bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible Thermoelectric BiSbTe/Carbon Paper/BiSbTe Sandwiches for Bimode Temperature‐Pressure Sensors
Authors: Shu Min , He Zhengxi , Zhu Junjie , Ji Yuru , Zhang Xuefei , Zhang Chuanrui , Chen Mengran , Zong Peng‐an 
Published: November 2024

AbstractBimode temperature‐pressure sensors hold significant promise in personal health monitoring, wearables and robotic signal detection. Traditional bimode sensors typically combine two independent sensors, leading to fabrication complexity. This study develops a bimode temperature‐pressure sensor by using a facile electrodeposition method to create sandwiched BiSbTe/Carbon Paper/BiSbTe thin films and stacking them to a vertical structure. It demonstrates high sensitivity for temperature sensing, capable of detecting temperature difference as low as 1 K, and a rapid response time of 0.92 s due to a vertical structure. Utilizing its thermoelectric mechanism, the sensor achieves self‐powered sensing for finger touch and respiration states. Furthermore, its island‐like contact surface ensures high sensitivity with an extremely fast response time of 0.17 s, by rapidly changing contact resistance under pressure, allowing it to detect various human behaviors, including body movements and micro‐expressions. Beyond its sensing capabilities, the film excels in flexibility, electromagnetic interference shielding, and stability, presenting significant potential for integration into self‐powered electronic skin systems for health monitoring, wearables, artificial intelligence, and other electronic skin applications.
Nano‐Patterned CuO Nanowire Nanogap Hydrogen Gas Sensor with Voids
Authors: Zhao Muqing , Nitta Ryosuke , Izawa Seiichiro , Yamaura Jun‐ichi , Majima Yutaka 
Published: November 2024

AbstractHydrogen (H2) is increasingly employed in industrial applications, such as developing hydrogen fuel cells for vehicles and power plants. However, H2 explodes at a concentration limit of 4%, necessitating the development of ultrasensitive hydrogen sensors capable of early‐stage detection of hydrogen leaks. In this study, nano‐patterned polycrystalline cupric oxide (CuO) nanowire array nanogap gas sensors with voids are fabricated using electron‐beam lithography and ex situ oxidization by annealing, which could detect 5 ppb H2 and show response and recovery times of less than 10 s without a baseline shift. Combining a pre‐H2 annealing process in Ar/H2 for Cu nanowires and a low‐rate oxidation process enhances the crystallinity of CuO nanowires, facilitating the preparation of polycrystalline CuO nanowires with voids, which is a significantly practical approach for the improvements of gas sensing properties. Response and recovery times of <10 s can be obtained for a gap separation of ≈30 nm. These improvements are discussed based on a high electric field of ≈1.3 MV cm−1. The relationship between the normalized response and H2 concentration is discussed based on the power law. This paper presents highly reliable and fast H2 sensors without a baseline shift to meet the demands of the hydrogen industry.
Luminous Fish‐Inspired Hydrogels with Underwater Long‐Lived Room Temperature Phosphorescence
Authors: Chen Panyi , Qie Haofei , Yang Xipeng , Ma Song , Wang Zhengrui , Li Ningyan , Deng Yifan , Bian Fengling , Lü Shaoyu 
Published: November 2024

AbstractSome marine animals form long‐lived luminescence for predation, communication, camouflage, and anti‐predation. These marine animals demonstrate soft nature, sustainable glowing, and underwater emission, which are difficult to achieve in synthetic room temperature phosphorescence (RTP) materials. Inspired by these marine animals, here the study reports RTP hydrogels that show long‐lived phosphorescence (lifetime >500 ms and afterglow >10 s) in water. Exceptional underwater mechanical properties are simultaneously achieved, including tensile strength of 5.1 MPa, tensile strain of 452%, and toughness of 19.3 MJ m−3. The key to this achievement lies in the in situ phase separation microarchitecture formed between polyacrylamide (PAM) and its partial hydrolysates, which confines the motions of polymer chains and protects vulnerable triplet excitons from quenching of water. Such a strategy shows the merits of facile fabrication without laborious synthesis. In addition, these RTP hydrogels offer repeatable photoprinting and highly stability in water, providing a versatile platform for underwater applications of RTP materials, including information encryption and camouflage of marine animals.
3D Micro‐Nano Hierarchical Constructs Enabling Transmural Ingrowth of Adventitia Improves the “Fallout endothelialization” of Vascular Grafts
Authors: Fu Mingdi , Zhang Zheqian , Wang Yujiao , Zhang Wangqian , Yuan Pingping , Wang Xuqiao , Zhang Cun , Wu Wei 
Published: November 2024

AbstractImproving transmural ingrowth of adventitia is believed to promote luminal endothelialization during host remodeling of the vascular graft. However, fabricating vascular grafts with opening microstructures favoring cell ingrowth and tunable mechanical strength warranting clinical safety remains challenging. In this study, an ultrathin nanofibrous lumen stented with a highly porous tube is fabricated to acquire a harmonious balance between mechanical stability and the requisite openness for effective cell recruitment. In vitro examination reveals clinically feasible mechanical bridging of the rabbit carotid artery, such vascular graft with 3D micro‐nano hierarchical structures (3D‐MnHCs) enable fast and sufficient cell ingrowth, including transmural angiogenesis and muscular remodeling by myofibroblasts. Harnessing an integrated spatial transcriptomics approach and angiogenesis inhibition experiments, unprecedented insights revealing the positive roles of vascularized adventitia on “Fallout” endothelialization are provided. To conclude, 3D‐MnHCs offer a“concept of proof” for balancing adequate cell ingrowth and clinically applicable strength and degrading rates, therefore introducing a novel perspective for small caliber arterial regeneration.
Synthetic Nanocapsules with Tailored Surface Chemistry for Lung‐Specific Protein Delivery and Cancer Immunotherapy
Authors: Zheng Qizhen , Yao Rui , Liu Ji , Luo Tianli , Ma Tianyu , Wang Ming 
Published: November 2024

AbstractEfficient delivery of therapeutic proteins remains a major challenge in developing effective immunotherapies and treatments for genetic disorders due to the limited tissue targeting capability of native proteins. In this study, the design and synthesis of protein nanocapsules (NCs) that achieve lung‐specific delivery of therapeutic proteins are reported. These NCs are synthesized through a surface modification process that involves coating protein with functional monomers and cross‐linkers, followed by in situ polymerization to create a protective shell on the protein surface with tailored surface chemistry. This approach preserves protein integrity and significantly enhances delivery efficiency and tissue specificity. Notably, it is shown that protein@NC with guanidine‐rich surfaces exhibit exceptional lung‐targeting capabilities. This is likely attributed to the formation of a vitronectin‐rich protein corona, which facilitates receptor‐mediated endocytosis by lung cells. The platform effectively delivers various proteins, such as ovalbumin, to antigen‐presenting cells (APCs) in the lung, thereby enhancing antigen presentation and offering a promising strategy for cancer immunotherapy. These findings provide a significant advancement in tissue‐specific protein delivery and hold the potential for targeted cancer immunotherapy.
Construction of Somatostatin‐Based Multiphase “Core–Shell” Coacervates as Photodynamic Biomimetic Organelles
Authors: Sun Wenyu , Xiong Hongjie , Yin Jiajia , Yao Wenyan , Liu Xiaohui , Liu Liu , Wang Xuemei , Jiang Hui 
Published: November 2024

AbstractBiomimetic coacervates have recently attracted great interest in biomedical fields, especially for drug delivery and as protocells. However, these membraneless structures are easily coalesced and poorly targetable, limiting their real biomedical applications. Here multiphase “core–shell” coacervate (CSC) constructed by dsDNA and somatostatin (SST), a 14‐mer cyclopeptide is designed. The CSC shows enhanced tumor targetability through SST binding to SST receptors on the tumor cells' surface. G4 quadruplex‐hemin complex can be embedded in the CSC by interaction with SST, as demonstrated by molecular simulation and isothermal titration calorimetry. The G4‐hemin embedded CSC can further recruit photosensitizers such as tetracarboxyphenyl porphyrin to form the CSC‐GHT composite for photodynamic therapy (PDT). As photodynamic biomimetic organelles, CSC‐GHT can convert oxygen to singlet oxygen (catalyzed by the catalase‐mimetic activity of G4‐hemin), resulting in enhanced PDT effect, which allows the inhibition of cellular migration in vitro and tumor growth in vivo. Owing to high stability, targetability, and biosafety, the proposed CSC can recruit various cargos from small dyes to large biomacromolecules (up to 430 kDa), providing promising theranostic applications.
Lateral Phase Heterojunction for Perovskite Microoptoelectronics
Authors: Li Lei , Yan Haoming , Li Shunde , Xu Hongyu , Qu Duo , Hu An , Ma Li , Ji Yongqiang , Zhong Qixuan , Zhao Lichen , Xu Fan , Tu Yongguang , Song Tinglu , Wu Jiang , Li Menglin , Lu Changjun , Yang Xiaoyu , Zhong Haizheng , Gong Qihuang , Wang Xinqiang , Zhu Rui 
Published: November 2024

AbstractPerovskite heterojunction engineering is the prerequisite but still a deficiency in the fabrication of micro‐optoelectronic devices, where the present top‐down or bottom‐up techniques mainly focus on preparing the vertical heterojunction stacks. Perovskite lateral heterojunction structures generally rely on epitaxial growth, which cannot meet the demands of mass production of micro‐devices. Here, a contact diffusion lithography technique is proposed to demonstrate a perovskite lateral phase heterojunction (LPH) polycrystalline film by ion‐driven local phase transition. Under the guidance of thermodynamic simulations, methylamine contact and migration collectively promote in situ formation of α‐phase formamidine‐based perovskite patterns surrounded by δ‐phase polymorphs. Spontaneous type‐I heterojunction alignment between α‐ and δ‐phases establishes energy funnels in the LPH film to facilitate carrier utilization and radiative recombination. The wide‐bandgap δ‐phase also serves as the coplanar isolator to achieve local anti‐leakage for device integration. Based on the bright and stable LPH pattern layer, the near‐infrared microscale perovskite light‐emitting diode (micro‐PeLED) with impressive device performance is achieved by following conventional device fabrication protocol. The proposed LPH enriches the perovskite heterojunction family, creates a new optoelectronic processing platform, and advances its versatile applications in micro‐optoelectronics and photonics.
Substantially Enhanced Spin Polarization in Epitaxial CrTe2 Quantum Films
Authors: Zhang Xiaoqian , Lu Qiangsheng , Shen Zhen‐Xiong , Niu Wei , Liu Xiangrui , Lu Jiahua , Lin Wenting , Han Lulu , Weng Yakui , Shao Tianhao , Yan Pengfei , Ren Quan , Li Huayao , Chang Tay‐Rong , Singh David J. , He Lixin , He Liang , Liu Chang , Bian Guang , Miao Lin , Xu Yongbing 
Published: November 2024

Abstract2D van der Waals (vdW) magnets, which extend to the monolayer (ML) limit, are rapidly gaining prominence in logic applications for low‐power electronics. To improve the performance of spintronic devices, such as vdW magnetic tunnel junctions, a large effective spin polarization of valence electrons is highly desired. Despite its considerable significance, direct probe of spin polarization in these 2D magnets has not been extensively explored. Here, using 2D vdW ferromagnet of CrTe2 as a prototype, the spin degrees of freedom in the thin films are directly probed using Mott polarimetry. The electronic band of 50 ML CrTe2 thin film, spanning the Brillouin zone, exhibits pronounced spin‐splitting with polarization peaking at 7.9% along the out‐of‐plane direction. Surprisingly, atomic‐layer‐dependent spin‐resolved measurements show a significantly enhanced spin polarization in a 3 ML CrTe2 film, achieving 23.4% polarization even in the absence of an external magnetic field. The demonstrated correlation between spin polarization and film thickness highlights the pivotal influence of perpendicular magnetic anisotropy, interlayer interactions, and itinerant behavior on these properties, as corroborated by theoretical analysis. This groundbreaking experimental verification of intrinsic effective spin polarization in CrTe2 ultrathin films marks a significant advance in establishing 2D ferromagnetic atomic layers as a promising platform for innovative vdW‐based spintronic devices.
Boosting the Structural and Electrochemical Stability of Chloride‐Ion‐Conducting Perovskite Solid Electrolytes by Alkali Ion Doping
Authors: Xia Tianchen , Li Qiang , Xue Zhiyang , Miao Yingchun , Shen Xiaodong , Zhao Xiangyu 
Published: November 2024

AbstractThe use of chloride‐based solid electrolytes derived from Lewis acid‒base reactions enables the construction of various new rechargeable batteries, such as chloride ion batteries (CIBs). However, a critical problem with these electrolytes is their poor stability under low‐temperature, moist, or electrochemical conditions, which can lead to deterioration of the phase structure and a loss of ion conduction. Herein, the robust cubic structure of tin‐based perovskite chloride—a chloride ion conductor—is achieved by alkali ion doping at the tin site via direct mechanical milling. The as‐prepared cubic CsSn0.925Na0.075Cl2.925 (CSNC) electrolyte exhibits outstanding structural stability over a broad temperature range of 213−473 K or under a high relative humidity of up to 90%, at which the typical chloride electrolytes previously reported deteriorate because of moisture. Importantly, mild annealing can modify the microstructure of the CSNC, resulting in a two fold increase in ionic conductivity and an increase in electrochemical stability, which is superior to those of other chloride electrolytes reported in previous studies. The effective chloride‐ion transfer and wide electrochemical window of the CSNC are further demonstrated in different solid‐state CIBs.
Catalytic Biomaterials‐Activated In Situ Chemical Reactions: Strategic Modulation and Enhanced Disease Treatment
Authors: Wang Huijing , He Wenjin , Liao Jing , Wang Shuangshuang , Dai Xinyue , Yu Meihua , Xie Yujie , Chen Yu 
Published: November 2024

AbstractChemical reactions underpin biological processes, and imbalances in critical biochemical pathways within organisms can lead to the onset of severe diseases. Within this context, the emerging field of “Nanocatalytic Medicine” leverages nanomaterials as catalysts to modulate fundamental chemical reactions specific to the microenvironments of diseases. This approach is designed to facilitate the targeted synthesis and localized accumulation of therapeutic agents, thus enhancing treatment efficacy and precision while simultaneously reducing systemic side effects. The effectiveness of these nanocatalytic strategies critically hinges on a profound understanding of chemical kinetics and the intricate interplay of reactions within particular pathological microenvironments to ensure targeted and effective catalytic actions. This review methodically explores in situ catalytic reactions and their associated biomaterials, emphasizing regulatory strategies that control therapeutic responses. Furthermore, the discussion encapsulates the crucial elements‐reactants, catalysts, and reaction conditions/environments‐necessary for optimizing the thermodynamics and kinetics of these reactions, while rigorously addressing both the biochemical and biophysical dimensions of the disease microenvironments to enhance therapeutic outcomes. It seeks to clarify the mechanisms underpinning catalytic biomaterials and evaluate their potential to revolutionize treatment strategies across various pathological conditions.
Biomimetic Chlorosomes: Oxygen‐Independent Photocatalytic Nanoreactors for Efficient Combination Photoimmunotherapy
Authors: Chen Fangman , Huang Hanyao , Zhang Fan , Wang Ran , Wang Lei , Chang Zhimin , Cao Lei , Zhang Wensheng , Li Li , Chen Meiwan , Shao Dan , Yang Chao , Dong Wen‐fei , Sun Wen 
Published: November 2024

AbstractPhotocatalytic therapy for hypoxic tumors often suffers from inefficiencies due to its dependence on oxygen and the risk of uncontrolled activation. Inspired by the oxygen‐independent and precisely regulated photocatalytic functions of natural light‐harvesting chlorosomes, chlorosome‐mimetic nanoreactors, termed Ru‐Chlos, are engineered by confining the aggregation of photosensitive ruthenium‐polypyridyl‐silane monomers. These Ru‐Chlos exhibit markedly enhanced photocatalytic performance compared to their monomeric counterparts under acidic conditions, while notably bypassing the consumption of oxygen or hydrogen peroxide. The photocatalytic activity of Ru‐Chlos is finely tunable through light‐responsive disassembly of the Ru‐bridged matrix, with tunability governed by pre‐irradiation duration. Utilization of Ru‐Chlos loading prodrug [2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid)] (ABTS) for phototherapy facilitates the generation of toxic radicals (oxABTS) and the photocatalytic conversion of endogenous NADH to NAD+, inducing oxidative stress in hypoxic cancer cells. Simultaneously, the light‐responsive degradation of Ru‐Chlos produces Ru‐based toxins that further contribute to the therapeutic effect. This dual‐action mechanism elicits potent immunogenic cell death effects and significantly enhances antitumor efficacy with the aid of a PD‐l blockade. These biomimetic chlorosomes highlight their potential to advance oxygen‐independent photocatalytic nanoreactors with controlled activity for novel cancer photoimmunotherapy strategies.
Pulmonary Flora‐Derived Lipopolysaccharide Mediates Lung‐Brain Axis through Activating Microglia Involved in Polystyrene Microplastic‐Induced Cognitive Dysfunction
Authors: Kang Huiwen , Huang Danyang , Zhang Wei , Wang JingYu , Liu Ziyan , Wang Ziyan , Jiang Guangyu , Gao Ai 
Published: November 2024

AbstractMicroplastics (MPs) have been detected in the atmospheric and the human respiratory system, indicating that the respiratory tract is a significant exposure route for MPs. However, the effect of inhaled MPs on cognitive function has not been adequately studied. Here, a C57BL/6 J mouse model of inhalation exposure to polystyrene MPs (PS‐MPs, 5 µm, 60 d) is established by intratracheal instillation. Interestingly, in vivo fluorescence imaging and transmission electron microscopy reveal that PS‐MPs do not accumulate in the brain. However, behavioral experiments shows that cognitive function of mice is impaired, accompanied by histopathological damage of lung and brain tissue. Transcriptomic studies in hippocampal and lung tissue have demonstrated key neuroplasticity factors as well as cognitive deficits linked to lung injury, respectively. Mechanistically, the lung‐brain axis plays a central role in PS‐MPs‐induced neurological damage, as demonstrated by pulmonary flora transplantation, lipopolysaccharide (LPS) intervention, and cell co‐culture experiments. Together, inhalation of PS‐MPs reduces cognitive function by altering the composition of pulmonary flora to produce more LPS and promoting M1 polarization of microglia, which provides new insights into the mechanism of nerve damage caused by inhaled MPs and also sheds new light on the prevention of neurotoxicity of environmental pollutants.
Thiocoumarin‐based Au(I) Complexes and Au(0) Systems over TiO2 as Hybrid Photocatalysts for Hydrogen Generation under UV–Vis Light
Authors: Agrelo‐Lestón Asier , Llorca Jordi , Martínez Elizabeth , Angurell Inmaculada , Rodríguez Laura , Soler Lluís 
Published: November 2024

AbstractThis work focuses on the photocatalytic production of hydrogen from the photodehydrogenation of ethanol using several gold(I) complexes and gold(0) systems over titanium dioxide (P90 TiO2) as hybrid photocatalysts. The photocatalytic systems are composed of at least one coumarin‐based ligand, which can enhance the photocatalytic activity by its photon‐absorbing capacity due to its chromophore properties. The photocatalytic behavior for hydrogen generation of the studied samples is compared under UV–vis light setting the total gold‐based co‐catalyst loading at 1 wt% onto the TiO2 photocatalysts and when the gold content is maintained at 0.25 wt%. The incorporation of gold co‐catalysts results in an enhancement of hydrogen production up to 2.7 times compared to a conventional Au/TiO2 reference sample. The results show an increase in the total hydrogen production under UV–vis light due to the combined presence of coumarin chromophore, gold‐based co‐catalysts, and gold plasmonic nanoparticles. A deep characterization of the samples from each group is performed by UV–vis spectroscopy, XPS, HRTEM, and HAADF‐STEM, observing the presence of plasmonic gold nanoparticles for sample “AuL1NPs” and the reduction of the gold present in sample “AuL1a,” which explains the highest observed hydrogen production rates of this study.
Drying of Soft Colloidal Films
Authors: Kuk Keumkyung , Ringling Julian , Gräff Kevin , Hänsch Sebastian , Carrasco‐Fadanelli Virginia , Rudov Andrey A. , Potemkin Igor I. , von Klitzing Regine , Buttinoni Ivo , Karg Matthias 
Published: November 2024

AbstractThin films made of deformable micro‐ and nano‐units, such as biological membranes, polymer interfaces, and particle‐laden liquid surfaces, exhibit a complex behavior during drying, with consequences for various applications like wound healing, coating technologies, and additive manufacturing. Studying the drying dynamics and structural changes of soft colloidal films thus holds the potential to yield valuable insights to achieve improvements for applications. In this study, interfacial monolayers of core‐shell (CS) microgels with varying degrees of softness are employed as model systems and to investigate their drying behavior on differently modified solid substrates (hydrophobic vs hydrophilic). By leveraging video microscopy, particle tracking, and thin film interference, this study shed light on the interplay between microgel adhesion to solid surfaces and the immersion capillary forces that arise in the thin liquid film. It is discovered that a dried replica of the interfacial microstructure can be more accurately achieved on a hydrophobic substrate relative to a hydrophilic one, particularly when employing softer colloids as opposed to harder counterparts. These observations are qualitatively supported by experiments with a thin film pressure balance which allows mimicking and controlling the drying process and by computer simulations with coarse‐grained models.