bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Model Pembelajaran Berbasis Masalah terhadap Kemampuan Pemecahan Masalah Matematika Siswa Kelas XI IPA MA Negeri 1 Lubuklinggau
Authors: Luthfiana Maria , Yuliansyah Yuliansyah , Fauziah Anna 
Published: July 2018

This research issue is whether there is influence of problem-based learning model for mathematical problem solving ability of students grade XI IPA MA Negeri 1 Lubuklinggau ?. The method used is a true experimental design were carried out with the comparison group. The study population was all students in grade XI IPA MA Negeri 1 Lubuklinggau, which consists of 113 students. As an experimental class is a class XI IPA 3 as many as 36 students and a control class is the class XI IPA 2 were 38 students randomly selected. Data collected by the testing techniques in narrative form. Data were analyzed using t-test. Based on the results of t-test analysis on the level of significance α = 0.05, obtained t_hitung (6.80) > t_tabel (1.671), so that it can be concluded there is the influence of problem-based learning model for mathematical problem solving ability of students grade XI IPA MA Negeri 1 Lubuklinggau.

Keywords: Problem Based Learning, Problem Solving Ability Mathematics
Peningkatan Ketuntasan Hasil Belajar Matematika Menggunakan Model Cooperative Learning Tipe STAD melalui Pemanfaatan Alat Peraga
Authors: Winarto Bambang 
Published: July 2018

The aim of this research is to improve students' learning mastery. This research uses qualitative and quantitative descriptive approach and this type of research is classroom action research. Methods of data collection using observation, test and documentation. The results obtained in this study is the result of student learning. This shows that in teaching and learning activities with contextual learning the students become very active. While student's learning completeness classically in cycle I reach 77,5% increase in cycle II to 90% so that only some student who have not finished their study. This suggests that STAD type cooperative learning can be considered as a learning model used by teachers. The conclusion that can be drawn from the data analysis and discussion is by applying STAD type cooperative learning can improve student learning outcomes. Based on the results of data analysis and discussion of the results of research on the application of STAD learning on student learning outcomes, it can be concluded the application of these methods can attract students to follow the teaching and learning activities to the end of the lesson with a pleasant learning environment that can lead to increased student learning outcomes.
Keywords: Cooperative Learning, TYPE STAD, Learning Outcomes.
Characteristics and Outcomes of Patients with Systemic Lupus Erythematosus–associated Thrombotic Microangiopathy, and Their Acquired ADAMTS13 Inhibitor Profiles
Authors: Yue Cai , Su Jian , Gao Ruitong , Wen Yubing , Li Chao , Chen Gang , Zhang Xuan , Li Xuemei 
Published: July 2018

Objective.To investigate the characteristics and outcomes of patients with systemic lupus erythematosus (SLE)–associated thrombotic microangiopathy (TMA) based on their ADAMTS13 inhibitor profiles.Methods.The medical data of 31 SLE patients with clinically diagnosed TMA were analyzed. ADAMTS13 activity and ADAMTS13 inhibitor were measured in all patients.Results.TMA was attributable to active SLE in 19 patients. ADAMTS13 inhibitor and severe ADAMTS13 deficiency were detected in 6 of them. Patients with ADAMTS13 inhibitor (n = 6) exhibited a lower platelet count (7.3 ± 5.1 vs 25.0 ± 17.8 × 109/l, p = 0.005) and more prevalent central nervous system (CNS) involvement (100.0% vs 23.1%, p = 0.003) than patients without ADAMTS13 inhibitor (n = 13). Patients with ADAMTS13 inhibitor also had mild renal involvement characterized by a higher estimated glomerular filtration rate (112.7 ± 18.0 vs 21.6 ± 12.0, p < 0.001), lower proteinuria level [0.6 (0.2–2.5) vs 8.1 (5.2–14.0) g/d, p = 0.011], and lower mean arterial pressure (95.3 ± 13.6 vs 117.5 ± 13.1 mmHg, p = 0.008) than was observed in patients without ADAMTS13 inhibitor. All patients with ADAMTS13 inhibitor achieved complete remission within 18.6 ± 8.7 days, while 3 patients (23.1%) without ADAMTS13 inhibitor achieved complete remission during a median followup of 5.0 months, even though more patients in this group received therapeutic apheresis (100.0% vs 50.0%, p = 0.021). The chance of complete remission increased by 10.8-fold (HR 10.8, 95% CI 1.8–65.5, p < 0.001) when ADAMTS13 inhibitor was present in SLE-associated TMA.Conclusion.Acquired ADAMTS13 deficiency is associated with more severe thrombocytopenia and CNS involvement, mild renal involvement, rapid resolution, and relatively good treatment response in SLE-associated TMA.
Monitoring of Systemic Lupus Erythematosus Pregnancies: A Systematic Literature Review
Authors: McDonald Emily G. , Bissonette Lyne , Ensworth Stephanie , Dayan Natalie , Clarke Ann E. , Keeling Stephanie , Bernatsky Sasha , Vinet Evelyne 
Published: July 2018

Objective.Few data exist to guide the frequency and type of monitoring in systemic lupus erythematosus (SLE) pregnancies. A systematic literature review was performed to address this gap in the literature.Methods.A systematic review of original articles (1975–2015) was performed using Medline, Embase, and Cochrane Library. We included search terms for SLE, pregnancy, and monitoring. We also hand-searched reference lists, review articles, and grey literature for additional relevant articles.Results.The search yielded a total of 1106 articles. After removing 117 duplicates, 929 articles that were evidently unrelated to our topic based on title and/or abstract, and 7 that were in a language other than English or French, 53 articles were included for full-text review. Following a more in-depth review, 15 were excluded: 6 did not use any measure of SLE activity and 6 did not specifically address SLE monitoring in pregnancy; 1 case series, 1 review, and 1 metaanalysis were removed. Among the 38 included studies, presence of active disease, antiphospholipid (aPL) antibodies positivity, and abnormal uterine and umbilical artery Doppler studies predicted poor pregnancy outcomes. No studies evaluated an evidence-based approach to the frequency of monitoring.Conclusion.Few existing studies address monitoring for optimal care during SLE pregnancies. The available data imply roles for aPL antibodies measurement (prior to pregnancy and/or during the first trimester), uterine and umbilical artery Doppler studies in the second trimester, and following disease activity. Optimal frequency of monitoring is not addressed in the existing literature.
Psoriatic Arthritis Sonographic Enthesitis Instruments: A Systematic Review of the Literature
Authors: Elalouf Ofir , Bakirci Ureyen Sibel , Touma Zahi , Anderson Melanie , Kaeley Gurjit S. , Aydin Sibel Z. , Eder Lihi 
Published: July 2018

Objective.As part of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) ultrasound working group, we performed a systematic review of the literature to assess the evidence and knowledge gaps in scoring instruments of enthesitis in psoriatic arthritis (PsA).Methods.A systematic search of PubMed, EMBase, and Cochrane databases was performed. The search strategy was constructed to find original publications containing terms related to ultrasound, enthesitis, spondyloarthritis (SpA) or PsA. Data extraction focused on the properties of the sonographic enthesitis instruments used in each study following components of the Outcome Measures in Rheumatology (OMERACT) filter: feasibility, test-retest reliability, construct validity as related to clinical assessment of enthesitis, biomarkers of inflammation and imaging of enthesitis by other modalities, discriminative validity, and responsiveness to treatment.Results.Fifty-one of 310 identified manuscripts were included. Only 1 scoring instrument of enthesitis was specifically developed and validated in patients with PsA. Only 18 (35%) of the studies involved patients with PsA, while the remaining studies focused on SpA. In PsA, construct validity was assessed using biomarkers and clinical examination in 1 (2%) and 11 (21.5%) of the studies, respectively, whereas no studies used imaging for the same purpose. Only 2 (4%) of the studies assessed discriminative validity in PsA. Responsiveness to treatment was assessed in 7 studies, none of which included patients with PsA.Conclusion.Although sonographic enthesitis scoring instruments have been developed for SpA, only a few have been validated in PsA. None of them passed the OMERACT filter in patients with PsA. Additional research is required before endorsing a specific instrument for the assessment of enthesitis in patients with PsA.
Zoster after Cyclophosphamide for Systemic Lupus Erythematosus or Vasculitis: Incidence, Risk Factors, and Effect of Antiviral Prophylaxis
Authors: Garnier Camille , Ribes David , Chauveau Dominique , Huart Antoine , Pugnet Grégory , Adoue Daniel , Prevot Grégoire , Alric Laurent , Delobel Pierre , Derumeaux Hélène , Mengelle Catherine , Sailler Laurent , Moulis Guillaume 
Published: July 2018

Objective.To assess the incidence and the risk factors for zoster in patients exposed to intravenous cyclophosphamide (CYC) for systemic vasculitis or systemic lupus erythematosus (SLE), as well as the protective effect of prophylaxis by valacyclovir (VCV).Methods.This retrospective study included all adults treated by intravenous CYC for SLE or systemic vasculitis between 2011 and 2015 at Toulouse University Hospital, France. Zoster occurrence was recorded using medical chart review, laboratory data, and patient interviews. Univariate Cox models were computed to assess the risk factors for zoster and the protective effect of prophylaxis by VCV.Results.The cohort consisted of 110 patients (81 systemic vasculitis and 29 SLE). During a mean followup of 3.4 years after CYC initiation, 10 cases of zoster occurred, leading to an overall incidence of 27.9/1000 patient-years (95% CI 15.2–50.6); it was 59.4/1000 patients (95% CI 27.5–123.6) during the year after CYC initiation. Four patients experienced persistent postherpetic neuralgia. Probable risk factors were lymphopenia < 500/µl at CYC initiation (HR 5.11, 95% CI 0.94–27.93) and female sex (HR 4.36, 95% CI 0.51–37.31). The incidence was higher in patients with SLE (HR as compared with systemic vasculitis patients = 2.68, 95% CI 0.54–13.26). None of the 19 patients exposed to VCV during the followup developed zoster.Conclusion.The incidence of zoster is high in systemic vasculitis and in patients with SLE exposed to intravenous CYC. CYC may favor postherpetic neuralgia. Prophylaxis by VCV should be considered, particularly in cases of lymphopenia < 500/µl at CYC initiation and during the year after.
Les métamorphoses de la reconnaissance
Authors: Évrard Brigitte , Quazza Jean-Pierre 
Published: July 2018

On hésite à positionner l’âge adulte, qui s’étend de la fin de l’adolescence à l’extrême vieillesse, comme une catégorie similaire à celles de l’enfance et de l’adolescence. En effet, sa durée s’étend en général sur plusieurs décennies. De plus, il n’est pas certain que l’âge adulte puisse se ranger dans des catégories comparables, ou même prendre place dans la suite des « phases » décrites ci-dessus, ne serait-ce qu’au regard des théories qui sous-tendent la division de l’enfance en diverses phases développementales. Certains considèrent d’ailleurs que le développement s’achève avec l’entrée dans cet âge, et que s’ouvre alors une période dans laquelle les choix de vie sont d’une nature différente. D’autres considèrent à l’inverse que le développement ne s’arrête pas avec l’entrée dans l’âge adulte. C’est en particulier la thèse des tenants du « potentiel humain » (mouvement dans lequel nombre des analystes transactionnels des premières générations se sont reconnus), qui se traduit par une offre et une pratique du « développement personnel » tout au long de la vie.
L’évolution des savoirs chinois sur l’Afrique : internationalisation des espaces d’apprentissage et transformation des objets de recherche
Authors: Bassan Martina , Gabas Jean-Jacques 
Published: July 2018

Resumé L’intégration croissante des chercheurs chinois dans des formations et des réseaux internationaux, ainsi que la multiplication d’espaces d’études supérieures, de rencontres et de débats sur l’Afrique sont à l’origine d’échanges de savoirs et d’une diversification des contenus des productions scientifiques chinoises. Les recherches sur les questions de développement en Afrique sont particulièrement représentatives de cette tendance : à côté des sujets classiques en économie du développement (comme les analyses de filières), de nouvelles thématiques apparaissent telles que celles des politiques publiques et de la sécurité.
Des « puits burkinabè » en Haute Guinée : processus et enjeux de la circulation de savoirs techniques dans le secteur minier artisanal
Authors: Lanzano Cristiano , Arnaldi di Balme Luigi 
Published: July 2018

Resumé L’extraction artisanale de l’or en Afrique de l’Ouest mobilise des savoirs techniques et entraîne des innovations qui traversent les frontières, du fait de la mobilité des orpailleurs qui se déplacent rapidement entre les zones aurifères. Nous présentons ici le cas d’un site minier artisanal en Haute Guinée, situé dans une région où l’orpaillage a une histoire très ancienne et est régi par des institutions coutumières : l’afflux récent d’orpailleurs provenant de pays voisins – notamment le Burkina Faso – a facilité la diffusion de nouvelles techniques de creusage et de traitement du minerai. L’article traite des conséquences sociopolitiques de ces innovations : les recompositions institutionnelles, le rôle des savoirs dans la construction de l’allochtonie, et les différentes idées de « frontière » qui s’opposent face à la mobilité des orpailleurs.
« Il tète, mais il n’y a pas de lait ». Hiérarchisation et hybridation des savoirs sur le colostrum au Cambodge
Authors: Bureau-Point Ève , Candau Joël , Sim Kruy Leang 
Published: July 2018

Resumé Le terme scientifique « colostrum » correspond au lait sécrété par la mère avant et/ou après la naissance de l’enfant. Il précède le lait dit « transitionnel », puis « mature ». Au Cambodge, les mères ont longtemps jeté cette substance et donné de l’eau le temps d’avoir le lait transitionnel. Depuis les années 1990, avec le renforcement de la médicalisation de la santé maternelle et infantile dans le cadre de l’aide internationale et la libéralisation économique, les savoirs et les pratiques autour de l’allaitement se modifient. Cet article documente, à partir d’une étude ethnographique réalisée dans une maternité de Phnom Penh de septembre à décembre 2014, les savoirs en coprésence circulant sur le colostrum et les pratiques qui en découlent. Des savoirs d’origine biomédicale, sociofamiliale, expérientielle et mercantile circulent. Des mécanismes de hiérarchisation et d’hybridation se produisent, contribuant à des pratiques recomposées, inspirées par la multiplicité des savoirs en circulation.
Embeddings of Müntz Spaces in
Authors: Al Alam Ihab , Lefèvre Pascal 
Published: July 2018

AbstractIn this paper, we discuss the properties of the embedding operator $i_{\unicode[STIX]{x1D707}}^{\unicode[STIX]{x1D6EC}}:M_{\unicode[STIX]{x1D6EC}}^{\infty }{\hookrightarrow}L^{\infty }(\unicode[STIX]{x1D707})$, where $\unicode[STIX]{x1D707}$ is a positive Borel measure on $[0,1]$ and $M_{\unicode[STIX]{x1D6EC}}^{\infty }$ is a Müntz space. In particular, we compute the essential norm of this embedding. As a consequence, we recover some results of the first author. We also study the compactness (resp. weak compactness) and compute the essential norm (resp. generalized essential norm) of the embedding $i_{\unicode[STIX]{x1D707}_{1},\unicode[STIX]{x1D707}_{2}}:L^{\infty }(\unicode[STIX]{x1D707}_{1}){\hookrightarrow}L^{\infty }(\unicode[STIX]{x1D707}_{2})$, where $\unicode[STIX]{x1D707}_{1}$, $\unicode[STIX]{x1D707}_{2}$ are two positive Borel measures on [0, 1] with $\unicode[STIX]{x1D707}_{2}$ absolutely continuous with respect to $\unicode[STIX]{x1D707}_{1}$.
Phytochemical Composition and Antioxidant Activity of Petals of Six Rosa Species from Iran
Authors: Shameh Shahla , Hosseini Bahman , Alirezalu Abolfazl , Maleki Ramin 
Published: July 2018

Abstract
Background: The petals of Rosa species are used in the food industry and various traditional medicinal products, but few studies exist on the phytochemical composition and antioxidant activity of petals of Rosa L. species grown in Iran. Objective: Phytochemical characteristics and antioxidant activity and some phenolic compounds of petals of six Rosa L. species were studied. Methods: Total phenolic content, total flavonoid content, and antioxidant activity were determined using Folin–Ciocalteu reagent, aluminum chloride method, ferric-reducing antioxidant power (FRAP), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays, respectively. An HPLC system was used for quantitative analysis of phytochemical compounds. Hierarchical cluster analysis (HCA) and principal component analysis (PCA) were performed among the variables analyzed using Minitab software. Also, heat maps were used to visualize phytochemical characteristics and antioxidant activity in each species using GraphPad Prism software. Results: The amount of total phenol content, total flavonoid content, and antioxidant activity were in the range of 25.13–52.01 mg gallic acid equivalents/g dry weight (DW), 0.61–0.82 mg quercetin equivalents/g DW, 11.47–20.93 µmol Fe++/g DW (FRAP), and 31.66–74.44% (DPPH), respectively. The p-coumaric acid (647.28 μg/g DW) and chlorogenic acid (24.37–135.23 μg/g DW) were found to be the most abundant phenolic compounds in the extracts of rose petals. The HCA and PCA revealed three distinct categories of species based on phytochemical composition and antioxidant activity. Conclusions: These results showed that phytochemical characteristics of different rose species widely correlated with species type and are promising sources of natural antioxidants beneficial for use in the food or pharmaceutical industries. Highlights: Iran is one of the main centers for genetic diversity of Rosa L. The petals of Rosa species are used in the food industry and various traditional medicinal products, but few studies exist on the phytochemical composition and antioxidant activity of petals of Rosa L. species grown in Iran. Antioxidant activity and phytochemical compound of Six Rosa L. species petals grown in Iran were studied. Phenolic compounds in petals of Rosa were analyzed by HPLC. The color parameters, amount of total phenolic, total flavonoids, antioxidant activity and some individual phenolic compounds were significantly variable amongst Rosa species.
A Dual‐Salt Gel Polymer Electrolyte with 3D Cross‐Linked Polymer Network for Dendrite‐Free Lithium Metal Batteries
Authors: Fan Wei , Li Nian‐Wu , Zhang Xiuling , Zhao Shuyu , Cao Ran , Yin Yingying , Xing Yi , Wang Jiaona , Guo Yu‐Guo , Li Congju 
Published: July 2018

AbstractLithium metal batteries show great potential in energy storage because of their high energy density. Nevertheless, building a stable solid electrolyte interphase (SEI) and restraining the dendrite growth are difficult to realize with traditional liquid electrolytes. Solid and gel electrolytes are considered promising candidates to restrain the dendrites growth, while they are still limited by low ionic conductivity and incompatible interphases. Herein, a dual‐salt (LiTFSI‐LiPF6) gel polymer electrolyte (GPE) with 3D cross‐linked polymer network is designed to address these issues. By introducing a dual salt in 3D structure fabricated using an in situ polymerization method, the 3D‐GPE exhibits a high ionic conductivity (0.56 mS cm−1 at room temperature) and builds a robust and conductive SEI on the lithium metal surface. Consequently, the Li metal batteries using 3D‐GPE can markedly reduce the dendrite growth and achieve 87.93% capacity retention after cycling for 300 cycles. This work demonstrates a promising method to design electrolytes for lithium metal batteries.
Alcohol‐induced respiratory symptoms improve after aspirin desensitization in patients with aspirin‐exacerbated respiratory disease
Authors: Glicksman Jordan T. , Parasher Arjun K. , Doghramji Laurel , Brauer David , Waldram Jeremy , Walters Kristen , Bulva Jeff , Palmer James N. , Adappa Nithin D. , White Andrew A. , Bosso John V. 
Published: July 2018

BackgroundAspirin‐exacerbated respiratory disease (AERD) is characterized by chronic eosinophilic rhinosinusitis, nasal polyps, asthma, and respiratory sensitivity to aspirin and nonsteroidal anti‐inflammatory drugs (NSAIDs). In addition to sensitivity to aspirin and NSAIDs, the majority of patients with AERD have been reported to have respiratory intolerance associated with the consumption of alcohol.MethodsA multicenter prospective cohort study was performed. Patients with AERD confirmed by aspirin challenge were eligible to participate. Those who described themselves as able to tolerate alcohol consumption were excluded. Patients underwent aspirin desensitization following endoscopic sinus surgery. A questionnaire was distributed to patients before and after desensitization to determine pre‐desensitization and post‐desensitization symptoms associated with alcohol ingestion.ResultsForty‐five patients were enrolled and 37 patients completed the study. The most common pre‐desensitization symptoms were nasal congestion (95.6%), rhinorrhea (46.7%), and wheezing (40%). Improvement in the ability to tolerate alcohol was noted in 86.5% of participants (95% confidence interval [CI], 75.5% to 97.5%) and 70.3% of participants (95% CI, 55.5% to 85.0%) described desensitization to be “very helpful” or “extremely helpful” for their ability to tolerate alcohol.ConclusionThe majority of patients with AERD who experience respiratory symptoms with alcohol consumption describe improvement in this domain following aspirin desensitization.
Degradation of Single‐Layer and Few‐Layer Graphene by Neutrophil Myeloperoxidase
Authors: Kurapati Rajendra , Mukherjee Sourav P. , Martín Cristina , Bepete George , Vázquez Ester , Pénicaud Alain , Fadeel Bengt , Bianco Alberto 
Published: July 2018

AbstractBiodegradability of graphene is one of the fundamental parameters determining the fate of this material in vivo. Two types of aqueous dispersible graphene, corresponding to single‐layer (SLG) and few‐layer graphene (FLG), devoid of either chemical functionalization or stabilizing surfactants, were subjected to biodegradation by human myeloperoxidase (hMPO) mediated catalysis. Graphene biodegradation was also studied in the presence of activated, degranulating human neutrophils. The degradation of both FLG and SLG sheets was confirmed by Raman spectroscopy and electron microscopy analyses, leading to the conclusion that highly dispersed pristine graphene is not biopersistent.
The Structure of [HSi9]3− in the Solid State and Its Unexpected Highly Dynamic Behavior in Solution
Authors: Lorenz Corinna , Hastreiter Florian , Hioe Johnny , Lokesh N. , Gärtner Stefanie , Korber Nikolaus , Gschwind Ruth M. 
Published: July 2018

AbstractWe report on the first unambiguous detection of the elusive [HSi9]3− anion in solutions of liquid ammonia by various 29Si and 1H NMR experiments including chemical exchange saturation transfer (CEST). The characteristic multiplicity patterns of both the 29Si and 1H resonances together with CEST and a partially reduced 1H,29Si coupling constant indicate the presence of a highly dynamic Si8 entity and a Si−H moiety with slow proton hopping. Theoretical calculations corroborate both reorganization of Si8 on the picosecond timescale via low vibrational modes and proton hopping. In addition, in a single‐crystal X‐ray study of (K(DB[18]crown‐6))(K([2.2.2]crypt))2[HSi9]⋅8.5 NH3, the H atom was unequivocally localized at one vertex of the basal square of the monocapped square‐antiprismatic cluster. Thus experimental studies and theoretical considerations provide unprecedented insight into both the structure and the dynamic behavior of these cluster anions, which hitherto had been considered to be rigid.