bluuebunny/crossref_metadata_2025_split huggingface dataset:
<b>Parasitological findings and antiparasitic treatment of captive Jaguarundis <I>Herpailurus yagouaroundi</I> (Carnivora: Felidae) in a conservation center in Brazil</b>
Authors: Grossmann Nárjara Veras , De Sousa Anderson Silva , Cardoso Rebecca Martins , Hoppe Estevam Guilherme Lux 
Published: June 2018

Ex situ management of wildlife provides a possibility for species maintenance, research development and environmental education. But as captive facilities are usually much smaller than the area occupied by a species in the natural habitat, cleaning might be insufficient, domestic species such as cats might be in close proximity, and wild animals in captivity are inevitably stressed, animals kept in these facilities are more at risk of acquiring parasitic infections. Therefore, an appropriate prophylactic protocol and consequent anti-parasitic therapy of affected animals are fundamental for any wildlife conservation center. This report describes the procedures adopted in a conservation center for wild felines in which four adult Jaguarundis were diagnosed with severe infection with gastrointestinal parasites and flea infestation. Two animals died and based on the necropsy findings and fecal examinations, infections with Ancylostoma caninum and Toxocara cati were diagnosed, as well as severe infestations with Ctenocephalides felis felis fleas, all common parasites of domestic cats. We discuss the applied therapy and the adopted environmental management, along with the importance of regular health assessments and a preventive medicine program for this species in captivity.
<b><I>Polytrias indica</I> (Poaceae: Andropogoneae): the name, species identity and its distribution in India</b>
Authors: Raju Vatsavaya S. , Kumar V. Sampath 
Published: June 2018

Polytrias indica (Houtt.) Veldkamp is native to Java (Indonesia) but found outside its native range as a lawn grass or an escape. In India, it was first collected from Khasia (now Khasi) in Meghalaya and later reported as a garden escape in Indian Botanic Garden, Shibpur, West Bengal. Merrill created the confusion when he made the combination Ischaemum indicum (1938) for a taxon which is not an Ischaemum. The so-called Polytrias indica in certain Indian herbaria (e.g., PBL, BSID) is, indeed, Ischaemum ciliare Retz. (1791) to which name Ishaemum indicum has been misapplied in Indian grasses literature, and the IUCN assessment of Polytrias indica made in 2013 is not an exception.
<b>Notes on the taxonomy and distribution of the Bengal Morning Glory <I>Ipomoea rubens</I> Choisy (Convolvulaceae) in India</b>
Authors: Swamy J. , Ramana Pragada Venkata 
Published: June 2018

Ipomoea rubens Choisy (Convolvulaceae) is a species originally described from India and native to the Old World. It was hitherto recorded in India only from the states of Assam and the northern part of West Bengal but is now reported for the first time from the coast of Andhra Pradesh. A detailed description, photographs and notes are provided.
<b>A first report and additional description of the assassin bug <I>Neostaccia plebeja</I> (Stål) (Heteroptera: Reduviidae) from India with comparative notes on <I>Staccia diluta</I> Stål from Assam, India</b>
Authors: Sarode Balasaheb V. , Boyane Swapnil S. , Ghate Hemant V. 
Published: June 2018

The assassin bug, Neostaccia plebeja (Stål, 1866) (Hemiptera: Heteroptera: Reduviidae: Stenopodainae) is being reported for the first time from India. It is redescribed with many illustrations. Comparative photos of the salient characters of Staccia diluta Stål, 1859 are also provided.
High Burden of 30‐Day Readmissions After Acute Venous Thromboembolism in the United States
Authors: Secemsky Eric A. , Rosenfield Kenneth , Kennedy Kevin F. , Jaff Michael , Yeh Robert W. 
Published: June 2018

Background

Venous thromboembolism (
VTE
) is the third leading cause of vascular disease and accounts for $10 billion in annual US healthcare costs. The nationwide burden of 30‐day readmissions after such events has not been comprehensively assessed.

Methods and Results

We analyzed adults ≥18 years of age with hospitalizations associated with acute
VTE
between January 1, 2010, and December 31, 2014, in the Nationwide Readmissions Database.
International Classification of Disease, Ninth Revision, Clinical Modification
(

ICD
‐9‐

CM
)

codes were used to identify hospitalizations associated with acute pulmonary embolism or deep vein thrombosis. The primary outcome was the rate of unplanned 30‐day readmission. Hierarchical logistic regression was used to calculate hospital‐specific 30‐day risk‐standardized readmission rates, a marker of healthcare quality. Among 1 176 335 hospitalizations with acute
VTE
, in‐hospital death occurred in 6.2%.
VTE
was associated with malignancy in 19.7%, recent surgery in 19.3%, recent trauma in 4.6%, hypercoagulability in 3.3%, and pregnancy in 1.0%. Among survivors to discharge, the 30‐day readmission rate was 17.5%, with no significant difference in rates across study years (17.4%–17.7%;
P
=0.10 for trend). Major predictors of readmission were malignancy (relative risk, 1.49, 95% confidence interval 1.47‐1.50), Medicaid insurance (relative risk, 1.48, 95% confidence interval 1.46‐1.50), and nonelective index admission (relative risk, 1.31, 95% confidence interval 1.29‐1.33). Top causes of readmission included sepsis (9.6%) and procedural complications (8.1%). Median rehospitalization costs were $9781.7 (interquartile range, $5430.7–$18 784.1), and 8.1% died during readmission. The interquartile range in risk‐standardized readmission rates was 16.6% to 18.3%, suggesting modest interhospital heterogeneity in readmission risk.

Conclusions

Nearly 1 in 5 patients with acute
VTE
were readmitted within 30 days. Predictors and causes of readmission were primarily related to patient characteristics and complications from comorbid conditions, whereas healthcare quality had a moderate impact on readmission risk.
Fold, Hexagonal
Authors: Park Joo Yeon 
Published: June 2018

Abstract
Fold, Hexagonal presents the impossibility of entering into the language of others and suggests the ways in which such an exclusion can open up a space of imagination around words. This space of imagination includes the visual and bodily experiences of language as well as the physical space that writing occupies. The “Hexagonal” of the title alludes to the infinite hexagonal rooms featured in Jorge Luis Borges's short story “The Library of Babel” and also evokes an open-ended linguistic space. The project features hexagonal forms staged on folded, lined paper, reflected and fragmented by multiple mirrors that alter their directions and dimensions and suggest the ruin of Borges's library. Sentences describing the folding, reflecting, and refracting of lines, diagonals, squares, rectangles and hexagons are written with English letters forced into squares designed for Korean syllabic blocks. These form grammatically correct but scarcely legible forms whose process of inscription slows the apprehension of their meaning. What Walter Benjamin calls “pure language” is imagined here through a process of translation that is always a becoming, a translation that follows the unending continuation of a fold.
Sibling Relationships in Adoptive Families That Disrupted or Were in Crisis
Authors: Selwyn Julie 
Published: June 2018

Purpose: The study investigated whether sibling relationships influenced the outcomes of a sample of adoptive placements in England and Wales that had broken down postorder or were in crisis. Method: The study used secondary analysis drawing on in-depth interviews with 41 families who had experienced an adoption disruption and 42 families who described the adoptive placement as being in crisis in England and in Wales. The families contained 214 adopted and birth children. Results: Siblings placed together were statistically more likely to disrupt in comparison with sequential placements. Only 18 of the 83 families described normal sibling relationships. Placements intended to maintain sibling relationships had not done so. Conclusion: Assessments need to pay more attention to sibling dynamics. Children’s relationships might be better supported by separate placements with planned contact. Interventions are needed to improve sibling relationships.
The Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition on Sterol Absorption Markers in a Cohort of Real-World Patients
Authors: Brandt Eric J. , Benes Lane B. , Lee Linda , Dayspring Thomas D. , Sorrentino Matthew , Davidson Michael 
Published: June 2018

Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is expressed in multiple tissues, including the small intestine. The effect of PCSK9 inhibition on cholesterol absorption is not known. Objectives: Measure serum cholesterol absorption markers before and after initiation of PCSK9 inhibitors. Methods: Single-center retrospective cohort of patients administered evolocumab and alirocumab between July 2015 and January 2017. Paired t tests were used to compare mean serum cholesterol marker concentrations, and ratios to total cholesterol, before and after PCSK9 inhibitor initiation. Analyses were repeated for those taking and not taking statins and taking or not taking ezetimibe at both initiation and follow-up, for each PCSK9 inhibitor, and based on follow-up time (<60, 60-120, and >120 days). Results: There were 62 possible participants, 34 were excluded for lack of data or unknown PCSK9 inhibitor initiation date. Average follow-up was 92.5 days. Mean campesterol (before 3.14 μg/mL, 95% CI: 2.79-4.38 μg/mL; after 2.09 μg/mL, 95% CI: 1.87-2.31 μg/mL; P < .0001), sitosterol (before 2.46 μg/mL, 95% CI: 2.23-2.70 μg/mL; after 1.62 μg/mL, 95% CI: 1.48-1.75 μg/mL; P < .0001), and cholestanol (before 3.25 μg/mL, 95% CI: 3.04-3.47 μg/mL; after 2.08 μg/mL, 95% CI: 1.96-2.21 μg/mL; P < .0001) all significantly decreased at follow-up. There was no significant change in absorption marker to total cholesterol ratios. Findings were not influenced by statin or ezetimibe use or nonuse, which PCSK9 inhibitor was prescribed, or time to follow-up. Conclusion: Proprotein convertase subtilisin/kexin type 9 inhibition was associated with decreased cholesterol absorption markers.
Tele-delivered mindfulness-based cognitive therapy in chronic obstructive pulmonary disease: A mixed-methods feasibility study
Authors: Farver-Vestergaard Ingeborg , O’Connor Maja , Smith Nina C , Løkke Anders , Bendstrup Elisabeth , Zachariae Robert 
Published: June 2018

Introduction Mindfulness-based cognitive therapy has been shown to reduce psychological distress in chronic obstructive pulmonary disease, but uptake and attendance rates of hospital-based, face-to-face mindfulness-based cognitive therapy are low. The present mixed-methods study evaluates the clinical feasibility of home-based, tele-delivered mindfulness-based cognitive therapy in chronic obstructive pulmonary disease. Methods Eight patients with chronic obstructive pulmonary disease (mean age: 72.6 years; 50% female) received a standardised eight-week mindfulness-based cognitive therapy programme delivered via home-based video-conferences in groups of four. Feasibility in relation to (a) clinical change, (b) attendance and (c) instructor-patient working alliance were evaluated with questionnaires and semi-structured interviews. Results Statistically non-significant reductions in psychological distress (Cohen’s d = 0.504; p = 0.399) and physical health status impairment ( d = 0.743; p = 0.156) were observed from pre- to post-intervention. Participant narratives about clinical outcomes focused on changes in how to relate to unpleasant sensations, i.e. through attentional flexibility, taking a pause and acceptance. The average attendance rate was 7.5 (standard deviation = 0.8) out of eight sessions and no participants dropped out. The tele-based format appeared to accommodate participants’ planning difficulties and promoted their ability and wish to participate. Although participant narratives suggested the tele-based format to be a barrier to developing a trusting and safe therapeutic environment, working alliance questionnaire scores were comparable to those found for face-to-face mindfulness-based cognitive therapy. Discussion The preliminary results indicate that tele-delivered mindfulness-based cognitive therapy is a clinically feasible intervention in chronic obstructive pulmonary disease. Future large-scale, randomised controlled trials testing its efficacy on the outcomes of psychological distress and physical health status should include analyses of potential mediators and moderators of the effect as well as and careful monitoring of attendance and adverse events.
Impact of relative dose intensity in gemcitabine–cisplatin chemotherapy for metastatic urothelial carcinoma
Authors: Kohei Naoki , Sugiyama Kyohei , Chihara Ichiro , Muro Yusuke , Imamura Masaaki , Nishio Yasunori , Yoshimura Koji 
Published: June 2018

Objectives: To evaluate the impact of relative dose intensity for gemcitabine–cisplatin chemotherapy in patients with metastatic urothelial carcinoma. Methods: We retrospectively reviewed the medical records of 18 patients with metastatic urothelial carcinoma, who received gemcitabine–cisplatin regimen as the first-line chemotherapy between 2009 and 2015. The doses of gemcitabine and cisplatin were reduced or the intervals between treatment cycles were prolonged according to the treatment efficacy and adverse events during the first and second cycles. The individually optimal relative dose intensity was set as the actual dose per the standard dose in the first and second cycles. From the third course onward, patients received the gemcitabine–cisplatin chemotherapy with the same relative dose intensity. Overall survival was compared with the groups according to the value of relative dose intensity. Results: The median age was 72.5 (range, 56–79) years and 15 men and 3 women were enrolled in the study. The median number of cycles of first-line gemcitabine–cisplatin chemotherapy was 8 (range, 2–17), and the median survival time from initiation of first-line chemotherapy was 20.1 (range, 3.5–32.8) months. The total median relative dose intensity of gemcitabine–cisplatin chemotherapy was 56.1%. The median survival time of 10 patients in the group with the relative dose intensity of less than 60% was significantly longer than that of 8 patients in the group with the relative dose intensity of more than 60% (19.2 and 11.0 months, respectively, p = 0.04). Conclusion: Individual low relative dose intensity management in the first-line gemcitabine–cisplatin chemotherapy may be an acceptable option for patients with metastatic urothelial carcinoma.
Harboring Contaminants in Repeatedly Reprocessed Pedicle Screws
Authors: Agarwal Aakash , Schultz Christian , Agarwal Anand K. , Wang Jeffrey C. , Garfin Steve R. , Anand Neel 
Published: June 2018

Study Design: It consisted of evaluation of the pedicle screws for presence of residual nonmicrobial contaminants and tabulation of the minimum steps and time required for reprocessing implants as per guidelines and its comparison with actual practice. Objective: An evaluation of the nonmicrobial contaminants prevalent on the pedicle screws used for spine surgery and the underlying practice cause behind the source. Methods: The first component consisted of a random selection of 6 pedicle screws and its assessment using optical microscopy, scanning electron microscopy with energy dispersive spectroscopy, and Fourier transform infrared spectroscopy. The second component consisted of review of implant reprocessing guidelines and its applicability. Results: Three types of contaminants were identified: corrosion, saccharide of unknown origin, and soap residue mixed with and were mostly present at the interfaces with low permeability. In addition, manufacturer’s guideline recommends 19 hours of reprocessing, whereas the real-time observation revealed a turnaround time of 1 hour 17 minutes. Conclusion: Repeatedly reprocessed pedicle screws host corrosion, carbohydrate, fat, and soap, which could be a cause of surgical site infection and inflammatory responses postsurgery. The cause behind it is the impracticality of repeated cleaning and inspection of such devices.
Familial aggregation and heritability of sarcoidosis: a Swedish nested case−control study
Authors: Rossides Marios , Grunewald Johan , Eklund Anders , Kullberg Susanna , Di Giuseppe Daniela , Askling Johan , Arkema Elizabeth V. 
Published: June 2018

Sarcoidosis is believed to be caused by both genetic and environmental risk factors, but the proportion of the susceptibility to sarcoidosis that is mediated by genetics remains unknown. We aimed to estimate the familial aggregation and heritability of sarcoidosis using a case–control–family study design and population-based Swedish registers.We identified 23 880 individuals with visits for sarcoidosis in the Swedish National Patient Register using International Classification of Diseases codes (1964‒2013). Information on Löfgren's syndrome was available for a subset diagnosed at Karolinska University Hospital (Stockholm, Sweden). General population controls were matched to cases (10:1). Relatives of cases and controls were identified from the Swedish Multi-Generation Register and ascertained for sarcoidosis in the National Patient Register. We estimated familial relative risks for sarcoidosis using conditional logistic regression and heritability using biometric models.Having at least one first-degree relative with sarcoidosis was associated with a 3.7-fold increase in the risk of sarcoidosis (95% CI 3.4−4.1). The relative risk increased in those with two or more relatives (relative risk 4.7) and in Löfgren's syndrome (relative risk 4.1). The heritability was 39% (95% CI 12−65%).This large investigation showed that having a relative with sarcoidosis is a very strong risk factor for the disease. Genetic variation is an important, albeit partial, contributing factor to the risk for sarcoidosis.
Usefulness of the Korean Version of the CAGE-Adapted to Include Drugs Combined With Clinical Predictors to Screen for Opioid-Related Aberrant Behavior
Authors: Lee Chang-Soon , Kim Daehyun , Park Sang-Yoen , Lee Sang Chul , Kim Young-Chul , Moon Jee Youn 
Published: June 2018

BACKGROUND:
As national opioid consumption in South Korea has soared, well-validated screening tools for opioid use disorder (OUD) have become indispensable. The aims of our study were to evaluate OUD using the Korean version of the CAGE-Adapted to Include Drugs (CAGE-AID) and the CAGE-Opioid (an alternative version of the CAGE-AID), and to investigate clinical predictors that might be useful to screen for OUD in conjunction with the CAGE-AID/Opioid questionnaires.

METHODS:
A single-center, prospective, observational study was performed. After linguistic validation of the Korean version of the CAGE-AID/Opioid questionnaires, we assessed OUD in patients with chronic opioid treatment. Multivariable logistic models of the CAGE-AID/Opioid questionnaires combined with relevant clinical predictors were established. Then, the receiver operating characteristic curve analysis of the multivariable CAGE-AID/Opioid models was conducted to assess diagnostic accuracy to screen for OUD. Next, we calculated predicted probability with >85% sensitivity and >50% specificity in each CAGE-AID and CAGE-Opioid model. Using the optimal value of the predicted probability, a cutoff score of the CAGE-AID/Opioid questionnaires combined with the relevant clinical factors was suggested to screen for OUD.

RESULTS:
Among 201 participants, 51 patients showed ≥1 OUDs. In the multivariable regression model, male sex, comorbid neuropsychiatric disorder, and current heavy drinking significantly remained as clinical variables to predict OUD combined with the scores of the Korean CAGE-AID/Opioid questionnaire. The area under the curve was 0.77 (95% confidence interval, 0.71–0.83) for the CAGE-AID model and 0.78 (95% confidence interval, 0.71–0.83) for the CAGE-Opioid model. The optimal predicted probability values to screen for OUD in the CAGE-AID/Opioid models were >0.135 (sensitivity, 0.86; specificity, 0.52) and >0.142 (sensitivity, 0.86; specificity, 0.53), respectively. When we used these predictive probabilities, the cutoff score of the CAGE-AID/Opioid questionnaires ranged from 0 to 3, which was dependent on the presence of the relevant clinical variables in each model.

CONCLUSIONS:
In this study, one fourth of the total participants with chronic opioid treatment showed OUD in the Korean population. The multivariable models of the CAGE-AID/Opioid with sex, comorbid neuropsychiatric disorder, and current heavy drinking are valid parameters to screen for OUD, with the cutoff scores of the CAGE-AID/Opioid questionnaires ranging from 0 to 3 depending on the presence of the clinical variables.
Diplomacia financiera en la periferia global: entre la cooperación y la coerción. Aproximaciones teórico-empíricas a partir de las relaciones crediticias de Argentina con Venezuela y China
Authors: Fernández Alonso José Marcelino 
Published: June 2018

El objetivo del presente artículo es analizar las características reportadas por la diplomacia financiera entre los países de la periferia global durante los primeros años del siglo XXI. En términos específicos, el artículo enfoca su escrutinio en los lazos crediticios entretejidos por la República Argentina con la República Bolivariana de Venezuela y la República Popular China (RPC) en aras de sortear su marginación financiera internacional. A modo de hipótesis, el artículo sostiene que los canales y los dispositivos de diplomacia financiera articulados entre Argentina y Venezuela, y Argentina y la rpc resultaron habilitados tanto por la acumulación de reservas internacionales como por la afinidad político-identitaria, aunque condicionados por el grado de asimetrías entre las partes. Tras la validación empírica de la misma, el trabajo concluye que, aunque relevantes para la concreción de las operaciones crediticias, los factores habilitantes de la diplomacia financiera tuvieron una ponderación desigual: la afinidad político-identitaria (instancia ideacional) gravitó detrás de la disponibilidad de recursos (instancia material). Por otra parte, las modalidades que asumieron dichos canales y dispositivos estuvieron, en efecto, condicionadas por el grado de asimetría entre los Estados intervinientes. De este modo, los desequilibrios estructurales crecientes entre Argentina y la rpc redundaron en que las iniciativas de cooperación financiera se reconocieran ante todo signadas por una lógica coercitiva, en contraste con lo reportado con las vinculaciones con Venezuela.