bluuebunny/crossref_metadata_2025_split huggingface dataset:
ABSORÇÃO E TRANSLOCAÇÃO DE SILÍCIO EM MUDAS DE <i>Eucalyptus camaldulensis</i>
Authors: Queiroz Dalva Luiz de , Camargo Joelma Melissa Malherbe , Dedecek Renato Antonio , Oliveira Edilson Batista de , Zanol Keti Maria Rocha , Melido Raul Cesar Nogueira 
Published: June 2018

A busca pela alta produtividade e qualidade das plantas de eucalipto que sejam mais resistentes ao ataque de insetos-praga vem sendo cada vez mais estudada. Dentro deste contexto, realizou-se o estudo da absorção e a translocação de silício em plantas de Eucalyptus camaldulensis. O experimento foi realizado com o clone 58, em viveiro comercial da empresa Votorantim Siderurgia /João Pinheiro-MG, onde foi avaliada a aplicação de silício via solo (silicato de cálcio) e via foliar (silicato de potássio), com três doses diferentes. O delineamento experimental foi inteiramente casualizado, com oito tratamentos, 20 repetições, totalizando 160 plantas. A avaliação do experimento foi realizada com base na análise do teor de silício presente no substrato (%) e na matéria seca das raízes e parte aérea das plantas (mg planta-1). Foram realizadas três avaliações aos 30, 60 e 90 dias após aplicação das doses de silício em folhas e raízes. Para o substrato foram realizadas quatro avaliações, sendo a primeira no dia da instalação do experimento (antes da aplicação de Si) e as demais aos 30, 60 e 90 dias após semeadura do eucalipto. Nas análises foliares realizadas, os maiores valores em relação ao teor de silício foram observados para o tratamento com aplicação de silicato de potássio (10mL/planta), T8, que foi em média 3 vezes maior, quando comparado aos tratamentos sem aplicação de silício (adubação padrão+110 gramas de CaO) - T1 e sem aplicação de silício (adubação padrão+1,71gramas de KCl) – T2. Os tratamentos não diferiram estatisticamente entre si nas avaliações realizadas, em relação à percentagem de silício presente nas raízes de E. camaldulensis. No substrato verificou-se um aumento significativo no teor do mineral aos 30, 60 e 90 dias, em função das doses crescentes de silicato, nas duas formas de aplicação, destacando o T8. Assim, foi possível concluir que E. camaldulensis é capaz de absorver e translocar o mineral.
RESISTÊNCIA À GEADA E CRESCIMENTO INICIAL DE <i>Toona ciliata</i> EM CULTIVOS CONSORCIADOS COM <i>Eucalyptus grandis</i> EM DIFERENTES ADUBAÇÕES
Authors: Da Ros Clovis Orlando , Perrando Edison Rogerio , Paula Gizelli Moiano de , Somavilla Lucindo , Predige Daylien Mayane Sossmeier Albring , Engel Kauana , Silva Rodrigo Ferreira da 
Published: June 2018

A restrição nutricional e a ocorrência de geadas no sul do Brasil frequentemente afetam o crescimento de cultivos florestais. Com o objetivo de quantificar o crescimento inicial e a resistência à geada das plantas de Toona ciliata em cultivos consorciados com Eucalyptus grandis, com diferentes adubações, foi conduzido um experimento na UFSM, campus de Frederico Westphalen. O delineamento experimental foi de blocos ao acaso com três repetições, no arranjo fatorial 2 x 2 x 3: duas espécies florestais (Eucalyptus grandis Hill ex Maiden e Toona ciliata M. Roem var. australis), dois tipos de cultivos (solteiro e consorciado) e três tipos de adubação (NPK, NPK + Si e NP de liberação lenta + K + bioestimulante). O crescimento em altura das plantas foi mensurado em datas diferenciadas até 346 dias após o plantio. No final deste período foi quantificado o diâmetro a altura do peito e a massa seca da parte aérea. A avaliação do nível de danos às plantas e o grau de resistência à geada foi feito com atribuição de notas com base nas plantas inteiras e nas copas das plantas. Os dados foram submetidos à análise de variância e, quando significativa (p ≤ 0,05), procedeu-se a comparação das médias dos tratamentos pelo teste de Tukey (p ≤ 0,05). As duas espécies florestais foram tolerantes à geada, mas com maior dano na área foliar nas plantas de Toona ciliata em relação a Eucalyptus grandis. O cultivo de Toona ciliata sob proteção de Eucalyptus grandis não diminuiu os danos da geada no primeiro ano de implantação no campo. O uso de fertilizante de liberação lenta, de Si e de bioestimulante não contribuíram para aumentar o crescimento e a resistência à geada das plantas das duas espécies florestais.
Producción científica española en turismo: Un análisis de autoría basado en revistas internacionales con alto impacto y visibilidad
Authors: López-Bonilla José Manuel , Granados-Perea Concepción , López-Bonilla Luis Miguel 
Published: June 2018

<p>El presente estudio se ha centrado en el análisis de la producción científica con difusión internacional de los autores afiliados a instituciones españolas. La búsqueda se ha realizado a través de la base de datos de Scopus durante el período 2002-2013. Especialmente, se han analizado los trabajos publicados en revistas científicas que están incluidas en el Journal Citation Reports (JCR). Entre otros hallazgos, hay una gran concentración de autores que pertenecen a los ámbitos de la economía y la empresa. Las revistas científicas más utilizadas han sido Tourism Management y Tourism Economics. </p>
Recombinant Human Thyrotropin Plus Radioactive Iodine Among Patients With Thyroid Cancer
Authors: Tan Hui , Gu Yushen , Xiu Yan , Han Xingmin , Wen Qiang , Lv Zhongwei , Fan Wei , Li Sijin , Tan Jian , Wang Feng , Fu Wei , Zhang Yifan , Xin Jun , Ouyang Wei , Wang Xuemei , Liu Bin , Chen Yue , Liu Xuegong , Mo Yi , Luo Quanyong , Wang Jing , Li Meng , Di Yan , Xu Tao , Shi Hongcheng 
Published: November 2024

ImportanceRadioactive iodine (131I or RAI) therapy has long been the standard of care for most patients with differentiated thyroid cancer (DTC) after primary surgery. However, no multicenter prospective studies have identified the optimal administered activity and stimulation method for RAI therapy in patients with intermediate-risk DTC.ObjectiveTo compare the efficacy and safety of recombinant human thyrotropin (SNA001) with thyroid hormone withdrawal (THW) plus 3.7 GBq RAI in patients with intermediate-risk DTC.Design, Setting, and ParticipantsThis noninferiority, open-label, phase 3 randomized clinical trial was conducted at 19 sites in China from April 16, 2020, to September 9, 2021, with a follow-up period of 8 months. Patients aged 18 to 70 years with DTC who had undergone a total or near-total thyroidectomy and had no distant metastasis were enrolled in the trial. Statistical analysis followed the full analysis and per-protocol analysis sets and was performed between November 18, 2021, and April 18, 2022.InterventionPatients were randomly assigned 1:1 to receive SNA001, 0.9 mg, intramuscular injection daily for 2 days or to undergo thyroid hormone withdrawal for 3 to 6 weeks.Main Outcomes and MeasuresThe primary end point was the success rate after 6 to 8 months of RAI therapy. Success was defined as a negative diagnostic whole-body scan result and a stimulated thyroglobulin level less than 1.0 ng/mL.ResultsA total of 307 patients (192 females [62.5%]; median [range] age, 40 [19-69] years) were randomized: 154 to the SNA001 group and 153 to the THW group. Baseline characteristics were evenly matched between the 2 groups. Noninferiority in the success rate of RAI therapy between groups was met, with success rates of 43.8% in the SNA001 group and 47.1% in the THW group (risk difference, −3.3; 95% CI, −14.8 to 8.3 percentage points). Forty-six patients (29.9%) in the SNA001 group reported adverse events compared with 90 (58.8%) in the THW group during RAI therapy (P &amp;lt; .001). No treatment-related adverse events leading to discontinuation and drug modification occurred in the SNA001 group.Conclusions and RelevanceThis randomized clinical trial showed that SNA001 was noninferior to THW plus 3.7 GBq RAI in patients with predominantly intermediate-risk DTC. SNA001 also demonstrated a favorable safety profile compared with THW and had a lower incidence of adverse events.Trial RegistrationChinese Clinical Trial Registry Identifier: ChiCTR2100046907
Comprehensive Enteroviral Serology Links Infection and Anti‐Melanoma Differentiation‐Associated Protein 5 Dermatomyositis
Authors: Jayaraman Sahana , Tiniakou Eleni , Morgenlander William R. , Na Miso , Christopher‐Stine Lisa , Larman H. Benjamin 
Published: November 2024

ObjectiveIdiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic autoimmune diseases characterized by specific clinical features and, frequently, skeletal muscle inflammation. Specific subtypes of IIMs can be characterized by myositis‐specific autoantibodies and are associated with distinct clinical phenotypes. Here, we focus on anti‐melanoma differentiation‐associated protein 5 (MDA5)–positive myositis and anti‐signal recognition particle (SRP)‐positive myositis, both of which exhibit seasonality but lack known environmental triggers.MethodsWe employed Phage ImmunoPrecipitation Sequencing to profile serum antibodies against the human proteome, the human virome, and a comprehensive enterovirus library. We analyzed sera from 57 patients with anti‐MDA5 autoantibodies and 57 patients with anti‐SRP autoantibodies, as well as 57 healthy controls. All groups were matched for age, sex, and race.ResultsOur autoantibody profiling results define specific immunogenic regions within the MDA5 and SRP autoantigens. We also discovered that in MDA5 sera, versus SRP sera, there was an elevated antibody response to the viral capsid protein 1 (VP1) of enterovirus B, which was accompanied by a decreased antibody response to rhinovirus A.ConclusionConsidering the role of MDA5 as a sensor of picornaviral infections and a mediator of inflammatory signaling, our data suggest a novel etiologic link between enterovirus infection and anti‐MDA5 dermatomyositis.
A Pro‐Angiogenic Immunoprotective Membrane for Cell Therapies
Authors: Wang Huifeng , Duan Chongwen , Luo Ruyue , Liu Yugang , Tong Ophelia , Demski Julia , Rivnay Jonathan , Ameer Guillermo A. 
Published: November 2024

AbstractImmunoisolation strategies that rely on porous membranes play an important role in cell transplantation therapies to protect cells from the host's immune system. These membranes must possess immunoprotective properties while facilitating the transport of nutrients and cell products to maintain the functional integrity of encapsulated cells. An easy and scalable process is described to fabricate a dual function porous polymeric membrane that shields cells against immune cell attack and promotes vascularization to address the nutritional and oxygen requirements of transplanted cells. The fabrication process results in a membrane cross‐section with a gradient of nanopores to micropores that support cell immunoisolation and interfacial vascularization requirements, respectively. The membranes demonstrate excellent cell compatibility and effectively prevent T cell transmigration without compromising glucose diffusion and oxygen permeability. In a murine subcutaneous implantation model, membranes are stable for 60 days and exhibit significantly reduced fibrous capsules, with enhanced vascularization near the membrane. These porous polymeric membranes can potentially be used as pro‐angiogenic immunoprotective membranes for cell transplantation applications where maximizing cell viability and function is of critical importance.
Interpenetrating Polymer Network Hydrogels with Tunable Viscoelasticity and Proteolytic Cleavability to Direct Stem Cells In Vitro
Authors: Seth Prannoy , Friedrichs Jens , Limasale Yanuar Dwi Putra , Fertala Nicole , Freudenberg Uwe , Zhang Yixin , Lampel Ayala , Werner Carsten 
Published: November 2024

AbstractThe dynamic nature of cellular microenvironments, regulated by the viscoelasticity and enzymatic cleavage of the extracellular matrix, remains challenging to emulate in engineered synthetic biomaterials. To address this, a novel platform of cell‐instructive hydrogels is introduced, composed of two concurrently forming interpenetrating polymer networks (IPNs). These IPNs consist of the same basic building blocks – four‐armed poly(ethylene glycol) and the sulfated glycosaminoglycan (sGAG) heparin – are cross‐linked through either chemical or physical interactions, allowing for precise and selective tuning of the hydrogel's stiffness, viscoelasticity, and proteolytic cleavability. The studies of the individual and combined effects of these parameters on stem cell behavior revealed that human mesenchymal stem cells exhibited increased spreading and Yes‐associated protein transcriptional activity in more viscoelastic and cleavable sGAG‐IPN hydrogels. Furthermore, human induced pluripotent stem cell (iPSC) cysts displayed enhanced lumen formation, growth, and pluripotency maintenance when cultured in sGAG‐IPN hydrogels with higher viscoelasticity. Inhibition studies emphasized the pivotal roles of actin dynamics and matrix metalloproteinase activity in iPSC cyst morphology, which varied with the viscoelastic properties of the hydrogels. Thus, the introduced sGAG‐IPN hydrogel platform offers a powerful methodology for exogenous stem cell fate control.
Solution Processed Bilayer Metal Halide White Light Emitting Diodes
Authors: Liu He , Shonde Tunde Blessed , Olasupo Oluwadara Joshua , Manny Tarannuma Ferdous , Islam Md Sazedul , Viera Jarek , Khizr Mohammad , Moslemi Sahel , Lin Xinsong , Winfred J.S. Raaj Vellore , Nasser Layla El , (Sam) Mao Keyou , Ma Biwu 
Published: November 2024

AbstractMetal halide perovskites and perovskite‐related organic metal halide hybrids (OMHHs) have recently emerged as a new class of luminescent materials for light emitting diodes (LEDs), owing to their unique and remarkable properties, including near‐unity photoluminescence quantum efficiencies, highly tunable emission colors, and low temperature solution processing. While substantial progress has been made in developing monochromatic LEDs with electroluminescence across blue, green, red, and near‐infrared regions, achieving highly efficient and stable white electroluminescence from a single LED remains a challenging and under‐explored area. Here, a facile approach to generating white electroluminescence is reported by combining narrow sky‐blue emission from metal halide perovskites and broadband orange/red emission from zero‐dimensional (0D) OMHHs. For the proof of concept, utilizing TPPcarz+ passivated two‐dimensional (2D) CsPbBr3 nanoplatelets (NPLs) as sky blue emitter and 0D TPPcarzSbBr4 as orange/red emitter (TPPcarz+ = triphenyl (9‐phenyl‐9H‐carbazol‐3‐yl) phosphonium), white LEDs (WLEDs) with a solution processed bilayer structure have been fabricated to exhibit a peak external quantum efficiency (EQE) of 4.8% and luminance of 1507 cd m−2 at the Commission Internationale de L'Eclairage (CIE) coordinate of (0.32, 0.35). This work opens a new pathway for creating highly efficient and stable WLEDs using metal halide perovskites and related materials.
Cr6+ Loaded Lewis Acidic Sn‐Beta Zeolites as Reusable Catalysts for Selective Production of Light Olefins via Polyolefin Cracking
Authors: Kokuryo Shinya , Tsubota Soshi , Miyake Koji , Uchida Yoshiaki , Mizusawa Atsushi , Kubo Tadashi , Nishiyama Norikazu 
Published: November 2024

AbstractCatalysts for the selective recovery of light olefins from polyolefins should be developed to save limited fossil resources. It is previously revealed that Brønsted acid‐free Sn‐Beta zeolites selectively produced light olefins from polyolefin cracking. Brønsted acid sites ionize olefins by protonation and the generated carbenium ions are converted into other hydrocarbons via various reactions, thereby the elimination of their effects led to the improvement of light olefin production ability. However, the deactivation of zeolites by coke deposition is a critical problem for industrialization. Inhibition of coking deactivation is previously achieved by doping Cr6+ species connected to silanol groups in zeolites. This work aimed to inhibit coke deposition and realize selective and continuous production of light olefins through repetitive polyolefin catalytic cracking. Sn‐Beta zeolites are prepared with various crystallinity by changing the feed fluoride ions content in their synthesis and found that their activity on low‐density polyethylene (LDPE) cracking strongly depended on the feed F/Si ratios, implying the active sites for polyolefin cracking are Lewis acidic open‐Sn sites. Moreover, Cr6+‐doped Sn‐Beta zeolites showed over 45% light olefin yields even in the third LDPE cracking test, although excess Cr adding led to reduce the catalytic activity of Sn‐Beta zeolites.
Improving Signal‐to‐Noise Ratio of 1.5T MRI Scans Using High‐Q Resonators Based on Coupled Octa‐Spirals
Authors: Gupta Jegyasu , Bhattacharjee Ratnajit , Kanagaraj Subramani , Sikdar Debabrata 
Published: November 2024

AbstractMetamaterials or metamaterial‐inspired structures/resonators have yielded significant advancement in the imaging capabilities of Magnetic Resonance Imaging (MRI) by boosting its performance parameter, i.e., signal‐to‐noise ratio (SNR). Metamaterials have a distinctive ability to boost and redistribute magnetic fields inside the subject undergoing scan when integrated as accessories between receive arrays and the subject. However, the translation of most reported metamaterials into a clinical accessory is still limited and challenging due to their low sensitivity, sub‐optimal performance, and bulky footprints for integration inside MRI scanners. Herein, a metamaterial‐inspired structure is developed using coupled octa‐spiral resonators to boost magnetic field localization inside the scanned region. In addition, the high‐Q resonance of the metamaterial‐inspired structure improves impedance matching and enhances the transmit/receive efficiency of MRI coils. Theoretical analysis of electromagnetic responses and full‐wave simulations show a homogeneous boost in SNR by over times throughout a human‐properties mimicking phantom using the resonator with a maximum SNR enhancement factor (EF) of . The spatial distribution of SNR EF inside the phantom is also validated by preliminary laboratory experiments. Thus, the developed coupled octa‐spirals resonator can pave the way for developing and adopting metamaterial‐inspired devices as clinical accessories for facilitating better, faster, and cost‐effective MRI scans.
Growth of a Tessellation: Geometric rules for the Development of Stingray Skeletal Patterns
Authors: Yang Binru , Knötel David , Ciecierska‐Holmes Jana , Wölfer Jan , Chaumel Júlia , Zaslansky Paul , Baum Daniel , Fratzl Peter , Dean Mason N. 
Published: November 2024

AbstractThe skeletons of sharks and rays, fashioned from cartilage, and armored by a veneer of mineralized tiles (tesserae) present a mathematical challenge: How can the continuous covering be maintained as the skeleton expands? This study, using microCT and custom visual data analyses of growing stingray skeletons, systematically examines tessellation patterns and morphologies of the many thousand interacting tesserae covering the hyomandibula (a skeletal element critical to feeding), over a two‐fold developmental change in hyomandibula length. The number of tesserae remains surprisingly constant, even as the hyomandibula expands isometrically, with all hyomandibulae displaying self‐similar distributions of tesserae shapes/sizes. Although the distribution of tesserae geometries largely agrees with the rules for polyhedra tiling of complex surfaces—dominated by hexagons and a minor fraction of pentagons and heptagons, but very few other polygons—the agreement with Euler's classic mathematical laws is not perfect. Contrary to the assumed uniform growth rate (which is shown would create geometric incompatibilities), larger tesserae grow faster to accommodate skeletal expansion. It is hypothesized that this local regulation of global system complexity is driven by tension (from cartilaginous core expansion) in the fibers connecting tesserae, with strain‐responsive cells orchestrating local mineral apposition.
Evaluating corn, tall fescue and canola growth on sediments dredged from the Lorain Harbor
Authors: Roddy Maureen E. , Kalhert Emily , Platt Corry T. , Julian Ashley N. , Rúa Megan A. 
Published: November 2024

AbstractSoil degradation is a worldwide problem, causing the declining performance of many plant species. Recently, the application of sediments dredged from aquatic waterways has received attention for their potential as an organic amendment to revive degraded agricultural soils. In Ohio, dredged sediment research has largely focused on the success of corn (Zea mays) or soybean (Glycine max) following the application of dredged sediments from the Toledo Harbor, neglecting the potential for dredged sediments from the other eight harbors and waterways to change plant performance as well as failing to quantify benefits for other commonly grown crops in the region. In a greenhouse experiment, we applied dredged sediments from the Lorain Harbor to degraded agricultural soils across a variety of application ratios and quantified changes in germination, height over the growing season, final biomass, and yield for canola (Brassica napus), tall fescue KY 31 (Festuca arundinacea), and corn to better understand the potential for dredged sediments from this location to increase performance for a variety of regionally important plant species. Overall, plants grown on agricultural soils supplemented with dredged sediments from the Lorain Harbor consistently grew taller, faster, and were larger than the 100% dredged sediment treatments. Furthermore, both corn and tall fescue grown on agricultural soil supplemented with dredged sediments had greater yield compared to their counterparts grown on unamended agricultural soil. In whole, outcomes from this research contribute to a growing body of research that support the use of dredged sediments as a soil amendment for agricultural soils.
Boron Enabled Directed [2+2]‐ and Dearomative [4+2]‐Cycloadditions Initiated by Energy Transfer
Authors: Adak Souvik , Hazra Partha Sarathi , Fox Carter B. , Brown M. Kevin 
Published: November 2024

AbstractA strategy for the photosensitized [2+2]‐cycloaddition between styrenyl dihaloboranes and unactivated allylamines to access cyclobutylboronates with control of stereochemistry and regiochemistry is presented. The success of the reaction relies on the temporary coordination between in situ generated dihaloboranes and amines under mild reaction conditions. In addition, cyclobutanes with varying substitution patterns have been prepared using N‐heterocycles as directing group. Manipulation of the C−B bond allows for the synthesis of a diverse class of cyclobutanes from simple precursors. Moreover, these reactions lead to the synthesis of complex amines and heteroaromatic compounds, which have significant utility in medicinal chemistry. Finally, a dearomative [4+2]‐cycloaddition of naphthalenes using a boron‐enabled temporary tethering strategy has also been uncovered to synthesize complex 3‐dimensional borylated building blocks.