bluuebunny/crossref_metadata_2025_split huggingface dataset:
A framework integrating corporate social responsibility for marketing architectural design firms in developing countries
Authors: Othman Ayman Ahmed Ezzat , Hafez Mai Gamal 
Published: August 2019

Purpose
This paper aims to develop a framework based on corporate social responsibility (CSR) as a novel approach for marketing architectural design firms (ADFs) in developing countries.

Design/methodology/approach
To achieve this aim, a research strategy consists of literature review and survey questionnaire is designed to accomplish four objectives: first, to examine the concepts of marketing and CSR in construction; second, to investigate the perception and application of CSR as a marketing tool for ADFs in developing countries; third, to develop a framework based on CSR as an approach for marketing ADFs in developing countries; and finally, to outline research conclusions and recommendations useful to government, ADFs and future research.

Findings
The research highlighted the inefficiency of current marketing strategies in developing countries due to lack of considering community needs, using incomprehensible technical language in communication with clients and misrepresenting the calibers of ADFs. ADFs believe that CSR can play a role in increasing their marketability. This requires governmental involvement and overcoming the barriers of adopting CSR.

Originality/value
This paper proposed a framework based on CSR as a novel approach for marketing ADFs in developing countries. This ideology has received scant attention in construction literature. The proposed framework represents a synthesis that is novel and creative in thought and adds value to the original body of knowledge in a manner that has not previously occurred.
Open-ended real estate funds: from flows to property
Authors: Baranyai Eszter 
Published: August 2019

PurposeThe purpose of this paper is to uncover the relationship between flows and real estate investment at open-ended real estate funds (OEREFs).Design/methodology/approachThe study employs fixed-effects panel regressions, relying on data from the Hungarian fund managers’ trade association. First, the effect of lagged flows on allocation to real estate is assessed. Second, the paper studies how this relationship changes as the cyclical position of CRE market advances using two proxies.FindingsFlows are found to affect funds’ real estate holdings if they occurred 12–18 months earlier. Inflows (outflows) in the preceding six months demonstrably lower (increase) funds’ real estate holdings ratio. Beyond this relationship, findings do not suggest that less funds are channelled to real estate as “CRE heat” intensifies.Practical implicationsIn an environment marked by strong cash inflows, the investment lag can translate into a significant drop in funds’ exposure to real estate. The share of real estate at Hungarian funds in the sample, for example, fell from 79 to 50 per cent on average over the period of 2011–2017. Measures designed to limit inflows are in the interest of those existing investors who wish to avoid a dilution of the core investment strategy.Originality/valueThe paper adds to the literature on OEREFs which has been particularly scarce on liquidity transformation during non-crisis times and on non-German funds.
The effect of process parameters on the residual stress of selective laser melted Inconel 718 thin-walled part
Authors: Chen Changpeng , Yin Jie , Zhu Haihong , Zeng Xiaoyan , Wang Guoqing , Ke Linda , Zhu Junjie , Chang Shijie 
Published: August 2019

Purpose
High residual stress caused by the high temperature gradient brings undesired effects such as shrinkage and cracking in selective laser melting (SLM). The purpose of this study is to predict the residual stress distribution and the effect of process parameters on the residual stress of selective laser melted (SLMed) Inconel 718 thin-walled part.

Design/methodology/approach
A three-dimensional (3D) indirect sequentially coupled thermal–mechanical finite element model was developed to predict the residual stress distribution of SLMed Inconel 718 thin-walled part. The material properties dependent on temperature were taken into account in both thermal and mechanical analyses, and the thermal elastic–plastic behavior of the material was also considered.

Findings
The residual stress changes from compressive stress to tensile stress along the deposition direction, and the residual stress increases with the deposition height. The maximum stress occurs at both ends of the interface between the part and substrate, while the second largest stress occurs near the top center of the part. The residual stress increases with the laser power, with the maximum equivalent stress increasing by 21.79 per cent as the laser power increases from 250 to 450 W. The residual stress decreases with an increase in scan speed with a reduction in the maximum equivalent stress of 13.67 per cent, as the scan speed increases from 500 to 1,000 mm/s. The residual stress decreases with an increase in layer thickness, and the maximum equivalent stress reduces by 33.12 per cent as the layer thickness increases from 20 to 60µm.

Originality/value
The residual stress distribution and effect of process parameters on the residual stress of SLMed Inconel 718 thin-walled part are investigated in detail. This study provides a better understanding of the residual stress in SLM and constructive guidance for process parameters optimization.
Steps towards a CSR binding paradigm
Authors: Masson Léna 
Published: August 2019

Purpose
The purpose of this paper is to pursue the dialogue on the global firms’ regulation vis-à-vis human rights and labor standards in developing countries.

Design/methodology/approach
Locke’s book The Promise and Limits of Private Power is analyzed and discussed with respect to more recent global regulation literature and mechanisms.

Findings
Locke advocates that private voluntary regulation has to be combined with local laws in developing countries to fully enforce labor standards and workers’ rights. In light of recent changes, the interesting model proposed by Locke shows some weaknesses.

Originality/value
To enforce labor standards and workers’ rights in developing countries, the author argue that governments in developed countries need to be seen as major players in multinational corporations (MNCs) regulations. But above all, the economic model needs to be questioned.
Benefits, Challenges, and Opportunities of Conducting a Collaborative Research Course in an International University Partnership: A Study Case Between Kansas State University and Tallinn University of Technology
Authors: Adriana Lezama‐Solano , Mauricio Castro , Delores Chambers , Loreida Timberg , Kadri Koppel , Edgar Chambers , Yu Huizi 
Published: August 2019

AbstractA globalized world requires research to transcend geographical boundaries; this includes training students in international collaborative research. The purpose of this project was to identify the benefits, opportunities, and challenges of students from two universities (Kansas State Univ. and Tallin Univ. of Technology) working on an international research project together. For this purpose, six graduate students from the Center for Sensory Analysis and Consumer Behavior, Kansas State Univ., partnered with 20 Food Science major students from a Product Development class at Tallinn Univ. of Technology. Students worked together by distance in a partnership developing a rye bread sensory lexicon for systematically understanding the sensory properties of this product category, conducting Landscape analysis by using sensory mapping techniques on rye bread products from Northeast Europe for capturing the market complexity and to identify opportunity for new product development and new products concepts. Students from Kansas then went to Estonia for further meetings. After the trip, students and professors were asked for their feedback. Results showed that students identify learning food trends from another country as the main benefit of their international collaboration, followed by intercultural skills and knowledge transfer. Language and difference in time zones, as well as educational backgrounds, were identified by students as the main challenges of the collaboration. When US students were asked to rate the learning outcomes stated in the syllabus, understanding the cultural characteristics of Estonia was the one scored highest. Professors mentioned this opportunity is unique because it gives a cultural component programs usually not only an offer and a chance to develop time management skills by working across divergent time zones, but also to practice options for managing language barriers. This project shows that it is possible to setup a partnership between students across different countries and have a positive outcome that includes unique learning experiences for students; especially in terms of time and project management.
Partnerships and production: Agriculture and polygyny in Tanzanian households
Authors: Damon Amy L. , McCarthy Aine Seitz 
Published: August 2019

AbstractWomen make important contributions to household food production in sub‐Saharan Africa. Women's agricultural productivity is often reduced, however, by inefficient intrahousehold allocation of agricultural resources. Complex marital structures found in polygynous households may complicate resource allocation. Using three waves of the Tanzania Living Standards Measurement Survey–Integrated Survey on Agriculture, we measure the effect of the marital structure, wife position, and plot management on agricultural productivity and input allocations. We find evidence of cooperation within polygynous households. Plots managed by husbands and wives in polygynous households produce more valuable crops, have higher yields, and are more likely to use fertilizer than their monogamous counterparts. Within polygynous households, we observe that plots jointly managed by husbands, first wives, and second wives (together) have significantly more family labor than plots managed by husbands and first wives. This result may provide evidence of different production technologies across plot managers within the same households.
The impact of uterine artery embolization on ovarian reserve: A systematic review and meta‐analysis
Authors: El Shamy Tarek , Amer Saad A. K. , Mohamed Ahmed A. , James Cathryn , Jayaprakasan Kannamannadiar 
Published: August 2019

AbstractIntroductionUterine artery embolization (UAE) has been gaining increasing popularity as an effective and minimally invasive treatment for uterine fibroids. However, there has been growing concern over the risk of unintended embolization of the utero‐ovarian circulation, leading to reduction of ovarian blood supply with subsequent impairment of ovarian reserve. The purpose of this study was to investigate the impact of UAE on circulating anti‐Müllerian hormone (AMH) and other markers of ovarian reserve.Material and methodsThis meta‐analysis included all published cohort, cross‐sectional and case‐control studies, as well as randomized trials that investigated the impact of UAE on circulating AMH. Data sources included MEDLINE, EMBASE, Dynamed Plus, ScienceDirect, TRIP database, ClinicalTrials.gov and the Cochrane Library from January 2000 to June 2019. All identified articles were screened, and articles were selected based on the inclusion and exclusion criteria. AMH and other data were extracted from the eligible articles and entered into RevMan software to calculate the weighted mean difference between pre‐ and post‐embolization values. PROSPERO registration number: CRD42017082615.ResultsThis review included 3 cohort and 3 case‐control studies (n = 353). The duration of follow up after UAE ranged between 3 and 12 months. Overall pooled analysis of all studies showed no significant effect of UAE on serum AMH levels (weighted mean difference –0.58 ng/mL; 95% CI –1.5 to 0.36, I2 = 95%). Subgroup analysis according to age of participants (under and over 40 years) and according to follow‐up duration (3, 6 and 12 months) showed no significant change in post‐embolization circulating AMH. Pooled analysis of serum follicle‐stimulating hormone (FSH) concentrations (4 studies, n = 248) revealed no statistically significant change after UAE (weighted mean difference 4.32; 95% CI –0.53 to 9.17; I2 = 95%). Analysis of 2 studies (n = 62) measuring antral follicle count showed a significant decline at 3‐month follow up (weighted mean difference –3.28; 95% CI –5.62 to –0.93; I2 = 94%).ConclusionsUterine artery embolization for uterine fibroids does not seem to affect ovarian reserve as measured by serum concentrations of AMH and FSH.
Pathologic placental lesions in early and late fetal growth restriction
Authors: Spinillo Arsenio , Gardella Barbara , Adamo Laura , Muscettola Giulia , Fiandrino Giacomo , Cesari Stefania 
Published: August 2019

AbstractIntroductionThe purpose of the study was to evaluate the differences in individual histopathologic placental lesions in pregnancies complicated by early‐onset (<32 weeks at diagnosis) and late‐onset (≥32 weeks at diagnosis) fetal growth restriction (FGR).Material and methodsA cohort study of 440 singleton pregnancies complicated by FGR, diagnosed according to standard ultrasonographic criteria, followed up and delivered at the same institution between 2010 and 2016. Placental lesions were classified according to the Amsterdam Placental Workshop Consensus Criteria. Pathologic examination of placentas from 113 healthy singleton term pregnancies served as controls. Binary and multinomial logistic regression models were used to evaluate the independent association of placental lesions with the type of FGR.ResultsIn our cohort the prevalences of early and late FGR were 37.3% (164/440) and 62.7% (276/440), respectively. The overall rates of preeclampsia (69/164 vs 59/276, P < 0.01) and absent/reversed umbilical artery pulsatility indices (61/164 vs 14/276, P < 0.001) were higher among early FGR than late FGR. Placental characteristics from early and late FGR pregnancies differed mainly in regard to maternal vascular malperfusion scores rather than fetal scores, with preeclampsia found to be a cofactor modulating the rates and severity of associated lesions. In the binary logistic analysis, recent infarcts (OR 2.44, 95% CI 1.2‐5), distal villous hypoplasia (OR 1.8, 95% CI 1.0‐3.2), atherosis (OR 2.71, 95% CI 1.35‐5.47), persistent endovascular trophoblasts (OR 1.67, 95% CI 1.03‐2.7), and a reduced fetal/placental weight score (OR 0.27, 95% CI 0.2‐0.38) were independently associated with an increased likelihood of early FGR compared with late FGR. The sensitivity, specificity, and area under the curve of the model were 60% (95% CI 51.2‐66.2), 89.1% (95% CI 84.9‐92.3), and 0.81 (95% CI 0.77‐0.85), respectively, suggesting a fair to good predictive value.ConclusionsIndividual placental lesions suggestive of increased rates of ischemia, defective remodeling of spiral arteries, peripheral hypoxia interfering with villus development, and reduced placental efficiency were significantly more common in early FGR than late FGR.
Scaffolding design thinking in online STEM preservice teacher training
Authors: Wu Bian , Hu Yiling , Wang Minhong 
Published: August 2019

AbstractDespite growing awareness of the importance of incorporating integrated science, technology, engineering and mathematics (STEM) learning into K‐12 education, formal classroom implementation still faces obstacles. Teachers lack the knowledge and skills, especially design‐thinking competence, required to design an interdisciplinary STEM curriculum. The goal of this study was to investigate different scaffolding modes that may influence the design‐thinking competence development of STEM teachers. Twenty‐four preservice teachers participated in this study, which was carried out in an online STEM preservice teacher training environment. The participants were assigned to six groups of two cohorts. Each group designed a STEM learning module. To support their online design meetings, the three groups from the static scaffolding cohort (SSC) received pre‐defined guiding questions, while the other three groups from the adaptive scaffolding cohort (ASC) received contingent scaffolding from a human tutor. The Log data on the participants’ conversations in the design meetings were collected and analysed using the epistemic network analysis (ENA) approach. The results revealed that the SSC and ASC had divergent design‐thinking development trajectories and established distinct design‐thinking patterns. Conversation analysis of the two cohorts confirmed the findings of the ENA analysis and provided evidence that the two scaffolding modes can help address challenges to collaborative STEM learning design and cultivate design‐thinking competence from different perspectives.
Practitioner NotesWhat is already known about this topic

Integrated and interdisciplinary STEM curriculum should be incorporated into K‐12 education.
Teachers lack the design‐thinking competence required to design an integrated and interdisciplinary STEM curriculum.
What this paper adds

Static scaffolding and adaptive scaffolding help STEM preservice teachers to develop process‐oriented and result‐oriented design‐thinking patterns, respectively.
STEM preservice teachers present divergent design‐thinking development trajectories during collaborative STEM learning design under these two scaffolding modes.
Implications for practice and/or policy

Integrated STEM learning design should leverage the complexity in the design process and creativity in the design solutions.
Different scaffolding modes can complement each other in support of design‐thinking competence development in collaborative STEM learning design practice.
Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function
Authors: McBrinn Rachel C. , Fraser Joanna , Hope Anthony G. , Gray David W. , Barratt Christopher L.R. , Martins da Silva Sarah J. , Brown Sean G. 
Published: August 2019

Background and PurposeAsthenozoospermia is a leading cause of male infertility, but development of pharmacological agents to improve sperm motility is hindered by the lack of effective screening platforms and knowledge of suitable molecular targets. We have demonstrated that a high‐throughput screening (HTS) strategy and established in vitro tests can identify and characterise compounds that improve sperm motility. Here, we applied HTS to identify new compounds from a novel small molecule library that increase intracellular calcium ([Ca2+]i), promote human sperm cell motility, and systematically determine the mechanism of action.Experimental ApproachA validated HTS fluorometric [Ca2+]i assay was used to screen an in‐house library of compounds. Trequinsin hydrochloride (a PDE3 inhibitor) was selected for detailed molecular (plate reader assays, electrophysiology, and cyclic nucleotide measurement) and functional (motility and acrosome reaction) testing in sperm from healthy volunteer donors and, where possible, patients.Key ResultsFluorometric assays identified trequinsin as an efficacious agonist of [Ca2+]i, although less potent than progesterone. Functionally, trequinsin significantly increased cell hyperactivation and penetration into viscous medium in all donor sperm samples and cell hyperactivation in 22/25 (88%) patient sperm samples. Trequinsin‐induced [Ca2+]i responses were cross‐desensitised consistently by PGE1 but not progesterone. Whole‐cell patch clamp electrophysiology confirmed that trequinsin activated CatSper and partly inhibited potassium channel activity. Trequinsin also increased intracellular cGMP.Conclusion and ImplicationsTrequinsin exhibits a novel pharmacological profile in human sperm and may be a suitable lead compound for the development of new agents to improve patient sperm function and fertilisation potential.
Body mass index and risk of sick leave: A systematic review and meta‐analysis
Authors: Amiri Sohrab , Behnezhad Sepideh 
Published: August 2019

SummaryBody mass index (BMI) is related to different health dimensions and can be a risk factor for diseases. Our objective was to systematically review and meta‐analysis the association BMI and the risk of sick leave. Four databases were searched for articles until late December 2018 and the results of the studies were extracted and combined using random effects methods. Several sub‐group analyses were conducted as well as bias of publication were measured. A total of 23 longitudinal studies entered into meta‐analysis. BMI ≥ 25 was a risk factor for sick leave; the risk ratio (RR) is equal to 1.20 with confidence interval (CI): 1.14 to 1.28. In the overweight, this result was achieved: RR = 1.09 and CI = 1.04 to 1.15 (P = 0.001) and in the obesity, RR = 1.30 and CI = 1.19 to 1.42 (P < 0.001). In both men and women, overweight and obesity were both a risk factor for sick leave. A high BMI is a risk factor that threatens health in different dimensions and therefore, overweight/obesity prevention and treatment should be given increasing attention. This will reduce the burden of illness and its consequences.
The P429L loss of function mutation of the human glycine transporter 2 associated with hyperekplexia
Authors: Kitzenmaier Alexandra , Schaefer Natascha , Kasaragod Vikram Babu , Polster Tilman , Hantschmann Ralph , Schindelin Hermann , Villmann Carmen 
Published: August 2019

AbstractGlycine transporter 2 (GlyT2) mutations across the entire sequence have been shown to represent the presynaptic component of the neurological disease hyperekplexia. Dominant, recessive and compound heterozygous mutations have been identified, most of them leading to impaired glycine uptake. Here, we identified a novel loss of function mutation of the GlyT2 resulting from an amino acid exchange of proline 429 to leucine in a family with both parents being heterozygous carriers. A homozygous child suffered from severe neuromotor deficits. We characterised the GlyT2P429L variant at the molecular, cellular and protein level. Functionality was determined by glycine uptake assays. Homology modelling revealed that the mutation localises to α‐helix 5, presumably disrupting the integrity of this α‐helix. GlyT2P429L shows protein trafficking through various intracellular compartments to the cellular surface. However, the protein expression at the whole cell level was significantly reduced. Although present at the cellular surface, GlyT2P429L demonstrated a loss of protein function. Coexpression of the mutant with the wild‐type protein, reflecting the situation in the parents, did not affect transporter function, thus explaining their non‐symptomatic phenotype. Nevertheless, when the mutant was expressed in excess compared with the wild‐type protein, glycine uptake was significantly reduced. Thus, these data demonstrate that the proline residue at position 429 is structurally important for the correct formation of α‐helix 5. The failure in functionality of the mutated GlyT2 is most probably due to structural changes localised in close proximity to the sodium‐binding site of the transporter.