bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual Antibacterial and Anticancer Activity of 4-Benzoyl-1-dichlorobenzoylthiosemicarbazide Derivatives
Authors: Kapron Barbara , Czarnomysy Robert , Paneth Agata , Wujec Monika , Bielawski Krzysztof , Bielawska Anna , Swiatek Lukasz , Rajtar Barbara , Polz-Dacewicz Malgorzata , Plech Tomasz 
Published: July 2018

Objective/Method: A group of 4-benzoyl-1-dichlorobenzoylthiosemicarbazides endowed
with antibacterial activity was evaluated for its cytotoxic properties against breast cancer cells (MCF-7,
MDA-MB-231) and head and neck squamous cell carcinomas (FaDu, SCC-25). Cytotoxicity of the investigated
compounds was measured using MTT and [3H]-thymidine incorporation bioassays.

Result:
1-(2,3-Dichlorobenzoyl)-4-(2-methylbenzoyl)thiosemicarbazide (TA-4), 1-(2,4-dichlorobenzoyl)-
4-(2-methylbenzoyl)thiosemicarbazide (TA-18), and 1-(2,4-dichlorobenzoyl)-4-(4-nitrolbenzoyl)-
thiosemicarbazide (TA-20) were found to possess anticancer activity equipotent or even stronger than
that of reference drug – etoposide. In order to clarify the molecular mode of action of the mentioned
compounds, the relaxation assay kit for human DNA topoisomerase II was used. It turned out that reduction
of viability of cancer cells was a result of inhibition of human DNA topoII. Molecular docking
studies proved that 4-benzoyl-1-dichlorobenzoylthiosemicarbazides strongly interact with DNAdependent
subunit of that enzyme.
Modal sosial dan media sosial pada masyarakat cyber di Desa Melung, Kabupaten Banyumas
Authors: Malik Imam , Dwiningrum Siti Irene Astuti 
Published: July 2018

Penelitian ini bertujuan untuk mendeskripsikan: (1) penggunaan media sosial, (2) memetakan modal sosial, dan (3) menganalisis peran modal sosial dalam membentuk pola penggunaan media sosial yang ada pada masyarakat cyber di desa Melung. Penelitian ini menggunakan pendekatan kualitatif dengan kajian fenomenologi. Unit analisisnya adalah masyarakat desa Melung. Data primer diperoleh dari hasil wawancara terhadap berbagai kategori informan di desa Melung. Analisis data dilakukan dengan mengumpulkan data, mereduksi data, dan verifikasi yang dilakukan secara bertahap. Hasil penelitian menunjukan bahwa media sosial di desa Melung digunakan sebagai media promosi bagi masyarakat untuk mempromosikan desa mereka sebagai desa wisata. Keberadaan media sosial dan pemanfaatanya sebagai media promosi didukung oleh kepercayaan masyarakat terhadap kepala desa. Kpercayaan masyarakat terhadap kepala desa berperan sebagai modal sosial yang ada di desa Melung. Keberadaan modal sosial yang dimiliki oleh masyarakat berperan sebagai pembentuk masyarakat cyber dan juga faktor utama terealisasinya pembangunan jaringan interenet di desa Melung.Kata kunci: media sosial, masyarakat cyber, modal sosial SOCIAL CAPITAL AND SOCIAL MEDIA IN CYBER SOCIETY IN THE MELUNG VILLAGE, REGENCY OF BANYUMASAbstractThis study aims to describe: (1) the use of social media, (2) mapping social capital, and (3) analyzing the role of social capital in shaping the patterns of using social media that exist in the cyber community in Melung village. This research used qualitative approach with phenomenology study. The unit of analysis is Melung village society. Primary data were obtained from interview on various categories of informants in Melung village. Data analysis was done by collecting data, reducing data, and verification which done in stages. The results showed that social media in Melung village was used as a media campaign for the community to promote their village as a tourist village. The existence of social media and their use was supported by the public's trust in the village head. The public's trust in the village head served as a social capital in the village Melung. The role of social capital that exists was as reinforcement in shaping the cyber community and the main factor of the realization, construction of the interenet network in the Melung village.Keywords: social media, cyber society, social capital
Pendidikan karakter dalam Serat Tripama karya Mangkunegara IV
Authors: Wardhani Novia Wahyu , Muhadjir Noeng 
Published: July 2018

Tujuan penelitian ini adalah untuk menggali kembali nilai-nilai kearifan lokal masa lalu seperti dalam Serat Tripama Karya Mangkunegara IV sehingga dapat dibedakan mana yang harus diteladani dan mana yang tidak tetapi dapat dijadikan materi analisis nilai dalam pembelajaran. Metode yang digunakan adalah metode kualitatif dengan pendekatan interpretasi, hermeneutik, dan verstehen. Teknik analisis yang digunakan adalah analisis data model interaktif yang terdiri dari pengumpulan data, reduksi data, penyajian data, dan verifikasi. Hasil penelitian ini adalah tidak semua nilai dapat dijadikan sumber keteladanan bagi pembentukan karakter peserta didik. Nilai yang dapat diteladani adalah nilai niat yang baik, pengabdian yang tulus disertai dengan usaha, dan kerelaan berkorban pada kebenaran.Kata kunci: pendidikan karakter, serat tripama, Mangkunegara IV CHARACTER EDUCATION IN SERAT TRIPAMA BY MANGKUNEGARA IVAbstractThe purpose of this research is to dig again values local knowledge the past as work in the Serat Tripama Mangkunegara iv so as to be distinguishable which one to role models all and which ones have not but can be used as matter analysis value in learning. Methods used was a qualitative methodology with the approach interpretation, hermeneutic, and verstehen. Technique the analysis used is interactive data analysis model consisting of data collection, reduction data, presentation of data, and verification. The result of this research is not all value can be used as a source of exemplary for the establishment of character school tuition. Value that can be role models all is the value of good reasons, devotion sincere accompanied by business, and mutual consent sacrifice to the truth.Keywords: character education, serat tripama, Mangkunegara IV
Penanaman nilai-nilai religius di madrasah aliyah Nahdlatul Wathan Pancor Lombok Timur Nusa Tenggara Barat
Authors: Manan Abd. Latif , Kuntoro Sodiq A. , Sudrajat Ajat 
Published: July 2018

Penelitian ini dimaksudkan untuk; (1) mengetahui dan mengkaji upaya penanaman nilai-nilai religius di Madrasah Aliyah Nahdlatul Wathan Pancor Lombok Timur; (2) menganalisis faktor-faktor penghambat pengembangan nilai-nilai religius di Madrasah Aliyah Nahdlatul Wathan Pancor Lombok Timur. Metode yang digunakan dalam penelitian ini adalah metode studi kasus dengan pendekatan kualitatif. Penelitian dilakukan di Madrasah Aliyah Nahdlatul Wathan Kelurahan Pancor Kabupaten Lombok Timur Provinsi Nusa Tenggara Barat. Data diperoleh melalui observasi, wawancara, dan dokumentasi. Teknik analisis data menggunakan reduksi data, display data, penarikan serta pengujian kesimpulan. Hasil penelitian menunjukkan bahwa: (1) Penanaman nilai-nilai religius di Madrasah Aliyah Nahdlatul Wathan Pancor ditempuh melalui beberapa upaya, yakni: (a) melalui kegiatan belajar mengajar di dalam kelas maupun di luar kelas melalui kegiatan keagamaan; (b) menggunakan berbagai strategi; serta (c) menjalin kerja sama sekolah dengan orang tua siswa; (2) faktor-faktor yang mempengaruhi penanaman nilai-nilai religius berasal dari faktor guru, siswa, dan orang tua siswa.Kata kunci: nilai, religius, perilaku keagamaan siswa INCULCATING RELIGIOUS VALUES IN MADRASAH ALIYAH NAHDLATUL WATHAN PANCOR EAST LOMBOKAbstractThis research is intended for: (1) knowing and reviewing the effort of inculcating religious values in Madrasah Aliyah Nahdlatul Wathan Pancor East Lombok; (2) analyzing the factors that hamper the Inculcating of religious values in Madrasah Aliyah Nahdlatul Wathan Pancor East Lombok. The method used in this research is case study method with qualitative approach. The research was conducted at Madrasah Aliyah Nahdlatul Wathan, Pancor Sub-District, East Lombok Regency, West Nusa Tenggara Province. Data were obtained through observation, interviews, and documentation. Data analysis techniques using data reduction, data display, and drawing and verifying conclusions. The results showed that: (1) inculcating of religious values in Madrasah Aliyah Nahdlatul Wathan Pancor taken through several efforts, namely: (a) through teaching and learning activities in the classroom or outside the classroom through religious activities; (b) using various strategies, and (c) establish school cooperation with parents of students; (2) factors influencing the inculcating of religious values are derived from teachers, students, and parents.Keywords: values, religious, student’s religious behavior
A Patient-Facing Diabetes Dashboard Embedded in a Patient Web Portal: Design Sprint and Usability Testing
Authors: Martinez William , Threatt Anthony L , Rosenbloom S Trent , Wallston Kenneth A , Hickson Gerald B , Elasy Tom A 
Published: July 2018

Background
Health apps and Web-based interventions designed for patients with diabetes offer novel and scalable approaches to engage patients and improve outcomes. However, careful attention to the design and usability of these apps and Web-based interventions is essential to reduce the barriers to engagement and maximize use.

Objective
The aim of this study was to apply design sprint methodology paired with mixed-methods, task-based usability testing to design and evaluate an innovative, patient-facing diabetes dashboard embedded in an existing patient portal and integrated into an electronic health record.

Methods
We applied a 5-day design sprint methodology developed by Google Ventures (Alphabet Inc, Mountain View, CA) to create our initial dashboard prototype. We identified recommended strategies from the literature for using patient-facing technologies to enhance patient activation and designed a dashboard functionality to match each strategy. We then conducted a mixed-methods, task-based usability assessment of dashboard prototypes with individual patients. Measures included validated metrics of task performance on 5 common and standardized tasks, semistructured interviews, and a validated usability satisfaction questionnaire. After each round of usability testing, we revised the dashboard prototype in response to usability findings before the next round of testing until the majority of participants successfully completed tasks, expressed high satisfaction, and identified no new usability concerns (ie, stop criterion was met).

Results
The sample (N=14) comprised 5 patients in round 1, 3 patients in round 2, and 6 patients in round 3, at which point we reached our stop criterion. The participants’ mean age was 63 years (range 45-78 years), 57% (8/14) were female, and 50% (7/14) were white. Our design sprint yielded an initial patient-facing diabetes dashboard prototype that displayed and summarized 5 measures of patients’ diabetes health status (eg, hemoglobin A1c). The dashboard used graphics to visualize and summarize health data and reinforce understanding, incorporated motivational strategies (eg, social comparisons and gamification), and provided educational resources and secure-messaging capability. More than 80% of participants were able to successfully complete all 5 tasks using the final prototype. Interviews revealed usability concerns with design, the efficiency of use, and content and terminology, which led to improvements. Overall satisfaction (0=worst and 7=best) improved from the initial to the final prototype (mean 5.8, SD 0.4 vs mean 6.7, SD 0.5).

Conclusions
Our results demonstrate the utility of the design sprint methodology paired with mixed-methods, task-based usability testing to efficiently and effectively design a patient-facing, Web-based diabetes dashboard that is satisfying for patients to use.
Feasibility Randomized Controlled Trial of ImpulsePal: Smartphone App–Based Weight Management Intervention to Reduce Impulsive Eating in Overweight Adults (Preprint)
Authors: van Beurden Samantha B , Smith Jane R , Lawrence Natalia S , Abraham Charles , Greaves Colin J 
Published: July 2018

BACKGROUND

ImpulsePal is a theory-driven (dual-process), evidence-informed, and person-centered smartphone app intervention designed to help people manage impulsive processes that prompt unhealthy eating to facilitate dietary change and weight loss.

OBJECTIVE

The aims of this study were to (1) assess the feasibility of trial procedures for evaluation of the ImpulsePal intervention, (2) estimate standard deviations of outcomes, and (3) assess usability of, and satisfaction with, ImpulsePal.

METHODS

We conducted an individually randomized parallel two-arm nonblinded feasibility trial. The eligibility criteria included being aged ≥16 years, having a body mass index of ≥25 kg/m2, and having access to an Android-based device. Weight was measured (as the proposed primary outcome for a full-scale trial) at baseline, 1 month, and 3 months of follow-up. Participants were randomized in a 2:1 allocation ratio to the ImpulsePal intervention or a waiting list control group. A nested action-research study allowed for data-driven refinement of the intervention across 2 cycles of feedback.

RESULTS

We screened 179 participants for eligibility, and 58 were randomized to the intervention group and 30 to the control group. Data were available for 74 (84%, 74/88) participants at 1 month and 67 (76%, 67/88) participants at 3 months. The intervention group (n=43) lost 1.03 kg (95% CI 0.33 to 1.74) more than controls (n=26) at 1 month and 1.01 kg (95% CI −0.45 to 2.47) more than controls (n=43 and n=24, respectively) at 3 months. Feedback suggested changes to intervention design were required to (1) improve receipt and understanding of instructions and (2) facilitate further engagement with the app and its strategies.

CONCLUSIONS

The evaluation methods and delivery of the ImpulsePal app intervention are feasible, and the trial procedures, measures, and intervention are acceptable and satisfactory to the participants.

CLINICALTRIAL

International Standard Randomized Controlled Trial Number (ISRCTN): 14886370; http://www.isrctn.com/ISRCTN14886370 (Archived by WebCite at http://www.webcitation.org/76WcEpZ51)
Cost of Dialysis Therapy by Modality in Manitoba
Authors: Beaudry Alain , Ferguson Thomas W. , Rigatto Claudio , Tangri Navdeep , Dumanski Sandi , Komenda Paul 
Published: July 2018

Background and objectives
The prevalence of ESKD is increasing worldwide. Treating ESKD is disproportionately costly in comparison with its prevalence, mostly due to the direct cost of dialysis therapy. Here, we aim to provide a contemporary cost description of dialysis modalities, including facility-based hemodialysis, peritoneal dialysis, and home hemodialysis, provided with conventional dialysis machines and the NxStage System One.

Design, setting, participants, & measurements
We constructed a cost-minimization model from the perspective of the Canadian single-payer health care system including all costs related to dialysis care. The labor component of costs consisted of a breakdown of activity-based per patient direct labor requirements. Other costs were taken from statements of operations for the kidney program at Seven Oaks General Hospital (Winnipeg, Canada). All costs are reported in Canadian dollars.

Results
Annual maintenance expenses were estimated as $64,214 for in-center facility hemodialysis, $43,816 for home hemodialysis with the NxStage System One, $39,236 for home hemodialysis with conventional dialysis machines, and $38,658 for peritoneal dialysis. Training costs for in-center facility hemodialysis, home hemodialysis with the NxStage System One, home hemodialysis with conventional dialysis machines, and peritoneal dialysis are estimated as $0, $16,143, $24,379, and $7157, respectively. The threshold point to achieve cost neutrality was determined to be 9.7 months from in-center hemodialysis to home hemodialysis with the NxStage System One, 12.6 months from in-center hemodialysis to home hemodialysis with conventional dialysis machines, and 3.2 months from in-center hemodialysis to peritoneal dialysis.

Conclusions
Home modalities have lower maintenance costs, and beyond a short time horizon, they are most cost efficient when considering their incremental training expenses.

Podcast
This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2018_07_18_CJASNPodcast_18_8_F.mp3
Penentuan Kriteria Evaluasi Kinerja Widyaiswara Menggunakan Nominal Group Technique
Authors: Rohmatulloh R , Kusumastuti Retno , Shiddiq Julian Ambassadur 
Published: July 2018

The role of competent trainers as an important part in creating an organizing system of the qualified training program. To improve the competencyof trainers to match the expected criteria, trainers evaluation of performance as the basic tools are needed. The purpose of this study is to determine the criteria or parameters that used in evaluating trainers performance. Determination of criteria is using the groupdecision-making techniques, namely nominal group technique (NGT). The NGT participants are trainer and planner. Successful criteria in consensus are established by the suitability of substance with the competence attended training, training participant satisfaction in classroom teaching ability, and the achievement of credit points. The criteria can be used as a reference for the evaluation and the results can be used for the appropriate competencies development that suitable with trainers requirement. The use of NGT is more effective to generate many ideas and determination of evaluation criteria.
A Content Analysis of the Privacy Policies of Cloud Computing Services
Authors: Gao Lei , Brink Alisa G. 
Published: July 2018

ABSTRACT
Cloud computing is increasingly popular across all sectors and offers users unparalleled scalability, elasticity, and flexibility. However, the rapid transition toward cloud computing has raised privacy and confidentiality concerns. Cloud service providers can access users' data, and private information may be accidentally or deliberately disclosed or used for unauthorized purposes. Privacy policies are intended to provide users with information about privacy practices and their privacy options. This study performs content analysis of the privacy policies of 47 cloud service providers who offer services to business users. This analysis identifies what information is collected and why, to whom the information is disclosed, and what measures are in place for data security, data retention, and data complaints. Additionally, we investigate the readability, uncertainty language, and linguistic tone of cloud service privacy policies. Our results offer implications for cloud service users, providers, and policymakers, and provide directions for future research.
Data Availability: Data are available upon request.
An Empirical Study of Regional Mutual Funds’ Diversification Value
Authors: Rodriguez Javier 
Published: July 2018

This article studies three samples of United States-based regional mutual funds from the Asia-Pacific, Europe, and Latin America, to assess whether higher fund diversification translates into higher diversification values to fund shareholders. To measure mutual funds’ portfolio diversification, we implement a modified Herfindahl index. To assess diversification values we employ a methodology that considers Sharpe ratio funds and its correlation with existent portfolios. We found that Asian-Pacific funds are the most diversified, whereas European funds provide the highest diversification value to fund shareholders. The correlation between fund diversification and diversification value is positive only in the case of Asian-Pacific funds. To the best of our knowledge, the relation between portfolio diversification and diversification value of regional mutual funds has not yet been addressed in the literature.
REVIEW: British bomb legacy lingers in the islands
Authors: Duffield Lee 
Published: July 2018

Grappling with the H Bomb, by Nic McLellan. Canberra: ANU Press, 2017. 408 pages. ISBN 9781760461379/9781760461386.
NIC McLELLAN’s Grappling with the H Bomb, is an adroit and readable treatment of the story of the British nuclear testing programme predominantly in the South Pacific islands. Its chief focus is the series of nine British nuclear tests at Malden and Christmas (Kiritimati) Islands between May 1957 and September 1958. They were then part of the Gilbert and Ellice Islands Colony (GEIC), which was divided into Kiribati and Tuvalu at independence. Malden and Christmas (Kiritimati) Islands are now part of Kiribati.
REVIEW: Noted: Perfect media research text for undergraduates
Authors: Thomson Christopher 
Published: July 2018

Digital Media and Society, by Simon Lindgren. London: Sage, 2017. 328 pages. ISBN 9781473925014
FROM the ‘flamethrower squirrel’ meme chosen for its cover to the many box-outs that define key questions, concepts and exercises for thinking, Simon Lindgren’s Digital Media and Society is a punchy, engaging text pitched perfectly for undergraduates and others seeking an accessible introduction to contemporary media research.
REVIEW: Noted: Jungle hostage to photojournalist
Authors: Abcede Del 
Published: July 2018

Françoise Huguier: 100 Photos for Press Freedom, edited by Perribe Daubas. Paris: Reporters Without Borders (RSF). 2018. 134 pages. ISBN 978-2-36220-050-9.
THIS is yet another extraordinary ‘100 Photos for Press Freedom’ album from Reporters Sans Frontières (RSF), this time with a focus on the ‘indignation of women against male predation and domination’ (p. 139), as essayist Aude Bassonville notes in one of the accompanying articles. The collection of photos mostly feature the work of French photographer Françoise Huguier, who is described by the editors as chareacteristic of the best attributes of a photojournalist – ‘curiosity, intensity, desire and a love for life’.
A tale of two statues: Contemporary conflict reporting constraints and the Battle of Baghdad
Authors: Ellmers Stephen 
Published: July 2018

Although television conflict reporting has usually been limited by risks to journalists’ safety, the death throes of Baathist Iraq in April 2003 provided viewers with a unique opportunity to vicariously witness the fall of a large modern city. Yet if the iconic moment of the Second Gulf War came when Saddam Hussein’s statue in Firdos Square was toppled, then it was at the expense of another image event which unfolded earlier a short distance away. Because the US military’s violent destruction of the equestrian statue close to the ‘Hands of Victory’ monument better encapsulates the conflict than the sterile bloodless ‘cakewalk’ description it’s usually labelled with. This article shows how the tale of these two statues is also in some ways the tale of two Fox News correspondents, and how an alienation from military service conditions and methods can leave reporters and their audiences with no sense of what the participants on their screens endured in order to reach Baghdad; or what they had also inflicted upon others. In retrospect, the circumstances which allowed one Fox reporter to provide the world with what might have been its first taste of live, unedited combat footage seem more like an accidental success than the result of systemic best practices. Especially when this network and even its most credible host remain committed to ensuring a particular partisan perspective dominates all their broadcasts.