bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-resolution imaging of the evolving bipolar outflows in symbiotic novae: The case of the RS Ophiuchi 2021 nova outburst
Authors: Lico R. , Giroletti M. , Munari U. , O’Brien T. J. , Marcote B. , Williams D. R. A. , Yang J. , Veres P. , Woudt P. 
Published: November 2024

Context. The recurrent and symbiotic nova RS Ophiuchi (RS Oph) underwent a new outburst phase during August 2021, about 15 years after the last event that occurred in 2006. This outburst represents the first nova event ever detected at very high energies (VHE, E > 100 GeV), and a whole set of coordinated multiwavelength observations were triggered by this event.
Aims. The main goals of this work are to characterize the evolving morphology of the expanding bipolar ejecta with high accuracy and to determine the physical conditions of the surrounding medium in which they propagate.
Methods. By means of high-resolution very long baseline interferometry (VLBI) radio observations, we monitored RS Oph with the European VLBI Network (EVN) and e-MERLIN at 1.6 and 5 GHz during multiple epochs from 14 to 65 days after the explosion.
Results. We reveal an evolving source structure consisting of a central and compact core and two elongated bipolar outflows expanding on opposite sides of the core in the east-west direction. The ejecta angular separation with time is consistent with a linear expansion with an average projected speed of ∼7000 km s−1. We find clear evidence of a radial dependence of the density along the density enhancement on the orbital plane (DEOP), going from 1 × 107 cm−3 close to the central binary to 9 × 105 cm−3 at ∼400 AU.
Conclusions. Thanks to the accurate source astrometric position provided by Gaia DR3, in this work we draw a detailed scenario of the geometry and physics of the RS Oph evolving source structure after the most recent nova event. We conclude that most of the mass lost by the red giant companion goes into the DEOP, for which we estimate a total mass of 6.4 × 10−6 M⊙, and into the circumstellar region, while only a small fraction (about one-tenth) is accreted by the white dwarf.
The SOFIA Massive (SOMA) Star Formation Q-band follow-up
Authors: Taniguchi Kotomi , Gorai Prasanta , Tan Jonathan C. , Gómez-Garrido Miguel , Fedriani Rubén , Yang Yao-Lun , Tirupati Kumara Sridharan , Tanaka Kei E. I. , Saito Masao , Zhang Yichen , Morgan Lawrence , Cosentino Giuliana , Law Chi-Yan 
Published: November 2024

Context. Evidence that the chemical characteristics around low- and high-mass protostars are similar has been found: notably, a variety of carbon-chain species and complex organic molecules (COMs) form around both types. On the other hand, the chemical compositions around intermediate-mass (IM) protostars (2 M⊙ < m* < 8 M⊙) have not been studied with large samples. In particular, it is unclear the extent to which carbon-chain species form around them.
Aims. We aim to obtain the chemical compositions of a sample of IM protostars, focusing particularly on carbon-chain species. We also aim to derive the rotational temperatures of HC5N to confirm whether carbon-chain species are formed in the warm gas around these stars.
Methods. We conducted Q-band (31.5–50 GHz) line survey observations toward 11 mainly IM protostars with the Yebes 40 m radio telescope. The target protostars were selected from a subsample of the source list of the SOFIA Massive Star Formation project. Assuming local thermodynamic equilibrium, we derived the column densities of the detected molecules and the rotational temperatures of HC5N and CH3 OH.
Results. Nine carbon-chain species (HC3N, HC5N, C3H, C4H linear-H2CCC, cyclic-C3H2, CCS, C3S, and CH3CCH), three COMs (CH3OH, CH3CHO, and CH3CN), H2CCO, HNCO, and four simple sulfur-bearing species (13CS, C34S, HCS+, and H2CS) are detected. The rotational temperatures of HC5N are derived to be ~20–30 K in three IM protostars (Cepheus E, HH288, and IRAS 20293+3952). The rotational temperatures of CH3OH are derived in five IM sources and found to be similar to those of HC5N.
Conclusions. The rotational temperatures of HC5N around the three IM protostars are very similar to those around low- and high-mass protostars. These results indicate that carbon-chain molecules are formed in lukewarm gas (~20–30 K) around IM protostars via the warm carbon-chain chemistry process. Thus, carbon-chain formation occurs ubiquitously in the warm gas around protostars across a wide range of stellar masses. Carbon-chain molecules and COMs coexist around most of the target IM protostars, which is similar to the situation for low- and high-mass protostars. In summary, the chemical characteristics around protostars are the same in the low-, intermediate- and high-mass regimes.
Die Rechtsfrage: – Wie ist die Rechtslage bei der Behandlung von Kindern?
Authors: Schlegel Thomas 
Published: November 2024

Darf ich in der Behandlung von Kindern beiden Erziehungsberechtigten alles über die Therapie erzählen oder gibt es hier Ausnahmen in Bezug auf die Schweigepflicht?
Therapeutin aus Sachsen
Wohnsituation von Menschen mit schweren psychischen
Erkrankungen
Authors: Lamp Natalie , Breilmann Johanna , Becker Thomas , Allgöwer Andreas , Kilian Reinhold , Gühne Uta , Riedel-Heller Steffi G. , Hasan Alkomiet , Falkai Peter , Ajayi Klemens , Brieger Peter , Frasch Karel , Heres Stephan , Jäger Markus , Küthmann Andreas , Putzhammer Albert , Schneeweiß Bertram , Schwarz Michael , Kösters Markus 
Published: November 2024

Zusammenfassung
Ziel der Studie Psychisch erkrankte Menschen sollten selbstbestimmt in der
Gemeinde wohnen, es findet sich starke Evidenz für diese Wohnform. In dieser
Arbeit wurden die Wohnsituation von Menschen mit schweren psychischen
Erkrankungen, die Inanspruchnahme und der Bedarf an Versorgungsangeboten
analysiert.
Methodik Es wurden Daten einer Querschnittsstudie mit 397 Menschen mit
schweren psychischen Erkrankungen aus zwei bayerischen Bezirken verwendet und
deskriptiv ausgewertet.
Ergebnisse 70% der Betroffenen wohnen eigenständig. 6% leben im ambulant
oder stationär betreuten Wohnen. 25% der Betroffenen sind auf Hilfe beim Wohnen
angewiesen, wobei 39% hiervon nicht die nötige Hilfe erhalten. Die betreuenden
Wohnformen sind den meisten Betroffenen bekannt und wurden als hilfreich
empfunden.
Schlussfolgerung Die meisten Betroffenen leben in einer der
gesellschaftlichen Norm entsprechenden Wohnsituation. Dennoch besteht bei einem
Teil der Betroffenen ein ungelöstes Wohnproblem. Die Inanspruchnahme von
ambulant oder stationär betreutem Wohnen ist hilfreich, die Unterstützung wird
aber kaum genutzt.
Epidermoid Cyst with Bilateral Premedullary Involvement Resected from Left Far-Lateral Approach
Authors: Bialek Shannan , Zhao Xiaochun , Stevens Baylee , Bien Alexander , Graffeo Christopher S. 
Published: November 2024

AbstractThe patient is a 51-year-old woman with an epidermoid cyst extending bilaterally along the clivus and cerebellopontine angles from the level of the cisterna magna to the prepeduncular cistern. Her presenting symptoms included hearing loss, tinnitus, and imbalance for 4 months. Near-complete resection of the epidermoid cyst was achieved via a left far-lateral approach. The patient did well after the procedure with no new permanent cranial nerve deficits and unchanged or slightly improved preoperative deficits.
Studiendaten zum NSCLC: spannend, aber nicht praxisverändernd
Authors: Schöllmann Claudia 
Published: November 2024

ZusammenfassungDer ESMO-Jahreskongress 2024 lieferte interessante Studiendaten zum nichtkleinzelligen Lungenkarzinom (NSCLC), die vor allem das Wissen zu vielversprechenden Medikamenten, deren Kombinationen und etablierten zielgerichteten Therapien sowie zu Resistenzmechanismen erweiterten.
Association between colonoscopy and colorectal cancer occurrence and mortality in the older population: a population-based cohort study
Authors: Lee Ji Young , Cha Jae Myung , Yoon Jin Young , Kwak Min Seob , Lee Hun Hee 
Published: November 2024

AbstractWe aimed to evaluate the association between colonoscopy and colorectal cancer (CRC) occurrence and related mortality in an older population.This retrospective, nationwide, population-based cohort study used data of adults aged ≥40 years from the Health Insurance Review and Assessment Service database. After excluding colonoscopy within 6 months of CRC diagnosis during enrollment, CRC occurrence and related mortality were compared between colonoscopy and non-colonoscopy groups using a time-dependent Cox proportional hazard model. Subgroup analysis was conducted among four age groups: young, middle-aged, old, and very old.Among 748986 individuals followed for 9.64 (SD 0.99) years, the colonoscopy group had a
65% lower CRC occurrence (adjusted hazard ratio [HRa] 0.35, 95%CI 0.32–0.38) and 76% lower
CRC-related mortality (HRa 0.24, 95%CI 0.18–0.31) after 5 years compared with the
non-colonoscopy group. Colonoscopy was associated with the most significant reduction in CRC
occurrence in the middle-aged group (HRa 0.32, 95%CI 0.29–0.35) and in CRC-related mortality
in the young group (HRa 0.04, 95%CI 0.01–0.33); the very old group had the least reduction
in both CRC occurrence and CRC-related mortality (HRa 0.44, 95%CI 0.33–0.59 and HRa 0.28,
95%CI 0.15–0.53, respectively).We found a significant association between colonoscopy and reduction in CRC occurrence and CRC-related mortality in adults aged ≥40 years after 5 years of follow-up; however, these associations were weaker in the very old group. More research is needed on the association between colonoscopy and older age.
High-Flow Arteriovenous Malformations: Treatment Using a Venous Approach
Authors: Funaki Brian 
Published: November 2024

AbstractHigh-flow arteriovenous malformations (AVMs) are among the rarest and most recalcitrant lesions in medicine. Patients with these anomalies are best managed longitudinally in tertiary referral centers by dedicated multidisciplinary teams that include surgeons, dermatologists, hematologists, geneticists, and interventional radiologists. A significant percentage of these lesions cannot be cured per se and intervention can worsen symptoms or preclude effective future embolization. Existing classification systems help guide treatment, but in nearly all cases, therapy must be individualized based on patient, symptoms, and lesion angioarchitecture. For various reasons, referral to tertiary centers may be impossible for some patients. The purpose of this article is to provide an approach to the evaluation and treatment of these abnormalities.
What the Interventional Radiologist Needs to Know about the Genetics of Vascular Anomalies
Authors: Josephs Shellie , Martin Lynne , Josephs Travis , Hovsepian David 
Published: November 2024

AbstractThe purpose of this article is to familiarize the reader with the basic genetics and vascular biology behind the array of vascular anomalies they may encounter in their practice. Individuals with vascular malformations are often referred to multidisciplinary clinics composed of diverse specialists all with the same goal: how to provide the best care possible. The team is typically composed of physicians, nurses, social workers, and technical staff from multiple specialties including diagnostic and interventional radiology, dermatology, hematology/oncology, otolaryngology, plastic surgery, and several additional subspecialties. Imaging plays a crucial role in diagnosis and treatment planning, but increasingly biopsies are needed for more accurate histopathological and genetic information to inform the plan of treatment, as well as for counseling patients and their families on the natural history, heritability, and long-term prognosis of the condition. Understanding the molecular mechanism that gives rise to vascular anomalies is crucial for arriving at the proper diagnosis and choosing among treatment options. As oncological medications are being increasingly repurposed to treat vascular malformations, it is vital for those caring for patients with vascular anomalies to understand how these anomalies develop, and which drug may be appropriate to repurpose for this benign disease.
Type-1 spinal muscular atrophy cohort before and after disease-modifying therapies
Authors: Alves Brenda Klemm Arci Mattos de Freitas , Araujo Alexandra Prufer de Queiroz Campos , Santos Flávia Nardes dos , Ribeiro Márcia Gonçalves 
Published: November 2024

Abstract
Background Spinal muscular atrophy (SMA-5q) is a neurodegenerative disease characterized by progressive muscle atrophy, hypotonia, and weakness, with SMA 1 presenting symptoms within the first 6 months of life. Disease-modifying therapies have been approved, with better outcomes with earlier treatment.
Objective To describe the safety and clinical efficacy of disease-modifying therapies based on SMN1 and SMN2 gene strategies concerning motor, respiratory, and bulbar function. Patients with SMA 1 were divided into 2 groups: those exclusively on nusinersen (group 1) and those transitioning to onasemnogene abeparvovec (OA) (group 2).
Methods Over 18 months, patients were assessed using the Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND) scale, developmental milestones, ventilation needs and duration, nutritional support needs, consistency of food, and signs of dysphagia. There were ten patients, divided between the groups; in group 1, the average age for starting nusinersen was 53.6 (12–115) months, and, in group 2, the age was 7 (1–12) months for nusinersen and 15.2 (10–19) months for OA.
Results Our results indicate that 70% of patients reached some motor milestones, with group 1 increasing by 10.2 points on the CHOP-INTEND scale, while group 2 increased by 33 points. Additionally, 90% of the patients experienced no respiratory decline, and 30% maintained oral feeding. No serious adverse effects or deaths were recorded.
Conclusion Both groups showed improvement in motor function and stabilization of respiratory and bulbar function, with the difference between the groups possibly being related to the earlier treatment initiation. Thus, the present study provides valuable insights into the real-world safety and clinical efficacy of disease-modifying therapies for SMA 1 patients.
High-Grade Gastrointestinal Neuroendocrine Carcinomas: Multidisciplinary Approach Can Improve Survival Outcomes
Authors: Syed Noorzia , Ramaswamy Anant , Dhanawat Aditya , Joarder Ritam , Choudhary Jatin , Patel Dhwani , Bhargava Prabhat , Bal Munita , Yadav Subhash , Bhandare Manish , Chaudhari Vikram , Shrikhande Shailesh V. , Goel Mahesh , Patkar Shraddha , deSouza Ashwin , Saklani Avanish , Kazi Mufaddal , Puranik Ameya , Ostwal Vikas 
Published: November 2024

Purpose There is limited evidence for the presentation patterns and outcomes of patients with high-grade gastrointestinal neuroendocrine carcinomas (HG-NEC).
Methods Patients diagnosed with HG-NEC, defined as having a pathological diagnosis of neuroendocrine cancer with an epicenter of cancer in the gastrointestinal tract and Molecular Immunology Borstel-1 index ≥ 20% between May 2014 and May 2022 were retrospectively analyzed for demographic variables, survivals, and prognostic parameters. The primary endpoint of the study was the estimation of median overall survival (OS) by the Kaplan–Meier method.
Results A total of 336 patients were included in the analysis, of whom 283 patients (84%) were started on cancer-directed treatment while 53 patients (16%) were planned for best supportive care. The most common sites of the primary were gallbladder (45%), colorectal (19%), and pancreas (13%), with 253 patients (75%) having metastatic NEC. All treated patients received systemic therapy (commonly platinum and etoposide), while 64 patients (23%) underwent resection of the primary. With a median follow-up of 65.4 (45.6 -85.3) months, the median OS of the entire cohort was 15.8 months. The prospective multidisciplinary tumor (MDT) board decision of classifying patients into resectable, unresectable, and metastatic HG-NEC was prognostic for OS (26.8 vs. 21.1 vs. 13.5 months; p = 0.001). Patients who were able to undergo multimodality therapy (resection and systemic therapy) had improved OS compared with patients on systemic therapy alone (23.1 vs. 14.9 months; p = 0.003).
Conclusion A majority of patients with HG-NEC present with advanced disease. An MDT is essential to deciding initial therapeutic strategies in these patients, with patients undergoing resection and systemic therapy having improved OS.
Reinforcement Learning for Efficient Identification of Soliton System Parameters Across Expansive Domains
Authors: Hu Cheng , Zhang Zhiyang , Liu Muwei , Xiang Liuyu , Wu Huijia , Liu Wenjun , He Zhaofeng 
Published: November 2024

Abstract
Optical solitons in mode-locked fiber lasers and optical communication links have various applications. The study of transmission modes of optical solitons necessitates the investigation of the relationship between the equation parameters and soliton evolution employing deep learning techniques. However, the existing identification models exhibit a limited parameter domain search range and are significantly influenced by initialization. Consequently, they often result in divergence toward incorrect parameter values. This study harnessed reinforcement learning to revamp the iterative process of the parameter identification model. By developing a two-stage optimization strategy, the model could conduct an accurate parameter search across arbitrary domains. The investigation involved several experiments on various standard and higher-order equations, illustrating that the innovative model overcame the impact of initialization on the parameter search, and the identified parameters are guided toward their correct values. The enhanced model markedly improves the experimental efficiency and holds significant promise for advancing the research of soliton propagation dynamics and addressing intricate scenarios.
Exploring fast domain wall motion and DMI realization in compensated ferrimagnetic nanowires
Authors: Mohammadi Mojtaba , Ranjbar Sina , Thach Pham Van , Sumi Satoshi , Tanabe Kenji , Awano Hiroyuki 
Published: November 2024

Abstract
Recent advancements in spintronics have spurred interest in current-induced domain wall motion as a promising avenue for next-generation memory technologies. While previous research has predominantly focused on thin ferromagnetic films, recent attention has shifted towards ferrimagnetic materials due to their potential for magnetization compensation and efficient domain wall (DW) motion. In this study, we investigated the dynamics of DWs in compensated ferrimagnetic Pt/Gd
x
Fe1−x
nanowires through experimental characterization and analysis. Our results reveal fast DW motion around the magnetic compensation point, indicating the influence of spin–orbit torque induced by current flow. We systematically explore the Dzyaloshinskii–Moriya interaction (DMI) field across different compositions of GdFe, observing elevated DMI field values near the compensation compositions. Additionally, we examine the impact of wire width and pulse duration on DW velocity, demonstrating higher velocities in narrower wires and shorter pulse durations. In the 1 μm wire, a DW velocity of around 3200 m s−1 was achieved by applying a 3 ns short pulse current. Our findings elucidate the intricate interplay between film composition, magnetic properties, wire width, pulse duration, and DW dynamics, providing valuable insights for the design and optimization of ferrimagnetic materials for future magnetic memory technologies.
Review of nonflow estimation methods and uncertainties in relativistic heavy-ion collisions
Authors: Feng Yicheng , Wang Fuqiang 
Published: November 2024

Abstract
Collective anisotropic flow, where particles are correlated over the entire event, is a prominent phenomenon in relativistic heavy-ion collisions and is sensitive to the properties of the matter created in those collisions. It is often measured by two- and multi-particle correlations and is therefore contaminated by nonflow, those genuine few-body correlations unrelated to the global event-wise correlations. Many methods have been devised to estimate nonflow contamination with various degrees of successes and difficulties. Here, we review those methods pedagogically, discussing the pros and cons of each method, and give examples of ballpark estimate of nonflow contamination and associated uncertainties in relativistic heavy-ion collisions. We hope such a review of the various nonflow estimation methods in a single place would prove helpful to future researches.
Investigating the impact of ITO substrates on the optical and electronic properties of WSe2 monolayers
Authors: Brito Thiago G L , Costa Fábio J R , Ceccatto Alisson , de Almeida Charles A N , de Siervo Abner , Couto Odilon D D , Barcelos Ingrid David , Zagonel Luiz Fernando 
Published: November 2024

Abstract
Two-dimensional (2D) materials, particularly transition metal dichalcogenides (TMDs), have gathered significant attention due to their interesting electrical and optical properties. Among TMDs, monolayers of WSe2 exhibit a direct band gap and high exciton binding energy, which enhances photon emission and absorption even at room temperature. This study investigates the electronic and optical properties of WSe2 monolayers when they are mechanically transferred to indium tin oxide (ITO) substrates. ITO is a transparent conducting electrode (TCE) used in many industrial optoelectronic applications. Samples were mechanically transferred under ambient conditions, consequently trapping an adsorbate layer of atmospheric molecules unintentionally between the monolayer and the substrate. To reduce the amount of adsorbates, some samples were thermally annealed. Atomic force microscopy confirmed the presence of the adsorbate layer under the TMD and its partial removal after annealing. X-ray photoelectron spectroscopy confirmed the presence of carbon species among the adsorbates even after annealing. Photoluminescence measurements show that WSe2 remains optically active on ITO even after annealing. Moreover, the luminescence intensity and energy are affected by the amount of adsorbates under the WSe2 monolayer. Scanning tunnelling spectroscopy reveals that the TMD monolayer is n-doped, and that its band edges form a type I band alignment with ITO. Surface potential measurements show a polarity change after annealing, indicating that polar molecules, most likely water, are being removed. This comprehensive study shows that a TCE does not quench WSe2 luminescence even after a prolonged thermal annealing, although its optical and electronic properties are affected by unintentional adsorbates. These findings provide insights for better understanding, controlling, and design of 2D material heterostructures on TCEs.