bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of long-term dynamics of circulatory system morbidity in population of Perm and Perm Krai
Authors: Kasatov A. V. , Stepnov S. M. 
Published: June 2019

Aim. To analyze a long-term dynamics of the primary morbidity of circulatory system in the population of Perm and Perm Krai.
Materials and methods. The primary circulatory system morbidity per 1000 of the population of Perm Krai and Perm was analyzed under the materials of Perm Regional Medical Information-Analytical Center. Statistical processing of the data was performed using Microsoft Excel 2016.
Results. Over the period from 2007 to 2017, there was established a growth of the level of primary circulatory system morbidity as a whole and ischemic heart disease in particular among the population of Perm Krai and Perm. Morbidity rate was essentially higher in the inhabitants of Perm Krai but annual gain rate – more significant in the urban population that is explained by availability and quality of medical care and social factors. The growth of the level of primary diseases, characterized by increased arterial pressure, is insignificant during this period of observation. The average annual increase was 1.54 % in the inhabitants of Perm and 0.53 in Perm Krai.
Conclusions. The level of primarily detected circulatory system diseases in the population of Perm Krai and Perm essentially raised for 11 years of observation. Primary IHD morbidity indices as well as average annual rate of their growth is significantly higher than the analogous indices of diseases, characterized by increase in arterial pressure.
Safety of using the preparation “Licopid®” in opinion of experts in various specialities
Authors: Krasheninnikov A. E. , Matveev A. V. , Andronova T. M. , Guryanova S. V. , Shilova N. V. , Kozlov I. G. 
Published: June 2019

Aim. To study the safety of the preparation “Licopid®” using the data, obtained with the method of questioning of doctors of various specialities. The reactant of “Licopid®” tablets is glucoseminylmuramildipeptide – a synthetic analogue of the structural fragment of bacterial cells membrane (peptidoglycan), which is an activator of congenital and acquired immunity;it strengthens the defense of the body from viral, bacterial and fungal infections; it has an adjuvant effect in development of immunological reactions.
Materials and methods. The object of this study were the answers of 2315 specialists to the questions of surveys regarding the safety of using immunomodulator“Licopid®” in their practical activity. The regions, involved into the survey were the following cities: Moscow, Kazan, Krasnodar, Ekaterinburg, St. Petersburg, Chelyabinsk, Novosibirsk, Perm, Samara and Voronezh as well as Krasnodar Krai. Processing of the results was fulfilled with the methods of descriptive statistics; the obtained data were compared with the method based on calculation of chi-square criterion.
Results. The analyzed results showed that 962 respondents (41.5 %) indicated the fact of revealing undesirable reactions (UR) of the preparation “Licopid®” in their own practice. It was noted by them that all undesirable reactions were not severe and predicted, i.e. they were indicated in the instruction for medical use of “Licopid®” 1 mg and 10 mg.
Conclusions. While conducting questioning, the authors revealed statistically significant differences in the structure of respondents’ answers depending on the region of residence and medical speciality. At the same time, for all UR, indicated in instruction, subjectively estimated occurrence rate of reactions coincided with that, declared upon registration, except myalgias and arthralgias, which were noted by doctors much rarely.
Physiologo-hygienic grounding for using physical properties of natural potassium salts to increase duration of chronic cardiovascular and respiratory diseases remission
Authors: Ryazanova E. A. , Barannikov V. G. , Kirichenko L. V. , Sidorova D. A. 
Published: June 2019

Aim. To implement physiologo-hygienic studies regarding the period of remission of chronic diseases after sylvinite therapy for introducing them into medical practice.
Materials and methods. Hygienic assessment of internal environment conditions of modern saline devices taking into account their constructive features was carried out. Physiological functions of the main systems of an organism were analyzed in patients, who received the course of mineral prophylaxis.
Results. In modern sylvinite constructions there is formed a favorable environment, rendering a positive preventive influence on patients’ organism.
Conclusions. Physical properties of natural potassium salts, used to prevent chronic diseases, contribute to prolongation of remission period.
Selection of Marine Security Policy using Fuzzy-AHP TOPSIS Hybrid Approach
Authors: Hozairi Hozairi , Buhari Buhari , Lumaksono Heru , Tukan Marcus 
Published: June 2019

The research was focused on the integration of Fuzzy set theory with Analytic Hierarchy Process (AHP) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) to choose the optimum maritime security policy to achieve Indonesia recognition as the world's maritime axis. The method used is AHP with fuzzy based enhancement. Here, the weight of each criterion is calculated to overcome the criticism of the scale of unbalanced rating, uncertainty, and inaccuracy in the pairwise of comparison process. The best recommendation for Indonesian maritime policies is multi task single agency which is greatly infuenced by several factors such as technology, regulations, infrastructure, economic, politic, and socio-culture. The finding shows that the hybrid approach is able to produce the best recommendation for Indonesian maritime security policy.
Pengaruh Ekstrak Etanol 90% terhadap Kadar Malondialdehid (MDA) dan Superoksida Dismutase (SOD) Mencit Tikus yang Dipapar Asap Rokok
Authors: Prayitno Sutrisno Adi , Kusnadi Joni , Muritni Erni Sofia 
Published: June 2019

<pre>Cigarette smoke is a source of free radicals which cause human body organs damage when it is exposed. Cigarette smoke as a medium that causes oxidative stress that has the potential to cause oxidative damage. In addition, cigarette smoke also has potency to reduce SOD (Superoxide dismutase) levels and increase MDA (Malondialdehyde) levels especially in lung tissue. To control or prevent the presence of free radicals in the body, antioxidant compounds are needed by the body. The purpose of this research is to know the effect of the extract of red betle on SOD and MDA content of mice exposed to cigarette smoke. Red betle was extracted by maceration using ethanol. The exposed mice were treated with red betle extract for 14 days. Lung tissue of the mice was analyzed SOD and MDA conentrations. The results showed that SOD levels tend to increase and decrease MDA levels in mice test animals exposed to cigarette smoke. The optimal dose to decrease MDA levels and increase SOD is 230.4 mg/g weight/day. Histopatology result showed there is different figure of lung tissue (alveoli) before and after red betle extract treatment.</pre><p class="BodyAbstract"> </p><p class="BodyAbstract">Asap rokok adalah sumber radikal bebas yang dapat mengakibatkan rusaknya organ dalam tubuh manusia apabila terpapar. Asap rokok sebagai media penyebab terjadinya stress oksidatif yang berpotensi menyebabkan kerusakan oksidatif. Selain itu, asap rokok juga berpotensi dalam menurukan kadar SOD (Superoksida Dismutase) dan meningkatkan kadar MDA (Malondialdehida) terutama pada jaringan paru. Untuk mengendalikan atau mencegah adanya radikal bebas ke dalam tubuh maka senyawa antioksidan dibutuhkan oleh tubuh. Tujuan penelitian adalah adalah mengetahui pengaruh ekstrak etanol daun sirih merah terhadap kadar SOD dan MDA mencit yang dipapar asap rokok. Daun sirih merah diekstrak menggunakan metode maserasi. Mencit yang telah dipapar asap rokok diberi perlakuan ekstrak selama 14 hari. Jaringan paru-paru dianalisis kadar MDA dan SOD. Hasil penelitian menunjukan kadar SOD cenderung mengalami peningkatan dan kadar MDA mengalami penurunan pada hewan uji mencit yang dipapar asap rokok. Dosis yang paling optimal untuk menurunkan kadar MDA dan menaikan SOD adalah dosis 230,4 mg/g bb/hari. Hasil histopatologi menunjukkan terdapat perbedaan gambaran jaringan paru-paru (alveoli) sebelum dan setelah perlakuan ekstrak.</p><p class="BodyAbstract"> </p>
Aktivitas Antimalaria Ekstrak Kasar Etanol dan Fraksi n-Heksana Rumput Bambu (Lophatherum gracile B.) secara in Vitro
Authors: Wulandari Ella , Yuliani Dewi , Hayati Elok Kamilah , Muti'ah Roihatul 
Published: June 2019

<p>Malaria is a disease caused by infectious parasite <em>Plasmodium falciparum</em> and can be transmitted through mosquito bite. The aim of this research was to study antimalarial activity <em>in vitro</em> on crude ethanol extract and n-hexane fraction of bamboo grass (<em>Lophatherum gracile</em> B.). Extraction was carried out by ethanol 80% solvent and fractionation was conducted by n-hexane. Determination of antimalarial activity was subjected to <em>P. falciparum</em> strain 3D7. According to phytochemical test, crude ethanol extract contained tannin and terpenoid, whilst n-hexane fraction contained tannin and steroid. The capability of crude ethanol extract and n-hexane fraction to inhibit <em>P. falciparum</em> was represented by IC<sub>50</sub> value. The value of both samples respectively was 12.49 and 61.49 µg/mL. Identification based on LC-MS (liquid chromatography-mass spectrometry), n-hexane fraction shown the presence of tannin and steroid compounds.</p><p> </p><p>Malaria merupakan penyakit yang disebabkan oleh infeksi parasit <em>Plasmodium falciparum</em> yang dapat ditularkan melalui gigitan nyamuk. Penelitian ini bertujuan untuk mengetahui aktivitas antimalaria secara <em>in vitro</em> pada ekstrak kasar etanol dan fraksi n-heksana rumput bambu (<em>L</em><em>ophat</em><em>h</em><em>erum gracile </em>B.). Proses ekstraksi dilakukan dengan pelarut etanol 80% dan fraksinasi dengan n-heksana. Uji aktivitas antimalaria dilakukan pada parasit <em>P. falciparum </em><em>strain</em> 3D7<em>.</em> Hasil uji fitokimia menunjukkan ekstrak etanol mengandung tanin dan terpenoid, sedangkan fraksi n-heksana mengandung tanin dan steroid. Kemampuan ekstrak etanol dan fraksi n-heksana dalam menghambat parasit <em>P. falciparum</em> menghasilkan nilai IC<sub>50</sub> masing-masing sebesar 12,49 dan 61,49 µg/mL. Identifikasi senyawa dengan KC-SM (kromatografi cair-spektrometri massa) pada fraksi n-heksana menunjukkan adanya senyawa tanin dan steroid.</p>
Perbandingan Butiran Kitosan dengan Pengikat Silang Epiklorohidrin (ECH) dan Glutaraldehid (GLA): Karakterisasi dan Kemampuan Adsorpsi Timbal (Pb)
Authors: Madjid Armeida Dwi Ridhowati , Nitsae Merpiseldin , Sabarudin Akhmad 
Published: June 2019

<table width="661" border="1" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="408"><p class="BodyAbstract">Chitosan was an abundantly available source but it has a drawback which unstable in acid or base. So, it must be added with a crosslinker. In this article, we would compare the using of 2 crosslinkers, glutaraldehyde (GLA) and epichlorohydrin (ECH). Chitosan was formed as bead using tripolyphosphate (TPP). Chitosan beads crosslinked with GLA became browny beads and chitosan beads crosslinked with ECH became pearly white. IR characterization showed peaks in 1640 and 1540 cm<sup>-1</sup> represent phosphate contained TPP. There is no significant or unique peak differ GLA chitosan bead from ECH chitosan bead. Adsorption capacity of lead (Pb) in ECH chitosan bead was higher than in GLA chitosan bead. Morphology in SEM characterization exhibited a crinkle GLA chitosan bead then ECH chitosan bead.</p><p class="BodyAbstract"> </p><p class="BodyAbstract">Kitosan merupakan polimer alam dengan ketersediaan yang meruah tetapi memiliki kelemahan yaitu kurang stabil dalam asam maupun basa sehingga diperlukan pengikat silang. Dalam artikel ini akan dibandingkan dengan penggunaan 2 agen pengikatsilang yang dapat mengatasi permasalahan tersebut yaitu epiklorohidrin (ECH) dan glutaraldehid (GLA). Untuk pembuatan butiran kitosan digunakan tripolyphosphate (TPP). Setelah menjadi butiran kitosan diikatsilangkan dengan GLA menjadi butiran kitosan yang berwarna kecoklatan dan diikatsilangkan dengan ECH menjadi butiran kitosan bening. Karakterisasi spektrofotometri Infra Merah menunjukkan puncak pada daerah 1640 dan 1540 cm<sup>-1</sup> yang merupakan serapan khas dari tripolyphospate sedangkan tidak nampak perbedaan puncak spektra yang signifikan dari butiran kitosan GLA maupun ECH. Kemampuan adsorpsi butiran logam timbal (Pb) butiran kitosan ECH lebih tinggi jika dibandingkan dengan butiran kitosan GLA. Morfologi butiran kitosan dianalisis menggunakan Scanning Electron Morphology (SEM) dan menunjukkan bahwa morfologi untuk butiran GLA memiliki morfologi yang lebih berkerut jika dibandingkan dengan butiran ECH.</p></td></tr></tbody></table>
Variasi Diameter Kolom dan Rasio Sampel-Silika pada Isolasi Steroid dan Triterpenoid Alga Merah Eucheuma cottonii dengan Kromatografi Kolom Basah
Authors: Fasya Ahmad Ghanaim , Tyas Ariska Purwaning , Mubarokah Fitroh Annasaul , NIngsih Rachmawati , Madjid Armeida D. R. 
Published: June 2019

<p>Optimizing steroid and triterpenes isolation from red algae <em>Eucheuma cottonii</em> was done using column chromatography by varying of column diameter (1, 1.5 and 2 cm) and a ratio of sample : silica (1:50, 1:100, and 1:150). Active compound of <em>E. cottonii</em> was extracted by maceration with methanol. Then, the extract was hydrolyzed using HCl 2 N and partitioned with petroleum ether. The extract after partitioned was separated using wet column chromatography. The result of separation was monitored using analytical thin layer chromatography (Analytical TLC) and identified using FTIR. The best separation was aimed using diameter column 1 cm and a ratio of sample : silica 1:150. Based on FTIR analysis, the steroid from extract had a functional group –OH, –C–H, C=O, -C(CH<sub>3</sub>)<sub>2</sub>, and C-OH alcohol and the triterpenoid from extract had a functional group –OH, C–H, C=O, C=C, -C(CH<sub>3</sub>)<sub>2</sub> and C-OH alcohol.</p><p>Keywords: <em>E. cottonii</em>, column chromatography, steroid, triterpenoid, column size, sample : gel silica ratio</p><p> </p><p> </p><p><span>Optimasi isolasi senyawa steroid dan triterpenoid dalam alga merah <em>Euchema cottonii</em> telah dilakukan menggunakan kromatografi kolom dengan variasi diameter kolom (1; 1,5; dan 2 cm) dan rasio sampel : silika (1:50; 1:100; dan 1:150). Ekstraksi senyawa aktif pada <em>E. cottonii</em> dilakukan dengan maserasi menggunakan pelarut metanol. Ekstrak pekat metanol dihidrolisis menggunakan HCl 2 N dan dipartisi dengan petroleum eter. Hasil pemisahan dimonitoring menggunakan KLTA dan diidentifikasi menggunakan FTIR. Hasil penelitian menunjukkan pemisahan kromatografi kolom terbaik diperoleh dengan variasi diameter 1 cm dan variasi rasion sampel : silika 1:150. Hasil analisis senyawa steroid memberikan informasi gugus –OH, –C–H, C=O, -C(CH<sub>3</sub>)<sub>2</sub>, dan C-OH alkohol, sedangkan senyawa triterpenoid memberikan informasi gugus –OH, –C–H, C=O, C=C, -C(CH<sub>3</sub>)<sub>2</sub> dan C-OH alkohol.</span></p><p><span><span>Kata Kunci: <em>E. cottonii</em>, kromatografi kolom, steroid, triterpenoid, ukuran kolom, rasio sampel : silika gel</span></span></p>
Synthesis of Goethite (α-FeOOH) Pigment by Precipitation Method from Iron Lathe Waste
Authors: Khoiroh Lilik Miftahul , Nuraini Elysia Dwi , Aini Nur 
Published: June 2019

<p>Lathe waste contains high iron content potential to be further processed into goethite pigment. The purpose of the research was to determine the effect of synthesis temperature on the structure, colour values, and morphology of goethite pigment. The synthesis was conducted with temperature variations of 60, 70, 80and 90°C. The XRD diffraction pattern shows that crystal structure of the product of all synthesis temperatures are goethite (α-Fe-OOH) with orthorhombic structure. The crystal size of the pigment ranges between 11.17 – 12.32 nm. Colour value analysis shows that product of 70°C synthesis temperature exhibits the highest lightness value about 40.5. Based on SEM-EDX imaging, the morphology of the samples is not uniform and forming agglomerates. Traces of impurities were detected, such as C and Na.</p><p> </p><p>Keywords: Iron lathe waste, goethite, temperature, precipitation</p>
PEMBELAJARAN FISIKA BERBASIS MASALAH MELALUI METODE EKSPERIMEN DAN DEMONSTRASI DITINJAU DARI KEMAMPUAN MENGGUNAKAN ALAT UKUR DAN SIKAP ILMIAH SISWA
Authors: Al IIdrus Kadir 
Published: June 2019

Tujuan penelitian ini adalah untuk mengetahui: (1) pengaruh penggunaan metode pembelajaran eksperimen dan demonstrasi terhadap prestasi belajar, (2) pengaruh kemampuan menggunakan alat ukur terhadap prestasi belajar, (3) pengaruh sikap ilmiah terhadap prestasi belajar, (4) interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur terhadap prestasi belajar, (5) interaksi antara metode pembelajaran dengan sikap ilmiah terhadap prestasi belajar, (6) interaksi antara kemampuan menggunakan alat ukur dengan sikap ilmiah terhadap prestasi belajar, (7) interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur dan sikap ilmiah terhadap prestasi belajar.
Penelitian ini menggunakan metode eksperimental (experimental research). Populasi penelitian adalah seluruh siswa kelas XI program IPA SMA Negeri 2 Mataram tahun pelajaran 2017/2018, sebanyak 8 kelas. Sampel penelitian ditentukan secara acak dengan teknik cluster random sampling sebanyak dua kelas. Kelas eksperimen 1 dengan metode eksperimen dan kelas eksperimen 2 dengan metode demonstrasi. Teknik pengumpulan data menggunakan metode tes untuk mendapatkan data prestasi belajar kognitif dan kemampuan menggunakan alat ukur, sedangkan metode angket untuk mendapatkan informasi sikap ilmiah dan prestasi belajar afektif. Uji hipotesis penelitian menggunakan anava tiga jalan dengan desain faktorial 2x2x2 dan frekuensi sel tidak sama.
Dari hasil penelitian dapat disimpulkan bahwa: (1) Tidak ada pengaruh penggunaan metode pembelajaran eksperimen dan demonstrasi terhadap prestasi kognitif (p-value = 0,151) dan afektif (p-value = 0,368). (2) Tidak ada pengaruh kemampuan menggunakan alat ukur terhadap prestasi kognitif (p-value = 0,593) dan afektif (p-value = 726). (3) Tidak ada pengaruh sikap ilmiah terhadap prestasi kognitif (p-value = 0,399) dan afektif (p-value = 0,084). (4) Tidak ada interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur terhadap prestasi kognitif (p-value = 0,832). (5) Tidak ada interaksi antara metode pembelajaran dengan sikap ilmiah terhadap prestasi kognitif (p-value = 0,839). (6) Tidak ada interaksi antara kemampuan menggunakan alat ukur dengan sikap ilmiah terhadap prestasi kognitif (p-value = 318). (7) Ada interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur dan sikap ilmiah terhadap prestasi kognitif (p-value = 0,029).
OPTIMIZING THE DEVELOPMENT OF ISLAMIC FINANCIAL INSTITUTIONS IN WEST SUMATRA: ROLE OF LOCAL WISDOM ANALYSIS OF TUNGKU TIGO SAJARANGAN
Authors: Mursal Mursal , Cahya Bayu Tri 
Published: June 2019

<p>This study aims to analyze how the convergence of <em>Tungku Tigo Sajarangan</em> in sharia economic development through Islamic Financial Institutions (IFI), and then constructs how the concept of sharia economic development is based on the local wisdom of <em>Tungku Tigo Sajarangan</em> in developing IFI.</p><p>This research is a qualitative research with a sociological approach. The source of this research data was obtained from the informants who were considered to have information about the focus of this study, namely IFI managers and other informants who were considered to support this research.</p><p>Listening to the data obtained, this study concludes: First, the <em>Tungku Tigo Sajarangan</em> has not given an optimal role in the development of IFI in West Sumatra. Second, optimizing the role of <em>Tungku Tigo Sajarangan</em> in the development of IFI can be strengthened by increasing the synergy with TTS internal and related parties to perform socialization of sharia economic norms in massive, identification of syar'i transaction products, and internalization of <em>adat basandi syarak, syarak basandi kitabullah</em><em>. </em></p><p><strong><em> </em></strong></p>
METODE DONGENG DAN PEMBENTUKAN JIWA RELIGIUS ANAK PENYANDANG TUNA GRAHITA RINGAN
Authors: Isnawati Zakiyah 
Published: June 2019

Kemajuan teknologi, pengetahuan dan pergerakan zaman menuntut kita untuk terus melakukan inovasi pembelajaran. Perbedaan generasi mempengaruhi perbedaan model, pendekatan dan metode pembelajaran serta gaya belajar siswa. Sebagai seorang guru, kita harus menyesuaikan gaya belajar siswa sehingga pembelajaran bisa berhasil mencapai tujuan. Jika kita tidak melakukan penyesuaian, maka pembelajaran tidak akan berhasil dan pendidikan akan tertinggal jauh dari perkembangan zaman
Control of Electrical and Optical Parameters of Humidity Sensors Active Elements Based on Tin Oxides Films with Variable Composition
Authors: Adamchuck D. V. , Ksenevich V. K. 
Published: June 2019

The aim of this work is development of technique for synthesis of tin oxides films with various stoichiometric composition, characterized by high electrical conductivity and light transmittance in the UV and visible range of the electromagnetic spectrum, for their further application as humidity and gas sensors, as well as electrodes for electro-and photocatalytic converters.Nonstoichiometric SnO/SnO2 /SnO2−δ films were synthesized by reactive magnetron sputtering of tin onto glass substrates in argon plasma with oxygen addition and with subsequent thermal oxidation of the formed layers in air. To change the structural, optical, and electrical properties of the films and to find out the optimal synthesis parameters, the oxygen content during the deposition process and the annealing temperature in air were varied in the range of 0–2 vol. % and of 200–450 °C, respectively. The characterization of the films was carried out using a 4-probe method for measuring the electrical resistance, X-ray diffraction, and optical spectroscopy of light transmission.As a result of a comprehensive analysis of the structural, optical and electrical properties of the films, it was found that the optimal synthesis parameters to obtain the most transparent and conductive coatings promising for use as humidity, gas sensors and in photovoltaic devices are the following: oxygen content in argon plasma during sputtering process is ≈ 0,8–1,2 vol. %, the annealing temperature in air is ≈ 350–375 °C. In this case a polycrystalline film with high electrical conductivity and high transmittance in the visible and UV regions of the electromagnetic spectrum with prevailing of tin dioxide phase with structural defects (oxygen vacancies) is formed.