bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis User Experience Aplikasi Dana Menggunakan Framework HEART Metrics
Authors: Naufal Kurniawan  , Megawati  , Syaifullah  , Eki Saputra  
Published: October 2024

Aplikasi Dana merupakan suatu layanan keuangan digital yang memberikan kemudahan kepada penggunanya. Terdapat respon negatif pada aplikasi Dana yaitu, Pengguna mengeluh bahwa untuk mengupgrade akun premium sangat sulit, dan juga terjadi kehilangan saldo secara tiba-tiba. Penelitian ini menggunakan metode HEART Metrics sebagai pengukurusan pengalaman pengguna . Penelitian ini bertujuan untuk mengetahui tingkat pengalaman pengguna aplikasi Dana berdasarkan pengalaman pengguna. Hasil dari penelitian ini menunjukkan bahwa pada variabel Happiness mendapatkan nilai sebesar 0,787 status tercapai, Engagement mendapatkan nilai 0,665 status tidak tercapai dan perlu perbaikan, Adopsi mendapatkan nilai 0,787 status tercapai, Retention mendapatkan nilai 0,742 status tercapai, Task Success mendapatkan nilai 0,756 dengan status tercapai. Perlu dilakukan perbaikan atau peningkatan terhadap variabel Engagement agar mendapatkan nilai yang lebih baik dari sebelumnya.
PENGARUH WAKTU DAN LETAK PEMANGKASAN DAUN TERHADAP PRODUKSI DAN KANDUNGAN GULA TANAMAN JAGUNG MANIS (Zea mays L. Saccharate Sturt)
Authors: Rahman A. Adlu , Haris Abdul , Sabahannur St. 
Published: October 2024

The study aims to determine the effect of leaf pruning time on the production and sugar content of sweet corn plants, analyze the effect of the location of sweet corn leaf pruning that provides the best production and sugar content, and analyze the effect of the interaction between leaf pruning time and pruning location on the production and sugar content of sweet corn plants. The study was conducted in January - March 2024 in an experimental field at the Gowa Agricultural Development Polytechnic (POLBANGTAN) Campus, Romanglopoa Village, Bontomarannu District, Gowa Regency. This study was conducted using a randomized block design (RBD) consisting of two factors. The first factor is the pruning time which consists of 3 levels: Leaf pruning at the age of 30 Day After Planting (DAP); Leaf pruning at the age of 40 DAP; and Leaf pruning at the age of 50 DAP. The second factor is the location of leaf pruning which consists of 3 levels, namely: Pruning 3 upper leaves; Pruning 3 lower leaves, and Pruning 1 upper leaf and 2 lower leaves. The results showed that pruning the three upper leaves at the age of 50 DAP produced the weight of the cob with the heaviest husk of 420.00 g and was significantly different from other treatments at the same age. The treatment between pruning at the age of 50 DAP and pruning the three upper leaves significantly affected the characteristics of sweet corn cobs, namely the diameter of the cob with the highest husk reaching 50.72 mm. The treatment of pruning at the age of 50 DAP with pruning the three upper leaves also affected the sugar content, with a brix content value reaching 15%, which was significantly different from other treatments at the same age.
PRODUKSI UBI JALAR (Ipomea batatas L.) KARENA PENGARUH KETINGGIAN BEDENGAN DAN JENIS MULSA
Authors: Kasifah Kasifah , Mado Irwan , Sam Jumrah Aspiani , Pudji Nusron Petta 
Published: October 2024

Sweet potato plants require bed height and type of mulch for good growth and production. This research aims to determine the effect of bed height and mulch type on sweet potato (Ipomoea batatas L.) production. The study used a factorial randomized block design (RBD) with 2 factors. The first factor is the treatment of bed height and the second is the mulch type. The research was analyzed using analysis of variance and continued with an honest significant difference (HSD) test which will be done using the Excel application. The research showed that bed height and partial use of mulch significantly affected tuber production in sweet potatoes. The best bed height is 30 cm. The use of silver-black plastic mulch has a significant influence on sweet potato production. The interaction between bed height and mulch type only significantly affected tuber length in sweet potatoes
Terapi Aktivitas Pada Lansia dengan Kerajinan Tangan : Pembuatan Gelang Manik - Manik
Authors: Hamdayani Hamdayani , Annisa Fauziyah , Gwijangge Kisena 
Published: October 2024

Pengabdian ini bertujuan untuk memberikan pemahaman kepada lansia tentang pentingnya terapi aktivitas dalam meningkatkan fungsi kognitif dan afektif pada lansia Dengan mengangkat Judul kegiatan : Terapi Aktivitas Pada Masa Lansia dengan kerajinan tangan . Terapi aktivitas pada lansia merupakan proses kegiatan yang melibatkan lansia dengan membuat kerajinan tangan. Terapi Aktivitas Terapi aktivitas kelompok merupakan bentuk terapi modalitas yang didasarkan pada pembelajaran hubungan interpersonal. Dengan bergabung dalam kelompok, klien dapat saling bertukar pikiran dan pengalaman dan mengembangkan pola perilaku baru (Achiryani dkk, 2005). Kerajinan tangan merupakan Kerajinan tangan, juga dikenal sebagai seni kriya atau handy craft, adalah kegiatan seni yang menitikberatkan pada keterampilan tangan untuk membuat produk atau barang yang memiliki fungsi pakai atau keindahan. Kerajinan tangan biasanya dibuat dengan cara tradisional menggunakan bahan baku yang sering ditemukan di lingkungan, bukan diproduksi oleh mesin di pabrik. Kegiatan ini juga bertujuan mengajak lansia untuk berfikir secara kreatif, melatih afektik ,kognitif, melatih fokus, meningkatkan suasana hati, kesehatan mental, menyalurkan emosi, meningkatkan interaksi sosial, dan meningkatkan produktifitas dengan membuat kerajinan tangan . dengan Metode Pelaksanaan interaktif dan demonstrasi maka kegiatan yang dilakukan Sekolah Lansia Abdie Harapan ini disambut baik oleh para lansia dengan penuh semangat dan antusias dan kegiatan ini berjalan lancar.
Upaya Peningkatan Kesehatan Immunisasi Dasar Pada Bayi Dan Balita Melalui Posyandu
Authors: Sainah Sainah Iin , Sofyan Muhammad , Rahman Abdul 
Published: October 2024

Pos Pelayanan Terpadu (Posyandu) merupakan salah satu strategi utama dalam pelayanan kesehatan primer di Indonesia, yang bertujuan untuk meningkatkan kesehatan ibu dan anak di tingkat komunitas. Posyandu menyediakan layanan berbasis masyarakat yang meliputi monitoring pertumbuhan anak, pelayanan imunisasi, penyuluhan kesehatan, dan pemeriksaan kesehatan rutin bagi ibu hamil dan balita. Pendekatan ini mendorong partisipasi aktif masyarakat dalam upaya pencegahan penyakit dan perbaikan kesehatan secara menyeluruh. Meskipun telah memberikan kontribusi signifikan dalam peningkatan cakupan layanan kesehatan dasar, tantangan yang dihadapi oleh Posyandu termasuk keterbatasan sumber daya, koordinasi antarlembaga, dan peningkatan mutu layanan. Dengan memperkuat peran kader, meningkatkan fasilitas dan dukungan, serta melibatkan masyarakat secara aktif, Posyandu dapat menjadi lebih efektif dalam mencapai tujuan pelayanan kesehatan masyarakat di Indonesia.Imunisasi merupakan upaya memberikan kekebalan pada bayi dan anak dengan memasukkan vaksin ke dalam tubuh agar tubuh membuat zat anti untuk mencegah penyakit tertentu. Menurunnya kunjungan imunisasi bayi dan balita dapat mengakibatkan meningkatnya risiko terjangkit penyakit yang dapat dicegah dengan imunisasi sehingga dikhawatirkan terjadinya kejadian luar biasa. Edukasi ini bertujuan untuk meningkatkan pengetahuan ibu yang mempunyai bayi/balita di Perumahan Green Nurhidayat Romangpolong, Posyandu Flamboyan Samata Posyandu Flamboyan Wilayah Puskesmas Samata, Kecamatan Somba Opu, Kabupaten Gowa, Sulawesi Selatan, mengenai imunisasi dasar lengkap. Metode yang digunakan yaitu penyuluhan menggunakan leaflet dan membagikannya sebagai media edukasi. Sebanyak 45 orang ibu bayi dan balita berhasil dijangkau. Sejumlah 45 leaflet berhasil dibagikan kepada ibu bayi dan balita sebagai media edukasi.
An observational study of lower limb muscle imbalance assessment and gait analysis of badminton players
Authors: Huang Ping , Xu Wenxin , Bai Zeyi , Yu Lin , Mei Qichang , Gu Yaodong 
Published: October 2024

PurposeThe imbalance of muscle strength indicators has a negative impact on players. Lower limb muscle imbalance can cause gait abnormalities and increase the risk of muscle injury or decreased performance in significantly asymmetrical situations. This study aims to assess the lower limb muscle imbalance and gait feature between the dominant and non-dominant sides of badminton players and the associations between the two variables.MethodsThe study included 15 badminton players with years of training experience. Muscle strength and gait parameters were obtained from isokinetic muscle strength testing and plantar pressure analysis systems. The symmetry index was calculated based on formulas such as plantar pressure distribution and percentage of plantar contact area.ResultsIn the isokinetic muscle strength test, significant differences were found in bilateral knee flexors’ average power and total work at 60°/s angular speed. The hamstring to quadriceps ratio (H/Q) range of knee joints of the dominant and non-dominant sides is 0.63–0.74 at low speed, while the H/Q range is 0.81–0.88 at fast speed. The H/Q of bilateral knees increases with increasing angular velocity. As the angular velocity increases, the peak torque to body weight ratio (PT/BW) of the participants’ bilateral knee flexors and extensors shows a decreasing trend. The asymmetry score of H/Q at 180°/s angular speed is positively related with step time and stance time. There are varying degrees of differences in gait staging parameters, plantar pressure in each area, plantar contact area, and symmetry index between the dominant and non-dominant sides of badminton players when walking.ConclusionBadminton players have weaker flexors of the knee joint, imbalanced muscle strength in flexors and extensors, decreased lower limb stability, and a risk of knee joint injury on the non-dominant side. The bending and stretching strength of the knee joint on the dominant side of the players is greater than that on the non-dominant side. The pressure in the first metatarsal region of the dominant side is higher, while that in the midfoot and heel regions is higher on the non-dominant side. badminton players have better forward foot force and heel cushioning ability. Long term badminton sports result in specialized changes in plantar pressure distribution and reduced symmetry.
Biocompatibility of 3D-printed vs. thermoformed and heat-cured intraoral appliances
Authors: Weżgowiec Joanna , Małysa Andrzej , Szlasa Wojciech , Kulbacka Julita , Chwiłkowska Agnieszka , Ziętek Marek , Więckiewicz Mieszko 
Published: October 2024

ObjectivesThe development of additive manufacturing has the potential to revolutionize the fabrication of medical devices. This technology, also known as 3D printing, offers precise, cost-effective, and personalized approaches, which could be particularly beneficial in the production of intraoral appliances. Despite its promise, research on the biocompatibility of 3D-printed intraoral devices is still limited. Our study aims to address this gap.MethodsWe examined the cytotoxicity of materials processed via three techniques commonly used for the fabrication of different intraoral appliances: 3D printing (Dental LT Clear), thermoforming (Duran adjusted with Durasplint LC), and conventional heat-curing (Villacryl H Plus). We also investigated the impact of chemical or UVC disinfection on the biocompatibility of these materials. We assessed the biological effects induced in human gingival fibroblasts (HGFs) through both direct contact tests (MTT and LDH assays) and extract tests (PrestoBlue, DCF, and cell death type assays). Additionally, we observed changes in cellular morphology and migration rate under an inverted light microscope. The surface roughness of materials was evaluated using contact profilometry. Statistical analysis was conducted using two-way analysis of variance.ResultsOur findings suggest that all three fabrication techniques induced a slight cytotoxic effect in HGFs, as evidenced by both direct contact and extract tests. However, these materials could be considered nontoxic according to the ISO 10993-5:2009 norm, as the decrease in metabolic activity observed was always less than 30% compared to the untreated control.ConclusionThis novel study confirms that 3D printing may be a safe alternative to conventional methods for fabricating intraoral appliances. However, further tests assessing the long-term intraoral usage are still needed.
Development and preliminary assessment of the iFIND TBR: all-in- one molecular diagnostic assay for rapid detection of Mycobacterium tuberculosis and rifampicin resistance
Authors: Ou Xichao , Song Zexuan , Xing Ruida , Zhao Bing , Pei Shaojun , Teng Chong , Zhang Lincai , Sun Qian , Liu Fang , Xia Hui , Zhou Yang , Zheng Yang , Song Yuanyuan , Zhang Zhiguo , Wang Shengfen , Anthony Richard , Zhao Yanlin 
Published: October 2024

IntroductionEarly and accurate diagnosis of tuberculosis (TB) is crucial for initiating timely treatment and preventing new infections. In this study, we introduced the iFIND TBR assay, an automated all-in-one tuberculosis detection approach that simultaneously detect Mycobacterium tuberculosis (MTB) and rifampicin (RIF) resistance.MethodsThe limits of detection (LOD), sensitivity, specificity, and RIF-R rpoB mutation detection of the iFIND TBR were tested on Mycobacterium tuberculosis DNA or sputum samples spiked with known numbers of M.tuberculosis H37Rv. Frozen clinical samples from patients suspected of having TB were also tested.ResultsThe LOD of the iFIND TBR for MTB detection were 13.34 CFU/ml (95% CI, 11.71-16.47), and for RIF resistance was 109.79CFU/mL (95% CI, 95-138.19). The iFIND TBR assay accurately distinguish MTB strains from non-tuberculous mycobacteria (NTM) without any cross reactivity. Testing on 157 clinical sputum samples, compared with the bacteriologically TB standard, the overall sensitivity and specificity of the iFIND TBR was 100% (95%CI, 94.64, 100) and 85.29% (95% CI, 74.61, 92.72), respectively. When assessing RIF susceptibility, the iFIND TBR achieved a sensitivity of 98.15% (95% CI, 90.11–99.95) and a specificity of 85.71% (95% CI, 67.33–95.97), compared with phenotypic drug susceptibility testing. Discordant RIF susceptibility results were more frequently observed in samples exhibiting heteroresistance.DiscussionThese findings demonstrate that iFIND TBR assay performs well in detecting TB and RIF resistance, and shows promise as a point-of-care tool in resource-limited areas.
Metabolomics revealed pharmacodynamic effects of aspirin and indobufen in patients after percutaneous transluminal angioplasty surgery
Authors: Sun Shaobo , Xun Kang , Li Damei , Bao Renjie 
Published: October 2024

IntroductionAspirin and indobufen are commonly used therapeutic drugs for the prevention of vascular restenosis (VR) after percutaneous transluminal angioplasty surgery. They both exhibited antiplatelet effects but molecular mechanisms underlying metabolic changes induced by them remain unclear.MethodsIn this study, we collected plasma samples from patients on aspirin medication (n = 5), patients on indobufen medication, patients with no medication after PTA, and healthy controls (CKs) (n = 5). Our investigation aimed to reveal the metabolic processes in patients during vascular restenosis and its amelioration through drug therapy using liquid chromatography-tandem mass spectrometry (LC-MS/MS).ResultsOur data showed significant alterations in amino acid and choline metabolism in patients without medication after PTA. Aspirin and indobufen were able to regulate these metabolic pathways to alleviate VR symptoms. We identified several characteristic amino acids, including pro-leu, L-citrulline, his-glu, and L-glutamate, as important biomarkers for VR assessment in patients without medication after PTA. A total of 17 and 4 metabolites involved in arginine and phenylalanine metabolism were specifically induced by aspirin and indobufen, respectively. Their expression levels were significantly regulated by aspirin or indobufen, nearly reaching normal levels.DiscussionTaken together, our identification of metabolites involved in metabolic changes affected by aspirin and indobufen medication enhances the understanding of VR pathology after PTA. This may help identify early diagnostic biomarkers and therapeutic targets
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus
Authors: Khalid Sidra , Bashir Shahid , Mehboob Riffat , Anwar Tehreem , Ali Muhammad , Hashim Mariam , Waseem Humaira , Basharat Shahnai 
Published: October 2024

ObjectivesDiabetes mellitus is a metabolic condition with hyperglycemia. Literature has shown a correlation between poor sleep quality and duration with an increased incidence of insomnia in diabetic individuals. The goal of this study was to determine the magnesium and potassium supplementation effect among diabetic individuals with insomnia.MethodsA randomized controlled trial (single blind) was conducted on 320 patients with diabetes; after 2 months of follow-up, 290 patients completed the trial. The Insomnia Severity Index (ISI) was used to assess the severity and duration of insomnia, before and after the trial. Tablets containing supplements were prepared: placebo (T1), magnesium (Mg, T2), potassium (K, T3), and a combination of Mg and K (T4). Melatonin and cortisol (sleep hormones) were measured from blood (serum) using an enzyme-linked immunosorbent assay (ELISA), before and after the trial.ResultsThe study included 93 (32.1%) male and 197 (67.9%) female participants. According to the analysis, there was a significant association between the treatment groups and ISI after the trial (post-trial), p = 0.0001. Analysis showed that there was significant association between pre- and post-serum cortisol levels in treatment groups 2, 3, and 4 (T2, T3, and T4) as p-values are 0.001, 0.001, and 0.001 respectively. Similar findings were observed for serum melatonin.ConclusionsThe study revealed that magnesium, potassium, and magnesium and potassium combined had a significant effect on serum cortisol and melatonin levels (sleep hormones). In addition, supplementation significantly decreased the severity of insomnia among patients with diabetes by improving sleep duration.
The association of the perioperative neutrophil-to-lymphocyte ratio with wound healing in patients with Wagner grade 3 and 4 diabetic foot ulcers after tibial cortex transverse transport surgery: a prospective observational cohort study
Authors: Zhao Sichun , Guo Fudie , Zang Yonghui , Hu Rong , Yu Xianjun , Zhang Hongmei , Xie Tingting , Li Xiaoya , Bai Chunxia , Shi Haoran , Zhang Dingwei 
Published: October 2024

BackgroundDiabetic foot ulcers (DFUs) are severe complications of diabetes, involving multiple etiological factors including neuropathy, vascular insufficiency, and impaired wound healing. The global burden of DFUs is substantial, with significant morbidity and high management costs. Recent advancements have introduced the tibial cortex transverse transport (TTT) technique, which has shown promising results in the management of severe DFUs by promoting angiogenesis and immunomodulation.MethodsThis prospective cohort study enrolled patients with Wagner grade 3 and 4 DFUs, treated using the TTT technique from May 2022 to September 2023 at MianYang Central Hospital. The study assessed the influence of TTT on the perioperative neutrophil-to-lymphocyte ratio (NLR), an established biomarker of systemic inflammation, and its correlation with wound healing outcomes.ResultsA total of 82 patients were enrolled, with 66 completing the study. The survival analysis revealed that patients with a lower preoperative NLR experienced significantly faster wound healing compared with a high NLR (log rank test P&lt; 0.05; hazard ratio (HR) = 0.46; 95% CI: 0.26–0.83). The optimal NLR cutoff values (4.25) were established to predict wound healing times for DFUs. The median NLR was significantly different before TTT surgery, 3 days after TTT surgery, and 1 month after TTT surgery (P&lt;0.05).ConclusionThe TTT technique significantly influences the perioperative NLR and is associated with improved wound healing in DFU patients. The perioperative NLR serves as an effective predictive biomarker for wound healing outcomes, highlighting the significance of interventions targeting NLR values in perioperative management strategies and postoperative monitoring protocols for the treatment of diabetic foot ulcers (DFUs) in clinical practice.
Association of triglyceride-glucose index, low and high-density lipoprotein cholesterol with all-cause and cardiovascular disease mortality in generally Chinese elderly: a retrospective cohort study
Authors: Su Donghai , An Zhantian , Chen Liyuan , Chen Xuejiao , Wu Wencan , Cui Yufang , Cheng Yulin , Shi Songhe 
Published: October 2024

BackgroundThe impact of baseline triglyceride-glucose (TyG) index and abnormal low or high-density lipoprotein cholesterol (LDL-C or HDL-C) levels on all-cause and cardiovascular disease (CVD) mortality remains unclear. This study aimed to investigate the relationship between TyG index and LDL-C or HDL-C and all-cause and CVD mortality.MethodsThis retrospective cohort study analyzed data from health examinations of 69,068 older adults aged ≥60 in Xinzheng City, Henan Province, China, between January 2013 and January 2023. Cox proportional risk regression models were used to estimate the hazard ratio (HR) and 95% confidence interval (CI) of the TyG index and LDL-C or HDL-C about all-cause and CVD mortality. Restricted cubic spline was used to assess the dose-response relationship.ResultsDuring 400,094 person-years of follow-up (median follow-up 5.8 years [interquartile range 3.0-9.12]), 13,664 deaths were recorded, of which 7,045 were due to CVD. Compared with participants in the second quartile of the TyG index, participants in the fourth quartile had a 16% increased risk of all-cause mortality (HR: 1.16, 95% CI: 1.12,1.22), and an 8% increased risk of CVD mortality (HR: 1.08, 95% CI: 1.01,1.16). Similar results were observed in LDL-C and HDL-C, with all-cause and CVD mortality risks for participants in the fourth quartile compared with participants in the third quartile for LDL-C of (HR: 1.07, 95% CI: 1.02,1.12) and (HR: 1.09, 95% CI: 1.01,1.17), respectively. The risk of all-cause and CVD mortality in participants in the fourth quartile group compared with those in the second HDL-C quartile group was (HR: 1.10, 95% CI: 1.05,1.16) and (HR: 1.11, 95% CI: 1.04,1.18), respectively. We found that the TyG index was nonlinearly associated with all-cause and CVD mortality (P non-linear &lt;0.05), and LDL-C was nonlinearly associated with all-cause mortality (P non-linear &lt;0.05) but linearly associated with CVD mortality (P non-linear &gt;0.05). HDL-C, on the other hand, was in contrast to LDL-C, which showed a non-linear association with CVD mortality. We did not observe a significant interaction between TyG index and LDL-C or HDL-C (P &gt;0.05).ConclusionTyG index and LDL-C or HDL-C increased the risk of all-cause and CVD mortality, especially a high TyG index combined with abnormal LDL-C.