bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desilusão: Impasses Clínicos e Políticos diante dos Dilemas de nosso Tempo
Authors: Rosa Miriam Debieux , Ferreira Patrícia Do Prado , Alencar Rodrigo 
Published: January 2019

Acontecimentos sociais e políticos, nacionais e internacionais, têm abalado nosso cotidiano. Conquistas que pareciam sedimentadas na direção da democracia e nos temas relativos aos direitos humanos, conquistas sociais e considerações éticas na vida política, têm sido substituídas por chavões e discursos de ódio, racismo e xenofobia sob a lógica da guerra. Desse modo, têm sido enfrentados fluxos massivos de imigrantes, frutos de guerras e violências, atentados terroristas e uma tensão cotidiana em que o debate localiza no outro o perigo: generaliza-se a figura do terrorista. Vamos propor um deslocamento da lógica da guerra a fim de dialogar sobre a queda dos ideais e das ilusões e as dificuldades de traçar direções para o futuro. Vamos apontar o imbricado enlace entre ética do desejo, política e resistência à instrumentação social do gozo. Entendemos que perder um ideal é diferente de perder uma ilusão, crença ou delírio. A descrença, a desilusão, tem seus efeitos – um deles é agarrar-se à fantasia delirante. A idealização é um processo que envolve o engrandecimento e superestimação do objeto, não dizendo respeito ao ideal. A aflição psíquica nomeada “desilusão” estende-se dos ideais culturais (no plano do ideal-do-Eu) às expectativas do Eu (plano do Eu-ideal). Essa questão nos alerta para o encobrimento de outra ilusão, de autoengendramento, de poder superar a dependência simbólica ao Outro. Diferenciar esses termos nos permite apontar o imbricado enlace entre ética do desejo, política e a resistência à instrumentação social do gozo. Quanto à posição da psicanálise, retomaremos a frase de Lacan em Ciência e verdade (1966/1998): “Por nossa posição de sujeito somos sempre responsáveis. Que chamem a isto como quiserem, terrorismo”.
Burgerparticipatie in het omgevingsrecht
Authors: de Brauw C. , van Amstel-van Saane M. , de Cock Buning Tj. 
Published: January 2019

Burgerparticipatie in het omgevingsrecht. Zet de regulering – nu en in de Omgevingswet – aan tot het instellen van bezwaar en beroep?
De auteurs bespreken burgerparticipatie bij ruimtelijke besluitvorming. Daarbij wordt aandacht besteed aan de achtergrond van burgerparticipatie, de vorderingen die in recente wetgeving zijn gemaakt en de toekomst van burgerparticipatie in de Omgevingswet. Vanuit sociaalwetenschappelijk oogpunt wordt betoogd dat de wettelijke verankering in afdeling 3.4 Awb onvoldoende is. Burgerparticipatie is pas effectief als daadwerkelijk invloed ontstaat bij de participanten worden geactiveerd om deel te nemen en de mogelijkheid krijgen om het beslissingsproces te beïnvloeden.
Diplomacia Corporativa. El caso de la cadena de hoteles Meliá
Authors: Arce Izquierdo Amanda , Jiménez Palma Peña 
Published: January 2019

Comunicar es imprescindible hoy para las instituciones, organizaciones o empresas. Lo importante es saber hacerlo y tener presentes los principales grupos de interés. Sobre este pilar se asienta la Diplomacia Corporativa, como herramienta que contribuye a gestionar las relaciones así como la comunicación, la imagen y la reputación de una compañía, institución u organización. La internacionalización y la globalización aconsejan que la comunicación corporativa deba añadir en sus relaciones institucionales todo lo que la diplomacia puede aportarle.El presente artículo se centra en el concepto y aplicación de la «diplomacia corporativa» a las empresas e instituciones, así como en la figura del diplomático corporativo en las organizaciones y sus competencias. Además, planteamos un estudio de caso sobre la cadena Meliá Hotels International, pionera en crear un Gabinete Institucional y de Diplomacia Corporativa (DC). Diplomacy is based on this concept, as a tool that contributes to managing relationships as well as communication, corporate image and the reputation of a company, institution or organization. Internationalization and globalization advises that corporate communication should add, in its institutional relations, everything that diplomacy can provide.This article focuses on the concept and application of "corporate diplomacy" to companies and institutions, and on the corporate diplomats and their competencies. We also propose a case study on the Meliá Hotels International chain, a pioneer in creating an Institutional and Corporate Diplomacy (CD) Cabinet.
What is the place of religious schools in pluralistic democratic societies? A liberal approach to the problematic of religious schools and democratic citizenship in Western societies. The Spanish case
Authors: Grau Callizo Ignasi 
Published: January 2019

The following article aims to determine under which circumstances the establishment of denominational schools must be allowed in democratic societies. The possible opening of a Muslim Brotherhood School in Spain requires a new approach on the presence of religious schools through the study of the collision between two protected goods raise: freedom of religion and democratic citizenship. Thus, it is first considered which space democratic States must grant to religious institu-tions, turning to Cécile Laborde’s considerations on French laicism from a liberal Span-ish perspective. Subsequently, the article proceeds to reconcile freedom of religion and democratic citizenship education, choosing the political liberal approach over the com-prehensive liberal approach, since it provides solutions that are easier to assume by the standard reasonable citizen. Once the theoretical framework has been established, the tension between these two goods is analyzed through the triangle of actors of Arneson and Saphiro, in order to determine under what circumstances the existence of denomina-tional schools must be tolerated. Said triangle shows the tension between the State, who seeks to educate good citizens (democratic citizenship education), the parents, who seek that their children share their same conception of the good life (freedom of religion) and, in between, the children, whose best interest must come first. On the one hand, the results do not only show that religious institutions are compatible with democratic States, but also that said States must guarantee, in pluralistic societies, the different conceptions of the good life. On the other hand, regarding the conciliation between freedom of religion and democratic citizenship, the article showcases that, in order for the best interest of the child to be guaranteed, neither the State nor the parents can prevail, rather both interests must balance in the following way: the State must allow the existence of confessional schools as long as they teach the core contents of demo-cratic citizenship education. Finally, the article argues that democratic citizenship education in confessional schools is not inferior to that of public schools, and criticizes the positions according to which citi-zens must put aside the religious aspect in democratic societies. The article pretends to discuss the traditional liberal theoretical framework, from which it has reflected the reli-gious education, compelling a re-reading of the triangle of actors.
Les Livres dans la rue
Authors: Charette Christiane 
Published: January 2019

Le nombre croissant d’analphabètes et, dans les quartiers où l’on retrouve les plus démunis, l’indifférence des enfants face à leur bibliothèque sont à l’origine du projet les Livres dans la rue. Pensée et réalisée par la Division des bibliothèques de la Ville de Montréal en collaboration avec l’Opération renouveau de la Commission des écoles catholiques de Montréal, l’expérience vise à rapprocher les livres du vécu des jeunes.
Après avoir rappelé les débuts du projet, l’auteure en décrit les différentes activités d’animation et analyse l’influence des Livres dans la rue auprès des jeunes lecteurs.
Espacios y prácticas de participación ciudadana. Propuestas educativas desde una mirada intercultural
Authors: Aguado Teresa , Melero Héctor S. , Gil-Jaurena Inés 
Published: January 2019

El artículo presenta la investigación de tesis doctoral que se ha desarrollado en cuatro espacios de participación ciudadana de la ciudad de Madrid durante tres años (2015/2017). Consideramos que la ciudadanía se aprende ejerciéndola y que los espacios de participación son escuelas de ciudadanía. La finalidad del estudio es formular propuestas educativas para el aprendizaje de la ciudadanía activa a partir del análisis de lo que sucede en dichos espacios. El texto se estructura en torno a estos apartados: 1) reflexiones y premisas en relación a la participación y la educación para la ciudadanía; 2) antecedentes directos de la investigación y las continuidades que se dan en este trabajo; 3) enfoque intercultural desde el que comprendemos la participación ciudadana; 4) estudio etnográfico realizado mediante observación participante y entrevistas dirigidas a 30 informantes clave. Se describen los cuatro casos de estudio y el proceso de análisis a través de la definición categorial; 5) resultados organizados en tres grandes bloques temáticos: diversidad y complejidad, visión relacional y prácticas educativas; 6) propuestas educativas derivadas de los resultados y dirigidas tanto a profesionales de la educación como a personas implicadas en los espacios de participación ciudadana
Bulk Photodriven CO2 Conversion through TiO2@Si(HIPE) Monolithic Macrocellular Foams
Authors: Bernadet Sophie , Tavernier Eugénie , Ta Duc‐Minh , Vallée Renaud A. L. , Ravaine Serge , Fécant Antoine , Backov Rénal 
Published: January 2019

AbstractOperating photo‐induced reactions exclusively on catalyst surfaces while not exploiting the full catalyst volume generates a major footprint penalty for the photocatalytic reactor and leads to an inefficient use of the catalytic material. Photonic investigations clearly show that the solid foams have a strongly multidiffusive character, with photons being significantly trapped within the sample cores while addressing a photon mean free path lt = 20.1 ± 1.3 µm. This 3D process both greatly limits back‐reactions and promotes outstanding selectivity toward methane (around 80%) generation, and even ethane (around 18%) through C‐C coupling reaction, with residual carbon monoxide and dihydrogen contents (around 2%). Silica–titania TiO2@Si(HIPE) self‐standing macrocellular catalysts lead to optimal efficient thicknesses up to 20 times those of powders, thereby enhancing the way for real 3D‐photodriven catalytic processes above the millimeter scale and up to a 6 mm thickness. A rather simple Langmuir–Hinshelwood based kinetic model is proposed which highlights the strong dependence of photocatalytic reaction rates on light scattering and the crucial role on oxidation back‐reactions. In addition, a strong correlation between light attenuation coefficient and photon mean free path and median pore aperture diameter is demonstrated, offering thus a tool for photocatalytic behavior prediction.
Nanoconfinement‐Induced Giant Electrocaloric Effect in Ferroelectric Polymer Nanowire Array Integrated with Aluminum Oxide Membrane to Exhibit Record Cooling Power Density
Authors: Zhang Guangzu , Weng Lingxi , Hu Zhaoyao , Liu Yang , Bao Runxi , Zhao Peng , Feng Hao , Yang Nuo , Li Ming‐Yu , Zhang Sulin , Jiang Shenglin , Wang Qing 
Published: January 2019

AbstractThe electrocaloric effect (ECE) offers a unique mechanism to realize environmentally friendly and highly efficient solid‐state cooling that completely differs from the conventional vapor‐compression refrigeration. Here a new class of hybrid films composed of ferroelectric polymer nanowire array and anodic aluminum oxide (AAO) membrane is reported, which displays pronounced ECE driven by relatively low electric fields. Under confinement and orientation of AAO channels on the crystallization of the polymer, the polymer nanowire array shows substantially enhanced ECE that is about three times that of the corresponding thin films. Simultaneously, the integrated AAO membrane forms thermally conducting channels for the polymer nanowires, enabling the efficient transfer of cooling energy and operation of the EC materials under high frequencies, which are unattainable based on the currently available EC structures. Consequently, the integrated polymer nanowire–AAO hybrid film exhibits the state‐of‐the‐art cooling power density, outperforming the current ferroelectric polymers, ceramics, and composites. This work opens a new route for the development of scalable, high‐performance EC materials for next‐generation refrigeration.
Highly Dynamic Shape Memory Alloy Actuator for Fast Moving Soft Robots
Authors: Huang Xiaonan , Kumar Kitty , Jawed Mohammad K. , Mohammadi Nasab Amir , Ye Zisheng , Shan Wanliang , Majidi Carmel 
Published: January 2019

AbstractShape memory alloys (SMAs) are popular as actuators for soft bioinspired robots because they are naturally compliant, have high work density, and can be operated using miniaturized on‐board electronics for power and control. However, SMA actuators typically exhibit limited bandwidth due to the long duration of time required for the alloy to cool down and return to its natural shape and compliance following electrical actuation. This challenge is addressed by constructing SMA‐based actuators out of thermally conductive elastomers and examining the influence of electrical current and actuation frequency on blocking force, bending amplitude, and operating temperature. The actuator is composed of a U‐shape SMA wire that is sandwiched between layers of stretched and unstretched thermal elastomer. Based on the studies, the ability is demonstrated to create a highly dynamic soft actuator that weighs 3.7 g, generates a force of ≈0.2 N, bends with curvature change of ≈60 m−1 in 0.15 s, and can be activated with a frequency above 0.3 Hz with a pair of miniature 3.7 V lithium–polymer batteries. Together, these properties allow the actuator to be used as an “artificial muscle” for a variety of tethered and untethered soft robotic systems capable of fast dynamic locomotion.
All in the Family – Touch Versus Olfaction in Moles
Authors: Catania Kenneth C. 
Published: January 2019

ABSTRACTHere I review, compare, and contrast the neurobiology and behavior of the common, eastern mole (Scalopus aquaticus) and the star‐nosed mole (Condylura cristata). These two species are part of the same family (Talpidae) and have similar body size and general morphology. But they differ in sensory specializations, complexity of neocortical organization, and behavior. The star‐nosed mole has an elaborate mechanosensory organ—the star—consisting of 22 epidermal appendages (rays) covered with 25,000 touch domes called Eimer's organs. This densely innervated structure is represented in the neocortex in three different somatosensory maps, each visible in flattened neocortical sections as a series of 11 modules representing the 11 rays from the contralateral body. The 11th ray is greatly magnified in primary somatosensory cortex (S1). Behavioral studies show the star is moved in a saccadic manner and the 11th ray is a high‐resolution tactile fovea, allowing star‐nosed moles to forage on small prey with unprecedented speed and efficiency. In contrast, common mole noses lack Eimer's organs, their neocortex contains only two cortical maps of the nose, and they cannot localize small prey. Yet common moles have exceptional olfactory abilities, sniffing in stereo to rapidly localize discrete odor sources originating from larger prey. In addition, common moles are shown to track odorant trails laid down by moving prey. These results highlight the surprising abilities of species once thought to be simple, and the usefulness of diverse species in revealing general principles of brain organization and behavior. Anat Rec, 2019. © 2019 American Association for Anatomy.
Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes: A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank
Authors: Hindy George , Åkesson Kristina E. , Melander Olle , Aragam Krishna G. , Haas Mary E. , Nilsson Peter M. , Kadam Umesh T. , Orho‐Melander Marju 
Published: January 2019

ObjectiveTo investigate the causal role of cardiometabolic risk factors in osteoarthritis (OA) using associated genetic variants.MethodsWe studied 27,691 adults from the Malmö Diet and Cancer Study (MDCS) and replicated novel findings among 376,435 adults from the UK Biobank. Trait‐specific polygenic risk scores for low‐density lipoprotein (LDL) and high‐density lipoprotein (HDL) cholesterol levels, triglyceride levels, body mass index (BMI), fasting plasma glucose (FPG) levels, and systolic blood pressure (BP) were used to test the associations of genetically predicted elevations in each trait with incident OA diagnosis (n = 3,559), OA joint replacement (n = 2,780), or both (total OA; n = 4,226) in Mendelian randomization (MR) analyses in the MDCS, and with self‐reported and/or hospital‐diagnosed OA (n = 65,213) in the UK Biobank. Multivariable MR, MR‐Egger, and weighted median MR were used to adjust for potential pleiotropic biases.ResultsIn the MDCS, genetically predicted elevation in LDL cholesterol level was associated with a lower risk of OA diagnosis (odds ratio [OR] 0.83 [95% confidence interval (95% CI) 0.73–0.95] per 1SD increase) and total OA (OR 0.87 [95% CI 0.78–0.98]), which was supported by multivariable MR for OA diagnosis (OR 0.84 [95% CI 0.75–0.95]) and total OA (0.87 [95% CI 0.78–0.97]), and by conventional 2‐sample MR for OA diagnosis (OR 0.86 [95% CI 0.75–0.98]). MR‐Egger indicated no pleiotropic bias. Genetically predicted elevation in BMI was associated with an increased risk of OA diagnosis (OR 1.65 [95% CI 1.14–2.41]), while MR‐Egger indicated pleiotropic bias and a larger association with OA diagnosis (OR 3.25 [1.26–8.39]), OA joint replacement (OR 3.81 [95% CI 1.39–10.4]), and total OA (OR 3.41 [95% CI 1.43–8.15]). No associations were observed between genetically predicted HDL cholesterol level, triglyceride level, FPG level, or systolic BP and OA outcomes. The associations with LDL cholesterol levels were replicated in the UK Biobank (OR 0.95 [95% CI 0.93–0.98]).ConclusionOur MR study provides evidence of a causal role of lower LDL cholesterol level and higher BMI in OA.
Does designing environmental sustainability disclosure quality measures make a difference?
Authors: Helfaya Akrum , Whittington Mark 
Published: January 2019

AbstractAssessing the quality of information disclosed by companies is a complex task. Accounting studies usually rely on analysing the content of corporate reports using measures to obtain a proxy for the information reported by companies. However, there is no consensus about the best design for these measures. The objective of the current paper is to investigate if there are significant differences in the results generated from seven alternative measures for assessing the quality of FTSE100 environmental sustainability reporting. Seven measures/indices have been used to assess disclosure quality. The three unidimensional measures include two “quantity measures” and one “scope measure” that measure the volume and width/coverage of information, respectively. Three compound measures are adopted from the literature, and the final measure is a multidimensional quality model, based on the results of a questionnaire ascertaining the perceptions of 86 preparers and 177 users of annual report (AR) and/stand‐alone corporate responsibility report (CRR). Although the results of the empirical analysis indicate that the measures are significantly correlated, the choice of a specific method can result in the very different ranking of companies. The evidence presented indicates that the choice of measure is of key importance.
A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg
Authors: Frederick Rachel , Vuillermin Peter , Tang Mimi L. K. , Ponsonby Anne‐Louise , Webster Elise , Saffery Richard , Collier Fiona ,   the Barwon Infant Study Investigator Group
Published: January 2019

Key Clinical MessageThis case suggests a possible association between Klinefelter Syndrome and decreased regulatory T cells (Treg) cells, relating to an increased risk of allergic and autoimmune disorders in these patients. The immune phenotyping of the circulating FOXP3+ naive Treg populations in KS patients may help to indicate this predisposition.
Interindividual variation in the cytochrome P4501A response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in herring gull embryo hepatocytes
Authors: Head Jessica A. , Kennedy Sean W. 
Published: January 2019

Abstract

Exposure to dioxin-like compounds is consistently associated with concentration-dependent induction of cytochrome P4501A (CYP1A) enzymes in primary cultures of avian hepatocytes. We have previously demonstrated that the median effective concentration (EC50) for induction of this response is predictive of in vivo sensitivity to dioxin-like compounds in birds. We investigated sources of interindividual variation in the CYP1A response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in wild herring gulls and considered how this variation may complicate dioxin sensitivity estimates based on the CYP1A bioassay. Concentration-dependent effects of TCDD on CYP1A mRNA expression were characterized in 55 hepatocyte cultures prepared from individual herring gull embryos. A large degree of variability was observed among the hepatocyte culture preparations. For example, 1) basal CYP1A4 and CYP1A5 mRNA expression varied by 20- and 126-fold, respectively, among individuals, and 2) exposure to TCDD induced CYP1A4 mRNA expression by 57-fold in the most responsive sample but did not significantly induce CYP1A4 mRNA expression above baseline values in 42% of hepatocyte culture preparations. Environmental and genetic factors contributing to the observed variability are discussed. Despite the large amount of interindividual variation, we conclude that reproducible EC50-based estimates of species sensitivity can be obtained from the CYP1A cell culture bioassay when samples are collected from relatively uncontaminated colonies. Environ Toxicol Chem 2019;38:660–670. © 2019 SETAC
Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism
Authors: Paul Anju , Mishra Archita , Surolia Avadhesha , Vijayan Mamannamana 
Published: January 2019

AbstractArgininosuccinate lyase catalyses the reversible breakdown of argininosuccinate into arginine and fumarate and is known to form tetramers in its quaternary association. The absence of structures involving competent enzymes bound to substrate/products came in the way of the precise elucidation of the catalytic mechanism of this family of proteins. Crystal structures of the enzyme from Mycobacterium tuberculosis in an unliganded form and its complex with the substrate/products have now been determined at 2.2 and 2.7 Å, respectively. The refinement of the structure of the complex was bedevilled by the presence of a lattice translocation defect. The two tetramers in the apo‐crystals and the one in the crystals of the liganded protein, have the same structure except for the movements associated with enzyme action. Each molecule consists of an N‐domain, an M‐domain, and a C‐domain. The molecule consists of four binding sites, each made up of peptide stretches from three subunits. Three binding sites appear to be occupied by the ligand in the transition state, while the products occupy the fourth site. The structure exhibits the movement of a loop in the M‐domain and parts of the C‐domain. This is the first instance when the appropriate movements are observed in a complex with bound substrate/product. The detailed picture of the binding site, active site residues and the movements associated with catalysis thus obtained, enabled a revisit of the mechanism of action of the enzyme. © 2019 IUBMB Life, 71(5):643–652, 2019