bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative MRI-assisted neuro-port surgery for the resection of cerebral intraparenchymal cavernous malformation
Authors: Zhao Min , Lu Changyu , Liang Jianfeng , Zhao Yuanli , Chen Xiaolei 
Published: September 2019

Abstract

Background
Intraparenchymal cerebral cavernous malformation is difficult to localize intraoperatively with conventional frameless navigation due to the “brain shift” effect. We conducted this study to evaluate the efficacy and safety of intraoperative magnetic resonance image (iMRI)-assisted neuro-port surgery for the resection of cerebral intraparenchymal cavernous malformation.

Methods
Between April 2016 and December 2017, 54 consecutive patients with intraparenchymal cerebral cavernous malformation who get surgical treatment in our hospital were enrolled into this study. Twenty-one patients were treated using iMRI-assisted neuro-port surgery (experiment group), and 33 patients underwent treatment by conventional microsurgery (control group). The iMRI was used in all cases for the compensation of the “brain shift” effect and keeping the navigation system up-to-date. The surgical resection rate, the total operation time, and the preoperative and postoperative Karnofsky Performance Status (KPS) scores were determined to evaluate the operative procedures.

Results
There were no significant differences between the two groups in mean age, gender ratio, and volume of lesions (P > 0.05). For the experiment group, the average duration of the procedure was 188.8 min with total resection of the lesions achieved in all 21 cases. For the control group, the average duration of the procedure was 238.2 min with total resection of the lesions achieved in 25 of 33 cases. The differences in the average duration of the procedure and the number of totally resected lesions between the two groups were statistically significant (P < 0.05). Regarding postoperative neurological function, postoperative KPS scores for the experiment group were significantly higher than those of the control group (P = 0.018).

Conclusion
Our results show that iMRI-assisted neuro-port surgery is helpful for intraparenchymal cerebral cavernous malformation surgery. The method provides high accuracy and efficiency for lesion targeting and permits excellent anatomic orientation. With the assistance of iMRI technology, we achieved a higher resection rate and a lower incidence of postoperative neurological deficits. Additionally, iMRI is helpful for the compensation of the “brain shift” effect, and it can update the navigation system.
bicoid RNA localization requires the trans-Golgi network
Authors: Cai Xiaoli , Fahmy Khalid , Baumgartner Stefan 
Published: September 2019

AbstractBackgroundThe formation of thebicoid(bcd) mRNA gradient is a crucial step for Bcd protein gradient formation inDrosophila. In the past, a microtubule (MT)-based cortical network had been shown to be indispensable forbcdmRNA transport to the posterior.ResultsWe report the identification of a MT-binding protein CLASP/Chb as the first component associated with this cortical MT network. Since CLASPs in vertebrates were shown to serve as an acentriolar microtubule organization center (aMTOC) in concert withtrans-Golgi proteins, we examined the effect of theDrosophila trans-Golgins onbcdlocalization and gradient formation. Using a genetic approach, we demonstrate that theDrosophila trans-GolginsdGCC88,dGolgin97anddGCC185indeed affectbcdmRNA localization during oocyte development. Consequently, thebcdmRNA is already mislocalized before the egg is fertilized. The expression domains of genes downstream of the hierarchy ofbcd, e.g. of the gap geneempty spiraclesor of the pair-rule geneeven-skippedare changed, indicating an altered segmental anlagen, due to a faultybcdgradient. Thus, at the end of embryogenesis,trans-Golgin mutants showbcd-like cuticle phenotypes.ConclusionsOur data provides evidence that the Golgi as a cellular member of the secretory pathway exerts control onbcdlocalization which indicates thatbcdgradient formation is probably more intricate than previously presumed.
Trait emotional experience in individuals with schizophrenia and youth at clinical high risk for psychosis
Authors: Yee Claire I. , Strauss Gregory P. , Allen Daniel N. , Haase Claudia M. , Kimhy David , Mittal Vijay A. 
Published: September 2019

BackgroundDisturbances in trait emotions are a predominant feature in schizophrenia. However, less is known about (a) differences in trait emotion across phases of the illness such as the clinical high-risk (CHR) phase and (b) whether abnormalities in trait emotion that are associated with negative symptoms are driven by primary (i.e. idiopathic) or secondary (e.g. depression, anxiety) factors.AimsTo examine profiles of trait affective disturbance and their clinical correlates in individuals with schizophrenia and individuals at CHR for psychosis.MethodIn two studies (sample 1: 56 out-patients diagnosed with schizophrenia and 34 demographically matched individuals without schizophrenia (controls); sample 2: 50 individuals at CHR and 56 individuals not at CHR (controls)), participants completed self-report trait positive affect and negative affect questionnaires, clinical symptom interviews (positive, negative, disorganised, depression, anxiety) and community-based functional outcome measures.ResultsBoth clinical groups reported lower levels of positive affect (specific to joy among individuals with schizophrenia) and higher levels of negative affect compared with controls. For individuals with schizophrenia, links were found between positive affect and negative symptoms (which remained after controlling for secondary factors) and between negative affect and positive symptoms. For individuals at CHR, links were found between both affect dimensions and both types of symptom (which were largely accounted for by secondary factors).ConclusionsBoth clinical groups showed some evidence of reduced trait positive affect and elevated trait negative affect, suggesting that increasing trait positive affect and reducing trait negative affect is an important treatment goal across both populations. Clinical correlates of these emotional abnormalities were more integrally linked to clinical symptoms in individuals with schizophrenia and more closely linked to secondary influences such as depression and anxiety in individuals at CHR.Declaration of interestNone.
When is early return too early? Clavicle plate fixation in Australian Rules football athletes: A retrospective review of cases
Authors: Ricks Matthew , Borbas Paul , Perret Michael , Warby Sarah , Hoy Greg 
Published: September 2019

Background: We retrospectively reviewed return to sport times and results for a series of professional Australian Rules football (AFL) players after clavicle fracture management using a precurved Titanium (Acumed) plate and screws. We allowed very early use and aimed to assess if this construct is strong enough to withstand collision sport activities before radiological union is confirmed. Methods: We reviewed 14 consecutive senior listed AFL players who underwent plate fixation by the senior author over a 10 year period. Outcome measures were taken between 12 and 36 months post operatively and included time to return to play, Nottingham Clavicle Score (NCS) and the Oxford Shoulder Score. Results: The median time for return to training was 3.5 weeks and 6 weeks for return to full competition. All fractures eventually united. Three of the players that returned before 6 weeks post-operatively suffered significant impacts that caused a bend in the titanium plates. One of these required revision fixation surgically due to perceived weakness in the bent plate construct and cosmetic deformity. The mean Nottingham Clavicle Score and Oxford Shoulder Score were 87.9 and 45.1 points respectively. Survival analysis showed that more than half of the players returned to training at 4 weeks and over 80% at 12 weeks. Discussion: The decision to operate early on AFL players who suffered a clavicle fracture in competition play resulted in excellent longterm results. However, the decision to return some players earlier than accepted times for bony union resulted in bending of plates in a significant number, and the risk of further injury must be weighed up in a collision sport. The early return to play time had no adverse effects on performance and participant satisfaction was high, as reflected by the Nottingham Clavicle score and the Oxford shoulder score.
Suunta ja muutos. Havantoja suomen ja viron liikeverbeistä
Authors: Tommola Hannu 
Published: September 2019

Käesolevas artiklis püütakse selgitada eesti ja soome keele kõige sagedasemate liikumisverbide polüfunktsionaalsust.Soome keele tulla vastab küll põhitähenduses eesti verbile tulema, kuid ei väljenda lahkumist –seda väljendatakse soome keeles verbiga lähteä. Samuti erinevad meie keeled inhoatiivi väljendamises: soome keele kõige tavalisem muutumisverb on tulla, eesti keeles aga saama. Soome keele verbi jäädä ja eesti keele verbi jääma on vaadeldud liikumisverbidena nende võimaliku muutuse presupositsiooni tõttu. Jääma väljendab siiski ka seisundi tekkimise tähendust. See tähendus esineb soome verbil jääda vaid idioomides. Eesti keele jääma on näide polüseemia tüübist, mida on nimetatud enantioseemiaks (ühel ja samal lekseemil on vastandtähendused).Üks läänemeresoome liikumisverbide omapära näiteid on verb käydä/käima, mis võimaldab väljendada kahesuunalist liikumist. Soome ja eesti verbide põhitähendused on sarnased, aga kõigis kasutustes käydä ja käima ei kattu, sest käydä esineb ka muutumisverbina, eesti verbil see tähendus puudub. Lõpuks käsitletakse lühidalt idiomaatilisi väljendeid, nt. tulikuntoon / menipieleen ning läks korda/viltu
Evaluative language in spoken and signed stories told by a deaf child with a cochlear implant: words, signs or paralinguistic expressions?
Authors: Nieminen Lea , Takkinen Ritva 
Published: September 2019

In this paper the use and quality of the evaluative language produced by a bilingual child in a story-telling situation is analysed. The subject, an 11-year-old Finnish boy, Jimmy, is bilingual in Finnish sign language (FinSL) and spoken Finnish. He was born deaf but got a cochlear implant at the age of five. The data consist of a spoken and a signed version of “The Frog Story”. The analysis shows that evaluative devices and expressions differ in the spoken and signed stories told by the child. In his Finnish story he uses mostly lexical devices – comments on a character and the character’s actions as well as quoted speech occasionally combined with prosodic features. In his FinSL story he uses both lexical and paralinguistic devices in a balanced way
A Comparison of Health Disparities Among Americans With Intellectual Disability and/or Autism Spectrum Disorder and Americans With Other Disabilities
Authors: Hall Jean P. , Kurth Noelle K. 
Published: September 2019

Abstract
This article uses recent survey data to compare and contrast American adults with intellectual disability (ID) and/or autism spectrum disorder (ASD) and those with other disabilities with regard to overall health, access to health care, and other aspects of community participation. Although people with ID and/or ASD and others with disabilities share many issues related to poorer health and access to care compared to the general population, adults with ID and/or ASD reported different experiences and outcomes than other people with disabilities. An examination of these differences provides insights into policy changes and targeted interventions that might improve overall health and community inclusion specifically for people with ID and/or ASD.
InGaAs APD matrix sensors for SWIR gated viewing
Authors: Rutz Frank , Aidam Rolf , Heußen Henning , Bronner Wolfgang , Rehm Robert , Benecke Matthias , Sieck Alexander , Brunner Simon , Göhler Benjamin , Lutzmann Peter 
Published: September 2019

Abstract
Short-wavelength infrared (SWIR) detection systems are increasingly in demand for surveillance, reconnaissance, and remote sensing applications. Eye-safe SWIR lasers can be utilized for active imaging systems with high image contrast and long detection range. The gated-viewing (GV) technique using short-pulse lasers and fast-gated cameras in the nanosecond range enables utilizing the distance information in addition to the signal intensity of the acquired images. The InGaAs material system is very well suited for the fabrication of high-performance SWIR photodetectors providing a typical cutoff wavelength of 1.7 μm, which covers the emission lines of available laser sources at typical telecom wavelengths around 1.55 μm. However, the usually short integration times needed for GV leads to very small photosignals. We report on the development of SWIR avalanche photodetector (APD) arrays with 640 × 512 pixels and 15 μm pixel pitch based on the InGaAs material system. The InGaAs-APD focal plane arrays have been successfully integrated into SWIR cameras which yield gain values of M ≈ 10 on camera level at a reverse bias voltage around 21 V and are the first InGaAs-based SWIR cameras worldwide providing a 640 × 512 image format and utilizing avalanche gain for signal amplification. The camera performance is demonstrated by SWIR laser GV sample images.
Ophioglossaceae (Psilotopsida) in Ukraine
Authors: Parnikoza Ivan , Chernyshenko Maria , Celka Zbigniew 
Published: September 2019

Abstract
The paper considers current ranges, population dynamics, habitats, threats and conservation measures of Ophioglossaceae of the Ukrainian flora. Only one specimen of Botrychium simplex was discovered in herbarium at the begining of the 19th century. Taxonomical status of Ophioglossum azoricum in Ukraine needs additional studies. Other species of the family remain rare in Ukraine; there are only two reliable current localities of B. virginianum, and seven of B. matricariifolium. The number of B. multifidum, B. lunaria and Ophioglossum vulgatum localities have been decreasing since 1980 in comparison with the previous period, especially in the lowland part of the country. This tendency is accompanied by a very low stability of well-known populations – only some of them have been occurring from before 1980 up to modern times. Current conservation of Ophioglossaceae species in the protected areas is insufficient; it is necessary to create some new and enlarge some of the existing nature protection areas and include Botrychium simplex and Ophioglossum vulgatum in the Red Data Book of Ukraine.
Risk Tolerance, Legitimacy, and Perspective: Navigating Biases in Social Enterprise Evaluations
Authors: Murphy Patrick J. , Pollack Jeff , Nagy Brian , Rutherford Matthew , Coombes Susan 
Published: September 2019

AbstractSocial enterprises viewed as viable from societal perspectives are often regarded differently from traditional business perspectives. To examine this difference, we undertook two empirical studies of risk tolerance and legitimacy perceptions among observers of social enterprise and for-profit ventures. In Study 1, participants (n= 115) drawn randomly from Amazon’s Mechanical Turk, an online crowdsourcing marketplace for human intelligence tasks, examined two hypothetical cases and completed the risk tolerance scale of theJackson Personality Inventory. Results show that social enterprises were seen as having lower industry legitimacy, especially by individuals with lower risk tolerance. Here, industry legitimacy mediated the effect of venture purpose on cognitive legitimacy. In Study 2, practicing entrepreneurs (n= 23) narratively interpreted Study 1 results from social enterprise and traditional business perspectives. Both studies demonstrate that social enterprise legitimacy evaluations vary based on risk tolerance and the type of legitimacy in question. Overall findings show that explicit observations of risk tolerance effects, and multidimensional conceptualizations of legitimacy, are important to accurate evaluations of social enterprises.
Prescribing pattern of antihypertensive medication and adherence to Joint National Commission-8 guidelines in a rural tertiary care Indian teaching hospital
Authors: Venkataraman Rajesh , Rashid Muhammed , Shashikantha Bhat , Soumya Ayyappankalathil , Vijayan Greeshma , Manuel Gloriya Grifth , Islam Shahinur 
Published: September 2019

Abstract

Background
Antihypertensive medications are one among the most highly used drugs across the globe as well as in India, and their prescribing pattern will be erratic despite the various clinical guidelines. Few studies address the pattern and adherence to the standard treatment guidelines in India. This study aimed to review the prescribing pattern of antihypertensive medications in a rural tertiary care teaching Indian hospital and to investigate the adherence to the Joint National Commission-8 (JNC-8) guidelines on prevention, detection, evaluation, and treatment of hypertension in adults.

Methods
A prospective observational study was conducted among the participants from four different inpatient wards who are aged >18 years, without gender restriction. The prescription pattern was reviewed and adherence to the JNC-8 guidelines was also assessed. A purposive sampling technique was adopted and descriptive statistics were used in Statistical Package for the Social Sciences v16.

Results
Of the 101 participants included in the study, 62 (61.39%) were female, 23.76% were aged <30 and >60 years, and the other 52.48% belong to the range of 30–60 years. As per JNC-8 guidelines, 4.95%, 17.82%, 44.55%, and 32.67% of patients were classified as normal, pre-hypertensive, stage I, and stage II, respectively. Most of them (31.68%) were free from comorbidities. The most (23.76%) prescribed drug was calcium channel blocker (CCB), and 15.84% of the patients received combination therapy. Treatment was effective in 70.30% of the patients through analyzing their blood pressure even though the adherence to the JNC-8 guidelines was only in 54.46%.

Conclusions
Our study revealed that CCB was the most prescribed drug, and in spite of the only 50% adherence rate, treatment was effective in the majority of the population. The treatment outcome can be improved if the adherence rate is increased further.
Application of Selected Methods and Approaches for Improvement of Processes and their Use in Practice in Companies of Wood Processing Industry in Slovakia
Authors: Simanová Ľubica , Gejdoš Pavol 
Published: September 2019

Abstract
The aim of the paper is to point out the principles of process management and selected quality management tools, which are aimed at improving the processes of the wood processing industries of the Slovak Republic. The knowledge from these areas is based on the analysis of the theoretical origins from domestic and foreign sources and supported by the results of the research carried out in the first half of the year 2017. In the processing of the results, classical methods of research work were used such as analysis, synthesis, comparison, descriptive statistics, contingency tables, chi-quadrat test and graphic depiction. Based on the analysis of the research results, there was a slight dependence between the process optimization levels in the timber industry and other process improvement methods such as statistical process control methods and graphical analysis and problem solving tools.
Competitive Strategies in Higher Education: Scale Development
Authors: Ekeagbara Jane A. , Ogunnaike Olaleke Oluseye , Ibidunni Ayodotun Stephen , Kehinde Busola Elizabeth 
Published: September 2019

Abstract
Leveraging on resource based-view theory, this paper shows strategies adopted in higher education to remain competitive. Using scale development method, 60 questionnaires as survey instrument was distributed and 58 respondents completed and returned. The result of socio-economic demographic variables, factor analysis and validity using the statistical packages for social science. Five dimensions were adopted: cost leadership strategy, service differentiation strategy, cost focus strategy, integration strategy and diversification strategy. The validity and reliability result as well as managerial implication, limitation and future research were discussed.
An extended technology acceptance model for marketing strategies in social media
Authors: Nistor George Cristian 
Published: September 2019

Abstract
Social media is currently an evolving “wave” in online business marketing. Marketers are beginning to drive the use of social media as a component in their marketing strategy and campaigns to reach out to customers and fans. Within the subdisciplines of marketing that may use social media include promotions, marketing intelligence, sentiments research, public relations, marketing communications and product and customer management. This paper will try to find a conceptual model to examine people’s behavior, model based on the the Theory of Reason Action (TRA) and the Technology Acceptance Model (TAM).
Serum uromodulin is inversely associated with the metabolic syndrome in the KORA F4 study
Authors: Then Cornelia , Then Holger , Lechner Andreas , Huth Cornelia , Meisinger Christa , Heier Margit , Peters Annette , Koenig Wolfgang , Rathmann Wolfgang , Herder Christian , Roden Michael , Scherberich Jürgen , Seissler Jochen 
Published: September 2019

Objective
Metabolic syndrome and obesity are risk factors for chronic kidney disease. However, early kidney alterations may escape diagnosis in these conditions due to glomerular hyperfiltration. Uromodulin, a glycoprotein exclusively synthesized in tubular cells of the thick ascending limb of Henle's loop, is a novel tissue-specific biomarker for kidney function. In contrast to the commonly used markers creatinine and cystatin C, serum uromodulin does not primarily depend on glomerular filtration. We hypothesized that serum uromodulin is a marker for metabolic syndrome and related components.

Design
The analyses included 1088 participants of the population-based KORA F4 study aged 62–81 years. Metabolic syndrome was present in 554 participants. After a mean follow-up time of 6.5 years, 621 participants were reevaluated, of which 92 had developed incident metabolic syndrome.

Methods
The association of serum uromodulin with metabolic syndrome and its components were assessed using multivariable logistic regression models.

Results
Serum uromodulin was inversely associated with metabolic syndrome after adjustment for sex, age, estimated glomerular filtration rate, physical activity, smoking, alcohol consumption and high-sensitivity C-reactive protein (OR 0.65; 95% CI 0.56–0.76 per standard deviation uromodulin; P < 0.001). Serum uromodulin was inversely associated with all single components of metabolic syndrome. However, serum uromodulin was not associated with new-onset metabolic syndrome after the follow-up period of 6.5 ± 0.3 years (OR 1.18; 95% CI 0.86–1.60).

Conclusions
Serum uromodulin is independently associated with prevalent, but not with incident metabolic syndrome. Low serum uromodulin may indicate a decreased renal reserve in the metabolic syndrome.