bluuebunny/crossref_metadata_2025_split huggingface dataset:
Avant l’écriture, à côté du texte : listes et genèse littéraire
Authors: Zanardo Monica 
Published: February 2019

L’article porte sur les listes génétiques qui figurent dans les papiers autographes de plusieurs écrivains et qui sont destinées à disparaitre au fil de l’écriture. Nous proposons un classement fonctionnel des listes génétiques sur la base de leurs usages : aux listes « expansives » (qui sont progressivement développées au fil de l’écriture) s’opposent les listes « contractiles » (sur lesquelles les écrivains travaillent par sélection progressive des items). A côté de ces deux directions de dépassement de la liste, on trouve aussi les listes d’appui (qui se situent généralement « à côté du texte », car elles ne participent pas directement de sa genèse) et les listes de régie, visant à réorganiser la matière littéraire.
Evaluating the Adherence to Guidelines for Management of Acute Heart Failure in the Gaza Strip Hospitals: A Medical Chart–Based Review Study
Authors: Elshami Mohamedraed , Dabbour Reem , Alkhatib Mohammed , Abdalghafoor Tamer , Alaloul Enas , Habib Mohamed , Ismail Montaser , Bottcher Bettina 
Published: February 2019

AbstractObjective: To evaluate adherence of clinicians to the European guidelines for management of acute heart failure (AHF). Materials and Methods: This was a medical chart–based review study conducted from January to December 2016, including 200 medical records of patients admitted to two major hospitals in the Gaza Strip, Palestine. The AHF management was compared to the European Society of Cardiology (ESC) Guidelines, 2016. Results: The patients' mean age was 66.0 ± 13.0 years. A total of 100 patients (50.0%) were women and 192 (96.0%) had comorbidities including hypertension, diabetes, and heart disease. The most notable finding was that of a very poor standard of documentation, especially for vital signs. Patient management showed mostly moderate to good adherence to guidelines with 189 (94.5%) patients undergoing electrocardiogram, 90 (45.0%) echocardiography, 97 (48.5%) chest X-ray, and 79 patients of 167 (47.3%) receiving vasodilators appropriately. Good adherence was found in checking glucose levels, 176 (88.0%), and application of oxygen (100% with SpO2 &lt; 90%). Some aspects of care showed poor adherence, such as overuse of digoxin in 57 patients (28.5%), of which only 30 (53.4%) had atrial fibrillation and inappropriate use of beta-blockers in two patients who were hypotensive. Furthermore, brain natriuretic peptide was not used at all. Conclusion: The results of this study show suboptimal adherence to the ESC guidelines in management of AHF, reflecting the need to improve awareness of evidence-based medicine among clinicians.
Ingénierie, climatologie et topographie de l'être-dans-le-monde – Des îles pour penser l'architecture ?
Authors: Meziou Olfa Raja 
Published: February 2019

Abstract. This text is an architect's reading of the last volume of Peter Sloterdijk's trilogy Ecumes (Foam), particularly the two chapters “Insulations” and
“Indoors”. It raises the issue whether the atmospheric analysis that
Sloterdijk develops from his representation of the being-in-the-world and the
inhabitation can lead to a new understanding of space that would help reach
more habitable future spaces. It suggests that the metaphor of the island can
help construct some sort of an intermediary analysis and conception object :
the (new) machine-to-live-in. Through the exercise of the atmospheric
analysis, it suggests a new critical reading of the conception processes of
human spatiality, which gives a glimpse into the possibility of setting new
generators for contemporary space design.
INFLUENCE OF STRAIN-INDUCED CRYSTALLIZATION ON STRESS SOFTENING OF SULFUR CROSS-LINKED UNFILLED GUAYULE AND DANDELION NATURAL RUBBERS
Authors: Junkong P. , Matsushima Y. , Phakkeeree T. , Cornish K. , Ikeda Y. 
Published: February 2019

ABSTRACT
The stress softening behaviors of sulfur cross-linked unfilled guayule natural rubber (S-GR) and sulfur cross-linked unfilled dandelion natural rubber (S-DR) under cyclic deformation were characterized by simultaneous wide angle X-ray diffraction and tensile measurements under cyclic deformation. The behaviors were found to be affected by their strain-induced crystallization (SIC) phenomena and aggregated nonrubber components. The stress softening degree at stretching ratio = 8.0 of S-DR was almost two times larger than that of S-GR. Additionally, the hysteresis loss and residual strain of S-DR were much higher than those of S-GR in the same cycle. The key factors that caused the increase in their degree of stress softening were the increase in average volume and the decrease in average number of strain-induced crystallites upon cyclic deformation, not the insignificant decrease in crystallinity. The breakage of the aggregated nonrubber components is a main origin of stress softening behaviors for S-GR and S-DR because their SIC behaviors also were significantly influenced by the aggregates of nonrubber components in the rubber matrixes. Both the effects of nonrubber components and SIC on stress softening were more dominant in S-DR than in S-GR, probably owing to the larger amount of aggregated nonrubber components in the former than in the latter. The results will be useful in effectively using guayule and dandelion natural rubbers as alternatives to Hevea natural rubber in the rubber industry.
BIO-CACO3 FROM RAW EGGSHELL AS ADDITIVE IN NATURAL RUBBER LATEX GLOVE FILMS
Authors: Tangboriboon Nuchnapa , Takkire Rujika , Sangwan Watchara , Changkhamchom Sairung , Sirivat Anuvat 
Published: February 2019

ABSTRACT
Raw hen eggshell powder, a calcium carbonate source, was used as a biofiller in the natural rubber latex compound and latex glove film formation via dipping process. The powder was anticipated to improve the physical (smoothness and thickness of film) and mechanical properties (tensile strength and elongation at break) of latex film and to reduce the extractable protein content on film surface. Eggshell powder ground by a rapid mill was fine particles of approximately 37.48 μm in diameter, suitable for homogeneous and compatible addition into the natural rubber latex compound. Dipping hand mold into the natural rubber latex compound with 50 wt% eggshell added was the best formula to obtain a smooth, clear, thin film surface, with the tensile strength of 23.24 ± 0.745 MPa and the highest elongation at break of 723.99 ± 14.60%, along with a low protein content, a dense film without water leakage, and with a good contact angle. The natural rubber latex glove film possessed good physical-mechanical properties and a low protein content as the results of the raw eggshell powder added as a biofiller.
Educar para reconocer:
Authors: Rodríguez Almansa Andrés , Costa Casais Manuela , López Facal Ramón 
Published: February 2019

Una de las singularidades del paisaje costero de Galicia es la amplia presencia de depósitos edafo-sedimentarios cuaternarios, de extraordinaria calidad en cuanto a la información que aportan. Una diferencia respecto al ámbito atlántico europeo. Registran la memoria de la tierra y pueden contemplarse como archivos que documentan cambios paleo-ambientales a escala local, regional y global y contextos geomorfológicos relacionados con la historia humana.
Imbuido por una renovada concepción del patrimonio, que valora las formaciones naturales más allá de su apreciación estética, el pensamiento científico ha comenzado a considerar estos depósitos como un bien patrimonial. Sin embargo, se produce una total desconexión entre estas aspiraciones y el reconocimiento de administración y ciudadanía.
Desde la convicción de que solo se producirá un reajuste a través de una educación generadora de conciencia social sobre los paisajes geomorfológicos, en este trabajo se plantea la relevancia de una educación patrimonial de índole crítica; se propone un modelo de actuación focalizado en la formación inicial del profesorado y se avanzan algunos datos que muestren sus resultados
One of the distinctive features of the coastal landscape of Galicia is its great number of quaternary pedosedimentary deposits, which are of extraordinary quality in terms of the information which, they provide, making them stand out from the rest of the European Atlantic coast. They record the memory of the land and can be considered to be repositories documenting paleoenvironmental changes on local, regional and global levels, as well as geomorphological contexts related with human history.
Imbued with a renewed understanding of heritage, which values natural formations beyond the appreciation of their aesthetic aspect, scientific thinking has begun to consider these deposits as cultural assets. However, a total disconnection arises between these aspirations and the recognition of such assets by the political administration and citizens.
In the belief that a change in this situation will only be brought about via an education which generates a social conscience regarding geomorphological landscapes, this study examines the relevance of a form of heritage education which is critical in nature; an approach focused on initial teacher training is proposed and data showing the results of this approach are presented.
Investigación de impacto sobre la formación en mediación y educación en museos: análisis de la Web of Science
Authors: Alvarez-Rodríguez Dolores , Marfil-Carmona Rafael , Báez-García Cinta 
Published: February 2019

La mediación educativa en el ámbito de la Educación No Formal y de las industrias culturales es, cada vez más importante, especialmente a la hora de llegar con eficacia a los públicos y la ciudadanía por parte de las instituciones vinculadas al patrimonio, el arte y la creatividad. De forma específica, los museos requieren de una formación y capacitación en la función mediadora y educativa. Este trabajo, basado en una revisión bibliográfica de artículos en revistas de impacto, analiza las publicaciones científicas en la Web of Science (WOS) vinculadas a la formación de educadores en museos. El análisis cuantitativo y cualitativo de las características principales de estos contenidos nos lleva a afirmar que la educación en museos y patrimonio es una línea emergente de investigación, aunque se trata de un sector en el que existen dificultades para trasladar al mundo académico e investigador la riqueza y diversidad de la educación en museos. En concreto, la WOS no cuenta con un contenido destacado en la temática general de mediación en museos y, particularmente, de la formación de ese colectivo profesional. En la selección final de 51 artículos, las publicaciones procedentes de universidades o instituciones españolas tienen un peso destacado. En resumen, es imprescindible apostar por la presencia de la realidad profesional de los museos en los circuitos de investigación, mejorando la reflexión y el análisis sobre la preparación y capacitación de estos profesionales.
Educational mediation in non-formal education and cultural industries contexts is increasingly important, especially when institutions of heritage, art and creativity try to reach effectively the public and citizenship. Specifically, museums require training and instruction in mediation and the educational role. This work, based on a bibliographic review of articles in impact journals, analyses the scientific publications on the Web of Science (WOS) linked to the training of educators in museums. The quantitative and qualitative analysis of the main characteristics of these contents leads us to affirm that education on museums and heritage is an emerging line of research. Although it is a sector in which there are some difficulties translating the richness and diversity of education in museums to the academic and researcher world. In particular, the WOS does not have a prominent content in the general theme of mediation in museums and, in particular, the training of these professionals. In the final 51 articles selected, the publications coming from Spanish universities or institutions have an outstanding weight. In summary, it is necessary to support the presence of the professional reality of museums in academic research circuits, improving reflection and analysis on the preparation and training of these professionals.
Patrimonio, curriculum y formación del profesorado de Educación Primaria en México
Authors: Luna Úrsula , Vicent Naiara , Reyes Cabrera William , Quiñonez Pech Sergio Humberto 
Published: February 2019

Este trabajo busca conocer cuál es la presencia del patrimonio en el curriculum de Educación Primaria en México, para posteriormente analizar su incidencia en los programas y planes de estudio de la formación del profesorado de esta etapa. Para ello, se ha llevado a cabo un análisis de contenidos para la identificación y categorización de una serie de términos vinculados al patrimonio. Posteriormente, se ha realizado un análisis de frecuencias de estos términos tanto en la ley educativa vigente en México como en los planes de estudio de las licenciaturas de Educación Primaria. Por último, se ha analizado la correspondencia entre la presencia del patrimonio en el curriculum mexicano de Educación Primaria y los planes formativos de los futuros maestros. Los resultados muestran mayor presencia del patrimonio en el curriculum de Educación Básica, y una mayor correspondencia entre los contenidos de éste y la Licenciatura de Educación Primaria Intercultural Bilingüe. Además, la presencia de términos tradicionales es mayor en áreas como historia y artes, mientras que otros como identidad o tradición se presentan en áreas como la de lengua.
This work aims at getting to know which the presence of heritage in the Elementary Education curriculum in Mexico is, to ultimately analyze its impact in the programs and syllabuses in the formation of teachers at this stage. For this purpose, an analysis of contents has been carried out so as to identify and categorize a series of terms linked to heritage. Afterwards, an analysis of the frequency of use of these terms has been carried out, not only in the Education Law in force in Mexico, but also in the syllabuses of the degrees for Elementary Education. Lastly, a final analysis has been done regarding the correspondence between the presence of heritage in the curriculums and its presence in the formative plans for future Elementary School teachers. The results portray a greater presence of heritage in the Basic Education curriculum, and a bigger correspondence between its contents and that of the Intercultural Bilingual Primary Education Degree. On top of that, the presence of traditional terms is bigger in areas such as History and Art, whereas other terms such as identity or tradition are more prominent in areas such as Language.
Synergetic Functional Nanocomposites Enhance Immunotherapy in Solid Tumors by Remodeling the Immunoenvironment
Authors: Yang Linnan , Sun Jing , Liu Qiang , Zhu Rongrong , Yang Qiannan , Hua Jiahui , Zheng Longpo , Li Kun , Wang Shilong , Li Ang 
Published: February 2019

AbstractCheckpoint blockade immunotherapy has demonstrated significant clinical success in various malignant tumors. However, the therapeutic response is limited due to the immunosuppressive tumor microenvironment (ITM). In this study, a functional nanomaterial, layered double hydroxides (LDHs), carrying specific functional miR155 is developed to modulate ITM by synergistically repolarizing tumor associated macrophages (TAMs) to M1 subtype. LDH nanoparticles loaded with miR155 (LDH@155) exhibit superior ability in cellular uptake by murine macrophages, miR escape into the cytoplasm and TAMs specific delivery when introtumoral administration. Meanwhile, upon exposure to LDH@155, TAMs are significantly skewed to M1 subtype, which markedly inhibits myeloid‐derived suppressor cells (MDSCs) formation and stimulates T‐lymphocytes to secrete more interferon‐γ (IFN‐γ) cytokines in vitro. Introtumoral administration of LDH@155 reduces the percentage of TAMs and MDSCs in the tumor and elevates CD4+ and CD8+ T cell infiltration and activation, which can promote therapeutic efficiency of α‐PD‐1 antibody immunotherapy. Furthermore, it is found that LDH@155 significantly decreases the expression level of phosphorylated STAT3 and ERK1/2 and activates NF‐κB expression in TAMs, indicating that the STAT3, ERK1/2, and NF‐κB signaling pathways may involve in LDH@155‐induced macrophage polarization. Overall, the results suggest that LDH@155 nanoparticles may, in the future, function as a promising agent for cancer combinational immunotherapy.
Circle of Willis variations in migraine patients with ischemic stroke
Authors: Hamming Arend M. , van Walderveen Marianne A. A. , Mulder Inge A. , van der Schaaf Irene C. , Kappelle L. Jaap , Velthuis Birgitta K. , Ferrari Michel D. , Terwindt Gisela M. , Visser Marieke C. , Schonewille Wouter , Algra Ale , Wermer Marieke J. H. ,   the Dutch acute Stroke Study (DUST) investigators
Published: February 2019

AbstractObjectivesMigraine is a risk factor for stroke, which might be explained by a higher prevalence in anatomical variants in the circle of Willis (CoW). Here, we compared the presence of CoW variants in patients with stroke with and without migraine.Materials and MethodsParticipants were recruited from the prospective Dutch acute Stroke Study. All participants underwent CT angiography on admission. Lifetime migraine history was assessed with a screening questionnaire and confirmed by an interview based on International Classification of Headache Disorders criteria. The CoW was assessed for incompleteness/hypoplasia (any segment <1 mm), for anterior cerebral artery asymmetry (difference > 1/3), and for posterior communicating artery (Pcom) dominance (Pcom–P1 difference > 1/3). Odds ratios with adjustments for age and sex (aOR) were calculated with logistic regression.ResultsWe included 646 participants with stroke, of whom 52 had a history of migraine. Of these, 45 (87%) had an incomplete or hypoplastic CoW versus 506 (85%) of the 594 participants without migraine (aOR: 1.47; 95% CI: 0.63–3.44). There were no differences between participants with and without migraine in variations of the anterior or posterior CoW, anterior cerebral artery asymmetry (aOR: 0.86; 95% CI: 0.43–1.74), or Pcom dominance (aOR: 0.64; 95% CI: 0.32–1.30). There were no differences in CoW variations between migraine patients with or without aura.ConclusionWe found no significant difference in the completeness of the CoW in acute stroke patients with migraine compared to those without.
Incomplete estimates of genetic diversity within species: Implications for DNA barcoding
Authors: Phillips Jarrett D. , Gillis Daniel J. , Hanner Robert H. 
Published: February 2019

AbstractDNA barcoding has greatly accelerated the pace of specimen identification to the species level, as well as species delineation. Whereas the application of DNA barcoding to the matching of unknown specimens to known species is straightforward, its use for species delimitation is more controversial, as species discovery hinges critically on present levels of haplotype diversity, as well as patterning of standing genetic variation that exists within and between species. Typical sample sizes for molecular biodiversity assessment using DNA barcodes range from 5 to 10 individuals per species. However, required levels that are necessary to fully gauge haplotype variation at the species level are presumed to be strongly taxon‐specific. Importantly, little attention has been paid to determining appropriate specimen sample sizes that are necessary to reveal the majority of intraspecific haplotype variation within any one species. In this paper, we present a brief outline of the current literature and methods on intraspecific sample size estimation for the assessment of COI DNA barcode haplotype sampling completeness. The importance of adequate sample sizes for studies of molecular biodiversity is stressed, with application to a variety of metazoan taxa, through reviewing foundational statistical and population genetic models, with specific application to ray‐finned fishes (Chordata: Actinopterygii). Finally, promising avenues for further research in this area are highlighted.
Contrasting effects of habitat discontinuity on three closely related fungivorous beetle species with diverging host‐use patterns and dispersal ability
Authors: Kobayashi Takuya , Sota Teiji 
Published: February 2019

AbstractUnderstanding how landscape structure influences biodiversity patterns and ecological processes are essential in ecological research and conservation practices. Forest discontinuity is a primary driver affecting the population persistence and genetic structure of forest‐dwelling species. However, the actual impacts on populations are highly species‐specific. In this study, we tested whether dispersal capability and host specialization are associated with susceptibility to forest discontinuity using three closely related, sympatric fungivorous ciid beetle species (two host specialists, Octotemnus assimilis and O. crassus; one host generalist, O. kawanabei). Landscape genetic analyses and the estimation of effective migration surfaces (EEMS) method consistently demonstrated contrasting differences in the relationships between genetic structure and configuration of forest land cover. Octotemnus assimilis, one of the specialists with a presumably higher dispersal capability due to lower wing loading, lacked a definite spatial genetic structure in our study landscape. The remaining two species showed clear spatial genetic structure, but the results of landscape genetic analyses differed between the two species: while landscape resistance appeared to describe the spatial genetic structure of the specialist O. crassus, genetic differentiation of the generalist O. kawanabei was explained by geographic distance alone. This finding is consistent with the prediction that nonforest areas act more strongly as barriers between specialist populations. Our results suggest that differences in host range can influence the species‐specific resistance to habitat discontinuity among closely related species inhabiting the same landscape.
Krill faecal pellets drive hidden pulses of particulate organic carbon in the marginal ice zone
Authors: Belcher A. , Henson S. A. , Manno C. , Hill S. L. , Atkinson A. , Thorpe S. E. , Fretwell P. , Ireland L. , Tarling G. A. 
Published: February 2019

AbstractThe biological carbon pump drives a flux of particulate organic carbon (POC) through the ocean and affects atmospheric levels of carbon dioxide. Short term, episodic flux events are hard to capture with current observational techniques and may thus be underrepresented in POC flux estimates. We model the potential hidden flux of POC originating from Antarctic krill, whose swarming behaviour could result in a major conduit of carbon to depth through their rapid exploitation of phytoplankton blooms and bulk egestion of rapidly sinking faecal pellets (FPs). Our model results suggest a seasonal krill FP export flux of 0.039 GT C across the Southern Ocean marginal ice zone, corresponding to 17–61% (mean 35%) of current satellite-derived export estimates for this zone. The magnitude of our conservatively estimated flux highlights the important role of large, swarming macrozooplankton in POC export and, the need to incorporate such processes more mechanistically to improve model projections.