bluuebunny/crossref_metadata_2025_split huggingface dataset:
Providing Care to People With Intellectual and Developmental Disabilities in Medical Education
Authors: Lunsky Isis Olivia , Gutierrez Gilmar , Rabu Olivier , Gemmill Meg , Hamer Debra 
Published: October 2024

Abstract
Medical professionals commonly report having inadequate training providing care for individuals with intellectual and developmental disabilities (IDD). This pilot study aimed to address this gap through a virtual Objective Structured Clinical Examinations (OSCE) with individuals with IDD as patient educators for 25 first- and second-year medical students (OSCE participants). Quantitative data through the Prediger competency scale and qualitative data through a semistructured interview were analyzed. OSCE participants reported a significant increase (p &lt; 0.05) in self-perceived competency scores when comparing pre- and post-OSCE scores. Qualitative analysis yielded themes corresponding to improving skills, practice considerations, and perspectives and biases changes. These results suggested that this virtual OSCE promoted the development of self-perceived clinical competency and comfort providing care for individuals with IDD.
Examining Sociodemographic Variability in the Amount and Type of Interventions for Children With Autism
Authors: Durham Hannah S. , Bowman Karrah L. , Harrison Ashley J. 
Published: October 2024

Abstract
Various intervention usage is associated with positive outcomes for children with autism. However, the intensity of these interventions tends to be below recommendations, especially for minoritized children. This study aimed to examine how average weekly intervention hours among children vary by sociodemographic factors. Regression analyses were conducted using data from 2,857 participants with autism included in the Simons Simplex Collection. Findings indicated the amount and type of intervention received varied by race, ethnicity, family income, and maternal education. This study marks an important step in documenting the extent of sociodemographic intervention disparities; and, helps to elucidate which therapy types are most readily underused and by which groups to help inform approaches to increase more equitable access.
Advanced Quantum Detectors via Advanced Quantum Trickery
Authors: Kwiat Paul 
Published: October 2024

One advantage of correlated photons from nonlinear processes is that they can have very wide spectra and very narrow time correlations. However, the value of these is lessened if not lost altogether because of detector limitations. Here we will describe our progress on some new ideas to improve detector performance. Well, new-ish.
Full-text article not available; see video presentation
Level of burnout and associated factors among healthcare workers in central Uganda: A facility-based cross-sectional study
Authors: Kabunga Amir , Kigongo Eustes , Musinguzi Marvin , Tumwesigye Raymond , Akello Anne Ruth , Acup Walter , Asiimwe Mary Gorretti , Nalwoga Viola 
Published: October 2024

Background
Burnout among healthcare workers is a global concern with significant implications for both the well-being of the workforce and the quality of patient care. This facility-based cross-sectional study aimed to identify factors associated with burnout among healthcare workers in central Uganda.

Methods
The study, conducted between June and July 2023, utilized a cross-sectional design involving physicians, nurses, and technicians. The study covered both public and private hospitals in central Uganda, incorporating urban and rural settings. A sample size of 550 healthcare workers was selected using a simple random sampling. Data collection involved a socio-demographic survey, the Professional Quality of Life (ProQOL-5). Descriptive statistics, Pearson Chi-square test, and ordinal regression models were employed to analyze demographic factors associated with burnout.

Results
Of 548 participants, 218(39.8%) experienced high burnout levels. Factors significantly associated with high burnout levels included having over 10 years of work experience (OR: 2.04, 95% CI: 1.12–3.73), working more than 40 hours per week (AOR: 4.46, 95% CI: 1.20–16.62), lack of management support (AOR: 14.45, 95% CI: 3.83–54.56), not experiencing workplace violence (AOR: 2.22, 95% CI: 1.31–3.76), and reporting inadequate sleep (AOR: 6.96, 95% CI: 3.86–12.57).

Conclusion
Addressing burnout among healthcare workers in central Uganda requires targeted interventions tailored to the specific challenges faced in the region, including workload distribution, managerial support enhancement, violence prevention strategies, and promotion of adequate sleep. Urgent attention to these factors is essential for enhancing the well-being of healthcare professionals and maintaining quality patient care.
Impact of CA9 expression in the diagnosis of lymph-node metastases in non-small cell lung cancer based on [18F]FDG PET/CT
Authors: Suzuki Satoshi , Yashiro Masakazu , Izumi Nobuhiro , Tsukioka Takuma , Inoue Hidetoshi , Hara Kantaro , Ito Ryuichi , Tanimura Takuya , Nishiyama Noritoshi 
Published: October 2024

Background
Lung cancer is the leading cause of the global cancer incidence and mortality. It is important to obtain an accurate diagnosis of lymph-node metastasis before surgery to select the therapeutic strategy for non-small cell lung cancer (NSCLC) patients. Carbonic anhydrase 9 (CA9) is considered a marker of hypoxia and it has reported that CA9 is associated with tumor invasion and metastasis. In this study, the correlation between the CA9 expression for lymph-node metastases in NSCLC and [18F]FDG PET/CT results was investigated in order to clarify the efficacy of [18F]FDG PET/CT for detecting lymph-node metastases of NSCLC patients.

Methods
Among the 564 patients who underwent surgical treatment for NSCLC between 2010 and 2016 at our hospital, a total of 338 patients who underwent preoperative [18F]FDG PET/CT were included in this study. CA9 expression was evaluated by immunochemistry. A lymph node with maximum standardized uptake value (SUVmax) ≥2.5 on [18F]FDG PET/CT was preoperatively defined as a metastatic lymph node.

Result
CA9 positivity was detected in 122 patients; the other 216 patients were CA9-negative. The CA9-positive NSCLC cases significantly associated with pleural invasion (p = 0.0063), pT-factor (p = 0.0080), pN-factor (p = 0.036) and pStage (p = 0.043). CA9-positive patients presented significantly poorer survival rate for OS than that of the CA9-negative patients (p = 0.0024). In the multivariable analysis, histological SCC and CA9 positivity were independent poor-prognosis factors for OS. For the total patient population, the sensitivity and specificity of [18F]FDG PET/CT for lymph-node metastases were 54% and 89%, respectively. In contrast, the sensitivity and specificity were particularly low in the CA9-positive SCC cases (36% and 69%, respectively).

Conclusion
[18F]FDG PET/CT might not be useful for diagnosing lymph-node metastases of CA9-positive SCC cases of NSCLC.
Audit of antibiotic utilization patterns and practice for common eye infections at the ambulatory clinic of a teaching hospital in Ghana: Findings and implications
Authors: Sefah Israel Abebrese , Quagraine Anthony Martin , Kurdi Amanj , Mudenda Steward , Godman Brian 
Published: October 2024

Background
Antimicrobial resistance (AMR) is a serious public health issue which is exacerbated by increased inappropriate use of antibiotics for common eye infections. This cross sectional survey was to assess the appropriate use of antibiotics for eye infections in an ambulatory clinic in Ghana and possible determinants.

Method
The medical records of all patients who sought eye care between January 2022 to December 2022 and were prescribed antibiotics were extracted from the hospital’s electronic database. Descriptive, bivariate and multivariate analyses were then conducted.

Results
A total of 1925 patient medical records were extracted, whose median age was 40 years (IQR 26–69), and were mostly females (58.91%, n = 1134/1925). The eye condition commonly treated with antibiotics was bacteria conjunctivitis (33.51%, n = 645/1925). The most prescribed antibiotic was gentamycin (22.96%, n = 442/1925) followed by ciprofloxacin (16.78%, n = 321/1925). These were mostly topical dosage forms (82.13%, n = 1581/1925). Systemic antibiotics prescribed were mostly from the WHO ‘Access’ class (83.33%, n = 280/338). The appropriate choice of antibiotic prescribed was 42.44% (n = 817/1925) and this was positivity associated with age (p<0.001), number of antibiotics prescribed (p <0.001), the prescription of topical dosage forms (p <0.001), and WHO ‘Access’ antibiotic class (p <0.034).

Conclusion
The level of appropriateness of antibiotic prescriptions for eye infections was sub-optimal. Antimicrobial stewardship programs, including prescriber education on guidelines and prescription audit to address associated factors, must now be instigated in this hospital to improve future antibiotic use and prevent the rise of AMR.
Gangguan Pendengaran pada Anak dengan Sindrom Bartter
Authors: Muyassaroh Muyassaroh , Pratomo Santo Mudha , Muryawan Heru 
Published: October 2024

Latar belakang. Sindrom Bartter merupakan gangguan tubulus ginjal ditandai dengan hiperaldosteronisme sekunder, alkalosis metabolik hipokalemia, disertai tekanan darah yang normal atau rendah. Gangguan elektrolit akibat kelainan ginjal, berpengaruh pada telinga bagian dalam mengakibatkan gangguan pendengaran. Tujuan. Mengetahui gangguan pendengaran pada anak dengan Sindrom Bartter. Metode. Dilakukan pencarian di PubMed, Google Schoolar, dan Cochrane dengan menggunakan kata kunci “Hearing loss”, “barter syndrome”, dan “hypokalemia”. Hasil pencarian dievaluasi menggunakan kriteria eksklusi dan inklusi. Selanjutnya dilakukan telaah kritis dengan memperhatikan validitas, kepentingan dan penerapan pada pasien terhadap artikel lengkap dari studi yang terseleksi. Hasil. Diperoleh satu studi yang relevan dengan pertanyaan klinis dan memenuhi kriteria inklusi dan eksklusi. Luaran dari studi ini memperlihatkan bahwa terdapat pengaruh gangguan pendengaran pada pasien dengan Sindrom Bartter.Kesimpulan. Gangguan elektrolit pada anak dengan Sindrom Bartter memengaruhi pendengaran. Tata laksana farmakologi dan rehabilitasi dapat mengatasi gangguan komunikasi yang terjadi.
Pengaruh Self-Congruity Pengguna Smartphone terhadap Brand Trust melalui Brand Experience sebagai mediator
Authors: Al Ihsan Ibtihajar Mangputri , Chrisjatmiko Kurniawati 
Published: October 2024

This research is proposed to determine the influence of self-congruity from actual, ideal and social self-congruity aspects on brand trust mediated by brand experience. The survey was conducted on individuals in Indonesia who use one of the smartphone brands with the largest market share in the country, namely Oppo, Samsung, Xiaomi, Vivo, Apple, Realme, Infinix and Asus. The total samples obtained was 279. The sampling method was carried out by purposive sampling with a cross-sectional way. The model fit test uses Structural Equation Modeling (SEM) as a requirement to continue with hypothesis testing. The results of the study show that there is an influence of actual self-congruity, ideal self-congruity, and social self-congruity on brand trust mediated by brand experience. Moreover, this research also proves that brand experience has an influence towards brand trust.Penelitian ini diajukan untuk mengetahui pengaruh self-congruity dari aspek actual, ideal dan social self-congruityterhadap brand trust yang dimediasi oleh brand experience. Survei dilakukan terhadap individu di Indonesia yang menggunakan salah satu merek smartphone dengan pangsa pasar terbesar, yaitu Oppo, Samsung, Xiaomi, Vivo, Apple, Realme, Infinix atau Asus.Jumlah sampel yang diperoleh adalah 279. Metode pengambilan sampling dilakukan dengan purposive sampling dengan cara cross-sectional. Pengujian kesesuaian model menggunakan Structural Equation Modelling (SEM) sebagai syarat agar kemudian dapat dilakukan pengujian hipotesis. Hasil dari penelitian menunjukkan bahwa terdapat pengaruh actual self-congruity, ideal self-congruity, dan social self-congruity terhadap brand trust yang dimediasi oleh brand experience. Selain itu, penelitian juga membuktikan bahwa brand experience memiliki pengaruh terhadap brand trust.
SLIT3 deficiency promotes non-small cell lung cancer progression by modulating UBE2C/WNT signaling
Authors: Qiu Zidan , Zhan Ying , Chen Zhiyong , Huang Wenjin , Liao Jianrong , Chen Zhen , Zheng Junqiong , Zheng Qiuxiang , Lu Cuiping 
Published: October 2024

Abstract
In our prior research, it was noted that slit guidance ligand 3 (SLIT3), a member of the SLIT-secreted protein family, may play a potential role in tumorigenesis. In addition, our prior work has found that the SLIT3 gene is highly methylated, especially in advanced-stage lung cancer tissues. Herein, we propose the hypothesis that abnormal SLIT3 expression may be linked to lung cancer development. In this study, decreased SLIT3 at the transcriptome and proteome levels was observed in lung cancer tissues. Furthermore, the downregulation of SLIT3 was related to a higher tumor stage and poorer prognosis. Silencing SLIT3 expression enhanced cell proliferation and migration, indicating potential characteristics of a tumor suppressor gene of SLIT3 in non–small-cell lung cancer (NSCLC). Furthermore, SLIT3 deficiency stimulates UBE2C upregulation and regulates NSCLC progression through Wnt3A/β-catenin signaling. The activation of the WNT signaling pathway was highly correlated with chemoresistance development in lung cancer. In conclusion, SLIT3 deficiency promotes lung cancer onset and progression by modulating UBE2C/WNT signaling. SLIT3/UBE2C/WNT may serve as novel biomarkers and therapeutic targets in NSCLC.
Meaning-making in English-medium instruction science classroom interaction: from the systemic functional linguistics perspective
Authors: Pun Jack , Jia Wenyun 
Published: October 2024

Abstract
Teaching science in English is increasingly common worldwide. This study explores the role of language in science meaning-making during classroom interactions by drawing on video-recorded classroom observations of four biology lessons in secondary English medium instruction (EMI) settings in Hong Kong. Informed by systemic functional linguistics (SFL), we integrate classroom interaction analysis with Lemke’s approach to thematic analysis. The results reveal similar interactional patterns across full- and partial-EMI science classrooms, characterised by a lack of interactivity and authoritative teacher behaviour in selecting student responses to engage with. During extended initiation–response–feedback exchanges, teachers’ feedback on students’ responses appears to underscore the importance of teachers’ modified input – specifically input emphasising semantic relations within the field of biology – in developing students’ content knowledge and language skills. The implications of the findings for applying SFL pedagogies in EMI science classrooms to improve teacher–student interaction are discussed.
Effects of the Strong Hearts program at two years post program completion
Authors: Murphy Bruce E. , Card Peyton D. , Ramirez-Kelly Leybi , Wensley Brandon , Heidel Robert E. 
Published: October 2024

Abstract

Context
This is a follow-up to the original published article, Effects of the Strong Hearts Program after a Major Cardiovascular Event in Patients with Cardiovascular Disease.

Objectives
This study evaluated the long-term efficacy of the Strong Hearts program up to 2 years after program completion.

Methods
All study participants who initially completed the Strong Hearts program between 2020 and 2021 (n=128) were contacted at 12 months and 24 months following the date of program completion. A phone survey was conducted to see if any significant post-cardiovascular events or readmissions to the hospital occurred, and self-reported dates of any occurrences were recorded. Hospital readmissions and cardiac-related procedures were cross-referenced with the hospital’s electronic medical record. A chi-square goodness-of-fit analysis was utilized to compare the observed rates of categorical outcomes vs. expected rates yielded from the empirical literature.

Results
The rate of all-cause readmission at 6 months post-program completion was 2/120 (1.7 %), compared to the expected rate of 50 %, χ2(1) = 112.13, p<0.001. The readmission rate at 1 year post-program completion was 17/120 (14.2 %), vs. the expected rate of 45 %, χ2(1) = 46.09, p<0.001, and at 2 years post-program completion, the readmission rate was 24/120 (20.0 %) compared to the expected rate of 53.8 %, χ2(1) = 56.43, p<0.001. Ten participants (8.3 %) had a subsequent cardiac procedure within 2 years of completing the program, including two requiring percutaneous coronary intervention (1.7 %) and eight requiring coronary artery bypass grafting (CABG, 6.7 %), compared to the expected rates of 13.4 and 57.74 %, χ2(1)=153.08, p<0.001, respectively. Mortality at 2 years post-program completion was 2/128 (1.6 %), compared to 23.4 %, χ2(1)=34.13, p<0.001.

Conclusions
Efficacy of the Strong Hearts program continued at 6 months, 1 year, and 2 years post-program completion in terms of all-cause readmission, subsequent cardiac event, and all-cause mortality.
Understanding content dissemination on sensemaking: WHO’s social listening strategy on X during the initial phase of COVID-19
Authors: Kumble Sushma , Diddi Pratiti , Bien-Aimé Steve 
Published: October 2024

Abstract

Purpose
Guided by the Crisis and Emergency Risk Communication model (CERC, Reynolds and Seeger 2005. Crisis and emergency risk communication as an integrative model. Journal of Health Communication 10(1). 43–55.), the present study aimed to study how X (formerly Twitter) users sensemaking and efficacy based message. Additionally, the study also aimed to understand how the World Health Organization (WHO) responded to the emerging conversation.

Methods
Unsupervised machine learning was conducted on 6.1 million tweets between January and March 2020 to understand sensemaking about COVID-19 among X users. Additionally, content analysis was used to examine if the World Health Organization (WHO) responded to popular emerging conversations via content on their own X handle.

Findings
The majority of dominant topics in COVID-19 tweets from January to March 2020 related to understanding the virus and the crisis it caused. X users tried to make sense of their surroundings and re-create their familiar world by framing events. Content analysis revealed that WHO engaged in effective social listening and responded quickly to dominant X conversations to help people make sense of the situation.

Practical Implications
The initial stage of COVID-19 pandemic was marked with uncertainty. However, WHO had a robust communication strategy and addressed the dominant conversation during the time frame including debunking misinformation.

Originality/Value
The present study fills the research gap by situating the themes in the context of the health crisis and extending the CERC model to user-generated content via the lens of sensemaking and efficacy messages during the COVID-19 pandemic. Additionally, the study segmented the timelines into smaller time intervals to understand how sensemaking evolved over time.
Aktualisasi dan Implementasi Meaningfull Learning dan Powerfull Learning dalam Pembelajaran Wawasan IPS di Indonesia
Authors: Irrubai Mohammad Liwa 
Published: October 2024

Tulisan ini bertujuan untuk menjelaskan bahwa dalam proses pembelajaran dosen dituntut mampu menerapkan metode dan model pembelajaran yang sesuai dengan kondisi mahasiswa, hal ini berpengaruh dalam proses pembelajaran karena sering terjadi dosen kurang memahami model dan metode pembelajaran yang harus digunakan sehingga pada mata kuliah seperti Wawasan IPS yang memiliki materi yang banyak tidak tersampaikan dengan maksimal. Untuk mengatasi hal tersebut, pembelajaran dengan meaningfull learning dan powerfull learning merupakan model yang dapat dijadikan alternatif untuk memberikan pemahaman secara kognitif, afektif maupun psikomotorik kepada mahasiswa dengan kemampuan yang berbeda-beda. Penelitian ini menggunakan pendekatan kualitatif dengan metode penelitian deskriptif. Pengumpulan data: participant observation, in-depth interviews, dan documentation. Analisis data menggunakan Miles dan Huberman. Hasil penelitian menunjukkan bahwa pembelajaran Wawasan IPS di UIN Malang menerapkan meaningfull learning dan powerfull learning dengan menggunakan motode project dan problem solving, sedangkan di UIN Mataram menggunakan metode inkuiri, dengan penerepan kedua metode tersebut mahasiswa dilatih belajar dengan menggunakan kemampuan kognitif, afekt dan psikomotorik secara efektif. Kata Kunci: Meaningfull Learning, Powerfull Learning, Pembelajaran Wawasan IPS
Differences in Pediatricians’ Income by Sex Over Time
Authors: Frintner Mary Pat , Freed Gary L. , Byrne Bobbi J. , Leslie Laurel K. , Starmer Amy J. , Gottschlich Elizabeth A. , Olson Lynn M. 
Published: October 2024

OBJECTIVE
Previous Pediatrician Life and Career Experience Study (PLACES) 2016 data revealed that female pediatricians reported earning ∼94% of what male pediatricians reported, after adjusting for factors that might impact income. Has this disparity persisted?

METHODS
Data from PLACES, a national longitudinal study, was used to examine pediatrician-reported income from 2017 to 2022. A regression analysis estimated the adjusted differences in female and male pediatricians’ annual income for each survey year. Models included sex and other key personal and practice characteristics for which female and male pediatricians’ careers might differ. A mixed effects regression for longitudinal analysis examined income across years for female and male pediatricians and if time-variant characteristics are associated with increased or decreased income.

RESULTS
PLACES participation ranged from 83.6% in 2017% to 75.5% in 2022 (analytic n = 1251 in 2017 and 1077 in 2022). The unadjusted mean annual income in 2022 was $237 168, $220 374 for female pediatricians and $284 286 for male pediatricians. Adjusting for key characteristics, female pediatrician income was ∼93% of male pediatrician income, a gap of ∼$ 11 000 annually. Income increased across years (coefficient = 0.03, P &lt; .001). The year–sex interaction was not significant, indicating that the female–male disparity did not change over time. Three time-variant characteristics associated with increased income over time included increased portion of continuous full-time work, work hours, and time in administrative work.

CONCLUSIONS
A national longitudinal study revealed that female pediatricians reported earning ∼93% of what their male colleagues reported, with a consistent gap from 2017 to 2022.
Enhancement of a heat pump's efficiency COP operating on the water-soil principle
Authors: Brbhan Salman , Omle Issa , Szamosi Zoltán 
Published: October 2024

AbstractGeothermal energy is increasingly promising for residential use due to rising energy costs and environmental awareness. This work experimentally examines the impact of pipe distribution on the heat pump's performance at varying temperatures for both the incoming water and the ground. The pipes are buried in the soil, distributing them on layers of varying depths up to a depth of 2 m, separated by insulating layers. The quantities of heat gained in the evaporator and released in the condenser are calculated to determine the coefficient of performance of the heat pump. It was found that at the same temperature, the total heat loss in the soil is larger in the case of water entering from the bent pipe towards the great depth compared to water entering from the direct pipe, but the heat gain is larger in the case of water entering from the direct one.