bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating reimbursement of integrated support services using chronic care management (CCM) codes for treatment of hepatitis C among Medicare beneficiaries
Authors: Fluegge Kyle , Bresnahan Marie P. , Laraque Fabienne , Litwin Alain H. , Perumalswami Ponni V. , Shukla Shuchin J. , Weiss Jeffrey J. , Winters Ann 
Published: August 2019

AbstractThe New York City Department of Health and Mental Hygiene (DOHMH) implemented Project INSPIRE, an integrated model of hepatitis C care coordination and telementoring services, from 2014 to 2017. We evaluated the use of chronic care management (CCM) codes to sustain the intervention. DOHMH data were collected as part of a Healthcare Innovation Award from the Centers for Medicare & Medicaid Services (CMS). A retrospective cohort medical billing study was conducted by assigning INSPIRE activities to procedure codes in both facility and nonfacility settings. Rates for procedures were extracted from the CMS's 2018 fee schedules and added across the eligibility periods for Medicare enrollees. Reimbursement was adjusted on the basis of expected patient attrition and compared to costs. The minimum number needed to treat (NNT) to break even was calculated in each setting. Facility reimbursement was higher than costs, whereas nonfacility reimbursement was lower (both P < .01). The NNT was 23 patients in facilities and 33 patients in nonfacilities; 24 patients per care coordinator were treated annually in INSPIRE. CCM fees alone were insufficient to fully reimburse the costs in either setting. Implementation of an appropriate risk financing strategy is necessary to mitigate financial shortfalls when providing CCM services in facility settings.
A novel CEM technique for modeling electromagnetic scattering from metasurfaces
Authors: Ozgun Ozlem , Mittra Raj , Kuzuoglu Mustafa 
Published: August 2019

AbstractThis paper presents a novel computational electromagnetics (CEM) technique, which hybridizes the periodic finite element method (FEM) with the method of moments (MoM), for efficient numerical modeling of electromagnetic scattering from metasurfaces consisting of truncated periodic or locally varying quasi‐periodic array of structures. Based on the quasi‐periodic nature of metasurfaces, the periodic FEM is employed to generate high‐level macro basis functions (MBFs). Following that, a reduced MoM matrix is formed by using the MBFs with unknown coefficients belonging to each cell of the periodic array. The proposed hybrid method reduces the computational load significantly when compared with conventional numerical methods, especially for electrically large truncated metasurfaces involving arbitrarily inhomogeneous unit cells. Various numerical results are presented, and the accuracy and performance of the proposed method are tested against commercial codes, as well as an in‐house FEM code.
Changes in winter stationary wave activity during weak mid‐latitude and Arctic thermal contrast period
Authors: Wang Sai , Nath Debashis , Chen Wen , Wang Lin 
Published: August 2019

AbstractUsing reanalysis data set, this study investigates the changes in winter mean stationary wave activity, when the thermal contrast between mid‐latitude and Arctic is weak. The mid‐latitude and Arctic thermal contrast was stronger during 1986–2003 and weaker during 1966–1985 and 2004–2017. The changes in stationary wave characteristics are studied based on the stationary wave activity flux (SWAF). Compare to the period when the contrast was stronger (1986–2003), both the convergence of SWAF and stationary wave amplitude have been enhanced in the Northern part of Eurasia during the periods 1966–1985 and 2004–2017. We further proposed that a weak mid‐latitude/Arctic thermal contrast provides a good condition for the enhancement of the stationary wave activity. The weak mid‐latitude‐Arctic thermal contrast is conducive to the enhancement of blocking frequency around Ural Mountains, which may contribute partly to the increase in stationary wave amplitude and associated changes in the SWAF. Furthermore, the weak thermal contrast is associated with the decrease in baroclinicity and synoptic‐scale eddy activity, which in turn contributes to the generation of stationary waves via eddy feedback processes.
Improving visual biodiversity assessments of motile fauna in turbid aquatic environments
Authors: Jones Robyn E. , Griffin Ross A. , Rees Sam C. , Unsworth Richard K.F. 
Published: August 2019

AbstractCurrent knowledge of turbid coastlines relies heavily on extractive sampling methods with less destructive visual techniques limited primarily by underwater visibility. Baited Remote Underwater Video (BRUV) is now a commonly used nonextractive sampling technique which involves the use of bait to attract motile fauna to the field of view of the camera, but its use is restricted to clear water environments. Here, we describe and test the addition of a clear liquid optical chamber (CLOC) to a BRUV system to improve underwater visibility when observing motile fauna in turbid waters. The CLOC method was trialed with respect to the ability of the system to identify taxa to species level in both controlled laboratory and field conditions across gradients of underwater visibility. This study found that the introduction of a CLOC to a conventional BRUV system significantly improved the ability to observe identifying features of four fish species in a controlled low‐visibility environment (p ≤ 0.001). The ability to identify taxa to species level in field conditions was also significantly increased with the addition of a CLOC (p ≤ 0.01). We conclude that the introduction of a CLOC to a conventional BRUV system is a reliable way of improving underwater visibility when assessing motile fauna allowing for a more consistent identification of taxa to species level. This system may be applied to both marine and freshwater aquatic environments.
Rare single‐nucleotide variants in oculo‐auriculo‐vertebral spectrum (OAVS)
Authors: Zamariolli Malú , Colovati Mileny , Moysés‐Oliveira Mariana , Nunes Natália , Caires dos Santos Leonardo , Alvarez Perez Ana B. , Bragagnolo Silvia , Melaragno Maria Isabel 
Published: August 2019

AbstractBackgroundOculo‐auriculo‐vertebral spectrum (OAVS) is a craniofacial developmental disorder that affects structures derived from the first and second pharyngeal arches. The clinically heterogeneous phenotype involves mandibular, oral, and ear development anomalies. Etiology is complex and poorly understood. Genetic factors have been associated, evidenced by chromosomal abnormalities affecting different genomic regions and genes. However, known pathogenic single‐nucleotide variants (SNVs) have only been identified in MYT1 in a restricted number of patients. Therefore, investigations of SNVs on candidate genes may reveal other pathogenic mechanisms. MethodsIn a cohort of 73 patients, coding and untranslated regions (UTR) of 10 candidate genes (CRKL, YPEL1, MAPK1, NKX3‐2, HMX1, MYT1, OTX2, GSC, PUF60, HOXA2) were sequenced. Rare SNVs were selected and in silico predictions were performed to ascertain pathogenicity. Likely pathogenic variants were validated by Sanger sequencing and heritability was assessed when possible.ResultsFour likely pathogenic variants in heterozygous state were identified in different patients. Two SNVs were located in the 5’UTR of YPEL1; one in the 3’UTR of CRKL and one in the 3’UTR of OTX2.ConclusionOur work described variants in candidate genes for OAVS and supported the genetic heterogeneity of the spectrum.
An Importance–Satisfaction Analysis of Trout License Holders in Georgia
Authors: TenHarmsel Hailey J. , Boley B. Bynum , Irwin Brian J. , Jennings Cecil A. 
Published: August 2019

Abstract
As anglers become increasingly diverse, fisheries managers are challenged to find ways to satisfy users with divergent preferences while conserving a limited resource on a limited budget. With this management challenge in mind, this study combines previous angler specialization research with an importance–satisfaction analysis (ISA) to aid fisheries managers in better understanding users with divergent preferences. An ISA involves asking stakeholders to simultaneously evaluate the importance of salient attributes of their fishing experience and their satisfaction with those attributes, which allows for graphical depiction of each attribute in one of four quadrants with managerial implications: Concentrate Here, Keep up the Good Work, Possible Overkill, and Low Priority. The data were collected via a mail-administered survey that was sent to 4,000 licensed trout anglers who were residents of Georgia. The anglers were asked to evaluate 10 catch and 7 noncatch attributes as well as answer questions that were used to measure levels of angler specialization. A K-means cluster analysis was used to segment the 469 respondents into three groups based on their specialization level. Analysis of variance (ANOVA) was used to determine whether anglers’ preferences differed by level of specialization. The results revealed that specialization groups differed in the level of importance that they placed on 6 catch and 4 noncatch attributes and in their levels of satisfaction with 5 catch and 2 noncatch attributes. There were also differences among the groups in quadrant placement for both catch and noncatch attributes. The respondents agreed that habitat improvement initiatives, adding new fishable water, and clear signage of regulations were of relatively high importance, with habitat improvement initiatives as the only attribute to fall in the Concentrate Here quadrant for all three clusters. The average responses for importance and satisfaction were highest for the most specialized group and lowest for the least specialized group. Combining segmenting techniques, like cluster analysis with ISA, offers fisheries managers the opportunity to gauge different user groups’ perceptions of salient fishery attributes.
CASA‐IoT: Scalable and context‐aware IoT access control supporting multiple users
Authors: Castro Tiago O. , Caitité Vitor G. R. , Macedo Daniel F. , dos Santos Aldri L. 
Published: August 2019

SummaryThe Internet of Things (IoT) supports many users and context‐aware applications controlling heterogeneous IoT devices. This differs from traditional networks, in which a single entity manages each device. Thus, new access control models must be created in order to support more responsive, scalable, secure, and autonomous management. This article presents an attribute‐based access control model, which applies conflict resolution and access delegation in a multiuser and multiapplication environment. With scalability in mind, we propose the caching of access permissions, as well as a split policy processing model in which the devices with enough computational power perform part of the processing. The proposed model was implemented as part of the ManIoT architecture an d evaluated in experiments on a testbed to demonstrate its efficiency. Results show that our model accelerates the processing of access management policies from 51% by up to 79%.
Addressing the big picture: Deaf children and reading assessments
Authors: Greene‐Woods Ashley , Delgado Natalie 
Published: August 2019

AbstractIn the field of education, there is a great emphasis placed on literacy, from reading fluency to writing. There are various approaches that teachers can use in their classroom to design and identify needed areas of instruction, but these approaches do not always apply to Deaf Education. The act of using the same assessments throughout all student populations presents some potential issues, particularly the question of whether or not the students’ actual literacy abilities are being identified. The focus is to spotlight a frequently used approach for measuring reading fluency and present an alternative approach.
Conjugate addition between syringol and a captodative olefin catalyzed by BF3
Authors: Morales‐Palacios Freddy G. , Navarro‐Santos Pedro , Beiza‐Granados Lidia , Rivera José L. , García‐Gutiérrez Hugo A. , Herrera‐Bucio Rafael 
Published: August 2019

AbstractThe regioselectivity of the conjugate addition between syringol (1) and the captodative olefin 3‐(p‐nitrobenzoyloxy)‐but‐3‐en‐2‐one (2) is evaluated under diverse solvent and Lewis acid catalyst conditions, providing a mixture of the para/meta phenol adducts. Experimental results revealed for most of the trials that the para regioisomer is the major one. However, there is not a clear correlation between the regioselectivity of products and the polarity of the tested solvents. In this work, the reactivity descriptors and the reaction mechanism are studied in the framework of the density functional theory (DFT) to give insights about the reactivity and regioselectivity of this reaction. The Parr functions difference is used as the reactivity descriptor in each stage of the reaction explaining quite well the involved transition states. Overall, it is found that the reactivity of 1 is strongly influenced by the presence of the catalyst, while the regioselectivity of the products depends on both the catalyst and the polarity of the solvent, finding that, the meta adduct is highly dependent of the presence of nonpolar solvents.
Cognitive and motor effects of Kinect‐based games training in people with and without Parkinson disease: A preliminary study
Authors: de Melo Cerqueira Thília Maria , de Moura Júlia Araújo , de Lira Juliana Onofre , Leal Josevan Cerqueira , D'Amelio Marco , do Santos Mendes Felipe Augusto 
Published: August 2019

AbstractObjectivePurpose of this study is to evaluate the effects of training with six commercial Xbox KinectTM games on cognitive and motor aspects in Parkinson's disease (PD) patients and to compare the effects with a group of paired healthy subjects.MethodsThis study was a quasi‐experimental, controlled trial. Eight individuals with PD (mean age 68.9 ± 7.9) and eight older adults without PD, matched by age (mean age 67.6 ± 7.3) were enrolled in the study. Ten sessions of six Xbox 360 KinectTM commercial games were performed for 5 weeks. Subjects were evaluated before and 7 and 30 days after intervention. They were assessed using Montreal Cognitive Assessment, Frontal Assessment Battery (FAB), Timed Up and Go test, Ten Meters Walking test, and Balance Berg Scale. The Freezing of Gait Questionnaire, the Movement Disorder Society Unified Parkinson Disease Rating Scale, and the Parkinson's disease Questionnaire were also applied to PD group.ResultsSignificant improvement was found for cognitive aspects measured by Montreal Cognitive Assessment and FAB in both groups but without retention on FAB in PD group. No significant improvements were found for motor aspects in none group.ConclusionMotor–cognitive training using Xbox KinectTM games is a feasible resource to improve executive functions in PD patients and in older healthy people.
Graphene Quantum Dot Embedded Hydrogel for Dissolved Iron Sensing
Authors: Pincher Daniel W. M. , Bader Christie A. , Hayball John D. , Plush Sally E. , Sweetman Martin J. 
Published: August 2019

AbstractA robust and accurate chemical sensor for dissolved iron has been developed, based on highly fluorescent graphene quantum dots (GQDs). This work describes the construction of a GQD embedded hydrogel that displays strong fluorescence emission from the bulk structure. The hydrogel is made from poly(2‐hydroxyethyl methacrylate) (pHEMA) and crosslinked by ethylene glycol dimethacrylate to form a water permeable, flexible and transparent material. Polymerisation in the presence of the GQDs physically entraps the fluorescent nanoparticles within the hydrogel. The fluorescence properties of the GQD‐pHEMA hydrogels have been thoroughly characterised, including by confocal microscopy in the first reported use of this technique for a GQD composite material. Sensing of dissolved Fe(III) by the GQD‐pHEMA hydrogels has been demonstrated, whereby the Fe(III) quenches the GQDs fluorescence emission. The GQD‐pHEMA hydrogels were selective to Fe(III) and showed a linear response for concentrations in the range of 10–200 μM.
Membrane‐Solvothermal Synthesis of Cobalt Ferrite/Reduced Graphene Oxide Nanocomposites and Their Photocatalytic and Electromagnetic Wave Absorption Properties
Authors: Guan Xiao‐Hui , Kuang Jia‐Min , Yang Liu , Lu Min , Wang Guang‐Sheng 
Published: August 2019

AbstractCobalt ferrite (CoFe2O4) nanorods have been synthesized by a membrane‐solvothermal method and a series of CoFe2O4/rGO nanocomposites with different reduced graphene oxide (rGO) weight ratios of 5%, 10%, 15%, 20%, 25% and 30% have been synthesized via ultrasonic treatment, named as CoFe2O4/rGO‐1, CoFe2O4/rGO‐2, CoFe2O4/rGO‐3, CoFe2O4/rGO‐4, CoFe2O4/rGO‐5 and CoFe2O4/rGO‐6, respectively. The photocatalytic activity was studied by photodegradation of malachite green (MG), and the wave absorbing performance was studied by network vector analyzer. CoFe2O4 had the function of magnetic separation, which had largely reduced the separation difficulty of photocatalyst and dye wastewater. Among all the graphene‐based composites, CoFe2O4/rGO‐5 has the most excellent photocatalytic performance which could eliminate about 93.48% of MG in 90 min. Even after five cycles, the photocatalytic degradation rate of MG was still above 88%, suggesting that CoFe2O4/rGO‐5 is a promising photocatalyst for recyclable utilization. The wave absorption test results showed that the electromagnetic wave reflection loss of CoFe2O4/rGO nanocomposites was lower than that of pure CoFe2O4, which showed that the addition of graphene could effectively enhance the absorbing properties of materials. When the thickness of the absorbing layer was 2.5 mm, the reflection loss of the CoFe2O4/rGO‐4 nanocomposite reached the maximum value of 17 GHz at ‐11.1 dB and the bandwidth of less than ‐10 dB was 2.3 GHz.
Selective and Solvent‐Free Synthesis of Isoxazole‐Containing Spiro‐Thiazolidinones Using TiO2‐SO3H as Solid Catalyst
Authors: Singh Ruby , Singh Aakash , Bhardwaj Diksha 
Published: August 2019

AbstractA solvent‐free nano‐titania‐supported sulfonic acid [nano‐TiO2‐SO3H (n‐TSA)] catalyzed approach has been developed for the synthesis of pharmaceutically interesting new hybrids of isoxazolyl‐spiro‐thiazolidinones. The key feature of present investigated three component reaction of cyclic ketones (isatin, ninhydrin and acenaphthenequinone), 3‐amino‐5‐methyl‐isoxazole and α‐mercaptocarboxylic acids involves the synthesis of a five member ring system instead of the anticipated seven member ring system & also exploits the possibility of other likely isomers, regio and diastereoselectively. The selectivity of synthesized spiro‐thiazolidinone systems was established, based on the spectroscopic outcome and single crystal X‐ray analyses of representative compounds. Further, the use of a solid catalyst, n‐TSA under solvent‐free conditions was observed to be the best choice of reaction conditions, as it not only afforded the product in higher yields in less reaction time but in an environmentally friendly manner as well.
A Condensation of Biginelli Products with 1,3‐Benzenediols: a Facile Access to Diastereomerically Pure Hexahydro‐5H‐chromeno[4,3‐d]pyrimidin‐5‐ones
Authors: Filimonov Sergey I. , Chirkova Zhanna V. , Kabanova Mariya V. , Makarova Elena S. , Shetnev Anton A. , Panova Valeria A. , Suponitsky Kyrill Yu. 
Published: August 2019

AbstractA new simple method for the synthesis of 2‐thioxo‐1,2,3,4,4a,10b‐hexahydro‐5H‐chromeno[4,3‐d]pyrimidin‐5‐ones via acid‐catalyzed condensation of Biginelli products with 1,3‐benzenediols was developed. The diastereoselectivity of this reaction was studied in details. A convenient work‐up procedure providing the major (4R*,4aS*,10bR*) diastereomer from the reaction mixture was found.
A ligand and Palladium‐free Avenue for Cyanation of Aryl Halides: The Art of Samarium Powder in C–C Coupling Reaction
Authors: Moghaddam Firouz Matloubi , Pourkaveh Raheleh , Gholamtajari Milad , Karimi Ashkan 
Published: August 2019

AbstractThis is the first study of samarium powder catalyzed cyanation reaction of aryl halides, bearing electron‐withdrawing and electron‐releasing substituents, in the presence of NaCN to afford corresponding benzonitriles in high yields. This protocol takes the advantage of being done in the absence of additive, ligand and precious transition metals such as palladium.
Activation Pathway of C‐H and C–C Bonds of Ethane by Pd Atom with CO2 as a Soft Oxidant
Authors: Yang Zhongqing , Lan Yan , Yan Yunfei , Guo Mingnv , Zhang Li 
Published: August 2019

AbstractEthane and CO2 can be converted to synthesis (CO and H2) via the dry reforming pathway and formed important industrial raw material ethylene through oxidative dehydrogenation pathway, which are relating to the C−C bond and C−H bond cleavage, respectively. In this study, density functional theory was used to study the activation reaction of ethane C−H bond, C−C bond on Pd atom with CO2 as oxidant. CH3CH3→CH2CH3+H→CH2CH2+2H is the dominant path for dehydrogenation to ethylene. Adding an appropriate amount of H2 can reduce the deep dehydrogenation of ethylene and increase the selectivity. Under the condition of 873 K with Pd atom as catalyst, it is more inclined to ethane/CO2 reforming reaction. The main route for generating CO is CH3CH2+H→CH3+CH3→CH2→CHOH→CHO→CO. H atoms are conducive to the activation of CO2, CO2+H→COOH→CO+OH is the dominant reaction pathway for CO2 activation. The first reaction in the whole system is the first C−H bond cleavage of ethane.
7‐Oxy‐3,4‐cyclohexenecoumarin Carrying Novel Zinc(II) and Indium(III) Acetate Phthalocyanines: Synthesis, Characterization, Photophysical and Photochemical Properties
Authors: Karapınar Begümhan , Özdemir Mücahit , Salan Ümit , Durmuş Mahmut , Yalçın Bahattin , Bulut Mustafa 
Published: August 2019

AbstractIn this study, 7‐hydroxy‐3,4‐cyclohexenecoumarin (1), two new phthalonitriles, 7‐(2,3‐dicyanophenoxy)‐3,4‐cyclohexene‐coumarin (2), 7‐(3,4‐dicyanophenoxy)‐3,4‐cyclohexenecoumarin (3), were prepared. The phthalonitrile derivatives 2 and 3 were converted to the respective non‐peripheral tetra, peripheral tetra 7‐oxy‐3,4‐cyclohexenecoumarin substituted zinc(II) (4,6) and indium(III)acetate phthalocyanine (5,7) derivatives. All novel purified compounds (2‐7) were characterized by elemental analysis, FT‐IR, UV‐vis, 1H NMR, 13C NMR, MALDI‐TOF mass data. The spectral, photophysical (fluorescence quantum yields and lifetimes), and photochemical (singlet oxygen generation and photodegradation under light irradiation) properties of the synthesized Pcs (4‐7) were studied in DMF, and the results were compared to determine the effects of the locations of substituents and the diversity of the central metal atom on these properties. The 7‐oxy‐3,4‐cyclohexenecoumarin bearing phthalocyaninatozinc(II) and indium(III)acetate complexes showed good solubility in organic solvents such as chloroform, dichloromethane, tetrahydrofuran, acetone, DMF and DMSO. The fluorescence quenching behavior were investigated using 1,4‐benzoquinone as a quencher. They have an acceptable level of singlet oxygen production, which determines the usability of phthalocyanines in photodynamic therapy applications and demonstrated appropriate photodegradation. The thermal properties of Pcs (4‐7) were also investigated.