bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prophylactic Fucose can Alleviate Lipopolysaccharide-Induced Cholestatic Liver Injury in Neonatal Rats
Authors: Baysal Bora , Tüzün Funda , Engür Defne , Özbal Seda , Ergür BekirUğur , İşcan Burçin , Yücesoy Ebru , Duman Nuray , Özkan Hasan , Kumral Abdullah 
Published: August 2019

Objectives Cholestasis is a common disease of the liver in premature infants and no specific preventive treatment is currently available. Fucose, one of the monosaccharide building blocks of human milk oligosaccharides, may prevent cholestatic hepatic injury by various mechanisms. The aim of this study was to investigate the protective effect of fucose treatment after endotoxin-induced cholestasis in a rat model.
Methods Wistar rat pups were divided into four groups as: group I, control group; group II, fucose-supplemented group; group III, lipopolysaccharide (LPS)-administered group, and group IV, LPS-exposed and fucose-supplemented group. Fucose was given 100 mg/kg i.p. every other day between PN5–17. LPS was administered on PN19 to establish endotoxin-induced cholestasis model. On PN21, animals were sacrificed to evaluate liver cell damage and apoptosis.
Results Fucose supplementation significantly improved the biochemical parameters that deteriorated in LPS-administered group, significantly increased the expression of bile salt export pump, reduced the number of apoptotic cell death, and greatly prevented LPS-induced cholestatic hepatic injury.
Conclusion Given our results, fucose may be useful in reducing hepatic injury and might possess clinical relevance for the preventive treatment of inflammation-induced cholestatic injury in newborns.
Interpretations of the Term “Watershed Line” Used as Reference for Volar Plating
Authors: Bergsma Minke , Doornberg Job N. , Hendrickx Laurent , Hayat Batur , Kerkhoffs Gino M.M.J. , Jhadav Bhavin , Jaarsma Ruurd L. , Bain Gregory I. 
Published: August 2019

Objective The objective of this systematic review is to provide an overview of all interpretations of the definition of the watershed line used in literature.
Methods The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines were followed for this review. A comprehensive search was performed for definitions of the watershed line given in literature. A total of 32 studies giving an explicit interpretation of the definition of the watershed line or anatomical reference for plate positioning in writing and/or imaging were included.
Results In 32 studies, we found eight different landmarks used to refer to the watershed line or correct plate positioning. Five studies used two different soft tissue landmarks. Six different bony landmarks were described in 24 studies. These could further be subdivided into three anatomical interpretations, described in seven studies, in which the term “watershed line” is explained as a distinguishable anatomical line, and two surgical interpretations, described in 15 studies, which are purely reflecting the optimal location of the volar plate. One interpretation of the watershed line described in two studies combined both anatomical and surgical landmarks.
Conclusion The (mis)interpretation of the definition of the term “watershed line” as described by Orbay is subject to the type of landmarks and purpose used: soft tissue or bony landmarks and an anatomical or a surgical purpose. A clear distinction can be made between interpretations using bony landmarks, as the true watershed line is defined and definitions using soft tissue landmarks, which might represent the reference points surgeons use in clinical practice.
Spinal Dural Arteriovenous Fistula-Induced Myelopathy: Rare and Commonly Missed but Treatable Nevertheless
Authors: Sharma Manish , Mathur Ankit 
Published: August 2019

Abstract
Objectives To highlight spinal dural arteriovenous fistula (dAVF) as a treatable cause of myelopathy that is often misdiagnosed. Clinical progression, hallmark radiological findings, and postoperative course of recovery are studied.
Patients and Methods Three patients with spinal dAVF were included in the study. Retrospective evaluation of the progression of disease and treatment received was done. Two of them were managed by surgical ligation of fistula, and the third patient was under observation because of lack of localizing symptoms.
Results Two of the three patients had previously been diagnosed with multiple sclerosis, and one of them had received steroids. The third case was easily diagnosed at an early stage as the center had become adequately sensitized about the radiologic findings. After surgical excision of the fistula, both operated cases recovered steadily but significantly, regained significant neurologic functions despite being operated at an advanced stage.
Conclusion Spinal dAVF is a rare entity. They have the potential to cause severe morbidity in the form of myelopathic changes in the cord and paraparesis in advanced stages. They can be misdiagnosed even after a magnetic resonance imaging evaluation as the appearance of dilated perimedullary veins and cord changes are not easy to interpret and require specific understanding of the radiologic changes that may occur. However, once diagnosis has been established, an early interruption of the fistula leads to a good clinical recovery.
The evidence ecosystem in South Africa: growing resilience and institutionalisation of evidence use
Authors: Stewart Ruth , Dayal Harsha , Langer Laurenz , van Rooyen Carina 
Published: August 2019

AbstractThe evidence-informed approach to policy-making and implementation is, at its core, about better decisions for a better future. It is focused on the effective use of scarce resources, on avoiding harm and maximising good. It is grounded in principles of equity and equality, of accountability and transparency. Given these characteristics, for those of us who work in this field, there is arguably a moral, economic, social and political case for paying closer attention to evidence-informed decision-making ecosystems in the South. Evidence-based policy and implementation, or evidence-informed decision-making in line with the most recent thinking, is often framed from two inter-related but limited perspectives: first, it is viewed as an approach that has originated from ‘developed’ Northern countries, and second, it is conceptualised as a technical intervention. However, there has been a shift in how the approach is conceived, moving away from assumptions that it is an intervention implemented from outside, from the North, for the benefit of the South. As part of this shift, certain initiatives in Africa have gained greater momentum. It is in acknowledging that there are different ways to think (epistemic diversity) about Southern evidence-informed decision-making, that this work has arisen. It seizes on the opportunity to view evidence-informed decision-making in a new light, exploring the evidence ecosystems in the South as systems strongly influenced by, but not defined by, Northern stimuli, including, but not limited to, technical interventions. This work set out to describe the evidence ecosystem in South Africa. In doing so, it finds that the ecosystem is increasingly resilient despite some limitations. It has strong structural foundations, includes many diverse organisations, is supported by not inconsiderable investment, is enabled by growing and significant capacity, contains iterations and innovations, and last but not least, incorporates complexity that gives the ecosystem resilience. The work demonstrates, through its focus on South Africa’s evidence ecosystem, that the global movement has much to learn from the South.
HumanGNPTABstuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum
Authors: Han Tae-Un , Root Jessica , Reyes Laura D. , Huchinson Elizabeth B. , Hoffmann Johann du , Lee Wang-Sik , Barnes Terra D. , Drayna Dennis 
Published: August 2019

SignificanceStuttering is a common neurodevelopmental disorder. However, the neurological causes of this disorder are poorly understood. The disorder is highly genetic, and recent discoveries have found several genes involved in this disorder, but how these lead to the unique clinical features of stuttering has been unknown. We have shown that mice carrying human stuttering mutations display vocalization deficits that recreate the salient features of human stuttering. In these mice, we have used several different complementary techniques to identify a specific deficit in astrocytes, a type of glial cell prominent in white matter tracts, particularly in the corpus callosum of these mice. These findings suggest astrocytes as a site of the neuropathology, leading to a deficit in interhemispheric connectivity in stuttering.
Akt phosphorylation of neuronal nitric oxide synthase regulates gastrointestinal motility in mouse ileum
Authors: Guerra Damian D. , Bok Rachael , Vyas Vibhuti , Orlicky David J. , Lorca Ramón A. , Hurt K. Joseph 
Published: August 2019

SignificanceNeuronal nitric oxide synthase (nNOS) is believed to be activated primarily by Ca2+/calmodulin. Activation of nNOS by phosphorylation similar to endothelial NOS has been suggested but is technically difficult to confirm in vivo. We developed a knock-in mouse with nNOS serine1412 mutated to alanine and show using mouse ileum that nNOS phosphoserine1412 regulates gastrointestinal smooth muscle relaxation and functional motility. nNOS is phosphorylated by the protein kinase Akt during submaximal neuronal depolarization to augment NO-cGMP signaling in a manner tuned toward resting intracellular Ca2+levels. Phosphorylation at nNOS serine1412 represents a previously unrecognized physiologic mechanism of nNOS regulation linking neuronal depolarization to gastrointestinal motility and clarifies characteristics of neuronal NO production.
Generalized size scaling of metabolic rates based on single-cell measurements with freshwater phytoplankton
Authors: Zaoli Silvia , Giometto Andrea , Marañón Emilio , Escrig Stéphane , Meibom Anders , Ahluwalia Arti , Stocker Roman , Maritan Amos , Rinaldo Andrea 
Published: August 2019

Significance
Empirical laws predicting metabolic rates of a species by its average body mass neglect intraspecies variability arising from the range of physiologically feasible rates and phenotypic heterogeneity. We describe an exploratory experimental test of a theory that explicitly accounts for such variations. We show, by single-cell joint measurements of mass and uptake rates, how marginal distributions of mass and rates collapse onto a common master distribution for species spanning 3 orders of magnitude in cell volume. These results demonstrate the potential of a generalized scaling theory that goes beyond population averages to incorporate within-species variation.
High-efficiency triple-resonant inelastic light scattering in planar optomagnonic cavities
Authors: Pantazopoulos Petros Andreas , Tsakmakidis Kosmas L , Almpanis Evangelos , Zouros Grigorios P , Stefanou Nikolaos 
Published: August 2019

Abstract
Optomagnonic cavities have recently been emerging as promising candidates for implementing coherent photon-magnon interactions, for applications in quantum memories and devices, and next generation quantum networks. A key challenge in the design of such cavities is the attainment of high magnon-mediated optical-to-optical conversion efficiencies, which could, e.g., be exploited for efficient optical interfacing of superconducting qubits, as well as the practicality of the final designs, which ideally should be planar and amenable to on-chip integration. Here, on the basis of a novel time-Floquet scattering-matrix approach, we report on the design and optimization of a planar, multilayer optomagnonic cavity, incorporating a cerium-substituted yttrium iron garnet thin film, magnetized in-plane, and operating in the triple-resonant inelastic light scattering regime. This architecture allows for magnon-mediated optical-to-optical conversion efficiencies of about 5% under realistic conditions, which is orders of magnitude higher than that attained in alternative optomagnonic designs. Our results suggest a viable way forward for realizing practical information inter-conversion, with high efficiencies, between microwaves, strongly coupled to magnons, and optical photons, as well as a platform for fundamental studies of classical and quantum dynamics in magnetic solids and for the implementation of futuristic quantum devices.
Hyperuniformity and static structure factor of amorphous silicon in the infinite-wavelength limit
Authors: Dahal Devilal , Atta-Fynn Raymond , Elliott S. R. , Biswas Parthapratim 
Published: August 2019

Abstract
The static structure factor of amorphous silicon (a-Si) models, containing 400,000 atoms with a density of 2.25 g⋅cm−3, has been studied by generating atomistic models using classical molecular-dynamics simulations. The behavior of the structure factor, S(Q), in the limit Q → 0, is examined to determine the degree of hyperuniformity in a-Si and is compared with the results with those from earlier simulations and small-angle X-ray scattering experiments. The study suggests that the computed value of the relative variance of the number of atoms at large distances, and hence S(Q → 0), lies in the range from 0.00736 to 0.00758, which is very close to the experimental value of 0.0076 ± 0.0005, obtained from an extrapolation of transmission X-ray scattering data in the small-angle region. The non-zero value of the structure factor S(0) in a-Si can be attributed to density fluctuations on a very large length scale, which is a characteristic property of the structural and topological ordering of silicon atoms in the amorphous state.
Domain walls in strontium titanate
Authors: Stephen Hellberg C. 
Published: August 2019

AbstractDensity functional theory calculations of twin-domain walls in strontium titanate are presented. The two possible domain walls are characterized. The domain wall type is set by the relative phase of the octahedral rotations in the body-centered-tetragonal SrTiO3on either side of the domain wall. The width of the domain walls is estimated to be approximately 3 nm.
Quantum Search on Networks
Authors: Boettcher Stefan 
Published: August 2019

Abstract
We find a lower bound on the computational complexity of Grover’s quantum search algorithms in low-dimensional networks using the renormalization group (RG). It highlights the competition between Grover’s abstract algorithm, i.e., a rotation in Hilbert space, and quantum transport in an actual geometry. It can be characterized in terms of the quantum walk dimension

d
w
Q

and the spatial (fractal) dimension df
or, alternatively, the spectral dimension of the network, ds
, even when translational invariance is broken.
On selected issues of Boolean function application in symmetric key cryptography against side channel attacks
Authors: Seman Kamaruzzaman , Roslan Muhammad Fahim , Ab Halim Azni Haslizan , Syam Mohd Sayuti M Nor Azizi 
Published: August 2019

AbstractBoolean function plays a prominent role in building strong cryptography algorithm especially in symmetric block cipher. However, there may be some issues and conflicting criteria which prevent such a Boolean function to resist the algorithm to all known attacks. Within this work, the nonlinearity and correlation immunity issues of Boolean function is discussed followed by complementary counter measure against side channel attack especially differential power attack (DPA)
Naive Bayes classifier for infant weight prediction of hypertension mother
Authors: Desiani Anita , Primartha Rifkie , Arhami Muhammad , Orsalan Osvari 
Published: August 2019

Abstract
Classification is one method of data analysis in data mining that is used to form a model in order to describe the appropriate data class or model that predicts data trends. The Usage of classification has been applied in various areas, including in health areas. One of the classification methods used is Naive Bayes. This study aims to predict the weight of infants in maternal hypertensive and nonhypertensive conditions with Naive Bayes method. Data were taken as many as 219 data from pregnant women based on the medical record in Obstetrics and Gynecology of Muhammadiyah Palembang Hospital from January 1017 until September 2017. Data is divided into two groups, 188 for training data and 31 data for testing data. The performance data analysis was using WEKA and the results showed that the Naive Bayes’s accuracy is 80.372%. the accuracy score means Naive Bayes works well to predict the weight of infants in maternal hypertensive and nonhypertensive mothers. The result is expected to be a reference for others research by comparing it with other classification methods and incorporating other factors in pregnancy and multiple births or other factors.
Joint life insurance based on Gompertz assumptions and interest rate affected by the excange rate
Authors: Zayanti Des Alwine , Kresnawati Endang Sri , Megah Mulya 
Published: August 2019

Abstract
This paper discussed about Calculation of joint life insurance premiums based on Gompertz mortality assumptions that affect the probability of joint insurance participants. One important variable in calculating premiums and reserves is interest rates. The foreign exchange rate is the price of a currency if exchanged with another countrys currency. Depreciation in the foreign exchange rate causes fluctuations in interest rates which ultimately affect the calculation of premiums for joint life insurance. Based on the calculation results, the greater the depreciation value, the greater the interest rate. This will increase risk for insurance companies. Calculation of insurance premiums that are affected by dollar fluctuations, is expected to be able to obtain calculations that are in accordance with the world economic trends.
A non-proportional hazards model with time-dependent variables for under-five mortality in Indonesia
Authors: Faruk Alfensi , Syahputra Erlan , Cahyono Endro Setyo , Aisyah Sari Mutiara 
Published: August 2019

AbstractCox proportional hazards (PH) is known as the most popular model for the analysis of multivariate survival data. The main assumption of the model is that the hazard ratio among any two individuals in the population is constant over time. The violation of this assumption, however, may cause serious issues such as overestimation or underestimation of hazard risks and reducing the power of related statistical tests. The main objective of this research, therefore, is to extend the Cox PH model by adding time-dependent variables into the model to cope with the presence of non-PH. The proposed model, moreover, is applied to under-five mortality data based on Indonesian Demographic and Health Survey (IDHS) 2012. The results showed that the Akaike’s Information Criterion (AIC) and Bayesian Information Criterion (BIC) values of the extended Cox model with time-dependent variables are much lower than the Cox PH model. This means that the extended Cox model can increase significantly the goodness-of-fit of the Cox PH model to under-five mortality data in Indonesia.
Pattern recognation for study period of student in Mathematics Department with C4.5 algorithm data mining technique at the Faculty of Mathematics and Natural Science Universitas Sriwijaya
Authors: Yahdin Sugandi , Desiani Anita , Amran Ali , Rodiah Desty , Solehan  
Published: August 2019

Abstract
The study period pattern of student can facilitate the stakeholders to improve education services in their institutions. This study investigated the study period pattern of the graduated students from January 2014 until February 2018 with the C4.5 algorithm. The obtained data from three academic years 2011, 20112, and 2013 is 140 students with 18 frequently repeated subjects. The total attributes that used in the study are 19 attributes. These attributes contain 18 frequently repeated subject and one attribute for the label is from the study period of a student (punctual or not punctual). This study used the method of K-fold cross-validation with K = 10 and the percentage split with the percentage is 66% to measure the performance of the algorithm C4.5. The results of both methods showed that the subjects that affect sequentially in the study period of the student are a complex function, numerical methods, introduction to computer science, computer programs and basic physics. The accuracy of the results obtained from both the training process K-fold cross-validation amounted to 84.29% and 72.92% for percentage split. It shows that algorithm C4.5 is quite well in predicting the pattern of the study period of a student majoring in mathematics, Department of Universitas Sriwijaya.
Limiting Distribution of the Bootstrap Parameter Estimator of a Second Order Autoregressive Model
Authors: Suprihatin Bambang , Cahyono Endro Setyo , Faruk Alfensi 
Published: August 2019

Abstract
This paper is the extension of our research about asymptotic distribution of the bootstrap parameter estimator for the AR(1) model. We investigate the asymptotic distribution of the bootstrap parameter estimator of a second order autoregressive AR(2) model by applying the delta method. The asymptotic distribution is the crucial property in inference of statistics. We conclude that the bootstrap parameter estimator of the AR(2) model asymptotically converges in distribution to the bivariate normal distribution.
Preparation and characterization of epoxy resin bonded magnet prepared by using jet milled NdFeB
Authors: Eka Sari Meiliyana , Ramlan  , Mulyadi  
Published: August 2019

Abstract
The preparation of bonded magnets is done by mixing the magnetic powder of NdFeB product jet mill with a non-magnetic binder (epoxy resin). Comparison of variation of NdFeB magnetic powder composition with a binder (%wt) 97:3, 95:5, 92:8 of total mass 5 grams. After mixing the powder, then compacted with a hydraulic press, using a 1.8 cm diameter mold with a force of 5 tons, with a compaction time of 5 minutes. The pellet samples were characterized by physical and magnetic properties. Characterization of physical properties includes measurement of density, mechanical properties and corrosion resistance. Characterization of magnetic properties includes measurements of magnetic field strength and magnetic properties characteristics. Measurement of magnetic field strength using Gaussmeter and measurement of characteristic magnetic properties using VSM (Vibrating Sample Magnetometer). The results showed that the optimum physical properties density is the sample with the addition of 3 %wt epoxy resin (density of 5.285 g/cm3) and optimum physical properties compressive strength is the sample with the addition of 8 %wt epoxy resin (compressive strength 10 kgF/cm2) and optimum physical resistance corrosion is the sample with the addition of 3 %wt epoxy resin (with mass change 5,48 gram with time immersion 504 hours). And for the optimum magnetic properties obtained in the test sample with the addition of an epoxy resin binder composition of 3 %wt (magnetic field strength 1029.02 Gauss, remanence 62.21 emu/gram, coercivity 9457 Oe and saturation 101 emu/gram).