bluuebunny/crossref_metadata_2025_split huggingface dataset:
История развития и современное состояние процесса каталитического риформинга в России . Опыт промышленного производства и эксплуатации новых катализаторов риформинга серии ПР
Authors: Kir'yanov D. , Smolikov M. , Golinsky D. , Belopukhov E. , Zatolokina E. , Udras I. , Belyi A. 
Published: February 2019

В работе представлена история развития и современное состояние процесса каталитического риформинга в России. Дана информация по ассортименту действующих установок риформинга, их основные проектные характеристики, а также перечень применяемых отечественных и зарубежных катализаторов процесса. Представлен промышленный опыт производства и эксплуатации нового катализатора риформинга ПР-81 за последние 8 лет. Достигнутые результаты могут быть полезны для более широкого внедрения нового катализатора на НПЗ России и других стран.
Газофазное и жидкофазное гидрирование ацетилена в обедненных и обогащенных смесях на нанесенных модифицированных палладиевых катализаторах
Authors: Glyzdova DV . , Smirnova N.S . , Shlyapin D.A . , Tsyrul’nikov P.G. 
Published: February 2019

В представленном обзоре обобщены результаты исследований, посвященных селективному гидрированию ацетилена в этилен на биметаллических палладиевых катализаторах. Проанализированы общие закономерности и особенности их действия в газофазном гидрировании следов ацетилена в ацетилен-этиленовой смеси, получаемой пиролизом нефтяного сырья, а также в процессе жидкофазного гидрирования смесей, обогащенных ацетиленом и водородом. Показаны преимущества получения этилена путем гидрирования ацетилена в жидкой фазе и рассмотрены способы повышения селективности этого процесса.
ГИДРОИЗОМЕРИЗАЦИЯ БЕНЗОЛСОДЕРЖАЩИХ БЕНЗИНОВЫХ ФРАКЦИЙ – ОСНОВА СОВРЕМЕННЫХ ТЕХНОЛОГИЙ ПОЛУЧЕНИЯ ЭКОЛОГИЧЕСКИ ЧИСТЫХ МОТОРНЫХ ТОПЛИВ
Authors: Fedorova E.D. , Lavrenov A.V. , Buluchevskiy E.A. , Bogdanets E.N. 
Published: February 2019

В обзоре представлен анализ научно-технической и патентной информации о гидроизомеризации бензолсодержащих бензиновых фракций, как способе получения компонентов экологически чистых высокооктановых компонентов моторных топлив. Рассмотрены преимущества и недостатки основных способов каталитической переработки бензолсодержащих фракций – гидрирования бензола, алкилирования бензола олефинами. Особое внимание уделено перспективным катализаторам и технологиям гидроизомеризации бензолсодержащих фракций.
Scheduling Flexible Manufacturing System with Stacker Crane Using Coloured Petri Nets
Authors: Setiawan Ari , Sitepu Teguh Ersada Natail 
Published: February 2019

Scheduling Flexible Manufacturing System (FMS) can increase production speed and accuracy. It because FMS has an ability to process various variety of product at same work station. However, FMS need efficient allocation of resources, for example: allocation of material handling equipment. This paper presents production scheduling FMS modelling to 24 jobs and 4 machines considering stacker crane. Coloured Petri Nets (CP-Nets) is the programming language which used to simulate model because it’s simplicity. This model consists two main model activities. The first one is Physical Activity (PA) which related to every activity that involve physical movement, including stacker crane processes. PA consist five CP-Nets models: loading/unloading station, stacker crane, machine, picking mechanism, and pallet stocker. The second activity is Logical Expression (LE) which related to the rules on how FMS should operate. LE consist three CP-Nets models: machine selection, pick-up request, and stage two procedure. A simulation and numerical report show utilization level of all machines around 80-84% and stacker crane 8,74%.
Exploiting DNA repair defects in colorectal cancer
Authors: Reilly Nicole M. , Novara Luca , Di Nicolantonio Federica , Bardelli Alberto 
Published: February 2019

Colorectal cancer (CRC) is the third leading cause of cancer‐related deaths worldwide. Therapies that take advantage of defects in DNA repair pathways have been explored in the context of breast, ovarian, and other tumor types, but not yet systematically in CRC. At present, only immune checkpoint blockade therapies have been FDA approved for use in mismatch repair‐deficient colorectal tumors. Here, we discuss how systematic identification of alterations in DNA repair genes could provide new therapeutic opportunities for CRCs. Analysis of The Cancer Genome Atlas Colon Adenocarcinoma (TCGA‐COAD) and Rectal Adenocarcinoma (TCGA‐READ) PanCancer Atlas datasets identified 141 (out of 528) cases with putative driver mutations in 29 genes associated with DNA damage response and repair, including the mismatch repair and homologous recombination pathways. Genetic defects in these pathways might confer repair‐deficient characteristics, such as genomic instability in the absence of homologous recombination, which can be exploited. For example, inhibitors of poly(ADP)‐ribose polymerase are effectively used to treat cancers that carry mutations in BRCA1 and/or BRCA2 and have shown promising results in CRC preclinical studies. HR deficiency can also occur in cells with no detectable BRCA1/BRCA2 mutations but exhibiting BRCA‐like phenotypes. DNA repair‐targeting therapies, such as ATR and CHK1 inhibitors (which are most effective against cancers carrying ATM mutations), can be used in combination with current genotoxic chemotherapies in CRCs to further improve therapy response. Finally, therapies that target alternative DNA repair mechanisms, such as thiopurines, also have the potential to confer increased sensitivity to current chemotherapy regimens, thus expanding the spectrum of therapy options and potentially improving clinical outcomes for CRC patients.
No evidence that alcohol intoxication impairs judgments of learning in face recognition
Authors: Monds Lauren A. , Kloft Lilian , Sauer James D. , Honan Cynthia A. , Palmer Matthew A. 
Published: February 2019

SummaryAlcohol use is frequently involved in crime, making it crucial to understand the role of alcohol in facial recognition to maximize correct perpetrator identifications. Although the majority of the alcohol and face recognition research has investigated recognition with retrospective confidence judgments, we examined the effects of alcohol intoxication on face recognition with prospective metacognitive judgments. Participants (N = 54 university students without a history of hazardous alcohol/substance use) consumed either alcohol (mean breath alcohol concentration of 0.06 at pretest and 0.07 at post‐test) or a non‐alcoholic placebo drink. Participants then studied unfamiliar male and female faces and made judgments of learning (JOLs) for each face (i.e., predicted the likelihood of recognizing that face on a future memory test). After a brief distractor task, participants completed an old–new recognition test on which they attempted to distinguish the studied faces from new faces. It was found that the alcohol manipulation had minimal effect on face recognition performance or judgments of learning. Our results suggest that theory‐based cues about the effects of alcohol might play a greater role in retrospective judgments than prospective judgments. Although not a primary focus of the study, face recognition was better for male faces than female faces, and this occurred for both female and male participants. Limitations and implications of the research are discussed.
Hierarchical Spiky Microstraws‐Integrated Microfluidic Device for Efficient Capture and In Situ Manipulation of Cancer Cells
Authors: He Gen , Yang Chengduan , Feng Jianming , Wu Jiangming , Zhou Lingfei , Wen Rui , Huang Shuang , Wu Qianni , Liu Fanmao , Chen Hui‐Jiuan , Hang Tian , Xie Xi 
Published: February 2019

AbstractTechniques for capturing circulating tumor cells (CTCs) play an important role in cancer diagnosis. Recently, various 3D micro/nanostructures have been applied for effective CTC detection, yet in situ manipulation of the captured cancer cells on micro/nano‐structural substrates is rarely achieved. In this work, a hierarchical spiky microstraw array (HS‐MSA)‐integrated microfluidic device is demonstrated that possessed dual functions of cancer cell capture and in situ chemical manipulations of the captured cells. The 3D micro/nanostructure of HS‐MSA could capture cancer cells with high efficiency (≈84%) and strong specificity. Based on the HS‐MSA‐integrated microfluidic device, extracellular drug delivery to the captured cancer cells is achieved in situ with excellent spatial, dose, and temporal controls. In addition, a drug‐screening assay on the captured cancer cells is implemented to investigate the cell apoptosis behavior under the microstraw‐mediated delivery of staurosporine (STS). This microfluidic system not only presents tremendous potential for CTCs detection technology, but also opens up new opportunities for high‐throughput drug screening on cancer cells and understanding the cellular activity.
Photon‐Induced Reversible Phase Transition in CsPbBr3 Perovskite
Authors: Xue Jie , Yang Dandan , Cai Bo , Xu Xiaobao , Wang Jian , Ma He , Yu Xuechao , Yuan Guoliang , Zou Yousheng , Song Jizhong , Zeng Haibo 
Published: February 2019

AbstractStructure reorganization within perovskite materials has attracted much attention due to its assisted appealing features in optoelectronic devices, such as achieving continue‐wave laser and performance enhancement in photovoltaic devices. Unfortunately, the difficulty of controlling reorganization processing and unclear underlying mechanisms impose an impediment for taking advantage of the structural reorganization in pursuit of distinctive functions in perovskite‐based devices. In this work, using above‐bandgap illumination with a small energy threshold (1.6 mW cm−2) triggering phase transition from orthorhombic to tetragonal in CsPbBr3 is first reported. This photon‐induced structure reorganization is reversible and presents a fast and controllable response (<0.5 s) to light on/off. Raman spectroscopy and density functional theory calculations reveal that such a dynamic structure reorganization is caused by the transition of torsion direction in Pb–Br octahedral, while the diffusion potential difference induced local Coulombic field is proved to drive this process. The findings provide a deep understanding for universal structure reorganization under irradiation in perovskite materials and encourage further study of the novel functions associated with structure reorganization inducing temporal behaviors in optoelectronic devices, for example variations in dielectric constant and band edge fluctuation induced Rashba effects, which show a significant influence on perovskite‐based optoelectronic devices.
A Biocompatible Therapeutic Catheter‐Deliverable Hydrogel for In Situ Tissue Engineering
Authors: Steele Amanda N. , Stapleton Lyndsay M. , Farry Justin M. , Lucian Haley J. , Paulsen Michael J. , Eskandari Anahita , Hironaka Camille E. , Thakore Akshara D. , Wang Hanjay , Yu Anthony C. , Chan Doreen , Appel Eric A. , Woo Yiping Joseph 
Published: February 2019

AbstractHydrogels have emerged as a diverse class of biomaterials offering a broad range of biomedical applications. Specifically, injectable hydrogels are advantageous for minimally invasive delivery of various therapeutics and have great potential to treat a number of diseases. However, most current injectable hydrogels are limited by difficult and time‐consuming fabrication techniques and are unable to be delivered through long, narrow catheters, preventing extensive clinical translation. Here, the development of an easily‐scaled, catheter‐injectable hydrogel utilizing a polymer–nanoparticle crosslinking mechanism is reported, which exhibits notable shear‐thinning and self‐healing behavior. Gelation of the hydrogel occurs immediately upon mixing the biochemically modified hyaluronic acid polymer with biodegradable nanoparticles and can be easily injected through a high‐gauge syringe due to the dynamic nature of the strong, yet reversible crosslinks. Furthermore, the ability to deliver this novel hydrogel through a long, narrow, physiologically‐relevant catheter affixed with a 28‐G needle is highlighted, with hydrogel mechanics unchanged after delivery. Due to the composition of the gel, it is demonstrated that therapeutics can be differentially released with distinct elution profiles, allowing precise control over drug delivery. Finally, the cell‐signaling and biocompatibility properties of this innovative hydrogel are demonstrated, revealing its wide range of therapeutic applications.
An In Situ Procedure for the Preparation of Zeolitic Imidazolate Framework‐8 Polyacrylamide Hydrogel for Adsorption of Aqueous Pollutants
Authors: Maan Omar , Song Ping , Chen Ningxin , Lu Qingye 
Published: February 2019

AbstractMetal–organic frameworks (MOFs) have attracted a lot of attention in recent years because of their high surface area and tunable porosities, which allow them to serve as excellent and versatile adsorbents for pollutants in water/wastewater. One of the demanding challenges of using MOFs is that they need to be supported on a substrate or in a matrix to be easier to operate and more efficiently used. This work presents a simple in situ method of synthesizing one of the most popular MOF particles, zeolitic imidazolate framework 8 (ZIF‐8), in a polyacrylamide (PAM) hydrogel using a zinc hydroxide PAM composite as a precursor gel. Characterization of the prepared ZIF‐8 PAM composite hydrogel by scanning electron microscope, energy‐dispersive X‐ray spectroscopy, X‐ray powder diffraction, Fourier‐transform infrared spectroscopy, and X‐ray photoelectron spectroscopy confirms the successful synthesis of ZIF‐8 particles on the surface of and inside the PAM hydrogel. To test the potential of this novel material as an adsorbent, its ability to remove humic acid (HA), a model organic pollutant, from water is evaluated. The maximum adsorption capacity for HA is found to be 111.5 ± 3.0 mg g−1 ZIF‐8, comparable to the performance of other adsorbents for the removal of HA.
Single‐Electron‐Transfer‐Initiated Sequential Direct Arylation Reaction of Pyrrole with Aryl Diazonium Salts
Authors: Yamaguchi Eiji , Kashima Yayoi , Itoh Akichika 
Published: February 2019

AbstractDirect and sequential arylations of pyrrole with a diazonium salt were initiated by single electron transfer from cobaltocene. The direct arylation reaction of pyrrole was completed within 30 min even at room temperature and the corresponding arylated product was obtained in good yield. The second arylation reaction of monoarylated heteroarenes also proceeded successfully and moderate to good yields of diarylated pyrroles were obtained. A gram‐scale reaction also proceeded without decreasing the yield of the product.
Palladium‐Catalyzed Trifluoroethylation of Benzo[h]quinoline Derivatives by Mesityl(2,2,2‐trifluoroethyl)iodonium Triflate
Authors: Han Qiu‐Yan , Hu Xiaoxiao , Xue Xiao‐Song , Zhao Cheng‐Long , Zhang Cheng‐Pan 
Published: February 2019

AbstractReactions of a dimeric [(bzq)Pd(OAc)]2 complex (1 a′) and mesityl(2,2,2‐trifluoroethyl)iodonium triflate (2 a) with or without additives at room temperature gave 10‐(2,2,2‐trifluoroethyl)benzo[h]quinoline rapidly in moderate to high yields. The reaction might proceed through a unstable binuclear “PdIII−CH2CF3” intermediate (I), which was likely formed in situ from the oxidative addition of 2 a to [(bzq)Pd(OAc)]2 and favorably transformed to mononuclear “(bzq)PdIV−CH2CF3” complexes (III) in the presence of another equiv.alent of 2 a and a suitable additive. Based on these, a Pd‐catalyzed C−H trifluoroethylation of benzo[h]quinolines with 2 a was developed. Numerous benzo[h]quinoline derivatives reacted with [MesICH2CF3][OTf] at room temperature in the presence of 10 mol% Pd(OAc)2 and 2 equiv.. NaHCO3 to provide the corresponding 10‐trifluoroethylated products in excellent yields.
Use of intranasal submucosal fillers as a transient implant to alter upper airway aerodynamics: implications for the assessment of empty nose syndrome
Authors: Borchard Nicole A. , Dholakia Sachi S. , Yan Carol H. , Zarabanda David , Thamboo Andrew , Nayak Jayakar V. 
Published: February 2019

BackgroundEmpty nose syndrome (ENS) is a debilitating condition associated with inferior turbinate tissue loss. Surgical augmentation of the inferior meatus has been proposed to treat ENS, although efficacy data with validated, disease‐specific questionnaires is limited. Instead we evaluated submucosal injection of a transient, resorbable filler into the inferior meatus to favorably alter nasal aerodynamics in ENS patients.MethodsPatients with a history of inferior turbinate reduction, diagnosed with ENS via Empty Nose Syndrome 6‐Item Questionnaire (ENS6Q) and cotton testing, were enrolled and underwent submucosal injection of carboxymethylcellulose/glycerin gel (Prolaryn®) into the inferior meatuses between July 2014 and May 2018. This material likely resorbs over several months. Outcomes included comparisons of preinjection and postinjection symptoms at 1 week, 1 month, and 3 months using the ENS6Q, 22‐item Sino‐Nasal Outcome Test (SNOT‐22), Generalized Anxiety Disorder 7‐item scale (GAD‐7), and Patient Health Questionnaire‐9 (PHQ‐9).ResultsFourteen patients underwent injections. Mean ENS6Q scores significantly decreased from baseline at 1 week (20.8 vs 10.5; p < 0.0001), and remained reduced but upward‐trending at 1 month (13.7, p = 0.002) and 3 months (15.5, p > 0.05) following injections. Mean SNOT‐22 scores significantly decreased at 1 week (p = 0.01) and 1 month (p = 0.04), mean GAD‐7 at 1 month (p = 0.02) and 3 months (p = 0.02), and mean PHQ‐9 at 1 week (p = 0.01) and 1 month (p = 0.004) postinjection.ConclusionTransient, focal airway bulking via submucosal filler injection at sites of inferior turbinate tissue loss markedly benefits ENS patients, suggesting that aberrant nasal aerodynamics from inferior turbinate tissue loss contributes to (potentially reversible) ENS symptoms.
Composite‐Assisted Phase‐Matching: Efficient Wavelength Conversion in Nonlinear Optical Composite Materials Containing Metal Nanoparticles
Authors: Kim Kwang‐Hyon , Rim Wi‐Song 
Published: February 2019

AbstractA novel phase‐matching scheme which is based on the dispersion compensation in the nonlinear optical composite materials containing metal nanoparticles is proposed. Anomalous dispersion originating from the plasmon resonance in metal nanoparticles compensates the dispersion of the host nonlinear material, leading to the perfect phase‐matching and high efficiency of nonlinear optical wavelength conversion. The effectiveness of this approach is theoretically demonstrated, taking third‐order nonlinear processes such as the direct third‐harmonic generation and four‐wave mixing in ZnO composites containing silica‐core–silver‐shell nanoparticles as examples. The results show that with the proposed phase‐matching scheme, unprecedentedly high conversion efficiency can be obtained compared with preceding results in third‐order nonlinear optical solid‐state materials.
Sustainable Co‐Synthesis of Glycolic Acid, Formamides and Formates from 1,3‐Dihydroxyacetone by a Cu/Al2O3 Catalyst with a Single Active Sites
Authors: Dai Xingchao , Adomeit Sven , Rabeah Jabor , Kreyenschulte Carsten , Brückner Angelika , Wang Hongli , Shi Feng 
Published: February 2019

AbstractGlycolic acid (GA), as important building block of biodegradable polymers, has been synthesized for the first time in excellent yields at room temperature by selective oxidation of 1,3‐dihyroxyacetone (DHA) using a cheap supported Cu/Al2O3 catalyst with single active CuII species. By combining EPR spin‐trapping and operando ATR‐IR experiments, different mechanisms for the co‐synthesis of GA, formates, and formamides have been derived, in which .OH radicals formed from H2O2 by a Fenton‐like reaction play a key role.
ZnSe Nanorods as Visible‐Light Absorbers for Photocatalytic and Photoelectrochemical H2 Evolution in Water
Authors: Kuehnel Moritz F. , Creissen Charles E. , Sahm Constantin D. , Wielend Dominik , Schlosser Anja , Orchard Katherine L. , Reisner Erwin 
Published: February 2019

AbstractA precious‐metal‐ and Cd‐free photocatalyst system for efficient H2 evolution from aqueous protons with a performance comparable to Cd‐based quantum dots is presented. Rod‐shaped ZnSe nanocrystals (nanorods, NRs) with a Ni(BF4)2 co‐catalyst suspended in aqueous ascorbic acid evolve H2 with an activity up to 54±2 mmol
gZnSe−1 h−1 and a quantum yield of 50±4 % (λ=400 nm) under visible light illumination (AM 1.5G, 100 mW cm−2, λ>400 nm). Under simulated full‐spectrum solar irradiation (AM 1.5G, 100 mW cm−2), up to 149±22 mmol
gZnSe−1 h−1 is generated. Significant photocorrosion was not noticeable within 40 h and activity was even observed without an added co‐catalyst. The ZnSe NRs can also be used to construct an inexpensive delafossite CuCrO2 photocathode, which does not rely on a sacrificial electron donor. Immobilized ZnSe NRs on CuCrO2 generate photocurrents of around −10 μA cm−2 in an aqueous electrolyte solution (pH 5.5) with a photocurrent onset potential of approximately +0.75 V vs. RHE. This work establishes ZnSe as a state‐of‐the‐art light absorber for photocatalytic and photoelectrochemical H2 generation.
Superhydrophilic Phytic‐Acid‐Doped Conductive Hydrogels as Metal‐Free and Binder‐Free Electrocatalysts for Efficient Water Oxidation
Authors: Hu Qi , Li Guomin , Liu Xiufang , Zhu Bin , Chai Xiaoyan , Zhang Qianling , Liu Jianhong , He Chuanxin 
Published: February 2019

AbstractRecently, metal‐free, heteroatom‐doped carbon nanomaterials have emerged as promising electrocatalysts for the oxygen evolution reaction (OER), but their synthesis is a tedious process involving energy‐wasting calcination. Molecular electrocatalysts offer attractive catalysts for the OER. Here, phytic acid (PA) was selected to investigate the OER activity of carbons in organic molecules by DFT calculations and experiments. Positively charged carbons on PA were very active towards the OER. The PA molecules were fixed into a porous, conductive hydrogel with a superhydrophilic surface. This outperformed most metal‐free electrocatalysts. Besides the active sites on PA, the high OER activity was also related to the porous and conductive networks on the hydrogel, which allowed fast charge and mass transport during the OER. Therefore, this work provides a metal‐free, organic‐molecule‐based electrocatalyst to replace carbon nanomaterials for efficient OER.
Bimetallic Catalytic Asymmetric Tandem Reaction of β‐Alkynyl Ketones to Synthesize 6,6‐Spiroketals
Authors: Ge Shulin , Cao Weidi , Kang Tengfei , Hu Bowen , Zhang Hang , Su Zhishan , Liu Xiaohua , Feng Xiaoming 
Published: February 2019

AbstractThe enantioselective tandem reaction of β,γ‐unsaturated α‐ketoesters with β‐alkynyl ketones was realized by a bimetallic catalytic system of achiral AuΙΙΙ salt and chiral N,N′‐dioxide‐MgΙΙ complex. The cycloisomerization of β‐alkynyl ketone and asymmetric intermolecular [4+2] cycloaddition with β,γ‐unsaturated α‐ketoesters subsequently occurred, providing an efficient and straightforward access to chiral multifunctional 6,6‐spiroketals in up to 97 % yield, 94 % ee and >19/1 d.r. Besides, a catalytic cycle was proposed based on the results of control experiments.
Zeolite‐Type Metal Oxalate Frameworks
Authors: Yi Fei‐Yan , Yang Huajun , Zhao Xiang , Feng Pingyun , Bu Xianhui 
Published: February 2019

AbstractWhile many metal oxalate salts are known, few are known to form zeolite‐type topologies. The construction of zeolite types, especially those with low framework density such as RHO, from linear ligands is generally perceived as less likely, because the 180° metal‐ligand‐metal geometry deviates too much from the established strategy of using ligands with bent coordination geometry (centered around 145°) to mimic the geometry in natural zeolites. We show the general feasibility of using linear ligands for the synthesis of zeolite types by reporting a family of indium oxalate salts with multiple zeolite topologies, including RHO, GIS, and ABW. Of particular interest is the synthesis of a zeolite RHO net with double 8‐rings and large alpha cages, which are highly desirable zeolite features.