bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Food Insecurity in Recyclers from Waste Sorting Units in Southern Brazil
Authors: Soares Cássia Medino , Saueressig Camila , Alves Bruna , Beskow Carolina Bortolin , Filho Paulo Roberto Taborda de Souza , Joveleviths Dvora , Dall’Alba Valesca 
Published: July 2019

Abstract
Background

In areas of greater social vulnerability, there are high levels of food insecurity, infectious diseases and diseases secondary to malnutrition. However, in Brazil, there are few studies with recyclers from waste sorting units, resulting in a lack of health promotion programs for this population. This study aimed to describe the prevalence of food insecurity in recyclers from waste sorting units in the south of Brazil.

Methods

Cross-sectional study conducted from May of 2017 to April of 2018 with adult individuals from two waste sorting units in the city of Porto Alegre, southern Brazil. Clinical and nutritional evaluations were performed in the work environment, and three questionnaires were applied: the Brazilian Scale of Food Insecurity, the Alcohol, Smoking and Substance Involvement Screening Test, and the International Questionnaire of Physical Activity.

Results

One hundred and twenty-three subjects were evaluated, mean age 35 years, 66% female. A 74% rate of food insecurity was detected. About 57% of the participants presented overweight or obesity and 48% presented increased waist circumference.

Conclusion

Subjects presented high levels of Food Insecurity and immediate need of intervention for tobacco and alcohol abuse. There is a need for multidisciplinary interventions to prevent the situations found and the implementation of public policies addressing health promotion acts in the population of recyclers.
MASKED GENOTYPE 6 OF BOVINE LEUKEMIA VIRUS IS FOUND IN COLOMBIAN CATTLE
Authors: Corredor-Figueroa Adriana Patricia , Olaya-Galán Nury Nathalia , Salas Sandra Patricia , Quintero Juan Sebastián , Fajardo Álvaro , Soñora Martín , Moreno Pilar , Cristina Juan , Sánchez Alfredo , Tobón Julio , Ortiz Diego , Gutierrez María Fernanda 
Published: July 2019

Abstract
Background

Viral diseases such as bovine leukosis are a major cause of health problems associated with economic losses in the livestock industry worldwide. The prevalence of bovine leukosis ranges between 4% and 90%, and this disease is considered endemic. The etiological agent is bovine leukemia virus (BLV). Ten BLV genotypes have been reported based on analysis of complete or partial envelope gene sequences, of which genotype 1 is the most prevalent. However, the genetic variability of BLV variants circulating in Colombia remains unexplored. Therefore, in the present study, we analyzed blood samples collected from 289 cows distributed in 75 farms across the country. PCR amplification of env, gag and tax gene segments was performed. The obtained amplicons were sequenced and then subjected to phylogenetic analyses.

Results

A total of 62% of the cows present at 92% of the farms were BLV-positive. Genotype 1 was exclusively detected by env and gag gene segments when analyzed using previously reported primers. However, tax gene analysis revealed circulation of genotype 6 variants, which were also detected based on env gene analysis with newly designed primers. These results indicate that current genotyping approaches based on partial env sequencing may bias BLV genetic variability approaches and underestimate the diversity of the detected BLV genotypes.

Conclusions

This report is the first molecular and epidemiological study of BLV conducted in Colombia and contributes to the global epidemiology of the virus; it also reinforces the great impact of BLV on the country’s livestock and thus is a useful resource for farmers and government entities.
Safety and efficacy of en bloc transurethral resection versus conventional transurethral resection for primary nonmuscle-invasive bladder cancer：a meta-analysis
Authors: zhang dong , yao lifeng , yu sui , cheng yue , jiang junhui , ma qi , yan zejun 
Published: July 2019

Abstract
Abstract
Background: The purpose of this meta-analysis is to compare the safety and efficacy of en bloc transurethral resection of bladder tumor（EBRT） versus conventional transurethral resection of bladder tumor（CTURBT）.
Methods: We performed a meta-analysis of relevant articles through January 2019 using PubMed, Embase and Cochrane Central Register to compare the safety and efficacy of EBRT versus CTURBT. The main endpoint included the operation time（OT）, hospitalization time（HT）, catheterization time（AT），perioperative period complications, bladder detrusor muscle found in the specimen, the residual tumor on the base, the ratio of the same site recurrence and 12/24/36-month recurrence rate. Cochrane Collaboration’s Revman software, version 5.3, was used for statistical analysis.
Results: A total of 19 studies with 2651 patients were included，1369 underwent EBRT and 1282 underwent CTURBT. Patients treated with EBRT had a significantly lower AT, HT, obturator nerve reflex, bladder perforation, bladder irritation, postoperative complications and 24-month recurrence rate than those who underwent CTURBT. While no significant difference was found in terms of OT, the ratio of bladder detrusor muscle found in the specimen, the residual tumor on the base, 12-month recurrence rate, 36-month recurrence rate and the ratio of the same site recurrence. In mitomycin subgroup, EBRT was superior to CTURBT in terms of 12/24-month recurrence rate. Similarly, in the prospective subgroup and retrospective subgroup, EBRT had a lower 24-month recurrence rate than CTURBT. However, no significant difference was found in the low, intermediate and high-risk group in the light of 12-36 month recurrence rate.
Conclusions: Based on the included 19 articles, EBRT had a significantly lower AT, HT, intraoperative and postoperative complications and 24-month recurrence rate than those treated with CTURBT. Well designed randomized controlled trials were needed to reevaluate these outcomes.
Trial registration: This meta-analysis was reported in agreement with the PRISMA statement and was registered on PROSPERO 2019CRD42019121673.
Keywords: bladder tumor; en bloc transurethral resection; conventional transurethral resection of bladder tumor; meta-analysis; complication
Exploring an Energy Management Approach to Improve Fatigue and Life Participation in Adults on Chronic Dialysis
Authors: Farragher Janine F. , Polatajko Helene J. , McEwen Sara , Jassal Sarbjit V. 
Published: July 2019

Abstract
Background

Fatigue and its negative impact on life participation are top research priorities of people on chronic dialysis therapy. Energy management education is a fatigue management approach that teaches people to use practical strategies (e.g. prioritizing, using efficient body postures, organizing home environments) to manage their energy expenditure during everyday life. The study objective was to explore if energy management education is associated with improvements in fatigue and life participation in adults on chronic dialysis.

Methods

This study consisted of five single-case, interrupted time-series AB studies, and follow-up qualitative interviews. Participants on chronic dialysis therapy at an academic hospital in Toronto, Canada were purposively selected to represent diversity in age, gender and modality. All 5 participants underwent “The PEP Program”, a personalized, web-supported energy management education (EME) program designed to meet the needs of people on dialysis. During the program, participants complete two brief web modules about energy management, and then use energy management principles and a problem-solving framework to work on 3 life participation goals during sessions with a trained program administrator. Fatigue and life participation were measured weekly using short questionnaires during the baseline and intervention periods, and additional validated questionnaires (the Fatigue Impact Scale, SF36 Vitality Scale, & Canadian Occupational Performance Measure) were administered pre- and post-intervention. Data were analyzed using visual analysis and the Tau-U statistic for the weekly time-series data, and thematic analysis for the qualitative interviews.

Results

Three of five participants displayed a consistently positive response to the PEP program across multiple measures of fatigue and life participation. Tau-U effect size estimates ranged from small to moderate, according to the time-series data. All five participants expressed that the program had benefitted them in qualitative follow-up interviews, with the most common reported benefit being that the program made day-to-day activities easier. The format of the program was also said to be feasible and convenient.

Conclusions

The PEP program has potential to improve fatigue-related outcomes in people on chronic dialysis. Larger, controlled studies of the program are now warranted.
GANGGUAN KOGNITIF PADA EPILEPSI
Authors: Lukas Andre , Harsono Harsono , Astuti Astuti 
Published: July 2019

Epilepsi merupakan salah satu penyakit dalam bidang neurologi yang insidensi dan prevalensinya terus meningkat. Penurunan fungsi kognitif yang sering ditemukan pada epilepsi sangat bergantung pada beberapa faktor antara lain etiologi, tipe bangkitan, sindrom epilepsi tertentu (epilepsi idiopatik umum, epilepsi absans, juvenile myoclonic epilepsy, epilepsi lobus temporal, epilepsi lobus frontal, dll), letak lesi atau fokus bangkitan, frekuensi dan durasi bangkitan, umur saat onset, adanya gangguan psikis lain seperti kecemasan dan depresi, serta obat anti-epilepsi yang diminumnya.
Pada sebagian besar epilepsi, gangguan kognitif yang sering terjadi adalah gangguan pada atensi, psikomotor, visuospasial, memori dan fungsi eksekutif. Sindrom epilepsi tertentu seperti sindrom Ohtahara, West, Lennox Gastaut, CSWS (Continous Spike-Waves during Sleep Syndrome), dan Landau Kleffner Syndrome menunjukkan defisit kognitif yang lebih berat.
Manajemen epilepsi yang meliputi terapi farmakologis maupun terapi bedah berhubungan dengan munculnya gangguan kognitif pada penderita epilepsi. Walaupun obat anti-epilepsi generasi baru memiliki efek negatif terhadap fungsi kognitif yang lebih kecil dibandingkan dengan obat antiepilepsi generasi lama, namun penggunaannya termasuk dosis harus tetap hati-hati karena beberapa obat anti-epilepsi generasi baru juga berhubungan dengan penurunan fungsi kognitif yang nyata.
PENGARUH PEMBERIAN EKSTRAK CURCUMA LONGA DENGAN TINGKAT TOKSISITAS PARASETAMOL PADA GASTER, HEPAR DAN RENAL MENCIT JANTAN GALUR SWISS
Authors: Widagdo Cindy Tamara , Naibaho Pingkan , Jayadi Tejo , Danu Sulanto Saleh 
Published: July 2019

Latar Belakang: Curcuma longa dikatakan memiliki aktifitas hepatoprotektor, renoprotektor dan antiinflamasi terhadap dosis toksik parasetamol. Mengingat pemakaian jangka pendek dan jangka panjang, dan prevalensi toksisitas overdosis parasetamol semakin meningkat, perlu diteliti apakah Curcuma longa memproteksi kerusakan lambung, hepar dan renal sehingga dapat bersinergi dengan pengobatan overdosis parasetamol.
Metode Penelitian: Penelitian ini adalah eksperimental murni dengan rancangan acak lengkap (completely randomized design), menggunakan 36 ekor mencit jantan galur swiss. Dibagi 6 kelompok yaitu kontrol negatif, kontrol sham, kontrol positif, perlakuan satu, dua dan tiga. Tiga dosis ekstrak Curcuma longa terpurifikasi etil asetat 65 mg/kgBB, 487mg/kgBB dan 1040mg/kgBB diberikan selama 14 hari, dilanjutkan dosis tosik parasetamol 520 mg/kgBB selama 7 hari. Pemeriksaan serum SGOT, SGPT, ureum, kreatinin dan histopatologi lambung, hepar, renal untuk menilai apakah ekstrak Curcuma longa dapat memberikan proteksi kerusakan lambung, hepar dan renal dari akibat pemberian parasetamol dosis toksik.
Hasil dan Diskusi: Hasil pemeriksaan SGOT (p = 0,233), SGPT (p = 0,004), ureum (p = 0,19), kreatinin (p = 0,009) dan histopatologi lambung (p = 0,00), hepar (p = 0,00), dan renal (p = 0,00) menunjukkan ekstrak Curcuma longa terpurifikasi etil asetat memberikan efek toksik yang simultan dengan dosis toksik parasetamol. Efek toksik ini dapat dijelaskan karena bioaviabilitas curcumin dalam ekstrak Curcuma longa rendah sehingga pengaruh terhadap dosis toksik parasetamol dalam hepatosit diragukan, meningkatkan efek sitotoksisitas, dan menurunkan ekskresi metabolit toksik parasetamol.
Kesimpulan: Ekstrak Curcuma longa tidak memproteksi toksisitas terhadap gaster, hepar dan renal dari pemberian parasetamol dosis toksis pada mencit galur Swiss.
PATOFISIOLOGI TREMOR ISTIRAHAT PENYAKIT PARKINSON
Authors: Sukendar Komang Agus , Sutarni Sri , Subagya Subagya 
Published: July 2019

Tremor merupakan salah satu gerakan involunter yang paling sering
ditemukan. Tremor pada penyakit Parkinson menjadi gejala kardinal yang paling
membingungkan antara lain karena terpisah dari bradikinesia dan rigiditas, dapat
memberat pada sisi berlawanan dari sisi bradikinesia yang dominan (wrong-sided
tremor), penanda penyakit yang benigna, tidak berhubungan dengan banyaknya
defisiensi dopamin di substansia nigra, serta responsnya terhadap pengobatan
dopamin tidak sebaik gejala lainnya. Model klasik lebih menekankan peranan
ganglia basalis dalam memodulasi fungsi kortikal melalui sirkuit striato-thalamokortikal
yang mengalami disfungsi dan menyebabkan bradikinesia serta rigiditas,
namun tidak dapat menjelaskan tremor istirahat pada penyakit Parkinson.
Akan dikaji literatur tentang aspek patofisiologi tremor istirahat pada
penyakit Parkinson. Tremor dapat disebabkan oleh adanya osilasi mekanik pada
ekstremitas, refleks yang meningkat, osilasi sentral atau loop-feedback yang
abnormal dalam sistem saraf pusat. Osilasi tremor dapat terjadi pada level
membran neuronal, serta peningkatan eksitabilitas abnormal dan sinkronisasi
pada ganglia basalis yang mempengaruhi koneksi thalamus dan kortikalnya.
Dasar-dasar patofisiologi serta berbagai model hipotesis dengan strukturstruktur
yang terlibat telah dibuat untuk menjelaskan patofisiologi tremor
Parkinson. Kebanyakan model dibuat berdasarkan perekaman yang detail pada
sejumlah neuron yang terbatas misalnya preparat ex vivo, atau set bangunan yang
terbatas misalnya perekaman elektrofisiologi. Kebanyakan model berfokus pada
sebuah nodus pada sirkuit tunggal dan menginterpretasikan adanya perubahan
pada sirkuit lainnya sebagai akibat sekunder. Model hipotesis finger-switchdimmer
merupakan model hipotesis terbaru dan memberikan sebuah sudut
pandang level sistem, di mana tremor Parkinson diinduksi oleh aktivitas ganglia
basalis yang abnormal (finger), diproduksi oleh thalamus (switch), dan dimodulasi
atau diperkuat oleh serebelum (dimmer). Model ini dapat memberikan penjelasan
bagaimana sejumlah intervensi pada network ganglia basalis-thalamus dapat
menghilangkan tremor.
IMPLEMENTASI CLINICAL PATHWAY HERNIA INGUINALIS LATERALIS REPONIBILIS DEWASA DI RUMAH SAKIT BETHESDA YOGYAKARTA
Authors: Utami Yohana Puji Dyah , . Hariatmoko , Rasmiati Pudji Sri , Pinzon Rizaldy Taslim 
Published: July 2019

Pendahuluan: Permenkes 1438 tahun 2010 menetapkan standar
pelayanan kedokteran berupa Panduan Nasional Praktek Kedokteran (PNPK) dan
Standar Prosedur Operasional (SPO). SPO disusun dalam bentuk Panduan
Praktek Klinis (PPK) yang dilengkapi dengan alur klinis (Clinical Pathway).
Dipilihnya hernia untuk dibuat PPK/CP di RS Bethesda karena tingginya jumlah
kasus hernia yang dilakukan operasi. Tujuan dari penelitian ini adalah
membandingkan outcome pelayanan terkait hernia sebelum dan sesudah
implementasi Clinical Pathway.
Metode: Desain penelitian adalah quasi experimental after and before test.
Tempat pengambilan data adalah di RS Bethesda melalui dokumen dalam rekam
medis termasuk Clinical Pathway (CP). Waktu pengambilan data adalah sebelum
implementasi CP hernia dan setelah implementasi CP hernia. Populasi adalah
semua kasus hernia inguinalis lateralis reponibilis dewasa yang dilakukan
herniotomi sebelum implementasi PPK/CP dan setelah implementasi PPK/CP.
Hasil: Diperoleh sampel sebanyak 29 untuk pasien hernia sebelum
implementasi CP dan 29 setelah implementasi CP. Hasil menunjukkan persentase
kepatuhan sebelum dan sesudah implementasi CP pada penggunaan obat injeksi
meningkat (dari 44,82% menjadi 57,69%), pada penggunaan obat oral meningkat
(dari 20,08% menjadi 30,77%), pada penggunaan Spinal Anesthesia Block
meningkat (dari 17% menjadi 84,62%), pada penggunaan obat anestesi (dari 17%
menjadi 76,92%), pada lama rawat inap sebelum operasi kurang dari 24 jam
menurun (dari 93% menjadi 88,46%), dan pada lama rawat inap paska operasi
kurang dari 3 hari meningkat (dari 86% menjadi 88.46%). Rata-rata biaya rawat
inap sebelum dan sesudah implementasi CP pada kelas I sebesar Rp 8.050.350,00
dan Rp 8.231.700,00, pada kelas II sebesar Rp 6.668.580,00 dan Rp
6.139.733,00, dan pada kelas III sebesar Rp 4.542.100,00 dan Rp 4.464.400,00.
Kesimpulan: Clinical Pathway bermanfaat untuk memperbaiki indikator
proses pelayanan terkait hernia di RS Bethesda. Tidak ada perbedaan yang
bermakna dalam hal biaya pada implementasi CP hernia.
CITRA PEREMPUAN DALAM IKLAN KECAP DI MEDIA MASSA
Authors: Susiyanah Yuli 
Published: July 2019

<p>This article examines the image of women in soy sauce advertisements in the mass media. In general, the image of them in the mass media is depicted by stereotypes and patriarchal cultures inherent in them. They are generally described as agents of domestic roles and sex objects, who must be discriminated and subordinated. The theory used in this paper is gender relationship and mass media with qualitative content analysis. The theory is applied to analyze the positions between men and women in order to realize gender equality. Using qualitative content analysis, ABC soy sauce ads “true husbands want to cook” shows that there is a reconstruction concept of the relationship between men and women from a stereotypical and patriarchal culture to be a culture of gender equality. In this advertisement, the domestic job that is identified with the duty and responsibility of woman being able to be reconstructed into a role that can be performed by all people including men. It can shape public opinion about the image of women who must not be discriminated in the mass media.</p>
CYBERDAKWAH SEBAGAI FILTER PENYEBARAN HOAX
Authors: Mazaya Vyki 
Published: July 2019

<p>The internet has become an important part of the interactive communication of the Indonesian people. Information exchange is becoming faster with the advancement of information technology because everyone can easily access and share the information they receive. The ease of sharing information on the other hand can have a negative impact if it turns out that the information received is not clarified in advance. There needs to be an effort and awareness from internet users to prevent the spread of hoaxes on the internet, namely cyberdakwah. Cyberdakwah is an amar ma'ruf nahi munkar activity using internet media. Da'iof cyberdakwah needs to master information technology as one of the main weapons because the target of its dakwah is internet users. Da’i of cyberdakwah<br />also needs to understand netiquette (internet ethics) besides also having to understand the ethics of da'wahbased on Islamic teachings. This is because in exchanging information there are ethics and values that generally become a common agreement even though the rule may not be written.</p><p> </p>
Kota Layak Anak Berbasis Collaborative Governance
Authors: Duadji Noverman , Tresiana Novita 
Published: July 2019

<p>This paper describes the development of collaborative governance-based city/district, so it is hoped that children's policies and programs with holistic, integrative and sustainable character will be developed. This paper is the result of research aimed at: 1) mapping the problem and potential of children as central issue that can be developed as development issue; 2) develop an ideal city/district ideal child model. The research method used qualitative descriptive. Research location in Lampung Province. The results of the study describe children problems including child abuse, disability children, children faced with law and abandoned babies due to policies and programs that are not partial to children, policies are partially, segmentatively and sectorally arranged, no cooperation/partners with other institutions. The existence of local policy potential in the form of various policies and local regulations, the number of social institutions of children into social capital is strong physically and socially in building collaborative model/partnership. </p><p> </p>
SFAQUALI – fuzzy system for urban water quality assessment
Authors: Engelmann Juliana Tais , Frozza Rejane , da Costa Adilson Ben , Klamt Rodrigo Augusto 
Published: July 2019

Abstract
The objective of this study was to develop a system capable of evaluating the quality of the water consumed by an urban population using fuzzy logic. The set of factors to be analyzed were total coliforms, fluoride, free residual chlorine, turbidity, and apparent color. The factors selected as indicators of water quality and the system rules were modeled using the INFUZZY tool with help from specialists in this area, using a Great, Good, Acceptable or Inappropriate quality classification. 47 water quality analyses were applied. The results showed that 57.44% of the samples had a water quality classified as Great, 2.12% as Good, 2.12% as Acceptable, and 38.29% as Inappropriate. For each sample, results were in agreement with the evaluated parameters.
New Hemostatic Agents: Perioperative Anesthetic Considerations
Authors: Kietaibl Antonia-Therese , Kietaibl Sibylle 
Published: July 2019

Aim::Pharmacologic agents with procoagulant effects and antidotes against antithrombotic drugs play an important role in the prevention and management of perioperative coagulopathic bleeding. The aim of this narrative review is knowledge transfer from new and renewed hemostatic agents to anesthesiologists and other physicians involved in perioperative medicine.Methods::The literature search was performed on PubMed and the Summaries of Product Characteristics of 6 pharmacologic agents of interest: fibrinogen concentrate, vonicog alfa, susoctocog alfa, idarucizumab, andexanet alfa, and argatroban.Results and discussion: :This review highlights renewed interest in fibrinogen concentrate, an old prohemostatic drug, in correcting hypofibrinogenemia which is a leading pathomechanism of perioperative bleeding.:This review describes clinically relevant aspects for brand new recombinant prohemostatic drugs for their use in critical clinical situations: vonicog alfa for the prevention and correction of bleeding in von Willebrand syndrome, and susoctocog alfa in acquired hemophilia A.:Clinical experience and increasing evidence broadened the field of applications of the old antithrombotic drug argatroban to heparin resistance.:New antidotes against new antithrombotic agents revolutionized the safety of chronic antithrombotic therapy in the emergency situations of acute and trauma surgery.:Information on dosing and handling of new hemostatic drugs is summarized.Conclusion::New and potent hemostatic agents exist for perioperative use and may enrich the armamentarium of anesthesiologists. Implementation into clinical practice requires their availability and user knowledge. Sustainability of these new drugs depends on post-licensing research, cost-effectiveness, and clinical experience.