bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kidney Support in Children using an Ultrafiltration Device
Authors: Menon Shina , Broderick John , Munshi Raj , Dill Lynn , DePaoli Bradley , Fathallah-Shaykh Sahar , Claes Donna , Goldstein Stuart L. , Askenazi David J. 
Published: August 2019

Background and objectives
Provision of kidney replacement therapy (KRT) to manage kidney injury and volume overload in critically ill neonates and small children is technically challenging. The use of machines designed for adult-sized patients, necessitates large catheters, a high extracorporeal volume relative to patient size, and need for blood priming. The Aquadex FlexFlow System (CHF Solutions Inc., Eden Prairie, MN) is an ultrafiltration device designed for fluid removal in adults with diuretic resistant heart failure. It has an extracorporeal volume of 33 ml, which can potentially mitigate some complications seen at onset of KRT in smaller infants.

Design, setting, participants, & measurements
In this multicenter, retrospective case series of children who received KRT with an ultrafiltration device (n=119 admissions, 884 circuits), we report demographics, circuit characteristics, complications, and short- and long-term outcomes. Patients were grouped according to weight (<10, 10–20, and >20 kg), and received one of three modalities: slow continuous ultrafiltration, continuous venovenous hemofiltration (CVVH), or prolonged intermittent KRT. Our primary outcome was survival to end of KRT.

Results
Treatment patterns and outcomes varied between the groups. In patients who weighed <10 kg, the primary indication was AKI in 40%, volume overload in 46%, and ESKD in 14%. These patients primarily received CVVH (66%, n=48) and prolonged intermittent KRT (21%, n=15). In the group weighing >20 kg, volume overload was the primary indication in 91% and slow continuous ultrafiltration was the most common modality. Patients <10 kg had lower KRT survival than those >20 kg (60% versus 97%), more volume overload at onset, and received KRT for a longer duration. Cardiovascular complications at initiation were seen in 3% of treatments and none were severe. Complications during therapy were seen in 15% treatments and most were vascular access–related.

Conclusions
We report the first pediatric experience using an ultrafiltration device to provide a range of therapies, including CVVH, prolonged intermittent KRT, and slow continuous ultrafiltration. We were able to initiate KRT with minimal complications, particularly in critically ill neonates. There is an unmet need for devices specifically designed for younger patients. Having size-appropriate machines will improve the care of smaller children who require kidney support.
Amor y chavismo: espacio público y propaganda en el Socialismo del siglo XXI
Authors: Arteaga Mora Carmen Geraldine 
Published: August 2019

<p>Se aborda el uso del tópico «amor» como recurso propagandístico del chavismo, bajo la hipótesis de que existe un esfuerzo orientado a fomentar la creación de una meta-realidad ideológica, para legitimarse en el poder, a partir de la afectividad vinculante entre la figura de Hugo Chávez y las masas. Desde esta perspectiva, Chávez es representado como un Héroe místico, a quien “su” Pueblo debe corresponderle incondicionalmente. Consecuentemente, se descarta el principio de rendición de cuentas y eficiencia en la gestión gubernamental, en función del respaldo de la población a un liderazgo que reviste carácter divino. Mediante el análisis de representaciones simbólicas presentes en el discurso e iconografía pública, se plantea que el Socialismo del Siglo XXI concuerda con los rasgos del un proyecto totalitario, y que desarrolla un imaginario que a su vez opera por una parte, enmascarando discursivamente las prácticas represivas y autoritarias características de este movimiento y por otra, fundando la legitimidad sobre un fin trascendental de carácter cuasi místico. La pregunta abierta es si el tópico amoroso será suficiente para compensar el agotamiento del Socialismo del Siglo XXI en la etapa post Chávez, y cuando Nicolás Maduro pareciera retroceder en términos de legitimidad política.</p>
BNCC e privatização da Educação Infantil: impactos na formação de professores
Authors: Campos Roselane De Fátima , Durli Zenilde , Campos Rosânia 
Published: August 2019

A formação de professores é estratégica nos processos de mudanças educacionais e, mais fortemente, quando elas se referem às práticas pedagógicas nas escolas. Entre 2009 a 2017, iniciativas governamentaisobjetivaram instituir uma política nacional de formação de profissionais do magistério da educação básica e, com a aprovação da BNCC em 2017, foi estabelecida a articulação entre dois pilares – currículo e formação – como condição necessária ao desenvolvimento de uma educação de qualidade. Neste artigo, analisamos as orientações governamentais para a implementação da BNCC, procurando evidenciar a ação de redes empresariais que se constituíram, nos últimos três anos, nos principais interlocutores do governo e destacar as estratégias empresariais de formação continuada dirigidas, em particular, para profissionais da educação infantil.
reemergencia de fundamentalismos islámicos y judios
Authors: Caro Isaac 
Published: August 2019

En este artículo se presentan a los movimientos religiosos fundamentalistas en cuanto nuevos actores del sistema internacional posguerra fría. Se enfatiza que los fundamentalismos islámicos y judíos adoptan múltiples formas y medios: en algunas circunstancias se trata de un fenómeno más moderado, mientras que en otras es más violento. Existen múltiples actores, tanto estatales como no estatales, los que responden a características sociales, políticas y culturales propias de cada una de las diferentes áreas, naciones y contextos históricos en que éstos se desarrollan. Se señala que los componentes de los movimientos más radicales es su intolerancia y rechazo hacia aquellos que no forman parte del grupo de pertenencia. Este fanatismo religioso – que comparten grupos fundamentalistas islámicos y judíos - se ha acentuado a raíz de los últimos sucesos en el conflicto israelí – palestino. Finalmente, se examina el impacto de los fundamentalismos islámicos en algunos países de América Latina.
RELAÇÕES ENTRE CULTURA E ENSINO: um olhar discursivo sobre as políticas públicas para formação de professores
Authors: De Nardi Fabiele Stockmans , Balzan Fabíola Ponzoni 
Published: August 2019

Notre but dans cet article est d’observer la notion de culture mobilisée dans un document sur le programme destiné aux enseignants des écoles élémentaires. Le point de départ est une discussion de la notion de culture, que nous avons pris comme un lieu d’interpretation, pour observer les contradictions qui traversent la proposition même de culture, parfois en réaffirmant son caractère dynamique, parfois en supposant des mouvements de neutralisation dans ces relations entre la culture et les environnements éducatifs. Cette analyse permet de réaffirmer la complexité de la relation entre le sujet et la culture, surtout quand on considere la place destinée à la culture dans les processus d’ensegnement et d’apprentissage, et permet aussi une réflexion sur les relations de pouvoir impliquées dans le développement de la construction des connaissances.
ELLIS, Nick C.; LARSEN-FREEMAN, Diane. (ed.) Language as a Complex Adaptive System. In: Language Learning, n. 59, Suppl. 1, Dezembro 2009, 275p.
Authors: Da Silva Leandra Fagundes , Rodrigues Lisandra 
Published: August 2019

ELLIS, Nick C.; LARSEN-FREEMAN, Diane. (ed.) Language as aComplex Adaptive System. In: Language Learning, n. 59, Suppl. 1,Dezembro 2009, 275p. Resenhado por Leandra Fagundes da Silva e Lisandra Rutkoski Rodrigues
MEMÓRIA DA LÍNGUA E ENSINO: MODOS DE APARECIMENTO DE UMA LÍNGUA APAGADA NO TRABALHO DO ESQUECIMENTO
Authors: Payer Maria Onice 
Published: August 2019

L’article expose le fonctionnement actuel de la mémoire de lalangue des sujets immigrants, en considérant la réduction au silence deleur langue maternelle dans l’histoire brésilienne. Notre but est decomprendre la relation entre le sujet et la langue, dans la rencontre entrela langue nationale et la langue maternelle. Cette question a trait à laconnaissance des processus de subjetivation qui se présentent dansl’enseignement de la (des) langue(s) et également dans la relation pluslarge de la société avec elle(s), soit par le biais de la mémoire, soit parcelui de l’oubli. On y aborde certains aspects de la relation sujet/languequi se manifestent à travers le rire dans l’énonciation d’une langue réduiteau silence; du chanter dans cette langue; à travers la survalorisation desformes considérées comme correctes de la langue nationale, et aussi ladénégation (méconaissance) de la présence d’autres langues dans lamémoire linguistique des locuteurs - quand en fait leurs traces sontprésentes dans la pratique langagière. En ce sens, il n’est pas suffisantd’enseigner des langues réduites au silence dans les régionsd’immigration, comme il le semble à première vue. On soutientl’importance d’un effectif travail de mémoire dans le sujet, pour la compréhension de la dimension discursive, telle qu’elle se présente dansla situation historique de l’immigration au Brésil.
HARMONIZAÇÃO VOCÁLICA: EFEITO PARCIAL E TOTAL
Authors: Bisol Leda 
Published: August 2019

0 propósito deste texto é comparar os efeitos de harmonização vocálica, um processo de assimilação regressiva, em duas variedades do português brasileiro, uma com cinco vogais átonas, outra com sete. O processo consiste em mudar a vogal média em alta diante de uma sílaba com vogal alta. A condição de adjacência é observada em ambas as variedades, mas somente a última mostra efeitos de mudança gradiente.
Evaluasi Penggunaan Antibiotik pada Pasien Bedah Caesar dan Hernia di Salah Satu Rumah Sakit di Jawa Barat
Authors: Nuraliyah Nisa Maulani , Ramadhania Zelika Mega , Syofiah Eni 
Published: August 2019

Antimikroba mempunyai peranan besar dalam penanganan penyakit infeksi, namun adanya penggunaan yang tidak tepat dan berlebihan memicu terjadinya resistensi. Salah satu yang paling umum adalah resistensi terhadap antibiotik. Di rumah sakit, antibiotik banyak digunakan untuk penanganan penyakit infeksi maupun pada prosedur bedah sebagai profilaksis. Merujuk pada Peraturan Menteri Kesehatan Nomor 8 tahun 2015 tentang Program Pengendalian Resistensi Antimikroba dan bahwa penggunaan antibiotik di rumah sakit harus dikendalikan, salah satu bentuk pengendalian adalah melalui evaluasi penggunaan antibiotik. Tujuan dari penelitian ini adalah mendapatkan gambaran penggunaan antibiotik pada pasien bedah Caesar dan hernia di Rumah Sakit Al Islam periode September – November 2018. Evaluasi penggunaan antibiotik dilakukan dengan metode penilaian Defined Daily Dose (DDD)/100 hari rawat. Hasil evaluasi menunjukan antibiotik yang paling banyak digunakan adalah sceftriaxone dengan nilai 32.95 DDD/100 hari rawat pada bedah hernia dan 62.58 DDD/100 hari rawat untuk bedah caesar.Kata kunci: antibiotik, ATC/DDD, evaluasi
Impact of genetics on neoadjuvant therapy with complete pathological response in metastatic colorectal cancer: Case report and review of the literature
Authors: Bulajic P , Bidzic N , Djordjevic V , Ceranic Μ , Βasaric D , Pesic V , Djordjevic-Pesic J 
Published: August 2019

Abstract
Treatment of colorectal metastatic cancer is still challenging, despite recent improvements in chemotherapy. A genetic cancer profile, such as the KRAS (Kirsten rat sarcoma) gene status, plays a key role in individualized tailored therapy. Molecular targeted therapy added to neo-adjuvant chemotherapy can achieve a better pathological response and prolong survival. Pathological complete response of colorectal cancer stage IV is rare. A 47-year-old female patient presented with rectal adenocarcinoma and three liver metastases (cT3d/4, N2, Ml). After seven cycles of Bevacizumab and CAPOX in neoadjuvant setting, we noted more than 70.0% regression of metastases and complete regression of the primary tumor. We performed low anterior resection of rectum and synchronous subsegmental resection of S3, because the other two lesions were not detectable. Pathology revealed complete response of the primary and also secondary tumors. After 8 months, diagnostic tests did not show any sign of recurrence and the remaining liver lesions disappeared. Colorectal cancer is a heterogeneous disease and it is necessary to identify patients who are at-risk of recurrence and suitable for neoadjuvant therapy. Genetic biomarkers play an important role in metastatic colorectal cancer treatment. Because of the mutated KRAS gene, Bevacizumab was added to cytotoxic therapy achieving a complete pathological response of primary tumor and metastasis. This case is unique because all reported cases with similar results, described staged surgery and one of reverse staged surgery, but with similar results. This neoadjuvant therapy has extraordinary results for colorectal cancer stage IV and can help disease-free and long-term survival.
Copy number variations in female infertility in China
Authors: Huang W , Wang J , Pang M , Zhao Q , Kong L , Mao Y , Li W , Liang Β 
Published: August 2019

Abstract
Copy number variation (CNV) is a main cause of male infertility, yet its influence still remains elusive in that of females. To investigate the correlation between CNV and female infertility, we applied whole-genome CNV analyses by next generation Sequencing (NGS), and analyzed 324 female infertility samples in Xinjiang Province, People's Republic of China. We identified 29 CNVs in total, of which 10 were novel CNVs. We found these CNVs mostly in chromosome X. The CNVs from one sample overlapped the POF1B gene that was related to premature ovarian failure (POF). The rest of these CNVs overlapped important functional genes related to neuropathy, brain, skin and retina, and the relationship between these CNVs and fertility needs to be studied further. We also found recurrent CNVs located on Xp22.31 and 22ql 1.21 in five and three cases, respectively. Our study first identified and characterized CNVs (CNVs preference, recurrent CNVs) in female infertility, also provided genetic evidence and references for future study and infertility etiology research.
Oxidative Stress in Hemodialysis Patients: Pathophysiological Mechanisms, Clinical Consequences and basic Principles of Treatment
Authors: Antic Svetlana , Draginic Nevena , Nikolic Tomislav , Jeremic Nevena , Petrovic Dejan 
Published: August 2019

Abstract
Microinflammation is a non-traditional risk factor for the development of cardiovascular diseases in patients on hemodialysis. It occurs in 30–50% of these patients, and its main causes are: uremic toxins, oxidative stress, metabolic acidosis, vitamin D deficiency, overhydration, altered intestinal microbiome, impaired intestinal epithelial barrier integrity, increased translocation of endotoxin from the intestinal lumen into the systemic circulation, occult infection of the vascular approach for hemodialysis, periodontal disease, bioincompatibility of the hemodialysis membrane and the presence of endotoxin in the hemodialysis solution. The main clinical consequences of microinflammation are: accelerated atherosclerosis, malnutrition, anemia, resistance to the action of erythropoietin, hemoglobin variability and dialysis-related amyloidosis. Postdilution online hemodiafiltration, extended and adsorptive hemodialysis prevent the development of microinflammation. Optimal control of microinflammation prevents the development of cardiovascular diseases, improves the quality of life and the outcome of patients who are treated with regular hemodialysis.
Call for Papers: “Local Action, Global Impact: From Domination to Partnership”
Authors: Editors IJPS 
Published: August 2019

The Interdisciplinary Journal of Partnership Studies publishes a themed issue each fall. The theme for 2018 is "Local Action, Global Impact: From Domination to Partnership." The theme reflects the growing understanding that global changes often begin when people take action locally. The partnership community around the globe is involved in creative community-based actions that promote mutual respect, social and economic justice, and gender and environmental balance. It is time for us to share insights about this work so that we may empower others to follow.
The editors invite researchers, scholars, and community leaders to submit original articles for its October 2018 issue. The deadline is September 1st.
Professional Identity Formation Among College Premedical Students: A Glimpse into the Looking Glass Using a Career Eulogy Reflective Exercise
Authors: Crump William J. , Fricker R. Steve , Crump Allison M. 
Published: August 2019

Introduction
Pre-medical students are at the very beginning of their formation of a professional identity as a physician. Working with these students early in their education can help them appreciate the importance of professional identity formation as well as inform educators on best methods to understand this process.
Methods
A reflective exercise was used at the beginning of sessions with pre-medical students at their home campus who attended a medical school presentation on the admissions process. Students were asked to reflect on what they wished to be said about them at the end of their career in the form of a “Career Eulogy.” A simple form was developed and administered to the students to capture their reflective writing and their basic demographics anonymously. Qualitative data were blinded and then coded into clusters by the authors using an iterative process.
Results
Reflections from 79 pre-medical students indicated a preference to be remembered for quality and excellence in care, especially among upper level students and students from small towns. Compassion, patient relationships, and the doctor as teacher terms were more likely to be written by Juniors and Seniors while Freshmen and Sophomores tended to focus on terms related to enjoyment of life and service.
Discussion
This reflective exercise provided useful insight into professional identity formation among these college pre-meds and could be used with larger, more diverse groups to determine its value and clarify true differences among the demographic characteristics. Involving similar pre-medical students in focus group settings could also further assist with interpretation of the meaning of these reflections.
Funding/Support: None.
Human Subjects: This study was determined exempt by the Baptist Health Madisonville Institutional Review Board.
Conflicts of Interest: None
FRONTEIRAS DE RESPONSABILIDADE DO PRONAF: LÓGICA DE INTERVENÇÃO, AVALIAÇÕES E SUGESTÕES DE POLÍTICA
Authors: Guanziroli Carlos Enrique 
Published: August 2019

Esse artigo procura efetuar uma avaliação da eficiência e eficácia do PRONAF (Programa de Fortalecimento da Agricultura Familiar) em gerar renda e melhoria de condições de vida para os agricultores familiares nos últimos vinte anos.Trata-se de saber qual seria a fronteira de responsabilidade do PRONAF crédito. O crédito contribui com a eliminação da pobreza rural? A hipótese central é que não pode se exigir que o crédito cumpra objetivos tão ambiciosos. A pobreza rural tem caráter multidimensional, que abrange questões relacionadas ao capital circulante, e que para ser efetiva, precisa que condições prévias estejam presentes, tais como acesso a infraestrutura social e produtiva.Este artigo encontra evidencias nesse sentido compilando e avaliando um total de 35 avaliações feitas na última década sobre o assunto e divulgadas pela SOBER.
Comentario a José María Rojas y María Teresa Findji: Territorio, economía y sociedad Páez
Authors: Fals Borda Orlando 
Published: August 2019

Este trabajo lo considero no sólo de alta calidad cientifíca y original por cuanto investiga en una región y cultura poco conocidas, sino por la utilidad potencial que tiene para la defensa de los intereses de la propia comunidad estudiada.
La obra está concebida y presentada según los más estrictos cánones de análisis de datos primarios y secundarios, con la adición de información derivada de la tradición oral y la memoria colectiva que no son de uso frecuente entre historiadores académicos. Ello se expresa en un texto interesante y rico, en multiplicidad de cuadros, notas de pie de página, mapas y bibliografía pertinente, está construida de manera correcta y completa.
Pequeñas patrias en la tormenta: Pasto y Barbacoas a finales de la colonia y en la Independencia
Authors: Minaudier Jean Pierre 
Published: August 2019

Artículo de investigación relacionado con la historia regional de Nariño entre los años 1750 y 1830, así como el papel que desempeñó Pasto en las guerras de la independencia
Memoria sobre las antigüedades Neogranadinas; del autor: Ezequiel Uricoechea
Authors: Ordoñez Luis A. 
Published: August 2019

Reseña crítica sobre la trayectoria intelectual del autor: Ezequiel Uricoechea, principalmente a una de sus obras ligadas, al rescate de la memoria histórica y diversos elementos culturales presentes en diversas comunidades indígenas.
A los lectores
Authors: Espacio Historia y 
Published: August 2019

En este apartado encontrarás preguntas y respuestas relacionadas a: ¿Cómo publicar una revista especializada en Colombia y no morir en su intento?, y ¿Qué grupos intervienen para dicho fin?, mostrándose los objetivos y alcances que tiene la Revista: Historia y Espacio, dentro del ámbito académico e intelectual.
Mucho ruido y pocas nueces: a propósito de la explotación política de la explosión de Cali en agosto de 1956
Authors: Ayala Diago César Augusto 
Published: August 2019

Artículo encaminado a mostrar las causas y la magnitud del desastre ocasionado por la explosión de los caminones que transportaban dinamita (1956) en la ciudad de Cali, así como su incidencia en el plano político.
Apolinar Díaz Calleja. Colombia – Estados Unidos (Entre la autonomía y la subordinación. De la Independencia a Panamá)
Authors: Loaiza Cano Gilberto 
Published: August 2019

Reseña crítica elaborada por el profesor Gilberto Loaiza Cano, referente al libro: Colombia – Estados Unidos (entre la autonomía y la subordinación. De la Independencia a Panamá), esrita por el autor: Apolinar Díaz Calleja, en relación a la reconstrucción histórica de Colombia, que remonta a los inicios del siglo XIX pasando por los intentos fallidos en cuanto a la integración de la Gran Colombia, y la posterior subordinación que se tuvo respecto otras naciones, como el caso de los Estados Unidos; siendo la separación de Panama una muestra de la intervención extranjera en el plano diplomático nacional.
Lucien Sève. Commencer par les fins.
Authors: Paredes Alcibiades , Flórez Gallego Lenín 
Published: August 2019

Reseña elaborada por los profesores: Alcibiades Paredes y Lenín Flórez Gallego, en relación al libro: Commencer par les fins, del autor, Lucien Sève; enfocado en aspectos del comunismo que confrontan la realidad actual, tales como: «el socialismo de mercado, y la abolición del mercado», el comunismo «post-mercantil» entre otros, ejemplo, el que que tiene que ver a la noción de desarrollo integral de todos los individuos.
Julio Cotler y Romeo Grampone: El fujirismo: ascenso y caída de un régimen autoritario. Instituto de Estudios Peruanos. Lima, 2000.
Authors: Lenis Castillo Paola Andrea , Rendón Fernández Katherine , Restrepo Cárdenas Giselle 
Published: August 2019

El libro, El fujirismo: ascenso y caída de un régimen autoritario, es una obra de análisis sociológico de la historia política peruana de los últimos años, que sigue el orden cronológico de los acontecimientos y utiliza un lenguaje sencillo accesible al público en general, sin con ello restarle rigurosidad al estudio.
Ambos autores explican el proceso de formación, consolidación y caía del régimen autoritario desde diferentes perspectivas y enfoques. Esbozan además algunos elementos que deben tenerse en cuenta para la actual transición democrática.