bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trading solar energy within the neighborhood: field implementation of a blockchain-based electricity market
Authors: Wörner Anselma , Meeuw Arne , Ableitner Liliane , Wortmann Felix , Schopfer Sandro , Tiefenbeck Verena 
Published: September 2019

AbstractDue to environmental and resiliency benefits, distributed energy resources (DER) are a potential solution for meeting future electricity demand, but their integration into centralized power markets on the large scale is challenging. Many practitioners argue that blockchain technology can create new market structures for DER like local peer-to-peer energy markets which foster renewable generation. To get an understanding of the status quo of the research on blockchain-based energy exchange, we conducted a systematic literature review on the existing academic articles and industry projects. This article describes the design and technical specifications of the first real blockchain-based electricity market in Switzerland derived from this literature review and outlines the implementation of this market in the real world. The findings provide valuable guidelines for the integration of DER into future sustainable energy markets.
Towards automated engineering and validation of cyber-physical energy systems
Authors: Andrén Filip Pröstl , Strasser Thomas I. , Resch Jürgen , Schuiki Bernhard , Schöndorfer Sebastian , Panholzer Georg , Brandauer Christof 
Published: September 2019

Abstract
The massive deployment of distributed generators from renewable sources in recent years has led to a fundamental paradigm change in terms of planning and operation of the electric power system. The usage of advanced automation and information and communication technology is a key element to handle these new challenges and to turn the traditional power system into a smart grid. The implementation of such complex systems solutions is associated with increasing development complexity resulting in increased engineering costs. The traditional engineering methods used for power system automation were not intended to be used for applications of this scale and complexity. However, the usage of proper methods, automation architectures, and corresponding tools holds huge optimization potential for the engineering process. Therefore, this work presents a model-based engineering and validation support system, covering the overall engineering process for smart grid applications.
Final Analysis of DeCOG-SLT Trial: No Survival Benefit for Complete Lymph Node Dissection in Patients With Melanoma With Positive Sentinel Node
Authors: Leiter Ulrike , Stadler Rudolf , Mauch Cornelia , Hohenberger Werner , Brockmeyer Norbert H. , Berking Carola , Sunderkötter Cord , Kaatz Martin , Schatton Kerstin , Lehmann Percy , Vogt Thomas , Ulrich Jens , Herbst Rudolf , Gehring Wolfgang , Simon Jan-Christoph , Keim Ulrike , Verver Danielle , Martus Peter , Garbe Claus ,   on behalf of the German Dermatologic Cooperative Oncology Group
Published: September 2019

PURPOSE We have previously reported on the 3-year results of the phase III German Dermatologic Cooperative Oncology Group trial (DeCOG; ClinicalTrials.gov identifier: NCT02434107 ) comparing distant metastasis-free survival (DMFS), recurrence-free survival (RFS), and overall survival (OS) in patients with positive sentinel lymph-node biopsy who were randomly assigned to complete lymph node dissection (CLND) or observation. Here, we report the final analysis with 72 months of median follow up. PATIENTS AND METHODS The multicenter randomized phase III trial included patients with cutaneous melanoma of the trunk and extremities who were randomly assigned (1:1) to undergo CLND or observation. DMFS was analyzed as the primary end point, and RFS, OS, and recurrences in the regional lymph node basin were secondary end points. The analysis was by intention to treat. Disease and survival information were collected quarterly. RESULTS From January 2006 to December 2014, 5,547 patients were screened to identify 1,256 with metastases in the sentinel lymph node (SLN). Of these, 483 (39%) were included: 241 in the observation arm and 242 in the CLND arm. In the final analysis, median follow up was 72 months (interquartile range, 67-77 months). No significant treatment-related difference was seen in the 5-year DMFS between the observation and CLND arms (67.6% v 64.9%, respectively; hazard ratio [HR], 1.08; P = .87). The 5-year RFS and OS also showed no difference (HR, 1.01 and 0.99, respectively). Grade 3 and 4 adverse effects occurred in 32 patients (13%) in the CLND arm; lymphedema (n = 20) and delayed wound healing (n = 5) were most common and no serious adverse events were reported. CONCLUSION The final results of the German Dermatologic Cooperative Oncology Group trial with a median follow up of 72 months showed higher event rates, but similar HRs compared with those at the 3-year analysis. These results confirm that immediate CLND in SLN-positive patients is not superior to observation in terms of DMFS, RFS, or OS and support not recommending CLND in patients with SLN metastasis.
MAPK Erk5 in Leptin Receptor‒Expressing Neurons Controls Body Weight and Systemic Energy Homeostasis in Female Mice
Authors: Horie Tetsuhiro , Park Gyujin , Inaba Yuka , Hashiuchi Emi , Iezaki Takashi , Tokumura Kazuya , Fukasawa Kazuya , Yamada Takanori , Hiraiwa Manami , Kitaguchi Yuka , Kamada Hikari , Kaneda Katsuyuki , Tanaka Tomohiro , Inoue Hiroshi , Hinoi Eiichi 
Published: September 2019

Abstract
Extracellular signal-regulated kinase 5 (Erk5), a member of the MAPK family, is specifically phosphorylated and activated by MAPK/Erk kinase-5. Although it has been implicated in odor discrimination and long-term memory via its expression in the central nervous system, little is known regarding the physiological importance of neuronal Erk5 in body weight and energy homeostasis. In the current study, systemic insulin injection significantly induced phosphorylation of Erk5 in the hypothalamus. Moreover, Erk5 deficiency in leptin receptor (LepR)‒expressing neurons led to an obesity phenotype, with increased white adipose tissue mass due to increased adipocyte size, only in female mice fed a normal chow diet. Furthermore, Erk5 deficiency in LepR-expressing neurons showed impaired glucose tolerance along with decreased physical activity, food intake, and energy expenditure. These results suggest that Erk5 controls body weight and systemic energy homeostasis probably via its expression in hypothalamic neurons in female mice, thereby providing a target for metabolic diseases such as obesity and type 2 diabetes mellitus.
Visualising three-dimensional genome organisation in two dimensions
Authors: Ing-Simmons Elizabeth , Vaquerizas Juan M. 
Published: September 2019

ABSTRACT
The three-dimensional organisation of the genome plays a crucial role in developmental gene regulation. In recent years, techniques to investigate this organisation have become more accessible to labs worldwide due to improvements in protocols and decreases in the cost of high-throughput sequencing. However, the resulting datasets are complex and can be challenging to analyse and interpret. Here, we provide a guide to visualisation approaches that can aid the interpretation of such datasets and the communication of biological results.
Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures
Authors: Ruiz García Sandra , Deprez Marie , Lebrigand Kevin , Cavard Amélie , Paquet Agnès , Arguel Marie-Jeanne , Magnone Virginie , Truchi Marin , Caballero Ignacio , Leroy Sylvie , Marquette Charles-Hugo , Marcet Brice , Barbry Pascal , Zaragosi Laure-Emmanuelle 
Published: September 2019

ABSTRACT
The upper airway epithelium, which is mainly composed of multiciliated, goblet, club and basal cells, ensures proper mucociliary function and can regenerate in response to assaults. In chronic airway diseases, defective repair leads to tissue remodeling. Delineating key drivers of differentiation dynamics can help understand how normal or pathological regeneration occurs. Using single-cell transcriptomics and lineage inference, we have unraveled trajectories from basal to luminal cells, providing novel markers for specific populations. We report that: (1) a precursor subgroup of multiciliated cells, which we have entitled deuterosomal cells, is defined by specific markers, such as DEUP1, FOXN4, YPEL1, HES6 and CDC20B; (2) goblet cells can be precursors of multiciliated cells, thus explaining the presence of hybrid cells that co-express markers of goblet and multiciliated cells; and (3) a repertoire of molecules involved in the regeneration process, such as keratins or components of the Notch, Wnt or BMP/TGFβ pathways, can be identified. Confirmation of our results on fresh human and pig airway samples, and on mouse tracheal cells, extend and confirm our conclusions regarding the molecular and cellular choreography at work during mucociliary epithelial differentiation.
Developing a phosphodiesterase-5 inhibitor assay to detect counterfeit drugs containing phosphodiesterase-5 inhibitors using spectrophotometry
Authors: Azizi Aziemah , Tengah Asrin , Petalcorin Mark I. R. 
Published: September 2019

Background: Phosphodiesterase-5 inhibitors (PDE5i) are the first line of drugs used for the treatment of erectile dysfunction. PDE5i inhibits the activities of phosphodiesterase-5 (PDE5) found in corpus cavernosum reducing production of guanosine monophosphate (GMP) that results in vasodilation of blood vessels thereby prolonging penile erection. Various counterfeit drugs adulterated with unknown levels of PDE5i pose a danger with reported undesirable adverse effects on patients. Methods: We developed an assay to detect counterfeit drugs containing PDE5i using spectrophotometry based on a colour change of malachite green from blue to green when exposed to inorganic phosphate (Pi) measured at 630 nm. Initially, a standard graph of a known Pi concentration was established ranging from 0 to 20 µM followed by a dual biochemical reaction system of converting GMP from cGMP by PDE5, generating Pi from the first reaction’s product by calf intestinal alkaline phosphatase (CIAP), and then measuring Pi using an equation derived from the generated standard curve. Dilutions of CX1A, a counterfeit drug sample adulterated with the PDE5i sildenafil, were prepared via ultrasonication and filtration for assay testing and evaluation. Results: Sil was detected from the two separate samples comprised of low and high dilutions of CX1A quantified as 0.673% and 0.407%, respectively, based on a standard curve of pure sildenafil established from 0.1 nM to 300 µM. Conclusions: This PDE5i assay that we developed has the potential to become an alternative analytical method for detecting PDE5i showing comparable results when evaluated using HPLC.
A sedução da Psicanálise nas páginas das Revistas Femininas Cláudia e Nova de 1970-1990
Authors: Borges Dulcina Tereza Bonati 
Published: September 2019

O presente trabalho visa captar os processos psicológicos subjetivos do movimento de modernização, a partir de uma pesquisa em artigos recolhidos nas Revistas Cláudia e Nova, entre as décadas de 1970-1990, tendo em vista as transformações ocorridas quanto aos valores ético-morais, nessa fase de grandes mudanças sociais. Trata-se de perceber como os discursos das Psicologias e da Psicanálise entram no campo constituído pela mídia, especificamente direcionados para orientar o comportamento feminino, erigindo-se como guia norteador na resolução dos conflitos pessoais e sexuais e da crise da identidade feminina.
PALAVRAS-CHAVE: Revistas Femininas. Modernização. Subjetivação.

ABSTRACT
The presente work aims at capturing the subjective psychological processes of the modernization movement, based on a research on articles collected in the Cláudia and Nova Magazines between the 1970s and 1990s, in view of the transformations that have occurred regarding ethical and moral values social change. It is a question of perceiving how the discourses of Psychology and Psychoanalysis enter into the field constituted by the media, specifically directed to orient the female behavior, erecting itself as guiding guide in the resolution of the personal and sexual conflicts and the crisis of the feminine identity.
KEYWORDS: Women´s Magazines. Modernization. Subjectivation.
Madames e mademoiselles nas revistas curitibanas do início do século XX
Authors: Kaminski Rosane 
Published: September 2019

RESUMO
Este artigo discute o lugar da mulher nas revistas ilustradas em Curitiba no início do século XX. Observa as principais formas pelas quais a mulher foi representada nas revistas, e pondera sobre os limites da atuação da mulher como produtora de textos e imagens para esses periódicos.
PALAVRAS-CHAVE:Revistas ilustradas. Curitiba.Mulher.

ABSTRACT
This paper examines the role of women in illustrated magazines of Curitiba city in early twentieth century. In this way, it analyses the main ways of women’s depiction in the magazines, and discusses the boundaries of women’s activities as magazine writers and illustrators.
KEYWORDS: Illustrated magazines. Curitiba. Woman
Afetos e memórias: a trajetória de Maria Clara Tomaz Machado em perspectiva
Authors: Santos e Costa Artur Nogueira 
Published: September 2019

Este texto foi escrito para ser apresentado no Seminário “Clareando caminhos: cultura popular, memórias e identidades no fazer acadêmico”, realizado na Universidade Federal de Uberlândia, em novembro de 2018, em homenagem à professora Maria Clara Tomaz Machado em razão de sua aposentadoria. Discuto elementos da trajetória de Maria Clara a partir da leitura de sua produção intelectual, com foco na questão do ofício do historiador, do patrimônio cultural e da cultura popular.
Palavras-Chave: Trajetória profissional. Memórias. Ofício do historiador.

ABSTRACT:
This text was written to be presented at the Seminar "Clearing ways: Popular Culture, Memories and Identities in Academic Achievement", held at the Federal University of Uberlândia, in November 2018, in honor of the teacher Maria Clara Tomaz Machado due to her retirement. I discuss elements of Maria Clara's trajectory from the reading of her intellectual production, focusing on the question of the office of historian, cultural heritage and popular culture.
Keywords: Professional trajectory. Memoirs. Office of the historian.
A new approach for solving Bratu’s problem
Authors: Ghomanjani Fateme , Shateyi Stanford 
Published: September 2019

Abstract
A numerical technique for one-dimensional Bratu’s problem is displayed in this work. The technique depends on Bernstein polynomial approximation. Numerical examples are exhibited to verify the efficiency and accuracy of the proposed technique. In this sequel, the obtained error was shown between the proposed technique, Chebyshev wavelets, and Legendre wavelets. The results display that this technique is accurate.
Institutional Identity
Authors: Rust Joshua 
Published: September 2019

AbstractFor some sufficiently long-standing institutions, such as the English Crown, there is no single thread, whether specified in terms of constitutive rules or assigned functions, that would connect the stages of that institution. Elizabeth II and Egbert are not connected by an unbroken chain of primogeniture and they have importantly different powers and functions. Derek Parfit famously sought to illuminate his account of personal identity by comparing a person to a club. If Parfit could use our intuitions about clubs to help motivate his neo-Lockean account of personal identity over time, which resists the idea that personal identity requires a common psychological thread, then I argue that an adapted version of his account of identity might, in turn, be reapplied to clubs and other institutions, such as the Crown.
On the Gevrey ultradifferentiability of weak solutions of an abstract evolution equation with a scalar type spectral operator on the open semi-axis
Authors: Markin Marat V. 
Published: September 2019

Abstract
Given the abstract evolution equation

$$\begin{array}{}
\displaystyle
y'(t)=Ay(t),\, t\ge 0,
\end{array}$$
with scalar type spectral operator A in a complex Banach space, found are conditions necessary and sufficient for all weak solutions of the equation, which a priori need not be strongly differentiable, to be strongly Gevrey ultradifferentiable of order β ≥ 1, in particular analytic or entire, on the open semi-axis (0, ∞). Also, revealed is a certain interesting inherent smoothness improvement effect.
Improved near-UV electroluminescence of ZnO nanorod array LEDs by coupling with a graphene plasmon layer
Authors: Zhang Cen , Qiu Yue , Liu Weizhen , Xu Haiyang , Yang Liu , Wang Chunliang , Liu Yichun 
Published: September 2019

Abstract
The development of short-wavelength light-emitting diodes (LEDs) with high emission efficiency, a fascinating research area, is still necessary because of great scientific interest and practical significance. Here, a graphene plasmon layer treated by oxygen plasma was employed into ZnO nanorod/p-GaN LEDs for a surface plasmon effect. The graphene-decorated heterojunction exhibited an approximately 4-fold improvement of ZnO ultraviolet (UV) electroluminescence (EL) intensity relative to a primitive p-n junction device. Time-resolved spectroscopy and temperature-dependent luminescence measurement indicated that the EL enhancement resulted from the coupling of ZnO excitons with graphene surface plasmons. The current research not only provides an opportunity to construct three-dimensional architecture from a vertical array of one-dimensional nanorods and a two-dimensional graphene layer, but also proposes an effective strategy to improve near-UV emission efficiency in various devices.
Crystal structure of Bis(acetato-κ2
O,O′)-bis[4-(dimethylamino)pyridine-κN]nickel(II), C18H26N4NiO4
Authors: Li Zhuang-Yu , Liu E. , Jian Fang-fang , Liang Tong-ling 
Published: September 2019

Abstract
C18H26N4NiO4, triclinic, P1̄ (no. 2), a = 7.7547(16) Å, b = 7.8666(16) Å, c = 8.2798(17) Å, α = 90.46(3)°, β = 96.24(3)°, γ = 93.25(3)°, V = 501.24(18) Å3, Z = 1, R
gt(F) = 0.0294, wR
ref(F
2) = 0.0873, T = 310 K.
Barrierefreiheit als (k)ein Qualitätskriterium in der ambulanten Gesundheitsversorgung
Authors: Hollederer Alfons 
Published: September 2019

Zusammenfassung
Barrierefreiheit in der ambulanten Gesundheitsversorgung umfasst als komplexe Intervention bauliche, personelle, organisatorische und räumliche Maßnahmen für behinderte Menschen im Sinne der UN-Behindertenrechtskonvention. Dieser Artikel exploriert, inwieweit den Menschen mit Behinderungen ein barrierefreier Zugang in der ambulanten Gesundheitsversorgung in Deutschland ermöglicht wird. Er zeigt Datendefizite bei der Erfassung von Barrierefreiheit und den Handlungs- und Forschungsbedarf auf.
Effects of a Novel Rotator Cuff Rehabilitation Device on Shoulder Strength and Function
Authors: Savitzky Jamie A. , Abrams Lindsay R. , Galluzzo Nicole A. , Ostrow Samantha P. , Protosow Tracy J. , Liu Shou-An , Handrakis John P. , Friel Karen 
Published: September 2019

Abstract
Savitzky, JA, Abrams, LR, Galluzzo, NA, Ostrow, SP, Protosow, TJ, Liu, SA, Handrakis, JP, and Friel, K. Effects of a novel rotator cuff rehabilitation device on shoulder strength and function. J Strength Cond Res 35(12): 3355–3363, 2021—The glenohumeral joint, a multiaxial ball and socket joint, has inherent instability counterbalanced by the muscular stability of the rotator cuff (RC) and connective tissue. Exercise has been shown to alleviate pain and disability arising from degenerative changes of the RC due to overuse, trauma, or poor posture. This study compared the training effects of ShoulderSphere (SS), an innovative device that uses resistance to centrifugal force, to TheraBand (TB), a traditional device that uses resistance to elasticity. Thirty-five healthy male and female adults (24.2 ± 2.4 years) were randomized into 3 groups: SS, TB, and control. Five outcomes were assessed before and after the twice-weekly, 6-week intervention phase: strength (shoulder flexion [Fx], extension [Ext], external rotation [ER], and internal rotation [IR]), proprioception (6 positions), posterior shoulder endurance (ShEnd), stability (Upper Quarter Y-Balance Test [YBal] (superolateral [YBalSup], medial [YBalMed], and inferolateral [YBalInf]), and power (seated shot put [ShtPt]). Data were analyzed using a 3 (group: SS, TB, and control) × 2 (time: pre and post) generalized estimating equation. Analyses demonstrated a main effect of time for all strength motions (p < 0.01): YBalInf (p < 0.0001), ShtPt (p < 0.05), and ShEnd (p < 0.0001) but no interaction effects of group × time. There were no main or interaction effects for proprioception. Both SS and TB groups had significant within-group increases in Ext, IR, YBalInf, and ShEnd. Only the SS group had significant increases in ER, Fx, and ShtPt. ShoulderSphere demonstrated comparable conditioning effects with TB and may afford additional strength gains in Fx and ER, and power. ShoulderSphere should be considered a viable alternative in RC conditioning.
Examining Time Perspective Orientation in Suicide Ideation and Suicide Attempts
Authors: Shahnaz Arezoo , Saffer Boaz Y. , Klonsky E. David 
Published: September 2019

Introduction: Time perspective orientation (TPO) refers to the way an individual psychologically and behaviorally connects to temporal concepts of past, present, and future. Previous studies have hypothesized that certain types of time perspectives, such as a negative orientation towards the past, predict negative psychological functioning and outcomes, including suicide risk. The current study examines whether differences in TPOs are linked to suicidal thoughts or suicidal acts using two measures of time perspective.Methods: We recruited a large online U.S.-based sample comprised of three groups: participants with (a) a history of suicide attempts (attempters; n = 107), (b) a history of suicide ideation but no history of attempts (ideators; n = 164), and (c) no history of ideation or attempts (nonsuicidal; n = 194).Results: A Positive Past (d = 0.71) and Negative Past (d = 0.89) orientation yielded large differences between individuals with a history of suicide ideation and nonsuicidal participants, where Positive Past was elevated among nonsuicidal participants and Negative Past among ideators. These differences were not accounted for by depression or anxiety. However, TPO differences between individuals with a history of suicide ideation and individuals with a history of attempts ranged from negligible to small (d range = 0.03—0.33).Discussion: The findings suggest that time perspective may be robustly associated with the development of suicide ideation, but only minimally related to suicide attempts among ideators.
A Cross-Cultural Investigation of Co-Rumination Via Cellphone Among Emerging Adults
Authors: Murdock Karla Klein , Carlucci Leonardo , Balsamo Michela 
Published: September 2019

Introduction: This study investigated cellphone-mediated co-rumination and its association with emerging adults' anxiety, depression, and social functioning. Comparisons on the basis of gender and nation of residence (United States vs. Italy) were made, and the co-rumination subcomponent of co-brooding was explored. Method: Participants included 216 undergraduate students recruited in the southeastern United States and 375 students recruited in southern Italy. Results: Co-rumination via cellphone was associated with higher levels of anxiety and depression and lower levels of social self-efficacy in the U.S. sample. Analyses of the co-brooding element of co-rumination via cellphone revealed its robust association with anxiety and depression in the U.S. sample. In contrast, among Italian emerging adults co-rumination via cellphone was not associated with anxiety or depression and it was positively associated with social well-being. Co-brooding via cellphone was not associated with anxiety or depression in the Italy sample. Discussion: Cross-cultural and gender differences in co-rumination via cellphone and psychosocial functioning are discussed.