bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stimulation-induced side effects after deep brain stimulation – a systematic review
Authors: Zarzycki Marcin Zygmunt , Domitrz Izabela 
Published: August 2019

AbstractObjective:Deep brain stimulation (DBS) was approved by Food and Drug Administration for Parkinson’s disease, essential tremor, primary generalised or segmental dystonia and obsessive-compulsive disorder (OCD) treatment. The exact mechanism of DBS remains unclear which causes side effects. The aim of this review was to assess variables causing stimulation-induced chronic psychiatric/personality-changing side effects.Methods:The analysis of scientific database (PubMed, Cochrane Library, EMBASE) was conducted. The included articles had to be research study or case report and DBS to be conducted in therapeutic purposes. The researches with mental disorders in patients’ medical histories were excluded.Results:Seventeen articles were used in the review. In the group of movement disorders the characteristic of side effects was strongly related to the placement of the electrode implantation. Tiredness/fatigue was correlated with DBS in thalamus. Implantations in subthalamic nucleus were mostly followed by affective side effects such as depression or suicide. The higher voltage of electrode was connected with more severe depression after implantation. The analysis of affective disorder contained only three articles – two about OCD and one about depression. Forgetfulness and word-finding problems as activities connected with cognition may be an inevitable side effect if obsessive thoughts are to be inhibited.Conclusion:DBS of subthalamic nucleus should be seen as the most hazardous place of implantation. As a result there is a strong need of ‘gold standards’ based on the connectivity research and closer cooperation of scientists and clinicians.
Estimating subnational preferences across the European Union
Authors: Lipps Jana , Schraff Dominik 
Published: August 2019

AbstractSubnational analyses of political preferences are substantively relevant and offer advantages for causal inference. Yet, our knowledge on regional political preferences across Europe is limited, not least because there is a lack of adequate data. The rich Eurobarometer (EB) data is a promising source for European-wide regional information. Yet, it is only representative for the national level. This paper compares state-of-the-art methods for estimating regional preferences from nationally representative EB data, validating predictions with regionally representative surveys. Our analysis highlights a number of challenges for estimating regional preferences across Europe, such as data availability, variable selection, and over-fitting. We find that predictions are best using a Bayesian additive regression tree with synthetic post-stratification.
Mediating effect of waist:height ratio on the association between BMI and frailty: the Korean Frailty and Aging Cohort Study
Authors: Kim Minseo , Lee Yunhwan , Kim Eun-Young , Park Yongsoon 
Published: August 2019

AbstractBody weight is a major risk determinant of frailty, but the effect of obesity on frailty is controversial. The present study aimed to confirm the hypothesis that the risk of frailty is positively associated with obesity (BMI ≥ 30 kg/m2), but the association is mediated by the waist:height ratio (WHtR) in older women and men. A total of 2862 community-dwelling older individuals aged 70–84 years were assessed for frailty using the Korean version of Fatigue, Resistance, Ambulation, Illnesses, and Loss of weight index. Obesity (BMI ≥ 30 kg/m2) was associated with a higher risk of frailty compared with BMI 18·5–<23 kg/m2 in all the older individuals (OR 1·88; 95 % CI 1·11, 3·17; P = 0·018) and in older women (OR 1·86; 95 % CI 1·01, 3·42; P = 0·047) before adjusting for WHtR but was not associated with BMI after adjusting for WHtR. Additionally, obesity was not significantly associated with the risk of frailty before and after adjusting for WHtR in older men. Mediation analysis revealed that the association between BMI and frailty score was mediated by WHtR. Moreover, the mediating effect of WHtR on frailty score was positive in both women and men, but the frailty score was associated with BMI positively in women and negatively in men. The present study suggests that the risk of frailty is higher in obese women, which is mediated by WHtR, but not in obese men.
Maternal dietary selenium intake is associated with increased gestational length and decreased risk of preterm delivery
Authors: Barman Malin , Brantsæter Anne Lise , Nilsson Staffan , Haugen Margaretha , Lundh Thomas , Combs Gerald F. , Zhang Ge , Muglia Louis J. , Meltzer Helle Margrete , Jacobsson Bo , Sengpiel Verena 
Published: August 2019

AbstractThe first positive genome-wide association study on gestational length and preterm delivery showed the involvement of an Se metabolism gene. In the present study, we examine the association between maternal intake of Se and Se status with gestational length and preterm delivery in 72 025 women with singleton live births from the population-based, prospective Norwegian Mother, Father and Child Cohort Study (MoBa). A self-reported, semi-quantitative FFQ answered in pregnancy week 22 was used to estimate Se intake during the first half of pregnancy. Associations were analysed with adjusted linear and Cox regressions. Se status was assessed in whole blood collected in gestational week 17 (n 2637). Median dietary Se intake was 53 (interquartile range (IQR) 44–62) µg/d, supplements provided additionally 50 (IQR 30–75) µg/d for supplement users (n 23 409). Maternal dietary Se intake was significantly associated with prolonged gestational length (β per sd = 0·25, 95 % CI, 0·07, 0·43) and decreased risk of preterm delivery (n 3618, hazard ratio per sd = 0·92, 95 % CI, 0·87, 0·98). Neither Se intake from supplements nor maternal blood Se status was associated with gestational length or preterm delivery. Hence, the present study showed that maternal dietary Se intake but not intake of Se-containing supplements, during the first half of pregnancy was significantly associated with decreased risk of preterm delivery. Further investigations, preferably in the form of a large randomised controlled trial, are needed to elucidate the impact of Se on pregnancy duration.
Don't Call It a Comeback: Autocratic Ruling Parties After Democratization
Authors: Miller Michael K. 
Published: August 2019

AbstractWhen autocratic ruling parties accede to democratization, they do not always fade away into history. Following forty-one transitions since 1940, including those in Mexico, Taiwan, Bulgaria and Ghana, the ruling party survived and won power after democratization. Why do some former autocratic parties prosper under democracy while others quickly dissolve? What effect does this have on democratic survival? This article uses original data to predict the post-transition fates of eighty-four autocratic ruling parties through 2015. Whereas extant theories emphasize radical reinvention and outsider struggle, the author argues that success is instead about maintaining ruling-party advantages into the democratic period. Parties succeed when they have authoritarian legacies that easily translate to democratic competition, such as broad programmatic experience, strong organization and policy success. In addition, democratic institutions that disadvantage new parties and actors benefit autocratic parties. Lastly, an instrumental variables design shows that autocratic party success negatively impacts democratic survival and quality.
Media's Influence on LGBTQ Support Across Africa
Authors: Winkler Stephen 
Published: August 2019

AbstractPolitical leaders across Africa frequently accuse the media of promoting homosexuality, while activists often use the media to promote pro-LGBTQ (lesbian, gay, bisexual, transgender and queer) narratives. Despite extensive research on how the media affects public opinion, including studies that show how exposure to certain information can increase support of LGBTQs, there is virtually no research on how the media influences attitudes towards LGBTQs across Africa. This study develops a theory that accounts for actors' mixed approach to the media and shows how different types of media create distinct effects on public opinion of LGBTQs. Specifically, the study finds that radio and television have no, or a negative, significant effect on pro-gay attitudes, whereas individuals who consume more newspapers, internet or social media are significantly more likely to support LGBTQs (by approximately 2 to 4 per cent). The author argues that these differential effects are conditional on censorship of queer representation from certain mediums. The analysis confirms that the results are not driven by selection effects, and that the relationship is unique to LGBTQ support but not other social attitudes. The results have important implications, especially given the growing politicization of same-sex relations and changing media consumption habits across Africa.
Why Do They Run? The Psychological Underpinnings of Political Ambition
Authors: Blais Julie , Pruysers Scott , Chen Philip G. 
Published: August 2019

AbstractWhat drives individuals toward a career in politics? Prior research on political ambition has often focused on socio-demographic variables while generally ignoring the importance of individual personality differences. Yet personality consistently predicts political knowledge, interest and participation, suggesting that individual differences may matter in addition to resources and the social environment. To this end, we assess the impact of both the HEXACO and Dark Triad models of personality in predicting nascent political ambition (that is, the initial desire to run for elected office) while controlling for well-established socio-demographic variables (for example, gender, income). Overall, we find considerable support for the predictive power of personality, especially the traits of honesty-humility, extraversion and narcissism. These results have important implications for understanding the kinds of people who are interested in a political career.
Is Indigeneity like Ethnicity? Theorizing and Assessing Models of Indigenous Political Representation
Authors: Williams Meaghan , Schertzer Robert 
Published: August 2019

AbstractWithin the broader literature on political representation, studies exploring Indigenous forms of representation are rather limited. Where they exist, they tend to explore how Western models of political representation include Indigenous peoples, conflating Indigenous groups with ethnic minorities. This article asks whether and how Indigenous political representation might be distinguished from the representation of ethnic minorities. Our argument is that Indigenous groups’ identities tend to be based on different claims and relationships to the state than ethnic groups, which leads to political mobilization seeking a means to respond to the colonial nation-state project. We develop a theoretical framework that identifies three principles that ought to inform an effective and legitimate model of Indigenous political representation: recognition, protection and decolonization. We then apply this theoretical framework to assess the extent to which existing models of Indigenous representation in Bolivia, Canada, New Zealand and Norway correspond with these three principles.
Inter-relationships among psychopathology, premorbid adjustment, cognition and psychosocial functioning in first-episode psychosis: a network analysis approach
Authors: Chang W. C. , Wong C. S. M. , Or P. C. F. , Chu A. O. K. , Hui C. L. M. , Chan S. K. W. , Lee E. M. H. , Suen Y. N. , Chen E. Y. H. 
Published: August 2019

AbstractBackgroundBetter understanding of interplay among symptoms, cognition and functioning in first-episode psychosis (FEP) is crucial to promoting functional recovery. Network analysis is a promising data-driven approach to elucidating complex interactions among psychopathological variables in psychosis, but has not been applied in FEP.MethodThis study employed network analysis to examine inter-relationships among a wide array of variables encompassing psychopathology, premorbid and onset characteristics, cognition, subjective quality-of-life and psychosocial functioning in 323 adult FEP patients in Hong Kong. Graphical Least Absolute Shrinkage and Selection Operator (LASSO) combined with extended Bayesian information criterion (BIC) model selection was used for network construction. Importance of individual nodes in a generated network was quantified by centrality analyses.ResultsOur results showed that amotivation played the most central role and had the strongest associations with other variables in the network, as indexed by node strength. Amotivation and diminished expression displayed differential relationships with other nodes, supporting the validity of two-factor negative symptom structure. Psychosocial functioning was most strongly connected with amotivation and was weakly linked to several other variables. Within cognitive domain, digit span demonstrated the highest centrality and was connected with most of the other cognitive variables. Exploratory analysis revealed no significant gender differences in network structure and global strength.ConclusionOur results suggest the pivotal role of amotivation in psychopathology network of FEP and indicate its critical association with psychosocial functioning. Further research is required to verify the clinical significance of diminished motivation on functional outcome in the early course of psychotic illness.
Cost-analysis of virtual reality training based on the Virtual Reality for Upper Extremity in Subacute stroke (VIRTUES) trial
Authors: Islam M. Kamrul , Brunner Iris 
Published: August 2019

AbstractObjectivesStroke is a major cause of lasting disability worldwide. Virtual reality (VR) training has been introduced as a means of increasing the effectiveness of rehabilitation by providing large doses of task-related training with many repetitions and different modes of feedback. As VR is increasingly used in neurorehabilitation, cost considerations are important.MethodsA cost-analysis was conducted based on the Virtual Reality for Upper Extremity in Subacute stroke (VIRTUES) trial, a recent international randomized controlled observer-blind multicenter trial. Average therapist time required per therapy session may differ between VR and conventional training (CT), leading to potential cost savings due to a therapist being able to supervise more than one patient at a time. Exploratory cost analyses are presented to explore such assumptions.ResultsBased on our calculations, VR incurs extra costs as compared with CT when the same amount of therapist contact is provided, as was the case in VIRTUES. However, the exploratory analyses demonstrated that these costs may be rapidly counterbalanced when time for therapist supervision can be reduced.ConclusionsExtra costs for VR can be outweighed by reduced therapist time and decreasing VR system costs in the nearer future, and not least by increased patient motivation.
Public support for protected areas in new forest frontiers in the Brazilian Amazon
Authors: Cunha Helenilza Ferreira Albuquerque , Souza Adriano Ferreira de , Cardoso da Silva José Maria 
Published: August 2019

SummaryGazetting and maintaining protected areas (PAs) are political processes and, as such, depend on wider society’s support in order to achieve their aims. In this paper, we evaluated the influence of gender, education, age, income, place of origin and place of residence on public support for PAs in the Brazilian state of Amapá, a new tropical forest frontier. We gathered 615 complete interviews with adults living in both rural and urban settings. We found that most (90.5%) of the participants support PAs and that this attitude is more likely to exist among urban than rural participants. We found that gender, education, age, income and place of origin did not influence support for PAs. Biodiversity conservation is the most common reason why PAs receive public support. In contrast, participants who do not favour PAs see them as providing no benefit to people. We suggest that support by local political leaders from dominant and rival political parties for conservation helps to promote acceptance of PAs by stakeholders. However, relatively low support for PAs among rural participants could indicate that the expectations of these populations regarding the social benefits associated with this conservation policy have yet to be fulfilled.
Malnutrition and related risk factors in older adults from different health-care settings: an enable study
Authors: Kiesswetter Eva , Colombo Miriam G , Meisinger Christa , Peters Annette , Thorand Barbara , Holle Rolf , Ladwig Karl-Heinz , Schulz Holger , Grill Eva , Diekmann Rebecca , Schrader Eva , Stehle Peter , Sieber Cornel C , Volkert Dorothee 
Published: August 2019

AbstractObjective:The origin of malnutrition in older age is multifactorial and risk factors may vary according to health and living situation. The present study aimed to identify setting-specific risk profiles of malnutrition in older adults and to investigate the association of the number of individual risk factors with malnutrition.Design:Data of four cross-sectional studies were harmonized and uniformly analysed. Malnutrition was defined as BMI < 20 kg/m2 and/or weight loss of >3 kg in the previous 3–6 months. Associations between factors of six domains (demographics, health, mental function, physical function, dietary intake-related problems, dietary behaviour), the number of individual risk factors and malnutrition were analysed using logistic regression.Setting:Community (CD), geriatric day hospital (GDH), home care (HC), nursing home (NH).Participants:CD older adults (n 1073), GDH patients (n 180), HC receivers (n 335) and NH residents (n 197), all ≥65 years.Results:Malnutrition prevalence was lower in CD (11 %) than in the other settings (16–19 %). In the CD sample, poor appetite, difficulties with eating, respiratory and gastrointestinal diseases were associated with malnutrition; in GDH patients, poor appetite and respiratory diseases; in HC receivers, younger age, poor appetite and nausea; and in NH residents, older age and mobility limitations. In all settings the likelihood of malnutrition increased with the number of potential individual risk factors.Conclusions:The study indicates a varying relevance of certain risk factors of malnutrition in different settings. However, the relationship of the number of individual risk factors with malnutrition in all settings implies comprehensive approaches to identify persons at risk of malnutrition early.
Prevalence of overweight and obesity in Mozambique in 2005 and 2015
Authors: Fontes Filipa , Damasceno Albertino , Jessen Neusa , Prista António , Silva-Matos Carla , Padrão Patrícia , Lunet Nuno 
Published: August 2019

AbstractObjective:The ongoing demographic, nutritional and epidemiological transitions in sub-Saharan Africa highlight the importance of monitoring overweight and obesity. We aimed to assess the prevalence of overweight and obesity in Mozambique in 2014/2015 and compare the estimates with those obtained in 2005.Design:Cross-sectional study conducted in 2014/2015, following the WHO Stepwise Approach to Chronic Disease Risk Factor Surveillance (STEPS). Prevalence estimates with 95 % CI were computed for different categories of BMI and abdominal obesity, along with age-, education- and income-adjusted OR. The age-standardized prevalence in the age group 25–64 years was compared with results from a STEPS survey conducted in 2005.Setting:Mozambique.Participants:Representative sample of the population aged 18–64 years (n 2595).Results:Between 2005 and 2014/2015, the prevalence of overweight and obesity increased from 18·3 to 30·5 % (P < 0·001) in women and from 11·7 to 18·2 % (P < 0·001) in men. Abdominal obesity increased among women (from 9·4 to 20·4 %, P < 0·001), but there was no significant difference among men (1·5 v. 2·1 %, P = 0·395). In 2014/2015, the prevalence of overweight and obesity was more than twofold higher in urban areas and in women; in the age group 18–24 years, it was highest in urban women and lowest in rural men.Conclusions:In Mozambique, there was a steep increase in the prevalence of overweight and obesity among adults between 2005 and 2014/2015. Overweight and obesity are more prevalent in urban areas and among women, already affecting one in five urban women aged 18–24 years.
Flower-Like MoS2 for Next-Generation High-Performance Energy Storage Device Applications
Authors: Majumder Sumit , Banerjee Sangam 
Published: August 2019

AbstractHere, a well crystalline 3D flower-like structured MoS2 (~420 nm) has been successfully synthesized on a large scale by a simple hydrothermal technique. The evolution of morphology in the formation process has also been investigated. The crystallinity, purity, and morphology of the sample are characterized by powder X-ray diffraction, Fourier-transform infrared spectroscopy, fieldemission scanning electron microscopy (FESEM), and transmission electron microscopy (TEM) techniques. The FESEM and TEM images reveal that the sample exhibits a uniform 3D flower-like microsphere shape with folded nanosheets, which are stretched out along the edge of the microsphere. The electrochemical performance of the sample has been investigated by cyclic voltammogram, galvanostatic charge–discharge, and electrochemical impedance spectroscopy studies. The results of the electrochemical analysis suggest that the material delivers a maximum specific capacitance (Csp) of 350 F/g at a discharge current density of 0.25 A/g with energy density 17.5 Wh/kg. It also exhibits good capability and excellent cyclic stability (94% capacity retention after 1,000 cycles in 1 A/g) owing to the coupling effect of electrical conductivity with the interesting morphology and larger active surface area. Hence, the sample may be used as a promising electrode material for high-performance energy storage devices.