bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers and facilitators involved in standardised care plan individualisation process in acute hospitalisation wards: A grounded theory approach
Authors: Castellà‐Creus Mònica , Delgado‐Hito Pilar , Casanovas‐Cuellar Cristina , Tàpia‐Pérez Marta , Juvé‐Udina Maria‐Eulàlia 
Published: September 2019

AbstractObjectiveTo identify and classify the barriers and facilitators of the individualisation process of the standardised care plan in hospitalisation wards.BackgroundThe administration of individualised care is one of the features of the nursing process. Care plans are the structured record of the diagnosis, planning and evaluation stages of the nursing process. Although the creation of standardised care plan has made recording easier, it is still necessary to record the individualisation of the care. It is important to study the elements that influence the individualisation process from the nurses' perspective.DesignQualitative study with the grounded theory approach developed by Strauss and Corbin.MethodsThirty‐nine nurses from three hospitals participated by way of theoretical sampling. In‐depth interviews were conducted, as well as participant observation, document analysis and focus group discussion. The analysis consisted of open, axial and selective coding until data saturation was reached. EQUATOR guidelines for qualitative research (COREQ) were applied.ResultsFor both barriers and facilitators, three thematic categories emerged related to organisational, professional and individual aspects. The identified barriers included routines acquired in the wards, the tradition of narrative records, lack of knowledge and limited interest in individualisation. The identified facilitators included holding clinical care sessions, use of standardised care plan and an interface terminology, the nurse's expertise and willingness to individualise.ConclusionThe individualisation process of the standardised care plan involves multiple barriers and facilitators, which influence its degree of accuracy.Relevance to clinical practiceImplementing strategies at an organisational level, professional level and individual level to improve the way the process is carried out would encourage individualising the standardised care plan in a manner that is consistent with the needs of the patient and family; it would improve the quality of care and patient satisfaction.
Seascape genetics of the stalked kelp Pterygophora californica and comparative population genetics in the Santa Barbara Channel
Authors: Hargarten Heidi L. , Johansson Mattias L. , Reed Daniel C. , Coelho Nelson C. , Siegel David A. , Alberto Filipe 
Published: September 2019

We conducted a population genetic analysis of the stalked kelp, Pterygophora californica, in the Santa Barbara Channel, California, USA. The results were compared with previous work on the genetic differentiation of giant kelp, Macrocystis pyrifera, in the same region. These two sympatric kelps not only share many life history and dispersal characteristics but also differ in that dislodged P. californica does not produce floating rafts with buoyant fertile sporophytes, commonly observed for M. pyrifera. We used a comparative population genetic approach with these two species to test the hypothesis that the ability to produce floating rafts increases the genetic connectivity among kelp patches in the Santa Barbara Channel. We quantified the association of habitat continuity and oceanographic distance with the genetic differentiation observed in stalked kelp, like previously conducted for giant kelp. We compared both overall (across all patches) and pairwise (between patches) genetic differentiation. We found that oceanographic transit time, habitat continuity, and geographic distance were all associated with genetic connectivity in P. californica, supporting similar previous findings for M. pyrifera. Controlling for differences in heterozygosity between kelp species using Jost's DEST, we showed that global differentiation and pairwise differentiation were similar among patches between the two kelp species, indicating that they have similar dispersal capabilities despite their differences in rafting ability. These results suggest that rafting sporophytes do not play a significant role in effective dispersal of M. pyrifera at ecologically relevant spatial and temporal scales.
The Impact of a Modified Initial Teacher Education on Challenging Trainees' Understanding of Neuromyths
Authors: McMahon Kendra , Yeh Chloe Shu‐Hua , Etchells Peter J. 
Published: September 2019

ABSTRACTInitial teacher education (ITE) offers an underutilized opportunity for bridging the gap between neuroscience research and educational practice. This article reports on innovations embedded within an ITE program to support trainee teachers to recognize and challenge the persistence of neuromyths. Education researchers, neuroscientists, and psychologists collaboratively applied design‐based research to create, improve, and reflect on original neuroeducational teaching/learning resources for university‐based primary (elementary) ITE trainees. Encouragingly, pre and postsurveys showed reductions in trainees' beliefs in neuromyths and a shift to responses showing uncertainty that suggested their beliefs became unsettled. The most persistent neuromyths were those regarding fish oils, left brain/right brain, and learning styles/visual, auditory, or kinaesthetic (VAK). Trainees retained their initial interest in knowledge about the brain and education, gained confidence, and became more critical about applying the learning sciences in educational contexts.
Fusaric acid instigates the invasion of banana by Fusarium oxysporum f. sp. cubense TR4
Authors: Liu Siwen , Li Jian , Zhang Yong , Liu Na , Viljoen Altus , Mostert Diane , Zuo Cunwu , Hu Chunhua , Bi Fangcheng , Gao Huijun , Sheng Ou , Deng Guiming , Yang Qiaosong , Dong Tao , Dou Tongxin , Yi Ganjun , Ma Li‐Jun , Li Chunyu 
Published: September 2019

Summary

Fusaric acid (FSA) is a phytotoxin produced by several Fusarium species and has been associated with plant disease development, although its role is still not well understood.

Mutation of key genes in the FSA biosynthetic gene (FUB) cluster in Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4) reduced the FSA production, and resulted in decreased disease symptoms and reduced fungal biomass in the host banana plants.

When pretreated with FSA, both banana leaves and pseudostems exhibited increased sensitivity to Foc TR4 invasion. Banana embryogenic cell suspensions (ECSs) treated with FSA exhibited a lower rate of O2 uptake, loss of mitochondrial membrane potential, increased reactive oxygen species (ROS) accumulation, and greater nuclear condensation and cell death. Consistently, transcriptomic analysis of FSA‐treated ECSs showed that FSA may induce plant cell death through regulating the expression of genes involved in mitochondrial functions.

The results herein demonstrated that the FSA from Foc TR4 functions as a positive virulence factor and acts at the early stage of the disease development before the appearance of the fungal hyphae in the infected tissues.
Photoexcited CRY1 and phyB interact directly with ARF6 and ARF8 to regulate their DNA‐binding activity and auxin‐induced hypocotyl elongation in Arabidopsis
Authors: Mao Zhilei , He Shengbo , Xu Feng , Wei Xuxu , Jiang Lu , Liu Yao , Wang Wenxiu , Li Ting , Xu Pengbo , Du Shasha , Li Ling , Lian Hongli , Guo Tongtong , Yang Hong‐Quan 
Published: September 2019

Summary

Arabidopsis CRY1 and phyB are the primary blue and red light photoreceptors mediating blue and red light inhibition of hypocotyl elongation, respectively. Auxin is a pivotal phytohormone involved in promoting hypocotyl elongation. CRY1 and phyB interact with and stabilize auxin/indole acetic acid proteins (Aux/IAAs) to inhibit auxin signaling. The present study investigated whether photoreceptors might interact directly with Auxin Response Factors (ARFs) to regulate auxin signaling.

Protein–protein interaction studies demonstrated that CRY1 and phyB interact physically with ARF6 and ARF8 through their N‐terminal domains in a blue and red light‐dependent manner, respectively. Moreover, the N‐terminal DNA‐binding domain of ARF6 and ARF8 is involved in mediating their interactions with CRY1.

Genetic studies showed that ARF6 and ARF8 act partially downstream from CRY1 and PHYB to regulate hypocotyl elongation under blue and red light, respectively. Chromatin immunoprecipitation‐PCR assays demonstrated that CRY1 and phyB mediate blue and red light repression of the DNA‐binding activity of ARF6 and ARF6‐target gene expression, respectively.

Altogether, the results herein suggest that the direct repression of auxin‐responsive gene expression mediated by the interactions of CRY1 and phyB with ARFs constitutes a new layer of the regulatory mechanisms by which light inhibits auxin‐induced hypocotyl elongation.
Three‐dimensional comparison of the skeletal and dentoalveolar effects of the Herbst and Pendulum appliances followed by fixed appliances: A CBCT study
Authors: Taylor Kyle L. , Evangelista Karine , Muniz Luciana , Ruellas Antônio Carlos de Oliveira , Valladares‐Neto José , McNamara James , Franchi Lorenzo , Kim‐Berman Hera , Cevidanes Lucia Helena Soares 
Published: September 2019

AbstractObjectivesTo compare three‐dimensional (3D) skeletal and dentoalveolar effects of the Herbst and Pendulum appliances followed by fixed orthodontic treatment in growing patients.Setting and sample populationA sample of 35 adolescents with cone‐beam computed tomography scans obtained prior to Herbst and Pendulum treatment (T1) and immediately after fixed appliance treatment (T2).Materials and MethodsPatients with Class II malocclusion was assessed retrospectively and divided into two treatment groups: Herbst group (n = 17, age: 12.0 ± 1.6 years) and Pendulum group (n = 18, age: 12.1 ± 1.5 years), with a mean treatment duration of 2.8 ± 0.8 years and 2.5 ± 0.7 years, respectively. Reconstructions of the maxillomandibular and dentoalveolar regions and data in 3D were obtained relative to cranial base, maxillary and mandibular regional superimpositions. Treatment outcomes (T2‐T1) were compared between both groups using t tests for independent samples (P<.05).ResultsSignificant increase in mandibular length was observed in the Herbst group (7.3 ± 3.5 mm) relative to the Pendulum group (4.6 ± 4.5 mm). Inferior and anterior displacements of Pogonion were 2.2 mm and 1.6 mm greater in the Herbst group, respectively. The mesial displacement of the lower first molars was significantly greater in the Herbst group (1.9 mm). The upper first molars had contrasting results in sagittal displacement, with 0.6 ± 1.7 mm of distal displacement with the Pendulum and 1.4 ± 2.1 mm of mesial displacement with the Herbst. Lower incisor projection and proclination were similar between groups.ConclusionsThe Herbst and Pendulum appliances followed by comprehensive orthodontic treatment effectively corrected Class II malocclusion in growing patients, but with differing skeletal and dentoalveolar effects.
Saliva microbiome in primary Sjögren’s syndrome reveals distinct set of disease‐associated microbes
Authors: Sharma Disha , Sandhya Pulukool , Vellarikkal Shamsudheen Karuthedath , Surin Ajit Kumar , Jayarajan Rijith , Verma Ankit , Kumar Anoop , Ravi Rowmika , Danda Debashish , Sivasubbu Sridhar , Scaria Vinod 
Published: September 2019

AbstractObjectiveThis study systematically aims to evaluate the salivary microbiome in patients with primary Sjögren's syndrome (pSS) using 16S rRNA sequencing approach.MethodsDNA isolation and 16S rRNA sequencing was performed on saliva of 37 pSS and 35 control (CC) samples on HiSeq 2500 platform. 16S rRNA sequence analysis was performed independently using two popular computational pipelines, QIIME and less operational taxonomic units scripts (LoTuS).ResultsThere were no significant changes in the alpha diversity between saliva of patients and controls. However, four genera including Bifidobacterium, Lactobacillus, Dialister and Leptotrichia were found to be differential between the two sets, and common between both QIIME and LoTuS analysis pipelines (Fold change of 2 and p < .05). Bifidobacterium, Dialister and Lactobacillus were found to be enriched, while Leptotrichia was significantly depleted in pSS compared to the controls. Exploration of microbial diversity measures (Chao1, observed species and Shannon index) revealed a significant increase in the diversity in patients with renal tubular acidosis. An opposite trend was noted, with depletion of diversity in patients with steroids.ConclusionOur analysis suggests that while no significant changes in the diversity of the salivary microbiome could be observed in Sjögren's syndrome compared to the controls, a set of four genera were significantly and consistently differential in the saliva of patients with pSS. Additionally, a difference in alpha diversity in patients with renal tubular acidosis and those on steroids was observed.
Root coverage using a dual layer type I non‐cross‐link collagen haemostatic biomaterial – a 10 year follow‐up
Authors: de Abreu F.A.M. , Zenóbio E.G. 
Published: September 2019

AbstractAesthetics and predictability, such as long‐term function, shape, texture, colour and contour of the tissues are important factors in root coverage procedures. Surgical procedures could be recommended to treat gingival recession; for example, the use of collagen membrane stands out among them. This case report shows the clinical efficiency of a dual layer collagen membrane associated with coronal flap displacement to treat a MILLER class II gingival recession on the mandibular right first premolar. The patient had lack of keratinised tissue, accumulation of bacterial biofilm and exposed dental root, creating aesthetic disharmony. The periodontal parameters of probing depth, clinical attachment loss level, recession and width of the keratinised gingiva on the mid‐buccal site were measured at baseline, 120 days, 5 and 10 years post‐surgery. Complete coverage with high, long term stability was obtained. The present study shows that a dual layer membrane could be considered as an option to treat gingival recessions.
A multidimensional examination of marital conflict and subjective health over 16 years
Authors: Shrout M. Rosie , Brown Randal D. , Orbuch Terri L. , Weigel Daniel J. 
Published: September 2019

AbstractGuided by stress process perspectives, this study conceptualizes marital conflict as a multidimensional stressor to assess how three aspects of conflict—frequency of disagreements, breadth of disagreements, and cumulative disagreements—impact subjective health. Longitudinal data of married couples spanning 16 years (n = 373 couples) were analyzed using multilevel modeling. For husbands, more frequent disagreements than usual within a given year were associated with poorer subjective health. For wives, the greater cumulative effects of disagreements over 16 years were harmful for subjective health. We discuss how gendered self‐representations and relationship power issues help explain the findings. This research demonstrated the importance of examining multiple aspects of marital conflict to reveal that their subjective health consequences function differently for wives and husbands.
Dissonant endings of chord progressions elicit a larger ERAN than ambiguous endings in musicians
Authors: Pagès‐Portabella Carlota , Toro Juan M. 
Published: September 2019

AbstractIn major‐minor tonal music, the hierarchical relationships and patterns of tension/release are essential for its composition and experience. For most listeners, tension leads to an expectation of resolution. Thus, when musical expectations are broken, they are usually perceived as erroneous and elicit specific neural responses such as the early right anterior negativity (ERAN). In the present study, we explored if different degrees of musical violations are processed differently after long‐term musical training in comparison to day‐to‐day exposure. We registered the ERPs elicited by listening to unexpected chords in both musicians and nonmusicians. More specifically, we compared the responses of strong violations by unexpected dissonant endings and mild violations by unexpected but consonant endings (Neapolitan chords). Our results show that, irrespective of training, irregular endings elicited the ERAN. However, the ERAN for dissonant endings was larger in musicians than in nonmusicians. More importantly, we observed a modulation of the neural responses by the degree of violation only in musicians. In this group, the amplitude of the ERAN was larger for strong than for mild violations. These results suggest an early sensitivity of musicians to dissonance, which is processed as less expected than tonal irregularities. We also found that irregular endings elicited a P3 only in musicians. Our study suggests that, even though violations of harmonic expectancies are detected by all listeners, musical training modulates how different violations of the musical context are processed.
The challenge of large litters on the immune system of the sow and the piglets
Authors: Oliviero Claudio , Junnikkala Sami , Peltoniemi Olli 
Published: September 2019

AbstractThe use of hyperprolific sow lines has increased litter size considerably in the last three decades. Nowadays, in some countries litters can reach up to 18–20 piglets being a major challenge for the sow's physiology during pregnancy, parturition and lactation. The increased number of piglets born per litter prolongs sensibly the duration of farrowing, decreases the piglets’ average weight at birth and their vitality, increases the competition for colostrum intake and can affect negatively piglets’ survival. This review aims to describe how large litters can affect the immune system of the sow and the piglets and proposes measures to improve this condition.
Air‐liquid interface cell culture: From airway epithelium to the female reproductive tract
Authors: Chen Shuai , Schoen Jennifer 
Published: September 2019

AbstractThe air‐liquid interface (ALI) approach is primarily used to mimic respiratory tract epithelia in vitro. It is also known to support excellent differentiation of 3D multilayered skin models. To establish an ALI culture, epithelial cells are seeded into compartmentalized culture systems on porous filter supports or gel substrata. After an initial propagation period, the culture medium is removed from the apical side of the epithelium, exposing the cells to the surrounding air. Therefore, nutritive supply to the cells is warranted only by the basolateral cell pole. Under these conditions, the epithelial cells differentiate and regain full baso‐apical polarity. Some types of epithelia even generate in vivo‐like apical fluid or mucus. Interestingly, the ALI culture approach has also been shown to support morphological and functional differentiation of epithelial cells that are not normally exposed to ambient air in vivo. This review aims at giving a brief overview on the characteristics of ALI cultures in general and ALI models of female reproductive tract epithelia in particular. We discuss the applicability of ALI models for the investigation of the early embryonic microenvironment and for its implications in assisted reproductive technologies.
Disability at the intersections
Authors: Shifrer Dara , Frederick Angela 
Published: September 2019

AbstractComplete and accurate understandings of stratification depend on more regular consideration of disability. To build sociologists' recognition of disability as a socially constructed axis of stratification, we first demonstrate the construction of the disability category through classic legitimating processes: moral attributions, biological attributions, separation, and dichotomization. Expanding understandings of basic processes of stratification, we then document the centrality of disability in the social construction of class, race, gender, sexual orientation, and age. Finally, we show various ways disability functions as an axis of stratification in intersection with other key axes of stratification.
The removal of butachlor from soil by wastewater‐derived Rhodopseudomonas marshes
Authors: Wu Pan , Xie Liying , Li Jirong , Yang Weiguang , Han Ziqiao , Wu Xiaozhen , Mo Wentao , Wen Cheng , Gao Yang , Wan Tian , Zhang Ying 
Published: September 2019

AbstractButachlor is a systemic selective pre‐emergent herbicide most commonly used to control grasses and broadleaf weeds. Residual butachlor in soil can have harmful ecotoxological effects and remediation is, therefore, important. Effects of Rhodopseudomonas marshes in wastewater effluent on biorestoration of butachlor in soil were investigated. Over a time period of one day, butachlor induced EthB gene expression to synthesize cytochrome P450 monooxygenase which led to the successful bioremediation of the herbicide. Residual organics in wastewater effluent provided sufficient carbon sources for continued growth of R. marshes beyond one day.
Cytologic identification of fungal arthritis in a Labrador Retriever with disseminated Talaromyces helicus infection
Authors: Whipple Kellie M. , Shmalberg Justin W. , Joyce Ashley C. , Beatty Sarah S. 
Published: September 2019

AbstractAn 8‐year‐old, neutered male Labrador Retriever presented with acute forelimb lameness. Clinical signs progressed over one week. On physical examination, right cubital joint effusion and bilateral axillary lymphadenomegaly were noted, and severe internal lymphadenomegaly was observed ultrasonographically. Granulomatous lymphadenitis with intralesional fungi was noted cytologically, and the dog was ultimately diagnosed with disseminated Talaromyces helicus infection via PCR of a pure isolate. Extensive medical therapy was pursued, and months later, an arthrocentesis was performed due to continued lameness and severe cubital joint effusion. The synovial fluid contained increased numbers of neutrophils, macrophages, and multinucleated giant cells. Frequent fungal hyphae were found both intracellularly and extracellularly. These basophilic organisms were 2‐4 µm in width with internal eosinophilic granules, roughly parallel walls, and occasional to frequent septa. Round to oval yeast‐like forms with thin, clear halos were also occasionally identified. Due to the severity of clinical signs, the right thoracic limb was amputated. Histologic examination of the cubital joint revealed marked granulomatous synovitis, fasciitis, panniculitis, and osteomyelitis, all with intralesional fungi. Talaromyces helicus is a very rare cause of disease, reported only in one other dog. Granulomatous lymphadenitis appears to be a feature of this disease, but this report is the first to describe a significant synovial component.