bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validated Chromatographic Methods for Simultaneous Estimation of Cinnarizine in Binary Mixture with Domperidone and Paracetamol in Tablets
Authors: Mahrouse Marianne Alphonse , El-Zaher Asmaa Ahmed , Al-Ghani Ahmed Mohammed 
Published: March 2018

Background:Cinnarizine, an antihistaminic drug, is commonly formulated in combination with domperidone and with paracetamol for treatment and prevention of motion sickness and migraine.Objective:The aim of this work was to develop new, simple, precise and selective chromatographic methods (RP-HPLC and TLC-densitometric methods) for the determination of these drugs. These methods can be used as analytical tools in the routine examination in quality control laboratories.Methods:The first method was RP-HPLC method, the separation was carried out on an Inertsil® ODS- 3V C18 column (250 mm × 4.6 mm, 5 µm) using a mobile phase composed of methanol: acetonitrile (45: 55, v/v) at a flow rate of 1 ml/min. The detection was carried out at 220 nm. The second method was a TLC-densitometric method where the studied components were separated using a developing system composed of toluene: ethyl acetate: methanol: triethylamine (5: 4.3: 0.7: 0.5, v/v/v/v) on TLC silica gel 60 F254 plates, followed by densitometric scanning at 270 nm.Results:In RP-HPLC method, the peaks were sharp and well separated, the retention times were 5.25, 3.48 and 2.78 min, for cinnarizine, domperidone and paracetamol, respectively. Linearity was obtained over the concentration ranges 1-22, 0.75-16.5 and 25-550 µg/ml, for cinnarizine, domperidone and paracetamol, respectively. In TLC-densitometric method, good separation of spots and linear relationships were achieved over the concentration ranges of 0.2-2, 0.15-1.5 and 5-50 µg/spot, for cinnarizine, domperidone and paracetamol, respectively. Method validation was conducted according to ICH guidelines in terms of linearity, accuracy, selectivity, precision and robustness.Conclusion:The developed methods were applied for the determination of the cited drugs in tablets containing binary drug mixtures. The methods are simple and precise and can be used for routine analysis of the labelled drugs in combined dosage forms in quality control laboratories.
Crystallographic Features and Nature of Luminescence Centres of the Niobate and Tantalate Compounds with Layered Perovskite-Like Structure
Authors: Chukova Oksana , Nedilko Sergiy , Titov Yuriy , Sheludko Vadym 
Published: March 2018

Aim and Objectives
The ultrafine powders of the perovskite-like layered AII3LaM3O12 (AII = Sr, Ba; M = Nb, Ta) compounds have been synthesized by heat treatment of co-precipitated hydroxy-carbonates. The luminescence of these compounds is reported for the first time.

Methods:
Luminescence spectra of all studied compounds are complex and contain two main wide bands with maxima near 2.9 and 2.5 eV. These luminescence bands were assigned to radiation electron transitions in the MoO67- molecular groups of different symmetry located in the various lattice positions.

Conclusion:
The energy levels scheme of the MoO67- group and related radiation and absorption transitions had been proposed.
Taxonomic description and annotation of Poa albertii Regel (Poaceae: Pooideae, Poeae, Poinae) from North Western Himalayas, India.
Authors: Bhat Mudassir Ahmad , Shakoor Sheikh Abdul , Soodan Amarjit Singh 
Published: March 2018

Poa albertii Regel, a native to Central Asia, has been described from North-Western Himalayan region and annotated to the latest system of grass classification. A detailed taxonomic description in the latest format, along with illustrations and Scanning Electron Micrograph of diagnostic features is provided to diagnose P. albertii Regel from allied species.
Proteomic study of salt tolerant cyanobacterium Anabaena sp. BHUAR002 isolated from Usar soil
Authors: Rai Aparna 
Published: March 2018

Salt stress leads to an alteration in protein profile and induction of stress-specific proteins. The SDS – PAGE analysis of total soluble proteins of Anabaena sp. BHUAR002 (Accession no. bankit1353506 HM235817) exposed to 500 mM NaCl for 24 h revealed inhibition of host proteins, induction of selected proteins and appearance of some new proteins. In view of the appreciable alteration in total soluble protein profile after 500 mM salt treatment for 24 h, this dose was selected for further physiological, biochemical and proteomic analysis of the response of Anabaena sp. BHUAR002 to salinity and to examine the relationship between these responses. Further, 2DE of the total soluble protein of Anabaena sp. BHUAR002 showed 73 spots present only in control, 43 spots present only in stress and 15 differentially expressed spots present in both control and stress but show different levels of expression. This may be due to disturbance of cellular homeostasis by salt stress. Out of fifteen, Six spots were identified after MALDI-TOF MS analysis were identified as Manganese and iron Superoxide dismutase [Anabaenavariabilis ATCC 29413], Cytidine deaminase [Porphyromonas venonis 60-3], Phycobilisome Protein [Nodularia Spumigena CCY9414], DNA replication and repair protein recF [Yersinia aldovae ATCC35236], IS1112 transposase [Xanthomonas oryzae pv.oryzae PXO99A] and TP901 family phage tail tape measure protein [Xanthobacter autotrophicus Py2].
Ethnomedicinal plants in Parammakonda, Konada, Nareduvalasa and Jayathi sacred groves in Vizianagaram, Andhra Pradesh, India
Authors: Katta Jhansi , S.M. Khasim , R.M. Venkatesh 
Published: March 2018

Sacred Groves are the places of Natural vegetation being protected by the people with a firm belief on Nature and God. The tradition of worshipping nature, trees is a practise all over the world. This made them rich with flora and biological wealth. The groves are beneficial to mankind as they had medicinal, economical, agricultural and edible plants. The present groves are Parammakonda, Jayathi, Nareduvalasa and Konada. Ethnobotanical uses of 103 species belonging to 95 genera and 53 families used by the tribal Kondadora, fishermen and other people are identified and the local name, scientific name, family, habit and uses are documented during the study. Maximum species belong to Euphorbiaceae (8) and Fabaceae (8). The tribal people are using more plant species for treating skin diseases. The leaf part is profusely used followed by stem, root and fruit, trees are used mostly for the herbal medicine. Many plant species which are endemic, endangered and rare are also preserved in the groves. They are the repositories of genetic diversity and play an impotant role in cleaning environment. They play multifunctional role in local communities, thus there is an urgent need to conserve them and to protect the biodiversity.
Micro-morphological descriptions on Cenchrus species from Rajasthan (India)
Authors: Arora Sunita , Kumar Ganesh 
Published: March 2018

Present investigation was carried out to screen micro-morphological features of Cenchrus species (C4 plant) belonging to family Poaceae. This is an important medicinal, fodder as well as crop plant and traditionally used as famine food during drought. It is best suited for desert environmental conditions. In extreme conditions when food is in scarce, seeds of this grass are consumed by tribals. The microscopical illustrations revealed several interesting features i.e. presence of cuticle, bulliform cells, trichomes, lysigenous cavity, more amount of chlorenchyma, Y- shaped vascular bundles, double layered bundle sheath, large vessels and starch grains that support its assimilation efficacy and survival in typical conditions of Thar Desert. This study helps in referential identification, authentication, standardization and detection of adaptation strategies to understand biology of this plant.
De la moneda metálica al billete de banco en Medellín y Bogotá (1871-1885): complementariedad y sustitución de medios de pago en un régimen de banca libre
Authors: Acuña Mantilla Kelly Vanessa , Álvarez Andrés 
Published: March 2018

El estudio de la circulación monetaria durante la llamada era de “banca libre” en Colombia (1865-1885) muestra patrones diferentes según las regiones. Este trabajo estudia la complementariedad y sustitución entre la moneda metálica acuñada legalmente y los billetes de bancos privados. Se pone en evidencia la existencia de mecanismos de sustitución entre monedas de oro y billetes bancarios para el caso de Antioquia, mientras que en el caso de Bogotá no se puede afirmar que la evidencia sea concluyente. El patrón de comportamiento de la acuñación de monedas de plata, por el contrario, muestra complementariedad con el billete de banco en ambas regiones. Este trabajo concluye que en Colombia se presentó una forma de Ley de Gresham particular. Se muestra evidencia que permitiría concluir que las diferenciasregionales en el funcionamiento de este mecanismo se deben a la especialización de la región de Medellín (estado de Antioquia) como mayor productor y exportador de oro, de donde se puede inferir un mayor costo de oportunidad de la circulación de este metal y una tendencia a adoptar más fácilmente formas de moneda fiduciaria. Esto no es completamente cierto para Bogotá, cuya economía se especializa en agricultura, servicios comerciales y artesanado.
Los sectores agroindustriales de Argentina y Brasil, 1990-2010, y su evolución comparada
Authors: Muro de Nadal Mercedes , Merlo Susana 
Published: March 2018

Las economías de Argentina y Brasil marcaron una fuerte impronta productiva y exportadora agroindustrial en las dos últimas décadas. Ambos fueron socios iniciales y promotores de la integración regional en el Mercosur, pero presentaron a lo largo del período una evolución dispar. Los principales factores que marcaron esas diferencias debemos buscarlos en el comportamiento de los mercados internacionales, las innovaciones tecnológicas, el clima, los capitales invertidos y, en especial, la incidencia de las políticas internas de cada país. Una desproporción en el tamaño de sus mercados internos, crisis internacionales, crisis dentro delos países, devaluaciones, relaciones con otros bloques y políticas de diferente signo, fueron algunos de los desafíos por los que transitaron ambos.El objetivo de este trabajo es analizar entonces la evolución del sector de la producción agroindustrial en ambos países por medio del análisis comparativo y plantear el debate académico necesario para identificar las causas de las evoluciones dispares; así mismo, sugerir cuáles son las herramientas más útiles para el desarrollo a largo plazo de Argentina o de otros países enfrentados a disyuntivas similares.
Pueblo, revolución y violencia. Las reactualizaciones revolucionarias del populismo
Authors: Slipak Daniela , Giménez Sebastián R 
Published: March 2018

<p>En el presente trabajo se propone analizar los procesos de resignificación identitaria llevados a cabo por agrupaciones que asociaron la reivindicación de los populismos a consignas “revolucionarias” y que consideraron el uso de la violencia como un modo legítimo de intervenir en la escena pública. Para ello, se estudiaron los casos de Fuerza de Orientación Radical de la Joven Argentina (forja) y Montoneros, los cuales tuvieron lugar en distintos momentos de la historia argentina. El análisis de ambas experiencias desde una perspectiva comparada permite vislumbrar cómo los rasgos específicos de la matriz populista, sus oscilaciones y tensiones, tienden a rigidizarse en las reapropiaciones “revolucionarias” de su tradición</p>
Home Dental Bleaching Monitored With Microelectronic Sensors to Record the Wearing Times of an Acetate Tray/Bleaching Product
Authors: Pavani CC , Sundfeld D , Schott TC , Bertoz APM , Bigliazzi R , Sundfeld RH 
Published: March 2018

SUMMARY
The present case study quantifies the clinical wearing time of an acetate tray/bleaching product during home dental bleaching. The patient was instructed to use a 10% carbamide peroxide gel for 6-8 hours each day for 20 days. The wearing time of the tray was measured by a microsensor from TheraMon microelectronic system (Sales Agency Gschladt, Hargelsberg, Austria) completely embedded in the tray so that the clinician would be informed as to the precise time the tray was placed in the mouth. Evaluation of the daily printout during dental bleaching demonstrated that the patient did not correctly follow the clinician's instructions as to the wearing time of the tray. Recording the wearing time of dental bleaching agents can be beneficial for both dental professional and patient to obtain a more effective treatment according to the patient's needs and expectations.
The effectiveness of telemedicine on stigmatization and treatment burden in patients with health compromising lifestyles and chronic diseases: A critically appraised topic
Authors: Obisike Ebere Ellison 
Published: March 2018

Objectives: To conduct a critical appraisal of peer reviewed articles on the effectiveness of telemedicine on stigmatization and treatment burden in patients with health compromising lifestyles and chronic diseases.Methods: This study critically appraised peer-reviewed article on the effectiveness of telemedicine on stigmatization and treatment burden in patients with health compromising lifestyles and chronic diseases. Treatments included e-health interventions, information and communication technologies used in health care, internet-based interventions for diagnosis and treatments that encouraged collaborative care for patients with chronic diseases. This paper critically appraised the full text of each relevant peer-reviewed article adapting the Occupational Therapy Critically Appraised Topics (CATs) template while using the Oxford Centre for Evidence-based Medicine- Levels of Evidence (2011) model to assess for best evidence or quality. Results: Initial internet search using Psychinformation; PubMed; Medline; ProQuest; CINAHL; OT seeker and the Cochrane Library generated over 1450 titles/abstracts. Following abstract appraisal, 30 articles were selected for full text assessment. Five of the final articles selected for this critical appraisal alluded to the effectiveness of telemedicine in reducing the treatment burden of stigmatization on patients with chronic diseases. Majority of the appraised articles indicated the effectiveness of telemedicine in changing behaviours.Conclusions: All the appraised articles alluded to the effectiveness of telemedicine in curbing some of the treatment burdens of stigmatization for patients with health compromising lifestyles and chronic diseases. However, it is evident that the use of other intervention methods such as government policy, public education and patient empowerment in conjunction with telemedicine would better reduce the effect of stigmatization and facilitate the medical interventions for patients with chronic diseases.
Osteocalcin improved Spermatogenesis in Azoospermic Mouse Model
Authors: Rastegar Tayebeh , Shafaat Pedram , Noori Mougahi Seyed Mohammad Hosein , Parvari Soraya , Solhjo Somayeh , Tooli Heidar , Nejad Mahsa Yaahoobi , Dhulqarnain Akanji Omotosho 
Published: March 2018

Infertility is one of the major health concerns in the world whose globally incidence rate is on the rise. Several hormones are effective in this process, such as testosterone, estrogen and Osteocalcin (OCN). The Osteocalcin has Gprc6a receptors on leydig cells, which promotes the production of testosterone when mounted on these receptors. Therefore, the aim of this study was to investigate the role of Osteocalcin on the improvement of spermatogenesis and expression of Gprc6a receptors on leydig cells in the azoospermic mouse model.Twenty-five mice (4 to 6 weeks) were randomly divided into five groups: control, sham I Group that was initially injected by busulfan solvent (DMSO) at 5 weeks old and then by Osteocalcin solvent (PBS) after 5 weeks for one month, azoospermia Group that received busulfan (40 mg/kg/ip) at 5 weeks old. Sham II Group received busulfan 40mg/kg/ipandt hen after 5 weeks received PBS and experimental group, including azoospermic mice, was administered by Osteocalcin (3ng/g/d) for one month. After the last injection, the tests were dissected and then exposed to the tissue passage. To measure morphological changes, H & E staining was performed on a number of sections to measure the diameter of the seminiferous tubule, thickness of the germinal layer, count the spermatogonial cells, spermatocyte, round spermatid, long spermatid, Sertoli, leydigandmyoid cells. Image J software was used to conduct quantitative studies. Immunohistochemical method was employed to examine the expression of the specific receptor of Osteocalcin, Gprc6α, in the Leydig cell among the groups.The H & E staining showed a significant difference in the count the spermatogonial cells, spermatocytes, round spermatids, long spermatids, the thickness of the germ layer, the seminiferous tubule diameter between the studied groups (P<0.05).There was also no significant difference in the count of Sertoli, leydig, myoid cells and seminiferous tubule diameter between the groups (P<0.05). In the immune histochemistry, no significant difference was found in the count of GpRC6α-positive leydig cells between the groups (P< 0.05).According to the current results, the OCN plays an important role in spermatogenesis, which has a positive effect on the count of spermatocytes and spermatids, and can be further explored as an appropriate therapeutic strategy proposed for the infertility.
Persepsi Masyarakat terhadap Kurikulum Pendidikan Anak Usia Dini
Authors: -- Sutjipto 
Published: March 2018

The purpose of this study is to obtain public perceptions of early childhoodÂ education curriculum. The study used a case study approach with positivistic researchÂ paradigm and conducted from September to November 2014. Data analysis was performedÂ using simple descriptive analysis in the form of a narrative. The results shows that theÂ issue of curriculum and its implementation is not just the domain of curriculum developers,Â but also other aspects perceived as significant issues by the community. First, publicÂ perceives the importance of the rational of development, the cornerstone of development,Â strategy and procedure of development, structure and content of the curriculum,Â implementation strategies, and the existence of books and equipment in the context ofÂ curriculum design. Second, regarding the presence of the developed early childhood educationÂ curriculum, society strongly perceives that the document has been considering variousÂ aspects to the growing of interest for early childhood in practice of reading, writing, speaking,Â socializing/making friends, eating and drinking together, discipline, manners , faith, andÂ playing activities, singing, marching, and exercise. Third, the implementation of theÂ curriculum is perceived by society as an in need of harmonies cooperation among educationalÂ institutions, public, and educational supervisors in the region, especially in terms of teachingÂ staff, procurement of books and equipment and other support resources.ABSTRAKÂ Tujuan dari penelitian ini adalah memperoleh persepsi masyarakat terhadapÂ kurikulum pendidikan anak usia dini. Penelitian menggunakan pendekatan studi kasusÂ dengan paradigma penelitian positivistik, dan dilakukan pada bulan September sampaiÂ November 2014. Analisis data dilakukan dengan menggunakan analisis deskriptif sederhanaÂ dalam bentuk naratif. Hasil penelitian menunjukkan bahwa isu kurikulum dan penerapannyaÂ tidak hanya ranah pengembang kurikulum melainkan juga beberapa hal dipersepsikan secaraÂ cukup signifikan oleh masyarakat. Pertama, masyarakat mempersepsi penting terhadapÂ rasional pengembangan, landasan pengembangan, strategi dan prosedur pengembangan,Â struktur dan isi kurikulum, strategi implementasi, dan keberadaan buku dan peralatanÂ dalam konteks desain kurikulum. Kedua, berkaitan dengan kurikulum pendidikan anakÂ usia dini yang dikembangkan, masyarakat mempersepsi secara kuat bahwa dokumenÂ tersebut telah mempertimbangkan berbagai aspek kepentingan untuk tumbuh kembangnyaÂ anak usia dini dalam berlatih membaca, menulis, berbahasa, bersosialisasi/berteman, makanÂ dan minum bersama, berdisiplin, bertata krama, sopan santun, aqidah keimanan, kegiatanÂ bermain, bernyanyi, baris-berbaris, dan berolahraga. Ketiga, pengimplementasian kurikulumÂ dipersepsi oleh masyarakat sangat memerlukan kerja sama yang harmonis antara lembagaÂ pendidikan, masyarakat dan pembina pendidikan di daerah terutama dalam hal tenagaÂ pendidik, pengadaan buku dan peralatan serta sumber daya pendukung lainnya.
Kinerja Pendidikan Anak Usia Dini dan Pendidikan Nonformal Berdasarkan Misi Pendidikan
Authors: Dewi Hermawan Ida Kintamani 
Published: March 2018

The purpose of this writing is to study the potential of early childhood education (ECE) and nonformal education (NFE), educational indicators based on education mission,Â and performance of ECE and NFE. The method used is documentation or reference study.Â Analysis is held by descriptive method using educational indicators based on educationÂ mission, that is, availability, quality, equality, and assurance of service. The results showsÂ that the potential of seven programs (literacy, ECE, Packet A, Packet B, Packet C and courses)Â had accommodated 12.9 million students, 575.6 thousand facilitators, and 160.9 thousandsÂ organizers. Besides that, based on education mission with the ideal value of100, the valueÂ of availability was 84.48, quality was 59.92, equality was 83.85, and services assuranceÂ was 73.45 so that the performance became 75.43. To conclude, both ECE and NFE has theÂ lowest performance from its quality and the highest performance from its availability.ABSTRAKÂ Tujuan penulisan ini adalah untuk mengkaji potensi layanan pendidikan anakÂ usia dini (PAUD) dan pendidikan nonformal (PNF), indikator pendidikan berdasarkan misiÂ pendidikan, dan kinerja PAUD dan PNF tahun 2012. Metode yang digunakan adalah studiÂ dokumentasi atau kepustakaan. Analisis dilakukan secara deskriptif menggunakan indikatorÂ pendidikan berdasarkan misi pendidikan, yaitu ketersediaan, kualitas, kesetaraan, kepastianÂ layanan. Hasil kajian menunjukkan bahwa potensi 7 layanan pendidikan (pendidikanÂ keaksaraan (PK), PAUD, TK, Paket A, Paket B, Paket C, dan kursus) telah berhasilÂ menampung 12,9 juta peserta didik, dengan pendidik sebesar 575,6 ribu, dan pengelolaÂ sebesar 160,9 ribu. Selain itu, berdasarkan misi pendidikan dengan nilai ideal 100 makaÂ ketersediaan sebesar 84,48, kualitas sebesar 59,92, kesetaraan sebesar 83,85, danÂ kepastian sebesar 73,45 sehingga kinerjanya menjadi 75,43. Simpulannya, kinerja PAUDÂ dan PNF yang terendah adalah pada kualitas layanan dan yang tertinggi adalah padaÂ ketersediaan layanan.