bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Drilling Force on Delamination of Abaca/Kenaf/Carbon Fiber Reinforced Hybrid Composite
Authors: Venkatasudhahar M. , Velu R. 
Published: February 2019

Background:
Natural fiber reinforced materials with polymer matrix finds many applications
in industries due to its excellent property. Fiber laminate composite materials have been researched
around the globe and were tested to determine its beneficial properties for specific purposes.
These composite materials have improved to withstand external loads. However, drilling of composite
has remained a difficult task because of its anisotropic material properties.

Methods:
In this study abaca and kenaf woven mat with the carbon woven mat are laminated using
epoxy resin (HY 951) and hardener (LY556) as matrix element while preparing the hybrid composite
materials. The drilling operations are carried out using automatic feed computer controlled vertical axis
drilling machine.

Results:
It is found that the drilling force, delamination peel up and push out for the composite material
depended on feed rates, drill bit diameters and speeds respectively. The optimal input parameters are
obtained using Taguchi L27 orthogonal array, Response Surface Methodology (RSM) and Analysis Of
Variance (ANOVA) methods. It is observed that lower feed, smaller drill diameter and moderate speed
provided high quality drilled hole. The drilled-hole quality, drilling damages are observed by using
profile projector.

Conclusion:
The following conclusion can be drawn from the present investigation on drilling of reinforced
composite materials drilled in different conditions. Feed rate is the important factor compared to
the feed and the tool diameter. When feed rate is increased, thrust force also increases. However, thrust
force decreases when the cutting speed increases. Feed influenced the thrust force instead of speed and
torque during drilling. The drilling induced damages are minimum during lower feed and lower diameter
drill. Hence, lower drill diameter, lower feed rate and medium speed are more suitable for drilling
the hybrid composites.
Utility of Whole-Genome Next-Generation Sequencing of Plasma in Identifying Opportunistic Infections in HIV/AIDS
Authors: Zhou Yang , Hemmige Vagish , Dalai Sudeb C. , Hong David K. , Muldrew Kenneth , Mohajer Mayar Al 
Published: February 2019

Background:AIDS-associated Opportunistic Infections (OIs) have significant morbidity and mortality and can be diagnostically challenging, requiring invasive procedures as well as a combination of culture and targeted molecular approaches.Objective:We aimed to demonstrate the clinical utility of Next-generation Sequencing (NGS) in pathogen identification; NGS is a maturing technology enabling the detection of miniscule amounts of cell-free microbial DNA from the bloodstream.Methods:We utilized a novel Next-generation Sequencing (NGS) test on plasma samples to diagnose a series of HIV-associated OIs that were diagnostically confirmed through conventional microbial testing.Results:In all cases, NGS test results were available sooner than conventional testing. This is the first case series demonstrating the utility of whole-genome NGS testing to identify OIs from plasma in HIV/AIDS patients.Conclusion:NGS approaches present a clinically-actionable, comprehensive means of diagnosing OIs and other systemic infections while avoiding the labor, expense, and delays of multiple tests and invasive procedures.
KEPUASAN PELAYANAN PUBLIK DI KECAMATAN KEDUNGKANDANG KOTA MALANG
Authors: Rosmitha Aisyah Anggita 
Published: February 2019

The research purpose is to find out about people satisfaction level to public service at Kedungkandang sub-district Malang city. Analysis technique used in this research is tabulation analysis and public satisfaction Index or analysis of all research data result. For the ten indicators in tabulation equation analysis, there found nine indicator stated that public satisfaction is quite enough, while one indicator stated that public satisfaction of public service is very satisfied. While for public satisfaction Index analysis, there found overall index value found index number 66.12, so that public satisfaction in Kedungkandang sub-district viewed from all indicators in public service stated quite satisfied but close to satisfaction index less satisfied because of convection result of public satisfaction Index value.
ANALISIS TINGKAT PERMINTAAN PEMBIAYAAN PADA BANK UMUM SYARIAH DI INDONESIA PERIODE 2006 – 2010
Authors: Firdausiyah Dewi Jannatul 
Published: February 2019

This study was a descriptive quantitative type of research which was conducted at 5 Islamic banks in Indonesia, entitled " The Level of Demand for financing Analysis at Islamic Banks in Indonesia Period 2006-2010”. From the results were obtained the coefficient of determination (R2) for panel data of regression model Random effect of 0.89. This means that the independent variables together were able to explain that 89% were variation in dependent variable, namely the financing demand. From the data analysis which had conducted simultaneously showed that the variable of income per capita and the profit sharing ratio had a more significant outcome of the financing demand than the variable of lending rates for working capital. It could be seen from the probability or significance level, which was variable of income per capita, profit sharing ratio, and lending rates for working capital 0.0695: 0.0612 and 0.9438. Moreover, It could be seen from the F test, which F count > F table for 59.2 > 3.49.
Occurrence of Diabetic Nephropathy After Renal Transplantation Despite Intensive Glycemic Control: An Observational Cohort Study
Authors: Coemans Maarten , Van Loon Elisabet , Lerut Evelyne , Gillard Pieter , Sprangers Ben , Senev Aleksandar , Emonds Marie-Paule , Van Keer Jan , Callemeyn Jasper , Daniëls Liesbeth , Sichien Jeroen , Verbeke Geert , Kuypers Dirk , Mathieu Chantal , Naesens Maarten 
Published: February 2019

OBJECTIVE
The kinetics and risk factors of diabetic nephropathy after kidney transplantation remain unclear. This study investigated the posttransplant occurrence of diabetic nephropathy and the contribution of posttransplant glycemic control.

RESEARCH DESIGN AND METHODS
We performed a single-center prospective cohort study of 953 renal allograft recipients and 3,458 protocol-specified renal allograft biopsy specimens up to 5 years after transplantation. The effects of pretransplant diabetes and glycemic control (glycated hemoglobin levels) on the posttransplant histology were studied.

RESULTS
Before transplantation, diabetes was present in 164 (17.2%) renal allograft recipients, primarily type 2 (n = 146 [89.0%]). Despite intensive glycemic control (glycated hemoglobin 7.00 ± 1.34% [53 ± 14.6 mmol/mol], 6.90 ± 1.22% [52 ± 13.3 mmol/mol], and 7.10 ± 1.13% [54 ± 12.4 mmol/mol], at 1, 2, and 5 years after transplantation), mesangial matrix expansion reached a cumulative incidence of 47.7% by 5 years in the pretransplant diabetes group versus 27.1% in patients without diabetes, corresponding to a hazard ratio of 1.55 (95% CI 1.07–2.26; P = 0.005). Mesangial matrix expansion was not specific for diabetic nephropathy and associated independently with increasing age. Pretransplant diabetes was associated with posttransplant proteinuria but not with estimated glomerular filtration rate, graft failure, or any other structural changes of the glomerular, vascular, or tubulointerstitial renal compartments. The occurrence of diabetic nephropathy was independent of posttransplant glycated hemoglobin levels.

CONCLUSIONS
Mesangial matrix expansion, an early indicator of diabetic nephropathy, can occur rapidly in patients with diabetes before transplantation, despite intensive glycemic control. Prevention of diabetic nephropathy requires more than pursuing low levels of glycated hemoglobin.
Synthesis, Characterization and Biological Activity of NitrogenOxygen-Sulfur (NOS) Transition Metal Complexes Derived from Novel S-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin
Authors: Abdul Manan Mohd Abdul Fatah , Bahron Hadariah , Kassim Karimah , Muhamad Mohd Asrul Hafiz , Sayed Mohamad Syed Nazmi 
Published: February 2019

A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4- dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base have been prepared and characterized using elemental analysis and various physico-chemical techniques. In the cobalt(ll) and nickel(II) complexes the SchifJbase behaves as a uninegatively charged tridentate nitrogen-oxygen-sulfur (NOS) chelating ligand, bonding through the azomethine nitrogen, thiolate sulfur and carbonylic oxygen of the isatin moiety. However. in the copper(ll), zinc(II) and cadmium(II) complexes the Schiff base behaves as a nitrogen-sulfur (NS) bidentate chelating ligand, bonding through the azomethine nitrogen and thiolate sulfur. The Schiff base and the metal complexes were evaluated with respect to antimicrobial activity, which was performed in reallion to two selected pathogenic microbials (Bacillus subtilis and Pseudomonas aeruginosa). It was observed that only the zinc Schiffbase complex exhibited strong activity against the Bacillus subtilis bacteria with an inhibition zone of25 mm.
Hybrid Approach to Treatment Tailoring for Low Back Pain: A Proposed Model of Care
Authors: Hodges Paul W. 
Published: February 2019

Synopsis Various approaches have been used to guide the treatment of low back pain. These approaches have been considered in isolation and often tested against each other. An alternative view is that a model of care that involves a hybrid approach may benefit patients with low back pain. This commentary considers the potential benefits of a sequentially applied hybrid approach for treatment tailoring to optimize resource allocation to those most likely to require comprehensive care, and then decision making toward treatment paths with the greatest potential for success. In a first step, a prognosis-based approach, such as the Subgroups for Targeted Treatment Back Screening Tool (STarT Back), identifies individuals likely to require greater resource allocation. Although a clear path is indicated toward simple and psychologically informed care for the low- and high-risk groups, respectively, there is limited guidance for the large medium-risk group. For that group, the hybrid model provides a stepwise path of additional methods to guide treatment selection. This includes subgrouping based on pain mechanism to guide priority domains for the next phase, which includes tailoring of psychological and movement-based approaches. Motor control approaches to exercise would be indicated for individuals with medium risk and a nociceptive pain mechanism, with treatment guided by detailed assessment via one of several paradigms. Psychologically informed treatments are tailored to those with medium risk and a predominantly central pain mechanism, guided by detailed assessment of psychosocial features. A hybrid approach to a model of care could simplify treatment selection and take advantage of the benefits of each method in a time- and cost-efficient manner. J Orthop Sports Phys Ther 2019;49(6):453–463. Epub 13 Feb 2019. doi:10.2519/jospt.2019.8774
Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015
Authors: Barkoff Alex-Mikael , Mertsola Jussi , Pierard Denis , Dalby Tine , Hoegh Silje Vermedal , Guillot Sophie , Stefanelli Paola , van Gent Marjolein , Berbers Guy , Vestrheim Didrik , Greve-Isdahl Margrethe , Wehlin Lena , Ljungman Margaretha , Fry Norman K. , Markey Kevin , He Qiushui 
Published: February 2019

Introduction
Pertussis outbreaks have occurred in several industrialised countries using acellular pertussis vaccines (ACVs) since the 1990s. High prevalence of pertactin (PRN)-deficient Bordetella pertussis isolates has been found in these countries.

Aims
To evaluate in Europe: (i) whether proportions of PRN-deficient strains increased in consecutive collections of B. pertussis clinical isolates; (ii) if the frequency of PRN-deficient strains in countries correlated with the time since ACV introduction; (iii) the presence of pertussis toxin (PT)-, filamentous haemagglutinin (FHA)- or fimbriae (Fim)-deficient isolates.

Methods

B. pertussis clinical isolates were obtained from different European countries during four periods (EUpert I–IV studies): 1998 to 2001 (n = 102), 2004 to 2005 (n = 154), 2007 to 2009 (n = 140) and 2012 to 2015 (n = 265). The isolates’ selection criteria remained unchanged in all periods. PRN, PT, FHA and Fim2 and Fim3 expression were assessed by ELISA.

Results
In each period 1.0% (1/102), 1.9% (3/154), 6.4% (9/140) and 24.9% (66/265) of isolates were PRN-deficient. In EUpert IV, PRN-deficient isolates occurred in all countries sampled and in six countries their frequency was higher than in EUpert III (for Sweden and the United Kingdom, p < 0.0001 and p = 0.0155, respectively). Sweden and Italy which used ACVs since the mid 1990s had the highest frequencies (69%; 20/29 and 55%; 11/20, respectively) while Finland, where primary immunisations with ACV containing PRN dated from 2009 had the lowest (3.6%). Throughout the study, no PT- or FHA-deficient isolate and one Fim2/3-deficient was detected.

Conclusion
Results suggest that the longer the period since the introduction of ACVs containing PRN, the higher the frequency of circulating PRN-deficient isolates.
EARLY OUTCOMES IN PATIENTS WITH SUSPECTED ACUTE CORONARY SYNDROME WITHOUT PERSISTENT ST ELEVATION, TRANSPORTED TO A VASCULAR CENTER BY AMBULANCE
Authors: Kharitonov A. A. , Shtegman O. A. 
Published: February 2019

The aimwas to study early outcomes in patients with suspected acute coronary syndrome without ST elevation who were transported by emergency to the vascular center.Material and Methods. We studied medical records from 396 patients with suspected acute coronary syndrome without ST elevation. A telephone survey of patients or their relatives was conducted within two months after the emergency call.Results. In-hospital diagnosis of acute coronary syndrome was confirmed only in 30.6% of patients with suspected acute coronary syndrome without ST elevation admitted to the vascular center. Cardiologists in the vascular center were ruling out diagnosis of acute coronary syndrome without ST elevation based on data of clinical examination and electrocardiography. During the following two months, 6.4% of the patients with ruled out diagnosis of acute coronary syndrome called emergency again; 2% of the patients were admitted with acute coronary syndrome to the vascular center; and 2.4% of the patients died at home.Conclusion. In real clinical practice, the assessment of myocardial necrosis biomarkers has been used not enough in cases of suspected acute coronary syndrome without ST elevation.
ANALYSIS OF DATA FROM MINOCA PATIENTS BASED ON COMPARISON OF TOTAL REGISTER OF ACUTE CORONARY SYNDROME IN THE KRASNODAR REGION WITH FOREIGN REGISTERS
Authors: Kruchinova S. V. , Kosmacheva E. D. , Raff S. A. , Porkhanov V. A. 
Published: February 2019

The review presents a comparative analysis of data from patients with myocardial infarction with non-obstructive coronary arteries. Data were obtained from the total register of acute coronary syndrome in the Krasnodar Krai and were compared with data of foreign registers.
C677T POLYMORPHISM IN THE METHYLENETETRAHYDROFOLATE REDUCTASE GENE IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION
Authors: Mitkovskaya N. P. , Balysh E. M. , Gusina A. A. , Statkevich T. V. 
Published: February 2019

The aimof the study was to identify clinical and laboratory features of the disease in patients with myocardial infarction with ST-segment elevation and C677T polymorphism in the methylenetetrahydrofolate reductase gene.Material and Methods. A total of 81 patients with ST-segment elevation myocardial infarction were examined. Clinical, laboratory, instrumental, and statistical methods were used.Conclusion. Among patients with ST-segment elevation myocardial infarction, the proportion of persons with homozygous carriership of polymorphic alleles in the MTHFR gene was 30% (genotype 677СС); and 58.02% (genotype 677СT) of patients were heterozygous carriers. Patients with homozygous carriership of polymorphic alleles in the MTHFR gene were characterized by higher values of Big endothelin-1 and homocysteine in serum compared with persons with genotype 677СС: 10.7 (4.5–14.5) pg/mL, 27 (20–28) μmol/L, and 2.7 (2.2–3.8) pg/mL, and 17 (14–20) μmol/L, respectively, p<0.05. A positive moderate force correlation was found between the carriership of polymorphic alleles MTHFR C677T and homocysteine levels (r=0.42, p<0.05) and Big endothelin-1 (r=0.45, p<0.05) in the cohort under study. In patients with homozygous carriership of polymorphic alleles in the MTHFR gene, myocardial infarction was significantly more often complicated by the development of recurrent coronary events in comparison with groups with heterozygous carriership and the absence of polymorphic alleles in this gene: 88.9% (n=8) versus 42.55% (n=20), χ2=6.5, p<0.05 and 28% (n=7), χ2=10.0, p<0.01 respectively.
UV-B ışın uygulamalarının domates, hıyar ve patlıcan fidelerinde fide gelişimi ve kalitesi üzerine etkileri
Authors: CANBAY Serkan , POLAT Ersin 
Published: February 2019

Bu çalışmada, UV-B ışın
uygulamalarının domates, hıyar ve patlıcan fidelerinde fide gelişimi ve
kalitesi üzerine etkileri araştırılmıştır. Bu amaçla domates (Solanum lycopersicum L. cv. Alsancak-RN F1), hıyar (Cucumis sativus L. cv. Çakır F1) ve
patlıcan (Solanum melongena L.
cv. Anamur F1) fideleri kontrol (0 kJ m-2 gün-1), 10.8 kJ m-2 gün-1 (düşük doz) ve 16.2 kJ m-2 gün-1
(yüksek doz) UV-B ışın uygulamasına ilk gerçek yapraklı oldukları dönemden
itibaren 10 gün (sırasıyla 76.5 dk gün-1 ve 114.75 dk gün-1)
süre ile tabi tutulmuşlardır. Araştırmada fide boyu, yaprak sayısı, kök
boğazı çapı, kök uzunluğu, kök ve üst aksam yaş ve kuru ağırlıkları, yaprak
alanı, yaprakta klorofil miktarı ve yaprak rengi belirlenmiştir. Domates fide yapraklarındaki klorofil miktarı, düşük
doz UV-B ışın uygulamasında artarken yüksek doz UV-B uygulamasında azalmıştır.
Yüksek doz UV-B ışın uygulamasının, fide köklerinde kuru madde miktarını artırdığı
belirlenmiştir. Hıyar fide yapraklarındaki klorofil miktarı, düşük doz UV-B
uygulamasında artmıştır. Fidelerde yaprak sayısı ve yaprak alanı, düşük doz
UV-B uygulamasında artarken, yüksek doz UV-B uygulamasında ise azalmıştır. Kök
boğazı çapı, kök uzunluğu ve üst aksamdaki kuru madde miktarının yüksek doz
UV-B uygulamasında azaldığı saptanmıştır. Düşük doz UV-B uygulanan patlıcan
fidelerinde yaprak rengi Chroma (C*) değerinin
azaldığı tespit edilmiştir. UV-B uygulamalarının patlıcan fidelerinde yaprak
rengi L* değeri, kök boğazı çapı ve
yaprak alanını azaltıcı etki yaptığı belirlenmiştir. UV-B ışın uygulamalarının
türe ve doz miktarına bağlı olarak fidelerin gelişimi ve morfolojik yapısı
üzerine etki ettiği belirlenmiştir.
EKPLORASI DAN PENANGKARAN BIBIT RUMPUT LAUT (Eucheuma cottonii) DI PERAIRAN TELUK EKAS LOMBOK TIMUR
Authors: Cokrowati Nunik , Diniarti Nanda , Setyowati Dewi NurÃ¢â¬â¢aeni , Waspodo Saptono , Marzuki M. 
Published: February 2019

Abstrak: Tujuan dari penelitian ini adalah untuk mendapatkan bibit Eucheuma cottonii dari habitat aslinya di perairan Teluk Ekas dan menangkarkan bibit tersebut. Penelitian ini dilakukan di Teluk Ekas Lombok Timur Nusa Tenggara Barat. Metode yang digunakan pada penelitian ini adalah metode ekplorasi di perairan Teluk Ekas serta mendeskripsikan hasil pengamatan. Eucheuma cottonii yang berhasil di temukan dan di ekslporasi dari perairan Teluk Ekas, memiliki ciri morfologi lebih banyak memiliki bakal talus sehingga tampak sebagai duri-duri pada thalus. Talus keras dan kaku serta berwarna coklat kehijauan. Eucheuma cottoniidijumpai menempel pada batuan dan karang yang berada pada kisaran kedalaman 1 meter sampai dengan 1,5 meter. Eucheuma cottoniimenempel kuat pada subtrat sehingga sulit untuk diambil dengan tangan, harus menggunakan pisau atau alat pemotong lainnya. Eucheuma cottoniidapat ditangkarkan dan tumbuh dengan baik di perairan Teluk Ekas.ÃÂ ÃÂ Kata kunci: Kappaphycus alvarezii, habitat, talus, karang, domestikasi ÃÂ Abstract: The objective of this study was to obtain Eucheuma cottonii seeds from their natural habitat in Ekas Bay and breed these seeds. This research was conducted in Ekas Bay, Lombok Timur, Nusa Tenggara Barat. The method used in this study is the exploration method and description method. Eucheuma cottonii which has been found, has more morphological characteristics that have a talus so that it appears as thorns in the thalus. Talus is hard and stiff and has a greenish brown color. Eucheuma cottonii was found attached to rocks and corals which were in the range of 1 meter to 1.5 meters. Eucheuma cottonii sticks firmly to the substrate so that it is difficult to take by hand, must use a knife or other cutting tool. Eucheuma cottonii can be bred and grow well in Ekas Bay.ÃÂ Keywords : Kappaphycus alvarezii, habitat, talus, coral, domestication
Analisis Strategi Promosi Dalam Pengembangan Pariwisata Di Kabupaten Lebak Banten
Authors: Adiyanto Yoga , Supriatna Yuda 
Published: February 2019

Kabupaten Lebak yang beribukota Rangkasbitung merupakan salah satu Kabupaten di Provinsi Banten yang menjadi kawasan pengembangan pariwisata karena memiliki banyak potensi pariwisata yang menarik.Diantaranya : Pantai Bagedur,Pantai Sawarna,Pantai Bayah,Pantai Cikotok,Suku Baduy luar dan Baduy Dalam,dan lain sebgainya. Sektor pariwisata di Kabupaten Lebak Banten, merupakan sektor yang diunggulkan dan berkontribusi terhadap PDRB (Pendapatan Daerah Regional Bruto) Kabupaten Lebak Banten setiap tahunnya. Hal ini disebabkan oleh banyaknya Objek Daya Tarik Wisata (ODTW) pesonan keindahan alam yang berpadu dengan keragaman budaya, kesenian, sejarah maupun kuliner yang ada dan tersebar di beberapakecamatan di Kabupaten Lebak.Penelitian ini bertujuan 1. Untuk mengetahui dampak strategi promosi dalam Meningkatkan kunjungan wisatawan; 2. Untuk mengetahui strategi promosi yang paling efektif dalam meningkatkan kunjungan wisatawan pada pariwisata Kabupaten Lebak Banten. Untuk menyelesaikan penelitian ini peneliti menggunakan metode deskriptif kualitatif. Pengumpulan data dilakukan dengan wawancara, observasi langsung, dan dokumentasi. Analisis data dilakukan melalui pengumpulan data, reduksi data, sajian data dan penarikan kesimpulan. Pemeriksaan keabsahan data dilakukan dengan triangulasi data. Hasil dari penelitian ini menunjukan 1. Promosi yang dilakukan oleh Dinas Pariwisata dan Ekonomi Kreatif adalah ikut dalam kegiatan festival, pameran, memasang iklan melalui beberapa media, dan mengadakan event pariwisata. Promosi melalui media cetak seperti brosur, pamflet, dan media elektronik sebagai sarana promosi tidak memberikan dampak yang signifikan dalam meningkatkan kunjungan wisatawan karena kecenderungan masyarakat saat ini yang lebih banyak mengakses internet dibandingkan media konvensional 2. Event kepariwisataan yang dilakukan oleh Dinas Pariwisata dan Ekonomi Kreatif Kabupaten Lebak Banten merupakan promosi yang paling efektif dalam meningkatkan kunjungan wisatawan karena dalam setiap event yang diselenggarakan, Dinas Pariwisata dan Ekonomi Kreatif Kabupaten Lebak Banten memiliki target untuk mendatangkan pengunjung dalam jumlah besar. Selain itu, tour agent dan freelance blogger berperan aktif mempromosikan pariwisata melalui internet dan media sosial dan juga wisatawan menjadi agen promosi by mouth promotion.Kata kunci : Strategi,Promosi,Pengembangan,Pariwisata