bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrasonographic characterization of cervical lymph nodes in healthy dogs
Authors: Ruppel Marissa J. , Pollard Rachel E. , Willcox Jennifer L. 
Published: July 2019

AbstractUltrasonography provides
a minimally invasive method to evaluate the cervical lymph nodes in dogs as part of staging head and neck cancer; however, standardized cohesive reports of the normal lymph node size and appearance are lacking. The purpose of this prospective, descriptive, reference interval study was to characterize the ultrasonographic appearance of cervical lymph nodes in 27 clinically healthy dogs. The size, shape, echogenicity, and margination of the mandibular, medial retropharyngeal, and superficial cervical lymph nodes were evaluated and correlated with age, breed, sex, body weight, and stage of dental disease. The appearance of the lymph nodes was variable among the population. The majority were cigar or ovoid in shape with smooth margins. The echogenicity of the mandibular lymph nodes was predominantly hypoechoic whereas the medial retropharyngeal lymph nodes were predominantly isoechoic compared to the salivary glands. The superficial cervical lymph nodes were predominantly hyperechoic to the surrounding muscle bellies. Higher body weight and younger age were associated with increased size in the medial retropharyngeal and superficial cervical lymph nodes (P‐values < .05). Sex and breed were not found to correlate with lymph node characteristics, and there was no trend noted in lymph node appearance associated with dental disease. These data establish normal parameters for the ultrasonographic size and appearance of cervical lymph nodes in dogs and can provide a reference of comparison for future canine cervical ultrasounds, which can be considered for routine staging procedures for head and neck cancer.
Reclutamiento forzado de niños y niñas (abduction) en el conflicto armado colombiano: los menores de 18 años como víctimas con protección especial reforzada en el DIH y DIDH
Authors: Alarcón Palacio Yadira Elena 
Published: July 2019

Se trabaja el problema de los niños y niñas soldados, víctimas del reclutamiento forzado. Con revisión del tratamiento de los niños y niñas en la guerra en el Derecho Internacional Humanitario (DIH) y en el Derecho Internacional de los Derechos Humanos (DIDH) con énfasis en la edad de protección en los instrumentos internacionales. Se analiza el reclutamiento forzado en las normas internas como causa del Estado de cosas inconstitucional por desplazamiento forzado, para llegar al problema de los niños y niñas soldado de las FARC-EP y su tratamiento en la implementación del Acuerdo de Paz. Se concluye que en la discusión de la edad, la Corte Constitucional asume una solución ambigua al dar prevalencia a normas internacionales posteriores a garantías constitucionales que ya se tenían en el derecho interno. Colombia tiene una deuda pendiente con su infancia perdida.
The Effect of Pitching Frequency on the Hydrodynamics of Oscillating Foils
Authors: Hemmati Arman , Smits Alexander J. 
Published: July 2019

Abstract
The effects of two different pitching frequencies (that is, Strouhal number, St) on the wake structure generated by two foils of aspect ratio 1.0 are examined numerically at a Reynolds number of 10,000. Strouhal numbers of 0.5 and 0.2 were studied, the first corresponding approximately to the peak in efficiency and the second corresponding to the point where the thrust is equal to the drag (the free-swimming condition). The two foils have either a square trailing edge or a convex trailing edge that mimics the shape of the caudal fin exhibited by certain species of fish. In previous works, the convex trailing edge panel was found to have higher thrust and efficiency compared with the square panel trailing edge. Here, these differences are related to their characteristic vortex formation and detachment processes leading to differences in wake coherence and extension. The wake of the square panel at St = 0.2 transitions slowly from a reverse von Kármán street (2S) pattern to a paired (2P) system as the wake develops downstream, whereas at St = 0.5, the wake almost immediately takes on a 2P form with an attendant split in the wake structure. For the convex panel, the transition from a 2S to a 2P structure at St = 0.2 is slower than that seen for the square panel, and for St = 0.5, the wake undergoes an abrupt transition leading to two distinct vortex streets that evolve at a considerably slower rate than seen for the square panel.
Biomechanical In Vitro Test of a Novel Dynamic Spinal Stabilization System Incorporating Polycarbonate Urethane Material Under Physiological Conditions
Authors: Beckmann Agnes , Nicolini Luis Fernando , Grevenstein David , Backes Hermann , Oikonomidis Stavros , Sobottke Rolf , Kobbe Philipp , Hildebrand Frank , Stoffel Marcus , Markert Bernd , Siewe Jan , Herren Christian 
Published: July 2019

Abstract
Posterior dynamic stabilization systems (PDSS) were developed to provide stabilization to pathologic or hypermobile spinal segments while maintaining the healthy biomechanics of the spine. Numerous novel dynamic devices incorporate the temperature and moisture dependent material polycarbonate urethane (PCU) due to its mechanical properties and biocompatibility. In this study, standardized pure moment in vitro tests were carried out on human lumbar spines to evaluate the performance of a device containing PCU. An environmental chamber with controlled moisture and temperature was included in the setup to meet the requirements of testing under physiological conditions. Three test conditions were compared: (1) native spine, (2) dynamic instrumentation, and (3) dynamic instrumentation with decompression. The ranges of motion, centers of rotation, and relative pedicle screw motions were evaluated. The device displayed significant stiffening in flexion–extension, lateral bending, and axial rotation load directions. A reduction of the native range of motion diminished the stiffening effect along the spinal column and has the potential to reduce the risk of the onset of degeneration of an adjacent segment. In combination with decompression, the implant decreased the native range of motion for flexion–extension and skew bending, but not for lateral bending and axial rotation. Curve fittings using the sigmoid function were performed to parameterize all load-deflection curves in order to enhance accurate numerical model calibrations and comparisons. The device caused a shift of the center of rotation (COR) in the posterior and caudal direction during flexion–extension loading.
Development and Evaluation of a Subject-Specific Lower Limb Model With an Eleven-Degrees-of-Freedom Natural Knee Model Using Magnetic Resonance and Biplanar X-Ray Imaging During a Quasi-Static Lunge
Authors: Dejtiar David Leandro , Dzialo Christine Mary , Pedersen Peter Heide , Jensen Kenneth Krogh , Fleron Martin Kokholm , Andersen Michael Skipper 
Published: July 2019

Abstract
Musculoskeletal (MS) models can be used to study the muscle, ligament, and joint mechanics of natural knees. However, models that both capture subject-specific geometry and contain a detailed joint model do not currently exist. This study aims to first develop magnetic resonance image (MRI)-based subject-specific models with a detailed natural knee joint capable of simultaneously estimating in vivo ligament, muscle, tibiofemoral (TF), and patellofemoral (PF) joint contact forces and secondary joint kinematics. Then, to evaluate the models, the predicted secondary joint kinematics were compared to in vivo joint kinematics extracted from biplanar X-ray images (acquired using slot scanning technology) during a quasi-static lunge. To construct the models, bone, ligament, and cartilage structures were segmented from MRI scans of four subjects. The models were then used to simulate lunges based on motion capture and force place data. Accurate estimates of TF secondary joint kinematics and PF translations were found: translations were predicted with a mean difference (MD) and standard error (SE) of 2.13 ± 0.22 mm between all trials and measures, while rotations had a MD ± SE of 8.57 ± 0.63 deg. Ligament and contact forces were also reported. The presented modeling workflow and the resulting knee joint model have potential to aid in the understanding of subject-specific biomechanics and simulating the effects of surgical treatment and/or external devices on functional knee mechanics on an individual level.
Globally Approximate Gaussian Processes for Big Data With Application to Data-Driven Metamaterials Design
Authors: Bostanabad Ramin , Chan Yu-Chin , Wang Liwei , Zhu Ping , Chen Wei 
Published: July 2019

Abstract
We introduce a novel method for Gaussian process (GP) modeling of massive datasets called globally approximate Gaussian process (GAGP). Unlike most large-scale supervised learners such as neural networks and trees, GAGP is easy to fit and can interpret the model behavior, making it particularly useful in engineering design with big data. The key idea of GAGP is to build a collection of independent GPs that use the same hyperparameters but randomly distribute the entire training dataset among themselves. This is based on our observation that the GP hyperparameter approximations change negligibly as the size of the training data exceeds a certain level, which can be estimated systematically. For inference, the predictions from all GPs in the collection are pooled, allowing the entire training dataset to be efficiently exploited for prediction. Through analytical examples, we demonstrate that GAGP achieves very high predictive power matching (and in some cases exceeding) that of state-of-the-art supervised learning methods. We illustrate the application of GAGP in engineering design with a problem on data-driven metamaterials, using it to link reduced-dimension geometrical descriptors of unit cells and their properties. Searching for new unit cell designs with desired properties is then achieved by employing GAGP in inverse optimization.
Influence of Oxidation on Estimation of Long-Term Creep Rupture Strength of 2.25Cr–1Mo Steel by Larson–Miller Method
Authors: Abe Fujio 
Published: July 2019

AbstractThe influence of oxidation on the estimation of long-term creep rupture strength is investigated for 2.25% chromium (Cr)–1% molybdenum (Mo) steel specified as JIS STBA 24, JIS SCMV 4 NT, and ASTM A542/A542M by the Larson–Miller method using creep rupture data in the National Institute for Materials Science (NIMS) Creep Data Sheets at 450–650 °C for up to 313,000 h. The creep rupture data exhibit a change in slope of the stress versus time to rupture curves due to oxidation in air during 600 °C creep tests at 15,000–40,000 h and 650 °C tests at 2000–3500 h for different size specimens, which indicates degradation in creep life by the oxidation. The estimated 100,000 h creep rupture strength using regression analysis is increased by the elimination of long-term data degraded by the oxidation. Several metallurgical factors, such as the initial strength represented by the 0.2% proof stress at the creep test temperature and the concentration of aluminum (Al) impurity, also affect the creep life of the tested steel.
How did the tobacco ban increase inmates’ body weight during incarceration in Canadian federal penitentiaries? A cohort study
Authors: Johnson Claire , Chaput Jean-Philippe , Diasparra Maikol , Richard Catherine , Dubois Lise 
Published: July 2019

ObjectiveThis study aimed to determine how inmates’ body weight changed during incarceration in Canadian federal penitentiaries, based on their history of tobacco use. Since tobacco was banned from all Canadian federal penitentiaries in 2008, little is known about the unintended health consequences of this ban, especially on inmates’ body weight.DesignCohort study.SettingParticipants were male and female inmates incarcerated for at least 6 months in Canadian federal penitentiaries. We collected data from 10 institutions in two Canadian regions (Ontario and Atlantic).ParticipantsWe collected data from 754 inmates who volunteered to participate in the study.InterventionThis study examined weight change in relation to a history of tobacco use. In 2016–2017, anthropometric data were collected and compared with recorded anthropometric data at the beginning of incarceration (mean follow-up of 5.0±8.3 years). Self-reported data on tobacco and substance use were collected. Weight change was compared between inmates with and without a history of tobacco use.OutcomesThe main outcome measures were body weight change (kg), body mass index (BMI) change (kg/m2), annual weight change (kg/year), and BMI and waist circumference (cm) at the time of the interview.ResultsDuring incarceration, ex-smokers gained more than twice the amount of weight compared with non-smokers (7.5 kg weight gain for smokers vs 3.7 kg weight gain for non-smokers). Once adjusted for covariates in a regression analysis, for inmates who gained the most weight (75th and 90th percentiles), non-smokers had, respectively, 1.64 and 2.3 lower BMI points than ex-smokers.ConclusionsDuring incarceration in Canadian federal penitentiaries, inmates with a history of tobacco use gained significantly more weight than non-smokers. This put them at increased risk of developing obesity-related health problems. This information is important for the prison setting when planning related programmes and regulation.
Sex disparities in premature adult mortality in Estonia 1995–2016: a national register-based study
Authors: Rahu Kaja , Rahu Mati , Zeeb Hajo 
Published: July 2019

ObjectivesTo quantify sex disparities in cause-specific premature adult mortality in Estonia, to determine the causes of death with the largest differences, to provide insight into related behaviours and to offer some guidance to public health policy-makers based on the results of the study.DesignA national register-based study.SettingEstonia.DataIndividual records of deaths at ages 20–69 years in 1995–2016 from the Estonian causes of death register; data on tobacco smoking and alcohol consumption in the adult population in 1996–2016 from the biennial postal survey of health behaviour.Main outcome measuresOverall and cause-specific age-standardised mortality rates, average annual percentage changes in mortality, and cause-specific men-to-women mortality rate ratios were calculated. In addition, the age-standardised prevalence proportions of tobacco smoking and alcohol consumption and men-to-women prevalence rate ratios were determined.ResultsOverall premature adult mortality decreased considerably during 1995–2016, but no reduction was observed with respect to the large relative sex disparities. In circulatory disease mortality, the disparities widened significantly over time. Extremely high mortality rate ratios were observed for cancer of the upper aerodigestive tract and for lung cancer. There was a stable, more than fivefold male excess mortality from external causes. A fourfold male disadvantage was evident for alcohol poisoning, mental disorders due to alcohol and alcohol-related degeneration of the nervous system as a group. The prevalence of tobacco smoking and harmful alcohol consumption among men exceeded that among women by factors of two and six, respectively.ConclusionsEven though premature adult mortality has markedly decreased over time, there has been no success in diminishing the large sex differences in the mortality patterns, mostly associated with smoking and excessive alcohol consumption, both more prevalent among men. Estonia needs a comprehensive and consistent alcohol policy while maintaining and further developing antitobacco measures.
Telehealth and texting intervention to improve HIV care engagement, mental health and substance use outcomes in youth living with HIV: a pilot feasibility and acceptability study protocol
Authors: Wootton Angie R , Legnitto Dominique A , Gruber Valerie A , Dawson-Rose Carol , Neilands Torsten B , Johnson Mallory O , Saberi Parya 
Published: July 2019

IntroductionYouth and young adults living with HIV (YLWH) experience worse clinical outcomes than adults and high rates of behavioural health challenges that impact their engagement in care and adherence to antiretroviral therapy. This study in the San Francisco Bay area aims to evaluate the feasibility, acceptability and preliminary clinical outcomes of a 12-session telehealth counselling series provided to 80 YLWH, including education, motivational enhancement and problem-solving around HIV care, mental health, substance use and other challenges. Findings will provide information about benefits and challenges of telehealth counselling for YLWH and will guide the development of new technology-based strategies for care.Methods and analysisThe Youth to Telehealth and Text to Improve Engagement in Care study is a pilot randomised, crossover trial examining the feasibility and acceptability of a telehealth counselling intervention consisting of twelve 20–30 min weekly sessions focused on identifying and problem-solving around barriers to HIV care access and adherence and on addressing mental health, substance use and/or other issues. Participants also receive text messages for check-ins, appointment reminders and to improve engagement. Participants complete quantitative online surveys at baseline, 4 and 8 months and qualitative exit interviews. Clinical outcomes, including plasma HIV RNA and CD4+ cell count, are collected from medical records. Study staff will explore outcomes of the intervention using quantitative and qualitative methods.Ethics and disseminationThis study and its protocols have been approved by the University of California, San Francisco (UCSF) Institutional Review Board. Study staff will work with the UCSF Center for AIDS Prevention Studies’ Community Engagement Core and the Youth Advisory Panel to disseminate results to the community, participants and the academic community.Trial registrationNCT03681145.
Association between alcohol consumption and impaired work performance (presenteeism): a systematic review
Authors: Thørrisen Mikkel Magnus , Bonsaksen Tore , Hashemi Neda , Kjeken Ingvild , van Mechelen Willem , Aas Randi Wågø 
Published: July 2019

ObjectivesThe aim of this review was to explore the notion of alcohol-related presenteeism; that is, whether evidence in the research literature supports an association between employee alcohol consumption and impaired work performance.DesignSystematic review of observational studies.Data sourcesMEDLINE, Web of Science, PsycINFO, CINAHL, AMED, Embase and Swemed+ were searched through October 2018. Reference lists in included studies were hand searched for potential relevant studies.Eligibility criteriaWe included observational studies, published 1990 or later as full-text empirical articles in peer-reviewed journals in English or a Scandinavian language, containing one or more statistical tests regarding a relationship between a measure of alcohol consumption and a measure of work performance.Data extraction and synthesisTwo independent reviewers extracted data. Tested associations between alcohol consumption and work performance within the included studies were quality assessed and analysed with frequency tables, cross-tabulations and χ2tests of independence.ResultsTwenty-six studies were included, containing 132 tested associations. The vast majority of associations (77%) indicated that higher levels of alcohol consumption were associated with higher levels of impaired work performance, and these positive associations were considerably more likely than negative associations to be statistically significant (OR=14.00,phi=0.37, p<0.001). Alcohol exposure measured by hangover episodes and composite instruments were over-represented among significant positive associations of moderate and high quality (15 of 17 associations). Overall, 61% of the associations were characterised by low quality.ConclusionsEvidence does provide some support for the notion of alcohol-related presenteeism. However, due to low research quality and lack of longitudinal designs, evidence should be characterised as somewhat inconclusive. More robust and less heterogeneous research is warranted. This review, however, does provide support for targeting alcohol consumption within the frame of workplace interventions aimed at improving employee health and productivity.PROSPERO registration numberCRD42017059620.
Impact of clinical posting in psychiatry on the attitudes towards psychiatry and mental illness in undergraduate medical students
Authors: Desai Rishi , Panchal Bharat , Vala Ashok , Ratnani Imran Jahangirali , Vadher Sneha , Khania Pushpa 
Published: July 2019

BackgroundA major public health problem around the world today is mental illness. Although there are several studies on the topic, it is rarely conducted in the context like the current study.AimsThis study aims to find out the attitudes of medical students towards psychiatry and mental illness as a clinical medicine major and evaluate the effects of clinical posting on their attitudes towards psychiatry and mental illness.MethodsThis is a longitudinal study of 6 months’ duration conducted with students in their fifth semester of medical college in Western India during the academic year of 2016–2017. The participants were assessed by pro forma containing demographic details, and the questionnaires—Attitude Towards Psychiatry-30 items (ATP-30) scale and Mental Illness Clinician’s Attitude (MICA) scale, which were presented to the students at the beginning and at the end of their psychiatry clinical posting. The statistical analysis was done with GraphPad, InStat V.3.06. A p value <0.05 was considered statistically significant.ResultsThe students’ attitudes towards psychiatry were neutral at the beginning of the psychiatry clinical posting, and improved significantly at the end of the posting on both scales: ATP-30 (p=0.002) and MICA (p=0.048). The students became more positive towards the subject and mental illness in general, negative attitudes also reduced but the change was not statistically significant (p=0.058). We found significant improvement in students’ thinking towards being a psychiatrist in the future post-term (p=0.0002). The changes in attitude in terms of gender were equivocal, with an increase in positive attitude and reduction in negative attitude post-term in both sexes.ConclusionPsychiatry clinical posting aids in cultivating positive attitude towards psychiatry and mental illness and reduces the stigma associated with the students of this major and psychiatric patients.