bluuebunny/crossref_metadata_2025_split huggingface dataset:
Food Insecurity During Pregnancy and Breastfeeding by Low-Income Hispanic Mothers
Authors: Gross Rachel S. , Mendelsohn Alan L. , Arana Mayela M. , Messito Mary Jo 
Published: May 2019

BACKGROUND AND OBJECTIVES:
Pregnancy, infancy, and toddlerhood are sensitive times in which families are particularly vulnerable to household food insecurity and when disparities in child obesity emerge. Understanding obesity-promoting infant-feeding beliefs, styles, and practices in the context of food insecurity could better inform both food insecurity and child obesity prevention interventions and policy guidelines.

METHODS:
We performed purposive sampling of low-income Hispanic mothers (n = 100) with infants in the first 2 years of life, all of whom were participants in a randomized controlled trial of an early child obesity prevention intervention called the Starting Early Program. Bilingual English-Spanish interviewers conducted semistructured qualitative interviews, which were audio recorded, transcribed, and translated. By using the constant comparative method, transcripts were coded through an iterative process of textual analysis until thematic saturation was reached.

RESULTS:
Three key themes emerged: (1) contributors to financial strain included difficulty meeting basic needs, job instability, and high vulnerability specific to pregnancy, infancy, and immigration status; (2) effects on infant feeding included decreased breastfeeding due to perceived poor maternal diet, high stress, and limiting of healthy foods; and (3) coping strategies included both home- and community-level strategies.

CONCLUSIONS:
Stakeholders in programs and policies to prevent poverty-related disparities in child obesity should consider and address the broader context by which food insecurity is associated with contributing beliefs, styles, and practices. Potential strategies include addressing misconceptions about maternal diet and breast milk adequacy, stress management, building social support networks, and connecting to supplemental nutrition assistance programs.
La capilla de Picote
Authors: Vasco Ferreira Pedro 
Published: May 2019

«Deus quer, o homem sonha, a obra nasce», escribió Fernando Pessoa. Y —prosigo yo sus eternas palabras— así se hace Historia.
Tejida con mil hilos de sueño y amor os traigo hoy la historia de un edificio olvidado en el tiempo, perdido más allá de las montañas, que el destino colocó en mi camino y que ahora, orgullosamente, empujo hacia el vuestro. Os hablo de la pequeña capilla de Nuestra Señora de Fátima, construida en el año 1958 en la parroquia de Picote, en Miranda do Douro (Portugal).
Este no es un edificio paradigmático de la arquitectura religiosa portuguesa; no ha influido en generaciones de arquitectos ni fue objeto de estudios y reflexiones. Tampoco fue el resultado de una divagación profunda sobre el tema. Es sólo un pequeño edificio de culto perdido en los confines del mundo rural que la historia dejó escapar en las curvas del tiempo. Pero sigue siendo incomparablemente bello y verdadero hoy, como lo era en el momento en el que fue levantado.
Padre Costantino Ruggeri, cantor de la belleza
Authors: Leoni Luigi 
Published: May 2019

El padre Costantino Ruggeri nació en Adro —localidad italiana próxima al lago de Iseo, en la provincia de Brescia— en 1925, y terminó su laboriosa e intensa vida terrena en 2007. Religioso y artista, supo compatibilizar ambas vocaciones; como él mismo decía, se le había concedido la gracia y la dicha de haber identificado su fe en el arte y su arte en la fe.
Un hermano suyo en religión, el padre Michele Piccirillo, famoso arqueólogo del Studium Biblicum de Jerusalén, ha escrito: «En las preces de Vísperas de la Liturgia de las Horas, los martes de la tercera semana la Iglesia nos invita a rezar así: Señor, te rogamos por los artistas a los que has confiado la misión de revelar el esplendor de tu Rostro; haz que sus obras lleven a la humanidad un mensaje de paz y esperanza».
Y añade: «En ese espíritu creo que deberíamos de agradecer al Señor por todo lo que el padre Costantino ha hecho de bueno y hermoso por la Iglesia y por la Orden Franciscana. Ha sido un artista cristiano y franciscano, con el sagrado fuego de la belleza en su interior. Un cristiano, un sacerdote, vive para embellecer la Iglesia de Dios, viviendo su vida tras la estela de Cristo (...) El padre Costantino ha hecho a la Iglesia más hermosa, viviendo su vida de cristiano y de sacerdote, poniendo a disposición sus dotes de artista, de las que Dios lo ha hecho dueño en abundancia».
Recorramos brevemente las etapas de su vida.
Open Compared with Arthroscopic Biceps Tenodesis
Authors: Hurley Daire J. , Hurley Eoghan T. , Pauzenberger Leo , Lim Fat Daren , Mullett Hannan 
Published: May 2019

Background:
Biceps tenodesis can be performed via an open or arthroscopic approach, and there is currently no consensus over which method is superior. The purpose of this study was to systematically review the cohort studies available in the literature to ascertain if open or arthroscopic techniques for biceps tenodesis result in superior clinical outcomes.

Methods:
A systematic search of articles in MEDLINE, Embase, and the Cochrane Library databases was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Cohort studies comparing the open and arthroscopic techniques for biceps tenodesis were included.

Results:
Seven clinical trials were identified with 598 patients. The mean follow-up was 23.6 months. In all of the included studies, there was no significant difference (p > 0.05) in any of the functional outcome scoring systems used, including, most commonly, the American Shoulder and Elbow Surgeons (ASES) score and the Constant score. Similarly, no study found a significant difference (p > 0.05) in either patient satisfaction or return to sport. However, 2 studies found a slightly higher rate of complications with the arthroscopic technique due to an increased rate of fixation failure in 1 study and stiffness in the other study.

Conclusions:
This study found that both open tenodesis and arthroscopic tenodesis result in excellent clinical outcomes, with no significant differences between either method.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Impairment of visual acuity and retinal morphology following resolved chronic central serous chorioretinopathy
Authors: Gawęcki Maciej , Jaszczuk-Maciejewska Agnieszka , Jurska-Jaśko Anna , Kneba Małgorzata , Grzybowski Andrzej 
Published: May 2019

Abstract
Purpose
Central serous chorioretinopathy(CSCR) is a complex ocular entity that, in its chronic form, can lead to serious visual impairment and morphological damage to the retina.
The aim of the current retrospective study was to evaluate the damage present after long-standing but resolved central serous chorioretinopathy and refer it to healthy individuals. Correlations between measurable factors—for example, duration of the disease, baseline retinal morphological parameters, or patient age and/or their degree of impairment—were also assessed.
Materials and methods
The study group consisted of thirty-two eyes (13 female and 19 male, mean age 49.6 years SD +/- 10.5) with chronic central serous chorioretinopathy ( mean duration 18.9 months SD +/- 15.4) in which complete resolution of subretinal fluid was achieved after subthreshold micropulse laser treatment. Inclusion criterion was a lack of subretinal fluid within the whole area of the central retina scanned by the spectral domain optical coherence tomography. The group was extracted out of 51 cases of chronic CSCR that were treated with that method. They were analyzed according to final best-corrected visual acuity and retinal morphological parameters as measured by spectral optical coherence tomography with angiography option (OCTA). Results were compared with the outcomes of a control group, which consisted of 40 eyes of healthy individuals with full distance visual acuity (0.0 logMAR, 1.0 Snellen) never treated with subthreshold micropulse laser. Statistical analysis included regarding correlation between final visual acuity and final central retinal thickness and retinal and functional parameters prior to treatment.
Results
Final best-corrected visual acuity after chronic central serous chorioretinopathy was 0.23 logMAR (0.6 Snellen) and central retinal thickness was 39.32 µm smaller than in controls. No correlation was found between final visual acuity and retinal thickness and duration of the disease, patient age, and baseline morphological retinal parameters. OCTA scans revealed impaired choriocapillaries flow signal even following resolution of the disease.
Conclusion
Chronic central serous chorioretinopathy is a potentially damaging clinical entity that results in serious visual impairment, retinal thinning, and choroidal flow defects. Further research is needed to determine precisely the timepoint of this damage.
Toward Overcoming Physical Disability in Spinal Cord Injury: A Qualitative inquiry of the Experiences of Injured Individuals and Their Families
Authors: Nikbakht-Nasrabadi Alireza , mmohammadi nooredin , Yazdanshenas Manijeh , Shabany Maryam 
Published: May 2019

Abstract
OBJECTIVES

Spinal cord injury (SCI) is a life-changing experience for the individuals with SCI and their families. This study aimed to investigate physical strategies used for overcoming physical disability in individuals with SCI.

METHODS

In this qualitative study, 17 SCI persons and 13 family caregivers were selected by a purposeful sampling. Settings of the study were Brain and SCI research (BASIR) center of Tehran University of Medical Sciences and Southern Social Welfare Center of Tehran and SCI Association of Tehran, Iran. Data were collected by face-to-face semi-structured interviews, which were continued until data saturation. The gathered data were concurrently analyzed by the content analysis method.

RESULTS

The data analysis revealed one main theme (towards overcoming physical disability) and three sub-themes: 1) physical rehabilitation by various methods; 2) tendency towards the use of alternative medical methods; and 3) making effort for self-reliance.

CONCLUSION

The participants used physiotherapy and occupational therapy as an effective and essential approach offered by the healthcare team. Some individuals with SCI with help of their family had invented simple rehabilitation equipment for help to their physical rehabilitation. However, most participants had referred to different complimentary medicine specialists based on advice friends and relatives and they often had spent a lot of time and money ineffectively. Therefore, they need training and support of the healthcare team as well as social support to achieve physical independence and physical recovery. Further research is suggested to investigate the barriers to achieving physical empowerment in people with SCI in Iran.
Custom selected reference genes outperform pre-defined reference genes in transcriptomic analysis
Authors: Santos Karen Cristine Gonçalves Dos , Desgagné-Penix Isabel , Germain Hugo 
Published: May 2019

Abstract
Background: RNA sequencing allows the measuring of gene expression at a resolution unmet by expression arrays or RT-qPCR. It is however necessary to normalize sequencing data by library size, transcript size and composition, among other factors, before comparing expression levels. The use of internal control genes or spike-ins is advocated in the literature for scaling read counts, but the methods for choosing reference genes are mostly targeted at RT-qPCR studies and require a set of pre-selected candidate controls or pre-selected target genes.
Results: Here, we report an R-based script to select internal control genes based solely on read counts and gene sizes. This novel method first normalizes the read counts to Transcripts per Million (TPM) and then excludes weakly expressed genes using the DAFT script to calculate the cut-off. It then selects as references the genes with lowest TPM covariance. We used this method to pick custom reference genes for the differential expression analysis of three transcriptome sets from transgenic Arabidopsis plants expressing heterologous fungal effector proteins tagged with GFP (using GFP alone as the control). The custom reference genes showed lower covariance and fold change as well as a broader range of expression levels than commonly used reference genes. When analyzed with NormFinder, both typical and custom reference genes were considered suitable internal controls, but the custom selected genes were more stable. geNorm produced a similar result in which most custom selected genes ranked higher (i.e. were more stable) than commonly used reference genes.
Conclusions: The proposed method is innovative, rapid and simple. Since it does not depend on genome annotation, it can be used with any organism, and does not require pre-selected reference candidates or target genes that are not always available.
Genome wide association mapping and candidate gene analysis for hundred seed weight in soybean [ Glycine max (L.) Merrill ]
Authors: Zhao Xue , Dong Hairan , Chang Hong , Zhao Jingyun , Teng Weili , Qiu Lijuan , Li Wenbin , Han Yingpeng 
Published: May 2019

Abstract
Background

The hundred seed weight (HSW) was one of soybean [Glycine max (L.) Merrill] yield components, and was also especially critical for various soybean food types. In this study, a representative sample consisted of 185 accessions, selected from Northeast China, was tested under six tested environments for determination of quantitative trait nucleotide (QTN) of HSW through genome-wide association study (GWAS).

Result

A total of 24,180 single nucleotide polymorphisms (SNPs) with minor allele frequency more than 0.2 and missing data less than 3% were utilized to the estimate linkage disequilibrium (LD) level in the tested association panel. Thirty-four association signals were identified to be associated with HSW via GWAS. Among them, nineteen QTN were the novel and another fifteen QTN were overlapped or located near the genomic regions of known HSW QTL. A total of 237 genes, derived from 31 QTN, located near peak SNP for six tested environments, were considered as candidate genes, such as plant growing regulation, hormone metabolism, cell, RNA, protein metabolism, development, starch accumulation, secondary metabolism, signaling, and TCA, some of which have been found to participant in the regulation of HSW. A total of 106 SNPs from 16 candidate genes were significantly associated with HSW in soybean.

Conclusions

The identified loci with beneficial alleles and the candidate genes might be valuable for the molecular network and MAS of HSW.
Usefulness of a stool to stabilize dental chairs for external chest compression
Authors: Awata Norimasa , Hitosugi Takashi , Miki Yoichiro , Kawakubo Yoshifumi , Yokoyama Takeshi 
Published: May 2019

Abstract
Objectives: Cardiopulmonary resuscitation (CPR) requires immediate start of external chest compression (ECC) and cardioversion as soon as possible. During dental surgery, CPR should be started in the dental chair considering difficulty to move the patient from the dental chair to the floor. However, all types of dental chairs are not stable for ECC.
We previously developed a procedure to stabilize a dental chair by using a stool. ERC guideline 2015 adopted our procedure when cardiac arrest during dental surgery. The objective of this study was to verify the efficacy of a stool as a stabilizer in different types of dental chairs.
Materials and methods: Three health care providers participated in this study, and 8 dental chairs were examined. ECC were performed on a manikin that was laid on the backrest of a dental chair. A stool was placed under the backrest to stabilize the dental chair. The vertical displacement of the backrest by ECC were compared between with and without a stool, and recorded by a camcorder.
Results: In all 8 dental chairs, the method by using a stool significantly reduced the vertical displacements of the backrest by ECC. The reduction ratios were between nearly 39~85%, although it was different by chairs.
Conclusions: Our procedure to stabilize dental chairs by using a stool significantly reduced the displacement of a backrest against ECC in all chairs.
Clinical relevance: Effective ECC could be performed in dental chairs by using a stool when sudden cardiac arrest occurs during dental surgery.
Escherichia Coli O157:H7: Distribution, molecular characterization, antimicrobial resistance patterns and source of contamination of sheep and goat carcasses at an export Abattoir, Mojdo, Ethiopia
Authors: Abreham Solomon , Teklu Akafete , Cox Eric , Tessema Tesfaye Sisay 
Published: May 2019

Abstract
Background: Cattle have been identified as a major reservoir of E. coli O157:H7 for human infection; the ecology of the organism in sheep and goats is less understood. This study was carried out to determine prevalence, source of infection, antibiotic resistance and molecular characterization of Escherichia coli O157: H7 isolated from sheep and goat.
Methods: Systematic random sampling was carried out at Modjo export abattoir, Ethiopia, from November 2012 to April 2013 to collect 408 samples from 72 sheep and 32 goats. Samples collected were skin swabs, fecal samples, intestinal mucosal swabs and the inside and outside part of carcasses as well as carcass in contacts such as workers hands, knife, hook and carcass washing water. Then, samples were processed following standard bacteriological procedures. Non-Sorbitol fermenting colonies were tested on latex agglutination test and the positives are subjected to PCR for detection of attaching and effacing genes (eae) and shiga toxin producing genes (stx 1 and stx 2). All E. coli O157:H7 isolates were checked for their susceptibility pattern towards 15 selected antibiotics.
Results: E. coli O157:H7 were detected in only 20/408 samples (4.9%). Among these 20 positive samples, 70% (14/20), 25% (5/20) and 5% (1/20) were from sheep, goats and knife samples, respectively. No significant associations were found between carcasses and the assumed sources of contaminations. Of all the 20 isolates virulent genes were found in 10 (50%) of them; 3 (15%) with only the eaeA gene and 7(35%) expressing eaeA and stx 2 genes. All the isolates were susceptible to Norfloxacin (NOR) (100%).
Conclusions: The presence of virulent genes shows E. coli O157:H7 is a potential source of human infection in Ethiopia.
RPINaptaBASE: a Database for RNA-Protein Interaction Network Analysis and Aptamer Design
Authors: Torkamanian-Afshar Mahsa , Lanjanian Hossein , Nematzadeh Sajjad , Tabarzad Maryam , Najafi Ali , Kiani Farzad , Masoudi-Nejad Ali 
Published: May 2019

Abstract
Abstract
Background
The RNA-protein interactions play crucial roles in the biological processes. Recent developments to clarify RNA and protein structural features have the urgent need for designing various databases, related to the specificity and the mechanism of the underlying interactions between a protein and an RNA molecule. The majority of these databases have focused on RNAs or proteins macromolecules independently, and they do not have the capability to run integrated queries on the RNA-protein complex. Theses existing databases have a linear query structure. Furthermore, they only focus on interacting (positive) samples and they do not contain non-interacting (negative) samples.
Results
We developed a Database for RNA-Protein Interaction Network Analysis and Aptamer Design (RPINaptaBASE). RPINaptaBASE has a nested query approach that enables users to apply nonlinear query analysis. The query engine module contains a wide range of features related to RNA and protein sequences and secondary structure elements of these macromolecules, which are helpful to generate custom datasets, especially for machine learning approaches. In this version, more than 175 features were calculated and available to users. It provides a web interface with download management services allowing users to generate desired datasets of unique RNA or protein sequences in independent lists. Furthermore; the web service empowers users to create artificial datasets of positive and negative samples from RNA-protein complexes. In order to present negative samples, the idea of distinguishing protein sequences by their clans and families was employed to efficiently generate non-interacting pairs.
Conclusion
This database prepares a user-friendly platform to study RNA-protein interactions. It also provides an important simplified contribution to the oligonucleotide-aptamer design process using machine learning algorithms. RPINaptaBASE is freely available at http://rpinbase.com
Prevalence and clinical impact of Streptococcus pneumoniae nasopharyngeal carriage in solid organ transplant recipients
Authors: Roca-Oporto Cristina , Cebrero-Cangueiro Tania , Gil-Marqués María Luisa , Labrador-Herrera Gema , Smani Younes , González-Roncero Francisco M. , Marín-Gómez Luis Miguel , Pachón Jerónimo , Pachón-Ibáñez Maria Eugenia , Cordero Elisa 
Published: May 2019

Abstract
Background: S. pneumoniae is the leading cause of community-acquired pneumonia in the solid organ transplant recipient (SOTR); nevertheless, the prevalence of colonization and of the colonizing/infecting serotypes has not been studied in this population. In this context, the aim of the present study was to describe the rate, characteristics, and clinical impact of S. pneumoniae nasopharyngeal carriage.
Methods: A prospective observational cohort of Solid Organ Transplant recipients (SOTR) was held at the University Hospital Virgen del Rocío, Seville, Spain with the aim to evaluate the S. pneumoniae colonization and the serotype prevalence in SOTR. Two different pharyngeal swabs samples from 500 patients were included in two different seasonal periods winter and spring/summer. Optochin and bile solubility tests were performed for the isolation of thew strains. Antimicrobial susceptibility studies (MICs, mg/l) of levofloxacin, trimethoprim-sulfamethoxazole, penicillin, amoxicillin, cefotaxime, ceftriaxone, erythromycin, azithromycin and vancomycin for each isolate were determined by E-test strips. Capsular typing was done by sequential multiplex PCR reactions. A multivariate logistic regression analysis of factors potentially associated with pneumococcal nasopharyngeal carriage and disease was performed. Results: Twenty-six (5.6%) and fifteen (3.2%) patients were colonized in winter and spring/summer periods, respectively. Colonized SOT recipients compared to non-colonized patients were more frequently men (79.5% vs. 63.1%, P<0.05) and cohabitated regularly with children (59% vs. 32.2%, P<0.001). The most prevalent serotype in both studied periods was 35B. Forty-five percent of total isolates were included in the pneumococcal vaccine PPV23. Trimethoprim-sulfamethoxazole and macrolides were the less active antibiotics. Three patients had non-bacteremic pneumococcal pneumonia, and two of them died.
Conclusions: Pneumococcal colonization in SOTR is low with the most colonizing serotypes not included in the pneumococcal vaccines.