bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-Occupancy Evaluation of a Crisis Shelter Garden and Application of Findings Through the Use of a Participatory Design Process
Authors: Lygum Victoria L. , Poulsen Dorthe V. , Djernis Dorthe , Djernis Hanne G. , Sidenius Ulrik , Stigsdotter Ulrika K. 
Published: November 2018

Objective: This study concerned optimization of an evidence-based crisis shelter garden as a setting for everyday activities and nature-based therapy. The study hereby tested the design guidelines that the garden is based on. Background: Design guidelines for gardens intended to support health are becoming increasingly specialized, targeting different user groups. This study contributes to the knowledge concerning health-supporting garden design at crisis shelters for women and children who are exposed to domestic violence. Method: The study included a post-occupancy evaluation (POE) consisting of landscape analyses, observation of physical traces, and interviews as well as a subsequent participatory design process. Results: The landscape analyses and the observation of physical traces indicated a minimal level of maintenance and recurrent use being limited to a few areas of the garden. The interviews added nuance and new issues to these results, resulting in the following themes: maintenance, accessibility, safety, therapeutic setting and free space, many ways to play, and social and private spheres. The participatory design process led to an optimization of the garden, including changes to its physical design related to making the garden safer, positively distractive, and more versatile in terms of activities. Improvements were also made regarding policy for use, maintenance, and informing users. Conclusion: The design guidelines were tested, and the evidence was strengthened, adding nuance and new issues to consider during further development of the guidelines. Both the POE and the participatory design process were confirmed as crucial aspects of evidence-based health design.
Renal cell carcinoma in Ireland: rising mortality and survival
Authors: Yap Lee Chien , Leonard Frank , Cullen Ivor , Daly Padraig 
Published: November 2018

Objective: The objective of this study was to evaluate the rising trend in the incidence and mortality of renal cell carcinoma in Ireland. Methods: Data from the National Cancer Registry of Ireland on primary adenocarcinomas of the kidney from 2003 to 2013 were evaluated. Statistical analysis was performed on the data using IBM SPSS statistics V24 software package and Microsoft Excel Software. Results: There were 3801 cases of adenocarcinoma of the kidney with 29% of tumours (n=1103) being found incidentally. The age-adjusted incidence rate of renal cell carcinoma in 2003 was 4.66 per 100,000 women and 8.78 per 100,000 men. These figures have risen to 5.78 and 13.14 in 2013, respectively. There was an annual percentage change of +2.2% for women and +4.1% for men from the years 2003 to 2013. For both sexes the age-standardised all-cause mortality rate for renal adenocarcinoma increased from 1.07 per 100,000 in 2003 to 4.32 ± 0.06 per 100,000 in 2013, an annual percentage change of +15%. Age-adjusted mortality rates in the female population in Ireland increased from 0.78 to 2.66, an annual percentage change of +13.1% and from 1.41 to 6.04 in men, an annual percentage change of +15.8%. Conclusion: There is a paradox emerging in Ireland, with both rising survival rates for renal cell carcinoma and rising mortality rates. While the increased incidence of renal cell carcinoma in Ireland can be attributed somewhat to the increased use of various imaging modalities, it may also be attributed to the significant rise in modifiable risk factors as seen in other developed countries, namely hypertension, obesity, and smoking. Level of evidence: 2c
360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity
Authors: Butler Joseph S. , Lui Darren F. , Malhotra Karan , Suarez-Huerta Maria L. , Yu Haiming , Selvadurai Susanne , Agu Obiekezie , Molloy Sean 
Published: November 2018

Study Design: Retrospective cohort study. Objective: To assess both implant performance and the amount of correction that can be achieved using multilevel anterior lumbar interbody fusion (ALIF). Methods: Retrospective cohort study (n = 178) performed over a 4-year period. Surgical variables examined included blood loss, operative time, perioperative complications, and secondary/revision procedures. Follow-up radiographic assessment was performed to record implant-related problems. Radiographic parameters were examined pre- and postoperatively. Health-related quality of life (HRQOL) outcome measures were collected preoperatively and at 6 weeks, 6 months, 1 year, and 2 years postoperatively. Descriptive and comparative statistical analysis, using paired-sample t test and repeated-measures analysis of variance (rANOVA), was performed. Results: Lumbar lordosis increased from 42° ± 17° preoperatively to 55° ± 11° postoperatively ( P < .001). The visual analog scale back pain mean score improved from 8.3 ± 1.5 preoperatively to 2.6 ± 2.4 at 2 years ( P < .001). The mean Oswestry Disability Index improved from 69.5 ± 21.5 preoperatively to 19.9 ± 15.2 at 2 years ( P < .001). The EQ-5D mean score improved from 0.2 ± 0.2 preoperatively to 0.8 ± 0.1 at 2 years ( P = .02). There were no neurological, vascular, or visceral approach–related injuries reported. No rod breakages and no symptomatic nonunions occurred. There was one revision procedure performed for fracture. Conclusions: The use of porous tantalum cages as part of a 360-degree fusion to treat adult degenerative spinal deformity has been demonstrated to be a safe and effective strategy, leading to good clinical, functional, and radiographic outcomes in the short term.
Identification and characterization of early photoreceptor cis-regulatory elements and their relation to Onecut1
Authors: Jean-Charles Nathalie , Buenaventura Diego F. , Emerson Mark M. 
Published: November 2018

Abstract
Background
Cone and rod photoreceptors are two of the primary cell types affected in human retinal disease. Potential strategies to combat these diseases are the use of gene therapy to rescue compromised photoreceptors or to generate new functional photoreceptors to replace those lost in the diseased retina. Cis-regulatory elements specific to cones, rods, or both types of photoreceptors are critical components of successful implementation of these two strategies. The purpose of this study was to identify and characterize the cell type specificity and activity of cis-regulatory elements active in developing photoreceptors.

Methods
Cis-regulatory elements were introduced into the developing chicken and mouse retina by electroporation. Characterization of reporter activity in relation with cell type markers was determined using confocal microscopy. In addition, two high-throughput flow cytometry assay were developed to assess whether these elements were downstream of Onecut1 in the photoreceptor specification network.

Results
The majority of cis-regulatory elements were active in both cone and rod photoreceptors and were largely uninfluenced by a Onecut1 dominant-negative construct. Elements associated with the Thrb, Nr2e3, and Rhodopsin genes showed highly enriched activity in cones or rods, and were affected by interference in Onecut1 signaling. Rhodopsin promoter activity was the most highly influenced by Onecut1 activity and its induction could be modulated by the Maf family transcription factor L-Maf. Nr2e3 elements were observed to have activity in cone photoreceptors and Nr2e3 protein was expressed in developing cone photoreceptors, suggesting a role for this predominant rod gene in cone photoreceptor development.

Conclusions
The analysis presented here provides an experimental framework to determine the specificity and strength of photoreceptor elements within specific genetic networks during development. The Onecut1 transcription factor is one such factor that influences the gene regulatory networks specific to cones and rods, but not those that are common to both.
3D vertical seismic profile acquired with distributed acoustic sensing on tubing installation: A case study from the CO2CRC Otway Project
Authors: Correa Julia , Pevzner Roman , Bona Andrej , Tertyshnikov Konstantin , Freifeld Barry , Robertson Michelle , Daley Thomas 
Published: November 2018

Distributed acoustic sensing (DAS) can revolutionize the seismic industry by using fiber-optic cables installed permanently to acquire on-demand vertical seismic profile (VSP) data at fine spatial sampling. With this, DAS can solve some of the issues associated with conventional seismic sensors. Studies have successfully demonstrated the use of DAS on cemented fibers for monitoring applications; however, such applications on tubing-deployed fibers are relatively uncommon. Application of tubing-deployed fibers is especially useful for preexisting wells, where there is no opportunity to install a fiber behind the casing. In the CO2CRC Otway Project, we acquired a 3D DAS VSP using a standard fiber-optic cable installed on the production tubing of the injector well. We aim to analyze the quality of the 3D DAS VSP on tubing, as well as discuss lessons learned from the current DAS deployment. We find the limitations associated with the DAS on tubing, as well as ways to improve the quality of the data sets for future surveys at Otway. Due to the reduced coupling and the long fiber length (approximately 20 km), the raw DAS records indicate a high level of noise relative to the signal. Despite the limitations, the migrated 3D DAS VSP data recorded by cable installed on tubing are able to image interfaces beyond the injection depth. Furthermore, we determine that the signal-to-noise ratio might be improved by reducing the fiber length.
Left-right asymmetry in heart development and disease: forming the right loop
Authors: Desgrange Audrey , Le Garrec Jean-François , Meilhac Sigolène M. 
Published: November 2018

ABSTRACT
Extensive studies have shown how bilateral symmetry of the vertebrate embryo is broken during early development, resulting in a molecular left-right bias in the mesoderm. However, how this early asymmetry drives the asymmetric morphogenesis of visceral organs remains poorly understood. The heart provides a striking model of left-right asymmetric morphogenesis, undergoing rightward looping to shape an initially linear heart tube and align cardiac chambers. Importantly, abnormal left-right patterning is associated with severe congenital heart defects, as exemplified in heterotaxy syndrome. Here, we compare the mechanisms underlying the rightward looping of the heart tube in fish, chick and mouse embryos. We propose that heart looping is not only a question of direction, but also one of fine-tuning shape. This is discussed in the context of evolutionary and clinical perspectives.
Typification of Pinus torreyana Parry ex Carrière (Pinaceae) revisited
Authors: Wahlert Gregory A. 
Published: November 2018

AbstractThe name Pinus torreyana Parry ex Carrière has a convoluted nomenclatural history and a somewhat problematic typification. In this paper, the history surrounding the naming of P. torreyana Parry ex Carrière is briefly reviewed and the previous lectotypification is corrected to a neotypification. In addition, Pinus torreyana Parry ex Carrière and P. torreyana Parry ex Torr. are second‐step neotypified and lectotypified on the same specimen, respectively, resulting in the two names being treated as isonyms. Because Carrière’s description of Torrey pine is limited to the characteristics of seed and cone, where the measurements of the cone appear to be in error, P. torreyana is epitypified on a new collection from the type locality, which includes mature female cones. The disposition of three recently discovered duplicate specimens of the neotype of Pinus lophosperma Lindl. is clarified.
O conceito de fenômeno no jovem Heidegger
Authors: López Francisco De Lara 
Published: November 2018

Tradução de "El concepto de fenómeno en el joven Heidegger".O presente trabalho é uma discussão do conceito de fenômeno tal como este se encontra determinado na filosofia do jovem Heidegger. Com ela, pretende-se ir à base que permite elucidar em que sentido este faz fenomenologia ou, em outras palavras, qual ideia de fenomenologia se encontra expressada sob o título de hermenêutica fenomenológica. Em consonância com a leitura do conceito de fenômeno como conceito filosófico, isto é, como indicação formal, nos perguntaremos: 1) como se leva em consideração aquilo que é investigado fenomenologicamente; 2) como se deve aparecer aquilo que é assim investigado; e 3) se, de fato, o conceito de fenômeno funciona sempre em Heidegger como uma indicação formal ou se não se pode constatar nele uma certa ambiguidade.NdT: Este texto foi publicado originalmente na Eidos: Revista de Filosofía de la Universidad del Norte (ISSN: 1692-8857), n° 8, Barranquilla, maio de 2008, pp. 234-256. Tradução de Deborah Moreira Guimarães
Distribusi Nematoda Pucuk Putih Padi Aphelenchoides besseyi di Pulau Jawa
Authors: Diana Didiet Rahayu 
Published: November 2018

Distribution of Rice White Tip Nematode Aphelenchoides besseyi in Java Island Aphelenchoides besseyi is one of the most important rice seed borne nematode causing white tip disease in Indonesia. The status of A. besseyi is considered as quarantine pest category A2, with limited distribution area in Java, Sumatera, and South Kalimantan). The aim of this research was to detect and identify A. besseyi from rice seed based on morphological, morphometry and molecular approaches and to determine its distribution in rice growing areas in Java. Rice seed samples, consisting of 26 varieties, were obtained from seed producers, seed distributors, and farmers in Java. Nematode extraction was done using Baermann method. Molecular identification was carried out by polymerase chain reaction and followed by DNA sequencing and nucleotide analysis. A. besseyi was detected from 74.32% of seed samples. A. besseyi was confirmed to be distributed in Lebak, Bogor, Sukabumi, Subang, Indramayu, Klaten, Sragen, Sukoharjo, Boyolali, Pati, Pemalang, Yogyakarta Sleman, Magetan, Blitar, Tuban, Gresik, Nganjuk, and Banyuwangi. Further nucleotide analysis showed that A. besseyi isolates from rice seed cv Ciherang (Yogyakarta) and cv IR 64 (Banyuwangi) have 99% homology to those from India, China, USA; and 98% homology to those from Taiwan.
LEGAL PERSPECTIVE ON ASEAN ECONOMIC COMMUNITY
Authors: Hartono Darminto , Hardiwinoto Soekotjo 
Published: November 2018

Since 2015, the ASEAN Economic Community (AEC) applied in its member countries, Including Indonesia. The preparation effort is regulatory legislation related to the AEC as a guide to achieve country's goals. The research aims to focus on how to inventory of the AEC regulations and how to find out in passing the AEC. The method uses the normative juridical approach and qualitative descriptive data analysis method. These research results that have a global market share, exporting country, investment destination country, a liberalization of ASEAN goods trade, large demographic bonuses, open services sector, aand smoother capital flows constantly. While the challenge is the elevation of the rate of export-import and the inflation rate, the negative impact of broader capital flows, the similarity of export products Which is still diverse must be solved. The Indonesian Government has an authority to regulate the role and function through it policies optimally, because of the opportunities and the existence of Indonesia. It is a matter of course that each member country to face AEC still not enough of expectations.
PENAL MEDIATION OF TREATMENTS FOR CHILDREN IN THE JUVENILE JUSTICE SYSTEM
Authors: Cahyaningtyas Irma 
Published: November 2018

The protection of children becomes the responsibility of all parties, namely family, community and government. Indonesia through the Act No. 11 Year 2012 on Juvenile Justice System provides protection namely diversion which should be emphasized as a penal mediation which can be used to solve a juvenile cases. There are two main problems; firstly, how is the penal mediation process in the juvenile justice system; secondly, how is the implementation of the penal mediation which is based on Pancasila? The research method used in this paper was normative juridical research method. The approach used in this study is socio legal approach and the data analysis method used a qualitative analysis. The results that in penal mediation in the juvenile cases namely diversion aims to achieve restorative justice. The diversion process is very important and must involve the parties in order the mediation be effective. This process is what distinguishes from the treatments of juvenile’s cases before Act No. 11 Year 2012. In the previous times, penal mediation was not acknowledged so law enforcement procedure is always ends at Juvenile court. Penal mediation in juvenile justice system must be based on Pancasila as the philosophical foundation of Indonesia, which means diversion process must be in accordance with the values of Pancasila, which are are religious moral values; humanistic values; nationalistic values, democratic, and social justice.
Efektifitas Ceramah Booklet dan Buzz Group dalam Upaya Pencegahan Pneumonia pada Anak
Authors: Nababan Sudarwati , Agushybana Farid , Suryoputro Antono 
Published: November 2018

Background: In 2016 Kopeta Health Center was ranked the 4th highest number of cough disease not pneumonia and pneumonia cases from 23 Puskesmas in Sikka District. Health education on pneumonia in this health center has often been conducted, but it seems that the results have not been effective in improving the knowledge of mothers. This is due to the fact that it is only prioritized for mothers who come as their children’s illness and information provision has not been improving the knowledge of mothers on child pneumonia prevention. This study aims to compare the effectiveness of booklets provision and buzz group methods to increase knowledge, attitudes and practices of mothers in the prevention of pneumonia in children.Method: This study employed a quasi experimental design with non-equivalent control group. The sample of this study is the mothers who have children 0-5 years old, in Nangalimang and Kabor villages and 90 mothers were selected by using systematic random sampling technique. Data was collected using face to face interview by trained enumerators guiding with close-ended questionnaire that has been validated. Data were then analyzed by Chi-Square test and Manova Post Hoc Tukey.Results: Pneumonia lectures followed by giving booklets and buzz group discussion were effective in increasing maternal knowledge and attitudes in the prevention of children pneumonia. Whereas, buzz group were more effective in improving the practice of mothers in the prevention of pneumonia than the provision of booklets. This is because the buzz method makes mothers more actively participate and creative in solving pneumonia problems by looking at other mothers' experiences. It is recommended that using buzz group lectures as an alternative method in efforts to health education for mothers, especially in the prevention of children pneumonia.
Transfer of Nickel from Polluted Soil to Pisum sativum L. and Raphanus sativus L. under Composted Green Amendment and Native Soil Microbes
Authors: Nafady Nivien Allam , Mazen Mohamed Bahy-El-Din , Ahmed Mohamed Mahmoud Mohamed , Monsef Omaima Abdel 
Published: November 2018

Abstract
The effect of compost, inoculation with native soil microbes and their residual effects on bioavailability of nickel by peas (Pisum sativum L.) and radish (Raphanus sativus L.) grown on polluted soil were investigated in pot experiments. Plants were amendment with different compost levels (0, 0.2, 0.4, 0.6% of soil dry weight) and inoculated with different native soil microbes (4 fungal species, one bacterial species, 4 species of arbuscular mycorrhizal fungi) isolated from the polluted soil under study. Significant increases in the biomass of pea and radish plants were observed as a result of amendment application and their residual effects. The mycorrhizal dependency (MD) of pea plants was lower than of radish plants. The highest reductions of Ni levels in both plants were observed by the simultaneous applications of compost with microbes or mycorrhizal fungi to polluted soils. Soil pH increased significantly (p < 0.05) as a result of applying native microbes especially with arbuscular mycorrhizal fungi (AMF) alone or combined with compost. The DTPA extractability of soil Ni was significantly decreased with increasing soil pH (p < 0.05). The minimum transfer factor of Ni from polluted soil were 0.067 and 0.089 for pea and radish plants, respectively which were attained as a result of applying compost (0.6% of soil weight) inoculated with mycorrhizal fungi. From the results, we can conclude that the use of compost and native soil microbes as a soil remediate could be an effective strategy for soil remediation.
The (In)Voluntary in the Timaeus and the Eudemian Ethics
Authors: Wolt Daniel 
Published: November 2018

Abstract
Plato’s Timaeus contains an argument that vice is involuntary. Here I present an interpretation of that argument and, upon doing so, relate the underlying conception of voluntariness to that found in Aristotle’s Eudemian Ethics. I argue that in the Timaeus, for something to be voluntary it must be caused by the agent’s intellect (nous) in a certain way. This idea, in turn, relies on an identification of the agent with her intellect: the reason that what is voluntary must be caused by the agent’s intellect is that what is voluntary is what the agent herself is responsible for. The conception of the voluntary in the Eudemian Ethics differs less radically than one might think. There too Aristotle wishes to respect the idea that there is an important connection between what is voluntary and what is caused by our rational capacities, but he differs in how he fills out the relevant rational capacities.
Parameterization of Seersucker Woven Fabrics Using Laser Techniques
Authors: Frącczak Łukasz , Rafał Domagała , Piotr Zgórniak , Matusiak Małgorzata 
Published: November 2018

Abstract
Seersucker woven fabrics are increasingly used in the textile industry. Unfortunately, their popularity is limited due to the lack of standards and parameterization of their structure. Thus, the designer of the finished product (clothing, bedding, or decorative items) has problems with ordering a fabric with a specific structure and properties. In this context, it is necessary to parameterize them. This paper presents a method for measuring the surface geometry of seersucker woven fabrics using laser techniques. The surface geometry of the seersucker woven fabric was determined using adapted roughness parameters, such as Wz, Ra, and Rz, as well as by using a hypsometric map.
Criminal Evidence: Evidencing Defences to Murder. R v Goodwin (Anthony Gerard) [2018] EWCA Crim 2287
Authors: Singh Dr. Charanjit 
Published: November 2018

Abstract
The defendant (Goodwin) (G) had bludgeoned the victim to death with a hammer. At trial he pleaded self-defence and in the alternative loss of control, the latter being a partial defence to murder.Section 54(1) of the Coroners and Justice Act 2009. The Court of Appeal held that the trial judge was right not to leave the partial defence to murder to the jury given the facts. The Court made observations in relation to how a trial judge should approach the partial defence including the fact that relevant and admissible evidence would be required for each of its elements.