bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Horizontal Divergence in Submesoscale Frontogenesis
Authors: Barkan Roy , Molemaker M. Jeroen , Srinivasan Kaushik , McWilliams James C. , D’Asaro Eric A. 
Published: April 2019

AbstractOceanic surface submesoscale currents are characterized by anisotropic fronts and filaments with widths from 100 m to a few kilometers; an O(1) Rossby number; and large magnitudes of lateral buoyancy and velocity gradients, cyclonic vorticity, and convergence. We derive an asymptotic model of submeoscale frontogenesis—the rate of sharpening of submesoscale gradients—and show that in contrast with “classical” deformation frontogenesis, the near-surface convergent motions, which are associated with the ageostrophic secondary circulation, determine the gradient sharpening rates. Analytical solutions for the inviscid Lagrangian evolution of the gradient fields in the proposed asymptotic regime are provided, and emphasize the importance of ageostrophic motions in governing frontal evolution. These analytical solutions are further used to derive a scaling relation for the vertical buoyancy fluxes that accompany the gradient sharpening process. Realistic numerical simulations and drifter observations in the northern Gulf of Mexico during winter confirm the applicability of the asymptotic model to strong frontogenesis. Careful analysis of the numerical simulations and field measurements demonstrates that a subtle balance between boundary layer turbulence, pressure, and Coriolis effects (e.g., turbulent thermal wind; Gula et al. 2014) leads to the generation of the surface convergent motions that drive frontogenesis in this region. Because the asymptotic model makes no assumptions about the physical mechanisms that initiate the convergent frontogenetic motions, it is generic for submesoscale frontogenesis of O(1) Rossby number flows.
Resonance Scattering Detection Using the CSU–CHILL Dual-Wavelength, Dual-Polarization Radar
Authors: Junyent Francesc , Chandrasekar V. , Kennedy P. 
Published: April 2019

AbstractThe CSU–CHILL radar is a dual-wavelength, dual-polarization weather radar system operating at S and X band with coaxial beams. This radar system offers a unique environment to develop and/or validate algorithms that cut across its wavelengths and polarizations. This paper presents a method to retrieve resonance scattering regions from the difference in intrinsic reflectivities after attenuation correction, which is performed using measured reflectivity fields only. The algorithm to retrieve these regions dominated by non-Rayleigh scattering is applied to different storm events, and the obtained data field capturing the difference in S- and X-band reflectivities due to resonance effects (which we will call Mie signal for convenience) is compared to the collocated dual-polarization fields. The obtained Mie signal is also compared to hail reports. In both cases, the retrieved Mie signal is found to be consistent with the rest of the dual-polarization data fields, and in some situations, it is shown to bring information not directly discernible from the usual dual-polarization radar variables.
A New Radar Scan Mode to Increase Clear-Air Velocity Data Coverage and Usability for Wind Analysis
Authors: Xu Qin , Nai Kang , Melnikov Valery 
Published: April 2019

AbstractBy using long pulses with extended dwell time, radar sensitivity is enhanced such that more clear-air returns are usable. This enhanced capability can increase clear-air data coverage and provide additional information for radar wind analysis and data assimilation. To explore this potential capability and related benefits, a new scan mode with long pulses and low antenna rotation rate is derived from the existing clear-air scan mode and applied to the named KOUN S-band test bed radar at NSSL. Velocities collected using this newly modified scan mode are significantly enhanced in data coverage compared to those collected with the unmodified scan mode from the nearby test bed radar (named KCRI). However, transmitter duty cycle limits the pulse repetition frequency (PRF) to 455 Hz for the long pulses, which reduces the Nyquist velocity to 12.53 m s−1 for the new scan mode. Such a small Nyquist interval leads to significantly worse problems with aliased velocities. A recently developed dealiasing algorithm is modified by using external reference velocities from KCRI to overcome increased difficulties in dealiasing, making the velocities from KOUN useful over increased range and area. This implies that similar increases in velocity data coverage can be achieved without using external reference velocities if the newly modified scan is paired with an unmodified scan into dual-PRF scans. This dual-PRF approach is proposed for future development.
Decomposition of the Multimodal Multidirectional M2 Internal Tide Field
Authors: Zhao Zhongxiang , Wang Jinbo , Menemenlis Dimitris , Fu Lee-Lueng , Chen Shuiming , Qiu Bo 
Published: April 2019

AbstractThe M2 internal tide field contains waves of various baroclinic modes and various horizontal propagation directions. This paper presents a technique for decomposing the sea surface height (SSH) field of the multimodal multidirectional internal tide. The technique consists of two steps: first, different baroclinic modes are decomposed by two-dimensional (2D) spatial filtering, utilizing their different horizontal wavelengths; second, multidirectional waves in each mode are decomposed by 2D plane wave analysis. The decomposition technique is demonstrated using the M2 internal tide field simulated by the MITgcm. This paper focuses on a region lying off the U.S. West Coast ranging 20°–50°N, 220°–245°E. The lowest three baroclinic modes are separately resolved from the internal tide field; each mode is further decomposed into five waves of arbitrary propagation directions in the horizontal. The decomposed fields yield unprecedented details on the internal tide’s generation and propagation, which cannot be observed in the harmonically fitted field. The results reveal that the mode-1 M2 internal tide in the study region is dominantly from the Hawaiian Ridge to the west but also generated locally at the Mendocino Ridge and continental slope. The mode-2 and mode-3 M2 internal tides are generated at isolated seamounts, as well as at the Mendocino Ridge and continental slope. The Mendocino Ridge radiates both southbound and northbound M2 internal tides for all three modes. Their propagation distances decrease with increasing mode number: mode-1 waves can travel over 2000 km, while mode-3 waves can only be tracked for 300 km. The decomposition technique may be extended to other tidal constituents and to the global ocean.
Long-Term Voice and Swallowing Outcomes for Oral and Oropharyngeal Cancer Following Primary or Adjuvant Chemoradiation
Authors: Soldatova Liuba , Mirza Natasha 
Published: April 2019

Objective: Chemoradiation (CRT) for nonlaryngeal head and neck cancer (HNC) can lead to voice and swallowing dysfunction. The purpose of this study was to examine voice and swallowing from the patient’s perspective at least 5 years after treatment. Design: Patient survey. Methods: Twenty-eight patients treated with primary or adjuvant CRT at least 5 years ago (mean = 10.7 years, SD = 5.5, range, 5-28) completed a survey created based on previously validated questionnaires (the Patient Perception of Swallowing Function Questionnaire, PPSFQ; the Eating Assessment Tool, EAT-10; the Voice Handicap Index, VHI-10; the Voice Related Quality of Life, V-RQOL). Results: Patients reported some voice and swallowing dysfunction (39% of V-RQOL scores in categories of fair, poor, or worst possible and 32% of VHI-10 scores ≥20 or greater than 50% of the maximum; 39% of PPSFQ scores greater than 50% of the maximum and 32% of EAT-10 scores ≥20 or 50% of the maximum). There was a correlation between V-RQOL and VHI-10 scores (Pearson product moment correlation coefficient r = .96, calculated probability value p = 0), PPSFQ and EAT-10 scores (r = 0.87, p = 0.8 × 10−8), as well as between V-RQOL and PPSFQ/EAT-10 scores (r = .94, p = 0), VHI-10 and PPSFQ/EAT-10 scores (r = .97, p = 0). Conclusions: Perceived voice and swallowing dysfunction following CRT for nonlaryngeal HNC can persist or worsen beyond 5 years.
Physiological Factors Which Influence Cognitive Performance in Military Personnel
Authors: Martin Kristy , Périard Julien , Rattray Ben , Pyne David B. 
Published: April 2019

Objective: To identify and detail physiological factors that influence cognition in military personnel. Background: Maintenance of cognitive and task performance is important under several scenarios, none more so than in a military context. Personnel are prepared for and trained to tolerate many of the stressors they encounter; however, consideration of stressors typically extends only as far as the physical, psychological, and environmental requirements of a given task. While considering these factors certainly characterizes the broader picture, several physiological states and traits can influence cognition and thus, should also be considered. Method: A systematic review of the electronic databases Medline (PubMed), EMBASE (Scopus), PsycINFO, and Web of Science was conducted from inception up to January 2019. Eligibility criteria included current military personnel, an outcome of cognition, and the assessment of a physiological factor. Results: The search returned 60,564 records, of which 60 were included in the review. Eleven studies examined the impact of demographic factors on cognition, 16 examined fatigue, 10 investigated nutrition, and 24 the impact of biological factors on cognitive performance. Conclusion: Factors identified as having a positive impact on cognition include aerobic fitness, nutritional supplementation, and visual acuity. In contrast, factors identified as having a negative impact include fatigue arising from sustained operations, dehydration, undernutrition, and an exaggerated physiological stress response to a cognitive task or a stressor. A further subset of these factors was considered modifiable. Application: The modifiable factors identified provide avenues for training and preparation to enhance cognition in ways previously unconsidered.
Human Embryonic Stem Cell Research, Abortion, and Publication Bias in the New England Journal of Medicine
Authors: Baumgartner Fritz 
Published: April 2019

Publication bias in medical journals depends on outside influences and the particular ideological bent of the editorial board. The New England Journal of Medicine ( NEJM) is a premier medical scientific publication having among the highest impact rankings of any research journal. The Vioxx question and industry ties it highlighted have led to legitimate questions of whether significant conflicts of interest have arisen within NEJM that compromise the free exchange of scientific information and ideas. Over the past two decades, several socially charged areas have been treated with considerable bias in the editorial policy of NEJM, including the issues of human embryonic stem cell research and abortion. From 2000 to 2017, NEJM published over twenty pieces favorable toward human embryonic stem cell research and over fifty pieces favorable to abortion, with virtually no publication of contrary opinion. An aggressive editorial defense of Planned Parenthood Federation most recently seems particularly striking. A secular journal which is meant to represent the entire spectrum of physician opinion in controversial issues has a practical, if not also an ethical, responsibility to provide an unbiased forum for intelligible discussion for evaluation of the merits of particular issues. To do otherwise is publication bias that suppresses legitimate contrary viewpoints having merit and validity. Nontechnical Summary: Publication bias in medical journals is detrimental to the free exchange of ideas regarding controversial issues. From 2000 to 2017, a premier publication, the New England Journal of Medicine ( NEJM), has shown considerable bias in only publishing articles and editorials highly favorable toward human embryonic stem cell research and abortion, without permitting valid discussion and publication of contrary opinion. The recent strong editorial defense by NEJM of Planned Parenthood Federation in their sale of aborted fetal body parts seems particularly striking and disproportionate. Publication bias suppresses legitimate contrary viewpoints with merit and validity, suppressing fair debate in controversial issues.
Grandparent Caregivers’ Resilience: Stress, Support, and Coping Predict Life Satisfaction
Authors: Mendoza Angela N. , Fruhauf Christine A. , MacPhee David 
Published: April 2019

Objectives Do support and coping strategies moderate the link between stress and life satisfaction among grandparent caregivers? Background Grandparents raising grandchildren often experience stress, which may compromise their subjective well-being. Thus, it is important to understand the role of support and coping as protective or promotive factors in relation to grandparent caregivers’ resilience (i.e., life satisfaction). Methods Grandparent caregivers ( N = 74) reported their daily hassles, life satisfaction, social support, and coping. Results These grandparent caregivers are a vulnerable population in terms of stress and limited social support and coping. Structural equation modeling supported direct, promotive effects of social support and coping on life satisfaction, but not moderation. Conclusion Despite high levels of stress, half of the grandparent caregivers were satisfied with their lives, which was explained by their social support and coping skills. Some grandparents who assume this role likely would benefit from interventions that promote social support and coping skills.
Effect of adding interferential current stimulation to exercise on outcomes in primary care patients with chronic neck pain: a randomized controlled trial
Authors: Albornoz-Cabello Manuel , Pérez-Mármol José Manuel , Barrios Quinta Cristo Jesus , Matarán-Peñarrocha Guillermo A , Castro-Sánchez Adelaida María , de la Cruz Olivares Blanca 
Published: April 2019

Objective: To evaluate the effect of adding interferential current stimulation to exercise on pain, disability, psychological status and range of motion in patients with neck pain. Design: A single-blinded randomized controlled trial. Setting: Primary care physiotherapy units. Subjects: A total of 84 patients diagnosed with non-specific mechanical neck pain. This sample was divided into two groups randomly: experimental ( n = 42) versus control group ( n = 42). Interventions: Patients in both groups had a supervised therapeutic exercise programme, with the experimental group having additional interferential current stimulation treatment. Main measures: The main measures used were intensity of neck pain according to the Visual Analogue Scale; the degree of disability according to the Neck Disability Index and the CORE Outcome Measure; anxiety and depression levels according to the Goldberg scale; apprehension as measured by the Personal Psychological Apprehension scale; and the range of motion of the cervical spine. The sample was evaluated at baseline and posttreatment (10 sessions/two weeks). Results: Statistically significant differences between groups at posttreatment were observed for Visual Analogue Scale (2.73 ± 1.24 vs 4.99 ± 1.56), Neck Disability Index scores (10.60 ± 4.77 vs 18.45 ± 9.04), CORE Outcome Measure scores (19.18 ± 9.99 vs 35.12 ± 13.36), Goldberg total score (6.17 ± 4.27 vs 7.90 ± 4.87), Goldberg Anxiety subscale, Personal Psychological Apprehension Scale scores (28.17 ± 9.61 vs 26.29 ± 11.14) and active and passive right rotation. Conclusions: Adding interferential current stimulation to exercise resulted in better immediate outcome across a range of measures.
Aberrant functional connectivity density in patients with treatment-refractory obsessive-compulsive disorder: a pilot study
Authors: Shan Pei Wei , Liu Wei , Liu Caixing , Han Yunyi , Wang Lina , Chen Qinggang , Tian Hongjun , Sun Xiuhai , Luan Shuxin , Lin Xiaodong , Jiang Deguo , Zhuo Chuanjun 
Published: April 2019

Objective Functional connectivity (FC) is altered in patients with obsessive-compulsive disorder (OCD). Most previous studies have focused on the strength of FC in patients with OCD; few have examined the number of functional connections in these patients. The number of functional connections is an important index for assessing aberrant FC. In the present study, we used FC density (FCD) mapping to explore alterations in the number of functional connections in patients with treatment-refractory OCD (TROCD) using the FCD index. Methods Twenty patients with TROCD and 20 patients with OCD in clinical remission were enrolled in the study. Global FCD (gFCD) was adopted to compare the differences between the two groups of patients. Results The gFCD in the left middle temporal gyrus was lower in the patients with TROCD than in those with remitted OCD, suggesting that decreased information processing ability may play a significant role in TROCD. Conclusion The left middle temporal gyrus is a key component of the emotional processing circuit and attentional processing circuit. Decreased information processing ability in this brain region may play a significant role in TROCD; however, further well-designed follow-up studies are needed to support this hypothesis.
Effects of oxidative stress on blood pressure and electrocardiogram findings in workers with occupational exposure to lead
Authors: Qu Wei , Du Guo-Li , Feng Bin , Shao Hua 
Published: April 2019

Objective To observe the correlation between the oxidative stress index and cardiovascular system damage in a population with lead exposure. Methods Two populations (144 manufacturing workers and 94 administrators) from a lead–acid battery manufacturer in Shandong Province in China were recruited. The blood lead level, oxidative stress index, blood pressure, electrocardiogram findings, and their correlations were analyzed in both groups. Results The blood lead level was significantly higher in manufacturing workers than administrators (254.34 vs. 65.32 µg/L, respectively). The differences in the oxidative stress index, serum total superoxide dismutase (T-SOD) concentration, and malondialdehyde (MDA) concentration between the two populations were statistically significant. The rates of abnormal blood pressure and electrocardiogram findings were significantly higher in manufacturing workers than administrators. Workers with middle- and high-dose lead exposure had lower T-SOD and higher MDA concentrations than those with low-dose lead exposure. Significant correlations were found between the blood lead level and the MDA concentration, systolic pressure, diastolic pressure, and electrocardiogram findings. Linear multiple regression analysis showed that T-SOD was negatively associated with blood lead, electrocardiogram findings, and MDA. Conclusion Lead exposure can lead to oxidative stress, increased blood pressure, and abnormal electrocardiogram findings and may impact cardiovascular diseases through oxidative stress.
Results of the Workplace Health in America Survey
Authors: Linnan Laura A. , Cluff Laurie , Lang Jason E. , Penne Michael , Leff Maija S. 
Published: April 2019

Purpose: To provide a nationally representative snapshot of workplace health promotion (WHP) and protection practices among United States worksites. Design: Cross-sectional, self-report Workplace Health in America (WHA) Survey between November 2016 and September 2017. Setting: National. Participants: Random sample of US worksites with ≥10 employees, stratified by region, size, and North American Industrial Classification System sector. Measures: Workplace health promotion programs, program administration, evidence-based strategies, health screenings, disease management, incentives, work–life policies, implementation barriers, and occupational safety and health (OSH). Analysis: Descriptive statistics, t tests, and logistic regression. Results: Among eligible worksites, 10.1% (n = 3109) responded, 2843 retained in final sample, and 46.1% offered some type of WHP program. The proportion of comparable worksites with comprehensive programs (as defined in Healthy People 2010) rose from 6.9% in 2004 to 17.1% in 2017 ( P < .001). Occupational safety and health programs were more prevalent than WHP programs, and 83.5% of all worksites had an individual responsible for employee safety, while only 72.2% of those with a WHP program had an individual responsible for it. Smaller worksites were less likely than larger to offer most programs. Conclusion: The prevalence of WHP programs has increased but remains low across most health programs; few worksites have comprehensive programs. Smaller worksites have persistent deficits and require targeted approaches; integrated OSH and WHP efforts may help. Ongoing monitoring using the WHA Survey benchmarks OSH and WHP in US worksites, updates estimates from previous surveys, and identifies gaps in research and practice.
Epidemiology, Risk Factors, and Outcomes After Early Posttransplant Clostridiodes difficile Infection in Renal Transplant Recipients
Authors: Jorgenson Margaret R. , Descourouez Jillian L. , Yang Dou-Yan , Leverson Glen E. , Saddler Christopher M. , Smith Jeannina A. , Safdar Nasia , Mandlebrot Didier A. , Redfield Robert R. 
Published: April 2019

Background: Modifiable risk-factors associated with Clostridioides difficile infection (CDI) in renal-transplant (RTX) have not been clearly established and peri-transplant risk has not been described. Objective: Evaluate epidemiology, risk-factors and outcomes after CDI occurring in the first 90 days after RTX (CDI-90).Methods: Observational cohort study/survival analysis of adult RTX recipients from 1/1/2012-12/31/2015. Primary outcome was CDI-90 incidence/risk-factors. Secondary outcome was evaluation of post-90 day transplant outcomes. Results: 982 patients met inclusion criteria; 46 with CDI-90 and 936 without (comparator). CDI incidence in the total population was 4.7% at 90 days, 6.3% at 1 year, and 6.4% at 3 years. Incidence of CDI-90 was 5%; time to diagnosis was 19.4±25 days (median 7). Risk-factors for CDI-90 were alemtuzumab induction (Hazard ratio [HR] 1.5, 95% CI(1.1-2.0), p = 0.005) and age at transplant (HR 1.007/year, 95% CI (1.002-1.012), p= 0.007). However, risk-factors for CDI at any time were different; donation-after-circulatory-death (DCD) donor (HR 2.5 95% CI (1.3-4.9), p = 0.008) and female gender (HR 1.6 95% CI (1.0-2.7), p = 0.049). On Kaplan-Meier, CDI-90 appeared to have an impact on patient/graft survival, however when analyzed in a multivariable stepwise Cox proportional hazards model, only age was significantly associated with survival ( p = 0.002). Conclusion and Relevance: Incidence of CDI-90 is low, mostly occurring in the first post-operative month. Risk-factors vary temporally based on time from transplant. In the early post-op period induction agent and age at transplant are significant, but not after. Associations between CDI and negative graft outcomes appear to be largely driven by age. Future studies validating these risk-factors as well as targeted prophylaxis strategies and their effect on long term graft outcomes and the host microbiome are needed.