bluuebunny/crossref_metadata_2025_split huggingface dataset:
MON-181 Evaluation of the GLUCOCARD Shine Connex Bluetooth Enabled Blood Glucose Monitoring System's Ease of Use
Authors: Walker Julie , Thompson Taylor , Gill Patricia , Shankar Raji 
Published: May 2019

Abstract
Background: It is important that a Blood Glucose Monitoring System (BGMS) is easy to use since it is a critical tool used in the self-management of diabetes, including the prevention of micro and macrovascular complications. The “Ease of Use” consumer study is typically evaluated as part of the FDA 510(k) approval process for BGMS. Purpose: The objective of this study was to further verify the Ease of Use of the GLUCOCARD Shine Connex Bluetooth Enabled BGMS. Methods: A total of 20 subjects with confirmed diabetes between the ages of 40 to 89 participated in the IRB-approved study at ARKRAY in Minneapolis, MN during October 2018. 80.0% of the subjects fell between the ages of 60 to 89 years of age. The subjects were asked to perform a fingerstick self-test and answer a questionnaire directed at the Ease of Use of the device and test strip. All the subjects responded to the topics in the questionnaire which included, “Removing a Test Strip from Bottle”, “Inserting a Test Strip into the Meter”, “Removing a Test Strip from the Meter”, “Performing a Blood Glucose Test from your Fingertip” and “Reading Meter Display”. The subjects were asked to rate the topics as Very Easy, Easy, OK, Difficult, or Very Difficult. For evaluation purposes, these topics were grouped as Positive [Very Easy/Easy/OK] and Negative [Difficult/Very Difficult]. Results: From the questionnaire, “Removing a Test Strip from Bottle” and “Inserting a Test Strip into the Meter” received a 95.0% positive rating while all the remaining topics received a 100.0% positive rating, including “Removing a Test Strip from the Meter”, “Performing a Blood Glucose Test from your Fingertip” and “Reading Meter Display”. Conclusion: The GLUCOCARD Shine Connex Bluetooth Enabled BGMS scored a 98.0% positive overall average Ease of Use rating by the subjects.
SUN-390 A Rare Case of Bilateral Macronodular Adrenal Hyperplasia Discovered Incidentally
Authors: Penaherrera Carlos , Mimms Remy , Pandit Amruta , Mohammed Ahmed , Raja Shashi , Patel Ronak , Melfi Robert 
Published: May 2019

Abstract
Introduction: Asymptomatic adrenal masses are often discovered incidentally while testing for unrelated conditions. A very uncommon finding is thickening and increased nodularity of both adrenal glands, which can lead to the patient being diagnosed with subclinical Cushing's syndrome, Conn's syndrome, or both. Case presentation: A 45-year-old African-American man presented to the hospital with a one-month history of increased abdominal girth, bilateral lower extremity edema and shortness of breath, with progressive epigastric abdominal pain which prompted admission. His medical history was relevant for obesity, coronary artery disease and heart failure with reduced ejection fraction. On examination he had a blood pressure of 152/99 mmHg, was diaphoretic, and complained of constant epigastric pain. Multiple purple and pale striae were visible along his abdomen, and he had pitting edema in both lower extremities. His initial laboratory studies showed a potassium of 2.6 mEq/L. A CT scan of the abdomen was relevant for bilaterally enlarged and tortuous adrenal glands, which the patient had no previous knowledge of. Diuresis greatly improved his edema and shortness of breath. Additional laboratory tests showed persistent hypokalemia, normal plasma renin activity and aldosterone, elevated fasting cortisol, normal metanephrines in 24-hour urine collection, and low ACTH level. A suppression test done by administering dexamethasone 0.5 mg every 6 hours for 2 days, was able to suppress the elevated cortisol levels. He was started on spironolactone, and underwent MRI of the abdomen, which confirmed bilateral multinodular adrenal hyperplasia with no imaging characteristics of pheochromocytoma. The patient was discharged home once his clinical status improved. Laboratory studies done at follow-up appointments showed persistently elevated cortisol, normal aldosterone to renin ratio, normal levels of plasma metanephrines and suppressed levels of ACTH. He was also referred to surgery for eventual bilateral adrenalectomy. Discussion: Primary bilateral macronodular adrenal hyperplasia (BMAH) is a very rare cause of endogenous Cushing's syndrome, representing less than 2% of cases. It is characterized by enlarged adrenal glands containing pigmented nodules that secrete excess cortisol and/or aldosterone (1). BMAH is often an incidental finding in patients with subclinical hyper-cortisolism. A low level of plasma ACTH along with bilaterally enlarged adrenal glands on imaging suggest the diagnosis, and this is confirmed with a dexamethasone suppression test. Accurate detection is important for guiding management, which includes pharmacological therapy and bilateral adrenalectomy. Reference: 1. De Venanzi A, Alencar GA, Bourdeau I, Fragoso MCBV, Lacroix A. Primary bilateral macronodular adrenal hyperplasia. Curr Opin Endocrinol Diabetes Obes. 2014 Jun;21(3):177-84.
SUN-563 TSH Elevation after Seizure: An Underappreciated Cause of Nonthyroidal Illness Syndrome
Authors: Patel Ronak , Laufgraben Marc 
Published: May 2019

Abstract
Introduction: TSH is commonly assessed at hospital admission to exclude thyroid dysfunction as the cause of a patient’s presentation. However, thyroid function tests (TFTs) are commonly altered as a result of the condition leading to the presentation, referred to as nonthyroidal illness syndrome (NTIS). Thus, it is often difficult to interpret the true meaning of abnormal TFTs in hospitalized patient. In fact, hypothalamic-pituitary-thyroid axis can be altered in up to 75% of hospitalized patient (1). Typically, the TSH in NTIS is normal or low, but can temporarily rise above normal as the patient recovers from NTIS (2). We present the case of a patient who had significant TSH elevation immediately after a prolonged seizure. Clinical Case: A 93-year-old female with past medical history of seizure disorder on Levetiracetam, presented with a prolonged seizure. Her blood count, metabolic profile, and Levetiracetam level were all unremarkable. There were no acute changes on a noncontrast head CT. Her only notable test result was TSH 26.30 MIU/L (normal range 0.27-4.20 MIU/L) with a Free T4 1.2 ng/dL (normal range 0.9-1.7 ng/dL). She had no prior history of thyroid disease or family history of thyroid conditions. Endocrinology was consulted for the interpretation of her TFTs. The differential diagnosis included subclinical hypothyroidism and NTIS. TSH and Free T4 were rechecked two days later and were then both within normal range. The patient was diagnosed as euthyroid with transient TSH elevation due to seizure. Conclusions: The case highlights, generally, that TFTs can be unreliable in an acute illness, and that seizures may cause an acute, transient rise in TSH. In our case, the patient’s TSH elevation, occurring after a seizure, normalized on repeat testing two days later. In studies on TSH levels following ECT-induced seizures in depressed patients, researchers demonstrated transient TSH elevations (3). Wada et al. reported a similar case of a patient with non-convulsive status epilepticus with TSH elevation that normalized spontaneously (4). We advise that the diagnosis of subclinical hypothyroidism not be made in a patient presenting with a recent seizure, as the seizure itself may be the cause of elevated TSH. As with most cases of NTIS, follow up over time may reveal that the patient is, in fact, euthyroid. References: (1) Ganesan K, Wadud K. (2018). Euthyroid Sick Syndrome. In: StatPearls. Treasure Island (FL) (2) DeGroot LJ. (2001). The Non-Thyroidal Illness Syndrome. In: Endotext. South Dartmouth (MA) (3) Dykes, S., Scott, A., Gow, S., & Whalley, L. (1987). Effects of seizure duration on serum TSH concentration after ECT. Psychoneuroendocrinology, 12(6), 477-482. (4) Wada A, Suzuki Y, Midorikawa S, et al. (2011). Thyroid-stimulating hormone elevation misdiagnosed as subclinical hypothyroidism following non-convulsive status epilepticus: a case report. J Med Case Rep., 5:432.
Queering the Chicana/o Archive in Felicia Luna Lemus’s Like Son
Authors: Lederman Emily 
Published: May 2019

Abstract
This essay argues that a queer archive in Felicia Luna Lemus’s Like Son (2007) recovers the historical Mexican figure Nahui Olin and allows the trans protagonist to navigate less tangible inheritances, including a destructive romantic legacy and a complex Mexican American identity. This essay asks whether, and how, inheritances can be curated and posits that queer archival practices are useful for simultaneously drawing from and rejecting powerful familial and cultural legacies. At the end the essay situates Like Son as part of a group of contemporary Chicana/o texts that claim control over the access and representation of Chicana/o histories and imagine queer futures through queer archives and archival practices. The affective and political possibilities of these queer archives further discourse of the interdisciplinary archival turn. U.S. multiethnic literature is often lauded for helping to fill in the gaps of the dominant historical archive by providing access to silenced histories of the Americas, yet contemporary Chicana/o texts such as Like Son also challenge the epistemologies and power structures that undergird institutional archives.
Polemics of Love and the Family in A New Day in Old Sana’a
Authors: Mabura Lily , Husni Ronak 
Published: May 2019

Abstract
Bader Hirsi (1968–) is a renowned Yemeni British filmmaker whose works include the documentary The English Sheikh and the Yemeni Gentleman (2000) and the feature film A New Day in Old Sana’a (2005). This essay explores how photography and film creatively interact in A New Day in Old Sana’a to tease out the peculiarities of love and marriage against a backdrop of intersecting socioeconomic factors such as tradition, gender, race, and national class. The essay, affirmed by Hirsi himself, also makes use of interdisciplinarity to evaluate how Hirsi’s film embodies Yemen’s heritage, which includes the historical influence of the Horn of Africa and its relationship with the West.
Breaking Silences
Authors: Hopson Cheryl R. 
Published: May 2019

Abstract:
The focus of this essay is a memoir of first-time biological motherhood, Baby Love, by Third Wave feminist writer and cultural critic Rebecca Walker (2007). This essay enlists a black and Third Wave feminist intersectional theoretic to argue that Walker, a famous second-generation black and Third Wave feminist daughter and mother, forwards a child-and-parent-centric model of motherhood that privileges biological bonds over chosen bonds (e.g., step, adoptive, othermothers) with one’s children. A self-identified bisexual woman, Walker centralizes in Baby Love a heterosexual nuclear family model that is informed by feminist ideology and takes shape in a twenty-first-century material reality transformed by feminism. Second to this, and in the context of her relationship with her famous African American mother, Walker characterizes the biological (black feminist) mother-daughter relationship as controlled by the mother and infantilizing most especially for childless daughters who therefore function as muted and acted-upon subjects in the (black feminist) mother-daughter dyad.
The Rise of theMadre Abnegada(Selfless Mother)
Authors: Gaytán Marie Sarita 
Published: May 2019

AbstractHailed by fans and critics as “Mexico’s Mother,” and later “Mexico’s Grandmother,” the actor Sara García exemplified the sentimental attributes associated with notions of womanhood. As Mexico’s mother par excellence, García created multigenerational portrayals that introduced audiences to a martyr-like maternal figure: the madre abnegada (selfless mother). This essay examines the origin, diffusion, and popularity of this uniquely Mexican subjectivity. Drawing on poetry, song lyrics, movie reviews, and an analysis of the film Mi madrecita (1940), the essay argues that, in combination with emerging priorities of writers and directors, García’s fashioning of the madre abnegada tapped into and vitalized the sentimental relationship between mother and child and between nation and citizen. In theorizing these relations, the essay introduces the term national maternal as a means of capturing the gendered, raced, classed, spiritual, and patriotic dynamics through which notions of motherhood in Mexico were structured. The national maternal rose to prominence as women and progressive leaders challenged exacting patriarchal family arrangements.
Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells
Authors: Jetta Deekshitha , Gottlieb Philip A. , Verma Deepika , Sachs Frederick , Hua Susan Z. 
Published: May 2019

ABSTRACT
The cell nucleus responds to mechanical cues with changes in size, morphology and motility. Previous work has shown that external forces couple to nuclei through the cytoskeleton network, but we show here that changes in nuclear shape can be driven solely by calcium levels. Fluid shear stress applied to MDCK cells caused the nuclei to shrink through a Ca2+-dependent signaling pathway. Inhibiting mechanosensitive Piezo1 channels through treatment with GsMTx4 prevented nuclear shrinkage. Piezo1 knockdown also significantly reduced the nuclear shrinkage. Activation of Piezo1 with the agonist Yoda1 caused similar nucleus shrinkage in cells not exposed to shear stress. These results demonstrate that the Piezo1 channel is a key element for transmitting shear force input to nuclei. To ascertain the relative contribution of Ca2+ to cytoskeleton perturbation, we examined F-actin reorganization under shear stress and static conditions, and showed that reorganization of the cytoskeleton is not necessary for nuclear shrinkage. These results emphasize the role of the mechanosensitive channels as primary transducers in force transmission to the nucleus.
Identification and characterization of the land-plant-specific microtubule nucleation factor MACET4
Authors: Schmidt Sharol , Smertenko Andrei 
Published: May 2019

ABSTRACT
Here, we show that the embryophyte (land-plant)-specific protein MACERATOR4 (MACET4) binds microtubules in vitro and in vivo, promotes microtubule polymerization at sub-critical tubulin concentrations, decreases the lag phase in microtubule bulk polymerization assays, and colocalizes with microtubule nucleation sites. Furthermore, we find that MACET4 forms oligomers that induce aster formation in vitro in a manner that is similar to aster formation mediated by centrosomes and TPX2. MACET4 is expressed during cell division and accumulates at the microtubule nucleation regions of the plant-specific cytokinetic microtubule array, the phragmoplast. We found that MACET4 localizes to the preprophase band and the cortical division zone, but not the spindle. MACET4 appears as cytoplasmic foci in vivo and forms octamers in vitro. Transient expression in tobacco leaf pavement cells results in labeling of shrinking plus- and minus-ends. MACET4 facilitates microtubule depolymerization by increasing the frequency of catastrophes in vivo and by suppressing rescues in vitro. Microtubules formed in the presence of MACET4 in vitro are shorter, most likely due to the depletion of the free tubulin pool. Accordingly, MACET4 knockdown results in longer phragmoplasts. We conclude that the direct activity of MACET4 is in promoting microtubule nucleation.
This article has an associated First Person interview with the first author of the paper.
Software comparison to analyze bone radiomics from high resolution CBCT scans of mandibular condyles
Authors: Bianchi Jonas , Gonçalves João Roberto , Ruellas Antonio Carlos de Oliveira , Vimort Jean-Baptiste , Yatabe Marília , Paniagua Beatriz , Hernandez Pablo , Benavides Erika , Soki Fabiana Naomi , Cevidanes Lucia Helena Soares 
Published: May 2019

Objectives: Radiomics refers to the extraction and analysis of advanced quantitative imaging from medical images to diagnose and/or predict diseases. In the dentistry field, the bone data from mandibular condyles could be computationally analyzed using the voxel information provided by high-resolution CBCT scans to increase the diagnostic power of temporomandibular joint (TMJ) conditions. However, such quantitative information demands innovative computational software, algorithm implementation, and validation. Our study's aim was to compare a newly developed BoneTexture application to two-consolidated software with previous applications in the medical field, Ibex and BoneJ, to extract bone morphometric and textural features from mandibular condyles. Methods: We used an imaging database of HR-CBCT TMJs scans with an isotropic voxel size of 0.08 mm3 . A single group with 66 distinct mandibular condyles composed the final sample. We calculated 18 variables for bone textural features and 5 for bone morphometric measurements using the Ibex, BoneJ and BoneTexture applications. Spearman correlation and Bland–Altman plot analyses were done to compare the agreement among software. Results: The results showed a high Spearman correlation among the software applications ( r = 0.7–1), with statistical significance for all variables, except Grey Level Non-Uniformity and Short Run Emphasis. The Bland–Altman vertical axis showed, in general, good agreement between the software applications and the horizontal axis showed a narrow average distribution for Correlation, Long Run Emphasis and Long Run High Grey Level Emphasis. Conclusions: Our data showed consistency among the three applications to analyze bone radiomics in high-resolution CBCT. Further studies are necessary to evaluate the applicability of those variables as new bone imaging biomarkers to diagnose bone diseases affecting TMJs.
Timing between age at first sexual intercourse and age at first use of contraception among adolescents and young adults in Niger: What role do education and place of residence play?
Authors: Olakunle Abibatou Agbéké , Banougnin Boladé Hamed 
Published: May 2019

Background: Low contraceptive use among women in Niger is one of main causes of early childbearing and unwanted pregnancies, which affect maternal and child health. Education and place of residence have been cited as factors affecting modern contraceptive use. Methods: We investigated the separate and joint effects of the place of residence and education on the time to modern contraceptive uptake among women aged 15-24 in Niger. The study used data from the second round of the 2016 Niger Performance Monitoring and Accountability 2020 (PMA2020) project. Survival analysis was applied for 830 women. Results: Nelson-Aalen curves show that urban women had higher hazards of (and shorter delays in) modern contraceptive uptake as compared to their rural counterparts. Also, the higher the level of education, the higher the hazards of (and the shorter the delays in) modern contraceptive uptake. Findings from the multivariate (survival) analysis confirms these figures and provides the net effect of the place of residence on modern contraceptive uptake. Whether living in urban or rural areas of Niger, what matters more is the level of education. Conclusions: Family planning programmes concerning adolescent and young women should focus more on women with no education and those that are illiterate.
Revisiting cognitive tools from a social and motivational perspective
Authors: Ge Xun , Turk Murat , Hung Woei 
Published: May 2019

The concept of computers as cognitive tools has been revisited to provide insight into the motivational and social dimension in light of the emerging technologies. Central to this concept are the two opposing philosophical views: learning from technology (amplification view of technology) versus learning with technology (constructivist view of technology). A literature review is provided on the paradigm shift in educational technologies from the “learning from paradigm” to the “learning with” paradigm. While the literature review shows powerful affordances of emerging technologies in engaging community of learners in knowledge construction and building, a critical analysis also indicates a significant gap in the traditional conception of cognitive tools, that is, a lack of research in the motivational and social dimension. Therefore, the purpose of this study was to investigate the motivational and social dimensions of cognitive tools in the context of emerging technologies, with the substantiation of empirical evidence from the literature.
Využití paralelního korpusu v translatologii (na základě česko-polského InterCorpu)
Authors: Charciarek Andrzej 
Published: May 2019

Tento článek je věnován využití paralelního korpusu InterCorp v teorii překladu. Ve výzkumu byly použity vybrané fráze, které ukazují možnosti využití paralel- ního korpusu InterCorp. Zvláštní pozornost byla věnována rovnocennosti překladů a jeho kritériem s ohledem na materiál z paralelního korpusu. Také byla popsána specificita česko-polského a polsko-českého překladu, který poskytoval kontext pro konkrétní zdroje InterCorp. Analýza ukázala užitečnost materiálu korpusu při hledání vhodných překladatelských řešení. Článek přispívá k teoretickému badání, které ukazuje úlohu paralelních korpusů v práci překladatele.
Applying the theory of planned behavior to determine factors associated with physical activity by women with hypertension in rural areas of Iran
Authors: Hatefnia Effat , Alizadeh Kobra , Ghorbani Mostafa 
Published: May 2019

Abstract

Background
Hypertension is the leading preventable cause of premature deaths worldwide. Physical activity reduces the levels of blood lipids and blood pressure in people suffering from hypertension.

Objectives
To apply the theory of planned behavior (TPB) to determine factors associated with physical activity by women with hypertension who were referred to health care centers in Kiashahr in 2016.

Methods
The present observational study was conducted in a cross-section of 215 women diagnosed with hypertension who had records in health care centers in Kiashahr and who were recruited through census from August to September 2016. The data collection tool was a custom-designed questionnaire based on the TPB, and the collected data were analyzed using descriptive and analytical statistical methods.

Results
The mean scores of knowledge, attitudes, subjective norms, perceived behavioral control, and intention to undertake physical activity were significantly (P < 0.01) higher among women who performed regular physical activity than in those without regular physical activity. Constructs including behavioral intention (P < 0.001, odds ratio (OR) 1.36, 95% confidence interval (CI) 1.15, 1.61) and attitude (P = 0.004, OR 1.27, 95% CI 1.08, 1.50) were significant predictors for undertaking physical activities.

Conclusions
Attitude and behavioral intention were predictors for undertaking physical activities. We recommended the design of interventional programs based on these 2 factors for women with hypertension living in rural areas of Iran.