bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Divorce Counseling based on Gottman's Approach on the Self-Efficacy in Divorce Management of Couples Applying for Divorce
Authors: Mahmoodabadi Hassan Zareei , Zarei Fatemeh 
Published: January 2019

Background: Today, couples applying for divorce need more self-efficacy in their divorce management.
Self-efficacy in divorce management helps divorcing couples make the right decision to continue their married life or leave. The present study aimed to determine the effect of divorce counseling based on Gottman's approach on self-efficacy in divorce management within couples who applied for divorce in Yazd.
Methods: This quasi-experimental study was based on pre-test, post-test, and follow-up method in which the case-control group design was applied. The study population included all couples who applied for divorce in Yazd in 2017. We selected 32 participants using purposive sampling, who were then divided into experimental and control groups. In order to collect the study data, we used Zareei's self-efficacy questionnaire in divorce management. To analyze the data, we run multivariate analysis of variance (MANOVA), two-way analysis of variance, and repeated measurement tests.
Results: The results of MANOVA analysis indicated that the experimental group used self-efficacy more frequently than the control group in divorce management and its subscales. Moreover, analysis of two-way variance showed that gender did not have a significant correlation with the training results. In other words, the effect of education was the same for both genders. Moreover, the results of repeated measurement analysis indicated significant differences between the levels (pre test with post test and follow up).
Conclusion: Gottman-based divorce counseling affected self-efficacy in divorce management of couples applying for divorce in Yazd. The effectiveness of this training was the same for both males and females. As a result, for those couples who want to divorce, such training seems to be extremely necessary.

Keywords: Divorce Counseling, Tendency to Divorce, Divorce Management, Gottman, Self-Efficacy
A Content Analysis of the Research Articles Written on online-counseling
Authors: Ceker Eser 
Published: January 2019

The aim of this study was to examine the research studies conducted between 2000-2017 about â€œonline counselingâ€ with particular attention to the publication year, number of researcher in the researching teams, country of the researching university/researcher, application area researched, publication source, author, affiliation, research document type, and the research model used. According to the results; teams composing from two to three researchers are more common than studies researched by a single person. Applications focusing on â€œAnalyzing Online Counselingâ€ and â€œOnline Counseling for Health & Medicineâ€ are most preferred researched areas. Results also indicate that, more researchers from USA and Australian Universities studied â€œonline counselingâ€ related problems than others. The total number of research carried out for online counseling seems to have increased from 2007 onwards. It is believed that, these results together with the recommendations and comments may be supportive and helpful especially for the future online counseling research studies in developing countries.
Relationship of Traffic Noise with High Blood Pressure to Pedicab Drivers Around Purabaya Bus Station Surabaya
Authors: Addina Shita , Keman Soedjajadi 
Published: January 2019

Abstract: The existence of bus station can make some problems, one of which is the traffic noise. Traffic noise can induce an increased blood pressure. Therefore, the purpose of this study was to analyzed the relationship between level of traffic noise and increased blood pressure in pedicab drivers around Purabaya bus station. The study was carried out using by cross sectional method. Measurement of traffic noise was carried out around Purabaya bus station Surabaya with Sound Level Meter. Measurement of blood pressure with sphygmomanometer. Sampling method used by simple random sampling with 22 respondents respectively and then total of respondents are 44 respondents. The result of study indicated there was a relationship between the level traffic noise with increased blood pressure (hypertension) (p = 0.034). Another factor related to blood pressure was descendants of the family history (p = 0.002). It was concluded that traffic noise related with increased blood pressure in pedicab drivers. Suggested for the next researcher doing the measurement noise more than a day to get the actual average noise level. In addition, other factors related to the blood pressure should examined to get main factor of hypertension.Keywords: traffic noise, blood pressure, pedicab drivers
Relations of existential characteristics and hardiness with psychosomatic cardiac symptoms in young people
Authors: Grigoriev P. E. , Vasilieva I. V. 
Published: January 2019

Objective. Evaluation of the psychological well-being and hardiness in adolescents with cardiac symptoms.Materials and methods.The study involved 80 people aged 18–24 years, a relatively healthy sample. To assess the existential characteristics, the scale of psychological well-being of С. Ryff in the adaptation of N.N. Lepeshinsky. To assess the psychological quality of hardiness, the S. Maddi questionnaire was used in adaptation D.A. Leontiev, E.I. Rasskazova. To assess the psychosomatic component of cardiac symptoms the Giessen questionnaire of psychosomatic complaints was used. Descriptive statistics methods, the Mann – Whitney test for independent samples, a one-way analysis of variance with a posteriori pairwise comparison using the Newman-Keuls test were used.Results.For members of the healthy sample at the age of 18–24 years, the severity of psychosomatic cardiac complaints is relatively homogeneous by sex and age; the most significant differences in existential characteristics and hardiness in connection with the severity of psychosomatic cardiac symptoms fall on indicators of “commitment”, “control”, “environmental management”. Conclusion. The most significant and discriminating contribution to the prevention of psychosomatic cardiac complaints is such existential and stress-coping characteristics of personality as the ability to effectively use life situations to achieve one’s own goals, to fight for success and get results from their actions, to strive for maximum involvement in the activities of interest for the reflected, conscious meaning in life.
Clinical description of affective disorders and efficiency of antidepressant therapy
Authors: Lebedeva E. V. , Schastnyy E. D. , Simutkin G. G. , Repin A. N. , Nonka T. G. 
Published: January 2019

Objective:to identify the structure and clinical features of affective disorders (AD) and efficiency of antidepressants in in-patients with chronic coronary artery disease (ChCAD), living in Tomsk and the Tomsk Region.Materials andмethods.At a heart center, 1,131 patients with ChCAD were examined: in 290 persons (25.6%) AD were revealed, among them 72.1% were men (n= 209) and 27.9% were women (n= 81). Mean age of women was (63.5 ± 9.4) years and in men (57.9 ± 7.2) years (р= 0.004). AD structure, main syndromes, severity of depression and anxiety according to data of self-questionnaires and clinical scales before and after antidepressant therapy (predominantly with selective serotonin reuptake inhibitors (SSRI)) were studied. Comparative analysis of clinical indices of CAD respective from AD, presence of antidepressant therapy and its efficiency was performed.Results.Chronic AD were found in 45% of patients. Newly diagnosed depressive episodes made up 24.5% and recurrent depressive disorder (RDD) was 24%. 6.5% were bipolar affective disorders (BAD), predominantly bipolar II disorders. Depressive syndrome in 91.7% of patients had the second significant component (more frequently 54.8%). Characteristic of the clinical picture was dominance of complaints of bodily discomfort and pain, anergy and anhedonia. Moderate mental disturbances made up 49.0% (CGI). AD manifested at the age of 48 (40–55) years and preceded development of ChCAD. Natural course of AD was observed in 52.4% of cases. 47.6% (138/290) of patients received antidepressants, and only in 42% (58/138) clinically significant improvement was noted (more than 50% according to CGI). It was difficult to encourage patient adherence to long-term therapy (30–50% according to CGI). Physical activity tolerance (PAT) according to data of veloergometry increased in responders. Psychopharmaco- and psychotherapy should be included into rehabilitative programs for patients with ChCAD and AD.
Assessment of in Vitro Comparative Dissolution Kinetics of Moxonidine Products as a Factor Potentially Determining Effectiveness of Antihypertensive Treatment
Authors: Ramenskaya G. V. , Shokhin I. E. , Gaponova N. I. , Abdrakhmanov V. R. 
Published: January 2019

Aim. Investigation of comparative dissolution kinetics of generic medicinal products containing moxonidine versus reference drug. Material and methods. Objects of the research were film-coated tablets containing moxonidine (INN) in a dose 0.4 mg: a reference drug Physiotens® and 4 generic drugs. In vitro dissolution test of moxonidine from the study drugs was performed using comparative dissolution kinetics test (CDKT). The CDKT was performed in the media with the following pH: 1.2 (1:9 mixture of 0.1 M hydrochloric acid and water), 4.5 (acetate buffer solution, prepared as per State Pharmacopoeia, XIII), and 6.8 (phosphate buffer solution, prepared as per State Pharmacopoeia, XIII). The sampling for dissolved moxonidine was performed 5, 10, 15, 20, and 30 min after the test was started. An high performance liquid chromatography method with ultraviolet detection at 220 nm was used to assay. Results. Within 15 min more that 85% of moxonidine dissolved from the reference drug and all study drugs at pH 1.2; dissolution profiles were similar without calculation of similarity factor f2. Similarly, at pH 4.5 dissolution profiles of study drugs #2 and #3 were similar to that of the reference drug, and the similarity factor f2 was not calculated. However, in case of study drugs #1 and #4 significant differences were observed at a single time point (15 min), which suggests that their dissolution profiles are non-similar to that of the reference drug. Similarity factors f2 were calculated 17.52 and 35.30, respectively (less than 50). At pH 6.8 similarity factors f2 for all study generic drugs were also less than 50 (23.8, 49.8, 38.6, and 35.9), so their dissolution curves were non-similar to that of reference drug. Conclusion. In our study we observed difference in release in vitro of medicinal products containing moxonidines: none of the study drugs was fully similar to the reference drug in all media. The differences observed at pH 6.8 were noteworthy, where the samples had or faster kinetics (study drugs #2 and #3), or slower dissolution kinetics (test drugs #1 and #4). Observed differences in moxonidine release rate may impact absorption of active pharmaceutical ingredient into the blood following drug administration.
A Double-blind Randomized Comparative Clinical Trial to Evaluate the Safety and Efficacy of Dendritic Cell Vaccine Loaded with WT1 Peptides (TLP0-001) in Combination with S-1 in Patients with Advanced Pancreatic Cancer Refractory to Standard Chemotherapy
Authors: Katsuda Masahiro , Miyazawa Motoki , Ojima Toshiyasu , Katanuma Akio , Hakamada Kenichi , Sudo Kentaro , Asahara Shingo , Endo Itaru , Ueno Makoto , Hara Kazuo , Yamada Suguru , Fujii Tsutomu , Satoi Sohei , Ioka Tatsuya , Ohira Masaichi , Akahori Takahiro , Kitano Masayuki , Nagano Hiroaki , Furukawa Masayuki , Adachi Tomohiko , Yamaue Hiroki 
Published: January 2019

Abstract
Background: Pancreatic cancer is a refractory malignancy and the development of a new effective treatment strategy is needed. We generated a dendritic cell vaccine by culturing monocytes obtained by apheresis of blood from each patient, inducing their differentiation into dendritic cells, and pulsing with tumor antigen peptides. However, the clinical efficacy of the vaccine has not been established. We therefore decided to conduct an exploratory clinical trial of dendritic cell vaccine loaded with Wilms’ tumor gene 1 peptides (TLP0-001) as a potential new treatment for patients with advanced pancreatic cancer refractory to standard chemotherapy.
Methods: This is an investigator-initiated double-blind comparative trial. The patients were allocated to two groups in a 1:1 ratio through a central registration by dynamic allocation. A total of 185 patients with inoperable or metastatic pancreatic cancer who were refractory or intolerant to standard primary chemotherapy with gemcitabine plus nab-paclitaxel will be allocated to secondary treatment either with placebo in combination with S-1 (the control group) or TLP0-001 in combination with S-1 (the investigational product group). The primary objective of this trial is to evaluate the safety and efficacy (as measured by overall survival) of the investigational product by comparing the two groups. This clinical trial will be performed in accordance with Japanese Good Clinical Practice guidelines.
Discussion: Clinical trials of the standard regimen, including gemcitabine, for advanced pancreatic cancer are ongoing worldwide. However, a strategy for after the primary treatment has not been established. We therefore decided to conduct this study to evaluate the safety and efficacy of TLP0-001 as a secondary treatment for pancreatic cancer in anticipation of the approval of this new drug in Japan. This trial is conducted with full consideration of safety as it is the first-in-human clinical trial of TLP0-001; thus, the trial will be conducted only at the Second Department of Surgery at Wakayama Medical University until the safety is confirmed by interim analysis. We plan to conduct a multicenter trial at 18 institutions in Japan after confirmation of the safety.
Ultrasound-guided deep nerve block may increase the rate of local anesthetics toxicity in HBV carriers: A Randomized clinical trial
Authors: Zhang Xu-hao , Li Yu-jie , He Wenquan , Yang Chunyong , Gu Jianteng , Lu Kaizhi , Yi Bin 
Published: January 2019

Abstract
Background: Ultrasound-guidance might decrease the incidence of local anesthetics systemic toxicity(LAST) for many peripheral nerve blocks compared to nerve stimulation. However, it remained uncertain whether ultrasound-guidance would be superior to the nerve stimulation for deep nerve block in the lower extremity. This study was designed to investigate that deep nerve block with ultrasound-guidance would result in a lower rate of LAST comparing to that with nerve stimulator-guidance.
Methods: Three hundred patients who were for elective lower limb surgery and desiring lumbar plexus blocks(LPBs) and sciatic nerve blocks(SNBs) were enrolled in this study. Patients were randomly assigned to receive LPB and SNB with ultrasound-guidance (Group U), nerve stimulator-guidance (Group N) and dual-guidance (Group M). The primary outcome was the incidence of the LAST. The secondary outcomes were number of needle redirections, motor and sensory block onset and restoration times in the nerve distributions, and associated risk factors.
Results: There were 18 patients with the LAST, including 12 in group U, 4 in group N and 2 in group M. For multiple comparisons among the tree groups, we found that the incidence of LAST in group U(12%) was significantly higher than that in group N(4%)(P=0.037) and group M(2%)(P=0.006). The OR of LAST with HBV infection and female gender was 3.352(95% CI,1.233-9.108, P=0.013 ) and 9.488(95% CI,2.142-42.093, P=0.0004), respectively.
Conclusions: For patients undergoing LPBs and SNBs, use of ultrasound may increase the incidence of the LAST. HBV infection and female gender were risk factors for deep nerve block.
Trial registration: This study was approved by the human research review committee at the southwest hospital of third military medical university. The protocol was registered prospectively with Chinese Clinical Trial Registry (ChiCTR-IOR-16008099) on March 15th，2016.
Keywords: Ultrasound; nerve stimulation; nerve block; female; HBV; LAST
The Relationship Between Perceived Social Support in Pregnancy and Self-Efficacy for Childbirth Fear - A Cross-Sectional Study in Arak City, 2017
Authors: Vakilian Katayon , Zarin Fatemeh , Zaraj Hoda 
Published: January 2019

Background:
It seems that with perceived social support, self-efficacy for childbirth fear can be strengthened in pregnant women. The present study aimed to investigate the relationship between perceived social support in pregnancy and self-efficacy for childbirth fear in Arak.

Methods:
This cross-sectional study was conducted on 180 pregnant women. Sampling was done on convenience and health centers were selected randomly. After receiving written consent, the standard questionnaire of perceived social support and the self-efficacy for childbirth fear was given to pregnant women. The questionnaires were collected immediately after completion. After collecting the data, the information was entered into the spss18 software and the Pearson test was used for data analysis.

Results:
The mean score of self-efficacy for childbirth fear, and perceived social support were 34.55±8.183, 23.93±11.047 respectively. Also, there was no correlation between self-efficacy for childbirth fear and family, friends, and others perceived social support (p >0.05).

Conclusion:

From the results it seems that the subjective evaluation of the individual from her supporters during pregnancy is not effective on self-efficacy for childbirth fear which is subjective as well. Therefore, health providers should involve directly the husband and the wife’s family regarding supporting the pregnant woman during prenatal care.
Health-Related Quality of Life and Associated Factors Among People Living with HIV /AIDS Following ART Clinic in Jimma University Specialized Hospital, Southwest Ethiopia: A Facility- Based Cross-Sectional Study
Authors: Tesfaye Tamiru , Darega Jiregna , Belachew Tefera , Abera Abebe 
Published: January 2019

Background:HIV care of people living with HIV /AIDS (PLWH/A) is critical for fruitful HIV inhibition, treatment and provision of quality of life. The goal of Anti-Retroviral Therapy (ART) is to suppress viral replication, lessen morbidity and death, and improve patients’ quality of life. The quality of life of HIV/AIDS patients is not well appraised in the study area beforehand. Therefore, this study assessed the health-related quality of life and associated factors among people living with HIV /AIDS followed by ART Clinic in Jimma University Specialized Hospital, Southwest Ethiopia.Methods:We used facility based cross-sectional study design and 351 samples selected by systematic random sampling from Jimma University Specialized Hospital ART clinic in March-2014. Data were collected through interviewer-administered questionnaires and analyzed by using SPSS version 20.0 software. Descriptive analysis (frequency and percentage) was calculated. Bivariate and multivariate analyses were used to identify associated factors. The association between the explanatory and dependent variables was assessed at p-value of less than 0.05. The results were presented in a narrative form, tables and graphs.Results:From the total respondents, 143 (40.7%) of them have low quality of life in general. Of these, 238 (67.8%) of them had low psychological domain, 136 (38.7%) had low physical domain and 223 (63.5%) low social domain. The age ≤ 39 years (AOR = 2.381 [95% CI = 1.238, 4.579]), Currently employed (AOR= 3.509 [95% CI = 1.900, 6.482]), current CD4 count ≥ 250 cell/ml (AOR = 2.663 [95% CI = 1.363,5.203]), current WHO Stage I-II (AOR = 4.772 [95% CI = 2.308, 9.865]), good general health condition (AOR = 2.609 [95%CI = 1.372, 4.961]), no comorbidity (AOR = 7.737 [95% CI = 4.146, 4.438), friendly social relationship (AOR = 5.395 [95% CI = 2.781, 10.467]), other persons reminded their drugs took time (AOR = 3.363 [95% CI = 1.629, 6.943]) and drunk alcohol (AOR = 1.915[95% CI = 1.039, 3.529]) were identified as the predictors of health related quality of life.Conclusion:Findings of this study indicate that the significant number of participants exists on low-level- of health related quality of life in general. The age, occupation, current CD4 count level, current WHO stage status, general health conditions, comorbidity conditions, status of their social relations, their conditions due to lack of support, reminder of drugs taking time, and alcohol drinking status have been observed to have a statistically significant association with their health-related quality of life status.
Around 1000 BC. Absolute dates for the Final Bronze Age – Early Iron Age transition in Italy: wiggle-match 14C dating of two tree-trunk coffins from Celano
Authors: Plicht J. Van der , Nijboer A.J. 
Published: January 2019

At Celano (Abruzzo region, Italy), rare tumulus tombs of the Final Bronze Age were excavated, yielding waterlogged coffins of oak wood. Two tombs were dated by Wiggle-Match Dating (WMD), using the conventional 14C method. This shows that the tumuli were erected around 1030 BC, while the associated artefacts in the sarcophagi are attributable to the final stages of the Bronze Age (FBA) in Italy. Fibulae similar to those found in both tombs at Celano are recovered in modest numbers all over the Italian peninsula and even in Croatia and nearby regions (Glogović 2003; von Merhart 1969, pls. 4, 5, 7). Our date of ca. 1030 BC for the last stages of the Bronze Age in Italy has consequences for the beginning of the Iron Age, which should start around 1000-950 BC, an assessment that is consistent with other radiocarbon sequences obtained for Italy, such as the sequence for Latium Vetus and elsewhere in the western Mediterranean.