bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polyphosphoric acid (PPA): a new, highly efficient catalyst for the synthesis of functionalized azepino phthalazine hybrids
Authors: Lamera Esma , Chibani Aissa , Bouaziz Zouhair , Borgne Marc Le , Maadadi Ramzi , Bouraiou Abdelmalek 
Published: December 2024

Abstract
A new, convenient and efficient method for the construction of a new polycyclic condensed system containing an azepine and pyrazolophthalazine has been developed in the form of a two-step protocol comprising the condensation reaction of hydroxylamine with 1H-indazolo[1,2-b]phthalazine-1,6,11-trione derivative, followed by a Beckman rearrangement reaction using polyphosphoric acid (PPA) as catalyst. Various substituted substrates were successfully used, affording the azepino phthalazine hybrids in good yields and in short reaction times.
Nanostructured bismuth chloride based ((CH3NH3)3Bi2IxCl9-x) active layers for lead-free perovskite solar cells
Authors: Palanichamy Pavithrakumar , Madurai Ramakrishnan Venkatraman , Govindaraj Rajesh , Santhanam Agilan , Velauthapillai Dhayalan 
Published: December 2024

Abstract
Bismuth is one of the promising elements that can replace toxic lead in perovskite solar cells. However, surface roughness and inhomogeneous morphology with voids on the bismuth perovskite films limits their photovoltaic performance. In the present work, a scalable doctor-blade technique is employed to prepare perovskite thin film with high surface coverage. Methylammonium bismuth halide (MABiH) ((CH3NH3)3Bi2ClxI9-x) nanoparticles were synthesized by conventional sol-gel technique. The formation of perovskite structure was confirmed by X-ray diffraction measurement which confirmed that MABiH perovskite films were in hexagonal symmetry with polycrystalline nature. The prepared perovskite nanoparticles were deposited on mesoporous TiO2-coated FTO substrates through the spin coating technique and doctor blade method. Morphology analysis of MABiH perovskite revealed the formation of an orange Lily-like structure with higher surface coverage. Lead-free mesoporous perovskite solar cells prepared using MABiH perovskite material with carbon as hole extraction layer showed a maximum power conversion efficiency (PCE) of 0.004 %, with short circuit current density of 89 μA/cm2, open circuit voltage of 0.12 V and fill factor of 38 %. These results allow us to step toward fabricating bulk MABiH lead-free perovskite solar cells.
Structural, morphological and dielectric properties of Ni-doped ZnO nanoceramics prepared by Sol-gel method
Authors: Subhash Sunena , Kooriyattil Sudheendran 
Published: December 2024

Abstract
The objective of this work is to synthesize new set of nanoceramics that improves structural integrity and dielectric performance while maintaining the desired characteristics of ZnO with the introduction of regulated Ni-doping. By using the sol-gel process, Ni-doped ZnO nanoceramics were successfully synthesized. Zn1–xNixO (x = 0, 0.05, 0.01, 0.15) wt % of Ni in to Zn precursor salts were added. Doping levels are considered to be low to moderate level, which typically lead to considerable changes in structural, optical, morphological and dielectric properties without modification of the nature of host ZnO. Higher concentrations greater than 15 % can result in the precipitation of isolated Ni or NiO phases which may negatively influence uniformity and consistency of the doped material. By using XRD for structural study, phase purity and the hexagonal wurtzite structure were confirmed. The integration of Ni2+ ions into the ZnO lattice is indicated by the change in lattice parameters and bond length for the Ni-doped ZnO sample. Samples follow almost same c/a ratio of an average of 1.601. An increase in “Ni” content results a decrease in crystallite size. Average crystallite size has been calculated ranging from 43.88 nm to 17.01 nm for ZnO to Zn0.85Ni0.15O samples. According to SEM analysis, the grains of the samples are uniformly dispersed. When the produced NPs were examined for purity using EDAX analysis, it was found that the beginning stoichiometries and the chemical composition of Zn, Ni, and O agreed well. The development of the ZnO phase was verified by the presence of a peak at 523 cm−1 in the FTIR spectra. According to the findings of X-ray photoelectron spectroscopy (XPS), Ni was observed to be present in the ZnO lattice in the form of Ni2+.The Koops phenomenological theory and the Maxwell-Wagner model provide an explanation for the observed dielectric behaviour. It is noted that for pure ZnO, the dielectric constant and dielectric loss have maximum values, whereas for doped samples, these values decreases. Our sample is suitable for high frequency device application due to a negligible dielectric loss of 0.047 at 15 % Ni concentration in the high-frequency region. Ni-doping affects AC conductivity. At 10 MHz, Zn0.9Ni0.1O has the highest AC conductivity (2.654 × 10⁻⁴ (Ω cm)⁻1), while Zn0.85Ni0.15O shows a lower value (1.048 × 10⁻⁴ (Ω cm)⁻1), indicating a balance between doping level and grain boundary influence on conduction. The impedance study reveals that just one semicircle in all samples, indicating that the influence of grain boundaries is more significant than the contribution of individual grains.
ОТ НАУКИ К БИОТЕХНОНАУКЕ (О СМЫСЛЕ СДВИГА)
Authors: С.А. СМИРНОВ 
Published: December 2024

В статье дается анализ сдвига, который переживает в настоящее время наука как сфера деятельности и институт. Делается вывод, что происходит сдвиг от науки к технонауке, или, точнее, к биотехнонауке. Сдвиг означает смену базовой установки. В научной парадигме допускалась установка на познание мира и неизменность человека - субъекта познания. В технонаучной парадигме допускается, что мир и человека необходимо конструировать, менять под инженерные задачи преобразования. Человек как главный субъект изменений должен быть преобразован и улучшен. Вводится принцип улучшения человека с помощью современных умных технологий. В процессе сдвига от науки к технонауке граница между наукой, культурой, властью и обществом стирается и формируются гибридные формы, в которых базовым процессом становится производство новых форм жизни, в том числе и нового проекта человека. В этих гибридных формах научное знание перестает быть сугубо эпистемологической единицей, оно встраивается в большие инженерные проекты.
The article analyzes the shift that science is currently experiencing as a field of activity and an institution. It is concluded that there is a shift from science to technoscience or, more precisely, to biotechnoscience. This shift means a change in the basic setting. In the scientific paradigm, it was allowed to set on the knowledge of the world and the immutability of man as the subject of knowledge. In the techno-scientific paradigm, it is assumed that the world and man should be designed and changed to suit the engineering tasks of transformation. Man, as the main subject of change, should in principle be transformed and enhanced. The principle of human enhancement with the help of modern smart technologies is introduced. During shifting from science to technoscience, the boundary between science, culture, power and society becomes blurred and hybrid forms emerge, in which the production of new forms of life, including a new human project, becomes the basic process. In these hybrid forms, scientific knowledge ceases to be a purely epistemological unit, but integrates into large engineering projects.
Az új generációs genomszekvenálás lehetséges helye a kutyaharapások kezelésében
Authors: Tóth Imre , Tóth Adrienn Gréta , Solymosi Norbert 
Published: December 2024

Az antibiotikum-rezisztencia a modern orvoslás egyre több kihívást adó problémája. A kutyaharapás gyógyításának számos esetben elengedhetetlen része az antibiotikus kezelés. Az eredményes gyógyításhoz minél hamarabb ismerni kellene a kórokozókat és azok antibiotikum-érzékenységét. A jelenlegi módszerekkel – baktériumtenyésztés és antibiogram-készítés – napokba, akár hetekbe telhet, mire lelethez jutunk. A közben alkalmazott empirikus antibiotikum-kezelés újabb rezisztens törzseket szelektálhat ki. Az új generációs genomszekvenálással (NGS), illetve nanopore szekvenálással nyert genomszintű adatok gyors, teljes-körű mikrobiológiai lelet lehetőségét ígérik kutyaharapás esetében is. A harmadik generációs nanopore szekvenálás jövőbe mutató módszernek látszik a humán orvoslásban is a mikrobiológiai leletek elkészítésében.
Implementasi Pendidikan Akhlak Melalui Metode Pembiasaan Berkata Baik Pada Siswa SMP Al Amanah Cileunyi
Authors: Nurhamzah  , Nurdiana Agus 
Published: December 2024

Penelitian ini dilatar belakangi oleh maraknya permasalahan siswa yang berkaitan dengan akhlak, khususnya dalam berbicara dan berinteraksi terhadap guru dan sesama teman. Oleh sebab itu, maksud dari pada penelitian ini bertujuan untuk mengetahui implementasi pendidikan akhlak melalui metode pembiasaan berkata baik pada siswa di SMP Al-Amanah Cileunyi. Pendekatan penelitian adalah pendekatan kualitatif dengan menggunakan metode studi kasus. Teknik pengumpulan data dalam penelitian ini menggunakan tiga teknik yaitu observasi, wawancara dan dokumentasi. Hasil penelitian tentang implementasi pendidikan akhlak melalui metode pembiasaan berkata baik di SMP Al-Amanah Cileunyi menunjukan bahwa sudah terimpelemntasikannya pendidikan akhlak melalui pembiasaan berkata baik. Pembiasaan berkata baik di SMP Al-Amanah menekankan agar siswa selalu mengucapkan salam ketika masuk ke kelas dan ketika berpapasan dengan guru, tidak ragu untuk membiasakan mengucapkan maaf, tolong dan terima kasih terhadap sesama. Metode pembiasaan berkata baik di SMP Al-Amanah Cileunyi ditunjang dengan program-program pendukung seperti Perkembangan Kepribadian Muslim (PKM), Tafakur day dan program parenting.
Human oral microbiome as forensic biomarkers for individual identification: A systematic review
Authors: Nagaraj Vezhavendhan , Arumugam Vidhya , Muthanandam Sivaramakrishnan , Arumugam Santhadevy , Ramasamy Dhamodharan 
Published: December 2024

: The oral microbiome is a promising and novel source of biomarkers for forensic identification. It offers distinct signatures that may differentiate individuals, sparking new avenues of research and discovery.: This systematic review is meticulously designed to comprehensively consolidate current research on oral microbiome signatures in forensic contexts, leaving no stone unturned in our quest for knowledge. It focuses explicitly on microbial diversity, community structure, and specific taxa as potential markers for individual identification.s: To identify relevant studies published between 2014 and 2024, a comprehensive search of major scientific databases was conducted. Inclusion criteria encompassed peer-reviewed articles investigating oral microbiome diversity and specific microbial markers relevant to forensic individual identification. These studies were employed to evaluate the reliability and consistency of these biomarkers across diverse populations and environmental conditions.: The review included 13 studies that met the criteria, revealing significant associations between specific oral microbial taxa and individual identification. This systematic review highlighted consistent discriminatory power and stability of microbial signatures across varied populations.: Oral microbiome analysis is promising to enhance forensic investigations by providing unique biomarkers for individual identification. However, challenges such as standardization of microbiome studies and influences of environmental factors on microbiome underscore the need for further research to validate and effectively implement oral microbiome data in forensic practice.
Fearsome four- Fungal infections in renal transplant recipients
Authors: Rajesh Chilaka , Mishra Utkarash , John Elenjickal Elias , Thomas Athul , Eapen Jeethu Joseph , Michael Joy Sarojini , Varughese Santosh 
Published: December 2024

To study the clinical presentation, diagnostic methods, treatment and outcomes of Invasive Aspergillosis Cryptococcal infection, Mucormycosis and Histoplasmosis in renal transplant recipients. : We performed a retrospective analysis of renal transplant recipients with four major fungal infections from January 2000 until December 2022 at a tertiary care centre in Southern India. This study was approved by the institutional ethical committee. We have identified these cases from the electronic records of the microbiology department and renal transplant outpatient clinic. A total of 1970 patients underwent renal transplantation at this institute during study period. A total of 25 patients were diagnosed as having invasive Aspergillosis - 20 patients had pneumonia, three had right maxillary sinusitis, one each had left chronic suppurative otitis media, and skull base osteomyelitis). There were 20 patients with cryptococcal infection of which eight had disseminated infection, seven had meningitis, four had cutaneous cryptococcosis and one had pulmonary cryptococcosis. Mucormycosis was diagnosed in 14 patients, twelve of which had pulmonary mucormycosis, one had oculo-cerebral mucormycosis and one patient had acute invasive fungal maxillarysinusitis. Histoplasmosis was diagnosed in four patients, two of whom had disseminated histoplasmosis and two had cutaneous histoplasmosis. In this study, mortality was highest with mucormycosis (57%) followed by 33.3% with invasive Aspergillosis and 20% with Cryptococci infection. Currently, there is no standard serological test available for the routine identification of invasive fungal infections in patients. Initial cultures may yield negative results due to slow fungal growth and variations in colony appearance. Therefore, it is essential to pursue aggressive sampling methods when fungal infection is suspected. Invasive procedures such as bronchoscopic lavage and abscess aspiration play a crucial role in reaching a diagnosis. In summary, maintaining a high level of suspicion and employing thorough investigations in post-renal transplant recipients are vital for early diagnosis, prompt treatment initiation, prevention of disease spread, and reduction of mortality risk.
Uterine fibroid in the premenopause: experience of medication treatment
Authors: Kravchenko О.V. 
Published: December 2024

Objectives of the study: to evaluate the effectiveness of the progestogens for the treatment of uterine fibroids (UF) in women in the premenopausal period.Materials and methods. 42 patients aged 45–50 years with UF were examined. The diagnosis of UF was verified according to clinical and instrumental research methods. The effectiveness of the therapy was evaluated according to clinical and ultrasound examination data before and during the course of treatment. All patients with diagnosed symptomatic UF received progestogen dienogest 2 mg ones a day continuously for a year, with clinical and sonographic control every 3 months.Results. UF was symptomatic in all examined patients. According to the International Federation of Gynecology and Obstetrics (FIGO) classification system for UF, 42.8% (18) of women had type III–IV nodes, 54.8% (23) had type II–V nodes, and 2.4% (1) of women had type VI nodes. In all patients were 2 or more nodes.Already after 6 months of therapy, bleeding complaints decreased by more than 8 times, moderate pain syndrome and urination disorders were noted in only one (2.4%) patient. After 12 months, pelvic pain and bladder dysfunction were absent in 100% of cases. One (2.4%) patient had spotting bleeding for 2 days during the 8th month of treatment. After 6 and 12 months of treatment, the size of the endometrium decreased significantly to 3.6–7 and 3.2–4.6 mm, respectively. The total volume of the uterus also underwent positive changes: it decreased by 10–40% in each patient during the course of treatment.Conclusions. It should be preferred progestogens in the treatment of UF in women aged 45–50 years who wish to preserve the uterus. Therapy with dienogest in a continuous long-term regimen showed high clinical effectiveness, confirmed the active antiproliferative, antiovulatory effect of the drug in the absence of estrogen deficiency symptoms, which is important for this age group of patients.
Sero-prevalence of Hepatitis C infection among the Municipal Waste collectors in Aden, Yemen
Authors: Gubran Ali N.M. , Altuhaish Adeel Abdulkarim Fadhl , Waleed Hana , Abdullah Aisha  Ali , Ali Ayat  Gamal , Saeed Bona  Mohammad , Omar Nadrah  Aidroos , Abdullah Nawras  Hamza  , Saeed Doa'a  Anwer  Mohammed , Naji   Taha Abdo Ali , Taleb Adel Gamal Abdulrab , Manea Fatima Adel Mohammed , Mohammed Fatima Mohammed Abdulhameed , Awadh Fatima Mohammed Ghaleb , Nasr Gamilah Nasser Rageh , Ben Mohammed Mustafa Nadhmi Mohammed , Al-labni Mohammed Abdullah 
Published: December 2024

Objectives: Hepatitis C virus infection is major global health problem. The present study was aimed to determine the prevalence of Hepatitis C infection among municipal waste collectors and to identify clinical findings and risk factors associated with HCV infection among those collectors in Aden, Yemen. Methods: A cross-sectional study was conducted on 100 municipal waste collectors. The blood samples were collected from all MWCs, then the clotted blood was separated by centrifuge and the sera were tested for presence of HCV antibodies (Anti-HCV) by Cobas technique that based on ECLIA. Results: Out of 100 municipal waste collectors, majority was males 89(89/100). The total mean age of those members was 36.74±10.98years. The range of ages was 16 and 60 years. Only 1(1/100) had HCV infection. This case was male, married and within age group ≥ 45years which comprised; 1.1%, 1.2% and 4.5%, respectively. The positive case was illiterate and had low economic status and had duration of work as municipal waste collector from 10-20years and alone accommodation which comprised 1.1%, 1.6% 2.4% and 9.1%, respectively. This 1(7.8%) HCV infected patient infection lives in Al-Muallhe. Significant associations found between HCV infection and exposing to blood transfusion, catheterization and needles stick as risk factors (p=0.002,0.0001 and 0.080), respectively and liver cirrhosis as complicated clinical finding (p=.0001),but the association was not significant between HCV infection and sources of waste (0.620).
Conclusion: It can be concluded from this study that the municipal waste collectors in Aden, Yemen had lower rate of HCV infection than most studies globally. The males, married and MWCs in age group≥ 45years, and those had illiterate education and live alone had highest percentages of HCV infection. Blood transfusion, needles stick and catheterization may increase the risk of HCV infection.
Pemanfaatan Mobile JKN Untuk Meningkatkan Efektifitas Pelayanan
Authors: Sari Erika Novita , Muslikhah RR. Siti , Maisaroh  
Published: December 2024

The Mobile JKN application is a government innovation in the health sector managed by BPJS Kesehatan in providing public services to participants. This Mobile JKN application is expected to reduce queues at each BPJS Kesehatan branch office by helping to serve all participant administrative activities. However, many people do not have the Mobile JKN application and still, many participants come to the office for services. This study aims to determine the use of the Mobile Health Insurance (JKN) application to increase the effectiveness of services at BPJS Kesehatan Wonogiri Regency. This study uses a qualitative descriptive approach and data collection techniques through observation, interviews, and documentation. This study took informants as many as one staff and nine BPJS Kesehatan Wonogiri Regency participants. The study results show that participants' understanding and awareness of the Mobile JKN application is still low. The use of the National Health Insurance Mobile (JKN) application at BPJS Kesehatan Wonogiri Regency has been running. Still, it has not been effective and efficient in terms of measures of effectiveness, namely, program understanding, target accuracy, timeliness, achievement of goals, and real changes. The obstacles participants face in using the application are system disruptions, full storage of participants' mobile phones, and networks, participants who do not understand the application, and incomplete login requirements.
Keywords: Utilization, Mobile JKN Application, Service Effectiveness
The Choice of a Construction Arrangement for Cable Lines with a Voltage of 10 kV According to the Criterion of the Minimum Expected Cost
Authors: Vysotski M. E. 
Published: December 2024

The article considers the issue of choosing the optimal construction arrangement of cable lines with a voltage of 10 (20, 35) kV with cross-linked polyethylene insulation. The options for using three or single-core cables laid in a triangle or in a plane are analyzed. The methodological basis of the work is the principle of minimizing the expected costs, taking into account both capital investments and annual costs, including losses of electrical energy in cables. Within the framework of the study, a nomogram of economic intervals was scheduled, which makes it possible to determine the optimal cable core sections and boundary conditions for the use of threeand single-core cables, depending on the calculated current load. It is shown that with the existing nomenclature of three-core cables with a maximum core cross-section up to 630 mm2, single-core cables can be economically feasible only with a core cross-section of 800 mm2 and above. It has been discovered that the expected costs for laying single-core cables in the plane with two-way grounding of screens always turn out to be higher than when laying a triangle. This effect is due to an increase in both capital costs and power losses in cable screens. To increase the efficiency of cable lines, it is proposed to expand the range of three-core cables by including cables with the maximum possible core cross-section. This will make possible to increase the range of current loads in which the use of three-core cables will be economically justifiable. The results presented in the article can be used in the design of new cable lines, the analysis of the effectiveness of existing ones, as well as in the modernization and reconstruction of urban medium-voltage cable networks.