bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presence of autoimmune disease affects not only risk but also survival in patients with B‐cell non‐Hodgkin lymphoma
Authors: Kleinstern Geffen , Averbuch Mor , Abu Seir Rania , Perlman Riki , Ben Yehuda Dina , Paltiel Ora 
Published: February 2018

AbstractAlthough autoimmune diseases (AIDs) are known to predispose to non‐Hodgkin lymphoma (NHL), their association with NHL prognosis has rarely been investigated. We examined associations between autoimmunity and B‐cell NHL onset by comparing AID history (determined by self‐report and medication review and supplemented by chart review where possible) among 435 adult B‐NHL patients in Hadassah‐Hebrew University Medical Center, diagnosed 2009‐2014, and 414 age‐and‐sex frequency‐matched controls. We examined AIDs as a whole, B‐ and T‐cell–mediated AIDs, and autoimmune thyroid diseases. Among cases, we used Kaplan‐Meier and Cox regression models to assess the association of AID with overall survival and relapse‐free survival, adjusting for prognostically important patient and disease characteristics such as Ki67% staining, International Prognostic Index, rituximab treatment, and histological subgroup.Autoimmune diseases were associated with B‐NHL (odds ratio [OR] = 1.95; 95% confidence interval (CI), 1.31‐2.92), especially AIDs mediated by B‐cell activation (OR = 5.20; CI, 1.90‐14.3), which were particularly associated with marginal zone lymphoma (OR = 19.3; CI, 4.59‐80.9). We found that time to relapse for all B‐NHL patients with AIDs was significantly shorter (mean of 49.21 mo [±3.22]) than among patients without AID (mean of 59.74 mo [±1.62]), adjusted hazard ratio [HRadj] = 1.69 (CI, 1.03‐2.79). Specifically, in patients with diffuse large B‐cell lymphoma, of whom 91.8% had received rituximab, a history of B‐cell–mediated AIDs was associated with shorter relapse‐free survival and overall survival, HRadj = 8.34 (CI, 3.01‐23.1) and HRadj = 3.83 (CI, 1.20‐12.3), respectively.Beyond confirming the well‐known association between AIDs and B‐NHL, we found that AID is an adverse prognostic factor in B‐cell lymphoma, associated with a shortened time to relapse, suggesting that there are specific therapeutic challenges in the subgroup of patients suffering from both these diseases. Further work is required to address mechanisms of resistance to standard treatment in the setting of AID‐associated B‐NHL. In the era of immunotherapy, these findings have particular relevance.
Examining morning HPA axis activity as a moderator of hostile, over‐reactive parenting on children's skills for success in school
Authors: Lipscomb Shannon T. , Becker Derek R. , Laurent Heidemarie , Neiderhiser Jenae M. , Shaw Daniel S. , Natsuaki Misaki N. , Reiss David , Fisher Philip A. , Leve Leslie D. 
Published: February 2018

AbstractThis study examined children's morning hypothalamic–pituitary–adrenal (HPA) axis activation as a moderator of links between hostile, over‐reactive parenting at age 4.5 years and children's skills for success in school (higher executive function and literacy and less externalizing behaviour) at age 6. Participants included 361 adoptive families. Parenting was self‐reported. HPA axis activation was measured by basal levels in morning cortisol. Executive function and literacy were assessed via standardized tasks. Externalizing behaviour was reported by teachers. Results indicated that hostile, over‐reactive parenting predicted more externalizing behaviour and lower executive functioning regardless of children's morning HPA axis activation. HPA axis activation moderated the effects of hostile, over‐reactive parenting on literacy. Among children with moderate to high morning HPA axis activation (approximately 60% of the sample), harsh parenting was linked with lower literacy; children with low morning HPA axis activation exhibited better literacy in the context of more hostile, over‐reactive parenting. Yet, across the sample, hostile, over‐reactive parenting remained in the low to moderate range, not in the high range. Findings are discussed in the context of considering not only whether children's stress system activation moderates responses to their environments but also how these processes operate for different developmental outcomes.Highlights

This study examined children's morning HPA axis activation as a moderator of links between parenting at age 4.5 and children's skills for success in school at age 6.
Participants included 361 adoptive families, measured with cortisol, parenting, executive function, literacy, and externalizing behavior.
Children's morning cortisol levels moderated the associations between hostile, over‐reactive parenting, and emergent literacy but not externalizing behavior or executive function.
How Do Teachers Develop and Enact a Disciplinary View of Literacy in Mathematics
Authors: Temple Codruta , Doerr Helen M. 
Published: February 2018

AbstractThis commentary describes some disciplinary literacy practices observed in mathematics classrooms, discusses factors that might influence teachers’ decisions to integrate literacy with content instruction, and proposes that collaboration with disciplinary experts, in addition to literacy experts, may help reorient teachers’ practice toward a disciplinary take on the literacy demands of their subject area.
Meaningful and Expansive: Literacy Learning Through Technology‐Mediated Productions
Authors: Crampton Anne E. , Scharber Cassandra , Lewis Cynthia J. , Majors Yolanda J. 
Published: February 2018

AbstractMost people have struggled with reading in one situation or another, depending on their appreciation for the content, their prior experiences, and the texts. This department column shares ways for educators to help literacy learners unlock their potential with instruction anchored in their skills, knowledge, ways of learning, interests, and attitudes.
Alteration of renal excretion pathways in gentamicin‐induced renal injury in rats
Authors: Ma Yan‐rong , Luo Xuan , Wu Yan‐fang , Zhang Tiffany , Zhang Fan , Zhang Guo‐qiang , Wu Xin‐an 
Published: February 2018

AbstractThe kidney plays a major part in the elimination of many drugs and their metabolites, and drug‐induced kidney injury commonly alters either glomerular filtration or tubular transport, or both. However, the renal excretion pathway of drugs has not been fully elucidated at different stages of renal injury. This study aimed to evaluate the alteration of renal excretion pathways in gentamicin (GEN)‐induced renal injury in rats. Results showed that serum cystatin C, creatinine and urea nitrogen levels were greatly increased by the exposure of GEN (100 mg kg–1), and creatinine concentration was increased by 39.7% by GEN (50 mg kg–1). GEN dose‐dependently upregulated the protein expression of rOCT1, downregulated rOCT2 and rOAT1, but not affected rOAT2. Efflux transporters, rMRP2, rMRP4 and rBCRP expressions were significantly increased by GEN(100), and the rMATE1 level was markedly increased by GEN(50) but decreased by GEN(100). GEN(50) did not alter the urinary excretion of inulin, but increased metformin and furosemide excretion. However, GEN(100) resulted in a significant decrease of the urinary excretion of inulin, metformin and p‐aminohippurate. In addition, urinary metformin excretions in vivo were significantly decreased by GEN(100), but slightly increased by GEN(50). These results suggested that GEN(50) resulted in the induction of rOCTs‐rMATE1 and rOAT3‐rMRPs pathway, but not changed the glomerular filtration rate, and GEN(100)‐induced acute kidney injury caused the downregulated function of glomerular filtration ‐rOCTs‐rMATE1 and ‐rOAT1‐rMRPs pathway.
Evaluation of chalcones as inhibitors of glutathione S‐transferase
Authors: Özaslan Muhammet Serhat , Demir Yeliz , Aslan Hatice Esra , Beydemir Şükrü , Küfrevioğlu Ömer İrfan 
Published: February 2018

AbstractGlutathione S‐transferases (GSTs) are the superfamily of multifunctional detoxification isoenzymes and play an important role in cellular signaling. In the present study, potential inhibition effects of chalcones were tested against human GST. For this purpose, GST was purified from human erythrocytes with 5.381 EU⋅mg−1 specific activity and 51.95% yield using a GSH–agarose affinity chromatographic method. The effects of chalcones on in vitro GST activity were tested at various concentrations. Ki constants of chalcones were found in the range of 7.76–41.93 μM. According to the results, 4‐fluorochalcone showed a better inhibitory effect compared with the other compounds. The inhibition mechanisms of 2'‐hydroxy‐4‐methoxychalcone and 4‐methoxychalcone were noncompetitive, whereas the inhibition mechanisms of 4'‐ hydroxychalcone, 4‐ fluorochalcone, and 4,4'‐ diflurochalcone were competitive.
The Extent and Determinants of Tax Gap in the Informal Sector: Evidence from Ghana
Authors: Danquah Michael , Osei‐Assibey Eric 
Published: February 2018

AbstractIn this paper, we attempt to estimate the tax gap in the informal sector as well as the contributing factors of the tax losses in SSA countries using Ghana as a case study. Using micro data on non‐farm household enterprises obtained from the sixth round of the Ghana Living Standards Survey as well as data on quarterly tax payable by specified small scale enterprises derived from the Small Tax Payer office of the Ghana Revenue Authority, the findings show that the national potential and actual taxes in the informal sector are US$ 81 974 846 and US$ 25 023 273, respectively, reflecting an estimated national tax gap or loss of approximately US$ 56 951 573. Firm level variables such as type of business, urban location and experience of the firm significantly increase the propensity to pay tax and reduce the tax gap. Copyright © 2018 John Wiley & Sons, Ltd.
Tarsal attachment devices of the southern green stink bug Nezara viridula (Heteroptera: Pentatomidae)
Authors: Rebora Manuela , Michels Jan , Salerno Gianandrea , Heepe Lars , Gorb Elena , Gorb Stanislav 
Published: February 2018

AbstractBased on analyses with cryo‐scanning and transmission electron microscopy, the present study reports on the morphology and ultrastructure of the attachment structures of the green stinkbug Nezara viridula L. (Heteroptera: Pentatomidae), a cosmopolitan pest of different crops in most areas of the world. In addition, the presence and distribution of large proportions of the elastic protein resilin in these structures was revealed by confocal laser scanning microscopy. The attachment structures of each leg comprise two sclerotised claws, a pair of smooth flexible pulvilli and a hairy adhesive pad located at the ventral side of the basitarsus. No sexual dimorphism is evident. Contact areas of resting individuals on a smooth surface show that N. viridula creates contact to the substrate with the ventral surface of (a) the distal portions of the pulvilli, (b) the setae of the hairy adhesive pad, (c) the two paraempodia representing mechanosensory setae, and (d) the tips of the claws. Each pulvillus is a sac‐like structure formed by complex cuticular layers that vary in their structure and resilin content. The dorsal side consists of sclerotised chitinous material, while the ventral cuticle consists mainly of resilin and shows a very thin epicuticle and a thick exocuticle. The setae of the hairy adhesive pad are pointed and socketed. They exhibit a pronounced longitudinal gradient in the material composition, with large proportions of resilin being present in the setal tips. In most of these setae, especially in those of the distal‐most part of the pad, also a transverse gradient in the material composition is visible.
Low‐dose T1W DCE‐MRI for early time points perfusion measurement in patients with intracranial tumors: A pilot study applying the microsphere model to measure absolute cerebral blood flow
Authors: Li Ka‐Loh , Lewis Daniel , Jackson Alan , Zhao Sha , Zhu Xiaoping 
Published: February 2018

BACKGROUNDPrevious studies have measured cerebral blood flow (CBF) with DSC‐MRI using an “early time points” (ET) method based on microsphere theory.PURPOSETo develop and assess a new ET method for absolute CBF estimation using low‐dose high‐temporal (LDHT) T1W‐DCE‐MRI.STUDY TYPERetrospective cohort study.SUBJECTSSeven patients with sporadic vestibular schwannoma (VS) who underwent test–retest imaging; one patient with glioblastoma multiforme (GBM) imaged pretreatment; and 12 neurofibromatosis type 2 (NF2) patients undergoing bevacizumab treatment, imaged pre‐ and 90 days posttreatment.FIELD STRENGTH/SEQUENCELDHT‐DCE‐MRI was performed at 1.5 and 3.0T, using 3D spoiled gradient echo with phase cycling. DSC‐MRI performed in one patient, using 3D echo‐shifted multi‐shot echo‐planar imaging (PRESTO) at 3T.ASSESSMENTThrough Monte Carlo simulations, CBF estimation using three newly developed average contrast agent concentration (AC) ‐based methods (ACrPK, ACrMG, ACcomb), was compared against conventional maximum gradient (MG) approaches, at varying Rician noise levels. Reproducibility and applicability of the ACcomb method was assessed in our sporadic‐VS/GBM/NF2 patient cohort, respectively.STATISTICAL TESTSReproducibility was measured using test–retest coefficient of variation (CoV). Pre‐ and posttreatment CBF values were compared using paired t‐test with Bonferroni correction.RESULTSMonte Carlo stimulations demonstrated that AC‐based methods, particularly ACcomb, offered superior accuracy to conventional MG approaches. Overall test–retest CoV using the ACcomb method was 5.76 in normal‐appearing white matter (NAWM). The new ACcomb method produced gray matter/white matter CBF estimates in the NF2 patient cohort of 55.9 ± 13.9/25.8 ± 3.5 on day 0; compared with 155.6 ± 17.2/128.4 ± 29.1 for the classical MG method. There was a moderate (10% using ACcomb and ACrPK) increase in CBF of NAWM 90 days post therapy (P = 0.03 and 0.005).DATA CONCLUSIONOur new AC‐based method of CBF estimation offers excellent reproducibility, and displays more accuracy in both Monte Carlo analysis and clinical data application, than conventional MG‐based approaches.Level of Evidence: 1Technical Efficacy: Stage 4J. MAGN. RESON. IMAGING 2018;48:543–557.
From being diverse to becoming diverse: A dynamic team diversity theory
Authors: Li Jia , Meyer Bertolt , Shemla Meir , Wegge Jürgen 
Published: February 2018

SummaryOn the basis of the literature of open systems and team diversity, we present a new dynamic team diversity theory that explains the effect of change in team diversity on team functioning and performance in the context of dynamic team composition. Building upon the conceptualization of teams as open systems, we describe the enlargement and decline of team variety, separation, and disparity through member addition, subtraction, and substitution. Then, focusing on diversity enlargement, we theorize the contemporaneous and lasting effects of team diversity change on team performance change and on team processes and states leading to them. Dynamic team diversity theory expands the focus of team diversity research from teams' being more diverse than others to teams' becoming more diverse than before. It aims to advance team diversity research to be better aligned with the organizational reality of dynamic team composition. We also discuss methodological considerations in subsequent empirical testing of the theory and highlight how the theory and future research may help to guide organizational practice in recomposing work teams.
Association of marijuana use with oral HPV infection and periodontitis among Hispanic adults: Implications for oral cancer prevention
Authors: Ortiz Ana P. , González Daisy , Ramos Jeslie , Muñoz Cristina , Reyes Juan Carlos , Pérez Cynthia M. 
Published: February 2018

AbstractBackgroundDespite limited data, research suggests that marijuana use is associated with oral HPV infection and periodontitis, two potential oropharyngeal cancer risk factors. We assessed these associations in a Hispanic adult population in Puerto Rico.MethodsA cross‐sectional study of 735 adults assessed marijuana use, determined through an audio computer‐assisted self‐interview, and periodontitis and self‐collection of oral HPV samples following the National Health and Nutrition Examination Survey methodology. The Centers of Disease Control and Prevention/American Academy of Periodontology definition was used for periodontitis. HPV typing was performed using polymerase chain reaction with modified L1 consensus primers (MY09/MY11).Results26.5% of adults reported lifetime use of marijuana, 2.7% were frequent users (lifetime use ≥ 26 times, past year use ≥ 6 times, and past 30‐day use ≥2 times), 5.7% had oral HPV infection, and 20.1% had severe periodontitis. The multivariate logistic regression analysis showed that frequent marijuana users were more likely to have severe periodontitis (OR = (2.93, 95%: 1.08–7.96)) than never/once lifetime users after adjusting for age, sex, healthcare coverage, smoking, binge drinking, number of oral sex partners, and oral HPV infection. However, frequent marijuana use was not associated with oral HPV infection.ConclusionMarijuana use was associated with periodontitis, but not with oral HPV infection. Further evaluation of the role of marijuana use in oral HPV infection and periodontitis may inform novel preventive public health strategies, as marijuana users could be at increased risk of oral cancer.
Reconstruction using a constrained‐type hip tumor prosthesis after resection of malignant periacetabular tumors: A study by the Japanese Musculoskeletal Oncology Group (JMOG)
Authors: Ogura Koichi , Susa Michiro , Morioka Hideo , Matsumine Akihiko , Ishii Takeshi , Hamada Kenichiro , Ueda Takafumi , Kawai Akira 
Published: February 2018

BackgroundWe conducted a nationwide survey of prosthetic reconstruction using a constrained‐type hip tumor prosthesis (C‐THA) following resection of periacetabular tumors.MethodsEighty patients with periacetabular tumors underwent wide resection and prosthetic reconstruction using C‐THA at JMOG‐affiliated institutions (39 males and 41 females; mean age, 46.7 years; mean follow‐up period, 65 months). Primary bone or soft tissue sarcoma accounted for 75% of the cases. Adjuvant radiotherapy and chemotherapy were performed for 12 and 37 patients, respectively.ResultsThere were 21 local recurrences (26%), necessitating amputation in 2 patients. Other postoperative complications included deep infection in 31 patients (39%), delayed wound healing in 25 (31%), and prosthesis‐related complications requiring surgery in 7 (9%). Removal of the prosthesis was required in 23 patients (29%) (deep infection (n = 20), local recurrence resulting in amputation (n = 2), and outer cup displacement (n = 1). Patients whose abductor muscle was conserved or who underwent functional abductor muscle reconstruction showed significantly longer prosthesis survival. No postoperative wound complications occurred in three recent patients undergoing wound management with a RAM flap. The mean MSTS score was 43%.ConclusionsWe analyzed the outcome of 80 patients with periacetabular tumors undergoing C‐THA reconstruction. The rates of postoperative complication were still high, but comparable to those in previous studies. Our results suggest wound management using a RAM flap is useful for reducing wound complications.
Indexing the Internet
Authors: McFadden T. G. 
Published: February 2018

ABSTRACTDescribes some of the historical problems and technological advances that make electronic publishing so attractive as an alternative to print. But while the future may be now, it is not without complication. Indexes and the texts to which they point have traditionally been print products; many of the same problems plague both as electronic products. While many of the issues are still unclear, and many of the solutions only tentative, the pattern is unavoidable: electronic publishing is a growth industry and an expanding market; indexers need to adapt their practices to survive.
The East and Central Europe Journal Donation Project
Authors: Mack Arien 
Published: February 2018

ABSTRACTThe East and Central Europe Journal Donation Project was begun in 1991 in response to the great need of academic, research and national libraries in all the former Soviet dominated countries. It aims to create current journal archives for as many libraries in the region as possible through donated subscriptions by publishers. In the past year over 21,000 journals were given to approximately 200 recipient libraries. The project welcomes new participants.
The ballasting effect of Saharan dust deposition on aggregate dynamics and carbon export: Aggregation, settling, and scavenging potential of marine snow
Authors: van der Jagt Helga , Friese Carmen , Stuut Jan‐Berend W. , Fischer Gerhard , Iversen Morten H. 
Published: February 2018

AbstractLithogenic material such as Saharan dust can be incorporated into organic aggregates and act as ballast, potentially enhancing the marine carbon export via increased sinking velocities of aggregates. We studied the ballasting effects of Saharan dust on the aggregate dynamics in the upwelling region off Cape Blanc (Mauritania). Aggregate formation from a natural plankton community exposed to Saharan dust deposition resulted in higher abundance of aggregates with higher sinking velocities compared to aggregate formation with low dust. This higher aggregate abundance and sinking velocities potentially increased the carbon export 10‐fold when the aggregates were ballasted by Saharan dust. After aggregate formation in the surface waters, subsequent sinking through suspended Saharan dust minerals had no influence on aggregate sizes, abundance, and sinking velocities. We found that aggregates formed in the surface ocean off Mauritania were already heavily ballasted with lithogenic material and could therefore not scavenge any additional minerals during their descent. This suggests that carbon export to the deep ocean in regions with high dust deposition is strongly controlled by dust input to the surface ocean while suspended dust particles in deeper water layers do not significantly interact with sinking aggregates.
Beyond respiration: Controls on lateral carbon fluxes across the terrestrial‐aquatic interface
Authors: Tank Suzanne E. , Fellman Jason B. , Hood Eran , Kritzberg Emma S. 
Published: February 2018

AbstractUnderstanding what controls the lateral flux of organic and inorganic carbon from landscapes to surface waters is key to fully understanding terrestrial ecosystem carbon balances, the biogeochemistry of freshwaters, and how the hydrologically‐mediated movement of carbon between these ecosystems may be altered by global change. In this paper, we synthesize current knowledge and identify major knowledge gaps in our understanding of land‐to‐water fluxes of dissolved and particulate organic carbon, CO2, and bicarbonate by exploring: (1) how variations in soil carbon stocks affect dissolved and gaseous carbon production in the soil profile and transport via terrestrial‐aquatic flow paths, and (2) the effect of global change on these lateral carbon fluxes. Our aim is to develop a roadmap to guide future research on terrestrial‐aquatic linkages in the carbon cycle within the context of changes in climate, global biogeochemical cycles, and land use.