bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Influencing Intraoperative Rupture of Intracranial Aneurysms
Authors: Khadka Namrata , Rajbhandari Binod , Aryal Sameer , Bhattarai Sushil Mohan , Shrestha Rajendra , Jha Rajiv 
Published: December 2024

Introduction Intraoperative rupture (IOR) is the most anticipated yet dreaded complication during intracranial aneurysmal surgery, leading to severe adverse outcomes. This study aims to analyze various risk factors contributing to IOR.
MethodsIt was an analytical study of 46 cases of intracranial aneurysms treated at Department of Neurosurgery, Bir Hospital including both ruptured (n=43) and unruptured (n=3) aneurysms. Incidence of IOR, demographic data, preoperative grading scales, aneurysm morphology, phases and severity of IOR along with postoperative complications and outcomes were assessed.
ResultsIOR occurred in 28.26% (13/46) cases of intracranial aneurysms. Most common aneurysm was anterior communicating artery aneurysm (43.5%, 20/46) with majority of IOR (65.1%).Younger patients and males had higher rates of IOR, and early surgical intervention (within 72 hours) was associated with increased incidence (69.2%,9/13). Although preoperative factors showed no direct correlation with IOR, aneurysm size and morphology-dome width and height ratio (W/H) and irregular shapes of aneurysm emerged as critical risk factors (p<0.05). Temporary clipping during surgery appeared to reduce IOR, mostly mild (13.04%, 6/13) and occurred in second phase (17.39%; 8/13, during microdissection and neck preparation). However, IOR did not have adverse effects on postoperative complications and Glasgow Outcome Scale Extended (GOSE) at discharge.
ConclusionIncidence of IOR was 28.65%. Younger age, males, higher Fisher score, early timing of surgery of aneurysms and larger size increased the risk, while use of temporary clip reduced the risk. Dome H/W ratio and irregular shapes of aneurysm were important factors predicting IOR in this study.
Influencia del polvo de aluminio proveniente de materiales reciclables en las propiedades físicas y mecánicas de hormigones celulares
Authors: Rocha Argote Fernando 
Published: December 2024

En el rubro de la construcción elaborar materiales sustentables implica la reducción de aditivos que pueden contaminar el medio ambiente además de encarecer dichos materiales, de esta manera el objetivo de la presente investigación es evaluar la influencia de la incorporación del polvo de aluminio proveniente de materiales reciclables en las propiedades mecánicas del hormigón, mediante métodos experimentales por medio de las normas ASTM con la elaboración de 30 probetas cilíndricas y vigas de hormigón dosificados mediante el método ACI, donde se incorporó el polvo de aluminio en concentraciones de 10%, 25% y 50% respecto al peso del cemento, estos porcentajes fueron determinados a partir del peso específico del cemento. Los resultados obtenidos demuestran un decremento hasta del 5% en los valores del peso específico a partir de incorporar 25% de polvo de aluminio. El análisis ANOVA demuestra que no existe diferencia significativa entre la muestra de control y la muestra con incorporación del 10% de polvo de aluminio, es decir que la resistencia a compresión y flexo-tracción son similares en comparación a las muestras con 25% y 50% donde las resistencias disminuyen.
Современные биотехнологии в растениеводстве: достижения и тренды развития
Authors: А.Д. Темралеева 
Published: December 2024

Обзор посвящен основным современным технологиям растениеводства, направленным на получение высококачественных и экологически безопасных продуктов, а также на снижение потерь урожая и продуктивности, связанных с воздействием различных патогенов и вредителей. Обсуждаются преимущества и недостатки классической селекции, направленной на создание новых и улучшения существующих сортов растений преимущественно путем отбора и гибридизации, и генетическая модификация растений с конкретными примерами. Рассмотрены вопросы генетической паспортизации сельскохозяйственных культур, применения биоудобрений и биопестицидов, а также разработки эффективных тест-систем для диагностики их заболеваний.
The review is devoted to the basic cutting-edge crop production technologies aimed at obtaining high-quality and safe products, as well as the technologies able to reduce yield and productivity losses caused by pathogens and pests. The advantages and disadvantages of classical approaches to breeding plants, namely creation of new and improvement of the existing varieties through selection and hybridization, and genetic modification of plants are discussed. The genetic certification of agricultural crops, the use of biofertilizers and biopesticides, as well as the development of effective test systems for diagnosing plant diseases are considered.
Вязкость витрифицирующего раствора этиленгликоля в присутствии клатратообразующих газов Xe и Kr, измеренная методом динамического светорассеяния
Authors: Н.В. Пеньков , Н.Е. Крассова , Н.Э. Швирст , Е.Е. Фесенко 
Published: December 2024

Текущее состояние криобиологии характеризуется интенсивным развитием методов криоконсервации, основанных на витрификации (стекловании) водной фазы замораживаемого объекта. Одной из актуальных проблем является поиск путей снижения концентрации витрифицирующих агентов (криопротекторов), обеспечивающих стеклование, с целью минимизации токсического воздействия на замораживаемые клетки или ткани. В данной работе предложен новый экспериментальный подход, позволяющий повысить вязкость витрифицирующих растворов за счёт насыщения их инертными газами. В основе повышения вязкости лежит процесс гидратообразования, реализующийся при низких температурах и приводящий к переходу части воды в кристаллы газового гидрата. Снижение общего содержания воды в растворе приводит к концентрированию витрифицирующего агента и повышению вязкости. В работе экспериментально подтверждено увеличение вязкости 56,4 об.% водного раствора этиленгликоля, реализуемое в условиях повышенного давления Xe (9 атм.) и Kr (50 атм.) в диапазоне температур от -20 до -40°С. Для измерения вязкости под давлением при низких температурах впервые был адаптирован метод динамического светорассеяния.
The present state of the art in cryobiology is characterized by the intensive development of cryopreservation methods based on the vitrification of the aqueous phase. One of the actual problem is the search for pathways of decreasing the concentration of vitrification agents (cryoprotectants) to minimize the toxic effect on cells and tissues being frozen. In the present work, a new experimental approach has been developed that makes it possible to increase the viscosity of vitrification solutions by saturation with inert gases. An increase in viscosity is based on the hydrate formation, which occurs at low temperatures and leads to the transition of part of the water into the gas hydrate crystals. A decrease in the total content of water results in an increase in the concentration of the vitrification agent and, as a consequence, an increase in viscosity. The work experimentally confirms the increase in viscosity of a 56.4 vol.% aqueous solution of ethylene glycol, realized under conditions of increased pressure of Xe (9 atm.) and Kr (50 atm.) in the temperature range from -20 to -40°С. The viscosity under pressure was measured by the method of dynamic light scattering with some modifications.
The Impact of Artificial Intelligence (AI) and Digitalisation in Tourism Vocational Education
Authors: Aigbokhai Godwin , Bahcelerli Nesrin M , Akyurek Salim , Altinay Mehmet , Kenebayeva Ainur 
Published: December 2024

<p dir="ltr"><span>Artificial intelligence, digitalisation, and other variants of modern technology have been a central topics in the tourism sector in recent times. A bibliometric study investigated the impact of artificial intelligence and digitalisation in tourism education. a total of 1,911 published documents between years 2000 to 2023 were retrieved from the Scopus database. The study highlighted the evolving volume of studies on artificial intelligence applications in tourism education and the tourism sector by considering, authors and authorship networks, date of publications, countries, journal publications, citation count, research themes, keywords, and keyword co-occurrence. This evolution in the citation count and number of publications over the years is a pointer to the increasing attention on artificial intelligence generally and then on its role in tourism education and by extension tourism industry. Beyond the dates and citation count, the study reveals countries with the most publications in line with the theme of the study. To this end, China was shown to have more publications emanating from there. In terms of authorship, “Law Rob” and Ivanov Stanislav were shown to have made noteworthy contributions to the topic of consideration. The co-occurrence analysis carried out to identify key theme areas showed notable word cloud formation for terms such as “artificial intelligence”, “tourism” “education” “digitalisation” and “tourism industry”. The study concludes that more studies will be required in other to get the most out of the integration of artificial intelligence and digitalisation in tourism education.</span></p><div><span><br /></span></div>
How to Fix Global Warming With Cold Fusion
Authors: Rothwell Jed 
Published: December 2024

Cold fusion can eliminate the threat of global warming two ways: 1. Cold fusion does not produce carbon dioxide so if it replaces other sources of energy carbon emissions would stop. 2. Cold fusion can enhance the removal of carbon from the atmosphere by reforestation. Large scale reforestation projects have been proposed to remove carbon from the atmosphere and sequester it in trees. Cold fusion technology would greatly enhance such projects, increasing the amount of carbon by a factor of ten and reducing the cost of the project by a large factor. Cold fusion can be used to stop the natural boom and bust cycle of forest carbon, by burying charcoal made from deadwood underground. In effect this would speed up the formation of coal by a factor of a million. Conventional energy sources cannot do this.
A Self-Consistent Iterative Calculation for the Two Species of Charged Bosons Related to the Nuclear Reactions in Solids
Authors: Tsuchiya Ken-ichi 
Published: December 2024

Many theoretical studies on cold fusion have been done by many workers using Bose–Einstein condensation (BEC) in order to find a possible mechanism of this phenomenon. In our previous work on BEC approach to the theoretical interpretation of cold fusion, we estimated the transition temperature of BEC in palladium deuteride [1]. It was based on the Y.E.Kim’s work by using equivalent linear two-body (ELTB) method to the many-body problems of charged bosons trapped in an ion trap [2]. Recently, Kim et al. tried to explain the results of Rossi’s experiment [3] by using the ELTB method for a mixture of different two species of positive charged bosons trapped to the harmonic potential [4]. In this study, we verified Kim’s theory and considered how to perform the numerical calculation. A self-consistent iterative calculation was introduced and the coupled two equations corresponding to the two species of positive charged bosons were solved.
Phytochemical screening and in vitro antibacterial activity of Echinops kebericho Mesfin tuber extracts: experimental studies
Authors: Negasa Jiregna Gari , Teshome Ibsa , Sarba Edilu Jorga , Daro Bekiyad Shasho 
Published: December 2024

Background
The application of plant extracts and their phytochemicals as potential treatments for bacterial illnesses has increased significantly in the last few decades. In Ethiopia, Echinops kebericho Mesfin is widely used to treat a range of illnesses in humans and animals. This study aimed to evaluate the antibacterial activity and phytochemical screening of Echinops kebericho Mesfin.

Methods
We carried out an in vitro experimental study after collecting the plants from their natural habitats. Then macerated in absolute methanol and petroleum ether solvents and concentrated the extracts using a rotary evaporator. In the experiment, we used Standard cultures of E. coli, K. pneumoniae, S. aureus, and P. aeruginosa. The agar-well diffusion method evaluated the antibacterial activity of the plants. The agar dilution method determined the minimum inhibitory concentration of the plant extract.

Results
The percentage yield of the plant extracts ranged from 6.25% to 7.85%. The methanol extract of Echinops kebericho Mesfin had the highest inhibitory effect on S. aureus (ATCC 25923) (16.67 ± 0.58 mm), followed by E. coli (ATCC 25922) (11.0 ± 1.73 mm). Phytochemical screening of leaves from the methanol and petroleum ether extracts of the plant revealed the presence of phytochemicals such as alkaloids, flavonoids, tannins, and cardiac glycosides. The present study revealed that the extracts of these plants have antibacterial activity. However, researchers should conduct further studies on the safety margin and quantitative bioactive isolation of selected medicinal plants.
Study of Estimation of Hardness of Water Using pH-Meter
Authors: Mallick Abhijit 
Published: December 2024

The hardness of water is one of the important parameters of water quality. The complexometric titration method is a prevalent technique to estimate concentrations of and ions individually, which are primarily responsible for the hardness of water. However, the method needs two external indicators to mark the end points of titrations. Furthermore, accuracy of the method is sacrificed due to inevitable parallax errors during marking of the endpoint of titration.
This present work reports that during titration of a hard water sample with a complexing agent (here, solution), changes continuously. This change in is closely monitored and recorded graphically. Hence the endpoint of titration is determined. The neutralization volume, thus obtained, is used to estimate and hardness of the water sample separately. This novel technique obviates the use of any external indicators and eliminates any possible parallax error.
Biochemical characterization of archaeal homocitrate synthase from Sulfolobus acidocaldarius
Authors: Suzuki Tomohiro , Akiyama Nagisa , Yoshida Ayako , Tomita Takeo , Lassak Kerstin , Haurat Maria Florencia , Okada Takuya , Takahashi Kento , Albers Sonja‐Verena , Kuzuyama Tomohisa , Nishiyama Makoto 
Published: July 2019

The hyperthermophilic archaeon, Sulfolobus, synthesizes lysine via the α‐aminoadipate pathway; however, the gene encoding homocitrate synthase, the enzyme responsible for the first and committed step of the pathway, has not yet been identified. In the present study, we identified saci_1304 as the gene encoding a novel type of homocitrate synthase fused with a Regulation of Amino acid Metabolism (RAM) domain at the C terminus in Sulfolobus acidocaldarius. Enzymatic characterization revealed that Sulfolobus homocitrate synthase was inhibited by lysine; however, the mutant enzyme lacking the RAM domain was insensitive to inhibition by lysine. The present results indicated that the RAM domain is responsible for enzyme inhibition.
Evolution of Bioengineered Lung Models: Recent Advances and Challenges in Tissue Mimicry for Studying the Role of Mechanical Forces in Cell Biology
Authors: Doryab Ali , Tas Sinem , Taskin Mehmet Berat , Yang Lin , Hilgendorff Anne , Groll Jürgen , Wagner Darcy E. , Schmid Otmar 
Published: July 2019

AbstractMechanical stretch under both physiological (breathing) and pathophysiological (ventilator‐induced) conditions is known to significantly impact all cellular compartments in the lung, thereby playing a pivotal role in lung growth, regeneration and disease development. In order to evaluate the impact of mechanical forces on the cellular level, in vitro models using lung cells on stretchable membranes have been developed. Only recently have some of these cell‐stretching devices become suitable for air–liquid interface cell cultures, which is required to adequately model physiological conditions for the alveolar epithelium. To reach this goal, a multi‐functional membrane for cell growth balancing biophysical and mechanical properties is critical to mimic (patho)physiological conditions. In this review, i) the relevance of cyclic mechanical forces in lung biology is elucidated, ii) the physiological range for the key parameters of tissue stretch in the lung is described, and iii) the currently available in vitro cell‐stretching devices are discussed. After assessing various polymers, it is concluded that natural‐synthetic copolymers are promising candidates for suitable stretchable membranes used in cell‐stretching models. This work provides guidance on future developments in biomimetic in vitro models of the lung with the potential to function as a template for other organ models (e.g., skin, vessels).
Bioinspired Liposomes for Oral Delivery of Colistin to Combat Intracellular Infections by Salmonella enterica
Authors: Menina Sara , Eisenbeis Janina , Kamal Mohamed Ashraf M. , Koch Marcus , Bischoff Markus , Gordon Sarah , Loretz Brigitta , Lehr Claus‐Michael 
Published: July 2019

AbstractBacterial invasion into eukaryotic cells and the establishment of intracellular infection has proven to be an effective means of resisting antibiotic action, as anti‐infective agents commonly exhibit a poor permeability across the host cell membrane. Encapsulation of anti‐infectives into nanoscaled delivery systems, such as liposomes, is shown to result in an enhancement of intracellular delivery. The aim of the current work is, therefore, to formulate colistin, a poorly permeable anti‐infective, into liposomes suitable for oral delivery, and to functionalize these carriers with a bacteria‐derived invasive moiety to enhance their intracellular delivery. Different combinations of phospholipids and cholesterol are explored to optimize liposomal drug encapsulation and stability in biorelevant media. These liposomes are then surface‐functionalized with extracellular adherence protein (Eap), derived from Staphylococcus aureus. Treatment of HEp‐2 and Caco‐2 cells infected with Salmonella enterica using colistin‐containing, Eap‐functionalized liposomes resulted in a significant reduction of intracellular bacteria, in comparison to treatment with nonfunctionalized liposomes as well as colistin alone. This indicates that such bio‐invasive carriers are able to facilitate intracellular delivery of colistin, as necessary for intracellular anti‐infective activity. The developed Eap‐functionalized liposomes, therefore, present a promising strategy for improving the therapy of intracellular infections.
All 3D‐Printed Superhydrophobic/Oleophilic Membrane for Robotic Oil Recycling
Authors: Li Guijun , Mo Xiaoyong , Wang Yilin , Chan Ching‐Yuen , Chan Kang Cheung 
Published: July 2019

AbstractAdvanced materials with high oil recycling capability plays a crucial role in rescuing marine lives from oil spill catastrophe. The existing absorption and filtration method can partially solve the challenge; however, a highly recyclable, low energy cost, and environmentally friendly method for collecting oil on open water is still missing. Herein, a novel concept, using newly developed membrane for collecting oil, with surface tension confinement and gravity is proposed. Using a 3D‐printed superhydrophobic and oleophilic membrane, this self‐floating device can selectively collect oil on water surfaces. The device can be automatically driven by a robot and achieves outstanding reusability toward oil recycling. This novel chemical concept will enable future research development of oil–water separation and oil recycling.
Overcoming the Electroluminescence Efficiency Limitations in Quantum‐Dot Light‐Emitting Diodes
Authors: Khan Qasim , Subramanian Alagesan , Ahmed Imtiaz , Khan Maaz , Nathan Arokia , Wang Guoping , Wei Lei , Chen Jing , Zhang Yupeng , Bao Qiaoliang 
Published: July 2019

AbstractDevelopment of quantum dots (QDs) based light‐emitting diodes (QLEDs) is driven by attractive properties of these fluorophores such as precise Gaussian distribution, tunable emission, and facile solution processability. The performance of QLED devices is limited by intrinsic factors such as luminance quenching in quantum dots due to imbalanced carrier injection predominantly caused by a large hole injection barrier as well as by extrinsic processes such as nonradiative recombination at active layer interfaces. The Auger recombination problem is overcome by charge siphoning at the interfaces between QDs and charge‐transporting material. A simplest trilayer (p–i–n) LED structure is fabricated using an all‐solution processing method: a carefully engineered p‐type polymeric hole transport layer with a gradient work function is incorporated. The gradient work function creates the cascading energy levels from the moderate Fermi level anode to the deep‐lying valence band level of QDs. As a result, the QLEDs exhibit significantly improved external quantum efficiencies and luminous efficiencies of 15.9% and 31.8 cd A−1, 17.4% and 59.3 cd A−1, and 12.8% and 14.4 cd A−1 for red, green, and blue light‐emitting devices, respectively. It is expected that the concept demonstrated here will facilitate the design and development of efficient solution‐processible QLEDs for full‐color displays.
Superlithiophilic Amorphous SiO2–TiO2 Distributed into Porous Carbon Skeleton Enabling Uniform Lithium Deposition for Stable Lithium Metal Batteries
Authors: Xue Pan , Sun Chuang , Li Hongpeng , Liang Jiajie , Lai Chao 
Published: July 2019

AbstractLithium (Li) metal anodes have garnered increasing interest in recent years as its high theoretical capacity and low electrochemical potential promises a myriad of opportunities for various applications. However, one critical issue to overcome is the inhomogeneous deposition of Li+ during the plating and stripping process. This inhomogeneous deposition could result in uncontrollable dendrite growth, further leading to poor coulombic efficiency, shorter lifecycles, and safety concerns due to internal short circuit and thermal runaways. To address these issues, a 3D porous core–shell fiber scaffold is presented, comprising of well‐dispersed SiO2, TiO2, and carbon, as superlithiophilic host materials for lithium anodes. The amorphous SiO2 and TiO2 allow for controllable nucleation and deposition of metal Li inside the porous core–shell fiber even at ultrahigh current densities of 10 mA cm−2. In addition, the interconnected conductive fiber with high porosity enables good electrical conductivity with fast ion transport and excellent mechanical strength to withstand massive Li loading during repeated cycles of stripping and plating. As a result, excellent cycling performance and high rate capability are observed in both symmetric cells and full cells, highlighting the feasibility of the proposed Li anode composite.