bluuebunny/crossref_metadata_2025_split huggingface dataset:
A practical approach to measuring the impacts of stockouts on demand
Authors: Kim Sungil , Kim Heeyoung , Lu Jye-Chyi 
Published: May 2019

Purpose
This paper aims to propose a statistical method to measure the impacts of stockouts on demand, using a segmented linear regression model.

Design/methodology/approach
The proposed method is applied to data sets from large retail chains to measure the impacts of stockouts of an item on substitute items. The measured impacts of stockouts can be used to estimate the true demand of the sold-out item by recovering the lost demand (turned-away demand), as well as to estimate the true demand of the substitute item by reducing the extra demand.

Findings
This study found that estimated true demand by the proposed method improves sales forecasting and calculation of the annual expected revenue.

Originality/value
A new method to measure the impacts of stockouts on the demand of substitute items was proposed. The proposed method is practical, in that, it is conceptually simple, computationally efficient and applicable in general scenarios. Also, the proposed method is scalable for larger data sets.
CCP resolution, loss allocation and shareholders’ rights
Authors: Peters Marc 
Published: May 2019

Purpose
Central clearing counterparties’ (CCPs) specific loss allocation mechanism is reflected in the specific resolution regime designed at the international level. At the same time, international guidance texts require equity to bear losses first in resolution. This creates a tension that immediately exposes resolution authorities to potential claims from CCPs’ shareholders. The purpose of this paper is to seek possible options to solve that tension, thereby enabling a workable and credible resolution regime for CCPs.

Design/methodology/approach
The paper analyses the current tension between the no creditor worse-off (NCWO) counterfactual for CCPs and the “equity bears first losses in resolution” principle. It then considers six different options to solve this tension, ranging from a revision of insolvency law to the modification of the loss-allocation structure.

Findings
The paper concludes that additional layers of capital contribution, adapting the contractual arrangements or articles of incorporation and/or the creation of a specific NCWO counterfactual for shareholders could help in solving the identified tension.

Practical implications
The paper presents options on how to design a workable and credible resolution regime for CCPs that would enable resolution authorities to exercise their powers and have the flexibility to intervene at an early stage in recovery to prevent the exhaustion of available financial resources, without being unduly exposed to claims.

Originality/value
The paper contributes to the literature on CCP resolution. It is one of the first to analyse the articulation between the loss-allocation structure of CCPs, the NCWO principle and shareholders’ rights. We hope that this paper will encourage further literature to develop on this important subject.
Environmental impact of economic growth, emission and FDI: systematic review of reviews
Authors: Saini Neha , Sighania Monica 
Published: May 2019

PurposeThe purpose of this paper is to organize the detailed review of economic growth, carbon emission and foreign capital inflows and its impact on the environment. Another objective of the study is to provide the comprehensive bibliography and to analyze the findings and results of the studies undertaken in review.Design/methodology/approachThis paper examined 111 research papers from a sample of thousands of papers, based on inclusion criteria, in this area of research. These 111 research papers are categorized on the basis of several factors to know the status of research on this topic.FindingsThis study is based on economic development and carbon emission and its impact on the environment. We tried to gather all the available facts based on this topic and found that the topic is gaining high relevance in the present scenario because of the growing pace of development in developing countries. Most of the studies supported the environmental Kuznets curve hypothesis and we also found that significant amount of literature is available which supports cleaner FDI as a measure to mitigate the negative effects of economic growth on the ecological environment.Originality/valueBased on the literature review from various sources, this study provides the collection, classification and comprehensive bibliography on this topic, which may be helpful for stakeholders such as academicians, researchers and policymakers working particularly in this area of research.
Effects of Sustained‐Release Beraprost in Patients With Primary Glomerular Disease or Nephrosclerosis: CASSIOPEIR Study Results
Authors: Nakamoto Hidetomo , Yu Xue‐Qing , Kim Suhnggwon , Origasa Hideki , Zheng Hongguang , Chen Jianghua , Joo Kwon Wook , Sritippayawan Suchai , Chen Qinkai , Chen Hung‐Chun , Tsubakihara Yoshiharu , Tamai Hirofumi , Song Sang Heon , Vaithilingam Indralingam , Lee Kang Wook , Shu Kuo‐Hsiung , Hok‐King Lo Stanley , Isono Masanao , Kurumatani Hajimu , Okada Kiyonobu , Kanoh Hiroyuki , Kiriyama Takashi , Yamada Shunsuke , Fujita Toshiro 
Published: May 2019

AbstractTRK‐100STP, a sustained‐release preparation of the orally active prostacyclin analogue beraprost sodium, targets renal hypoxia. This study aimed to show the superiority of TRK‐100STP over placebos in patients with chronic kidney disease (with either primary glomerular disease or nephrosclerosis) to determine the recommended dose. CASSIOPEIR (Chronic Renal Failure Asian Study with Oral PGI2 Derivative for Evaluating Improvement of Renal Function) was a randomized, double‐blind, placebo‐controlled study conducted at 160 sites in seven Asia‐Pacific countries and regions. Eligible patients (n = 892) were randomized to TRK‐100STP 120, 240 μg, or placebo for a treatment period of up to 4 years. The primary efficacy endpoint was time to first occurrence of a renal composite: doubling of serum creatinine or occurrence of end‐stage renal disease. No significant differences were observed in composite endpoints between TRK‐100STP and placebo (P = 0.5674). Hazard ratios (95% CI) in the TRK‐100STP 120 and 240 μg vs. placebo groups were 0.98 (0.78, 1.22) and 0.91 (0.72, 1.14), respectively. The overall incidence of adverse events and adverse drug reactions was comparable between treatment arms.
Corrosion casting in anatomy: Visualizing the architecture of hollow structures and surface details
Authors: Cornillie Pieter , Casteleyn Christophe , von Horst Christoph , Henry Robert 
Published: May 2019

AbstractCorrosion casting is the technique by which a solid, negative replica is created from a hollow anatomical structure and liberated from its surrounding tissues. For centuries, different types of hardening substances have been developed to create such casts, but nowadays, thermosetting polymers are mostly used as casting medium. Although the principle and initial set‐up are relatively easy, producing high‐quality casts that serve their intended purpose can be quite challenging. This paper evaluates some of the more popular casting resins that are currently available and provides a step‐by‐step overview of the corrosion casting procedure, including surface casts of anatomical structures. Hurdles and pitfalls are discussed, along with possible solutions to circumvent them, based on personal experience by the authors.
Clinical factors associated with peanut allergy in a high‐risk infant cohort
Authors: Sicherer Scott H. , Wood Robert A. , Perry Tamara T. , Jones Stacie M. , Leung Donald Y. M. , Henning Alice K. , Dawson Peter , Burks A. Wesley , Lindblad Robert , Sampson Hugh A. 
Published: May 2019

AbstractBackgroundPrognostication of peanut allergy (PNA) is relevant for early interventions. We aimed to determine baseline parameters associated with the development of PNA in 3‐ to 15‐month‐olds with likely egg and/or milk allergy, and/or moderate to severe atopic dermatitis (AD) and a positive egg/milk skin prick test (SPT), but no known PNA.MethodsThe primary endpoint was PNA [confirmed/convincing diagnosis or last classified as serologic PNA (<2 years, ≥5 kUA/L, otherwise ≥14 kUA/L, peanut IgE)] among 511 participants (median follow‐up, 7.3 years). Associations were explored with univariate logistic regression; factors with P < 0.15 were analyzed by stepwise multiple logistic regression, using data stratified by PNA status and randomly assigned to development and validation datasets.Results205/511 (40.1%) had PNA. Univariate factors associated with PNA (P < 0.01) included increased AD severity, larger egg and peanut SPT, greater egg, milk, peanut, Ara h1‐h3 IgE, higher peanut IgG and IgG4, and increased pregnancy peanut consumption. P‐values were between 0.01 and 0.05 for younger age, non‐white race, lack of breastfeeding, and increased lactation peanut consumption. Using a development dataset, the multivariate model identified younger age at enrollment, greater peanut and Ara h2 IgE, and lack of breastfeeding as prognosticators. The final model predicted 79% in the development and 75% in the validation dataset (AUC = 0.83 for both). Models using stricter or less strict PNA criteria both found Ara h2 as predictive.ConclusionsKey factors associated with PNA in this high‐risk population included lack of breastfeeding, age, and greater Ara h2 and peanut‐specific IgE, which can be used to prognosticate outcomes.
Satellite image texture for the assessment of tropical anuran communities
Authors: Sugai Larissa Sayuri Moreira , Sugai José Luiz Massao Moreira , Ferreira Vanda Lucia , Silva Thiago Sanna Freire 
Published: May 2019

AbstractThe relationship between environmental heterogeneity and biodiversity represents a cornerstone of ecological research. While environmental descriptors over large extents usually have medium‐to‐low spatial resolution, in situ measures provide accurate information for limited areas, and a gap remains in providing remote descriptors that represent local environmental structure. Texture from satellite images can represent fine‐scale heterogeneity over wide spatial coverage, but to date, it has mostly been used to predict general aspects of species diversity, such as richness. Here, we assess the utility of image textures from high‐resolution satellite images (RapidEye 3A) and in situ variables to predict differences in the composition of anuran communities in a tropical savanna (Cerrado) of Brazil. While in situ measures accounted for compositional differences in the whole community, two measures of image textures were associated only with the variation of species within the Hylidae family (adj. R² = 0.16 and 0.14). Comparatively, image textures predicted ~2/3 of the variation explained by in situ measures (adj. R² = 0.23). When both approaches were combined, a greater compositional variation was achieved (adj. R² = 0.28), with 1/5 of it shared by both in situ and textures, and 1/5 attributed solely to texture. Our findings suggest that image texture can complement the assessment of environmental heterogeneity acting on the assembly of local anuran communities. This approach can be valuable for explicitly including spatial heterogeneity in biological assessments over broad spatial extents, especially for biological groups strongly filtered by environmental conditions.Abstract in Portuguese is available with online material.
Neurogenic inflammation in periimplant and periodontal disease: A case–control split‐mouth study
Authors: Sert Sertaç , Sakallioğlu Umur , Lütfioğlu Müge , Aydoğdu Ahmet , Acarel Eser , Günaydın Murat 
Published: May 2019

AbstractObjectiveAlthough the regulatory effects of substance‐P (SP), neurokinin‐A (NKA), calcitonin gene‐linked peptide (CGRP) and neuropeptide‐Y (NPY) on periodontal inflammatory responses have been described, the effects of these neuropeptides on healthy and diseased periimplant tissues are not clearly defined.Materials and methodsThirty‐nine implants loaded at least for 12 months with their symmetrically matching teeth were evaluated and compared by a split‐mouth study design. Six study groups were created in this regard as follows: group 1 (healthy periodontal tissues), group 2 (healthy periimplant tissues), group 3 (gingivitis), group 4 (periimplant mucositis), group 5 (periodontitis) and group 6 (periimplantitis). Clinical examinations included Silness–Löe plaque index, Löe–Silness gingival index, bleeding on probing, probing pocket depth and clinical attachment level measurements. Gingival crevicular fluid and periimplant sulcular fluid samples were collected, and the concentrations of neuropeptides were determined by enzyme‐linked immunosorbent assay. Their levels and correlations were investigated together with the clinical parameters.ResultsNeuropeptide levels were different in the teeth and implant groups according to the periodontal status (p < 0.001). SP and NKA levels were increased, whereas CGRP and NPY levels were decreased in the diseased states. There were no differences between the neuropeptide levels of matching teeth and implants (groups 1–2, groups 3–4 and groups 5–6; p > 0.05).ConclusionOur study demonstrated the presence of local neuropeptides in healthy and diseased periimplant tissues. The neurogenic inflammatory responses were also found to be similar in both periimplant and periodontal tissues.
Precipitation and tree cover gradients structure avian alpha diversity in North‐western Costa Rica
Authors: Echeverri Alejandra , Frishkoff Luke O. , Gomez Juan Pablo , Zook Jim R. , Juárez Pedro , Naidoo Robin , Chan Kai M. A. , Karp Daniel S. 
Published: May 2019

AbstractAimChanges in climate and land use are modifying biodiversity worldwide. Yet it remains unclear how both drivers interact to structure communities and determine patterns in taxonomic, phylogenetic and functional diversity at local scales. We focused on bird diversity and asked: how do precipitation and forest cover gradients interactively structure these elements of avian diversity?LocationGuanacaste, North‐western Costa Rica.MethodsWe quantified changes in the abundance and composition of bird communities along independent gradients of regional precipitation, local forest cover and landscape forest cover that serve as proxies for climate drying and habitat conversion. We conducted point counts at 150 sites and statistically accounted for imperfect detection to test how environmental variation shaped community‐wide diversity metrics.ResultsWe found that the three dimensions of diversity diverged in their responses to environmental gradients. Specifically, species richness increased linearly with precipitation, reached maximum values with intermediate tree cover at local scales and peaked at high levels of landscape tree cover. While phylogenetic diversity did not vary strongly across any gradient, functional diversity increased monotonically with both local and landscape‐level tree cover. Maximum values of functional diversity only occurred in large patches of forest where the tree cover was >75% at both local and landscape scales. Contrary to our expectations, we did not detect significant interactions between precipitation and tree cover gradients on any metric of local bird diversity.Main conclusionsOur findings suggest that taxonomic diversity was more sensitive to environmental gradients than functional and phylogenetic diversity. The lack of synergies between precipitation and forest cover gradients on alpha diversity, at least in this system, simplifies the prospects of predicting future biodiversity change at local scales as our results suggest that climate change and land use act independently of one another.
Skill‐up study of systemic endoscopic examination technique using narrow band imaging of the head and neck region of patients with esophageal squamous cell carcinoma: Prospective multicenter study
Authors: Okamoto Naoki , Morimoto Hiroyuki , Yamamoto Yoichi , Kanda Keisuke , Nankinzan Rino , Kasamatsu Shingo , Yoshimura Shigenobu , Kan Motoyasu , Nakano Akira , Hosaka Shosuke , Watanabe Yuuka , Arahata Kyoko , Toyama Yuzo , Okamura Ayumi , Yamaguchi Taketo , Yano Tomonori 
Published: May 2019

ObjectiveTo evaluate the usefulness of a training program on endoscopic head and neck surveillance for beginner endoscopists.MethodsThis prospective multicenter study included 13 beginner endoscopists from 10 institutions who received training in systematic observation techniques and diagnostic criteria, and the training involved hands‐on learning. Between May 2016 and February 2017, enrolled patients with current or previously diagnosed esophageal squamous cell carcinomas underwent head and neck surveillance using narrow band imaging (NBI) endoscopy, and histologically confirmed head and neck squamous cell carcinoma (HNSCC) detection rates, endoscopic image quality, and examination times were compared before (group A) and after (group B) the training program. Maximum possible score for the endoscopic images was 30 points.ResultsA total of 330 patients, comprising 181 in group A and 149 in group B, were enrolled. Three patients with HNSCC were detected in group A (1.7%) and in group B (2.0%; P = 1.000). Mean ± standard deviation (SD) examination times were 157 ± 71 s and 174 ± 109 s in groups A and B, respectively, (P = 0.073). Mean ± SD scores of the endoscopic images were 25.04 ± 5.47 points and 27.01 ± 4.35 points in groups A and B, respectively, (P < 0.001).ConclusionThe HNSCC detection rate based on the use of NBI on patients with ESCC did not improve after the training program for beginner endoscopists; however, endoscopic image quality improved significantly after the training program.
Effects of surgical targeting in laser interstitial thermal therapy for mesial temporal lobe epilepsy: A multicenter study of 234 patients
Authors: Wu Chengyuan , Jermakowicz Walter J. , Chakravorti Srijata , Cajigas Iahn , Sharan Ashwini D. , Jagid Jonathan R. , Matias Caio M. , Sperling Michael R. , Buckley Robert , Ko Andrew , Ojemann Jeffrey G. , Miller John W. , Youngerman Brett , Sheth Sameer A. , McKhann Guy M. , Laxton Adrian W. , Couture Daniel E. , Popli Gautam S. , Smith Alexander , Mehta Ashesh D. , Ho Allen L. , Halpern Casey H. , Englot Dario J. , Neimat Joseph S. , Konrad Peter E. , Neal Elliot , Vale Fernando L. , Holloway Kathryn L. , Air Ellen L. , Schwalb Jason , Dawant Benoit M. , D'Haese Pierre‐Francois 
Published: May 2019

AbstractObjectiveLaser interstitial thermal therapy (LITT) for mesial temporal lobe epilepsy (mTLE) has reported seizure freedom rates between 36% and 78% with at least 1 year of follow‐up. Unfortunately, the lack of robust methods capable of incorporating the inherent variability of patient anatomy, the variability of the ablated volumes, and clinical outcomes have limited three‐dimensional quantitative analysis of surgical targeting and its impact on seizure outcomes. We therefore aimed to leverage a novel image‐based methodology for normalizing surgical therapies across a large multicenter cohort to quantify the effects of surgical targeting on seizure outcomes in LITT for mTLE.MethodsThis multicenter, retrospective cohort study included 234 patients from 11 centers who underwent LITT for mTLE. To investigate therapy location, all ablation cavities were manually traced on postoperative magnetic resonance imaging (MRI), which were subsequently nonlinearly normalized to a common atlas space. The association of clinical variables and ablation location to seizure outcome was calculated using multivariate regression and Bayesian models, respectively.ResultsAblations including more anterior, medial, and inferior temporal lobe structures, which involved greater amygdalar volume, were more likely to be associated with Engel class I outcomes. At both 1 and 2 years after LITT, 58.0% achieved Engel I outcomes. A history of bilateral tonic‐clonic seizures decreased chances of Engel I outcome. Radiographic hippocampal sclerosis was not associated with seizure outcome.SignificanceLITT is a viable treatment for mTLE in patients who have been properly evaluated at a comprehensive epilepsy center. Consideration of surgical factors is imperative to the complete assessment of LITT. Based on our model, ablations must prioritize the amygdala and also include the hippocampal head, parahippocampal gyrus, and rhinal cortices to maximize chances of seizure freedom. Extending the ablation posteriorly has diminishing returns. Further work is necessary to refine this analysis and define the minimal zone of ablation necessary for seizure control.
Long‐term successful outcome of a Streptococcus equi subspecies equi brain abscess
Authors: Schott H. C. , Esser M. M. , Pirie C. G. , Pease A. P. , Patterson J. S. , Reed S. M. 
Published: May 2019

SummaryWe previously described successful treatment, including surgical drainage, of a Streptococcus equi subspecies equi brain abscess that caused severe neurological deficits in a 7‐year‐old Quarter Horse mare. This report details the long‐term successful outcome of the case, findings of a magnetic resonance imaging (MRI) study performed 14 years after surgery and necropsy findings 18 years after initial treatment. Despite persistent cerebral and midbrain lesions detected by MRI and at necropsy, the mare returned to serviceable function within a year of initial treatment and had a successful performance career for over 10 years until carpal arthritis prompted retirement. This case demonstrates that brain abscess in horses can be successfully managed by combined medical and surgical treatment.
Investigation of the anisotropic cyclic damage behavior of selective laser melted AISI 316L stainless steel
Authors: Stern Felix , Kleinhorst Jan , Tenkamp Jochen , Walther Frank 
Published: May 2019

AbstractThe additive manufacturing technique selective laser melting (SLM) is the most common process for metallic powders. The layer‐by‐layer process allows construction of components with high complex designs compared with conventional process routes. However, the orientation of parts related to the build platform and later to different loading conditions should be taken into account as the process‐induced microstructure and defects creating anisotropic mechanical behavior. To evaluate this influence of the building orientation as well as the process‐induced defects, different fatigue tests were performed on the SLM‐processed austenitic steel AISI 316 L (X2CrNiMo17‐12‐2). The distribution of the process‐induced porosity and, thus, the fatigue behavior is strongly related to the building direction, leading to a reduction of fatigue life for the tested 90° specimens of more than 90%.
The local market perception of firm risks during cross‐listing events
Authors: Schumann‐Foster Kathryn , Semaan Elias , Sono Hui 
Published: May 2019

AbstractWe examine the local investors’ perceptions on the relative idiosyncratic risks around cross‐listing events. We find that increases in relative firm‐specific risks around the listing date are temporary and small for Level I American depositary receipts (ADRs) while Level III ADRs have the most variations. For exchange‐listed ADRs from emerging markets, there is a significant decrease in the relative firm‐specific risk in the year prior to listing, which increases during the cross‐listing, while there are only significant increases in relative firm‐specific risks for developed market firms. We interpret these as evidences of negative relationship between firm opaqueness and relative firm‐specific risks.