bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparison of the anatomical and gastrointestinal functional development between gilt and sow progeny around birth and weaning1
Authors: Craig Jessica R , Dunshea Frank R , Cottrell Jeremy J , Furness John B , Wijesiriwardana Udani A , Pluske John R 
Published: July 2019

AbstractGilt progeny (GP) often have restricted growth performance and health status in comparison to sow progeny (SP) from birth, with the underlying mechanisms responsible for this yet to be fully understood. The present study aimed to compare differences in growth and development between GP and SP in the first 24 h after birth and in the periweaning period. Two cohorts of pigs including 36 GP and 37 SP were euthanized at 1 of 4 time points: a birth cohort (at birth before suckling, 0 h; and 24 h after birth, 24 h; n = 33) and a weaning cohort (at approximately 29 d of age; “pre-weaning,” PrW; and 24 h after weaning; “post-weaning,” PoW; n = 40). Pigs were individually weighed at 0 h, 24 h, PrW, and PoW up until the point of euthanasia, at which time the weights of selected tissues and organs were recorded and analyzed relative to BW. The length of the small intestine (SI), femur, and body were also measured, and a serum sample was collected and analyzed for IgG concentration. Samples of jejunal and ileal mucosa were collected and analyzed for total protein and specific activity of lactase. Euthanized GP were lighter (P < 0.01) than SP at all time points. At all time points, the ratios of quadriceps weight to femur length, BW to body length, spleen to BW (all P < 0.05), and SI weight to length (P < 0.10) were lower in GP than in SP. There was no difference (P ≥ 0.05) in stomach or heart to BW ratios between GP and SP in either cohort. The brain to liver weight ratio was greater (P = 0.044) in GP than in SP in the birth cohort, and the brain to BW ratio was greater (P < 0.01) in GP in both the birth and weaning cohorts. The liver to BW ratio was similar (P = 0.35) at birth but greater (P = 0.014) in GP around weaning. Total mucosal protein content in the jejunum and ileum was lower (P = 0.007) in GP at 24 h compared with SP, and specific activity of lactase was greater (P = 0.022) in GP in the birth cohort, whereas there were no differences in the weaning cohort (P ≥ 0.10). Gilt progeny had lower (P < 0.001) serum IgG concentration compared with SP at 24 h, but there was no difference (P ≥ 0.10) in the weaning cohort. Collectively, these findings suggest that the early development of GP may be delayed compared with SP and that a number of the anatomical differences between GP and SP that exist after birth are also present at weaning.
Dynamic agglomeration economies and learning by working in specialised regions
Authors: Peters Jan Cornelius 
Published: July 2019

Abstract
This study provides new evidence on the magnitude of dynamic agglomeration economies. It estimates the elasticity of entry wage with regard to the size of the regional labour markets in which previous work experience was acquired and considers, furthermore, the workforce compositions in these regions. The results indicate that not only the sheer size of regional labour markets determine individual knowledge accumulation. Benefits from acquiring experience in large labour markets by workers in service sector occupations are partly caused by human capital externalities, whereas manufacturing workers experience additional dynamic gains from localisation economies, in Germany particularly outside urban centres.
Mutant p53—a potential player in shaping the tumor–stroma crosstalk
Authors: Stein Yan , Aloni-Grinstein Ronit , Rotter Varda 
Published: July 2019

Abstract
A plethora of studies suggest that the non-transformed cellular and non-cellular components of the tumor, collectively known as the tumor microenvironment, have a significant impact on the tumorigenic process. It was suggested that the microenvironment, which initially restricts tumor development, is recruited by the tumor and maintains a crosstalk that further promotes cancer progression. Indeed, many of the molecules that participate in the tumor–stroma crosstalk have been characterized. However, the crucial factors that are responsible for the initiation of this crosstalk or the ‘recruitment’ process remain poorly understood. We propose that oncogenes themselves may influence the ‘recruitment’ of the stromal cells, while focusing on mutant p53. Apart from losing its tumor-suppressing properties, mutant p53 gains novel oncogenic functions, a phenomenon dubbed mutant p53 gain of function (GOF). Here, we discuss possible ways in which mutant p53 may modulate the microenvironment in order to promote tumorigenesis. We thus propose that mutant p53 may serve as a key player in the modulation of the tumor–stroma crosstalk in a way that benefits the tumor. Further elucidation of these ‘recruitment’ processes, dictated by mutant p53, may be utilized for tailoring personalized therapeutic approaches for patients with tumors that harbor p53 mutation.
Collusive Algorithms as Mere Tools, Super-tools or Legal Persons
Authors: Zheng Guan , Wu Hong 
Published: July 2019

Abstract
The widespread use of algorithmic technologies makes rules on tacit collusion, which are already controversial in antitrust law, more complicated. These rules have obvious limitations in effectively regulating algorithmic collusion. Although some scholars and practitioners within antitrust circles in the United States, Europe and beyond have taken notice of this problem, they have failed to a large extent to make clear its specific manifestations, root causes, and effective legal solutions. In this article, the authors make a strong argument that it is no longer appropriate to regard algorithms as mere tools of firms, and that the distinct features of machine learning algorithms as super-tools and as legal persons may inevitably bring about two new cracks in antitrust law. This article clarifies the root causes why these rules are inapplicable to a large extent to algorithmic collusion particularly in the case of machine learning algorithms, classifies the new legal cracks, and provides sound legal criteria for the courts and competition authorities to assess the legality of algorithmic collusion much more accurately. More importantly, this article proposes an efficacious solution to revive the market pricing mechanism for the purposes of resolving the two new cracks identified in antitrust law.
Can Clearcutting Reset Successional Trajectories in Upland Oak–Hickory Forests? A Case Study from Mid-Missouri
Authors: Knapp Benjamin O , Anderson Samantha E , Curtin Patrick J , Ghilardi Casey , Rives Robert G 
Published: July 2019

AbstractSecuring oak regeneration is a common management challenge in the central and eastern United States. We quantified the abundance of tree species groups in clearcuts in mid-Missouri more than 30 years following harvest to determine differences in species dominance based on aspect (exposed, protected, or ridge sites). Each tree was classified as “dominant” or “suppressed” based on its relative contribution to cumulative stand stocking, following concepts of the tree–area relation. Although maples or understory species were the most abundant across all sites, oaks and hickories contributed to more than 60 percent of the dominant stems on the exposed sites. In contrast, oaks and hickories made up less than 25 percent of the dominant stems on protected and ridge sites. Results indicate that clearcutting reset the successional trajectory, from a transition to maple dominance to maintaining oak–hickory dominance, on exposed sites but not on ridge or protected sites.
Measurement of Monoclonal Immunoglobulin Protein Concentration in Serum Protein Electrophoresis: Comparison of Automated vs Manual/Human Readings
Authors: Clavijo Alex , Ryan Nathan , Xu Hongyan , Singh Gurmukh 
Published: July 2019

Abstract

Background
Protein concentration of monoclonal immunoglobulin in plasma-cell myeloma/multiple myeloma provides an estimate of the tumor mass and allows for monitoring of the response to treatment. Accurate and reproducible estimates of the monoclonal immunoglobulin concentration are important for patient care.

Objective
To address the optimum method for estimation of the concentration of monoclonal immunoglobulins.

Methods
Serum protein electrophoresis and immunofixation electrophoresis were conducted by using the Helena SPIFE Touch instrument. Estimation of the protein concentration of monoclonal immunoglobulin in the gamma region by computer-assisted reading was compared with the reading by technologists and pathology residents, in 300 gels. The data were compared using t-testing and analysis of variance.

Results
Computer-generated readings had a consistent positive bias. The correlation coefficient of the average reading by technologists and residents with the computer generated value was 0.997. The average positive bias by the computer reading was 0.29 g per dL. The intercept on the regression analysis was 0.22 g per dL. The reading by the computer was significantly higher than each of the human-interpreted readings. The readings by the 3 human groups were not significantly different amongst them. The main reason for the higher reading by the computer was inclusion of a greater area on the anodal size of the peak on the densitometric scan.

Conclusions
Human- and computer-interpreted readings of the protein concentration of monoclonal immunoglobulin have a high degree of correlation. The consistent positive bias by the computer reading occurred due to inclusion of a greater area of the densitometric scan on the anodal side of the peak. We suggest that vendors should adjust such computer programs to provide readings comparable to those generated by expert humans. We recommend manual delineation of the monoclonal peaks for measuring the concentration of monoclonal immunoglobulins.
Author identification with feature transformation method
Authors: Tamboli Mubin Shoukat , Prasad Rajesh 
Published: July 2019

Abstract
Over the last few decades, there has been tremendous growth in online communication through different types of media. Communication via the Internet is anonymous, which causes a critical issue regarding identity tracing. Authorship identification can apply to tasks such as identifying an anonymous author, detecting plagiarism, or finding a ghostwriter. Previous research has outlined the various methods and their improvements for the identification of anonymous authors based on stylometry. However, changes in the writing style of an author over a long period has not been addressed. In this article, we propose a methodology for author identification where the writing style of an author changes. The proposed methodology consists of two phases: the first will show the change in writing style of the author and in another phase the change is mitigated by a new feature normalization technique. A novel Transform Feature to Current Time function is proposed for normalization, where features are shifted to current time and made available for further classification. A machine-learning algorithm is used to identify an author candidate. The experiments of the proposed methodology conducted on a set of text samples by several authors were collected over a different time period and the results show an improvement in performance.
United States Air Force Academy Cadets’ Perceived Costs of Concussion Disclosure
Authors: Rawlins Michelle L Weber , Johnson Brian R , Register-Mihalik Johna K , DeAngelis Karin , Schmidt Julianne D , D’Lauro Christopher J 
Published: July 2019

Abstract

Introduction
Concussion is unique among sport-related injuries as effective clinical diagnosis and treatment often rely on symptom-report for clinician diagnosis and treatment. However, at-risk populations such as collegiate athletes and military academy cadets often have been shown to under-report concussions and symptoms, complicating diagnosis, treatment, and policy-based interventions. The purpose of this study was to explore factors influencing concussion reporting in United States Air Force Academy (USAFA) cadets.

Materials and Methods
Semi-structured interviews were conducted on 34 cadets (18 with concussion history; 16 without concussion history). This study was approved by the USAFA Institutional Review Board. Analysis included a five-cycle process of clarifying the topic at hand through an introduction, conducting a literature review, data collection and summarization, relating current findings to current literature, and making final interpretations. Data were summarized by creation of a codebook after reading five transcripts and identifying meaningful units. A four-person research team read and identified meaningful units individually, then met to discuss common meaningful units and codebook creation. Once the codebook was created, the lead researcher used the codebook to code all transcripts.

Results
Eight themes were generated from interview transcripts. This manuscript focuses on the perceived costs following a concussion theme and the following subthemes: perceived costs to physical fitness, military career aspirations, pilot qualifications, sport, reputation, academics, and lack of time.

Conclusions
Cadet interviews described a complex environment where concussions were often viewed as costly to future career ambitions and provided potential reasons for non-disclosure largely including disruption in daily life. Reduction in perceived and actual harms due to concussion disclosure will require not only improving clinical care, but also addressing barriers to self-disclosure. Additionally, research suggests the sooner one reports a concussion, the sooner they return to physical or military activity. Educational interventions should be designed to address the perceived costs identified from our study and educate cadets that while some costs may be reality, others may not. Secondly, it should also be stressed to cadets that the sooner one seeks medical attention following a concussion, the sooner they may return to activity. Messaging around these themes may decrease the costs associated with time removed from academics, athletics, or military activities therefore minimizing attempts at concussion self-management. Lastly, if efforts are made to improve the overall concussion disclosure stigma, cadets may increase seeking care after injury because their reputation may not be as impacted.
Normative Uncertainty and the Dependence Problem
Authors: Podgorski Abelard 
Published: July 2019

AbstractIn this paper, I enter the debate between those who hold that our normative uncertainty matters for what we ought to do, and those who hold that only our descriptive uncertainty matters. I argue that existing views in both camps have unacceptable implications in cases where our descriptive beliefs depend on our normative beliefs. I go on to propose a fix which is available only to those who hold that normative uncertainty matters, ultimately leaving the challenge as a threat to recent skepticism about such views.
Truncated γ-exponential models: evaporation and mass-segregation effects in the bi-component system
Authors: Gomez-Leyton Yuvineza J , Velazquez Luisberis 
Published: July 2019

ABSTRACT
The γ-exponential models were previously proposed as a phenomenological attempt to characterize the properties of stellar systems with a quasi-stationary evolution under the incidence evaporation, e.g. globular clusters. They represent a parametric family of distributions that unify profiles with isothermal cores and polytropic haloes, thus providing a suitable generalization for several models available in the literature. We start our discussion revisiting some results concerning the case of single-mass systems. In particular, we emphasized that these models predict the existence of a new type of collective phenomenon: the asymptotic gravothermal collapse. This gravitational instability differs from the normal gravothermal collapse (e.g. the one associated with isothermal model) because it requires that the system releases an infinite amount of energy. Afterwards, we enter to analyse how a mass spectrum modifies the thermodynamics of these models, in particular, the associated collective phenomena. Although the theoretical description concerns to any multimass system, our computational study addresses the simplest case: the bi-component system. This analysis allows a major understanding about the thermodynamics of stellar systems under the presence of evaporation and mass segregation. For the present models, the growth of mass segregation does not affect the system evaporation disruption but favours gravothermal collapse, e.g. it tends to reduce the energy interval of stability by increasing the lower bound critical energy associated with this collective phenomenon. Extreme cases appear under certain conditions, where gravothermal collapse changes its character from asymptotic to normal.
A colour-excess extinction map of the southern Galactic disc from the VVV and GLIMPSE surveys
Authors: Soto M , Barbá R , Minniti D , Kunder A , Majaess D , Nilo-Castellón J L , Alonso-García J , Leone G , Morelli L , Haikala L , Firpo V , Lucas P , Emerson J P , Moni Bidin C , Geisler D , Saito R K , Gurovich S , Contreras Ramos R , Rejkuba M , Barbieri M , Roman-Lopes A , Hempel M , Alonso M V , Baravalle L D , Borissova J , Kurtev R , Milla F 
Published: July 2019

Abstract
An improved high-resolution and deep $A_{K_{s}}$ foreground dust extinction map is presented for the Galactic disc area within 295° ≲ l ≲ 350°, −1.0° ≲ b ≲ +1.0°. At some longitudes the map reaches up to |b| ∼ 2.25°, for a total of ∼148 deg2. The map was constructed via the Rayleigh–Jeans colour excess (RJCE) technique based on deep near-infrared (NIR) and mid-infrared (MIR) photometry. The new extinction map features a maximum bin size of 1 arcmin, and relies on NIR observations from the Two Micron All-Sky Survey (2MASS) and new data from ESO’s Vista Variables in the Vía Láctea (VVV) survey, in concert with MIR observations from the Galactic Legacy Infrared Mid-Plane Survey Extraordinaire. The VVV photometry penetrates ∼4 mag fainter than 2MASS, and provides enhanced sampling of the underlying stellar populations in this heavily obscured region. Consequently, the new results supersede existing RJCE maps tied solely to brighter photometry, revealing a systematic underestimation of extinction in prior work that was based on shallower data. The new high-resolution and large-scale extinction map presented here is readily available to the community through a web query interface.
Observable tests of self-interacting dark matter in galaxy clusters: BCG wobbles in a constant density core
Authors: Harvey David , Robertson Andrew , Massey Richard , McCarthy Ian G 
Published: July 2019

ABSTRACT
Models of cold dark matter (CDM) predict that the distribution of dark matter in galaxy clusters should be cuspy, centrally concentrated. Constant density cores would be strong evidence for beyond CDM physics, such as self-interacting dark matter (SIDM). An observable consequence would be oscillations of the brightest cluster galaxy (BCG) in otherwise relaxed galaxy clusters. Offset BCGs have indeed been observed – but only interpreted via a simplified, analytic model of oscillations. We compare these observations to the BAryons and HAloes of MAssive Sysmtes (BAHAMAS)–SIDM suite of cosmological simulations, which include SIDM and a fully hydrodynamical treatment of star formation and feedback. We predict that the median offset of BCGs increases with the SIDM cross-section, cluster mass, and the amount of stellar mass within 10 kpc, while CDM exhibits no trend in mass. Interpolating between the simulated cross-sections, we find that the observations (of 10 clusters) are consistent with CDM at the ∼1.5σ level, and prefer cross-section σ/m < 0.12(0.39) cm2 g−1 at 68 per cent (95 per cent) confidence level. This is on the verge of ruling out velocity-independent dark matter self-interactions as the solution to discrepancies between the predicted and observed behaviour of dwarf galaxies, and will be improved by larger surveys by Euclid or Super-pressure Balloon-borne Imaging Telescope (SuperBIT).
Numerical convergence of simulations of galaxy formation: the abundance and internal structure of cold dark matter haloes
Authors: Ludlow Aaron D , Schaye Joop , Bower Richard 
Published: July 2019

ABSTRACT
We study the impact of numerical parameters on the properties of cold dark matter haloes formed in collisionless cosmological simulations. We quantify convergence in the median spherically averaged circular velocity profiles for haloes of widely varying particle number, as well as in the statistics of their structural scaling relations and mass functions. In agreement with prior work focused on single haloes, our results suggest that cosmological simulations yield robust halo properties for a wide range of gravitational softening parameters, ϵ, provided: (1) ϵ is not larger than a ‘convergence radius’, rconv, which is dictated by two-body relaxation and determined by particle number, and (2) a sufficient number of time-steps are taken to accurately resolve particle orbits with short dynamical times. Provided these conditions are met, median circular velocity profiles converge to within ≈10 per cent for radii beyond which the local two-body relaxation time-scale exceeds the Hubble time by a factor $\kappa \equiv t_{\rm relax}/t_{\rm H}\rm{\,\, \buildrel\gt \over \sim \,\,}0.177$, with better convergence attained for higher κ. We provide analytic estimates of rconv that build on previous attempts in two ways: first, by highlighting its explicit (but weak) softening-dependence and, second, by providing a simpler criterion in which rconv is determined entirely by the mean inter-particle spacing, l, for example better than 10 per cent convergence in circular velocity for $r\rm{\,\, \buildrel\gt \over \sim \,\,}0.05\, l$. We show how these analytic criteria can be used to assess convergence in structural scaling relations for dark matter haloes as a function of their mass or maximum circular speed.
Time variations of H2O and SiO masers in the proto-Planetary Nebula OH 231.8+4.2
Authors: Kim Jaeheon , Cho S-H , Bujarrabal V , Imai H , Dodson R , Yoon D-H , Zhang B 
Published: July 2019

Abstract
H2O (22 GHz) and SiO masers (43, 86, 129 GHz) in the bipolar proto-planetary nebula OH 231.8+4.2 were simultaneously monitored using the 21-m antennas of the Korean VLBI Network in 2009–2015. Both species exhibit periodic flux variations that correlate with the central star’s optical light curve, with a phase delay of up to 0.15 for the maser flux variations with respect to the optical light curve. The flux densities of SiO v = 2, J = 1→0 and H2O masers decrease with time, implying that they may disappear in 10–20 years. However, there seems to have been a transient episode of intense H2O maser emission around 2010. We also found a systematic behaviour in the velocity profiles of these masers. The velocities of the H2O maser components appear to be remarkably constant, suggesting ballistic motion for the bipolar outflow in this nebula. On the other hand, those of the SiO maser clumps show a systematic radial acceleration of the individual clumps, converging to the outflow velocity of the H2O maser clumps. Measuring the full widths at zero power of the detected lines, we estimated the expansion velocities of the compact bipolar outflow traced by H2O maser and SiO thermal line, and discussed the possibility of the expanding SiO maser region in the equatorial direction. All of our analyses support that the central host star of OH231.8 is close to the tip of the AGB phase, and that the mass-loss rate recently started to decrease because of incipient post-AGB evolution.