bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assujettis, insoumis et contrôle de la pensée : la « guerre future » et ses conséquences dans Le Piège diabolique (1962), bande dessinée d’Edgar P. Jacobs
Authors: Peirano Pierre-François 
Published: February 2019

Dans l’épisode central du Piège diabolique (1962), le dessinateur belge Edgar P. Jacobs dépeint le monde tel qu’il l’imagine en l’an 5060, alors que l’un de ses héros, le professeur Mortimer, voyage dans le temps avec une machine inventée, puis déréglée par l’un de ses rivaux, avide de vengeance. La planète, après avoir été ravagée par une guerre nucléaire, à la fin du XXIe siècle, est alors sous la férule d’un gouvernement totalitaire et cet épisode montre ainsi les conséquences d’une « guerre future », synonyme de régression pour l’humanité entière. Outre l’indéniable influence de romans d’anticipation, principalement ceux de H. G. Wells, la confiscation du progrès technique par une poignée d’hommes et le spectre d’une guerre nucléaire en constituent les principaux traits. Cependant, Jacobs tire également profit de la peinture de cet univers cauchemardesque pour transmettre un message d’espoir et d’humanisme, comme le montre la victoire finale des populations « assujetties », à laquelle Mortimer contribue grandement.
Marcel Pagnol et l’écriture d’une Provence cosmopolite
Authors: Brun Marion 
Published: February 2019

Marcel Pagnol semble un auteur paradoxal pour interroger le rapport de la littérature au cosmopolitisme, lui qui, au contraire, peut incarner la manifestation du repli sur le national et, plus étroitement encore, sur le régional. En vérité, la représentation locale de la Provence engage la définition de l’espace méditerranéen qui est, par excellence, un carrefour d’échanges. Aussi Pagnol décrit-il le monde méridional de façon double : il reprend l’imaginaire latin et hellénique dans une perspective néoclassique, sans nier les influences arabo-sémites. En équilibrant cosmopolitisme et attachement au pays natal, l’écrivain peut être qualifié de nationaliste ouvert.
Automatic high-frequency measurements of full soil greenhouse gas fluxes in a tropical forest
Authors: Courtois Elodie Alice , Stahl Clément , Burban Benoit , Van den Berge Joke , Berveiller Daniel , Bréchet Laëtitia , Soong Jennifer Larned , Arriga Nicola , Peñuelas Josep , Janssens Ivan August 
Published: February 2019

Abstract. Measuring in situ soil fluxes of carbon dioxide (CO2), methane
(CH4), and nitrous oxide (N2O) continuously at high
frequency requires appropriate technology. We tested the combination of a
commercial automated soil CO2 flux chamber system (LI-8100A) with a
CH4 and N2O analyzer (Picarro G2308) in a tropical
rainforest for 4 months. A chamber closure time of 2 min was sufficient for
a reliable estimation of CO2 and CH4 fluxes (100 %
and 98.5 % of fluxes were above minimum detectable flux – MDF,
respectively). This closure time was generally not suitable for a reliable
estimation of the low N2O fluxes in this ecosystem but was
sufficient for detecting rare major peak events. A closure time of 25 min
was more appropriate for reliable estimation of most N2O fluxes
(85.6 % of measured fluxes are above MDF ± 0.002 nmol m−2 s−1). Our study highlights the importance of
adjusted closure time for each gas.
Monitoring the crisis of a rock glacier with repeated UAV surveys
Authors: Vivero Sebastián , Lambiel Christophe 
Published: February 2019

Abstract. In this study, rapid topographic changes and high creeping rates caused by
the destabilisation of an active rock glacier in a steep mountain flank were
investigated in detail with five unmanned aerial vehicle (UAV) surveys
between June 2016 and September 2017. State-of-the-art photogrammetric
techniques were employed to derived high-density point clouds and
high-resolution orthophoto mosaics from the studied landform. The accuracy of
the co-registration of subsequent point clouds was carefully examined and
adjusted based on comparing stable areas outside the rock glacier, which
minimised 3-D alignment errors to a mean of 0.12 m. Elevation and volumetric
changes in the destabilised rock glacier were quantified over the study
period. Surface kinematics were estimated with a combination of image
correlation algorithms and visual inspection of the orthophoto mosaics.
Between June 2016 and September 2017, the destabilised part of the rock
glacier advanced up to 60–75 m and mobilised a volume of around
27 000 m3 of material which was dumped over the lower talus slope. This
study has demonstrated a robust and customisable monitoring approach that
allows a detailed study of rock glacier geometric changes during a crisis phase.
Técnicas de análise de multicritério aplicadas à modelagem do escoamento superficial na bacia do Rio Mundaú, Ceará, Brasil
Authors: César Praciano Sampaio Augusto , De Holanda Bastos Frederico , Monteiro Nunes Cordeiro Abner 
Published: February 2019

A seleção e a priorização de áreas que satisfazem um objetivo específico contribuem para otimizar a tomada de decisões estratégicas no planejamento ambiental, a exemplo da identificação de áreas preferenciais para o controle e a redução das taxas de escoamento, apontada como medida eficaz na preservação das bacias hidrográficas. Dessa forma, objetivou-se elaborar um modelo determinístico do potencial de geração de escoamento superficial na bacia do rio Mundaú, Ceará, Brasil. Foram aplicadas técnicas de Análise de Multicritério, dentre as quais: o método do Processo Hierárquico Analítico e da Média Ponderada Ordenada associada à lógica fuzzy. As variáveis uso e cobertura do solo, declividade, grupo hidrológico do solo,precipitação e fluxo acumulado foram selecionadas como critérios de análise, com base no Coeficiente de Escoamento Superficial e no modelo do Soil Conservation System. Os resultados demonstraram bastante flexibilidade do modelo no espaço estratégico de decisão, permitindo identificar as áreas adequadas à geração de fluxos superficiais. Essas áreas estão localizadas na porção oeste da bacia sobre as suas vertentes mais íngremes.
Palavras-chave: Bacia hidrográfica semiárida, Coeficiente de escoamento superficial, Lógica fuzzy
Associação entre consumo de álcool no padrão binge e tabaco em estudantes de enfermagem
Authors: De Oliveira Prado Sousa Barbara , Thomaz de Souza André Luiz , Cubas Junior Dival , Fulan e Silva Gabriela , Antônio dos Santos Manoel , Cristina Pillon Sandra 
Published: February 2019

O estudo teve por objetivo avaliar o uso de álcool no padrão bingee a sua associação com o tabaco em estudantes de enfermagem. Estudo transversal desenvolvido com 182 estudantes. Foi utilizado formulário informações sociodemográficas, (AUDIT C) e (FTND). Dos participantes, 48,9% foram classificados no padrão binge drinking e 6% eram fumantes. Constatou-se que o binge esteve associado à frequência de uso de álcool, a dose de consumo e a frequência de uso de cinco ou mais doses em uma única ocasião. Além disso, esse padrão de consumo associou-se ao tempo de fumar após acordar, número de cigarros diários, consumo matutino, fumar em qualquer hora do dia, situações de proibição e casos de doença. A prática de binge esteve associada à frequência e à dose de consumo de álcool, assim como ao tabaco, porém, essa conclusão pode não retratar a realidade brasileira por se tratar de uma população específica.
Erfrechtelijke plaatsvervulling en aanwas in het versterferfrecht? Verticale en horizontale doorschuiving!
Authors: Brinkman R.E. 
Published: February 2019

Erfrechtelijke plaatsvervulling en aanwas in het versterferfrecht? Verticale en horizontale doorschuiving!
De auteur betoogt dat in het versterferfrecht de formulering van de plaatsvervulling allerlei vragen oproept; datzelfde geldt bij de ‘aanwas’ ten behoeve van andere erfgenamen bij versterf (als een erfgenaam bijvoorbeeld onwaardig is of zijn erfrecht vervallen wordt verklaard). De auteur poogt aan de hand van de termen verticale en horizontale doorschuiving de werking van de wettelijke regelingen te verduidelijken en geeft een proeve van een nieuwe wettekst.
Refleksiv praksislæring i virtuelle, transparente læringsmiljøer
Authors: Olesen Monica Irene Krarup 
Published: February 2019

Et undervisningsforløb tilrettelagt som blended learning (BL) inddrog ePortfolier som virtuelt værktøj og omdrejningspunkt for social læring og refleksion. Forløbet dannede afsæt for et forskningsprojekt, der ønskede at identificere de læringsfremmende faktorer, som de oplevedes af de pædagogisk diplomstuderende, og at undersøge, om den læring der fandt sted, kunne defineres som refleksiv praksislæring (RPL). I artiklen argumenteres for, at ePortfolie-metodikken skaber mulighed for transparente læringsmiljøer, og at asynkron og skriftlig kommunikation gennem bundne og praksisrettede refleksionsopgaver fremmer udvikling af professionel identitet og professionskompetencer og lægger således op til RPL og udvikling af selvfaciliteringskompetencer.
Keywords: Virtuelle læringsfællesskaber, refleksiv praksislæring, ePortfolier.
Literacia em saúde mental acerca da depressão e abuso de álcool de adolescentes e jovens Portugueses
Authors: Loureiro Luís Manuel 
Published: February 2019

Este estudo tem objectivos comparar a literacia em saúde mental dos adolescentes e jovens portugueses relativamente à depressão e ao abuso de álcool e analisar o padrão de respostas em termos de consistência e concordância para ambas as perturbações.A amostra é constituída por 4938 adolescentes e jovens, 43,0% do género masculino e 56,7% do género feminino, com uma média de idades de 16,75 anos, que frequentam as escolas do 3.º ciclo do ensino básico e do ensino secundário, pertencentes à Direção Regional de Educação do Centro.Os resultados revelam um nível de LSM modesto na generalidade das componentes. Ainda que se encontrem diferenças estatisticamente significativas (p<0,05) em 88,00% dos itens da LSM, o que indicia diferentes formas de encarar ambos os problemas de saúde mental, os resultados revelam consistência em termos das componentes conhecimentos e competências para prestar a primeira ajuda e apoio aos outros e conhecimentos acerca do modo de prevenção das perturbações mentais.
Editorial: A validade nos instrumentos de avaliação
Authors: Espirito Santo Helena 
Published: February 2019

Face ao número crescente de artigos sobre a validação e usos de instrumentos de avaliação que chegam à RPICS, talvez seja o momento para refletir sobre a questão da validade dos mesmos. A RPICS espera que os autores nos seus artigos discutam explicitamente sobre a validade dos instrumentos na secção dos Métodos. Caso os autores utilizem um instrumento estudado previamente com o mesmo formato, com as mesmas características de sujeitos e para o mesmo objetivo, então é suficiente citar a referência prévia. Caso o instrumento seja modificado, o número de itens alterado, o objetivo diferente ou o ponto de corte se modifique, então é necessário apresentar informação suplementar sobre a adaptação. No caso de novos instrumentos criados pelos autores, é essencial explicitar o decurso da elaboração, as medidas de confiabilidade, os resultados do estudo piloto e outras informações que credibilizem o uso do instrumento de avaliação. Seguem-se alguns conceitos fundamentais no domínio da validade e confiabilidade.
Reflections on Efforts Geared toward Improved Soil Fertility and Crop Yields in Kenya
Authors: Chebet Arusey , Njoroge Ruth , Ng’etich Wilson 
Published: February 2019

A successful strategy aimed at enhancing crop productivity relies on its ability to be implemented practically in the field (farmers’ field). Many research-based activities and promising soil fertility technologies are largely not adopted. This paper examines the impact of the agricultural research conducted at the University of Eldoret, agricultural institutes and the government of Kenya projects at a farm level on crop yields. Precisely, this paper narrows down to research done with an aim of exploring system approaches that address soil phosphorus and its effect on increasing crop yields in Western Kenya. Strategies like the collaboration of scientists and non scientists (transdisciplinary process) produced successful results. A qualified soil test with differentiated soil testing recommendations increases the yield by about 1.5 t dry maize ha-1. Participating in a transdisciplinary process provides an additional surplus of about 1 t dry maize ha-1 yield. Economically, this is a highly attractive result; given that soil testing costs around 20 USD, a surplus of 1 t dry maize returns approximately 330 USD. Although literature registers success stories of many research work, there is slow and limited adoption rate of the output by farmers. We suggest the development and expansion of transdisciplinary research and creation of Farmer Research Network to seek a one-size-fits-all solution for farmers to adopt technologies with proven success.
Physical and Conservational Diagnoses of the Hydrographic Micro-Bacy of Rio Farinha
Authors: Magalhães Cavalcante Albergma Estevão De Queiroz , De Mendonça Izaque Francisco Candeia , De Lima Joedla Rodrigues , Medeiros Felipe Silva de , Sousa Silva Roberta Patrícia de , Pereira Justino Sérvio Túlio , Freitas Amanda De Lira , De Almeida Ediglécia Pereira , Vidalett Sávio Ferreira 
Published: February 2019

Introduction: The process of degradation of the environmental system of the Farinha river basin is due to soil inadequacy and natural factors.
Aims: The present work had as objective to evaluate the degree of deterioration of the environmental system of the hydrographic basin of the river Farinha the geo - referenced information are related to the physical characterization of the micro-basin based on the physical conservationist diagnosis of the Geographic Information Systems - GIS.
Methodology: The hydrographic basin of the Farinha River, located in the Center-West region of Paraíba, includes an area of 8.0915,8 ha. Images of the Landsat 8 satellite, OLI sensor in bands 3, 4 and 5 were applied, are classified as a visual and supervised process. With this, the software QGIS 2.18.17 generated vector data and the IDRISI Selva V.17, was used as a means to process the raster data. Under these conditions, the Digital Terrain Model (DTM) of the SRTM project was included for plans related to the polygonal delimitation of the micro-basin, characterizing a drainage network, compartmentalization and mean slope.
Results: The natural vegetation of the Caatinga presents as open tree shrub and closed arboreal, with the predominance of open vegetation, representing 48037 ha (59.4%). Concerning conflict analysis for land use, it was observed that compartment 1 was the only one that did not present such events. Compartment 2 resulted in a higher percentage of conflicts with 24.1%, however, areas with 4.2% have agricultural divergences, the 19.9% are due to livestock and mining activities. In relation to compartment 3 the area 6.3% is used for agriculture.
Conclusion: The physical-conservationist diagnosis of the micro-basin of the river Farinha presents an incorrect management, for this, a suitable study must be done to reduce the degradation of the area. Consequently, public policies are designed to interconnect communities living in these areas with their physical environment in a sustainable way.
Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy
Authors: Mai Jiahui , Duan Jing , Chen Xiaoyu , Liu Liqin , Liang Dachao , Fu Tao , Lu Gang , Chan Wai Yee , Luo Xufeng , Wen Feiqiu , Liao Jianxiang , Li Zhuo , Lu Xinguo 
Published: November 2024

AbstractObjectiveApproximately 7% of individuals with dystrophinopathy remain undiagnosed at the genetic level using conventional genetic tests like multiplex ligation‐dependent probe amplification (MLPA) and next‐generation sequencing (NGS). We used the optical genome mapping (OGM) technology to detect and analyze uncommon mutations or structural variations (SVs) within the DMD gene, thus contributing to more precise clinical diagnoses.MethodsWe herein included eight patients with dystrophinopathy (six males and two females) in whom pathogenic variants of the DMD gene could not be accurately identified using MLPA and NGS. Clinical data were collected for all patients and genetic testing was performed using OGM.ResultsConventional methods (MLPA and NGS) failed to detect pathogenic mutations in six out of eight individuals (four males and two females). OGM testing uncovered rare mutations in the DMD gene in four patients, including a pericentric inversion in chromosome X (one male), a complex rearrangement (one male), and two X–autosome translocations (two females). No mutations were detected in the remaining two male patients. OGM also accurately mapped balanced X–autosome translocations in female patients, defining chromosomal breakpoints. In the other two male patients in whom MLPA suggested non‐contiguous exon duplications or deletions in the DMD gene, OGM characterized one case as a complex rearrangement and the other as a deletion within the DMD gene.InterpretationOGM is a valuable diagnostic tool for dystrophinopathy patients with negative results from conventional genetic tests. It can effectively elucidate complex SVs and pinpoint breakpoints in X–autosomal translocations in female patients, facilitating prompt and appropriate interventions.
3D Printing of Multiscale Biomimetic Scaffold for Tendon Regeneration
Authors: Yao Ke , Lv Shang , Zhang Xinjie , Shen Kangning , Chen Yuewei , Ma Zhiyong , He Yong 
Published: November 2024

AbstractMulti‐scale scaffolds with biomimetic extracellular matrix (ECM) structures are crucial for regenerative repair. Nevertheless, the intricate nature of nanostructures presents challenges when attempting to efficiently manufacture on a larger scale while maintaining bionics at the nanoscale. Here, a multiscale scaffold with hierarchical structures is designed to address these challenges, which can be biomimetic tendons from macro and micro to nanoscale. The multiscale biomimetic tendon (MBT) scaffold consists of a shell and core. The porous shell replicates the structure of a tendon sheath, offers mechanical support, and facilitates ease of sewing. The core scaffold comprises micro‐scale wave fibers with a nanohybrid Shish‐Kebab structure, designed to mimic the collagen fiber and fibril found in tendons. Additionally, the MBT scaffold demonstrates a strong tensile strength of 6.94 MPa and is shown to enhance the adhesion and proliferation of tendon stem/progenitor cells (TSPCs). Animal experiments have shown that the MBT scaffold can be surgically sutured in the tendon defect area to facilitate mechanical transduction and accelerate the regeneration of tendon tissue. The research combines the precise manufacturing of nano‐structures with efficient macro‐structure fabrication. It addresses the shortcomings of the disorder nanostructures and offers a fresh approach to creating multi‐scale bionic scaffolds.
Hybrid Cell Membrane‐Coated Nanoparticles for Synergizing Sonodynamic Therapy and Immunotherapy against Triple‐Negative Breast Cancer
Authors: Gong Jiali , Cheng Danling , Liu Changcun , Wu Shan , Sun Na , Zhao Lingzhou , Li Jingchao , Xing Yan , Zhao Jinhua 
Published: November 2024

AbstractTumor immunotherapy represents a highly promising modality for the treatment of triple‐negative breast cancer (TNBC). Nevertheless, its therapeutic efficacy has been profoundly impacted by challenges such as low drug uptake, hypoxia, and immunosuppression. To address these problems, the study develops a strategy combining sonodynamic therapy (SDT) and immunotherapy using biomimetic nanoparticles coated with hybrid membranes. The nanoparticles are loaded with semiconducting polymers (PFODBT), Atovaquone (ATO), and TMP195 to enhance biocompatibility, targeting ability, and drug uptake and retention at the tumor site. In in vitro experiments, the biomimetic nanoparticles alleviate hypoxia, induce immunogenic cell death (ICD), and prompt reprogramming of tumor‐associated macrophages (TAMs) from M2 type to M1 type. In in vivo experiments, the synergistic effects of enhanced SDT‐mediated ICD and TAMs repolarization significantly inhibit the proliferation of primary and distant tumor in the 4T1 subcutaneous tumor model, and effectively attenuated metastasis of lung and liver. Moreover, the in vivo immune responses are further activated by improving the maturation of dendritic cells, filtration of CD8+ T cells, and depletion of regulatory T cells. This study offers a novel strategy for TNBC therapy by converting the tumor microenvironment from the “cold” into “hot” tumor through multiple synergistic therapies.
Combined Photopolymerization and Localized Photochromism by Aza‐Diarylethene and Hemiindigo Synergy
Authors: Sacherer Maximilian , Dube Henry 
Published: November 2024

AbstractMolecular photoswitches produce light‐controlled changes at the nanometer scale and can therefore be used to alter the states and behavior of materials in a truly bottom‐up fashion. Here an escalating photonic complexity of material property control with light is shown using a recently developed aza‐diarylethene in combination with hemiindigo (HI) photoswitches. First, aza‐diarylethene can be used as a photoswitch in polystyrene (PS) to reversibly inscribe relief‐type 3D structures into PS. Second, aza‐diarylethene can further be used as a photoinitiator for light‐induced polymerization of methyl acrylate (MA), demonstrating for the first time light‐controlled chemical reactivity control with its zwitterionic switching state. Third, aza‐diarylethene and HIs are implemented into aza‐diarylethene polymerized MA, generating photochromic polymers. At the fourth level, a binary mixture allows to synergize aza‐diarylethene‐induced photopolymerization with localized photochromism changes of the simultaneously entrapped functional HI. With such multilevel light response, the utility of this particular photoswitch combination for applications in advanced photonic materials is demonstrated.
Aggregate Science: from Molecules, beyond Molecules
Authors: Ma Fulong , Zhang Siwei , Jiang Jinhui , Liu Yong , Sun Jianwei , Lam Jacky Wing Yip , Zhao Zheng , Tang Ben Zhong 
Published: November 2024

AbstractOver the past centuries, molecular science has played a dominant role in the advancement of physical science by exploring the structure–property relationships at a single molecular level. However, when molecules form aggregates, a dilemma arises as the structures and properties often differ significantly from those of molecular constituents. To address this, the concept of aggregate science emphasizes a holistic approach to understanding the structures–properties relationship of substances. Despite the recognition of holism in aggregate research, there are still challenges in investigating the complex operations and interplays, particularly in understanding the newly emergent structures and properties in the macroscopic world. Therefore, there is a need to further advance the concept and methodology. In this regard, this perspective highlights three types of influences that aggregation exerts on substance properties: activation, transformation, and emergence. Furthermore, examples from aggregation‐induced emission research and related fields are provided to illustrate how aggregate science can be studied. This perspective emphasizes that the molecule is of significance and the structures and properties are also dramatically influenced by aggregation. Additionally, potential research methodologies, such as focusing on intra‐ and intermolecular interactions, adjusting aggregates morphology, and regulating the constituents, along with directions, and implications are offered for future studies.