bluuebunny/crossref_metadata_2025_split huggingface dataset:
PO-203 Across generations maternal exercise in hypoxic environment on mitochondrial biosynthetic factors in rat skeletal muscle
Authors: Quan Helong , Zhang Yong , Shan Zhouxiang , Ji Lei , Lim Changhyun , Kim Changkeun 
Published: October 2018

Objective Environmental and maternal exercise experienced even during the very earliest stages of life has the potential to cause developmental changes.The growing evidence demonstrated that diverse environmental stressors affect offspring in variousaspects in early stage of lifeand can be transmitted directly or indirectly by both parental lines.The purpose of the present study was to investigate the effect of across generations maternal exercise training under the hypoxic environment on mitochondrial biogenesis and angiogenesis related protein expressions of skeletal muscle in offspring ofmultiple generations.
Methods The experimental groups were divided into four groups as NCON (control in normoxia), NEXE (exercise in normoxia), HCON (control under hypoxia), HEXE (exercise under hypoxia), and studied for three generations. Exercise groups were run on animal treadmill at 60%-75% VO2maxfor one hour per day, five times per week for 10 weeks (seven weeks before conception and during conception for three weeks). Animals were sacrificed at a given time table and assayed mitochondrial biogenesis and angiogenesis related protein expressions using western blotting.
Results The major findings from the present study were firstly, maternal exercise training before and during conception under hypoxic environment increase in mitochondrial biogenesis and angiogenesis related proteins expressions in both maternal and offspring skeletal muscles, secondly, long term of exposure to hypoxic environment without exercise training increase in mitochondrial biogenesis and angiogenesis related proteins expressions in offspring skeletal muscles, and further increased when exercise training performed at hypoxic environment, lastly, there was no cumulative benefit by consecutively exposure for three generations under hypoxic environment, which is indicating world winning runners from high altitude dwellers may not relay on the duration of sojourn under hypoxic environment, but rather selection and training related factors.
Conclusions In summary, maternal exercise training before and during conception under hypoxic environment increase in mitochondrial biogenesis(PGC-1α, COX-Ⅳ, NRF-1, mtTFA) and angiogenesis(HIF-1α, VEGFtotal) related proteins expressions in both maternal and offspring skeletal muscles, especially exercise training stimulated the protein expressions under hypoxic environment than normoxic condition. Therefore, exercise capacity may be endowed by both hypoxic environment and exercise training at hypoxic environment.
PO-207 Effect of exercise intensity and diet on Glucose Metabolic factors in T2DM rat skeletal muscle
Authors: Ji Lei , Quan He Long , Kim Chang Keun , Yoon Chung Su 
Published: October 2018

Objective This study was to examine the effect of different exercise intensity and diet on the expression of the metabolism related factors in T2DM rat skeletal muscles.
Methods Diet induced T2DM rat by a combination of low dose streptozotocin (STZ: 40mg/kg) and feeding of a high fat diet used as experimental animals. The rats trained on the treadmill for 8 weeks with low (40% max）and high (80% max) intensities of exercise on the treadmill for 8 weeks. The soleus (SOL) and extensor digitorum longus (EDL) muscles were excised. The western blotting was performed for the expression of AMPK, p-AMPK, PGC-1α，and GLUT-4 proteins.
Results The expression of AMPK, p-AMPK, PGC-1α，and GLUT-4 proteins in SOL and EDL muscles were higher in both training groups compared to the non-training groups. The AMPK was differently expressed to the recruitment pattern of muscle group during exercise; expressed higher in SOL during low intensity of exercise and also highly expressed in EDL during high intensity of exercise, whereas the PGC-1a was expressed a contrast phenomenon to AMPK expression in both muscle groups. The expression of p-AMPK in both muscle groups was higher in low intensity of exercise and normal diet groups than in high intensity of exercise and high fat groups. The AMPK, p-AMPK, PGC-1α，and GLUT-4 protein expression demonstrated significantly higher in normal diet with endurance training group than in high fat diet with endurance training group.
Conclusions In summary, the expression of AMPK, p-AMPK, PGC-1α，and GLUT-4 proteins was differed with exercise intensities, diet and the type of muscles. These results indicated that the endurance training improved the insulin sensitivity according to the exercise intensity and diet in T2DM rats.
PO-210 Analysis on the Hotspot and Content of Exercise Therapy for the cerebral oxygen in Foreign Countries——Based on Visualization Research of Scientific Knowledge Map
Authors: Guo Xiaozheng , Wang Xing 
Published: October 2018

Objective To analyze the hotspot of exercise therapy for cerebral oxygen .
Methods This study is based on academic literature between1982-2017，which are retrieved from Web of Science. The author uses the software of CitespaceIII to make visual analysis for1701 literatures.
Results There has been a steady growth in the publications， countries with most publications include American， Japan，England ,Germony； research institutions are mainly composed of universities in Europe and America； authors forms a major cooperative team but with no obvious cross regional and institutional cooperation；the research focus on the the influence of cerebral blood flow and metabolic、the pressure of carbon dioxide on cerebral oxygen during exercise which pay close attention to cognition； research hotspot is mainly concentrated on the link among cerebral blood flow 、metabolism、automatic control of the brain 、cognition and cerebral oxygen .
Conclusions in the individuals of cardiovascular diseases research hotspot reveals low to moderate exercise is a better way to improve cognition in view of cerebral oxygen.
GİLABURU (VIBIRNUM OPULUS L.) MEYVESİNDEN FENOLİK BİLEŞİKLERİN ULTRASON DESTEKLİ EKSTRAKSİYONU
Authors: ŞAKIYAN DEMİRKOL Özge , İŞCİ YAKAN Aslı , ALİFAKI Yaşar Özlem 
Published: October 2018

Bu çalışmanın amacı gilaburu (Viburnum opulus L.)
meyvesinden fenolik bileşiklerin ultrason destekli ekstraksiyon sistemi ile
elde edilmesidir. Gilaburu meyvesinde bulunan yüksek miktardaki fenolik
bileşikler, hassas yapıları nedeniyle kolayca bozulabilmektedirler. Bu nedenle,
ekstraksiyon yöntemi olarak fenolik bileşiklere en az düzeyde zarar verecek
yenilikçi teknolojiler önem kazanmaktadır. Çalışmada, üç farklı katı:solvent
oranı (5:100, 10:100, 15:100) ve 6 farklı işlem süresi kullanılarak (1 dk , 10 dk, 20 dk, 30 dk, 60
dk, 120 dk) su ile ekstraksiyon işlemi gerçekleştirilmiştir. Bağımlı
değişkenler olarak toplam fenolik madde miktarı, antioksidan aktivite ve renk
değerleri belirlenmiştir. Toplam fenolik madde miktarı değerlerine göre optimum
katı: solvent oranı ve optimum ekstraksiyon süresi sırasıyla 5:100 ve 60 dakika
olarak bulunmuştur. Ek olarak L*, a*, b* ve toplam renk farkı değerleri toplam
fenolik madde miktarlarıyla yüksek oranda pozitif korelasyon göstermiştir.
Hubungan kebiasaan merokok dan akne vulgaris pada remaja usia 15-17 tahun
Authors: Prakasita Cintantya , Meiyanti Meiyanti 
Published: October 2018

LATAR BELAKANGAcne vulgaris merupakan penyakit self-limiting pada folikel pilosebasea yang sering ditemukan pada remaja. Prevalensi acne vulgaris terbesar terdapat pada remaja usia 16-18 tahun, yaitu sebesar 90%. Kejadian acne vulgaris disebabkan oleh berbagai faktor. Faktor yang berkaitan dengan patogenesis timbulnya acne vulgaris antara lain produksi sebum, jumlah Propionibacterium acne, kadar hormon androgen, stres psikis, usia, ras, familial, makanan, cuaca, dan rokok. Hasil penelitian sebelumnya tentang hubungan kebiasaan merokok dan acne vulgaris menunjukkan hasil yang belum konsisten. Penelitian ini bertujuan untuk mengetahui hubungan kebiasaan merokok dengan acne vulgaris pada remaja usia 15-17 tahun.
METODEJenis penelitian ini merupakan observational analitik dengan pendekatan cross sectional. Penelitian dilakukan pada 69 remaja usia 15-17 tahun di wilayah Tomang, Jakarta Barat. Sampel dipilih secara consecutive non random sampling. Pemeriksaan acne vulgaris dilakukan oleh dokter spesialis kulit dan data kebiasaan merokok diperoleh dengan pengisian kuesioner. Analisis data menggunakan SPSS versi 24.0. HASILPada penelitian ini melibatkan 69 subyek yang mengalami acne vulgaris. Tiga puluh empat subyek berumur 15 tahun dan 35 subyek berumur 16 tahun. Empat puluh subyek berjenis kelamin perempuan dan 29 subyek laki-laki. Lima belas subyek memiliki kebiasaan merokok. Empat puluh delapan subyek mengalami acne vulgaris derajat ringan. Hasil uji Fisher tidak memperlihatkan hubungan merokok dengan acne vulgaris (p=1.000).
KESIMPULANTidak terdapat hubungan antara kebiasaan merokok dengan acne vulgaris.
Some Notes about Arrangements of Points on Quadrics
Authors: Seliverstov A. V. 
Published: October 2018

It is considered the minimization of a quadratic polynomial on the set of all points of a multidimensional space, coordinates of which are either zero or one. Some restrictions are imposed on the arrangement of the minimum points when there are many such points.combinatorial optimization, quadratic programming, empty quadric, polytope, facet
Evaluation of mRNA Expression Levels of TNFα, TNFR1 and IL1β in Lung Tissue 20 Years after Sulfur-mustard Exposure
Authors: Eghtedardoost Marzieh , Mohammad Hassan Zuhair , Ghazanfari Tooba , Sadeghipour Alireza , Ghanei Mostafa 
Published: October 2018

Despite many years having passed since exposure to sulfur mustard (SM) gas, there are many exposed subjects who are still suffering from delayed pulmonary complications. The levels of pro-inflammatory cytokines in the lung of these subjects have not been investigated in delay phase. In this study, we evaluated mRNA expression of pro-inflammatory cytokines (tumor necrosis factor alpha (TNFα), tumor necrosis factor receptor type 1 (TNFR1), and interleukin 1 beta (IL-1β) ) in lung biopsy of SM-exposed subjects and compared them with control (non-exposed) subjects. We used formalin-fixed, paraffin-embedded (FFPE) tissue for this purpose.
Lung FFPE blocks of SM-exposed subjects (30 samples) and a control group (30 samples) were collected from archival pathology department. The total mRNA of FFPE tissues were extracted and the mRNA expression of pro-inflammatory cytokines were determined by quantitative Real Time PCR (RT-qPCR). The obtained results from two groups were compared to each other and non-parametric statistical analyses were carried out on them.
Our studies showed that the mRNA expression of TNFα, TNFR1 and IL-1β in lung tissue of SM injured and control people have no significant difference (p-value= 0.159, 0.832 and 0.314 respectivly). TNFR1 showed direct correlation with TNFα (r=0.867, p=0.002) and IL-1β (r= 0.65, p=0.006).
The evaluation of mRNA expression in pro-inflammatory cytokines in lung of SM-exposed subjects after 20 years showed that these mediators are similar to those of non-exposed group and there was no acute inflammation in lung of these patients.
The relationship between fibrinogen to albumin ratio and carotid artery disease in patients with carotid endarterectomy and patients with non severe carotid artery stenosis
Authors: ÖZSİN Kadir Kaan , SANRI Umut Serhat , TOKTAŞ Faruk , YAVUZ Şenol 
Published: October 2018

Aim: To investigate the relationship
between fibrinogen to albumin ratio
(FAR) and carotid artery stenosis (CAS). Material and Methods: This study
included patients who underwent carotid endarterctomy
(CEA) as CEA group and unoperated patients who have CAS less than 50% as non-surgical group. CAS was
diagnosed with history and physical examination followed by doppler
ultrasonography and carotid angiography. All data retrieved retrospectively
from the hospital medical files. Hematologic parameters were measured and
recorded. In addition, FAR was calculated.Results: Fifty patients were included
in CEA group (70.0 % male, mean age: 71.0 ± 7.7 years) and 60 patients were
invluded in non-surgical group (70.0 % male, mean age: 63.9 ± 8.0 years). In
logistic regression analysis advanced age, presence of coronary artery disease
and FAR were identified as an independent predictor of
the development of CAS. In Receiver operating characteristic (ROC) curve
analysis, for predicting development of CAS, there were 68.0% sensitivity and
65.0% specificity for FAR (area under the curve [AUC]: 0.669, 95% CI:
0.566-0.771, log rank p = 0.002).

Conclusion: We found that FAR were
identified as an independent predictor of the development of CAS. FAR could be
a potential marker on carotid atherosclerosis in patients. But there is a need
large studies including all cardiovascular diseases.
KRITICKÉ ČÍTANIE LITERÁRNEJ TVORBY VÍŤAZOSLAVA HRONCA Z ASPEKTU JEJ INTERTEXTUÁLNEHO CHARAKTERU
Authors: Svetlik Adam A. 
Published: October 2018

V príspevku som analyzoval monografiu Maríny Šimákovej Spevákovej, v ktorej táto literárna kritička dôkladne interpretovala celkové literárne dielo najvýznamnejšieho súčasného slovenského vojvodinského spisovateľa Víťazoslava Hronca v kontexte jeho intertextuálneho rázu. Pritom som sa zvlášť zameral na problematiku samotnej intertextuality, predovšetkým na jej implicitný respektíve explicitný charakter, najviac však na tzv. teóriu citátovosti, ktorú Šimáková Speváková vo svojom výskume dôsledne aplikovala. Súbežne s touto teoreticko-metodologickou problematikou analyzoval som i kritičkinu dôkladnú interpretáciu básnického, prozaického a autoreferenčného diela Víťazoslava Hronca realizovanú v širšom kontexte premien európskej literatúry, prostredníctvom ktorej Šimáková Spevákova presvedčivo zdokumentovala svoju základnú výskumnú tézu, podľa ktorej je intertextualita u tohto spisovateľa základným významotvorným činiteľom, ontologickým princípom a estetickou normou.
ПА THE DIALOGUE OF THREE WOMEN ABOUT LOVE: PHAEDRA, MARINA CVETAEVA, SARAH KANE
Authors: АСИМОПУЛОС ПАНАЈОТИС ГЕОРГИОС , Пападопулу Иоана 
Published: October 2018

Uprkos dominantnom mišljenju da je bio žestoki ženomrzac, mudri Euripid se u klasično doba divi Fedrinim vatrenim osećanjima: u tragediji Hipolit Ovenčan (428 p.n.e.) majstorski vodi dramsku junakinju, dok kroz njenu ranjivu psihu prikazuje poguban preobražaj iz nevinog osećaja u autodestruktivnu strast.
Na Fedrinom mitu zasniva se buntovna pokretna sila Marine Cvetajeve u istoimenoj pesmi (1923), gde ruska pesnikinja uspeva da spoji svoja vanbračna traganja sa postizanjem punoće intelektualnog i umetničkog stvaralaštva. Oponašajući tragičan kraj legendarne Fedre, ali i izopštene Cvetajeve, Sara Kejn, kontroverzna autorka pozorišnog dela Fedrina ljubav (1996) vešanjem okončava svoj kratak život. Pri tome, usvajanjem autentičnog Brehtovog stava zadivljuje gledaoce, ne manipuliše njima pasivno, ali napada lažne moralne vrednosti, dok provodi multidimenzionalnu politiku i oštru feminističku kritiku.
Usklađen sa bazičnim načelima intertekstualnog proučavanja i komparativne književnosti ovaj rad pomoću karakterističnih citata osvrće se na specifičnu dijalektičku raspravu dve pesnikinje o Fedrinom liku, dok teži ka ustanovljenju njegove fizionomije i diferencirane percepcije. Razmatranjem drevnogrčke tragedije, Cvetajevine inspiracije i Kejnine pesme, izvodi se zaključak da je ljubavna strast čvrsta podloga jakih sukoba sa opšteprihvaćenom logikom, ali i neiscrpan izvor kreativnosti.
UNDERSTANDING THE THEORY BEHIND LEXICOGRAPHIC PRACTICE: THE CASE OF SYNONYMY
Authors: Halas Ana 
Published: October 2018

This paper analyzes the representation of synonymy within entries in English dictionaries of synonyms and thesauri with the aim of revealing and comparing theoretical views of this phenomenon that these lexicographic resources are based on as well as gaining an insight into the general character of the theoretical foundation of English lexicographic practice related to the treatment of synonymy. The mentioned theoretical views are determined on the basis of two aspects: the scope of the notion of synonymy and the relation between synonymy and polysemy. The results of the analysis have shown that the theoretical foundation of the given practice is two-type taking into account both examined aspects. The analyzed lexicographic resources are based on near-synonymy exhibiting two types – the one with a narrower and the one with a broader scope. Moreover, synonymy and polysemy are viewed in two ways: as independent lexical phenomena or as interrelated phenomena, inseparable from each other.
Key words: synonymy, synonym set, polysemy, English, lexicography, dictionary of synonyms, thesaurus.
ANALISIS PROSES PEMBERDAYAAN PADA PEROKOK DI KAMPUNG BULAKSARI RT 7
Authors: Sadono Delfi Novella 
Published: October 2018

Proporsi penduduk umur 10 tahun keatas yang menjadi perokok aktif sebanyak 23.9% perokok setiap hari dan 5% perokok yang kadang-kadang. Di Surabaya sendiri, sebanyak 13% remajanya adalah perokok aktif. Beberapa contoh yang telah menerapkan tidak merokok di dalam rumah dan lingkungan mereka yaitu salah satunya adalah Kampung Bulaksari RT 7 RW 6, Kelurahan Wonokusumo, Kecamatan Semampir, Surabaya. Kampung Bulaksari RT 7 memiliki jumlah perokok yang lebih tinggi dibandingkan kampung lain yaitu pada awalnya sekitar 67 kepala keluarga yang merokok. Selain itu, Kampung Bulaksari merupakan daerah yang lingkungannya padat dan rumah-rumah yang sangat berdekatan serta daerah yang rawan. Tujuan penelitian ini untuk melakukan analisis proses pemberdayaan pada perokok terutama pada perokok yang telah berhenti di Kampung Tanpa Asap Rokok di Kampung Bulaksari RT 7. Penelitian ini menggunakan pendekatan kualitatif tipe studi kasus. Data studi kasus diperoleh tidak saja dari kasus yang diteliti, namun juga diperoleh dari semua pihak yang mengetahui dan mengenal kasus tersebut dengan baik. Proses pemberdayaan yang telah dilakukan oleh masyarakat melalui tiga tahap yaitu tahap penyadaran, tahap ini masyarakat mengadakan sosialisasi dengan mengundang narasumber dari puskesmas tentang bahaya merokok dan manfaat berhenti merokok. Selanjutnya, tahap pengkapasitasan yaitu upaya berhenti merokok dan upaya tidak merokok dikawasan tanpa rokok dan kawasan terbatas merokok. Selanjutnya tahap pendayaan yaitu terwujudnya Kampung Tanpa Asap Rokok dilingkungan Kampung Bulaksari RT 7 itu sendiri. Kata kunci: pemberdayaan, rokok, kampung tanpa asap rokok, masyarakat kampung
IDENTIFIKASI KEBERADAAN BAKTERI COLIFORM DAN TOTAL MIKROBA DALAM ES DUNG-DUNG DI SEKITAR KAMPUS UNIVERSITAS MUHAMMADIYAH SURAKARTA
Authors: Putri Aprilia Mustikaning , Kurnia Pramudya 
Published: October 2018

Coliform bacteria is microorganisms that can be used as indicator todefine the quality of water. Bacteria in food or drink indicates that the food may be contaminated by stool. The purpose of this research was to describe the total number of microbes and the number of bacteria coliform on “dung-dung” ice around Universitas Muhammadiyah Surakarta campus. This descriptive research used 7 samples which were taken from 7 “dung-dung” ice sellers around Muhammadiyah University of Surakarta. The samples were analyzed by using Total Plate Count (TPC) and Most Probable Number (MPN) methods. The results were compared with standard value of TPC and MPN according to the Indonesia Food and Drug Administration Regulation number 16/2016 about the criteria for food microbiology. The results of the study showed that all of the 7 samples being tested were above the standards, because the microbes count were above 105 CFU/ml (the standard is maximum 104 CFU/ml), and the MPN value > 2400 MPN/ ml (the standard is 10 APM/100ml) This study concluded that all of the “dung-dung” ice studied were not comply the food safety standard.
Variable Laser Wall-plug Efficiency
Authors: Shammi Shamanta 
Published: October 2018

In most studies reported in literature, a flat,
constant coefficient is used to convert the amount of optical power
required at the input of an optical link into the effective power
consumption. This constant coefficient approach is very simple to
apply but not accurate, since laser efficiencies are dependent on
the optical output power in addition to the operating temperature.
In this paper the relationship between laser wall plug efficiency
and optical power output is investigated and the effect of this
variance on optical links and on-chip laser source electric power
consumption is presented
Pelaksanaan Teknik Evaluasi Pembelajaran Sejarah Peradaban Islam di IAIN Sultan Maulana Hasanuddin Banten
Authors: Ratni Ratni , Suriani Suriani 
Published: October 2018

In the greatness time of Islamic Civilazation, Islamic Education chose oral exam for evaluation technic. The result of evaluation on education is for evaluate life with face all the trials, but its a life its self. How about now, what kind of evaluation are use by lecturer and why they choose for the evaluation? The aim of the research is to describing technic evalution for learning Islamic Civilazation History at IAIN Sultan Maulana Hasanuddin Banten in 3 Faculty. The method is Kualitatif Research in case study wich deskriptif analitif Method. The kualitatif was conducted through observation, interview, and documens. The result are two factors influencing lecturer to choose and use evaluation technic (1) the learning purpose and (2) lecturer education background.
Keywords: Evaluation Teknic, Islamic Civilazation History, Lecturer
Abstrak: Di masa kejayaan Peradaban Islam memilih teknik ujian lisan. Hasil dari evaluasi dalam dunia pendidikan merupakan upaya mengevaluasi hidup dalam menghadapi setiap cobaan. Tujuan dari penelitian ini untuk memberikan gambaran pelaksanaan teknik evaluasi pembelajaran Sejarah Peradaban Islam dengan metode deskriptif analitik. Focus penelitian ini adalah untuk melihat dan memaparkan mengapa dosen pengampu pembelajaran Sejarah peradaban Islam menggunakan teknik evaluasi tertentu. Tiga aspek yang dikaji adalah bagaimana perencanaan pembelajaran, proses pembelajaran dan teknik evaluasi dalam ranah kognitif serta afektif. Temuan penelitian ini mendapatkan hasil bahwa faktor-faktor yang mempengaruhi dosen pengampu mata kuliah Sejarah Peradaban Islam memilih dan menggunakan teknik evaluasi ada dua, yaitu: tujuan pembelajaran dan latar belakang pendidikan dosen. Gabungan dari dua faktor temuan itu menghasilkan pola pemilihan dan pelaksanaan teknik evaluasi pembelajaran Sejarah Peradaban Islam.
Kata kunci: Dosen, Sejarah Peradaban Islam, Teknik Evaluasi.