bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inland-coastal bifurcation of southern East Asians revealed by Hmong-Mien genomic history
Authors: Xia Zi-Yang , Yan Shi , Wang Chuan-Chao , Zheng Hong-Xiang , Zhang Fan , Liu Yu-Chi , Yu Ge , Yu Bin-Xia , Shu Li-Li , Jin Li 
Published: August 2019

ABSTRACTThe early history of the Hmong-Mien language family and its speakers is elusive. A good variety of Hmong-Mien-speaking groups distribute in Central China. Here, we report 903 high-resolution Y-chromosomal, 624 full-sequencing mitochondrial, and 415 autosomal samples from 20 populations in Central China, mainly Húnán Province. We identify an autosomal component which is commonly seen in all the Hmong-Mien-speaking populations, with nearly unmixed composition in Pahng. In contrast, Hmong and Mien respectively demonstrate additional genomic affinity to Tibeto-Burman and Kra-Dai speakers. We also discover two prevalent uniparental lineages of Hmong-Mien speakers. Y-chromosomal haplogroup O2a2a1b1a1b-N5 diverged ∼2,330 years before present (BP), approximately coinciding with the estimated time of Proto-Hmong-Mien (∼2,500 BP), whereas mitochondrial haplogroup B5a1c1a significantly correlates with Pahng and Mien. All the evidence indicates a founding population substantially contributing to present-day Hmong-Mien speakers. Consistent with the two distinct routes of agricultural expansion from southern China, this Hmong-Mien founding ancestry is phylogenetically closer to the founding ancestry of Neolithic Mainland Southeast Asians and present-day isolated Austroasiatic-speaking populations than Austronesians. The spatial and temporal distribution of the southern East Asian lineage is also compatible with the scenario of out-of-southern-China farming dispersal. Thus, our finding reveals an inland-coastal genetic discrepancy related to the farming pioneers in southern China and supports an inland southern China origin of an ancestral meta-population contributing to both Hmong-Mien and Austroasiatic speakers.
Escape mutations circumvent a tradeoff between resistance to a beta-lactam and a beta-lactamase inhibitor
Authors: Russ Dor , Glaser Fabian , Tamar Einat Shaer , Yelin Idan , Zampaloni Claudia , Haldimann Andreas , Kishony Roy 
Published: August 2019

AbstractBeta-lactamase inhibitors are increasingly used to counteract microbial resistance to beta-lactam antibiotics mediated by beta-lactamase enzymes. These inhibitors compete with the beta-lactam drug for the same binding site of the beta-lactamase, thereby generating an inherent evolutionary tradeoff: enzyme mutations that increase its activity against the beta-lactam drug also increase its susceptibility towards the inhibitor. It is unclear how common and accessible are mutants that escape this adaptive tradeoff. Here, systematically constructing and phenotyping a deep mutant library of theampCbeta-lactamase gene ofEscherichia coli, we identified escape mutations, which even in the presence of the enzyme inhibitor allow growth at beta-lactam concentrations far exceeding the native inhibitory levels of the wildtype strain. Importantly, while such escape mutations appear for combinations of avibactam with some beta-lactam drugs, for other drugs escape phenotypes are completely restricted. Amplicon sequencing of the selected mutant pool identified these escape mutations and showed that they are rare and drug specific. For the combination of avibactam with aztreonam, an escape phenotype was conferred via multiple substitutions in a single conserved amino acid (Tyr 150). In contrast, a different set of mutations showed an escape phenotype for cefepime, and no escape mutants appeared for piperacillin. The differential adaptive potential ofampCto combinations of avibactam and different beta-lactam drugs can help guide drug treatments that are more resilient to evolution of resistance.
Escherichia coli Metabolite Profiling Leads to the Development of an RNA Interference Strain for Caenorhabditis elegans
Authors: Neve Isaiah A. A. , Sowa Jessica N. , Lin Chih-Chun J. , Sivaramakrishnan Priya , Herman Christophe , Ye Youqiong , Han Leng , Wang Meng C. 
Published: August 2019

AbstractThe relationship of genotypes to phenotypes can be modified by environmental inputs. Such crucial environmental inputs include metabolic cues derived from microbes living together with animals. Thus the analysis of genetic effects on animals’ physiology can be confounded by variations in the metabolic profile of microbes. Caenorhabditis elegans exposed to distinct bacterial strains and species exhibit phenotypes different at cellular, developmental and behavioral levels. Here we reported metabolomic profiles of three Escherichia coli strains, B strain OP50, K-12 strain MG1655, and B-K-12 hybrid strain HB101, and also different mitochondrial and fat storage phenotypes of C. elegans exposed to MG1655 and HB101 versus OP50. We found that these metabolic phenotypes of C. elegans are not correlated with overall metabolic patterning of bacterial strains, but their specific metabolites. In particular, the fat storage phenotype is traced to the betaine level in different bacterial strains. HT115 is another K-12 E. coli strain that is commonly utilized to elicit an RNA interference response, and we showed that C. elegans exposed to OP50 and HT115 exhibit differences in mitochondrial morphology and fat storage levels. We thus generated an RNA interference competent OP50 (iOP50) strain that can robustly and consistently knockdown endogenous C. elegans genes in different tissues. Together, these studies suggest the importance of specific bacterial metabolites in regulating the host’s physiology, and provide a tool to prevent confounding effects when analyzing genotype-phenotype interactions under different bacterial backgrounds.
Investigation of the effect of second phase precipitates on the corrosion and electrical conductivity of 7075 aluminum alloys
Authors: Şimşek Ijlal 
Published: August 2019

PurposeThis paper aims to investigate the effects of second phase precipitate size on microstructure, hardness, density, corrosion and electrical conductivity of 7075 aluminum alloy fabricated by the powder metallurgy method and aged at 120°C for various aging periods.Design/methodology/approachFor the aging process (T6), these alloys were solution-treated at 485°C for 2 h, quenched, aged at 120°C for four various periods and finally air cooled. After the aging process, these alloys were examined with scanning electron microscope, X-ray diffraction, density and hardness measurements. The corrosion tests were carried out using the potentiodynamic polarization technique; electrical conductivity values were measured as IACS%.FindingsResults showed that the precipitate size increased with increasing aging period and the maximum precipitate size was achieved for the sample aged for 28 h. The maximum hardness was attained for the sample aged for 24 h, while the same specimen obtained the lowest electrical conductivity and corrosion resistance.Originality/valueIn this research, second phase precipitates of heat treatment processing affected the electrical conductivity and corrosion behavior of the 7075 aluminum alloy. Also it is understood that the heat treatment period is an effective parameter on these properties.
Mild steel protection with tannic and polyaspartic acid in cooling systems
Authors: Sezer Esma , Öztürk İpek 
Published: August 2019

Purpose
Tannic acid (TA) is one of the green corrosion inhibitors for mild steel; its anti-corrosive performance in alkaline water on mild steel when it is used together with polyaspartic acid (PASA) still has not been investigated. The purpose of this study is to develop an effective, biodegradable and environment-friendly novel corrosion inhibitor based on TA and PASA as an alternative to the conventional inorganic inhibitors for mild steel in decarbonised water, which is common in cooling systems.

Design/methodology/approach
Corrosion inhibition mechanism is investigated by electrochemical techniques such as polarisation measurements and electrochemical impedance spectroscopy, and results were evaluated to determine the optimum inhibitor concentration for industrial applications. Additionally, practice-like conditions are carried out in pilot plant studies to simulate the conditions in cooling systems. Thus, the efficiencies of the inhibitors are evaluated through both weight loss and linear polarisation resistance measurements. Moreover, the corrosion product is characterised by scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDX) and Fourier-transform infrared spectroscopy (FTIR) analysis.

Findings
TA shows high inhibition efficiency especially towards pitting corrosion for mild steel in decarbonised water. PASA addition in the cooling systems improves the inhibition efficiency of TA, and at lower concentrations of TA + PASA, it is possible to obtained better inhibition efficiency than TA alone at higher inhibitor amounts, which is essential in economic and environmental aspect.

Originality/value
A blended inhibitor program including TA and PASA with suggested concentrations in this work can be used as an environmental friendly treatment concept for the mild steel corrosion inhibition at cooling systems.
Trends of puffery in advertising – a bibliometric analysis
Authors: Punjani Krunal K. , Ravi Kumar V.V. , Kadam Sanjeev 
Published: August 2019

Purpose
The purpose of this paper is to quantitatively assess the essential trends of existing research on “puffery in advertising” through bibliometric analysis.

Design/methodology/approach
This study uses citation data collected through Scopus and Google Scholar for the research area “puffery in advertising” to investigate the most productive journals, top countries of affiliation and prominent years with maximum citations. The study analyses the 87 articles related to “puffery in advertising,” published during 1840 to 2018. Moreover, this study also presents graphical analysis through network maps.

Findings
“Puffery in advertising” has remained an under-researched area. However, records of past ten years indicate marginal growth in the number of publications. USA dominates this research area with most numbers of articles published till date. Through clustering of subject areas, it is found that majority of articles have been published under the subject area of “Business, Management and Accounting.” Interestingly, the results of the network maps slightly differ from that of citation table.

Practical implications
This paper is useful for any reader or researcher who wants to understand the trends of “puffery in advertising” in terms of citation analysis, authors and affiliation countries, and prominent years with maximum citations, which would further enable them to discover emerging research areas, potential research collaborations and publications.

Originality/value
To the knowledge of the authors, this is the first ever bilbiometric study on “puffery in advertising” providing a bird’s-eye view of the essential trends.
The triple-As supply chain competitive advantage
Authors: Feizabadi Javad , Gligor David , Alibakhshi Motlagh Somayeh 
Published: August 2019

PurposeThe purpose of this paper is to draw on resource orchestration theory (ROT) and resource advantage theory (RAT) to develop a measurement scale for supply chain competitive advantage (SCCA) as a second-order construct with the dimensions of agility, adaptability and alignment (triple-A).Design/methodology/approachA survey research design is adopted to collect primary and secondary data from 182 international firms. The paper utilizes a scale development procedure to develop a measurement instrument and assess its psychometric properties. The scale’s predictive validity is tested using both subjective and objective data. Additionally, the simultaneous effect of triple-A is tested using latent congruent modeling.FindingsDrawing upon ROT and RAT, this study introduces SCCA as a second-order construct composed of SC agility, adaptability and alignment. In addition, the findings show that an SCCA has a direct and positive impact on firms’ financial and market performance.Originality/valueExisting literature indicates that competition has shifted from inter-firm to inter-SC. To account for this change in competition level, past studies have suggested various capabilities that SCs must possess to offer a competitive advantage, such as triple-As. However, drawing upon RAT and ROT, the authors argue that the SCCA construct accounts for sources of advantage in both the resource side and the demand side. The authors further assert that possessing supply chain resources (i.e. agility, adaptability, alignment as disparate resources) is not sufficient to create advantage but the resources must be orchestrated to create SCCA (i.e. the combination of agility, adaptability and alignment).
Qualitative research with primary school-aged children: ethical and practical considerations of evaluating a safeguarding programme in schools
Authors: Jackson-Hollis Vicki 
Published: August 2019

PurposeThe purpose of this paper is to explore some of the ethical and practical challenges of working with primary school-aged children to conduct qualitative service evaluations regarding sensitive safeguarding topics.Design/methodology/approachThe paper centres on the author’s learnings from conducting school-based, task-assisted focus groups with 5–11 year olds. The reflections are drawn from notes made during fieldwork, debrief discussions with evaluation colleagues and wider team debates. This was a consultative participatory evaluation and the findings are situated within the wider literature around rights-based approaches to research.FindingsUsing multi-method and creative approaches can facilitate young children to assent and dissent from service evaluation in a school setting. However, the challenges of helping children understand confidentiality are highlighted, as is the challenge for researchers in recognising and respondingin situto disclosures. Using suitable and creative activities, this evaluation demonstrates that primary school children can contribute meaningful data to assist with service development. However, the approach to collecting these data from the youngest children needs careful consideration.Practical implicationsResearchers may need to adopt full participatory methods to better help children understand the confidentiality bounds of research and to form views on the subject matter. More discussion is needed in the wider safeguarding research literature to show how researchers have navigated the challenges of handling disclosures.Originality/valueThis paper contributes to the literature by providing examples of how to overcome issues of children’s participation, consent and protection in service evaluation focussed on a sensitive topic.
You Shall (Not) Fear
Authors: Lim Heejin , Cho Moonhee , Bedford Sergio C. 
Published: August 2019

Purpose
In the age of transparency, nonprofit organizations have attempted to raise awareness of unethical business practices through diverse social media platforms, putting firms under great pressure to incorporate sustainability in their operations. Focusing on the issue of animal cruelty which is a relatively under-investigated topic in the fashion industry, the purpose of this paper is to examine how different levels of animal cruelty depicted in nonprofit organizations’ ethical consumption campaigns influence viewers’ negative emotions and lead to their supportive behavior and ethical consumption intention.

Design/methodology/approach
In the main study, undergraduate students (n=82) from a big public University in the USA were recruited in exchange for extra credit and randomly assigned to one of the three experimental conditions of animal cruelty in a single-factor, three-level, between-subjects experimental design: non-threatening condition (n=26), low-threatening condition (n=27) and high-threatening condition (n=29).

Findings
The results indicated that the levels of negative emotional arousal are positively related to levels of perceived animal cruelty in social media campaigns. In addition, negative emotional arousal mediates the effect of perceived animal cruelty on the intention of supportive behavior, but no mediation effect on ethical consumption intention was found. Additionally, the findings of this study revealed that the indirect effect of perceived animal cruelty on supportive behavior intention is moderated by participants’ moral justification such as the reality of economic development and government dependency.

Originality/value
The findings of this study contribute to the literature by advancing the current understanding of the role of negative emotional images in ethical consumption campaigns in the context of animal cruelty in the fashion industry.
Leader–follower narcissism and subgroup formation in teams: a conceptual model
Authors: London Manuel 
Published: August 2019

Purpose
Drawing on existing theory, a model is developed to illustrate how the interaction between leaders and followers similarity in narcissism and goal congruence may influence subgroup formation in teams, and how this interaction influences team identification and team performance.

Design/methodology/approach
The proposed model draws on dominance complementary, similarity attraction, faultline formation and trait activation theories.

Findings
Leader–follower similarity in narcissism and goal congruence may stimulate subgroup formation, possibly resulting in conformers, conspirators, outsiders and victims, especially when performance pressure on a team is high. Followers who are low in narcissism and share goals with a leader who is narcissistic are likely to become conformers. Followers who are high in narcissism and share goals with a narcissistic leader are likely to become confederates. Followers who do not share goals with a narcissistic leader will be treated by the leader and other members as outsiders if they are high in narcissism, and victimized if they are low in narcissism. In addition, the emergence of these subgroups leads to reduced team identification and lower team performance.

Practical implications
Higher level managers, coaches and human resource professions can assess and, if necessary, counteract low team identification and performance resulting from the narcissistic personality characteristics of leaders and followers.

Originality/value
The model addresses how and under what conditions narcissistic leaders and followers may influence subgroup formation and team outcomes.
Helping a depressed Chinese adult with high functioning autism reconnect with his family through structural family therapy
Authors: Ma Joyce L. C. , Wong Chi‐yan , Xia Lily L. L. 
Published: August 2019

This clinical case example from a Chinese context describes the healing journey through structural family therapy (SFT) of a depressed Chinese father with high functioning autism (HFA). The paper both narrates the experience of a father and his family in facing the relational challenges arising from HFA and explores the contributions of SFT in helping. Identifying the father’s history of loss at the individual and family levels as well as the pattern of family relationships in the family sheds light on directions for treatment. Key treatment principles of SFT and strategies to help depressed adults with HFA let go of anger and losses, both symbolic and real, and reconnect with their families are discussed.Practitioner points

Structural family therapy (SFT) can assist depressed adults with high functioning autism (HFA) in reconnecting with their spouses and children

Therapists’ trust of family competence and uniqueness, and the artful use of enactment, can facilitate healing for depressed adults with HFA

Therapists’ knowledge of HFA, and their humility and willingness to learn from this clientele, are critical
Spillover Effects of Capital Expenditure Announcements Within Business Groups
Authors: Chen I‐Fen , Chang Shao‐Chi 
Published: August 2019

AbstractUsing the capital expenditure announcements of Taiwanese business group affiliated firms, this study examines whether the group diversification and ownership structure influence intragroup spillover effects. We find that the stock price reactions of the announcing firms are positively associated with both the stock price reactions and the post‐announcement long‐term performance of their non‐announcing group peers. More importantly, the evidence shows that this positive spillover effect weakens for business groups associated with a pyramidal ownership structure. The evidence supports the conjecture that principal–principal conflicts play an important role in moderating the spillover effects in a business group. The findings further show that the spillover effects are stronger during periods of financial crises. Finally, in the 3‐year period following announcements, the non‐announcing group members experience declining industry‐adjusted performance.
Accelerating the United Nation's 2030 Global Agenda: Why Prioritization of the Gender Goal is Essential
Authors: Hepp Paula , Somerville Claire , Borisch Bettina 
Published: August 2019

AbstractIn September 2015, Member States of the United Nations (UN) committed to work towards a transformative policy agenda consisting of 17 ambitious Sustainable Development Goals (SDGs) to be achieved by 2030. However, implementation progress has been slow and at the current rate the SDG agenda will fall far short on delivery of its 169 targets. In order to accelerate progress at global, national and local levels it is necessary to prioritize goals and targets. One standalone SDG that is also cross‐cutting and universal is Goal 5: Gender equality and empowerment of all women and girls. In this article we assemble evidence to make the case that decisively (and politically) placing the gender equality goal (SDG5 and its 9 targets) together with 54 gender indicators across all goals as the priority focus of the 2030 agenda is the most impactful way to ensure measurable achievements are made across the agenda to deliver on all 5 pillars of the global commitment: namely People, Planet, Peace, Prosperity and Partnerships.
Patients with inflammatory bowel disease have an increased risk of myocardial infarction: a nationwide study
Authors: Choi Yoon Jin , Lee Dong Ho , Shin Dong Woo , Han Kyung‐Do , Yoon Hyuk , Shin Cheol Min , Park Young Soo , Kim Nayoung 
Published: August 2019

SummaryBackgroundInflammatory bowel disease (IBD) is accompanied by various extraintestinal manifestations including systemic inflammation and hypercoagulability, which may increase the risk of atherosclerosis and ischaemic heart disease.AimTo investigate whether IBD is associated with an increased risk of myocardial infarction (MI), stroke or deathMethodsThe International Classification of Disease, 10th edition codes and the claim codes for rare diseases were used to identify candidates from National Health Insurance Service (NHIS) of South Korea. Patients diagnosed with Crohn's disease (CD) or ulcerative colitis (UC) between 2006 and 2009 were age‐matched 1:3 with NHIS enrolees without IBD. The primary outcomes included newly developed MI, stroke and death. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using Cox regression models.ResultsWe identified 10 708 patients diagnosed with CD and 26 769 with UC. MI risk was higher in CD patients than in controls (incidence ratio (IR) 1.64 per 1000 person‐years, HR, 1.80; 95% CI, 1.47‐2.21), and this trend was more prominent among patients aged <40 years (IR 0.69 per 1000 person‐years, HR, 2.96; 95% CI, 1.96‐4.47) and among female patients (IR 2.35 per 1000 person‐years, HR, 2.18; 95% CI, 1.61‐2.94). In contrast, only female patients with UC had an increased risk of MI (IR 2.01 per 1000 person‐years, HR, 1.33; 95% CI, 1.13‐1.56).ConclusionsThe risk of MI risk is higher in patients with CD than in the general population, and this trend is stronger in female patients and those aged <40 years.