bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of "Child Friendly ICT" Textbooks to Improve Professional Competence of Teacher Candidates : A Case Study of Early Childhood Education Program Students
Authors: SUMARNİ Sri , RAMADHANİ Rahmi , SAZAKİ Yoppy , ASTİKA Ruri Tria , ANDİKA Windi Dwi , PRASETİYO Andika Eko 
Published: September 2019

The purpose of
this study is to develop textbooks on child-friendly of Information, Communication, &amp; Technology (ICT) that are
valid, practical and effective in improving the professional competence of
teacher education students (PG) PAUD Sriwijaya University. This study uses the
Research and Development model with the type of Analysis, Design, Development, Implementation, and Evaluation (ADDIE) which
consists of five stages, namely analysis, design, develop, implementation, and
evaluation. The sample in this study was Sriwijaya University PAUD teacher
education study program students. In the implementation phase, field trials
were carried out as a result of the development of child-friendly ICT-based
teaching books with a sample of 42 people consisting of 12 samples for the
small group test and 30 samples for the large group test. The data obtained in
this study were analyzed using qualitative analysis and quantitative analysis.
Qualitative data analysis was obtained from questionnaires and quantitative data
obtained from the results of the pre-test and post-test at the implementation
stage. Based on the results of the calculation of the data, it was obtained
that the data were normally distributed and homogeneous, so that the inferior
statistical test used the Independent Sample T-Test with a significance value
of 0.05. Based on the test results of data analysis, it was found that the
"child-friendly ICT" textbook that had been developed was valid,
practical and effective. The results obtained prove that child-friendly ICT
textbooks contribute to improving the professional competence of students. Child-friendly
ICT textbooks not only provide new understanding and knowledge of ICT use in
child-friendly learning, but also enhance the skills of prospective teachers in
using ICT-based teaching materials.
Radiosurgical treatment of trigeminal neuralgia: experience of the Radiosurgery Center of the N.V. Sklifosovsky Research Institute for Emergency Medicine
Authors: Tokarev A. S. , Sinkin M. V. , Rozhnova E. N. , Stepanov V. N. , Rak V. A. 
Published: September 2019

The study objective is to evaluate early results of radiosurgical treatment (RST) of drug-resistant trigeminal neuralgia (TN) of various etiology.Materials and methods. Between 01.01.2016 and 01.07.2018 at the Radiosurgery Center of the N.V. Sklifosovsky Research Institute for Emergency Medicine, 14 patients with drug-resistant TN underwent RST. Per magnetic resonance imaging, prior to treatment 7 patients had neurovascular conflict, 2 had demyelination of the root of the trigeminal nerve due to multiple sclerosis, and 5 patients showed no pathologies of the brain. Irradiation of the cisternal portion of the trigeminal nerve at the distance of 7.5 mm from the entry into the brainstem with prescribed dose of 90 Gy was performed. Follow-up period was 8–20 months. The difference in fractional anisotropy (FA) at the affected and healthy sides was evaluated in patients with TN prior to RST to divide them into 2 groups: with significant FA decrease and with moderate FA decrease.Results. All patients who underwent RST with PD >80 Gy (85.7 %) noted decreased level of pain or its full disappearance. In 11 (78.5 %) patients, anesthetic effect manifested itself 3–6 weeks after RST, in 1–3 months after RST. Full analgesic effect was achieved in a patient with idiopathic type II TN (PD 84 Gy) 3 months after RST, in a patient with neurovascular conflict and type I TN (PD 86 Gy) 6 weeks after RST, in a patient with multiple sclerosis and type I TN (PD 81 Gy) 3 weeks after RST. In the last-mentioned patient, pain returned 12 months after RST but with lower intensity. In 2 (14.3 %) patients (PD 80 Gy), no positive effect was observed in 6 months of follow up. Hypesthesia of a face area (RST complication) was diagnosed in only 1 (7.2 %) patient 8 months after RST, and it persisted for 6 weeks gradually regressing. There was no statistically significant correlation between FA decrease and RST outcome, but it was observed that outcome was more favorable in patients with moderately decreased FA.Conclusion. RST of drug-resistant forms of TN with PD >80 Gy significantly reduces pain syndrome 3–6 weeks after treatment and is characterized by low risk of complications.
High resolution passive speech mapping in dominant hemisphere glioma surgery
Authors: Sinkin M. V. , Osadchiy A. E. , Lebedev M. A. , Volkova K. V. , Kondratova M. S. , Trifonov I. S. , Krylov V. V. 
Published: September 2019

Background.Intraoperative brain mapping is one of the most critical stages of neurosurgical intervention in the eloquent area of the cerebral cortex. Traditionally direct cortical electrical stimulation is used for these purposes, but it can lead to seizures and loss of consciousness that makes it impossible to continue the procedure. Moreover, it significantly changes the surgery plan, especially in case of speech mapping during awake craniotomy.The study objectiveis to create a setup for intraoperative eloquent cortical areas passive mapping, and to compare informativity and safety of passive and active speech mapping.Materials and methods.We have created and tested a mobile device for high-resolution mapping of the Broca’s area that uses the analysis of the desynchronization processes in high-gamma oscillations in 64 micro-contact grid electrode for electrocorticography during awake craniotomy when patient pronounces the objects and actions.Results.We found precise coincidence for localization of the Broca’s area, determined by analyzing of bioelectric signal obtained from the electrocorticography and cortical mapping performed by bipolar direct cortical stimulation using Penfield method.Conclusion.The passive cortical speech mapping expands the potentialities of neurosurgical operations in the eloquent area of the brain and can increase the number of patients for whom this study is achievable. Further studies needed to evolve algorithms and sets of stimuli to expand the list of functional zones that can be mapped passively.
Primary germ cell tumors of the central nervous system
Authors: Martynov B. V. , Martynov R. S. , Svistov D. V. 
Published: September 2019

The study objective is to describe current views on pathogenesis, molecular biology, diagnosis, treatment of primary germ cell tumors of the central nervous system, as well as treatment prognosis.Materials and methods. The review includes 51 literature sources (4 in Russian, 47 in English). All articles were published in the last 20 years.Results and conclusion. The review reflects both established principles and characteristics of the national protocol of treatment of germ cell tumors, treatment nuances determined by histological type of the tumor. The most effective treatment method for germ cell tumors are radiation and neoadjuvant chemotherapy. For non-germinal germ cell tumors chemotherapy with subsequent complete removal is optimal. Total tumor resection by itself is the ideal treatment of mature teratomas. In the future, molecular and cytogenetic studies will allow to additionally identify subtypes of germ cell tumors of the central nervous system which will become the basis of new directions for therapy, improved treatment results and methods of prognosis.
Obezite ile yeme davranışı, beden algısı ve benlik saygısı arasındaki ilişki
Authors: ELÇİ BOĞAZ Maşite , KUTLU Ruhuşen , CİHAN Fatma Gökşin 
Published: September 2019

Amaç: Bu araştırmada obezite ile yeme davranışları, beden algısı ve benlik saygısı arasındaki ilişkinin değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Tanımlayıcı ve kesitsel tipteki bu çalışmaya Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Aile Hekimliği Polikliniğine başvuran 18 yaş üstü, gönüllü, beden kitle indeksine (BKİ) göre 64’ü obez, 58’i fazla kilolu ve 65’i normal kilolu olmak üzere toplam 187 kişi katılmıştır. Katılımcılara sosyodemografik özelliklerin sorgulandığı anket, Hollanda Yeme Davranışı Anketi, Beden Algısı ve Rosenberg Benlik Saygısı Ölçeği uygulanmıştır.Bulgular: Katılımcıların BKİ gruplarına göre benlik saygısı puanları incelendiğinde, gruplar arasında istatistiksel açıdan anlamlı bir farklılık bulunmadı. Obez olan grubun beden algısı ortalama puanı diğer gruplara göre düşük olmasına rağmen üç grup arasında istatistiksel olarak anlamlı bir fark yoktu. Fazla kilolu olan grupta kısıtlayıcı yeme davranışının, normal kilolu ve obez olan gruba göre anlamlı olarak daha yüksek olduğu görülürken, duygusal yeme ve dışsal yeme davranışları arasında ilişki saptanmadı. Çalışmaya katılanlara kendi kilolarını nasıl değerlendirdikleri sorulduğunda obez olanların yalnızca 19’u (%29,7) kend¬ini obez olarak değerlendirirken, 42’si (%65,6) kendini fazla kilolu olarak algılamaktaydı. Sonuç: Obezitenin nedenlerini, yol açtığı psikolojik ve sosyal sorunları dikkate alarak hastalarını değerlendirip sağlıklı yeme davranışına özendiren hekimler obezitenin önlenmesi, tedavisi ve izleminde daha etkin ve başarılı olabilirler.
Ortopedik cerrahi sonrası erken dönem hastane mortalitesi ve etki eden faktörler
Authors: BEYAZ Salih 
Published: September 2019

Amaç: Çalışmamızın amacı erken dönem en yüksek hastane mortalitesine sahip ortopedik cerrahi prosedürü ve mortalite üzerine etki eden faktörleri saptamaktır.Gereç ve Yöntem: 1998-2016 yılları arasında ortopedik cerrahi geçirmiş 19.727 hasta çalışmaya dahil edildi. Bu hastalardan ameliyat sonrası dönemde ilk 30 gün içinde hastanede ölen 370 hastanın dosyası tarandı. Genel mortalite ortalamasının üzerinde olan hastalara uygulanan cerrahiler, yaş, cinsiyet, malignite varlığı, koroner arter hastalığı öyküsü, diyabet, hemodiyaliz, geçirilmiş serebrovasküler olay öyküsü, hipertansiyon varlığı ASA değerlendirme skoru ve anestezi şekilleri kaydedildi.Bulgular: Ortopedik cerrahi geçiren 19.727 hastadan 237 (%1.23) hastanın cerrahi sonrası erken dönem hastanede öldüğü saptadık. Mortalitesi en yüksek 4 cerrahi prosedür; ampütasyon cerrahisinde % 6.35, femur boyun kırığında %5.2, intertrokanterik kalça kırığında %4.2, vertebra cerrahisinde %2.6 olarak bulundu. Mortalite üzerine etki eden faktörler ampütasyon cerrahisi yapılan hastalarda yaş, erkek cinsiyet, hipertansiyon, ameliyatın genel anestezi altında yapılması, ve hastanın hemodiyalize giriyor olması, Yüksek ASA skorunun tüm cerrahi türlerinde istatistiksel olarak anlamlı bulundu.Sonuç: İleri yaş ve buna bağlı ek kronik hastalıklar, ortopedik cerrahi gerektiren hastaların mortalitesini etkilemektedir. Ampütasyon cerrahisi, ve bu cerrahiye sebep olan nedenlerden dolayı, mortalitesi en yüksek ortopedik cerrahidir.
Publons Peer Evaluation Metrics are not Reliable Measures of Quality or Impact
Authors: Goldstein Scott 
Published: September 2019

A Review of:
Ortega, J. L. (2019). Exploratory analysis of Publons metrics and their relationship with bibliometric and altmetric impact. Aslib Journal of Information Management, 71(1), 124– 136. https://doi.org/10.1108/AJIM-06-2018-0153
Abstract
Objective – To analyze the relationship between scholars’ qualitative opinion of publications using Publons metrics and bibliometric and altmetric impact measures.
Design – Comparative, quantitative data set analysis.
Setting – Maximally exhaustive set of research articles retrievable from Publons.
Subjects – 45,819 articles retrieved from Publons in January 2018.
Methods – Author extracted article data from Publons and joined them (using the DOI) with data from three altmetric providers: Altmetric.com, PlumX, and Crossref Event Data. When providers gave discrepant results for the same metric, the maximum value was used. Publons data are described, and correlations are calculated between Publons metrics and altmetric and bibliometric indicators.
Main Results – In terms of coverage, Publons is biased in favour of life sciences and subject areas associated with health and medical sciences. Open access publishers are also over-represented. Articles reviewed in Publons overwhelmingly have one or two pre-publication reviews and only one post-publication review. Furthermore, the metrics of significance and quality (rated on a 1 to 10 scale) are almost identically distributed, suggesting that users may not distinguish between them. Pearson correlations between Publons metrics and bibliometric and altmetric indicators are very weak and not significant.
Conclusion – The biases in Publons coverage with respect to discipline and publisher support earlier research and suggest that the willingness to publish one’s reviews differs according to research area. Publons metrics are problematic as research quality indicators. Most publications have only a single post-publication review, and the absence of any significant disparity between the scores of significance and quality suggest the constructs are being conflated when in fact they should be measuring different things. The correlation analysis indicates that peer evaluation in Publons is not a measure of a work’s quality and impact.
Does Pet Remedy reduce stress in dogs?
Authors: Buckley Louise Anne 
Published: September 2019

PICO question
In stressed dogs, does using a Pet Remedy diffuser, compared to not using one, result in lowered stress levels?
Clinical bottom line
Three studies were reviewed, two that investigated Pet Remedy and one that investigated Valerian (an active ingredient in Pet Remedy) on aspects of canine behaviour associated with stress. The highest quality study was a randomised controlled trial that found that Pet Remedy had no significant effect on particularly stress-susceptible dogs exposed to an acute stressor. The weakest quality study was a randomised controlled trial that found a significant positive effect, but had high levels of industry involvement, weak and incomplete scientific reporting and methodology, and was not peer-reviewed prior to publication. Thus, the findings are unreliable. The final study, which was a quasi-experimental, fixed treatment order, controlled trial, found a positive effect of environmentally applied Valerian (on its own) on behaviour in shelter dogs. However, experimental design limited interpretation of the findings in relation to canine stress reduction, and external validity in relation to applicability to Pet Remedy use is weak.
Where used as an adjunct, Pet Remedy is unlikely to do any direct animal welfare harm and may have a positive effect, based on studies that have unreliable findings and/or low external validity. However, unless further high quality research demonstrates a positive effect of Pet Remedy, veterinary professionals should be cautious about recommending it as an alternative to options with a stronger evidentiary basis, or as a delay to seeking more extensive professional support where needed. There is a need for further research to examine the efficacy of Pet Remedy on behavioural and physiological indices of canine stress reduction across a range of common stressful scenarios to further support veterinary professional decision making.
PROSPEK PENGEMBANGAN ES GABUS BUAH DAN SAYUR, CITA RASA JADUL KAYA VITAMIN
Authors: Mulya Astuti Zenita , Abdi Nusara Anindya , Vidya Anggraini Cisya , Wandhira Wimarnaya Viska , Fadhila Nurul , Yudhistira Bara 
Published: September 2019

<p><em>In this modern era, many snacks that are not safe for health are sold to children and they like them very much. This problem is very serious to note because it is related to children's health. To overcome or reduce this problem, created an innovation of healthy snacks that are rich in vitamins, namely Ice Cork Fruit and Vegetables from various types of vegetables such as carrots, mustard greens, and purple yams. Ice Cork Vegetables are made with the aim of increasing interest in vegetable consumption in children. The target is to attract the interest of children to eat delicious snacks, safe and healthy through EGAYUR (VEGE ICE). Because in general children like to eat snacks that are tasty and refreshing, cork ice for example. The method for realizing this idea is to create an entrepreneurial business program that produces EGAYUR (VEGE ICE). The first thing to do is to make an SOP for making EGAYUR (VEGE ICE). Then do the trial making of EGAYUR (VEGE ICE) products, do research on the taste variants that consumers like, then do the production process. In one production it will produce 75 products, which are done once a week for 4 months. So that the total production for one month is 75 products.</em><em></em></p><p><em>Keywords :<strong> </strong>i</em><em>ce cork, vegetables, vitamins </em></p>
Randomized controlled trial on the effect of YouTube surgical videos on procedural knowledge and perceived self-efficacy of surgery residents
Authors: Albarrak Abdullah Ahmed S , Alnefaie Faisal A , Almasoud Riyadh 
Published: September 2019

Abstract
Background Multiple factors have challenged the surgical training which led to the development of the instructional videos to hasten the proficiency in performing surgical procedures. However, their educational effect has not been objectively studied yet. This study aims at objectively assessing the effect of instructional videos along with the subjective assessment of the self-efficacy of the training residents. The videos used were selected from YouTube, which is a valuable resource currently because of its ubiquitous availability and cost effectiveness. Methods A stratified randomized controlled trial was performed using an objective assessment tool for the procedural knowledge along with a questionnaire to assess the effect of videos on the perceived self-efficacy of the residents. Results There was a significant positive effect of watching instructional videos on the procedural knowledge. Even though residents report positive experience with using the videos, there was no significant effect of videos on the self-efficacy scores as reported by the residents. Conclusion instructional videos improved the procedural knowledge of the residents. This positive observation of the use of the YouTube videos offers great opportunities for the educationalists to select from thousands of videos instead of making the videos themselves.
Effects of blended versus offline case-centered learning on academic performance and the development of critical thinking among undergraduate nursing students
Authors: Yu Zhenzhen , Shen Ling , Zhuang Jiayuan , Chen Yimin , Chen Meijing , Lin Yazhu , Hu Rong 
Published: September 2019

Abstract
Background Educational reform, especially methods of teaching, has been a focus among nursing educators. This study explored the impact of blended versus offline case-centered learning on academic performance and the development of critical thinking among undergraduate nursing students.Methods A total of 269 undergraduate nursing students in two classes were taught Medical Nursing for 1 year. The two classes were randomly allocated to the experimental group (151 students), which undertook blended learning, or the control group (118 students), which undertook offline learning. The primary outcomes were academic performance and critical thinking ability. The Critical Thinking Disposition Inventory-Chinese Version (CTDI-CV) was used.Results At baseline, the students in the control group exhibited superior performance to that observed in the experimental group regarding all seven Professional Basic courses. There was no significant difference in academic performance in the Medical Nursing course after applying the two teaching methods; however, the median score was slightly higher in the experimental group than in the control group. In addition, there was no significant difference in the development of critical thinking ability between the blended and offline learning groups. In the experimental group, there was significant improvement compared with baseline in one of the seven CTDI-CV dimensions: critical thinking self-confidence (p<0.05). In the control group, there was significant improvement compared with baseline in the total score (p<0.05) and two of the seven dimensions: truth-seeking (p=0.001) and systematicity (p=0.010).Conclusions Our study confirms the effectiveness of blended and offline learning (both based on case-centered learning) for academic performance and components of critical thinking among undergraduate nursing students. Blended and offline case-centered learning should be applied to other nursing subjects in future studies. Moreover, further efforts to improve teaching are warranted.
In silico Analysis of CadF epitope- based vaccine design against Campylobacter jejuni
Authors: Naseri Mona Mobalegh , Shams Saeed , Naseri Mohammad Moballegh , Bakhshi Bita 
Published: September 2019

Abstract
Background

To eradicate infectious diseases caused by microorganisms, vaccination is a popular strategy against them and can be an effective approach. Among vaccines, subunit vaccines have been used to be more effective against diseases. CadF protein of Campylobacter jejuni is one of the important antigens in the pathogenic process of the bacterium. So, the aim of this work was to do a bioinformatics study for the identification of epitope-based CadF vaccine, as a subunit vaccine.

Main body

CadF gene sequences were extracted from the NCBI database and suitable physic-chemical properties of CadF were evaluated by Protprom server. Some epitopes of the CadF protein with high affinity were detected by different servers, which were predicted based on MHC-peptide complex and B-cell epitopes. The results indicated that CadF is an antigenic and non-allergenic protein and provided a desirable structure for design vaccine. Among epitopes, LSDSLALRL was confirmed for the simulation of both of B and T cells. This 9-mers peptide was located in 135-143 sequences of CadF protein and interacted with HLA-A0101. The peptide isn’t allergen and has the ability to be an antigen for motivating immune system. Besides, the analysis implied that the epitope structure could allow designing a vaccine against C. jejuni.
Co-infection of Anaplasma and Ehrlichia in Hedgehogs from China.
Authors: Xiao Xiao , Han Hui-Ju , Qi Rui , Gong Xiao-Qing , Lei Si-Cong , Liu Jian-Wei , Qin Xiang-Rong , Zhou Chuan-Min , Fang Li-Zhu , Ma Xiao-Juan , Chu Min , Yu Xue-Jie 
Published: September 2019

Abstract
Hedgehogs ( Erinaceus amurensis ) is an insectivorous mammal frequently observed in the wild and around the residential areas. However, information about tick-borne diseases in this species is not well known. We investigated tick-borne rickettsial pathogens including Anaplasma , Ehrlichia, Candidatus . Neoehrlichia and Rickettsia in hedgehogs collected in central China. Hedgehogs were captured from Hubei and Jiangxi Province with living traps. PCR amplification and DNA sequencing showed that 26% (19/73) hedgehogs were positive to Anaplasma bovis, 20.5% (15/73) were positive to a tentative new Ehrlichia species; in addition, 13.7% (10/73) hedgehogs were positive to A. bovis and Ehrlichia simultaneously. Ca . Neoehrlichia and Rickettsia species was not detected among the 73 hedgehogs. We concluded that hedgehogs from central China were widely infected with Anaplasma and Ehrlichia , suggesting hedgehogs may play a role in the ecology of Anaplasma and Ehrlichia .