bluuebunny/crossref_metadata_2025_split huggingface dataset:
Levetiracetam in der Behandlung des Status epilepticus – ein update
Authors: Rösche Johannes , Dudek Maria , Teleki Anna , Godau Jana , Bösel Julian 
Published: July 2019

ZusammenfassungSeit 2004 liegen Publikationen zum Einsatz von Levetiracetam beim Status epilepticus vor. In der vorliegenden Arbeit werden basierend auf einer PubMed-Literatur-Recherche vom 06.07.2018 die nach dem 12.12.2011 erschienenen Arbeiten zusammenfassend dargestellt und in der Diskussion mit den älteren Arbeiten verglichen. Es wurden 28 Behandlungsepisoden in Berichten über 1-2 Fälle und 412 Behandlungsepisoden in Fallserien und prospektiven Studien beschrieben. Dabei ließ sich aus den Fallserien und Studien ein hochwahrscheinlicher Mittelwert der Erfolgsrate für die Status-Durchbrechung von 55,0 %-59,4 % ableiten. Auf-grund des zu vermutenden verzögerten Wirkungseitritts des Levetiracetams ist sein Einsatz beim Status generalisierter tonisch-klonischer Anfälle dennoch zu hinterfragen. Als Loading-Dosis erscheinen 30 mg / kg KG angemessen
An Ultrasound Scoring Model for the Prediction of Intrapartum Morbidly Adherent Placenta and Maternal Morbidity: A Cross-Sectional Study
Authors: El-Haieg Dahlia O. , Madkour Nadia M. , Basha Mohammad Abd Alkhalik , Ahmad Reda A. , Sadek Somayya M. , Ibrahim Safaa A. , Sibai Hoda , Mahdy Entesar R. , Abd Elhady Rasha R. , Mohamed Elshaimaa Mohamed , Khamis Mai E. M. , Azmy Taghreed M. 
Published: July 2019

Abstract
Objective To design an ultrasound scoring model for the prediction of the intrapartum morbidly adherent placenta (MAP) and maternal morbidity.
Patients and Methods 114 females with singleton pregnancies ≥ 28 weeks of gestation referred for suspicion of MAP were included. All patients underwent examination by two-dimensional ultrasound with the color Doppler setting. Five signs were evaluated: the retroplacental echolucent space, placental lacunae, the hyperechoic uterine-bladder interface, retroplacental myometrium thickness, and subplacental, uterine serosa-bladder wall, intraplacental and bladder wall vascularity. We designed a score ranging from 0–8.5 points, including the five signs according to their odds ratios and evaluated its prediction for MAP and maternal morbidity.
Results Using multivariate logistic regression, all ultrasound signs were significant dependent predictors for both MAP and maternal morbidity (myometrium thickness < 1 mm followed by lacunae ≥ 4 and lost retroplacental echolucent space). The only independent predictors for MAP were myometrium thickness < 1 mm and lacunae ≥ 4, while myometrium thickness < 1 mm and lost retroplacental echolucent space were predictive for maternal morbidity. The score showed a perfect agreement with MAP and a good one for maternal morbidity.
Conclusion Application of the score we designed can improve the ultrasound diagnosis of MAP and the maternal outcome.
Association Between Glycaemic Control and the Intake of Thiazide Diuretics, Beta Blockers and Levothyroxine in People Without Diabetes
Authors: Roth Johannes , Müller Nicole , Kuniss Nadine , Wolf Gunter , Müller Ulrich Alfons 
Published: July 2019

Abstract
Objective The pharmacological additional information for many medications includes warnings stating that the blood sugar control may be worsened by the intake of certain drugs. However a quantification of the effects is missing. This may result in confusion for patients as well as for their physicians. The aim of this study was to assess a potential association between medication (beta blockers, thiazides, levothyroxine) and HbA1c in people without diabetes.
Methods In this cross-sectional study we analysed data from 2 921 people (7 699 visits) without diabetes (age 46.6 y; 69.1% women; BMI 27.6±6.4 kg/m²; HbA1c 5.2%) who had at least one HbA1c determination and a complete documentation of their drug intake. An oral glucose tolerance test was not performed. The participants were divided in 8 groups (no regular drug intake, levothyroxine alone, beta blockers alone, thiazides alone, combination 2 of 3, combination of all 3). Patients with known distorting influences of the HbA1c were excluded.
Results People with no regular drug intake had an HbA1c of 5.4% [35.8 mmol/mol]. The HbA1c of the group that took all 3 drugs in combination was 5.6% [38.2 mmol/mol]. A multiple linear mixed model showed an increase in HbA1c for thiazides (β=0.0558, p=0.025) and a decrease for combination of levothyroxine and thiazide (β=−0.0765, p=0.010).
Conclusion Thiazides and the combination of levothyroxine and thiazides were associated with slight changes in HbA1c. In this study there was no association between the intake of beta blockers and HbA1c. At least for people without diabetes these effects seem to be of minor importance.
An Infant with Apert Syndrome and Tetralogy of Fallot for Craniosynostosis Correction: Anesthetic Challenges
Authors: Lionel Karen R. , Sundararajan Satish K. , Moorthy Ranjith K. , Mariappan Ramamani 
Published: July 2019

AbstractApert syndrome (AS) is an autosomal dominant disorder characterized by craniosynostosis, craniofacial anomalies, and symmetrical syndactyly of hands and feet. Ten percent children with AS can have associated congenital cardiac anomalies. Association of complex cyanotic heart disease with craniosynostosis is very rare. So far, only one case has been reported in the literature. The craniosynostosis corrective surgery is associated with the risk of massive bleeding or venous air embolism, which can cause paradoxical air embolism and precipitate cyanotic spell, which makes the anesthesia more challenging. In this report, we present the anesthetic challenges of an 8-month-old infant with AS and tetralogy of Fallot for craniosynostosis correction.
FGFR1 Mosaic Pathogenic Variant in Encephalocraniocutaneous Lipomatosis with Leptomeningeal Angiomatosis
Authors: Gómez-García de la Banda Marta , Fernández-Álvarez Paula , Sánchez-Montañez García-Carpintero Ángel , García-Patos Vicenç , Tizzano Eduardo F. , Boronat Susana 
Published: July 2019

AbstractEncephalocraniocutaneous lipomatosis (ECCL) is a congenital neurocutaneous disorder. It is characterized by ocular anomalies (epibulbar choristomas), skin lesions (as nevus psiloliparus and subcutaneous lipomas), and central nervous system abnormalities (mostly arachnoid cysts, brain anomalies, vascular defects, and intracranial and spinal lipomas). Mutations in KRAS and fibroblast growth factor receptor gene-1 (FGFR1) are related to ECCL, explaining additional manifestations such as jaw tumors or gliomas. We report a pediatric patient with clinical, radiological, and histological findings consistent with ECCL and a mosaic pathogenic variant in FGFR1 found in the DNA from a non-cultured biopsy of the nevus psiloliparus and absent in blood and DNA from buccal mucosa.
Stylistic humor across modalities
Authors: Piata Anna 
Published: July 2019

AbstractThis paper is concerned with ‘Classical Art Memes’, a category of internet memes that distinctively derives its visual input from classical and medieval art. I specifically show that humor in Classical Art Memes arises from incongruity among different stylistic varieties, namely a colloquial linguistic expression in the text and a classical-style artwork in the image. Given that stylistic incongruity cross-cuts modalities, I further argue that Classical Art Memes make a case for what I call ‘multimodal stylistic humor’. The analysis is based on a small corpus ofwhen-memes, whereby the image complements awhen-clause. The findings of the study suggest that humor in Classical Art Memes serves to convey affective meanings that emerge from the embodied affect in the image that is textually recontextualized in contemporary terms. Such meanings ultimately convey a critical commentary on knowable features of modern life.
Understanding Turkish Rhetoric in the Intertextuality of Two Seminal Texts: The Orkhon Inscriptions and Atatürk’s Nutuk
Authors: Guler Elif , Goksel Iklim 
Published: July 2019

ABSTRACT
This study contributes to the conversations on a more globalized and inclusive rhetorical praxis by focusing on how rhetoric was produced and understood by Turks – a group whose history spans centuries since their ancient origins in central Asia. We examine the ways in which Turkic/Turkish rhetoric was practiced and conceptualized in two seminal texts from the pre-Islamic and republican periods of the Turkish rhetorical tradition: the Orkhon inscriptions (8th century) and Atatürk’s Nutuk (1927). The intertextuality of these texts allows us to explore their relationships across time and space as well as mediate rhetorical styles and performances in their discourse.
Transnational land acquisitions beyond the food and financial crises
Authors: Mechiche-Alami Altaaf , Piccardi Carlo , Nicholas Kimberly A , Seaquist Jonathan W 
Published: July 2019

Abstract
Large-scale land acquisitions (LSLA) in resource-rich countries came to global attention after the food and financial crises of 2008. Previous research has assessed the magnitude of these land investments in terms of land areas acquired. In this study, we analyze the trends in the evolution of LSLA by framing the latter as virtual land trade network with land transactions occurring between 2000 and 2015, in order to shed light on the development and evolution of this system. Based on an index we introduce to represent both the number of countries and size of deals, we discover three main phases of trade activity: a steady increase from 2000 until 2007 (Phase 1) followed by a peak coinciding with the food and financial crises between 2008 and 2010 (Phase 2) and concluded by a decline from 2011 to 2015 (Phase 3). We identify 73 countries that remained active in land trading during all three phases and form a core of land traders much larger than previously thought. Using network analysis methods, we group countries with similar trade patterns into categories of competitive, preferential, diversified, and occasional importers or exporters. Finally, in exploring the changes in investors and their interests in land throughout the phases, we attribute the evolution of LSLA to the different stages in the globalization and financialization of different industries. By showing that land investments seem fully integrated as investment strategies across industries we argue for the urgency of better regulation of LSLA so that they also benefit local populations without damaging the environment regardless of their primary purpose.
Selection for drought-resistant rice (Oryza sativa L.) using polyethylene glycol
Authors: Purbajanti E D , Kusmiyati F , Fuskhah E , Rosyida R , Adinurani P G , Vincēviča-Gaile Z 
Published: July 2019

Abstract
The study was expected to provide information poly ethylene glycol (PEG) concentration that can be used for plant breeding base rice (Oryza sativa L.) plant. The research was conducted covering two experimentals stage, were (i). Tests of dry stress resistance of six cultivars of rice using PEG 6000, and (ii). Emerged test seeds of six rice cultivars that have been subjected to dry stress with PEG 6000. The treatments were designed based on a complete randomized design of two factors. The first factor used six cultivars of rice were cv.Mekongga, cv. Way Apo Buru, cv. Sidenuk, cv. Pepe, cv. Ciherang and cv. IR64. and the second factor was dry stress [(0, 5, 10 and 15) % of PEG] with replicates three times. The higher concentration of PEG lowered growth rate (GR), emergence rate (ER), germination energy (GE) and the relative germination rate on all cultivars of rice. Germinate the longer time, appropriate concentrations of PEG. Test of pre-emergence on soil giving the mixed response on all cultivars of rice and PEG level. Cv. Mekongga, cv. Sidenuk, cv. Pepe and cv. Ciherang have the ability to grow on soil test. Canopy and root length highest on cv. IR64. Cv. Sidenuk popularity score can be classified moderate tolerance, while cv. Pepe that was sensitive to drought stress.
The performance of three local rice (Oryza sativa L.) cultivar from East Kalimantan - Indonesia under drought stress at early seedling stage
Authors: Artadana I B M , Dewi I T , Sukweenadhi J 
Published: July 2019

Abstract
Climate change made rain fall unpredictable leading to sudden drought stress during crop cultivation period. Drought stress affects the crop growth and development, especially during the seedling period. This research aims to evaluate the performance of three local rice seedling under drought stress induced by PEG 6000. Three local rice cultivars were germinated and then divided into five groups. In the 3 d after germination, each group were treated in vitro with either 0 %, 10 %, 15 %, 20 % or 25 % PEG 6000 solution for 10 d in vitro. Drought stress was continued for 14 d ex vitro in rice treated with 0 % and 25 % PEG. Osmotic stress induced by PEG significantly reduced plant growth and total chlorophyll content in the leaf. In vitro study showed rice seedling growth reduction was increased when the PEG 6000 increased. Ex vitro study with application of 25 % PEG showed cv. Telaseh more tolerant to drough stress at the seedling stage compare to cv.. Mayas Kuning and cv. Mayas Putih. Additionally, drought stress induced increasing of soluble sugar in the leaf of all rice cultivars. This might indicate that soluble sugar plays a role as osmoprotectant under drought stress in those three cultivars.
The potential of extract of Zingiber zerumbet (L.) Smith as a feed additive to improve the production performances and meat nutritional composition of broiler chickens
Authors: Rahayu I D , Widodo W , Prihartini I , Winaya A , Zalizar L , Untari T , Mel M 
Published: July 2019

Abstract
This study aimed at replacing the use of antibiotic growth promoters (AGP) as the feed additive with the Zingiber zerumbet (L.) Smith extract (ZZE) to control Salmonellosis in broiler chickens. This study employed the completely randomized design (CRD), five treatments, namely: T0 (basal diet), T1 (basal diet + S. enteridis infection), T2 (basal diet + S. enteridis infection + 0.33 % ZZE), T3 (basal diet + S. enteridis infection + 0.67 % ZZE), and T4 (basal diet + S. enteridis infection + 1 % ZZE). The addition of the Z. zerumbet extract did not seem to affect the production performances, in which the average feed consumption was 69.38 g ± 4.43 g to 72.71 g ± 4.92 g, body weight gain was 35.67 g ± 1.40 g to 38.30 g ± 3.85 g, feed conversion was 1.89 ± 0.11 to 2.04 ± 0.11, final weight was 1 287.80 g ± 49.97 g up to 1 380.50 g ± 134.90 g, and percentage of carcass was 60.90 % to 68.48 %. However, the use of Z. zerumbet extract with the highest concentration at 1 % decreased the crude fat of meat.
Comparison of energy production, net energy balance, net energy ratio, and renewable index for biodiesel production from oil palm (Elaeis guineensis Jacq.) and jatropha (Jatropha curcas L.) based on life cycle assessment
Authors: Siregar K , Tambunan A H , Sholihati  , Wirawan S S , Araki T 
Published: July 2019

Abstract
Biodiesel is produced mostly from oil palm (Elaeis guineensis Jacq.) and jatropha (Jatropha curcas L.) and used intensively in Indonesia. This happened because since 2007 Indonesia has become the main palm oil producer in the world. On the other hand, jatropha is a non-edible and easy to grow industrial plant in various regions in Indonesia, which makes it a good alternative for the production of biodiesel fuel. The objective of this research is to calculate and analyze the consumption of energy production, renewable energy, non-renewable energy, fossil energy and see the relationship of net energy balance (NEB), net energy ratio (NER), and renewable index (RI) for biodiesel production from E. guineensis and J. curcas based on life cycle assessment (LCA) which reflects the condition of Indonesia. The result showed that the energy input in oil palm is higher than J. curcas which reflected by higher NEB and lower RI value. The NEB value of E. guineensis and J. curcas is 146 948.08 and 39 334.79, repectively. The RI value of E. guineensis and J. curcas is 0.162 and 0.270, respectively. NER value of BDF-CPO (biodiesel fuel-crude E. guineensis) and BDF-CJCO (biodiesel fuel-crude J. curcas oil) is higher than 1.
The drought stress tolerance of physic nut (Jatropha curcas Linn.) genotypes
Authors: Maftuchah  , Fahmi I Z , Zainudin A , Ikhwan A , Djumali  , Kuan L K 
Published: July 2019

Abstract
Physic nut (Jatropha curcas Linn.) is one of tropical plant that has a potential as an alternative energy source. This study aimed at finding out the drought tolerance level of six genotypes of J.curcas based on the morphology and production of the first harvest time. The plant was treated under a condition of 100 %, 70 % and 40 % field capacity. The tested genotypes were 5-1-14 (SP8 × SP16), 6-2-10 (SP8 × SP38), 7-2-8 (SP33 × HS49), 18-1-14 (SM35 × SP38), IP3A and IP3P. The drought stress of 40 % ground water inhibited the plant vegetative and generative growth (the amount of leaves, male flower, carpel, hermaphrodite flower and the percentage of formed fruit) while at the same time it tended to reduce the amount of fruit and the seeds’ dry weight. The level of drought that reached 70 % resulted in the reduce of seeds’ dry weigh up to 87.76 % and upon 40 % of drought level, the seeds’ dry level was reduced nearly to 97.92 %. At 40 % moisture content, the highest percentage of fruit formation is achieved by genotypes 5-1-14 and 6-2-10.
Genome-wide SNP-discovery and analysis of genetic diversity in oil palm using double digest restriction site associated DNA sequencing
Authors: Nugroho Y A , Tanjung Z A , Yono D , Mulyana A S , Simbolon H M , Ardi A S , Yong Y Y , Utomo C , Liwang T 
Published: July 2019

Abstract
The oil palm conventional breeding is faced with many challenges, including the long breeding cycle and limited genetic variations available from the existing breeding populations. Recent genomic research revealed the genetic properties of various oil palm populations and could be exploited by recombining favorable alleles through molecular breeding and selection. In aimed to discover high quality single nucleotide polymorphisms (SNPs) sampled from 236 diverse genetic backgrounds palms, a paired-end ddRAD-sequencing was employed to discover allelic variations. Whole 195.62 Gb clean data were generated using ddRAD-seq. After stringent filtering, 8 189 SNPs in the annotated genes were discovered based on the oil palm EG05 reference genome. The high polymorphism rate was observed across the assayed populations, whereby 29 % of loci showed moderate to high putative impact on amino acid changes in silico as predicted by SnpEff software. The Angola and Deli origins seemed to have undergone inbreeding as reflected by the fixation index and the lower observed heterozygosity compared to expected heterozygosity. Assessment of genetic stratification and structure was not strong enough to differentiate the core breeding materials according to their prior genetic backgrounds. The results demonstrated the robustness and high-throuputness of ddRAD sequencing method for SNP discovery.
Measurement-device-independent quantum key distribution coexisting with classical communication
Authors: Valivarthi R , Umesh P , John C , Owen K A , Verma V B , Nam S W , Oblak D , Zhou Q , Tittel W 
Published: July 2019

Abstract
The possibility for quantum and classical communication to coexist on the same fiber is important for deployment and widespread adoption of quantum key distribution (QKD) and, more generally, a future quantum internet. While coexistence has been demonstrated for different QKD implementations, a comprehensive investigation for measurement-device independent (MDI) QKD—a recently proposed QKD protocol that cannot be broken by quantum hacking that targets vulnerabilities of single-photon detectors—is still missing. Here we experimentally demonstrate that MDI-QKD can operate simultaneously with at least five 10 Gbps bidirectional classical communication channels operating at around 1550 nm wavelength and over 40 km of spooled fiber, and we project communication rates in excess of 10 THz when moving the quantum channel from the third to the second telecommunication window. The similarity of MDI-QKD with quantum repeaters suggests that classical and generalized quantum networks can co-exist on the same fiber infrastructure.
Frequency of a state of cloud systems over tropical warm ocean
Authors: Kumar Shailendra , Bhat G S 
Published: July 2019

Abstract
The knowledge of how long a mesoscale convective system stays in a given stage of life cycle is an important information for many practical applications. A unique approach has been adopted here to find the stage of development of convective cloud systems (CCSs) over tropical oceanic areas. We use the Tropical Rainfall Measuring Mission (TRMM) data products, and define a cloud system (CS) based on criteria that depend on TRMM precipitation radar equivalent radar reflectivity factor (Z
e) and TRMM Microwave Imager polarization corrected temperature data. Average vertical profile of Z
e and convective area fraction (CAF) of a CS are used to identify its state which is a proxy for life stage. We use two parameters, namely reflectivity differences (RD) and convective area fraction (CAF) and defined 5 states of CS life cycle. Our results show that majority of CSs are found in mature stage and formative and dissipation stages are relatively short over the twelve warm tropical oceanic areas selected for analysis. Each ocean has a distinct signature in the RD-CAF phase space, and, there are regional/seasonal differences within an ocean basin. Bay of Bengal has less CAF compared to the equatorial Indian ocean. In the tropical Pacific Ocean, majority of the CSs lie in mature stage with CAF between 0.3 to 0.6, whereas, CSs in mature stage over the Atlantic Ocean have their CAF between 0.2 and 0.3. CS characteristics over the Atlantic Ocean during the Boreal summer and winter are different.
Archive Fever: Literature, Illegibility, and Historical Method
Authors: Nicolaou Argyro 
Published: July 2019

Abstract
This essay explores the allure of illegibility in the archive. The author adapts methods from literary analysis and visual art in order to decipher an inscrutable fragment from the archive of Greek Egyptian novelist Stratis Tsirkas (1911–1980): a hastily written something on a 1929 film flyer advertising the screening of two Hollywood movies at the Ciné de Paris theater in Cairo. In her attempt to render the text legible, the author reconstructs the moment of the archival fragment’s production by developing a technique called “reverse calligraphy.” This sensory engagement with the archive’s materiality leads to a series of illuminations both with regard to Tsirkas’s biography and with regard to the role of creativity in historical inquiry.