bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Hubble Space Telescope PanCET Program: Exospheric Mg ii and Fe ii in the Near-ultraviolet Transmission Spectrum of WASP-121b Using Jitter Decorrelation
Authors: Sing David K. , Lavvas Panayotis , Ballester Gilda E. , Lecavelier des Etangs Alain , Marley Mark S. , Nikolov Nikolay , Ben-Jaffel Lotfi , Bourrier Vincent , Buchhave Lars A. , Deming Drake L. , Ehrenreich David , Mikal-Evans Thomas , Kataria Tiffany , Lewis Nikole K. , López-Morales Mercedes , García Muñoz Antonio , Henry Gregory W. , Sanz-Forcada Jorge , Spake Jessica J. , Wakeford Hannah R. ,   (The PanCET collaboration)
Published: August 2019

Abstract
We present Hubble Space Telescope (HST) near-ultraviolet (NUV) transits of the hot Jupiter WASP-121b, acquired as part of the PanCET program. Time-series spectra during two transit events were used to measure the transmission spectra between 2280 and 3070 Å at a resolution of 30,000. Using HST data from 61 Space Telescope Imaging Spectrograph visits, we show that data from HST’s Pointing Control System can be used to decorrelate the instrument systematic errors (jitter decorrelation), which we used to fit the WASP-121b light curves. The NUV spectra show very strong absorption features, with the NUV white light curve found to be larger than the average optical and near-infrared value at 6σ confidence. We identify and spectrally resolve absorption from the Mg ii doublet in the planetary exosphere at a 5.9σ confidence level. The Mg ii doublet is observed to reach altitudes of R
pl/R
star = 0.284 ± 0.037 for the 2796 Å line and 0.242 ± 0.0431 for the 2804 Å line, which exceeds the Roche lobe size as viewed in transit geometry (R
eqRL/R
star = 0.158). We also detect and resolve strong features of the Fe ii UV1 and UV2 multiplets, and observe the lines reaching altitudes of R
pl/R
star ≈ 0.3. At these high altitudes, the atmospheric Mg ii and Fe ii gas is not gravitationally bound to the planet, and these ionized species may be hydrodynamically escaping or could be magnetically confined. Refractory Mg and Fe atoms at high altitudes also indicate that these species are not trapped into condensate clouds at depth, which places constraints on the deep interior temperature.
Pattern of Impact-induced Ejecta from Granular Targets with Large Inclusions
Authors: Kadono Toshihiko , Suetsugu Ryo , Arakawa Dai , Kasagi Yoshiki , Nagayama Syuichi , Suzuki Ayako I. , Hasegawa Sunao 
Published: August 2019

Abstract
We performed impact experiments to observe patterns in an ejecta curtain with targets consisting of small sand particles and large inclusions comparable to or smaller than the size of the projectiles. The spatial intensity distributions in the ejecta at early stages of crater formation depend on the size of the inclusions. Our numerical simulations of radially spreading particles with different sizes support this result. Based on the results, we proposed a procedure for evaluating the subsurface structures of celestial bodies from the images of ejecta curtains obtained from space-impact experiments.
Record-breaking Coronal Magnetic Field in Solar Active Region 12673
Authors: Anfinogentov Sergey A. , Stupishin Alexey G. , Mysh’yakov Ivan I. , Fleishman Gregory D. 
Published: August 2019

Abstract
The strongest magnetic fields on the Sun are routinely detected at dark sunspots. The magnitude of the field is typically about 3000 G, with only a few exceptions that reported the magnetic field in excess of 5000 G. Given that the magnetic field decreases with height in the solar atmosphere, no coronal magnetic field above ∼2000 G has ever been reported. Here, we present imaging microwave observations of anomalously strong magnetic field of about 4000 G at the base of the corona in solar active region NOAA 12673 on 2017 September 6. Combining the photospheric vector measurements of the magnetic field and the coronal probing, we created and validated a nonlinear force-free field coronal model, with which we quantify the record-breaking coronal magnetic field at various coronal heights.
Longterm, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-based Registry
Authors: Harrold Leslie R. , Griffith Jenny , Zueger Patrick , Litman Heather J. , Gershenson Bernice , Islam Syed S. , Barr Christine J. , Guo Dianlin , Fay Jonathan , Greenberg Jeffrey D. 
Published: August 2019

Objective.To assess longterm safety in a US cohort of patients with rheumatoid arthritis (RA) treated with adalimumab (ADA) in real-world clinical care settings.Methods.This observational study analyzed the longterm incidence of safety outcomes among patients with RA initiating ADA, using data from the Corrona RA registry. Patients were adults (≥ 18 yrs) who initiated ADA treatment between January 2008 and June 2017, and who had at least 1 followup visit.Results.In total, 2798 ADA initiators were available for analysis, with a mean age of 54.5 years, 77% female, and mean disease duration of 8.3 years. Nearly half (48%) were biologic-naive, and 9% were using prednisone ≥ 10 mg at ADA initiation. The incidence rates per 100 person-years for serious infections, congestive heart failure requiring hospitalization, malignancy (excluding nonmelanoma skin cancer), and all-cause mortality were 1.86, 0.15, 0.64, and 0.33, respectively. The incidence of serious infections was higher in the first year of therapy (3.44, 95% CI 2.45–4.84) than in subsequent years, while other measured adverse effects did not vary substantially by duration of exposure. The median time to ADA discontinuation was 11 months, while the median time to first serious infection among those experiencing a serious infection event was 12 months.Conclusion.Analysis of longterm data from this prospective real-world registry demonstrated a safety profile consistent with previous studies in patients with RA. This analysis did not identify any new safety signals associated with ADA treatment and provides guidance for physicians prescribing ADA for extended periods.
On the shady side of economics
Authors: Van Heerden J. H. , Blignaut J. N. , Groenendijk N. S. 
Published: August 2019

This paper explains fraud from an economic point of view, using traditional economic tools and reasoning. It is shown how a supply-of-fraud function can be defined and estimated for individuals, and subsequently aggregated to derive crime rates for societies. Another approach is to explain the behaviour of fraudsters as rent-seekers, à la mode Gary Becker, and the problem of fraud may be seen as a case of market failure too. The paper also discusses some effects of fraud on society, and gives an empirical comparison between countries.
Adjuvant chemotherapy in stage II–III operated colon cancer patients from a nontrial cohort in a low colon cancer prevalence country with predominant use of modified CAPOX
Authors: Ramaswamy Anant , Kothari Rushabh , Desouza Ashwin , Gupta Tarachand , Bairwa Sandeep , Kapoor Akhil , Kumar Amit , Ventrapati Pradeep , Ramadwar Mukta , Mandavkar Sarika , Kumar Amit , Chavan Nita , Saklani Avanish , Ostwal Vikas 
Published: August 2019

Abstract
Background: Data regarding the practice of adjuvant chemotherapy, specifically with modified CAPOX, and survival outcomes in operated colon cancer patients from a nontrial cohort in a lower-middle income and low prevalence nation like India is scarce. Materials and Methods: Patients who underwent upfront curative resection for colon cancer from January 2013 to December 2016 were analyzed for baseline variables and outcomes. Results: A total of 491 patients underwent curative resection in the predefined time period. The median age of the patients was 53 years (range: 17–87). Patients with Stage I, Stage II, and Stage III disease comprised 7.9%, 44.8%, and 45.4% of the entire cohort, respectively. Patients with Stage I cancer were observed. Adjuvant chemotherapy was planned for 384 patients (78.2%), with the doublet regimens (capecitabine-oxaliplatin, or 5-fluorouracil-oxaliplatin) being used commonly (77.6%). Common toxicities were Hand-foot syndrome (Grade 2/3 - 21.4%) and peripheral neuropathy (Grade 2/3 - 20.1%). About 85% of patients receiving monotherapy (capecitabine or 5 fluorouracil) and 81.2% of patients receiving doublet chemotherapy (mCAPOX or modified FOLFOX-7) completed their planned adjuvant treatment. With a median follow-up of 22 months, estimated 3 years event-free survival was 86%, and overall survival (OS) was 93.6%. Stage, younger age (<50 years), underlying cardiovascular abnormalities, need for dose reductions and noncompletion of planned chemotherapy predicted for inferior estimated 3-year OS on multivariate analysis. Conclusions: Adjuvant chemotherapy especially with modified CAPOX appears well tolerated in the Indian population and early survival outcomes appear to be comparable to published literature.
Palliative chemotherapy in carcinoma nasopharynx
Authors: Patil Vijay M. , Joshi Amit , Noronha Vanita , Talreja Vikas , Simha Vijai , Dhumal Sachin , Bandekar Bhavesh , Chandrasekharan Arun , Prabhash Kumar 
Published: August 2019

Abstract
Introduction: Nasopharyngeal carcinoma is a rare malignancy. We conducted an audit of systemic therapies received in palliative setting in carcinoma nasopharynx and studied their outcomes. Methods: Patients who underwent first-line palliative systemic chemotherapy between January 2014 and April 2017 for carcinoma nasopharynx at the department of medical oncology at authors' institute were selected for this analysis. Toxicities, responses, progression-free survival (PFS), and overall survival (OS) were analyzed. In addition, a Quality-Adjusted Time without Symptoms or Toxicity analysis with threshold utility analysis was performed. Results: Fifty-one patients were included in this analysis. The indication of palliative chemotherapy was locoregionally recurrent disease in 25 (49.0%) patients and metastatic disease in 26 (51.0%) patients. The overall response rate was 62.0% (n = 33). The median PFS was 225 days (95% confidence interval [CI]: 164–274 days) and median OS was 513 days (95% CI: 286–931 days). The restricted mean TOX state duration was 2.6 days (95% CI: 0.3–4.9), restricted mean TWiST duration was 219.2 days (95% CI: 184.0–254.4), and restricted mean REL duration was 74.3 days (95% CI: 38.1–110.4). Conclusion: Systemic cytotoxic therapy in nasopharyngeal cancers is associated with high response rates and clinically meaningful PFS; with low duration of time spent in adverse events.
Patterns of brain metastasis in anaplastic lymphoma kinase - rearranged and epidermal growth factor receptor-mutated lung cancer patients in magnetic resonance imaging
Authors: Batra Ullas , Mahawar Vivek , Jajodia Ankush , Razdan Avinash , Mahanthi Himanshu , Koyyala Babu Venkata Pradeep 
Published: August 2019

Abstract
Introduction: The optimal management of neuroparenchymal lesions in cases of lung cancer is exigent as this frequent yet notorious complication negatively impacts the morbidity and mortality index. Aims: This study is aimed at recognizing various patterns of neuroparenchymal metastasis in patients of lung cancer with epidermal growth factor receptor (EGFR)- and anaplastic lymphoma kinase (ALK)-positive mutations. Material and Methods: The radiological findings of the neuroparenchymal lesions were analyzed and the statistical data were charted. We identified two groups of patients with neuroparenchymal lesions among a cohort of 340 patients having EGFR-positive (68) and ALK-positive (24) mutations (total: 24 + 68 = 92). Results: We observed that among the ALK group, leptomeningeal spread was less compared to EGFR group (2/24 as opposed to 18/68). Morphological heterogeneity and central necrosis in the parenchymal lesion which were associated with unfavorable outcomes were predominant in ALK group (8/24) as opposed to EGFR group (2/68). Ancillary findings but pertinent to survival and morbidity such as presence of perilesional edema, hemorrhage, and hydrocephalus on magnetic resonance imaging were also analyzed. The mutation-specific differential imaging spectrum could be attributed to biological differences between these cancers.
An analysis of implementation of Taguchi method to improve production of pulp on hydrapulper milling
Authors: Hernadewita Hernadewita , Rochmad I , Hendra Hendra , Hermiyetti Hermiyetti , Yuliani E.N.S. 
Published: August 2019

<div><p class="TtuloAbstract">Abstract: Taguchi method is one of a design of experimental (DOE), by using statistical approach to optimize the process parameters and maintaining the minimum variability and also improve the quality of product. Based on data characterisation, Nominal is Best in Taguchi methods is suitable application in this study. Its describe the procedures and steps that occur in DOE to find an optimum quality parameter corresponding quality characterisation. Nominal is the best applied in milling process of pulp on the hydrapulper with pulp freeness 650 Canadian Standard Freeness (CSF). The result is shown by orthogonal array, Signal-to-Noise (S/N) Ratio and analysis of variances (ANOVA). Three factors cosidered in this study and namely the composition of pulp (waste paper), pulp consistency and milling time. The experiment will conducted after determination of each level and the appropriate orthogonal array was selected. After measuring of pulp freeness produced by the pulp milling on the hydrapulper, then Signal-to-Noise (S/N) Ratio is calculated. As the conclussion, the factors and levels of optimum freeness obtained, pulp composition in level 1 (100%), pulp consistency at level 2 (8%) and milling time factor in level 2 (45 minutes). The result of experimental verification was interpreted in the conclusion.</p></div><p class="Abstract"><strong>Keywords:</strong> Taguchi; DOE; pulp; hydrapulper; Nominal is the Best; ANOVA</p>
Statement by The Managing Director on the Work Program of The Executive Board
Authors:   International Monetary Fund
Published: August 2019

This Work Program translates the strategic directions and policy priorities laid out in the Spring 2019 Global Policy Agenda and the International Monetary and Financial Committee Communiqué into an Executive Board agenda for the next twelve months. Its main policy priorities and related deliverables are as follows:

•	Support domestic policies to enhance resilience and inclusion:
•	Upgrade global cooperation to level the playing field and address other shared challenges
•	Adapt the Fund’s toolkits to lead and support change:
•	Continue to modernize the Fund to deliver for the future:
Two-dimensional hydrodynamic modelling of channel processes and floods characteristics at the confluence of the Amur and Zeya rivers
Authors: Fingert Eugeniya , Krylenko Inna , Belikov Vitaly , Golovlyov Pavel , Zavadskii Aleksandr , Samokhin Mikhail 
Published: August 2019

Abstract. Two-dimensional hydrodynamic STREAM_2D
model have been applied to the confluence of Amur and Zeya rivers. Main flow
characteristics and possible channel changes are considered during modeling
for two scenarios – without dams near Big Heihe Island (1) and with four
dams in the side channels around the island (2). Results of modeling
demonstrate impact of dams construction on flow concentrating in the main
channel, which can lead to increasing of flow velocities and subsequent
erosion in main Amur River channel downstream the river confluence.
“All That Is in the Settlement”
Authors: Neis Rachel Rafael 
Published: August 2019

Abstract
While biologists argue about the limits and definition of a species, the urge to cluster and distinguish among the plenitude of life-forms that populates the planet remains. Contemporary anxieties about attempts to clone monkeys and to engineer human-porcine chimeras point to concerns about species boundaries, resemblances, and causing suffering to other creatures. The fears about resemblances (and attendant slippery slope concerns) relate to how humans may be implicated. Such concerns about resemblances among kinds, the boundaries between species, and attempts to uphold distinctions, populated ancient zoological and anthropological thought, including that of the rabbis. While the rabbis drew on tselem elohim to theorize human reproduction and uniqueness, this article traces an alternative zoological vision that integrated humans among other kinds, while explaining resemblances among species with a theory of territorial doubles. This theory of territorial doubles claimed that all creatures—including humans—have versions that exist in the wild and in the sea.
La formación de los futuros docentes a través de la gamificación, tic y evaluación continua
Authors: Castañeda-Vázquez C. , Espejo-Garcés T. , Zurita-Ortega F. , Fernández-Revelles AB. 
Published: August 2019

El presente proyecto se ha llevado a cabo en el Grado de Educación Primaria, con el objetivo primordial de aumentar la motivación e implicación del alumnado a través del uso de estrategias de gamificación, TIC y evaluación continua en el aula. Para ello se desarrolló un proyecto de gamificación en el aula, a través de las TIC y la evaluación continua, el cual se desarrolla en este documento. Los resultados mostraron una alta participación del alumnado (más del 85% de los estudiantes participaron en el proyecto de gamificación). Casi el 95% de los estudiantes se presentaron a la evaluación en primera convocatoria, y el 87,9% del alumnado superó la asignatura en primera convocatoria. También se registraron altos niveles de motivación, tanto intrínseca como extrínseca, lo que supone una retroalimentación positiva para considerar esta innovación como una buena práctica educativa y seguir trabajando en cursos venideros con este tipo de metodologías.
This project was carried out Primary Education Degree. The main aim was to increase the students´ levels of motivation and involvement in the subject using gamification strategies, ICT and continuous assessment in the classroom. To this end, a gamification project was developed in the classroom, through ICT and continuous assessment, which is developed in this document. The results showed a high participation of the students (more than 85% of the students participated in the gamification project). Almost 95% of the students attended at the first final exam and 87.9% of the students passed the subject in first call. It was also observed high levels of students´ participation and involvement in the subject, as well as high levels of motivation, both intrinsic and extrinsic, which supposes a positive feedback to consider this innovation as a good educational practice and to continue working in future courses with this type of methodologies.
La influencia de 8 semanas de ejercicios aeróbicos, de fuerza y mixtos en el desempeño de la memoria a corto plazo de las mujeres
Authors: Delir A. , Mohammadi F. 
Published: August 2019

El propósito de este estudio fue investigar el efecto de 8 semanas de ejercicio aeróbico, de fuerza y mixto en el rendimiento de la memoria a corto plazo de las mujeres. Es un estudio cuasi experimental con un diseño pre / post test con tres grupos experimentales y un grupo control. Se seleccionaron 60 voluntarias, al azar, y se asignaron a cuatro grupos: grupo aeróbico, grupo de fuerza, grupo de fuerza aeróbica y grupo control. Todos los grupos realizaron sus protocolos de entrenamiento. La medición del rendimiento de la memoria a corto plazo se realizó mediante la prueba memory span en dos fases, antes y después de las sesiones de ejercicios. Los datos se analizaron usando la prueba de t de Student para muestras relacionadas y un análisis de la covarianza. Se utilizó el método de la diferencia menos significativa (LSD) para comparar grupos. Los resultados sugieren que 8 semanas de ejercicio aeróbico (p = 0,001), de fuerza (p = 0,001) y de fuerza aeróbica (0,029) aumentan el rendimiento de la memoria. Los resultados del análisis de la covarianza mostraron que 8 semanas de ejercicio aeróbico, de fuerza y de fuerza aeróbica afectan la memoria a corto plazo de las mujeres de manera diferente. Además, los resultados de la prueba de comparación de medias sugieren que existe una diferencia significativa entre los grupos de control, de fuerza aeróbica y de fuerza (p <0,05). Clínicamente hablando, estos hallazgos demuestran la importancia de los ejercicios aeróbicos, de fuerza, y de fuerza aeróbica para preservar y mejorar el rendimiento de la memoria.
The purpose of this study was to investigate the effect of 8 weeks of aerobic, strength and mixed exercise on short-term memory performance of women. It is a quasi-experimental study accomplished by a pre/posttest plan with three experimental groups and one control group. A total of 60 female volunteers were selected, randomly, allocated to four groups including: aerobic group, strength group, aerobic-strength group and control group. All the groups performed their training protocols. Measurement of short-term memory performance was done using memory span test in two steps pre and post of exercise sessions. Data was analyzed using dependent t-test and covariance test. Least significance difference (LSD) test was used to compare groups. The results suggest that 8 weeks of aerobic (p=0.001), strength (p=0.001) and strength-aerobic (0.029) exercise increases memory performance. The results of covariance test showed that 8 weeks of aerobic, strength and aerobic-strength exercise affect short-term memory of women differently. Also, the results of mean comparison test suggest that there is a significant difference between control, aerobic-strength and strength groups (p<0.05). Clinically speaking, these findings prove the importance of aerobic, strength, and aerobic-strength exercise in preserving and improving memory performance.
¿Cuáles son los factores que influyen en el proceso de identificación de talentos deportivos de Irán? Hallazgos de un estudio cualitativo
Authors: Kalani A. , Elahi A. , Nasrollah-Sajjadi S. , Zareian H. 
Published: August 2019

Este estudio tiene como objetivo determinar los factores que afectan el proceso de identificación del talento deportivo iraní. Teniendo en cuenta la naturaleza exploratoria del tema, se utilizó el método de investigación cualitativa y el enfoque de teorización basado en los datos. Primero, a través de los estudios iniciales y la revisión sistemática de los recursos relacionados, se identificó el inventario de signos efectivos. Posteriormente, se realizaron 23 entrevistas semiestructuradas dirigidas a expertos mediante el método de la bola de nieve. Las entrevistas continuaron hasta alcazar la saturación teórica. Los resultados de la codificación abierta indicaron que se extrajeron 145 signos primarios y 57 signos finales. En la codificación axial, los signos finales se clasificaron en 18 conceptos y 7 categorías principales. En consecuencia, se determinaron las categorías identificadas, incluidas las condiciones ambientales, las cuestiones individuales, culturales y sociales, la infraestructura, el sistema de gestión, la participación en los deportes y las partes interesadas clave. Los gerentes deportivos del país pueden usar los conceptos y categorías identificados para sus planes futuros con el fin de desarrollar la identificación del talento.
This study aimed to determine the factors affecting the process of Iranian sport talent identification. Considering the exploratory nature of the subject, the qualitative research method and the theorizing approach based on the data were used. First, through the initial studies and the systematic review of related resources, the inventory of effective signs was identified. Subsequently, 23 targeted semi-structured interviews with experts were conducted through snowball method. The interviews continued to reach the theoretical saturation. The open coding results indicated that 145 primary signs and 57 final signs were extracted. In the axial coding, the final signs were classified into 18 concepts and 7 main categories. Consequently, the identified categories including environmental conditions, individual, cultural, and social issues, infrastructure, management system, participation in sports, and key stakeholders were determined. The country sports managers can use the identified concepts and categories for their future plans in order to develop talent identification.