bluuebunny/crossref_metadata_2025_split huggingface dataset:
Information and volatility linkages across energy and financial markets
Authors: Ding Ashley 
Published: July 2019

This study examines information and volatility linkages across energy and financial markets. In a world economy so connected, the impacts of climate change are likely to be transmitted through interlinked global markets. Hence, uncovering and understanding the interaction across these markets is a fundamental concern during the energy transition as it helps to understand how to strengthen incentives to facilitate energy investments. Based on the relation between information flows and volatility, this study employs a simple correlation approach based on implied volatility measures and the trading model of Fleming et al. to measure the common information linkages, as gauged by the correlation of return volatilities. The results suggest that volatility linkages across these markets are strong due to common information sharing and cross-market hedging. JEL Classification: G12, G14
Key elements of interventions for heart failure patients with mild cognitive impairment or dementia: A systematic review
Authors: Hickman Louise , Ferguson Caleb , Davidson Patricia M , Allida Sabine , Inglis Sally , Parker Deborah , Agar Meera 
Published: July 2019

Background: The purpose of this systematic review was to (a) examine the effects of interventions delivered by a heart failure professional for mild cognitive impairment and dementia on cognitive function, memory, working memory, instrumental activities of daily living, heart failure knowledge, self-care, quality of life and depression; and (b) identify the successful elements of these strategies for heart failure patients with mild cognitive impairment or dementia. Methods and results: During March 2018, an electronic search of databases including CINAHL, MEDLINE, EMBASE and PsycINFO was conducted. All randomised controlled trials, which examined an intervention strategy to help heart failure patients with mild cognitive impairment or dementia cope with self-care, were included. An initial search yielded 1622 citations, six studies were included ( N= 595 participants, mean age 68 years). There were no significant improvements in cognitive function and depression. However, significant improvements were seen in memory ( p=0.015), working memory ( p=0.029) and instrumental activities of daily living ( p=0.006). Nurse led interventions improved the patient’s heart failure knowledge ( p=0.001), self-care ( p<0.05) and quality of life ( p=0.029). Key elements of these interventions include brain exercises, for example, syllable stacks, individualised assessment and customised education, personalised self-care schedule development, interactive problem-solving training on scenarios and association techniques to prompt self-care activities. Conclusions: Modest evidence for nurse led interventions among heart failure patients with mild cognitive impairment or dementia was identified. These results must be interpreted with caution in light of the limited number of available included studies.
A Systematic Review and Meta-Analysis of del Nido Versus Conventional Cardioplegia in Adult Cardiac Surgery
Authors: An Kevin R. , Rahman Ishtiaq A. , Tam Derrick Y. , Ad Niv , Verma Subodh , Fremes Stephen E. , Latter David A. , Yanagawa Bobby 
Published: July 2019

Objective Del Nido cardioplegia (DC) has been used extensively in pediatric cardiac surgery but the efficacy and safety in adults remains uncertain. Our objective was to perform a systematic review and meta-analysis comparing DC and blood cardioplegia (BC) in our primary endpoint of 30-day or in-hospital mortality as well as other efficacy and safety endpoints. Methods Both MEDLINE and EMBASE were searched from 1996 to 2017 for studies comparing DC and BC. Data were extracted by 2 independent investigators and aggregated in a random effects model. Results One randomized controlled trial ( n = 89), 7 adjusted ( n = 1,104), and 5 unadjusted observational studies ( n = 717) were included. There was no difference in in-hospital mortality between DC and BC (relative risk:0.67, 95% confidence interval [CI]: 0.22, 2.07; P = 0.49). DC reduced cardioplegia volume requirements (mean difference [MD]:−1.1 L, 95% CI, −1.6, −0.6; P < 0.0001), aortic cross-clamp time (MD: −8 minutes, 95% CI, −12, −3; P = 0.0004), and cardiopulmonary bypass (CPB) times (MD: −8 minutes, 95% CI, −14, −3; P = 0.03). DC reduced troponin release (standardized MD: −0.3, 95% CI, −0.5, −0.1; P = 0.001). In-hospital outcomes of stroke, atrial fibrillation, acute kidney injury/dialysis, low cardiac output state, blood transfusion, reoperation rate, postoperative left ventricular EF, intensive care unit length of stay (LOS), and in-hospital LOS were comparable between groups. Conclusions DC is a safe alternative to BC in routine adult cardiac surgery. Its use is associated with reduction in CPB and aortic cross-clamp times and may potentially offer improved myocardial protection.
Pulmonary arterial hypertension in interferonophaties: a case report and a review of the literature
Authors: Trombetta A. , Ghirardo S. , Pastore S. , Tesser A. , Piscianz E. , Tommasini A. , Bobbo M. , Taddio A. 
Published: July 2019

BackgroundPulmonary arterial hypertension consists in an increase of mean pulmonary arterial pressure (PAPm ≥ 25 mmHg), and may lead to right ventricular failure. Pulmonary arterial hypertension can arise in several disorders, encompassing inflammatory conditions and connective tissue diseases. The occurrence of pulmonary arterial hypertension has recently been reported in monogenic interferonopathies and in systemic lupus erythematosus, highlighting the pathogenic role of type I interferons and paving the way to therapies aimed at inhibiting interferon signaling.CaseWe describe a 17‐year‐old boy with DNase II deficiency, presenting a clinical picture with significant overlap with systemic lupus erythematosus. During treatment with the Janus kinase inhibitor ruxolitinib, he developed pulmonary arterial hypertension, raising the question whether it could represent a sign of insufficient disease control or a drug‐related adverse event. The disease even worsened after drug withdrawal, but rapidly improved after starting the drug again at higher dosage.Summary and conclusionPulmonary arterial hypertension can complicate type I interferonopathies. We propose that ruxolitinib was beneficial in this case, but the wider role of Janus kinase inhibitors for the treatment of pulmonary arterial hypertension is not clear. For this reason, a strict cardiologic evaluation must be part of the standard care of subjects with interferonopathies, especially when Janus kinase inhibitors are prescribed.
The “amphi”-brains of amphipods: new insights from the neuroanatomy of Parhyale hawaiensis (Dana, 1853)
Authors: Wittfoth Christin , Harzsch Steffen , Wolff Carsten , Sombke Andy 
Published: July 2019

AbstractBackgroundOver the last years, the amphipod crustaceanParhyale hawaiensishas developed into an attractive marine animal model for evolutionary developmental studies that offers several advantages over existing experimental organisms. It is easy to rear in laboratory conditions with embryos available year-round and amenable to numerous kinds of embryological and functional genetic manipulations. However, beyond these developmental and genetic analyses, research on the architecture of its nervous system is fragmentary. In order to provide a first neuroanatomical atlas of the brain, we investigatedP. hawaiensisusing immunohistochemical labelings combined with laser-scanning microscopy, X-ray microcomputed tomography, histological sectioning and 3D reconstructions.ResultsAs in most amphipod crustaceans, the brain is dorsally bent out of the body axis with downward oriented lateral hemispheres of the protocerebrum. It comprises almost all prominent neuropils that are part of the suggested ground pattern of malacostracan crustaceans (except the lobula plate and projection neuron tract neuropil). Beyond a general uniformity of these neuropils, the brain ofP. hawaiensisis characterized by an elaborated central complex and a modified lamina (first order visual neuropil), which displays a chambered appearance. In the light of a recent analysis on photoreceptor projections inP. hawaiensis, the observed architecture of the lamina corresponds to specialized photoreceptor terminals. Furthermore, in contrast to previous descriptions of amphipod brains, we suggest the presence of a poorly differentiated hemiellipsoid body and an inner chiasm and critically discuss these aspects.ConclusionsDespite a general uniformity of amphipod brains, there is also a certain degree of variability in architecture and size of different neuropils, reflecting various ecologies and life styles of different species. In contrast to other amphipods, the brain ofP. hawaiensisdoes not display any striking modifications or bias towards processing one particular sensory modality. Thus, we conclude that this brain represents a common type of an amphipod brain. Considering various established protocols for analyzing and manipulatingP. hawaiensis, this organism is a suitable model to gain deeper understanding of brain anatomy e.g. by using connectome approaches, and this study can serve as first solid basis for following studies.
Serbian reflective citizens and the art of psychosocial listening and dialogue at the caesura
Authors: Mojović Marina 
Published: July 2019

‘Serbian reflective citizens’ is a psychosocial community practice and a new discipline conceived in Belgrade amidst Yugoslavia’s ‘Horrible Nineties’ by Dr Marina Mojović (the author) and Dr Jelica Satarić, both psychiatrists and psychotherapists in various Yugoslav public health psychiatric institutions. The therapeutic communities seemed to open a way for new paradigms to shed light and hope on overwhelming social despair, however, besides the Belgrade therapeutic community, ‘Serbian reflective citizens’ has a multitude of roots and ancestors in professional and wider social communities.
The author explains the development of ‘Serbian reflective citizens’ using a metaphor of caesura at birth, discussing the history and methodology, its grassroots style, numerous ancestors, ways (and spaces) of being, its building blocks, names and other identity aspects of this new community practice and discipline, with particular mention of a recent example of a newly-formed reflective citizens branch in Italy. The mentioned caesura of birth is also considered by the author as a transitional space, a place where, as Marina Abramović would say, ‘The artist is present’. The Northfield experiments are seen as transcending the caesura and, as such, particularly mentioned at the 2nd International Belgrade Conference on Reflective Citizens in 2014, ‘Learning through Experience about Inclusion/Exclusion Phenomena in and between Traditions of Bion, Foulkes and Main’.
A Política de AIDS no Brasil: uma abordagem histórica
Authors: Souza Bruna Bezerra , Vasconcelos Carla Calado , Tenório Danielle de Melo , Alves Lucena Maria Gorethe , Holanda Reila Leliana Tenório de 
Published: July 2019

Uma política pública expressa o conjunto das diretrizes e referenciais ético-legais adotadas pelo Estado para fazer frente a um problema e/ou a uma demanda que a sociedade lhe apresenta. Cabe ao Estado definir seu caráter, suas responsabilidades, seu plano de ação e programas, a fim de buscar o equacionamento dessa demanda. Diante deste contexto, a construção da política de AIDS no Brasil foi originada da luta dos movimentos sociais e da sociedade civil organizada, devido ao reconhecimento da extensão e da magnitude da epidemia.
Impacto da saúde bucal na concessão de auxílios-doença junto ao Instituto Nacional de Seguridade Social (INSS)
Authors: Bomfim Rafael Aiello , Mazzilli Luiz Eugênio Nigro 
Published: July 2019

A pesquisa investigou o impacto da saúde bucal na concessão de auxílios-doença previdenciários e acidentários concedidos pelo INSS. A amostra foi extraída do banco de dados públicos do Ministério da Previdência Social e compreendeu o período de janeiro a dezembro de 2011. Foram recuperados todos os registros correspondentes ao intervalo CID 10 (K00 e K14) e (C00 a C14) em sua codificação de 3 caracteres. Os resultados mostraram que foram concedidos 1565 benefícios (auxílios doença previdenciários) no intervalo K00 a K14 (intervalo este referente às doenças da cavidade oral, das glândulas salivares e dos maxilares), e que no intervalo C00 e C14, (referente às neoplasias malignas da cavidade bucal e orofaringe) foram concedidos 3039 auxílios. Em relação aos auxílios doença acidentários, o intervalo CID K00 a K14 gerou 12 auxílios e o intervalo C00 a C14 gerou apenas 3 auxílios. Os cuidados em relação à saúde bucal dentro do meio ambiente laboral merecem especial atenção, visto que estes auxílios oneraram aproximadamente em cerca de 33 milhões de reais ao INSS em 2011, o que poderia ser diminuido se ações voltadas à prevenção e promoção da saúde bucal dos trabalhadores fossem conduzidas por equipes permanentes em saúde bucal dentro do Serviço de Engenharia de Segurança e Medicina do Trabalho (SESMT) das empresas, bem como a incorporação de equipes odontológicas dentro dos Centros de Referência em Saúde do Trabalhador (CEREST).
Pré-natal odontológico: noções de interesse
Authors: Moreira Marília Rodrigues , Santin Gabriela Cristina , Matos Leonardo Gontijo , Gravina Danuze Batista Lamas , Faquim Juliana Pereira da Silva 
Published: July 2019

Apesar dos avanços na Odontologia, muitos cirurgiões dentistas ainda possuem a concepção de que o tratamento odontológico à gestante deve ser postergado e que procedimentos como tomadas radiográficas e anestesias não devem ser realizados. Entretanto sabe-se que nesse período a gestante constitui um grupo de risco uma vez que as mudanças hormonais, físicas e psicológicas podem desencadear um desequilíbrio à saúde bucal da mulher. Dessa forma, o objetivo desta revisão de literatura foi esclarecer e atualizar as recomendações sobre o pré-natal odontológico. A literatura científica mostra que o atendimento odontológico as gestantes é seguro e que apresenta muitos benefícios, tanto para a mãe quanto para o próprio bebê.
Revisão integrativa: a acupuntura no tratamento da ansiedade e estresse em mulheres com câncer de mama
Authors: Novaes Ana Rita Vieira de , Brandão-Souza Camila , Zndonade Eliana , Amorim Maria Helena Costa 
Published: July 2019

O câncer de mama é um grave problema de saúde pública, o segundo tipo mais prevalente entre as mulheres e responde por 28,1% das neoplasias. A busca pelas Práticas Integrativas e Complementares tem aumentado em diversas regiões, e a acupuntura é uma das práticas mais utilizadas da MTC, inclusive na oncologia, com vistas a tratar sintomas do câncer ou dos efeitos adversos do tratamento oncológico. Entre as queixas, encontram-se a ansiedade e o estresse, que causam grandes transtornos. Esta revisão integrativa buscou conhecer, na literatura, informações sobre a aplicação da acupuntura na ansiedade e no estresse de mulheres com câncer de mama. Realizou-se a busca entre julho e novembro de 2015 nas bases de dados da LILACS, MEDLINE, PsycINFO e banco de teses da CAPES, utilizando descritores apropriados. Foram identificados 6 estudos; sendo 3 transversais, 1 descritivo, 1 de coorte transversal e 1 caso controle de base populacional. Os artigos demonstraram a efetividade da acupuntura no tratamento do estresse e da ansiedade no câncer de mama no período per-operatório e durante a quimioterapia. A prevalência do uso da MTC concomitante ao tratamento ocidental é alta, embora a acupuntura seja pouco usada. A desinformação entre os profissionais de saúde ainda perdura e precisa ser mais bem compreendida. Estudar a efetividade em todas as etapas do tratamento oncológico e que avaliem as taxas de recidiva e sobrevida de usuários da acupuntura associada ao tratamento oncológico é indicada.
A Brief History of the Yield Stress
Authors: Barnes Howard A. 
Published: July 2019

Abstract
This short article is a summary of a recently published, lengthy review [1] in which the author challenges the often-accepted view that materials have yield stresses, below which no flow takes place. However, following the introduction of the new generation of controlled-stress rheometers it is shown that when careful measurements are made below the supposed ’yield stress‘, flow does actually take place. The argument for the nonexistence of the yield stress as a physical entity now seems insuperable. However, in spite of this, it is nevertheless accepted that an apparent yield stress is a useful mathematical abbreviated description of limited data over a given range of flow conditions. This yield stress parameter can be used effectively for predicting flow, but only within the region of the original measurement that furnished the yield stress.
A protocol for testing the stability of biochemical analytes. Technical document
Authors: Gómez-Rioja Rubén , Segovia Amaro Marta , Diaz-Garzón Jorge , Bauçà Josep Miquel , Martínez Espartosa Débora , Fernández-Calle Pilar 
Published: July 2019

Abstract
Stability of a measurand in a specimen is a function of the property variation over time in specific storage conditions, which can be expressed as a stability equation, and is usually simplified to stability limits (SLs). Stability studies show differences or even inconsistent results due to the lack of standardized experimental designs and heterogeneity of the chosen specifications. Although guidelines for the validation of sample collection tubes have been published recently, the measurand stability evaluation is not addressed. This document provides an easy guideline for the development of a stability test protocol based on a two-step process. A preliminary test is proposed to evaluate the stability under laboratory habitual conditions. The loss of stability is assessed by comparing measurement values of two samples obtained from the same patient and analyzed at different time points. One of them is analyzed under optimal conditions (basal sample). The other is stored under specific stability conditions for a time set by the laboratory (test sample). Differences are expressed using percentage deviation (PD%) to facilitate comparison with specifications. When the preliminary test demonstrates instability, a comprehensive test is proposed in order to define the stability equation and to specify SLs. Several samples are collected from a set of patients. The basal sample is analyzed under optimal conditions, whereas analysis of test samples is delayed at time intervals. For each patient PD% is calculated as the difference between measurements for every test sample and its basal one and represented in a coordinate graph versus time.
An ethical framework for counseling about mode of delivery for desired psychosocial benefit in pregnancies complicated by severe fetal anomalies
Authors: Nguyen Michelle T. , McCullough Laurence B. , Chervenak Frank A. , Shaw Kathryn J. , Luckey Dominique 
Published: July 2019

Abstract

Background
A fetal diagnosis poses ethical challenges when a woman requests elective cesarean delivery for psychosocial reasons. We address the ethical challenges of counseling such patients.

Case presentation
A 36-year-old G4P2012 has chosen to continue a pregnancy despite a high likelihood of trisomy 18. At 36.5 weeks she was admitted for preeclampsia with severe features and requested to be delivered by primary cesarean section. Due to the poor prognosis associated with trisomy 18, the patient’s request for cesarean delivery was declined even when her baby changed to breech presentation with Category 2 fetal heart rate (FHT). The patient subsequently experienced a traumatic stillbirth and post-traumatic shock disorder (PTSD).

Conclusion
The obstetrician’s goal should be to transform the patient’s request into an informed decision. The obstetrician should explain that, while a cesarean could increase the likelihood of a live birth, it will not alter long-term neonatal outcomes and entails net biomedical risk for the current and future pregnancies. The obstetrician should ensure that the patient understands these clinical realities. The obstetrician should support the patient’s decision-making about whether to accept the risks of cesarean delivery for psychosocial benefit. The obstetrician should initiate counseling during prenatal visits to empower the patient with information to meaningfully exercise her autonomy. If the patient makes an informed decision for cesarean delivery, it becomes ethically permissible. Plans regarding intrapartum management and mode of delivery should be documented in case the patient is delivered by a physician who was not involved in prenatal counseling.
A Method to Solve the Reaction-Diffusion-Chemotaxis System
Authors: Hwang Yao-Hsin , Yu Jui-Ling , Hu Chin-Kun 
Published: July 2019

Abstract
The objective of this article is to use a recent developed scheme to simulate reaction-diffusion-chemotaxis equations. The solution gradient required for an accurate discretization is computed directly as an additional variable rather than interpolated from solution values around neighboring computational nodes. To achieve this goal, a supplementary equation and its associated control volume are introduced to retain a compact and accurate discretization. Scheme essentials are exposed by the numerical analysis on two-dimensional chemotaxis problems to reveal its formal accuracy. Due to its highly comprehensible and practical features, this formulation can be easily extended to solve problems for other two-dimensional rectangular grid systems. One- and two-dimensional problems are solved to verify its simulation accuracy and to study the possible formation of bacteria bands. We further perform the linearization technique to the reaction term to increase the stability of the current scheme. From the numerical analysis and computational results, it is found that the present formulation is a useful tool to solve reaction-diffusion-chemotaxis equations.
Nephrogenic diabetes insipidus in a 15-year-old Hispanic female with a novel AQP2 mutation
Authors: Long Benjamin C. , Weber Zachary J. , Oberlin John M. , Sutter Deena E. , Berg Janet M. 
Published: July 2019

Abstract
Nephrogenic diabetes insipidus (NDI) is a rare inherited disorder most often caused by mutations in the arginine-vasopressin receptors or aquaporin channels, which subsequently impairs the water reabsorption in the kidney. This case report describes a 15-year-old female diagnosed with NDI after an acute gastroenteritis and multiple fluid boluses leading to intractable emesis. Gene testing reveals our patient is compound heterozygous for novel AQP2 gene mutations with a cytosine-to-thymine substitution at nucleotide position 277 and adenine-to-cytosine substitution at nucleotide position 659. Therefore, we report a novel AQP2 gene mutation in an adolescent patient which is outside the common age for diagnosis.