bluuebunny/crossref_metadata_2025_split huggingface dataset:
Addition of one session with a specialist counselor did not increase efficacy of a family physician-led smoking cessation program
Authors: Chung Yi-Hsuan , Chang Hao-Hsiang , Lu Chia-Wen , Huang Kuo-Chin , Guo Fei-Ran 
Published: June 2018

Objective Higher-intensity counseling sessions increase the smoking abstinence rate. However, counselors are limited in Taiwan. This study was performed to determine whether the addition of one session with a specialist counselor increases the efficacy of a family physician-led smoking cessation program. Methods Participants opted to either visit a family physician for brief counseling and pharmacotherapy (Po) or visit a specialist counselor for an initial session followed by a family physician for brief counseling sessions with pharmacotherapy (P+). The 7-day point prevalence (PP) rate was evaluated at weeks 12 and 24. Results In total, 356 patients were enrolled. In the intention-to-treat analysis, the PP rate at week 12 was higher in the Po than P+ group, but there was no significant difference at week 24. In the per-protocol analysis, the PP rates at weeks 12 and 24 were not significantly different between the Po and P+ groups. The adjusted odds ratios also revealed no significant differences in either the intention-to-treat analysis or the per-protocol analysis between the two groups. Conclusion The addition of one session with a specialist counselor had no benefit over the provision of counseling through a family physician at either 12 or 24 weeks of follow-up.
Estimating Event Likelihood for Rock Slope Assets on Transportation Networks
Authors: Mines Aine , Beckstrand Darren , Thompson Paul D. , Boundy Bret , Helm Scott , Jackson Jeff 
Published: June 2018

Recent federal regulations require states to develop risk-based transportation asset management (TAM) plans for bridge and pavement assets. These requirements are making TAM principles, and their related benefits and tools, familiar to a variety of sections within Departments of Transportation (DOTs) and prompting select DOTs to apply them to select geotechnical assets. The Montana Department of Transportation (MDT) recently completed a multi-year project to update its previous Rockfall Hazard Rating System (RHRS) into a Rock slope Asset Management Program (RAMP), incorporating some of these new tools. Incorporating risk into decision-making is important, but risk posed by deteriorating geotechnical assets is difficult for departments to quantify. Adverse event data are often collected in an ad-hoc fashion, with only the worst events attracting attention. As part of the RAMP project, an MDT-administered adverse event survey was combined with a statewide dataset of detailed rock slope assessments. These data were used to develop initial relationships between rock slope condition and adverse event likelihood per unit area of rock slope face. Annual likelihood of both service disrupting events and accidents was calculated for each rock slope in MDT’s database and used to identify high-risk corridors. Using established AASHTO methods, event likelihood was combined with traffic and detour data, generating site-specific estimates of annual safety and mobility risks, expressed in dollars, which can be incorporated into benefit/cost tools at various planning levels and permits dollar-to-dollar comparisons of the risks posed by rock slope assets to other actively managed assets.
Ethical challenges experienced by public health nurses related to adolescents’ use of visual technologies
Authors: Laholt Hilde , McLeod Kim , Guillemin Marilys , Beddari Ellinor , Lorem Geir 
Published: June 2018

Background: Visual technologies are central to youth culture and are often the preferred communication means of adolescents. Although these tools can be beneficial in fostering relations, adolescents’ use of visual technologies and social media also raises ethical concerns. Aims: We explored how school public health nurses identify and resolve the ethical challenges involved in the use of visual technologies in health dialogues with adolescents. Research design: This is a qualitative study utilizing data from focus group discussions. Participants and research context: We conducted focus group discussions using two semi-structured discussion guides with seven groups of public health nurses (n = 40) working in Norwegian school health services. The data were collected during January and October 2016. Discussions were audio recorded, transcribed, and coded into themes and subthemes using systematic text condensation. Ethical considerations: The leader of the public health nursing service who agreed to provide access for the study and the Norwegian Center for Research Data that reviewed and approved the study. All participants gave informed consent. Findings: In adolescents’ use of visual materials with public health nurses, ethical concerns were raised regarding suicide ideations, socially unacceptable content, violation of privacy, and presentations of possible child neglect. The nurses utilized their professional knowledge and experience when identifying and navigating these ethical dilemmas; they resolved ethical uncertainties through peer discussion and collaboration with fellow nurses and other professionals. Discussion: We discussed the findings in light of Annemarie Mol’s interpretation of the ethics of care. Mol expands the notion of ethical care to include the action of technologies. Conclusion: Although the increasing use of visual technologies offered benefits, school nurses faced ethical challenges in health dialogues with adolescents. To address and navigate these ethical issues, they relied on their experience and caring practices based on their professional ethics. Uncertainties were resolved through peer dialogue and guidance.
The Extent to Which Professional Advice Can Reduce the Disposition Effect: An Emerging Market Study
Authors: Bashall James , Willows Gizelle D. , West Darron 
Published: June 2018

This study tests for the disposition effect in South Africa across two classes of non-professional investors: those acting in their own capacity and those acting with the assistance of professional investment advisors. The trade history of 4,840 investor accounts from a South African stockbroker was analysed over the 5-year period from October 2008 to October 2013. The results showed that individual investors in South Africa exhibit the disposition effect. However, investors acting with the assistance of professional advisors show the effect to a lesser extent which was found to be rationally justifiable on the grounds of portfolio rebalancing. JEL Classification: G11, G14, G40, G41
Comparing Australian garment and childcare homeworkers’ experience of regulation and representation
Authors: Delaney Annie , Ng Yee-Fui , Venugopal Vidhula 
Published: June 2018

AbstractLabour markets in Australia have long been segmented by gender and race. This study compares two highly gendered and racially segmented labour markets, home-based family day care workers and garment homeworkers. The comparative cases examine the broader trends of migration, production and consumption that reinforce gender and racial stereotypes, and discourses that underpin representations that women workers are ideally suited to such work. We theorise the gender and racialised inequalities of homework based on the literature on invisibilisation and social reproduction to explore the vulnerable position of migrant women and the consequences of having limited options, such as legal and social protections and any capacity to collectively organise. Our analysis examines the roles and responses of institutions and conceptualises the socio-political factors that affect the characterisation of homework as non-work or as self-employed entrepreneurial activities. By mapping the differing regulatory trajectories of these two groups of homeworkers in terms of regulation and representation, we find both similarities and differences. While garment homeworkers have achieved recognition through legislation and social mobilisation, their circumstances leave them less likely to access such rights. By contrast, the failure to recognise family day care homeworkers, has left them to market forces.
Body composition of lean outdoor intact cats vs lean indoor neutered cats using dual-energy x-ray absorptiometry
Authors: Cline Martha G , Witzel Angela L , Moyers Tamberlyn D , Kirk Claudia A 
Published: June 2018

Objectives The objectives for this study were to compare the body composition of adult indoor neutered domestic cats with outdoor intact cats with an ideal body condition score using dual-energy x-ray absorptiometry, and to report the body composition findings of free-roaming cats, as this has not been previously reported. Most domestic house cats differ from free-roaming cats as they are confined indoors and neutered. Indoor neutered cats have reduced activity and hormonal alterations that may result in lower muscle mass and higher body fat percentages vs outdoor intact cats, despite similar body condition scores. Methods Twenty-one outdoor intact cats (10 male, 11 female) were selected from a trap–neuter–return program and 16 indoor neutered domestic cats (10 male, six female) were client-owned. Inclusion criteria included an estimated age between 1 and 6 years, complete blood count, biochemistry panel, urinalysis, total thyroxine, feline leukemia virus/feline immunodeficiency virus screening and a body condition score of 4–5/9. Results Indoor neutered cats had a higher body fat percentage (22.1% [range 17.3–28.2%]) than outdoor intact cats (17.3% [range 10.0–33.6%]; P = 0.002). Indoor neutered male cats had a higher body fat percentage ( P <0.001) than outdoor intact cats. No difference in body fat percentage was observed in female cats ( P = 0.159). Indoor neutered domestic cats had a higher bone mineral density than outdoor intact cats ( P = 0.023). Conclusions and relevance The results of this study suggest indoor confinement and neutering increase body fat percentage and bone mineral density in cats with an ideal body condition score.
High Frequency of Extractable Nuclear Autoantibodies in Wheat-Related Disorders
Authors: Yang Yuanyuan , Krishna Karthik , Deshpande Payal , Ranganathan Vinodh , Jayaraman Vasanth , Wang Tianhao , Bei Kang , Krishnamurthy Hari 
Published: June 2018

Background and aims: There has been broad interest to explore the presence of autoimmunity among wheat-sensitive individuals, but neither the pathogenesis nor the relevance has been established. In this study, we evaluated the frequencies and levels of autoantibodies, which are important biomarkers of autoimmunity, in subjects with wheat-related disorders and controls. Anti-nuclear antibodies (ANA) and the specific ones against extractable nuclear antigens (ENA) were investigated. Methods: A total of 713 subjects who showed symptoms related to wheat ingestion were addressed to Vibrant America Clinical Laboratory from December 2015 to November 2017. Serum samples were collected from all subjects and tested with a wheat protein antibody panel (IgG and IgA to 18 proteins at the peptide level) and an autoantibody panel (ANA by immunofluorescence analysis and 10 ENA antibodies). Retrospective analysis was completed using de-identified clinical data and test results. Results: In the retrospective analysis, 38 (5%) were seropositive in a Celiac Disease panel, 491 (83%) were seropositive in a wheat protein antibody panel “Wheat Zoomer,” and 84 (12%) were seronegative in both panels. Anti-nuclear antibodies were detected in similar portions of the celiac disease subjects (13%), the Wheat Zoomer–positive subjects (12%), and seronegative controls (15%), which is also very close to the reported occurrence of ANA positivity (15%) in the healthy population. The prevalence of anti-ENA was reported to be less than 2% in the general population; however, our study found it to be much higher in the celiac disease subjects (29%) and the wheat-sensitive subjects (27%), compared with a smaller proportion of seronegative controls (19%). The prevalence of anti-histone was especially prominent among the celiac disease subjects (73%) and the Wheat Zoomer–positive subjects (60%). Conclusions: High proportions of wheat-related disease subjects carry ENA antibodies that are important specific biomarkers of autoimmunity.
EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country
Authors: Mooney Thomas , Smout Elizabeth , Leigh Bailah , Greenwood Brian , Enria Luisa , Ishola David , Manno Daniela , Samai Mohamed , Douoguih Macaya , Watson-Jones Deborah 
Published: June 2018

Background/aims During the 2014–2016 West African Ebola epidemic, clinical trials were fast-tracked in order to identify prophylactic vaccines and experimental treatments that might be useful in preventing or treating Ebola. These trials included the ongoing EBOVAC-Salone study, which was established and implemented in Sierra Leone to assess the safety and immunogenicity of the Ad26.ZEBOV/MVA-BN-Filo prime-boost Ebola vaccine regimen. Methods This article describes the experiences of the EBOVAC-Salone research team in setting up and implementing the trial, and provides recommendations for research teams aiming to conduct clinical trials in future outbreak situations. Results Establishing a clinical trial during an outbreak brought some unique challenges, including those related to trial design and the regulatory environment, operational issues, and community engagement. The situation was further complicated by the weak infrastructure and limited experience of clinical trials in Sierra Leone. However, operating in an outbreak context also brought some benefits to the research team, including strong stakeholder support. The EBOVAC-Salone study recruited participants both during and after the outbreak, leading to additional challenges to trial implementation during the post-outbreak transition. Conclusion Many lessons have been learned about setting up and implementing a clinical trial during a devastating Ebola epidemic, and some of the experiences of the EBOVAC-Salone team were mirrored by those of other researchers operating in the region. Common to several of these research groups is a recommendation that research should be more closely incorporated into outbreak response planning, which could expedite the establishment of timely and appropriate research projects. We recommend that the lessons learned by researchers during the West African Ebola epidemic are built into programmes and strategies to improve the responses to future epidemics, wherever they occur.
Risk factors for and timing of adverse events after revision total shoulder arthroplasty
Authors: Keswani Aakash , Chi Debbie , Lovy Andrew J , London Daniel A , Cagle Paul J , Parsons Bradford O , Bosco Joseph A 
Published: June 2018

Background Despite increasing rates of revision total shoulder arthroplasty (RTSA), there is a paucity of literature on optimizing perioperative outcomes. The purposes of this study were to identify risk factors for unplanned readmission and perioperative complications following RTSA, risk-stratify patients based on these risk factors, and assess timing of complications. Methods Bivariate and multivariate analyses of risk factors were assessed on RTSA patients from the ACS-NSQIP database from 2011 to 2015. Patients were risk-stratified and timing of severe adverse events and cause of readmission were evaluated. Results Of 809 RTSA patients, 61 suffered a perioperative complication or readmission within 30 days of discharge. Multivariate analysis identified operative time, BMI > 40, infection etiology, high white blood cell count, and low hematocrit as significant independent risk factors for 30-day complications or readmission after RTSA (p ≤ 0.05). Having at least one significant risk factor was associated with 2.71 times risk of complication or readmission within 15 days compared to having no risk factors (p < 0.001). The majority of unplanned readmission, return to the operating room, open/deep wound infection, and sepsis/septic shock occurred within two weeks of RTSA. Discussion Patients at high risk of complications and readmission after RTSA should be identified and optimized preoperatively to improve outcomes and lower costs.
A Comparison of Two Designs of Postoperative Shoe on Function, Satisfaction, and Back Pain After Hallux Valgus Surgery
Authors: Patel Shelain , Garg Parag , Fazal M. Ali , Shahid Muhammad S. , Park Derek H. , Ray Pinak S. 
Published: June 2018

Background. The reverse camber shoe is commonly used after hallux valgus corrective surgery to offload the forefoot but is associated with back pain and poor compliance. Recent designs of postoperative shoes may obviate the need for a reverse camber. The purpose of this study was to compare the effects of a reverse camber shoe and a noncambered shoe with transitional rigidity after hallux valgus correction. Methods. A cohort of 80 feet was prospectively studied undergoing surgery at a single NHS trust. The first 40 feet received the reverse cambered Jura Medical Off-loader Heel shoe and the subsequent 40 feet received the noncambered DonJoy Podalux shoe. No demographic differences existed between the groups and data were collected at 2 weeks, 6 weeks, and 6 months. The Manchester-Oxford Foot Questionnaire (MOXFQ), a 5-question survey and dichotomous question about back pain was used to assess clinical outcome and radiographs were reviewed by 2 orthopaedic surgeons to monitor for loss of correction. Results. Both groups experienced comparable improvements in MOXFQ and shoe satisfaction from 2 weeks compared with 6 weeks. Six patients experienced back pain in the reverse cambered shoe group and none in the noncambered shoe group. Five patients stopped using the reverse cambered shoe during the first 6 weeks after surgery and none stopped using their prescribed noncambered shoe. No loss of corrections were observed in either group. Conclusion. Both shoe designs gave equal foot specific functional and radiological outcomes, but the noncambered shoe with transitional rigidity was associated with less back pain and better compliance. Levels of Evidence: Level II: Prospective comparative study
Increased posterior cingulate cortex efficiency may predict cognitive impairment in asymptomatic HIV patients
Authors: Ventura Nina , Douw Linda , Correa Diogo G , Netto Tania M , Cabral Rafael F , Lopes Fernanda Cristina Rueda , Gasparetto Emerson L 
Published: June 2018

Purpose Despite antiretroviral therapy, approximately half of individuals with human immunodeficiency virus (HIV) will develop HIV-associated neurocognitive disorder (HAND). Efficiency of brain networks is of great importance for cognitive functioning, since functional networks may reorganize or compensate to preserve normal cognition. This study aims to compare efficiency of the posterior cingulate cortex (PCC) between patients with and without HAND and controls. We hypothesize HAND negative (HAND–) patients will show higher PCC efficiency than HAND positive (HAND+) patients. Methods A total of 10 HAND + patients were compared with 9 HAND– patients and 17 gender-, age-, and education-matched controls. Resting-state functional MRI was acquired with a 3 Tesla scanner. Local efficiency, a measure of network functioning, was investigated for PCC. Network differences among HAND + , HAND– patients and controls were tested as well as correlations between network parameters and cognitive test performance in different domains. Results HAND– patients showed significantly increased PCC efficiency compared with healthy controls ( p = 0.015). No differences were observed between HAND + patients and either controls ( p = 0.327) or HAND– patients ( p = 0.152). In HAND– patients, PCC efficiency was positively related with cognitive performance in the attention/working memory domain ( p = 0.003). Conversely, in HAND + patients, PCC efficiency was negatively correlated with performance in the abstraction/executive domain ( p = 0.002). Conclusion HAND– patients showed a higher level of PCC efficiency compared with healthy subjects, and PCC efficiency was positively related to cognitive performance. These results support the functional reorganization hypothesis, that increased PCC efficiency is a compensation technique to maintain cognitive functioning.
Reference intervals of thyroid hormones in a previously iodine-deficient area in Darfur, Sudan
Authors: Ali Nagi I. , Alamoudi Abdullah O. , Adam Ishag 
Published: June 2018

Background: Thyroid-stimulating hormone (TSH), thyroxin (T4) and T3 levels are varied in the different settings with disorders of thyroid homeostasis. It is recommended that every setting has to establish its own reference intervals (RIs) for these hormones. Methods: A multi-stage stratified sampling method was used to select a representative sample of a Sudanese adult (>20 years of age) in Nyala in western Sudan in the Darfur region during the period between January and June 2016 to establish RIs of thyroid-related hormones (TSH, T4 and T3). In this study, 1753 serum samples (male and female) with different age groups were investigated. A radioimmunoassay gamma counter was used to measure the level of these hormones. Results: The median (95% intervals) of serum TSH, T4 and T3 levels was 1.2 (0.50–3.0) mIU/l, 111.0 (72.0–161.0) nmol/l and 1.5 (0.8–2.8) nmol/l respectively. While the level of TSH was significantly higher in the age group between 31 and 40 years, both T4 and T3 levels have shown a progressive increase with age. There was no significant difference in the TSH, T4 and T3 level when the RIs were compared between males and females. Conclusion: The RIs for TSH, T4 and T3 in this setting were different from the levels provided by the manufacturers. The RIs were different in the different age groups.
Do primary care providers who prescribe more opioids have higher patient panel satisfaction scores?
Authors: North Frederick , Crane Sarah J , Ebbert Jon O , Tulledge-Scheitel Sidna M 
Published: June 2018

Objectives: Opioid prescribing in the United States has tripled since 1999. At the same time, there has been increasing attention to patient satisfaction. It has been suggested that providers concerned about patient satisfaction may be more likely to treat pain with opioids. We examined primary care providers’ opioid prescribing practices to determine if higher provider opioid prescribing was associated with higher patient satisfaction. Methods: For 77 primary care providers, we compared each provider’s opioid prescription count and amount prescribed to each provider’s patient panel satisfaction measures. Satisfaction measures were obtained from surveys following office visits and consisted of Likert-type scale answers concerning satisfaction for pain management and other provider satisfaction domains. Satisfaction surveys were generated independent of patient complaint of pain and had the aim of overall assessment of patient satisfaction with the provider and the healthcare system. We assessed the correlation between opioid prescribing and patient panel pain management satisfaction using linear regression models with and without adjustment for patient complexity. Results: We observed no statistically significant correlation between patient panel satisfaction with their provider and the quantity of opioids that the provider prescribed (R2 = 0.006; p = 0.52). There was also no correlation between patient panel satisfaction and the number of opioid prescriptions written by their provider (R2 = 0.005; p = 0.54). Additional multivariate analysis after adjusting for patient complexity also demonstrated no correlation of pain management satisfaction with opioids prescribed. Although the quantity of opioid prescriptions was not correlated with pain management satisfaction, several other patient satisfaction measures correlated significantly with pain management satisfaction. Conclusion: Primary care providers with a greater rate of opioid prescribing did not have higher patient panel satisfaction scores for pain management. In primary care, providers who want to improve patient satisfaction should focus on other components of patient care besides opioid-based pain management.