bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALYSIS OF THE OPERATING LOAD OF THE TURBINE ENGINE DURING DECELERATION TO DASH MANEUVER
Authors: Czyż Zbigniew 
Published: October 2019

The article presents the analysis of the loads on the gas generator of turbine engine power of unmanned helicopter. The analysis was performed for deceleration to dash maneuver. Particular attention was paid to loads of bearing assembly in gas generator of turbine engine. The analysis was based on the timelines of changes in velocity of manned helicopter PZL W3-Falcon. The dependence of velocity changes during the flight was made as approximation by the least squares method and then determined for its change in acceleration. On this basis, the forces acting on the bearing gas generator assembly in static and dynamic conditions were determined. These values were compared with values obtained during maneuvers such as "jump up and jump down" and "acceleration and deceleration maneuver".
SISTEM PENCATATAN DAN PENDATAAN MANAJEMEN SUMBER DAYA MANUSIA DENGAN MODEL SCRUM (STUDI KASUS: PT BINTANG TRANS KHATULISTIWA)
Authors: RAHMAN SAEPUR , SETIAWAN ARIS , HANDRIANI INGE 
Published: October 2019

Manajemen sumber daya manusia atau biasa disebut Human Resource Development (HRD) merupakan salah satu bagian terpenting dalam suatu perusahan atau organisasi. Karena, fokus utama manajemen sumber daya manusia adalah memberikan kontribusi bagi sukses atau tidaknya suatu organisai atau perusahaan. Tugas dan kegiatan HRD dalam suatu perusahaan adalah menangani permasalahan-permasalahan yang berkenaan dengan pengelolaan sumber daya manusia pada sebuah organisasi (perusahaan). Pengelolaan data sumber daya manusia pada PT. Bintang Trans Khatulistiwa (BTK) masih bersifat manual, sehingga perusahaan kesulitan dalam memperoleh informasi yang berhubungan dengan sumber daya manusia secara cepat dan akurat. Untuk menangani permasalahan tersebut, maka kami mengusulkan pembuatan suatu sistem informasi manajemen Sumber Daya Manusia yaitu Aplikasi Sistem Pencatatan dan Pendataan Manajemen Sumber daya Manusia yang nantinya dapat membantu bagian HRD untuk menjalankan tugasnya, mulai dari proses pendataan karyawan, pendataan absensi, pengajuan cuti, proses payroll atau penggajian dan penilaian karyawan hingga pembuatan laporan, serta dapat menghasilkan informasi yang dapat digunakan untuk pengambilan keputusan bagi seorang manajer. Dalam pengembangan sistem ini menggunakan pendekatan metode Scrum dan menggunakan metode cause effect diagram (fishbone) sebagai dasar untuk melakukan analisa permasalahan, sehingga nantinya akan didapatkan solusi-solusi untuk pembuatan sistem pada penelitian ini.Keywords— Sistem informasi, sumber daya manusia, Scrum, Fishbone
Analisa Dan Perancangan Aplikasi Sistem Pelayanan Klinik Gigi (Studi Kasus: Dental Echo Clinic)
Authors: Lestari Dewi 
Published: October 2019

Dental Echo Clinic merupakan Klinik gigi yang berada di Tangerang yang dibangun untuk menunjang aspek kesehatan dan pelayanan kesehatan gigi, Echo Dental Clinic memiliki sistem informasi yang berjalan secara konvensional dimana administrasi pasien masih menggunakan formulir. Untuk meningkatkan kinerja Dental Echo Clinic sebagai salah satu pelayanan kesehatan gigi di Tangerang, maka diusulkan sebuah Perancangan sistem informasi pelayanan klinik gigi yang selanjutnya disebut Analisa Dan Perancangan Aplikasi Sistem Pelayanan Klinik Gigi. tujuan penelitian ini untuk Meningkatkan efektivitas waktu dalam pelayanan klinik gigi, Meningkatkan efisiensi sistem pencatatan dalam pelayanan klinik gigi serta untuk Meminimalisir kerugian atas terjadinya kesalahaan pencatatan data pasien. Metode pengembangan untuk Perancangan sistem pelayanan klinik gigi ini menggunakan metode Waterfall. Hasil dalam penelitian ini diharapkan Perancangan sistem ini dapat membantu meningkatkan efektivitas waktu dalam proses pelayanan klinik gigi, membantu meningkatkan efisiensi sistem pencatatan dalam klinik gigi secara cepat dan akuat, serta dapat membantu meminimalisir kerugian atas terjadian kesalahan pencatatan data pasien. memberikan solusi dari permasalahan yang timbul ketika sistem yang ada masih menggunakan cara konvensional, perancangan sistem ini mempermudah proses pencarian data pasien, rekam medis, proses pengolahan data administrasi pasien, membuat laporan dan dapat memudahkan petugas dalam melakukan pekerjaannya. Keywords— klinik, system informasi, waterfall, rekamedis.
Faktor-Faktor yang Berhubungan dengan Kejadian Abortus di RSUD Raden Mattaher Provinsi Jambi
Authors: Rosadi Erik , Fithiyani Fithiyani , Hidayat Muhammad 
Published: October 2019

Abortus adalah terhentinya kehamilan sebelum janin mampu hidup di luar kandungan pada usia kurang dari 28 minggu, karena sebagian besar keguguran tidak diketahui dan terjadi secara spontan. Faktor-faktor yang dapat menyebabkan kejadian abortus yaitu hipertensi dalam kehamilan, anemia dalam kehamilan dan usia ibu hamil. Tujuan penelitian untuk melihat fakor-faktor yang berhubungan dengan kejadian abortus di RSUD Raden Mattaher Provinsi Jambi. Penelitian dilaksanakan tanggal 10-24 Juli 2019 dengan jumlah sampel 87 orang. Teknik pengambilan sampel menggunakan simple random sampling. Instrumen penelitian menggunakan lembar observasi. Analisis data menggunakan uji chi square dengan derajat kemaknaan (α) = 0,1. Hasil penelitian tentang hubungan riwayat hipertensi dalam kehamilan dengan kejadian abortus menunujukan bahwa (p value = 0,209) yang berarti tidak ada hubungan riwayat hipertensi dalam kehamilan dengan kejadian abortus dan hubungan anemia dalam kehamilan dengan kejadian abortus (p value = 0,000), dan usia ibu hamil dengan kejadian abortus (p value = 0,005) yang berarti ada hubungan anemia dalam kehamilan dan usia ibu hamil dengan kejadian abortus di RSUD Raden Mattaher Provinsi Jambi. Kesimpulan penelitian ini adalah tidak terdapat hubungan antara riwayat hipertensi dalam kehamilan dengan kejadian abortus dan terdapat hubungan antara anemia dalam kehamilan dan usia ibu hamil dengan kejadian abortus.
The Antiangiogenic Effects of Tamoxifen might be Attributed to Receptor Binding Capacity of its Solvent Dimethylsulfoxide in Breast Cancer: A Molecular Docking Study
Authors: Koçak Orhan , Taşkın Nazlı Deniz , Şimşek Ece 
Published: October 2019

Aim: Tamoxifen, a Dimethyl sulfoxide (DMSO)-soluble chemotherapeutic, is widely used in the treatment of breast cancer. Tamoxifen has an anti-angiogenic effect especially on breast tumor cells by blocking VEGF(Vascular Endothelial Growth Factor) production. On the other hand, according to our previously studies, we demonstrated that DMSO could mimics the cytotoxic effects of Thalidomide in 4T1 mouse breast cancer cells and is related with the anti-angiogenic response of HeLa cells. At this point of view, the aim of this study was to determine the possible binding effects of DMSO on certain cell surface receptors.
Methods: The in silico studies were implemented using the Docking Server. X-ray structures of receptor proteins’ PDB files were obtained from Protein Data Bank [Human Progesteron Receptor (PDB ID: 1A28, Human Tumor Necrosis Factor Receptor-1 (PDB ID: 1EXT), Human Interferon Gamma Receptor-1 (PDB ID: 1FG9), Human Epidermal Growth Factor Receptor (PDB ID: 1IVO)]. Docking simulations were performed using the Lamarckian genetic algorithm (LGA) and the Solis & Wets local search method.
Results: According to the molecular docking results of this study, DMSO, the general solvent of Tamoxifen, has a 90% binding capacity to the Interferon Gamma (IFNɣ) receptor and 100% to Tumor Necrosis Factor alfa (TNFα) receptor, respectively.
Conclusion: These receptors have significant effects on the proliferation and angiogenesis of cancer cells which leads to the metastasis of breast cancer. In conclusion, the antiangiogenic effects of Tamoxifen might be reduced due to its solvent DMSO's angiogenic effects.
Atomic Fluorescence in Environmental Analysis
Authors: Cai Yong , Liu Guangliang 
Published: October 2019

Abstract
Atomic fluorescence spectrometry (AFS) is a highly sensitive, highly selective technique for analysis of some elements, and it has found extensive applications in environmental analysis. This article presents an overview of the theoretical principles and instrumentation design of atomic fluorescence, followed by demonstrations of AFS, stand alone or coupled with other instruments, application in environmental analysis. For analysis of mercury, for which cold vapor generation can be simply and efficiently used as atomization method, and hydride‐forming elements (e.g. arsenic and selenium), for which gaseous hydrides can be easily produced and volatilized, facilitating the separation and enrichment of the analytes, AFS is a particularly useful technique, including speciation analysis of these elements by coupling AFS detection to chromatography separation.
Validating Fitbit for Evaluation of Physical Activity in Patients with Knee Osteoarthritis: Do Thresholds Matter?
Authors: Silva Genevieve S. , Yang Heidi , Collins Jamie E. , Losina Elena 
Published: October 2019

ObjectiveWe sought to evaluate the performance of Fitbit in estimating ActiGraph‐derived moderate‐to‐vigorous physical activity (MVPA) and sedentary time in the knee osteoarthritis (OA) population.MethodsWe used data from two weeks of Fitbit and ActiGraph wear among knee OA subjects. In primary analyses, we used literature‐based ActiGraph thresholds of 200 and 1924 counts/min (triaxial vector magnitude) for sedentary and MVPA time as the gold standard to which we compared three sets of Fitbit thresholds informed by literature and data (Youden index). We also considered personalized, stride length–based Fitbit thresholds. In sensitivity analyses, we used uniaxial, vertical axis–based as well as personalized, BMI‐based ActiGraph thresholds. We calculated agreement, sensitivity, and specificity of Fitbit in classifying sedentary and MVPA time.ResultsIn the primary analysis (vector magnitude thresholds), maximum agreement for sedentary and MVPA time was 67.0% from the Youden index–based and 91.1% from the stride length–based Fitbit thresholds. For sedentary time, the 20 strides/min threshold had the highest sensitivity (97.6%), and Youden‐derived 1 stride/min had the highest specificity (51.6%). For MVPA, Youden‐derived 14 strides/min yielded 72.8% sensitivity, and using stride length yielded 98.6% specificity. MVPA time ranged from 49‐323 min/d, depending on threshold used, with literature‐based and personalized thresholds leading to more conservative estimates of MVPA than Youden‐derived thresholds.ConclusionUsing Fitbit for MVPA and sedentary time assessment may lead to inaccurate estimates of both. Fitbit MVPA estimates were generally more conservative than ActiGraph estimates. Incorporating individuals’ characteristics did not meaningfully improve Fitbit performance. Caution should be exercised when measuring activity using Fitbit.
Rate of CO2 absorption of a phase‐separation absorbent
Authors: Esaki Takehiro , Machida Hiroshi , Norinaga Koyo 
Published: October 2019

AbstractIn this study, we evaluated the CO2 absorption characteristics of a phase‐separation amine absorbent. The phase‐separation absorbent consists of a 30:60:10 (by weight percent) mixture of 2‐(ethylamino)ethanol, diethylene glycol diethyl ether, and water. The CO2 absorption rate of the phase‐separation absorbent was measured in a lab‐scale counter flow absorber. In addition, the CO2 transport phenomena in the absorber were analyzed by performing model fitting. The experimental results revealed that the CO2 absorption rates are different before and after phase separation. In fact, the overall CO2 absorption capacity coefficient after phase separation is 4.5 times higher than that obtained before phase separation. By changing the gas‐liquid ratio, we obtained a CO2 recovery ratio of over 80% using the model. Thus, the absorption temperature, CO2 loading, and gas‐liquid ratio can be tuned to obtain the desired CO2 recovery ratio.
Selenium‐Substituted Diketopyrrolopyrrole Polymer for High‐Performance p‐Type Organic Thermoelectric Materials
Authors: Ding Jiamin , Liu Zitong , Zhao Wenrui , Jin Wenlong , Xiang Lanyi , Wang Zhijie , Zeng Yan , Zou Ye , Zhang Fengjiao , Yi Yuanping , Diao Ying , McNeill Christopher R. , Di Chong‐an , Zhang Deqing , Zhu Daoben 
Published: October 2019

AbstractDevelopment of high‐performance organic thermoelectric (TE) materials is of vital importance for flexible power generation and solid‐cooling applications. Demonstrated here is the significant enhancement in TE performance of selenium‐substituted diketopyrrolopyrrole (DPP) derivatives. Along with strong intermolecular interactions and high Hall mobilities of 1.0–2.3 cm2 V−1 s−1 in doping‐states for polymers, PDPPSe‐12 exhibits a maximum power factor and ZT of up to 364 μW m−1 K−2 and 0.25, respectively. The performance is more than twice that of the sulfur‐based DPP derivative and represents the highest value for p‐type organic thermoelectric materials based on high‐mobility polymers. These results reveal that selenium substitution can serve as a powerful strategy towards rationally designed thermoelectric polymers with state‐of‐the‐art performances.
Novel approach of making porous polyurethane membrane and its properties for apparel application
Authors: Jahid Md Anwar , Hu Jinlian , Thakur Suman 
Published: October 2019

ABSTRACTPorous polyurethane (PPU) membranes have particular significance for various uses, for example, laminated textiles, cell seeding, biomaterials, tissue engineering, and so forth. In this research, the synthesis of segmented PUs was conducted using a two‐step polymerization method and additional highly PPU membranes were produced by the leaching technique, using highly water‐soluble silica particles. A crucial discovery during this work was reducing the particle leaching time. To make a porous structure, the particles were leached out from the PU matrix over 5 min through sonication. An investigation was conducted into the surface morphology of the PPU membrane using a scanning electron microscopy. The microporous average diameter was approximately 2 μm. Thermogravimetric analysis, differential scanning calorimetry, water vapor transmitting, and water droplet resisting ability were the tests conducted to explore the properties of the porous membrane. The effects of different silica particle percentage ratios were investigated. Additionally, a highly porous membrane was laminated with fabric to obtain a water drop resistant, water vapor transmittable, and mechanically strong textile. Such a highly porous promising PU membrane may have a use in tissue engineering and laminated textiles. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48566.
Mendelian randomization study of telomere length and lung cancer risk in East Asian population
Authors: Cao Xuguang , Huang Mingtao , Zhu Meng , Fang Rui , Ma Zijian , Jiang Tao , Dai Juncheng , Ma Hongxia , Jin Guangfu , Shen Hongbing , Du Jiangbo , Xu Lin , Hu Zhibin 
Published: October 2019

AbstractAssociations between telomere length and cancer risk have been investigated in many epidemiological studies, but the results are controversial. These associations may be biased by reverse causation or confounded by environmental exposures. To avoid potential biases, we used Mendelian randomization method to evaluate whether TL is the causal risk factor for lung cancer. We conducted Mendelian randomization analysis in two published East Asian GWAS studies (7127 cases and 6818 controls). We used both weighted genetic risk score and inverse‐variance weighting method to estimate the relationship between TL and lung cancer risk. Nonlinear test also used to detect potential association trends. We observed that increased weight GRS was associated with increased risk of lung cancer (OR = 2.25, 95%CI: 1.81‐2.78, P = 1.18 × 10−13). In different subtypes, weight GRS was significantly associated with lung adenocarcinoma risk (OR = 2.69, 95% CI: 2.11‐3.42, P = 7.20 × 10−16); while lung squamous cell carcinoma showed a marginal association (OR = 1.45, 95% CI = 1.01‐2.10, P = .047). Nonlinear analysis suggested a log‐linear dose‐response relationship between increased weight GRS and lung cancer risk. Our results indicated that longer TL increases lung cancer risk. Those biological mechanisms changes caused by long TL may play an important role in lung carcinogenesis.
Climate change and invasion may synergistically affect native plant reproduction
Authors: Giejsztowt Justyna , Classen Aimée T. , Deslippe Julie R. 
Published: October 2019

AbstractGlobal change drivers can interact in synergistic ways, yet the interactive effect of global change drivers, such as climatic warming and species invasions, on plant pollination are poorly represented in experimental studies. We paired manipulative experiments to probe two mechanistic pathways through which plant invasion and warming may alter phenology and reproduction of native plant species. In the first, we tested how experimental warming (+1.7°C) modulated flowering phenology and how this affected flowering overlap between a native plant (Dracophyllum subulatum) and an invasive plant (Calluna vulgaris L.). In the second experiment, we explored how variation in the ratio of native to invasive flowers, and the overall quantity of resources in a floral patch, affected the reproduction of the native species. We hypothesized that the flowering overlap of native and invasive plants would be altered by warming, given that invading plants typically exhibit greater phenological plasticity than native plants. Further, we hypothesized that pollination of native plant flowers would decrease in floral patches dominated by invasive plant flowers, but that this effect would depend on total floral density in the patch. As predicted, the invasive plant had a stronger phenological response to experimental warming than the native plant, resulting in increased flowering overlap between the native the invasive plants. There was a four‐fold increase in the number of native flowers co‐flowering with high densities of invasive flowers suggesting native plant competition for pollinators with invasive plants under a warmed climate. In the second experiment, we found depressed seed masses of the native species in high density floral patches that were dominated by invasive flowers relative to high density floral patches dominated by native flowers. At low floral densities, seed mass of native plants was unaffected by invasion. Together, these results demonstrate that by increasing their phenological overlap, warming may enhance the magnitude of existing competition for pollination exerted by an invasive plant on a native plant, particularly in plant patches with high floral density. Our results illustrate a novel pathway through which global change drivers can operate synergistically to alter an important ecosystem service: pollination.
Assessment of Vibrational Spectroscopy Performance in Geographical Identification of Virgin Olive Oils: A World Level Study
Authors: Tena Noelia , Aparicio Ramón , Baeten Vincent , García‐González Diego Luis , Fernández‐Pierna Juan Antonio 
Published: October 2019

AbstractIn order to guarantee food integrity, testing methods should also include the tools needed to verify the geographical origin described on the label. In the particular case of virgin olive oil (VOO), regulatory bodies have yet to establish a standard for geographical identification. This manuscript describes a procedure based on Raman spectroscopy to identify the provenance of these oils based on a classification criterion (European vs non‐European VOOs). The sample collection is considered a relevant step in which multiple factors are taken into account (cultivar distribution, complexity of production in each location, new agricultural practices, and new/old cultivars). A total of 78 virgin olive oils collected around the world allow checking the classification accuracy of the model for identifying sample origin. The PLS‐model built around the Raman spectroscopic data is validated with a blind set of samples, and the results are evaluated in terms of false negative and false positive quality parameters. This study provides an analytical application to detect mislabeling and fraudulent practices related to the geographical provenance of virgin olive oils declared on the labels.Practical Applications: The results of this study provide a robust mathematical model to assess the origin of virgin olive oils (EU vs non‐EU) based on spectroscopic data. Nowadays, the extensive knowledge of olive oil chemical composition has proven that this composition varies according to pedoclimatic conditions, while non‐targeted methods can be proposed in geographical traceability for their ability to analyze the chemical profile of samples. However, it was deemed necessary to conduct a study through a collaborative work initiative. Thus, this study provides a strict evaluation of Raman spectroscopy through a defined strategy for evaluating non‐targeted methods for geographical identification.
The voltage‐gated calcium channel CaV1.2 promotes adult oligodendrocyte progenitor cell survival in the mouse corpus callosum but not motor cortex
Authors: Pitman Kimberley A. , Ricci Raphael , Gasperini Robert , Beasley Shannon , Pavez Macarena , Charlesworth Jac , Foa Lisa , Young Kaylene M. 
Published: October 2019

AbstractThroughout life, oligodendrocyte progenitor cells (OPCs) proliferate and differentiate into myelinating oligodendrocytes. OPCs express cell surface receptors and channels that allow them to detect and respond to neuronal activity, including voltage‐gated calcium channel (VGCC)s. The major L‐type VGCC expressed by developmental OPCs, CaV1.2, regulates their differentiation. However, it is unclear whether CaV1.2 similarly influences OPC behavior in the healthy adult central nervous system (CNS). To examine the role of CaV1.2 in adulthood, we conditionally deleted this channel from OPCs by administering tamoxifen to P60 Cacna1c
fl/fl (control) and Pdgfrα‐CreER:: Cacna1c
fl/fl (CaV1.2‐deleted) mice. Whole cell patch clamp analysis revealed that CaV1.2 deletion reduced L‐type voltage‐gated calcium entry into adult OPCs by ~60%, confirming that it remains the major L‐type VGCC expressed by OPCs in adulthood. The conditional deletion of CaV1.2 from adult OPCs significantly increased their proliferation but did not affect the number of new oligodendrocytes produced or influence the length or number of internodes they elaborated. Unexpectedly, CaV1.2 deletion resulted in the dramatic loss of OPCs from the corpus callosum, such that 7 days after tamoxifen administration CaV1.2‐deleted mice had an OPC density ~42% that of control mice. OPC density recovered within 2 weeks of CaV1.2 deletion, as the lost OPCs were replaced by surviving CaV1.2‐deleted OPCs. As OPC density was not affected in the motor cortex or spinal cord, we conclude that calcium entry through CaV1.2 is a critical survival signal for a subpopulation of callosal OPCs but not for all OPCs in the mature CNS.