bluuebunny/crossref_metadata_2025_split huggingface dataset:
An indissoluble knot: An unexpected troubleshooting during Micra implantation
Authors: Cipolletta Laura , Volpato Giovanni , Biffi Mauro , Capucci Alessandro 
Published: December 2018

AbstractMicra is a transcatheter leadless pacing system delivered percutaneously through femoral vein access into the right ventricle. We are going to describe an initially standard procedure, with an unexpected troubleshooting at the end: the impossibility to release the device and retract the delivery due to a knot in the tether.
Vagus nerve stimulation reduces ventricular arrhythmias and increases ventricular electrical stability
Authors: Nasi‐Er Buajieer‐guli , Wenhui Zhang , HuaXin Sun , Xianhui Zhou , Yaodong Li , Yanmei Lu , Hongli Wang , TuEr‐Hong ZuKe‐la , Qina Zhou , BaoPeng Tang 
Published: December 2018

AbstractBackgroundTranscutaneous stimulation of the auricular branch of the vagus nerve (AB‐VNS) is a potentially noninvasive, inexpensive, and safe approach for vagus nerve stimulation that suppresses the induction and duration of atrial fibrillation and reduces sympathetic nerve outflow in healthy humans. Researchers have not determined whether AB‐VNS affects ventricular arrhythmias.ObjectiveTo evaluate the antiarrhythmic effects of noninvasive AB‐VNS on ventricular arrhythmias induced by myocardial infarction (MI).Methods and ResultsTwelve beagle dogs were randomly divided into the following two groups: a AB‐VNS group (coronary artery occlusion and noninvasive AB‐VNS) and a control group (coronary artery occlusion but without AB‐VNS). We examined spontaneous ventricular arrhythmias, ventricular electrophysiological properties, and cardiac function in conscious dogs. Morphology, fibrosis, and ultrastructures were also assessed. AB‐VNS significantly reduced the occurrence of spontaneous ventricular arrhythmias, including isolated premature ventricular complexes, ventricular couplets, ventricular bigeminy, ventricular trigeminy, and ventricular tachycardia. AB‐VNS effectively increased ventricular electrical stability, including significantly prolonged ventricular effective refractory periods, decreased the dispersion of effective refractory period, enhanced the ventricular fibrillation threshold, and decreased the maximum slope of the monophasic action potential duration restitution curve. AB‐VNS treatments alleviate ventricular interstitial fibrosis after MI. However, cardiac function was not improved, and MI‐induced ultrastructural changes in the myocardium were not reversed by 4 weeks of AB‐VNS. In addition, AB‐VNS for 4 weeks resulted in mild mitochondrial swelling within the neuronal axons of the auricular vagus fiber.ConclusionsNoninvasive AB‐VNS reduces the occurrence of spontaneous ventricular arrhythmias in conscious dogs with MI. AB‐VNS increases ventricular electrical stability and alleviates ventricular interstitial fibrosis induced by MI.
Phytochrome F plays critical roles in potato photoperiodic tuberization
Authors: Zhou Tingting , Song Botao , Liu Tengfei , Shen Yunlong , Dong Liepeng , Jing Shenglin , Xie Conghua , Liu Jun 
Published: December 2018

SummaryThe transition to tuberization contributes greatly to the adaptability of potato to a wide range of environments. Phytochromes are important light receptors for the growth and development of plants, but the detailed functions of phytochromes remain unclear in potato. In this study, we first confirmed that phytochrome F (StPHYF) played essential roles in photoperiodic tuberization in potato. By suppressing the StPHYF gene, the strict short‐day potato genotype exhibited normal tuber formation under long‐day (LD) conditions, together with the degradation of the CONSTANTS protein StCOL1 and modulation of two FLOWERING LOCUS T (FT) paralogs, as demonstrated by the repression of StSP5G and by the activation of StSP6A during the light period. The function of StPHYF was further confirmed through grafting the scion of StPHYF‐silenced lines, which induced the tuberization of untransformed stock under LDs, suggesting that StPHYF was involved in the production of mobile signals for tuberization in potato. We also identified that StPHYF exhibited substantial interaction with StPHYB both in vitro and in vivo. Therefore, our results indicate that StPHYF plays a role in potato photoperiodic tuberization, possibly by forming a heterodimer with StPHYB.
Brucellosis knowledge and preventive practices among herders in Western Mongolia
Authors: Bat‐Erdene Delgermaa , Chuang Ying‐Chih , Chuang Kun‐Yang 
Published: December 2018

AbstractLack of knowledge regarding brucellosis may lead to highly risky practices. Among herders in Mongolia, little research was conducted assessing the extent of knowledge related to brucellosis, the type of preventive behaviours that were practiced, and the relationship between knowledge and behaviour regarding brucellosis. A cross‐sectional study was conducted in two provinces of Mongolia where herders were randomly selected to participate in the study. Face‐to‐face interviews were conducted using a structured questionnaire. In total, 485 herders participated in the study. The results indicated that brucellosis preventive practices were significantly associated with sex, location, use of veterinary services, exposure to TV programs and knowledge of brucellosis. Regional disparities in knowledge and behaviour were observed in this research. Herders were more likely to engage in preventive practices if they had a higher level of knowledge of brucellosis. Findings from this research indicated that the effectiveness of incorporating health education through TV programs, as well as the importance of ensuring access to veterinary services in brucellosis prevention.
A new surface gliding species of Chironomidae: An independent invasion of marine environments and its evolutionary implications
Authors: Qi Xin , Lin Xiao‐Long , Ekrem Torbjørn , Beutel Rolf Georg , Song Chao , Orlov Igor , Chen Chun‐Tang , Wang Xin‐Hua 
Published: December 2018

AbstractInsects have invaded marine habitats only rarely and secondarily. Recently, we discovered a flightless dipteran species skating rapidly on the surface of seawater ponds at the Pacific coast of eastern China. Morphological analyses initially suggested an isolated position of the non‐biting midge, suggesting the erection of a new genus within Chironomini (Diptera: Chironomidae). However, an analysis of molecular data revealed that the marine species is in fact nested within the species‐rich genus Dicrotendipes. The apparent conflict between molecular and morphological data can be easily explained. It is likely that the new species has evolved a series of autapomorphic adaptations. These traits clearly distinguish the taxon from other species of the genus but do not justify the erection of a new supraspecific taxon, which would render Dicrotendipes paraphyletic. The switch to marine environments was likely a trigger for various morphological modifications resulting from increased selective pressure. Molecular data suggest that the potential speciation event occurred around 19–29 Ma, linked with a migration from freshwater to seawater ponds along the Pacific Ocean. Considering the results of our analysis, we place the flightless marine skater in the genus Dicrotendipes. All life stages of Dicrotendipes sinicus Qi & Lin sp. n. are described and illustrated, associated with larvae obtained by rearing or confirmed through association with DNA barcodes. The biology and ecology of the species are outlined based on collection data and in situ observations. Evolutionary patterns linked with repeated invasions of marine habitats are discussed.
Rates and characteristics of postcolonoscopy colorectal cancer in the Swedish IBD population: what are the differences from a non-IBD population?
Authors: Stjärngrim Jessica , Ekbom Anders , Hammar Ulf , Hultcrantz Rolf , Forsberg Anna M 
Published: December 2018

ObjectiveThe rate of postcolonoscopy colorectal cancer (PCCRC) is considered a key quality indicator of colonoscopy; little is known about PCCRC in IBD.DesignA population-based cohort study of colonoscopies in Sweden from 2001 to 2010 was conducted. Individuals with a colorectal cancer (CRC) detected within 36 months after a colonoscopy were identified and stratified on UC, Crohn’s disease (CD) or non-IBD. The CRCs were classified as detected CRCs (dCRC) (0–6 months) or as PCCRCs (6–36 months). PCCRC rates were calculated by the number of false negative/(the number of true positive+the number of false negative) colonoscopies. Poisson regression analysis was employed to examine the association between PCCRC and IBD (CD and UC) diagnosis, age, gender, location, time period and comorbidities.ResultsWe identified 348 232 colonoscopies in 270 918 individuals. Of these, 27 123 were performed on 14 597 individuals with CD, and 51 572 were performed on 26 513 individuals with UC. There were 13 317 CRCs in the non-IBD group, 133 in the CD group and 281 in the UC group. The PCCRC rate in the CD group was 28.3% and 41.0% in the UC group. The RR for a PCCRC was 3.82 (95% CI 2.94 to 4.96) in CD and 5.89 (95% CI 5.10 to 6.80) in UC, compared with non-IBD. The highest risk was observed among rectal cancer location in CD and in younger individuals with UC.ConclusionThe high rates of PCCRC in young patients with UC and for rectal cancer location in CD might affect future performance of IBD surveillance.
Role of TLR4 in the gut-brain axis in Parkinson’s disease: a translational study from men to mice
Authors: Perez-Pardo Paula , Dodiya Hemraj B , Engen Phillip A , Forsyth Christopher B , Huschens Andrea M , Shaikh Maliha , Voigt Robin M , Naqib Ankur , Green Stefan J , Kordower Jeffrey H , Shannon Kathleen M , Garssen Johan , Kraneveld Aletta D , Keshavarzian Ali 
Published: December 2018

ObjectiveRecent evidence suggesting an important role of gut-derived inflammation in brain disorders has opened up new directions to explore the possible role of the gut-brain axis in neurodegenerative diseases. Given the prominence of dysbiosis and colonic dysfunction in patients with Parkinson’s disease (PD), we propose that toll-like receptor 4 (TLR4)-mediated intestinal dysfunction could contribute to intestinal and central inflammation in PD-related neurodegeneration.DesignTo test this hypothesis we performed studies in both human tissue and a murine model of PD. Inflammation, immune activation and microbiota composition were measured in colonic samples from subjects with PD and healthy controls subjects and rotenone or vehicle-treated mice. To further assess the role of the TLR4 signalling in PD-induced neuroinflammation, we used TLR4-knockout (KO) mice in conjunction with oral rotenone administration to model PD.ResultsPatients with PD have intestinal barrier disruption, enhanced markers of microbial translocation and higher pro-inflammatory gene profiles in the colonic biopsy samples compared with controls. In this regard, we found increased expression of the bacterial endotoxin-specific ligand TLR4, CD3+ T cells, cytokine expression in colonic biopsies, dysbiosis characterised by a decrease abundance of SCFA-producing colonic bacteria in subjects with PD. Rotenone treatment in TLR4-KO mice revealed less intestinal inflammation, intestinal and motor dysfunction, neuroinflammation and neurodegeneration, relative to rotenone-treated wild-type animals despite the presence of dysbiotic microbiota in TLR4-KO mice.ConclusionTaken together, these studies suggest that TLR4-mediated inflammation plays an important role in intestinal and/or brain inflammation, which may be one of the key factors leading to neurodegeneration in PD.
Yield of peripheral sodium channels gene screening in pure small fibre neuropathy
Authors: Eijkenboom Ivo , Sopacua Maurice , Hoeijmakers Janneke G J , de Greef Bianca T A , Lindsey Patrick , Almomani Rowida , Marchi Margherita , Vanoevelen Jo , Smeets Hubertus J M , Waxman Stephen G , Lauria Giuseppe , Merkies Ingemar S J , Faber Catharina G , Gerrits Monique M 
Published: December 2018

BackgroundNeuropathic pain is common in peripheral neuropathy. Recent genetic studies have linked pathogenic voltage-gated sodium channel (VGSC) variants to human pain disorders. Our aims are to determine the frequency ofSCN9A,SCN10AandSCN11Avariants in patients with pure small fibre neuropathy (SFN), analyse their clinical features and provide a rationale for genetic screening.MethodsBetween September 2009 and January 2017, 1139 patients diagnosed with pure SFN at our reference centre were screened forSCN9A,SCN10AandSCN11Avariants. Pathogenicity of variants was classified according to established guidelines of the Association for Clinical Genetic Science and frequencies were determined. Patients with SFN were grouped according to the VGSC variants detected, and clinical features were compared.ResultsAmong 1139 patients with SFN, 132 (11.6%) patients harboured 73 different (potentially) pathogenic VGSC variants, of which 50 were novel and 22 were found in ≥ 1 patient. The frequency of (potentially) pathogenic variants was 5.1% (n=58/1139) forSCN9A,3.7% (n=42/1139) forSCN10Aand 2.9% (n=33/1139) forSCN11A. Only erythromelalgia-like symptoms and warmth-induced pain were significantly more common in patients harbouring VGSC variants.Conclusion(Potentially) pathogenic VGSC variants are present in 11.6% of patients with pure SFN. Therefore, genetic screening ofSCN9A, SCN10AandSCN11Ashould be considered in patients with pure SFN, independently of clinical features or underlying conditions.
Ḥayyūdj, Revolução Gramatical do Hebraico e o سَاكِت لَتّن סַאכִּן לַיִّן Sākin Layyin “Repouso Frágil”
Authors: Faldini Fabio 
Published: December 2018

A noção de que o verbo hebraico é triliteral e formado pela intercalação de dois morfemas ‒ um consonantal, que lhe outorga o sentido abstrato, e outro transfixo, formado por vogais e consoantes que lhe definem o sentido concreto e materializado ‒ remonta à segunda metade do século X, ao sábio andaluz Abū Zakariyaʾ Yaḥya Ibn Dāwūd, de Fez (Marrocos), mais conhecido como Ḥayyūdj. Neste artigo, apresenta-se quem foi este grande sábio, as suas obras e de forma sucinta o conceito gramatical que sustenta a teoria da triliteralidade do verbo hebraico por ele desenvolvida: o سَاكِت لَتّن סַאכִּן לַיִّן sākin layyin “quiescente frágil”.
Prosopis juliflora pods mash for biofuel energy production: Implication for managing invasive species through utilization
Authors: Haile Mebrahtu , Hishe Hadgu , Gebremedhin Desta 
Published: December 2018

Fuels obtained from renewable resources have merited a lot of enthusiasm amid the previous decades mostly because of worries about fossil fuel depletion and climate change. The aim of this study was to investigate the potential of Prosopis juliflora pods mash for bio-ethanol production and its hydrolysis solid waste for solid fuel. Parameters such as acid concentration (0.5 - 3 molar), hydrolysis times (5-30 min), fermentation times (6-72h), fermentation temperature (25 OC - 40 OC) and pH (4-8) on bio-ethanol production using Saccharomyces cerevisiae yeast were evaluated. Results show that the content of sugar increases as the acid concentration (H2SO4) increased up to 1 molar and decreases beyond 1 molar. A maximum sugar content of 96.13 %v/v was obtained at 1 molar of H2SO4 concentration. The optimum conditions for bio-ethanol production were found at 1 molar of H2SO4 concentration (4.2 %v/v), 48 h fermentation time (5.1%v/v), 20 min hydrolysis time (5.57 %v/v), 30 OC fermentation temperature (5.57 %v/v) and pH 5 (6.01 %v/v). Under these optimum conditions, the maximum yield of bio-ethanol (6.01%v/v) was obtained. Furthermore, the solid waste remaining after bio-ethanol production was evaluated for solid fuel application (18.22 MJ/kg). Hence, the results show that Prosopis juliflora pods mash has the potential to produce bio-ethanol. The preliminary analysis of solid waste after hydrolysis suggests the possibility to use it as a solid fuel, implying its potential for alleviating major disposal problems.Article History: Received March 24th 2018 ; Received in revised form September 15th 2018; Accepted October 1st 2018; Available onlineHow to Cite This Article: Haile, M., Hishe, H. and Gebremedhin, D. (2018) Prosopis juliflora Pods Mash for Biofuel Energy Production: Implication for Managing Invasive Species through Utilization. International Journal of Renewable Energy Development, 7(3), 205-212.https://doi.org/10.14710/ijred.7.3.205-212
Terrorism and Firm Performance: Empirical Evidence from Pakistan
Authors: Mazhar Ummad 
Published: December 2018

Abstract
A secure business environment for private enterprises is desired by all states and is endorsed as a part of United Nation’s sustainable development goals. However, the risk exposure of private enterprises against terrorism, particularly in developing countries, is not adequately studied. Using Enterprise Surveys (ES) data for more than 2000 firms located across the four provinces of Pakistan, this paper studies the link between the risk of terrorism and firm performance. It finds, after controlling for various firm specific performance determinants as well as provincial and sector specific heterogeneities, that terrorism has a significant negative effect on firms’ performance which is independent of firm size. This effect is robust against different specifications and estimation methods including instrumental variables strategy. Beyond much explored aggregate consequences, terrorism has direct consequences for production processes at micro level.
Impurity Distribution after Solidification of Hypereutectic Al-Si Melts and Eutectic Al-Si Melt
Authors: Li Yanlei , Chen Jian , Dai Songyuan 
Published: December 2018

Abstract
Hypereutectic Al-Si melts and eutectic Al-Si melt were solidified to study boron and phosphorus distributions in primary silicon phase, eutectic silicon phase and eutectic aluminum phase during Al-Si solvent refining. The boron and phosphorus contents in the primary silicon phase and the eutectic silicon phase were determined by ICP-OES, and the boron and phosphorus contents in the eutectic aluminum phase were calculated by the principle of mass conservation. The primary silicon phase has lowest boron and phosphorus contents, while the eutectic aluminum phase has highest boron and phosphorus contents.
Applied cognitive linguistics and foreign language learning. Introduction to the special issue
Authors: Hijazo-Gascón Alberto , Llopis-García Reyes 
Published: December 2018

AbstractThis introduction provides an overview of the intersection between Applied Cognitive Linguistics and Second/Foreign Language Learning. First, the relevance of Cognitive Linguistics (CL) for Applied Linguistics in general is discussed. The second section explains the main principles of CL and how each relates to the acquisition of second languages: (i) language and human cognition, (ii) language as symbolic, (iii) language as motivated; and (iv) language as usage-based. Section three offers a review of previous literature on CL and L2s that are different from English, as it is one the main aims of this Special Issue to provide state-of-the-art research and scholarship to enhance the bigger picture of the field of Second Language Acquisition beyond English as the target language. Spanish as L2/FL in Applied Cognitive Linguistics is the focus of the next section, which leads to a brief overview of the papers included in the Issue, featuring Spanish as the L2 with L1s such as English, French, German and Italian. Polysemy, Motion Events Typology, Cognitive Grammar and Construction Grammar are the Cognitive Linguistics areas addressed in the contributions here presented.
Nonlinear optical properties and applications of 2D materials: theoretical and experimental aspects
Authors: You J.W. , Bongu S.R. , Bao Q. , Panoiu N.C. 
Published: December 2018

Abstract
In this review, we survey the recent advances in nonlinear optics and the applications of two-dimensional (2D) materials. We briefly cover the key developments pertaining to research in the nonlinear optics of graphene, the quintessential 2D material. Subsequently, we discuss the linear and nonlinear optical properties of several other 2D layered materials, including transition metal chalcogenides, black phosphorus, hexagonal boron nitride, perovskites, and topological insulators, as well as the recent progress in hybrid nanostructures containing 2D materials, such as composites with dyes, plasmonic particles, 2D crystals, and silicon integrated structures. Finally, we highlight a few representative current applications of 2D materials to photonic and optoelectronic devices.
The crystal structure of poly[triaqua-bis(μ3-2,5-dihydroxyterephthalato-κ4
O,O′:O′′:O′′′)-(μ4-oxalato-κ4
O,O′:O′′,O′′′)cerium(III)], C9H10CeO11
Authors: Xue Li , Han-Yang Sun , Shuang Han , Jia-Jun Wang , Hao-Yan Mao , Chun-Ling Liu , Shou-Cai Zhang , Chuan-Bi Li 
Published: December 2018

Abstract
C9H10CeO11, triclinic, P1̄ (no. 2), a = 6.9100(14) Å, b = 9.1700(18) Å, c = 10.720(2) Å, α = 69.53(3)°, β = 83.56(3)°, γ = 87.01(3)°, V = 632.3(2) Å3, Z = 2, R
gt(F) = 0.0265, wR
ref(F
2) = 0.0487, T = 298(2) K.
Crystal structure of 5-(4-fluorophenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione, C9H8FN3S
Authors: Aouad Mohamed Reda , Messali Mouslim , Alharbi Khalid , Rezki Nadjet , Zarrouk Abdelkader , Warad Ismail 
Published: December 2018

Abstract
C9H8FN3S, monoclinic, P21/c, a = 15.8636(6) Å, b = 7.6641(3) Å, c = 16.4472(7) Å, β = 106.016(2)°, V = 1922.04(13) Å3, Z = 4, R
gt(F) = 0.0348, wR
ref(F
2) = 0.1001, T = 296(2) K.
Mathematical model on distributed denial of service attack through Internet of things in a network
Authors: Mishra Bimal Kumar , Keshri Ajit Kumar , Mallick Dheeresh Kumar , Mishra Binay Kumar 
Published: December 2018

Abstract
Internet of Things (IoT) opens up the possibility of agglomerations of different types of devices, Internet and human elements to provide extreme interconnectivity among them towards achieving a completely connected world of things. The mainstream adaptation of IoT technology and its widespread use has also opened up a whole new platform for cyber perpetrators mostly used for distributed denial of service (DDoS) attacks. In this paper, under the influence of internal and external nodes, a two - fold epidemic model is developed where attack on IoT devices is first achieved and then IoT based distributed attack of malicious objects on targeted resources in a network has been established. This model is mainly based on Mirai botnet made of IoT devices which came into the limelight with three major DDoS attacks in 2016. The model is analyzed at equilibrium points to find the conditions for their local and global stability. Impact of external nodes on the over-all model is critically analyzed. Numerical simulations are performed to validate the vitality of the model developed.