bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conformations and Structures of N,N’-Bis(2-methoxybenzylidene)- 1,3-diamino-propanol and N,N’-Bis(3-methoxybenzylidene)-1,3- diamino-propanol
Authors: Kabak Mehmet , Elmali Ayhan , Elerman Yalçin , Svoboda Ingrid 
Published: August 2018

Abstract
N,N’-bis(2-methoxybenzylidene)-1,3-diamino-propanol (C19H22N2O4) 1 and N,N’-bis(3-methoxybenzylidene)- 1,3-diamino-propanol (C19H22N2O4) 2 have been investigated by X-ray analysis and AM1 semi-empirical quantum mechanical method. 1 is in the monoclinic space group C2/c with a = 33.694(6), b = 6.735(1), c = 17.681(3) Å , β = 114.72(2)°, V = 3645(1) Å3, Z = 8, Dc = 1.248 mg cm−3 and μ(Mo-Kα ) = 0.088 mm−1. 2 is in the monoclinic space group C2/c with a = 19.173(4), b = 7.626(2), c = 11.788(2) Å , β = 91.72(2)°, V = 1722.8(6) Å3, Z = 4, Dc = 1.320 mg cm−3 and μ(Mo-Kα ) = 0.093 mm−1. The crystal structures of 1 and 2 were solved by direct methods and refined to R = 0.053 for 1 and R = 0.041 for 2. Both molecules are not planar and 2 has twofold axes on C9 atom. Intramolecular hydrogen bonds occur between O1 and N1 [2.541(3) Å ] and between O3 and N2 [2.573(4) Å ] atoms for 1 and between O1 and N1 [2.631(2) Å ] atoms for 2. The optimized geometries of the crystal structures of 1 and 2 corresponding to non-planar conformation are the most stable conformation in all calculations. The results strongly indicate that the minimum energy conformation is primarily determined by non-bonded hydrogen-hydrogen and hydrogen-carbon repulsions.
A Study of Substituent Effect on the Oxidative Strengths of N-Chloroarenesulphonamides: Kinetics of Oxidation of Leucine and Isoleucine in Aqueous Acid Medium
Authors: Shetty Mahesha , Gowda B. Thimme 
Published: August 2018

Abstract
To study the variation of oxidative strengths of N-chloro-arenesulphonamides with substitution in the benzene ring, six mono- and five di-substituted N-chloro-arenesulphonamides are employed as oxidants for studying the kinetics of oxidation of two neutral amino acids, L-leucine and Lisoleucine in aqueous acid medium. The N-chloro-arenesulphonamides studied are of the constitution: ArSO2NaNCl·H2O (where Ar = C6H5, 4-CH3C6H4, 4-C2H5C6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 2,3-(CH3)2C6H3, 2,4-(CH3)2C6H3, 2-CH3-4-ClC6H3, 2,4-Cl2C6H3, and 3,4-Cl2C6H3). The reactions show second order kinetics in [oxidant], fractional order in [amino acid] and inverse dependence on [H+]. Addition of the reduced product of the oxidants or variation in ionic strength of the medium has no significant effect on the rates of oxidations. A two-pathway mechanism is considered to explain the experimental results. Effective oxidizing species of the oxidants is Cl+ in different forms. Therefore the oxidising strengths of N-chloro-arenesulphonamides depend on the ease with which Cl+ is released from them. The study reveals that the introduction of substituent in the benzene ring of the oxidant affects both the kinetic and thermodynamic data for the oxidations The electron releasing groups such as CH3 generally inhibit the rates, while electron-withdrawing groups such as Cl enhance this ability, as the electron withdrawing groups ease the release of Cl+ from the reagents and hence increase the oxidising strengths. The on Ea and logA and validity of the Hammett and isokinetic relationships for the oxidations are also analysed.
Boron Trifluoride Mediated Addition of Nucleophiles to endo- and exo-Substituted Norbornene Derivatives
Authors: İşleyen Alper , Sayraç Tuğmac , Doğan Özdemir 
Published: August 2018

Abstract
Remote substituent effects on the regioselectivity and stereoselectivity in the boron trifluoride mediated addition of nucleophiles (iodide and bromide) to endo- and exo-2-substituted norbornene derivatives have been investigated. The main products of the reactions resulted from the regioselective addition of nucleophiles to the double bond of norbornene derivatives. Products resulting from the Wagner-Meerwein type rearrangement were also isolated in considerable amounts. All of the reactions gave the addition products in reasonably good yields with high regioselectivity. The endo/exo selectivity, on the other hand, changed depending on the nucleophile and the substrate.
1,4,5,8-Tetraazafulvalene – Darstellung schwefelhaltiger Derivate und Zuordnung des Chromophors / 1,4,5,8-Tetraazafulvalenes – Synthesis of Sulfur-Containing Derivatives and Classification of the Chromophor
Authors: Kühn Christiane , Beckert R. , Grummt U.-W. , Käpplinger C. , Birckner E. 
Published: August 2018

Abstract
In order to obtain sulfur-containing tetraazafulvalenes the derivatives 1 - 3 were cross-coupled with different types of acetylenes via palladium-catalyzed reactions. Starting from the tetrabromoaryl derivative 3a, four bromine atoms could be replaced by 2-ethynylthiophene. Under analogous conditions, the methylsulfanyl esters 7 -11 could be obtained by employing 4-ethynylbenzoic acid 4-(methylsulfanyl)butylester 6. Lipoic acid could be integrated into tetraazafulvalenes successfully in a two step reaction. First, the Sonogashira coupling method yielded the compound 12 possessing two (4-anilino)ethynyl residues which were then condensed with lipoic acid to give derivative 13.
Whereas the NMR data suggest the predominance of prototropic form A, UV/vis spectra of the deeply colored tetraazafulvalenes are in favor with structure B rather than with structure A. DFT calculations at the B3LYP/6-31G(d) level showed that tautomeric form B is about 60 kJ/mol more stable than A. In addition, time-dependent density functional theory calculations support the substructure of two crossed diazaheptamethinemerocyanines.
Ternary Indides REMgIn (RE = Y, La–Nd, Sm, Gd–Tm, Lu). Synthesis, Structure and Magnetic Properties
Authors: Kraft Rainer , Valldor Martin , Kurowski Daniel , Hoffmann Rolf-Dieter , Pöttgen Rainer 
Published: August 2018

Abstract
The equiatomic rare earth-magnesium-indium compounds REMgIn (RE = Y, La-Nd, Sm, Gd- Tm, Lu) were prepared from the elements in sealed tantalum tubes inside a water-cooled sample chamber of an induction furnace. All compounds were characterized through their X-ray powder patterns. They crystallize with the hexagonal ZrNiAl type structure, space group P6̄̄2m, with three formula units per cell. The structure of SmMgIn was refined from X-ray single crystal diffractometer data: a = 761.3(2), c = 470.3(1) pm, wR2 = 0.0429, 380 F2 values and 14 variable parameters. The DyMgIn, HoMgIn, and TmMgIn structures have been analyzed using the Rietveld technique. The REMgIn structures contain two cystallographically independent indium sites, both with tri-capped trigonal prismatic coordination: In1Sm6Mg3 and In2Mg6Sm3. Together the magnesium and indium atoms form a three-dimensional [MgIn] network with Mg-Mg distances of 320 and Mg-In distances in the range 294 - 299 pm. Temperature dependent magnetic susceptibility data show Curie-Weiss behavior for DyMgIn, HoMgIn, and TmMgIn with experimental magnetic moments of 11.0(1) μB/Dy atom, 10.9(1) μB/Ho atom, and 7.5(1) μB/Tm atom. The three compounds order antiferromagnetically at TN = 22(2) K (DyMgIn), 12(1) K (HoMgIn), and 3(1) K (TmMgIn).
Synthese und Struktur von Meldrums Olefin/Synthesis and Structure of Meldrum’s Olefin
Authors: Kuhn Norbert , Al-Sheikh Ahmed , Kolb Hans-Jürgen , Richter Markus 
Published: August 2018

Abstract
Diisopropylidene ethylenetetracarboxylate, Meldrum’s olefin (4, Mel2) has been prepared from [HNEt3][(Mel)2CSMe] (8) and Meldrum’s acid (1, MelH2) in moderate yield. The X-ray analysis of 4 reveals a centrosymmetrical structure in which the two six-membered rings are folded along their carboxylate carbon axes by 34.9°) and linked by a conventional C-C double bond [1.3501(19) Å ]. The “unsymmetrical” structure of 8 is also discussed.
The Hexagonal Laves Phase MgIr2
Authors: Hlukhyy Viktor , Pöttgen Rainer 
Published: August 2018

Abstract
The hexagonal Laves phase MgIr2 was synthesized from the elements in a sealed tantalum tube in an induction furnace. MgIr2 was investigated by powder and single crystal X-ray data: P63/mmc, a = 516.9(1), c = 838.5(2) pm, wR2 = 0.0771, 135 F2 values, and 11 variable parameters. The magnesium atoms have coordination number (CN) 16 (12 Ir + 4 Mg), while the smaller iridium atoms, Ir1 and Ir2, both have CN 12 (6 Ir + 6 Mg). The Ir-Ir distances within the three-dimensional network of face- and corner-sharing Ir4/2 tetrahedra range from 250 to 267 pm. The magnesium atoms have one shorter (306 pm) and three longer (319 pm) magnesium contacts. The crystal chemistry of MgIr2 is briefly discussed and compared with the other binary Mg-Ir intermetallics.
Solvothermal Syntheses, Crystal Structures of Two New Thioantimonates(III) of the Mn2(L)Sb2S5 Family with L = Diethylenetriamine and N-Methyl-1,3-Diaminopropane and a Study of the Magnetic Properties of Four Compounds of the Series
Authors: Engelke L. , Stähler R. , Schur M. , Näther C. , Bensch W. , Pöttgen R. , Möller M. H. 
Published: August 2018

Abstract
The two new compounds Mn2(L)Sb2S5 (L = diethylenetriamine = DIEN, N-methyl-1,3- diaminopropane = MDAP) were prepared under solvothermal conditions using the elements as starting materials. Both compounds crystallise in the monoclinic space group P21/c with the lattice parameters a=10.669(7), b=12.805(2), c=12.072(1)Å , β =115.786(7)°,V =1485.1(4) Å3 for L = DIEN and a = 10.1859(7), b = 12.7806(6), c = 12.1256(8)Å , β = 110.173(8)°, V = 1481.7(2) Å3 for L = MDAP and Z = 4. The primary building units are SbS3 pyramids, MnS6 and MnS4N2 distorted octahedra. These primary building blocks are interconnected to form Mn2Sb2S4 hetero-cubane units. The hetero-cubanes share common corners, edges and faces thus forming a second heterocubane. These secondary building units are joined to form layers within the (100) plane. The connection mode yields ellipsoidal pores within the layers. The amines are exclusively bound to one of the two crystallographically independent Mn2+ cations and they point into the pores and between the layers separating the layers from each other. The interlayer separation and the size of the pores depend on the sterical requirements of the amine incorporated into the network. A pronounced distortion of the MnS4N2 octahedron results from a significant elongation of one Mn-S distance from 2.866 Å (L = methylamine, MA) to 3.185 Å for L = MDAP. The magnetic susceptibility curves are typical for low-dimensional antiferromagnetic materials and the large negative values for the Weiss constant Θ indicate strong antiferromagnetic exchange interactions. The magnetic properties are significantly influenced by the change of the Mn-S bonds introduced by the different amines. The compounds decompose at elevated temperatures with a two step reaction for L = MA and ethylenediamine and in a one step reaction for the bidentate acting amine molecules.
Thiakronenether-Metallkomplexe: Komplexe von Silber(I) und Quecksilber(II) mit Tetrathia-12-krone-4, Silber(I) und Cadmium(II) mit Hexathia-18-krone-6 und Silber(I) mit 3,6,9,14-Tetrathiabicyclo[9.2.1]tetradeca-11-13-dien / Thia Crown Ether Metal Complexes: Complexes of Silver(I) and Mercury(II) with Tetrathia-12-crown-4, Silver(I), and Cadmium(II) with Hexathia-18-crown-6, and Silver(I) with 3,6,9,14-Tetrathiabicyclo[9.2.1]tetradeca-11-13-diene
Authors: Pickardt Joachim , Chrzanowski Lars von , Steudel Ralf , Borowski Marina 
Published: August 2018

Abstract
Crystals of 1,4,7,10-tetrathiacyclododecane silver(I) trifluoromethanesulfonate, Ag(C8H16S4)- (CF3SO3), 1,4,7,10-tetrathiacyclododecane iodo mercury(II) hexaiododimercurate(II)methylene chloride [HgI(C8H16S4)][Hg2I6] · CH2Cl2, 1,4,7,10,13,16-hexathiacyclooctadecane silver(I) trifluoromethanesulfonate [Ag(C12H24S6)](CF3SO3), 1,4,7,10,13,16-hexathiacyclooctadecane diiodocadmium, [Cd(C12H24S6)I2], and bis-3,6,9,14-tetrathiabicyclo[9.2.1]tetradeca-11-13-diene silver(I) trifluoromethanesulfonate [Ag(C10H14S4)2](CF3SO3) were obtained by reaction of solutions of the ligands and the appropriate metal salts and their X-ray crystal structures determined.
Cazolobine, a New Sesquiterpene from Isolona hexaloba (Annonaceae)
Authors: Mathouet Hilarion , Cazoulat Isabelle , Oulyadi Hassan , Seguin Elisabeth , Daïch Adam , Elomri Abdelhakim 
Published: August 2018

Abstract
Methyl 7-(5’,5’-dimethyltetrahydrofuran-2’-yl)-3-methylocta-2,6-dieneoate (cazolobine), a new sesquiterpene derivative was isolated from the root of Isolona hexaloba (Annonaceae) collected in Gabon. The structure of cazolobine was elucidated on the basis of its spectral data, mainly MS and multiple-pulse NMR.
Pt-Dumbbells in Ba3Pt2: Interplay of Geometric and Relativistic Effects on Pt–Pt Bonding
Authors: Karpov Andrey , Wedig Ulrich , Jansen Martin 
Published: August 2018

Abstract
Ba3Pt2 has been synthesized by reaction of a 3 : 2 mixture of Ba and Pt at 1223 K in argon, and characterized by single-crystal X-ray structure determination and electrical resistivity measurements. Ba3Pt2 crystallizes in the Er3Ni2 structure type (space group R3̅ with a = 962.40(6), c = 1860.6(1) pm, Z = 9, R(F)N′ = 0.063, N′(hkl) = 777), and is isotypic to Ca3Pt2 and Sr3Pt2. The Pt atoms occur in pairs at a distance of 303 pm. According to the analysis of the Electron Localization Function and the Crystal Orbital Hamilton Population obtained from DFT band structure calculations, covalent bonding can be assumed in the Pt-dumbbells, although it is weaker in Ba3Pt2 than in Ca3Pt2. The peculiarities of the platinum compounds due to relativistic effects are elaborated by a comparison with theoretical results for Ca3Pd2. Ba3Pt2 exhibits metallic conductivity (ρ270 = 0.7 mΩ · cm), which is in accordance with band structure calculations.
Random Interstitial Halide Accommodation in an α,ω-Alkylidene-diammonium Template
Authors: Schneider Daniel , Schier Annette 
Published: August 2018

Abstract
N,N,N′,N′-Tetramethylethylenediammonium diiodide [Me2HNCH2]2I2 (1) as well as a set of I/Br- (2) and Br/Cl-mixed-halide salts (4 and 5) have been prepared, and their structures determined by single crystal X-ray diffraction. The results show the [Me2HNCH2]2
2+ dication to be a highly flexible template for halide inclusion, thereby tolerating the assembly of anions of different size, with phase widths of 0 ≤ x ≤ 2 for a monoclinic form with [Me2HNCH2]2I2−xBrx and 0 ≤ x ≤ 1 for a triclinic form with [Me2HNCH2]2Br2−xClx. The isotypic mixed halide compounds [Me2HNCH2]2IBr (2) and [Me2HNCH2]2BrCl (4) exhibit a statistical distribution of the anions in a structure of space group P21/c which is also found for the pure diiodide [Me2HNCH2]2I2 (1). With an excess of chloride (x>1 for Br2−xClx) this structure is converted into that of the pure dichloride, [Me2HNCH2]2Cl2 (6), with space group P1̅. In all cases the halide anions are trapped in voids between the dications and fixed to the ammonium centers by strong N-H· · ·X and weak C-H· · ·X hydrogen bonding.
Synthesis and Reactivity of Novel Alkali Metal Stannides
Authors: Schollmeier Thorsten , Englich Ulrich , Fischer Roland , Prass Ingo , Ruhlandt Karin , Schürmann Markus , Uhlig Frank 
Published: August 2018

Abstract
Reactivity and side products of reactions of diorganodihydridostannanes (R2SnH2, R = Me, nBu, tBu)) with various alkali metal compounds have been discussed. Alternatively, the synthesis and characterization of a family of novel potassium stannides are described as well. The compounds of type (RR’2Si)R”2SnK (R, R’= Me, Ph; R”= , Me, tBu, Ph) 4 - 9 were synthesized by reaction of potassium hydride with bis(silyl)stannides ((RR’2Si)2SnR”2). All compounds were characterized by multinuclear NMR spectroscopy. In addition, the tri-tert-butyltin compound 3 (LiSntBu3) and the unsymmetrical silyl substituted stannane 10 were characterized by X-ray crystallography.
Polymorphism of Trimeric Perfluoro-ortho-phenylene Mercury, [Hg(o-C6F4)]3
Authors: Haneline Mason R. , Gabbaï François P. 
Published: August 2018

Abstract
Three new modifications of trimeric perfluoro-ortho-phenylene mercury (2) have been investigated by single crystal X-ray diffraction. In each of these modifications, the molecules of 2 form extended stacks. Within each stack, the successive molecules are parallel and separated by approximately 3.3 - 3.4 Å. The packing observed in the different structures is rationalized on the basis of secondary mercury-π interactions, mercuriophilic interactions and electrostatic interactions. Altogether, little preference is given for one particular type of interaction. The packing appears to be dominated by non-directional van der Waals interactions between molecules of 2 which are largely aromatic and whose overall polarizability is magnified by relativistic effects at the mercury(II) centers.
Strukur und Reaktivität von Al2Cp*+ in der Gasphase. Ein experimenteller Beitrag zur Problematik der Aluminium-Aluminium- Doppelbindung / Structure and Reactivity of Al2Cp*+ in the Gas Phase. Experiments on the Problematic Nature of the Aluminum-Aluminum-Multiple Bond
Authors: Koch K. , Schnöckel H. 
Published: August 2018

Abstract
The cation Al2Cp*+ descending from the tetrahedral Al4Cp*4 Cluster after using LDI as ionisation method in an FT-ICR mass spectrometer reacts with Cl2 in the gas phase. The investigation of this reaction together with quantum chemical calculations gives a new approach to the question of existence and stability of an aluminum-aluminum double bond.
Synthesis of Some New Linear and Chiral Macrocyclic Pyridine Carbazides as Analgesic and Anticonvulsant Agents
Authors: Amr Abdel-Galil E. 
Published: August 2018

A series of 2,6-disubstituted pyridine derivatives were prepared from 2,6-diacetylpyridine or 2,6- dicarbonyl pyridine dichloride as starting materials. Reaction of 2,6-diacetylpyridine 1 with hydroxylamine hydrochloride or different aromatic aldehydes afforded the corresponding 2,6-diacetylpyridine dioxime and 2,6-bis-[β -(2-thienyl)acryloyl]pyridine derivatives 2 and 3, respectively. Additionally, N2,N2‘-(pyridine-2,6-dicarbonyl)-L-amino acid hydrazides 5 were prepared starting from 2,6- dicarbonyl pyridine dichloride via the corresponding esters 4. Compound 3 was reacted with hydroxylamine hydrochloride to afford the 2,6-bis-[β -(2-thienyl)acryloyl-oxime]-pyridine derivative 6. Treatment of compounds 2 or 6 with phenyl isocyanate or phenyl isothiocyanate in refluxing dioxane gave the corresponding semicarbazide or thiosemicarbazide derivatives 7 and 8, respectively. Their treatment with toluene-3,5-diisocyanate afforded the macrocyclic semicarbzides 9 and 10, respectively. The chiral thiosemicarbazides 11a,b were however, prepared by treating compounds 5a,b with phenyl isothiocyanate followed by cyclization with sodium hydroxide (2N) yielding the triazoles 12a,b. Finally, the hydrazides 5a,b were treated with toluene-3,5-diisocyanate to afford the chiral macrocyclic tetrapeptide semicarbazides 13a,b in reasonable yields, while the expected cyclic dipeptide 14 was not formed. The structure assignments of the new compounds were based on chemical and spectroscopic evidence.
The pharmacological screening showed that many of these compounds have good analgesic and anticonvulsant activities comparable to Voltarine® and Carbamazapine® used as reference drugs.
Materials with ZrCuSiAs-type Structure
Authors: Pöttgen Rainer , Johrendt Dirk 
Published: August 2018

Abstract
The discovery of high-temperature superconductivity in the fluoride-doped arsenide oxides REFeAs(O1−xFx) (RE = early rare earth element) with transition temperatures as high as 55 K has led to a true renaissance in superconductivity research. These arsenide oxides constitute a rather small fraction of a much larger family of compounds with the tetragonal ZrCuSiAs-type structure (space group P4/nmm), among them pnictide oxides and fluorides, chalcogenide oxides and fluorides as well as silicide and germanide hydrides. Besides the spectacular superconductivity, these materials have further interesting properties with respect to magnetic ordering, transparent semiconducting behavior or optical properties. The crystal chemical and chemical bonding peculiarities as well as the broadly varying physical properties are reviewed herein.
Reactions of 5(4H)-Oxazolones with Wittig-Horner Reagents: Novel Synthesis of Dioxopyrrolidinephosphonates and Phosphonoalkanoates with Anticipated Schistosomicidal Activity
Authors: Boulosa Leila S. , Arsanious Mona H.N. , Ewies Ewies F. , Ramzy Fatem 
Published: August 2018

Abstract
4-Benzylidene-2-phenyl-5(4H)-oxazolones react with Wittig-Horner reagents in the presence of alcoholic sodium alkoxide to give novel dioxopyrrolidinephosphonates, diethyl [3-(benzoylamino)- 1-cyano-2-oxo-4-phenylbut-3-en-1-yl]phosphonate and phosphonoalkenoate derivatives. Both the phosphonate adducts and the ester products were also isolated from the reaction of oxazolones with triethyl phosphonoacetate using alcoholic sodium ethoxide and/or sodium hydride as a base. Possible reaction mechanisms are considered, and the structural assignments are based on analytical and spectroscopic results. The biological evaluation of the new compounds is reported.
Photophysics of Ochratoxin A in Aqueous Solution
Authors: Steinbrück Dörte , Rasch Claudia , Kumke Michael U. 
Published: August 2018

Abstract
The photophysics of Ochratoxin A (OTA) in aqueous solution strongly depends on the pH. Due to its molecular structure OTA is prone to an excited state proton transfer reaction, which rules the photophysical properties. Based on results of absorption and fluorescence measurements the rate constants of the proton transfer reactions (forward and back reaction) were determined and subsequently, the pK*
a value was calculated. Based on the results, optimized experimental conditions for the analysis can be determined e. solvent conditions (HPLC chromatography) or excitation and emission wavelength (fluorescence spectroscopy).
Syntheses, single-crystal structure determination, and Raman spectra of Rb[C(CN)3] and Cs[C(CN)3]
Authors: Reckeweg Olaf , Schulz Armin , DiSalvo Francis J. 
Published: August 2018

Abstract
Extracting residues of an aqueous solutions containing equimolar amounts of K[C(CN)3] and RbF or CsF, respectively, with absolute ethanol, yields triangular, transparent colorless crystals of Rb[C(CN)3] and Cs[C(CN)3] after the ethanol was allowed to evaporate. The compounds are isotypic and crystallize isopointal to calcite in space group R3̅c (no. 167) with the cell parameters a=809.9(1) and c=1461.3(3) pm and a=843.29(9) and c=1459.9(2) pm, respectively. Single crystals were used to record the Raman spectra of the title compounds.
Freie und Membrangebundene Ribosomen in der Rattenleber: Tagesrhytmik und hormonale Einflüsse / Free and Membrane-bound Ribosomes in Rat Liver: Daily Rhythm and Hormonal Influences
Authors: Dieminger Lothar 
Published: August 2018

Free and membrane-bound ribosomes were isolated from rat liver and quantitized by photometric methods. The amount of membrane-bound ribosomes remaines relatively constant over 24 hours whereas the amount of free ribosomes changes considerably: a maximum appears between 6-9 h, a minimum between 18-21 h. Fasting the animals increases the overall variance.
Injections of cortisol 4 hours before killing the animals increases the total amount of ribosomes and induces a definite maximum of membrane-bound ribosomes at 6 h. The maximum of free ribosomes appears at the same time as in control animals. In contrast to cortisol, corticosterone has no effect on the total amount of ribosomes, it induces, however, a maximum of membrane-binding between 18-21 h. Also in this case the maximum of free ribosomes remains unchanged.
In the evening, the protein content of free ribosomes decreases whereas a change was not observed in membrane-bound ribosomes. Cortisol increases the protein content in free and membrane- bound ribosomes.