bluuebunny/crossref_metadata_2025_split huggingface dataset:
El discurso anti-islámico castellano: de disputa teológica a cimiento del proyecto universalista carolino (1460–1530)
Authors: Cavallero Constanza 
Published: September 2019

Abstract
From a comparative perspective, I will study two anti-Islamic Castilian writings produced during the period of the transition between the Middle Ages and the Early Modern Era: Alonso de Espina’s Fortalitium fidei (1460) and Gonzalo de Arredondo’s Castillo inexpugnable defensorio de la fe (1528). This study compares the terms in which each of these works addresses (a) the confrontation with Islam, (b) dissensions within Christianity, and (c) the king’s role in the midst of those conflicts. The contrastive approach to these analogous works, which were written almost seven decades apart, will allow an analysis of two different articulations of anti-Saracen Christian discourse in Spain, both before and after some key milestones in European history. These different perceptions of Islam had an impact on the conception of Christianity and Europe itself at the very beginning of the early modern period.
EU Citizens, Residence Rights and Solidarity in the Post-Dano/Alimanovic Era in Germany
Authors: Devetzi Stamatia 
Published: September 2019

Abstract
The Dano and Alimanovic decisions of the ECJ have triggered various developments in German social security law and (social) court jurisprudence. While the German courts’ rulings regarding the rights of non-active EU migrants still vary, the legislator has moved towards excluding more EU citizens from receiving non-contributory benefits. In the aftermath of Dano and, more specifically, Alimanovic, the provisions of Book II of the German Social Code were revised at the end of 2016. The new rules not only ‘confirm’ the ECJ-decisions, but also go beyond, as far as to exclude EU migrants who have residence rights according to Reg. (EU) No. 492/2011.
This article discusses these recent developments. It focuses on the ECJ-case law regarding Art. 10 of Reg. (EU) No. 492/2011 (former Art. 12 of Reg. 1612/68), in particular the Ibrahim and Teixeira rulings. Which residence rights do prevail—those according to Dir. 2004/38/EC or those based on Reg. (EU) No. 492/2011? It is argued that a new discussion on the interrelation between Dir. 2004/38/EC and Reg. (EU) No. 492/2011—an aspect ignored by the German legislator—is emerging: What started as a restriction of access to national welfare for economically non-active persons has obviously reached the ‘economically active’ (= workers) as well. The German example shows that Member States may be testing which other residence rights—in addition to those for short stays and job searches—might be valid before the ECJ ‘as residence rights without social rights’.
EU Citizens, Foreign Family Members and European Union Law
Authors: Guild Elspeth 
Published: September 2019

Abstract
While international human rights law enshrines family life as a cornerstone of society, when it intersects with migration, issues and problems arise in countries where migration is high on the political agenda. This is true in a number of EU states. Both EU law and European human rights commitments, however, require states to provide for family reunification subject to a margin of discretion to the state. While family reunification for refugees and beneficiaries of international protection has been at the top of some political agendas in Europe, this article looks at family reunification (generally known as family reunion) for another group—nationals of the Member States. In particular it poses two questions: do EU Member States accept their own nationals to come back to their home state with third country national family members they have acquired while abroad? Secondly, to what extent do EU Member States discriminate against their own nationals in comparison with the generous EU rules of family reunion for nationals of other Member States who have exercised a free movement right in their country. This article is based on reports by experts from all EU Member States in light of the 2014 judgment in O & B (C-456/12) by the Court of Justice of the European Union.
The Role of Travaux in Interpreting BIT Provisions: Are Tribunals Over-Prepared to Resort to Preparatory Works?
Authors: Panjwani Pratyush 
Published: September 2019

Abstract
While multilateral investment treaties have formed the centrepiece of much academic discourse, an uncharacteristic literary silence has eclipsed the issue of interpretation of bilateral investment treaties under the scheme of the Vienna Convention on the Law of Treaties (VCLT). This article travels this untraversed territory by revisiting the basics of the principles encapsulated in the hierarchical set-up of Articles 31 and 32 VCLT, and juxtaposing this foundational set-up against its frequent oversights by investment tribunals. These oversights are exemplified by the divergent interpretative analyses afforded to umbrella and most-favoured-nation clauses, and emanate from a premature resort to the travaux préparatoires of investment treaties under Article 32 VCLT. Ultimately, the article argues that a proper application of the VCLT would go a long way in eliminating the contradictions tainting the understanding of the aforesaid clauses.
Intraseasonal Variability of the Diurnal Cycle of Precipitation in the Philippines
Authors: Natoli Michael B. , Maloney Eric D. 
Published: September 2019

AbstractPrecipitation in the region surrounding the South China Sea over land and coastal waters exhibits a strong diurnal cycle associated with a land–sea temperature contrast that drives a sea-breeze circulation. The boreal summer intraseasonal oscillation (BSISO) is an important modulator of diurnal precipitation patterns, an understanding of which is a primary goal of the field campaign Propagation of Intraseasonal Tropical Oscillations (PISTON). Using 21 years of CMORPH precipitation for Luzon Island in the northern Philippines, it is shown that the diurnal cycle amplitude is generally maximized over land roughly 1 week before the arrival of the broader oceanic convective envelope associated with the BSISO. A strong diurnal cycle in coastal waters is observed in the transition from the inactive to active phase, associated with offshore propagation of the diurnal cycle. The diurnal cycle amplitude is in phase with daily mean precipitation over Mindanao but is nearly out of phase over Luzon. The BSISO influence on the diurnal cycle on the eastern side of topography is nearly opposite to that on the western side. Using wind, moisture, and radiation products from the ERA5 reanalysis, it is proposed that the enhanced diurnal cycle west of the mountains during BSISO suppressed phases is related to increased insolation and weaker prevailing onshore winds that promote a stronger sea-breeze circulation when compared with the May–October mean state. Offshore propagation is suppressed until ambient midlevel moisture increases over the surrounding oceans during the transition to the active BSISO phase. In BSISO enhanced phases, strong low-level winds and increased cloudiness suppress the sea-breeze circulation.
Evapotranspiration Reconstruction Based on Land Surface Models and Observed Water Budget Components While Considering Irrigation
Authors: Lv Meixia , Ma Zhuguo , Chen Liang , Peng Shaoming 
Published: September 2019

AbstractThe accurate estimation of evapotranspiration (ET) is essential for understanding the land surface–atmosphere interaction; however, current ET products have large uncertainties, and irrigation effects on ET are not well represented. In this study, the monthly ET was reconstructed (ETrecon) from GLDAS land surface models (LSMs) over the Yellow River basin of China, which was achieved by using observation-based precipitation, naturalized streamflow, and downscaled consumed irrigation water from the census annual data via an irrigation scheme. The results showed that the monthly ETrecon series were generally improved relative to the original LSM-based ET, with improvements in the correlation coefficient, Nash–Sutcliffe efficiency, mean absolute error, and root-mean-square error by 0.6%–1.8%, 1.2%–14.6%, 1.3%–21.0%, and 2.1%–20.4%, respectively. The ETrecon results were also superior to the collected ET synthesis products in terms of statistics, with generally higher peak values occurring in ETrecon. Regarding the annual time scale, the ETrecon values were close to the water balance ET values, which have been widely used as benchmark data. The interannual variability in ETrecon was good overall and was associated with the LSM precipitation variability and partitioning of precipitation into ET and runoff. The reconstruction method can provide an alternative ET estimate for other river basins. This study will also be valuable for studies and applications in climate change evaluation, drought assessment, and water resources management.
A Sea Trial of Air-Lift Concept Artificial Upwelling in the East China Sea
Authors: Pan Yiwen , Li Yifan , Fan Wei , Zhang Dahai , Qiang Yongfa , Jiang Zong-Pei , Chen Ying 
Published: September 2019

AbstractArtificial upwelling (AU), as one of the geoengineering tools, has received worldwide attention because of its potential ability to actualize ocean fertilization in a sustainable way. The severe challenges of AU are the design and fabrication of a technologically robust device with structural longevity that can maintain the function in the variable and complex hydrodynamics of the upper ocean. In this work, a sea trial of an air-lift concept AU system driven by self-powered energy was carried out in the East China Sea (ECS; 30°8′14″N, 122°44′59″E) to assess the logistics of at-sea deployment and the durability of the equipment under extremely complex hydrodynamic conditions from 3 to 7 September 2014. Seawater below the thermocline layer was measured to be uplifted from approximately 30 m to the euphotic layer with a volumetric upwelling rate of 155.43 m3 h−1 and total inputs of 2.8 mol h−1 NO3−, 0.15 mol h−1 PO43−, and 4.41 mol h−1 SiO43−. A plume formed by cold, saline deep ocean water (DOW) was tracked by a drifting buoy system with a mixing ratio of 37%–51% DOW at the depth of 18–22 m, which conforms to the simulation results. During the AU’s application, disturbance in the vertical hydrological structure could be observed. However, diatom (Skeletonema costatum) blooming from somewhere in the outer ECS floated to the sea trial region on the second day after the AU’s application, which makes it hard to strip off the biochemical effects of AU from the effects of S. costatum bloom.
Rhinosinusitis in Pediatric Primary Ciliary Dyskinesia: Impact of Disease
Authors: Bhatt Jay M. , Muhonen Ethan G. , Meier Maxene , Sagel Scott D. , Chan Kenny H. 
Published: September 2019

ObjectivesPrimary ciliary dyskinesia (PCD) is a genetic disorder characterized by abnormal respiratory cilia ultrastructure and/or function causing defective mucociliary clearance. We investigated the extent and severity of rhinosinusitis in a large cohort of children with PCD and explored associations among risk factors, including genotype and sinus disease.Study DesignRetrospective chart review.SettingTertiary academic children’s hospital.Subjects and MethodsA review was conducted with a patient registry at the PCD Foundation Center at our institution. Demographic, imaging, clinical, and operative data were reviewed through the institutional electronic health record system.ResultsFifty‐four subjects were identified with mean and median age at diagnosis of 5.2 and 4.0 years. The male:female ratio was 35%:65%. Sinus symptoms were present in 46 (85%) subjects, 22 of whom had chronic rhinosinusitis. Nineteen (35%) subjects underwent operative intervention, consisting of endoscopic sinus surgery (ESS; 16 patients) and maxillary lavage (3 patients). Nineteen subjects underwent adenoidectomy for PCD‐related indications. Five sinus‐related admissions in 3 subjects were noted during the study period, and no complication of rhinosinusitis occurred in the cohort. Genetic test results were available in 27 subjects, in whom 23 (85%) had biallelic mutations in a PCD gene. Demographic factors, Lund‐Mackay score, and PCD genotype were not found to be predictors for ESS or hospitalization in our cohort.ConclusionWhile rhinosinusitis was common in our PCD cohort, most patients did not require ESS. Since complications of rhinosinusitis were uncommon, we recommend judicious surgical management tailored to the patient’s symptoms.
Hypocaloric, plant-based oatmeal interventions in the treatment of poorly-controlled type 2 diabetes: A review
Authors: Storz Maximilian Andreas , Küster Onno 
Published: September 2019

Background: Lifestyle interventions, including dietary modifications, play a key role in the treatment of type 2 diabetes. By the second half of the last century, dietary oatmeal interventions had frequently been used in patients with diabetes; however, with the widespread introduction of insulin, this practice gradually fell into disuse. Within the last decades, the original oatmeal intervention, first described in 1903, has been modified towards a hypocaloric, low-fat, and plant-based intervention. Aim: The aim of this review was to investigate the current role of these adapted short-term dietary oatmeal interventions in the treatment of patients suffering from poorly-controlled type 2 diabetes. A special focus was put on opportunities for and barriers to its clinical implementation and its potential mechanisms of action. Methods: The electronic databases of PubMed and Google Scholar were searched using the keywords “oat,” “oats,” “oatmeal,” and “diabetes.” Results: While there are a limited number of clinical studies including hypocaloric short-term dietary oatmeal interventions, there is evidence that these interventions may lead to a significant decrease in mean blood glucose levels and a significant reduction of insulin dosage in patients suffering from poorly-controlled type 2 diabetes. Conclusion: Modified short-term dietary oatmeal interventions are an effective and economical tool in the treatment of patients suffering from poorly-controlled type 2 diabetes.
Disparities in Pediatric Epilepsy Remission Are Associated With Race and Ethnicity
Authors: Gregerson Celestine H. Yeung , Bakian Amanda V. , Wilkes Jacob , Knighton Andrew J. , Nkoy Flory , Sweney Matthew , Filloux Francis M. , Bonkowsky Joshua L. 
Published: September 2019

Objective: The purpose of our study was to assess whether race/ethnicity was associated with seizure remission in pediatric epilepsy. Methods: This was a retrospective population-based cohort study of children who were evaluated for new-onset epilepsy in the clinic, emergency department, and/or hospital by a pediatric neurologist in an integrated health care delivery system. Children were between ages 6 months and 15 years at their initial presentation of epilepsy. The cohort, identified through an electronic database, was assembled over 6 years, with no less than 5 years of follow-up. All children were evaluated for race, ethnicity, insurance type, and socioeconomic background. Patient outcome was determined at the conclusion of the study period and categorized according to their epilepsy control as either drug resistant (pharmacoresistant and intractable) or drug responsive (controlled, probable remission, and terminal remission). Results: In the final cohort of 776 patients, 63% were drug responsive (control or seizure remission). After controlling for confounding socioeconomic and demographic factors, children of Hispanic ethnicity experienced reduced likelihood (hazard) of drug-responsive epilepsy (hazard ratio 0.6, P < .001), and had longer median time to remission (8 years; 95% CI 5.9-9.6 years) compared to white non-Hispanic patients (5.6 years; 95% CI 4.9-6.1 years). Among Hispanic patients, higher health care costs were associated with reduced likelihood of drug responsiveness. Significance: We found that Hispanic ethnicity is associated with a reduced likelihood of achieving seizure control and remission. This study suggests that factors associated with the race/ethnicity of patients contributes to their likelihood of achieving seizure freedom.
Acute Neuromuscular Disorders in the Pediatric Intensive Care Unit
Authors: Harrar Dana B. , Darras Basil T. , Ghosh Partha S. 
Published: September 2019

Background: The neuromuscular disorders encountered in the pediatric intensive care unit (PICU) encompass a broad spectrum of pathologies. These include acute disorders (eg, Guillain-Barre syndrome), acute-on-chronic disorders (eg, myasthenia gravis), progressive disorders (eg, muscular dystrophy), and disorders that develop in the PICU (eg, critical illness myopathy/polyneuropathy). Familiarity with the presenting features of these disorders is of paramount importance in facilitating timely diagnosis. Methods: We conducted a retrospective review of the medical records of patients admitted to the PICU or Intermediate Care Program (ICP) at a single tertiary children’s hospital from 2006 to 2017 with an acute or acute-on-chronic neuromuscular disorder. We did not include patients with a known progressive neuromuscular disorder or critical illness myopathy/polyneuropathy. Results: Twenty-four patients were admitted to the PICU/ICP with acute or acute-on-chronic neuromuscular disorders. Diagnosis and indication for ICU/ICP admission were Guillain-Barre syndrome (n = 6; respiratory failure: 3, respiratory monitoring: 2, autonomic instability: 1), myasthenia gravis (n = 5; airway clearance: 3, respiratory failure: 2), acute flaccid myelitis (n = 3; respiratory failure: 2, respiratory monitoring: 1), periodic paralysis (n = 3; intravenous potassium replacement), rhabdomyolysis (n = 3; monitoring for electrolyte derangements), infant botulism (n = 2; respiratory failure), chronic demyelinating polyneuropathy (n = 1; respiratory failure), and congenital myasthenic syndrome (n = 1; apnea). No patients were admitted to the PICU/ICP with a diagnosis of tick paralysis, acute intermittent porphyria, or inflammatory myopathy. Conclusions: Although acute and acute-on-chronic neuromuscular disorders are encountered relatively rarely in the PICU, familiarity with the presenting features of these disorders is important in facilitating timely diagnosis. This, in turn, enables the institution of effective management strategies, thereby avoiding complications associated with diagnostic delays.
Evaluation of cardiomyopathy in acute myeloid leukemia patients treated with anthracyclines
Authors: Mort Meredith K , Sen Jeremy M , Morris Amy L , DeGregory Kathlene A , McLoughlin Erin M , Mort Joseph F , Dunn Steven P , Abuannadi Mohammad , Keng Michael K 
Published: September 2019

Background Acute myeloid leukemia patients receive anthracycline-containing induction chemotherapy. Anthracyclines cause cardiotoxicity; however, there is a paucity of data reflecting the risk of cardiotoxicity in the acute myeloid leukemia population, and risk factors for development of reduced left ventricular ejection fraction are not well established in this population. Methods A retrospective cohort study of adult acute myeloid leukemia patients receiving anthracycline-containing induction chemotherapy between March 2011 and August 2017 was performed. Baseline and all additional cardiac monitoring within one year of induction were collected. Home medications and new medication initiation were determined via the electronic health record and new outpatient prescriptions. Results Of 97 evaluable patients, 25 (25.8%) developed reduced left ventricular ejection fraction and 18 (18.6%) experienced clinical heart failure within one year of induction. The median difference from baseline to lowest left ventricular ejection fraction was −5.0 percentage points, with a range of +10.0 to −52.5. The median time to onset of reduced left ventricular ejection fraction was 27 days, at a median cumulative anthracycline dose of 270 mg/m2. No patient-specific or medication-specific factors were significantly associated with the risk of developing reduced left ventricular ejection fraction. Of 14 patients started on medical management for reduced left ventricular ejection fraction, 10 (71%) responded to therapy. Conclusions In this retrospective analysis, we observed that acute myeloid leukemia patients experienced reduced left ventricular ejection fraction more quickly and at lower doses than previously reported in the solid tumor population. Reduced left ventricular ejection fraction was at least partially reversible in most patients started on medical management. Although no factors were significantly associated with decreased cardiomyopathy risk, future assessment of cardioprotective medications may be warranted.
Treatment of Mycoplasma pneumoniae-Induced Rash and Mucositis With Cyclosporine
Authors: Li Heidi Oi-Yee , Colantonio Sophia , Ramien Michele L. 
Published: September 2019

Background Mycoplasma pneumoniae-induced rash and mucositis (MIRM) is a relatively newly recognized clinical entity that typically presents with predominant mucositis accompanied by variable cutaneous involvement 7-9 days after the onset of prodromal symptoms. There are no evidence-based guidelines for treatment, and current standards of care may include supportive therapy, antibiotics, corticosteroids, and intravenous immunoglobulin . Objective This case series aims to describe the potential efficacy of cyclosporine A (CsA) in the treatment of MIRM. Methods The present case series details our use of CsA early in the course of MIRM in 3 pediatric patients. Results Rapid clinical resolution was observed following CsA therapy. Conclusions We suggest that early initiation of CsA may be an effective therapeutic option for MIRM.