bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Don’t play if you can’t win’: does economic inequality undermine political equality?
Authors: Schäfer Armin , Schwander Hanna 
Published: September 2019

AbstractIn this paper, we investigate whether income inequality negatively affects voter turnout. Despite some progress, the answer to this question is still debated due to methodological disagreements and differences in the selection of countries and time periods. We contribute to this debate by triangulating data and methods. More specifically, we use three kinds of data to resolve the question: first, we use cross-sectional aggregate data of 21 OECD countries in the time period from 1980 to 2014 to study the relationship between inequality and electoral participation. Second, we zoom in on the German case and examine local data from 402 administrative districts between 1998 and 2017. Focusing on within-country variation eliminates differences that are linked to features of the political system. Finally, we combine survey data with macro-data to investigate the impact of inequality on individual voting. This final step also allows us to test whether the effect of income inequality on voter turnout differs across income groups. Taken together, we offer the most comprehensive analysis of the impact of social inequality on political inequality to date. We corroborate accounts that argue that economic inequality exacerbates participatory inequality.
Discrimination of leafy spurge (Euphorbia esula) and purple loosestrife (Lythrum salicaria) based on field spectral data
Authors: Hooge Hom Kathryn M. , Bajwa Sreekala G. , Lym Rodney G. , Nowatzki John F. 
Published: September 2019

AbstractLeafy spurge (Euphorbia esula L.) and purple loosestrife (Lythrum salicaria L.) are invasive weeds that displace native vegetation. Herbicides are often applied to these weeds during flowering, so it would be ideal to identify them early in the season, possibly by the leaves. This paper evaluates the spectral separability of the inflorescences and leaves of these plants from surrounding vegetation. Leafy spurge, purple loosestrife, and surrounding vegetation were collected from sites in southeastern North Dakota and subjected to spectral analysis. Partial least-squares discriminant analysis (PLS-DA) was used to separate the spectral signatures of these weeds in the visible and near-infrared wavelengths. Using PLS-DA, the weeds were discriminated from their surroundings with R2 values of 0.86 to 0.92. Analysis of the data indicated that the bands contributing the most to each model were in the red and red-edge spectral regions. Identifying these weeds by the leaves allows them to be mapped earlier in the season, providing more time for herbicide application planning. The spectral signatures identified in this proof of concept study are the first step before using ultra–high resolution aerial imagery to classify and identify leafy spurge and purple loosestrife.
Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation
Authors: Kim Jung Ha , Kim Kabsun , Kim Inyoung , Seong Semun , Nam Kwang-Il , Kim Kyung Keun , Kim Nacksung 
Published: September 2019

AbstractThe adaptor protein CrkII is involved in several biological activities, including mitogenesis, phagocytosis, and cytoskeleton reorganization. Previously, we demonstrated that CrkII plays an important role in osteoclast differentiation and function through Rac1 activation both in vitro and in vivo. In this study, we investigated whether CrkII also regulates the differentiation and function of another type of bone cells, osteoblasts. Overexpression of CrkII in primary osteoblasts inhibited bone morphogenetic protein (BMP) 2-induced osteoblast differentiation and function, whereas knockdown of CrkII expression exerted the opposite effect. Importantly, CrkII strongly enhanced c-Jun-N-terminal kinase (JNK) phosphorylation, and the CrkII overexpression-mediated attenuation of osteoblast differentiation and function was recovered by JNK inhibitor treatment. Furthermore, transgenic mice overexpressing CrkII under control of the alpha-1 type I collagen promoter exhibited a reduced bone mass phenotype. Together, these results indicate that CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation. Given that CrkII acts as a negative and positive regulator of osteoblast and osteoclast differentiation, respectively, the regulation of CrkII expression in bone cells may help to develop new strategies to enhance bone formation and inhibit bone resorption.
Heightened orofacial, manual, and gait variability in Parkinson’s disease results from a general rhythmic impairment
Authors: Puyjarinet Frédéric , Bégel Valentin , Gény Christian , Driss Valérie , Cuartero Marie-Charlotte , Kotz Sonja A. , Pinto Serge , Dalla Bella Simone 
Published: September 2019

AbstractIndividuals with Parkinson’s disease (PD) experience rhythm disorders in a number of motor tasks, such as (i) oral diadochokinesis, (ii) finger tapping, and (iii) gait. These common motor deficits may be signs of “general dysrhythmia”, a central disorder spanning across effectors and tasks, and potentially sharing the same neural substrate. However, to date, little is known about the relationship between rhythm impairments across domains and effectors. To test this hypothesis, we assessed whether rhythmic disturbances in three different domains (i.e., orofacial, manual, and gait) can be related in PD. Moreover, we investigated whether rhythmic motor performance across these domains can be predicted by rhythm perception, a measure of central rhythmic processing not confounded with motor output. Twenty-two PD patients (mean age: 69.5 ± 5.44) participated in the study. They underwent neurological and neuropsychological assessments, and they performed three rhythmic motor tasks. For oral diadochokinesia, participants had to repeatedly produce a trisyllable pseudoword. For gait, they walked along a computerized walkway. For the manual task, patients had to repeatedly produce finger taps. The first two rhythmic motor tasks were unpaced, and the manual tapping task was performed both without a pacing stimulus and musically paced. Rhythm perception was also tested. We observed that rhythmic variability of motor performances (inter-syllable, inter-tap, and inter-stride time error) was related between the three functions. Moreover, rhythmic performance was predicted by rhythm perception abilities, as demonstrated with a logistic regression model. Hence, rhythm impairments in different motor domains are found to be related in PD and may be underpinned by a common impaired central rhythm mechanism, revealed by a deficit in rhythm perception. These results may provide a novel perspective on how interpret the effects of rhythm-based interventions in PD, within and across motor domains.
Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation
Authors: Marinović Zoran , Li Qian , Lujić Jelena , Iwasaki Yoshiko , Csenki Zsolt , Urbányi Béla , Yoshizaki Goro , Horváth Ákos 
Published: September 2019

AbstractZebrafish is one of the most commonly used model organisms in biomedical, developmental and genetic research. The production of several thousands of transgenic lines is leading to difficulties in maintaining valuable genetic resources as cryopreservation protocols for eggs and embryos are not yet developed. In this study, we utilized testis cryopreservation (through both slow-rate freezing and vitrification) and spermatogonia transplantation as effective methods for long-term storage and line reconstitution in zebrafish. During freezing, utilization of 1.3 M of dimethyl sulfoxide (Me2SO) displayed the highest spermatogonia viability (~60%), while sugar and protein supplementation had no effects. Needle-immersed vitrification also yielded high spermatogonia viability rates (~50%). Both optimal slow-rate freezing and vitrification protocols proved to be reproducible in six tested zebrafish lines after displaying viability rates of >50% in all lines. Both fresh and cryopreserved spermatogonia retained their ability to colonize the recipient gonads after intraperitoneal transplantation of vasa::egfp and actb:yfp spermatogonia into wild-type AB recipient larvae. Colonization rate was significantly higher in dnd-morpholino sterilized recipients than in non-sterilized recipients. Lastly, wild-type recipients produced donor-derived sperm and donor-derived offspring through natural spawning. The method demonstrated in this study can be used for long-term storage of valuable zebrafish genetic resources and for reconstitution of whole zebrafish lines which will greatly improve the current preservation practices.
Influence of dietary linseed oil as substitution of fish oil on whole fish fatty acid composition, lipid metabolism and oxidative status of juvenile Manchurian trout, Brachymystax lenok
Authors: Yu Jianhua , Li Shuguo , Niu Huaxin , Chang Jie , Hu Zongfu , Han Ying 
Published: September 2019

AbstractIn this study, juvenile Manchurian trout, Brachymystax lenok (initial weight: 6.43 ± 0.02 g, mean ± SE) were received for nine weeks with five types of diets prepared by gradually replacing the proportion of fish oil (FO) with linseed oil (LO) from 0% (LO0) to 25% (LO25), 50% (LO50), 75% (LO75), and 100% (LO100). The eicosapentaenoic (EPA) and docosahexaenoic (DHA) composition decreased with increasing inclusion level of LO (P < 0.05). With increasing LO inclusion level, triglyceride (TAG) content of serum increased significantly, however, there was a decrease in high-density lipoprotein cholesterol (HDL) (P < 0.05). LO substitution of FO up-regulated the gene expression level of lipid metabolism-related genes Fatty Acid Desaturases 6 (FAD6), Acetyl-Coa Carboxylase (ACCα), Sterol Regulatory Element Binding Protein 1 (SREBP-1), and Sterol O- Acyl Transferase 2 (SOAT2), and down-regulated the gene expression level of Peroxisome Proliferator-Activated Receptor a (PPARα) (P < 0.05). The SOD activities of both serum and liver in LO100 were significantly lower than in LO25 (P < 0.05). The CAT activity of the liver in LO100 was significantly lower than in LO0 and LO25 (P < 0.05). This study indicates that the Manchurian trout may have the ability to synthesize LC-PUFAs from ALA, and an appropriate LO in substitution of FO (<75%) could improve both the lipid metabolism and the oxidation resistance.
Comparison of botulinum toxin with surgery for the treatment of acute acquired comitant esotropia and its clinical characteristics
Authors: Lang Li-juan , Zhu Yu , Li Zhi-gang , Zheng Guang-ying , Peng Hai-ying , Rong Jun-bo , Xu Li-min 
Published: September 2019

AbstractWe compared the therapeutic effects between botulinum toxin and surgery for acute acquired comitant esotropia (AACE) and analyze its clinical characteristics. The data of the 29 cases, who received treatment for AACE in the Ophthalmic Center of the First Affiliated Hospital of Zhengzhou University and Henan Provincial Ophthalmology Hospital between January 2016 and January 2017, were collected. The 29 cases with AACE were followed for 6 months or more, and received either botulinum toxin injection (group A with 13 cases) or squint correction (group B with 16 cases). The distant and near deviation angles were compared between the two groups before and after treatment. The success rate (total horizontal deviation of 10 prism diopters or less) and stereopsis were compared between the two groups at post-treatment 6 months. At the same time, the relations between distant and near deviation angles were analyzed among different myopia levels and different AACE types. Results indicated that he success rate was not significantly different at post-treatment 6 months (84.6% vs 81.3%, P = 1.00). The distant and near deviation angles were all significantly different one day and one month after treatment (all P < 0.05); but at post-treatment 6 months, they were not significantly different (all P > 0.05) between the two groups. There were no significant differences in the distant and near stereoacuity between the two groups at post-treatment 6 months (all P > 0.05). Among the 25 cases with myopia, the pre-treatment distant deviation angle was significantly higher than pre-treatment near deviation angle in the cases with myopia level >−2.5 D (P < 0.05), and the pre-treatment distant and near deviation angles were all significantly higher in the cases with type-IIAACE than in the cases with type-IIIAACE (all P < 0.05). This study suggests that Botulinum toxin is as effective as surgery in the treatment of AACE at post-treatment 6 months. For the cases with myopia level >−2.5 D, the pre-treatment distant deviation angle is significantly higher than pre-treatment near deviation angle; and both pre-treatment distant and near deviation angles are greater in the cases with type-IIAACE than in the cases with type-IIIAACE.
Kein alter Wein in neuen Schläuchen!
Authors: Hundenborn Gertrud , von Germeten-Ortmann Brigitte 
Published: September 2019

ZusammenfassungZum 1. Januar 2020 tritt das neue Pflegeberufegesetz in Kraft. Prof.
Gertrud Hundenborn und Brigitte von Germeten-Ortmann geben Ihnen als Expertinnen
aus der Fachkommission zur Entwicklung von Rahmenlehr- und
Rahmenausbildungsplänen einen Einblick, was Sie erwartet.
Excited-state proton transfer relieves antiaromaticity in molecules
Authors: Wu Chia-Hua , Karas Lucas José , Ottosson Henrik , Wu Judy I-Chia 
Published: September 2019

Significance
Excited-state proton transfer (ESPT) is universally recognized as a reaction that relaxes the energy of a photoexcited organic compound. It is commonly found in many light-driven processes. Here we identify decisive principles underlying why and when ESPT happens. Our computational investigation of prototypical ESPT reactions finds that the occurrence of ESPT can be explained by an electron-counting rule—Baird’s rule, which remains largely ignored despite having a near–50-y-old history. We emphasize that this surprising connection not only explains the mechanistic principle of ESPT reactions, but it also predicts whether hydrogen bonding interactions that form within and between organic compounds might strengthen or weaken when irradiated by light. Recognizing this relationship has tremendous interpretive merit for organic photochemistry.
A rhetorical perspective on conspiracies
Authors: Zagarella Roberta Martina , Annoni Marco 
Published: September 2019

AbstractIn this paper, we analyze the persuasive effects of conspiracy theories from a rhetorical and argumentative perspective. In particular, we scrutinize a case-study – the story of the “Stamina cure” in Italy –, interpreting it as a particular instance of conspiracy theory. First, we explain what conspiracy theories are, and why they are relevant within the contemporary health debate. Second, we situate our analysis in relation to other theoretical accounts, explaining why a discursive approach may be required to study conspiracies. Third, we investigate our case-study through the lenses of the three “entechnic” proofs of rhetoric:logos, ethos, andpathos. We conclude that a rhetorical approach can shed significant light on how conspiracies achieve their persuasive effect and it provides a first step toward the elaboration of a more comprehensive model to better address the practical and political implications of conspiracy argumentations.
On philosophical argumentation
Authors: Leal Fernando 
Published: September 2019

AbstractPhilosophical argumentation presents a puzzle for pragma-dialectics: both from the perspective of 2500 years of history and from what we can ourselves witness in the present, philosophers seem to be exclusively intent on strengthening and elaborating their differences of opinion. Nothing like that happens in other academic endeavors. This is an anomaly in pragma-dialectical terms because, if philosophical discussants do not want to resolve their differences of opinion, then they would seem to be unreasonable by definition. In other words, no critical discussion would be possible in philosophy because of the peculiar way philosophers argue. The anomaly can, however, be dispelled by using the elementary distinction between single and multiple differences of opinion. It is argued that, in spite of occasional appearances,allphilosophical differences of opinion aremultiple. From that it is argued that the ‘institutional point’ (van Eemeren, 2010) of philosophy is to create the broadest map of arguable positions. If this is true, then philosophers may after all be pursuing a higher-order kind of consensus, bearing in particular on how many arguments can be marshaled around any given philosophical question.
ALTSched: Improved Scheduling for Time-domain Science with LSST
Authors: Rothchild Daniel , Stubbs Christopher , Yoachim Peter 
Published: September 2019

Abstract
Telescope scheduling is the task of determining the best sequence of observations (pointings and filter choices) for a survey system. Because it is computationally intractable to optimize over all possible multiyear sequences of observations, schedulers use heuristics to pick the best observation at a given time. A greedy scheduler selects the next observation by choosing whichever one maximizes a scalar merit function, which serves as a proxy for the scientific goals of the telescope. This sort of bottom-up approach for scheduling is not guaranteed to produce a schedule for which the sum of merit over all observations is maximized. As an alternative to greedy schedulers, we introduce ALTSched, which takes a top-down approach to scheduling. Instead of considering only the next observation, ALTSched makes global decisions about which area of sky and which filter to observe in, and then refines these decisions into a sequence of observations taken along the meridian to minimize airmass. We implement ALTSched for the Large Synoptic Survey Telescope (LSST) and show that it equals or outperforms the baseline greedy scheduler in essentially all quantitative performance metrics. Due to its simplicity, our implementation is considerably faster than OpSim, the simulated greedy scheduler currently used by the LSST Project: a full 10-yr survey can be simulated in 4 minutes, as opposed to tens of hours for OpSim. LSST’s hardware is fixed, so improving the scheduling algorithm is one of the only remaining ways to optimize LSST’s performance. We see ALTSched as a prototype scheduler that gives a lower bound on the performance achievable by LSST.
Mass variance from archival X-ray properties of Dark Energy Survey Year-1 galaxy clusters
Authors: Farahi A , Chen X , Evrard A E , Hollowood D L , Wilkinson R , Bhargava S , Giles P , Romer A K , Jeltema T , Hilton M , Bermeo A , Mayers J , Vergara Cervantes C , Rozo E , Rykoff E S , Collins C , Costanzi M , Everett S , Liddle A R , Mann R G , Mantz A , Rooney P , Sahlen M , Stott J , Viana P T P , Zhang Y , Annis J , Avila S , Brooks D , Buckley-Geer E , Burke D L , Carnero Rosell A , Carrasco Kind M , Carretero J , Castander F J , da Costa L N , De Vicente J , Desai S , Diehl H T , Dietrich J P , Doel P , Flaugher B , Fosalba P , Frieman J , García-Bellido J , Gaztanaga E , Gerdes D W , Gruen D , Gruendl R A , Gschwend J , Gutierrez G , Honscheid K , James D J , Krause E , Kuehn K , Kuropatkin N , Lima M , Maia M A G , Marshall J L , Melchior P , Menanteau F , Miquel R , Ogando R L C , Plazas A A , Sanchez E , Scarpine V , Schubnell M , Serrano S , Sevilla-Noarbe I , Smith M , Sobreira F , Suchyta E , Swanson M E C , Tarle G , Thomas D , Tucker D L , Vikram V , Walker A R , Weller J ,   (DES Collaboration)
Published: September 2019

ABSTRACT
Using archival X-ray observations and a lognormal population model, we estimate constraints on the intrinsic scatter in halo mass at fixed optical richness for a galaxy cluster sample identified in Dark Energy Survey Year-One (DES-Y1) data with the redMaPPer algorithm. We examine the scaling behaviour of X-ray temperatures, TX, with optical richness, λRM, for clusters in the redshift range 0.2 &lt; z &lt; 0.7. X-ray temperatures are obtained from Chandra and XMM observations for 58 and 110 redMaPPer systems, respectively. Despite non-uniform sky coverage, the TX measurements are $\gt 50{{\ \rm per\ cent}}$ complete for clusters with λRM &gt; 130. Regression analysis on the two samples produces consistent posterior scaling parameters, from which we derive a combined constraint on the residual scatter, $\sigma _{\ln T \, |\, \lambda }= 0.275 \pm 0.019$. Joined with constraints for TX scaling with halo mass from the Weighing the Giants program and richness–temperature covariance estimates from the LoCuSS sample, we derive the richness-conditioned scatter in mass, $\sigma _{\ln M \, |\, \lambda }= 0.30 \pm 0.04\, _{({\rm stat})} \pm 0.09\, _{({\rm sys})}$, at an optical richness of approximately 100. Uncertainties in external parameters, particularly the slope and variance of the TX–mass relation and the covariance of TX and λRM at fixed mass, dominate the systematic error. The $95{{\ \rm per\ cent}}$ confidence region from joint sample analysis is relatively broad, $\sigma _{\ln M \, |\, \lambda }\in [0.14, \, 0.55]$, or a factor 10 in variance.
Open Office Space: The Wave of the Future for Academic Health Centers?
Authors: Barnes Janice , Wineman Jean , Adler Nancy 
Published: September 2019

Facing space constraints similar to those experienced by many urban campuses, the University of California, San Francisco (UCSF) looked to innovative office workplace design to curb growing facilities expenditures. Mission Hall, a new office building primarily for desktop and clinical researchers and staff, was designed as an activity-based workplace (ABW), a type of open-space design. ABW was simultaneously being proposed as the template for future UCSF desktop research workspaces. ABWs can be less costly to construct than other designs, and their mix of shared and open workspaces is intended to improve efficiency and interaction. Evaluations of ABWs in corporate settings have yielded mixed results. Examples of ABW buildings for faculty in academic health centers (AHCs) are rare.
The Mission Hall experience provided a unique opportunity to understand the impact of an ABW design on faculty satisfaction, work effectiveness, well-being, and engagement. In a 2016 survey of faculty, 1 year after occupancy, respondents reported adverse changes in all 4 areas. The most common complaints involved noise exposure and lack of visual and auditory privacy. In response to these issues, faculty reported working at home or elsewhere more frequently, making collaboration more difficult. In 2018, UCSF retrofitted the building to create some private offices and adjusted its overall program to balance private office and open workspaces in future projects.
Lessons drawn from this experience can inform workplace solutions at other AHCs. Most critical are the needs to assess functional requirements of work and align design, change management, and technologies to support those requirements.