bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enterprise Crowdsourcing Innovation in the Big 4 Consulting Firms
Authors: O'Leary Daniel E. 
Published: April 2019

ABSTRACT
This paper investigates the use of crowdsourcing for innovation in the Big 4 consulting firms and Wikistrat. Information about each of the five firms' is captured in a case study developed for comparison purposes. Those cases are used to examine emerging intra-enterprise characteristics, to analyze some of the key emerging dimensions, and to begin to understand some of the primary concerns and research issues regarding crowdsourcing in consulting. This paper focuses both on internal enterprise use and issues related to developing crowdsourcing for others as part of advisory activities.
Perceval S Sutureless Prosthesis in Aortic Valve Replacement
Authors: Sokolov V. V. , Kovalyov A. I. , Vladimirov V. V. , Ivanov I. V. , Bikbova N. M. 
Published: April 2019

BACKGROUND In 12–47% of patients, there is a need to repeat the aortic valve replacement due to various valve-related complications in the immediate and late postoperative period. The standard operation of repeated aortic valve replacement is a complex procedure and it is associated with an increased risk due to adhesions in the pericardial cavity, previously performed coronary bybass surgery, diffculties of excision of the previously implanted prosthesis, narrow fbrous aortic valve ring and aorta. In 2007, the sutureless Perceval S aortic valve bioprosthesis (Sorin Group, Italy) was introduced into clinical practice. One of the advantages of such a prosthesis is the convenience of its anatomical positioning during repeated operations and the absence of the need to fx the prosthesis with sutures. The aim of study was to summarize the experience of sutureless implantation of the aortic valve prosthesis during repeated replacement.MATERIAL AND METHODS We report the results of treatment in 3 patients with valve-associated complications, who underwent aortic valve repeated replacement with the Perceval S sutureless prosthesis.RESULTS There were no hospital mortality and paraprosthetic regurgitation in the repeated replacement of the aortic valve with the Perceval S sutureless prosthesis. Two patients required implantation of a permanent pacemaker due to the development of a complete atrioventricular block, which was not related to the model of the prosthesis used.CONCLUSION The use of aortic valve prosthesis in cardiac surgery, which does not require fxation with sutures, allows non-standard decisions to be made in the surgical treatment of patients with various complications of previously performed aortic valve replacement and provides good immediate results if repeated replacement is necessary.
From influenza infection to anti-ADAMTS13 autoantibodies via cross-reactivity
Authors: Kanduc Darja 
Published: April 2019

AbstractAutoantibodies (AAbs) against von Willebrand factor (vWF)-cleaving protease ADAMTS13 causally relate to thrombotic thrombocytopenic purpura (TTP). How anti-ADAMTS13 AAbs are generated is unknown. Starting from reports according to which influenza infection can trigger TTP by the production of ADAMTS13 AAbs, this study explores influenza viruses and ADAMTS13 protein for common peptide sequences that might underlie anti-influenza immune responses able to cross-react with ADAMTS13. Results document that numerous peptides are shared between influenza A and B viruses and ADAMTS13, thus supporting the hypothesis of cross-reactivity as a mechanism driving the generation of anti-ADAMTS13 AAbs.
Health Literacy Knowledge and Experiences of Nursing Students at a South African University
Authors: Mibei Francisca , Daniels Felicity 
Published: April 2019

A worldwide high prevalence of low health literacy has been reported, and despite the emergence of health literacy as a better determinant of health than socio-economic status, it is alarming that little attention is being accorded to training health workers on health literacy practices. This study thus sought to describe the health literacy knowledge and experiences of nursing students gained during training in order to establish a basis that will inform future health literacy training. A descriptive cross-sectional survey was carried out using a questionnaire to establish the health literacy knowledge and experience of 82 nursing students. Data were analysed using descriptive as well as inferential statistics. The students exhibited unsatisfactory health literacy knowledge as measured by the questionnaire, with an average score of 73Â per cent, with knowledge gaps in some areasÂ â€“ for example with regard to the effect of low health literacy on patient health outcomes and identification of patients with low health literacy. Their health literacy experience was also lacking, with students only reporting some experience in the use of written materials in providing patient education. The results portray that the emphasis of health literacy in the curriculum failed to have a sufficient effect on health literacy knowledge.
Kemampuan Koneksi Matematis Siswa SMP dalam Menyelesaikan Soal Cerita: Studi Kasus di SMP Negeri 3 Cibadak
Authors: Aspuri Aspuri 
Published: April 2019

<em>Penelitian ini bertujuan untuk mengetahui kemampuan koneksi matematis siswa dalam menyelesaikan soal cerita, khususnya pada materi Kesebangunan. Penelitian ini merupakan jenis penelitian deskriptif dengan pendekatan kualitatif. Subjek penelitiannya yaitu siswa kelas IX SMP Negeri 3 Cibadak yang terdiri atas 25 siswa. Instrumen yang digunakan diantaranya yaitu tes kemampuan koneksi matematis, wawancara dan dokumentasi. Berdasarkan hasil penelitian diperoleh bahwa kemampuan koneksi matematis siswa dalam menyelesaikan soal cerita masih rendah. Hal ini terbukti dari Persentase kemampuan koneksi matematis tiap indikator koneksi kemampuan siswa dalam menuliskan model matematis hanya 48%, kemampuan menghubungkan konsep 60% dan melakukan koneksi prosedur 40%. Dari hasil tes terlihat bahwa kesulitan koneksi matematis siswa belum mampu menggunakan semua informasi dari masalah yang ada dalam soal cerita, belum mampu membuat model matematis dari permasalahan yang dimunculkan dalam soal, sehingga terjadi kesalahan dalam menghubungkan dengan koneksi konsep dan prosedur. Akibatnya, diperoleh jawaban yang tidak relevan. Hendaknya guru dalam proses pembelajaran memfasilitasi siswa untuk mengembangkan kemampuan koneksi matematis siswa dalam menyelesaikan masalah soal cerita</em>.
A EDUCAÇÃO NO CAPÍTULO 9 DO APÊNDICE DA ÉTICA IV DE ESPINOSA
Authors: Oliveira Fernando Bonadia de 
Published: April 2019

No capítulo 9 do apêndice da parte IV da Ética Espinosa afirma que os homens conduzidos pela razão dão elevada demonstração de engenho e arte quando se esforçam por educar os demais para que vivam também sob o império da própria razão. O objetivo desse artigo é interpretar esse capítulo, apresentando as relações que ele estabelece com o conjunto das obras espinosanas.
EDUCAÇÃO, CONHECIMENTO E FINITUDE
Authors: Seibt Cezar Luís 
Published: April 2019

A complexidade da realidade humana não permite que a razão instrumental esgote explicativamente os elementos que compõe a realidade educacional. Surge a necessidade de uma atitude aberta e atenta para compreender aquilo que se recusa e esconde na cotidianidade. A fenomenologia hermenêutica é consciência dos limites da racionalidade, postura vigilante, um desafio para a responsabilidade e criatividade na atividade pedagógica.
ELEMENTOS PARA UMA FILOSOFIA DA EDUCAÇÃO HEIDEGGERIANA HOMEM E MUNDO NA PERSPECTIVA FENOMENOLÓGICO-EXISTENCIAL
Authors: Ferreira Jr. Wanderley J. 
Published: April 2019

O trabalho toma como referências básicas os novos significados das noções de homem, mundo e cuidado na obra Ser e Tempo (1927) do filósofo alemão Martin Heidegger. Procura-se apontar as possíveis repercussões de tais noções no âmbito da educação e em que medida Ser e Tempo poderia oferecer elementos e subsídios teóricos para o estabelecimento de uma filosofia da educação na perspectiva fenomenológico-existencial. Ao mesmo tempo procura-se determinar seus limites e possibilidades na construção de uma nova percepção do fenômeno da educação e de um novo significado para o ato de educar.
Medical Tourism: Its Role in Maintaining Health and Increasing Life Expectancy
Authors: Molchanov I. N. 
Published: April 2019

The subject of the research is development of medical tourism as a measure of maintaining health and increasing life expectancy of the population. The relevance of the study is substantiated by decisions on increasing the retirement age, which requires improving working conditions and arrangement of high-performance jobs as components of the social policy aimed at increasing life expectancy and improving the quality of life as the most important conditions for ensuring sustainable economic development of the country. The purpose of the research was to determine the role of medical tourism in maintaining physical strength, increasing the lifetime and maintaining the health of the population in line with the key national goal of accelerating the national economy growth rates. Based on official statistical and audit information and expert opinions, the paper discusses specific features and practices of organizing medical tourism, analyzes the current state and identifies factors that have a multidirectional impact on its development. It is concluded that the necessity to take into account the specific conditions of the spatial development strategy of the Russian Federation orients companies engaged in medical tourism towards expanding the range and improving the quality of services provided. The proposed measures aimed at perfection of the methodological principles and tools of research can be used at the regional level to justify the creation of tourist clusters. Proposals for the development of marketing are aimed at improving the financial sustainability of companies and recommended for taking into account by the top management of medical tourism companies.
The World Economic Forum in Davos: Poverty and Inequality of Income Distribution as Evil Phenomena of Modern World Development
Authors: Perskaya V. V. 
Published: April 2019

The subject of the research is the opinions of the expert community expressed during panel discussions at the World Economic Forum held in Davos in 2019 related to ways of eliminating poverty and disproportionality of income distribution in the world. The purpose of the research was to confirm the permanent commitment of the WEF expert community to the concept of neoliberalism, despite the fact that it was neoliberal values that exacerbated the development of poverty and disproportionality in income distribution as trends in the current global development. The research also proved the utopian nature of their recommendations for overcoming the negative phenomena. The position of the expert community at the World Economic Forum was reduced solely to the concept of the neoliberal mainstream — reducing the role of state regulation, establishment of global governance for a multilateral social contract at the level of an international organization capable of eliminating social inequality and income disproportionality in the world economy. Particular attention was paid to the lack of social elevators in developed and developing countries contributing to the poverty aggravation among the population. The documents of some international organizations indicate the need to intensify national state policies in the field of social support and social security. The paper discusses various aspects of national state policies in a number of countries aiming to gradually smooth out the level of social security of citizens along with supporting the middle class as the basis for stable development. For the first time, the problem of enhancing the role of non-profit public organizations in overcoming the income disproportionality and eliminating extreme poverty and destitution, especially in developing countries, was addressed at the level of interstate discussion. However, involving the poor in the work of these organizations seems to be challenging because the sources for funding their activities are not defined. It is concluded that globalization is the determining trend in the development of the world economy; the basic problems of globalization include poverty and disproportionality of income distribution both at the inter- and intracountry levels; there is a possibility of concluding a public multilateral agreement accumulating measures taken at the supranational level. The living conditions of the middle class are deteriorating, their incomes are decreasing. The USA policy “Make America great again” is aimed at raising the living standards of the middle class, i.e. the idea of the problem solution on the multinational basis is being rejected; the access to education, formation of social elevators, including those for young people, establishment of social protection systems, etc. are still beyond the attention of national governments in developed countries.
Prosumers’ Engagement in Business Process Innovation – The Case of Poland and the UK
Authors: Wanda Ziemba Ewa , Eisenbardt Monika , Mullins Roisin , Dettmer Sandra 
Published: April 2019

Aim/Purpose: The main purpose of this paper is to identify prosumers’ engagement in business process innovation through knowledge sharing.

Background: In the increasingly competitive knowledge-based economy, companies must seek innovative methods of doing business, quickly react to consumer demand, and provide superior value to consumers. Simultaneously, contemporary consumers, named “prosumers”, want to be active co-creators of value and satisfy their consumption needs through collaboration with companies for co-creation, co-design, co-production, co-promotion, co-pricing, co-distribution, co-consumption, and co-maintenance. Consequently, consumer involvement in development and improvement of products and business process must be widely analyzed in various contexts.

Methodology: The research is a questionnaire survey study of 388 prosumers in Poland and 76 in the UK.
Contribution	The contribution of this research is twofold. First, it identifies how prosumers can be engaged in business processes through knowledge sharing. Second, it investigates the differences between Poland- and UK-based prosumers in engagement in business process.

Findings: The study found that prosumers are engaged in knowledge sharing at each stage of the business process innovation framework. However, there are differences in the types of processes that draw on prosumers’ engagement. Prosumers in Poland are found to engage mostly in the business process of developing and managing products, whereas prosumers in the UK engage mostly in the business process of managing customer services.

Recommendations for Practitioners: This study provides practitioners with guidelines for engaging prosumers and their knowledge sharing to improve process innovation. Companies gain new insight from these findings about prosumers’ knowledge sharing for process innovation, which may help them make better decisions about which projects and activities they can engage with prosumers for future knowledge sharing and creating prospective innovations.

Recommendations for Researchers: Researchers may use this methodology and do similar analysis with different samples in Poland, the UK, and other countries, for many additional comparisons between different groups and countries. Moreover, a different methodology may be used for identifying prosumers’ engagement and knowledge sharing for processes improvement.

Future Research: This study examined prosumers’ engagement from the prosumers’ standpoint. Therefore prosumers’ engagement from the company perspective should be explored in future research.
EFFECT OF PROPRANOLOL ON AEROBIC-HEMODYNAMIC SUPPORT OF PHYSICAL ACTIVITY IN PATIENTS WITH EFFORT ANGINA, POSITIVE ANTIANGINAL ACTION AND THE ABSENCE OF CLINICAL EFFECT AFTER PROPRANOLOL-BASED TREATMENT
Authors: Vasilyev A. P. , Streltsova N. N. 
Published: April 2019

Aim. To analyze the changes in the aerobic-hemodynamic parameters during physical exercise in patients with effort angina administered with reference non-selective beta-blocker propranolol (Obsidan) with positive antianginal action and the absence of clinical effect after the drug intake.Material and Methods. A total of 58 patients (mean age of 54.2 [48.5; 59.5] years) with effort angina of functional class II–IV were examined with spiro-veloergometry tests before and after administration of propranolol (Obsidan: manufactured by Isis Pharma GmbH, Germany) at a dose of 40 mg. At threshold physical activity the following parameters were assessed: oxygen consumption (VO2 ), specific oxygen consumption, cardiac index (CI), rate pressure product (RPP); total peripheral vascular resistance (TPVR), arteriovenous oxygen difference (a-vDО2 ) and mechanical work of the heart (HW).Results. The efficacy of single-dose obsidian was observed in 58.6% of patients with angina (group 1); in this, tolerance to physical exercise increased from 50.0 [25.0; 75.0] W to 75.0 [50.0; 100.0] W. In the rest of patients (group 2), no antianginal effect was registered. At the first stage (at initial threshold physical activity level), administration of propranolol was characterized by saving pattern of heart function: statistically significant decrease in the heart rate, mean arterial pressure, CI and HW. This naturally resulted in reduction of myocardial oxygen demand (decrease in RPP from 163.0 [134.5; 218.5] U to 102.0 [90.0; 142.5] U; p<0.001) and predetermined the drug anti-ischemic action. At the second stage (maximum physical effort), an increase in the physical activity, caused by increase in VO2 from 738.0 [604.5; 1148.0] mL/min to 972.0 [774.5; 1458.0] mL/min, occurred due to higher oxygen extraction from peripheral blood (a-vDО2 increase; p<0.002). In group 2, despite the absence of an increase in tolerance to physical exercise, administration of propranolol was characterized by low RPP threshold i.e. the physical effort similar to the initial level was performed at a lower cardiac energy consumption.Conclusion. Therefore, anti-ischemic effect of Obsidan was due to a decrease in theenergy expenditure of the cardiac function along with a limitation in the hemodynamic productivity efficiently compensated by an increase in the oxygen extraction from circulating blood during physical activity.
PLATELETS, ASPARTATE AMINOTRANSFERASE, TUMOR NECROSIS FACTOR-α: LABORATORY PANEL FOR DIAGNOSIS OF LIVER FIBROSIS STAGE
Authors: Shchekotova A. P. , Bulatova I. A. , Sosnin D. Yu. , Tretyakova Yu. I. 
Published: April 2019

Aim. To study significance of platelet count and values of aspartate aminotransferase and tumor necrosis factor-α in the evaluation of the severity of liver fibrosis in chronic hepatitis C and for the development of fibrosis index calculation formula.Material and Methods. The study included 70 patients with chronic hepatitis C end 30 healthy persons. Liver density was estimated by ultrasound elastography.Results. The correlation analysis revealed strong relationships between the ultrasound elastography findings of fibrosis stage and the platelet count (r=0.83), aspartate aminotransferase (r=0.83), and tumor necrosis factor-α (r=0.81). The optimal separation points of laboratory tests for fibrosis exclusion were identified as follows: platelet count>270×109 /L (test sensitivity=96.2%), aspartate aminotransferase level<44 E/L (sensitivity=96.2%), and tumor necrosis factor-α concentration below 1.9 pg/mL (sensitivity=92.3%). The obtained values of laboratory parameters were used for calculation of the liver fibrosis index. The value of the fibrosis index ranging between 0 and 0.5 indicated the absence of fibrosis (stage F0), the value of the fibrosis index ranging between 0.6 and 2.5 corresponded to the moderate stage of fibrosis (F1-2), and the value of the fibrosis index>2.5 corresponded to the severe fibrosis/cirrhosis of the liver (F3-4) with diagnostic sensitivity of 83% and specificity of 78%.Conclusion. Platelet count, the values of aspartate aminotransferase and tumor necrosis factor-α levels, fibrosis index, and laboratory test data can be used for ruling out fibrosis in chronic hepatitis C patients as well as for stratification of liver fibrosis stages.
VENOUS CONDUITS IN CORONARY SURGERY: OLD PROBLEMS — NEW SOLUTIONS
Authors: Vecherskiy Y. Y. , Manvelyan D. V. , Zatolokin V. V. , Shipulin V. M. 
Published: April 2019

The introduction of autovenous coronary artery bypass grafting (CABG) marked the era of surgical revascularization in patients with coronary artery disease. It provided effective treatment for angina and significantly improved the long-term prognosis. Venous transplants today remain the most popular conduits in coronary surgery due to their availability, ease of harvesting, and the absence of length restrictions. Despite the advantages of autovenous CABG, the main disadvantage is the high incidence of venous graft failure, which represents an important and unresolved problem in cardiac and cardiovascular surgery. On the other hand, the traditional allocation of a large saphenous vein implies the dissection of soft tissues throughout the length of the isolated conduit. Traumatic dissection causes a long-lasting persistent pain syndrome after surgery, frequent abnormalities in skin sensitivity, and a high incidence of wound complications in the lower extremities. These complications lengthen the period of rehabilitation of patients and worsen the quality of life. There is an approach of isolating the vein in a block with surrounding tissues to optimize the long-term functioning of the venous shunt, however, this technique is even more traumatic than the traditional method, and therefore its use is limited in practice. On the other hand, the introduction of minimally invasive methods of isolation allowed to reduce the incidence of wound complications and to improve the cosmetic result, but there is no convincing data regarding the effect on the consistency of shunts in the long-term postoperative period. The problems associated with the use of venous conduits in CABG are multifaceted, and their solutions are necessary to improve the effectiveness of surgical revascularization.