bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Performance and Environmentally‐Friendly Bulk‐Wave‐Acoustofluidic Devices Driven by Lead‐Free Piezoelectric Materials
Authors: Qiu Wei 
Published: November 2024

AbstractBulk‐wave‐acoustofluidic devices provide strong acoustic fields and high device efficiency, thereby offering high‐throughput capability when processing biological samples. Such devices are typically driven by lead zirconate titanate (PZT) transducers, which contain a high content of lead, inevitably resulting in environmental and biocompatibility issues. Replacing PZT with lead‐free piezoelectric materials in various ultrasonic devices is considered challenging mainly due to the inferior piezoelectric properties lead‐free materials possess compared to those of PZT. In this study, through both experiments and numerical simulations, it is demonstrated that the performance of the bulk‐wave‐acoustofluidic devices driven by (Bi,Na)TiO3‐BaTiO3‐(Bi,Na)(Mn,Nb)O3 (BNT‐BT‐BNMN) can match that of PZT‐driven devices at low power and is superior at intermediate power. It is found that the low acoustic impedance and the weak transverse mode in BNT‐BT‐BNMN compensate for the inferior piezoelectric properties at low power. The fact that the BNT‐BT‐BNMN devices outperform at intermediate power is consistent with the superior performance of the Mn‐doped BNT‐based piezoelectric materials compared to PZT at high power. Perfect focusing on 5‐‐diameter polystyrene particles at a flow rate of up to 10 mL min−1 is achieved using the BNT‐BT‐BNMN device at input power of 1 W.
Magnetically Responsive Enzyme and Hydrogen‐Bonded Organic Framework Biocomposites for Biosensing
Authors: Carraro Francesco , Aghito Margherita , Dal Zilio Simone , Wolinski Heimo , Doonan Christian J. , Nidetzky Bernd , Falcaro Paolo 
Published: November 2024

AbstractThe one‐pot synthesis of multicomponent hydrogen‐bonded organic framework (HOF) biocomposites is reported. The co‐immoblization of enzymes and magnetic nanoparticles (MNPs) into the HOF crystals yielded biocatalysts (MNPs‐enzyme@BioHOF‐1) with dynamic localization properties. Using a permanent magnet, it is possible to separate the MNPs‐enzyme@BioHOF‐1 particles from a solution. Catalase (CAT) and glucose oxidase (GOx) show increased retention of their activity when coimmobilized with MNPs. MNPs‐GOx@BioHOF‐1 biocomposites are used to prepare a proof‐of‐concept glucose microfluidic biosensor, where a magnet allow to position and keep in place the biocomposite inside a microfluidic chip. The magnetic response of these biocatalysts can pave the way for new applications for the emerging HOF biocomposites.
Effect of Ni‐Doping on the Optical, Structural, and Electrochemical Properties of Ag29 Nanoclusters
Authors: Ahmed Abdullah A. A. , Havenridge Shana , Sahoo Koustav , Thapa Loknath , Baksi Ananya , Clever Guido H. , Noei Heshmat , Kohantorabi Mona , Stierle Andreas , Raj C. Retna , Parak Wolfgang J. , Aikens Christine M. , Chakraborty Indranath 
Published: November 2024

AbstractAtomically precise metal nanoclusters (NCs) can be compositionally controlled at the single‐atom level, but understanding structure‐property correlations is required for tailoring specific optical properties. Here, the impact of Ni atom doping on the optical, structural, and electrochemical properties of atomically precise 1,3‐benzene dithiol (BDT) protected Ag29 NCs is studied. The Ni‐doped Ag29 (NiAg28(BDT)12) NCs, are synthesized using a co‐reduction method and characterized using electrospray ionization mass spectrometry (ESI MS), ion mobility spectrometry (IMS), and X‐ray photoelectron spectroscopy (XPS). Only a single Ni atom doping can be achieved despite changing the precursor concentration. Ni doping in Ag29 NCs exhibits enhanced thermal stability, and electrocatalytic oxygen evolution reaction (OER) compared to the parent NCs. Density functional theory (DFT) calculations predict the geometry and optical properties of the parent and NiAg28(BDT)12 NCs. DFT is also used to study the systematic single‐atom doping effect of metals such as Au, Cu, and Pt into Ag29 NCs and suggests that with Ni and Pt, the d atomic orbitals contribute to creating superatomic orbitals, which is not seen with other dopants or the parent cluster. The emission mechanism is dominated by a charge transfer from the ligands into the Ag core cluster regardless of the dopant.
Interplay Between Calcination Temperature and Alkaline Oxygen Evolution of Electrospun High‐Entropy (Cr1/5Mn1/5Fe1/5Co1/5Ni1/5)3O4 Nanofibers
Authors: Vezzù Keti , Triolo Claudia , Moulaee Kaveh , Pagot Gioele , Ponti Alessandro , Pinna Nicola , Neri Giovanni , Santangelo Saveria , Di Noto Vito 
Published: November 2024

AbstractSpinel‐structured transition metal (TM) oxides have shown great potential as a sustainable alternative to platinum group metal‐based electrocatalysts. Among them, high‐entropy oxides (HEOs) with multiple TM‐cation sites are suitable for engineering octahedral redox‐active centers to enhance the catalyst reactivity. This paper reports on the preparation of electrospun (Cr1/5Mn1/5Fe1/5Co1/5Ni1/5)3O4 nanofibers (NFs) and their evaluation as electrocatalysts. Its main aim is to unveil the nanostructural features that play a key role in the alkaline oxygen evolution reaction. Differing calcination temperature (300−800 °C) and duration (2 or 4 h) leads to different morphology of the NFs, crystallinity of the oxide, density of defects, and cation distribution in the lattice, which reflect in different electrocatalytic behaviors. The best performance (overpotential and Tafel slope at 10 mA cm−2: 325 mV and 40 mV dec−1, respectively) pertains to the NFs calcined at 400 °C for 2 h. To gain a deeper understanding of their electrocatalytic properties, the pristine NFs are investigated by a combination of analytical techniques. In particular, broadband electric spectroscopy reveals that the mobility of oxygen vacancies in the best electrocatalyst is associated to very fast local dielectric relaxations of metal coordination octahedral geometries and experimentally demonstrates the key role of O‐deficient octahedra.
Dynamically Reconstructed Fe‐CoOOH Semi‐Crystalline Electrocatalyst for Efficient Oxygen Evolution Reaction
Authors: Qayum Abdul , Harrath Karim , Li Rui , Woldu Abebe Reda , Chu Paul K. , Hu Liangsheng , Lu Fushen , Yao Xiangdong 
Published: November 2024

AbstractThe development of robust and efficient electrocatalysts for the oxygen evolution reaction (OER) has been the main focus of water electrolysis but remains a great challenge. Here, the synthesis of a highly active and ultra‐stable Fe‐CoOOH electrocatalyst is reported by steering raw cobalt foam via an in situ solution combustion method assisted by a galvanic replacement reaction and subsequent electrochemical reconstruction of the CoFeOx pre‐catalyst. In/ex situ electrochemical analysis and physicochemical characterizations show that the CoFeOx undergoes quick chemical and slow morphological reconstruction to Fe‐CoOOH nanosheets. The Fe‐CoOOH possesses a semi‐crystalline nature with distinct short‐range ordering and outstanding OER activity with overpotentials as low as 271 and 291 mV at current densities of 500 and 1,000 mA cm−2, respectively. The remarkable stability under 1,000 mA cm−2 for at least 700 h is achieved. Theoretical calculations confirm the crucial role of Fe doping in facilitating surface reconstruction, enhancing OER activity, and improving the stability of the Fe‐CoOOH. Comparative analysis with other transition metals doping reveals the unique ability of Fe to adsorb onto the CoOOH surface, thereby modulating the electronic density and facilitating faster adsorption of reaction intermediates. This work represents valuable insights into the surface reconstruction and doping processes.
Microsensor‐Internalized Fibers as Autonomously Controllable Soft Actuators
Authors: Lee Youngbin , Won Joonhee , Kim Dong‐Yeong , Park Seongjun 
Published: November 2024

AbstractDespite their strengths in flexibility and miniaturization, the stable operation of soft actuators under ever‐changing environmental and biological conditions is hindered by the lack of applicable methods using internal sensors to detect unintentional stimuli. Here, the integration of a microscale driving source and sensors in a single fiber via thermal drawing is presented as a strategy to scalably produce autonomously responsive, feedback‐controllable soft actuators. The regulation of the input electrothermal stimuli via a closed loop control system that is based on completely coupled internal sensory components enables multimodal actuation of fiber‐based actuators, which is further demonstrated through preservation of actuating conditions, actuation of selected devices in their bundles, and modulation of motion characteristics. The approach to manufacturing autonomously controllable soft actuators can expand applications of soft actuators in kaleidoscopic biomedical and bioengineering fields for transportation, robotics, and prosthetics.
The Molecular Additive N‐Acetyl‐L‐Phenylalanine Delays the Crystallization and Suppresses the Phase Impurity for Achieving Triple‐Cation Perovskite Solar Cells with Efficiency Over 25%
Authors: Ding Yang , Lu Siyuan , Chang Jianhui , Feng Erming , Li Hengyue , Long Caoyu , Yang Yingguo , Yi Chenyi , Zheng Zijian , Ding Liming , Yang Junliang 
Published: November 2024

AbstractThe crystallization process plays an important role in the formation of high‐quality perovskite film for achieving efficient perovskite solar cells (PSCs), especially in the formation of mixed‐cation perovskite film, as there are normally more phase impurities than in pure CH(NH2)2PbI3 (FAPbI3) film. Herein, a molecular additive strategy, i.e., introducing non‐planar molecule N‐acetyl‐L‐phenylalanine (APO) into the lead iodide (PbI2) precursor solution, is proposed to modulate crystallization kinetics and inhibit the generation of phase impurities of metastable pretreated perovskite film. The delayed crystallization process promotes a sufficient reaction between organic salts solution and inorganic Pb‐I framework, and perovskite phase decomposition is prevented by forming strong hydrogen bonds between ─NH and I, resulting in the formation of uniform film with large‐size crystal grains and high‐purity crystalline phase. Ultimately, the target PSC devices achieve an impressive power conversion efficiency (PCE) of 25.05%, which is among the highest values of triple‐cation (FAMACs) PSCs. Meanwhile, PSC modules with 10.8 cm2 obtain a PCE of 20.35%. Furthermore, the unencapsulated PSCs retain 94% of the initial efficiency after 40 days of storage under ambient conditions with 20% RH and also yield superior operational stability under light soaking at maximum power point tracking (MPPT) in nitrogen (N2) atmosphere.
A New Method for Regression Analysis of Case–Cohort Interval‐Censored Failure Time Data
Authors: Jia Ruobing , Lou Yichen , Sun Jianguo , Wang Peijie 
Published: November 2024

ABSTRACTThe case–cohort design is widely used as a way of reducing costs when the disease incidence is low and covariates are expensive to measure. In this paper, we consider regression analysis of interval‐censored failure time data arising from the case–cohort design under a class of semiparametric transformation models. Although some methods have been proposed for the situation, they only make use of the information on the subjects in the subcohort and thus can be less efficient. To address this, we propose a class of linear inverse probability weighted estimators that make use of the information on all subjects. Furthermore, a method is provided to determine the optimal weights, and the proposed estimator is shown to be consistent and asymptotically normal. A simulation study is performed and indicates that the proposed method works well for practical situations, and it is illustrated by using the data arising from an Alzheimer's disease study.
Touch, light, wounding: how anaesthetics affect plant sensing abilities
Authors: Pavlovič Andrej 
Published: November 2024

Abstract
Key message
Anaesthetics affect not only humans and animals but also plants. Plants exposed to certain anaesthetics lose their ability to respond adequately to various stimuli such as touch, injury or light. Available results indicate that anaesthetics modulate ion channel activities in plants, e.g. Ca2+ influx.

Abstract
The word anaesthesia means loss of sensation. Plants, as all living creatures, can also sense their environment and they are susceptible to anaesthesia. Although some anaesthetics are often known as drugs with well-defined target to their animal/human receptors, some other are promiscuous in their binding. Both have effects on plants. Application of general volatile anaesthetics (GVAs) inhibits plant responses to different stimuli but also induces strong cellular response. Of particular interest is the ability of GVAs inhibit long-distance electrical and Ca2+ signalling probably through inhibition of GLUTAMATE RECEPTOR-LIKE proteins (GLRs), the effect which is surprisingly very similar to inhibition of nerve impulse transmission in animals or human. However, GVAs act also as a stressor for plants and can induce their own Ca2+ signature, which strongly reprograms gene expression . Down-regulation of genes encoding enzymes of chlorophyll biosynthesis and pigment-protein complexes are responsible for inhibited de-etiolation and photomorphogenesis. Vesicle trafficking, germination, and circumnutation movement of climbing plants are also strongly inhibited. On the other hand, other cellular processes can be upregulated, for example, heat shock response and generation of reactive oxygen species (ROS). Upregulation of stress response by GVAs results in preconditioning/priming and can be helpful to withstand abiotic stresses in plants. Thus, anaesthetic drugs may become a useful tool for scientists studying plant responses to environmental stimuli.
Efficacy and safety of patiromer for non-dialysis and dialysis patients with hyperkalemia: the randomized, placebo-controlled and long-term study
Authors: Kashihara Naoki , Kumeda Yasuro , Higashino Yorihiko , Maeda Yoshitaka , Kaneko Yoko , Kanai Hidetoshi , Taniguchi Yuko , Ishii Takayuki , Tomioka Yusuke 
Published: November 2024

Abstract
Background
The objectives of this phase two study are to investigate the efficacy of two starting doses of 8.4 g and 16.8 g and evaluate the long-term safety of patiromer in Japanese patients with hyperkalemia.

Methods
This study comprised three cohorts; non-dialysis patients with baseline serum potassium (sK) level of 5.1 to < 6.0 mmol/L (NDC1); 6.0 to < 6.5 mmol/L (NDC2); dialysis patients with baseline sK level of 5.5 to < 6.5 mmol/L (DC). The study design was one-week, randomized, double-blind, placebo-controlled, and open label extension for one year in NDC1, open label during the study in NDC2 and DC. Patients were randomly assigned to patiromer 8.4 g, 16.8 g or placebo in NDC1, 8.4 g or 16.8 g in NDC2 and DC. Dose was adjusted up to 25.2 g according to the titration algorism in open label period.

Results
A total of 185 patients were randomized (NDC1:153, NDC2:10, and DC:22). The primary endpoint of the change in least squares mean sK levels at Week 1 in NDC1 was  – 0.55,  – 0.77 and  – 0.10 mmol/L for the 8.4 g, 16.8 g and placebo group (P < 0.001 for the patiromer group vs the placebo group). In all cohorts for each patiromer group, more than 80% of patients achieved normal sK at Week 5. There was no severe treatment-related adverse event.

Conclusion
Treatment with patiromer was effective in lowering and maintaining target sK levels, also well tolerated for one year in Japanese patients with hyperkalemia.
Going Mental: Why Physicalism Should Not Posit Inscrutable Properties
Authors: Ryan Liam D. 
Published: November 2024

AbstractSome philosophers argue that mental properties are ontologically distinct from physical properties and that, therefore, physicalism ought to be rejected. There are philosophers who feel the force of this challenge but who wish to maintain their physicalism. They suggest that mentality is grounded in inscrutable properties or ‘incrutables’: properties that are not revealed through physical enquiry but that do not violate physicalism. Our analysis reveals that appealing to inscrutables is not a successful strategy for these physicalists, for the following reasons: first, inscrutables likely do violate the conditions of physicalism; second, inscrutables lend greater support to panpsychism than physicalism; third, there is good reason to be agnostic as to whether or not inscrutables count as physical properties. Each of these reasons undermines the physicalist’s purpose in positing inscrutables. If one wishes to remain a physicalist, they ought to direct their philosophical analysis and energies toward revisiting and defeasing the arguments that purport to show that mental properties are ontologically distinct from physical properties.
Decreased mitochondrial transcription factor A and mitochondrial DNA copy number promote cyclin-dependent kinase inhibitor 1A expression and reduce tumorigenic properties of colorectal cancer cells
Authors: Buchwaldt Jessika , Fritsch Tania , Hartmann Monika , Witzel Hagen Roland , Kloth Michael , Roth Wilfried , Tagscherer Katrin E. , Hartmann Nils 
Published: November 2024

Abstract
Purpose
Colorectal cancer is one of the most common and deadliest cancer types worldwide. In the last years, changes in the mitochondrial DNA (mtDNA) copy number have been described to correlate with the prognostic outcome for colorectal cancer patients by impacting different tumorigenic properties. One key regulator of mtDNA is the mitochondrial transcription factor A (TFAM) that acts as a limiting factor of mtDNA copy number. Here, we investigated the effect of TFAM deficiency on mtDNA and tumorigenic properties in the human colorectal cancer cell line SW480.

Methods
TFAM expression was stably downregulated in the colorectal cancer cell line SW480 using the CRISPR-Cas9 approach. To dissect the molecular alterations induced by deletion of TFAM, RNA sequencing and gene set enrichment analysis was performed on TFAM-wild-type and TFAM-deficient SW480 cells. Functional consequences of TFAM downregulation were assessed in cellular assays.

Results
We showed that TFAM deficiency leads to decreased mtDNA copy number and reduced expression of mtDNA-encoded genes. TFAM-deficient cells also revealed higher activity of senescence-associated β-galactosidase and decreased cell growth parameters. Moreover, RNA sequencing showed that the expression of cyclin dependent kinase inhibitor 1A (CDKN1A/p21) is significantly increased in TFAM-deficient cells.

Conclusion
Our results suggest that TFAM-induced changes of the mitochondrial genome lead to upregulated CDKN1A/p21 expression in colorectal cancer cells identifying p21 as a new possible linker between mitochondria and nucleus.
Closed-loop control of a directed energy deposition process for repair applications
Authors: Touzé Stéphane , Navarro Valero Carolina , Rückert Guillaume , Hascoët Jean-Yves 
Published: November 2024

AbstractAdditive manufacturing processes of the directed energy deposition family such as laser metal deposition or wire arc additive manufacturing offer great control and improved metallurgical properties over traditional processes such as casting. They are very promising for many industrial applications such as the fabrication of intricate parts with high-performance alloys as well as repair applications. However, these processes are generally very sensitive to process conditions, yet are most often operated in open loop. In this study, a closed-loop controller with a suitable error criteria based on 3D scanning data in-between layers is implemented. It is applied to various repair samples made of 316L stainless steel and Inconel 625 materials. The results show that the controller can compensate for suboptimal operating points and in-process deviations while maintaining satisfactory metallurgical and mechanical properties.
China’s role in the EU’s search for strategic autonomy: nonhegemonic power relations during world order transition
Authors: Huang Jing 
Published: November 2024

Abstract
By applying an analysis framework related to historical structure developed by Robert W. Cox, the article attempts to explore China’s role in the European Union (EU)’s search for strategic autonomy (SA). Moreover, it aims to understand big power relations during world order transition in a broader sense. The article argues that EU-SA is the EU’s strategy to navigate through the transition in global order and to maintain its values and interests in the upcoming order. In other words, EU-SA is a hegemonic game both inside and beyond the EU. That is how China is related to EU-SA. EU-SA can be evaluated as ideas, institutions and capabilities and China has been involved in EU-SA on three interrelated levels: social forces, forms of state and global order. The author provides a comprehensive summary of several features of China–Europe relations as well as nonhegemonic power relations during world order transition.
The semantics of Afro-Brazilian spirits: Applying Davidson on prior and passing theories
Authors: Engler Steven , Gardiner Mark Q. 
Published: November 2024

Abstract
Based on fieldwork with two related Afro-Brazilian religions, Umbanda and Quimbanda, this article explores the value of Donald Davidson’s semantic theory for making sense of ethnographic fieldwork. Specifically, we look at the role of scriptedness in communication, including religious ritual. We first clarify the role of social externalities in Davidson’s view of communicative interpretation, which is broader than his initial framework of radical interpretation. We then offer an account of what constitutes communicative and interpretational success, by drawing on Davidson’s account of prior and passing theory. Prior theories are interpreters’ initial hypothetical frameworks, ranging from general (e.g., the rational, intentional nature of self and other, and a shared perceivable world) to local (e.g., assumptions about cultural, social, and institutional contexts). Passing theories are tactical, on-the-fly modifications that we hypothesize in order to get mutual understanding back on track. We introduce the concept of ‘semantic reduction’ to operationalize the view that specific, local social externalities provide clues that help keep interpretation on track. In the case of religious ethnography, these include ritual, doctrinal, narrative, symbolic, material, temporal, and spatial frames that constrain the generation of passing theories. Examples from fieldwork illustrate the potential value of our appeal to Davidson’s ideas.
Macau Scientific Satellite‐1 Initial Magnetic Field Model
Authors: Jiang Yi , Finlay Christopher C. , Olsen Nils , Tøffner‐Clausen Lars , Yan Qing , Zhang Keke 
Published: November 2024

AbstractEight months of vector magnetic field measurements from the Macau Scientific Satellite‐1 (MSS‐1), supplemented by higher latitude field intensity measurements from the Swarm satellites, are used to derive an MSS‐1 Initial Field Model (MIFM). Robust root‐mean‐square misfits between MIFM and the three components of the MSS‐1 vector field data are found to be below 3.3 nT. MIFM agrees well with the CHAOS‐7 field model and we find even better agreement with an identically parameterized model derived only from Swarm data. MSS‐1 and Swarm vector data can moreover be fit simultaneously with only a small increase in misfit (by less than 0.2 nT). We show that both lithospheric anomalies and core surface field changes can be studied using MSS‐1 data. With its fast coverage of local times MSS‐1 is a valuable addition to the global geomagnetic observing system.