bluuebunny/crossref_metadata_2025_split huggingface dataset:
Postdischarge Nurse Home Visits and Reuse: The Hospital to Home Outcomes (H2O) Trial
Authors: Auger Katherine A. , Simmons Jeffrey M. , Tubbs-Cooley Heather L. , Sucharew Heidi J. , Statile Angela M. , Pickler Rita H. , Sauers-Ford Hadley S. , Gold Jennifer M. , Khoury Jane C. , Beck Andrew F. , Wade-Murphy Susan , Kuhnell Pierce , Shah Samir S. ,   on behalf of the H2O Trial study group
Published: June 2018

BACKGROUND:
Hospital discharge is stressful for children and families. Poor transitional care is linked to unplanned health care reuse. We evaluated the effects of a pediatric transition intervention, specifically a single nurse home visit, on postdischarge outcomes in a randomized controlled trial.

METHODS:
We randomly assigned 1500 children hospitalized on hospital medicine, neurology services, or neurosurgery services to receive either a single postdischarge nurse-led home visit or no visit. We excluded children discharged with skilled home nursing services. Primary outcomes included 30-day unplanned, urgent health care reuse (composite measure of unplanned readmission, emergency department, or urgent care visit). Secondary outcomes, measured at 14 days, included postdischarge parental coping, number of days until parent-reported return to normal routine, and number of “red flags” or clinical warning signs a parent or caregiver could recall.

RESULTS:
The 30-day reuse rate was 17.8% in the intervention group and 14.0% in the control group. In the intention-to-treat analysis, children randomly assigned to the intervention group had higher odds of 30-day health care use (odds ratio: 1.33; 95% confidence interval: 1.003–1.76). In the per protocol analysis, there were no differences in 30-day health care use (odds ratio: 1.14; confidence interval: 0.84–1.55). Postdischarge coping scores and number of days until returning to a normal routine were similar between groups. Parents in the intervention group recalled more red flags at 14 days (mean: 1.9 vs 1.6; P &lt; .01).

CONCLUSIONS:
Children randomly assigned to the intervention had higher rates of 30-day postdischarge unplanned health care reuse. Parents in the intervention group recalled more clinical warning signs 2 weeks after discharge.
Desafíos de la menstruación en niñas y adolescentes de comunidades rurales del pacífico colombiano
Authors: Ariza Ruiz Liany Katerine , Espinoza Menéndez Maria Juana , Rodriguez Hernández Jorge Martín 
Published: June 2018

Objetivo Comprender los desafíos y experiencias de la menstruación en niñas y adolescentes de comunidades rurales del pacífico colombiano.Métodos Investigación de carácter mixto: principalmente cualitativa y en menor medida cuantitativa, combinó el enfoque ecológico, la perspectiva de género, el enfoque diferencial y el abordaje intercultural. Los participantes fueron niñas y adolescentes, jóvenes, profesoras/profesores y rectores de instituciones educativas, madres y padres familia, así como actores institucionales de secretarías de salud y educaciónmunicipales, y de los ministerios de Salud, Educación y del Viceniministerio de Agua y Saneamiento. Se llevaron a cabo grupos focales, entrevistas a profundidad, encuestasy observaciones de las condiciones sanitarias y de higiene de las instituciones educativas.La investigación fue realizada en los municipios de Bagadó (Chocó), Ipiales (Nariño) y Santander de Quilichao (Cauca).Resultados Se identificó que la insuficiente información al momento de la menarquia, el dolor, precario acceso a baños, agua y materiales absorbentes, sumados a los prejuiciosexistentes, hacen que la menstruación se experimente con pena y ocultamiento. Todo esto incide sobre el ausentismo a clases y en el fortalecimiento de prejuiciosentorno al “ser mujer”. La inequidad en niñas y adolescentes, derivados de las construccionesen torno a la menstruación, pasa desapercibido por las escuelas, familias,entidades y funcionarios encargados de la gestión de políticas públicas.Conclusiones Las construcciones sociales y culturales sobre la menstruación en losmunicipios estudiados conllevan a su configuración como experiencia negativa, lo cualgenera y refuerza tabúes en torno a la menstruación, que se materializan en situacionesde inequidad, estigma y discriminación para niñas y adolescentes. En este contextoes fundamental el trabajo comunitario, así como el diseño de políticas públicas yacciones para fomentar la equidad de género.
EFFECT OF ORGANIC LOADING RATE ON THE PERFORMANCE OF ANAEROBIC CO-DIGESTION DIGESTER TREATING FOOD WASTE AND SLUDGE WASTE
Authors: Nga Dinh Thi 
Published: June 2018

This research was carried out to evaluate the effect of organic loading rate to the performance of anaerobic co-digestion digester treating organic fraction of food waste (FW) and sludge waste (SW) from wastewater treatment plant. The experiment was conducted in two runs: Run S50, substrate contained 50 % of FW and 50 % of SW in term of volatile solid (VS) concentration; Run S100 (control run) contained 100 % SW in the influent substrate. The experiment was performed in a 3L working volume reactor at ambient temperature with three levels of organic loading rate (OLR) as 2; 4; 6 kgVS/m3/day, the duration of experiment was 18 days for each level of OLR. As results, the average of biogas production rate (BPR) at OLR 2;4;6 kgVS/m3/day,in Run S50 and Run S100 was 390 – 520; 860 – 1220; 1140 - 2440 ml/day and 160 – 300; 560 – 640; 700 - 1400 ml/day, respectively. The maximum methane yield (mlCH4/gVSadded/day) of organic loading rate 2; 4; 6 kgVS/m3/day was 118.96; 326.49; 628.20 for Run S50 and; 58.28; 160.27; 255.54 for Run S100, respectively. In conclusion, Run S50 always produced higher biogas production rate and higher methane yield at all 3 OLR levels. The higer OLR could enhance BPR and methane yield but at OLR 6 kgVS/m3/day made unstable performance and high concentration of COD in the effluent. Therefore, in this experimental conditions it has better operation at OLR under 6 kgVS/m3/day for the stable performance of reactors.
SOME GLYCOSIDES ISOLATED FROM DESMODIUM GANGETICUM (L.) DC. OF VIET NAM
Authors: Ha Le Minh 
Published: June 2018

From the methanol extract of the leaves of Desmodium gangeticum collected in Me Linh, Ha Noi, we isolated 5 compounds. In which, there are four glycosides including (6S,9R)-roseoside (1), kaempferol-3-O-rutinoside (nicotiflorin) (2), quercetin-3-O-rutinoside (rutin) (3), β-sitosterol-3-O- β-D-glucopyranoside (4), and the other is protocatechuic acid (5). Kaempferol-3-O-rutinoside (2) was isolated from Desmodium gangeticum for the first time while (6S,9R)-roseoside (1) was isolated from the genus Desmodium for the first time. Their structures were determined by 1D and 2D NMR spectra.
EPOXY/TITANATE MODIFIED NANOSILICA COMPOSITES: MORPHOLOGY, MECHANICAL PROPERTIES AND FRACTURE TOUGHNESS
Authors: Minh Ho Ngoc 
Published: June 2018

In this paper, the effect of modified nanosilica as a reinforcement agent on the performance of epoxy resin using tetrabutyl titanate (TBuT) hardener were investigated. Morphology of the epoxy/modified silica composites was determined by Scanning Electron Microscopy (SEM) method. Impact strength and flexural strength of the composites were measured by Charpy impact test and three-point bending test mode methods, respectively. Fracture toughness and fracture energy were calculated according to pre-cracked, single edge notched method with specimens in three-point bending geometry and suitable equations. The mechanical properties and fracture toughness of composites were significantly enhanced with loading nanosilica content to 5 wt.%.
Association of Immune-Related Adverse Events with Clinical Benefit in Patients with Advanced Non-Small-Cell Lung Cancer Treated with Nivolumab
Authors: Toi Yukihiro , Sugawara Shunichi , Kawashima Yosuke , Aiba Tomoiki , Kawana Sachiko , Saito Ryohei , Tsurumi Kyoji , Suzuki Kana , Shimizu Hisashi , Sugisaka Jun , Ono Hirotaka , Domeki Yutaka , Terayama Keisuke , Nakamura Atsushi , Yamanda Shinsuke , Kimura Yuichiro , Honda Yoshihiro 
Published: June 2018

Abstract

Background
Immune-related adverse events (irAEs) are frequently observed with nivolumab monotherapy. This study aimed to evaluate whether the development of irAEs correlates with treatment response in advanced non-small-cell lung cancer (NSCLC).

Patients and Methods
We conducted a retrospective study of patients who received nivolumab monotherapy at Sendai Kousei Hospital (n = 70). The patients were categorized into two groups based on the incidence of irAEs: those with irAEs (irAE group) or those without (non-irAE group). Treatment efficacy was evaluated in each group. The patients were further categorized into responders and nonresponders, and predictive factors of treatment response were determined.

Results
The objective response rate was 57% in the irAE group versus 12% in the non-irAE group. Median progression-free survival was 12.0 months in the irAE versus 3.6 months in the non-irAE group. The incidence of both irAEs and pre-existing antithyroid antibody was significantly higher in responders than in nonresponders. Multivariate analysis identified incidence of irAEs and pre-existing antithyroid antibody as an independent predictor of treatment response.

Conclusion
Objective response rate and progression-free survival were significantly better in the irAE than in the non-irAE group in patients with advanced NSCLC treated with nivolumab monotherapy. The development of irAEs was associated with clinical efficacy, and the presence of pre-existing antithyroid antibody might be correlated with treatment response to nivolumab monotherapy.

Implications for Practice
Immune-related adverse events (irAEs) are frequently observed with nivolumab monotherapy. This study evaluted whether the development of irAEs correlates with treatment response in advanced non-small-cell lung cancer. Results showed that the objective response rate and progression-free survival were significantly better in the patients who developed irAEs than in the patients who did not develop irAEs, and the incidence of irAEs and positivity for antithyroid antibody at pretreatment were independent predictors of treatment response of nivolumab monotherapy. Therefore, the development of irAEs predicts clinical benefit and suggests that cautious management of irAEs can lead to achieving maximum clinical benefit from nivolumab monotherapy.
Research on safety management of engineering construction
Authors: Yang Le , Zhang Haifeng , Zhao Suran , Hu Yulin , He Zhiyin 
Published: June 2018

The rapid economic growth in China has promoted the development of all walks of life. The most prominent is the construction industry. The safety management of the project construction during the construction process is very important. If there is a safety problem in construction, it will not only affect the progress of the construction, but serious loss of people and property will occur. Therefore, we should pay more attention to the safety management of the construction. Therefore, we should strengthen the management of safety management and improve the prevention of safety technology. Only under the premise of safety can the progress of the construction work be normal and the requirements of the project before the design are reached. Today we are in the engineering construction safety management problem is analyzed, and the problems of construction safety management is put forward rationalization proposals, prevent the occurrence of all kinds of problems in the engineering construction, to ensure security in project construction.
Biochemical bone markers in children with steroid sensitive nephrotic syndrome in remission
Authors: Sinha Neha , Wade Poonam , Ghildiyal Radha Gulati , Maniar Hemil 
Published: June 2018

Background: Glucocorticoids, the recommended first line treatment of steroid sensitive nephrotic syndrome (SSNS), are notorious for causing osteoporosis. There are very few studies from tropical countries looking at the lasting effects of a short course of glucocorticoids in SSNS. The objective is to study the effect of glucocorticoids and its dose on Vitamin D levels and biochemical markers of calcium metabolism in children with SSNS and to formulate a criterion to administer prophylactic calcium and vitamin D supplementation to such patients.Methods: A cross-sectional case-control study was conducted on 30 children with SSNS in remission and 30 healthy controls. Serum levels of 25 hydroxycholecalciferol [25(OH)D], calcium, phosphorous, albumin, alkaline phosphatase (ALP) and intact parathyroid (PTH) were measured. Total glucocorticoid exposure during the illness was summarized.Results: Children with SSNS had significantly lower height [median-100.00 (interquartile range {IQR}- 14.5) vs. controls [115.50 (17.5)] cm; P= 0.0003. Serum ALP levels was significantly higher in the cases [median 264 (IQR-80.7)] IU/L vs. controls [median 234 (IQR- 132)] IU/L; P= 0.028. Though hypovitaminosis D was universal in the study cohort; children with SSNS had worse Vitamin D status (76.7%) than healthy controls (50%). Levels of serum calcium, phosphorous, vitamin D and PTH were not significantly different between the two groups, nor were they related to total cumulative dose of steroid. Vitamin D levels showed no significant co-relation with number of relapses, age, calcium, phosphate, ALP, or PTH levels.Conclusions: Children with SSNS may benefit from routine measurement of 25 (OH) D and prophylactic supplementation with calcium and Vitamin D.
The survival mechanism of Home Industries (UMKM) of poor families after a disaster
Authors: Asiyah Udji 
Published: June 2018

The numerous forms of dependent UMKMs actors and their financial deficit, as well as the threat of poverty, should be prevented by using the substitute institutions that will be able to fulfill the needs of UMKMs in terms of capital, fulfilment of raw materials and marketing activities. The flood of Bengawan Solo River is often served as an annual problem faced by the UMKM in the disaster prone areas. The aim of this research is to formulate contextual intervention policies and programs, especially for community empowerment of home industries (UMKM) actors who are the disasters victims. This research used quantitative method. The data collection technique is interview with the total number of respondents 100 poor families who rely on their daily lives from business industries (UMKM) and in-depth interview to the ten selected informants. Among the UMKM actors who are looking for capital loans for new business start-up, seems to be the most common way to survive. When the prospect to expand the business is believed to be still there, then a respondent will try to rebuild his business from the bottom. However, when they feel there is no opportunity to restart their businesses, then the mechanism is trying to find another job to survive the survival of his family. The efforts to empower UMKM in disaster prone areas cannot be done by relying on a charitable programs and activities, but most importantly is how to awaken, give opportunities and empower UMKM actors in the real sense.
Prevention of Underage Drinking on California Indian Reservations Using Individual- and Community-Level Approaches
Authors: Moore Roland S. , Gilder David A. , Grube Joel W. , Lee Juliet P. , Geisler Jennifer A. , Friese Bettina , Calac Daniel J. , Finan Laura J. , Ehlers Cindy L. 
Published: June 2018

Objectives. To evaluate combined individual- and community-level interventions to reduce underage drinking by American Indian/Alaska Native (AI/AN) youths on rural California Indian reservations. Methods. Individual-level interventions included brief motivational interviewing and psychoeducation for Tribal youths. Community-level interventions included community mobilization and awareness activities, as well as restricting alcohol sales to minors. To test effects, we compared 7 waves of California Healthy Kids Survey data (2002–2015) for 9th- and 11th-grade AI/AN and non-AI/AN students in intervention area schools with California AI/AN students outside the intervention area (n = 617, n = 33 469, and n = 976, respectively). Results. Pre- to postintervention mean past 30-day drinking frequency declined among current drinkers in the intervention group (8.4–6.3 days) relative to comparison groups. Similarly, heavy episodic drinking frequency among current drinkers declined in the intervention group (7.0–4.8 days) versus the comparison groups. Conclusions. This study documented significant, sustained past 30-day drinking or heavy episodic drinking frequency reductions among AI/AN 9th- and 11th-grade current drinkers in rural California Indian reservation communities exposed to multilevel interventions. Public Health Implications. Multilevel community-partnered interventions can effectively reduce underage alcohol use in this population.
Industry Support of Patient Advocacy Organizations: The Case for an Extension of the Sunshine Act Provisions of the Affordable Care Act
Authors: McCoy Matthew S. 
Published: June 2018

Patient advocacy organizations (PAOs) have long been regarded as important representatives of patient and caregiver interests in health policy debates. Recently, however, PAOs have attracted increased scrutiny over their financial ties to drug and device companies. In the past year, researchers and policymakers have called for the creation of a “sunshine law” requiring mandatory public reporting of industry payments to PAOs. Others have suggested that increased transparency would do little to address, and may even exacerbate, underlying concerns about proindustry bias among industry-funded PAOs. To date, however, the benefits of a sunshine law have not been well articulated, nor have objections to the idea been carefully addressed. In particular, little attention has been paid to clarifying the merits of statutorily mandated disclosure relative to those of increased voluntary disclosure by PAOs. I examine arguments for and against a sunshine law and conclude that the balance of reasons supports the enactment of such a law.
Dryland Pea Production and Water Use Responses to Tillage, Crop Rotation, and Weed Management Practice
Authors: Lenssen Andrew W. , Sainju Upendra M. , Jabro Jalal D. , Allen Brett L. , Stevens William B. 
Published: June 2018

Core Ideas
Management strategies for dryland pea production and soil water use are lacking.
Tillage, crop rotation, and weed management effect on pea production were studied.
Pea growth and yield and water use increased with diversified crop rotation.
Increased seeding rate and stubble height also increased pea yield and water use.
Diversified crop rotation and improved weed management can enhance pea production.
Pea (Pisum sativum L.) has been used to replace fallow and to sustain dryland crop yields in arid and semiarid regions, but information to optimize its management is required. We evaluated pea growth, yield, and water use in response to tillage, crop rotation, and weed management practice from 2005 to 2010 in the northern Great Plains, United States. Tillage systems were no‐tillage and conventional tillage, and crop rotations were spring wheat (Triticum aestivum L.)–pea (W‐P), spring wheat–forage barley (Hordeum vulgaris L.)–pea (W‐B‐P), and spring wheat–forage barley–corn (Zea mays L.)–pea (W‐B‐C‐P). Weed managements were traditional (conventional seeding rates, early planting, broadcast N fertilization, and reduced stubble height) and improved (variable seeding rates, delayed planting, banded N fertilization, and increased stubble height) practices. Pea plant stand, height, pod number, grain and biomass yields, and water‐use efficiency (WUE) were 4 to 23% greater with the improved than the traditional weed management practice, but seed number per pod was 5% greater with the traditional practice. Plant height, pod number, biomass and grain yields, preplant and postharvest soil water contents, and WUE were 2 to 51% greater with W‐B‐P and W‐B‐C‐P than W‐P. Pea yield and WUE increased with extended crop rotation with nonlegumes and the improved weed management due to enhanced plant growth and seed characteristics as a result of greater soil water availability, seeding rate, and wheat stubble height. Dryland pea yield and water use can be enhanced by using extended diversified crop rotations and by increasing seeding rate and wheat stubble height.
Model Perkuliahan Pendidikan Agama Islam Yang Damai, Moderat, dan Toleran
Authors: Rahmat Munawar 
Published: June 2018

The study aims to describe the model of Islamic Religious Education (PAI) lectures that are peaceful, moderate, and tolerant in Indonesia University of Education (UPI). The research method used is descriptive-qualitative. The study found that the peaceful, moderate, and tolerant model of Islamic Education is to use open-ended lecture models that include the openness of lecturers, materials and methods. The openness of the lecturer is shown by the attitude and the thinking of the lecturer who sees the difference of understand, madzhab and religion as necessity and not exclusive, material disclosure is shown by substantive and inclusive material selection, while method openness is demonstrated by the use of an argumentative dialogical learning method consisting of ushul study cross-mazhab method, methodology of madhahab typhology and method of study of religions. AbstrakPenelitian bertujuan mendeskripsikan model perkuliahan PAI yang damai, moderat, dan toleransi di Universitas Pendidikan Indonesia (UPI) Bandung. Metode penelitian yang digunakan deskriptif-kualitatif. Penelitian menemukan bahwa Model Pendidikan Agama Islam yang damai, moderat, dan toleran yaitu menggunakan model perkuliahan yang terbuka yang meliputi keterbukaan dosen, materi dan metode. Keterbukaan dosen ditunjukkan dengan sikap dan pemikiran dosen yang melihat perbedaan paham, mazhab dan agama sebagai keniscayaan dan tidak bersifat eksklusif; keterbukaan materi ditunjukkan dengan pemilihan materi secara substantive dan inklusif,sedangkan keterbukaan metode ditunjukkan dengan penggunaan metode pembelajaran yang dialogis argumentatif yang terdiri dari metode studi ushul lintas mazhab, metode tipologi mazhab dan metode studi agama-agama.