bluuebunny/crossref_metadata_2025_split huggingface dataset:
Halide‐Diffusion‐Assisted Perovskite Lamination Process for Semitransparent Perovskite Solar Cells
Authors: Cheng Jian , Kim Wooyeon , Choi In , Yu Subin , Koo Bonkee , Ko Min Jae 
Published: November 2024

AbstractSemitransparent perovskite solar cells (PSCs) efficiently absorb light from both front and rear sides under illumination, and hence, PSCs have the potential for use in applications requiring bifacial or tandem solar cells. A facile method to fabricate semitransparent PSCs involves preparing a perovskite (PVSK) film on two transparent substrates and then laminating the substrates together. However, realizing high‐performance laminated semitransparent PSCs is challenging because the imperfect contact at the PVSK interlayer results in void formation and partial degradation of PVSK. To address this issue, a halide‐diffusion‐assisted lamination (HDL) method is proposed. In the method, a controlled halide concentration gradient is used to effectively laminate the top and bottom PVSK layers. Semitransparent PSCs prepared through the HDL method (hereafter referred to as HDL‐PSCs) exhibited a power conversion efficiency (PCE) of 18.93%. In particular, an HDL‐PSC exhibited higher thermal stability, maintaining its initial PCE for over 1200 h at 85 °C.
How the Kinetic Balance Between Charge‐Transfer and Mass‐Transfer Influences Zinc Anode Stability: An Ultramicroelectrode Study
Authors: Rana Ashutosh , Faisal Md. Arif , Roy Kingshuk , Nguyen James H. , Paul Saptarshi , Dick Jeffrey E. 
Published: November 2024

AbstractAqueous zinc‐metal batteries (AZMBs) represent a promising frontier in battery technology, offering sustainable and safe alternatives to traditional non‐aqueous batteries. Despite their potential, understanding the kinetics of zinc electrodeposition—a critical factor in AZMB performance—remains underexplored. Utilizing voltammetry on ultramicroelectrodes, we investigate how scan rate influences key processes of nucleation and growth during Zn2+ electrodeposition. The findings highlight the efficacy of the Butler‐Volmer formulation in capturing electron‐transfer kinetics, contrasting with complex electron transfer kinetic models used for non‐aqueous battery chemistries. We clearly demonstrate that there is a strong dependence of scan rate on the measured value of kinetic parameters (exchange current). To accurately probe the charge transfer kinetics, it is essential to apply fast scan voltammetry to decouple the influence of mass transfer, ensuring that the measured current is independent of the scan rate. Furthermore, by studying a model electrolyte additive, the intricate balance between charge transfer and mass transfer dynamics is unveiled, and this information is crucial for enhancing the stability of zinc metal anodes. These insights pave the way for developing advanced electrolyte and current collector formulations, promising enhanced cyclability and sustainability in zinc metal batteries.
Development of UHPLC‐MS/MS Method for Evaluation of the Acute Oral Toxicity and Pharmacokinetics of Ursodeoxycholic Acid and Silymarin Combination in Rats
Authors: Hammam Mennatallah A. , Zakaria Zainab , Rabee Mahmoud , Rabea Al‐Taher , Hafez Donia E. , Abdel‐Halim Mohammad , Ismail Ahmed Ibrahim , El‐Sayed Mansy Azza 
Published: November 2024

ABSTRACTThe combination of ursodeoxycholic acid (UDCA) and silymarin has been shown to alleviate various hepatic conditions. This study aimed to evaluate the acute oral toxicity and in vivo pharmacokinetics of the combination in female Sprague Dawley rats. The acute oral toxicity and the pharmacokinetic studies were conducted using 17 rats divided into five groups and 30 rats assigned into four control groups and one treatment group, respectively. A new UHPLC/MS‐MS method was applied to determine silibinin (SIL) and UDCA in plasma, urine, and feces. This method used the BEH C8 column (1.7 µm, 100 × 2.1 mm) with a gradient elution of 0.01% formic acid in water and 0.01% formic acid in acetonitrile. The acute oral toxicity study revealed that administering the combination at 5000 mg/kg preserves a wide safety margin. In the pharmacokinetic study, the combination resulted in a significant enhancement of the absorption of both drugs and a reduction of the renal elimination of silymarin. The oral LD50 of the combination was higher than 5000 mg/kg, so according to the OECD guidelines, it was classified in Category 5 GHS. The presented data serve as scientifically defensible safety data with a defined absorption and elimination profile for the combination.
Autocorrelated Errors in Panel Linear Regression: A New Objective Bayesian Perspective
Authors: Xie Haifan , Xie Yunlang , Yu Pengyi 
Published: November 2024

ABSTRACTA challenge to the estimation and inference of panel linear regression models consists in the uncertainty associated with the unknown autocovariance of errors. For an improved quantification of this uncertainty particularly in the context of wide panels, the study derives an objective Bayesian posterior of the interested coefficients where the unknown autocovariance of errors is marginalized out. Due to the intractability of the posterior's normalizing constant, estimation and inference rely on the Monte Carlo samples generated from the No‐U‐Turn Sampler algorithm. Theoretic works show that the proposed Bayesian method approaches the properties of generalized least squares (GLS) asymptotically. Simulation tests reveal that the Bayesian method performs closer to GLS compared to other frequentist methods, achieving a relatively reasonable balance between robustness and efficiency. For a real application, the Bayesian method is extended to the case of unbalanced panel and then compared with other methods in examining the ambiguous relation between CEO duality and financial performance. Finally, limitations of the current study and recommendations for the future research are discussed.
Co‐Administration of a Plantain‐Based Diet and Quercetin Modulates Atrazine‐Induced Testicular Dysfunction in Rats via Testicular Steroidogenesis and Redox‐Inflammatory Processes
Authors: Rotimi Damilare Emmanuel , Elekofehinti Olusola Olalekan , Oluba Olarewaju Michael , Adeyemi Oluyomi Stephen 
Published: November 2024

ABSTRACTPlantain has been reported to enhance testicular function indices, however, the mechanism remains unknown. The present study investigated the action mechanisms of a plantain‐based diet in the treatment of rat testicular dysfunction caused by exposure to atrazine (ATZ). The rats were grouped into 10 groups (5 rats each); control group, 50% plantain‐based diet (50% PBD), 25% PBD, 12.5% PBD, quercetin (QUE), ATZ only, 50% PBD + ATZ, 25% PBD + ATZ, 12.5% PBD + ATZ, and QUE + ATZ for 21 days. Results revealed that ATZ treatments in rats lowered gonadal hormone levels and the semen quality (sperm concentration, motility, count, and viability), damaged testicular morphology and functions, and impaired redox‐inflammatory balance as well as cholinergic and purinergic activities. However, treatment with PBD and QUE ameliorated the testicular toxicity induced by ATZ, although the treatment did not improve the rat semen quality. In addition, the ATZ + QUE and QUE groups showed mild to moderate atrophic degenerative changes, with reduced spermatogenic activity. Together, the results are evidence that 21 days of exposure to ATZ impaired testicular function. However, co‐administration of atrazine and PBD improves rat gonadal hormones, redox state, inflammatory indices, cholinergic, and purinergic activities, as well as histoarchitecture of the testes.
Enhancing prediction accuracy of grain yield in wheat lines adapted to the southeastern United States through multivariate and multi‐environment genomic prediction models incorporating spectral and thermal information
Authors: McBreen Jordan , Babar Md. Ali , Jarquin Diego , Khan Naeem , Harrison Steve , DeWitt Noah , Mergoum Mohamed , Lopez Ben , Boyles Richard , Lyerly Jeanette , Murphy J. Paul , Shakiba Ehsan , Sutton Russel , Ibrahim Amir , Howell Kimberly , Smith Jared H. , Brown‐Guedira Gina , Tiwari Vijay , Santantonio Nicholas , Van Sanford David A. 
Published: November 2024

AbstractEnhancing predictive modeling accuracy in wheat (Triticum aestivum) breeding through the integration of high‐throughput phenotyping (HTP) data with genomic information is crucial for maximizing genetic gain. In this study, spanning four locations in the southeastern United States over 3 years, models to predict grain yield (GY) were investigated through different cross‐validation approaches. The results demonstrate the superiority of multivariate comprehensive models that incorporate both genomic and HTP data, particularly in accurately predicting GY across diverse locations and years. These HTP‐incorporating models achieve prediction accuracies ranging from 0.59 to 0.68, compared to 0.40–0.54 for genomic‐only models when tested under different prediction scenarios both across years and locations. The comprehensive models exhibit superior generalization to new environments and achieve the highest accuracy when trained on diverse datasets. Predictive accuracy improves as models incorporate data from multiple years, highlighting the importance of considering temporal dynamics in modeling approaches. The study reveals that multivariate prediction outperformed genomic prediction methods in predicting lines across years and locations. The percentage of top 25% lines selected based on multivariate prediction was higher compared to genomic‐only models, indicated by higher specificity, which is the proportion of correctly identified top‐yielding lines that matched the observed top 25% performance across different sites and years. Additionally, the study addresses the prediction of untested locations based on other locations within the same year and in new years at previously tested locations. Findings show the comprehensive models effectively extrapolate to new environments, highlighting their potential for guiding breeding strategies.
Validation of a reduction in time for avian influenza virus isolation using specific pathogen‐free embryonated chicken eggs
Authors: Reid Scott M. , Coward Vivien J. , James Joe , Hansen Rowena D. E. , Birch Colin , Bakrania Mayur , Brookes Sharon M. , Brown Ian H. , Banyard Ashley C. 
Published: November 2024

AbstractBackgroundThe international gold standard for avian influenza virus (AIV) diagnosis is virus isolation (VI) in specific pathogen‐free embryonated chicken eggs (ECEs). AIV isolation typically involves a 6‐day turnaround, during which premises under suspicion for notifiable AIV infection are held under restriction regardless of molecular diagnoses, often with significant welfare implications.MethodsA reduction in time for negation by VI was investigated following experimental inoculation of AIV from known‐positive original clinical material into ECEs. VI data derived from more than 600 case investigations from epizootics of high‐pathogenicity AIV (HPAIV) in Great Britain since 2016 and from low‐pathogenicity AIV (LPAIV) cases in Great Britain since 2014 were examined to support a reduction in test timing using alternative regimens.ResultsHPAIVs were isolated during the first passage, and for LPAIV VI, the second passage could be reduced to 2 days. Power analysis showed that the benefit of reducing the number of days outweighed the risk of missing a positive isolate.LimitationsLimited data were available from experimental inoculations.ConclusionThis truncated methodology, which enables an earlier release of restrictions, may substantially ease the economic implications of restriction. It could also reduce bird welfare implications and improve international standards without loss of test performance.
Cyclophosphamide-induced testicular injury: the role of chrysin in mitigating iron overload and ferroptosis
Authors: Saleh Dalia O. , Abo El Nasr Nesma M. E. , Hussien Yosra A. , El-Baset Marawan Abd , Ahmed Kawkab A. 
Published: November 2024

AbstractThis study evaluated the beneficial effects of chrysin against cyclophosphamide (CP)-induced testicular toxicity in rats across several parameters, including hormones, oxidative stress, inflammation, apoptosis, and protein expression. Rats were pretreated with oral doses of chrysin at 25, 50, or 100 mg/kg daily for 7 days. On the 8th day, all groups except controls received CP (200 mg/kg) injection. Chrysin doses continued for 7 more days. Hormones, oxidative stress markers, inflammatory cytokines, apoptosis regulators, and iron regulatory proteins were assessed. CP decreased testosterone, inhibin B, GSH, and GPx4 and increased FSH, cholesterol, MDA, IL-6, and BAX. It also drastically reduced TfR1, liprin, and IREB2. Chrysin dose-dependently counteracted these effects. The highest 100 mg/kg chrysin dose increased testosterone, inhibin B, GSH, GPx4, BCL2, TfR1, liprin, and IREB2 while decreasing FSH, cholesterol, MDA, IL-6, and BAX close to control levels. There were also significant incremental benefits for testosterone, inhibin B, and other parameters with higher chrysin doses. Chrysin dose-dependently attenuated CP-induced hormonal dysfunction, oxidative stress, inflammation, apoptosis, and iron-regulatory protein suppression. The maximum dose showed the most optimal protective effects in restoring the testicular toxicity markers. These results validate the promising spermatoprotective properties of chrysin against chemotherapeutic germ cell damage.
Antioxidant interaction between α-tocopherol and quercetin in homogeneous solutions of peroxidating methyl linoleate
Authors: Becker Eleonora Miquel , Jørgensen Søren S. , Andersen Mogens L. , Skibsted Leif H. 
Published: November 2024

Abstract
Interaction between α-tocopherol and quercetin as antioxidants was studied by quantification of both compounds in air-saturated tert-butyl alcohol as a hydrogen-bonding solvent during oxidation of dissolved methyl linoleate initiated by lipophilic α,α´-azobis-isobutyronitrile (AIBN) at 50 °C. The main question of the study was, if α-tocopherol and quercetin regenerate each other from their one-electron oxidized radical forms when they both are present during lipid autoxidation. α-Tocopherol with an initial concentration of 0.14 mM was by HPLC-analysis found to be depleted first, indicating that α-tocopherol is a more effective antioxidant. The concentration of quercetin, also initially 0.14 mM as followed spectrophotometrically, remained constant until α-tocopherol was consumed. The rate of α-tocopherol depletion was found to be independent of the presence of quercetin. Cyclic voltammetry showed that α-tocopherol is more easily oxidized than quercetin. Quercetin has previously been reported to regenerate the more reducing α-tocopherol during oxidation of lipid substrates in polar hydrogen-bonding solvents based on measured oxygen consumption rates. Our results further indicate that regeneration reactions between α-tocopherol and quercetin as antioxidants are of little if any importance, most likely due to the low extent of quercetin oxidation when they both are present. This conclusion was further supported by simulation of time profiles, from which an upper limit of 400 M−1·s−1 was estimated for the second-order rate constant for α-tocopherol regeneration of quercetin.
Offspring’s early-life performance varies with father’s sperm quality in a genetically monogamous seabird
Authors: Manas Frédéric , Pineaux Maxime , Humann-Guilleminot Ségolène , Hatch Scott A. , Blanchard Pierrick , Leclaire Sarah 
Published: November 2024

AbstractAlthough the effect of sperm quality is well studied in the context of sperm competition, its effect on offspring performance, especially after the embryo stages, has been less investigated. Here, we investigated whether the proportion of spermatozoa with normal morphology was associated with offspring performance during chick development in the black-legged kittiwake, a behaviorally and genetically monogamous seabird in which sperm competition is absent. First, we found that, at hatching, the difference in body condition between the first- and second-hatched siblings was higher when the father had a lower proportion of normal spermatozoa. We discuss this result in light of maternal allocation strategy to manipulate sibling competition. Second, we showed that, in first-hatched chicks, body mass growth between hatching and the age of 10 days, body condition at the age of 10 days and maximum body mass reached before fledging were positively related to the proportion of normal spermatozoa in the father’s sperm. Overall, our results support the role of sperm quality on offspring performance in the black-legged kittiwake and call for further studies investigating the importance of sperm quality in genetically monogamous species.
A Note on Asymmetric Hypergraphs
Authors: Bohnert Dominik , Winter Christian 
Published: November 2024

AbstractA k-graph $$\mathcal {G}$$
G
is asymmetric if there does not exist an automorphism on $$\mathcal {G}$$
G
other than the identity, and $$\mathcal {G}$$
G
is called minimal asymmetric if it is asymmetric but every non-trivial induced sub-hypergraph of $$\mathcal {G}$$
G
is non-asymmetric. Extending a result of Jiang and Nešetřil (J Comb Theory Ser B 164: 105–118, 2024), we show that for every $$k\ge 3$$

k
≥
3

, there exist infinitely many minimal asymmetric k-graphs which have maximum degree 2 and are linear. Further, we show that there are infinitely many 2-regular asymmetric k-graphs for $$k\ge 3$$

k
≥
3

.
Video laryngoscopy in neonate and infant intubation—a systematic review and meta-analysis
Authors: Kuitunen Ilari , Räsänen Kati , Huttunen Tuomas T. 
Published: November 2024

Abstract
We aimed to analyze the effect of video laryngoscopy on intubation success, time to intubation, and adverse events in infants and neonates. A systematic review and meta-analysis was performed, for which a neonates (age less than 29 days) and infants (age less than 365 days) needing to be intubated were included. The main outcomes were first attempt success rate in the intubation, time to intubation, and adverse events. Evidence certainty was assessed according to GRADE. We included 13 studies. Seven studies with 897 patients focused on neonates, and the first attempt success rate was higher in the video laryngoscopy group (RR 1.18, CI: 1.03–1.36). Six studies included 1039 infants, and the success rate was higher in the video laryngoscopy group (RR 1.06, CI: 1.00–1.20). Time to intubation was assessed in 11 trials, and there was no difference between the groups (mean difference 1.2 s, CI − 2.2 s to + 4.6 s). Odds of desaturation (OR 0.62, CI 0.42–0.93) and nasal/oral trauma (OR 0.24, CI 0.07–0.85) were lower in the video laryngoscopy group. Evidence certainties varied between moderate and low.

Conclusion: We found moderate certainty evidence that the use of video laryngoscopy improves first attempt success rates in neonate and infant intubations, while the time to intubation did not differ between video and direct laryngoscopy groups. Further studies are still needed to improve the first intubation success rates in neonates.

What is known:
• Video laryngoscopy has been shown to improve first-pass intubation success rates and reduce time to intubation in adults and older children.
What is new:
• Video laryngoscopy improved the first attempt intubation success rates both in neonates and in infants.
• Video laryngoscopy did not increase the time to intubation, and it was associated with less adverse events than direct laryngoscopy.
Trophic generalism in the winter moth: a model species for phenological mismatch
Authors: Weir Jamie C. 
Published: November 2024

AbstractClimate change has the potential to disrupt phenological synchrony among interacting species that vary in their phenological sensitivity to temperature. The phenological synchrony observed between winter moth Operophtera brumata caterpillars and oak leafing in spring has become an emblematic test case of this phenomenon, with caterpillars seemingly advancing their phenology more than their host-plant. However, work on this trophic interaction—and on phenological mismatch more widely—routinely overlooks the potential for trophic generalism to buffer the negative effects of mismatch. In the largest study of its kind—using over 3500 individuals reared from egg to pupa—I tested the performance of winter moth caterpillars from four UK populations across nine host-plant species, and considered how adaptation to locally abundant host-plants may modulate performance in different populations. I found that caterpillars survive and grow well across a range of host-plant species, with some evidence of a host-plant by population interaction in performance. Contrary to widespread assumptions, oak seems a relatively poor host-plant species. Occupying a broad trophic niche may help consumers like the winter moth exploit a narrow phenological niche, whereby phenological variation among host-plant species buffers them against asynchrony with any one particular host-plant species. Determining the significance of trophic generalism in the ecology of consumers is a crucial first step towards assessing its role as a potential buffering mechanism and, hence, evaluating the true threat posed by mismatch.
Incidence and impact of food aversions among patients with cancer receiving outpatient chemotherapy: a one-year prospective survey
Authors: Suka Machi , Katsube Atsushi , Fujimoto Reiko , Uwagawa Tadashi , Shimada Takashi , Yano Shingo , Yamauchi Takashi , Yanagisawa Hiroyuki 
Published: November 2024

Abstract
Purpose
To determine the current incidence and impact of chemotherapy-associated food aversions in a variety of cancer types.

Methods
Cancer patients aged 18 years and older who received chemotherapy infusions at the outpatient chemotherapy unit of a university hospital between May 2022 and April 2023 were included in the study (n = 243). To monitor the occurrence of food aversions, participants were asked to complete a food preference questionnaire each time they visited the outpatient chemotherapy unit.

Results
During the one-year survey period, one in four cancer patients receiving outpatient chemotherapy developed food aversions, and one in four of them complained of interference with daily life due to eating problems at the same time or later. The median time to the onset of food aversion was 46 (interquartile range 36–77) days after the start of chemotherapy. The incidence of food aversions was significantly higher in patients who were women, had a digestive, gynecologic, or breast cancer, and received more cytotoxic agents in chemotherapy. Patients who developed food aversions tended to lose more body weight than those who did not.

Conclusion
Food aversions were still common among cancer patients undergoing chemotherapy. Even an aversion to a single food may have affected the patient’s nutritional status. Healthcare professionals should closely monitor the occurrence of food aversions, especially in the early days of chemotherapy induction, to detect an increasing risk of malnutrition.

Trial registration
Not applicable.