bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vestibular Rehabilitations Therapy (VRT) in Patients with Persistent Postural Perceptual Dizziness (PPPD)
Authors: Kamal Ibrahim Nadia Mohamed , Abdelmonem Hazza Nagwa Mohamed , Galal Eman Mohamed , Yaseen Dhiaa Mohammed 
Published: November 2024

Abstract

Background
Persistent functional dizziness has been known for many years under various names, including phobic postural vertigo (PPV), visual vertigo and chronic subjective dizziness (CSD). In response to an initiative by the Bárány Society 2017, these terms have recently been grouped together under the umbrella term ‘Persistent Postural-Perceptual Dizziness PPPD' and have been given their own diagnostic criteria.

Aim of the Work
To evaluate posture and cognitive functions in patients with PPPD and to study the efficacy of VRT for management of abnormal postural control in patients with PPPD utilizing subjective and objectives outcome measures.

Materials and Methods
Thirty-three PPPD patients participated in this study. Selection of study group was based on the diagnostic criteria for PPPD proposed by Barany society shown in the International Classification of Vestibular Disorders (ICVD) 2017. Every patient was subjected to history taking, cognitive functions assessment (Mini Mental State Examination and Anxiety and Depression Assessment), Arabic Version of Dizziness Handicap Inventory (DHI), vestibular laboratory tests: Videonystagmography VNG, Video Head Impulse vHIT, cervical and ocular Vestibular Evoked Myogenic Potentials, and Computerized Dynamic Posturography CPD). All patients received Vestibular Rehabilitations Therapy (VRT). Assessment of VRT outcome was conducted by DHI and SOT after 6 weeks of VRT.

Results
Unsteadiness (91%), dizziness (85%), and non-spinning vertigo (76%) were the three main symptoms of PPPD patients. Additionally, patients with PPPD demonstrated questionable (39.4%) and mild cognitive impairment (30.3%). According to vestibular laboratory tests, (42.4%) of patients had peripheral vestibular abnormality, (30.3%) showed normal laboratory test. There was statistically significant difference between before and after VRT as regards DHI and all the sensory analysis of posturography conditions of (SOT).

Conclusion
Supervised sessions using smart CDP systems and home- based VRT were effective in improving patients with PPPD evidenced by subjectively improved DHI scores and objectively improved SOT results.
The Effect of Orbital Exenteration on the Management of Rhino-Orbito-Cerebral Mucormycosis
Authors: Abdel Azeem Mansour Ossama Ibrahim , Ali Nasr Askoura Anas Mohamed , Kamel Abdel Aty Ahmed Mohamed , Elsayed Elsayed Mohamed Mohamed 
Published: November 2024

Abstract

Background
Rhino-orbito-cerebral mucormycosis (ROCM) is a life-threatening acute angio- invasive fungal infection caused by Mucoraceae family. in immunocompromised individuals. Fungal inoculation starts in the nose and paranasal sinuses and then infiltration of the surrounding bone and soft tissues when it reaches the orbit or the brain, fatal complications may follow. The management of ROCM needs a multi disciplinary approach containing sino-nasal and orbital endoscopic debridement along with systemic antifungal drugs. when the orbit is severely affected, immediate orbital exenteration is a must to enhance the patient’s survival and limit the spread of the disease.

Aim of the Study
The aim of this systematic review is to identify the effect of orbital exenteration in the management of orbital invasion in ROCM patients on the improvement of patient survival and prognosis.

Patients and Methods
Studies included are Retrospective observational and prospective studies conducted in the last 20 years Participants included: Patients with ROCM fulfilling the clinical, radiological and pathological/microbiological criteria for diagnosis with ROCM

Results
Orbital exentration halts ROCM progression and overall Survival rates of orbital exentration have been improved in last 20 years becoming as high as 82.6 % in our study. Survival rates of orbital exenteration in ROCM patients after Covid 19 were 84.5% compared to 60.6% before covid 19. Also the recovery time reduced to 36.6 days in this metalysis with a promising results in reconstructive surgeries for cosmetic and psychological efforts.

Conclusion
Orbital exentration together with medical treatment and sinus debridement control ROCM progression. Patients’ survival and recovery time have been enhanced using this aggressive procedure. No guidelines is found concerning when the exenteraton should be done
The Effect of Vitamin D Supplementation on Insulin Resistance and Progression from Prediabetes to Diabetes Mellitus: A Systematic Review/Meta-Analysis
Authors: Hassan Anan Ahmed , Eid Yara Mohamed , Abou Shady Manal Mohamed , Abdelsalam Mona Mohamed , Mohammad Salwa Mostafa , Mohamed Sherihan Aboelyazed 
Published: November 2024

Abstract

Background
Emerging evidence suggests that altered vitamin D and calcium homeostasis play a role in type 2 diabetes mellitus development. Binding of vitamin D to its receptors stimulates the expression of insulin receptors and activates glucose transporters. Additionally, vitamin D regulates calcium concentration in β-cells, which enhances insulin secretion.

Objective
To evaluate the effect of vitamin D supplementation on insulin resistance and glycemic control in prediabetes.

Materials and Methods
We searched databases including CENTERAL, Medline (PubMed), Web of Science, EMBASE and Egyptian Knowledge Bank (EKB) for randomized controlled trials (RCTs) comparing vitamin D or it’s analogues with placebo, RCTs published in English language until December 2022 were included, participants were adults (≥18 years old) with laboratory-confirmed diagnosis of prediabetes by fasting blood glucose (FBG) and/or 2-hour plasma glucose after an oral glucose tolerance test (OGTT) and glycosylated hemoglobin (HbA1c). A total of 3616 studies were retrieved, and 3603 were excluded due to different populations, exposures, or languages. Studies with different outcomes, cross-sectional studies, cohort studies, case reports, case series, and commentaries, along with studies conducted on animals, were also excluded. Thirteen randomized controlled trials were included in this systematic review using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for reporting.

Results
Included thirteen RCTs showed improvement in FBG (Pooled standardized mean difference (SMD): −1.239, 95% confidence interval (CI): −1.858, −0.621, P value: &lt;0.001), HbA1c (SMD: −0.736, 95% CI: −1.225, −0.246, P value: 0.003) and, OGTT (SMD: −0.665, 95% CI: −1.237, −0.094, P value: 0.023) respectively. Regarding heterogeneity, random effect model was considered as per I2 statistics for each FBG (96.52%, P value: &lt;0.001), HbA1c (94.52%, P value: &lt;0.001) and, OGTT (95.00%, P value:&lt;0.001) respectively.

Conclusion
Vitamin D supplementation reduced the risk of new-onset type 2 diabetes mellitus. Additionally, it might boost the rate at which prediabetes returns to normal.
Application of Digital Vernier Caliper on Adult Egyptians’ Dental Arches for Age and Sex Identification
Authors: Salem Fatma M , Messih Mary S Abdel , Hadhoud Rania M 
Published: November 2024

Abstract

Background
Forensic odontology is the application of the science of dentistry to the field of criminal and civil laws. Dental arch dimensions are used in forensic medicine to aid the identification of living humans and their remains in severe conditions and mass disasters due to the survivability and diversity of dental structures.

Aim
This study aimed to determine and evaluate the usefulness of inter-canine, inter-molar arch widths, and arch depth of the mandible for age and sex identification in adult Egyptian samples.

Methods
This is a prospective study involving 150 Egyptian adult patients (75 male and 75 females) who attended the dental clinic at Ain Shams University Dental Hospital during the period from the beginning of October 2020 to the end of September 2021. Aged from 8 to 50 years and divided into 3 age groups. Both jaw impressions were taken with alginate and study models were prepared, inter canine, intermolar widths, and total arch length were measured in all the cases, and findings were tabulated.

Results
The current study showed a high statistically significant difference between the maxilla and the mandible as regards the ICW, IMW, and TAL dimensions (P value&lt;0.001), all the study measures were higher for males than females in both maxilla and mandible in the three age groups. Maxillary and mandibular inter- canine intermolar widths were statistically significant in sex identification in most age groups, either together or separately, but for total arch length, both jaws are needed to identify sex in all age groups specifically males in the first and third age groups.

Conclusion
Both dental arches’ dimensions (ICW, IMW &TAL) are dependable specific parameters for age and sex identification in adult Egyptians. Recommendation: Further studies are needed to assess different arches forms in the Egyptian population, especially with the presence of other ethnic groups now in Egypt. to identify correlations between the different parameters measured in this study to establish the interactions among them in the human face growth and effect on victim identification.
Assessment of Low Cost Laparascopic Appendectomy A Comperative Study between Intracorporeal Ligation and Clipping to Secure Appendicular Stump
Authors: Nyaz Saad Emad Samuel , Farouk Abadeer Ashraf , Ragheb Ayoub Bishoy Refaat 
Published: November 2024

Abstract

Background
The first laparoscopic appendectomy was done in the 1970s by gynecologists. The standard operation of acute appendicitis is laparoscopic appendectomy where minimal invasive surgery is performed.

Objective
To compare between clipping and intra-corporeal ligation of appendicular stump regarding safety, timing of operation, difficulty, any post operative complication and cost.

Patients and Methods
This was a prospective randomized clinical study will be conducted in Ain Shams University hospitals that was conducted on 100 cases of acute appendicitis that were subjected to laparoscopic appendectomy. They were divided into two groups. Group 1 (50 patients) ligation group. Group 2 (50 patients): clip group.

Results
Our study revealed that, median operative time for intracorporeal ligation group is 55.6 minutes. Median operative time for titanium clips group is 46.44 minutes with highly statistically significant difference. The present study showed that, there was no statistically significant difference between the two group regarding post-operative hospital stay and return to work. In this study, there is no big difference in the total post-operative complications between clipping and intra- corporeal ligation groups.

Conclusion
Both methods of intracorporeal ligation and clip application are cost effective in securing the appendicular stump. metal clip application is more easy to the surgeon, more time saving during the operation and less post-operative stay in the hospital. The only limitation of the clip application is the wider diameter of the base of the appendix beyond the large titanium clip in these cases intra-corporeal ligation is a safe and cheap alternative.
Short Term Detection of Gastroesophageal Reflux Disease after Laparoscopic Sleeve Gastrectomy
Authors: Mohamed Abdel-Salam Mostafa Mamdouh , Moustafa Alaa Abbas Sabry , Youssef Ahmed Helmy , Eskandaros Moheb Shoraby 
Published: November 2024

Abstract

Background
Obesity has become one of the most important public health problems in the United States and many other resource-rich countries and transitional economies. As the prevalence of obesity increased, so did the prevalence of the comorbidities associated with obesity. For this reason, it is imperative that health care providers identify overweight and obese patients so that counseling and treatment can be provided.

Objective
Short term detection of gastroesophageal reflux disease (GERD) in morbidly obese patients after being subjected to laparoscopic sleeve gastrectomy (LSG).

Methods
This prospective case series study was carried out on 60 patients was conducted in Surgery Department, Ain Shams University Hospitals Bariatric Surgery unit in the period from June 2018 till June 2021.

Results
Our finding of GERD occurrence was 26.67% (16/60) of patients. So, if GERD with erosive esophagitis or Barrett esophagus or incompetent LES is diagnosed, SG shouldn’t be done. In these clinical situations that are independent of the BMI, Roux en-Y gastric bypass is indicated. Only in a very special group of patients with BMI between 30 and 35 and comorbidities, SG plus other antireflux procedure or hiatal hernia repair is accepted.

Conclusion
There is an agreement with other reports about importance of exclusion of GERD or hiatal hernia preoperatively. We recommend endoscopy before any operation for obesity to exclude hiatal hernia, esophagitis or Barrett esophagus.
Evaluation of Efficacy and Versatility of Wise Pattern Mammoplasty Technique versus Wide Local Excision in Treatment of Upper and Lower Pole Breast Cancer, A Prospective Comperative Study
Authors: Hussein Mostafa Said , Amer Hazem Abdelsalam , Fahmy Karim , Hanafy Dina Mohamed 
Published: November 2024

Abstract

Background
Breast cancer is the most prevalent malignancy in women. Annually, an estimated 2.3 million new cases of breast cancer are identified worldwide. The objective of this research was to compare between the Wise pattern therapeutic mammoplasty and wide local excision in treatment of upper and lower poles breast tumors regarding cosmetic results, oncological outcomes, complications, recurrence and degree of satisfaction of the patients.

Methods
This prospective comparative study was conducted on 40 cases who had upper pole breast cancer (T1-2N0-1M0), lower-quadrant breast cancer, (T1-2N0-1M0]. They were divided into two equal groups: Wise pattern therapeutic mammoplasty group: patients underwent Wise pattern therapeutic mammoplasty (including superior and inferior pedicles). Wide local excision group: patients underwent direct wide local excision.

Results
Recurrence was insignificantly different between Wise patten therapeutic mammoplasty technique and wide local excision technique (P value = 0.5533). Satisfaction was significantly better in Wise patten therapeutic mammoplasty technique than wide local excision technique (P value = 0.024).

Conclusions
despite a longer duration of surgery, the Wise pattern therapeutic mammoplasty technique did not result in increased complications such as non-viable nipple- areolar complex, wound infection or seroma, compared to wide local excision. Therefore, the Wise pattern therapeutic mammoplasty technique appears to be a favorable surgical option for the management of upper and lower pole breast tumors, offering better oncological outcomes and improved cosmetic results with high patient satisfaction, without compromising safety or increasing morbidity.
Evaluation of Laparoscopic Banded One-Anastomosis Gastric Bypass (LB-OAGB); A Retrospective Study
Authors: Zakaria Mahmoud , Matar Mohamed Mohamed , Abou El-Wafa Yahya Zakaria MohamedAli , Morsy Omar Mahmoud Ahmed 
Published: November 2024

Abstract

Background
Laparoscopic one anastomosis gastric bypass (L-OAGB) is a relatively new procedure for the treatment of morbid obesity and related comorbidities. On average, this procedure results in good postoperative weight loss with a low complication rate. Recent publications suggest that dumping syndrome and weight regain might be reduced by placing a silicone ring over the gastric pouch during the procedure, so called laparoscopic banded one anastomosis gastric bypass (LB- OAGB).

Objective
To evaluate the outcomes of the LB-OAGB as regards efficacy and safety in a 12-month postoperative follow up period.

Patients and Methods
This is a descriptive retrospective study conducted in Ain Shams University Hospitals, including 20 patients. They were examined and investigated for weight loss after 1, 6 and 12 months, postoperative complications, comorbidities resolution and malnutrition after 6 months.

Results
14 Female and 6 male patients were included with a mean age of 38.7 years (24–58), mean preoperative body mass index of 46.221 kg/m2 (39.2–56), and mean preoperative weight of 132.5 kg (112–160). 7 patients presented with type 2 diabetes (35%), 5 patients (25%) diagnosed with hypertension and 1 (5%) patient with hyperlipidemia were included. No patienst required reoperation. The hospital stay was one day for 19 patients (95%), while there was 1 patient (5%) who was discharged from hospital after three days due to abdominal colics of irritable bowel syndrome (IBS). In that period, no patient required ring removal or conversion to Roux-en-Y gastric bypass surgery. Food intolerance/ vomiting wasn’t present in any patient (0%), bile reflux was present in 2 patients (10%), 1 patient (5%) presented with alkaline reflux that was readmitted and underwent conservative treatment, and no stomal ulcers were observed. Mean % excess weight loss at 6 and 12 months was 55.72% and 77.36%, respectively. All patients with the reported preoperative comorbidities had a complete resolution of comorbidities. As regards postoperative nutritional deficiencies, we had no cases (0%) diagnosed with anemia, hypoalbuminemia, or iron deficiency. We had one patient (5%) with vitamin D deficiency, and another patient (5%) with hypocalcemia. Both of those patients were not completely compliant on the regular postoperative multivitamin supplements.

Conclusion
Laparoscopic banded One Anastomosis Gastric Bypass is a safe and efficacious procedure with excellent preliminary short-term results. Weight loss in the first year is durable, and dumping syndrome and bile reflux are limited. It also proved effective as regards comorbidities resolution such as DM, HTN and hyperlipidemia, and in case of complications, the ring can be easily removed laparoscopically.
The Effect of a Telegeriatrics Post Discharge Follow Up Model on the Outcome of Acute Care Patients
Authors: Kordy Seham Saad Abd Elsattar , Sweed Hala Samir , Wahba Hoda Mohamed Farid , Shaltoot Heba Mohamed Hamed 
Published: November 2024

Abstract

Background
The post discharge period is a critical time for vulnerable patients, like the elderly, prone to unnecessary readmissions. This is mainly because post discharge care continuity is often interrupted after hospital care. The implementation of close monitoring and effective communication strategies has proven to be effective in mitigating adverse events and reducing the incidence of readmissions. Due to the pressing need for medical care that is both cost-effective and time-efficient, there has been a growing interest in exploring remote or telehealth methods for delivering healthcare services.

Aim
To assess the effect of a telegeriatrics post discharge follow up service on the primary outcome measures of patients as regard rate of readmission, mortality rate, and complications from the disease or medications.

Patients and Methods
A prospective descriptive study that was conducted from June 2021 till January 2023 on a total of 139 elderly patients discharged from the acute care units of Ain Shams University Hospitals. We collected data using asynchronous telemedicine (WhatsApp) and synchronous method (phone). The follow up was at 2 weeks, 1 month, 3 months and 6 months post discharge.

Results
Hypertension was the most frequent comorbidity (71.9%). Cases that followed up by both methods of telemedicine had better compliance than cases that only followed up using synchronous telemedicine (90.8% vs. 57.9%). They were also less likely to require hospital care (28.3% vs. 52.6%). They also suffered less complications from disease (20.0% vs. 52.6%) and lower risk of all-cause mortality (7.5% vs. 15.8%).

Conclusion
Telemedicine is a valuable tool. Using a post-discharge protocol of both synchronous and asynchronous methods of telemedicine improves patients’ compliance and outcomes.
A Histological Study on the Effect of Oral Collagen on Age Related Skin Changes in Female Albino Rats
Authors: Farid Hend , El-Alim Mohammed Somaya Abd , Shaker Safaa Mohammed , El-Din Dalia Alaa 
Published: November 2024

Abstract

Background
Skin is the mirror of aging. Therefore, for many people, especially females, a considerable amount of daily expense is occupied by cosmetics and pharmaceuticals attempting to prevent or reverse skin aging. Nowadays; researches are directed at naturally occurring substances such as collagen hydrolysate (CH). Due to its high solubility, low molecular weight, high bioavailability, as well as a wider range of functional and biological properties, CH can be used in drinks and as a jelly-like form, making it ideal as a food supplement being easily digestible, highly absorbed and distributed in the human body.

Aim
Histological assessment of the possible role of oral collagen peptides on age related skin changes in female albino rats.

Materials and Methods
Twenty female albino rats were used. they were divided into two groups, Group I which included 5 rats 5-6 months age, and Group II which included 15 rats 18-20 months age, they were further subdivided into 3 subgroups 5 rats each: Subgroup IIA: rats were left without intervention, Subgroup IIB: rats received 0.5 ml distilled water (DW) orally by gastric tube once daily for 4 weeks and Subgroup IIC: rats received collagen peptides orally by gastric tube in the form of powder dissolved in DW at a dose of 2.5 g/kg once daily for 4 weeks.

Results
H&E-stained sections of Subgroups IIA & IIB revealed an apparent decrease in epidermal thickness and disorganized collagen fibers in the dermis. Masson`s Trichrome & orcin stained sections showed apparent decrease in collagen and elastic fibres density and disorganized arrangement. Transmission electron microscopy showed perinuclear vacuolations in keratinocytes and wide separation between them. On the other hand, the structure of skin in Subgroup IIC showed significant improvement in all parameters.

Conclusion
The study showed that collagen hydrolysate can help in improvement of age-related skin changes.