bluuebunny/crossref_metadata_2025_split huggingface dataset:
Síndrome de Capgras: una revisión breve
Authors: Strobbe-Barbat Mariella , Macedo-Orrego Luis , Cruzado Lizardo 
Published: April 2019

Los síndromes de falsa identificación, grupo de patologías neuropsiquiátricas, con las delusiones de falso reconocimiento como denominador común, incluyen, entre otros, al Síndrome de Capgras, caracterizado por la firme creencia, por parte del paciente, de que una persona cercana a él/ella, generalmente un familiar, ha sido sustituida por un “doble exacto” o “impostor”, describiendo la similitud física entre ambos; en pocos casos, tal creencia se extiende a animales domésticos e incluso a objetos inanimados. Un alto porcentaje de casos se asocia a un trastorno orgánico cerebral de base, especialmente demencias neurodegenerativas, pero también puede ocurrir en enfermedades psiquiátricas primarias, tales como esquizofrenia y trastornos esquizoafectivos o afectivos. La exploración neurobiológica plantea diferentes hipótesis explicativas del síndrome, entre ellas los modelos de desconexión visuoanatómico de Ellis y Young, de lateralización de Gainotti y de distribución de redes neuronales de Gobbini y Haxby. El falso reconocimiento puede dar lugar a conductas violentas del paciente contra las personas implicadas como supuestos “dobles”, especialmente en casos de pacientes varones, con enfermedad psiquiátrica de fondo (i.e., esquizofrenia paranoide), con antecedentes de consumo de sustancias psicoactivas o presencia concomitante de alucinaciones auditivas imperativas. No existe tratamiento específico para el Síndrome de Capgras, pero ciertamente el cuadro psiquiátrico subyacente debe ser manejado con fármacos antipsicóticos e incluso terapia electroconvulsiva.
Efeito da embalagem com atmosfera modificada na conservação do Brycon amazonicus
Authors: VIANA Adriana Pontes , INHAMUNS Antônio José , OLIVEIRA Pedro Roberto de , SOUZA Laíza Caroline Lobo de 
Published: April 2019

O matrinxã é muito apreciado na região amazônica, desta forma o aumento no tempo de vida útil comercial é fundamental. O objetivo deste trabalho foi avaliar a influência da Embalagem em Atmosfera Modificada í EAM, associada í­Â refrigeração para prolongar o tempo de armazenamento do matrinxã, Brycon amazonicus sob 2Â±1Â°C. As amostras embaladas em EAM com CO2 (100%); CO2/N2 (60/40%) e vácuo tiveram suas caracterí­­sticas fí­­sico-quí­­micas, microbiológicas e sensoriais avaliadas durante 35 dias de armazenamento. As amostras embaladas a vácuo apresentaram maior crescimento microbiano, mas mantiveram boa qualidade por aproximadamente, 17 dias de estocagem. As amostras tratadas com EAM CO2/N2 (60/40%) e CO2(100%) apresentaram boa qualidade por aproximadamente, 35 dias. O teste de aceitabilidade do produto cozido foi igual para os atributos sabor, odor e textura, exceto para aparência e cor, que foram melhores, com significí­¢ncia de 5%, nos tratamentos CO2/N2 (60/40%) e vácuo. O presente estudo mostrou que o tratamento em atmosfera modificada CO2/N2(60/40%) se destacou aos demais tratamentos sendo uma técnica promissora para estender a vida útil do matrinxã por até 35 dias sob refrigeração.
THE IMPACT OF LONG CANYON DESIGN AND WATERFRONT BARRIER BUILDINGS ON WIND VELOCITY IN A COASTAL AREA OF SELATPANJANG CITY
Authors: Rahman Boby , Dinapradipta Asri , Defiana Ima 
Published: April 2019

<p class="Abstract"><em>The increase of waterfront buildings’ height has an effect on wind distribution in the urban canyon. On the other hand, the distribution of wind is needed in providing thermal balance in urban environments, especially in urban waterfront coastal areas. This study aimed at observing and analyzing the effect of building height (H) on waterfront buildings and aspects of the length to width (L/W) ratio related to the length of the canyon design. The observation was focused on the wind speed distribution. The research was an experimental research using ENVI-met V3.1 software for simulation. The results indicated that short canyon (low L/W value) results in lower wind speed changes compared to that of long one (higher L/W value) at all altitude levels. The short canyons provided more stability in wind speed reduction. The 15 meters wide of canyon design contributed to the highest average wind speed. Overall, the existence of a barrier building would result in a negative area of air flow and create a calm area within the distance of ± 50 meters.</em></p><em></em>
The Ultrasound-guided Proximal Intercostal Block: Anatomical study and clinical correlation to analgesia for breast surgery
Authors: Zinbonyahgoon Nantthasorn , Luksanapruksa Panya , Piyaselakul Sitha , Pangthipampai Pawinee , Lohasammakul Suphalerk , Luansritisakul Choopong , Mali-ong Sunsanee , Sateantantikul Nawaporn , Chueaboonchai Theera , Vlassakov Kamen 
Published: April 2019

Abstract
Background:
The ultrasound-guided proximal intercostal block (PICB) is performed at the proximal intercostal space (ICS) between the internal intercostal membrane (IIM) and the endothoracic fascia/parietal pleura (EFPP) complex. Injectate spread may follow several routes and allow for multilevel trunk analgesia. The goal of this study was to examine the anatomical spread of large-volume PICB injections and its relevance to breast surgery analgesia.
Methods:
Fifteen two-level PICBs were performed in ten soft-embalmed cadavers. Radiographic contrast mixed with methylene blue was injected at the 2nd(15ml) and 4th(25ml) ICS, respectively. Fluoroscopy and dissection were performed to examine the injectate spread. Additionally, the medical records of 12 patients who had PICB for breast surgery were reviewed for documented dermatomal levels of clinical hypoesthesia. The records of twelve matched patients who had the same operations without PICB were reviewed to compare analgesia and opioid consumption.
Results:
Median contrast/dye spread was 4(2-8) and 3(2-5) vertebral segments by fluoroscopy and dissection respectively. Dissection revealed injectate spread to the adjacent paravertebral space, T3 (60%) and T5 (27%), and cranio-caudal spread along the endothoracic fascia (80%). Clinically, the median documented area of hypoesthesia was 5(4-7) dermatomes with 100% and 92% of the injections covering adjacent T3 and T5 dermatomes, respectively. The patients with PICB had significantly lower perioperative opioid consumption and trend towards lower pain scores.
Conclusions:
In this anatomical study, PICB at the 2nd and 4th ICS produced lateral spread along the corresponding intercostal space, medial spread to the adjacent paravertebral/epidural space and cranio-caudal spread along the endothoracic fascial plane. Clinically, combined PICBs at the same levels resulted in consistent segmental chest wall analgesia and reduction in perioperative opioid consumption after breast surgery. The incomplete overlap between paravertebral spread in the anatomical study and area of hypoesthesia in our clinical findings, suggests that additional non-paravertebral routes of injectate distribution, such as the endothoracic fascial plane, may play important clinical role in the multi-level coverage provided by this block technique.
Longitudinal observation of OCT imaging is a valuable tool to monitor primary vitreoretinal lymphoma treated with intravitreal injections of methotrexate
Authors: Zhao Huiying , Wang Xiaona , Mao Yu , Peng Xiaoyan 
Published: April 2019

Abstract
Background: Developing objective and repeatable indicators to evaluate the efficacy of PVRL treatment is important. The quantification of vitreous cells is a traditional criterion; however slight changes are difficult to ascertain. Spectral domain optical coherence tomography (SD-OCT) is objective, repeatable, and easily explained. The purpose of this study is to provide a longitudinal observation of OCT in PVRL treated with intravitreal injections of methotrexate (MTX) and to evaluate the utility of OCT in monitoringresponsiveness of PVRL to treatment. Methods: The medical records of patients with biopsy-positive PVRL attending our hospital between January 2016 and September 2017 who received intravitreal injections of MTX were included in this study. Pre- and posttreatment OCT images were reviewed independently by two researchers. Results: Of the 24 cases reviewed, 10 patients (18 eyes) were included. SD-OCT abnormalities at the initial visit included hyperreflective foci in the posterior vitreous (18/18), hyperreflective dots in the RPE (12/18), PEDs (detachment of retinal pigment epithelium) (9/18), hyperreflective band above the RPE (3/18), hyperreflectivity in the full thickness of the retina (8/18), and subretinal fluid (4/18). At one month after treatment, the subretinal fluid in cases with RD was absorbed, and subretinal fibrosis appeared. Other lesions were significantly reduced. At two months after treatment, the hyperreflective dots in the RPE, PEDs and subretinal fluid disappeared in 2 eyes, hyperreflectivity in the full thickness of the retina disappeared in 1 eye, and other abnormalities further improved. Additionally, retinal fibrosis was observed in 3 eyes. At nine months after treatment, all abnormalities observed at the first visit vanished. At the last visit, OCT showed subretinal fibrosis and in 3 eyes (16.7%), the disruption of outer retina in 9 eyes (50%) and thinning of the whole layer in 4 eyes (22.2%).Conclusions: Our observations reveal that characteristic OCT features in PVRL patients can reduce gradually and finally vanish with therapy. We propose that SD-OCT may be employed to monitor the responsiveness of PVRL to treatment, which may influence decision making in the management of this disease.
Meta-analysis of Corneal Biomechanical Effects after SMILE and FS-LASIK
Authors: Qin Jie , Fu Tingting , Tang Qi , Yang Lu , Chen Min 
Published: April 2019

Abstract
Background: To evaluate and compare corneal biomechanics after treatment of myopia using small-incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK).
Methods: We performed a meta-analysis and searched for reports concerning corneal biomechanics after SMILE and FS-LASIK using MEDLINE, EMbase, CNKI and the Cochrane Library. The analysis included corneal hysteresis (CH) and corneal resistance factor (CRF) before and 3 months after the surgery. The quality of the reports was evaluated using the Newcastle-Ottawa scale (NOS). Statistical analysis was performed using RevMan5.
Results: Only six studies with a total of 771 eyes were ultimately included in this meta-analysis, and the random effects model was adopted. The preoperative and three-month postoperative CH and CRF of SMILE and FS-LASIK were compared by the meta-analysis. No statistically significant difference was found in CH or CRF between the SMILE group and the FS-LASIK group before the surgery (WMD，-0.12; 95% CI，-0.31～0.06; P，0.19; WMD，-0.05; 95% CI，-0.29～0.19; P，0.69). There was no statistically significant difference in CH between the two surgical methods 3 months after the operation in the foreign group (WMD，0.19; 95% CI，-1.02～1.41; P，0.75) or in the Chinese group (WMD，0.13; 95% CI，-0.16～0.41; P，0.75). Likewise, no statistically significant difference was found in CRF between the two surgical methods in the foreign group 3 months after the operation (WMD，-0.11; 95% CI，-2.53～-2.31; P，0.93). Nevertheless, the difference in CRF between the two surgical methods was statistically significant in the Chinese group (WMD，0.26; 95% CI，0.06～0.47; P，0.01).
Concusion: This meta-analysis indicated that SMILE showed no significant postoperative advantage in CH in comparison with FS-LASIK. For CRF, SMILE exhibited no obvious postoperative advantage in comparison with FS-LASIK in the foreign group, whereas SMILE was superior to FS-LASIK in the Chinese group.
GALC mutations in Chinese patients with late-onset Krabbe disease: a case report
Authors: Zhuang Shunzhi , Kong Lingen , Li Caiming , Chen Likun , Zhang Tingting 
Published: April 2019

Abstract
Background: Krabbe disease (also known as globoid cell leukodystrophy) is an autosomal recessive neurodegenerative disorder caused by a deficiency of the enzyme -galactocerebrosidase (galactosylceramidase, GALC). The deficiency of GALC leads to accumulation of galactosylceramide and psychosine, the latter GALC substrate having a potential role in triggering demyelination. Typically, the disease has an infantile onset, with rapid deterioration in the first few months, leading to death before the age of 2 years. The late onset forms (late-infantile, juvenile, and adult forms) are rare with variable clinical outcomes, presenting spastic paraplegia as the main symptom.
Case presentation: We recruited a family with two affected individuals. The proband (Patient 1), a 25-year-old male, was presented with slow progressive spastic gait disturbance and vision loss, suffering since the 5th year of life. His elder sister (Patient 2), became wheelchair-bound and demented at the age of 22 years. Brain magnetic resonance imaging (MRI) showed increased signal intensity in the white matter along with the involvement of the bilateral corticospinal tracts. GALC deficiency was confirmed by biochemical analysis. DNA sequencing revealed two mutations (c.865G>C: p. G289R and c.136G>T: p. D46Y) in GALC. The clinical characteristics, brain MRI, biochemical and molecular findings led to the diagnosis of Krabbe disease.
Conclusion: Clinical and neuroimaged signs, positive enzymatic analysis and molecular data converged to definite diagnosis in this neurodegenerative disease.
Miller Fisher Syndrome presenting as unilateral abducens nerve palsy: A case report
Authors: Silva Neomal Sawanawadu Dilantha De , Singhapathirana Suranga , Silva Chintaka Eshan De 
Published: April 2019

Abstract
Background : Miller Fisher Syndrome usually presents with complete ophthalmoplegia, areflexia and ataxia. We present an unusual case which presented with unilateral abducens nerve palsy. Case presentation : A 51 year old female patient presented with a history of difficulty in walking and double vision for 1 week which started 2 weeks following an episode of acute gastroenteritis. She didn’t have any bladder bowel incontinence or difficulty in breathing. On examination there was left side abducens nerve palsy and bilateral significant dysmetria. Upper limb and lower limb power was 4/5 with global areflexia. There was no fatigability or sensory deficit. Higher cortical functions were intact with Glasgow Coma Scale of 15/15. Brain stem cerebro vascular accident, alcohol, toxin or drug mediated disease, myasthenia gravis, Bickerstaff encephalitis and Miller-Fisher syndrome were considered as possible differential diagnosis. There was no history of alcohol consumption or any exposure to drugs or toxins. Her Non contrast brain and MRI brain were normal. Nerve conduction study showed asymmetrical sensory motor and F wave abnormalities consistent with a Guillen-Barre Sydrome variant. Cerebro Spinal Fluid analysis showed albumino-cytological dissociation. These findings suggested the diagnosis of Miller-Fisher Syndrome. She was started on plasmaphareis. Her vital parameters, vital capacity and neurological deficit were closely monitored. With 5 cycles of plasmapharesis she made a complete neurological recovery and she was discharged on 16th day of admission. Conclusion: Miller Fisher Syndrome can present as unilateral abducens nerve palsy and early diagnosis and treatment leads to excellent functional outcome.
POSTERIOR C1-C2 FUSION FOR ATLANTOAXIAL ROTATORY FIXATION AFTER POSTERIOR FOSSA CRANIOTOMY IN A 4-YEAR-OLD: A CASE REPORT
Authors: Benites Vinicius Meldau , Cavalheiro Sergio 
Published: April 2019

Abstract
Study Design: Case report Objective: This study aimed to highlight that Atlantoaxial rotatory fixation (AARF) can be related to neurosurgery procedures in children with an afterwards demonstration of good results after halo-gravity traction and C1-C2 stabilization using the Harms technique. Summary of Background Data: AARF is characterized by dislocation or subluxation of the atlantoaxial joint, leading to a rotational deformity which may cause pain. Such a condition is mostly found in pediatric patients. Trauma, upper respiratory infections, surgery of the head and the neck, and even rheumatoid arthritis and Down syndrome have been designated as predisposing factors. It is important to note that in some cases AARF evolves with no apparent cause and to date, the choice of optimal surgical procedure should be carefully selected, considering the anatomical and bone conditions, as well as the surgeon’s experience with each technique. Methods: We report the first case related, in our knowledge, of a 4-year-old boy who presented atlantoaxial rotatory fixation after a posterior fossa craniotomy to treat a cerebellar astrocytoma. Results: At our medical facility, we diagnosed AARF by plain radiograph and CT image, and he was treated with continuous cranial traction for 14 days. Initially, we detected that he had no C1 posterior arch or C2 spinous process, so our choice was to perform Harms technique. Postoperatively, the patient was placed in a cervical collar for four weeks. At him 4-years postoperative follow-up, he was doing well and did not develop any complication. Conclusion: We call the attention to the fact of AARF can be developed after neurosurgical procedures. A surgical technique to be used in Atlantoaxial subluxation should be carefully select. In our case, Harms technique after cranial traction was an excellent option to correct and stabilize the abnormal neck position presented. However, further studies are required to determine the best technique to be used in the pediatric population.
Rainfall analysis for rain-fed farming in the Great Rift Valley Basins of Ethiopia
Authors: Ademe Fitih , Kibret Kibebew , Beyene Sheleme , Getinet Mezgebu , Mitike Gashaw 
Published: April 2019

AbstractRainfall is the most important source of water for crop production in Ethiopia. However, its temporal and spatial variability is leading to serious food shortages and insecurity in the country. This study was aimed at investigating the characteristics of selected agroclimatic variables over the great Rift Valley regions of Ethiopia. Long term (1981–2010) climate data were analyzed for 17 stations selected based on agroecology representation. Selected descriptors for climate variability and the Mann–Kendall trend test were employed. Onset, cessation, length of growing period (LGP), water requirement satisfaction index and dry spell occurrence during the growing period were determined. The results showed low to very high rainfall variability (14–35%), LGP (20–256 days) and dry spell probability (50–100%) during the main season. Significant (P ≤ 0.05) annual and seasonal rainfall trends were observed in some stations. The probability of occurrence of a dry spell during the seasons was found to be a challenge for most of the stations in the mid and low altitude areas of the basins. Consequently, seasonal water deficit was observed in these areas which hampered crop production. Area specific recommendations are thus required based on specific challenges in the study region.
Assessing the effects of intra-granule precipitation in a full-scale industrial anaerobic digester
Authors: Feldman H. , Flores-Alsina X. , Ramin P. , Kjellberg K. , Jeppsson U. , Batstone D. J. , Gernaey K. V. 
Published: April 2019

Abstract
In this paper, a multi-scale model is used to assess the multiple mineral precipitation potential in a full-scale anaerobic granular sludge system. Reactor behaviour is analysed under different operational conditions (addition/no addition of reject water from dewatering of lime-stabilized biomass) and periods of time (short/long term). Model predictions suggest that a higher contribution of reject water promotes the risk of intra-granule CaCO3 formation as a result of the increased quantity of calcium arriving with that stream combined with strong pH gradients within the biofilm. The distribution of these precipitates depends on: (i) reactor height; and (ii) granule size. The study also exposes the potential undesirable effects of the long-term addition of reject water (a decrease in energy recovery of 20% over a 100-day period), caused by loss in biomass activity (due to microbial displacement), and the reduced buffer capacity. This demonstrates how both short-term and long-term operational conditions may affect the formation of precipitates within anaerobic granules, and how it may influence methane production and consequently energy recovery.
Zona oeste da cidade do rio de janeiro: Entre o rural e o urbano
Authors: Silva Alves de Oliveira Maria Amália 
Published: April 2019

A Zona Oeste da Cidade do Rio de Janeiro (Brasil) se constituiu entre o rural e o urbano. Seu processo de integração econômico, social, político, cultural e ambiental foi construído em torno da ideia de natureza e da vocação agrícola, ainda não completamente apagada da memória social. Diante do presente e do passado da Zona Oeste, observa-se a tensão entre duas identidades construídas a partir de referenciais relacionados ao urbano e ao rural. Desta forma, a proposta do presente trabalho incide sobre análise do processo histórico que fornece as bases memoriais onde se assentam as representações coletivas acerca das categorias rural e urbano constituinte da identidade dos moradores da referida região. A pesquisa que subsidia aqui exposta resulta do projeto “Visite seu bairro” que está sendo desenvolvido desde 2010 e do projeto “Zona Oeste Revisitada: memória, patrimônio e turismo”, este último financiado através de recursos públicos oriundos do Edital FAPERJ Nº 42/2014.Palavras-chave: Zona Oeste. Rural. Urbano. Representações Coletivas. Memória Coletiva.West zone of the city of rio de janeiro: Between rural and urbanAbstractThe ZonaOeste of the City of Rio de Janeiro (Brazil) was constituted between the rural and the urban. Its process of economic, social, political, cultural and environmental integration was built around the idea of nature and the agricultural vocation, not yet completely erased from social memory. In view of the present and the past of the ZonaOeste, one can observe the tension between two identities built from references related to urban and rural. In this way, the proposal of the present work focuses on analysis of the historical process that provides the memorandum bases where the collective representations are based on the rural and urban categories constituting the identity of the inhabitants of that region. The research that subsidizes here is a result of the project "Visit your neighborhood" that has been developed since 2010 and the project "ZonaOeste Revisited: memory, heritage and tourism", the latter financed through public funds from FAPERJ Edict No. 42/2014 .Keywords: ZonaOeste. Rural. Urban. Collective Representations. Collective Memory.