bluuebunny/crossref_metadata_2025_split huggingface dataset:
A review of vertical evacuation on tsunami mitigation case
Authors: Haiqal M , Sari L H , Evalina Z , Hasibuan P 
Published: July 2019

Abstract
Banda Aceh City was hit by a tsunami at the end of 2004. The experience of this great disaster directly or indirectly has led to many problems that are a must in finding the right solution. It is very important to do in order to minimize the disaster victims of the tsunami in the future. During the rehabilitation and reconstruction period after the 2004 earthquake and tsunami, between 2005 until now, various mitigation efforts have been carried out. One of the tsunami mitigation efforts is to build tsunami evacuation buildings. The city of Banda Aceh is one of the cities in Indonesia that has vertical tsunami evacuation facilities such as escape building. Although it still does not meet the expected availability standards, it can be called the right initial step for Banda Aceh City in the face of the tsunami disaster in the future. However, its existence will be in vain if the community does not use it to its full potential in their daily activities. This study evaluates the effectiveness of the escape building for vertical evacuation based on some supporting literature reviews.
Optimal conditions for selective reduction process of Nickel Laterite Ore
Authors: Nurjaman F , Sa’adah A , Suharno B 
Published: July 2019

Abstract
A low-grade nickel laterite ore from Indonesia was selected to investigate the effect of temperature and time of reduction upon the extraction of nickel through the selective reduction-magnetic separation process to produce the ferronickel. The nickel ore was mixed with5 wt.% of anthracite coal and 10 wt.% of sodium sulfate additive. The mixed ore was pelletized into 10-15 mm of diameter. A series of selective reduction processes were carried out into the pellet ores at various temperatures of 950-1150 °C for 60-120 minutes. The optimal selective reduction parameters of nickel laterite ore were observed clearly. The experimental results indicated that the reduction reactions proceed more completely at a higher temperature and longer reduction time. The optimum of nickel grade and recovery in the ferronickel concentrate was obtained at the reduction temperature of 1150 °C for 120 minutes, which was 8.45% and 72.1%, respectively. The increasing of temperatures and times of reduction process resulted in higher of troilite phase formation which suppressed the iron metallization and also increased the ferronickel particle size.
Mechanical behavior of hybrid glass Fiber-Jute reinforced with polymer composite for the wall of the Acehnese boat ‘Jalo Kayoh’
Authors: Akram A , Hasanuddin I , Nazaruddin N , Putra R , Noor MM 
Published: July 2019

Abstract
Hybrid fiber composites are widely used composites in engineering applications, especially for the frame and wall structure of Acehnese traditional boat Jalo Kayoh. The purpose of this study is to obtain a hybrid material which is a blend of natural jute fiber reinforced with the synthetic fibers E-glass and polyester as a matrix. The materials potential to become a material for the structure and walls in the traditional Acehnese boat Jalo Kayoh. The fabrication of the hybrid composites is carried out manually using an engineered press at a pressure of 25 kg/cm2 for 24 hours. The ratio of jute fiber and E-glass in the composites at each layer are (1:0), (1:1) and (2:1). Tensile testing of the hybrid composites refers to ASTM D 3039 - 00. The results show that the tensile strength of the hybrid composites tends to increase with the increase in the volume of the fiber, with the maximum tensile strength of 4.8 MPa. The increasing number of layers in the jute and E-glass is adding strength to the composites. This will be good to use in the initial material of the structure and walls in the traditional Acehnese boat Jalo Kayoh.
Mechanical properties of glass fiber reinforced polyester resin for use as the wall of the Acehnese boat ‘Thep-Thep’
Authors: Nazaruddin N , Akram A , Hasanuddin I , Iqbal M , Kurniawan R , Putra R 
Published: July 2019

Abstract
Fiber composites are very commonly used for engineering applications nowadays. The product has begun to enter the field of boat and ship manufacturing. An Acehnese traditional boat known as thep-thep, which has a capacity of 3 GT, is a means of transportation used in Aceh waters. This study focuses on the mechanical properties of the material used for the structure and walls of the thep-thep. Specimens are made from materials with E-glass fiber reinforced polyester resin. The hand lay-up method is used in the process of making the specimens, applied with a pressure of 25 kg/cm2 for 24 hours. This study aimed to obtain higher mechanical properties using composites of layers of chopped strand mat (CSM) fibers and woven roving mat (WRM) fibers with a ratio of 1:0, 1:1, and 2:1, respectively. Tensile testing is done using the ASTM D3039-00 standard. From the tensile test data obtained from several different composite ratios, the highest composite is found at around 49.2 MPa. An increase in the number of fiber layers makes the fiber composites more reliable to be the raw material in the making of the Acehnese boat thep-thep.
Study of temperature loss of Hot Mix Asphalt during transportation
Authors: Muhammad  , Syuhada A , Huzni S , Fuadi Z 
Published: July 2019

Abstract
This study was conducted to observe the phenomenon of the temperature loss on hot mix asphalt type Asphalt Concrete Binder Course (AC-BC), on the surface area of the truck wall during transport. The tests were conducted experimentally using thermometers and thermocouples with a 25-ton capacity truck at 153°C loading temperatures. Data retrieval is carried out over time, 20.40,60 to 420 minutes of transport, from the Asphalt Mixing Plant (AMP) plant to the job site with an average truck speed of 30 km/h. Data from the results of the study were analyzed using the descriptive method. The results indicate that the maximum transport distance that meets the technical specifications is at the furthest distance of 165 km, with a minimum temperature of 130,1°C, at a distance of 10 cm from the surface of the truck wall. Loss of average hot mix asphalt temperature to 6 (six) sides of the truck wall surface, floor surface and the top surface, for 420 minutes of transport is (45.2°C-65.7°C). From the phenomenon shows that the hot mix asphalt condition on the surface area of the truck wall is hardened (crusty).
The Great Bee Migration: Supply Analysis of Honey Bee Colony Shipments into California for Almond Pollination Services
Authors: Goodrich Brittney K. , Williams Jeffrey C. , Goodhue Rachael E. 
Published: July 2019

AbstractOver the last two decades, the number of honey bee colonies performing pollination services for the California almond industry has grown steadily and now equals a substantial share of all colonies in the United States. Most US beekeeping operations have not expanded their colony numbers at the current levels of almond pollination fees. Thus, as almond acreage has increased, the marginal supplier of colonies has moved further away from California, increasing interstate shipments. We provide a conceptual representation of the supply and demand of U.S. colonies for almond pollination, and utilize the relatively inelastic demand for colonies to explore spatial elasticities of supply. We combine colony shipment data from 2007 to 2018 provided by the California Department of Food and Agriculture with projected prices from the California State Beekeeper's Association pollination fee survey. We use a geographically weighted regression to estimate supply elasticities for each state, and provide supporting regional estimates. The eastern United States, where beekeepers have hesitated to participate in almond pollination due to relatively high transportation costs and the potential for local honey production at the time of almond bloom, have some of the highest price elasticities of supply. This suggests that beekeepers in areas with low transportation and/or opportunity costs have supplied all available colonies, and increases in almond pollination fees have had little effect. We estimate that Florida, Georgia, and Texas had the largest number of colonies that did not participate in almond pollination in 2017, so further increases in supply are likely to come from those states.
Defining Death-Eligible Murder in China
Authors: Miao Michelle 
Published: July 2019

Abstract
The central purpose of this Article is to illuminate the process and politics of China’s sentencing regime for capital murder. Since 2007, China’s death penalty reform has resulted in a recalibration of the convicted murderer’s eligibility for execution. The reform heralded a substantial decline in the number of capital sentences, as well as a rise of an alternative to execution: the suspended death sentence. In the reform era, how do Chinese courts determine who should be spared from execution and who deserves the ultimate punishment of death? This Article uses a quantitative analysis of 369 capital murder cases, as well as elite interviews with forty judges—from China’s provincial-level Higher People’s Courts and the Supreme People’s Court—to analyze the political logic behind Chinese courts’ approach to defining the execution worthiness of convicted murderers. While there is a rich literature on capital sentencing in the United States, there is a dearth of comparative analysis of the challenges Chinese courts face in drawing the distinction between life and death sentences in the country’s unique social and political context. This Article seeks to make a contribution to this crucial topic.
HDX-Viewer: interactive 3D visualization of hydrogen–deuterium exchange data
Authors: Bouyssié David , Lesne Jean , Locard-Paulet Marie , Albigot Renaud , Burlet-Schiltz Odile , Marcoux Julien 
Published: July 2019

AbstractSummaryWith the advent of fully automated sample preparation robots for Hydrogen–Deuterium eXchange coupled to Mass Spectrometry (HDX-MS), this method has become paramount for ligand binding or epitope mapping screening, both in academic research and biopharmaceutical industries. However, bridging the gap between commercial HDX-MS software (for raw data interpretation) and molecular viewers (to map experiment results onto a 3D structure for biological interpretation) remains laborious and requires simple but sometimes limiting coding skills. We solved this bottleneck by developing HDX-Viewer, an open-source web-based application that facilitates and quickens HDX-MS data analysis. This user-friendly application automatically incorporates HDX-MS data from a custom template or commercial HDX-MS software in PDB files, and uploads them to an online 3D molecular viewer, thereby facilitating their visualization and biological interpretation.Availability and implementationThe HDX-Viewer web application is released under the CeCILL (http://www.cecill.info) and GNU LGPL licenses and can be found at https://masstools.ipbs.fr/hdx-viewer. The source code is available at https://github.com/david-bouyssie/hdx-viewer.
Chikungunya, a Risk Factor for Guillain-Barré Syndrome
Authors: Stegmann-Planchard Sophie , Gallian Pierre , Tressières Benoit , Leparc-Goffart Isabelle , Lannuzel Annie , Signaté Aissatou , Laouénan Cédric , Cabié André , Hoen Bruno 
Published: July 2019

Abstract
In a matched case-control study where 24 cases developed Guillain-Barré syndrome (GBS) during the 2014 chikungunya outbreak in the French West Indies and 72 controls were blood donors during the same period, chikungunya infection was a risk factor for GBS (odds ratio, 8.3; 95% confidence interval, 2.3–29.7; P = .001).
Predictors of Clostridioides difficile Infection Among Asymptomatic, Colonized Patients: A Retrospective Cohort Study
Authors: Poirier Dominic , Gervais Philippe , Fuchs Margit , Roussy Jean-Francois , Paquet-Bolduc Bianka , Trottier Sylvie , Longtin Jean , Loo Vivian G , Longtin Yves 
Published: July 2019

Abstract

Background
Asymptomatic patients colonized with Clostridioides difficile are at risk of developing C. difficile infection (CDI), but the factors associated with disease onset are poorly understood. Our aims were to identify predictors of hospital-onset CDI (HO-CDI) among colonized patients and to explore the potential benefits of primary prophylaxis to prevent CDI.

Methods
We conducted a retrospective cohort study in a tertiary academic institution. Colonized patients were identified by detecting the tcdB gene by polymerase chain reaction on a rectal swab. Univariate and multivariate logistic regression analyses were used to identify predictors of HO-CDI.

Results
There were 19 112 patients screened, from which 960 (5%) colonized patients were identified: 513 met the inclusion criteria. Overall, 39 (7.6%) developed a HO-CDI, with a 30-day attributable mortality of 15%. An increasing length of stay (adjusted odds ratio [aOR] per day, 1.03; P = .006), exposure to multiple classes of antibiotics (aOR per class, 1.45; P = .02), use of opioids (aOR, 2.78; P = .007), and cirrhosis (aOR 5.49; P = .008) were independently associated with increased risks of HO-CDI, whereas the use of laxatives was associated with a lower risk of CDI (aOR 0.36; P = .01). Among the antimicrobials, B-lactam with B-lactamase inhibitors (OR 3.65; P &lt; .001), first-generation cephalosporins (OR 2.38; P = .03), and carbapenems (OR 2.44; P = .03) correlated with the greatest risk of HO-CDI. By contrast, patient age, the use of proton pump inhibitors, and the use of primary prophylaxis were not significant predictors of HO-CDI.

Conclusions
This study identifies several factors that are associated with CDI among colonized patients. Whether modifying these variables could decrease the risk of CDI should be investigated.
Physiological and transcriptional comparison of acetate catabolism between Acinetobacter schindleri ACE and Escherichia coli JM101
Authors: Sigala Juan-Carlos , Quiroz Lucy , Arteaga Eduardo , Olivares Roberto , Lara Alvaro R , Martinez Alfredo 
Published: July 2019

ABSTRACT
Acinetobacter bacteria preferentially use gluconeogenic substrates instead of hexoses or pentoses. Accordingly, Acinetobacter schindleri ACE reaches a high growth rate on acetate but is unable to grow on glucose, xylose or arabinose. In this work, we compared the physiology of A. schindleri ACE and Escherichia coli JM101 growing on acetate as the carbon source. In contrast to JM101, ACE grew on acetate threefold faster, had a twofold higher biomass yield, and a 45% higher specific acetate consumption rate. Transcriptional analysis revealed that genes like ackA, pta, aceA, glcB, fumA, tktA and talA were overexpressed while acsA, sfcA, ppc and rpiA were underexpressed in ACE relative to JM101. This transcriptional profile together with carbon flux balance analysis indicated that ACE forms acetyl-CoA preferentially by the AckA-Pta (acetate kinase-phosphotransacetylase) pathway instead of Acs (acetyl-CoA synthetase) and that the glyoxylate shunt and tricarboxylic acid cycle are more active in ACE than in JM101. Moreover, in ACE, ribose 5-phosphate and erythrose 4-phosphate are formed from trioses, and NADPH is mainly produced by isocitrate dehydrogenase. This knowledge will contribute to an understanding of the carbon metabolism of Acinetobacter species of medical, biotechnological and microbiological relevance.
Epidemiology and risk factors for carbapenem-resistant Enterobacteriaceae colonisation and infections: case-controlled study from an academic medical center in a southern area of China
Authors: Fang Lili , Lu Xiaohui , Xu Heping , Ma Xiaobo , Chen Yilan , Liu Yue , Hong Guolin , Liang Xianming 
Published: July 2019

ABSTRACT

OBJECTIVE
While the emergence and spread of carbapenem-resistant Enterobacteriaceae (CRE) and related infections pose serious threats to global public health, the epidemiology and associated risk factors remain poorly understood and vary by geography.

METHODS
In a case-controlled retrospective study, we examined the prevalence, patient background and risk factors for CRE colonisation and infections, and all patient-derived CRE from January 2015 to January 2017. Isolated carbapenem-susceptible Enterobacteriaceae (CSE) from 2875 enrolled patients were randomly selected during the study.

RESULTS
CRE colonisation and infections detection rates were 47/2875 (1.6%). Respiratory tract specimens were most frequently seen in 20/47 (42.6%) cases. Klebsiella pneumoniae was the main isolate in 35/47 (74.5%) CRE. As for carbapenemase, KPC-2-producing bacteria was most frequently detected in 38/47 (80.9%) Enterobacteriaceae. No underlying conditions (P = 0.004), pulmonary diseases (P = 0.018) and no antibiotics used prior to culture within 30 days (P &lt; 0.001) were statistically significant between the CRE and CSE groups.

CONCLUSION
Klebsiellapneumoniae was the main isolate of CRE. The blaKPC-2 was the predominant CRE gene. Underlying conditions especially pulmonary diseases and antibiotics used prior to culture within 30 days represented key risk factors for acquisition of CRE.
Established PABPN1 intranuclear inclusions in OPMD muscle can be efficiently reversed by AAV-mediated knockdown and replacement of mutant expanded PABPN1
Authors: Malerba Alberto , Klein Pierre , Lu-Nguyen Ngoc , Cappellari Ornella , Strings-Ufombah Vanessa , Harbaran Sonal , Roelvink Peter , Suhy David , Trollet Capucine , Dickson George 
Published: July 2019

AbstractOculopharyngeal muscular dystrophy (OPMD) is a rare autosomal dominant late-onset muscular dystrophy affecting approximately 1:100 000 individuals in Europe. OPMD is mainly characterized by progressive eyelid drooping (ptosis) and dysphagia although muscles of the limbs can also be affected late in life. This muscle disease is due to a trinucleotide repeat expansion in the polyA-binding protein nuclear-1 gene. Patients express a protein with an 11–18 alanine tract that is misfolded and prone to form intranuclear inclusions, which are the hallmark of the disease. Other features of OPMD include muscle fibrosis and atrophy in affected muscles. Currently, no pharmacological treatments are available, and OPMD patients can only be referred to surgeons for cricopharyngeal myotomy or corrective surgery of extraocular muscles to ease ptosis. We recently tested a two-AAV `silence’ and `replace’ vector-based gene therapy treatment in a mouse model of OPMD. We demonstrate here that this gene therapy approach can revert already established insoluble aggregates and partially rescues the muscle from atrophy, which are both crucially important since in most cases OPMD patients already have an established disease when diagnosed. This strategy also prevents the formation of muscle fibrosis and stabilizes the muscle strength to the level of healthy muscles. Furthermore, we show here that similar results can be obtained using a single AAV vector incorporating both the `silence’ and `replace’ cassettes. These results further support the application of a gene therapy approach as a novel treatment for OPMD in humans.
Patterns of aortic remodelling after total arch replacement with frozen elephant trunk for acute aortic dissection
Authors: Iida Yasunori , Fujii Susumu , Shimizu Hideyuki , Sawa Shigeharu 
Published: July 2019

Abstract

OBJECTIVES
We investigated the outcomes of total arch replacement with frozen elephant trunk (FET) for Stanford type A acute aortic dissection and the patterns of postoperative aortic remodelling from computed tomographic (CT) findings.

METHODS
From April 2015 to November 2018, we performed total arch replacement with FET for Stanford type A aortic dissection in 30 patients. Postoperative contrast-enhanced CT showed the position of the FET distal end, the number and the site of communications between the lumina and the presence or absence of aortic remodelling.

RESULTS
Primary entry tear was found in the ascending aorta (n = 6), proximal arch (n = 6), aortic arch (n = 11) and distal arch (n = 7). The mean diameter and length of FET were 26 ± 2 and 84 ± 18 mm, respectively. Postoperative contrast-enhanced CT was performed in 26 patients. When the number of communications between the lumina was 0, complete aortic remodelling was achieved in all cases (n = 12). In the case of the most proximal tear in the descending aorta (n = 9), aortic remodelling was not recognized in 3 cases, and additional TEVAR was performed because of diameter enlargement. In the remaining 6 patients, neither aortic remodelling nor aortic diameter enlargement was recognized. When the most proximal tear was below the diaphragm (n = 5), aortic remodelling occurred up to the most proximal tear, but not in the periphery.

CONCLUSIONS
We investigated the patterns of aortic remodelling after total arch replacement with FET for Stanford type A aortic dissection from postoperative CT findings. Regardless of the position of the most proximal tear in the descending aorta, aortic remodelling did not occur as long as the most proximal tear was located in the descending aorta. When the most proximal tear occurred in the descending aorta, TEVAR as a pre-emptive treatment can be effective in preventing postoperative aortic adverse events.
Ischaemic heart disease and stroke mortality by specific coal type among non-smoking women with substantial indoor air pollution exposure in China
Authors: Bassig Bryan A , Dean Hosgood H , Shu Xiao-Ou , Vermeulen Roel , Chen Bingshu E , Katki Hormuzd A , Seow Wei Jie , Hu Wei , Portengen Lützen , Ji Bu-Tian , Wong Jason Y Y , Ning Bofu , Downward George S , Li Jihua , Yang Kaiyun , Yang Gong , Gao Yu-Tang , Xiang Yong-Bing , Nagaradona Teja , Zheng Wei , Silverman Debra T , Huang Yunchao , Lan Qing 
Published: July 2019

Abstract

Background
Lifetime use of bituminous (‘smoky’) coal is associated with nearly a 100-fold higher risk of lung cancer mortality compared with anthracite (‘smokeless’) coal use in rural Xuanwei, China, among women. Risk of mortality from ischaemic heart disease (IHD) and stroke for these coal types has not been evaluated.

Methods
A cohort of 16 323 non-smoking women in Xuanwei, who were lifetime users of either smoky or smokeless coal, were followed up from 1976 to 2011. We estimated hazard ratios (HRs) and 95% confidence intervals (CI) to evaluate lifetime use of coal types and stoves in the home in relation to risk of IHD and stroke mortality.

Results
Among lifetime users of smokeless coal, higher average exposure intensity (≥4 tons/year vs &lt;2.5 tons/year, HR = 7.9, 95% CI = 3.5–17.8; Ptrend =&lt;0.0001) and cumulative exposure (&gt;64 ton-years vs ≤28 ton-years, HR = 6.5, 95% CI = 1.5–28.3; Ptrend =0.003) during follow-up and over their lifetime was associated with increased IHD mortality, and ventilated stove use dramatically reduced this risk (HR = 0.2, 95% CI 0.1–0.5). Higher cumulative exposure to smoky coal during follow-up showed positive associations with IHD mortality, but the evidence for other metrics was less consistent compared with associations with smokeless coal use.

Conclusions
Higher use of smokeless coal, which is burned throughout China and is generally regarded to be a cleaner fuel type, is associated with IHD mortality. Use of cleaner fuels or stove interventions may be effective in reducing the increasing burden of IHD in developing regions that currently rely on smokeless coal for cooking and heating.