bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prospective teachers’ metacognitive awareness levels of reading strategies
Authors: Aşıkcan Mehmet , Saban Ahmet 
Published: April 2018

The main purpose of this study is to determine prospective teachers’ metacognitive awareness levels of reading strategies. A quantitative surve method was used. Participants consisted of 150 prospective primary teachers and 150 prospective Turkish language teachers from Necmettin Erbakan University in Turkey. The data were collected through Metacognitive Awareness of Reading Strategies Inventory during the spring semester of the 2014–2015 academic year. Results show that prospective teachers’ global reading and problem solving strategies levels are high while their support reading strategies level is medium. Female participants’ metacognitive awareness level was found to be higher compared to males. Prospective Turkish language teachers’ problem solving strategies level is higher than that of prospective primary teachers. Prospective primary teachers preferred historical and psychological books more while prospective Turkish Language teachers favoured all types of books equally. The metacognitive awareness levels of participants reading book everyday and sometimes are significantly higher than those of reading book never.

Keywords: Metacognitive awareness, reading strategies, prospective teachers.
Application examples and student views on active learning approach integrated with branches of art
Authors: Orak Seval , Demirci Cavide 
Published: April 2018

This study aims to analyse the views of elementary school students on active learning integrated with art branches in core courses (Turkish, mathematics, science and social studies). The research was conducted in the province of Bursa during the academic year 2015–2016, and the study sample comprised of 22 students, including 15 male and 7 female students. The core courses of elementary school were taught using active learning techniques, and the subjects taught during the lessons were evaluated through art branches. The research data obtained through observation and by means of an interview form were analysed and interpreted by descriptive analysis method. The frequencies and percentages of the data obtained using qualitative analysis were calculated. Through active learning approaches, the students learnt better and in a more enjoyable way, their self-esteem also increased. Thus, the elementary school students had positive views on active learning integrated with art branches in core courses.

Keywords: Active learning approach, arts branches, student views, interdisciplinary teaching.
Climate change impacts on water balance in Western Bohemia and options for adaptation
Authors: Beran Adam , Hanel Martin , Nesládková Magdalena , Vizina Adam , Vyskoč Petr , Kožín Roman 
Published: April 2018

Abstract
Several basins in Western Bohemia are regularly confronted with water scarcity problems during dry periods that have far-reaching impacts on stream ecology and the availability of drinking water for users. This paper presents a hydrological balance assessment of catchments in Western Bohemia for present and future conditions together with possible directions for climate change adaptation at the local scale. Assessment of climate change impacts on hydrological balance components using an ensemble of regional climate models revealed an increase in air temperature for all months during the year leading to an increase in evaporation. Along with changes in precipitation distribution during the year (increasing winter precipitation and decreasing summer precipitation), groundwater recharge and groundwater storage in general both decrease. Adaptation measures such as water transfers and the construction of water reservoirs are assessed with respect to the goal of increasing water availability in the Western Bohemia region during dry periods.
Utilização de geotecnologias para anílise de uso da terra no PA Matupi, Amazonas
Authors: CORREIA Rodrigo Nascimento , LEAL Matheus Lucas Maciel , DA SILVA Viviane Vidal , DA SILVA Tatiana Acácio , FERNANDES Wanessa Monteiro 
Published: April 2018

Os assentamentos rurais estão entre as principais variáveis relacionadas a devastação da Amazônia Legal, principalmente em função da prática da atividade pecuária. Esse cenário tem sido estudado por diferentes áreas como biologia, ciências sociais e geociências. Este artigo objetiva analisar e quantificar o uso e ocupação da terra no Projeto de Assentamento Matupi, localizado na mesorregião do Sul Amazonense, no município de Manicoré/AM. Foram delimitadas como classes de uso da terra para este estudo: Floresta, Pastagem abandonada e Pastagem. Utilizou-se uma cena do satélite Landsat-8 sensor OLI, e com o auxílio do software de Sistema de Informações Geográficas (SIG), QGIS 2.8.1, obteve-se a classificação digital da cena da área em estudo, gerando como produto um mapa temático. Verifica-se que 42,35% da área total do assentamento é composta por Floresta, 23,43% de Pastagem abandonada e 34,22% de Pastagem. Desta forma, pode-se concluir que esta localidade apresenta alto índice de desmatamento, o qual se deve a predominância das classes de Pastagem, que totalizam 57,65% da área total do assentamento.
Pharmacoepigenetics and Pharmacoepigenomics: An Overview
Authors: Peedicayil Jacob 
Published: April 2018

Background:
The rapid and major advances being made in epigenetics are impacting
pharmacology, giving rise to new sub-disciplines in pharmacology, pharmacoepigenetics, the study of
the epigenetic basis of variation in response to drugs; and pharmacoepigenomics, the application of
pharmacoepigenetics on a genome-wide scale.

Methods:
This article highlights the following aspects of pharmacoepigenetics and pharmacoepigenomics:
epigenetic therapy, the role of epigenetics in pharmacokinetics, the relevance of epigenetics to adverse drug
reactions, personalized medicine, drug addiction, and drug resistance, and the use of epigenetic biomarkers
in drug therapy.

Results:
Epigenetics is having an increasing impact on several areas of pharmacology.

Conclusion:
Pharmacoepigenetics and pharmacoepigenomics are new sub-disciplines in pharmacology
and are likely to have an increasing impact on the use of drugs in clinical practice.
Genoprotective Effect of New Triazine Derivatives in Endosulfan Mediated Toxicity, an In vivo and In vitro Study
Authors: Naderi Nima , Najarkolaee Seyed Mostafa Ghasemi , Modanlookordi Mona , Shokrzadeh Mohammad , Irannejad Hamid 
Published: April 2018

Background:
Recently, we reported synthesis and neuroprotective activity of some new
1,2,4-triazine derivatives against H2O2 and &#946;-amyloid toxicity in two neurotic cell lines, SHSY5Y
and PC12.

Methods:
The promising results obtained prompted us to further study on these potent neuroprotective
agents. In the current study, in vivo anti-inflammatory effect and also genoprotective activity of
these compounds in endosulfan-mediated toxicity were investigated. Compounds RT and SMO
exhibited high anti-inflammatory effect at 3 and 4 hours after injection in 20 mg/kg, and were even
more effective than Indomethacin (20 mg/kg).

Results:
Interestingly, compound SMO in 200 &#181;M was the best compound in reducing micronuclei
significantly (P value <0.0001) in lymphocytes treated with endosulfan compared to control group.

Conclusion:
Herein, we report SMO as a genoprotective agent and a new drug candidate for endosulfan
mediated toxicity.
Stereocomplexation Assisted Assembly of Poly(γ-glutamic Acid)-graft-polylactide Nano-micelles and Their Efficacy as Anticancer Drug Carrier
Authors: Dai Shulin , Feng Yucheng , Li Shuyi , Chen Yuxiao , Liu Meiqing , Zhang Chao , Zhang Wei , Yin Yihua 
Published: April 2018

Background:
Micelles as drug carriers are characterized by their inherent instability due to the weak
physical interactions that facilitate the self-assembly of amphiphilic block copolymers. As one of the strong
physical interactions, the stereocomplexation between the equal molar of enantiomeric polylactides, i.e., the
poly(L-lactide) (PLLA) and poly(D-lactide) (PDLA), may be harnessed to obtain micelles with enhanced stability
and drug loading capacity and consequent sustained release.
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Aims/Methods: In this paper, stereocomplexed micelles gama-PGA-g-PLA micelles) were fabricated from the
stereocomplexation between poly(gama-glutamic acid)-graft-PLLA gama-PGA-g-PLA) and poly(gamaglutamic
acid)-graft-PDLA gama-PGA-g-PLA). These stereocomplexed micelles exhibited a lower CMC than
the corresponding enantiomeric micelles.

Result:
Furthermore, they showed higher drug loading content and drug loading efficiency in addition to more
sustained drug release profile in vitro. In vivo imaging confirmed that the DiR-encapsulated stereocomplexed
gama-PGA-g-PLA micelles can deliver anti-cancer drug to tumors with enhanced tissue penetration. Overall,
gama-PGA-g-PLA micelles exhibited greater anti-cancer effects as compared with the free drug and the stereocomplexation
may be a promising strategy for fabrication of anti-cancer drug carriers with significantly enhanced
efficacy.
VDAC1 Mediated Anticancer Activity of Gallic Acid in Human Lung Adenocarcinoma A549 Cells
Authors: Maimaiti Aikebaier , Aili Amier , Kuerban Hureshitanmu , Li Xuejun 
Published: April 2018

Aims: Gallic acid (GA) is generally distributed in a variety of plants and foods, and possesses
cell growth-inhibiting activities in cancer cell lines. In the present study, the impact of GA on cell viability,
apoptosis induction and possible molecular mechanisms in cultured A549 lung carcinoma cells was investigated.

Methods:
In vitro experiments showed that treating A549 cells with various concentrations of GA inhibited cell
viability and induced apoptosis in a dose-dependent manner. In order to understand the mechanism by which
GA inhibits cell viability, comparative proteomic analysis was applied. The changed proteins were identified by
Western blot and siRNA methods.

Results:
Two-dimensional electrophoresis revealed changes that occurred to the cells when treated with or
without GA. Four up-regulated protein spots were clearly identified as malate dehydrogenase (MDH), voltagedependent,
anion-selective channel protein 1(VDAC1), calreticulin (CRT) and brain acid soluble protein
1(BASP1). VDAC1 in A549 cells was reconfirmed by western blot. Transfection with VDAC1 siRNA significantly
increased cell viability after the treatment of GA. Further investigation showed that GA down regulated
PI3K/Akt signaling pathways. These data strongly suggest that up-regulation of VDAC1 by GA may play an
important role in GA-induced, inhibitory effects on A549 cell viability.
Structure and Performance Evaluation of Fractional Lower-Order Covariance Method in Alpha-Stable Noise Environments
Authors: Ahmed Areeb , Savaci Ferit Acar 
Published: April 2018

Background:
All existing time delay estimation methods, i.e. correlation and covariance,
depend on second or higher-order statistics which are inapplicable for the correlation of alpha-stable
noise signals. Therefore, fractional lower order covariance is the most appropriate method to measure
the similarity between the alpha-stable noise signals.

Methods:
In this paper, the effects of skewness and impulsiveness parameters of alpha-stable distributed
noise on fractional lower order covariance method have been analyzed.

Results:
It has been found that auto-correlation, i.e. auto fractional lower order covariance,\ of non
delayed alpha-stable noise signals follows a specific trend for specific ranges of impulsiveness and
skewness parameters of alpha-stable distributed noise. The results also depict that, by maintaining the
skewness and impulsiveness parameters of α-stable noise signals in a certain suggested range, better
auto-correlation can be obtained between the transmitted and the received alpha-stable noise signals in
the absence and presence of additive white Gaussian noise.

Conclusion:
The obtained results would improve signal processing in alpha-stable noise environment
which is used extensively to model impulsive noise in many noise-based systems. Mainly, it would
optimize the performance of random noise-based covert communication, i.e. random communication.
Substance Use Disorder Related to Kratom (Mitragyna speciosa) Use in Malaysia
Authors: Singh Darshan , Abdullah Mohammad F.I.L. , Vicknasingam Balasingam K. , Müller Christian P. 
Published: April 2018

Background:
Kratom is a traditional medicinal herb with mild addictive properties.
Nevertheless, current available data on substance use disorder related to kratom use is
scarce. This study aims to clinically evaluate and identify factors that are associated with
kratom use disorder among regular kratom tea/juice users in traditional settings in Malaysia.
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Method: 150 regular kratom users were recruited through convenient sampling for this crosssectional
study. They were interviewed with Mini International Neuropsychiatric Interview
(M.I.N.I.) to diagnose substance use disorder related to kratom use, while the Ketum Dependence
Scale (KDS) and Clinical Opioid Withdrawal Scale (COWS) were administered to
evaluate kratom dependence and withdrawal severity.

Results:
All subjects were males with the majority being Malays (99%, n=148/150). More
than half were single (n=84/150), had secondary education (91%, n=136/150), and were employed
(93%, n=139/150). Almost all (99%) fulfilled the criteria for substance use disorder
related to kratom use, 95% reported withdrawal symptoms on abstinence, 87% reported
tolerance, and 93% craving for kratom. Results from Chi-square analysis indicated that higher
quantity (>3 glasses) of daily kratom tea/juice consumption was significantly associated
with severe kratom dependence (OR: 2.1: 1.0-4.5: p<.041) and moderate withdrawal (OR:
3.1: 1.5-6.3: p<.002). Similarly, those who consumed >3 glasses of brewed kratom tea daily
had higher odds of reporting longer kratom use history (>7 years) (OR: 4.4: 2.2-8.8: p<.001)
and higher frequency of daily kratom use (>5 times) (p<.001), compared to those who consumed
less than three glasses of kratom daily.

Conclusion:
Our findings indicated that regular and chronic (>3 glasses daily) kratom
tea/juice consumption was associated with kratom use disorder, severe kratom dependence
and moderate withdrawal.
Healthcare Utilization after Acute Kidney Injury in the Pediatric Intensive Care Unit
Authors: Hessey Erin , Morissette Geneviève , Lacroix Jacques , Perreault Sylvie , Samuel Susan , Dorais Marc , Phan Véronique , Jouvet Philippe , Lafrance Jean-Philippe , LeLorier Jacques , Palijan Ana , Pizzi Michael , Roy Louise , Zappitelli Michael 
Published: April 2018

Background and objectives
Little is known about the long-term burden of AKI in the pediatric intensive care unit. We aim to evaluate if pediatric AKI is associated with higher health service use post–hospital discharge.

Design, setting, participants, & measurements
This is a retrospective cohort study of children (≤18 years old) admitted to two tertiary centers in Montreal, Canada. Only the first admission per patient was included. AKI was defined in two ways: serum creatinine alone or serum creatinine and/or urine output. The outcomes were 30-day, 1-year, and 5-year hospitalizations, emergency room visits, and physician visits per person-time using provincial administrative data. Univariable and multivariable Poisson regression were used to evaluate AKI associations with outcomes.

Results
A total of 2041 children were included (56% male, mean admission age 6.5±5.8 years); 299 of 1575 (19%) developed AKI defined using serum creatinine alone, and when urine output was included in the AKI definition 355 of 1622 (22%) children developed AKI. AKI defined using serum creatinine alone and AKI defined using serum creatinine and urine output were both associated with higher 1- and 5-year hospitalization risk (AKI by serum creatinine alone adjusted relative risk, 1.42; 95% confidence interval, 1.12 to 1.82; and 1.80; 1.54 to 2.11, respectively [similar when urine output was included]) and higher 5-year physician visits (adjusted relative risk, 1.26; 95% confidence interval, 1.14 to 1.39). AKI was not associated with emergency room use after adjustments.

Conclusions
AKI is independently associated with higher hospitalizations and physician visits postdischarge.
Flared Roots Reinforced With Bulk-fill Flowable Composite — Case Report
Authors: Braz R , Mergulhão VA , Oliveira LR , Alves MS , Canto CA 
Published: April 2018

SUMMARY
This article presents a case report for the treatment of a patient with a flared root. The patient was treated with a bulk-fill flowable composite. This innovative approach seems to be efficient in reinforcing flared roots. The advantages and disadvantages of the technique are presented.
Compliance of Randomized Clinical Trials in Noncarious Cervical Lesions With the CONSORT Statement: A Systematic Review of Methodology
Authors: Reis A , de Geus JL , Wambier L , Schroeder M , Loguercio AD 
Published: April 2018

SUMMARY
The literature was reviewed to evaluate the compliance of randomized clinical trials (RCTs) with the CONsolidated Standards of Reporting Trials (CONSORT ) and the risk of bias of these studies through the Cochrane Collaboration risk of bias tool (CCRT). RCTs were searched at Cochrane Library, PubMed, and other electronic databases to find studies about adhesive systems for cervical lesions. The compliance of the articles with CONSORT was evaluated using the following scale: 0 = no description, 1 = poor description, and 2 = adequate description. Descriptive analyses about the number of studies by journal, follow-up period, country, and quality assessments were performed with CCRT for assessing risk of bias in RCTs. One hundred thirty-eight RCTs were left for assessment. More than 30% of the studies received scores of 0 or 1. Flow chart, effect size, allocation concealment, and sample size were more critical items, with 80% receiving a score of 0. The overall CONSORT score for the included studies was 15.0 ± 4.8 points, which represents 46.9% of the maximum CONSORT score. A significant difference among countries was observed (p&lt;0.001), as well as range of year (p&lt;0.001). Only 4.3% of the studies were judged as at low risk; 36.2% were classified as having unclear risk and 59.4% as having high risk of bias. The adherence of RCTs evaluating adhesive systems to the CONSORT is low with unclear/high risk of bias.
Mapeamento do processo de alta para pacientes de ambulatório cirúrgico baseado em contrarreferência de um hospital público de ensino de alta complexidade do município do São Paulo
Authors: Nascimento Jaqueline Oliveira Valdevino , Becker Ana Cláudia , Eiroz Rosangela , Camargo Paula Cristina Souto de 
Published: April 2018

Introdução: Na gestão hospitalar, sistemas de referência e contrarreferência efetivos atuam como elementos essenciais para a integração das redes de saúde diante da complexidade dos serviços. Objetivo: Mapear o processo de alta de um hospital público de ensino de alta complexidade do município do São Paulo e criar protocolos de contrarreferência para pacientes atendidos nos Ambulatórios do Serviço de Cirurgia do Esôfago e Fígado e Hipertensão Portal. Método: Estudo descritivo, com revisão bibliográfica e realização de Benchmarking, sendo desenvolvida uma proposta de melhoria para a área interessada. Resultado: Foi realizado um diagnóstico situacional do setor ambulatorial onde se notou uma falta de padronização em relação ao documento utilizado e elaborados relatórios de alta e protocolos para diagnósticos específicos de acordo com os protocolos terapêuticos dos grupos analisados. Conclusão: Faz-se necessário a criação de protocolos de contrarreferência a fim de diminuir a demanda e a superlotação dos hospitais de alta complexidade com casos que poderiam ser sanados na rede de saúde com atenção menos especializada, otimizando assim o sistema de saúde e respeitando seu caráter hierarquizado e de rede.Palavras-chave: Administração de Serviços de Saúde; Assistência Ambulatorial; Administração Hospitalar; Gestão em Saúde; Hospitais Públicos; Hospitais de Ensino. Abstract:Introduction: In hospital management, effective referral and counter-referral systems act as essential elements for the health networks integration in the face of service complexity. Objective: To map the discharge process of a high complexity public teaching hospital in the city of São Paulo and create counter-referral protocols for patients attending the Ambulatory Esophageal and Liver Surgery and Portal Hypertension Clinical Services. Method: A descriptive study, with a bibliographic review and Benchmarking, and an improvement proposal were developed for the area. Outcome: A situational diagnosis was performed in the outpatient clinic where a lack of document standardization was observed, then discharge reports and protocols for specific diagnoses were elaborated according to the therapeutic protocols of the analyzed groups. Conclusion: It is necessary to create counter-referral protocols in order to reduce the demand and overcrowding of highly complex hospitals with cases that could be treated in the health network with less specialized health services, thus optimizing the health system and respecting its hierarchical and network character. Keywords: Health Services Administration; Ambulatory Care; Hospital Administration; Hospital Administration; Health Management; Hospitals, Public; Hospitals, Teaching.
IMPLEMENTASI ASESMEN DIAGNOSTIK DALAM UPAYA MENINGKATKAN HASIL BELAJAR MATEMATIKA DI SD KOTA BANJARBARU KALIMANTAN SELATAN
Authors: Darmiyati Darmiyati 
Published: April 2018

Penelitian ini bertujuan untuk memverifikasi apakahÂ pelaksanaan asesmen diagnostik melalui penilaian tes, non tes, dan remedial dapat meningkatkan hasil belajar matematika di SekolahÂ Dasra (SD). Penelitian ini dilaksanakan di kelas 3 SDN 04 Banjarbaru Utara 4, dengan jumlah sampel 34 orang siswa. Jenis penelitian yangÂ digunakan adalah penelitian tindakan kelas. Penelitian ini dibantuÂ oleh tiga orang kolaborator yang mengikuti langkah-Iangkah praÂ observasi, perencanaan tindakan, pelaksanaan tindakan dan rejleksi.Â Penelitian ini dilaksanakan empat siklus, subjek penelitian ini guruÂ dan siswa, data dikumpulkan melalui tes, kuesioner sikap, observasiÂ perilaku siswa, dan wawancara. Analisis data yang digunakan dalamÂ penelitian ini adalah kualitatif dan kuantitatif Hasil penelitianÂ menunjukkan bahwa hasil belajar siswa meningkat setelah setiap topikÂ pembelajaran diberikan asesmen diagnostik, berupa pemberian tes,Â remedial, dan non tes berupa kuesioner sikap siswa, observasi perilakuÂ siswa mengikuti pembelajaran matematika.
PROFESI GURU SEBAGAI PROFESI YANG MENJANJIKAN PASCA UNDANG-UNDANG GURU DAN DOSEN
Authors: Subijanto Subijanto 
Published: April 2018

Undang-Undang Nomor 14/2005 tentang Guru dan Dosen pada hakikatnya untuk mengangkat harkat dan martabat guru sebagai pendidik profesional. Sebagai guru profesional guru wajib: (a) memiliki kualifikasi akademik minimal sarjana/diploma empat; (b) memiliki kompetensi (pedagogik, kepribadian, sosial, dan profesional; (c) memiliki sertifikat pendidik, (d) sehat jasmani dan rokhani, dan (e) memiliki kemampuan untuk mewujudkan tujuan pendidikan nasional. Dalam melaksanakan tugas keprofesionalannya guru memperoleh penghasilan di atas kebutuhan hidup minimal danÂ jaminan kesejahteraan sosial, yang meliputi: (1) gaji pokok, (2) tunjangan yang melekat pada gaji, serta (3) penghasilan lain berupa tunjangan profesi, tunjangan fungsional, tunjangan khusus, dan maslahat tambahan yang terkait dengan tugasnya dengan prinsip penghargaan atas dasar prestasai. Ke depan, profesi guru cukupÂ menjanjikan dan diharapkan menjadi pilihan pertama bagi generasi muda atau setidak-tidaknya menjadi pilihan yang sama dengan profesi lainnya, seperti dokter; akuntan, insinyur, advokat, notaris tdan lainÂ­ lainnya.