bluuebunny/crossref_metadata_2025_split huggingface dataset:
MCF2 is linked to a complex perisylvian syndrome and affects cortical lamination
Authors: Molinard-Chenu Aude , Fluss Joël , Laurent Sacha , Guipponi Michel , Dayer Alexandre G 
Published: August 2019

AbstractThe combination of congenital bilateral perisylvian syndrome (CBPS) with lower motor neuron dysfunction is unusual and suggests a potential common genetic insult affecting basic neurodevelopmental processes. Here we identify a putatively pathogenic missense mutation in the MCF2 gene in a boy with CBPS. Using in utero electroporation to genetically manipulate cortical neurons during corticogenesis, we demonstrate that the mouse Mcf2 gene controls the embryonic migration of cortical projection neurons. Strikingly, we find that the CBPS-associated MCF2 mutation impairs cortical laminar positioning, supporting the hypothesis that alterations in the process of embryonic neuronal migration can lead to rare cases of CBPS.
An integrative approach uncovers genes with perturbed interactions in cancers
Authors: Kobren Shilpa Nadimpalli , Chazelle Bernard , Singh Mona 
Published: August 2019

AbstractA major challenge in cancer genomics is to identify genes with functional roles in cancer and uncover their mechanisms of action. Here, we introduce a unified analytical framework that enables rapid integration of multiple sources of information in order to identify cancer-relevant genes by pinpointing those whose interaction or other functional sites are enriched in somatic mutations across tumors. Our accompanying method PertInInt combines knowledge about sites participating in interactions with DNA, RNA, peptides, ions or small molecules with domain, evolutionary conservation and gene-level mutation data. When applied to 10,037 tumor samples across 33 cancer types, PertInInt uncovers both known and newly predicted cancer genes, while simultaneously revealing whether interaction potential or other functionalities are disrupted. PertInInt’s analysis demonstrates that somatic mutations are frequently enriched in binding residues and domains in oncogenes and tumor suppressors, and implicates interaction perturbation as a pervasive cancer driving event.(Software at http://github.com/Singh-Lab/PertInInt.)
SHYBRID: A graphical tool for generating hybrid ground-truth spiking data for evaluating spike sorting performance
Authors: Wouters Jasper , Kloosterman Fabian , Bertrand Alexander 
Published: August 2019

AbstractSpike sorting is the process of retrieving the spike times of individual neurons that are present in an extracellular neural recording. Over the last decades, many spike sorting algorithms have been published. In an effort to guide a user towards a specific spike sorting algorithm, given a specific recording setting (i.e., brain region and recording device), we provide an open-source graphical tool for the generation of hybrid ground-truth data in Python. Hybrid ground-truth data is a data-driven modelling paradigm in which spikes from a single unit are moved to a different location on the recording probe, thereby generating a virtual unit of which the spike times are known. The tool enables a user to efficiently generate hybrid ground-truth datasets and make informed decisions between spike sorting algorithms, fine-tune the algorithm parameters towards the used recording setting, or get a deeper understanding of those algorithms.
Contingent worker and innovation performance in electronics manufacturing service industry
Authors: Chen Chun-Hsi Vivian , Yeh Pi-Wen , Madsen Jean 
Published: August 2019

PurposeThis study aims to explore the influences of contingent workers on organizations’ innovation performance and develop a framework examining how innovation performance benefits from the utilization of contingent workers. Built up on a strategic human resource (HR) flexibility model, the importance of coordination flexibility of contingent worker skills and behaviors is highlighted.Design/methodology/approachStructural equation modeling is used to test the proposed hypotheses by using data collected from 163 paired surveys in Taiwan. The results provide support on the hypotheses.FindingsThe findings in this study highlight the coordination flexibility of contingent worker skills and behaviors, adaptive capability and knowledge integration on innovation performance in highly competitive industries. This study provides evidence linking coordination flexibility of contingent worker skills and behaviors and organizational innovation performance, and can contribute to the strategic HR management literature.Originality/valueCoordination flexibility of contingent worker skills and behaviors contributes positively to innovation performance. According to the findings, managers should pay more attention on the contingent workers’ coordination practices to enhance organizational innovation performance in the manufacturing firms. In addition to the managerial implications, research limitations and future research directions are also discussed.
Multi-level approach for important component identification and reliability evaluation for complex system by survival signature
Authors: Ge Liling , Zhang Yingjie 
Published: August 2019

Purpose
The purpose of this paper is to identify the critical components of a complex system by using survival signature. First, a complex system is abstracted with varying scales and generates a multi-levels model. Then reliability evaluations can be conducted by survival signature from rough to fine for tracing and identifying them. Finally, the feasibility of the proposed approach is demonstrated by an actual production system.

Design/methodology/approach
The paper mainly applies a multi-level evaluating strategy for the reliability analysis of complex systems with components of multiple types. In addition, a multi-levels model of a complex system is constructed and survival signature also used for evaluation.

Findings
The proposed approach was demonstrated to be the feasibility by an actual production system that is used in the case study.

Research limitations/implications
The case study was performed on a system with simple network structure, but the proposed approach could be applied to systems with complex ones. However, the approach to generate the digraphs of abstraction levels for complex system has to be developed.

Practical implications
So far the approach has been used for the reliability analysis of a machining system. The approach that is proposed for the identification of critical components also can be applied to make maintenance decision.

Originality/value
The multi-level evaluating strategy that was proposed for reliability analysis and the identification of critical components of complex systems was a novel method, and it also can be applied as index to make maintenance planning.
Study on the research evolution of Nobel laureates 2018 based on self-citation network
Authors: Wen Fangfang 
Published: August 2019

PurposeScience is a continuum of experiences consisting of authors and their publications, and the authors’ experience is an integral part of their work that gets reflected through self-citations. Thus, self-citations can be employed in measuring the relevance between publications and tracking the evolution of research. The paper aims to discuss this issue.Design/methodology/approachBased on the bibliographic data obtained from Scopus, this study constructs and visualizes the self-citation networks of ten Nobel laureates 2018, in the fields of Physiology or Medicine, Physics, Chemistry and Economic Science, to demonstrate the evolving process of each laureate’s research across his or her scholarly career.FindingsStatistics indicate that prominent scientists, such as Nobel laureates, have also frequently cited their own publications. However, their self-cited rates are quite low. Self-citations constitute an indispensable part of the citation system but contribute little to authors’ scientific impact, regardless of artificial self-citations. Self-citation networks present a trajectory that shows the evolving process of research across a scientist’s long-term scholarly career. There are obvious differences in self-citation patterns and network structures of different laureates without a disciplinary difference observed. The structures of self-citation networks are significantly influenced by laureates’ productivity. In addition, it is laureates’ own research patterns and citation habits that lead to the diversified patterns and structures of self-citation networks.Research limitations/implicationsOnly scientific achievements presented in the form of publications are investigated and other kinds of scientific output, such as patents, are not included. Moreover, this approach is fit for scientists who have had a longer career and higher productivity.Originality/valueThis study proves the feasibility and effectiveness of self-citation analysis as a new way to examine research evolution.
A conceptual model for enterprise risk management
Authors: Almeida Rafael , Teixeira José Miguel , Mira da Silva Miguel , Faroleiro Paulo 
Published: August 2019

Purpose
The purpose of this paper is to ease the ISO 31000 standard understanding and provide mechanisms that allow organizations to adopt and adapt this standard to their reality.

Design/methodology/approach
The research methodology adopted in this research was the design science research methodology.

Findings
Key finding is that enterprise architecture (EA) models and EA tools can help reduce the complexity of the ISO 31000 standard and improve the communication between stakeholders.

Practical implications
The research proposal serves the purpose of supporting the evidence collection for an enterprise risk management (ERM) initiative in an as-was, as-is, or to-be perspective.

Originality/value
Traditional ERM efforts operate on silos, limiting the sharing of risk information and the achievement of an organization-wide view of risks. EA can provide a common way to model complex business systems, from the strategic level to implementation details. This paper proposes the use of an EA model and an EA tool (Atlas) to represent ISO 31000, allowing a better understanding on the value of assets that can be affected from the manifestation of some risks over time.
Utilising stakeholder theory for social marketing process evaluation in a food waste context
Authors: Hodgkins Samuel , Rundle-Thiele Sharyn , Knox Kathy , Kim Jeawon 
Published: August 2019

Purpose
Calls for theoretically informed interventions and a more reflexive stance are apparent in social marketing. Moving from a “prove” to “improve” mentality requires evaluations that learn from experience gained to identify improvements to inform future programme success. This paper considers the value of inclusion of stakeholders in process evaluation.

Design/methodology/approach
Two participant groups (n = 90, n = 182) and one key stakeholder group (n = 22) were surveyed in person, over the phone and online. Open-ended qualitative responses were analysed for recurring themes.

Findings
Key stakeholders contribute unique and valuable insight into programme implementation and engagement, expanding evaluation beyond participant feedback. Most notably, the process evaluation illuminated the engagement insight of programme volunteers, mid-level expansion opportunities offered by participating chefs and the perceived value of involvement across all stakeholder groups.

Research limitations/implications
The study is limited by a lack of systematic stakeholder identification and to a single context, namely food waste.

Practical implications
This paper affirms the importance of process evaluation and application of stakeholder theory to social marketing. These contributions suggest a widened focus for the widely accepted NSMC benchmark criteria which centre attention on the end users targeted for change. Stakeholders should be included in process evaluations given they contribute important and unique partnership insights.

Originality/value
This paper extends stakeholder theory use in social marketing providing showcasing potential for this approach to deliver a more reflexive stance.
Advertising cooperation of dual-channel low-carbon supply chain based on cost-sharing
Authors: Yu Chao , Wang Chuanxu , Zhang Suyong 
Published: August 2019

Purpose
This paper aims to analyze the impact of the cost coefficient of product emission reduction, coefficient of low-carbon product advertising effort cost, and sharing ratio of low-carbon product advertising effort cost on the profit of a dual-channel supply chain. After determining the best model and relevant influencing factors, the paper puts forward corresponding management inspirations and suggestions.

Design/methodology/approach
The paper opts for an exploratory study using Stackelberg game theory to construct a centralized decision-making (MC mode), a low carbon product advertising effort cost free sharing decentralized decision-making (SD model) and a low carbon product advertising effort cost sharing decentralized decision-making (JD model) game model. Through using optimization methods to get the equilibrium solution, the relevant management suggestions are obtained by comparison analysis.

Findings
The paper shows that the JD model is better than the SD model in terms of the profits of the manufacturer, retailer and supply chain, and the improvement of Pareto is realized. The proportion of cost sharing of low carbon product advertising effort is positively related to the wholesale price and direct influence coefficient of low carbon product advertising effort on channel, while negatively related to the retail price and the cross influence coefficient of low carbon product advertising effort on alternative channels. Under the JD model, the manufacturer can reduce advertising costs through improving the efficiency and pertinence of direct channel advertising and urging the retailer to do a better job in sales management to improve gross margin and require the retailer to increase advertising efficiency and pertinence of retail channel to reduce advertising costs of retail channel and other ways to increase their profits. The retailer can make use of its advantages closer with consumers to improve the efficiency and pertinence of advertising in the retail channel to raise the influence coefficient of advertising and reduce the advertising cost in the retail channel.

Originality/value
The innovations of this paper are listed as follows: First, it has considered advertising investment from both the manufacturer and the retailer simultaneously. Second, it has considered a low-carbon background to investigate cooperative advertising decision for low-carbon products. Third, it has considered the decision on the level of product emission reduction and the level of low-carbon product advertising effort investment simultaneously.
Overcoming imposter syndrome: the adventures of two new instruction librarians
Authors: Martinez Jessica , Forrey Meredith 
Published: August 2019

Purpose
New librarians rarely feel fully prepared for academic library instruction. This could be attributed to many factors in both Master of Library and Information Science programs and work environments. Imposter syndrome or imposter phenomenon is a common way this insecurity manifests. Imposter phenomenon, first defined in 1978, is an individual’s feeling that they will be exposed as a fraud, regardless of how qualified or knowledgeable they actually are. Throughout the first year as new instruction librarians, the authors tracked their experiences with instruction and the imposter phenomenon. This paper aims to illuminate how imposter phenomenon impacts library instruction, provide suggestions for individual librarians and identify what academic libraries can do institutionally to mitigate feelings of fraudulence among their employees.

Design/methodology/approach
This paper outlines the history and symptoms of imposter phenomenon, focusing on its presence in libraries. The authors draw on existing literature in psychology and library science, their own experience and a survey of 172 librarians. Suggestions for best practices for easing imposter phenomenon are then discussed based on the experiences of the authors and survey respondents.

Findings
This paper suggests several ways to ease the feelings of imposter phenomenon among those employed in academic libraries.

Research limitations/implications
This paper is based on the authors’ experiences, as well as a survey of 172 librarians. The survey was self-selecting, so the results may be skewed, but the themes apparent throughout the responses indicate that imposter phenomenon in libraries is pervasive and warrants further research.

Practical implications
The recommendations presented in this paper will provide new librarians and library administrators with concrete ways to identify and ameliorate imposter phenomenon among new instruction librarians.

Originality/value
Though imposter phenomenon has gained popular attention in wider society, extant research has not sufficiently addressed its role in the realm of academic library instruction. Given that most MLIS programs focus on theory rather than practice, finding ways to give new instruction librarians confidence in their positions is an area of research that warrants more exploration.
Self-help groups in India: challenges and a roadmap for sustainability
Authors: Nayak Akhaya Kumar , Panigrahi Prabin Kumar , Swain Biswanath 
Published: August 2019

Purpose
Self-help groups (SHGs) have widely been accepted by developing nations for their contribution to inclusive development. Despite its importance and the recognition of the same, SHGs and their members face several challenges. The purpose of this paper is to comprehensively investigate the inhibiting factors affecting the effectiveness of women SHGs. The paper also proposes a roadmap for all the self-help promoting institutions, such as banks, state and central government, and non-government organizations to address the challenges.

Design/methodology/approach
The study adopts an exploratory research design to undertake this applied research. It uses phenomenographic and interpretative approaches. Qualitative data have been collected from 24 members belonging to eight SHGs from the eastern Indian state of Odisha with the help of a semi-structured interview schedule. The result has been analyzed by using content analysis.

Findings
The study finds that SHG members in Odisha face several challenges in the form of financial bottlenecks, entrepreneurial obstacles, capacity-building impediments, mentor-ship challenges, socio-structural challenges and group dynamics.

Research limitations/implications
The study finds many unique and contextual inhibiting factors, which are valuable additions to the existing literature. At the same time, the result may not be applicable to other kinds of SHGs, such as Alcoholic Anonymous, as their nature, composition and deliverables are quite different from the SHG that the current study has taken into consideration.

Practical implications
The proposed roadmap would be useful to policymakers, non-government organizations and other agencies involved in the promotion and capacity building of SHGs operating in Odisha in particular and India in general.

Originality/value
The literature is mainly concerned with the impact evaluation of SHG programs. This study investigates the challenges faced by SHGs in a systematic way and provides a roadmap to address the same in a comprehensive way.
Teaching and talking about religion: strategies for teacher educators
Authors: Logan Kimberly R. , Hartwick James M.M. 
Published: August 2019

Purpose
The purpose of this paper is to outline arguments for addressing religion in social studies teacher education, including strategies teacher educators might use on how and why pre-service teachers should incorporate teaching about religion in their classes. Topics addressed are: issues surrounding pre-service teachers’ religious identities; teaching pre-service teachers about legal issues associated with religion in public school classrooms (e.g. teaching about religion vs teaching for religion, First Amendment rights and constraints); teacher education’s role in developing religious knowledge and the influence of religion in the disciplines that comprise the social studies; and an overview of strategies and resources that teacher educators can use with their pre-service teachers.

Design/methodology/approach
This paper provides a literature review and arguments for addressing religion in social studies teacher education. A lesson plan and resources for teacher educators are also provided.

Findings
Teaching and talking about religion can no longer be marginalized or ignored within social studies teacher education. Whether it be the importance of pre-service teachers’ religious identities, legal issues related to public schooling or the influence of religion across the social studies disciplines – religion matters to social studies teacher education. As the current social, political and cultural realities attest, the influence of religion appears to be more and more significant in our interconnected and interdependent world.

Originality/value
Religious literacy is a key part of civic competence and if social studies is viewed as a way to help prepare a more informed citizenry – and a way to teach and promote dialogue across difference – then social studies teacher educators must find a way to include religion in their courses. By doing so, teacher educators encourage pre-service teachers to examine how religious identity may influence their teaching, and also help develop religious literacy and an understanding of how religion is integral to the various social studies disciplines. Ultimately, this important and often ignored work in teacher education may foster cultural understandings that will lead to a more informed and respectful society.
The global citizen and religious position statements on climate change
Authors: Shuttleworth Jay M. , Wylie Scott 
Published: August 2019

Purpose
The purpose of this paper is to discuss opportunities to analyze religious position statements calling climate change action a moral imperative.

Design/methodology/approach
In a lesson suited for the secondary history classroom, students will analyze how religious leaders, theologians and ecological and religious academics use passages from sacred texts to establish a moral urgency to mitigate climate change.

Findings
After analyzing these interpretations of sacred writings from five global faiths (Hinduism, Judaism, Catholicism, Islam and Anglicanism), the lesson centers on a dialogical question, “How might climate change action be influenced by religious texts?”

Originality/value
Implications emphasize why social studies teachers should not teach climate change as a controversial issue.