bluuebunny/crossref_metadata_2025_split huggingface dataset:
Which Sternotomy Closure Method (Orthopaedic Wire or Suture) Is Recommended in Large Breed Dogs Undergoing a Median Sternotomy?
Authors: Howes Charlotte , Chanoit Guillaume 
Published: May 2018

<strong>PICO question</strong><br /><p>Which sternotomy closure method (orthopaedic wire or suture) is recommended in large breed dogs undergoing a median sternotomy?</p><strong>Clinical bottom line</strong><br /><p>The literature search revealed no clinical studies on large breed dogs comparing the clinical outcomes following either orthopaedic wire or suture sternotomy closure methods. Post-mortem studies on large breed dogs suggest that sutures are as suitable as orthopaedic wires for sternal closure with regards to their biomechanical properties. There is insufficient clinical evidence to make a recommendation that sutures be used in large breeds of dog.</p><br /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access" /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/pr-icon.jpg" alt="Peer Reviewed" />
Use of Intravenous Lipid Emulsion in Dogs With Suspected Tremorgenic Mycotoxicosis: 53 Cases
Authors: Kormpou Foteini , O’Sullivan Aoife , Troth Laura , Adamantos Sophie 
Published: May 2018

<strong>Abstract</strong><p><strong>Objective: </strong>The purpose of this study is to report the use of intravenous lipid emulsion (ILE) in dogs presenting with suspected tremorgenic mycotoxicosis based on signs of intoxication and known ingestion of mouldy food or compost.</p><p><strong>Background: </strong>ILE is being used for toxicoses associated with fat soluble agents. As tremorgenic mycotoxins are lipophilic in nature, the use of ILE may be of benefit in these patients. </p><p><strong>Methods: </strong>Medical records of all dogs examined at any Vets Now clinic between November 2012 and November 2016, in which ILE had been used, were reviewed and 53 cases were included in the study.</p><p><strong>Results: </strong>In 96% of cases there was clinical improvement recorded post ILE administration within a median time of 4 hours. No adverse effects were seen during the infusion or up to the time of discharge.</p><p><strong>Conclusion: </strong>The administration of ILE seems to be associated with a beneficial effect in the short term in dogs. Prospective evaluation of this therapy is warranted to further evaluate the use of ILE in these cases.</p><a href="https://ctt.ac/UQ947" target="_blank"><img style="border: 0px none; width: 79px; height: 33px; margin: 0px; float: left; outline: none; text-decoration: none; -ms-interpolation-mode: bicubic;" src="https://gallery.mailchimp.com/d225a799e9a6edf193d7484f0/images/e989acbf-a9e8-41d9-ade3-1c24637fcbdd.png" alt="" width="79" height="33" data-file-id="2781617" /></a><br /><br /><img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access" /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/pr-icon.jpg" alt="Peer Reviewed" />
Agudeza visual de Snellen versus frecuencia espacial del test de mirada preferencial
Authors: Merchán Price María Susana , Acosta Yepes Nelson Fernando , Gonzales Rodríguez Mayra Liliana , Cortés Rodríguez Diana Catalina 
Published: May 2018

La agudeza visual medida con la cartilla de Snellen y el test de mirada preferencial son utilizados para determinar cuantitativamente la capacidad que tiene el sistema visual para discriminar los detalles desde temprana edad hasta la adultez. Aunque matemáticamente los ciclos por grado del test de mirada preferencial y la fracción Snellen sean comparables, también se deben tener en cuenta otros factores propios de la persona como los perceptuales y del desarrollo de las estructuras oculares del individuo, así como otros correspondientes a factores físico-ambientales donde se realizan los test, tal como la iluminación.
Determinación del tiempo de recobro al fotoestrés mediante el test de deslumbramiento en pacientes diabéticos tipo II y pacientes sanos
Authors: Caicedo Azuero Anny Johana , Aguilar Casas Patricia 
Published: May 2018

Objetivo: determinar los cambios en el tiempo de recobro al fotoestrés mediante el test de deslumbramiento en pacientes diabéticos tipo II, con más de cinco años de diagnóstico y pacientes sanos. Metodología: se examinaron 100 pacientes, divididos en dos grupos, cada uno de 50 sujetos: uno de pacientes diabéticos tipo II y el otro de sanos. Se realizaron test de glucometría, toma de agudeza visual, oftalmoscopía y test de deslumbramiento, previa estandarización de las pruebas se recolectó la información en ópticas y brigadas de salud en la ciudad de Bogotá. Resultados: el tiempo promedio de recuperación al fotoestrés en pacientes diabéticos tipo II fue de 33,57 segundos, mientras que, para los pacientes sanos, fue de 24,09 segundos. Los valores del tiempo de recuperación al fotoestrés estuvieron dentro del rango y el límite de la normalidad, de 15 a 35 segundos. Hubo diferencias significativas (p = 0,02565) en el tiempo promedio de recobro al fotoestrés entre los géneros masculino y femenino de la población sana y diabética. Los pacientes diabéticos presentaron un tiempo de recuperación mayor, entre 8,33 y 11,33 segundos, que los sujetos sanos. Conclusiones: los pacientes diabéticos no tienen alteraciones en el tiempo de recobro al fotoestrés, sin embargo, este tiempo fue mayor significativamente, que el de los sujetos sanos en este estudio.
Cinco sentidos de semántica
Authors: Eco Umberto 
Published: May 2018

El semiólogo y escritor italiano Umberto Eco (1932-2016) problematiza la noción de semántica, entendida de manera limitada como “el estudio del significado de las palabras”. Eco parte de cinco concepciones de la semántica, que pertenecen a diversas escuelas de la lingüística, la filosofía de lenguaje, la teoría literaria y la lexicografía para poner de manifiesto la complejidad del término y, por tanto, la idea de sentido.
Imaginar, pese a todo: problemas y polémicas en torno a la representación del Holocausto, de Shoah a El hijo de Saúl
Authors: Feldman Ilana 
Published: May 2018

Este artículo intenta investigar la polémica y los problemas en torno a la representación del Holocuasto (Shoah), a partir de tres ensayos de Georges Didi-Huberman, Images malgré tout (2003), Écorces (2011) y Sortir du noir (2015). Estos textos dialogan con lo inimaginable y lo irrepresentable, filosófica y estéticamente, y lo refutan, por medio del análisis de cuatro fotografias capturadas por miembros del Sonderkommando en Auschwitz-Birkenau en agosto de 1944. En comparación con el cine, desde Shoah a El hijo de Saúl, pasando por Noche y niebla y Kapo, actualizamos la querella de las imágenes, cada vez más actual y lejos de haber terminado.
Collette’s Lost Pet by I. Arsenault
Authors: Nugent Samantha 
Published: May 2018

Arsenault, Isabelle. Collette’s Lost Pet. Tundra Books, 2017.In this attractive, graphic novel-style picture book, Canadian author and illustrator Isabelle Arsenault tells the story of Collette—the new girl at Mile End. Unsure of how to meet other children in her new neighbourhood, Collette invents a story about a lost bird. As more children are recruited to help search for Collette’s lost bird, the fib grows, too. Although children and adults of all ages will enjoy this book’s delightful illustrations, the text is best suited to more mature readers within and above the publisher-recommended age range of 4 to 8 years. Since many younger children are taught to always speak truthfully, this book is more suitable for older readers who can reflect critically on a white lie that is not punished, but instead elicits empathy and kindness. Additionally, much of the story is told through Arsenault’s illustrations, which invite readers to find meaning beyond the words on the page. However, this nuanced relationship between text and illustrations is balanced by familiar picture book conventions, such as the repetition of phrases.Collette’s Lost Pet explores the relatable themes of being new and trying to fit in, and the protagonist’s fanciful invention of an increasingly larger-than-life parakeet makes this book’s text as engaging as its illustrations. This story demonstrates the importance of welcoming newcomers and is sure to be an appreciated addition to school, public, and home library collections.Highly Recommended: 4 out of 4 starsReviewer: Samantha NugentSam works as a librarian at the Hinton Municipal Library.
História do Esporte
Authors: Funari Pedro Paulo A. 
Published: May 2018

O historiador Thierry Terret, professor da Universidade de Lyon, França, é um grande especialista na trajetória do esporte, com mais de vinte livros publicados sobre o tema, desde 1993. Terret mostra, neste volume introdutório, as transformações do esporte, desde sua invenção no século XVIII, na Inglaterra, na esteira da revolução industrial e preocupa-se, ainda, em tratar dos debates historiográficos, em particular no último meio século de pesquisas.
Professores de uma escola pública paulista analisam o Exame Nacional do Ensino Médio (ENEM)
Authors: Piunti Juliana Cristina Perlotti , Anunciato Rosa Maria Moraes 
Published: May 2018

O ensino médio está em evidência nas atuais discussões políticas sobre educação no Brasil. A reforma que altera significativamente a LDB 9.394/96 coloca em debate as reais e conflitivas demandas dessa etapa de ensino. Em momento paralelo à polêmica da Lei de Reforma do Ensino Médio, tornaram-se públicas as notas do Exame Nacional do Ensino Médio (ENEM), gerando novas discussões na sociedade. Procuramos contribuir para esse debate sobre o ensino médio buscando compreender a perspectiva de professores sobre as repercussões do Exame Nacional do Ensino Médio na sua prática profissional. A análise dos dados de entrevistas com professores de uma escola pública estadual paulista revela que eles consideram que as mudanças constantes no plano curricular prejudicam o ensino médio e dificultam a definição de sua identidade. A partir da literatura sobre política educacional e estudos sobre a docência, aponta-se que os participantes dão novo significado às políticas educacionais no contexto em que as vivenciam como docentes e, assim, evidenciam as contradições no processo de busca por uma identidade para o ensino médio e para a mudança nas práticas docentes.
The Emerging Roles of the HERC Ubiquitin Ligases in Cancer
Authors: Mao Xinliang , Sethi Gautam , Zhang Zubin , Wang Qi 
Published: May 2018

Background:
The HERC family contains six members from HERC1 to HERC6 that are featured with
the HECT domains that exerts ubiquitin ligase activity and the RCC1-like domains that are involved in cell cycle
regulation. Although identified as early as 1990s, their biological functions are extensively studied in recent
years. More and more researches have demonstrated that the HERC ubiquitin ligases are widely engaged in carcinogenesis,
however, there lacks a comprehensive and instructive analysis.

Methods:
The PubMed database was searched by keywords of individual HERC proteins (such as HERC4) and
cancer. The emerging roles of HERC proteins in cancer and the specific mechanisms were collectively analyzed
and discussed.

Results:
HERC proteins belong to the HECT domain-containing ubiquitin ligases that can identify and mediate
the ubiquitination of specific substrate proteins. All HERC ubiquitin ligases except HERC6 have been assigned
one or more than one ubiquitination substrates. In all of HERCs, HERC1 and HERC2 have been widely studied,
in contrast, there are no reported studies yet on protein ubiquitination mediated by HERC6. Dependent on the
protein substrates, HERC proteins may act as a tumor suppressor or oncoprotein in specific cancer types. For
example, HERC4 is believed to contribute to carcinogenesis of solid tumors such as lung cancer, but it suppresses
the proliferation of myeloma cells.

Conclusion:
HERC proteins as ubiquitin ligases are widely involved in various cancers. Targeting at specific
HERC proteins could be a strategy for the treatment of certain cancers.
Effect of Steel Fiber Ratios on Behavior of High Strength Hybrid Reinforced Concrete Deep Beams under Repeated Loading
Authors: Hassan Sawsan Akram , Mhebs Ansam Hassan 
Published: May 2018

Introduction:
The present work presents experimental and analytical investigation of the effect of steel fiber ratio of behavior of high strength hybrid reinforced concrete deep beams under monotonic and repeated two point load.

Methods:
The experimental work included casting and testing of six deep beams, three of which were tested under monotonic loading (control beams) and other beams were tested under repeated loading at level of 75% of ultimate load of control beams. The effect of different SF ratios (0%,1% and 2%) with constant amount of web reinforcement (pw) were studied in terms of crack patterns, ultimate load and load versus mid span deflection.

Results and Conclusion:
From the experimental test results, it was observed the percentage increase ultimate load for hybrid beam cast with SF ratio 1% is 9.62% as compared with hybrid beam with SF ratio 0%. Also, the ultimate load for hybrid beam cast with SF ratio 2% is 28.85% as compared with hybrid beam with SF ratio 0% and 17.54% as compared with hybrid beam with SF ratio 1% under monotonic loading. Strut and Tie Model (STM) procedures were used to analyze the experimentally tested hybrid deep beams under monotonic loading of the present investigation.
Perceived Attitudes About Substance Use in Anonymous Social Media Posts Near College Campuses: Observational Study
Authors: Hammond Alexis S , Paul Michael J , Hobelmann Joseph , Koratana Animesh R , Dredze Mark , Chisolm Margaret S 
Published: May 2018

Background
Substance use is a major issue for adolescents and young adults, particularly college students. With the importance of peer influence and the ubiquitous use of social media among these age groups, it is important to assess what is discussed on various social media sites regarding substance use. One particular mobile app (Yik Yak) allowed users to post any message anonymously to nearby persons, often in areas with close proximity to major colleges and universities.

Objective
This study describes the content, including attitude toward substances, of social media discussions that occurred near college campuses and involved substances.

Methods
A total of 493 posts about drugs and alcohol on Yik Yak were reviewed and coded for their content, as well as the poster’s attitude toward the substance(s) mentioned.

Results
Alcohol (226/493, 45.8%), marijuana (206/493, 41.8%), and tobacco (67/493, 13%) were the most frequently mentioned substances. Posts about use (442/493) were generally positive toward the substance mentioned (262/442, 59.3%), unless the post was about abstinence from the substance. Additionally, posts that commented on the substance use of others tended to be less positive (18/92, 19.6% positive) compared to posts about one’s own use (132/202, 65.3% positive).

Conclusions
This study provides a description of anonymous discussions on or near college campuses about drugs and alcohol, which serves as an example of data that can be examined from social media sites for further research and prevention campaigns.
Examining the Effects of Mindful Eating Training on Adherence to a Carbohydrate-Restricted Diet in Patients With Type 2 Diabetes (the DELISH Study): Protocol for a Randomized Controlled Trial (Preprint)
Authors: Mason Ashley E , Saslow Laura , Moran Patricia J , Kim Sarah , Abousleiman Hiba , Hartman Alison , Richler Robert , Schleicher Samantha , Hartogensis Wendy , Epel Elissa S , Hecht Frederick 
Published: May 2018

BACKGROUND

Diet patterns have a profound influence on glycemic control for individuals with type 2 diabetes mellitus (T2DM), and craving-related eating is an important obstacle to dietary adherence. A growing body of research suggests that carbohydrate-restricted (CR) diets can improve glycemic control and reduce medication dependence in T2DM. However, limited data speak to the effects of long-term adherence to CR diets. Mindful eating training has been shown to reduce craving-related eating in overweight populations but has yet to be examined as a behavioral support for dietary adherence in T2DM. This trial examines behavioral mechanisms, particularly craving-related eating, through which mindful eating training might improve adherence to CR dietary recommendations in T2DM. This will clarify the importance of focusing on craving-related eating in the optimization of dietary adherence interventions.

OBJECTIVE

The aim of this trial is to determine whether providing training in mindful eating increases adherence to a CR dietary recommendation in T2DM.

METHODS

We are randomizing 60 participants to receive a CR diet with or without mindful eating training (12-week group intervention) and are following participants for 12 weeks after intervention completion. We hypothesize that participants who receive mindful eating training (relative to those who do not) will demonstrate greater adherence to the CR diet.

RESULTS

Our primary outcome is change in craving-related eating, as assessed using an ecological momentary assessment mobile phone–based platform. Secondary behavioral pathway outcomes include changes in stress-related eating, impulsivity, glycemic control, weight change, dietary adherence, and resumption of dietary adherence after dietary nonadherence.

CONCLUSIONS

This theory-driven trial will shed light on the impact of mindfulness training on mechanisms that may impact dietary adherence in T2DM.

CLINICALTRIAL

ClinicalTrials.gov NCT03207711; https://clinicaltrials.gov/ct2/show/NCT03207711 (Archived by WebCite at http://www.webcitation.org/73pXscwaU)

INTERNATIONAL REGISTERED REPOR

DERR1-10.2196/11002
Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
Authors: Luukkonen Panu K. , Sädevirta Sanja , Zhou You , Kayser Brandon , Ali Ashfaq , Ahonen Linda , Lallukka Susanna , Pelloux Véronique , Gaggini Melania , Jian Ching , Hakkarainen Antti , Lundbom Nina , Gylling Helena , Salonen Anne , Orešič Matej , Hyötyläinen Tuulia , Orho-Melander Marju , Rissanen Aila , Gastaldelli Amalia , Clément Karine , Hodson Leanne , Yki-Järvinen Hannele 
Published: May 2018

OBJECTIVE
Nonalcoholic fatty liver disease (i.e., increased intrahepatic triglyceride [IHTG] content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue lipolysis and hepatic de novo lipogenesis (DNL) are the main pathways contributing to IHTG. We hypothesized that dietary macronutrient composition influences the pathways, mediators, and magnitude of weight gain-induced changes in IHTG.

RESEARCH DESIGN AND METHODS
We overfed 38 overweight subjects (age 48 ± 2 years, BMI 31 ± 1 kg/m2, liver fat 4.7 ± 0.9%) 1,000 extra kcal/day of saturated (SAT) or unsaturated (UNSAT) fat or simple sugars (CARB) for 3 weeks. We measured IHTG (1H-MRS), pathways contributing to IHTG (lipolysis ([2H5]glycerol) and DNL (2H2O) basally and during euglycemic hyperinsulinemia), insulin resistance, endotoxemia, plasma ceramides, and adipose tissue gene expression at 0 and 3 weeks.

RESULTS
Overfeeding SAT increased IHTG more (+55%) than UNSAT (+15%, P &lt; 0.05). CARB increased IHTG (+33%) by stimulating DNL (+98%). SAT significantly increased while UNSAT decreased lipolysis. SAT induced insulin resistance and endotoxemia and significantly increased multiple plasma ceramides. The diets had distinct effects on adipose tissue gene expression.

CONCLUSIONS
Macronutrient composition of excess energy influences pathways of IHTG: CARB increases DNL, while SAT increases and UNSAT decreases lipolysis. SAT induced the greatest increase in IHTG, insulin resistance, and harmful ceramides. Decreased intakes of SAT could be beneficial in reducing IHTG and the associated risk of diabetes.
Histopathological and morphological alterations in salivary gland of House fly induced by oral administration Thiamethoxam.
Authors: Xider Karim Mohammed 
Published: May 2018

The current work the effect of Actara insecticide belongs to chemical family Neonicotinoid. The active component of thiamethoxam in three concentrations: 0.750 ppm, 1.5 ppm and 2.25ppm on adult house fly salivary glands. Histopathological and morphological effects revealed important alterations produced by this insecticide in histological and morphology of the adult house fly gland tissue categorized by increasing gland duct lumen diameter. These alterations are possibly related with excretion function of salivary gland might be accountable for removing this insecticide. Results show thiamethoxam is a powerful insecticide that performances histologically in salivary glant tissue, triggering alterations in the glands form, cytoplasm with extreme vacuolation ,disruption cell membrane, obvious disorganization tissues cells, terminating in progressive deteriorating phase with changes in nucleus glandular cell's, such alterations occurred together in its size and form of gland, disintegration of nucleus, and presence of apoptosis(fragmentation) nucleus, accelerating the process of glandular degeneration ,and interfering with feeding process of house fly particularly when the peak concentration of insecticide was used.
Regulation of housing quality in Ireland: What can be learned from food safety?
Authors: Fhloinn Deirdre Ní 
Published: May 2018

Abstract
This paper contrasts, and critically evaluates, the Irish regulatory regimes for building control and food safety. It concludes that the systems are similar in design, but vary greatly in implementation, drawing on analysis of enforcement statistics published by the Food Safety Authority of Ireland and obtained from building control authorities. It is argued that regulatory systems require enforcement and oversight in order to verify consistency of decisionmaking, compliance with their own rules and standards, and overall effectiveness, and that this lack of emphasis on enforcement and oversight is a significant failing in the Irish building control system.
Stimulated Growth of Green Algae Haematococcus Pluvialis Under Different Environmental Conditions
Authors: Minasyan Arevik 
Published: May 2018

Abstract
Haematococcus pluvialis is a genus of green algae that keeps the high interest of the scientists for decades due to its capacity to synthesize astaxanthin. Among many others, astaxanthin is one of the most demanded natural anti-oxidant and the product of the future. It has the widest usage as source of nutrient rich food and health promoting compounds. Astaxanthin has got various applications in the nutraceuticals as immune system enhancer and anti-cancer agent, in the cosmetics as anti-aging component, as additive to food, as well as in the aquaculture industries. As a key requirement for the research in this field is to find out the better conditions and media to stimulate the H.pluvialis higher growth rate to reach in the field of microalgae economically sustainable cultivation and processing. The effect of WC versus BG-11 media to enhance growth rate of Haematococcus pluvialis has been examined. This study employed a parallel testing of stimulating effect of extra vitamins versus phosphorus. Combination of mentioned parameters with gentle shacking have been determined as multiple effectors that contribute to green algae cultures to grow to high density. Importantly, this study demonstrates that extra phosphorus contribute to growth rate of H.pluvilais positively, meanwhile addition of extra vitamins in combination with extra phosphorus impact both positively and negatively to promote cells division. Shacking influences the culture growth as either stimulator or repressor.
On Almost Complete Caps in PG(N, q)
Authors: Davydov Alexander A. , Marcugini Stefano , Pambianco Fernanda 
Published: May 2018

Abstract
We propose the concepts of almost complete subset of an elliptic quadric in the projective space PG(3, q) and of almost complete cap in the space PG(N, q), N ≥ 3, as generalizations of the concepts of almost complete subset of a conic and of almost complete arc in PG(2, q). Upper bounds of the smallest size of the introduced geometrical objects are obtained by probabilistic and algorithmic methods.