bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adventitious viruses persistently infect three commonly used mosquito cell lines
Authors: Weger-Lucarelli James , Rückert Claudia , Grubaugh Nathan D. , Misencik Michael J. , Armstrong Philip M. , Stenglein Mark D. , Ebel Gregory D. , Brackney Doug E. 
Published: May 2018

AbstractMosquito cell lines were first established in the 1960’s and have been used extensively in research to isolate and propagate arthropod-borne (arbo-) viruses, study the invertebrate immune system, and understand virus-vector interactions. Despite their utility as anin vitrotool, these cell lines are poorly defined and may harbor insect-specific viruses that could impact experimental results. Accordingly, we screened four commonly-used mosquito cell lines, C6/36 and U4.4 cells fromAedes albopictus, Aag2 cells fromAedes aegypti, and Hsu cells fromCulex quinquefasciatus, for the presence of adventitious viruses. All four cell lines stained positive for double-stranded RNA by immunofluorescence, indicative of RNA virus replication. We subsequently identified viruses infecting Aag2, U4.4 and Hsu cell lines using untargeted next-generation sequencing, but not C6/36 cells. Sequences from viruses in the familiesBirnaviridae,Bunyaviridae, Flaviviridae,andRhabdoviridaewere abundant in the mosquito cell lines. PCR confirmation revealed that these sequences stem from active viral replication and/or integration into the cellular genome. Our results show that these commonly-used mosquito cell lines are persistently-infected with several viruses. This finding may be critical to interpreting data generated in these systems.
Determinants of livelihood choices and artisanal entrepreneurship in Nigeria
Authors: Igwe Paul Agu , Madichie Nnamdi O. , Newbery Robert 
Published: May 2018

Purpose
The purpose of this paper is to provide fresh insights into rural artisanal activities in a developing world context. It highlights key determinants of the decision to engage in an artisanal business and the challenges that impact upon the growth of these activities.

Design/methodology/approach
The study adopts a mix-method research approach to explore a rural setting where most respondents (81 per cent) combine farm and non-farm livelihood activities. Quantitatively, a multi-nominal regression is used to examine the determinants of diversified artisanal livelihoods. It modelled the differences between farming livelihoods that have not diversified, compared to those also involved in the artisanal activity or wage employment and the intensity of participation.

Findings
The findings show that nearly half of artisanal businesses (45.4 per cent) comprise only the owners and no employee, while 54.6 per cent employ one to three workers. Also, some artisanal ventures were more gender-specific than the gender-neutral activities. Other observations were in age (most artisans were under the age of 46 years) and vocational training (most were self-trained followed by a third receiving training only in specific areas such as technical works, building and construction and general trading apprenticeships).

Research limitations/implications
The study is based on a relatively small sample size of 306 business owners, which makes it difficult to generalise despite the persuasiveness of the observations made.

Practical implications
First, the use of econometric methods enabled the development of valid data sets (and various descriptive statistical and logit regression) to analyse determinants of the decision to engage in artisanal work, and the intensity of participation. Second, the ambiguity in categorising artisanal activities is unravelled. The study characterises the local artisanal sector and examines the intensity of participation. Without these, targeted support would remain elusive for practical and policy interventions.

Originality/value
Artisanal activities constitute a high proportion of small businesses in the study area – with more than half (54.2 per cent) of respondents being classified as artisans, yet it is an overlooked area of entrepreneurship. Highlighted here are both types of activities and challenges regarding better conceptualising the understanding of artisans and regarding this mostly unarticulated base of practice.
The impact of overseas human capital and social ties on Chinese returnee entrepreneurs’ venture performance
Authors: Ma Zhenzhong , Zhu Jinwei , Meng Yong , Teng Ying 
Published: May 2018

PurposeEntrepreneurship research clearly documents the importance of human and social capital and stresses the way in which entrepreneurs take advantage of their own social affiliations and network strategies in pursuit of their entrepreneurial goals, yet the research on returnee entrepreneurs’ human and social capital is not sufficiently studied in the international context, in particular when returnees’ overseas human capital and social capital may be a misfit with local business environment. Using the data from Chinese returnee entrepreneurs’ venture activities in China, the purpose of this paper is to examine the impact of returnee entrepreneurs’ overseas capital (human and social) and domestic capital (human and social) on their venture performance in China, and further explore the interaction effect of different social and human capital with China’s entrepreneurial environment.Design/methodology/approachThis study surveyed 500 start-up businesses created by returnee entrepreneurs in China to collect data. Self-administered questionnaires were used to collect data on their demographic information, the information about the human and social capital of these returnee entrepreneurs, including domestic and overseas capital, various performance measures, and other control variables ending up with 226 usable questionnaires.FindingsThe results show that Chinese returnee entrepreneurs’ overseas human capital and social capital, as well as their domestic social capital, but not domestic human capital, have a significant impact on their venture performance. In addition, while domestic entrepreneurial environment does not affect the impact of overseas human and social capital on venture performance, it does provide an important contextual setting for domestic capital to improve returnee entrepreneurs’ venture performance.Originality/valueThe findings help enrich the understanding of the dynamic interplays among Chinese returnee entrepreneurs’ domestic human capital and social capital, overseas human capital, and social capital, as well as the entrepreneurial environment for returnee entrepreneurs’ success, which makes an important contribution to the international entrepreneurship theory by showing that overseas human capital and social capital are not a misfit with local markets. It also provides empirical support for the mediating effect of entrepreneurial opportunity identification. The important role of entrepreneurial opportunity is empirically supported in an international context: entrepreneurship is all about the discovery of entrepreneurial opportunities and exploitation of this opportunity to create viable business entities for new products and services, even in the Chinese context, a culture which is very different from the ones where the entrepreneurship theory was developed.
Cultural configurations and entrepreneurial realisation
Authors: Torres Pedro , Augusto Mário 
Published: May 2018

Purpose
The purpose of this paper is to better understand the connection between culture and entrepreneurship in proposing and testing complex configurations of culturally endorsed implicit leadership theories (CLTs) and cultural practices that lead to entrepreneurial behaviour by studying entrepreneurial intentions (EI) and early-stage entrepreneurial activity (TEA) separately.

Design/methodology/approach
Using data from Globe Leadership and Organizational Behavior Effectiveness (GLOBE) and Global Entrepreneurship Monitor (GEM) studies, a sample of 44 countries, and a fuzzy-set qualitative comparative analysis, several models for EI and TEA were developed.

Findings
The main findings provide a way of distinguishing between complex antecedent conditions that are required for each stage of the entrepreneurial realisation. The results empirically show that there is no ideal context – the path to stimulate entrepreneurship that works best for one country does not necessarily works the same for other countries. There are multiple paths to achieve the desired outcome.

Research limitations/implications
The data from the GLOBE study were not completely up to date, the effect of which was minimised by considering data from GEM that respects temporal ordering. Nevertheless, data from GEM suggest that there is a degree of stability in the data over time. Future research could replicate this study with a larger selection of countries and with new data, collected in a different way. Additionally, the inclusion of CLTs proposed in this study opens new opportunities for future research, by providing a new angle to look at the entrepreneurial realisation process.

Practical implications
This study advances research into the association of culture and entrepreneurship, and develops testable models using a configurational approach, thus confirming the suitability of asymmetric configuration analysis for entrepreneurial research. The results expand an understanding of the entrepreneurial process by showcasing the different complex antecedent conditions for EI and TEA. Depending on a country’s cultural profile, policy-makers should invest in the dimensions that enable their society to align with the model that best suits their own culture. The obtained models offer a framework for evaluating new interventions that aim to develop entrepreneurial behaviour in a specific country.

Originality/value
Different configurations showcase that there are alternative paths to achieving high levels of EI and TEA. The differences among the possible configurations for each stage of the entrepreneurial realisation are uncovered. Country profiles are identified, quantified, and then compared providing guidance for policy-makers.
Does product design matter? Exploring its influences in consumers’ psychological responses and brand loyalty
Authors: Hsu Chia-Lin , Chen Yen-Chun , Yang Tai-Ning , Lin Wei-Ko , Liu Yi-Hsuan 
Published: May 2018

PurposeUnique product design is a highlight of sustainable branding. The purpose of this paper is to investigate whether product design affects customers’ psychological responses (i.e. cognitive and affective responses) to smartphones, and, in turn, affects their brand loyalty (i.e. attitudinal and behavioral brand loyalty), further advancing the knowledge of product design and brand management.Design/methodology/approachThis work used survey data from 456 Taiwanese with experience using smartphone. Structural equation modeling was employed to test the proposed model and hypotheses.FindingsThe results indicate that the product design significantly affects both cognitive response and affective response, which, in turn, significantly affect both attitudinal brand loyalty and behavioral brand loyalty. The findings also suggest that the moderating effect of product involvement on the relationship between product design and affective response is statistically significant, although it does not positively and significantly moderate the link between product design and cognitive response.Research limitations/implicationsThis study has two main limitations. First, this study was conducted in the context of smartphones, thus potentially constraining the generalization of the results to other industries. Second, the data in this study were obtained from a cross-sectional design.Practical implicationsThese findings can permit companies to generate more brand loyalty in their customers and guide their management of assets and marketing activities.Originality/valueThis paper presents new insights into the nature and importance of product design in brand value.
Mapping knowledge structure by keyword co-occurrence and social network analysis
Authors: Cheng Fei-Fei , Huang Yu-Wen , Yu Hsin-Chun , Wu Chin-Shan 
Published: May 2018

Purpose
The purpose of this paper is to present the knowledge structure based on the articles published in Library Hi Tech. The research hotspots are expected to be revealed through the keyword co-occurrence and social network analysis.

Design/methodology/approach
Data sets based on publications from Library Hi Tech covering the time period from 2006 to 2017 were extracted from Web of Science and developed as testbeds for evaluation of the CiteSpace system. Highly cited keywords were analyzed by CiteSpace which supports visual exploration with knowledge discovery in bibliographic databases.

Findings
The findings suggested that the percentage of publications in the USA, Germany, China, and Canada are high. Further, the most popular keywords identified in Library Hi Tech were: “service,” “technology,” “digital library,” “university library,” and “academic library.” Finally, four research issues were identified based on the most-cited articles in Library Hi Tech.

Originality/value
While keyword plays an important role in scientific research, limited studies paid attention to the keyword analysis in librarian research. The contribution of this study is to systematically explore the knowledge structure constructed by the keywords in Library Hi Tech.
The impacts of deviations from standard daily procedures on stock performance – a case study of Carnival Cruise Line
Authors: Wang Grace , Zeng Qingcheng , Ghoram Lawrence Cliff 
Published: May 2018

Purpose
In the USA, the cruise industry has generated more than $42bn in total economic activities, involving over 356,000 jobs. The largest and most aggressive operator is acknowledged as Carnival Cruise Line (CCL), with a 48.3 per cent market share including all subsidiary companies in 2013. CCL has had a strong track record of reliability and high quality; however, within the past decade, there have been several deviations from standard daily procedure that have altered the way CCL does business. When trying to interpret changes in company performance, it is important to include other factors that may have contributed to changes at the time of any given deviation.

Design/methodology/approach
The authors use time series empirical mode decomposition to visualize whether there are short- or long-term shocks to company performance in the wake of deviating events. Besides, a thorough analysis is carried out with multivariable linear regression to identify the factors that really impact CCL’s performance.

Findings
This case study shows the seasonal patterns of weather issues with the largest number of hurricanes and tropical storms taking place during the third quarter of each year.

Originality/value
Empirical results will enhance understanding of the industry with regard to such events. It will provide shareholders information and opinions to enhance their decision-making processes.
The study of sewing damage and defects in garments
Authors: Choudhary Awadhesh Kumar , Sikka Monica Puri , Bansal Payal 
Published: May 2018

PurposeThe purpose of this review paper is to define the dominating factors (such as fiber, yarn, fabric structure, sewing thread, sewing needle and machine parameters) that affect the seam damages and causing defects. It also describes the various explanations of sewing defects in garment production and critically analyzes them for optimum selection of parameters and speeds for minimizing such faults. Hence, the knowledge of various factors which affect the sewing damages/defects will be helpful for garment manufacturers/researchers to know influence of the parameters and control the quality of producing seam.Design/methodology/approachThis section is not applicable for a review paper.FindingsSewing damages such as needle cut and other sewing damages/defects are studied mostly in woven fabric. There are very few studies conducted on knitted fabric sewing damages/defects. The sewing damage problems do not have single solution that is capable of removing these damages in fabric. All the determined and affecting parameters related to fiber, yarn, fabric construction, sewing thread and sewing machine must be examined to design appropriate remedial measurement related to machine design, fabric parameters and sewing thread. This could help in minimizing or eliminating the needle cut and other sewing damage problems.Originality/valueIt is an original review work and is helpful for garment manufacturers/researchers to reduce the defects and be able to produce good quality seam.
Retracted: Blockade of ONECUT2 expression in ovarian cancer inhibited tumor cell proliferation, migration, invasion and angiogenesis
Authors: Lu Tongyi , Wu Binhua , Yu Yunfei , Zhu Wenhui , Zhang Simin , Zhang Yinmei , Guo Jiaying , Deng Ning 
Published: May 2018

One cut homeobox 2 (ONECUT2 or OC‐2) is a newly discovered transcription factor. Aberrant expression of OC‐2 is closely related to cell proliferation, migration, invasion, and angiogenesis. In this study, we found that OC‐2 expression was upregulated in ovarian adenocarcinoma cells, by Western blot analysis. The results of immunohistochemistry showed that the expression of OC‐2 was also increased in malignant ovarian cancer tissue. In order to explore the role of OC‐2 in the development of ovarian cancer, siRNAs that specifically targets OC‐2 were designed. The siRNA targeting OC‐2 could effectively inhibit the vascular endothelial growth factor A (VEGFA) expression, but silence and overexpression of VEGFA did not affect OC‐2 expression. In addition, OC2‐siRNA could block the proliferation, migration, and invasion, and inhibit epithelial–mesenchymal transition and the AKT/ERK signaling pathway, of human ovarian cancer cells in vitro. In a mouse model of ovarian cancer xenograft tumors, OC2‐siRNA could significantly inhibit tumor cell growth and the tumor inhibition rate reached approximately 73%. The results of immunohistochemistry showed that the densities of microvessels stained with CD31, the expression of OC‐2 and VEGFA were significantly decreased in tumors. These data indicated that OC‐2 was an upstream regulator of VEGFA and silencing OC‐2 could inhibit ovarian cancer angiogenesis and tumor growth.
Potential of electric bicycles to improve the health of people with Type 2 diabetes: a feasibility study
Authors: Cooper A. R. , Tibbitts B. , England C. , Procter D. , Searle A. , Sebire S. J. , Ranger E. , Page A. S. 
Published: May 2018

AbstractAimTo explore in a feasibility study whether ‘e‐cycling’ was acceptable to, and could potentially improve the health of, people with Type 2 diabetes.MethodsTwenty people with Type 2 diabetes were recruited and provided with an electric bicycle for 20 weeks. Participants completed a submaximal fitness test at baseline and follow‐up to measure predicted maximal aerobic power, and semi‐structured interviews were conducted to assess the acceptability of using an electric bicycle. Participants wore a heart rate monitor and a Global Positioning System (GPS) receiver in the first week of electric bicycle use to measure their heart‐rate during e‐cycling.ResultsEighteen participants completed the study, cycling a median (interquartile range) of 21.4 (5.5–37.7) km per week. Predicted maximal aerobic power increased by 10.9%. Heart rate during electric bicycle journeys was 74.7% of maximum, compared with 64.3% of maximum when walking. Participants used the electric bicycles for commuting, shopping and recreation, and expressed how the electric bicycle helped them to overcome barriers to active travel/cycling, such as hills. Fourteen participants purchased an electric bicycle on study completion.ConclusionsThere was evidence that e‐cycling was acceptable, could increase fitness and elicited a heart rate that may lead to improvements in cardiometabolic risk factors in this population. Electric bicycles have potential as a health‐improving intervention in people with Type 2 diabetes.
Executive function as a risk factor for incisor trauma
Authors: Nyquist Jillian M. , Phillips Ceib , Stein Margot , Koroluk Lorne D. 
Published: May 2018

AbstractBackground/AimExecutive function is the ability to guide behavior to achieve goals or complete tasks. This study explored the relationship between executive function, as assessed by the Behavior Rating Inventory of Executive Function Parent Form Questionnaire (BRIEF®) and incisor trauma.Material and MethodsThis study included children in the mixed dentition with recent incisor trauma (n = 28) and a control group (n = 30) without recent incisor trauma. Subjects' parents completed the BRIEF®, while a clinical examination assessed subjects' occlusal relationships. Parents also completed a custom questionnaire that investigated their child's medical history and daily activities. Fisher exact and unpaired t tests compared BRIEF® scores, occlusal characteristics, medical history, and reported daily activities of the 2 groups.ResultsThe trauma group had a greater percentage of participants with a Class II dental relationship (P = .01). There was no significant difference between groups with respect to mean BRIEF® t‐scores within the Global Executive Composite. There was a statistically significant difference between groups with respect to the percentage of subjects with clinically significant (≥65) BRIEF® t‐scores within the Inhibit (P = .05) and Emotional Control (P = .02) subscales and Behavioral Regulation Index (P = .02). There were no statistically significant differences between groups with respect to age, gender, overbite, overjet, medical history, body mass index, or daily activities.ConclusionsChildren in the mixed dentition with a Class II dental relationship are at greater risk for incisor injury, as well as those involved in outdoor activities. Specific executive dysfunctions such as impulsivity and poor emotional control may increase the risk for incisor trauma.
Revising ‘Bloody foreigners!’
Authors: Grossman Richard S. 
Published: May 2018

AbstractLeslie Hannah argues, among other things, that the series on par value of UK‐listed equities that I presented in an article published in the Economic History Review in 2015 is deeply flawed. Although I would quibble with some of Hannah's points, his main conclusion is correct: many of the series in ‘Bloody foreigners!’ are, in fact, flawed and require substantial revision. In this note, I explain the source of the errors and the steps I have taken to correct them in the preparation of subsequent work.
Marked accumulation of fluorodeoxyglucose and inflammatory cells expressing glucose transporter‐3 in immunoglobulin G4‐related autoimmune hepatitis
Authors: Araki Toshihiro , Arinaga‐Hino Teruko , Koga Hironori , Akiba Jun , Ide Tatsuya , Okabe Yoshinobu , Kuwahara Reiichiro , Amano Keisuke , Yasumoto Makiko , Kawaguchi Toshihiro , Sano Tomoya , Kondou Reiichiro , Kurata Seiji , Mitsuyama Keiichi , Torimura Takuji 
Published: May 2018

Immunoglobulin (Ig)G4‐related autoimmune hepatitis (AIH) is a recently proposed subtype that responds well to steroid treatment; however, its pathogenesis remains unclear. We report here a 65‐year‐old Japanese woman with skin itching and lip swelling. She had liver injury with jaundice, which persisted despite stopping anti‐allergic agents. Blood chemistry revealed highly elevated serum IgG and IgG4 (535 mg/dL) levels, and positive anti‐nuclear antibody. The diagnosis of AIH was based on liver biopsy. Notably, the IgG4+/IgG+ cell ratio was 85%. On fluorodeoxyglucose (FDG) positron emission tomography/computed tomography, robust signal intensity was found in the liver, and in enlarged lymph nodes and salivary glands with confirmed IgG4+ cell infiltration. Immunofluorescence analysis of the liver biopsy specimen indicated clear expression of glucose transporter‐3 (Glut‐3) in IgG4+ inflammatory cells infiltrating into the portal area. This is the first report of simultaneous strong accumulation of FDG and Glut‐3 expression in IgG4‐related AIH, which might aid in elucidating the pathogenesis of this disease.