bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sobre el análisis de la pobreza urbana y el medio ambiente: una visión socioecológica/ On the analysis of urban poverty and the environment: a socio-ecological view
Authors: London Silvia 
Published: September 2018

El estudio de los sistemas económicos se caracteriza principalmente por el análisis de los aspectos productivos y distributivos de una sociedad. Al incorporar la dimensión ambiental al análisis económico, la rama de la Economía Ambiental se concentra en subsanar fallas de mercado para continuar con valoraciones economicistas costo-beneficio. Como crítica a esta visión, la Economía Ecológica basa sus estudios en una perspectiva sistémica. Por otro lado, el enfoque de autoorganización y gobernanza de Elinor Ostrom analiza la utilización de los recursos medioambientales (naturales) en forma sostenible. Combinado con el enfoque cualitativo proveniente de La Prospective, permite avanzar en la definición y el estudio de los sistemas socioecológicos. A pesar de estos avances, en el tratamiento de los problemas medioambientales y la pobreza en el entorno urbano, el análisis económico parece estar limitado a enfoques cuantitativos puntuales de costo-beneficio, en los que la posibilidad de gobernanza y políticas bottom-up se ignoran. Para avanzar en esa dirección, en este artículo se propone una discusión conceptual sobre el impacto ambiental de la pobreza urbana, a partir del concepto de sistema socioecológico en un entorno urbano.
Abstract
The study of economic systems is mainly characterized by the analysis of the productive and distributive aspects of a society. By incorporating the environmental dimension to the economic analysis, the environmental economics branch focuses on remedying market failures to continue with cost-benefit approaches. As a critique of this vision, the ecological economics bases its studies on a systemic perspective. On the other hand, the self-organization and governance approach of Elinor Ostrom analyzes the sustainable use of environmental resources (natural) in a sustainable way. Combined with the prospective analysis, it allows progress in the comprehension of socio-ecological systems. Despite these advances, the treatment of environmental problems and poverty in an urban environment seems to be limited to specific quantitative cost-benefit approaches, in which the possibility of governance and bottom-up policies is ignored. To move in that direction, we propose a conceptual discussion on the environmental impact of urban poverty, based on the concept of socio-ecological system in an urban space.
Uso de Microalgas para Produção de Biodiesel
Authors: Carneiro Gillianne Assis , Silva Josiano Josiel Rodrigues , Oliveira Gisely de Assis , Pio Fernanda Paula Bicalho 
Published: September 2018

A maioria das demandas energéticas da sociedade ainda são atendidas pelos combustíveis de origem fóssil. Porém, essa fonte vem sendo substituída por outras renováveis, menos agressivas ao meio ambiente e com melhor custo/benefício. Como exemplo, podemos mencionar os biocombustíveis produzidos a partir de plantas oleaginosas e microrganismos, que são capazes de substituir os derivados do petróleo com eficiência equivalente. Graças a sua elevada produção de lipídios, as microalgas, cujo diâmetro não ultrapassa 2 mm, são objeto de estudos e estão sendo aplicadas na produção de biocombustíveis, em especial, do biodiesel, sendo que, cerca de 150 espécies de microalgas são usadas comercialmente. O objetivo deste trabalho foi realizar uma revisão de literatura sobre a produção de biodiesel a partir de microalgas. Este estudo é do tipo teórico-conceitual, visto que foi elaborado a partir da realização de pesquisas na literatura nacional e internacional sobre a produção de biocombustíveis a partir de microalgas, além da consulta a órgãos governamentais e legislações pertinentes. Ademais, pretende-se apresentar as principais técnicas de cultivo e de produção, bem como as principais vantagens e desvantagens da utilização das microalgas para produção de biodiesel. A partir da problemática ambiental e da redução das reservas fósseis faz-se necessário o investimento em fontes alternativas, sendo o biodiesel produzido a partir de microalgas uma opção a ser considerada e aperfeiçoada para produção e utilização em escala comercial.
Qualidade de Vida no Trabalho: Um estudo realizado em uma organização de coleta de resíduos não perigosos
Authors: Pereira Grasiele Cabral , Romão Leandro Nunes 
Published: September 2018

O artigo visa elaborar um diagnóstico de uma organização de coleta de resíduos não perigosos, onde se busca analisar quais os fatores determinantes da qualidade de vida no trabalho para os colaboradores da organização. Nadler e Lawler (1983) afirmam que a Qualidade de Vida no Trabalho é uma maneira de pensar nos indivíduos, no trabalho e na própria empresa. Esta pesquisa caracteriza-se como exploratória, descritiva e quantitativa, com o uso de estatística e aplicação de um questionário objetivando identificar a Qualidade de Vida no Trabalho da empresa em questão. O questionário aplicado foi criado por meio da interpretação e análise das oitos dimensões de QVT apresentadas por Walton (1973). Quanto à população, utilizou-se uma amostra intencional compreendendo os funcionários do setor administrativo. Quanto às análises realizadas a partir dos gráficos, constatou-se que a organização transmite aos seus funcionários uma boa qualidade de vida, pois se obteve um pequeno percentual de respondentes que não concordavam em parte, ou não concordavam com algumas das afirmativas indagadas.
O Teatro e Vygotsky
Authors: Paz Ana Liziane Araújo da , Ramalho Dayana Tavares de Oliveira , Pinheiro Fernanda Karla Augusta da Silva , Freitas Giovana de Oliveira , Costa Leylane de Oliveira , Andrade Lídia da Silva , Fernandes Paula Franssinette da Silva Barbosa , Fonseca Géssica Fabiely 
Published: September 2018

As funções psicológicas superiores interferem nos processos de internalização e desenvolvimento psicológico do indivíduo. Contudo, essas funções não se instituem sozinhas, mas pela interação social. Pensando nisso, o teatro na perspectiva de Lev Vygotsky é concebido como uma atividade coletiva que pode agir na Zona de Desenvolvimento Proximal (ZDP), unindo as aprendizagens consolidadas de cada sujeito com diferentes estratégias de mediação, criando novas ZDPs. Quanto aos aspectos metodológicos, foi aplicada uma oficina teatral, baseada nos jogos propostos por Viola Spolin, durante aproximadamente três horas e meia, com 15 alunos do 50 ano (idade aproximada: 9-11 anos) do Ensino Fundamental I da escola particular Complexo Educacional Parque Dunas, localizada na Zona Norte de Natal. Os resultados evidenciam o papel da mediação pedagógica para o desenvolvimento das capacidades de representação simbólica e teatral das crianças no contexto escolar e as habilidades discentes no que se refere a imaginação e criatividade. O estudo conclui, assim, que é de extrema importância o incentivo ao trabalho em equipe e à autonomia, que podem ser proporcionados pelas artes, como o teatro, que são ferramentas riquíssimas dentro de sala de aula e notáveis para o desenvolvimento cognitivo dos alunos.
Phenotypic and Genotypic Analysis of Gentamicin, Penicillin, Methicillin, Vancomycin, Linezolid and Tetracycline Resistance in Clinical Isolates of Staphylococcus aureus
Authors: ORHAN Zerife , KAYIŞ Arzu , KAYA Esra , ARAL Murat 
Published: September 2018

In this study, it was aimed to investigate the resistance rates of gentamicin, penicillin, methicillin, vancomycin, linezolid and tetracycline by phenotypic and genotypic methods in Staphylococcus aureus isolates and to determine plasmid content. Between the months of January and September in 2015, 100 clinical isolates of S. aureus were obtained from different samples such as wound, blood, urine. The automated bacteria identification and antibiotic susceptibility system (BD PhoenixTM, Sparks, MD, USA) was used to determine of antibiotic sensitivities. The resistance to methicillin was also investigated by Kirby-Bauer disc diffusion method using a 30 μg cefoxitin disc. The presence of aac(6’)/aph(2’’), blaZ, mecA, femA, vanA, vanB, cfr, tetK and tetM genes related to antibiotic resistance was investigated by PCR amplification in all isolates. Plasmid DNAs were isolated by using a Thermo Scientific GeneJET Plasmid Miniprep Kit. The cefoxitin resistance of S.aureus isolates, identified according to the results of disk diffusion and automated system, was calculated as 19%. Vancomycin and linezolid resistance were not observed in isolates while gentamicin 2%, penicillin 100%, methicillin 19%, tetracycline 18% resistance were identified using the automated system. According to the results of molecular analysis aac(6’)/aph(2’’), blaZ, mecA, femA, tetK and tetM genes frequencies were determined as 2%, 100%, 19%, 100%, 17% and 3% respectively, but vanA, vanB and cfr genes were not amplified by PCR. In order to determine the relationship between antibiotic resistance and plasmid presence, plasmids were isolated from identified bacterial isolates. It is found that most of bacterial isolates (79%) contain different numbers plasmids. Rapid and reliable method for antibiotic susceptibility is important to determine the appropriate therapy decision. PCR can be used for confirmation of the results obtained by automated system or could be used as an alternative diagnostic method in the routine diagnosis for rapid, sensitive, and specific detection of MRSA associated antibiotic resistance genes.
Estimation of Nitrogen Levels By Remote Sensing Method in Alfalfa (Medicago sativa L.)
Authors: ÖZYİĞİT Yaşar , BİLGEN Mehmet 
Published: September 2018

The aim of this study was to obtain spectral reflectance values by using
remote sensing method in alfalfa plant and to estimate nitrogen levels by using
these values. The treatments were carried out in both field and greenhouse
conditions. Different nitrogen, phosphorus and potassium
doses were applied to plots in the field and pots in greenhouse. Spectral
reflectance measurements were made at both the canopy (general) level and the
single leaf level when the plants were in pre-flowering stage. Reflectance measurements were undertaken using a portable
spectroradiometer measuring the wavelength range of 325-1075 nm of the
electromagnetic spectrum. Plant probe with artificial light source and leaf
clip were used for leaf measurements. Statistical analyses were conducted using
stepwise regression analysis
implemented in MINITAB-13 statistical program. As a result of the study,
significant relationships (Field-canopy: 0.94, Field-leaf: 0.23,
Greenhouse-canopy: 0.55, Greenhouse-leaf: 0.92) were determined between
the nitrogen levels in the plant and the reflectance values. Also results showed that
changes in nitrogen levels affect reflectance in the visible region (400-700
nm) of the spectrum. When the wavelengths were evaluated separately, it was observed
that the wavelengths of the blue, red and near infrared regions, which are
important for photosynthesis, can be used to estimate the nitrogen levels.
Circulatory Condition in Kidney Patients with Pururlent Pyelonephritis
Authors: Ananev Vladimir Alexandrovich , Lubyansky Vladimir Grigorievich 
Published: September 2018

The article provides up-to-date statistics on the prevalence of purulent pyelonephritis in Russia, shows the pathogenesis of purulent pyelonephritis in terms of circulatory disorders in the kidney for example 23 patients operated personally by the author in Urology conditions of the Altai Krai hospital on his own technique in the period 2016 by 2017. Morphological studies were carried out in the Department of pathologic Anatomy. Assess the morphological distortion in the kidney with significant changes in the mikrocirkuljatornom vein during the operation of the apostem zone, perifokalnogo zone of inflammation around 1 cm from the pockets of destruction and of apparently healthy sections of kidney the same kidney parenchyma jelektronnomikroskopicheskim method. Additionally investigated plots tissues of the kidneys removed due to have resulted them irreversible destructive changes.
Irreversible development of acute purulent pyelonephritis associated with renal tissue ischemia and to achieve good results in the treatment of patients, appropriate action must be taken to restore the lost blood flow.
Pelatihan Pengenalan Aplikasi Pembelajaran Edmodo bagi Mahasiswa Universitas Kanjuruhan Malang
Authors: Mafulah Siti , Wilujeng Trisno Tunggal Rahayu 
Published: September 2018

In accordance with the vision of Universitas Kanjuruhan Malang as excellent campus in 2025 and excellent in education field in 2020, it is obviously important to do some actions. One of the ways is improving education quality through e-learning. The aims of this community service are 1) giving knowledge what kinds of application which can be applied in teaching learning process, 2) training the students in making Edmodo account, 3)knowing the students responses toward the use of Edmodo in teaching learning process. Method used in this activity is training. The steps were 1) introduced application that can be alternative media in teaching learning process, 2) introduced Edmodo as media, 3)workshop in making and joining group class, 4) simulation the use of Edmodo in small class and 5) evaluation. The finding of this activity was 85% students having good sense in applying Edmodo at class and Emodo is ready to be applied in class.
The Circadian PER2 Enhancer Nobiletin Reverses the Deleterious Effects of Midazolam in Myocardial Ischemia and Reperfusion Injury
Authors: Oyama Yoshimasa , Bartman Colleen Marie , Gile Jennifer , Sehrt Daniel , Eckle Tobias 
Published: September 2018

Background:
Recently, we identified the circadian rhythm protein Period 2 (PER2) in robust cardioprotection
from myocardial ischemia (MI). Based on findings that perioperative MI is the most common major
cardiovascular complication and that anesthetics can alter the expression of PER2, we hypothesized that an anesthesia
mediated downregulation of PER2 could be detrimental if myocardial ischemia and reperfusion (IR) would
occur.

Methods:
and Results: We exposed mice to pentobarbital, fentanyl, ketamine, propofol, midazolam or isoflurane
and determined cardiac Per2 mRNA levels. Unexpectedly, only midazolam treatment resulted in an immediate
and significant downregulation of Per2 transcript levels. Subsequent studies in mice pretreated with midazolam
using an in-situ mouse model for myocardial (IR)-injury revealed a significant and dramatic increase in infarct
sizes or Troponin-I serum levels in the midazolam treated group when compared to controls. Using the recently
identified flavonoid, nobiletin, as a PER2 enhancer completely abolished the deleterious effects of midazolam
during myocardial IR-injury. Moreover, nobiletin treatment alone significantly reduced infarct sizes or Troponin I
levels in wildtype but not in Per2-/- mice. Pharmacological studies on nobiletin like flavonoids revealed that only
nobiletin and tangeritin, both found to enhance PER2, were cardioprotective in our murine model for myocardial
IR-injury.

Conclusion:
We identified midazolam mediated downregulation of cardiac PER2 as an underlying mechanism
for a deleterious effect of midazolam pretreatment in myocardial IR-injury. These findings highlight PER2 as a
cardioprotective mechanism and suggest the PER2 enhancers nobiletin or tangeritin as a preventative therapy for
myocardial IR-injury in the perioperative setting where midazolam pretreatment occurs frequently.
Protective Role of Endogenous PACAP in Inflammation-induced Retinal Degeneration
Authors: Vaczy Alexandra , Kovari Petra , Kovacs Krisztina , Farkas Kinga , Szabo Edina , Kvarik Timea , Kocsis Bela , Fulop Balazs , Atlasz Tamas , Reglodi Dora 
Published: September 2018

Purpose: Pituitary adenylate Cyclase-Activating Polypeptide (PACAP) is a neuroprotective peptide
that has been shown to exert protective effects in different models of neurodegenerative diseases, including retinal
degenerations. Data obtained from PACAP-deficient (PACAP KO) mice provide evidence that endogenous
PACAP has a neuroprotective role in different pathologies. PACAP KO mice show enhanced sensitivity to different
insults, such as oxidative stress, hypoxia and inflammation. The aim of the present study was to investigate
the protective effects of endogenous PACAP in retinal inflammation.

Methods:
Endotoxin-induced eye inflammation was induced by intraperitoneal injection of lipopolysaccharide
(LPS) in PACAP KO and wild-type (Wt) mice. After LPS treatment, retinas were processed for histological examination.
To detect the alterations of different proteins and cytokines, immunohistochemical, western blot and
cytokine array were used. We also performed dark-adapted electroretinography (ERG) to detect the functional
differences.

Results:
The thickness of nearly all layers was significantly less in LPS-injected PACAP KO mice compared to
Wt animals. Increased expression of Glial Fibrillary Acidic Protein (GFAP) was induced in Müller glial cells
after LPS treatment, which was more intense in PACAP KO mice. The levels of pAkt and pGSK were decreased
in PACAP KO group during inflammation. LPS treatment significantly increased cytokines (sICAM-1, JE,
TIMP-1) in both treated groups, but it was more expressed in PACAP KO animals. Furthermore, ERG responses
were disturbed after LPS injection in PACAP KO mice.

Conclusion:
Our results showed that endogenous PACAP has a protective role in LPS-caused retinal inflammation.
Association of High Levels of Spot Urine Protein with High Blood Pressure, Mean Arterial Pressure and Pulse Pressure with the Development of Diabetic Chronic Kidney Dysfunction or Failure among Diabetic Patients. Statistical Regression Modeling to Predict Diabetic Proteinuria
Authors: Ahmed Aziz Kamran M. 
Published: September 2018

Introduction:In research elevated Blood Pressure (BP) has been demonstrated to be a risk for the development of nephropathy and chronic renal disease (CKD) Or Diabetic Kidney Disease (DKD) among diabetics. However, no study has find correlation for the spot urine protein (UPr) excretion with elevated BP, Pulse Pressure (PP) and mean arterial pressure MAP). This technique was invented in the current study.Methods:10,270 were recruited for more than 12 years. Demographically, 43%, 38%, and 16% showed hypertension, nephropathy and chronic renal disease, respectively. UPr demonstrated significant correlations with systolic BP (SBP) and diastolic BP (DPB), MAP and PP (p < 0.0001 for all). SBP, DBP, PP and MAP, UPr were observed to be higher among the groups with nephroaphty and CKD/DKD with highly significant p-values (all p < 0.05). With logistic regression, odds ratio of hypertension (HTN) with nephropathy was observed to be 2.99 (95% CI 2.44 to 3.7; p < 0.0001); and odds ratio of HTN with CKD/DK was 7.1 (95% CI 4.3 to 11.84; p<0.0001), indicating that HTN significantly contributes to the development of nephropathy and CKD/DKD in diabetics.Results:Invented regression models for the excretion of UPr from the kidney with elevated SBP, DBP, MAP and PP were highly significant (p < 0.0001 for all); UPr = -138.6 + [1.347 × SBP] ; UPr = -93.4 + [1.62 × DBP] ; UPr = -149.5 + [1.922 × MAP] ; UPr = -41.23 +[1.541 × PP].Conclusion:Current study is the first one to introduce this technique. These invented new equations can be used by physicians to estimate protein excretion in urine at bedside and outpatients departments for monitoring proteinuria and CKD/DKD.
Antiproliferative Effects of Cynaropicrin on Anaplastic Thyroid Cancer Cells
Authors: Lepore Saverio M. , Maggisano Valentina , Lombardo Giovanni E. , Maiuolo Jessica , Mollace Vincenzo , Bulotta Stefania , Russo Diego , Celano Marilena 
Published: September 2018

Background:
The sesquiterpene lactone cynaropicrin, a major constituent of the artichoke
leaves extracts, has shown several biologic activities in many preclinical experimental models, including
anti-proliferative effects.

Objective:
Herein we evaluated the effects of cynaropicrin on the growth of three human anaplastic
thyroid carcinoma cell lines, investigating the molecular mechanism underlying its action.

Method:
MTT assay was used to evaluate the viability of CAL-62, 8505C and SW1736 cells, and flow
cytometry to analyse cell cycle distribution. Western blot was performed to detect the levels of STAT3
phosphorylation and NFkB activation. Antioxidant effects were analyzed by measuring the reactive
oxygen species and malonyldialdehyde dosage was used to check the presence of lipid peroxidation.

Results:
Viability of CAL-62, 8505C and SW1736 cells was significantly reduced by cynaropicrin in a
dose- and time-dependent way, with an EC50 of about 5 &#181;M observed after 48 h of treatment with the
compound. Cellular growth inhibition was accompanied both by an arrest of the cell cycle, mainly in
the G2/M phase, and the presence of a significant percentage of necrotic cells. After 48 h of treatment
with 10 &#181;M of cynaropicrin, a reduced nuclear expression of NFkB and STAT3 phosphorylation were
also revealed. Moreover, we observed an increase in lipid peroxidation, without any significant effect
on the reactive oxygen species production.

Conclusion:
These results demonstrate that cynaropicrin reduces the viability and promotes cytotoxic
effects in anaplastic thyroid cancer cells associated with reduced NFkB expression, STAT3 phosphorylation
and increased lipid peroxidation. Further characterization of the properties of this natural compound
may open the way for using cynaropicrin as an adjuvant in the treatment of thyroid cancer.
A Study on the Influence of the Information Characteristics of Airline Social Media on e-WOM, Brand Equity and Trust
Authors: Seo Eun-Ju , Park Jin-Woo 
Published: September 2018

Background:This study investigates the effect of three of the information characteristics of airline social media – information quantity, information credibility and information quality – on brand equity and trust through electronic Word-Of-Mouth (e-WOM).Methods:For the analysis, we surveyed 430 passengers who had used airline social media and analyzed the collected data using a structural equation.Results:The results of the analysis showed that while the information quantity and information quality of airline social media had a significant effect on e-WOM, information credibility did not have a significant effect. e-WOM had a significant effect on brand awareness and brand image. Brand image and e-WOM also had a significant effect on trust, but brand awareness did not have a statistically significant effect on trust.Conclusion:This study establishes a model for the information characteristics of social media and can be utilized as basic data to explain how airlines should manage and utilize social media information.