bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing celery’s growth, production, quality, and nutritional status using tryptophan and glycine amino acids
Authors: El-Tanahy A. M. M. , Mahmoud Sami H. , Elwahed Mohamed S. A. Abd , Salama Dina M. 
Published: November 2024

AbstractFinding a way to establish a sustainable cultivation system to produce celery as an important source of human being nutrition system due to its health and nutritional advantages is increasing by the day. Amino acids have a deep impact on plant metabolism; they improve mineral uptake and increase shoots and root growth, yield, chlorophyll biosynthesis, and photosynthesis rate as well as encouraging stimulation of several enzymes and coenzymes which lead to improved plant development and production besides quality. A two-year (2021/2022–2022/2023), trial was conducted to discuss two essential amino acids Glycine (GLY) and Tryptophan (TRP) effect on celery’s growth, production, photosynthetic pigments, vitamin (C), total phenols, total flavonoids, total antioxidant activity, total indoles, nutritional status, and amino acids contents. During the winter season, three levels of each amino acid (0, 50, and 75 mg/l) were sprayed in two doses after 30 days of cultivation and 15 days from the first foliar. Results showed that the best performance of amino acids on plants vegetative growth characteristics, photosynthetic pigments, biochemical constituents, yield, and amino acids content was conducted by using (GLY + TRP) mix followed by TRP then GLY, while the best level of foliar applied amino acids was 75 mg/l in concentration. The best results on celery’s vegetative growth, yield, chemical content, and amino acid content were recorded by using the (GLY + TRP) mix at the highest level of 75 mg/l in concentration.
Inter- and intra-examiner reliability of short-term measurement of heart rate variability on rest in patients hospitalized with COVID-19
Authors: Santos-de-Araújo Aldair Darlan , Oliveira Murilo Rezende , Pontes-Silva André , Rodrigues Laise Nunes , Costa Cyrene Piazera Silva , Marinho Renan Shida , de Sousa dos Santos Sigrid , Arena Ross , Phillips Shane A. , Bassi-Dibai Daniela , Borghi-Silva Audrey 
Published: November 2024

AbstractMeasures reflecting cardiac sympathovagal activity, particularly those associated with heart rate variability (HRV), are widely recognized and utilized in both scientific and clinical contexts. This study aimed to assess the inter- and intra-examiner reliability of short-term HRV parameters in patients hospitalized with coronavirus disease 2019 (COVID-19). A total of 103 patients (both sexes) diagnosed with COVID-19 were included in the study. HRV was analyzed using both linear and nonlinear methods. Reliability was evaluated through intraclass correlation coefficient (ICC2.1), minimum detectable change (MDC), standard error of measurement (SEM), and coefficient of variation (CV). According to Fleiss’ criteria, excellent reliability was demonstrated, with ICC values ranging from 0.970 to 0.999 for Examiner 1, and from 0.956 to 0.999, for Examiner 2. In the inter-examiner analysis, the ICCs of HRV parameters ranged from 0.972 to 0.999. SEM values for intra-examiner reliability for Examiner 1 ranged from 0.02 to 5.64, with MDC values from 0.05 to 15.64, and CV (%) from 0.28 to 8.04. For Examiner 2, SEM values ranged from 0.02 to 8.18, MDC values from 0.05 to 22.68, and CV (%) from 0.24 to 8.14. For inter-examiner reliability, SEM values ranged from 0.02 to 6.17, MDC from 0.06 to 17.11, and CV (%) from 0.34 to 9.81. Across all analyses, CVs for HRV parameters remained below 10%. Considering different time points and different examiners, short-term resting HRV measurements in patients hospitalized with COVID-19, as evaluated using a portable heart rate device, exhibit high reliability.
High-throughput Bronchus-on-a-Chip system for modeling the human bronchus
Authors: Mori Akina , Vermeer Marjolein , van den Broek Lenie J. , Heijmans Jeroen , Nicolas Arnaud , Bouwhuis Josse , Burton Todd , Matsumura Kazushi , Ohashi Kazuhiro , Ito Shigeaki , Kramer Bart 
Published: November 2024

AbstractAirway inflammation, a protective response in the human body, can disrupt normal organ function when chronic, as seen in chronic obstructive pulmonary disease (COPD) and asthma. Chronic bronchitis induces goblet cell hyperplasia and metaplasia, obstructing airflow. Traditional animal testing is often replaced by in vitro three-dimensional cultures of human epithelial cells to assess chronic cell responses. However, these cells are cultured horizontally, differing from the tubular structure of the human airway and failing to accurately reproduce airway stenosis. To address this, we developed the Bronchus-on-a-Chip (BoC) system. The BoC uses a novel microfluidic design in a standard laboratory plate, embedding 62 chips in one plate. Human bronchial epithelial cells were cultured against a collagen extracellular matrix for up to 35 days. Characterization included barrier integrity assays, microscopy, and histological examination. Cells successfully cultured in a tubular structure, with the apical side air-lifted. Epithelial cells differentiated into basal, ciliated, and secretory cells, mimicking human bronchial epithelium. Upon exposure to inducers of goblet cell hyperplasia and metaplasia, the BoC system showed mucus hyperproduction, replicating chronic epithelial responses. This BoC system enhances in vitro testing for bronchial inflammation, providing a more human-relevant and high-throughput method.
Histidine containing dipeptides protect epithelial and endothelial cell barriers from methylglyoxal induced injury
Authors: Wetzel Charlotte , Gallenstein Nadia , Peters Verena , Fleming Thomas , Marinovic Iva , Bodenschatz Alea , Du Zhiwei , Küper Katharina , Dallanoce Clelia , Aldini Giancarlo , Schmoch Thomas , Brenner Thorsten , Weigand Markus Alexander , Zarogiannis Sotirios G. , Schmitt Claus Peter , Bartosova Maria 
Published: November 2024

AbstractIntegrity of epithelial and endothelial cell barriers is of critical importance for health, barrier disruption is a hallmark of numerous diseases, of which many are driven by carbonyl stressors such as methylglyoxal (MG). Carnosine and anserine exert some MG-quenching activity, but the impact of these and of other histidine containing dipeptides on cell barrier integrity has not been explored in detail. In human proximal tubular (HK-2) and umbilical vein endothelial (HUVEC) cells, exposure to 200 µM MG decreased transepithelial resistance (TER), i.e. increased ionic permeability and permeability for 4-, 10- and 70-kDa dextran, membrane zonula occludens (ZO-1) abundance was reduced, methylglyoxal 5-hydro-5-methylimidazolones (MG-H1) formation was increased. Carnosine, balenine (ß-ala-1methyl-histidine) and anserine (ß-ala-3-methyl-histidine) ameliorated MG-induced reduction of TER in both cell types. Incubation with histidine, 1-/3-methylhistidine, but not with ß-alanine alone, restored TER, although to a lower extent than the corresponding dipeptides. Carnosine and anserine normalized transport and membrane ZO-1 abundance. Aminoguanidine, a well-described MG-quencher, did not mitigate MG-induced loss of TER. Our results show that the effects of the dipeptides on epithelial and endothelial resistance and junction function depend on the methylation status of histidine and are not exclusively explained by their quenching activity.
Allometric fat mass index and alanine aminotransferase attenuate the associations of platelet parameters with lung cancer risk
Authors: Christakoudi Sofia , Tsilidis Konstantinos K. , Gunter Marc J. , Riboli Elio 
Published: November 2024

AbstractWe have previously shown that body mass index attenuates a positive association of platelet count (PLT) and inverse of mean platelet volume (MPV) with lung cancer risk in men. It is unclear whether fat mass, lean mass, or liver function tests (LFTs) show similar attenuations. Using bioelectrical impedance measurements (UK Biobank cohort) and multivariable Cox proportional hazards models, we examined the associations of allometric fat-mass index (AFI, fat mass adjusted for height), allometric lean-mass index (ALI, fat-free mass adjusted for height and fat mass), and LFTs with lung cancer risk and their multiplicative and additive interactions with platelet parameters. Based on 1573 lung cancer cases in men and 1473 in women with body composition measurements (1541 in men; 1428 in women with biomarker measurements), AFI in women, ALI in both sexes, alanine aminotransferase (ALT) and total bilirubin in men were inversely associated, while gamma-glutamyl transferase in men and alkaline phosphatase in both sexes were positively associated with lung cancer risk. Only AFI and ALT interacted inversely with PLT and positively with MPV in men. The attenuation of the associations of platelet parameters with lung cancer risk by high-AFI and high-ALT in men suggests that adiposity-related factors hinder lung-cancer-related platelet associations.
Continuous versus Intermittent Blood Pressure Monitoring in Postpartum Preeclampsia with Severe Features
Authors: Woolcock Martinez Helen , Haghighi Noora , van Wingerden Anne-Sophie , Kirschner Michael , Booker Whitney A. , Bello Natalie A. , Petersen Nils , Miller Eliza C. 
Published: November 2024

Objective In this study, we piloted the use of continuous 24-hour blood pressure (BP) monitoring in postpartum patients with preeclampsia with severe features.
Study Design We measured continuous BP for up to 24 hours using finger plethysmography. We also used an oscillometric device to measure brachial BP per usual clinical protocol (intermittent BP) during the same monitoring period. Using a paired t-test, we compared mean BP values assessed using intermittent and continuous methods, and using McNemar's test, we compared the proportion of patients with sustained severe-range BP using each BP measurement method.
Results A total of 25 patients were included in this study. There was no difference in mean systolic BP (SBP) and mean arterial pressure between intermittent and continuous BP measurements. Intermittently recorded mean diastolic BP (DBP) was significantly higher than continuously recorded DBP. Eleven participants (44%) had sustained SBP ≥160 mm Hg using continuous monitoring compared with two using intermittent monitoring (p = 0.003). Of these 11 participants, 3 (37%) also recorded sustained DBP ≥110 mm Hg using continuous monitoring compared with none using intermittent monitoring.
Conclusion Continuous BP monitoring is a feasible and reliable method for detecting sustained severe-range BP in postpartum patients receiving treatment for preeclampsia with severe features.
Key Points
GALADRIEL: A facility for advancing engineering science relevant to rep-rated high energy density physics and inertial fusion energy experiments
Authors: Collins G. W. , McGuffey C. , Jaris M. , Vollmer D. , Dautt-Silva A. , Linsenmayer E. , Keller A. , Ramirez J. C. , Sammuli B. , Margo M. , Manuel M. J.-E. 
Published: November 2024

Many current and upcoming laser facilities used to study high-energy-density (HED) physics and inertial fusion energy (IFE) support operating at high rep-rates (HRRs) of ∼0.1–10 Hz, yet many diagnostics, target-fielding strategies, and data storage methods cannot support this pace of operation. Therefore, established experimental paradigms must change for the community to progress toward rep-rated operation. To this end, we introduce the General Atomics LAboratory for Developing Rep-rated Instrumentation and Experiments with Lasers, or GALADRIEL, to serve as a test bed for developing and benchmarking the engineering science advancements required for HRR experiments. GALADRIEL was constructed from the ground up around a commercial 1 TW (∼25 mJ in ∼25 fs at 800 nm) laser with diverse experimental applications in mind. Assembly of the basic framework of GALADRIEL concluded with commissioning shots generating ∼1–4 MeV electrons via laser-wakefield acceleration (LWFA) using a nitrogen gas jet. Subsequent LWFA experiments operated at 1 Hz, utilized instrument feedback for optimization, and stored all data in a custom-built NoSQL database system. From this database called MORIA, or the MOngodb Repository for Information Archiving, data are retrievable via individual files or en masse by query requests defined by the user. GALADRIEL focuses on outstanding questions in engineering science, including targetry, diagnostics, data handling, environmental and materials studies, analysis and machine learning algorithm development, and feedback control systems. GALADRIEL fills a niche presently missing in the US-based user-facility community by providing a flexible experimental platform to address problems in engineering science relevant to rep-rated HED and IFE experiments.
Comparing parameterized and self-consistent approaches to ab initio cavity quantum electrodynamics for electronic strong coupling
Authors: Manderna Ruby , Vu Nam , Foley Jonathan J. 
Published: November 2024

Molecules under strong or ultra-strong light–matter coupling present an intriguing route to modify chemical structure, properties, and reactivity. A rigorous theoretical treatment of such systems requires handling matter and photon degrees of freedom on an equal quantum mechanical footing. In the regime of molecular electronic strong or ultra-strong coupling to one or a few molecules, it is desirable to treat the molecular electronic degrees of freedom using the tools of ab initio quantum chemistry, yielding an approach referred to as ab initio cavity quantum electrodynamics (ai-QED), where the photon degrees of freedom are treated at the level of cavity QED. We analyze two complementary approaches to ai-QED: (1) a parameterized ai-QED, a two-step approach where the matter degrees of freedom are computed using existing electronic structure theories, enabling the construction of rigorous ai-QED Hamiltonians in a basis of many-electron eigenstates, and (2) self-consistent ai-QED, a one-step approach where electronic structure methods are generalized to include coupling between electronic and photon degrees of freedom. Although these approaches are equivalent in their exact limits, we identify a disparity between the projection of the two-body dipole self-energy operator that appears in the parameterized approach and its exact counterpart in the self-consistent approach. We provide a theoretical argument that this disparity resolves only under the limit of a complete orbital basis and a complete many-electron basis for the projection. We present numerical results highlighting this disparity and its resolution in a particularly simple molecular system of helium hydride cation, where it is possible to approach these two complete basis limits simultaneously. In this same helium hydride system, we examine and compare the practical issue of the computational cost required to converge each approach toward the complete orbital and many-electron bases limit. Finally, we assess the aspect of photonic convergence for polar and charged species, finding comparable behavior between parameterized and self-consistent approaches.
Multi-hop quantum teleportation based on HSES via GHZ-like states
Authors: Jiang 蒋 She-Xiang 社想 , Wei 韦 Xiao-Long 晓龙 , Li 李 Jin-Huan 金欢 , Li 李 Shuai-Shuai 帅帅 
Published: November 2024

Abstract
Implementing quantum wireless multi-hop network communication is essential to improve the global quantum network system. In this paper, we employ eight-level GHZ states as quantum channels to realize multi-hop quantum communication, and utilize the logical relationship between the measurements of each node to derive the unitary operation performed by the end node. The hierarchical simultaneous entanglement switching (HSES) method is adopted, resulting in a significant reduction in the consumption of classical information compared to multi-hop quantum teleportation (QT) based on general simultaneous entanglement switching (SES). In addition, the proposed protocol is simulated on the IBM Quantum Experiment platform (IBM QE). Then, the data obtained from the experiment are analyzed using quantum state tomography, which verifies the protocol’s good fidelity and accuracy. Finally, by calculating fidelity, we analyze the impact of four different types of noise (phase-damping, amplitude-damping, phase-flip and bit-flip) in this protocol.
Correcting on-chip distortion of control pulses with silicon spin qubits
Authors: Ni 倪 Ming 铭 , Ma 马 Rong-Long 荣龙 , Kong 孔 Zhen-Zhen 真真 , Chu 楚 Ning 凝 , Liao 廖 Wei-Zhu 伟筑 , Zhu 祝 Sheng-Kai 圣凯 , Wang 王 Chu 儲 , Luo 罗 Gang 刚 , Liu 刘 Di 頔 , Cao 曹 Gang 刚 , Wang 王 Gui-Lei 桂磊 , Li 李 Hai-Ou 海欧 , Guo 郭 Guo-Ping 国平 
Published: November 2024

Abstract
In semiconductor quantum dot systems, pulse distortion is a significant source of coherent errors, which impedes qubit characterization and control. Here, we demonstrate two calibration methods using a two-qubit system as the detector to correct distortion and calibrate the transfer function of the control line. Both methods are straightforward to implement, robust against noise, and applicable to a wide range of qubit types. The two methods differ in correction accuracy and complexity. The first, coarse predistortion (CPD) method, partially mitigates distortion. The second, all predistortion (APD) method, measures the transfer function and significantly enhances exchange oscillation uniformity. Both methods use exchange oscillation homogeneity as the metric and are suitable for any qubit driven by a diabatic pulse. We believe these methods will enhance qubit characterization accuracy and operation quality in future applications.
Effect of orbital symmetry on atomic ionization in near-infrared laser fields
Authors: Xu 徐 Manqi 嫚琦 , Hu 胡 Shilin 师林 , Guo 郭 Li 丽 , Chen 陈 Jing 京 
Published: November 2024

Abstract
We have performed a comparative study of the photoelectron spectra adopting different initial states (2s or 2p0) of hydrogen atoms in a near-infrared laser pulse by using the full three-dimensional time-dependent Schrödinger equation. It is demonstrated that the atomic photoelectron spectra oscillate out of step as a function of electron kinetic energies for different initial states (2s or 2p0), which is well reproduced by the simulations based on strong field approximation, and the above distinct feature is ascribed to the different interferences from the partial electron wave packets detached by positive and negative electric fields for different initial states of 2s and 2p0.
Novel Retrofitting Technique for Beam by External Wrapped with Glass Fiber and Internally Embedded Damper System for Sustainable Construction
Authors: Kallur Gourish , Roopa A.K , Hunashyal A. M. , Hiremath Murughendra 
Published: November 2024

Abstract
Reinforced concrete structures are often exposed to extreme loads, such as those from sudden and accidental impacts. This has led to an increasing interest in strengthening these structures, improving their fatigue performance, and extending their service life, particularly for components like beams. A more sustainable approach to maintaining their functionality involves strengthening and repairing damaged components. Therefore, glass fiber polymers are ideal reinforcements for retrofitting due to their high tensile strength and low cost compared to other polymer substitutes This paper presents the performance of plain concrete beams reinforced externally with glass fiber sheets (GFS) and dampers embedded internally. A unique methodology has been adopted to improve the adhesion between the fiber glass sheets (GFS) and the concrete surface. Two adhesive components utilized are epoxy resin (ER) and epoxy hardener (EH), mixed in a ratio of 9:1. Internally embedded dampers are devices used to resist lateral forces on structures, particularly during impact or sudden loading. The adopted damper technique involves incorporating chopped Glass Fiber during the casting process of the dampers. These dampers are subsequently embedded into beams at point of failure. After the curing of 28 days, all the cast beam compositions undergo flexural test, and dampers are tested for compressive strength. After the dampers have undergone compression testing, a microstructural analysis is conducted using SEM (Scanning Electron Microscope). For further details on stress formation in beams, finite element analysis of Ansys is used to model beams for all beam compositions. Also, sustainability goals are addressed by reducing cement usage in construction by introducing retrofitting in older buildings and using this system to improve the design of newer buildings by reducing overall section sizes
A Study on γ-Ray Attenuation in MnO
Authors: Madhusudhan Rao A S , Kalyani Parcha , Shankar J 
Published: November 2024

Abstract
An experimental study has been conducted to determine the attenuation of γ-photons in Manganese oxide (MnO). Determining the thermophysical properties of the chemical at various temperatures within the 300K–1075K temperature range is the primary goal of the study. Additionally, the investigation on attenuation has been expanded to assess photon interaction characteristics at varying γ-energies.
Hot Ductility Behaviour of AA7075-T651 Aluminium Alloy
Authors: Karthikeyan KMB. , Cyril Moses L , Eshwar NK , Sam Richard N , Sai Ram B 
Published: November 2024

Abstract
This study focused on examining the hot ductility characteristics of aluminium alloy 7075-T651. Hot ductility is the capacity of a substance to undergo deformation at high temperatures without fracturing. Aluminium alloys typically demonstrate favorable hot ductility, rendering them appropriate for a wide range of high-temperature applications. The investigation entails performing hot tensile tests for AA7075-T651 aluminium alloy at different deformation temperatures (350°C-525°C), followed by fractography to ascertain the fracture mode. The ductility of the AA7075-T651 alloy was greatly enhanced during this procedure. The findings indicate that the hot working range of the aluminium alloy 7075-T651 can be expanded to 525°C instead of a liquidus start temperature of 477°C with a maximum of 30% ductility. The fractography results demonstrate that the fracture mode remains ductile. The AA7075-T651 aluminium alloy exhibits excellent thermal stability, allowing it to be hot worked at temperatures as high as 525°C without experiencing any sudden alterations in its characteristics or fracture behaviour.