bluuebunny/crossref_metadata_2025_split huggingface dataset:
STANDARD CONSTITUTIONAL CATALOG OF PRINCIPLES OF JUDICIAL AUTHORITY IN THE CIS COUNTRIES
Authors: P. Treskov Aleksej , V. Aristov Evgeniy , E. Novikova Alevtina , A. Solovyev Andrey , D. Khlebnikov Aleksandr 
Published: May 2019

Purpose of Study: The present paper presents the results of a comparative legal analysis of constitutions of the CIS-member states in order to identify a standard catalog of judicial power principles in them, considering their interpretation as a set of fundamental principles determining the institutional and procedural aspects of judicial power. There is a lack of unity in the institutional and procedural aspects of the considered fundamental ideas together with a unified approach to the formation of a principles catalog for the judiciary in the focus group of constitutions.
Methodology: The present study was based on a rational approach to the disclosure of legal phenomena and processes, using general (system, logical, analysis and synthesis) scientific and private scientific methods. Among the latter are the formal legal, linguistic legal, comparative legal, collectively used to identify the judiciary principles.
Results: The identified standard list of constitutional principles of the judiciary in the CIS countries is presented. It includes the justice administration only by the court, organization legality and judiciary activities, prohibition of creation of emergency courts, independence, interaction, inadmissibility of interference with judiciary implementation, openness, competitiveness and equality of the parties, the state language of legal proceedings, cooperation and unity of procedure, court decisions, and state funding of courts
Implications/Applications: The comparative legal analysis, with a unified approach to the formation of the list of principles of the judiciary in the focus group of Constitutions, the lack of unity in institutional and procedural aspects of the fundamental ideas can be still stated. We believe that this discrepancy mediates the integration of the considered principles in the judiciary’s framework.
An exploration of the ‘African (Union Commission’s) perspective’ of quality and quality assurance in higher education: Latent voices in the African Quality Rating Mechanism (AQRM)
Authors: Nabaho Lazarus , Turyasingura Wilberforce 
Published: May 2019

Quality assurance of African higher education is at the top of the region’s development agenda. Prompted by the imperative to enhance the quality of higher education, the Africa Union Commission is implementing the African Quality Rating Mechanism (AQRM). The AQRM is a continental tool that affords higher education institutions an opportunity to conduct self-assessment and compare their performance against similar institutions based on a set of common criteria. The mechanism is envisaged to engender institutional cultures of quality and enhance the quality of African higher education. However, a dearth of knowledge exists about the latent notions of quality in higher education that the AQRM aims to assure and the implicit institutional-level quality assurance practices in the AQRM. Therefore, this interpretivist article, based on a review of the AQRM survey questionnaire, answered the following research question: What notions of quality in higher education and the institutional-level quality assurance practices are inherent in the quality standards of the AQRM survey questionnaire? The findings revealed that quality as fitness for purpose and exceptional are the notions of quality in higher education in the AQRM. Nevertheless, fitness for purpose is the dominant notion of quality and this symbolises an imperative to re-direct higher education to serve social and economic ends. Distinguished (excellent) teacher awards, applied research excellence awards, staff professional development, tracer studies, external examination, and the involvement of key external stakeholders in programme development are the latent institutional-level quality assurance practices in the AQRM. These quality assurance practices are in sync with the notions of quality and aim at bridging the gap between the academy and the labour market. Methodologically, the AQRM survey questionnaire is devoid of benchmarks to inform the rating, and quality assurance practices such as student evaluation of teaching, peer observation of teaching and moderation of examination items are unnoticeable in the survey questionnaire.Received: 28 December 2018Accepted: 19 April 2019Published online: 29 May 2019
FATTY ACID COMPOSITION OF SERUM LIPIDS IN PATIENTS WITH DECOMPENSATED TYPE 1 DIABETES MELLITUS DEPENDING ON THE DIABETIC KETOACIDOSIS SEVERITY
Authors: Mukha N. V. , Govorin A. V. , Perevalova E. B. , Zajtsev D. N. 
Published: May 2019

Summary. In diabetic ketoacidosis, significant metabolic disorders develop in all organs and tissues, including the myocardium. The main energy substrate in the myocardium are fatty acids.The objective was to study the fractional composition of serum lipids in patients with T1DM, complicated by diabetic ketoacidosis, depending on the severity ketoacidosis.Materials and methods. Determination of fatty acid spectrum of serum lipids was carried out in the following groups of patients: 68 patients with compensated type 1 diabetes mellitus (group 1), 54 patients with type 1 diabetes complicated by mild ketoacidosis (group 2); and 42 patients with diabetes mellitus complicated by moderate and severe ketoacidosis (3 group). Extraction of lipids from serum was performed according to the method developed by J. Folh et al. (1957), after which methylation of fatty acids was carried out according to the method proposed by K.M. Sinyak et al., with subsequent analysis using the Crystal-2000M gas chromatograph (Russia).Results. All patients with type 1 diabetes mellitus compared with a group of healthy individuals showed an increase in the total content of saturated fatty acids, a decrease in the total concentration of unsaturated fatty acids, as well as an increasing in the ratio of saturated / unsaturated fatty acids. At the same time, a significant difference between the studied groups was revealed. The most pronounced changes were found in the group of patients with type 1 diabetes mellitus complicated by moderate to severe ketoacidosis.Conclusions. These changes develop as part of a general systemic metabolic disorder in a given cohort of patients.
On the Tuning Parameter Selection in Model Selection and Model Averaging: A Monte Carlo Study
Authors: Xiao Hui , Sun Yiguo 
Published: May 2019

Model selection and model averaging have been the popular approaches in handling modelling uncertainties. Fan and Li(2006) laid out a uniﬁed frame work for variable selection via penalized likelihood. The tuning parameter selection is vital in the optimization problem for the penalized estimators in achieving consistent selection and optimal estimation. Since the OLSpost-LASSO estimator by Belloni and Chernozhukov (2013), few studies have focused on the ﬁnite sample performances of the class of OLS post-penalty estimators with the tuning parameter choice determined by diﬀerent tuning parameter selection approaches. We aim to supplement the existing model selection literature by studying such a class of OLS post-selection estimators.
Inspired by the Shrinkage Averaging Estimator (SAE) by Schomaker(2012) and the Mallows Model Averaging (MMA) criterion by Hansen (2007), we further propose a Shrinkage Mallows Model Averaging (SMMA) estimator for averaging high dimensional sparse models. Based on the Monte Carlo design by Wang et al. (2009) which features an expanding sparse parameter space as the sample size increases, our Monte Carlo design further considers the eﬀect of the eﬀective sample size and the degree of model sparsity on the ﬁnite sample performances of model selection and model averaging estimators. From our data examples, we ﬁnd that the OLS post-SCAD(BIC) estimator in ﬁnite sample outperforms most of the current penalized least squares estimators as long as the number of parameters does not exceed the sample size. In addition, the SMMA performs better given sparser models. This supports the use of the SMMA estimator when averaging high dimensional sparse models.
Improving recruitment to a study of telehealth management for COPD: a cluster randomised controlled study-within-a-trial (SWAT) of a multimedia information resource
Authors: Jolly Kate , Sidhu Manbinder , Madurasinghe Vichithranie , Bower Peter 
Published: May 2019

Abstract
Background Good quality information is critical for valid informed consent to trials, but current paper-based consent procedures are potentially unwieldy and can be difficult to comprehend, which may deter people from participating. Multimedia resources may be able to provide more accessible and user-friendly information. We aimed to test whether offering access to a multimedia information resource alongside standard, printed patient information impacted on recruitment rates, by conducting a pragmatic ‘study within a trial’ (SWAT) embedding a trial of a multimedia resource within an existing trial. Methods The PSM COPD study involved people with mild symptoms of chronic obstructive pulmonary disease (COPD) recruited from primary care being randomised to a nurse-delivered telephone health coaching intervention, or usual primary care. For the SWAT of recruitment procedures, practices recruiting participants were cluster randomised to use either the standard printed patient information materials or standard printed patient information materials with access to a multimedia information resource. The multimedia resource was developed by PPI contributors and researchers, and included study-specific information (e.g. study purpose, risks), and generic information about trials (e.g. confidentiality, randomisation). We developed a list of components and used animations as well as video clips of patients discussing their experiences of participation, matched to these components. The primary outcome was the proportion of participants randomised. Results 9.6% of those receiving standard printed patient information materials and access to the multimedia information resource were recruited, compared to 10.8% in those receiving standard printed materials alone (OR = 0.844, 95% CI 0.58 to 1.22). We also found no effects on the proportion of people response to the invitation (odds ratio1.02 95% CI 0.79 to 1.33) or retention in the trial at 6 and 12 months after randomization (odds ratios 0.84, 95% CI 0.57 to 1.22 and 0.80, 95% CI 0.54 to 1.18 respectively.) Conclusions The study suggests no benefits of access to a multimedia information resource alongside patient information materials on recruitment. This may reflect the limited engagement of patients with the multimedia resource. Further uses of multimedia resources will need to explore how content can be explicitly matched to user needs and preferences and methods to encourage engagement to see if effects can be enhanced. More SWATs of multimedia into ongoing trials will provide a more precise estimate of effect, and explore further how effects vary by trial context and recruitment process, intervention, and patient population. Trial Registration: Current controlled trials ISRCTN 06710391 (21/11/2013) SWAT registration SWAT 23: Systematic Techniques for Assisting Recruitment to Trials (MRC START) (11/01/2012).
Impact of PReOperative Midazolam on OuTcome of Elderly patients (I-PROMOTE): study protocol for a multicentre randomised controlled trial
Authors: Kowark Ana , Rossaint Rolf , Keszei András P. , Bischoff Petra , Czaplik Michael , Drexler Berthold , Kienbaum Peter , Kretzschmar Moritz , Pühringer Friedrich , Saller Thomas , Schneider Gerhard , Soehle Martin , Coburn Mark , group I-PROMOTE study 
Published: May 2019

Abstract
Introduction
Premedication with benzodiazepines in surgical patients became questionable regarding risk-benefit ratio and lack of evidence. Though, preoperative benzodiazepines might alleviate preoperative anxiety, a higher risk for adverse events is described, particularly for elderly patients (≥65 years). Several German hospitals already withhold benzodiazepine premedication from elderly patients, though evidence is lacking.
The patient-centred outcome global postoperative patient satisfaction is recognized as a substantial quality indicator of the anaesthesia care incorporated by the American Society of Anesthesiologists. Therefore, we aim to assess, whether the postoperative patient satisfaction after premedication with placebo compared to the preoperative administration of 3.75 mg midazolam in elderly patients differs.
Methods
This study is a multicentre, randomised, placebo-controlled, double-blinded, two-arm parallel, interventional trial, conducted in 9 German hospitals. In total 614 patients (≥65-80 years of age) undergoing elective surgery with general anaesthesia will be randomised to receive either 3.75 mg midazolam or placebo.
The primary outcome (global patient satisfaction) will be assessed with the validated EVAN-G questionnaire on the first postoperative day. Secondary outcomes will be assessed until the first postoperative day and 30 days after surgery, respectively. They comprise among others: functional and cognitive recovery, postoperative delirium, health-related quality of life assessment, and mortality or new-onset of serious cardiac or pulmonary complications, acute stroke, or acute kidney injury.
Analysis will adhere to the intention-to-treat principle. The primary outcome will be analysed with the use of mixed linear model including treatment effect and study centre as factors and random effects for blocks. Exploratory adjusted and subgroup analyses of the primary and secondary outcomes with regard to gender effects, frailty, pre-operative anxiety level, patient demographics and surgery experience will be performed in addition.
Discussion
This, to the best of our knowledge, is the first study analyzing patient satisfaction after premedication with midazolam in elderly patients. In conclusion, this study will provide high quality data for decision-making process regarding premedication in the elderly surgical patients.
Assessment of Antiretroviral therapy Initiation among pregnant Women under Option B+ Approach; Viral Load and CD4 Count Outcomes in selected Hospitals of West Zone Oromia, Ethiopia: Quantitative Prospective Cohort Study Design
Authors: Demissie Dereje Bayissa , Bulto Gizachew Abdissa , Mekuria Wagi Tosisa , Dufera Fikru Negassa 
Published: May 2019

Abstract
Abstract
Background: Antiretroviral therapy (ART) is effective for elimination of mother-to-child transmission (eMTCT) of human immunodeficiency virus (HIV) infection, reducing infant mortality and ensuring maternal virologic suppression. While pregnant women require lifelong ART immediately they test HIV positive (“test and treat”) under Option B+ programs, eMTCT programs face challenges and information on the relationship between the time to ART initiation following HIV testing and treatment outcomes is limited in Ethiopia
Methods: A quantitative prospective cohort design was employed to conduct the study. Five randomly selected Hospitals providing Option B+ services with routine viral load assessment by Oromia regional Laboratory (ORL) from January 2016 to January 2017 was randomly selected. Bivariate and multivariable analyses were conducted to determine factors affecting the time to ART initiation following an HIV test and logistic regression used to determine the correlation between time and treatment outcomes.
Results: The study results produced and evidence of a mean VL (copies/ml) of 197.27 copies/ml.
Respondents that were on ART for a shorter period ≤37 months had the least proportion of women 31% were suppressed with VL<1000 copies/ml compared to those on ART for >38 months (58.7%) were suppressed. The median (IQR) CD4 count change or difference among women that had initial and last CD4 was 581 cells/μl and mean of current CD4 count 629.17ceels/ml3 and more than 85.3% had increase CD4 count. Therefore, in this study identified that factors associated with viral load response were poor /fair adherence missing doses in the past month, missing appointments, baseline CD4 and maternal months on ART were statistically significant among HIV positive pregnant women that initiated lifelong ART on option B+ in Ethiopia.
Conclusion: The study results demonstrated that HIV positive pregnant women Study results indicate that majority of the respondents 89.7% were suppressed of which 80.3% were undetectable (VL= 0 copies /ml3 and 85.3% had increased CD4 count and 10.3% were not suppressed (VL >1000 copies/ml). Therefore, strategies aimed at improving adherence among women on option B+ are to ensure that these women achieve adequate immunological outcomes.
Keywords: ART Initiation Pregnant Women Option B +, Viral Load, CD4 Count
A novel miniature transposon-like element discovered in the coding sequence of a gene that encodes for 5-formyltetrahydrofolate in wheat
Authors: Keidar-Friedman Danielle , Domb Katherine , Kashkush Khalil 
Published: May 2019

Abstract
Background: Transposable elements (TEs) comprise over 80% of the wheat genome and usually possess unique features for specific super-families and families. Nevertheless, the role of TEs in wheat evolution and reshaping the wheat genome remains largely unclear. Results: In this study, we discovered a miniature (307 bp in length) TE-like sequence in exon 6 of a gene that encodes for 5-formyltetrahydrofolate, in two accessions of wild emmer wheat (T. turgidum ssp. dicoccoides) and has interfered with the gene translation by creating a shorter reading frame as a result of a stop codon. The sequence that was termed Mariam, does not show any structural similarity to known TEs. It does not possess terminal inverted repeats (TIRs) that would allow us to assign this element to one of the TIR DNA super-families, and it does not possess characteristic features of SINE, such as a Pol-III promotor or a poly-A tail. In-silico analysis of five publicly available genome drafts of Triticum and Aegilops species revealed that Mariam element appears in a very law copy number (1- 3 insertions) in diploid wheat species and ~12 insertions in tetraploid and hexaploidy wheat species. In addition, Mariam element was found to be unique to wheat, as it was not found in other plant genomes. The dynamic nature of Mariam in the wheat genome was assessed by site-specific PCR analysis and revealed that it retained activity in wild emmer populations in a population-specific manner.
Conclusions: This study provides additional insight into the evolutionary impact of TEs in wheat.
Identification, expression analysis, and potential roles of microRNAs in the regulation of polysaccharide biosynthesis in Polygonatum cyrtonema Hua
Authors: Ma Kelong , Zhang Shengxiang , Peng Daiyin , Wang Chenkai , Shi Yuanyuan , Yang Qingshan , Wu jiawen , Huang Luqi 
Published: May 2019

Abstract
Background: MicroRNAs (miRNAs) are a group of endogenous small non-coding RNAs with important roles in plant growth, development, and metabolic processes. Polygonatum cyrtonema Hua (P. cyrtonema) is an important Chinese traditional medicinal herb with broad pharmacological functions, and polysaccharides are the main biological substance accumulated in the P. cyrtonema rhizome. However, regulation of the process of polysaccharide biosynthesis in P. cyrtonema remains largely unknown.
Results: To elucidate the miRNAs and their targets involved in polysaccharide biosynthesis in P. cyrtonema, four small RNA libraries were constructed from flower, leaf, rhizome, and root tissues and sequenced. A total of 69 conserved and 5 novel miRNAs were identified, of which 6 miRNAs (miR156a-5p, miR156f-5p, miR395a_5, miR396a-3p, miR396g-3p, and miR397-5p_1) were down-regulated and 7 miRNAs (miR160, miR160h_1, miR160e-5p, miR319b_1, miR319_1, miR319c-5p_3, and miR319c_1) were up-regulated in rhizomes compared with flower, leaf, and root tissues. Bioinformatics analysis showed that the predicted targets of these miRNAs were mostly transcription factors and functional genes enriched in metabolic and secondary metabolite biosynthetic pathways, and 7 genes and their paired miRNAs were identified in carbohydrate metabolism. qRT-PCR expression analysis demonstrated that 6 miRNAs and their targets involved in carbohydrate metabolism were existed a negative correlation in. P. cyrtonema tissues. MiR396a-3p and one of its target genes, abfA, were possibly involed in polysaccharide biosynthesis pathway.
Conclusions: This is the first report on the identification of conserved and novel miRNAs and their potential targets in P. cyrtonema, thus providing molecular evidence for the role of miRNAs in the regulation of polysaccharide biosynthesis in P. cyrtonema.
Guest Workers – From Their Own Perspective. Narratives About Life and the Socio-Economic Position of Migrant Workers
Authors: Antonijević Dragana , Banić Grubišić Ana , Krstić Marija 
Published: May 2019

Based on fieldwork conducted in Eastern Serbia (Knjaževac and Kučevo with surrounding regions), this paper analyzes the life stories of migrant workers as material crucial for anthropological and folkloristic research into experiences, values and attitudes of the members of a certain culture. The term “guest worker” (ser. gastarbajter, i.e. ger.gastarbeit) was used to designate temporary migrants who served as labor at the time of the reconstruction of Western Europe after World War II. A large number of migrant workers decided to stay in the host countries, and work migrations are still a common occurrence today. Based on the life stories of guest workers, in this paper we will attempt to map out the specific characteristics of different waves of migration. While all the waves of migration had a common cause – the desire for a better life and material stability – there were certain additional motives which depended on the political and socio-economic conditions in the home country. Furthermore, we are interested in the process of acculturation in different host countries, focusing on the differences in social policy regarding immigrants, the geographic distance from Serbia and the number of compatriots in the host country. Finally, we will address the narratives of guest workers who have returned, focusing on the reasons they decided to come back to their home country and the ways in which they settled down after their return.
Collections of the Museum of Kemerovo State University as a Basis for Scientific Reconstruction of the Teleut Women’s Costume
Authors: Bogolepova L. Z. , Belousova N. A. 
Published: May 2019

The research features the historical and cultural heritage of the Teleuts, an indigenous people of Kuzbass, in particular their national costumes stored in the funds of the museum «Archeology, Ethnography, and Ecology of Siberia» (Kemerovo State University). The museum collections form a basis for scientific historical reconstruction of women’s Teleut costume. The paper describes authentic ethnographic items of the main collection and the archives: various collections, field notebooks, expedition diaries, and reports made by scientists of the university, as well as photographs, videos, slides, and sketches. It is the first time the documentary funds have been introduced into scientific use. The research involved the prosopographic database of the scientists who donated valuable collections on the material and spiritual culture of the Teleuts, as well as museum collections of the departments of ethnography and history. The authors also described historical and ethnographic heritage collected by the scientists who organized expeditions in 1960s – late 1990s and donated their collections to the museum. The authors evaluated the contribution the scientists made to the studies of the Teleut culture. In addition, the article introduces an acquisition technique that would guarantee the authenticity of the items related to the Teleut culture.