bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anomalocardia brasiliana shellfish shells as a novel and ecofriendly adsorbent of Nylosan Brilliant Blue acid dye
Authors: de Paiva Tarsila Maíra Nogueira , Fraga Tiago José Marques , Sales Davyson Cesar S. , Carvalho Marilda Nascimento , da Motta Sobrinho Maurício Alves 
Published: October 2018

Abstract
Malacoculture waste (Anomalocardia brasiliana) shellfish shells (ABSS) were evaluated as adsorbents of Nylosan Brilliant Blue (NBB) acid dye. The ABSS were thermally activated at 1,000 °C for 10 h and then characterized by Fourier-transform infrared spectroscopy, analysis of specific surface area (BET), X-ray diffraction (XRD), and scanning electron microscopy. Point of zero charge (PZC) analysis of ABSS verified pHPZC 13.0. The study of kinetics showed that the pseudo-second-order model fit the experimental data best and the system reached equilibrium within 5 min. Adsorption isotherms followed the Langmuir–Freundlich isotherm and ABSS reached an outstanding maximum adsorption capacity of 405 mg·g−1 under the following optimum conditions: pH 12.4, 303 K, 450 rpm, 2.0 g of adsorbent, and 150 μm average particle size. These conditions were obtained after a previous statistical analysis of the variables. Enthalpy and Gibbs energy obtained in the thermodynamics experiments were −23.79 kJ·mol−1 and −4.07 kJ·mol−1, respectively. These parameters confirm that the process is exothermic, spontaneous, and indicative of the physical nature of the adsorption. The adsorption of NBB onto ABSS tended to be more favorable at a lower temperature. Low value of enthalpy suggested that weak binding forces, such as electrostatic interactions, govern the sorption mechanism. ABSS high availability in the environment, its low toxicity and high efficiency make it a promising ecofriendly adsorbent of textile dyes.
Efficient capture of phosphate from aqueous solution using acid activated akadama clay and mechanisms analysis
Authors: Wang Ying , He Hui , Zhang Nan , Shimizu Kazuya , Lei Zhongfang , Zhang Zhenya 
Published: October 2018

Abstract
In this study, akadama clay, a kind of volcano ash, was activated with sulfuric acid and then evaluated for the adsorption of phosphate from aqueous solution via batch experiments. The effects of adsorbent dose, initial pH and coexisting anions on phosphate removal by natural akadama clay and acid-activated akadama clay were investigated. Based on the pH effect, the modified adsorbent could efficiently capture phosphate over a wider pH range of 3.00–6.00 than natural akadama clay. Competitive anions showed negative effects on the phosphate adsorption, especially citrate and carbonate. The adsorption process followed the pseudo-second-order kinetic equation and the intra-particle diffusion. Langmuir isotherm model was found to fit the data better than Freundlich model, and the maximum adsorption capacities of phosphate onto the natural akadama clay and acid-activated akadama clay were 5.88 and 9.19 mg/g, respectively. Furthermore, thermodynamic studies confirmed that the adsorption of acid-activated akadama clay was a spontaneous process. The mechanisms of phosphate adsorption on the clay could be ascribed to electrostatic attraction and ligand exchange. These results suggest that after modification, acid-activated akadama clay could be used as a promising adsorbent for phosphate removal from wastewater in real application and then further used as fertilizers.
Preparation of Cationic Lipid-coated Ultrasound Contrast Agents and Noninvasive Gene Transfection Via Ultrasound-targeted Microbubble Destruction
Authors: Yang Feng , Li Yue , Liufu Chun , Wang Yi , Chen ZhiYi 
Published: October 2018

Purpose: Ultrasound contrast agents involving a therapeutic drug applied during enhanced imaging
can be used for targeted therapy. The preparation of contrast agents is a precondition and basis for the use of
multifunctional contrast agents in molecular imaging.

Methods:
This study uses thin-film hydration-mechanical vibration to carry out the preliminary preparation of a
cationic contrast agent (CCA); characterizes the particle diameter, potential, distribution, and concentration of the
agents; and optimizes the factors affecting the preparation of the agents.

Results:
This study found that thin-film hydration-mechanical vibration methods offer a better preparation effectiveness
and achieve smaller particle diameters and more even distributions, as well as give better imaging performance.
Different concentrations of CCA and plasmid and different gene transfection methods can produce
different degrees of sonoporation to achieve optimal transfection efficiency. Ultrasound parameters have a great
influence on transfection efficiency and plasmid integrity. A previous study confirmed that the ultrasound parameters
of 1 MHz, 1 W/cm2, a duty cycle controller (DC) of 20%, and irradiation for 1 min can well deliver
genes to tumor cells, with little impact on cell survival.

Conclusion:
Our findings indicate that ultrasound-targeted microbubble destruction (UTMD)-mediated CCA
destruction facilitates gene transfection and may represent an effective gene delivery method for cervical cancer
therapy.
In Silico Design of Fusion Toxin DT389GCSF and a Comparative Study
Authors: Siahmazgi Maryam G. , Khalili Mohammad A.N. , Ahmadpour Fathollah , Khodadadi Sirus , Zeinoddini Mehdi 
Published: October 2018

Background:Chemotherapy and radiotherapy have negative effects on normal tissues and they are very expensive and lengthy treatments. These disadvantages have recently attracted researchers to the new methods that specifically affect cancerous tissues and have lower damage to normal tissues. One of these methods is the use of intelligent recombinant fusion toxin. The fusion toxin DTGCSF, which consists of linked Diphtheria Toxin (DT) and Granulocyte Colony Stimulate Factor (GCSF), was first studied by Chadwick et al. in 1993 where HATPL linker provided the linking sequence between GCSF and the 486 amino acid sequences of DT.Methods:In this study, the fusion toxin DT389GCSF is evaluated for functional structure in silico. With the idea of the commercial fusion toxin of Ontak, the DT in this fusion protein is designed incomplete for 389 amino acids and is linked to the beginning of the GCSF cytokine via the SG4SM linker (DT389GCSF). The affinity of the DT389GCSF as a ligand with GCSF-R as receptor was compared with DT486GCSF as a ligand with GCSF-R as receptor. Both DT486GCSF and its receptor GCSF-R have been modeled by Easy Modeler2 software. Our fusion protein (DT389GCSF) and GCSF-R are modeled through Modeller software; all of the structures were confirmed by server MDWEB and VMD software. Then, the interaction studies between two proteins are done using protein-protein docking (HADDOCK 2.2 web server) for both the fusion protein in this study and DT486GCSF.Results:The HADDOCK results demonstrate that the interaction of DT389GCSF with GCSF-R is very different and has a more powerful interaction than DT486GCSF with GCSF-R.Conclusion:HADDOCK web server is operative tools for evaluation of protein–protein interactions, therefore, in silico study of DT389GCSF will help with studying the function and the structure of these molecules. Moreover, DT389GCSF may have important new therapeutic applications.
Computational Study on the Role of γ-Synuclein in Inhibiting the α-Synuclein Aggregation
Authors: Sanjeev Airy , Mattaparthi Venkata S.K. 
Published: October 2018

Background:
α-Synuclein (αS) is the precursor protein present in Lewy Bodies that helps
in the formation of highly ordered amyloid fibrils that is associated with the occurrence of Parkinson’s
disease, a neuro-degenerative disorder. Many reports have now been focused on finding the
probable targets to weaken this debilitating disease. Recently γ-synuclein (γS), a presynaptic protein,
was highlighted to inhibit the aggregation propensity of αS both in vivo and in vitro. However the nature,
location and specificity of molecular interactions existing between the αS and γS is not known
in spite of the potential importance of γS as an inhibitor of αS.

Objective:
To understand the inhibition of αS aggregation by γS at the molecular level.

Methods:
Umbrella sampling method was used along with molecular dynamics simulation to investigate
the conformational dynamics, degree of association and molecular interaction between the
monomeric units in the αS/γS hetero-dimer.

Results and Discussion:
The dissociation energy barrier for αS/γS hetero-dimer was found to be higher than αS/αS homo-dimer. αS can therefore readily form a hetero-dimer by combining with γS than forming a homo-dimer. We also observed strong transient interactions involving hydrogen bonds, salt-bridges and non-bonded contacts between the monomeric units in αS/γS hetero-dimer.

Conclusion:
Our findings suggest that γS may inhibit the aggregation propensity of αS.
Diphtheria Immunity in Australia: Should we be Concerned?
Authors: Lu Xinting , Quinn Helen E. , Menzies Rob I. , Hueston Linda , Gilbert Lyn , McIntyre Peter B. 
Published: October 2018

Objective:
We report the results of the 2007 national serological survey of immunity
to diphtheria in Australia to assess the impact of recent schedule changes on diphtheria immunity,
and the adequacy of current policy in the context of increased international travel of people and
pathogens.

Methods:
Residual sera (n =1656) collected opportunistically from Australian laboratories in 2007
were tested for diphtheria antibody levels using an enzyme immunoassay, with the protective
threshold defined as ≥0.1 IU/mL. About 40% of adults aged ≥30 years are susceptible to diphtheria;
following the removal of the 18-month booster and its replacement with a dose in adolescence
offered through school-based dTpa vaccination program, 59% of children aged 3 years were susceptible
to diphtheria, whilst adolescents demonstrated improved immunity.

Results:
There is no apparent boosting of diphtheria immunity from meningococcal group C conjugate
(MCC) or seven-valent pneumococcal conjugate (7vPCV) vaccines in relevant age groups.

Conclusion:
Australians who travel to diphtheria-endemic areas should be up-to-date with their
vaccinations. Close monitoring of population immunity levels against diphtheria remains important
to ensure that immunity does not decline to a level where wide-spread transmission would be
possible.V
Pengaruh jarak transportasi terhadap biokimia darah ayam broiler
Authors: Purwadi Bagus Aji , Sarjana Teysar Adi , Murwani Retno 
Published: October 2018

The objective of this research is to examine the effect of transportation distance on haemoglobin, hematocrit, erythrocytes, plasmaglucose, triglyceride and cholesterol of broilers. Two hundred and fifty two broilers with an average body weight of 2.0 ± 0.08 kg were dividedinto transportation distance namely T1: 60 km, T2: 120 km, T3: 180 km. The data were analyzed by Anova whenthere was a significant effect Duncan test was conducted. Longer transportation distance significantly decreased plasma hemoglobin, hematocrit and triglyceride (P≤0,05), while erythrocytes, glucose and cholesterol level were not significantly affected (P&gt;0.05).The conclusion of this study is broiler transport at a distance of 120 km has reduced hemoglobin, hematocrit, and plasma triglyceride levels.
Degradasi komponen serat serbuk gergaji hasil biokonversi jamur tiram putih (Pleurotus ostreatus) dengan level urea berbeda
Authors: Krishaditersanto Rip 
Published: October 2018

This study aims to determine the effect of urea supplementation on substrate to the change percentage content of crude fibre component of sawdust as the yield of bioconversion by <em>Pleurotus ostreatus</em> with 40 days incubation period. The design used was Complete Random Design (CRD) with 4 levels of urea that is P<sub>0</sub> = sawdust substrate + 0% urea; P<sub>1</sub> = sawdust substrate + 0.5% urea; P<sub>2</sub> = sawdust substrate + 1% urea; P<sub>3</sub> = sawdust substrate + 1.5% urea;and P<sub>4</sub> = sawdust substrate + 2% urea, with 3 replicates at each treatment. The parameters observed were the change percentage content of Neutral Detergent Fibre (NDF), Acid Detergent Fibre (ADF), hemicellulose, cellulose, and lignin. From the observation on the growth of myceliumseen on P2 is the best. The percentage decrease in the content of all fiber components in P2 is the highest. Analyzed data using analysis of variance, showed that urea supplementation had significant effect (P &lt;0,05) to the change percentage content of Neutral Detergent Fibre (NDF), Acid Detergent Fibre (ADF), hemicellulose, cellulose, and lignin. Bioconversion of sawdust by <em>Pleurotus ostreatus</em> with level of urea supplementation 1% yields the highest of the change percentage content of crude fibre component.
A existência segundo Fernando Pessoa:
Authors: Souza Ricardo Pires de 
Published: October 2018

Este trabalho busca demonstrar o paralelo existente entre as ideias junguianas de si-mesmo, de função religiosa e numinoso e a angústia existencial na escrita de Fernando Pessoa. Dentro desse escopo, um aspecto na obra e vida de Pessoa merece olhar analítico: o enfrentamento do vazio existencial - o medo profundo diante da ideia da morte e da completa ausência de significado intrínseco que o mundo natural apresenta, aí incluído, para o poeta, o mundo social humano onde ele se sente eternamente deslocado. Essa é a motivação maior da sua vida e a marca universal da sua obra: a angústia existencial presente em todas as suas personalidades literárias e heterônimos, principalmente o Pessoa "ele-mesmo" ou ortônimo, resultando na Poesia, tida como valor supremo e imagem de Deus. De fato, terror e fascinação caracterizam toda imagem, ideia ou experiência de Deus, fundamento da função religiosa descrita por Jung em sua teoria do inconsciente, fenômeno que ele chama de numinoso. Na teoria junguiana, essa função é psicologicamente representada pelo arquétipo do Self ou si-mesmo, simultaneamente centro e totalidade da experiência psíquica humana, responsável tanto pela geração quanto pela contenção da angústia existencial que nos acomete quando confrontamos nossos dilemas narrativos fundamentais: vida e morte, existência e não-existência, materialidade e imaterialidade, determinismo e indeterminismo, acaso e finalidade. Assim, o fator Self é o responsável por todos os mitos e religiões desde que começamos a sepultar nossos mortos. Individualmente, no fazer imaginativo pessoano, o Self ocupou o lugar do sagrado sob a forma da Poesia.
Polygamy and Muslim Women in Contemporary Indonesian Literature
Authors: Wajiran Wajiran 
Published: October 2018

This paper will examine the ways in which polygamy is addressed in contemporary Indonesian literature. The literature that will be analysed is that published after the reformation era, whereby new freedoms have encouraged many Muslim writers to raise this controversial issue. This paper will apply feminist theory especially that of the Muslim feminist Amina Wadud. Furthermore, in order to understand the contextuality of the works, a cultural materialist approach is also applied. There are some Indonesian writers who overtly depict polygamy in their literature, such as Habiburrahman El Shirazy and Alfina Dewi. Although they are all Muslims they have different perspectives in presenting the issue of polygamy in their works. These differences reflect Indonesian Islamic society where polygamy is controversial. Some Muslims accept polygamy as Islamic teaching but others do not.
Граничное поведение и задача аналитического продолжения одного класса рядов Дирихле с мультипликативными коэффициентами как целых функций на комплексную плоскость
Authors: Кузнецов В. Н. , Матвеева О. А. 
Published: October 2018

Рассматривается класс рядов Дирихле с мультипликативными коэффициентами, определяющих функции, регулярные в правой полуплоскости комплексной плоскости и допускающие аппроксимацию полиномами Дирихле в критической полосе. Показано, что условие регулярности на мнимой оси позволяет аналитически продолжить такие ряды как целые функции на комплексную плоскость.В основе доказательсва этого факта лежат свойства аппроцксимационных полиномов Дирихле и идеи Римана-Шварца, заложенные в принципе симметрии аналитического продолжения функций комплексного переменного. Указан класс рядов Дирихле, для которых выполняется условие аналитичности на мнимой оси.Нужно отметить, что полученный в работе результат имеет непосредственное отношение к решению известной проблемы обобщенных характеров, поставленной Ю. В. Линником и Н. Г. Чудаковым в 1950м году.Указанный в работе подход в задаче аналитического продолжения рядов Дирихле с числовыми характерами допускает обобщение на ряды Дирихле с характерами числовых полей. Это позвволяет получить аналитическое продолжение не используя функциональное уравнение L-функций Дирихле числовых полей на комплексную плоскость.Отметим также, что изучаемому в работе классу рядов Дирихле принадлежат и ряды Дирихле, коэффициенты которых определяются неглавными обобщенными характерами. Можно показать, что для этих рядов выполняется условие аналитического продолжения. Еще в 1984 году В. Н. Кузнецов показал, что в случае аналитического продолжения таких рядов целым образом на комплексную плоскость с определенным порядком роста модуля, то будет иметь место гипотеза Н. Г. Чудакова о том, что обобщенный характер является характером Дирихле. Но окончательное решение проблемы обобщенных характеров, поставленной в 1950м году Ю. В. Линником и Н. Г. Чудаковым, будет приведено в следующих работах авторов.
О взвешенном числе точек алгебраической сетки
Authors: Рарова Е. М. 
Published: October 2018

Работа посвящена изучению тригонометрических сумм алгебраических сеток с весами, которые играют центральную роль в модификации метода К. К. Фролова, предложенной Н. М. Добровольским в 1984 году. Тригонометрическую сумму алгебраической сетки с весами для вектора ⃗m = ⃗0, естественно, назвать взвешенным числом точек алгебраической сетки.Во введении данной работы предложено обоснование актуальности темы исследования, даются необходимые определения и факты из современной теории метода К. К. Фролова, доказывается важная теорема о разложении тригонометрической суммы алгебраической сетки с весами в ряд по точкам алгебраической сетки. В разделе «Вспомогательные леммы» приводятся без доказательства необходимые факты из теории весовых функций специального вида, которые играют принципиальную роль в модификации Н. М. Добровольского метода К. К. Фролова.Используя теорему о разложении тригонометрической суммы алгебраической сетки с весами в ряд по точкам алгебраической сетки и лемму о значении тригонометрического интеграла от весовой функции, в работе выводится асимптотическая формула для взвешенного числа точек алгебраической сетки со специальной весовой функцией порядка 2, которая утверждает, что такое число стремится к единице. Аналогично, показано, что при росте детерминанта алгебраической решётки для любого вектора ⃗m ≠ ⃗0, тригонометрическая сумма алгебраических сеток с весами, заданной специальной весовой функцией, стремится к 0.Для простоты изложения в основном тексте статьи рассматривается только случай простейшей весовой функции порядка 2.В заключении сформулированы без доказательства аналогичные утверждения о значениях тригонометрических сумм алгебраических сеток со специальными весовыми функциями порядка r + 1 для произвольного натурального r.А именно, утверждается, что для взвешенного числа точек алгебраической сетки со специальной весовой функцией порядка r справедливо стремление к 1 с остаточным членом порядка s−1 логарифма детерминанта алгебраической решётки, делённого на r + 1 степень детерминанта алгебраической решётки. Аналогичное утверждение справедливо о стремлении к нулю тригонометрической суммы алгебраической сетки с весами, заданной специальной весовой функцией порядка r + 1.
Рассеяние звуковых волн упругим эллипсоидом с неоднородным покрытием в полупространстве с идеальной поверхностью
Authors: Скобельцын С. А. 
Published: October 2018

Представлено решение задачи дифракции плоской звуковой волны на упругом эллипсоиде E с внешним слоисто-неоднородным слоем. Эллипсоид находится в полупространстве, заполненном идеальной жидкостью. Граница полупространства Π является акустически жесткой или акустически мягкой поверхностью.Для решения область, занятая жидкостью, расширена до полного пространства. Введено дополнительное препятствие, являющееся копией E, расположенное зеркально по отношению к плоскости Π. Добавление второй падающей плоской волны обеспечивает выполнение того условия в точках плоскости Π, которое соответствует типу границы полупространства в начальной постановке задачи. Таким образом, задача сводится к задаче о рассеянии двух плоских звуковых волн на двух эллипсоидах в неограниченном пространстве.Решение проводится на основе линейной теории упругости и модели распространения малых возмущений в идеальной жидкости. Во внешней части окружающей среды решение ищется аналитически в форме разложения по сферическим гармоникам и функциям Бесселя. В шаровой области, включающей два эллипсоида и прилегающий слой жидкости, используется метод конечных элементов (МКЭ).Представлены результаты расчета диаграмм направленности рассеянного звукового поля в дальней зоне, которые показывают влияние геометрических и материальных параметров эллипсоида на дифракцию звука.