bluuebunny/crossref_metadata_2025_split huggingface dataset:
MRI-guided neurolysis for the treatment of chronic refractory knee pain: a case report
Authors: Marka Alexander W. , Strenzke Maximillian , Weiss Kilian , Karampinos Dimitrios C. , Woertler Klaus , Herbort Mirco , Befrui Nima , Finck Tom 
Published: November 2024

AbstractChronic refractory pain poses a significant challenge in knee joint pathologies, especially after exhaustion of conservative, arthroscopic, and endoprosthetic therapy options. This case report illustrates an innovative approach using MRI-assisted chemical neurolysis of a genicular nerve to manage persistent knee pain after arthroscopy. A 62-year-old male patient with chronic refractory knee pain, primarily localized at the inferomedial part of the knee, underwent high-resolution MRI to visualize the genicular nerves. This allowed for targeted ethanol-based neurolysis of the inferomedial genicular nerve. Following the procedure, the patient experienced substantial pain reduction for the follow-up duration of 4 months. The successful use of MRI-assisted chemical neurolysis offers a promising alternative treatment for patients with refractory knee pain, providing long-lasting pain relief without major side effects. This technique has the potential to improve the quality of life for patients suffering from chronic knee pain While these initial results are encouraging, it is important to note that further research, including both short-term and long-term studies, as well as randomized controlled trials, is warranted to establish the efficacy and safety of this treatment method in broader populations before it can be considered for routine incorporation into pain management practices.
Novel nerve regeneration assessment method using adult zebrafish with crush spinal cord injury
Authors: Motohashi Hiroaki , Sugita Satoshi , Hosokawa Yoshito , Hasumura Takahiro , Meguro Shinichi , Ota Noriyasu , Minegishi Yoshihiko 
Published: November 2024

AbstractZebrafish (Danio rerio), an alternative to rodents, are widely used in neurological, genetic, and toxicology research. The zebrafish larval spinal cord injury model has been used in neural mechanistic analyses owing to its high regenerative capacity and throughput; however, it also had several limitations in imitating rodents. Therefore, we investigated the use of adult zebrafish as an alternative model to rodents for evaluating nerve regeneration. Here, we established a novel spinal cord regeneration evaluation method, which was based on the maximum swimming speed of adult zebrafish in a custom-built hydrodynamic-based aquarium. The spinal cords of adult male zebrafish were crushed using forceps, and maximum swimming speed and histological spinal cord regeneration were evaluated. Spinal cord-injured zebrafish showed a significant decline in motor function, followed by recovery at 3 weeks postoperatively, accompanied by histological regeneration. Spinal cord regeneration can be indirectly assessed by monitoring maximum swimming speed. They were also fed a diet containing fig extract, which can promote peripheral nerve regeneration; they were fed daily starting 1 week before the operation. Maximum swimming speed was measured time-dependently until 3 weeks postoperatively. Fig-consuming fish showed improved recovery of maximum swimming speed compared to the controls, which was consistent with the histological analysis. In summary, we established a spinal cord regeneration assessment system using adult zebrafish in a customized aquarium, which enables researchers to evaluate spinal cord regeneration in adult zebrafish similar to that of rodent experiments, contributing to faster and easier screening of neuroregenerative technology.
Ocular involvement of oak processionary caterpillar hairs: Clinical outcome up to one year
Authors: Leclaire Martin Dominik , Vietmeier Friederike Elisabeth , Treder Maximilian , Eter Nicole , Baydoun Lamis 
Published: November 2024

Abstract
Purpose
To evaluate a consecutive series of patients that presented with ocular findings after contact with the oak processionary caterpillar (OPC) during an epidemic reproduction of the OPC in Germany in 2019 and to assess the 1-year outcome of those eyes with persisting OPC hairs in the cornea.

Methods
Retrospective analysis of 11 eyes (11 patients) that presented in June/July 2019 with acute ocular symptoms after outdoor activity or caterpillar nest removal. Evaluation of patients charts and slit-lamp images up to one year. Assessment of the incidence of patients with OPC-associated ocular complaints in the subsequent years (2020–2023).

Results
All patients had conjunctival injection, foreign body sensation, pain, itching and/or burning sensation. In 9/11 eyes, multiple caterpillar hairs could be detected in the superficial and deeper cornea. Hair removal was attempted in 8/9 eyes; in one eye hair removal was impossible due to its deep stromal location (lost-to-follow-up). Entire hair removal was successful in 2/9 eyes, hence, six eyes with persisting hairs within the cornea were followed. Stromal haze developed adjacent to the hairs in all eyes and individual hairs disappeared (n = 4) and/or showed migration within the cornea (n = 3). Until 2023, the number of patients with OPC-associated ocular complaints decreased continuously.

Conclusions
Ophthalmologists should be aware of the possibility of caterpillar hairs in patients with acute eye symptoms after outdoor acitivities, especially in early summer; the incidence may fluctuate, though. Hair removal is recommended to avoid possible intraocular migration, still residing hairs did not cause any serious long-term complications in our cohort.

Key Messages
What is known

Within the late spring and early summer season, mass reproduction of the oak processionary carterpillar (OPC) can lead to an increased number of patients with OPC-related eye complaints (pain, itching and burning sensation) caused by OPC hairs within a very short period of time.

Within that season, people should be (more) actively sensitized to avoid trees with OPC hairs, take precautions and avoid eye rubing when having complaints

What is new

Complete surgical removal of the hairs can be difficult and is often unsuccessful due to their tiny size and often stromal location most possibly resulting from eye rubbing

In the longer-term, residing hairs have shown to develop haze adjacent to the hair, migrate within the cornea or disappear/resolve. Since this may go along with an inflammatory reaction, long-term follow-up and topical steroids may be useful
RNF213 p.Arg4810Lys Variant Is Associated with Higher Stenosis Progression in Asymptomatic Intracranial Artery Stenosis
Authors: Dofuku Shogo , Miyawaki Satoru , Imai Hideaki , Shimizu Masahiro , Hongo Hiroki , Shinya Yuki , Ohara Kenta , Teranishi Yu , Ono Hideaki , Nakatomi Hirofumi , Teraoka Akira , Saito Nobuhito 
Published: November 2024

AbstractIntracranial artery stenosis (ICAS) is a significant contributor to ischemic stroke, with the RNF213 p.Arg4810Lys variant identified as a related genetic factor. We explored the clinical outcomes of the RNF213 genotype in patients with asymptomatic ICAS. Between November 2011 and March 2019, 139 patients with asymptomatic ICAS were enrolled in this study. Genotyping for RNF213 p.Arg4810Lys was performed using Sanger sequencing. A comprehensive analysis was conducted to compare the RNF213 genotype with background characteristics and clinical outcomes such as ipsilateral ischemic cerebrovascular events and stenosis progression. RNF213 p.Arg4810Lys was found in 25% of cases, revealing distinct clinical features between carriers and non-carriers. The incidence of ipsilateral ischemic cerebrovascular events was 4.3% (6/139 cases), and stenosis progression was observed in 13% (18/139 cases) during a mean follow-up period of 58 months. Stenosis progression rates were notably higher in the RNF213 variant group (25.7%; 9/35 cases) than in the RNF213 wild-type group (8.7%; 9/104 cases). Cumulative stenosis progression rate was significantly higher in the RNF213 variant group than in the RNF213 wild-type group (log-rank test, P = 0.0004). Multivariate Cox regression analysis indicated a significant association between the RNF213 p.Arg4810Lys variant and an increased risk of stenosis progression (P = 0.03, odds ratio 3.2; 95% confidence interval, 1.1–9.0). The RNF213 p.Arg4810Lys variant exhibits clinical disparities in asymptomatic ICAS and is notably linked to a heightened risk of stenosis progression. These results suggest a distinct difference in the vascular stenosis mechanism associated with this variant, warranting further investigation into its clinical implications and potential mechanistic insights.
Seven-Core Fiber Composite Structures-Based Mach-Zehnder Interferometer for Bending and Temperature Measurement
Authors: Zhang Kai , Ling Qiang , Chen Yao , Luo Si , Zhang Yusheng , Zhou Yan , Feng Gaofeng , Yang Junyong , Yu Zhangwei , Chen Haiyun , Jiang Xiuli , Guan Zuguang , Chen Daru 
Published: November 2024

AbstractIn the paper, an optical fiber sensor based on a seven-core fiber composite structure is presented, which enables dual-parameter sensing of bending and temperature. The proposed structure is fabricated by combining the strongly-coupled seven-core fibers (SC-SCFs) and a weakly-coupled seven-core fiber (WC-SCF). The SC-SCF acts as a beam coupler and enhances the Mach-Zehnder interference, while the WC-SCF serves as the enhanced section of another Mach-Zehnder interference. Therefore, the spectrum response of the fiber structure mentioned above exhibits a superposition effect of two Mach-Zehnder interferometers (MZIs). Among them, two dips corresponding to different MZIs are used to measure bending and temperature. The experimental results show the bending sensitivity and temperature sensitivity of the two MZIs are −4.238 nm/m−1, −2.263 nm/m−1, 0.047 nm/°C, and 0.064 nm/°C, respectively. It proves that our sensor is very sensitive to bending. Through the dual-wavelength matrix method, the bending and temperature can be measured simultaneously. With the benefit of the composite structure, low cost, and ease of fabrication, the proposed sensor can be used in harsh environments.
The fertile island effect is stronger for larger plants irrespective of ecosystem productivity
Authors: Fitzpatrick Callum , Stewart Jana , Sutton Andres , Eldridge David J. 
Published: November 2024

Abstract
Productivity and function of arid and semiarid ecosystems (drylands) are optimised when critical resources such as water, organic matter and nutrients are assembled into discrete patches known as fertile patches or fertile islands. The strength of these islands is greater when the focal island plants are larger, but it is unclear whether this size effect holds true within similar-sized island species or across gradients in productivity. We examined the strength of the fertile island effect beneath three shrub species of similar structure but varying size across a gradient in productivity from ranges (low productivity), to footslopes (intermediate) and plains (high productivity). We predicted that fertility effects would be greater for larger plants and under lower productivity. There was no evidence of a productivity effect, but the fertility island effect increased with shrub size, irrespective of species. Furthermore, the fertile island effect was stronger for plant-related attributes (plants and litter) than functions associated with either soil fertility or soil stability. Our results reinforce the notion that plant size is an important determinant of the extent to which perennial plants enhance their understorey environment, irrespective of productivity or species. This has important implications for restoration programmes involving shrub plantings where the aim is to enhance the functionality of degraded dryland systems.
The digestible indispensable amino acid score (DIAAS) in eggs and egg-containing breakfast meals is greater than in toast breads or hash browns served without eggs
Authors: Fanelli Natalia S. , Martins Juliana C. F. R. , Stein Hans H. 
Published: November 2024

Abstract
The objectives of this experiment were to determine the digestible indispensable amino acid score (DIAAS) for eggs cooked in different forms and in traditional egg-bread or egg-hash brown combinations, and to test the hypothesis that DIAAS in eggs is greater than in breads or potatoes. Nine ileal cannulated gilts (average initial body weight: 51.1 ± 6.0 kg) were allotted to a 9 × 6 Youden square design with nine diets and six 7-day periods. Fried egg, boiled egg, scrambled egg, English muffin, Texas toast, and hash brown were included in the experiment. Six diets each contained one source of protein and three diets were combinations of fried eggs and English muffin, boiled eggs and Texas toast, or scrambled egg and hash brown. A nitrogen-free diet was also used and fed to all pigs in one period. The standardised ileal digestibility (SID) of crude protein (CP) and amino acids (AA) was calculated, and DIAAS was calculated for the individual ingredient and combined meals for children between 6 and 36 months and individuals older than 3 years. For both age groups, all cooked eggs had greater (P < 0.001) DIAAS compared with the other foods, and hash brown had greater (P < 0.001) DIAAS than both breads. All combined meals had DIAAS greater than 75 and there were no differences between measured and predicted DIAAS for the combined meals. In conclusion, eggs have ‘excellent’ protein quality for individuals older than 6 months and can compensate for the lower protein quality in plant-based foods, and DIAAS obtained from individual ingredients are additive in mixed meals.
A new biomechanical approach to cranial suture function: the role of contact elements in linear and nonlinear models
Authors: Garcia-Escolà Laia , Fortuny Josep , Marcé-Nogué Jordi 
Published: November 2024

AbstractUnderstanding cranial sutures and how they relieve and dissipate stress is essential to assess their role in cranial biomechanics and to develop highly accurate predictive models. This involves examining how ontogeny affects cranial sutures, as well as their morphology and function, and how these changes through time may impact essential biomechanical loadings such as chewing or direct biting. In this work, we study the cranial sutures of Crocodylus niloticus in detail using contact elements under finite element analysis. Contact elements permit the creation of a physical relationship between two bones that are in contact and even the configuration of these relationships, for example, in terms of movement or flexibility. The definition of bone contacts may require linear and/or nonlinear computational solutions to attain higher accuracy. Herein, skull geometry is tested to determine how bones may be altered by different types of contacts under various conditions. As predicted, the absence of sutures or cranial kinesis leads to a reduction in stress distribution across the skull, whereas sutures and cranial kinesis help the skull relieve stress and prevent certain bones from sustaining high stress levels. The type of contact used in individual sutures has a significant effect on model outcomes. Additionally, feeding behaviors significantly impact cranial biomechanics, reflecting the influence of other variables that may be applied to the models. As highlighted by the results, in order to obtain accurate results when analyzing fossil taxa, the nature of the cranial sutures should be taken into account. Therefore, developing predictive models based on living taxa is invaluable, because it facilitates the study of extinct taxa for which there is a lack of information on the fibrous joints due to poor or no preservation in the fossil record.
Development of the Dutch Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet and its scoring system, alongside the modification of a brief FFQ for assessing dietary adherence
Authors: Beers Sonja , van Houdt Sofie , de Jong Hanne B. T. , de Vries Jeanne H. M. , van de Rest Ondine , de Groot Lisette C. P. G. M. , de van der Schueren Marian A. E. 
Published: November 2024

Abstract
The Mediterranean-Dietary Approach to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) diet is a dietary pattern designed to prevent cognitive decline. Dietary adherence is assessed with the MIND diet scoring system, which is currently based on the American diet and serving sizes. It is known that serving sizes and consumed food products differ between countries. Existing literature lacks reporting on food products included within the MIND diet and weight or volume equivalents corresponding to MIND diet servings, impeding accurate comparisons across studies. This study sought to overcome these limitations by evaluating MIND food products consumed in the Dutch context and developing a scoring system based on consumed quantities in weight or volume amounts rather than in standard serving amounts. The third objective was to modify an existing Dutch brief FFQ (Eetscore-FFQ) to evaluate adherence to the MIND diet. We translated nine of the fifteen MIND food groups directly to grams and volumes using the United States Department of Agriculture measurement conversion table. For the remaining food groups, we employed indirect translation to align them as closely as possible to the original MIND diet. These translated quantities in weight and volumes amounts were subsequently rounded to the nearest Dutch household measures, resulting in the culturally adapted MIND-NL diet scoring. The development of the MIND-NL-Eetscore-FFQ, comprising seventy-two food items (forty-one questions), is described. Our adaption approach is reproducible and can be used to customize the MIND diet scoring system to other cultures.
Joint angle synergy-based humanoid robot motion generation with fascia-inspired nonlinear constraints
Authors: Yu Shiqi , Nakata Yoshihiro , Nakamura Yutaka , Ishiguro Hiroshi 
Published: November 2024

AbstractWhen generating simultaneous joint movements of a humanoid with multiple degrees of freedom to replicate human-like movements, the approach of joint synergy can facilitate the generation of whole-body robotic movement with a reduced number of control inputs. However, the trade-off of minimizing control inputs and keeping characteristics of movements makes it difficult to improve movement performance in a simple control manner. In this paper, we introduce an approach by connecting and constraining these joints. It is inspired by the fascia network of the human body, which constrains the whole-body movements of a human. Compared to when only joint synergy is used, the effectiveness of the proposed method is verified by calculating the errors of joint positions of generated movements and human movements. The paper provides a detailed exploration of the proposed method, presenting simulation-experimental results that affirm its effectiveness in generated movements that closely resemble human movements. Furthermore, we provide one possible method on how these concepts can be implemented in actual robotic hardware, offering a pathway to improve movement control in humanoid robots within their mechanical limitations.
Internet of Things and hybrid models-based interpretation systems for surface roughness estimation
Authors: Umamaheswara Raju R. S. , Kottala Ravi Kumar , Madhava Varma B. , Krishna Palla , Barmavatu Praveen 
Published: November 2024

Abstract
Face milling is performed on aluminum alloy A96061-T6 at diverse cutting parameters proposed by the design of experiments. Surface roughness is predicted by examining the effects of cutting parameters (CP), vibrations (Vib), and sound characteristics (SC). Sound characteristics based on surface roughness estimation determine the rarity of the work. In this study, a unique ANN-TLBO hybrid model (Artificial Neural Networks: Teaching Learning Based Algorithm) is created to predict the surface roughness from CP, Vib, and SC. To ascertain their correctness and efficacy in evaluating surface roughness, the performance of these models is evaluated. First off, the CP hybrid model demonstrated an amazing accuracy of 95.1%, demonstrating its capacity to offer trustworthy forecasts of surface roughness values. The Vib hybrid model, in addition, demonstrated a respectable accuracy of 85.4%. Although it was not as accurate as the CP model, it nevertheless showed promise in forecasting surface roughness. The SC-based hybrid model outperformed the other two models in terms of accuracy with a remarkable accuracy of 96.2%, making it the most trustworthy and efficient technique for assessing surface roughness in this investigation. An analysis of error percentages revealed the exceptional performance of SC-based Model-3, exhibiting an average error percentage of 3.77%. This outperformed Vib Model-2 (14.52%) and CP-based Model-1 (4.75%). The SC model is the best option, and given its outstanding accuracy, it may end up becoming the go-to technique for industrial applications needing accurate surface roughness measurement. The SC model’s exceptional performance highlights the importance of optimization strategies in improving the prediction capacities of ANN-based models, leading to significant advancements in the field of surface roughness assessment and related fields. An IoT platform is developed to link the model’s output with other systems. The system created eliminates the need for manual, physical surface roughness measurement and allows for the display of surface roughness data on the cloud and other platforms.
Factors associated with reported need of weight loss support among adults with overweight or obesity: results from a cross-sectional population study in 2022 in Sweden
Authors: Molarius Anu , Karlsson Jan 
Published: November 2024

Abstract

Objective:
The aim of this study was to investigate factors associated with reported need of weight loss support among adults with overweight or obesity in the general population.

Design:
A cross-sectional population study based on a survey questionnaire sent to a random population sample. Multivariate odds ratios for reported need of weight loss support were calculated for socio-economic, lifestyle and health indicators, in total and by gender and age group.

Setting:
Five counties in Sweden in 2022.

Participants:
The study includes 10 069 persons with overweight or obesity (BMI ≥ 25 kg/m2) aged 30–69 years. BMI was based on self-reported weight and height.

Results:
In total, about 20 % reported needing weight loss support. The factors most strongly associated with reported need of weight loss support were obesity and female gender. Lack of social support, economic difficulties, physical inactivity, poor self-rated health, musculoskeletal pain and depression were also associated with reported need of weight loss support, whereas diabetes and hypertension were not. Some differences in these associations were observed between age groups.

Conclusion:
Reported need of weight loss support is more common among women than among men and associated with obesity, lack of social support, economic difficulties, physical inactivity, poor self-rated health, musculoskeletal pain and depression in both genders. These factors are important for planning preventive and weight-control measures among adults with overweight or obesity.