bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women's initial experiences of their appearance after mastectomy and/or breast reconstruction: A qualitative study
Authors: Herring Beth , Paraskeva Nicole , Tollow Philippa , Harcourt Diana 
Published: August 2019

AbstractObjectiveSurgical procedures intended to treat breast cancer or reduce risk of developing the disease typically result in changes to appearance and scarring of the breast area, and any donor sites. The longer‐term impact of these changes on body image and quality of life are well documented, but research in this field has failed to explore women's initial experiences of their appearance after surgery. This study used a qualitative approach to gain insight and better understand the experiences of women at this time point in their treatment pathway.MethodsWomen (n=128) who had undergone mastectomy and/or breast reconstruction following a diagnosis of breast cancer or to reduce their risk of developing the disease completed an online survey. Open‐ended questions asked participants about their experiences when seeing the postsurgical appearance of their breast/breast area (and donor site, if relevant) for the first time, and the support available to them.ResultsThematic analysis generated four key themes: “preparedness and support,” “first thoughts and emotions,” “loss and grief,” and “the reaction of others.”ConclusionsThere was considerable variability in women's experiences. Some felt prepared and emotionally supported at this time, whilst others felt this element of care was missing. The findings suggest that there is a need to ensure all women are informed and have the necessary support when looking at the results of their surgery for the first time. Areas for improvement were proposed, including preoperative discussions, increased preparation and support. This could potentially contribute to better patient outcomes overall.
Neural adaptive global stability control for robot manipulators with time‐varying output constraints
Authors: Fan Yongqing , Kang Tongtong , Wang Wenqing , Yang Chenguang 
Published: August 2019

SummaryIn this paper, a novel adaptive control scheme is proposed based on radial basis function neural network (RBFNN). The considered system is deduced by the structure of RBFNN with nonzero time‐varying parameter that installed in the fore‐end and terminal of RBFNN. With this structure and the Taylor expansion of any smooth continuous nonlinear function, a universal approximation of RBFNN is addressed according to the analysis of the character of continuous homogenous function and the Euler's theorem. The approximation accuracies can be adjusted online by the nonzero time‐varying parameter in the device with the degree of continuous homogenous function, which expand the semiglobally stability to global stability over conventional neural controller design approaches. Based on the theory analysis of barrier Lyapunov function, the violation of time‐varying constraints can be subjugated without wrecked. Finally, simulation results are carried out to verify the effectiveness by the design methods.
Predicting Functional Responses of Progenitor Cell Exosome Potential with Computational Modeling
Authors: Trac David , Hoffman Jessica R. , Bheri Sruti , Maxwell Joshua T. , Platt Manu O. , Davis Michael E. 
Published: August 2019

AbstractCongenital heart disease can lead to severe right ventricular heart failure (RVHF). We have shown that aggregated c-kit+ progenitor cells (CPCs) can improve RVHF repair, likely due to exosome-mediated effects. Here, we demonstrate that miRNA content from monolayer (2D) and aggregated (3D) CPC exosomes can be related to in vitro angiogenesis and antifibrosis responses using partial least squares regression (PLSR). PLSR reduced the dimensionality of the data set to the top 40 miRNAs with the highest weighted coefficients for the in vitro biological responses. Target pathway analysis of these top 40 miRNAs demonstrated significant fit to cardiac angiogenesis and fibrosis pathways. Although the model was trained on in vitro data, we demonstrate that the model can predict angiogenesis and fibrosis responses to exosome treatment in vivo with a strong correlation with published in vivo responses. These studies demonstrate that PLSR modeling of exosome miRNA content has the potential to inform preclinical trials and predict new promising CPC therapies. Stem Cells Translational Medicine 2019;8:1212–1221
Quantifying degrees of necessity and of sufficiency in cause‐effect relationships with dichotomous and survival outcomes
Authors: Gleiss Andreas , Schemper Michael 
Published: August 2019

We suggest measures to quantify the degrees of necessity and of sufficiency of prognostic factors for dichotomous and for survival outcomes. A cause, represented by certain values of prognostic factors, is considered necessary for an event if, without the cause, the event cannot develop. It is considered sufficient for an event if the event is unavoidable in the presence of the cause. Necessity and sufficiency can be seen as the two faces of causation, and this symmetry and equal relevance are reflected by the suggested measures. The measures provide an approximate, in some cases an exact, multiplicative decomposition of explained variation as defined by Schemper and Henderson for censored survival and for dichotomous outcomes.The measures, ranging from zero to one, are simple, intuitive functions of unconditional and conditional probabilities of an event such as disease or death. These probabilities often will be derived from logistic or Cox regression models; the measures, however, do not require any particular model.The measures of the degree of necessity implicitly generalize the established attributable fraction or risk for dichotomous prognostic factors and dichotomous outcomes to continuous prognostic factors and to survival outcomes. In a setting with multiple prognostic factors, they provide marginal and partial results akin to marginal and partial odds and hazard ratios from multiple logistic and Cox regression.Properties of the measures are explored by an extensive simulation study. Their application is demonstrated by three typical real data examples.
Synthesis, Structure and Magnetic Properties of Copper(II) Complexes of Diphenyl‐(1‐propylbenzimidazol‐2‐yl)methanol
Authors: Burlov Anatolii S. , Koshchienko Yurii V. , Vlasenko Valery G. , Bogomyakov Artem S. , Kolodina Alexandra A. , Zubavichus Yan V. , Lazarenko Vladimir A. , Khrustalev Victor N. 
Published: August 2019

AbstractTwo types of binuclear copper complexes [LCuN3]2 and [LCuNO3]2.of bidentate ligand ‐ diphenyl‐(1‐propylbenzimidazol‐2‐yl)methanol (HL) in the 4:1 ratio were synthesized. The crystal structure of copper complexes shows a centrosymmetric dimeric binuclear complex with two Cu2+ cations bridged by two oxygen atoms from two organic ligands. In the complexes, a very strong antiferromagnetic exchange interaction between copper atoms is observed.
Copper‐Phosphine Supported Fe3O4@SiO2 as a Novel Reusable Nanocatalyst‐Catalyzed Tandem Reaction of Indole and Alcohols to Bis(indolyl)methanes under Blue LED Light
Authors: Mohammadi Hadi , Shaterian Hamid Reza 
Published: August 2019

AbstractNano Fe3O4@SiO2@TPP−Cu as a novel heterogeneous nanocatalyst was prepared and authenticated by usual analytical and spectroscopic techniques. The prepared Fe3O4@SiO2@TPP−Cu was applied to preparation of bis(indolyl)methane derivatives via a three‐component reaction of aromatic alcohols with indoles under blue led lights. The advantages of this method are the selective oxidation of alcohols under mild conditions. In addition, the recycling studies revealed that catalyst could be easily recovered using an external magnet and reused for five times without significant loss of its catalytic activity.
Calcium‐Induced Photoluminescence Quenching of Graphene Quantum Dots in Hard Water: A Quick Turn‐Off Sensing Approach
Authors: Mishra Praveen , Bhat Badekai Ramachandra 
Published: August 2019

AbstractThe photoluminescence of graphene quantum dots (GQD) is widely explored for sensory applications. Among various metal ions to be detected in aqueous bodies, Ca2+ ions are often neglected which is evident from the lack of literature. However, owing to booming industrialization, the available potable water is mostly crossing the prescribed hardness limits. Presented report summarize the synthesis of GQD via modified hydrothermal cutting of graphene oxide, which was further employed for sensing Ca2+ ions in hard water samples. The as synthesized GQD exhibited its characteristic blue photoluminescence on excitation with longwave UV (λ ≈ 365 nm) which was suppressed on the introduction of Ca2+ ions. The GQD as photoluminescent probe determined the concentration of Ca2+ ion in water with an accuracy of 96.74% ± 3.26%. The LOD of the reported method was found to be 5 μM and it was sensitive towards Ca2+ ions in the presence of interfering ions such as Al3+, Mg2+, and K+ which are commonly found in hard water samples. Therefore, the determination of hardness of water w.r.t Ca2+ using GQD based PL turn off sensing is a quick, viable and economical method.
Bemessung von Befestigungen mit elastischen Ankerplatten unter Zug‐ und Biegebeanspruchung
Authors: Li Longfei 
Published: August 2019

AbstractDie Bemessung von Befestigungen mit Ankerplatten unter Zug‐ und Biegebeanspruchung nach FprEN 1992‐4 (EC2, Teil 4) [1] setzt voraus, dass die Ankerzugkräfte von der Ankerplatte auf Beton eben verteilt werden. Um diese Voraussetzung zu erfüllen, müssen die Ankerplatten ausreichend steif bzw. biegestarr sein. Die Bedingung für eine biegestarre Ankerplatte ist seit Jahrzehnten ohne zufriedenstellende Lösung untersucht und diskutiert worden. Die neuesten Untersuchungen zeigen, dass die erforderliche Dicke für die biegestarre Ankerplatte in vielen Anwendungsfällen so groß sein kann, dass sie für die Praxis kaum mehr Bedeutung hat. Dies bestätigt die Aussagen von Schneider von 1999 und 2014 [2, 3], dass die Annahme der biegestarren Ankerplatten für die Berechnung der Ankerzugkräfte bei normalen Plattendicken unbrauchbar zu sein scheint. Das heißt, es ist unverzichtbar, dass die elastischen Ankerplatten mit normalen Dicken in der Praxis verwendet werden und die Ankerplatten‐Biegeverformungen in der Bemessung berücksichtigt werden müssen.Im vorliegenden Aufsatz werden die Vorschriften nach FprEN 1992‐4 [1] zur Ankerzugkraftermittlung analysiert. Die Besonderheiten für die Bemessung von Befestigungen mit elastischen Ankerplatten werden durch Rechenbeispiele mit einer herstellerunabhängigen Bemessungssoftware für Kopfbolzen und Dübel [4] erläutert und diskutiert.
Die eisernen Dächer und Decken der Eremitage in St. Petersburg
Authors: Lorenz Werner 
Published: August 2019

AbstractAb 1838 innerhalb gut eines Jahrzehnts errichtet, müssen die eisernen Dach‐ und Deckentragwerke der Eremitage‐Bauten in St. Petersburg heute aufgrund ihrer Ausdehnung, ihres Variantenreichtums und der noch in großen Bereichen originalen Substanz als einzigartiges Zeugnis aus den Anfängen des Stahlbaus gelten. Sie geben Einblick in die Konstruktionspraktiken einer offenen, noch regellosen Zeit, in der man in Europa erst begann, die Möglichkeiten des Bauens mit Schmiedeeisen und Stahl systematisch zu erkunden. Im Rahmen eines von der DFG geförderten Verbundprojekts wurden sie erstmals archivarisch und in situ detailliert untersucht. Am Beispiel des Winterpalastes stellt der Beitrag nach einer kurzen Typologie der Haupttragwerke zunächst die Organisation dieser Großbaustelle vor, auf der für die Lieferung der Eisenkonstruktionen ein umfassendes Qualitätskontrollsystem entwickelt wurde. Die Untersuchung der Konstruktionsprozesse zeigt auf, dass in Entwurf, Bemessung und Legitimation der neuartigen Tragwerke Erfahrung und „stilles Wissen” ebenso einflossen wie versuchsgestützte Tragsicherheitsnachweise und erste statische Berechnungen und nicht zuletzt baubegleitende Updates aus Versagensfällen und Einstürzen.
Die Stahlbauten der Moderne und das Wüstenrot‐Hochhaus in Ludwigsburg
Authors: Böttner Cornelia , Hauke Bernhard 
Published: August 2019

AbstractIm Zuge der Bauhausbewegung und des Advents der Moderne entwickelt sich mit den neuen industriellen und technischen Möglichkeiten eine eigene Ästhetik. Der Stahl bleibt mit seiner Tragstruktur unsichtbar, doch wird er zum versteckten Helfer moderner Raumideen und einer Industrialisierung des Bauens. Die Weissenhofsiedlung in Stuttgart zeigt dies exemplarisch. Weiters wird mit Entwurf und Tragwerksplanung des Wüstenrot‐Hochhauses in Ludwigsburg (1953) von Richard Döcker und Walter Wrycza ein Stahlskeletthochhaus in ebendieser Tradition vorgestellt.
Toy models of holographic duality between local Hamiltonians
Authors: Kohler Tamara , Cubitt Toby 
Published: August 2019

Abstract

Holographic quantum error correcting codes (HQECC) have been proposed as toy models for the AdS/CFT correspondence, and exhibit many of the features of the duality. HQECC give a mapping of states and observables. However, they do not map local bulk Hamiltonians to local Hamiltonians on the boundary. In this work, we combine HQECC with Hamiltonian simulation theory to construct a bulk-boundary mapping between local Hamiltonians, whilst retaining all the features of the HQECC duality. This allows us to construct a duality between models, encompassing the relationship between bulk and boundary energy scales and time dynamics.
It also allows us to construct a map in the reverse direction: from local boundary Hamiltonians to the corresponding local Hamiltonian in the bulk. Under this boundary-to-bulk mapping, the bulk geometry emerges as an approximate, low-energy, effective theory living in the code-space of an (approximate) HQECC on the boundary. At higher energy scales, this emergent bulk geometry is modified in a way that matches the toy models of black holes proposed previously for HQECC. Moreover, the duality on the level of dynamics shows how these toy-model black holes can form dynamically.
Exploring prescriber perspectives toward nurses’ active involvement in antimicrobial stewardship: A qualitative study
Authors: Greendyke William G. , Shelley Alexandra N. , Zachariah Philip , Yoko Furuya E. , Carter Eileen J. 
Published: August 2019

AbstractLittle is known about prescribers’ attitudes regarding clinical nurses and antimicrobial stewardship. We conducted focus groups of prescribers and inquired about attitudes regarding nurses and stewardship. During 6 focus groups, prescribers were receptive to nursing involvement in stewardship activities, but noted structural barriers and knowledge gaps that should be addressed.
Stepping back to look ahead: neuter encapsulation and referent extension in counter-argumentative and causal relations in Spanish
Authors: PARODI GIOVANNI , JULIO CRISTOBAL , NADAL LAURA , CRUZ ADRIANA , BURDILES GINA 
Published: August 2019

abstractIn discourse comprehension, if all goes well, people tend to create a rich and coherent mental representation of the events described in the text. To do so, referential and relational coherence must be established in order to construct a connected discourse. The objective of this follow-up eye-tracking study (N = 72) is to explore the existence of an interaction effect between two factors: (a) the extension of the referent (short and long antecedent), and (b) the semantic relation (counter-argumentativea pesar de, and causalpor), when processing the neuter pronounelloin texts written in Spanish. No previous study has systematically compared the on-line processing of texts in which different extensions of the encapsulated anaphoric antecedent by the neuter pronounello(‘this’ or ‘it’ in English) are presented in diverse marked semantic relations (causal and counter-argumentative). Based on three eye-tracking measures, we found distinctive patterns of reading behavior when anaphoric neuter reference and semantic relations must be processed conjointly in order to construct a coherent mental representation. The main findings show that reading longer and more complex antecedents encapsulated by the neutral pronounselloexerts more cognitive effort in late processing (Look Back measure), particularly when simultaneously and in the same discourse construction there is an explicitly marked counter-argumentative semantic relation. Implications for theories of referential and relational coherence are discussed.
X-ray diffraction has limited applicability in investigation of milk tampering
Authors: Battaglini Ana Paula Pavão , Urbano Alexandre , Beloti Vanerli , Rios Edson Antonio , Ramos Pereira Juliana , Fagnani Rafael 
Published: August 2019

AbstractThe aim of this work was to use X-ray diffraction to identify substances used for adulteration of raw milk and to determine if crystallographic analysis can detect extraneous substances in milk. Two unknown substances were sent anonymously by employers linked to the dairy chain, who claimed that they were added directly in milk prior to water addition by truck drivers. The samples were analyzed by X-ray diffraction and submitted to physicochemical analysis. The first substance was identified by X-ray diffraction as sodium citrate, complying with its physicochemical attributes, such as the powerful ability to decrease the freezing point. The second substance was identified by X-ray diffraction as sucrose and this result was also in agreement with its ability to increase the density, decrease the freezing point and finally, to be positive for sucrose in the resorcinol qualitative test. To evaluate if X-ray diffraction can detect extraneous substances already mixed in milk, fresh raw milk samples tampered with urea, sodium hydroxide, sodium citrate and sucrose were freeze dried and analyzed by X-ray diffraction, with no detection of any extraneous substances at any percentage. This is the first report of attempted diagnosis of extraneous substances in milk by X-ray diffraction. However, this technique can be useful only when applied to identify substances used for adulteration prior to its dilution in milk, since the amorphous nature of milk seems to be a limitation for the accurate detection of extraneous substances.
Is food insecurity related to health-care use, access and absenteeism?
Authors: Melo António , Matias Maria Ana , Dias Sara S , Gregório Maria João , Rodrigues Ana M , de Sousa Rute Dinis , Canhão Helena , Perelman Julian 
Published: August 2019

AbstractObjective:Food insecurity (FI) is defined as uncertain access to healthy food in quantity and quality. We hypothesize that FI may be associated with greater health-care use and absenteeism because it may amplify the effect of diseases; also, FI may be associated with reduced health-care access because it reflects economic vulnerability. The present study estimates the association between FI and health-care use and access, and absenteeism.Design:Cross-sectional data collected in 2015–2016. Health-care use was measured as the number of consultations, taking any drug and having been hospitalized in the past year. Health-care access was measured by the suspension of medication and having fewer consultations due to financial constraints. Absenteeism was measured by the weeks of sickness leave. Binary variables were modelled as a function of FI using logistic regressions; continuous variables were modelled as a function of FI using negative binomial and zero-inflated negative binomial regressions. Covariates were included sequentially.Setting:Portugal.Participants:Non-institutionalized adults from the EpiDoc3 cohort (n 5648).Results:FI was significantly associated with health-care use before controlling for socio-economic conditions and quality of life. Moderate/severe FI was positively related to the suspension of medicines (adjusted OR = 4·68; 95 % CI 3·11, 6·82) and to having fewer consultations (adjusted OR = 3·98; 95 % CI 2·42, 6·37). FI and absenteeism were not significantly associated.Conclusions:Our results support the hypothesis that FI reflects precariousness, which hinders access to health care. The greater use of health care among food-insecure people is explained by their worse quality of life and lower socio-economic condition, so that the specific role of poor nutrition is unclear.
The importance of the cultural dimension of food in understanding the lack of adherence to diet regimens among Mayan people with diabetes
Authors: Juárez-Ramírez Clara , Théodore Florence L , Villalobos Aremis , Allen-Leigh Betania , Jiménez-Corona Aida , Nigenda Gustavo , Lewis Sarah 
Published: August 2019

AbstractObjective:To understand non-adherence to medically recommended diets among Mayans with diabetes.Design:Using partially sequential mixed methods, questionnaires, semi-structured brief and in-depth interviews were applied. Questionnaire data were analysed with Pearson’s χ2 and Student’s t tests and qualitative interviews with grounded theory microanalysis.Setting:Rural, predominantly Mayan communities in Chiapas, Quintana Roo and Yucatan, Mexico, 2008–2012.Participants:Purposive sample of Mayans with type 2 diabetes; using public health care; 168 women and twenty-seven men; age 21–50+ years.Results:Participants understood diabetes as caused by negative emotions, divine punishment, revenge via spells, chemicals in food and high sugar/fat consumption. Eliminating corn, pork, sugary beverages and inexpensive industrialized foods was perceived as difficult or impossible. More Mayans reporting not understanding physician instructions (30 v. 18 %) reported difficulty reducing red meat consumption (P = 0·051). Non-adherence was influenced by lack of patient–provider shared knowledge and medical recommendations misaligned with local culture. Men whose wives prepared their meals, women who liked vegetables and young adults whose mothers prepared their meals reported greater adherence to dietary recommendations. Partial adherents said it made life tolerable and those making no physician-recommended dietary changes considered them too restrictive (they meant ‘starving to death’). Over half (57 %) of participants reported non-adherence; the two principal reasons were dislike of recommended foods (52·5 %) and high cost (26·2 %).Conclusions:Adherence to dietary regimens in diabetes treatment is largely related to social and cultural issues. Taking cultural diversity, food preferences, local food availability and poverty into consideration is essential when developing health-promotion activities related to diabetes.