bluuebunny/crossref_metadata_2025_split huggingface dataset:
Troposphere–Stratosphere Coupling Following Tropospheric Blocking and Extratropical Cyclones
Authors: Attard Hannah E. , Lang Andrea L. 
Published: March 2019

Abstract
A climatology of the 100- and 250-hPa 45°–75°N zonal-mean meridional eddy heat flux anomaly, hereafter heat flux anomaly, was created to examine its variability following cool-season (i.e., October–April) blocks and extratropical cyclones. The goal is to elucidate the dynamical and environmental differences between synoptic events followed by the most extreme heat flux anomalies. The analysis was conducted with the National Aeronautics and Space Administration’s Modern-Era Retrospective Analysis for Research and Applications, version 2 reanalysis. The results show that, on average, European blocks and west Pacific cyclones are followed by positive heat flux anomalies while west Pacific blocks and Atlantic extratropical cyclones are followed by negative heat flux anomalies. However, there was a large range of the 11-day-average heat flux anomaly following the events. Events in each region were further partitioned by their 100-hPa heat flux anomaly for a temporal and spatial analysis of the top and bottom quartile of events. Top-quartile events exhibited a baroclinic wave structure with height from the troposphere through the stratosphere, whereas bottom-quartile events were associated with a barotropic wave structure with height; these structures are significant at the 5% level. The results suggest that the sign of the heat flux anomaly is not dependent on the location of the synoptic event alone, but that there are common climatological and anomalous wave patterns surrounding the synoptic events that result in positive or negative heat flux anomaly. Regardless of event region, the precursor stratospheric structure is a key indicator in whether an event is followed by positive or negative 100-hPa heat flux anomalies.
A Radiographic Sizing Algorithm for Tibial Plateau Osteochondral Allografts
Authors: Trofa David P. , Graham William C. , McCullough Kirk A. , Lattermann Christian , Flanigan David C. , Corpus Keith T. , Saltzman Bryan M. , Fleischli James E. , Piasecki Dana P. 
Published: March 2019

Objective Tibial plateau osteochondral allograft transplantation is a promising treatment for symptomatic chondral damage of the proximal tibia due to a variety of etiologies. The purpose of this investigation is to develop an accurate and reproducible algorithm for sizing tibial plateau allografts based on recipient radiographs. Design A cadaveric study was performed in which radiographs of 10 fresh frozen cadaveric knees were compared to measured digital photographs of the disarticulated specimens. By comparing the average distance between standard anatomical landmarks on the radiographs to the gross specimens, a correlation factor was calculated that could be applied to recipient radiograph measurements for more accurate sizing of tibial plateau allografts. Results In the coronal plane there were no differences between the mean radiographic and mean morphologic measurements of either the medial or lateral tibial plateau. However, in the sagittal plane the anatomic specimens of the medial and lateral plateau were 90% and 80%, respectively, of the measurements made from the lateral radiograph. Conclusions This cadaveric investigation is the first to propose a sizing algorithm for tibial plateau osteochondral allografts. Based on the results, an anteroposterior radiograph can reliably measure the width of both the medial and lateral tibial plateau without any correction needed. The average morphological lengths of the medial and lateral tibial plateau, on the other hand, were found to be 90% and 80%, respectively, of the radiographically measured lengths. Without correction, this would lead to the implantation of oversized grafts that may contribute to early failure.
Age differences in contemporary treatment of patients with chronic heart failure and reduced ejection fraction
Authors: Veenis Jesse F , Brunner-La Rocca Hans-Peter , Linssen Gerard CM , Geerlings Peter R , Van Gent Marco WF , Aksoy Ismail , Oosterom Liane , Moons Arno HM , Hoes Arno W , Brugts Jasper J ,   for the CHECK-HF investigators
Published: March 2019

AbstractBackgroundElderly patients are underrepresented in clinical trials but comprise the majority of heart failure patients. Data on age-specific use of heart failure therapy are limited. The European Society of Cardiology heart failure guidelines provide no age-specific treatment recommendations. We investigated practice-based heart failure management in a large registry at heart failure outpatient clinics.Design and methodsWe studied 8351 heart failure with reduced ejection fraction patients at 34 Dutch outpatient clinics between 2013 and 2016. The mean age was 72.3 ± 11.8 years and we divided age into three categories: less than 60 years (13.9%); 60–74 years (36.0%); and 75 years and over (50.2%).ResultsElderly heart failure with reduced ejection fraction patients (≥75 years) received significantly fewer beta-blockers (77.8% vs. 84.2%), renin–angiotensin system inhibitors (75.2% vs. 89.7%), mineralocorticoid receptor antagonists (50.6% vs. 59.6%) and ivabradine (2.9% vs. 9.3%), but significantly more diuretics (88.1% vs. 72.6%) compared to patients aged less than 60 years (Pfor all trends &lt; 0.01). Moreover, the prescribed target dosages were significantly lower in elderly patients. Also, implantable cardioverter defibrillator (18.9% vs. 44.1%) and cardiac resynchronisation therapy device (14.6% vs. 16.7%) implantation rates were significantly lower in elderly patients. A similar trend in drug prescription was observed in patients with heart failure with mid-range ejection fraction as in heart failure with reduced ejection fraction.ConclusionWith increasing age, heart failure with reduced ejection fraction patients less often received guideline-recommended medication prescriptions and also in a lower dosage. In addition, a lower percentage of implantable cardioverter defibrillator and cardiac resynchronisation therapy device implantation in elderly patients was observed.
Evaluating the feasibility of using candidate DNA barcodes in discriminating species of the large Asteraceae family
Authors: Gao Ting , Yao Hui , Song Jingyuan , Zhu Yingjie , Liu Chang , Chen Shilin 
Published: March 2019

Abstract

Background
Five DNA regions, namely, rbcL, matK, ITS, ITS2, and psbA-trnH, have been recommended as primary DNA barcodes for plants. Studies evaluating these regions for species identification in the large plant taxon, which includes a large number of closely related species, have rarely been reported.

Results
The feasibility of using the five proposed DNA regions was tested for discriminating plant species within Asteraceae, the largest family of flowering plants. Among these markers, ITS2 was the most useful in terms of universality, sequence variation, and identification capability in the Asteraceae family. The species discriminating power of ITS2 was also explored in a large pool of 3,490 Asteraceae sequences that represent 2,315 species belonging to 494 different genera. The result shows that ITS2 correctly identified 76.4% and 97.4% of plant samples at the species and genus levels, respectively. In addition, ITS2 displayed a variable ability to discriminate related species within different genera.

Conclusions
ITS2 is the best DNA barcode for the Asteraceae family. This approach significantly broadens the application of DNA barcoding to resolve classification problems in the family Asteraceae at the genera and species levels.
PTH Modulation by Aldosterone and Angiotensin II is Blunted in Hyperaldosteronism and Rescued by Adrenalectomy
Authors: Lenzini Livia , Prisco Selene , Vanderriele Paul Emmanuel , Lerco Silvia , Torresan Francesca , Maiolino Giuseppe , Seccia Teresa Maria , Iacobone Maurizio , Rossi Gian Paolo 
Published: March 2019

Abstract

Context
Accumulating evidence suggests a link between adrenocortical zona glomerulosa and parathyroid gland through mechanisms that remain unexplored.

Objectives
To test the hypothesis that in vivo angiotensin II blockade affects PTH secretion in patients with hypertension and that aldosterone and angiotensim II directly stimulate PTH secretion ex vivo.

Design and Setting
We investigated the changes of serum PTH levels induced by oral captopril (50 mg) administration in patients with primary essential hypertension (EH) and with primary aldosteronism (PA) caused by bilateral adrenal hyperplasia (BAH) or aldosterone-producing adenoma (APA), the latter before and after adrenalectomy. We also exposed primary cultures of human parathyroid cells from patients with primary hyperparathyroidism to angiotensin II (10−7 M) and/or aldosterone (10−7 M).

Results
Captopril lowered PTH levels (in nanograms per liter) both in patients with EH (n = 63; 25.9 ± 8.3 baseline vs 24.4 ± 8.0 postcaptopril, P < 0.0001) and in patients with APA after adrenalectomy (n = 27; 26.3 ± 11.6 vs 24.0 ± 9.7 P = 0.021). However, it was ineffective in patients with full-blown PA caused by APA and BAH. In primary culture of human parathyroid cells, both aldosterone (P < 0.001) and angiotensin II (P = 0.002) markedly increased PTH secretion from baseline, by acting through mineralocorticoid receptor and angiotensin type 1 receptor, as these effects were abolished by canrenone and irbesartan, respectively.

Conclusion
These results collectively suggest an implication of the renin-angiotensin-aldosterone system in PTH regulation in humans, at least in PTH-secreting cells obtained from parathyroid tumors. Moreover, they further support the concept that mild hyperparathyroidism is a feature of human PA that is correctable with adrenalectomy.
Apreendendo a inclusão social sob o olhar das representações sociais
Authors: Paulino Ana Cristina de Oliveira Borba , Coutinho Maria Da Penha de Lima , Costa Fabrycianne Gonçalves 
Published: March 2019

Este estudo objetivou apreender as representações sociais (RS) acerca da inclusão social, elaboradas por pessoas com deficiência visual. Participaram deste estudo 30 pessoas com idade entre 18 e 69 anos, M = 34,2 e DP = 14,4, contatadas em duas instituições públicas, que responderam a um questionário psicossociológico e à entrevista em profundidade. Os dados foram processados pelo SPSS 19.0 e pelo Alceste, e analisados por meio da estatística descritiva e análise lexical. Os resultados apontaram que as RS da inclusão social das pessoas com deficiência visual foram objetivadas por meio das expressões: ambiente físico escolar inadequado, dificuldade na acessibilidade urbana, equipe educacional despreparada para lidar com a diversidade, distância entre as leis e sua aplicabilidade e desconhecimento dos direitos sociais. Ancorado na dialética inclusão/exclusão evidenciada nos aspectos multifacetados desse processo, pelos enunciados percebeu-se que os participantes têm consciência da importância da educação no processo de inclusão à sociedade, uma vez que esta propicia o acesso ao mercado de trabalho, ao lazer e à conquista da cidadania. Espera-se que os resultados possam contribuir para uma melhor conscientização por parte da sociedade no que tange à inclusão/exclusão social no contexto da deficiência visual.
"Seminários Livres: Qlínica, com quê?": contribuições de Marcus Vinícius de Oliveira Silva à psicologia brasileira
Authors: Tchalekian Bruna Borba de Araújo , Pereira Yasmin De Sousa 
Published: March 2019

O presente artigo tem como objetivo apresentar um estudo inicial sobre o projeto "Seminários Livres: Qlínica, com quê?", construído pelo psicólogo e professor Marcus Vinícius de Oliveira Silva e promovido pelo Laboratório de Estudos Vinculares e Saúde Mental - IPS/UFBA. Os seminários constituíram-se como espaços de formação para alunos e profissionais, visando o fortalecimento do trabalho clínico desenvolvido no âmbito da Rede Psicossocial de Saúde Mental. Serão apresentadas discussões referentes ao trabalho da clínica ampliada e ao desenvolvimento de diagnósticos diferenciais no contexto da saúde pública. Conclui-se que o projeto constituiu-se como espaço potente para fortalecimento e reflexão acerca dos desafios do trabalho da rede e sua difusão configura-se como possibilidade de ampliação dos saberes ali desenvolvidos.
Point-of-care blood tests in decision-making for people over 65 with acute frailty
Authors: McPherson Melinda (Dolly) 
Published: March 2019

Background: National ‘see, treat and discharge’ rates for paramedics have increased. However, despite the rise in demand on paramedic decision-making, there have been few improvements to prehospital diagnostics. Patients aged over 65 years presenting with acute frailty syndromes are a notably complex clinical patient group for whom informed risk stratification in clinical reasoning is paramount. Methods: This was a single-site quality improvement project using point-of-care blood testing (POCbT) to help inform decision-making for patients aged above 65 years with acute frailty syndromes. Results: This quality improvement project showed a self-reported improved confidence in clinician decision-making and patient disposition with the use of POCbT. This confidence was validated by improved discharge on scene and recontact rates. An unintended outcome of the project was the accumulation of practical knowledge on the use of POCbT in the prehospital arena. Conclusion: Continued use of POCbT in the prehospital environment has promise but this is not without limitations. Prehospital services wishing to implement POCbT should focus on demographic identification, staff training and interpretation of results.
Home visits from paramedic practitioners in general practice: patient perceptions
Authors: Proctor Alyesha 
Published: March 2019

Background: As set out in the General Practice Forward View (NHS England, 2016), the success of general practice will rely on new ways of working, including having a multidisciplinary workforce. The role of the paramedic practitioner (PP) working within a GP surgery was proposed in a report by the Primary Care Workforce Commission ( Health Education England, 2015 ). The role involves PPs having their own clinics within the GP surgery, managing a variety of presenting complaints, as well as conducting urgent home visits to assist with GP workload. However, what are patients' perceptions of being attended to by the PP in place of the GP? Aim: To explore older patients' perceptions of having PPs, who work in GP surgeries, attend to them on a home visit in place of the GP. Method: A qualitative study using face-to-face, semi-structured interviews, with thematic analysis. Findings: There is confusion regarding the role of the PP, with a strong desire to be informed more about it. However, despite this confusion, there is a positive perception among older patients of having a PP attend to them on a home visit in place of the GP. The patients felt that the PP managed their complaints well, and was equipped with the required skills and knowledge. Conclusion: Information needs to be provided to the public to increase awareness of the PP role. The role of the paramedic is changing; however, there is little published research investigating the contribution of paramedics working in primary care. This pilot study serves to highlight areas that require further investigation on the influence of the PP in general practice.
Pendekatan Regresi Data Panel untuk Pemodelan Jumlah Angkatan Kerja dan Penanaman Modal Luar Negeri terhadap PDRB Provinsi di Indonesia
Authors: Syukron Muhammad , Fahri Hafidz Muhammad 
Published: March 2019

<p>Indonesia is a country with great economic potency. Indonesia has a vast area and abundant natural products, but until now Indonesia is still a developing country. The Indonesian economy is defeated by other countries such as Japan, China and South Korea even by the neighboring country, Singapore. Increasing the national economy can be started from improving the regional economy which can be measured by gross regional domestic product (GRDP). Indonesia will experience a demographic bonus in 2045 so that the population of productive age is expected to contribute a lot to economic growth. The large number of productive age population must be balanced with the availability of jobs so that this momentum can be fully utilized. Foreign investment can be a solution when domestic capital is insufficient in financing economic activities. In addressing this phenomenon, a statistical analysis of panel data regression was conducted to see the relationship between independent variables, namely the number of labor force and realization of foreign investment, and a dependent variable, namely GRDP at constant prices in 2010 for every province in Indonesia. We use time series data in 2015-2017 and cross-sectional data of 34 provinces in Indonesia taken from BPS official website. The estimation result shows that both independent variables partially and fully have a significant effect on the GRDP with an adjusted <em>R<sup>2</sup></em> of 99.86%.</p><p> </p><p><strong>Keywords</strong><strong>: </strong>Labor force; regression; panel data; foreign capital; GRDP.</p>
Uncanny arts and the aesthetics of cyberneticexistentialism
Authors: Dixon Steve 
Published: March 2019

Abstract
‘Uncanny’ works by a number of contemporary artists are analysed in relation to the themes and insights of both cybernetics and existentialist philosophy. This reveals that central ideas from these largely neglected fields remain current and potent within innovative art practices. Artists employ cybernetic systems to provoke aesthetic sensations of the uncanny, while simultaneously encapsulating existentialist concerns. Pierre Huyghe’s mysterious installation responds to the life-breath of visitors to mutate human cancer cells. Susan Collins and Rafael Lozano-Hemmer construct cybernetic worlds-within-worlds to render us beings-for-others during intimate encounters with strangers. Urich Lau and TC&A involve and implicate the audience in eerie expressions of what existentialist term being-towards-death. These artworks prompt feelings of separation, alienation and existential angst; and emphasize human estrangement within a mysterious, incomprehensible or absurd world. But a cybernetic-existentialist reading also reveals that their evocation of human disquiet and isolation is tempered by an equal emphasis on positive notions of feedback loops, ‘separation with communion’, existential freedom and authentic interactions with the world and with Others. The artworks articulate cybernetics’ and existentialism’s shared interest in collapsing boundaries and erasing distinctions: between agents within a system; between the self and the Other; and between perceiving, feeling and acting.
Convergence analysis of an inertial accelerated iterative algorithm for solving split variational inequality problem
Authors: Ogbuisi Ferdinard U. , Mewomo Oluwatosin T. 
Published: March 2019

AbstractIn this paper, we introduce an iterative scheme involving an inertial term and a step size independent of the operator norm for approximating a solution to a split variational inequality problem in a real Hilbert space.
Furthermore, we prove a convergence theorem for the sequence generated by the proposed operator norm independent inertial accelerated iterative scheme.
We applied our result to solve split convex minimization problems, split zero problem and further give a numerical example to demonstrate the efficiency of the proposed algorithm.
Necessity of Reinterpretation of Sharia in the Thoughts of a Grand Ayatollah: Saanei’s Response to the Challenge of Human Rights in Islam
Authors: Goudarzi Masoumeh Rad , Najafinejad Alireza 
Published: March 2019

Abstract
The common method of the traditional Islamic Jurisprudence in seminaries has been challenged by Ayatollah Yousef Saanei, one of the ten prominent Iranian Grand Ayatollahs. Saanei is well known for attempting to institutionalize a new method of Ijtihad, known as searching Ijtihad, which seeks to reconsider the common mode of understanding religious texts and jurisprudential inferences. His experiences of observing the systematic ineffectiveness and discrimination in popular jurisprudence regarding women’s rights, family, and religious minorities persuaded him to take scientific action in revising the common jurisprudential method. In the present paper, the necessity of revising the common jurisprudential approach in seminaries from Saanei’s point of view is firstly studied. Afterwards, the foundations, principles, and methods of modern Saanei’s Ijtihad will be investigated to determine the structure and foundations of his jurisprudential method and evaluate its impact on resolving the contradictions between traditional perceptions of religion and human rights.
Ischemic Preconditioning Improves Strength Endurance Performance
Authors: Carvalho Leonardo , Barroso Renato 
Published: March 2019

Abstract
Carvalho, L and Barroso, R. Ischemic preconditioning improves strength endurance performance. J Strength Cond Res 33(12): 3332–3337, 2019—Ischemic preconditioning (IPC) has been used to improve performances in aerobic and anaerobic activities. However, a few studies aimed at observing the effects of IPC on resistance training. The purpose of this study is to examine the effects of IPC on the number of repetitions performed during high-load resistance training. We also aimed at investigating blood lactate concentration and muscle activation in an attempt to understand the physiological mechanisms that may be caused by IPC. Ten resistance-trained participants performed four 5-minute cycles of either IPC (250 mm Hg) or Placebo (10 mm Hg) before performing a single set to failure of knee extension exercise with 85% of 1 repetition maximum. We also assessed muscle activation during the set (EMGRMS), median power frequency (EMGMPF), and blood lactate concentration before, 3, 7, and 11 minutes after (peak value was identified and used to calculate delta to prevalues, Δlactate). Data are presented as mean, 90% confidence intervals (CIs), and were analyzed with paired t-test. The level of significance was set at p < 0.05. Participants performed on average 3.9 repetitions (90% CI = 2.4–5.4; p = 0.01), which is ∼20%, more in the IPC condition. There were no significant differences between IPC and Placebo for EMGMPF (5.0%; 90% CI = −5.2 to 15; p = 0.50), EMGRMS (4.5%; 90% CI = −8.8 to 17; p = 0.78), and Δlactate (44%; 90% CI = 11–144; p = 0.16). Our results demonstrate the effect of IPC just on the number of repetitions performed in high-load resistance exercise compared with the Placebo condition.