bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unity and diversity in working memory load: Evidence for the separability of the executive functions updating and inhibition using machine learning
Authors: Krumpe Tanja , Scharinger Christian , Rosenstiel Wolfgang , Gerjets Peter , Spüler Martin 
Published: August 2018

AbstractObjectiveAccording to current theoretical models of working memory (WM), executive functions (EFs) like updating, inhibition and shifting play an important role in WM functioning. The models state that EFs highly correlate with each other but also have some individual variance which makes them separable processes. Since this theory has mostly been substantiated with behavioral data like reaction time and the ability to execute a task correctly, the aim of this paper is to find evidence for diversity (unique properties) of the EFs updating and inhibition in neural correlates of EEG data by means of using brain-computer interface (BCI) methods as a research tool. To highlight the benefit of this approach we compare this new methodology to classical analysis approaches.MethodsAn existing study has been reinvestigated by applying neurophysiological analysis in combination with support vector machine (SVM) classification on recorded electroenzephalography (EEG) data to determine the separability and variety of the two EFs updating and inhibition on a single trial basis.ResultsThe SVM weights reveal a set of distinct features as well as a set of shared features for the two EFs updating and inhibition in the theta and the alpha band power.SignificanceIn this paper we find evidence that correlates for unity and diversity of EFs can be found in neurophysiological data. Machine learning approaches reveal shared but also distinct properties for the EFs. This study shows that using methods from brain-computer interface (BCI) research, like machine learning, as a tool for the validation of psychological models and theoretical constructs is a new approach that is highly versatile and could lead to many new insights.
Influence of temperature on the development, reproduction and regeneration in the flatworm model organismMacrostomum lignano
Authors: Wudarski Jakub , Ustyantsev Kirill , Glazenburg Lisa , Berezikov Eugene 
Published: August 2018

AbstractThe free-living marine flatwormMacrostomum lignanois a powerful model organism to study mechanisms of regeneration and stem cell regulation due to its convenient combination of biological and experimental properties, including the availability of transgenesis methods, which is unique among flatworm models. However, due to its relatively recent introduction in research, there are still many biological aspects of the animal that are not known. One of such questions is the influence of the culturing temperature onMacrostomumbiology. Here we systematically investigated how different culturing temperatures affect the development time, reproduction rate, regeneration, heat shock response, and gene knockdown efficiency by RNA interference inM. lignano.We used marker transgenic lines of the flatworm to accurately measure the regeneration endpoint and to establish the stress response threshold for temperature shock. We found that compared to the culturing temperature of 20°C commonly used forM. lignano, elevated temperatures of 25°C-30°C substantially speed-up the development and regeneration time and increase reproduction rate without detectable negative consequences for the animal, while temperatures above 30°C elicit a heat shock response.We show that altering the temperature conditions can be used to shorten the time required to establishM. lignanocultures, store important lines and optimize the microinjection procedures for transgenesis. Our findings will help to optimize the design of experiments inM. lignanoand thus facilitate future research in this model organism.
IDH1R132Hacts as a tumor suppressor in glioma via epigenetic upregulation of the DNA damage response
Authors: Núñez Felipe J. , Mendez Flor M. , Kadiyala Padma , Alghamri Mahmoud S. , Savelieff Masha G. , Koschmann Carl , Calinescu Anda-Alexandra , Kamran Neha , Patel Rohin , Carney Stephen , Guo Marissa Z. , Garcia-Fabiani Maria B. , Haase Santiago , Edwards Marta , Ljungman Mats , Qin Tingting , Sartor Maureen A. , Tagett Rebecca , Venneti Sriram , Brosnan-Cashman Jacqueline , Meeker Alan , Gorbunova Vera , Zhao Lili , Kremer Daniel M. , Zhang Li , Lyssiotis Costas A. , Jones Lindsey , Herting Cameron J. , Ross James L. , Hambardzumyan Dolores , Hervey-Jumper Shawn , Figueroa Maria E. , Lowenstein Pedro R. , Castro Maria G. 
Published: August 2018

One sentence summaryMutant IDH1 acts as a tumor suppressor when co-expressed together with TP53 and ATRX inactivating mutations in glioma, inducing genomic stability, DNA repair and resistance to genotoxic therapies.AbstractGlioma patients whose tumors carry a mutation in the Isocitrate Dehydrogenase 1 (IDH1R132H) gene are younger at the time of diagnosis and survive longer. The molecular glioma subtype which we modelled, harbors IDH1R132H, tumor protein 53 (TP53) and alpha-thalassemia/mental retardation syndrome X-linked (ATRX) loss. The impact of IDH1R132Hon genomic stability, DNA damage response (DDR) and DNA repair in this molecular glioma subtype is unknown. We discovered that IDH1R132Hexpression in the genetic context of ATRX and TP53 inactivation: (i) increases median survival (MS), (ii) enhances DDR activity via epigenetic upregulation of Ataxia-telangiectasia mutated (ATM) signaling, and (iii) elicits tumor radioresistance. Pharmacological inhibition of ATM or checkpoint kinase 1 and 2 (CHK1/2), two essential kinases in the DDR pathways, restored tumors’ radiosensitivity. Translation of these findings for mlDH1 glioma patients could significantly improve the therapeutic efficacy of radiotherapy, and thus have a major impact on patient survival.
Reactivation of time cell sequences in the hippocampus
Authors: Belchior Hindiael A. , Pavão Rodrigo , Furtunato Alan M.B. , Eichenbaum Howard , Tort Adriano B.L. 
Published: August 2018

AbstractThe temporal order of an experience is a fundamental property of episodic memories, yet the mechanism for the consolidation of temporal sequences in long-term memory is still unknown. A potential mechanism for memory consolidation depends on the reactivation of neuronal sequences in the hippocampus. Despite abundant evidence of sequence reactivation in the formation of spatial memory, the reactivation of hippocampal neuronal sequences carrying non-spatial information has been much less explored. In this work, we recorded the activity of time cell sequences while rats performed multiple 15-s treadmill runnings during the intertrial intervals of a spatial alternation memory task. We observed forward and reverse reactivations of time cell sequences often occurring during sharp-wave ripple events following reward consumption. Surprisingly, the reactivation events specifically engaged cells coding temporal information. The reactivation of time cell sequences may thus reflect the organization of temporal order required for episodic memory formation.
Reassembly classification selection method based on the Markov Chain
Authors: Ge Maogen , Hu Jing , Liu Mingzhou , Zhang Yuan 
Published: August 2018

Purpose
As the last link of product remanufacturing, reassembly process is of great importance in increasing the utilization of remanufactured parts as well as decreasing the production cost for remanufacturing enterprises. It is a common problem that a large amount of remanufactured part/reused part which past the dimension standard have been scrapped, which have increased the production cost of remanufacturing enterprises to a large extent. With the aim to improve the utilization of remanufacturing parts with qualified quality attributes but exceed dimension, the purpose of this paper is to put forward a reassembly classification selection method based on the Markov Chain.

Design/methodology/approach
To begin with, a classification standard of reassembly parts is proposed. With the thinking of traditional ABC analysis, a classification management method of reassembly parts for remanufactured engine is proposed. Then, a homogeneous Markov Chain of reassembly process is built after grading the matching dimension of reassembly parts with different variety. And the reassembly parts selection model is constructed based on the Markov Chain. Besides, the reassembly classification selection model and its flow chart are proposed by combining the researches above. Finally, the assembly process of remanufactured crankshaft is adopted as a representative example for illustrating the feasibility and the effectiveness of the method proposed.

Findings
The reassembly classification selection method based on the Markov Chain is an effective method in improving the utilization of remanufacturing parts/reused parts. The average utilization of remanufactured crankcase has increased from 35.7 to 80.1 per cent and the average utilization of reused crankcase has increased from 4.2 to 14 per cent as shown in the representative example.

Originality/value
The reassembly classification selection method based on the Markov Chain is of great importance in enhancing the economic benefit for remanufacturing enterprises by improving the utilization of remanufactured parts/reused parts.
Modelling and applications of conductive elements on textile materials
Authors: Pawlak Ryszard , Lebioda Marcin , Tomczyk Mariusz , Rymaszewski Jacek , Korzeniewska Ewa , Walczak Maria 
Published: August 2018

Purpose
Passive conducting elements are the important parts of textronic systems. This paper aims to study a possibility of creating well-conducting and durable elements in textile materials by combining two technologies – physical vapour deposition (PVD) and laser patterning.

Design/methodology/approach
Thin conducting metallic layers on common fabrics do not provide satisfactory resistance to bending and stretching; therefore, selected textile composite materials have been proposed as a substrate. The conducting elements were produced in two stage process – deposition of thin metallic layer on textile composite and creating conducting elements by laser patterning. Laser ablation process was optimized using modelling in Comsol Multiphysics package. Properties of conducting structures were investigated experimentally and by modelling.

Findings
This paper confirms the correctness of the choice of the textile composite as a substrate for conducting elements. The results have shown that combining PVD deposition of thin metallic layer and controlled laser ablation allow creating passive elements such as resistors, inductive coils and heaters. Computer simulations conducted in the Comsol Multihysics environment enabled to determine the temperature distribution around the heaters and to describe the dynamics of its changes. The obtained results allow to shorten time of the optimization process of structures with different geometry and assumed temperature distribution.

Originality/value
The novelty of this research can be summarized as following: choosing of textile composites as substrates for conductive elements instead of textiles used so far in textronics; creating conductive structures on textile composites using combined technologies, PVD and laser patterning, for the first time; modelling of laser ablation process of thin metallic layer; and optimization of properties of conducting elements by computer modelling.
Optimal selection of coaxial ring systems in environmental electrostatic shielding
Authors: Raicevic Nebojsa B. , Aleksic Slavoljub R. , Hederic Željko , Barukcic Marinko , Iatcheva Ilona 
Published: August 2018

Purpose
The purpose of this paper is to present a new calculation method for increasing the shielded volume in which the external electromagnetic field is maximally reduced. In a space shielded in the way mentioned in this paper, it is possible to introduce measurement instruments and increase the accuracy of results obtained with them, as well as reduce the risk of unwanted electrostatic field influence on living organisms.

Design/methodology/approach
A new numerical procedure for the optimization of the coaxial ring conductor system for electrostatic shielding is developed in the paper. The optimization of the functional that consists of electrostatic energy density and a system of equations derived from the equipotential character of the conductor system is used. The system of nonlinear equations is obtained and then numerically solved by minimizing this functional. The first presented optimization procedure is based on the analytical optimization method using the Lagrange coefficients and gradient of the objective function.

Findings
It is possible to design a large number of protective ring formations. Applying the differential evolution optimization method, an optimal arrangement can be obtained for any specific number of rings. The differential evolution optimization method, which belongs to the class of evolutionary algorithms, is used for solving this very complex optimization problem. In combination with the above-mentioned method, excellent results in the elimination of the external electric field have been obtained. Although a larger number of rings provides more efficient protection, this number is limited from the economic point of view. Therefore, it is necessary to achieve a compromise between the number of rings, the size of volume shielded and the quality of protection.

Research limitations/implications
There are few papers that address this problem, although the elimination of the influence of the external electromagnetic field has gained more importance lately. The presented method can be applied to increase the reliability of measured data, protection of the environment, in space research, etc. The main limiting factor for using a larger number of rings that provide better protection is the economical one.

Originality/value
The proposed method is suitable for the generalization of procedures, for the protection of the space where the external electric field needs to be reduced or eliminated.
Structural equation modelling for subcontracting practice: Malaysia chapter
Authors: Lew Yoke-Lian , Hassim Salihudin , Muniandy Ratnasamy , Hua Law Teik 
Published: August 2018

Purpose
Most of the previous studies conducted on the subject of subcontractors often focussed on a single phase of subcontracting practice; either on registration, selection of subcontractors or on monitoring of subcontractors without much integration to other different phases involved. Thus, on the basis of that reason, the purpose of this paper is to link the gap between different phases of subcontracting practice. This study also attempts to explore the relationships between the key criteria used by general contractors in selecting subcontractors before job awarding (CSSC) and the key criteria used for monitoring subcontractors during construction work (CMSC); which will then include an investigation of the effects these criteria have on project performance (PP).

Design/methodology/approach
The data obtained from a total of 162 G7 contractors in Malaysia were analysed. The interrelationships between the criteria and the effects of these criteria on PP were investigated simultaneously by employing a single model based on structural equation modelling (SEM) method.

Findings
The final model has discovered four major criteria that are often considered during the selection of subcontractors namely, “communication”, “relationship”, “general obligation” and “resource management” of a subcontractor. Meanwhile, the major criteria that are referred to in the monitoring of subcontractors are “workmanship”, “awareness of environment, health and safety” and “communication and relationship”. The four CSSC were found to be interrelated among themselves and affected CMSC during the construction stage. The research also revealed that the criteria used in monitoring subcontractor do affect the performance of a project. Thus, based on the result of this investigation, the monitoring of subcontractor is essential in discerning the performance level of a project.

Originality/value
An established SEM improves a subcontracting practice by creating platforms for CSSC, CMSC and PP to influence each other. With the gap between selection and monitoring subcontractors are filled, then the prediction of the subcontractors’ performance can be made possible.
Survival strategies of built environment organisations in a challenging economy
Authors: Aghimien Douglas Omoregie , Aghimien Emmanuel Imuetiyan , Fadiyimu Akinlolu Oyebobola , Adegbembo Taiwo Fadeke 
Published: August 2018

Purpose
The economic downturn in Nigeria calls for the need to appraise the survival strategies being adopted by organisations within the built environment, as it plays a major role in the development of every nation. The purpose of this paper is, therefore, to appraise the survival strategies of organisations within the built environment, with a view to showcasing these strategies to ensure continuous survival of organisations within the industry.

Design/methodology/approach
The study adopted a survey approach, and construction professionals across the six geo-political zones of the country were sampled using structured questionnaire. Data gathered were analysed using percentage, Kruskal–Wallis H-test and factor analysis.

Findings
The study revealed that organisation- and workforce management-related strategies are the most adopted survival strategies in the country, as they have the highest factor loading and accounts for about 37 per cent of the total extracted factors. This is followed by the adoption of strategies relating to organisation’s innovation, diversification, financial management and organisation’s networking, the combination of which accounts for 27.5 per cent of all extracted factors.

Research limitations/implications
Findings of this study imply that although organisations within the built environment see the need for effective management of their organisation and workforce in a bid to survive in the harsh economic situation of the country, more need to be done as regards the other identified survival strategies, as they can help ensure the survival of these organisations.

Originality/value
This study contributes to the body of knowledge as it showcases the survival strategies being adopted by the different organisations within the built environment in the challenging Nigerian economy, as against the usual common practice of studying specific organisations within the industry.
Supply chain resilience: a systematic literature review and typological framework
Authors: Kochan Cigdem Gonul , Nowicki David R. 
Published: August 2018

Purpose
The study of supply chain resilience (SCRES) continues to gain interest in the academic and practitioner communities. The purpose of this paper is to present a focused review of the SCRES literature by investigating supply chain (SC) capabilities, their relationship to SCRES outcomes and the underpinning theoretical mechanisms of this relationship.

Design/methodology/approach
The paper uses the systematic literature review approach to examine 383 articles published between 2000 and 2017, ultimately down selecting to the most relevant 228 peer-reviewed studies. Context-interventions-mechanisms-outcomes (CIMO) logic is applied to organize and synthesize these peer-reviewed studies. A typological framework is developed from the CIMO-based classification of the SCRES literature.

Findings
The findings of this study outline the gaps in the SCRES literature and present an agenda for future research.

Research limitations/implications
This paper presents an exploratory research; therefore, the typological model presented is just one of the possible perspectives.

Practical implications
The typology of SCRES literature can help practitioners to understand SCRES and to measure and assess the resilience of SCs.

Originality/value
The paper provides clear definitions of SCRES constructs, develops a typological framework to further understand SCRES and identifies SCRES measures and assessment techniques.
Integrating KPIs for improving efficiency in road transport
Authors: García-Arca Jesús , Prado-Prado J. Carlos , Fernández-González Arturo J. 
Published: August 2018

Purpose
The purpose of this paper is to propose and validate a framework for improving efficiency in road transport based on key performance indicators (KPIs) and personnel participation. The use of the “Overall Equipment Effectiveness” (OEE) indicator is widespread in factories. The framework adapts OEE to transport management.

Design/methodology/approach
Research was divided into two phases. The first phase included development of a participative framework, which was based on the authors’ experience and a literature review related to transport KPIs. The second phase involved the validation of the framework, adopting an “Action Research” approach by leading its implementation in a Spanish retailer.

Findings
Implementation of the framework has promoted more efficient transport in the company. The framework could be extrapolated to other companies, particularly, transport and parcel companies. By applying the “Action Research” approach it has been shown that researchers and practitioners can create knowledge by resolving problems that are of interest to both parties.

Research limitations/implications
The framework has been applied in one company and could achieve broader validation. Additionally, integrating only indicators of transport efficiency into the OEE proposal has meant that other perspectives, such as costs or the environment, have not been dealt with directly.

Originality/value
The framework is a new line of research applied to transport management. The academic and business contributions fall into three areas: transport management, organizational change and the methodology. There are few examples that illustrate “Action Research” adoption within the scope of supply chain management.
Oil film shape prediction of hydrostatic thrust bearing under the condition of high speed and heavy load
Authors: Yu Xiaodong , Zuo Xu , Liu Chao , Zheng Xuhang , Qu Hang , Yuan Tengfei 
Published: August 2018

Purpose
Hydrostatic thrust bearing is a key component of the vertical CNC machining equipment, and often results in friction failure under the working condition of high speed and heavy load. The lubricating oil film becomes thin or breaks because of high speed and heavy load and it affects the high precision and stable operation of the vertical CNC machining equipment; hence, it is an effective way of avoiding friction failure for achieving the oil film shape prediction

Design/methodology/approach
For the hydrostatic thrust bearing with double rectangular cavities, researchers solve the deformation of the friction pairs in hydrostatic bearing by using the computation of hydrodynamics, elasticity theory, finite element method and fluid-thermal-mechanical coupled method. The deformation includes heat deformation and elasticity deformation, the shape of gap oil film is got according to the deformation of the friction pairs in hydrostatic bearing, and gets the shape of gap oil film, and determines the influencing factors and laws of the oil film shape, and achieves the prediction of oil film shape, and ascertains the mechanism of friction failure. An experimental verification is carried out.

Findings
Results show that the deformation of the rotational workbench is upturned along its radial direction under the working condition of high speed and heavy load. However, the deformation of the base is downturned along its radial direction and the deformation law of the gap oil film along the radius direction is estimated; the outer diameter is close but the inner diameter is divergent wedge.

Originality/value
The conclusion can provide a theoretical basis for the oil film control of hydrostatic thrust bearing and improve the stability of vertical CNC machining equipment.