bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of a crossing suture to correct caudal septal deviations
Authors: Joo Yeon‐Hee , Cho Hyun‐Jin , Jeon Yung Jin , Kim Sang‐Wook 
Published: May 2019

BackgroundSeptoplasty usefully treats patients with nasal obstructions caused by septal deviations. However, correction of a caudal septal deviation remains surgically challenging; no standard procedure is available, although various procedures have been introduced. In this work we propose a simple, safe, and time‐saving technique for patients with caudal septal deviations.MethodsThe medical records of 50 patients with caudal septal deviations who underwent septoplasty using a crossing‐suture technique from October 2016 to October 2018 were retrospectively reviewed. Postoperative nasal obstruction status and patient satisfaction with their surgical outcomes were subjectively evaluated using the Nasal Obstruction Symptom Evaluation (NOSE) score and telephone interview, respectively. Pre‐ and postoperative endoscopic findings were evaluated and postoperative complications developing during follow‐up were recorded.ResultsThe NOSE scores of all patients improved after septoplasty. The mean score fell from 13.46 to 3.97, and this change was significant (p < 0.0001). No complication related to use of the crossing suture was encountered.ConclusionThe crossing‐suture technique is a simple, safe, and useful surgical option for correction of caudal septal deviations.
Specific Generation of Singlet Oxygen through the Russell Mechanism in Hypoxic Tumors and GSH Depletion by Cu‐TCPP Nanosheets for Cancer Therapy
Authors: Wang Chao , Cao Fengjuan , Ruan Yudi , Jia Xiaodan , Zhen Wenyao , Jiang Xiue 
Published: May 2019

AbstractThe generation of singlet oxygen (1O2) during photodynamic therapy is limited by the precise cooperation of light, photosensitizer, and oxygen, and the therapeutic efficiency is restricted by the elevated glutathione (GSH) levels in cancer cells. Herein, we report that an ultrathin two‐dimensional metal–organic framework of Cu‐TCPP nanosheets (TCPP=tetrakis(4‐carboxyphenyl)porphyrin) can selectively generate 1O2 in a tumor microenvironment. This process is based on the peroxidation of the TCPP ligand by acidic H2O2 followed by reduction to peroxyl radicals under the action of the peroxidase‐like nanosheets and Cu2+, and their spontaneous recombination reaction by the Russell mechanism. In addition, the nanosheets can also deplete GSH. Consequently, the Cu‐TCPP nanosheets can selectively destroy tumor cells with high efficiency, constituting an attractive way to overcome current limitations of photodynamic therapy.
Characterization of UV‐curable adhesives containing acrylate monomers and fluorosurfactant and their performance in dye‐sensitized solar cells in long‐term thermal stability tests
Authors: Chiang Tzu Hsuan , Chen Chun Hsiung , Wei Tzu‐Chien 
Published: May 2019

ABSTRACTElectrolytes were injected through holes in dye‐sensitized solar cells (DSSCs), and the holes were subsequently sealed with UV‐curable adhesives containing different types of acrylate monomers and different amounts of fluorosurfactants, which were found to affect the performance of the DSSCs during long‐term stability tests. The efficiency (η) of the DSSCs' conversion of light to electricity is an important parameter. The corrosion potential (Ecorr) toward the liquid electrolyte and the adhesion strength of the UV‐curable adhesives to fluorine‐doped tin oxide (FTO) glass affected the efficiency of DSSCs during long‐term thermal stability tests. The UV‐curable adhesive containing 10.0 wt % of acrylic acid (AA) monomer and 3.0–4.0 wt % of fluorosurfactant, when used to seal DSSC devices, led to the best DSSC performance of η = 4.1% during a 45‐day long‐term thermal stability test. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47948.
Magnetically aligning multilayer graphene to enhance thermal conductivity of silicone rubber composites
Authors: Shi Yangyang , Ma Wenshi , Wu Li , Hu Dechao , Mo Jinpeng , Yang Bo , Zhang Shuanghong , Zhang Zhilin 
Published: May 2019

ABSTRACTThe increasing demand for packaging materials calls for new technologies to achieve excellent thermal conductivity of polymer composites with low content of thermal conductive filler. This article prepared a kind of magnetically functionalized multilayer graphene (Fe3O4@MG) via electrostatic interactions, which efficiently enhanced the thermal conductivity of silicone rubber (SR) composites by the alignment of Fe3O4@MG in an external magnetic field. The morphology and structure of the Fe3O4@MG together with the thermal conductivity of corresponding Fe3O4@MG/SR composites were systematically investigated by SEM, TEM, XRD, elemental mapping, and thermal conductivity tester. The obtained results showed that Fe3O4@MG was induced to form chain‐like bundles in silicone rubber matrix under the applied magnetic field, which enhanced the MG–MG interaction, and formed effective thermal pathways in the alignment direction. Furthermore, as coating mass ratio of Fe3O4@MG increased, the thermal conductivity of randomly oriented Fe3O4@MG/silicone rubber composites (R‐Fe3O4@MG/SR) decreased gradually, whereas the through‐plane thermal conductivity of vertically aligned Fe3O4@MG/silicone rubber composites (V‐Fe3O4@MG/SR) increased even filled with same contents of thermal conductive filler. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47951.
Multiple colic intussusceptions
Authors: Tzedakis Stylianos , Flacs Meredith , Besse Benjamin , Goere Diane 
Published: May 2019

AbstractAdult large bowel intussusception represents a small minority of intestinal intussusceptions. Main causes involve primary or secondary bowel malignancies. Although multiple small intestine intussusceptions have already been reported, simultaneous large bowel intussusceptions have not been described in the literature so far.
Ultrafine particle deposition in a realistic human airway at multiple inhalation scenarios
Authors: Dong Jingliang , Shang Yidan , Tian Lin , Inthavong Kiao , Qiu Dasheng , Tu Jiyuan 
Published: May 2019

AbstractThe scarcity of regional deposition data in distal respiratory airways represents an important challenge for current toxicology and pharmacology research. To bridge this gap, a realistic airway model extending from nasal and oral openings to distal bronchial airways with varying pathway length was built in this study. Transport and deposition characteristics of naturally inhaled ultrafine particles (UFPs) ranging from 1 to 100 nm were numerically investigated, and effects of different inhalation scenarios were considered. To enable intercase particle deposition comparison, an adjusted parameter, unified deposition enhancement factor (UDEF), was proposed for quantifying the localised deposition concentration. Results show that compartment particle deposition peaked around the ultrafine end of the considered size range, and it dropped rapidly with the increase of particle size. Different inhalation modes caused notable deposition changes in the extrathoracic region, while its effects in the TB airway are much less. For UFPs larger than 10 nm, predicted deposition efficiencies in all compartments are all at lowest levels among considered particle size range, implying UFPs ranging from 10 to 100 nm can travel through the whole respiratory airway model and escape to the alveolar region. Furthermore, high enhancement factors were observed at the vicinity of most bifurcation apexes, and more even UDEF distribution was observed from 1‐nm particle cases. While for 100‐nm cases, the deposited particles tend to concentrate at few “hot spots” (areas of high deposition concentration in relation to surrounding surfaces) with greater UDEF in the tracheobronchial airway.
Mono‐/Multinuclear Water Oxidation Catalysts
Authors: Zhang Qiaoqiao , Guan Jingqi 
Published: May 2019

AbstractWater splitting, in which water molecules can be transformed into hydrogen and oxygen, is an appealing energy conversion and transformation strategy to address the environmental and energy crisis. The oxygen evolution reaction (OER) is dynamically slow, which limits energy conversion efficiency during the water‐splitting process and requires high‐efficiency water oxidation catalysts (WOCs) to overcome the OER energy barrier. It is generally accepted that multinuclear WOCs possess superior OER performances, as demonstrated by the CaMn4O5 cluster in photosystem II (PSII), which can catalyze the OER efficiently with a very low overpotential. Inspired by the CaMn4O5 cluster in PSII, some multinuclear WOCs were synthesized that could catalyze water oxidation. In addition, some mononuclear molecular WOCs also show high water oxidation activity. However, it cannot be excluded that the high activity arises from the formation of dimeric species. Recently, some mononuclear heterogeneous WOCs showed a high water oxidation activity, which testified that mononuclear active sites with suitable coordination surroundings could also catalyze water oxidation efficiently. This Review focuses on recent progress in the development of mono‐/multinuclear homo‐ and heterogeneous catalysts for water oxidation. The active sites and possible catalytic mechanisms for water oxidation on the mono‐/multinuclear WOCs are provided.
Solid phase extraction of trace level Ag(I) using Coriolus versicolor immobilized magnetic nanoparticles and its determination by ICP‐OES
Authors: Serkan Yalçın M. 
Published: May 2019

AbstractIn the recent past, biosorbents of biological origin such as bacteria, algae, and fungus have found a specific application in the solid phase extraction as an alternative column packing material. It is feasible to use them in the column after their immobilization onto a convenient support material. In the present work, alternative biosorbent Coriolus versicolor immobilized γ‐Fe2O3 nanoparticles (NPs) were prepared for the preconcentration of trace amounts of Ag(I) in environmental samples. The surface structure of C. versicolor immobilized γ‐Fe2O3 NPs were identified via the Fourier transform infrared spectroscopy, the scanning electron microscope, and the energy dispersive X‐ray. Experimental parameters were investigated. The following elution with 1 mol/L HCl, Ag(I) was measured by an inductively coupled plasma optical emission spectrometer. The limit of detection, limit of quantitation, and preconcentration factor were achieved as 0.0018, 0.0062 ng/ml, and 100, respectively. The biosorption capacity of the biosorbent was found as 31.7 mg/g. In addition, γ‐Fe2O3 NPs without C. versicolor were tested and the results showed that the recovery value of Ag(I) was lower than 25%. The efficiency of the method was tested through recovery measurements of certificated reference materials and high recoveries (≥95%) with low‐relative standard deviation were obtained. Additionally, it was successfully used for the quantification recovery of Ag(I) in spiked environmental samples. © 2019 American Institute of Chemical Engineers Environ Prog, 38:e13151, 2019
Load effects on spatial working memory performance are linked to distributed alpha and beta oscillations
Authors: Proskovec Amy L. , Wiesman Alex I. , Heinrichs‐Graham Elizabeth , Wilson Tony W. 
Published: May 2019

AbstractIncreasing spatial working memory (SWM) load is generally associated with declines in behavioral performance, but the neural correlates of load‐related behavioral effects remain poorly understood. Herein, we examine the alterations in oscillatory activity that accompany such performance changes in 22 healthy adults who performed a two‐ and four‐load SWM task during magnetoencephalography (MEG). All MEG data were transformed into the time‐frequency domain and significant oscillatory responses were imaged separately per load using a beamformer. Whole‐brain correlation maps were computed using the load‐related beamformer difference images and load‐related accuracy effects on the SWM task. The results indicated that load‐related differences in left inferior frontal alpha activity during encoding and maintenance were negatively correlated with load‐related accuracy differences on the SWM task. That is, individuals who had more substantial decreases in prefrontal alpha during high‐relative to low‐load SWM trials tended to have smaller performance decrements on the high‐load condition (i.e., they performed more accurately). The same pattern of neurobehavioral correlations was observed during the maintenance period for right superior temporal alpha activity and right superior parietal beta activity. Importantly, this is the first study to employ a voxel‐wise whole‐brain approach to significantly link load‐related oscillatory differences and load‐related SWM performance differences.
The effect of modified electrospun PCL‐nHA‐nZnO scaffolds on osteogenesis and angiogenesis
Authors: Rahmani Amin , Hashemi‐Najafabadi Sameereh , Eslaminejad Mohamadreza Baghaban , Bagheri Fatemeh , Sayahpour Forough Azam 
Published: May 2019

AbstractLarge bone defects treatment is one of the challenges in current bone tissue engineering approaches. Various strategies have been proposed to address this issue, among which, prevascularization by coculturing of angiogenic and osteogenic cells on the scaffolds can alleviate this problem. In the present study, modified fibrous scaffolds were prepared by electrospinning and subsequent ultrasonication of polycaprolactone (PCL) containing nano‐hydroxyapatite (n‐HA), with/without nano‐zinc oxide (n‐ZnO), and polyethylene oxide [PEO] as a sacrificial agent. The physical, mechanical, and chemical characteristics of the scaffolds were evaluated. The results showed the presence of n‐ZnO, which in turn increased Young's module of the scaffolds from 5.5 ± 0.67 to 6.7 ± 1.77 MPa. Moreover, MTT, SEM, alkaline phosphatase (ALP) activity, chicken embryo chorioallantoic membrane (CAM) assay, and real‐time RT‐PCR were utilized to investigate the biocompatibility, cell adhesion and infiltration, osteoconductivity, angiogenic properties, and expression of osteogenic and angiogenic related genes. ALP assay showed that the highest enzyme activity was noted when the modified scaffolds containing n‐ZnO were seeded with HUVEC:hBMSC at the cell ratio of 1:5. CAM assay showed induction of angiogenesis for the scaffolds containing n‐ZnO. Real‐time RT‐PCR results showed significant upregulation of angiogenic related genes. Thus, the scaffolds containing n‐ZnO may have great potential for osteogenesis and angiogenesis in tissue engineering applications.
Mass spectrometry combined with affinity probes for the identification of CP4 EPSPS in genetically modified soybeans
Authors: Devi Shobha , Chu Pei‐Yu , Wu Bo‐Hung , Ho Yen‐Peng 
Published: May 2019

AbstractSample preparation methods used for genetically modified organisms (GMOs) analysis are often time consuming, require extensive manual manipulation, and result in limited amounts of purified protein, which may complicate the detection of low‐abundance GM protein. A robust sample pretreatment method prior to mass spectrometry (MS) detection of the transgenic protein (5‐enolpyruvylshikimate‐3‐phosphate synthase [CP4 EPSPS]) present in Roundup Ready soya is investigated. Liquid chromatography‐multiple reaction monitoring tandem MS (nano LC‐MS/MS‐MRM) was used for the detection and quantification of CP4 EPSPS. Gold nanoparticles (AuNPs) and concanavalin A (Con A)‐immobilized Sepharose 4B were used as selective probes for the separation of the major storage proteins in soybeans. AuNPs that enable the capture of cysteine‐containing proteins were used to reduce the complexity of the crude extract of GM soya. Con A‐sepharose was used for the affinity capture of β‐conglycinin and other glycoproteins of soya prior to enzymatic digestion. The methods enabled the detection of unique peptides of CP4 EPSPS at a level as low as 0.5% of GM soya in MRM mode. Stable‐isotope dimethyl labeling was further applied to the quantification of GM soya. Both probes exhibited high selectivity and efficiency for the affinity capture of storage proteins, leading to the quantitative detection at 0.5% GM soya, which is a level below the current European Union's threshold for food labeling. The square correlation coefficients were greater than 0.99. The approach for sample preparation is very simple without the need for time‐consuming protein prefractionation or separation procedures and thus presents a significant improvement over existing methods for the analysis of the GM soya protein.
Compressive force‐induced autophagy in periodontal ligament cells downregulates osteoclastogenesis during tooth movement
Authors: Chen Liyuan , Mo Shenzheng , Hua Yongmei 
Published: May 2019

AbstractBackgroundAutophagy has recently emerged as a protective mechanism in response to compressive force and an important process in maintenance of bone homeostasis. It appears to be involved in the degradation of osteoclasts, osteoblasts, and osteocytes. The aim of this study was to investigate the role of compressive force‐induced autophagy in periodontal ligament (PDL) cells in regulating osteoclastogenesis of orthodontic tooth movement (OTM).MethodsAn OTM model and compressive force on PDL cells were employed to investigate the expression of autophagy markers in vivo and in vitro, respectively. Autophagosomes and autolysosomes were observed in PDL cells by transmission electron microscope (TEM) and autophagy LC3 double labelling. 3‐Methyladenine (3‐MA) and rapamycin were respectively used to inhibit and promote autophagy, and the effect of autophagy on osteoclastogenesis was explored via microcomputed tomography, hematoxylin and eosin (H&E) staining, histochemistry of titrate‐resistant acid phosphatase, and real‐time polymerase chain reaction (RT‐PCR) in vivo. Receptor activator of nuclear factor‐kappa B ligand/osteoprotegerin (RANKL/OPG) was investigated by RT‐PCR and ELISA in vitro.ResultsOrthodontic force‐induced autophagy was prominent on the pressured side of PDL tissues. Administration of 3‐MA downregulated bone density and upregulated osteoclasts, while rapamycin had reverse results in OTM. The autophagy activity increased initially then decreased in PDL cells during compressive force application and responded to light force. In PDL cells, administration of 3‐MA upregulated while rapamycin downregulated the RANKL/OPG ratio.ConclusionAutophagy is activated by compressive force in PDL cells. Besides, it could modulate OTM by negatively regulating osteoclastogenesis and keep bone homeostasis via RANKL/OPG signaling.
Investigating functional properties of barberry species: an overview
Authors: Sarraf Mozhdeh , Beig Babaei Adel , Naji‐Tabasi Sara 
Published: May 2019

AbstractThe introduction of new crops and the development of the use of wild plants creates the potential to diversify global food production and better enable local adaptation to the diverse and changing environments that humans inhabit. Barberry is widely distributed worldwide and is recognized as a valuable plant. In this review, we summarize the functional compounds and nutraceutical features of barberry species. Barberry plants have fruits, flowers, leaves, stems and roots. All of these parts contain very important compounds, such as anthocyanins, alkaloids, flavonoids, phenolic compounds, vitamins and minerals, etc., which have been used for many years in traditional medicine. These compounds have a strong impact on human health and can be used as a painkiller, as well as for the relief of fever, diarrhea and vomiting. They are also useful for curing liver and vascular problems and preventing many diseases. One of the most important functional compounds in the barberry plant is berberine, which exists in its different parts. Studies have shown that berberine in barberry reduces cholesterol and blood glucose. It can help to prevent Alzheimer's and neoplastic diseases. Furthermore, it has antimicrobial, antifungal and antioxidant properties. According to the investigations, barberry plant derivations can be considered as useful additives and functional compounds in various industries, especially in the food industry. © 2019 Society of Chemical Industry
Quantitative Sonoelastographic Assessment of the Normal Uterus Using Shear Wave Elastography: An Initial Experience
Authors: Manchanda Smita , Vora Zainab , Sharma Raju , Hari Smriti , Das Chandan Jyoti , Kumar Sunesh , Kachhawa Garima , Khan Maroof Ahmad 
Published: May 2019

ObjectivesTo describe the sonoelastographic characteristics of the normal endometrium, myometrium, and cervix and to assess their variability with age and different menstrual phases.MethodsA total of 56 women were enrolled in this prospective study, who underwent transvaginal ultrasound examinations, including B‐mode imaging and shear wave elastography. The elasticity parameters (in kilopascals) of the normal endometrium, myometrium, and cervix were studied. The variability of the mean elasticity value of the endometrium in different menstrual phases and age groups was analyzed. The variability of the mean elasticity of the cervix across different age groups was also studied.ResultsThe mean age of the participants was 40 years (range, 25–69 years). The normal mean elasticity values ± SDs were 25.54 ± 8.56 kPa for the endometrium, 40.24 ± 8.59 kPa for the myometrium, and 18.90 ± 4.22 kPa for the cervix. A mean endometrial‐to‐myometrial elasticity ratio was calculated, which was found to be 0.65 ± 0.22. There was no significant difference in the mean endometrial elasticity values for women in different menstrual phases (P = .176) or in different age groups (P = .376). There was no significant difference in the mean cervical elasticity with age (P = .192).ConclusionsShear wave elastography is a promising adjunct to ultrasound for the evaluation of the uterus, and the results from this study may provide normal data, which may further help in diagnosing various uterine diseases.