bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ankle Reconstruction in Charcot's Neuroarthropathy: Challenges and Solutions
Authors: Panchbhavi Vinod K 
Published: September 2019

ABSTRACT
Ankle injuries in the presence of neuropathy have potential to cause deformity in the ankle, which can in turn cause ulcerations and infections leading to significant morbidity including loss of limb or even life. These injuries although devastating can start off innocuously and may not be immediately apparent to the patient because of lack of pain. This can lead to a late presentation. Often, the main concern is swelling, for which the patient seeks attention. And even when medical attention is sought, unless the physician is vigilant, the condition can potentially be missed or misdiagnosed as deep vein thrombosis or cellulitis. A sprain or even a fracture in the ankle is not suspected as the patient retains the ability to walk. This condition and its true nature further escapes detection if, as often is the case, a nonweight-bearing radiograph is obtained. Radiographs obtained without the weight-bearing or other stress modality may not reveal the instability at the ankle joint due to ligament damage. A thorough clinical evaluation including assessment for neuropathy and weight-bearing radiographs are necessary for diagnosis. Stable fractures and ankle sprains can be managed conservatively in a cast or boot. Unstable ankle following ligamentous disruption and/or fractures in the vicinity of the ankle needs internal or external stabilization. The stabilization in the presence of neuropathy should be stronger and the protection from weight bearing last longer and twice that used for patients with similar condition but without neuropathy.

How to cite this article
Panchbhavi VK. Ankle Reconstruction in Charcot's Neuroarthropathy: Challenges and Solutions. J Foot Ankle Surg (Asia-Pacific) 2016;3(2):65-70.
Transposition of Tibialis Anterior to the Cuboid after Tarsometatarsal Amputation
Authors: Bal Arun , Moonot Pradeep , Qureshi Ammar 
Published: September 2019

ABSTRACT
Forefoot and midfoot amputees are prone to develop nonhealing ulcers at the closure site. This mainly occurs due to the limited dorsiflexion ability of the ankle and associated loss of protective function as seen in diabetics. One of the proposed methods to prevent these postamputation ulcers includes tendoachilles lengthening during the procedure. We describe three cases with nonhealing ulcers on the lateral aspect after a midfoot amputation. All of the cases underwent a tibialis anterior transposition to the lateral aspect of the foot to correct the deformity and at the same time also achieved healing of the ulcers.

How to cite this article
Moonot P, Bal A, Qureshi A. Transposition of Tibialis Anterior to the Cuboid after Tarsometatarsal Amputation. J Foot Ankle Surg (Asia-Pacific) 2016;3(2): 107-110.
Ultrasonography-guided Platelet-rich Plasma Injection in Chronic Plantar Fasciitis
Authors: Gaur Tribhuwan NS , Rao Harish , Rai Garjesh S 
Published: September 2019

ABSTRACT

Introduction
Heel pain is a very common problem. The most common cause of heel pain is plantar fasciitis, and this often refractory to conservative treatment leads to disability. Platelet-rich plasma (PRP) derived from autologous blood containing high concentration of growth factors helps in tissue healing, so it is postulated to promote native tissue regeneration. The purpose of this work was to study the effectiveness of PRP in the treatment of chronic plantar fasciitis.

Materials and methods
The study was conducted in Orthopedic Department in collaboration with Radiodiagnosis Department at People's College of Medical Sciences and Research Centre, Bhopal, Madhya Pradesh, India. In this study, there were 44 patients, with 48 feet affected by plantar fasciitis.

Results
All patients were evaluated preinjection and postinjection by visual analog score. There was significant improvement after injection and no adverse reaction was seen.

Conclusion
Platelet-rich plasma is considered as a safe therapeutic option. It also effectively decreases heel pain in chronic plantar fasciitis.

How to cite this article
Gaur TNS, Rao H, Rai GS. Ultrasonography-guided Platelet-rich Plasma Injection in Chronic Plantar Fasciitis. J Foot Ankle Surg (Asia-Pacific) 2017;4(1):1-4.
Surgical Management of Haglund's Syndrome in Nonathletes: A Retrospective Review
Authors: Agarwala Sanjay , Agrawal Pranshu , Sobti Anshul S 
Published: September 2019

ABSTRACT

Aim
The present study was carried to retrospectively analyze the outcomes of patients with Haglund's syndrome treated with author's preferred technique and to compare and validate its results by comparing with the available literature.

Materials and methods
Twenty-four patients who had undergone surgery for Haglund's syndrome between 2008 and 2014 were identified retrospectively from records and included in the study cohort. Visual analog scale (VAS) score and American Orthopedic Foot and Ankle Score (AOFAS) were computed preoperatively and at each follow-up, the records of which were available through patient notes. The mean follow-up period was 32 months (12—55 months).

Results
The VAS score improved from a mean of 6.9 to 0.5 at 6 weeks follow-up and to 0.12 at 12 weeks follow-up. The mean AOFAS increased from 55.54 ± 7.26 to 91.20 ± 6.84 at 12 weeks follow-up. None of the patients had any significant complications. At 1 year follow-up, all the patients had returned to their predisease activity level.

Conclusion
Open surgical management with an individualized approach provides good to excellent outcomes with minimal complication rates.

How to cite this article
Agarwala S, Agrawal P, Sobti AS. Surgical Management of Haglund's Syndrome in Nonathletes: A Retrospective Review. J Foot Ankle Surg (Asia-Pacific) 2017;4(1):19-22.
The Lauge-Hansen Classification for Ankle Fractures: Is it Relevant in 2017?
Authors: Sharma Siddhartha , Mehta Nikhil , Dhillon, Mandeep S , Kumar, Lokesh 
Published: September 2019

ABSTRACT
Despite being one of the commonest fractures, classifications of ankle injuries are still debated, with modern surgeons decrying the use of the so-called antiquated system based on injury mechanisms. Despite glaring lacunae, especially with lack of reproducibility using modern methods, and an understanding that many fractures which we now see routinely may not fit into this classification, the Lauge-Hansen classification is still worth preserving. It clarifies some, if not most deforming forces, allows us to understand the ankle injury in a three-dimensional concept, both on the medial and lateral sides, and allows an understanding of reduction methods. The limitations in its use are the lack of prognostication ability, the fact that most reductions are now done open, and the recognition of some transitional and posterior malleolar injuries unclassifiable by it. Not being alphanumeric is another disadvantage in the computer age. Nevertheless, it is an important landmark in the history of orthopedics, and in the development of our understanding of ankle fractures. Even in 2017, it is too important a piece of work to be discarded, and modern orthopedic students are encouraged to gain an understanding of this classification system, and to combine it with the newer ones to get an overall picture of the ankle injury.

How to cite this article
Dhillon MS, Kumar L, Sharma S, Mehta N. The Lauge-Hansen Classification for Ankle Fractures: Is it Relevant in 2017? J Foot Ankle Surg (Asia-Pacific) 2017;4(2):53-56.
Thalidomide in Axial Spondyloarthropathy: An Eastern Indian Experience
Authors: Paul Rudrajit , Sarkar Arijit , Bhattacharjee Urmimala , Baisya Ritasman , Biswas Pallab , Sarkar Rathindranath , Das Chandan K 
Published: September 2019

ABSTRACT

Background
Axial spondyloarthropathy (SpA) is seronegative arthritis which mainly affects young adults and causes much morbidity. Tumor necrosis factor-alpha (TNF-α) is one of the main mediators of inflammation in joints and enthuses in SpA. Nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologics like TNF-α inhibitors are the mainstay of therapy in SpA. However, in India, the cost is one limiting factor in the use of biologics for the treatment of SpA in eligible patients. Thalidomide is an oral TNF-α inhibitor which has reported benefit in axial SpA, and it is a cheap option in the Indian setting. However, there is almost no Indian data on its efficacy.

Materials and methods
This is a retrospective analysis of patients receiving thalidomide for axial SpA in the rheumatology clinic of a tertiary care hospital of Kolkata. In this clinic, thalidomide was used at 100 mg/day. Patients receiving thalidomide, who had completed at least one year follow up were included in the analysis. Assessment of SpondyloArthritis International Society (ASAS)-20, ASAS-40, and ankylosing spondylitis disease activity score with C-reactive protein (ASDAS-CRP) were measured three monthly during the follow-up. Side effect profile of thalidomide was also recorded.

Results
The completed data of 66 patients were analyzed. All patients were human leukocyte antigen (HLA) B27 positive. Ninety-five point percent fulfilled ASAS-20 criteria at 12 months and 71.2% fulfilled the ASAS-40 criteria at 12 months. Three patients were nonresponders. The average ASDAS-CRP score also decreased from 2.9 to 1.5 over one year.

Conclusion
In our study, oral thalidomide resulted in significant improvements in axial SpA. Further randomized controlled trials are needed to find the relative efficacy of thalidomide with respect to other forms of treatment.
Qualitative Research: Data Analysis
Authors: Paul Uttam , Arup Bandyopadhyay 
Published: September 2019

ABSTRACT
Qualitative research is a simple, inexpensive and effective tool in medical research. The data analysis in qualitative researches, though based on certain ground rules, do not follow a rigid process like the data analysis of quantitative researches. It is ongoing through and through method. One interesting feature of data collection and analysis in qualitative research is “constant comparison”. This is a highly unique method in this type of research as compared to the quantitative research. Qualitative researches usually involve inductive reasoning, but there is deductive reasoning also. The first step of analyzing qualitative data is to transcribe all data into English from vernacular language. This transcript is then subjected to selection of “codes” which are nothing but descriptive names applied to certain thoughts coming up repeatedly in a transcript. Several codes together make a broader “category”. Themes are emerged from categories which are broad categories of information. The process of transcript analysis is called “content analysis” and this is at the end converted into “thematic analysis” which gives the meaning of the whole research and the answers to the original research question(s). There is ‘consolidated criteria’ for reporting qualitative research (COREQ) which is a 32 item check list for interviews and focus group discussions.
Heart Transplant: A Brief History
Authors: Paul Rudrajit 
Published: September 2019

ABSTRACT
Cardiac transplant is a life-saving procedure and with the advancement in technology, it is rapidly becoming available for patients in all corners of the world. As the heart transplant program is extended to Eastern India, this is an opportune moment to look back on the history of this medical miracle and how we reached the current level of excellence. this article is a brief recount of that illustrious history.
Long non-coding RNA TP73-AS1 predicts poor prognosis and regulates cell proliferation and migration in cervical cancer
Authors: Song Zhijiao , Xing Feng , Jiang Huici , He Yuanying , Lv Jia 
Published: September 2019

IntroductionCervical cancer is one of the most common malignant tumors in women, which seriously affects women’s health, especially in developing countries. This study aims to investigate novel molecular markers for poor prognosis of cervical cancer to achieve correct guidance of clinical treatment, accurate assessment of prognosis, and provide a new basis for the choice of reasonable treatment options for cervical cancer patients.Material and methodsQRT-PCR was employed to investigate the expression of lncRNA TP73-AS1 in cervical cancer tissues and cell lines. COX multivariate analysis showed the relationship between TP73-AS1 expression and clinicopathological features of patients with cervical cancer. Colony formation and MTT assay detected the effect of TP73-AS1 on proliferation of cervical cancer cells. The effect of TP73-AS1 on migration and invasion of cervical cancer cells was determined by the wound-healing assay and transwell assay. Western blot was performed to assess the expression of EMT markers.ResultsThis study showed that lncRNA TP73-AS1 was up-regulated in cervical cancer tissues and cell lines (p < 0.001), and high expression of TP73-AS1 could be considered as an independent prognostic factor (p < 0.05). Moreover, lncRNA TP73-AS1 promotes cervical cancer cell migration and invasion, and knockdown of TP73-AS1 inhibits the growth of cervical cancer cells (p < 0.001).ConclusionsOur results indicated that lncRNA TP73-AS1 was up-regulated in cervical cancer tissues and cell lines, predicting poor prognosis of cervical cancer and regulating cell proliferation and migration.
Barreras legales de acceso a la vivienda social en la comuna de Santiago
Authors: Cáceres Michelle 
Published: September 2019

El acceso formal a la vivienda social en Chile se ha consolidado principalmente como una política de financiamiento a una solución habitacional. Si bien es considerada exitosa, deja de lado a un porcentaje importante de la población, la que se encuentra con una serie de barreras o nudos estructurales al momento de postular y termina por no calzar en el perfil requerido para ser sujeto de beneficios.
En este contexto, la comuna de Santiago, debido a su repoblamiento y crecimiento de las últimas décadas, es uno de los grandes focos de demanda habitacional y donde debido a sus características se dificulta acceder a vivienda social en la zona. El objetivo de este artículo es determinar por medio del análisis de los decretos DS.49 y DS.1 cuáles son las barreras legales con las que se encuentran los habitantes al postular y cómo se expresan en la comuna de Santiago.
La organización del espacio doméstico en la arquitectura vernácula de San Pedro de Atacama
Authors: Rojas Tabilo Víctor 
Published: September 2019

RESUMEN
Este trabajo se estructura sobre la discusión y el análisis de las relaciones sintácticas en la arquitectura vernácula y patrimonial del territorio atacameño, en relación a su unidad doméstica. En una primera aproximación, a través de la revisión de textos arqueológicos, relacionando algunos asentamientos prehispánicos del período formativo. Y en segunda instancia, a través del análisis de la vivienda típica atacameña, de alto valor patrimonial que se consolidaría a fines del siglo XIX e inicios de siglo XX en el oasis de San Pedro de Atacama. El enfoque de estas temporalidades, tan distantes, se realiza a través del reconocimiento de algunos aspectos jerárquicos que, como relaciones inmateriales, organizan el espacio construido a través de aquellas manifestaciones humanas, enraizadas en lo más profundo del entendimiento de cómo habitar estos territorios.
Ecosistema editorial y entorno público
Authors: Gonzalez Luna Vianney 
Published: September 2019

La producción editorial ha transformado históricamente los aspectos culturales y sociales de la humanidad, esto ha sucedido en diversas formas y a través de múltiples formatos, lo que nos lleva a preguntarnos sobre el estado actual de la industria y los procesos que han sido transformados por los avances tecnológicos, así mismo el cambio en los lectores.
Ante estas variaciones nos cuestionamos cómo es que la materialidad de los textos se vuelve efectiva y transformadora en escenarios como el entorno público y sus instituciones, tema del que se ha hablado poco en el sentido de conformar procesos cada vez más asertivos, y es aquí donde intervienen dos principales factores, el trabajo de un editor profesionalizado y el del diseñador como mediadores para visibilizar la voz del estado.
Four Models for Corporate Transformative, Open Innovation
Authors: Boni Arthur , Joseph Diana 
Published: September 2019

Four models are identified for organizations to pursue simultaneous core growth and transformative innovation leveraging open innovation principles: 1) corporate accelerators —engage with or create autonomous startups; 2) external startup platforms — engage with startups through established third parties, 3) consortia or alliances — leverage resources of peers and emergent players across the innovation ecosystem; and; 4) direct entrepreneurial approach -- work from within the organization to develop new units. We identify “innovation maturity” as the key factor to select which model is most appropriate for the organization. Additional considerations include the resources, processes and values of the organization, and the developmental status of the transformative technology. Model choice(s) are dynamic and can evolve over time as the innovation capacity of the organization matures and adapts to change.
Estudio histopatológico de tejido cardiaco de roedores infectados con Trypanosoma cruzi capturados en barrios suburbanos de Mérida, México
Authors: Ucan-Euan Fernando , Hernández-Betancourt Silvia , Arjona-Torres Madeleine , Panti-May Alonso , Torres-Castro Marco 
Published: September 2019

Introducción. Trypanosoma cruzi es el agente causal de la tripanosomiasis americana, enfermedad endémica en México. Los roedores Mus musculus y Rattus rattus son reservorios del parásito, el cual invade las fibras cardiacas y desarrolla nidos parasitarios produciendo diversas lesiones. Los estudios histopatológicos en roedores naturalmente infectados son escasos.Objetivo. Describir los tipos y las frecuencias de las lesiones microscópicas en muestras de tejido cardiaco de M. musculus y R. rattus infectados con T. cruzi capturados en Mérida, México.Materiales y métodos. Los roedores se capturaron en los barrios suburbanos de Mérida. Se extrajo el tejido cardiaco y se procesó por la técnica de inclusión en parafina y tinción con hematoxilina y eosina. Su examen se hizo con un microscópico convencional y se determinaron todas las lesiones y su grado de afección.Resultados. Se trabajaron ocho muestras de tejido de M. musculus y siete de R. rattus. Se encontraron nidos parasitarios en siete del total de las muestras: en 3 de las 8 de M. musculus y en 4 de las 7 de R. rattus. Se observaron infiltrados inflamatorios en todas las muestras. Otras lesiones fueron la degeneración de las fibras cardiacas (8/15), la congestión de los vasos sanguíneos (6/15) y la necrosis (5/15).Discusión. Las lesiones observadas están descritas en los modelos animales experimentales y en los humanos con tripanosomiasis americana. Los infiltrados inflamatorios se han descrito como la lesión más significativa en los humanos y en los reservorios en la etapa crónica de la enfermedad.Conclusión. Las lesiones observadas están asociadas con la infección con T. cruzi, lo cual confirma que los roedores estudiados son reservorios de este parásito.
DEVELOPMENT OF ABSORBENT TECHNOLOGY FOR OIL SPILL RECOVERY AND CLEANUP IN ARCTIC ENVIRONMENT
Authors: Nam Changwoo , Li Houxiang , Chung T.C. Mike 
Published: September 2019

ABSTRACT 2017-076 In this paper, we discuss a new class of i-PetroGel oil-superabsorbent technology that has shown a potential solution to the oil spill recovery and cleanup in arctic environments, based on the laboratory tests at Penn State and an open tank test at Ohmsett. This i-PetroGel material is formed by polyolefin polymers that are petroleum downstream products with similar oleophilic and hydrophobic properties of oil molecules. Apart from many oil sorbents based on adsorption, i-PetroGel absorbs oil by absorption (similar to Hydrogel absorbing aqueous solutions) and swells to a large volume. During Ohmsett testing, i-PetroGel flakes spread on top of the affected area showed effective transformation of Alaska North Slope (ANS) oil into a floating gel on the seawater surface, which was effectively recovered by an oleophilic drum skimmer and pumped to a storage tank. The recovered ANS oil-swelled adducts, containing <0.1 wt% water, exhibit similar distillation characteristics as the original ANS oil. Overall, this i-PetroGel technology could potentially provide a comprehensive solution for combating oil spills, with the goal to dramatically reduce the environmental impacts from oil spills and help recover one of the most precious natural resources. i-PetroGel exhibits a combination of desirable properties. ✓ High oil absorption capacity about 35–40 times by weight at 3 and 25 °C. ✓ Suitable to a broad range of hydrocarbons, including complex crude oils, refined oil products (gasolines, diesels, heating oils, etc.), and solvents (toluene, benzene, etc.). ✓ Fast kinetics in capturing the spilled oil. ✓ No detectable water absorption in i-PetroGel. ✓ The resulting oil/i-PetroGel adducts floating on water surface are recovered by skimmer. ✓ The recovered oil/i-Petrogel adducts can be refined as crude oil through standard refining processes. ✓ Cost effective. ✓ No secondary pollution.
Interaction of gas bubbles and oil droplets in subsea oil and gas blowouts – a new development of VDROP-J model.
Authors: Zhao Lin , Boufadel Michel C. , Gao Feng , King Thomas , Robinson Brian , Lee Kenneth 
Published: September 2019

Abstract (2017-194) The presence of methane bubbles in the oil and gas blowout could greatly reduce the oil droplet sizes. Bubbles tend to introduce energy into the system and separate oil droplets from each other. The interaction of oil droplets and gas bubbles in the near field of a blowout was investigated numerically using the VDROP-J model, whose droplet size distribution (DSD) was thoroughly calibrated. For this purpose, a new numerical scheme has been developed in VDROP-J to account for the interaction of gas bubbles and oil droplets in the blowout, giving simultaneous simulation of bubble and droplet size distribution along the discharged plume. Validation shows improvement of the model compared with the one without considering the gas bubble and oil droplet interactions. Effects of gas volume fraction on the droplet formation are also investigated. This new development will enhance the knowledge in subsea oil and gas blowouts.