bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones
Authors: Schroeder Nadine , Wuelling Manuela , Hoffmann Daniel , Brand-Saberi Beate , Vortkamp Andrea 
Published: May 2019

AbstractAtonal homolog 8 (Atoh8) is a transcription factor of the basic helix-loop-helix (bHLH) protein family, which is expressed in the cartilaginous elements of endochondral bones. To analyze its function during chondrogenesis we deleted Atoh8 in mice using a chondrocyte- (Atoh8flox/flox;Col2a1-Cre) and a germline- (Atoh8flox/flox;Prx1-Crefemale) specific Cre allele. In both strains, Atoh8 deletion leads to a reduced skeletal size of the axial and appendicular bones, but the stages of phenotypic manifestations differ. While we observed obviously shortened bones inAtoh8flox/flox;Col2a1-Cremice only postnatally, the bones ofAtoh8flox/flox;Prx1-Crefemalemice are characterized by a reduced bone length already at prenatal stages. Detailed histological and molecular investigations revealed reduced zones of proliferating and hypertrophic chondrocytes. In addition, Atoh8 deletion identified Atoh8 as a positive regulator of chondrocyte proliferation. As increased Atoh8 expression is found in the region of prehypertrophic chondrocytes where the expression of Ihh, a main regulator of chondrocyte proliferation and differentiation, is induced, we investigated a potential interaction of Atoh8 function and Ihh signaling. By activating Ihh signaling with Purmorphamine we demonstrate that Atoh8 regulates chondrocyte proliferation in parallel or downstream of Ihh signaling while it acts on the onset of hypertrophy upstream of Ihh likely by modulating Ihh expression levels.
Training effectiveness in an enterprise resource planning system environment
Authors: Arasanmi Chris Niyi 
Published: May 2019

Purpose
This study aims to examine the link between supervisor support, transfer motivation and post-training usage of enterprise resource planning (ERP) systems. The study tested the influence of supervisor support and transfer motivation on training transfer in a complex information systems environment. Second, the study tested the mediating effect of transfer motivation in the relationship between supervisor support and training transfer.

Design/methodology/approach
An online survey method was used to collect data from 170 ERP system users, who had previously attended ERP system training. The descriptive analysis was conducted with SPSS version 24, while Hayes Process Macro was used to test the research model and the mediation analysis.

Findings
The findings from this study showed that supervisor support and transfer motivation positively influence training transfer. The additional result also confirmed that transfer motivation mediates the relationship between supervisor support and training transfer.

Research limitations/implications
The study contributes to training theory by specifically analysing the interactions among supervisor support, transfer motivation and training transfer in a complex information system environment. One of the limitations of this study is the cross-sectional design adopted; future studies could improve by using multiple sources of data collection.

Practical implications
The study highlights the importance of social exchanges in an ERP transfer environment.

Originality/value
This paper provides a better understanding of the influences of supervisor support and transfer motivation on the transfer of hard skills in a complex environment.
Exploring the links between talent philosophies and talent management in service organizations
Authors: Pantouvakis Angelos , Karakasnaki Maria 
Published: May 2019

PurposeIn line with recent trends in the human resource management literature that address talented employees and their management, the purpose of this paper is to examine the associations between talent philosophies (innate/developable and exclusive/inclusive) and the way talent is identified and assessed in the context of service organisations.Design/methodology/approachA structured questionnaire was administered in shipping companies located in Greece and 125 questionnaires suitable for further use were collected. Moreover, the measurement instruments of the constructs under examination were adopted from relevant studies in the literature. Finally, the data were analysed through exploratory factor analysis and multiple regression analysis.FindingsThe findings showed that the different talent philosophies impact upon the way talent is managed (i.e. identified and assessed). Specifically it was found that managers who adopt mainly innate and exclusive talent philosophies tend to rely more on their first impressions in the identification of talent and to focus in a greater extent on their personal judgment rather than standardized procedures in talent assessment.Originality/valueDespite the increased academic voices on exploring the concepts of talent and talent management in the context of business organisations, the field is still lacking empirical evidence. Therefore, this study contributes to the limited empirical studies on talent issues and provides evidence on the links between the dominant talent philosophies and the way talent is identified and assessed in organisations.
Could the balanced scorecard enhance pharmaceutical organisations’ quality performance?
Authors: Elkanayati Rasha Mahmoud , Shamah Rania 
Published: May 2019

Purpose
The purpose of this paper is to investigate the relationship between balanced scorecard (BSC) attributes and quality performance and the possible moderating effect of quality performance on the relationship between BSC and business performance. The positive findings from the multinational pharmaceutical organisations in Egypt may help the national pharmaceutical companies to improve their performance when incorporating the same tool (BSC) in their quality management system.

Design/methodology/approach
This research employs a quantitative approach to conduct a survey, and empirical data were drawn from 28 multinational pharmaceutical organisations in Egypt, 125 correct questionnaires were used for further analysis, and the research model was tested using the structural equation modelling technique by analysis of moment structures software.

Findings
The findings of the empirical research reveal that the BSC attributes significantly and positively relate to quality performance where strategy translated to operations has the strongest relationship, providing feedback/learning and communication have a moderate relationship, whereas alignment relation is negligible in the presence of other attributes. Additionally, BSC attributes have a significant positive relationship with business performance directly and indirectly and quality performance is the moderator. Also, the research suggests that the quality performance has a significant and positive relationship with business performance.

Research limitations/implications
The overall research implication is that the BSC certainly acts as a ground foundation for consolidating the quality management system. The BSC practices presented in this research emphasise that this tool is not just an integration of financial and non-financial metrics that measure performance; rather, it is a performance management system that reinforces the quality system and helps to harmonise the strategy and goals that leads to improvement in the performance levels.

Practical implications
The study shows that BSC practices support the organisational quality/business performances. Therefore, managers must develop and continuously refine their strategies, allocate sufficient resources for achieving targets of strategic measures, in order to achieve superior business performance.

Originality/value
Several studies approached the effect of some of BSC attributes on quality performance; yet, this research considers the association between the four attributes collectively with quality/business performance. Additionally, no previous research has comprehensively studied the moderating effects of quality performance on the relation between BSC and business performance, especially in pharmaceutical companies in Egypt.
Correlating research impact of library and information science journals using citation counts and altmetrics attention
Authors: Ezema Ifeanyi Jonas , Ugwu Cyprian I. 
Published: May 2019

PurposeSince the development of web 2.0, there has been a paradigm shift in methods of knowledge sharing. This has equally impacted on techniques of research evaluation. Many scholars have argued that the social utilization of research is hardly reflected in the traditional methods of research evaluation. The purpose of this paper is to determine the research impact of Library and Information Science (LIS) journals using Web of Science (WoS), Scopus and Google Scholar (GS) and then examine whether there is a correlation between their citations and altmetric attentions.Design/methodology/approachThis paper is an attempt to contribute to this discussion with focus on the field of LIS. This paper adopted descriptive informatics to analyze LIS journals. The paper extracted citation data from WoS, Scopus and GS, and altmetric attentions from 85 LIS journals indexed by WoS. Further, 18 journals with high altmetric attention were identified, while 9 of these maintained consistent presence in the three databases used.FindingsFindings show that of these databases, citation data from GS was found to have a high correlation with altmetric attention, while the other two databases maintained moderate correlations with altmetric attention. The paper also found a positive but non-significant correlation between citation scores and altmetric attention in the nine journals that maintained consistent presence in the three databases.Practical implicationsThe findings of this paper will be useful to librarians in selection of relevant journals for their libraries and also will assist authors in the choice of publication outlets for their papers particularly when considering journals that have visibility and research impact.Originality/valueThe originality of the paper lies on empirical evidences from the citation and altmetric data extracted from the databases used for the paper.
A standardised flexibility assessment methodology for demand response
Authors: O’Connell Sarah , Reynders Glenn , Seri Federico , Sterling Raymond , Keane Marcus M. 
Published: May 2019

Purpose
The purpose of this paper is to standardised four-step flexibility assessment methodology for evaluating the available electrical load reduction or increase a building can provide in response to a signal from an aggregator or grid operator.

Design/methodology/approach
The four steps in the methodology consist of Step 1: systems, loads, storage and generation identification; Step 2: flexibility characterisation; Step 3: scenario modelling; and Step 4: key performance indicator (KPI) label.

Findings
A detailed case study for one building, validated through on-site experiments, verified the feasibility and accuracy of the approach.

Research limitations/implications
The results were benchmarked against available demonstration studies but could benefit from the future development of standardised benchmarks.

Practical implications
The ease of implementation enables building operators to quickly and cost effectively evaluate the flexibility of their building. By clearly defining the flexibility range, the KPI label enables contract negotiation between stakeholders for demand side services. It may also be applicable as a smart readiness indicator.

Social implications
The novel KPI label has the capability to operationalise the concept of building flexibility to a wider spectrum of society, enabling smart grid demand response roll-out to residential and small commercial customers.

Originality/value
This paper fulfils an identified need for an early stage flexibility assessment which explicitly includes source selection that can be implemented in an offline manner without the need for extensive real-time data acquisition, ICT platforms or additional metre and sensor installations.
Central bank independence, elections and fiscal policy in Africa
Authors: Agoba Abel Mawuko , Abor Joshua Yindenaba , Osei Kofi , Sa-Aadu Jarjisu , Amoah Benjamin , Dzeha Gloria Clarissa Odortor 
Published: May 2019

Purpose
The purpose of this paper is to primarily investigate the ability of independent central banks (central bank independence (CBI)) to improve fiscal performances in Africa, accounting for election years, and also to examine whether the effectiveness of CBI in improving fiscal performance is enhanced by higher political institutional quality.

Design/methodology/approach
Using recent CBI data from Garriga (2016) on 48 African countries, 90 other developing countries and 40 developed countries over the period 1970–2012, the authors apply a two stage system GMM with Windmeijer (2005) small sample robust correction estimator to examine the impact of CBI and elections on fiscal policy in Africa, other developing countries and developed countries.

Findings
The authors provide evidence that unlike in other developing countries and developed countries, CBI does not significantly improve fiscal performance in Africa. However, the effectiveness of CBI in improving fiscal performance in Africa is enhanced by higher levels of institutional quality. Although elections directly worsen fiscal performance in Africa, institutional quality enhances CBI’s effect on improving fiscal performance in election years across Africa, other developing countries and developed countries.

Practical implications
The findings of the study are significant as they provide insight into the benefits of having strong institutions to complement independent central banks in order to control fiscal indiscipline in election years.

Originality/value
The study is the first among the studies of CBI-fiscal policy nexus, to measure fiscal policy using net central bank claims on government as a percentage of GDP. In addition to the use of fiscal balance, this study also uses cyclically adjusted fiscal balance as a measure of fiscal policy. This is a critical channel through which independent central banks can constrain government spending. It also compares findings in Africa to other developing countries, noting some differences.
Assessing a social responsibility model for sustainable company growth in the Fourth Industrial Revolution
Authors: Park Sung Hyun , Shin Wan Seon , Kim Kwang Jae 
Published: May 2019

Purpose
The Fourth Industrial Revolution ( 4th IR) affects the mode of company management. This paper aims to present a revised social responsibility (SR) model as an evaluation tool for corporate social responsibility (CSR) performance for sustainable organizational growth in the era of the 4th IR.

Design/methodology/approach
To develop an SR model that can be used well in the era of the 4th IR, the key references are “ISO 26000: Guidance on Social Responsibility” and the “Global Reporting Initiative (GRI) Guidelines.” For International Organization for Standardization (ISO) 26000 and the GRI guidelines, see the homepages in the References section. On the basis of these guidelines, a new SR model for sustainable development in the 4th IR is developed in this paper.

Findings
For a new SR model in the 4th IR, the concepts of management quality (MQ), quality responsibility (QR), creating shared value (CSV), social value and open data and open quality management are incorporated into the existing ISO 26000 evaluation criteria.

Originality/value
The 4th IR is changing the concepts of both quality management (QM) and SR. To the best of the authors’ knowledge, the new concept of SR has yet to be discussed extensively. In this paper, a new SR model is suggested to reflect the characteristics of the 4th IR.
Setting the foundation for democratization
Authors: Khodary Yasmin 
Published: May 2019

Purpose
The purpose of this paper is to investigate the quality of a political science program in an Egyptian private university through assessing three particular dimensions: knowledge of political science core facts and theories; reading comprehension skills; and critical thinking (CT).

Design/methodology/approach
A case study research approach was used. The study relies also on a quantitative methodology. Quantitative data were collected from students in the second and fourth years of political science to assess their knowledge of core political science facts and theories, reading comprehension and CT through the online California Critical Thinking Skills Test.

Findings
Unlike the results of core knowledge and reading comprehension, positive results were found with regard to students’ CT. The levels of students’ CT increased from 0 percent in Year 2 to 18 percent in Year 4. Variables such as the school GPA, non-Egyptian high school degree and not meeting professors during office hours were found statistically significant to higher levels of CT.

Research limitations/implications
One limitation of the study was the relatively small samples’ size. However, while the samples might look small on the surface, they represent, in reality, between 49 and 59 percent of the students enrolled in Years 2 and 4.

Practical implications
Despite its pilot nature, this study provides some insight into the quality of private political science education in Egypt through assessing the degree it contributes to political science students’ knowledge, reading comprehension and CT and through investigating the most statistically significant variables.

Originality/value
Whilst several studies have investigated the quality of higher education programs, very limited literature attempted to assess the quality of political science education, in particular.
Linking motivation and alliance to perceived ambidexterity outcomes at the individual level in academia
Authors: Teye Emmanuel Tetteh , Abosi Beatrice Ayerakwa , Tetteh Alexander Narh , Ntim Seth Yeboah , Teye Abraham , Aseidua-Ayeh Offeibea Love , Dubi Sophia Agyeiwaa 
Published: May 2019

Purpose
Previous research has considered human motivation as a determinant of inquisitiveness, learning and innovation. However, how student’s motivation affects both exploitative/exploratory research outcomes has not yet been sufficiently addressed. The purpose of this paper is to examine self-determination theory (SDT) as a conceptual tool to understand post-graduate student’s academic motivation and how it affects two types of ambidextrous outcomes (exploitative and exploratory), and thus posit relational capital as an important mediator in the motivation–innovation process.

Design/methodology/approach
The authors draw conclusions using 331 valid post-graduate foreign scholars data collected via online survey in three Chinese Universities and conduct data analysis using the structural equation modeling technique (AMOS).

Findings
Results indicate that: academic motivation and perceived collaboration capability both has a significant effect on exploitation behavior; there was no significant relationship between academic motivation and tendency to collaborate with actors within their networks; collaboration capability and exploitation behavior mediate the relationship between academic motivation and exploration behavior; and further a complementary link was found to exist between exploitation behavior and exploration behavior in students attempt to be ambidextrous.

Originality/value
The authors advance innovation research by expanding SDT to include relational perspective as an antecedent of ambidexterity (exploration/exploitation behaviors) and provide new insights into current understanding of research engagement in higher education settings. The authors highlight some implications for educational agencies seeking to promote the emergence of psychological and relational conditions to enhance novelty in post-graduate internationalized education.
Four design principles for learner dashboards that support student agency and empowerment
Authors: Bennett Liz , Folley Sue 
Published: May 2019

Purpose
The purpose of this paper is to take a student-centred perspective to understanding the range of ways that students respond to receiving information about their learning behaviours presented on a dashboard. It identifies four principles to inform the design of dashboards which support learner agency and empowerment, features which Prinsloo and Slade (2016) suggest are central to ethical adoption of learning analytics.

Design/methodology/approach
The study involved semi-structured interviews with 24 final-year undergraduates to explore the students’ response to receiving dashboards that showed the students’ achievement and other learning behaviours.

Findings
The paper identifies four principles that should be used when designing and adopting learner dashboards to support student agency and empowerment.

Research limitations/implications
The study was based on a small sample of undergraduate students from the final year from one academic school. The data are based on students’ self-reporting.

Practical implications
The paper suggests that these four principles are guiding tenets for the design and implementation of learner dashboards in higher education. The four principles are: designs that are customisable by students; foregrounds students sense making; enables students to identify actionable insights; and dashboards are embedded into educational processes.

Originality/value
The paper’s originality is that it illuminates student-centred principles of learner dashboard design and adoption.
Money attitudes survey of business students in Kazakhstan, Kyrgyzstan and Uzbekistan
Authors: Tynaliev Urmatbek M. , Erdener Carolyn 
Published: May 2019

Purpose
The purpose of this study is to analyze the money attitudes among students at English-language business schools in the transitioning Central Asian nations of the former USSR, namely, Kazakhstan, Kyrgyzstan and Uzbekistan.

Design/methodology/approach
The survey was carried out in 2017, using previously established measures of Love of Money survey questionnaire. Over 300 undergraduate students in English-language business degree programs in Kazakhstan, Kyrgyzstan and Uzbekistan participated in the survey. A few hypotheses were tested using three-way MANOVA to test the influence of three factors (country, gender and student years). In addition, post hoc analysis, and one- and two-way ANOVA methods were used for multiple comparisons.

Findings
The results showed evidence of increasing convergence among students who are farther along in the program. Some statistically significant differences were also found, mainly in regard to gender differences in money attitudes across countries and student levels. The results of statistical analysis suggest a need for further research on attitudes and values related to money in the modern nation states of Central Asia.

Originality/value
This study is one of first attempts to study the values and attitudes regarding money among the first generation of business students who were born and grew up after their respective countries gained independence. The findings imply the development of a relatively homogeneous labor pool for business organizations across regions that are characterized by increasing differentiation among countries within the region.