bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advantages of social foraging in crab spiders: Groups capture more and larger prey despite the absence of a web
Authors: Dumke Marlis , Herberstein Marie E. , Schneider Jutta M. 
Published: July 2018

AbstractAmong group‐living spiders, subsocial representatives in the family of crab spiders (Thomisidae) are a special case, as they build protective communal leaf nests instead of extensive communal capture webs. It could thus be inferred that antipredator benefits (e.g., enhanced protection in larger nests) rather than foraging‐related advantages (e.g., capture of more and larger prey) promote sociality in this family. Nonetheless, subsocial crab spiders do share prey, and if this behaviour does not reflect mere food scramble but has a cooperative character, crab spiders may offer insights into the evolution of social foraging applicable to many other cooperative predators that hunt without traps. Here, we performed a comparative laboratory feeding experiment on three of the four subsocial crab spider species—Australomisidia ergandros,Australomisidia socialisandXysticus bimaculatus—to determine if crab spiders derive advantages from foraging in groups. In particular, we tested artificially composed groups of five sibling spiderlings vs. single siblings in terms of prey capture success and prey size preference. Across species, groups had higher prey capture success (measured in terms of capture rates and capture latency) and were more likely to attack large, sharable prey—dynamics leading to reduced food competition among group members in favour of living and foraging in groups. Within groups, we further compared prey extraction efficiency among the three applied social foraging tactics: producing, scrounging and feeding alone. InA. ergandros, individuals were exceptionally efficient when using the non‐cooperative scrounger tactic, which entails feeding on the prey provided by others. Thus, our multispecies comparison confirms foraging advantages in maintaining a cooperative lifestyle for crab spiders, but also demonstrates the relevance of research into exploitation of cooperative foraging in this family.
Perspectives of cancer treatment providers regarding voluntary assisted dying in Victoria
Authors: Yoong Jaclyn , Franco Michael , William Leeroy , Poon Peter 
Published: July 2018

AbstractA survey of cancer treatment providers at our institution exploring their perspectives regarding voluntary assisted dying in Victoria and the imminent legislation showed that while almost all were aware of the Bill (92%), reported knowledge and understanding of it was much less (38%). As many clinicians supported the Bill as opposed it (28%); 44% were uncertain of their stance. Most were unwilling to directly provide voluntary assisted dying; if they did, would refer to palliative care services for ongoing support.
Making sense of newer treatment options for type 2 diabetes
Authors: Lee Phong Ching , Hare Matthew J. L. , Bach Leon A. 
Published: July 2018

AbstractOver the past decade, several new medications have been developed to treat type 2 diabetes mellitus. Large‐scale outcome trials have been performed with patients at high cardiovascular risk to assess the cardiovascular safety of these agents. These trials are changing the landscape of diabetes therapy with evidence beyond safety to cardiovascular benefits of sodium‐glucose cotransporter 2 (SGLT‐2) inhibitors and some glucagon‐like peptide‐1 receptor agonists. This review provides an overview of incretin‐based therapies and SGLT‐2 inhibitors with a particular focus on the results of published cardiovascular outcome trials, which have also provided unique opportunities to evaluate uncommon but potentially serious adverse events of these newer agents. The cardiovascular benefits of SGLT‐2 inhibitors and some glucagon‐like peptide‐1 receptor agonists suggest that they may be the preferred choice, usually as an add‐on to metformin, for patients with type 2 diabetes mellitus at high cardiovascular risk.
Medical Oncology Group of Australia position statement and membership survey on voluntary assisted dying
Authors: Karapetis Christos S. , Stein Brian , Koczwara Bogda , Harrup Rosemary , Milleshkin Linda , Parente Phil , Millward Michael , Haines Ian , Blinman Prunella , Olver Ian 
Published: July 2018

AbstractThe controversial topic of voluntary assisted dying (VAD) is receiving significant attention at state government levels and in the community. Acknowledging potential legalisation of VAD, the Medical Oncology Group of Australia (MOGA) undertook a survey of members to inform the development of a position statement on the subject. All MOGA members were invited to complete an anonymous online survey. The survey comprised 12 closed‐response categorical questions. Descriptive statistics were used to summarise the survey data. Majority views expressed in the survey would form the basis of a MOGA position statement on VAD. A total of 362 members completed the questionnaire, representing 55% of the membership; 47% of respondents disagreed with VAD; 36% agreed with VAD and the remaining members (17%) were ‘neutral’. A clear majority position was not established. Only 14% agreed that physicians involved in VAD should be required personally to administer the lethal medication; 94% supported conscientious objection of physicians to the VAD process; 95% agreed that a palliative care physician consultation should be required and 86% agreed with the need for the involvement of specialist psychiatry medical services before a patient can be deemed as suitable for VAD. The MOGA membership expressed a range of views on the topic of VAD. A clear majority‐held view to support a MOGA position that either supports or opposes VAD was not established. The position statement that flows from the survey encourages informed debate on this topic and brings into focus important considerations.
Biosimilars are coming: ready or not
Authors: Zalcberg John 
Published: July 2018

AbstractBiosimilars have had a sizeable impact on the availability and use of biologic medicines in Australia, particularly those prescribed for supportive care in oncology or to treat inflammatory diseases. Biosimilars of oncology drugs that modify disease processes are likely to be the next ‘wave’ of biosimilars to receive regulatory approval, both internationally and in Australia. Given their more tailored development pathway relative to reference biologics, biosimilar versions of these drugs have the potential to reduce substantially the burden on the healthcare system and increase patient access to treatment. However, there is some uncertainty regarding the regulatory approval pathway and expected clinical characteristics of biosimilars among Australian physicians. This review outlines the concept of biosimilarity and details the regulatory pathway leading to the approval of biosimilars. It also highlights the potential benefits to patients and the healthcare system, as well as opportunities stemming from the use of biosimilars in Australia. The Australian regulatory framework and rationale underlying the extrapolation of indications for a biosimilar to others held by the originator biologic, in the absence of a comparative clinical study, is also described. In addition to the benefits biosimilars may bring, Australia’s established cooperative clinical trial group programmes afford an opportunity for further innovation by providing a mechanism to expand the use of certain biosimilars to new disease indications.
The Nuclear RNA‐binding Protein RBSR1 Interactome in Trypanosoma cruzi
Authors: Wippel Helisa H. , Malgarin Juliane S. , Martins Sharon de Toledo , Vidal Newton M. , Marcon Bruna H. , Miot Hálisson T. , Marchini Fabricio K. , Goldenberg Samuel , Alves Lysangela R. 
Published: July 2018

AbstractTrypanosoma cruzi, the etiological agent of Chagas disease, has been widely studied, reflecting both its medical importance and the particular features that make this pathogen an attractive model for basic biological studies. The repression of transcripts by messenger ribonucleoprotein (mRNP) complexes is an important pathway of post‐transcriptional regulation in eukaryotes, including T. cruzi. RBSR1 is a serine‐arginine (SR)‐rich RNA‐binding protein (RBP) in T. cruzi that contains one RNA‐recognition motif (RRM); this protein has a primarily nuclear localization and is developmentally regulated, not being detected in metacyclic trypomastigotes. RBSR1 interacts with other RBPs, such as UBP1 and UBP2, and the nuclear SR‐protein TRRM1. Phylogenetic analysis indicated that RBSR1 is orthologous to the human splicing factor SRSF7, what might indicate its possible involvement in pre‐RNA processing. Accordingly, ribonomics data showed the enrichment of snoRNAs and snRNAs in the RBSR1 immunoprecipiatation complex, hence reinforcing the supposition that this protein might be involved in RNA processing in the nucleus.
An Open for Replication Study: The Role of Feedback Timing in Synchronous Computer‐Mediated Communication
Authors: Arroyo Diana C. , Yilmaz Yucel 
Published: July 2018

This study investigated the role of corrective feedback timing in the acquisition of Spanish noun–adjective gender agreement. Forty‐five learners completed a communicative task via synchronous computer‐mediated communication (SCMC) in one of three groups (immediate, delayed, control). The immediate‐feedback group received error reformulations immediately after their errors. The delayed‐feedback group did not receive feedback; however, at the end of the task, they were provided with an electronic document showing the errors they had made during the task with error reformulations. The control group performed the task without receiving feedback. The immediate‐feedback group outperformed the delayed‐feedback group in an oral production test, but there were no differences between the two feedback groups in a grammaticality judgment test. All study materials and data are made publicly available to encourage future replications.Open PracticesThis article has been awarded Open Materials and Open Data badges. All materials and data are publicly accessible via the Open Science Framework at https://osf.io/57zkv, the IRIS Repository at https://www.iris-database.org, and Supporting Information accompanying this article. Learn more about the Open Practices badges from the Center for Open Science: https://osf.io/tvyxz/wiki.
Adenosine diphosphate regulates MMP2 and MMP9 activity in malignant mesothelioma cells
Authors: Muscella Antonella , Cossa Luca Giulio , Vetrugno Carla , Antonaci Giovanna , Marsigliante Santo 
Published: July 2018

AbstractAlthough an association between cancer progression and matrix metalloproteinase (MMP) 2 and MPP9 expression has been known, the expression, nuclear localization, and physiologically controlled activation of these two MMPs have not been investigated in malignant mesothelioma cells. We examined the expression and intracellular localization of MMP2/9 in ZL55 malignant mesothelioma cells, as well as their regulation by ADP. Using real‐time PCR, we showed that activation of the P2Y1 receptor by ADP increased the expression of MMP2/9 mRNAs; MMP2/9 collected from conditioned media also showed an increase in activity; and ADP induced the nuclear localization of MMP2/9. The effects of ADP on transcription of the MMPs were due to activation of c‐Src, Akt, and NF‐κB, while ERK1/2 phosphorylation was needed for the increase in enzymatic activity and the regulation of nuclear import. We also showed that the nuclear localization of MMP2/9 induced by ADP causes the cleavage and inactivation of poly‐ADP‐ribose polymerase‐1. These findings may help to elucidate the mechanisms regulating MMP2/9 activation in ZL55 human epithelioid mesothelioma cells, and perhaps other cells. Therapeutic approaches that promote ADP accumulation in a tumor environment may constitute an effective means to induce anticancer activity.
Body dysmorphic disorder in pediatric dermatology
Authors: Dennin Margaret H. , Lee Margaret S. 
Published: July 2018

AbstractBody dysmorphic disorder is an obsessive‐compulsive spectrum disorder involving a perceived defect in physical appearance that most commonly develops in early adolescence and causes significant functional impairment and suicidality at much higher rates than in affected adults. Patients may also present with subthreshold body dysmorphic disorder or obsessive concerns over a diagnosable dermatologic condition, both of which can present similarly to body dysmorphic disorder. Pediatric dermatologists can play an important role in detecting body dysmorphic disorder and body dysmorphic disorder‐like symptoms, which may occur in as many as 20% of dermatology patients. Greater awareness of the prevalence, clinical presentation, and effect of these symptoms, as well as better screening tools and greater collaboration with our mental health colleagues, may lead to earlier, more effective intervention.
The Solvatofluorochromism of 2,4,6‐Triarylpyrimidine Derivatives
Authors: Rodríguez‐Aguilar José , Vidal Matías , Pastenes Camila , Aliaga Carolina , Rezende Marcos Caroli , Domínguez Moisés 
Published: July 2018

AbstractSeven new 2,4,6‐triarylpyrimidines were synthesized and their solvatofluorochromism investigated in 12 solvents and in an aqueous micellar solution of reduced Triton X‐100. A multiparametric analysis of their emission band showed that the solvent dipolarity and basicity were mainly responsible for their solvatofluorochromism, which arose from an internal charge‐transfer from a donor fragment to the pyrimidine acceptor, confirmed by theoretical calculations. In the micellar system, quenching of their fluorescence by addition of derivatives of 2,2,6,6‐tetramethylpiperidinoxyl (TEMPO) radical was investigated and the results were consistent with the spectral changes brought about by the micro‐heterogeneous system.
Hydrodynamic effects on oyster aquaculture systems: a review
Authors: Campbell Matthew D. , Hall Steven G. 
Published: July 2018

AbstractHydrodynamics (i.e. interactions of fluid motion with solid bodies) affect oyster aquaculture within every phase of farming. Although it has many direct and indirect implications to the success of any particular aquaculture endeavour, hydrodynamics is the least understood of environmental factors affecting oyster growth. As the industry continues to mature, it is imperative that the influence of hydrodynamics on oyster aquaculture is thoroughly understood. Hydrodynamics also interacts with other environmental factors, such as salinity, temperature, turbidity, food supply and oxygen, which affect the health and growth of oysters through mixing and transport. Proper siting and management of aquaculture requires a comprehensive understanding of the hydrodynamics involved and its impact on the culture of oysters. Unfortunately, literature is inconsistent on oyster feeding and growth response to the influence of hydrodynamics. Feeding and growth limiting velocities are reported that range from 1 to above 22 cm s−1. This is in contrast with thriving oyster reefs in a natural setting that exist and thrive above 15 cm s−1. Upweller systems have reported bulk velocities that range from 0.5 to 7.1 cm s−1. In practice, higher current velocities are desirable because they increase delivery of food to the oysters, improve water quality, and enhance dispersal of biodeposits. This paper summarizes the findings of those studies in regard to hydrodynamics and provides suggestions for future work.
Intracellular calcium chelating agent (BAPTA‐AM) aids stallion semen cooling and freezing–thawing
Authors: Wu Shuaishuai , Canisso Igor F. , Yang Weigang , Ul Haq Ihteshamu , Liu Qiang , Han Ying , Zeng Shenming 
Published: July 2018

AbstractThis study aimed to investigate the effects of different concentrations of 1,2‐bis‐(o‐aminophenoxy)‐ethane‐N,N,N0 N0‐tetraacetic acid, tetra‐acetoxymethyl ester (BAPTA‐AM), an intracellular calcium chelating agent, on stallion semen cooling and freezing–thawing. After collection, semen was extended (1:1 v/v) on a skim milk‐based extender, centrifuged and resuspended at 400 million/ml into cooling or freezing extenders containing 0, 5, 25, 50, 100 and 200 μΜ BAPTA‐AM. Motility parameters were assessed after cooling in Equitainer at 5°C for 12, 24, 48, 72 and 120 hr and after freezing–thawing. In addition, mitochondrial membrane potential, intracellular ATP, reactive oxygen species and malondialdehyde concentrations were measured in cryopreserved‐thawed semen. Cooled stored (48 hr) semen containing 50 μΜ BAPTA‐AM and control extender (0 μΜ BAPTA‐AM) was used to assess fertility. Inclusion of 50 μΜ BAPTA‐AM resulted in superior sperm motility parameters during cooled storage when compared to other groups (p < 0.05). Furthermore, semen cryopreserved in extender containing 50 μΜ BAPTA‐AM showed increased intracellular ATP and mitochondrial membrane potential, whereas reactive oxygen species and malondialdehyde were increased after thawing for all groups (p < 0.05). Addition of 50 μΜ BAPTA‐AM to cooling extender resulted in similar pregnancy rates to the control group (75% vs. 73.6%, respectively;p > 0.05). In conclusion, the addition of BAPTA‐AM to semen extenders aided stallion semen cryopreservation in a dose‐dependent manner. Furthermore, the cooling extender supplemented with 50 μΜ BAPTA‐AM could be used to prolong the sperm motility during cooling without apparently compromising fertility. Field trials should be conducted to assess fertility of cryopreserved stallion semen with BAPTA‐AM.
Regulating lobbying activities in the European Union: A voluntary club perspective
Authors: Năstase Andreea , Muurmans Claire 
Published: July 2018

AbstractThis article offers a systematic exploration of why interest groups sign up to the European Union Transparency Register, a non‐binding lobby regulation system. We distinguish between instrumental and normative perspectives to explain voluntary compliance, and find that concern for one's reputation represents the most important motivational driver. Based on this, we suggest that the Transparency Register can be understood as a “voluntary club” sponsored by European institutions. This theoretical perspective captures the appeal of the instrument among lobbyists, but also a number of inconsistencies in its current design, which make it unviable in the long term. We outline implications for the ongoing reform of the Transparency Register, and more generally for the regulation of lobbying activities. The analysis draws on semi‐structured interviews with various types of lobbyists active in Brussels, and on data from public consultations organized by the European Commission.
Three‐dimensional scanning for measurement of bulk density in gravelly soils
Authors: Scanlan C. A. , Rahmani H. , Bowles R. , Bennamoun M. 
Published: July 2018

AbstractThe measurement of bulk density in gravelly soils (>15% soil particles >2 mm) is more time‐consuming than for other soils. The excavation method, usually employed for measurement of bulk density in gravelly soils, includes excavating a void and calculating volume of the void from the weight and density of the material (e.g. sand and plaster cast) used to fill the void. A 3‐dimensional (3D) scanning system was developed to measure the volume of the void created when using the excavation method. The 3D scanning system combined a time‐of‐flight camera (Kinect ™), the KinectFusion algorithm, MeshLab and a portable computer to produce a 3D model of the void or plaster cast. Experiments were completed at three field sites where soil gravel (>2 mm) content ranged from 35 to 71% to assess the performance of the system. The void volume measured using the 3D scanning system was highly correlated with measurements using the plaster cast method (r = 0.99). The cumulative time taken to measure soil bulk density using 3D scanning was significantly (P < 0.001) less than for the sand replacement at 0–10, 10–20, 20–30 and 30–40 cm depth. The faster measurement of subsurface bulk density is a significant advantage of the 3D scanning system; the time taken to measure bulk density to 40 cm in 10 cm increments using the 3D scanning system was about one‐third of the sand method.
Like it or not? How the economic and institutional environment shapes individual attitudes towards multinational enterprises
Authors: Harms Philipp , Schwab Jakob 
Published: July 2018

AbstractThis paper analyses the determinants of people's attitudes towards foreign direct investment (FDI) using a survey‐based data set that covers a wide range of rich and poor countries. We find that both individual socioeconomic characteristics and macroeconomic and institutional factors shape agents’ attitudes towards multinational firms. Moreover, we find that the influence of an individual's characteristics—such as education and the status as an entrepreneur—on her/his perspective on multinationals depends on the respective country's per‐capita income. Our results confirm the conjecture that relative individual attitudes towards multinationals reflect distributional interests as suggested by economic theory.
US immigration policies and dynamics of cross‐border workforce in agriculture
Authors: Devadoss Stephen , Luckstead Jeff 
Published: July 2018

AbstractGiven the contentious debate on immigration, this study develops a dynamic model to analyse the effects of stricter border and domestic enforcement and streamlining the guest‐worker programme on cross‐border migration from Mexico, employment and production in US labour‐intensive and Mexican agriculture and the US and Mexican wage rates. The model incorporates labour‐leisure decisions of Mexican workers and labour market dynamics and linkages. The findings show stricter border and domestic controls exacerbate the labour‐shortage problems and reduce the US agricultural production. Streamlining the guest‐worker programme provides a steady supply of farm workers and has negligible impact on the US wage.
Reviewer Acknowledgements
Authors: Smith Robert 
Published: July 2018

Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 6, Number 4a Carmen Pérez-Sabater, Universitat Poltècnica de València, SpainErica D. Shifflet-Chila, Michigan State University, USAGunkut Mesci, Giresun University, TurkeyJohn Bosco Azigwe, Bolgatanga Polytechnic, GhanaJohn Cowan, Edinburgh Napier University, UKLaura Bruno, The College of New Jersey, USALisa Marie Portugal, Grand Canyon University, USALorna T. Enerva, Polytechnic University of the Philippines, PhilippinesMehmet Inan, Marmara University, TurkeyNicole Celestine, The University of Western Australia, Australia Robert SmithEditorial AssistantOn behalf of,The Editorial Board of Journal of Education and Training StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://jets.redfame.com