bluuebunny/crossref_metadata_2025_split huggingface dataset:
Data Analysis and Validation of Acquired Temperature Data on Underwater Platform
Authors: Kumar Arun , Anjaneyulu Lokam 
Published: December 2018

<p class="western" style="margin-left: -2.25cm; margin-bottom: 0.35cm; line-height: 115%;">Underwater missiles are launched from canister by hot gasses produced by a gas generator. Hot gasses eject the missile out of canister, positioned on an underwater platform in high seas at a depth of 50 m to 70 m. During development phase of submarine launched missile, maximum number of physical parameters related to platform and launching mechanism are acquired on a data acquisition system on-board platform and selected critical parameters are transmitted to control station in real time through an optical data communication link. Missile parameters are recorded on-board and transmitted to the control station by delayed transmission technique once the missile is out of water. Exit velocity of missile is very important parameter for the missile trajectory and range, which depends upon the heat loss in canister and annular gap pressure between missile and canister during the ejection process. Prediction of exit velocity is validated by heat loss calculation by measured temperature at different stations during the test. Temperature measurement is carried out by sensors mounted on the inner wall of canister and also by jumping type of temperature sensor, which measures canister gas temperature. In spite of all efforts, few sensors do not work as expected. It is important to measure various parameters according to instrumentation measurement plan. In case of temperature measurement, sometimes, it is required to predict temperature at location, where sensor was originally not mounted. To validate the recorded test data, another set of data is needed for which one has to wait till next test is conducted that may take years and practically impossible to ensure identical test setup and environmental condition. A mathematical approach to predict temperature at required location and to validate the recorded test data is presented.</p><p class="western" style="margin-left: -2.25cm; margin-bottom: 0.35cm; line-height: 115%;"> </p><p class="western" style="margin-left: -2.25cm; margin-bottom: 0.35cm; line-height: 115%;"> </p>
Effect of two pre-freezing methods on quality of sexed semen in Ettawa Grade goat
Authors: Ondho Y.S. , Udrayana S.B. 
Published: December 2018

The aim of this study was to determine the influence of pre-freezing different procedures to the quality of Ettawa Grade goat frozen semen-sexing. The research material was semen sexing consisted of 2 layers those were top layer and bottom layer. The quality of frozen semen sexing was observed by comparing the pre-freezing technique (factory standard operating procedure: FSOP) according to the Artificial Insemination Center operating procedure (pre-freezing by placing the straw of semen for about 4 cm above liquid nitrogen for 9 minutes) with the modification procedure (MP), pre-freezing by placing the straw of semen 16 cm above liquid nitrogen for 9 minutes and then it was lowered to 4 cm above liquid nitrogen for 9 minutes during the pre-freezing phase. The parameters observed were motility, progressive motility, hyperactivation, and sperm linearity. Data were analyzed using Student's t-test.The results of this study indicated that the quality of sexed-semen in the standard operating procedures of frozen semen compared to the treatment of modifications to the top and bottom layers were motility at the top layer (46.06 ± 7.52% vs 55.6 ± 7.78%) and bottom layer (36.82 ± 6.49% vs. 41.47 ± 6.57%); progressive top layer (16.34 ± 4.27 vs. 32.83 ± 5.9%) and bottom layer 15.97 ± 2.72% vs. 19.79 ± 3.97%); hyperactivity in the top layer (0.81 ± 0.6% vs 4.09 ± 1.98%) and the bottom layer (0.71 ± 0.68% vs. 1.50 ± 1.05%); linearity consisted of linear and non-linear, the top layer (12.19 ± 2.94 vs. 20.52 ± 3.97%) and bottom layer (12.32 ± 2.63 vs 14.70 ± 2.6); while non-linear in top layer (0.14 ± 0.2 vs 0.68 ± 0.85%) and bottom layer (0.4 ± 0.13% vs 0.34 ± 0.4%). The conclusions in this study indicated that the quality of the frozen sexed-semen that has processed by pre-freezing modification technique was better than the frozen sexed-semen obtained from the Artificial Insemination Center Standard Operating procedure.
Necmettin Erbakan Üniversitesi Diş Hekimliği Fakültesi’ne Başvuran Hastaların Dental Anksiyete Düzeylerinin Değerlendirilmesi
Authors: Mağat Güldane 
Published: December 2018

Amaç: Bu
çalışmanın amacı, hastaların diş hekimlerinde yaşanan kaygı düzeylerinin
prevelansını belirlemek ve anksiyete düzeylerinin yaş, cinsiyet, eğitim düzeyi
ve diş hekimi ziyaret sıklığı ile ilişkisini değerlendirmektir.Gereç ve Yöntemler:Bu
çalışmaya Necmettin Erbakan Üniversitesi Diş Hekimliği Fakültesi’ne başvuran,
yaşları 18-85 arasında (Ortalama 36,96 ± 14,74) değişen, 404 kadın (% 53,9) ve
346 erkek (% 46,1) toplam 750 birey katıldı. Dental anksiyete düzeyini
belirlemek için Corah Dental Anksiyete Skala (CDAS) formu kullanıldı. Verilerin
analizinde tanımlayıcı istatistikten ve Ki-kare testinden yararlanıldı.Bulgular:Dental
anksiyeteye sahip birey oranı %24 (n=180) olarak saptandı. Eğitim düzeyleri ve
diş hekimine gitme sıklığı dental anksiyeteye üzerine istatistiksel olarak
etkili değilken (p&gt;0,05); yaş ve cinsiyet istatistiksel olarak etkili idi
(p&lt;0,01). Yaş azaldıkça dental anksiyete düzeyi de azalmaktaydı. Dental
anksiyete düzeyi ise bayanlarda erkeklerden daha fazla idi.Sonuçlar:Bu
çalışmanın sonuçları, dental anksiyete sahip bireylerin sayısının fazla
olduğunu göstermiştir. Yaş ve cinsiyet dental anksiyete üzerine önemli bir
faktörken diş hekimine gitme sıklığı ve eğitim düzeyi anksiyete üzerine etkili
birer faktör değildir. Diş hekimleri kadın ve genç hastaların dental anksiyete
seviyelerinin daha yüksek olduğunu göz önünde bulundurmalıdırlar.Anahtar Kelimeler:dental
anksiyete, yaş, cinsiyet
Hypothesized mechanisms through which acute exercise influences episodic memory
Authors: Loprinzi PD , Ponce P , Frith E 
Published: December 2018

Emerging research demonstrates that exercise is favorably associated with several cognitive outcomes, including episodic memory function. The majority of the mechanistic work describing the underlying mechanisms of this effect has focused on chronic exercise engagement. Such mechanisms include, e.g., chronic exercise-induced neurogenesis, gliogenesis, angiogenesis, cerebral circulation, and growth factor production. Less research has examined the mechanisms through which acute (vs. chronic) exercise subserves episodic memory function. The purpose of this review is to discuss these potential underlying mechanisms, which include, e.g., acute exercise-induced (via several pathways, such as vagus nerve and muscle spindle stimulation) alterations in neurotransmitters, synaptic tagging/capturing, associativity, and psychological attention.
The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling
Authors: Andrikopoulos Petros , Kieswich Julius , Pacheco Sabrina , Nadarajah Luxme , Harwood Steven Michael , O'Riordan Caroline E. , Thiemermann Christoph , Yaqoob Muhammad M. 
Published: December 2018

Background
During kidney fibrosis, a hallmark and promoter of CKD (regardless of the underlying renal disorder leading to CKD), the extracellular-regulated kinase 1/2 (ERK1/2) pathway, is activated and has been implicated in the detrimental differentiation and expansion of kidney fibroblasts. An ERK1/2 pathway inhibitor, trametinib, is currently used in the treatment of melanoma, but its efficacy in the setting of CKD and renal fibrosis has not been explored.

Methods
We investigated whether trametinib has antifibrotic effects in two mouse models of renal fibrosis—mice subjected to unilateral ureteral obstruction (UUO) or fed an adenine-rich diet—as well as in cultured primary human fibroblasts. We also used immunoblot analysis, immunohistochemical staining, and other tools to study underlying molecular mechanisms for antifibrotic effects.

Results
Trametinib significantly attenuated collagen deposition and myofibroblast differentiation and expansion in UUO and adenine-fed mice. We also discovered that in injured kidneys, inhibition of the ERK1/2 pathway by trametinib ameliorated mammalian target of rapamycin complex 1 (mTORC1) activation, another key profibrotic signaling pathway. Trametinib also inhibited the ERK1/2 pathway in cultured primary human renal fibroblasts stimulated by application of TGF-β1, the major profibrotic cytokine, thereby suppressing downstream mTORC1 pathway activation. Additionally, trametinib reduced the expression of myofibroblast marker α-smooth muscle actin and the proliferation of renal fibroblasts, corroborating our in vivo data. Crucially, trametinib also significantly ameliorated renal fibrosis progression when administered to animals subsequent to myofibroblast activation.

Conclusions
Further study of trametinib as a potential candidate for the treatment of chronic renal fibrotic diseases of diverse etiologies is warranted.
Motivación y realidad aumentada: Alumnos como consumidores y productores de objetos de aprendizaje. Motivation and augmented reality: Students as consumers and producers of learning objects
Authors: Marín-Díaz Verónica , Cabero-Almenara Julio , Gallego-Pérez Oscar Manuel 
Published: December 2018

La incorporación de herramientas digitales a la enseñanza supone en un gran número de casos una modificación de la actitud del estudiante hacia los contenidos. Así encontramos como la Realidad Aumentada, poco a poco se ha ido incorporando a las aulas, provocando una revolución en la forma de entender las materias a estudiar, generando una mayor motivación por parte del alumnado por desarrollar su proceso de aprendizaje. En el este artículo se presentan los resultados de la aplicación de la RA como recurso potenciador de la motivación por el aprendizaje en un grupo de alumnos de la Universidad de Sevilla del grado de Pedagogía y que cursaban la materia Tecnología Educativa. A través del modelo de Keller (1983) se ha comprobar si la utilización de esta tecnología propiciaba una mayor motivación hacia el estudio. Tras el desarrollo en el aula de una acción de innovación docente, donde los alumnos se convirtieron en consumidores y creadores de materiales y la posterior aplicación del modelo propuesto, se pudo concluir a través de los resultados alcanzados que los estudiantes participantes mostraron una mayor motivación hacia el aprendizaje de los contenidos de la materia en la que de desarrollo la investigación
Concepciones de los Docentes sobre la Evaluación Socialmente Justa
Authors: Murillo F. Javier , Hidalgo Nina 
Published: December 2018

RESUMENEl presente estudio busca conocer las concepciones de docentes sobre una evaluación socialmente justa. Para alcanzar dicho objetivo, se ha llevado a cabo una investigación fenomenográfica en la que han participado 30 docentes de educación Primaria y Secundaria, de centros públicos y privados y situados en contextos socioeconómicos favorables y desafiantes. Los resultados obtenidos muestran que los docentes conciben una evaluación socialmente justa conformada por seis elementos: una evaluación para el aprendizaje (más que del aprendizaje), equitativa y diferenciada para cada estudiante, participativa, que contribuya a la toma de conciencia social, que valore la autoestima y la empatía, y que favorezca y considere la capacidad reflexiva y critica de los estudiantes. Los hallazgos del estudio ponen de manifiesto la importancia de profundizar en concepciones sobre una evaluación socialmente justa del alumnado ya que la práctica evaluativa tiene claras repercusiones en la vida social y académica de los estudiantes.Palabras Clave: Evaluación de estudiantes, Evaluación socialmente justa, Concepciones de evaluación, Investigación fenomenográfica.ABSTRACTThe present study seeks to know assessment teachers’ conceptions about what is a socially just assessment. To achieve this objective, a phenomenographical research has been carried out in which 30 teachers of Primary and Secondary education have participated, from public and private schools located in favourable and challenging contexts. The results obtained show how teachers conceive a socially just assessment consisting of six elements: assessment for learning (rather than learning), equitable and differentiated for each student, that contributes to social awareness, which value self-esteem and empathy, and that favor and consider the reflective and critical capacity of students. The findings of our study show the importance of deepening into conceptions about a socially just assessment of students since assessment practice has clear repercussions in social and academic students’ life.Keywords: Students assessment, Socially just assessment, Assessment conceptions, Phenomenographic research.
Satisfaction degree of English teachers of Preschool and Primary Education in the Principality of Asturias
Authors: Fernández-Costales Alberto , González-Riaño Xosé Antón 
Published: December 2018

ABSTRACTThis paper analyses the satisfaction level of teachers of English in Preschool and Primary Education in the Principality of Asturias (Spain). The sample was composed of 238 teachers from 68 schools and the research tool was a 45-item questionnaire. Data were processed with SPSS, and variance analyses were performed to assess the impact of the variables considered. The main results confirm that general satisfaction is rather high, although it is possible to identify improvement proposals in relation to the social recognition of teaching, the professional status and the acknowledgement of the teaching activity by education authorities. In addition, the results show that age, educational stage, and administrative status influence teachers’ satisfaction.Keywords: Teacher satisfaction, English teachers, English as a Foreign Language (EFL), Preschool Education, Primary Education.RESUMENEste trabajo analiza la satisfacción docente de los maestros de Inglés en Educación Infantil y Primaria en el Principado de Asturias. La muestra del estudio incluye a 238 maestros de 68 centros y el instrumento de investigación fue un cuestionario de 45 ítems. Los datos obtenidos fueron procesados con SPSS y se realizaron análisis de la varianza para medir el impacto de las variables consideradas. Los principales resultados confirman que la satisfacción general de los docentes es elevada, aunque es posible identificar propuestas de mejora en relación con el reconocimiento social de la profesión, el estatus profesional, y el reconocimiento de la labor docente por parte de las autoridades educativas. Además, los resultados confirman que la edad, la etapa educativa, y el estatus administrativo tienen influencia en la satisfacción docente.Palabras Clave: Satisfacción docente, maestros de inglés, Inglés como lengua extranjera, Educación Infantil, Educación Primaria.
La publicidad con ojos de niño: imaginarios infantiles y construcción crítica de significados
Authors: Gómez-Montoya Paola Andrea , Castro Zubizarreta Ana , Aguadez Gómez José Ignacio 
Published: December 2018

RESUMENEl estudio pretende recoger la mirada infantil sobre la publicidad para comprender qué sentido e influencia tiene en la vida de los niños y en la forma de construir significado a su mundo. Los niños conviven con mensajes publicitarios, de ahí nuestro interés por recoger su mirada al respecto. Para ello, hemos contado con el apoyo voluntario de 184 niños de la ciudad de Cali (Colombia) con edades comprendidas entre los 7 y los 12 años. En esta investigación se empleó la técnica de talleres, que combinó tres actividades participativas involucrando el dibujo, la escritura y la conversación espontánea. Los resultados del estudio evidencian cómo la publicidad se ha asentado silenciosamente en la vida de los niños generando un imaginario infantil que marca un estilo de vida y una cotidianidad consumista. Términos afines a la publicidad desde la perspectiva infantil son fama, consumo y marcas. Conceptos que tienen presencia en sus aspiraciones y proyecciones. El estudio recoge lo que el niño imagina sobre el tema de la publicidad y cómo la apropia invitando a reflexionar sobre el tratamiento y la generación de prácticas educativas que fomenten que los niños lean e interpreten críticamente los mensajes publicitarios.Palabras Clave: Imaginarios, Publicidad, Procesos de escucha, Participación, Infancia.ABSTRACTThe study aims to collect the children’s perspective on advertising to understand what sense and influence advertising has in the lives of children and how to build meaning in their world. The children live with advertising messages, hence our interest to collect their eyes on it. For this, we have had the voluntary support of 184 children from the city of Cali (Colombia) aged between 7 and 12 years old. This research used the workshop technique, which combined three participatory activities involving drawing, writing and spontaneous conversation. The results of the study show how advertising has settled silently in the lives of children generating a childish imagery that marks a lifestyle and a consumerist every day. Terms related to advertising from the perspective of children with fame, consumption and brands. Concepts that have a presence in their aspirations and projections. The study gathers what the child imagines about advertising and how appropriate it inviting to reflect on the treatment and the generation of educational practices that encourage children to read and critically interpret the advertising messages.Keywords: Imaginaries, Advertising, Processes of listening, Participation, Childhood.
A biobibliographical sketch of a naturalist turned rhodologist: François Crépin (1830-1903)
Authors: Hoste Ivan , Diagre-Vanderpelen Denis 
Published: December 2018

Born in Rochefort, in the Belgian Ardennes, François Crépin (1830-1903) soon developed a taste for wild plants, yet he never received a formal training in botany. By the late 1850s, still without a job but living with his parents, the ambitious naturalist had built a large network of correspondents that included botanists in Belgium and abroad. His Manuel de la flore de Belgique, published in 1860, was an immediate and lasting success and yielded him a job as a teacher and a place in the inner circles of Belgian field botany. In the decades following its creation, in 1862, he dominated the Société royale de Botanique de Belgique and wrote numerous book reviews and papers on the flora and biogeography of Belgium. In the late 1860s, his career took a turn: he embraced the idea of evolution and started work on a world monograph of the genus Rosawhich unfortunately remained unfinished. Although rhodologists had described thousands of species, Crépin arrived at a natural classification that included no more than ca. 60 species. Before becoming director of the State Botanic Garden in Brussels, in 1876, he also did research on paleobotany.
Boekbesprekingen / Comptes rendus
Authors: Ter Sluis Rolf , Meskens Ad , Meerwijk Maurits , Theunissen Bert , Vanpaemel Geert , Vermeer Leonieke , Kleemans Machiel , Deelstra Hendrik , Van Lunteren Frans 
Published: December 2018

Esther van Gelder, Erik Jorink , Ilja Nieuwland, Marlise Rijks en Alice Spruit (red.), ‘Dingen die ergens toe dienen.’ Verhalen over materiële cultuur van wetenschap(Hilversum: Verloren, 2017), 192 pp., ill., ISBN 9789087046958. € 25. (Rolf ter Sluis)Galileo Galilei, Kijker, Kerk en Kosmos. Galileo Galilei’s ‘Bericht van de sterren’ en ‘Brief aan groothertogin Christina’, vertaald en ingeleid door Margriet Agricola, Albert van Helden en Steven van Impe (Amsterdam: Athenaeum-Polak & Van Gennep, 2017) ISBN: 9789025308384. € 19,99. (Ad Meskens)Stephen Snelders, Leprosy and colonialism. Suriname under Dutch rule, 1750 – 1950(Manchester: Manchester University Press, 2017), 288 pp., ISBN: 9781526112996. £75. (Maurits Bastiaan Meerwijk)Bert Sliggers, De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde. Herkomst en functie van het Paleontologisch en Mineralogisch Kabinet van Teylers Museum(onuitgegeven proefschrift Universiteit Leiden, 2017). (Bert Theunissen)Klaas van Berkel, Universiteit van het Noorden. Vier eeuwen academisch leven in Groningen. Deel 2. De klassieke universiteit 1876-1945(Hilversum: Verloren, 2017), 832 pp., ill., ISBN 9789087046811. € 49. (Geert Vanpaemel)Ingrid Kloosterman, Wetenschap van gene zijde. Geschiedenis van de Nederlandse parapsychologie(Amsterdam: Boom, 2017), 326 pp., ISBN: 9789024405930. € 24,90. (Leonieke Vermeer)Abel Streefland, Jaap Kistemaker en uraniumverrijking in Nederland, 1945-1962(Amsterdam: Prometheus, 2017), 320 pp., ISBN: 9789044634136. € 29,99. (Machiel Kleemans)Charles Jaumotte en René Noël, 50 ans d'histoire universitaire à Namur: des Facultés Universitaires Notre-Dame de la Paix (FUNDP) à l'Université de Namur, 1965-2015(Namen: Presses universitaires de Namur, 2017), 412 pp., ill., ISBN 9782870379035. €35. (Hendrik Deelstra)Govert Schilling, Deining in de Ruimtetijd. Einstein, zwaartekrachtgolven en de toekomst van de astronomie(Hilversum: Fontaine Uitgevers, 2017), 366 pp., ISBN 9789059567603. € 24,95 (Frans van Lunteren)
Does the Use of Intratesticular Blocks in Dogs Undergoing Orchiectomies Serve as an Effective Adjunctive Analgesic?
Authors: Fausak Erik Davis , Rodriguez Elizabeth , Simle Anna Elizabeth , Merman Netwarat , Cook Dakota 
Published: December 2018

<strong>PICO question</strong><br /><p>In dogs undergoing orchiectomy, does the use of intratesticular blocks reduce the pain in patients compared to not using intratesticular blocks?</p><strong>Clinical bottom line</strong><br /><p>Low level of evidence suggests that when compared to a pre-medication with pure-µ agonist opioids, intratesticular blocks do not appear to provide significant benefit. However, based on our clinical scenario where pre-medication is with a partial-µ opioid like buprenorphine, there may be benefit in utilising intratesticular lidocaine or bupivicaine.</p><br /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access" /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/pr-icon.jpg" alt="Peer Reviewed" />
Curriculum Integration by Projects: Opportunities and Constraints A Case Study in Systems Engineering
Authors: Mora Sonia , Coto Mayela 
Published: December 2018

The Universidad Nacional in Costa Rica is making significant efforts to improve the professional performance of graduates in order to respond to society and industry needs. In particular, the School of Informatics has been exploring the opportunities to implement, through the use of a pedagogy oriented to problems and projects, a curricular integration between diverse areas of knowledge in the curriculum.
From this perspective and with the aim of integrating the areas of programming, databases and systems engineering, an initial exploratory study was carried out with faculty members and a group of students from the fourth level of the curriculum. The findings show several limitations, such as mismatches between the course contents, lack of faculty commitment to collaborative work and student resistance. They also show the need of establishing strategies to create, from the early years of the curriculum, the necessary conditions to promote a positive attitude towards curricular integration processes and therefore overcome, at least partially, the identified limitations.