bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel use of a 3D printed heart model to guide simultaneous percutaneous repair of severe pulmonary regurgitation and right ventricular outflow tract aneurysm
Authors: Jivanji Salim G. M. , Qureshi Shakeel A. , Rosenthal Eric 
Published: April 2019

AbstractWe describe percutaneous repair of severe pulmonary regurgitation and a right ventricular outflow tract pseudoaneurysm in a 19-year-old patient after repair of pulmonary atresia, ventricular septal defect, and major aortopulmonary collaterals. A 3D printed model of his heart was used to simulate percutaneous repair with a closure device in the aneurysm neck and a Venus P-valve in the right ventricular outflow tract. The encouraging findings from the simulation allowed us to plan the complex procedure effectively with a successful outcome and avoidance of surgery.
Altered brain functional networks in Internet gaming disorder: independent component and graph theoretical analysis under a probability discounting task
Authors: Wang Ziliang , Liu Xiaoyue , Hu Yanbo , Zheng Hui , Du Xiaoxia , Dong Guangheng 
Published: April 2019

ObjectivesInternet gaming disorder (IGD) is becoming a matter of concern around the world. However, the neural mechanism underlying IGD remains unclear. The purpose of this paper is to explore the differences between the neuronal network of IGD participants and that of recreational Internet game users (RGU).MethodsImaging and behavioral data were collected from 18 IGD participants and 20 RGU under a probability discounting task. The independent component analysis (ICA) and graph theoretical analysis (GTA) were used to analyze the data.ResultsBehavioral results showed the IGD participants, compared to RGU, prefer risky options to the fixed ones and spent less time in making risky decisions. In imaging results, the ICA analysis revealed that the IGD participants showed stronger functional connectivity (FC) in reward circuits and executive control network, as well as lower FC in anterior salience network (ASN) than RGU; for the GTA results, the IGD participants showed impaired FC in reward circuits and ASN when compared with RGU.ConclusionsThese results suggest that IGD participants were more sensitive to rewards, and they were more impulsive in decision-making as they could not control their impulsivity effectively. This might explain why IGD participants cannot stop their gaming behaviors even when facing severe negative consequences.
Robust stylometric analysis and author attribution based on tones and rimes
Authors: Hou Renkui , Huang Chu-Ren 
Published: April 2019

AbstractIn this article, we propose an innovative and robust approach to stylometric analysis without annotation and leveraging lexical and sub-lexical information. In particular, we propose to leverage the phonological information of tones and rimes in Mandarin Chinese automatically extracted from unannotated texts. The texts from different authors were represented by tones, tone motifs, and word length motifs as well as rimes and rime motifs. Support vector machines and random forests were used to establish the text classification model for authorship attribution. From the results of the experiments, we conclude that the combination of bigrams of rimes, word-final rimes, and segment-final rimes can discriminate the texts from different authors effectively when using random forests to establish the classification model. This robust approach can in principle be applied to other languages with established phonological inventory of onset and rimes.
Collusion in palliative care: an exploratory study with the Collusion Classification Grid
Authors: Stiefel Friedrich , Nakamura Kenji , Ishitani Kunihiko , Bourquin Céline , Saraga Michael 
Published: April 2019

AbstractObjectiveCollusion is a largely unconscious, dynamic bond, which may occur between patients and clinicians, between patients and family members, or between different health professionals. It is widely prevalent in the palliative care setting and provokes intense emotions, unreflective behavior, and negative impact on care. However, research on collusion is limited due to a lack of conceptual clarity and robust instruments to investigate this complex phenomenon. We have therefore developed the Collusion Classification Grid (CCG), which we aimed to evaluate with regard to its potential utility to analyze instances of collusion, be it for the purpose of supervision in the clinical setting or research.MethodSituations of difficult interactions with patients with advanced disease (N = 10), presented by clinicians in supervision with a liaison psychiatrist were retrospectively analyzed by means of the CCG.Result1) All items constituting the grid were mobilized at least once; 2) one new item had to be added; and 3) the CCG identified different types of collusion.Significance of resultsThis case series of collusions assessed with the CCG is a first step before the investigation of larger samples with the CCG. Such studies could search and identify setting-dependent and recurrent types of collusions, and patterns emerging between the items of the CCG. A better grasp of collusion could ultimately lead to a better understanding of the impact of collusion on the patient encounter and clinical decision-making.
Substance misuse and parenting: making drugs and gender in the family court
Authors: Flacks Simon 
Published: April 2019

AbstractChildren tend to be represented as the quintessential victims of the ‘drug problem’, with drug-using parents, particularly mothers, characterised as vectors of the risks posed. Although evidence of drug use is not per se an impediment to retaining care of, or contact with, children (per Lady Hale inRe B[2013] UKSC 33, at para. 143), it does pose one of the greatest challenges to social and political norms about ‘good parenting’, and often has a powerful impact on decisions about care within UK family courts. While there is a considerable body of scholarship assessing criminal justice responses to drug use, there has been little research into how the family serves as an important site for the constitution of drug harms and the making of ‘drugs’ and ‘addiction’. This paper is informed by qualitative analysis of approximately 150 case reports in which drug use has been cited as relevant in the determination of guardianship/parenting. The purpose will not be to contest the difficult decisions that judges had to make in these cases but, using perspectives rooted in Science and Technology Studies and feminist drug scholarship, to remain attendant to the ontological multiplicity of objects that emerge from attempts to stabilise drug harms in legal narratives.
Cooking with shea butter is associated with lower blood pressure in the Ghanaian population
Authors: Kofi Amegah A. , Brahuah Emmanuel , Stranges Saverio 
Published: April 2019

Abstract. The cardiovascular health benefits of shea butter, an edible off-white or ivory-colored fat native to West Africans has never been investigated. This is in spite of anecdotal evidence, which suggests that shea butter may have medicinal properties and its bioactive constituents lower certain cardiovascular risk markers. We hypothesized that cooking with shea butter would be associated with lower blood pressure (BP) in the Ghanaian population. Data from the 2014 Ghana Demographic and Health Survey, a nationally representative population-based survey was analyzed. A total of 9396 women aged 15-49 years and 4388 men aged 15-59 years selected from 12,831 sampled households were included in the study. Respondents with average systolic BP of ≥140 mmHg or average diastolic BP of ≥90 mmHg were classified as hypertensive. Multivariable linear and logistic regression adjusting for gender, age, area of residence, religion, ethnic group, marital status, education and wealth index was used to establish the association between shea butter consumption and BP. Overall prevalence of hypertension in the population was 15.1%. Shea butter consumption was associated with 2.43 mmHg (95% CI: −3.54, −1.31) and 1.78 mmHg (95% CI: −2.71, −0.86) decrease in systolic BP and diastolic BP, respectively, and 25% (AOR = 0.75, 95% CI: 0.55, 1.04) reduced odds of hypertension, compared to use of vegetable oils. Region of residence appeared to modify the relationship. We found an association of shea butter consumption with lower BP, which provides the rationale for investigation through rigorous study designs to evaluate the benefits of shea butter consumption for prevention of hypertension and improved cardiovascular health.
Ocean‐Scale Interactions From Space
Authors: Klein Patrice , Lapeyre Guillaume , Siegelman Lia , Qiu Bo , Fu Lee‐Lueng , Torres Hector , Su Zhan , Menemenlis Dimitris , Le Gentil Sylvie 
Published: April 2019

Satellite observations of the last two decades have led to a major breakthrough emphasizing the existence of a strongly energetic mesoscale turbulent eddy field in all the oceans. This ocean mesoscale turbulence is characterized by cyclonic and anticyclonic eddies (with a 100‐ to 300‐km size and depth scales of ∼500–1,000 m) that capture approximatively 80% of the total kinetic energy and is now known to significantly impact the large‐scale ocean circulation, the ocean's carbon storage, the air‐sea interactions, and therefore the Earth climate as a whole. However, ocean mesoscale turbulence revealed by satellite observations has properties that differ from those related to classical geostrophic turbulence theories. In the last decade, a large number of theoretical and numerical studies has pointed to submesoscale surface fronts (1–50 km), not resolved by satellite altimeters, as the key suspect explaining these discrepancies. Submesoscale surface fronts have been shown to impact mesoscale eddies and the large‐scale ocean circulation in counterintuitive ways, leading in particular to up‐gradient fluxes. The ocean engine is now known to involve energetic scale interactions, over a much broader range of scales than expected one decade ago, from 1 to 5,000 km. New space observations with higher spatial resolution are however needed to validate and improve these recent theoretical and numerical results.
Thermophysical Properties of the North Polar Residual Cap using Mars Global Surveyor Thermal Emission Spectrometer
Authors: Bapst J. , Byrne S. , Bandfield J. L. , Hayne P. O. 
Published: April 2019

AbstractUsing derived temperatures from thermal‐infrared instruments aboard orbiting spacecraft, we constrain the thermophysical properties, in the upper few meters, of the north polar residual cap of Mars. In line with previous authors we test a homogeneous thermal model (i.e., depth‐independent thermal properties), simulating water ice of varying porosity against observed temperatures. We find that high thermal inertia (>1,000 J m−2 K−1 s 1/2 or <40% porosity) provides the best fit for most of the residual cap. Additionally, we test the observed data against models with depth‐dependent thermal properties. Models tested converge on similar solutions: we find extensive regions of low surface thermal inertia consistent with a porous layer at the surface (>40% porosity) that densifies with depth into a zero‐porosity ice layer at shallow depths (<0.5 m). We interpret this as evidence of recent water ice accumulation. Our results along the edge of the residual cap imply that denser (<40% porosity) ice is present at the surface and coincides with lower albedo. These results suggest that older ice is undergoing exhumation along much of the residual cap margin. The results support recent water ice accumulation having occurred over specific regions, while ablation dominates in others.
A Carbon Flux Assessment Driven by Environmental Factors Over the Tibetan Plateau and Various Permafrost Regions
Authors: Lin Shan , Wang Genxu , Feng Jinming , Dan Li , Sun Xiangyang , Hu Zhaoyong , Chen Xiaopeng , Xiao Xiao 
Published: April 2019

AbstractIn this study, the spatiotemporal changes in net primary production (NPP) and drivers, including climate change, atmospheric CO2 concentration and land use change, over the Tibetan Plateau from 1979 to 2016 were investigated using the version 4.5 of the Community Land Model. Based on high‐resolution atmospheric forcing data, six numerical experiments were designed to assess the relative contribution of different environmental factors on NPP. Our simulation results suggest that NPP over the Tibetan Plateau has increased significantly at a rate of 2.25 Tg C/year2 since 1979. At the plateau scale, changes in precipitation, CO2 concentration, and land use change contributed approximately 63.3%, 16.7%, and 9.5% to the interannual variation of NPP, respectively. Temperature did not exert a significant effect on the trends of NPP, which results from the increasing temperature enhancing the autotrophic respiration (AR) more than the gross primary production. We also divided the alpine grasslands into four types, including alpine meadow of permafrost, alpine steppe of permafrost, alpine meadow of seasonal frost, and alpine steppe of seasonal frost. We found that the increasing rate of NPP in permafrost regions was significantly higher than that in seasonal frost regions. Compared with other factors, precipitation change played a dominant role in the NPP over the four different types of grasslands. Temperature‐induced change on NPP and AR was larger in the alpine meadow regions compared to in the alpine steppe regions. In addition, NPP and AR showed a more remarkable response to temperature change over alpine meadow of permafrost than other regions.
Sensitivity of a Continuum‐Scale Porous Media Heat and Mass Transfer Model to the Spatial‐Discretization Length‐Scale of Applied Atmospheric Forcing Data
Authors: Trautz Andrew C. , Illangasekare Tissa H. , Howington Stacy , Cihan Abdullah 
Published: April 2019

AbstractFundamental process understanding and description of heat, mass, and momentum exchanges across the land‐atmosphere interface in model boundary forcing parameterizations is critical to the simulation of near‐surface soil moisture dynamics (e.g., bare‐soil evaporation). This study explores the sensitivity of a continuum‐scale porous media heat and mass transfer model to the spatial‐discretization length‐scales (i.e., spatial‐resolution) of near‐surface atmospheric data; the goal is to determine how much data are needed to force the model and adequately capture evaporative water losses and subsurface state variable distributions. The requisite atmospheric forcing data were taken from the high‐resolution, precision bare‐soil evaporation experiments of Trautz et al. (2018, https://doi.org/10.1029/2018WR023102). Simulation results demonstrated that shallow subsurface mass and heat transfer dynamics can be adequately captured with forcing data averaged over large length‐scales, or a minimal number of measurements, provided that soil conditions are properly described. The soil moisture spatial distributions were found to be insensitive to horizontal variations in the forcing data. The model failed to capture small‐scale trends observed experimentally; this did not impact the accuracy of total evaporative water loss estimates however. These results indicate that in future physical experimental efforts conducted at 1–10‐m length‐scales, there is no need to focus on the generation of high‐spatial resolution atmospheric measurements—time and effort would be better spent in characterizing soil conditions and properties. Even though a theoretical foundation was not provided to directly extrapolate this work to the field scale, these findings have practical value in designing field data collection strategies.
The Role of the Subtropical Jet in Deficient Winter Precipitation Across the Mid‐Holocene Indus Basin
Authors: Hunt K. M. R. , Turner A. G. 
Published: April 2019

AbstractThe mid‐Holocene (7–5 ka) was a period with an increased seasonal insolation cycle, resulting from decreased insolation during northern hemisphere winter. Here, a set of six CMIP5 models is used to show that the decreased insolation reduced the upper‐tropospheric meridional temperature gradient, producing a weaker subtropical jet with less horizontal shear. These effects work to reduce the baroclinic and barotropic instability available for perturbations to grow, and in consequence, storm‐tracking results show that there are fewer winter storms over India and Pakistan (known as western disturbances). These western disturbances are weaker, resulting in a reduction in winter precipitation of around 15% in the north Indus Basin. Combined with previous work showing greater northwestward extent of the Indian monsoon during the mid‐Holocene, our Global climate models‐derived results are consistent with the Indus Basin changing from a summer‐growing season in the mid‐Holocene to a winter‐growing season in the present day.
Some Properties of the Solar Wind Turbulence at 1 AU Statistically Examined in the Different Types of Solar Wind Plasma
Authors: Borovsky Joseph E. , Denton Michael H. , Smith Charles W. 
Published: April 2019

AbstractA four‐plasma classification scheme is used to categorize the ACE solar wind data set into four types of plasma: (1) coronal‐hole‐origin plasma, (2) streamer‐belt‐origin plasma, (3) sector‐reversal‐region plasma, and (4) ejecta. The statistical properties of the solar wind fluctuations at 1 AU are analyzed for each of the four types of plasma in the years 1998–2008 using ACE magnetic field and plasma measurements. Between the four types of solar wind plasma there are subtle statistical differences in the spectral indices of (a) trace‐B, (b) trace‐v, (c) total energy, (d) magnetic intensity, and (e) plasma number density. Between the four types of plasma there are significant statistical differences (a) in the Elsässer inward and outward spectral indices, (b) in the outward imbalance, (c) in the Alfvénicity, (d) in the normalized vector‐B, vector‐v, magnetic intensity, and number density fluctuation amplitudes, (e) in the population of strong current sheets, (f) in the population of sudden velocity shears, (g) in the anisotropies of magnetic field and velocity fluctuations, and (h) in the parallel‐to‐B magnetic field fluctuation spectral index. It is argued that the four‐plasma categorization scheme is superior to a slow‐versus‐fast categorization for the study of turbulence and fluctuations in the solar wind.
Silicon microcavity arrays with open access and a finesse of half a million
Authors: Wachter Georg , Kuhn Stefan , Minniberger Stefan , Salter Cameron , Asenbaum Peter , Millen James , Schneider Michael , Schalko Johannes , Schmid Ulrich , Felgner André , Hüser Dorothee , Arndt Markus , Trupke Michael 
Published: April 2019

AbstractOptical resonators are essential for fundamental science, applications in sensing and metrology, particle cooling, and quantum information processing. Cavities can significantly enhance interactions between light and matter. For many applications they perform this task best if the mode confinement is tight and the photon lifetime is long. Free access to the mode center is important in the design to admit atoms, molecules, nanoparticles, or solids into the light field. Here, we demonstrate how to machine microcavity arrays of extremely high quality in pristine silicon. Etched to an almost perfect parabolic shape with a surface roughness on the level of 2 Å and coated to a finesse exceeding F = 500,000, these new devices can have lengths below 17 µm, confining the photons to 5 µm waists in a mode volume of 88λ3. Extending the cavity length to 150 µm, on the order of the radius of curvature, in a symmetric mirror configuration yields a waist smaller than 7 µm, with photon lifetimes exceeding 64 ns. Parallelized cleanroom fabrication delivers an entire microcavity array in a single process. Photolithographic precision furthermore yields alignment structures that result in mechanically robust, pre-aligned, symmetric microcavity arrays, representing a light-matter interface with unprecedented performance.
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
Authors: Mohanty Tirthankar , Fisher Jane , Bakochi Anahita , Neumann Ariane , Cardoso José Francisco Pereira , Karlsson Christofer A. Q. , Pavan Chiara , Lundgaard Iben , Nilson Bo , Reinstrup Peter , Bonnevier Johan , Cederberg David , Malmström Johan , Bentzer Peter , Linder Adam 
Published: April 2019

AbstractNeutrophils are crucial mediators of host defense that are recruited to the central nervous system (CNS) in large numbers during acute bacterial meningitis caused by Streptococcus pneumoniae. Neutrophils release neutrophil extracellular traps (NETs) during infections to trap and kill bacteria. Intact NETs are fibrous structures composed of decondensed DNA and neutrophil-derived antimicrobial proteins. Here we show NETs in the cerebrospinal fluid (CSF) of patients with pneumococcal meningitis, and their absence in other forms of meningitis with neutrophil influx into the CSF caused by viruses, Borrelia and subarachnoid hemorrhage. In a rat model of meningitis, a clinical strain of pneumococci induced NET formation in the CSF. Disrupting NETs using DNase I significantly reduces bacterial load, demonstrating that NETs contribute to pneumococcal meningitis pathogenesis in vivo. We conclude that NETs in the CNS reduce bacterial clearance and degrading NETs using DNase I may have significant therapeutic implications.
Multicolor multiscale brain imaging with chromatic multiphoton serial microscopy
Authors: Abdeladim Lamiae , Matho Katherine S. , Clavreul Solène , Mahou Pierre , Sintes Jean-Marc , Solinas Xavier , Arganda-Carreras Ignacio , Turney Stephen G. , Lichtman Jeff W. , Chessel Anatole , Bemelmans Alexis-Pierre , Loulier Karine , Supatto Willy , Livet Jean , Beaurepaire Emmanuel 
Published: April 2019

AbstractLarge-scale microscopy approaches are transforming brain imaging, but currently lack efficient multicolor contrast modalities. We introduce chromatic multiphoton serial (ChroMS) microscopy, a method integrating one‐shot multicolor multiphoton excitation through wavelength mixing and serial block-face image acquisition. This approach provides organ-scale micrometric imaging of spectrally distinct fluorescent proteins and label-free nonlinear signals with constant micrometer-scale resolution and sub-micron channel registration over the entire imaged volume. We demonstrate tridimensional (3D) multicolor imaging over several cubic millimeters as well as brain-wide serial 2D multichannel imaging. We illustrate the strengths of this method through color-based 3D analysis of astrocyte morphology and contacts in the mouse cerebral cortex, tracing of individual pyramidal neurons within densely Brainbow-labeled tissue, and multiplexed whole-brain mapping of axonal projections labeled with spectrally distinct tracers. ChroMS will be an asset for multiscale and system-level studies in neuroscience and beyond.