bluuebunny/crossref_metadata_2025_split huggingface dataset:
A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrheapredominant irritable bowel syndrome
Authors: Ishaque M.Sh. , Khosruzzaman S.M. , Ahmed D.S. , Sah M.P. 
Published: October 2018

Background: Accumulating evidence supports the view that an imbalance of gut bacteria contributes to IBS, and that increasing the mass of beneficial species may reduce the numbers of pathogenic bacteria and help alleviate symptoms.Methods: In this double-blind trial 400 adult patients with moderate-to-severe symptomatic diarrhea-predominant IBS (IBS-D) were randomized to treatment with the multi-strain probiotic Bio-Kult® (14 different bacterial strains) or placebo for 16 weeks. The change in severity and frequency of abdominal pain was the primary outcome measure.Results: Probiotic treatment significantly improved the severity of abdominal pain in patients with IBS-D. A 69% reduction for probiotic versus 47% for placebo (p < 0,001) equates to a 145 point reduction on the IBS-severity scoring system (IBS-SSS). The proportion of patients who rated their symptoms as moderate-to-severe was reduced from 100% at baseline to 14% for the multi-strain probiotic at follow-up (month 5) versus 48% for placebo (p < 0,001). Also, the number of bowel motions per day from month 2 onwards was significantly reduced in the probiotic group compared with the placebo group (p < 0,05). In addition to relieving symptoms, the probiotic markedly improved all dimensions of quality of life in the 34-item IBS-Quality of Life (IBS-QoL) questionnaire. No serious adverse events were reported.Conclusions: The multi-strain probiotic was associated with significant improvement in symptoms in patients with IBSD and was well-tolerated. These results suggest that probiotics confer a benefit in IBS-D patients which deserves further investigation. Trial registration: [Clinicaltrials.gov NCT03251625; retrospectively registered on August 9, 2017].
A participação dos países em desenvolvimento e menos desenvolvidos no Órgão de Solução de Controvérsias da Organização Mundial do Comércio
Authors: De Lucena Andréa Freire , De Carvalho Samuel Rufino 
Published: October 2018

O Órgão de Solução de Controvérsias da Organização Mundial do Comércio almeja solucionar as disputas comerciais dos países, por meio da supervisão, do monitoramento e da averiguação do cumprimento de suas regras. Um dos entraves do sistema diz respeito às dessemelhanças entre países desenvolvidos e em desenvolvimento. Este artigo investiga a existência de assimetrias de participação entre os países menos desenvolvidos (PMD), países em desenvolvimento (PED) e países desenvolvidos (PD) no âmbito do Órgão de Solução de Controvérsias, desde a sua criação em 1995 até o ano de 2016. Os dados coletados foram trabalhados pelo uso dos métodos estatístico e comparativo, com a intenção de se obter uma análise minuciosa acerca das disputas comerciais e verificar os níveis de desigualdade de atuação na instituição. Observou-se que o Órgão possui assimetrias evidentes de participação, que refletem a divisão internacional do trabalho presente no sistema internacional, em que os Estados de maiores rendas atuam mais facilmente com vistas a suprir suas demandas.
Paradiplomacia como Política Externa e Política Pública: modelo de análise aplicado ao caso da cidade do Rio de Janeiro
Authors: Mercher Leonardo , Pereira Alexsandro Eugenio 
Published: October 2018

O presente artigo argumenta que estudos de paradiplomacia devem se aproximar dos estudos de política externa quando investigada como política pública. Essa seria uma estratégia para análise das práticas e estratégias das cidades nas relações internacionais. Os rendimentos analíticos dessa estratégia podem ser observados por meio de um modelo dimensional de análise de paradiplomacia como política externa e política pública. Esse modelo é propostoneste artigo e aplicado ao estudo empírico da cidade do Rio de Janeiro, no período de 1993 até 2016. O modelo sugere cinco dimensões explicativas nas análises da paradiplomacia: gestão política; mercado; institucional; internacional; e epistêmica. A aplicação desse modelo à cidade do Rio de Janeiro permitiu identificar as dimensões mais relevantes no caso específico da cidade — as dimensões política e de mercado —, enquanto que a variável partidária,defendida por outros pesquisadores do campo como de alta capacidade explicativa, pouco interferiu nos resultados observados durante a pesquisa.
An assessment of the operational freeware management tools for multi-reservoir systems
Authors: Rozos Evangelos 
Published: October 2018

Abstract
Water resources management is one of the most challenging problems of the water sector. The complexity of this problem is mostly attributed to the dynamic nature of the natural hydrosystems, of which the inputs are characterized by stochasticity. The assessment of the impact of alternative decisions on such a system requires a probabilistic approach. It is evident that this is a very demanding task even for a single-reservoir system, not to mention multi-reservoir systems. For this reason, computer codes have been developed since the early 1970s to help with this procedure. Nowadays, these codes have evolved into decision support platforms that offer a user interface to assist the pre-processing and the post-processing. However, the majority of the available tools are commercial and require a considerable amount of money for a licence. Thankfully, a few freeware tools that are based on the simulation–optimization method and with a modern user interface exist. The objective of this study is to assess the performance of these freeware tools. The assessment is based both on an analysis of the theoretical basis and on an application of the models on a simplified representation of the Athens water supply system.
Structural and Molecular Tear Film Changes in Glaucoma
Authors: Mastropasqua Rodolfo , Agnifili Luca , Mastropasqua Leonardo 
Published: October 2018

:
The Tear Film (TF) is a trilaminar and dynamic fluid covering the entire Ocular
Surface (OS), consisting of a mucus, aqueous, and lipid layer deeply interacting between
them. Because of its structure and functions, TF plays a pivotal role in the preservation of the
OS integrity and the quality of vision. Medical therapy for glaucoma is recognized to profoundly
disturb the OS homeostasis by altering all components of the ocular surface unit, including
TF. The presence of preservatives, the number of daily eye drops instillations, and the
duration of therapy are the main contributors to TF changes. From the physio-pathological
side, TF alterations are induced by toxic and allergic mechanisms and result from goblet cell
and Meibomian gland loss, dysfunction of accessory lacrimal glands, and epithelial disruption.

:
In detail, TF changes are represented by mucus layer thinning, reduced mucin concentration,
aqueous layer volume reduction, and lipid layer thinning with increased tear evaporation. Hyper-
osmolarity and instability represent the main hallmarks of these changes and are an
expression of a iatrogenic form of dry eye. TF undergoes also molecular modifications that
primarily reflect a therapy- or disease-induced inflammatory status of the OS. Over the last
years, this field of research aimed a progressively growing interest since molecular variations
may be considered as potential candidate biomarkers of glaucoma. The aim of this review is
to report the main TF changes occurring during glaucoma, exploring the relationship they
may have with the glaucoma-related ocular surface disease and the patient quality of life, and
their utility as potential biomarkers of disease.
Torsion of Wandering Spleen: Importance of Splenic Density and Liver-to- Spleen Attenuation Ratio on CT
Authors: Cetinoglu Yusuf Kenan , Karasu Sebnem , Acar Turan , Uluc Muhsin Engin , Haciyanli Mehmet , Tosun Ozgur 
Published: October 2018

Background:
Wandering spleen (WS) is a rare clinical condition which may cause fatal
complication like torsion with subsequent infarction. Determination of splenic parenchyma viability
is very important in deciding whether splenopexy rather than splenectomy is an option. Contrast-
enhanced computed tomography (CECT) is important for the diagnosis of WS and assessment
of the viability of spleen.

Discussion:
We reviewed the CT studies of four cases with WS. We measured the mean splenic
and liver density and calculated liver-to-spleen attenuation ratio (LSAR). We also assessed the CT
findings for each patient. Mean splenic density was measured as 40.77 Hounsfield Unit (HU) in
cases with infarction, 127.1 HU in case without infarction. LSAR was calculated as 2.55 in cases
with infarction, 0.99 in case without infarction. We detected whirlpool sign, intraperitoneal free
fluid, splenic arterial enhancement in all patient, parenchymal and splenic vein enhancement in one
patient without infarction, fat rim sign in three patients with infarction, capsular rim sign in one patient
with infarction.

Conclusion:
CECT should be obtained for the diagnosis of WS and assessment of the viability of
spleen. CECT could suggest the diagnosis of infarction of the spleen with following findings; absence
of parenchymal enhancement, very low density of spleen (<45 HU), and LSAR which is
greater than 2.
FUNGSI ALGORITMA RSA UNTUK MEMODIFIKASI DAN MENINGKATKAN PENGAMANAN ACAKAN BISS
Authors: Gunawan Indra , Sumarno Sumarno , Tambunan Heru Satria 
Published: October 2018

AMIK dan STIKOM Tunas Bangsa yang memiliki keunggulan kompetitif merupakan jantung kinerja lembaga sebuah pendidikan dalam sebuah pasar yang kompetitif. Banyak faktor yang mempengaruhi keunggulan sebuah Akademi Ilmu Komputer. Faktor-faktor tersebut diantaranya merancang dan meningkatkan sebuah keamanan data. Pada saat ini, sudah begitu banyak media-media informasi, promosi, perfilman dan olah raga yang sangat berperan untuk memberikan suatu pengetahuan yang dapat mempengaruhi perubahan di masyarakat. Salah satu contoh media yang sangat berhasil tersebut untuk saat ini adalah media televisi. Dengan adanya media televisi yang dibarengi dengan keluarnya produk-produk digital-reciever yang digunakan untuk sarana penangkapan sinyal siaran melalui satelit, dapat menekankan bahwa media televisi benar-benar dapat dijadikan sebagai patokan untuk sarana penyampaian informasi karena sudah mengacu kepada audio dan visual yang dapat memperjelas suatu keadaan secara langsung. Didalam penyampaian informasinya, media televisi dapat melibatkan media-media yang lain seperti media massa, media cetak, media pendidikan, media olah raga, media perfilman dan media internet sehingga sangat cocok untuk digunakan sebagai media penyampaian informasi kepada masyarakat karena sudah mengacu kepada audio dan visual, yang sekarang ini biasa disebut dengan multimedia. Penelitian ini bertujuan untuk meningkatkan sebuah sistem keamanan suatu jenis acakan dengan memodifikasi algoritma yang digunakan yaitu dengan menggunakan fungsi algoritma RSA untuk memodifikasi acakan BISS agar keamanan data bisa menjadi lebih kuat dibandingkan sebelumnya.
Methods of posture analysis for computer workers
Authors: Maheronnaghsh Sara , Santos Joana , Vaz M. 
Published: October 2018

Musculoskeletal disorders (MSDs) have been identified as a predisposing factor for lesser productivity and are considered to be a major occupational health problem contributing significantly to absenteeism, disability and loss of productivity. Computer users may develop musculoskeletal disorders due to the forces applied, muscle use, posture and wrist velocity and acceleration exposures during computer use. Work-related musculoskeletal disorders (WMSDs) in computer users cause substantial worker discomfort, disability and loss of productivity. The aim of this study is to review systematically the relevant literature on applicable posture analysis methods to computer workers. A bibliographic survey based on PRISMA statement methodology was performed. A review on different approaches for computer workers posture was accomplished and noted that the simultaneous utilization of the different methods allows achieving better posture analysis, compared to situations when each one of them was used individually.
Preservasi Naskah Kuno Sasak Lombok Berbasis Digital dan Website
Authors: Anwar Muhammad Tajuddin , Husain Husain , Jaya Nenet Natasudian 
Published: October 2018

Salah satu warisan budaya nenek moyang bangsa Indonesia yang sangat bernilai adalah naskah kuno (manuskrip) yang ditulis dalam berbagai aksara dan bahasa. Dan satu diantaranya adalah Naskah Kuno Sasak, yang merupakan dokumen peninggalan nenek moyang Suku Sasak di Nusa Tenggara Barat, yang ditulis dengan tangan atau dalam bentuk asli sebelum dicetak. Digitalisasi adalah proses alih media dari bentuk tercetak, audio, maupun video, dilakukan untuk membuat arsip dokumen digital. Digitalisasi memerlukan peralatan seperti komputer, scanner, operator, media, sumber, dan software. Metode interpretatif dan perspektif, dipengaruhi oleh desain perspektif, seperti desain partisipatif dan desain sistem, melibatkan teori sistem yang layak. Digitalisasi Naskah Kuno Sasak merupakan perancangan interface menggunakan Framework Jquery Mobile dan penyimpanan data menggunakan basis data MySQL, sedangkan bahasa pemrograman menggunakan PHP. Digitalisasi sistem informasi ini menggunakan sistem operasi phonegap. Hasil dari perancangan ini adalah sebuah aplikasi Digitalisasi Naskah Kuno Sasak yang akan memudahkan dalam mendapatkan segala informasi mengenai Naskah Kuno Sasak. Hasil pengujian menunjukkan bahwa aplikasi ini dapat memberikan informasi sesuai dengan kebutuhan pengguna, seperti informasi Naskah Tulisan dalam bentuk; Lontar, tulisan Arab Melayu dan lain sebagainya. AbstractOne of the most valuable ancestral heritages of the Indonesian nation is the ancient manuscripts written in various letters and languages. And one of them is the Sasak Ancient Manuscripts, which is a relic of the ancestor of the Sasak tribe in West Nusa Tenggara, written by hand or in original form before printing. Digitalization is the process of media transfer from printed form, audio, or video, to create digital document archives. Digitalization requires equipment such as computers, scanner, operator, media, sources, and software. Interpretive and perspective methods are influenced by perspective design, such as participatory design and system design, inwhich involving proper systems theory. Digitalization of Ancient Sasak Manuscripts is an interface design using Jquery Mobile Framework and data storage using MySQL database, while programming language using PHP. Information System Digitalization uses an operating system made using phonegap. The result of this design is an application of Ancient Sasak Manuscripts Digitalization which is useful to facilitate especially the younger generation in getting information about Ancient Sasak Manuscripts.The results of testing obtained that the application can provide information in accordance with user needs, such as informations of writing Manuscripts in the form of Lontar, Malay Arabic and so forth.
POTENTIOMETRIC FLOW-INJECTION DETERMINATION OF MERCURY IONS USING DIANTIPYRILPROPYLMETHAN BASED ELECTRODE
Authors: Tataeva S. D. , Ramazanov A. Sh. , Magomedov K. E. , Zeynalov R. Z. 
Published: October 2018

The possibility of using diantipyrylpropylmethane (DAPPM) as an electrode-active membrane component of the mercury-selective electrode (Hg-SE) is shown. To clarify the mechanism of membrane functioning we studied the equilibrium in the “membrane-solution” system as a function of the medium acidity and amount of the ionophore. The potentiometric selectivity coefficients of Hg-SE are determined with respect to some anions and cations by the method of bionic potentials. DAPPM at pH 0 - 1.5 is in the cation form, and mercury ions in 0.1 M HCl — in the form of a trichloromercurium ion. The ion associate DAPPM + [HgCl3]-formed under these conditions is the most stable at pH 1 and pCl 1, and the membrane responds only to trichloromercurate ions.. A mercury-selective electrode with an optimized membrane composition (in wt. %) contains: PVC — 32.32; o-NPOE — 64.63; DAPPM — 3.05 (DAPPM concentration 100 mM). The electrochemical characteristics are determined: the linear range (1 x 10-4- 1 x 10-2M) and slope of the electrode function (50 mV/dec). The operating range (pH 0 - 1.5), detection limit (6.3 x 10-5M), and the response time (15 - 20 sec) are determined. For optimal operation of the flow-injection system, a selection of the carrier stream has been made, which affects the stability of the line, the sensitivity and the performance of the analysis. The proposed electrode is used as a detector in the flow-injection determination of mercury in sewage water and “Achromin” cream. Optimum operation conditions of the flow-injection system which ensure the stability of the baseline, as well as the maximum sensitivity and performance of the analysis, are found. The correctness of the results of the determination of mercury is confirmed in spike tests.
ПСИХОЛОГІЧНА ПРОБЛЕМАТИКА ЕЛІТ І МАС У ДОРОБКУ Д. ДОНЦОВА Й В. ЛИПИНСЬКОГО
Authors: Mojsijenko Yaroslav 
Published: October 2018

У статті проаналізовано основні праці ідеологів української національної думки першої половини ХХ ст. Д. Донцова й В. Липинського. Актуалізовано проблему виокремлення соціально-психологічних ідей у публіцистичній спадщині. У доробку вчених виділено концепції національної аристократії та боротьби активної меншості проти пасивної більшості (В. Липинський), самодостатнього націоналізму (Д. Донцов), дотичні до проблематики психологічної елітології. Виокремлено й проаналізовано ідею стихійного свідомого (В. Липинський). Розкрито авторське уявлення відносин між елітами та масами через явище персо­ніфікації. Показано, що політичне лідерство мислиться через поняття імперіалізму. Психологічними ознаками імперіалізму є стихійне прагнення політичного лідера до розширення влади, віра в законність, потрібність, правдивість своїх дій (В. Липинський). Виокремлено психологічні складники концепції націоналізму Д. Донцова, яка характеризуються агресивністю, ірраціональністю, знеціненням раціональних компонентів свідомості й поцінуванням емоційних та афективних складників, приматом надіндивідуальних і надгрупових інтересів перед індиві­дуальними інтересами особи. Показано, що конструкт волі є базовим для націєтворчих концепції авторів. Припущено, що спільним для обох дослідників визначальним психологічним конструктом у взаємодії між масами й елітами виступає неусвідомлюване прагнення національного самоздійснення. Висловлено думку про пов’язаність на проблемологічному рівні концепцій та ідей, розроблених українськими дослідниками, із відомими тогочасними соціально-психологічними концепціями в царині психології мас й еліт. Відзначено по­дібність елітологогічних концепцій В. Липинського з психоаналітичними поло­женнями З. Фройда стосовно взаємодії лідера та мас.
Law and Love: Legal Terminology in Roman Elegy
Authors: Cummings Caitlynn 
Published: October 2018

This paper analyses the use of legal terminology in Roman love elegy of the 1st century BCE. Catullus, Tibullus, and Ovid all employ this seemingly strange vocabulary in their love poetry for different ends, while also sharing some specific similarities. This legal vocabulary does not make these love poems stilted, dry, nor unemotional, but is used deftly and rather indicates an interesting layer of Roman concern and preoccupation.
Mempelajari Karakteristik Pengeringan Kerupuk Sayur
Authors: Subagya Annie Widya , Tamrin Tamrin , Sugianti Cicih , Suhandy Diding 
Published: October 2018

Kerupuk merupakan salah satu produk makanan kering yang populer dikalangan masyarakat Indonesia. Penambahan daun singkong kedalam adonan kerupuk untuk memanfaatkan ketersediaan daun singkong terutama saat panen. Penelitian ini bertujuan untuk mengetahui beberapa karakteristik pengeringan kerupuk sayur. Pengeringan kerupuk dilakukan dengan sinar matahari dan alat pengering tipe rak dengan suhu pengering 50°C ketebalan 2 mm, 3 mm, 4 mm. Hasil penelitian menunjukkan bahwa pengeringan menggunakan alat pengering dengan ketebalan 2 mm, 3 mm, dan 4 mm memiliki waktu pengeringan selama 3,5-4,5 jam yang lebih cepat dibandingkan dengan pengeringan sinar matahari dengan perlakuan yang sama membutuhkan waktu yaitu 4,5-5,5 jam. Penurunan kadar air pada alat pengering lebih cepat dibandingkan dengan pengeringan dengan sinar matahari. Kadar air akhir pada pengeringan alat memiliki nilai rata-rata 8,28% yang lebih rendah dibandingkan pengeringan sinar matahari yaitu 12,95%. Perubahan warna yang terjadi setelah proses pengeringan menggunakan alat pengering dan sinar matahari menghasilkan nilai <0,5 yang memiliki arti tidak jelas atau tidak mengalami perubahan setelah dilakukan proses pengeringan. Penyusutan diameter bahan pada alat pengering memiliki nilai 11,92% yang lebih besar dari pengeringan sinar matahari. Nilai rata-rata kadar air keseimbangan (Me) pada alat pengering yaitu 7,348 lebih rendah dibandingkan pada pengeringan sinar matahari. Nilai konstanta pengeringan pada alat pengering lebih memiliki nilai 12,05% lebih tinggi dibandingkan dengan pengeringan sinar matahari yaitu 8,28%.
Eksekusi Barang Rampasan Hasil Tindak Pidana Kehutanan Pasca Putusan Mahkamah Konstitusi Nomor 021/PUU-III/2005
Authors: Rifai Eddy , Triyono Rakhmat 
Published: October 2018

This study examines the execution of the judgment against the spoils of crime in forestry. Research using normative juridical approach and empirical jurisdiction. Execution of judgments against the state spoils of criminal offenses in the field of forestry, the injunction decision declared goods confiscated for the state not to do execution the form of an auction, because of legislation prohibiting the sale of forest products obtained from crime in protected forests. Perspective execution of court decisions to loot the proceeds of crime in the field of forestry is to judge using breakthrough progressive law, the court ruled that the injunction which reads "Evidence confiscated to the state and used for social purposes".
Rembug Pelayanan Publik (RPM) Sebagai Aktualisasi Pelayanan Publik Berlandaskan Demokrasi Pancasila
Authors: Nuriyanto Nuriyanto 
Published: October 2018

Dynamic development of society, they want the public bureaucracy to be able to provide the public services more professional, effective, simple, transparent, open, timely, responsive and adaptive. With excellent public service, to build a human quality in the sense of increasing the capacity of individuals and communities to determine actively its own future. Actualization of democratic precepts in the public services delivery in Indonesia starting point on the importance of community participation ranging from formulating criteria for the services, how the delivery of the services, arranging each engagement, public complaints mechanism set up by the monitoring and evaluation of the implementation of the public services in order to co-together build a commitment to create quality of the public services. It’s all been contained in the Law 25 of 2009 on Public Services, certainly it has been based on the precepts of the democracy of Pancasila. Rembug of the public services as an actualization of the public services based on the democracy of Pancasila.