bluuebunny/crossref_metadata_2025_split huggingface dataset:
Habiter en écovillage, une [éco]utopie du xxie siècle ?
Authors: Amar Sylvia 
Published: November 2024

Nombreuses sont les initiatives qui se mobilisent aujourd’hui pour mieux habiter la Terre. Se positionnant comme des alternatives au monde urbain, les communautés intentionnelles et/ou écovillages font désormais partie des plus dynamiques et plus structurées. Depuis la fin des années 1990, les projets se multiplient à travers le monde, continuant de faire évoluer un mouvement ancien en un réseau international foisonnant et actif sur plusieurs fronts. Face à l’amplification des discours sur les enjeux écologiques, leurs actions concrètes sont particulièrement pertinentes à observer, notamment dans le contexte postérieur à la crise sanitaire mondiale de la Covid-19. Pour présenter la dimension holistique de leur démarche, l’article s’appuie sur les constructions sociospatiales mises en œuvre par quatre écovillages actuellement en activité : La Cité écologique (Canada/États-Unis), Torri Superiore (Italie), Hallingelille (Danemark), le Hameau des Buis (France). Si chacune de ces expériences est unique, toutes se rejoignent en plusieurs points : une volonté d’inscrire leurs choix de vie dans une démarche écologique et éducative connectée à leur territoire d’implantation, un socle de valeurs partagées de par le monde grâce aux outils numériques, un désir d’associer le fondement de leur projet social à la construction d’une architecture à même de l’incarner et d’en soutenir la dimension perfectible. Enfin, parce qu’elle s’inscrit dans une histoire des utopies architecturales qui croise celle des luttes environnementales, leur quête permet de mettre en perspective les enjeux d’éco-habiter contemporains. Vivre, Expérimenter, Construire, sont les axes proposés pour présenter les études de cas citées et mettre en évidence leur capacité à agir sur le réel, même à de très petites échelles.
Les élevages pour questionner la relation à l’animal avec des élèves de maternelle
Authors: Chalmeau Raphaël , Lafitole Monique , Mourgues Sophie , Ramos Béato Maéva , Bergamaschi Gabrielle , Mortelecque Lucile , Sales-Hitier Dorothée 
Published: November 2024

Dès l’école maternelle, les élevages sont recommandés et particulièrement appropriés à la construction d’une démarche d’observation et à une première responsabilisation à l’égard de l’animal. La relation entre humains et non-humains constitue une thématique de recherche renouvelée au regard d’enjeux contemporains liés à la place des humains dans le vivant et à la protection de la biodiversité. Cette question est à l’interface des apprentissages scolaires scientifiques, de la prise en compte de la dimension affective dans ces apprentissages, et de l’acquisition d’une responsabilité vis-à-vis du vivant. Nous présentons les résultats d'une recherche collaborative menée dans quatre classes de maternelle multi-âges sur la construction d'une relation à l'animal. Les données relèvent d’entretiens avec des élèves afin de recueillir leur perception par rapport aux animaux élevés dans la classe (interview ante et post séquence) et d’une discussion autour des soins aux animaux. L'analyse des données permet d’identifier la nature des relations avec les animaux à travers l’implication de dimensions affectives, cognitives et morales dans leur perception de l’animal. Nous discutons de l’intérêt de développer une empathie interspécifique et de sa contribution à la construction d’une posture éthique vis-à-vis des animaux non humains.
La seigneurie ecclésiastique de Saint-Étienne de Troyes
Authors: Lacomme Thomas 
Published: November 2024

La collégiale Saint-Étienne de Troyes, fondée par le pouvoir comtal, responsable d’une partie de la vicomté de Troyes après 1264, eut un rôle dans la « territorialisation » du comté de Champagne, alors même que l’espace qu’elle polarise ne semble pas territorialisé.
Santo veneno: sentidos atribuídos por cuidadores familiares à quimioterapia pediátrica
Authors: Silva-Rodrigues Fernanda Machado , Lucca Milena de , González Mabel Angélica Sánchez , Neris Rhyquelle Rhibna , Araújo Jeferson Santos , André Tatiane Geralda , Nascimento Lucila Castanheira 
Published: November 2024

Objetivo: compreender os sentidos atribuídos por cuidadores familiares de crianças e adolescentes com câncer ao tratamento quimioterápico. Método: estudo qualitativo, com análise secundária suplementar e ampliada de dois estudos desenvolvidos em enfermarias e ambulatório pediátricos, localizados no estado de São Paulo, Brasil. A coleta de dados foi conduzida nos anos de 2017 e 2018, respectivamente. Os dados foram coletados por meio de entrevistas semiestruturadas com 37 cuidadores familiares e analisados conforme análise de conteúdo indutiva. Resultados: a amostra foi composta majoritariamente por mães. A quimioterapia foi percebida como um paradoxo entre o bem e o mal, descrita como um “veneno bom”, que desencadeia uma gama de sentimentos. Os participantes atribuíram a este tratamento os sentidos de um cotidiano repleto de desafios, caracterizados pelas dificuldades em lidar com os efeitos da terapia. Considerações finais: A quimioterapia é percebida pelos cuidadores familiares como um paradoxal "santo veneno", como um tratamento que, apesar de debilitar temporariamente a criança, é essencial para o manejo da doença. Este estudo enriquece o corpo da literatura científica, pois amplia a discussão sobre o tema. Adicionalmente, os resultados obtidos oferecem informações valiosas para os profissionais de saúde e permitem melhor compreensão da perspectiva das famílias durante o complexo processo de quimioterapia pediátrica.
Cotidiano dos profissionais de enfermagem na pandemia de covid-19: invenção da vida e do trabalho
Authors: Santos Luiza Hences dos , Kantorski Luciane Prado , Treichel Carlos Alberto dos Santos , Menezes Etiene Silveira de , Silva Priscilla dos Santos da , Oliveria Michele Mandagará de , Farias Poliana Alves 
Published: November 2024

Objetivo: descrever as táticas e estratégias, durante a pandemia de COVID-19, presentes nas práticas cotidianas dos profissionais de enfermagem e das instituições de saúde. Método: estudo de abordagem qualitativa realizado com 14 profissionais de enfermagem que atuaram no enfrentamento da pandemia de COVID-19. A coleta de dados ocorreu em agosto e setembro de 2021, por meio de entrevistas semiestruturadas, de forma remota. Os dados foram analisados a partir do referencial teórico do estudo do cotidiano norteado pelos conceitos de estratégia e tática de Michel Certeau. Resultados: os profissionais buscaram estratégias da ciência na sua vida privada, como realizar hábitos saudáveis. Estratégias do saber religioso também estiveram presentes. As táticas foram: o cuidado de flores; caminhadas na rua; assistir séries ou filmes. As instituições de saúde utilizaram como estratégia: organização das equipes; trabalho híbrido; oferta de apoio psicológico. No trabalho, as táticas foram o compartilhamento de medos uns com os outros. Considerações Finais: conhecer o cotidiano dos profissionais de enfermagem, nesse momento pandêmico, contribui para compreender o impacto dessa experiência em suas vidas. A construção de saberes a partir das suas práticas cotidianas durante a pandemia de COVID-19 pode ofertar alternativas para enfrentamento dos desafios destes profissionais.
Healthcare professionals’ knowledge and practices in managing ototoxicity in children with cancer
Authors: Ramnarian Kajal , Paken Jessica 
Published: November 2024

Background: Platinum-based chemotherapy poses a risk of ototoxic hearing loss, the effects of which can be devastating in paediatrics with cancer. Childhood hearing loss significantly impacts speech and language acquisition, and educational, psychosocial and emotional development, consequently negatively impacting quality of life. Adequate knowledge and effective management by healthcare professionals in the team managing paediatrics with cancer are, therefore, pivotal to mitigating the severity and impact on quality of life.Objectives: To describe the knowledge and practices of healthcare professionals on the management of ototoxic hearing loss in children receiving platinum-based chemotherapy drugs.Method: Using a descriptive survey design, data were collected from self-administered questionnaires completed by 74 healthcare professionals from two hospitals in KwaZulu-Natal, South Africa.Results: While 45 participants (60.8%) identified ototoxicity as a side effect of platinum-based chemotherapeutic drugs, 43 (58.1%) identified dose, duration and mode of administration as risk factors, and 43 participants (72.9%) did not know the duration of an ototoxicity monitoring programme post-treatment. Fifty participants (68%) accurately identified most of their roles within the ototoxicity monitoring programme. Most participants (n = 73; 99%) did not fully adhere to Health Professions Council of South Africa (HPCSA) ototoxicity monitoring guidelines. However, a positive outcome was that 70 participants (94.6%) acknowledged the importance of the ototoxicity monitoring programme for children receiving platinum-based chemotherapy.Conclusion: The current study demonstrates a clear correlation between healthcare professionals’ practices and their level of knowledge. These findings underscore the importance of improving the knowledge base of healthcare professionals involved in ototoxicity monitoring programme to enhance their practices effectively.Contribution: This study identified areas requiring improvement in managing ototoxicity in this patient group, prompting the inclusion of ototoxicity training. This study supports audiologists in effectively implementing and overseeing ototoxicity monitoring programme.
Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India
Authors: Menon Deepak , Gupta Manisha , Ananthasubramanian Sangeeth Thuppanattumadam , Kulanthaivelu Karthik , Raja Pritam , Ramakrishnan Subasree , Karnam Sangeetha Seshagiri , Saini Jitender , Srijithesh PR , Kulkarni Girish B 
Published: November 2024

Background and Objectives:
Early initiation and maintenance of anticoagulation appears to be the mainstay of treatment of cerebral venous thrombosis (CVT), but the evidence supporting the intensity and duration of anticoagulation is limited.

Methods:
We retrospectively collected data of patients admitted with CVT over a 5-year period, who had a minimum of 6 months of clinical follow-up and three or more prothrombin time international normalized ratio (INR) values spread over 6 months. Data collected included demographic, clinical, and radiologic parameters, anticoagulation status during the follow-up, complications, and clinical status at the last follow-up.

Results:
We identified 204 patients, and the mean age was 34.4 ± 11.1 years. The majority had a provoked etiology (194, 95.1%) for CVT. After initial anticoagulation with unfractionated heparin, all patients transitioned to acenocoumarol or warfarin and this was maintained for a mean duration of 16.02 ± 11.2 months. Time in therapeutic range of INR 2–3 was only 5.1 ± 11.8 percent days and time spent in an INR of 1–1.5 was 68.7 ± 31.8 percent days. The average INR over 6 months was 1.37 ± 0.33. Duration of follow-up was 18.9 ± 13.25 months, and a good outcome was noted in 183 (89.7%) patients. Complications were seen in 29 (14.2%) patients. Multivariate analysis showed only the CVT grading scale score to be an independent predictor of good outcome.

Conclusions:
Maintenance of an intensive level of anticoagulation may not be required in patients with CVT and may be particularly true when a transient and treatable risk factor is the provoking etiology.
Sex-related differences in cognition and its correlation with lipid parameters and sex steroids among community-dwelling older persons in Nigeria
Authors: Mukhtar Isyaku Gwarzo , El-Khashab Mohamed Mabrouk , Salim Muhammad Ali , Ibrahim Salisu Ahmed , Yarube Isyaku Umar 
Published: November 2024

Abstract

Introduction:
Studies on sex-related differences in cognition and its correlation with serum lipids and sex steroids in older persons in sub-Saharan Africa (SSA) are few and inconsistent. Our objectives were to assess: (i) sex-related differences in cognition and (ii) the correlation of cognition with lipid parameters, age, years of formal education, and sex steroids in community-dwelling older persons in Kano state, Nigeria.

Materials and Methods:
About 143 eligible participants were randomly selected. We used the Montreal Cognitive Assessment-Basic (MoCA-B), verbal fluency test, 10-Item Word List Learning Test (10-IWLLT), delayed word list recall, and Stick Design Test (SDT) to assess cognitive function. Serum lipids were determined using chemical colorimetry, whereas sex steroids were determined using competitive enzyme-linked immunosorbent assay kits.

Results:
The results revealed that the participants had a mean age of 66 years. The mean MoCA-B score was 18.84 (males = 20.26, females = 17.73, P = 0.001). Males had better scores in orientation (P = 0.001), abstraction (P = 0.009), naming (P = 0.001), verbal fluency (P = 0.013), delayed word list recall score (P = 0.001), visuo-construction (P = 0.015), and visuo-perception (P = 0.003). Among whole participants, there was a positive correlation between total cholesterol and MoCA-B (r = 0.236, P = 0.005) and between low-density lipoprotein-cholesterol and MoCA-B (r = 0.207, P = 0.013). Serum testosterone had positive correlation with MoCA-B score (r = 0.212, P = 0.001) but negative correlation with delayed word list recall (r = −0.218, P = 0.009), and SDT (r = −0.181, P = 0.031); dihydrotestosterone had positive correlation with MoCA-B score (r = 0.210, P = 0.012) but negative correlation with delayed word list recall (r = −0.243, P = 0.003) and SDT (r = −0.183, P = 0.028). Estradiol had a negative correlation with the 10-IWLLT (r = −0.169, P = 0.044).

Conclusion:
This study concludes that males had better cognition than females. Higher levels of serum lipids and sex steroids are related to better cognition in community-dwelling older persons in Nigeria.
Ectomesenchymal chondromyxoid tumor: A rare case report
Authors: Mondal Anindita , Islam Ayesha Afreen , Basu Keya , Chatterjee Uttara 
Published: November 2024

Abstract
Ectomesenchymal chondromyxoid tumor is a very rare tumor, which mostly occurs in the tongue. Here, we are presenting a case of a 55-year-old man with a swelling in the anterior dorsum of his tongue. The mass was excised and subsequent histopathological examination revealed a subepithelial well-circumscribed mass comprising oval to fusiform tumor cells, arranged in sheets, whorls, and reticular pattern within a prominent chondromyxoid stroma. The tumor cells were positive for glial fibrillary acidic protein, S100, and vimentin, whereas negative for epithelial membrane antigen and p63 on immunohistochemistry. These tumors have to be differentiated from other myxoid lesions, such as oral focal mucinosis, nerve sheath myxoma, soft tissue myxoma, glial choristoma, and ossifying fibromyxoid tumor of soft parts.
A randomized study to compare the efficacy and safety of ketamine, levobupivacaine, and a combination of both as pre-incision surgical site infiltration for providing postoperative analgesia in patients undergoing elective abdominal hysterectomy under general anesthesia
Authors: Yadav Anuj , Mullick Parul , Jain Mansi 
Published: November 2024

Abstract

Objectives:
We aimed to compare the postoperative Visual Analog Scale (VAS) score, requirement of additional analgesia, side-effects, and patient satisfaction among elective hysterectomy patients using ketamine, levobupivacaine, and a combination of both.

Materials and Methods:
A comparative study was conducted on 60 adult females, randomly divided into three groups of Group K: ketamine 1 mg/kg in saline, 20 mL, Group L: levobupivacaine 0.25%, 20 mL, and Group KL: ketamine 1 mg/kg in 0.25% levobupivacaine, 20 mL. The study drug was infiltrated 5 minutes before skin incision. The patient outcomes (hemodynamic parameters, pain, requirement of additional analgesia, and side-effects) were observed during the 24 h after surgery and compared. P < 0.05 was taken for reference in terms of significant results.

Results:
Group KL had the lowest pain VAS score at postoperative 1 h (P = 0.022), 2 h (P = <0.001), and 6 h (P = 0.001). The time of the first dose of pethidine requirement was longer and the cumulative pethidine requirement (24 h) was significantly less in group KL (P < 0.001). Nausea was present in six cases in group K, two cases of Group L, and none from group KL. The patient satisfaction score was significantly greater in group KL (3.30 ± 0.57) as compared to both groups K (1.90 ± 0.44) and L (2.50 ± 0.60), P = 0.0001.

Conclusion:
The combination of ketamine and levobupivacaine is a safe and efficacious alternative as pre-emptive analgesia among patients undergoing abdominal hysterectomies. The combination enhances relief from postoperative pain and provides much better patient satisfaction.
Glycosides of Tripterygium wilfordii Hook. F Inhibits Bone Loss in Rheumatoid Arthritis by Downregulating Interleukin-8/C-X-C Motif Chemokine Receptor 2 Signaling Pathway
Authors: Tian Ya-Ge , Liu Li-Ling , Qi Ming-Zhu , Yang Jing-Hang , Zhu Pan-Pan , Lin Na , Su Xiao-Hui , Kong Xiang-Ying 
Published: November 2024

Objective:
The objective of this study was to investigate the effect of glycosides of Tripterygium wilfordii Hook. F (GTW) on bone erosion in collagen-induced arthritis (CIA) rats and osteoclastogenesis.

Materials and Methods:
The effects of GTW on bone destruction were assessed through hematoxylin and eosin analyses and tartrate-resistant acid phosphatase (TRAP) staining. In vitro, TRAP staining, F-actin, and quantitative polymerase chain reaction assays were used to evaluate the inhibitory effects of GTW on osteoclast differentiation. In addition, Western blot, immunohistochemistry, and immunofluorescence staining techniques were employed to explore the mechanisms of GTW by determining the expression of interleukin-8 (IL-8), C-X-C motif chemokine receptor 2 (CXCR2), nuclear factor of activated T cells 1 (NFATc1), and p65.

Results:
GTW slowed the onset of arthritis and reduced arthritis scores. Our mechanistic studies demonstrated that GTW reduced the number of osteoclasts in rats with CIA and significantly suppressed receptor activator of nuclear factor kappa-B ligand-induced osteoclast differentiation, as evidenced by a decrease in TRAP-positive cells, alterations in F-actin rings, and modulation of osteoclast-specific gene expression. The inhibition of IL-8, CXCR2, NFATc1, and p65 activation by GTW was observed in both CIA rats and osteoclasts. Conversely, the introduction of IL-8 into the osteoclast culture system mitigated the effects of GTW on osteoclast differentiation.

Conclusions:
Our findings suggest that GTW suppressed osteoclastogenesis and bone loss by inhibiting the IL-8/CXCR2 signaling pathway. These results offer valuable insights into the potential therapeutic role of GTW in rheumatoid arthritis and lay the groundwork for future clinical applications.
Compatibility of Kazhdan and Brauer homomorphism
Authors: Dhar Sabyasachi 
Published: November 2024

AbstractLet G be a split connected reductive group defined over
$\mathbb {Z}$
. Let F and
$F'$
be two non-Archimedean m-close local fields, where m is a positive integer. D. Kazhdan gave an isomorphism between the Hecke algebras
$\mathrm {Kaz}_m^F :\mathcal {H}\big (G(F),K_F\big ) \rightarrow \mathcal {H}\big (G(F'),K_{F'}\big )$
, where
$K_F$
and
$K_{F'}$
are the mth usual congruence subgroups of
$G(F)$
and
$G(F')$
, respectively. On the other hand, if
$\sigma $
is an automorphism of G of prime order l, then we have Brauer homomorphism
$\mathrm {Br}:\mathcal {H}(G(F),U(F))\rightarrow \mathcal {H}(G^\sigma (F),U^\sigma (F))$
, where
$U(F)$
and
$U^\sigma (F)$
are compact open subgroups of
$G(F)$
and
$G^\sigma (F),$
respectively. In this article, we study the compatibility between these two maps in the local base change setting. Further, an application of this compatibility is given in the context of linkage – which is the representation theoretic version of Brauer homomorphism.
Some issues of budgetary funding of state servants trainings in the Republic of Armenia
Authors: Gyozalyan Vardush 
Published: November 2024

The article examines and systematically analyzes the system of state financing of trainings of civil servants of the Republic of Armenia, using the methods of economic and statistical analysis. The source for the creation of the analysis database were the State budget indicators of different years, including planned, adjusted and actual data.
Within the framework of the article, there is studied the best international experience of state support for the organization of trainings (on the example of OECD countries) and the possibilities of its localization in RA. There are analized the dynamics and trends of the share of additional education (mainly includes the trainings) in the state budget, problems and gaps in the system of state funding of trainings are revealed according to directions and departments. Based on the analysis, there were made a number of suggestions to improve the system, which will contribute to the qualitative improvement and efficiency of trainings, and the formation of healthy competition among employees. In particular, it is proposed to review the training participation planning system, based on the study of real demand and the implementation of evidence-based policies, which will allow both to save public funds and to organize training according to effective targets.
ԱԴՆԱՆ ՄԵՆԴԵՐԵՍ - ՌԵՋԵՓ ԹԱՅՅԻՓ ԷՐԴՈՂԱՆ․ «ՔԱՂԱՔԱԿԱՆ ՄԱՐՏԻՐՈՍԻ» «ՔԱՂԱՔԱԿԱՆ ԺԱՌԱՆԳԸ»
Authors: Հովհաննիսյան Գոռ 
Published: November 2024

Թուրքիան 2023 թ․ խորհրդարանական և նախագահական ընտրությունների նախընտրական քարոզարշավի շրջան մտավ քաղաքական և սոցիալ-տնտեսական մի շարք խնդիրներով։ Թուրքիայի համար սիմվոլիկ տարեթվի՝ հանրապետության 100-ամյակին համընկնող այս ընտրություններն անցան հասարակության համար քաղաքական ու տնտեսական անկայունության և հետերկրաշարժային ծանր շոկի պայմաններում։ Չնայած այդ հանգամանքին՝ քաղաքական ուժերը վարեցին ակտիվ քարոզարշավ՝ քաղաքական պայքարի բոլոր գրված և չգրված օրենքներով։ Ընտրություններին հատկապես ակտիվ պատրաստվում էր իշխող Արդարություն և զարգացում կուսակցությունը՝ 69-ամյա Ռեջեփ Թայյիփ Էրդողանի գլխավորությամբ, որը, ինչպես որոշ հետազոտողներ նշում էին, պատրաստվում էր իր վերջին և վճռական մարտին։ Քարոզարշավի ժամանակ ավանդական իսլամական պոպուլիզմին և անցյալի փառավորմանը ավելացավ նաև ընդգծված սիմվոլիզմը։ Սակայն այս փուլում անցյալի ոգեկոչումը կենտրոնացած էր ոչ թե ավանդական դարձած օսմանյան նոստալգիայի, այլ ավելի մոտ անցյալի՝ 1950-ականների վրա։ Անցյալի ոգեկոչման հիմնական թիրախը Ժողովրդավարական կուսակցությունն էր, որը եկավ իշխանության 1950 թ․ մայիսի 14-ին՝ վերջ դնելով Մուստաֆա Քեմալ Աթաթյուրքի հիմնադրած Հանրապետական ժողովրդական կուսակցության միանձնյա իշխանությանը։ ԺԿ-ն՝ վարչապետ Ադնան Մենդերեսի ղեկավարությամբ, թուրքական քաղաքական օրակարգ մտցրեց քաղաքական իսլամը, ճանապարհ բացեց իսլամամետ և պահպանողական տարրերի համար, քաղաքական հարթակ տրամադրեց իսլամական զանազան աղանդների և եղբայրությունների ներկայացուցիչներին, սկսեց հարվածել քեմալիզմի 6 սկզբունքներից ամենակարևորներից մեկին՝ աշխարհիկությանը, այնուհետև 1960 թ․ ռազմական հեղաշրջման արդյունքում զրկվեց իշխանությունից։ Հեղաշրջումից հետո դատարանը մահապատժի դատապարտեց արտաքին գործերի նախարար Հասան Փոլաթքանին, ֆինանսների նախարար Ֆաթիհ Ռուշթու Զորլուին և վարչապետ Ադնան Մենդերեսին։ Կարճ ժամանակ անց Ադնան Մենդերեսի մահապատիժը որոշ շրջանակներում հանգեցրեց նրա կերպարի միֆականացման ընդհուպ մինչև սակրալացման՝ որպես «մարտիրոսված» քաղաքական գործիչ։ Այդ շրջանակներից է սերում նաև Էրդողանը, ում՝ որպես քաղաքական գործիչ կայացման մեջ անուղղակի մեծ դեր ունի Ադնան Մենդերեսը։ Հոդվածը նպատակ ունի հետազոտել Ադնան Մենդերեսի քաղաքական ժառանգությունը ստանձնելու և այն «ռեբրեդինգի» ենթարկելու Թուրքիայի ներկայիս ղեկավարի քայլերը և դրա դրսևորումներն ու նպատակները։