bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chlorate/Fe‐Bearing Phase Mixtures as a Possible Source of Oxygen and Chlorine Detected by the Sample Analysis at Mars Instrument in Gale Crater, Mars
Authors: Hogancamp J. V. , Sutter B. , Morris R. V. , Archer P. D. , Ming D. W. , Rampe E. B. , Mahaffy P. , Navarro‐Gonzalez R. 
Published: September 2018

AbstractOxygen and HCl gas releases detected by the Sample Analysis at Mars (SAM) instrument on board the Mars Science Laboratory Curiosity rover in several Gale Crater samples have been attributed to the thermal decomposition of perchlorates and/or chlorates. Previous experimental studies of perchlorates mixed with Fe‐bearing phases explained some but not all of the evolved oxygen releases and cannot explain the HCl releases. The objective of this paper was to evaluate the oxygen and HCl releases of chlorates and chlorate/Fe phase mixtures in experimental studies and SAM evolved gas analysis data sets. Potassium, magnesium, and sodium chlorate were independently mixed with hematite, magnetite, ferrihydrite, and palagonite and analyzed in a thermal evolved gas analyzer configured to operate similarly to the SAM instrument. Fe phases depressed the chlorate decomposition temperature 3–214 °C and consumed up to 75% of the evolved oxygen from chlorate decomposition. Chlorate/Fe phase mixtures have oxygen and HCl releases consistent with some samples analyzed by SAM. Reported oxychlorine abundances based on calculations using oxygen detected by SAM could be minimum values because Fe phases consume evolved oxygen. The results of this work demonstrate that chlorates could be present in the Martian soil and that oxygen and HCl release temperatures could be used to constrain which chlorate cation species are present in samples analyzed by SAM. Knowledge of which chlorates may be present in Gale Crater creates a better understanding of the detectability of organics by evolved gas analysis, habitability potential, and the chlorine cycle on Mars.
Salt Marsh Loss Affects Tides and the Sediment Budget in Shallow Bays
Authors: Donatelli Carmine , Ganju Neil Kamal , Zhang Xiaohe , Fagherazzi Sergio , Leonardi Nicoletta 
Published: September 2018

AbstractThe current paradigm is that salt marshes and their important ecosystem services are threatened by global climate change; indeed, large marsh losses have been documented worldwide. Morphological changes associated with salt marsh erosion are expected to influence the hydrodynamics and sediment dynamics of coastal systems. Here the influence of salt marsh erosion on the tidal hydrodynamics and sediment storage capability of shallow bays is investigated. Hydrodynamics, sediment transport, and vegetation dynamics are simulated using the numerical framework Coupled Ocean‐Atmosphere‐Wave‐Sediment Transport in the Barnegat Bay‐Little Egg Harbor system, USA. We show that salt marsh erosion influences the propagation of tides into back‐barrier basins, reducing the periodic inundation and sediment delivery to marsh platforms. As salt marshes erode, the sediment trapping potential of marsh platforms decreases exponentially. In this test case, up to 50% of the sediment mass trapped by vegetation is lost once a quarter of the marsh area is eroded. Similarly, without salt marshes the sediment budget of the entire bay significantly declines. Therefore, a positive feedback might be triggered such that as the salt marsh retreats the sediment storage capacity of the system declines, which could in turn further exacerbate marsh degradation.
Introducing Finer Grains Into Bedload: The Transition to a New Equilibrium
Authors: Dudill Ashley , Lafaye de Micheaux Hugo , Frey Philippe , Church Michael 
Published: September 2018

AbstractSimplified experiments on fine grain inputs to a coarse bed in mobile equilibrium were undertaken in a small, steep, narrow flume using spherical glass particles to study the influence upon the channel response of the size ratio between the bed (Dc) and the input fines (Df). Size ratios (Dc/Df) between 7.14 and 1.25 were tested, with a constant flow and coarse sediment feed rate and a variety of fine and total feed rates. Transition to a new, two‐size equilibrium occurs through slope adjustment (aggradation/degradation), accompanying a change in sediment mobility created by the addition of the fine material. Previous work has documented superior mobility following a fine grain input; the present experiments identify limits of this behavior related to the fine grain size, the proportion of fines introduced, and the total sediment supply. The mechanistic reasons for these limits are examined with respect to the grain sorting behavior, leading to the development (or not) of a quasi‐static layer of the fine material at the base of the transport layer. Despite the variation in bed slope response depending upon these factors, the slope transitions consistently follow an exponential profile.
North Atlantic Midlatitude Surface‐Circulation Changes Through the Plio‐Pleistocene Intensification of Northern Hemisphere Glaciation
Authors: Bolton Clara T. , Bailey Ian , Friedrich Oliver , Tachikawa Kazuyo , de Garidel‐Thoron Thibault , Vidal Laurence , Sonzogni Corinne , Marino Gianluca , Rohling Eelco J. , Robinson Marci M. , Ermini Magali , Koch Mirjam , Cooper Matthew J. , Wilson Paul A. 
Published: September 2018

AbstractThe North Atlantic Current (NAC) transports warm salty water to high northern latitudes, with important repercussions for ocean circulation and global climate. A southward displacement of the NAC and Subarctic Front, which separate subpolar and subtropical water masses, is widely suggested for the Last Glacial Maximum (LGM) and may have acted as a positive feedback in glacial expansion at this time. However, the role of the NAC during the intensification of Northern Hemisphere glaciation (iNHG) at ~3.5 to 2.5 Ma is less clear. Here we present new records from Integrated Ocean Drilling Program Site U1313 (41°N) spanning ~2.8–2.4 Ma to trace the influence of Subarctic Front waters above this mid‐latitude site. We reconstruct surface and permanent pycnocline temperatures and seawater δ18O using paired Mg/Ca‐δ18O measurements on the planktic foraminifers Globigerinoides ruber and Globorotalia crassaformis and determine abundances of the subpolar foraminifer Neogloboquadrina atlantica. We find that the first significant glacial incursions of Subarctic Front surface waters above Site U1313 did not occur until ~2.6 Ma. At no time during our study interval was (sub)surface reorganization in the midlatitude North Atlantic analogous to the LGM. Our findings suggest that LGM‐like processes sensu stricto cannot be invoked to explain interglacial‐glacial cycle amplification during iNHG. They also imply that increased glacial productivity at Site U1313 during iNHG was not only driven by southward deflections of the Subarctic Front. We suggest that nutrient injection from cold‐core eddies and enhanced glacial dust delivery may have played additional roles in increasing export productivity in the midlatitude North Atlantic from 2.7 Ma.
Targeting of the respiratory chain by toxicants: beyond the toxicities to mitochondrial morphology
Authors: Zhou P. K. , Huang R. X. 
Published: September 2018

Abstract
The mitochondrion is an important subcellular target of environmental toxicants. With environmental stress, a series of toxic effects on mitochondria are induced, which originate from the dynamic changes of mitochondrial fusion and fission, structure/membrane damage, and respiratory chain dysfunction. The toxic effects of various toxicants on mitochondrial morphology and intact membranes, and their determination of cell fate, have already been broadly studied and reported on. However, their effects on the integrity and function of the mitochondrial respiratory chain (RC) remain incompletely understood. Recently, Fan et al. and Yu et al. approached this topic by closely examining the mitochondrial toxicities, including the effect on the respiratory chain, induced by organic arsenical chemical 2-methoxy-4-(((4-(oxoarsanyl)phenyl)imino)methyl)phenol and thiourea gold(i) complexes (AuTuCl). Obviously, toxicant-induced dysfunction of the respiratory chain can hinder ATP production, and may elevate ROS generation. The increased ROS can further damage mtDNA, and consequently leads to inactivation of some RC protein-encoding mtDNA, generating a vicious circle of amplifying mitochondrial damage. We hope that these studies focused on RC structure and activity will broaden our view of mitochondrial toxicology and draw forth more profound mechanistic studies on the respiratory chain toxicity of environmental toxicants and their application in risk assessment.
Modifying Food Textures: Practices and Beliefs of Staff Involved in Nutrition Care
Authors: Garcia Jane Mertz , Chambers Edgar , Russell Emily Groves , Katt Abilene 
Published: September 2018

Purpose
Modifying food texture is an important part of dysphagia management, yet less is known about the day-to-day practices that might impact the nutritional well-being of patients. This study surveyed staff involved in the service delivery of texture-modified foods with the objectives to gain information about roles and responsibilities, instruction and knowledge about modifying foods, and beliefs about the use of texture-modified foods in nutrition care.

Method
We created a 21-item survey about texture-modified foods. Recruitment efforts focused on both professional and frontline staff involved in service delivery. Practice groups and organizations provided the means of recruiting professionals from different disciplines. Because frontline staff (e.g., certified nursing assistants, cooks) do not have similar membership groups, we recruited them through direct contacts with health care agencies.

Results
A total of 175 individuals completed the survey. Respondents included 107 professionals (primarily certified dietary managers, registered dietitians, speech-language pathologists) and 68 frontline staff (mostly certified nursing assistants/home health aides). Although the frontline and professional staff showed generally similar patterns of opinions and beliefs about modified food textures, differences emerged in reported experiences, roles, and responsibilities in service delivery.

Conclusions
Survey respondents conveyed generally positive attitudes and opinions about the use of texture-modified foods, and respondents perceived them to be easy to execute and beneficial to the nutritional well-being of patients. Survey findings clearly highlight the contributions of frontline staff in the service delivery of modified food textures. Consideration must be given to continued reliance on informal, limited instruction about texture-modified foods and possible implications for safe nutrition care. Both professional and frontline staff convey a willingness to customize or alter food textures and the belief that patients should be able to choose the level of texture modification that they want to eat.
Effectiveness of a Preexternship Hospital Orientation Program for Graduate Students in Speech-Language Pathology
Authors: Warner Heather , Karlberg Amy , Purdy Mary 
Published: September 2018

Purpose
A preexternship hospital orientation program was developed in response to clinical externship supervisors providing feedback that students were not well prepared when entering the medical setting for the 1st time. This program aimed to introduce students to different medical settings where they could observe patients with a range of communication and swallowing disorders and their interactions with a speech-language pathologist.

Method
Students shadowed speech-language pathologists for a half-day at 4 different medical locations throughout the program. Forty-two students filled out pre- and postorientation surveys detailing their experiences and learning outcomes.

Results
An analysis of pre–post surveys indicates that students perceived a gain in working knowledge of several key areas, including assessment protocols, job demands, documentation, and interprofessional collaboration. Students also reported that the experience allowed them to make an informed choice regarding the type of externship or job they wished to pursue in the future.

Conclusion
Students reported favorable outcomes as a result of this observational experience. Clinical exposure programs should be considered as a modality for learning for speech-language pathology students.
IVH-Prävention bei ELBW-Frühgeborenen in zwei Perinatalzentren
Authors: Cipowicz Clara , Schmid Manuel , Hummler Helmut , Thome Ulrich 
Published: September 2018

Zusammenfassung
Hintergrund Im Rahmen eines Projekts zur konsequenten Vermeidung zahlreicher bekannter Risikoindikatoren sank die Inzidenz von intraventrikulären Hämorrhagien (IVH) am Ulmer Perinatalzentrum. Ein Vergleich mit dem Leipziger Zentrum sollte Hinweise liefern, an welchen Stellen es an beiden Zentren noch Verbesserungsmöglichkeiten gibt.
Methoden Eine retrospektive Datenerhebung wurde für 189 Leipziger und 89 Ulmer Frühgeborene mit einem Geburtsgewicht von unter 1000 g durchgeführt. Für diese Daten wurde ein Vergleich zwischen den beiden Zentren durchgeführt.
Ergebnisse Eine IVH aller Schweregrade wurde in Leipzig (56/197, 28,4%) häufiger (p=0,01) als in Ulm (13/89, 14,6%) gefunden. Der Unterschied betraf nur die leichten IVH Grade 1–2; die Inzidenz der schweren IVH (Grad 3–4) unterschied sich nicht zwischen den beiden Zentren (p=0,59, Leipzig 12/197, 6,1%; Ulm 4/89, 4,5%). Weiterhin zeigte sich bei einzelnen IVH-Risikoindikatoren eine unterschiedliche Verteilung zwischen den beiden Zentren. So trat eine postnatale Hypokapnie in Leipzig (42/197, 21,3%) häufiger auf (p<0,01) als in Ulm (3/86, 3,5%). Auch eine postnatale Hypothermie ereignete sich häufiger (p<0,01) in Leipzig (53/197, 26,9%) als in Ulm (10/89, 11,2%). In Ulm wurde hingegen eine rasche postnatale Surfactantapplikation seltener (p<0,01) durchgeführt (32/60, 53,3%) als in Leipzig (136/158, 86,1%) und Bikarbonat wurde in Ulm häufiger gegeben (48/89, 46,1% gegenüber 183/197, 7,1%, p<0,01).
Schlussfolgerung Potenziell vermeidbare Risikofaktoren traten in beiden Zentren in unterschiedlicher Häufigkeit auf. Diese Ergebnisse ermöglichen es beiden Zentren, die jeweils mit erhöhte Häufigkeit aufgetretenen Risikofaktoren gezielt zu vermeiden und so die IVH-Rate weiter abzusenken.
Glans Ischemia after Circumcision in a 16-Year-Old Boy: Full Recovery after Angiography with Local Spasmolysis, Systemic Vasodilatation, and Anticoagulation
Authors: Gnatzy Richard , Fuchs Jochen , Siekmeyer Manuela , Beeskow Anne , Gosemann Jan-Hendrik , Lacher Martin 
Published: September 2018

AbstractCircumcision is one of the most frequent procedures performed by pediatric surgeons. A dorsal penile nerve block (DPNB) is commonly used for perioperative analgesia. We report the case of a 16-year-old boy with ischemia of the glans who presented on the first postoperative day after circumcision under DPNB (0.25% bupivacaine) at an outside hospital. The patient underwent immediate angiography under sedation. An intra-arterial spasmolysis was performed with alprostadil and nitroglycerine and a sufficient perfusion of the glans penis was confirmed. Subsequently, systemic sildenafil, arginine, and heparin were given. Following this 3-day medical treatment, ischemia resolved completely. Our case emphasizes the role of invasive angiography in the diagnostic workup and the therapeutic possibilities of local spasmolysis, systemic vasodilatation, and anticoagulation.
Pulmonary Metastasectomy of Sarcoma: Is the Ratio of Surgical Margin to Nodule Size a Prognostic Factor?
Authors: Özdil Ali , Tekneci Ahmet Kayahan , Dökümcü Zafer , Divarcı Emre , Keçeci Burçin , Sezak Murat , Çakan Alpaslan , Çağırıcı Ufuk 
Published: September 2018

Background Main prognostic factors of improved survival after pulmonary metastasectomy (PM) for osteogenic and soft tissue sarcomas are suggested as histological type, number and size of pulmonary nodules, and disease-free interval (DFI).
Methods Sixty-nine patients who underwent PM between January 1999 and December 2017 were evaluated retrospectively. Relations between parameters and prognostic risk factors for overall survival (OS) and disease-free survival (DFS) were evaluated.
Results Osteosarcoma was the most common histologic type (36.2%) and 21 of 25 cases were seen under the age 20 years (p < 0.001). Comparison of patient groups including osteosarcoma and nonosteosarcoma patients showed significant difference according to age (p < 0.001), nodule size (p = 0.033), ratio of surgical margin to nodule size (p = 0.007), and DFI (p = 0.039). Univariate analysis showed that the number of nodules (p = 0.008), ratio of surgical margin to nodule size (p = 0.001), and localization of nodule (p = 0.039) were significant factors associated with DFS. Also, nodule size (p = 0.042), number of nodules (p = 0.003), ratio of surgical margin to nodule size (p < 0.001), and laterality (p = 0.027) were significant prognostic factors associated with OS. Cut-off values of ratio of surgical margin to nodule size for DFS and OS were calculated as 0.94. Logistic regression analysis determined the ratio of surgical margin to nodule size as the common significant risk factor for DFS and OS.
Conclusions Our study showed that the ratio of surgical margin to nodule size ≥ 1 should be taken as a common risk factor for DFS and OS. Therefore, resection of nodules with the possible widest surgical margin is an important point of PM.
Genetics And Periodontium: A Review
Authors: Singh Baljeet , Garg Avnika , Nayyar Nandini , Sharma Alka 
Published: September 2018

AbstractPeriodontal disease may be regarded as a range of different diseases for which certain individuals are at relatively high risk. Epidemiological and molecular studies of the oral microbial flora suggest, that although microbial factors are required for periodontal disease, they alone do not predict the presence or severity of periodontitis. So in high-risk patient groups, host factors appear to play an important role in susceptibility to periodontitis. In recent years elements of host susceptibility, such as immune response and systemic disease state, and other non-microbial environmental factors, such as smoking, have been shown to be important contributors to the disease expression. Thus, periodontitis represents a lifelong account of interactions between our genome, our behavior, and our environment.
Polymerase Chain Reaction: A Powerful Diagnostic and Research Tool
Authors: Jain Kanu , Mehendiratta Monica , Jindal Deepti , Bansal Mohit 
Published: September 2018

AbstractTo fully understand cellular processes, scientists often examine events at the level of nucleic acids and protein molecules. These studies are complicated by the fact that cells have miniscule amounts of molecules of interest which are too small to be seen. So we require molecular tools to visualize these molecules. Polymerase chain reaction is one such technique widely used in molecular biology and produce quantities that are sufficient to study and visualize. With the advancement in this technique, it has revolutionized the field of research and diagnosis. In this article, we present a review on the principle, basic technique, applications, limitations and recent advances of Polymerase Chain Reaction.
A Study to Evaluate Life Span of Crowns & Fixed Partial Dentures and Various Reasons of their Failures
Authors: Singh Gursharan , Madan Nishtha , Kumar Mandeep , Walia Cherry , Singh Opinder 
Published: September 2018

AbstractMost patients are concerned about the anticipated length of service and reasons of replacement of fixed dental prostheses (FPDs). This study tried to find out relationship among various factors causing failures in fixed dental prostheses. Patients treated with fixed dental prostheses were examined clinically and radiographically. A group of 106 patients were evaluated for unsatisfactory restorations. These groups of patients produced records of initial treatment to ascertain the length of service of restoration. The mean survival period of fixed dental prostheses was 7.5 years. This investigation helped find causes for failures and survival period of various FPDs. Among the reasons of failures, caries was the most frequently observed (24.2%), followed by defective margin (18.2%), unsatisfactory esthetics (15.2%), retention problem (11.7%), periodontal disease (8.8%), fractured tooth (10.6%), periapical lesion (5.8%), porcelain fracture (4.2%) and others (1.3%). Causes of failures were also grouped into two groups (Mechanical & Oral diseases) for comparison. The Mechanical group showed higher failure percentage (59.9%) as compared to Oral diseases group (38.8%).
A New Geometric Intersection Point (Ms) to Determine the Spatial Position of Maxillary Sinus
Authors: Singh Sarabjeet , Gautam Mukti , Kashyap Rita , Sandhu Gurinderpal , Singla Divya 
Published: September 2018

Abstract
Introduction: Cephalometeric landmark detection, is a knowledge intensive activity to identify on standardized lateral x-rays of the skull, to perform measurements needed for medical diagnosis, treatment planning and evaluation. For computation of analysis of steps and for determination of underlying structures, provided landmarks should be correctly localized. Due to the complexity of human anatomy sensed in a cephalometric x-ray, the landmarks are localized and constructed. Maxillary sinus has an important role to play in the formation of facial contours. Objective: Our aim is to check the validity of new geometric intersection point Ms, evaluating cephalometerically the spatial position of maxillary sinus and to find any correlation between the spatial position of maxillary sinus and sagittal dysplasias. Study design: A single-institution prospective analysis. Subjects and methods: A total of 20 lateral cephalograms were used, of both sexes, ranging in age from 18-25 years. These radiographs were from subjects, classified into class I and class II on the bases of ANB and Ao-Bo. Maxillary sinus was carefully analyzed and measured in linear dimensions of length and width and its spatial position was calculated by using a new geometric intersection point Ms, created by the intersection of the linear measurements, in relation to the anterior cranial base. The spatial position of maxillary sinus was calculated from the position of the intersection point Ms. The length and height of maxillary sinus was measured and compared in both the groups. Results: The mean of maxillary sinus length (MSL) and height (MSH) was 43.2 ± SD 3.2mm and 41.2 ± SD 3.8mm, respectively for classI (p value=0.595) and 44.2 ± SD 4.9mm and 43.0 ± SD 3.4mm, respectively for class II (p value=0.283). The intersection point Ms depicting centre of maxillary sinus from x-axis (Ms-Msx) was same for both the groups. Mean for Ms-Msy, was 37.3 ± SD 5.7 for class I and 37.8 ± SD 1.9 for class II (p value=0.796). No statistical significance was found among the results in both the groups. Conclusion: The length and height of maxillary sinus was calculated and the centre of maxillary sinus was calculated by the intersection of the two. This new point can contribute in calculating the spatial position of sinus and be an effective measure to study the convexity and concavity of the midface. In the present study, the length and height of the sinus did not alter with the increased or decreased ANB and Ao-Bo. There was no significant spatial position change of maxillary sinus with variation in ANB and Ao-Bo (sagittal). Regarding vertical parameters, Ms may have significant correlation with the various malocclusions.
Microleakage Evaluation of Nano Ceramics and Nano Composite Resins Using Self Etch Adhesive in Class V Cavities Using Single Increment Technique
Authors: Singh S. Vijay , Gupta Saurabh , Jain Pragya , Munjal Vaibhav 
Published: September 2018

AbstractMicro leakage plays an important role in the success of composite restoration, this have led to researcher to find newer composite restorative material with present study it was observed that Self-etch adhesive systems and single increment technique are advantageous in that it reduces the application time and technique related sensitivity.