bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation between plasma concentrations of tramadol and its metabolites and the incidence of seizure in tramadol-intoxicated patients
Authors: Ahmadimanesh Mahnaz , Shadnia Shahin , Rouini Mohammad Reza , Sheikholeslami Behjat , Ahsani Nasab Sara , Ghazi-Khansari Mahmoud 
Published: May 2018

Abstract

Background:
Seizure is one of the important symptoms of tramadol poisoning, but its causes are still unknown. The aim of this study is to find a relationship between tramadol and the concentrations of its metabolites versus the incidence of seizures following the consumption of high doses of tramadol.

Methods:
For this purpose, the blood samples of 120 tramadol-intoxicated patients were collected. The patients were divided in two groups (seizure and non-seizure). The concentrations of tramadol and its metabolites (M1, M2 and M5) were measured by using a high-performance liquid chromatography method. The relationship between tramadol and the levels of its metabolites and seizure incidences was also investigated.

Results:
In 72% of the patients, seizures occurred in the first 3 h after the ingestion of tramadol. The seizure incidences were significantly correlated with the patients’ gender, concentrations of tramadol, M1 and M2 and the history of previous seizures (p<0.001). The average concentration of M2 was significantly higher in males (p=0.003). A previous history of the use of sedative-hypnotics and the co-ingestion of benzodiazepines and other opioids were shown to significantly decrease the rate of seizure. The rate of seizure was directly related to the concentrations of tramadol and its metabolites. Higher M2 concentration in males can be considered a reason for increased incidences of seizures in males. The plasma concentration of M1 affected the onset of seizure.

Conclusions:
Therefore, it can be concluded that differences in the levels of the metabolites can affect the threshold of seizure in tramadol-intoxicated patients.
8-Prenylnaringenin from hop (Humulus lupulus L.) – a panacea for menopause?
Authors: Minecka Aldona , Zych Maria , Kaczmarczyk-Sedlak Ilona 
Published: May 2018

Summary
8-Prenylnaryngenin (8-PN) is the strongest known phytoestrogen (PE). Its main source is the female inflorescences of hops (Humulus lupulus L.). 8-PN, which, in contrast to other PEs, is proven to have stronger activity and higher affinity for the α subtype of estrogen receptor (ER). Therefore, it may be an effective substitute for hormone replacement therapy (HRT). The studies in postmenopausal women have shown its particular effectiveness in reducing hot flashes. However, a strong stimulation of uterus by 8-PN may be associated with the occurrence of adverse effects (eg. bleeding) and increase the risk of carcinogenesis. The H. lupulus extracts preparations are currently supplements which makes control of the doses used and thus increases the occurrence of uncontrolled self-treatment difficult. This paper presents the current knowledge on 8-PN and discusses the potential risks associated with use of hops to alleviate the symptoms of menopause.
Illegal Earnings
Authors: Goudkamp James , König Lorenz 
Published: May 2018

AbstractThis article addresses the principles of tort law that govern claims in respect of lost illegal earnings. It focuses on common law jurisdictions (and the law in the United Kingdom in particular) where such claims, despite apparently being commonplace, have been largely ignored by academics. It describes the existing law and calls in aid in this regard a four-fold taxonomy of cases. The article then turns attention to how claims in respect of lost illegal earnings ought to be decided. At this juncture, the article looks to ideas emanating from German tort law, which has developed a highly sophisticated jurisprudence on the subject of illegal earnings. The German approach, stated simply, requires tort law to defer to rules in other departments of private law. If, for example, contract law would not protect an interest that a claimant has in a particular transaction by reason of the transaction being tainted with illegality, tort law will not allow a claimant indirectly to obtain the benefits of that transaction via a claim for lost illegal earnings. It is argued that the German solution holds considerable promise and merits consideration as a serious alternative to the significantly more complicated principles that the common law courts have developed, which principles currently lack any thoroughgoing rationalisation.
i-Vector-Based Speaker Verification on Limited Data Using Fusion Techniques
Authors: Jayanthi Kumari T.R. , Jayanna H.S. 
Published: May 2018

Abstract
In many biometric applications, limited data speaker verification plays a significant role in practical-oriented systems to verify the speaker. The performance of the speaker verification system needs to be improved by applying suitable techniques to limited data condition. The limited data represent both train and test data duration in terms of few seconds. This article shows the importance of the speaker verification system under limited data condition using feature- and score-level fusion techniques. The baseline speaker verification system uses vocal tract features like mel-frequency cepstral coefficients, linear predictive cepstral coefficients and excitation source features like linear prediction residual and linear prediction residual phase as features along with i-vector modeling techniques using the NIST 2003 data set. In feature-level fusion, the vocal tract features are fused with excitation source features. As a result, on average, equal error rate (EER) is approximately equal to 4% compared to individual feature performance. Further in this work, two different types of score-level fusion are demonstrated. In the first case, fusing the scores of vocal tract features and excitation source features at score-level-maintaining modeling technique remains the same, which provides an average reduction approximately equal to 2% EER compared to feature-level fusion performance. In the second case, scores of the different modeling techniques are combined, which has resulted in EER reduction approximately equal to 4.5% compared with score-level fusion of different features.
Lack of Association between Angiotensin Converting Enzyme I/D Polymorphism and Unexplained Recurrent Miscarriage in Saudi Arabia
Authors: Al-Mukaynizi Fatimah Basil , AlKhuriji Afrah , Babay Zaineb , Addar Mohammad , AlDaihan Sooad , Alanazi Mohammad , Warsy Arjumand S. 
Published: May 2018

Summary
Background: An insertion/deletion (I/D) polymorphism in the angiotensin converting enzyme (ACE) gene has been associated with recurrent miscarriage (RM) in several populations. We initiated this study to determine the association, if any, between the I/D polymorphism of ACE gene and RM in Saudi females.
Method: This study was conducted on 61 Saudi females suffering from RM (mean age: 34.1±6.2 years; range 15–45) attending clinics at King Khalid University Hospital, and 59 age matched females who had at least 2 children, as controls. Blood samples were drawn in EDTA tubes by venipuncture. DNA was extracted using the Puregene DNA purification kits. Insertion/Deletion (I/D) polymorphism of ACE gene was investigated by amplifying the genomic DNA by PCR using gene-specific primers. A single 190 bp or 490 bp band was obtained in the homozygous cases for the D allele or I allele, respectively, while the presence of both 190 and 490 bp bands indicated heterozygosity (ID).
Statistical analysis: Deviation from Hardy-Weinberg equilibrium was determined (http://ihg.gsf.de/cgi-bin/hw/hwa1.pl). A standard chi-square (χ2) test was used for comparing the genotype and allele frequencies in the two groups and Students‘t’ test and χ2 test were employed to compare values between the two groups. P<0.05 was considered statistically significant.
Results: The frequencies of DD, ID, and II genotypes were 56.7%, 29.5% and 4.9%, respectively, in females with RM and 54.2%, 42.3% and 3.3% respectively in the control group, but the difference was not statistically significant.
Conclusion: In some populations, meta-analyses showed an association between I/D polymorphism and RM risk, and the D allele was implicated as an increased risk factor for RM. However, this association was not apparent in the Saudi females.
Ortega y Gasset on Georg Cantor’s Theory of Transfinite Numbers
Authors: Rabi Lior 
Published: May 2018

Abstract
Ortega y Gasset is known for his philosophy of life and his effort to propose an alternative to both realism and idealism. The goal of this article is to focus on an unfamiliar aspect of his thought. The focus will be given to Ortega’s interpretation of the advancements in modern mathematics in general and Cantor’s theory of transfinite numbers in particular. The main argument is that Ortega acknowledged the historical importance of the Cantor’s Set Theory, analyzed it and articulated a response to it. In his writings he referred many times to the advancements in modern mathematics and argued that mathematics should be based on the intuition of counting. In response to Cantor’s mathematics Ortega presented what he defined as an ‘absolute positivism’. In this theory he did not mean to naturalize cognition or to follow the guidelines of the Comte’s positivism, on the contrary. His aim was to present an alternative to Cantor’s mathematics by claiming that mathematicians are allowed to deal only with objects that are immediately present and observable to intuition. Ortega argued that the infinite set cannot be present to the intuition and therefore there is no use to differentiate between cardinals of different infinite sets.
Names on maps as an element of the discussion about relativism in the understanding of national identity (based on the example of western and northern Polish territories after 1945 and 1989)
Authors: Konopska Beata , Bogacz Teresa 
Published: May 2018

Abstract
The article tackles the difficult problem of identity creation of new inhabitants of western and northern Poland after 1945 and of relativism in the understanding of national identity after 1989. One of the manifestations are geographical names, which are reflected on maps. The authors of the article looked at this difficult, historically unprecedented process of integration and identification of new inhabitants with the geographical space through the prism of maps, entering into the contemporary discussion about the transformations taking place in the understanding of national identity.
A Note on Borders, Dyads and the Distribution of Democracy in Sub-Saharan Africa
Authors: Pontarollo Nicola , Ricciuti Roberto 
Published: May 2018

Abstract
In this note we use dyadic data to address the issue of the spread of political regimes in Sub-Saharan Africa from 1977 to 2014. Dyadic data are binary relationship between countries and provide a data-rich environment for the study of international relations. We address the issue of correlation between these dyadic observations, which generates a cluster of dependent observations associated with that country. We find that borders matter, since often the effect of home- and foreign-grown variables have differentiated effects on democracy in one country.
Adverse reactions of hyperbaric oxygen therapy - case description of a generalised seizure
Authors: Grobelska Kinga , Betyna Monika , Zieliński Ewa 
Published: May 2018

Abstract
Hyperbaric oxygen therapy (HBOT) is a safe treatment, provided fulfilling certain rules of patient qualifications to treatment, as well as supervision over the course of therapy by qualified medical staff. Side effects reported in the literature are rare, and are usually mild and transient. Professional medical staff allows minimising the adverse events occurrence. The scale of complications is unknown, especially in Polish hyperbaric center. Careful analysis could be used to develop prevention procedures for patients of hyperbaric oxygen therapy. Hyperbaric Oxygen Centre and Wound Treatment in Bydgoszcz during 28 months performed hyperbaric oxygen therapy (HBOT) in case of 423 patients. During this period, adverse events occurred occasionally. 17 cases have been reported. Authors described study case 77 year-old patient who was admitted due to non-healing wound-left lower abdomen (state after radiotherapy). During the fourth session, on decompression phase patient have had a generalized seizure (tonic-clonic). The decompression was stopped, the oxygen supply was disconnected but only after the drug administration seizures terminated. The most likely causative agent of the adverse reactions of the patient treated with HBOT was the oxygen toxic effect on the brain tissue. However, analyzing the circumstances of the seizure termination: phase of decompression at the pressure 2ATA and lack of oxygen disconnection response, it cannot be excluded other causes of this complication.
A systematic review of micro correlates of maternal mortality
Authors: Yakubu Yahaya , Mohamed Nor Norashidah , Abidin Emilia Zainal 
Published: May 2018

AbstractIn the year 2000, the World Health Organization launched the Millennium Development Goals (MDGs) which were to be achieved in 2015. Though most of the goals were not achieved, a follow-up post 2015 development agenda, the Sustainable Development Goals (SDGs) was launched in 2015, which are to be achieved by 2030. Maternal mortality reduction is a focal goal in both the MDGs and SDGs. Achieving the maternal mortality target in the SDGs requires multiple approaches, particularly in developing countries with high maternal mortality. Low-income developing countries rely to a great extent on macro determinants such as public health expenditure, which are spent mostly on curative health and health facilities, to improve population health. To complement the macro determinants, this study employs the systematic review technique to reveal significant micro correlates of maternal mortality. The study searched MEDLINE, PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Science Direct, and Global Index Medicus of the World Health Organization. Our search was time framed from the 1st January, 2000 to the 30th September, 2016. In the overall search result, 6758 articles were identified, out of which 33 were found to be eligible for the review. The outcome of the systematic search for relevant literature revealed a concentration of literature on the micro factors and maternal mortality in developing countries. This shows that maternal mortality and micro factors are a major issue in developing countries. The studies reviewed support the significant relationship between the micro factors and maternal mortality. This study therefore suggests that more effort should be channelled to improving the micro factors in developing countries to pave the way for the timely achievement of the SDGs’ maternal mortality ratio (MMR) target.
Determinants and Inverses of Ppoeplitz and Ppankel matrices
Authors: Zuo Baishuai , Jiang Zhaolin , Fu Deqian 
Published: May 2018

Abstract
In this paper, we consider two kinds of special matrices, which are called Ppoeplitz matrix and Ppankel matrix. The idea of matrix transformation is used to compute the determinants and inverses of the Ppoeplitz matrix and the Ppankel matrix. We develop efficient formulas for inverting the Ppoeplitz matrix and the Ppankel matrix. Specifically, for inverting the Ppoeplitz matrix and the Ppankel matrix using our proposed formulas, which only 11 entries need to be calculated when n is even, only 12 entries need to be calculated when n is odd. An example is given to illustrate the formulas.
Anion-Cation Replacement Effect on the Structural and Optoelectronic Properties of the LiMX2 (M = Al, Ga, In; X = S, Se, Te) Compounds: A First Principles Study
Authors: Khan Amjad , Sajjad M. , Murtaza G. , Laref A. 
Published: May 2018

Abstract
In the chalcopyrite (or tetragonal) phase, different physical properties of the ternary LiMX2 (M = Al, Ga, In and X = S, Se, Te) compounds are studied by the very accurate density functional method. The optimized lattice constants and the bandgaps are close to the existing experimental data. In addition, for most of the LiMX2 compounds, when the cations change from Al to In and anions from S to Te, the lattice constant and equilibrium volume for the crystal unit cell increase whereas the bulk modulus decreases. Using different generalized gradient approximations, the band structure calculations are performed. Generally, it was observed that there exists a decreasing tendency of the bandgap energies except for the LiAlSe2, LiInSe2, and LiGaTe2 compounds due to the change from Al to In as well as the change from S to Te. The bonding analysis shows that ionic bonds are present between the Li-X atoms, while a covalent bond exists between the M cations and X anions. The optical properties of the compounds are studied by calculating the real and imaginary components of the refractive index, reflectivity, optical conductivity, and birefringence. In addition, the optical properties from the calculations show that these materials are appropriate applicants to be utilized as Bragg’s reflector or applied in optoelectronic and solar cell technology.
Smart Cement Compressive Piezoresistive, Stress-Strain, and Strength Behavior with Nanosilica Modification
Authors: Vipulanandan C. , Mohammed A. 
Published: May 2018

Abstract
In this study, smart cement with a water-to-cement ratio of 0.38 was modified with up to 1 % silica nanoparticles (NanoSiO2) to evaluate the effect not only on the sensing properties but also on the compressive stress-strain relationship and strength. The oil well cement (class H) and cement modified with NanoSiO2 were characterized using X-ray diffraction analysis and thermal gravimetric analysis. The smart cement was prepared by adding 0.1 % of the conductive filler based on the percolation theory concept to make the cement piezoresistive yet remain a nonconductive material. Testing evaluated the smart cement behavior with and without NanoSiO2 to verify the sensitivity of electrical resistivity changes with time and compressive loading. The addition of 0.5 and 1 % NanoSiO2 increased the initial electrical resistivity of the smart cement by 17 and 35 %, respectively. In one day, the maximum change in the electrical resistivity (RI24hr) for the smart cement without NanoSiO2 was 364 %. The RI24hr for the smart cement with NanoSiO2 decreased with the amount of NanoSiO2. The addition of 1 % NanoSiO2 increased the compressive strength of the smart cement by 14 and 42 % after 1 and 28 days of curing, respectively. The nonlinear Vipulanandan p-q curing model was used to predict the changes in electrical resistivity with curing time. The piezoresistivity of smart cement with NanoSiO2 was over 500 times higher than the regular cement, depending on the curing time and NanoSiO2 content. The Vipulanandan p-q stress strain and stress change in resistivity models also predicted the experimental results very well. For smart cement modified with NanoSiO2, the resistivity change at peak stress was over 1,250 times higher than the change in the compressive strain. A linear correlation was obtained between the RI24hr and the compressive strength of the modified smart cement based on the curing time.
PENERAPAN SIMULASI GARDU TOL KONVENSIONAL DAN OTOMATIS PADA GERBANG TOL FATMAWATI 2
Authors: Ningsih Wulandari Retno , Hakim Lukman , Hakiem Nashrul 
Published: May 2018

ABSTRAK Jalan tol adalah bagian dari Jalan Nasional yang perlu dijaga agar tetap berfungsi optimal. Penelitian ini dilakukan di Gerbang Fatmawati 2, yang merupakan salah satu segmen jalan tol terbesar pada bulan Agustus 2017 dan hanya memfasilitasi 2 gardu layanan konvensional yang mengakibatkan penumpukan antrian. Untuk upaya untuk mengurangi panjang antrian di Gerbang Tol, dilakukan simulasi perbandingan antara penggunaan gardu tol konvensional dengan otomatis. Metode yang digunakan dalam simulasi ini adalah metode antrian. Simulasi dilakukan menggunakan perangkat lunak promodel dengan 3 skenario yaitu Konvensional Tube-Konvensional, Konvensional-Otomatis dan Otomatis-Otomatis. Kemudian hasil simulasi di uji dengan perbandingan lebih dari 2 sistem yaitu tes bonferroni. Dari hasil tes Bonferroni dapat disimpulkan dari tiga skenario di atas bahwa gardu tol-otomatis konvensional memiliki hasil terbaik karena dengan panjang dan panjang waktu antrian yang ada memiliki hasil utilitas yang memadai. ABSTRACT The toll road is part of the National Road which needs to be maintained in order to keep it functioning optimally. The study was conducted at Fatmawati 2 Gate, which is one of the largest toll road segments in August 2017 and only facilitated 2 conventional service substations resulting in the buildup of queues. In order to reduce the length of the queue at the Toll Gate, a simulation which compared the use of conventional toll with automatic toll was conduct. Method used using queuing method. The simulation is done using promodel software with 3 scenarios are Conventional Tube-Conventional, Conventional-Automatic and Automatic-Automatic. Then the result of simulation in test with comparison more than 2 system that is Bonferroni test. From the bonferroni test results can be deduced from the three scenarios above that conventional toll-automatic substations have the best results because with the length and length of time the existing queue has sufficient utility results. How To Cite : Ningsih, W.R. Hakim, L. Hakiem, N. (2018). PENERAPAN SIMULASI GARDU TOL KONVENSIONAL DAN OTOMATIS PADA GERBANG TOL FATMAWATI 2. Jurnal Teknik Informatika, 11(1), 95-108. doi 10.15408/jti.v11i1.7032 Permalink/DOI: http://dx.doi.org/10.15408/jti.v11i1.7032
TAILORING THE STRUCTURE AND MORPHOLOGY OF WO3 NANOSTRUCTURES BY HYDROTHERMAL METHOD
Authors: Lan Anh Luu Thi 
Published: May 2018

Tungsten oxide nanostructures were synthesized by hydrothermal and acid precipitation (hydrothermal at room temperature) methods without using any supporting agent or structure-directing reactant. The morphology and crystalline structure of nanostructures strongly depended on pH of the precursor solution and synthesis method. With pH = -1.0, using acid precipitation method, orthorhombic nanoplate was observed. Using hydrothermal method, with the pH = - 1.0, we obtained directly stable monoclinic nanoparticle WO3. With pH = 1.1, the mixing of nanoparticle and nanorod with the hexagonal frame was acquired. When pH reaches to 1.7, only bundle of hexagonal nanorods was observed. To characterize the morphology and structure of tungsten nanostructures, we used Field Emission Scanning Electron Microscopy, X-ray diffraction, and micro Raman spectroscopy. The micro Raman spectroscopy was used to support the X-ray diffraction analysis. These results imply that adjusting pH is an efficient and promising method to manipulate both morphology and crystal structure of WO3 nanostructure for selective applications.