bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasminogen Activity in Plasma and in Serum Before and After Venostasis
Authors: Soria C. , Rodriguez-Zeballos A. , Soria J. , Kartalis G. 
Published: May 2019

When venostasis is applied in men for 10 minutes at a pressure half-way between diastolic and systolic, various results may be obtained as far as fibrinolysis is concerned, normally the euglobulin lysis time reduced from above 3 hours to less than one hour. In these conditions, after venostasis the estimation of plasminogen after activation by Streptokinase (S.K.) on synthetic substrate S2251, shows 20-80% greater activity in serum than in plasma. In some patients at high risks of thrombosis, the euglobulin lysis time 15 unchanged after venostasis. In these cases, the biological activity of plasminogen is slightly greater in plasma than in serum, as is observed before venostasis in all subjects.In order to explain these observations, experiments were performed using placental or plasmatic (glu or lys) plasminogen ; these show that for the same antigen activity, the biological activity of placental plasminogen previously activated by S.K. is greater than that of plasmatic plasminogen. We suggest a modification of the structure of plasminogen in the presence of activators and of fibrin clots. Further experiments will be necessary to explain the modification of plasminogen structure
Immunoradiometric Assay for VIII:CAg BASED on Two Non-Haemophilic Antibodies
Authors: Holmberg L. 
Published: May 2019

Antihaemophilic-factor-A-antibodies, which had spontaneously arisen in two patients, were used to develop an imtiunoradiometric method for measurement of antihasnophilic factor A antigen (VIII:CAg). One of the antibodies was used for ooating plastic tubes. A seaond antibody formed a stable high molecular weight complex with a factor VIII-concentrate and could conveniently be isolated in labelled form. This antibody, which seated to be bound to only one immunologie site of VIII:CAg, was used for detecting the VIII. CAg fixed to the tubes by the first antibody.Thirteen patients with severe haancphilia A had VIII:CAg below the limit of detection (0.01 U/ml). Patients with moderate and mild haemophilia A either had VTII:CAg roughly equal to factor VIII clotting activity (VIII:C) or a not detectable VTII. CAg, suggesting two different molecular mechanisms in moderate and mild hasrophilia. VIII:CAg oould be detected in serum but in lower amounts than in plasma. In two patients with von Willebrand’s disease VIII:CAg equalled VIII.C. The post-transfusional retarded increase of VIII :C in a patient with von Willebrand’s disease was accompanied by a slight increase in VIII. CAg. Fetal plasma contained measurable amounts of VIII. CAo.
Biophysical Factors of Thrombosis
Authors: Stoltz J.F. 
Published: May 2019

In addition to patiental anf blood factors, Virckow’s classical trial includes stasis which combined with one of the others factors, may cause venous or arterial thrombosis. The author successively consider hempdynamic biophysical factors and rheological factors related to blood.With regard to hemodynamic factors attention is drawn to the incidence of thrombosis from local modifications of blood flow. The type of flow should also be considered and the risk of thrombosis increases in presence of turbulence, areas of recirculation or Vortex. With record to blood factors, hyperviscosity must be taken into account and particular attention should be paid to increase of haematocrit, intravascular aggregation of bloos cells (sludge) globular factors (membrane elasticity and internal viscosity) and interaction of blood cells on platelets.Atheromatous deposits on white thrombi may also obey certain rheological parameters (irregularities in the vascullar wall, changes in the juxtaparietal layer, microturbulence, stanating areas...) Lastly, with regard to vascular wall, in addition to biochemical and haemotologic changes, account must be taken of parietal viscoelasticity, electrial charge of the vascular wall...This work was supported by DRET (Biological department) Grant 78 34.097.00.480.01
Platelet Survival Half-Life in Diabetes Mellitus with and without Peripheral Arterial Occlusive Disease
Authors: Kazmier F.J. , Fuster V. , Chesebro J.H. , O’Fallon W. M. , Palumbo P.J. 
Published: May 2019

A role for the platelet has been suggested in the pathogenesis and complications of atherosclerosis and diabetes mellitus. Accordingly, as part of a large prospective study on diabetes mellitus, platelet consumption was estimated by 51Cr platelet survival halflife in 4 groups of subjects over age of 50: (1) in 20 control apparently normal individuals free of known risk factors for atherosclerotic disease, (2) in 25 patients (pts) with diabetes, (3) in 29 pts with clinical and objective evidence (by transcutaneous Doppler ultrasound studies) of peripheral arterial occlusive disease (PAOD), and (4) in 28 pts with both diabetes and PAOD.vs. control:* = 0.03, # p = 0.02, ** p < 0.001In conclusion, platelet survival was significantly short in 3 groups of pts:in those with diabetes mellitus alone, in those with PAOD and in those with diabetes mellitus associated with PAOD. This data further supports the role of platelets in the pathogenesis and complications of atherosclerosis and diabetes mellitus.
Localization of the α-Chain Cross-Linking Sites in Human Fibrinogen
Authors: Hessel B. , Savidge G. , Blombäck B. 
Published: May 2019

Antisera were raised in rabbits against the fragments Hi2-DSK and N-DSK obtained from cyanogen bromide treatment of human fibrinogen. Sensitive radioimmunoassay techniques were developed to quantitate substances sharing the same antigenic determinants as these fragments. We have found that the cross-linking process in fibrin formation involves the Hi2-DSK region which has its origin in the Aα-chain of fibrinogen. This relationship is based upon the following experimental data: - Fibrin samples produced in the presence and absence of Factor Xllla and Ca++ and thus cross-Linked and non cross-linked respectively were treated with cyanogen bromide. The resulting degradation products were chroraatographed on Sephadex G-100, and radioimmunoassays for Hi2-DSK and N-DSK were performed on the eluates. The elution profiles of Hi2-DSK and N-DSK antigenic determinants demonstrated that Hi2-DSK eluated after N-DSK in non cross-linked fibrin samples but in the cross-linked samples Hi2-DSK eluated before N-DSK. These results demonstrate that the Hi2-DSK region is involved in the cross-linking process in the presence of Factor XIIIa and calcium ions. Fibrin samples produced in the coagulation of whole blood showed a similar cross-linking profile.Supported by The Bank of Sweden Tercentenary Foundation.
Sex Differences in Platelet Response to Aspirin
Authors: Coppe D. , Harris W.H. , Ransil B.J. , Salzman E.W. 
Published: May 2019

To understand the reported (NEJM 297:1246; 299:53) sex difference in antithrombotic effectiveness of aspirin (ASA), we studied ASA pharmacokinetics and ASA’s effect on hemostasis and platelet function in patients undergoing totai hip replacement who received either 1.2 gm or 3.6 gm daily. Platelets from women aggregated more with epinephrine and collagen than did those from men, and, although ASA inhibited aggregation in both sexes, the sex difference persisted after ASA. The response did not correlate with ASA dosage. Serotonin release was initially greater with platelets from females but was abolished by ASA in both sexes. Platelet counts were higher in women (p<0.05). There was no sex difference in platelet malondialdehyde production or its inhibition by ASA or in basal values or ASA’S effect on bleeding time or fibrinolytic activity in whole blood. Serum ASA esterase activity was similar in the two sexes. Plasma salicylate levels were higher in women.No difference was observed in ASA’s effect in the two sexes. The sex difference in the antithrombotic efficacy of aspirin may relate to ASA’s failure to eliminate the preexistent sex difference in platelet count and aggregability.
Blood Fibrinolysis in Subjects with Risk Factors and in Patients with Peripheral Atherosclerotic Arterial Disease
Authors: Steqnar H. , Accetto B. 
Published: May 2019

Depressed fibrinolysis is common in subjects with risk factors for atherosclerosis as well as in patients with peripheral atherosclerotic arterial disease (PAAD). In order to establish changes in fibrinolysis related either to risk factors alone or to PAAD, separate components of the fibrinolytic enzyme system were studied in the plasma of 13 young males, in 11 males with risk factors and in 34 natlents with PAAD, arranged into 3 qro-ups according to the progression of the disease.Results show lower plasminogen activator activity, higher antiurokinase activity, higher fibrinogen and flbrinogen/fIbrin degradation product concentrations in risk and PAAD groups compared to the healthv controlsFurther significant changes in PAAD rtroups were observed in fibrinogen, total antlplasmln and alpha-1-antitrypsin activity, beina most pronounced in th. most advanced PAAD group.From the results we concluded that fibrinolysis in PAAD is depressed due to elevated levels of plasmin Inhibitors in addition to chances already observed in subjects with risk factors. High concentration of fibrinogen probably favours progression of the disease.
Platelet Prostaglandin F2α(PFG2α) in Atherosclerosis
Authors: Gürsoy Ayla , Alev Ozbllen , Ulutin Orhan N. 
Published: May 2019

This study was done with the clinically evaluated atherosclerotic cases that showed hyperaggregability, hypersecretion and increased adhesion of platelets, as well as platelet phospholipid changes. Using radio immunoassay (RIA) we have measured PGF2α which was formed by human platelet in response to collagen. Synthesis of PGF2α by freeze-thawed platelets and in platelet rich plasma (PRP) incubated with different amounts of collagen were also investigated.Incubation of atherosclerotic patients’ PRP with collagen at 37°C for 5 minutes showed an increase in the amount of PGF2α compared to normal controls.
A dual-band cold-electron bolometer with on-chip filters for the 220/240 GHz channels of the LSPE instrument
Authors: Kuzmin L S , Pimanov D A , Gordeeva A V , Chiginev A V , Masi S , de Bernardis P 
Published: May 2019

Abstract
We are developing multi-chroic double-slot antenna with cold-electron Bolometer (CEB) on-chip filters for the 220/240 GHz interstellar dust monitoring channels of the LSPE–SWIPE experiment. For this goal, we used a narrowband double-slot resonant antenna with CEBs connected by coplanar lines. The simulations show that we have achieved 5% bandwidth for 220 GHz and 5.5% bandwidth for 240 GHz in our numeric modeling for the single cells. A series array of unit cells using double-slot design and coplanar lines with CEBs shows proper frequency selection. Estimations of the noise properties of the CEB arrays in a voltage-biased mode with the SQUID readout show photon-noise limited operation for the optical power load of 6 pW for channel 220 GHz and 20 pW for channel 240 GHz.
The effects of acute exposure to cadmium nitrate (CdNO3) on gambusia fish (Gambusia affinis)
Authors: Adam M A , Maftuch  , Kilawati Y , Soegianto A , Risjani Y 
Published: May 2019

Abstract
The aim of this study was to assess the impact of cadmium nitrat (CdNO3) in Gambusia affinis on growth and the development of histopathological changes in gill organs and on the activity of some oxidative stress markers during a 96-hours acute toxicity test. Tests were performed on G. affinis. The average initial weight of fish used in the experiment was 3±1.2 g and the average initial total length of fish was 5.21±3.48 mm. The fish were exposed to a range of CdNO3 concentrations (1 mg/L, environmental concentration, 0.1, 0.01, 0.001 nad 0.0001 mg/L) for 96 hours. Each test on a CdNO3-treated group was performed in duplicate. There were no significant differences between the specific growth rates of fish from the test groups and from the control group. Histopathological examination revealed no pathological changes in organs of fish exposed to any CdNO3 concentration. Significantly lower CAT and SOD activity (p<0.05, p<0.01) was found in fish exposed to CdNO3 concentrations of 1, 0.1 and 0.01 mg/L compared to the control group; the control group was observed. H2O2, GSH and GPx exhibited significantly higher activity (p<0.01) in the 1, 0.1, 0.01 and 0.001 mg/L groups compared to the control group. But none of these differences were significant (p>0.05). No significance differences (p>0.05) between the control group and any experimental group were found with respect to Protease activity. The MDA level was significantly higher (p<0.01) at a concentrations of 1, 0.1, 0.01 and 0.001 mg/L compared to the control, while in the other experimental groups no significant differences compared to the control group (p>0.05) were observed. According to our results, all tested concentrations of CdNO3, including the environmental concentration, had an inhibit on oxidative stress markers and detoxifying enzymes in exposed fish, but did not affect fish growth or cause the development of histopathological changes in the fish organism.
PH (piezoelectric on hydraulic ram pump) media supplier of water and producing electrical energy environment-friendly
Authors: Dienullah R M A , Aini F K , Febriana F , Rosariawari F 
Published: May 2019

Abstract
Water and electricity are some of the most important components of human life in this 20th century, both in daily activities and in work. Water and electricity are also resources that should be massively exploited for the benefit to be felt by all elements of society. However, problems occur when geographical factors and infrastructure factors become an obstacle in supporting the availability of these resources. Geographical factors in the form of areas far from water sources, as well as the location of areas far from the reach of the government so that there is a gap in the development in the distribution of infrastructure within a region. This causes some elements of society, especially in backward villages, cannot benefit fully from these resources. To overcome the crisis, we try to innovate by making a development of a hydraulic ram (hydram) pump by adding piezoelectric material as a source of electricity. Then, we will put the piezoelectric material into the series of hydram pump so that the rural community will be left behind will be able to feel the water and electricity resources of our innovations are simultaneously environmentally friendly.
Pressure drop investigation of industrial scale cyclone for palm oil fiber boiler
Authors: Pratiwi I A , Ardiansyah H D 
Published: May 2019

Abstract
Higher of production of palm oil will be followed of industrial mill especially biomass boiler utilization. Environment issue can reduce with dust collector installation. The most favorite dust collector in palm oil boiler is cyclone. Investigation of pressure drop for biomass boiler is very critical due to relate with boiler performance. Cyclone as dust collector of biomass boiler has big portion of pressure static reduction. The purpose of this present study is to observe the good prediction of pressure drop with industrial scale cyclone. Some approach have been calculated and evaluate with the experiment of cyclone boiler in palm oil mill.
Simulation of pollution load capacity using QUAL2Kw model in Kali Surabaya River (Cangkir-Sepanjang segment)
Authors: Aliffia A , Karnaningroem N 
Published: May 2019

Abstract
The Utilization of Kali Surabaya River as water resources for drinking water is constrained by pollution from domestic and industrial waste and agricultural activities around the river banks. This study was aimed to calculate the pollution load capacity using QUAL2Kw model which presented the water quality. Study area from upstream (Cangkir) to downstream (Sepanjang) of the river was divided into 3 segments. The required data included primary data by sampling at determined points representing the condition of pollutant source. Secondary data included climatology, population, river hydraulic, and discharge and quality of pollution obtained from related institution. The water quality parameters analysed were BOD and COD, where the result exceeded the water quality standard of class I, while the DO was less than the standard requirement. Based on the simulation result, the value of pollutant load in each segment for BOD was 12,416 kg/day, 23,180 kg/day, and 17,759 kg/day while COD was 56,158 kg/day, 99,188 kg/day, and 74,316 kg/day. Then, the capacity of BOD in each segment was 1,681 kg/day, 1,138 kg/day, and 1,398 kg/day while COD is 12,396 kg/day, 8,150 kg/day, and 9,681 kg/day. This means that the pollutant load has exceeded the capacity of the river.
Distribution mapping of Open Defecation (OD) houses in East Surabaya based on Geographic Information System (GIS)
Authors: Purnama M Y , Soedarti T , Oktavitri N I , Fitriani N 
Published: May 2019

Abstract
The purpose of this study is to know and locate the distribution of open defecation houses in East Surabaya of Surabaya City, Indonesia. Both of secondary and primary data are required for this research, the secondary data consist of the number of OD houses in East Surabaya and basic map of Surabaya City. Primary data consist of field survey OD houses of legal and illegal status. Mapping is conducted with mapping software based on geographical information system. The result of this research proves that there are 1.083 OD houses in East Surabaya and it is equally distributed throughout East Surabaya. The most OD sub-district (Kelurahan) is Gubeng with approximately 319 houses while the least is Kelurahan Tambaksari with 23 houses.
Save the Forest and Biodiversity: A Cultural Anthropology Perspectives on Kalumpang Customary to Preserve their Ecological Living
Authors: Asba A R , Rahman F , Evita A L 
Published: May 2019

Abstract
The ecological life intended in this research review is everything related to the protection and preservation of the planet’s environment with various ecosystems and species in it. Whether we realize it or not, each habitat naturally contributes to all aspects of human ecology. No exception with Kalumpang people. The objective of this paper is to review the formulated formulas: 1) provides an overview of the patterns of life of the Kalumpang indigenous people in their interactions with nature, 2) identifies the myths and pamali believed by the indigenous Kalumpang people related to natural management, and 3) reveals the conservation model forest based on local wisdom (myths & pamali) which they inherited from generation to generation. This study uses a cultural anthropology approach by utilizing a study library with qualitative in manner. The result of the study revealed that there are three functions of the myth of Kalumpang in protecting the forest and its biodiversity, they myths have a legal function that can control the pattern of human actions in safeguarding nature so as not to damage the living order and environment; ii) myths can be used to preserve nature such as rivers, natural environment, and forests; iii) Indigenous peoples need to have freedom in carrying out the customary law that they believe in. Through this way, they uphold their cultural ideology in nature conservation.
Forest conversion into cacao agroforestry and cacao plantation change the diversity of arbuscular mycorrhizal fungi
Authors: Edy N , Zakaria E K , Lakani I , Hasriyanti  
Published: May 2019

AbstractArbuscular mycorrhizal fungi (AMF), a plant root-fungus association, has been studied widely across different ecosystems. However, little information provided in tropical land use systems. Here, we studied the diversity of AMF in the forest, cacao agroforestry, and cacao plantation. A preliminary survey was done to estimate the AMF richness and diversity. This study reveals an interesting fundamental finding where AMF richness and diversity were significantly higher in the plantation compared to the natural ecosystem. AMF communities were significantly affected mixed vegetation in the forest and became a generalist in an agroecosystem of the cocoa plantation. Presented results indicate that AMF diversity and community structure are influenced by vegetation and ecological conditions.
Progeny Test on Plant Growth Of 2-Year-Old Jabon Merah (Anthocephalus macrophyllus Roxb. Havil.) in Gowa, South Sulawesi, Indonesia :Preeliminary Study
Authors: A’ida N , Muhlis  , Larekeng S H , Arsyad M A , Putra R P , Musriati  , Restu M 
Published: May 2019

Abstract
Jabon Merah (Anthocephalus macrophyllus Roxb. Havil) is a fast growing local species and has bright economic and market prospects. However, the cultivation is unable to accelerate the productivity of this species. One of the breeding strategies to overcome this problem is to establish Seedling Seed Orchard of progeny test were later converted into seed orchard after one up to several selective thinning. This research was aimed to study the growth of Jabon merahs’ families from ten seed zonations in Sulawesi. It was conducted in a Randomized completely block design (RCBD) consisted of 108 families, four treeplots, and seven blocks with planting spacing of 4x3 meters. The measurement was performed at 24 month-old trees, i.e., tree height and diameter. Percentage of the living tree after two years based on progeny test was 69% with 6.1 m of mean height and 7.8 cm of mean diameter at chest height. Heritability of family for height and diameter at chest height were 0.2337 and 0.1873, respectively. Correlation between genetic and tree height and diameter traits was 0.9121.
Habitat Characteristics and Population of cave-dwelling bats in Mara Kallang Cave of Maros-Pangkep Karst Area of South Sulawesi
Authors: Maulany R I , Wolor F S , Nasri N , Achmad A 
Published: May 2019

Abstract
The cave is one of the important habitats for bats in particular Microchiropterans which provides not only protection but also a shelter for breeding, hibernation, and other events. The characteristics of the cave are crucial for habitat selection. An extensive limestone ecosystem found in the four regencies of South Sulawesi (Indonesia) including Maros-Pangkep karst area has been utilized as the main habitats of cave-dwelling bats. One of the cave inhabited by bats is Mara Kallang Cave. This research aims to examine the physical and environmental characteristics of Mara Kallang Cave. Cave-dwelling bat species diversity and population were also assessed. The direct measurement was carried out to quantify the physical and environmental characteristics of the cave. Ibutton data loggers were employed to record data on temperatures and humidity was measured by using thermohygrometer. Several bat individuals were captured and identified by using a mist net trapping method. Roost locations of different bat species inside the cave were also mapped. A number of individuals per species were also recorded by direct counting and re-confirmed with the photographic count. There were 3 species of cave-dwelling bats inhabited Mara Kallang Cave: Hipposideros cervinus, Rhinolophus cf euryotis and Rhinolophus cf arcuatus roosting in station 4 of the cave with the width of 364.9 m2. The average temperature of the roosting site was 23.31°C with the average humidity of 98%. From the three species found in the cave, Rhinolophus cf euryotis had the largest number of individuals with an average of 386 individuals followed by Rhinolophus cf arcuatus with the average individuals of 304. The least colony size was Hipposideros cervinus with a total of 188 individuals on average.