bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of causal models and beliefs in interpreting health claims
Authors: Banks Adrian P. , Egan Bernadette , Hodgkins Charo E. , Peacock Matthew , Raats Monique M. 
Published: July 2018

ObjectiveHealth claims on food packaging are regulated to inform and protect consumers; however, many consumers do not accurately interpret the meaning of the claims. Whilst research has shown different types of misinterpretation, it is not clear how those interpretations are formed. The aim of this study was to elicit the causal beliefs and causal models about food and health held by consumers, that is their understanding of the causal relationships between nutrients, health outcomes, and the causal pathways connecting them, and investigate how well this knowledge explains the variation in inferences they draw about health benefits from health claims.MethodA total of 400 participants from Germany, the Netherlands, Spain, Slovenia, and the United Kingdom were presented with seven authorized health claims and drew inferences about the health benefits of consuming nutrients specified in the claim. Then, their personal causal models of health were elicited along with their belief in the truth and familiarity with the claims.ResultsThe strength of inferences about health benefits that participants drew from the claims was predicted independently by the strength of the relevant causal pathways within the causal model, and belief in the truth of the claim, but not familiarity with the claim. Participants drew inferences about overall health benefits of the nutrients by extrapolating from their causal models of health.ConclusionConsumers’ interpretation of claims is associated with their belief in the claim and their causal models of health. This prior knowledge is used to interpret the claim and draw inferences about overall health benefits that go beyond the information in the claim. Therefore, efforts to improve consumers’ understanding and interpretation of health claims must address both their wider causal models of health and their knowledge of specific claims.
Statement of Contribution

What is already known on this subject?

Health claims influence the likelihood of buying a product.

But consumers do not accurately understand or interpret health claims.

What does this study add?

Consumers’ interpretation of health claims is mediated by their personal causal model of health.

Consumers draw inferences that go beyond what is claimed by extrapolating from their personal causal model of health.

Consumers are also influenced directly by their belief in the claim, but not frequency of exposure to it.
The other facets of family life and their role in the evolution of animal sociality
Authors: Kramer Jos , Meunier Joël 
Published: July 2018

ABSTRACTFamily life forms an integral part of the life history of species across the animal kingdom and plays a crucial role in the evolution of animal sociality. Our current understanding of family life, however, is almost exclusively based on studies that (i) focus on parental care and associated family interactions (such as those arising from sibling rivalry and parent‐offspring conflict), and (ii) investigate these phenomena in the advanced family systems of mammals, birds, and eusocial insects. Here, we argue that these historical biases have fostered the neglect of key processes shaping social life in ancestral family systems, and thus profoundly hamper our understanding of the (early) evolution of family life. Based on a comprehensive survey of the literature, we first illustrate that the strong focus on parental care in advanced social systems has deflected scrutiny of other important social processes such as sibling cooperation, parent–offspring competition and offspring assistance. We then show that accounting for these neglected processes – and their changing role over time – could profoundly alter our understanding of the origin and subsequent evolution of family life. Finally, we outline how this ‘diachronic’ perspective on the evolution of family living provides novel insights into general processes driving the evolution of animal sociality. Overall, we infer that the explicit consideration of thus‐far neglected facets of family life, together with their study across the whole diversity of family systems, are crucial to advance our understanding of the processes that shape the evolution of social life.
Aberrant methylation and silencing of the SPINT2 gene in high‐grade gliomas
Authors: Fukushima Tsuyoshi , Kawaguchi Makiko , Yamamoto Koji , Yamashita Fumiki , Izumi Aya , Kaieda Takashi , Takezaki Yuka , Itoh Hiroshi , Takeshima Hideo , Kataoka Hiroaki 
Published: July 2018

Hepatocyte growth factor activator inhibitor type 2 (HAI‐2), encoded by the SPINT2 gene, is a membrane‐anchored protein that inhibits proteases involved in the activation of hepatocyte growth factor (HGF), a ligand of MET receptor. Epigenetic silencing of the SPINT2 gene has been reported in a human glioblastoma cell line (U87) and glioblastoma‐derived cancer stem cells. However, the incidence of SPINT2 methylation in tumor tissues obtained from glioma patients is unknown. In this study, we analyzed the methylation status of the SPINT2 gene of eight human glioblastoma cell lines and surgically resected glioma tissues of different grades (II, III, and IV) by bisulfite sequence analysis and methylation‐specific PCR. Most glioblastoma lines (7/8) showed methylation of the SPINT2 gene with a significantly reduced level of SPINT2mRNA compared to cultured astrocytes and normal brain tissues. However, all glioblastoma lines expressed mRNA for HGF activator (HGFAC), a target protease of HAI‐2/SPINT2. Forced expression of SPINT2 reduced MET phosphorylation of U87 glioblastoma cells both in vitro and in intracranial xenografts in nude mice. Methylation‐specific PCR analysis of the resected glioma tissues indicated notable methylation of the SPINT2 gene in 33.3% (2/6), 71.4% (10/14), and 74.3% (26/35) of grade II, III, and IV gliomas, respectively. Analysis of RNA sequencing data in a public database indicated an increased HGFAC/SPINT2 expression ratio in high‐grade compared to low‐grade gliomas (P = .01). In summary, aberrant methylation of the SPINT2 gene is frequently observed in high‐grade gliomas and might confer MET signaling in the glioma cells.
Bringing the Real World Into Developmental Science: A Commentary on Weber, Fernald, and Diop (2017)
Authors: Morelli Gilda , Bard Kim , Chaudhary Nandita , Gottlieb Alma , Keller Heidi , Murray Marjorie , Quinn Naomi , Rosabal‐Coto Mariano , Scheidecker Gabriel , Takada Akira , Vicedo Marga 
Published: July 2018

This article examines the parent intervention program evaluated by Weber et al. (2017) and argues that there are scientific and ethical problems with such intervention efforts in applied developmental science. Scientifically, these programs rely on data from a small and narrow sample of the world's population; assume the existence of fixed developmental pathways; and pit scientific knowledge against indigenous knowledge. The authors question the critical role of talk as solely providing the rich cognitive stimulation important to school success, and the critical role of primary caregivers as teachers of children's verbal competency. Ethically, these programs do not sufficiently explore how an intervention in one aspect of child care will affect the community's culturally organized patterns of child care.
Interactive Visual Exploration of Local Patterns in Large Scatterplot Spaces
Authors: Chegini Mohammad , Shao Lin , Gregor Robert , Lehmann Dirk J. , Andrews Keith , Schreck Tobias 
Published: July 2018

AbstractAnalysts often use visualisation techniques like a scatterplot matrix (SPLOM) to explore multivariate datasets. The scatterplots of a SPLOM can help to identify and compare two‐dimensional global patterns. However, local patterns which might only exist within subsets of records are typically much harder to identify and may go unnoticed among larger sets of plots in a SPLOM. This paper explores the notion of local patterns and presents a novel approach to visually select, search for, and compare local patterns in a multivariate dataset. Model‐based and shape‐based pattern descriptors are used to automatically compare local regions in scatterplots to assist in the discovery of similar local patterns. Mechanisms are provided to assess the level of similarity between local patterns and to rank similar patterns effectively. Moreover, a relevance feedback module is used to suggest potentially relevant local patterns to the user. The approach has been implemented in an interactive tool and demonstrated with two real‐world datasets and use cases. It supports the discovery of potentially useful information such as clusters, functional dependencies between variables, and statistical relationships in subsets of data records and dimensions.
Fast and Accurate CNN‐based Brushing in Scatterplots
Authors: Fan Chaoran , Hauser Helwig 
Published: July 2018

AbstractBrushing plays a central role in most modern visual analytics solutions and effective and efficient techniques for data selection are key to establishing a successful human‐computer dialogue. With this paper, we address the need for brushing techniques that are bothfast, enabling a fluid interaction in visual data exploration and analysis, and alsoaccurate, i.e., enabling the user to effectively select specific data subsets, even when their geometric delimination is non‐trivial. We present a new solution for a near‐perfect sketch‐based brushing technique, where we exploit a convolutional neural network (CNN) for estimating the intended data selection from a fast and simple click‐and‐drag interaction and from the data distribution in the visualization. Our key contributions include a drastically reduced error rate—now below 3%, i.e., less than half of the so far best accuracy—and an extension to a larger variety of selected data subsets, going beyond previous limitations due to linear estimation models.
Assessing Effects of Task and Data Distribution on the Effectiveness of Visual Encodings
Authors: Kim Younghoon , Heer Jeffrey 
Published: July 2018

AbstractIn addition to the choice of visual encodings, the effectiveness of a data visualization may vary with the analytical task being performed and the distribution of data values. To better assess these effects and create refined rankings of visual encodings, we conduct an experiment measuring subject performance across task types (e.g., comparing individual versus aggregate values) and data distributions (e.g., with varied cardinalities and entropies). We compare performance across 12 encoding specifications of trivariate data involving 1 categorical and 2 quantitative fields, including the use of x, y, color, size, and spatial subdivision (i.e., faceting). Our results extend existing models of encoding effectiveness and suggest improved approaches for automated design. For example, we find that colored scatterplots (with positionally‐coded quantities and color‐coded categories) perform well for comparing individual points, but perform poorly for summary tasks as the number of categories increases.
PixelSNE: Pixel‐Aligned Stochastic Neighbor Embedding for Efficient 2D Visualization with Screen‐Resolution Precision
Authors: Kim Minjeong , Choi Minsuk , Lee Sunwoong , Tang Jian , Park Haesun , Choo Jaegul 
Published: July 2018

AbstractEmbedding and visualizing large‐scale high‐dimensional data in a two‐dimensional space is an important problem, because such visualization can reveal deep insights of complex data. However, most of the existing embedding approaches run on an excessively high precision, even when users want to obtain a brief insight from a visualization of large‐scale datasets, ignoring the fact that in the end, the outputs are embedded onto a fixed‐range pixel‐based screen space. Motivated by this observation and directly considering the properties of screen space in an embedding algorithm, we propose Pixel‐Aligned Stochastic Neighbor Embedding (PixelSNE), a highly efficient screen resolution‐driven 2D embedding method which accelerates Barnes‐Hut tree‐based t‐distributed stochastic neighbor embedding (BH‐SNE), which is known to be a state‐of‐the‐art 2D embedding method. Our experimental results show a significantly faster running time for PixelSNE compared to BH‐SNE for various datasets while maintaining comparable embedding quality.
Visual Analysis of protein‐ligand interactions
Authors: Vázquez P. , Hermosilla P. , Guallar V. , Estrada J. , Vinacua A. 
Published: July 2018

AbstractThe analysis of protein‐ligand interactions is complex because of the many factors at play. Most current methods for visual analysis provide this information in the form of simple 2D plots, which, besides being quite space hungry, often encode a low number of different properties. In this paper we present a system for compact 2D visualization of molecular simulations. It purposely omits most spatial information and presents physical information associated to single molecular components and their pairwise interactions through a set of 2D InfoVis tools with coordinated views, suitable interaction, and focus+context techniques to analyze large amounts of data. The system provides a wide range of motifs for elements such as protein secondary structures or hydrogen bond networks, and a set of tools for their interactive inspection, both for a single simulation and for comparing two different simulations. As a result, the analysis of protein‐ligand interactions of Molecular Simulation trajectories is greatly facilitated.
Information Visualization Evaluation Using Crowdsourcing
Authors: Borgo R. , Micallef L. , Bach B. , McGee F. , Lee B. 
Published: July 2018

AbstractVisualization researchers have been increasingly leveraging crowdsourcing approaches to overcome a number of limitations of controlled laboratory experiments, including small participant sample sizes and narrow demographic backgrounds of study participants. However, as a community, we have little understanding on when, where, and how researchers use crowdsourcing approaches for visualization research. In this paper, we review the use of crowdsourcing for evaluation in visualization research. We analyzed 190 crowdsourcing experiments, reported in 82 papers that were published in major visualization conferences and journals between 2006 and 2017. We tagged each experiment along 36 dimensions that we identified for crowdsourcing experiments. We grouped our dimensions into six important aspects: study design & procedure, task type, participants, measures & metrics, quality assurance, and reproducibility. We report on the main findings of our review and discuss challenges and opportunities for improvements in conducting crowdsourcing studies for visualization research.
Effectiveness of submandibular duct relocation in 91 children with excessive drooling: A prospective cohort study
Authors: Kok Saskia E. , Erasmus Corrie E. , Scheffer Arthur R. T. , van Hulst Karen , Rovers Maroeska M. , van den Hoogen Frank J. A. 
Published: July 2018

ObjectiveTo evaluate the effectiveness of submandibular duct relocation (SMDR) in drooling children with neurological disorders.DesignProspective cohort study.SettingAcademic Outpatient Saliva Control Clinic.ParticipantsNinety‐one children suffering from moderate to severe drooling.Main outcome measuresDirect observational drooling quotient (DQ; 0‐100) and caretaker Visual Analogue Scale (VAS; 0‐100). Secondary outcome measures were drooling severity (DS) and frequency rating scales.ResultsThe DQ at baseline, 8 and 32 weeks postoperatively was 26.4, 12.3 and 10.8, respectively. VAS score decreased from 80.1 at baseline to 28.3 and 37.0 at 8 and 32 weeks after surgery. Median DS at baseline, 8 and 32 weeks was 5, 3 and 4, whereas the drooling frequency median scores were 4, 2 and 2, respectively. Five children required prolonged intubation due to transient floor of the mouth swelling, two of whom developed a ventilator‐associated pneumonia. Another child developed atelectasis with postoperative pneumonia. Two more children needed tube feeding because of postoperative eating difficulties for 3 days or suprapubic catheterisation for urinary retention. Children aged 12 years or older (OR = 3.41; P = 0.03) and those with adequate stability and position of the head (OR = 2.84; P = 0.09) appeared to benefit most from treatment.ConclusionsSubmandibular duct relocation combined with excision of the sublingual glands appears to be relatively safe and effective in diminishing visible drooling in children with neurological disorders, particularly in children aged 12 years and older and those without a forward head posture.
Systemic therapies for leg ulcers
Authors: Dissemond Joachim , Erfurt‐Berge Cornelia , Goerge Tobias , Kröger Knut , Funke‐Lorenz Carolin , Reich‐Schupke Stefanie 
Published: July 2018

SummarySuccessful management of patients with leg ulcers requires identification of the underlying etiology, with subsequent initiation of causal treatment, if feasible. Supplementary measures of first choice include stage‐adjusted wound treatment, usually combined with compression therapy. The significance of systemic drugs has been the subject of controversial debate, depending on the underlying cause of the condition. The present review article is therefore meant to highlight current aspects of systemic drug therapies for the treatment of leg ulcers associated with chronic venous insufficiency, peripheral arterial disease, livedoid vasculopathy, vasculitis, necrobiosis lipoidica, calciphylaxis and pyoderma gangrenosum.In summary, the majority of therapeutic options presented herein are used off‐label. While systemic drugs are promising options for the more common types of wounds such as venous, mixed or arterial leg ulcers, they do not represent the current standard of treatment. By contrast, systemic agents play a key role in the management of many of the other disorders presented herein. These agents primarily include immunomodulatory and rheological drugs used to expedite wound healing.
Employer‐provided training, innovation and skills in post‐Soviet countries
Authors: Kupets Olga 
Published: July 2018

AbstractThis paper analyzes the extent of employer‐provided training in Armenia, Azerbaijan, Georgia and Ukraine and investigates its relationship with innovation, having international business contacts, use of computers at work, reported skills shortages and other firm characteristics. It contributes to the literature by examining different types of training – initial on‐the‐job learning, more formal in‐house training and external training, which is provided by firms to two categories of workers – white‐ and blue‐collar workers. After controlling for a range of firm characteristics, we find a positive link between technological innovation and intensity of training of all types provided to white‐collar workers that points to the technology‐skills complementarity. Furthermore, the level of computer use at work is a significant determinant of the incidence and intensity of external training provided to white‐collar and blue‐collar workers.
Pentecostalism, Female Spirit‐Filled Politicians, and Populism in Zambia
Authors: Kaunda Mutale M. , Kaunda Chammah J. 
Published: July 2018

AbstractThis article postulates that the way African Pentecostal women politicians utilize the religious discourse of wifely submission in exercising religio‐political power reinforces populism and perpetuates patriarchy‐informed politics in Zambia. It will demonstrate that their religio‐political engagement is based on ideological allegiance to institutional political systems of power tailored to promote the patriarchal agenda.
Inquiry of Pentecostalism Regarding Pneumatology: A Theological Suggestion of a Feminist Perspective
Authors: Chung Meehyun 
Published: July 2018

AbstractThis article revisits the legacy of the Pentecostal movement in Korea based on pneumatology and reflects on the issues of Pentecostalism from a feminist perspective. It elaborates on (1) the patriarchal top‐down hierarchy by personal cult, (2) gender injustice, and (3) the dualistic conflict of ideology. Pentecostalism is an important trend in World Christianity and in the Korean landscape of Christianity in particular. In terms of impact on society, Pentecostalism is more influential compared to Minjung theology, and these two streams have common interest regarding marginalized people. Given global challenges and growing economic disparity, it is also relevant to promote cooperation between the evangelical and ecumenical movements. To promote a new paradigm of mission and evangelism in the 21st century in the Korean context, we need to improve several aspects thereof in terms of justice, peace, and integration of creation. In this era of liberal market capitalism, when human individualization and economic inequality are accelerating, what we need is a purpose for common goodness that is based on the incarnation of God's love and empowered by the Holy Spirit. Our perception of pneumatology should be constructively oriented toward justice and life for conviviality instead of the divinization of human beings.
The Context and Shape of Theological Education in Mozambique with Special Reference to Women
Authors: Schafroth Verena 
Published: July 2018

AbstractIn Mozambique, a marked increase in evangelical churches was recorded in the 1980s. This brought the need for pastoral training into sharp focus, and many new Bible schools were founded in the 1980s and 1990s. Yet, the shape and context of theological education remains rather different from other African countries, as Bible schools are mostly not accredited by the government and most schools train part‐time in the evening. As of 2017, religious studies cannot be found at universities, leaving theological training firmly in the hands of the churches and mission organizations. The training of women has become increasingly important, but they also face many challenges. To shed light on these challenges, I present the results of 52 interviews with female students at various Bible schools in Mozambique, ranging from lack of family support to the fact that theological training is perceived to be only for men and full‐time/ordained ministry.
Rethinking the Great Commission: Incorporation of Akan Indigenous Symbols into Christian Worship
Authors: Ossom‐Batsa George , Apaah Felicity 
Published: July 2018

AbstractSymbols are communicative tools with performative functions in all cultures. Apart from their decorative functions, non‐Christian symbols adopted into Christianity have had a tremendous impact on Christian life since the early times, especially in liturgical practices. Through Western missionary activities, Ghana inherited Christian biblical‐liturgical art as has been developed in the home countries of the missionaries. However, since the 1960s Adinkra symbols have been incorporated into Christian worship and theology, receiving attention within secular and religious circles because of their communicative potential. On the religious level, some churches have adopted them as logos or incorporated them into architectural designs and liturgical art. This paper seeks to investigate what motivates various missions to choose particular Adinkra symbol(s) and what they hope to achieve with them. Furthermore, it attempts a theological reflection on the communicative potential of artefacts in Ghanaian Christianity as a response to the “Great Commission. “We approach the subject from a historical, contextual, and theological perspective, using selected Roman Catholic and Methodist churches in Ghana as case studies. The study employed unstructured in‐depth interviews and photo elicitations to trace the relationship between visual arts and religion, with particular emphasis on Christian visual arts and how they have informed Christianity in Ghana.