bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Multi-attribute Online Advertising Budget Allocation Under Uncertain Preferences
Authors: Gupta Aggarwal Anu , . Aakash 
Published: August 2018

Introduction: The present research was conducted at the University of Delhi in 2017.
Method: Websites were ranked on the basis of feedback from unbiased experts. Later, we proposed an integrated approach by combining ordered weighted averaging (owa) operator with fuzzy analytic hierarchy process (fahp) for budget allocation.
Results: A numerical example related to a company, which deals with consumer goods and wants to advertise on few e-commerce websites is discussed at the end of the paper. Budget distribution is decided by solving multi-objective maximum-dispersion-minimum-variance (mdmv) owa and fahp method.
Conclusions: The proposed methodology aids managerial decisions made by handling multiple attributes simultaneously through industry experts’ opinion, and using a simple proportional rule for allocating budget.
Originality: The conventional methods based on reach maximization, exposure or profit cannot meet the budget allocation needs of the modern advertising planning. Firstly, they do not take into consideration multiple attributes of media. Secondly, they do not incorporate the expert opinion and their preferences. To address these problems, we propose a multi-attribute method based on the advertising budget allocation method to divide the budget into individual websites. The attributes under consideration are: system quality, content quality, usage, trust, customer support, online customer feedback, and personalization.
Limitations: In this study, we used a mdmv-owa operator in fuzzy environment but in future occasions, it may be extended to intuitionistic fuzzy domain.
Diagnósticos de enfermagem do domínio atividade/repouso em pessoas vivendo com aids: transversal
Authors: Alves Reno Ribeiro Barbosa , Neto Vinicius Lino de Souza , Alves Renan Ribeiro Barbosa , Silva Bárbara Coeli Oliveira da , Santos Sueleide Cristina Dantas dos , Silva Richardson Augusto Rosendo da 
Published: August 2018

Objetivo : Identificar diagnósticos de enfermagem do domínio da atividade / repouso da Taxonomia II da NANDA-I e analisar uma associação entre os diagnósticos mais frequentes e suas características definidoras, fatores relacionados / risco em pessoas vivendo com Aids. Método : Trata-se de um estudo transversal, descritivo com abordagem quantitativa, realizado com 113 pacientes sem período de março e setembro de 2014. Para uma coleta de dados, use-se dois instrumentos validados para realização de anamnese e exame físico. Para uma elaboração dos diagnósticos segue-se ou modelo de Risner. Para uma associação utilizou-se os testes de qui-quadrado e exato de fisher. Resultados : Identificou-se 30 diagnósticos, e apenas um conjunto de experiências com seus componentes: Padrão de sono prejudicado; Fadiga; Insônia; Risco de perfusão renal ineficaz; Deambulação prejudicada; Déficit no autocuidado para o banho. Conclusão: Assim, os diagnósticos são como associações respectivas e essenciais para uma estruturação dos diagnósticos, e direcionando para as intervenções de enfermagem prioritárias.
Estratégias educativas utilizadas nos sistemas de linguagens padronizadas por enfermeiros: revisão integrativa
Authors: Melo Luciana Silva de , Figueiredo Lyvia da Silva , Pereira Juliana de Melo Vellozo , Flores Paula Vanessa Peclat , Barbosa Siqueira Marina Einstoss , Cavalcanti Ana Carla Dantas 
Published: August 2018

Objetivo: identificar as estratégias educativas utilizadas no treinamento de enfermeiros sobre processo de enfermagem com sistemas de linguagens padronizadas. Método: trata-se de uma revisão integrativa da literatura, realizada a partir das seguintes bases de dados: MEDLINE via PUBMED; CINAHL; SCOPUS e LILACS. Resultados: foram selecionados seis estudos. As estratégias empregadas foram: uso de um guia prático, workshop, grupo de estudos, registro em instrumentos padronizados, discussão de estudos de casos fictícios e reais, aulas teórico-práticas com utilização de casos clínicos e raciocínio clínico guiado. Discussão: o conhecimento produzido sobre as estratégias utilizadas para o treinamento de enfermeiros sobre processo deenfermagem, com e sem sistemas de linguagens padronizadas, ressaltaram a importância destas estratégias para a incorporação de registros com maior qualidade, por meio de quatro estudos clínicos e dois descritivos. Conclusão: as estratégias educativas utilizadas para treinamento de enfermeiros promovem melhora na implementação do processo de enfermagem com sistemas de linguagem padronizadas.
Vivenciando a parada cardiorrespiratória e óbito por familiares: estudo descritivo
Authors: Silveira Edilene Aparecida Araújo , Magalhães Ana Carolina Guimarães de , Alves Michely Izabel , Silva Vivianny Christine Marques , Oliveira Patrícia Peres 
Published: August 2018

Objetivo: compreender a vivência de familiares de pessoas que sofreram parada cardiorrespiratória e foram a óbito. Método: estudo descritivo, qualitativo, que utilizou como referencial teórico e metodológico, respectivamente, interacionismo simbólico e interacionismo interpretativo. Os dados foram coletados por intermédio de entrevista semiestruturada no domicílio de 11 familiares, no período de novembro de 2015 a junho de 2016. Resultados: a análise das narrativas evidenciou diversos sentimentos como raiva, ansiedade e esperança. Foram identificadas duas epifanias. A primeira epifania, descobrindo que o familiar morreu, teve como categorias: vivenciando o momento da PCR e recebendo a notícia. Na segunda epifania, convivendo com as mudanças imediatas, evidenciou-se as categorias: relembrando e sentindo a dor da perda e mudanças após o falecimento do familiar. Conclusão: a perspectiva interacionista permitiu melhor compreender a experiência de familiares ao aguardar o atendimento de parada cardiorrespiratória e a posterior recepção da notícia de morte de seu ente querido.
Formação audaciosa do enfermeiro-cientista
Authors: Zancheta Margareth Santos , Santos Walterlânia Silva , Felipe Ingryd Cunha Ventura , Lucchese Stephanie 
Published: August 2018

A ciência da Enfermagem inclui o manejo do pensamento crítico contemporâneo para a apropriação de inovações da tecnologia. Este aspecto é intrínseco à formação do enfermeiro e nos remete aos binômios ensino-aprendizagem, criatividade-intuição e teoria-prática. O que mais nos importa em tais avanços na configuração do novo pensamento crítico, clínico e científico? As respostas precisam ser: tudo e também. Se parecem ser respostas sucintas, vale lembrar que a Enfermagem, desde sua origem, tem seus marcos conceituais com as complexidades da realidade. Para tanto, democratizar o conhecimento sobre metodologia de pesquisa, desmistificando-a como uma prática exclusiva de poucos, resultaria em despertar a paixão pela pesquisa. Com quem? A nova geração de graduandos deve se conscientizar que no mundo atual da internacionalização da educação universitária, oportunidades existem, mas somente aqueles que estejam prontos para delas se apoderarem podem alcançar conquistas profissionais.
Characterizing Soybean Meal Value Variation across the United States: A Swine Case Study
Authors: Mourtzinis Spyridon , Borg Barton S. , Naeve Seth L. , Osthus John , Conley Shawn P. 
Published: August 2018

Core Ideas
A model that precisely estimates soybean meal value targeted for swine nutrition was developed.
A large soybean meal value range was observed among and within each state.
Minimum protein and oil content as the only soybean meal value criteria can be misleading.
Soybean [Glycine max (L.) Merr.] is the most important oilseed crop in the United States; however, the quality characteristics of the soybean meal (SBM) produced from soybean grown in various regions can vary significantly, often leading to region‐specific commodity price differentials. Currently, a fast, cost‐effective, and accurate estimation method of SBM value does not exist. Our objectives were to (i) develop a model using existing data that precisely estimates SBM value targeted for swine nutrition, (ii) quantify the swine‐specific SBM value variability within and among states and (iii) evaluate the predictive effectiveness of the model for estimating SBM value. The compositional characteristics of 8282 soybean samples from 2013 to 2016 in 29 states were determined. Assuming constant energy content, considering meal protein content and the concentrations of four essential amino acids (AA) (lysine [Lys], methionine [Met], tryptophan [Tryp], and isoleucine [Iso]) from these samples, a model that precisely estimates swine‐specific SBM value was developed. Within each state, US$17 to $66 t−1 SBM value range was estimated. A model based on combined and maturity group‐specific analysis showed that using a simple base‐line seed content of >350 g kg−1 for protein and >190 g kg−1 for oil to identify high‐quality cultivars can be misleading and that the proposed model can estimate swine‐specific SBM value more precisely, both locally and regionally. This method can also be used for other, economic important animal diets (e.g., poultry) which could help U.S. soybean producers choose high‐yielding cultivars that are more likely to produce seed with increased ration‐specific SBM value.
Spring Wheat Yields Following Perennial Forages in a Semiarid No‐Till Cropping System
Authors: Franco J.G. , Duke S.E. , Hendrickson J.R. , Liebig M.A. , Archer D.W. , Tanaka D.L. 
Published: August 2018

Core Ideas
Perennial forage effects on crop yields have mixed outcomes.
Few studies have evaluated the lasting impacts of perennial forages in no‐till crop rotations beyond the first crop year.
Five forages were evaluated over 7 yr for their effects on crop yield in a no‐till system.
Alfalfa and alfalfa–perennial grass mixtures showed the greatest promise for enhancing crop yields.
Perennial forages have the potential to diversify annual crop rotations and provide yield benefits to subsequent cash crops. Little is known about the duration of and extent to which yield benefits are observed in semiarid no‐till systems following perennial forages, which may depend on the perennial crop type and duration of the perennial phase. Five perennial forage and forage combinations, alfalfa (Medicago sativa L.; PALF), intermediate wheatgrass [Thinopyrum intermedium (Host) Barkw. & D.R. Dewey subsp. Intermedium; IMWG], switchgrass (Panicum virgatum L.; SWG), alfalfa–intermediate wheatgrass mixture (PALF+IMWG), alfalfa–switchgrass mixture (PALF+SWG), and an annual cropping system of continuous spring wheat (Triticum aestivum L.) fertilized with 67 kg ha−1 of N (CWF) were evaluated for their impacts on wheat yields in a 7‐yr study conducted near Mandan, ND. Wheat yields following 2 yr of alfalfa were comparable to CWF, and 3 and 4 yr of alfalfa, respectively, were 19 and 41% higher. After 5 yr of PALF+SWG, which was primarily comprised of alfalfa, wheat yields were 23% higher than CWF, and comparable to CWF after 3 and 4 yr in PALF+SWG. Four years in PALF+IMWG were needed to produce wheat yields comparable to CWF. Yield benefits persisted for up to 3 and 4 yr following 3 yr of PALF or 5 yr of PALF+IMWG, respectively. Overall, alfalfa and alfalfa–perennial grass mixtures showed the greatest promise for enhancing yields. These results indicate that a perennial phase of at least 2 yr is needed to provide yield benefits to subsequent no‐till annual crops.
HUBUNGAN KADAR KOLESTEROL HDL SAAT MASUK RUMAH SAKIT DENGAN LUARAN KLINIS PASIEN STROKE ISKEMIK DI RS BETHESDA YOGYAKARTA
Authors: Florence Florence , Pinzon Rizaldy Taslim , Pramudita Esdras Ardi 
Published: August 2018

Pendahuluan: Stroke merupakan salah satu penyebab utama kematian dan kecacatan di dunia. Prinsip dasar terjadinya stroke adalah adanya aterosklero- trombosis. Kadar kolesterol HDL yang tinggi dapat menjadi faktor protektif terhadap stroke iskemik. Kadar kolesterol HDL yang tinggi dapat memperbaiki luaran klinis stroke iskemik. Penelitian terdahulu masih kontroversial dan memerlukan penelitian lebih lanjut.
Metode: Penelitian ini merupakan studi prognostik dengan menggunakan
metode penelitian kohort retrospektif. Sampel didapatkan dari data rekam medis pasien di poliklinik saraf Rumah Sakit Bethesda Yogyakarta pada tahun 2013 sampai 2014. Data yang diperoleh kemudian dianalisis univariat, dilanjutkan dengan analisis bivariat dengan uji chi-square serta uji t-independen dan multivariat dengan uji regresi logistik.
Hasil: Dari 102 data rekam medis pasien stroke iskemik dengan onset < 24 jam
didapatkan 65 pasien laki-laki (63,7%) dan 37 pasien perempuan (36,3%) dengan usia terbanyak yang menderita stroke adalah usia 61-70 tahun yaitu sebanyak 36 orang (35,3%). Pasien yang memiliki kadar kolesterol HDL yang normal saat masuk rumah sakit adalah sebanyak 53 pasien (52%). Hasil analisis bivariat didapatkan variabel yang berhubungan signifikan dengan luaran klinis stroke iskemik adalah kolesterol total (RR: 0,273, 95%CI: 0,106-0,700, p: 0,005), afasia (RR: 0,256, 95%CI:
0,087-0,754,p: 0,010) dan kekuatan otot (RR: 0,344, 95%CI: 0,137-0,863, p: 0,020).
Hubungan kadar kolesterol HDL dengan luaran klinis stroke iskemik yang diukur menggunakan skor mRS didapatkan hubungan yang tidak signifikan (RR: 0,61&, 95%CI: 0,253-1,485, p: 0,276). Hasil analisis multivariat dengan regresi logistik didapatkan hasil bahwa kolesterol total dan afasia merupakan faktor independen yang mempengaruhi luaran klinis stroke iskemik.
Kesimpulan: Tidak terdapat hubungan yang signifikan antara kadar kolesterol
HDL saat masuk dengan luaran klinis stroke iskemik yang diukur dengan skor mRS.
Kata Kunci: stroke iskemik, kadar kolesterol HD/, luaran klinis, modified Rankin Scale (mRS)
TIPE KEMATIAN SEL HeLa SETELAH PAPARAN EKSTRAK ETANOLIK CURCUMA LONGA
Authors: Hutomo Suryani , Kurniawan Chandra 
Published: August 2018

Kunyit (Curcuma Zonga) merupakan tanaman yang dapat tumbuh di daerah tropis dan sub tropis. Di Indonesia, kunyit menyebar secara merata di seluruh daerah. Kurkumin yang merupakan unsur utama kunyit, merupakan antioksidan yang kuat. Penelitian terdahulu melaporkan bahwa ekstrak etanolik Curcuma Zonga menyebabkan kematian sel sejumlah separuhnya pada sel HeLa setelah dipapar selama 24 jam dengan konsentrasi 184,5 lg/ml, tetapi tipe kematian sel dan mekanismenya belum jelas. Tujuan penelitian ini adalah untuk mengkaji pengaruh ekstrak Curcuma Zonga pada tipe kematian sel HeLa. Sel HeLa (5 x104 sel/well) dikultur dalam RPMI 1640 semalam sebelum stimulasi. Ekstrak etanol kunyit (150 lg/ml) ditambahkan pada kultur HeLa dan diinkubasi selama 24 jam dalam medium tanpa antibiotik. Analisis tipe kematian sel HeLa dilakukan dengan menggunakan mikroskop fuoresence setelah doubZe staining acridine orange/ethidium bromide (AO/EB). Doksorubisin (0,5625 Ig/ml) digunakan sebagai kontrol positif induksi apoptosis. Hasil penelitian menunjukkan bahwa ekstrak Curcuma Zongamenyebabkan kematian sel berupa apoptosis pada sebagian besar sel HeLa yang ditandai dengan perubahan warna sel menjadi orange. Analisa statistik menunjukkan perbedaan yang bermakna antara kelompok kontrol negatif dengan kelompok stimulasi dalam jumlah sel yang mengalami apoptosis. Disimpulkan bahwa ekstrak Curcuma Zonga mampu menginduksi apoptosis pada sebagian besar sel HeLa.
Kata kunci: ekstrak Curcuma Zonga, sel HeLa, apopt
PENYAKIT KAWASAKI
Authors: Indrarto FX.Wikan 
Published: August 2018

Penyakit Kawasaki adalah sebuah sindrom vaskulitis akut yang dominan mempengaruhi arteri kecil dan menengah, terutama mengenai anak balita. Gejala klinis penyakit Kawasaki sering dimulai dengan demam tinggi dan terus-menerus selama 2 minggu.
Penyakit Kawasaki hanya dapat didiagnosis secara klinis dan tidak ada pemeriksaan laboratorium yang khusus. Diagnosis klinis berdasarkan adanya demam 5 hari, ditambah 4 dari 5 kriteria diagnostik berikut ini: (1) eritema bibir atau rongga mulut atau retak bibir, (2) ruam kulit, (3) pembengkakan pada tangan atau kaki, (4) mata merah (injeksi konjungtiva), dan (5) pembesaran getah bening di leher minimal 15 milimeter.
Anak dengan penyakit Kawasaki mudah terjadi komplikasi aneurisma arteri koroner, terutama pasien yang tidak diobati secara dini dalam perjalanan penyakit. IVIG (imunoglobulin per infus) sebaiknya diberikan dalam dosis tinggi, yaitu 2 gr/ kgBB selama 10-12 jam. Terapi aspirin dimulai pada dosis tinggi 80-100 mg/kgBB/ hari dalam 4 dosis sampai 2-3 hari demam mereda, dan kemudian dilanjutkan dengan dosis rendah 3-5 mg/kgBB/hari, ketika pasien diijinkan pulang ke rumah.
Meskipun tidak diobati, sebenarnya gejala penyakit Kawasaki yang akut juga membaik, tetapi risiko terjadinya aneurisma arteri koroner jauh lebih besar. Tidak dikenal cara pencegahan untuk penyakit Kawasaki. Pencegahan dilakukan untuk menghindari perburukan kerusakan koroner.
Kata Kunci: kawasaki, diagnosis, treatment, prognosis
HIPNOTERAPI PADA PASIEN NYERI KRONIK
Authors: Nugraha Lucas Nando , Adisaputro Sugianto 
Published: August 2018

Nyeri adalah sensasi yang sangat menggangu dan mendorong pasien untuk berkunjung pada dokter. Bila nyeri yang diderita bersifat kronik maka akan menimbulkan penderitaan sangat berdampak pada kondisi sosial dan psikologis. Pada pengelolaan nyeri kronik diperlukan pendekatan multidisiplin dan holistik. Baik farmakologi maupun non-farmakologi, baik fisik maupun psikis.
Terapi non farmakologi yang akan dibahas pada tinjauan pustaka ini adalah hipnoterapi. Banyaknya teknik pada hipnoterapi sering membuat terapis sering kurang tepat dalam memilih teknik yang sesuai pada pengelolaan nyeri kronik sehingga menjadi tidak efektif dan efisien dalam proses terapi.
Hipnoterapi adalah terapi non-farmakologi yang tidak bersifat invansif dan dapat meminimalisir biaya dalam pengelolaan nyeri kronik. Hipnoterapi bersifat memandirikan pasien dengan adanya teknik anchoring sehingga dapat mengurangi morbiditas dalam kasus nyeri. Itulah sebabnya topik hipnoterapi ini diangkat dalam pembahasan ini.
Pada tinjauan pustaka ini menjelaskan teknik hipnoterapi yang sesuai sebagai terapi non-farmakologi dengan cara menimbulkan penerimaan terhadap rasa nyeri sehingga pasien mendapat manfaat pengobatan secara holistik dapat dalam pengelolaan nyeri kronik.
Círculo de estudos, observatório de educação e turismo de base comunitária: contribuições de metodologias participativas para o desenvolvimento local
Authors: Del Gobbo Giovanna , Nunes Eduardo José Fernandes , Morais Anaie Leite Silva 
Published: August 2018

Este trabalho discute metodologias participativas educacionais em dois países, Itália e Brasil, articuladas com as teorias sobre desenvolvimento local. Tanto o projeto do Círculo de Estudos (CE) na Itália quanto o Observatório de Educação de Jovens e Adultos do Território de Identidade do Sisal (OBEJA) e o Turismo de Base Comunitária (TBC no Cabula), na Bahia, Brasil, utilizam-se de metodologias que integram estratégias de intervenção social local, tendo como princípios o diálogo com a sustentabilidade, ação pública e a ação dos cidadãos. Na Itália, a Universidade de Florença, em parceria com o Centro de Educação Profissional na cidade de Gorizia, com financiamento da União Europeia, desenvolveu Círculos de Estudos com diferentes agentes sociais locais buscando estratégias de desenvolvimento local. No Brasil, na região do SISAL e na localidade do antigo quilombo Cabula Salvador, respectivamente o OBEJA e as intervenções do TBC em bairros populares, onde está inserida a Universidade do Estado da Bahia (UNEB), reacende perspectivas também para novos projetos de desenvolvimento local. Essas expreriências serão analisadas a partir de suas abordagens metodológicas e de suas ações para recuperar os conhecimentos e saberes de grupos sociais e a possibilidade de eles criarem seus próprios caminhos com autonomia e autogestão de seus ecossocioempreendimentos.
Development of tobacco plant cells in the presence of kanamycin at various levels for transgenesis Perkembangan sel tanaman tembakau pada kanamisin berbagai konsentrasi untuk transgenesis
Authors: SANTOSO D , CUGITO Ferry I , MINARSIH H 
Published: August 2018

Ringkasan Diferensiasi sel tanaman dalam proses regenerasi tanaman transgenik umumnya dilakukan bersamaan dengan proses seleksi menggunakan bahan penyeleksi. Kanamisin merupakan salah satu antibiotika yang biasa digunakan dalam proses seleksi. Dengan spektrum yang luas, kanamisin menghambat pertumbuhan sel dan mengganggu proses translasi pada saat ekspresi gen. Untuk tujuan regenerasi tanaman transgenik yang mengeks-presikan gen NPTII, konsentrasi kanamisin perlu dioptimasi sehingga cukup untuk membedakan sel yang tertransform dengan yang tidak tertransform. Penelitian ini betujuan untuk mempelajari perkembangan eksplan tembakau pada media regenerasi yang mengandung kanamisin. Kecepatan inisiasi tunas dan jumlah tunas terbentuk merupakan kriteria utama untuk evaluasi. Ekstrak protein dari eksplan yang berregenerasi dianalisa dengan SDS-PAGE untuk melihat kemungkinan keterlibatan protein tertentu dalam proses regenerasi tersebut. Hasil penelitian menunjukkan bahwa konsentrasi optimum kanamisin untuk tujuan tersebut adalah 50 mg/L, dimana tunas tembakau transgenik terinisiasi pada hari ke 25 kultur sedangkan eksplan non-transgenik hingga hari ke 56 kultur tidak mampu menginisiasi tunas. Data analisis protein menunjukkan adanya 3 protein dengan ukuran terdenaturasi relatif kecil, antara 14,5 hingga 21,5 kDa pada eksplan yang berregenerasi, namun tidak dijumpai pada ekstrak eksplan yang tidak berregenerasi. Ketiga protein ini kemungkinan terlibat dalam proses regenerasi. Summary Plant cell differentiation toward regeneration of transgenic plants is usually conducted simultaneously with selection process in the presence of selecting agent. Kanamycin is one of antibiotics widely used as selection agent. Having a wide spectrum activity, kanamycin hinders cell growth through inhibition of translation process during gene expression. To regenerate transgenic plant expressing NPTII gene, the level of kanamycin has to be optimized so that high enough to differentiate genetically transformed cells from those untransformed. This research is aimed to investigate in vitro development of tobacco cells toward plantlet regeneration on the media supplemented with kanamycin. The rate of shoot initiation and number of shoots formed are the major criteria evaluated. Protein extracts of the regenerated explants were analyzed with SDS-PAGE to examine possible involvement of specific proteins in the regeneration process. The experimental result suggested that optimum level of kanamycin for the purpose is 50 mg/L, by which transgenic tobacco shoots were initiated at 25-day culture whereas the untransformed explants did not initiated any shoots even though after 56-day culture. Preliminary data from the protein analysis indicated the presence of relatively small size denatured proteins, between 14.5 and 21.5 kDa, likely to involved in the regeneration process.