bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parent-adolescent sexual dialogue
Authors: Somers Cheryl , Avendt Emily , Sepsey Amber 
Published: June 2019

PurposeThe purpose of this paper is to explore how the content and approach of parent-adolescent communication about sexuality were associated with three adolescent sexuality variables (sexual attitudes, combination of all behaviors and advanced behaviors).Design/methodology/approachSurvey research with adolescents was conducted in classrooms at school. Participants were 473 adolescents (196 males, 253 females and 24 unreported) in grades 9–12 from two high schools (one urban and one suburban) in a large midwestern city.FindingsAdolescents who described their parents’ communication approach as open, or who did not engage in conversations about sexuality with their parents reported lower rates of sexual behavior, when compared to adolescents whose parents dictated such conversations. Females were found to have more conservative sexual attitudes than males, and both mothers and fathers were found to have a direct role in talking to their children about sexuality.Originality/valueFindings from the study may offer guidance to parents and help adults aiming to empower youth to make healthy sexual decisions.
Self-adaptive scale pedestrian detection algorithm based on deep residual network
Authors: Liu Shuang-Shuang 
Published: June 2019

Purpose
The conventional pedestrian detection algorithms lack in scale sensitivity. The purpose of this paper is to propose a novel algorithm of self-adaptive scale pedestrian detection, based on deep residual network (DRN), to address such lacks.

Design/methodology/approach
First, the “Edge boxes” algorithm is introduced to extract region of interests from pedestrian images. Then, the extracted bounding boxes are incorporated to different DRNs, one is a large-scale DRN and the other one is the small-scale DRN. The height of the bounding boxes is used to classify the results of pedestrians and to regress the bounding boxes to the entity of the pedestrian. At last, a weighted self-adaptive scale function, which combines the large-scale results and small-scale results, is designed for the final pedestrian detection.

Findings
To validate the effectiveness and feasibility of the proposed algorithm, some comparison experiments have been done on the common pedestrian detection data sets: Caltech, INRIA, ETH and KITTI. Experimental results show that the proposed algorithm is adapted for the various scales of the pedestrians. For the hard detected small-scale pedestrians, the proposed algorithm has improved the accuracy and robustness of detections.

Originality/value
By applying different models to deal with different scales of pedestrians, the proposed algorithm with the weighted calculation function has improved the accuracy and robustness for different scales of pedestrians.
Brand love matters to Millennials: the relevance of mystery, sensuality and intimacy to neo-luxury brands
Authors: Rodrigues Clarinda , Rodrigues Paula 
Published: June 2019

Purpose
This paper aims to investigate the mediating effect of brand love on purchase intention and word-of-mouth through mystery, sensuality and intimacy as brand image dimensions in the context of neo-luxury brands. It also explores the moderating effect of duration and intensity of consumer-brand relationships on brand image dimensions.

Design/methodology/approach
The data collection was done via an online survey of a representative group of Millennials. Data analysis was performed using structural equation modeling and multi-group analysis.

Findings
The paper suggests that brand love mediates the relationship between brand image, purchase intention and word-of-mouth for both Apple and Michael Kors brands. This study also identifies differences in the effects of intimacy, sensuality and mystery on brand love. Additionally, it is demonstrated that the moderation effect of intensity and duration of consumer-brand relationships varies among the two neo-luxury brands.

Research limitations/implications
Further research should aim at investigating other categories of products and services in the field of neo-luxury, as this study focus on fashion and mobile brands. Other antecedents and outcomes of brand love should also be evaluated, as well as other moderating variables.

Originality/value
This paper contributes to the fast-growing consumer-brand relationships literature by exploring the role of brand love in the context of the emergent neo-luxury paradigm. It also intends to provide a better understanding of how to build and nurture an effective brand image through a multidisciplinary approach that combines mystery, sensuality and intimacy.
Role of consumer vanity and the mediating effect of brand consciousness in luxury consumption
Authors: Sharda Nikita , Bhat Anil 
Published: June 2019

Purpose
There has been substantial research on luxury globally, but there is a dearth of studies empirically investigating the key relationships affecting luxury consumption. The aim of this paper is to consider the role of consumer vanity and brand consciousness and to set their relationships in context of luxury consumption.

Design/methodology/approach
To measure consumer vanity, brand consciousness, attitude towards luxury brands and purchase intentions, pre-established scale items were adopted. Self-administered questionnaires were distributed through luxury exhibitions and festivals in major cities of India. A sample of n = 342 luxury consumers was analysed using structural equation modelling.

Findings
The findings support that brand consciousness is mediating the relationship between consumer vanity and luxury consumption. Luxury consumers are primarily driven by achievement vanity. They are likely to evaluate luxury brands based on their price, fame and their ability to portray their professional achievements. They incur unreasonable costs to acquire the expensive, famous and prestigious luxury brands and conspicuously consume them to display their success and accomplishments.

Research limitations/implications
The study provides an in-depth explanation of how consumer vanity is leading to consumption of luxury brands. The marketers may benefit by focussing on promotion of their brand's symbols and logos than on specific product features.

Originality/value
This is the first empirical examination understanding the mediating effect of brand consciousness as a mediator between consumer vanity and luxury consumption.
The individualism of motivation
Authors: Mayo Andrew 
Published: June 2019

Purpose
The purpose of this paper is to examine the components that drive employee engagement and show how important it is to understand the individualism of motivation as against generic assumptions.

Design/methodology/approach
This paper defines employee engagement and takes four drivers that influence it in turn. These are analysed and discussed, particularly as to the individualistic elements of them. Two approaches to understanding individual goals and priorities are illustrated.

Findings
There are four drivers of engagement, namely, the absence of dissatisfaction or irritation factors, intrinsic motivation (inner driven) and extrinsic motivation (external stimulation) and personal well-being. Each of these have highly individualistic elements, and models based on a generic human condition do not work effectively. Two instruments for understanding this individualism are illustrated, one based on goal theory and another based on the psychological contract.

Practical implications
Many motivational efforts fail because of an assumed commonality in what motivates people. The reality is that different personalities and different personal goals and values require individual approaches. Successful engagement demands that leader/managers make it a priority to understand each one of their people in these terms.

Originality/value
This paper is based mostly on the writing, models and experience of the author.
Effectiveness of spontaneous ovulation as monitored by urinary luteinising hormone versus induced ovulation by administration of human chorionic gonadotrophin in couples undergoing gonadotrophin‐stimulated intrauterine insemination: a randomised controlled trial
Authors: Thomas S , Sebastian T , Karthikeyan M , Mangalaraj AM , Aleyamma TK , Kamath MS 
Published: June 2019

ObjectiveTo compare effectiveness of spontaneous ovulation monitored by urinary luteinising hormone (LH) versus induced ovulation by administration of human chorionic gonadotrophin (hCG) in couples undergoing gonadotrophin‐stimulated intrauterine insemination (IUI).DesignRandomised controlled trial.SettingUniversity‐level infertility unit.PopulationCouples with unexplained infertility, mild endometriosis, mild male factor infertility and polycystic ovarian syndrome.MethodsCouples were randomised to an LH group (Group A), in which urinary LH was measured daily to detect spontaneous ovulation, or an hCG group (Group B), in which urinary hCG was administered as a trigger.Main outcome measuresClinical pregnancy rate. Secondary outcomes – ongoing pregnancy, live birth, multiple pregnancy and miscarriage rates.ResultsA total of 392 couples were randomised with 196 in each arm. The clinical pregnancy rate per woman randomised was 14/196 (7.1%) in the LH arm versus 15/196 (7.6%) in the hCG arm (P = 0.847, which was not statistically significant). Similarly, the ongoing pregnancy rates [13/196 (6.6%) versus 14/196 (7.1%); P = 0.84] and the live birth rates [13/196 (6.6%) versus 14/196 (7.1%); P = 0.84] between the two groups did not show any significant difference. The duration of stimulation and gonadotrophin dosage also did not differ significantly between the two methods.ConclusionThere was no significant difference in clinical pregnancy rates when urinary LH and hCG trigger were compared as methods to time insemination in women undergoing gonadotropin‐stimulated IUI.Tweetable abstractA randomised controlled study showing similar effectiveness between two different methods of timing IUI.
Gaseous pollutant exposure affects semen quality in central China: a cross‐sectional study
Authors: Wang X. , Tian X. , Ye B. , Zhang Y. , Li C. , Liao J. , Zou Y. , Zhang S. , Zhu Y. , Yang J. , Ma L. 
Published: June 2019

AbstractBackgroundLimited studies have explored the association between gaseous pollutant exposures and male reproductive outcomes, and findings remained inconsistent.ObjectivesTo evaluate the potential association between gaseous pollutants and semen quality within different exposure windows.Materials and MethodsWe adopted semen quality data of 1852 subjects who attended the Reproductive Medicine Center of Renmin Hospital at Wuhan University during January 1st, 2013, to August 3rd, 2015. A generalized linear model was employed to assess the relationship between each exposure variable and sperm parameters in different exposure windows.ResultsSO2 exposure with lag 0–90 days was significantly associated with decreased sperm concentration (β: −1.362; 95% CI: −1.844, −0.879), sperm count (β: −2.979; 95% CI: −4.267, −1.691), and PR (β: −0.551; 95% CI: −0.710, −0.393). Similar trends were observed for SO2 exposure with three other key periods (lag 0–9, 10–14, and 70–90 days). NO2 exposure with lag 0–90 days was also associated with decreased sperm concentration (β: −0.517; 95% CI: −1.006, −0.027), sperm count (β: −1.914; 95% CI: −3.214, −0.615), and PR (β: −0.264; 95% CI: −0.425, −0.102). No relationship between gaseous pollutant exposure and ejaculate volume was observed in any exposure window.Discussion and ConclusionOur study indicated a strong adverse effect of gaseous pollutants on semen quality outcomes during the sperm development. Gaseous pollution exposure appeared to be more detrimental in the initial phase of spermatogenesis.
Rapid decline in estimated glomerular filtration rate is common in adults with sickle cell disease and associated with increased mortality
Authors: Derebail Vimal K. , Zhou Qingning , Ciccone Emily J. , Cai Jianwen , Ataga Kenneth I. 
Published: June 2019

SummaryWe evaluated the prevalence of rapid decline in kidney function, its potential risk factors and influence upon mortality in sickle cell disease (SCD) in a retrospective single‐center study. Rapid decline of kidney function was defined as estimated glomerular filtration rate (eGFR) loss of >3·0 ml/min/1·73 m2 per year. A multivariable logistic regression model for rapid eGFR decline was constructed after evaluating individual covariates. We constructed multivariate Cox‐regression models for rapid eGFR decline and mortality. Among 331 SCD patients (median age 29 years [interquartile range, IQR: 20, 41]; 187 [56·5%] female) followed for median 4·01 years (IQR: 1·66, 7·19), rapid eGFR decline was noted in 103 (31·1%). History of stroke (odds ratio [OR]: 2·91, 95% confidence interval [CI]: 1·25–6·77) and use of angiotensin converting enzyme inhibitors/angiotensin receptor blockers (OR: 3·17, 95% CI: 1·28–7·84) were associated with rapid eGFR decline. The rate of eGFR change over time was associated with mortality (hazard ratio [HR]: 0·99, 95% CI: 0·984–0·995, P = 0·0002). In Cox‐regression, rapid eGFR decline associated with mortality (HR: 2·07, 95% CI: 1·039–4·138, P = 0·04) adjusting for age, sex and history of stroke. Rapid eGFR decline is common in SCD and associated with increased mortality. Long‐term studies are needed to determine whether attenuating loss of kidney function may decrease mortality in SCD.
The hidden costs of employee drinking: A quantitative analysis
Authors: Sullivan Trudy , Edgar Fiona , McAndrew Ian 
Published: June 2019

AbstractIntroduction and AimsAlcohol use impacts workplace productivity in terms of absence and reduced performance by employees. This study's aims were to estimate the cost of lost productivity associated with alcohol use in New Zealand and to describe and quantify its impact on employers.Design and MethodsAn online survey was completed by 800 New Zealand employees and 227 employers across a range of industries. The costs of lost productivity directly attributable to alcohol use were estimated using days off work (absenteeism), lost hours of productive time while at work (presenteeism) and hours spent by employers dealing with alcohol‐related issues. Ordinal logistic regression was used to explore the association between employee characteristics and reduced workplace productivity associated with alcohol consumption.ResultsThe estimated annual average cost of lost productivity per employee was NZ$1097.71 (NZ$209.62 absenteeism, NZ$888.09 presenteeism) and NZ$134.62 per employer. At a population level this equates to approximately NZ$1.65 billion per year. The significant predictors of reduced workplace performance were being younger (less than 25 years), male, having a stressful job and drinking more than the recommended standard number of drinks per session.Discussion and ConclusionsConsidering absenteeism costs alone will substantially underestimate the total productivity loss associated with alcohol use. Designing and effectively targeting a set of multifaceted policies to engineer change at both the workplace and societal levels will assist in reducing the costs of lost productivity.
Left ventricular vortex formation in preterm infants assessed by blood speckle imaging
Authors: de Waal Koert , Crendal Edward , Boyle Andrew 
Published: June 2019

AbstractBackgroundA vortex is a rotational fluid structure formed by shearing of fluid layers. It forms during diastole in the left ventricle (LV) and helps redirect flow to the LV outflow tract for ejection, optimizing energy conservation. The aim of this study was to demonstrate the feasibility of detecting and analyzing LV vortices using a new ultrasound technique known as blood speckle imaging (BSI).MethodsConventional and BSI parameters were acquired in preterm infants referred for echocardiography. BSI feasibility and reliability were explored using highest frequency settings and optimized Nyquist limits. Vortex area was determined by tracing the outer vortex ring at maximum area. Peak vortex formation time (PVFT) was determined at time of maximum vortex area relative to the R‐wave, and vortex duration from frame‐by‐frame analysis of first appearance to vortex degradation.ResultsLeft ventricle vortices were detected in 49 of the 50 preterm infants (weight 500–2020 g) with excellent intra‐ and inter‐observer reliability. Mean vortex area indexed to LV area was 0.19 (0.08). Peak vortex formation time was at 87 (7)% of the cardiac cycle, and vortex duration lasted 13 (4)% of the cardiac cycle. Vortex area correlated positively with LV length, end‐diastolic dimension, end‐diastolic volume, mitral annular (R +0.42, +0.50, +0.47, +0.50, all P < 0.01), and transmitral Vti (R +0.37, P < 0.01). PVFT correlated negatively with E, EA, and Ee’ (R −0.42, −0.47, −0.47, all P < 0.01).ConclusionLeft ventricle vortex formation can be analyzed with two‐dimensional BSI and has the potential to complement existing parameters of cardiac health.
A case of prosthetic aortic valve dehiscence due to infective endocarditis without paravalvular regurgitation
Authors: Buggey Jonathan , Hoit Brian D. 
Published: June 2019

AbstractAortic prosthetic valve endocarditis is often a challenging disease process that carries high morbidity and mortality. Echocardiography is widely used to identify infected valves and associated complications. One major complication of an infection involving the aortic annulus is dehiscence of the prosthetic valve from the aortic root and is usually associated with paravalvular regurgitation. Here, we present a rare case of complete prosthetic valve dehiscence without paravalvular regurgitation on transthoracic and transesophageal echocardiography.
The dilemma to diagnose Wilson disease by genetic testing alone
Authors: Stättermayer Albert Friedrich , Entenmann Andreas , Gschwantler Michael , Zoller Heinz , Hofer Harald , Ferenci Peter 
Published: June 2019

AbstractBackgroundWilson disease (WD) is an autosomal recessive disorder of hepatic copper excretion. About sixty per cent of patients present with liver disease. WD is considered a fatal disease if undiagnosed and/or untreated but recent data indicate that disease penetrance may not be 100%.Materials and MethodsAll patients underwent liver biopsy as part of the diagnostic workup. Genetic testing for ATP7B was performed by Sanger sequencing.ResultsWe report on a large family with multiple affected siblings. The first patient (male, 31 years) underwent orthotopic liver transplantation (OLT) because of fulminant WD. He was homozygous for p.G710A. One asymptomatic brother (37 years) had the same mutation. He is doing well on chelation therapy. Fifteen years later, a second‐degree sibling (female, 16 years) presented with fulminant WD and underwent OLT. She was compound heterozygote (p.G710A/p.G710S). Further family screening revealed a third mutation (p.V536A) in a female (21 years) and male (16 years) compound‐heterozygote sibling (p.G710A/p.V536A). In both, serum ceruloplasmin and 24‐hour urinary copper excretion were normal. Liver biopsy showed normal histology and a quantitative hepatic copper content within the normal range or only slightly elevated (19 and 75 μg/g dry weight, respectively). No decoppering treatment was initiated so far.ConclusionGenetic testing alone is not always sufficient to diagnose WD in asymptomatic patients, and human mutation databases should be used with caution. Even patients carrying two disease‐causing mutations do not necessarily have demonstrable alteration of copper metabolism. Asymptomatic siblings diagnosed by genetic screening require further testing before initiating treatment.
Not berry hungry? Discovering the hidden food sources of a small fruit specialist, Drosophila suzukii
Authors: Stockton Dara G. , Brown Rachael , Loeb Gregory M. 
Published: June 2019

1. Although polyphagy is widespread among Drosophila, some specialist species have evolved in response to resource competition and other selection factors favouring niche separation. The small fruit specialist Drosophila suzukii Matsumura has evolved a unique serrated ovipositor that allows it to access ripening fruit, a niche unavailable to most Drosophila. However, it is unclear whether ancestral traits (the use of non‐fruit resources) are maintained in this specialist species.2. In this study, maternal preferences and offspring fitness in response to novel apple, mushroom, and bird manure‐based diets were investigated by comparing oviposition and offspring survival and development on various diets. The effect of those diets on survival at cool temperatures and the effect of natal environment/previous exposure on adult preferences were evaluated.3. Female D. suzukii accepted non‐fruit diets such as mushroom and bird manure, and offspring completed their larval development on all diets tested. However, D. suzukii did not perform well on diets that included bird manure. By contrast, combinational apple/mushroom diets were associated with greater oviposition, lower mortality, faster development, and larger offspring than other diets. These diets were also associated with increased resistance to cold stress, and preference for these diets was positively affected by previous feeding experience.4. These data suggest that D. suzukii may use non‐fruit resources when preferred resources are scarce. Given that this pest is adapted to temperate climates, alternative resources might provide seasonal nutritional support when fruit resources are not temporally available, although field data are needed to support this hypothesis.
Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy
Authors: Petukhova Lynn , Patel Aakash V. , Rigo Rachel K. , Bian Li , Verbitsky Miguel , Sanna‐Cherchi Simone , Erjavec Stephanie O. , Abdelaziz Alexa R. , Cerise Jane E. , Jabbari Ali , Christiano Angela M. 
Published: June 2019

AbstractAlopecia areata (AA) is a highly prevalent autoimmune disease that attacks the hair follicle and leads to hair loss that can range from small patches to complete loss of scalp and body hair. Our previous linkage and genome‐wide association studies (GWAS) generated strong evidence for aetiological contributions from inherited genetic variants at different population frequencies, including both rare mutations and common polymorphisms. Additionally, we conducted gene expression (GE) studies on scalp biopsies of 96 patients and controls to establish signatures of active disease. In this study, we performed an integrative analysis on these two datasets to test the hypothesis that rare CNVs in patients with AA could be leveraged to identify drivers of disease in our AA GE signatures. We analysed copy number variants (CNVs) in a case‐control cohort of 673 patients with AA and 16 311 controls independent of the case‐control cohort of 96 research participants used in our GE study. Using an integrative computational analysis, we identified 14 genes whose expression levels were altered by CNVs in a consistent direction of effect, corresponding to gene expression changes in lesional skin of patients. Four of these genes were affected by CNVs in three or more unrelated patients with AA, including ATG4B and SMARCA2, which are involved in autophagy and chromatin remodelling, respectively. Our findings identified new classes of genes with potential contributions to AA pathogenesis.