bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Komparatif Obesitas dan Non-Obesitas Berdasarkan Asupan Junk Food di SMA Tarakanita Gading Serpong
Authors: Teguh Stanislas Kotska Marvel Mayello , Santoso Alexander Halim 
Published: November 2024

ABSTRACT The prevalence of obesity among adolescents is increasing. One major factor is the consumption of junk food. The ease of serving, variety, better taste, and marketing make teenagers prefer to consume junk food rather than foods that contain healthy nutrition. The purpose of this study was to determine the comparison between obese and non-obese students on junk food consumption at Tarakanita Gading Serpong senior high school. This study is a cross-sectional study with a total of 162 students. Students were asked to fill out a questionnaire related to junk food consumption and take measurements of body weight and height. The results of these measurements were mapped onto the CDC growth chart to obtain their nutritional status. There was a significant mean difference between obese and non-obese students in terms of junk food consumption (p<0.05). Students should be aware of the impact of junk food consumption on health through continuous education, provision of healthy canteens in schools, and increased sports activities. Keywords: Junk Food, Obesity, Body Mass Index, Senior High School ABSTRAK Prevalensi obesitas di kalangan remaja semakin meningkat. Salah satu faktor yang berperan berperan besar adalah konsumsi junk food. Kemudahan dalam penyajian, variasi, rasa yang lebih enak rasa, dan pemasarannya membuat remaja lebih memilih untuk mengonsumsi junk food daripada makanan yang mengandung gizi sehat. Tujuan dari penelitian ini adalah untuk mengetahui perbandingan antara siswa obesitas dan non obesitas terhadap konsumsi junk food di SMA Tarakanita Gading Serpong. Penelitian ini merupakan penelitian potong lintang dengan jumlah siswa 162 orang. Siswa diminta untuk mengisi kuesioner terkait konsumsi junk food dan melakukan pengukuran berat badan dan tinggi badan. Hasil dari pengukuran tersebut dipetakan ke dalam grafik pertumbuhan dari CDC untuk didapatkan status gizinya. Terdapat perbedaan rerata yang signifikan antara siswa yang mengalami obesitas dan tidak mengalami obesitas berdasarkan konsumsi junk food (p<0,05). Kesadaran akan dampak konsumsi junk food terhadap kesehatan harus lebih ditingkatkan di kalangan siswa melalui edukasi berkesinambungan, pengadaan kantin sehat di sekolah, serta peningkatan kegiatan olahraga. Kata Kunci: Junk Food, Obesitas, Indeks Masa Tubuh, SMA
Hubungan Tekanan Darah, Frekuensi Nadi dan Konsumsi Kopi dengan Fokus pada Mahasiswa Kedokteran Universitas Tarumanagara Angkatan 2021
Authors: Putra Muhammad Dzakwan Dwi , Lontoh Susy Olivia 
Published: November 2024

ABSTRACT Coffee is one of the most widely consumed beverages in the world. According to data from the International Coffee Organization (ICO), global coffee consumption reached 166.35 million bags/60 kg in the 2020/2021 period. Indonesia is in fifth place with coffee consumption of 5 million bags/60 kg. Medical and health science students have a higher study load, so they consume coffee for study purposes. Caffeine, the active ingredient in coffee, has been shown to have pharmacological effects on the cardiovascular system and stimulates the central nervous system, thereby increasing heart rate and blood pressure. The purpose of this study was to determine the effect of caffeinated beverages, especially coffee, on blood vessels and heart rate of young adults, with a focus on medical students of Tarumanagara University, class of 2021. This study used an experimental-based research design with a pre-test/post-test comparison technique. The total number of participants was 56 respondents with an age range between 19 and 22 years. In this study, the data analysis method used a paired sample t-test. After drinking coffee for 5, 10, or 1 minutes, the results showed an increase in blood pressure and heart rate (p < 0.05). Caffeinated beverages, especially coffee, can increase blood pressure and heart rate. Keywords: Coffee Consumption, Blood Pressure, and Heart Rate ABSTRAK Kopi merupakan salah satu minuman yang paling banyak dikonsumsi di dunia. Menurut data International Coffee Organization (ICO), konsumsi kopi secara global mencapai 166,35 juta karung/60 kg pada periode 2020/2021. Indonesia berada di posisi kelima dengan konsumsi kopi sebanyak 5 juta karung/60 kg. Mahasiswa kedokteran dan ilmu kesehatan memiliki beban kuliah yang lebih tinggi, sehingga mereka mengonsumsi kopi dengan tujuan belajar. Kafein, bahan aktif dalam kopi, terbukti memiliki efek farmakologis pada sistem kardiovaskular dan menstimulasi sistem saraf pusat, sehingga dapat meningkatkan frekuensi nadi dan tekanan darah. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh minuman berkafein khususnya kopi terhadap pembuluh darah dan frekuensi denyut nadi dewasa muda, dengan fokus pada mahasiswa kedokteran Universitas Tarumanagara angkatan 2021. Penelitian ini menggunakan desain penelitian berbasis eksperimental dengan teknik membandingkan pre-test/post-test. Jumlah partisipan seluruhnya adalah 56 responden dengan rentang usia antara 19 hingga 22 tahun. Dalam penelitian ini metode analisis data menggunakan uji beda berpasangan (paired sample t-test). Setelah minum kopi selama lima, sepuluh, atau lima belas menit, hasilnya menunjukkan peningkatan tekanan darah dan frekuensi nadi (p < 0,05). Minuman yang mengandung kafein, khususnya kopi, dapat meningkatkan tekanan darah dan denyut nadi. Kata Kunci: Konsumsi Kopi, Tekanan Darah, dan Frekuensi Nadi
Pengaruh Latihan dan Indeks Massa Tubuh terhadap Kapasitas Vital Angkatan pada Mahasiswa Kedokteran Universitas Tarumanagara
Authors: Raharjo Anthony Jason , Lontoh Susy Olivia 
Published: November 2024

ABSTRACT Healthy lungs are those that function well as respiratory organs and provide oxygen to the entire body. Exercise is one of the factors that play an important role in lung function. This study aims to determine the relationship between exercise, BMI, and lung function, including forced vital capacity (FVC), among medical students at Tarumanagara University. This research employs a cross-sectional design and an analytical observational study with 75 students who underwent spirometry tests and completed questionnaires related to their exercise habits. The results indicate that exercising at least once a week correlates with a significant increase in FVC, with a p-value of 0.005 (p < 0.05). However, the p-value for nutritional status and FVC is 0.802, indicating no significant relationship (p > 0.05). Readers of this study should consider engaging in regular exercise, as the findings suggest that exercise can positively impact the body. In conclusion, there is a relationship between exercise and forced vital capacity, whereas there is no relationship between nutrition based on BMI and forced vital capacity. Keywords: Exercise, Body Mass Index, Lung Function, Force Vital Capacity ABSTRAK Paru-paru yang sehat adalah paru-paru yang dapat berfungsi dengan baik sebagai organ pernafasan dan memberikan oksigen ke seluruh tubuh. Olahraga merupakan salah satu faktor yang berperan penting dalam fungsi paru-paru. Penelitian ini bertujuan untuk mengetahui hubungan antara olahraga dengan IMT dan fungsi paru termasuk kapasitas vital paksa (KVP) pada mahasiswa Fakultas Kedokteran Universitas Tarumanagara. Jenis penelitian ini menggunakan desain cross-sectional dan studi observasional analitik terhadap 75 siswa yang menjalani tes spirometri dan mengisi kuesioner terkait kebiasaan olahraganya. Hasil penelitian menunjukkan bahwa berolahraga minimal seminggu sekali berkorelasi dengan peningkatan FVC yang signifikan dengan p-value = 0,005 (p < 0,05). Sedangkan nilai p-value = 0,802 berarti p<0,05 untuk status gizi dan KVP. Pembaca penelitian ini sebaiknya mempertimbangkan untuk melakukan olahraga karena hasil penelitian ini menunjukkan bahwa olahraga dapat berdampak positif pada tubuh. Kesimpulannya terdapat hubungan antara olahraga dengan kapasitas vital paksa, sedangkan tidak ada hubungan antara gizi berdasarkan BMI dengan kapasitas vital paksa. Kata Kunci: Olahraga, Indeks Massa Tubuh, Fungsi Paru, Kapasitas Vital Paru
Penerapan Nilai Organisasi untuk Meningkatkan Motivasi dan Kinerja Perawat di Rumah Sakit; Literature Review
Authors: Yonna Catrolina , Suryani Maria 
Published: November 2024

ABSTRACT The tradition of hospital organizations are the values, norms, and action that shared between the members of the organization and it affect how they interact with each other. Organizational values can affect the motivations, commitments, loyality, inovation, creativity, and productivity of a nurse. To know the effects of organizational values on the motivations and performance of nurse in Hospital. Lliterature review using two database (ProQuest and Google Scholar) to search for journal article with publication criteria from 2021 – 2023. This research showed that organization does gave a significant effect to the motivations and performance of a nurse in the hospital and one article does said that the organizational tradition didn't affect nurses motivations and performance in the hospital. This research concluded that a condusive and comfortable organizational values will effect the motivation and performance of a nurse to achieve quality of the healthcare at the hospital Keywords: Organizational Values, Work Motivation, Nurse Performance ABSTRAK Budaya organisasi rumah sakit adalah nilai-nilai, norma dan perilaku yang dibagikan oleh para anggota organisasi dan mempengaruhi cara berinteraksi dengan satu sama lain. Nilai organisasi dapat mempengaruhi motivasi, komitmen, loyalitas, inovasi, kreativitas dan produktivitas seorang perawat. Mengetahui pengaruh nilai organisasi terhadap motivasi dan kinerja perawat di Rumah Sakit. Tinjauan literatur dengan menggunakan 2 database (ProQuest dan Google Scholar) untuk mencari artikel jurnal dengan kriteria publikasi 2021-2023. Penelitian ini menunjukkan bahwa organisasi sangat berbengaruh yang signifikan terhadap motivasi dan kinerja seorang perawat di rumah sakit dan satu artikel juga mengatakan bahwa budaya organisasi tidak berpengaruh terhadap kinerja perawat di rumah sakit. Penelitian ini menyimpulkan bahwa nilai organisasi yang kondusif dan nyaman akan mempengaruhi motivasi dan kinerja seorang perawat dalam pelayanan kesehatan yang bermutu dan berkualitas di rumah sakit. Kata Kunci: Nilai Organisasi, Motivasi, Kinerja Perawat
Preparing educators for the digital age: teacher perceptions of active teaching methods and digital integration
Authors: Abildinova Gulmira , Abdykerimova Elmira , Assainova Almagul , Mukhtarkyzy Kaussar , Abykenova Dariya 
Published: November 2024

IntroductionThis study investigates higher education teachers’ perceptions of active teaching methods—Case-Based Learning (CBL), Problem-Based Learning (PBL), and Team-Based Learning (TBL)—and their integration with digital technologies. These pedagogical strategies are crucial for fostering critical thinking, collaboration, and problem-solving skills among students, especially in the digital age. Despite their benefits, challenges such as resource limitations, time constraints, and insufficient training hinder their implementation.MethodsA mixed-methods approach was adopted, involving 104 educators from various higher education institutions in Kazakhstan. Participants underwent an eight-week training program consisting of 72 h of workshops, collaborative activities, and self-paced learning. Pre- and post-training assessments measured knowledge, confidence, and practical application of active teaching methods. Surveys, feedback sessions, and peer evaluations provided qualitative and quantitative insights into participants’ experiences and challenges.ResultsThe training program significantly improved participants’ knowledge, confidence, and ability to implement CBL, PBL, and TBL. Post-training assessments showed a 4.2-point increase in confidence and practical application scores. Most educators (66.35%) reported moderate adaptability of these methods to their current educational programs, while 27.88% achieved high adaptability. Participants identified resource limitations (43.27%) and time constraints (33.65%) as key challenges. Problem-Based Learning (PBL) was preferred for fostering critical thinking and problem-solving, with a majority (51.92%) favoring it over other methods. Digital technologies, such as Moodle and augmented reality tools, enhanced teaching effectiveness and student engagement.DiscussionThe findings highlight the transformative potential of active teaching methods and digital integration in higher education. Educators across various academic positions and institutions perceived these methods as highly effective, aligning with the Diffusion of Innovations Theory. Challenges such as insufficient resources and curriculum misalignment were significant barriers to broader adoption. Continuous professional development, institutional support, and strategic resource allocation are crucial for optimizing these methods’ impact.
A critical analysis of the factors influencing peaceful coexistence between Rohingya refugees and host communities in Cox’s Bazar, Bangladesh
Authors: Khan Abdul Kadir 
Published: November 2024

IntroductionBangladesh currently hosts over a million Rohingya refugees in 33 fetid, dire, and confined camps, with the majority arriving after the 2017 military crackdown in Myanmar’s Rakhine state. Although Rohingya refugees have been arriving in Bangladesh since the 1970s, the mass influx following the 2017 military hostilities in Myanmar’s Rakhine State marked a significant crisis escalation. Initially, the local host communities displayed positive, sympathetic attitudes toward the refugees. However, recent evidence suggests a significant decline in social cohesion and peaceful coexistence, with host communities expressing diminished sympathy and growing concerns over the refugees’ prolonged presence in Cox’s Bazar.ObjectivesThis paper investigates the factors influencing the peaceful coexistence between Rohingya refugees and host communities, drawing on the perspectives of development and humanitarian service providers in the Ukhiya and Teknaf sub-districts of Cox’s Bazar.MethodsThe study utilized a mix of theoretical literature and empirical data to identify five determining factors: economic, social, political, cultural, and environmental. Data collection included 18 in-depth key informant interviews, supplemented by analyses of secondary sources drawn from both gray and academic literature.FindingsThe findings indicate that perceived outgroup threats are increasingly undermining peaceful coexistence, despite the absence of direct conflicts between the host and refugees. While political and cultural factors have remained relatively stable, social, economic, and environmental factors continue to erode the current status of peace.DiscussionThe study highlights spatial and psychological proximity as critical overarching factors in fostering peaceful coexistence. It concludes that closer proximity heightens integrated threats, whereas maintaining optimal distance enhances the likelihood of peaceful coexistence. Therefore, the Rohingya response plan should incorporate conflict-sensitive strategies to tackle the adversity of threat factors while maintaining social cohesion as promoting peaceful coexistence between hosts and refugees.
Hypoimmunogenic CD19 CAR-NK cells derived from embryonic stem cells suppress the progression of human B-cell malignancies in xenograft animals
Authors: Zhang Qi , Xia Chengxiang , Weng Qitong , Zhang Leqiang , Wang Yao , Liu Yanhong , Zheng Xiujuan , Lin Yunqing , Chen Yi , Shen Yiyuan , Qi Hanmeng , Liu Lijuan , Zhu Yanping , Zhang Min , Huang Dehao , Hu Fangxiao , Zhang Mengyun , Zeng Hui , Wang Jinyong , Wang Tongjie 
Published: November 2024

BackgroundChimeric antigen receptor (CAR) engineered natural killer (NK) cells exhibit advantages such as MHC-independent recognition and strong anti-tumor functions. However, allogeneic CAR-NK cells derived from human tissues are heterogeneous and susceptible to clearance by hosts.MethodsWe generated a B2M knockout, HLA-E and CD19 CAR ectopic expressing embryonic stem cell (ESC) line, which differentiated normally and gave rise to homogeneous CD19 CAR-NK (CD19 CAR-UiNK) cells using an organoid aggregate induction method. The CD19 CAR-UiNK were co-cultured with T cells or NK cells derived from peripheral blood mononuclear cells (PBMC) with the mismatched HLA to evaluate the immunogenicity of CD19 CAR-UiNK cells. We further assessed the therapeutic effects of CD19 CAR-UiNK cells on CD19+ tumor cells through in vitro cytotoxicity assays and in vivo animal models.ResultsThe CD19 CAR-UiNK cells exhibited typical expression patterns of activating and inhibitory receptors, and crucial effector molecules of NK cells, similar to those of unmodified NK cells. In co-culture assays, the CD19 CAR-UiNK cells evaded allogeneic T cell response and suppressed allogeneic NK cell response. Functionally, the CD19 CAR-UiNK cells robustly secreted IFN-γ and TNF-α, and upregulated CD107a upon stimulation with Nalm-6 tumor cells. The CD19 CAR-UiNK cells effectively eliminated CD19+ tumor cells in vitro, including B-cell cancer cell lines and primary tumor cells from human B-cell leukemia and lymphoma. Further, the CD19 CAR-UiNK cells exhibited strong anti-tumor activity in xenograft animals.ConclusionWe offer a strategy for deriving homogeneous and hypoimmunogenic CD19 CAR-iNK cells with robust anti-tumor effects from ESCs. Our study has significant implications for developing hypoimmunogenic CD19 CAR-NK cell therapy using human ESC as an unlimited cell source.
Transcutaneous electrical acupoint stimulation for upper limb motor recovery after stroke: a systematic review and meta-analysis
Authors: Wang Xiaoyu , Yin Lianjun , Wang Yikun , Zhang Haining , Zhang Shiying , Wu Jiantong , Fan Shun , Li Zhengfei , Li Huanan , Wang Jingui 
Published: November 2024

BackgroundTranscutaneous electrical acupoint stimulation (TEAS) is an innovative, non-invasive therapy that stimulates the contraction of paralyzed muscles in the upper limbs, promoting functional recovery. Several studies have demonstrated the efficacy of TEAS in restoring upper limb function. This study aims to evaluate the impact of TEAS on upper limb motor recovery after stroke.ObjectivesThis study aims to evaluate the influence of TEAS on upper limb motor recovery after stroke and improve the quality of life in such patients.MethodsEight databases were systematically searched from inception to 1st October 2024. Two independent reviewers conducted the screening and data extraction of the study. The primary outcome measure was the Fugl Meyer Assessment of the Upper Extremity (FMA-UE), which evaluates upper extremity motor function in stroke patients. Secondary outcomes included the Modified Ashworth Scale (MAS) for assessing spasticity and the Modified Barthel Index (MBI) to evaluate patients’ abilities to perform activities of daily living. Data synthesis was conducted using RevMan 5.4 and Stata 14.0. The GRADE method was employed to assess the quality of evidence.ResultsA total of 16 trials involving 1,218 stroke patients were included in this meta-analysis. Meta-analysis showed that the TEAS significantly improved upper limb function (SMD = 1.70, 95CI% = 1.09 to 2.31, p &lt; 0.00001, I2 = 93%; low certainty of evidence), reduced spasticity (SMD = −1.18, 95CI% = −1.79 to −0.58, p &lt; 0.00001, I2 = 90%; very low certainty of evidence), and enhanced the ability to perform daily activities (SMD = 1.53, 95CI% = 0.85 to 2.20, p &lt; 0.00001, I2 = 95%; low certainty of evidence).ConclusionOur results indicated that TEAS improved motor function and functional activities and reduced muscle tone in the upper limbs after stroke. However, these results should be interpreted with caution due to the limited strength of the evidence. High-quality, larger sample, multi-center studies are needed to validate these preliminary findings.Systematic review registrationThis study was registered on PROSPERO with registration number CRD42024592509. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024592509
A study of the correlation between sarcopenia and cognitive impairment in older individuals over 60 years: cross-sectional and longitudinal validation
Authors: Dong Xiaohan , Yu Yichao , Li Jiahao , Chai Xinyu , Shan Wei , Yan Huiping , Lu Yifan 
Published: November 2024

ObjectiveTo validate the correlation between sarcopenia and cognition, and explore cognitive subdomains affected by sarcopenia.MethodsA case–control study was designed to recruit 90 individuals aged 60 and above from June to October 2023 in the same community, all individuals meeting the inclusion criteria were categorized according to the 2019 Asian criteria for sarcopenia and divided into the sarcopenia group and non-sarcopenia group at baseline. After a 12-week follow-up recording, individuals were classified into the aggravation group and alleviation group based on the change of sarcopenia severity. Sarcopenia tests including muscle mass, calf circumference, grip strength and physical function assessment, using Montreal Cognitive Assessment (MoCA) of nine dimensions for cognitive assessment.Results(1) There was a significant positive correlation between cognitive function and grip strength in males (r = 0.42, p &lt; 0.05). (2) There was a moderate correlation between sarcopenia grading and MoCA score (r = −0.4, p &lt; 0.001). (3) Individuals with sarcopenia had significantly lower MoCA total scores and sub-scores in executive function, fluency, calculation and delayed recall compared to non-sarcopenia group (p &lt; 0.05). (4) After 12 weeks, the mean value of the change in fluency in the alleviation group increased by 0.33 points, while the aggravation group decreased by 0.2 points (W = 128, p &lt; 0.05).ConclusionThere is a correlation between sarcopenia and cognitive function, individuals with sarcopenia performing poorly in overall cognition as well as refined dimensions. The degree of cognition like fluency degenerates over time with increasing severity of sarcopenia.
Characterizing headache patients admitted from the emergency department: a retrospective study
Authors: AlGhamdi Faisal , Alzahrani Abdulelah A. , Alwatyan Khaleel I. , Hariri Reem A. , Alhowaish Abdullah A. , Almobarak Rahaf F. , Almulhim Mohammed , Alkhadra Faisal B. 
Published: November 2024

BackgroundHeadaches are a common complaint in emergency department (ED) presentations, but the demographics, clinical characteristics, and outcomes of patients admitted with headaches remain understudied. This retrospective study aims to investigate patients admitted with a chief complaint of headache.MethodsThe study examined the triage database of our ED from 01/01/2020 to 31/12/2022 to identify patients admitted to either the wards or intensive care unit (ICU) with headache as their primary complaint.ResultsOut of 347 identified patients, 100 met the inclusion criteria. The gender distribution was equal. The majority of cases (36%) were between 31 and 45 years old. Headache and dizziness were the most common complaints (54%), followed by chest pain (18%) and abdominal pain (10%). Neurological system involvement was observed in 60% of cases. Computed Tomography (CT) scans were performed in 87% of cases, while Magnetic Resonance Imaging (MRI) scans were done in 45% of cases. Comorbidities such as central nervous system (CNS) diseases (40%) and cardiovascular diseases (CVD) (36%) were prevalent. The average length of stay in the ED before admission was 35.3 h.ConclusionThis study provides insights into the demographics, clinical characteristics, and outcomes of patients admitted with headaches in the ED. The equal gender distribution and age distribution align with findings from other studies. The high utilization rate of CT scans suggests diagnostic uncertainty among emergency physicians. These findings contribute to the understanding of headache presentations in the ED and serve as a foundation for future research.