bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparing the Nurse of the Future: Emergent Themes in Online RN-BSN Education
Authors: Perfetto Linda M. 
Published: August 2018

Abstract

AIM
Registered nurse to baccalaureate in nursing (RN-BSN) programs hold the second lowest average graduation rate of US nursing programs. Online education is often cited as a good fit for the working nurse for its convenience, accessibility, and flexibility. With a focus on supporting persistence in RN-BSN programs, this research sought to answer the question, What are the best practices for distance/online/hybrid RN to BSN program curriculum and instruction?

BACKGROUND
Distance/online/hybrid approaches are a component of most RN-BSN programs and may hold promise for working nurses balancing multiple responsibilities while in school.

METHOD
The Garrard Matrix Method was aligned with the work of Whittemore and Knafl to synthesize research that addressed the question.

RESULTS
Four themes emerged through this synthesis.

CONCLUSION
The findings serve as the beginning of a comprehensive guide on the subject.
Effectiveness of Fertility Awareness–Based Methods for Pregnancy Prevention
Authors: Peragallo Urrutia Rachel , Polis Chelsea B. , Jensen Elizabeth T. , Greene Margaret E. , Kennedy Emily , Stanford Joseph B. 
Published: August 2018

OBJECTIVE:
To summarize best available prospective data on typical and perfect use effectiveness of fertility awareness–based methods for avoiding pregnancy.

DATA SOURCES:
We conducted a systematic review of studies published in English, Spanish, French, or German by June 2017 in MEDLINE, EMBASE, CINAHL, Web of Science, and ClinicalTrials.gov.

METHODS OF STUDY SELECTION:
We reviewed 8,755 unique citations and included 53 studies that contained 50 or greater women using a specific fertility awareness–based method to avoid pregnancy, calculated life table pregnancy probabilities or Pearl rates, and prospectively measured pregnancy intentions and outcomes. We systematically evaluated study quality.

TABULATION, INTEGRATION, AND RESULTS:
Of 53 included studies, we ranked 0 high quality, 21 moderate quality, and 32 low quality for our question of interest. Among moderate-quality studies, first-year typical use pregnancy rates or probabilities per 100 woman-years varied widely: 11.2–14.1 for the Standard Days Method, 13.7 for the TwoDay Method, 10.5–33.6 for the Billings Ovulation Method, 4–18.5 for the Marquette Mucus-only Method, 9.0–9.8 for basal body temperature methods, 13.2 for single-check symptothermal methods, 11.2–33.0 for Thyma double-check symptothermal methods, 1.8 for Sensiplan, 25.6 for Persona, 2–6.8 for the Marquette Monitor-only Method, and 6–7 for the Marquette Monitor and Mucus Method. First-year perfect use pregnancy rates or probabilities among moderate-quality studies were 4.8 for the Standard Days Method, 3.5 for the TwoDay Method, 1.1–3.4 for the Billings Ovulation Method, 2.7 for the Marquette Mucus Method, 0.4 for Sensiplan, 12.1 for Persona, and 0 for the Marquette Monitor.

CONCLUSION:
Studies on the effectiveness of each fertility awareness–based method are few and of low to moderate quality. Pregnancy rates or probabilities varied widely across different fertility awareness–based methods (and in some cases, within method types), even after excluding low-quality studies. Variability across populations studied precludes comparisons across methods.
Rectal Chlamydia trachomatis and Neisseria gonorrhoeae Infections Among Women Reporting Anal Intercourse
Authors: Llata Eloisa , Braxton Jim , Asbel Lenore , Chow Joan , Jenkins Lindsay , Murphy Ryan , Pathela Preeti , Schumacher Christina , Torrone Elizabeth 
Published: August 2018

OBJECTIVE:
To examine the prevalence and treatment of rectal Chlamydia trachomatis and Neisseria gonorrhoeae infections among women reporting receptive anal intercourse in a network of sexually transmitted disease or sexual health clinics and estimate the proportion of missed infections if women were tested at the genital site only.

METHODS:
We conducted a cross-sectional analysis of C trachomatis and N gonorrhoeae test results from female patients reporting receptive anal intercourse in the preceding 3 months during visits to 24 sexually transmitted disease clinics from 2015 to 2016. Primary outcomes of interest were 1) anatomic site-specific C trachomatis and N gonorrhoeae testing and positivity among women attending selected U.S. sexually transmitted disease clinics who reported receptive anal intercourse and 2) the proportion of rectal infections that would have remained undetected if only genital sites were tested.

RESULTS:
Overall, 7.4% (3,743/50,785) of women reported receptive anal intercourse during the 2 years. Of the 2,818 women tested at both the genital and rectal sites for C trachomatis, 292 women were positive (61 genital only, 60 rectal only, and 171 at both sites). Of the 2,829 women tested at both the genital and rectal sites for N gonorrhoeae, 128 women were positive (31 genital only, 23 rectal only, and 74 at both sites). Among women tested at both anatomic sites, the proportion of missed C trachomatis infections would have been 20.5% and for N gonorrhoeae infections, 18.0%.

CONCLUSION:
Genital testing alone misses approximately one fifth of C trachomatis and N gonorrhoeae infections in women reporting receptive anal intercourse in our study population. Missed rectal infections may result in ongoing transmission to other sexual partners and reinfection.
Arthroscopic decompression of the flexor hallucis longus tendon in posttraumatic tendinopathy
Authors: Diab Hossam S. 
Published: August 2018

Background:
Tenosynovitis of the flexor hallucis longus (FHL) tendon is more frequent than previously reported, and the condition is often overlooked or misdiagnosed. Overuse in ballet dancers or competitive runners was believed to be the main triggering factor. Recent advances in diagnostic modalities have shown a wide occurrence in nonathletes. The purpose of this study was to evaluate arthroscopic decompression of the FHL tendon in posttraumatic tenosynovitis.

Methods:
Nine consecutive patients with posttraumatic flexor hallucis longus stenosing tenosynovitis were treated and enrolled in this prospective study. All patients dated their complaint to previous ankle fracture or major sprain. The standard procedure included posterior ankle arthroscopy, thorough debridement of posterior adhesions, and adequate decompression of the tendon at the fibroosseous tunnel. Patients were evaluated for functional outcome through both Foot and Ankle Outcome Score (FAOS) and Ankle-Hindfoot Scale.

Results:
The mean FAOS score at 1-year follow-up improved from a preoperative mean of 72.56 (SD 4.43) to a postoperative mean of 87.33 (SD 4.03), which is considered to be extremely statistically significant with a P value less than 0.0001. The mean Ankle-Hindfoot Scale improved from a preoperative mean of 71.78 (SD 3.77) to a postoperative mean of 85.33 (SD 5.94). All patients reported being fully satisfied with an overall satisfaction score of 9.42.

Conclusions:
Flexor hallucis longus stenosing tenosynovitis is more frequent than previously thought and should be considered in patients with posterior ankle pain especially if a history of ankle trauma exists.
Early Revision Surgery for Tibial Plateau Fractures
Authors: Kloen Peter , van Wulfften Palthe Olivier D. R. , Nützinger Jorn , Donders Johanna C. E. 
Published: August 2018

Objective:
To describe patients' outcomes after revision of tibial plateau fracture fixation within 12 months of the initial surgical procedure. To assess differences in objective outcome scores [International Knee Documentation Committee (IKDC), short form-36, arthrosis score, physical examination] depending on whether patients were treated for malreduction, malunion, or nonunion.

Design:
Retrospective case series.

Patients:
Twenty-seven patients who underwent revision within 1 year of primary surgery and with a minimum follow-up of 1 year.

Main Outcome Measurement:
IKDC Subjective Knee Form, alignment, osteoarthritis, timed up and go test, range of motion, and physical and mental health (using the short form-36 survey).

Results:
At the most recent follow-up, the mean IKDC subjective knee score of all patients within the study group was 62 (SD 17). In the malreduction group, the mean was 71 (SD 17), in the malunion group the mean was 56 (SD 17), and in the nonunion group, the mean was also 56 (SD 12; χ2 0.94; P = 0.624). Comparing the malreduction group with the malunion and nonunion groups combined, there was a significantly higher IKDC score (P = 0.019) in the malreduction group.

Conclusion:
A suboptimal outcome after open reduction and internal fixation of a tibial plateau fracture is common. If the underlying cause of the fracture is malreduction, malunion, or a nonunion, salvage of the joint without a knee replacement is worthwhile. When using a strategy incorporating revision plate fixation, osteotomy (intra- and/or extraarticular), debridement, and bone grafting when needed, patients should experience favorable long-term outcomes, including less residual pain and functional limitations.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
A Novel Inexpensive Technique to Seal Negative Pressure Wound Therapy on External Fixation Devices
Authors: Caputo Glenda G. , Marchetti Alberto , Governa Maurizio , Dalla Pozza Edoardo 
Published: August 2018

Summary:
Negative pressure wound therapy, a tool widely applied to treat lower limb traumas, is useful in reconstructive procedures. However, obtaining an airtight vacuum seal when using a negative pressure dressing around an external fixation device can be complicated and time-consuming. The plastic drape seldom adheres to screws, pins, or wires and, as such, the vacuum seal is jeopardized. In surgical departments, colostomy paste is widely used, readily available, and applied where pins and wires make contact with the plastic drape. It is a fast, practical, and inexpensive method of preventing air leakage. In conclusion, to obtain an airtight seal between the skin and an external fixation device, colostomy paste may be used to ensure an optimal tight seal, even for complex and extended wounds, for 3–5 days without complications or the requirement for additional dressing changes. Furthermore, it is inexpensive, readily available, simple to use, and quick to apply.
Granulomatous Rosacea Versus Lupus Miliaris Disseminatus Faciei—2 Faces of Facial Granulomatous Disorder: A Clinicohistological and Molecular Study
Authors: Chougule Abhijit , Chatterjee Debajyoti , Yadav Rakesh , Sethi Sunil , De Dipankar , Saikia Uma Nahar 
Published: August 2018

Abstract:
Granulomatous rosacea (GR) and lupus miliaris disseminatus faciei (LMDF) are 2 forms of facial granulomatous diseases. Although they show some morphological overlap, they have distinct clinical presentation. This study was performed to demonstrate the clinical and histological features of GR and LMDF and to establish their relationship to tuberculous etiology by molecular technique. All the cases of GR (n = 20) and LMDF (n = 10) diagnosed on skin biopsy over the past 6 years were reviewed along with their clinical detail. Polymerase chain reaction (PCR) was performed using primers specific for Mycobacterium tuberculosis. The mean age of patients with GR was 45 years 10 months (range 18–75 years) as compared to 33 years 5 months (range 18–57 years) in patients with LMDF. The GR cases comprised 13 men and 7 women patients, whereas all 10 LMDF cases were seen in men. GR cases had papular lesion over an erythematous base on face, whereas LMDF cases had papular/nodular/nodulocystic lesions on the face and neck. Histologically, GR cases showed small granulomas without necrosis in a background of variable lymphoid infiltrate and dilated capillaries, whereas LMDF showed large granulomas with caseous necrosis and minimal inflammation. Five cases (25%) of GR showed degenerating Demodex folliculorum mites. No case of GR or LMDF showed positivity for mycobacterial polymerase chain reaction. Despite some similarities, GR and LMDF show distinct clinical and histological features. Thus, LMDF is a distinct clinicopathological entity separate from the GR, with different etiopathogenesis. However, none of the conditions are related to a tuberculous etiology.
Long-term Functional Outcome After Right-Sided Complete Mesocolic Excision Compared With Conventional Colon Cancer Surgery: A Population-Based Questionnaire Study
Authors: Bertelsen Claus Anders , Larsen Helene M. , Neuenschwander Anders U. , Laurberg Søren , Kristensen Bent , Emmertsen Katrine J. 
Published: August 2018

BACKGROUND:Complete mesocolic excision improves the long-term outcome of colon cancer but might carry a risk of bowel dysfunction.OBJECTIVE:This study aimed to investigate whether right-sided complete mesocolic excision is associated with an increased risk of long-term bowel dysfunction and reduced quality of life compared with conventional colon cancer resections.DESIGN:Data were extracted from a population-based study comparing complete mesocolic excision and conventional colon cancer resections and from a national questionnaire survey regarding functional outcome.SETTINGS:Elective right-sided colon resections for stage I to III colon adenocarcinoma were performed at 4 university colorectal centers between June 2008 and December 2014.PATIENTS:Seven hundred sixty-two patients were eligible to receive the questionnaire in November 2015.MAIN OUTCOME MEASURES:The primary outcomes measured were the risk of diarrhea (Bristol stool scale score of 6–7), 4 or more bowel movements daily, and the impact of bowel function on quality of life. Secondary outcomes were other bowel symptoms, chronic pain, and quality of life measured by the European Organisation for Research and Treatment of Cancer QLQ-C30.RESULTS:One hundred forty-one (63.8%) and 324 (59.9%) patients undergoing complete mesocolic excision and conventional resections responded after a median of 3.99 (interquartile range, 2.11–5.32) and 4.11 (interquartile range, 3.01–5.53) years (p= 0.04). Complete mesocolic excision was not associated with increased risk of diarrhea (adjusted OR, 1.07; 95% CI, 0.57–1.95;p= 0.84), 4 or more bowel movements daily (adjusted OR, 1.16; 95% CI, 0.57–2.24;p= 0.68), or lower quality of life (adjusted OR, 0.84; 95% CI, 0.49–1.40;p= 0.50). Complete mesocolic excision was associated nonsignificantly with nocturnal bowel movements, but not associated with chronic pain or other secondary outcomes.LIMITATIONS:This study was limited by the retrospective design with unknown baseline symptoms. Responding patients were younger but without obvious selection bias. The outcome “diarrhea” seemed somehow sensitive to information bias.CONCLUSION:Right-sided complete mesocolic excision seems associated with neither bowel dysfunction nor impaired quality of life when compared with conventional surgery. SeeVideo Abstractat http://links.lww.com/DCR/A665.
Should a History of Extraperitoneal Disease Be a Contraindication to Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Colorectal Cancer Peritoneal Metastases?
Authors: Baratti Dario , Kusamura Shigeki , Iusco Domenico , Cotsoglou Christian , Guaglio Marcello , Battaglia Luigi , Virzì Salvatore , Mazzaferro Vincenzo , Deraco Marcello 
Published: August 2018

BACKGROUND:
Survival improvements have been reported in selected patients affected by colorectal peritoneal metastases who were undergoing cytoreductive surgery with intraperitoneal hyperthermic chemotherapy. Treatment of peritoneal metastases associated with extraperitoneal disease is still controversial.

OBJECTIVE:
We assessed the prognostic impact of a history of extraperitoneal disease that was curatively treated either at the same time as or before the onset of peritoneal metastases.

DESIGN:
We reviewed 2 prospective databases. Peritoneal involvement was scored by Peritoneal Cancer Index.

SETTINGS:
Our study was conducted in 2 high-volume peritoneal malignancy management institutions.

PATIENTS:
A total of 148 patients with peritoneal metastases were included. In 27 patients, extraperitoneal disease involving the liver (n = 23), lung (n = 1), both lung and liver (n = 2), or inguinal lymph nodes and liver (n = 1) was curatively treated either simultaneously with peritoneal metastases (n = 22) or before their onset (n = 5).

INTERVENTIONS:
All of the macroscopic tumors were removed by means of peritonectomy procedures and visceral resections. Microscopic residual disease was treated by mitomycin C/cisplatin-based hyperthermic intraperitoneal chemotherapy.

MAIN OUTCOME MEASURES:
Overall survival was the primary outcome measure.

RESULTS:
After a median follow-up of 34.6 months (95% CI, 22.6–65.7 mo), 5-year survival of patients treated for both peritoneal and extraperitoneal disease versus peritoneal metastases alone was 16.5% versus 52.0% (p = 0.019). After multivariate analysis, reduced survival correlated with extraperitoneal disease (p = 0.001), Peritoneal Cancer Index >19 (p = 0.004), and peritoneal residual disease >2.5 mm (p = 0.018). Three prognostic groups were defined, and median survival was not reached for group 1 (Peritoneal Cancer Index ≤19 and no extraperitoneal disease), reached in 27.0 months for group 2 (Peritoneal Cancer Index ≤9 and extraperitoneal disease), and reached in 11.6 months for group 3 (Peritoneal Cancer Index >19 and no extraperitoneal disease or Peritoneal Cancer Index >9 and extraperitoneal disease).

LIMITATIONS:
The main study limitation is its observational nature.

CONCLUSIONS:
A history of extraperitoneal disease is associated with poorer prognosis. However, survival benefit may be obtained in selected patients with limited peritoneal involvement. See Video Abstract at http://links.lww.com/DCR/A655.
Management of Large Cecal Polyps: When Can the Ileocecal Valve Be Spared?
Authors: Kulaylat Audrey S. , Boltz Melissa M. , Moyer Matthew , Mathew Abraham , McKenna Kevin , Messaris Evangelos 
Published: August 2018

BACKGROUND:
Endoscopic mucosal resection comprises the first-line treatment for large cecal polyps. With up to 14% of unresectable colonic polyps harboring malignancy, the management of endoscopically unresectable cecal polyps remains an oncologic right hemicolectomy, which can be associated with substantial postoperative morbidity.

OBJECTIVE:
This study compares the outcomes of patients with cecal polyps who underwent either endoscopic mucosal resection, a cecectomy, or a right hemicolectomy.

DATA SOURCES:
Patients undergoing either endoscopic mucosal resection, partial cecectomy, or right hemicolectomy from 2008 to 2017 at a single tertiary care institution were selected.

STUDY SELECTION:
This was a retrospective cohort study.

MAIN OUTCOME MEASURES:
The primary outcomes measured were the rate of malignancy, complication rate, estimated blood loss, and hospital length of stay between surgical cohorts.

RESULTS:
One hundred twenty-nine patients with cecal polyps were identified, of which 52 were referred for surgery. Nineteen underwent partial cecectomy and 33 (27.3%) underwent right hemicolectomy. Two patients undergoing cecectomy required conversion to hemicolectomy because the resected specimen did not contain the polyp. The 2 surgical cohorts did not differ significantly regarding age, sex, or ASA classification. Procedural complication rates were higher among those undergoing hemicolectomy compared with those undergoing cecectomy (37.1% versus 5.9%, p = 0.02). Estimated blood loss (50 vs 10 mL, p = 0.02), operative duration (98 vs 76 minutes, p = 0.009), and length of stay (4 vs 2 days, p < 0.001) were higher in patients undergoing hemicolectomy than in those undergoing cecectomy. No invasive malignancies were identified on final pathology within the cecectomy cohort.

LIMITATIONS:
Single-institution data and retrospective design were limitations of this study.

CONCLUSIONS:
In tertiary centers, the majority of large cecal polyps are benign and can be addressed by using endoscopic mucosal resection. When involvement of the appendiceal orifice or ileocecal valve precludes endoscopic treatment, surgical resection is the standard of care. In the subset of cases not involving the ileocecal valve and without preoperative evidence of malignancy, partial cecectomy spares the ileocecal valve and can offer reduced postoperative morbidity compared with a formal right hemicolectomy. See Video Abstract at http://links.lww.com/DCR/A674.
Validation of the 10-item Cervantes Scale in middle-aged Portuguese women: paper-and-pencil and online format assessment of menopause-related symptoms
Authors: Pimenta Filipa , Albergaria Rita , Marôco João , Leal Isabel , Chedraui Peter , Pérez-López Faustino R. 
Published: August 2018

Abstract

Objective:
The aim of the study was to validate the Portuguese language version of the 10-item Cervantes Scale (CS-10), a self-reporting instrument that assesses menopausal symptoms, and to compare the results (both symptom severity and multigroup invariance) of middle-aged women who completed the questionnaire in paper-and-pencil format (PPF) or in the online format (OF).

Methods:
A total of 292 women, aged 45 to 65 years, completed the questionnaires (PPF = 66; OF = 226). Construct (factorial and convergent) and external validity, as well as reliability and psychometric sensitivity were studied. Multigroup confirmatory factor analysis was performed to compare PPF with OF, regarding the measure's invariance.

Results:
The CS-10 showed good psychometric properties (ie, factor and external validity), as well as good sensitivity and reliability. The association with the Utian Quality of Life Scale (UQoLS) was significant and positive, though weak. The measured structure was invariant when comparing both subsamples (PPF and OF), evidencing an equivalent structure in both. No differences in reported symptoms were observed between the two subgroups.

Conclusions:
The Portuguese language version of the CS-10 rendered data with good psychometric properties in a sample of middle-aged Portuguese women. Therefore, it can be used in both clinical and community settings. The weak association between both instruments (UQoLS and CS-10) might be due to the different conceptualization of the quality of life construct: the CS-10 focuses on symptom severity, whereas the UQoLS assesses domains such as work-related or health-related behaviors.
HOW TO MEASURE THE LARGEST BASAL DIMENSION OF CHOROIDAL MELANOMA
Authors: França Maira , Ayres Bernadete , Parrish Elizabeth , Demirci Hakan 
Published: August 2018

Purpose:
To identify the most accurate ultrasonographic technique to measure the largest basal dimension (LBD) of choroidal melanoma.

Methods:
B-scan ultrasound images were retrospectively reviewed in 99 eyes of 99 choroidal melanoma patients. The LBD was measured using one, two, and three straight lines along the inner and outer sclera. Theoretical arc length, calculated using trigonometry formulas based on the spherical model with the axial length as the sphere diameter, was used for comparisons with the actual measurements using straight lines.

Results:
For straight-line measurements in the inner sclera, the lowest error was found when using two straight-line measurements (P = 0.118). Differences in measurement using one-segment or three-segment measurements as compared with the theoretical arc length were found to be statistically significant (P < 0.001 in both cases). For tumors with LBD smaller than 12 mm, the absolute error, compared with the theoretical arc length, was smaller than 1 mm. In the outer sclera, the smallest errors were also found for measurements using two straight-line segments; however, it was statistically different than the theoretical inner arc length (P < 0.001).

Conclusion:
When using ultrasound to estimate LBD of ocular tumors, 2 straight-line measurements should be used when LBD is larger than 12 mm. For tumors with LBD smaller than 12 mm, measurements using 1 straight-line segment can provide accurate estimates.