bluuebunny/crossref_metadata_2025_split huggingface dataset:
Illusory Form Perception and Perceptual Grouping Operations under Conditions of Restricted Visual Awareness
Authors: Jimenez Mikel , Montoro Pedro R. 
Published: October 2018

AbstractIn the present study, we conducted two experiments (Experiment 1: 35 participants, M = 29; SD = 8.4; Experiment 2: 36 participants, M = 25; SD = 6.1) with the intention to explore whether underlying perceptual grouping operations and illusory form perception generate dissociable priming effects when Kanizsa-like figures are presented as primes and the rotated inducers as controls under conditions of restricted awareness. Using five different stimulus onset asynchronies (SOA conditions, Experiment 1: 27, 40 and 53 ms; Experiment 2: 27, 80 and 227 ms), we displayed masked illusory and groping primes that could be congruent or incongruent in their orientation with subsequent probe stimuli (vertical vs. horizontal). We found significant priming effects in both Experiment 1 and 2 (p < .001, η2p = .31 and p = .016, η2p = .16, respectively), but, crucially, no significant priming differences between illusory and grouping primes across SOA conditions. Overall, our results are important in showing that a dissociation of the percept generated by the grouping of the inducers from that generated by the illusory form is crucial in the study of illusory form perception under conditions of restricted awareness. In addition, they provide further evidence of perceptual organization operations occurring under very restrictive awareness conditions.
Culturally Relevant Meanings of the Protestant Work Ethic and Attitudes towards Poor Persons
Authors: Bernardo Allan B. I. , Levy Sheri R. , Lytle Ashley E. 
Published: October 2018

AbstractThe Protestant work ethic (PWE), or the belief that hard work leads to success, is a popular belief across cultures. Much work indicates that PWE contributes to negative evaluations of disadvantaged groups presumably through the notion that they deserve their disadvantage for not working hard enough (“PWE-Justifier”). But there is another dimension of PWE that expresses the belief that everyone could succeed through hard work (“PWE-Equalizer”). We propose that the PWE-Justifier is meaningful in cultures that emphasize individualism and personal responsibility, but not in others. In a cross-cultural study, we compare how PWE-Justifier relates to evaluations of poor persons in the USA (individualist culture) and the Philippines (low individualist culture). In the USA sample, regression analysis indicated that internal attributions of poverty mediated the relationships of PWE-Justifier with negative stereotypes (R2 = .32) and with negative attitudes towards poor persons (R2 = .13). Bootstrapping analysis indicated that both indirect effects of PWE-Justifier were significant: Negative stereotypes, B = .17, SE = .03, p < .0001, 95% CI [.11, .24]; negative attitudes, B = 2.52, SE = 1.11, p = .014, 95% CI [0.49, 4.84]. The results were not found in the Philippine sample, where instead, PWE-Equalizer negatively predicted negative attitudes (R2 = .05) and positively predicted empathy (R2 = .05) for poor persons. The results are discussed in terms of how the negative consequences of PWE may derive from the cultural syndrome of individualism that emphasizes personal control and responsibility.
On the Role of the Flaming to Smoldering Transition in the Seasonal Cycle of African Fire Emissions
Authors: Zheng Bo , Chevallier Frederic , Ciais Philippe , Yin Yi , Wang Yilong 
Published: October 2018

AbstractSatellite estimates of burned area, associated carbon monoxide (CO) emission estimates, and CO column retrievals do not agree on the peak fire month in Africa, evident in both Northern and Southern Africa though distinct in the burning seasonality. Here we analyze this long‐standing problem using (1) a top‐down Bayesian inversion of Measurements Of Pollution In The Troposphere CO columns during 2005–2016 into surface CO emissions and (2) the bottom‐up Global Fire Emissions Database 4.1 s. We show that Global Fire Emissions Database 4.1 s underestimates CO emissions by 12–62% in the late fire season and hypothesize that this is partly because it assumes seasonally static emission factors. However, the degree to which emission factors would have to vary through the season to bring top‐down and bottom‐up in agreement cannot be confirmed by past field‐based measurements. Improved observational constraint on the seasonality of burned area, fuel combustion, and emission factors would further reduce the discrepancy between bottom‐up and top‐down emission estimates.
Circulation Drivers of Atmospheric Rivers at the North American West Coast
Authors: Guirguis Kristen , Gershunov Alexander , Clemesha Rachel E. S. , Shulgina Tamara , Subramanian Aneesh C. , Ralph F. Martin 
Published: October 2018

AbstractAtmospheric rivers (ARs) are mechanisms of strong moisture transport capable of bringing heavy precipitation to the West Coast of North America, which drives water resources and can lead to large‐scale flooding. Understanding links between climate variability and landfalling ARs is critical for improving forecasts on timescales needed for water resource management. We examined 69 years of landfalling ARs along western North America using reanalysis and a long‐term AR catalog to identify circulation drivers of AR landfalls. This analysis reveals that AR activity along the West Coast is largely associated with a handful of influential modes of atmospheric variability. Interaction between these modes creates favorable or unfavorable atmospheric states for landfalling ARs at different locations, effectively steering moisture plumes up and down the coast from Mexico to British Columbia. Seasonal persistence of certain modes helps explain interannual variability of landfalling ARs, including recent California drought years and the wet winter of 2016/2017.
Generality of Hydrologic Transport Limitation of Watershed Organic Carbon Flux Across Ecoregions of the United States
Authors: Zarnetske Jay P. , Bouda Martin , Abbott Benjamin W. , Saiers James , Raymond Peter A. 
Published: October 2018

AbstractAlthough the flux of dissolved organic carbon (DOC) through freshwaters is nearly equivalent to the net carbon uptake of all terrestrial ecosystems, uncertainty remains about how source processes (carbon production and location) and transport processes (hydrologic connectivity and routing) interact to determine DOC flux across flow conditions and ecoregions. This limits our ability to predict the fluvial carbon flux responses to changes in climate and land use. We used DOC concentration and discharge patterns with ensemble modeling techniques to quantify DOC flux behavior for 1,006 U.S. watersheds spanning diverse climate and land cover conditions. We found that DOC flux was transport‐limited (concentration increased with discharge) in 80% of watersheds and that this flux behavior spanned ecoregions and watershed sizes. The generality of transport limitation demonstrates how coupling discharge models with widely available watershed properties could allow DOC flux to be efficiently integrated into landscape and Earth system models.
Representation of Model Error in Convective‐Scale Data Assimilation: Additive Noise, Relaxation Methods, and Combinations
Authors: Zeng Yuefei , Janjić Tijana , de Lozar Alberto , Blahak Ulrich , Reich Hendrik , Keil Christian , Seifert Axel 
Published: October 2018

AbstractFor ensemble data assimilation, background error covariance should account for sampling and model errors. There are a number of approaches that have been developed that try to consider these errors; among them, additive noise and relaxation methods (relaxation to prior perturbation and relaxation to prior spread) are often used. In this work, we compare additive noise, based on random samples from global climatological atmospheric background error covariance, to relaxation methods as well as combinations. Our experiments have been conducted in framework of convective‐scale data assimilation with conventional and radar reflectivity observations hourly assimilated for a 2‐week convective period over Germany. In the first week under weather conditions characterized by strong large‐scale forcing of convection, additive noise performs equally or even better than relaxation methods and combinations during both assimilation and short‐range forecasts. In addition, it is shown that the relaxation to prior perturbation may be associated with smoothing of background errors that negatively affect small‐scale structures and that the relaxation to prior spread yields more unbalanced model states. For the second week in absence of strong forcing, the performance of additive noise relative to combinations has been degraded a bit but results are still comparable. Overall, additive noise provides a good benchmark for further developments in representation of model error for convective‐scale data assimilation.
Multiple Proxy Estimates of Atmospheric CO2 From an Early Paleocene Rainforest
Authors: Kowalczyk Jennifer B. , Royer Dana L. , Miller Ian M. , Anderson Clive W. , Beerling David J. , Franks Peter J. , Grein Michaela , Konrad Wilfried , Roth‐Nebelsick Anita , Bowring Samuel A. , Johnson Kirk R. , Ramezani Jahandar 
Published: October 2018

AbstractProxy estimates of atmospheric CO2 are necessary to reconstruct Earth's climate history. Confidence in paleo‐CO2 estimates can be increased by comparing results from multiple proxies at a single site, but so far this strategy has been implemented only for marine‐based techniques. Here we present CO2 estimates for the well‐studied early Paleocene Castle Rock site in Colorado using four paleobotanical proxies. Median estimates range from 470 to 813 ppm, demonstrating fair correspondence. The synthesis yields a median of 616 ppm (352–1110 ppm at 95% confidence), considerably higher than previous early Paleocene CO2 estimates (~300 ppm). Ash bed geochronology by the high‐precision U‐Pb method places the Castle Rock assemblage at 63.844 ± 0.097 Ma (fully propagated 2σ error). When these results are placed into the broader context of other Cenozoic CO2 estimates from plant‐gas‐exchange approaches and coeval estimates of global mean surface temperature, a pattern emerges of an Earth system sensitivity around 3 °C per CO2 doubling during the Paleocene and Eocene, a time with little land ice, then steepening to >7 °C after the Eocene once land ice was present on Antarctica.
Environmental Conditions During the Reported Charging Anomalies of the Two Geosynchronous Satellites: Telstar 401 and Galaxy 15
Authors: Saiz E. , Cid C. , Guerrero A. 
Published: October 2018

AbstractCharging and subsequent electrostatic discharge is recognized as a serious operational threat to spacecraft. This paper concentrates on an analysis of the environmental conditions (geomagnetic measurables, but not the particle fluxes, that were associated with the geomagnetic disturbances) and the interplanetary signatures prior to the anomalies that affected the two geostationary satellites Telstar 401 and Galaxy 15, which were believed to have been caused by spacecraft charging/electrostatic discharge. In terms of geomagnetic conditions, the planetary Kp index was very different around the two events, despite Kp commonly being used to characterize periods that are hazardous for spacecraft charging. On the contrary, local geomagnetic records, both from GOES satellites and from ground records, reveal that each anomaly took place during the expansion phase of a triggered substorm. Combined with a large and south directed interplanetary magnetic field (IMF) Bz, northward turnings of negative IMF Bz and large fluctuations in IMF By played major roles in the magnetospheric responses of the substorms. The interplanetary features of the two events were also similar: the interplanetary counterpart of coronal mass ejections interacted with high‐speed streams, favoring the substorm triggers. Although there are several differences in the preconditioning and the inner conditions of the magnetosphere before the anomalies, in each case the respective spacecraft crossed the plasma sheet in the magnetotail during enhanced substorm activity, with a dipolarization event that took place close to the spacecraft location, indicating that each satellite was in the wrong place at a critical moment.
Real‐Time Detection of the Ground Level Enhancement on 10 September 2017 by A.Ne.Mo.S.: System Report
Authors: Mavromichalaki H. , Gerontidou M. , Paschalis P. , Paouris E. , Tezari A. , Sgouropoulos C. , Crosby N. , Dierckxsens M. 
Published: October 2018

AbstractOn 10 September 2017, a ground level enhancement (GLE) of cosmic ray intensity, identified as GLE72, was recorded by several stations of the worldwide neutron monitor network provided by the high‐resolution Neutron Monitor Database. The solar proton event that resulted in this GLE was associated with active region AR2673, which produced an X8.2 flare on the solar west limb. Protons were measured by the GOES satellites with energies above 10, 50, and 100 MeV, while particles at higher energies above 500 MeV were registered by ground‐based neutron monitors. This GLE event was successfully detected in real time by the GLE Alert plus System of the Athens Neutron Monitor Station (A.Ne.Mo.S.). In this work an overview of the GLE72 event is given, and a detailed analysis of the evolution of the GLE Alert signal issued by the GLE Alert plus System as well as a postevent summary are presented.
On the Little‐Known Consequences of the 4 August 1972 Ultra‐Fast Coronal Mass Ejecta: Facts, Commentary, and Call to Action
Authors: Knipp Delores J. , Fraser Brian J. , Shea M. A. , Smart D. F. 
Published: October 2018

AbstractToday the extreme space weather events of early August 1972 are discussed as benchmarks for Sun‐Earth transit times of solar ejecta (14.6 hr) and for solar energetic particle fluxes (10 MeV ion flux >70,000 cm−2·s−1·sr−1). Although the magnetic storm index, Dst, dipped to only −125 nT, the magnetopause was observed within 5.2 RE and the plasmapause within 2 RE. Widespread electric‐ and communication‐grid disturbances plagued North America late on 4 August. There was an additional effect, long buried in the Vietnam War archives that add credence to the severity of the storm impact: a nearly instantaneous, unintended detonation of dozens of sea mines south of Hai Phong, North Vietnam on 4 August 1972. The U.S. Navy attributed the dramatic event to magnetic perturbations of solar storms. Herein we discuss how such a finding is broadly consistent with terrestrial effects and technological impacts of the 4 August 1972 event and the propagation of major eruptive activity from the Sun to the Earth. We also provide insight into the solar, geophysical, and military circumstances of this extraordinary situation. In our view this storm deserves a scientific revisit as a grand challenge for the space weather community, as it provides space‐age terrestrial observations of what was likely a Carrington‐class storm.
On the Need to Automate Support for Quality Assessment Studies of Space Weather Models
Authors: MacNeice P. 
Published: October 2018

AbstractModel quality assessment (QA) and, where possible, model validation are critical steps in the life cycle of models destined to play a role in space weather research and forecasting. A major goal of QA is to characterize the state of the art of models of a given class, for example, models of the global corona and solar wind. This requires consistent assessment of all major models in the class. Commonly, QA has been done in what amounts to campaign mode, generating reports that capture the quality of a particular model or a limited set of models for specific events or time intervals. Inconsistencies between study designs, the limited scope of each study, and the intermittency with which the study reports appear in the literature mean that we never achieve a complete assessment of the state of the art. In addition, the time frame in which new models appear or existing models are upgraded is comparable to the publication time of peer‐reviewed validation reports, which means that these reports are often out of date soon after they are published. The community's current QA strategy is inadequate and unsustainable. In this paper we show why it is unsustainable and advocate for the development of automated protocols which can, with minimal ongoing labor cost, support the community's efforts to maintain up‐to‐date results. We illustrate the concept with results from a pilot scheme developed in conjunction with the Solar Heliospheric and Interplanetary Environment community.
Establishment of stably expandable induced myogenic stem cells by four transcription factors
Authors: Lee Eun-Joo , Kim Minhyung , Kim Yong Deuk , Chung Myung-Jin , Elfadl Ahmed , Ulah H. M. Arif , Park Dongsu , Lee Sunray , Park Hyun-Sook , Kim Tae-Hwan , Hwang Daehee , Jeong Kyu-Shik 
Published: October 2018

AbstractLife-long regeneration of healthy muscle by cell transplantation is an ideal therapy for patients with degenerative muscle diseases. Yet, obtaining muscle stem cells from patients is very limited due to their exhaustion in disease condition. Thus, development of a method to obtain healthy myogenic stem cells is required. Here, we showed that the four transcription factors, Six1, Eya1, Esrrb, and Pax3, converts fibroblasts into induced myogenic stem cells (iMSCs). The iMSCs showed effective differentiation into multinucleated myotubes and also higher proliferation capacity than muscle derived stem cells both in vitro and in vivo. The iMSCs do not lose their proliferation capacity though the passaging number is increased. We further isolated CD106-negative and α7-integrin-positive iMSCs (sort-iMSCs) showing higher myogenic differentiation capacity than iMSCs. Moreover, genome-wide transcriptomic analysis of iMSCs and sort-iMSCs, followed by network analysis, revealed the genes and signaling pathways associated with enhanced proliferation and differentiation capacity of iMSCs and sort-iMSCs, respectively. The stably expandable iMSCs provide a new source for drug screening and muscle regenerative therapy for muscle wasting disease.
circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma
Authors: Zhang Xiao , Xu Yanfeng , Qian Zijun , Zheng Weisheng , Wu Qi , Chen Yan , Zhu Guoqing , Liu Ya , Bian Zhixuan , Xu Wen , Zhang Yue , Sun Fenyong , Pan Qiuhui , Wang Jiayi , Du Lutao , Yu Yongchun 
Published: October 2018

AbstractSome types of circular RNA (circRNA) are aberrantly expressed in human diseases including hepatocellular carcinoma (HCC). However, its regulation mechanism and diagnostic roles are largely unknown. Here, we identified that circRNA_104075 (circ_104075) was highly expressed in HCC tissues, cell lines and serum. Mechanistically, HNF4a bound to the −1409 to −1401 region of the circ_104075 promoter to stimulate the expression of circ_104075. Moreover, circ_104075 acted as a ceRNA to upregulate YAP expression by absorbing miR-582-3p. Interestingly, an N6-methyladenosine (m6A) motif was identified in the 353–357 region of YAP 3′UTR, and this m6A modification was essential for the interaction between miR-582-3p and YAP 3′UTR. Further, the diagnostic performance of circ_104075 was evaluated. The area under the receiver operating characteristic (AUC-ROC) for circ_104075 was 0.973 with a sensitivity of 96.0% and a specificity of 98.3%. Collectively, we determined that circ_104075 was highly expressed in HCC and elucidated its upstream and downstream regulatory mechanisms. circ_104075 additionally has the potential to serve as a new diagnostic biomarker in HCC. Targeting circ_104075 may provide new strategies in HCC diagnosis and therapy.
Interfacing nickel nitride and nickel boosts both electrocatalytic hydrogen evolution and oxidation reactions
Authors: Song Fuzhan , Li Wei , Yang Jiaqi , Han Guanqun , Liao Peilin , Sun Yujie 
Published: October 2018

AbstractElectrocatalysts of the hydrogen evolution and oxidation reactions (HER and HOR) are of critical importance for the realization of future hydrogen economy. In order to make electrocatalysts economically competitive for large-scale applications, increasing attention has been devoted to developing noble metal-free HER and HOR electrocatalysts especially for alkaline electrolytes due to the promise of emerging hydroxide exchange membrane fuel cells. Herein, we report that interface engineering of Ni3N and Ni results in a unique Ni3N/Ni electrocatalyst which exhibits exceptional HER/HOR activities in aqueous electrolytes. A systematic electrochemical study was carried out to investigate the superior hydrogen electrochemistry catalyzed by Ni3N/Ni, including nearly zero overpotential of catalytic onset, robust long-term durability, unity Faradaic efficiency, and excellent CO tolerance. Density functional theory computations were performed to aid the understanding of the electrochemical results and suggested that the real active sites are located at the interface between Ni3N and Ni.
Architecture of gene regulatory networks controlling flower development in Arabidopsis thaliana
Authors: Chen Dijun , Yan Wenhao , Fu Liang-Yu , Kaufmann Kerstin 
Published: October 2018

AbstractFloral homeotic transcription factors (TFs) act in a combinatorial manner to specify the organ identities in the flower. However, the architecture and the function of the gene regulatory network (GRN) controlling floral organ specification is still poorly understood. In particular, the interconnections of homeotic TFs, microRNAs (miRNAs) and other factors controlling organ initiation and growth have not been studied systematically so far. Here, using a combination of genome-wide TF binding, mRNA and miRNA expression data, we reconstruct the dynamic GRN controlling floral meristem development and organ differentiation. We identify prevalent feed-forward loops (FFLs) mediated by floral homeotic TFs and miRNAs that regulate common targets. Experimental validation of a coherent FFL shows that petal size is controlled by the SEPALLATA3-regulated miR319/TCP4 module. We further show that combinatorial DNA-binding of homeotic factors and selected other TFs is predictive of organ-specific patterns of gene expression. Our results provide a valuable resource for studying molecular regulatory processes underlying floral organ specification in plants.
Calcium sensing by the STIM1 ER-luminal domain
Authors: Gudlur Aparna , Zeraik Ana Eliza , Hirve Nupura , Rajanikanth V. , Bobkov Andrey A. , Ma Guolin , Zheng Sisi , Wang Youjun , Zhou Yubin , Komives Elizabeth A. , Hogan Patrick G. 
Published: October 2018

AbstractStromal interaction molecule 1 (STIM1) monitors ER-luminal Ca2+ levels to maintain cellular Ca2+ balance and to support Ca2+ signalling. The prevailing view has been that STIM1 senses reduced ER Ca2+ through dissociation of bound Ca2+ from a single EF-hand site, which triggers a dramatic loss of secondary structure and dimerization of the STIM1 luminal domain. Here we find that the STIM1 luminal domain has 5–6 Ca2+-binding sites, that binding at these sites is energetically coupled to binding at the EF-hand site, and that Ca2+ dissociation controls a switch to a second structured conformation of the luminal domain rather than protein unfolding. Importantly, the other luminal-domain Ca2+-binding sites interact with the EF-hand site to control physiological activation of STIM1 in cells. These findings fundamentally revise our understanding of physiological Ca2+ sensing by STIM1, and highlight molecular mechanisms that govern the Ca2+ threshold for activation and the steep Ca2+ concentration dependence.