bluuebunny/crossref_metadata_2025_split huggingface dataset:
Figure 5 from PINK1-Mediated Mitochondrial Activity Confers Olaparib Resistance in Prostate Cancer Cells
Authors: Schaaf Zachary A. , Ning Shu , Leslie Amy R. , Sharifi Masuda , Gao Richard Y. , Maine James P. , Lou Wei , Lombard Alan P. , Liu Chengfei , Yu Ai-Ming , Mitsiades Nicholas , Gao Allen C. 
Published: November 2024

<p>Seahorse Mito Stress Test assay results comparing 2B-OlapR cells with and without siPINK treatment at basal state and with mitochondrially relevant pharmacologic supplementation to deduce relative function convey decreased function after PINK1 expression ablation. <b>A</b> and <b>B,</b> Mito Stress Test summary graphic representing differential OCR and extracellular acidification rate between nonspecific and siPINK1-targeted OlapR cells. <b>C,</b> Cellular OCR at basal state is greatly reduced with PINK1 excision. <b>D,</b> ATP production–associated oxygen consumption is markedly reduced in 2B-OlapR cells treated with siPINK1. <b>E</b> and <b>F,</b> PINK1 expression reduction reveals consequential decreased spare capacity for respiration, as well as lessened maximal rate of ETC-based oxygen consumption. <b>G,</b> Decreasing PINK1 levels leads to less proton leakage out of the inter-mitochondrial membrane space inferred by OCR reading differences after oligomycin addition and after rotenone and antimycin addition. ECAR, extracellular acidification rate. <math><mo>*</mo><mo>*</mo><mo>,</mo><mo> </mo><mi>P</mi><mo>≤</mo><mn>0</mn><mo>.</mo><mn>01</mn><mo>;</mo><mo> </mo><mo>*</mo><mo>*</mo><mo>*</mo><mo>,</mo><mo> </mo><mi>P</mi><mo>≤</mo><mn>0</mn><mo>.</mo><mn>001</mn></math>.</p>
Re-Imagining Transformative Strategies to End Minority Marginalization in Ethiopia
Authors: Mohammed Awol Ali 
Published: November 2024

Abstract
Since 1991, Ethiopia embarked on a journey to create an ethnically egalitarian state, aiming to rectify historical injustices and protect minority rights. Ironically, what was meant to be a beacon of equality has turned into a pervasive experience of minority marginalization. This stark reality underscores the failures of the existing legal and institutional frameworks. This article, therefore, critically examine the transformative strategies to end marginalization of minorities in Ethiopia. The study employed a qualitative research approach blending both primary and secondary data sources. The findings revealed that the failures of existing constitutional promises and institutional frameworks regarding the protection of minority rights, necessitating re-imaginations of transformative strategies. The study advocates for the progression of national and local minority rights institutions, the implementation of transitional justice measures, the instigation of electoral reforms, and the decentralization of power. Furthermore, the establishment of minority autonomous governance and the augmentation of local government capacity are recommended. Additionally, the formation of national minority councils, accentuating parliamentary endorsement for legislative reforms by minority representatives and public service reform is suggested to enhance minority employment opportunities. Lastly, the study recommended equal media access to promote the political participation and freedom of expression of marginalized minority groups.
Hannah Arendt and Michel Foucault on History, Tradition, and Modernity
Authors: Neill Edmund 
Published: November 2024

Abstract
This article interrogates the different ways in which Arendt and Foucault seek to conceptualize tradition in their work. First, it analyses Arendt’s approach, arguing that she put forward three overlapping accounts of the Western tradition – one that criticized the alienating effects of post-seventeenth-century science, one that criticized the Western philosophical tradition as a whole for favouring ‘making’ and ‘contemplation’ over ‘action’, and one that sought to explain the advent of totalitarianism through the stresses that imperialism and racism put upon Western political thought. These approaches are then contrasted with Foucault’s. It is argued that he differed significantly in not believing that there was one Western tradition, laid less stress on totalitarianism, was more of a historicist, and distinguished less between the ‘political’ and the ‘social’. Nevertheless there were important overlaps between Arendt and Foucault’s approaches. Both were critical of the instrumentalizing and technocratic effects of modern science, both stressed the importance of unpredictable events in history, and both believed that examining the Western tradition critically offered important alternatives for modern politics – though neither thought that these would lead to any simple gaining of liberal ‘autonomy’.
The Politics of Method: Arendt and Foucault on Hobbes
Authors: Herrera Helphand Dawn 
Published: November 2024

Abstract
In The Origins of Totalitarianism (1951) and the “Society Must Be Defended” lectures (1975–1976), Hannah Arendt and Michel Foucault present unexpected engagements with Thomas Hobbes’ Leviathan. This article contextualizes and elucidates their interpretations of Hobbes by foregrounding the genealogical aspect of their projects. Their readings of Leviathan reflect common methodological commitments and figure the distinct but related problematics which Foucault and Arendt articulate, encapsulating the differences between their influential conceptions of power. The article concludes with a reading of Hobbes’ theory of the liberty of subjects, which, while not explicitly addressed by Arendt or Foucault, lends support to their treatments of his text. Comparing their readings of Hobbes opens a potentially generative dialogue between their critiques of sovereignty and racialized state violence.
Labor as an Overlooked Entry Point into the Modern Age in the Works of Arendt and Foucault
Authors: Imbrasaite Jurgita 
Published: November 2024

Abstract
This paper explores Arendt’s and Foucault’s thinking through the lens of the modern labor paradigm. Even if the question of labor is a less prominent path in both thinkers’ research, it leads to the heart of the modern era as they both understand it. In their respective fields, Arendt and Foucault sketch a similar link between the beginning of the modern age and the transformation of the notion of labor. While Arendt directly examines the modern glorification of labor and the emergence of the labor society, Foucault provides numerous analyses of labor as an instrument and target of disciplinary society, along with an epistemic distinction of modernity deeply connected to the term, ‘labor.’ This joint reading contributes to what might be called their philosophies of labor, as well as to the ongoing debate about the nature and meaning of labor in contemporary society.
The Implementation of Active, Bodily Experience Mathematics Learning Activities: the Perspective of Italian Primary and Secondary School Mathematics Teachers
Authors: Boscolo Alessandra 
Published: November 2024

Abstract
Despite the growing emphasis on embodied education in mathematics research, it remains unclear how extensively these ideas permeate schools. Through an exploratory survey, we pinpoint common traits and differences in beliefs among a convenience sample of Italian primary and secondary school mathematics teachers, searching for contextual and individual factors that could influence the active, bodily experience mathematics learning (ABM) activities implementation. Teachers refer to the insufficient availability of suitable spaces and resources as the primary obstacle to implementation, while lack of familiarity and guidance is another significant challenge. Secondary school teachers, and in particular those who reported to integrate fewer such activities in the classroom, express concerns about time constraints, leading to diminished belief in the efficacy of ABM activities. Transfer of learning is reported by teachers as the greatest difficulty for students. Providing specific training, along with concrete examples of resources, is hypothesized to be a key supportive strategy.
The impact sheet to this article can be accessed at 10.6084/m9.figshare.27151194.
For an … «Artificially Intelligent» Process
Authors: Capasso Valentina 
Published: November 2024

Abstract
It is generally understood that covid-19 pandemics, in exacerbating already existent inefficiencies of the judicial systems, at the same time offered an opportunity to cope with them. Indeed, problems such as courts backlog intensified by the delay accumulated during the pandemic; the digital divide, made more pressing by the need to initiate and conduct proceedings electronically, itself a source of doubts as to the current need for physical hearings and, consequently, the for proximity of the Courts, were already known to the States. Similarly, for some years now, there has been a widespread awareness that, in order to achieve a better rationalization of resources, procedural reforms are not sufficient. That is why the contribution does not discuss the latest Italian procedural reform in detail, nor its criticalities. Rather, it focuses on an apparently minor provision, which looks instead capable of explaining effects that go well beyond those imagined by the Legislator and whose interest may transcend national borders, namely article 46 of the Code of civil procedure Implementing Rules. As the Author tries to demonstrate, this proviso, if fully exploited, could combine with weak artificial intelligence (ai) tools and with already known caseload management techniques to ensure greater rationalization of judicial resources and easier access to justice.
The Impacts of Predictive Justice in Civil Litigation
Authors: Martins João Marques 
Published: November 2024

Abstract
Predictive justice is the informal name for a computer tool equipped with artificial intelligence capable of predicting the outcome of a court case, based on previous decisions on similar cases. As a valuable source of information for lawyers and judges, its usefulness seems unquestionable. But the problems it raises are no less obvious. From the outset, the accuracy of the output can be questioned. The psychological impact of the predictions on the judge, conditioning her decision-making autonomy, is also worrisome. In addition, there are concerning uncertainties about the negative effect of these tools on the training of trainee lawyers, since one of their most frequent and formative tasks will be carried out by machines. Finally, and assuming that these tools can profile the professional skills of judges and lawyers, we should ask whether this is desirable or even acceptable.
Civil Procedure and the Rule of Law in Scandinavia
Authors: Nylund Anna 
Published: November 2024

Abstract
Although courts are essential institutions in the rule of law, the nexus between the rule of law and civil procedure law is seldom discussed in depth. Courts not only resolve disputes, but they are also a vehicle for the vindication of legal rights, promoting the clarity and coherence of the law, and governance through the law. This article analyses how the historical and prevailing legal ideologies in Scandinavian societies shape how the values of the rule of law are materialised through court proceedings. It argues that the perceived primary role of Scandinavian law oscillates between stressing the private and public functions of courts, and with views on legal rights. The analysis is divided into three periods: the zenith of Scandinavian realism and the welfare state, the influx of access to justice movement and European law, and the current age in which New Public Management has put its mark.
Dignity of women with systemic lupus erythematosus: A qualitative study
Authors: Mohebbi Zinat , Bagherian Samaneh , Eckert Marion , Tehranineshat Banafsheh 
Published: November 2024

Background: The nature of systemic lupus erythematosus (SLE) and the far-reaching unpleasant consequences of this disease and the treatments can put the dignity of the women with the disease at risk. Yet, the dignity of this population of patients has not been the subject of much research. Objective: The present study aims to define and describe the concept of dignity of women with SLE. Research design: This is a qualitative descriptive study in which data were collected via individual, in-depth, semi-structured interviews. The collected data were analyzed using methods of content analysis in MAXQDA 2010. Participants and research context: In total, 29 individuals (14 patients, 8 family caregivers, and 7 nurses) were selected by purposeful sampling from the internal wards of a teaching hospital located in the south of Iran. The study was conducted between June 2023 and February 2024. Sampling continued until the data were saturated. Ethical considerations: The Institutional Review Board of the university has verified that the study complies with research ethics. Findings: Analysis of the data extracted from the interviews resulted in three themes: respect for identity, compassion in care and treatment, and fulfillment of support needs. Conclusions: The women with SLE who were surveyed in the present study needed to have their feminine identity and social identity respected and be comprehensively supported by their treatment team and family caregivers. In such a context, care characterized by compassion and empathy and treatment teams’ respectful and professional interactions with the patients contribute to maintaining the patients’ dignity. Nursing managers and staff can use the findings of the present study to create a supportive clinical environment in order to better maintain the dignity of women with SLE.
Facing Illness Together: Understanding the Role of the Couple in Palliative Care
Authors: Chammas Danielle , Fishel Anne , Cramer Margaret , Brenner Keri O. , Rosenberg Leah B. 
Published: November 2024

Serious illness is rarely experienced by patients in isolation. Many patients present to palliative care (PC) accompanied by their intimate partner. The intimate partnership is a critical axis around which many patients' experiences of serious illness revolve. However, there is a lack of literature and training on how PC clinicians can effectively support couples as a unit. Many existing PC communication strategies can be expanded to the dyadic unit, offering more holistic support for patients, partners, and the entity of their relationship. This paper integrates concepts from couples therapy, psychology, and PC communication to provide insights into the emotional, psychological, interpersonal, and practical challenges couples face during serious illness, as well as opportunities for growth and resilience. Key strategies for PC clinicians include helping couples navigate shifts in relational identity, share the “emotional housework,” and transform conflict into connection. Concrete techniques are illustrated throughout this manuscript, employing clinical micro-vignettes to demonstrate their practical application in PC practice. Recognizing the couple as a unified entity empowers clinicians to foster open communication, helping couples maintain connection and evolve intimacy throughout the illness journey. By applying relational concepts and acknowledging the couple’s shared experience, PC clinicians can enhance the quality of life for both patients and their partners. Conceptualizing the couple as a distinct entity within PC practice can deepen clinician-patient communication and improve therapeutic effectiveness.
Identification of Distinct Visual Scan Paths for Pathologists in Rare-Element Search Tasks
Authors: Lopes Alana , Rasmussen Sean , Au Ryan , Chakravarthy Vignesh , Chinnery Tricia , Christie Jaryd , Djordjevic Bojana , Gomez Jose A. , Grindrod Natalie , Policelli Robert , Sharma Anurag , Tran Christopher , Walsh Joanna C. , Wehrli Bret , Ward Aaron D. , Cecchini Matthew J. 
Published: November 2024

Background The search for rare elements, like mitotic figures, is crucial in pathology. Combining digital pathology with eye-tracking technology allows for the detailed study of how pathologists complete these important tasks. Objectives To determine if pathologists have distinct search characteristics in domain- and nondomain-specific tasks. Design Six pathologists and six graduate students were recruited as observers. Each observer was given five digital “Where's Waldo?” puzzles and asked to search for the Waldo character as a nondomain-specific task. Each pathologist was then given five images of a breast digital pathology slide to search for a single mitotic figure as a domain-specific task. The observers’ eye gaze data were collected. Results Pathologists’ median fixation duration was 244 ms, compared to 300 ms for nonpathologists searching for Waldo ( P < .001), and compared to 233 ms for pathologists searching for mitotic figures ( P = .003). Pathologists’ median fixation and saccade rates were 3.17/second and 2.77/second, respectively, compared to 2.61/second and 2.47/second for nonpathologists searching for Waldo ( P < .001), and compared to 3.34/second and 3.09/second for pathologists searching for mitotic figures ( P = .222 and P = .187, respectively). There was no significant difference between the two cohorts in their accuracy in identifying the target of their search. Conclusions When searching for rare elements during a nondomain-specific search task, pathologists’ search characteristics were fundamentally different compared to nonpathologists, indicating pathologists can rapidly classify the objects of their fixations without compromising accuracy. Further, pathologists’ search characteristics were fundamentally different between a domain-specific and nondomain-specific rare-element search task.
Retention of immigrant doctors and nurses in the medical labour markets of the Nordic countries: a scoping review
Authors: Dræbel Tania Aase , Larsen Kristian , Petterson Eik Buhl , Sørensen Jane Brandt , Konradsen Flemming 
Published: November 2024

Aims: In Nordic countries, the influx of immigrant doctors and nurses has been increasing since 2005, however retention remains a challenge. The aims of this scoping review were to examine the facilitators and barriers to the retention of immigrant doctors and nurses in the Nordic countries in order to inform future studies and interventions. Method: A scoping review of peer-reviewed studies focusing on the retention of immigrant doctors and nurses in the Nordic countries was conducted using the framework developed by Arksey and O’Malley. In total, 37 studies were included. The analysis entailed both a numerical analysis to provide a descriptive view of frequencies and a thematic analysis utilising Pierre Bourdieu’s concepts of field, capital, habitus and doxa. Results: Facilitators for retaining immigrant doctors and nurses encompassed a sense of belonging, support from management and peers, collegiality, acknowledgement of diverse cultural competencies and the establishment of relevant professional networks. Barriers included unfamiliarity with local healthcare systems, discrimination, inadequate support in entry-level positions, poor psychosocial work environments, and limited professional networks. Few studies focused on the facilitators for retaining immigrant doctors or nurses, few examined the social and economic costs of immigration, and hardly any addressed the processes related to licencing, authorisation and accreditation. Conclusions: The majority of the included studies framed immigrant doctors and nurses as challenges to management or the medical labour market. The findings indicated a need for a more comprehensive and inclusive approach to health workforce management across the Nordic countries to accommodate the increasingly diverse workforce in terms of international migratory backgrounds.
Early outcomes of radical surgery in non-small-cell lung cancer patients with and without COVID-19 history: a multi-center real-world study
Authors: Pan Hanbo , Chen Hang , Li Wanyu , Tian Yu , Ge Zhen , Kong Weicheng , Gu Zenan , Zou Ningyuan , Zhu Hongda , Zhang Jiaqi , Tao Yixing , Ning Junwei , Huang Jia , Yin Hui , Zhang Ming , Zhou Chengwei , Wang Hui , Xu Guodong , Luo Qingquan 
Published: November 2024

Background: Coronavirus disease (COVID)-19 can lead to chronic lung damage and respiratory issues, potentially increasing surgical difficulty and risk for patients with non-small-cell lung cancer (NSCLC). However, the impacts of a COVID-19 history on early outcomes in NSCLC patients remain controversial. Objectives: To evaluate the effect of COVID-19 history on early outcomes in NSCLC patients and identify high-risk groups undergoing radical resection based on the largest Chinese multi-center real-world data to date. Design: Multi-center retrospective cohort study. Methods: NSCLC patients with (POCVD group) or without (NCVD group) a history of COVID-19 who underwent radical surgery at six institutions from January 2022 to January 2024 were retrospectively reviewed from a prospectively maintained database. Propensity-score matching (PSM) was utilized to minimize patient selection bias. Results: Out of 7932 cases included, PSM resulted in 3021 cases per group. The two groups were comparable regarding the proportion of male patients (52.0% vs 51.6%) and those aged ⩾70 years (13.3% vs 13.8%). Although the two groups had comparable incidences of complications with Clavien-Dindo grades ⩾II (13.0% vs 14.4%, p = 0.117), the POCVD group had longer surgical durations (120.87 ± 40.23 min vs 110.74 ± 38.76 min, mean difference (95% confidence interval (CI) = 10.13 (8.138–12.122)) and higher rates of respiratory complications than the NCVD group. Subgroup logistic regression analysis indicated that patients aged ⩾70 years (odds ratio (OR) (95% CI) = 1.322 (1.022–1.876)) and those with a smoking history (OR (95% CI) = 1.235 (1.008–1.543)) had an increased risk of developing complications with Clavien-Dindo grades ⩾II. Further analysis confirmed that these high-risk patients experienced extended surgical durations, longer chest tube drainage, and prolonged postoperative hospital stay, along with increased postoperative respiratory complications following COVID-19. Conclusion: Generally, radical resection is safe for NSCLC patients with a COVID-19 history. However, these patients experienced prolonged surgical durations and a higher incidence of postoperative respiratory complications compared to those without a COVID-19 history. In addition, individuals aged ⩾70 years or with a smoking history faced elevated surgical risks following COVID-19.