bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radiographic predictors of peritumoral brain edema in intracranial meningiomas: a review of current controversies and illustrative cases
Authors: Orešković Darko , Blažević Andrea , Kaštelančić Anđelo , Konstantinović Ivan , Lakić Marin , Murn Filip , Puljiz Marko , Štenger Martina , Barač Pia , Chudy Darko , Marinović Tonko 
Published: October 2024

AbstractMeningiomas are among the most common primary tumors of the central nervous system. In the past several decades, many researchers have emphasized the importance of radiographic findings and their possible role in predicting the various aspects of the meningioma biology. One of the factors most commonly analyzed with respect to the lesions’ clinical behavior is peritumoral brain edema (PTBE), not only one of the most common signs associated with meningiomas, but also a significant clinical problem. Radiographic predictors of PTBE are usually noted as being the size of the tumor, its location, irregular margins, heterogeneity, and the peritumoral arachnoid plane with its pial vascular recruitment. Here, we review the available literature on the topic of these radiographic predictors of PTBE formation, we analyze the methodology of the research conducted, and we highlight the many controversies still present. Indeed, the evidence about PTBE pathogenesis, predictive factors, and clinical significance still seems to be mostly inconclusive, despite intense research in the area. We believe that by highlighting the many inconsistencies in the methodology used, we can showcase how little is actually known about the pathogenesis of PTBE, which in turn has important clinical implications. Additionally, we provide several MR images of intracranial meningiomas from our own practice which, we believe, showcase the unpredictable nature of PTBE, and demonstrate vividly the topics we discuss.
Elimination of mutagenic contaminants from water using cellulose bearing ferrous-phthalocyanine
Authors: Sano Kayoko , Soga Yuka , Ohta Kaori , Kitamura Yuki , Arimoto-Kobayashi Sakae 
Published: October 2024

Abstract
Background
We previously investigated methods for separating mutagenic contaminants from aqueous solutions using cellulose-bearing covalently bound trisulfo-Cu-phthalocyanine (blue cotton and blue rayon). Mutagenic contaminants with three or more fused aromatic rings in their structures were adsorbed onto blue cotton and rayon. Since Cu-phthalocyanine is considered an unsuitable absorption ligand for byproducts of water chlorination, such as 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (Mutagen X or MX), we investigated the development of a new material for the elimination of MX from aqueous solvents.

Results
We selected green cellulose powder bearing ferrous phthalocyanine (FePh), hereafter referred to as green cellulose or GP, as the candidate material. GP is composed of cationized cellulose (white cellulose, WP) and FePh tetracarboxylic acid. The mutagenicity of MX dissolved in buffer or dimethyl sulfoxide (DMSO) solution significantly decreased after treatment with GP. The effects of GP on the elimination of MX from the solvent were very close to being expired after 70 cycles of repeated adsorption of the same GP, and the capacity of GP for MX removal was estimated to be exhausted after 120 cycles of repeated adsorption based on the extrapolation of the obtained result; thus, the interacting ligands on GP may be saturated after complete MX adsorption. The mutagenicity of MX dissolved in aqueous buffer significantly decreased after treatment at pH7.4 but not at pH 4.0. Since MX is dissociated to be the anionic form at pH 6 or higher, the negative charge of MX in the buffer at pH 7.4 may interact with the positive charge of ferrous ions in GP to create a linkage between MX and GP. After GP adsorbed MX, mutagenicity was extracted with water or acetonitrile and recovered in the eluent. Thus, the reversible interaction between MX and FePh may have caused adsorption of MX onto GP.

Conclusion
GP could be used as a new eliminator and recovery agent for MX in chlorinated drinking water. Developing new materials for the removal and recovery of agents for the detection of mutagenic contaminant-related chlorination in water is beneficial for environmental health.
The relationship between feeding practices and stunting among children under two years in Tanzania mainland: a mixed-method approach
Authors: Mandara Faith , Festo Charles , Killel Erick , Lwambura Samwel , Mrema Jackline , Katunzi Farida , Martin Haikael D. , Elisaria Ester 
Published: October 2024

Abstract
Background
Proper infant and young child feeding practices have gained attention over the years as one of the interventions to reduce childhood stunting. However, there is still a gap in research to determine these relationships in children under two years and the reasons for improper feeding.

Objective
This study aimed to assess the relationship between feeding practices, stunting and barriers among children under two years.

Methodology
Utilizing a mixed-method approach, the study involved secondary analysis of 1806 records of children aged 6–23 month, from the Next Generation Nutrition Program conducted in Tanzania (2015–2019). Both quantitative and qualitative data analyses were employed. Frequency distribution tables were utilized to describe study participants stratified by their stunting status. Subsequently, modified Poisson regression models identified predictors of stunting. Qualitative analysis encompassed deductive and inductive approaches, to extract themes that address the behaviors contributing to inappropriate feeding practices.

Results
Stunting prevalence was 28.8% among children aged 6–23 months, with the majority (65%) of stunted children aged 1 year or older. Dietary diversity was low: 88.3% and 86.3% of stunted and non-stunted children, respectively, consumed less than 5 food groups. Surprisingly, early initiation of breastfeeding, time of stopping breastfeeding, and minimum dietary diversification were not significantly associated with child stunting (p-value > 0.05). Barriers to proper feeding practices identified were inadequate knowledge of feeding, maternal condition, economic hardship, cultural issues, and seasonality.

Conclusion
Early breastfeeding and minimum dietary diversity were not significant predictors of stunting. However, the mother’s age and height > 150 cm reduced stunting risk while child sex, age, birth weight, marital status, and place of delivery also influenced stunting risk. It is crucial for initiatives to emphasize good feeding practices while addressing the complex factors that may hinder optimal feeding practices in this age group to reduce childhood stunting effectively.
Prevalence of tinnitus in temporomandibular joints disorder patients
Authors: Fadal-Allah Nourhan Gamil , Helmy Emad Saeed , Algarf Tareq Muhammad , Sheta Sarah Mohamed , Aziz Omniya Abdel 
Published: October 2024

Abstract
Background
Disorders affecting the temporomandibular joint (TMJ), related structures, and the masticatory muscles are called temporomandibular disorders (TMD). The two most typical symptoms are mouth opening restriction and pain. Costen noted the connection between TMD and tinnitus in 1934. These conditions are brought about by the shared structures that connect the TMJ and the auditory apparatus (bones and muscles) through a shared innervation source and specific ligaments. Wright addresses Costen ideas, which suggest that otological symptoms of TMD could be caused by auriculotemporal nerve damage, Eustachian tube restriction, or other factors causing an incorrect intratympanic pressure adjustment.

Methods
Cross-sectional observation was regulated at Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University. The following are the inclusion criteria: patients with a TMD diagnosis and those older than 16 years old. The following conditions are excluded: neurological or oncological disorders, ear infection, and a history of face trauma.

Results
The total number was 196 patients, 63.8% females and 36.2% males. A total of 76.5% had bilateral joint pain, and 21.9% had unilateral joint pain. While 70.4% had bilateral muscle pain, 18.9% had unilateral muscle pain. A total of 91.8% had mild tinnitus, while 8.2% had moderate tinnitus.

Conclusion
In this study, 8.2% of patients complaining of tinnitus had severe tinnitus, while 91.8% had mild tinnitus.
The role of vitamin D in the development and prevention of migraine: a review
Authors: Olszak Joanna , Zalewa Karolina , Kapłan Wojciech , Orłowska Dominika , Bartoszek Lidia 
Published: October 2024

Introduction and Purpose
Migraine is a widespread neurological disorder characterized by severe, pulsating headaches often accompanied by nausea, vomiting, and hypersensitivity to light and sound. Although its exact cause is still under investigation, recent studies suggest that vitamin D deficiency may play a role in migraine occurrence and severity. Vitamin D, known primarily for its role in bone health, also affects the nervous and immune systems, and may influence inflammatory processes involved in migraine pathogenesis. This literature review aims to explore the relationship between vitamin D supplementation and the frequency and intensity of migraines, and whether supplementation could support migraine treatment.
Material and Methods
A comprehensive literature review was conducted using the PubMed database, focusing on articles published until the end of 2023. The search included the keywords: "vitamin D," "migraine," "headache," and "supplementation" in various combinations. Relevant studies were selected based on criteria such as monitoring vitamin D levels and the use of supplementation as an intervention in migraine patients.
Results
The results of the review suggest that vitamin D deficiency may be associated with an increased frequency of migraines. Supplementation with vitamin D was linked to a reduction in both the frequency and severity of migraines. While not all studies were consistent, the majority indicated that supplementation had a positive impact, particularly in individuals with vitamin D deficiency.
Conclusions
The findings suggest that vitamin D deficiency could be a risk factor for migraines, and that supplementation with vitamin D may help reduce the severity and frequency of migraine attacks. Although further research is required to establish optimal dosages and treatment protocols, vitamin D supplementation shows promise as a supportive therapy in migraine management.
Religiosity and Attitudes towards Robots: Results from a Global Survey
Authors: Webster Craig , Ivanov Stanislav 
Published: October 2024

Religion is one lens in which people understand the world around them and interpret the world around them. However, it is unclear whether religion has an impact upon attitudes towards robots around the world. In this article, the authors investigate how an individual’s religiosity impacts upon perceptions of robots. The article investigates how an individual’s religiosity impacts attitudes towards robots, using data from a large-scale global survey of attitudes towards robots (N=1263). In order to investigate how religion impacts upon such perceptions, cluster, factor and regression analyses were used for data analysis. The findings illustrate that there are discernible clusters of individuals exhibiting different levels of religiosity and that these clusters have different perceptions of robots, showing as hypothesized, that more religious individuals are more likely to be robophobic than robophilic. The relationship between religiosity and attitudes towards robots is negative: less religious people show more positive attitudes towards robots. While there is clear indication that there is a relationship between religiosity and attitudes towards robots, religiosity does not have a particularly strong impact upon perceptions of robots. The analysis of the data illustrates that there are factors more clearly associated with perceptions of robots, meaning that while religiosity may have some impact on perceptions of robots, that there are more important attitudes and other factors that should be taken into consideration to encourage users to use robots in various service environments. In addition, in this particular research, there seems to be no notable relationship between perceptions of robots and demographics of individuals, illustrating that the age, gender, wealth, and education of an individual may not play a strong role in shaping perceptions of robots in service industries.
Exact Simulation of Quadratic Intensity Models
Authors: Qu Yan , Dassios Angelos , Liu Anxin , Zhao Hongbiao 
Published: October 2024

We develop efficient algorithms of exact simulation for quadratic stochastic intensity models that have become increasingly popular for modeling events arrivals, especially in economics, finance, and insurance. They have huge potential to be applied to many other areas such as operations management, queueing science, biostatistics, and epidemiology. Our algorithms are developed by the principle of exact distributional decomposition, which lies in a fully analytical expression for the joint Laplace transform of quadratic process and its integral newly derived in this paper. They do not involve any numerical Laplace inversion, have been validated by extensive numerical experiments, and substantially outperform all existing alternatives in the literature. Moreover, our algorithms are extendable to multidimensional point processes and beyond Cox processes to additionally incorporate two-sided random jumps with arbitrarily distributed sizes in the intensity for capturing self-exciting and self-correcting effects in event arrivals. Applications to portfolio loss modeling are provided to demonstrate the applicability and flexibility of our algorithms. History: Accepted by Bruno Tuffin, Area Editor for Simulation. Funding: This work was supported by the Beijing University of Posts and Telecommunications [Grant 2022RC58], the Shanghai University of Finance and Economics [Grant 2020110930], the National Natural Science Foundation of China [Grant 71401147], and Graduate Innovation Fund of Shanghai University of Finance and Economics [CXJJ-2023-387]. Supplemental Material: The software that supports the findings of this study is available within the paper and its Supplemental Information ( https://pubsonline.informs.org/doi/suppl/10.1287/ijoc.2023.0323 ) as well as from the IJOC GitHub software repository ( https://github.com/INFORMSJoC/2023.0323 ). The complete IJOC Software and Data Repository is available at https://informsjoc.github.io/ .
Measure Twice, Cut Once: Unit Profitability, Scalability, and the Exceptional Growth of New Firms
Authors: Tidhar Ron , Hallen Benjamin L. , Eisenhardt Kathleen M. 
Published: October 2024

By studying three promising venture pairs with different business models in different nascent markets, we explore how some new firms grow into mature firms and some promising peers do not. The successful firms first use a learning process that begins with (1) focused attention on unit profitability (not growth), then broad (not narrow) learning, and finally active delay (not acceleration) of growth. They then use a capability-building process that (2) shifts to focused attention on unit-profitable growth, then makes long-term investments in profit-oriented capabilities, and finally leverages these capabilities into new products. In contrast, peers with focused attention on growth ironically fail to achieve it. Broadly, we contribute a process theory of exceptional growth that fills the gap between the growth of new firms in the entrepreneurship literature and the growth of mature firms in the strategy and organization theory literatures. Further, we add the importance of learning content—not just learning processes—to the entrepreneurship literature on new firm growth and a rare, novel, and grounded account of the origin of capabilities to the strategy literature on the resource-based view and mature firm growth. Finally, we add to practice the significance of product–market–profit fit and a precise definition of premature scaling. Funding: This work was supported by the Strategy Research Foundation [Grant SRF-2018-DP-9167].
Pediatric cancer mortality: Analyzing early deaths and fatalities in a resource-limited tertiary care context
Authors: Farrag Ahmed , Osman Amira Mahmoud , Ghazaly Mohamed Hamdy 
Published: October 2024

Introduction
Children with suspected cancer may succumb to their bad condition shortly after admission, even before a definitive diagnosis can be reached. We aimed to address the issue of delayed presentation and early deaths among children suspected of having cancer. We analyzed also the types and causes of mortalities across different tumor types.

Materials and methods
A retrospective review of reports from newly admitted patients between 2006 and 2010 at the pediatric oncology department of the South Egypt Cancer Institute (SECI) was done. Parameters included age, gender, diagnosis, symptoms, the interval between initial symptoms and the first visit to SECI, the duration from admission to death, and the cause of death.

Results
Among the 502 patients with confirmed malignancies, 238 (47.4%) succumbed. Causes of death were predominantly treatment-related mortalities (TRM) (66%). Mortalities within hematological malignancies were mainly TRM (81%), whereas solid tumors were primarily disease-related (70%), p <0.0001. The leading causes of TRM was infection (60%).
About 5% of patients experienced early death within 48 hours after presenting to SECI. The mean duration from initial symptoms to the first SECI visit was 67 days, and the period from admission to death averaged 27 hours. Common initial symptoms included abdominal swelling (29.6%), or fever (26%). The leading causes of death were respiratory failure (29.6%), tumor lysis syndrome (22%), or septicemia (22%).

Conclusions
Delayed presentation leading to early deaths poses a significant obstacle to the successful treatment of childhood cancers. Early diagnosis and improved supportive care are essential to enhancing the overall survival, particularly in patients with hematologigical malignancies.
Performance of ChatGPT in medical licensing examinations in countries worldwide: A systematic review and meta-analysis protocol
Authors: Liu Mingxin , Okuhara Tsuyoshi , Chang Xinyi , Okada Hiroko , Kiuchi Takahiro 
Published: October 2024

Introduction
In November 2022, the online artificial intelligence (AI) chatbot ChatGPT was released to the public, and swiftly garnered global attention because of its ability to provide detailed answers to complex queries. In medical field, ChatGPT has shown great potential to be used in medical education and has excelled in many English-language medical licensing examinations. However, due to the variability of medical licensing examinations in different countries, and ChatGPT’s particular proficiency in English, the previous literatures showed that ChatGPT is unable to pass medical licensing examinations from non-English-speaking countries or those not administered in English. To the best of our knowledge, this is the first study to review whether ChatGPT can demonstrate consistent accuracy across diverse medical licensing examinations and be used in medical education across countries.

Objective
In this study protocol, we aimed to analyze and review the differences in performance of ChatGPT in medical exams in various language environments and countries, as well as its potential in medical education.

Methods and analysis
A systematic review and meta-analysis was conducted using PubMed, Web of Science, and Scopus to collect papers testing the performance of ChatGPT in medical licensing examinations. We imported all the collected literatures into Rayyan and screened the literatures based on the selection criteria and exclusion criteria. The risk of bias and quality of included studies was assessed by using Mixed Methods Appraisal Tool (MMAT). Data from included studies was extracted into an Excel spreadsheet. All of the above processes were completed by two reviewers independently. A third reviewer was consulted in cases of disagreement. Finally, we provided both quantitative and qualitative analysis of the findings from the included studies.

Trial registration
PROSPERO registration number: CRD42024506687.
Investigating academics’ attitudes towards ChatGPT: A qualitative study
Authors: Wilkinson Chelsea , Oppert Michelle , Owen Mikaela 
Published: October 2024

ChatGPT, at the forefront of artificial intelligence advancement, has caused excitement and scepticism within academic spheres due to its potential to affect academic processes. Understanding attitudes towards ChatGPT could help manage expectations and concerns for ChatGPT in academia, predict behaviour and inform policy. This study aimed to develop an understanding of university academics’ attitudes towards ChatGPT. A total of 11 university academics participated in semi-structured interviews. Data analysis found three main themes: (a) ethics, (b) changes to academic processes and (c) accessibility and inclusivity. Results showed academics had positive attitudes towards ChatGPT overall; however, they held negative attitudes towards the unethical use of the technology. Key findings included discrepancies in perceptions of academics’ personal ethical use of ChatGPT compared to unethical use by others. Furthermore, academics viewed ChatGPT as a useful tool for saving time and enhancing research processes and student learning. Finally, ChatGPT could increase equity among diverse groups, though it should be used with caution. Future studies could conduct a longitudinal study and recruit a larger and wider sample exploring specific and/or multidisciplinary domains for research diversity and the generalisability of findings.

Implications for practice or policy:

Academic policy and codes of conduct concerning the use of ChatGPT in research and education can be refined to address key ethical concerns, such as plagiarism.
Academic educators and researchers can save time and improve processes using ChatGPT to attain better work-life balance and thus potentially improve the quality of their work.
Efeito das características biométricas no rendimento da polpa do jambolão (Syzygium cumini L.) e análise da sua potencialidade nutricional e funcional
Authors: Oliveira Melo Filipe , Cypriano de Souza Luana , Martins Lemos Danielle , Silva Ribeiro Daniele , Beltrão Lessa Constant Patrícia 
Published: October 2024

O jambolão é uma planta tropical que possui frutos com características químicas e nutracêuticas ideais para exploração industrial. Objetivou-se avaliar os efeitos das variáveis biométricas do fruto no rendimento da polpa, bem como determinar a sua composição físico-química e suas propriedades funcionais. Os frutos foram adquiridos e analisados quanto as suas características biométricas, rendimento de polpa, caracterização físico-química, quantificação de compostos bioativos e potencial antioxidante, sendo os dados avaliados através de estatística descritiva, coeficiente de correlação (rS) e Análise de Componentes Principais (ACP). Observou-se que os frutos analisados apresentaram peso médio na ordem de 4,11 ± 1,06 g e diâmetro médio horizontal e vertical de 15,55 ± 2,77 mm e 27,37±7,47 mm, respectivamente. Os frutos apresentaram um rendimento de polpa médio de 65,15 ± 8,57 % e essa variável sofreu influência positiva e significativa do diâmetro horizontal (DH) (rS = 0,391) e do peso do fruto (PF) (rS = 0,493). Além disso, a polpa apresentou uma boa composição nutricional quando comparado com outras espécies frutíferas comerciais, como o teor de compostos fenólicos (45,69 ± 6,09 mg EAG /100 g), antocianinas totais (305,59 ± 106,19 mg cianidina -3 glicosídeo/100g) e atividade antioxidante (ABTS = 3.291, 92 ± 96,10 µmol equivalente a Trolox/g e FRAP = 11.876,97 ± 619 µmol Fe2SO4/100g). Conclui-se que o fruto do jambolão possui elevada potencialidade de processamento industrial, porém para que haja uma plena utilização do fruto, melhores práticas de manejo pós-colheita precisam ser adotadas, garantindo que o fruto seja utilizado com toda essa sua potencialidade.