bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving the Stability of Metal Halide Perovskite Quantum Dots by Encapsulation
Authors: Lv Wenzhen , Li Ling , Xu Mingchuan , Hong Junxian , Tang Xingxing , Xu Ligang , Wu Yinghong , Zhu Rui , Chen Runfeng , Huang Wei 
Published: May 2019

AbstractMetal halide perovskite quantum dots (PQDs), with excellent optical properties and spectacular characteristics of direct and tunable bandgaps, strong light‐absorption coefficients, high defect tolerance, and low nonradiative recombination rates, are highly attractive for modern optoelectronic devices. However, the stability issue of PQDs remains a critical challenge of this newly emerged material despite the recent rapid progress. Here, the encapsulation strategies to improve the stability of PQDs are comprehensively reviewed. A special emphasis is put on the effects of encapsulation, ranging from the improvement of chemical stability, to the inhibition of light‐induced decomposition, to the enhancement of thermal stability. Particular attention is devoted to summarizing the encapsulation approaches, including the sol–gel method, the template method, physical blending, and microencapsulation. The selection principles of encapsulation materials, including the rigid lattice or porous structure of inorganic compounds, the low penetration rate of oxygen or water, as well as the swelling–deswelling process of polymers, are addressed systematically. Special interest is put on the applications of the encapsulated PQDs with improved stability in white light‐emitting diodes, lasers, and biological applications. Finally, the main challenges in encapsulating PQDs and further investigation directions are discussed for future research to promote the development of stable metal halide perovskite materials.
Homozygous Type IX collagen variants (COL9A1, COL9A2, and COL9A3) causing recessive Stickler syndrome—Expanding the phenotype
Authors: Nixon Thomas R. W. , Alexander Philip , Richards Allan , McNinch Annie , Bearcroft Philip W. P. , Cobben Jan , Snead Martin P. 
Published: May 2019

AbstractStickler syndrome (SS) is characterized by ophthalmic, articular, orofacial, and auditory manifestations. SS is usually autosomal dominantly inherited with variants in COL2A1 or COL11A1. Recessive forms are rare but have been described with homozygous variants in COL9A1, COL9A2, and COL9A3 and compound heterozygous COL11A1 variants. This article expands phenotypic descriptions in recessive SS due to variants in genes encoding Type IX collagen. Clinical features were assessed in four families. Genomic DNA samples derived from venous blood were collected from family members. Six affected patients were identified from four pedigrees with variants in COL9A1 (one family, one patient), COL9A2 (two families, three patients), and COL9A3 (one family, two patients). Three variants were novel. All patients were highly myopic with congenital megalophthalmos and abnormal, hypoplastic vitreous gel, and all had sensorineural hearing loss. One patient had severe arthropathy. Congenital megalophthalmos and myopia are common to dominant and recessive forms of SS. Sensorineural hearing loss is more common and severe in recessive SS. We suggest that COL9A1, COL9A2, and COL9A3 be added to genetic screening panels for patients with congenital hearing loss. Although recessive SS is rare, early diagnosis would have a high impact for children with potentially dual sensory impairment, as well as identifying risk to future children.
Anisotropic Superfluidity in a Weakly Interacting Condensate of Quasi‐2D Photons
Authors: Voronova Nina S. , Lozovik Yurii E. 
Published: May 2019

AbstractThe anisotropic superfluidity in a weakly interacting two‐dimensional Bose gas of photons in a dye‐filled optical microcavity is investigated, taking into account the dependence of the photon effective mass on the in‐plane coordinate. With the use of the generalized Gross–Pitaevskii equation and the Bogoliubov approach, it is shown that the modulation of the microcavity width leads to an effective periodic potential and the periodicity of the condensate wave function, and both the condensate energy and the spectrum of elementary excitations depend on the direction of motion. The anisotropic character of the dynamical and superfluid properties, such as helicity modulus, superfluid density, and sound velocity, as well as experimentally observable manifestations of their anisotropy are described.
Polyhalogen‐ und Polyinterhalogen‐Anionen von Fluor bis Iod
Authors: Sonnenberg Karsten , Mann Lisa , Redeker Frenio A. , Schmidt Benjamin , Riedel Sebastian 
Published: May 2019

AbstractDieser Aufsatz widmet sich dem wachsenden Gebiet der Polyhalogen‐Chemie und insbesondere den Polyhalogen‐Anionen (Polyhalogenide). Neben einem historischen Abriss werden aktuelle Entwicklungen in der Synthese von Polyfluoriden, ‐chloriden, ‐bromiden und ‐interhalogeniden erläutert. Die Strukturvielfalt der Polyhalogenide hat in den letzten zehn Jahren drastisch zugenommen, besonders für Polychloride und ‐bromide, die gewöhnlich mittels Einkristallröntgenbeugung, Raman‐Spektroskopie sowie quantenchemischer Rechnungen charakterisiert werden. Polyfluoride wurden sowohl mit modernsten quantenchemischen Methoden als auch mittels spektroskopischer Verfahren in Edelgas‐Matrixisolationsexperimenten bei 4 K untersucht. Die Bindungssituation in Polyhalogeniden wird diskutiert, und der letzte Abschnitt dieses Aufsatzes widmet sich der Anwendung von Polyhalogeniden in Halogenierungsreaktionen und der Elektrochemie sowie als reaktive ionische Flüssigkeiten und zeigt vielversprechende Perspektiven für die Zukunft des Gebiets der Polyhalogen‐Chemie auf.
Phosphine‐Catalyzed Activation of Alkylidenecyclopropanes: Rearrangement to Form Polysubstituted Furans and Dienones
Authors: He Xin , Tang Yuhai , Wang Yongzhuang , Chen Jian‐Bo , Xu Silong , Dou Jianwei , Li Yang 
Published: May 2019

AbstractWe report a phosphine‐catalyzed ring opening of electron‐deficient alkylidenecyclopropanes (ACPs) to generate allylic phosphonium zwitterions that resemble the well‐studied phosphine‐allene adducts but exhibit distinct properties. The potent reactivity of these intermediates has been demonstrated in three types of substrate‐controlled phosphine‐catalyzed rearrangements of alkylidenecyclopropylketones, which chemoselectively afford tri‐ and tetrasubstituted furans, and trisubstituted dienones in good yields.
A Giant Dy76 Cluster: A Fused Bi‐Nanopillar Structural Model for Lanthanide Clusters
Authors: Li Xiao‐Yu , Su Hai‐Feng , Li Quan‐Wen , Feng Rui , Bai Hui‐Yun , Chen Hua‐Yu , Xu Jian , Bu Xian‐He 
Published: May 2019

AbstractAlthough great achievements have been made in the synthesis of giant lanthanide clusters, novel structural models are still scarce. Herein, we report a giant lanthanide cluster Dy76, constructed from [Dy3(μ3‐OH)4] and [Dy5(μ4‐O)(μ3‐OH)8] building blocks. As the largest known Dy cluster, the structure of Dy76 can be seen as arising from the fusion of two Dy48 clusters; these clusters can be isolated under various synthetic conditions and were characterized by single‐crystal X‐ray diffraction. This new, fused structural model of the pillar motif has not been found in Ln clusters. Furthermore, the successful conversion of Dy76 back into Dy48 in a retrosynthetic manner supports the proposed fusion formation mechanism of Dy76. Electrospray ionization mass spectrometry (ESI‐MS) analysis suggests that the metal cluster skeleton of Dy76 shows good stability in various solvents. This work not only reveals a new structural type of Ln clusters but also provides insight into the novel fusion assembly process.
A Fused Hexacyclic Ring System: Diastereoselective Polycyclization of 2,4‐Dienals through an Interrupted iso‐Nazarov Reaction
Authors: Marques Anne‐Sophie , Duhail Thibaut , Marrot Jérome , Chataigner Isabelle , Coeffard Vincent , Vincent Guillaume , Moreau Xavier 
Published: May 2019

AbstractWe report an unprecedented domino polycyclization from readily available 2,4‐dienals and cyclic α,β‐unsaturated imines that is initiated by an iso‐Nazarov reaction. This Brønsted acid promoted reaction enables the concomitant formation of four bonds, three cycles, and four contiguous stereogenic centers to yield elaborated structures in a single operation. A range of fused hexacyclic molecules is obtained in a highly diastereoselective manner.
Use of rhamnolipid in micellar‐enhanced ultrafiltration for simultaneous removal of Cd+2 and crystal violet from aqueous solution
Authors: Verma Satya Pal , Sarkar Biswajit 
Published: May 2019

AbstractThe application of rhamnolipid (RHL) in micellar‐enhanced ultrafiltration (MEUF) was investigated to remove both cadmium ion (Cd+2) and crystal violet (CV) simultaneously from aqueous solution. The effects of the membrane pore size, feed conditions, and operating conditions on solute removal efficiency and permeate flux were studied. Response surface methodology (RSM) was used to obtain the optimal feed conditions. Eigenvalue analysis was performed to evaluate the nature of optimal condition. Critical micelle concentration and aggregate size of RHL in the presence of Cd+2 and CV were determined. Ultrafiltration data were used to estimate the partition coefficient, distribution coefficient and relative affinity of the pollutants, and loading capacity of RHL vesicles. Compared with chemical surfactants, the use of RHL in MEUF process with larger membrane pore size performed better in terms of process throughput. About (84 ± 1)% of initial RHL was recovered from retentate stream using acid precipitation technique, at the optimal recovery condition obtained through RSM. The experimental results obtained using optimal feed condition and RHL recovery condition matched well with the predicted results. Reclaimed RHL was successfully used two times in MEUF with rejection efficiency of 96.7% for Cd+2 and 97.8% for CV, thus, significantly lower the cost of the MEUF process.
Lubrication behaviors of PVA‐casted LSPEEK hydrogels in artificial cartilage repair
Authors: Zhou Huangjie , Xiong Dangsheng , Tong Wei , Shi Zhibing , Xiong Xiaoya 
Published: May 2019

ABSTRACTPoly(ether‐ether‐ketone) (PEEK) is a known bio‐implant material due to its excellent mechanical properties. However, the challenging issue of high friction coefficient limits the PEEK applications. In this article, double‐layered hydrogel material was obtained by laser processing, surface sulfonation, and poly(vinyl alcohol) (PVA) casting. Characterizations of FT‐IR, XRD, SEM, and 3D‐morphology demonstrate that PVA‐LSPEEK hydrogel was achieved successfully. PVA‐LSPEEK exhibits an extremely smooth surface with a roughness of 0.079 μm. And this hydrogel presents an excellent mechanical adhesion to PEEK substrate, forming a soft‐hard structure. Tribological properties of PVA‐LSPEEK are improved drastically when compared to the PEEK substrate. This innovative hydrogel material provides a potential application in articular cartilage defect repair. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47944.
Ultrastructural Characterization of Stem Cell‐Derived Replacement Vestibular Hair Cells Within Ototoxin‐Damaged Rat Utricle Explants
Authors: Werner Mimmi , Van De Water Thomas R. , Stenlund Hans , Berggren Diana 
Published: May 2019

ABSTRACTThe auditory apparatus of the inner ear does not show turnover of sensory hair cells (HCs) in adult mammals; in contrast, there are many observations supporting low‐level turnover of vestibular HCs within the balance organs of mammalian inner ears. This low‐level renewal of vestibular HCs exists during normal conditions and it is further enhanced after trauma‐induced loss of these HCs. The main process for renewal of HCs within mammalian vestibular epithelia is a conversion/transdifferentiation of existing supporting cells (SCs) into replacement HCs.In earlier studies using long‐term organ cultures of postnatal rat macula utriculi, HC loss induced by gentamicin resulted in an initial substantial decline in HC density followed by a significant increase in the proportion of HCs to SCs indicating the production of replacement HCs. In the present study, using the same model of ototoxic damage to study renewal of vestibular HCs, we focus on the ultrastructural characteristics of SCs undergoing transdifferentiation into new HCs. Our objective was to search for morphological signs of SC plasticity during this process. In the utricular epithelia, we observed immature HCs, which appear to be SCs transdifferentiating into HCs. These bridge SCs have unique morphological features characterized by formation of foot processes, basal accumulation of mitochondria, and an increased amount of connections with nearby SCs. No gap junctions were observed on these transitional cells. The tight junction seals were morphologically intact in both control and gentamicin‐exposed explants. Anat Rec, 303:506–515, 2020. © 2019 The Authors. The Anatomical Record published by Wiley Periodicals, Inc. on behalf of American Association of Anatomists.
Solvent Dependent Spin‐Crossover and Photomagnetic Properties in an Imidazolylimine FeII Complex
Authors: Archer Rosanna J. , Scott Hayley S. , Polson Matthew I.J. , Mathonière Corine , Rouzières Mathieu , Clérac Rodolphe , Kruger Paul E. 
Published: May 2019

AbstractThe synthesis and physico‐chemical characterization of an FeII complex [Fe(L1)3](ClO4)2⋅CH3CN⋅0.5H2O, 1, incorporating a bidentate imidazolylimine‐based ligand are reported. Complex 1 crystallises as the mer‐isomer and the crystal lattice is replete with hydrogen bonding interactions between ClO4− anions, solvent molecules and imidazole N‐H groups. Variable‐temperature structural, magnetic, photomagnetic and optical reflectivity techniques have been deployed to fully characterise the spin‐crossover (SCO) behaviour in 1 along with its desolvated phase, 1⋅desolv. Variable‐temperature (1.8–300 K) magnetic‐susceptibility measurements reveal a broad two‐step full SCO for 1 (T1/2=158 and 184 K) and photomagnetic experiments at 10 K under white‐light irradiation revealed complete photo‐induced SCO. 1⋅desolv displays considerably different magnetic behaviour with sharp single‐step SCO accompanied by a thermal hysteresis (T1/2↑=105 K, T1/2↓=95 K) in addition to full photo‐induced SCO at lower temperatures.
KMT2A histone methyltransferase contributes to colorectal cancer development by promoting cathepsin Z transcriptional activation
Authors: Fang Yang , Zhang Dan , Hu Tingting , Zhao Hongyan , Zhao Xuan , Lou Zhefeng , He Yongshan , Qin Wenzheng , Xia Jianfu , Zhang Xiaohua , Ye Le‐chi 
Published: May 2019

AbstractAccumulating evidence supports the notion that epigenetic modifiers are abnormal in carcinogenesis and have a fundamental role in cancer progression. Among these aberrant epigenetic modifiers, the function of histone methyltransferase KMT2A in somatic tumors is not well known. By analyzing KMT2A expression in patient tissues, we demonstrated that KMT2A was overexpressed in colorectal cancer tissues in comparison with adjacent normal tissues and its expression was positively correlated with cancer stages. In KMT2A‐knockdown HCT116 and DLD1 cells, cell invasion and migration were consequently suppressed. In addition, KMT2A depletion effectively suppressed cancer metastasis in vivo. Mechanistically, cathepsin Z (CTSZ) was demonstrated to be an important downstream gene of KMT2A. Further studies showed that p65 could recruit KMT2A on the promoter region of the downstream gene CTSZ and knockdown of p65 could reduce the KMT2A on the promoter of CTSZ. Finally, our present study revealed that KMT2A epigenetically promotes cancer progression by targeting CTSZ, which has specific functions in cancer invasion and metastasis.
Efficient Chemoselective Reduction of N‐Oxides and Sulfoxides Using a Carbon‐Supported Molybdenum‐Dioxo Catalyst and Alcohol
Authors: Li Jiaqi , Liu Shengsi , Lohr Tracy L. , Marks Tobin J. 
Published: May 2019

AbstractThe chemoselective reduction of a wide range of N‐oxides and sulfoxides with alcohols is achieved using a carbon‐supported dioxo‐molybdenum (Mo@C) catalyst. Of the 10 alcohols screened, benzyl alcohol exhibits the highest reduction efficiency. A variety of N‐oxide and both aromatic and aliphatic sulfoxide substrates bearing halogens as well as additional reducible functionalities are efficiently and chemoselectively reduced with benzyl alcohol. Chemoselective N‐oxide reduction is effected even in the presence of potentially competing sulfoxide moieties. In addition, the Mo@C catalyst is air‐ and moisture‐stable, and is easily separated from the reaction mixture and then re‐subjected to reaction conditions over multiple cycles without significant reactivity or selectivity degradation. The high stability and recyclability of the catalyst, paired with its low toxicity and use of earth‐abundant elements makes it an environmentally friendly catalytic system.
Electrodeposition Conditions Effect Sb2Se3 Thin‐Film Properties
Authors: Costa Magno Barcelos , Lucas Francisco W. S. , Mascaro Lucia Helena 
Published: May 2019

AbstractSb2Se3 is presented as a promising light absorber material of low‐cost and good photoelectrocatalytic activity. Among the different synthetic methods for this semiconductor, electrodeposition has gained attention. In this context, a study of the electrodeposition parameters is an important aspect for obtaining films with optimized photocatalytic characteristics. Thus, in this work, we studied the effect of precursor concentration, the total charge of deposition, the type of supporting electrolyte, bath temperature, and the deposition potential on obtaining antimony selenide thin films electrochemically and on the morphological, structural, and optoelectronic properties of these films. One of the most interesting observations was the huge impact of these parameters on the morphology. The Se‐rich films showed a tendency to have a rod‐like morphology and relatively better stability to photocorrosion. The thickness of the film is another parameter that hugely affected the photocatalytic properties. From the evaluation of the photocurrent values presented by the films, the optimized electrodeposition parameters were found.
Hydrogenolysis of Dinuclear PCNR Ligated PdII μ‐Hydroxides and Their Mononuclear PdII Hydroxide Analogues
Authors: Bailey Wilson D. , Phearman Alexander S. , Luconi Lapo , Rossin Andrea , Yakhvarov Dmitry G. , D'Accolti Lucia , Flowers Sarah E. , Kaminsky Werner , Kemp Richard A. , Giambastiani Giuliano , Goldberg Karen I. 
Published: May 2019

AbstractThe hydrogenolysis of mono‐ and dinuclear PdII hydroxides was investigated both experimentally and computationally. It was found that the dinuclear μ‐hydroxide complexes {[(PCNR)Pd]2(μ‐OH)}(OTf) (PCNH=1‐[3‐[(di‐tert‐butylphosphino)methyl]phenyl]‐1H‐pyrazole; PCNMe=1‐[3‐[(di‐tert‐butylphosphino)methyl]phenyl]‐5‐methyl‐1H‐pyrazole) react with H2 to form the analogous dinuclear hydride species {[(PCNR)Pd]2(μ‐H)}(OTf). The dinuclear μ‐hydride complexes were fully characterized, and are rare examples of structurally characterized unsupported singly bridged μ‐H PdII dimers. The {[(PCNMe)Pd]2(μ‐OH)}(OTf) hydrogenolysis mechanism was investigated through experiments and computations. The hydrogenolysis of the mononuclear complex (PCNH)Pd‐OH resulted in a mixed ligand dinuclear species [(PCNH)Pd](μ‐H)[(PCC)Pd] (PCC=a dianionic version of PCNH bound through phosphorus P, aryl C, and pyrazole C atoms) generated from initial ligand “rollover” C−H activation. Further exposure to H2 yields the bisphosphine Pd0 complex Pd[(H)PCNH]2. When the ligand was protected at the pyrazole 5‐position in the (PCNMe)Pd−OH complex, no hydride formed under the same conditions; the reaction proceeded directly to the bisphosphine Pd0 complex Pd[(H)PCNMe]2. Reaction mechanisms for the hydrogenolysis of the monomeric and dimeric hydroxides are proposed.
A Structural and Functional Model for the Tris‐Histidine Motif in Cysteine Dioxygenase
Authors: Anandababu Karunanithi , Ramasubramanian Ramamoorthy , Wadepohl Hubert , Comba Peter , Johnee Britto Neethinathan , Jaccob Madhavan , Mayilmurugan Ramasamy 
Published: May 2019

AbstractThe iron(II) complexes [Fe(L)(MeCN)3](SO3CF3)2 (L are two derivatives of tris(2‐pyridyl)‐based ligands) have been synthesized as models for cysteine dioxygenase (CDO). The molecular structure of one of the complexes exhibits octahedral coordination geometry and the Fe−Npy bond lengths [1.953(4)–1.972(4) Å] are similar to those in the Cys‐bound FeII‐CDO; Fe−NHis: 1.893–2.199 Å. The iron(II) centers of the model complexes exhibit relatively high FeIII/II redox potentials (E1/2=0.988–1.380 V vs. ferrocene/ferrocenium electrode, Fc/Fc+), within the range for O2 activation and typical for the corresponding nonheme iron enzymes. The reaction of in situ generated [Fe(L)(MeCN)(SPh)]+ with excess O2 in acetonitrile (MeCN) yields selectively the doubly oxygenated phenylsulfinic acid product. Isotopic labeling studies using 18O2 confirm the incorporation of both oxygen atoms of O2 into the product. Kinetic and preliminary DFT studies reveal the involvement of an FeIII peroxido intermediate with a rhombic S=
FeIII center (687–696 nm; g≈2.46–2.48, 2.13–2.15, 1.92–1.94), similar to the spectroscopic signature of the low‐spin Cys‐bound FeIIICDO (650 nm, g≈2.47, 2.29, 1.90). The proposed FeIII peroxido intermediates have been trapped, and the O−O stretching frequencies are in the expected range (approximately 920 and 820 cm−1 for the alkyl‐ and hydroperoxido species, respectively). The model complexes have a structure similar to that of the enzyme and structural aspects as well as the reactivity are discussed.
Hydrogen‐Bond Cyclization Programming of Ultrasensitive Esters and Its Application in Gene Delivery
Authors: Li Shengran , Yan Xinxin , Qu Yangchun , Wang Wenliang , Chen Binggang , Ma Xiaojing , Liu Sanrong , Yu Xifei 
Published: May 2019

AbstractThe ester bond as a universal linker has recently been applied in gene delivery systems owing to its efficient gene release by electrostatic repulsion after its cleavage. However, the ester bond is nonlabile and is difficult to cleave in cells. This work reports a method in which a secondary amine was introduced to the β‐position of the ester bond to generate a hydrogen‐bond cyclization (HBC) structure that can make the ester bond hydrolysis ultrafast. A series of molecules comprising ultrasensitive esters that can be activated by H2O2 were synthesized, and it was found that those able to form an HBC structure showed complete ester hydrolysis within 5 h in both water and phosphate‐buffered saline solution, which was several times faster than other methods reported. Then, a series of amphiphilic poly(amidoamine) dendrimers were constructed, comprising the ultrasensitive ester groups for gene delivery; it was found that they could effectively release genes under quite a low concentration of H2O2 (<200 μm) and transport them into the nucleus within 2 h in Hela cells with high safety. Their gene transfection efficiencies were higher than that of PEI25k. The results demonstrated that the hydrogen‐bond‐induced ultrasensitive esters could be powerfully applied to construct gene delivery systems.