bluuebunny/crossref_metadata_2025_split huggingface dataset:
Drastische Verlangsamung der magnetischen Relaxation durch starke Austauschkopplungen in einem luftstabilen, radikalverbrückten Cobalt(II)‐Einzelmolekülmagneten
Authors: Albold Uta , Bamberger Heiko , Hallmen Philipp P. , van Slageren Joris , Sarkar Biprajit 
Published: May 2019

AbstractDie zur magnetischen Bistabilität führende Energiebarriere wird in molekularen Clustern durch die magnetische Anisotropie der einzelnen Komponenten des Clusters bestimmt. Die Verwendung eines anisotropen, vierfach koordinierten Cobalt(II)‐Bausteines ermöglichte die Darstellung eines luft‐ und hydrolysestabilen, stark gekoppelten Drei‐Spin‐Systems. Dieses konnte den Raman‐Relaxationsprozess erheblich unterdrücken, wodurch die Relaxation der Magnetisierung gegenüber der des verwendeten Bausteins um ein 350‐faches verlängert wurde, mit dem gleichzeitigen Auftreten einer ausgeprägten Hysterese. Bei niedrigen Temperaturen konnte somit eine Relaxationszeit von bis zu 9 Stunden beobachtet werden.
Direct Visualization of Pyrrole Reactivity upon Confinement within a Cyclodextrin Metal–Organic Framework
Authors: Nuñez‐Lopez Alejandro , Galbiati Marta , Padial Natalia M. , Ganivet Carolina R. , Tatay Sergio , Pardo Emilio , Armentano Donatella , Martí‐Gastaldo Carlos 
Published: May 2019

AbstractMetal–organic frameworks can be used as porous templates to exert control over polymerization reactions. Shown here are the possibilities offered by these crystalline, porous nanoreactors to capture highly‐reactive intermediates for a better understanding of the mechanism of polymerization reactions. By using a cyclodextrin framework the polymerization of pyrrole is restricted, capturing the formation of terpyrrole cationic intermediates. Single‐crystal X‐ray diffraction is used to provide definite information on the supramolecular interactions that induce the formation and stabilization of a conductive array of cationic complexes.
A Yolk–Shell Structured Silicon Anode with Superior Conductivity and High Tap Density for Full Lithium‐Ion Batteries
Authors: Zhang Lei , Wang Chengrui , Dou Yuhai , Cheng Ningyan , Cui Dandan , Du Yi , Liu Porun , Al‐Mamun Mohammad , Zhang Shanqing , Zhao Huijun 
Published: May 2019

AbstractThe poor cycling stability resulting from the large volume expansion caused by lithiation is a critical issue for Si‐based anodes. Herein, we report for the first time of a new yolk–shell structured high tap density composite made of a carbon‐coated rigid SiO2 outer shell to confine multiple Si NPs (yolks) and carbon nanotubes (CNTs) with embedded Fe2O3 nanoparticles (NPs). The high tap density achieved and superior conductivity can be attributed to the efficiently utilised inner void containing multiple Si yolks, Fe2O3 NPs, and CNTs Li+ storage materials, and the bridged spaces between the inner Si yolks and outer shell through a conductive CNTs “highway”. Half cells can achieve a high area capacity of 3.6 mAh cm−2 and 95 % reversible capacity retention after 450 cycles. The full cell constructed using a Li‐rich Li2V2O5 cathode can achieve a high reversible capacity of 260 mAh g−1 after 300 cycles.
Staged Surface Patterning and Self‐Assembly of Nanoparticles Functionalized with End‐Grafted Block Copolymer Ligands
Authors: Rossner Christian , Zhulina Ekaterina B. , Kumacheva Eugenia 
Published: May 2019

AbstractUsing two orthogonal external stimuli, programmable staged surface patterning and self‐assembly of inorganic nanoparticles (NPs) was achieved. For gold NPs capped with end‐grafted poly(styrene‐block‐(4‐vinylbenzoic acid)), P(St‐block‐4VBA), block copolymer ligands, surface‐pinned micelles (patches) formed from NP‐adjacent PSt blocks under reduced solvency conditions (Stimulus 1); solvated NP‐remote P(4VBA) blocks stabilized the NPs against aggregation. Subsequent self‐assembly of patchy NPs was triggered by crosslinking the P(4VBA) blocks with copper(II) ions (Stimulus 2). Block copolymer ligand design has a strong effect on NP self‐assembly. Small, well‐defined clusters assembled from NPs functionalized with ligands with a short P(4VBA) block, while NPs tethered with ligands with a long P(4VBA) block formed large irregularly shaped assemblies. This approach is promising for high‐yield fabrication of colloidal molecules and their assemblies with structural and functional complexity.
Self‐healing polyurethane based on a difuranic monomer from biorenewable source
Authors: Platonova Elena O. , Vlasov Evgeny , Pavlov Alexander A. , Kireynov Alexey , Nelyub Vladimir A. , Polezhaev Alexander V. 
Published: May 2019

ABSTRACTNew monomer difurfurylamine easily obtainable from furfural (inexpensive biorenewable feedstock) was used for the synthesis of the polyurethane preform. The latest was cross‐linked with different amount of BMI (bismaleimide) via Diels–Alder reaction, and polymers with a high and low degree of cross‐linking were obtained and characterized. The self‐healing efficiency was investigated with differential scanning calorimetry, scanning electronic microscopy, X‐ray tomography, and tensile strength measurement end up to 95% restoration of mechanical properties was demonstrated for one composition after thermal treatment. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2019,136, 47869.
Role of serine protease inhibitors in insect‐host‐pathogen interactions
Authors: Shakeel Muhammad , Xu Xiaoxia , De Mandal Surajit , Jin Fengliang 
Published: May 2019

AbstractSerine protease inhibitors (serpins), evolutionary old, structurally conserved molecules, are a superfamily of proteins found in almost all living organisms. Serpins are relatively large, typically 350–500 amino acids in length, with three β‐sheets and seven to nine α‐helices folding into a conserved tertiary structure with a reactive center loop. Serpins perform various physiological functions in insects, including development, digestion, host‐pathogen interactions, and innate immune response. In insects, the innate immune system is characterized as the first and major defense system against the invasion of microorganisms. Serine protease cascades play a critical role in the initiation of innate immune responses, such as melanization and the production of antimicrobial peptides, and are strictly and precisely regulated by serpins. Herein, we provide a microreview on the role of serpins in the insect‐host‐pathogen interactions, emphasizing their role in immune responses, particularly in diamondback moth (Plutella xylostella), highlighting the important discoveries and also the gaps that remain to be explored in future studies.
Transition‐Metal‐Mediated Cleavage of C−C Bonds in Aromatic Rings
Authors: Jakoobi Martin , Sergeev Alexey G. 
Published: May 2019

AbstractMetal‐mediated cleavage of aromatic C−C bonds has a range of potential synthetic applications: from direct coal liquefaction to synthesis of natural products. However, in contrast to the activation of aromatic C−H bonds, which has already been widely studied and exploited in diverse set of functionalization reactions, cleavage of aromatic C−C bonds remainsTerra incognita. This Minireview summarizes the recent progress in this field and outlines key challenges to be overcome to develop synthetic methods based on this fundamental organometallic transformation.
Global projective lag synchronization of fractional order memristor based BAM neural networks with mixed time varying delays
Authors: Pratap Anbalagan , Raja Ramachandran , Sowmiya Chandran , Bagdasar Ovidiu , Cao Jinde , Rajchakit Grienggrai 
Published: May 2019

AbstractThis paper addresses Master–Slave synchronization for some memristor‐based fractional‐order BAM neural networks (MFBNNs) with mixed time varying delays and switching jumps mismatch. Firstly, considering the inherent characteristic of FMNNs, a new type of fractional‐order differential inequality is proposed. Secondly, an adaptive switching control scheme is designed to realize the global projective lag synchronization goal of MFBNNs in the sense of Riemann‐Liouville derivative. Then, based on a suitable Lyapunov method, under the framework of set‐valued map, differential inclusions theory, fractional Barbalat's lemma and proposed control scheme, some new projective lag synchronization criteria for such MFBNNs are obtained. Finally, some numerical examples are presented to illustrate the effectiveness of the proposed theoretical analysis.
Oil palm cultivation and production in South America: status and perspectives
Authors: Medina Jesus David Coral , Magalhães Antonio Irineudo , Zamora Hernan Dario , Melo Jaime Dario Quijano 
Published: May 2019

AbstractSouth America is responsible for 16% of the world's agricultural production and 21% of the world's livestock. Palm harvesting has been gaining special attention, with constant growth in Brazil, Colombia, and Ecuador. Fast expansion in palm plantations in the equatorial zone around the world has been motivated by an increase in farming of species such as
Elaeis guineensis, Elaeis oleifera
, and Elaeis odora. Parallel to the increase of oil‐palm harvesting, the generation of residues is an important aspect to take into consideration. This work presents an overview of palm cultivation in South America, focusing on the full use of the fruits of the palm for biodiesel production. It also discusses the status of the main projects in South America for second‐generation biofuels production from governmental agencies and private institutes. From the data consulted it was determined that Colombia, Ecuador, and Brazil have policies and incentives for the agrobusiness of oil‐palm production. © 2019 Society of Chemical Industry and John Wiley & Sons, Ltd
Prognostic factors for overall survival in patients with chronic myeloid leukemia treated with imatinib at the National Cancer Institute – Mexico, from 2000 to 2016
Authors: Ylescas‐Soria Jimena , de la Torre‐Lujan Alfredo H. , Herrera Luis A. , Miranda Daniela , Grimaldo Flavio , Rivas Silvia , Cervera Eduardo , Meneses‐García Abelardo , Leon-Sarmiento Fidias E. , Prada Diddier 
Published: May 2019

AbstractTo determine potential predictors of long‐term survival in a large set of Hispanic (Mexican) patients with chronic myeloid leukemia (CML) treated with imatinib. We conducted an analysis with data from 411 patients with CML treated at the National Cancer Institute – Mexico, between January 2000 and December 2016. We found a median age at diagnosis of 40 years (range: 18‐84 years). The survival rate at 150 months was 82.02%, and we found that phase at diagnosis (β: 0.447, 95% Confidence Interval [95% CI]: 0.088, 0.806; P = 0.015), prognostic scales (Sokal [P = 0.021] and Hasford [β: 0.369, 95% CI: 0.049, 0.688; P = 0.024]) and hematological response at 3 months (β: 0.717, 95% CI: 0.443, 0.991; P < 0.001), but not molecular response (P = 0.834 for 6 months, P = 0.927 for 12 months, P = 0.250 for 18 months), were independently associated with overall survival. Survival analysis in subsets, according to the initial phase (chronic, accelerated and blastic phase) did not show any effect according to prognostic scales (P > 0.05). Mexican patients with CML have repeatedly been diagnosed at earlier ages. Prognostic factors in CML may differ according to the ethnic or geographical context. We found that phase at diagnosis, prognostic scale and hematological response at 3 months were independent predictors of survival.
Synthesis andin VitroAntimicrobial Activity Screening of New 3‐Acetyl‐2,5‐disubstituted‐1,3,4‐oxadiazoline Derivatives
Authors: Popiołek Łukasz , Biernasiuk Anna , Paruch Kinga , Malm Anna , Wujec Monika 
Published: May 2019

AbstractThirteen new 3‐acetyl‐2,5‐disubstituted‐1,3,4‐oxadiazoline derivatives were synthesized from corresponding hydrazide‐hydrazones of isonicotinic acid in the reaction with acetic anhydride. The obtained compounds were identified with the use of spectral methods (IR,1H‐NMR,13C‐NMR, MS).In vitroantimicrobial activity screening of synthesized compounds against a panel of bacteria and fungi revealed interesting antibacterial and antifungal activity of tested 1,3,4‐oxadiazoline derivatives, which is comparable to that of commonly used antimicrobial agents.
WDR13 promotes the differentiation of bovine skeletal muscle‐derived satellite cells by affecting PI3K/AKT signaling
Authors: Fu Yuying , Li Shuang , Tong Huili , Li Shufeng , Yan Yunqin 
Published: May 2019

AbstractMuscle satellite cells are usually at rest, and when externally stimulated or regulated, they can be further differentiated by cell fusion to form new myotubes and muscle fibers. WD repeat domain 13 (WDR13) is highly conserved in vertebrates. Studies have shown that mice lacking the Wdr13 gene develop mild obesity, hyperinsulinemia, and increased islet β cell proliferation. However, the role of WDR13 in bovine cells is unclear. Here, we investigated the effect of WDR13 on bovine skeletal muscle‐derived satellite cells (MDSCs). We found that WDR13 was upregulated in bovine MDSCs using western blotting and immunofluorescence experiments. Moreover, activation and inhibition of WDR13 expression increased and decreased cell differentiation, respectively, suggesting that WDR13 promotes bovine MDSC differentiation. To further understand the mechanism of action of WDR13, we examined changes in the PI3K/AKT signaling pathway following WDR13 activation or inhibition. In addition, cells were treated with a phosphoinositide kinase 3 (PI3K) inhibitor, LY294004, to observe cell differentiation. The results showed that activation of WDR13 inhibited the PI3K/AKT signaling pathway and enhanced cell differentiation. These data suggest that WDR13 can promote the differentiation of bovine MDSCs by affecting the PI3K/AKT signaling pathway.
Photoinduced Nonlinear Contraction Behavior in Metal–Organic Frameworks
Authors: Shi Yi‐Xiang , Chen Huan‐Huan , Zhang Wen‐Hua , Day Gregory S. , Lang Jian‐Ping , Zhou Hong‐Cai 
Published: May 2019

AbstractThe photoinduced dynamic behavior of flexible materials has received considerable attention for potential applications, such as in data storage or as smart optical devices and molecular mechanical actuators. Until now, precisely controlling expansion and contraction with light has remained a challenge. Unraveling the detailed mechanisms of photoinduced structural transformations remains a critical step necessary to understand the molecular architecture necessary for the design of sensitive photomechanical actuators. Herein, a two‐dimensional flexible metal–organic framework [Zn2(bdc)2(3‐CH3‐spy)2]⋅H2O (Zn2‐1; H2bdc=1,4‐benzenedicaboxylic acid; 3‐CH3‐spy=3‐methylstyrylpyridine) with a positive volumetric thermal expansion coefficient of +78.78×10−6 K−1 is reported. Upon light irradiation at different wavelengths, the MOF underwent a [2+2] cycloaddition, which afforded a family of isomeric, three‐dimensional MOFs (Zn2‐2 n, n=a–d) in a single‐crystal‐to‐single‐crystal (SCSC) manner. An unprecedented phenomenon, that is, photoinduced nonlinear contraction (PINC), was observed during this conversion. The PINC is caused by conformational changes in the 3‐CH3‐spy and bdc2− ligands, the bending of metal–ligand bonds, and the local distortion of the paddle‐wheel SBUs. The formation of a “wrinkle morphology” on the crystal surface after the photoreaction was observed by AFM. This PINC behavior can broaden the studies on materials expansion and offer a photodriven approach for the future design of supersensitive photomechanical actuators.
A New Class of Lanthanide Complexes with Three Ligand Centered Radicals: NMR Evaluation of Ligand Field Energy Splitting and Magnetic Coupling
Authors: Hiller Markus , Sittel Thomas , Wadepohl Hubert , Enders Markus 
Published: May 2019

AbstractCombination of three radical anionic Ph‐BIAN ligands (Ph‐BIAN=bis‐(phenylimino)‐acenaphthenequinone) with lanthanoid ions leads to a series of homoleptic, six‐coordinate complexes of the type Ln(Ph‐BIAN)3. Magnetic coupling data were measured by paramagnetic solution NMR spectroscopy. Combining 1H NMR with 2H NMR of partially deuterated compounds allowed a detailed study of the magnetic susceptibility anisotropies over a large temperature range. The observed chemical shifts were separated into ligand‐ and metal‐centered contributions by comparison with the Y analogue (diamagnetic at the metal). The metal‐centered contributions of the complexes with the paramagnetic ions could then be separated into pseudocontact and Fermi contact shifts. The latter is large within the Ph‐BIAN scaffold, which shows that magnetic coupling is significant between the lanthanide ion and the radical ligand. Pseudocontact shifts were further correlated to structural data obtained from X‐ray diffraction experiments. Ligand‐field parameters were determined by fitting the temperature dependence of the observed magnetic susceptibility anisotropies. The electronic structure determined by this approach shows, that the Er and Tm analogues are candidates for single molecule magnets (SMM). These results demonstrate the possibilities for the application of NMR spectroscopy in investigations of paramagnetic systems in general and single molecule magnets in particular.
Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using Pd0‐CalB CLEA as a Biohybrid Catalyst
Authors: Gustafson Karl P. J. , Görbe Tamás , de Gonzalo‐Calvo Gonzalo , Yuan Ning , Schreiber Cynthia L. , Shchukarev Andrey , Tai Cheuk‐Wai , Persson Ingmar , Zou Xiaodong , Bäckvall Jan‐E. 
Published: May 2019

AbstractHerein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross‐linked enzyme aggregates of lipase B of Candida antarctica (CalB CLEA) for the dynamic kinetic resolution (DKR) of benzylic amines. A set of amines were demonstrated to undergo an efficient DKR and the recyclability of the catalysts was studied. Extensive efforts to further elucidate the structure of the catalyst are presented.
Advanced stage at diagnosis and elevated mortality among US patients with cancer infected with HIV in the National Cancer Data Base
Authors: Coghill Anna E. , Han Xuesong , Suneja Gita , Lin Chun Chieh , Jemal Ahmedin , Shiels Meredith S. 
Published: May 2019

BackgroundPeople living with HIV (PLWH) are at an increased risk of developing several cancers, but to the authors’ knowledge less is known regarding how HIV impacts the rate of progression to advanced cancer or death.MethodsThe authors compared stage of disease at the time of presentation and mortality after diagnosis between 14,453 PLWH and 6,368,126 HIV‐uninfected patients diagnosed with cancers of the oral cavity, stomach, colorectum, anus, liver, pancreas, lung, female breast, cervix, prostate, bladder, kidney, and thyroid and melanoma using data from the National Cancer Data Base (2004‐2014). Polytomous logistic regression and Cox proportional hazards regression were used to evaluate the association between HIV, cancer stage, and stage‐adjusted mortality after diagnosis, respectively. Regression models accounted for the type of health facility at which cancer treatment was administered and the type of individual health insurance.ResultsHIV‐infected patients with cancer were found to be more likely to be uninsured (HIV‐infected: 5.0% vs HIV‐uninfected: 3.3%; P < .0001) and were less likely to have private health insurance (25.4% vs 44.7%; P < .0001). Compared with those not infected with HIV, the odds of being diagnosed at an advanced stage of disease were significantly elevated in PLWH for melanoma and cancers of the oral cavity, liver, female breast, prostate, and thyroid (odds ratio for stage IV vs stage I range, 1.24‐2.06). PLWH who were diagnosed with stage I to stage III disease experienced elevated mortality after diagnosis across 13 of the 14 cancer sites evaluated, with hazard ratios ranging from 1.20 (95% CI, 1.14‐1.26) for lung cancer to 1.85 (95% CI, 1.68‐2.04), 1.85 (95% CI, 1.51‐2.27), and 2.93 (95% CI, 2.08‐4.13), respectively, for cancers of the female breast, cervix, and thyroid.ConclusionsPLWH were more likely to be diagnosed with advanced‐stage cancers and to experience elevated mortality after a cancer diagnosis, even after accounting for health care–related factors.
Application of the Milan System for Reporting Submandibular Gland Cytopathology: An international, multi‐institutional study
Authors: Maleki Zahra , Baloch Zubair , Lu Ryan , Shafique Khurram , Song Sharon J. , Viswanathan Kartik , Rao Rema A. , Lefler Holly , Fatima Aisha , Wiles Austin , Jo Vickie Y. , Wang He , Fadda Guido , Powers Celeste N. , Ali Syed Z. , Pantanowitz Liron , Siddiqui Momin T. , Nayar Ritu , Klijanienko Jerzy , Barkan Guliz A. , Krane Jeffrey F. , Rossi Esther D. , Callegari Fabiano , Kholová Ivana , Bongiovanni Massimo , Faquin William C. , Pusztaszeri Marc P. 
Published: May 2019

BackgroundThe Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) is a 6‐tier diagnostic category system with associated risks of malignancy (ROMs) and management recommendations. Submandibular gland fine‐needle aspiration (FNA) is uncommon with a higher frequency of inflammatory lesions and a higher relative proportion of malignancy, and this may affect the ROM and subsequent management. This study evaluated the application of the MSRSGC and the ROM for each diagnostic category for 734 submandibular gland FNAs.MethodsSubmandibular gland FNA cytology specimens from 15 international institutions (2013‐2017) were retrospectively assigned to an MSRSGC diagnostic category as follows: nondiagnostic, nonneoplastic, atypia of undetermined significance (AUS), benign neoplasm, salivary gland neoplasm of uncertain malignant potential (SUMP), suspicious for malignancy (SM), or malignant. A correlation with the available histopathologic follow‐up was performed, and the ROM was calculated for each MSRSGC diagnostic category.ResultsThe case cohort of 734 aspirates was reclassified according to the MSRSGC as follows: nondiagnostic, 21.4% (0%‐50%); nonneoplastic, 24.2% (9.1%‐53.6%); AUS, 6.7% (0%‐14.3%); benign neoplasm, 18.3% (0%‐52.5%); SUMP, 12% (0%‐37.7%); SM, 3.5% (0%‐12.5%); and malignant, 13.9% (2%‐31.3%). The histopathologic follow‐up was available for 333 cases (45.4%). The ROMs were as follows: nondiagnostic, 10.6%; nonneoplastic, 7.5%; AUS, 27.6%; benign neoplasm, 3.2%; SUMP, 41.9%; SM, 82.3%; and malignant, 93.6%.ConclusionsThis multi‐institutional study shows that the ROM of each MSRSGC category for submandibular gland FNA is similar to that reported for parotid gland FNA, although the reported rates for the different MSRSGC categories were variable across institutions. Thus, the MSRSGC can be reliably applied to submandibular gland FNA.
The Next Stage in Colloidal Synthesis of Aqueous CdSe Quantum Dots: High Throughput and Intense Emissive Properties
Authors: Saha Arpita , Saini Abhishek , Vinas Clara , Teixidor Francesc 
Published: May 2019

AbstractQuantum dots (QDs) of CdSe have been produced with high yield using common reagents in water at 150 °C. The QDs thus produced are water compatible, show intense fluorescence emission and have high quantum yields (QYs). Their size can be controlled similarly to the high temperature organometallic method of synthesizing QDs, and these QDs produced in organic solvents at high temperature and the QDs produced in water both show comparable QYs. The great advantage is that a green solvent, water, is used and their separation from the water is very simple. They can be stored dry very easily. Similar to the organic method their size can be controlled by time, producing QDs with distinct fluorescence. The size obtained by TEM for 30, 60 and 90 minutes of reaction is 4.18 nm, 6.7 nm and 8.6 nm, respectively. This parallels the change in the emission wavelength of the QDs produced; green, yellow and orange, respectively. TEM dimensions are very similar to these of DLS (dynamic light scattering). These QDs display the hexagonal wurtzite phase, common for the higher temperature synthesis of QDs in organic solvents, and not the zinc blende phase of CdSe QDs common for the lower temperature water synthesis of QDs. The prepared QDs have shown the same intense emission for over a year after being synthesized.