bluuebunny/crossref_metadata_2025_split huggingface dataset:
PATHOGENIC BACTERIA ISOLATED FROM COCKROACHES FOUND IN FOOD PREMISES
Authors: Wahab Anis Husna , Mohd Tahir Mohd Pozi , Mohamed Emida 
Published: October 2019

Cockroaches play an important role in transmission of different diseases either mechanically and biological because they spread and harbor various species of microorganism. This study was carried out to isolate the pathogenic bacteria from external and internal body of cockroaches at food premises. A total of 48 cockroaches, 32 of Periplanetta americana and 16 of Blatta orientalis, were collected at food premises in Shah Alam, Selangor, Malaysia. Medically important bacteria were isolated from external and internal surface by using microbial technique. From the collected Periplanetta americana and Blatta orientalis, E.coli,Salmonella species, Shigella species, and Staphylococcus were isolated and identified in their selective media such as nutrient agar, MacConkey agar, and Xylone Lysine Deoxycholate (XLD) agar using microbial technique. The data obtained from the study emphasized that cockroaches may play an important role in the transmission of pathogenic bacteria to human. The presence of cockroaches at food premises maybe due to unhygienic environment. Thus it may pose as a safety issue as they may carries of pathogenic microorganisms that can threaten the health of individuals.
OPTIMIZATION OF SOLAR FENTON OXIDATION AND COMPARISON OF RECYCLE WET AND DRIED FENTON SLUDGE IN TREATING PALM OIL MILL SECONDARY EFFLUENT
Authors: Shahrifun Nurul Shairah Ahmad , Hussain Hazilia , Omar Qistina 
Published: October 2019

This paper reports on the potential use of wet and dried Fenton sludge in replacement of the ferrous salt in treating Palm Oil Mill Secondary Effluent (POMSE) sample. The aims of this study were to characterize the Fenton sludge and to compare the performances of wet and dried Fenton sludge as iron sources in treating POMSE. The Fenton sludge were used to replace the Ferrous salt in R1- R5 and the results were compared with treatment used only H2O2 (non-catalyze). The optimum condition was run prior to tests and was found to be pH 3, H2O2/COD 1.59 (weight ratio) and Fe/COD 1.0 (weight ratio). Findings showed the removal of COD, color, turbidity and TSS in recycle wet Fenton sludge were ranging from 62% - 79%, 24% - 50%, 46% -74% and 62% - 73% respectively, while dried Fenton sludge treatment were ranging from 34% - 40%, 26% - 43%, 39% - 45% and 54% - 57% respectively. On the other hand, treatment with H2O2 showed approximately 60% removal for both COD and color while approximately 79% for both turbidity and TSS respectively. In conclusion recycled wet Fenton sludge treatment demonstrated higher removal of contaminant compared to the recycle dried Fenton sludge treatment.
MODIFICATION OF BSF LAYER IN BIFACIAL SOLAR CELL VIA PHOTOSENSITIZATION OF MOLECULES NANOSTRUCTURE
Authors: Mohd Sinin Nurul Aqidah , Ibrahim Mohd Adib , Sepeai Suhaila , Sulaiman Mohamad Yusof , Mat Teridi Mohd Asri , Ahmad Ludin Norasikin , H. Zaidi Saleem 
Published: October 2019

Surface passivation is the most significant step to keep the recombination loss at a tolerable minimum and avoid an unacceptably large efficiency loss when moving towards thinner silicon material. In this study, the modification and photosensitization on back surface field (BSF) of bifacial solar cell was investigated by using dye molecules nanostructure namely DiO. The DiO dye molecules nanostructure was passivated on SiNW and BSF layers using spin-coating method. The energy gaps of DiO dye are 2.14 eV (DiO in chloroform), 2.13 eV (DiO on silicon nanowire (SiNW)) and 2.12 eV (DiO on BSF). The time resolved photoluminescence increased with the DiO dye coated on SiNW ( 14Ï„"> = 1.24 nm) and BSF layers ( 14Ï„"> = 0.93 nm) compared to DiO dye in chloroform ( 14Ï„"> = 0.54 nm). The light trapping inside the interface layers of DiO dye/silicon indicating a slow process of charge recombination before its reach equilibrium states, it is due to interface interaction bonding within boundary layers and dye molecules nanostructure. The short circuit current density also increased about 25% from 4.44 to 5.56 mA/cm2 when applying the dye molecules nanostructure on BSF of the cell. Collection of photo carrier lead of internal and external quantum efficiency improved about 19% and 25%, respectively, is mainly due to energy transported to the junction. The photo-generated electron on DiO dye lead to improvement in the exciton dissociation efficiency leading to increase in the electrical properties.
Interpretation of mouth-bar and related lacustrine and fluvial sand bodies from the middle Green River Formation (Eocene), southern Uinta Basin, Utah
Authors: Keighley Dave , Spinnangr Øystein , Howell John , Flint Stephen 
Published: October 2019

ABSTRACT
The Uinta Basin of eastern Utah is an intermontane basin that contains an ~2-km-thick succession of mostly carbonate-rich mudrock assigned to the Eocene Green River Formation. In the southwest part of the basin, along Nine Mile Canyon and its tributary canyons, the middle member of the Green River Formation contains numerous interbedded sand bodies. Previous researchers have interpreted these sand bodies variably as lacustrine deltaic mouth bars, terminal fluvial distributary bars, and various types of fluvial (delta plain/floodplain/braid plain) bar.
Using some modern western U.S. lakes as partial analogues, and taking into account the overall lacustrine basin context of a widely fluctuating, wave-influenced, alkaline-lake shoreline, we again interpret many of the sand bodies to be fluvial in origin. Several sand bodies both truncate and are capped by brown to red-maroon and variegated weak to noncalcareous mudstone with root and desiccation structures, indicating terrestrial deposition well away from the lake shoreline. Others display steep cutbanks from which noncalcareous, inclined heterolithic stratification laterally accreted as fluvial side bars. Utilizing helicopter-based light detection and ranging (LiDAR) data, we investigated additional sand bodies that may be better examples of deltaic mouth bars. In contrast to the more commonly documented highstand progradational mouth bars of marine and open lake settings, these sand bodies are interpreted to have originated as late-lowstand or transgressive system tract fluvial channels that were then flooded and modified by waves following lake transgression. These examples illustrate that any large-scale sandy bed form present in the general vicinity of a closed basin’s fluctuating lake shore may be expected to have formed under more than one set of environmental conditions. A revised set of guidelines is therefore presented to aid in the interpretation of lacustrine deltaic mouth bars.
Symptom interval and treatment burden for patients with malignant central nervous system germ cell tumours
Authors: Hayden James , Murray Matthew J , Bartels Ute , Ajithkumar Thankamma , Muthusamy Brinda , Penn Anthony , Calaminus Gabriele , Nicholson James 
Published: October 2019

ObjectivePatients with central nervous system germ cell tumours (CNS-GCTs) commonly initially present to primary care or general paediatricians. Prolonged symptom intervals (SI) are frequently seen in CNS-GCTs and have been associated with inferior outcomes in other brain tumours. This study reviewed the clinical presentation of CNS-GCTs and examined the effect of prolonged SI.Design/Setting/Patients/OutcomesInternational multicentre 10-year retrospective study (2002–2011 inclusive), across six international paediatric oncology treatment centres. All newly diagnosed patients with CNS-GCT were included. Main outcome measure was time interval from first symptom to diagnosis.ResultsThe study cohort included 86 (58 males:28 female) patients (59 ‘germinoma’ and 27 ‘non-germinomatous’ GCTs), with tumours being pineal (n=33), suprasellar (n=25), bifocal (pineal+suprasellar; n=24) and ‘other’ site (n=4), of which 16 (19%) were metastatic. Median age at diagnosis was 14 years (0–23 years). The time to diagnosis from first symptom (SI) was 0–69 months (median 3 months, mean 9 months). A prolonged SI (>6 months) was observed in 28/86 patients (33%) and significantly associated with metastatic disease (11/28 (39%) vs 5/58 (9%); p=0.002)) at diagnosis, but not overall survival. With prolonged SI, endocrine symptoms, particularly diabetes insipidus, were more common (21/28 (75%) vs 14/58 (24%) patients; p<0.002), but raised intracranial pressure (RICP) was less frequent (4/28 (14%) vs 43/58 (74%) patients; p<0.001)) at first symptom.ConclusionsOne-third of patients with CNS-GCT have >6 months of symptoms prior to diagnosis. Delayed diagnosis is associated with metastatic disease. Early symptom recognition, particularly related to visual and hormonal disturbances in the absence of RICP, may improve timely diagnosis, reduce metastatic disease frequency and consequently reduce treatment burden and late effects.
Multicentre, randomised controlled trial of adjuvant chemotherapy in cervical cancer with residual human papilloma virus DNA following primary radiotherapy or chemoradiotherapy: a study protocol
Authors: Wang Yanhong , Ouyang Yi , Su Jingjing , Liu Jing , Cai Qunrong , Xu Qin , Bai Zhigang , Cao Xinping 
Published: October 2019

IntroductionThe role of adjuvant chemotherapy after radical radiotherapy (RT) or chemoradiotherapy (CRT) in cervical cancer awaits further confirmation. Evidences have shown that persistent human papilloma virus (HPV) DNA in exfoliated cell post-RT is a potential biomarker of subclinical residual disease and thus increases the risk of recurrence. In this prospective, multicentre, randomised controlled trial, we will use HPV DNA in exfoliated cell to identify patients with cervical cancer who received definitive RT or CRT with higher risk of relapse for adjuvant chemotherapy.Methods and analysisEligible patients with histologically confirmed cervical cancer stage IIA2 to IVA of the International Federation of Gynaecology and Obstetrics, adequate organ function and no locoregional disease or distant metastasis after completion of primary treatment will be screened for HPV DNA in exfoliated cell at 1 month post-RT. Patients with undetectable HPV DNA will undergo standard surveillance. Patients with detectable HPV DNA will be randomly assigned to either adjuvant chemotherapy with docetaxel and nedaplatin for four cycles (arm 1) or observation (arm 2). Patients will be stratified for primary treatment (RT vs CRT). The primary endpoint is relapse-free survival.Ethics and disseminationThis protocol received a favourable ethical opinion from the Ethics Committee of the Second Affiliated Hospital of Fujian Medical University on 6 February, 2018, (No. 28). The trial results will be published in peer-reviewed journals and presented in conferences. A summary of the findings will be made available to participants.Trial registration numberChiCTR-IIR-17012655; Pre-results.
Early life adversity, contact with children’s social care services and educational outcomes at age 16 years: UK birth cohort study with linkage to national administrative records
Authors: Teyhan Alison , Boyd Andy , Wijedasa Dinithi , Macleod John 
Published: October 2019

ObjectivesTo use record linkage of birth cohort and administrative data to study educational outcomes of children who are looked-after (in public care) and in need (social services involvement), and examine the role of early life factors.Setting, designProspective observational study of children from the Avon Longitudinal Study of Parents and Children (ALSPAC), which recruited pregnant women in and around Bristol, UK in the early 1990s. ALSPAC was linked to the annual Children Looked-After (CLA) Data Return and Children In Need (CIN) Census. Educational outcomes at 16 years were obtained through linkage to the National Pupil Database (NPD). These included passing 5+ good GCSEs (grades A*-C, including English and Maths). Covariates included early life adversity and social position.Participants12 868 ALSPAC participants were linked to the NPD. The sample for the main educational outcomes analyses comprised 9545 children from the ALSPAC core sample who had complete education data.ResultsOverall, of the 12 868 ALSPAC participants linked to NPD data, 137 had a CLA record and a further 209 a CIN record during adolescence. These children were more disadvantaged than their peers and had little active study participation beyond infancy. In the main educational outcomes analyses, achievement of 5+ good GCSEs was low in the CLA (OR 0.14, 95% CI 0.05 to 0.35) and CIN (0.11, 0.05 to 0.27) groups relative to their peers. Measured early life factors explained little of this difference.ConclusionsData linkage enabled the study of educational outcomes in children with social services contact. These children had substantially worse educational outcomes relative to their peers, for reasons likely to be multifactorial.
Platelet-Rich plasma Injection Management for Ankle osteoarthritis study (PRIMA): protocol of a Dutch multicentre, stratified, block-randomised, double-blind, placebo-controlled trial
Authors: Paget LDA , Bierma-Zeinstra SMA , Goedegebuure S , Kerkhoffs GMMJ , Krips R , Maas M , Moen MH , Reurink G , Stufkens SAS , de Vos RJ , Weir A , Tol JL 
Published: October 2019

IntroductionPlatelet-rich plasma (PRP) is a potentially efficacious treatment for ankle osteoarthritis (OA), but its use has not been examined in high-quality studies. Systematic reviews show that PRP injections significantly decrease pain and improve function in patients with knee OA. Ankle OA is more common than hip or knee OA in the young active population; with a prevalence of 3.4%.PRP injections in ankle OA are shown to be safe and improve quality of life over time, but no randomised controlled trial has been conducted. Our randomised controlled trial will evaluate the efficacy of PRP injections for symptom reduction and functional improvement, compared with placebo, in the treatment of ankle (talocrural) OA.Methods and analysisWe will conduct the Platelet-Rich plasma Injection Management for Ankle OA study: a multicentre, randomised, placebo-controlled trial. One hundred patients suffering from ankle OA will be randomised into two treatment groups: PRP injection or placebo (saline) injection. Both groups will receive two injections of PRP or placebo at an interval of 6 weeks. Primary outcome is the American Orthopaedic Foot and Ankle Society score at 26 weeks. Secondary outcomes determined at several follow-up moments up to 5 years, include Ankle Osteoarthritis Score, Foot and Ankle Outcome Score, pain subscale of (0–40), Visual Analogue Scale score (0–100), Ankle Activity Score (0–10), subjective patient satisfaction Short Form Health Survey-36, Global Attainment Scaling and the EuroQol-5 dimensions-3 levels utility score. A cost-effectiveness analysis will be performed at 1 year.Ethics and disseminationThe study is approved by the Medical Ethics Review Committee Amsterdam Medical Center, the Netherlands (ABR 2018–042, approved 23 July 2018) and registered in the Netherlands trial register (NTR7261). Results and new knowledge will be disseminated through the Dutch Arthritis Association (ReumaNederland), Dutch patient federation, conferences and published in a scientific peer-reviewed journal.Trial registration numberNTR7261.
Identifying and classifying anthropometric indicator for cardiovascular risk and coronary artery calcification: a protocol for a scoping review study
Authors: Frehner Caroline , Cunha Natalia Morais , Nagano Francisca Eugenia Zaina , Almeida Claudia Choma Bettega , Junior Emilton Lima 
Published: October 2019

IntroductionCardiovascular diseases are the main cause of mortality and disability worldwide, so the prevention becomes a priority in terms of public health. Therefore, it is necessary to use validated strategies to adequately identify these patients in daily clinical practice. The objective of this scope review is to comprehend and comprehensively describe the anthropometric indicators used in studies, such as such as weight, height, circumferences, lengths and skin folds, that address its association with coronary artery calcification to identify cardiovascular risk in the adult population.Methods and analysisUsing Arksey and O'Malley's scoping review methodology as a guide, our scoping review of published reviews begins by searching several databases: Cochrane Central Register of Controlled Trials in the Cochrane Library, Medline Complete (EbscoHost), Embase, LILACS (Literatura Latino-Americana e do Caribe em Ciências da Saúde-BIREME Literatura Latino-Americana e do Caribe em Ciências da Saúde)and Web of Science and Scielo. As well as, it will be searched in the International Platform of the Registry of Clinical Trials of the WHO (www.who.int/ictrp); ClinicalTrials.gov; Transforming Research into Practice. Our team has formulated search strategies and two reviewers will independently screen eligible studies for final study selection. Bibliographic data and abstract content will be collected and analysed using a tool developed iteratively by the research team.Ethics and disseminationThis protocol reports a comprehensive, rigorous and transparent methodology. This scoping review will be the first study to compare anthropometric measurements and coronary artery calcification, and thereby will contribute to the design and comparison of future studies in this field. This protocol reports a comprehensive, rigorous and transparent methodology. The results will be disseminated through a peer-reviewed publication. By identifying gaps in the current body of literature, this study can guide future research.
Protocol for a prospective, observational cohort study of awareness in mechanically ventilated patients admitted from the emergency department: the ED-AWARENESS study
Authors: Pappal Ryan D , Roberts Brian W , Mohr Nicholas M , Ablordeppey Enyo , Wessman Brian T , Drewry Anne M , Yan Yan , Kollef Marin H , Avidan Michael Simon , Fuller Brian M 
Published: October 2019

IntroductionAwareness with paralysis is a complication with potentially devastating psychological consequences for mechanically ventilated patients. While rigorous investigation into awareness has occurred for operating room patients, little attention has been paid outside of this domain. Mechanically ventilated patients in the emergency department (ED) have been historically managed in a way that predisposes them to awareness events: high incidence of neuromuscular blockade use, underdosing of analgesia and sedation, delayed administration of analgesia and sedation after intubation, and a lack of monitoring of sedation targets and depth. These practice patterns are discordant to recommendations for reducing the incidence of awareness, suggesting there is significant rationale to examine awareness in the ED population.Methods and analysisThis is a single centre, prospective cohort study examining the incidence of awareness in mechanically ventilated ED patients. A cohort of 383 mechanically ventilated ED patients will be included. The primary outcome is awareness with paralysis. Qualitative reports of all awareness events will be provided. Recognising the potential problem with conventional multivariable analysis arising from a small number of events (expected less than 10—phenomenon of separation), Firth penalised method, exact logistic regression model or penalised maximum likelihood estimation shrinkage (Ridge, LASSO) will be used to assess for predictors of awareness.Ethics and disseminationApproval of the study by the Human Research Protection Office has been obtained. This work will be disseminated by publication of peer-reviewed manuscripts, presentation in abstract form at scientific meetings and data sharing with other investigators through academically established means.
Significance of angiographic clot meniscus sign in mechanical thrombectomy of basilar artery stroke
Authors: Baik Sung Hyun , Kim Joon Whi , Kim Byung Moon , Kim Dong Joon 
Published: October 2019

IntroductionThe relationship between the occlusive clot morphology and the efficacy of mechanical thrombectomy (MT) in basilar artery occlusion (BAO) is not well known. Our aim was to evaluate the clinical significance of the clot meniscus sign in patients with acute BAO.Methods89 patients with acute BAO who underwent MT were retrospectively analyzed. The clot meniscus sign was defined as meniscoid/tram-track like antegrade side-wall contrast opacification of the thrombus. Patients were assigned to two groups based on the presence of the clot meniscus sign. The treatment and clinical outcomes were compared.ResultsThe clot meniscus sign was diagnosed in 62.9% (53/89) of the patients. The meniscus sign (+) group showed a shorter procedure time (55 vs 85 min; p=0.045), higher rate of successful recanalization (89.3% vs 63.6%, p=0.004), higher incidence of first pass effect (32.1% vs 6.1%, p=0.004), and lower number of passes (2 vs 3; p=0.042) when compared with the meniscus sign (−) group. The procedure time (OR 0.972, 95% CI 0.962 to 0.992; p=0.003) and clot meniscus sign (OR 7.920, 95% CI 1.769 to 35.452; p=0.007) were independent predictors of successful recanalization.ConclusionThe clot meniscus sign is related to high first pass effect and short procedure time and is a reliable predictor of successful recanalization in patients with acute BAO.