bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilidad de la teoría de la conducta planificada para entender el consumo de frutas y verduras: evidencia de estudios en adultos y adolescentes chilenos = Usefulness of the theory of planned behavior to understand the consumption of fruits and vegetables: evidence of studies on Chilean adults and adolescents
Authors: Peña-y-Lillo Macarena Sofia 
Published: June 2019

Este artículo presenta dos estudios cuantitativos con diseño descriptivo no experimental. El primero corresponde a una encuesta transversal cara a cara a adultos de 18 a 78 años de segmentos socioeconómicos medios y bajos (N = 250). El segundo corresponde a una encuesta longitudinal autoaplicada en adolescentes de sexo femenino de 12 a 18 años (N = 751). El propósito de ambos estudios fue explorar las asociaciones de los constructos de la teoría de la conducta planificada (TCP) en el contexto del consumo de frutas y verduras en la población chilena. Los datos se analizaron utilizando regresiones múltiples y jerárquicas. En los dos estudios se encontró que las actitudes, normas sociales y percepciones de control estaban significativamente asociadas con las intenciones. Las intenciones, en tanto, tenían una asociación transversal con la conducta. Los hallazgos de este estudio subrayan la utilidad de la TCP para guiar intervenciones para promover una alimentación saludable, en especial, la importancia de las actitudes y las percepciones de control.Palabras clave: dieta saludable; actitudes; percepciones de control conductual; auto-eficacia; promoción de la salud.Abstract Introduction: The theory of planned behavior (TPB) proposes that human behavior can be explained as a function of intentions to perform a given behavior, which in turn are determined by attitudes, normative perceptions and perceptions of control. The model has been extensively recommended and utilized to guide the design of public health communication interventions. Goals: The purpose of this work is to explore the associations of the TPB constructs in the context of fruit and vegetable consumption in the Chilean population. Methods: Two quantitative studies with a descriptive non-experimental design were conducted. The first corresponds to a face-to-face cross-sectional survey of adults 18 to 78 years of medium and low socioeconomic status (N = 250). The second corresponds to a longitudinal self-applied survey of female adolescents 12 to 18 years old (N = 751). The data were analyzed using multiple and hierarchical regressions. Results: In both studies, it was found that attitudes, norms and perceptions of control were significantly associated with intentions. Intentions, in turn, had a cross-sectional association with behavior. Conclusion: This study’s findings underscore the usefulness of the TPB to guide interventions aimed at promoting healthy eating, especially the importance of attitudes and perceptions of control for this purpose.Keywords: healthy diet; attitudes; perceived behavioral control; self-efficacy; health promotion.
HIV/AIDS-Related Knowledge and Willingness to Participate in Voluntary Counseling and Testing among Health Sciences University Students
Authors: Sari Ni Putu Wulan Purnama , Parut Anselmus Aristo 
Published: June 2019

Introduction: Health sciences university students (HSUS) are susceptible to HIV infection due to frequent contact with patients whose HIV status is unknown. This study aimed to compare the HIV/AIDS-related knowledge and the willingness to participate in VCT among HSUS, analyzing the differences between groups, and correlation and effect between variables. Methods: This cross-sectional study involved 357 HSUS from the faculty of nursing, pharmacy, psychology and medicine at an accredited university. Samples were selected using simple random sampling. Data analysis used descriptive statistic, Pearson correlation, one-way ANOVA test, and linear regression test (α<0.05).Results: Most respondents were 20-21 years old single female who still live with parents, exposed to HIV/AIDS material twice/more via academic activities; lack of HIV/AIDS-related knowledge (51.5%), highest mean found in medical students (73.1%); willing enough to participate in VCT (83.5%), highest mean found in nursing students (86.4%). No correlation found between variables (p=0.101), and the regression model was not significant (p=0.101). HIV/AIDS-related knowledge contributed only 0.8% influence on the willingness to participate in VCT among HSUS (R2=0.008), other unidentified factors possibly play a more important role.Conclusion: Besides knowledge, other factors like demographic factors, social determinants, close person, health education, fear, and HIV-related stigma may affect the willingness to participate in VCT among HSUS. HSUS's knowledge about HIV/AIDS was low but their willingness to participate in VCT was quite high. HIV/AIDS-related knowledge has a slight contribution in determining HSUS's willingness to participate in VCT. Further analysis of other potential factors is needed to determine stronger predictors.
KAMU HASTANELERİNDE İŞ SAĞLIĞI ve GÜVENLİĞİ UYGULAMALARININ ÇALIŞANLARIN İŞ PERFORMANSINA ETKİSİ: BURDUR İLİ ÖRNEĞİ - THE EFFECT OF OCCUPATIONAL HEALTH AND SAFETY PRACTICES ON WORK PERFORMANCE OF PUBLIC HOSPITALS: BURDUR PROVINCE CASE
Authors: KAVGACI Yüksel , ÇİÇEK Hüseyin 
Published: June 2019

Araştırmanın amacı kamu hastanelerindeki iş sağlığı ve güvenliği uygulamalarının, çalışanların iş performansı üzerine etkilerini ortaya koymaktır. Araştırmanın evrenini Mayıs 2016 tarihi itibarı ile Burdur ilindeki 4 kamu hastanesinin kadrolu çalışanları oluşturmaktadır. Araştırmada kolayda örnekleme yöntemi kullanılmıştır. Örneklemi oluşturan 554 çalışana ulaşmak için 800 anket gönderilmiş, bunlardan 570 tanesi geri dönmüş ve 554 anket değerlendirmeye alınmıştır. Verilerin toplanmasında hastanede çalışan sağlık personeli için iş güvenliği ölçeği, iş sağlığı ve güvenliği ölçeği ve iş performansı ölçeği kullanılmıştır. Bağımlı değişken olan iş performansı ile bağımsız değişken olan İSG uygulamalarının alt faktörleri arasındaki ilişkileri belirlemek için Pearson Korelasyon analizi ve etkileri ortaya koymak için Çoklu Regresyon analizinden faydalanılmıştır.Araştırmanın sonucunda İSG uygulamaları alt boyutlarının tamamının iş performansı ile pozitif yönlü doğrusal ilişkisi olduğu, çoklu regresyon analizi sonucuna göre sağlık taraması ve kayıt sistemleri, malzeme, araç ve gereç denetimi ile koruyucu önlemler ve kurallar alt boyutlarının iş performansını pozitif yönlü ve anlamlı şekilde etkilediği, diğer alt boyutlarının anlamlı olmadığı sonucuna ulaşılmıştır. Çalışanların hasta veya hasta yakını tarafından sözel veya fiziksel şiddete maruz kalma oranı %90,2, hastane çalışanları tarafından sözel veya fiziksel şiddete maruz kalma oranı %57,2 çıkmıştır. Bu yüksek oran kamu hastanelerinde yaşanan şiddet ve mobingi ortaya koymaktadır.
Harnessing Progress in Psychiatric Genetics to Advance Population Mental Health
Authors: Merikangas Kathleen Ries , Merikangas Alison K. 
Published: June 2019

Advances in genomics and neuroscience have ushered in unprecedented opportunities to increase our understanding of the biological underpinnings of mental disorders, yet there has been limited progress in translating knowledge on genetic risk factors to reduce the burden of these conditions in the population. We describe the challenges and opportunities afforded by the growth of large-scale population health databases, progress in genomics, and collaborative efforts in epidemiology and neuroscience to develop informed population-wide interventions for mental disorders. Future progress is likely to benefit from the following efforts: expansion of large collaborative studies of mental disorders to include more systematically ascertained multiethnic samples from biobanks and registries, harmonization of phenotypic characterization in registry and population samples to extend clinical diagnosis to transdiagnostic concepts, systematic investigation of the influences of both specific and nonspecific environmental factors that may combine with genetic susceptibility to confer increased risk of specific mental disorders, and implementation of study designs that can inform gene–environment interactions. Such data can ultimately be combined to develop comprehensive models of risks of, interventions for, and outcomes of mental disorders. With its focus on phenotypic characterization, sampling, study designs, and analytic methods, epidemiology will be central to progress in translating genomics to public health.
Disparities in Access to Health Care Among US-Born and Foreign-Born US Adults by Mental Health Status, 2013–2016
Authors: Dedania Reema , Gonzales Gilbert 
Published: June 2019

Objectives. To compare access to care between US-born and foreign-born US adults by mental health status. Methods. We analyzed data on nonelderly adults (n = 100 428) from the 2013–2016 National Health Interview Survey. We used prevalence estimates and multivariable logistic regression models to compare issues of affordability and accessibility between US-born and foreign-born individuals. Results. Approximately 22.2% of US-born adults and 18.1% of foreign-born adults had symptoms of moderate to severe psychological distress. Compared with US-born adults with no psychological distress, and after adjustment for sociodemographic characteristics, US-born and foreign-born adults with psychological distress were much more likely to report multiple emergency room visits and unmet medical care, mental health care, and prescription medications because of cost. Conclusions. Our study found that adults with moderate to severe psychological distress, regardless of their immigration status, were at greater risk for reporting issues of affordability when accessing health care compared with US-born adults with no psychological distress. Public Health Implications. Health care and mental health reforms should focus on reducing health care costs and establishing innovative efforts to broaden access to care to diverse populations.
Modeling the Interaction Between Natural and Hydraulic Fractures Using 3D Finite-Element Analysis
Authors: Nikam Aditya , Awoleke Obadare O. , Ahmadi Mohabbat 
Published: June 2019

Summary
We built a 3D geomechanical model using commercially available finite–element–analysis (FEA) software to simulate a propagating hydraulic fracture (HF) and its interaction with a vertical natural fracture (NF) in a tight medium. These newly introduced elements have the ability to model the fluid continuity at an HF/NF intersection, the main area of concern.
We observed that, for a high–stress–contrast scenario, the NF cohesive elements showed less damage when compared with the low–stress–contrast case. Also, for the scenario of high stress contrast with principal horizontal stresses reversed, the HF intersected, activated, and opened the NF. Increasing the injection rate resulted in a longer and wider HF but did not significantly affect the NF–activated length. Injection–fluid viscosity displayed an inverse relationship with the HF length and a proportional relationship with the HF opening or width. We observed that a weak NF plane temporarily restricts the HF propagation. On the other hand, a tougher NF, or an NF with properties similar to its surroundings, does not show this type of restriction. The NF activated length was found at its maximum in the case of a weaker NF and at nearly zero in the case of a stronger NF and an NF that has strength similar to its surroundings.
In this study we present the results for a three–layered 3D geomechanical model with a single HF and NF orthogonally intersecting each other, using newly introduced cohesive elements for the first time in technical literature. We also conducted a detailed sensitivity analysis considering the effect of stress contrast, injection rate, injection–fluid viscosity, and NF properties on this HF/NF interaction. These results provide an idea of how the idealized resultant fracture geometry will change when several fracture/fracture treatment properties are varied.
The prevalence and risk factors of Early Childhood Caries among 3-year-old children in Wenzhou
Authors: Mei Liqin , Wei Zhiyuan , Li Qiao , Wang Xiping 
Published: June 2019

Abstract
Background: This study aimed to investigate the prevalence and risk factors of Early Childhood Caries (ECC) among 3-year-old children in Wenzhou China.
Methods: Preschool children aged 3 were recruited using a stratified cluster sampling method. Dental examinations were carried out by one trained dentist, and oral health-related data were collected. Examinations were surface-specific for dental caries, following World Health Organization (WHO) criteria. Bivariate tests and logistic regression models were used to investigate the risk factors of dental caries.
Results: A total of 693 children were recruited for the study, and 445 completed the dental examination. Among the 445 children, the prevalence of ECC was 59.8%. The mean decayed, missing, and filled primary teeth (dmft) was 2.9, and of the total dmft, only 6.3% were filled. The mean decayed, missing, and filled primary surface (dmfs) was 4.9. Logistic regression analyses identified age and parents’ oral health knowledge level were associated with the experience of ECC (P<0.05).
Conclusions: A higher prevalence of ECC was observed and most of the carious teeth were not restored. The experience of ECC was related to age and parents’ oral health knowledge level.
Comparison between Ologen implant and Mitomycin C in trabeculectomy: A Systematic Review and Meta-Analysis
Authors: Liu Xiaoyan , Du Yali , Lei Min , Zhuang Leyi , Lv Peng 
Published: June 2019

Abstract
Objective

To evaluate the effectiveness and safety of the biodegradable collagen matrix (Ologen) implant in trabeculectomy.

Research design and methods

We searched Pubmed, Cochrane library, Embase and Web of Science databases to find studies that met our pre-stated inclusion criteria. Reference lists of retrieved articles were also reviewed. The search was finished by February 2019. Study selection, data extraction, quality assessment, and data analyses were performed according to the Cochrane standards. Either a fixed or a random-effects model was used to calculate the overall combined risk estimates. The efficacy measures were the weighted mean differences (WMDs) for the intraocular pressure reduction (IOPR) and the glaucoma medications reduction, the odds ratio (OR) for the success rate and adverse events.

Results

Fifteen randomized controlled trials involved 682 eyes were included in the meta-analysis. There were no statistically differences between two groups in the IOPR at any time postoperatively. The MD of the IOPR was [MD= -0.45,95% Confidence Interval (CI), (-2.36,1.46), P=0.65] at one day, [MD= -0.82,95% CI, (-1.97, 0.33), P=0.16] at one week, [MD= -1.33, 95% CI,(-3.12, 0.47), P=0.15] at one month, [MD= 0.11,95% CI, (-1.87, 2.08), P=0.92] at three months, [MD= -0.60,95% CI, (-2.27, 1.06), P=0.48] at six months, [MD= -0.33,95% CI, (-1.99, 1.32), P=0.69] at one year, [MD= -0.13,95% CI, (-1.90, 1.65), P=0.89] at two years, [MD= 2.54,95% CI, (-2.83, 7.90), P=0.35] at three years, [MD= 3.04,95% CI, (-3.95, 10.03), P=0.39] at five years. There was no statistically significant difference between the Ologen groups and MMC groups concerned the complete success rate [OR=1.19, 95%CI, (0.83, 1.71), P=0.35]. With regard to the adverse events, no obvirously significance was observed. Seven studies reported the change of antiglaucoma medications. We found that the change of antiglaucoma medications is higher in MMC groups than that in Ologen groups [MD=-0.18, 95%CI, (-0.33, -0.03), P=0.02]. There is no significant difference in complications between the two groups.

Conclusions

From the current evidence, Ologen may be an alternative choice for trabeculectomy when considering the efficacy and safety. However, MMC might be the preferred choice concerned cost-effectiveness.
The Prevalence of Obstructive Sleep Apnea in Mild Cognitive Impairment: A Systematic Review
Authors: Mubashir Talha , Abrahamyan Lusine , Niazi Ayan , Piyasena Deween , Arif Abdul A. , Wong Jean , Osorio Ricardo S. , Ryan Clodagh M. , Chung Frances 
Published: June 2019

Abstract
Background: Previous studies have shown that obstructive sleep apnea (OSA) is associated with a higher risk of cognitive impairment or dementia in the elderly, leading to deleterious health effects and decreasing quality of life. This systematic review aims to determine the prevalence of OSA in patients with mild cognitive impairment (MCI) and examine whether an association between OSA and MCI exists. Methods: We searched Medline, PubMed, Embase, Cochrane Central, Cochrane Database of Systematic Reviews, PsychINFO, Scopus, the Web of Science, ClinicalTrials.gov and the International Clinical Trials Registry Platform for published and unpublished studies. We included studies in adults with a diagnosis of MCI that reported on the prevalence of OSA. Two independent reviewers performed the abstract and full-text screening, data extraction and the study quality critical appraisal. Results: Five studies were included in the systematic review. Overall, OSA prevalence rates in patients with MCI varied between 11−71% and were influenced by OSA diagnostic methods and patient recruitment locations (community or clinic based). Among studies using the following OSA diagnostic measures– self-report, ApneaLink, Berlin Questionnaire and polysomnography– the OSA prevalence rates in MCI were 11%, 27%, 59% and 70%, respectively. In a community-based sample, the prevalence of OSA in patients with and without MCI was 27% and 26%, respectively. Conclusions: Based on limited evidence, the prevalence of OSA in patients with MCI is 27% and varies based upon OSA diagnostic methods and patient recruitment locations. Our findings provide an important framework for future studies to prospectively investigate the association between OSA and MCI among larger community-based cohorts and implement a standardized approach to diagnose OSA in memory clinics. PROSPERO registration: CRD42018096577
Factors controlling the crystal morphology and chemistry of garnet in skarn deposits: A case study from the Cuihongshan polymetallic deposit, Lesser Xing'an Range, NE China
Authors: Fei Xianghui , Zhang Zhaochong , Cheng Zhiguo , Santosh M. 
Published: June 2019

Abstract
The grossular-andradite solid solutions in garnet from skarn deposits in relation to hydrothermal processes and physicochemical conditions of ore formation remain controversial. Here we investigate garnet occurring in association with calcic and magnesian skarn rocks in the Cuihongshan polymetallic skarn deposit of NE China. The calcic skarn rocks contain three types of garnets. (1) Prograde type I Al-rich anisotropic garnets display polysynthetic twinning and a compositional range of Grs18–80Adr10–75. This type of garnet shows markedly low rare earth element (REE) contents (3.27–78.26 ppm) and is strongly depleted in light rare earth elements (LREE, 0.57–44.65 ppm) relative to heavy rare earth elements (HREE, 2.31–59.19 ppm). They also display a significantly negative Eu anomaly (Eu/Eu* of 0.03–0.90). (2) Fe-rich retrograde type II garnets are anisotropic with oscillatory zoning and own wide compositional variations (Grs1–47Adr30–95) with flat REE (13.73–377.08 ppm) patterns. (3) Fe-rich retrograde type III isotropic garnets display oscillatory zoning and morphological transition from planar dodecahedral {110} crystal faces to {211} crystal faces in the margin. Types III garnets exhibit relatively narrow compositional variations of Grs0.1–12Adr85–97 with LREE-enrichment (0.80–51.87 ppm), flat HREE patterns (0.15–2.46 ppm) and strong positive Eu anomalies (Eu/Eu* of 0.93–27.07 with almost all >1). The magnesian skarn rocks contain euhedral isotropic type IV Mn-rich garnet veins with a composition of Grs10–23Sps48–62Alm14–29. All calcic garnets contain considerable Sn and W contents. Type II garnet containing intermediate compositions of andradite and grossular shows the highest Sn contents (64.36–2778.92 ppm), albeit the lowest W range (1.11–468.44 ppm). Birefringence of garnet is probably caused by strain from lattice mismatch at a twinning boundary or ion substitution near intermediate compositions of grossular-andradite. The fine-scale, sharp, and straight garnet zones are probably caused by self-organization, but the compositional variations of zones from core to rim are probably caused by external factors. The zoning is likely driven by external factors such as composition of the hydrothermal fluid. REE concentrations are probably influenced by the relative proportion and temperature of the system. Moreover, the LREE-HREE fractionation of garnet can be attributed to relative compositions of grossular-andradite system. The W and Sn concentrations in garnet can be used as indicators for the exploration of W-Sn skarn deposits.
Chemical and Bioactive Marine Natural Products of Coral-Derived Microorganisms (2015-2017)
Authors: Hou Xue-Mei , Hai Yang , Gu Yu-Cheng , Wang Chang-Yun , Shao Chang-Lun 
Published: June 2019

:
Coral-derived microorganisms are known for their inherent ability to produce novel
products of pharmaceutical importance. Nearly 260 marine natural products (MNPs) have been isolated
from coral-derived microorganisms till 2014. In the last three years, 118 MNPs have been
isolated from coral-associated microorganisms including 46 new compounds, two with a novel
skeleton, and four new natural products. Most of them exhibited in vitro or in vivo activities against
tumor cell lines, parasites, pathogenic bacteria, fungi and virus. We reviewed the natural products
reported from 2015 to 2017 that have a wide range of bioactivities against different biological targets.
Hepatic Artery and Peripheral Vein Pharmacokinetics of Raltitrexed in Swine After the Administration of a Hepatic Arterial Infusion
Authors: Zhu Linzhong , Zheng Nan , Li Xingang , Zhang Xiaofeng 
Published: June 2019

Background:
Hepatic Arterial Infusion (HAI) with raltitrexed has become an effective treatment for hepatocellular
cancer and colorectal cancer liver metastases. However, traditional Body Surface Area (BSA)-based dosing
is unsafe or ineffective, and a more accurate model-based approach is required.

Methods:
In this study, domestic swine were given 1 mg or 4 mg raltitrexed administered by an HAI with infusion
times of 30, 60 and 120 min. Hepatic Artery (HA) and Peripheral Vein (PV) samples were collected, and a twocompartment
model with an elimination pathway was established to describe the in vivo behavior of raltitrexed.

Results:
The clearance was 0.27 L/min, and the volumes of distribution were 0.35 and 6.65 L for the HA and PV
compartments, respectively. The goodness-of-fit plots and visual predictive checks suggested that the proposed
pharmacokinetic model agreed well with the observations.

Conclusion:
The pharmacokinetic model could be helpful in quantitatively describing the detailed processes of raltitrexed
activity administered by HAI and determining an appropriate dosing regimen for preclinical and clinical
studies.