bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of influencer marketing of food and a “protective” advertising disclosure on children's food intake
Authors: Coates Anna Elizabeth , Hardman Charlotte Alice , Halford Jason Christian Grovenor , Christiansen Paul , Boyland Emma Jane 
Published: June 2019

SummaryBackgroundChildren are active on social media and consequently are exposed to new and subtle forms of food marketing.ObjectivesTo examine whether exposure to a YouTube video featuring influencer marketing of an unhealthy snack affects children's ad libitum snack intake and whether inclusion of an advertising disclosure moderates this effect.MethodsIn a randomized between‐subjects design, 151 children (aged 9‐11 y; mean, 10.32 y ± 0.6) were exposed to influencer marketing of a non‐food product (n = 51), or an unhealthy snack with (n = 50) or without (n = 50) an advertising disclosure. Participants' ad libitum intake of the marketed snack and an alternative brand of the same snack was measured.ResultsChildren exposed to food marketing with (P < .001, d = 1.40) and without (P < .001, d = 1.07) a disclosure consumed more (kcals) of the marketed snack relative to the alternative; the control did not differ (.186, d = 0.45). Consumption of the alterative brand did not differ across conditions (.287, ηp2 = .02). Children who viewed food marketing with a disclosure (and not those without) consumed 41% more of the marketed snack (.004, ηp2 = .06), compared with control.ConclusionsInfluencer marketing increases children's immediate intake of the promoted snack relative to an alternative brand. Advertising disclosures may enhance the effect.
Impact of the e-prescribing system on the incidence and nature of drug-related problems in children in a Saudi hospital
Authors: AlAzmi Aeshah A , AlHamdan Hani , Ahmed Omaima , Tomlin Stephen , Rashed Asia N 
Published: June 2019

Abstract

Objectives
To determine the impact of a computerised physician order entry (CPOE) system on the drug-related problems’ (DRPs) incidence and characteristics in hospitalised children in a Saudi hospital, and to compare DRPs incidence pre-/post-CPOE implementation.

Methods
An observational study. DRPs were identified by pharmacists, reviewing children's (0-14 years) medical records on CPOE system, in paediatric wards and/or attending emergency department. DRPs preventability and severity were assessed.

Results
A total of 657 paediatric patients were included, with 235 (35.8%) experienced 328 DRPs, majority were preventable (99.7%, 327). Difference in DRP incidence pre- and post-CPOE implementation (44.8% versus 35.8%, P &lt; 0.01) was significant.

Conclusion
The CPOE system has significantly reduced DRPs incidence in children in the study hospital.
In‐situ synthesis of NaP zeolite doped with transition metals using fly ash
Authors: Zhang Yanan , Kang Wei , Han Hongjing , Wang Haiying , Chen Yanguang , Gong Xuzhong , Zhai Changxiu , Song Hua 
Published: June 2019

AbstractHere, a novel approach has been proposed to synthesize NaP zeolite adsorbents doped with transition metals (M‐NaP) using the Na2SiO3 and NaAlO2 compounds extracted from fly ash via activation and stage treatment. The preparation process of M‐NaP employed the in‐situ synthesis in combination with organic complexation method. The effects of the addition amounts and valence state of transition metals on the zeolite products were investigated. The crystalline phase, morphology, and particle size of M‐NaP were characterized using X‐ray diffractometry (XRD), Scanning electron microscopy (SEM), and Laser particle size analyzer (PSD). The doping process was investigated using X‐ray photoelectron spectroscopy (XPS) and Materials Studio. The adsorption performance of M‐NaP was tested by the adsorption of Zn2+. The optimal molar ratio of n(Al2O3)/n(M) was identified as 8:1 for Co–NaP, Ni–NaP, and Fe–NaP, compared with 6:1 for Ti–NaP. The influence of transition metals on adsorption was: Co–NaP > Ni–NaP > Ti–NaP > Fe‐NaP. Due to largest surface area of Co–NaP (162.5 m2/g, five times than that of NaP‐RAW), the maximum removal rate of Zn2+ was above 99.50% at 25°C. The existence state of transition metals in M‐NaP primarily included: isomorphous substitution and balance of the skeletal charge, with the latter in majority. The simulation of Materials Studio indicates that Si at T4 was first substituted and then, Si at T3 opposite T4 was replaced when the replacement of Si in different sites occurred.
Pride and anxiety in online learning environments: Achievement emotions as mediators between learners' characteristics and learning outcomes
Authors: Heckel Christian , Ringeisen Tobias 
Published: June 2019

AbstractThe current study validated the proposed structure of relationships among outcome‐related achievement emotions (pride and anxiety), their cognitive predictors (appraisals und online‐learning‐related self‐efficacy), and learning outcomes (competence gain and satisfaction) in the context of online learning in higher education. On the basis of a sample of 220 university students, we applied structural equation modeling. We found that high self‐efficacy was related to greater perceived control, which was positively associated with interest in online learning. Self‐efficacy showed positive relations with pride and negative relations with anxiety. Interest was positively associated with pride, competence gain, and satisfaction. Both outcomes also showed direct positive relations with pride, whereas anxiety was negatively associated with satisfaction only. Furthermore, three substantial indirect effects of self‐efficacy on the two outcomes were revealed. The findings supported the role of anxiety and pride as mediators between cognitions and learning outcomes although also direct relationships between interest and learning outcomes were observed.
The effectiveness of aerobic exercise for hypertensive population: A systematic review and meta‐analysis
Authors: Cao Liujiao , Li Xiuxia , Yan Peijing , Wang Xiaoqin , Li Meixuan , Li Rui , Shi Xiue , Liu Xingrong , Yang Kehu 
Published: June 2019

AbstractThe study aims to evaluate the effectiveness of different durations of aerobic exercise on hypertensive patients. Four electronic databases (PubMed, Embase, Cochrane Library, and Web of Science) were searched from their inception until July 2018. English publications and randomized controlled trials involving aerobic exercise treatment for hypertensive population were included. Two reviewers independently extracted the data. The Cochrane's Risk of Bias tool was used to assess the quality of included studies. In this systematic review, a total of 14 articles were included, involving 860 participants. The quality of the included studies ranged from moderate to high. The results of the meta‐analysis showed that compared with the control group, significant effects of aerobic exercise were observed on reducing systolic blood pressure (SBP) (mean difference [MD] = −12.26 mm Hg, 95% confidence interval [CI] = −15.17 to −9.34, P < 0.05), diastolic blood pressure (DBP; MD = −6.12 mm Hg, 95% CI = −7.76 to −4.48, P < 0.05), and heart rate (MD = −4.96 bpm, 95% CI = −6.46 to −3.43, P < 0.05). In addition, significant reductions were observed in ambulatory DBP (MD = −4.90 mm Hg, 95% CI = −8.55 to −1.25, P < 0.05) and ambulatory SBP (MD = −8.77mm Hg, 95% CI = −13.97 to −3.57, P < 0.05). Therefore, aerobic exercise might be an effective treatment for blood pressure improvement in hypertensive patients. However, the effectiveness between the duration of different treatment needs to be well‐designed and rigorous studies will be required to verify the dataset.
Awareness of Beers Criteria and knowledge of potentially inappropriate medications among community pharmacists in the Klang Valley, Malaysia
Authors: Foong Ryan T.K. , Sellappans Renukha , Loo Jason S.E. 
Published: June 2019

AbstractBackgroundPotentially inappropriate medications (PIMs) in older adults are detrimental to both clinical outcomes and health care costs, with their prominence set to increase in tandem with a fast‐growing ageing population. Beers Criteria is one of the most commonly used guidelines that lists specific PIMs. Community pharmacists would therefore benefit from knowledge of Beers Criteria in detecting PIMs in primary care. This study therefore investigates the awareness of Beers Criteria and knowledge of PIMs among community pharmacists in the Klang Valley, Malaysia.MethodsThe study was conducted using a self‐administered questionnaire. Knowledge of PIMs was assessed using 10 clinical vignettes based on the 2015 Beers Criteria. Practice behaviour towards older customers was assessed using 10 items with a 5‐point Likert scale. Descriptive and inferential statistics were used to analyse the data.ResultsA total of 277 community pharmacists participated in the study. Only 27.1% of the pharmacists were aware of Beers Criteria, and of these, only 37.3% were aware of the latest 2015 update. The respondents demonstrated moderate knowledge of PIMs with a mean total score of 5.46 ± 1.89 out of a maximum of 10. Pharmacists who were aware of Beers Criteria had significantly higher scores (6.31 vs 5.14, P < .001). Only a small proportion of pharmacists (17.0%) regularly used Beers Criteria in practice. However, most pharmacists reported good practices when dealing with older customers in terms of asking relevant questions, considering age, referring to other resources, and regularly updating their knowledge through continuous professional development.ConclusionAwareness of Beers Criteria remains low among community pharmacists in Malaysia. Pharmacists who are aware of Beers Criteria have improved knowledge regarding PIMs in the older adults. There is a need to increase the awareness and use of Beers Criteria among community pharmacists.
Comparison of a novel wound dressing vs current clinical practice after laser resurfacing
Authors: Yeh Lindsey C. , Gonzalez Noelani , Goldberg David J. 
Published: June 2019

AbstractBackgroundThere are many postprocedure skin care options, but no consensus on the best formulation to optimize healing. Silicone gels have only been used to treat keloids and hypertrophic scars and typically applied after the wound has healed. This study compared the healing response after fractional ablative erbium laser resurfacing with a petrolatum‐based ointment and a silicone gel.MethodsA randomized, open‐label, split‐face study was performed. Ten subjects underwent Erbium:YAG (Sciton) fractional laser resurfacing. Patients were randomized to apply a petrolatum‐based gel or a silicone gel (Stratacel®; Stratpharma) on either the right or left side of the face. Subjects applied the products twice a day for 7 days and were evaluated in person 7, 30, and 60 days postprocedure. Subjects reported on the overall general aesthetic outcome, perceived pain, itch, and tightness via questionnaires using the Global Aesthetic Improvement Scale and the Wrinkle Severity Rating Scale (WSRS).ResultsAll subjects healed without complications. By day 60, there was no difference in signs and symptoms of healing between the two different dressing approaches. However, patients treated with the silicone gel had less post‐treatment erythema and hyperpigmentation.ConclusionsA novel silicone gel resulted in reduced signs of erythema and hyperpigmentation postprocedure, without an increase in adverse events. Additionally, the silicone gel dries to form a thin, full contact film and can be covered with sunscreen or cosmetics once dry. This new silicone gel presents a good option for postprocedure care after ablative fractional laser resurfacing.
Becoming a First‐Time Grandparent and Subjective Well‐Being: A Fixed Effects Approach
Authors: Sheppard Paula , Monden Christiaan 
Published: June 2019

Objective: In this study, the authors examined how individuals are affected by the change in status to grandparenthood for the first time.Background: Being a grandparent, especially an active and involved grandparent, is positively linked to the well‐being of individuals with grandchildren; however, little is known about how becoming a grandparent affects well‐being.Method: Longitudinal data pooled from 15 countries in Europe (Survey of Health, Ageing and Retirement in Europe;
http://www.share‐project.org) are used to analyze if becoming a grandparent is associated with three measures of subjective well‐being. The authors use fixed effects models to account for unobserved heterogeneity.Results: Becoming a first‐time grandparent is associated with fewer depressive symptoms among women, although there is no evidence for an effect on subjective life expectancy or life satisfaction. For men, there is no evidence for an impact on any outcome tested, although there is an association with increased subjective life expectancy conditional on employment status only if men were employed when transitioning to grandparenthood. The results provide no evidence that actively looking after the grandchild is important for either gender.Conclusion: These results suggest that, at least for women, it is the life transition itself that impacts on some aspects of well‐being rather than active grandchild care. More research is needed to verify these findings in other contexts and for longer periods of time.
Role of salivary transcriptomics as potential biomarkers in oral cancer: A systematic review
Authors: Patil Shankargouda , Arakeri Gururaj , Alamir Abdul Wahab H. , Awan Kamran Habib , Baeshen Hosam , Ferrari Marco , Patil Shekar , Fonseca Felipe Paiva , Brennan Peter A. 
Published: June 2019

AbstractIntroductionTranscriptomes in saliva can be used as potential biomarkers for both diagnostic and response to treatment in oral squamous cell carcinoma (OSCC). In this review, we explored their application in this increasingly common disease.Materials and methodsPubMed, EMBASE, Scopus, Web of Science and grey literature from January 1990 to May 2017 were searched. Two independent reviewers performed the study selection according to eligibility criteria.ResultsA total of nine studies were included. Three studies showed increased expression of DUSP1, IL8, IL1B, OAZ1, SAT1, S100P and two showed increased expression of miRNA‐31 among study groups compared to normal healthy controls. The sensitivity ranged from 14% to 100%, while the specificity ranged from 38% to 100%. miRNA‐27b had the highest AUC (write in full) of 0.9643 and DUSP1 had the minimum AUC of 0.41.ConclusionSalivary transcriptomics may play an effective role as a robust and non‐invasive biomarker sighting tool for the diagnosis and management of OSCC.
Teen Dating Violence Perpetration: Protective Factor Trajectories from Middle to High School among Adolescents
Authors: Espelage Dorothy L. , Leemis Ruth W. , Niolon Phyllis Holditch , Kearns Megan , Basile Kathleen C. , Davis Jordan P. 
Published: June 2019

Protecting adolescents from the risk of teen dating violence (TDV) perpetration is critical to enhancing prevention efforts. This study examined longitudinal trajectories of four protective factors (i.e., empathy, social support, parental monitoring, and school belonging) across adolescence in relation to four TDV types (i.e., verbal, relational, physical, and sexual). Adolescents (n = 1,668) who reported being in a relationship or dating during high school completed self‐report measures from middle through high school. Results indicated that all protective factors differentiated between TDV perpetrators and nonperpetrators, although these trajectories varied for boys and for girls and across the different types of TDV. Overall, youth who did not perpetrate TDV in high school generally displayed higher protective factors across the TDV perpetration types.
Planning, Development, and Implementation of a University‐Led, Low‐Cost Employee Wellness Program in a preK‐12th‐Grade Public School District
Authors: Lloyd Lisa K. , Schmidt Eric A. , Swearingen Carolyn C. , Cavanaugh Allison C. 
Published: June 2019

ABSTRACTBACKGROUNDA healthy preK‐12th‐grade school environment is critical to student well‐being and success. As role models, school employees play a significant part in creating a healthy environment. Research suggests that employee wellness programs (EWPs) may help school employees adopt healthier lifestyles and, therefore, be healthier, more productive, and serve as healthy role models for students. This article describes the process by which a school district in central Texas partnered with a local university to plan, develop, and implement an affordable EWP.METHODSA university‐led leadership team sought input from employees, including administrators, and conducted a 4‐week trial. These resulted in an EWP that provided health risk appraisals, fitness testing, group exercise classes, education seminars, online wellness resources, and blood draws/analysis.RESULTSDuring the first 4 years, membership ranged from 107 to 384 (10–37%), and the annual cost of the program ranged from $49 to $116 per participating employee.CONCLUSIONSUniversity‐led EWP programs can support, at a low cost, the health of school employees. Despite low employee engagement, need was demonstrated and feedback was positive. Challenges identified include time demands and lack of principals' support. Future considerations include targeting principals, utilizing the Human Resources Office, and strategically building a culture of health.
School‐Based Mental Health Promotion and Prevention Program “Turn 2 Us” Reduces Mental Health Risk Behaviors in Urban, Minority Youth
Authors: Raval Gauri , Montañez Evelyn , Meyer Dodi , Berger‐Jenkins Evelyn 
Published: June 2019

ABSTRACTBACKGROUNDTurn 2 Us (T2U) is an elementary school‐based mental health promotion and prevention program in New York City. It targets fourth‐ and fifth‐grade students at risk for social/emotional and behavioral problems and provides a range of services to students, staff, and parents. The purpose of this study is to determine if T2U decreases internalizing and externalizing behaviors in participating students.METHODSTeachers measured students' symptoms before and after participation using the strengths and difficulties questionnaire (SDQ). Change in the total SDQ score was analyzed using Wilcoxon rank‐sum nonparametric testing. We assessed the effects of covariates on the score change with linear regression models.RESULTSThe 185 unique students who participated in the intervention showed a significant improvement in total SDQ score (Z = −4.107, p < .001). Students who were at higher risk prior to the intervention showed greatest improvement in behaviors. None of the covariates assessed affected the change in SDQ score. Regression models showed that higher initial SDQ scores predicted higher post‐intervention SDQ scores (β = 0.681, p < .001).CONCLUSIONT2U significantly decreased internalizing and externalizing behaviors in participating students, with the greatest impact for highest risk students. This study helps validate T2U's unique and comprehensive approach.
‘Whatever decision you make it will be the right one’: A parent's reflection on difficult decision‐making in premature birth
Authors: O'Neill Jenny 
Published: June 2019

AbstractIn 2007, our daughter Lily was born prematurely. My husband and I were faced with a very difficult decision about the level of intervention for her, a decision that had to be made in an emergency situation under the pressure of time. As a paediatric nurse I had more knowledge about prematurity than most parents, and it was certainly enough to appreciate the fragility of babies born early, and their uncertain and often complicated path through neonatal intensive care. What I didn't fully appreciate was the key role of health professionals, not only in providing care, but in supporting difficult decision‐making. In the years since Lily's birth I've also reflected on the power of health professionals to shape, or reshape, the narrative of premature birth which is pivotal in the long‐term psychological trajectory of parents.
The impact of prematurity on postnatal growth of different renal compartments
Authors: Li Joan , Guandalini Michael , Mcinnes Helena , Kandasamy Yogavijayan , Trnka Peter , Moritz Karen 
Published: June 2019

ABSTRACTAimIn humans, nephrogenesis ceases before birth, but the renal medulla compartment continues to develop after birth. We aim to evaluate the relative growth of different renal compartments in preterm babies compared with age‐matched term babies, and explore the impact of premature birth on postnatal renal maturation, remodelling and possible long‐term implications.MethodsThis retrospective study compared the renal ultrasonographic images between preterm babies and term infants. Ultrasound images were obtained at 32 weeks (preterm), 37 weeks and at 6 months of age. Kidney volume, length, renal cortex and medulla thickness were measured and compared between preterm and term babies.ResultsPreterm babies were lighter in body weight and shorter for crown‐heel length at age‐matched 37 weeks. All kidney growth parameters were also smaller compared with term babies. However, by 6 months of age kidney volume and length measurements were no longer significantly different between the two groups though preterm babies were still significantly lighter and shorter. The catch‐up of the overall kidney growth in preterm babies was mainly attributed to the hypertrophic growth of the renal cortex while the postnatal renal medulla growth was disrupted. This trend continued as the renal cortical thickness became significantly larger while the medulla became smaller in preterm babies at 6 months of age, compared with age‐matched term baby.ConclusionsIn preterm babies, the renal cortical region undergoes accelerated growth after birth while the renal medulla growth lags behind. Further investigations will be necessary to determine whether this has a negative impact on renal function later in life.
Redox interference in nitrogen status via oxidative stress is mediated by 2‐oxoglutarate in cyanobacteria
Authors: Robles‐Rengel Rocío , Florencio Francisco J. , Muro‐Pastor M. Isabel 
Published: June 2019

Summary

Reactive oxygen species (ROS) are generated naturally in photosynthetic organisms by respiration and photosynthesis. Therefore, detoxification of these compounds, avoiding oxidative stress, is essential for proper cell function. In cyanobacteria, some observations point to a crosstalk between ROS homeostasis, in particular hydrogen peroxide, and nitrogen metabolism by a mechanism independent of known redox regulators.

Using glutamine synthetase (GS), a finely regulated enzyme essential for nitrogen assimilation, as a tool, we were able to monitor nitrogen metabolism in relation to oxidative stress.

We show that hydrogen peroxide clearly alters the expression of different genes related to nitrogen metabolism, both in the wild‐type strain of the cyanobacterium Synechocystis sp. PCC 6803 and in a mutant strain lacking the catalase‐peroxidase encoded by the katG gene and therefore highly sensitive to oxidative stress. As cyanobacteria perceive nitrogen status by sensing intracellular 2‐oxoglutarate (2‐OG) concentrations, the hydrogen peroxide effect was analysed under different nitrogen conditions in the wild‐type, the ∆katG strain and in a strain able to transport 2‐OG.

The results obtained demonstrate that hydrogen peroxide interferes with signalling of cellular carbon : nitrogen status by decreasing the intracellular concentrations of 2‐OG and hence altering the function of the 2‐OG‐sensing global nitrogen regulator NtcA.