bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of seasonal upwelling and runoff on water chemistry and growth and survival of native and commercial oysters
Authors: Hollarsmith Jordan A. , Sadowski Jason S. , Picard Manon M. M. , Cheng Brian , Farlin James , Russell Ann , Grosholz Edwin D. 
Published: August 2019

AbstractThe effects of climate change, including ocean acidification and ocean heatwaves, on biological communities in estuaries are often uncertain. Part of the uncertainty is due to the complex suite of environmental factors in addition to acidification and warming that influence the growth of shells and skeletons of many estuarine organisms. The goal of this study was to document spatial and temporal variation in water column properties and to measure the in situ effects on larval and recently settled stages of ecologically important Olympia oysters (Ostrea lurida) and commercially important Pacific oysters (Crassostrea gigas) in a low‐inflow estuary with a Mediterranean climate in Northern California. Our results reveal that seasonal inputs of upwelled or riverine water create important and predictable gradients of carbonate system parameters, temperature, salinity, dissolved oxygen (DO), and other variables that influence oyster performance, and that the influence of these gradients is contingent upon the location in the estuary as well as seasonal timing. During upwelling events (dry season), temperature, carbonate chemistry, and DO had the greatest impact on oyster performance. During runoff events (wet season), gradients in salinity, nutrient concentrations, and total alkalinity driven by river discharge were comparatively more important. These results suggest that the spatial importance of carbonate chemistry and temperature are seasonally variable and are two of several other factors that determine oyster performance. We use these results to discuss future impacts on oysters given projected regional changes in the frequency and magnitude of upwelling and precipitation‐driven runoff events.
Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1
Authors: Fultz Robert , Engevik Melinda A. , Shi Zhongcheng , Hall Anne , Herrmann Beatrice , Ganesh Bhanu P. , Major Angela , Haag Anthony , Mori‐Akiyama Yuko , Versalovic James 
Published: August 2019

AbstractThe histamine H2 receptor (H2R) is a G protein‐coupled receptor that mediates cyclic AMP production, protein kinase A activation, and MAP kinase signaling. In order to explore the multifaceted effects of histamine signaling on immune cells, phagocytosis was evaluated using primary mouse‐derived macrophages. Phagocytosis is initiated by signaling via surface‐bound scavenger receptors and can be regulated by autophagy. Absence of H2R signaling resulted in diminished phagocytosis of live bacteria and synthetic microspheres by primary macrophages from histamine H2 receptor gene (Hrh2)‐deficient mice. Flow cytometry and immunofluorescence microscopy were used to quantify phagocytosis of phylogenetically diverse bacteria as well as microspheres of defined chemical composition. Autophagy and scavenger receptor gene expression were quantified in macrophages after exposure to Escherichia coli. Expression of the autophagy genes, Becn1 and Atg12, was increased in Hrh2−/− macrophages, indicating upregulation of autophagy pathways. Expression of the Macrophage Scavenger Receptor 1 gene (Msr1) was diminished in Hrh2‐deficient macrophages, supporting the possible importance of histamine signaling in scavenger receptor abundance and macrophage function. Flow cytometry confirmed diminished MSR1 surface abundance in Hrh2−/− macrophages. These data suggest that H2R signaling is required for effective phagocytosis by regulating the process of autophagy and scavenger receptor MSR1 abundance in macrophages.
Quality of vitrified porcine immature oocytes is improved by coculture with fresh oocytes during in vitro maturation
Authors: Jia Bao‐Yu , Xiang De‐Cai , Zhang Bin , Quan Guo‐Bo , Shao Qing‐Yong , Hong Qiong‐Hua , Wu Guo‐Quan 
Published: August 2019

AbstractIt is essential to enhance the in vitro maturation (IVM) condition for immature oocytes after cryopreservation, particularly if limited numbers of oocytes collected from specific donors. The objective of this study was to determine if quality of vitrified porcine immature oocytes was enhanced by coculturing with fresh oocytes during IVM. To distinguish fresh versus vitrified oocytes, we used two types of coculture systems: (a) transwell two‐chamber coculture; (b) labeling and tracing fresh oocytes with CellTracker™ Green CMFDA during conventional culture. Coculture systems significantly accelerated meiotic progression of vitrified oocytes and significantly increased blastocyst formation rates following parthenogenetic activation and somatic cell nuclear transfer. Reactive oxygen species generation in vitrified oocytes was ameliorated by the coculture conditions, with no significant difference between fresh and vitrified oocytes for intracellular glutathione level. Both coculture systems significantly increased rate of normal mitochondrial distribution in vitrified oocytes, but did not affect fluorescence intensity of mitochondria. The percentage of oocytes with normal endoplasmic reticulum (ER) distribution and ER fluorescence intensity were significantly higher in vitrified oocytes cocultured with fresh oocytes. After 20 hr of IVM, mRNA expression of COX2, HAS2, PTX3, and TNFAIP6 remained significantly higher in cumulus cells derived from vitrified oocytes and coculture systems significantly decreased the expression of these genes. Additionally, coculture methods prevented the reduction of mRNA expression for BMP15, ZAR1, POU5F1, and DNMT3A in vitrified oocytes. In conclusion, oocyte quality and subsequent embryo development of vitrified porcine immature oocytes were significantly improved by fresh oocyte coculture during IVM.
Distributed model predictive control strategies for coordination of electro‐thermal devices in a cooperative energy management concept
Authors: Stoyanova Ivelina , Gümrükcü Erdem , Aragon Gustavo , Hidalgo‐Rodriguez Diego I. , Monti Antonello , Myrzik Johanna 
Published: August 2019

SummaryThis work discusses three promising strategies for the compensation of deviations within the online phase of a cooperative energy management concept. Whereas in the planning phase, hourly schedules for the active electro‐thermal devices are negotiated on a daily basis, the second phase tracks the schedule, including forecast updates, and compensates the deviations. The latter online compensation is realized with a distributed and hierarchical‐distributed model predictive control strategies, which are compared with continuous rescheduling with receding horizon and evaluated in terms of computational and optimization performance and scalability. The optimization is implemented and deployed using an open‐source optimization framework, which automatically manages optimization control, integration of renewable generation and load forecasts, multi‐instantiation and communication over an internet of things communication protocol. We address the case of significant deviations from the day‐ahead forecast and the tracking of an obsolete schedule and suggest a combined method, which combines the advantages of rescheduling and a distributed MPC strategy. The method applies a dynamic threshold to evaluate the deviation trend over time and to decide if compensation is still feasible or if a rescheduling should be triggered. The methods are evaluated based on several performance indicators such as residual deviation, number of switching events and computation and communication requirements and scalability, and offer a methodology for the control design of systems of different dimensions.
Comparison of Iridium(I) Catalysts in Temperature Mediated Hydrogen Isotope Exchange Reactions
Authors: Valero Mégane , Mishra Anurag , Blass Jennifer , Weck Remo , Derdau Volker 
Published: August 2019

AbstractThe reactivity and selectivity of iridium(I) catalysed hydrogen isotope exchange (HIE) reactions can be varied by using wide range of reaction temperatures. Herein, we have done a detailed comparison study with common iridium(I) catalysts (1–6) which will help us to understand and optimize the approaches of either high selectivity or maximum deuterium incorporation. We have demonstrated that the temperature window for these studied iridium(I) catalysts is surprisingly very broad. This principle was further proven in some HIE reactions on complex drug molecules.
Safety First!
Authors: Hauschild Dirk , Braam Daniel , Krasnaberski Alexei , Zhang Jennifer 
Published: August 2019

AbstractThe use of Lidar sensors for autonomous vehicles is a proven technology that will be designed into both current and coming generations of cars for a safer and more relaxed driving experience. To enable high‐precision detection of distances from the static and dynamic environment surrounding the cars, the laser beam must be shaped into a light field with a defined field of view. With the new glass diffuser technology from Limo, hot spot‐free light shaping and large illumination fields are combined to fully cover the 360° view with only four lidar systems while allowing operation in even the toughest environmental conditions.
Maleimidophenyl isocyanates as postpolymerization modification agents and their applications in the synthesis of block copolymers
Authors: Takashima Rikito , Kida Jumpei , Aoki Daisuke , Otsuka Hideyuki 
Published: August 2019

ABSTRACTThe maleimide structure is highly reactive, exemplified by thiol–ene click reactions with thiols and Diels–Alder reactions with furans. Although postpolymerization modifications and macromolecular conjugations involving maleimide units have been widely studied, mostly due to their selectivity and high reactivity, little has been reported on the one‐pot postpolymerization introduction of maleimides in polymer chains. Herein, we report p‐maleimidophenyl isocyanate and its derivatives as modification agents to introduce maleimide moieties by reaction with hydroxy groups into polymer chains. The high reactivity of the resulting modification agents and of the corresponding maleimide structures once inserted in the polymer chains was examined by studying their reaction kinetics. Furthermore, these modification agents were successfully applied to the synthesis of macromonomers for graft polymerization and various block copolymers, with, for example, AB‐type, star‐shaped, and H‐shaped architectures. © 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019, 57, 2396–2406
Self‐compassion and hope in the context of body image disturbance and distress in breast cancer survivors
Authors: Todorov Natasha , Sherman Kerry A. , Kilby Christopher J. ,   Breast Cancer Network Australia
Published: August 2019

AbstractObjectiveGreater hope and self‐compassion have individually been associated with lower psychological distress in women with breast cancer. Self‐compassion is also associated with lower body image distress in this population, yet it is unknown whether hope also has this association. This study aimed to investigate the extent to which hope accounts for body image distress and psychological distress in breast cancer survivors alone, and in direct comparison to self‐compassion.MethodA total of 195 women were recruited from the Breast Cancer Network Australia and completed a cross‐sectional online anonymous questionnaire containing self‐report measures of body image (Body Image Scale), self‐compassion (Self Compassion Scale‐SF), hope (State Hope Scale), psychological distress (depression, anxiety, stress; DASS), and demographic/medical questions.ResultsSelf‐compassion and hope were inversely correlated with all outcomes. Hierarchical linear regression analyses indicated that self‐compassion and hope uniquely explained variance in all outcomes with different magnitudes of strength. Comparison of standardised betas indicated (a) Body image distress—self‐compassion (Bstd = −.355) vs hope (Bstd = −.161); (b) Stress—self‐compassion (Bstd = −.562) vs hope (Bstd = −.287); (c) Depression—hope (Bstd = −.447) vs self‐compassion (Bstd = −.374); (d) Anxiety—hope (Bstd = −.406) vs self‐compassion (Bstd = −.249).ConclusionThe unique contribution of self‐compassion and hope in explaining body image distress and psychological distress suggests that combined, hope‐focused components of therapy may be suitable additions to the growing array of self‐compassion–based psychosocial interventions to address body image and psychological distress concerns of women with breast cancer.
Analysis of the process parameters affecting the bone burring process: An in‐vitro porcine study
Authors: Kusins Jonathan R. , Tutunea‐Fatan O. Remus , Athwal George S. , Ferreira Louis M. 
Published: August 2019

AbstractBackgroundA stable bone burring process, which avoids thermal osteonecrosis and minimizes harmful vibrations, is important for certain orthopedic surgical procedures, and especially relevant to robot‐operated bone burring systems.MethodsAn experimental characterization of the effects of several bone burring process parameters was performed. Burring parameters were evaluated by resultant bone temperature, tool vibration, and burring force.ResultsAn optimal combination of bone burring parameters produced minimums in both bone temperature (<40°C) and tool vibration (<4 g‐rms). A cylindrical burr, oriented normal to the specimen, resulted in significantly higher temperatures (50.8 ± 6.8°C) compared with a spherical burr (33.5 ± 4.3°C) (P = .008). Regardless of the parameters tested, burring forces were less than 10 N.ConclusionsThe recommended configuration, which minimized both bone temperature and vibrations experimentally, was a 6‐mm spherical burr at 15 000 rpm with a 2 mm/s feed rate.
Preparation and Characterization of n‐Nonadecane/CaCO3 Microencapsulated Phase Change Material for Thermal Energy Storage
Authors: Zhang Qingwen , Liu Chenzhen , Rao Zhonghao 
Published: August 2019

AbstractA novel microencapsuled thermal energy storage phase change material (MicroEPCM) based on n‐nonadecane core and CaCO3 shell were synthesized via a self‐assembly method. The chemical structure, surface morphology and thermal properties of the MicroEPCM were investigated by X‐ray diffractometer (XRD), Fourier‐transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and thermogravimetric analyzer (TGA), respectively. The effects of core/shell mass ratios, stirring speed, temperature and emulsifier concentration on the morphology and thermal properties of the MicroEPCM were investigated to confirm the most suitable CaCO3‐encapsulated n‐nonadecane reaction conditions. The results showed that the optimal spherical morphology and the highest latent heat were obtained when the stirring rate is 800 rpm, the temperature is 45 °C, the emulsifier concentration is 15 mmol/L and the core/shell mass ratio is 3:1. The latent heat and encapsulation rate of MicroEPCM as above‐mentioned are 134.83 J/g and 59.68%, respectively. The thermal conductivity of MicroEPCM is improved up to 3.56 times than that of prinstine n‐nonadecane. The MicroEPCM did not leak after being heated at 80 °C for 20 h, which proves that the CaCO3 shell is compact. The MicroEPCM present a good thermal stability after 200 thermal cycling. The MicroEPCM also has been proved to maintain high mechanical strength.
Molybdenum Nitrides, Carbides and Phosphides as Highly Efficient Catalysts for the (hydro)Deoxygenation Reaction
Authors: Akhmetzyanova Uliana , Tišler Zdeněk , Sharkov Nikita , Skuhrovcová Lenka , Pelíšková Lenka , Kikhtyanin Oleg , Mäki‐Arvela Päivi , Opanasenko Maksym , Peurla Markus , Murzin Dmitry Yu. 
Published: August 2019

AbstractTransition metal nitrides, carbides and phosphides have the potential to replace the expensive and hazardous catalysts typically used for the conversion of fatty acids. However, there has been little research on the influence of treatment conditions and precursor nature on the properties of such catalytic systems. To better understand these dependencies, we synthesized a number of Mo catalysts by temperature‐programmed reduction (700‐900 °C; CH4/N2, N2/H2) using ammonium heptamolybdate, diammonium phosphate and hexamethylenetetramine (HMT) as Mo, C, N and P sources. The presence of HMT in the precursor mixtures ensured the synthesis of pure phase Mo2C, Mo2N and MoP. Catalytic activity in the (hydro)deoxygenation of stearic acid (240 min; 360 °C; 50 bar of H2) decreased in the following order: Mo2C>Mo2N>MoP. However, all of the studied Mo‐based catalysts showed good deoxygenation efficiency and, thus, represent excellent alternatives to traditional noble and sulfur‐containing catalysts.
Uranyl Coordination Compounds with Alkaline Earth Metals and Crotonate Ligands
Authors: Savchenkov Anton V. , Pirozhkov Pavel A. , Vologzhanina Anna V. , Zubavichus Yan V. , Dorovatovskii Pavel V. , Pushkin Denis V. , Serezhkina Larisa B. 
Published: August 2019

AbstractCrystal structures of three new uranyl compounds were solved using single crystal X‐ray diffraction and studied using FTIR spectroscopy. Although the syntheses conditions were very similar differing only in the alkaline earth metal (Mg, Ca or Sr), the resulting structures are different, containing, respectively, mono‐, tri‐ and hexanuclear metal‐containing building units. This fact proves the profound crystal‐chemical role of secondary metal atoms on the formation of crystal structures. Parameters of alkaline earth metal cations in the three newly synthesized compounds as well as in the earlier reported Ba‐containing analog are discussed in detail using Voronoi–Dirichlet polyhedra and the method of intersecting spheres. Differences in packing of building units in the four mentioned compounds, as well as inter‐ and intramolecular noncovalent interactions in their structures are reported. The results of analysis are consistent with the stereoatomic model of crystal structures.
Quercetin‐3‐Oleate Contributes to Skin Wound Healing Targeting FFA1/GPR40
Authors: Carullo Gabriele , Governa Paolo , Leo Antonio , Gallelli Luca , Citraro Rita , Cione Erika , Caroleo Maria Cristina , Biagi Marco , Aiello Francesca , Manetti Fabrizio 
Published: August 2019

AbstractThe hybrid molecule Quercetin‐3‐oleate (AV2), accommodates within the binding pocket for allosteric full GPR40 agonists. AV2 endorses skin wound healing acting as a promoter of keratinocytes proliferation and overcomes immunosuppressive conditions in vitro. AV2 stimulated HaCaT wound healing by 51% compared to the untreated control, at the concentration of 1 μM with slight TGF‐β production and MMP‐9 release. Pretreatment with the known GPR40 antagonist DC260126 abolished its wound healing power. Docking simulations suggested that both molecules share the same binding site.
Persistent impact of housing loss on cognitive decline after the 2011 Great East Japan earthquake and tsunami: Evidence from a 6‐year longitudinal study
Authors: Hikichi Hiroyuki , Aida Jun , Kondo Katsunori , Kawachi Ichiro 
Published: August 2019

AbstractIntroductionWe previously established that housing loss and residential dislocation in the 2011 Japan earthquake and tsunami was a risk factor for cognitive decline among older survivors. The present study extends the follow‐up of survivors out to 6 years.MethodsThe baseline for our natural experiment was established in a survey of older community‐dwelling adults who lived 80 km west of the epicenter 7 months before the earthquake and tsunami. Two follow‐up surveys were conducted approximately 2.5 years and 5.5 years after the disaster to ascertain the housing status and cognitive decline from 2810 older individuals (follow‐up rate through three surveys: 68.4%).ResultsThe experience of housing loss was persistently associated with cognitive disability (coefficient = 0.14, 95% confidence interval: 0.04 to 0.23).DiscussionExperiences of housing loss continued to be significantly associated with cognitive disability even six years after the disaster.
Two Ethical Ideals in Spinoza'sEthics: The Free Man and The Wise Man
Authors: SOYARSLAN SANEM 
Published: August 2019

AbstractAccording to Steven Nadler's novel interpretation of Spinoza's much discussed ‘free man’, the free man is not an unattainable ideal. On this reading, the free man represents an ideal condition not because he is passionless, as has often been claimed, but because even though he experiences passions, he ‘never lets those passions determine his actions’. In this paper, I argue that Nadler's interpretation is incorrect in taking the model of the free man to be an attainable ideal within our reach. Furthermore, I show that Spinoza's moral philosophy has room for another ideal yet attainable condition, which is represented by the wise man. On my reading, becoming a wise man consists not in surmounting human bondage, but in understanding ourselves as finite expressions of God's power and, thereby, coming to terms with the ineliminability of bondage for us due to our very human or modal condition in the Spinozistic universe.
On case loss and svarabhakti vowels: the sociolinguistic typology and geolinguistics of simplification in North Germanic
Authors: Blaxter Tam T. , Trudgill Peter 
Published: August 2019

AbstractWork in sociolinguistic typology and creole studies has established the theory that intensive language contact involving second language acquisition by adults tends to lead to grammatical simplification. This theory is built on many anecdotal case studies, including developments in the history of Continental North Germanic associated with contact with Middle Low German. In this paper, we assess the theory by examining two changes in the history of Norwegian: the loss of coda /Cr/ clusters and the loss of prepositional genitives. If the theory is correct, these changes should have been innovated in centers of contact with Middle Low German. We find that both changes in fact spread into southeastern Norwegian from Swedish. Since contact with Low German also took place in Sweden and Denmark, this is consistent with the theory. It opens questions for future research about the role of dialect contact in simplificatory change in North Germanic.
Multiplayer Games: Multimodal Features That Support Friendships of Students With Autism Spectrum Disorder
Authors: Stone Bessie G. , Mills Kathy A. , Saggers Beth 
Published: August 2019

AbstractThere is an absence of research into online friendships and video gaming activities of students with autism spectrum disorder (ASD). In this article we describe how friendships of students with ASD were developed in an online multiplayer context using the popular sandbox game, Minecraft. Multimodal analysis of the data demonstrated that online multiplayer gaming supported students’ use of speech to engage in conversations about their friendships, and to share gaming experiences with their offline and online friends. Online gaming enabled students to visually gather information about their friends’ online status and activities, and to engage in the creative and adventurous use of virtual images and material representations with friends. Despite the benefits for friendships, students with ASD experienced difficulties in friendships in multimodal ways. Notably, students engaged in verbal disagreements about video gaming discourses, sought out activities associated with the themes of death and damage using written text, and tended to dominate shared creations of virtual images and their representation. The findings have implications to better support the friendships of students through inclusive literacy practices online.