bluuebunny/crossref_metadata_2025_split huggingface dataset:
Profil Penggunaan Obat Tradisional oleh Konsumen Apotek Karanganyar
Authors: Wahyu Eka Sakti  , Anwar Sodik  , Chondrosuro Miyarso  , Widiastuti Tri Cahyani 
Published: December 2024

Obat tradisional merupakan obat yang berasal dari bahan alam. Pemanfaatan obat tradisional di Indonesia terus meningkat dari tahun ke tahun. Data dari studi pendahuluan yang telah dilakukan di beberapa apotek di Kecamatan Karanganyar menunjukan bahwa Apotek Karanganyar memiliki penjualan obat tradisional paling banyak serta memiliki penyediaan obat tradisional paling lengkap di-Kecamatan Karanganyar. Penelitian ini bertujuan untuk memperoleh gambaran penggunaan obat tradisional oleh konsumen Apotek Karanganyar, Kabupaten Kebumen. Jenis penelitian yang digunakan yaitu penelitian observational yang bersifat deskriptif. Pemilihan responden dilakukan dengan teknik purposive sampling dan jumlah responden pada penelitian ini sebanyak 100 orang. Instrumen yang digunakan adalah kuesioner dengan sembilan pertanyaan. Hasil penelitian menunjukan jenis obat tradisional yang digunakan oleh responden adalah jamu (65%), obat herbal terstandar (28%) dan fitofarmaka (7%). Mayoritas responden menggunakan bentuk obat tradisional cairan yang diminum (40%) dan beralasan memilih obat tradisional karena lebih aman (90%), dan menggunaan obat tradisional didasari oleh keinginan sendiri (73%). Obat tradisional yang digunakan oleh responden adalah buatan pabrik (100%) dan responden merasa menjadi lebih baik setelah mengonsumsi obat tradisional (100%). Penyakit yang sering diatasi dengan menggunakan obat tradisional yaitu batuk (14%) dan ambeien (25%). Obat tradisional yang paling banyak digunakan adalah jamu dengan bentuk sediaan cairan obat dalam. Dari hasil penelitian ini disarankan dilakukan penelitian lebih lanjut mengenai evaluasi rasionalitas penggunaan obat tradisional yang ada di masyarakat.
Profil Pengetahuan Remaja Putri di Surabaya terkait Penggunaan Aromaterapi Lavender sebagai Alternatif Penanganan Nyeri Haid
Authors: Nurulia Rochmah  , Vincentius David , Raisha Pramudya Ningrum  , Vicaksono Ahmad Farhan , Islah Farah  , Cahyani Fitri , Diva Al Haq Wan Wahmuda  , Suryani Erni , Ghina Kautsar Shiddiqah  , Kumala Kevin , Bachmid Savira , Adriana Donita Ghassani , Yuda Ana 
Published: December 2024

Nyeri haid (dismenore) adalah kondisi nyeri perut bagian bawah pada wanita yang sedang mengalami menstruasi. Dismenore umum dialami oleh remaja putri. Karena umumnya prevalensi nyeri ini, pencarian akan terapi alternatif dilakukan, yaitu dengan pemanfaatan aromaterapi yang salah satunya adalah aromaterapi lavender. Penelitian dilakukan untuk mengidentifikasi pengetahuan remaja putri di Kota Surabaya mengenai penggunaan aromaterapi lavender sebagai pereda nyeri haid. Instrumen berupa kuesioner yang memuat 24 pernyataan seputar haid dan pengobatan alternatif aromaterapi lavender. Teknik sampling yang digunakan adalah purposive sampling dengan kriteria inklusi remaja putri berusia 15-20 tahun dan sudah mengalami haid. Penelitian dilakukan di 3 SMA negeri, 3 SMA swasta dan 1 perguruan tinggi dengan jumlah total responden sebanyak 261 orang. Skoring dilakukan dengan memberikan nilai jawaban benar=1 dan salah=0. Responden dengan skor >12 (>50%) dikategorikan berpengetahuan baik dan skor ≤12 (≤50%) dikategorikan berpengetahuan kurang baik. Skor sebagian responden (88,5%) adalah >12 (baik) namun beberapa responden ini (11,5%) yang kurang mengetahui tentang cara penggunaan dan efek samping dari aromaterapi lavender. Diperlukan edukasi terutama dalam hal aspek keamanan, penggunaan, dan mekanisme kerja aromaterapi sebagai alternatif penanganan nyeri haid pada remaja putri.
Survei Penggunaan Obat Bahan Alam oleh Mahasiswa di Kota Malang
Authors: Afif Eka Rahma Setiyanto  , Ibrahim Yudhistira , Abdullah  , Zahra Nabilah Amalia , Muhammad Ariq Daffa  
Published: December 2024

Obat bahan alam merupakan salah satu metode pengobatan yang telah banyak digunakan sejak dahulu kala dan diwariskan secara turun-temurun. Mahasiswa dapat mewakili gambaran obat bahan alam diwariskan dari generasi ke generasi. Penelitian ini bertujuan mengobservasi obat bahan alam, tujuan konsumsi, dan sumber informasi obat bahan alam yang dikonsumsi mahasiswa di Kota Malang. Data diperoleh dengan menyebarkan kuesioner tervalidasi yang dilakukan pada Maret – Mei 2022 dalam bentuk Google Form yang disebarkan di berbagai platform sosial media. Kuesioner yang disebarkan adalah kuesioner terbuka dengan jumlah tiga pertanyaan, yaitu obat bahan alam yang pernah dikonsumsi, tujuan konsumsi, dan sumber informasi terkait obat bahan alam. Responden adalah 194 mahasiswa aktif berusia minimal 18 tahun yang ada di empat perguruan tinggi di Kota Malang. Hasil survei menunjukkan golongan obat bahan alam yang paling banyak dikonsumsi adalah jamu sebanyak 16 merek (69,6%). Merek obat yang paling banyak dikonsumsi adalah Tolak Angin (48,4%). Tujuan konsumsi obat bahan alam dominan untuk pengobatan dan menjaga kesehatan (42,27%). Iklan elektronik (31,9%) menjadi sumber informasi obat bahan alam yang paling banyak disebutkan. Kesimpulan dari penelitian ini adalah obat bahan alam menjadi salah satu pilihan mahasiswa di Kota Malang untuk melakukan swamedikasi.
Cervical cancer prevention and control strategy in Ethiopia: Key informant Clinician’s perspective
Authors: Bogale Agajie Likie , Ali Jemal Haidar , Ressom Habtom W , Sherif Zaki A 
Published: December 2024

Abstract

Background: Cervical cancer is a major public health burden in Ethiopia, ranking second among women and disproportionately affecting HIV-positive individuals. In 2020, an estimated 7,445 new cases and 5,338 deaths occurred. Thus, accurate diagnosis, treatment, and palliative care can reduce mortality and improve quality of life, necessitating exploration of challenges and gaps in prevention and control strategies from frontline expert clinicians’ perspectives.
Methods: A qualitative study design using a descriptive phenomenology strategy was employed to collect data from eight experienced clinicians selected purposively from eight governmental hospitals with a large client flow of HIV patients rendering cervical cancer screening services between September and October 2021 in Ethiopia. Semi-structured pre-tested interview guides or probing questions were used to interview the key informants. The interviews took 45 minutes on average. The collected data was then organized, coded, and analyzed thematically.
Results: Key findings highlighted the implementation of health education, provider training, as primary prevention and screening using visual inspection with acetic acid (VIA) and cryotherapy as secondary prevention strategies. Challenges included lack of awareness among women (both HIV positives and negatives), staff burnout, inconsistent screening algorithms, and difficulties in follow-up of positive cases. Recommendations emphasized strengthening awareness through multi-modal approaches, assigning dedicated screening staff, expanding screening access, improving follow-up systems, and addressing socio-cultural barriers. Self-sampling was perceived favorably to increase screening uptake by overcoming fears and privacy concerns, though quality assurance was noted as crucial. High loss to follow-up was attributed to the asymptomatic nature of cervical cancer and lack of awareness about its severity.
Conclusion: Findings underscore the need for comprehensive strategies to enhance early detection, treatment access, and community engagement to reduce the substantial cervical cancer burden, particularly among high-risk HIV-positive women.
Integrating Transcriptomics and Genetics to Identify Expression Patterns of RNF144B and FYN as Potential Predictors of Bacterial Meningitis
Authors: Jiang Hexiang , Yu Xibing , Fan Jingyan , Song Houhui , Yang Yang 
Published: December 2024

Abstract

Bacterial meningitis (BM) requires prompt treatment, especially for neonates, the elderly, and immunocompromised individuals. Understanding the immune response is essential, as it precedes clinical symptoms. However, systematic studies have been lacking. This study identifies immune-related genes that could enhance BM diagnosis and treatment. Mendelian randomization, differential gene expression, and co-expression network analyses revealed key genes linked to BM. RNF144B was identified as a risk gene, correlating with increased neutrophil levels during the initial phase of meningitis, whereas FYN was identified as a protective gene, correlating with increased NKT cells during remission and recovery. Single-cell RNA sequencing and gene set enrichment analyses showed RNF144B expression in monocytes and neutrophils, while FYN was associated with NKT cells. During BM onset, there was an increase in neutrophil proportions and a decrease in NKT cell proportions, indicating a negative correlation. In recovery, RNF144B expression and neutrophil levels decreased, while FYN expression and NKT cell levels rose, underscoring the protective role of NKT cells. FYN may regulate T-cell receptor function in NKT cells, reducing BM risk. This study suggests that the expression patterns of these two genes exhibit significant differences at various stages of the disease, thus offering potential biomarkers for aiding in more accurate diagnoses of BM and monitoring disease progression.
Reciprocal-relationship between the development of "Trans Jogja" public transportation and urban spatial structure in Yogyakarta agglomeration
Authors: Ashari Arif , Olivia Raisya A. , Reswari Az-Zahra A. , Brotowiranti Rayung W. , Hadi Bambang S. , Ervin Muhamad 
Published: December 2024

Transportation activities cannot be separated from the spatial structure of a region. Local spatial structure applies to areas characterized by urban-hinterland systems with modest coverage, such as Yogyakarta. In this paper, we evaluate the reciprocal relationship between the development of public transportation "Trans Jogja" and the urban spatial structure in Yogyakarta City and its satellite areas. The data collected are secondary data obtained from documentation and primary data from observation, including Trans Jogja routes and bus stops, location of population activity centers, land use, and population data. Data analysis was conducted using GIS analysis using average nearest neighbor, buffering, and overlay; statistical analysis using simple linear regression; and descriptive analysis. There are two main findings in this study. First, transportation services develop following the characteristics of population activities, as evidenced by the distribution pattern of routes and bus stops that follow the location of activity centers and population density. Second, transportation development also triggers the formation of urban landscapes that tend to exurbanize. In summary, this study offers alternative information that provides new insights into the reciprocal relationship between transportation development and the spatial structure of cities in Indonesia.
Examining the Use of Virtual Reality to Support Mindfulness Skills Practice in Mood and Anxiety Disorders: Mixed Methods Study
Authors: Blackmore Rebecca , Giles Claudia , Tremain Hailey , Kelly Ryan , Foley Fiona , Fletcher Kathryn , Nedeljkovic Maja , Wadley Greg , Seabrook Elizabeth , Thomas Neil 
Published: December 2024

Background
Virtual reality (VR) has been proposed as a technology to support mindfulness practice through promoting increased engagement and presence. The proposed benefits of this technology have been largely unexamined with clinical populations. Further research is required to understand its clinical potential and utility in improving and managing mental health symptoms.

Objective
This study aims to investigate the proximal impacts of a single, brief, VR-supported mindfulness practice for individuals with a mood or anxiety disorder and to understand user experiences, which may affect the acceptability and efficacy of VR mindfulness for this population.

Methods
This mixed methods study recruited 28 participants with a primary diagnosis of major depressive disorder, bipolar disorder, or anxiety disorder. Participants completed a mindfulness practice wearing a VR headset that was presenting an omnidirectional video of a forest scene, which was overlaid with a guided audio voiceover. Before and after the practice, measures were completed assessing state mindfulness (Toronto Mindfulness Scale), affect (Positive and Negative Affect Schedule), and anxiety (State-Trait Anxiety Inventory Y-1; n=27). Semistructured interviews were then held inquiring about the user experience and were analyzed using thematic analysis (n=24).

Results
After completing the VR-supported mindfulness practice, both measures of state mindfulness on the Toronto Mindfulness Scale, mean curiosity and decentering, increased significantly (Cohen d=1.3 and 1.51, respectively; P<.001). Negative affect on the Positive and Negative Affect Schedule (Cohen d=0.62; P=.003) and State-Trait Anxiety Inventory Y-1 state anxiety (Cohen d=0.84; P<.001) significantly reduced. There was no significant change in positive affect (Cohen d=0.29; P=.08). Qualitative analysis of interviews identified 14 themes across 5 primary theme categories. The results suggested that being mindful during the use of the app was experienced as relatively effortless because of the visual and immersive elements. It was also experienced as convenient and safe, including when compared with prior traditional experiences of mindfulness. Participants also identified the uses for VR-supported mindfulness in managing emotions and symptoms of mental illness.

Conclusions
The results provide preliminary evidence that VR-supported mindfulness can improve emotional states and manage mental health symptoms for those with mood or anxiety disorders. It offers some potential clinical applications for those with mood or anxiety disorders for exploration within future research.
Twenty-Five Years of Evolution and Hurdles in Electronic Health Records and Interoperability in Medical Research: Comprehensive Review
Authors: Shen Yun , Yu Jiamin , Zhou Jian , Hu Gang 
Published: December 2024

Background
Electronic health records (EHRs) facilitate the accessibility and sharing of patient data among various health care providers, contributing to more coordinated and efficient care.

Objective
This study aimed to summarize the evolution of secondary use of EHRs and their interoperability in medical research over the past 25 years.

Methods
We conducted an extensive literature search in the PubMed, Scopus, and Web of Science databases using the keywords Electronic health record and Electronic medical record in the title or abstract and Medical research in all fields from 2000 to 2024. Specific terms were applied to different time periods.

Results
The review yielded 2212 studies, all of which were then screened and processed in a structured manner. Of these 2212 studies, 2102 (93.03%) were included in the review analysis, of which 1079 (51.33%) studies were from 2000 to 2009, 582 (27.69%) were from 2010 to 2019, 251 (11.94%) were from 2020 to 2023, and 190 (9.04%) were from 2024.

Conclusions
The evolution of EHRs marks an important milestone in health care’s journey toward integrating technology and medicine. From early documentation practices to the sophisticated use of artificial intelligence and big data analytics today, EHRs have become central to improving patient care, enhancing public health surveillance, and advancing medical research.
Dualisme Kesultanan di Jambi dan Dampaknya Terhadap Perekonomian Abad 17-18
Authors: Khairunnisa Pasaribu Riska , Lestari Inda , Yanti Risda , Al Kautsar Zulfadhli , Damin M. Syahrul , Indah Amalia Pasaribu Putri 
Published: December 2024

Kejatuhan pelabuhan Malaka ketangan Portugis, membuat pusat-pusat perdagangan lama muncul kembali salah satunya adalah Jambi. Pada awal abad ke-17 Jambi hadir sebagai pelabuhan terkaya ke-2 di Sumatera. Atas reputasi Jambi tersebut Voc mulai tertarik untuk mengunjungi Jambi. VOC (Vereenigde Oostindische Compagnie) berhasil berhasil menjalin kontak kerjasama dengan kesultanan Jambi masa kepemimpinan Sultan Abdul Kahar (1615-1643). VOC mendapat izin membuka loji di Muara Kumpeh serta mendapat hak monopoli perdagangan lada di Jambi. VOC mulai menguasai perdagangan di Jambi hingga melakukan intervensi politik di kesultanan Jambi. Adapun tujuan penulisan ini adalah untuk melihat dualisme kepemimpinan yang terjadi di Kesultanan Jambi akibat dari intervensi yang dilakukan Belanda serta dampaknya terhadap perekonomian. Metode yang digunakan dalam tulisan ini ialah metode sejarah. Dimulai dari pengumpulan sumber, kritik sumber, interpretasi dan dituangkan ke dalam bentuk karya tulisan (historiografi). Hasil penelitian ini menunjukkan intervensi yang dilakukan VOC berhasil memecah Kesultanan Jambi menjadi dua yaitu Hulu dan Hilir (1696). VOC berhasil melengserkan kekuasaan yang sebelumnya dan menggantikan sultan yang pro terhadap mereka. Kesuksesan VOC memonopoli perdagangan lada di Jambi serta memanipulasi perekonomian di Kesultanan, yang tanpa disadari hal tersebut membawa Kesultanan Jambi pada kemunduran dan kemerosotan ekonomi bahkan nyaris jatuh miskin.
EDIÇÃO ESPECIAL
Authors: Da Silva Lopes Theóffillo 
Published: December 2024

Com foco nas áreas temáticas estabelecidas na Política Nacional de Extensão Universitária, a EDIÇÃO ESPECIAL: Caminhos Percorridos tem como objetivo rememorar e revalidar as práticas extensionistas realizadas na Universidade Federal da Paraíba ao longo de sua trajetória. Esta edição especial de lançamento da Revista traz trabalhos que já foram publicados em outras revistas de extensão da UFPB e espera-se contribuir para a divulgação do conhecimento e das práticas extensionistas realizadas. Assim como nas premissas e conceitos apresentados pela Revista Sanhauá, espera-se, também, que ela possa abrir afluentes, superar margens, subverter fronteiras e manter um fluxo constante de aprendizagem.
The Effect of Mandatory Audit Firm Rotation on Firm Value: Evidence from Korea
Authors: Lim Youngdeok 
Published: December 2024

ABSTRACT
This study examines the impact of a mandatory audit firm rotation policy on client firm value from the investors’ perspective. This study is conducted in Korea, where this policy was implemented from 2006 to 2010. Firm value is measured as Tobin’s q in the stock market for the years 2000 to 2013. The study analyzes firm valuation in relation to continuing engagement, voluntary audit firm rotation, and mandatory audit firm rotation during the pre-regulation (2000–2005), regulation (2006–2010), and post-regulation (2011–2013) periods. The findings reveal that investors reacted negatively to client firms being subjected to mandatory audit firm rotation and responded positively once mandatory audit firm rotation was removed. Overall, the results suggest that investors in the financial market are not supportive of mandatory audit firm rotation.
Data Availability: All data are available from the public database identified in the paper.
JEL Classifications: M42.
Assessment of Product Attributes, Consumer Perceived Value, and Repurchase Intention: A Case of All-You-Can-Eat Beef Buffet
Authors: Mujtahidah Anggriani Ummul Muzayyanah  , Wahyu Eka Putri  
Published: December 2024

Products with higher attribute values will create higher consumer value perceptions. The higher the perceived value, the higher the consumer's repurchase intention on the product. This study seeks to analyse the effect of product attributes on the consumer's perceived value and intention to repurchase beef dishes at the All-You-Can-Eat (AYCE) buffet. Unrestricted self-selected surveys were conducted with convenience sampling is utilized, and the number of samples obtained is 230 respondents. Structural Equation Modelling (SEM) analysis was used to investigate the effect of the variables. This study reveals that respondents are predominantly female (66.10%) in the range of 18 to 25 years old, and have visited AYCE to buy beef dishes at least one time. The higher the product attributes value, the higher the consumer's perceived value of beef dishes at AYCE buffet (p <0.05). Regarding the intention to repurchase, this study indicated that perceived value and product attributes have a significant positive effect (p <0.05) on consumers' intention to repurchase beef dishes at AYCE buffet. This research highlights the both intrinsic and extrinsic product attributes bring high perceived value and consumer repurchase intentions. The findings of this study recommend marketers for developing effective marketing strategies through adding value to consumers. Differentiation products and making the decision on intrinsic and extrinsic attributes. To compete with similar businesses, product attributes need to be upgraded and given careful consideration.
Organoleptic Test Of Whole Wheat Flour For Quality Wingko Babat
Authors: Tanpili Harum Caisar , Andriani Cici , Fridayati Lucy , Indrayeni Wiwik 
Published: December 2024

This research was motivated by the absence of research on the effect of whole wheat flour substitution on the quality of wingko tripe. This research analyzes the impact of entire wheat flour substitution of 20%, 35%, and 50% on the quality of shape, color, aroma, texture, and taste of wingko tripe. This type of research is experimental, namely conducting a direct experiment on the effect of whole wheat flour substitution on the quality of wingko tripe, and was repeated three (3) times. The data type is primary data sourced from 3 expert panelists who filled in the organoleptic test format. The analysis technique used is binominal data analysis which looks at whether there is a significant difference between the treatments and then uses analysis of variance (ANOVA) to analyze the organoleptic test data. The results of the analysis of variance show sig <0.05, which means that HO is rejected and HA is accepted, so there is a significant effect, therefore the Duncan test will be continued. The substitution of whole wheat flour affects the quality of taste (wheat) and the results of the wingko tripe quality test for the best whole wheat flour are found in treatment X3 with a 50% substitution of whole wheat flour.