bluuebunny/crossref_metadata_2025_split huggingface dataset:
The mimesis of the on-screen interface and the essence of technology: a philosophical analysis
Authors: Pluzhnikova Natalia  Nikolaevna , Saenko Natalya Ryafikovna 
Published: December 2024

The work is devoted to the philosophical analysis of a number of culturological factors related primarily to visual genres and forms of culture, the subsequent impact of which on the rapid development of scientific and technological progress in the last decades of the XX – first decades of the XXI century directly or indirectly influenced the features of the functioning and appearance of the interface of screen devices in their now familiar form. The historically alternating cultural requirements for transformations of visual images in relation to their perception were investigated in diachrony. Through the analysis of visual culture, the authors consider modern technology as a unity of three components: technological, socio-cultural and anthropological. These components allow us to present the technique as an integral phenomenon for philosophical consideration. The research methodology is based on the use of empirical material from the field of modern technology development, and also includes an analysis of historical, philosophical and cultural sources related to the study of technology. When comparing the mimetic forms of traditional culture with the mimetic ways of reflecting the screen-type interface, a comparative typological approach is applied. The scientific novelty of the research lies in an attempt to compare the mimetic forms of traditional culture with the mimetic ways of reflecting the screen-type interface. By comparing these forms, the authors go out to study a broader phenomenon of modern society and culture – the phenomenon of technology. This research contributes to the development of the philosophy of technology in Russia. One of the tasks of the philosophy of technology is to study the subject of technical activity, which functions today as a new technical environment, in the context of digital and nanotechnology. Technical activity is the basis for the emergence of new knowledge about society. Technology acts as a form of materialization of ideas in practice, affects the development of technical sciences, all branches of knowledge in the modern world. Screen culture acts as a part of technical development based on the digitalization of technologies, but at the same time, it allows us to present technology as a unity of technology, man and society.
Real‐Time Imaging of Vaccine Biodistribution Using Zwitterionic NIR Nanoparticles
Authors: Katagiri Wataru , Lee Jeong Heong , Tétrault Marc‐André , Kang Homan , Jeong Sinyoung , Evans Conor L. , Yokomizo Shinya , Santos Sheena , Jones Catherine , Hu Shuang , Fakhri Georges El , Tsukada Kosuke , Choi Hak Soo , Kashiwagi Satoshi 
Published: June 2019

AbstractEfficient and timely delivery of vaccine antigens to the secondary lymphoid tissue is crucial to induce protective immune responses by vaccination. However, determining the longitudinal biodistribution of injected vaccines in the body has been a challenge. Here, the near‐infrared (NIR) fluorescence imaging is reported that can efficiently enable the trafficking and biodistribution of vaccines in real time. Zwitterionic NIR fluorophores are conjugated on the surface of model vaccines and tracked the fate of bioconjugated vaccines after intradermal administration. Using an NIR fluorescence imaging system, it is possible to obtain time‐course imaging of vaccine trafficking through the lymphatics, observing notable uptake in lymph nodes with minimal nonspecific tissue interactions. Flow cytometry analysis confirmed that the uptake in lymph nodes by antigen presenting cells was highly dependent on the hydrodynamic diameter of vaccines. These results demonstrate that the combination of a real‐time NIR fluorescence imaging system and zwitterionic fluorophores is a powerful tool to determine the fate of vaccine antigens. Since such non‐specific vaccine uptake causes serious adverse reactions, this method is not only useful for optimization of vaccine design, but also for safety evaluation of clinical vaccine candidates.
Colorimetric Recording of Thermal Conditions on Polymeric Inverse Opals
Authors: Lee Seung Yeol , Lee Joon‐Seok , Kim Shin‐Hyun 
Published: June 2019

AbstractRecording thermal conditions, i.e., temperature and time, is of great importance for various applications. Although thermometers can measure temperature and record its temporal change with electronic devices, they are nondisposable and not patch‐type, restricting their uses. Here, photonic films are designed that record thermal condition through irreversible structural deformation and intuitively report it with color patterns. The photonic films are inverse opals made of negative photoresist on a solid support, where the cross‐linking density of the photoresist is regioselectively adjusted. The photonic films show a gradual blueshift of structural color upon heating due to anisotropic compression of the inverse opal, of which the rate depends on temperature and cross‐linking density. For single cross‐linking density, thermal input is quantified from the color change in the form of coupled temperature and time. With multiple cross‐linking densities in a single film, the multicolor pattern is developed, from which the temperature and time are decoupled and separately estimated for isothermal condition.
Electronic Structure Characterization of Soft Semiconductors
Authors: Liu Xianjie , Fahlman Mats 
Published: June 2019

AbstractSoft semiconductors are a class of materials that have seen increased interest in terms of both basic research and development of technology, in particular optoelectronic devices. These materials, organic semiconductors and metal halide perovskites, are defined by being more mechanically malleable than the traditional crystalline inorganic semiconductors and with thin film fabrication done at lower temperatures and often from solution. In this short perspective article, basic properties of the materials are introduced, as well as their typical applications and a number of advanced characterization techniques that offer distinct advantages for studying soft semiconductor thin films.
LSPR‐Induced Catalytic Enhancement Using Bimetallic Copper Fabrics Prepared by Galvanic Replacement Reactions
Authors: Anderson Samuel R. , O'Mullane Anthony P. , Della Gaspera Enrico , Ramanathan Rajesh , Bansal Vipul 
Published: June 2019

AbstractA simple galvanic replacement (GR) reaction‐based strategy to create copper‐based bimetallic fabrics for photoreductive catalysis is reported. It is shown that a nanostructured Cu@Fabric can be easily converted into bimetallic Cu‐Au@Fabric and Cu‐Ag@Fabric through a spontaneous electroless process that involves simple exposure of copper fabrics to the aqueous solutions of gold and silver ions. The nanoscale hierarchical ordering of cotton fabrics combined with their high porosity and wettability make them outstanding supports for catalyst recovery and reusability. The deposition of miniscule quantities of expensive noble metals on readily available Cu not only reduces the overall catalyst cost, but also plays a major role in improving the catalyst stability and reusability over several cycles through minimizing Cu oxidation. The synergistic effects of the localized surface plasmon resonance (LSPR) properties of Cu, Au, and Ag allow these bimetallic fabrics into highly active visible light photocatalysts. Mechanistic investigation of the photocatalytic activity provides in‐depth information on the electron transfer processes occurring at the catalyst/ reactant interface, revealing electron transport as the rate‐limiting step, which could be overcome under visible light photoillumination conditions. The outcomes enhance the understanding of template‐supported bimetallic nanostructures for LSPR‐induced photocatalysis applications, offering new potential to design multifunctional fabrics for various applications.
C7‐Functionalization of Indoles via Organocatalytic Enantioselective Friedel‐Crafts Alkylation of 4‐Amino‐ indoles with 2‐Butene‐1,4‐diones and 3‐Aroylacrylates
Authors: Huang Tongkun , Zhao Yunlong , Meng Shanshui , Chan Albert S. C. , Zhao Junling 
Published: June 2019

AbstractAn efficient protocol for the enantioselective C7 Friedel‐Crafts alkylation between 4‐aminoindoles and 2‐butene‐1,4‐diones or 3‐aroylacrylates was reported. This process was catalyzed by a chiral phosphoric acid, affording the corresponding 1,4‐disubstituted indoles in moderate to high yields with good to high enantioselectivities. This reaction could be performed on a gram scale without loss of efficiency, and a representative derivatization of the products was also investigated to prepare the corresponding C3 formylation compound.magnified image
Strong Interplay between Sodium and Oxygen in Kesterite Absorbers: Complex Formation, Incorporation, and Tailoring Depth Distributions
Authors: Grini Sigbjørn , Sopiha Kostiantyn V. , Ross Nils , Liu Xin , Bjørheim Tor S. , Platzer‐Björkman Charlotte , Persson Clas , Vines Lasse 
Published: June 2019

AbstractSodium and oxygen are prevalent impurities in kesterite solar cells. Both elements are known to strongly impact performance of the kesterite devices and can be connected to efficiency improvements seen after heat treatments. The sodium distribution in the kesterite absorber is commonly reported, whereas the oxygen distribution has received less attention. Here, a direct relationship between sodium and oxygen in kesterite absorbers is established using secondary ion mass spectrometry and explained by defect analyses within the density functional theory. The calculations reveal a binding energy of 0.76 eV between the substitutional defects NaCu and OS in the nearest neighbor configuration, indicating an abundance of NaO complexes in kesterite absorbers at relevant temperatures. Oxygen incorporation is studied by introducing isotopic 18O at different stages of the Cu2ZnSnS4/Mo/soda‐lime glass baseline processing. It is observed that oxygen from the Mo back contact and contaminations during the sulfurization are primary contributors to the oxygen distribution. Indeed, unintentional oxygen incorporation leads to immobilization of sodium. This results in a strong correlation between sodium and oxygen, in excellent agreement with the theoretical calculations. Consequently, oxygen availability should be monitored to optimize postdeposition heat treatments to control impurities in kesterite absorbers and ultimately, the solar cell efficiency.
Propagation and Purification of Human Induced Pluripotent Stem Cells with Selective Homopolymer Release Surfaces
Authors: Jiang Siyu , Müller Mareike , Schönherr Holger 
Published: June 2019

AbstractThe selective detachment of undifferentiated human induced pluripotent stem (iPS) cells from a thermal release coating, fabricated from a tailored poly(di(ethylene glycol) methyl ether methacrylate) (PDEGMA) homopolymer layer on gold, is reported. By exploiting the mild, thermally triggered release of iPS cell colonies in the absence of any releasing reagent, pluripotent iPS cells are shown to be selectively separated from spontaneously differentiated cells. The maintained pluripotency and high cell viability of detached and reseeded iPS cell colonies were confirmed and suggest the feasibility of a generally applicable platform approach for cell separation and purification in the context of iPS cell culture, differentiation of pathologically altered cells and normal cells, as well as isolation of different cell types derived from certain tissues, for example, from biopsies.
Multicenter‐Bond‐Based Quantum Interference in Charge Transport Through Single‐Molecule Carborane Junctions
Authors: Tang Chun , Chen Lijue , Zhang Longyi , Chen Zhixin , Li Guopeng , Yan Zhewei , Lin Luchun , Liu Junyang , Huang Longfeng , Ye Yiling , Hua Yuhui , Shi Jia , Xia Haiping , Hong Wenjing 
Published: June 2019

AbstractMolecular components are vital to introduce and manipulate quantum interference (QI) in charge transport through molecular electronic devices. Up to now, the functional molecular units that show QI are mostly found in conventional π‐ and σ‐bond‐based systems; it is thus intriguing to study QI in multicenter bonding systems without both π‐ and σ‐conjugations. Now the presence of QI in multicenter‐bond‐based systems is demonstrated for the first time, through the single‐molecule conductance investigation of carborane junctions. We find that all the three connectivities in carborane frameworks show different levels of destructive QI, which leads to highly suppressed single‐molecule conductance in para‐ and meta‐connected carboranes. The investigation of QI into carboranes provides a promising platform to fabricate molecular electronic devices based on multicenter bonds.
Dehydrogenative Silylation of Alkenes for the Synthesis of Substituted Allylsilanes by Photoredox, Hydrogen‐Atom Transfer, and Cobalt Catalysis
Authors: Yu Wan‐Lei , Luo Yong‐Chun , Yan Lei , Liu Dan , Wang Zhu‐Yin , Xu Peng‐Fei 
Published: June 2019

AbstractA synergistic catalytic method combining photoredox catalysis, hydrogen‐atom transfer, and proton‐reduction catalysis for the dehydrogenative silylation of alkenes was developed. With this approach, a highly concise route to substituted allylsilanes has been achieved under very mild reaction conditions without using oxidants. This transformation features good to excellent yields, operational simplicity, and high atom economy. Based on control experiments, a possible reaction mechanism is proposed.
Inhibition of HER2‐Positive Breast Cancer Growth by Blocking the HER2 Signaling Pathway with HER2‐Glycan‐Imprinted Nanoparticles
Authors: Dong Yueru , Li Wei , Gu Zikuan , Xing Rongrong , Ma Yanyan , Zhang Qi , Liu Zhen 
Published: June 2019

AbstractBlocking the HER2 signaling pathway has been an effective strategy in the treatment of HER2‐positive breast cancer. It mainly relies on the use of monoclonal antibodies and tyrosine‐kinase inhibitors. Herein, we present a new strategy, the nano molecularly imprinted polymer (nanoMIP). The nanoMIPs, imprinted using HER2 N‐glycans, could bind almost all HER2 glycans and suppress the dimerization of HER2 with other HER family members, blocking the downstream signaling pathways, thereby inhibiting HER2+ breast cancer growth. In vitro experiments demonstrated that the nanoMIPs specifically targeted HER2+ cells and inhibited cell proliferation by 30 %. In vivo experiments indicated that the mean tumor volume of the nanoMIP‐treated group was only about half of that of the non‐treated groups. This study provides not only a new possibility to treat of HER2+ breast cancer but also new evidence to boost further development of nanoMIPs for cancer therapy.
NIR‐II Fluorescent Self‐Assembled Peptide Nanochain for Ultrasensitive Detection of Peritoneal Metastasis
Authors: Wen Qiuxiang , Zhang Yejun , Li Chunyan , Ling Sisi , Yang Xiaohu , Chen Guangcun , Yang Yang , Wang Qiangbin 
Published: June 2019

AbstractFluorescence‐guided cytoreductive surgery is one of the most promising approaches for facile elimination of tumors in situ, thereby improving prognosis. Reported herein is a simple strategy to construct a novel chainlike NIR‐II nanoprobe (APP‐Ag2S‐RGD) by self‐assembly of an amphiphilic peptide (APP) into a nanochain with subsequent chemical crosslinking of NIR‐II Ag2S QDs and the tumor‐targeting RGD peptide. This probe exhibits higher capability for cancer cell detection compared with that of RGD‐functionalized Ag2S QDs (Ag2S‐RGD) at the same concentration. Upon intraperitoneal injection, superior tumor‐to‐normal tissue signal ratio is achieved and non‐vascularized tiny tumor metastatic foci as small as about 0.2 mm in diameter could be facilely eliminated under NIR‐II fluorescent imaging guidance. These results clearly indicate the potential of this probe for fluorescence‐guided tumor staging, preoperative diagnosis, and intraoperative navigation.
Total Synthesis of Clavosolide A via Asymmetric Alcohol‐Mediated Carbonyl Allylation: Beyond Protecting Groups or Chiral Auxiliaries in Polyketide Construction
Authors: Cabrera James M. , Krische Michael J. 
Published: June 2019

AbstractThe 20‐membered marine macrodiolide clavosolide A is prepared in 7 steps (LLS) in the absence of protecting groups or chiral auxiliaries via enantioselective alcohol‐mediated carbonyl addition. In 9 prior total syntheses, 11–34 steps (LLS) were required.
Magnetic Levitation in Chemistry, Materials Science, and Biochemistry
Authors: Ge Shencheng , Nemiroski Alex , Mirica Katherine A. , Mace Charles R. , Hennek Jonathan W. , Kumar Ashok A. , Whitesides George M. 
Published: June 2019

AbstractAll matter has density. The recorded uses of density to characterize matter date back to as early as ca. 250 BC, when Archimedes was believed to have solved “The Puzzle of The King's Crown” using density.[1] Today, measurements of density are used to separate and characterize a range of materials (including cells and organisms), and their chemical and/or physical changes in time and space. This Review describes a density‐based technique—magnetic levitation (which we call “MagLev” for simplicity)—developed and used to solve problems in the fields of chemistry, materials science, and biochemistry. MagLev has two principal characteristics—simplicity, and applicability to a wide range of materials—that make it useful for a number of applications (for example, characterization of materials, quality control of manufactured plastic parts, self‐assembly of objects in 3D, separation of different types of biological cells, and bioanalyses). Its simplicity and breadth of applications also enable its use in low‐resource settings (for example—in economically developing regions—in evaluating water/food quality, and in diagnosing disease).
Inexpensive Hole‐Transporting Materials Derived from Tröger's Base Afford Efficient and Stable Perovskite Solar Cells
Authors: Braukyla Titas , Xia Rui , Daskeviciene Maryte , Malinauskas Tadas , Gruodis Alytis , Jankauskas Vygintas , Fei Zhaofu , Momblona Cristina , Roldán‐Carmona Cristina , Dyson Paul J. , Getautis Vytautas , Nazeeruddin Mohammad Khaja 
Published: June 2019

AbstractThe synthesis of three enamine hole‐transporting materials (HTMs) based on Tröger's base scaffold are reported. These compounds are obtained in a three‐step facile synthesis from commercially available materials without the need of expensive catalysts, inert conditions or time‐consuming purification steps. The best performing material, HTM3, demonstrated 18.62 % PCE in PSCs, rivaling spiro‐OMeTAD in efficiency, and showing markedly superior long‐term stability in non‐encapsulated devices. In dopant‐free PSCs, HTM3 outperformed spiro‐OMeTAD by a factror of 1.6. The high glass‐transition temperature (Tg=176 °C) of HTM3 also suggests promising perspectives in device applications.
Bismuth Compounds in Radical Catalysis: Transition Metal Bismuthanes Facilitate Thermally Induced Cycloisomerizations
Authors: Ramler Jacqueline , Krummenacher Ivo , Lichtenberg Crispin 
Published: June 2019

AbstractThe controlled radical chemistry of bismuth compounds is still in its infancy. Further developments are fueled by the properties of these complexes (e.g., low toxicity, high functional group tolerance, low homolytic bond dissociation energies, and reversible homolytic bond dissociations), which are highly attractive for applications in synthetic chemistry. Here we report the first catalytic application of transition metal bismuthanes (i.e. compounds with a Bi–TM bond; TM=transition metal). Using the catalyzed radical cyclo‐isomerization of δ‐iodo‐olefins as a model reaction, characteristics complementary or superior to known B, Mn, Cu, Zn, Sn, and alkali metal reagents are demonstrated (including a different crucial intermediate), establishing transition metal bismuthanes as a new class of (pre‐)catalysts for controlled radical reactions.
Ag10Ti28‐Oxo Cluster Containing Single‐Atom Silver Sites: Atomic Structure and Synergistic Electronic Properties
Authors: Chen Shuai , Chen Zhe‐Ning , Fang Wei‐Hui , Zhuang Wei , Zhang Lei , Zhang Jian 
Published: June 2019

AbstractSupported single‐atom catalysts have been emerging as promising materials in a variety of energy catalysis applications. However, studying the role of metal–support interactions at the molecular level remains a major challenge, primarily due to the lack of precise atomic structures. In this work, by replacing the frequently used TiO2 support with its molecular analogue, titanium‐oxo cluster (TOC), we successfully produced a new kind of Ti‐O material doped with single silver sites. The as‐obtained Ag10Ti28 cluster, containing four exposed and six embedded Ag sites, is the largest noble‐metal‐doped Ti‐O cluster reported to date. Density functional theory (DFT) calculations show that the Ag10Ti28 core exhibits properties distinct from those of metallic Ag‐based materials. This Ti‐O material doped with single Ag sites presents a high ϵd and moderate CO binding capacity comparable to that of metallic Cu‐based catalysts, suggesting that it might display different catalytic performance from the common Ag‐based catalysts, for example, for CO2 reduction. These results prove that the synergism of active surface metal atoms and the Ti‐O cluster support result in unique physical properties, which might open a new direction for single‐atom‐included catalysts.
The Buchwald–Hartwig Amination After 25 Years
Authors: Dorel Ruth , Grugel Christian P. , Haydl Alexander M. 
Published: June 2019

AbstractThe Pd‐catalyzed coupling of aryl (pseudo)halides and amines is one of the most powerful approaches for the formation of C(sp2)−N bonds. The pioneering reports from Migita and subsequently Buchwald and Hartwig on the coupling of aminostannanes and aryl bromides rapidly evolved into general and practical tin‐free protocols with broad substrate scope, which led to the establishment of what is now known as the Buchwald–Hartwig amination. This Minireview summarizes the evolution of this cross‐coupling reaction over the course of the past 25 years and illustrates some of the most recent applications of this well‐established methodology.
Diglycine Enables Rapid Intrabacterial Hydrolysis for Activating Anbiotics against Gram‐negative Bacteria
Authors: Wang Jiaqing , Cooper Deani L. , Zhan Wenjun , Wu Difei , He Hongjian , Sun Shenghuan , Lovett Susan T. , Xu Bing 
Published: June 2019

AbstractAntimicrobial drug resistance demands novel approaches for improving the efficacy of antibiotics, especially against Gram‐negative bacteria. Herein, we report that conjugating a diglycine (GG) to an antibiotic prodrug drastically accelerates intrabacterial ester‐bond hydrolysis required for activating the antibiotic. Specifically, the attachment of GG to chloramphenicol succinate (CLsu) generates CLsuGG, which exhibits about an order of magnitude higher inhibitory efficacy than CLsu against Escherichia coli. Further studies reveal that CLsuGG undergoes rapid hydrolysis, catalyzed by intrabacterial esterases (e.g., BioH and YjfP), to generate chloramphenicol (CL) in E. coli. Importantly, the conjugate exhibits lower cytotoxicity to bone marrow stromal cells than CL. Structural analogues of CLsuGG indicate that the conjugation of GG to an antibiotic prodrug is an effective strategy for accelerating enzymatic prodrug hydrolysis and enhancing the antibacterial efficacy of antibiotics.