bluuebunny/crossref_metadata_2025_split huggingface dataset:
Child Abuse and Neglect as Risk Factors for Comorbidity Between Depression and Chronic Pain in Adulthood
Authors: Macedo Brisa Burgos Dias , von Werne Baes Cristiane , Menezes Itiana Castro , Juruena Mario F. 
Published: June 2019

Abstract
It is estimated that comorbidity between depression and chronic pain reaches more than half of the depressed adult patients around the world. Evidence indicates that some stressors, such as early-life stress (ELS), mediate the co-occurrence of depression and chronic pain. This study aimed to assess whether ELS or any of its subtypes could be considered as risk factors for comorbidity between depression and chronic pain. For this purpose, 44 patients in depressive episode were evaluated, in which 22 were diagnosed with depression and chronic pain, and the other 22 patients were diagnosed with depression but without chronic pain. Results had shown that ELS occurrence is more significant among depressive patients with chronic pain compared with those without pain. When subtypes of ELS were evaluated, the group of depressive patients with pain showed significantly higher prevalence of emotional neglect than those depressive participants without pain. Data analysis has shown that severity of the depressive symptoms has a significant impact on the total score of childhood trauma, emotional abuse, physical abuse, emotional neglect, and physical neglect, and that emotional abuse, sexual abuse, and physical neglect have significant impact on the severity of depression. In conclusion, our findings indicate that ELS can be considered as a risk factor for the comorbidity between depression and chronic pain.
Psychologic Morbidity Among Psoriatic Arthritis Patients in Remission or With Low Disease Activity
Authors: Wohl Yonit , Reitblat Olga , Lerman Tsahi T. , Cohen Ornit , Reitblat Tatiana 
Published: June 2019

Objective
The aim of this study was to compare the effect of biologic agents and conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) on the psychologic status of patients with psoriatic arthritis (PsA) in remission or with low disease activity.

Methods
This is a case-control study of PsA patients in remission or with low disease activity treated at a single-center combined rheumatologic-dermatologic clinic between 2015 and 2017. Patients were assigned to 2 comparison groups according to their treatment (1) biologic drugs and (2) csDMARDs therapy. Psoriatic arthritis disease activity was evaluated by disease activity score-28. Anxiety, somatization, and depression were evaluated by patient health questionnaires (PHQ): generalized anxiety disorder-7, PHQ-15, and PHQ-9, respectively. Disability was assessed by the health assessment questionnaire disability index (HAQ-DI).

Results
Thirty PsA patients on biologic treatment (BT) and 14 PsA patients in csDMARDs were enrolled. No significant differences in disease duration and treatment duration between the 2 groups were found. Disease activity score-28 was significantly better in the BT group compared with the csDMARDs group (1.8 ± 0.4 vs 2.1 ± 0.4, respectively, p = 0.028). A nonsignificant tendency toward higher scores in psychologic questionnaires was seen among the non-BT group. Moderate to high correlations between all mental questionnaires and HAQ-DI were found in both groups (0.567 ≤ r ≤ 0.850, p < 0.05). Patients with mental disturbance (generalized anxiety disorder-7/PHQ-15/PHQ-9 ≥ 5) showed significant poorer performance in their HAQ-DI in comparison with patient without physiological comorbidities in both groups.

Conclusions
Tight disease control in PsA patients, achieved with BT, may offer an improvement in psychological outcomes in addition to relieving clinical symptoms.
An Evaluation of Emergency Hand Coverage in Tennessee After Implementation of the Affordable Care Act
Authors: Jackson Kianna R. , Nixon Alexander T. , Pollins Alonda , Mueller Melissa A. , Thayer Shelby M. , Anthony Joshua R. , Thayer Wesley P. 
Published: June 2019

Abstract
Although the upper extremity is the most commonly injured part of the body, many studies have indicated that there is a lack of emergency hand coverage in the United States. In 2010, our laboratory evaluated on-call hand coverage in Tennessee (TN) and found that only 7% of hospitals had a hand surgeon on call for emergency cases at all times. In 2014, the Affordable Care Act (ACA) was implemented with the goal of increasing overall access to care and decreasing health care costs. Hand surgeons were surveyed on their attitudes toward the ACA, and the majority of surgeons surveyed disagreed or strongly disagree that the ACA would improve access to emergent hand surgery. This study aimed to determine if there has been an increase in emergency hand coverage in TN since the implementation of the ACA. A survey was administered to all hospitals in TN with both an emergency department and operating room to determine the percentage of TN hospitals offering elective hand surgery and on-call emergency hand coverage. With 94% of TN hospitals responding to the emergency department survey, we determined that there has been a 138% significant increase in the percentage of hospitals reporting 24/7 emergency hand coverage by a hand specialist since our last study in 2010. There has also been a significant increase in elective hand coverage in TN, although much smaller at 13% since 2010. This study suggests that there has been an overall increase in access to hand care in TN since the implementation of the ACA, most profoundly seen in the increase in hand specialists available for emergent cases.
Mechanical properties of plasma membrane vesicles correlate with lipid order and viscosity and depend on cell density
Authors: Steinkühler Jan , Sezgin Erdinc , Urbančič Iztok , Eggeling Christian , Dimova Rumiana 
Published: June 2019

AbstractPlasma membranes dynamically respond to external cues and changing environment. Quantitative measurements of these adaptations can elucidate the mechanism that cells exploit to survive, adapt and function. However, cell-based assays are affected by active processes while measurements on synthetic models suffer from compositional limitations. Here, as a model system we employ giant plasma membrane vesicles (GPMVs), which largely preserve the plasma membrane lipidome and proteome. From analysis of fluorescence emission and lifetime of environment-sensitive dyes, and membrane shape fluctuations, we investigate how plasma membrane order, viscosity and bending rigidity are affected by different stimuli such as cell seeding density in three different cell models. Our studies reveal that bending rigidity of plasma membranes vary with lipid order and microviscosity in a highly correlated fashion. Thus, readouts from polarity- and viscosity-sensitive probes represent a promising indicator of membrane mechanical properties. Quantitative analysis of the data allows for comparison to synthetic lipid membranes as plasma membrane mimetics.
Olsenella lakotia SW165 sp. nov., an acetate producing obligate anaerobe with a GC rich genome
Authors: Wongkuna Supapit , Ghimire Sudeep , Kumar Roshan , Antony Linto , Chankhamhaengdecha Surang , Janvilisri Tavan , Scaria Joy 
Published: June 2019

ABSTRACTA Gram-positive and obligately anaerobic bacterium was isolated from cecal content of feral chickens in Brookings, South Dakota, USA. The microorganism grew at 37-45° C and pH 6-7.5. This strain produced acetic acid as the primary metabolic end product. Major fatty acids were C12:0, C14:0, C14:0 DMA and summed feature 1 (C13:1 at 12-13 and C14:0 aldehyde). Phylogenetic analyses based on 16S rRNA gene sequence suggested that strain SW165 belongs to the family Atopobiaceae with the closest relatives being Olsenella profusa DSM 13989T (96.33% similarity), Olsenella umbonate DSM 26220T (96.18%) and Olsenella uli DSM 7084T (96.03%). Genome sequencing revealed a genome size of 2.43 Mbp with a G+C content of 67.59 mol%, which is the highest G+C content among members of the genus Olsenella. Phylogenetic and phenotypic comparison indicated that strain SW165 represents a novel species of the genus Olsenella, for which the name Olsenella lakotia sp. nov. is proposed. The type strain is SW165 (=DSM 107283T).
Impact of Influent Carbon to Phosphorus Ratio on Performance and Phenotypic Dynamics in Enhanced Biological Phosphorus Removal (EBPR) System - Insights into Carbon Distribution, Intracellular Polymer Stoichiometry and Pathways Shifts
Authors: Majed Nehreen , Gu April Z. 
Published: June 2019

AbstractThis study investigated the impact of influent carbon to phosphorus (P) ratio on the variation in P-removal performance and associated intracellular polymers dynamics in key functionally relevant microbial populations, namely, PAOs and GAOs, at both individual and populations levels, in laboratory scale sequencing batch reactor-EBPR systems. Significant variations and dynamics were evidenced for the formation, utilization and stoichiometry of intracellular polymers, namely polyphosphate, glycogen and Polyhydroxyalkanoates in PAOs and GAOs in the EBPR systems that were operated with influent C/P ranged from 20 to 50, presumably as results of phylogenetic diversity changes and, or metabolic functions shifts in these two populations at different influent C/P ratios. Single cell Raman micro-spectroscopy enabled quantification of differentiated polymer inclusion levels in PAOs and GAOs and, showed that as the influent rbCOD/P ratio increases, the excessive carbon beyond stoichiometric requirement for PAOs would be diverted into GAOs. Our results also evidenced that when condition becomes more P limiting at higher rbCOD/P ratios, both energy and reducing power generation required for acetate uptake and PHB formation might shift from relying on both polyP hydrolysis and glycolysis pathway, to more enhancement and dependence on glycolysis in addition to partial/reverse TCA cycle. These findings provided new insights into the metabolic elasticity of PAOs and GAOs and their population-level parameters for mechanistic EBPR modeling. This study also demonstrated the potential of application of single cell Raman micro-spectroscopy method as a powerful tool for studying phenotypic dynamics in ecological systems such as EBPR.
Buoyancy-induced convection from a pair of heated and cooled horizontal circular cylinders inside an adiabatic tilted cavity filled with alumina/water nanofluids
Authors: Corcione Massimo , Habib Emanuele , Quintino Alessandro , Ricci Elisa , Spena Vincenzo Andrea 
Published: June 2019

Purpose
This paper aims to investigate numerically buoyancy-induced convection from a pair of differentially heated horizontal circular cylinders set side by side in a nanofluid-filled adiabatic square enclosure, inclined with respect to gravity so that the heated cylinder is located below the cooled one, using a two-phase model based on the double-diffusive approach assuming that the Brownian diffusion and thermophoresis are the only slip mechanisms by which the solid phase can develop a significant relative velocity with respect to the liquid phase.

Design/methodology/approach
The system of the governing equations of continuity, momentum and energy for the nanofluid, and continuity for the nanoparticles, is solved by a computational code based on the SIMPLE-C algorithm. Numerical simulations are performed for Al2O3 + H2O nanofluids using the average volume fraction of the suspended solid phase, the tilting angle of the enclosure, the nanoparticle size, the average nanofluid temperature and the inter-cylinder spacing, as independent variables.

Findings
The main results obtained may be summarized as follows: at high temperatures, the nanofluid heat transfer performance relative to that of the pure base liquid increases with increasing the average volume fraction of the suspended solid phase, whereas at low temperatures it has a peak at an optimal particle loading; the relative heat transfer performance of the nanofluid has a peak at an optimal tilting angle of the enclosure; the relative heat transfer performance of the nanofluid increases notably as the average temperature is increased, and just moderately as inter-cylinder spacing is increased and the nanoparticle size is decreased.

Originality/value
The two-phase computational code used in the present study incorporates three empirical correlations for the evaluation of the effective thermal conductivity, the effective dynamic viscosity and the coefficient of thermophoretic diffusion, all based on a high number of literature experimental data.
Development of a 3D CFD aerodynamic optimization tool and application to engine air intake design
Authors: Millot Grégory , Scholz Olivier , Ouhamou Saïd , Becquet Mathieu , Magnabal Sébastien 
Published: June 2019

PurposeThe paper deals with research activities to develop optimization workflows implying computational fluid dynamics (CFD) modelling. The purpose of this paper is to present an industrial and fully-automated optimal design tool, able to handle objectives, constraints, multi-parameters and multi-points optimization on a given CATIA CAD. The work is realized on Rapid And CostEffective Rotorcraft compound rotorcraft in the framework of the Fast RotorCraft Innovative Aircraft Demonstrator Platform (IADP) within the Clean Sky 2 programme.Design/methodology/approachThe proposed solution relies on an automated CAD-CFD workflow called through the optimization process based on surrogate-based optimization (SBO) techniques. The SBO workflow has been specifically developed.FindingsThe methodology is validated on a simple configuration (bended pipe with two parameters). Then, the process is applied on a full compound rotorcraft to minimize the flow distortion at the engine entry. The design of the experiment and the optimization loop act on seven design parameters of the air inlet and for each individual the evaluation is performed on two operation points, namely, cruise flight and hover case. Finally, the best design is analyzed and aerodynamic performances are compared with the initial design.Originality/valueThe adding value of the developed process is to deal with geometric integration conflicts addressed through a specific CAD module and the implementation of a penalty function method to manage the unsuccessful evaluation of any individual.
The impacts of non-uniform magnetic field on free convection heat transfer of a magnetizable micropolar nanofluid
Authors: Namazian Zafar , Mehryan S.A.M. 
Published: June 2019

Purpose
The purpose of this study is to numerically study the heat transfer of free convection of a magnetizable micropolar nanofluid inside a semicircular enclosure.

Design/methodology/approach
The flow domain is under simultaneous influences of two non-uniform magnetic fields generated by current carrying wires. The directions of the currents are the same. Although the geometry is symmetric, it is physically asymmetric. The impacts of key parameters, including Rayleigh number Ra = 103-106, Hartman number Ha = 0-50, vortex viscosity parameter Δ = 0-4, nanoparticles volume fraction φ = 0-0.04 and magnetic number Mnf = 0-1000, on the macro- and micro-scales flows, temperature and heat transfer rate are studied.

Finding
The outcomes show that dispersing of the nanoparticles in the host fluid increases the strength of macro- and micro-scale flows. When Mnf = 0, the increment of the vortex viscosity parameter increases the strength of the particles micro-rotations, while this characteristic is decreased by growing Δ for Mnf ≠ 0. The increment of Δ and Ha decreases the rate of heat transfer. The increment of Ha decreases the enhancement percentage of heat transfer rate because of dispersing nanoparticles, known as En parameter. In addition, the value of Δ has no effect on En. Moreover, the average Nusselt number Nuavg and En remain constant by increasing the magnetic number Mnf for different volume fraction values.

Originality/value
The authors believe that all of the results, both numerical and asymptotic, are original and have not been published elsewhere yet.
Analysis of efficiency of convection in porous geometries (square vs triangular) with multiple discrete heaters on walls
Authors: Das Debayan , Lukose Leo , Basak Tanmay 
Published: June 2019

Purpose
The purpose of the paper is to study natural convection within porous square and triangular geometries (design 1: regular isosceles triangle, design 2: inverted isosceles triangle) subjected to discrete heating with various locations of double heaters along the vertical (square) or inclined (triangular) arms.

Design/methodology/approach
Galerkin finite element method is used to solve the governing equations for a wide range of modified Darcy number, Dam = 10−5–10−2 with various fluid saturated porous media, Prm = 0.015 and 7.2 at a modified Rayleigh number, Ram = 106 involving the strategic placement of double heaters along the vertical or inclined arms (types 1-3). Adaptive mesh refinement is implemented based on the lengths of discrete heaters. Finite element based heat flow visualization via heatlines has been adopted to study heat distribution at various portions.

Findings
The strategic positioning of the double heaters (types 1-3) and the convective heatline vortices depict significant overall temperature elevation at both Dam = 10−4 and 10−2 compared to type 0 (single heater at each vertical or inclined arm). Types 2 and 3 are found to promote higher temperature uniformity and greater overall temperature elevation at Dam = 10−2. Overall, the triangular design 2 geometry is also found to be optimal in achieving greater temperature elevation for the porous media saturated with various fluids (Prm).

Practical implications
Multiple heaters (at each side [left or right] wall) result in enhanced temperature elevation compared to the single heater (at each side [left or right] wall). The results of the current work may be useful for the material processing, thermal storage and solar heating applications.

Originality/value
The heatline approach is used to visualize the heat flow involving double heaters along the side (left or right) arms (square and triangular geometries) during natural convection involving porous media. The heatlines depict the trajectories of heat flow that are essential for thermal management involving larger thermal elevation. The mixing cup or bulk average temperature values are obtained for all types of heating (types 0-3) involving all geometries, and overall temperature elevation is examined based on higher mixing cup temperature values.
Fluid–structure interaction of free convection in a square cavity divided by a flexible membrane and subjected to sinusoidal temperature heating
Authors: Ghalambaz Mohammad , Mehryan S.A.M. , Ismael Muneer A. , Chamkha Ali , Wen D. 
Published: June 2019

Purpose
The purpose of the present paper is to model a cavity, which is equally divided vertically by a thin, flexible membrane. The membranes are inevitable components of many engineering devices such as distillation systems and fuel cells. In the present study, a cavity which is equally divided vertically by a thin, flexible membrane is model using the fluid–structure interaction (FSI) associated with a moving grid approach.

Design/methodology/approach
The cavity is differentially heated by a sinusoidal time-varying temperature on the left vertical wall, while the right vertical wall is cooled isothermally. There is no thermal diffusion from the upper and lower boundaries. The finite-element Galerkin technique with the aid of an arbitrary Lagrangian–Eulerian procedure is followed in the numerical procedure. The governing equations are transformed into non-dimensional forms to generalize the solution.

Findings
The effects of four pertinent parameters are investigated, i.e., Rayleigh number (104 = Ra = 107), elasticity modulus (5 × 1012 = ET = 1016), Prandtl number (0.7 = Pr = 200) and temperature oscillation frequency (2p = f = 240p). The outcomes show that the temperature frequency does not induce a notable effect on the mean values of the Nusselt number and the deformation of the flexible membrane. The convective heat transfer and the stretching of the thin, flexible membrane become higher with a fluid of a higher Prandtl number or with a partition of a lower elasticity modulus.

Originality/value
The authors believe that the modeling of natural convection and heat transfer in a cavity with the deformable membrane and oscillating wall heating is a new subject and the results have not been published elsewhere.
Conflict resolution role of mediation in labor disputes in Turkey
Authors: Sığrı Ünsal , Karabacak Hakan 
Published: June 2019

Purpose
This paper aims to manage better the conflicts in labor disputes by improving the understanding of mediation dynamics from a game-theoretical perspective.

Design/methodology/approach
Signaling game model is adapted to a hypothetical labor dispute based on the legislative regulations on the mandatory mediation system in Turkey.

Findings
The paper determines mediation equilibria in which both players get positive payoffs. Analysis of the mediation equilibria helps to improve the understanding about the litigation and mediation dynamics depending on the variables. The variables are clearly separated from each other due to their reverse effects on strategy choices of the parties. Mediation payoff and litigation cost are characterized by their incentive effects on mediation preferences, whereas mediation fee and litigation payoff are characterized by their disincentive effect. While increasing amounts of incentive variables strengthen the mediation tendency of the employee, increasing amounts of disincentive variables reveal the opposite effect. Furthermore, the analysis also indicates that if the litigation payoff is too small to recover litigation costs, accepting the mediation becomes the optimal strategy. This prediction is contrary to that of traditional game-theoretic litigation/settlement models, in which small-claim disputes typically cannot be settled.

Practical implications
The assumption that the mediation fee is not a part of the litigation cost eliminates the disincentive effect of mediation fee and makes it neutral on the strategy choice of employee.

Originality/value
This paper first analyzes the strategic role of mediation in labor disputes by using a signaling game. Despite its mediation focus, the paper also provides practical insights for litigation.
Effects of parental cultural capital on purchase intention of cognac
Authors: Wei Yujie , Bergiel Blaise , Song Lingfang 
Published: June 2019

Purpose
The purpose of this paper is to examine the possibility that individual differences in consumer choice of cognac are at least partially influenced by parental cultural capital. Also examined are ten value orientations factors (e.g. hedonism and self-direction) and attitudes toward France, cognac’s country-of-origin that may affect the degree of this intergenerational influence.

Design/methodology/approach
The survey research measures parents’ cultural capital, value orientations and attitude toward France and purchase intention using recognized scales. Data were collected from the faculty and students of a major university located in the southeast of the USA. The sample size was 234.

Findings
The results confirm that parental cultural capital, consumer value orientations and attitudes toward France have significant impacts on the consumer’s willingness to purchase cognac. Adult children of high cultural capital parents are more likely to buy cognac.

Practical implications
The findings of this paper provide meaningful insights into intergenerational influences on consumer purchase intention of cognac and socialization theory. The paper provides several managerial implications for segmentation, targeting and positioning of cognac in the US market.

Originality/value
As the first of its kind, this paper introduces the parents’ cultural capital into the consumer research regarding cognac. The longer-term effects that parents can have on grown children’s consumer behavior are confirmed, suggesting that parental influence persists well into adulthood and has impact on their brand preference.