bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Quality Factors of Surface Lattice Resonances in Plasmonic Arrays of Nanoparticles
Authors: Le‐Van Quynh , Zoethout Erwin , Geluk Erik‐Jan , Ramezani Mohammad , Berghuis Matthijs , Gómez Rivas Jaime 
Published: January 2019

AbstractKey in the application of plasmonics is the realization of low loss or high quality (Q) factor resonances. Nanoparticle arrays are systems capable of sustaining remarkably high Q‐factor resonances through the hybridization of plasmonic and photonic modes, known as surface lattice resonances (SLRs). SLRs result from the coupling of localized surface plasmon resonances (LSPRs) to in‐plane orders of diffraction known as Rayleigh anomalies (RAs). To date, the highest Q‐factors have been achieved with the (±1, 0) diffraction orders. However, these Q‐factors are highly sensitive to the angle of excitation. Here, a strategy is presented to generate high Q‐factor SLRs with low dispersion by coupling LSPRs to the (0, ±1) diffraction orders. 2D arrays of silver nanoparticles are investigated experimentally and numerically, and it is shown that the Q‐factor of SLRs critically depends on the quality of the metal film, the detuning between RAs and LSPRs, and the absorption of adhesive layer used between the substrate and the metallic nanoparticles. These silver nanoparticle arrays can achieve Q‐factors higher than 330 in the visible range. These extraordinarily high Q‐factors could be increased to values above 1500 if no adhesive layer is used, which could significantly improve sensors and enhance nonlinearities in plasmonic systems.
Enzyme Cascade Reactions for the Biosynthesis of Long Chain Aliphatic Amines from Renewable Fatty Acids
Authors: Lee Da‐Som , Song Ji‐Won , Voß Moritz , Schuiten Eva , Akula Ravi Kumar , Kwon Yong‐Uk , Bornscheuer Uwe , Park Jin‐Byung 
Published: January 2019

AbstractEnzyme cascade reactions for the synthesis of long chain aliphatic amines such as (Z)‐12‐aminooctadec‐9‐enoic acid, 10‐ or 12‐aminooctadecanoic acid, and 10‐amino‐12‐hydroxyoctadecanoic acid from renewable fatty acids were investigated. (Z)‐12‐aminooctadec‐9‐enoic acid was produced from ricinoleic acid ((Z)‐12‐hydroxyoctadec‐9‐enoic acid) via (Z)‐12‐ketooctadec‐9‐enoic acid with a conversion of 71% by a two‐step in vivo biotransformation involving a long chain secondary alcohol dehydrogenase (SADH) from Micrococcus luteus and a variant of the amine transaminase (ATA) from Vibrio fluvialis. 10‐Aminooctadecanoic acid was prepared from oleic acid ((Z)‐octadec‐9‐enoic acid) via 10‐hydroxyoctadecanoic acid and 10‐ketooctadecanoic acid by an in vivo three‐step biocatalysis reaction involving not only the SADH and ATA variants, but also a fatty acid double bond hydratase (OhyA) from Stenotrophomonas maltophilia.10‐Aminooctadecanoic acid was produced at a total rate of 4.4 U/g dry cells with a conversion of 87% by recombinant Escherichia coli expressing the SADH and ATA variants, and OhyA simultaneously. In addition, bulky aliphatic amines could also be produced by the isolated enzymes (i. e., the SADH, the ATA variants, and a nicotinamide adenine dinucleotide (NADH) oxidase from Lactobacillus brevis) with methylbenzylamine or benzylamine as amino donor. This study thus contributes to the biosynthesis of long chain aliphatic amines having two large substituents next to the amine functionality.magnified image
Sustainable Liquid Luminescent Solar Concentrators
Authors: Frias Ana R. , Correia Sandra F. H. , Martins Margarida , Ventura Sónia P. M. , Pecoraro Edison , Ribeiro Sidney J. L. , André Paulo S. , Ferreira Rute A. S. , Coutinho João A. P. , Carlos Luís D. 
Published: January 2019

AbstractLuminescent solar concentrators (LSCs) are photovoltaic (PV) complementary devices to overcome the mismatch between the Si‐based PV cells, response and the solar spectrum, allowing PV urban integration. Challenges for the luminescent layer include the use of abundant and sustainable natural organic molecules. Here, LSCs composed of a glass container and based on bundles of cylindrical hollow‐core plastic optical fibers filled with aqueous solutions of R‐phycoerythrin (R‐PE), extracted from Gracilaria sp. algae are presented. The R‐PE solutions absorb in the UV/visible spectral range (300–550 nm) and convert this radiation into red‐emission (550–700 nm) with a maximum absolute quantum yield of ≈0.39. In this work, LSCs with distinct geometries are reported, in which the R‐PE emission yields optical conversion efficiency values up to ≈6.88% and ≈4.74% for a planar device and for a bundle of cylindrical LSCs, respectively, which are the largest values known for liquid‐based LCSs using sustainable emitting centres. Moreover, the coupling of the LSCs to commercial Si‐based PV devices yields power conversion efficiency values of ≈0.27% (planar) and ≈23.03 × 10−3%, (bundle). These values illustrate the potential of this approach for the development of natural‐based LSCs meeting the requirements of reliable, sustainable, and competitive energy systems.
A Protein‐Based, Water‐Insoluble, and Bendable Polymer with Ionic Conductivity: A Roadmap for Flexible and Green Electronics
Authors: Kadumudi Firoz Babu , Jahanshahi Mohammadjavad , Mehrali Mehdi , Zsurzsan Tiberiu‐Gabriel , Taebnia Nayere , Hasany Masoud , Mohanty Soumyaranjan , Knott Arnold , Godau Brent , Akbari Mohsen , Dolatshahi‐Pirouz Alireza 
Published: January 2019

AbstractProteins present an ecofriendly alternative to many of the synthetic components currently used in electronics. They can therefore in combination with flexibility and electroactivity uncover a range of new opportunities in the field of flexible and green electronics. In this study, silk‐based ionic conductors are turned into stable thin films by embedding them with 2D nanoclay platelets. More specifically, this material is utilized to develop a flexible and ecofriendly motion‐sensitive touchscreen device. The display‐like sensor can readily transmit light, is easy to recycle and can monitor the motion of almost any part of the human body. It also displays a significantly lower sheet resistance during bending and stretching regimes than the values typically reported for conventional metallic‐based conductors, and remains fully operational after mechanical endurance testing. Moreover, it can operate at high frequencies in the kilohertz (kHz) range under both normal and bending modes. Notably, our new technology is available through a simple one‐step manufacturing technique and can therefore easily be extended to large‐scale fabrication of electronic devices.
Refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis: “2019 Update on Diagnosis, Risk‐stratification, and Management”
Authors: Patnaik Mrinal M. , Tefferi Ayalew 
Published: January 2019

Disease OverviewRing sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. Two myeloid neoplasms defined by the presence of RS, include refractory anemia with ring sideroblasts (RARS), now classified under myelodysplastic syndromes with RS (MDS‐RS) and RARS with thrombocytosis (RARS‐T); now called myelodysplastic/myeloproliferative neoplasm with RS and thrombocytosis (MDS/MPN‐RS‐T).DiagnosisMDS‐RS is a lower‐risk MDS, with single or multilineage dysplasia (SLD/MLD), <5% bone marrow (BM) blasts and ≥ 15% BM RS (≥5% in the presence of SF3B1 mutations). MDS/MPN‐RS‐T, now a formal entity in the MDS/MPN overlap syndromes, has diagnostic features of MDS‐RS‐SLD, along with a platelet count ≥450 × 10(9)/L and large atypical megakaryocytes.Mutations and KaryotypeMutations in SF3B1 are seen in ≥80% of patients with MDS‐RS‐SLD and MDS/MPN‐RS‐T, and strongly correlate with the presence of BM RS; MDS/MPN‐RS‐T patients also demonstrate JAK2V617F, ASXL1, DNMT3A, SETBP1, and TET2 mutations. Cytogenetic abnormalities are uncommon in both.Risk stratificationMost patients with MDS‐RS‐SLD are stratified into lower‐risk groups by the revised‐IPSS. Disease outcome in MDS/MPN‐RS‐T is better than that of MDS‐RS‐SLD, but worse than that of essential thrombocythemia. Both diseases have a low risk of leukemic transformation.TreatmentAnemia and iron overload are complications seen in both and are managed similar to lower‐risk MDS and MPN. The advent of luspatercept, a first‐in‐class erythroid maturation agent will tremendously boost the ability to manage anemia. Aspirin therapy is reasonable in MDS/MPN‐RS‐T, especially in the presence of JAK2V617F, but the value of platelet‐lowering drugs remains uncertain.
STEFs: Activated Vinylogous Protein‐Reactive Electrophiles
Authors: Hansen Bente K. , Loveridge Christopher J. , Thyssen Stine , Wørmer Gustav J. , Nielsen Andreas D. , Palmfeldt Johan , Johannsen Mogens , Poulsen Thomas B. 
Published: January 2019

AbstractReported here is the synthesis of a class of semi‐oxamide vinylogous thioesters, designated STEFs, and the use of these agents as new electrophilic warheads. This work includes preparation of simple probes that contain this reactive motif as well as its installation on a more complex kinase inhibitor scaffold. A key aspect of STEFs is their reactivity towards both thiol and amine groups. Shown here is that amine conjugations in peptidic and proteinogenic samples can be facilitated by initial, fast conjugation to proximal thiol residues. Evidence that both the selectivity and the reactivity can be tuned by the structure of STEFs is provided, and given the unique ability of this functionality to conjugate by an addition‐elimination mechanism, STEFs are electrophilic warheads that could find broad use in chemical biology.
Ultra‐Fast Synthesis of Multivalent Radical Nanoparticles by Ring‐Opening Metathesis Polymerization‐Induced Self‐Assembly
Authors: Le Dao , Dilger Marco , Pertici Vincent , Diabaté Silvia , Gigmes Didier , Weiss Carsten , Delaittre Guillaume 
Published: January 2019

AbstractWe report the straightforward, time‐efficient synthesis of radical core–shell nanoparticles (NPs) by polymerization‐induced self‐assembly. A nitroxide‐containing hydrophilic macromolecular precursor was prepared by ring‐opening metathesis copolymerization of norbornenyl derivatives of TEMPO and oligoethylene glycol and was chain‐extended in situ with norbornene in ethanolic solution, leading to simultaneous amphiphilic block copolymer formation and self‐assembly. Without any intermediate purification from the monomers to the block copolymers, radical NPs with tunable diameters ranging from 10 to 110 nm are obtained within minutes at room temperature. The high activity of the radical NPs as chemoselective and homogeneous, yet readily recyclable catalysts is demonstrated through oxidation of a variety of alcohols and recovery by simple centrifugation. Furthermore, the NPs show biocompatibility and antioxidant activity in vitro.
Composite latex production with high solid content
Authors: Delibaş Ali , Yıldız Ufuk , Tauer Klaus 
Published: January 2019

ABSTRACTPoly(methyl methacrylate‐co‐butyl acrylate) (PMMA‐co‐PBA) and poly(sytrene‐co‐butyl acrylate) (PSt‐co‐PBA) latexes in which solid content (SC) varied from 20% up to 40 wt % armored with laponite clay have been successfully synthesized using a simple method, which does not require modification of the clay particles prior to polymerization. Incorporation of quite high amounts of laponite nanoparticles into PMMA‐co‐PBA and PSt‐co‐PBA latexes with a certain amount of solids content was achieved. The nanocomposite latexes and polymer samples were characterized using Fourier transform infrared (FTIR) spectroscopy in attenuated total reflectance (ATR) mode, dynamic light scattering (DLS), X‐ray diffraction (XRD), transmission electron microscopy (TEM), thermal gravimetric analysis (TGA), differential scanning calorimetry (DSC), contact angle, zeta potential, viscosimetry and analytical ultracentrifuge (AUC). Zeta potential values showed that stable latex was obtained and precipitation problem of the nanoparticles in the latex was not seen during the storage. Obtained nanocomposite latex showed fine particle size between 88 and 160 nm. TEM images and XRD results pointed out that the exfoliated nanocomposite structure for latexes was obtained. DSC analyzes showed that the glass‐transition temperature (T
g) values of nanocomposite films decreased slightly compared with those of pure (PMMA‐co‐PBA) films. Mechanical properties of laponite clay armored PMMA‐co‐PBA were tested and compared with those of pure PMMA‐co‐PBA, indicating that incorporated the Young's modulus and tensile strength are also improved to a noticeable extent after the incorporation of laponite. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47423.
Effect of modified ZnO nanoparticle on the properties of polylactide ultrafine fibers
Authors: Ryu Yeon Sung , Kim Ick‐Soo , Kim Seong Hun 
Published: January 2019

ABSTRACTZinc oxide (ZnO) was modified with hexadecyltrimethoxysilane (HDTMS) to obtain hydrophobicity and used to reinforce polylactide (PLA), an environmentally friendly polymer. The PLA/HDTMS‐modified ZnO (m‐ZnO) nanocomposite prepared by adding m‐ZnO to the PLA matrix was fabricated into ultrafine fiber using electrospinning. Neat PLA and PLA/ZnO were used for comparisons. Structural analysis of the nanoparticles proved that the ZnO was modified successfully, and that the modification affected dispersibility and hydrophobicity, as observed by morphological, visual, and water repellency tests. The morphological analysis of the electrospun ultrafine fabrics under suitable conditions confirmed that the nanoparticles were well incorporated, and the desired functional changes were observed. Measurement of water repellency and mechanical, thermal properties were used to analyze the effect of nanoparticle modification and composition on fabrics. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47446.
Coupled analysis on heterogeneous oxidative aging and viscoelastic performance of rubber based on multi‐scale simulation
Authors: Zhi Jieying , Wang Qinglin , Zhang Mengjie , Li Manjia , Jia Yuxi 
Published: January 2019

ABSTRACTAn oxidative aging‐viscoelastic constitutive model was established to study the coupled heterogeneous oxidation and viscoelastic performance of rubber during aging process. The basic elasticity and viscoelasticity of rubber materials were comparatively considered as the function of ongoing aging. The dynamic compression process of natural rubber at different aging times was analyzed by the finite element method. And then the effects of oxygen uptake, diffusion, and oxidative reactions on the dynamic viscoelasticity of rubber were analyzed. The permeability of the oxygen in natural rubber was determined by means of molecular dynamics simulation. The results reveal that the heterogeneous degradation caused by diffusion‐limited oxidation can lead to a complex stress distribution in the natural rubber specimen under dynamic loading condition; the relaxation time and the energy dissipation of the rubber specimen also increased after aging. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2019,136, 47452
HPAM‐g‐PEOPPO: Rheological modifiers in aqueous media of high temperature and high ionic strength
Authors: de Lima Bruna Luiza Batista , Marques Nívia do Nascimento , Villetti Marcos Antônio , Balaban Rosangela de Carvalho 
Published: January 2019

ABSTRACTPartially hydrolyzed polyacrylamide (HPAM) is widely used as thickener in enhanced oil recovery (EOR), but the high temperature and salinity of oil reservoirs can reduce the viscosity and lead to polymer precipitation. To improve the performance of HPAM in high‐salinity and high‐temperature environments, the responsive amino‐terminated poly(ethylene oxide‐co‐propylene oxide) (PEOPPO) (EO/PO = 19/03) was grafted onto a HPAM backbone. The copolymers were prepared in water using 1‐ethyl‐3‐[3‐(dimethylamino)‐propyl]carbodiimide hydrochloride/N‐hydroxysuccinimide (EDC/NHS) as activators. Structural characterization was performed by1H NMR and Fourier transform infrared (FTIR) and the responsive behavior was investigated by UV–Vis and rheology. Spectroscopic analyses confirmed that copolymers were successfully synthesized. UV–Vis showed that copolymers have combined salt and thermoresponsive character. Rheology in saline medium (ionic strength = 3.75 mol.L−1) revealed that, contrary to unmodified HPAM, HPAM‐g‐PEOPPO have thermothickening behavior and also higher viscosity than HPAM at 70 °C, suggesting the utilization of these copolymers as rheological modifiers under harsh conditions of temperature and salinity, such as the ones found in EOR applications. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2019,136, 47453.
Designing triple‐shape memory polymers from a miscible polymer pair through dual‐electrospinning technique
Authors: Sabzi Mohammad , Ranjbar‐Mohammadi Marziyeh , Zhang Qiwei , Kargozar Saeid , Leng Jinsong , Akhtari Tahereh , Abbasi Robabeh 
Published: January 2019

ABSTRACTRecently, multiple‐shape memory polymers (SMPs) have attracted a great deal of attention in biomedical applications. Therefore, a series of triple‐SMPs were developed by simply blending of two immiscible SMPs exhibiting two distinct transition temperatures, which is required for triple‐shape memory (SM) effect. However, fabrication of triple‐SMPs from completely miscible polymer pairs using the conventional blending approach is a challenging problem. Because this type of blends consists of one homogeneous phase and thereby exhibit only one transition temperature and dual‐SM behavior. To overcome this problem, herein, a novel and versatile strategy is introduced for preparation of phase separated blends from a completely miscible polymer pair, exhibiting triple‐SM behavior. Dual‐electrospinning technique was utilized to simultaneously electrospin poly(lactic acid) (PLA) and poly(vinyl acetate) (PVAc), as a model miscible polymer pair, to obtain an interwoven polymer composite with two well‐separated thermal transitions, as revealed by dynamic mechanical analyze. Consequently, the SM experiments revealed that the electrospun PLA/PVAc composites have triple‐SM behavior. Furthermore, incorporation of graphene nanoplatelets into the composite fibers significantly improved the triple‐SM properties of samples. Additionally, excellent adherence and spreading of the osteoblasts on the fibrous scaffolds containing graphene were observed. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47471.
Centralized sliding mode frequency regulation approach for an uncertain islanded micro grid integrated with disturbance observer
Authors: Deepika Deepika , Kaur Sandeep , Narayan Shiv 
Published: January 2019

AbstractThis paper proposes a novel secondary frequency regulation technique for an uncertain islanded micro grid (MG). The major motivation of the work is to integrate the intrinsic robustness of the sliding mode control scheme with the disturbance observer to estimate and alleviate the unknown mismatched uncertainties caused by renewable resources and load variations. To this end, a dynamical sliding manifold is first utilized and then a control law is derived with Lyapunov's method which stabilizes the MG dynamics. Moreover, in order to ensure faster time domain responses of the closed‐loop system, we employ a power rate reaching law in our proposed control design. Thereafter, the performances of the introduced control strategy are tested on an islanded MG using MATLAB/Simulink, and robustness analysis is also carried out by considering five different case studies. Further, in contrast to the existing approaches such as robust H∞ and robust PID control, the proposed strategy renders appealing time domain characteristics such as settling time, peak overshoot, and integral absolute frequency error.
Prioritizing research for patients requiring surgery in low- and middle-income countries
Authors:   National Institute for Health Research Global Health Research Unit on Global Surgery, Nepogodiev D , Moore R , Biccard B , Rayne S , Costas-Chavarri A , Lapitan M C , Makupe A , Oluseye Adisa A , Uzair Qureshi A , Drake T M , Ademuyiwa A , Alexander P , Allen Ingabire J C , Al-Saqqa S W , Khairy Salem H , Teddy Kojo Anyomih T , Lawani I , Lorena Aguilera M , Ramos-De la Medina A , Spence R , Tabiri S , Yepez R , Smart N , Chu K , Davies J , Fitzgerald J E , Ghosh D , Koto Z , Magill L , Muller E , Ots R , Shaw C , Verjee A , Harrison E M , James Garden O , Sundar S , Glasbey J C , Chakrabortee S , Martin J , Lilford R , Smith M , Brocklehurst P , Morton D G , Bhangu A 
Published: January 2019

Abstract

Background
The National Institute for Health Research Global Health Research Unit on Global Surgery is establishing research Hubs in low- and middle-income countries (LMICs). The aim of this study was for the Hubs to prioritize future research into areas of unmet clinical need for patients in LMICs requiring surgery.

Methods
A modified Delphi process was overseen by the research Hub leads and engaged LMIC clinicians, patients and expert methodologists. A four-stage iterative process was delivered to prioritize research topics. This included anonymous electronic voting, teleconference discussions and a 2-day priority-setting workshop.

Results
In stage 1, Hub leads proposed 32 topics across six domains: access to surgery, cancer, perioperative care, research methods, acute care surgery and communicable disease. In stages 2 and 3, 40 LMICs and 20 high-income countries participated in online voting, leading to identification of three priority research topics: access to surgery; outcomes of cancer surgery; and perioperative care. During stage 4, specific research plans to address each topic were developed by Hub leads at a priority-setting workshop.

Conclusion
This process identified three priority areas for future research relevant to surgery in LMICs. It was driven by front-line LMIC clinicians, patients and other stakeholders representing a diverse range of settings. The results of the prioritization exercise provide a future framework for researchers and funders.
Caesarean section performed by medical doctors and associate clinicians in Sierra Leone
Authors: van Duinen A J , Kamara M M , Hagander L , Ashley T , Koroma A P , Leather A , Elhassein M , Darj E , Salvesen Ø , Wibe A , Bolkan H A 
Published: January 2019

Abstract

Background
Many countries lack sufficient medical doctors to provide safe and affordable surgical and emergency obstetric care. Task-sharing with associate clinicians (ACs) has been suggested to fill this gap. The aim of this study was to assess maternal and neonatal outcomes of caesarean sections performed by ACs and doctors.

Methods
All nine hospitals in Sierra Leone where both ACs and doctors performed caesarean sections were included in this prospective observational multicentre non-inferiority study. Patients undergoing caesarean section were followed for 30 days. The primary outcome was maternal mortality, and secondary outcomes were perinatal events and maternal morbidity.

Results
Between October 2016 and May 2017, 1282 patients were enrolled in the study. In total, 1161 patients (90·6 per cent) were followed up with a home visit at 30 days. Data for 1274 caesarean sections were analysed, 443 performed by ACs and 831 by doctors. Twin pregnancies were more frequently treated by ACs, whereas doctors performed a higher proportion of operations outside office hours. There was one maternal death in the AC group and 15 in the doctor group (crude odds ratio (OR) 0·12, 90 per cent confidence interval 0·01 to 0·67). There were fewer stillbirths in the AC group (OR 0·74, 0·56 to 0·98), but patients were readmitted twice as often (OR 2·17, 1·08 to 4·42).

Conclusion
Caesarean sections performed by ACs are not inferior to those undertaken by doctors. Task-sharing can be a safe strategy to improve access to emergency surgical care in areas where there is a shortage of doctors.