bluuebunny/crossref_metadata_2025_split huggingface dataset:
Message from Editor
Authors: Tayauova Prof. Dr. Gulzhanat 
Published: November 2018

Message from Editor

Dear Readers,

It is the great honor for us to publish seventh volume, second issue of Global Journal of Business, Economics and Management: Current Issues.

Global Journal of Business, Economics and Management: Current Issues is an international, multi-disciplinary, peer-refereed journal which aims to provide a global platform for professionals working in the field of business, economics, management, accounting, marketing, banking and finance and scholars and researchers to share their theoretical, empirical and practical knowledge on current issues in the area of business, economics and management.

The scope of Global Journal of Business, Economics and Management: Current Issues includes; but is not limited to current issues on; Accounting, Advertising Management, Business and Economics, Business Ethics, Business Intelligence, Business Information Systems, Business Law, International Finance, Labor Economics, Labor Relations & Human Resource Management, Law and Economics, Management Information Systems, Business Law, Business Performance Management, Business Statistics, Communications Management, Comparative Economic Systems, Consumer Behavior, Corporate Finance and Governance, Corporate Governance, Cost Management, Management Science, Market Structure and Pricing, Marketing Research and Strategy, Marketing Theory and Applications, Operations Research, Organizational Behavior & Theory, Organizational Communication, Prices, Business Fluctuations, and Cycles, Product Management, Decision Sciences, Development Planning and Policy, Economic Development, Economic Methodology, Economic Policy and so on.

Aim of this issue is to give the researchers an opportunity to share the results of their academic studies. There are different research topics discussed in the articles. Topics including a case study on reading news and ICT as a motivational tools in teaching, Responsible sourcing practices in hazelnut industry, applicable quality management tools in a production cycle of a selected company, brand positioning of domestic services in Australia and significant leadership competencies at large industrial companies: Results of exploratory quantitative research are included in the current issue.

The topics of the next issue will be different. You can make sure that we will be trying to serve you with our journal to provide a rich knowledge of the field. Different kinds of topics will be discussed in 2018 Volume. A total number of thirteen (13) manuscripts were submitted for this issue and each paper has been subjected to double-blind peer review process by the reviewers specialized in the related field. At the end of the review process, a total number of five (5) high quality research papers were selected and accepted for publication.

We present many thanks to all the contributors who helped us to publish this issue.

Best regards,

Prof. Dr. Gulzhanat Tayauova

Editor â€“ in Chief
Diagnosis winding short-circuit faults of power transformer
Authors: Badri Rekik , Hocine Labar 
Published: November 2018

Diagnostic goal of transformers in service is to detect the winding or the core in fault. Transformers are valuable equipment which makes a major contribution to the supply security of a power system. Consequently, it is of great importance to disequilibria the three phases courant of power transformers. So, vector diagram Analysis is useful tool for reliable detection of incipient mechanical fault in a transformer, by finding winding or core defects. The authors propose this article, the coupled circuits method, because, it gives most possible exhaustive modelling of transformers. Measurement courant homopolaire in order to improve and simplify the response for Ã faults transformer.This study can be useful as a base data for the other transformers of the same categories intended for distribution grid.
Keywordsâ€”Diagnostic; Short-Circuit; Transformer Faults; unbalanced current.
Message from Editor
Authors: Ibrahim Dogan 
Published: November 2018

Message from Editor
Dear Readers,
It is a great honor for us to publish Volume 8, Issue 2 of Global Journal of Computer Sciences: Theory and Research.
Global Journal of Computer Sciences: Theory and Research (GJCS) is an international online journal for scientists and professionals involved in all aspects of computer sciences. This journal serve s as an international platform that fosters theoretical and practical issues and new applications for all scientists and professionals from the field of computer sciences including original research and innovative applications from all parts of the world.
Aim of this issue is to give the researchers an opportunity to share the results of their academic studies. There are different research topics discussed in the articles. Articles focusing on Aref Shirazi, Adel Shirazy, Ardeshir HezarKhani, Introducing a software for innovative neuro-fuzzy clustering method named NFCMR, Rekik Badri, Labar Hocine, Diagnosis winding short-circuit faults of power transformer, Benhamida Hakim, Mesbah Tarek, Study and identification of short-circuit currents at the Complex Distribution Network SIDER-EL Hadjar (ex ArceloMittal-Algerie), Nadia Ben Si Ali, Nora Zerzouri, Nadia Benalia, Modelling and power control of grid-connected wind energy system are included in the current issue.
A total number of twelve (10) manuscripts were submitted for this issue and each paper has been subjected to double-blind peer review process by the reviewers specialized in the related field. At the end of the review process, a total number of six (4) high quality research papers were selected and accepted for publication.
We present many thanks to all the contributors who helped us to publish this issue. Best regards,
Prof. Dr. Dogan Ibrahim Editor â€“ in Chief
Reverse Engineering Reverse Engineering Analysis Forensic Malware WEBC2-Div
Authors: Waliulu Raditya Faisal 
Published: November 2018

At this paper focus on Malicious Software also known as Malware APT1 (Advance Persistent Threat) codename WEBC2-DIV the most variants malware has criteria consists of Virus, Worm, Trojan, Adware, Spyware, Backdoor either Rootkit. Although, malware could avoidance scanning antivirus but reverse engineering could be know how dangerous malware infect computer client. Lately, malware attack as a form espionage (cyberwar) one of the most topic on security internet, because of has massive impact. Forensic malware becomes indicator successful user to realized about malware infect. This research about reverse engineering. A few steps there are scanning, suspected packet in network and analysis of malware behavior and disassembler body malware.
Hydroalcoholic Extract of Cuscuta Epithymum Enhances Pentobarbitalinduced Sleep: Possible Involvement of GABAergic System
Authors: Forouzanfar Fatemeh , Vahedi Mohammad M. , Aghaei Azita , Rakhshandeh Hassan 
Published: November 2018

Background:
Insomnia is the most common sleep disorder. The present study was undertaken to
evaluate the sedative-hypnotic potential of hydroalcoholic extract (HAE) of Cuscuta epithymum and its fractions.

Methods:
HAE and its fractions including: water fraction (WF), ethyl acetate fraction (EAF) and n-hexan
fraction (NHF) were i.p administered to male mice and 30 min later pentobarbital (30 mg/kg, i.p.) was injected
to induce sleep. Then the latent period and continuous sleeping time were recorded. Besides, 30
mins after administration of HAE motor coordination (rota-rod test) were assessed. Additionally, LD50 of
HAE was determined and the possible neurotoxicity of the extract was tested on neural PC12 cells.

Results:
The HAE and NHF decreased the latency of sleep and significantly increased the duration of
sleep induced by pentobarbital. These effects of C. epithymum were reversed by flumazenil. HAE did not
affect the animals’ performance on the rotarod test. The LD50 value for HAE was found to be 4.8 g/kg.
HAE and its fractions had no toxicity effect on the viability of PC12-cell line.

Conclusion:
The results of the present study indicate that the HAE and NHF have significant sedativehypnotic
effects in mice without major toxic effect and that the benzodiazepine receptors are involved in
the sedative-hypnotic effects of this plant.
Investigating the Relationship the Severity of Coronary Artery Disease with Serum Levels of Vitamin D in Men after Eliminating the Effect of Diet
Authors: Birgani Farshad K. , Shahi Majid M. , Cheraghian Bahman , Haybar Habib 
Published: November 2018

Background:Coronary artery disease (CAD) is one of the most common cardiovascular diseases that can lead to mortality, inability, and lower productivity levels.Objective:The aim of this study was to determine the relationship between serum vitamin D level and cardiovascular risk factors and the severity of CAD after determining and eliminating the confounding effects of dietary patterns in male patients undergoing angiography.Methods:This descriptive-analytic study was carried out on 132 men undergoing angiography during 2017 and 2018. To this end, food frequency questionnaire (FFQ) and physical activity questionnaire (PAQ) were completed for the patients. Fasting blood sugar (FBS), triglyceride, total cholesterol, HDL-C, LDL-C and vitamin D levels were also investigated.Results:Serum vitamin D levels significantly decreased with an increase in CAD severity (p=0.001). Also, low serum levels led to the highest severity of CAD (p=0.005). However, there was no significant difference between patients with vitamin D deficiency with different degrees of CAD (p=0.084). Also, the highest percentage of individuals with normal serum levels of vitamin D was observed in the group without any blocked blood arteries (normal) (p=0.023).Conclusion:This study shows an inverse relationship between serum 25(OH) D level and the severity of CAD. Our data show that vitamin D plays an important role in preventing CAD. These findings could help design prospective studies and clinical trials on a wider scale to investigate the effects of vitamin D interventions in preventing the development of CAD.
Clinical Research on the Aortic Elasticity in Patients with Type 1 Diabetes Mellitus Complicated with Hypertension
Authors: Wang Zheng , Wan Yulei 
Published: November 2018

Background:
To investigate the characteristics of aortic elasticity in type 1 diabetes mellitus
(DM1) patients with hypertension using dual-source computed tomography (DSCT).

Methods:
Subjects were divided into four groups: 31 with hypertension (EH group), 28 with DM1
(DM1 group), 30 with hypertension and DM1 (DM1 + EH group), and 30 healthy volunteers (control
group, CG). ECG-gated DSCT was used to measure the cross-sectional area of the aorta in diastole
and systole and calculate the aortic elasticity (D). Analysis of variance and multiple linear regression
were used for statistical analysis.

Results:
Compared with the CG, aortic elasticity (D) in the DM1 group patients was not significantly
decreased. Compared with the EH group, the DM1 + EH group showed no significant change.
The aortic elasticity (D) in the EH and DM1 + EH groups was significantly lower than that in the
CG and DM1 group.

Conclusion:
DM1 slightly affects the aortic elasticity of the descending aorta, whereas hypertension
exerts the main effect.
Design, Synthesis and In Vitro Evaluation of Novel Anti-HIV 3-Pyrazol-3- yl-Pyridin-2-One Analogs
Authors: Kumar Sanjay , Gupta Shiv , Gaikwad Shraddha , Abadi Leila F. , Bhutani Late K. K. , Kulkarni Smita , Singh Inder P. 
Published: November 2018

Background:
Natural products have shown potent anti-HIV activity, but some of these
also possess toxicity. The pharmacophoric fragments of these natural products have scope of combination
with other pharmacophoric fragment and derivatization to reduce toxicity and increase the
potency. Combination of natural product fragments from different classes of anti–HIV compounds
may lead to a new class of potent anti–HIV agents.

Objective:
Design, in silico prediction of drug-likeness, ADMET properties and synthesis of pyrazol–
pyridones. Evaluation of the anti–HIV–1 activity of synthesized pyrazol–pyridones.

Methods:
Pyrazol–pyridones were designed by combining reported anti–HIV pharmacophoric
fragments. Designed molecules were synthesized after in silico prediction of drug-likeness and
ADMET properties. Compounds were evaluated for activity against HIV–1VB59 and HIV–1UG070.

Results:
QED value of designed pyrazol–pyridones was greater than the known drug zidovudine.
The designed compounds were predicted to be noncarcinogenic and nonmutagenic in nature. Seventeen
novel pyrazol–pyridones were synthesized with good yield. Compound 6q and 6l showed
activity with IC50 values 6.14 µM and 15.34 µM against HIV–1VB59 and 16.21 µM and 18.21 µM
against HIV–1UG070, respectively.

Conclusion:
Compound 6q was found to be most potent among the synthesized compounds with a
therapeutic index of 54.31against HIV–1VB59. This is the first report of anti–HIV–1 activity of
pyrazol–pyridone class of compounds. Although the anti–HIV–1 activity of these compounds is
moderate, this study opens up a new class for exploration of chemical space for anti–HIV–1 activity.
Application of an LC-MS/MS Method to a Urinary Excretion Study of Triflusal and its Main Metabolite 2-hydroxy-4-trifluoromethyl Benzoic Acid in Human Urine
Authors: Ge Jie , Wang Jin-Wen , Guo Qi-Yan , Wen Ai-Dong 
Published: November 2018

Objective:
A validated liquid chromatography-tandem mass spectrometry method (LCMS/
MS) was established to simultaneously determine the concentration of triflusal and its main
metabolite 2-hydroxy-4-trifluoromethyl benzoic acid(HTB) in human urine.

Methods:
The separation was performed on a Dikma C18 column using isocratic elution with
acetonitrile-4 mmol/L ammonium acetate aqueous solution containing 0.3 % formic acid water (78: 28,
V/V). The method involved extraction with methanol using protein precipitation. The precursor-toproduct
ion transitions with multiple reaction monitoring was m/z 247.1→161.1, 204.8→106.7and
136.9→93.0 for triflusal, HTB and salicylic acid(IS), respectively. The method showed good linear
relationships over the ranges of 0.08 to 48 μg/mL and0.5 to 50 μg/mL.

Results:
It was the first time that a urinary excretion study of triflusal capsule as oral. The cumulative
urinary recovery showed 8.5% and 2.7% for triflusal and HTB, respectively.

Conclusion:
This method was successfully used for evaluating the pharmacokinetic properties of triflusal
and HTB in urine in Chinese healthy subjects.
Cardiotoxicity Associated with Midazolam in a Patient with Diphtheria
Authors: Gohil Jayendra R. , Jindal Sonal 
Published: November 2018

Background:
Adverse cardiorespiratory events are associated with midazolam continuous IV infusion, used for sedation.

History:
Here we are reporting a case of 5 year old male child suffering from diphtheria induced
airway obstruction, and myocarditis, who received midazolam in the form of IV infusion for sedation
while undergoing mechanical ventilation for respiratory failure.

Adverse Event:
Six hours after starting midazolam infusion he started developing pulsus bigeminus
and bradycardia and eventual death after two hours.

Conclusion:
Midazolam, although considered one of the safest drugs, need to be used cautiously in a
child with myocarditis, because of the possible cardiotoxic effect in an already affected heart.
Synthesis and Evaluation of 3-(1,3-dioxoisoindolin-2-yl)-N-substituted Phenyl Benzamide Analogues as HIV Integrase Strand Transfer Inhibitors
Authors: Wadhwa Pankaj , Jain Priti , Patel Arpit , Shinde Shantanu , Jadhav Hemant R. 
Published: November 2018

<P>Background: A series of novel 3-(1,3-dioxoisoindolin-2-yl)-N-substituted phenyl benzamide
derivatives was synthesized and tested in vitro against human immunodeficiency virus
type-1 Integrase (HIV-1 IN).

Methods:
Out of the 18 analogues, six (compounds 16c, 16h, 16i, 16m, 16n and 16r) showed significant
inhibition of strand transfer by HIV-1 integrase. For these six compounds. IC50 was below
5.0 µM. In silico docking studies revealed that the presence of 2-phenyl isoindoline-1,3-dione motif
was essential as it was found to interact with active site magnesium.

Results:
To further confirm the results, cell-based HIV-1 and HIV-2 inhibitory assay was carried out.

Conclusion:
These compounds possess structural features not seen in previously reported HIV-1
integrase inhibitors and thus can help further optimization of anti-HIV-1 integrase activity.</P>
Sonic Stimulation and Low Power Microwave Radiation Can Modulate Bacterial Virulence Towards Caenorhabditis elegans
Authors: Patel Priya , Patel Hiteshi , Vekariya Dhara , Joshi Chinmayi , Patel Pooja , Muskal Steven , Kothari Vijay 
Published: November 2018

<P>Background: In view of the global threat of antimicrobial resistance, novel alternative approaches to deal with infectious bacteria are warranted, in addition to the conventional invasive therapeutic approaches.Objective:This study aimed at investigating whether exposure to sonic stimulation or microwave radiation can affect virulence of pathogenic bacteria toward the model nematode host Caenorhabditis elegans.Methods:Caenorhabditis elegans worms infected with different pathogenic bacteria were subjected to sonic treatment to investigate whether such sound treatment can exert any therapeutic effect on the infected worms. Virulence of microwave exposed bacteria was also assessed using this nematode host.Results:Sound corresponding to 400 Hz, and the divine sound ‘Om’ conferred protective effect on C. elegans in face of bacterial infection, particularly that caused by Serratia marcescens or Staphylococcus aureus. The observed effect seemed to occur due to influence of sound on bacteria, and not on the worm. Additionally, effect of microwave exposure on bacterial virulence was also investigated, wherein microwave exposure could reduce virulence of S. aureus towards C. elegans.Conclusion:Sonic stimulation/ microwave exposure was demonstrated to be capable of modulating bacterial virulence.</P>
Safety of Pharmaceutical Excipients and Regulatory Issues
Authors: Ramesh Kanteti V.R.N.S. , Yadav Hemant , Sarheed Omar 
Published: November 2018

Background:Pharmaceutical excipients are critical in the formulation of any dosage form. Not many additives employed in the drug product manufacture have properties, which meet the desired qualities that the finished product must have. Therefore, it is mandatory to mix the drug substance with other substances to overcome the deficiencies. As a result, almost all pharmaceutical products are mixtures of active pharmaceutical ingredient and additives. So, there is a compelling need of these substances and normally they occupy the major part of any drug product. Excipients are of different chemical categories that have varying physicochemical properties like solubility, miscibility and the nature and source of these materials vary. With growing number of pharmaceutical excipients and polymers, the question of evaluating their toxicity is becoming a complex issue. Many polymers and novel excipients are now available in the market and with their diverse chemical nature and different sources and presence of impurities and their adverse effects will further complicate the safety profiling of these excipients.Conclusion:This review article will discuss the unwanted biological activities of some commonly used excipients and issues of the supply of the pharmaceutical excipients that need to be highly regulated and monitored to ensure availability of quality and pure excipient compounds.
Assessment of Heavy Metals Contamination in Drinking Water of Garmian Region, Iraq
Authors: Issa Hayder Mohammed , Alshatteri Azad 
Published: November 2018

Drinking water of safe quality is a critical issue for human survival and health. Water pollution by heavy metals is very crucial because of their toxicity. This study assesses potential of heavy metals pollution in drinking water in Garmian Region, East Iraq. Water samples were investigated for 23 heavy metals and 6 chemical contaminants collected from 16 locations. The analysis was performed by using coupled plasma optical emission spectroscopy (ICPOES, Spectro Arcos). High levels of Al, Se, Sr, and Fe have been detected at certain locations in study area. Statistical analysis techniques of the correlation matrix (CM), and cluster hierarchical analysis (CA) were conducted. The heavy metals pollution index (HPI), heavy metals evaluation index (HEI), and contamination Index (Cd) were used applied. These indices linked with the statistical analysis to interpret relationships among the tested parameters in water samples and to investigate the pollution sources over the study region. Even with the significant correlations between the HPI, Cd, and HEI, they showed dissimilar impact of examined heavy metals on the water quality. The most reliable pollution evaluation index of HEI for drinking water showed that 44% of the water samples is critically polluted. Sources of the contamination are most likely coming from natural geological sources. Anthropogenic impact was only noticed at several sites in the study area.
Perlindungan Data Pribadi dan Privasi Penumpang Maskapai Penerbangan pada Era Big Data
Authors: Nugraha Ridha Aditya 
Published: November 2018

AbstractThis article examines issues surrounding airline passenger data protection in the realms of big data phenomenon. The history of privacy, including two landmark cases, shall be elaborated from the beginning to provide a comprehensive discussion. How the airlines operate through utilizing personal data, also their compliance towards the enacted law shall be analyzed. Then the sentiments towards Passenger Name Record Agreement which speaks on behalf of flight security is also being explored. Finally, the article aims to provide some recommendations towards the current drafting of the new Indonesian Data Protection Act draft by taking into account lessons learned from airlines.IntisariThis article examines issues surrounding airline passenger data protection in the realms of big data phenomenon. The history of privacy, including two landmark cases, shall be elaborated from the beginning to provide a comprehensive discussion. How the airlines operate through utilizing personal data, also their compliance towards the enacted law shall be analyzed. Then the sentiments towards Passenger Name Record Agreement which speaks on behalf of flight security is also being explored. Finally, the article aims to provide some recommendations towards the current drafting of the new Indonesian Data Protection Act draft by taking into account lessons learned from airlines.