bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intranodal Hemangioma: Case Report and Systematic Review
Authors: Kumar Bitesh , Kulkarni Kaushal , Kumar Dhua Anjan , Prabudh Goel , Kumar Yadav Devendra , Vishesh Jain , Sandeep Agarwala , Kavneet Kaur , Devasenathipathy Kandasamy 
Published: November 2024

ABSTRACT

Background:
Intranodal hemangiomas are rare benign vascular tumors of the lymph nodes, often misdiagnosed as malignant lymphadenopathies due to their clinical and radiological features. This case report and systematic review aim to elucidate the epidemiology, clinical profile, and therapeutic interventions for intranodal hemangioma, enhancing diagnostic accuracy and management.

Methods:
A systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Searches were conducted in PubMed, Scopus, Web of Science, and Google Scholar up to March 15, 2024, using keywords like “intranodal hemangioma,” “primary intranodal hemangioma,” “nodal hemangioma,” “vascular tumor,” and “lymph node hemangioma.” Inclusion criteria included studies on clinical presentation, diagnostic strategies, and therapeutic interventions for intranodal hemangioma in patients of all ages. Excluded were reviews, opinion pieces, non-English studies, cases of hemangioendothelioma, sclerosing hemangioma, and animal studies. Key aspects analyzed included demographics, clinical presentation, management strategies, and histopathological findings.

Results:
Our case involves a 3-year-old female with a submandibular mass, initially diagnosed with hemangioma. After no response to beta-blocker therapy and conflicting imaging results, surgical excision was performed. Histopathology confirmed intranodal hemangioma. From 233 records, 19 publications (36 patients, including our case) met the inclusion criteria. The review shows common clinical presentations as painless, slowly enlarging lymph nodes, primarily in the cervical and axillary regions. Diagnostic challenges often require imaging and biopsy to differentiate from malignancies.

Conclusion:
Recognizing intranodal hemangiomas, particularly in childhood, is crucial to prevent misdiagnosis and inappropriate treatment. The rarity of these tumors in childhood and their clinical presentation similar to malignancies in older patients make diagnosis challenging without widespread awareness. Surgical excision remains the mainstay of both diagnosis and treatment, often leading to favorable outcomes.
Non-invasively differentiate non-alcoholic steatohepatitis by visualizing hepatic integrin αvβ3 expression with a targeted molecular imaging modality
Authors: Huang Xiao-Quan , Wu Ling , Xue Chun-Yan , Rao Chen-Yi , Fang Qing-Qing , Chen Ying , Xie Cao , Rao Sheng-Xiang , Chen Shi-Yao , Li Feng 
Published: November 2024

BACKGROUND
Non-invasive methods to diagnose non-alcoholic steatohepatitis (NASH), an inflammatory subtype of non-alcoholic fatty liver disease (NAFLD), are currently unavailable.
AIM
To develop an integrin αvβ3-targeted molecular imaging modality to differentiate NASH.
METHODS
Integrin αvβ3 expression was assessed in Human LO2 hepatocytes Scultured with palmitic and oleic acids (FFA). Hepatic integrin αvβ3 expression was analyzed in rabbits fed a high-fat diet (HFD) and in rats fed a high-fat, high-carbohydrate diet (HFCD). After synthesis, cyclic arginine-glycine-aspartic acid peptide (cRGD) was labeled with gadolinium (Gd) and used as a contrast agent in magnetic resonance imaging (MRI) performed on mice fed with HFCD.
RESULTS
Integrin αvβ3 was markedly expressed on FFA-cultured hepatocytes, unlike the control hepatocytes. Hepatic integrin αvβ3 expression significantly increased in both HFD-fed rabbits and HFCD-fed rats as simple fatty liver (FL) progressed to steatohepatitis. The distribution of integrin αvβ3 in the liver of NASH cases largely overlapped with albumin-positive staining areas. In comparison to mice with simple FL, the relative liver MRI-T1 signal value at 60 minutes post-injection of Gd-labeled cRGD was significantly increased in mice with steatohepatitis (P < 0.05), showing a positive correlation with the NAFLD activity score (r = 0.945; P < 0.01). Hepatic integrin αvβ3 expression was significantly upregulated during NASH development, with hepatocytes being the primary cells expressing integrin αvβ3.
CONCLUSION
After using Gd-labeled cRGD as a tracer, NASH was successfully distinguished by visualizing hepatic integrin αvβ3 expression with MRI.
Low level of hepatitis B viremia is associated with increased risk of hepatocellular carcinoma in compensated cirrhotic patients
Authors: Lin Wei-Chun , Lin Ke , Li Ming-Kai , Liu Xiao , Huang Yi-Fei , Wang Xing , Wu Bin 
Published: November 2024

BACKGROUND
Whether patients with compensated cirrhosis and low-level viremia (LLV) of hepatitis B should receive antiviral therapy (AVT) is still controversial, and published results are inconsistent.
AIM
To investigate the link between LLV in compensated cirrhosis and prognosis concerning hepatocellular carcinoma (HCC), decompensation, and liver-related events.
METHODS
The PubMed, EMBASE, and Cochrane Library databases were searched up to March 5, 2023. Outcomes of interest were assessed by pooled hazard ratios (HRs). The study was registered with PROSPERO (CRD42023405345).
RESULTS
Six cohort studies representing 3155 patients were included. Compared with patients with undetectable HBV DNA, patients with LLV was associated with increased risk of HCC (HR: 2.06, 95%CI: 1.36-3.13; Q -statistic-P = 0.07, I 2 = 51%) regardless of receiving AVT or not (AVT group: HR: 3.14; 95%CI: 1.73-5.69; Q -statistic-P = 0.60, I 2 = 0%; un-AVT group: HR: 1.73, 95%CI: 1.09-2.76; Q -statistic-P = 0.11, I 2 = 50%). The pooled results showed no statistical association between LLV and decompensation of cirrhosis (HR: 2.06, 95%CI: 0.89-4.76; Q -statistic-P = 0.04, I 2 = 69%), and liver-related events (HR: 1.84, 95%CI: 0.92-3.67; Q -statistic-P = 0.03, I 2 = 72%), respectively. Grading of Recommendations Assessment, Development and Evaluation assessment indicated moderate certainty for HCC, very low certainty for decompensation of cirrhosis and liver-related clinical events.
CONCLUSION
LLV in compensated cirrhotic patients is associated with increased risk of HCC, higher tendency for hepatic decompensation and liver-related events. Closer screening of HCC should be conducted in this population.
Pituitary stalk interruption syndrome complicated with liver cirrhosis: A case report
Authors: Chang Min , Wang Shi-Yu , Zhang Zi-Yu , Hao Hong-Xiao , Li Xin-Gang , Li Jing-Jing , Xie Yao , Li Ming-Hui 
Published: November 2024

BACKGROUND
Pituitary stalk interruption syndrome (PSIS) is a rare disorder, often characterized by delayed growth and development, short stature, and hypogonadism as the main clinical manifestations. It is not clear whether PSIS can lead to liver cirrhosis.
CASE SUMMARY
This paper reported a case of liver cirrhosis of unknown origin. The patient was admitted to Beijing Ditan Hospital Affiliated to Capital Medical University in November 2023. The diagnosis of PSIS complicated with liver cirrhosis was established after a series of blood tests and pituitary magnetic resonance imaging examination.
CONCLUSION
We also reviewed the literature from both domestic and international sources to deepen the clinical understanding of PSIS in conjunction with liver cirrhosis among medical practitioners.
Knowledge and attitude of pharmacy students towards HIV treatment and prophylaxis in Davao City, Philippines
Authors: Tobias Ela Mae V. , Sibay Allena Rose S. , Mahinay Angel Ann T. , Montaño Annalee M. , Gabucan Von Jay Maico G. 
Published: November 2024

Pharmacy students significantly contribute to HIV management as future registered pharmacists. To contribute meaningfully, pharmacy students must be knowledgeable and have positive attitudes towards HIV treatment and prophylaxis. The aim is to investigate the levels of knowledge and attitude of undergraduate pharmacy students towards HIV treatment and education to identify key areas of improvement.
Methods: The study used a quantitative research design with a structured survey based on published studies. Undergraduate pharmacy students from various schools in Davao City were invited to participate and provide informed consent. Descriptive and inferential statistics were used after obtaining data.
Results: Pharmacy students in Davao City were found to have high overall knowledge (mean = 64.29%) and a high overall attitude (mean = 3.88). Knowledge about HIV treatment and prophylaxis did not correlate with the respondents' attitudes towards it. Furthermore, it was found that there is a significant difference in knowledge and attitude based on year level and school (< 0.000).
Conclusion: The knowledge and attitude of undergraduate pharmacy students toward HIV treatment and prevention were high, indicating favourable results. However, improvements and training must continue to enhance their knowledge and attitude and reduce misconceptions and stigma. Collaboration with key stakeholders is essential to ensure the implementation of intervention programmes.
A POLITICAL DISCOURSE ANALYSIS OF THE PHILIPPINE POLITICIANS’ SPEECH ACTS ON PEOPLE’S INITIATIVE: A FORENSIC LINGUISTICS STUDY
Authors: Obenza Brandon N. , Caloc Louie Jay R. , Baradillo Danilo G. 
Published: November 2024

This political discourse analysis aims to unveil the speech acts and FTAs employed by Philippine politicians, their contributions to the persuasive power of political discourse, and their pragmatic implicatures on the People’s Initiative. This study utilized a qualitative research design using forensic linguistics through political discourse analysis, with corpus linguistics of 16 political speeches chosen through purposive sampling. The findings revealed that 18% of the discourse falls under FTAs, 42% for speech acts, 20% for persuasive power contribution, and 20% for pragmatic implicatures. This purports the complex relationships that exist between language, power, and persuasion in the political context.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0785/a.php" alt="Hit counter" /></p>
ANALYSIS OF FINANCIAL PERFORMANCE IN VARIOUS SECTORS: APPLICATION OF THE BENEISH M-SCORE MODEL IN CASABLANCA STOCK EXCHANGE MOROCCO
Authors: Soufiane Ben Nokro , Moad El Kharrim 
Published: November 2024

<p>This paper evaluates the financial performance of companies from different sectors on the Moroccan financial market, using the Beneish M-Score model. Initially developed to detect financial anomalies, the M-Score has evolved into a tool for assessing companies' overall financial performance and earnings quality. By analyzing financial indicators such as profitability, liquidity and operational efficiency, this study compares the financial dynamics of companies in sectors such as food, technology and transportation. The results highlight significant differences in performance, revealing both strengths and weaknesses in companies' financial management. The study also provides a comparison with industry standards, and offers recommendations for improving the assessment of financial performance using financial indicators and the M-Score.</p><p> </p><p><strong>JEL: </strong>G32, M41, L25</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0778/a.php" alt="Hit counter" /></p>
SPEAKING HABITS OF THE UNDERGRADUATE LEVEL EFL LEARNERS: A SURVEY
Authors: Pathan Md. Arif Khan 
Published: November 2024

<p>Speaking skills are the most important and dominant skills of a language that a language learner can never avoid or underestimate. From academic life to professional life, strong speaking skills help students in all aspects of their lives. Good speaking skills also act as indicators of knowing a language. In spite of knowing the importance of having strong speaking skills, unluckily, the majority of the EFL learners are found very weak and incompetent in speaking. The current study explored the speaking habits of undergraduate-level EFL learners through a five-point Likert-scale survey and found that the learners are very careless about practicing and improving their speaking skills. They have lots of opportunities and resources around them, but they do not utilize them to practice these skills. As a result, they could not develop good speaking habits in their everyday lives. </p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0733/a.php" alt="Hit counter" /></p>
REVISITING PUPPETS TO TEACH ENGLISH TO CHILDREN: MODEL ACTIVITIES TO FOSTER CLASSROOM ORAL INTERACTION USING PUPPETS
Authors: Mogollon Joibel Tadea Gimenez 
Published: November 2024

<p>Puppetry, as an educational resource, has been used for years to create a dynamic and interactive learning environment that encourages creativity, active oral participation and language fluency development. In a world where the use of technological tools, digital materials, apps and virtual classrooms have changed the dimension of education, making classes more dynamic and obliquus, puppets are still valuable in the class, as multiple research works have shown. For that reason, we revisited the use of puppets as a pedagogical tool in the English classroom, specifically to foster oral interactions in the English classes of a group of pre-schooling students. In that group, we observed that even though the teacher used multiple resources and activities (such as games, songs, act outs and more), some students did not participate in the oral interaction activities. We decided to design a set of activities mediated by impersonated puppets to foster oral interaction in the class. In this work, we presented the steps for designing those activities and a theoretical foundation for that design. The findings of its application are a matter of further research.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0745/a.php" alt="Hit counter" /></p>
EXPLORING THE ROLE OF L1 LITERACY SKILLS IN L2 READING COMPREHENSION AND VOCABULARY DEVELOPMENT AMONG SENIOR HIGH SCHOOL STUDENTS IN GHANA
Authors: Arthur Rebecca 
Published: November 2024

This study investigated the relationship between first language (L1) literacy skills and second language (L2) reading comprehension and vocabulary development among students in Ghana. The study was grounded in Cummin’s (1970) Linguistic Interdependence Theory (LIT). The qualitative approach was adopted, and three instruments- focus group discussions, interviews and classroom observations- were used to obtain data from the sample of 300 secondary school students and 40 teachers. The researcher assessed participants' views in L1 literacy domains (phonological awareness, orthographic knowledge, and reading fluency) as well as their views on L2 (English) reading comprehension and vocabulary. The findings revealed a significant positive correlation between students' L1 literacy skills and their achievement in L2 reading comprehension and vocabulary. Those with more advanced abilities in their native language consistently demonstrated higher levels of reading comprehension and broader English vocabulary knowledge. This underscores the critical role of strong foundational literacy in the first language as a precursor to successful second language acquisition. The study also identified key instructional strategies that could help bridge the gap for ESL learners, such as explicit instruction in L1 literacy, structured opportunities for cross-linguistic transfer, and the incorporation of culturally relevant, mother-tongue materials into the curriculum. The implications of these findings for policymakers, curriculum designers, and teachers working to improve educational outcomes for linguistically diverse student populations are discussed.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0799/a.php" alt="Hit counter" /></p>
EXPLORING THE IMPACT OF LINGUISTICALLY INFORMED FORMATIVE ASSESSMENTS ON EFL PROFICIENCY AMONG GREEK LEARNERS: A PILOT STUDY ACROSS PRIMARY AND SECONDARY EDUCATION ESTABLISHMENTS
Authors: Fountoulakis Michail St. 
Published: November 2024

This pilot study explores the impact of linguistically informed formative assessments on English as a Foreign Language (EFL) proficiency among Greek learners, focusing on primary and secondary education establishments. Leveraging five years of research data collected between 2017 and 2022 from over 360 students across urban and rural regions in Greece, this study examines how integrating linguistic theory into formative assessments can enhance students' morphological and syntactical proficiency. Using a mixed-methods approach, both quantitative and qualitative data were gathered through standardized language proficiency tests, linguistically informed assessments, and semi-structured interviews with students and educators. The findings indicate that students exposed to these linguistically informed assessments demonstrate significant improvements in EFL proficiency, particularly in verb conjugation and sentence structure, with enhanced long-term retention and application in both written and spoken English. These results underscore the potential for linguistically informed formative assessments to be a powerful tool in EFL pedagogy, with implications for curriculum design and instructional practices in Greek educational settings. The study also identifies areas for future research, including broader applications across diverse educational contexts and the scalability of such assessments.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0760/a.php" alt="Hit counter" /></p>
STUDENTS’ KNOWLEDGE OF INTEGRATION OF GEOGEBRA IN LEARNING MATHEMATICS IN LOWER SECONDARY SCHOOLS IN UGANDA
Authors: Karungi Glorious , Batiibwe Marjorie Sarah Kabuye 
Published: November 2024

The use of technology in the pedagogical process is growing at a phenomenal rate and has revolutionized the way students learn. As a result, there is a need for integrating technology into students’ mathematical activities. GeoGebra is a technology software that supports teaching and learning mathematics, especially geometry, algebra, and statistics. This study investigated the students’ knowledge of the integration of GeoGebra in learning mathematics in lower secondary schools in Wakiso District, Uganda. The study utilized quasi-experimental and cross-sectional designs with 42 senior two students in the experimental and 43 in the control group. Data were collected using pre-tests, post-tests, and questionnaires to identify the students’ difficult geometric concepts when learning mathematics, establish the impact of GeoGebra-based training on the students’ learning, and examine the relationship between students’ perceived ease of use of GeoGebra and its integration in learning mathematics. Independent samples t-test, Pearson's linear correlation, and descriptive statistics such as mean, standard deviation, percentages, and frequencies were employed to analyze the data. The study revealed that reflection on the Cartesian plane was the most abstract geometric concept to learn. The results further revealed a statistically significant mean difference between pre-test and post-test scores in favour of the experimental group after the intervention. Furthermore, a moderately significant positive linear correlation existed between students’ perceived ease of use of GeoGebra and its integration in learning reflection on the Cartesian plane. Therefore, the study recommends urgently training students to incorporate this interactive educational software into their mathematics learning.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0871/a.php" alt="Hit counter" /></p>
ENHANCING TEACHER PRACTICES IN ASSESSING FUNCTIONAL PERFORMANCE OF STUDENTS WITH AUTISM SPECTRUM DISORDER (ASD): AN EMPIRICAL PERSPECTIVE
Authors: Malasi-Nyali Maghuwa Flora , Oracha Adoyo Peter 
Published: November 2024

Youth students with Autism Spectrum Disorder (ASD) are at higher risk of functional skills deficiency, which presents a barrier to the acquisition of academic skills. This study examines teachers’ practices in determining the functional performance of students with ASD in stage-based education pathways in Kenya. A quantitative research design was employed, involving 47 teachers and 76 students with ASD from various primary schools. Data were collected using a self-administered rating scale for teachers and a modified version of the Vineland Adaptive Behaviour Scales for students. Descriptive and sequential regression analyses were conducted to evaluate teacher practices and their impact on students’ functional skills. Findings show that the identification and use of instructional resources were the most frequently performed practices among teachers, while the assessment of functional skills was the least. The study found significant correlations between teacher practices and students’ functional skill acquisition, particularly communication skills. However, the relationships among teacher practices were generally weak, indicating a lack of integration in their approaches. The study concludes that a comprehensive approach, incorporating multiple assessment practices, is essential for improving student outcomes. Recommendations include targeted professional development for teachers, standardized assessment practices, and increased collaboration with parents to support functional skill development in students with ASD. These findings underscore the need for enhanced training and resource access to optimize educational outcomes within the Competency-Based Curriculum framework.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0717/a.php" alt="Hit counter" /></p>
THE RELATIVE CONTRIBUTION OF ACADEMIC PASSION TO ACADEMIC WELL-BEING AMONG NURSING STUDENTS
Authors: Massalha Abed Elslam Mohamad , Iktilat Khalil abd 
Published: November 2024

The current study aimed to reveal the relative contribution of academic passion to the academic well-being among nursing students. To achieve the study objectives, a sample of (143) male and female students from Palestinian students inside the Arabs (48) was selected by using the available sample method for the summer semester of the academic year 2023-2024. The academic passion scale and the academic well-being scale were applied to them. The results showed that the level of academic well-being was within the high level and that there were no statistically significant differences at (=0.05) in the responses of the sample members on the academic well-being scale attributed to the gender and academic level. The results also showed that whenever the obsessive academic passion increases by a standard unit, the academic well-being increases (0.489), and whenever the harmonious academic passion increases by a standard unit, the academic well-being increases (0.297).<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0725/a.php" alt="Hit counter" /></p>