bluuebunny/crossref_metadata_2025_split huggingface dataset:
Techno‐economic Analysis of a Stand‐alone Hybrid Wind/Fuel Cell Microgrid System: A Case Study in Kouhin Region in Qazvin
Authors: Amirkhalili S. A. , Zahedi A. R. 
Published: June 2018

AbstractThe decrease of fossil energy resources and the increasing amount greenhouse gas necessitate the needs of clean sources of energy. One renewable energy source is wind power which has been developing in recent years. Unfortunately, it can happen that no wind power is available during peak hours. In this case, a storage system, charged with backup power, is required. In this study, a hybrid system is presented for a wind farm to provide a reliable power supply and offer, in addition, valuable by‐products. The presented hybrid system consists of four main components: a wind turbine, an electrolyzer, a hydrogen storage tank and a fuel cell. In this paper, the case study for the system was done in Kouhin area of Qazvin province. The technical and economic optimization of the system suggested that in the best scenario (consisting of 3 wind turbines), the annual energy production of the hybrid system would be 2,268,072 kWh, with 9.41% provided by the fuel cell. The results show that the hybrid system would lead to a 10.8% increase in wind power capacity factor. The calculated energy costs and the net present cost for the optimum hybrid system are 0.7599 cent per kilowatt‐hour and 5,235,066 USD.
Nafion/IL Intermediate Temperature Proton Exchange Membranes Improved by Mesoporous Hollow Silica Spheres
Authors: Zhang Y. , Xue R. , Zhong Y. , Jiang F. , Hu M. , Yu Q. 
Published: June 2018

AbstractA novel polyelectrolyte composite membrane was designed and prepared for intermediate temperature proton exchange membrane fuel cells (PEMFCs). It was composed of perfluorosulfonic acid resin (Nafion®), protic ionic liquid (IL, [dema][TfO]) and mesoporous hollow silica spheres (MHSi). The morphologies of MHSi and Nafion‐based composite membranes were characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The effect of MHSi on proton conductivity of the composite membranes versus relative humidity (RH) and temperature (100–140 °C) were investigated. The results indicated, that the Nafion/IL/MHSi composite membranes exhibited excellent proton conductivity even under 30% RH or high temperature (above 100 °C). A high proton conductivity (5.41 mS cm−1) of the composite membrane at 30 °C and 30% RH can be observed from the test result, which was five times higher than that of the pristine Nafion. The N‐IL‐12S composite membrane showed an outstanding proton conductivity, as far as 14.7 mS cm−1 under 140 °C and low RH, which was almost two orders higher than that of the pristine Nafion membrane. Moreover, the unique hollow and mesoporous structure of MHSi improved IL retention rate of the membrane evidently. Together with high thermal stability of the composite membrane confirmed by thermogravimetric analysis (TGA), the Nafion/IL composite membrane improved by MHSi is a potential candidate in intermediate temperature PEMFC.
Thinner retinal layers are associated with changes in the visual pathway: A population‐based study
Authors: Mutlu Unal , Ikram Mohammad K. , Roshchupkin Gennady V. , Bonnemaijer Pieter W. M. , Colijn Johanna M. , Vingerling Johannes R. , Niessen Wiro J. , Ikram Mohammad A. , Klaver Caroline C. W. , Vernooij Meike W. 
Published: June 2018

AbstractIncreasing evidence shows that thinner retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL), assessed on optical coherence tomography (OCT), are reflecting global brain atrophy. Yet, little is known on the relation of these layers with specific brain regions. Using voxel‐based analysis, we aimed to unravel specific brain regions associated with these retinal layers. We included 2,235 persons (mean age: 67.3 years, 55% women) from the Rotterdam Study (2007–2012) who had gradable retinal OCT images and brain magnetic resonance imaging (MRI) scans, including diffusion tensor (DT) imaging. Thicknesses of peripapillary RNFL and perimacular GCL were measured using an automated segmentation algorithm. Voxel‐based morphometry protocols were applied to process DT‐MRI data. We investigated the association between retinal layer thickness with voxel‐wise gray matter density and white matter microstructure by performing linear regression models. We found that thinner RNFL and GCL were associated with lower gray matter density in the visual cortex, and with lower fractional anisotropy and higher mean diffusivity in white matter tracts that are part of the optic radiation. Furthermore, thinner GCL was associated with lower gray matter density of the thalamus. Thinner RNFL and GCL are associated with gray and white matter changes in the visual pathway suggesting that retinal thinning on OCT may be specifically associated with changes in the visual pathway rather than with changes in the global brain. These findings may serve as a basis for understanding visual symptoms in elderly patients, patients with Alzheimer's disease, or patients with posterior cortical atrophy.
Effect of statin use on oncologic outcomes in head and neck squamous cell carcinoma
Authors: Lebo Nicole L. , Griffiths Rebecca , Hall Stephen , Dimitroulakos Jim , Johnson‐Obaseki Stephanie 
Published: June 2018

AbstractBackgroundPreclinical and early‐phase clinical studies have suggested an oncoprotective role of statins in head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to determine whether incidental statin use in patients with human papillomavirus (HPV)‐negative HNSCC is predictive of improved oncologic outcomes.MethodsA retrospective cohort study of 1194 patients from the Ontario Cancer Registry diagnosed with HNSCC from 2007 to 2012 was performed using linked databases from the Institute for Clinical Evaluative Sciences. Overall survival (OS) and disease‐specific survival (DSS) were compared between patients taking statins and controls.ResultsPatients with statin exposure demonstrated improved OS (hazard ratio [HR] 0.758; P = .0011; 95% confidence interval [CI] 0.642‐0.896), and DSS (HR 0.693; P = .0040; 95% CI 0.539‐0.889) compared with those not on statins at the time of diagnosis.ConclusionIncidental statin use at the time of diagnosis of HPV‐negative squamous cell carcinoma (SCC) of the larynx, hypopharynx, and nasopharynx demonstrated improved OS and DSS.
Visualization of nerve fibers around the carotid bifurcation with use of a 9.4 Tesla microscopic magnetic resonance diffusion tensor imaging with tractography
Authors: Saito Shin , Ozawa Hiroyuki , Fujioka Masato , Hikishima Keigo , Hata Junichi , Kurihara Sho , Okano Hirotaka James , Ogawa Kaoru 
Published: June 2018

AbstractBackgroundPrecise imaging of nerves have been challenging in the head and neck region, mainly due to low spatial resolution. Here, we investigated how nerves in the head and neck region could be visualized using an ultra‐high magnetic field MR system.MethodsWe used formol‐carbol‐fixed human cadaveric necks and obtained MR diffusion tensor images (DTIs) using a 9.4 Tesla (T) ultra‐high magnetic field MR system. Afterward, we prepared tissue sections and checked the anatomic relationships between the neurons and the carotid artery in order to confirm that the visualized fibers are indeed neuron fibers.ResultsWe were able to identify nerves, including the vagus nerve, the hypoglossal nerve, and the spinal‐accessory nerve. Hematoxylin‐eosin stained histological sections confirmed neuron fibers in the same anatomic position.ConclusionThis technique has the feasibility to be applied for a more accurate anatomic understanding, maybe even close to a histological level.
Association of E‐cadherin methylation with risk of nasopharyngeal cancer: A meta‐analysis
Authors: Wu Cheng , Peng Shan , Sun Wei , Luo Min , Su Beibei , Liu Dongbo , Hu Guoqing 
Published: June 2018

AbstractBackgroundVarious studies have assessed the association between E‐cadherin methylation and risk of nasopharyngeal cancer (NPC) but the conclusion remains unclear. This meta‐analysis was conducted to evaluate the effects of E‐cadherin methylation on the incidence and clinicopathological characteristics of NPC.MethodsTen studies published up to June 30, 2016, were collected. Odds ratios (ORs) with corresponding confidence intervals (CIs) were calculated and summarized, respectively.ResultsThe E‐cadherin methylation in NPC was significantly higher than those in normal groups (OR 16.23; 95% CI 8.34‐31.60; P < .001). Ethnicity‐stratified analysis indicated that E‐cadherin methylation was strongly correlated with NPC among both Asians (OR 16.98; 95% CI 8.45‐34.14; P < .001) and North Africans (OR 10.67; 95% CI 1.21‐93.72; P = .033). However, further analysis showed that E‐cadherin methylation was not strongly associated with clinicopathological feathers in patients with NPC.ConclusionThe E‐cadherin methylation is strongly associated with the incidence of NPC, which can serve as an effective biomarker for early detection of NPC.
Transoral robotic‐assisted supracricoid partial laryngectomy with cricohyoidoepiglottopexy: Procedure development and outcomes of initial cases
Authors: Morisod Benoît , Guinchard Anne‐Claude , Gorphe Philippe , Schweizer Valerie , Sandu Kishore , Simon Christian 
Published: June 2018

AbstractBackgroundWe report on the feasibility and functional outcome of transoral robotic (TORS) supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP).MethodsCadaveric studies and functional outcome at 3 years using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC‐QLQ‐H&N35), the Functional Outcome Swallowing Scale (FOSS), the Performance Status Scale for Head and Neck Cancer (PSS‐HN), computerized voice analysis, and videotape recordings. Data were compared with a historical cohort of open CHEPs/cricohyoidopexies (CHPs).ResultsThe EORTC‐QLQ‐H&N35 scores, FOSS scores, and PSS‐HN scores at 3 years of 2 operated patients were 46 and 43, 2 and 1, and 75 of 100 (eating in public) and 100 of 100 (normalcy of diet), respectively. The mean fundamental frequency, jitter, shimmer, noise‐to‐harmonic ratio (NHR), and maximum phonation time (MPT) were 85 HZ and 81 Hz, 8.52% and 6.39%, 28.2% and 13.5%, 0.61 and 0.71, 19 seconds and 15 seconds, respectively.ConclusionFunctional outcome data suggest that the procedure is feasible and safe.
No reference quality evaluation of medical image fusion
Authors: Tang Lu , Tian Chuangeng , Qian Jiansheng , Li Leida 
Published: June 2018

AbstractMedical image fusion (MIF) attracts much attention in clinical use. Many MIF algorithms have been proposed over the past decade. Existing MIF algorithms create different fused image, however, current quality evaluation method is not designed for MIF images. So, we present a no reference quality evaluation of medical image fusion. Firstly, a MIF image database (MIFID) is built, and radiologist ratings are selected to conduct subjective test. Then an objective quality evaluation metric of medical image fusion is proposed via the phase congruency and standard deviation. Image salient features and image information are very important for visual quality of fused image. Based on this consideration, we combine the two existing quality evaluation metrics to assess MIF images. Finally, five comparative study experiments are implemented based on the MIFID. Experimental results reveal that the proposed quality evaluation metric is superior to the existing state‐of‐the‐art metrics, which is more applicable to evaluate MIF images.
DC:0–5: DIAGNOSTIC CLASSIFICATION OF MENTAL HEALTH AND DEVELOPMENTAL DISORDERS OF INFANCY AND EARLY CHILDHOOD
Authors: Klaehn Robert L.P. 
Published: June 2018

ABSTRACTThe significant growth in the clinical literature on early childhood psychopathologysince the publication of the Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood: Zero to Three–Revised (DC:0–3R; ZERO TO THREE) in 2005 necessitated substantial revisions to the manual, which resulted in the publication of the DC:0–5: Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood: Zero to Five (ZERO TO THREE) in 2016. In addition to the decision to extend the early childhood diagnoses to include children through age 5 years, significant revisions were made to many diagnoses, and new diagnostic categories were added such as the Relationship Specific Disorder of Infancy/Early Childhood. Other additions, such as guidance for the development of a Cultural Formulation for the young child and his or her family and the inclusion of functional impairment criteria also contribute to making the DC: 0–5a substantially more comprehensive and robust diagnostic framework than its predecessor.
The limitations and potential adverse effects of the premature ventricular contraction response
Authors: Konishi Hiroki , Fukuzawa Koji , Mori Shumpei , Kiuchi Kunihiko , Hirata Ken‐ichi 
Published: June 2018

AbstractA 69‐year‐old man, who had undergone surgery for mitral and tricuspid regurgitation with the Maze procedure for paroxysmal atrial fibrillation, was admitted with an episode of syncope due to sick sinus syndrome. Three days after implantation of a dual‐chamber pacemaker (Accent MRI™, St. Jude Medical Inc.,), ventricular pacing on T‐wave was recorded multiple times. St. Jude Medical Inc. pacemakers have a unique additional algorithm, called premature ventricular contraction response, related to preventing pacemaker‐mediated tachycardia. This algorithm was determined to be a cause of ventricular pacing on T‐wave. We report the limitations and potential adverse effects of such automated algorithms.
Trapeziometacarpal stabilization through dorsoradial ligament reconstruction: An early post‐surgery in vivo biomechanical analyses
Authors: Kerkhof Faes D. , Vereecke Evie E. , Vanovermeire Olivier , Vanhaecke Jeroen , Vanneste Maarten , Stockmans Filip 
Published: June 2018

ABSTRACTLigament reconstruction can provide pain relief in patients with a painful, unstable, pre‐arthritic trapeziometacarpal (TMC) joint. Imbrication of the dorsoradial ligament (DRL) has been proposed as a minimal invasive stabilization technique. It requires less invasive surgery than an Eaton‐Littler technique and shows promising long‐term clinical outcome. We used dynamic CT to objectively review the effects of the imbrication. Four patients with pain and laxity at the TMC joint, but without radiographic signs of osteoarthritis, were recruited. Dynamic CT scans were made during active thumb abduction‐adduction, flexion‐extension, and two functional grip tasks using a radiolucent jig. Scans of the patients were acquired before and 3 to 6 months after DRL reconstruction. Motion of each bone in the articular chain of the thumb was quantified. In addition, we mapped changes in the contact patterns between the articular facets during the entire thumb motion. After DRL imbrication, we found no overall decrease in MC1 movement in three out of four patients. Furthermore, no increase in TMC joint congruency, defined as proximity area size, was found for three out of four patients. Pre‐ and post‐operative differences in congruency across different tasks were patient‐dependent and relatively small. We demonstrated that, from a biomechanical perspective, there is high variability in post‐operative outcome between patients that undergo identical surgical procedures performed by the same surgeon. A post‐operative decrease in range of motion, increase in joint congruency or decrease in proximity area shift during thumb motion is not omnipresent. © 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:2851–2864, 2018.
Reconstructing diaphyseal tumors using radiated (50 Gy) autogenous tumor bone graft
Authors: Puri Ajay , Byregowda Suman , Gulia Ashish , Patil Vijayraj , Crasto Saniya , Laskar Siddharth 
Published: June 2018

AimsEstablish oncologic safety using 50 Gy to sterilize tumor bearing bone before reimplantation in primary diaphyseal high grade extremity tumors, determine extracorporeal radiotherapy (ECRT) graft survival, and analyze factors that affect union at osteotomy sites.Materials and MethodsSeventy non metastatic patients underwent reconstruction with intercalary ECRT grafts sterilized with 50 Gy. Diagnosis included osteosarcoma (38) and Ewing's sarcoma (32). At last follow‐up—49 patients were alive, 19 had died and 2 were lost to follow up. Survivors had minimum follow up of 3 years (range 39‐127 months).ResultsNinty one percent metaphyseal osteotomies united without additional intervention compared to 71% diaphyseal osteotomies. Additional small plate at diaphyseal osteotomy apparently reduced incidence of non‐union (17% vs 31%) (P = 0.49). Addition of morsellised allograft did not help union. There were seven (10%) local recurrences, all in soft tissue. Seventeen of 69 patients (25%) needed removal of ECRT graft. Five year survival for ECRT graft (removal for all causes) was 79% and 84% (excluding removal for local recurrence).ConclusionsReimplanting sterilized tumor bone using 50 Gy for tumor ablation is an easily applicable, oncologically safe, biological reconstruction option for primary diaphyseal extremity tumors.
Digital soil erodibility mapping by soilscape trending and kriging
Authors: Avalos Fabio Arnaldo Pomar , Silva Marx Leandro Naves , Batista Pedro Velloso Gomes , Pontes Lucas Machado , de Oliveira Marcelo Silva 
Published: June 2018

AbstractSpatial representation of soil erodibility (Universal Soil Loss Equation's [USLE] K factor) is critical for soil conservation and erosion modeling. K factor is directly linked to the soil properties, which have a spatially continuous and soilscape related variability. The objective of this study was to test a methodology to map the spatial distribution of soil erodibility in a 1,200 ha sub‐basin making use of available spatial covariates and field data. The analysis was run for the Posses sub‐basin, in southeast Brazil. The topsoil erodibility was calculated at 85 sampled locations. The spatial prediction of soil erodibility was performed using the scorpan approach, in which the trend term for kriging with external drift (KED) was modeled by soilscape covariates selected by multiple linear regression analysis. The results confirmed that relief data could produce feasible results for digital soil erodibility mapping, especially when combined with geostatistical procedures. A comparison with ordinary kriging showed better error statistics and decreased variance of the estimates for the KED model. This could affect significantly the uncertainty of further USLE applications. The best agreement between KED erodibility values and direct measurements of the K factor was observed for the Red–Yellow Argisol (Red–Yellow Ultisol), which is the dominant soil class in the sub‐basin.
Restoring soil functions by means of cyanobacteria inoculation: Importance of soil conditions and species selection
Authors: Román José Raúl , Roncero‐Ramos Beatriz , Chamizo Sonia , Rodríguez‐Caballero Emilio , Cantón Yolanda 
Published: June 2018

AbstractIn recent years, soil inoculation with cyanobacteria has become one of the most promising biotechnological strategies for restoring soil functionality in degraded drylands because of their critical role in increasing soil fertility and preventing erosion. Nevertheless, in order to fully exploit this biotechnology on a large scale, it must still be shown whether inoculated cyanobacteria are capable of developing in soils with different physicochemical properties, and new candidates adapted to desert conditions must be explored. To evaluate the potential of cyanobacteria for restoring soil functions of degraded dryland soils, in this laboratory study, we analyzed the effect of inoculating three native N‐fixing species (Nostoc commune, Scytonema hyalinum, and Tolypothrix distorta), individually and as a consortium, on soil properties from three different semiarid ecosystems in southeast Spain. The biocrust colonization was monitored by determining chlorophyll a content (the typical surrogate used for biocrust biomass). Other methodologies, such as the analysis of soil spectral response and image classification were also applied for cover estimation of the biocrust. After 3 months, all inoculated soils showed cyanobacteria cover of up to 50%, lower albedo and higher chlorophyll a content. Cyanobacterial inoculation also improved soil functions, as they promoted a significant gain in total organic carbon and total nitrogen in all soils. Among inoculation treatments, Nostoc commune and the mixture of all three species promoted the most cyanobacteria coverage, chlorophyll content, and surface darkening, as well as organic carbon and total nitrogen gains in the soil, highlighting their excellent performance in biocrust development.
What deep‐soil profiles can teach us on deep‐time pH dynamics after land use change?
Authors: Brasseur Boris , Spicher Fabien , Lenoir Jonathan , Gallet‐Moron Emilie , Buridant Jérôme , Horen Hélène 
Published: June 2018

AbstractSoil profiles keep records of the legacies of historical land uses on soil physicochemical properties with deep‐soil (3‐m depth) profiles providing information on centuries‐old dynamics. By combining geohistorical archives on past land uses and management practices together with soil pH data from 19 plots scattered across five study areas in North France, we analyzed the effect of two contrasting historical land‐use change trajectories (afforestation of former arable land vs. cultivation after deforestation) on the acidification and alkalinization dynamics along 3‐m‐depth loessic Luvisols profiles. An analysis of covariance and a generalized additive model were used to test the interaction effect between depth and the two studied chronosequences levels on soil pH. Results show two contrasting alkalinization dynamics for formerly acidic forest soils converted to arable land depending on past management practices. One century of liming practices based on hydrated lime is enough for a complete deprotonation, whereas alkalinization dynamic was much slower (two to four centuries are necessary to neutralize the relictual acidity below 2 m) under liming based on chalk‐blocks supply. Per contra, afforestation of former arable land cultivated and limed during at least 2–4 centuries keep an alkaline ‘memory’ effect over more than a millennium. The acidification process is progressive through time from the surface to deeper soil horizons. This suggests that soil pH profiles can be used to estimate time since afforestation of former arable land. Linking deep‐soil pH profiles with chronosequences is a powerful tool to understand the potential impact of future land‐use change trajectories on soil physicochemical properties.