bluuebunny/crossref_metadata_2025_split huggingface dataset:
Análise transdisciplinar do Banco Nacional de Perfis Genéticos: técnicas moleculares e aspectos jurídicos
Authors: Monteiro Samantha Lopes , Soares de Oliveira Ívna , André Amorim de Carvalho Tarcísio 
Published: June 2019

O uso de marcadores moleculares para a identificação humana é uma estratégia aplicada nas atividades forenses no Brasil. A criação de bancos de perfis genéticos é uma tendência mundial. É esperado que o uso de tais dados não somente facilite a investigação de casos criminais, mas também leve à redução da criminalidade. O presente artigo objetiva-se realizar uma análise transdisciplinar sobre o Banco Nacional de Perfis Genéticos (BNPG), abordando a funcionalidade dele, apresentando também as técnicas moleculares aplicadas, além de suscitar discussões jurídicas geradas com a implantação do banco de dados nacional. Trata-se de uma revisão bibliográfica exploratória que foi elaborada a partir de uma pesquisa realizada em bases de dados bibliográficos como SciELO, PubMed e JusBrasil. A conscientização da funcionalidade potencial dessa ferramenta poderá despertar o interesse de mais especialistas de ambas as áreas, biológica e jurídica, para que possam aperfeiçoá-la e, futuramente, desenvolver outras aplicações.Palavras-Chave: Identificação Humana; DNA Forense; Banco de Dados; Ciências Forenses; Lei 12.654/12. AbstractThe use of molecular markers for human identification is a strategy applied in forensic investigation in Brazil. The creation of DNA databases is a worldwide trend. It is expected that the use of such data will not only assist investigation of criminal cases, but also lead to reduced crime. The present article aims to carry out a transdisciplinary analysis about the Brazilian National Genetic Profile Database, addressing its functionality, presenting also applied molecular techniques, as well as raising legal discussions generated with the implementation of the national DNA database. It is an exploratory bibliographic review that was elaborated from a research carried out in bibliographic databases like SciELO, PubMed and JusBrasil. Awareness of the potential functionality of this tool may raise the interest of more specialists in both biological and legal areas so that they can improve it and promote it in the future.Keywords: Human Identification; Forensic DNA; Database; Forensic Science; Law 12.654/12.
Population Genome Sequencing of the Scab Fungal SpeciesVenturia inaequalis,Venturia pirina,Venturia aucupariaeandVenturia asperata
Authors: Le Cam Bruno , Sargent Dan , Gouzy Jérôme , Amselem Joëlle , Bellanger Marie-Noëlle , Bouchez Olivier , Brown Spencer , Caffier Valérie , De Gracia Marie , Debuchy Robert , Duvaux Ludovic , Payen Thibaut , Sannier Mélanie , Shiller Jason , Collemare Jérôme , Lemaire Christophe 
Published: June 2019

AbstractThe Venturia genus comprises fungal species that are pathogens on Rosaceae host plants, including V. inaequalis and V. asperata on apple, V. aucupariae on sorbus and V. pirina on pear. Although the genetic structure of V. inaequalis populations has been investigated in detail, genomic features underlying these subdivisions remain poorly understood. Here, we report whole genome sequencing of 87 Venturia strains that represent each species and each population within V. inaequalis. We present a PacBio genome assembly for the V. inaequalis EU-B04 reference isolate. The size of selected genomes was determined by flow cytometry, and varied from 45 to 93 Mb. Genome assemblies of V. inaequalis and V. aucupariae contain a high content of transposable elements (TEs), most of which belong to the Gypsy or Copia LTR superfamilies and have been inactivated by Repeat-Induced Point mutations. The reference assembly of V. inaequalis presents a mosaic structure of GC-equilibrated regions that mainly contain predicted genes and AT-rich regions, mainly composed of TEs. Six pairs of strains were identified as clones. Single-Nucleotide Polymorphism (SNP) analysis between these clones revealed a high number of SNPs that are mostly located in AT-rich regions due to misalignments and allowed determining a false discovery rate. The availability of these genome sequences is expected to stimulate genetics and population genomics research of Venturia pathogens. Especially, it will help understanding the evolutionary history of Venturia species that are pathogenic on different hosts, a history that has probably been substantially influenced by TEs.
Mitochondrial Network State Scales mtDNA Genetic Dynamics
Authors: Aryaman Juvid , Bowles Charlotte , Jones Nick S , Johnston Iain G 
Published: June 2019

Abstract
Mitochondrial DNA (mtDNA) mutations cause severe congenital diseases but may also be associated with healthy aging. mtDNA is stochastically replicated and degraded, and exists within organelles which undergo dynamic fusion and fission. The role of the resulting mitochondrial networks in the time evolution of the cellular proportion of mutated mtDNA molecules (heteroplasmy), and cell-to-cell variability in heteroplasmy (heteroplasmy variance), remains incompletely understood. Heteroplasmy variance is particularly important since it modulates the number of pathological cells in a tissue. Here, we provide the first wide-reaching theoretical framework which bridges mitochondrial network and genetic states. We show that, under a range of conditions, the (genetic) rate of increase in heteroplasmy variance and de novo mutation are proportionally modulated by the (physical) fraction of unfused mitochondria, independently of the absolute fission–fusion rate. In the context of selective fusion, we show that intermediate fusion:fission ratios are optimal for the clearance of mtDNA mutants. Our findings imply that modulating network state, mitophagy rate, and copy number to slow down heteroplasmy dynamics when mean heteroplasmy is low could have therapeutic advantages for mitochondrial disease and healthy aging.
Krónikus orofacialis fájdalmak
Authors: Fehér Gergely , Nemeskéri Zsolt , Pusch Gabriella , Zádori Iván , Bank Gyula , Gurdán Zsuzsanna , Mészáros János , Mák Kornél , Tibold Antal , Komoly Sámuel 
Published: July 2019

Abstract: Orofacial pain is the common name of a variety of disorders from inflammatory diseases to neuropathic pain syndromes. This condition is quite common, it may involve 7% of the whole population. Patients (and doctors) are not aware of the origin of their complaints, therefore initial management falls among the variety of healthcare professionals. The aim of our review was to summarize the current evidence of chronic orofacial pain including diagnosis, management and pitfalls. Orv Hetil. 2019; 160(27): 1047–1056.
Az alsó ferde szemizom dozírozott transzpozíciójának hatásossága strabismus sursoadductorius esetén
Authors: Maneschg Otto Alexander , Knézy Krisztina , Maka Erika , Benyó Fruzsina , Sándor Gábor , Nagy Zoltán Zsolt 
Published: July 2019

Abstract: Introduction: Idiopathic strabismus sursoadductorius is characterized by an overaction of the inferior oblique (IO) muscle, with elevation of the eye in adduction. This can result in chronic headache, eye pain, diplopia and abnormal head posture. Aim: Presentation of clinical results after graded recession of inferior oblique overaction (IOOA) in strabismus sursoadductorius. Method: During a period of 6 years (2012–2017) we performed a dosed transposition of IO muscle in 53 patients in the Department of Ophthalmology of the Semmelweis University and analyzed the clinical results retrospectively. The mean age was 12.8, min–max: 2–51 years. The transposition of the muscle (8 mm, 10 mm or maximal) was performed because of IOOA and was planned depending on the vertical deviation (VD) in maximal adduction. In case of maximal transposition, the insertion of IO was placed under the lateral part of the lower rectus muscle. We evaluated the squint angle in five positions of gaze preoperatively and postoperative 1 week, 1 month and 3–6 months. We examined best corrected visual acuity, binocular vision and complications after surgery. Results: Postoperatively 25 patients had acceptable stereopsis (Titmus 5). Visual acuity remained stable after surgery in all cases. The VD measured in maximal adduction changed with a decrease of 7.5° when 8 mm transposition was performed, and changed with a decrease to 12°, when maximal recession was performed. The mean reduction of VD was 17.8 prism dioptres (PD) after 1 week (p<0.01), 20.5 PD after 1 month and remained stable during a follow-up of 3–6 months. Conclusion: Graded recession of inferior oblique muscle is a suitable proposed procedure in patients with marked strabismus sursoadductorius. The rates of functional under- or overcorrection or other complications are low. Orv Hetil. 2019; 160(27): 1064–1069.
Równi czy wspólnie? Kilka wątpliwości na temat równouprawnienia i jedna próba rozwiązania
Authors: Białkowska Monika 
Published: July 2019

At present the question of equality of women and men is non disputable. John Paul II spoke about it clearly and many times, but for most women his way of presentation of this issue was insufficient. Why? It seems that the use of the expression: „equal rights” is problematic in this context because it results in trading men against women and in proving that because we are equal, we are self-contained. This framework does not open us toward dialogue but it encloses us inside male and female worlds. Certainly it was not the intention of God, when He created us in His image and likeness as man and woman. Indeed we are His image if we are open to each other not only in mind and will but especially in the need of complementarity. Individually we can understand and recognize less than we can together so a meeting with the other sex is a chance for us to realize our potential as man and woman. For this reason, I propose to exchange the notion “equal right” for “co-rights”. It does not bring a category of identity but gives the criterion of reciprocity. In the Church the “co-rights” concept is more difficult to realize in practice than the demands of feminist theology. It requires from men not only the modification of their positions but the need of awareness that they do it for themselves and not only for women. Furthermore it demands from women courage and increasing levels of expertise. However, the starting point for both genders is humility.
Zmysł wiary jako zjawisko eklezjalne. Kontekst teologiczno-historyczny
Authors: Nadbrzeżny Antoni 
Published: July 2019

This paper discusses the issue of the sense of faith (sensus fidei) in the life of the Church. The author first describes the contemporary social context in which discussing the sensus fidei is meaningful. He then presents the nature of the sensus fidei and evaluates some major definitions of this concept. Emphasis is placed upon the biblical teaching on this spiritual gift and the milestones in the development of this idea. The author examines the manifestations of the sensus fidei in the personal life of the believer and in the communal life of the Church. He shows the living connection between the sensus fidei and the Magisterium Ecclesiae. The author concludes with his reflection on the dispositions needed by all believers for authentic participation in the sensus fidei. Ecumenical aspects of the sensus fidei still remain an important topic for Christian theologians. The relationship between the sensus fidei and public or majority opinion is a very delicate question. For that reason, the magisterium and theologians must constantly work to constitute the clear criteria for discernment of the authentic sensus fidei.
Three spectra problem for Stieltjes string equation and Neumann conditions
Authors: Dudko Anastasia , Pivovarchik Vyacheslav 
Published: June 2019

Spectral problems are considered which appear in description of small transversal vibrations of Stieltjes strings. It is shown that the eigenvalues of the Neumann-Neumann problem, i.e. the problem with the Neumann conditions at both ends of the string interlace with the union of the spectra of the Neumann-Dirichlet problems, i.e. problems with the Neumann condition at one end and Dirichlet condition at the other end on two parts of the string. It is shown that the spectrum of Neumann-Neumann problem on the whole string, the spectrum of Neumann-Dirichlet problem on the left part of the string, all but one eigenvalues of the Neumann-Dirichlet problem on the right part of the string and total masses of the parts uniquely determine the masses and the intervals between them.
Про структуру матриць над областю головних ідеалів відносно перетворення подібності
Authors: Прокіп Володимир 
Published: June 2019

В статті дослiджується структура матриць над областю головних iдеалiв вiдносно перетворення подiбностi. В другому розділі наведено допоміжні результати. В цьому розділі вказано трикутну формуматрицi відносно перетворення подібності, мінімальний многочлен якої розкладається в добуток різних лінійних множників. В розділі 3 доведено, що форма Хессенберга матриці A з незвідним мінімальним квадратичним многочленом m(λ) є блочно-трикутна матриця з блоками вимірності 2х2 на головній діагоналі та з характеристичними многочленами m(λ). У четвертому розділі доведено, що матриця A із мінімальним многочленом m (λ) = (λ-α) (λ-β), α ≠ β подібна нижній блочно-трикутній матриці, діагональними блоками якої є діагональні матриці з елементами α i β на головних діагоналях відповідно. Як наслідок вказано канонічну форму інволютивної матриці над кільцем цілих чисел відносно перетворень подібності.
A Physics-Based Estimation of Mean Curvature Normal Vector for Triangulated Surfaces
Authors: Das Sudip Kumar , Cenanovic Mirza , Zhang Junfeng 
Published: June 2019

In this note, we derive an approximation for the mean curvature normal vector on vertices of triangulated surface meshes from the Young-Laplace equation and the force balance principle. We then demonstrate that the approximation expression from our physics-based derivation is equivalent to the discrete Laplace-Beltrami operator approach in the literature. This work, in addition to providing an alternative expression to calculate the mean curvature normal vector, can be further extended to other mesh structures, including non-triangular and heterogeneous meshes.
Effects of Instructor Gender, Visual, and Auditory Melodic Recorded Instruction on Sequential Working Memory Recall in Individuals with and without Autism Spectrum Disorder
Authors: Schwartzberg Edward Todd , Silverman Michael J 
Published: June 2019

There is a lack of empirical inquiry concerning the effect of the therapist’s gender and aspects of visual and auditory melodic instruction on working memory recall in individuals with Autism Spectrum Disorder (ASD). The purpose of this study was to examine the effects of instructor gender and visual and auditory melodic instruction on working memory in individuals with ASD. Participants (n = 38 individuals with ASD and n = 18 neurotypical [NT] university students) viewed or listened to four melodic sequences of seven randomized monosyllabic words sung by female and male instructors. To assess working memory, participants’ tasks were to sequentially recall the paired information presented within each condition. There was no significant within-group difference between both the male and female instructor conditions or the visual + auditory or auditory only melodic instruction. Although not significant, participants tended to have slightly higher mean recall for the male instructor with visual + auditory stimuli condition and lower mean recall for the female instructor with auditory only stimuli condition. There was a significant between-group difference with the NT group having greater recall accuracy than the ASD group. Regardless of group or condition, participants tended to have greater recall accuracy at primary and recency serial positions. As individuals with ASD may have unique learning challenges, information paired with music may be delivered in multi-sensory ways to increase the likelihood of recall and subsequent learning. Implications for clinical practice, limitations of the study, and suggestions for future research are provided.
Eğitim Kaynaklarının Kullanım Etkinliği Üzerine Bir Uluslararası Karşılaştırma
Authors: ERDEM-KARA Başak , TAT Osman 
Published: June 2019

İlk
olarak 2003 yılında uygulanan ve sonraki her üç yılda bir tekrarlanan
Uluslararası Öğrenci Değerlendirme Programı (PISA) sonuçları öğrencilerin bilgi
ve beceri düzeylerinin ülkeler arasında karşılaştırılmasında, eğitim
politikalarının belirlenmesinde ve eğitim sistemlerinin güçlü ve zayıf
yönlerinin ortaya konmasında kullanılan oldukça kapsamlı göstergelerdir.
Uluslararası Öğrenci Değerlendirme Programı’nda öğrencilerin farkı alanlara
ilişkin performansları ölçülürken aynı zamanda katılımcı ülkelerin eğitimini
etkileyen alt yapı ve insan kaynakları gibi birçok girdiye ait veri de
toplanmaktadır. Bu çalışmada,
Uluslararası Öğrenci Değerlendirme Programı’nın son üç dönemine göre
Türkiye’nin, eğitim kaynaklarını etkin kullanımı bakımından Ekonomik Kalkınma
ve İş birliği Örgütü (OECD) üyeleri içerisindeki konumu, etkinlik oranının
yıllar içerisindeki değişimi veri zarflama analizi yardımı ile incelenmiştir.
Ayrıca Türkiye’nin hangi girdilerde nasıl bir değişikliğe gitmesi gerektiği
incelenmiştir. Araştırmada Uluslararası Öğrenci Değerlendirme Programı’nın
2009, 2012 ve 2015 dönemlerine katılan OECD ülkelerinin öğrenci test sonuçları
ve okul anketi verileri kullanılmıştır. Araştırma sonucunda, Türkiye’nin her üç
dönemde de kaynaklarını etkin kullanamadığı ve etkin kullanma oranının genel OECD
ortalamasının belirgin bir biçimde altında olduğu belirlenmiştir. Ayrıca
Türkiye’nin etkinlik oranının 2015 uygulamasında oldukça düştüğü tespit
edilmiştir. Her üç dönem için de Türkiye’nin öğrenci/öğretmen oranını düşürmesi
gerektiği sonucuna ulaşılmıştır.
DAMPAK PROGRAM PELATIHAN TERHADAP TINGKAT KOMPETENSI TEKNIS PEGAWAI
Authors: Mulyono Teguh , Meilani Rini Intansari 
Published: July 2019

Keunggulan sebuah institusi dalam mencapai setiap target yang telah ditetapkan, dipengaruhi, salah satunya, oleh tingkat kompetesi para pegawainya. Berbasis data penelitian survey yang diperoleh dari 32 orang pegawai pada sebuah institusi pemerintahan, artikel ini membahas hasil penelitian yang ditujukan untuk mengetahui dampak dari program pelatihan terhadap tingkat kompetensi teknis pegawai. Hasil analisa data menunjukan bahwa program pelatihan berpengaruh positif terhadap kompetensi teknis terutama dalam hal kemampuan berpikir, mempengaruhi, mengelola, berprestasi dan bertindak. Untuk mengoptimalkan kompetensi teknis para pegawai, setiap elemen dalam program pelatihan terutama metode pelatihan, harus di rancang agar menarik, inovatif, dan sesuai dengan kebutuhan para pegawai dalam melaksanakan tugas dan fungsinya.Kata Kunci : program pelatihan, kompetensi teknis THE IMPACT OF TRAINING PROGRAM ON EMPLOYEES’ COMPETENCY LEVELSThe success of an institution in meeting each of the targets it has set is affected, among others, by the competency level of its employees. Based on data of survey research to 32 employees of a government institution, this article discusses the findings of the research aimed to find about the impact of training program on the technical employees’ competency levels, especially in thinking skills, influencing others, competency levels of employees. The findings show that training program has a positive effect on managing, achieving, and taking action. To optimize the technical competency of employees, each element in the training program, ultimately the method, should be designed attractively and innovatively and in accordance with the needs of the employees in fulfilling their duties and functions. Keywords: trainingprogram, technical competency
IKLIM ORGANISASI DAN MOTIVASI KERJA SEBAGAI DITERMINAN KINERJA PEGAWAI
Authors: Shafarila Asri Wahyuni , Supardi Endang 
Published: July 2019

The purpose of this study was to analyze influence work climate and work motivation to employees performance. This research used explanatory survey method. Data collection techniques used question form with rating scale model on scale of 1-5. Respondents are structural employees Department of Education and Culture in one of the cities in West Java. Data were analyzed using regression. The result of the study revealed that work climate and work motivation both partially and simultaneously, has the positive and significant influence toward employees performance. Thus the temployee’s performance can be improved through increased work climate and work motivation. ABSTRAKPenelitian ini bertujuan untuk menganalisis pengaruh iklim organisasi dan motivasi kerja terhadap kinerja pegawai. Metode penelitian menggunakan metode survey eksplanasi. Teknik pengumpulan data menggunakan angket model rating scale dengan skor yang terentang antara 1 sampai dengan 5. Responden adalah pegawai struktural Dinas Pendidikan dan Kebudayaan di salah satu Kota di Jawa Barat. Teknik analisis data menggunakan regresi. Hasil penelitian menunjukkan iklim dan motivasi kerja memiliki pengaruh yang positif dan signifikan terhadap kinerja pegawai, baik secara parsial maupun secara simultan. Dengan demikian kinerja pegawai dapat ditingkatkan melalui peningkatan iklim dan motivasi kerja.
Meningkatkan Disiplin Belajar Siswa melalui Manajemen Kelas
Authors: Sari Bella Puspita , Hadijah Hady Siti 
Published: July 2019

This article aimed to determine the implementation of classroom management on students’ learning discipline. The research method used Expalanatory Survey method with data collection technique used questionnaire. Respondents are 80 students grade eleventh from Office Administration major of a vocational high school in Lembang, selected by used sampling technique. Data were analyzed using regression. The result of the research revealed that: (1) the classroom management is in the quite effective category, (2) the students' learning discipline is in the moderate category, and (3) there is a significant influence of classroom management on students’ learning discipline. Therefore, students’ learning discipline can be improved through increased classroom management by teachers.ABSTRAKArtikel ini membahas hasil penelitian yang bertujuan untuk mengetahui gambaran pelaksanaan manajemen kelas dan disiplin belajar siswa serta ada tidaknya pengaruh manajemen kelas terhadap disiplin belajar siswa pada sebuah SMK di Lembang. Metode yang digunakan adalah Ekspalanatory Survey dengan teknik pengumpulan data menggunakan angket. Respondennya berjumlah 80 orang siswa kelas XI Administrasi Perkantoran yang dipilih dengan menggunakan teknik sampling. Analisis data menggunakan regresi sederhana. Hasil penelitian menunjukan bahwa: (1) manajemen kelas berada pada kategori cukup efektif, (2) disiplin belajar siswa berada pada kategori sedang, dan (3) terdapat pengaruh yang signifikan manajemen kelas terhadap disiplin belajar siswa, artinya disiplin belajar siswa dapat ditingkatkan melalui manajemen kelas yang dilakukan oleh guru.