bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perlindungan Hak Cipta Dari Tindakan Pembajakan Software di Tinjau Dari Hukum Nasional
Authors: Delfiyanti  
Published: November 2024

Perkembangan teknologi melahirkan ide-ide kreatif baru dan menciptakan sesuatu yang sebelumnya tidak pernah ada menjadi ada. Dunia digital adalah media utama untuk mewujudkannya. Setiap harinya lebih dari jutaan orang menggunakan atau log in ke internet dengan berbagai macam tujuan, mulai dari riset ilmiah sampai bermain game interaktif di cyberspaces, ataupun mulai dari perdagangan atau e-commerce sampai surfing ke situs perjudian. Dalam hal ini, terdapat instrumen hukum UU No. 28 Tahun 2014 tentang Hak Cipta yang berlaku di Indonesia dimana salah satu objek yang mendapat perlindungan hak cipta adalah program komputer dalam hal ini software. Dengan ini dapat dikatakan bahwa rezim hak cipta mendapat tantangan baru setelah adanya internet dimana salah satunya perlindungan terhadap software ataupun program komputer. Namun pelanggaran terhadap perkembangan zaman ini juga semakin marak terjadi seiring dengan adanya internet. Software adalah suatu Program Komputer yang sering dijadikan sebagai objek pembajakan. Pembajakan software sudah lama menjadi permasalahan yang serius. Pembajakan software yang sering dilakukan yaitu terhadap media CD, Internet, bahkan tidak jarang pula dilakukan secara langsung dari komputer ke komputer lainnya dengan menggunakan kabel data. Akibatnya, Indonesia dihadapkan dengan dampak dan permasalahan pembajakan yang cukup signifikan dan dikenal baik di ranah internasional maupun di Indonesia sendiri. Pengaturan terkait dengan hak cipta melalui Undang-Undang Nomor 28 Tahun 2014 saat ini dianggap masih belum cukup tegas untuk mengatur mengenai tindakan pembajakan software. Oleh karena itu, rumusan masalah dalam penelitian ini yang di kaji adalah : a) Bagaimana bentuk perlindungan hak cipta dari tindakan pembajakan software ditinjau dari hukum internasional b) Bagaimana pengaturan perlindungan hukum hak cipta terhadap program komputer (software) menurut Undang-Undang Nomor 28 Tahun 2014 tentang Hak Cipta dan faktor apa saja yang menjadi hambatan dalam pelaksanaannya. Sedangkan metode penelitian menggunakan penelitian normative yaitu pendekatan penelitian ini berdasarkan bahan pustaka yang merupakan data sekunder atau disebut juga sebagai Penelitian Hukum Kepustakaan. Sedangkan analisa data dilakukan secara kualitatif.
Terminological Features of Studying the Language of Choreography (Based on Irish Dance Terms)
Authors: Rosyanova T. S. 
Published: November 2024

Introduction. The article examines issues related to the difficulties of describing poorly ordered terminologies. Domestic terminologists traditionally include choreography terminology among such types. This terminological area provides unique material for research, since it combines verbal specialized knowledge, as well as graphic illustrative explanatory support to clarify and record the body movements of performers. In connection with the development of the anthropocentric direction in linguistics, the study of the terminology of classical choreography, as well as the terms of folk dances, provides an opportunity to comprehend the technologies of art, in which the direct relationship of emotions, movement, strength of folk character, expression of freedom and the joy of being is manifested. Methodology and sources. Interest in the study of the terminology of humanitarian, economic and legal disciplines has become widespread in recent decades. The changed social context and social landscape have highlighted a huge layer of terminological vocabulary that was previously not in demand for large-scale terminology research.Methods of cognitive terminology allow us to consider not only systemic phenomena in terminology, categorization and conceptualization of special knowledge, but also key concepts that develop in synchrony and diachrony. The descriptive method and the method of definitional analysis are decisive for this work. The studied English terms of Irish folk dance were obtained by continuous sampling from original literature, terminological dictionaries and glossaries. Results and discussion. The uniqueness of the Irish folk dance terminology nomination lies, firstly, in the use of two languages: English and Gaelic. Secondly, the spread of the Irish diaspora across different continents creates the preconditions for the development of dance schools around the world and the consolidation of this bilingual terminology. In addition, organizing certification of teachers and holding festivals and competitions at the regional and world level contributes to the standardization of not only dances, but also terms. It seems that the publication of the best examples of dance heritage and recording them for posterity helped create the characteristic performing culture that we have seen in recent decades. Conclusion. The relevance of the work is due to the fact that the sphere of choreographic terminology in general and the terminology of Irish folk dances is an insufficiently studied area due to objective difficulties caused by the use of a combination of verbal and non-verbal resources to characterize dance movements. In addition, the study shows that the peculiarity of the terminological nomination, which, for historical reasons, preserves the balance of two languages, gives particular specificity to the contexts in which these terminological units operate.
The Concept of Cognitive Space in the Context of Cognitive Securitology
Authors: Plebanek O. V. 
Published: November 2024

Introduction. The article discusses the conceptual foundations of a new field of knowledge – cognitive securitology. The relevance of the study is due to the fact that the main means of cognitive warfare are modern digital technologies, while the object of influence of technical systems is mental systems, therefore there is a need to combine technical and humanitarian conceptual apparatus. The purpose of the article is to clarify the concept of “cognitive space” and distinguish between the concepts of information and cognitive spaces. Methodology and sources. One of the basic concepts of cognitive security is the concept of cognitive space, which has already been developed in linguistics, but due to the interdisciplinary nature of cognitive securitology needs to be clarified. Placing the category of cognitive space in the field of linguistic analysis narrows its content and does not make it possible to determine its semantic boundaries. The novelty of the analysis of the category “cognitive space” lies in the fact that the conceptual analysis of the category of cognitive space is based on the concept of self-organizing systems and the structural-functional approach. The concept of autopoiesis assumes that all elements and structures of the system, including cognitive ones, arise in order to ensure self-preservation, and the structural-functional approach allows us to determine the content and functions of the object. Results and discussion. Information space and cognitive space are intersecting but not coinciding fields, differing in their domains, but having one common task – ensuring the stability of the social system. Conclusion. The modern era is characterized by a global confrontation between civilizational systems and the transition of the confrontation into the phase of proxy wars, in which the main role is given to cognitive-psychological influence. Cognitive-psychological influence on the enemy is not only carried out at the preventive and preemptive stages of confrontation, but also often replaces other forms of war. Cognitive-psychological influence becomes possible and is carried out through the destruction of the cognitive space in which meanings and ideals that are specific to the social system function, which form goals and models of activity.
Aesthetics of Negative Communication: Conflicts of Journalists and Officials
Authors: Ogorodnova A. M. 
Published: November 2024

Introduction. The article proposes an aesthetic aspect of describing communication between journalists and politicians. The dramaturgical, image and consumer contexts of media communication, which, in our opinion, contain an aesthetic component, are problematized. An aesthetic look at the topic traditionally attributed to political science or sociological fields of knowledge allows us to see aspects of human activity that are perhaps less noticeable, but no less influential on the reproduction of the social order. Methodology and sources. The analysis of the situations discussed in the article is implemented in the tradition of interpretive sociology, which considers social communication as a constitutive factor in the behavior and activities of people. The principles of dramaturgical sociology of I. Hoffmann, theoretical observations of authors working in the field of symbolic politics, conceptual reasoning set out in F. Ankersmit’s essay “Political Representation” are used, in particular the term “representation” he uses in relation to the politician. Results and discussion. Situations that can be classified as negative communication between journalists and politicians were selected for analysis. The latter is defined as an action that can provoke negative emotions and feelings of communication participants, and thus disorient them regarding the development and consequences of the communicative situation. The obtained research results confirm that the concept of “negative communication” allows us to capture not only the emotional mode of professional activity and interprofessional communication of politicians and journalists, but also to offer an aesthetic view of professional communication. Conclusion. Situational analysis of conflicts in a professional environment, implemented in the tradition of interpretive sociology, reveals their spectacularity, predicting the forms of experience, and allows us to consider them, on the one hand, as works of art, on the other, as moral stories for social education. Aesthetic political representation is the most important need of any civil society, and its implementation is inextricably linked with political education.
Association between lactate/albumin ratio and 28-day mortality in ICU critical patients with coronary heart disease: a retrospective analysis of the MIMIC-IV database
Authors: Liu Ying 
Published: November 2024

BackgroundThe serum lactate/albumin ratio (LAR) is commonly employed for monitoring and evaluating the prognosis of critically ill patients. Both elevated lactate levels and decreased albumin levels may reflect the body's stress response and inflammatory reaction. Coronary heart disease (CHD), with common complications including myocardial infarction, arrhythmia, heart failure, is one of the leading causes of global death. Therefore, it is crucial to explore biomarkers that can predict the prognosis and mortality of CHD patients.MethodsThis is a retrospective study in which the data is from the MIMIC-IV database. Our study assessed the association between LAR value and mortality within 28 days of admission in a total of 1,902 CHD patients from the Beth Israel Deaconess Medical Center.ResultsThe results demonstrated a significant increase in 28-day mortality among individuals with higher LAR values. Multivariate analysis by Cox proportional hazard model revealed an incremental rise in mortality across each quartile with the increase of LAR value. Furthermore, restricted cubic spline (RCS) Cox regression analysis further revealed that higher LAR values were associated with increased 28-day mortality in the CHD patients. And subgroup analysis confirmed that the LAR level could serve as an independent predictor of 28-day mortality with CHD patients.ConclusionsOur study demonstrated that the LAR value can be an important risk predictor of 28-day mortality in patients with CHD, and a higher LAR associate with increased mortality rate.
Susceptibility assessment of geological hazards in Shenzhen Town, Ninghai county based on the APH-CF model
Authors: Han Shuai , Li Ran , Hui Shujun , Sun Qiang , Zhang Taili 
Published: November 2024

IntroductionThis work employs a coupled evaluation model that integrates deterministic coefficients with the Analytic Hierarchy Process to conduct a comprehensive assessment of geological disaster susceptibility in Shenzhen Town, Ninghai County.MethodsCascading geological disasters induced by typhoons and rainfall in the southeast coastal area of China are a major concern and cause huge losses of life and property every year. To effectively prevent and mitigate such disasters, it is necessary to evaluate the susceptibility of geological disasters. Taking geological disasters in Shenzhen Town, Ninghai County as the research object, eight influencing factors in terms of topographic and geomorphological conditions, engineering geological conditions, and human activities were selected based on the geographic information platform (GIS) in this work. The coupling model of the certainty factor model and analytic hierarchy process method was used to evaluate the susceptibility of geological hazards in the study area.ResultsThe evaluation results illustrate that the coupling model can accurately and objectively assess the susceptibility of geological hazards in this region, with a high evaluation accuracy of 80.8%. The susceptibility is greatly affected by slope, stratigraphic lithology, and human activities. The areas with extraordinarily high and high susceptibility were identified in the northwestern part of the study, where the ignimbrite is exposed in the steep topography.DiscussionThe research method provides a reference for evaluating the susceptibility of geological hazards in the southeastern coastal region of China, and the evaluation results can provide recommendations for decision-making on disaster prevention and mitigation in this region.
Maternal high fat diet exposure modifies amniotic fluid metabolites and expands group 3 innate lymphoid cells dependent on the maternal microbiome and MyD88-signaling
Authors: Niu Xinying , Lu Dongmei , Jaleel Sana , Palmer Suzette N. , Mahendroo Mala , Zhan Xiaowei , Mirpuri Julie 
Published: November 2024

BackgroundMaternal high fat diet (mHFD) exposure expands IL-17 producing group 3 innate lymphoid cells (IL17+ve ILC3) in the small intestine of neonatal murine offspring and increases their susceptibility to intestinal inflammation. How mHFD modulates innate immunity in the fetal offspring remains unclear.MethodsDams were exposed to 60% high fat diet or maintained on regular diet (RD) prior to and during mating. Amniotic fluid (AF) was collected during mid-pregnancy and metabolites examined by global non-targeted mass spectrometry in conventional wild-type (WT) and germ-free pregnant dams. Offspring were delivered by C-section or vaginally and fecal contents examined for major bacterial phyla and small intestinal lamina propria cells (LP) by flow cytometry. Susceptibility to intestinal inflammation was determined using a lipopolysaccharide and platelet-activating factor model (LPS/PAF) in WT, germ-free and MyD88 deficient offspring. Neonatal germ-free pups were exposed to HFD or RD AF by gavage and LP examined by flow cytometry.ResultsWe identified differentially produced metabolites in mHFD AF when compared to RD AF in conventionally raised mice, with no difference seen in germ-free mice. C-section delivery maintained the mHFD phenotype of expansion of IL17+ve ILC3 and increased susceptibility to inflammation in neonatal offspring. In addition, mHFD offspring had expansion of IL17+ve ILC3 at birth and 2 weeks of life, which was not seen in germ-free and MyD88 KO mice exposed to mHFD. Germ-free and MyD88 KO mice were protected from mHFD induced LPS/PAF injury and IL17+ve ILC3 expansion, demonstrating that the maternal microbiome and MyD88 are prenatally necessary for the expansion of IL17+ve ILC3 in mHFD offspring. Furthermore, introduction of mHFD AF to neonatal germ-free pups by gavage was sufficient to expand IL17+ve ILC3 in the small intestine.ConclusionOur findings indicate that mHFD interacts with the maternal microbiome to modify AF metabolites and signal via MyD88 to expand IL17+ve ILC3 in murine neonatal offspring.
The impact of a polyphenol-rich supplement on epigenetic and cellular markers of immune age: a pilot clinical study
Authors: Perlmutter Austin , Bland Jeffrey S. , Chandra Arti , Malani Sonia S. , Smith Ryan , Mendez Tavis L. , Dwaraka Varun B. 
Published: November 2024

Age-related alterations in immune function are believed to increase risk for a host of age-related diseases leading to premature death and disability. Programming of the immune system by diet, lifestyle, and environmental factors occurs across the lifespan and influences both makeup and function of the immune system, including immunometabolism. This programming is believed to act in large part through epigenetic modification. Among dietary components that affect this process, polyphenols may play an outsized role. Polyphenols are a widely distributed group of plant nutrients consumed by humans. Certain foods possess distinctive and relatively higher levels of these compounds. One such food is Tartary buckwheat (fagopyrum tataricum), an ancient seed historically prized for its health benefits. It is suggested that the specific composition of polyphenols found in foods like Tartary buckwheat may lead to a unique impact on immunometabolic physiological pathways that could be interrogated through epigenetic analyses. The objective of this study was to investigate the epigenetic effects on peripheral immune cells in healthy individuals of a standardized polyphenol concentrate based on naturally occurring nutrients in Tartary buckwheat. This pilot clinical trial tested the effects of consuming 90 days of this concentrate in 50 healthy male (40%) and female (60%) participants aged 18–85 years using epigenetic age clocks and deconvolution methods. Analysis revealed significant intervention-related changes in multiple epigenetic age clocks and immune markers as well as population-wide alterations in gene ontology (GO) pathways related to longevity and immunity. This study provides previously unidentified insights into the immune, longevity and epigenetic effects of consumption of polyphenol-rich plants and generates additional support for health interventions built around historically consumed plants like Tartary buckwheat while offering compelling opportunities for additional research.Clinical trial registrationClinicalTrials.gov, Identifier: NCT05234203.
Qingre Huoxue decoction attenuates myocardial ischemia‒reperfusion injury by regulating the autophagy‒endoplasmic reticulum stress axis via FAM134B-mediated ER-phagy
Authors: Li Rui , Zhang Jiechun , Ji Shuliang , Fang Junfeng , Ji Xiaodong , Zeng Yanping , Liu Nan , Wu Wei , Liu Shiyi 
Published: November 2024

BackgroundAutophagy‒endoplasmic reticulum (ER) stress axis dysregulation is linked to myocardial ischemia‒reperfusion injury (MIRI), which counteracts the benefits of acute myocardial infarction (AMI) reperfusion therapy. Qingre Huoxue decoction (QRHX) improves the short- and long-term prognosis of AMI after percutaneous coronary intervention and alleviates myocardial injury in AMI rats by stimulating autophagy via the PI3K/Akt pathway. We aimed to further explore the efficacy of QRHX in treating MIRI and its regulatory relationship with FAM134B-mediated ER-phagy.Materials and methodsRats were administered different concentrations of QRHX for 2 weeks, and then MIRI was induced. Ultra-performance liquid chromatography‒tandem mass spectrometry (UPLC‒MS) was used to examine the levels of the main pharmacological metabolites of the serum of rats treated with QRHX. H9c2 cells were pretreated with QRHX-mediating serum (QRHX-MS) for 24 h before being exposed to hypoxia/reoxygenation (H/R). The mechanisms underlying the effects of QRHX-MS were further studied via rescue experiments involving FAM134B knockdown. The myocardial infarct size, cardiac function, morphology and the expression of apoptosis-, autophagy-, and ER stress-related proteins and genes were assessed. The colocalization of autophagosomes with lysosomes and the localization of proteins involved in ER-phagy or autophagic flux was examined.ResultsQRHX decreased the myocardial infarct size and oxidative stress, improved cardiac function and alleviated morphological changes in a dose-dependent manner in MIRI rats by promoting autophagic flux to inhibit ER stress and ER stress-related apoptosis, which was related to FAM134B-mediated ER-phagy, as revealed by autophagy analysis. UPLC‒MS analysis of QRHX-MS revealed 20 major active metabolites of QRHX-MS, including baicalin, cryptotanshinone, 3,4-dihydroxybenzaldehyde and caffeic acid. QRHX-MS attenuated H/R-induced cardiomyocyte injury and apoptosis by increasing autophagic flux to suppress ER stress and ER stress-related apoptotic protein and gene expression. When autophagic flux was inhibited or FAM134B was knocked down in H9c2 cells followed by QRHX-MS pretreatment, the protective effect of QRHX was partially reversed.ConclusionQRHX alleviates myocardial injury, apoptosis and infarct size expansion in MIRI by regulating the autophagy‒ER stress axis via FAM134B-mediated ER-phagy.
Sea food by-products valorization for biomedical applications: evaluation of their wound regeneration capabilities in an Ex vivo skin model
Authors: Zivelonghi Giulia , Melotti Luca , Carolo Anna , Venerando Andrea , Roncoroni Margherita , Martinelli Giordana , Maccatrozzo Lisa , Marzorati Stefania , Sugni Michela , Patruno Marco 
Published: November 2024

IntroductionThe skin is often exposed to harmful stimuli that might compromise its integrity and functionality. After an injury, the skin has a limited capability to restore its complex structure, and in the case of severe skin damage, surgical operations and rapid application of wound dressings are often required to promote optimal wound healing. Nowadays, collagen-based biomaterials are widely used in combination with bioactive molecules able to prevent excessive inflammation and possible infections. In line with a circular economy and blue biotechnology approach, it was recently demonstrated that both collagen and bioactive molecules (i.e., antioxidant compounds) can be sustainably obtained from sea food by-products and effectively used for biomaterial development. Herein, we describe and compare the application of two marine collagen-based wound dressings (CBWDs), produced with materials obtained from sea urchin food waste, for the treatment of skin lesions in a wound healing organ culture (WHOC) model.MethodsThe ex vivo WHOC model was set up starting from rat skin explants and the induced lesions were assigned into three different groups: control (CTRL) group, not treated, marine collagen wound dressing (MCWD) group, and antioxidants-enriched marine collagen wound dressing (A-MCWD) group. After 5 and 10 days, specimens were examined for organ maintenance and assessed for the healing process.ResultsImmunohistochemical results showed that both CBWDs were similarly successful in prolonging skin repair, preserving the epidermal barrier up to 5 days under static culture conditions. Histological and gene expression analysis highlighted that the A-MCWD might support and accelerate skin wound healing by exerting antioxidant activity and counteracting inflammation.DiscussionOverall, these findings underline the potential of sea urchin food waste as a novel resource for the development of functional medical devices for the treatment of skin wounds.