bluuebunny/crossref_metadata_2025_split huggingface dataset:
La familia Convolvulaceae en el municipio de Victoria, Tamaulipas, México
Authors: Fernández-Puga Estefanía Guadalupe , Mora-Olivo Arturo , McDonald Andrew , De la Rosa-Manzano Edilia 
Published: September 2019

Antecedentes: La familia Convolvulaceae incluye 58 géneros y 1,880 especies de distribución casi cosmopolita. Presenta una diversidad morfológica notable e incluso incluye especies parásitas. En México el conocimiento de las Convolvulaceae es aún escaso, ya que solo pocas áreas cuentan con trabajos de la familia o de alguno de sus géneros.
Preguntas: ¿Cuántas y cuáles especies de Convolvulaceae se encuentran en el municipio de Victoria? ¿Cómo se distribuyen dentro del área de estudio y a nivel mundial?
Especies de estudio: Especies de la familia Convolvulaceae.
Sitio y años de estudio: Victoria, Tamaulipas, México, 2017-2018.
Métodos: Se colectó material botánico y se identificó utilizando bibliografía especializada. Se revisaron ejemplares de herbario y bases de datos en línea. La distribución de las especies en el área de estudio se examinó mediante un análisis de conglomerados.
Resultados: Se registraron nueve géneros, 31 especies con dos taxones infraespecíficos. El género más rico es Ipomoea (13 especies), seguido por Cuscuta (4) y Evolvulus (4). La mayoría de las especies se encuentran por debajo de los 500 m snm, en matorrales y áreas perturbadas. Un alto porcentaje (77.3 %) tiene amplia distribución geográfica y solo dos especies son endémicas de México, una de éstas es endémica de Tamaulipas. Se incluyen claves taxonómicas de los géneros y especies.
Conclusiones: Aunque la familia Convolvulaceae en Victoria, Tamaulipas, no presenta altos valores de riqueza y aún es necesario continuar con las exploraciones, los endemismos nacionales y locales indican que la región es importante desde el punto de vista biogeográfico.
Genotipado por secuenciación de variedades tradicionales de Theobroma cacao (Malvaceae) del Estado de Tabasco, México
Authors: Ricaño-Rodríguez Jorge , Hipólito-Romero Enrique , Ramos-Prado José M. , Cocoletzi-Vásquez Eliezer 
Published: September 2019

Antecedentes: Se identificaron polimorfismos de nucleótidos únicos (SNPs) en Theobroma cacao mediante genotipados por secuenciación. En este documento se comparte por primera vez un conjunto de resultados relacionados con la variabilidad genética y naturaleza de regiones conservadas codificantes de secuencias nucleotídicas reducidas de variedades nativas mexicanas de cacao.
Hipótesis: La obtención de genomas reducidos mediante enzimas de restricción (REs) de especímenes de T. cacao permite caracterizar polimorfismos de nucléotidos únicos (SNPs) así como regiones conservadas codificantes (CDs).
Especie en estudio: Theobroma cacao L. (Malvaceae)
Sitio de estudio y fechas: Las varetas de T. cacao provienen de distintas parcelas agroforestales tradicionales situadas en los municipios de Cárdenas, Huimanguillo, Comalcalco, Paraíso, Jalpa de Méndez y Cunduacán, Tabasco, así como los municipios de Ixtacomitán y Pichucalco, Chiapas, México; y fueron recolectadas e injertadas entre mayo y junio de 2018.
Métodos: Se realizó un genotipado por secuenciación para la caracterización de biobancos, complementado con estudios computacionales de caracterización molecular taxonómica y regiones codificantes, así como evolución mínima de transcritos proteicos.
Resultados: Las muestras de T. cacao poseen distintos porcentajes de SNPs (2 - 11 %) y los análisis de evolución molecular calcularon probabilidades máximas compuestas similares. Se observaron secuencias conservadas en las regiones codificantes de los genomas que predicen ontologías heurísticas reagrupadas evolutivamente en cinco clústeres relacionadas con procesos de transcripción y metabolismo secundario.
Conclusiones: El método GBS permite identificar SNPs en cacao. La caracterización de genomas reducidos determinó la correlación estructural y transcripcional entre muestras y el genoma de referencia del cacao Criollo.
Prophylactic antibiotics in patients with episiotomy following normal vaginal delivery: a randomised clinical trial
Authors: Garala Nirav J. , Nambiar Sabnam S. 
Published: August 2019

Background: Postpartum infectious complications following normal vaginal delivery remains a cause of major concern for the health care professionals due to higher morbidity and mortality and prolonged hospital stays and increased healthcare costs which makes us consider prophylactic use of antibiotics after normal vaginal delivery. On the other hand unjudicious use of antibiotics has led to widespread antibiotic resistance. Therefore this study was carried out to validate the use of prophylactic antibiotics in these patients and their role in prevention of puerperial pyrexia, wound infections and prolonged hospital stay.Methods: This Randomised clinical trial was conducted at KCHC-Kerala Co-operative Hospital Complex, Pariyaram, Kannur District, Kerala from 1st March 2012 to 30th April 2013. Eligible women were randomly assigned to group which does not receive prophylactic antibiotics (Group A) and group receiving prophylactic antibiotics (Group B). Patients in both the groups were examined every day till the patient was discharged from the hospital and observed for signs and symptoms of infected episiotomy wound, puerperial pyrexia and duration of hospital stay was noted.Results: Mean age in years was 25.6 for Group A and 26.2 for Group B. Mean gestational age in both the groups was 37.6 weeks. Mean duration of labour was 6.62 and 6.22 hours for Group A and B respectively. 6 subjects in Group A and 5 subjects in Group B had puerperial pyrexia. 3 Subjects in Group A and 2 subjects in Group B had wound infection. The mean duration of hospital stay for Group A was 4.18 with SD of 1.0 while mean hospital stay for Group B was 4.01 with SD of 1.1.Conclusions: By comparing subjects in both the groups with respect to puerperial pyrexia, wound infection and duration of hospital stay there was no statistical difference in any of the above criteria in both groups. Hence, in view of the risk of allergic reactions, toxicity and the selection of resistant strains the prophylactic administration of antibiotics does not seem to be justified in patients with episiotomy following vaginal delivery as per this study.
KEPEMIMPINAN PEJABAT STRUKTURAL DAN IKLIM ORGANISASI DALAM PRODUKTIVITAS KERJA PEGAWAI PADA DINAS PENDIDIKAN KABUPATEN SUBANG
Authors: Tamam Badrud 
Published: August 2019

The purpose of this study is to empirically examine the contribution of leadership of structural official and organizational climate to employee productivity at Educational Department of Subang District. The method used in this research is descriptive research with quantitative approach. Population of this research amount 116 employee, and determination of respondents using proportional random sampling which amount 54 employee. Data were collected using a questionnaire instruments that was developed in the form of Likert scale. Data processing techniques using path analysis. The results showed that leadership of structural official contribute to employee productivity amount 38,99%, organizational climate contribute to employee productivity amount 21,11%, and simultaneously leadership of structural official and organizational climate significantly contribute to employee productivity amount 60,11%. These results implies that organizational leader should have a good leadership behavior that develop conducive and pleasurable organizational climate. So that employee bring about high job productivity.
Identiﬁcation and application of piwi-interacting RNAs from seminal plasma exosome in Cynoglossus semilaevis
Authors: Bao Baolong , Zhang Bo , zhao Na , Jia Lei , Che Jinyuan , He Xiaoxu , Liu Kefeng 
Published: August 2019

Abstract
Piwi-interacting RNAs (piRNAs) have been linked to epigenetic and

post-transcriptional gene silencing of retrotransposons in germ line cells, particularly in spermatogenesis. Moreover, exosomic piRNAs are promising biomarkers for disease diagnosis and physiological status indication. To determine whether piRNAs from fish germ line cells have similar features, seminal plasma exosomes from half-smooth tongue sole, Cynoglossus semilaevis, were identified, and their small RNAs were sequenced and analysed. We used C. semilaevis because of its commercial value and its sexual dimorphism, particularly the sex reversed ''pseudo-males'' who have a female karyotype, produce sperm, and copulate with normal females to produce viable offspring. We identiﬁed six signature piRNAs as biomarkers in seminal plasma exosomes from males and pseudo-male C. semilaevis. Bioinformatic analysis showed that all six signatures were sex-related, and four were DNA methylation related and transposition-related piRNAs. Their expression proﬁles were veriﬁed by using real-time quantitative PCR. The expression of the signature piRNAs was markedly higher in males than in pseudo-males. The signature piRNAs could be exploited as male specific
biomarkers in this fish. As far as we know, these are first male specific biomarkers in C. semilaevis.Also, it is the first report that piRNAs are employed as biomarkers in fish.These signatures provide an effective tool to explore sex typing in C. semilaevis and may rovide guidance for future research on the generative mechanism of sex reversed ''pseudo-males'' in C. semilaevis.
miR-19a promotes proliferation and migration of lens epithelial cells by regulating AKT/pAKT signaling
Authors: Li Yuanbin , Wang Yanfang , Pu Yadi , Liu Shujun , Zhang Fenglan 
Published: August 2019

Abstract
Background: Posterior capsule opacification (PCO) occurs frequently following surgical treatment of cataracts, representing a common adverse outcome. PCO develops as a result of lens epithelial cell (LEC) transdifferentiation, migration, and proliferation. In the present report we sought to explore the role of microRNA (miR)-19a in this process and to establish the underlying molecular mechanisms.
Methods: miR-19a was transduced into HLE-B3 LECs, with microscopy and RT-qPCR used to confirm transfection efficiency. We then employed MTT, wound healing, and transwell assay approaches to monitor the proliferation and migration of these LECs. We further assessed levels of the proteins PTEN, AKT, and phosphorylated AKT (pAKT) via western blotting in WT and miRNA-transfected cells.
Results: HLE‑B3 proliferation was markedly enhanced by miR-19a transduction, as well the migration activity of these cells (both P<0.01). Furthermore, overexpressing miR‑19a failed to reduce PTEN expression whereas it did enhance pAKT levels within these LECs (P<0.05).
Conclusions: This suggests that miR-19a can enhance LEC proliferation and migratory activity through a mechanism that may be linked with regulating AKT activation and signaling, thus highlighting a potential avenue for therapeutic treatment of PCO patients.
Potential Impact of 2017 American College of Cardiology / American Heart Association High Blood Pressure Guideline on Chinese Adults---How to Face?
Authors: Jiao Yundi , Sun Zhaoqing , Xie Yanxia , Zheng Jia , Li Zhao , Guo Xiaofan , Dai Yue , Sun Yingxian , Zheng Liqiang 
Published: August 2019

Abstract
Background

The current analysis was to estimate the percentage and number of Chinese adults with hypertension and recommended for pharmacological anti-hypertensive treatment according to the 2017 American College of Cardiology / American Heart Association (ACC/AHA) guideline as compared with the 2010 Chinese Guideline.Methods

We used the 2011 data of China Health and Nutrition Survey (CHNS). 12,499 Chinese adults aged ≥ 18 years with complete blood pressure (BP) values were selected for the present analysis.Results

The crude prevalence (95% CI) of hypertension according to the definitions from 2017 ACC/AHA guideline and the 2010 Chinese guideline was 58.0% (57.2% to 58.9%) and 25.4% (24.7% to 26.2%), respectively. Meanwhile, the percentage of recommended anti-hypertensive medications was 31.5% and 28.8%. Among adults who taking anti-hypertensive medications, the percentage of which had above goal BP level was 88.8% compared to 53.3%. Overall, 613.3 million Chinese adults (aged ≥ 18 years) met the definition for hypertension according to the 2017 ACC/AHA guideline, for which was 267.7 million according to the 2010 Chinese guideline. An additional 28.4 million (2.7%) Chinese adults were recommended anti-hypertensive medication.Conclusions

The present analysis revealed that 2017 ACC/AHA hypertension guideline will result in a substantial increase in the percentage and number of Chinese adults defined as having hypertension and a small increase in the percentage of adults who are recommended anti-hypertensive medications compared to the 2010 Chinese guideline. More intensive management and anti-hypertensive medications are suggested to improve the control rate of hypertension among Chinese adults.
Increased levels of serum Hcy and UA as well as the thickness of carotid intima-media correlates with the severity of coronary artery lesions
Authors: Tan Changming , Li Jianming , Zhou Yangzhao , Xu Feng 
Published: August 2019

Abstract
Background

To investigate the correlation between serum homocysteine (Hcy) and uric acid (UA) levels as well as carotid intima-media thickness (IMT) and the severity of coronary artery lesions in elderly patients with coronary heart disease (CHD).Methods

A total of 156 elderly patients with CHD in the experimental group were further divided into low, middle and high score groups. Serum Hcy and UA levels, IMT, Gensini and Sullivan scores were measured and analyzed by Pearson correlation. The risk factors for CHD and the correlation were analyzed by single factor analysis and logistic regression.Results

The serum levels of Hcy, UA and the IMT in the experimental group were significantly higher than those in the control group (all P < 0.001). Gensini scores showed that the levels of serum Hcy, UA, and the IMT in middle and high score groups were significantly higher than those in the low score group, while the high score group had the significant highest level (all P < 0.001). Serum Hcy, UA levels and the IMT were positively correlated with Gensini and Sullivan scores (all P < 0.001). And male gender, smoking, history of hypertension, systolic pressure, pulse pressure, Hcy, UA, IMT, and BMI were independently correlated with the severity of CHD (all P < 0.05).Conclusions

The serum levels of Hcy and UA and the IMT in patients with CHD were significantly increased, and were positively correlated with the severity of coronary artery lesions, which may serve as diagnostic indicators.
Spectrum of Heart diseases in Children presenting to a Paediatric Cardiac Echocardiography Clinic in the Lake Zone of Tanzania: a 7 years overview
Authors: Zuechner Antke , Mhada Tumaini , Majani Naizihijwa G , Sharau Godwin G , Mahalu William , Freund Matthias W 
Published: August 2019

Abstract
Background

Congenital heart diseases (CHD) are among the most common congenital malformations. It is estimated that the incidence of CHD is constant worldwide, but data are rare for most African countries including Tanzania. Even less data are available on the prevalence of acquired heart diseases (AHD) in African children. Rheumatic heart disease is the leading cause of AHD and is remaining a public health concern in Sub-Saharan Africa affecting especially the younger population. Both, CHD and AHD contribute substantially to morbidity and mortality during infancy and childhood.Methods

This hospital-based, retrospective review of the registry at the paediatric cardiac clinic of Bugando Medical Centre in the Lake Zone of Tanzania analysed the spectrum of heart diseases of paediatric patients during their first presentation by using simple descriptive statistics.Results

Between September 2009 and August 2016, a total of 3982 patients received cardiac evaluation including echocardiography studies. 1830 (46.0%) pathologic findings were described, out of these 1371 (74.9%) patients had CHD, whereas 459 (25.1%) presented with AHD.

53.9% of the patients with CHD were female and the most common associated syndrome was Down syndrome in 12.8% of patients. In 807 patients (58.9%) diagnosis of CHD was established within the first year of life. The majority of patients (60.1%) were in need of surgical or interventional therapy at time of diagnosis and 6.3% of patients were judged inoperable at the time of first presentation. Nearly 50% of cases with AHD were rheumatic heart diseases followed by dilated cardiomyopathy and pulmonary hypertension without underlying CHD.Conclusions

The spectrum of CHD and AHD from one centre in Tanzania is comparable to findings reported in other countries from the African continent. Echocardiography is a valuable diagnostic tool and the widespread use of it should be enhanced to diagnose heart diseases in a large number and reasonable time. Most patients present late and majority is in need of surgical or interventional treatment, which is still not readily available. Untreated heart diseases contribute substantially to morbidity and mortality during infancy and childhood. Adequate cardiac services should be established and strengthened.
Potential application of Hibiscus sabdariffa L. (Malvaceae) and Lawsonia inermis L. (Lythraceae) aqueous extracts for assessment of viability of protoscolices from hydatid cysts
Authors: ELOWNI ELSAYED ELSIDDIG , Abdelnabi Ghada Hassan , AhmaD Mohamad Fadl , Badawi Reem Mustafa 
Published: August 2019

Abstract
Background

A number of commercial stains have been used to assess the viability of protoscolices ( defined as the capacity of being alive ) that develop in hydatid cysts, the infective stage of the tapeworm Echinococcus granulosus (s.l). There has been a remarkable increase of interest in natural product research over the past few decades for application of these products in a diversity of fields. Hibiscus sabdariffa L. (Malvaceae) is a flowering plant widely cultivated in the Sudan. Aqueous extracts from plant calyces have characteristic brilliant red colouration due to the presence of anthocyanins, an important group of water-soluble plant pigments. Lawsonia inermis L. (Lythraceae), commonly called "Henna" or "Mehndi ", is famous for having dyeing properties due to the presence of lawsone, a red-orange pigment extracted from plant leaves. Objective was to assess the viability of protoscolices of camel origin following exposure to aqueous extracts of H. sabdariffa calyces or L. inermis leaves taking advantage of the kinetically distinct molecular transfer systems of the Echinococcus protoscolex for uptake of materials across the tegument (external body covering).Results

Viable protoscolices are capable of exclusion of plant pigment obtained from either H. sabdariffa or L. inermis whereas dead protoscolices uptake the pigment in both occasions. Performance is comparable to eosin.Conclusions

It is suggested that extracts of both plants can be used effectively as a cheap and a readily available natural material for assessment of viability of protoscolices. Regarding the remarkable diversity of functions of the tapeworm tegument, it is proposed that the Echinococcus protoscolex can be employed as an experimental model in studies concerned with tapeworm natural protective responses in hostile environments, for instance upon exposure to antiparasitic drugs or host's body defences.
Hernia reduction following laparotomy using small stitch abdominal wall closure with and without mesh augmentation (the HULC trial, DRKS00017517): Study protocol for a randomized controlled trial
Authors: Heger Patrick , Feißt Manuel , Krisam Johannes , Klose Christina , Dörr-Harim Colette , Tenckhoff Solveig , Büchler Markus W. , Diener Markus K. , Mihaljevic Andre 
Published: August 2019

Abstract
Background Incisional hernias are among the most frequent complications following abdominal surgery and cause substantial morbidity, impaired health-related quality of life and costs. Despite improvements in abdominal wall closure techniques incisional hernia rates are reported to be between 10-30% following midline laparotomies. There have been two recent innovations with promising results to reduce hernia rates, namely the small stitches technique and the placement of a prophylactic mesh. So far, these two techniques have not been evaluated in combination.Methods The HULC trial is a multicentre randomized controlled, observer and patient blinded surgical effectiveness trial with two parallel study groups. A total of 812 patients scheduled for elective abdominal surgery via a midline laparotomy will be randomized in 12 centres after informed consent. Patients will be randomly assigned to the control group receiving closure of the midline incision with a slowly absorbable monofilament suture in small stitches technique or to the intervention group that will receive a small stitches closure followed by augmentation with a light-weight polypropylen mesh in onlay technique. The primary endpoint will be the occurrence of incisional hernias as defined by the European Hernia Society within 24 months after surgery. Further perioperative parameters, as well as patient-reported outcomes, will be analysed as secondary outcomes.Discussion The HULC trial will address the yet unanswered question whether a combination of small stitched fascial closure and onlay mesh augmentation after elective midline laparotomies reduces the rate of incisional hernias. The HULC trial marks the logical and innovative next step in the development of a safe abdominal closure technique.
A Novel Peer Mentor Model for Nutrition Education within a Food Pantry
Authors: Oliver Tracy Lynn , McKeever Amy , Shenkman Rebecca , Diewald Lisa K. 
Published: August 2019

Abstract
Background: Food insecurity disproportionately affects groups of Americans and is a social determinant of health that deems one at risk for comorbidities. Food insecurity is defined as reduced access to a sufficient quantity and quality of food, which limits the variety or desirability of one’s diet. Unfortunately, this hidden and silent epidemic in the United States continues to rise and is at an all-time high rate, with one in six children being affected, 13 million children and a total of 41.2 million Americans. As a result, emergency food pantries (EFPs) are challenged with the dual role of providing food to combat hunger, but also being conscious of the health concerns of their clients such as chronic illness and obesity. Methods: “Community Cooks” was a peer mentor model program implemented to deliver nutrition education, skills in basic cooking techniques, healthy eating principles, and easily prepared recipes relying on foods available within an EFP. Eleven peer mentors were recruited and trained over six months to deliver a series of live workshops open to all community members. Results: After six months, peer mentor retention rate was 85%, and qualitative focus group findings suggest that peer mentors had the desire to remain part of “Community Cooks” program. Conclusion: The use of a peer mentor model of delivering nutrition education within an EFP is a valuable and sustainable approach to target the food insecure and underserved population.