bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of corporate governance on earnings quality: evidence from Peru
Authors: Melgarejo Mauricio 
Published: October 2019

PurposeThe purpose of this paper is to explore whether firms with good corporate governance practices in countries with high levels of political and economic uncertainty, such as Peru, present a higher quality of accounting information.Design/methodology/approachThis study uses a multivariate regression analysis to investigate the impact of good corporate governance practices on the quality of accounting information for the firms listed in the Lima Stock Exchange (LSE).FindingsFirms included in the Good Corporate Governance Index, in the LSE, present more value relevant, more persistent and more conservative accounting reports. These results hold after controlling for a self-selection bias.Originality/valueIt is the first paper to explore the impact of good corporate practices on earnings quality in Peru. Also, this study uses a two-state regression methodology to control for the self-selection bias in the sample.
Social networking sites and customers’ attitude towards advertisements
Authors: Mukherjee Kaustav , Banerjee Neelotpaul 
Published: October 2019

Purpose
The study aims to demonstrate the impact of social media users’ positive attitude towards the social networking sites (SNS) on the generation of a positive attitude towards social networking advertisements (SNA). A favourable attitude towards the SNA thus generated can positively influence brand attitude and purchase intention.

Design/methodology/approach
An online survey was conducted to collect relevant data using a structured questionnaire. Structural equation modelling was conducted using the statistical software AMOS 18.

Findings
Empirical analysis revealed the importance of brand advertisements on the social networks in inciting a positive attitude as well as a purchase intention for the brand in the SNS users’ minds.

Research limitations/implications
The study has been conducted in the Indian context using Facebook as a model social networking site.

Practical implications
Social media being one of the most popular and user-friendly platforms for regular communications, marketers are suggested to allocate a sizeable share of the advertising budget for social media advertisements and customer engagement so as to help build a positive attitude towards the advertised brand in the SNS users’ minds.

Originality/value
To the best of the authors’ knowledge, the impact of users’ positive evaluation of SNS as an effective communication medium, on the generation of a positive attitude towards the SNA, has been dealt for the first time here.
Factors for improving performance in ISO 9001 certified small- and medium-sized service enterprises
Authors: Chiarini Andrea , Castellani Paola , Rossato Chiara 
Published: October 2019

Purpose
The purpose of this paper is to investigate the factors that are important for improving the performance of ISO 9001 certified small- and medium-sized service enterprises (SMSEs).

Design/methodology/approach
Preliminary research questions were set on the basis of a literature review and then submitted to a Delphi panel of experts. The results from the Delphi panel were transformed into hypotheses in the form of a survey. A sample comprising 115 Italian SMSEs answered the survey, which also included specific fields for qualitative notes. The hypothesis tests used 95% confidence intervals, and notes and suggestions from the respondents were also collected.

Findings
The findings relate to the role and responsibilities of the quality manager, as well the entrepreneur and partners, the quality of the enterprise culture, training, awareness concerning process key performance indicators, visual management and modern digitised documentation and communication. Furthermore, criticisms emerged regarding the ISO 9001 standard in terms of cost of quality measurement, day-to-day improvement and problem-solving.

Research limitations/implications
This research is limited to SMSEs. The limitations of this research open avenues for further research. In particular, many suggestions from the respondents seem generalisable to other industries and also to large manufacturing firms.

Practical implications
The findings of this research could be used as a guideline for implementing ISO 9001 in the SMSE sector. Moreover, some of the criticisms could be taken into account for the next revision of the ISO 9001 standard.

Originality/value
This is one of the first papers to discuss important factors for improving the performance of ISO 9001 in the SMSE sector.
The UNTOLD story
Authors: Moisescu Ovidiu Ioan , Gică Oana Adriana , Coroș Monica Maria , Yallop Anca C. 
Published: October 2019

Purpose
This paper aims to examine the negative effects of events on residents’ quality of life. Particularly, the paper analyses the specific negative effects generated via “overtourism” for the duration of large-scale music festivals.

Design/methodology/approach
The paper uses a case study method approach to examine the negative effects that UNTOLD, the largest music festival in Romania, has on residents’ quality of life. The case is analysed via a comprehensive desk research of secondary data from industry and academic sources.

Findings
Despite its success and the positive economic impact UNTOLD festival had on the host city, several issues have a negative impact on residents’ quality of life and well-being. The negative impacts are noise pollution, vandalism and crime, traffic and parking issues, waste and damages to the natural environment, pressure on and over usage of local services and infrastructure and the increased cost of living.

Social implications
Whilst organisers, local businesses and local authorities are the main parties benefiting from events, residents mainly feel the negative impact. Organisers, local authorities and businesses need to minimise the negative effects residents’ experience during the event by building sustainable partnerships and taking a more hands-on approach to sustainable and socially responsible practices. Current and potential initiatives are discussed in the paper.

Originality/value
This paper examines the negative impacts events may have on residents’ quality of life and discusses the case of a large-scale music festival, an under-researched context. The analysis and discussion may assist scholars and industry experts alike in generating new debates in sustainable event management practices, as well as festival organisers and public authorities in developing strategies for avoiding, containing or minimising the negative effects of events.
Perceptions of tourism-related non-governmental organization (NGO) managers in Antalya
Authors: Akbulut Onur , Ekin Yakin 
Published: October 2019

Purpose
The purpose of this paper is to investigate the perceptions of tourism-related non-governmental organization (NGO) managers on overtourism trends in Antalya, Turkey.

Design/methodology/approach
Focus group study was implemented and three focus group interviews were undertaken with 34 NGO managers in total as a sample. The population of the research consisted of 65 tourism-related NGO managers in Antalya.

Findings
The results of the research reveal that Antalya was perceived as neither in a tourism development stage nor afflicted by overtourism by NGO managers. NGOs are one of the major stakeholders in the tourism industry, and hence their perceptions of overtourism would probably be the stimulating force for further sustainable development in the destination.

Research limitations/implications
The limitation is that the research was realized voluntarily by 34 NGOs in Antalya. It would have been better to have more volunteer respondents.

Practical implications
The viewpoints of stakeholders about their perceptions of tourism development in Antalya would be a helpful next step to refer back to practitioners so as to develop further strategic plans from their perspectives.

Social implications
As social exchange theory states, communities benefiting from tourism development will support further improvement in tourism. Hence, in their role as spokespersons for the community, the perceptions of NGOs will influence decision-makers to draw implications from the study for wider consideration.

Originality/value
As a consequence, a model was proposed according to the results of the research. The findings of the research paper highlight the evolution of high-flow tourism in the destination.
Overtourism: a result of the Janus-faced character of the tourism industry
Authors: Avond Guillaume , Bacari Chaarani , Limea Isabelle , Seraphin Hugues , Gowreesunkar Vanessa , Mhanna Rami 
Published: October 2019

Purpose
This paper aims to evaluate the “Janus-faced” character and causes of overtourism to propose recommendations to tackle such a phenomenon.

Design/methodology/approach
A case study analysis approach is adopted for this study. Studies of practitioners are presented and reflected upon with reference to academic literature on overtourism.

Findings
The study presents practical examples from Haiti, Nicaragua and Zanzibar. Tourism practitioners’ studies on overtourism are presented and general recommendations on tackling overtourism are proposed.

Research limitations/implications
This study will be of interest to tourism practitioners and Destination Marketing Organisations (DMOs) worldwide who seek understanding of the overtourism phenomenon and the associated negative impacts. The study provides useful recommendations that can be used in similar situations of overtourism.

Originality/value
The paper extends understanding of overtourism causes and consequences. While overtourism is generally looked at from impact studies, this paper argues the urgent need for solutions to tackle the phenomenon.
Spreading tourists around host countries of mega sport events
Authors: Mhanna Rami , Blake Adam , Jones Ian 
Published: October 2019

PurposeThis study aims to recommend initiatives that can be adopted to overcome overtourism in host destinations of mega sport events.Design/methodology/approachThis study adopts a qualitative research design that involves 20 semi-structured interviews with key informant stakeholders of the London 2012 Olympic Games. An exploratory case study approach was used to investigate strategies used to leverage tourism benefits in host destinations, and the authors used thematic analysis to present strategies to overcome overtourism in host cities.FindingsThis study emphasises the need for spreading tourists beyond the host city as a main strategy. To do so, three initiatives are recommended: spreading domestic tourism outside the host city, showcasing destination beyond the host city and promoting regional collaboration.Practical implicationsThis research provides tourism practitioners and destination management organisations in host destinations of mega sport events with an advanced strategic insights to capitalise on mega sport events. The authors suggest considering the events as athemethrough an event planning process to overcome potential overtourism in unique host cities.Originality/valueAs overtourism has an impact on visited destinations, this study argues that overtourism can be generated by mega sport events. This paper offers an extended insight into overcoming overtourism by implementing strategic event tourism, leveraging initiatives that can be extended in use to reach geographic areas beyond host cities of mega sport events.
Introduction
Authors: Gowreesunkar Vanessa , Seraphin Hugues 
Published: October 2019

Purpose
This paper aims to provide an overview of the significance of this theme issue. To develop a better understanding of the context, the phenomenon of overtourism is introduced. The paper also sheds light on perverse impacts of overtourism on key stakeholders and seeks to provide justification for the need for smart and sustainable strategies.

Design/methodology/approach
The research design follows a mixed approach and draws from a combination of case studies, online sources, literature reviews and an industry paper. This combination of primary, secondary and tertiary data enables more meaningful analysis of overtourism from destinations with different specificities and characteristics.

Findings
The paper provides valuable insight on the causes and consequences of overtourism on the destination and its people, which arguably include both tourists, residents and other stakeholders. Based on empirical evidence, the paper presents common strategies that are used to tackle overtourism and seeks to draw insights from those case studies to propose smarter and more sustainable strategies.

Originality/value
The value of this theme issue is that it presents a variety of case studies that might be used as examples to mitigate the consequences of overtourism. Destinations showing similar symptoms may draw from the paper to manage the strain of overtourism. As one size does not fit all, the variety of strategies proposed within those papers might help practitioners and destination managers to select and adapt them to their respective contexts. Further, the research findings may be applicable to other geographic regions with similar contexts.
Reflections on the theme issue outcomes
Authors: Gowreesunkar Vanessa , Seraphin Hugues , Teare Richard 
Published: October 2019

Purpose
The purpose of this paper is to summarise the main outcomes of the collection of studies in this theme issue and to offer some key reflections based on the experiences of the theme editors and contributors.

Design/methodology/approach
This study uses structured questions to enable the theme editors to reflect on the rationale for the theme issue question, the starting point, the selection of the contributors and material and the editorial process.

Findings
This paper provides insights and practical suggestions in response to the theme issue question from different academic and professional backgrounds, namely, the hotel industry, the events industry, the technology sector, non-governmental organisations, government sectors, and the local community.

Practical implications
The theme issue outcomes provide lines of enquiry for others to explore and reinforce the value of worldwide hospitality and tourism theme’s approach to collaborative working and writing.

Originality/value
The collaborative study reported in this theme issue offers a unified but contrarian response to the theme’s strategic question. Taken together, the papers provide a range of options for destination marketing organisations in response to the issues highlighted.
Morphine stimulates angiogenesis through Akt/mTOR/eIF4E activation under serum deprivation or H2O2‐induced oxidative stress condition
Authors: Zhang Kun , Huang Wei , Chen Wei , Zhou Qian , Zhang Qiongxia , Wu Xiaoqin , Xu Yong , Li Dezhan , Xie Tao , Liu Jie 
Published: October 2019

AbstractMorphine is an opioid analgesic drug routinely used to treat pain in several medical conditions including cancer. Increasing evidence has shown that morphine can directly modulate cancer growth via regulating angiogenesis. In this work, we investigated the effect of morphine on angiogenesis under pathological conditions. We showed that morphine, in a concentration typical of that observed in patient's blood, stimulates tumour angiogenesis under serum deprivation and H2O2‐induced oxidative stress conditions. We found that morphine protected human lung tumour associated‐endothelial cell (HLT‐EC) against serum deprivation or H2O2‐induced inhibition of capillary network formation. Furthermore, morphine stimulated other biological functions of HLT‐EC under serum deprivation and H2O2‐induced pathological conditions, such as growth, migration and survival, without affecting HLT‐EC adhesion. Interestingly, morphine at the same concentration did not affect lung tumour cell growth and survival, suggesting the specific protective role of morphine at low micromolar concentrations on tumour angiogenesis. Using in vivo Matrigel angiogenesis assay, it was found that morphine stimulated in vivo angiogenesis under H2O2‐induced pathological condition. The opioid receptor antagonist, naloxone, did not inhibit the protective activity of morphine in in vivo angiogenesis, indicating that the effect was less likely to be mediated by the typical opioid receptors. Mechanism analysis indicated that morphine alleviated serum deprivation and H2O2‐induced angiogenesis inhibition via reducing oxidative stress and damage, and activating Akt/mTOR/eIF4E signalling. We demonstrate the protective role of morphine on tumour angiogenesis under pathological conditions. Our work suggests that clinical use of morphine may be harmful in patients with angiogenesis‐dependent cancers.
A New Chapter in the Normalisation of Closed Material Procedures
Authors: Lock Daniella 
Published: October 2019

AbstractThis note provides an analysis of the Supreme Court decision in Haralambous, which authorised the use of closed material procedures (CMPs) in proceedings surrounding search and seizure warrants issued under the Police and Criminal Evidence Act 1984 (PACE). After presenting the facts of the case and the reasoning of the Court, the note examines the decision as an instance of CMP normalisation consistent with the model of normalisation argued for by Eva Nanopoulos in a previous MLR article. The notes goes on to make the case that Haralambous may be distinguished from previous instances of CMP normalisation on account of the Supreme Court's more open acceptance of CMPs in the decision, which signals a new chapter in CMP normalisation in the UK.
Enzymatic Production, Bioactivity, and Bitterness of Chickpea (Cicer arietinum) Peptides
Authors: Real Hernandez Luis M. , Gonzalez de Mejia Elvira 
Published: October 2019

AbstractChickpeas are inexpensive, protein rich (approximately 20% dry mass) pulses available worldwide whose consumption has been correlated with positive health outcomes. Dietary peptides are important molecules derived from dietary proteins, but a comprehensive analysis of the peptides that can be produced from chickpea proteins is missing in the literature. This review provides information from the past 20 years on the enzymatic production of peptides from chickpea proteins, the reported bioactivities of chickpea protein hydrolysates and peptides, and the potential bitterness of chickpea peptides in food products. Chickpea peptides have been enzymatically produced with pepsin, trypsin, chymotrypsin, alcalase, flavorzyme, and papain either alone or in combination, but the sequences of many of the peptides in chickpea protein hydrolysates remain unknown. In addition, a theoretical hydrolysis of chickpea legumin by stem bromelain and ficin was performed by the authors to highlight the potential use of these enzymes to produce bioactive chickpea peptides. Antioxidant activity, hypocholesterolemic, and angiotensin 1‐converting enzyme inhibition are the most studied bioactivities of chickpea protein hydrolysates and peptides, but anticarcinogenic, antimicrobial, and anti‐inflammatory effects have also been reported for chickpea protein hydrolysates and peptides. Chickpea bioactive peptides are not currently commercialized, but their bitterness could be a major impediment to their incorporation in food products. Use of flavorzyme in the production of chickpea protein hydrolysates has been proposed to decrease their bitterness. Future research should focus on the optimization of chickpea bioactive peptide enzymatic production, studying the bioactivity of chickpea peptides in humans, and systematically analyzing chickpea peptide bitterness.
Diversity and dynamics of microbial communities in brown planthopper at different developmental stages revealed by high‐throughput amplicon sequencing
Authors: Wang Zheng‐Liang , Wang Tian‐Zhao , Zhu Hang‐Feng , Pan Hai‐Bo , Yu Xiao‐Ping 
Published: October 2019

AbstractThe microbiome associated with brown planthopper (BPH) plays an important role in mediating host health and fitness. Characterization of the microbial community and its structure is prerequisite for understanding the intricate symbiotic relationships between microbes and host insect. Here, we investigated the bacterial and fungal communities of BPH at different developmental stages using high‐throughput amplicon sequencing. Our results revealed that both the bacterial and fungal communities were diverse and dynamic during BPH development. The bacterial communities were generally richer than fungi in each developmental stage. At 97% similarly, 19 phyla and 278 genera of bacteria were annotated, while five fungal phyla comprising 80 genera were assigned. The highest species richness for the bacterial communities was detected in the nymphal stage. The taxonomic diversity of the fungal communities in female adults was generally at a relatively higher level when compared to other developmental stages. The most dominant phylum of bacteria and fungi at each developmental stage all belonged to Proteobacteria and Ascomycota, respectively. A significantly lower abundance of bacterial genus Acinetobacter was recorded in the egg stage when compared to other developmental stages, while the dominant fungal genus Wallemia was more abundant in the nymph and adult stages than in the egg stage. Additionally, the microbial composition differed between male and female adults, suggesting that the microbial communities in BPH were gender‐dependent. Overall, our study enriches our knowledge on the microbial communities associated with BPH and will provide clues to develop potential biocontrol techniques against this rice pest.
5α‐Reductase type 2 deficiency in families from an isolated Andean population in Venezuela
Authors: Avendaño Andrea , González‐Coira Mercedes , Paradisi Irene , Rojas Ascanio , Da Silva Gloria , Gómez‐Pérez Roald , Ceballos Jesús Osuna 
Published: October 2019

Abstract5α‐Reductase type 2 deficiency causes a 46,XY disorder of sex development (DSD) characterized by ambiguous external genitalia, rudimentary prostate, and normal internal genitalia. The disease prevalence worldwide is low, but in a small and isolated village of the Venezuelan Andes, a higher incidence has been found. DNA analysis of the SRD5A2 gene was performed in three inbred affected individuals clinically diagnosed with DSD. The entire coding regions, the p.L89V polymorphism (rs523349) and five intragenic SNPs (rs2300702, rs2268797, rs2268796, rs4952220, rs12470196) used to construct haplotypes were analyzed by Sanger sequencing. To assess the probable ethnic origin of the mutation in this geographic isolate, a population structure analysis was performed. Homozygosis for the p.N193S mutation was found in all patients, with a mutation carrier frequency of 1:80 chromosomes (0.0125) in the geographic focus, suggesting a founder phenomenon. The results of the population structure analysis suggested a mutation origin closer to the Spanish populations, according to the clusters grouping. The genotype–phenotype correlation in the patients was not absolute, being hypospadias and cryptorchidism the main traits that differentiate affected individuals.