bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Kadar Lipid Darah dan hsCRP pada Anak Obesita
Authors: Soetadji Anindita , Utari Agustini , Pratiwi Rina , Mexitalia Maria , Subagjo Hertanto W 
Published: September 2019

Latar belakang : Obesitas telah menjadi epidemi global karena prevalensi dan komplikasinya baik pada anak maupun dewasa. Meskipun aterosklerosis telah diketahui dimulai pada masa anak, tetapi sampai sekarang belum ada penanda aterosklerosis dini khususnya pada anak. Tujuan penelitian ini adalah mencari hubungan antara kadar lipid darah dengan hsCRP sebagai penanda dini aterosklerosis pada anak.
Metode : Desain penelitian adalah belah lintang. Tempat penelitan di SMP Domenico Savio, salah satu SMP di Semarang, yang telah diketahui tinggi angka obesitasnya. Dinilai indeks massa tubuh (IMT) dan persentase lemak tubuh pada murid usia 12-14 tahun, serta kadar lipid darah (kolesterol total, LDL, HDL serta trigliserida) dari darah puasa. Sampel dipilih secara acak, dihitung dengan rumus untuk uji korelasi, dibutuhkan sampel 35 anak obesitas, dan diambil 35 anak normal sebagai pembanding, maka total subyek penelitian minimal adalah 70 orang.
Hasil : Terdapat perbedaan kadar trigliserid (95%CI;0,13-0,26) dan hsCRP (95%CI;0,37-0,87) pada kelompok obesitas dan kontrol. Pada seluruh subyek, hsCRP berhubungan sedang dengan IMT (r=0,445;p< 0,05) dan persen lemak tubuh (r=0,44;p<0,05) serta hubungan lemah antara kadar HDL dan hsCRP (r=-0,227; p<0,05).
Simpulan : Kadar hsCRP akan meningkat bila terjadi peningkatan IMT dan persentase lemak tubuh, sedangkan kadar HDL kolesterol bersifat protektif terhadap peningkatan hsCRP
Penanganan Kesehatan pada Tanggap Darurat Bencana Erupsi Gunung Merapi
Authors: Martono Setyo , Ratnawati Retty , Setyoadi Setyoadi 
Published: September 2019

Latar belakang : Bencana erupsi Gunung Merapi tahun 2010 di wilayah Jawa Tengah mengakibatkan jatuhnya banyak korban bencana yang mengalami dampak fisik dan dampak psikologis. Perawat tim kesehatan bencana melakukan tindakan awal pada upaya triage dan evakuasi korban bencana. Upaya triage dan evakuasi bertujuan untuk menyelamatkan korban bencana sebanyak-banyaknya, mencegah kematian dan kecacatan. Perawat tim kesehatan bencana melakukan proses triage dengan metote berbeda dari proses triage yang dilakukan di rumah sakit. Penelitian ini bertujuan untuk mengeksplorasi pengalaman perawat dalam penanganan korban bencana pada tanggap darurat erupsi Gunung Merapi di Jawa Tengah.
Metode : Penelitian ini merupakan penelitian kualitatif dengan desain fenomenologi interpretatif. Partisipan dalam penelitian ini sebanyak enam orang perawat yang bertugas di RSUP Dr. Kariadi dan RS Roemani Semarang. Pengambilan data dilakukan dengan wawancara semi terstruktur. Data ditranskrip dan dianalisis menggunakan langkah-langkah dari Colaizzi.
Hasil : Penelitian ini menghasilkan enam tema yaitu senang menolong orang lain, kesiapan perawat dalam menghadapi bencana, komunikasi perawat dalam bencana, prioritas penanganan korban bencana, upaya perawatan korban bencana, dan bersyukur pada Alloh SWT.
Simpulan : Perawat kesehatan bencana melakukan tindakan awal penanganan korban pada upaya triage dan evakuasi dengan cara yang berbeda dibandingkan cara yang dilakukan di rumah sakit. Perawat melakukan upaya triage dan evakuasi secara simultan dengan memprioritaskan penanganan pada kelompok rentan. Kelompok rentan harus di prioritaskan karena mereka rentan terhadap kematian, penyakit, dan mempunyai ketergantungan yang tinggi pada bantuan orang lain serta pemenuhan kebutuhan korban sendiri. Penanganan awal perawat pada upaya triage dan evakuasi pada kelompok rentan akan dapat menyelamatkan korban bencana yang banyak.
TEGANGAN PULLOUT DAN PEREKAAN PERMUKAAN PADA SERAT DAUN PANDAN DURI (PANDANUS TECTORIUS) – RESIN POLYESTER
Authors: Riyanto Achmat , Respati Sri Mulyo Bondan , Syafa’at Imam 
Published: September 2019

Dewasa ini perkembangan teknologi yang semakin maju menyebabkan kebutuhan material komposit semakin meningkat, salah satunya teknologi material komposit berpenguat serat alam, serat daun pandan duri berpotensi untuk dijadikan sebagai bahan baku material komposit. Penelitian ini bertujuan untuk mengetahui kekuatan tarik dan foto mikro serat daun pandan duri dengan perlakuan perendaman air laut. Pengujian pull-out juga dilakukan untuk mengetahui tegangan geser serat dengan matrik resin polyester. Serat daun pandan duri yang direndam kedalam air laut, dengan variasi waktu 0, 1, 2, 3, dan 4 minggu. Hasil yang diperoleh dari uji tarik serat tunggal menunjukkan bahwa pada perendaman selama 2 minggu memiliki nilai kekuatan tarik yang optimal sebesar 28,65 Mpa, hal ini juga terbukti dari hasil foto mikro serat yang menunjukan kepadatan sub celahnya. Sedangkan kekuatan tarik serat tanpa perlakuan perendaman dan perendaman selama 1, 3, dan 4 minggu berturut-turut adalah 22,57 MPa, 24,43 MPa, dan 18,96 MPa. Kemudian pada pengujian pull out nilai tegangan geser tertinggi sebesar 1,33 MPa lebih tinggi dibanding tanpa perlakuan perendaman dan perendaman air laut 1, 3, dan 4 minggu berturut-turut yaitu sebesar 0,09 MPa, 1,11 MPa, 1,21 MPa, dan 1,07 MPa. Dari hasil penelitian yang dilakukan, serat daun pandan duri mempunyai kompatibilitas yang baik dengan resin polyester setelah diberi perlakuan perendaman air lautKata kunci: serat daun pandan duri, resin uji pull-out, kompatibilitas
A Study of Students’ Motivation in Using the Mobile Arc Welding Learning App
Authors: Najwa Rusli Farhatun , Zulkifli Abdul Nasir , Bin Saad Mohd. Nizam , Md.Yussop Yussalita 
Published: September 2019

Welding is an introductory core subject that is taught in every mechanical engineering programs at all polytechnics in Malaysia. Normally students will learn the theoretical concepts of welding in the class followed by instruction based training in the workshop. However, students have difficulty to follow everything that has been taught in the class in a limited time. Welding is dangerous for beginners and the welding environments are harmful and injurious to the health. In this paper, we introduce Mobile Arc Welding Learning (MAWL) app, a new approach for learning arc welding that incorporates mobile technology and enhanced with augmented reality (AR). The aim of this app is to enhance the contents used in arc welding learning materials used in the conventional learning by visualizing the information through the use of text, images, videos and 3D models. The MAWL app covers topics related to safety in welding, components of welding and steps in welding. The students can use the app to learn about welding on their own anytime and anywhere. The potential of using the MAWL app for welding learning among the polytechnic students has been investigated, specifically focusing on ease of use, learnability, satisfaction, usefulness, motivation and engagement. The results of the evaluation indicate that the users strongly agreed on ease of use, learnability, satisfaction, usefulness and motivation, while they agreed on engagement. These prove that the MAWL app has the potential to contribute to students’ welding learning through interactive and accessible information that satisfies them.
Osteoarthritis Prevalence in Retired National Football League Players With a History of Ankle Injuries and Surgery
Authors: Song Kyeongtak , Wikstrom Erik A. , Tennant Joshua N. , Guskiewicz Kevin M. , Marshall Stephen W. , Kerr Zachary Y. 
Published: September 2019

Context
Ankle injuries are common at all levels of American football, and retired National Football League (NFL) players have a high prevalence of osteoarthritis (OA), but little is known about how ankle injuries influence OA prevalence and daily activities in this population or how surgical interventions for such injuries alter the risk of OA.

Objective
To examine (1) the association of ankle-injury history with OA prevalence, (2) the association of surgical intervention after ankle injury with OA prevalence, and (3) the relationships among ankle injuries, reported OA, and daily activities in retired NFL players.

Design
Case-control study.

Setting
Survey.

Patients or Other Participants
Data from the Retired NFL Players General Health Survey.

Main Outcome Measure(s)
We created a 7-category main exposure variable that differentiated respondents by football-related ankle injury and surgical intervention. Multivariable binomial regression models were used to estimate prevalence ratios and 95% confidence intervals. Among those reporting OA, we examined the distribution of responses regarding whether OA affected daily activities.

Results
Among the 2446 respondents, 920 participants experienced OA in any joint during their lifetime. Compared with those reporting no ankle injuries, the prevalence of OA was higher among those with a history of ankle injury. Also, the prevalence of OA was higher among those who had undergone surgery versus those who had not. The number of retired NFL players who reported that OA often affected their daily activities increased with the number of ankle injuries.

Conclusions
Among former NFL players, a history of ankle injury increased the prevalence of OA. More ankle injuries increased the probability that OA negatively affected daily activities. Future prospective research is needed to better determine the influence of surgical intervention at the ankle or foot on OA.
On the Coarse Geometry of James Spaces
Authors: Lancien Gilles , Petitjean Colin , Procházka Antonin 
Published: September 2019

AbstractIn this note we prove that the Kalton interlaced graphs do not equi-coarsely embed into the James space${\mathcal{J}}$nor into its dual${\mathcal{J}}^{\ast }$. It is a particular case of a more general result on the non-equi-coarse embeddability of the Kalton graphs into quasi-reflexive spaces with a special asymptotic structure. This allows us to exhibit a coarse invariant for Banach spaces, namely the non-equi-coarse embeddability of this family of graphs, which is very close to but different from the celebrated property${\mathcal{Q}}$of Kalton. We conclude with a remark on the coarse geometry of the James tree space${\mathcal{J}}{\mathcal{T}}$and of its predual.
Effect of ultraviolet on vitamin D and quality of life in postmenopausal women: a randomized controlled study
Authors: Aleshmawy Mohamed Dina Mahmoud , Okeil Fahima Metwally , Yousef Amel Mohamed , Mustafa Mohammed Hassan , Hamada Hamada Ahmed , Saab Ibtissam M. 
Published: September 2019

IntroductionTo determine the influence of ultraviolet radiation on vitamin D plasma levels and quality of life in postmenopausal women with vitamin D deficiency.MethodsIn a single-blinded randomized controlled trial design, 30 postmenopausal women were chosen suffering from a progressive, generalized muscle weakness, associated with decrease in physical function and poor quality of life. The subjects were aged 45–65 years and were randomly assigned into group A, treated by ultraviolet radiation in addition to regular aerobic exercises; and group B, receiving solely aerobic exercises. All participants had 3 sessions per week for 3 months. Outcome measures determined before and after the 3 months of intervention were vitamin D level and the results of the short form (SF-36) of a specific quality of life questionnaire.ResultsA significant increase in vitamin D was observed along with an improvement in quality of life in group A compared with group B after the treatment period.ConclusionsThe 12-week program of ultraviolet radiation in addition to regular aerobic exercises yielded more improvement in vitamin D and quality of life than aerobic exercises alone in the management of postmenopausal chronic musculoskeletal disorders.
Strongyloidiasis in North Queensland: re‐emergence of a forgotten risk group?
Authors: Yiannakou John , Croese John , Ashdown Leslie R , Prociv Paul 
Published: September 2019

ObjectiveTo describe the clinical presentation, diagnosis and management of strongy‐loidiasis in northern Queensland, and to identify predisposing factors for this infection.DesignA five‐year retrospective study of medical records of all cases diagnosed in a regional hospital microbiology laboratory, with follow‐up by interview where possible.SettingThe Townsville General Hospital.PatientsA total of 14 cases of strongy‐loidiasis were identified, with patients ranging in age from 7 months to 59 years.ResultsInfected patients included nine Aborigines and two Vietnamese refugees, both high‐risk groups. Of three Caucasians diagnosed, one was a war veteran, but the other two did not have significant travel histories; all three had lived or worked under insanitary conditions. In only one case was strongyloidiasis suspected; in most, it was diagnosed because of diarrhoea or blood eosinophilia which could not be related to the presenting illness. Thiabendazole treatment was effective in most cases.ConclusionIn northern Australia, strongy‐loidiasis can be acquired locally by Caucasians who live in unhygienic circumstances. It should be suspected in any person with unexplained abdominal pain, diarrhoea, cutaneous symptoms or blood eosinophilia, and the laboratory must be informed of the provisional diagnosis.
Isosporiasis in the Aboriginal population of Queensland
Authors: Prociv Paul , Luke Russell , Quayle Philip 
Published: September 2019

ObjectiveTo report on the endemicity of Isospora belli in Queensland.DesignA 10‐year retrospective survey of data from routine parasitological surveillance of Queensland Aboriginal communities, by microscopic examination of preserved faecal specimens.SettingThe Aboriginal Health Programme of the Queensland Department of Health and Medical Services.PopulationChildren under 15 years of age from all the Aboriginal communities of Queensland.ResultsOocysts of,. belli were detected in 33 (0.2%) of a total of 17 642 faecal samples examined.ConclusionIsosporiasis is endemic in the Queensland Aboriginal population. It is likely to be more common than indicated, because the infection is difficult to diagnose, and the techniques used to identify the organism were not particularly sensitive. It is predicted that isosporiasis will be recognised with increasing frequency as a cause of diarrhoea in Aboriginal and white Australians who develop AIDS.
Prenatal diagnosis and successful intrauterine treatment of a female fetus with 21‐hydroxylase deficiency
Authors: Haan Eric A , Penfold James L , Richards Robert I , Serjeantson Susan W , Rollond A Kenneth , Norman Robert , Antonis Peter 
Published: September 2019

ObjectiveTo present the first reported Australian case of prenatal treatment of a female fetus with congenital adrenal hyperplasia resulting from 21‐hydroxylase deficiency.Clinical featuresA couple whose son had congenital adrenal hyperplasia resulting from 21‐hydroxylase deficiency sought prenatal diagnosis and treatment in their next pregnancy.InterventionMaternal treatment with dexamethasone was commenced at seven weeks' gestation to suppress androgen production by the fetal adrenal glands and prevent virilisation of an affected female fetus. At ten weeks' gestation chorionic villus sampling demonstrated a female fetus, who was shown subsequently to be affected by means of a linkage method in which probes to HLA genes DQA and DRB were used as markers for the 21‐hydroxylase genes.Increased17‐hydroxyprogesterone and androstenedione immunoactivity in amniotic fluid Obtained at 14.5 weeks confirmed the fetus to be affected and demonstrated incomplete suppression of fetal adrenal androgen production. Dexamethasone was continued to term and maintained suppression of the fetal and maternal adrenal glands.OutcomeThe infant was born with normal female genitalia. Growth retardation was present but the relationship between this and the dexamethasone treatment remains uncertain. The mother had excessive weight gain during pregnancy.ConclusionDexamethasone treatment commenced in the first weeks of pregnancy can prevent or reduce virilisation of female fetuses with congenital adrenal hyperplasia resulting from 21‐hydroxylase deficiency.
The Nose‐To‐Brain Transport of Polymeric Nanoparticles Is Mediated by Immune Sentinels and Not by Olfactory Sensory Neurons
Authors: Kumarasamy Murali , Sosnik Alejandro 
Published: September 2019

AbstractThe nose‐to‐brain (N‐to‐B) transport mechanism of nanoparticles through the olfactory epithelium (OE) is not fully understood. Most research utilized nasal epithelial cell models completely deprived of olfactory cells. Aiming to shed light into key cellular pathways, in this work, for the first time, the interaction of polymeric nanoparticles in a 17–483 nm size range and with neutral and negatively and positively charged surfaces with primary olfactory sensory neurons, cortical neurons, and microglia isolated from olfactory bulb (OB), OE, and cortex of newborn rats is investigated. After demonstrating the good cell compatibility of the different nanoparticles, the nanoparticle uptake by confocal laser scanning fluorescence microscopy is monitored. Our findings reveal that neither olfactory nor forebrain neurons internalize nanoparticles. Conversely, it is demonstrated that olfactory and cortical microglia phagocytose the nanoparticles independently of their features. Overall, our findings represent the first unambiguous evidence of the possible involvement of microglia in N‐to‐B nanoparticle transport and the unlikely involvement of neurons. Furthermore, this approach emerges as a completely new experimental tool to screen the biocompatibility, uptake, and transport of nanomaterials by key cellular players of the N‐to‐B pathway in nanosafety and nanotoxicology and nanomedicine.
NaCl Nanoparticles as a Cancer Therapeutic
Authors: Jiang Wen , Yin Lei , Chen Hongmin , Paschall Amy Victoria , Zhang Liuyang , Fu Wenyan , Zhang Weizhong , Todd Trever , Yu Kevin Shengyang , Zhou Shiyi , Zhen Zipeng , Butler Michael , Yao Li , Zhang Feng , Shen Ye , Li Zibo , Yin Amelia , Yin Hang , Wang Xianqiao , Avci Fikri Y. , Yu Xiaozhong , Xie Jin 
Published: September 2019

AbstractMany inorganic nanoparticles are prepared and their behaviors in living systems are investigated. Yet, common electrolytes such as NaCl are left out of this campaign. The underlying assumption is that electrolyte nanoparticles will quickly dissolve in water and behave similarly as their constituent salts. Herein, this preconception is challenged. The study shows that NaCl nanoparticles (SCNPs) but not salts are highly toxic to cancer cells. This is because SCNPs enter cells through endocytosis, bypassing cell regulations on ion transport. When dissolved inside cancer cells, SCNPs cause a surge of osmolarity and rapid cell lysis. Interestingly, normal cells are much more resistant to the treatment due to their relatively low sodium levels. Unlike conventional chemotherapeutics, SCNPs cause immunogenic cell death or ICD. In vivo studies show that SCNPs not only kill cancer cells, but also boost an anticancer immunity. The discovery opens up a new perspective on nanoparticle‐based therapeutics.
Early spring warming may hasten leaf emergence in Erythronium americanum
Authors: Tessier Jack T. 
Published: September 2019

PremiseClimate change is making spring arrive earlier than in the past, causing some species to alter the timing of their spring activities. This study addressed whether Erythronium americanum Ker Gawl. (trout lily), a common spring ephemeral, can emerge earlier if exposed to early spring warming.MethodsI collected corms of Erythronium americanum in the fall, overwintered them in soil, and exposed them to warming in either mid (early treatment) or late (late treatment) February. The timing of leaf emergence was monitored and compared between treatments.ResultsLeaves exposed to early warming emerged earlier than those in the late treatment. Bud break happened closer to date of exposure to warming in the late treatment than in the early treatment.ConclusionsSpring ephemerals may be able to produce leaves early in response to early spring warming induced by climate change. Risk of late frost and eventual shading by the canopy may limit the duration of a potentially extended growing season.
Regioselective One‐Pot Synthesis of 3‐Fluoro‐Imidazo[1,2‐a]pyridines from Styrene
Authors: Said Madhukar S. , Mishra Ankita , Pandole Satish , Nayak Rashmi A. , Kumar Pradeep , Gajbhiye Jayant M. 
Published: September 2019

AbstractA one‐pot synthesis of C‐3 fluorinated imidazopyridines (F‐IMPY) is reported under the additive‐free conditions from commercially available styrene and 1‐fluoropyridinium tetrafluoroborate as a fluorine source. The substrate styrene undergoes keto‐bromination/condensation/fluorination transformation in three sequential steps to furnish F‐IMPY. This one‐pot synthesis method exhibits broad substrate scope and good functional group tolerance with a good yield (up to 82%).
Characterization of inflammation and insulin resistance in high‐fat diet‐induced male C57BL/6J mouse model of obesity
Authors: Avtanski Dimiter , Pavlov Valentin A. , Tracey Kevin J. , Poretsky Leonid 
Published: September 2019

AbstractBackgroundAnimal models of diet‐induced obesity (DIO) are commonly used in medical research for mimicking human diseases. There is no universal animal model, and careful evaluation of variety of factors needs to be considered when designing new experiments. Here, we investigated the effect of 9 weeks high‐fat diet (HFD) intervention, providing 60% energy from fat, on parameters of inflammation and insulin resistance in male C57BL/6J mice.MethodsSix weeks old mice were initiated on regular diet (RD) or HFD providing 60 kcal energy from fat for 9 weeks. Fasting blood glucose levels were measured by glucometer, and fasting plasma levels of insulin and proinflammatory cytokines by Luminex assay. Insulin sensitivity was evaluated by using QUICKI and HOMA2 indexes.ResultsHFD mice showed ~ 40% higher body weight and ~ 20% larger abdominal circumference, due to an increase in the white adipose tissue mass. Liver examination revealed increased size and higher hepatic lipid accumulation in livers from HFD mice compared to their RD counterparts. Animals from the HFD group were characterized with significantly higher presence of crown‐like structures (CLS) in WAT and higher plasma levels of proinflammatory cytokines (TNF‐α, IL‐6, leptin, MCP‐1, PAI‐1, and resistin). HFD‐fed mice also demonstrated impaired insulin sensitivity (lower QUICKI, higher HOMA‐insulin resistance (HOMA‐IR), and lower HOMA‐percent sensitivity (HOMA‐%S)) index values.ConclusionMale C57BL/6J mice on 9 weeks HFD providing 60 kcal energy from fat display impaired insulin sensitivity and chronic inflammation, thus making this DIO mouse model appropriate for studies of early stages of obesity‐related pathology.
Variation of Aluminium Distribution in Small‐Sized ZSM‐5 Crystals during Desilication
Authors: Li Teng , Roy Kanak , Krumeich Frank , Artiglia Luca , Huthwelker Thomas , van Bokhoven Jeroen A. 
Published: September 2019

AbstractHollow ZSM‐5 zeolites of size below one micrometer can be produced by desilication of crystals with aluminium zoning. The parent crystals have a core–shell structure: the core part has nearly no aluminium, whereas the aluminium content in the shell increases when extending to exterior surface. Transmission electron microscopy confirmed the preservation of the crystalline shell after base leaching, but could not identify its subtle change. An increase of the Si/Al ratio of the surface was detected upon leaching the parent material to form the hollow zeolite by using ambient pressure X‐ray photoelectron spectroscopy and infrared spectroscopy of substituted alkylpyridines. 27Al MAS NMR showed that base leaching results in a reduced percentage of distorted tetrahedrally coordinated aluminium. The reprecipitation of dissolved species occurs and tetrahedrally coordinated tin atoms can thus be introduced to the shell framework. Overall, the formation of hollow ZSM‐5 zeolites by desilication involves not only the removal of silicon‐rich core, but also a reduced percentage of exterior aluminium‐related acid sites, which should be considered while using hollow zeolites in acid‐catalyzed reactions.