bluuebunny/crossref_metadata_2025_split huggingface dataset:
SYPHILIS;
Authors: Ashfaq Ahsan , SALDERA KAUSAR ABBAS , EJAZ AYESHA , MEMON NOOR-UN NISA , RASHID HINA , IQBAL BEENISH 
Published: March 2019

Objectives: To assess serum Neopterin levels in blood donors of local population and to study its relationship with transfusion transmitted infections (TTIs) including syphilis. Study Design: Descriptive cross-sectional study. Place and Duration of Study: This study was carried out in the Department of Physiology LNMC in collaboration with Basic Medical Sciences Institute, (BMSI), and Jinnah Post Graduate Medical Centre (J.P.M.C.) Karachi, from Jan to July 2015.”Methods: Total 174 blood donors were included in the study through random sampling technique. They were screen through the standard procedures used for screening at the JPMC blood bank for WHO recommended diseases. Neopterin was estimated using ELISA. Data analysis was performed using SPSS version 21. Chi square and ANOVA were applied at a confidence level of 95%.”Results: Neopterin level in the sera of syphilis positive blood donors was 5.86 ± 0.78 nmol/l which was within normal range below the cutoff value of 10 nmol/l. Neopterin content in the serum of blood donors who were negative for transfusion transmitted infections was 6.23± 2.19 nmol/l as compared to blood donors testing positive for transfusion transmitted viral infections showing high Neopterin level of 15.10 ± 4.93 nmol/l. (P value 0.001).”Conclusion: Neopterin levels were found to be within normal limits in blood donors testing positive for syphilis However in blood donors with transfusion transmitted viral infections serum neopterin levels were elevated.
Hunting Tourism Map of Wild Goat: Antalya District
Authors: SÜEL Halil , ÜNAL Yasin , ÖZDEMİR Serkan , KOCA Ahmet 
Published: March 2019

The
wild goat (Capra aegagrus) has a very widespread area in our Turkey and is an
important species in terms of hunting tourism. Every year, inventory studies
are regularly carried out in all areas where these species have distributed in
Turkey. Native and foreign hunters are allowed to hunting these species by
giving certain quota determined for each year and thus economic income is
provided to the country. Generally, in hunting tourism, male individuals older
than the age of 8 years are important. In this study, presence data matrix was
prepared by determining the areas where the individuals aged 8 years and above
have been located according to the counts made after hunting in Antalya region
in 2016. Slope, elevation, aspect, topographic position index and ruggedness
variables that are selected considering of
the biology of wild goat were use for modelling. These variables were
cut in local scale by using ArcGIS 10.2 software and each was prepared as a
layer in ascii format. The modelling process was carried out using MaxEnt
method that run via maximum entropy approach and use only presence data, and
Random Forest method that run via both presence and absence data. The Roc value
for MaxEnt was 0.852 and the Roc value for Random Forest method was 0.927. These
results show that the models obtained by both methods are valid. The maps
obtained by both models were intersected to determine the most suitable areas
for wild goats. The hunting tourism map of the wild goat was obtained by using
0.6 reference value for suitable areas on the map that was acquired using
intersect. And the map show that current and potential hunting areas were
determined. As a result, this map is very important in terms of being a guide
for hunting tourism in study area and being the first hunting tourism map of
wild goats.
The role of the CagA gene in the occurrence of the inflammatory response of the gastric mucosa in patients with chronic Helicobacter pylori-associated gastritis
Authors: Vernigorodskiy S.V. , Sukhan D.S. 
Published: March 2019

Currently, Helicobacter pylori infection (H. pylori) is recognized as one of the most important risk factors for gastrocarcinogenesis. It is known that this infection does not directly cause neoplastic changes in the gastric mucosa, and this is due to a number of consecutive events due to the long persistence of the pathogen in the human body. The initial stage of this cascade, of course, is the inflammatory response, due to the body’s ability to adapt to extraneous infection, which is the inevitable result of the interaction of H. pylori with cells of the gastric epithelium. This direct damaging effect is enhanced by the production of vacuolating cytotoxin and the release of products of the cytotoxin-associated CagA gene, which, at a pathomorphological level, is manifested by inflammatory infiltration of the gastric mucosa (GM) to some extent. On the relationship between the degree of contamination and the activity of the inflammation of the GM in people infected with the CagA strain, today there are different, often conflicting opinions, which is why in this work we set the goal of establishing the relationship between the nature of the inflammatory response and the presence of the CagA gene in H. pylori- infected patients. The purpose of the study is to determinate the relationship between the nature of the inflammatory response and the genetic features of the H. pylori strain (CagA genotype).We examined 365 patients, among whom 40 people were included in the control group (18 women and 22 men, whose average age was 45,33±15,46 and 42,82±12,31, respectively) without any gastroenterological pathology in the anamnesis , patients with chronic non-atrophic gastritis (188 people) and chronic atrophic gastritis (137 people). A close relationship was established between the presence of the CagA gene, activity and the degree of contamination for chronic non-atrophic gastritis: for a low degree of contamination, Fisher’s exact test was = 0.002, p<0.05, for a moderate degree - 0.012, p<0.05, for a high degree - 0,012, p<0.05. Accordingly, in chronic atrophic gastritis: for a low degree of contamination Fisher’s exact test = 0.011, p<0.05, for a moderate degree - 0.003, p<0.05, for a high degree - 0.001, p<0.05. There is also a close relationship between the degree of contamination and the activity of chronic gastritis: in patients with a high degree of contamination, CG activity was determined, as a rule, for stage 2-3. In our study, the inflammatory response depended on the presence or absence of the H. pylori strain in the patient, which contains the CagA genotype, which, in our opinion, plays a key role in triggering a cascade of inflammatory changes in the GM and progression of chronic gastritis.
Features of total body sizes and anthropometric torso sizes in female volleyball players of mesomorphic somatotype
Authors: Sarafinyuk L.A. , Fomina L.V. , Khavtur V.O. , Fedoniuk L.Ia. , Khapitska O.P. , Stefanenko I.S. 
Published: March 2019

Determination of constitutional parameters that are inherent in highly skilled athletes of a particular sport can serve as reliable predictive markers during sport selection. But the last time an indisputable fact is the somatotypological conditionality of individual sizes that characterize the external structure of the body, and the visceral structures of the organism. The purpose of the work is to establish differences in the anthropometric dimensions between young women volleyball players of high level of athletic skill and non-sports young women belonging to the mesomorphic somatotype. On the base of the research center of the National Pirogov Memorial Medical University, we conducted an anthropo-somatotypological study of 127 female volleyball players of youth age (from 16 to 20 years) with a high level of athletic skill. Sports experience in all cases was greater than 3 years. From the database of research center of the National Pirogov Memorial Medical University was selected 140 practically healthy young women of the same age who were not engaged in sports. Anthropometric measurements were carried out using the method of V.V. Bunak (1941), somatotypological research – according to the estimated modification of the Heath-Carter method (1990). After the conducted somatotyping, it was found that 29 volleyball players and 33 non-sports young women belonged to the mesomorphic type of constitution. The analysis of the obtained results is carried out in the licensed package of Statistica 5.5 using nonparametric methods of evaluation of indicators. In the volleyball players of the mesomorphic somatotype, compared to young women who are not engaged in sports of the same constitutional type, we have found a significantly larger length of the body, the mass and area of the body surface, the height of the suprasternal, pubic, shoulder anthropometric points, chest cords, transverse mid and lower chest and sagittal middle-thigh diameters, intervertebral distance of the pelvis and its external conjugates. Relatively smaller in female volleyball players of mesomorphic type of physique was the thickness of the skin-fat folds under the shoulder blade. One can conclude that within the same somatotype there are significant changes in the anthropometric parameters, in particular total body and longitudinal, transverse, front and rear body dimensions, which is affected by the body of modern young women volleyball players with mesomorphic somatotype, under the influence of intensive loads.
Features of the thyroid gland structural components remodeling in the toxemia stage after experimental thermal injury
Authors: Koritskiy V.G. , Nebesna Z.M. 
Published: March 2019

Thermal injury causes severe structural and metabolic disturbances not only of the skin itself, but also of all organs and systems of the affected organism, is a manifestation of a complex symptom complex - a burn disease. Of particular importance in patients with burns are changes in the endocrine system. The aim of the study was to establish the microscopic and electron-microscopic reorganization of the components of the thyroid gland of animals after thermal damage on 14 day after experimental thermal injury. A III degree burn was applied under ketamine anesthesia with copper plates heated in boiled water to a temperature of 97-100°C. The size of the lesion area was 18-20% of the epilated surface of the body of rats. An experimental study of the structural components of the thyroid gland after a burn injury was performed on laboratory white male rats weighing 160-180 g. Rats euthanasia was performed after ketamine anesthesia by decapitation. In the experiment, the study of the microscopic and submicroscopic state of the follicles and hemocapillaries of the thyroid gland after thermal injury of the III degree. It has been established that in the toxemia stage after the application of the burn injury on 14 day (late toxemia stage), significant destructive and degenerative changes are found in the thyrocytes of the wall of the follicles and hemocapillaries, the organ acquires a macrofollicular structure. The height of thyrocytes decreases, the nuclei and organelles of cytoplasm are significantly damaged, the number and height of microvilli on their apical surface decreases, which negatively affects the cell's secretory cycle and transcapillary organ metabolic processes. The established destructive changes in the blood capillaries and thyrocytes of the follicles are the morphological manifestation of the suppression of the secretory activity of the thyroid gland during thermal injury and corresponds to the hypofunctional state of the organ.
Changes in the sizes of the kidney after contralateral nephrectomy in the experiment
Authors: Monastyrskyi V.M. 
Published: March 2019

The evaluation of renal measurements such as length, width and thickness, volume is important in the diagnosis and treatment of many renal disorders, since there is a close relationship between the sizes of the kidneys and its function. The purpose of the study was to establish and compare during the postoperative period changes in the mass and sizes of the kidney left after nephrectomy in the sexually mature male rats. An experimental study was carried out on 84 sexually mature white male rats weighing 178-194 grams. Animals were divided into two groups: control (42 rats) and experimental (42 rats). In the control group, the animals under ketamine anesthesia were followed by an abdominal cavity dilution, after which the abdominal wall was applied in a row. All animals of the experimental group performed surgical intervention – nephrectomy of the left kidney. The animals were withdrawn from the trial by intra-pleural administration of thiopental-sodium 50 mg/kg after 7, 14, 21, 30, 90 days after nephrectomy. Macroscopic evaluation and description of the kidneys of animals was performed after their removal. Their weight was determined on the laboratory scale of HLR-200 up to 0.1 mg, and the length, width and thickness of the organ were measured with the help of a caliper to an accuracy of 0.05 mm. Calculated the volume of the kidney. The statistical analysis of the obtained results was carried out using the program STATISTICA 5.5 using parametric methods for evaluating the results. It was established that the mass, length, width, thickness and volume of the kidney of animals in the experimental group, as compared with the control group, were statistically significantly higher in all terms of observation. The fraction of the growth of the width and thickness of the single kidney of animals in the experimental group compared with the control animals in the animals was statistically significantly greater than the proportion of kidney growth during the postoperative period. It was found that the largest increase in the mass and thickness of the kidney, as compared with the control group, was observed after 30 days of the postoperative period, and the greatest increase in the length and width of the kidney, as compared with the control group, was observed after 14 days of the postoperative period.
Proliferative features of diffuse astrocytic tumors Grade III-IV and their impact on the prognosis
Authors: Yakovtsova I.I. , Gavriliyuk A.O. , Chertenko T.M. 
Published: March 2019

Anaplastic astrocytoma and glioblastoma are malignant brain tumors with a poor prognosis. The aim of our study was the complex investigation of the factors, those influence their aggressive behavior and proliferation (Ki-67, EGFR, MMP-9, PR, р53, vascular network formation), and the evaluation of their prognostic impact. These data could be used for optimization of target therapy in different groups of patients with diffuse astrocytic tumors Grade III-IV. Our study included 30 patients who were put through brain surgery for the first time and were divided into two equal groups: 15 patients who experienced a recurrence within 1 year after the surgery (1st group) and 15 patients without recurrence within 1 year after the surgery (2nd group). Postoperative tumor materials were obtained in formalin-fixed, paraffin-embedded blocks. In addition, we investigated the case histories of these patients. The expression of Ki-67, EGFR, MMP-9, PR, р53, VEGF, and CD34 was evaluated with immunohistochemical testing. Chi-squared test, Mann-Whitney U and Kruskal-Wallis H tests were performed for comparison of quantitative parameters between groups. Spearman’s rank correlation coefficient was used for the measure of rank correlation between quantitative variables. Results of our study showed, that there was a tendency (Uemp=75,00; р>0.05) to higher proliferative index in the 1st group (18,29±3,44) compared to the 2nd group (16,57±3,09). EGFR expression was significantly higher in the 1st group (Uemp=70.50; p<0.05). Moreover, the higher EGFR expression was associated with higher MMP-9 expression (Uemp=7.500; p<0.01) and lower p53 expression (rs= –0.62, p<0.001). The higher MMP-9 expression was also associated with higher vascularization index (MVD(VEGF)/MVD(CD34)) (rs=0.43; p<0.05). Our data confirm the close connections of different factors of tumor aggressiveness and the presence of molecule-biological discrepancy in homogenous histologically, but heterogenous prognostically groups of tumors. This evidence may be used in future for better-personalized therapy of patients with diffuse astrocytic tumors Grade III-IV.
Evaluation of the Success Rate of Hysteroscopy and Endometrial Scratching in Cases of Repeated Implantation Failure: A Randomized Controlled Clinical Trial
Authors: Zahiri Ziba , Sarrafzadeh Yasaman , EhsanKazemNejad Leili , Sheibani Alireza 
Published: March 2019

Background: Endometrial reception is one of the most important factors in vitro fertilization (IVF) success rate. Many different methods have been suggested to enhance the rate of implantation in IVF\ intracytoplasmic sperm injection (ICSI) cycles. Endometrial injury, as an intentional trauma aimed at improving the fertility results, has gained significant popularity among women seeking pregnancy. This study was conducted to determine the success rate of hysteroscopy and scratching before microinjection in cases of repeated implantation failure. Materials and Methods: This prospective, randomized controlled trial consist of 228 women who were referred to the Al-Zahra Infertility clinic for fertility treatment with the history of failure in at least two ICSI cycles. The patients were divided into two groups. The first group was treated by hysteroscopy without intervention, while the second group underwent hysteroscopy and scratching in the luteal phase of the menstrual cycle prior to microinjection. The controlled ovulation stimulation method was performed in all patients using the antagonist method. The success was considered based on the observation of the fetal heart in ultrasound. Results: The success rate of hysteroscopy and scratching (41.5%) was higher compared to hysteroscopy alone (34.3%), but this difference was not statistically significant based on the Chi-square test (P=0.280). The rate of miscarriage in hysteroscopy plus scratching and hysteroscopy alone were 5.7% and 12.4%, respectively which were not statistically different (P=888). Furthermore, the effect of hysteroscopy and scratching on visualizing the fetal heart was not statistically different compared to hysteroscopy alone (P=0.223). Conclusion: The results showed that the success rate in hysteroscopy plus endometrial scratching was not significantly different from hysteroscopy. [GMJ. 2019;inpress:e1399]
PENGUKURAN GREENSHIP KAWASAN(BUILT PROJECT) VERSI 0.1 PADA KAWASAN WISATA BANDAR ECOPARK DI KABUPATEN BATANG
Authors: Ronim Azizah , Talidah Cita Iftinan 
Published: March 2019

Abstract: GREENSHIP neighborhood is an rating tool for disseminating and inspiring realization of sustainable areas. Benefits by applying GREENSHIP Neighborhood are: (1) Maintaining harmony and balance of environmental ecosystems, as well as improving quality of environment, (2) Minimizing adverse impacts of development on the environment, (3) Improving quality of microclimates, ease of achievement, security, and convenience pedestrian and (5) Maintaining a balance between needs and availability of resources in future. In case study of Bandar Ecopark which located in Bandar Subdistrict, Batang Regency is a recreational area with an ecotourism park that has a positive impact on environment. So it is interesting to study the extent of Greenship Region measurements that can be achieved in this region. Measurement method uses one of the 4 Greenship Region benchmarks, namely: (1) mixed use area, (2) commercial, (3) settlement and (4) industry. Results of the Greenship Region shows that Bandar Ecopark region has score 57 with quality 46% (of total value 124), with details: LEE (17), MAC (14), WMC (0), SWM (6 ), CWS (10), BAE (6) and IFD (4). Greenship neighborhood that generated is SILVER. To optimize rankings, it is necessary to add a number of means in each benchmark.Keyword: green architecture, ecotourism, greenship neighborhood.Abstrak: GREENSHIP Kawasan merupakan perangkat penilaian untuk menyebarkan dan menginspirasi dalam perwujudan kawasan yang berkelanjutan. Manfaat yang diperoleh dengan menerapkan GREENSHIP Kawasan yakni: (1) Menjaga keserasian dan keseimbangan ekosistem lingkungan, serta meningkatkan kualitas lingkungan kawasan, (2) Meminimalkan dampak buruk pembangunan terhadap lingkungan, (3) Meningkatkan kualitas iklim mikro, (4) Menerapkan asas keterhubungan, kemudahan pencapaian, keamanan, dan kenyamanan pada jalur pedestrian dan (5) Menjaga keseimbangan antara kebutuhan dan ketersediaan sumber daya di masa mendatang. Pada studi kasus kawasan wisata Bandar Ecopark yang terletak di Kecamatan Bandar, Kabupaten Batang merupakan kawasan wisata rekreasi air dengan daya tarik taman ekowisata yang berdampak positif bagi lingkungan. Sehingga menarik untuk dikaji sejauhmana pengukuran Greenship Kawasan yang dapat tercapai pada kawasan ini. Metode pengukuran menggunakan salah satu dari 4 tolok ukur Greenship Kawasan yaitu: (1) kawasan mixed use, (2) komersial, (3) pemukiman dan (4) industri. Hasil dari pengukuruan Greenship Kawasan menunjukkan bahwa kawasan wisata Bandar Ecopark dari total nilai keseluruhan maksimum sebesar 124, kawasan Bandar Ecopark mendapat nilai 57 dengan bobot 46% dengan rincian: LEE (17), MAC (14), WMC (0), SWM (6), CWS (10), BAE (6) dan IFD (4). Peringkat Greenship Kawasan yang dihasilkan adalah SILVER. Untuk mengoptimalkan peringkat maka perlu penambahan beberapa sarana di setiap tolok ukur.Kata kunci: green architecture, ekowisata, greenship kawasan
WALKABILITY DI KAWASAN TITIK NOL KILOMETER YOGYAKARTA MELALUI SIMULASI URBAN MODELLING INTERFACE (UMI)
Authors: Nugrahaini Fadhilla Tri 
Published: March 2019

Abstract: Sustainable city development considered as a way to create better environment for the society. Walkability needs to be encouraged to reduce emissions and increase energy efficiency. This paper highlights the walkability assessment in Titik Nol Kilometer Yogyakarta. The simulation using Urban Modelling Interface (UMI) evaluates that the walkscore is need to be increased. Keyword: Sustainable 1, Walkability 2, Walkscore 3 (Maks 3 Kata, ARIAL 10, spasi tunggal)Abstrak: Pengembangan kota berkelanjutan dinilai sebagai suatu langkah untuk menciptakan lingkungan yang baik bagi masyarakat. Kemudahan dalam berjalan kaki perlu didorong untuk mengurangi emisi dan meningkatkan efisiensi energy. Pengukuran nilai walkability di Titik Nol Kilometer Yogyakarta sebagai langkah awal untuk mempelajari tingkat keberlanjutan pada kawasan tersebut. Metode simulasi menggunakan Urban Modelling Interface menampilkan bahwa nilai walkscore pada kawasan tersebut belum ideal. Kata Kunci: Keberlanjutan1, Walkability 2, Walkscore 3 (Maks 3 Kata, ARIAL 10, spasi tunggal)
Development of the algorithm for the selection of a wind generator-based autonomous power supply system
Authors: Khlyupin P. A. , Ispulaeva G. N. 
Published: March 2019

Introduction: The co-authors provide an overview of the main types of wind turbines and power generators installed into wind energy devices, as well as advanced technological solutions. The co-authors have identified the principal strengths and weaknesses of existing wind power generators, if applied as alternative energy sources. The co-authors have proven the need to develop an algorithm for the selection of a wind generator-based autonomous power supply system in the course of designing windmill farms in Russia. Methods: The co-authors have analyzed several types of wind turbines and power generators. Results and discussions: The algorithm for the selection of a wind generator-based autonomous power supply system is presented as a first approximation. Conclusion: The emerging algorithm enables designers to develop an effective wind generator-based autonomous power supply system.