bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Terpaan Dan Efektivitas Konten Youtube Terhadap Pemenuhan Kebutuhan Informasi Subscribers
Authors: Akbar Zheldy Abitya  
Published: August 2019

Tujuan dalam penelitian ini adalah untuk mengetahui apakah terdapat pengaruh Terpaan (X1) dan Efektivitas (X2) konten Youtube terhadap Pemenuhan Kebutuhan Informasi Subscribers (Y). Terpaan media adalah suatu perilaku seseorang (audiens) dalam menggunakan media dan efektivitas secara umum menunjukan sampai seberapa jauh tercapainya suatu tujuan yang terlebih dahulu ditentukan. Youtube adalah video online dan yang utama dari kegunaan situs ini ialah sebagai media untuk mencari, melihat dan berbagi video yang asli ke dan dari segala penjuru dunia melalui suatu web. Konten yang digunakan dalam penelitian ini adalah konten Youtube Dokter Tirta dan informasi mengenai kesehatan. Penelitian ini menggunakan pendekatan kuantitatif dengan menggunakan metode survey yaitu dengan menyebarkan kuesioner menggunakan skala likert kepada subscribers dari Youtube Channel Dokter Tirta. Teknik pengambilan sampel ditentukan dengan rumus Slovin dengan total sampel sebanyak 400 responden. Teori dalam penelitian ini menggunakan teori Uses and Gratification. Berdasarkan dari hasil analisis penelitian, (1) variabel terpaan berpengaruh signifikan terhadap pemenuhan kebutuhan informasi subscribers, (2) variabel efektivitas berpegaruh signifikan terhadap pemenuhan kebutuhan informasi subscribers, dan (3) variabel terpaan dan efektivitas signifikan terhadap pemenuhan kebutuhan informasi subscribers. Melalui cara memberikan edukasi serta informasi seputar kesehatan yang diberikan oleh Dokter Tirta serta mengikuti perkembangan kesehatan sampai saat ini, sehingga subscribers tertarik memilih konten Youtube Dokter Tirta untuk memenuhi kebutuhan informasinya mengenai kesehatan.
Improving the Speaking Ability through Role Playing Model in Learning Indonesian Language
Authors: Rosidah Ani 
Published: August 2019

This research is motivated by the students' low speaking ability in Indonesian language learning, which aims to improve students' speaking skills through the application of the Role Playing Model. This research is a Classroom Action Research (CAR) carried out in cycles II using a model from Kemmis and MC. Taggart, each action in each cycle consists of four stages, namely planning, action, observation, reflection. This research was conducted at elementary school of Rancagoong, District of Cilaku, Cianjur Regency. The subjects of this study were fourth-grade students, amounting to 24 students, consisting of 13 female students and 11 male students. Data collection techniques used are process tests, observations, interviews, and documentation. The data obtained are in the form of test results as primary data as well as observations, while the interviews and documentation as supporting data. The data analysis technique used is descriptive quantitative analysis. The results of the study show that the use of the Role Playing Model can improve students' speaking ability. This is indicated by an increase in the average value from before the action is taken until the implementation of the cycle II. The average value obtained in cycle 1 after being given action reached 66.88% with a graduation percentage of 54.17%. Then in the cycle II the average value obtained increased to 77.40% with a graduation percentage of 83.33%. In general, it can be concluded that the application of the Role Playing Model can improve students' speaking ability in learning the Indonesian Language in grade IV at Elementary school of Rancagoong, District of Cilaku, Cianjur Regency.
Pengaruh Model Pembelajaran Inkuiri Berbasis Website Terhadap Kemampuan Kognitif Siswa Kelas X Kompetensi Keahlian Multimedia Pada Mata Pelajaran Komputer dan Jaringan Dasar di SMK Negeri 2 Buduran
Authors: Maulidiyah Karina , Hasanah Fitria Nur 
Published: August 2019

This study was aimed to determine if there is influence of the website-based inquiry learning model on cognitive abilities of class and how much the influence of the website-based inquiry learning model has on the cognitive abilities of class X multimedia students expertise competencies in computer subjects and basic networks in SMK Negeri 2 Buduran. This research method used quantitative research methods Quasi Experimental Design with the design of "Nonequivalent Control Group Pretest-Posttest Design". The population in this study were 108 students of X Multimedia class 72 students as sample consisting of 36 X-TI3 students as the control class and 36 X-TI2 students as the experimental class. The instrument used in this study was the learning achievement test, where there as a pretest (which has not been treated) and posttest (which has been treated). The data obtained were then analyzed using the t-test with t count = (14,978)> t table (1,667) at a significant level of 5%. If the t count is outside the acceptance of H0, then H0 is rejected and H1 is accepted. After knowing the prettest and posttest results that have been tested to students to find out whether there is an influence or not it is done by using the analysis of N-Gain test data. From the results of the N-Gain test calculation produces 0.61 which is included in the Medium category. From the results of the study, it can be concluded that the inquiry learning model has a moderate effect on the cognitive abilities of class X multimedia students expertise competencies in computer subjects and basic networks in SMK Negeri 2 Buduran.
Analisis Kebutuhan Siswa di SMA Negeri 3 Bolo Terhadap Bahan Ajar Bergambar pada Materi Plantae
Authors: Mardiana Mardiana , Akhyar Muhammad , Musada Akhmad Arif 
Published: August 2019

Biology lesson material is closely related to the surrounding environment. To support students to be able to learn it, the media that associates academic concepts and the surrounding environment / the real world is needed. Related to this, the study aims to analyze the needs of SMA 3 Bolo students on pictured learning materials on the discussion of Plantae. The research method used is descriptive analysis and in-depth interviews, done by using questionnaire related to the learning materials used. From the results of the study, it is known that 75% of students' answers show that SMA Bolo 3 students need pictured learning materials for biology learning especially one related to plantae to create more meaningful and enjoyable learning process. This approach can direct students to understand academic concepts and have the opportunity to be directly involved in learning as well as understand the subject matter easily as learning is presented in the form of images that are easily found in their daily lives. With this, pictured Learning materials is one of the solutions in biology learning, especially in the discussion of Plantae.
Discovery and Interrogation of Functional Protein Modifications by Hotspot Thermal Profiling
Authors: Huang Jun X. , Lee Gihoon , Moellering Raymond E. 
Published: August 2019

Abstract
Hundreds of protein posttranslational modification types have been reported across diverse organisms, however we still lack methods to systematically predict, or even prioritize, which modification sites may perturb protein function under specific cellular contexts. This protocol describes a method to detect the effects of site-specific protein phosphorylation on the thermal stability of thousands of native proteins in live cells. This mass spectrometry-based protocol measures shifts in overall protein stability in response to site-specific phosphorylation sites. The resulting dataset can enable discovery of intrinsic changes to protein structure as well as extrinsic changes to protein-protein, and protein-metabolite interactions, and can help prioritize site-specific study in a high-throughput and unbiased fashion. This approach takes several days complete, can be performed with multiple samples in parallel and is applicable to diverse organisms, cell types and posttranslational modifications.
Analgesic effect of auricular point acupressure for acute pain in patients with dementia: study protocol for a randomized controlled trial
Authors: Zhang Jun-Jun , Gao Hai-Xiang , Zhang Ting-Ting , Zhang Le , Wang Yi-Ling , Dai Ya-Liang , Gao Lu-Lu , Chai Xiao-Min , Tian Tian , Zhang Wen-Jin , Tian Jian-Ying , Yu Jian-Qiang , Li Yu-Xiang 
Published: August 2019

Abstract
Aim: As many as 83% of patients with dementia living in nursing homes have complained about pain. Acute exacerbation of chronic pain in elderly patients can have a serious impact on psychology and even attempt suicide. However, the effectiveness the drugs recommended for the elderly are limited, and these older people are more prone to have drug-related side effects. The aim of this study is to identify the analgesic efficacy of auricular point acupressure (APA) for acute exacerbation of chronic pain in patients with dementia in nursing homes. Methods: The study is designed to be a randomized, sham-controlled trial and is underway in a nursing home located in northwest of China. A total of 218 dementia patients with acute exacerbation of chronic pain and a score of pain≥4 on the Changhai Pain Rating Scale is being recruited from Bangniqinchun Nursing Home in Yinchuan, China and randomly allocated to accept either an intervention or a sham-controlled group in a 1:1 ratio. While the intervention group will be given APA therapy, the other group will receive sham APP treatment. The recruiters will be assessed at baseline (T0), at 5 min (T1) during treatment, and at 5 min post intervention (T2). The primary endpoint is the Changhai Pain Rating Scale mean change for pain at T0, T1, and T2 after the initial intervention. Physiological parameters, side effects and additional use of analgesics during the intervention, satisfaction from caregivers, acceptance of patients are evaluated as the secondary outcomes. Discussions: The results of this study are expected to prove the analgesic effect of APA for acute pain in patients with dementia. If providing scientifically sound results, it will have the potential to be the basis of the evidence-based guidelines for physical therapists in clinical practice and to be implemented widely in pain patients with dementia in nursing home.
Dezocine attenuates neuropathic pain by inhibiting ERK1/2 signaling in rats
Authors: Shen Chan , Sheng Shi , Yu Ling , Xin Naixing 
Published: August 2019

Abstract
Background

Neuropathic pain severely impacts patients’ life quality. Dezocine can be used for the treatment of pain. The present study intended to explore the effects of dezocine in chronic constriction injury (CCI) induced neuropathic pain as well as the possible responsible molecules in rats.

Methods

There were 3 subgroups, ie, control group, CCI group and dezocine+CCI group. The values of paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) in rats were determined by a dynamic plantar esthesiometer. The ipsilateral lumbar spinal cords in rats were extracted for the detection of protein levels of phosphorylated-mammalian target of rapamycin (p-mTOR) and p-extracellular signal-regulated kinase 1/2 (p-ERK1/2) by western blot analysis; and the mRNA and protein expression levels of interleukin (IL)-6, tumor necrosis factor (TNF)-α, and cyclooxygenase-2 (COX-2) by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and enzyme-linked immunosorbent assay (ELISA), respectively.

Results

In comparison with control group, there were lower values of PWT and PWL in CCI group, which were partially reversed by dezocine. In addition, compared to control group, the expression levels of p-mTOR, p-ERK1/2, IL-6, TNF-α and COX-2 were upregulated by CCI, which were attenuated by dezocine.

Conclusions

In conclusion, the analgesic effect of dezocine on CCI induced neuropathic pain might be correlated with inhibiting of the p-mTOR and p-ERK1/2 signaling pathway.
Meta-analysis to Assess the Impact of Centre’s Heart Transplant Status and Volume on in-hospital Outcomes Following Extracorporeal Membrane Oxygenation for Refractory Post-cardiotomy Cardiogenic Shock
Authors: Kowalewski Mariusz , Raffa Giuseppe , Zielinski Kamil , Alanazi Musab , Gilbers Martijn , Heuts Sam , Natour Ehsan , Bidar Elham , Schreurs Rick , Delnoij Thijs , Driessen Rob , Sels Jan Willem , de Poll Marcel van , Roekaerts Paul , Meani Paolo , Maessen Jos , Suwalski Piotr , Lorusso Roberto 
Published: August 2019

Abstract
Background: Postcardiotomy cardiogenic shock (PCS) that is refractory to inotropic support remains a major concern in cardiac surgery and is almost universally fatal unless treated with mechanical support. While reported mortality rates on ECMO vary from center to center, aim of the current report is assess if the outcomes differ between centres according to volume and heart transplantation status.

Methods: A systematic search was performed according to PRISMA statement using PubMed/Medline databases between 2010 and 2018. Relevant articles were scrutinized and included in the meta-analysis only if reporting in-hospital/30-day mortality and heart transplantation status of the centre. Differences were assessed by means of subgroup meta-analysis and meta-regression.

Results: Fifty-four studies enrolling N=4,421 ECMO patients were included. Of those, 6 series were performed in non-HTx centres (204 pts;4.6%). Overall 30-day survival (95% Confidence Intervals) was 35.3% (32.5-38.2%) and did not statistically differ between non-HTx: 33.3% (26.8-40.4%) and HTx centres: 35.7% (32.7-38.8%); Pinteraction=0.531. There was no impact of centre volume on survival as well: ßcoef=0.0006; P=0.833. No statistical differences were seen between HTx and non-HTx with respect to ECMO duration, limb complications, reoperations for bleeding, kidney injury and sepsis. There were however significantly less neurological complications in the HTx as compared to non-HTx centres: 11.9% vs 19.5% respectively; P=0.009; an inverse relationship was seen for neurologic complications in centres performing more ECMOs annually ßcoef=-0.0066; P=0.031. Weaning rates and bridging to HTx and/or VADs were higher in HTx facilities.

Conclusions: There was no apparent difference in survival after ECMO implantation for refractory PCS according to centre’s ECMO volume and transplantation status. Potentially different risk profiles of patients in these centres must be taken account for before definite conclusions are drawn.
Effectiveness of additional thoracic paravertebral block in improving anesthetic effects of regional anesthesia for proximal humeral fracture surgery in elderly patients: study protocol for a randomized controlled trial
Authors: Wang Xiaofeng , Zhang Hui , Xie Zhenwei , Zhang Qingfu , Jiang Wei , Zhang Junfeng 
Published: August 2019

Abstract
Background

The innervation of shoulder-upper arm area is complicated and unclear. Ultrasound-guided brachial plexus combined with cervical plexus block is probably inadequate for the anesthesia of proximal humeral surgery. Missing blockade of T1-T2 nerves may be the reason. The primary aim of this trial is to investigate the effectiveness of additional T2 thoracic paravertebral block (TPVB) in improving the anesthetic effects of regional anesthesia for elderly patients in proximal humeral fracture surgery.

Methods

We have designed a two-armed, parallel, randomized controlled trial (RCT) to compare the anesthetic effects of ultrasound-guided brachial and cervical plexus block with or without additional T2 TPVB in terms of the following outcomes: success rate, sensory block and safety. The elderly patients over 65 years old, referred for anterior approach proximal humeral fracture surgery, will be enrolled. Each participant will be randomly assigned 1:1 to receive IC block (combined interscalene brachial plexus with superficial cervical plexus block) or ICTP block (combined thoracic paravertebral block with IC block). The primary outcome is the success rate of surgical anesthesia. The secondary outcomes are as follows: sensory block at surgical area, proportion of participants who need supplementary anesthesia (remifentanil or conversion to general anesthesia), cumulative doses of intraoperative vasoactive medications and adverse events. The necessary sample size is estimated to be 80 patients according to the data of our pilot study.

Discussion

This RCT aims to demonstrate that whether combined T2 TPVB with brachial and cervical plexus block can provide better anesthetic effects of regional anesthesia in elderly patients undergoing proximal humeral fracture surgery.
Study protocol of a randomised controlled feasibility study of food related computerised attention training versus mindfulness-training and waiting list control for adults with overweight or obesity
Authors: Beivide Daniela Mercado , Werthmann Jessica , Campbell Iain C , Schmidt Ulrike 
Published: August 2019

Abstract
Background Obesity is a highly prevalent condition with multiple adverse health consequences. Widely available first-line treatments for obesity such as dietary and other lifestyle changes typically achieve only short-term effects. Thus, new treatment approaches are needed. Novel interventions such as Attention Bias Modification Training (ABMT) and Mindfulness Based Interventions focus on modifying different maladaptive cognitive patterns typically present in people with obesity (e.g. attention bias to food cues), however, their mechanisms of action remain largely unknown. We describe the theoretical basis and the rationale for a study protocol of a feasibility randomised controlled trial (RCT) comparing two attention trainings (ABMT vs Mindfulness Training [MT]) in people with overweight or obesity. The aim of this study is to inform the development of a larger scale RCT in relation to acceptability and attendance rates and to identify preliminary evidence for the interventions’ clinical efficacy and potential underlying mechanisms. Design Forty-five adults who are either overweight or obese (minimum body mass index of 25kg/m2) will be randomly allocated to receive eight sessions over eight weeks of either computerised ABMT or MT or be on a waiting list. Clinical and cognitive outcomes will be assessed at baseline, post-treatment (8 weeks) and follow-up (12 weeks post-randomisation). These include mood, body composition and attention biases. Credibility and acceptability of the trainings will be assessed using questionnaires, and recruitment and retention rates will be recorded. Discussion Findings will inform the feasibility of developing a larger scale RCT that takes into consideration effect sizes for primary outcome measures and the acceptability of the design. The study will also provide preliminary evidence on the clinical efficacy of two different attention trainings for people with obesity and their underlying mechanisms.
Knowledge regarding antibiotic use among medical students, Medellin, Colombia: A cross-sectional study
Authors: Hguita-Gutiérrez Luis Felipe , Molina Valentina , Acevedo Jenifer María , Gómez Liceth , Villamil Gustavo Eduardo Roncancio , Quiceno Judy Natalia Jiménez 
Published: August 2019

Abstract
Background

The objective of this study was to describe the knowledge regarding antibiotic therapy of students of three medical schools of Medellín, Colombia.

Methods

The study population was made up of medical students enrolled in three universities. The instrument contained questions about their current academic term, the university the perceived quality of the education received on antibiotic therapy and bacterial resistance and specific questions on upper respiratory tract infections, pneumonia, urinary tract infections and skin and soft tissue infections. The information was analysed by calculating frequencies and measures of dispersion and central tendency. Knowledge about the treatment of each type of infection was compared with the Mann–Whitney U test and the Kruskal–Wallis H test.

Results

We included 536 medical students, 43.5% consider that the university did not train them enough to interpret antibiograms, 29.6% consider that the quality of information received on the subject at their university ranges from regular to poor. The mean score for knowledge regarding antibiotic therapy for upper respiratory tract infections was 44.2 ± 9.9 on a scale from 0 to 100. In the treatment of pneumonias, the median score was 52.9 ± 14.7, in urinary tract infection was 58.7 ± 14.8 and skin and soft tissue infections was 63.1 ± 19.4. The knowledge regarding antibiotic therapy for upper respiratory tract infections, pneumonias and urinary tract infection does not improve with academic term, the university, or perception of the education received

Conclusion

A large proportion of medical students perceive that the training received from the university is deficient regarding antibiotics and bacterial resistance, which coincides with the limited knowledge reflected in the selection of antibiotic treatment for respiratory, urinary tract, skin and soft tissue infections. Overall, the situation is the same among all universities and it does not significantly increase with academic term.
The ‘learning to learn competence’ from the Health Sciences perspective. A qualitative validation study The ‘LTL’ competence in Health Sciences. A qualitative validation study
Authors: López Bernardo Gargallo , Iranzo Àngels Cebrià i , Chust Benjamín Sarrià , Garcés Amparo Benavent , García-García Fran J. , López-Francés Inmaculada 
Published: August 2019

Abstract
Abstract
Background
‘Learning to learn’ (LTL) is a key competence proposed to education systems by the European Commission (EC, 2005). To date, no agreement on LTL has yet been reached by scholars to establish the required theoretical model to incorporate this competence into curricula. Our research team aimed to design and validate an integral model to use it as a reference. This model consisted of five dimensions; cognitive, metacognitive, affective-motivational, social-relational and ethical; and 20 subdimensions. The first three dimensions came from strategic and self-regulated learning, the fourth from the socio-cognitive approach and the fifth was an original contribution. Students, teachers, professionals and employers from Health Sciences were inquired to validate this model.
Methods
To do so, qualitative methods were used by developing four focus groups (n=20). The participants were asked a general question about LTL and their discussion was recorded. Later these tapes were transcribed and processed with Atlas ti.8. to compare the coded contents with the theoretical model. The presence and relevance of the initial model’s dimensions and subdimensions were analyzed by considering comment frequency, connection and interrelationship.
Results
The results confirmed the initial model: the participants highlighted all the dimensions and almost all the subdimensions.
Conclusions
A future research line would be to devise a standardized assessment instrument for university students based on this theoretical model. Limitations and implications for practice are discussed