bluuebunny/crossref_metadata_2025_split huggingface dataset:
Child maltreatment and executive function development throughout adolescence and into young adulthood
Authors: Clinchard Claudia , Casas Brooks , Kim-Spoon Jungmeen 
Published: October 2024

Abstract
Child maltreatment impacts approximately one in seven children in the United States, leading to adverse outcomes throughout life. Adolescence is a time period critical for the development of executive function, but there is little research examining how abuse and neglect may differently affect the developmental trajectories of executive function throughout adolescence and into young adulthood. In the current study, 167 adolescents participated at six time points from ages 14 to 20. At each time point, adolescents completed behavioral tasks measuring the three dimensions of executive function (working memory, inhibitory control, and cognitive flexibility). Neglect and abuse in early life (ages 1–13) were reported at ages 18–19. Unconditional growth curve models revealed age-related improvement in all three executive function dimensions. Conditional growth curve models tested the prospective effects of recalled neglect and abuse on the developmental trajectories of executive function. The results revealed that neglect was associated with developmental changes in working memory abilities, such that greater levels of neglect during ages 1–13 were associated with slower increases in working memory abilities across ages 14–20. These findings highlight the adverse consequences of early neglect experiences shown by delayed working memory development during adolescence into young adulthood.
Failure to treat: an American policy perspective
Authors: Warburton Katherine 
Published: October 2024

Abstract
Throughout its two and a half centuries in existence, US mental health policy has repeatedly failed people living with schizophrenia. The failures are cyclical—the inhumane conditions uncovered in the first 75 years of existence were addressed with the construction of state asylums to deliver moral treatment. One hundred years later, the asylums were themselves revealed to be inhumane. Deinstitutionalization, the response to the failure of asylums starting in the 1960s, now drives outcomes such as homelessness, incarceration, and early death for people living with psychotic illnesses. In all cases, well-intentioned policy reform has failed at the level of implementation, largely due to a lack of accountability. The result has been a consistent failure to adequately treat people living with schizophrenia, which is now understood to be a highly treatable condition. As the country passes into a quarter millennium in existence, reform is once again underway. Unlike other points in history, there is good news. Other countries, such as Italy, have successfully leveraged reform to achieve greatly improved outcomes. Understanding US history and the successful implementation of policy change in other countries is imperative and teaches us that accountability in implementation is necessary to break the cycle of policy failure.
On the Foundations of Conflict-Driven Solving for Hybrid MKNF Knowledge Bases
Authors: KINAHAN RILEY , KILLEN SPENCER , WAN KEVIN , YOU JIA-HUAI 
Published: October 2024

AbstractHybrid MKNF Knowledge Bases (HMKNF-KBs) constitute a formalism for tightly integrated reasoning over closed-world rules and open-world ontologies. This approach allows for accurate modeling of real-world systems, which often rely on both categorical and normative reasoning. Conflict-driven solving is the leading approach for computationally hard problems, such as satisfiability (SAT) and answer set programming (ASP), in which MKNF is rooted. This paper investigates the theoretical underpinnings required for a conflict-driven solver of HMKNF-KBs. The approach defines a set of completion and loop formulas, whose satisfaction characterizes MKNF models. This forms the basis for a set of nogoods, which in turn can be used as the backbone for a conflict-driven solver.
Biogeochemical Reconstruction of Authigenic Carbonate Deposits at Methane Seep Site off Krishna‐Godavari (K‐G) Basin, Bay of Bengal
Authors: Pillutla S. P. K. , Peketi A. , Mazumdar A. , Sadique Mohd. , Sivan K. , Zatale Anjali , Mishra S. , Verma Swati 
Published: October 2024

AbstractActive and relic marine methane‐seep sites are widely distributed globally and are distinguished by distinctive geology, biogeochemistry, and ecosystems. The discovery of methane‐seep sites in the Krishna‐Godavari (K‐G) basin has created exciting new opportunities for methane‐seep research in the Bay of Bengal. In this study, we document the occurrence of authigenic carbonates, including micro‐crystalline aragonite crust (arg‐crusts) admixed with chemosynthetic shells and high‐magnesium carbonate tubular structures (HMC‐tube), from the methane‐seep site SSD‐045/4 in the K‐G basin. The δ13C values of HMC‐tubes (−54.5 to −46.2‰) and arg‐crusts (−57.6 to −34.8‰) indicate biogenic methane as the likely carbon source. Enhanced porewater alkalinity driving carbonate precipitation may be attributed to microbial‐mediated SO₄2−‐AOM processes. Additionally, δ13C values (−35.2 ± 8‰) of the residual organic matter within the carbonates suggest a contribution of methanotrophic bacterial biomass. The δ18Ocarb values of HMC and aragonite indicate methane hydrate degassing and crystallization pathways, respectively. Pelloid‐filled burrows suggest the reworking of shallow HMC deposit by burrowing organisms, whereas the polyphase cementations (aragonite and HMC) within burrows indicate early and burial diagenetic pathways. The wide range in ΣLREE/ΣHREE ratios and Ceanom values in arg‐crusts reflect micro‐spatial variations in redox conditions, likely due to cementation occurring in both open and closed diagenetic systems. In contrast, more constrained Ceanom values and ΣLREE/ΣHREE ratios in HMC tubes suggest persistent sulfidic conditions. Overall, these findings provide insights into the pathways of carbonate formation at the K‐G basin methane‐seep site, highlighting the complex interplay of microbial processes, fluid dynamics, and diagenetic alterations.
A Lake Biogeochemistry Model for Global Methane Emissions: Model Development, Site‐Level Validation, and Global Applicability
Authors: Tan Zeli , Yao Huaxia , Melack John , Grossart Hans‐Peter , Jansen Joachim , Balathandayuthabani Sivakiruthika , Sargsyan Khachik , Leung L. Ruby 
Published: October 2024

AbstractLakes are important sentinels of climate change and may contribute over 30% of natural methane (CH4) emissions; however, no earth system model (ESM) has represented lake CH4 dynamics. To fill this gap, we refined a process‐based lake biogeochemical model to simulate global lake CH4 emissions, including representation of lake bathymetry, oxic methane production (OMP), the effect of water level on ebullition, new non‐linear CH4 oxidation kinetics, and the coupling of sediment carbon pools with in‐lake primary production and terrigenous carbon loadings. We compiled a lake CH4 data set for model validation. The model shows promising performance in capturing the seasonal and inter‐annual variabilities of CH4 emissions at 10 representative lakes for different lake types and the variations in mean annual CH4 emissions among 106 lakes across the globe. The model reproduces the variations of the observed surface CH4 diffusion and ebullition along the gradients of lake latitude, depth, and surface area. The results suggest that OMP could play an important role in surface CH4 diffusion, and its relative importance is higher in less productive and/or deeper lakes. The model performance is improved for capturing CH4 outgassing events in non‐floodplain lakes and the seasonal variability of CH4 ebullition in floodplain lakes by representing the effect of water level on ebullition. The model can be integrated into ESMs to constrain global lake CH4 emissions and climate‐CH4 feedback.
Operational SYM‐H Forecasting With Confidence Intervals Using Deep Neural Networks
Authors: Collado‐Villaverde Armando , Muñoz Pablo , Cid Consuelo 
Published: October 2024

AbstractIn this study, we develop a robust real‐time forecast system for the SYM‐H index using Deep Neural Networks and real‐time Solar Wind measurements along with Interplanetary Magnetic Field parameters. This system provides not only one‐off forecasts but also quantile‐based confidence intervals, offering a range within which the observed SYM‐H values are expected to fall, enhancing forecast reliability and usability. The model is tested both on historical level 2 science‐ready data and on preliminary observations, which are closer to the operational environment that the model is expected to work on, demonstrating the model's robustness and practical utility in real‐time scenarios. The integration of quantile forecasts into SYM‐H prediction models represents a significant advancement, providing decision‐makers with more accurate and trustworthy information to manage the hazard of geomagnetic storms.
Graphene MEMS and NEMS
Authors: Fan Xuge , He Chang , Ding Jie , Gao Qiang , Ma Hongliang , Lemme Max C. , Zhang Wendong 
Published: October 2024

AbstractGraphene is being increasingly used as an interesting transducer membrane in micro- and nanoelectromechanical systems (MEMS and NEMS, respectively) due to its atomical thickness, extremely high carrier mobility, high mechanical strength, and piezoresistive electromechanical transductions. NEMS devices based on graphene feature increased sensitivity, reduced size, and new functionalities. In this review, we discuss the merits of graphene as a functional material for MEMS and NEMS, the related properties of graphene, the transduction mechanisms of graphene MEMS and NEMS, typical transfer methods for integrating graphene with MEMS substrates, methods for fabricating suspended graphene, and graphene patterning and electrical contact. Consequently, we provide an overview of devices based on suspended and nonsuspended graphene structures. Finally, we discuss the potential and challenges of applications of graphene in MEMS and NEMS. Owing to its unique features, graphene is a promising material for emerging MEMS, NEMS, and sensor applications.
Hypoxia-dependent recruitment of error-prone DNA polymerases to genome replication
Authors: Yehuda Ran , Dromi Ido , Levin Yishai , Carell Thomas , Geacintov Nicholas , Livneh Zvi 
Published: October 2024

AbstractHypoxia is common in tumors and is associated with cancer progression and drug resistance, driven, at least in part, by genetic instability. Little is known on how hypoxia affects Translesion DNA Synthesis (TLS), in which error-prone DNA polymerases bypass lesions, thereby maintaining DNA continuity at the price of increased mutations. Here we show that under acute hypoxia, PCNA monoubiquitination, a key step in TLS, and expression of error-prone DNA polymerases increased under regulation of the HIF1α transcription factor. Knocking-down expression of DNA polymerase η, or using PCNA ubiquitination-resistant cells, inhibited genomic DNA replication specifically under hypoxia, and iPOND analysis revealed massive recruitment of TLS DNA polymerases to nascent DNA under hypoxia, uncovering a dramatic involvement of error-prone DNA polymerases in genomic replication. Of note, expression of TLS-polymerases correlates with VEGFA (primary HIF1α target) in a database of renal cell carcinoma, a cancer which accumulates HIF1α. Our results suggest that the tumor microenvironment can lead the cell to forgo, to some extent, the fast and accurate canonical DNA polymerases, for the more flexible and robust, but low-fidelity TLS DNA polymerases. This might endow cancer cells with resilience to overcome replication stress, and mutability to escape the immune system and chemotherapeutic drugs.
Gamma irradiation green synthesis of (polyacrylamide/chitosan/silver nanoparticles) hydrogel nanocomposites and their using as antifungal against Candida albicans and anti-cancer modulator
Authors: Khalil Salwa A. , Awadallah-F Ahmed , Khaffaga Mervat R. , Fathy Rasha Mohammad , Kodous Ahmad S. 
Published: October 2024

AbstractSilver nanoparticles-loaded hydrogel nanocomposites are exploited for medicinal and pharmaceutical applications. Hydrogel nanocomposites were prepared from acrylamide (Am), chitosan (CS) and AgNO3 utilizing gamma rays. Diverse variables were applied in preparation of silver nanoparticles-laoded hydrogel nanocomposites of (PAm/CS)-AgNPs such as influence of radiation dose and influnece of CS concentration. Diverse techniques were utilized to characterize hydrogel nanocomposites; Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA), X-ray diffraction (XRD), Transmission electron microscopy (TEM), energy dispersive X-ray (EDX) and scanning electron microscopy (SEM). Results confirmed formation of silver nanoparticles-loaded hydrogel nanocomposites of (PAm/CS)-AgNPs. Antifungal activity of (PAm/CS)-AgNPs hydrogel nanocomposites on viability of C. albicans was esitmated. Results displayed the efficient microbial inhibition activity of treatment against C. albicans compared to control. Furthermore, (PAm/CS)-AgNPs hydrogel nanocomposite against cervical cancer HeLa cell line was investigated. Cytotoxicity of (PAm/CS)-AgNPs hydrogel nanocomposites on prior cancer cell line empolyed to prohibition of cell growth assesssed by MTT test. HeLa cancer cell is treated by (PAm/CS)-AgNPs for 48 h exposed a potential apoptotic activity by noticeable up-regulation of p53 gene expression. Moreover, anticancer activity was investigated by down-regulation of platelet-based growth variable receptor beta (PDGFR-β), Bcl2, Cathepsine, and MMP-2 gene expression. antioxidant activity was investigated and results showed antioxidant activity of (PAm/CS) hydrogel and (PAm/CS)-AgNPs hydrogel nanocomposite are 87.8% and 62.9%, respectively.
Gross morphological and ultrasonographic dimensions of normal feline kidney with reference to resistive index
Authors: Maher Mohamed Ahmed , Palacio Laura , Henao Juan C. , Elsharkawy Samar H. 
Published: October 2024

AbstractUltrasonography with color Doppler is the most quantitative analysis method for intra-renal parameters. There is a wide variation between authors in the measurement site and referencing the inter-lobar resistivity index (RI) in felines. Our objective is to morphometrically and ultrasonographically investigate the normal renal dimensions and vasculatures and draw up a normal reference value for the renal inter-lobar artery resistivity index (RI) using a Pulsed wave-Doppler ultrasonography. A total of twelve adult domestic cats were sedated and treated according to IACUC regulation guidelines to be examined using Doppler ultrasound. The same cats were used for morphometric investigation and divided into three groups regarding the used technique. The size difference between the right and left kidneys is slight, measuring 17 g (weight), 3.65 ± 0.06 cm (length), 2.54 ± 0.08 cm (width), and 2.21 ± 0.03 cm (thickness) for the right kidney, and about 15 g, 3.42 ± 0.06 cm, 2.32 ± 0.05 cm, and 2.13 ± 0.03 cm for the left one, respectively. There are three patterns of renal arteries’ point of origin. The mean RI values of both kidneys were 0.57 ± 0.08 (0.50–0.67) in the right kidney and 0.60 ± 0.08 (0.51–0.69) in the left kidney. The gross examination and ultrasonography measurements did not have a statistically different effect on the actual renal dimensions. Moreover, 0.69 is considered the standard resistivity index (RI) threshold of the feline inter-lobar artery with no correlation to the animal’s body weight.
Development of a novel immunocompetent murine tumor model for urothelial carcinoma using in vivo electroporation
Authors: Soleder Stefan , Gengenbacher Nicolas , Mogler Carolin , Eckstein Markus , Runge Anja , Kriegmair Maximilian C. , Augustin Hellmut G. 
Published: October 2024

AbstractA lack of advanced preclinical mouse tumor models impedes the progress in urothelial carcinoma research. We present here a novel fast, robust, reliable, and highly reproducible model for the genetic induction of bladder cancer in immunocompetent mice. Different sets of oncogenic transposons (Cmyc, Kras) and Cre drivers were transfected into the murine bladder wall of two different genetic backgrounds (Trp53fl/fl and BrafV600E, Ptenfl/fl, Ctnnb1exon3-fl/fl). Transfection was carried out using in vivo electroporation of the bladder after surgical exploration and transmural or transurethral intravesical plasmid injection. Up to 100% of animals developed urothelial carcinomas of the bladder. Time to tumor onset ranged from 16 to 97 days with a median of approximately 23 days in the fastest groups. Histological examination identified orthotopic urothelial carcinomas in most cases, in some experimental groups up to 100%. The resulting tumors were highly invasive and often metastatic. Metastases were found in up to 100% of tumor bearing mice per group. Taken together, this study establishes the proof-of-principle that in vivo electroporation can be versatilely employed as a reliable, fast, and robust method for the highly reproducible induction of urothelial carcinomas in the murine bladder wall. This novel murine tumor model could pave the way towards more easily modelling subtype specific urothelial carcinomas in mice.
Dr. Audrey Holland's Crazy Patchwork Quilt: A Thematic Analysis
Authors: Richardson Jessica D. , Dalton Sarah Grace Hudspeth , Hubbard Honey Isabel , Henry Maya 
Published: October 2024

AbstractDr. Audrey Holland was a friend to people with aphasia and related disorders, care partners, community advocates, students, clinicians, educators, researchers, and more. Her profound impact extended across these diverse communities within aphasiology and speech-language pathology. Through her words and deeds, Audrey established a rich legacy that continues to guide and inspire countless individuals. A careful examination of her contributions reveals a roadmap for those seeking to embark on a similar journey of compassion and influence. To pay tribute to our mentor and friend, we conducted a thematic analysis of her solo works to identify enduring themes, laugh-out-loud anecdotes, and poignant insights to share with her friends, colleagues, mentees, and even strangers who, after reading this article, will be touched and changed by her wisdom.
Abundance, size and biomass of long-spined sea urchins (Centrostephanus rodgersii) and red sea urchins (Heliocidaris tuberculata) in New South Wales, Australia
Authors: Blount C. , Worthington D. G. , Byrne M. , Chick R. C. , Organ K. , Knott N. , Andrew N. L. 
Published: October 2024

Context Detailed demographic information for the commercially harvested long-spined sea urchins (Centrostephanus rodgersii) and red sea urchins (Heliocidaris tuberculata) on nearshore reefs of New South Wales is unavailable. Aims This is the first detailed study of abundances and sizes of these sea urchin species on shallow reefs of New South Wales where the fishery operates. Methods Divers counted sea urchins and measured their sizes in transects in the nearshore mosaic habitat and in extensive barrens habitat at 51 sites along ~800 km of coast. Key results Centrostephanus was found at most sites in both habitats, whereas Heliocidaris was found at lower densities and at fewer sites. Heliocidaris was rare in the far south and in barrens habitat. Centrostephanus was, on average, smaller in barrens habitat than in the nearshore mosaic habitat, and size structures shifted towards smaller individuals from north to south. Conclusions Centrostephanus occurred at higher densities than did Heliocidaris and had a broader distribution along the coast and across the nearshore reefs where the fishery operates. Implications This study provides a historical baseline for these commercially and ecologically important species. The small biomass of Heliocidaris (~3% that of Centrostephanus) and its restricted distribution suggest it is vulnerable to overfishing.
The analysis of orientational metaphor of ‘Zhōng’ (中) in Chinese traditional classic The Doctrine of the Mean
Authors: Shan Weijia , Lin Zhengjun 
Published: October 2024

Abstract
This paper studies the orientational metaphor of zhōng (中, ‘middle’) and its cultural values behind this metaphor in
Chinese Traditional Classic The Doctrine of Mean. It is found that there are three metaphorical meanings for the
orientational metaphor of zhōng (中,
‘middle’), including “an emotion of calm.”; “a moderate degree” and “an ethical standard”. The ethical standard of
zhōng is the judge criteria for the Chinese traditional role schemas jūnzǐ (君子, ‘a person of noble character’) and xiǎorén
(小人,‘a person of petty character’). In addition,
the cultural values of Chinese society revealed by the ethical standard of zhōng (中, ‘middle’) are concluded systematically from the levels of
individual, family and state.
Improved breakdown voltage and dynamic Ron characteristics in normally-off GaN-based HEMTs featuring fully-recessed and bilayer-dielectric gate structure
Authors: Sun Nan , Dai Jianxun , Huang Huolin , Zhang Jiayu , Lei Yun , Wang Ronghua , Tao Pengcheng , Liu Yanhong , Song Shukuan , Ren Yongshuo , Cheng Wanxi , Liang Huinan 
Published: October 2024

Abstract
The degradation of dynamic on-resistance (R
on) is a major challenge in GaN-based high electron mobility transistors, which seriously affects their performance and reliability. The degradation area of dynamic R
on mainly comes from two aspects. One is the region below the gate that also affects the threshold voltage (V
th) of the devices. The other one is the interface region of the gate to drain access. The optimal device exhibits a V
th of 0.97 V, a small V
th hysteresis of only 20 mV, a high current density of 723 mA mm−1, and a breakdown voltage of 810 V which can be further boosted when additional field plate design is employed. It is found that when high voltage drain stress is applied, a positive V
th shift is induced, leading to a decrease in the effective gate driving voltage, and thus the dynamic R
on of the devices is increased. Of particular concern are the effects of dielectric layer and/or interface of the access region on the dynamic R
on degradation, which can be alleviated by removing the dielectric layer from the access region.
An FBG-based method for load measurement of a cylindrical rolling element bearing
Authors: Wang Xin , Liang Xihui , Wu Nan 
Published: October 2024

Abstract
Contact forces between raceways and rolling elements of a bearing stand as crucial operational aspects defining the bearing’s performance. While monitoring bearing load through load cells or strain gauges on the shaft or housing is feasible, it may not precisely reflect the distributed load transmitted by the rollers directly to the raceways. This paper introduces a method to calculate these contact forces, relying on a linear assumption correlating the loads to the measured strains on the outer race of a bearing. In our research, we conducted both static and dynamic tests on cylindrical roller bearings through simulations and experiments. We designed an experimental test rig to conduct both static and dynamic experiments and utilized FBG optical fiber sensors for contact force measurement in bearings due to their multiple advantages, including high sensitivity, resistance to corrosion and magnetic interference, and ease of installation on the bearing outer race due to their shape and size. Our findings indicate a consistent linear relationship between contact forces and strains measured on the bearing’s outer race. Furthermore, we calculated the linear coefficient K values from three test groups: static tests under simulation study, static tests under experimental study, and dynamic tests under experimental study. The K values obtained from static tests (simulation and experimental studies) and dynamic tests (experimental study) align consistently. Following this, we calculated contact forces in both static and dynamic experiments by multiplying the measured strains with K. Our calculations resulted in an error percentage of less than 2% for static tests and below 5% for dynamic tests, highlighting the accuracy of our approach in determining these contact forces.