bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential expression pattern of genes involved in oxygen metabolism in epithelial oviductal cells during primary in vitro culture
Authors: Stefańska Katarzyna , Knap Sandra , Kulus Magdalena , Kocherova Ievgenia , Celichowski Piotr , Jeseta Michal , Machatkova Marie , Bukowska Dorota , Antosik Paweł 
Published: October 2019

Abstract
Oxygen metabolism is crucial in establishing successful pregnancy, since excessive amount of reactive oxygen species (ROS) may exert deleterious effects on the developing embryo. There are several defense mechanisms against oxidative stress in the female reproductive tract, including production of antioxidant enzymes by oviductal epithelial cells (OECs). Undoubtedly, OECs play major part in female fertility and may also serve as an in vitro model of the oviduct. Therefore, the aim of this study was to investigate the expression of genes involved in oxygen metabolism. We have isolated OECs from oviducts of crossbred gilts (n=45) and maintained their in vitro culture for 30 days, collecting their RNA at days 1, 7, 15 and 30. The gene expression was determined with the use of Affymetrix® Porcine Gene 1.1 ST Array Strip. Our results revealed 166 differentially expressed genes belonging to four ontology groups: „cellular response to oxidative stress”, “cellular response to oxygen-containing compound”, “cellular response to oxygen levels” and “cellular response to reactive oxygen species”, most of which are also involved in other major processes in the organism. However, our findings provide a valuable insight into porcine reproductive biology and may be utilized in optimization of assisted reproduction techniques.

Running title: Genes involved in oxygen metabolism in oviductal epithelial cells
Barriers and facilitators to conducting research by early career psychiatrists: a literature review
Authors: Koelkebeck Katja , Stefanovic Maja Pantovic , Frydecka Dorota , Palumbo Claudia , Andlauer Olivier , Riese Florian , Jovanovic Nikolina , Costa Mariana Pinto da 
Published: October 2019

Abstract

Objectives
To understand and identify factors that promote and prevent research participation among early career psychiatrists (ECPs), in order to understand what would encourage more ECPs to pursue a research career.

Methods
We conducted an electronic search of databases (PubMed and the Cochrane library) using the keywords ‘doctors’, ‘trainees’, ‘residents’, ‘physicians’ and ‘psychiatric trainees’ as well as ‘research’ (MeSH) and ‘publishing’ (MeSH). This search was complemented by a secondary hand search.

Results
We identified 524 articles, of which 16 fulfilled inclusion criteria for this review. The main barriers included lack of dedicated time for research, lack of mentoring and lack of funding. The main facilitators were opportunities to receive mentorship and access to research funding.

Conclusions
Action is needed to counteract the lack of ECPs interested in a career in research. Specific programs encouraging ECPs to pursue research careers and having access to mentors could help increase the current numbers of researching clinicians in the field.
Analisis Pengaruh Kredit Ketahanan Pangan dan Energi (KKP-E) Terhadap Pendapatan Petani Ternak di Kabupaten Wonogiri
Authors: Utomo Eko Budi 
Published: October 2019

Penelitaan ini bertujuan untuk menganalisis pengaruh pemberian Kredit Ketahanan Pangan dan Energi (KKP-E) terhadap pendapatan petani ternak di Kabupaten Wonogiri. Metode dasar penelitian adalah metode analisis deskriptif dan pelaksanaannya dengan metode survey. Penelitian dilakukan di Kabupaten Wonogiri. Pengambilan sampel dengan metode simple random sampling. Hasil penelitian menunjukkan bahwa hubungan faktor-faktor dengan pendapatan peternak dinyatakan dalam model fungsi regresi linier berganda yaitu: Y = 15178510.19 + 3713035.14 X1 + 362495.26 X2 + 169794.77 X3 + 315220.14 X4 - 125964.84 X5 - 451.03 X6 - 151.90 X7 + 2183539.09 D1 - 2157838.42 D2 + e. Hasil analisis regresi menunjukkan bahwa jumlah ternak, jumlah anggota keluarga, tingkat pendidikan, pengalaman berternak, umur peternak, biaya pakan, biaya obat, penggunaan kredit, dan penguasaan lahan secara bersama-sama berpengaruh nyata terhadap pendapatan petani ternak. Secara individu faktor jumlah ternak, pengalaman berternak, biaya pakan, biaya obat dan pengguaan kredit berpengaruh nyata terhadap pendapatan petani ternak, sedangkan jumlah anggota keluarga, tigkat pendidikan, umur peternak, dan penguasaan lahan tidak berpengaruh nyata terhadap pendapatan petani ternak.
Apakah Transfer Tunai Pemerintah Memperburuk Modal Sosial? Kasus di Indonesia
Authors: Kharisma Bayu 
Published: October 2019

Tujuan penelitian ini adalah mengevaluasi dampak kebijakan pemerintah dalam bentuk tunai terhadap modal sosial di Indonesia. Metode yang akan digunakan dalam penelitian ini adalah differences-in-differences (DID), sedangkan data yang digunakan adalah Indonesia Familiy Life Survey tahun 2000 dan 2007. Berdasarkan hasil estimasi menunjukkan bahwa rumahtangga penerima bantuan tunai tidak bersyarat yaitu Bantuan Langsung Tunai (BLT) lebih aktif terlibat dalam modal sosial, terutama dalam kegiatan arisan. Salah satu motivasi rumahtangga mengikuti partisipasi kegiatan arisan antara lain adalah untuk memiliki akses kredit dan kemampuan untuk mempertahankan daya beli atau melakukan consumption smoothing pada saat terjadi kenaikan harga bahan bakar minyak (BBM) di Indonesia. Sementara itu, rumahtangga penerima bantuan tunai tidak bersyarat yaitu Program Keluarga Harapan tidak berpengaruh secara statistik terhadap modal sosial di Indonesia. Temuan ini menunjukkan bahwa rumahtangga yang menerima bantuan Program Keluarga Harapan cenderung tidak aktif atau terlibat dalam kegiatan modal sosial di Indonesia.
Digital Storytelling: an Influential Reading Comprehension and Creativity Tool for the 21st Century Literacy Skills
Authors: Aboo Bakar Rofiza 
Published: October 2019

Digital storytelling has been proposed as an influential language learning tool that can facilitate learners’ reading comprehension and creativity. There is an interplay between digital storytelling and comprehension. Likewise, there is a connection between digital storytelling and creativity. However, this chemistry that exists is far more complex than previous studies have expressed. This paper puts forth a novel model by which to honor the inter-relationship among digital storytelling, reading comprehension and creativity. The model proffers a practical aim that can allow teachers to recognize and applaud students’ effort whenever they create their digital storytelling, for comprehension and creativity, among other 21st-century literacy skills, have simultaneously and ideally taken place.
Antioxidants, protein, oil content and fatty acids profiles of chia seeds (Salvia hispanica L.) genotype Tzotzol growing in three tropical ecosystems of Bolivia, Ecuador and Paraguay
Authors: AYERZA Ricardo 
Published: October 2019

Chia is a summer annual of the Lamiaceae. The objective of this study was to
investigate the effect of growing location on the antioxidants content and
composition in one genotype of chia, and the potential relationship with its
major nutritional compounds, as protein, oil, and fatty acids. This study was carried out with black‑spotted
chia seeds commercially grown in three different ecosystems, Tropical Rain
Forest, Sub Humid Chaco, and Campo Cerrado, located in Ecuador, Bolivia and
Paraguay, respectively. Flavonols quercetin, myrcetin, kaempherol, caffeic acid,
chlorogenic acid, and SDG lignan compound presence was detected by
chromatographic analysis. No significant
(P&lt;0.05) differences between seed origins= were found.
Total oil content was significantly (P&lt;0.05) higher in the seeds from
Ecuador (34.2%) than all other locations, followed by the seeds from Bolivia (32.5%)
which was significantly (P&lt;0.05) higher compared to Paraguay (31.6%). The content of α‑linolenic fatty acid in
seeds from Ecuador was significantly (P&lt;0.05) higher compared to the seeds
from all three locations. No significant correlation (P&lt;0.05) between α
-linolenic fatty acid and polyphenols content was detected. The results
indicate that protein content, oil content and fatty acid profile
characteristics of the chia are affected by the different ecological conditions
of the tested ecosystems, which not affect the polyphenols content, and composition.
Heat transfer to water near the critical point: evaluation of the ATHLET thermal-hydraulic system code
Authors: Gschnaidtner T. , Rodrigáñez I. Aymerich , Lerchl G. , Wieland C. , Spliethoff H. 
Published: October 2019

Abstract
The heat transfer coefficient is an essential measure in the predesign of supercritical water-cooled reactors (SCWRs). At supercritical pressures, three distinct heat transfer modes exist: normal, improved, and deteriorated. The heat transfer behavior of supercritical water in the pseudo-critical range is different from that of single-phase fluids in the subcritical range. These heat transfer modes differ from those of single-phase flow at subcritical pressures, resulting in an unusual behavior of the heat transfer coefficients. Moreover, during accidental scenarios, when the operating pressure is reduced from supercritical to subcritical conditions, a boiling crisis may occur. During pressure reduction, temporary phenomena such as superheating of the cladding temperature can endanger the safe operation of SCWRs. In order to analyze operational and accidental scenarios of SCWRs, thermal-hydraulic system codes such as ATHLET are applied. However, the prediction capabilities of thermal-hydraulic system codes rely on a comprehensive validation work based on experimental data. This study presents an extensive analysis of the applicability of ATHLET at the near-critical pressure range. ATHLET is assessed against the LESHP-database and two trans-critical transient experiments. At supercritical pressures, the heat transfer coefficient correlations are evaluated with regard to their prediction accuracy and numerical problems including the “multiple solutions problems”. The trans-critical transient experiments are used to test the prediction capability of ATHLET with respect to transient heat transfer phenomena including critical heat flux, film boiling and return to nucleate boiling.
ATHLET extensions for the simulation of supercritical carbon dioxide driven power cycles
Authors: Hofer M. , Buck M. , Starflinger J. 
Published: October 2019

Abstract
The Fukushima accident reveals the need for additional safety systems for nuclear power plants. One promising option is the supercritical carbon-dioxide (sCO2) heat removal system, which consists of a simple Brayton cycle. This study provides an overview of the extensions and validation of the thermal-hydraulic system code ATHLET for the simulation of sCO2 power cycles, especially with regard to the sCO2 heat removal system. The properties of CO2, heat transfer and pressure drop correlations, as well as compact heat exchanger and turbomachinery modelling are considered.
Economic concept of architectural support of construction of mountain objects
Authors: Balikoev A. A. , Kozyrev O. R. , Salbieva A. Ch. , Odintsov V. A. 
Published: October 2019

The article is devoted to the economic aspect of the architectural support of the development of the mountainous areas of the South of Russia. The effectiveness of the development of territories in mountainous terrain depends on the success of combining the principles of designing objects and the state of the environment, especially in the conditions of unique for recreational opportunities depressed regions, for example, the territory “Tagauria” (North Ossetia – Alania), which can become an object of international tourism. The success of the development of mountain areas for industrial and agricultural production is determined by industrial investment projects. The urgency of the task of forming the natural and technogenic risk of mountain areas and solving urban planning tasks based on comprehensive research, one of the criteria of which is the economic efficiency of the object being created, is shown. The mechanism of influence of innovative technologies developed at mining enterprises on the economics of the use of terrestrial resources is formulated. A model is formulated for determining the ecological and economic effect of developing a mountainous area by integrating both aspects. An indicator of the ecological and economic efficiency of the development of a mountain area is given The necessity of introducing into the practice of calculating the effectiveness of architectural support objective criteria is shown. It is shown that the ecological and economic efficiency of the development of territories depends on the integration of innovative methods with traditional methods.
Formulation of Two-Stage Stochastic Programming with Fixed Recourse
Authors: Ahmed Hashnayne 
Published: October 2019

Stochastic Programming is an asset for the next world researchers due to its uncertainty calculations, which has been skipped in deterministic world experiments as it includes complicated calculations. Two-stage stochastic programming concerns two time period decisions based on some random parameters obtained from past experience or some sort of survey. The objective function for formulating two-stage stochastic programming with fixed recourse includes two parts: first-stage forecast and second-stage fixed decisions based on the experiment results. The constraints are similar to the normal optimization techniques rather some adjustments of requirements and technology assets. The fixed recourse decisions are sort of decisions from the deterministic world. Formulation techniques of two-stage stochastic programming with fixed recourse may be used for further complications arises in stochastic programming like complete recourse problems, multi-stage problems, etc. And that’s why Two-stage stochastic programming with fixed recourse is called the primary model for stochastic programming.
The sexually transmitted diseases in Zaporizhzhia region, features in regional disease at 2012-2017
Authors: Lashkul Z. V. , Balashov D. G. 
Published: October 2019

Purpose of the study. The regional peculiarities of STDs in Ukraine and Zaporizhzhia region at 2012-2017 were study.
Materials and methods. The data of state and industry statistics in Ukraine and Zaporizhzhya region (2012-2017) and also statistical methods of epidemiological analysis and graphic images are used.
Results. For the period under investigation, bothin Ukraine and in Zaporizhzhia region there was a tendency to reduce the incidence o fclassical sexually transmitted diseases, at the sametime; the rewerees tablished regional differences between the indicators of syphilis and gonorrheain Ukraineand Zaporizhzhia region.
Under investigation period, both in Ukraine and in Zaporizhzhia region, there was a tendency to reduce the incidence of classical sexually transmitted diseases; at the same time are established differences between the indicators of morbidity of syphilis and gonorrhea Ukraine and Zaporizhzhia region.
Conclusions. The results require the introduction of changes to regional and state programs on the prevention of sexually transmitted diseases, focusing on age and gender and regional peculiarities of their registration.
Prospective Evaluation of Vacuum-Assisted therapy in patient with abdominal sepsis
Authors: Bilianskyi L. S. , Prystaia Y. V. , Tyshko R. O. , Dubenko Y. M. , Myroshnichenko Y. Y. 
Published: October 2019

Purpose of the study. Improve treatment results of patients with abdominal sepsis, due to the diffuse acute secondary peritonitis, by choosing of the optimal method of laparostomy.
Materials and methods. The analysis of treatment of 35 patients with common secondary peritonitis and abdominal sepsis accompanied by septic shock with score of the Mannheim Peritonitis Index 29, which were treated by laparostomy, during the period from 2014 to 2019, was performed. The patients were divided into 2 groups. The treatment group consists of 17 patients who were treated by negative pressure therapy (NPT) – a technique of vacuum-assisted closure of theabdominalcavity(VAC) withanegativepressure levels from 50 to 125 mm Hg in the continuous or intermittent modes. The control group consists of 18 patients, who were treated by laparostomy with planned abdominal sanations, with intervals between sanations of 24, 36, 48 hours, depending on the degree of development of peritonitis and the condition of the patient (as needed).
Results. The average length of hospital stay in ICU department was 11,3 days in treatment group
(from 5,2 to 16,4 days), compared with the control group 22,9 days (from 3,4 to 47,4 days). The number of relaparotomies during which the replacing or removing of VAC-bandages was performed at the end of NTP was 3,8 (from 1 to 4) in the treatment group and 6,8 (from 3 to 11) in the control group. Adequate source control of abdominal sepsis was achieved in all operated patients of the treatment group, and in the control group only in 7 patients (38,9%). The overall mortality rate in both groups was 20%. In the treatment group, which were treated by applying NTP 2 patients were died (11,8%) while in the control group this count was 27,8% (7 patients).
Conclusion. The experience of applying NTP and VAC-bandages in the complex treatment of abdominal sepsis, with values of the SOFA 3, shows better results in comparison with other methods of open abdomen, reducing the length of stay in the ICU by 2 times, the mortality rate is 3 times and this allows to complete treatment with final closure of the abdominal cavity more than in 50% of patients.
PROGRAMATİK REKLAMCILIK: KAVRAM, İŞLEYİŞ VE POTANSİYELİ AÇISINDAN DEĞERLENDİRMESİ
Authors: ZEREN Deniz , KEŞLİKLİ İsmail 
Published: October 2019

İnternet
milyarlarca insan tarafından, iletişim için, yoğun olarak, tercih edildikçe
dijital pazarlama ve çevrimiçi reklamcılık, işletmelerin pazarlama iletişiminde
kullandıkları en önemli stratejiler haline gelmeye başlamıştır. Programatik
reklamcılık, işletme enformasyon sistemlerinde, yapay zekâ ve veri madenciliği
alanlarında yaşanan gelişmelerin bir yansıması olarak internette gelişimini
sürdüren grafik teknolojilerle büyük veri işlenerek uygulanan güncel bir
pazarlama tekniğidir. Temelde, yayıncılar ve reklam verenler tarafından sunulan
verileri, dijital ticareti platformlarda buluşturarak, tarafların otomatik,
daha hızlı ve çok daha etkili bir şekilde çevrimiçi reklam alım satımı
yapmasına yarayan bir teknolojidir. Geleneksel reklamcılığa yeni boyutlar
kazandıran teknik, gerçek zamanlı veriyi işleyerek, satın alma veya reklama
tıklama anında gerçek zamanlı tüketici ilgisine göre anlık reklam teklifleri
oluşturabilmeye imkân sağlamaktadır. Dolayısıyla bu çalışmanın öncelikli amacı,
işletmelere ve tüketicilerin çevrimiçi deneyimlerine katkı sağlayan bu tekniğin
kavramsal olarak açıklanmasını sağlayarak, henüz başlangıç aşamasındaki yazına
teorik katkı sağlamaktır. Bu amaçla bu çalışmada programatik reklamcılığın
tanım, terim, işleyiş ve temel kavramları işleyiş açısından ve teorik açıdan
incelemiştir. Bu çalışmada programatik reklamcılık reklam verenler açısından,
yayıncılar açısından ve tüketiciler açısından ele alarak değerlendirmektedir. Ayrıca
programatik reklamcılık sürecine, ekosistemine ve henüz başlangıç aşamasında olan
ilgili yazının taranmasına yer verilerek geleceğe yönelik uygulama ve çalışma
düzlemlerine doğru bir adım atılmasına çalışılmaktadır.
Desain Atena Mikrostrip Bentuk Lingkaran Menggunakan Metode Pencatuan Langsung dan Slot Untuk Antena 5G
Authors: Haidi Junas 
Published: October 2019

Paper ini adalah merancang antena mikrostrip bentuk lingkaran dengan menggunakan metode slot untuk aplikasi antena 5G yang bekerja pada frekuensi resonansi 28 GHz. Dari hasil penelitian antena yang didesain didapatkan lebar bandwidth 1,044 GHz, nilai return loss-36,871 dB, VSWR 1,0865, Impedansi 43 Ohm dan HPBW 18,20 dengan pancaran utama 10 dBi. Metode slot yang digunakan dalam perancangan antena pada penelitian ini berfungsi untuk melebarkan bandwidth dan memperkecil nilai return loss antena. Berdasarkan parameter antena yang didapat saat perancangan dan simulasi antena, maka perancangan antena yang dibuat bentuk lingkaran untuk apalikasi 5G pada frekuensi 28 GHz telah memenuhi standar antena. Dengan demikian hasil perancangan yang telah dilakukan telah bisa dibuat atau dipabrikasi untuk digunakan sebagai antena 5G.
Prosedur efektif pengembangan aplikasi basis data
Authors: Hatala Zulkarnaen 
Published: October 2019

Abstract—Efficient and quick procedure to build a web application is presented. The steps are intended to build a database application system with hundreds of tables. The procedure can minimize tasks needed to write code and doing manual programming line by line. The intention also to build rapidly web-based database application. In this method security concerning authentification and authorization already built in ensuring the right and eligible access of the user to the system. The end result is ready to use the web-based 3-tier application. Moreover, the application is still flexible to be customized and to be enhanced to suit more specific requirement in part of each module of the software both the server-side and client-side programming codes. Abstrak—Pada penelitian kali ini diusulkan prosedur cepat dan efisien pengembangan aplikasi basis data menggunakan generator aplikasi. Bertujuan untuk meminimalisir penulisan bahasa pemograman. Keuntungan dari prosedur ini adalah bisa digunakan untuk mengembangkan aplikasi basis data secara cepat terutama dengan sistem basis data yang terdiri dari banyak tabel. Hak akses dan prosedur keamanan standar telah disediakan sehingga setiap user terjamin haknya terhadap entitas tertentu di basis data. Hasil generasi adalah aplikasi basis data berbasis web yang siap pakai. Sistem aplikasi yang terbentuk masih sangat lentur untuk untuk dilakukan penyesuaian setiap komponen aplikasi baik di sisi server maupun di sisi client.