bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of green product buying decision among young consumers in Malaysia
Authors: Tan Christine Nya Ling , Ojo Adedapo Oluwaseyi , Thurasamy Ramayah 
Published: June 2019

Purpose
This study aims to investigate the factors, which may potentially influence green product buying decision among young consumers in Malaysia.

Design/methodology/approach
A perceived lack of intention to buy green products observed among the Malaysian Generation Young consumers has sparked the interest to carry out this study. With the aid of structured questionnaires, data were collected from a total of 217 respondents, between 18 and 25 years of age.

Findings
The results of data analysis indicated that environmental consciousness, eco-label, price and advertising were significant predictors of green product buying behaviour. Contrary to the hypothesis, attitude was not a significant predictor of green buying behaviour among young consumers. The implications of these findings and directions for future research are outlined at the end of this paper.

Originality/value
This study offers empirical insights from the perspective of an emerging economy on the determinants of green products buying behaviour among young consumers.
Individual niche trajectories drive fitness variation
Authors: Costa‐Pereira Raul , Toscano Benjamin , Souza Franco L. , Ingram Travis , Araújo Márcio S. 
Published: June 2019

Abstract

Variation in fitness across individuals is central to population growth, species coexistence and evolution by natural selection. Fitness variation associated with resource use is hugely consequential, but how this variation is generated and maintained within natural populations remains unclear. In particular, individual fitness may depend on many cumulative foraging decisions over time, but this hypothesis remains untested.

We used multi‐tissue stable isotope analysis to determine isotopic niche trajectories within species, populations and sexes of thin‐toed frogs and explored how this temporal dimension of diet affects individual reproductive investment, body condition and parasite load.

We found that individual frogs shifted their diets less than expected under a null model, likely due to functional trade‐offs that limit the incorporation of new prey types over time. However, within the observed range of diet shifts, individuals that modified their diet to a greater degree exhibited higher fitness, although this effect was sex‐dependent.

We suggest that these different relationships between isotopic niche trajectory length and fitness within thin‐toed frogs are driven by variability in the resource environment, negative density dependence and allometric constraints. These strong fitness effects suggest that the temporal dimension of diet change is a potential target of natural selection and, therefore, could drive correlated evolution in phenotypic traits underlying diet flexibility. Our findings add a new level of complexity to the understanding of ecological and evolutionary consequences of niche variation by demonstrating that temporal variation in foraging consistency within populations leads to different fitness pay‐offs.

A free Plain Language Summary can be found within the Supporting Information of this article.
Cross‐seasonal legacy effects of arthropod community on plant fitness in perennial plants
Authors: Stam Jeltje M. , Kos Martine , Dicke Marcel , Poelman Erik H. 
Published: June 2019

Abstract

In perennial plants, interactions with other community members during the vegetative growth phase may influence community assembly during subsequent reproductive years and may influence plant fitness. It is well‐known that plant responses to herbivory affect community assembly within a growing season, but whether plant–herbivore interactions result in legacy effects on community assembly across seasons has received little attention. Moreover, whether plant–herbivore interactions during the vegetative growing season are important in predicting plant fitness directly or indirectly through legacy effects is poorly understood.

Here, we tested whether plant–arthropod interactions in the vegetative growing season of perennial wild cabbage plants, Brassica oleracea, result in legacy effects in arthropod community assembly in the subsequent reproductive season and whether legacy effects have plant fitness consequences. We monitored the arthropod community on plants that had been induced with either aphids, caterpillars or no herbivores in a full‐factorial design across 2 years. We quantified the plant traits ‘height’, ‘number of leaves’ and ‘number of flowers’ to understand mechanisms that may mediate legacy effects. We measured seed production in the second year to evaluate plant fitness consequences of legacy effects.

Although we did not find community responses to the herbivory treatments, our data show that community composition in the first year leaves a legacy on community composition in a second year: predator community composition co‐varied across years. Structural equation modelling analyses indicated that herbivore communities in the vegetative year correlated with plant performance traits that may have caused a legacy effect on especially predator community assembly in the subsequent reproductive year. Interestingly, the legacy of the herbivore community in the vegetative year predicted plant fitness better than the herbivore community that directly interacted with plants in the reproductive year.

Synthesis. Thus, legacy effects of plant–herbivore interactions affect community assembly on perennial plants across growth seasons and these processes may affect plant reproductive success. We argue that plant–herbivore interactions in the vegetative phase as well as in the cross‐seasonal legacy effects caused by plant responses to arthropod herbivory may be important in perennial plant trait evolution such as ontogenetic variation in growth and defence strategies.
Contrasting the Pb (II) and Cd (II) tolerance of Enterobacter sp. via its cellular stress responses
Authors: Jiang Zhongquan , Jiang Liu , Zhang Lin , Su Mu , Tian Da , Wang Tong , Sun Yalin , Nong Ying , Hu Shuijin , Wang Shimei , Li Zhen 
Published: June 2019

SummarySuccessful application of microorganisms to heavy metal remediation depends on their resistance to toxic metals. This study contrasted the differences of tolerant mechanisms between Pb2+ and Cd2+ in Enterobacter sp. Microbial respiration and production of formic acid showed that Enterobacter sp. had a higher tolerant concentration of Pb (>1000 mg l−1) than Cd (about 200 mg l−1). Additionally, SEM confirmed that most of Pb and Cd nanoparticles (NPs) were adsorbed onto cell membrane. The Cd stress, even at low concentration (50 mg l−1), significantly enlarged the sizes of cells. The cellular size raised from 0.4 × 1.0 to 0.9 × 1.6 μm on average, inducing a platelet‐like shape. In contrast, Pb cations did not stimulate such enlargement even up to 1000 mg l−1. Moreover, Cd NPs were adsorbed homogeneously by almost all the bacterial cells under TEM. However, only a few cells work as ‘hot spots’ on the sorption of Pb NPs. The heterogeneous sorption might result from a ‘self‐sacrifice’ mechanism, i.e., some cells at a special life stage contributed mostly to Pb sorption. This mechanism, together with the lower mobility of Pb cations, caused higher microbial tolerance and removal efficiency towards Pb2+. This study sheds evident contrasts of bacterial resistance to the two most common heavy metals.
Transcriptome responses to elevated CO2 level and Wolbachia‐infection stress in Hylyphantes graminicola (Araneae: Linyphiidae)
Authors: Su Qi‐Chen , Wang Xia , Deng Chan , Yun Yue‐Li , Zhao Yao , Peng Yu 
Published: June 2019

AbstractHylyphantes graminicola is a resident spider species found in maize and cotton fields and is an important biological control agent of various pests. Previous studies have demonstrated that stress from elevated CO2 and Wolbachia infection can strongly affect spider species. Thus, based on CO2 levels (400 ppm, current atmospheric CO2 concentration and 800 ppm, high CO2 concentration) and Wolbachia status (Wolbachia‐infected, W+ and Wolbachia‐uninfected, W−), we divided H. graminicola individuals into four treatment groups: W− 400 ppm, W− 800 ppm, W+ 400 ppm, and W+ 800 ppm. To investigate the effects of elevated CO2 levels (W− 400 vs W− 800), Wolbachia infection (W− 400 vs W+ 400), and the interactions between these two factors (W− 400 vs W+ 800), high‐throughput transcriptome sequencing was employed to characterize the de novo transcriptome of the spiders and identify stress‐related differentially expressed genes (DEGs). De novo assembly of complementary DNA sequences generated 86 688 unigenes, 23 938 of which were annotated in public databases. A total of 84, 21, and 157 DEGs were found among W− 400 vs W− 800, W− 400 vs W+ 400, and W− 400 vs W+ 800, respectively. Functional enrichment analysis revealed that metabolic processes, signaling, and catalytic activity were significantly affected by elevated CO2 levels and Wolbachia infection. Our findings suggest that the impact of elevated CO2 levels and Wolbachia infection on the H. graminicola transcriptome was, to a large extent, on genes involved in metabolic processes. This study is the first description of transcriptome changes in response to elevated CO2 levels and Wolbachia infection in spiders.
Associations between blood lead, cadmium, and mercury levels with hyperuricemia in the Korean general population: A retrospective analysis of population‐based nationally representative data
Authors: Jung Wonkil , Kim Yunkyung , Lihm Hoseob , Kang Jihun 
Published: June 2019

AbstractAimAn elevated serum uric acid level is associated with various diseases, such as gout, hypertension, renal impairment, and diabetes. Heavy metals, including lead and cadmium, are suspected to increase serum uric acid levels, but evidence regarding this is not sufficient, particularly in the Asian population. Therefore, this study aimed to evaluate the association between lead, cadmium and mercury exposure and hyperuricemia in the Korean general population.MethodsWe enrolled 2682 participants (1124 men and 1528 women) aged ≥19 years from The Korean National Health and Nutrition Examination Survey. Sex‐ and hyperuricemic state‐stratified general characteristics of study participants were compared using the Chi‐square test, Student's t test, and Mann–Whitney U test for categorical, continuous, and non‐normally distributed continuous variables, respectively. Multivariate logistic regression analysis was performed to evaluate the association between blood lead and cadmium levels and hyperuricemia.ResultsSubjects with hyperuricemia had higher blood lead and cadmium levels than those without hyperuricemia. Lead and cadmium exposure had a positive association with serum uric acid levels in a dose–response manner in the nationally representative Korean population. In logistic analysis, blood cadmium levels had a positive association with increasing risk for hyperuricemia only in men, and this association was more evident in cotinine‐verified non‐smokers. Although an incremental trend of hyperuricemia in relation to lead exposure was observed, it was not statistically significant.ConclusionFurther studies are necessary to clarify the observed association, and public health strategies to reduce heavy metal exposure may be necessary for decreasing the potential harmful effects of hyperuricemia.
Cannabidiol inhibits sucrose self‐administration by CB1 and CB2 receptor mechanisms in rodents
Authors: Bi Guo‐Hua , Galaj Ewa , He Yi , Xi Zheng‐Xiong 
Published: June 2019

AbstractA growing number of studies suggest therapeutic applications of cannabidiol (CBD), a recently U.S. Food and Drug Administration (FDA)–approved medication for epilepsy, in treatment of many other neuropsychological disorders. However, pharmacological action and the mechanisms by which CBD exerts its effects are not fully understood. Here, we examined the effects of CBD on oral sucrose self‐administration in rodents and explored the receptor mechanisms underlying CBD‐induced behavioral effects using pharmacological and transgenic approaches. Systemic administration of CBD (10, 20, and 40 mg/kg, ip) produced a dose‐dependent reduction in sucrose self‐administration in rats and in wild‐type (WT) and CB1−/− mice but not in CB2−/− mice. CBD appeared to be more efficacious in CB1−/− mice than in WT mice. Similarly, pretreatment with AM251, a CB1R antagonist, potentiated, while AM630, a selective CB2R antagonist, blocked CBD‐induced reduction in sucrose self‐administration, suggesting the involvement of CB1 and CB2 receptors. Furthermore, systemic administration of JWH133, a selective CB2R agonist, also produced a dose‐dependent reduction in sucrose self‐administration in WT and CB1−/− mice, but not in CB2−/− mice. Pretreatment with AM251 enhanced, while AM630 blocked JWH133‐induced reduction in sucrose self‐administration in WT mice, suggesting that CBD inhibits sucrose self‐administration likely by CB1 receptor antagonism and CB2 receptor agonism. Taken together, the present findings suggest that CBD may have therapeutic potential in reducing binge eating and the development of obesity.
Reduced bioavailability of oral amoxicillin tablets compared to suspensions in Roux‐en‐Y gastric bypass bariatric subjects
Authors: Montanha Maiara Camotti , dos Santos Magon Thiago Ferreira , de Souza Alcantara Conrado , Simões Caroline Ferraz , Silva Sandra Regina Bin , Kuroda Cristina Megumi , Yamada Sérgio Seiji , de Oliveira Lucas Eduardo Savóia , Nasser Daoud , Junior Nelson Nardo , Mazucheli Josmar , Diniz Andrea , Paixão Paulo Jorge Pereira Alves , Kimura Elza 
Published: June 2019

AimsTo evaluate the relative bioavailability of oral amoxicillin (AMX) tablets in comparison to AMX suspension in Roux‐en‐Y gastric bypass bariatric subjects.MethodsA randomized, double‐blind, cross‐over study was performed on the bioavailability of oral AMX tablets and suspension in Roux‐en‐Y gastric bypass subjects operated at least 3 months previously . Doses of 875 mg of the AMX tablet or 800 mg of the AMX suspension were given to all the subjects, allowing a washout of 7 days between the periods. Blood samples were collected at 0, 0.25, 0.5, 1, 1.5, 2, 4, 6 and 8 hours after drug administration and the AMX levels were quantified by liquid chromatography coupled with triple quadrupole tandem mass spectrometry. The pharmacokinetic parameters were calculated by noncompartmental analysis, normalized to an 875 mg dose and the bioavailability of the AMX from the tablets was compared to that from the suspension formulation.ResultsTwenty subjects aged 42.65 ± 7.21 years and with a body mass index of 29.88 ± 4.36 kg/m2 were enrolled in the study. The maximum AMX plasma concentration of the tablets and the suspension (normalized to 875 mg) were 7.42 ± 2.99 mg/L and 8.73 ± 3.26 mg/L (90% confidence interval of 70.71–99.11), and the total area under the curve from time zero to infinity were 23.10 ± 7.41 mg.h/L and 27.59 ± 8.32 mg.h/L (90% confidence interval of 71.25–97.32), respectively.ConclusionThe tablets presented a lower bioavailability than the suspension formulation and the total absorbed amount of AMX in these subjects was lower in comparison to the standard AMX absorption rates in nonbariatric subjects, regardless of the formulation.
The duration of the third stage in relation to postpartum hemorrhage
Authors: van Ast Manon , Goedhart Martijn M. , Luttmer Roosmarijn , Orelio Claudia , Deurloo Koen L. , Veerbeek Jan 
Published: June 2019

AbstractIntroductionIn this study, we describe the distribution of placenta delivery and the incidence of postpartum hemorrhage in both spontaneous placental delivery and manual removal of the placenta.MethodsA retrospective study was performed of 7603 singleton vaginal deliveries of a gestational age over 32 weeks, registered between September 2011 and 2016. We calculated the incidence of postpartum hemorrhage (≥1000 mL blood loss) per 10‐minute duration of the third stage. The odds ratio for developing postpartum hemorrhage was assessed, adjusted for risk factors. The incidence of postpartum hemorrhage was compared between women that did and did not receive manual removal of placenta.ResultsThe median duration of the third stage was 10 minutes (interquartile range 7‐16 minutes). The median amount of blood loss was 300 mL (200‐400 mL). The overall incidence of postpartum hemorrhage was 8.5%. With every additional 10 minutes of third‐stage duration, the risk of developing postpartum hemorrhage significantly increased. In a third stage longer than 60 minutes, the incidence of postpartum hemorrhage was 21.2% without manual removal of the placenta and 70.3% with manual removal.ConclusionsThe incidence of postpartum hemorrhage increases significantly from 10 to 19 minutes into the third stage. Women with the removal of the placenta had a significantly higher percentage of postpartum hemorrhage. The optimal timing for manual removal of the placenta should be investigated in a carefully designed randomized controlled trial to examine whether earlier manual removal of placenta lowers the incidence and limits the severity of postpartum hemorrhage.
Knowledge structures for integrating working and learning: A reflection on a decade of learning technology research for workplace learning
Authors: Ley Tobias 
Published: June 2019

AbstractDesigning intelligent services for workplace learning presents a special challenge for researchers and developers of learning technology. One of the reasons is that considering learning as a situated and social practice is nowhere so important than in the case where learning is tightly integrated with workplace practices. The current paper analyses the experience of more than 10 years of research intending to offer intelligent services through capturing and leveraging knowledge structures in workplace learning. The reflection looks at results of several European research projects that have promoted this view. From this analysis, I arrive at a dichotomy of guidance versus emergence that describes how the technologies foregrounded one or the other, and what the effects of these design choices have been. I derive conclusions for dealing with this design trade‐off in terms of conceptual, technological and empirical research.
A way forward with eco evo devo: an extended theory of resource polymorphism with postglacial fishes as model systems
Authors: Skúlason Skúli , Parsons Kevin J. , Svanbäck Richard , Räsänen Katja , Ferguson Moira M. , Adams Colin E. , Amundsen Per‐Arne , Bartels Pia , Bean Colin W. , Boughman Janette W. , Englund Göran , Guðbrandsson Jóhannes , Hooker Oliver E. , Hudson Alan G. , Kahilainen Kimmo K. , Knudsen Rune , Kristjánsson Bjarni K. , Leblanc Camille A‐L. , Jónsson Zophonías , Öhlund Gunnar , Smith Carl , Snorrason Sigurður S. 
Published: June 2019

ABSTRACTA major goal of evolutionary science is to understand how biological diversity is generated and altered. Despite considerable advances, we still have limited insight into how phenotypic variation arises and is sorted by natural selection. Here we argue that an integrated view, which merges ecology, evolution and developmental biology (eco evo devo) on an equal footing, is needed to understand the multifaceted role of the environment in simultaneously determining the development of the phenotype and the nature of the selective environment, and how organisms in turn affect the environment through eco evo and eco devo feedbacks. To illustrate the usefulness of an integrated eco evo devo perspective, we connect it with the theory of resource polymorphism (i.e. the phenotypic and genetic diversification that occurs in response to variation in available resources). In so doing, we highlight fishes from recently glaciated freshwater systems as exceptionally well‐suited model systems for testing predictions of an eco evo devo framework in studies of diversification. Studies on these fishes show that intraspecific diversity can evolve rapidly, and that this process is jointly facilitated by (i) the availability of diverse environments promoting divergent natural selection; (ii) dynamic developmental processes sensitive to environmental and genetic signals; and (iii) eco evo and eco devo feedbacks influencing the selective and developmental environments of the phenotype. We highlight empirical examples and present a conceptual model for the generation of resource polymorphism – emphasizing eco evo devo, and identify current gaps in knowledge.
Vasorin stimulates malignant progression and angiogenesis in glioma
Authors: Liang Weiye , Guo Baoyin , Ye Jiecheng , Liu Hui , Deng Wanying , Lin Chenli , Zhong Xueyun , Wang Lihui 
Published: June 2019

AbstractGlioma, the most common human primary brain tumor, is characterized by invasive capabilities and angiogenesis. Vasorin (VASN), a transmembrane protein, is reported to be associated with vascular injury repair and is overexpressed in some human tumors. However, its role in tumor progression and angiogenesis in glioma is unknown. In this study, VASN was shown to be overexpressed in high‐grade gliomas, and the expression level correlated with tumor grade and microvessel density in glioma specimens. Glioma patients with high VASN expression had a shorter overall survival time. Knockdown of VASN in glioma cells by shRNA significantly inhibited the malignancy of glioma, including cell proliferation, colony formation, invasion, and sphere formation. Ectopic expression of VASN increased glioma progression in vitro. The expression of VASN correlated with the mesenchymal type of glioblastoma multiforme (GBM) subtyped by gene set enrichment analysis (GSEA). Our results showed that the concentration of VASN was increased in the conditioned medium (CM) from glioma cells with VASN overexpression, and the CM from glioma cells with knockdown or overexpressed VASN inhibited or promoted HUVEC migration and tubulogenesis in vitro, respectively. Glioma growth and angiogenesis were stimulated upon ectopic expression of VASN in vivo. The STAT3 and NOTCH pathways were found to be activated and inhibited by VASN overexpression. Our findings suggest that VASN stimulates tumor progression and angiogenesis in glioma, and, as such, represents a novel therapeutic target for glioma.
Colour recipe prediction using ant colony algorithm: principle of resolution and analysis of performances
Authors: Chaouch Sabrine , Moussa Ali , Ben Marzoug Imed , Ladhari Neji 
Published: June 2019

AbstractThis paper presents a new method for colour recipe prediction using ant colony optimisation. Three reactive dyes, namely CI Reactive Yellow 145, CI Reactive Red 238 and CI Reactive Blue 235, were used for colour formulation. Samples of 100% cotton fabrics were used for dyeing. The objective was to assure, control and optimise the colour formulation step by determining the dyes to be applied and their respective concentrations to reproduce the desired shades. The criterion of optimisation is to minimise the colour differences [Colour Measurement Committee (2:1)] between the target colour and the colour obtained by the proposed recipe. Errors between the proposed recipe and actual concentrations are also evaluated. The developed algorithm showed good performances with small colour differences between the target and reproduced colours (all lower than 0.7).