bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regression analysis for detecting epileptic seizure with different feature extracting strategies
Authors: Hussain Lal , Saeed Sharjil , Idris Adnan , Awan Imtiaz Ahmed , Shah Saeed Arif , Majid Abdul , Ahmed Bilal , Chaudhary Quratul-Ain 
Published: May 2019

Abstract
Due to the excitability of neurons in the brain, a neurological disorder is produced known as epilepsy. The brain activity of patients suffering from epilepsy is monitored through electroencephalography (EEG). The multivariate nature of features from time domain, frequency domain, complexity and wavelet entropy based, and the statistical features were extracted from healthy and epileptic subjects using the Bonn University database and seizure and non-seizure intervals using the CHB MIT database. The robust machine learning regression methods based on regression, support vector regression (SVR), regression tree (RT), ensemble regression, Gaussian process regression (GPR) were employed for detecting and predicting epileptic seizures. Performance was measured in terms of root mean square error (RMSE), squared error, mean square error (MSE) and mean absolute error (MAE). Moreover, detailed optimization was performed using a RT to predict the selected features from each feature category. A deeper analysis was conducted on features and tree regression methods where optimal RMSE and MSE results were obtained. The best optimal performance was obtained using the ensemble boosted regression tree (BRT) and exponential GPR with an RMSE of 0.47, an MSE (0.22), an R Square (RS) (0.25) and an MAE (0.30) using the Bonn University database and support vector machine (SVM) fine Gaussian with RMSE (0.63634), RS (0.03), MSE (0.40493) and MAE (0.31744); squared exponential GPR and rational quadratic GPR with an RMSE of 0.63841, an RS (0.03), an MSE (0.40757) and an MAE (0.3472) was obtained using the CHB MIT database. A further deeper analysis for the prediction of selected features was performed on an RT to compute the optimal feasible point, observed and estimated function values, function evaluation time, objective function evaluation time and overall elapsed time.
Nonlinear response of axially functionally graded Timoshenko beams on elastic foundation under harmonic excitation
Authors: Lohar Hareram , Mitra Anirban , Sahoo Sarmila 
Published: May 2019

Abstract
Forced vibration of non-uniform axially functionally graded (AFG) Timoshenko beam on elastic foundation is performed under harmonic excitation. A linear elastic foundation is considered with three different classical boundary conditions. AFG materials are an advanced class of materials that have potential for application in various engineering fields. In the present work, variation of material properties along the longitudinal axis of the beam are considered according to power-law forms. Five values of material gradation parameter provides different functional variation and their effect on the frequency response of the system is studied. The present approximate method is displacement based and Von-Karman type of geometric nonlinearity is considered with rotational component to incorporate transverse shear. Hamilton’s principle is used to derive nonlinear set of governing equation and Broyden method is implemented to solve the nonlinear equations numerically. The results are successfully validated with previously published article. Frequency vs. amplitude curve corresponding to different combinations of system parameters are presented and are capable of serving as benchmark results. A separate free vibration analysis is undertaken to include backbone curves with the frequency response curves in the non-dimensional plane.
An analytical solution for static problems of curved composite beams
Authors: Ecsedi István , Lengyel Ákos József 
Published: May 2019

Abstract
An analytical solution is presented for the determination of deformation of curved composite beams. Each cross-section is assumed to be symmetrical and the applied loads are acted in the plane of symmetry of curved beam. In-plane deformations are considered of composite curved beams. Assumed form of the displacement field assures the fulfillment of the classical Bernoulli-Euler beam theory. The curvature of beam is constant and the internal forces in a cross-section is replaced by an equivalent forcecouple system at the origin of the cylindrical coordinate system used. The internal forces are expressed in terms of two kinematical variables, which are the radial displacement and the rotation of the cross-sections. The determination of the analytical solutions of the considered static problems are based on the fundamental solutions. Linear combination of the fundamental solutions which are filling to the given loading and boundary conditions, gives the total solution. Closed form formulae are derived for the radial displacement, cross-sectional rotation, nomral and shear forces and bending moments. The circumferential and radial normal stresses and shear stresses are obtained by the integration of equilibrium equations. Examples illustrate the developed method.
History and Future of KALIS: Towards Computer-assisted Decision Making in Prescriptive Medicine
Authors: Friedrichs Marcel , Shoshi Alban 
Published: May 2019

Abstract
With an increasing older population in Germany and the need for polypharmacy to treat multimorbid patients computer-assisted decision making on an individual level is increasingly important to reduce prescription errors and adverse drug reactions. While current systems focus on guidelines and prescribing information, molecular information is equally important for explanation and discovery of drug-related problems. Based on the existing KALIS system and newer projects like PIMBase, a new concept for the KALIS-2 system is presented. Improvements to the modularisation of components enable future extension and greater maintainability. Interoperability with available electronic health records standards and protocols allows the integration and communication with existing workflows for healthcare professionals. Finally, new visualisation modes empower the user to explore and analyze the patient situation in an individual patient subgraph. For offline use and dialogue between patient and general practitioner, the results can be printed out using a new reporting tool. The adherence to findings from previous decision support systems and reasons for their failed adoption is an important task in the development of KALIS-2.
Research on CLIB Routing and Spectrum Allocation Algorithm in Elastic Optical Networks
Authors: Li Li , Ya-Fang Zhai , Hong-Jie Li 
Published: May 2019

Abstract
With the rapid development of mobile Internet, high-definition video and cloud computing, users’ bandwidth demands are not only larger and larger but also more and more diverse. To solve this problem, there searchers put forward the concept of elastic optical network (EON). EON adopts the transmission mode of elastic grid, which can allocate spectrum resources flexibly and meet high bandwidth and diversity requirements at the same time. Routing and spectrum allocation (RSA) is an important issue in EON. In this paper, we present a heuristic algorithm named constrained-lower-indexed-block (CLIB) allocation algorithm for the RSA problem. The algorithm is based on the K candidate paths. When there are available spectrum blocks on multiple candidate paths, if the increase of the path length does not exceed a given threshold, the lower index spectrum would be selected for the connection request on a longer path. The aim of the algorithm is to concentrate the occupied frequency slices on one side of the spectrum and leave another side of the spectrum to the later arrived connection requests as much as possible, to reduce the blocking probability of connection requests. Simulation results show that comparing with the first-last-fit and hybrid grouping algorithms, the CLIB algorithm can reduce the blocking probability of connection requests.
Optical trapping in vivo: theory, practice, and applications
Authors: Favre-Bulle Itia A. , Stilgoe Alexander B. , Scott Ethan K. , Rubinsztein-Dunlop Halina 
Published: May 2019

Abstract
Since the time of their introduction, optical tweezers (OTs) have grown to be a powerful tool in the hands of biologists. OTs use highly focused laser light to guide, manipulate, or sort target objects, typically in the nanoscale to microscale range. OTs have been particularly useful in making quantitative measurements of forces acting in cellular systems; they can reach inside living cells and be used to study the mechanical properties of the fluids and structures that they contain. As all the measurements are conducted without physically contacting the system under study, they also avoid complications related to contamination and tissue damage. From the manipulation of fluorescent nanodiamonds to chromosomes, cells, and free-swimming bacteria, OTs have now been extended to challenging biological systems such as the vestibular system in zebrafish. Here, we will give an overview of OTs, the complications that arise in carrying out OTs in vivo, and specific OT methods that have been used to address a range of otherwise inaccessible biological questions.
Military Non-State Actors in Syrien und im Irak – Eine Bestandsaufnahme
Authors: Sahin Kaan 
Published: May 2019

Zusammenfassung
Seit dem Arabischen Frühling 2011 und der damit zusammenhängenden fragilen Staatlichkeit in den Ländern des Nahen Osten ist die Anzahl der militärischen nichtstaatlichen Akteure in der Region stark angewachsen. Vor diesem Hintergrund untersucht der folgende Beitrag die politische Bedeutung dieser Akteure in den ausgewählten Ländern Syrien und Irak. Unter dem Terminus „Military Non-State Actors“ (MNSA) wird eine Kategorisierung und Bestandsaufnahme aller relevanten Akteure vorgenommen. Nach der Darstellung ihrer Relevanz und im Anschluss an die Verortung mithilfe der zuvor aufgestellten Kategorisierung werden die Probleme und Konsequenzen für die Staaten Iran, Russland, die Türkei und die USA aufgezeigt. Am Schluss wird unter Einbeziehung der Interessen der MNSA und der relevanten Staaten eine Analyse der zukünftigen großen Konfliktpunkte und Herausforderungen vorgenommen, die sich in diesem Zusammenhang abzeichnen.
Optimal growth in the Robinson-Shinkai-Leontief model: the case of capital-intensive consumption goods
Authors: Deng Liuchun , Fujio Minako , Khan M. Ali 
Published: May 2019

Abstract
We study the two-sector Robinson-Shinkai-Leontief (RSL) model of discrete-time optimal economic growth for the case of capital-intensive consumption goods. We frame the model in the context of Nishimura’s oeuvre, and more specifically, relate it to its neoclassical cousin: the Uzawa-Srinivasan continuous-time version studied in Haque, W. 1970. “Sceptical Notes on Uzawa’s ‘Optimal Growth in a Two-Sector Model of Capital Accumulation’, and a Precise Characterization of the Optimal Path.” The Review of Economic Studies 37: 377–394. We take Fujio’s identification of the marginal rate of transformation ζ of capital goods today into capital goods tomorrow (Fujio, M. 2006. Optimal Transition Dynamics in the Leontief Two-Sector Growth Model. Ph.D. thesis, The Johns Hopkins University), and using a mix of the Bellman-Blackwell methods of dynamic programming and the value-loss approach of Brock-Mitra, pin down the optimal policy for a specific subset of the parameter space. We discern a bifurcation pattern with respect to the discount factor that echoes the results of Benhabib, J., and K. Nishimura. 1979. “The Hopf Bifurcation and the Structure and Stability of Closed Orbits with Heterogeneous Steady States in Multi-Sector Models of Optimal Growth.” Journal of Economic Theory 21: 421–444 for the neoclassical model, and Khan, M. A., and T. Mitra. 2005. “On Choice of Technique in the Robinson-Solow-Srinivasan Model.” International Journal of Economic Theory 1: 83–110 for the RSS model. We also study the optimal policy correspondence for a general parameter set.
The impact of language contact on Hinuq
Authors: Forker Diana 
Published: May 2019

AbstractThis paper investigates the impact of language contact on the Nakh-Daghestanian language Hinuq. Hinuq is a rather small language that has been in contact with larger languages for several centuries; among them the traces of Avar and Russian are particularly visible. The paper provides an overview about all observable influences on the phonology, morphology and syntax of Hinuq as well as on the lexicon. Avar is the main source for borrowed morphology and loan words. The influence of Russian on the Hinuq lexicon is growing, especially among the young speakers, but it is still smaller compared to Avar. With respect to the syntax no Avar impact can be detected since the languages belong to the same language family and large parts of the syntactic features and rules bear strong resemblances in the two languages. By contrast, Russian, which is genetically unrelated and typologically different from Hinuq, has some influence on the Hinuq constituent order.
At the threshold: A case study of a partnership between a student organization and an educational development center
Authors: Doktor Stephanie DeLane , Bach Dorothe , Abbot Sophia , Hardin Jacob 
Published: May 2019

This article offers a case study about the collaboration between a student-led organization and an academic development unit dedicated to improving teaching and learning at [Institution 2]. We describe the genesis of our collaboration, how we nurtured and developed it over time into a substantive program, and what we learned in the process. While most existing case studies focus on partnerships between students and faculty, we turn the lens inward and investigate the challenges involved in enacting an “ethic of reciprocity” (Cook-Sather and Felten, 2017) in a partnership between an academic development center and a student organization. Using the analytical framework of threshold concepts, we explore the rocky navigating of issues of trust, vulnerability, role confusion, the notion of expertise, and pre-existing power inequalities to move towards a more collaborative and equitable partnership.
Historical and Social Considerations of Strength Training for Female Athletes
Authors: Shurley Jason , Felkar Victoria , Greviskes Lindsey , Todd Jan 
Published: May 2019

ABSTRACT
Female athletes may be hesitant to fully engage in the weight room. Common concerns include violating social norms through their muscularity, or a lack of competence in strength training. These concerns are rooted in historical efforts to constrain the intensity of female competition and traditional societal assumptions about the attributes of femininity. This work seeks to help strength coaches understand the historical and social background of female concerns about strength training and provides a psychological framework that may be useful in helping female athletes overcome their trepidation about the weight room.
Mitochondrial mutation m.3243A>G associates with insulin resistance in non-diabetic carriers
Authors: Langdahl Jakob Høgild , Frederiksen Anja Lisbeth , Vissing John , Frost Morten , Yderstræde Knud Bonnet , Andersen Per Heden 
Published: May 2019

Aim
This case–control study aimed to examine impairments in glucose metabolism in non-diabetic carriers of the mitochondrial mutation m.3243A>G by evaluating insulin secretion capacity and sensitivity.

Methods
Glucose metabolism was investigated in 23 non-diabetic m.3243A>G carriers and age-, sex- and BMI-matched healthy controls with an extended 4-h oral glucose tolerance test (OGTT). Insulin sensitivity index and acute insulin response were estimated on the basis of the OGTT. This was accompanied by examination of body composition by dual-energy X-ray absorptiometry (DXA), maximum aerobic capacity and a Recent Physical Activity Questionnaire (RPAQ).

Results
Fasting p-glucose, s-insulin and s-c-peptide levels did not differ between m.3243A>G carriers and controls. Insulin sensitivity index (BIGTT-S1) was significantly lower in the m.3243A>G carriers, but there was no difference in the acute insulin response between groups. P-lactate levels were higher in carriers throughout the OGTT. VO2max, but not BMI, waist and hip circumferences, lean and fat body mass%, MET or grip strength, was lower in mutation carriers. BIGTT-S1 remained lower in mutation carriers after adjustment for multiple confounding factors including VO2max in regression analyses.

Conclusions
Glucose metabolism in m.3243A>G carriers was characterized by reduced insulin sensitivity, which could represent the earliest phase in the pathogenesis of m.3243A>G-associated diabetes.
Hybrid Silica Based Materials as New Solid Phase
Extractants.
Authors: Bourg Stéphane , Broudic Jean-Charles , Conocar Olivier , Moreau Joël J.E. , Meyer Daniel , Wong Chi Man Michel 
Published: May 2019

ABSTRACTOrganic-inorganic hybrids exhibiting specific properties are easily prepared
by incorporation of organic fragments in an inorganic network. Increasing
attention is being paid to hybrid silsesquioxane gels, which are prepared by
sol-gel hydrolysis condensation of organic molecules containing two or more
trialkoxysilyl substituents. These hybrids consist of a mixed
three-dimensional network, where the organic fragment, cross-linking
siloxane chains, is part of the framework. Owing to the presence of a strong
Si-C bond between the organic and the inorganic fragments, highly stable
hybrid network are produced in this way. A variety of materials can be
produced according to the intrinsic properties of the organic. We report
here the preparation of hybrid materials with complexing properties upon
hydrolysis-condensation of ligands functionalized by Si (OR)3
groups. New hybrid silica based materials containing malonamide ligands have
been prepared by sol-gel hydrolysis condensation of functionalized
precursors and have been used as solid phase extractants for the
complexation of actinides. This approach is quite different from the
classical immobilization procedure of complexing agents. The sol-gel
approach allows one to adjust the ligand loading and to achieve some control
and some tuning of the ligand environment since the oxide matrix is built
around the complexing moieties. These hybrids proved to be highly efficient
extracting solids.
The U. S. Army Reactive Topical Skin Protectant (rTSP):
Challenges and Successes
Authors: Hobson Stephen T. , Lehnert Erich K. , Braue Ernest H. 
Published: May 2019

ABSTRACTIn 1994, the U. S. Army initiated a research effort towards an effective
material that acts both as a protective barrier and as an active destructive
matrix against chemical warfare agents (CWA). We report results on our
preparation and evaluation of Reactive Topical Skin Protectants (rTSP's).
These creams are composite materials consisting of a base material (TSP) and
a reactive moiety. Using an established base of perfluorinated-polyether and
perfluoropolyethylene solids we incorporated over 60 reactive components.
Classes tested include organic polymers, organic/inorganic hybrid materials,
polyoxometallates (POM's), enzymes, inorganic oxides, metal alloys and small
molecules. We characterized these materials by light microscopy and FTIR. We
determined the efficacy of these materials against both sulfur mustard (HD)
and a representative nerve agent, soman (GD), using a penetration cell model
coupled to a continuous air monitor and also by in vivo
testing. Composite materials with optimum reactive compounds exhibit a 94%
reduction of GD vapor break-through after 20 hours (from 9458 ng to 581 ng)
and a 3.6 fold increase (from 162 min to 588 min) in the time 1000 ng of GD
liquid penetrates through the material. Similar composite materials show a
99% reduction in HD vapor break-through after 20 hours (from 4040 ng to 16
ng), a 2.3 fold increase (from 524 min to >1200 min) in the time 1000 ng
of HD vapor penetrates through the material, and an elimination of erythema
versus control in an HD vapor challenge. These results indicate that an rTSP
that protects against sulfur mustard and nerve agents is within reach.
Crosslinked Organic-Inorganic Hybrid Thin Films for Corrosion
Resistance: Spectroscopic and Salt Spray Characterization
Authors: Metrokeand Tammy L. , Knobbe Edward T. 
Published: May 2019

ABSTRACTSpray-coated, R-Si (OR')3 / TMOS (R = epoxide), thin films are
being investigated as room temperature curing corrosion resistant coatings
for 2024-T3 aluminum alloy. Solid state 1H-13C CP/MAS
NMR indicates that primary aliphatic amines and super acids are effective
crosslinkers for epoxide groups in aqueous ormosil systems. Incorporation of
a crosslinking agent into the coating was found to reduce the cure time of
the deposited film from >7 days to approximately 30 min. Accelerated salt
spray and filiform corrosion resistance tests were conducted to determine
the effects of crosslinking on the corrosion resistance behavior of ormosil
thin films. The choice of curing agent was found to influence film structure
and corrosion resistance properties. Amine cured thin films were hard and
highly adherent to the aluminum alloy substrates, exhibiting excellent bare
and filiform corrosion resistance, in addition to good compatibility with
organic polymer paint systems. In contrast, the adhesion and corrosion
resistance of super acid cured thin films to aluminum alloy substrates was
significantly less, producing films which readily delaminated from the
substrate. These observations can be related to the film structure.
Hybrid Inorganic/Organic Diblock Copolymers. Nanostructure in
Polyhedral Oligomeric Silsesquioxane Polynorbornenes.
Authors: Haddad Timothy S. , Mather Patrick T. , Jeon Hong G. , Chun Seung B. , Phillips Shawn H. 
Published: May 2019

ABSTRACTOur main approach to the synthesis and study of hybrid organic/inorganic
materials involves incorporating nano-size inorganic polyhedral oligomeric
silsesquioxane (POSS) clusters into various polymeric resins. A typical POSS
cluster is a discrete silicon and oxygen framework solubilized with organic
groups and contains a single reactive site. This lone site of reactivity is
used to covalently attach the inorganic macromers pendent to a polymer
backbone without causing any crosslinking. This strategy permits the
synthesis of melt processable, linear hybrid polymers containing pendent
inorganic clusters, and allows us to study the effect these clusters have on
chain motion, polymer properties and morphology. The synthesis of
norbornenyl-based (POSS) macromers, their ring opening metathesis
copolymerizations with varying amounts of norbornene, and analysis of the
effect of the pendent POSS group is presented. Ring opening metathesis
polymerization permits the easy synthesis of both random and diblock
copolymers. Transmission electron microscopy (TEM) clearly images POSS-rich
domains against the POSS-free regions. Major differences in polymer
morphology are observed as the amount of inorganic POSS is varied, between
random and diblock copolymers, as well as between polymers that differ only
in the solubilizing cycloalkyl groups on the POSS cluster.