bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential of Brand Personality: Attachment Styles as Moderator
Authors: Tuan LO Ying , Tat Huam Hon , Shamsuddin Ahmad Sharifuddin , Rasli Amran Md , Jusoh Ahmad 
Published: June 2018

The purpose of this paper is to investigate the effect of consumer’s attachment styles as a moderator in the impact of brand personality on its brand attachment. This research investigated the preferred brand personality of anxious and avoidant attachment consumer, their likelihood to be attached to that brand and how they respond to any changes in brand personality. A total of 300 students were surveyed. Their attachment style and their response towards sincere and exciting personality and its brand attachment were assessed. Empirical study shows that anxious attachment style consumer preferred sincere brand personality, tends to be attached with it and did not respond to any changes in brand personality. Avoidant attachment style people on the other hand have a stronger relationship with the exciting brand personality, are not likely to be attached to it and will respond to changes in brand personality. This study implies that marketers should get to know their targeted market’s attachment style prior coming out with the suitable brand personality.
A Framework for the Strategic Management of Information Technology
Authors: Al Wazzan Dhiya Abdullah 
Published: June 2018

The complementary between IT as a competitive factor and strategic management is very important for gaining competitive advantages. This paper explores factors related to strategy and IT that should be considered for the strategic analysis of IT as a competitive factor, and proposes a framework for Strategic Technology Management (STM). The research is conducted by means of quantitative and qualitative analysis of data. The framework is expanded and validated through inference to findings of large and small to medium-sized enterprises through interviews, finally ending on theory matching. The results of the analysis show that the strategic management of information technology is a continuous process of evaluation and change and that the alignment between factors such as competitive environment, competitive strategies (business and IT strategies), competitive outcome, and competitive factors gain competitive advantages for industrial companies.
Exploring the Contributions and Challenges of Amhara Development Association to Community Development
Authors: Belay Degwale 
Published: June 2018

This study considers the challenges and contribution of Amhara Development Association (ADA) to the development of Enemay community, Ethiopia. Drawing up on the findings of a qualitative research study, this article argue that despite local civil society organizations contribute to community development, the development could not be effective and less recognized by the targeted community unless participatory. ADA has made some contributions for the community in its intervention areas of education and health though the community did not recognize the contributions. This is due to the challenges that faced ADA which include lack of adequate and permanent employees, lack of community awareness, ADA affiliation to political organization of a nation, lack of finance, top down approach of service delivery, and lack of trust and accountability. Due to these challenges, ADA was less successful to bring community development.
The Potential Impact of Family Life Education and Lay Counselor Training on Poverty in Developing Countries: The Example of India
Authors: Carson David K , Chowdhury Aparajita 
Published: June 2018

Approximately one third of the world's 1.2 billion poorest people on earth live in India. It is home to more people living in poverty than any other country in the world. Although overall poverty rates in India have decreased in the past several decades because of India's emphasis on poverty reduction and community development since independence, the number of people at or below the poverty line remains in the hundreds of millions. Poverty in India, as in many developing countries, is not just the absence of income but the presence of an ongoing state of helplessness, hopelessness, powerlessness, inequality, and marginalization of the poor. This article examines how Lay Counselor Training and Family Life Education can have a potentially powerful and long-lasting impact on the socio-economic development of individuals, families, and communities in India. The authors highlight how professionally trained Indian counselors and family life educators, in cooperation with NGO's and professionals from other areas of the world, can help reduce poverty and enhance healthy human development through the training of lay persons in both rural and urban areas, and how these efforts can, in turn, potentially augment the economic conditions of families and communities. These effects become mutually reinforcing since the economic development of families and communities is also likely to enhance the mental and emotional health of family members and the overall resilience of the family. Hence, a multimodal approach to poverty reduction is needed. In this article India serves as an example for other developing countries.
Otopathologic Changes in the Cochlea following Head Injury without Temporal Bone Fracture
Authors: Ishai Reuven , Knoll Renata M. , Chen Jenny X. , Wong Kevin , Reinshagen Katherine L. , Nadol Joseph B. , Remenschneider Aaron K. , Jung David H. , Kozin Elliott D. 
Published: June 2018

ObjectiveHearing loss following temporal bone (TB) fracture may result from direct transection of the middle and inner ear. The pathophysiology of hearing loss due to head injury without TB fracture, however, is not well understood. Few reports describe otopathologic findings. Herein, we investigate the pathologic findings of patients who sustained a head injury without evidence of a TB fracture.Study DesignOtopathology study.SettingOtopathology laboratory.SubjectsSubjects with a history of head injury without TB fracture.MethodsThe TBs of patients with head injury were evaluated by light microscopy. Inner ear anatomy was evaluated, including counts of spiral ganglion cells (SGCs), hair cells, pillar cells, atrophy of the stria vascularis, and the presence of endolymphatic hydrops. SGC counts were compared with those of historical age‐matched controls.ResultsAll cases (N = 6 TBs) had evidence of inner ear pathology. Of the 6 cases, 2 (33%) had severe loss of hair cells in all 3 turns of the cochlea, and 4 (67%) cases demonstrated moderate to severe loss at the basal turn of the cochlea. Four cases had scattered atrophy of the stria vascularis, and 3 (50%) had cochlear hydrops. The number of total SGCs was decreased, with an average 53% loss (range, 25%‐79%) as compared with controls. The SGC count loss was evenly distributed along Rosenthal's canal.ConclusionsPatients with a history of head injury without TB fracture demonstrate inner ear pathology. Further studies are necessary to determine if otopathology findings are directly attributable to trauma.
Altered cortical excitability in persistent idiopathic facial pain
Authors: Galhardoni Ricardo , Ciampi de Andrade Daniel , Puerta Mariana YT , Brunoni Andre R , Varotto Bruna LR , de Siqueira José TT , Teixeira Manoel J , Siqueira Silvia RDT 
Published: June 2018

Introduction Persistent idiopathic facial pain is a refractory and disabling condition of unknown mechanism and etiology. It has been suggested that persistent idiopathic facial pain patients have not only peripheral generators of pain, but also central nervous system changes that would contribute to the persistence of symptoms. We hypothesized that persistent idiopathic facial pain would have changes in brain cortical excitability as measured by transcranial magnetic stimulation compared to healthy controls. Methods Twenty-nine persistent idiopathic facial pain patients were compared to age- and sex-matched healthy controls and underwent cortical excitability measurements by transcranial magnetic stimulation applied to the cortical representation of the masseter muscle of both hemispheres. Single-pulse stimulation was used to measure the resting motor threshold and suprathreshold motor-evoked potentials. Paired-pulse stimulation was used to assess short intracortical inhibition and intracortical facilitation. Clinical pain and associated symptoms were assessed with validated tools. Results Spontaneous pain was found in 27 (93.1%) and provoked pain was found in two (6.9%) persistent idiopathic facial pain patients. The motor-evoked potentials at 120% and 140% were significantly lower for both hemispheres compared to controls. Persistent idiopathic facial pain patients had lower short-interval intracortical inhibition compared with controls. These changes were correlated with some aspects of quality of life, and higher mood symptoms. These neurophysiological alterations were not influenced by analgesic medication, as similar changes were observed in patients with or without central-acting drugs. Conclusions Persistent idiopathic facial pain is associated with changes in intracortical modulation involving GABAergic mechanisms, which may be related to certain aspects of the pathophysiology of this chronic pain condition. Trial registration: NTC01746355.
Meta-Analysis of the Effects of Exercise Training on Markers of Metabolic Syndrome in Solid Organ Transplant Recipients
Authors: Li Caixia , Xu Jianming , Qin Wei , Hu Yan , Lu Huijuan 
Published: June 2018

Background: The markers of metabolic syndrome can prompt the development of metabolic syndrome and are associated with worse graft function among transplant recipients. Studies have shown that exercise might be effective in reducing incidence rate of metabolic syndrome components in nontransplant patients. However, there is no sufficient evidence to determine whether exercise training is safe or effective for markers of metabolic syndrome among solid organ transplant recipients. Objective: To evaluate the safety and efficacy of exercise training programs for risk markers of metabolic syndrome and to further evaluate its long-term effects in solid organ transplant recipients. Methods: We systematically reviewed all randomized trials comparing the outcomes of exercise training in organ transplant recipients. The Cochrane Library, Joanna Briggs Institute EBP Database, PubMed, Embase, Web of Science Core Collection, ProQuest Health & Medical Complete, and SinoMed databases were searched to June 2017. The meta-analysis was conducted using RevMan 5.3. Results: In total, 13 eligible trails involving 464 patients were included. Recipients who engaged in an exercise program after transplantation showed significant reductions in fasting blood glucose, diastolic blood pressure, triglycerides, and body mass index and a significant increase in high-density lipoprotein. But found no significant changes in new-onset diabetes, systolic blood pressure, total cholesterol, or low-density lipoprotein. Conclusion: Exercise training may be a promising intervention for markers of metabolic syndrome in transplant recipients. Further research is required to determine essential aspects of exercise according to organ transplantation type for effects on markers of metabolic syndrome.
A Prospective Observational Study of Anesthesia-Related Adverse Events and Postoperative Complications Occurring During a Surgical Mission in Madagascar
Authors: White Michelle C. , Barki Brian J. , Lerma Stephen A. , Couch Sarah Kate , Alcorn Dennis , Gillerman Richard G. 
Published: June 2018

BACKGROUND:Two-thirds of the world’s population lack access to safe anesthesia and surgical care. Nongovernmental organizations (NGOs) play an important role in bridging the gap, but surgical outcomes vary. After complex surgeries, up to 20-fold higher postoperative complication rates are reported and the reasons for poor outcomes are undefined. Little is known concerning the incidence of anesthesia complications. Mercy Ships uses fully trained staff, and infrastructure and equipment resources similar to that of high-income countries, allowing the influence of these factors to be disentangled from patient factors when evaluating anesthesia and surgical outcomes after NGO sponsored surgery. We aimed to estimate the incidence of anesthesia-related and postoperative complications during a 2-year surgical mission in Madagascar.METHODS:As part of quality assurance and participation in a new American Society of Anesthesiologists Anesthesia Quality Institute sponsored NGO Outcomes registry, Mercy Ships prospectively recorded anesthesia-related adverse events. Adverse events were grouped into 6 categories: airway, cardiac, medication, regional, neurological, and equipment. Postoperative complications were predefined as 16 adverse events and graded for patient impact using the Dindo-Clavien classification.RESULTS:Data were evaluated for 2037 episodes of surgical care. The overall anesthesia adverse event rate was 2.0% (confidence interval [CI], 1.4–2.6). The majority (85% CI, 74–96) of adverse events occurred intraoperatively with 15% (CI, 3–26) occurring in postanesthesia care unit. The most common intraoperative adverse event, occurring 7 times, was failed regional (spinal) anesthesia that was due to unexpectedly long surgery in 6 cases; bronchospasm and arrhythmias were the second most common, occurring 5 times each. There were 217 postoperative complications in 191 patients giving an overall complication rate of 10.7% (CI, 9.3–12.0) per surgery and 9.4% (CI, 8.1–10.7) per patient. The most common postoperative complication was unexpected return to the operating room and the second most common was surgical site infection (39.2%; CI, 37.0–41.3 and 33.2%; CI, 31.1–35.3 of all complications, respectively). The most common (42.9%; CI, 40.7–45.1) grade of complication was grade II. There was 1 death.CONCLUSIONS:This study adds to the scarce literature on anesthesia outcomes after mission surgery in low- and middle-income countries. We join others in calling for an international NGO anesthesia and surgical outcome registry and for all surgical NGOs to adopt international standards for the safe practice of anesthesia.
Postoperative Cognitive Dysfunction and Noncardiac Surgery
Authors: Evered Lisbeth A. , Silbert Brendan S. 
Published: June 2018

Postoperative cognitive dysfunction (POCD) is an objectively measured decline in cognition postoperatively compared with preoperative function. POCD has been considered in the anesthetic and surgical literature in isolation of cognitive decline which is common in the elderly within the community and where it is labeled as mild cognitive impairment, neurocognitive disorder, or dementia. This narrative review seeks to place POCD in the broad context of cognitive decline in the general population. Cognitive change after anesthesia and surgery was described over 100 years ago, initially as delirium and dementia. The term POCD was applied in the 1980s to refer to cognitive decline assessed purely on the basis of a change in neuropsychological test results, but the construct has been the subject of great heterogeneity. The cause of POCD remains unknown. Increasing age, baseline cognitive impairment, and fewer years of education are consistently associated with POCD.
In geriatric medicine, cognitive disorders defined and classified as mild cognitive impairment, neurocognitive disorder, and dementia have definitive clinical features. To identify the clinical impact of cognitive impairment associated with the perioperative period, POCD has recently been redefined in terms of these geriatric medicine constructs so that the short-, medium-, and long-term clinical and functional impact can be elucidated. As the aging population present in ever increasing numbers for surgery, many individuals with overt or subclinical dementia require anesthesia. Anesthesiologists must be equipped to understand and manage these patients.
Postexercise Hemodynamic Responses in Lean and Obese Men
Authors: ZEIGLER ZACHARY S. , SWAN PAMELA D. , BUMAN MATTHEW P. , MOOKADAM FAROUK , GAESSER GLENN A. , ANGADI SIDDHARTHA S. 
Published: June 2018

ABSTRACT

Purpose
We assessed resting central/peripheral blood pressure (BP), postexercise BP, and hemodynamic responses (stroke volume, cardiac output, and systemic vascular resistance) after acute exercise and 2 wk of aerobic training in lean and centrally obese men matched for BP.

Methods
Eight lean (body mass index < 25 kg·m−2, visceral fat = 279 ± 224 cm3) and eight centrally obese (body mass index > 30 kg·m−2, visceral fat = 1471 ± 374 cm3) men performed six training sessions (3 d·wk−1 for 40 min at 65%–70% HRmax). Resting BP and hemodynamic measurements were obtained at baseline, after exercise for 60 min, and at 24 h and 48 h after the last training session.

Results
Postexercise brachial and central systolic BP (SBP) and mean arterial BP decreased 3–4 mm Hg below resting in lean (P < 0.001) and increased by 3 mm Hg in obese (P < 0.02). Posttraining resting brachial/central SBP were reduced by 3–4 mm Hg only in lean men (P < 0.05). Pretraining postexercise hypotension was significantly correlated with the training-induced change in resting brachial SBP at 48 h (r = 0.58, P = 0.02), but not at 24 h (r = 0.38, P = 0.15). Similar correlations were observed between acute reductions in central SBP and central SBP at 24 h (r = 0.43, P = 0.09) and 48 h (r = 0.54, P = 0.03) posttraining.

Conclusions
In contrast to the consistent results for lean men, postexercise hypotension was not observed in centrally obese men, and resting SBP was not reduced after a short aerobic training program. Considerable individual variation in postexercise BP response among obese men may have implications for design of exercise interventions to lower BP in these individuals.
Predicting Ground Reaction Force from a Hip-Borne Accelerometer during Load Carriage
Authors: NEUGEBAUER JENNIFER M. , LAFIANDRA MICHAEL 
Published: June 2018

ABSTRACT

Introduction
Ground reaction forces (GRF) during load carriage differ from unloaded walking. Methods to quantify peak vertical GRF (pGRFvert) of Soldiers walking with loads outside of a laboratory are needed to study GRF during operationally relevant tasks.

Purpose
Develop a statistically based model to predict pGRFvert during loaded walking from ActiGraph GT3X+ activity monitor (AM) vertical acceleration.

Methods
Fifteen male Soldiers (25.4 ± 5.3 yr, 85.8 ± 9.2 kg, 1.79 ± 9.3 m) wore an ActiGraph GT3X+ AM over their right hip. Six walking trials (0.67–1.58 m·s−1) with four loads (no load, 15, 27, 46 kg) and two types of footwear (athletic shoes and combat boots) were completed on an instrumented force plate treadmill. Average peak vertical AM acceleration (pACCvert) and pGRFvert were used to develop a regression equation to predict pGRFvert. The model was validated using a leave-one-subject-out approach. Root mean square error (RMSE) and average absolute percent difference (AAPD) between actual and predicted pGRFvert were determined. pGRFvert was also predicted for two novel data sets and AAPD and RMSE calculated.

Results
The final equation to predict pGRFvert included pACCvert, body mass, carried load mass, and pACCvert-carried load mass interaction. Cross-validation resulted in an AAPD of 4.0% ± 2.7% and an RMSE of 69.5 N for leave-one-subject-out and an AAPD of 5.5% ± 3.9% and an RMSE of 78.7 N for the two novel data sets.

Conclusion
A statistically based equation developed to predict pGRFvert from ActiGraph GT3X+ AM acceleration proved to be accurate to within 4% for Soldiers carrying loads while walking. This equation provides a means to predict GRF without a force plate.
The Yips: Methods to Identify Golfers with a Dystonic Etiology/Golfer’s Cramp
Authors: ADLER CHARLES H. , TEMKIT M’HAMED , CREWS DEBRA , MCDANIEL TROY , TUCKER JENNIFER , HENTZ JOSEPH G. , MARQUARDT CHRISTIAN , ABRAHAM DALE , CAVINESS JOHN N. 
Published: June 2018

ABSTRACT

Purpose
To determine whether quantitative methods could separate golfers with a possible dystonic cause of the “yips” from those that appear to be nondystonic.

Methods
Twenty-seven golfers completed 10 two-handed and 10 right hand–only putts. Surface EMG assessed forearm muscle co-contraction and motion detectors monitored wrist and putter movements. Based on a videotape review, golfers were grouped into those with yips of dystonic etiology, those with the yips nondystonic, and those with no yips.

Results
On video review of two-handed putting, five golfers had yips that appeared to be dystonic, nine had yips that did not appear to be dystonic, and 13 had no yips. During two-handed putting co-occurrence of a yipped putt and wrist flexor/extensor and/or pronator/supinator co-contraction was significantly more frequent in those with dystonic yips. The dystonic group had no increase in the number of yipped putts or yips with co-contraction when putting right hand only, whereas the nondystonic group had significantly more yipped putts and more yipped putts with co-contraction with right hand only.

Conclusions
Quantitative methods were identified that appear to identify golfers with a dystonic etiology for the yips. It is not just the frequency of yips nor just specific motion patterns alone, rather it is also a combination of yips with co-occurring co-contraction when putting with two hands, and then right hand only, that distinguished this possible etiology. Despite being a small study, identifying a dystonic pattern, even in a nonpressure indoor setting, may aid in assessment and possible monitoring of treatment.
The ICR639 CPG NGS validation series: A resource to assess analytical sensitivity of cancer predisposition gene testing
Authors: Mahamdallie Shazia , Ruark Elise , Holt Esty , Poyastro-Pearson Emma , Renwick Anthony , Strydom Ann , Seal Sheila , Rahman Nazneen 
Published: June 2018

The analytical sensitivity of a next generation sequencing (NGS) test reflects the ability of the test to detect real sequence variation. The evaluation of analytical sensitivity relies on the availability of gold-standard, validated, benchmarking datasets. For NGS analysis the availability of suitable datasets has been limited. Most laboratories undertake small scale evaluations using in-house data, and/or rely on in silico generated datasets to evaluate the performance of NGS variant detection pipelines. Cancer predisposition genes (CPGs), such as BRCA1 and BRCA2, are amongst the most widely tested genes in clinical practice today. Hundreds of providers across the world are now offering CPG testing using NGS methods. Validating and comparing the analytical sensitivity of CPG tests has proved difficult, due to the absence of comprehensive, orthogonally validated, benchmarking datasets of CPG pathogenic variants. To address this we present the ICR639 CPG NGS validation series. This dataset comprises data from 639 individuals. Each individual has sequencing data generated using the TruSight Cancer Panel (TSCP), a targeted NGS assay for the analysis of CPGs, together with orthogonally generated data showing the presence of at least one CPG pathogenic variant per individual. The set consists of 645 pathogenic variants in total. There is strong representation of the most challenging types of variants to detect, with 339 indels, including 16 complex indels and 24 with length greater than five base pairs and 74 exon copy number variations (CNVs) including 23 single exon CNVs. The series includes pathogenic variants in 31 CPGs, including 502 pathogenic variants in BRCA1 or BRCA2, making this an important comprehensive validation dataset for providers of BRCA1 and BRCA2 NGS testing. We have deposited the TSCP FASTQ files of the ICR639 series in the European Genome-phenome Archive (EGA) under accession number EGAD00001004134.