bluuebunny/crossref_metadata_2025_split huggingface dataset:
Options for future European reusable booster stages: evaluation and comparison of VTHL and VTVL return methods
Authors: Stappert Sven , Dietlein Ingrid , Wilken Jascha , Bussler Leonid , Sippel Martin 
Published: November 2024

Abstract
In the past, the majority of system studies on reusable space transportation performed within Europe focused on concepts relying on lift-generating wings for recovery. Recently, vertically landing concepts similar to those deployed successfully by SpaceX have moved to the center of technical attention. Both recovery and landing strategies have their pros and cons and it is not obvious what would be a sound choice for Europe. Therefore, the German Aerospace Center DLR initiated a parametric system study, named ENTRAIN, that evaluates the impact of different return options on the launcher design on a technical level: the vertical take-off, vertical landing method (VTVL) as used by SpaceX compared to the vertical take-off, horizontal landing (VTHL) method as used for the Space Shuttle. Within this study, launchers were designed using different propellant combinations, staging velocities and engine cycles. The designed launchers are evaluated in this paper regarding performance, technical difficulties, operational aspects, size, mass and complexity.
Mechanism of CXCL8 regulation of methionine metabolism to promote angiogenesis in gliomas
Authors: Chang Jie , Pan Yi , Jiang Fengfeng , Xu Wenxia , Wang Yue , Wang Lude , Hu Bin 
Published: November 2024

Abstract
Background
Gliomas are the most common malignant brain tumors characterized by angiogenesis and invasive growth. A detailed understanding of its molecular characteristics could provide potential therapeutic targets. In the present study, we sought to explore the key gene CXCL8 in methionine metabolism in gliomas and its potential role in angiogenesis.

Methods
U251 glioma cells were divided into control and methionine-restriction tolerant (constructed with 1/4 of the standard level of methionine in the culture medium) groups for transcriptome and metabolome analysis. To confirm the functions and mechanism of CXCL8 in glioma, heat map, volcano map, Go enrichment, gene set enrichment analysis (GSEA), protein–protein interaction network analysis, RT-PCR, western blotting assays, chicken embryo chorioallantoic membrane (CAM) test, chicken embryo yolk sac membrane (YSM) test and transplantation tumor nude mice model were performed. The TCGA database, CGGA database and clinical tissue samples were used to analyze CXCL8’s significance on prognosis for patients with glioma.

Results
CXCL8 expression was significantly up-regulated in methionine-restricted tolerance cells, it also activated vascular system development and triggered angiogenesis. CXCL8 expression is negatively correlated with survival prognosis in gliomas.

Conclusions
Glioma cells promote angiogenesis in methionine-restricted environments through the activation of CXCL8, compensating for nutrient deprivation, and possibly contributing to the failure of antiangiogenic therapy.
Interfacial and mass transport phenomena in the tri-ethylene glycol-methane system at process conditions of natural gas dehydration
Authors: Ibeh Stanley , Jaeger Philip 
Published: November 2024

AbstractUnderstanding the phase and interphase behavior at equilibrium and during the mass transfer between two adjacent fluid phases is relevant for optimizing and designing efficient separation processes. This study experimentally investigates the interfacial and transport behavior of systems comprising tri-ethylene glycol (TEG) and methane (CH4) under conditions relevant to the gas dehydration process. A comprehensive review of the interfacial tension (IFT) and diffusivity of systems involving non-polar and polar compounds at elevated pressures was studied. However, a research gap exists, particularly concerning the interfacial tension of systems involving TEG, TEG + water, and different types of gases as well as the diffusivity of CH4 in TEG. To address this gap, this study presents new data on mixture densities, interfacial tension, and drop volumes of TEG and TEG + water in CH4 and CH4 + CO2 mixtures at temperatures ranging from 20 to 50 °C and pressures up to 250 bar using the oscillating U-tube and pendant drop methods, respectively. Additionally, time-dependent fluid mixture densities and TEG droplet volumetric expansion, coupled with an analytical approach for the binary diffusion were applied to determine the CH4 solubility and diffusivity in TEG. The results show that IFT and drop volume of TEG and TEG + water in CH4 and CH4 + CO2 mixtures decrease with increasing pressure. The presence of water increases the IFT of TEG-CH4 up to $$\sim$$
∼
5mN/m, while CO2 reduces it by $$\sim$$
∼
2mN/m. Interestingly, the IFT and drop volume of TEG-CH4 show no significant change at elevated pressures when temperatures rise from 20 to 50 °C. IFT remains relatively constant over time at moderate pressures but decreases by $$\sim$$
∼
3mN/m at an elevated pressure of 150 bar, suggesting methane solubilization into TEG to have a significant influence which is confirmed by TEG drop volume expansion. The diffusivity of CH4 in TEG at 150 bar and 50 °C is determined to be in the range of 10–10 m2/s, which is in agreement with the diffusivity of CH4 in liquids of similar viscosity, i.e. according correlations may be applied as good engineering practice. To the best of our knowledge, there is no such comprehensive work on the properties of fluid mixtures relevant in gas dehydration processes published up to date.
A simplified automated approach for a preliminary safety assessment of distributed electric and hybrid propulsion systems
Authors: Albrecht Alexander , Siegel Joachim , Strohmayer Andreas 
Published: November 2024

AbstractTo reduce the environmental impact of future aircraft, the usage of disruptive hybrid electric propulsion systems, in conjunction with distributed propulsion systems, is envisioned. The complexity of those novel powertrain concepts increases significantly. Besides nominal system characteristics, this particularly applies for off-nominal behaviour and consequences. As the safety impact on aircraft level is not always obvious, the suitability of a given component failure rate has to be analysed already in a preliminary design stage. Within this work, a method shall be introduced that allows a simplified automated safety assessment of any powertrain architecture. All relevant combinations of single and multiple failures are identified and a combined failure rate is derived. Thereafter, the impact of single and multiple component failures is evaluated on aircraft level. A selection of metrics for top-level-aircraft functions is used to implement an impact-driven analysis for each relevant failure case. The metrics used assess the adverse effects on climb performance, lateral controllability and range degradation. For all failure combinations, these effects can be validated against requirements imposed on the configuration. The possibility to formulate failure rate-related requirements follows the idea to target an equivalent level of safety compared to existing regulations, independently of the nature of the failure scenario. Results of this study show the necessity for a reevaluation of the configurations assessed, either regarding their architecture or the assumed component failure rate. The method allows an early detection of configuration-specific shortcomings of complex powertrain architectures already in a preliminary aircraft design stage.
Optimizing mechanical properties and pioneering biodegradable polymer blends for superior energy-absorbing structures used in sport helmets
Authors: Skwarski Mateusz , Kaczyński Paweł , Dmitruk Anna , Makuła Piotr , Ludwiczak Joanna 
Published: November 2024

Abstract
Replacing elements made of conventional plastics (like polystyrene) with biodegradable substitutes is part of the trend of sustainable development and waste reduction. The manuscript covers issues related to the design, manufacturing and testing of sports helmet protective inserts made of biodegradable material. The FEM numerical simulations carried out by the authors allowed to determine the optimal desirable mechanical properties (R
e = 8.5–65 MPa, E = 500–8000 MPa for 30 × 30 mm inserts; R
e = 10.5–60 MPa, E = 500–7500 MPa for 48 × 48 mm inserts; R
e = 13–95 MPa, E = 400–8500 MPa for 55 × 55 mm inserts) and geometric parameters (wall thickness equal to 0.2–0.5 mm, height of 20 mm), ensuring the formation of a plastic fold, which is the most effective energy-absorbing mechanism. The conducted quasi-static compression, bending and dynamic tensile strength tests allowed to determine blends with appropriate proportions of durable PLA with more plastic PBAT, PBS and TPS that meet the established criteria: PLA50PBAT50, PLA30PBAT70 and PLA30TPS70.
Specification of INF01LE, INF03, and INF04LE infrasound sensors for the observation and detection of destructive geophysical events
Authors: Nishikawa Yasuhiro , Yamamoto Masa-Yuki , Yokota Akihiro , Hasumi Yuta , Hamajima Gaku 
Published: November 2024

Abstract
When an object moves through the atmosphere, it induces pressure fluctuations. If the scale of the object’s movement spans several hundred meters to several kilometers, the period of the pressure fluctuation will range from several seconds to several tens of seconds, determined by the ratio of the scale to the speed of sound. These pressure fluctuations manifest within the frequency range between audible sound (> 20 Hz) and infrasound (< 20 Hz and > 3 mHz). The infrasonic waves, characterized by their low-frequency nature, present a promising avenue for long-distance remote sensing, particularly in the monitoring of geophysical events with the potential for widespread destruction, such as earthquakes and tsunamis. We developed sensors of both membrane and microphone types to monitor infrasound in lower or higher frequency, respectively. These sensors were installed on the Pacific side of Japan to observe infrasound mainly generated by tsunamis. The key advantage lies in the faster propagation speed of Lamb waves (

$$\sim$$

∼

310 m/s) compared to that of tsunami waves (

$$\sim$$

∼

200 m/s), making them a valuable precursor for timely detection. By combining with a small MEMS 3-axis accelerometers, this study explores the feasibility of identifying a sudden atmospheric pressure surge within the infrasonic frequency range, following a significant earthquake. The observed surge serves as a crucial indicator of the imminent arrival of large tsunami waves along the shoreline situated between the earthquake’s epicenter and the observation site. The practical implication of this detection methodology is profound, as it could potentially trigger early warning systems, leading to timely and targeted evacuations. These infrasound sensors effectively detected infrasound produced not only by tsunamis but also by volcanic eruptions, meteorite explosions, and so on. This research focuses on the significance of monitoring geophysical events in the infrasound frequency range by demonstrating the development of our infrasound sensors and the natural phenomena captured by these instruments. The study presents observational results based on three types of sensors (INF01LE, INF03, and INF04LE), each exhibiting a flat response within specific frequency ranges: 0.003 to 6.25 Hz, 0.1 to 100 Hz, and 0.1 to 100 Hz, respectively. These sensors have been rigorously tested across various natural phenomena to validate their effectiveness in capturing infrasonic waves. The findings of this research contribute to the growing body of knowledge on infrasonic wave coming from various geophysical disaster perspectives.
Investigations into the foaming behavior of ABS by means of granule extrusion using expandable microspheres
Authors: Wille Toni , Pensel Hans Georg , Barz Andrea , Hopf Andreas , Bliedtner Jens , Danz Karl-Christian 
Published: November 2024

AbstractThe following investigations address the production of syntactic polymer foams using thermally expanding microspheres (TEM) in the extrusion process. A process model for the foaming behavior of acrylnitrile butadiene styrene (ABS) with thermally expanding microspheres as masterbatch is derived by varying the two basic process parameters extruder rotational speed and extruder temperature in a test matrix with five stages each. The investigations include the production of unfoamed and foamed strands and the measurement of process relevant properties and parameters such as extrusion mass flow, relative density of the structures, die-swelling and the characterization of the generated foam structures. The achievable density reduction is within the order of 50%. The process model resulting from the investigations allows the production of homogeneously foamed strands. These results are intended to serve as the basis for a transfer to the Large Scale Additive Manufacturing (LSAM) process.
The Effect of Disaster Preparedness Literacy on Individual Disaster Resilience
Authors: Torpus Kemal , Usta Galip , Çinar Özbay Sevil , Kanbay Yalçın 
Published: November 2024

Abstract
This study aimed to examine the effect of disaster preparedness literacy on individual disaster resilience and related factors. The universe of the research consists of individuals between the ages of 18-52. Software packages AMOS 23 and SPSS 26 were used to analyze the study’s data. Mann Whitney U test and Kruskal Wallis H test were used for non-parametric variables, whereas the T test and ANOVA were used for parametric variables. The associations between variables were investigated using correlation analysis and basic linear regression analysis. According to the findings, as disaster literacy increases, individual disaster resilience increases. The individual disaster resilience level of males was higher than that of females, the individual disaster resilience level of married individuals was higher than that of single individuals, and those who have experienced a disaster before have a higher level of individual disaster resilience than those who haven’t experienced a disaster. Males have higher levels of disaster literacy than females. Married individuals have higher disaster literacy levels than singles. As the age increases, the level of individual disaster resilience and disaster literacy increases. It is considered important to develop community-based disaster awareness training programs and strategies to increase individual disaster resilience.
Midwifery Experiences During Two Major Earthquakes in Türkiye: Challenges and Lessons Learned - A Qualitative Study
Authors: Çağlayan Keleş Neriman 
Published: November 2024

Abstract

Objectives
This study aims to identify midwives’ post-earthquake caregiving experiences.

Methods
A phenomenological study was undertaken in May-June 2023. The participants of the study consisted of 15midwives who were included in the study with the purposeful sampling method and volunteered to provide care during the earthquake. Data were collected by an in-depth interview method using a demographic information form and a semi-structured interview form. Thematic analysis was conducted on interview transcripts.

Results
The research identified 2main themes: difficulties in managing midwifery care and the psychological impact of the earthquake on midwives. Challenges included issues with disaster organization, management, and coordination; communication gaps; insufficient medical supplies; harsh environmental conditions; inability to fulfill basic needs; lack of disaster-related knowledge and experience among midwives; and the overall survival conditions of disaster victims. The disaster caused several psychological effects on midwives, including shock, surprise, sadness, confusion, feelings of inadequacy, insomnia upon returning from the disaster area, nightmares, difficulty adapting, guilt about returning, feelings of helplessness, and experiences of loss and mourning.

Conclusions
This study detailed midwives’ experiences during disasters, difficulties, and barriers to effective care. It is crucial to record midwives’ experiences during disasters and use this information and solutions to prepare for future disasters. Disaster preparedness training for midwives should be planned to increase physical and emotional resilience.
Fringe Consumers
Authors: Mars Matthew M. , Schau Hope J. 
Published: November 2024

Abstract
We all consume the humanities through our engagement with the cultural, creative, and historical materials that influence our views on ourselves, others, and the world around us. However, can consumers also be considered humanists? We argue the answer is yes when consumption choices become symbols and expressions of one’s authentic self and meaningful connective points to others. Using hard-core surfing enthusiasts and thrifters as examples, we introduce the notion of fringe consumption as a form of cultural entrepreneurship and public expression of the humanities that centers individuality, authenticity, and otherness in an otherwise dominant mainstream environment that pushes people to always want more of the same.
Above the Law: From Medieval England to Trump v. the United States
Authors: Herman Peter C. 
Published: November 2024

Abstract
There is nothing unprecedented about prosecuting Donald Trump. While it’s certainly true that no president has (yet) to be indicted, if we look at to the long stretch of English political-legal history, we find many precedents. Because what happened in England fueled the American Revolution and the Framers’ view of the chief executive. As Richard II and Charles I discovered to their cost, acting as if they were above the law could lead to their deposition and eventual death, and the framers agreed. Thomas Jefferson asserted in A Summary View of the Rights of British America (1774), retained “the powers of punishment or removal” of their rulers. Holding the chief executive, whether a king, a prime minister, or a president is irrelevant, to account for alleged crimes is, as the phrase goes, baked into American constitutional law. But the Supreme Court has ruled otherwise. The president now enjoys the immunity Charles I claimed. We are now at the cusp of something without precedent: an absolutist presidency.
The relationship between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and metabolic health status in adolescents with overweight and obesity: results from a cross-sectional study in Iran
Authors: Khakbaz Maryam , Poursalehi Donya , Mirzaei Saeideh , Asadi Ali , Akhlaghi Masoumeh , Saneei Parvane 
Published: November 2024

AbstractFew studies investigated the association between Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and metabolic health status, particularly among adolescents. The present study was designed to investigate the association of MIND diet with metabolic health status in Iranian adolescents with overweight/obesity. This cross-sectional study was done among 203 adolescents with overweight/obesity (12–18 years) in Isfahan, Iran. A validated FFQ was applied to collect dietary intakes. Anthropometric indices and blood pressure were also measured by standard procedures. Fasting blood samples were obtained to determine serum insulin, glucose and lipid profile. To categorise participants as being with metabolically healthy overweight/obesity (MHO) or metabolically unhealthy overweight/obesity (MUO), two methods including International Diabetes Federation (IDF) criteria and IDF plus Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) were applied. Participants had a mean age of 13·98 years and 50·2 % of them were girls. In fully adjusted models, participants with highest MIND diet adherence had lower odds of MUO status based on IDF (OR = 0·20; 95 % CI 0·08, 0·51) and IDF/HOMA-IR (OR = 0·22; 95 % CI 0·08, 0·59) criteria. Stratified analyses revealed that this association was stronger among girls and was only significant among individuals with overweight. An inverse association was also found between MIND diet score and odds of hyperglycaemia and insulin resistance (IR). Higher MIND diet adherence was associated with lower odds MUO in adolescents with overweight/obesity. Inverse associations were also found between MIND diet and odds of hyperglycaemia and IR. Future longitudinal prospective studies are necessary to confirm our results.
Amino acid transport dynamics in the jejunum and ileum in rats: a regional and time-course analysis
Authors: Katsura Kojiro , Hira Tohru 
Published: November 2024

AbstractPostprandially, amino acids and di/tripeptides are thought to be primarily absorbed in the proximal small intestine. However, there have been no in vivo demonstrations of regional differences in amino acid transport dynamics between the proximal and distal small intestines. We monitored plasma amino acid responses in the jejunal and ileal mesenteric veins of rats after oral administration of a diet or an amino acid mixture (Expt 1) and in the portal vein after direct administration of the amino acid mixture into the lumen of the jejunum or ileum (Expt 2). In Expt 1, the total and some amino acid concentrations in the jejunal mesenteric vein were slightly higher than those in the ileal mesenteric vein after oral administration of the amino acid mixture, suggesting that the ileum actively transports luminal amino acids to the basolateral side, comparable to the jejunum. In Expt 2, portal amino acid concentrations were elevated to a greater extent after direct administration of the amino acid mixture into the ileal lumen than into the jejunal lumen. These results demonstrate regional differences in amino acid transport dynamics in vivo and suggest that the ileum has a higher capacity for transporting amino acids than the jejunum. Our findings highlight the importance of the ileum in postprandial amino acid absorption and metabolism.
Trends in dietary choline and betaine intake among Chinese adults: the China Health and Nutrition Survey 1991–2011
Authors: Chen Peiyan , Wu Shangling , Tan Peishan , Sui Yi , Lu Jialin , Peng Tianyou , Wang Wenting , Lu Wei , Zhu Huilian , Li Keji , Fang Aiping 
Published: November 2024

AbstractCholine and betaine are important in the body, from cell membrane components to methyl donors. We aimed to investigate trends in dietary intake and food sources of total choline, individual choline forms and betaine in Chinese adults using data from the China Health and Nutrition Survey (CHNS) 1991–2011, a prospective cohort with a multistage, random cluster design. Dietary intake was estimated using three consecutive 24-h dietary recalls in combination with a household food inventory. Linear mixed-effect models were constructed using R software. A total of 11 188 men and 12 279 women aged 18 years or older were included. Between 1991 and 2011, total choline intake increased from 219·3 (95 % CI 215·1, 223·4) mg/d to 269·0 (95 % CI 265·6, 272·5) mg/d in men and from 195·6 (95 % CI 191·8, 199·4) mg/d to 240·4 (95 % CI 237·4, 243·5) mg/d in women (both P-trends < 0·001). Phosphatidylcholine was the major form of dietary choline, and its contribution to total choline increased from 46·9 % in 1991 to 58·8 % in 2011. Cereals were the primary food source of total choline before 2000, while eggs had ranked at the top since 2004. Dietary betaine intake was relatively steady over time with a range of 134·0–151·5 mg/d in men (P-trend < 0·001) and 111·7–125·3 mg/d in women (P-trend > 0·05). Chinese adults experienced a significant increase in dietary intake of choline, particularly phosphatidylcholine during 1991–2011 and animal-derived foods have replaced plant-based foods as the main food sources of choline. Betaine intake remained relatively stable over time. Future efforts should address the health effects of these changes.