bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tourism information technology research trends: 1990-2016
Authors: Yuan Yulan , Tseng Yuen-Hsien , Ho Chaang-Iuan 
Published: August 2018

Purpose
The advancement of data analysis tools makes analyzing a huge amount of literature possible. This paper aims to identify tourism information technology research trends with the assistance of Toolkit for Academic Research (CATAR) to answer two research questions: the status of tourism information technology (IT) articles published in these selected journals from 1990 to 2016, and whether the number of Tourism IT articles is increasing or decreasing, and the main research topics studied in these articles from 1990 to 2016, and whether those have shifted over the 27 years.

Design/methodology/approach
Selected keywords identified by researchers that were used to extract Tourism IT articles published in Web of Science database. CATAR was used to carry out two analyses, namely, overview analysis and breakdown analysis. Overview analysis is performed to apply citation analysis to identify the general trend and the most cited reference of Tourism IT research represented by the selected articles. Breakdown analysis is based on bibliographic coupling (BC) analysis.

Findings
The number of Tourism IT publications grew rapidly in the second half of the 2000s, as mobile phones with touch screens became increasingly popular. It signals changes in the way of information searching behaviors. A total of 769 authors from 44 countries contributed to Tourism IT research. The USA, China, UK and Australia are the countries contributing the most. Six subject areas were revealed, namely, the interaction of people and organization; interaction of people and information; interaction of people and technology; technological implementation; the interaction of organization and information; and interaction of organization and technology.

Research limitations/implications
The major limitation of this study must be considered – the use of data merely derived from WoS database. The BC analysis makes a comparison between references of the given articles. This analysis requires the citation sources with better data quality, which is mainly based on the accuracy and standardization of databases. WoS is the database currently fit this requirement. The emergence of the new citation tools will enable scholars to pull data from new databases and to clean the data. Incorporating data from those new databases will reveal more accurate and comprehensive picture of Tourism IT research trend.

Originality/value
This paper revealed the research trend and major research subject areas of Tourism IT research for the past 16 years. The results can assist scholars to quickly grasp the Tourism IT research. This paper also provides an alternative approach to conduct literature review with computer-assisted analysis program.
Frequency dependence of pollinator visitation rates suggests that pollination niches can allow plant species coexistence
Authors: Benadi Gita , Pauw Anton 
Published: August 2018

AbstractHow do many species coexist within a trophic level? Resource niches are the classical answer, but in plants which share a small set of abiotic resources, the possibilities for resource partitioning are limited. One possible explanation is that plant species have different pollination niches, with each species specialized to a subset of the available animal species. If this pollinator partitioning results in negative frequency dependence such that each plant species’ reproduction is reduced when it becomes abundant, pollination niches could maintain plant diversity, provided that the strength of negative frequency dependence is sufficient to overcome fitness inequalities between species.We tested this idea by quantifying the effect of species relative abundance on pollinator visitation rate in a 7,000 m2plot of South African Fynbos vegetation. In addition, we quantified the effect of intraspecific abundance variation at a smaller spatial scale (9 m2plots), documented species’ pollination niches, and tested the importance of pollinators for seed set in a subset of the plant species.We found that visitation rate indeed declined sharply across the 33 plant species with increasing abundance, but visitation rate was also somewhat depressed in very rare species such that the resulting relationship between visitation rate and relative abundance was hump‐shaped. Pollinator niche partitioning among plant species was evident, but less pronounced than in many other studies. Visitation rate was slightly higher in more generalized species, suggesting that they have access to a larger pollination resource. At the intraspecific level and smaller spatial scale, results were less clear and varied among species. Pollinators enhanced seed set in most species.Synthesis. The results imply that, above an abundance threshold, intraspecific competition for pollination could limit the reproduction of common species, thus promoting plant species coexistence. However, the rarest plant species could become extinct due to pollen limitation, that is, an Allee effect. In addition, interactions with pollinators may introduce frequency‐independent fitness differences between plant species, thereby increasing the strength of negative frequency dependence required for stable coexistence. These findings shed new light on the role of the pollination niche in plant coexistence.
Lubrication during root canal treatment
Authors: Chandler Nicholas , Chellappa Deepak 
Published: August 2018

AbstractLubrication is involved in all root canal treatment phases, from dental dam placement to canal obturation. Most often associated with instrumentation, lubrication is required to facilitate the mechanical action of hand/rotary files and to help emulsify and suspend the debris produced. Aqueous irrigation solutions such as sodium hypochlorite and ethylenediaminetetraacetic acid (EDTA) should be regarded as lubricants, but paste‐type substances are marketed specifically for this purpose. As more patients demand the retention of challenging teeth with narrow and curved root canals, the importance of lubrication in all aspects of root canal treatment must be acknowledged.
Post‐treatment apical periodontitis related to the technical quality of root fillings and restorations in Thai population
Authors: Thampibul Panupong , Jantarat Jeeraphat , Arayasantiparb Raweewan 
Published: August 2018

AbstractThe aim of this study was to investigate the post‐treatment apical periodontitis in endodontically treated teeth related to the technical quality of root fillings and restorations in Thai population. Full‐mouth periapical radiographs from Thai patients attending the Faculty of Dentistry, Mahidol University, Thailand were examined. The periapical status, quality of root fillings and coronal restorations, existence of intraradicular post and its relationship to the root fillings were evaluated. Among 1586 patients, 37.4% presented endodontically treated teeth. The total number of endodontically treated teeth was 1511, and 35% presented apical periodontitis. Combined data for root filling and coronal restoration qualities revealed significantly better outcome in teeth with adequate qualities of both parameters than the other combinations (P < 0.001). The prevalence of post‐treatment apical periodontitis among Thai population was relatively high and significantly associated with substandard technical quality of root fillings and restorations.
Effect of different protocols of eugenol removal on the bond strength between the fibre post and root dentin
Authors: de Oliveira Emanuele , Cecchin Doglas , Miyagaki Daniela C. , de Moura Ana L. C. , Disarz Alana , Souza Matheus A. , Farina Ana P. 
Published: August 2018

AbstractThe aim of this study was to evaluate the bond strength between the fibre post and root dentin after different cleaning protocols to remove eugenol from dentin. The residues and elemental composition of dentin were analysed using SEM and EDS. Bovine incisor roots were obturated with eugenol‐based sealer. The post space was prepared, and the roots were divided into the following groups according to the cleaning protocol: unfilled (negative control), saline solution (positive control), 70% ethanol, acetone and 70% isopropyl alcohol. The fibre posts were cemented and push‐out test realised. Chemical analysis of the dentin was performed using SEM and EDS. The bond strength values were analysed by anova/Fisher's and were as follows: negative control (7.30 ± 2.77) = 70% ethanol (6.64 ± 2.91) = 70% isopropyl alcohol (5.01 ± 3.15) = acetone (4.42 ± 1.53) >positive control (1.29 ± 0.56). It was concluded that 70% ethanol may be a good cleaning protocol to remove eugenol from dentin.
Is infertility a disease and does it matter?
Authors: Maung Hane Htut 
Published: August 2018

AbstractClaims about whether or not infertility is a disease are sometimes invoked to defend or criticize the provision of state‐funded treatment for infertility. In this paper, I suggest that this strategy is problematic. By exploring infertility through key approaches to disease in the philosophy of medicine, I show that there are deep theoretical disagreements regarding what subtypes of infertility qualify as diseases. Given that infertility’s disease status remains unclear, one cannot uncontroversially justify or undermine its claim to medical treatment by claiming that it is or is not a disease. Instead of focusing on disease status, a preferable strategy to approach the debate about state‐funded treatment is to explicitly address the specific ethical considerations raised by infertility. I show how this alternative strategy can be supported by a recent theoretical framework in the philosophy of medicine which avoids the problems associated with the concepts of health and disease.
An ecological approach to modeling disability
Authors: Nathan Marco J. , Brown Jeffrey M. 
Published: August 2018

AbstractThis article develops an analysis of disability according to which disabling conditions are properties of organisms embedded in sets of environments. We begin by presenting the three mainstream accounts of disability—the medical, social, and interactionist models—and rehearsing some known limitations. We argue that, because of their primary focus on etiology, all three models share, more or less implicitly, a problematic assumption. This is the tenet that disabilities are individual properties. The second part of the essay presents an “ecological” interpretation of disability, inspired by classic and contemporary research on biological niches. Our proposal preserves many insights underlying extant approaches, while allowing a more accurate characterization of the nature and experience of disability. We conclude by drawing some general implications of our analysis.
Knowledge and degree of training of primary education teachers in relation to ICT taught to students with disabilities
Authors: Fernández‐Batanero José María , Cabero Julio , López Eloy 
Published: August 2018

AbstractThe integration of Information and Communication Technologies (ICT) into the inclusive classroom requires competent teaching staff from both the technological and pedagogical points of view. Within this context, and with the aim of looking at one of these theoretical premises, this study aimed to identify the degree of training and technological knowledge of primary school teachers in Spain with respect to the use of ICT with individuals with disabilities (functional diversity). A descriptive ex post‐facto research method was used, where the sample comprised 777 teachers. An ad‐hoc questionnaire was used as the data‐collection instrument. The results revealed the low skill levels of the teachers with respect to the use of ICT with students with disabilities, where the level of training of the teaching staff was determined by personal (gender, age), professional (teaching experience) or educational (qualifications) variables. The findings of this study point to the need for teacher training that instructs teachers on the use of ICT in order to favour the learning and educational innovation of students with disabilities.
Costimulatory checkpoint SLAMF8 is an independent prognosis factor in glioma
Authors: Zou Cun‐Yi , Guan Ge‐Fei , Zhu Chen , Liu Tian‐Qi , Guo Qing , Cheng Wen , Wu An‐Hua 
Published: August 2018

AbstractAimsImmune checkpoint blockade has made breakthroughs in immunotherapy for glioma. However, current immunotherapy has therapeutic benefits only in a subset of patients and accompanied by immune‐related side effects. SLAMF8 is a costimulatory molecule that affects the activation of macrophages in inflammation. The study of SLAMF8 may provide new information for immunological research and treatment of glioma.MethodsCGGA and TCGA cohorts of 946 patients with RNA sequencing data and full clinical information were analyzed using R language and GraphPad Prism 7.ResultsSLAMF8 was overexpressed along with malignancy progression and was a biomarker of mesenchymal subtype. As an independent prognostic factor, high SLAMF8 conferred reduced overall survival and chemotherapy resistance. SLAMF8 implied lower proportion of cancer cells along with increasing enrichment of monocytic lineage, myeloid dendritic cells. Functional analysis showed higher SLAMF8 indicated activation of antigen processing and presenting and the IFN‐γ/TNF/TLR‐mediated signaling. Meanwhile, coexpressing with classical checkpoint SLAMF8 aggravated immunosuppression and enhanced inflammation response.ConclusionOur study highlighted the important role of SLAMF8 in malignancy progression, shortened survival, and immune disorders. Further research on SLAMF8 in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.
Adolescent bariatric surgery: a qualitative exploratory study of US patient perspectives
Authors: Childerhose J. E. , Eneli I. , Steele K. E. 
Published: August 2018

SummaryBariatric surgery is a safe and effective intervention to treat severe obesity and related comorbidities in adolescents. No qualitative studies have explored the perspectives of US adolescent weight‐loss patients on their bariatric surgery motivations, decision‐making or experiences. The purpose of this qualitative exploratory study was to explore the perspectives of adolescent patients seeking bariatric surgery while enrolled in a medical weight management programme. Eligible participants 13–21 years old were recruited through a weight management programme at a tertiary care children's hospital in the US Midwest. Interviews were conducted remotely using a video chat medium. An initial 60‐min semi‐structured interview was conducted with seven participants who were 16–21 years old: one deciding on bariatric surgery, one pre‐operative and five post‐operative. A brief follow‐up interview was conducted 1 month later with four participants. Interviews were transcribed and coded using Atlas.ti software. Three broad themes emerged from participants’ reflections: the long journey to surgery, time scarcity and be ready for change. The decision to pursue bariatric surgery takes place after struggling with obesity and failed weight‐loss attempts since early childhood. Post‐operative participants described bariatric surgery as life‐changing, but determining when to schedule surgery is a challenge for adolescents.
Sclerosing odontogenic carcinoma in the mandible of a horse
Authors: Barceló Oliver F. , Kelly P. , Sharpe S. J. , Ayoub A. , Patterson‐Kane J. C. , Pollock P. J. 
Published: August 2018

SummaryA 15‐year‐old Cob mare was presented for investigation of a mandibular mass. Radiography identified an oval‐shaped mass occupying the intramandibular space, with a heterogeneous osseous opacity throughout the left hemimandible. Histopathology combined with immunohistochemistry was consistent with a diagnosis of sclerosing odontogenic carcinoma, which to date has only been described, rarely, in human patients. The mass was removed using a mandibular‐sparing surgical technique allowing preservation of the dental arcade. Follow‐up 5 years after surgery confirmed no signs of regrowth. This case report describes the successful treatment of a previously unreported mandibular neoplasm in the horse.
Venographic evaluation of the circumflex vessels and lamellar circumflex junction in laminitic horses
Authors: Kramer J. , Rucker A. , Leise B. 
Published: August 2018

SummaryVenograms provide information about areas of vascular compression or damage within the hoof. Key areas of the venogram to evaluate include the circumflex vessels, papillae and lamellar circumflex junction. This article describes and illustrates the appearance of the circumflex vessels, papillae and lamellar circumflex junction in sound and laminitic horses.
PPIENSENLo: A Novel Mnemonics in Spanish for Alarm Criteria in Secondary Headaches in Children
Authors: Marfil Alejandro , DeLaGarza‐Pineda Oscar , Barrera‐Barrera Silvia A. 
Published: August 2018

AbstractWe present the first mnemonic in Spanish, “PPIENSENLo,” for alarm criteria in secondary headaches in children in order to facilitate their identification, diagnosis, and treatment. A search was performed across different electronic databases for a mnemonics that applied to clinical alarm criteria in secondary headaches in children. None were found in English or Spanish. This tool is perhaps useful both for clinical and teaching purposes.
Pathogenic genes related to the progression of actinic keratoses to cutaneous squamous cell carcinoma
Authors: Zhang Lianbo , Qin Haiyan , Wu Zhuoxia , Chen Wanying , Zhang Guang 
Published: August 2018

AbstractBackgroundActinic keratosis (AK) is an incipient form of cutaneous squamous cell carcinoma (cSCC). Understanding the differentially expressed genes between AK and cSCC states would be helpful for the early prevention and treatment of cSCC. Consequently, this study aimed to screen the key genes associated with the progression of AK to cSCC.MethodsThe microarray dataset GSE45216 was downloaded from the Gene Expression Omnibus, which included 10 AK and 30 primary cSCC skin tissue samples. Differentially expressed genes (DEGs) in cSCC samples, compared to those in AK, were identified. Gene co‐expression relationships were investigated, followed by miRNA prediction. The potential functions of the co‐expressed genes were predicted by gene ontology (GO) and pathway enrichment analyses. In addition, the transcription factors and drug molecules, significantly related to the co‐expressed genes, were obtained.ResultsA total of 320 DEGs were identified in the cSCC group, relative to the AK group. Moreover, 96 DEGs and 2,390 connecting edges were identified in the gene co‐expression network. An miRNA regulatory network was constructed, including 96 DEGs and 16 miRNAs. In addition, three co‐expression network modules were obtained; EIF4EBP1, SNX17, PRPF4, NXT1, and UBA5 were significant nodes in the modules.ConclusionsEIF4EBP1, SNX17, PRPF4, NXT1, and UBA5 may be the pathogenic genes contributing to the development of cSCC from AK.
Combining microneedling with other minimally invasive procedures for facial rejuvenation: a split‐face comparative study
Authors: El‐Domyati Moetaz , Abdel‐Wahab Hossam , Hossam Aliaa 
Published: August 2018

AbstractBackgroundThe introduction of minimally invasive procedures has increased acceptance due to their efficacy, safety, and relatively long‐lasting and natural results. At least two different and unrelated modalities are employed to consider a combination treatment.ObjectivesThis study aims to evaluate and compare the use and effectiveness of combined microneedling with platelet‐rich plasma (PRP) or trichloroacetic acid (TCA) peeling for facial rejuvenation.Patients/methodsTwenty‐four volunteers with photoaging were randomly divided into three equal groups according to performed procedure on each side of the face (microneedling by dermaroller alone or combined with PRP or TCA 15% peeling). They had received one session every 2 weeks for six sessions of treatment. Photography and punch biopsies were performed before and after 3 months of treatment for clinical, histometrical, and histological evaluation.ResultsCombined treatment of dermaroller and PRP or dermaroller and TCA showed significant improvement when compared with dermaroller alone. Significant increase in epidermal thickness was apparent in studied groups, especially after combined treatment with TCA. Organized collagen bundles with newly formed collagen formation and markedly decreased abnormal elastic fibers were noticed in the three studied groups. However, improvement of dermal structures was better demonstrated after combined treatment of Dermaroller and PRP than Dermaroller and TCA 15%.ConclusionsMost volunteers showed significant clinical improvement after treatment supported by the histometrical and histochemical evaluation; however, the combined use of dermaroller with PRP is apparently more beneficial for facial rejuvenation.
Live remote digital microscopy in peripheral blood smear evaluation: Intraobserver concordance and experience
Authors: Haninger Diana M. , Nassiri Mehdi , Settembre Elizabeth D. , Zhang Shanxiang , Zhou Jiehao 
Published: August 2018

AbstractIntroductionPeripheral blood smear (PBS) review is a routine laboratory test which requires pathologist's interpretation when abnormal indices, atypical cells, or critical findings are identified. Real‐time remote digital microscopy (DM) can potentially facilitate rapid review when an on‐site pathologist is not available. Herein, we assess intraobserver concordance of PBS evaluation with light microscopy (LM) and DM using VisionTek M6 robotic DM and TeamViewer imaging software.MethodsThirty‐seven de‐identified PBS slides were evaluated by five reviewers. Slides were loaded on a VisionTek M6 robotic microscope at an off‐site laboratory and evaluated remotely via TeamViewer software. Reviewers recorded interpretation, time required for interpretation (in minutes), imaging quality (score 0‐3), and confidence of interpretation (score 0‐3). Other relevant information associated with DM evaluation was also documented. Slides were subsequently evaluated using LM after washout interval. The intraobserver variation of results for impression, digital slide quality, minutes to interpretation, and confidence of interpretation was compared between DM and LM.ResultsThe intraobserver concordance between LM and DM was 93%, with nine discordant interpretations among 135 evaluations under each review modality, respectively. Although reviewers spent more time under DM mode (5 min/slide) than LM mode (2.5 min/slide), the reviewers felt the DM provided sufficient image quality and the confidence levels of reviewers on slide interpretation were comparable between DM (2.6/3) and LM (2.8/3).ConclusionThere was a high level of intraobserver concordance and comparable interpretation confidence between DM and LM. DM can be a useful methodology for off‐site pathologist's review of PBS.