bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antineutrophil Cytoplasmic Antibody–Associated Lung Fibrosis
Authors: Borie Raphael , Crestani Bruno 
Published: November 2018

AbstractPulmonary fibrosis is observed in a substantial number of patients with ANCA-associated vasculitis (AAV), 15% in a recent German series, and may be more frequent in Asian populations. ANCA are usually of anti-MPO specificity and microscopic polyangiitis is the most frequent vasculitis. Pulmonary fibrosis may increase the risk of death in patients with AAV. Treatment for AAV in patients with lung fibrosis should follow the international guidelines for vasculitis. The role of anti-fibrotic drugs (pirfenidone, nintedanib) in this condition is still unknown. Pulmonary fibrosis precedes the diagnosis of AAV or is diagnosed concomitantly in most of the cases. Interestingly, 4% to 35% of patients with pulmonary fibrosis are ANCA-positive, but only 7% to 23% of the patients with pulmonary fibrosis and anti-MPO will develop AAV during follow-up. ANCA positivity may be detected in idiopathic or non idiopathic pulmonary fibrosis. In the absence of vasculitis, the detection of ANCA does not influence the diagnostic work-up of patients with lung fibrosis. If an Idiopathic Pulmonary Fibrosis diagnosis is considered, an anti-fibrotic therapy should be considered, according to local and international guidelines.
A MSK Radiologist's Early Experience as a Department Chair: Climbing the Horizontal Ladder
Authors: Casagranda Bethany 
Published: November 2018

A radiologist's training is designed to produce a professional with excellent interpretation skills. However, in today's health care environment, a successful radiologist may not be a successful leader or the opposite may be true. Leadership requires a different set of skills with knowledge of common concepts across all levels of health care delivery. When asked to take on administrative responsibilities, you anticipate constant work with occasional glory, but you may not realize the ladder of success is actually horizontal and the spotlight quite bright.In this personal narrative, I have illustrated my pathway to the chair position in the context of climbing the career ladder and entering the stage of leadership. I discuss common concerns facing radiology today and how we can all use our experience and leadership skills to overcome these challenges with effective solutions.
Musculoskeletal Radiology Practice Subspecialization in Canada: A Subject of Substance?
Authors: Hiemstra Laurie , Forster Bruce , Walker Richard 
Published: November 2018

AbstractScientific and technological advances in medical imaging have had a profound impact on health care around the world including Canada. The cost of imaging, however, continues to rise along with innovation. Building a practical subspecialty musculoskeletal imaging service offers the specialty of radiology an opportunity to show how radiologists can consistently add value and improve outcomes without adding a great cost burden to the health care system.
Unusual Type of Hand Preaxial Polydactyly
Authors: Sirasanagandla Srinivasa , Nayak Satheesha , Al Mushaiqri Mohamed 
Published: November 2018

AbstractPreaxial polydactyly is a common congenital anomaly of the hand. In this anomaly, an additional digit is seen along the preaxial border of the thumb. Several possible types of preaxial polydactyly have been observed and categorized into several types based on the level of duplications. In the present case, we report an unusual type of polydactyly in an approximately 55year-old male cadaver of South Indian origin. An additional non-functional digit was noted along the preaxial border of the thumb, at the level of the base of the distal phalanx. Upon careful dissection of the anomalous digit, a thick cord of connective tissue formed by the fibrous flexor sheath around the flexor pollicis longus tendon was noted in its central core. This cord was surrounded by a mass of fatty tissue. The skeletal, muscle and tendon components were found to be absent in the additional digit.
Child with Susceptibility to Infection-Induced Acute Encephalopathy 3
Authors: Khalil Ayman , Malalla Husain Ali Ahmed , Naser Husain , Almuslamani Ahood 
Published: November 2018

AbstractA 10-month-old Bahraini boy born full-term to first-degree cousins, initially had normal developmental milestones, but presented with recurrent encephalopathy and seizures associated with upper respiratory tract infection. With each attack, the patient developmentally regressed further. Brain magnetic resonance imaging showed multiple old and new infarcts. Cerebrospinal fluid biochemistry, microbiology, and amino acids were unremarkable. Tandems mass spectrometry of urine organic acids was unremarkable as well. Electroencephalogram showed asymmetry with cortical irritability. Whole exome sequencing revealed a homozygous mutation of RAN-binding protein 2 gene, suggesting a diagnosis of susceptibility to infection-induced acute encephalopathy 3, which is an autosomal dominant condition. This is the first case to be reported in Bahrain.
Potential Use of Calcined Kaolinite-Based Wastes as Cement Replacements in Concrete – An Overview
Authors: Liu Yuxuan , Ling Tung-Chai 
Published: November 2018

Abstract
The use of supplementary cementitious material (SCM) to partially replace cement is a promising strategy to reduce CO2 emission and improve the overall sustainability of construction industry. Recent studies revealed that calcined clay could be used as a pozzolanic material and demonstrated an improvement in durability properties of concrete. The pozzolanic reactivity of calcined clay mainly depends on the kaolinite content due to its disordered crystal structure. They can use to replace cement at considerably high level (∼30%), and even higher (∼50%) if addition limestone powder is used. Since kaolinite is the key source of pozzolanic activity, reusing kaolinite-based waste materials could be a promising and sustainable approach instead of exploiting natural clay for calcined clay cement. This paper summarises recent published works on the use of calcined kaolinite waste as partial cement substitutions in concrete, including thermally activated coal gangue and pre-calcined clay brick and ceramic wastes which have been burnt in their fabrication process. The properties of concrete using these kaolinite-based waste materials are also discussed.
RNA profile diversity across arthropoda: guidelines, methodological artifacts, and expected outcomes
Authors: DeLeo Danielle M , Pérez-Moreno Jorge L , Vázquez-Miranda Hernán , Bracken-Grissom Heather D 
Published: November 2018

AbstractHigh-quality RNA is an important precursor for high-throughput RNA sequencing (RNAseq) and subsequent analyses. However, the primary metric used to assess RNA quality, the RNA Integrity Number (RIN), was developed based on model bacterial and vertebrate organisms. Though the phenomenon is not widely recognized, invertebrate 28S ribosomal RNA (rRNA) is highly prone to a form of denaturation known as gap deletion, in which the subunit collapses into two smaller fragments. In many nonmodel invertebrates, this collapse of the 28S subunit appears as a single band similar in size to the 18S rRNA subunit. This phenomenon is hypothesized to be commonplace among arthropods and is often misinterpreted as a “degraded” rRNA profile. The limited characterization of gap deletion in arthropods, a highly diverse group, as well as other nonmodel invertebrates, often biases RNA quality assessments. To test whether the collapse of 28S is a general pattern or a methodological artifact, we sampled more than half of the major lineages within Arthropoda. We found that the 28S collapse is present in ∼90% of the species sampled. Nevertheless, RNA profiles exhibit considerable diversity with a range of banding patterns. High-throughput RNAseq and subsequent assembly of high-quality transcriptomes from select arthropod species exhibiting collapsed 28S subunits further illustrates the limitations of current RIN proxies in accurately characterizing RNA quality in nonmodel organisms. Furthermore, we show that this form of 28S denaturation, which is often mistaken for true “degradation,” can occur at relatively low temperatures.
Cell-Type-Specific D1 Dopamine Receptor Modulation of Projection Neurons and Interneurons in the Prefrontal Cortex
Authors: Anastasiades Paul G , Boada Christina , Carter Adam G 
Published: November 2018

Abstract
Dopamine modulation in the prefrontal cortex (PFC) mediates diverse effects on neuronal physiology and function, but the expression of dopamine receptors at subpopulations of projection neurons and interneurons remains unresolved. Here, we examine D1 receptor expression and modulation at specific cell types and layers in the mouse prelimbic PFC. We first show that D1 receptors are enriched in pyramidal cells in both layers 5 and 6, and that these cells project to intratelencephalic targets including contralateral cortex, striatum, and claustrum rather than to extratelencephalic structures. We then find that D1 receptors are also present in interneurons and enriched in superficial layer VIP-positive (VIP+) interneurons that coexpresses calretinin but absent from parvalbumin-positive (PV+) and somatostatin-positive (SOM+) interneurons. Finally, we determine that D1 receptors strongly and selectively enhance action potential firing in only a subset of these corticocortical neurons and VIP+ interneurons. Our findings define several novel subpopulations of D1+ neurons, highlighting how modulation via D1 receptors can influence both excitatory and disinhibitory microcircuits in the PFC.
Chow Motives Without Projectivity, II
Authors: Wildeshaus Jörg 
Published: November 2018

AbstractThe purpose of this article is to provide a simplified construction of the intermediate extension of a Chow motive, provided that a condition on absence of weights in the boundary is satisfied. We give a criterion, which guarantees the validity of the condition, and compare our new construction to the theory of the interior motive established earlier. We finish the article with a review of the known applications to the boundary of Shimura varieties.
Societal Costs of Child and Adolescent Mental Health Disorders
Authors: Lynch Frances L. , Dickerson John F. 
Published: November 2018

Abstract
Costs related to mental health and neurodevelopmental conditions (MHNCs) in childhood are experienced by multiple groups, including families, public and private service systems, and society as a whole. This chapter provides a conceptual model of MHNC-related costs, reviews estimates of short-term and long-term costs, and discusses the role of economic evaluation of services. Our conceptual model suggests that it is critical to consider costs from a broad point of view, but current literature on cost of MHNCs is uneven, with significant focus on short-term health system costs and very little emphasis on long-term costs or costs outside the health system, such as costs to families. There is a growing body of literature on MHNC costs, but more emphasis is needed in areas where there is little data to ensure that decision-makers have comprehensive data on the impact of MHNCs in order to manage scarce resources equitably and efficiently.
Substance-Related and Addictive Disorders
Authors: Horan Fisher Jacqueline , Becker Sara , Bobek Molly , Hogue Aaron 
Published: November 2018

Abstract
Significant developmental changes in adolescence typically lead to increased risky behavior, including substance use. Survey data indicated that adolescent alcohol and drug use has declined in recent years, with the exception of marijuana use, which has remained consistent, and e-cigarette use, which is on the rise. This chapter provides a summary of prevalence rates, trends, and maladaptive consequences of adolescent substance use. Etiological models of adolescent substance use are discussed, including dual-process and biopsychosocial models. Current literature on evidence-based screening, comprehensive assessment, and treatment is also reviewed. Despite the recent advances made regarding our ability to screen, assess, diagnose, and treat adolescent substance use, a significant treatment gap persists, which has significant individual and public health impacts. This chapter therefore concludes with a call for research that aims to increase patient awareness of effective treatment via strategies such as technology-delivered assessment and intervention and usage of direct-to-consumer marketing.
Children of Divorce and Relationship Dissolution
Authors: Azar Sandra T. , Goslin Megan C. , Patallo Brandon J. 
Published: November 2018

Abstract
This chapter reviews outcomes in children where parental separation has occurred and their complex determinants. As the title suggests, many children encounter parental relationship ruptures that do not involve legal marriage, although our body of research has narrowly focused on this category. This chapter overviews methods used for conducting evaluations with special attention to the more nuanced approach needed when the evaluation occurs in the context of legal actions where custody is being decided. Finally, it highlights intervention strategies that have been used to reduce risk to children and families as they make these transitions. Attention is paid to both psychological interventions and more macrolevel changes aimed to buffer economic costs. Throughout the chapter, data are presented on diversity issues. The lack of findings for fathers in each topic and on dissolution when racial minorities or same-sex couples are considered is highlighted.
Children With Incarcerated Parents
Authors: Poehlmann-Tynan Julie , Runion Hilary , Weymouth Lindsay A. , Burnson Cynthia 
Published: November 2018

Abstract
More than 5 million US children have experienced a co-resident parent leaving for jail or prison. When parents are arrested, jailed, or sentenced to incarceration in jail or prison and released back into the community, their children experience changes at multiple levels. Children with incarcerated parents are more likely than their peers to experience multiple risk factors and stress exposures, including chronic poverty, parental unemployment, domestic violence, neighborhood violence, homelessness, and parental mental illness and substance abuse. Some risks occur prior to incarceration, whereas others occur during or following incarceration. This chapter provides a statistical portrait of children with incarcerated parents; reviews of risks commonly experienced by these children and research findings focusing on the well-being of children with incarcerated parents; a summary of incarceration-related experiences commonly encountered by affected children; and a discussion of implications for policy and practice.
Nonsuicidal Self-Injury Among Youth
Authors: Bryant Miller Adam , Massing-Schaffer Maya , Owens Sarah , Prinstein Mitchell J. 
Published: November 2018

Abstract
Nonsuicidal self-injury (NSSI) is direct, intentional harm to one’s own body performed without the intent to die. NSSI has a marked developmental onset reaching peak prevalence in adolescence. NSSI is present in the context of multiple psychological disorders and stands alone as a separate phenomenon. Research has accumulated over the past several decades regarding the course of NSSI. While great advances have been made, there remains a distinct need for basic and applied research in the area of NSSI. This chapter reviews prevalence rates, correlates and risk factors, and leading theories of NSSI. Further, it reviews assessment techniques and provides recommendations. Then, it presents the latest evidence-based treatment recommendations and provides a case example. Finally, cutting edge research and the next frontier of research in this area are outlined.
Pediatric Psychopharmacology: Commonly Used Medications in Children
Authors: Scahill Lawrence , Rojas Jaimie 
Published: November 2018

Abstract
Pediatric psychopharmacology is a relatively young field. Through the decade of the 1990s and into the early 2000s, there was an unprecedented increase in the number of new psychotropic drugs and new formulations of older drugs. During this period, there was also a series of well-intended federal policies that provided pressure and incentives for pharmaceutical companies to conduct studies of new medications in children. The National Institutes of Health also provided funding for investigator-initiated clinical trials. Although still less than optimal, we now have a body of data on stimulants, selective serotonin reuptake inhibitors, and atypical antipsychotics. These three psychotropic drug classes are the most commonly used in children and adolescents. This chapter charts the rise in use of these drug classes and presents their risks and benefits.
Psychiatric Epidemiology: Concepts and Findings
Authors: Reis Merikangas Kathleen , Hommer Rebecca 
Published: November 2018

Abstract
This chapter provides background on the discipline of epidemiology and its contribution to our understanding of childhood mental disorders. A summary is provided of data on the prevalence and correlates of mental disorders in children and adolescents in community surveys. Anxiety disorders are the most frequent conditions in children, followed by behavior disorders, mood disorders, and substance use disorders. About half of youth with one disorder also meet criteria for a second disorder, demonstrating the pervasive nature of comorbidity even in childhood. Less than half of youth with current mental disorders receive mental health specialty treatment. However, those with the most severe disorders tend to receive mental health services. Current issues that are now being identified in the field of child psychiatric epidemiology includes refinement of classification and assessment; integration of child and adult psychiatric epidemiology; and evaluation of both mental and medical disorders in children.
Communication Disorders: Neurodevelopmental Considerations
Authors: Dockrell Julie , Joye Nelly 
Published: November 2018

Abstract
Communication disorders are a common neurodevelopmental disorder. Difficulties are evident with structural language, phonology, and pragmatics. Each area is differentiated within current diagnostic approaches. However, difficulties within the language system often co-occur. The assessment of communication difficulties requires professionals to profile linguistic skills rather than rely on single diagnostic measures. Social communication disorders raise particular challenges in their assessment and their differentiation with other neurodevelopmental disorders. Communication disorders also co-occur, with problems in literacy and behavior highlighting the importance of multiprofessional approaches to assessment and intervention. There is an increasing evidence base for effective interventions that professionals can access to support children’s communication difficulties.
Assessment and Case Conceptualization
Authors: McLeod Bryce D. , Cox Julia R. , Martinez Ruben G. , Christon Lillian M. 
Published: November 2018

Abstract
Evidence-based assessment and case conceptualization are two important components of evidence-based practice. Using assessment data gathered over the course of treatment to inform case conceptualization helps clinicians tailor evidence-based treatments to meet the needs of individual children and adolescents. The main goal of this chapter is to describe and illustrate the roles evidence-based assessment and case conceptualization play in informing the process of psychosocial treatment for children and adolescents from the initial intake through termination. a framework guided by six principles for using assessment to inform the treatment process is presented. Then, how this framework can be used to develop and refine a science-informed case conceptualization through a series of five sequential stages is discussed. This process is illustrated with a case example. The chapter concludes with future research directions for assessment and case conceptualization to better inform evidence-based practice.
Dance-Off, or a Battle for the Future
Authors: Chakravorty Pallabi 
Published: November 2018

AbstractThe chapter examines the myriad meanings of dance competitions through the lens of Indian dance reality shows. It discusses reality shows such as Boogie Woogie, Dance India Dance, Naach Dhum Machale, and the production of new hybrid dances and remixes. The symbiotic relationship between Bollywood dance, reality shows, and the television industry creates the new aspirational aesthetics of “remix.” By combining ethnographic research and textual analysis of song-and-dance sequences of Bollywood films and reality shows, the chapter explores the transformation of the mythopoetic bhakti rasa of classical dances into the remix of Bollywood dances. It argues that “item numbers” and reality shows shape new gender codes in contemporary India and open up new debates on respectability, gender, and nation.
Dismantling the Genre
Authors: Benthaus Elena 
Published: November 2018

AbstractThe American television show So You Think You Can Dance (SYTYCD) is commonly referred to in the scholarship as a reality dance competition, a reality talent show, or simply as reality television. Instead of looking at the competitive aspect of SYTYCD and its relation to the genre of reality television, this chapter focuses on the show’s inherent intertextuality, specifically in relation to the early American popular entertainment genres of vaudeville and melodrama. It argues that vaudeville performance aesthetics and melodramatic performance modes are attractions on display, which produce what media scholar Henry Jenkins refers to as “affective immediacy” and “affective intensification” as part of the spectatorship experience that goes beyond the competitive aspect of SYTYCD. It focuses on the dance routines as well as audience responses to these routines from the SYTYCD dance fan community on YouTube.
Dancing with the Asian American Stars
Authors: Wong Yutian 
Published: November 2018

AbstractMargaret Cho is a Korean American comedian and television personality who has made a career out of turning a series of failures into material for her public persona. In 2010 Cho appeared as a celebrity contestant on the reality television dance competition Dancing with the Stars, where she attempted to critique the structure of the dance competition and the expectations for performing proper Asian femininity. This chapter examines Cho’s failure to win as an attempt to rewrite the conditions of Asian American success, which is most often construed in narrowly defined terms of model minority excellence in opposition to complete failure.
“We’ll Rumble ’em Right”
Authors: Zhu Ying , Belgrad Daniel 
Published: November 2018

AbstractIn cultural studies, attention to dance enables a reassessment of the politics of cultural forms, based on a recovery of the embodied subject as the center of meaning-making. Revisited in this light, the film West Side Story is revealed as a cultural defense of youth and play. While the adults in the film work persistently to force the Jets and Sharks into one of two binary categories (serious and mature adults, or innocent and victimized children), the youths make common cause in resisting these categories, through forms of competitive play that sprawl from the playground into the streets, beyond children’s games to the taunting and flaunting and brawling that adult discourses labeled “juvenile delinquency.” Examining three dances, the chapter argues that in West Side Story, as long as conflict is structured as a competition, it remains a cooperative and ordered enterprise. But when competition is disrupted, social frustrations erupt into fatal violence.