bluuebunny/crossref_metadata_2025_split huggingface dataset:
Amazonian struggles for recognition
Authors: Fraser James Angus 
Published: June 2018

Since the 1988 Constitution, forest peoples of Brazilian Amazonia have been struggling for territorial recognition. Yet studies of recognition in post colonial contexts, based on cases with clear settler/indigenous distinctions, are highly critical of recognition, seeing it as a form of “neoliberal multiculturalism,” a co‐option of subaltern identities with limited emancipatory potential. I question these critiques by examining struggles for legal and intersubjective recognition of subaltern identity categories “Índio” and “Agroextractivista” and corresponding territories of the “Terra Indigena” and “Reserva Extractivista” on the Madeira and Tapajós Rivers in Brazilian Amazonia, where heterogeneous origins of forest peoples belie simple settler/indigenous distinctions. I engage a key question, the relationships of subaltern peoples with state institutions, and highlight a finding, the relevance of the state's “proximity,” often underestimated in the literature. I build a theory of decolonial recognition combining Axel Honneth's idea of recognition as love, rights and solidarity with David Scott's late‐Foucauldian reworking of Frantz Fanon. Herein, the Fanonian colonised subjectivity is shaped by the negation of love, rights and solidarity, that is to say, misrecognition. The subject requires legal and intersubjective recognition in order to positively incorporate love, rights and solidarity into their “practices of techniques of the self.” On the Tapajós, territorial struggles are more successful owing to a stronger sphere of legal recognition – the presence of state institutions – and a history of Church and union grassroots organisation, both supporting greater intersubjective recognition among forest peoples. On the Madeira, a much weaker sphere of legal recognition has resulted in a situation of intractable conflict around territorial struggles which have correspondingly less intersubjective recognition. I conclude that a theory of decolonial recognition is of considerable utility in elucidating the dynamics of subaltern emancipatory struggles for territory.
Reviewer Acknowledgements
Authors: Smith Robert 
Published: June 2018

Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 6, Number 7 Alperen Yandı, Abant İzzet Baysal University, TurkeyFatma Ozudogru, Usak University, TurkeyHatice Öztürk, Artvin Çoruh University, Turkeyİbrahim Yaşar Kazu, Firat University, TurkeyJohn Cowan, Edinburgh Napier University, UKJon S. Turner, Missouri State University, USALaima Kyburiene, Kaunas University of Applied Sciences, LithuaniaMan-fung Lo, The Hong Kong Polytechnic University, Hong KongMaria Pavlis Korres, Hellenic Open University, GreeceMaurizio Sajeva, Pellervo Economic Research PTT, FinlandMin Gui, Wuhan University, ChinaNuran Bayram, Uludag Universtiy, TurkeyOzgur Demirtas, Inonu University, TurkeyRichard H. Martin, Mercer University, USASayim Aktay, Mugla Sitki Kocman University, TurkeySenem Seda Şahenk Erkan, Marmara University, TurkeySeyfullah Tingir, Florida State University, USASirin Akbulut Demirci, Uludag University, TurkeyYalçın Dilekli, Aksaray University, Turkey Robert SmithEditorial AssistantOn behalf of,The Editorial Board of Journal of Education and Training StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://jets.redfame.com
Polarized Versus High-Intensity Multimodal Training in Recreational Runners
Authors: Carnes Andrew J. , Mahoney Sara E. 
Published: June 2018

Purpose: This study longitudinally compared changes in running performance (5-km time trial) and fitness (maximal oxygen uptake [VO2max] and body composition [BC]) between polarized training and CrossFit Endurance (CFE) in recreational runners. Methods: Participants (N = 21) completed 12 wk of CFE or polarized endurance training (POL). Both groups trained 5 d·wk−1. POL ran 5 d·wk−1, whereas CFE ran 3 d·wk−1 and performed CrossFit 3 d·wk−1 (run + CrossFit 1 d·wk−1). Intensity was classified as low, moderate, or high (zone 1, 2, or 3) according to ventilatory thresholds. POL was prescribed greater volume (295 [67] min·wk−1), distributed as 85%/5%/10% in Z1/Z2/Z3. CFE emphasized a lower volume (110 [18] min·wk−1) distribution of 48%/8%/44%. Results: POL ran 283 (75.9) min·wk−1 and 47.3 (11.6) km·wk−1, both exceeding the 117 (32.2) min·wk−1 and 19.3 (7.17) km·wk−1 in CFE (P < .001). The POL distribution (74%/11%/15%) had greater total and percentage Z1 (P < .001) than CFE (46%/15%/39%), which featured higher percentage Z3 (P < .001). Time trial improved −93.8 (40.4) s (−6.21% [2.16%]) in POL (P < .001) and −84.2 (65.7) s (−5.49% [3.56%]) in CFE (P = .001). BC improved by −2.45% (2.59%) fat in POL (P = .02) and −2.62% (2.53%) in CFE (P = .04). The magnitude of improvement was not different between groups for time trial (P = .79) or BC (P = .88). Both groups increased VO2max (P ≤ .01), but with larger magnitude (P = .04, d = 0.85) in POL (4.3 [3.6] mL·kg·min−1) than CFE (1.78 [1.9] mL·kg·min−1). Conclusions: Recreational runners achieved similar improvement in 5-km performance and BC through polarized training or CFE, but POL yielded a greater increase in VO2max. Extrapolation to longer distances requires additional research.
Influence of Foam Rolling Velocity on Knee Range of Motion and Tissue Stiffness: A Randomized, Controlled Crossover Trial
Authors: Wilke Jan , Niemeyer Philipp , Niederer Daniel , Schleip Robert , Banzer Winfried 
Published: June 2018

Context: Foam rolling (FR) increases joint range of motion (RoM), but the optimal training parameters are unknown. Objective: To investigate the effect of FR velocity on RoM and tissue stiffness. Design: Randomized, controlled crossover trial. Setting: University. Participants: A total of 17 healthy, physically active adults (10 females; 25 [2] y). Interventions: (1) Four 45-second high-velocity FR of the anterior thigh (FAST-FR), (2) four 45-second slow-velocity FR of the anterior thigh (SLOW-FR), and (3) inactive control. Outcome Measures: Maximal knee-flexion RoM (ultrasonic movement analysis) and anterior thigh tissue stiffness (semielectronic tissue compliance meter) assessed pre, immediately post (T0), as well as 5 (T5) and 10 (T10) minutes postintervention. Statistical analysis included Friedman tests with adjusted post hoc comparisons (Wilcoxon tests). Results: According to omnibus testing, RoM remained unchanged in all 3 conditions and at all time points (P > .05), while differences were found for tissue stiffness (P < .05). Post hoc tests revealed significant decreases following FAST-FR (T5: −17%, T10: −24%; P < .05) and SLOW-FR (T10: −15%; P < .05). The observed stiffness changes were significant in comparison with control (P < .01), but no difference was found between the 2 FR conditions (P > .05). Conclusions: FR of the anterior thigh decreases myofascial stiffness regardless of velocity. The lack of effects on RoM contrasts findings of recent literature and warrants further investigation.
Squamous cell carcinoma in the anophthalmic socket: a series of four cases with HPV-16 profiling
Authors: McGrath Lindsay A , Salvi Sachin Madhusudan , Sandramouli Soupramanien , Bhatt Rina , Cuschieri Kate , Mudhar Hardeep Singh 
Published: June 2018

PurposeTo present the clinical and histological features of squamous cell carcinoma (SCC) in the anophthalmic socket in four adult patients, and to determine the presence of human papillomavirus infection (HPV).MethodsRetrospective case series of four adult patients with SCC of the anophthalmic socket. P16 immunohistochemistry and HPV testing was carried out in all cases. The authors report clinical findings, histopathology, management and outcomes for all four patients with conjunctival SCC. Previously reported cases of conjunctival SCC in anophthalmic sockets were reviewed.ResultsFour adult patients presented with eyelid lumps, discharge or change in prosthesis fit. Common examination findings included papillomatous changes, eyelid masses and epithelial changes. Three out of the four cases (75%) were positive for p16 by immunohistochemistry and the same cases positive for HPV-16 DNA. All patients received cryotherapy, topical or intralesional chemotherapy. Two patients proceeded to exenteration for control of invasive disease.ConclusionsTo the authors’ knowledge, this is the largest series of SCC in the anophthalmic socket with comprehensive annotation of HPV status. Although socket conjunctiva is protected from environmental radiation, there is still a risk of neoplastic transformation in this tissue, thus patient education and regular checking of sockets by ophthalmologists should be undertaken as a preventative measure. The potential role of HPV in these tumours warrants further investigation.
Speaking up about patient safety concerns: the influence of safety management approaches and climate on nurses’ willingness to speak up
Authors: Alingh Carien W , van Wijngaarden Jeroen D H , van de Voorde Karina , Paauwe Jaap , Huijsman Robbert 
Published: June 2018

BackgroundSpeaking up is important for patient safety, but healthcare professionals often hesitate to voice their concerns. Direct supervisors have an important role in influencing speaking up. However, good insight into the relationship between managers’ behaviour and employees’ perceptions about whether speaking up is safe and worthwhile is still lacking.AimTo explore the relationships between control-based and commitment-based safety management, climate for safety, psychological safety and nurses’ willingness to speak up.MethodsWe conducted a cross-sectional survey study, resulting in a sample of 980 nurses and 93 nurse managers working in Dutch clinical hospital wards. To test our hypotheses, hierarchical regression analyses (at ward level) and multilevel regression analyses were conducted.ResultsSignificantly positive associations were found between nurses’ perceptions of control-based safety management and climate for safety (β=0.74; p<0.001), and between the perceived levels of commitment-based management and team psychological safety (β=0.36; p<0.01). Furthermore, team psychological safety is found to be positively related to nurses’ speaking up attitudes (B=0.24; t=2.04; p<0.05). The relationship between nurse-rated commitment-based safety management and nurses’ willingness to speak up is fully mediated by team psychological safety.ConclusionResults provide initial support that nurses who perceive higher levels of commitment-based safety management feel safer to take interpersonal risks and are more willing to speak up about patient safety concerns. Furthermore, nurses’ perceptions of control-based safety management are found to be positively related to a climate for safety, although no association was found with speaking up. Both control-based and commitment-based management approaches seem to be relevant for managing patient safety, but when it comes to encouraging speaking up, a commitment-based safety management approach seems to be most valuable.
How important is social support in determining patients’ suitability for transplantation? Results from a National Survey of Transplant Clinicians
Authors: Ladin Keren , Emerson Joanna , Butt Zeeshan , Gordon Elisa J , Hanto Douglas W , Perloff Jennifer , Daniels Norman , Lavelle Tara A 
Published: June 2018

BackgroundNational guidelines require programmes use subjective assessments of social support when determining transplant suitability, despite limited evidence linking it to outcomes. We examined how transplant providers weigh the importance of social support for kidney transplantation compared with other factors, and variation by clinical role and personal beliefs.MethodsThe National survey of the American Society of Transplant Surgeons and the Society of Transplant Social Work in 2016. Using a discrete choice approach, respondents compared two hypothetical patient profiles and selected one for transplantation. Conditional logistic regression estimated the relative importance of each factor; results were stratified by clinical role (psychosocial vs medical/surgical providers) and beliefs (outcomes vs equity).ResultsFive hundred and eighy-four transplant providers completed the survey. Social support was the second most influential factor among transplant providers. Providers were most likely to choose a candidate who had social support (OR=1.68, 95% CI 1.50 to 1.86), always adhered to a medical regimen (OR=1.64, 95% CI 1.46 to 1.88), and had a 15 years life expectancy with transplant (OR=1.61, 95% CI 1.42 to 1.85). Psychosocial providers were more influenced by adherence and quality of life compared with medical/surgical providers, who were more influenced by candidates' life expectancy with transplant (p<0.05). For providers concerned with avoiding organ waste, social support was the most influential factor, while it was the least influential for clinicians concerned with fairness (p<0.05).ConclusionsSocial support is highly influential in listing decisions and may exacerbate transplant disparities. Providers’ beliefs and reliance on social support in determining suitability vary considerably, raising concerns about transparency and justice.
Identification of novel mRNAs and lncRNAs associated with mouse experimental colitis and human inflammatory bowel disease
Authors: Rankin Carl Robert , Theodorou Evangelos , Man Law Ivy Ka , Rowe Lorraine , Kokkotou Efi , Pekow Joel , Wang Jiafang , Martín Martín G. , Pothoulakis Charalabos , Padua David 
Published: June 2018

Inflammatory bowel disease (IBD) is a complex disorder that is associated with significant morbidity. While many recent advances have been made with new diagnostic and therapeutic tools, a deeper understanding of its basic pathophysiology is needed to continue this trend toward improving treatments. By utilizing an unbiased, high-throughput transcriptomic analysis of two well-established mouse models of colitis, we set out to uncover novel coding and noncoding RNAs that are differentially expressed in the setting of colonic inflammation. RNA-seq analysis was performed using colonic tissue from two mouse models of colitis, a dextran sodium sulfate-induced model and a genetic-induced model in mice lacking IL-10. We identified 81 coding RNAs that were commonly altered in both experimental models. Of these coding RNAs, 12 of the human orthologs were differentially expressed in a transcriptomic analysis of IBD patients. Interestingly, 5 of the 12 of human differentially expressed genes have not been previously identified as IBD-associated genes, including ubiquitin D. Our analysis also identified 15 noncoding RNAs that were differentially expressed in either mouse model. Surprisingly, only three noncoding RNAs were commonly dysregulated in both of these models. The discovery of these new coding and noncoding RNAs expands our transcriptional knowledge of mouse models of IBD and offers additional targets to deepen our understanding of the pathophysiology of IBD. NEW & NOTEWORTHY Much of the genome is transcribed as non-protein-coding RNAs; however, their role in inflammatory bowel disease is largely unknown. This study represents the first of its kind to analyze the expression of long noncoding RNAs in two mouse models of inflammatory bowel disease and correlate them to human clinical samples. Using high-throughput RNA-seq analysis, we identified new coding and noncoding RNAs that were differentially expressed such as ubiquitin D and 5730437C11Rik.
Molecular Profiling of Patients with Pancreatic Cancer: Initial Results from the Know Your Tumor Initiative
Authors: Pishvaian Michael J. , Bender Robert J. , Halverson David , Rahib Lola , Hendifar Andrew E. , Mikhail Sameh , Chung Vincent , Picozzi Vincent J. , Sohal Davendra , Blais Edik M. , Mason Kimberly , Lyons Emily E. , Matrisian Lynn M. , Brody Jonathan R. , Madhavan Subha , Petricoin Emanuel F. 
Published: June 2018

Abstract
Purpose: To broaden access to and implementation of precision medicine in the care of patients with pancreatic cancer, the Know Your Tumor (KYT) program was initiated using a turn-key precision medicine system. Patients undergo commercially available multiomic profiling to determine molecularly rationalized clinical trials and off-label therapies.
Experimental Design: Tumor samples were obtained for 640 patients from 287 academic and community practices covering 44 states. College of American Pathologists/Clinical Laboratory Improvement Amendments–accredited laboratories were used for genomic, proteomic, and phosphoprotein-based molecular profiling.
Results: Tumor samples were adequate for next-generation sequencing in 96% and IHC in 91% of patients. A tumor board reviewed the results for every patient and found actionable genomic alterations in 50% of patients (with 27% highly actionable) and actionable proteomic alterations (excluding chemopredictive markers) in 5%. Actionable alterations commonly found were in DNA repair genes (BRCA1/2 or ATM mutations, 8.4%) and cell-cycle genes (CCND1/2/3 or CDK4/6 alterations, 8.1%). A subset of samples was assessed for actionable phosphoprotein markers. Among patients with highly actionable biomarkers, those who received matched therapy (n = 17) had a significantly longer median progression-free survival (PFS) than those who received unmatched therapy [n = 18; PFS = 4.1 vs. 1.9 months; HR, 0.47; 95% confidence interval (CI): 0.24–0.94; Padj = 0.03].
Conclusions: A comprehensive precision medicine system can be implemented in community and academic settings, with highly actionable findings observed in over 25% of pancreatic cancers. Patients whose tumors have highly actionable alterations and receive matched therapy demonstrated significantly increased PFS. Our findings support further prospective evaluation of precision oncology in pancreatic cancer. Clin Cancer Res; 24(20); 5018–27. ©2018 AACR.
Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption
Authors: Martin Océane C.B. , Naud Nathalie , Taché Sylviane , Debrauwer Laurent , Chevolleau Sylvie , Dupuy Jacques , Chantelauze Céline , Durand Denis , Pujos-Guillot Estelle , Blas-Y-Estrada Florence , Urbano Christine , Kuhnle Gunter G.C. , Santé-Lhoutellier Véronique , Sayd Thierry , Viala Didier , Blot Adeline , Meunier Nathalie , Schlich Pascal , Attaix Didier , Guéraud Françoise , Scislowski Valérie , Corpet Denis E. , Pierre Fabrice H.F. 
Published: June 2018

Abstract
Red meat is probably carcinogenic to humans (WHO/IARC class 2A), in part through heme iron-induced lipoperoxidation. Here, we investigated whether red meat promotes carcinogenesis in rodents and modulates associated biomarkers in volunteers, speculating that an antioxidant marinade could suppress these effects via limitation of the heme induced lipid peroxidation. We gave marinated or non-marinated beef with various degrees of cooking to azoxymethane-initiated rats, Min mice, and human volunteers (crossover study). Mucin-depleted foci were scored in rats, adenoma in Min mice. Biomarkers of lipoperoxidation were measured in the feces and urine of rats, mice, and volunteers. The organoleptic properties of marinated meat were tested. Fresh beef increased colon carcinogenesis and lipoperoxidation in rats and mice and lipoperoxidation in humans. Without an adverse organoleptic effect on meat, marinade normalized peroxidation biomarkers in rat and mouse feces, reduced peroxidation in human feces and reduced the number of Mucin-depleted foci in rats and adenoma in female Min mice. This could lead to protective strategies to decrease the colorectal cancer burden associated with red meat consumption. Cancer Prev Res; 11(9); 569–80. ©2018 AACR.
Thoracic Aorta Calcification and Noncardiovascular Disease–Related Mortality
Authors: Thomas Isac C. , Thompson Caroline A. , Yang Mingan , Allison Matthew A. , Forbang Nketi I. , Michos Erin D. , McClelland Robyn L. , Budoff Matthew J. , Criqui Michael H. 
Published: June 2018

Objective—
Arterial calcification is highly correlated with underlying atherosclerosis. Arterial calcification of the thoracic aorta is evident in many older individuals at high susceptibility to aging-related diseases and non-cardiovascular disease (CVD)–related mortality. In this study, we evaluated the association of thoracic aorta calcification (TAC) with non-CVD morbidity and mortality.

Approach and Results—
We analyzed data from participants in the Multi-Ethnic Study of Atherosclerosis, a prospective cohort study of subclinical atherosclerosis, in which participants underwent cardiac computed tomography at baseline and were followed longitudinally for incident CVD events and non-CVD events. Using modified proportional hazards models accounting for the competing risk of CVD death and controlling for demographics, CVD risk factors, coronary artery calcium, and CVD events, we evaluated whether TAC was independently associated with non-CVD morbidity and mortality. Among 6765 participants (mean age, 62 years), 704 non-CVD deaths occurred for a median follow-up of 12.2 years. Compared with no TAC, the highest tertile of TAC volume was associated with a higher risk of non-CVD mortality (hazard ratio, 1.56; 95% confidence interval, 1.23–1.97), as well as several non-CVD diagnoses, including hip fracture (2.14; 1.03–4.46), chronic obstructive pulmonary disease (2.06; 1.29–3.29), and pneumonia (1.79; 1.30–2.45), with magnitudes of association that were larger than for those of coronary artery calcium.

Conclusions—
TAC is associated with non-CVD morbidity and non-CVD mortality, potentially through a pathway that is unrelated to atherosclerosis. TAC may be a general marker of biological aging and an indicator of increased risk of non-CVD and death.
Frequency of Cardiac Rhythm Abnormalities in a Half Million Adults
Authors: Khurshid Shaan , Choi Seung Hoan , Weng Lu-Chen , Wang Elizabeth Y. , Trinquart Ludovic , Benjamin Emelia J. , Ellinor Patrick T. , Lubitz Steven A. 
Published: June 2018

Background:
The frequency of cardiac rhythm abnormalities and their risk factors in community-dwelling adults are not well characterized.

Methods:
We determined the frequency of rhythm abnormalities in the UK Biobank, a national prospective cohort. We tested associations between risk factors and incident rhythm abnormalities using multivariable proportional hazards regression.

Results:

Of 502 627 adults (median age, 58 years [interquartile range, 13]; 54.4% women), 2.35% had a baseline rhythm abnormality. The prevalence increased with age with 4.84% of individuals aged 65 to 73 years affected. During 3 368 332 person-years of follow-up, 15 906 new rhythm abnormalities were detected (4.72 per 1000 person-years; 95% confidence interval [CI]: 4.65–4.80). Atrial fibrillation (3.11 per 1000 person-years; 95% CI: 3.05–3.17), bradyarrhythmias (0.89 per 1000 person-years; 95% CI: 0.86–0.92), and conduction system diseases (1.06 per 1000 person-years; 95% CI: 1.02–1.09) were more common than supraventricular (0.51 per 1000 person-years; 95% CI: 0.48–0.53) and ventricular arrhythmias (0.57 per 1000 person-years; 95% CI: 0.55–0.60). Older age (hazard ratio [HR]: 2.35 per 10-year increase; 95% CI: 2.29–2.41;
P
<0.01), male sex (HR: 1.83; 95% CI: 1.76–1.89;
P
<0.01), hypertension (HR: 1.49; 95% CI: 1.44–1.54;
P
<0.01), chronic kidney disease (HR: 1.95; 95% CI: 1.67–2.27;
P
<0.01), and heart failure (HR: 1.99; 95% CI: 1.76–2.26;
P
<0.01) were associated with new rhythm abnormalities.

Conclusions:
The frequency of rhythm abnormalities in middle-aged to older community-dwelling adults is substantial. Atrial fibrillation, bradyarrhythmias, and conduction system diseases account for most rhythm conditions.