bluuebunny/crossref_metadata_2025_split huggingface dataset:
Le ton de Patrick Modiano : du roman ironique au roman affectif
Authors: Amar Ruth 
Published: June 2019

Cette étude analyse la manière dont s’exprime le ton de Modiano, la manière par laquelle l’auteur s’individualise. Un ton difficile à saisir, car s’il paraît au premier abord neutre, derrière les phrases, se cachent des éléments qui contribuent à un ton spécifique,voire à la voix de l’auteur. Au fil de l’œuvre, l’on découvre que la voix de Modiano n’est pas homogène. Le ton du jeune écrivain des années 1970 n’est pas celui des années 1980. Il s’est métamorphosé et a évolué de manière considérable. En comparant La Place de l’étoile et Dora Bruder, on est conscient de la transformation : le ton retentissant des débuts de Modiano s’est affaiblit, devenant presque imperceptible, reflétant le fait que la représentation de l’holocauste dans ces deux livres est bien différente. Abstract In this paper I will explore the way in which the characteristics of Modiano’s tone are expressed in the texts, the way in which the author individualizes himself. A tone so hard to cease as it seems at first neutral, but behind the sentences, are hidden elements that contribute to the specific tone and even to the voice of the writer. In considering the work, one finds that the voice of Modiano is not homogeneous. The tone of young writer of the seventies is no longer that of the writer of the nineties. He has suffered metamorphosis and has evolved significantly. In comparing La Place de l’étoile to Dora Bruder, one becomes well aware of the transformation: the tone first shining and thundering, is weakened to become, almost imperceptible and reflects the fact that the representation of the Holocaust in these two books is quite different.
Eustachian tube functional assessment among patients with CSOM undergoing tympanoplasty surgery
Authors: P. Hemalatha , V. J. Vikram 
Published: June 2019

<p class="abstract"><strong>Background:</strong> Pre-operative test of eustachian tube (ET) function is important for achieving a satisfactory result of tympanoplasty for CSOM patients. The saccharin test and methylene blue test seems to provide adequate information of the mucociliary function and patency of the ET. The aim was to study the ventilatory and mucociliary function of Eustachian tube in patients with chronic suppurative otitis media planned for tympanoplasty surgery and to assess the success rate of tympanoplasty in relation to the Eustachian tube function</p><p class="abstract"><strong>Methods:</strong> A prospective longitudinal study was conducted for a period of one year. Patients aged more than 15 years with features of chronic suppurative otitis media of either tubotympanic type or atticoantral type were included in the study. The total number of study subjects included in our study was 82 patients with CSOM. The ventilatory and the mucociliary functions of the auditory tube were assessed preoperatively using saccharin test and methylene blue test. All patients with CSOM underwent tympanoplasty surgery and the outcome of the surgery was assessed. </p><p class="abstract"><strong>Results:</strong> The overall success rate of tympanoplasty surgery was 76.8%. It was observed in our study that the success rate of tympanoplasty was higher among patients with normal eustachian tube function.</p><p class="abstract"><strong>Conclusions:</strong> Preoperative evaluation of eustachian tube function is mandatory for all the patients planned for tympanoplasty. Preoperative and intraoperative corrective measures should be taken in patients with partial and absent tubal function to improve the success rate of tympanoplasty surgeries.</p><p> </p>
De ontwikkeling van de nationalistische beweging in Nederlands-Indië
Authors: Locher-Scholten E.B. 
Published: June 2019

R.C. Kwantes, De ontwikkeling van de nationalistische beweging in Nederlandsch-Indië. Bronnenpublicatie, Tweede stuk, Medio 1923-1928 R.C. Kwantes, De ontwikkeling van de nationalistische beweging in Nederlandsch-Indië. Bronnenpublicatie, Derde stuk, 1928-augustus 1933 R.C. Kwantes, De ontwikkeling van de nationalistische beweging in Nederlandsch-Indië. Bronnenpublicatie, Vierde stuk, augustus 1933-1942
Willem van Oranje 1584-1984. Een literatuuroverzicht
Authors: Postma F.R. 
Published: June 2019

R.H. Bremmer, Reformatie en rebellie. Willem van Oranje, de calvinisten en het recht van opstand. Tien ontstuimige jaren: 1572-1581 A.Th. van Deursen, Willem van Oranje. Een strijd voor vrijheid en verdraagzaamheid E.O.G. Haitsma Mulier, A.E.M. Jansen, Willem van Oranje in de historie. Vier eeuwen beeldvorming en geschiedschrijving J.H. Kluiver, De correspondentie tussen Willem van Oranje en Jan van Nassau, 1578-1584 F. Wieringa, Republiek tussen Vorsten. Oranje, Opstand, Vrijheid, Geloof
Mechanical complications of acute myocardial infarction considering risk factors, treatment and survival of patients in 10-year clinical observation
Authors: Dąbek Józefa , Skorus Paweł , Potyka Katarzyna , Potyka Marek , Stachoń Krystian , Gąsior Zbigniew 
Published: June 2019

WstępChoroby układu krążenia, w tym choroba wieńcowa i jej powikłania, stanowią najczęstszą przyczynę zgonów.
Zawał mięśnia sercowego spowodowany jest zwykle pęknięciem blaszki miażdżycowej i zamknięciem tętnicy wieńcowej
skrzepliną.Materiał i metodyBadaniem objęto 52 chorych (100%) z mechanicznymi powikłaniami ostrego zawału serca, hospitalizowanych
w II Oddziale Kardiologii oraz Oddziale Anestezjologii i Intensywnej Terapii Górnośląskiego Centrum Medycznego w Katowicach w latach 2006–2016, w tym 23 kobiety (44,2%) i 29 mężczyzn (55,8%) w wieku 54‒84 lat (średnia wieku 69,8 roku).WynikiNajczęstszym powikłaniem było pęknięcie przegrody międzykomorowej (n = 36; 69,2%), natomiast do najrzadszych
należały pęknięcie mięśnia brodawkowatego (n = 4; 7,7%) i pęknięcie ścięgien (n = 4; 7,7%). Nadciśnienie i hipercholesterolemia były najczęstszymi czynnikami ryzyka wystąpienia choroby niedokrwiennej serca w badanej grupie.
Zwiększoną śmiertelność zaobserwowano u pacjentów leczonych farmakologicznie (87,5%), podczas gdy śmiertelność pacjentów leczonych operacyjnie wynosiła 61,4%. U większości pacjentów występował jeden czynnik ryzyka choroby wieńcowej (n = 28; 53,8%).Wnioski1. Najczęstszymi powikłaniami były pęknięcie przegrody międzykomorowej i pęknięcie ściany serca.
2. U pacjentów występowało wiele czynników ryzyka dla choroby niedokrwiennej serca, spośród których najczęstszymi
były nadciśnienie i hipercholesterolemia.
3. Śmiertelność w badanej grupie chorych z mechanicznymi powikłaniami ostrego zawału serca znacznie przewyższała
przeżywalność i była większa w grupie leczonych zachowawczo.
MIDWIVES’ COMPLIANCE TO THE STANDARD OPERATING PROCEDURE ON THE EARLY IDENTIFICATION OF PREECLAMPSIA
Authors: Islami Dian 
Published: June 2019

Background: The main cause of maternal mortality in East Java was pregnancy hypertension (Preeclampsia/eclampsia). The percentages of pregnant women treated with early identification of preeclampsia care according to Standard Operating Procedure (SOP) in primary healthcare centers of Surabaya was still low (26%).Aim: This study aimed to analyze the factors that influence midwives’ compliance towards the SOP implementation of early identification of preeclampsia in primary healthcare centers of Surabaya.Methods: The study was an observational analytic research with cross sectional. The samples chose midwives at 20 primary healthcare centers as the informants. The independent variables are individual factors, organizational factors, and psychological factors of the midwives. The dependent variable was midwives’ compliance towards the implementation of SOP for early identification of preeclampsia.Results: The results of this study show 35% of primary healthcare centers have not implemented the SOP of early identification of Preeclampsia in pregnant women. The results also showed that the majority of primary healthcare centers in Surabaya had midwives aged 31 to 40 years (50%), graduated from a Diploma 3 education (95%), contracted status (85%) and still worked less than six years (60%).Conclusion: This research highlighted the midwives’ compliance which was determined not only by individual internal factors, but also organizational behavior. Preparing early identification of preeclampsia mechanisms, facility, and equipment proposal is important to do with the implementation of supportive system, quality control team, reward as well as punishment system. Keywords: Compliance, Early identification, Midwives, Preeclampsia, SOP.
Enhanced recovery after surgery (ERAS) pathway for primary hip and knee arthroplasty: study protocol for a randomized controlled trial
Authors: Li Jingyi , Zhu Haibei , Liao Ren 
Published: June 2019

Abstract
Background: With the substantially growing trend of the aging populations in China and the rest of the world, the number of total hip and total knee arthroplasty (THA and TKA) cases are increasing dramatically. It’s important to develop practical strategies to improve the quality of healthcare and better outcome for patients undergoing THA and TKA. Enhanced recovery after surgery (ERAS) pathways have been reported to promote earlier recovery and be beneficial for patients. We propose the hypothesis that ERAS pathway could provide better recovery for patients undergoing primary THA or TKA.
Methods/Design: This trial is a prospective, open-labelled, randomized controlled trial that will evaluate the length of stay (LOS) in hospital, and other end points of interest for the patients undergoing ERAS pathway as compared to current non-ERAS clinical practice. A total of 640 patients undergoing primary THA or TKA will be randomly allocated to either ERAS pathway (ERAS group) or conventional care according to individual participating center (non-ERAS group). The primary outcome is the total LOS in hospital, the secondary outcomes include Postoperative LOS, all-cause mortality by 30 days after operation, in-hospital complications, early mobilization, postoperative pain control, total in-hospital cost, and readmission rate by 30 days after discharge from the hospital.
Discussion: This trial is designed to evaluate the superiority of the ERAS pathway to conventional non-ERAS clinical practice in reducing the LOS without increasing the incidence of complications or medical cost. The results will provide new insight into the clinical applications of ERAS pathway for total hip and total knee arthroplasty.
Trial registration: The National Institutes of Health Clinical Trials Registry, NCT03517098. Registered 04, May, 2018. https://register.clinicaltrials.gov/prs/app/action/ SelectProtocol?sid=S0007YV7&selectaction=Edit&uid=U0001B4E&ts=2&cx=97eyz9
Randomised controlled trial on vitreoretinal surgery with and without oral anticoagulants: surgical complications, visual results and perioperative thromboembolic events
Authors: Andonegui Jose , Capdevila Ferran , Zubicoa Alicia , Ibáñez Berta 
Published: June 2019

Abstract
Background Vitreoretinal surgery in anticoagulated patients is a challenging situation for vitreoretinal surgeons, who have to choose between being faced with the systemic thromboembolic risks that the interruption of anticoagulation involves, or the intra and postoperative haemorrhagic risks associated with maintenance of this therapy. So far, no trial has compared, in a prospective and randomized manner, perioperative complications and the visual results associated with continuation or interruption of oral anticoagulant therapy before pars plana vitrectomy under retrobulbar anaesthesia. The main objective of this trial is to compare haemostasis-related perioperative complications of PPV in patients maintaining anticoagulant therapy before surgery compared to patients who interrupt this therapy before surgery. Methods Ninety six patients will be randomly assigned to either the control group, to whom oral anticoagulant therapy will be interrupted and substituted with subcutaneous heparin according to local clinical practice, or the intervention group to whom oral anticoagulant therapy will not be interrupted before surgery. Patients will be stratified according to the oral anticoagulant they were taking (direct or indirect anticoagulation). They will be followed-up for 12 weeks, and the primary outcome, and haemorrhagic complications until 15 days after surgery, will be evaluated. Discusion This trial will provide novel information on the possibility of continuing anticoagulant therapy during PPV. The benefits expected from the change in the current surgical management paradigm for anticoagulated patients would be a decreased risk in the incidence of perioperative thromboembolic events and the possibility of performing surgery without delay and without the need for patients to change their usual anticoagulation protocol to the more complex and less safe substitutive therapy.
Efficacy of integrating vestibular rehabilitation and cognitive behaviour therapy in persons with long-term dizziness in primary care– a study protocol for a randomised controlled trial
Authors: Kristiansen Lene , Magnussen Liv Heide , Wilhelmsen Kjersti Thulin , Mæland Silje , Nordahl Stein-Helge Glad , Clendaniel Richard , Hovland Anders , Juul-Kristensen Birgit 
Published: June 2019

Abstract
Background: Dizziness is a common complaint, and the symptom often persists, together with additional complaints. A treatment combining of Vestibular Rehabilitation (VR) and Cognitive Behaviour Therapy (CBT) is suggested. However, further research is necessary to evaluate the efficacy of such intervention. The objective of this paper is to present the design of a randomised controlled trial aiming at evaluating the efficacy of an integrated treatment of VR and CBT on dizziness, physical function, psychological complaints and quality of life in persons with persistent dizziness. Methods/Design: The randomised controlled trial is an assessor-blinded block randomised parallel-group design, with a 6- and 12- month follow-up. The study includes 125 participants from Bergen (Norway) and surrounding areas. Included participants present with persistent dizziness lasting at least 3 months, triggered or exacerbated by movement. All participants receive a one-session treatment (Brief Intervention) with VR before being randomised into a control-group or an intervention-group. The intervention-group will further be offered an eight-session treatment integrating VR and CBT. The primary outcomes in the study are the dizziness handicap inventory and preferred gait velocity. Discussion: Previous studies combining these treatments have been of varying methodological quality, with small samples, and long-term effects have not been maintained. In addition, only the CBT has been administered in supervised sessions, with VR offered as home-exercises. The current study focuses on the integrated treatment, sufficiently powered sample size, and a standardised treatment program evaluated by validated outcomes using a standardised assessment protocol. Trial registration: The study was registered at www.clinicaltrials.gov (NCT02655575) on January 14th 2016.
Assessing Quality Improvement Capacity in Primary Care Practices
Authors: Parchman Michael , Anderson Melissa L. , Coleman Katie F , Michaels LeAnn , Schuttner Linnaea , Conway Cullen , Hsu Clarissa , Fagnan Lyle J. 
Published: June 2019

Abstract
Background

Healthy Hearts Northwest (H2N) is a study of external support strategies to build quality improvement (QI) capacity in primary care with a focus on cardiovascular risk factors: appropriate aspirin use, blood pressure control, and tobacco screening/cessation.

Methods

To guide practice facilitator support, experts in practice transformation identified seven domains of QI capacity and mapped items from a previously validated medical home assessment tool to them. A practice facilitator (PF) met with clinicians and staff in each practice to discuss each item on the Quality Improvement Capacity Assessment (QICA) resulting in a practice-level response to each item. We examined the association between the QICA total and sub-scale scores, practice characteristics, a measure of prior experience with managing practice change, and performance on clinical quality measures (CQMs) for the three cardiovascular risk factors. Field notes kept by the PFs from practices with high and low QICA scores were compared.

Results

The QICA score was associated with prior experience managing change and two of the three CQMs: aspirin use (r=0.16, p=0.049) and blood pressure control (r=0.18, p=0.013). Rural practices and those with 2-5 clinicians had lower QICA scores. PFs notes provide examples of high scoring practices devoting time and attention to quality improvement whereas low scoring practices did not.

Conclusions

The QICA is useful for both assessing QI capacity within a practice and for guiding PFs and practices in efforts to build this capacity. Further work is needed to understand how PFs and practices tailored their work in response to this practice-level assessment and how practices used it to improve their QI capacity.
An unusual Neuronal Intranuclear Inclusion Disease with Chief Complaint of Autonomic Dysfunction
Authors: Liu Xiaoyun , Liu Xiaohui , Du Yifeng , Li Chunxia , liu Cuicui , Lu Lin 
Published: June 2019

Abstract
Background

Neuronal intranuclear inclusion disease (NIID) is a recently defined disease entity of progressive neurodegenerative disease with characterizations of eosinophilic hyaline intranuclear inclusions in neuronal and somatic cells. The sporadic adult-onset NIID cases were previous described as ‘dementia dominant group’. Here we present a NIID case manifested prominently with recurrent vomiting.

Case presentation

A 60-year-old women present with paroxysmal vomiting, hypertention and decreased level of consciousness for 3 years. She was diagnosed with NIID based on history, clinical features, brain magnetic resonance imaging(MRI), skin biopsy.

Conclusion

Autonomic symptoms may manifest as the initial and predominant presentation of NIID. This case presentation may extend the spectrum of NIID and may give new insights in exploring the pathogenic mechanisms of NIID.
High-intensity exercise to promote accelerated improvements in cardiorespiratory fitness (HI-PACE): Study protocol for a randomized controlled trial
Authors: McGee Joshua E. , Barefoot Savanna G. , Gniewek Nicole R. , Brophy Patricia M. , Clark Angela , Dubis Gabriel S. , Ryan Terence E. , Houmard Joseph A. , Vos Paul , Raedeke Thomas D. , Swift Damon L. 
Published: June 2019

Abstract
Background

African Americans have a disproportionate prevalence and incidence of type 2 diabetes compared to Caucasians. Recent evidence indicates low cardiorespiratory fitness (CRF) level, an independent risk factor for type 2 diabetes, is also more prevalent in African Americans than Caucasians. Numerous studies in Caucasian populations suggest vigorous exercise intensity may promote greater improvements in CRF and other type 2 diabetes risk factors (e.g. reduction of glucose/insulin levels, pulse wave velocity, body fat, etc.) than moderate intensity. However, current evidence comparing health benefits of different aerobic exercise intensities on type 2 diabetes risk factors in African Americans is negligible. This is clinically important as African Americans have a greater risk for type 2 diabetes and are less likely to meet public health recommendations for physical activity than Caucasians. The purpose of the High-Intensity exercise to Promote Accelerated improvements in CardiorEspiratory fitness (HI-PACE) study is to evaluate whether high-intensity aerobic exercise elicits greater improvements in CRF, insulin action, and arterial stiffness than moderate-intensity exercise in African Americans.

Methods/Design­

A randomized controlled trial will be performed on overweight and obese (body mass index: 25-45 kg/m2) African Americans (35-65 years) (n=60). Participants will be randomized to moderate-intensity (MOD-INT) or high-intensity (HIGH-INT) aerobic exercise training, or a non-exercise control group (CON) for 24 weeks. Supervised exercise will be performed at a heart rate associated with 45-55% and 70-80% of VO2 max in the MOD-INT and the HIGH-INT groups, respectively, for an exercise dose of 600 MET-minutes/week (consistent with public health recommendations). The primary outcome is change in CRF. Secondary outcomes include change in insulin sensitivity (measured via an intravenous glucose tolerance test), skeletal muscle mitochondrial oxidative capacity (via near infrared spectroscopy), skeletal muscle measurements (i.e. citrate synthase, COX IV, GLUT-4, CPT-1, PGC1-α), arterial stiffness (via carotid-femoral pulse wave velocity), body fat, C-reactive protein, and psychological outcomes (quality of life/exercise enjoyment).

Discussion

The anticipated results of the HI-PACE study will provide vital information on the health effects of high-intensity exercise in African Americans. This study will advance health disparity research and has the potential to influence future public health guidelines for physical activity.
Comparison of subfoveal choroidal thickness in eyes with CRVO and BRVO
Authors: Author) Fen Tang(Former Corresponding , Xu Fan , Zhong Haibin , Zhao Xin , Lv Mingliang , Yang Ke , Shen Chaolan , Huang Hui , Lv Jian , Zeng Siming , Author) Min Li(New Corresponding , Chen Qi 
Published: June 2019

Abstract
Backgroud: To evaluate the subfoveal choroidal thickness (SFCT) in eyes with macular edema (ME) secondary to retinal vein occlusion（RVO），and to investigate the short term response after a single intravitreal ranibizumab (IVR) injection. What is more, to compare SFCT and SFCT change between central RVO (CRVO) and branch RVO (BRVO).
Methods: In the retrospective study, we had collected thirty-six treatment-naïve patients with unilateral ME secondary to RVO (including nineteen CRVO and seventeen BRVO). All patients had received IVR injection after newly diagnosed. The SFCT was measured at the onset and after two weeks of IVR injection. Paired t test was performed to compare the SFCT of RVO eyes and fellow eyes, as well as the SFCT of pre-injection and post-injection. In further, independent t test was used to compare SFCT and SFCT change between CRVO eyes and BRVO eyes.
Results: The mean SFCT at the onset was 326.03±30.86 μm in CRVO eyes, which was significantly thicker than that in contralateral fellow eyes (p<0.01, paired t test), and reduced to 294.15±30.83 μm rapidly after two weeks of IVR injection (p<0.01, paired t test). Similarly, the SFCT in BRVO eyes was significantly thicker than that in contralateral eyes at the onset, and decreased significantly after IVR injection. However, our findings showed that there was no statistically significant difference in SFCT and SFCT reduction after IVR injection between CRVO eyes and BRVO eyes.
Conclusions: The SFCT in eyes with ME secondary to CRVO and BRVO was significantly thicker than that in fellow eyes, and decreased significantly within a short time in response to a single IVR injection. In further, the study showed that SFCT and SFCT change had no correlation with RVO subtypes.