bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of Health Motivation and Calorie Ending on Preferences for Indulgent Foods
Authors: Choi Jungsil , Jessica Li Yexin , Samper Adriana 
Published: January 2019

Abstract
Food and beverage manufacturers now regularly display “just below” calorie amounts (e.g., 99, 199, 299) in advertisements, presumably to appeal to health-motivated consumers. “Just below” values are those that fall one or more digits below a round number, most commonly seen as nine-ending numbers. However, although nine-ending prices are known to stimulate purchase intent, it is unclear whether or when nine-ending calorie labeling shapes food preferences. The present research shows that when consumers view indulgent foods with just-below (vs. round-ending) calorie amounts, they exhibit higher consumption intentions, purchase intent, and consumption behavior, yet only if they are high in health motivation. This is due to a tendency for health-motivated consumers to overweigh the leftmost digit in multidigit numbers—a cognitive bias known as the “level effect.” This bias results in the perception that just-below (vs. round) -ending indulgent foods have relatively fewer calories, decreasing anticipated guilt and increasing consumption intentions and behavior. The superiority of just-below calorie presentation under health motivation is attenuated with the addition of reference intake labeling (i.e., % daily calorie intake values), which equalizes the magnitude of nine- and round-ending calorie indulgent foods.
Linguistic analysis of datasets for semantic textual similarity
Authors: Wang Chunlin , Castellón Irene , Comelles Elisabet 
Published: January 2019

Abstract
Semantic Textual Similarity (STS), which measures the equivalence of meanings between two textual segments, is an important and useful task in Natural Language Processing. In this article, we have analyzed the datasets provided by the Semantic Evaluation (SemEval) 2012–2014 campaigns for this task in order to find out appropriate linguistic features for each dataset, taking into account the influence that linguistic features at different levels (e.g. syntactic constituents and lexical semantics) might have on the sentence similarity. Results indicate that a linguistic feature may have a different effect on different corpus due to the great difference in sentence structure and vocabulary between datasets. Thus, we conclude that the selection of linguistic features according to the genre of the text might be a good strategy for obtaining better results in the STS task. This analysis could be a useful reference for measuring system building and linguistic feature tuning.
Can the insider–outsider theory explain unemployment hysteresis in OECD countries?
Authors: Bakas Dimitrios , Makhlouf Yousef 
Published: January 2019

Abstract
Insider–outsider theory is often used as a basis for explaining the hysteretic behaviour of unemployment. Despite this, there is no empirical evidence about the validity of this theory on explaining the persistence of unemployment. This article addresses this gap, using various labour market proxies of insiders’ power for the OECD countries over 1960–2013 and employing panel unit root tests that exploit the information contained in these proxies. The results show that although the unemployment rate exhibits a pronounced hysteretic behaviour in OECD countries, this behaviour is reversed once we account for the insider–outsider proxies. Our findings thus validate the role of the insider–outsider theory as a key source of unemployment hysteresis.
Clinical Characteristics and Radiologic Features of Immunocompromised Patients With Pauci-Bacillary Pulmonary Tuberculosis Receiving Delayed Diagnosis and Treatment
Authors: Park Joung Ha , Choe Jooae , Bae Moonsuk , Choi Sungim , Jung Kyung Hwa , Kim Min Jae , Chong Yong Pil , Lee Sang-Oh , Choi Sang-Ho , Kim Yang Soo , Woo Jun Hee , Jo Kyung-Wook , Shim Tae Sun , Kim Mi Young , Kim Sung-Han 
Published: January 2019

Abstract

Background
Pauci-bacillary pulmonary tuberculosis (TB) can be delayed to diagnose and start anti-TB therapy, especially in immunocompromised patients. We therefore evaluated the clinical and radiologic features of these delayed cases.

Methods
Immunocompromised adult patients with pauci-bacillary pulmonary TB were retrospectively enrolled in a tertiary hospital in an intermediate–TB burden country over a 5-year period. We defined “missed TB” or “not-missed TB” patients as those who started anti-TB therapy after or before positive mycobacterial culture results, respectively.

Results
Of 258 patients, 134 (52%) were classified in the missed TB group, and 124 (48%) in the not-missed TB group. Positive results of molecular tests including MTB polymerase chain reaction and/or Xpert TB/RIF were only obtained in the not-missed TB group (54/106, 54%). The median diagnostic delay in the missed TB group was longer than in the other group (30 vs 6 days; P &lt; .001). In the missed TB group, the most common working diagnoses were pneumonia (46, 34%) and lung metastasis of malignancy (40, 30%). Typical radiologic findings for TB, such as upper lobe predominance and centrilobular nodules with tree-in-bud appearance, were less common in the missed TB group than in the other group. Old age (odds ratio [OR], 1.03), solid organ transplant (OR, 3.46), solid tumor (OR, 3.83), and hematologic malignancy (OR, 4.04) were independently associated with missed TB.

Conclusions
Care is needed to differentiate pauci-bacillary TB, especially in immunocompromised patients with the mentioned risk factors, even without the usual radiologic features of TB. Additional rapid diagnostic tests to rule out pauci-bacillary TB are urgently needed.
Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study
Authors: Wook Kim Ki , Allen Digby W , Briese Thomas , Couper Jennifer J , Barry Simon C , Colman Peter G , Cotterill Andrew M , Davis Elizabeth A , Giles Lynne C , Harrison Leonard C , Harris Mark , Haynes Aveni , Horton Jessica L , Isaacs Sonia R , Jain Komal , Lipkin Walter Ian , Morahan Grant , Morbey Claire , Pang Ignatius C N , Papenfuss Anthony T , Penno Megan A S , Sinnott Richard O , Soldatos Georgia , Thomson Rebecca L , Vuillermin Peter J , Wentworth John M , Wilkins Marc R , Rawlinson William D , Craig Maria E ,   The ENDIA Study Group
Published: January 2019

AbstractBackgroundThe importance of gut bacteria in human physiology, immune regulation, and disease pathogenesis is well established. In contrast, the composition and dynamics of the gut virome are largely unknown; particularly lacking are studies in pregnancy. We used comprehensive virome capture sequencing to characterize the gut virome of pregnant women with and without type 1 diabetes (T1D), longitudinally followed in the Environmental Determinants of Islet Autoimmunity study.MethodsIn total, 61 pregnant women (35 with T1D and 26 without) from Australia were examined. Nucleic acid was extracted from serial fecal specimens obtained at prenatal visits, and viral genomes were sequenced by virome capture enrichment. The frequency, richness, and abundance of viruses were compared between women with and without T1D.ResultsTwo viruses were more prevalent in pregnant women with T1D: picobirnaviruses (odds ratio [OR], 4.2; 95% confidence interval [CI], 1.0–17.1; P = .046) and tobamoviruses (OR, 3.2; 95% CI, 1.1–9.3; P = .037). The abundance of 77 viruses significantly differed between the 2 maternal groups (≥2-fold difference; P &lt; .02), including 8 Enterovirus B types present at a higher abundance in women with T1D.ConclusionsThese findings provide novel insight into the composition of the gut virome during pregnancy and demonstrate a distinct profile of viruses in women with T1D.
Histopathological Features of the Development of Intestine and Mesenteric Lymph Node Injury in a Nonhuman Primate Model of Partial-body Irradiation with Minimal Bone Marrow Sparing
Authors: Parker George A. , Li Na , Takayama Kyle , Booth Catherine , Tudor Gregory L. , Farese Ann M. , MacVittie Thomas J. 
Published: January 2019

Abstract
Male rhesus macaques were subjected to partial-body irradiation at 10, 11, or 12 Gy with 5% bone marrow protection. Animals were euthanized when dictated by prospectively determined clinical parameters or at approximately 180 d following irradiation. Histological sections of jejunum, colon, and mesenteric lymph node were stained with hematoxylin and eosin as well as a battery of histochemical and immunohistochemical stains. The immediate postirradiation histopathological alterations in the jejunum and colon were based primarily on injury to rapidly proliferating crypt epithelial cells, though there was evidence of additional radiation-induced fibrogenic responses. There was substantial resolution of the radiation-related mucosal injury through the observation period, but microscopically visible defects in mucosal structure persisted to the end of the observation period. In the later stages of the observation period, the jejunum and colon had overt fibrosis that was most commonly located in the submucosa and serosa, with less microscopically discernible involvement of the mucosa. Mesenteric lymph nodes had an immediate postirradiation reduction in cellularity due to the known effects of irradiation on lymphoid cell populations. In later stages of the observation period the lymph nodes also developed fibrotic changes, possibly related to transmigration of immunomodulatory cells and/or signaling molecules from the radiation-damaged intestine.
Effects of Diet on Late Radiation Injuries in Rats
Authors: Moulder John E. , Fish Brian L. , Cohen Eric P. , Flowers Jessica B. , Medhora Meetha 
Published: January 2019

Abstract
It has been speculated that the addition of antioxidants to diet could act as either radioprotectors or as mitigators of radiation injury. In preparation for studies of the mitigation efficacy of antioxidants, rats were placed on a modified version of AIN-76A, the diet typically used in such studies. This AIN-76A diet is refined and has no synthetic antioxidants or isoflavones. Compared to the natural-ingredient Teklad 8904 diet used in previous studies, use of the AIN-76A diet from 1–18 wk after irradiation significantly reduced injury in a radiation nephropathy model. A confirmation study included an additional arm in which the AIN-76A diet was started 2 wk prior to irradiation; again, the switch to AIN-76A postirradiation mitigated radiation nephropathy (p < 0.001), but switching to the AIN-76A diet preirradiation had no effect (p > 0.2). The two diets do not differ in salt content, but the AIN-76A diet is somewhat lower in protein (18% vs. 24%). The protein source (primarily soy in Teklad 8904 vs. casein in AIN-76A) might explain the effects. However, replacing the casein in AIN-76A with soy did not change the mitigation efficacy of the diet (p > 0.2 for comparison of the different AIN-76A diets). A similar study in a rat radiation pneumonitis model also suggested mitigation by postirradiation use of AIN-76A, although the effect was not statistically significant (p = 0.07). In conclusion, base diet alone can have biologically significant effects on organ radiosensitivity, but the mechanistic basis for the effect and its dependence of timing relative to irradiation are unclear.
Comparison of Organ and Effective Photon Dose Coefficients for Reference Phantoms in Articulated and Upright Postures in Cranial and Caudal Irradiation Geometries
Authors: Bales Kathryn , Dewji Shaheen 
Published: January 2019

Abstract
Traditionally, dose estimations have been performed predominantly using anthropomorphic phantoms in an upright posture. However, an exclusively upright posture could reduce accuracy when estimating organ absorbed and effective doses for exposures in realistic postures. In this work, effective dose coefficients were computed using International Commission on Radiological Protection Publication 103 recommendations for monoenergetic photon plane sources (0.05–20 MeV) directed upward from below the feet (caudal) and downward from above the head (cranial) for articulated adult male and female stylized phantoms. The Monte Carlo radiation transport code and the Phantom With Moving Arms and Legs were used to calculate organ absorbed dose and effective dose coefficients for upright and two bent (45° and 90°) phantom postures. The resulting coefficients for the bent phantoms were compared to those for the upright phantoms to determine whether the upright phantoms provide a comparable and conservative estimate when conducting dose estimations/reconstructions. For the caudal source, most organs received higher doses when in a bent posture. For the cranial source, the breast, brain, and eyes received lower doses in the bent compared to the upright posture, while all other organs received higher doses. The effective doses for the articulated phantoms were higher than for the upright posture for both irradiation geometries, which could have implications when using the traditional model to estimate or reconstruct radiation doses during actual exposures.
Caught in a Web of Confusion: Assessing the Readability of University Webpages for Victims of Sexual Assault
Authors: Duncan Shannon , Yeatts Paul , Kapusta Ann , Allen Denise , Wilson Jennifer , Tilley Donna Scott 
Published: January 2019

ABSTRACT
Assuring the effectiveness of Web sites in communicating critical information to a college student who has experienced sexual assault is important and complex. Recognizing that the average American reads at the eighth grade level, the National Institutes of Health and the American Medical Association recommend that information be written at a sixth-grade reading level. A sample of 10 U.S. institutions of higher education (IHE) Web sites made up the sample of the current study. The IHEs included were all participants in a project called “Cultivating Safe College Campuses,” funded by the Department of Health and Human Services. This study aimed to gain more insight into the readability of college Web sites about sexual assault resources for the intended consumer—college students. The reading level of IHE Web sites with information about sexual assault should align with the reading level of their intended audience. The average readability of sexual assault Webpages for this study's sample of IHEs was over 13, well above the reading level of the average “first time in college” student. All IHEs should review the readability of their Web sites and revise them to use consistent and defined terms and present the material in a way that is clear and accessible for the student who has experienced trauma.
Potency of descending pain modulatory system is linked with peripheral sensory dysfunction in fibromyalgia
Authors: Brietzke Aline Patrícia , Antunes Luciana Conceição , Carvalho Fabiana , Elkifury Jessica , Gasparin Assunta , Sanches Paulo Roberto Stefani , da Silva Junior Danton Pereira , Dussán-Sarria Jairo Alberto , Souza Andressa , da Silva Torres Iraci Lucena , Fregni Felipe , MD Wolnei Caumo 
Published: January 2019

Abstract
Fibromyalgia (FM) is characterized by chronic widespread pain whose pathophysiological mechanism is related to central and peripheral nervous system dysfunction. Neuropathy of small nerve fibers has been implicated due to related pain descriptors, psychophysical pain, and neurophysiological testing, as well as skin biopsy studies. Nevertheless, this alteration alone has not been previously associated to the dysfunction in the descending pain modulatory system (DPMS) that is observed in FM. We hypothesize that they associated, thus, we conducted a cross-sectional exploratory study.
To explore small fiber dysfunction using quantitative sensory testing (QST) is associated with the DPMS and other surrogates of nociceptive pathways alterations in FM.
We run a cross-sectional study and recruited 41 women with FM, and 28 healthy female volunteers. We used the QST to measure the thermal heat threshold (HTT), heat pain threshold (HPT), heat pain tolerance (HPT), heat pain tolerance (HPTo), and conditional pain modulation task (CPM-task). Algometry was used to determine the pain pressure threshold (PPT). Scales to assess catastrophizing, anxiety, depression, and sleep disturbances were also applied. Serum brain-derived neurotrophic factor (BDNF) was measured as a marker of neuroplasticity. We run multivariate linear regression models by group to study their relationships.
Samples differed in their psychophysical profile, where FM presented lower sensitivity and pain thresholds. In FM but not in the healthy subjects, regression models revealed that serum BDNF was related to HTT and CPM-Task (Hotelling Trace = 1.80, P < .001, power = 0.94, R
2 = 0.64). HTT was directly related to CPM-Task (B = 0.98, P = .004, partial-η
2 = 0.25), and to HPT (B = 1.61, P = .008, partial η
2 = 0.21), but not to PPT. Meanwhile, BDNF relationship to CPM-Task was inverse (B = –0.04, P = .043, partial-η
2 = 0.12), and to HPT was direct (B = –0.08, P = .03, partial-η
2 = 0.14).
These findings high spot that in FM the disinhibition of the DPMS is positively correlated with the dysfunction in peripheral sensory neurons assessed by QST and conversely with serum BDNF.
Slipped capital femoral epiphysis in an adult with congenital hypopituitarism
Authors: Huang Yi-Fan , Wang Li-Shen , Zhang Shi , Gao Yu-Hang , Liu Jian-Guo , Qi Xin 
Published: January 2019

Abstract

Rationale:
Slipped capital femoral epiphysis (SCFE) is a common hip problem in adolescents, usually individuals between 8 and 15 years old. Because of the frequent finding of growth abnormalities in affected children, various endocrine disturbances have been reported as the cause of the disease. However, there are few case reports of older patients in previous literature. To the best of our knowledge, congenital hypopituitarism with normal growth hormone (GH) level has not been reported.

Patient concerns:
We describe a 29-year-old man who had a 3-month history of pain in the left hip with tall stature and unobvious secondary sexual characteristics. Laboratory testing showed low thyroxine, low cortisol, low follicle-stimulating hormone, low luteinizing hormone, low testosterone, but normal GH.

Diagnoses:
Brain magnetic resonance imaging showed pituitary hypoplasia. An anteroposterior pelvis radiograph showed severe varus SCFE in the left hip, it was also confirmed with computed tomography scans.

Interventions:
The patient was treated with levothyroxine, hydrocortisone, and testosterone replacement therapy before surgery. We performed open reduction and anatomical reduction by Dunn's procedure.

Outcome:
We have followed this patient for 6 months, the left hip mobility gradually improved. No slip in the contralateral proximal femoral physis has been observed.

Lessons:
When unobvious secondary sexual characteristics and body abnormalities were found in clinical practice, endocrine condition should be evaluated, since the contralateral side may prone to slip due to the lack of endocrine therapy.
The effects of traditional Chinese exercise on hypertension
Authors: Jin Xiao , Pan BiQi , Wu Huanlin , Xu Danping 
Published: January 2019

Abstract

Background:
Several studies have reported the benefits of traditional Chinese exercises (TCEs) on hypertension; however, a consensus regarding the effectiveness and safety of TCEs for patients with hypertension has not been reached.

Methods and results:
Only randomized controlled trials were included in our study. A total of 16 articles involving 1164 patients with hypertension met the inclusion criteria. The results showed that TCEs can reduce BP, blood lipids (including total cholesterol and triglyceride levels) and endothelin levels and improves quality of life in hypertensive patients, however, the low-quality of the included studies made the results be of questionable significance.

Conclusions:
The results of this review suggest that there is no firm evidence to support the objective effectiveness and safety of TCEs for hypertension because of the poor quality of the studies. Well-designed, randomized placebo-controlled trial with objective outcome measures should be conducted in the future.
Does exposure to asbestos cause prostate cancer? A systematic literature review and meta-analysis: Retraction
Authors: Peng Rui , Fang Fang , Chen Zhijun , Yang Shuai , Dai Changyuan , Wang Chengyong , Guan Han , Li Qingwen 
Published: January 2019

Abstract

Objective
The relationship between asbestos and prostate cancer (PCa) is not well understood due to small number of cases. This study aimed to determine the incidence and mortality of PCa among workers or residents exposed to asbestos based on a systematic review and meta-analysis

Methods
All published studies citing the standardized mortality ratio (SMR) or standardized incidence ratio (SIR) of PCa in workers or residents exposed to asbestos were collected by conducting a search on PubMed, EMBASE, Cochrane Library, and Web of Science before April 2018. Standardized mortality rate for PCa with its 95% confidence interval (CI) was pooled using a fixed-/random-effect model in STATA (Version14.0). This study is registered with PROSPERO, number CRD42018095195.

Results
A total of 17 independent studies were included for the analysis. The overall pooled SMR of PCa was 1.22, with a 95% CI of 1.13 to 1.32, with no heterogeneity across the studies (I2 = 18.8%, P = .234). Subgroup analysis shows that exposure to crocidolite, cement, studies conducted in Europe and Oceania, and long study follow-up (≥25 years) all contribute to significantly higher SMR, and we found no evidence of publication bias (Begg test P value = .592, Egger test P value = .874).

Conclusions
This meta-analysis suggested that exposed to asbestos might be associated with an increased risk of PCa. High-exposure level of asbestos could contribute to significantly higher risk of PCa mortality.
Prognostic significance of elevated preoperative neutrophil-to-lymphocyte ratio for patients with colorectal cancer undergoing curative surgery
Authors: Li Hongcai , Zhao Yan , Zheng Fengying 
Published: January 2019

Abstract

Background:
Preoperative neutrophil-to-lymphocyte ratio (NLR) has been suggested as a useful predictive factor for prognosis in patients with various cancers. However, the prognostic value of NLR in patients with colorectal cancer (CRC) remains controversial. Therefore, the goal of this study was to perform a meta-analysis to evaluate the prognostic value of NLR in patients with CRC undergoing curative surgery.

Methods:
PubMed, EMBASE and Cochrane Library databases were searched to screen the relevant studies. Pooled hazard ratio (HR) with 95% confidence interval (CI) was used to assess the associations of preoperative NLR and overall survival (OS), disease-free survival (DFS), recurrence free survival (RFS) and disease specific survival (DSS) by STATA 13.0 software.

Results:
Sixteen studies involving 5897 patients were included in our meta-analysis. Our pooled results demonstrated that high NLR was associated with poor OS (HR: 1.66, 95%CI: 1.36–2.02, P < .001), DFS (HR = 1.54, 95%CI: 1.18–2.02, P = .002), RFS (HR = 2.31, 95%CI: 1.68–3.17, P < .001) and DSS (HR = 2.27; 95% CI: 1.75–2.96, P < .001). When the patients were stratified according to country, sample size, NLR cut-off, follow up and postoperative chemotherapy, high NLR was still significantly correlated with OS. The limitation was that the majority of enrolled studies were retrospective.

Conclusion:
Preoperative NLR may be an effective predictive biomarker for prognosis in patients with CRC. Detection of NLR may be beneficial to identify the high-risk patients who need other antitumor therapies in addition to surgery.