bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tıkayıcı Uyku Apne Sendromlu Olgularda Uyku MRG Ve Uyku Endoskopisi Bulgularının Karşılaştırılması
Authors: ÇAĞLAYAN Volkan , ÖZÇELİK KORKMAZ Müge , CİVELEK Şenol 
Published: August 2019

AMAÇ:
Çalışmamızın amacı tıkayıcı uyku apne sendrom (TUAS) lu hastalarda üst solunum yolunda
ki tıkayıcı patolojilerin değerlendirilmesine yönelik olarak geliştirilmiş olan
iki yöntemin ; uyku endoskopisi(UE) ve uyku magnetik rezonans görüntüleme (MRG)
bulgularının değerlendirilmesi ve &nbsp;karşılaştırılmasıdır.GEREÇ
VE YÖNTEM: Çalışmaya TUAS tanısı olan (AHI&gt;5) toplam
20 hasta dahil edildi. Hastaların uyku ve uyanıklık halinde MRG ile&nbsp; uvulopalatal bölge, retropalatal bölge ve dil
kökü seviyesinde anteroposterior(A-P) çap ve yüzey alan ölçümleri yapıldı. Uyku
ve uyanıklık halinde yapılan ölçüm ortalamaları karşılaştırıldı.Bu hastalara
ayrıca ameliyathane şartlarında uyku endoskopisi (UE) uygulanarak uvulopalatal,lateral
farengeal ve dil kökü bölgesinde tıkanıklık düzeyi yüzde üzerinden değerlendirildi.Elde
edilen verilerin korelasyonu istatiksel yöntemlerle değerlendirildi.BULGULAR:&nbsp; Uyku MRG
değerlendirilmesinde her üç bölgede de uyanık pozisyonda yapılan ölçümlere göre
istatiksel olarak anlamlı azalma görüldü(p&lt;0.001). UE ile uvulopalatal ve
dil kökü düzeyinde %50 ve üzeri tıkanıklık gözlenen hastaların , çap ve yüzey
ölçüm alanları ortalaması %50 den az tıkanıklık saptanan hastalara göre
istatiksel olarak anlamlı düzeyde daha düşüktü (p&lt;0.05). Bu nedenle UE ve
Uyku MRG yöntemlerinin verileri birbiri ile uyumlu olarak yorumlandı (p&lt;0.05)

SONUÇ:
UE bulgularının&nbsp; daha objektif bir teknik olan Uyku MRG
bulguları ile uyumlu olması, UE ‘nin etkinliğini göstermesi açısından önem
taşımaktadır. Bununla birlikte UE daha az ekipmanla uygulanabilmekte &nbsp;ve&nbsp;
operasyon öncesi tıkanıklığa yol açan bölgenin&nbsp; direk görüntülemesine imkan tanımaktadır.&nbsp;
Contribution de la symbiose fixatrice d’azote dans l’adaptation d’une légumineuse à des sols contrastés : le modèle Acacia spirorbis et les contraintes édaphiques extrêmes rencontrées en Nouvelle-Calédonie
Authors: Vincent Bryan 
Published: August 2019

Acacia spirorbis est une légumineuse endémique de Nouvelle-Calédonie se développant sur des sols calcaires, métallifères et volcano-sédimentaires, établissant des symbioses avec des bactéries fixatrices d’azote. Pour comprendre la contribution de la symbiose dans l’adaptation de la plante à des milieux contrastés et parfois extrêmes, nous avons évalué la fixation d’azote en conditions naturelles, caractérisé les rhizobia associés à cette plante et analysé la réponse adaptative de la plante aux éléments traces métalliques dans ses tissus racinaires, notamment au niveau des nodules.Nous avons mis en évidence que la symbiose rhizobienne fournissait plus de 80 % de l’azote total chez des populations naturelles d’A. spirorbis se développant sur des sites d’étude présentant des sols calcaires, métallifères et volcano-sédimentaires. Cette valeur est remarquable puisque, pour A. mangium, A.melanoxylon et A.mucronata, les valeurs moyennes sont respectivement de 50 %, 43 % et 58 %. Les rhizobia symbiotiques associés à A. spirorbis appartiennent aux α- et β-protéobactéries, genres Bradyrhizobium et Paraburkholderia, révélant ainsi une très large gamme de symbiontes et une faible sélectivité de partenaire. De manière remarquable, la taxonomie et le phénotype de ces souches sont structurés et adaptés aux conditions édaphiques. Enfin, les signatures chimiques des tissus internes des nodules reflètent les propriétés chimiques des sols dans lesquels ils se sont développés, indiquant une potentielle gestion des éléments traces métalliques dans ces tissus. Tous ces éléments suggèrent que la symbiose fixatrice d’azote contribue de manière significative dans l’adaptation d’Acacia spirorbis à des sols contrastés et pouvant présenter une toxicité polymétallique extrême.
Tolerance to waterlogging in Parkia gigantocarpa Ducke saplings
Authors: Viana de Andrade Júnior Waldemar , Gomes dos Santos Filho Benedito , Ferreira de Oliveira Neto Cândido , Cruz Eniel David , Shigueru Okumura Ricardo , Resende do Nascimento Vitor , Taynara da Silva Martins Jéssica , Corrêa Machado Liliane , Palheta de Sousa Diana Jhulia , Silva Teixeira Jéssica Suellen 
Published: August 2019

Cette étude se propose d’évaluer les réponses biochimiques des arbrisseaux de Parkia gigantocarpa devant l’engorgement d’eau. L’engorgement est appliqué en inondant les arbrisseaux dans des pots de 14 kg jusqu’à approximativement 5 cm au-dessus de la surface du sol. Le plan expérimental a été façonné aléatoirement et comprenait deux types d’application de l’eau (contrôle et engorgement) sur cinq périodes d’évaluation (après 0, 4, 8, 12 et 16 jours d’engorgement), avec cinq réplications par traitement. Amidon, saccharose, hydrates de carbone solubles totaux et protéines solubles totales ont été mesurés. Les arbrisseaux soumis à engorgement ont montré des réductions significatives des concentrations d’amidon (62,50 %) et de protéines solubles totales (40,98 %), en particulier dans les feuilles. L’engorgement a réduit la concentration de saccharose dans les feuilles (44,38 %), tandis que cette concentration a augmenté dans les racines (76,78 %). La concentration d’hydrates de carbone solubles a augmenté de 106,9 % dans les racines des plantes exposées à l’engorgement. Cette étude a démontré la sensibilité des arbrisseaux de Parkia gigantocarpa à l’engorgement.
Segurança Alimentar e Nutricional e fatores associados em municípios baianos de diferentes portes populacionais
Authors: Pereira Marlus Henrique Queiroz , Pereira Maria Luiza Amorim Sena , Panelli-Martins Barbara Eduarda , Santos Sandra Maria Chaves dos 
Published: August 2019

O artigo apresenta resultados da avaliação da Insegurança Alimentar (IA) em municípios da Bahia, Brasil. Aplicou-se um protocolo com 23 indicadores que medem a Segurança Alimentar e Nutricional nas quatro dimensões. Foram investigados 57 municípios de diferentes portes (pequeno, médio e grande). Foram utilizados estatísticas descritivas e os testes de Correlação de Pearson e Qui-quadrado de Pearson. Todos os municípios foram classificados em situação de IA (24,6% IA leve, 71,9% IA moderada e 3,5% IA grave), independente do porte. A IA foi identificada em todas as dimensões, mas sob uma perspectiva estatística, houve correlação significante principalmente entre indicadores da dimensão de acesso.
EVALUASI PEMANFAATAN PENGGUNAAN LAHAN BERBASIS POLA RUANG KAWASAN BUDIDAYA KABUPATEN HULU SUNGAI UTARA
Authors: Susilo Budi , Hatta Gusti Muhammad , Badaruddin Badaruddin , Kadir Syarifuddin 
Published: August 2019

Regency in addition to the limited availability of land is the presence of overlapping of Cultivation Area land use. The purpose of this study was to evaluate and assess the suitability of land use for the Spatial Patterns of Cultivation Areas of Spatial Plan and to provide policy direction in the land use utilization process. To achieve these objectives, a spatial approach was carried out. Spatial analysis was carried out by overlaying the actual land use map with the Spatial Patterns of Cultivation Areas of Spatial Plan. The next step was to evaluate the suitability of land use in Hulu Sungai Utara Regency in order to assess the suitability of the actual land use utilization of the predefined Spatial Patterns of Cultivation Areas of Spatial Plan. The results of the analysis showed that there were actual unplanned land uses in the Cultivation Area Pattern due to changes in the regional administrative boundary of 786.48 ha. Regarding the suitability of land use utilization to the Spatial Patterns of Cultivation Areas, forms of inconsistency were found. The evaluation results showed that the level of inconsistency in land use utilization in Hulu Sungai Utara Regency was in the low inconsistency category (24.68%). The policy directives in utilizing land use were controlling utilization of space, reviewing, and revising the Plan of Spatial Patterns of Cultivation Areas for Hulu Sungai Utara Regency.
Geologic, Geochemical, and Geographic Controls on NORM in Produced Water from Texas Oil, Gas, and Geothermal Reservoirs
Authors: Fisher R. Stephen 
Published: August 2019

Abstract
Naturally occurring radioactive materials (NORM) in water, sludge, and scale from Texas oil, gas, and geothermal wells can increase concern for worker safety as well as handling and disposal costs. We combined published data, new analyses of water samples, and geochemical modeling to explore controls on this radioactivity.
NORM are mainly caused by 226Ra and 228Ra, the alpha-decay daughter products of 238U and 232Th, respectively, in water and barite scale. Geologically short half-lives of the Ra isotopes, slow basinal flow velocities, short transport distances during reservoir production, and the distribution of U and Th in sedimentary reservoirs result in local lithologic variations being a major control on NORM levels. Ra activity correlates with salinity and chlorinity in Gulf Coast Frio formation water but not elsewhere in the state. Formation water composition does, however, determine the type and amount of scale that can form. Scale mineralogy, Ra/Ba and Ba/SO4 solute ratios, and reservoir temperature in turn determine the Ra activity of scale. Although our data base is small relative to the number of geologic, geochemical, and geographic variables, we find several associations of Ra isotope activity with reservoir and formation water characteristics. These associations can be used to anticipate NORM levels at the play, field, and reservoir scale.
Study on the Combination of “Online Open Course” and “Cloud Class” in the Embryology Teaching: a randomized controlled trial
Authors: Gong Linlin , Song Yang , Zhou Xin , Hu Jun , Li Jian , Chi Xinming , Zhang Liyuan , Chu Wanjiang , Hao Lihong 
Published: August 2019

Abstract
Background The purpose of this study was to illustrate that only by focusing on curriculum design and implementation can we use modern information education tools reasonably and effectively. Thus it could provide an interactive platform to improve the teaching quality and to change the traditional classroom from “passive learning” into “initiative learning”.
Methods A prospective, randomized controlled study was performed. Students of Clinical Medicine (The First and Second Affiliated Hospital) enrolled in 2017 were taken as the research subjects. 3 classes were chosen in the experimental group using the new blended teaching strategy(combination of “online open courses” and “Cloud Class”), while the other 3 classes were allocated to the control group using the traditional teaching method. A questionnaire about “evaluation of learning environment, self-learning ability and teaching effects” was administered in the experimental group after class. The whole learning process was evaluated to form formative assessment, which worked as the daily grade. All the students took an examination in the final semester.
Results The rank sum test were used to measure the statistical difference between the two groups. Comparison of academic achievement in the embryology part of final exam between the two groups, statistically significant differences could be identified (p =0.005). The results revealed that the combination teaching strategy could significantly enhance the final score of medical students compared with the control. The questionnaire showed that most students thought the new teaching method bringing a good experience of online learning. And application of smartphones not only stimulated their interests in learning, but also made perfect use of fragmented time. Reviewing videos after the class might prove more effective. Most students from the experimental group were satisfied with the new teaching strategy, and more than 90% students accepted this online and offline combination teaching module.
Conclusion The combination of “online open courses” and “Cloud Class” provides a platform for improving students’ learning ability and learning effects. These results demonstrate that the new approach appears to be a successful learning method among the fresh students.
Ras1 involved in the antifungal resistance of Candida albicans and the inhibition of farnesol on the resistance of biofilms
Authors: Wei Xin , Zuo Lulu , Chen Shengyan , Zhang Zhenzhen , Jiang Liuliu 
Published: August 2019

Abstract

Background: Farnesol enhances the susceptibility of Candida albicans biofilms to antifungals, while the molecular mechanisms of this behavior are poorly understood. RAS1 regulates the hyphal growth of C. albicans, and farnesol inhibited hyphal growth by RAS1 regulation, while the role of RAS1 in the resistance of C. albicans biofilms and the molecular mechanism of the RAS1 in the farnesol-relevant antifungal capacity to C. albicans biofilms is still unknown. The study hypothesized that Ras1 involved in the antifungal resistance of C. albicans and the inhibition of farnesol on the resistance of biofilms.
Results: The susceptibility assays showed that RAS1 over-expressing strain (RAS1OE) increased the resistance of C.albicans in both planktonic and biofilm form to antifungals, while RAS1 deletion strain (ras1Δ/Δ) reduced that to antifungals. The SMIC50 of the antifungals were increased with the mature of the biofilms formed from the mutant and the wild strains. Exogenous farnesol decreased the resistance of RAS1OE to antifungals, including fluconazole, amphotericin B, itraconazole, caspofungin, terbinafine, 5-flurocytosine and nystatin. The inhibitory effects of farnesol on the antifungal resistance of the biofilms from the RAS1OE were in accordance to almost all of the growth phases. Moreover, exogenous farnesol decreased the resistance of biofilms from RAS1OE more obviously than that from the wild strains (P<0.05). In addition, Morphological observation showed that that RAS1OE increased hyphal growth the biofilms, while ras1Δ/Δ reduced that of the biofilms. Compare to the wild-type strain, the inhibitory effects of farnesol on hyphal growth were more obvious to the RAS1OE, while less obvious to the ras1Δ/Δ. Furthermore, farnesol reduced the level of Ras1 and the expression of RAS1 of the biofilms formed from the RAS1OE strain compared with those of the untreated controls at all studied phases. Moreover, farnesol reduced the level of Ras1 and the expression of RAS1 of the biofilms formed from RAS1OE more obviously than that from the wild strains.
Conclusions: Ras1 involved in the antifungal resistance of Candida albicans, and the inhibition of farnesol on the resistance of biofilm.
Utilization of Institutional Delivery Service and Associated Factors among Women of Child Bearing Age in Bule Hora Town, West Guji Zone, Oromia Regional State, Ethiopia. Community Based Cross- Sectional Study Design, 2018
Authors: Wayessa Zelalem Jabessa , Gamede Udessa 
Published: August 2019

Abstract
Background:-Globally at least 303,000 women died during pregnancy and childbirth and every day approximately 830 women die from preventable causes related to pregnancy and childbirth. Although institutional delivery has been promoted in Ethiopia, still delivery in a health facility is far lower than other neighboring countries. The aim of this study was to assess utilization of institutional delivery service and associated factors among women of childbearing age in Bule Hora town, West Guji zone, Oromia regional state, Ethiopia
Methods: - Community-based cross-sectional study design with quantitative methods of data collection was employed from February 01 to March 30/2018. A total of 360 childbearing mothers in the Bule Hora town were involved in the study using a systematic sampling method. The instrument was pre-tested on 5% the sample at Gerba town. The data were analyzed by using binary and multivariable logistic regression and statistical associations were measured using odds ratio and 95%CI.
Results: - The prevalence of utilization of institutional delivery services in Bule hora town is 72%. According to this finding age at first pregnancy (AOR: 2.08, 95%CI: 1.768-5.620), educational status of mothers who attended secondary school and above (AOR: 4.613, 95%CI: 1.096-11.912) and primary school attended mothers (AOR:3.18, 95%CI: 2.406-3.443), educational status of husbands who attended secondary school and above (AOR: 4.91, 95%CI: 10.792-30.441)and primary school attended (AOR: 2.13, 95%CI: 8.359-12.616), spousal communication about place of delivery (AOR: 4.27, 95%CI: 1.823-10.004), husbands occupations (AOR: 2.94, 95%CI: 2.734-5.137), current antenatal care (AOR: 46.74, 95%CI: 16.778-30.210), and parity three and less children (AOR: 6.97, 95%CI: 1.305-37.212 were had a strong statistical association with utilization of institutional delivery service.
Conclusions: - The finding shows the utilization of institutional delivery service in Bule Hora town is higher than a national figure but lower than the national target of skilled delivery. Policymaker and health institutions should have to strength and create awareness of the community on the importance of institutional delivery and use of ANC service in order to screen and detect early signs of disease, followed by timely intervention.
Determinants Of Perinatal Mortality In Bahir Dar Town Governmental Health Institutions, Northwest, Ethiopia, 2019: Prospective Unmatched Case Control Study
Authors: mihretie kebadnew , WOREDE DANIEL TAREKEGN , ABUHAY TAYE 
Published: August 2019

Abstract
Background: Perinatal mortality is defined as fetal death after 28 weeks of gestation and newborn death within seven days. Globally, more than 2.6 million stillbirths and over 2.7 million early neonatal deaths are estimated to occur each year. Each day an estimated 7,300 newborns die from complication during pregnancy, child birth and further neonatal causes and 7000 stillbirth, half of this occurs after labor had started. Almost all (98%) takes place in developing countries and the magnitude of perinatal mortality in the study area was 44 per 1000 pregnancy.
Objective: The objective of this study was to identify determinants of perinatal mortality in Bahirdar town governmental health institutions.
Methods: Institutional based unmatched case control study was conducted .Cases were stillbirths and early neonatal deaths and controls were live births that were survived the first seven days after delivery. A total of 459 participants were involved in this study (153 cases and 306 controls) .Pretested, structured questioner with face to face interview was conducted and some data were also extracted using checklist from their medical records. Multivariable logistic regression analysis was done to analyze the data. A p-value of <0.05 was considered as significant at 95% confidence interval and the strength of association was measured using odds ratio.
Results: Antepartum hemorrhage (AOR 2.55,95%CI;1.23-5.26), obstructed labour (AOR 3.11,95% CI; 2.00-8.38), prematurity (AOR 3.29,95% CI;1.86-5.81), first delay (AOR 2.61,95% CI;1.56-4.39) and second delay (AOR 2.75,95% CI;1.49-5.11) were the determinants of perinatal mortality that increase risk of perinatal death. Whereas partograph use (AOR 0.24, 95% CI; 0.14-0.42) and tertiary education (AOR 0.35, 95% CI; 0.17-0.71) were found to be protective factors for perinatal mortality. Conclusion and Recommendation:The determinants of perinatal mortality were antepartum hemorrhage,prematurity, obstructed labour, first delay and second delay that were increase the risk of perinatal mortality whereas maternal tertiary education and partograph use during labour follow up were the protective factors. But the risk factors were easily identifiable and manageable with the existing health care services while health partograph use in labour follow up and educating females to tertiary education level is better, first and second delay need to avoided during
Association study between polymorphisms of XRCC1, hOGG1 in DNA repair gene and the risk of endometrial carcinoma: a meta-analysis
Authors: wen huang , xiaosi Zhou , li yi , wang zhihao 
Published: August 2019

Abstract
Objective

The association of DNA repair gene XRCC1, hOGG1 polymorphisms with susceptibility to endometrial carcinoma (EC) have been extensively studied with inconsistent results. The objective of this study was to clarify this issue by a comprehensive review and meta-analysis.

Methods

English (PubMed, Medline, Embase) and Chinese (CNKI, wanfang) electric databases were searched to collect a case-control study on the association between XRCC1 or hOGG1 gene polymorphisms and endometrial carcinoma. The retrieval time was from the database until may 1th, 2019. According to inclusion and exclusion criteria, relevant data of the final included literature were extracted and STATA 11.0 software was used for meta analysis.

Results

A total of 8 references meeting the inclusion criteria were included for analysis from the 243 retrieved literatures. The Arg399Gln polymorphism at the XRCC1 gene was associated with increased susceptibility to endometrial carcinoma (OR=1.36, 95%CI=1.23~1.51, P<0.001) in the overall population, the same results were shown in the subgroup analysis of Caucasians (OR=1.44, 95%CI=1.29~1.61, P<0.001). Ser326Cys polymorphism of the hOGG1 gene also increases the risk of endometrial carcinoma in Caucasians (OR=1.54, 95%CI=1.34~1.76, P=0.001). No publication bias was detected in this meta-analysis.

Conclusions

This meta-analysis provided evidence that the Arg399Gln polymorphism of DNA repair gene XRCC1 may increase risk of endometrial carcinoma, especially in the Caucasian. Moreover, Ser326Cys polymorphism of hOGG1 increase endometrial carcinoma risk in the Caucasian.
Integrated bioinformatics analysis reveals ASPM and CENPF with prognostic value in lung cancer
Authors: li jinghang , Zhang Jing , Huang Lin , Jin Min , Zhao Sheng 
Published: August 2019

Abstract
Lung cancer (LC) is the most frequent type of cancer in the world. But the mechanism of LC is still largely unknown. In this study, we analyzed three lung cancer gene expression microarray of different pathologic types to explore the potential candidate genes in LC by Integrated bioinformatical methods. 459 overlapped differentially expressed genes (DEGs) were explored in three GEO gene expression profile from different pathologic types of lung cancer and function annotation were analyzed. Biological process of the DEGs was enriched in regulation of vasculature development and angiogenesis. The significant molecular function of the DEGs was TGF-β receptor activity. The most significant Reactome pathway of DEGs was cell cycle and extracellular matrix organization pathway. The PPI network of the DEGs was constructed and 23 candidate hub genes were established in the network. Kaplan-Meier survival analysis show 21 genes were confirmed to associated with the prognosis of LC. The genetic alterations analysis of these genes by using cBioPortal shown ASPM has the highest genetic alteration rate of 9% in main pathological types of 3191 LC patients, and CENPF has the second highest alteration rate of 6%. ASPM and CENPF also have a significant co-occurrence relationship in LC, and they both participate in the regulation of cell cycle. In the TF -miRNA-gene network of 21 genes shown CENPF have the most significant value in the network and the most relevant TF are NFYA, E2F1 and MYC. In conclusion, this study explored several key genes about LC and analyzed potential TF of those genes, provides possible therapeutic targets and biomarker for further clinical application.