bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconstruction of the spinal cord of spinal transected dogs with polyethylene glycol
Authors: Ren Shuai , Liu Zehan , Kim C. Yoon , Fu Kuang , Wu Qiong , Hou Liting , Sun Linlin , Zhang Jian , Miao Qing , Kim Jin , Bonicalzi Vincenzo , Guan Xiangchen , Zhang Mingzhe , Zhang Weihua , Xu Junfeng , Canavero Sergio , Ren Xiaoping 
Published: April 2019

Background:
Our study shows that a membrane sealant/fiber fusogen polyethylene glycol (PEG) applied immediately on a sharp section of the spinal cord can mend the cord and lead to exceptional levels of motor recovery, with some animals almost normal.

Materials and Methods:
Before deploying such technology in man, long-term data in large mammals that exclude delayed complications (e.g., central pain), confirm the stability of motor recovery, and provide histological evidence of fiber regrowth are necessary. Here, we provide such evidence in dogs followed up over 6 months and in 2 cases up to 1 year along with imaging and histologic data.

Results:
We show that dogs whose dorsal cord has been fully transected recover locomotion after immediate treatment with a fusogen (PEG). No pain syndrome ensued over the long term. Diffusion tensor imaging magnetic resonance and histological, including immunohistochemical, data confirmed the re-establishment of anatomical continuity along with interfacial axonal sprouting.

Conclusions:
This study proves that a form of irreversible spinal cord injury (SCI) can effectively be treated and points out a way to treat SCI patients.
Management of oculomotor nerve schwannoma: Systematic review of literature and illustrative case
Authors: Muhammad Sajjad , Niemelä Mika 
Published: April 2019

Background:
Oculomotor nerve schwannoma (ONS) is an extremely rare intracranial benign tumor. Till date, there is no standard treatment of oculomotor schwannoma. Here, we present an illustrative case report of ONS, perform a systematic review of literature on surgically and radiosurgically treated cases and morbidity related to both treatment modalities.

Methods:
We performed a systematic review of literature for cases with ONS treated with surgery or radiosurgery using PubMed/Ovid Medline.

Results:
Till date, there are 60 reported cases of ONS (45 treated surgically and seven radiosurgically) with the dominance of female gender (53%) and mean age of 35.2 years (Range 1–66). In 8% of the cases, there was no involvement of cranial nerve (CN) III and 92% of the cases CN III alone or together with CN II, IV, V, and VI. In 67% of the cases a complete resection and 33% a partial resection performed. In 73% of the cases, postoperative third nerve palsy was documented, 22% improved after surgery and in around 5% of cases, the outcome was not described. In the radiosurgically treated cases of nonvestibular schwannoma including ONS, the progression-free interval of approximately 2 years was above 90%.

Conclusion:
Due to the high rate of postoperative complete oculomotor nerve palsy, a subtotal resection avoiding the nerve injury seems to be a feasible option. Radiosurgery is another option to treat small size schwannoma. A combined treatment with microsurgery followed by radiosurgery may allow effective treatment for large size oculomotor schwannoma.
Extradural en-plaque spinal lipomatous meningioma: A case report and literature review
Authors: de Eulate-Beramendi Sayoa Alvarez , Piña-Batista Kelvin Manuel , Rial-Basalo Juan Carlos 
Published: April 2019

Background:
Extradural spinal meningiomas are rare, and few appear as lipomatous meningiomas in an “en-plaque” form. The transitional fibroblastic subtype, with lipid accumulation within the tumoral cells, is typically more aggressive and surgically challenging to resect.

Case Description:
A 42-year-old male presented with neck pain and progressive paresthesias in both upper extremities. Based on the radiological findings, the tentative preoperative diagnosis was lymphoma. However, the biopsy confirmed a meningioma. The patient underwent a combined extradural anterior and posterior approach, resulting in full tumor resection. Histopathologically, the final report documented a lipomatous meningioma.

Conclusion:
Extradural spinal lipomatous meningiomas (i.e., “en-plaque”) are rare and typically result in rapid clinical deterioration. The radiological diagnosis may be difficult, while ultrasonography helps to define their extradural location facilitating planning for gross total anterior/posterior excision where indicated.
Endovascular treatment of idiopathic intracranial hypertension caused by multiple venous sinus stenoses
Authors: Morisaki Yudai , Nakagawa Ichiro , Omoto Koji , Wada Takeshi , Kichikawa Kimihiko , Nakase Hiroyuki 
Published: April 2019

Background:
Idiopathic intracranial hypertension (IIH) shows symptoms by elevating intracranial pressure. Although sinus stenosis has been detected in many patients with IIH, the role of sinus stenosis in IIH remains obscure. Endovascular treatment for IIH due to transverse sinus stenosis has been frequently documented; however, IIH due to multiple sinus stenoses including the superior sagittal sinus (SSS) is rare. Here, we report a case of IIH due to multiple sinus stenoses treated by sinus stenting.

Case Presentation:
A 47-year-old woman suffered from intractable headache with IIH presented with stenosis of the right transverse and SSS. Stent placement was carried out since intracranial hypertension and trans-stenotic cerebral venous pressure gradient (CVPG) were presented, and her intractable headache disappeared.

Conclusion:
IIH can be caused by venous sinus stenoses and stent placement could be an appropriate treatment in patients who demonstrated a CVPG.
The State of Students’ Mental Health: A Case Study
Authors: Abdul Rashid Mas Anom , Azman Othman Mohd Noor , Ibrahim Abdul Razak 
Published: April 2019

The Malaysian Ministry of Health has aired its concern towards the state of Malaysian students’ mental health in the late 2016. Statistics revealed a worsening state of mental health problems among Malaysian students, which shows that there is an increase cases of mental health from 2011 to 2016. Experts cite anxiety and depression as the main causes of mental health problems among students although not ruling out the influence of drugs as a factor. Hence, this study is aimed to seek some answers to the state of the students overall mental health, what are the most influential factor that affects their mental health and how they manage these issues. A total of 350 students participated in this study and findings revealed that 50% of the students suffered some kind of depressions triggered by various factors.
PENGEMBANGAN INSTRUMEN SIKAP SISWA SEKOLAH MENENGAH PERTAMA TERHADAP MATA PELAJARAN IPA
Authors: Astalini Astalini , Kurniawan Dwi Agus 
Published: April 2019

Tujuan penelitian ini adalah untuk pengembangan instrumen penilaian sikap siswa terhadap mata pelajaran IPA. Instrumen yang dikembangkan berupa angket yang terbagi menjadi pernyataan positif dan pernyataan negatif. Metode penelitian yang digunakan adalah Research and Development (R&D) atau umumnya dikenal dengan penelitian pengembangan. Subjek penelitian adalah siswa SMPN Se-Kabupaten Muaro Jambi dengan menggunakan teknik purpossive sampling, maka sampel penelitian sebanyak 550 siswa. Hasil penelitian menunjukkan instrumen angket yang valid sebanyak 56 butir dari total 70 butir pernyataan, dengan nilai reliabilitas (cronbach alpha) sebesar 0,842.
Enhancement of blocking-time theory to represent future interlocking architectures
Authors: Büker Thorsten , Graffagnino Thomas , Hennig Eike , Kuckelberg Alexander 
Published: April 2019

Recently, railway-infrastructure managers and suppliers have launched major programs with the aim to revise – or even reinvent – the overall interlocking architectures plus adjacent systems and operational principles. Representatives of such initiatives are “SmartRail 4.0” and “Digitale Schiene Deutschland”. Those programs are backed-up by a set of motivations, namely: Existing command and control technology is overaged or becomes outdated, skills to maintain technology get lost due to demographic aging, applied technology is expensive and does not allow any further capacity gain.Since capacity improvement is a core target of all programs, there is a severe need to express the capacity impact of the related system architecture. Such quantifications serve the broad portfolio from political decision processes to detailed requirement specifications.This article describes necessary extensions of the blocking-time model to meet the requirements of future interlocking architectures in detail. It contributes to extent the standardised blocking-time model in such a manner, that its applicability is ensured in different setups. Besides providing and extending the theoretic background, the article provides examples of practical computations and applications. They cover sensitivity analysis to elaborate the decisive impact parameters on headway times as well as timetabling-studies based on a future technology setup.
Standard APIs and link prediction for the digital thread
Authors: Reichwein Axel , Jenaro-Radaban Guillermo , Lattmann Zsolt 
Published: April 2019

Addressing cross-cutting concerns such as traceability, change management, and trade-off studies is complex in multi-disciplinary engineering. These aspects can only be addressed efficiently if organizations take a global level perspective on data and view data from many different sources as a whole.Traditionally, enterprise software applications are coupled to a specific data store. The application layer communicates with the data layer through an interface to perform basic create-read-update-delete (CRUD) operations. These operations are common to most applications. By standardizing the interface between application and data layers through a standard API, enterprise software applications can be decoupled from specific data stores. APIs in general have 2 aspects: the API protocol and the semantics of the data being consumed and produced by the API. The latter aspect is independent of technology and is based on reaching a consensus between domain experts, which can be much harder than standardizing the API protocol using common technology.Standardizing the API protocol can help organizations access data from various sources, reuse old data with new applications, and connect data to establish a digital thread. Several technologies such as REST, Linked Data, Hypermedia APIs, GraphQL, or collections of standards such as OSLC and Solid can be used to standardize the API protocol. The main ideas of these technologies as well as their adoption levels are presented. The impact of a standard API protocol for organizations, application vendors, and standardization organizations is explained. The opportunities as well as remaining challenges related to a standard API ecosystem are described.
SEJARAH ASUS
Authors: Adlaimi Nazri 
Published: April 2019

ASUS, adalah sebuah perusahaan berbasis di Taiwan yang memproduksi komponen komputer seperti papan induk, kartu grafis, dan notebook. Asus belakangan ini mulai memproduksi PDA, Telepon genggam, monitor LCD, tablet dan produk komputer lainnya. Pesaing utamanya termasuk MSI, dan Gigabyte.Asus pada 2005 menjual papan induk lebih banyak dari perusahaan lainnya, termasuk 30 juta pada 2004. Angka ini termasuk kontrak merek lain. Asus juga memproduksi komponen untuk perusahaan lain, termasuk PS2 Sony dan AppleIpod, iBook, dllASUS banyak dipilih pengguna karena berani memberikan garansi 2 tahun untuk produk notuytv yang dibuatnya.Pada tahun 2014 Asus menggandeng PT Dragon Computer &amp; communication untuk menjadi distributor utama notebook dan tablet di Indonesia dan berhasil menjadi merek nomor satu hingga saat ini (menurut data IDC dan GFK).Asus yang merupakan perusahaan "Public" telah mendaftar pada lantai Bursa Efek Taiwan dengan kode 2357 dan daftar sekunder di London Stock Exchange dengan kode ASKD.
Signal Intensity of High B-value Diffusion-weighted Imaging for the Detection of Prostate Cancer
Authors: Rezaeian A , Tahmasebi Birgani M J , Chegeni N , Sarkarian M , Hanafi M Gh , Akbarizadeh Gh 
Published: April 2019

Background: Diffusion-weighted imaging (DWI) is a main component of multiparametric MRI for prostate cancer detection. Recently, high b value DWI has gained more attention because of its capability for tumor characterization.Objectives: To assess based on histopathological findings of transrectal ultrasound (TRUS)-guided prostate biopsy as a reference, an increase in signal intensity of prostatic lesions in comparison with normal background tissue on high b-value diffusion-weighted images could be a sign of malignancy. Material and Methods: Fifty-three consecutive patients retrospectively included in the study. All patients underwent routine TRUS-guided prostate biopsies involving 12 cores after the magnetic resonance imaging (MRI) examinations. In seventeen patients (n =35 lesions), the prostate cancer was histologically confirmed by TRUS-guided prostate biopsy. The biopsy results of other patients were negative. Signal intensities on the high b-value (1600 s/mm2) images of the peripheral zone, the central gland, and the defined lesions were evaluated using region of interest-based measurements. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for prostate cancer detection using signal intensity of high b value diffusion-weighted images were calculated.Results: In the patients with confirmed prostate cancer, fourteen had visually increased SI on the high b-value images. The SI of lesions for these patients was higher than the SI of peripheral zone (22±18%) or central gland (31±20%). In patients with a negative biopsy, eight had visually increased SI on the high b-value images. The SI of lesions for these patients was 23±21% and 35±18% higher than the SI in the peripheral zone and the central gland, respectively. The sensitivity, specificity, PPV, and NPV for prostate cancer using SI of high b value DWI were 71, 87, 62, and 87 %, respectively.Conclusions: Visually increased SI on the high b-value images can be an indication of malignancy, although some benign lesions also show this increase in signal intensity.
MENINGKATKAN KEMAMPUAN SISWA DALAM PEMECAHAN MASALAH MATEMATIK MELALUI PENDEKATAN METAKOGNITIF
Authors: Nanang Nanang 
Published: April 2019

Penelitian eksperimen ini bertujuan untuk mengetahui peningkatan dan membandingkan kemampuan pemecahan masalah matematik pada kelompok siswa yang pembelajarannya menerapkan pendekatan metakognitif (PM) dan pendekatan konvensional (PK). Instrumen yang digunakan berupa tes kemampuan pemecahan masalah matematik. Analisis data dilakukan dengan uji gain ternormalisasi dan uji perbedaan dua rata-rata. Hasil utama dari penelitian ini adalah secara keseluruhan siswa yang pembelajarannya dengan PM (kelompok eksperimen) peningkatan kemampuan pemecahan masalah matematiknya termasuk tinggi dan secara signifikan lebih baik dibandingkan dengan siswa yang pembelajarannya dengan PK (kelompok kontrol).
PEMBELAJARAN BERBASIS MASALAH UNTUK MENINGKATKAN KEMAMPUAN KOMUNIKASI MATEMATIK SISWA SEKOLAH MENENGAH PERTAMA
Authors: Sofyan Deddy 
Published: April 2019

Tujuan penelitian ini adalah untuk menelaah model pembelajaran yang lebih baik dalam meningkatkan kemampuan komunikasi matematik pada kelompok siswa yang mengikuti pembelajaran berbasis masalah terbuka, pembelajaran berbasis masalah terstruktur, dan pembelajaran konvensional. Penelitian ini merupakan studi eksperimen berbentuk kelompok kontrol pretes-postes. Populasi Penelitian ini adalah Siswa SMP Negeri di kabupaten Garut yang termasuk kategori sekolah kelompok tinggi. Sampel penelitian ini adalah siswa kelas VIII salah satu SMP Negeri di kabupaten Garut. Hasil yang diperoleh adalah kemampuan komunikasi matematik siswa yang mengikuti pembelajaran berbasis masalah terbuka sama baiknya dengan siswa yang mengikuti pembelajaran konvensional. Kemampuan komunikasi matematik siswa yang mengikuti pembelajaran berbasis masalah terbuka dan pembelajaran konvensional lebih baik daripada siswa yang mengikuti pembelajaran berbasis masalah terstruktur.
PENGEMBANGAN BAHAN AJAR METODE NUMERIK DENGAN PENDEKATAN METAKOGNITIF BERBANTUAN MATLAB
Authors: Nasution Mara Doli , Nasution Elfrianto , Haryati Feri 
Published: April 2019

Penelitian ini bertujuan untuk mengembangkan materi pembelajaran untuk metode numerik which dirancang dengan pendekatan metakognitif pemrograman dibantu matlab. Model pengembangan bahan pembelajaran menggunakan Penelitian dan Pengembangan (R & D) WHO metode dikembangkan oleh Borg dan Gall dan dikombinasikan dengan model pengembangan pengajaran Dick dan Carey. Populasi untuk uji coba produk adalah mahasiswa UMSU jurusan pendidikan matematika. Instrumen which digunakan adalah kuesioner. Produk ini memiliki tiga langkah uji gruops Termasuk pribadi, gruops kecil dan lapangan. Sebelum uji coba produk, peneliti tidak ahli sidang validasi atas isi dan desain bahan pembelajaran untuk metode numerik dengan menggunakan kuesioner Menurut indikator yang telah ditentukan. Kemudian kuesioner dianalisis untuk melihat persentase dan kriteria validasi bahan Learning. Hasil dari penelitian ini adalah metode numerik yang dirancang diktat digunakan metakognitif pendekatan dibantu pemrograman Matlab. This research aims to develop learning materials for numerical methods which be designed by Metacognitive approach assisted matlab programming . The development model of learning materials using Research and Development (R & D) methods who be developed by Borg and Gall and be combined with teaching development model Dick and Carey. The population for the product trials are UMSU students majoring in mathematics education. The instrument which be used is questionnaire . This products trials have three steps including personal gruops, small gruops and the field. Before products trials , the researcher does the expert validation trial for the content and design of learning materials for numerical methods using questionnaires according to the indicators that have been determined. Then the questionnaire be analysed to see the percentage and the validation criteria of Learning materials. The results of this research is a numerical method diktat be designed used metacognitive approach assisted matlab programming.
MENINGKATKAN KEMAMPUAN PEMECAHAN MASALAH DAN KOMUNIKASI MATEMATIK MELALUI PENDEKATAN PROBLEM POSING DALAM PEMBELAJARAN MATEMATIKA DI SMA
Authors: Sofyan Deddy , Madio Sukanto Sukandar 
Published: April 2019

Tujuan penelitian ini adalah untuk meningkatkan kemampuan siswa SMA dalam pemecahan masalah dan komunikasi matematik melalui pendekatan problem posing dalam pembelajaran matematika. Metode penelitian yang digunakan adalah metode kuasi eksperimen. Populasi penelitian ini adalah siswa di salah satu SMA Negeri di Kabupaten Garut. Sampel penelitian dipilih secara acak berdasarkan kelas, sampelnya adalah kelas XII IPA 1 yang mendapat pembelajaran menggunakan pendekatan problem posing dan siswa kelas XII IPA 3 yang mendapat pembelajaran konvensional. Simpulan hasil penelitian ini adalah bahwa dalam pembelajaran matematika di SMA: 1. Kemampuan pemecahan masalah matematik siswa yang mendapatkan pendekatan problem posing lebih baik dibandingkan dengan konvensional, 2. Tidak terdapat perbedaan kemampuan komunikasi matematik antara siswa yang mendapatkan pendekatan problem posing dengan konvensional, 3. Tidak terdapat kaitan yang signifikan antara kemampuan pemecahan masalah matematik dengan kemampuan komunikasi matematik pada siswa yang mendapatkan pendekatan problem posing. The purpose of this research is to improve the ability of high school students in problem solving and communication of mathematics through problem posing approach to learning mathematics. The method used is a quasi-experimental method. The study population was one of the students in high schools in Garut. Samples were selected randomly based on the class, the sample is a class XII IPA 1 gets learning using problem posing approach and class XII IPA 3 students who received conventional learning. Conclusion The results of this study is that the study of mathematics in high school: 1. mathematical problem solving ability of students to get a better problem posing approach compared to conventional, 2. there is no difference in the ability of mathematical communication between students who received conventional approach to problem posing, 3. there was no significant association between mathematical problem solving skills with communication skills in students who get a mathematical problem posing approach.
KEMAMPUAN PENALARAN ANALOGIS SANTRI DALAM GEOMETRI: PENELITIAN KUALITATIF DI SEBUAH PONDOK PESANTREN
Authors: Ramdhani Sendi 
Published: April 2019

AbstrakPenelitian ini bertujuan untuk menyelidiki kemampuan penalaran analogis santri dalam geometri dan mengidentifikasi kesulitan dan hambatan mereka. Penulis mendeskripsikan bagaimana kemampuan analogis dalam pemahaman konsep geometri, kemampuan penalaran analogis dalam teorema dan sifat, dan kemampunan penalaran analogis dalam masalah geometri. Penelitian ini merupakan bagian dari pengembangan bahan ajar geometri untuk meningkatkan kemampuan penalaran analogis santri. Adapun metode penelitiannya menggunakan penelitian kualitatif dalam materi teorema Pythagoras, aturan kosinus, dan teorema garis tinggi segitiga yang melibatkan 80 santri di sebuah Pondok Pesantren di Bandung, Indonesia. Hasil dari penelitian ini menemukan bahwa kemampuan penalaran analogis santri berada di kategori rendah dan cukup. Berdasarkan hasil tes dan wawancara menunjukkan santri kesulitan menuliskan persamaan Pythagoras berdasarkan gambar segitiga siku-siku dalam berbagai konteks, menuliskan persamaan kosinus berdasarkan definisi verbal dan gambar, melukis segitiga siku-siku berdasarkan persamaan Pythagoras, melakukan penalaran analogis antara teorema Pythagoras dan aturan kosinus, dan melakukan penalaran analogis berdasarkan teorema. Rekomendasi dari penelitian ini berupa kesulitan-kesulitan dan kelemahan-kelemahan santri dalam kemampuan penalaran analogis yang akan menjadi landasan untuk mengembangan bahan ajar geometri. AbstractThis study aims to investigate the analogical reasoning ability of santri in geometry and identify their difficulties and constraints. The author describes how analogical reasoning in understanding the concepts of geometry, analogical reasoning in theorems and properties, and the use of analogical reasoning in geometry problems. This research is part of the development of geometry teaching materials to improve the analogical reasoning ability of santri. The research method uses qualitative research in the material of Pythagoras theorem, the law of cosine, and triangle altitude theorem that involves 80 santri at a Pondok Pesantren in Bandung, Indonesia. The results of this study found that the santri's analogical reasoning abilities were in the low and sufficient category. Based on the results of the tests and interviews it is difficult for students to write Pythagoras equations based on right triangle images in various contexts, writing cosine equations based on verbal definitions and drawings, painting right triangles based on Pythagoras equations, analogical reasoning between Pythagorean theorem and cosine rules; doing analogical reasoning based on the theorem. The recommendation of this research is the difficulties and weaknesses of santri in analogical reasoning ability that will be the basis for developing geometry teaching materials.