bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Restrictive Infusion on VAP after Colorectal Cancer in Elderly Patients
Authors: Zheng Chen 
Published: July 2018

Objective:Â To investigate the effect of restrictive infusion onÂ ventilator-associated pneumonia (VAP) in elderly patients withÂ colon cancer treated by operation. Methods: A total of 62 elderly patients underwent colon cancer from January 2015 toÂ March 2016 were randomly divided into study group and control group. The patients in the study group were treated withÂ restrictive rehydration strategy, central venous pressure (CVP)Â 5 ~ 7 cmH 2 O, the control group rubbed with conventional re-hydration program; the remaining treatment of the two groupsÂ of patients to maintain consistency. Results: There was noÂ significant difference in MAP, HR and CO between the studyÂ group and the control group at the time of T0 ~ T4 (P> 0.05).Â The infusion volume of the study group was significantly lower than that of the control group (P (P < 0.05). There was noÂ significant difference in the levels of LAC, IL-6 and TNF-Î±Â between the two groups (P > 0.05). There was no significantÂ difference in the levels of LAC, IL-6 and TNF-Î±Â between theÂ study group and the control group (P < 0.05). After treatment,Â the levels of IL-6 and TNF-Î±Â in the study group were significantly lower than those in the control group (P <0.05). ThereÂ was no significant difference in the CPIS score between theÂ two groups (P > 0.05). On the 3rd and 7th day after operation,Â the CPSI score of the study group was significantly lower thanÂ that of the control group (P < 0.05). Conclusion: The restrictive infusion has no obvious effect on the hemodynamics ofÂ elderly patients with colon cancer treated by surgery, but it canÂ reduce the risk of VAP.
Clinicopathological Features of Simple Primary Squamous Cell Carcinoma of Breast
Authors: Kong Lingquan 
Published: July 2018

Objective: To investigate the clinicopathological features andÂ prognosis of primary squamous cell carcinoma of the breast.Â Methods:Â 2 cases of primary squamous cell carcinoma of theÂ breast were analyzed. According to the TNM stage of breastÂ cancer, the patients underwent hematectomy and stage IV andÂ stage II. All the patients were treated with radiotherapy. Results:Â The age of onset was younger, ER / PR was negative,Â and 4 months after operation, no recurrence or distant metastasis was found. Conclusion: The clinical features of primaryÂ squamous cell carcinoma lack specificity, misdiagnosis, needÂ to pay attention to differentialÂ diagnosis, standardized diagnosis and treatment strategy still need further study.
Perioperative Management of Patients with Breast Cancer Complicated with Rheumatic Heart Disease
Authors: Liu Hong 
Published: July 2018

Objective:Â To investigate the perioperative treatment of patients with breast cancer complicatedÂ with rheumatic heartÂ disease. Methods:Â The perioperative treatment of rheumaticÂ heart disease in 2400 patients with breast cancer treated inÂ our hospital from January 2007 to August 2011 were retrospectively analyzed. Results: Two of the 2400 patients withÂ breast cancer had rheumatic heart disease, aged 71 and 55Â years, respectively. One case with atrial fibrillation, and theÂ other one case of mitral valve replacement valve, were treatedÂ with warfarin anticoagulant therapy. Two patients in the first 5Â days before the withdrawal of warfarin, while low molecularÂ weight heparin or fondaparinux sodium anticoagulant therapy,Â intraoperative careful hemostasis, as appropriate after the startÂ of anticoagulant therapy. Patients within 24 hours after the incision area ofÂ ecchymosis, to adjust the anticoagulant drugs,Â to strengthen the drainage and hemostasis and other measuresÂ improved. Conclusion: Patients with breast cancer complicated with rheumatic heart disease are more complicated due toÂ basic diseases, and their perioperative treatment is more complicated. Excessive anticoagulation or hemostatic treatmentÂ will lead to adverse reactions. Perioperative attention shouldÂ be paid to monitor and adjust the patient INR value, intraoperative need to carefully hemostasis, as far as possible to stopÂ bleeding, reduce coagulation, close observation of patientsÂ with local wound conditions, strengthen drainage, if necessary,Â add hemostatic, and more can be better The treatment effect.
Effects of Fresh Royal Jelly on the Proliferation of Human Hepatoma Cell Line SMMC-7721
Authors: Wang Mingmin 
Published: July 2018

Objective:Â To investigate the effect of fresh royal jelly on theÂ proliferation of human hepatoma cell line SMMC-7721. Methods:Â We found that the administration of fresh royal jelly couldÂ alleviate the condition of hepatocellular carcinoma patients in aÂ certain extent. The human hepatocellular carcinoma cell lineÂ SMMC-7721 was cultured in vitro. MTT colorimetric method wasÂ used to treat fresh cells and serum containing human serum. TheÂ effect of SMMC-7721 proliferation was observed. Results: TheÂ aqueous solution of fresh royal jelly had a certain effect on theÂ proliferation of hepatoma cell line SMMC-7721 in aÂ dose-dependent manner. The serum containing fresh royal jellyÂ could inhibit the proliferation of human hepatoma cell lineÂ SMMC-7721, and its inhibitory effect showed dose-dependent.Â Conclusion:Â The serum containing fresh royal jelly has aÂ significant inhibitory effect on the proliferation of humanÂ hepatoma cell line SMMC-7721 and its anti-cancer effect may beÂ derived from its metabolitesÂ or stimulating the formation ofÂ immune-reactive substances in the body, in whichÂ in the clinical treatment of liver cancer and research have a certainÂ value.
Application of Traditional Chinese Medicine Combined with TACE in Patients with Primary Hepatocellular Carcinoma and Its Effect on Liver Function
Authors: Ding Haibin 
Published: July 2018

Objective: To analyze the effects of Chinese herbal medicineÂ combined with transcatheter arterial chemoembolization (TACE)Â on liver function in patients with primary hepatocellularCarcinomaÂ (HCC). Methods:Â 122 patients with primary hepatocellularÂ carcinoma admitted inÂ our hospital from March 2014 to OctoberÂ 2016 were divided into experimental group and control groupÂ according to the digital table. The number of each group was theÂ same. The patients in the control group were treated byÂ transcatheter arterial chemoembolization. The experimental groupÂ was treated with traditional Chinese medicine on the basis of theÂ control group. SPSS20.0 statistical software for statistical analysisÂ of two groups of patients with short-term effect, follow-up of oneÂ year primary liver cancer recurrence rate, before and afterÂ treatment WBC count, liver function (alanine aminotransferase),Â alpha-fetoprotein and Karnofsky index parameters. Results:Â â‘ TheÂ total effective rate of the experimental group was significantly higherÂ than that of the control group (P <0.05); â‘¡The relapse rate of theexperimental group was significantly lower than that of the controlÂ group (P <0.05); â‘¢ Before the treatment, the patients in the twoÂ groups had significantly higher recurrence rate than those in theÂ control group (P <0.05). After treatment, the white blood cellÂ count, liver function and alpha-fetoprotein levels in theÂ experimental group were significantly better than those in thecontrol group (P <0.05),Â but no significantÂ difference was foundÂ between the two groups (P<0.05). â‘£ The Karnofsky score of the experimental group wasÂ significantly higher than that of the control group (P<0.05).Â Conclusion:Â Chinese medicine combined with transcatheterÂ arterial chemoembolization in patients with primary liver cancer inÂ the application value is relatively high.
Clinical Efficacy and Safety of Laparoscopic Postope- rative Leuprolide in Treatment of Endometriotic cysts
Authors: Yu Bin , Juan Juan , Su Nita 
Published: July 2018

PurposeÂ To investigate the clinical effect of the use of leuprolide after laparoscopic surgery in patients with endometriosis. Method: Select 220 patients with endometriosis treated in our hospital from January 2015 to June 2016, and randomly divided them into simple group and treatment group, with 110 cases in each group. The simple group did not receive any treatment after laparoscopic surgery. The treatment group received leuprolide after surgery. Compare the treatment effect and safety of the two groups of patients.Â Results The treatment efficiency of the treatment group was significantly better than that of the simple group, P<0.05; and the relapseÂ rateÂ of the treatment group was low, P<0.05. ConclusionÂ The use effect of leuprolide in the treatment of endometriosis patients after laparoscopic surgery is better, with low relapse rate and high safety, and is worthy of clinical promotion.
Diagnostic Value of CYFRA21-1, CA19-9 and SCCAg Detection in Esophageal Cancer
Authors: Du Chunran , Wang Yanming , Hou Shenyan 
Published: July 2018

ObjectivesÂ To investigate the value of serum cytokeratin 19 fragment (CYFRA21-1), carbohydrate anti-gen 19-9 (CA19-9) and squamous cell carcinoma antigen (SCCAg) in the diagnosis of esophageal cancer. MethodsÂ 100Â cases of esophageal cancer (study group) and 50 healthy subjects (control group) were recruited in the study, the serumÂ levels of CYFRA21-1, CA19-9 and SCCAg in these patients were detected. Subgroups analysis was performed in studyÂ group by clinical staging, and the diagnostic value of CYFRA21-1, CA19-9 and SCCAg in detecting esophageal cancerÂ was analyzed by receiver operating characteristic curve (ROC). ResultsÂ The serum levels of CYFRA21-1, CA19-9 andÂ SCCAg in study group were significantly higher than those in control group, and those were significantly lower in patients with stageâ… -â…¡Â disease than those with stage â…¢Â and â…£Â disease, indicating statistically significant difference (P<0.01); the sensitivity of serum CYFRA21-1, CA19-9 and SCCAg in the diagnosis of esophageal cancer was 82.26%, andÂ specificity was 91.33%, Â with positive predictive value being Â 86.14%, and negative predictive value being 89.57%, andÂ AUC value was 0.864, the combined detection was superior to each measure utilized alone, the difference was significantly significant (P<0.05). ConclusionÂ The combined detection of serum CYFRA21-1, CA19-9, and SCCAg can significantly improve the diagnostic sensitivity and specificity in detecting the esophageal cancer.
BioinformaticsAnalysis of the Muscle-invasive Bladder Cancer Subtypes
Authors: Xu Wenbin , Zheng Weiying , Xia Hong , Hua Lin 
Published: July 2018

ObjectiveÂ In order to improve the accuracy in distinguishing subtypes of bladder cancer and to explore its potential therapeutic targets,Â we identify differences between two kinds of bladder cancer subtypes (basal-like and luminal) in molecular mechanism and molecular characteristics based on the bioinformatics analysis. MethodsÂ In this study,Â the RMA (robust multichip averaging) was applied to normalize the mRNA profile which included 22 samples from basal-like subtype and 132 from luminal subtype,Â and the differential expression analysis of genes with top 1000 highest standard deviation was performed. Then,Â the Gene Ontology and KEGG pathway enrichment analysis of differentially expressed genes was performed. In addition,Â the protein-protein interactions networks analysis for the top 100 most significant differentially expressed genes was performed. ResultsÂ A total of 742 differentially expressed genes distinguishing basal-like and luminal subtypes were found,Â of which 405 were up-regulated and 337 genes were down-regulated in basal-like subtype. GO enrichment analysis showed that differentially expressed genes were significantly enriched in the extracellular matrix,Â chemotaxis and inflammatory response. KEGG pathway enrichment analysis showed that the differentially expressed genes were significantly enriched in the pathway of extracellular matrix receptor interaction. The hub proteins we founded in protein-protein interaction networks were LNX1,Â MSN and PPARG. ConclusionÂ In this study,Â the mainly difference of molecular mechanism between basal-like and luminal subtypes are alteration in extracellular matrix region,Â cell chemotaxis and inflammatory response. Genes such as LNX1,Â MSN and PPARG were forecast to play important roles in the classification of bladder carcinoma subtypes.
Reduced Beam Section (RBS) Moment Connections-Analytical Investigation Using Finite Element Method
Authors: Sofias Christos , Tzourmakliotou Dimitra 
Published: July 2018

Reduced Beam Section (RBS) moment resisting connections are among the most economical and practical rigid steel connections developed in the aftermath of the 1994 Northridge and the 1995 Kobe earthquakes. Although the RBS connection effectiveness was widely investigated using US design and construction practices, only limited data exist from European research. Recommendations of RBS applications in steel frames were prescribed in EC8, Part3. However the reliability of these recommendations is under consideration due to above mentioned poor existing data. This paper examines numerous different contours of radius cut-out (Group A) and provides recommendations for the design and detailing of radius cut Reduced Beam Section (RBS) moment connections. Furthermore, it examines and compares different beam cross sections of European steel profiles (Group B) while the sizing of the RBS cut is kept at a constant ratio. Analytical approach was conducted investigating the adopted by EC8, Part 3 key parameters for the design. The main objective of the applied RBS geometry is to protect the connection and its components (endplate, column flange, bolts, welds) from either plastification or failure. Although the computational cost for optimization with ABAQUS is very large, the results of this study ensures on one hand that the performances of the structural parts can be effectively improved by shape optimization and an the other hand that adjustment in the geometry of the radius cut is needed for safe application to European profiles.
The Impact of Context-Based Capabilities on the Type of Communication of Spaces
Authors: Khakpour Mojgan , Daghighi Masoule Guilda , Amirnejad Mojdehi Mehrdad 
Published: July 2018

Perceiving an architectural work requires a comprehensive understanding of its context, since the context has a direct impact on both the body and the activities. This recognition can be examined from two aspects: the study of natural and geographical conditions and human-based conditions which include the symbolic, religious-cultural, historical, social, and economic values. What has been considered through this article was the effect of these factors on the type of communication between the spaces. Due to the climate and cultural characteristics across Guilan province, it seems that the spaces from their public realm- that is from the neighbourhood spaces to their most exclusive parts- include rooms and closed spaces that have such continuity which was created by the elements of the boundary between these spaces. These elements link the spaces together and lead to a hierarchy of activities. The research question is whether the relationship between spaces and spatial continuity in traditional architecture of Rasht is influenced by the capabilities of the context or not? This is a descriptive-analytical research, which used a qualitative research method. Data collection was carried out by using desk research method and field observations. The data was analysed through content analysis and independent of numerical documentation within an analogy process. With respect to the effect of filed capabilities on the traditional architecture in Rasht city, first a sample of buildings was selected and the physical elements contributing to continuity of the space have been studied. Then, the effect of the context-based capabilities on them was considered. It was found that these capabilities contributed to formation of the physical elements and behavioural patterns which itself can affect the type of relationship between space and its continuity within old urban tissues of Rasht, including the sensory continuity and the physical continuity between the spaces.
Effects of Near Fault and Far Fault Ground Motions on Nonlinear Dynamic Response and Seismic Improvement of Bridges
Authors: Hajali Mohammad , Jalali Abdolrahim , Maleki Ahmad 
Published: July 2018

In this study, the dynamic response of bridges to earthquakes near and far from the fault has been investigated. With respect to available data and showing the effects of key factors and variables, we have examined the bridge’s performance. Modeling a two-span concrete bridge in CSI Bridge software and ability of this bridge under strong ground motion to near and far from fault has been investigated. Nonlinear dynamic analysis of time history includes seven records of past earthquakes on models and it was observed that the amount of displacement in the near faults is much greater than the distances far from faults. Bridges designed by seismic separators provide an acceptable response to a far from fault. This means that in bridges using seismic separators, compared to bridges without seismic separators, Acceleration rate on deck, base shearing and the relative displacement of the deck are decrease. This issue is not seen in the response of the bridges to the near faults. By investigating earthquakes near faults, it was observed that near-fault earthquakes exhibit more displacements than faults that are far from faults. These conditions can make seismic separators critical, so to prevent this conditions FDGM should be used to correct the response of these bridges. Based on these results, it can be said that the displacement near faults with forward directivity ground motion is greater than far from faults. So that by reducing the distance from the faults, the maximum value of the shearing and displacement of the deck will be greater.
Global Diagnostic on Groundwater Governance
Authors: Rubio Marina 
Published: July 2018

Five international organisations cooperated in the project ‘Groundwater Governance: A Global Framework for Action’ (2011-2016): Global Environment Fund (GEF), Food and Agriculture Organization of the United Nations (FAO), United Nations Economic, Social and Cultural Organization International Hydrological Program (UNESCO IHP), International Association of Hydrogeologists (IAH) and World Bank.
The project included a wide range of activities aiming to take stock of groundwater governance conditions and practices around the world and to enable diagnostic analysis at different spatial scales on groundwater governance. Five Regional Consultation Meetings were conducted in different parts of the world, with the aim to collect as much information as possible on groundwater governance in different regions and countries, and to capture the related perceptions and opinions of the more than five hundred participants. On top of this, five regional diagnostic reports on groundwater were prepared by knowledgeable professionals from each of these regions. The present Global Diagnostic on Groundwater Governance builds on all these activities and produced outputs, in particular on the five regional diagnostics and the reports on the Consultation Meetings.

Governance
Groundwater
Human Water Stress in Transboundary River Basins
Authors: Carvalho-Resende Tales 
Published: July 2018

The Human Water Stress indicator deals with the quantity of water available per person per year relative to the internal and upstream area water supplies, on the premise that the less water available per person, the greater the impact on human development and well-being, and the less water there is available for other sectors.
For more information, visit: http://twap-rivers.org/

Basin
Stress
Supply
Surface water
Transboundary
Area equipped for irrigation with water from non-conventional water sources
Authors: Carvalho-Resende Tales 
Published: July 2018

Area equipped for irrigation with water from non-conventional water sources as a percentage of total area equipped for irrigation. The statistics with a reference year closest to year 2005 were selected for this version 5 of the Global Map of Irrigation Areas.
For mor information, visit: http://www.fao.org/nr/water/aquastat/irrigationmap/index10.stm

Agriculture
Irrigation
Area equipped for irrigation with surface water
Authors: Carvalho-Resende Tales 
Published: July 2018

Area equipped for irrigation with surface water as percentage of area equipped for irrigation. The statistics with a reference year closest to year 2005 were selected for this version 5 of the Global Map of Irrigation Areas.
For mor information, visit: http://www.fao.org/nr/water/aquastat/irrigationmap/index10.stm

Agriculture
Irrigation
Major River and Lake Basins of the World
Authors: Carvalho-Resende Tales 
Published: July 2018

The dataset comprises the GIS layer of 405 major river and lake basins of the world.
Data was collected within the framework of the BGR-UNESCO "World-wide Hydrogeological Mapping and Assessment Programme" (WHYMAP): www.whymap.org

Basin
Surface water
Transboundary
Reviews
Authors: Looser Devoney , Prunean Alexandra , Owen David 
Published: July 2018

Juliet McMaster's Jane Austen, Young Author (Ashgate [now marketed by Routledge], 2016), reviewed by Devoney Looser; Ethel Turner's Tales from the Parthenon and That Young Rebel, edited by Pamela Nutt with others (Juvenilia Press, 2014 and 2015), reviewed by Alexandra Prunean; Laurie Langbauer's The Juvenile Tradition: Young Writers and Prolepsis, 1750-1835 (Oxford UP, 2016), reviewed by David Owen.
Escenario para la transmisión de streaming adaptativo DASH-WebM
Authors: Ortiz T. Duvernei , Chanchí G. Gabriel E. , Arciniegas H. José L. , Durán D. Diego F. , Campo M. Wilmar Y. 
Published: July 2018

Tradicionalmente el videostreaming ha sido soportado por los protocolos RTP y RTSP, de modo que el servidor gestiona una sesión diferente para cada cliente y coordina la entrega de paquetes. Actualmente el estándar de streaming adaptativo DASH ofrece otro enfoque a través de HTTP, de tal forma que el cliente extrae los datos del servidor, sin mantener el estado de la sesión. Así, se tiene como ventajas el pleno uso de la infraestructura de Internet y la adaptación del contenido multimedia al ancho de banda de la red. A pesar de lo anterior, el proceso de generación y distribución de contenidos multimedia DASH, requiere la ejecución secuencial de tareas de codificación, segmentación, creación del descriptor MPD y reproducción del contenido DASH. Para el caso de los contenidos multimedia WebM, las anteriores tareas son realizadas separadamente por un conjunto de herramientas libres, por lo que el proceso de generación del contenido DASH no es automático. En este artículo se propone un escenario de transmisión para streaming adaptativo DASH, cuyo principal componente es la herramienta DASHWebMConverter, la cual se encarga de automatizar el proceso de generación de contenidos DASH WebM. Adicionalmente, se presenta la evaluación del escenario de streaming adaptativo, mediante pruebas de seguimiento de ancho de banda y pruebas de consumo de memoria sobre los principales componentes del escenario.