bluuebunny/crossref_metadata_2025_split huggingface dataset:
Online public response to emergency department diagnostic error report: A qualitative study
Authors: Sanford Timothy J. , Kaul Pranav , McCarthy Danielle M. 
Published: November 2024

AbstractBackgroundThe 2022 study on diagnostic error in the emergency department (ED) published by the Agency for Healthcare Research and Quality (AHRQ) reported that one in every 18 ED patients is misdiagnosed. The report was methodologically critiqued by emergency physicians and researchers. However, little is known about public perception of error in the ED. We sought to characterize public response to AHRQ's publication.MethodsA search was conducted for online news articles published December 2022 reporting the AHRQ study and containing “public comment” sections. Verbatim comments and relevant characteristics were collected. Three coders completed content analysis and resolved any differences. Descriptive statistics and themes are reported.ResultsFifteen online articles were reviewed; three had public comment sections (New York Times, DailyMail, and Boston Globe). There were 553 unique user comments; 293 were original comments (53%) and 260 were replies to comments (47%). The 260 replies were in response to 113 original comments, with the remaining original comments having 0 replies (n = 180). Of the 202 commenters who identified a personal role in a health care encounter, 70 (35%) identified as patients and 68 (34%) identified as physicians. Comments centered on seven major themes: (1) negative personal experiences, (2) reframing study conclusions, (3) sense of decline in training standards, (4) internal stressors impeding ED diagnostic accuracy, (5) external stressors impeding ED diagnostic accuracy, (6) suggested solutions, and (7) role of the ED in diagnosis.ConclusionsThe news coverage of AHRQ's report provided individuals a platform to share their perspectives. Many comments reflected a nuanced understanding of the role of emergency care and the stressors of the ED environment. Despite questions about the report's accuracy, there were many individuals who shared personal negative experiences suggesting that the public may feel directly impacted by error in the ED.
Self‐monitoring of the intraocular pressure with ICARE® HOME2 and a smartphone application: Feasibility and acceptability
Authors: Quérat Laurence , Chen Enping 
Published: November 2024

AbstractPurposeTo evaluate the feasibility and acceptability of self‐tonometry by glaucoma patients using iCare® Home2 (ICH2) and a smartphone application, without healthcare personnel supervision.MethodsAfter downloading a smartphone application, participants learned to handle the ICH2 via an instruction film, measured their intraocular pressure (IOP) and transferred the data to the caregiver via the application. Participants' measurements were compared to healthcare personnel measurements using Goldmann applanation tonometry (GAT). Participants answered questionnaires about their experience of self‐tonometry.ResultsTwenty‐eight participants were included in the study and three of them dropped off. There was no statistically significant difference between the last measurements obtained with ICH2 by the participants and the GAT measurements for the right and the left eye, p = 0.781 and p = 0.888 respectively. The inter‐user agreement was good to excellent between the last measurements obtained with ICH2 by the participants and the GAT measurements for the right and the left eye (ICC 0.907 and 0.830 respectively). The overall impression of the participants was very positive, with 92% happy (a lot or completely) with the instruction film and 88% happy (a lot or completely) with the smartphone application. Thirty‐six percent would have preferred to have an instructor by their side.ConclusionOur study showed the feasibility and acceptability of self‐tonometry with iCare® Home2 and a smartphone application without the supervision of a healthcare provider in a group of motivated glaucoma patients.
Sowing the seeds of love: Cultivating perceptions of culture of companionate love through listening and its effects on organizational outcomes
Authors: Itzchakov Guy , Barsade Sigal , Cheshin Arik 
Published: November 2024

AbstractFostering a culture of companionate love in the workplace offers numerous benefits for employees, yet the methods for achieving this remain unclear. We propose that high‐quality listening, characterized by undivided attention, understanding, and a positive and non‐judgmental intention toward the speaker, could be a key facilitator. We hypothesized that such listening could enhance employees' perceptions of companionate love. Additionally, we hypothesized that an enhanced perception of companionate love would increase employees' subjective well‐being, resilience, affective commitment, and willingness to cooperate at work. To examine these hypotheses, we conducted four studies. Study 1 was a preregistered and highly‐powered field study (N = 752) involving employees from various organizations. Study 2 (N = 37), was a longitudinal research that included a listening training of 16 hours for teachers in a single school. Study 3 was a quasi‐field experiment within a risk‐management company, with employees receiving 12 hours of listening education while a waitlist served as a control group (N = 67). Study 4 was a quasi‐experiment that served as a conceptual replication and extension of Studies 2 and 3. The study involved listening training for employees in a global communications company, providing 14 hours of online listening training. An active control group (N = 60) was included. Across all studies, we found that feeling listened to by colleagues led to increased perceptions of companionate love in the organization, which, in turn, increased employees' subjective well‐being, resilience, affective organizational commitment, and willingness to collaborate. Theoretical and practical implications are discussed.
Dual effects of DLG5 (disks large homolog 5 gene) modulation on chemotherapy‐induced thrombocytopenia and nausea/vomiting via the hippo signalling pathway
Authors: Li Mingming , Wang Rong , Yan Tao , Tao Xia , Gao Shouhong , Wang Zhipeng , Chai Yunsheng , Qiu Shi , Chen Wansheng 
Published: November 2024

AbstractBackground and PurposeThe CAPEOX (combination of oxaliplatin and capecitabine) chemotherapy protocol is widely used for colorectal cancer treatment, but it can lead to chemotherapy‐induced adverse effects (CRAEs).Experimental ApproachTo uncover the mechanisms and potential biomarkers for CRAE susceptibility, we performed whole‐genome sequencing on normal colorectal tissue (CRT) before adjuvant chemotherapy. This is followed by in vivo and in vitro verifications for selected gene and CRAE pair.Key ResultsOur analysis revealed specific germline mutations linked to Grade 2 (or higher) chemotherapy‐induced thrombocytopenia (CIT) and nausea/vomiting (CINV). Notably, both CRAEs were associated with mutations in the DLG5 gene. We found that DLG5 mutations related to CIT were associated with increased gene expression, while those associated with CINV were linked to suppressed gene expression, as indicated by the Genotype‐Tissue Expression (GTEX) database. In megakaryocytes, overexpression of human DLG5 suppressed the hippo signalling pathway and induced YAP expression. In zebrafish, overexpression of human DLG5 not only reduced platelet production but also inhibited thrombus formation. Subsequent qPCR analysis revealed that DLG5 overexpression affected genes involved in cytoskeleton formation and alpha‐granule formation, which could impact the normal generation of proplatelets.Conclusion and ImplicationsWe identified a series of germline mutations associated with susceptibility to CIT and CINV. Of particular interest, we demonstrated that induced and suppressed DLG5 expression is respectively related to CIT and CINV. These findings shed light on the involvement of the hippo signalling pathway and DLG5 in the development of CRAEs, providing valuable insights into potential targets for therapeutic interventions.
Audio description for all? The benefits and concerns of extending access provision to sighted people
Authors: Adams Ellen 
Published: November 2024

AbstractAudio description (AD) is an established part of museums' access programs for blind and partially blind (BPB) people. This paper explores the merits and caveats regarding “AD for all”, rolling out the provision for sighted people as well. It draws from four separate Access All Senses (AAS) events in three different London museums, each conducted under slightly different conditions. In addition to collecting nearly 100 audience feedback forms, this study has involved museum access staff, audio describers, and BPB art lovers. These events demonstrate that there is a demand among sighted people to include AD in museum tours as “guided looking”. The main concern regards the unintended consequences that could threaten the specific provision that BPB people need. A brief survey at the end offers examples of museum initiatives where AD is being rolled out while protecting these interests.
Engagement in Extracurricular Activities: Does It Matter to Consider Students' Sense of School Belonging?
Authors: Hoang Le Nguyen 
Published: November 2024

ABSTRACTThis research aims to analyse the complex connections between students' engagement in extracurricular activities (ECAs), their sense of school belonging, and the cumulative effects on their psychological well‐being and academic performance. The results based on a sample of 892 students reveal that active engagement in ECAs does not influence students' academic outcomes directly. Instead, the benefits derived from ECAs primarily manifest in non‐academic spheres, particularly in enhancing well‐being. Moreover, ECAs yield positive psychological well‐being and academic performance only when students have a low sense of school belonging. At higher levels, the positive impact of ECAs diminishes, and it may even detrimentally affect academic performance. This study offers a different viewpoint to address the dilemma surrounding ECAs and practical implications in the development of institutional policies.
“Discover your potential to raise your children”: A psychoeducational infancy parenting intervention in Spain
Authors: Arranz‐Freijo Enrique B. , Barreto‐Zarza Florencia , de Lahidalga Aitziber Martínez , Tomás‐Llerena Clementina , Macía‐Guerrero Patricia , Garcia‐Elburgo Susana , Sánchez‐Pinedo Silvia 
Published: November 2024

AbstractBackgroundThe quality of parenting has a significant impact on healthy development across the life cycle. Recent research has highlighted the financial return of evidence‐based parenting programs that are well designed and implemented.ObjectiveTo analyze the impact of a psychoeducational guidance intervention program aimed at improving parenting skills.MethodThirty‐five families with children aged between 0 and 3.5 years referred from the educational, social, and health departments of the Vitoria‐Gasteiz City Council (Spain) participated in the study. Using a longitudinal approach, the intervention took place over the course of three home visits: initial pretest assessment visit, feedback and orientation visit, and a final posttest assessment visit.ResultsStatistically significant pretest–posttest differences were observed in parenting skills, including cognitive and socio‐emotional development scaffolding, parental self‐efficacy, parental adaptive stress, and diversity of experiences.ConclusionsSeveral areas for improvement were detected in the context of an intervention based on customized guidance for individual families. The implementation process indicated issues to be improved in future program editions.ImplicationsOur findings provide family and public health policy makers with empirical support for the implementation of parenting programs designed to help families to acquire and improve parenting competencies to foster their children's comprehensive development, focused on the period between 0 and 3.5 years of life. Results of the study favor the propagation among Spanish professionals who work with families of the use of quality standards of the evidence‐based approach related to quality of implementation and assessment of the impact of parenting programs.
Dental Hygienists' Influence on Oral Health Knowledge, Attitudes and Behavioural of Patients and Effectiveness on Improving Patients' Periodontal Status—Evaluations of a Hospital Based Oral Hygiene Training Program in China
Authors: Yang Aijuan , Yuan Wenlin , Yang Lili , Lei Lihong , Cao Zheng , Chen Lili 
Published: November 2024

ABSTRACTObjectivesTo evaluate the possibility of integrating dental hygienists (DHs) into the dental field in China, and investigate its effectiveness on improving patients' knowledge, attitudes, self‐care behaviours as well as their periodontal status.MethodsA hospital‐based oral hygiene training program was developed at Sir Run Run Shaw Hospital's (SRRSH) Dental Clinic with the support of two registered DHs from Loma Linda University in California. A questionnaire evaluating oral health knowledge, attitudes and behaviours was conducted in patients who visited SRRSH's Dental Clinic. Scores of oral health knowledge and proportions of positive oral health attitudes and favourable self‐care behaviours were estimated between patients treated and not treated by DHs (DH group and NDH group). The improvements in patients' periodontal conditions following non‐surgical periodontal therapy (NSPT) administered by DHs at the Dental Clinic of SRRSH, as assessed through the measurement of periodontal pocket depths and the incidence of bleeding upon probing.ResultsPatients in DH group exhibited relatively better results in several aspects of oral health knowledge, attitudes and behaviours, compared to those in NDH group. Moreover, NPST performed by DHs significantly improved the periodontal status of the patients, with a remarkably reduction in periodontal pocket depth and bleeding on probing.ConclusionsIntegrating DHs into SRRSH's Dental Clinic showed effectiveness in enhancing patients' oral health knowledge, attitudes, behaviours and succeeded in improving patients' periodontal status. This program demonstrated that incorporating DHs into dental care team is not only practical but also enhances the value of the dental workforce in China.
Effect of Different Concentrations of Chlorhexidine on Anti‐Plaque in Oral Care Practice: A Systematic Review and Network Meta‐Analysis
Authors: Liang Shiqi , He Yirong , Chen Xinrong , Wu Menghang , Li Ka 
Published: November 2024

ABSTRACTObjectivesThe aim of this network meta‐analysis was to compare the anti‐plaque effects and adverse effects of different concentrations of chlorhexidine (CHX).MethodsPubMed, OVID Embase and the Cochrane Library were searched from inception to October 2023 for randomised controlled trials (RCTs) of different concentrations of CHX in healthy populations. Random‐effects network meta‐analyses were performed to summarise the evidence, and the Grading of Recommendations Assessment, Development and Evaluation framework was used to rate the certainty of evidence. Cohen's d standardised mean differences were calculated as the measure of effect size.ResultsThirty‐eight RCTs involving 2011 participants and six concentrations of CHX (0.2%, 0.12%, 0.1%, 0.3%, 1% and 0.06%) were included. The anti‐plaque effects of CHX at all concentrations were compared with placebo. Moderate to very low certainty evidence established 0.2% CHX as the most effective on anti‐plaque. 0.12% and 0.1% CHX also showed significant anti‐plaque effects. However, the ranking probabilities showed that the adverse effects of 0.12% and 0.1% CHX were < 0.2% CHX.ConclusionsCompared with placebo, 0.2%, 0.12% and 0.1% CHX had significant anti‐plaque effects, with moderate to very low certainty evidence that 0.2% CHX was most effective on anti‐plaque. However, 0.2% CHX had larger adverse effects than 0.12% and 0.1% CHX.Trial RegistrationPROSPERO: Number CRD: 42022327083
Immobilization of arsenic wastes and retardation effect on cement hydration: Experimental and molecular dynamic analysis
Authors: Chen Yuting , Yuan Qiang , Zhu Zheyu , Xu Linglin , Sun Zixuan , Xue Lingli , Wu Kai 
Published: November 2024

AbstractThis work was designed to investigate the influence of arsenic dosage, variety on the mechanical properties, hydration, and solidification from the perspective of Portland cement (PC) performance evolution. The results demonstrate that using PC could solidify the arsenic wastes effectively, with arsenic leaching concentrations consistently below 5 mg/L. Arsenic wastes retard cement hydration, leading to a slower rate of hydrates formation, disrupting the calcium silicate hydrate (C–S–H) stacking structure, and thus detrimental to strength development especially at early age. The adverse effect is highly dependent on the arsenic variety. The insoluble calcium arsenate exhibits the least impact, while the arsenates show the largest challenging to immobilization due to the instability of hydrates. Molecular dynamic simulation indicates that arsenic can be chemically immobilized with Ca2+, and be physically adsorbed onto the positively charged C–S–H by forming As‐O···Ca···Si‐O units, accompanied by a significant reduction in adsorption energy by 46.5%. The arsenic solidification behavior provides a basis for the resource utilization of arsenic wastes in cementitious materials.
The Relationship Between Social Media Addiction and Perceived Stress in Adolescents
Authors: Sarialioğlu Arzu , Oluç Tuğba 
Published: November 2024

ABSTRACTPurposeThe study was conducted to determine the relationship between social media addiction and perceived stress in adolescents.MethodThe study was conducted in a descriptive and cross‐sectional design between September and December 2022 in secondary education institutions of the Provincial Directorate of National Education in a city center in eastern Turkey. The sample of the study consisted of a total of 716 adolescents who were studying in the ninth grade (145), 10th grade (198), 11th grade (216), and 12th grade (157) who met the inclusion criteria of the study at the time the study was conducted. The sample comprised individuals with diverse sociodemographic characteristics, including ages, genders, school success levels, parents’ education levels, parents’ job status, socioeconomic status, time spent on daily social media, and purposes of social media use of the adolescents. The “Sociodemographic Characteristics Form,” “Social Media Addiction Scale for Adolescents (SMASA),” and “Perceived Stress Scale (PSS)” were used as the data collection tools. Ethical principles were fulfilled in the study.ResultsIt was found that the average age of the adolescents who participated in the study was 15.71 ± 1.22, 58.1% were females, 41.1% had good school success, 90.5% had a mobile phone, 90.2% used WhatsApp, 56.8% said that their daily social media use time was between 1 and 3 h, and 64% said that their purpose of using social media was for entertainment and leisure. The mean SMASA score was 18.49 ± 6.98, and the mean PSS score was 42.11 ± 7.54. It was found in the study that the mother's employment status, phone ownership status, use of Instagram, Facebook, Twitter, WhatsApp, Snapchat, YouTube, TikTok, and LinkedIn accounts, daily social media use, time and purposes of using social media affected the mean SMASA score. Age, gender, school success, use of Instagram and Snapchat accounts, daily social media use time, and purposes of using social media affected the mean PSS score (p < 0.05). As a result of the study, a positive and low‐level significant relationship was detected between social media addiction and perceived stress levels (p < 0.01).ConclusionAs the levels of social media addiction increase in adolescents, the perceived stress levels also increase. It was also found that some variables affected the social media addiction and perceived stress levels of adolescents.
A sensitivity analysis of the Earth for all model: Getting the giant leap scenario with fewer policies
Authors: Crescenzi Pierluigi , Gambosi Giorgio , Nasti Lucia , Rossi Aurora , Natale Emanuele 
Published: November 2024

AbstractIntegrated assessment models (IAMs) are popular tools used to predict the evolution of human society, a challenging question that science has long tried to address. The World3 model is a popular IAM, designed in the seventies by several scientists convened by the Club of Rome and mostly known for its usage to analyze the so‐called limits to growth. The recent Earth for all (E4A) model has been initiated by one of the major co‐authors of the World3 model, Jørgen Randers. It is substantially more complicated than the relatively simple World3 model, and it has been used to compare two different and opposite world development scenarios: the too little too late scenario, in which current policies are assumed to continue, and the giant leap (GL) scenario, in which 21 policies related to five turnarounds are identified to produce significant improvements in six indicators of human well‐being. By using global and local sensitivity analyses of the E4A model, we suggest that the evolution of the six indicators in the GL scenario can be approximately reached by focusing on just six policies and three turnarounds (namely, the energy, the inequality, and the poverty turnarounds). The evolution of the six indicators can be even improved by investing “reasonably” more on three of these six policies and by keeping unchanged the remaining three. From a methodological point of view, we exploit both global (Sobol) and local sensitivity analyses to identify the policies that most influence the six indicators, and we subsequently execute a scenario analysis of the identified policies to confirm that they can produce a similar (or even a better) evolution of the indicators themselves.
The scale effects of symbiotic relationships under complex driving factors: An empirical study in China
Authors: Chen Hongjia , Zhang Zimeng , Ioppolo Giuseppe , Shi Lei , Wang Zhen , Liu Gang 
Published: November 2024

AbstractSymbiotic relationships between enterprises help mitigate resource and environmental impacts of industrial activities via exchanging waste or by‐products as material inputs among each other. However, the emergence of such symbiotic relationships under complex driving factors across different geographical scales remains hitherto not well understood. Here, we provide an analytic framework including a random forest model and Shannon index, to systematically describe and explain the scale effects of driving factors underlying the symbiotic relationships. Based on a questionnaire survey for 324 enterprises in Chun'an, a typical industrial city in eastern China, we applied this analytical framework. The results show that, first, the quantity of symbiotic relationships exhibits an inversely proportional function across various geographical scales. Second, there exist significant differences in the dominant factors at different scales. Finally, the diversity of importance of factors and the emergence of symbiotic relationships exhibit a consistent trend of fluctuation, providing evidence for the explanatory potential of our proposed analytical framework for the driving mechanisms of emergence. We find that when enterprises are simultaneously affected by multiple driving factors with potent forces (referred to as the diversity of importance), symbiotic behaviors are more likely to occur. Moreover, our results suggest that fostering symbiotic relationships necessitates considering the variations in driving factors across different scales comprehensively and formulating targeted promotional measures tailored to the specific driving factors of different enterprise types. Our proposed framework would help to maximize industrial symbiosis potentials in a specific region.