bluuebunny/crossref_metadata_2025_split huggingface dataset:
Muslim customer’s shopping experiences in multicultural retail environment
Authors: Ihtiyar Ali 
Published: February 2019

PurposeThis study aims to understand better the impact of intercultural communication, social environment and personality on customer satisfaction and post-purchase stage in retailing from Muslim customers’ perspective. In this endeavour, this study illustrates the unique context of intercultural communication to highlight several improvements contributing towards the advancement of intercultural communication literature.Design/methodology/approachThis research adopted a survey approach where 450 questionnaires were obtained among selected grocery retailers in Klang Valley, Malaysia. The measurement of the constructs and their interrelationships were examined based on partial least squares structural equation modelling (PLS-SEM).FindingsThe findings partially validated the proposed framework with statistically significant relationships among all constructs. Furthermore, it exposed additional insights into some practical and conceptual solutions for addressing intercultural communication of religiously and culturally diverse service encounters in the Malaysian grocery retail industry. These contributions postulated an impetus for future research in various service settings.Originality/valueBased on the theories, this study assessed the role of the social environment and personality of grocery retail customers on intercultural communication competence (ICC). It also examined the impacts of ICC on inter-role congruence and interaction comfort. It is anticipated that by filling this knowledge gap, the research assisted in strengthening retail communication strategies, which require intercultural communication adjustments in a multicultural business environment. ICC is expected to improve the retail industry’s competitiveness when it positively influences inter-role congruence and interaction comfort among customers.
Investigation of anti‐inflammatory, nitric oxide donating, vasorelaxation and ulcerogenic activities of 1, 3‐diphenylprop‐2‐en‐1‐one derivatives in animal models
Authors: Sherikar Amol , Dhavale Rakesh , Bhatia Manish 
Published: February 2019

SummaryThe main aim of this work is to find out novel chemical moieties with potent anti‐inflammatory and vasorelaxant activities with reduced gastric toxicities. For fulfilling the above aim, here we investigated novel chalcones (1, 3‐diphenylprop‐2‐en‐1‐one derivatives) with nitric oxide (NO) and hydrogen sulphide (H2S) donating potency for anti‐inflammatory activity by carrageenan‐induced rat paw oedema. These molecules then further evaluated for in‐vitro NO‐releasing potency and vasorelaxation effect on isolated adult goat aortic tissue. The promising molecules were further screened for ulcerogenic activity in the rat model. The tested compounds produced % inhibition in paw oedema ranging from 29.16% to 79.69% and standard drug Diclofenac sodium produced 85.30% reduction in paw oedema after 5 hours. Out of this dataset, compounds AI1, AI7, Ca1, B2, B10, D2, and E8 showed 73.01%, 79.69%, 75.02%, 75.46%, 74.35%, 73.9% and 74.35% reduction in paw oedema respectively, which is approximately 80%–90% to that of standard Diclofenac sodium. The compound Ca1 was found to release 0.870 ± 0.025 mol/mol of NO and standard Glyceryl trinitrate (GTN) was found to release 0.983 ± 0.063 mol/mol of NO. The compound Ca1 produced 950.2 μmol/L of EC50 whereas standard GTN produced 975.8 μmol/L of EC50 for aortic smooth relaxation. The compounds Ca1 produced 0.1117 of ulcer index which is far less than that of standard Diclofenac sodium (1.148). The potent lead molecules were further evaluated to understand the mechanism of vasorelaxation by using specific antagonists or blockers of NO and H2S.
From ‘holding pen’ to ‘a space to breathe’: affective landscapes in a newly‐integrated sexual health clinic
Authors: Wright Sarah 
Published: February 2019

AbstractThis paper examines the role of affective landscapes in the formation of attendees’ experiences at a re‐provisioned, integrated sexual and reproductive healthcare facility. The ‘One‐Stop Shop’ (OSS) is an example of the organisational shift towards integrated services occurring across the UK, bringing together in one clinic the historically discreet services of genitourinary medicine, HIV medicine and Family Planning. An ethnographically‐informed study of new spaces of care and changed organisation, this paper focuses on the experiences of 29 attendees as they made their way along the clinic's care pathways. Drawing on concepts of affect and atmosphere to augment the analytic lens of ‘therapeutic landscapes’, this paper demonstrates how various spaces of the clinic influenced attendees’ experiences. A cramped, featureless ‘holding pen’, the foyer served to exacerbate pre‐existing anxieties while creating new fears. The main waiting room, an organisational sorting space, both soothed and aggravated attendees’ concerns. Serving as an architectural feature to connect the old Victorian hospital with the new clinical extension, the atrium was experienced as a space to breathe, with an affective atmosphere that challenged the assumed unpleasantness of sexual health clinics. This paper demonstrates how affective landscapes of the clinic shape attendee experiences in a novel setting.
Effectiveness of dietetic consultation for lowering blood lipid levels in the management of cardiovascular disease risk: A systematic review and meta‐analysis of randomised controlled trials
Authors: Ross Lynda J. , Barnes Katelyn A. , Ball Lauren E. , Mitchell Lana J. , Sladdin Ishtar , Lee Patricia , Williams Lauren T. 
Published: February 2019

AimEvidence of the effectiveness of dietetic consultation for the management of cardiovascular disease (CVD) risk factors has not been previously synthesised. A systematic review and four meta‐analyses evaluated the effectiveness of dietetic consultation for lowering blood lipid levels in high‐risk individuals in primary health‐care settings.MethodsOf the 4860 records identified, 10 eligible randomised controlled trials (RCTs, n = 1530) were evaluated for reporting blood lipid outcomes following dietetic consultation (DN)—defined as at least one exclusive individual face‐to‐face consultation with a dietitian and comparators (C)—defined as no nutrition intervention or usual or minimal care provided by physicians and/or nurses.ResultsDN groups were effective for lowering blood lipid levels across nine studies reporting total cholesterol (TC) and LDL; and across five of six studies reporting triglycerides (TG). Between‐group differences were not consistently assessed, with significance levels reported in four studies all in favour of DN, P < 0.05. Meta‐analyses for TC and LDL (seven studies) confirmed DN and C groups were equally effective, P > 0.05; and for TG (six studies) DN groups were significantly more effective than C groups, P < 0.05).ConclusionsThis review provides RCT evidence that dietetic counselling is effective for lowering TG levels and at least as effective as usual and minimal care for improving cholesterol levels in high‐risk individuals in primary health care. However, more adequate reporting of methods and greater consistency in timing interventions and data collection will enhance the quality of the evidence and increase confidence in the health benefits of dietetic counselling for the management of CVD risk.
The Role of Solid Support Bound Metal Chelators on System‐Dependent Synergy and Antagonism with Nisin
Authors: Herskovitz Joshua E. , Worobo Randy W. , Goddard Julie M. 
Published: February 2019

AbstractActive packaging can enhance the performance of natural antimicrobials in controlling food spoilage and waste, while addressing consumer demands for cleaner labels. Yet, synergies are system dependent, with some conditions counterintuitively promoting antagonistic effects. In particular, metal chelators can improve performance of certain natural antimicrobials and have been incorporated in nonmigratory metal chelating active packaging technologies. However, the influence of chelating ligand chemistry on antimicrobial efficacy has not been investigated in microbial spoilage models. The effect of three commercial chelating resins on the growth of Alicyclobacillus acidoterrestris ATCC 49025, a thermoduric acidophilic spore‐former, in growth media and apple juice was investigated. Dowex MAC‐3, Chelex 100, and Lewatit TP260 were used as models for metal chelating active packaging containing carboxylic acid (CA), iminodiacetic acid (IDA), and aminomethylphosphonic acid (AMPA) ligands. Diameters (CA = 472.4 ± 117.2 μm, IDA = 132.93 ± 26.71 μm, and AMPA = 498.3 ± 29.24 μm), dissociation kinetics (CA = 6.44 ± 0.109, IDA = ‐0.977 ± 9.94, AMPA = 7.43 ± 0.193), and metal chelating capacities (CA = 1.16 × 10−4 mol/g, IDA = 1.52 × 10−3 mol/g, and AMPA = 4.67 × 10−4 mol/g) were used to distinguish differences in antimicrobial efficacies. Growth of A. acidoterrestris in acidified Potato Dextrose Broth over 24 hr with chelating resins indicated early death phase for CA and IDA resins and bactericidal for AMPA resin. However, viability in commercial apple juice with the inclusion of nisin and chelating resins was variable, with IDA resin significantly (P < 0.05) increasing viability while the effect of CA and AMPA resins remained elusive. This work emphasizes the importance of biological repeatability and correct statistical modeling in identifying conditions under which the antimicrobial intervention of nisin in real food systems, such as acidic beverages and juices, are synergistic or antagonistic.Practical ApplicationNew technologies to control microbial food spoilage and waste need to be explored to address consumers on‐going demands for reducing additive use. Solid support bound metal chelators can both promote and control microbial growth when used in conjunction with nisin, a natural antimicrobial. This work explores how system conditions can render a given technology either synergistic or antagonistic, and highlights the importance of sufficient biological replicates in experimental design.
Chronic Oral Administration of Tenebrio molitor Extract Exhibits Inhibitory Effect on Glucocorticoid Receptor Overexpression in the Hippocampus of Ovariectomy‐Induced Estrogen Deficient Mice
Authors: Kim Gwang‐Ho , Baek Hye Kyung , Lee Jong Suk , Kim Sung‐Jo , Yi Sun Shin 
Published: February 2019

AbstractIt has been reported that estrogen deficiency in female disrupts systemic endocrinologic regulatory mechanisms, finally leading to osteoporotic condition. Estrogen deficiency also down‐regulates brain functions due to its deficits of its original roles in a number of neurological events. Therefore, it is necessary to find alternative materials that can prevent osteoporotic condition and maintain normal brain functions to correct such hormone deficiency. In the present study, we found that novel compounds originated from larvae of Tenebrio molitor (TM) possessed anti‐osteoporotic effect. They could also prevent abnormal progressive brain function by deaccelerating enhanced HPA‐axis negative feedback while maintaining neurogenesis in hippocampus. We daily administered TM to ovariectomized (OVX) ddY mice for 4 weeks and then performed histological and hormonal evaluations for its anti‐osteoporotic effects. In addition, we investigated glucocorticoid receptor (GR) expression and neuroblast expression (DCX) in the hippocampal dentate gyrus morphologically by immunohistochemistry analysis. According to our results, TM has anti‐osteoporotic effects. It also tends to bring interfered brain environment back to normal condition.These results suggest that TM might have anti‐osteoporosis effect and enhancing effects on enrichment of environment in brain by being antidestroyed hormonal deficiency simultaneously. This is the first study to report that TM can be used as source of bioactive substance to prevent decreased neurogenesis and impaired HPA axis driven by high GR expression in the hippocampus in hormonal deficient female animals.Practical ApplicationAnti‐osteoporosis effect and stress resistance due to improved brain function caused by the ingestion of Tenebrio molitor extract were observed in postmenopausal women. T. molitor is available as a nutritional supplement for bone and brain health, which menopausal women need most.
Value of contrast‐enhanced harmonic endoscopic ultrasonography in differentiating between gastrointestinal stromal tumors: A meta‐analysis
Authors: Tang Jia Yue , Tao Ke Gong , Zhang Li Yuan , Wu Kai Ming , Shi Jian , Zeng Xin , Lin Yong 
Published: February 2019

ObjectiveContrast‐enhanced harmonic endoscopic ultrasonography (CH‐EUS) is a valuable device to diagnose and determine the malignant potential of gastrointestinal stromal tumors (GIST) as early as possible when making clinical therapeutic decisions. This study aimed to estimate the ability of CH‐EUS to discriminate between GIST and benign submucosal lesions (SML) and to predict their malignant potential.MethodsPubMed, MEDLINE, EMBASE, the Web of Science, and Cochrane Central Register of Controlled Trials databases were screened. Using the data provided in the literatures, 2 × 2 tables were constructed to obtain the pooled sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio. A receiver operating characteristic (ROC) curve was generated and the area under the ROC curve (AUROC) was calculated.ResultsFour studies with a total of 187 patients were identified to evaluate the value of CH‐EUS in discriminating between GIST and benign SML. The pooled sensitivity, specificity, and AUROC were 89% (95% CI 0.82‐0.93), 82% (95% CI 0.66‐0.92), and 0.89, respectively. Five studies including 143 patients were analyzed to assess the accuracy of CH‐EUS in determining the malignant potential of GIST. The pooled sensitivity, specificity, and AUROC curve of CH‐EUS were 96% (95% CI 0.90‐0.99), 53% (95% CI 0.40‐0.66), and 0.92, respectively.ConclusionsCH‐EUS is a safe, noninvasive method that can distinguish between GIST and benign subepithelial lesions and to predict their malignant potential to a certain extent. Large‐scale, multicenter prospective studies are needed in the future.
Quantitative immunochemical fecal occult blood test for neoplasia in colon cancer screening
Authors: Yuan Si Yi , Wu Wei , Fu Jing , Lang Yi Xuan , Li Ji Chi , Guo Ye , Wang Ya Nan , Qian Jia Ming , Li Jing Nan 
Published: February 2019

OBJECTIVETo investigate the performance of the quantitative immunochemical fecal occult blood test (qFIT) and to determine the association between the fecal hemoglobin (Hb) level and the location and size of adenomas and the stages of colorectal cancer (CRC).METHODSA total of 692 participants were included in the study. Their fecal Hb level was measured using an OC‐SENSA MICRO qFIT. The colonoscopy results, including the location, size, and histological features of the adenomas, as well as the relationship between the Hb level and different characteristics were analyzed. Performance of the qFIT at various thresholds of fecal Hb levels was evaluated.RESULTSAdvanced colorectal neoplasia (ACRN) was identified in 76 patients based on the colonoscopic and pathological examinations. Large adenomas (≥10 mm) had a higher fecal Hb level than small adenomas (<10 mm). Advanced adenomas located on the left side of the colon presented with a higher fecal Hb level than those on the right side (P = 0.022). Stage III‐IV CRC patients had a significantly higher Hb level than stage I‐II patients (P = 0.013). The sensitivity and specificity of qFIT for ACRN was 51.3% and 86.4%，respectively, with the best cut‐off level of 400 ng/mL. The sensitivity and specificity for CRC was 61.0% and 89.1%, with the best cut‐off level of 500 ng/mL.CONCLUSIONSqFIT has an acceptable sensitivity and specificity for ACRN detection. Furthermore, the qFIT results are associated with the location and size of adenomas as well as the grade of CRC.
The recent past and promising future for data integration methods to estimate species’ distributions
Authors: Miller David A. W. , Pacifici Krishna , Sanderlin Jamie S. , Reich Brian J. 
Published: February 2019

AbstractWith the advance of methods for estimating species distribution models has come an interest in how to best combine datasets to improve estimates of species distributions. This has spurred the development of data integration methods that simultaneously harness information from multiple datasets while dealing with the specific strengths and weaknesses of each dataset.We outline the general principles that have guided data integration methods and review recent developments in the field. We then outline key areas that allow for a more general framework for integrating data and provide suggestions for improving sampling design and validation for integrated models.Key to recent advances has been using point‐process thinking to combine estimators developed for different data types. Extending this framework to new data types will further improve our inferences, as well as relaxing assumptions about how parameters are jointly estimated. These along with the better use of information regarding sampling effort and spatial autocorrelation will further improve our inferences.Recent developments form a strong foundation for implementation of data integration models. Wider adoption can improve our inferences about species distributions and the dynamic processes that lead to distributional shifts.
Differential gene expression and stereological analyses of the cerebellum following methamphetamine exposure
Authors: Eskandarian Boroujeni Mahdi , Peirouvi Tahmineh , Shaerzadeh Fatemeh , Ahmadiani Abolhasan , Abdollahifar Mohammad Amin , Aliaghaei Abbas 
Published: February 2019

AbstractMethamphetamine (METH) is a highly addictive psychostimulant that profoundly aimed at monoaminergic systems in the brain. Despite the leading role of cerebellum in sensorimotor control as well as augmented locomotor activity under the influence of METH, there are few studies examining the effect of METH administration on gene expression profiling and structural consequences in the cerebellar region. Thus, we sought to explore the effects of METH on the cerebellum, from gene expression changes to structural alterations. In this respect, we investigated genome‐wide mRNA expression using high throughput RNA‐seq technology and confirmatory quantitative real‐time PCR, accompanied by stereological analysis of cerebellar layers along with identification of reactive astrogliosis by glial fibrillary acidic protein and behavioral assessment following METH exposure. According to our RNA‐seq data, 473 unique differentially expressed genes (DEG) were detected upon METH injections in which a large number of these genes engage basically in biological regulations and metabolic processes, chiefly located in nucleus and membrane. In addition, pathway analysis of METH‐induced DEG revealed several enriched signaling cascades related largely to immune response, neurotransmission, cell growth, and death. Further, METH induced a significant reduction in volumes of cerebellar layers (molecular, granular, and Purkinje) and a decrease in the white matter volume along with a rise in astrogliosis as well as increased locomotor activity. In conclusion, considering gene expression changes combined with structural alterations of the cerebellum in response to METH, these data suggest METH‐induced neurotoxicity in the cerebellar region.
Grass greenness and grass height promote the resource partitioning among reintroduced Burchell's zebra and blue wildebeest in southern Mozambique
Authors: Mandlate Luís Comissário , Arsenault Randal , Rodrigues Flávio H. G. 
Published: February 2019

AbstractDifferences in the selection of habitat and specific dietary items support resource partitioning and coexistence of sympatric African grazing herbivores, such as zebra and wildebeest. In Maputo Special Reserve (MSR), southern Mozambique, these two species were extirpated during the civil war (1977–1992); since 2010, they have been reintroduced into the Reserve. Identifying the resource selection by reintroduced species and how these species coexist, while utilising the same resources, is both of ecological interest and important for the management of wildlife communities and parks. This is a key application of our research. Therefore, the present study investigated resource partitioning between Burchell's zebra (Equus burchelli, Smuts 1832) and blue wildebeest (Connochaetes taurinus, Burchell 1823) in the MSR. We conducted the study from July 2016 to June 2017. The data were collected by direct observation, driving the vehicle along the reserve's roads that covered the vegetation communities where zebras and wildebeest are known to commonly occur. The composition of the diet and specific features of the grass grazed by the two species, including greenness, height, and the number of stems, were assessed. The widely available grass, Aristida barbicollis, contributed most to the diet of both herbivores. The dietary overlap between the two herbivores was higher during the dry season (95%) than wet season (86%). Resources partitioning appears to be determined, principally, by the height and greenness of the grass, with the zebra grazing taller grass, which may facilitate the access of the wildebeest to the greener, lower proportion of the forage. That results follow the expectation that, among native herbivores, overlap in resource use is not expected based on evolutionary segregation.
Oncologists' and pediatric oncologists' perspectives and challenges for fertility preservation
Authors: Lampic Claudia , Wettergren Lena 
Published: February 2019

AbstractInternational guidelines recommend that health‐care providers initiate discussions about the impact of treatment on fertility with cancer patients of reproductive age, or with parents/legal guardians of children, as early as possible in the treatment process. Still, both physicians and patients confirm that this is not always the case. This literature review summarizes findings regarding oncologists' and pediatric oncologists' perspectives and challenges of providing fertility preservation care, and points out directions for development. The results concerning the challenges facing clinicians are consistent and encompass both internal and external factors. The internal factors relate to clinicians' characteristics and values and include their knowledge of fertility preservation, clinical experience, perceptions of patients' plans for children, and how comfortable they are to discuss sensitive issues. The external factors relate to the availability of health‐care services and the organization of care, including the clinicians' working conditions. Several strategies to overcome identified challenges for clinicians to provide high‐quality fertility preservation care are proposed. These include educational interventions to increase clinicians' knowledge about treatment‐induced fertility impairment and available fertility preservation measures, as well as interventions aimed to increase clinicians' readiness and competence to communicate with patients and their parents. In addition, different types of educational resources for patients have been suggested to improve patient‐provider communication about fertility preservation, such as age‐appropriate brochures and decision aids. Organizational approaches suggested to address the identified external factors include development and implementation of policies and guidelines as well as closer collaboration between oncological and fertility clinics. Also, modifications of electronic medical record systems may support clinicians by prompting the documentation of discussions about potential treatment impact on future fertility and about available fertility preservation options. The development and implementation of multifaceted oncofertility programs appears to be a promising way forward towards high‐quality fertility preservation care meeting patients' needs.