bluuebunny/crossref_metadata_2025_split huggingface dataset:
Redefining writing in the foreign language curriculum: Toward a design approach
Authors: Allen Heather Willis 
Published: August 2018

AbstractNumerous scholars have critiqued a lack of focus on foreign language (FL) writing in the second language (L2) acquisition research base and in FL programs in the United States. This position article argues for reimagining the role of writing to maximize learners’ 21st‐century skill development and FL programs’ contributions to broader institutional missions. After discussing selected research on L2 writing and its uptake in FL curricula, an integrated pedagogy is proposed—a design approach—that incorporates insights from New Literacy Studies and L2 writing research and posits writing as a purposeful, collaborative act of communication that entails both learner agency and attention to textual conventions. Key foci of this approach are highlighted, and a description is provided of how a design approach relates to challenges in FL writing instruction. Finally, next steps in researching and implementing this approach are offered.
Application of smart bracelet to monitor frailty‐related gait parameters of older Chinese adults: A preliminary study
Authors: Zhong Runting , Rau Pei‐Luen Patrick , Yan Xinghui 
Published: August 2018

AimSmart bracelets are popular today. Based on their built‐in motion sensors, they can serve as a cost‐effective method of gait assessment in home‐based care. Few studies have applied smart bracelets in the gait assessment of older Chinese adults. The present study aimed to: (i) establish reference gait parameters of older Chinese adults using smart bracelets under single and dual task; and (ii) explore the differences in gait parameters among non‐frail and pre‐frail Chinese older adults.MethodsA total of 50 community‐dwelling older Chinese adults aged ≥50 years wore a smart bracelet sensor in the L3 region of the back and underwent a 10‐m walking test under single‐ and dual‐task conditions. Participants were preliminarily classified into non‐frail and pre‐frail groups based on the Fatigue, Resistance, Ambulation, Illnesses and Loss of Weight scale. Gait parameters including average walking speed, step frequency, root mean square (RMS), acceleration amplitude variability, step variability, step regularity and step symmetry were calculated based on the data exported from the bracelet.ResultsMultivariate analysis of covariance (mancova) analysis showed that older adults had significantly decreased speed and step frequency (P < 0.05) under the dual cognitive task condition. Pre‐frail older adults showed significantly decreased speed, mediolateral RMS, vertical RMS, anteroposterior RMS, vertical amplitude variability and vertical step regularity compared with non‐frail older adults (P < 0.05).ConclusionsThe present study suggested that the decline in gait parameters as a result of frailty could be detected by the smart bracelet sensor. Geriatr Gerontol Int 2018; 18: 1366–1371.
Automated Time Series Modeling for Piezometers in the National Database of the Netherlands
Authors: Zaadnoordijk Willem J. , Bus Stefanie A.R. , Lourens Aris , Berendrecht Wilbert L. 
Published: August 2018

AbstractThe Geological Survey of the Netherlands (TNO‐GSN) maintains a public national database of groundwater head observations. Transfer function‐noise modeling has been applied to the time series in order to extract the impulse response functions for precipitation and evaporation for each piezometer. An automated procedure has been developed to assess the quality of the time series and of the models. The time series models of sufficient quality offer far more homogeneous data on the piezometric head than the original measurements. This allows for improved mapping of the head at a specific date or of characteristics of the head like average summer or winter levels. Also, the separation of precipitation and evaporation from other influences is useful for groundwater management and policy. The individual time series models are available online with interactive graphics (https://www.grondwatertools.nl/grondwatertools‐viewer). The spatial patterns of the impulse response function characteristics can support analyses of the groundwater system.
Economic, institutional, and socio‐cultural determinants of consumer credit in the context of monetary integration
Authors: Borowski Jakub , Jaworski Krystian , Olipra Jakub 
Published: August 2018

AbstractWe investigated the determinants of consumer credit in relation to nominal GDP in 23 EU countries using panel regressions for 1997–2014. Our contribution to existing research is evidence that both higher density of bank units and greater concentration of the banking sector lead to higher consumer lending. Our results show that the consumer credit to GDP ratio decreases when banking supervision becomes a part of a politically independent central bank. This signals that access to consumer credit is more difficult when supervision is independent from government. Finally, we find that joining the Eurozone boosts consumer lending. This result is consistent with the permanent income hypothesis, which states that households’ current consumption is determined not only by their current income but also by the income that they expect to earn. Our results can be used to increase the effectiveness of macroprudential policy in avoiding consumer lending booms and ensuring financial stability.
Observations on research with spores of Bacillales and Clostridiales species
Authors: Setlow Peter 
Published: August 2018

Summary
The purpose of this article is to highlight some areas of research with spores of bacteria of Firmicute species in which the methodology too commonly used is not optimal and generates misleading results. As a consequence, conclusions drawn from data obtained are often flawed or not appropriate. Topics covered in the article include the following: (i) the importance of using well-purified bacterial spores in studies on spore resistance, composition, killing, disinfection and germination; (ii) methods for obtaining good purification of spores of various species; (iii) appropriate experimental approaches to determine mechanisms of spore resistance and spore killing by a variety of agents, as well as known mechanisms of spore resistance and killing; (iv) common errors made in drawing conclusions about spore killing by various agents, including failure to neutralize chemical agents before plating for viable spore enumeration, and equating correlations between changes in spore properties accompanying spore killing with causation. It is hoped that a consideration of these topics will improve the quality of spore research going forward.
Cessation of pacing in super‐responders of cardiac resynchronization therapy: A randomized controlled trial
Authors: Liang Yixiu , Wang Qingqing , Zhang Mingliang , Wang Jingfeng , Chen Haiyan , Yu Ziqing , Gong Xue , Su Yangang , Ge Junbo 
Published: August 2018

AbstractBackgroundThe consequence of cessation of biventricular pacing in super‐responders of cardiac resynchronization therapy (CRT) has not been fully investigated.MethodsIn this prospective, single‐blinded clinical trial, 21 super‐responders were randomly assigned to the ceased pacing (CeP, 11 patients) group or the continued pacing (CoP, 10 patients) group. Patients randomized to the CeP group underwent cessation of biventricular pacing. New York Heart Association (NYHA) class, quality of life (QOL) assessed with Minnesota questionnaire, 6‐minute walking distance (6MWD), left ventricular end systolic volume (LVESV), left ventricular end‐diastolic volume (LVEDV), and left ventricular ejection fraction (LVEF) were compared between groups at 3‐ and 6‐month follow‐up.ResultsNo significant difference was observed between the CeP and CoP groups regarding NYHA class, QOL, 6MWD, LVESV, LVEDV, or LVEF after 3 months (all P > 0.05). After 6 months, there existed no significant difference between the CeP and CoP groups with regard to NYHA class, QOL, 6MWD, LVESV, and LVEDV (all P > 0.05); however, LVEF was significantly lower in the CeP group than that of the CoP group (0.49 ± 0.10 vs 0.60 ± 0.11, P = 0.04), and LVEF was significantly reduced in the CeP group compared with the baseline value at randomization (0.49 ± 0.10 vs 0.54 ± 0.06, P = 0.04).ConclusionLVEF was significantly reduced in super‐responders of CRT 6 months after cessation of pacing. Super‐responders to CRT should receive continued, long‐term pacing to preserve recovered LV function.
Limited performance of MALDI‐TOF for identification of fish Aeromonas isolates at species level
Authors: Pérez‐Sancho M , Cerdá I , Fernández‐Bravo A , Domínguez L , Figueras M J , Fernández‐Garayzábal J F , Vela A I 
Published: August 2018

AbstractThe aim of this study was to evaluate the usefulness of the MALDI‐TOF MS to identify 151 isolates of Aeromonas obtained mostly from diseased fish. MALDI‐TOF MS correctly identified all isolates to the genus level but important differences in the percentage of isolates correctly identified depending on the species were observed. Considering exclusively the first identification option, Aeromonas bestiarum, Aeromonas hydrophila, Aeromonas salmonicida, Aeromonas veronii and Aeromonas sobria were the best identified with results >95%. However, considering the first and second identification options, the only species that showed values >90% was A. hydrophila. Overall, when the database was supplemented with 14 new spectra, the number of accurate identifications increased (41% vs. 55%) and the number of inconclusive identifications decreased (45% vs. 29%), but great differences in the success of species‐level identifications were found. Species‐distinctive mass peaks were identified only for A. hydrophila and A. bestiarum (5003 and 7360 m/z in 95.5% and 94.1% of their isolates, respectively). This work demonstrates the utility of MALDI‐TOF MS for Aeromonas identification to the genus level, but there is no consistency for the accurate identification of some of the most prevalent species implicated in fish disease.
Fracture resistance and survival of implant‐supported, zirconia‐based hybrid‐abutment crowns: Influence of aging and crown structure
Authors: Elshiyab Shareen H. , Nawafleh Noor , Walsh Laurence , George Roy 
Published: August 2018

AbstractAimThe aim of the present study was to investigate fracture resistance of implant‐supported zirconia‐based crowns (monolayer vs bilayer) cemented to hybrid abutments.MethodsMonolayer and bilayer zirconia crowns were constructed and cemented to zirconia hybrid abutments. Crowns were divided into two subgroups: (a) untreated control group; and (b) experimental group, which underwent thermal‐cycling mechanical loading in a chewing simulator. Up to 1.2 million stress cycles with simultaneous thermocycling (5 and 55°C) were applied. Samples were finally subjected to static load to fracture. Data were analyzed using one‐way analysis of variance and t test. Fractured surfaces were observed using scanning electron microscopy.ResultsMonolayer zirconia crowns had a 100% survival rate upon completion of the thermal mechanical loading, whereas bilayer zirconia crowns had a 50% survival rate. The fracture load of monolayer zirconia crowns was significantly higher than that of bilayer crowns. Moreover, the fracture load was significantly reduced in monolayer zirconia crowns after aging. Monolayer zirconia crowns showed bulk fracture within the monolayer, while bilayer crowns exhibited cohesive fracture within the veneering porcelain only.ConclusionsMonolayer implant‐supported hybrid‐abutment crowns exhibit significantly higher fracture resistance compared to bilayer crowns, making them better suited to handle higher masticatory loads encountered in the posterior region of the mouth.
Controlled attenuation parameter does not predict hepatic decompensation in patients with advanced chronic liver disease
Authors: Scheiner Bernhard , Steininger Lisa , Semmler Georg , Unger Lukas W. , Schwabl Philipp , Bucsics Theresa , Paternostro Rafael , Ferlitsch Arnulf , Trauner Michael , Reiberger Thomas , Mandorfer Mattias 
Published: August 2018

AbstractBackground & AimsAssessment of hepatic steatosis by transient elastography (TE)‐based controlled attenuation parameter (CAP) might predict hepatic decompensation. Therefore, we aimed to evaluate the prognostic value of CAP in patients with compensated advanced chronic liver disease (cACLD) and decompensated cirrhosis (DC).MethodsA total of 430 patients who underwent TE (liver stiffness ≥10 kPa) and CAP measurements were included in this retrospective analysis. Half of patients (n = 189) underwent simultaneous HVPG measurement. In cACLD patients, first hepatic decompensation was defined by new onset of ascites, hepatic encephalopathy or variceal bleeding. In patients with DC, the following events were considered as further hepatic decompensation: requirement of paracentesis, admission for/development of grade 3/4 hepatic encephalopathy, variceal (re‐)bleeding or liver‐related death.ResultsFirst hepatic decompensation occurred in 25 of 292 (9%) cACLD patients, while 46 of 138 (33%) DC patients developed further hepatic decompensation during a median follow‐up of 22 and 12 months respectively. CAP was not predictive of first (cACLD; per 10 dB/m; hazard ratio [HR]: 0.97, 95% confidence interval [95% CI]: 0.91‐1.03, P = 0.321) or further hepatic decompensation (DC; HR: 0.99, 95% CI: 0.94‐1.03, P = 0.554) in adjusted analysis. Using the well‐established CAP cut‐off of ≥248 dB/m for hepatic steatosis, the incidence of first (cACLD; P = 0.065) and further hepatic decompensation (DC; P = 0.578) was similar in patients with hepatic steatosis or without. Serum albumin levels (per mg/dL; HR: 0.83, 95% CI: 0.77‐0.89, P < 0.001) and MELD‐Na (per point; HR: 1.15, 95% CI: 1.04‐1.28, P = 0.006) in cACLD and MELD‐Na (per point; HR: 1.12, 95% CI: 1.05‐1.19, P < 0.0001) in DC patients were the only parameters independently associated with first and further hepatic decompensation, respectively.ConclusionControlled attenuation parameter does not predict the development of first (cACLD)/further (DC) hepatic decompensation, while serum albumin levels and MELD‐Na are of prognostic value.
Estimated burden of serious human fungal diseases in Turkey
Authors: Hilmioğlu‐Polat Süleyha , Seyedmousavi Seyedmojtaba , Ilkit Macit , Hedayati Mohammad Taghi , Inci Ramazan , Tumbay Emel , Denning David W. 
Published: August 2018

SummaryThe current number of fungal infections occurring each year in Turkey is unknown. We estimated the burden of serious human fungal diseases based on the population at risk, existing epidemiological data from 1920 to 2017 and modelling previously described by the LIFE program (http://www.LIFE-worldwide.org). Among the population of Turkey (80.8 million in 2017), approximately 1 785 811 (2.21%) people are estimated to suffer from a serious fungal infection each year. The model used predicts high prevalences of allergic fungal rhinosinusitis episodes (312 994 cases) (392/100 000), of severe asthma with fungal sensitisation (42 989 cases) (53.20 cases/100 000 adults per year), of allergic bronchopulmonary aspergillosis (32 594 cases) (40.33/100 000), of fungal keratitis (26 671 cases) (33/100 000) and of chronic pulmonary aspergillosis (5890 cases) (7.29/100 000). The estimated annual incidence for invasive aspergillosis is lower (3911 cases) (4.84/100 000 annually). Among about 22.5 million women aged 15‐50 years, recurrent vulvovaginal candidiasis is estimated to occur in 1 350 371 (3342/100 000) females. The burden of three superficial fungal infections was also estimated: tinea pedis (1.79 million), tinea capitis (43 900) and onychomycosis (1.73 million). Given that the modelling estimates reported in the current study might be substantially under‐ or overestimated, formal epidemiological and comprehensive surveillance studies are required to validate or modify these estimates.
On the mechanisms of development in monocot and eudicot leaves
Authors: Conklin Phillip A. , Strable Josh , Li Shujie , Scanlon Michael J. 
Published: August 2018

Contents

Summary
706

I.
Introduction
707

II.
Leaf zones in monocot and eudicot leaves
707

III.
Monocot and eudicot leaf initiation: differences in degree and
timing, but not kind
710

IV.
Reticulate and parallel venation: extending the model?
711

V.
Flat laminar growth: patterning and coordination of
adaxial–abaxial and mediolateral axes
713

VI.
Stipules and ligules: ontogeny of primordial elaborations
715

VII.
Leaf architecture
716

VIII.
Stomatal development: shared and diverged mechanisms
for making epidermal pores
717

IX.
Conclusion
719

Acknowledgements
720

References
720

SummaryComparisons of concepts in monocot and eudicot leaf development are presented, with attention to the morphologies and mechanisms separating these angiosperm lineages. Monocot and eudicot leaves are distinguished by the differential elaborations of upper and lower leaf zones, the formation of sheathing/nonsheathing leaf bases and vasculature patterning. We propose that monocot and eudicot leaves undergo expansion of mediolateral domains at different times in ontogeny, directly impacting features such as venation and leaf bases. Furthermore, lineage‐specific mechanisms in compound leaf development are discussed. Although models for the homologies of enigmatic tissues, such as ligules and stipules, are proposed, tests of these hypotheses are rare. Likewise, comparisons of stomatal development are limited to Arabidopsis and a few grasses. Future studies may investigate correlations in the ontogenies of parallel venation and linear stomatal files in monocots, and the reticulate patterning of veins and dispersed stoma in eudicots. Although many fundamental mechanisms of leaf development are shared in eudicots and monocots, variations in the timing, degree and duration of these ontogenetic events may contribute to key differences in morphology. We anticipate that the incorporation of an ever‐expanding number of sequenced genomes will enrich our understanding of the developmental mechanisms generating eudicot and monocot leaves.
Cell cycle acceleration and changes in essential nuclear functions induced by simulated microgravity in a synchronized Arabidopsis cell culture
Authors: Kamal Khaled Y. , Herranz Raúl , van Loon Jack J.W.A. , Medina F. Javier 
Published: August 2018

AbstractZero gravity is an environmental challenge unknown to organisms throughout evolution on Earth. Nevertheless, plants are sensitive to altered gravity, as exemplified by changes in meristematic cell proliferation and growth. We found that synchronized Arabidopsis‐cultured cells exposed to simulated microgravity showed a shortened cell cycle, caused by a shorter G2/M phase and a slightly longer G1 phase. The analysis of selected marker genes and proteins by quantitative polymerase chain reaction and flow cytometry in synchronic G1 and G2 subpopulations indicated changes in gene expression of core cell cycle regulators and chromatin‐modifying factors, confirming that microgravity induced misregulation of G2/M and G1/S checkpoints and chromatin remodelling. Changes in chromatin‐based regulation included higher DNA methylation and lower histone acetylation, increased chromatin condensation, and overall depletion of nuclear transcription. Estimation of ribosome biogenesis rate using nucleolar parameters and selected nucleolar genes and proteins indicated reduced nucleolar activity under simulated microgravity, especially at G2/M. These results expand our knowledge of how meristematic cells are affected by real and simulated microgravity. Counteracting this cellular stress is necessary for plant culture in space exploration.
The State of Mixed Methods Research in Public Administration and Public Policy
Authors: Hendren Kathryn , Luo Qian Eric , Pandey Sanjay K. 
Published: August 2018

AbstractPublic administration scholars have publicized the benefits of mixed methods research and exhorted researchers to embrace mixed methods research design. Despite increasing calls for and numbers of mixed methods publications, thus far there has been no rigorous assessment of the value added by mixed methods research designs. This article provides an assessment of mixed methods articles published in leading public administration and public policy journals. The authors assess methodological quality, study purpose, and research design in order to determine the added value of mixed methods research designs. Findings highlight the promise of mixed methods research in public administration and public policy. Realizing this promise will require better appreciation of the added benefits of mixed methods designs, dedicated effort to improve the qualitative component of mixed methods studies, and greater attention to integrating the qualitative and quantitative components of mixed methods studies.
Different doses of Pilates-based exercise therapy for chronic low back pain: a randomised controlled trial with economic evaluation
Authors: Miyamoto Gisela Cristiane , Franco Katherinne Ferro Moura , van Dongen Johanna M , Franco Yuri Rafael dos Santos , de Oliveira Naiane Teixeira Bastos , Amaral Diego Diulgeroglo Vicco , Branco Amanda Nery Castelo , da Silva Maria Liliane , van Tulder Maurits W , Cabral Cristina Maria Nunes 
Published: August 2018

ObjectivesTo evaluate the effectiveness and cost-utility of the addition of different doses of Pilates to an advice for non-specific chronic low back pain (NSCLBP) from a societal perspective.DesignRandomised controlled trial with economic evaluation.SettingPhysiotherapy clinic in São Paulo, Brazil.Participants296 patients with NSCLBP.InterventionsAll patients received advice and were randomly allocated to four groups (n=74 per group): booklet group (BG), Pilates once a week (Pilates group 1, PG1), Pilates twice a week (Pilates group 2, PG2) and Pilates three times a week (Pilates group 3, PG3).Main outcome measuresPrimary outcomes were pain and disability at 6-week follow-up.ResultsCompared with the BG, all Pilates groups showed significant improvements in pain (PG1, mean difference (MD)=−1.2, 95% CI −2.2 to −0.3; PG2, MD=−2.3, 95% CI −3.2 to −1.4; PG3, MD=−2.1, 95% CI −3.0 to −1.1) and disability (PG1, MD=−1.9, 95% CI −3.6 to −0.1; PG2, MD=−4.7, 95% CI −6.4 to −3.0; PG3, MD=−3.3, 95% CI −5.0 to −1.6). Among the different doses, PG2 showed significant improvements in comparison with PG1 for pain (MD=−1.1, 95% CI −2.0 to −0.1) and disability (MD=−2.8, 95% CI −4.5 to −1.1). The cost-utility analysis showed that PG3 had a 0.78 probability of being cost-effective at a willingness-to-pay of £20 000 per quality-adjusted life-year gained.ConclusionsAdding two sessions of Pilates exercises to advice provided better outcomes in pain and disability than advice alone for patients with NSCLBP; non-specific elements such as greater attention or expectation might be part of this effect. The cost-utility analysis showed that Pilates three times a week was the preferred option.Trial registration numberNCT02241538, Completed.