bluuebunny/crossref_metadata_2025_split huggingface dataset:
¿Quién atenúa y cuándo en español?
Authors: De Cock Barbara , Marsily Aurélie , Pizarro Pedraza Andrea , Rasson Marie 
Published: October 2018

AbstractoEn este análisis, abordamos la atenuación en español desde la variación entre géneros discursivos orales (conversaciones, interacciones en clase, debates parlamentarios y entrevistas sociolingüísticas). Basándonos en el análisis deBriz (2007)de la atenuación en conversaciones informales y entrevistas, en la propuesta deFraser (1990)yBlas Arroyo (2005)en cuanto al impacto del contrato conversacional en el carácter marcado o no de una estrategia, y en la propuesta metodológica presentada enBriz y Albelda (2013), proponemos un análisis de algunos fenómenos de atenuación en español peninsular. Mostramos que, tanto en la atenuación del decir como en la atenuación de lo dicho, los fenómenos se distribuyen de forma variada entre los géneros discursivos incluidos. Queda claro, pues, que cada género tiene un perfil distinto en cuanto al uso de la atenuación, lo que tiene un impacto a la vez en el análisis de la atenuación y en el análisis de géneros discursivos.
‘Lo que se debe hacer es cambiar un poco el estilo de vida’
Authors: Hernández Flores Nieves , Rodríguez Tembrás Vanesa 
Published: October 2018

AbstractoEste trabajo estudia las estrategias de atenuación utilizadas en consejos médicos durante consultas de atención primaria. El objetivo es relacionar el uso de atenuantes con el efecto social producido en la imagen de los interactuantes de acuerdo con los roles desempeñados en la interacción concreta. Para tal fin, se analizan, desde perspectivas pragmalingüísticas y sociopragmáticas, dos fragmentos de consultas médicas en que los consejos del médico se realizan utilizando estrategias de atenuación. Los resultados muestran que en caso de existir riesgo para la imagen del paciente el uso de atenuantes consigue el efecto social de atenuar o mitigar los riesgos para la imagen de ambos (cortesía atenuadora); sin embargo, cuando ese riesgo no se evidencia, los atenuantes contribuyen a alcanzar una función de realce de sus respectivas imágenes (cortesía valorizante).
The underestimated worth of predatory and parasitic mites in India: does it really have to import exotic species for biological control?
Authors: Gupta S. K. , Kumar P. S. 
Published: October 2018

Abstract

Predatory and parasitic mites are likely to assume a greater role in crop protection as world attention is now focused on finding out alternative means of agricultural pest management, and some may be beneficial in the medical and veterinary fields. This review on the status of research on predatory and parasitic mites in India is written in the light of the recent push for introduction of exotic phytoseiid mites into the country. It provides an overview of the predatory mites associated with agri-horticultural crops as well as of some insects of public health importance in India and also of some known from outside the country for appreciating their potential. It has information on predatory mites representing 27 families under three orders, viz. Mesostigmata, Trombidiformes (suborder Prostigmata), Sarcoptiformes (suborder Oribatida, cohort Astigmatina and also cohort excluding Astigmatina). Since phytoseiid mites are the most dominant, highly effective, economically important and widespread predators, the major emphasis has been laid on this family. The promising predators that emerged out of this review are:
Amblyseius channabasavannai
,
A. herbicolus
,
A. largoensis
,
Euseius alstoniae
,
E. finlandicus
,
E. ovalis
,
Neoseiulus fallacis
,
N. longispinosus
,
Scapulaseius suknaensis
,
Transeius tetranychivorus
(Phytoseiidae);
Agistemus fleschneri
,
A. industani
,
Eryngiopus coimbatorensis
(Stigmaeidae);
Anystis baccarum
,
Walzia Indiana
(Anystidae);
Cunaxa setirostris
(Cunaxidae);
Pronematus fleshneri
(Lolinidae); and
Pyemotes tritici
(Pyemotidae), all associated with various agri-horticultural crops;
Microtrombidium saharanpuri
and
Arrenurus
species parasitizing housefly and mosquitoes, respectively. Since many of the predatory mite families appear to be still unexplored, those need immediate attention for exploration, documentation and profitable exploitation. The need to give more emphasis and encouragement to indigenous predatory mites than to exotic species is also discussed.
miR-10b-5p Regulates C2C12 Myoblasts Proliferation and Differentiation
Authors: Ge Guihua , Yang Dongli , Tan Ya , Chen Ying , Jiang Dongmei , Jiang Anan , Li Qiang , Liu Yihui , Zhong Zhijun , Li Xuewei , Zhang Shunhua , Zhu Li 
Published: October 2018

ABSTRACT
The development of skeletal muscle is a complex process including myoblasts proliferation and differentiation. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at post-transcriptional level. Increasing evidences indicate that miRNAs are important regulators in myogenic processes. Here, we reported that the expression of miR-10b-5p steadily decreased during myoblasts proliferation, but significantly increased during myoblasts differentiation. The over-expression of miR-10b-5p promoted myoblasts proliferation and blunted myofiber formation in C2C12 cells, while miR-10b-5p down-regulation showed an opposite result. At the same time, we observed that the down-regulation of nuclear factor of activated T-cells 5 (NFAT5) repressed the differentiation of C2C12 cells, and interestingly, miR-10b-5p could suppress NFAT5 expression. Luciferase activity assays confirmed that miR-10b-5p directly target the 3ʹ-untranslated region (3ʹ-UTR) of NFAT5. Overall, we proposed here a novel insight that miR-10b-5p regulates the proliferation and differentiation of C2C12 myoblasts, and the impact on myogenic differentiation is partly through targeting NFAT5.
Abbreviations: NFAT5: nuclear factor of activated T-cells 5; Cyclin B: cycle protein B; Cyclin D1: cycle protein D1; Cyclin E: cycle protein E; CDK4: cyclin-dependent kinase 4; MyoD: myogenic differentiation antigen; MyoG: myogenin; Myf5: myogenic factor 5; MRF4: myogenic regulatory factor 4; MyHC: myosin heavy chain; AQP5: aquaporin-5; CACNA1C: calcium voltage-gated channel subunit alpha1 C; SRF: serum response factor; Pax7: paired box 7; KLF4: Kruppel-like factor 4; 3'-UTR: 3'-untranslated region; GM: growth medium; DM: differentiation medium
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis
Authors: Kondo Masateru , Imanishi Masaki , Fukushima Keijo , Ikuto Raiki , Murai Yoichi , Horinouchi Yuya , Izawa-Ishizawa Yuki , Goda Mitsuhiro , Zamami Yoshito , Takechi Kenshi , Chuma Masayuki , Ikeda Yasumasa , Fujino Hiromichi , Tsuchiya Koichiro , Ishizawa Keisuke 
Published: October 2018

Abstract

BACKGROUND
Several reports from basic researches and clinical studies have suggested that xanthine oxidase (XO) inhibitors have suppressive effects on cardiovascular diseases. However, the roles of a XO inhibitor, febuxostat (FEB), in the pathogenesis of vascular remodeling and hypertension independent of the serum uric acid level remain unclear.

METHODS
To induce vascular remodeling in mice, angiotensin II (Ang II) was infused for 2 weeks with a subcutaneously implanted osmotic minipump. FEB was administered every day during Ang II infusion. Aortic fibrosis was assessed by elastica van Gieson staining. Mouse macrophage RAW264.7 cells (RAW) and mouse embryonic fibroblasts were used for in vitro studies.

RESULTS
FEB suppressed Ang II-induced blood pressure elevation and aortic fibrosis. Immunostaining showed that Ang II-induced macrophage infiltration in the aorta tended to be suppressed by FEB, and XO was mainly colocalized in macrophages, not in fibroblasts. Transforming growth factor-β1 (TGF-β1) mRNA expression was induced in the aorta in the Ang II alone group, but not in the Ang II + FEB group. Ang II induced α-smooth muscle actin-positive fibroblasts in the aortic wall, but FEB suppressed them. XO expression and activity were induced by Ang II stimulation alone but not by Ang II + FEB in RAW. FEB suppressed Ang II-induced TGF-β1 mRNA expression in RAW.

CONCLUSIONS
Our results suggested that FEB ameliorates Ang II-induced aortic fibrosis via suppressing macrophage-derived TGF-β1 expression.
Associations Between Control Beliefs and Response Time Inconsistency in Older Adults Vary as a Function of Attentional Task Demands
Authors: Cerino Eric S , Stawski Robert S , Geldhof G John , MacDonald Stuart W S 
Published: October 2018

Abstract

Objective
Control beliefs are established correlates of cognitive aging. Despite recent demonstrations that response time inconsistency (RTI) represents a proxy for cognitive processing efficiency, few investigations have explored links between RTI and psychosocial correlates. We examined associations among RTI and control beliefs (perceived competence and locus of control) for two choice-response time (RT) tasks varying in their attentional demands.

Method
Control beliefs and RTI were measured weekly for 5 weeks in a sample of 304 community-dwelling older adults (Mage = 74.11 years, SD = 6.05, range = 64–92, 68.58% female).

Results
Multilevel models revealed that for the attentionally demanding task, reporting higher perceived competence than usual was associated with lower RTI for relatively younger participants and greater RTI for relatively older participants. For the less attentionally demanding task, reporting higher perceived competence than usual was associated with lower RTI for relatively older participants. Links between locus of control and RTI were comparatively scant.

Discussion
Our findings suggest that control beliefs may have adaptive and maladaptive influences on RTI, depending on dimension of control beliefs, individual differences in level of control beliefs and age, as well as attentional task demands. Both for whom and when control beliefs can be leveraged to optimize cognitive aging are discussed.
Is the Quality of Nursing Homes Countercyclical? Evidence From 2001 Through 2015
Authors: Huang Sean Shenghsiu , Bowblis John R 
Published: October 2018

Abstract

Background and Objectives
To examine whether nursing homes (NHs) provide better quality when unemployment rates rise (countercyclical) and explore mechanisms contributing to the relationship between quality and unemployment rates.

Research Design and Methods
The study uses the data on privately owned, freestanding NHs in the continental United States that span a period from 2001 through 2015. The empirical analysis relies on panel fixed-effect regressions with the key independent variable being the county-level unemployment rate. NH quality is measured using deficiencies, outcomes, and care process measures. We also examine nursing staff levels, as well as employee turnover and retention.

Results
NHs have better quality when unemployment rates increase. Higher unemployment rates are associated with fewer deficiencies and lower deficiency scores. This countercyclical relationship is also found among other quality measures. In terms of mechanisms, we find higher nursing staff levels, lower employee turnover, and better workforce retention when unemployment rates rise. Improvement in staffing is likely contributing to better quality during recessions. Interestingly, these effects predominately occur in for-profit NHs for deficiencies and staffing levels.

Discussions and Implications
NH quality is countercyclical. With near record-low unemployment rates in 2018, regulatory agencies should pay close attention to NH quality when and where the local economy registers strong growth. On the other hand, the finding of the unemployment rate–staffing/turnover relationship also suggests that policies increasing staffing and reducing employee turnover may not only improve NH quality but also have the potential to smooth quality fluctuations between business cycles.
Scattering Fans
Authors: Reading Nathan 
Published: October 2018

AbstractScattering diagrams arose in the context of mirror symmetry, Donaldson–Thomas theory, and integrable systems. We show that a consistent scattering diagram with minimal support cuts the ambient space into a complete fan. A special class of scattering diagrams, the cluster scattering diagrams, is closely related to cluster algebras. We show that the cluster scattering fan associated to an exchange matrix $B$ refines the mutation fan for $B$ (a complete fan that encodes the geometry of mutations of $B$). We conjecture that, when $B$ is $n\times n$ for $n&gt;2$, these two fans coincide if and only if $B$ is of finite mutation type.
Blockchain-based platforms for genomic data sharing: a de-centralized approach in response to the governance problems?
Authors: Shabani Mahsa 
Published: October 2018

Abstract
Blockchain-based platforms are emerging to provide solutions for technical and governance challenges associated with genomic data sharing. Providing capabilities for distributed data stewardship and participatory access control along with effective ways for enforcement of the data access agreements and data ownership are among the major promises of these platforms.
Nurse-Led, Shared Medical Appointments for Common Gastrointestinal Conditions—Improving Outcomes Through Collaboration With Primary Care in the Medical Home: A Prospective Observational Study
Authors: Novak Kerri L , Halasz Jennifer , Andrews Christopher , Johnston Colleen , Schoombee Willem , Tanyingoh Divine , Kaplan Gilaad G , van Zanten Sander Veldhuyzen , Swain Mark 
Published: October 2018

Abstract

Background
Gastroesophageal reflux disease (GERD), dyspepsia and irritable bowel syndrome (IBS) are common gastrointestinal disorders accounting for a significant demand for specialty care. The aim of this study was to evaluate safety, access and outcomes of patients assessed by a nurse-led, shared medical appointment.

Methods
This prospective observational study utilized a sample of 770 patients referred to a gastroenterology Central Access and Triage for routine GERD, dyspepsia or IBS from 2011 to 2014. Patient demographics, clinical indication, frequency and outcomes of endoscopy, quality of life, wait times and long-term outcomes (&gt;2 years) were compared between 411 patients assigned to a nurse-led, shared medical appointment and 359 patients assigned to clinic for a gastroenterology physician consultation.

Results
The nurse-led, shared medical appointment pathway compared with usual care pathway had shorter median wait times (12.6 weeks versus 137.1 weeks, P &lt; 0.0001), fewer endoscopic exams (50.9% versus 76.3%, P &lt; 0.0001), less gastroenterology re-referrals (4.6% versus 15.6%, P &lt; 0.0001), and reduced visits to the emergency department (6.1% versus 12.0%, P = 0.004). After two years of follow-up, outcomes were no different between the pathways.

Conclusions
Patients with GERD, IBS or dyspepsia who attend the nurse-led, shared medical appointment have improved access to care and reduced resource utilization without increased risk of significant gastrointestinal outcomes after two years of follow-up.
Disappearing act
Authors: Yahr Jayme 
Published: October 2018

Abstract
The American self-made businessman Daniel J. Terra (1911–1996) collected art as a testament to his patriotism and in an attempt to establish his cultural prowess. Between 1971 and his death in 1996, Terra amassed a collection of 605 paintings, works on paper, and sculpture, made possible by a small network of art dealers who aided Terra in his rapid transformation of the American art market. After a failed attempt to donate his collection to the Art Institute of Chicago, Terra created not one, but two museums in Illinois and one in France over the course of twelve years. Each Terra-backed museum struggled to find visitors, structures of support, and strategic vision while under his control. With the disappearance of each museum, the story of Terra’s art collection became inexorably intertwined with concepts of value, identity, and the physical shift from private hobby to public endeavour.
Theories of truth based on four-valued infectious logics
Authors: Da Ré Bruno , Pailos Federico , Szmuc Damian 
Published: October 2018

AbstractInfectious logics are systems that have a truth-value that is assigned to a compound formula whenever it is assigned to one of its components. This paper studies four-valued infectious logics as the basis of transparent theories of truth. This take is motivated (i) as a way to treat different pathological sentences (like the Liar and the Truth-Teller) differently, namely, by allowing some of them to be truth-value gluts and some others to be truth-value gaps and (ii) as a way to treat the semantic pathology suffered by at least some of these sentences as infectious. This leads us to consider four distinct four-valued logics: one where truth-value gaps are infectious, but gluts are not; one where truth-value gluts are infectious, but gaps are not; and two logics where both gluts and gaps are infectious, in some sense. Additionally, we focus on the proof theory of these systems, by offering a discussion of two related topics. On the one hand, we prove some limitations regarding the possibility of providing standard Gentzen sequent calculi for these systems, by dualizing and extending some recent results for infectious logics. On the other hand, we provide sound and complete four-sided sequent calculi, arguing that the most important technical and philosophical features taken into account to usually prefer standard calculi are, indeed, enjoyed by the four-sided systems.
Evidence of a large-scale positive rotation–metallicity correlation in the Galactic thick disc
Authors: Re Fiorentin Paola , Lattanzi Mario G , Spagna Alessandro 
Published: October 2018

ABSTRACT
This study is based on high quality astrometric and spectroscopic data from the most recent releases by Gaia and APOGEE. We select $58\, 882$ thin and thick disc red giants in the Galactocentric (cylindrical) distance range 5 &lt; R &lt; 13 kpc and within |$z$| &lt; 3 kpc, for which full chemo-kinematical information is available. Radial chemical gradients, $\partial \rm {[M/H]} / \partial \rm {R}$, and rotational velocity–metallicity correlations, $\partial V_\phi / \partial \rm {[M/H]}$, are re-derived firmly uncovering that the thick disc velocity–metallicity correlation maintains its positiveness over the 8 kpc range explored. This observational result is important as it sets experimental constraints on recent theoretical studies on the formation and evolution of the Milky Way disc and on cosmological models of Galaxy formation.
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Treatment of Adults With Metastatic Brain Tumors: Executive Summary
Authors: Olson Jeffrey J , Kalkanis Steven N , Ryken Timothy C 
Published: October 2018

Abstract

BACKGROUND
The Congress of Neurological Surgeons systematic review and evidence-based clinical practice parameter guidelines for the treatment of adults with metastatic brain tumors was first published in 2010. Because of the time elapsed since that publication, an update of this set of guidelines based on literature published since is now indicated.

OBJECTIVE
To establish the best evidence-based management of metastatic brain tumors over all commonly used diagnostic and treatment modalities in regularly encountered clinical situations.

METHODS
Literature searches regarding management of metastatic brain tumors with whole brain radiation therapy, surgery, stereotactic radiosurgery, chemotherapy, prophylactic anticonvulsants, steroids, instances of multiple brain metastases, and emerging and investigational therapies were carried out to answer questions designed by consensus of a multidisciplinary writing group.

RESULTS
Recommendations were created and their strength linked to the quality of the literature data available thus creating an evidence-based guideline. Importantly, shortcomings and biases to the literature data are brought out so as to provide guidance for future investigation and improvements in the management of patients with metastatic brain tumors.

CONCLUSION
This series of guidelines was constructed to assess the most current and clinically relevant evidence for management of metastatic brain tumors. They set a benchmark regarding the current evidence base for this management while also highlighting important key areas for future basic and clinical research, particularly on those topics for which no recommendations could be formulated.
The full guideline can be found at: https://www.cns.org/guidelines-treatment-adults-metastatic-brain-tumors/chapter_1.
Cluster formation in the W 40 and Serpens South complex triggered by the expanding H ii region
Authors: Shimoikura Tomomi , Dobashi Kazuhito , Nakamura Fumitaka , Shimajiri Yoshito , Sugitani Koji 
Published: October 2018

Abstract
We present the results of mapping observations covering a large area of 1 square degree around W 40 and Serpens South carried out in the 12CO (J = 1–0), 13CO (J = 1–0), C18O (J = 1–0), CCS (JN = 87–76), and N2H+ (J = 1–0) emission lines with the 45 m Nobeyama Radio Telescope. W 40 is a blistered H ii region, and Serpens South is an infrared dark cloud accompanied by a young cluster. The relation between these two regions, which are separated by ∼20′ on the sky, has not been recognizable so far. We found the C18O emission is distributed smoothly throughout the W 40 and Serpens South regions, and that the two regions seem to be physically connected. We divided the C18O emission into four groups in terms of the spatial distributions around the H ii region which we call 5, 6, 7, and 8 km s−1 components according to their typical LSR velocity, and propose a three-dimensional model of the W 40 and Serpens South complex. We found two elliptical structures in the position–velocity diagrams, which can be explained as part of two expanding shells. One of the shells is small inner shell just around the H ii region, and the other is a large outer shell corresponding to the boundary of the H ii region. Dense gas associated with the young cluster of Serpens South is likely to be located at the surface of the outer shell, indicating that the natal clump of the young cluster is interacting with the outer shell being compressed by the expansion of the shell. We suggest that the expansion of the shell induced the formation of the young cluster.
How Mass Immigration Affects Countries with Weak Economic Institutions: A Natural Experiment in Jordan
Authors: Nowrasteh Alex , Forrester Andrew C , Blondin Cole 
Published: October 2018

Abstract
To what extent does immigration affect the economic institutions in destination countries? While there is much evidence that economic institutions in developed nations are either unaffected or improved after immigration, there is little evidence of how immigration affects the economic institutions of developing countries that typically have weaker institutions. Using the Synthetic Control Method, this study estimates a significant and long-lasting positive effect on Jordanian economic institutions from the surge of refugees from the First Gulf War. The surge of refugees to Jordan in 1990–1991 was massive, equal to 10 percent of Jordan’s population in 1990. Importantly, these refugees were able to have a large and direct impact on Jordanian economic institutions because they could work, live, and vote immediately upon entry due to a quirk in Jordanian law. The refugee surge was the main mechanism by which Jordan’s economic institutions improved in the decades that followed.