bluuebunny/crossref_metadata_2025_split huggingface dataset:
Como ter sucesso nas artes sem ser um homem?
Authors: Sofio Séverine 
Published: December 2018

Neste artigo propõe-se um conjunto de conselhos para art istas mulheres do passado para que sejam reconhecidas em vida e organizem a preservação póstuma de seus nomes e suas obras, com vistas a inscrevê-los na história. Inspiramo-nos em pesquisas sobre a população de pintoras, escultoras e gravadoras ativas na França na primeira metade do século XIX e em trabalhos sociológicos e históricos acerca da construção da reputação artística e da inscrição dos nomes na memória coletiva. Assim, de um modo não desprovido de distanciamento irônico, sugerese às artistas mulheres: partir com boas cartas na mão; fazer boas escolhas; não perder tempo em se fazer (re)conhecer; saber se vender; e pensar na posteridade.
Otras protagonistas del arte argentino
Authors: Gluzman Georgina 
Published: December 2018

A partir de 1911, os Salões Nacionais da Argentina ofereceram às mulheres artistas a opor tunidade de tornar seu trabalho notório e ganhar reconhecimento. Este artigo analisa suas participações desde 1924, ano da consagração de Raquel Forner, até 1939, quando Ana Weiss de Rossi obteve o prêmio máximo. Além disso, são analisadas as trajetórias de três artistas (Catalina Mórtola de Bianchi, María Carmen Portela Cantilo e Hildara Pérez de Llansó) que encontraram no Salão Nacional um caminho (embora não fosse o único) para serem apresentadas ao público e à crítica. A recepção, a fortuna crítica e a inserção nos museus dessas cinco mulheres artistas, quatro das quais foram eliminadas da história da arte, são examinadas.
Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in
Ldl
Receptor-Null Mice
Authors: Babaev Vladimir R. , Ding Lei , Zhang Youmin , May James M. , Ramsey Stephen A. , Vickers Kasey C. , Linton MacRae F. 
Published: December 2018

Objective—
Macrophages express 3 Akt (protein kinase B) isoforms, Akt1, Akt2, and Akt3, which display isoform-specific functions but may be redundant in terms of Akt survival signaling. We hypothesize that loss of 2 Akt isoforms in macrophages will suppress their ability to survive and modulate the development of atherosclerosis.

Approach and Results—

To test this hypothesis, we reconstituted male
Ldlr
−/−
mice with double
Akt2/Akt3
knockout hematopoietic cells expressing only the Akt1 isoform (Akt1
only
). There were no differences in body weight and plasma lipid levels between the groups after 8 weeks of the Western diet; however, Akt1
only
→
Ldlr
−/−
mice developed smaller (57.6% reduction) atherosclerotic lesions with more apoptotic macrophages than control mice transplanted with WT (wild type) cells. Next, male and female
Ldlr
−/−
mice were reconstituted with double
Akt1/Akt2
knockout hematopoietic cells expressing the Akt3 isoform (Akt3
only
). Female and male Akt3
only
→
Ldlr
−/−
recipients had significantly smaller (61% and 41%, respectively) lesions than the control WT→
Ldlr
−/−
mice. Loss of 2 Akt isoforms in hematopoietic cells resulted in markedly diminished levels of white blood cells, B cells, and monocytes and compromised viability of monocytes and peritoneal macrophages compared with WT cells. In response to lipopolysaccharides, macrophages with a single Akt isoform expressed low levels of inflammatory cytokines; however, Akt1
only
macrophages were distinct in expressing high levels of antiapoptotic
Il10
compared with WT and Akt3
only
cells.

Conclusions—

Loss of 2 Akt isoforms in hematopoietic cells, preserving only a single Akt1 or Akt3 isoform, markedly compromises monocyte and macrophage viability and diminishes early atherosclerosis in
Ldlr
−/−
mice.
Two new species of Cypretta Vávra, 1895 (Crustacea, Ostracoda) from Thailand and discussion of genus
Authors: SAVATENALINTON SUKONTHIP 
Published: December 2018

Two Cypretta species from Thailand are described: Cypretta aculeata n. sp. and Cypretta triangulata n. sp. Cypretta aculeata n. sp. can be characterized chiefly by the valve surface equipped with long setae, spine-like bristle and distinctive pits, the presence of tubercles on postero-ventral margin of the internal left valve and the denticulated ridge on the postero-ventral part of the internal right valve, the long d1 seta on the second thoracopod (T2), and the long Sp seta on the caudal ramus (CR). Based on the valve surface ornamentation, C. aculeata n. sp. is similar to C. globosa (Brady, 1886), C. intonsa Furtos, 1936, C. spinosa Cohuo-Durán et al., 2013 and C. vivacis Würdig & Pinto 1993. A key to the species within this group is thus provided. The main diagnostic features of Cypretta triangulata n. sp. are the triangular carapace in the dorsal view, the absence of tubercles on the postero-ventral margin of the internal left valve, the presence of denticulated ridge on the postero-ventral part of the internal right valve, the short d1 seta on T2 and the long Sp seta on the CR. The diagnostic characters for the species identification of the genus Cypretta are briefly discussed with regard to the morphology and number of the septa and lunules, the traits of the internal side of the valves, the features of soft body parts (such as the mandible, the thoracopods and the CR) and the morphological aspects of the hemipenis.
Full Cycle for Self-Service?
Authors: Regan William J. 
Published: December 2018

In the post-World War II period the use of self-service has spread horizontally to practically all types of retail stores on the minimum-service level. Whether labeled “self-selection,” “display merchandising,” “selective open selling,” “simplified selling,” or something similar, all of these represent variously lesser degrees of the supermarket concept of self-service. Whatever it is called, it refers to a still rapidly developing technology co-ordinating the merchandise-presentation efforts of retail stores. This article summarizes the pressures that have been exerted upon retail stores to adopt self-service in greater measure and then identifies the main reasons why some stores prefer to extend more personalized service.
Competitive Pricing in Railroad Freight Rates
Authors: Dean Joel 
Published: December 2018

The economic history of the railroads and the problems faced by them are in many ways unique. However, many of the railroads’ problems are the outgrowth of failure to apply pricing principles which have a universal applicability. Faulty pricing practices, including inadequate attention to customer alternatives, pricing improperly related to the railroad's own costs, and failure to use price as a sales incentive to reduce costs explain many of the railroads’ present difficulties. Dr. Dean shows how adoption of sound pricing principles could bring about competitive changes with far-reaching effects.
Progress in Deriving “Marketing Laws”
Authors: Butler B. F. 
Published: December 2018

A start is being made in applying principles of advanced mathematics to problems of business competition. The author describes what he calls “business theorems,” derived in the same manner as the laws governing physical sciences. He believes that theorems will help management to go more directly to the heart of the problem … by indicating the feasibility of objectives and by isolating the really important considerations from irrelevant factors.
Significant differences in patients with a complete insufficiency of the great versus small saphenous vein
Authors: Pochec Katarzyna , Mühlberger Dominic , Hummel Thomas , Stücker Markus , Reich-Schupke Stefanie 
Published: December 2018

Objectives Most studies on diagnostics and therapy of saphenous veins focus on great saphenous vein or sum up great and small saphenous vein. This study compares patients with an insufficiency of the great saphenous vein versus small saphenous vein. Methods Prospective study including 50 patients with untreated insufficiency of the great saphenous vein or small saphenous vein, respectively. Patients got a standardised phlebological examination and filled a vein-specific life quality questionnaire (SQOR-V). Results Great saphenous vein patients were significantly younger (p = 0.001), had more visible varicose veins (p < 0.001), a higher Venous Clinical Severity Score (p = 0.002) and had more symptoms, especially at midday (p = 0.0030) and evening (p = 0.078). They had significantly more concerns about worsening of their varicose veins (p = 0.009) and a vein disease in family members (p = 0.005). Conclusion Great saphenous vein patients have more and sooner symptoms than small saphenous vein patients. This study discusses if the difference in symptoms is related to the difference in tributaries and a therapy of the tributaries is able to reduce the symptoms.
Extended Breastfeeding in Poland: Knowledge of Health Care Providers and Attitudes on Breastfeeding Beyond Infancy
Authors: Baranowska Barbara , Malinowska Marta , Stanaszek Ewelina , Sys Dorota , Bączek Grażyna , Doroszewska Antonina , Tataj-Puzyna Urszula , Rabijewski Michał 
Published: December 2018

Background: Extended breastfeeding is rare in Poland, and lack of acceptance and understanding is often evident in public opinion. The ability to provide reliable information about breastfeeding beyond infancy depends on health professionals’ levels of knowledge and attitudes. They are considered by most parents in Poland to be authorities in the field of child nutrition. Research aims: To determine (1) the level of knowledge and the attitudes of Polish health professionals towards extended breastfeeding; (2) the relationship between personal breastfeeding experience and attitudes towards extended breastfeeding; and (3) the relationship between knowledge about breastfeeding beyond twelve months and attitudes towards breastfeeding beyond infancy. Methods: A one-group prospective, cross-sectional, self-report style survey was used. The convenience sample ( N = 495) comprised gynaecologists, neonatologists and midwives. Data were collected via an online questionnaire and the results were analyzed with the use of descriptive statistics, a chi-square independence test, Fisher’s exact test, post-hoc testing, and two-part tables using SPSS. Results: Most of the respondents (76.7%; n = 384) had a low level of knowledge about the benefits of breastfeeding beyond twelve months and even emphasized that this nutritional choice could have negative impacts. There was a positive correlation ( F = 105.847; p = < .01) between levels of knowledge and respondents’ attitudes towards breastfeeding beyond infancy. Attitudes were also influenced by the length of time respondents had breastfed. Conclusion: Healthcare providers have an insufficient level of knowledge about extended breastfeeding and need further education in this area.
Assessment of Technology Use and Technology Preferences for HIV Prevention Among Hispanic Women
Authors: Villegas Natalia , Cianelli Rosina , de Tantillo Lila , Warheit Melanie , Montano Nilda Peragallo , Ferrer Lilian , Patel Shefali 
Published: December 2018

Introduction: HIV transmission presents an ongoing risk to Hispanic women, and prevention efforts remain a priority. The use of technology to prevent HIV transmission among Hispanic women and those of lower socioeconomic status underscore the need for effective implementation of technology. The purpose of this study is to describe technology preferences and predictors of the use of the internet for HIV prevention among low-income Hispanic women. Method: A secondary analysis was conducted using baseline data from an intervention to prevent HIV among 320 Hispanic women. The parent study was SEPA, Salud (health), Educación (education), Promoción (promotion), y [and] Autocuidado (self-care). Results: Most participants reported using personal technology, such as smartphones (90.6%), the internet (78.1%), and personal email (67.5%), every day. Most (71.3%) participants were open to learning about HIV education via the internet. In the logistic regression analysis, education and time since the last visit to the health care provider were significant predictors of the use of the internet to learn about HIV prevention, after controlling for age, living with the partner, and years living in the United States. Conclusion: Hispanic women demonstrated high levels of comfort with different forms of technology. These results indicated the potential to expand future HIV intervention efforts by implementing electronic dissemination of bilingual and culturally appropriate information for Hispanic women of diverse ages.
Increasing Awareness of the All of Us Research Program in Latino Communities
Authors: Cuellar Norma G. , Aquino Elizabeth , Barreto Sara Cruet , Grau Grace , Gularte-Rinaldo Jeneva , Martinez Gail , Vital Veronica 
Published: December 2018

Introduction: The All of Us Research Program is funded by the National Institutes of Health. The aim of the program is to gather data from at least 1 million people of diverse backgrounds living in the United States to accelerate research and improve health. The purpose of this article is to discuss the collaboration of the All of Us Research Program and the National Association of Hispanic Nurses (NAHN) to increase awareness of the All of Us Research Program in Latino communities. Method: A community-based education approach by NAHN chapters across the country was used. The Sprint 1 grant was funded to increase awareness in health care providers of Latino communities. The Sprint 2 grant was funded to increase awareness in Latino communities. Results: A total of 8 NAHN chapters were selected to disseminate the All of Us Research Program information. These initiatives reached more than 156,000 health care providers and the chapters participated in 31 community-based activities across the country reaching thousands of Latinos. Discussion: The collaboration between the All of Us Research Program and NAHN was instrumental in disseminating information to the Latino population. Developing trust in Latino communities is an essential component of program success.
The Net Promoter Scores with Friends and Family Test after four hand surgery procedures
Authors: Stirling Paul , Jenkins Paul J. , Clement Nicholas D. , Duckworth Andrew D. , McEachan Jane E. 
Published: December 2018

The Friends and Family Test, a variant of the Net Promoter Score, was adapted for the National Health Service to evaluate overall patient satisfaction and how likely patients are to recommend an intervention. It ranges from −100 to 100. Positive scores indicate good performance. This study quantifies the scores in 810 patients at a mean of 14 months following four common procedures. The score was 83 for trigger finger release ( n = 103), 68 for carpal tunnel decompression ( n = 467), 62 for surgery for Dupuytren’s disease ( n = 224) and 44 for ganglia excision ( n = 16). Our study indicates that these procedures are highly valued and are recommended by patients according to the Friends and Family Test. The results of the Friends and Family Test correlated well with postoperative functional improvement and satisfaction. We conclude from this study that a compound score based on the Friends and Family Test is a useful addition to traditional measures of patient satisfaction. Level of evidence: II
Quality of Cartilage Repair from Marrow Stimulation Correlates with Cell Number, Clonogenic, Chondrogenic, and Matrix Production Potential of Underlying Bone Marrow Stromal Cells in a Rabbit Model
Authors: Dwivedi Garima , Chevrier Anik , Alameh Mohamad-Gabriel , Hoemann Caroline D. , Buschmann Michael D. 
Published: December 2018

Objective Previous studies have shown that intrinsic behavior of subchondral bone marrow stem cells (BMSCs) is influenced by donors and locations. To understand the variability in cartilage repair outcomes following bone marrow stimulation, we tested the hypothesis that in vivo cartilage repair correlates with in vitro biological properties of BMSCs using a rabbit model. Methods Full-thickness cartilage defects were created in the trochlea and condyle in one knee of skeletally mature New Zealand White rabbits ( n = 8) followed by microdrilling. Three-week repair tissues were analyzed by macroscopic International Cartilage Repair Society (ICRS) scores, O’Driscoll histological scores, and Safranin-O (Saf-O) and type-II collagen (Coll-II) % stain. BMSCs isolated from contralateral knees were assessed for cell yield, surface marker expression, CFU-f, %Saf-O, and %Coll-II in pellet culture followed by correlation analyses with the above cartilage repair responses. Results In vivo cartilage repair scores showed strong, positive correlation with cell number, clonogenic, chondrogenic, and matrix production (Coll-II, GAG) potential of in vitro TGF-βIII stimulated BMSC cultures. Trochlear repair showed clear evidence of donor dependency and strong correlation was observed for interdonor variation in repair and the above in vitro properties of trochlear BMSCs. Correlation analyses indicated that donor- and location-dependent variability observed in cartilage repair can be attributed to variation in the properties of BMSCs in underlying subchondral bone. Conclusion Variation in cell number, clonogenic, chondrogenic, and matrix production potential of BMSCs correlated with repair response observed in vivo and appear to be responsible for interanimal variability as well as location-dependent repair.
Targeting elevated left ventricular end-diastolic pressure following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction – a phase one safety and feasibility study
Authors: Khan Arshad A , Davies Allan J , Whitehead Nicholas J , McGee Michael , Al-Omary Mohammed S , Baker David , Bhagwandeen Rohan , Renner Ian , Majeed Tazeen , Hatton Rachael , Collins Nicholas J , Attia John , Boyle Andrew J 
Published: December 2018

Introduction:
Elevated left ventricular end diastolic pressure (LVEDP) is an independent predictor of mortality and heart failure in patients with ST-segment elevation myocardial infarction (STEMI). Whether lowering elevated LVEDP improves outcomes remains unknown.

Methods:
This non-randomized, single blinded study with prospective enrolment and sequential group allocation recruited patients undergoing primary percutaneous coronary intervention for STEMI with LVEDP ⩾ 20 mmHg measured immediately after primary percutaneous coronary intervention. The intervention arm (n=10) received furosemide 40 mg intravenous bolus plus escalating doses of glyceryl trinitrate (100 µg per min to a maximum of 1000 µg) during simultaneous measurement of LVEDP. The control group (n=10) received corresponding normal saline boluses with simultaneous measurement of LVEDP (10 readings over 10 min). Efficacy endpoints were final LVEDP achieved, and the dose of glyceryl trinitrate needed to reduce LVEDP by ⩾ 20%. Safety endpoint was symptomatic hypotension (systolic blood pressure &lt; 90 mmHg).

Results:
From 1 April 2017 to 23 August 2017 we enrolled 20 patients (age: 64±9 years, males: 60%, n=12, anterior STEMI: 65%, n=13). The mean LVEDP for the whole cohort (n=20) was 29±4 mmHg (intervention group: 28±3 mmHg vs. control group: 31±5 mmHg; p=0.1). The LVEDP dropped from 28±3 to 16±2 mmHg in the glyceryl trinitrate + furosemide group (p &lt;0.01) but remained unchanged in the control group. The median dose of glyceryl trinitrate required to produce ⩾ 20% reduction in LVEDP in the intervention group was 200 µg (range: 100–800). One patient experienced asymptomatic decline in systolic blood pressure to below 90 mmHg. There was no correlation between LVEDP and left ventricular ejection fraction.

Conclusion:
The administration of glyceryl trinitrate plus furosemide in patients with elevated LVEDP following primary percutaneous coronary intervention for STEMI safely reduces LVEDP.
Safety and efficacy of an oncolytic viral strategy using bortezomib with ICE/R in relapsed/refractory HIV-positive lymphomas
Authors: Reid Erin G. , Looney David , Maldarelli Frank , Noy Ariela , Henry David , Aboulafia David , Ramos Juan Carlos , Sparano Joseph , Ambinder Richard F. , Lee Jeannette , Cesarman Ethel , Yahyaei Sara , Mitsuyasu Ronald , Wachsman William 
Published: December 2018

Abstract
HIV-associated lymphomas (HALs) have high rates of latent infection by gammaherpesviruses (GHVs). We hypothesized that proteasome inhibition would induce lytic activation of GHVs and inhibit HIV infectivity via preservation of cytidine deaminase APOBEC3G, improving lymphoma control. We tested this oncolytic and antiviral strategy by using bortezomib combined with ifosfamide, carboplatin, and etoposide (ICE) alone or with rituximab (ICE/R) in relapsed/refractory HAL. A 3+3 dose-escalation design was used with a 7-day lead-in period of single-agent bortezomib. Bortezomib was administered intravenously on days 1 and 8 of each cycle at 1 of 4 dose levels: 0.7, 1.0, 1.3, or 1.5 mg/m2. ICE began day 8 of cycle 1 and day 1 of subsequent cycles. Rituximab was included on day 1 of cycles 2 to 6 for CD20+ lymphomas. Twenty-three patients were enrolled. The maximum tolerated dose of bortezomib was not reached. Grade 4 toxicities attributable to bortezomib were limited to myelosuppression. Responses occurred in 17 (77%) of 22 patients receiving any protocol therapy. The 1-year overall survival was 57%. After bortezomib alone, both patients with Kaposi sarcoma herpesvirus (KSHV)–positive lymphoma had more than a 1-log increase in KSHV viral load. In 12 patients with Epstein-Barr virus (EBV)–positive lymphoma, median values of EBV viral load increased. Undetectable HIV viremia at baseline in the majority of patients limited evaluation of HIV inhibition. APOBEC3G levels increased in 75% of evaluable patients. Bortezomib combined with ICE/R in patients with relapsed/refractory HAL is feasible with response and survival comparing favorably against previously reported second-line therapies. Changes in GHV viral loads and APOBEC3G levels trended as hypothesized. This trial was registered at www.clinicaltrials.gov as #NCT00598169.