bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resistance training alone or combined with leucine supplementation improves the serum lipid profile of diabetic rats, whereas leucine alone does not
Authors: Martins Carlos Eduardo C. , de Sousa Lima Vanessa B. , Ribeiro Henrique Quintas T. , Tirapegui Julio 
Published: August 2018

Abstract

Objectives. Diabetes mellitus is associated with dyslipidemia, which contributes to a higher risk of thrombosis, atherosclerosis and cardiovascular disease. This study evaluated the effects of leucine and resistance training on the serum lipid profile in rats with streptozotocin-induced diabetes for 8 weeks.

Methods. Wistar rats with neonatal streptozotocin-induced diabetes were treated with leucine supplementation (5%) and/or resistance training (3 days per week) for 8 weeks, and divided in DL (diabetic and leucine), DT (diabetic and resistance training group) and DLT (diabetic, leucine and resistance training) groups. Others 2 groups of animals received isonitrogen AIN-93M diet that was defined as a control diet: group D (diabetic untreated) and group C (non-diabetic).

Results. The decrease in serum total cholesterol and increase in high-density lipoprotein cholesterol (HDL-C) was observed in the resistance training-induced diabetic rats when compared with diabetic rats. There was no change in serum lipid profile in leucine-supplemented diabetic rats and no synergistic effect of leucine and resistance training. The fasting glucose levels were reduced in all animals treated compared to D group.

Conclusion. The diabetic trained rats demonstrate a protective effect of resistance training on the serum lipid profile.
Administration of ghrelin associated with decreased expression of matrix metalloproteinase-9 following normobaric systemic hypoxia in the brain
Authors: Mohaddes Gisou , Babri Shirin , Hossienzadeh Fezzeh 
Published: August 2018

Abstract

Objective. According to our previous studies, ghrelin protects blood brain barrier (BBB) integrity and it attenuates hypoxia-induced brain edema in the hypoxic conditions. However, the underlying mechanisms remain poorly understood. Several studies suggest a role for matrix metal-loproteinase-9 (MMP9) in the BBB disruption and cerebral edema formation. The present study was conducted to determine the effect of ghrelin on MMP9 protein expression in the model of acute and chronic systemic hypoxia.

Methods. Adult male Wistar rats were divided into acute or chronic controls, acute or chronic hypoxia and ghrelin-treated acute or chronic hypoxia groups. The hypoxic groups were kept in the hypoxic chamber (10–11% O2) for two (acute) or ten days (chronic). Effect of ghrelin on MMP9 protein expression was assessed using immunoblotting.

Results. Our results showed that acute and chronic systemic hypoxia increased the MMP9 protein expression in the brain (p<0.001). Treatment with ghrelin significantly attenuated this expression in the cerebral hypoxia (p<0.05).

Conclusion. Our results demonstrate that the neuroprotective effects of ghrelin may be mediated, in part, by decreasing in MMP9 production in the hypoxic brain.
TATHWîR MÂDAH TA'LîM AL-BALÂGHAH Fî DHAU AL-KHARÂITH AL-DZIHNIYAH AL-ILIKTRÛNIYAH WA WASÂIL AL-TAWÂSHUL AL-IJTIMÂ'I
Authors: Nurcholis Ahmad 
Published: August 2018

The researcher’s observation has shown that in many education institutions including those at higher education, Balaghah Instructional Material and its Strategies seem to be monotonous and traditional (based on Behaviorism theory), with which students tend to be passive in their teaching and learning activities. This research was then aimed at both developing model of teaching Balaghah using e-mind mapping and social media, and knowing the effectiveness of this teaching model towards the learning competence of students of Arabic Education Department of State Islamic Institute of Tulungagung. The design of this research was a modified model of Borg’s and Gall’s Research & Development (R&D) which consists of nine (9) stages. The finding of this research was developing Balaghah instructional material using e-mind map and social media which was focused on student-centered, informative, explorative, implementative and cooperative activities, increased the students’ competence of learning Balaghah.
The Reconstruction of Energy Management Law Based on Indonesia Legal System
Authors: Sulaiman Sulaiman , Firmansyah Ade Arif 
Published: August 2018

Two things become an important part of studies in Indonesian law related to energy management. The first, related to the management of natural resources. Second, the energy sector is also related to other sectors, that is forestry, water resources, marine and fisheries, agriculture and plantations, as well as land. Ideally, all of the energy management law must reflect the state ideology, as natural resources energy must be managed for the greater prosperity of the people. Energy should not be administered arbitrarily because, in addition to the utilization, the existence of natural resources should not be separated from the philosophical orientation of Indonesian legislation, Pancasila, and The 1945 Constitution. However, the reality of energy legislation indicates of the authority competes between sectors and alignments to society which is not optimal. It is due to the legal nature of the energy sector which is liberal and still-exploitation oriented and pro-capitalist. By using a socio-legal approach, this paper describes the reconstruction of law-oriented to the Indonesian legal system in energy management based on Pancasila and the 1945 Constitution as the foundation and soul of the energy sector law. Keywords: Reconstruction of Law, Energy Management, the Indonesian Legal System.
¡Las tecnologías inalámbricas RFID y la privacidad humana!
Authors: Ortegón Bolívar Jairo Augusto 
Published: August 2018

Dentro de las diferentes invenciones basadas en tecnologías inalámbricas, el teléfono móvil pertenece a la categoría de las tecnologías convergentes, así mismo ha ampliado nuestro espacio personal al tamaño del planeta, luego ha logrado realmente la globalidad, así solamente lo utilicemos para llamar nuestros amigos. Hasta allí, todo parece bajo control sin embargo cuando la tecnología se encuentra expedita para controlar nuestra vida privada, los alcances de las tecnologías por refinadas y prácticas que sean, debemos de repensar su utilización.
La tecnología RFID, la cual permitirá un estrecho contacto o interconectividad con todo a nuestro alrededor y que ya está en práctica en otros países y se está extendiendo al nuestro rápidamente conlleva a que realmente pensemos, cuál sería el manejo ético de la misma. Si bien es cierto que surgió como una alternativa para sustituir etiquetas y códigos de barras en muchos productos de consumo masivo, quizá no parezca muy importante, pero está expandiendo la esfera de datos de nuestra personalidad digital y nos hará más vulnerables a la violación de nuestra privacidad y no existirá ningún lugar en donde no seamos localizables.
La calidad del software y el futuro de los desarrollos colombianos
Authors: Bolívar Figueroa Andrés Fernando 
Published: August 2018

El término ”calidad del software” cada vez se está haciendo más popular en nuestroterritorio, pero raras veces se comprende en su totalidad. Que las empresas quedesarrollan software en Colombia estén más pendientes no quiere decir que se satisfagan completamente los requisitos de calidad en la producción de un software. No obstante no pretendo mostrar aquí un compendio de las métricas empleadas para medir la calidad de un desarrollo de software, sino ir más allá de las ”nociones” y conceptos, es decir ver el significado de calidad como algo más que mediciones, es tratar de mostrar de una manera simple que no sólo es un aspecto más de la ingeniería del software, sino que conlleva a responsabilidades mas internas por parte del desarrollador.
Perencanaan strategis sistem informasi menggunakan Enterprise Architecture Planning pada PT. Karya Cipta Buana Sentosa Maumere
Authors: Robo Salahudin , Trisno Trisno , Sunardi Sunardi , Santosa Santosa 
Published: August 2018

Teknologi informasi semakin lama semakin maju dan setiap saat selalu ada perkembangannya yang berpengaruh terhadap berbagai aspek kehidupan. Salah satu diantaranya adalah aspek perekonomian yang berdampak positif bagi perusahaan. Oleh karena itu, setiap perusahaan berusaha untuk menerapkan teknologi informasi dengan tujuan meningkatkan efektifitas dalam proses bisnis, agar perusahan mampu memberikan nilai tambah yaitu berupa keunggulan dalam persaingan bisnis. Enterprise Architecture Planning (EAP) merupakan suatu metode pendekatan dalam perencanaan kualitas data yang berorientasi pada kebutuhan bisnis, perencanaan ini terdiri dari arsitektur data, aplikasi dan infrastruktur teknologi. Tujuan dari penelitian ini untuk menghasilkan proses bisnis perusahaan agar berjalan lebih efektif. Pemodelan bisnis yang digunakan pada penelitian menggunakan analisis value chain. Penggunaan value chain untuk mengetahui jenis-jenis kegiatan serta aktifitas yang ada dalam perusahaan, usulan atau rekomendasi sistem informasi tersebut ditunjukan untuk manager perusahaan terkait sesuai dengan visinya. Hasil dari penelitian ini untuk meningkatkan penyelarasan bisnis dan teknologi informasi pada perusahaan. Information technology is getting more advanced and always have a developing affects to various aspects of life. One of them is the aspect of economy that positively impacts the company. As the results, each company attempts to apply the information technology to improve the effectiveness in the business processing, so that company can give the added value such as the predominance in business competition. Enterprise Architecture Planning or EAP is a method of data quality planning approach that is oriented to business needs consisting of data architecture, application and technology infrastructure. The purpose of this study is to produce business processes of the company to run it more effectively. Business modeling that applied in this research is value chain analysis. The used of value chain is to know the type of activities that exist within the company. The proposed information system is addressed to the manager of related company in accordance with its vision.
Comparison of stand structure in managed and virgin european beech forests in Serbia
Authors: Matović Bratislav , STJEPANOVIĆ Stefan , Kneginjić Igor , Stojanović Dejan , Kisin Bratislav , Koprivica Miloš 
Published: August 2018

U radu se prikazuju rezultati usporedbe strukturnih i proizvodnih karakteristika bukovih sastojina gospodarskog i prašumskog tipa u Srbiji. Istraživano je pet sastojina gospodarskog i tri sastojine prašumskog tipa. Cilj ovog istraži­va­nja bio je utvrditi utjecaj prethodnog gospodarenja šumama na strukturnu raznolikost i proizvodne osobine visokih bukovih šuma u Srbiji. Istraživane sastojine nalaze se u planinskom rasponu od 400 do 1200 metara nadmorske visine u područjima gdje se nalaze najproduktivnije bukove šume u Srbiji (slika 1 i tablica 1). Strukturne karakteristike uspore­đe­ne su pomoću sljedećih parametara: visinske krivulje, debljinska struktura, Gini indeks, koeficijent varijacije, koeficijent vitkosti i maksimalne dimenzije dubećih živih i mrtvih stabla. Sastojinsku gustoću i produktivne osobine proučavane su pomoću sljedećih procijenenih taksacijskih elemenata: broj stabala, temeljnica, volumen, biomasa, zaliha ugljika, srednji promjer po temeljnici, Lorajeva srednja visina i volumen mrtvog drveta. Najveće razlike pronađene su u dimenzijama najvećih stabala u bukovim sasatojinama gospodarskog i prašumskog tipa (tablica 4). Određene razlike pro­na­đene su u obliku visinskih krivulja i debljinskoj strukturi, i vrijednostima koeficijenta vitkosti (slike 2, 3, 4 i 5, i tablica 3). Međutim, Ginijev indeks i koeficijent varijacije pokazuju da su bukove sastojine gospodarskog tipa u Srbiji u velikoj mjeri sačuvale iskonsku strukturnu raznolikost (tablica 2 i slika 6). Razlike u prosječnim vrijednostima taksacijskih elemenata sastojina gospodarskog tipa visokih bukovih šumama u Srbiji u odnosu na sastojine prašumskog tipa su statistički značajne, što nam govori da je prethodno gospodarenje imalo značajan utjecaj na promjene u proizvodnim karakteristikama ovih šuma u Srbiji (tablica 5).
Gota: uma revisão da literatura.
Authors: Heckler Adriane Maris , Wust Bruna Uhmann , Libardoni Karine Santos de Bona , Oliveira Tiago Bittencourt de 
Published: August 2018

<p>A Gota ou também chamada de artrite gotosa é uma artropatia inflamatória desencadeada pelo excesso de ácido úrico que acaba se depositando, na forma de cristal de urato monossódico, na articulação. O ácido úrico é o produto final do metabolismo das purinas, que deve dissolver-se no sangue e ser eliminado através da urina. Quantidades excessivas de acido úrico podem surgir devido a erros inatos do metabolismo das purinas seja pela superprodução e/ou insuficiência na excreção renal de ácido úrico ou pode estar relacionado a condições ou enfermidades que elevam seus níveis séricos. O presente estudo baseou-se numa revisão da literatura que teve como objetivo salientar aspectos recentes da gota relacionados a patogenia, além de características clínicas, diagnóstico, prevenção e tratamento. Para a realização desta revisão, foram selecionados artigos científicos publicados em bancos de dados. Foram utilizados artigos publicados nos últimos 15 anos, nos idiomas português, espanhol e inglês. A Gota pode ser dividida em quatro fases: hiperuricemia assintomática, crise aguda, períodos intercríticos e gota crônica que podem evoluir para urolitíase e nefropatia úrica. A gravidade da doença é proporcional à frequência das crises agudas e a repetição desses quadros indica progressão do processo patológico. </p>
Uso de vírus adeno-associado: um avanço na terapia gênica
Authors: Anjos Colombo Gabriela , Lunkes de Melo Gabrielly , Matter Letícia Beatriz 
Published: August 2018

<p><strong>Resumo</strong></p><p>A terapia gênica utiliza técnicas de engenharia genética para interferir na origem de uma doença. Nesta técnica introduz-se uma sequência de DNA codificante nas células do paciente como tratamento para a correção de um problema recorrente devido a um gene mutado. O uso de vetores virais recombinantes para introduzir o gene correto no indivíduo tem se mostrado bastante desafiador e promissor. Este artigo tem como objetivo apresentar de forma atualizada os conceitos básicos e as perspectivas da terapia gênica para doenças as doenças: fibrose cística, artrite reumatoide, hemofilia e dislipidemia (deficiência da lipoproteína lipase) utilizando o vírus adeno-associado (VAA) como vetor doador do novo gene. Os avanços obtidos no emprego desta técnica, como método de tratamento, podem contribuir largamente para a otimização da terapêutica e, consequentemente, melhorar a qualidade de vida de pacientes portadores de diferentes doenças incuráveis. Neste sentido, os VAA têm se mostrado tecnologicamente versáteis, seguros e efetivos veículos no procedimento.</p><p> </p><p><strong>Palavras-chave</strong>: terapia gênica, vírus adeno-associado, fibrose cística, artrite reumatóide, hemofilia, LPLD. </p>
Regulación de las profesiones:¿Estado o mercado?. El entorno normativo para el diseño y ejecución de una política pública de las profesiones en Chile.
Authors: León José Julio , Peña Carlos 
Published: August 2018

This paper analyzes the suitability of strengthening the regulatory framework andÂ public policies in the setting of the relations between citizens and professionals whoÂ graduate from officially recognized higher education centers. In the labor market andÂ in exercising their profession, citizens themselves are affected by asymmetries inÂ information about the ideal skills required by individuals who hold a given degree orÂ university title. This situation has been intensified by the increasing number of higherÂ education centers, rising enrolment figures at this level of education, the variety of degrees offered and,ultimately, the statute of total autonomy granted to these organizations. A review of the Chilean legalÂ framework and a comparison with others appears to indicate that State action can be enhanced in termsof regulating the supply of professional degrees.
Ampliando la mirada. Hacia un nuevo enfoque para la regulación de la oferta de carreras.
Authors: Vásquez Alberto , Zamorano Gastón 
Published: August 2018

Regulating the supply of degrees offered by Universities in the process of accreditationÂ should be no different from the one for higher education as a whole. In the selfregulationÂ process tha each institution needs to have in place as well as in theÂ regulation exercised by external agencies, new criteria and approaches need to beÂ included: a) to see to it that the overall supply of degrees offered maintain an adequate levelÂ of quality and appropriateness, not only in terms of creating new programs; b) to further developcurrent market approaches by including the views of all the stakeholders in the system, ensuringÂ minimum levels of public information on the available supply c) to supplement current criteria byÂ changing the focus of analysis from university degrees to academic projects that are part of theirrespective institutional frameworks, on the one hand and, on the other hand, by changing the perspectiveÂ of a "career marketâ€ to a society-based outlook so as to include all social actors and the major issuesÂ for the country; d) to address the new challenges faced by higher education which imply making theÂ university system a global one, bringing in information technology systems and moving toward lifelongÂ education methods.
Formación continua y a distancia: una visión a partir de la experiencia.
Authors: Oteíza Fidel , Silva Juan 
Published: August 2018

Distance Education is a teaching method that, from the beginning, has been linkedÂ to individuals who need to acquire knowledge but who, for different reasons, do notÂ have access to class-room education. At present, thanks to the progress in informationÂ technology and the growing need for access to ongoing knowledge, the potential of thisÂ teaching method has been enhanced. The educational impact of distance education hasÂ yet to be seen. There are several experiences but the data available is scarce andÂ therefore it is difficult to determine, in quantitative terms, the real extent of this typeÂ of education. Conversely, it is evident that centers offering distance courses haveÂ increased all over the world in number and diversity;moreover, the quantity ofÂ students interested in this type of education is growing increasingly.
La demanda de profesionales universitarios en el contexto nacional: una visión desde la empresa.
Authors: Froemel Juan Enrique 
Published: August 2018

The article addresses the issue of the demand for professionals with university graduate degrees in Chile viewing the question primarily from the standpoint of companies. The paper begins with a discussion on the possibility of measuring demand, its appropriateness and legitimacy. It also provides background data on the influence that some international trends have on employment, and the distinctive features of professionals. It then goes on to analyze the roles played by undergraduate and graduate studies in the training of professionals, and it reviews the types and concepts that underlie such training. The article examines the most outstanding features of Chilean professionals for the future, and ends with a brief reflection on the attitude of Chilean universities vis-Á -vis the demand for professionals.
La acreditación en la generación de información sobre la calidad de la educación superior.
Authors: Rodríguez-Ponce Emilio , Fleet Nicolás , Delgado Milagros 
Published: August 2018

This essay discusses limitations of higher education system to produce information about its own quality. These emerge from an imbalance between the prevailing interests in the systems diverse coordination poles (institutions,Â market and State). This article proposes the accreditation process as a counteracting mechanism and redefines it from its capacity to produce information about higher education quality which leads to strengthen regulations for the whole system and improve its results. Hence, regulation and information are not replaceable strategies and their mutual empowerment represents a development for the higher education system.Â
¿Son las habilidades matemáticas un asunto de Género? Los estereotipos de género acerca de las matemáticas en niños y niñas de Kínder, sus familias y educadoras.
Authors: Del Río María Francisca , Strasser Katherine , Susperreguy María Inés 
Published: August 2018

National as well as international standardized assessments reveal that Chile has a large genderÂ gap in math achievement that favors male students. Some theories propose that at least part of this gap can be explained by the effects of gender stereotypes that refer to abilities in math.In the present study, we examine the implicit and explicit gender stereotypes related to math of kindergarten children, their mothers, fathers and teachers in Santiago, Chile. The participantsÂ were 180 kindergarteners from mid-low and high SES (87 girls and 93 boys, from 19 classrooms),Â their parents and classroom teachers, from the urban area of Santiago, Chile. Participants were assessed on explicit and implicit gender stereotypes on math ability. Results show that, on average, both adults and children hold a stereotype that associates math to the male gender. In the case of children, the results of the implicit assessments reveal that all of the boys and mid-low-SES girls relate math to the male gender, while high-SES girls do not associate math to any gender. These findings suggest that math and gender stereotypes could help explain part of the math gender gap present in Chile, and thus suggest opportunities for early interventions and public policies that seek to offer children equal learning opportunities, particularly for girls and mothers from mid-low SES, who most intensely present this stereotype.Â
Usos de datos y mejora escolar: Una aproximación a los sentidos y prácticas educativas subyacentes a los procesos de toma de decisiones.
Authors: Parra Victoria , Matus Gladys 
Published: August 2018

The implementation of the National System of Quality Assurance in Education (SNAC) in Chile, fosters a relationship between ministerial agencies and schools characterized by the production of external evaluations and data to guide school improvement. The present article contributes information on the challenges public schools face, in response to the first implementation phase of SNAC performed by the Quality Assurance Agency (ACE). To this end, and based on a review Â of international literature, the authors propose a conceptual definition of data highlighting a reflexive approach. This definition was employed to study four municipal schools located in the Metropolitan Region. The main findings of the study illustrate the strategies and processes of data analysis/use, performed by the schools, along with identifying the factors that influence these actions. The findings further underscore the strong influence of accountability on how the school actors conceptualize the value and use of data provided by SNAC, which influences how this data is used to inform school decision-making. The article suggests guidelines for education policy that would promote a contextualized, timely, and systemic use of data in municipal schools.