bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-resolution and High-accuracy Topographic and Transcriptional Maps of the Nucleosome Barrier
Authors: Chen Zhijie , Gabizon Ronen , Brown Aidan I. , Lee Antony , Song Aixin , Celis César Díaz , Koslover Elena F. , Yao Tingting , Bustamante Carlos 
Published: May 2019

AbstractNucleosomes represent mechanical and energetic barriers that RNA Polymerase II (Pol II) must overcome during transcription. A high-resolution description of the barrier topography, its modulation by epigenetic modifications, and their effects on Pol II nucleosome crossing dynamics, is still missing. Here, we obtain topographic and transcriptional (Pol II residence time) maps of canonical, H2A.Z, and monoubiquitinated H2B (uH2B) nucleosomes at near base-pair resolution and accuracy. Pol II crossing dynamics are complex, displaying pauses at specific loci, backtracking, and nucleosome hopping between wrapped states. While H2A.Z widens the barrier, uH2B heightens it, and both modifications greatly lengthen Pol II crossing time. Using the dwell times of Pol II at each nucleosomal position we extract the energetics of the barrier. The orthogonal barrier modifications of H2A.Z and uH2B, and their effects on Pol II dynamics rationalize their observed enrichment in +1 nucleosomes and suggest a mechanism for selective control of gene expression.HighlightsA single-molecule unzipping assay mimics DNA unwinding by Pol II and maps the topography of human canonical, H2A.Z and uH2B nucleosome barriers at high resolutionReal-time dynamics and full molecular trajectories of Pol II crossing the nucleosomal barrier reveal the transcriptional landscape of the barrier at high accuracyH2A.Z enhances the width and uH2B the height of the barrierA unified mechanical model links position-dependent dwell times of Pol II on the nucleosome with energetics of the barrier
A multi-level society comprised of one-male and multi-male core units in an African colobine (Colobus angolensis ruwenzorii)
Authors: Stead Samantha M. , Teichroeb Julie A. 
Published: May 2019

AbstractA few mammalian species exhibit complex, nested social organizations, termed multi-level societies. Among nonhuman primates, multi-level societies have been confirmed in several African papionin and Asian colobine species. Using data on individually-recognized Rwenzori Angolan colobus at Lake Nabugabo, Uganda, we document the first multi-level society in an African colobine. The study band comprised up to 135 individuals living in 12 socially and spatially distinct core units that ranged in size from 4 to 23 individuals. These core units shared a home range, and fissioned and fused throughout the day. Using the association indices between core units, we employed hierarchical cluster analyses and permutation tests to show that some core units clustered into clans. Thus, we confirm three tiers of social organization for Rwenzori Angolan colobus: core unit, clan, and band. The social organization of this subspecies is unlike any reported previously in a nonhuman primate, with about half the core units containing a single adult male and the others containing multiple reproductive adult males. Preliminary data show males to transfer within the band and female to transfer outside of the band, which suggests that, like Hamadryas baboons, this subspecies could provide insight into the selective pressures underlying hominin social organization.
Changes in the microbial community of Lubomirskia baicalensis affected by Brown Rot Disease
Authors: Colin ROREX , Sergej BELIKOV , Natalia BELKOVA , Lubov Chernogor , Igor Khanaev , Armen Nalian , Alexandra Martynova-Van Kley 
Published: May 2019

AbstractSponge diseases occur globally and the resulting reduction of sponge populations has negative effects on other organisms within the ecosystems due to loss of nutrient enrichment and loss of bioremediation. In Lake Baikal, the predominate sponge species Lubomirskia baicalensis is currently being infected with an unidentified pathogen resulting in a sharp decline in population. The current hypothesis is that the recent increase in methane concentration in the lake has caused dysbiosis within the bacterial community of L. baicalensis resulting in the disease outbreak. In this study we investigated the changes in the bacterial community between healthy and sick sponges using 16S bacterial profiling targeting veritable regions 3-5. Here we present data that the bacterial communities of the healthy sponge samples were significantly different from sick samples and several poorly classified organisms were identified by Indicator Species Analysis as significant. Organisms identified from the sick samples classified within taxonomic units that contain acidophilic bacteria which suggest pH may play a role. There was also an observed decrease in the number of identified methyltropic bacteria present in the sick sponge samples compared to the healthy.
A helminth chitinase structurally similar to mammalian chitinase displays immunomodulatory properties
Authors: Ebner Friederike , Balster Katja , Janek Katharina , Niewienda Agathe , Malecki Piotr H. , Weiss Manfred S. , Sutherland Tara E. , Heuser Arnd , Kühl Anja A. , Zentek Jürgen , Hofmann Andreas , Hartmann Susanne 
Published: May 2019

AbstractPreviously, we reported significant immunomodulatory effects of the entire excretory-secretory (ES) proteins of the first larval stage (L1) of the gastrointestinal nematodeTrichuris suisin a rodent model of allergic hyperreactivity. In the present study, we aimed to identify the proteins accounting for the modulatory effects of theT. suisL1 ES proteins and thus studied selected components for their immunomodulatory efficacy in an OVA-induced allergic airway disease model. In particular, an enzymatically activeT. suischitinase mediated amelioration of airway hyperreactivity, primarily associated with suppression of eosinophil recruitment into the lung. The three-dimensional structure of theT. suischitinase as determined by high-resolution X-ray crystallography revealed significant similarities to mouse acidic mammalian chitinase (AMCase). In addition, the unique ability ofT. suischitinase to form dimers, as well as acidic surface patches within the dimerization region may contribute to the formation of cross-reactive antibodies to the mouse homologs. This hypothesis is supported by the observation thatT. suischitinase treatment induced cross-reactive antibodies to mouse AMCase and chitinase-like protein BRP-39 in the AHR model. In conclusion, a biologically activeT. suischitinase exhibits immunomodulatory properties despite its structural similarity to the mammalian counterpart.Author summaryExperimental immunotherapy via reintroduction of intestinal worms to treat and prevent autoimmune, chronic inflammatory or allergic diseases is being discussed but the underlying mechanisms are still not fully understood. Here, we investigated the immunomodulatory potential of specific proteins of the whipwormTrichuris suisthat are secreted very early during larval development. Using a murine model of allergic lung disease, we show that in particular oneT. suisprotein, functionally characterized as an active chitinase, is reducing the lung inflammation. TheT. suischitinases three-dimensional protein structure revealed remarkable similarities to the hosts’ chitinase, an enzyme known to play a pivotal role in lung allergy. We also show that treatment with the helminth chitinase induced cross-reactive antibody responses against murine chitinase and chitinase-like proteins, both being inflammatory marker and regulators of type 2 immunity. Thus, our study provides a novel mechanism of immunomodulation by helminth components and may contribute to a better understanding of clinical responses of patients receiving helminthic therapy.
Food insecurity among college students in West Texas
Authors: Abu Brenda , Oldewage-Theron Wilna 
Published: May 2019

Purpose
Food insecurity is an evolving nutrition issue affecting both developed and underdeveloped college campuses. The purpose of this paper is to assess food insecurity and related coping strategies among Texas Tech University students.

Design/methodology/approach
This was a cross-sectional online survey in Lubbock, Texas, among college students (n=173). The outcome measures, socio-demographic factors, household food insecurity access) and dietary diversity were assessed using validated tools. Statistical analyses were performed using SPSS software. Socio-demographic differences in food security status were examined using χ2, and means testing. Risks of student food insecurity were assessed using odds ratios (ORs).

Findings
Respondents were mostly female (70 percent), non-Hispanic white (58 percent) and young adults’ (median age: 22.0 (20.0, 27.0)), with a median monthly income of $1,000 (0.0, 1,500) and spent about a fifth of their income on food. More students were food insecure (59.5 percent) compared to those who experienced food security (40.5 percent) (p<0.001). Some of the severe food insecure students (16.7 percent) reported going to bed without food (6.9 percent) in the prior 30 days. Students with monthly food budgets of ⩽ $200 were 3.2 times more likely to be food insecure (OR=3.231: CI: 1.353–7.714; p=0.010) compared to those with higher food budgets. A students’ choice of priority monthly expenses was significantly associated with food security status; however, further risk assessment of dichotomous “prioritized food” and “prioritized other expenses” was not statistically significant.

Originality/value
Student’s food budget of $200 was the strongest determinant of food insecurity. Individual training on money management and meal planning are recommended. University policies should recognize and develop academic support policies addressing competing expenses with food.
Sustainable marketing strategy in food and drink industry: a comparative analysis of B2B and B2C SMEs operating in Europe
Authors: Rudawska Edyta 
Published: May 2019

PurposeThe paper aims to make a contribution by providing a comprehensive understanding of the scope of the implementation of sustainable marketing tools in SMEs operating in the food and drink industry in Europe. The focus will be put on the identification of differences between companies operating in business-to-business (B2B) and business-to-customer (B2C) context.Design/methodology/approachThe empirical basis is a survey of 770 European SMEs, of which 369 operate in Western European countries (including UK, Germany and Spain) and 401 in Central and Eastern Europe (including Poland, Croatia and Russia). The respondents in the particular countries were stratified according to company size, measured by the number of employees. The research covered 316 micro companies, 5 small companies and 209 medium ones. The questionnaire was completed by the managing directors of the enterprises (CEOs) or heads of the marketing departments (CMOs). The research was conducted between April 2016 and January 2017. An in-depth analysis of the findings helped to identify differences between the two groups of SMEs, i.e. operating in the B2B and B2C context, in terms of the extent of sustainable marketing implementation. The non-parametric U Mann–Whitney test was used to examine the significance of the differences between the two groups of companies.FindingsThe research results suggest that both groups of B2B and B2C companies implement sustainable marketing tools to some extent. However, in most cases, B2B organizations do it to a significantly greater extent. Nevertheless, these activities relate mainly to those tools, which are directly visible to customers, both institutional and individual, such as packaging, product ingredients or certificates. To a lesser extent, they involve marketing activities of an internal nature, such as production process and the level of energy, water or resources used.Originality/valueTo the best knowledge of the author, this is the first empirical research study on the implementation of the sustainable marketing concept in SMEs operating in European countries. The study is a comparative analysis of the phenomenon between B2B and B2C companies, which has not been previously researched.
Power advantage: antecedents and consequences in supplier–retailer relationships
Authors: Low Wen Shinn , Li Cheng Ta 
Published: May 2019

PurposeThe research indicates that relatively powerful firms exploit their advantages to damage their weaker partners. However, how power can be abused by advantaged firms remains unclear. This study aims to examine the relationship between power advantage and abuse of power and whether the power advantage mediates the relationship between dependence and personal interests and between trust and company performance.Design/methodology/approachA total of 130 retailers in Taiwan were investigated. Partial least squares regression was performed to test the proposed hypotheses.FindingsThe results of this study show that power-advantaged firms are more likely to abuse their power; however, the purposes are more for their company performance than for personal interests. Power advantage has different mediating effects on the dependence–personal interests and trust–company performance relationships.Research limitations/implicationsConsidering both time and cost limitations, this study investigated one aspect of the retailer–supplier dyad in northern Taiwan. The samples collected may be influenced by the nature of the industry and sampling method, possibly limiting the generalizability of the research results.Practical implicationsThis study can help channel managers with a power advantage to have an improved understanding of their salespersons’ behavioral patterns, particularly gaining personal interests from customers.Originality/valueThis study expands the understanding of the antecedents and consequences of power advantages in supplier–retailer relationships. It also highlights in specific institutional arrangements, the weaker parties’ efforts to endure their counterparts’ use of their power advantage to serve their personal interests. Future research may analyze abuse of power by expanding research to other industries and different cultural contexts.
Green consumption behaviours of consumers within the scope of TPB
Authors: Emekci Simge 
Published: May 2019

Purpose
The purpose of this study is to explain the factors that affect the green buying behaviours and the relations between these factors. For this purpose, three main factors were added to the Ajzen’s theory of planned behaviour (TPB) to develop a more comprehensive model, namely, environmental concern, environmental knowledge and perceived consumer effectiveness (PCE). It is believed that these variables could help understanding the green buying behaviour and extending the TPB model.

Design/methodology/approach
In this study, quantitative research has been made to test the relations in the proposed model. The target population in this research is individuals living in Turkey, both sexes of age over 18 years. The data were collected through an online survey between May and August of 2017. The data were statistically analysed with structural equation modelling and interpreted using the statistical software AMOS version 20.0.

Findings
The findings show that PCE is the variable that has the highest influence on the attitudes towards behaviour, intentions and green buying behaviour in the proposed model. It is possible to say that the PCE variable added to the model is an important variable that improved and strengthened the measurement model. Variables added to the model are compatible with Ajzen’s original model.

Research limitations/implications
The obtained data may not be generalised throughout Turkey. However, it is believed that the data obtained can give a general idea for green buying behaviour of individuals in Turkey.

Practical implications
The obtained data provide a contribution to the marketing communication experts and the literature. Research findings contribute to explaining green consumption behaviours in developing countries.

Originality/value
In this research, the gap between consumers’ attitudes and their behaviours has been researched. Understanding the reason for this gap is essential to increase green consumption in developing countries. The number of studies in this field in Turkey is not very much. For this reason, this study is thought to contribute to the field.
The effect of SOX on audit quality
Authors: Kim Moo Sung , Dandu Jagadish , Iren Perihan 
Published: May 2019

Purpose
This paper aims to investigate two issues. First, the authors test the effect of the Sarbanes–Oxley Act (SOX) on audit quality after 10 years. Second, the authors test whether it was necessary to close all of the Arthur Andersen offices due to the misbehavior of a few (e.g. the Houston and Atlanta offices).

Design/methodology/approach
The authors have used conservatism (Basu) as a proxy for audit quality.

Findings
The authors find that, over the long run (10 years) after SOX adoption, there is a significant positive change in conservatism as compared to during the previous similar period. In addition, the authors find that only 6 of the 20 city-level offices of Arthur Andersen were less conservative than were their other Big 6 competitors in the same city. Furthermore, the results also suggest that some city-level offices of Arthur Andersen were engaged in more conservative accounting practices than were their competitors and the Houston Andersen offices.

Originality/value
This study documents, using empirical evidence, that the implementation of SOX is successful, and that one factor that helped lead to this success might be the harsh punishment on Arthur Andersen.
The relationship between foreign aid and corruption: a case of selected Asian countries
Authors: Ali Muhammad , Khan Lubna , Sohail Amna , Puah Chin Hong 
Published: May 2019

Purpose
The purpose of this study is to examine the effect of foreign aid (FA) on corruption in selected Asian countries (Pakistan, India, Srilanka and Bangladesh) using the panel data from 2000 to 2014.

Design/methodology/approach
The author used Levin-Lin-Chu and Im-Pesaran-Shin panel unit root tests to check the stationary properties of the variables. The Pedroni’s and Kao panel cointegration approach was applied to analyze the variable’s long-run relationship. The author used panel dynamic ordinary least squares (PDOLS) and fully modified ordinary least squares (FMOLS) framework to estimate the coefficients of cointegrating vectors. Additionally, the panel granger causality test was performed to check the causal relationship between the variables.

Findings
The results from PDOLS and FMOLS indicate that FA has a significant negative impact on the level of corruption. This infers that the foreign assistance decrease the level of corruption perception index, hence, more corruption in the country.

Originality/value
Overall, the study fulfills the need to understand the aid-corruption nexus, particularly in the case of the Asian region.
Conceptualizing corruption prevention: a systematic literature review
Authors: Bautista-Beauchesne Nicholas , Garzon César 
Published: May 2019

PurposeExisting reviews about corruption and anti-corruption have yet to treat the subject of prevention as the main focus of inquiry. The purpose of this paper is to address this need by analyzing definitions, theoretical underpinnings, methods and sectors of interest within published academic articles. By doing so, the main objective is to clarify the theoretical and conceptual foundations of the prevention of corruption.Design/methodology/approachThe research design consists of a systematic literature review, which uses a keyword-string search method across relevant databases. A qualitative and quantitative coding scheme was implemented to provide descriptive statistics.FindingsResults show a need for methodological diversity, theoretical debate and a clarification of the definitional foundations of corruption prevention. Specifically, the results underline a need for more interdisciplinary collaboration between the various fields that study the issue. To this end, a conceptualization of corruption prevention is proposed, built around a two by two matrix, to synthesize existing definitions and spark scholarly debate.Practical implicationsThis paper contributes to the field of anti-corruption on a theoretical level by highlighting the current strengths and weaknesses of the inroads made by the existing literature. Moreover, on a practical research level, this paper suggests fruitful lines of inquiry to channel a rapidly expanding field of study.Social implicationsThis paper underlines the need for corruption prevention policymaking to take note of the broad literature emanating from multiple social science disciplines. This paper also underlines the need for policy implementation to consider the socio-historical context and definitional idiosyncrasies of corruption for policy effectiveness.Originality/valueA core original contribution of this paper is to advance a definition and conceptualization of corruption prevention. Using two conceptual axes – focus and scope – prevention tools are categorized and analyzed to spark further scholarly debate.
Impact of economic and financial crimes on economic growth in emerging and developing countries
Authors: Saddiq Sani Abubakar , Abu Bakar Abu Sufian 
Published: May 2019

Purpose
The purpose of the study is to investigate the impact of economic and financial crimes on the economies of emerging and developing countries.

Design/methodology/approach
Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) guidelines and meta-analysis of economics research reporting guidelines were used to conduct a quantitative synthesis of empirical evidence on the impact of economic and financial crimes in developing and emerging countries.

Findings
A total of 103 studies were searched, out of which 6 met the selection/eligibility criteria of this systematic review. The six selected studies indicated that economic and financial crimes have a negative impact in emerging and developing countries.

Originality/value
To the best knowledge of the authors, no published systematic review of the impact of economic and financial crimes in developing countries has been conducted to date.