bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design of a t‐chart using generalized multiple dependent state sampling
Authors: Aslam Muhammad , Raza Muhammad Ali , Ahmad Liaquat , Jun Chi‐Hyuck 
Published: April 2019

AbstractIn this article, a new t‐chart based on generalized multiple dependent state (GMDS) sampling is proposed for efficient monitoring of a process by assuming that the time between events follows the exponential distribution. The proposed t‐chart has two pair of control limits and utilizes the past sample information with the current sample information. The control chart coefficients are estimated by considering different values of the in‐control average run lengths. The proposed t‐chart is compared with the existing chart by using the out‐of‐control average run length and extra quadratic loss function. The comparison reveals that the proposed charting strategy has better shift detection ability in process mean. An illustrative example is given for the practical implementation of the proposed chart.
Mixed Fluorinated/Hydrogenated Self‐Assembled Monolayer‐Protected Gold Nanoparticles: In Silico and In Vitro Behavior
Authors: Marson Domenico , Guida Filomena , Şologan Maria , Boccardo Silvia , Pengo Paolo , Perissinotto Fabio , Iacuzzi Valentina , Pellizzoni Elena , Polizzi Stefano , Casalis Loredana , Pasquato Lucia , Pacor Sabrina , Tossi Alessandro , Posocco Paola 
Published: April 2019

AbstractGold nanoparticles (AuNPs) covered with mixtures of immiscible ligands present potentially anisotropic surfaces that can modulate their interactions at complex nano–bio interfaces. Mixed, self‐assembled, monolayer (SAM)‐protected AuNPs, prepared with incompatible hydrocarbon and fluorocarbon amphiphilic ligands, are used here to probe the molecular basis of surface phase separation and disclose the role of fluorinated ligands on the interaction with lipid model membranes and cells, by integrating in silico and experimental approaches. These results indicate that the presence of fluorinated amphiphilic ligands enhances the membrane binding ability and cellular uptake of gold nanoparticles with respect to those coated only with hydrogenated amphiphilic ligands. For mixed monolayers, computational results suggest that ligand phase separation occurs on the gold surface, and the resulting anisotropy affects the number of contacts and adhesion energies with a membrane bilayer. This reflects in a diverse membrane interaction for NPs with different surface morphologies, as determined by surface plasmon resonance, as well as differential effects on cells, as observed by flow cytometry and confocal microscopy. Overall, limited changes in monolayer features can significantly affect NP surface interfacial properties, which, in turn, affect the interaction of SAM‐AuNPs with cellular membranes and subsequent effects on cells.
Representations of nature of science in U.S. science standards: A historical account with contemporary implications
Authors: Summers Ryan , Alameh Sahar , Brunner Jeanne , Maddux John M. , Wallon Robert C. , Abd‐El‐Khalick Fouad 
Published: April 2019

AbstractThis study evaluated the representations of nature of science (NOS) in U.S. state science standards, and examined the changes in these representations from documents advanced in the 1980s through 2016. Drawing from the consensus perspective on NOS and prior studies focusing on the analysis of textual content, documents were inspected for 10 target NOS aspects: the empirical, tentative, inferential, creative, theory‐driven, and social NOS, in addition to the myth of “The Scientific Method,” the nature of scientific theories and laws, and the social and cultural embeddedness of science. Ninety‐eight state documents from 48 states were analyzed and multiple editions were collected from 34 states. Additionally, relevant materials from the Next Generation Science Standards (NGSS) were assessed for their coverage of the same NOS aspects. Collected materials were scored as whole documents, including over 11,000 pages of text in total, on each target aspect, which reflected the treatment (naïve vs. informed) of NOS in text and the manner of presentation (explicit vs. implicit). Overall, surprisingly, state standards documents have improved very little with respect to their NOS coverage over the last 30 years. NOS standards documents remain silent on a majority of key aspects of NOS, and the number of aspects showing explicit, informed representations has held constant. The NGSS performed well compared to many contemporary documents, but they failed to address all target NOS aspects in a desirable manner. Further analysis raised concerns with the degree that states fully adopt and disseminate standards in manner consistent with the NGSS despite stated intentions, which may negatively impact NOS coverage in instructional resources and classroom enactments. To improve NOS representations in standards, recognizing the role these documents play in shaping instructional materials and teaching in the science classroom, exemplars from analyzed materials were highlighted with informed and explicit representations of multiple aspects.
Questions of life and death: (De)constructing human rights norms through US public opinion surveys
Authors: Nylen Alexandria , Carpenter Charli 
Published: April 2019

AbstractPublic opinion polls on national security issues are often seen as indicators of the strength of international human rights norms. By contrast, we hypothesise that the very act of answering poll questions can weaken citizens’ understandings of important international human rights laws and norms in the very moment they are being measured. We ground this discussion empirically by analysing a new dataset of post-9/11 survey questions on two US national security policies at odds with international human rights norms: ‘enhanced interrogations’ and ‘targeted killing’. In so doing, we encourage a widened research agenda on how international legal and normative understandings are transmitted to the public through surveys. We conclude by highlighting substantive implications for norm scholars and policy implications for norm advocates.
The Ex-Factor: Attachment Anxiety and Social Comparisons Across Romantic Relationships
Authors: Hingorani Simran , Pinkus Rebecca T. 
Published: April 2019

AbstractIndividuals high in attachment anxiety often experience persistent negative self-perceptions and heightened sensitivity toward perceived relationship threats. These characteristics may extend into past romantic relationships. This study examined whether individual differences in attachment style predict self-evaluations and relationship social comparison frequency. Two hundred and fifty-nine individuals rated themselves, their partner, and their current partner's ex-partner (CPE) or their ex-partner's current partner (ECP) on several dimensions. Individuals high in attachment anxiety experienced more relationship uncertainty but were not less satisfied than individuals low in attachment anxiety. They also made more comparisons in general and to relationships involving an ex-partner, and viewed themselves less positively than they viewed their CPE/ECP. Findings are discussed with respect to the influence that past relationships might hold over anxiously attached individuals’ current relationships.
Wheeling and dealing behind closed doors: estimating the causal effect of transparency on policy evaluations using a survey experiment
Authors: Juhl Sebastian , Hilpert David 
Published: April 2019

AbstractThe Transatlantic Trade and Investment Partnership between the European Union and the US is highly technical. Still, the negotiations triggered large-scale protests among citizens with very diverse socioeconomic backgrounds. Why has a complex issue such an enormous mobilizing effect although the economic consequences are either unclear or favorable for the participating economies? We argue that the transparency of negotiations is an important consideration for people evaluating the negotiation outcome. Conducting a survey experiment, we show that non-transparent decision-making decreases citizens' appraisal of the agreementindependentof its outcome: A non-transparent negotiation is, on average, almost 16 percent less likely to find public approval than a transparent but otherwise identical agreement. Our findings have important implications for democratic decision-making.
What Explains Credible Apologies? A Comment on Yap' ‘Non-Electoral Responsiveness Mechanisms’
Authors: LOWRY ROBERT C. 
Published: April 2019

In a recent issue of this Journal Professor Yap asks whether and how governments in what she calls ‘less-democratic’ countries, that is those where elections are uncompetitive due to a lack of democratic safeguards or opposition parties, are held accountable for the effects of their policies on economic performance. She argues that governments in these countries have an interest in avoiding strife and inducing private actors to provide resources necessary for economic prosperity. Because of this, ‘when their economies are performing less than optimally, these governments tend to offer credible apologies in the same year to attenuate the potential labour disquiet and loss in production investment.’ Yap develops the concept of a credible apology as the joint occurrence of punishment of responsible actors or reparations to injured parties, and an increase in monitoring activity by non-government actors. She then presents evidence for South Korea for 1964–87 and Singapore and Malaysia for 1966–94 showing that, ceteris paribus, the tendency of production investment to decrease and strike activity to increase in years with high unemployment is offset if the government makes a credible apology.Yap is quite clear that she assumes a causal arrow running from poor economic performance to credible apologies. Indeed, such a causal relationship is necessary for the concept of accountability; the events that Yap classifies as credible apologies must be made in response to unsatisfactory economic performance in order for us to say that these governments are being held (or are holding themselves) accountable for the consequences of their policies.
Lag effect of climatic variables on dengue burden in India
Authors: Kakarla Satya Ganesh , Caminade Cyril , Mutheneni Srinivasa Rao , Morse Andrew P , Upadhyayula Suryanaryana Murty , Kadiri Madhusudhan Rao , Kumaraswamy Sriram 
Published: April 2019

AbstractDengue is a widespread vector-borne disease believed to affect between 100 and 390 million people every year. The interaction between vector, host and pathogen is influenced by various climatic factors and the relationship between dengue and climatic conditions has been poorly explored in India. This study explores the relationship between El Niño Southern Oscillation (ENSO), the Indian Ocean Dipole (IOD) and dengue cases in India. Additionally, distributed lag non-linear model was used to assess the delayed effects of climatic factors on dengue cases. The weekly dengue cases reported by the Integrated Disease Surveillance Program (IDSP) over India during the period 2010–2017 were analysed. The study shows that dengue cases usually follow a seasonal pattern, with most cases reported in August and September. Both temperature and rainfall were positively associated with the number of dengue cases. The precipitation shows the higher transmission risk of dengue was observed between 8 and 15 weeks of lag. The highest relative risk (RR) of dengue was observed at 60 mm rainfall with a 12-week lag period when compared with 40 and 80 mm rainfall. The RR of dengue tends to increase with increasing mean temperature above 24 °C. The largest transmission risk of dengue was observed at 30 °C with a 0–3 weeks of lag. Similarly, the transmission risk increases more than twofold when the minimum temperature reaches 26 °C with a 2-week lag period. The dengue cases and El Niño were positively correlated with a 3–6 months lag period. The significant correlation observed between the IOD and dengue cases was shown for a 0–2 months lag period.
“Bonjour” Welcome to Québec City
Authors: Charest Pierre M. 
Published: April 2019

The Microsopical Society of Canada and the LAC of Microscopy and
Microanalysis 2002 are very proud to welcome you in Québec City
for the MSA - MAS - MSC/SMC-IMS joint meeting that will take place for
the first time in Canada. This event will be a commemorative new experience
of science mixed with the “Joie de Vivre” of Québec
City. Founded in 1608 by French explorer Samuel de Champlain, Québec
City was the center of New France, which at the time extended from the St.
Lawrence River in the northeast right down to the Gulf of Mexico in the
south. By the end of the 19th century, Québec City had taken on many
of its current attributes: political capital, university town, center of
culture, tourist destination, and regional services and trade hub. The
city's old quarter was declared a world heritage site by UNESCO in
1985.Come to Québec, an American-style City with a French Attitude!
Recent Weakening in the Stratospheric Planetary Wave Intensity in Early Winter
Authors: Hu Dingzhu , Guo Yipeng , Guan Zhaoyong 
Published: April 2019

AbstractPrevious studies have reported that the tropospheric climate shifted around the 2000s, but the recent trend in the stratospheric wave intensity (SWI) is still unclear. The results in this study show that the SWI in December during 2001–2015 weakens, which is opposite to that during 1979–2000, implying a shift around the 2000s. The weakened SWI is dominated by its wave number‐1 component, which is related to the wave propagation impeded by the decreased refractive index at high latitudes and the weakened wave activity in the troposphere. Changes in refractive index are mainly contributed by changes in the meridional potential vorticity gradient via the barotropic term. This shift in the wave number‐1 waves leads to a shift in the stratospheric Arctic temperature, that is, warming (cooling) during 1979–2000 (2001–2015), implying that similar shifting phenomena may appear regardless of the continued greenhouse gas emissions.
Extreme Convective Storms Over High‐Latitude Continental Areas Where Maximum Warming Is Occurring
Authors: Houze Robert A. , Wang Jingyu , Fan Jiwen , Brodzik Stacy , Feng Zhe 
Published: April 2019

AbstractDeep convective storms play a key role in severe weather, the hydrological cycle, and the global atmospheric circulation. Historically, little attention has been paid to the intense convective storms in the high latitudes. These regions have been experiencing the largest increases of mean surface temperature over the last century. The Global Precipitation Measurement core satellite, which features a space‐borne Dual‐frequency Precipitation Radar providing near‐global coverage (65°S to 65°N), has made it possible to establish the occurrence of convective storms at high latitudes. Analysis of the three‐dimensional radar echoes seen by Global Precipitation Measurement over a 5‐year period (2014–2018) shows that extremely intense deep convective storms do occur often during the warm season (April–September) in the high‐latitude continents where the increase of surface temperature has been greatest. The associated thermodynamical environments suggest that high‐latitude extreme convection could be more common in a continually warming world.
A High‐Fidelity Benthic Stable Isotope Record of Late Cretaceous–Early Eocene Climate Change and Carbon‐Cycling
Authors: Barnet J. S. K. , Littler K. , Westerhold T. , Kroon D. , Leng M. J. , Bailey I. , Röhl U. , Zachos J. C. 
Published: April 2019

AbstractThe Late Cretaceous–Early Paleogene is the most recent period in Earth history that experienced sustained global greenhouse warmth on multimillion year timescales. Yet, knowledge of ambient climate conditions and the complex interplay between various forcing mechanisms are still poorly constrained. Here we present a 14.75 million‐year‐long, high‐resolution, orbitally tuned record of paired climate change and carbon‐cycling for this enigmatic period (~67–52 Ma), which we compare to an up‐to‐date compilation of atmospheric pCO2 records. Our climate and carbon‐cycling records, which are the highest resolution stratigraphically complete records to be constructed from a single marine site in the Atlantic Ocean, feature all major transient warming events (termed “hyperthermals”) known from this time period. We identify eccentricity as the dominant pacemaker of climate and the carbon cycle throughout the Late Maastrichtian to Early Eocene, through the modulation of precession. On average, changes in the carbon cycle lagged changes in climate by ~23,000 years at the long eccentricity (405,000‐year) band, and by ~3,000–4,500 years at the short eccentricity (100,000‐year) band, suggesting that light carbon was released as a positive feedback to warming induced by orbital forcing. Our new record places all known hyperthermals of the Late Maastrichtian–Early Eocene into temporal context with regards to evolving ambient climate of the time. We constrain potential carbon cycle influences of Large Igneous Province volcanism associated with the Deccan Traps and North Atlantic Igneous Province, as well as the sensitivity of climate and the carbon‐cycle to the 2.4 million‐year‐long eccentricity cycle.
Prognosis and improved outcomes in major depression: a review
Authors: Kraus Christoph , Kadriu Bashkim , Lanzenberger Rupert , Zarate Carlos A. , Kasper Siegfried 
Published: April 2019

AbstractTreatment outcomes for major depressive disorder (MDD) need to be improved. Presently, no clinically relevant tools have been established for stratifying subgroups or predicting outcomes. This literature review sought to investigate factors closely linked to outcome and summarize existing and novel strategies for improvement. The results show that early recognition and treatment are crucial, as duration of untreated depression correlates with worse outcomes. Early improvement is associated with response and remission, while comorbidities prolong course of illness. Potential biomarkers have been explored, including hippocampal volumes, neuronal activity of the anterior cingulate cortex, and levels of brain-derived neurotrophic factor (BDNF) and central and peripheral inflammatory markers (e.g., translocator protein (TSPO), interleukin-6 (IL-6), C-reactive protein (CRP), tumor necrosis factor alpha (TNFα)). However, their integration into routine clinical care has not yet been fully elucidated, and more research is needed in this regard. Genetic findings suggest that testing for CYP450 isoenzyme activity may improve treatment outcomes. Strategies such as managing risk factors, improving clinical trial methodology, and designing structured step-by-step treatments are also beneficial. Finally, drawing on existing guidelines, we outline a sequential treatment optimization paradigm for selecting first-, second-, and third-line treatments for acute and chronically ill patients. Well-established treatments such as electroconvulsive therapy (ECT) are clinically relevant for treatment-resistant populations, and novel transcranial stimulation methods such as theta-burst stimulation (TBS) and magnetic seizure therapy (MST) have shown promising results. Novel rapid-acting antidepressants, such as ketamine, may also constitute a paradigm shift in treatment optimization for MDD.
Differential Mobility Spectrometry of Ketones in Air at Extreme Levels of Moisture
Authors: Safaei Z. , Eiceman G. A. , Puton J. , Stone J. A. , Nasirikheirabadi M. , Anttalainen O. , Sillanpää M. 
Published: April 2019

AbstractThe performance of a differential mobility spectrometer was characterized at ambient pressure and ten values of water vapor concentration, from 1.0 × 102 to 1.7 × 104 ppm using a homologous series of seven ketones from acetone to 2-dodecanone. Dispersion plots at 30 °C with separation fields from 35 to 123 Td exhibited increased alpha functions for the hydrated proton, protonated monomers, and proton bound dimers with increased moisture levels. Increases in the level of moisture were accompanied by decreased quantitative response with progressive suppression in the formation of the proton bound dimer first and then protonated monomer. Product ions for 2-octanone at 7 ppb were not observed above a moisture level of 4.0 × 103 ppm, establishing a limit for observation of analyte ion formation. The observation limit increased from 1.1 × 103 ppm for acetone to 5.7 × 103 ppm for 2-dodecanone. These findings demonstrate that ketones can be determined with a differential mobility spectrometry (DMS) analyzer near room temperature in the presence of elevated levels of moisture expected with the use of membrane inlets or headspace sampling of surface or ground waters. Moisture levels entering this DMS analyzer employed as an environmental monitor should be kept at 1.0 × 103 ppm or below and quantitative studies for individual ketones should be made at a fixed moisture level.
Succession matters: Community shifts in moths over three decades increases multifunctionality in intermediate successional stages
Authors: Habel Jan Christian , Segerer Andreas H. , Ulrich Werner , Schmitt Thomas 
Published: April 2019

AbstractSpecies composition strongly depends on time, place and resources. In this context, semi-natural grasslands belong to the most species-rich habitats of Europe, and succession may eventually cause local extinction of typical grassland species, but conversely increase species richness due to habitat diversification. Here, we analyse potential effects of succession of calcareous grasslands on moths. Our studied community, assessed over three decades in south-eastern Germany, comprised >1000 species. We compiled data on the ecology of each of these species, considering the larval and adult stages. We assigned Ellenberg indicator values to each main larval food plant species used by these lepidopterans. Changes in the community means of these indicators were applied to test for possible consequences of the changes in habitat structure and quality. Our data revealed increasing multifunctionality of community structure, higher variability of habitat association over time, the appearance of range expanding species, but also local extinction of various typical grassland moth species. These shifts in species composition mirror effects of succession, which frequently transform previously homogenous semi-natural grasslands into a heterogeneous habitat mosaic.