bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnosing EFL writers’ development of discourse competence in disciplinary writing: an ecological approach
Authors: Wang Yumin , Xie Qin 
Published: December 2024

Abstract
This study employed a multiple-case study design to investigate nine English-as-a-foreign-language undergraduates’ disciplinary writing experiences in a bilingual teaching and learning context. Drawing on writing samples, writer’s logs, and semi-structured interviews, the study identified weaknesses in their discourse features and explored their relationships to the composing processes, immediate personal traits, and larger environmental factors. Overall, the students demonstrated a basic level of discourse competence (i.e., they could write an essay on the topic and use complex connectives accurately). However, they tended to ignore other discourse features (e.g., composing a statement to control ideas in the introduction, closing the essay with an effective conclusion, and maintaining appropriate reader-writer interactions). The data revealed a positive association between English proficiency and discourse features. Typically, those with low novice and intermediate novice proficiency levels relied on text-recognition technology to translate English materials into their L1s, thus enabling source processing. They also depended on automatic translation applications to translate their essays into English, which were written in their L1s first. Based on these findings, this study suggests the integration of adequate genre knowledge, academic reading skills, and discipline-relevant task design into L2 writing instruction and assessment practice in undergraduate study.
Lidocaine infusion for the treatment of complex regional pain syndrome: Case series and literature review
Authors: Yang Kevin J. , Mistry Porus D. 
Published: December 2024

Abstract

Introduction
Complex regional pain syndrome (CRPS) is a chronic pain condition most often triggered by direct injury to an extremity that is characterized by disproportionate pain, sensory abnormalities, and autonomic dysfunction. Early research into intravenous lidocaine therapy for CRPS has demonstrated promise, but clinical evidence remains scarce. We report on 12 patients with chronic CRPS who underwent intravenous lidocaine therapy and discuss our findings in the context of the existing literature.

Results
Patients ages ranged from 25 to 64 years. Duration of CRPS ranged from 4 to 25 years. The majority of patients (8/12, 67%) reported adequate subjective pain relief with intravenous lidocaine therapy, whereas four patients reported inadequate subjective pain relief with therapy. All patients were being treated with at least one other pharmacotherapy. Three patients experienced minor side effects.

Conclusions
Our cases, taken with existing evidence, suggest that intravenous lidocaine for the treatment of chronic CRPS is safe and may decrease the pain associated with chronic CRPS. However, this study lacks adequate sample size to make those conclusions confidently. We recommend a randomized placebo-controlled multicenter clinical trial to establish the efficacy and side effect profile of systemic intravenous lidocaine more confidently for the treatment of pain due to chronic CRPS.
Is Government Policy a Barrier or Facilitator to the Work of Place-Based Community-led Nonprofits?
Authors: Roy Michael J. , Rendall Jack , Clewett Emma , McMullan Julie , Read Rosie , McLean Jennifer , O’Hare Liam , Bertotti Marcello , Kelly Mike , Baker Rachel 
Published: December 2024

Abstract
In this paper we explore whether government policy acts as a barrier or facilitator to the work of nonprofits, and in what ways (if at all) different policy contexts influence the work of place-based community-led nonprofit organizations working to improve the health and wellbeing of their communities. Employing ‘abductive’ analysis of qualitative data collected through in-depth semi-structured interviews and focus groups with 20 non-profit leaders located in different parts of the UK, we found that government policy can act both as barrier and facilitator at various times. There is often a disconnection between policy intent and the realities of local context, funding arrangements for nonprofits was often dependent on developing and maintaining successful relationships, and there were clear tensions between the pursuit of mission and alignment to government priorities.
A promising photocathode for green hydrogen generation from sanitation water without external sacrificing agent: silver-silver oxide/poly(1H-pyrrole) dendritic nanocomposite seeded on poly-1H pyrrole film
Authors: Alnuwaiser Maha Abdallah , Rabia Mohamed 
Published: December 2024

Abstract
A novel photocathode has shown promise for generating green hydrogen from sanitation water at a rate of 50 µmol/h per 10 cm², using waste water as an electrolyte in a three-electrode cell. This photocathode is composed of two layers: a poly(1H-pyrrole) seeding layer topped with a silver-silver oxide/poly(1H-pyrrole) (Ag-Ag2O-P1HP) dendritic nanocomposite. The nanocomposite exhibits broad light absorption up to 660 nm and possesses a bandgap of 1.8 eV. SEM images reveal that the Ag-Ag2O-P1HP nanocomposite consists of well-ordered semi-spherical nanoparticles, with an average size between 80 and 100 nm. These spherical nanoparticles offer a large surface area, which enhances photon absorption and trapping efficiency. Additionally, the crystalline structure is characterized by a small crystal size of 32 nm, further contributing to the material’s efficiency. Hydrogen generation performance was evaluated by measuring the current density (J
ph) under white light and monochromatic light, compared to the dark current (J
o). The photocathode’s sensitivity was tested using four different monochromatic wavelengths: 540, 440, 340, and 730 nm. The first three wavelengths – 540, 440, and 340 nm – resulted in high J
ph values of −0.19, −0.20, and −0.21 mA/cm², respectively, indicating significant hydrogen production. Conversely, the 730 nm wavelength produced a lower J
ph value of −0.17 mA/cm², as the energy at this wavelength is insufficient to induce significant bond vibrations, resulting in limited hydrogen production. The high efficiency, combined with the straightforward fabrication of this photocathode, suggests that it could be scaled up as a prototype for industrial hydrogen generation applications.
How exercise shapes the anti-inflammatory environment in multiple sclerosis – a conceptual framework focusing on tryptophan-derived molecules in T cell differentiation
Authors: Wences Chirino Tiffany Y. , Joisten Niklas , Zimmer Philipp , Proschinger Sebastian 
Published: December 2024

Abstract
Multiple Sclerosis (MS) is a chronic neuroinflammatory autoimmune characterized by inflammation-induced lesion formation after immune cell infiltration into the central nervous system. T cells play an intriguing role in MS immunopathology and research over the past decade has shown that tryptophan (TRP)-derived metabolites are crucial molecules affecting T cell differentiation, also in MS, and are modulated by exercise. The aryl hydrocarbon receptor (AHR), for which TRP metabolites are well-known ligands, has been elucidated as main driver of T cell differentiation and an enhanced anti-inflammatory cellular milieu in human MS and preclinical mouse models. By integrating evidence from different research fields, the aim of this article is to summarize and critically discuss the potential of exercise to activate the AHR in T cells by modulating circulating TRP-derived metabolites and to provide a conceptual framework on potential benefits in MS immunopathology.
Afrikai birodalmak a Száhel-övezetben, történeti áttekintés
Authors: Búr Gábor 
Published: December 2024

Az utóbbi másfél évezredben az Atlanti-óceántól a Vörös-tengerig húzódó Száhel-övezetben birodalmak sora keletkezett, élte virágkorát, majd elenyészett. Vita tárgyát képezi, hogy ezek a birodalmak mennyiben voltak autochton fejlődés eredményei, s mennyiben a civilizációs folyosókon át érkező migráció, a kulturális diffúzió következményei. Az viszont vitathatatlan, hogy létezésük alapját a transzszaharai kereskedelem jelentette, biztosítva az erőforrásokat, a katonai fölényt. A hanyatlást is egyértelműen a fő kereskedelmi útvonalak áthelyeződése okozta, amit csak betetőzött az európai gyarmatosítás. Ezek a Száhel-övezeti birodalmak, kiemelkedő uralkodóik a mai Afrikában történelmi fogódzókat jelentenek, egy kiszipolyozott, egészen a közelmúltig alávetettségbe kényszerített kontinensen a büszkeség forrásaként szolgálnak. Jól felfogott érdek fűződik tehát az előítéletektől, a túlzásoktól, s gyakran a fantázia szüleményeitől letisztított, adekvát történelmi kép kialakításához.
Estimaci´on simultánea de la sensibilidad y la especificidad utilizando la metodolog´ía GSK en presencia de covariables
Authors: Pulzara Jessica Nathaly , Correa Juan Carlos 
Published: December 2024

Sensitivity and specificity are measures used to evaluate the performance of diagnostic tests, not only in the health sector with areas such as epidemiology, psychology, and genetics, but also in other fields such as the banking and financial sector, as well as agronomy. Sensitivity indicates the proportion of positive cases that are correctly detected by the test, in other words, sensitivity measures the effectiveness of the test when used in positive individuals, while specificity indicates the proportion of negative cases that are correctly detected by the test, i.e., it measures the effectiveness of the test when used in negative individuals. For the estimation of both quantities, various authors have proposed different methods such as the ’Gold standard’ test, Bayesian approximation, maximum likelihood, or through logistic models. However, these tests only provide marginal type estimates. In this article, we develop a procedure for simultaneously estimating sensitivity and specificity using the GSK methodology in the presence of covariates.
Consideraciones faunísticas en la transición Neolítico-Calcolítico: el yacimiento arqueológico de Papa Uvas (Huelva)
Authors: Morales Muñiz Arturo , Cereijo Pecharromán Manuel Ángel 
Published: December 2024

En el presente análisis se estudian los restos de mamíferos recuperados en el yacimiento onubense de Papa Uvas con dos fases pertenecientes al Neolítico Final y al Calcolítico respectivamente.
Aunque la química edáfica ha deteriorado mucho los restos, lo cual impide extraer conclusiones definitiva acerca de las bases de subsistencia practicadas, todo parece indicar una homogeneidad entre las cabañas de uno y otro periodo. Esta homogeneidad, además de factores culturales puede deberse a la similitud florística de la zona, como han revelado los análisis polínicos que hablan de una deforestación y antropización del lugar desde los primeros momentos de la ocupación.
On the utilization of the domestic fowl in Cenrtral Europe from the Iron age up to the Middle Ages
Authors: Benecke Norbert 
Published: December 2024

El trabajo investiga el tipo de explotación que podemos inferir se llevaba a cabo con las gallinas de Europa Central a partir de datos de 43 yacimientos arqueológicos en donde se estudia la estructura de edad de las poblaciones, la relación de sexos y el grado de dimorfismo sexual evidenciado en las osamentas.
Recent Results from Precision Measurements at the NA62 Experiment
Authors: Boboc P.-C. , On behalf of the NA62 collaboration  
Published: December 2024

Experiment NA62 at CERN collected the world’s largest dataset of charged Kaons, the main goal being the measurement of the B (K+ → π+vv- ). New results from the analyses of rare kaon and pion decays using data samples collected in 2017–2018 are presented. A sample of K+ → π+γγ decays was collected using a minimum-bias trigger and measurement of the branching ratio, study of the di-photon mass spectrum, and the first search for production and prompt decay of an axion-like particle with gluon coupling in the process K+ → π+A, A → γγ are reported. Additionally, a sample of π0 → e+e- decays was collected, using a dedicated scaled down di-electron trigger, and preliminary results for the branching ratio are reported.
Analysing physiological urinary hormonal changes in female red pandas during the breeding season
Authors: Youn Soong-Hee , Chung Dong-Hee , Jung Eun , Shin Ki-Yong , Shin Hyeon-Joo , Yang Joon-Young , Kim Kyoo-Tae 
Published: December 2024

AbstractThis study aimed to contribute to the conservation of red pandas by improving the understanding of their oestrus cycle through examining urinary hormone changes during their breeding season. To minimize stress associated with blood sample collection, we used urine samples Sex hormone levels were measured over six months in pregnant and nonpregnant red pandas, to help understand changes in oestrogen concentrations during oestrus, post-mating progesterone concentrations and differences in ceruloplasmin concentrations. The results of the study revealed that female red pandas are polyoestrous, with a second oestrogen peak after mating. Progesterone changed in a cascading fashion, peaking and then gradually declining. Successfully mated females showed higher levels of progesterone than unsuccessfully mated females, which had no peak in progesterone after mating. Ceruloplasmin was measured to confirm pregnancy, but its value as a pregnancy diagnostic factor was not confirmed. These results provide significant insights into the reproductive physiology of red pandas and lay the foundation for additional research towards improving the management and breeding strategies for this threatened species.
Infective endocarditis in injection drug users: disease course, diagnostic and clinical aspects (clinical case analysis)
Authors: Makhnyr E. F. , Kazakovtseva T. A. , Chipigina N. S. , Klimenko A. A. , Karpova N. Yu. , Anishchenko M. O. , Morits V. 
Published: December 2024

Aim. To present and clinically analyze a case of “injection drug users” infective endocarditis (IE) to increase awareness among general practitioners and cardiologists about this special variant of IE.Materials and methods. Clinical observation of a 39-year-old female patient with long-term heroin and methadone addiction, viral hepatitis C, who was diagnosed with acute primary IE caused by methicillin-sensitive Staphylococcus aureus localized on the tricuspid and mitral valves. Bilateral septic pulmonary embolism and respiratory failure, secondary anemia, thrombocytopenia, nephrotic syndrome due to secondary glomerulonephritis were observed. On the 21st day of treatment, the patient underwent tricuspid valve replacement surgery with a biological prosthesis and multicomponent reconstruction of the mitral valve, the postoperative period was complicated by the development of exudative pericarditis.Results. The clinical picture and the course of a complex case of “injection drug users” IE are discussed. The difficulties of early diagnostics of IE caused by the absence of pathognomonic clinical manifestations of the disease and the variability of the debuts of IE with the prevalence of extracardiac manifestations is highlighted. The principles of antibacterial therapy and indications for surgical treatment are reviewed.Conclusion. Clinical observation draws the attention to the high probability of diagnosing IE in cases of fever in intravenous drug users and demonstrates both the difficulties of treatment and the possibility of a favorable outcome of this serious disease with timely diagnosis, appropriate antibacterial therapy, and early cardiac surgery.
Root canal shaping in the age of minimally invasive endodontics
Authors: Sawatkar Deepti Bhagwatkar , Jain Ayushi , Advait Kolla , Aboobacker Haniya , Shaikh Musaddiqa 
Published: December 2024

: To review the advancements in root canal shaping techniques within the framework of minimally invasive endodontics (MIE) and to evaluate their impact on patient outcomes and treatment efficacy. This review synthesizes recent literature on root canal shaping, focusing on the evolution of techniques and instrumentation, including rotary and reciprocating systems. The use of cone-beam computed tomography (CBCT) in facilitating minimally invasive approaches is also discussed. MIE emphasizes the preservation of natural tooth structure, shifting away from traditional methods that prioritize extensive dentin removal. Advances in rotary and reciprocating instrumentation have enhanced the ability to shape canals conservatively while maintaining effective disinfection. CBCT imaging aids in accurate assessment of canal anatomy, thus supporting minimally invasive practices. The implementation of MIE poses challenges, particularly in achieving thorough canal disinfection without excessive dentin removal. Despite these challenges, studies indicate improved long-term outcomes for teeth treated with minimally invasive techniques, reducing the risk of fractures and enhancing tooth longevity. Minimally invasive endodontics represents a significant evolution in root canal shaping, balancing the need for effective treatment with the preservation of tooth integrity. Ongoing advancements in technology and techniques are expected to further optimize outcomes in endodontic therapy.
Impact of different light curing mode on post-operative hypersensitivity after Class I composite restorations: A randomized clinical trial
Authors: Shah Rajvi Dimple , Patel Nishtha Kiran , Shah Shilpa Samir , Kesharani Pooja R , Doshi Prerak Rakeshkumar , Shah Vyoma Dilip 
Published: December 2024

The main challenges encountered when using direct composite resins are, polymerization shrinkage and shrinkage stress, the degree of polymerization conversion, and their limited depth of cure. To overcome these challenges soft start light curing mode is preferred nowadays. To evaluate the occurrence of post-operative hypersensitivity in Class I composite restorations comparing the soft-start with the constant light curing modes using 7 generation bonding agent.Twenty patients with each having contra lateral Class I occlusal caries lesions in molars were participated. Forty Class I cavity preparations were restored with 7th generation bonding agent 7generation bonding agent (Scotchbond Universal Adhesive (3M ESPE, St Paul, USA)) and 3M™ Filtek™ Bulk Fill Flowable Restorative (3M ESPE, St Paul, USA). For each patient, one restoration was cured with soft-start mode and the contralateral restoration was cured with constant curing modes using Light Emitting Diode (LED) curing light. POH was evaluated at day 1,2&7 post-treatment using Visual Analog Scale (VAS). Data were collected and analysed by ANOVA test. Statistically significant differences were observed between the two curing modes in occurrence of postoperative hypersensitivity (P&#60;0.05). Statistical analysis revealed that incidence of POH were higher at day 1 and day 2 in constant light curing group as compared with soft start light curing group which were reduced at day 7 in both groups. Incidence of POH is seen less in soft start curing mode as compared with constant light curing mode. To reduce post-operative hypersensitivity soft start light curing mode should be used.
IMPLEMENTATION OF AN OCCLUSAL WAFER IN SEVERE MANDIBULAR FRACTURE CASES WITH POST-ORIF MALOCCLUSION: A CASE SERIES
Authors: Chintia Amelia Pratiwi  , Mirnasari Amirsyah  , Teuku Nanda Putra  
Published: December 2024

Highlights:

This study shows that occlusal wafers can effectively correct malocclusion in patients with segmental mandibular fractures after ORIF plating.
Occlusal wafers help reshape the dental arch within 2 to 4 weeks, reduce surgery time, and simplify follow-up care, making them a valuable option for surgeons.

Abstract:
Introduction: Improper treatment of severe mandibular fractures can lead to malocclusion, which poses a significant challenge for reconstructive surgeons. The occlusal wafer provides an effective solution for managing malocclusion following ORIF plating of maxillofacial fractures during the one-month postoperative evaluation period. Made from acrylic resin, the occlusal wafer serves as an intermediate guide in orthognathic surgery. It helps reposition the maxilla, adjust the mandible, and modify the jawbones to achieve ideal occlusion. The device can reshape the dental arch to any pre-planned position within 2 to 4 weeks.
Case Illustration: We present two cases of patients with segmental fractures.Case 1: A 26-year-old male also had segmental fractures of the left angle and right body of the mandible. He achieved occlusion after ORIF plating; however, malocclusion developed during the three-week follow-up. Case 2: A 28-year-old female presented with segmental fractures of the left angle and right body of the mandible. She initially achieved occlusion after ORIF plating, but malocclusion was noted during the one-month follow-up.
Discussion: Both of these patients had segmental fractures and experienced malocclusion following ORIF plating, but occlusion was achieved after occlusal wafer installation.
Conclusion: The use of an occlusal wafer facilitates optimal occlusion, streamlines the surgical procedure by reducing operating time, and enhances the ease of postoperative monitoring. This approach proves particularly valuable in cases where ORIF plating has been performed yet ideal occlusal alignment remains unachieved.
CLINICAL PROFILE AND MANAGEMENT OF HYPERTROPHIC SCARS AT DR. SOETOMO GENERAL ACADEMIC HOSPITAL SURABAYA, INDONESIA
Authors: Perdanakusuma Arda Rahmanisa , Iswinarno Doso Saputro  , Evy Evrianti  
Published: December 2024

Highlights:

Most hypertrophic scar patients were aged 17 to 25, mainly female, and the scars were mostly caused by burns on the face and upper extremities.
Surgical techniques were the most common treatment, with most scars measuring 1 to 5 cm².

Abstract:
Introduction: Scars is a prevalent clinical concern that is often more complex than commonly perceived. Hypertrophic and keloid scars results from atypical wound healing responses following trauma, characterized by an excessive deposition of connective tissue. In Indonesia, there are remains a paucity of data on the clinical profile and management of hypertrophic scars. To address this gap, researchers conducted a descriptive study to systematically examine various variables associated with hypertrophic scars, aiming to enhance understanding and inform more effective management strategies.
Methods: This research is a retrospective descriptive analysis utilizing secondary data from medical records of patients with hypertrophic scars treated at Dr. Soetomo General Academic Hospital in Surabaya during the 2019 – 2020 period. The data were collected and processed according to key variables, including age, gender, occupation, etiology, anatomical location of the hypertrophic scars, scar size, and therapeutic interventions.
Results:The number of patients with hypertrophic scars at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2019 to 2020 was 68. Most patients were aged 17 to 25 years. The gender distribution was nearly equal, with 50% male and 50.9% female patients. Among the patients, 12.5% and 43% were students. Burns caused 37.5% and 25% of cases. The most common scar locations were the face (25%) and upper extremities (25%). Most scars measured 1 to 5 cm² (25%). The most common treatment was surgical techniques (80% and 48%).
Conclusion: Most hypertrophic scar patients were aged 17 to 25 years, predominantly female, and students. The primary cause of the scars was burns, with the scars most commonly located on the face and upper extremities. The majority of scars measured between 1 and 5 cm², and surgical techniques were the most widely used therapy.