bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of urban flood hazards and adaptation strategies in the Tamale Metropolis of Ghana
Authors: Ampofo Justice Agyei , Owusu-Sekyere Ebenezer , Adongo Raymond 
Published: February 2025

Abstract
The study examines urban flood risk and adaptation strategies in the Tamale Metropolitan area of Ghana. Geospatial techniques were employed to map flood-prone communities, while questionnaires were used to gather data from residents on flood adaptation strategies. The Kendall coefficient of concordance was applied to rank the effectiveness of the various adaptation measures. The results revealed that communities with a topographic wetness index (TWI) between −2.0 and −7.7 were at higher risk of flooding. Factors contributing to flooding included the presence of Ferric Luvisols soil with high clay content, low-lying terrain, significant water flow accumulation, and rapid urbanization, which has increased impervious surfaces. Flood barriers and sandbags were ranked the most effective among the adaptation strategies, followed by early warning systems and community evacuation plans. The findings underscore the need for proactive measures to mitigate the growing vulnerability of residents to flooding. The study argues for incorporating flood risk assessments into zoning regulations to prevent development in high-risk areas and promote a flood-resilient city.
Impact of two antimicrobial susceptibility reporting strategies on treatment of bacteremia caused by low-risk AmpC inducible organisms
Authors: Mashru Jai , Elligsen Marion , Daneman Nick , Granger Marie-Félixe , Kozak Robert A. , Li Xena X. , Leis Jerome A. , Lam Philip W. 
Published: February 2025

Abstract
In this retrospective study examining the treatment of low-risk AmpC-producing Enterobacterales bacteremia during two periods with different microbiology reporting strategies, reporting of ceftriaxone susceptibility was associated with a statistically significant decrease in carbapenem use as definitive therapy compared to when susceptibility was suppressed (21 vs 50%, p < 0.0001).
Coordination of aluminum in saponite-like material as a function of synthesis pH
Authors: Dzene Liva , Dutournié Patrick , Rigolet Séverinne , Vidal Loïc , Lassalle-Kaiser Benedikt , Vantelon Delphine , Paineau Erwan 
Published: February 2025

Abstract
Saponite-like materials have a wide range of potential applications, especially in heterogeneous catalysis. Despite the simplicity of the synthesis, the mechanisms of the formation of saponite are not well understood yet. The aim of the present study was to investigate a possible correlation between the coordination of Al in the solid phase and in the solution. For this, samples were prepared by varying the initial OH:Si molar ratio from 0.18 to 2.14, leading to a pH in the supernatant after the hydrothermal treatment of 6.7 to 12.7, respectively. The characterization of the material was performed by combining nuclear magnetic resonance (NMR) and X-ray absorption near edge structure (XANES) spectroscopies, and good agreement was obtained between the two techniques. Between pH7 and pH10, 60–65% of aluminum was found to be in tetrahedral coordination, while this percentage increased above pH10 (up to 81%). These results correlated with the speciation of the aluminum in aqueous solution. Indeed, above pH10, all available aluminum was in the soluble form Al(OH)4–.
Discourse annotation guideline for low-resource languages
Authors: Vargas Francielle , Schmeisser-Nieto Wolfgang , Rabinovich Zohar , Pardo Thiago A. S. , Benevenuto Fabrício 
Published: February 2025

AbstractMost existing discourse annotation guidelines have focused on the English language. As a result, there is a significant lack of research and resources concerning computational discourse-level language understanding and generation for other languages. To fill this relevant gap, we introduce the first discourse annotation guideline using the rhetorical structure theory (RST) for low-resource languages. Specifically, this guideline provides accurate examples of discourse coherence relations in three romance languages: Italian, Portuguese, and Spanish. We further discuss theoretical definitions of RST and compare different artificial intelligence discourse frameworks, hence offering a reliable and accessible survey to new researchers and annotators.
Yugoslavia is (not) a Refugee Country? Refugees between Transit and Integration in an Ever-Changing Socialist State
Authors: Rolandi Francesca 
Published: February 2025

AbstractThroughout the Cold War, Yugoslavia was the only socialist country that participated in the Western-led international refugee regime and acted as a transit zone for refugees hoping to reach the Western Bloc. Those transiting were mainly, but not exclusively, escapees from various countries in the Soviet bloc. A few refugee groups also settled in Yugoslavia against the backdrop of shifts in international constellations, tense relationships with neighboring countries, and transnational mobilizations. This article will first investigate the dichotomy between transit and the few instances of refugees integrating into socialist Yugoslavia. Next, it will investigate the ease of the resettlement process by exploring how the length of time spent in the country was influenced by hierarchies among different refugee groups based on ethnic origin, political allegiances, class, and which opportunities for resettlement were available to whom. Finally, it will reflect on how the changing role of temporary refuge or permanent haven that Yugoslavia ascribed to itself was constructed and challenged by the host society, potential countries of resettlement, and the refugees themselves.
Pandemic masculinity: urban low-income men and the Covid-19 pandemic in Nigeria
Authors: Izugbara Chimaraoke 
Published: February 2025

AbstractIn studies of violence against women and children during the Covid-19 pandemic, as well as in explanations of men’s increased vulnerability to the disease, the concept of ‘toxic masculinity’ regularly surfaces. However, direct research on men’s perspectives on the pandemic’s impact on them as men remains scarce. Drawing on interview data on urban Nigerian men’s lived experiences and narratives of the epidemic in relation to their identities and roles as men, I explore whether toxic masculinity was emblematic of men’s responses to the Covid-19 socio-economic crisis. While I found little evidence of the men’s reliance on toxic masculine practices to maintain their identities as men during the pandemic, their accounts revealed something quite significant: the reconstitution of masculine success in terms of the ability to adjust to the times by discontinuing practices that, while once essential to their identity as men, now threatened their image as capable providers. These adjustments, which frequently involved resorting to practices that would be considered unmanly, were constituted as part of the routine situational pivots that ‘real’ men must make, in keeping with their role as all-weather providers. I conclude with a reflection on how so-called non-heteronormative male performances might still mask gender inequalities and perpetuate certain aspects of patriarchal power.
Assessing the Association Between the Mediterranean, DASH, and MIND Dietary Patterns, Structural Connectivity, and Cognitive Function
Authors: Arnoldy Lizanne , Gauci Sarah , Young Lauren M. , Macpherson Helen , Civier Oren , Scholey Andrew , Pipingas Andrew , White David J. 
Published: February 2025

Abstract
The rising incidence of neurodegenerative diseases in an ageing global population has shifted research focus toward modifiable risk factors, such as diet. Despite potential links between dietary patterns and brain health, inconsistencies in neuroimaging outcomes underscore a gap in understanding how diet impacts brain ageing. This study explores the relationship between three dietary patterns—Mediterranean (MeDi), Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND)—and cognitive outcomes as well as brain connectivity. The study aimed to assess the association of these diets with brain structure and cognitive function, involving a middle-aged healthy group and an older cohort with subjective cognitive decline (SCD). The study included cognitive assessments and diffusion-weighted MRI data to analyse white matter microstructural integrity. Participants comprised 55 older individuals with SCD (54.5% female, mean age = 64) and 52 healthy middle-aged individuals (48.1% female, mean age = 53). Age inversely correlated with certain cognitive functions and global brain metrics, across both cohorts. Adherence to the MeDi, DASH, and MIND diets showed no significant cognitive or global brain metric improvements after adjusting for covariates (age, education, BMI). Network-based statistics (NBS) analysis revealed differences in brain subnetworks based on DASH diet adherence levels in the SCD cohort. In the healthy cohort, lower white matter connectivity was associated with reduced adherence to MIND and DASH diets. Ultimately, the study found no strong evidence connecting dietary patterns to cognitive or brain connectivity outcomes. Future research should focus on longitudinal studies and refine dietary assessments.
Navigating the biosocial: perspectives of early career researchers working with birth cohorts.
Authors: Borra Catherine , Tabor Evangeline , Cole Faith , Stock Sarah 
Published: February 2025

Abstract
In recent years, there have been increasing calls for the development and growth of the biosocial as a paradigm through which to tackle complex problems. The use of birth cohorts, mixed methods frameworks, and interdisciplinary work are common in biosocial research. However, these practices are also theoretically and practically complex due to epistemic, methodological, and academic challenges – particularly for early career researchers (ECRs) who face time constraints, funding limitations, and disciplinary expectations.
This paper draws on lessons from the experiences of ECRs in biosocial research by reflecting on theoretical heterogeneity, the necessity of translation and negotiation across disciplines and methodologies, and the practicalities of funding, collaboration, and dissemination. Throughout, the paper discusses strategies to overcome common challenges and provide suggestions for fellow ECRs and those interested in biosocial ECR training and development. The paper highlights the importance of strong networks with senior biosocial researchers and peers, the value of practical support, and the importance of formal and informal learning opportunities. The authors call for the enthusiasm for biosocial research to be matched with investment in the development and support for ECRs.
The foreign language effect on lies’ perception: Behavioral and electrophysiological evidence
Authors: Xie Shiyu , Liao Xiaogen , Ni Chuanbin 
Published: February 2025

Abstract
Although accumulating evidence has demonstrated the foreign language (FL) effect in various scenarios, it remains underexplored whether the FL effect (FLe) would be modulated by the affective valence of scenarios. Hence, we investigated the FLe on the perception of egoistic lies and altruistic lies behaviorally and electrophysiologically. Behavior results showed that compared to using a native language (NL), using a FL led to more agreement with egoistic lies but a comparable level with altruistic lies. Electrophysiological results showed that skin conductance responses (SCRs) elicited by the truth were stronger in the FL compared to that in the NL, whereas SCRs elicited by lies, although strong, exhibited less sensitivity to the altruistic/egoistic condition. SCRs suggested that increased cognitive thinking and reduced affective thinking may contribute to the FLe on egoistic lies dependently or interactively, but these mechanisms cannot accommodate altruistic lies. The results implied the FLe is more stable and obvious in negative contexts.
Access All Areas: Breaking Down the Barriers to Legal Information
Authors: Sheridan Gavin 
Published: February 2025

AbstractThe decisions of courts and tribunals, and the statutes that societies live under, are the building blocks to the rule of law. Access to this information for legal professionals can be difficult while access for the general public is often impossible. This article by Gavin Sheridan, the co-founder and CEO at Vizlegal, considers a first principles approach to the barriers to access, how the legal industry has adapted, how technology companies can address and improve it and how the future of legal information involves open access, open standards and innovation built on top of legal data.
What leads clinicians to exclude drug and alcohol users from NHS Talking Therapies services? An audit of decision making within clinical records
Authors: Shahriyarmolki Khodayar , Hemingway Rachael L. , Strang Hannah J. 
Published: February 2025

Abstract
Drug and alcohol users have been suggested to face disproportionate exclusion from mental health services, but data on any such exclusion are not readily available. This study examined the clinical records of those excluded from an NHS Talking Therapies service due to drug or alcohol use, focusing on (1) quantitative levels of alcohol consumption, and (2) the rationales documented by clinicians for excluding these individuals. Our results suggest that over half (57%) of those excluded due to alcohol use were consuming below the 15-unit daily threshold recommended for signposting to specialist alcohol assessment. Clinicians cited various rationales for exclusion, including the potential for poor treatment outcomes and health risks associated with concurrent use. Due to being based on a single service, these findings may be limited in their generalisability, but they offer an initial signal that there is potential over-exclusion of some alcohol users from NHS Talking Therapies, and that rationales for exclusion may not consistently align with best practice principles. We discuss implications for NHS Talking Therapies clinicians, and for the development of future clinical guidance.

Key learning aims

(1)
To understand how different levels of drug or alcohol use may affect the outcomes of psychological therapy.

(2)
To learn why individuals with drug or alcohol use experience exclusion from mental health services.

(3)
To examine how clinical practice within an NHS Talking Therapies service aligns with best practice principles.

(4)
To explore skills and clinical principles that can lead to optimal treatment planning for these individuals.

(5)
To explore how integrated working between NHS Talking Therapies and local drug and alcohol services can enhance service-user experiences.
Lactylation-driven transcriptional activation of FBXO33 promotes gallbladder cancer metastasis by regulating p53 polyubiquitination
Authors: Wu Zhenheng , Peng You , Chen Wen , Xia Feng , Song Tieshan , Ke Qiming 
Published: February 2025

Abstract
Gallbladder cancer (GBC) is the most common malignant tumor of the biliary tract and is often prone to early distant metastasis. However, the mechanisms underlying GBC’s invasive metastasis remain unclear. This study identified that F-box only protein 33 (FBXO33) expression is significantly elevated in GBC and is negatively associated with patient prognosis. In vivo and in vitro experiments demonstrated that knockdown of FBXO33 inhibits epithelial-mesenchymal transition (EMT) progression in GBC, while overexpression of FBXO33 promotes EMT progression. Mechanistically, FBXO33 regulates EMT progression by modulating the polyubiquitination of p53 at K291 and K292. Moreover, the upregulation of FBXO33 in GBC is driven by transcriptional regulation mediated by Yin Yang-1 (YY1). The lactylation modification of YY1 at K183 was found to be essential for the transcriptional activation of FBXO33. These findings underscore the role of the lactylation-driven FBXO33-p53 axis in promoting the invasive metastasis of GBC.
Loss of TC-PTP in keratinocytes leads to increased UVB-induced autophagy
Authors: Asare Obed , Shim Lindsey , Lee Cheol-Jung , Delgado Jose , Quailes Natasha , Zavala Klarissa , Park Junsoo , Hafeez Bilal Bin , Cho Yong-Yeon , Chauhan Subhash C. , Kim Dae Joon 
Published: February 2025

Abstract
Ultraviolet B (UVB) radiation can distort cellular homeostasis and predispose the skin to carcinogenesis. Amongst the deteriorating effects of the sun’s UVB radiation on cellular homeostasis is the formation of DNA photoproducts. These photoproducts can cause significant changes in the structure and conformation of DNA, inducing gene mutations which may accumulate to trigger the formation of skin cancer. Photoproducts are typically repaired by nucleotide excision repair. Notwithstanding, when the repair mechanism fails, apoptosis ensues to prevent the accumulation of mutations and to restore cellular homeostasis. This present study reports that T-cell protein tyrosine phosphatase (TC-PTP) can increase UVB-induced apoptosis by inhibiting autophagy-mediated cell survival of damaged keratinocytes. TC-PTP deficiency in 3PC mouse keratinocytes led to the formation of autophagic vacuoles and increased expression of LC3-II. We established human TC-PTP-deficient (TC-PTP/KO) HaCaT cells using the CRISPR/Cas9 system. TC-PTP/KO HaCaT cells exhibited increased cell survival upon UVB exposure, which was accompanied by increased expression of LC3-II and decreased expression of p62 compared to control cells. Pretreatment of TC-PTP/KO HaCaT cells with early-phase autophagy inhibitor, 3-methyladenine significantly decreased the expression of LC3-II and reduced cell survival in response to UVB irradiation in comparison with untreated TC-PTP/KO cells. Pretreatment of TC-PTP/KO HaCaT cells with late-phase inhibitor, chloroquine also significantly reduced cell viability with increased accumulation of LC3-II after UVB irradiation compared to untreated counterpart cells. While UVB significantly increased apoptosis in the engineered (Mock) cells, this was not observed in similarly treated TC-PTP/KO HaCaT cells. However, chloroquine treatment increased apoptosis in TC-PTP/KO HaCaT cells. Examination of human squamous cell carcinomas (SCCs) revealed that TC-PTP expression was inversely correlated with LC3 expression. Our findings suggest that TC-PTP negatively regulates autophagy-mediated survival of damaged cells following UVB exposure, which can contribute to remove damaged keratinocytes via apoptosis.
Pelvic physical therapy for male sexual disorders: a narrative review
Authors: Sahin Emel , Brand Alma , Cetindag Elif Nazli , Messelink Bert , Yosmaoglu Hayri Baran 
Published: February 2025

Abstract
Pelvic physical therapy is an evidence-based, first-line treatment for many pelvic floor disorders and sexual dysfunction. Studies have shown that pelvic physical therapy programs can both improve pelvic floor dysfunctions and sexual function. This article aims to provide an overview of the current state of the art regarding pelvic physical therapy for male sexual dysfunction to inform healthcare providers who treat men with sexual dysfunction better. A literature review was performed in Google Scholar, PubMed, and Science Direct to find review articles, research articles, and case studies about the effect of pelvic physical therapy treatments for male sexual dysfunction. Twenty-six articles were found about various pelvic physical therapy interventions. Besides this overview of the literature, an overview of interventions used in clinical practice is also provided. This narrative review supports the potential efficacy of pelvic physical therapy in addressing male sexual dysfunction. Pelvic physical therapy approaches that comprise exercise modalities, electrotherapy approaches, manipulative techniques, lifestyle changes, behavioral suggestions, and pain management strategies, should be suggested for potential benefits in improving erectile function, premature ejaculation, and sexual dysfunction-associated chronic pelvic pain. More research is needed to examine the effect of pelvic physical therapy on hypoactive sexual desire and delayed ejaculation.
Pupil size reveals arousal level fluctuations in human sleep
Authors: Carro-Domínguez Manuel , Huwiler Stephanie , Oberlin Stella , Oesch Timona Leandra , Badii Gabriela , Lüthi Anita , Wenderoth Nicole , Meissner Sarah Nadine , Lustenberger Caroline 
Published: February 2025

Abstract
Recent animal research has revealed the intricate dynamics of arousal levels that are important for maintaining proper sleep resilience and memory consolidation. In humans, changes in arousal level are believed to be a determining characteristic of healthy and pathological sleep but tracking arousal level fluctuations has been methodologically challenging. Here we measured pupil size, an established indicator of arousal levels, by safely taping the right eye open during overnight sleep and tested whether pupil size affects cortical response to auditory stimulation. We show that pupil size dynamics change as a function of important sleep events across different temporal scales. In particular, our results show pupil size to be inversely related to the occurrence of sleep spindle clusters, a marker of sleep resilience. Additionally, we found pupil size prior to auditory stimulation to influence the evoked response, most notably in delta power, a marker of several restorative and regenerative functions of sleep. Recording pupil size dynamics provides insights into the interplay between arousal levels and sleep oscillations.
Unsupervised identification of crystal defects from atomistic potential descriptors
Authors: Kývala Lukáš , Montero de Hijes Pablo , Dellago Christoph 
Published: February 2025

Abstract
Identifying crystal defects is vital for unraveling the origins of many physical phenomena. Traditionally used order parameters are system-dependent and can be computationally expensive to calculate for long molecular dynamics simulations. Unsupervised algorithms offer an alternative independent of the studied system and can utilize precalculated atomistic potential descriptors from molecular dynamics simulations. We compare the performance of three such algorithms (PCA, UMAP, and PaCMAP) on silicon and water systems. Initially, we evaluate the algorithms for recognizing phases, including crystal polymorphs and the melt, followed by an extension of our analysis to identify interstitials, vacancies, and interfaces. While PCA is found unsuitable for effective classification, it has been shown to be a suitable initialization for UMAP and PaCMAP. Both UMAP and PaCMAP show promising results overall, with PaCMAP proving more robust in classification, except in cases of significant class imbalance, where UMAP performs better. Notably, both algorithms successfully identify nuclei in supercooled water, demonstrating their applicability to ice nucleation in water.