Aguirre Mariana 
Published: October 2019

La creciente securitización y militarización de las políticas migratorias mexicanas en contra de la migración irregular ha dado pie a recientes refronterizaciones marcadas por el ensanchamiento y multiplicación de las fronteras a lo largo del territorio nacional, la consolidación de una “doble imaginación geográfica,” y los intentos de gubernamentalización de las migraciones en tránsito.
Enfocarse en regiones no tradicionalmente consideradas “zonas fronterizas”, resulta vital no sólo para entender el “carácter espacial del poder”, y de los procesos estatales, sino también para desmantelar los mecanismos que transforman a determinados sujetos en cuerpos “autorizados” y “no autorizados” para transitar, permanecer o ser reconocidos. En ese sentido buscamos una interpretación de las políticas espaciales (fronteras físicas y simbólicas) en la Zona Metropolitana de Guadalajara, México.
DETERMINATION OF SIMULTANEOUS IRBESARTAN AND HYDROCHLOROTHIAZIDE BY ULTRAVIOLET SPECTROPHOTOMETRY WITH DUAL WAVELENGTH METHOD
Authors: Syahputra Hafid , Muchlisyam M. Si. Apt , Masfria M.S. Apt 
Published: October 2019

Objective: The present study was aimed to develop a spectrophotometric method by dual wavelength method in simultaneous analysis of irbesartan and hydrochlorothiazide on tablet preparations without separation. Irbesartan and hydrochlorothiazide are a group of anti-hypertensive drugs that are very effective and safe to use to reduce blood pressure and edema. These drugs often given in combination with these active ingredients can cause problems in quantitative analysis for the quality control of preparations.
Methods: The study was carried out experimentally with a spectrophotometric method, one of which was dual wavelength method and then tested its validity based on validation parameters, namely linearity, accuracy, precision, LOD and LOQ and intraday and interday. Then, this method of irbesartan and hydrochlorothiazide in tablet preparations.
Results: The results of the study were showed that the application of dual wavelength method on the concentration was carried out at λ 263.4 nm and 281 nm for irbesartan and at λ 243.4 nm and 247.6 nm for hydrochlorothiazide. The results obtained by irbesartan and hydrochlorothiazide on tablets were (108.04 ± 2.696) and (94.28 ± 4.48)% respectively, and with good precision and accuracy.
Conclusions: The ultraviolet spectrophotometry method is dual wavelength method successfully applied for the determination of the concentration of irbesartan and hydrochlorothiazide in tablets.
BEST CO-APPROXIMATIONANDBESTSIMULTANEOUS CO-APPROXIMATION ININTUITIONISTIC FUZZY NORMED LINEARSPACES
Authors: Tarish Kadhim Bahlool , Mohammed Mohammed Jassim 
Published: October 2019

The main purpose of this paper is to study the t-best co-approximation and t-best simultaneous co-approximation in intuitionistic fuzzy normed spaces. We develop the theory of t-best co-approximation and t-best simultaneous co-approximation in quotient spaces. This new concept is employed by us to improve various characterisations of t-co-proximinal and t-co-Chebyshev sets .
THE f-NORM; A GENERALIZATION OF THE NORM OF FUNCTIONAL ANALYSIS
Authors: Sookoo Norris 
Published: October 2019

A generalisation, f-norm, of the concept of norm as defined in Functional Analysis is introduced. The norm of Î»x is |Î»|times the norm of x . In the definiton of the f-norm, this requirement is relaxed, so that the f-norm of Î»x is times the f-|Î»|norm of , where f is a function satisfying certain properties, which are presented. Examples of f-norms are given, the metric induced by an f-norm is considered and results concerning continuity of certain functions obtained. Sets that are convex with respect to an f-norm are studied. Limits with respect to the f-norm are also considered.
A method for local approximation of a planar deformation field
Authors: Ligas Marcin , Banaś Marek , Szafarczyk Anna 
Published: October 2019

Abstract
We present a method of approximation of a deformation field based on the local affine transformations constructed based on n nearest neighbors with respect to points of adopted grid. The local affine transformations are weighted by means of inverse distance squared between each grid point and observed points (nearest neighbors). This work uses a deformation gradient, although it is possible to use a displacement gradient instead – the two approaches are equivalent. To decompose the deformation gradient into components related to rigid motions (rotations, translations are excluded from the deformation gradient through differentiation process) and deformations, we used a polar decomposition and decomposition into a sum of symmetric and an anti-symmetric matrices (tensors). We discuss the results from both decompositions. Calibration of a local affine transformations model (i.e., number of nearest neighbors) is performed on observed points and is carried out in a cross-validation procedure. Verification of the method was conducted on simulated data-grids subjected to known (functionally generated) deformations, hence, known in every point of a study area.
City-region governance in transitional contexts: the case of the BRICS
Authors: Harrison Philip 
Published: October 2019

AbstractThe bulk of the scholarly literature on city-regions and their governance is drawn from contexts where economic and political systems have been stable over an extended period. However, many parts of the world, including all countries in the BRICS, have experienced far-reaching national transformations in the recent past in economic and/or political systems. The national transitions are complex, with a mix of continuity and rupture, while their translation into the scale of the city-region is often indirect. But, these transitions have been significant for the city-region, providing a period of opportunity and institutional fluidity. Studies of the BRICS show that outcomes of transitions are varied but that there are junctures of productive comparison including the ways in which the nature of the transitions create new path dependencies, and way in which interests across territorial scales soon consolidate, producing new rigidities in city-region governance.
PROJEKAT VIŠESPRATNE AB ZGRADE SPRATNOSTI Pr + 5 PREMA EVROPSKIM STANDARDIMA
Authors: Jovanović Dušan 
Published: October 2019

U prvom delu master rada je prikazan je projekat armiranobetonske zgrade spratnosti Pr+5, u drugom delu je prikazano poređenje kontrole probijanja ploča prema domačim (BAB ’87) i evropskim (Evrokod) propisima ploča direktno oslonjenih na stubovima.
POŽAR KAO KRIZNA SITUACIJA – ELABORAT ZAŠTITE OD POŽARA KOMPLEKSA HERTELENDI U BOČARU
Authors: Hadžibeti Diar , Pečujlija Mladen 
Published: October 2019

U radu je opisan sistem zaštite od požara u Kompleksu Hertelendi u Bočaru. U radu su, takođe prikazani rezultati potrebne količine vode za gašenje požara, koja se vrši iz hidrantske mreže. Takođe, vršena je podela objekata na požarne sektore kao i evakuacioni put u slučaju požara.
3D Human Pose Estimation in Vietnamese Traditional Martial Art Videos
Authors: Nguyen Tuong Thanh , Le Van-Hung , Duong Duy-Long , Pham Thanh-Cong , Le Dung 
Published: October 2019

Preserving, maintaining and teaching traditional martial arts are very important activities in social life. That helps preserve national culture, exercise and self-defense for practitioners. However, traditional martial arts have many different postures and activities of the body and body parts are diverse. The problem of estimating the actions of the human body still has many challenges, such as accuracy, obscurity, etc. In this paper, we survey several strong studies in the recent years for 3-D human pose estimation. Statistical tables have been compiled for years, typical results of these studies on the Human 3.6m dataset have been summarized. We also present a comparative study for 3-D human pose estimation based on the method that uses a single image. This study based on the methods that use the Convolutional Neural Network (CNN) for 2-D pose estimation, and then using 3-D pose library for mapping the 2-D results into the 3-D space. The CNNs model is trained on the benchmark datasets as MSCOCO Keypoints Challenge dataset [1], Human 3.6m [2], MPII dataset [3], LSP [4], [5], etc. We final publish the dataset of Vietnamese's traditional martial arts in Binh Dinh province for evaluating the 3-D human pose estimation. Quantitative results are presented and evaluated.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
PENGARUH KEPEMILIKAN MANAJERIAL, LEVERAGE, DAN PROFITABILITAS TERHADAP MANAJEMEN LABA
Authors: Manurung Elsya Manora , Isynuwardhana Deannes 
Published: October 2019

Earnings management can be defined as a deliberate intervention by management in determining the profit in the process of preparation of financial reporting, in order to gain personal profit. The existence cases earnings management not only the make the company concerned went bankrupt, but Also resulted in the perpetrators are punished as perpetrators of economic crimes, indication of earnings management by the news media that the capacity of the financial statements to report financial information to various parties become less relevant. This research aims is to analyze the effect factors that include ownership managerial, leverage and profitabilitas to earnings management.
This research methode uses is quantitative research method which is classified to causality verificative descriptive research. Population research is company mining sector registered at the indonesian stock exchange ( IDX ) periode 2013 to 2015, There are 24 mining companies included, and 72 data processed. Data process is taken from secondary data, Method analysis data is regression panel data using eviews program versi 8.0.
The result show that there are significant influence between managerial ownership, leverage and profitability with earning management either simultaneously. Partially, ownership managerial and leverage have no significant effect on earning management. While Probability has significant positif effect on earnings management
Pengaruh Pendapatan Asli Daerah (PAD), Dana Alokasi Umum (DAU), serta Belanja Modal terhadap Tingkat Kemandirian Keuangan Daerah Kabupaten/Kota Provinsi Jawa Barat
Authors: Nindita Nareswari Listya 
Published: October 2019

Penyelenggaraan pemerintahan yang diselenggarakan oleh daerah seluruhnya merupakan hak dan wewenang dan juga kewajiban daerah itu sendiri untuk mengatur jalannya pemerintahan daerah secara mandiri. Kemandirian keuangan daerah berarti pemerintah dapat melakukan sendiri dalam rangka asas desentralisasi. Tingkat kemandirian keuangan daerah dapat dilihat dari tingkat Pendapatan Asli Daerah, Dana Alokasi Umum, dan Belanja Modal yang dimiliki oleh daerah tersebut. Penelitian ini bertujuan untuk mengetahui bagaimana Pendapatan Asli Daerah, Dana Alokasi Umum, Belanja Modal dan Tingkat Kemandirian Keuangan Daerah Kabupaten/Kota Provinsi Jawa Barat Tahun 2014-2017 serta untuk mengetahui pengaruh parsial dan simultan diantara variabel tersebut. Sampel yang digunakan penelitian ini adalah 27 kabupaten/kota di Provinsi Jawa Barat dengan menggunakan metode sensus sampling atau sampling jenuh sehingga memperoleh 108 sampel.
Hasil penelitian ini menunjukan pendapatan asli daerah, dana alokasi umum, dan belanja modal berpengaruh secara simultan terhadap tingkat kemandirian keuangan daerah. Secara parsial, pendapatan asli daerah berpengaruh positif terhadap tingkat kemandirian keuangan daerah, dana alokasi umum tidak berpengaruh terhadap tingkat kemandirian keuangan daerah, belanja modal berpengaruh negatif terhadap tingkat kemandirian keuangan daerah.
Prevalence, risk factors and genetic characterisation of extended-spectrum beta-lactamase and carbapenemase-producing Enterobacteriaceae (ESBL-E and CPE): a community-based cross-sectional study, the Netherlands, 2014 to 2016
Authors: van den Bunt Gerrita , van Pelt Wilfrid , Hidalgo Laura , Scharringa Jelle , de Greeff Sabine C. , Schürch Anita C. , Mughini-Gras Lapo , Bonten Marc J.M. , Fluit Ad C. 
Published: October 2019

BackgroundThe epidemiology of carriage of extended-spectrum beta-lactamase-producing (ESBL-E) and carbapenemase-producing Enterobacteriaceae (CPE) in the general population is unknown.AimIn this observational study, the prevalence and risk factors for intestinal ESBL-E and CPE carriage in the Dutch general population were determined. ESBL-E were characterised.MethodsFrom 2014 to 2016, ca 2,000 residents were invited monthly to complete a questionnaire and provide a faecal sample, which was tested for ESBL-E. The first 1,758 samples were also tested for CPE. Risk factors for ESBL-E carriage were identified by multivariable logistic regression analysis. ESBL-E isolates underwent whole genome sequencing.ResultsOf 47,957 individuals invited, 4,177 (8.7%) completed the questionnaire and provided a faecal sample. ESBL-E were detected in 186 (4.5%) individuals, resulting in an adjusted prevalence of 5.0% (95% confidence interval (CI):3.4–6.6%). Risk factors were: born outside the Netherlands (odds ratio (OR): 1.99; 95% CI: 1.16−4.54), eating in restaurants > 20 times/year (OR: 1.70; 95% CI: 1.04−2.76), antibiotic use < 6 months ago (OR: 2.05; 95% CI: 1.05−4.03), swimming in sea/ocean < 12 months ago (OR: 1.63; 95% CI: 1.11−2.39), travelling to Africa (OR: 3.03; 95% CI: 1.23−7.46) or Asia (OR: 2.00; 95% CI: 1.02−3.90) < 12 months ago, and not changing kitchen towels daily (OR: 2.19; 95% CI: 1.24−3.87). The last had the largest population attributable risk (PAR) (47.5%). Eighty-four of 189 (44.4%) ESBL-E isolates carriedblaCTX-M-15.Escherichia coliisolates belonged to 70 different sequence types (ST)s, of which ST131 (42/178 isolates; 23.6%) was most prevalent. Associations were observed between IncFIA plasmids and ST131 andblaCTX-M-27, and between IncI1 and ST88 andblaCTX-M-1. No CPE were detected.ConclusionsThe prevalence of ESBL-E carriage in the Netherlands’ community-dwelling population is 5.0%. Identified risk factors were mostly travelling (particularly to Asia and Africa) and kitchen hygiene. CPE were not detected.
Las precipitaciones y los períodos húmedos en la Provincia del Chaco entre los años 1961 y 2005
Authors: Pyszczek Oscar Luis , Pérez María Emilia 
Published: October 2019

<p>Las precipitaciones constituyen el elemento del clima que presenta la mayor variabilidad espacio-temporal en sus registros y, a su vez, constituye un condicionante de gran importancia en el desarrollo de las actividades productivas. El presente trabajo pretende indagar acerca del comportamiento de las precipitaciones en la provincia del Chaco, determinando los períodos húmedos y las posibles variaciones significativas que se pudieron registrar en los mismos, durante el período 1961/2005. Para ello se analizaron datos pluviométricos mensuales provenientes de cinco estaciones meteorológicas, seleccionadas en función de la extensión de los registros y su localización en el territorio Provincial.</p><p> </p>
La perspectiva de género en la carrera de Geografía de la UNNE. Un esbozo de comparación con la incorporación del género a la ciencia geográfica
Authors: Falcón Vilma Lilian 
Published: October 2019

<p>El propósito de esta presentación es hacer una revisión de la incorporación de la teoría de género a la disciplina geográfica en general y de un modo más específico a la Geografía que se enseña e investiga a través de los planes de estudio del profesorado y licenciatura en Geografía de la Facultad de Humanidades de la Universidad Nacional del Nordeste (UNNE).</p><p>Una de las primeras reflexiones que considero relevante destacar es que la fuerte influencia de la corriente neopositivista en el diseño curricular de la carrera en geografía ha marcado, desde sus inicios a fines de la década del 50, una línea muy difícil de flexionar a tal punto que en los momentos actuales solo una ínfima parte de los programas curriculares del profesorado y licenciatura en Geografía exponen tímidamente temas relacionados con las “cuestiones de género”.<br />En este trabajo se expone brevemente el proceso que siguió la incorporación de la perspectiva de género en la ciencia geográfica y en un segundo momento se realiza un estado de situación de la Geografía académica que se ofrece en la región a través de nuestro profesorado y licenciatura en Geografía, destacando especialmente el período en que se llevó a cabo el proceso de cambio curricular realizado en el marco de la reforma educativa a fines de la década de los ’90 y la consecuente propuesta del Plan de Estudio 2000 actualmente vigente.<br />Como resultado de ese análisis surgen algunas consideraciones que destacan los avances logrados hasta el momento y fundamentalmente las cuestiones que aún están pendientes lograr para que el género comience a ocupar el nivel de categoría explicativa en nuestra propuesta curricular.</p><p> </p>
Las cooperativas en el contexto de las organizaciones de la economía social: breve reseña histórica. Características generales
Authors: Pertile Viviana Claudia 
Published: October 2019

<p>La Economía Social se constituye en una propuesta de una visión estructurada y coherente de múltiples actividades económicas y socio-económicas puesto que involucra una diversidad de factores en la que, las organizaciones del tercer sector juegan un rol importante en la producción total de bienes y servicios en la mayoría de las sociedades occidentales. El cooperativismo en Argentina se ha desarrollado en todas sus formas, respondiendo a diferentes momentos socio-económicos y problemas institucionales del país. A los efectos de indagar sobre esta temática se ha procedido al análisis de la bibliografía disponible sobre el cooperativismo y poder de ese modo reflexionar sobre el rol fundamental que estas desempeñaron en la estructura productiva nacional, regional y provincial.</p><p> </p>
Sistema de Información Geográfico para la prevención y alerta de incendios en el Noreste Argentino (NEA)
Authors: Cortez Ana María 
Published: October 2019

<p>Basado en la preservación de la biomasa, el equilibrio ecológico, la protección de vidas humanas y las situaciones trágicas de hechos relacionados tanto con la intervención del hombre como con causas naturales, se ha comenzado a desarrollar un sistema que permita evaluar los peligros de incendios forestales a fin de alertar en forma temprana y tomar las decisiones adecuadas en el manejo y control de los mismos.</p><p>Realizamos el Mapa Base (MB) con imágenes SAC-C georreferenciadas (capa raster) para el sustento de las distintas capas a desarrollar. El MB contiene todas las provincias que se encuentran comprendidas dentro del NEA, más una franja de un ancho a determinar por los expertos como zona de amortiguación de riesgo contra incendios que se inicien en las regiones adyacentes.</p>
Generación de un Sistema de Información Geográfica a partir de un CAD catastral
Authors: Romano Jorge R. , Molina Verónica G. 
Published: October 2019

<p><span>Se desea demostrar de que manera es posible la concepción de un Sistema de Información Geográfica (S.I.G.), en función de información pre-existente. Integrar todas las áreas del municipio y brindar, mediante una serie de insumos, información a dichas áreas. </span></p>