bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Cohesive Deep Drilling Field Strategy for LSST Cosmology
Authors: Gris Philippe , Awan Humna , Becker Matthew R. , Lin Huan , Gawiser Eric , Jha Saurabh W. ,   The LSST Dark Energy Science Collaboration
Published: November 2024

Abstract
The Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) will image billions of astronomical objects in the wide–fast–deep primary survey and in a set of minisurveys including intensive observations of a group of deep drilling fields (DDFs). The DDFs are a critical piece of three key aspects of the LSST Dark Energy Science Collaboration (DESC) cosmological measurements: they provide a required calibration for photometric redshifts (photo-z) and weak gravitational lensing (WL) measurements and they directly contribute to cosmological constraints from the most distant Type Ia supernovae (SNe Ia). We present a set of cohesive DDF strategies fulfilling science requirements relevant to DESC and following the guidelines of the Survey Cadence Optimization Committee. We propose a method to estimate the observing strategy parameters and we perform simulations of the corresponding surveys. We define a set of metrics for each science case to assess the performance of the proposed observing strategies. We show that the most promising results are achieved with deep rolling surveys characterized by two sets of fields: ultradeep fields (z ≲ 1.1) observed at a high cadence with a large number of visits over a limited number of seasons, and deep fields (z ≲ 0.7), observed with a cadence of ∼3 nights for 10 yr. These encouraging results should be confirmed with realistic simulations using the LSST scheduler. A DDF budget of ∼8.5% is required to design observing strategies satisfying all the cosmological requirements. A lower DDF budget leads to surveys that either do not fulfill the photo-z/WL requirements or are not optimal for SN Ia cosmology.
Long-term Simultaneous Monitoring Observations of SiO and H2O Masers toward the Mira Variable WX Serpentis
Authors: Lim Jang-Ho , Kim Jaeheon , Cho Se-Hyung , Kim Hyosun , Yoon Dong-Hwan , Son Seong-Min , Suh Kyung-Won 
Published: November 2024

Abstract
We present the results from long-term simultaneous monitoring observations of SiO and H2O masers toward the Mira variable star WX Serpentis. This study has been conducted with 21 m single-dish radio telescopes of the Korean VLBI Network from 2009 June to 2021 June. Five maser lines were considered: SiO v = 1, 2, J = 1−0; SiO v = 1, J = 2−1, 3−2; and H2O 61,6–52,3 transitions, with the SiO maser lines distributed near the stellar velocity and the H2O maser exhibiting an asymmetric line profile with five to six peaked components. Intense H2O maser emissions suddenly appeared in 2019 September, indicating flaring. The intensity variations of SiO and H2O masers are strongly correlated with the optical light curve (OLC) of the central star, with individual phase lags; the phase lag of the H2O maser relative to the OLC is larger than that of the SiO masers. The consequent phase difference between the SiO masers and the H2O maser likely indicates that their formation regions and main driving mechanisms are different from each other. The SiO masers in WX Ser exhibit a dominant single-peak velocity distribution, similar to other Mira variable stars. However, the H2O maser displays distinct morphological features, showing a radial acceleration and preferential intensity dominance at blueshifted velocities. This suggests that the H2O maser clouds of WX Ser are moving outward, thereby developing an asymmetric outflow owing to nonuniform material ejection from the stellar atmosphere. The findings confirm that an initial asymmetric outflow structure emerged during the thermally pulsing asymptotic giant branch phase, specifically in the Mira variable star stage.
Exploring the Role of Tools and Technologies in Enhancing Human Knowledge Acquisition: The Flora of Cambodia as a Pilot Project.
Authors: Ung Visotheary 
Published: November 2024

The globalization of the world profoundly impacts the academic and scientific domains. Technological advances have enabled an immeasurable progress in many scientific fields, for example structural or functional genomics, bioinformatics or even the development of artificial intelligence, which is becoming a catalyst for disciplines such as taxonomy. However, we are witnessing an unprecedented paradox. We have entered a period described as the 6th mass extinction (e.g., Ceballos et al. 2015, Ceballos et al. 2020, Cowie et al. 2022), where biodiversity has been in decline for many years because of anthropogenic activity (Myers et al. 2000, Sachs et al. 2009, Butchart et al. 2010) and yet, techniques have never been so advanced (e.g., online databases, metabarcording and eDNA identification methods). They produce a deluge of results and data that must be managed to facilitate their access and re-use and benefit to all users, i.e., scientists and stake-holders or policy makers on a global scale.
Currently, the flora of Cambodia is part of the Flora of Cambodia, Laos and Viêt-nam*1 and is jointly edited by the Royal Botanic Garden of Edinburgh and the Muséum national d’Histoire naturelle in Paris since 2013. Given Cambodia's historical ties to French Indochina, France's long-term presence has significantly contributed to the documentation of Cambodia's biodiversity. The largest collection of Cambodian specimens is housed at the Paris Herbarium.
The Flora of Cambodia project (Ung 2023) started in 2023 as a pilot project for testing the effectiveness of different open tools developped for taxonomists, e.g., the echinopscis platform*2 developped at the Royal Botanical Garden Kew; Bionomia*3; data made available online through platforms such as the Global Biodiversity Information Facility, Atlas of Living Australia, and World Flora Online. Other sources will also be used, like publications (Joyce et al. 2020) and "les herbonautes"*4, a citizen science platform. The short-term result is to produce a checklist of the vascular plants of Cambodia in multiple languages including Khmer. This project aligns with the FAIR (Findable, Accessible, Interoperable, Reusable) (Wilkinson et al. 2016) and CARE (Collective benefit, Authority to control, Responsability, Ethics) (Carroll et al. 2020) principles.
Promising selective alpha-1 blocker silodosin as a new therapeutic strategy for premature ejaculation and its drug adverse effect: A systematic review and meta-analysis of randomized controlled trials
Authors: Fauzan Muhammad Ilham , Daryanto Besut , Budaya Taufiq Nur , Makkaraka Moh. Anfasa Giffari , Fakhri Muhammad , Rahman Ilham Akbar 
Published: November 2024

Introduction and Objectives: Premature ejaculation (PE) occurs in 31% of productive men aged 18-59 years, leading to disappointment and avoidance of sexual relations. The current guideline of treatment for PE is Dapoxetine, which possesses several adverse effects causing the limitation of long-term use. Silodosin, an alpha-1 blocker, has been proposed as a new option for treating PE due to its minimal side effects. Therefore, our study aims to assess the efficacy of silodosin in treating PE.Materials and Methods: This systematic review and meta-analysis was in accordance with Cochrane Handbook guidelines. Comprehensive literature search was conducted in several databases including PubMed, ScienceDirect, and Cochrane Central Register of Controlled Trials. The studies were included if they met the following criteria: (1) Involving premature ejaculation patients; (2) Intervention using silodosin; (3) Comparing placebo or other therapies for PE (4) Outcome includes the Intravaginal Ejaculation Latency Time (IELT) and reported adverse events related to the therapy. Study quality was assessed using Cochrane risk-of-bias criteria. Statistical analysis in this study was performed using Review Manager 5.4 Results: A total of four studies were included in this meta-analysis. Our study showed that patients who received silodosin had a significantly longer IELT compared to control (MD: 132.54, 95% CI 51.51-213.57, p<0.001). However, patient treated with silodosin also possessed significantly higher risk of adverse event for developing reduced semen ejaculation (OR 10.79, 95% CI 3.46 – 33.67, p<0.0001).Conclusion: Silodosin significantly increased IELT. However, it also reduced semen ejaculation as its drug adverse effect. This result supports the clinical use of silodosin as an alternative treatment for premature ejaculation.
The learning curve for robotic-assisted pyeloplasty in urologists with no prior robotic experience using an <i>ex-vivo</i> model: A prospective, controlled study
Authors: Ayed Abdullah , Kallidonis Panagiotis , Tatanis Vasileios , Peteinaris Angelis , Liatsikos Evangelos , Natchagande Gilles 
Published: November 2024

Introduction: Despite the increasing trend of utilizing robotic techniques in pyeloplasty, little is known about the learning curve for robot-assisted pyeloplasty (RAP) amongst urologists with no prior robotic experience. Therefore, the present study aimed to evaluate the learning curve of residents in the last year or new urologists performing RAP using an ex-vivo model.Methods: A prospective ex-vivo model study was conducted including participants who were either residents in the last year or new urologists. All participants had obtained the E-BLUS certification or they were able to complete its 4 tasks successfully in a dry lab, without prior robotic experience. Each participant performed four consecutive RAPs using the Avatera system on an ex-vivo porcine model. The primary endpoint of the present study was the change in the average time to complete the anastomosis from the first to fourth attempts.Results: Nine urologists and 8 residents were enrolled in this study. All participants successfully completed the four RAP attempts. Each surgeon demonstrated a reduction in the time to complete anastomosis from the 1st to 4th attempt with an average of value of 4.41±1.06 minutes (p=0.003). The decrease in time was statistically significant in both urologists and residents subgroups (4.5±1.41 minutes p=0.049 and 4.33±0.71 minutes p=0.035, respectively). Conclusions: The training on the ex-vivo model could lead, in only a few attempts, to a significant improvement in skills and in the required time of experienced-naïve surgeons to complete a RAP.
Status of Food Safety in Correctional Homes: A Mixed-methods Study from West Bengal, India
Authors: Mitra Satabdi , Bhanja Sushanta , Basu Rivu , Majumdar Kunal Kanti , Joardar Gautam Kumar 
Published: November 2024

Abstract

Introduction:
Food safety and hygiene management are an important global public health concern. In correctional homes, people live with sketchy basic amenities and health-care facilities. Here the eating establishments run through mass self-catering services by inmates themselves. As noncompliance to hygienic and sanitary food handling can pose threat to food-borne illnesses, the current study was conducted to assess the status and bottleneck of safe food practice in eating establishments of correctional homes.

Materials and Methods:
A mixed-methods cross-sectional study was conducted over 10 months in three correctional homes of Kolkata. With pro forma based on Food Safety and Standard Rules, food and environmental hygiene of eating establishments was observed and thirty food handlers were assessed for knowledge and practice related to food hygiene. Two food samples from each establishment were collected for laboratory examination for contamination, if any. Superintendents and welfare officers were interviewed in-depth for barriers toward safe food practice. QDA miner lite, 2022 was used for the analysis.

Results:
All the three eating establishments were categorized as “poor” having total scores of <50% in various facets of food safety and none of the food handlers scored above cut-off value. One food sample has showed bacterial growth after incubation. Content analysis revealed knowledge gap in part of handlers besides unstructured monitoring, lack of health check-ups to have maximum coding frequency, and strongest links.

Conclusion:
Food safety in correctional homes under the study at each step including monitoring is dreary. Training of food handlers and their supervisors besides regular health screening is the need of the hour.
A comparative evaluation of the effect of matrix metalloproteinase inhibitor on the fracture resistance of endodontically treated teeth restored with Everstick-reinforced composite resin: An in vitro study
Authors: Dhok Vaishnavi Deepak , Khanvilkar Unmesh Deepak , Moogi Prashant Prakash , Bandekar Siddhesh Dattatray , Kshirsagar Shirin , Jadhav Sanket Rajendra 
Published: November 2024

Aim:
To evaluate the effect of applying a matrix metalloproteinase (MMP) inhibitor on the fracture resistance of root-filled teeth restored with Everstick fiber-reinforced composite resin.

Subjects and Methods:
After the selection of 60 freshly extracted human mandibular first molar, root canal access and standard uniformly sized mesio-occluso-distal (MOD) cavities were made and the teeth were randomly assigned into three groups (n = 20 each): Group I, the MOD cavity was first lined with flowable composite resin and then restored with composite resin. In Group II, Everstick fiber was placed into the bed of flowable composite in buccal–pulpal–lingual direction before the composite restoration was placed. In Group III, after etching of the cavity, a 2% chlorhexidine MMP inhibitor was applied. Then, the MOD cavity was restored same as group II. A universal testing machine was employed to compressively load the teeth at a cross-head speed of 0.5 mm/min till fracture. The maximum fracture loads were recorded in Newtons (N) and data were analyzed with one-way ANOVA and post-hoc Tukey tests.

Results:
Group III exhibited significantly higher fracture resistance compared to all other groups (P < 0.001), whereas Group I demonstrated the lowest fracture resistance.

Conclusion:
The utilization of Everstick glass fiber, combined with MMP inhibitor treatment, yielded the greatest fracture resistance. Hence, this method may be prioritized over conventional restoration techniques for strengthening root canal-treated teeth with structurally compromised crowns.
Impact of gamma radiation on marginal adaptation of nanohybrid composite and composition of dental hard tissues – Scanning electron microscopy and X-ray diffraction analysis: An in vitro pilot study
Authors: Bansal Dolphi , Bansal Rajinder Kumar , Dora Tapas Kumar , Bansal Manu , Garg Reeshu , Kaur Manmeet 
Published: November 2024

Aims:
This pilot study aimed to compare the marginal adaptation of composite resin at the tooth-restoration interface, before and after radiation.

Subjects and Methods:
Fifteen extracted premolars were divided into 2 experimental groups (based on the timing of irradiation) and 1 control group of 5 teeth each. In Group I (control group), teeth were restored but not exposed to radiation at any stage, Group II: teeth were irradiated before cavity preparation and restoration, and Group III: after cavity preparation and restoration employing selective etch technique, teeth were exposed to radiation. The samples were then sectioned buccolingually to analyze the extent of the marginal gap under scanning electron microscopy and compositional alteration of dental hard tissues by X-ray diffraction study. The data collected were analyzed statistically.

Statistical Analysis Used:
The statistical software used was IBM SPSS version 23 New York, USA, and analysis was done using two-way ANOVA followed by Turkey’s post hoc test, this difference in the mean marginal gap between all three groups was nonsignificant (P ≥ 0.05).

Results:
In the control group (Group I), a minimum gap (4.203 µm ± 0.533) was observed at the tooth-restoration interface, indicating the highest level of adaptation as compared to Group II (5.816 µm ± 0.762) and Group III (4.862 µm ± 1.018). This suggests that radiation adversely affected the bonding between composite materials and both enamel and dentin, attributed to the alterations induced by radiotherapy in the chemical, physical, and morphological properties of both tooth structure and composite resin.

Conclusions:
Ionizing radiations adversely affect the bonding between enamel, dentin, and composite resin. Hence, restorative procedures should be performed before undergoing radiotherapy.
Shear bond strength evaluation of bioactive restorative materials on pretreated carious dentin-influence on silver diamine fluoride, potassium iodide, and glutathione
Authors: Sharma Nupur , Nikhil Vineeta , Mishra Preeti , Ravinder Rohit 
Published: November 2024

Background:
Silver diamine fluoride (SDF) has gained popularity for its caries-arresting properties, yet its tendency to cause esthetic concerns due to black-staining limits its widespread acceptance.

Aim:
The aim of the study was to evaluate and compare the shear bond strength of Activa BioActive and Giomer restorative material with different protocols of SDF pretreatment on carious dentin.

Materials and Methods:
Ninety-two extracted teeth were decoronated at the cementoenamel junction, sectioned 1 mm into dentin, mounted in acrylic resin and randomly divided into four (n = 8) control and six (n = 10) experimental groups. Seventy-six samples underwent demineralization process for a period of 14 days for artificial carious dentin (ACD) formation. The samples categorized based on the dentin substrate (sound or ACD) were subjected to various SDF pretreatment protocols, i.e., only SDF, SDF with potassium iodide (KI), and SDF with glutathione (GSH). Further, bioactive restorative materials, i.e., Activa BioActive and Giomer (Beautifil II), were placed on it, and the samples were subjected to shear bond strength testing.

Statistical Analysis:
Independent t-test was run to analyze the values obtained.

Results:
Giomer exhibited better mean bond strength with SDF, SDF + KI, and SDF + GSH (6.56, 4.67, and 3.34 mega-pascals [MPa], respectively) compared to Activa BioActive (3.42, 3.27, and 2.96 MPa, respectively).

Conclusion:
This study contributes to understanding the interplay between SDF application protocols, esthetic concerns, and the adhesive properties of bioactive restorative materials. Giomer exhibited enhanced bond strength after SDF application, unlike Activa BioActive. In addition, incorporation of KI or GSH adversely affected the bond strength of both the restorative materials, underscoring the critical need for cautious clinical application.

Clinical Relevance:
This study highlights the importance of selecting appropriate dentin pretreatment agents to maximize the bond strength of bioactive restorative materials with carious dentin. SDF application significantly enhanced the bond strength of Giomer with carious dentin compared to Activa BioActive, thus, making it a good choice for restoring nonesthetic areas. In addition, the application of KI or GSH to mitigate discoloration of carious dentin negatively affected the bond strength of both, Activa BioActive and Giomer. Thus, the clinicians should weigh the benefits of SDF against potential bond strength reductions when using KI or GSH, especially for esthetic restorations.
Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon
Authors: Metwally Yasser Gaber , Elnady Khaled Yehia , El-Ghaffar Tarek Abd , Seddik Eman Hesham , Shaker Ahmed , Swailem Fathy Mohamed 
Published: November 2024

Abstract

Background:
The optimal therapeutic strategy for coronary intervention in edge in-stent restenosis (edge ISR) remains less well-defined.

Aim:
The aim of this study was to assess 12-month outcomes of re-stenting using drug-eluting stents (DESs) versus using drug-eluting balloon (DEB) for managing coronary edge ISR.

Patients and Methods:
One hundred and four patients with edge ISR were randomly assigned to either DES or DEB. The primary endpoint was stent failure at 12-month follow-up.

Results:
Significantly lower target vessel revascularization among the DEB group compared to restenting group, (7.7% vs. 23.1%, P = 0.04). Likewise, target vessel-related myocardial infarction rate was significantly lower among the DEB group than restenting (5.7% vs. 23.1%, P = 0.04). On the other hand, there were no significant differences in the rates of deaths or restenosis between the two groups.

Conclusion:
The DEB is superior to the DES with better both safety and efficacy.
Percutaneous Closure of Postmyocardial Infarction Ventricular Septal Rupture – A Single Center Experience from the Eastern Part of India
Authors: Islam Nurul , Saha Siddhartha , Parida Ashok Kumar , Dutta Satyendra Nath 
Published: November 2024

Abstract

Background:
Postinfarction ventricular septal rupture (VSR) is a rare but lethal mechanical complication of an acute myocardial infarction (AMI). It results in 90%–95% mortality within 2 months of diagnosis without any kind of intervention. Given high surgical mortality, transcatheter closure has emerged as a potential strategy and as an alternative to high-risk surgical closure. Indian data on percutaneous device closure of post-AMI VSR are limited; hence, we report our resource-limited single-center experience with different kinds of occluder devices for closure of post-AMI VSR.

Methods and Results:
In this single-center, retrospective cohort study, patients who underwent transcatheter closure of postmyocardial infarction (MI) VSR between 2018 and 2024 at Health World Hospitals in Durgapur, West Bengal, were included. The primary outcome was a mortality rate of 30 days. The study population was eleven primary cases of post-MI VSR. The mean age of the population was 61 years. The majority of the patients had anterior wall MI (54.5%), and the remaining had inferior wall MI. Different kinds of devices (Amplatzer atrial septal occlude, post-MI VSD device, and Konar-Multifunctional Occluder) were used to close VSR. Successful closure was performed in 9 patients (81%) with minimal residual shunt in 2 patients. Of 9 cases, 3 patients expired; one was lost to follow-up, and the rest are doing well at 30-day follow-up.

Conclusion:
Transcatheter closure of PMI VSRs can be performed with different kinds of devices with high technical success, relatively low procedural complication rates, and a good 30-day survival even in a setup outside the metropolis with limited availability of devices, as an alternative to very high-risk surgical closure.