bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Struggling Trainee: Principles of Effective Remediation
Authors: Galetta Steven , Kurzweil Arielle 
Published: August 2018

AbstractStruggling trainees exist in all residency programs across all fields. Remediation, the act of improving deficiencies in struggling trainees, is necessary to promote the graduation of competent physicians. Deficiencies may be primarily cognitive or behavioral, and occasionally physical limitations do arise during residency. Remediation is challenging for all parties involved, and there is a paucity of literature to help guide the most effective process. In this review, we outline key principles of effective remediation of a struggling trainee in the modern era of medical education. A systematic approach that begins early, is consistent, and remains sensitive to a trainee's need for self-reflection in a nonjudgmental culture is essential for successfully remediating a trainee.
Blue Rubber Bleb Nevus Syndrome
Authors: Sullo Federica , D'Ambra Angela , Polizzi Agata , Garozzo Maria , Mendola Flavia , Pirrone Concetta , Commodari Elena , Schepis Carmelo , Lacarrubba Francesco , Micali Giuseppe , Quattrocchi Enrica , Zanghì Antonio , Ruggieri Martino , Praticò Andrea 
Published: August 2018

AbstractBlue rubber bleb nevus syndrome (BRBNS) is a rare congenital disorder characterized by multifocal venous malformations mainly of the skin, soft tissue, and gastrointestinal tract. However, it may occur in any tissue including the nervous system. This syndrome most commonly occurs sporadically but can be associated with an autosomal dominant inheritance. Among the cases reported in the literature, the female/male ratio was ∼1:1. The diagnosis of BRBNS is based on the presence of characteristic cutaneous lesions with or without gastrointestinal bleeding and/or the involvement of other organs. Typical skin manifestations consist of soft, easily compressive, bluish papules similar to rubber-like nipples. Aside the skin, vascular lesions are usually found in the gastrointestinal tract, anywhere from the oral to the anal mucosa, but predominantly in the small bowel. Endoscopy provides the opportunity to treat and diagnose the lesions. BRBNS should be differentiated from hereditary hemorrhagic telangiectasia (Osler–Weber–Rendu syndrome), Klippel–Trenaunay syndrome, and Maffucci syndrome. The prognosis of BRBNS depends on which organs are involved and the extent of involvement. Most patients can live a long life with the disease, but the quality of life is limited due to gastrointestinal bleeding, oral drug therapy, and blood transfusions. Sudden massive gastrointestinal hemorrhage remains the most frequent cause of death. No curative therapy is currently available for this syndrome. The cutaneous lesions are usually asymptomatic and do not require treatment. The most important clinical problem is the management of acute or chronic bleeding from the multiple gastrointestinal venous malformations: a conservative approach should be instituted whenever the clinical features and the bleeding episodes are mild and only in a life-threatening situation surgery may be required. In the recent years, however, molecular targeted therapy with the mammalian target of rapamycin inhibitor sirolimus has been anecdotally employed with reduction in bleeding and shrinkage of vascular malformations.
Rückkehr an den Arbeitsplatz nach depressiver Erkrankung - Evaluation einer retrospektiven Fall-Kontroll-Studie eines betriebsnahen integrierten Versorgungsmodells
Authors: Reifferscheid Alina , Wege Natalia , Riesbeck Mathias , Janssen Birgit 
Published: August 2018

ZusammenfassungZiel der Arbeit war die Evaluation eines betriebsnahen integrierten Versorgungsmodells (IGV) zur Optimierung der Behandlung depressiver Störungen. Es handelte sich um eine Kooperation zwischen einem Betrieb und einer externen Versorgungseinrichtung mit dem Ziel der Früherkennung, einem frühen Behandlungszugang sowie der Unterstützung bei der Rückkehr zur Arbeit. Methode: IGV-Patienten mit Depressionen (N=64) wurden mit einer parallelisierten Kontrollgruppe der Regelversorgung (N=64) retrospektiv verglichen. Die Evaluation erfolgte primär anhand der Messung der Rückkehr zur Arbeit. Ergebnisse: Patienten der IGV kehrten häufiger (Odds Ratio 11.9; p<0,001) und 91,2 Tage früher (p=0,010) an den Arbeitsplatz zurück als Patienten aus der Regelversorgung. Schlussfolgerung: Betriebsnahe IGV-Maßnahmen könnten die Zeit bis zur Wiederaufnahme der Arbeit verkürzen.
Silver-Impregnated Dressing Does Not Decrease Incidence of Surgical Site Infection after Adult Cardiac Surgery
Authors: Raman Vignesh , Thompson-Brazill Kelly A. , Kane Kathy , Harr Charles D. , Chaudhry Abdul G. , Merrill Hunter Robert , Boulton Bryon J. , Killinger William A. , Williams Judson B. 
Published: August 2018

Objective Sternal wound infections complicate 1% to 8% of cardiac surgeries and carry significant morbidity. We investigated the utility of silver-impregnated dressing in decreasing sternal wound infections after sternotomy cases. Methods A single-institution cohort study was performed as part of a quality improvement trial of a new sternal dressing. Five hundred fifty-seven sternotomy cases were performed in 2015 with application of a traditional gauze dressing. In 2016, 682 sternotomy cases were performed with the use of a commercially available silver-impregnated dressing. Prospectively identified metrics were analyzed for each patient population along with nursing assessments and structured questionnaires. Results Baseline characteristics of patients in traditional gauze and silver-impregnated dressing groups were similar. Morbidity and mortality were similar. Nine (1.6%) and 12 (1.8%) sternal wound infections were reported in traditional gauze and silver-impregnated dressing groups, respectively. There was no difference in the rate of sternal wound infections ( P = 0.80). The number of organ space infections (3) and deep sternal wound infections (3) was the same; however, the number of superficial infections was greater in the silver-impregnated dressing cohort (3 vs. 6). Among patients in either group with sternal wound infection, there were no differences in the proportion of superficial infections (44% vs. 50%, P = 0.8) or the organism cultured (67% vs. 50% staphylococcus, P = 0.45). A total of 22% of patients reported “not satisfied” with silver-impregnated dressing. Conclusions Silver dressings did not reduce sternal wound infection after sternotomy for cardiac surgery in a large-cohort study. We discontinued the routine use of silver dressings for adult cardiac surgery based on these results because traditional gauze likely represents an equally effective and less costly alternative.
Use of Systemic Antibiotics for Acute Otitis Externa: Impact of a Clinical Practice Guideline
Authors: Wang Xi , Winterstein Almut G. , Li Yan , Zhu Yanmin , Antonelli Patrick J. 
Published: August 2018

Objective:
To assess the extent of systemic antibiotic use among patients with acute otitis externa (AOE), as well as the impact of an AOE clinical practice guideline publication in 2006.

Study Design:
Interrupted time series study of retrospective data.

Setting:
Medicaid billing data from 29 states between 2002 and 2010.

Patients:
Patients with age less than 65 years, continuous Medicaid eligibility for 12 months before AOE diagnosis, and dispensation of antibiotics within 1 day before through 3 days after AOE diagnosis.

Main Outcome Measures:
The proportion of AOE visits that received systemic antibiotics among all AOE visits that were dispensed any antibiotics, systemic or topical.

Results:
We found 682,865 AOE visits that received systemic or topical antibiotics for AOE. The proportion of systemic antibiotic therapy either with or without topical therapy was 43.1% before and 38.3% after AOE guideline publication. There was no significant immediate drop (–0.01; 95%CI, –0.031–0.011) or change in trend (0.002; 95%CI, –0.001–0.004) in the prevalence of systemic antibiotic therapy after guideline publication.

Conclusion:
Publication of an AOE clinical guideline did not lead to a decline in systemic antibiotic therapy as initial AOE treatment. Additional efforts will be needed to curb systemic antibiotic treatment for AOE.
Can We Ameliorate Psychotic Symptoms by Improving Implicit Self-Esteem? A Proof-of-Concept Experience Sampling Study of an Evaluative Classical Conditioning Intervention
Authors: Espinosa Regina , Valiente Carmen , Varese Filippo , Bentall Richard P. 
Published: August 2018

Abstract
There is a need to develop novel interventions for psychosis, targeted at specific psychological mechanisms. We used a classical conditioning paradigm to a) modify implicit self-esteem and b) examine subsequent effects on subclinical psychotic symptoms measured by the Experience Sampling Methodology. This study is a proof-of-concept pilot investigation conducted with 28 students with high paranoia levels, assessing variations in their self-esteem, paranoid beliefs, and subclinical psychotic symptoms daily. After 2 days, participants were randomized to receive either a positive conditioning task (repeatedly pairing self-relevant words with an image of a smiling face) or a neutral conditioning task (repeatedly pairing self-relevant words with random smiling, angry, or neutral faces). After the intervention, the positive conditioning participants showed significantly higher levels of implicit self-esteem and lower subclinical psychotic symptoms than the control condition participants. This study demonstrated that implicit self-esteem can be increased by using a classical conditioning task.
Clinical Correlates of Cannabis Use Among Individuals With Attention Deficit Hyperactivity Disorder
Authors: Brandt Ariel , Rehm Jürgen , Lev-Ran Shaul 
Published: August 2018

Abstract
In this study, we explored patterns and clinical correlates of cannabis use among individuals with attention-deficit/hyperactivity disorder (ADHD). Data were obtained from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (2004–2005). Psychiatric disorders were assessed using the Alcohol Use Disorder and Associated Disabilities Interview Schedule. We used multivariate logistic regression models adjusting for sociodemographics, psychiatric disorders, and substance use disorders. Prevalence of cannabis use among individuals with and without ADHD was 14.3% and 4.3%, respectively. Diagnosis of any psychiatric disorder was significantly higher among those with ADHD and concurrent cannabis use compared with nonusers (adjusted odds ratio [AOR], 2.8; 95% confidence interval [CI], 1.08–6.41), as were odds of a lifetime personality disorder (AOR, 4.04; 95% CI, 1.84–8.84). Individuals with the hyperactive subtype initiated cannabis at a significantly earlier age compared with those with the inattentive subtype (13.8 ± 0.56 vs. 16.3 ± 0.5 years, respectively; p = 0.0017). Longitudinal prospective studies are required to further clarify the effects and patterns of cannabis use in this clinical population.
Quality control for community-based sea-ice model development
Authors: Roberts Andrew F. , Hunke Elizabeth C. , Allard Richard , Bailey David A. , Craig Anthony P. , Lemieux Jean-François , Turner Matthew D. 
Published: August 2018

A new collaborative organization for sea-ice model development, the CICE Consortium, has devised quality control procedures to maintain the integrity of its numerical codes' physical representations, enabling broad participation from the scientific community in the Consortium's open software development environment. Using output from five coupled and uncoupled configurations of the Los Alamos Sea Ice Model, CICE, we formulate quality control methods that exploit common statistical properties of sea-ice thickness, and test for significant changes in model results in a computationally efficient manner. New additions and changes to CICE are graded into four categories, ranging from bit-for-bit amendments to significant, answer-changing upgrades. These modifications are assessed using criteria that account for the high level of autocorrelation in sea-ice time series, along with a quadratic skill metric that searches for hemispheric changes in model answers across an array of different CICE configurations. These metrics also provide objective guidance for assessing new physical representations and code functionality.
This article is part of the theme issue ‘Modelling of sea-ice phenomena’.
Unstable Angina is a syndrome correlated to Th17 inflammatory disorder
Authors: Hu Wan-Chung 
Published: August 2018

AbstractPurposeUnstable angina is common clinical manifestation of atherosclerosis. However, the detailed pathogenesis of unstable angina is still not known. Here, I propose that unstable angina is a TH17 dominant inflammatory disorder.MethodsMicroarray dataset from unstable angina patients from Gene Expression Omnibus publicly available website is used for further analysis compared to healthy control.ResultsI find out that TH17 related cytokine, cytokine receptor, chemokines, complement, immune-related transcription factors, anti-bacterial genes, Toll-like receptors, and heat shock proteins are all up-regulated in peripheral leukocytes of unstable angina. In addition, H+-ATPase, glycolytic genes, platelet and RBC related genes are also up-regulated in peripheral leukocytes of during unstable angina. Pathway analysis also supports that TH17 immunological pathway is over-represented in the unstable angina dataset.ConclusionsThis finding implies that atherosclerosis is correlated to TH17 inflammatory disease. If we know the etiology of unstable angina as well as atherosclerosis better, we can have better methods to control and prevent this detrimental illness.
Accounting and political parties: explaining the “why” of an Italian light touch regulation (1974)
Authors: Gatti Marco , Poli Simone 
Published: August 2018

Purpose
The purpose of this paper is to explain the reasons why Law no. 195 of 2 May 1974, which established a system of public funding for the Italian political parties, introduced a system of controls that was light touch in nature.

Design/methodology/approach
The paper integrates the theoretical framework on regulatory space, proposed by Hancher and Moran (1989), with that of legitimacy (Suchman, 1995) to explain the peculiar nature of the system of controls introduced by the Law. Moreover, a set of primary and secondary sources is used to provide a full comprehension of the context, of the relationships among the actors involved in the regulatory process, and of the nature of the regulated issues.

Findings
Besides showing that the nature of the output of a regulatory process can be understood as the effect of the peculiar configuration of the regulatory space in which it takes place, the study also sheds light on the role that legitimation can play with regard to the other features of the regulatory space, namely on its ability to strengthen or to limit their effects on the output of the regulatory process.

Originality/value
The paper deals with accounting and political parties which is a much underexplored topic in the field of accounting history. In addition, from a theoretical standpoint it contributes to extending the theoretical framework by Hancher and Moran (1989).
Mental health of perpetrators of intimate partner violence
Authors: Sesar Kristina , Dodaj Arta , Šimić Nataša 
Published: August 2018

PurposeIntimate partner violence (IPV) represents a widespread social and public health problem. Researchers have been shown association between IPV and mental health problems. The purpose of this paper is to present a review of the literature on relationship between wide ranges of mental health problems.Design/methodology/approachResearch papers related to mental health problems among IPV perpetrators and published in leading academic journals in UK and abroad from 1987 to 2017 were identified and reviewed.FindingsAlthough there were some equivocal findings, the authors found that most of the available research suggests that there is a variety of psychological health problems among IPV perpetrators. Specifically, there was evidence of a significant relationship between anger problems, anxiety, depression, suicidal behaviour, personality disorders, alcoholism or problem gambling and perpetration of IPV. Results from analysed studies identified high rates of co-morbid disorders in IPV perpetrators.Practical implicationsThe findings highlight the need for treatment services to undertake screening and assessment of wide range of psychological difficulties to be able to provide best treatment approaches.Originality/valueTo the best of our knowledge, this is the first systematic review that has included studies evaluating various psychological health problems among perpetrators of IPV.
Club convergence analysis of regional ecological efficiency in China
Authors: Qiao Zhuo , Chen Hao 
Published: August 2018

AbstractThis paper adopts a network data envelopment analysis (DEA) model combined with a window analysis approach to evaluate the ecological efficiency (eco‐efficiency) of 30 regions in China over 2000–2015. We also investigate the existence of eco‐efficiency convergence clubs among these regions and analyse the important factors that drive eco‐efficiency club formation. Our results reveal that, overall, Chinese regional eco‐efficiency deteriorated from 2000 to 2015. We find that there is a significant regional disparity in eco‐efficiency. Our convergence analysis indicates that Chinese regions converge into three eco‐efficiency clubs, suggesting that common economic and environment policies might have a limited impact on promoting regional eco‐efficiency and regionally‐tailored policies need to be designed. Finally, we find that forest coverage, R&D expenditure and pollution punishment are important determinants of convergence club membership.
Comparative Evaluation of Five Different Methods of Anti‐ABO Antibody Titration: An Aid for ABO‐Incompatible Organ Transplants
Authors: Nayak Sweta , Makroo Raj Nath , Prakash Bindu , Chandra Trilok , Agrawal Soma , Chowdhry Mohit , Mohapatra Archisman 
Published: August 2018

AbstractThe accurate estimation of ABO antibody titers is of the utmost importance in organ transplants involving ABO incompatibility. We aim to compare five different methods of titration and analyze the data. Samples of 48 O group blood donors who donated during the month of December 2015 to January 2016 in our institution were subjected to ABO antibody titration by five different methods: immediate spin (IS) tube titer, antihuman globulin phase tube titer, Coomb's gel card titer, gel card titer after dithiotreitol (DTT) treatment of plasma, and the solid phase red cell adherence method. The mean number of titer serial dilution steps in the different titer estimation methods was compared using the paired t‐test and McNemar test. A correlation between the methods was tested using Spearman's rho and kappa statistics. The median antiglobulin (AHG) phase tube titers were found to be the highest anti‐A (128) and anti‐B (192) titers. Significant differences in the ABO antibody titer readings among the five different methods were noted. Titers were reduced by DTT treatment in nearly 50% samples tested for both anti‐A and anti‐B titers. Average agreements between the DTT‐applied AHG phase gel card titers and the solid phase red cell adherence (SPRCA) titers was observed for anti‐A (κ = 0.473) and anti‐B (κ = 0.530). The AHG phase tube and gel cards titers showed poor agreements. There are differences in the interpretability of the ABO antibody titer among different techniques. Consistent and uniform application of the method for titration throughout the treatment of a patient is highly essential.
Exploring individual differences in self‐reference effects for agency and ownership in 5‐ to 7‐year‐olds
Authors: Ford Ruth M. , Lobao Sheila N. 
Published: August 2018

Evidence that self‐relevant information enjoys a privileged status in memory is termed the self‐reference effect (SRE). Testing 5‐to 7‐year‐olds (n = 39), we aimed to shed light on the SRE by examining the memorial advantage for self‐relevant information as a function of general ability, theory of mind, empathy, and recollection. Playing in pairs, children were presented with an array of pictures and took turns to select pictures (agency) and turn them over to reveal to whom they belonged (ownership). Later, they viewed the studied pictures intermixed with new ones and provided recognition‐ and source memory judgements. There was a robust SRE in recognition memory, mainly for agency, which varied positively with intellectual ability but negatively with theory of mind, empathy, and recollection. These findings accord with claims that self‐referential information benefits from elaboration handled by domain‐general processes, with the SRE counteracted by social processes that increase attention to other people.
Statement of Contribution

What is already known on this subject?

Self‐referential information is remembered better than information with little or no personal relevance (the self‐reference effect or SRE)

Children as young as 4 years show the SRE in tests of recognition‐ and source memory

What does this study add?

We explored individual differences variables correlated with the SRE in 5–7 year olds

The SRE showed a positive relation with general intellectual ability but negative relations with empathy, theory of mind and recollection

We suggest that self‐referential information benefits from elaboration handled by domain‐general processes, with the SRE counteracted by social processes that increase attention to other people
Subleukaemic acute myeloid leukaemia with myelodysplasia in a horse
Authors: Miglio A. , Pepe M. , Felippe M. J. B. , Antognoni M. T. 
Published: August 2018

SummaryAcute myeloid leukaemia (AML) is rarely reported in horses and myelodysplastic syndrome (MDS) has been described only in one case. Acute myeloid leukaemia is defined as the presence of at least 20% blasts in the marrow or blood. On the other hand, MDS is characterised by morphologic abnormalities in one or more cell lineages with hypercellular marrow and peripheral cytopenias due to ineffective haematopoiesis. We report a case of acute myelomonocytic leukaemia with myelodysplasia‐related features in a horse. A supposed diagnosis was based on abnormal morphology of circulating neoplastic cells and bone marrow cytology. A final diagnosis was made by using flow cytometry (FC) in conjunction with cytochemistry (CC) rarely reported in the haematopoietic neoplasms of the horse.