bluuebunny/crossref_metadata_2025_split huggingface dataset:
Features of ankylosing spondylitis at different stages in men and women
Authors: Cherentsova I. A. , Otteva E. N. 
Published: May 2019

The incidence of ankylosing spondylitis (AS) has recently increased with a substantial rise in the proportion of female patients, making this investigation relevant.Objective: to investigate the clinical and laboratory parameters of inflammatory activity and functional status in male and female patients with AS at different stages of the disease.Patients and methods. Examinations were performed in 119 patients (82 men and 37 women) (mean age, 36.4±0.9 years) with AS and 34 patients (24 men and 10 women) (mean age 27.0±1.6 years) with non-radiographic axial spondyloarthritis (nr-axSpA). The investigators used the 1984 modified New York criteria to confirm AS diagnosis and the 2009 ASAS classification criteria for axial spondyloarthritis. They also determined AS activity by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and functional status by the Bath Ankylosing Spondylitis Functional Index (BASFI) and the Bath Ankylosing Spondylitis Metrology Index (BASMI). For the calculation of enthesites, the validated index Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) was used; pain intensity in the last week was estimated using a visual analogue scale (VAS). Laboratory examination included the determination of ESR and HLA-B27 antigen. All the patients underwent a plain film of the pelvic bones; and patients with nr-axSpA had magnetic resonance imaging for sacroiliitis.Results and discussion. In both groups, there was a male preponderance and axial lesions were more common (among the patients with AS, there were 68.9% of the men with sacroiliac joint lesions and 53.7% of those with spinal involvement; among the patients with nr-axSpA, there were 80.0 and 67.6 %, respectively; p>0.05). The HLA-B27 antigen was detected in the majority of patients with AS (86.6% of men and 91.7% of women) and in those with nr-axSpA (91.6 and 80.0%, respectively). Uveitis was more common in women with AS (32.4%), less common in men with AS (17.1%); (p<0.05) and nr-axSpA (8.3%); uveitis was not observed in women with nr-axSpA (p<0.001). The pain according to VAS was more intense in women (48.1±3.4 mm; p<0.01); in the nr-axSpA group, its values were comparable in men and women (p>0.05). The BASDAI and BASFI scores were similar in women at all stages of the disease (p>0.05). The men with nr-axSpA had the best functional status (p<0.01) with the same BASDAI activity (p>0.05) compared with those with AS. The BASMI in patients with AS regardless of gender was higher than in those with nr-axSpA (p<0.01). High BASDAI activity was more frequently detected in women with AS and nr-axSpA than in men (64.9 and 60.0%, respectively; p<0.01). Low activity was not observed in any woman with nr-axSpA. Enthesitis was more common in women in both AS and nr-axSpA (81.0 and 80.0%, respectively; p<0.05).Conclusion. In women, AS and nr-ax-SpA are more severe, starting at their early stage, which is manifested by a higher activity, functional failure, and a higher frequency of extra-axial manifestations.
Tofacitinib is a modern solution to the problem of resistant rheumatoid arthritis
Authors: Menshikova I. V. , Strogonova V. V. 
Published: May 2019

Objective: to analyze the efficacy of tofacitinib (TOFA) in patients with an advanced stage of rheumatoid arthritis (RA) and previous methotrexate (MTX) failure according to comprehensive clinical and laboratory examination.Patients and methods. Nineteen patients (11 women and 8 men aged 29 to 71 years (mean age 53.47±10.53 years)) with a reliable diagnosis of RA according to the 2012 American College of Rheumatology (ACR) criteria were followed up. Due to a high disease activity (DAS28 averaged 5.84±0.89), the patients were prescribed TOFA 10 mg/day taken for 12 months. The disease activity indicators were assessed at baseline, 3, 6, and 12 months after the start of the study.Results and discussion. The effect of TOFA developed quite quickly: at 3 months of therapy, there were positive clinical, laboratory, and instrumental changes in most patients; 5 (26.3%) patients achieved the goal of treatment. At 12 months of therapy, 8 patients achieved DAS28 remission and 3 patients had a low disease activity; moderate RA activity persisted in 7 patients; and a high disease activity was seen in 1 patient; these SDAI activity indicators were observed in 2, 8, 7, and 2 patients, respectively. According to the ACR criteria, 20, 50, and 70% improvements were achieved by 8, 6, and 3 patients, respectively. No serious adverse reactions were recorded. The findings confirm the good efficacy and safety of TOFA in the treatment of patients with an advanced stage of RA.Conclusion. The innovative mechanism of TOFA allows a significant number of patients, in whom MTX therapy was not effective enough, to achieve the goal of treatment.
Behсet's disease: clinical and gender associations
Authors: Alekberova Z. S. , Lisitsyna T. A. , Goloeva R. G. , Davydova G. A. 
Published: May 2019

Objective: to compare the frequency of clinical manifestations of Behcet's disease (BD) in patients of both sexes in a Russian cohort.Patients and methods. Examinations were made in 425 patients (285 men and 140 women; mean age, 33.2±10.2 years; median duration of BD, 134.3 [60.0; 192.0] months (about 11 years) with a reliable diagnosis of the disease. 208 (48.9%) patients were ethnic residents of the North Caucasus. The activity of BD was assessed using the BD Current Activity Form; the disease severity was evaluated according to the classification proposed by Ch. Zouboulis.Results and discussion. In men with BD in the Russian cohort, the activity and severity of the disease were significantly higher and the HLA-B5(51)- antigen was more common. There was an association of male sex with thromboses in the deep cerebral veins and cerebral sinuses, damage to the eyes and skin (pseudopustulosis and pseudofolliculitis), genital ulcers, and a positive pathergy test. The findings are consistent with the results of studies of other patient cohorts: Iranian, German, Turkish ones, in which the men were more frequently detected to have damage to the vessels, skin and eyes.Conclusion. In the Russian patient cohort, the male sex is associated with high BD activity, severe organ damages, and HLA-B5(51)-antigen positivity, which is the basis for prescribing immunosuppressive therapy in men with early-stage BD.
An Empirical Study on the Relationship Between Chinese Teachers’ Attitudes Toward Identity and Teacher Autonomy
Authors: Qian Lina , Huang Haiquan 
Published: May 2019

Abstract
Teacher identity formation provides a direction for the development of autonomy (Huang & Benson, 2013). However, the process of identity formation is complex and how this process influences teacher autonomy has not been sufficiently studied. To contribute to knowledge in this field, the present study investigated the relationship between teachers’ attitudes toward teacher identity and teacher autonomy. We first observed 14 Chinese College English teachers’ classroom teaching. Following that, we conducted stimulated recall interviews with all the teachers to pinpoint their autonomous practices. Finally, we conducted semi-structured interviews to investigate these teachers’ attitudes toward their identities. One of the main findings was that the teachers who held a positive attitude toward their professional identity were more autonomous in their teaching practices than those with a negative attitude. The findings invite us to conclude that teachers’ attitudes toward their professional identity are positively associated with teacher autonomy.
Factors Related to EFL/ESL Learners’ Reading Strategy Use: A Literature Review
Authors: Lin Jia 
Published: May 2019

Abstract
This paper systematically reviews factors related to the use of reading strategies among college-level learners of English as a foreign/second language (EFL/ESL). The author examines empirical studies published from 2000 to 2017 in order to answer two research questions: (a) What factors relate to the college-level EFL/ESL learners’ use of reading strategies? (b) How do these factors relate to college-level EFL/ESL learners’ use of reading strategies? An initial review of the literature identifies four factors related to EFL/ESL learners’ reading strategy use: English proficiency, first language (L1) literacy experience, gender, and motivation. For reasons of space, this article only reports and discusses findings on the first two factors. (1) English proficiency: High-proficiency readers use more metacognitive, support, global, and problem-solving strategies and have more metacognitive knowledge of strategy use than low-proficiency readers. They also differ from low-proficiency readers in learning reading strategies. (2) L1 literacy experience: EFL/ESL readers’ L1 linguistic features and L1 reading experience shape their strategy use when they read English.
Drugs as part of the psychedelic trance dance party
Authors: Kajanová Alena , Mrhálek Tomáš 
Published: May 2019

Abstract
The aim of our paper is to analyze the position the psychedelic trance subculture takes on drug use and whether it applies to prescriptive regulatory systems on drug-taking. A qualitative field research strategy was adopted with the use of semi-structured interviews and participant observations. Actors at three levels of participation in the subculture (experts, long-term participants and newcomers to psychedelic trance parties) were interviewed. The results showed that the subculture distinguishes between tolerated and non-tolerated drugs. This distinction is different from the mainstream paradigm. The subculture also has unwritten rules relating to the behavior expected of an intoxicatedperson. However, there is only limited potential for the subculture to enforce these standards and recognition that this represents a threat. Psychedelic trance stands out from other dance scenes in the use of specific drugs—hallucinogens—that dominate and inform its culture.
Properties of Individual Hippocampal Synapses Influencing NMDA-Receptor Activation by Spontaneous Neurotransmission
Authors: Metzbower Sarah R. , Joo Yuyoung , Benavides David R. , Blanpied Thomas A. 
Published: May 2019

AbstractNMDA receptor (NMDAR) activation is critical for maintenance and modification of synapse strength. Specifically, NMDAR activation by spontaneous glutamate release has been shown to mediate some forms of synaptic plasticity as well as synaptic development. Interestingly, there is evidence that within individual synapses each release mode may be segregated such that postsynaptically there are distinct pools of responsive receptors. To examine potential regulators of NMDAR activation because of spontaneous glutamate release in cultured hippocampal neurons, we used GCaMP6f imaging at single synapses in concert with confocal and super-resolution imaging. Using these single-spine approaches, we found that Ca2+entry activated by spontaneous release tends to be carried by GluN2B-NMDARs. Additionally, the amount of NMDAR activation varies greatly both between synapses and within synapses, and is unrelated to spine and synapse size, but does correlate loosely with synapse distance from the soma. Despite the critical role of spontaneous activation of NMDARs in maintaining synaptic function, their activation seems to be controlled factors other than synapse size or synapse distance from the soma. It is most likely that NMDAR activation by spontaneous release influenced variability in subsynaptic receptor position, release site position, vesicle content, and channel properties. Therefore, spontaneous activation of NMDARs appears to be regulated distinctly from other receptor types, notably AMPARs, within individual synapses.
Išankstinio administracinių ginčų nagrinėjimo ne teisme institutas Lietuvoje: teisinio reguliavimo aiškinimo problematika
Authors: Paškevičienė Laura 
Published: May 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]
Straipsnyje analizuojama Lietuvos teismų praktika, susiklosčiusi išankstinio administracinių ginčų nagrinėjimo ne teisme vertinimo srityje, siekiant patikrinti prielaidą dėl šios jurisprudencijos nenuoseklumo, vertinant administracinių ginčų nagrinėjimą kaip ikiteisminį instituciniu ir funkciniu požiūriu. Autorė stengiasi ištirti, kokios teisės aiškinimo taisyklės yra įtvirtintos šioje jurisprudencijoje ir kokiais teisiniais argumentais asmenų ginčų ir skundų nagrinėjimas konkrečiose administracinėse srityse teismuose kvalifikuojamas ikiteisminiu administracinių ginčų nagrinėjimu, bei įvertinti šios teismų praktikos nuostatų įtaką šio ginčų nagrinėjimo instituto formavimui ir asmens teisės į veiksmingą teisinę gynybą jame apimčiai.
Jungtinių Tautų tikslinės finansinės priemonės: peržiūros procedūrų atitiktis teisės į teisingą procesą standartams
Authors: Steponėnaitė Viltė Kristina 
Published: May 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]
Straipsnyje ginčijama, kad Jungtinės Tautos, nustatydamos individualizuotas finansines ribojančias priemones, privalo veikti suderinamai su fundamentalių žmogaus teisių, konkrečiai – teisės į teisingą procesą – reikalavimais. Atsižvelgiant į tai ir į, kaip ginčijama, aktualias teisės į teisingą procesą garantijas, ginčijama, kad šiuo metu užtikrinami peržiūros mechanizmai tikslinių finansinių ribojančių priemonių adresatams Jungtinių Tautų lygmeniu negali būti laikomi atitinkantys teisės į teisingą procesą reikalavimus, atitinkamai šiuo metu susiklosčiusi padėtis Jungtinių Tautų lygmeniu vertintina kaip nesuderinama su fundamentalių žmogaus teisių reikalavimais.
Tukuh Ciburuy: Sebuah Kajian Étnografi
Authors: Indriani Rini Sri 
Published: May 2019

This research is an ethnographic study to collect cultural data from an ethnic or unique community in Kabuyutan Ciburuy, Kabupaten Garut, West Java Province. Qualitative analysis was carried out to understand Tukuh Ciburuy terminology as revealed by experts or communities outside of Kabuyutan Ciburuy. Whereas documentation and description were used to reveal various customs, taliparanti, or habits in Kabuyutan Ciburuy that represent the attitude or view of the people of Kabuyutan Ciburuy. Based on the results of the research, it can be concluded that in the Kabuyutan Ciburuy tradition, Tukuh Ciburuy means stick to the rules and implement it regularly. Tukuh Ciburuy manifested by Kabuyutan Ciburuy people and Ciburuy Village is in several ways such as in Pantangan and Seba ceremonies. In Kabuyutan Ciburuy tradition, Pantangan is manifested in activities or things that formally prohibit to be done by its society (taboo). These prohibitions have to be obeyed. If it is violated, it is believed that there will be a disaster for the person did it. The Seba ceremony is carried out by holding on the belief that the ceremony was considered an obligatory by the people of Kabuyutan Ciburuy. This belief is based on the assumption of wishful thinking that strong and magical phenomena will arise. If it is obeyed it will avoid the unwanted disaster. Conversely, if it is not fulfilled it will have a negative effect on Ciburuy people daily life.AbstrakPenelitian ini adalah sebuah penelitian etnografi untuk mengumpulkan data kebudayaan sebuah masyarakat etnik atau unik di Kabuyutan Ciburuy, Kabupaten Garut, Provinsi Jawa Barat. Analisis kualitatif dilaksanakan untuk memahami istilah tukuh Ciburuy sebagaimana diungkap oleh para ahli atau masyarakat di luar Kabuyutan Ciburuy. Sedangkan dokumentasi dan deskripsi digunakan untuk mengungkap berbagai adat, tali paranti, atau kebiasaan di Kabuyutan Ciburuy yang merepresentasikan sikap atau pandangan masyarakat Kabuyutan Ciburuy. Berdasarkan hasil penelitian, dapat diambil kesimpulan bahwa dalam tradisi Kabuyutan Ciburuy, tukuh Ciburuy bermakna teguh terhadap aturan-aturan yang harus dilaksanakan secara rutin. Tukuh Ciburuy oleh masyarakat Kabuyutan Ciburuy dan Kampung Ciburuy diwujudkan dalam beberapa hal seperti pantangan dan upacara seba. Dalam tradisi Kabuyutan Ciburuy, pantangan diwujudkan dalam kegiatan-kegiatan atau hal-hal yang tidak boleh dilakukan oleh masyarakatnya. Pantangan-pantangan tersebut tidak boleh dilanggar. Jika dilanggar, dipercaya akan terjadi musibah terhadap orang yang melanggarnya. Upacara seba dilaksankan oleh masyarakat Ciburuy dengan berpegangan pada keyakinan bahwa upacara tradisi dianggap wajib dilaksanakan oleh masyarakat Kabuyutan Ciburuy. Hal tersebut diyakini dengan anggapan bahwa akan timbul hal-hal yang bersipat kuat dan magis. Jika dilaksankan, akan terhindar pula dari berbagai hal yang tidak diinginkan. Sebaliknya, jika tidak dilaksanakan akan menimbulkan akibat buruk bagi kehidupan sehari-hari masyarakat Ciburuy.
PERAN MEDIA SOSIAL TERHADAP GAYA HIDUP SISWA
Authors: Juwita Elsa Puji , Budimansyah Dasim , Nurbayani Siti 
Published: May 2019

Tujuan penelitian ini untuk untuk mengetahui sejauh mana peranan media sosial dapat berpengaruh terhadap gaya hidup remaja di SMA Negeri 5 Bandung. Penelitian ini menggunakan pendekatan kualitatif dan menggunakan metode studi kasus. Simpulan penelitian ini intensitas pengguna media sosial saat ini semakin meningkat. Media sosial digunakan sebagai alat komunikasi maupun hiburan di.kalangan remaja perkotaan. Berkembangnya media sosial memberikan dampak baik positif maupun negatif bagi penggunanya. Pembelajaran sosiologi dapat dimanfaatkan sebagai contoh gaya hidup remaja saat ini sebagai upaya membina karakter remaja dalam menghadapi era globalisasi. Kata kunci : media sosial, gaya hidup, siswa
FENOMENA “KUPU-KUPU ABU-ABU” SEBAGAI BENTUK PENYIMPANGAN SOSIAL PADA KALANGAN REMAJA DI CIANJUR
Authors: Prabowo Andika 
Published: May 2019

Penelitian ini mengupas secara mendalam mengenai fenomena kupu-kupu abu-abu yang menjangkit beberapa remaja siswi di Cianjur. Kupu-kupu abu-abu merupakan sebutan bagi gadis remaja berstatus pelajar yang memiliki perilaku menyimpang dimana mereka sering melakukan hubungan seks diluar nikah dengan kekasihnya ataupun laki-laki yang baru dikenal tanpa menuntut bayaran. Melakukan hubungan seks atas dasar kesenangan menjadikannya pembeda antara kupu-kupu abu-abu dengan WTS (Wanita Tuna Susila) pada umumnya. Berbagai macam faktor melatarbelakangi dimulai dari rendahnya tingkat ekonomi, keluarga tidak harmonis, lingkungan, konsumsi minuman keras, hingga faktor paling mengerikan yaitu para pelaku memiliki kelainan seks yang disebut hypersexual. Maka dari itu gadis kupu-kupu abu-abu dalam melakukan hubungan seks tidak meminta bayaran karena yang mereka cari adalah kepuasan. Kata Kunci : Penyimpangan Sosial, Kupu-kupu Abu-abu.
TRANSFORMASI NILAI-NILAI KEARIFAN LOKAL MASYARAKAT ADAT CIREUNDEU
Authors: Nurhayanto Puji , Wildan Dadan 
Published: May 2019

Masyarakat adat merupakan masyarakat yang memiliki cara hidup tersendiri, cara hidup tersebut disebut kearifan lokal. Era informasi menjadikan masyarakat adat ikut terlibat dalam perubahan agar tidak tergusur oleh perubahan zaman dengan konsekuensi kearifan lokal yang mereka miliki mengalami proses transformasi seperti yang terjadi pada masyarakat adat Cireundeu. Penelitian ini menggunakan pendekatan kualitatif. Data yang dikumpulkan dalam penelitian ini diperoleh melalui wawancara mendalam yang didokumentasikan melalui video. Hasil penelitian menunjukkan bahwa masyarakat adat Cireundeu bersikap terbuka dalam menerima perubahan karena kebutuhan zaman. Kesimpulan dalam penelitian ini berupa kearifan lokal yang dimiliki oleh masyarakat adat Cireundeu mengalami transformasi dalam segi bentuk maupun makna. Kata kunci: transformasi, masyarakat adat Cireundeu, kearifan lokal.
KONTRIBUSI ORANG TUA DALAM PROSES PERGESERAN GAYA HIDUP ANAK
Authors: Astuti Desi , Suryadi Karim , Nurbayani K Siti 
Published: May 2019

Kontribusi orang tua dalam proses pergeseran gaya hidup anak adalah dengan menjadi fasilitator media bermain anak. Selain itu cara orang tua menerapkan pola asuh yang kurang sesuai juga menjadi salah satu penyebab bergesernya gaya hidup anak. Terdapat tiga gaya pola asuh dalam mendidik dan membina anak, yaitu pola asuh gaya otoriter, gaya premisive dan gaya autoritatif. Orang tua tipepremisive merupakan orang tua yang lebih banyak memberikan pengaruh terhadap bergesernya gaya hidup anak dibandingkan dengan orang tua tipe otoriter yang lebih sedikit memberikan pengaruh kepada pergeseran gaya hidup anak, dan juga orang tua yang menerapkan pola asuh autoritatif yang sangat kurang memberikan pengaruh terhadap pergeseran gaya hidup anak. Adapun gaya pola asuh yang cocok diterapkan pada anak di Desa Cimungkal adalah pola asuh gaya autoritatif yang memberikan kesempatan kepada anak untuk berkembang mengikuti zaman namun tetap menuntut anak untuk mengikuti aturan yang ada agar anak tidak terlalu menyimpang dari masa perkembangannya. Penelitian ini dilaksanakan dengan menggunakan pendekatan kualitatif dengan metode deskriptif. Teknik pengumpulan data yang digunakan adalah wawancara, observasi, studi dokumentasi dan studi literatur.
PEMBENTUKAN CITRA TAMAN REKREASI DKI JAKARTA SEBAGAI GREEN CITY MELALUI KUALITAS PENYAMPAIAN JASA DAN VALUECREATION (STUDI PADA PARA PENGUNJUNG TAMAN-TAMAN REKREASI DI DKI JAKARTA)
Authors: Wibowo Lili Adi 
Published: May 2019

Walaupun DKI Jakarta menempati ururtan ke 2 tertinggi sebagai daya saing destinasi pariwisata di Indonesia setelah Bali, namun citra Taman Rekreasi DKI Jakarta sebagai sarana pelestarian lingkungan di wilayah DKI mendapatkan penilaian yang sangat rendah. Rendahnya citra taman rekreasi di DKI Jakarta diduga disebabkan oleh penyampaian kualitas jasa yang meliputi: fasilitas layanan (kelengkapan, kenyamanan fasilitas yang tersedia di obyek wisata sesuai dengan keinginan konsumen) serta layanan personal (sikap dan behavior petugas taman rekreasi dalam memberikan layanan kepada konsumen) dan penciptaan nilai pelanggan (value creation) obyek wisata yang dirasakan pengunjung relatif masih kurang terhadap obyek wisata pesaing. Melalui penelitian ini akan dikaji bagaimana pengaruh kualitas penyampaian jasa dan value creationtaman rekreasi di DKI Jakarta terhadap pembentukan citra taman rekreasi DKI Jakarta sebagai green city. Metode penelitian yang digunakan yaitu metode descriptive dan explanatory survey dengan ukuran sampel sebanyak 480 pada pengunjung taman rekreasi di Jakarta yaitu Taman Mini Indonesia Indah, Taman Impian Jaya Ancol dan Taman Margasatwa Ragunan yang diambil secara proposional melalui wawancara, observasi, angket, serta dokumentasi. Sedangkan teknik analisis data yang digunakan adalah Structural Equation Model dengan program Lisrel. Hasil penelitian menunjukkan bahwa variabel kualitas penyampaian jasa dan value creation memberikan pengaruh yang signifikan kepada pembentukan citra Taman Rekreasi DKI Jakarta sebagai Green City. Faktor pembentuk terbesar dari pembentukan citra Taman Rekreasi DKI Jakarta dipengaruhi oleh variabel value creation dibandingkan kulitas jasa pelayanan. Temuan empirik yang menarik lainnya bahwa faktor pembentuk kualitas pelayanan mendapatkan penilaian positif seperti memiliki keunggulan konsep yang unik, menarik, mudah dikenal, memberikan pengalaman, berpotensi besar untuk dikunjungi wisnus dan wisman, memiliki karyawan yang dapat memberikan informasi yang dibutuhkan. Sedangkan penilaian negatif berupa pengaturan fasilitas kurang memudahkan pengunjung menemukan apa yang dibutuhkan, tidak memberikan kenyaman untuk dikunjungi oleh orang tua perhatian karyawan secara individu dirasakan kurang dan fasilitas-fasilitas khusus (information center, penjaga pantai, tempat belanja yang nyaman, dan lain-lain) dirasakan kurang. Pada variabel value creation ditemukan bahwa faktor keamanan dan kemudahan menjangkau taman rekreasi perlu mendapatkan perhatian dari pengelola. Sedangkan citra taman rekreasi yang tertanam di benak pengunjung, apabila taman rekreasi dapat menciptakan kepuasan melalui kualitas layanan yang diberikan dan kejelasan identitas taman rekreasinya.