bluuebunny/crossref_metadata_2025_split huggingface dataset:
How to build your team for innovation? A cross‐level mediation model of team personality, team climate for innovation, creativity, and job crafting
Authors: Xu Xiaohong , Jiang Lixin , Wang Hai‐Jiang 
Published: May 2019

Although multiple theories propose that team proactive personality shapes team climate for innovation, this theoretical proposition is yet to be tested by empirical studies. Drawing upon multiple theories (e.g., sense‐making theory and theories regarding social norms), we hypothesized a cross‐level mediation model of the effects of different operationalizations of team proactive personality on team climate for innovation, as well as individual creative performance and job crafting. We tested our hypothesized model using a 2‐wave longitudinal design collecting data from a sample of 187 employees and their supervisors nested within 38 teams from an Information Technology company. The results of multilevel mediation path analysis indicated that team proactive personality (i.e., mean, minimum, and maximum) was significantly and positively related to team climate for innovation. Further, team proactive personality at Time 1 exerted a cross‐level influence on individual creative performance (rated by supervisors) and job crafting at Time 2, through team climate for innovation. Finally, different operationalizations (mean, maximum, minimum, and standard deviation) of team proactive personality revealed differential relationships with team climate for innovation. These findings suggest that team proactive personality can influence outcomes at different levels of analyses. Theoretical and practical implications of these findings are discussed.Practitioner points

Team proactive personality (i.e., mean, maximum, and minimum) positively related to team climate for innovation.

Team climate for innovation positively related to both individual creativity and job crafting.

Team climate for innovation mediated the top‐down effects of team proactive personality on individual creativity and job crafting.

Employers may consider proactive personality as one criterion at the stages of selecting and staffing of team members for creative jobs and creative team projects.
Effects of ozone treatment on the quality of kiwifruit during postharvest storage affected by Botrytis cinerea and Penicillium expansum
Authors: Luo Anwei , Bai Junqing , Li Rui , Fang Yimeng , Li Lin , Wang Dan , Zhang Lu , Liang Jin , Huang Tianzi , Kou Liping 
Published: May 2019

AbstractThe objective was to reveal the effects of ozone treatment on quality maintenance and resistance to Botrytis cinerea and Penicillium expansum in kiwifruit during postharvest storage. Kiwifruits were treated with 79.44 ppm gaseous ozone for 1 hr once a day for 7 day at 0°C to determine the effects of ozone treatment on the quality and disease incidence caused by B. cinerea and P. expansum in vivo and the growth of B. cinerea and P. expansum in vitro. Ozone treatment significantly reduced the disease incidence of kiwifruit and inhibited the mycelial development and spore germination of B. cinerea and P. expansum. High levels of fruit firmness and titratable acidity were maintained in the ozone‐treated kiwifruit, and the activities of the defence‐related enzymes were remarkably enhanced. Therefore, ozone treatment may be an effective method to maintain the quality of kiwifruit and control its decay during postharvest storage.
Comparing Lead Users to Emergent‐Nature Consumers as Sources of Innovation at Early Stages of New Product Development
Authors: Hamdi‐Kidar Linda , Keinz Peter , Le Nagard Emmanuelle , Vernette Eric 
Published: May 2019

The large potential of lead users (LUs) in developing innovative and radically new product concepts is well established in the literature. However, in a widely acknowledged study, Hoffman et al. introduced the new concept of emergent‐nature consumers (ENCs) and showed the superiority of this group of individuals over LUs in developing new product concepts. Consequently, they postulated ENCs to be “the right consumers” to be integrated in new product development processes. In this article, we critically reflect and build on Hoffman et al.'s study and further investigate the promise of the ENC concept as compared to the LU concept. In a pilot study, we replicated the study by Hoffman and colleagues: We conducted a crowdsourcing competition and asked for concepts for new services; those concepts had been generated collectively by the participants and had been assessed by a consumer crowd. In the main study, the participants of a crowdsourcing competition submitted individually generated concepts for products, which were evaluated by industry experts. Across both studies, using different empirical methods in two different contexts, and in contrast to Hoffman et al.'s work, we find support for LUs outperforming ENCs (as well as average users) in generating the commercially most promising concepts. Thus, our insights reinforce the existing user innovation literature and the notion of LUs being the primary source of new product/service concepts.
Comparative lipidomic studies of Scenedesmus sp. (Chlorophyceae) and Cylindrotheca closterium (Bacillariophyceae) reveal their differences in lipid production under nitrogen starvation
Authors: Wang Song , Sirbu Diana , Thomsen Laurenz , Kuhnert Nikolai , Ullrich Matthias S. , Thomsen Claudia 
Published: May 2019

Microalgae are a promising resource for the highly sustainable production of various biomaterials (food and feed), high‐value biochemicals, or biofuels. However, factors influencing the valued lipid production from oleaginous algae require a more detailed investigation. This study elucidates the variations in lipid metabolites between a marine diatom (Cylindrotheca closterium) and a freshwater green alga (Scenedesmus sp.) under nitrogen starvation at the molecular species level, with emphasis on triacylglycerols using liquid chromatography–electrospray ionization mass spectrometry techniques. A comprehensive analysis was carried out by comparing the changes in total lipids, growth kinetics, fatty acid compositions, and glycerolipid profiles at the molecular species level at different time points of nitrogen starvation. A total of 60 and 72 triacylglycerol molecular species, along with numerous other polar lipids, were identified in Scenedesmus sp. and C. closterium, respectively, providing the most abundant triacylglycerol profiles for these two species. During nitrogen starvation, more triacylglycerol of Scenedesmus sp. was synthesized via the “eukaryotic pathway” in the endoplasmic reticulum, whereas the increase in triacylglycerol in C. closterium was mainly a result of the “prokaryotic pathway” in the chloroplasts after 96 h of nitrogen starvation. The distinct responses of lipid synthesis to nitrogen starvation exhibited by the two species indicate different strategies of lipid accumulation, notably triacylglycerols, in green algae and diatoms. Scenedesmus sp. and Cylindrotheca closterium could serve as excellent candidates for the mass production of biofuels or polyunsaturated fatty acids for nutraceutical purposes.
Evidence for vertical transmission ofMycoplasma haemocanis, but notEhrlichia ewingii, in a dog
Authors: Lashnits Erin , Grant Sandra , Thomas Brittany , Qurollo Barbara , Breitschwerdt Edward B. 
Published: May 2019

AbstractA 2‐year‐old female intact pregnant Beagle was evaluated after the owner surrendered her to a shelter. Prepartum and 2 months postpartum at the time of routine spay, the dam was whole‐blood polymerase chain reaction (PCR) positive forEhrlichia ewingii. She was also whole‐blood PCR positive forMycoplasma haemocanisprepartum and continuously for 5 months thereafter. The dam delivered 5 healthy puppies, 1 of which was whole‐blood PCR positive forM. haemocanis. All 5 puppies had antibodies againstEhrlichiaspp. at 1 month of age but not thereafter, and all puppies wereEhrlichiaspp. PCR negative for 5 months of follow‐up. Therefore, this study supports a potential role for vertical transmission in the maintenance ofM. haemocanisin dogs as reservoir hosts. In contrast, in this case there was no evidence thatE. ewingiiwas transmitted transplacentally or during the perinatal period.
Living the high life: Could gut microbiota matter for adaptation to high altitude?
Authors: Mazel Florent 
Published: May 2019

AbstractAt high altitude, the reduced availability of thermal energy and oxygen poses major challenges to organisms. Different species or populations have evolved similar solutions to these challenges, such as blood flow regulation in animals (Bouverot, 1985). Previous studies investigating such convergent adaptations have primarily looked at changes in host genomes (e.g., see Scheinfeldt & Tishkoff, 2010), but have rarely considered the potential role of the gut microbiome in mediating host adaptation. As gut microbes can indirectly regulate host blood pressure (Pluznick, 2014) and energy intake efficiency, it has been hypothesized that they could help maintain normal energy production and/or optimize nutritional assimilation in high‐altitude hypoxic environments (e.g., Li & Zhao, 2015). However, it has been hard to (a) show that there is a direct effect of altitude on the gut microbiota, because of the many potential confounding effects of altitude (e.g., diet is correlated to altitude, as well as to the microbiome) and to (b) understand the mechanisms by which the microbiota could mediate host hypoxic and thermoregulatory stresses. In this issue of Molecular Ecology, Suzuki, Martins, and Nachman (2018) show that, independently of diet, taxonomic composition and functions of mouse gut microbiota converge in independent high‐altitude environments and propose the intriguing hypothesis that some of these functional convergences might be beneficial to their host.
A graph deep learning method for short‐term traffic forecasting on large road networks
Authors: Zhang Yang , Cheng Tao , Ren Yibin 
Published: May 2019

AbstractShort‐term traffic flow prediction on a large‐scale road network is challenging due to the complex spatial–temporal dependencies, the directed network topology, and the high computational cost. To address the challenges, this article develops a graph deep learning framework to predict large‐scale network traffic flow with high accuracy and efficiency. Specifically, we model the dynamics of the traffic flow on a road network as an irreducible and aperiodic Markov chain on a directed graph. Based on the representation, a novel spatial–temporal graph inception residual network (STGI‐ResNet) is developed for network‐based traffic prediction. This model integrates multiple spatial–temporal graph convolution (STGC) operators, residual learning, and the inception structure. The proposed STGC operators can adaptively extract spatial–temporal features from multiple traffic periodicities while preserving the topology information of the road network. The proposed STGI‐ResNet inherits the advantages of residual learning and inception structure to improve prediction accuracy, accelerate the model training process, and reduce difficult parameter tuning efforts. The computational complexity is linearly related to the number of road links, which enables citywide short‐term traffic prediction. Experiments using a car‐hailing traffic data set at 10‐, 30‐, and 60‐min intervals for a large road network in a Chinese city shows that the proposed model outperformed various state‐of‐the‐art baselines for short‐term network traffic flow prediction.
Natural variations of growth thermo‐responsiveness determined by SAUR26/27/28 proteins in Arabidopsis thaliana
Authors: Wang Zhixue , Yang Leiyun , Liu Zhenhua , Lu Minghui , Wang Minghui , Sun Qi , Lan Yiheng , Shi Tieliu , Wu Dianxing , Hua Jian 
Published: May 2019

Summary

How diversity in growth thermo‐responsiveness is generated for local adaptation is a long‐standing biological question. We investigated molecular genetic basis of natural variations in thermo‐responsiveness of plant architecture in Arabidopsis thaliana.

We measured the extent of rosette architecture at 22°C and 28°C in a set of 69 natural accessions and determined their thermo‐responsiveness of plant architecture. A genome‐wide association study was performed to identify major loci for variations in thermo‐responsiveness.

The SAUR26 subfamily, a new subfamily of SAUR genes, was identified as a major locus for the thermo‐responsive architecture variations. The expression of SAUR26/27/28 is modulated by temperature and PIF4. Extensive natural polymorphisms in these genes affect their RNA expression levels and protein activities and influence the thermo‐responsiveness of plant architecture. In addition, the SAUR26 subfamily genes exhibit a high variation frequency and their variations are associated with the local temperature climate.

This study reveals that the SAUR26 subfamily is a key variation for thermo‐responsive architecture and suggests a preference for generating diversity for local adaptation through signaling connectors.
Immune‐related gene expression profiles of hypothermia adipocytes: Implications for Bell's palsy
Authors: Zhang Wenjuan , Xu Lei , Luo Tingting , Zhao Bin , Wu Feng , Li Xianqi 
Published: May 2019

AbstractObjectiveTo identify immune‐related gene expression profiles of adipocytes under low temperatures with RNA sequencing as a model for Bell's palsy implications.MethodsAdipocytes were harvested from the white adipose tissue of male Sprague‐Dawley rats and cultured under different acute‐grade cold exposure conditions of 30, 20, and 10°C, and their genomes were sequenced for RNA sequencing analysis. The differentially expressed genes (DEGs) were validated with reverse transcription polymerase chain reaction.ResultsIn total, 55 (35 upregulated and 20 downregulated), 121 (76 upregulated and 45 downregulated), and 92 (64 upregulated and 28 downregulated) DEGs were identified under 30, 20, and 10°C compared with the control, respectively. KEGG and GO analysis revealed that the DEGs were considerably enriched in immune‐related pathways (leukocyte transendothelial migration and platelet activation) and infection (bacterial invasion of epithelial cells and Salmonella infection). The levels of key inflammatory chemokines (CSF1, CXCL1, CCL2, and CCL7) were enhanced after cold exposure.ConclusionThese findings broaden our understanding of the immune responses to cold exposure in adipocytes. The molecular profiles of adipocyte immune function will help clarify the potential mechanism impacting myelin, which might contribute to the development of strategies to control Bell's palsy.
Transmural unipolar electrogram change occurs within 7 s at the left atrial posterior wall during pulmonary vein isolation
Authors: Tomlinson David R. , Myles Madison , Stevens Kara N. , Streeter Adam J. 
Published: May 2019

AbstractBackgroundTo assess occurrence of a histologically validated measure of transmural (TM) atrial ablation—pure R unipolar electrogram (UE) morphology change—at first‐ablated left atrial posterior wall (LAPW) sites during contact force (CF)‐guided pulmonary vein isolation (PVI).MethodsObjectively annotated VISITAG™ Module and CARTOREPLAY™ (Biosense Webster Inc., Diamond Bar, CA, USA) UE morphology data were retrospectively analyzed in 23 consecutive patients undergoing PVI under general anesthesia.ResultsPVI without spontaneous/dormant recovery was achieved in all, employing 16.3 (3.2) min of radiofrequency (RF; 30 W) energy. All first‐ablated LAPW sites demonstrated RS UE morphology preablation, with RF‐induced pure R UE morphology change in 98%. Time to pure R UE morphology was significantly shorter at left‐sided LAPW sites (4.9 [2.1] vs 6.7 [2.5] s; P = .02), with significantly greater impedance drop (median 13.5 vs 9.9 Ω; P = .003). Importantly, neither first‐site RF duration (14.9 vs 15.0 s) nor maximum ablation catheter tip distance moved (during RF) was significantly different, yet the mean CF was significantly higher at right‐sided sites (16.5 vs 11.2 g; P = .002). Concurrent impedance and objectively annotated bipolar electrogram (BE) data demonstrated ∼6‐8 Ω impedance drop and ∼30% BE decrease at the time of first pure R UE morphology change.ConclusionsUsing objective ablation site annotation, UE morphology evidence of TM RF effect was demonstrated far sooner than considered biologically possible according to the “conventional” 20‐40 s RF per‐site approach, with significantly greater ablative effect evident at left‐sided sites. This novel methodology represents a scientifically more rigorous foundation toward future research into the biological effects of RF ablation in vivo.
Retail Credit Scoring using Fine-Grained Payment Data
Authors: Tobback Ellen , Martens David 
Published: May 2019

Summary
Banks are continuously looking for novel ways to leverage their existing data assets. A major source of data that has not yet been used to the full extent is massive fine-grained payment data on the bank’s customers. In the paper, a design is proposed that builds predictive credit scoring models by using the fine-grained payment data. Using a real life data set of 183 million transactions made by 2.6 million customers, we show that the scalable implementation that is put forward leads to a significant improvement in the receiver operating characteristic area under the curve, with only seconds of computation needed. When investigating the 1% riskiest customers, twice as many defaulters are detected when using the payment data. Such an improvement has a big effect on the overall working of the bank, from applicant scoring to minimum capital requirements.
Sediment petrography, mineralogy and geochemistry of the Miocene Islam Dağ Section (Eastern Azerbaijan): Implications for the evolution of sediment provenance, palaeo‐environment and (post‐)depositional alteration patterns
Authors: Baldermann Andre , Abdullayev Elshan , Taghiyeva Yelena , Alasgarov Alasgar , Javad‐Zada Zohrab 
Published: May 2019

AbstractThe reconstruction of regional long‐term patterns recorded in marine sedimentary successions of the Eastern Paratethys is important in understanding the role of Cenozoic climate change and orogenic activity on the depositional environment and sedimentation dynamics in Western Asia. In this study, the environmental conditions in the early to middle Miocene (Islam Dağ section) in eastern Azerbaijan are elucidated using petrographic–mineralogical relations, detrital indicators, weathering indices and δ13C and δ18O signatures of organic‐rich (total organic carbon: ca 3 to 6 wt. %) argillites. Sedimentary facies and chemical proxies (Na/K, K/Al, Si/Al, Ti/Al ratios, chemical index of alteration values) indicate arid conditions, reduced weathering rates in the hinterland and sediment deposition in an euhaline and poorly oxygenated deep‐water basin during the early Miocene, followed by a shift to humid conditions, higher weathering rates and an oxygenated water column in the mid‐early Miocene. Long‐term aridification and deposition of gypsiferous and calcareous argillites under generally more oxygenated, euhaline to polyhaline conditions in a lacustrine or restricted shelf setting until the middle Miocene is evidenced by gradual changes in element ratios and the chemical index of alteration. Discriminant function analysis suggests the Russian Platform, drained by the Palaeo‐Volga and Palaeo‐Don river systems, to be the source area for the siliciclastic input throughout the Miocene, although a minor contribution of volcanogenic detritus and mafic components from the Greater Caucasus is possible. The C–S–Fe associations and increasing Fe/Al ratios towards the middle Miocene support the concept of continuous influx of detrital Fe and total organic carbon. The formation of ferruginous smectite from alteration of volcanic ash layers could have affected the preservation of total organic carbon and therefore the sedimentary C and Fe budget in the Eastern Paratethys basins. Palaeo‐climatic reconstructions based on δ13C (−34·5 to +1·7‰ Vienna Pee Dee Belemnite) and δ18O (−34·7 to −4·8‰ Vienna Pee Dee Belemnite) records of authigenic carbonates should be made with great caution, as the pristine marine signatures may be affected by the oxidation of organic matter and meteoric diagenesis.
Comparative “virtual biopsies” of normal skin and skin lesions using vibrational optical coherence tomography
Authors: Silver Frederick H. , Shah Ruchit G. , Richard Michael , Benedetto Dominick 
Published: May 2019

AbstractBackgroundIncreased tissue stiffness (also termed modulus) has been shown to be a characteristic of potential tumor metastasis. Measured values of the stiffness of tumors and cancer cells are reported in the literature to increase compared to neighboring normal tissues. Yet the relationship between the mechanical properties of cells and the extracellular matrix has yet to be correlated with the histopathology of cancerous lesions.Materials and MethodsWe have developed a technique to do virtual biopsies of skin lesions by combining images made using optical coherence tomography with stiffness measurements made simultaneously using vibrational analysis. The technique is termed vibrational optical coherence tomography (VOCT).ResultsIn this paper, we report that precancerous and cancerous lesions are characterized by changes in both the morphology and stiffness of the cellular components of the skin. The ratio of the peak heights that correspond to the epidermal (40‐60Hz) and dermal (140‐160 Hz) resonant frequencies appear to be different for benign and cancerous or precancerous lesions compared with normal skin and scar.ConclusionsCell‐to‐cell and epidermal‐to‐dermal interactions may be very important in evaluating the potential of skin lesions to become malignant. These interactions can be evaluated using VOCT, a new technique for performing “virtual biopsies” of skin lesions.
A potential role of TLR2 in xenograft rejection of porcine iliac endothelial cells: An in vitro study
Authors: Chen Jicheng , Gao Hanchao , Chen LinLin , Wang Xisheng , Song Zongpei , Cooper David K. C. , Qu Zepeng , Cai Zhiming , Mou Lisha 
Published: May 2019

AbstractBackgroundPorcine vascular endothelial cells are a major participant in xenograft rejection. The Toll‐like receptor 2 (TLR2) pathway plays an important role in both innate and adaptive immunity. The specific role of TLR2 in the response to a xenograft has not been reported. Whether the TLR2 pathway in pig vascular endothelial cells is involved in acute rejection needs to be investigated, and the mechanism is explored.MethodsWe used a modified antibody‐dependent complement‐mediated cytotoxicity (ADCC) assay to conduct in vitro experiments. In porcine iliac artery endothelial cells (PIECs), siRNA was used to knock down the expression of TLR2, CXCL8, and CCL2. The effect of human serum or inactivated human serum on the expression of TLR2 was analyzed by real‐time PCR and Western blotting, and transwell assays were used to assess the chemotactic efficiency of PIECs on human monocyte‐macrophages (THP‐1 cells) and human neutrophils. The downstream signaling pathways activated by human serum were detected by Western blotting, and the regulation of proinflammatory chemokines and cytokines by TLR2 signaling was assessed by real‐time PCR and ELISA.ResultsTLR2 was significantly upregulated in PIECs after exposure to human serum, and porcine proinflammatory chemokines, CXCL8 and CCL2, were induced, at least partially, in a TLR2‐dependent pattern; the upregulated chemokines participated in the chemotaxis of human neutrophils and THP‐1 cells across the species barrier.Conclusions(i) TLR2 is significantly upregulated in PIECs by human serum, (ii) the elevated TLR2 participates in the chemotaxis of inflammatory cells through the secretion of chemokine CCL2 and CXCL8, and (iii) blockade of TLR2 would be beneficial for xenograft survival.