The Activities of Extraction <i>Litsea </i>sp Leaf Plant Against <i>Candida Albicans</i> and <i>Trichophyton Rubrum</i>
Authors: Randa S. Y. , Hamzah Faizah , Andayaningsih Poniah , Supriyatna - 
Published: April 2018

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table.MsoNormalTable	{mso-style-name:"Table Normal";	mso-tstyle-rowband-size:0;	mso-tstyle-colband-size:0;	mso-style-noshow:yes;	mso-style-priority:99;	mso-style-qformat:yes;	mso-style-parent:"";	mso-padding-alt:0cm 5.4pt 0cm 5.4pt;	mso-para-margin:0cm;	mso-para-margin-bottom:.0001pt;	mso-pagination:widow-orphan;	font-size:11.0pt;	font-family:"Calibri","sans-serif";	mso-ascii-font-family:Calibri;	mso-ascii-theme-font:minor-latin;	mso-fareast-font-family:"Times New Roman";	mso-fareast-theme-font:minor-fareast;	mso-hansi-font-family:Calibri;	mso-hansi-theme-font:minor-latin;	mso-bidi-font-family:"Times New Roman";	mso-bidi-theme-font:minor-bidi;} --> <!--[endif]--> <p class="MsoNormal" style="margin-top: 6pt; text-align: justify;"><span style="font-size: 11pt;" lang="EN-US">A study to investigate the antifungal activity of soxhletion extract and maceration extract of the <em>L<span>itsea</span></em><span> sp </span>leaf </span><span style="font-size: 10pt;" lang="EN-US">plant against <em>Candida albicans</em> and <em>Trichophyton</em> <em>rubrum</em> has been done. <em>Litsea</em> sp plant is used for anti-inflammation. Extraction of <em>Litsea<strong> </strong></em><span>sp</span> leaf was conducted with soxhletation and maceration method using ethanol 70% solvent. The dilution tube method was used for detecting antifungal activity as concentration extract 40%; 30%; 20%; 10%; 5%; 2.5%; 125%; 0.625%; 0.3125%; 0.15625%; 0.078125; 0.0%. The results of this study indicated that soxhletion and maceration extract of <em>Litsea </em><span>sp</span> leaf have antifungal activity against <em>Candida albicans </em>and <em>Trichophyton rubrum</em><strong>.</strong> The minimal inhibiting concentration of soxhletion killing concentration of 5% against <em>Candida albicans</em><span>;<em> </em>wh</span>ereas minimal inhibiting concentration at concentration of 1.25% against <em>Trichophyton rubrum</em>. The minimal inhibiting concentration and minimal killing concentration extract at concentration of 10% against <em>Candida albicans, </em><span>while</span> minimal inhibiting concentration and minimal killing concentration at concentration of 2.5% against <em>Trichophyton rubrum</em>.</span></p>