bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enlarging Trauma-Induced Superficial Temporal Artery Pseudoaneurysm
Authors: Bender Melinda , Yesenko Sandra , Sakarwala Abizer , Tan Carmela D. , Joseph Douglas 
Published: March 2018

Introduction Pseudoaneurysm of the superficial temporal artery is rare and most often the result of blunt trauma to the head. Thomas Bartholin first observed and reported on this phenomenon in 1740. Case Report Presented is the case of an 18-year-old man referred for the evaluation of a pulsatile mass over the left temple that developed after an altercation occurring in the preceding 2 months. Methods Duplex ultrasound examination was performed with the use of a Philips IU22 (Bothell, WA) with a 17–5 MHz linear transducer. Results Fusiform dilation of the frontal branch of the superficial temporal artery was noted, measuring 0.6 × 0.8 cm and containing echogenic material. The proximal segment of the artery measured 0.2 × 0.2 cm. A follow-up scan was performed 6 weeks later demonstrating enlargement of the aneurysm to 0.6 × 1.2 cm with additional homogeneous thrombus. The aneurysm was resected, followed by suture ligation of the inflow and outflow arteries. Pathologic description was consistent with a dilated segment of artery filled with organizing granulating tissue and focal areas of thrombosis. The wall of the aneurysm consisted of fibrous tissue only, with no evidence of a muscular layer. No evidence of inflammatory infiltrate or giant cells was identified. Conclusions Aneurysms may be saccular or fusiform and may be true or false. Aneurysmal dilation is identified when a vessel measures 1.5 times the diameter of the proximal segment. A true aneurysm will involve all layers of the vessel wall, whereas a false aneurysm (pseudoaneurysm) is identified when less than all layers of the vessel wall are involved. Aneurysms resulting from a single traumatic event, such as the one described in the present case report, are most often pseudoaneurysms. The superficial temporal artery and its branches are readily and accurately evaluated and characterized by duplex ultrasound.
Comparison of the efficacy and safety of non-steroidal anti-inflammatory drugs for patients with primary dysmenorrhea: A network meta-analysis
Authors: Feng Xuan , Wang Xiaoyun 
Published: March 2018

Objective Non-steroidal anti-inflammatory drugs are used as first-line treatment of primary dysmenorrhea, but there has been no optimal clinical choice among non-steroidal anti-inflammatory drugs yet. The present study was to assess the relative benefits of different common non-steroidal anti-inflammatory drugs for primary dysmenorrhea patients with a network meta-analysis. Methods Randomized controlled trials were screened by our criteria and included in the network meta-analysis. Pain relief was considered as primary outcomes and adverse effect was supplied as a safety outcome, while additional rescue, assessment score, and pain intensity difference were secondary outcomes. All the indexes were evaluated with odds ratio or standardized mean difference. Surface under cumulative ranking curve result was used to calculate the ranking of each treatment. Results Totally, 72 randomized controlled trials of 5723 patients and 13 drugs were included in our study after screening. As for pain relief, all drugs except nimesulide, rofecoxib, and waldecoxib were superior to aspirin (odds ratio with 95% credible intervals, diclofenac: 0.28 (0.08, 0.86), flurbiprofen: 0.10 (0.03, 0.29), ibuprofen: 0.32 (0.14, 0.73), indomethacin: 0.21 (0.07, 0.58), ketoprofen: 0.25 (0.10, 0.64), mefenamic acid: 0.28 (0.09, 0.87), naproxen: 0.31 (0.15, 0.64), piroxicam: 0.15 (0.03, 0.59), and tiaprofenic acid: 0.17 (0.04, 0.63)). Aspirin also required additional rescue when compared with the majority of other drugs (flurbiprofen: 3.46 (1.15, 11.25), ibuprofen: 6.30 (2.08, 20.09), mefenamic acid: 7.32 (1.51, 37.71), naproxen: 2.66 (1.17, 6.55), and tiaprofenic acid: 9.58 (1.43, 94.63)). As for assessment of the whole treatment, ketoprofen, naproxen, rofecoxib, and ibuprofen got higher score significantly than placebo. In addition, ibuprofen performed better than placebo in pain intensity difference. Considering the safety, tiaprofenic acid and mefenamic acid were noticeable in low risk, and indomethacin revealed higher risk than any other drugs. According to the results of network analysis and surface under cumulative ranking curve, flurbiprofen was considered to be the best one among all the treatments in efficacy, and aspirin was worse than most of others. On the other hand, tiaprofenic acid and mefenamic acid were indicated as the safest drugs. Conclusion Considering the efficacy and safety, we recommended flurbiprofen and tiaprofenic acid as the optimal treatments for primary dysmenorrhea.
Severe Lumbar Disability Is Associated With Decreased Psoas Cross-Sectional Area in Degenerative Spondylolisthesis
Authors: Wagner Scott C. , Sebastian Arjun S. , McKenzie James C. , Butler Joseph S. , Kaye Ian D. , Morrissey Patrick B. , Vaccaro Alexander R. , Kepler Christopher K. 
Published: March 2018

Study Design: Retrospective cohort. Objectives: Alterations in lumbar paraspinal muscle cross-sectional area (CSA) may correlate with lumbar pathology. The purpose of this study was to compare paraspinal CSA in patients with degenerative spondylolisthesis and severe lumbar disability to those with mild or moderate lumbar disability, as determined by the Oswestry Disability Index (ODI). Methods: We retrospectively reviewed the medical records of 101 patients undergoing lumbar fusion for degenerative spondylolisthesis. Patients were divided into ODI score ≤40 (mild/moderate disability, MMD) and ODI score >40 (severe disability, SD) groups. The total CSA of the psoas and paraspinal muscles were measured on preoperative magnetic resonance imaging (MRI). Results: There were 37 patients in the SD group and 64 in the MMD group. Average age and body mass index were similar between groups. For the paraspinal muscles, we were unable to demonstrate any significant differences in total CSA between the groups. Psoas muscle CSA was significantly decreased in the SD group compared with the MMD group (1010.08 vs 1178.6 mm2, P = .041). Multivariate analysis found that psoas CSA in the upper quartile was significantly protective against severe disability ( P = .013). Conclusions: We found that patients with severe lumbar disability had no significant differences in posterior lumbar paraspinal CSA when compared with those with mild/moderate disability. However, severely disabled patients had significantly decreased psoas CSA, and larger psoas CSA was strongly protective against severe disability, suggestive of a potential association with psoas atrophy and worsening severity of lumbar pathology.
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS
Authors: An Ningfei , Khan Saira , Imgruet Molly K. , Gurbuxani Sandeep K. , Konecki Stephanie N. , Burgess Michael R. , McNerney Megan E. 
Published: March 2018

Key PointsCUX1 deficiency leads to transient clonal expansion followed by HSC depletion, anemia, and trilineage dysplasia. CUX1 transcriptionally regulates HSC quiescence, proliferation, and lineage specification.
Expansionism, Extremism, and Exceptionalism in Life
Authors: Walford Antonia , Kirk Donnacha 
Published: March 2018

AbstractThis article explores how taking physical cosmology and the entities that populate its fringes on their own terms might prompt anthropology to rethink what and how it thinks of life. Physical cosmologists work with inanimate matter that lies at the frontier of existential possibility, positing scales and concepts that seem to negate commonsense notions of life and nonlife. Although a common reaction in anthropology when faced with such infinite, nonhuman, and abstract landscapes is to try to crowbar “everyday life” back in, we argue that conceptual space needs to be made for another style of engagement between anthropology and physical cosmology. Taking the Boltzmann Brain as an example of life not only beyond the human but also beyond life as we know it, we start to flesh out a different sort of speculative, transdisciplinary endeavor.
Case Report: A rare case of prosthetic valve infective endocarditis caused by Aerococcus urinae
Authors: Adeel Muhammad , Tariq Saman , Akthar Hisham , Zaghloul Ahmed , Iorgoveanu Corina , Dehner Carina 
Published: March 2018

Infective endocarditis (IE) is a serious and life-threatening cardiac condition, most commonly caused by staphylococci, Streptococcus viridans, and enterococci. However, in special settings, IE can be caused by rare organisms. Here we present a case of IE caused by Aerococcus urinae in a 75-year-old man with a bioprosthetic aortic valve. Aerococcus urinae is a gram-positive, catalase-negative microorganism and is usually an isolate of complicated urinary tract infections in the elderly male population. Improvements in diagnostic testing including use of matrix-assisted laser desorption ionization– a time of flight mass spectrometry (MALDI-TOF MS) have played an important role in recognition of Aerococcus urinae.
Monocytes isolated by positive and negative magnetic sorting techniques show different molecular characteristics and immunophenotypic behaviour
Authors: Bhattacharjee Jashdeep , Das Barun , Mishra Alaknanda , Sahay Preeti , Upadhyay Pramod 
Published: March 2018

Background: Magnetic sorting of cells, based on microbead conjugated antibodies (Abs), employs positive as well as negative immunomagnetic separation methods, for isolation of a specific cell population. These microbeads are suggested to be nontoxic, biodegradable carriers conjugated to various antibodies. Isolation of cells through positive selection involves the attachment of antibody conjugated microbeads to the cells of interest, followed by their isolation in the presence of a strong magnetic field to obtain higher purity. Negative selection involves attachment of microbead conjugated antibodies to all other cell populations except the cells of interest, which remain untagged. In the present study, we compared the two methods for their effect on functional and immunophenotypic behavior of isolated CD14+ monocytes.Methods: Peripheral blood mononuclear cells (PBMCs) were isolated from blood collected from healthy volunteers by density gradient centrifugation. Human blood derived monocytes were isolated through positive selection and negative selection, making use of the appropriate monocyte isolation kit. Monocytes were then stimulated with lipopolysaccharide (LPS) and their activation and proliferation capacity were examined. The degradation or dissociation of cell-bound microbeads was also investigated.Results: We observed an impaired LPS sensitivity as well as poor activation and proliferation capacity upon stimulation by LPS in positively sorted CD14+ monocytes as compared to negatively sorted CD14+ monocytes. The attached microbeads did not degrade and remained attached to the cells even after 6 days of culture.Conclusions: Our results suggest that positively sorted CD14+ cells exhibit hampered functionality and may result in inaccurate analysis and observations in downstream applications. However, these cells can be used for immediate analytical procedures.
Predictive physiological anticipation preceding seemingly unpredictable stimuli: An update of Mossbridge et al’s meta-analysis
Authors: Duggan Michael , Tressoldi Patrizio 
Published: March 2018

Background: This is an update of the Mossbridge et al’s meta-analysis related to the physiological anticipation preceding seemingly unpredictable stimuli. The overall effect size observed was 0.21; 95% Confidence Intervals: 0.13 - 0.29 Methods: Eighteen new peer and non-peer reviewed studies completed from January 2008 to October 2017 were retrieved describing a total of 26 experiments and 34 associated effect sizes. Results: The overall weighted effect size, estimated with a frequentist multilevel random model, was: 0.29; 95% Confidence Intervals: 0.19-0.38; the overall weighted effect size, estimated with a multilevel Bayesian model, was: 0.29; 95% Credible Intervals: 0.18-0.39. Effect sizes of peer reviewed studies were slightly higher: 0.38; Confidence Intervals: 0.27-0.48 than non-peer reviewed articles: 0.22; Confidence Intervals: 0.05-0.39. The statistical estimation of the publication bias by using the Copas model suggest that the main findings are not contaminated by publication bias. Conclusions: In summary, with this update, the main findings reported in Mossbridge et al’s meta-analysis, are confirmed.
Profil Histologi Duodenum Berbagai Itik Lokal Di Kabupaten Semarang
Authors: Apriliyani Nur Indah , Djaelani Muhammad Anwar , Tana Silvana 
Published: March 2018

Local duck had been widely cultivated not only as a producer of eggs processed as salted egg but also there are cultivated as broiler ducks. The efforts to improve the productivity of ducks can be seen from the effectiveness of the process of absorption of nutrients in the duodenum, so the use of energy in the metabolic process can be optimized for adding mass and volume of the cell. This study aims to determine the duodenum profile of the histological structure covered the lumen diameter, villous height and number of goblet cells of Magelang ducks, Tegal ducks and Pengging ducks .This study used a completely randomized design (CRD) with three treatments (Magelang ducks, Tegal ducks and Pengging ducks) and 6 replications. The measured variable was the long intestine tenue, lumen diameter, villous height and number of goblet cells. Data were analyzed using analysis of variance (ANOVA) with a differentiation factor was the type of duck. The realdifferences data were analyzed using advanced test of Duncan at the level of 95%. The results showed long intestine tenue, lumen diameter and height of the villi were not significantly different at each Magelang ducks, Tegal ducks, Pengging ducks. The number of goblet cells in Magelang ducks and Tegal ducks showed significantly different, but not on Pengging Ducks. The conclusion of the study was the length of the intestine tenue, lumen diameter and height of villous had no real effect on three types of ducks. Keywords: Local ducks, duodenum, histological
Spirulina platensis Geitler sebagai Fikoremediator Logam Berat Pb Skala Laboratorium
Authors: Prambodo Muhammad Sindhunata , Hariyati Riche , Soeprobowati Tri Retnaningsih 
Published: March 2018

Industrial waste contributes the heavy metals pollution in the environment, especially in the water. One of the heavy metals that pollute the environment is lead (Pb). Lead is a substance that is harmful to organisms, especially humans, both adults and children. Solutions to tackle Pb pollution isby remediation process. Physical and chemical remediation methods usually costly and ineffective. One of the alternative methods which is used is the bioremediation uses microalgae or called as phycoremediation. One of microalgae which is used as agents of phycoremediation is Spirulina platensis Geitler because it’s easily cultured and it’s abundant in nature. This study aims to assess the population growth and the percentage reduction of Pb after inoculated with the use of Spirulina platensis Geitler. The method which is to cultivate S. platensis Geitler in brackish watermedia with a salinity of 15 ppt which have been added Pb with a concentration of 1 mg, 3 mg, and 5 mg for 8 days and observed the population and the percentage reduction of Pb heavy metals. Environmental factors such as temperature, salinity, pH, light intensity are conditioned to remain stable. After 8 days of research, study was able to reduce Pb. Each treatment has different concentrations decrease. Treatment Pb 1 mg of 0.949 into 0.603 mg / L; Pb 3 mg of 2.894 to 2.46 mg / L; and Pb 5 mg of 4.88 to 4.31 mg / L, with each percentage decline of 36%, 15% and 12%. The Pb 3 mg treatment has higher cell population (129.367 cell / ml) than control (106.600 cell/ml) while 1 mg and 5 mg treatment has 93.700 cell / ml and 93.500 cell / ml. Keywords: Spirulina platensis, phycoremediation, waste, lead.
Rasio Otot-Tulang Ekstremitas Posterior Ayam Pedaging Setelah Pemberian Teh Kombucha Dalam Air Minum
Authors: Kumala Amelia Setya Nur , Djaelani Muhammad Anwar , Yuniwarti Enny Yusuf Wachidah 
Published: March 2018

Kombucha tea beverage obtained by fermenting sweetened green tea for 12 days with Acetobacter xylinum and Saccharomyces which produce various kinds of organic acids, vitamins, and acts as a probiotic. Kombucha tea role as growth promoter is to enhance the metabolic processes in the digestive system of broiler, so that the nutrients can be absorbed and fulfilled properly for optimal growth and development. The research was conducted from September to October 2014 in the Laboratory of Biological Structure and Function, Diponegoro University. Posterior limb (femur-tibiotarsus) meat-bone ratio analysis was used to investigate the effects of kombucha tea on the productivity of broiler chicken. A total of 20 broiler chickens were randomly divided into 4 treatment concentrations ( 0%, 10%, 20%, and 40% of kombucha tea in drinking water) for 32 days. Statistical analysis using ANOVA at 0,05 significance level and Duncan’s Multiple Range Test showed significantly different results on body weight and water intake, while feed intake, meat weight, bone weight and meat-bone ratio showed no significant results. It can be concluded from this study that the decrease of broiler chicken body weight due to consumption of 40% kombucha tea concentration in drinking water, do not cause a decrease in posterior limb meat and bone weight so that the posterior limb meat-bone ratio were not significantly different. Key words: Kombucha tea, broiler chicken, posterior limb, meat-bone ratio.
Comparing Short-Memory Charts to Monitor the Traffic Intensity of Single Server Queues
Authors: Santos Marta , Morais Manuel Cabral , Pacheco António 
Published: March 2018

AbstractThis paper describes the application of simple quality control charts to monitor the traffic intensity of single server queues, a still uncommon use of what is arguably the most successful statistical process control tool. These charts play a vital role in the detection of increases in the traffic intensity of single server queueing systems such as the{M/G/1},{GI/M/1}and{GI/G/1}queues. The corresponding control statistics refer solely to a customer-arrival/departure epoch as opposed to several such epochs, thus they are termed short-memory charts. We compare the RL performance of those charts under three out-of-control scenarios referring to increases in the traffic intensity due to: a decrease in the service rate while the arrival rate remains unchanged; an increase in the arrival rate while the service rate is constant; an increase in the arrival rate accompanied by a proportional decrease in the service rate. These comparisons refer to a broad set of interarrival and service time distributions, namely exponential, Erlang, hyper-exponential, and hypo-exponential. Extensive results and striking illustrations are provided to give the quality control practitioner an idea of how these charts perform in practice.
Introduction to Stopping Time in Stochastic Finance Theory. Part II
Authors: Jaeger Peter 
Published: March 2018

Summary
We start proceeding with the stopping time theory in discrete time with the help of the Mizar system [1], [4]. We prove, that the expression for two stopping times k1 and k2 not always implies a stopping time (k1 + k2) (see Theorem 6 in this paper). If you want to get a stopping time, you have to cut the function e.g. (k1 + k2) ⋂ T (see [2, p. 283 Remark 6.14]). Next we introduce the stopping time in continuous time. We are focused on the intervals [0, r] where r ∈ ℝ. We prove, that for I = [0, r] or I = [0,+∞[ the set {A ⋂ I : A ∈ Borel-Sets} is a σ-algebra of I (see Definition 6 in this paper, and more general given in [3, p.12 1.8e]). The interval I can be considered as a timeline from now to some point in the future. This set is necessary to define our next lemma. We prove the existence of the σ-algebra of the τ -past, where τ is a stopping time (see Definition 11 in this paper and [6, p.187, Definition 9.19]). If τ1 and τ2 are stopping times with τ1 is smaller or equal than τ2 we can prove, that the σ-algebra of the τ1-past is a subset of the σ-algebra of the τ2-past (see Theorem 9 in this paper and [6, p.187 Lemma 9.21]). Suppose, that you want to use Lemma 9.21 with some events, that never occur, see as a comparison the paper [5] and the example for ST(1)={+∞} in the Summary. We don’t have the element +1 in our above-mentioned time intervals [0, r[ and [0,+1[. This is only possible if we construct a new σ-algebra on ℝ {−∞,+∞}. This construction is similar to the Borel-Sets and we call this σ-algebra extended Borel sets (see Definition 13 in this paper and [3, p. 21]). It can be proved, that {+∞} is an Element of extended Borel sets (see Theorem 21 in this paper). Now we use the interval [0,+∞] as a basis. We construct a σ-algebra on [0,+∞] similar to the book ([3, p. 12 18e]), see Definition 18 in this paper, and call it extended Borel subsets. We prove for stopping times with this given σ-algebra, that for τ1 and τ2 are stopping times with τ1 is smaller or equal than τ2 we have the σ-algebra of the τ1-past is a subset of the σ-algebra of the τ2-past, see Theorem 25 in this paper. It is obvious, that {+∞} 2 extended Borel subsets. In general, Lemma 9.21 is important for the proof of the Optional Sampling Theorem, see 10.11 Proof of (i) in [6, p. 203].
Dielectric Spectroscopy of Biomolecules up to 110 GHz
Authors: Laux Eva-Maria , Ermilova Elena , Pannwitz Daniel , Gibbons Jessica , Hölzel Ralph , Bier Frank F. 
Published: March 2018

Abstract
Radio-frequency fields in the GHz range are increasingly applied in biotechnology and medicine. In order to fully exploit both their potential and their risks detailed information about the dielectric properties of biological material is needed. For this purpose a measuring system is presented that allows the acquisition of complex dielectric spectra over 4 frequency decade up to 110 GHz. Routines for calibration and for data evaluation according to physicochemical interaction models have been developed. The frequency dependent permittivity and dielectric loss of some proteins and nucleic acids, the main classes of biomolecules, and of their sub-units have been determined. Dielectric spectra are presented for the amino acid alanine, the proteins lysozyme and haemoglobin, the nucleotides AMP and ATP, and for the plasmid pET-21, which has been produced by bacterial culture. Characterisation of a variety of biomolecules is envisaged, as is the application to studies on protein structure and function.
High Prevalence of Autoantibodies Against Monomeric C Reactive Protein (CRP) in Children with PFAPA Syndrome
Authors: Kraszewska-Głomba Barbara , Myszka Marta , Krajewska Magdalena , Szenborn Leszek 
Published: March 2018

Summary
PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome is an autoinflammatory disorder of unknown etiology. The aim of our study was to evaluate whether the presence of anti-mCRP autoantibodies (anti-mCRP) might possibly contribute to systemic inflammation during PFAPA flares. We carried out anti-mCRP testing (in-house ELISA) in a single-center, prospective cohort of 30 PFAPA patients (12 girls). We found a high prevalence (43.3%) of anti-mCRP antibodies in PFAPA patients during their febrile episodes, which implies the possible involvement of anti-mCRP antibodies in PFAPA pathogenesis.
The MacPherson-Henningsen Puzzle
Authors: Goldberg Victor 
Published: March 2018

AbstractIn the landmark case of MacPherson v. Buick, an automobilecompany was held liable for negligence notwithstanding a lack of privity withthe injured driver. Four decades later, in Henningsenv. Bloomfield Motors, the court held unconscionable the standard automobilecompany warranty which limited its responsibility to repair and replacement,even in a case involving physical injury. This suggests a puzzle: if it were soeasy for firms to contract out of liability, did MacPherson accomplish anything?