bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sri Lanka Child Growth Cohort (SLCGC): a population-based study on growth faltering of children
Authors: Wickramasinghe Vithanage Pujitha , Liyanage Guwani , De Silva Weliange Shreenika , Walpita Yasaswi Niranjala , Siriwardena Indika , Partheepan Kunarathinam , Yogeswaran Suganya , Rowel Dhammica , Daniel Abner , Jayawickrama Hiranya Senani , Senarath Upul 
Published: November 2024

PurposeThis paper aims to describe the study design and baseline characteristics of the Sri Lanka Child Growth Cohort (SLCGC), which was established to assess the timing, pattern and determinants of growth faltering in infants and young children in Sri Lanka.ParticipantsA retrospective cohort study was conducted among term-born babies (≥37-week gestation), currently aged between 12 and 24 months. A sample of 1875 mother–child pairs were recruited using two-stage stratified cluster sampling method. Data on sociodemographic characteristics, pregnancy care, feeding practices, childhood illnesses and home risk factors were collected through direct interviews with the caregivers. Pregnancy-related data were obtained from the pregnancy record. Birth weight, serial weight and length records and growth pattern were extracted from the Child Health and Development Record. Current weight and length of the children were measured directly.Findings to dateThe SLCGC serves as a comprehensive cohort study with a countrywide distribution in Sri Lanka, covering the three main residential sectors, namely the urban, rural and estate sectors in equal proportions. The majority of mothers were housewives (76.8%) and aged <35 years (77.9%). The proportions achieved secondary education in mothers and fathers were 69.0% and 63.7%, respectively. Approximately 30% of mothers were overweight or obese, while 15% were underweight on entry to antenatal care. Of the children, 49.2% were girls, 42.5% were the first-born children in their family and 34.2% were born by caesarean section. Mean birth weight was 2917 g (SD 0.406), with the proportion of low birth weight (less than 2500 g) being 13%.Future plansThis data enables investigation of the effects of single exposures on child growth, as well as, more complex epidemiological analyses on multiple simultaneous and time-varying exposures. Data will be available for researchers for further analysis. The next wave of assessment is expected to be done after 12 months.
Analytical modelling techniques for enhancing tacrolimus dosing in solid organ transplantation: a systematic review protocol
Authors: Amooei Elmira , Buh Amos , Klamrowski Martin M , Shorr Risa , McCudden Christopher R , Green James R , Rashidi Babak , Sood Manish M , Hoar Stephanie , Akbari Ayub , Hundemer Gregory L , Klein Ran 
Published: November 2024

IntroductionTacrolimus is an immunosuppressant commonly administered in transplant recipients. Given its narrow therapeutic range and susceptibility to various influencing variables, determining its optimal dosage is challenging. This systematic review seeks to identify effective analytical modelling techniques and methods for optimal tacrolimus dose prediction in solid transplant recipients.Methods and analysisThis review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. The study will review the literature published from database inception to 11 March 2024, that assesses predictive models of tacrolimus dosing through analytical modelling techniques. We will include both randomised and non-randomised, as well as cross-sectional, qualitative and before-and-after studies and will perform our searches in four main databases—Ovid/MEDLINE, PubMed/MEDLINE, Scopus, Embase and Web of Science, and search engines including Centers for Disease Control (CDC) and Google Scholar. Papers that are not published in English or French are excluded from this study. A narrative synthesis and meta-analysis will be done if the extracted information permits such analysis. Conference abstracts will be ignored unless they are recent (published within 2 years of the search date).Ethics and disseminationEthics clearance is not required for this study as no primary data will be collected. The completed manuscript will be published, and the results of the study will be presented at conferences.Study registrationInternational Prospective Register of Systematic Reviews (PROSPERO), CRD42024537212.
Central venous catheter insertion profile and complications among neonates in Saudi Arabia: a cross-sectional study
Authors: Elabbasy Ahmed , Alkorbi Haifa Abdullah , Padua Ilene , Abuharb Abdullah Ibrahim , Alshedookhi Amjad Ahmad , Al-Shehri Hassan 
Published: November 2024

ObjectivesTo compare complications in neonates who had umbilical venous catheter (UVC) versus peripherally inserted central catheter (PICC), percentage of non-elective removal of central catheters, and to compare complications of PICC in the upper limb compared with the lower limb.DesignA prospective cross-sectional cohort study.SettingNeonatal intensive care unit (NICU) in Prince Sultan Military Medical City in Riyadh, Saudi Arabia.ParticipantsAll infants who are admitted to the unit requiring central catheter insertion were included in the study.Primary outcome measureComplications of central catheters in infants admitted to the NICU.ResultsA total of 415 central catheters were involved in this study (206 UVCs and 209 PICCs (85 in the lower limb, 99 in the upper limb and 25 in the head and neck). The median birth weight of the neonates was 1470 grams (1000–2215). Low birth weight was the most common reason for central catheter insertion, which accounted for 59.8%. Neonatologists were the main insertor for the majority of the cases. The median dwell days for the study sample were 11.00 (7.00–16.50) days. Complications were more common across PICC cases compared with UVC cases (p=0.001). There was non-elective removal of PICC (32.1%) compared with UVC (22.8%) (p=0.035). Phlebitis, occlusion, local infiltrate and leakage were more common in PICC compared with UVC (p<0.05). However, malposition was more commonly associated with the use of UVC (mainly to the liver) (p<0.01). Central line-associated bloodstream infection (CLABSI) rate in 1000.00 dwell days was higher in the upper limb 4.6 compared with the lower limb 2.72 but was not statistically significant (p=0.63), and there was no statistically significant difference in the proportion of other complications between the upper limb and the lower limb (p>0.05).ConclusionClose monitoring during extended dwell times is crucial. Our findings underscore the importance of raising awareness of CLABSI risk factors and adhering to best practices for central catheter maintenance. Healthcare professionals should be vigilant about the differences in complication rates between PICC and UVC, tailoring their approach accordingly.
Patients’ experiences with the application of medical adhesives to the skin: a qualitative systematic review
Authors: Hofman Hannelore , Duljic Tanja , Johansson Sara , Kottner Jan , Kinnaer Lise-Marie , Beeckman Dimitri , Eriksson Mats 
Published: November 2024

ObjectivesMedical adhesives provide securement of medical devices, facilitate skin protection and allow non-invasive monitoring. Application and removal of medical adhesives can result in pain, dermatitis, trauma or other skin lesions. Understanding patients’ experiences when subjected to medical adhesives will contribute to the improvement of clinical routines and the development and improvement of new adhesive technologies. A qualitative systematic review was conducted to identify patients’ experiences with the application of medical adhesives to the skin.DesignQualitative systematic review.Data sourcesCINAHL, EMBASE, MEDLINE and PsycINFO were systematically searched for records published between January 2012 and March 2024. Reference lists of systematic reviews and included articles were reviewed.Eligibility criteriaStudies published in Danish, Dutch, English, German, Norwegian and Swedish that collected qualitative data on the experience of patients with the application of medical adhesives to the skin were considered. There were no restrictions regarding age, gender or setting.Data extraction and synthesisStudy selection, data extraction and quality appraisal were independently conducted by two reviewers. The methodological quality of the studies under consideration was assessed using the Joanna Briggs Institute Critical Appraisal Tool for Qualitative Research. The extracted data were synthesised using meta-aggregation.ResultsNine studies describing patients’ experiences were included. The included studies only reflected experiences with wound dressings. Meta-aggregation of the extracted findings resulted in seven categories that were further synthesised into two synthesised findings: ‘strategies to alleviate pain during dressing changes’ and ‘dressing construction and characteristics’. The synthesised findings illustrate that patients experience pain during dressing change and removal and employ various strategies to alleviate this pain.ConclusionsPatients experience pain and discomfort when dressings are changed or removed. Future research should focus on enhancing both routines and technologies, with a particular emphasis on advancing skin-friendly adhesives to reduce unwanted side effects.PROSPERO registration numberCRD42023457711.
Factors affecting outcome of acquired comitant esotropia with restricted use of digital devices: ACEDD Study 3
Authors: Nishikawa Noriko , Iimori Hirohito , Kinouchi Reiko , Nishina Sachiko , Yoshida Tomoyo , Hikoya Akiko , Komori Miwa , Hieda Osamu , Goseki Toshiaki , Mori Takafumi , Morimoto Takeshi , Negishi Takashi , Shimizu Tamami , Shimizu Yukiko , Hayashi Shion , Sugiyama Yoshiko , Yokoyama Yoshimi , Kimura Akiko , Suzuki Hiroko , Suzuki Sadao , Azuma Noriyuki , Sato Miho 
Published: November 2024

ObjectiveThe objective of this study is to investigate factors associated with outcomes after 3 months of instructed usage of hand-held digital devices (DD) in patients with acquired comitant esotropia (ACE).Methods and analysisThis prospective multicentre observational study included patients with ACE, aged 5–35 years, who used DD within 1 year of onset and were followed up for clinical findings and instructed use of DD. The outcomes were classified into four groups: cured, improved, unchanged and worsened. After the analysis of group differences in the clinical and DD use-related factors by univariate analysis, we used ordinal logistic regression models to identify factors associated with favourable outcomes.ResultsOf 156 patients (mean age (SD): 16.4 (7.4) years), 10 (6%), 58 (37%), 67 (43%) and 21 (14%) were classified into the cured, improved, unchanged, and worsened, respectively. In the univariate analysis, consultation within 3 months of onset, small-angle strabismus at distance and good stereoacuity were associated with good outcomes. Ordinal logistic regression analysis on adjusting for age with stereoacuity or successful DD-use time halving showed that small-angle strabismus at distance (OR: 1.02, 95% CI 1.00 to 1.03, p=0.023), good stereoacuity (OR: 1.31; 95% CI 1.10 to 1.56; p=0.003) and successful halving of DD-use time (OR: 0.63; 95% CI 0.43 to 0.92; p=0.016) influenced favourable outcomes.ConclusionPatients with small-angle esotropia, good stereoacuity on consultation and success in halving DD-use time had a higher chance of recovery through instructional DD usage. Further studies using objectively measurable systems are needed to ensure the accuracy of DD-use time.
An overview of potentially toxic element pollution in soil around lead–zinc mining areas
Authors: Rouhani Abdulmannan , Gutiérrez Mélida , Newton Robert Ato , Al Souki Karim Suhail 
Published: November 2024

Metal mining activities have been major contributors of potentially toxic elements (PTEs) in the environment, leading to substantial soil pollution. One such example is lead–zinc mining around the world. Elevated concentrations of PTEs are commonly detected in nearby areas of both active and abandoned mines. This is primarily attributed to the release and dispersal of untreated waste materials from these mines into the surrounding environment. Mining-related soil pollution with PTEs can pose many different kinds of risks in a variety of contexts such as eco-toxicity, phytotoxicity, human health risk, as well as soil and water pollution. This review summarizes available data in the literature (2000–2023) on PTEs polluted soils originating from lead–zinc mining areas across the world. In this study, an attempt has been taken to evaluate the pollution level of PTEs in soils using collected data. The study shows the most polluted world regions are reported in Asia, followed by Europe and Africa, and only a few studies are reported in north, central and south America. The elements commonly analyzed in conjunction with Pb and Zn were Cd and Cu, whereas those responsible for increased pollution were Cd > As > Cu > Hg–Mn–Tl. Assessment of the pollution and health hazards has shifted to include a variety of quality indexes, including multivariate statistical analyses and microbial diversity.
Flavor factorization at two-loops
Authors: Larkoski Andrew J. 
Published: November 2024

AbstractRecently, a factorization theorem was proposed for partonic flavor evolution as defined by the net flavor of the Winner-Take-All axis of a jet. We validate the factorization theorem through explicit calculation at two-loop order, and in the process extract all anomalous dimensions and renormalization factors for any ultraviolet-to-infrared flavor transition at this order. These results can then be used to extract the renormalized hard function for flavored jet production at next-to-next-to-leading order for any process of interest.
Advancing Cancer Prevention through an AI-Based Integration of Traditional and Western Medicine
Authors: Zhang Peng , Zhang Qian , Li Shao 
Published: November 2024

Summary:
Traditional Chinese medicine has accumulated a wealth of experiences in individualized cancer prevention and serves as a complement to Western medicine. We propose an artificial intelligence–based integration of traditional and Western medicine as a new paradigm for cancer prevention, encompassing cancer risk screening and preventive intervention, which will provide new solutions for cancer prevention and offer fresh perspectives for traditional medicine research worldwide.
Building an Organ-Wide Macroscopic View of Cancer Hallmarks
Authors: Liu Suling , Wang Yuan , Feng Jiawen , Liu Zhihua , Zhou Shengtao 
Published: November 2024

Summary:
Despite an increasingly detailed understanding of cancer hallmarks at molecular or atomic resolution, most studies, however, fall short of investigating the systemic interactions of cancer with the human body. We propose to investigate the hallmarks of cancer from an organ-wide macroscopic view, discuss the challenges in preclinical and clinical research to study the cross-organ regulation of cancer together with potential directions to overcome these challenges, and foresee how this holistic view may be translated into more effective therapies.
From the Jordan to Mt. Ebal and Back
Authors: Segal Michael 
Published: November 2024

Abstract
This study explores the textual dynamics both within and between the law in Deut 27 and the narratives in Josh 3–4 and 8. It includes original analyses of: (a) the narrative of the Jordan crossing and its internal contradictions and ambiguities; (b) the internal rewriting and textual developments of the law in Deut 27:1–8; (c) the establishment of the altar in Josh 8:30–35 (MT), and its transfer to the Jordan crossing scene in 4QJosha; (d) the textual development of Deut 11:29–30; (e) the contribution of rabbinic literature towards elucidating the processes analyzed above; (f) the exegetical background of the so-called “Gerizim Composition” in SP, unrelated to sectarian concerns. These developments illustrate the dynamic interplay between literary history, transmission, and interpretation, and they underscore the fundamental importance of exegesis as a catalyst in these processes.
Conflicting Islamic Governmentality
Authors: Bekkaoui Hamza 
Published: November 2024

Abstract
In October 2021, Imam Mohamed Toujgani, a Moroccan who had resided in Belgium for nearly 40 years, was banned from the Schengen area for a decade. He was accused of espousing anti-Semitic views and having ties to Moroccan intelligence, posing a threat to societal harmony. This article critically examines the ban by putting it within the context of Europe’s securitisation of Islam. It explores Toujgani’s theological and social views, highlighting his promotion of dual belonging – a notion supported by the works of scholars such as Thijl Sunier on Islam in Europe. Employing Michel Pêcheux’s relational discursive approach, this study argues that Toujgani’s deportation risks deepening social divisions, potentially escalating conflicts rather than mitigating them.
High throughput sequencing reveals alterations in B cell receptor repertoires associated with the progression of hepatic cirrhosis to hepatocellular carcinoma
Authors: Zhao Yingying , Wang Fengyan , Lei Xiaofei , Li Ziqiang , Cao Qiwei , Jiang Runze , Xu Changqing , Li Kun 
Published: November 2024

Background: Hepatocellular carcinoma (HCC) is developed as a consequence of chronic liver cirrhosis, and both diseases are difficult to diagnose and differentiate. Accurate noninvasive biomarkers for HCC and liver cirrhosis are urgently needed. Methods: Here we used high-throughput sequencing to characterize the B cell receptor (BCR) repertoires from 36 HCC tumor samples and 10 liver cirrhosis (LC) tissue biopsies to understand the immune alterations during hepatic carcinogenesis. Results: The principal components analysis (PCA) showed that the pattern of BCR in HCC was distinct from that in LC. As measured by Clonality and Shannon indexes, the diversity of BCR repertoire was significantly lower in HCC than in LC (P < 0.01). Conclusion: Our results corroborated that the BCR diversity and composition could be closely correlated with hepatic carcinogenesis. And BCR repertoire may be used to predict the progression of HCC and design targeting immunotherapy in the near future.
Pelvic osteotomy for pelvic canal stenosis after malunion pelvic fractures in cats
Authors: Suzuki Ryoichi , Shimada Masakazu , Fukuda Hideyuki , Munakata Shuntaro , Kamijo Keiji , Yamaguchi Shinya , Hara Yasushi 
Published: November 2024

Objectives The aim of this study was to assess the efficacy of pelvic osteotomy and ventral fixation of the ischium using cortical screws and polymethylmethacrylate (PMMA) for feline pelvic canal stenosis (PCS) associated with malunion after conservative management of pelvic fractures. Methods Surgical pelvic enlargement was performed for PCS in six cats. The medical records, including information on the patients, surgical procedures, defecation and complications, were reviewed. The sacral index (SI) and colonic:lumbar:vertebral ratio (CLVR) were evaluated based on pre- and postoperative radiographs. Results This study included five castrated male cats and one spayed female cat. Postoperative improvements in constipation and defecatory difficulty were noted in all cases. The postoperative SI was significantly higher (mean 0.93, range 0.72–1.13) than the preoperative SI (mean 0.59, range 0.45–0.74) ( P <0.001). However, no statistically significant change was found in the CLVR preoperatively and up to 3 months postoperatively. A successful union of the ilium was observed, without implant failures. One case developed necrosis of the pubic surgical wound. Conclusions and relevance This study indicated the potential benefits of pelvic osteotomy and ventral fixation of the pelvic floor using screws and PMMA for achieving pelvic cavity enlargement in treating feline PCS associated with defecatory problems.
Design of collectors in centrifugal spinning: Effect on the fiber yield and morphology
Authors: Naseri Joda Nasrollah , Ince Ahmet Erdem , Rihova Martina , Pavlinak David , Macak Jan M 
Published: November 2024

Centrifugal spinning is an increasingly popular and viable method to produce fibers of different compositions. However, there are still aspects to investigate and improve in the centrifugal spinning process, such as optimizing the fiber yield and obtaining defect-free fiber morphology. To address this gap, the effects of the collectors on the fiber yield and their morphology were investigated in this work. An aqueous solution with 18 wt% of PVP and two needles (18G and 21G) with different diameters and three different spinning speeds (5000, 7000, and 9000 RPM) were used to explore a set of fiber collectors with various collector spacing (1, 3, 6, 12, and 18 cm distance between the collectors’ bars). The results of the experiments showed that fiber collectors affect the yield of the process and the fiber morphology to some (non-negligible) extent. Denser collectors enabled higher yield, thus reducing the waste, and positively affecting the beading of fibers. The knowledge obtained in this work about the influence of collectors on the centrifugal processing of basic polymers can be with an advantage applied to the processing of different polymers and needles used within the centrifugal spinning process.
Brief communication: The cohort of women prescribed HIV PrEP at the Veterans Health Administration
Authors: Keddem Shimrit , Broderick Kaitlyn , Van Epps Puja , Roberts Christopher B. , Chhatre Sumedha , Beste Lauren A. 
Published: November 2024

AbstractThe goal of this study was to describe the cohort of women prescribed PrEP at the Veterans Health Administration. We used a cross-sectional study of electronic health record data. We used descriptive statistics and calculated estimated average percent change by year of prescription. A total of 417 women were prescribed PrEP over the study period. The most substantial change over time in PrEP prescribing occurred among women aged 18–24, in Other race group, and in the Western US. Though PrEP prescribing increased since its approval, more research is needed to identify barriers and expand PrEP access for women Veterans.