bluuebunny/crossref_metadata_2025_split huggingface dataset:
Educação para a sustentabilidade em contextos urbano-periféricos: a experiência do LAURBS em Juazeiro do Norte, Ceará
Authors: Nascimento Diego Coelho do , Torres Geovane Gesteira Sales , Silva Caio Ricardo da , Cruz Regina Pimentel 
Published: November 2024

O presente artigo tem como objetivos relatar e analisar a experiência do Laboratório de Estudos Urbanos, Sustentabilidade e Políticas Públicas (LAURBS) em relação às atividades de extensão universitária relacionadas à educação para a sustentabilidade no bairro João Cabral, em Juazeiro do Norte – CE, no ano de 2019. Para tanto, a presente pesquisa exploratória, cujos seus meios a configuram como uma pesquisa-ação, adotou como método de coleta de dados a observação etnográfica, possuindo, ainda, um tratamento de natureza qualitativa de tais informações. Mediante tal fluxo, constataram-se realidades educacionais “bancárias”, por parte das escolas presentes no bairro, além de inúmeras realidades degradantes dos residentes na localidade, sobretudo no que se refere a direitos, bens e serviços fundamentais, destacando-se as mazelas tocantes à segurança pública, saúde e meio ambiente. Portanto, exalta-se a relevância da extensão universitária no que se refere à promoção da dignidade humana e procura por realidades mais benfazejas em territórios subdesenvolvidos.
As mídias digitais na formação continuada de professores da educação especial
Authors: Rodrigues Rosangela Ferreira , Lopes Lucas Schneider , Camelo Júnior Francisco de Assis Araújo , Rodrigues Anderson Ferreira , Murari Anelise Levay , Makiyama Bruno Kendi 
Published: November 2024

A Lei de Diretrizes e Bases da Educação Brasileira (LDB) define que a educação especial deve preferencialmente, ser oferecida pela rede básica de ensino, através de professores com especialização adequada para realizar a integração dos educandos. Para auxiliar nesse desafio atualmente existem muitos recursos tecnológicos, que podem contribuir para o processo de aprendizagem, entretanto, alguns docentes apresentam dificuldade em utilizar esses recursos. Portanto, proporcionar o conhecimento de programas, aplicativos, domínio de navegação pela internet e suas ferramentas, favorece a incorporação desses recursos ao processo de ensino-aprendizagem. Perante o exposto, o objetivo do projeto foi proporcionar formação continuada aos professores de uma Escola de Educação Especial da cidade de Pelotas, para diminuir a prevalência de docentes não familiarizados com as tecnologias de informação e comunicação (TICs) e incentivar a sua utilização. O projeto ocorreu no ano de 2019 com participação de discentes e docentes da Universidade Federal de Pelotas (UFPel). Para melhor compreensão, o conteúdo foi distribuído em três oficinas que foram realizadas uma vez por mês, totalizando três meses. As oficinas possibilitaram a atualização em recursos tecnológicos, para implementação no processo de ensino-aprendizagem e em contrapartida permitiram aos acadêmicos da universidade vivenciarem a realidade do sistema de ensino, com seus entraves, superações e troca de saberes que certamente causaram impacto em suas percepções. A criatividade de alguns professores em ultrapassar barreiras, para tornar o conteúdo compreensível, foi inspirador e mostrou o potencial que existe em nossas escolas, que poderiam se tornar um diferencial se melhores condições de trabalho fossem ofertadas.
Ensino de química e libras: reflexões a respeito da educação de surdos
Authors: Passinato Cristiana de Barcellos , Gomes Eduardo Andrade , Pereira Kevin Lopes , Bozzi Raquel Alves , Ferreira Nathália Barros 
Published: November 2024

O trabalho em questão trata-se de uma ação do projeto de extensão universitária denominado “Acessibilidade em tempos de quarentena e a Covid-19” da sessão de Acessibilidade do IQ-UFRJ. O evento foi realizado envolvendo os autores, culminando em uma apresentação em formato de live, devido a atual pandemia vivida. O objetivo desse projeto é realizar, dentre outras ações, comunicações em formato virtual para difundir informações e gerar saudáveis debates entre a comunidade universitária e o público em geral, sobre a questão da inclusão e da acessibilidade, principalmente no contexto contemporâneo e mundial. A live em pauta consistiu em uma atividade resultante de um processo extremamente cuidadoso, em que estudantes e profissionais debateram aspectos relacionados ao ensino de Química e à Língua Brasileira de Sinais (Libras). Tal sistematização circunscreveu a apresentação, em Libras, com interpretação simultânea para o Português, de quatro perspectivas em torno da educação Química para surdos, a saber, (i) experiências quanto à atividades em um projeto de extensão de educação bilíngue; (ii) a semiótica na sala de aula inclusiva a surdos; (iii) a formação de professores de Ciências da Natureza e a educação de surdos; e (iv) a relação entre os professores e os intérpretes educacionais de Libras-Português em sala de aula; seguida de uma discussão com os espectadores. O resultado foi gratificante para todos os envolvidos, em virtude da possibilidade de reunir e compartilhar atuais e relevantes questões no que tange ao ensino de Química para surdos.
Gender-affirming hormone therapy: effects on cardiovascular risk and vascular function
Authors: McGinley Kirsty A , Lucas-Herald Angela K , Connelly Paul , Delles Christian 
Published: November 2024

Graphical abstractGender-affirming hormone therapy and cardiovascular disease risk in transgender individuals. CIMT, carotid intima–media thickness. CVD, cardiovascular disease. FMD, flow-mediated dilatation. PWV, pulse wave velocity. TGM, transgender men. Created using BioRender.com.AbstractBackgroundGender-affirming hormone therapy (GAHT) is used in individuals with gender identity dysphoria to align their secondary sexual characteristics with their affirmed gender. We conducted a systematic review of the literature to explore the mechanisms regarding the effects of GAHT on the vasculature.MethodsA literature search using PubMed, Embase, Scopus and LILACS was performed using search terms for GAHT, cardiovascular disease (CVD) risk and transgender. Studies were screened by two independent reviewers. Comparison to a cohort of transgender individuals naive or prior to GAHT or a cisgender population was required. Quality assessment was done using the relevant Critical Appraisal Skills Programme checklists.ResultsOut of 2,564 potentially eligible studies, 69 studies met the inclusion criteria. Studies provided evidence of beneficial changes in CVD risk profile, including reduced haemoglobin and pro-inflammatory markers, and atheroprotective changes in lipids in transgender women. In transgender men, there was evidence of negative changes in CVD risk profile, including atherogenic changes in lipids and increased haemoglobin, arterial stiffness and pro-inflammatory markers.ConclusionsThere is a paucity of research across non-traditional measures of CVD risk, which in combination with heterogeneous study design, loss of follow-up, low sample sizes and lack of diversity in age and ethnicity requires the results to be interpreted with caution. More evidence is required to elucidate the mechanisms behind the increased risk of CVD in the transgender population and determine whether GAHT is a contributing factor.
Teaching Residents at Night: Exploration of a Novel Curriculum
Authors: Heller Kayla , Ermer Jonathan , Etzenhouser Angela , Schuetz Nik , Hurley Emily A. 
Published: November 2024

BACKGROUND
Implementation of a successful night curriculum has been a historical barrier to education during night rotations. Residents are tasked with teaching students and peers at night, often with little educational material to support this. To address the need for engaging night curriculum for pediatric residents, we aimed to (1) develop and implement a night curriculum with an emphasis on residents as teachers (RaTs) and (2) explore residents’ experience with the RaT curriculum through a secondary qualitative analysis of reflections.

METHODS
After a needs assessment, we developed and implemented a night curriculum consisting of both facilitated and independent learning activities. Each resident was expected to complete 3 out of the offered 5 to 7 learning activities during their month-long night rotation. One independent activity featured RaT topics, including clinical teaching, mentoring, or hidden curriculum. Participation was tracked via reflection submissions, which were inductively coded using Dedoose.

RESULTS
A total of 90% (180/199) of resident rotations completed new curriculum requirements, with 45% (90/199) completing more than the required 3 activities. A total of 76% (151/199) chose to participate in the RaT activity as part of their night educational requirements. A total of 52 reflection responses were collected, 38 individual and 14 team responses. Responses highlighted themes including growing as educators, fostering interprofessional relationships, and developing careers.

CONCLUSIONS
High participation in the novel curriculum reveals the potential of virtual RaT activities to improve night education for residents. Participant reflections suggest high engagement in RaT and emphasize the andragogical value of key topics.
Cost-Effectiveness of Maternal Vaccination to Prevent Respiratory Syncytial Virus Illness
Authors: Hutton David W. , Prosser Lisa A. , Rose Angela M. , Mercon Kerra , Ortega-Sanchez Ismael R. , Leidner Andrew J. , McMorrow Meredith L. , Fleming-Dutra Katherine E. , Prill Mila M. , Pike Jamison , Jones Jefferson M. 
Published: November 2024

BACKGROUND AND OBJECTIVES
Respiratory syncytial virus (RSV) commonly causes hospitalization among US infants. A maternal vaccine preventing RSV in infants, RSV bivalent prefusion F maternal vaccine (RSVpreF), was approved by the US Food and Drug Administration and recommended by the Advisory Committee on Immunization Practices. Our objective was to evaluate the health benefits and cost-effectiveness of vaccinating pregnant persons in the United States using RSVpreF.

METHODS
We simulated RSV infection and disease with and without seasonal RSVpreF vaccination in half of the pregnant persons in the annual US birth cohort during weeks 32 through 36 of gestation. Model inputs came from peer-reviewed literature, Food and Drug Administration records, and epidemiological surveillance databases. The results are reported using a societal perspective in 2022 US dollars for a 1-year time frame, discounting future health outcomes and costs at 3%. Sensitivity and scenario analyses were performed.

RESULTS
Year-round maternal vaccination with RSVpreF would prevent 45 693 outpatient visits, 15 866 ED visits, and 7571 hospitalizations among infants each year. Vaccination had a societal incremental cost of $396 280 per quality-adjusted life-year (QALY) saved. Vaccination from September through January cost $163 513 per QALY saved. The most influential inputs were QALYs lost from RSV disease, the cost of the vaccine, and RSV-associated hospitalization costs; changes in these inputs yielded outcomes ranging from cost-saving to $800 000 per QALY saved.

CONCLUSIONS
Seasonal maternal RSV vaccination designed to prevent RSV lower respiratory tract infection in infants may be cost-effective, particularly if administered to pregnant persons immediately before or at the beginning of the RSV season.
Sports motivation and sports opportunities of people with physical disability: The case of Hungary
Authors: Tóth Bernadett , Máté Tünde 
Published: November 2024

AbstractThis article examines the sports motivation and sports opportunities of people with physical disability in Hungary, filling a gap in the research area. A total of 122 people (76 athletes) participated in the questionnaire research. We supplemented the quantitative research with qualitative research, in which we assessed the experiences of sports leaders through expert interviews. As a result of the research, we have shown that gender affects participation in sports, but has no role in sports motivation. Furthermore, we have established that for athletes with reduced mobility, mostly external motivational factors are different. Intrinsic motivation is strongest in the case of paralympic athletes. The main reason for amotivation among non-athletes with reduced mobility is the lack of adequate sports facilities close to the place of residence. Most athletes get to the venue of their sporting activity by car alone. Lack of peers has also been found to be a common reason for amotivation among respondents. Organising inclusive and mixed sports events could be a solution to the problem, promoting involvement in sport and social integration.
A Polish Pianist Travels to Budapest: “Affective Geography” in Bruno Monsaingeon's Piotr Anderszewski: Voyageur intranquille (2009)
Authors: Downes Stephen 
Published: November 2024

AbstractIn Bruno Monsaingeon's 2009 film portrait of Piotr Anderszewski cinematic technique, voice-over commentaries and musical performances combine to create an “affective” geography in which the pianist moves between significant Central Eastern European places. Anderszewski is filmed traveling in a special train carriage (including a grand piano) which, the director said, “as a place of meditation and reflection … would facilitate the use of flashbacks.” Memory, identity, and origins become central to the film's symbolism. After Freud, railway journeys can be interpreted as a privileged “analogy” for unconscious and repressed thought processes. Train metaphors may thus facilitate an imaging of the mental apparatus and its “lines of conduction.” The essay focuses on three symbolic locations in Anderszewski's journey – Warsaw, Budapest and Zakopane – and on performances of music by Chopin, Schumann and Szymanowski (the first heard in the railway carriage, the second in the Liszt Academy, Budapest, and the third in Szymanowski's house in Zakopane). Each of these sites and musical examples are interpreted primarily through Freud's notion of “displacement” to reveal counterpoints and conjunctions of displaced musical “voices” and identities. These hearings reveal the complexities and dissonances between Monsaingeon's French vision of “Eastern” Europe and Anderszewski's Polish-Hungarian self-identity as “Central” European cosmopolitan.
Polystylistic Traits in Ede Terényi's Music: The Baroque Concertos
Authors: Andreica Oana 
Published: November 2024

AbstractThis paper presents some aspects concerning a group of works written by Ede Terényi in the 1980s, a time in which composers were preoccupied with regaining a certain expression through the revival of the musical past. Romania was not an exception to this orientation, and composers applied the same technical devices as their Western colleagues, such as quotation, collage, allusion, pastiche, etc. This stylistic approach provided Terényi with the opportunity to find ways for the reconciliation of the European canon with the musical tradition of his native Transylvania, a reconciliation that was meant to make music accessible and beautiful again. He composed a series of twelve concertos for various instrumental combinations, in which the Baroque formal and expressive strategies meet the folkloric idioms of the central Romanian multiethnic region.
Building a roadmap for safer and sustainable material chemistries: Addressing the PFAS problem through informatics and data-driven chemistry
Authors: Fong Arthur , McPherson Alexandra , Rossi Mark , Rajan Krishna 
Published: November 2024

Abstract
Scientific research increasingly demonstrates that chemicals and materials essential for everyday products threaten natural systems and human health. Transitioning to sustainable, circular, and low-carbon economies depends critically on having safer chemicals available. We propose that materials scientists should also account for the impact of the health hazards of chemicals associated with the synthesis, processing, and manufacturing of materials. These include molecular precursors for synthesis of new materials chemistries and chemicals used in various stages of materials processing and manufacturing such as solvents and persistent, accumulative, and highly hazardous chemicals. Per- and polyfluoroalkyl substances are examples of harmful chemicals that pose health and environmental risks. A major challenge is finding safer yet functional alternatives that also meet the necessary performance requirements in sustainable materials design and development. The exploration space to discover these is prohibitively large to explore. Hence, we are at a critical inflection point and a paradigm shift is needed to include the development of safer chemicals as part of the equation to accelerate the adoption of safer and more sustainable chemical materials. Using such chemicals as an example, we describe an accelerated data-driven framework for designing safer material chemistries that ensures technical functionality and provides a holistic approach to sustainability.

Graphical abstract

Highlights
The development of sustainable materials needs to take into account the chemicals that appear at different stages of material synthesis, processing, and manufacturing, including molecular precursors, solvents, and PFAS containing compounds. We describe an accelerated data-driven framework for designing safer material chemistries that also accounts for the impact of chemicals to ensure technical functionality and provide a holistic approach to sustainability.

Discussion
To create a safer and sustainable materials ecosystem rapidly, one must address many competing and conflicting environmental, economic, and social consequences, requiring a new paradigm for materials research. We argue that materials informatics provides a framework to meet an expanded definition of materials performance that includes multiple metrics of functionality and the safety of chemicals used in materials synthesis, processing, and manufacturing. The power of this new research paradigm for materials innovation lies in discoveries that make it more feasible to address environmental and social impacts at the front end of material discovery, design, and deployment.
Appreciation of Black Humour Memes in the Context of the Russo-Ukrainian War
Authors: A'Beckett Ludmilla 
Published: November 2024

This study examines three black humour memes and their reception on social media during the 2022 Russian full-scale invasion of Ukraine. It seeks to identify the conditions that facilitate or impede the appreciation of jokes about the enemy’s death. Conceptual integration theory and Bandura’s social cognitive theory of moral agency provide the methodological framework for analysing the memes, and the responses to them. The findings offer an explanatory model for understanding when aggressive jokes are well-received or rejected. Successful humour transactions often involve humourists providing cues that encourage viewers to deactivate empathy towards the joke’s target. These cues may include euphemistic labelling, dehumanisation, or shared conventions about the consequences of the humour. Such triggers align with Bandura’s patterns of moral disengagement. The interaction between these triggers and the background knowledge of the audience can either lead to the appreciation of the humour or a conflict of values that results in the joke being dismissed. Humour is generally well-received when both the humourists and the audience agree on the need to undermine the power of the target and believe in the delivery of retribution for perceived wrongs. Conversely, if the target is perceived as valiant or vulnerable, the humour is often rejected as offensive or in poor taste.
Bilateral urothelial carcinoma of the renal pelvis
Authors: Gilivanova G. V. , Kipriyanov E. A. , Karnaukh P. A. , Ivakhno K. Yu. , Peretrukhin A. A. , Zolotykh M. A. , Beydzhanov M. T. , Rostovtsev D. M. 
Published: November 2024

Urothelial carcinoma is the 4th most prevalent malignant tumor after prostate (or breast), lung and colorectal cancers. Urothelial carcinoma of the upper urinary tract is quite rare and accounts for 5–10 % of all cases of this type of cancer. Tumors of the renal pelvis are 2 times more common than tumors of the ureter. A clinical case of a 69-year-old patient diagnosed with urothelial carcinoma of the left renal pelvis T2N0M1, stage IV and metastases into the bladder, right renal pelvis is presented. On 08.06.2023, the patient underwent transurethral resection of the bladder tumor, ureteric orifice, nephroureterectomy on the left, retroperitoneal lymphadenectomy. Between 07.2023 and 10.2023, the patient received 6 cycles of chemotherapy according to the following scheme: gemcitabine 1000 mg/m2 intravenously on the 1st and 8th days ++ carboplatin AUC 5 intravenously on the 1st day. Since 11.2023, the patient in receiving maintenance therapy with avelumab.
Metastasectomy in patients with multiple and oligometastases of renal cell carcinoma treated in general clinical practice
Authors: Semenov D. V. , Orlova R. V. , Shirokorad V. I. , Kostritskiy S. V. , Karlova N. A. 
Published: November 2024

Aim. To determine the impact of metastasectomy on overall survival in patients with metastatic renal cell carcinoma and to identify prognostic factors for this cytoreductive intervention.Materials and methods. We retrospectively analyzed the database of 226 patients who underwent metastasectomy at the Moscow City Oncological Hospital No. 62 and the City Clinical Oncological Dispensary (Saint Petersburg) between 2006 and 2022. Solitary and single metastases were detected in 103 (45.6 %), and multiple metastases – in 123 (54.5 %) patients. In patients with solitary and single metastases synchronous and metachronous metastases were detected in 20 (19.4 %) and 83 (80.6 %) patients, with multiple metastases – in 51 (41.5 %) and 72 (58.5 %) patients respectively. Complete metastasectomy was performed in 70 (68 %) patients with solitary, single metastases and in 36 (29.3 %) patients with multiple metastases. Patients with solitary and single metastases after complete metastasectomy did not receive systemic therapy until tumor progression. Before the start of drug therapy metastasectomy was performed in 63 (61.2 %) patients with solitary and single metastases, in case of multiple metastases in 17 (13.8 %) patients. Patients’ survival rates were evaluated using the Survival Analysis mathematical and statistical method with calculation of descriptive characteristics in the form of a life table and construction of Kaplan–Meier curves.Results. The univariate analysis in patients with multiple and oligometastases of renal cancer revealed that IMDC (International Metastatic RCC Database Consortium) prognosis, tumor differentiation degree per Fuhrman, ECOG (Eastern Cooperative Oncology Group) status, complete metastasectomy and metastasectomy after the start of systemic therapy had negative impact on survival rates. Multivariate analysis in patients with oligometastases of renal cancer revealed that IMDC prognosis, type of metastases, brain metastases, complete metastasectomy and metastasectomy after the start of systemic therapy had negative impact on survival rates, while in patients with multiple RCC metastases only complete metastasectomy and metastasectomy after the start of systemic therapy had negative impact on survival rates.Conclusion. Our data indicate that metastasectomy is an important component of multimodal treatment of metastatic renal cell carcinoma patients. To better define the indications for this cytoreductive surgery, further studies are needed to identify additional prognostic factors in metastatic renal cell carcinoma patients.