bluuebunny/crossref_metadata_2025_split huggingface dataset:
Key aspects of choosing antipyretic therapy in pediatric practice
Authors: Zakirova A. M. , Moroz T. B. , Faizullina R. A. , Samorodnova E. A. , Shayapova D. T. , Salmanidina D. R. , Kadriev A. G. , Rashitova E. L. , Khairullina L. A. , Kadriev D. A. 
Published: November 2024

Introduction. Currently, nonsteroidal anti-inflammatory drugs with anti-inflammatory, analgesic, and antipyretic effects are widely used in clinical practice.Aim. To obtain additional data on the efficacy and safety of paracetamol and ibuprofen in children with acute respiratory infections accompanied by fever.Materials and methods. A single-center (observational) study was conducted involving 32 children (5.2 ± 1.8 years) with fever due to acute respiratory disease. At temperatures above 38.5 °C, an antipyretic in the form of forte was prescribed in an age-specific dosage according to the instructions for a course of 3 days. Patients of the first group (n = 16) were prescribed paracetamol against the background of standard therapy for the underlying disease according to the nosology, children of the second group – ibuprofen forte in syrup without fragrances, dyes and flavor additives. The average daily temperature, frequency and duration of taking the study drugs, the development of adverse reactions, a score of satisfaction with parents/legal representatives of the use of antipyretics and quality of life were taken into account.Results. The result of therapy was clinical improvement: normalization of temperature (below 37.2 °C) over time with analysis of average daily values after 1, 4 hours, 1, 2, 3 days. The patients of both groups did not need to take antipyretics after 10 hours in 47.1% of cases, after 18 hours – in 53.8%. Noted the absence of adverse drug and allergic reactions and drug rejection by children, which confirms their safety. The average satisfaction rating of parents/legal representatives was 4.87 ± 0.23 (96.2% rated the effects of the studied drugs as “satisfied” and “completely satisfied”). The quality of life improved significantly with normalization of temperature by the end of the 3 days (1.92 ± 0.07).Discussion. The drugs ibuprofen and paracetamol are safe for use in pediatric practice if the dosage rules are followed and are approved for use by the World Health Organization, the FDA and other expert organizations. In addition, the emergence of new forms of release of these drugs is most important in pediatrics.Conclusions. The study conducted allows us to state the effectiveness of paracetamol and ibuprofen in the form of tablets and forte without fragrances, dyes and flavors, when taken in the correct dosage, which resulted in the relief of fever against the background of acute respiratory infections and an improvement in the quality of life.
The effect of antiseptic solutions on the accuracy in blood glucose measurement using a personal glucose meter
Authors: Vitebskaya A. V. , Telegina K. P. 
Published: November 2024

Introduction. Patients with diabetes mellitus perform blood glucose measurements daily using their personal glucose meters. The procedure of disinfecting the place of blood sampling with antiseptic solutions or washing hands with soap and drying them thoroughly is recommended to the patients to prevent infections. However, the effects of used antiseptics on the accuracy in blood glucose measurement using glucose meters have not been evaluated.Aim. To evaluate the effects of antiseptic solutions on the accuracy in blood glucose measurement using a personal glucose meter. Materials and methods. We mixed several drops of the control solution (CS) with low “L” or high “H” concentrations, which were developed for the Contour Plus glucose meter, and a drop of one of five antiseptic solutions: chlorhexidine bigluconate (Chlorhexidine), benzyl dimethyl[3-(myristoylamine)-propyl] ammonium chloride monohydrate (Miramistin), salts of fatty acids (liquid soap), ethyl alcohol, hydrogen peroxide. Thereafter, the blood glucose levels were measured with a glucose meter. The results obtained were compared with the reference range for the CS with appropriate concentration.Results. Chlorhexidine solution had no effect on the blood glucose measurements in the CS. Adding Miramistin solution (1/5 of the sample with CS “L” and “H”) and liquid soap (4/5 of the sample with CS “L” and 2/5 of the sample with CS “H”) resulted in underestimating blood glucose measurements. Alcohol solution had no effect on the blood glucose measurements in the CS “L”, but the glucometer failed to measure the blood glucose concentration in half of the cases, requiring the test strip to be replaced (“E11” error); when mixed with CS “H”, the measurements were overestimated in 2/5 of samples. Adding hydrogen peroxide solution (4/5 of the sample with CR “L” and “H”) resulted in overestimating the blood glucose measurements.Discussion. Getting fruit juice on the hands, applying hydroquinone-containing cosmetics to the skin affects the accuracy in glucose measurements. Correct use of alcohol-containing disinfectants does not affect results of the blood glucose measurement using a personal glucose meter.Conclusion. The results of the blood glucose measurement using a glucose meter can be significantly distorted if antiseptic gets into the sample. Traces of antiseptic should be removed before obtaining the sample that will be used to measure the blood glucose level with a glucose meter. Hydrogen peroxide should not be used as antiseptic solution when using a glucose meter.
Efficacy of bioregulatory therapy for acute respiratory infections in children
Authors: Malanicheva T. G. , Ziatdinova N. V. , Ashrafullina Ch. I. 
Published: November 2024

Introduction. Currently, much attention is paid to biregulatory therapy in the treatment of ARI, the goal of which is to improve the outcome of treatment by maintaining the body’s ability to autoregulate.Aim. To study the effectiveness and safety of bioregulatory therapy using the multicomponent homeopathic drug in children with acute respiratory infections.Materials and methods. 42 children with acute respiratory infections from 3 months to 7 years were examined. Main group: 22 children receiving, as part of complex therapy, the multicomponent homeopathic drug in the form of rectal suppositories as an antipyretic and anti-inflammatory agent. Comparison group: 20 children receiving the antipyretic and anti-inflammatory drug paracetamol. All patients were prescribed symptomatic therapy, which did not differ in the compared groups.Results. It was revealed that the administration of the multicomponent homeopathic drug leads to a more rapid decrease in temperature (in the main group 1.70 ± 0.14 day; in the comparison group – 3.78 ± 0.17 day, p < 0.05) against the background of the disappearance of myalgia, headache, relief of symptoms of discomfort and intoxication, as well as manifestations of the local inflammatory process (sore throat, hyperemia of the pharynx, nasal congestion, rhinorrhea, cough), which led to a reduction in the duration of the disease by 3.4 days and reducing the need for antibiotics by 3.3 times. No side effects from the use of the multicomponent homeopathic drug were identified.Discussion. The results of the study are comparable with the literature data. Thus, foreign authors have shown that the drug multicomponent homeopathic drug meets all the requirements for effective, but at the same time practically risk-free therapy for febrile anxiety, influenza infections, and pain.Conclusions. The prescription of the multicomponent homeopathic drug as part of the complex therapy of ARI in children leads to faster relief of all symptoms and a reduction in the duration of the disease than with the use of paracetamol, with a better safety profile.
Da'wah strategy of the Indonesian Ulema Council in broadcasting wasathiyah islamic values in Wonogiri
Authors: Syarifuddin Muhammad , Riyadi Agus , Ali Mukti 
Published: November 2024

Purpose – This study aims to determine the Indonesian Ulema Council (Majelis Ulama Indonesia, MUI) Da'wah Strategy in Wonogiri in broadcasting Wasathiyah Islamic values in Wonogiri as well as the supporting and inhibiting factors of the MUI Da'wah Strategy in Wonogiri.Method – This research is qualitative research, Data was collected by several data collection techniques: Observation, Interview, Documentation. The data analysis process is carried out throughout the research process, from planning and data collection to interpretation or interpretation of data or the content of data discussion in the field.Result – This research shows that there are three da'wah strategies used by MUI Wonogiri, namely: (1) Sentimental Da'wah Strategy (Al-Manhaj 'athifi), (2) Rational Da'wah Strategy (Al-Manhaj Al-Aqli), (3) Sensory Da'wah Strategy (Al-Manhaj Al-Hissi).Implication – The implications of this research are related to the importance of the da'wah movement of the Indonesian Ulema Council Wonogiri in strengthening the value of Wasathiyah IslamOriginality/Value – This study analyzes the views of the Da’i of the Wonogiri Indonesian Ulema Council on the understanding of wasathiyah Islam, and the activities of the da'wah movement in strengthening the understanding of Wasathiyah Islamic Values.***Tujuan - Penelitian ini bertujuan untuk mengetahui Strategi Dakwah MUI di Wonogiri dalam menyiarkan nilai-nilai Islam Wasathiyah di Wonogiri serta faktor-faktor pendukung dan penghambat Strategi Dakwah Majelis Ulama Indonesia (MUI) di WonogiriMetode - Penelitian ini merupakan penelitian kualitatif, Data dikumpulkan dengan beberapa teknik pengumpulan data: Pengamatan, Wawancara, Dokumentasi. Proses analisis data dilakukan selama proses penelitian, mulai dari perencanaan dan pengumpulan data hingga interpretasi atau interpretasi data atau isi pembahasan data di lapanganHasil - Penelitian ini menunjukkan bahwa: ada tiga strategi dakwah yang digunakan oleh MUI Wonogiri, yaitu: (1) Strategi Dakwah Sentimental (Al-Manhaj 'athifi), (2) Strategi Dakwah Rasional (Al-Manhaj Al-Aqli), (3) Strategi Dakwah Sensorik (Al-Manhaj Al-Hissi).Implikasi– Implikasi dari penelitian ini terkait pentingnya gerakan dakwah Majelis Ulama Indonesia Wonogiri dalam memperkuat nilai Islam Wasathiyah Orisinalitas/Nilai - Penelitian ini menganalisis pandangan Da’i Majelis Ulama Indonesia Wonogiri terhadap pemahaman Islam Wasathiyah , dan aktivitas gerakan dakwah dalam memperkuat pemahaman Nilai-Nilai Islam Wasathiyah
Ghana's water safety journey: A review of efforts toward a risked-based water quality management
Authors: Duku Godwin Armstrong , Appiah-Effah Eugene , Gyamfi Charles , Nyarko Kwabena Biritwum 
Published: November 2024

ABSTRACT

In 2015, Ghana launched the National Drinking Water Quality Management Framework (NDWQMF) to promote a risk-based approach to water quality through water safety plans (WSPs). This study uses a narrative review to synthesize WSP implementation progress in Ghana, identify gaps in practice, and provide recommendations for enhanced effectiveness and scale-up. Findings show limited uptake: only three of 88 urban water supply systems have adopted WSPs, while in the rural sector, the Community Water and Sanitation Agency has implemented WSPs in 177 of 1,022 small-town systems, and the safe water network in 46 systems. However, community-managed water systems overseen by local governments are yet to initiate WSPs. For those that have begun, significant documentation and implementation gaps are noted, including incomplete hazard listings, insufficient improvement plans, and absent standard operating procedures. To strengthen WSP implementation, this study emphasizes the need for robust regulatory mechanisms across urban and rural sectors, along with tailored guidelines and support structures to enable effective WSP adoption across diverse water systems.
Adapting the Germ Defence Web-Based Intervention to Improve Infection Prevention and Control in Care Homes: Interview Study Among Care Home Staff
Authors: Hall Alex , Aguilera-Muñoz Johanna , McGarrigle Lisa , Eost-Telling Charlotte , Denison-Day James , Cabral Christie , Willcox Merlin , Todd Chris 
Published: November 2024

Background
Infection prevention and control (IPC) is vital in care homes as it can reduce morbidity and mortality by 30%. Ensuring good IPC practice is a perennial challenge in the varied and complex context of care homes. Behavior change interventions delivered via digital technology may be effective in improving IPC among care home staff.

Objective
This study aimed to evaluate how an evidence-based, digital behavior change intervention called Germ Defence can be rapidly adapted to meet the needs of care homes.

Methods
This study applied the person-based approach, which emphasizes iterative approaches to optimizing interventions via individual user feedback. Phase 1 involved initial edits to the website by the research team to create Germ Defence for Care Homes (GDCH) version 1. Phase 2 consisted of stakeholder consultation on GDCH version 1 followed by edits to create GDCH version 2. The formal research (phases 3 and 4) involved individual think-aloud interviews with 21 staff members from management, care, and ancillary positions in 4 care homes providing real-time feedback as they worked through GDCH. Edits were made to create GDCH version 3 between phases 3 and 4. During the development of GDCH versions 2 and 3, it became clear that the intervention would need more fundamental changes beyond the pragmatic, incremental changes that would be possible within the scope of this study. Analysis was completed via a rapid, qualitative descriptive approach to develop a high-level summary of key findings from the interview data.

Results
There were mixed results about the attractiveness of GDCH and its suitability to the care home context. Participants felt that the images needed to be aligned much more closely with the meaning of adjacent text. Many participants felt that they would not have time to read a text-based website, and some suggested that more engaging content, including audio and video, may be preferable. Most participants felt that the overall concept of Germ Defence was clearly relevant to their context. Some felt that it might be a useful introduction for new staff members or a refresher for current staff, but others felt that it did not add anything to their existing IPC training. There were mixed opinions about the level of detail provided in the information offered by the site. While the goal-setting behavior change mechanism may have potential, the findings suggested that it may be unsuitable for care homes and more work is needed to refine it.

Conclusions
Much more work needs to be done to make Germ Defence more engaging, accessible, and relevant to the care home workforce. Our study highlights the challenges of rapidly adapting an existing intervention to a new context. Future research in this area will require a pragmatic methodological approach with a focus on implementation.
Implementasi Ansible pada Otomasi Honeypot Deployment Berbasis Web
Authors: Kurniawan Dharma , Saputra Yuris Mulya 
Published: November 2024

Dalam era digital yang semakin kompleks ini, keamanan sistem informasi menjadi masalah penting bagi organisasi di berbagai industri. Peningkatan serangan siber serta polanya yang semakin bervariatif bisa menimbulkan ancaman bagi kerahasiaan data atau integritas dari suatu organisasi. Di Indonesia, Badan Siber dan Sandi Negara (BSSN) mencatat bahwa hingga sepanjang bulan April 2022, serangan siber di Indonesia telah mencapai angka 100 juta kasus dengan jenis serangan yang didominasi oleh serangan ransomware dan malware. Salah satu solusi untuk mengatasi permasalahan ini adalah dengan mengimplementasikan sistem honeypot. Honeypot telah berkembang menjadi salah satu alat yang berguna untuk mengidentifikasi serangan dan mempelajari strategi penyerang, yang memungkinkan organisasi untuk memperkuat pertahanan mereka. Namun, penerapan dan pengelolaan honeypot secara manual dapat memakan banyak waktu dan sumber daya. Oleh karena itu, penelitian ini bertujuan untuk melakukan otomasi proses honeypot deployment dengan menggunakan alat manajemen konfigurasi yang populer yang dikenal sebagai Ansible. Selain itu, untuk mempermudah pengoperasian Ansible dalam melakukan honeypot deployment, maka dibuat sebuah aplikasi user friendly berbasis web. Aplikasi tidak hanya sekedar melakukan honeypot deployment, namun juga memantau prosesnya. Berdasarkan hasil pengujian, aplikasi berhasil melakukan honeypot deployment ke semua sensor yang berjalan di Google Cloud Platform dengan tiga region berbeda.
Cultura política no Brasil
Authors: Baquero Marcello 
Published: November 2024

Apesar do consenso no Brasil sobre a irreversibilidade da democracia representativo, surgiram questões sobre a sua qualidade. Um aspecto que atesta a fragilidade democrática é a forma como os partidos políticos funcionam e são vistos e avaliados por cidadãos brasileiros. As investigações confirmaram que essas instituições são avaliadas como menos confiáveis ​​e os mais corruptos. O objetivo deste trabalho é examinar como o conceito de capital social pode ser útil na possibilidade de gerar subsídios propositais para a constituição de uma base regulatória que apoie os partidos do país. Usando dados de pesquisas de opinião pública, examinamos como as pessoas decodificam a política e por que desconfiam dela. Os resultados que encontramos neste trabalho mostra que o capital social poderia ser uma das formas resgatar a imagem dos partidos.
Pedagogisk mappe – hva, hvorfor og hvordan?
Authors: Sandvoll Ragnhild , Borch Iris , Iversen Anita 
Published: November 2024

A teaching portfolio is a systematic and comprehensive documentation of a teacher’s pedagogical and didactic competence. In Norwegian higher education, teachers are required to document their teaching competence for assessment purposes. This chapter defines the teaching portfolio and addresses why it is suggested as an integral part of academic teachers’ professional lives. The portfolio serves not only as documentation of teachers’ abilities but also as a tool for academic teachers’ development in teaching. Moreover, creating a reflective teaching portfolio has the potential to contribute to the development of an academic community of practice distinguished by a scholarly approach to teaching and learning.
However, the authenticity of the portfolio is challenged by the expectations that it presents a selection of documents illustrating the best quality of work when being considered for employment or promotion. In other words – the “performative self” challenges the “authentic self”. But can these various intentions of the teaching portfolio be reconciled? In this chapter, we explore the potential and challenges, highlighting that teaching portfolios can be utilized for both the development of teaching and as a form of documentation. Our review of published papers on teaching portfolios indicates a substantial gap in research regarding their application. In concluding the chapter, we offer guidance on how to create a teaching portfolio that reflects a teacher’s educational philosophy, accomplishments, and ongoing professional development throughout their career.
Asymptomatic Hyperuricemia: A Nephro-Rheumatological Perspective
Authors: Moszczuk Barbara , Życińska Katarzyna , Mucha Krzysztof 
Published: November 2024

Abstract
Hyperuricemia (HU) is a common disorder associated with gout, kidney injury, and high cardiovascular risk. However, whether high serum uric acid (sUA) is a causative factor or just comorbidity remains unclear. When asked if asymptomatic hyperuricemic patients need treatment, even artificial intelligence in the form of the GPT chat provides an ambivalent answer and refers us to a healthcare provider. We believe that such discrepancies stem from an incomplete understanding of the role that uric acid (UA) plays inside and outside the cell. With the rapid development of genomics, proteomics, immunology, and novel biomarkers, we are armed with new data to help us better understand the weight of inborn and environmental factors on an individual’s UA concentrations. This review sums up the latest progress that has been made in the field of asymptomatic HU, compares the results presented by various research teams, and indicates new directions that emerge for future studies.
The Effects of Selective Serotonin Reuptake Inhibitors on Motility of Peripheral Smooth Muscles
Authors: Milosavljevic Jovana Z. , Folic Marko , Jankovic Slobodan , Milosavljevic Miloš N. , Milentijevic Milica , Stefanovic Srdjan M. 
Published: November 2024

Abstract
Selective serotonin reuptake inhibitors are chemically heterogeneous antidepressant drugs with small affinity for adrenergic, muscarinic and histaminergic receptors. This fact makes them one of the safest drugs among all antidepressants. However, the results of some experimental studies suggest that these antidepressants can modulate tone and spontaneous contractions of smooth muscle peripheral cells primarly by affecting the voltage-dependent ion channels. Fluoxetine causes relaxation of intestinal smooth muscle cells, contraction of gastric smooth muscle cells, and inhibition of muscular and neuronal nicotinic receptors, neuronal sodium channels, and voltage-dependent potassium channels on animal’s models. Paroxetine exhibits concentration-dependent stimulating effect on the spontaneous contractions of the isolated isthmus of human Fallopian tube. Citalopram induces contractions of the gastric fundus and the antrum, intestinal smooth muscle cell relaxation and has proarrhythmic effects due to blockage of Kv potassium channels. Escitalopram also blocks Kv channels of vascular smooth muscle cells of coronary arteries, as well as the hERG channels in the heart of rabbits, but it also shows concentration-dependent stimulating effect on the spontaneous contractions of the isolated ampulla of human Fallopian tube. Sertraline inhibits a wide range of heart ion channels including Kv channels on the vascular smooth muscles of rabbit coronary arteries. Fluvoxamine and dapoxetine also inhibit Kv channels of coronary arteries of rabbits, while at present there is no data on the effect of vilazodone and vortioxetine on peripheral smooth muscle cells. Knowledge of these peripheral effects of selective serotonin reuptake inhibitors could be of great importance in making treatment decisions for patients, such as in the case with paroxetine and escitalopram, which should be avoided in women of reproductive age due to the stimulating effect they have shown on spontaneous smooth muscle contractions of the human Fallopian tube.
Fiskalföderalismus in Deutschland – Was zu tun ist
Authors: Riedel Nadine , Simmler Martin 
Published: November 2024

Abstract
There is a need for some reform in the fiscal federal system in Germany. On the expenditure side, the relationship between administrative and legislative competences needs to be clarified. An orientation toward real values is recommended in the financial equalisation system (“Finanzausgleich”). In addition, the so-called population refinement (“Einwohnerveredelung”) should be reconsidered. We advocate greater tax autonomy for the federal states. A surcharge on income tax would be a good option here; the real estate transfer tax (“Grunderwerbsteuer”), on the other hand, is problematic as it is an autonomous tax instrument of the states. At the local level, we show that the trade tax (“Gewerbesteuer”) is accompanied by considerable economic distortions and we advocate for its abolition. The property tax (“Grundsteuer”), on the other hand, is well-suited as an autonomous local tax, and updating the outdated standard values offers an opportunity to enhance its effectiveness in local contexts.