bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting Methods for Analyzing Data on Fatal Outcome Possibility in the Combination of Acute Coronary Syndrome and Atrial Fibrillation According to the Krasnodar Region Registry
Authors: Tatarintseva Z. G. , Kosmacheva E. D. , Kruchinova S. V. , Akinshina V. A. , Khalafyan A. A. 
Published: July 2019

With the development of atrial fibrillation (AF), patients with acute coronary syndrome (ACS) are characterized by a twofold increase in the 30-day mortality compared with patients with sinus rhythm. In this regard, there is great interest in developing models of risk stratification to identify adverse outcomes in these patients with a view to more careful monitoring of patients in this group.Material and methods. For the construction of predictive models, a statistical method was used for the classification trees and, the procedure for neural networks implemented in the STATISTICA package. For the construction of prognostic models, a sample was used, consisting of 201 patients with and without fatal outcome; condition of each patient was described by 42 quantitative and qualitative clinical indices. Each patient belonged to one of 3 groups according to the type of AF: new-onset AF in ACS patient, paroxysmal AF, documented in an anamnesis before the episode of ACS and the constant or persistent form of AF.Results. To determine predictors of models predicting the possible fatal outcome of a patient, the Spearman correlation coefficient was used. Examination of the correlations for each of the 3 groups separately allowed to reveal clinical indicators for each group – predictors of predictive models with predominantly moderate correlations to the categorical variable “lethal outcome”. After analyzing the prognostic ability of the developed models, a software module was created in the Microsoft Visual C # 2015 programming environment to determine lethal outcome possibility in patients with ACS in the presence of AF using classification trees and neural networks.Conclusion. It is shown that for patients with ACS in the presence of AF, it is possible to construct mathematically based prognostic models that can reliably predict the lethal outcome possibility in patients based on actual values of clinical indices. In this case, clinical indicators can be both quantitative and qualitative (categorical), breaking patients into certain categories. Similar applications, unlike risk scales, are mathematically justified and can form the basis of systems for supporting decision-making.
Medication Adherence: does Patient Participation in Randomized Clinical Trials Affect on it?
Authors: Vasyukova N. O. , Lukina Yu. V. , Kutishenko N. P. , Martsevich S. Yu. , Zvonareva O. I. 
Published: July 2019

The article focuses on the problem of low adherence to treatment among patients, in general, and provides data on the high adherence among patients in randomized controlled trials. Low adherence remains one of the most debated and difficult problems to solve nowadays. Poor medication adherence of the patient can significantly worsen the effectiveness of treatment and leads to increased health care costs. And although the factors that improve adherence are varied, and include the skills of the doctor, the patient’s personal characteristics, the external environment, an individual approach to each patient and etc., the absence of a “gold standard” for assessing adherence in clinical practice makes it difficult to predict and significantly improve it among patients. Nevertheless, the article discusses the existing doctor-patient interaction model, which strictly regulates the algorithms and technical means to achieve the best medication adherence. Randomized clinical trials (RCT) are the basis of evidence-based medicine, the results obtained in RCT form the basis of existing clinical guidelines. While participating in RCT patients can receive comprehensive information about the disease, the effectiveness of drug therapy, possible side effects of the therapy being conducted, the research objectives and prognosis from their attending physician; patients are trained to be disciplined and adhere to the recommendations of the doctor. The RCT, for a number of objective reasons, uses a variety of methods for assessing adherence and ways to improve it, which leads to higher patient adherence then among patients in general.
Genetic, Epigenetic and Transcription Factors in Atrial Fibrillation
Authors: Sapelnikov O. V. , Kulikov A. A. , Favorova O. O. , Matveeva N. A. , Cherkashin D. I. , Nikolaeva O. A. , Akchurin R. S. 
Published: July 2019

Atrial fibrillation (AF) is one of the most common arrhythmia that occurs in patients with cardiovascular diseases. Congenital forms of AF are quite rare. Many studies have shown that genetic, epigenetic and transcription factors may play an important role in the development and the progression of AF. In our review, studies have been conducted on the identification of mutations in ionic and non-ionic channels, possibly associated with AF. These mutations were found only in isolated groups of patients with AF, and in general, monogenic forms of AF are a rare subtype of the disease. Genomic association studies have helped to identify potential links between single nucleotide polymorphisms and AF. The risk of AF in the general population is likely to be determined by the interaction between environmental factors and many alleles. In recent years, the emergence of a genome-wide associative studies has significantly expanded the understanding of the genetic basis for the inheritance of AF and has led to the emergence of new evidence of the important role of genetic factors in the development of AF, in the risk stratification of AF and the recurrence of AF. Epigenetic factors are also important in AF. Epigenetic therapy aimed at treating a disease through exposure to epigenome is currently under development. A newly emerged area of ablatogenomics includes the use of genetic profiles that allow assessing the likelihood of recurrence of AF after catheter ablation. The results of genetic studies in AF show that, in addition to their role in the appearance of congenital heart pathologies, transcription factors play an important role in the pathogenesis of AF.
Hypertension and Headache: the Effect of Antihypertensive Drugs
Authors: Parfenov V. A. , Ostroumova T. M. , Ostroumova O. D. 
Published: July 2019

Headache is considered to be one of the main symptoms of arterial hypertension (HT). Complaints of headache are presented by many patients with HT: from 44% to 87%. It is obvious that the majority of complaints of headache in patients with HT is not due to headaches due to increased blood pressure (BP), but multimorbidity (polymorbidity) – the presence of coexisting primary headaches, most often, as in the population as a whole, chronic tension headache (57-85%) and migraine (15-30%). On the other hand, the frequency of HT in patients with migraine ranges from 32% to 44%. The relationship between migraine and HT may be due to common exogenous (external) and endogenous (genetic) factors, as well as common pathophysiological mechanisms. External risk factors, which can be associated with both migraine and HT, include the nature of the diet (excessive consumption of table salt with food), low physical activity, chronic stress; both diseases are also associated with the presence of a connection with the metabolic syndrome. The role of hyperactivation of the renin-angiotensin-aldosterone and adrenergic system and endothelial dysfunction are actively discussed. Angiotensin-converting enzyme takes an active part in the BP control and vascular tone; it is known that some angiotensin converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) have demonstrated efficacy in preventing migraine attacks. The presence of HT can contribute to the chronic course of primary headache, and effective treatment of HT with antihypertensive drugs, on the contrary, can have a positive effect on the course of primary headaches. Antihypertensive drugs reduce the frequency of headaches compared to placebo, but heterogeneity between different classes was revealed. There was a statistically significant decrease in the frequency of headaches compared to placebo during treatment with beta-blockers, ACEI, ARB, diuretics, while calcium antagonists did not reduce the frequency of headaches. According to a number of studies, the frequency of headaches during the treatment with ARB (candesartan) is comparable to that in the placebo group. Some antihypertensive drugs are used to prevent migraine attacks.
Mammographic Screening as a Tool for Cardiovascular Risk Assessing. Part 2. Association of Breast Arterial Calcification and Cardiovascular Diseases
Authors: Bochkareva E. V. , Kim I. V. , Butina E. K. , Stulin I. D. , Trukhanov S. A. , Rudenko B. A. , Boytsov S. A. , Drapkina O. M. 
Published: July 2019

Prospects for the use of mammographic detection of breast arterial calcification (BAC) to improve the stratification of cardiovascular risk in the female population are of increasing interest. The purpose of the 2 part of the review is the analysis of modern literature on the relationship of the BAC with the prevalence and mortality from cardiovascular diseases (CVD). The presence of BAC on mammograms is associated with a higher likelihood of myocardial infarction, death from coronary heart disease (CHD) and CVD, as well as a 3.5-fold increase in the risk of CHD and a 5-year coronary incident (p=0.003). Women with BAC have a higher likelihood of coronary artery disease detected during angiography than women without BAC (p<0.001). Severe BAC has a stronger association with CVD than mild calcification. The association of BAC with cerebrovascular diseases and a 1.4-fold increase in the risk of ischemic stroke (p=0.004), atheromatosis of the carotid arteries and an increase in the thickness of the intima-media complex is shown. BAC is associated with atherosclerotic lesions of peripheral arteries and a decrease in the ankle-brachial index <0.9 (p=0.048). In women with chronic kidney disease, the presence of BAC indicates a 4.5-fold increase in the risk of complications associated with impaired blood flow in peripheral arteries. It is shown that the addition of BAC to the generally accepted (standard) vascular risk assessment algorithms Framingham Risk Score and Pooled Cohort Equation significantly increases the accuracy of prediction of CHD (p=0.02 and p=0.010, respectively). The detection of BAC on mammographic screening is a new promising direction for cardiovascular prophylaxis in women and opens up new opportunities for identifying groups of people with subclinical forms of CVD and high cardiovascular risk.
Modern Concepts of Fibromuscular Dysplasia of the Coronary Arteries
Authors: Trisvetova E. L. 
Published: July 2019

Fibromuscular dysplasia of the coronary arteries is a rare non-atherosclerotic and non-inflammatory vascular lesion that is asymptomatic until serious complications develop: stenosis, dissection, rupture, sudden cardiac death. Since there are no long-term numerous clinical observations of patients with fibromuscular dysplasia of the coronary arteries, recommendations have not been developed for diagnosing and treating the disease, which often manifests with acute coronary syndrome. In 2014, the European Consensus was published, and in 2019, the first international consensus document on the diagnosis and treatment of fibromuscular dysplasia with lesions of vessels from different regions (renal, cerebrovascular, coronary, and others). The documents state that the development of fibromuscular dysplasia of the coronary arteries considers the participation of the PHACTR1 gene mutation and the transcriptional activity of the EDN1 gene, smoking, prolonged exertion of the vascular wall, and possibly female sex hormones. In the case of acute coronary syndrome, the most informative diagnostic method is computed tomography with angiography, which reveals a smooth narrowing of the lumen in the middle or distal section in the epicardial artery, often due to intramural hematoma, and also finds dissection, spasm, and tortuous vessel. Additional diagnostic methods ‒ intravascular ultrasound and optical coherence tomography allow differentiation of fibromuscular dysplasia with atherosclerosis of the coronary artery, vasculitis, and other diseases. The choice of treatment tactics for fibromuscular dysplasia of the coronary arteries depends on the severity of the clinical manifestations ‒ conservative medical treatment and interventional methods are used.
Psikopatologi dan Psikoterapi dalam Perspektif Tasawuf Ibn Qayyim Al-Jawziyyah
Authors: Maslahat Meta Malihatul 
Published: July 2019

<p class="06IsiAbstrak">This study aims to analyze the study of psychopathology and psychotherapy from the perspective of Sufism Ibn Qayyim al-Jawziyyah. This research belongs to the research library type research using qualitative methods. The theories used are the theory of mental illness and therapy belonging to Ibn Qayyim al-Jawziyyah in the book Ighātsah al-Lahfan min Mashāyid al-Syaithān. The results of this study indicate that according to Ibn Qayyim al-Jawziyyah, mental illness is defined as a disease caused by an imbalance between the dimensions of gifts and the inner dimensions that exist in humans. It is this imbalance of the gift and inner dimensions which is then simulated by psychopathology in a psychological perspective. People who experience this psychopathology must be treated immediately. The medicine to treat people who are mentally ill in psychological terms is called psychotherapy. According to Ibn Qayyim al-Jawziyyah medicine or psychotherapy that can help sufferers get out of psychiatric disorders namely by means of repentance, muhasabah, mujahadah and muraqabah and through prayer and understanding the values of Alquran. </p>
Religious Guidance and Counseling For Listeners of Dangdut Radio in Jakarta Indonesia
Authors: Arbi Armawati 
Published: July 2019

<p class="06IsiAbstrak">Religious counselors in current days seldom come forward in mass media, especially in radio. They prefer to introduce their selves as Islamic preacher. Furthermore, Islamic counselor is rarely as program director and producer in radio. This article offers what is very significant roles and functions of Islamic counselor (IC) on air program and off-air program in order families look for Islamic counseling. This research methods using observation, text analysis on record cassette, and script of fragment, deep interview on Fattahuddin as Islamic Counselor, and literature studies. Data were analyzed by constructivism paradigm. It was conducted by dialect among subjective reality, symbolic reality, and objective reality through externalization, objectivities, and internalization. The results of research reveal two findings: 1). Fatahuddin is religious guidance and counseling in <em>Daerah Khusus Ibukota (DKI) Jakarta,</em> religious affairs. He had used radio schema to construct family problems in Jakarta <em>Dangdut</em> radio through 6 stages.2). He had framed the concepts of <em>Sakinah</em> Family through format of Dialog Listeners and Broadcasters by using fragments 1 and 2, script of cases and solutions.</p>
Quo Vadis Ormas Islam Moderat Indonesia? Meneropong Peran NU-Muhammadiyah di Era Revolusi Industri 4.0
Authors: Fithriyyah Mustiqowati Ummul , Umam Muhammad Saiful 
Published: July 2019

<p><em>This paper aims to discuss the practice of Islamic moderation which has been carried out by the two largest Islamic mass organizations in Indonesia, namely the Nahdlatul Ulama (NU) and Muhammadiyyah primarily in the era of the Industrial Revolution (RI) 4.0. This article is written with the library research method. This study is descriptive explorative which analyzes the challenges of Nahdlatul Ulama and Muhammadiyyah in the aspects of da'wah and social in the fourth industrial revolution era. The conclusions of this study are: 1) NU and Muhammadiyah consistently guard the Indonesian nation with the value of Islamic moderation, without colliding between Islam and the Indonesian State; 2) Era (RI) 4.0 which is also known as the era of disruption requires NU and Muhammadiyyah to take part in utilizing technology to respond to the progress of the times in today's society. 3) In answering the challenges in this era of disruption, the two Islamic organizations need to make strategic efforts to counter Islamic radicalism, especially in the digital world;</em></p><p><em> </em></p><p><em>Key Words: Moderation, Islam, Nahdlatul Ulama, Muhammadiyyah, Industrial Revolution 4.0.</em></p><p><em> </em></p>
Dimensi - Dimensi Strategis Administrasi Publik dalam Islam
Authors: Pramesti Maya Wulan 
Published: July 2019

<p class="06IsiAbstrak"><strong><em>Strategic Dimensions of Public Administration in Islam</em></strong>.<strong> </strong>Public administration as the work of government to governance all resources in serving public to gain public welfare. Therefore there are some strategic dimensions concerning to the governance of public administration such as public policy, structure of organization, management, ethic, environment and performance. Those dimensions would not running and inter connected well, when the values are different and bad behaviour such as corruption, laziness, ego, still become apart of public administrators. The value of Islam as the believe to Allah, guide the human to life and work well, dependently or independently. Islam govern the society to runs Allah’s rules in their daily life. This paper through literature research tried to explaining how the values of Islam covering the strategic dimensions in public administration. As a moslem country, Indonesia needs to understand how’s the values of Islam and how to implement the values in their daily lives.</p><p class="07KatakunciKeywords"> Keywords: the values of islam, public administration, the work of government.</p>
Fenomena Politik Cebong dan Kampret di Indonesia: Sebuah Analisis dari Perspektif Pemikiran Politik dalam Islam
Authors: Hamid Abdulloh , Darwis Darwis , Andriyani Santi 
Published: July 2019

<p class="06IsiAbstrak"><span lang="EN-GB">Labelling <em>cebong</em> and <em>kampret</em> among supporters of Joko Widodo and Prabowo Subianto has been stronger in political phenomenon of Indonesia. This research aims to compare the political polarization after death of Prophet Muhammad with political polarization which is happening right now in Indonesia by using approach of Islamic political thought. This research also used library research as methodology of research to analyse the equal between bhoth phenomena in order to take lesson from the old phenomenon in mainting the unity of people in contemporary phenomenon exactly in Indonesia. The research found that to gain political power always cause polarization and conflict among people within society. Indonesian must learn from it to safeguard the unity of Indnesia as nation state</span></p><span> Keywords: Cebong, Kampret, Politic, Islamic Political Thought</span>
Kajian Kepribadian Presiden Perancis Emmanuel Macron Menggunakan Level Analisis Individu
Authors: Puspitarini Renny Candradewi , Afkarin Sofiatul 
Published: July 2019

<p class="06IsiAbstrak"><strong>Individual Level Analysis of France President Emmanuel Macron.</strong><strong> </strong>This paper is the result of an individual level analysis study conducted to explain qualitatively the personality, motivation and beliefs of French President Emmanuel Macron. This study employs qualitative data consisting of event data collected from various news sources with exclusionof exclusive interviews and state speeches and studied since Emmanuel Macron was inaugurated as President of France on May 17, 2017. Explanations regarding personality, motivation and beliefs assist to compile the rationality built on the record of educational background, family background, personality also helps to identify the relationship between leadership styles, motivation for decisions and actions that reflect the direction of French foreign policy. While beliefs are recognized through statements and answers given by for questions raised by journalists or foreign journalists in certain situations. This paper using a framework of individual analysis studies by Valerie Hudson, Jerrold Post and Margaret Hermann, it is concluded that Emmanuelle Macron is classified as a type of leader who is inconsistent with the characteristics of expansionist ambitions, high information complexity, good level of diplomatic knowledge or training and always had a consideration to invite other countries to establish harmonious and strategic relations with France.</p><p class="07KatakunciKeywords">Keywords: individual level analysis, leadership type, conciliatory leadership type, foreign policy analysis</p>
Drama of Avangers in Time Capsule as Practice of Politic-Cultural Representation (Cultural Appropriation or Cultural Appreciation?)
Authors: Mote Edoardo 
Published: July 2019

<p>At the inauguration of Time Capsule in Merauke, Mrs, Iriana have carried a Papuan child on her back while stepping on the place where all hopes and dream of Indonesia children kept until 2085 to be opened. She then obtained many compliment from people across the islands of Indonesia. People looked it as a form of empathy for Papuan’s problems.</p><p>Actually, what Mrs. Iriana did was political communication through practice of cultural representation. Her performation on that event was then framed as a cultural appreciation for Papuan culture and also become message for Papuan that she understand and have big empathy for Papuan problem. Yet, as we see in this Paper, I problematize the claim about this frame through theory of Eating the Other from Bellhook.</p><p>Eating the Other as negative model of dominative culture adopting sub-ordinate culture. By adopting element of sub-ordinate culture, the dominant can gain control to reproduce meaning of cultural codes and political representation at the politic stage. The control is by absorbing the sub-ordinate culture (assimilation) and removal subject of culture sub-ordinate in the public area. In this case, eating the other is operationalized through cultural appropriation as an oppositional form of cultural appreciation.</p><p>Cultural appropriation can be detected when someone who practice of cultural representation of other’s culture does bias of knowledge, values and socio-historical context where this culture come from. By this false practice of cultural representation, someone falls into an imaging merely without any substance. Even, it can be seen as humiliate for people who have that culture. In the other words, this is a bad practical of political representation at the politic stage and this is fatal for political communication as a whole.</p><p>My conclusion in this paper is what Mrs. Iriana did at the event is felt into cultural appropriation because it was only for merely imaging in front the people. The main reason is because her practice of cultural representation did not reflect her real act for relief the suffer of Papuan Mothers who live under poverty, less healthy service, double burden and another kind of violence that is faced in everyday of their life. This argument is affirmed by what Jokowi her husband as president have bad track record of human rights issue in Papua.</p><p> </p><p>Keyword : Eating the Other, Practice of Cultural Representation, Cultural Appropriation, Political Representation, Mrs. Iriana, Papuan Mothers</p>