bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of major complication and survival rates between surgical ligation and use of a canine ductal occluder device for treatment of dogs with left-to-right shunting patent ductus arteriosus
Authors: Ranganathan Bharadhwaj , LeBlanc Nicole L. , Scollan Katherine F. , Townsend Katy L. , Agarwal Deepmala , Milovancev Milan 
Published: October 2018

Abstract
OBJECTIVE To compare rates of major intraoperative complications and survival to hospital discharge between surgical ligation (SL) and canine ductal occluder (CDO) implantation for treatment of dogs with left-to-right shunting patent ductus arteriosus (PDA).
DESIGN Retrospective cohort study.
ANIMALS 120 client-owned dogs with left-to-right shunting PDA (62 treated by SL and 58 treated by CDO implantation).
PROCEDURES Data were retrieved from medical records of included dogs regarding signalment, medical history, vertebral heart scale, preoperative echocardiographic findings, complications encountered during surgery, and durations of anesthesia and surgery (SL or CDO implantation). Data were compared between dogs treated by SL and those treated by CDO implantation.
RESULTS Dogs treated by CDO implantation were significantly older and heavier than dogs treated by SL and had more pathological cardiac remodeling (as indicated by mitral regurgitation scores, left atrial-to-aortic root diameter ratios, and fractional shortening values). Durations of anesthesia and surgery were also significantly longer for CDO implantation versus SL. The major complication rate for dogs treated by SL (6/62 [10%]) was significantly greater than that for dogs treated by CDO implantation (0/58 [0%]). One dog in the SL group died during surgery. Overall rate of survival to hospital discharge was 99% (119/120).
CONCLUSIONS AND CLINICAL RELEVANCE Both SL and CDO implantation were viable methods for PDA attenuation in the evaluated dogs. Although a greater proportion of dogs had major complications during the SL procedure, the 2 procedures had comparable rates of survival to hospital discharge.
Likelihood and outcome of esophageal perforation secondary to esophageal foreign body in dogs
Authors: Sterman Allyson A. , Mankin Kelley M. Thieman , Ham Kathleen M. , Cook Audrey K. 
Published: October 2018

Abstract
OBJECTIVE To determine the likelihood and outcome of esophageal perforation secondary to an esophageal foreign body (EFB) in dogs.
DESIGN Retrospective observational study.
ANIMALS 125 dogs evaluated for EFB at 2 veterinary teaching hospitals from January 2005 through December 2013.
PROCEDURES Data were retrieved from the medical record of each dog regarding variables hypothesized to be associated with esophageal perforation, whether esophageal perforation was present, and survival to hospital discharge. Variables were examined for associations with various outcomes.
RESULTS Bones (55/125 [44%]) and fishhooks (37/125 [30%]) were the most common types of EFBs. Fifteen (12%) dogs had an esophageal perforation (10 with a fishhook EFB and 5 with a bone EFB). No association was identified between dog body weight and esophageal perforation. Esophageal perforation was more likely in dogs with a fishhook EFB (10/37 [27%]) versus other EFBs (5/88 [6%]; OR, 6.1; 95% confidence interval, 1.9 to 9.6). Median interval from fishhook or bone ingestion to initial evaluation was significantly longer for dogs with (12 and 96 hours, respectively) versus without (1 and 24 hours, respectively) perforation. Thirteen of 15 (87%) dogs with esophageal perforation survived to hospital discharge, including all 10 dogs with perforation secondary to fishhook ingestion. Eight survivors with esophageal perforation required no surgical intervention.
CONCLUSIONS AND CLINICAL RELEVANCE Esophageal perforation was uncommon in the evaluated dogs with an EFB, and no surgical intervention was required for a large proportion of them. Fishhooks and delay between EFB ingestion and initial evaluation were risk factors for perforation.
Congenital laryngeal paralysis in Alaskan Huskies: 25 cases (2009–2014)
Authors: von Pfeil Dirsko J. F. , Zellner Eric , Fritz Michele C. , Langohr Ingeborg , Griffitts Caroline , Stanley Bryden J. 
Published: October 2018

Abstract
OBJECTIVE To characterize congenital laryngeal paralysis (CLP) in Alaskan Huskies.
DESIGN Prospective case series.
ANIMALS 25 Alaskan Huskies with CLP.
PROCEDURES Data were collected for each dog regarding signalment; history; results of physical, orthopedic, neurologic, and laryngeal examinations; esophagraphic findings; treatments; histologic findings; and outcomes.
RESULTS Severely affected dogs were profoundly dyspneic at birth or collapsed after brief exercise; less affected dogs reportedly tired easily or overheated with minimal exercise. Mean age at initial onset of clinical signs was 6.4 months. Blue eyes, white facial markings, and oral mucosal tags or tissue bands were noted in 23 (92%), 19 (76%), and 13 (52%) dogs. Neurologic examination revealed signs of mononeuropathy of the recurrent laryngeal nerve but not of polyneuropathy. Histologic examination revealed neurogenic atrophy of the cricoarytenoideus dorsalis muscle but no polyneuropathy. Eight (32%) dogs underwent unilateral cricoarytenoid lateralization, resulting in substantial clinical improvement, including ability to compete in sled dog races. Without surgery, 4 (16%) dogs died of asphyxiation, 10 (40%) had spontaneous improvement of clinical signs (but insufficient improvement to race), and 3 (12%) remained affected. Results of pedigree analysis suggested an autosomal recessive mode of CLP inheritance, with variable penetrance.
CONCLUSIONS AND CLINICAL RELEVANCE CLP in the evaluated Alaskan Huskies involved mononeuropathy of the recurrent laryngeal nerves, without polyneuropathy. Most affected dogs had blue eyes, white facial markings, and oral mucosal tags or tissue bands. Given the apparent genetic component to CLP in this breed, we recommend that dogs with these features be prevented from breeding.
Newsletter Fall 2018: Clinician Investigator Trainee Association of Canada (CITAC)
Authors: Barton Kristen I , Ma Xiya , Pietrobon Adam , Capozzi Lauren C , Joshua Abraham Karan 
Published: October 2018

Message from the President: Optimism for the Future
The Clinician-Investigator Trainee Association of Canada (CITAC) was established in 2006 to address issues relevant to Canadian trainees seeking dual training in medicine and research. As clinician-investigator (CI) trainees, we comprise but a fraction (less than 5%) of all medical trainees. Our ‘bilingual’ careers render our individual paths less straightforward and more challenging. As a community, we have had to confront several disappointments, perhaps most notably the cessation of funding support for MD/PhD programs in 2015, previously offered by the Canadian Institutes of Health Research (CIHR). Despite these individual and collective challenges, I remain optimistic and incredibly excited about our future. In my own work, I am reminded constantly that being trusted with the dual responsibility of patient care and innovation in medicine is a privilege to be cherished, rather than a burden to be feared. That which makes our path doubly challenging also makes it doubly rewarding. The progress that CITAC has made over the years only adds to my optimism, and I wish to take this opportunity to remind you of how far we have come and how much further we hope to go.
Spontaneous Osteonecrosis of the Knee
Authors: Bittner Justin , Hartstein Aaron 
Published: October 2018

A 69-year-old man was referred to physical therapy by his primary care physician for an insidious onset of right medial knee pain that had been present for over 4 weeks. Due to the disproportionate response following initial management, he was referred to an orthopaedist for imaging. Magnetic resonance imaging revealed medial femoral condyle osteopenia, bone marrow edema, and subchondral bone collapse, and subsequently the patient was diagnosed with spontaneous osteonecrosis of the knee. J Orthop Sports Phys Ther 2018;48(10):824. doi:10.2519/jospt.2018.7923
TÜRKİYE’DE CARİ AÇIK MAKASI DARALTILABİLİR Mİ?
Authors: KEKEÇ H. Muhammet , KUZU Serdar 
Published: October 2018

Türkiye’nin
ekonomik alanda önemli sorunlarından birisi cari açık problemidir. Söz konusu
problem Türkiye’nin dönem dönem ekonomik krizlerle karşılaşmasında rol
oynamakla birlikte ekonomik anlamda hareket alanını kısıtlamaktadır. Bu anlamda
Türkiye’nin istikrarlı büyüme ve ekonomik krizlerle karşılaşma riskinin aza
indirilmesi için, cari açık makasının daraltılmasıyla birlikte buna kalıcı çözümler
getirilmesi gerekmektedir. Cari açığın
nedenleri arasında üretim ve tüketim faaliyetlerinin dışa bağımlılığı ile
birlikte döviz kurundaki dalgalanmalar, üretimin temel kaynağı olan enerji
maliyetlerinin yüksekliği, iç ve dış talepteki yüksek değişiklikler gibi
konjonktüre bağlı dalgalanmalar olarak saymak mümkündür. Bu bağlamda ülke
ekonomisinin üretim, tüketim ve tasarruf yapısı cari açık makasında etkili
olmaktadır. Söz konusu etki neticesinde cari açık makasını daraltmaya yönelik
üretimde, tüketimde ve tasarruf alanlarında yapısal tedbirler gerektirmektedir.

Cari
açık makası üretim sektörünün ithalata bağlı üretim politikası ile de yakından
ilgilidir. İhracata konu olan ürünlerin üretiminde ithal ürünler yerine ulusal
ürünlerin kullanımı da bu makasın daralmasında önemli bir etkiye sahip
olacaktır. Bir diğer önemli yapısal sorun ise enerji kaynaklarının üretim
faaliyetlerinde kullanımının fazla olması ve bu kaynakların temininde de dışa
bağlı olunmasıdır. Enerji alanında nükleer enerji gibi yeni teknolojilerin
kullanımı ile birlikte bu alanda da dışa bağımlılığın azalması ve üretim
kanallarında kullanıma geçirilmesi ile birlikte cari açık makası aleyhine olan
durumun terse çevrilme imkânının yakalanması beklenmektedir. Cari açık
makasının daraltılmasında etkili olan faktörlerin tespiti ile bu açığı
kapatmaya yönelik çözüm yolları ortaya konulmalıdır. Bu çalışmada, cari açık
makasının daraltılmasına yönelik çözüm yolları tartışılacaktır.
Update in management of hepatitis B in pregnancy and prevention of mother to child hepatitis B transmission
Authors: Chamroonkul Naichaya 
Published: October 2018

Even with two decades of widespread using hepatitis B vaccination, chronic hepatitis B remains a major global health problem. In Thailand, the prevalence of chronic hepatitis B infection was down from 8 - 10% in last decade to 5% recently. Failure to control mother to child transmission is one of the important barriers to the total elimination of hepatitis B infection from world population. In the majority, vertical transmission can be prevented with a universal screening program, immunoprophylaxis by administration of hepatitis B vaccine and hepatitis B immunoglobulin (HBIg) for babies born to mothers with HBV. However, in mothers with a high viral load, the chance of immunoprophylaxis failure remains high. To date, there are standard recommendations by all international liver societies including AASLD, EASL and APASL suggest introducing an antiviral agent during the third trimester to CHB pregnant women with a high viral load. Previous US FDA pregnancy category B agents such as Tenofovir and Telbivudine are allowed through all trimesters of pregnancy and are effective for prevention of mother to child transmission. Breastfeeding for patients who receive antiviral agents can be allowed after a risk-benefit discussion with the patient and family.
Analisis Perbandingan Kepuasan Pasien terhadap Pelayanan Kebidanan pada Peserta BPJS (Badan Penyelenggara Jaminan Sosial) dan non BPJS di Ruang Bersalin RSUD Soegiri Lamongan Jawa Timur
Authors: Darwati Lilik 
Published: October 2018

Latar Belakang: Setiap pasien selalu mengharapkan pelayanan yang berkualitas sehingga dapat tercapai kepuasan. Oleh karenanya setiap unit pelayanan kesehatan harus memberikan pelayanan yang sama kepada setiap pasien baik sebagai pasien BPJS maupun non BPJS. Tujuan: Mengetahui perbedaan tingkat kepuasan pasien terhadap pelayanan kebidanan pada pasien BPJS dan Non BPJS di Ruang Nifas Kelas II RSUD Soegiri lamongan. Metode: Desain penelitian yang digunakan adalah observasional analitik yang dilakukan dengan metode cross sectional. Populasi adalah populasi terhingga (finite population) yaitu ukuran populasi yang besarnya masih bisa dihitung (cauntable) dengan sample 70 responden diambil dengan teknik purposive sampling. Variabel bebas adalah jenis kepesertaan pasien BPJS dan non BPJS terikatnya kepuasan terhadap pelayanan kebidanan. Data dikumpulkan menggunakan kuesioner dan dianalisis dengan uji Mann Whitney.
The Response of Some Properties of (Al-Si-Mg) Alloy to Nano-Ceramic Materials’ Addition
Authors: Ibrahim Sarmad Imad , Tawfeeq Arwa Faraj 
Published: October 2018

Al-Si alloys which are widely used in engineering applications due to their outstanding properties can be modified for more enhancements in their properties. Current work investigated the ability of these alloys to be modified by casting them through the addition of nanoparticles. So, Multi-wall carbon nanotubes (CNT) and titanium carbide ceramic particles (TIC) with size of (20 nm) were added with different amounts started from (0.5 up to 3%) weight to cast alloy A356 that was considered to be the base metal matrix, then stirred with different speeds of (270, 800, 1500, 2150) rpm at 520 °C for one minute. The results showed change in microstructure’ shape of the casted alloys from the dendritic to spherical grains with increasing stirring speed. Also, EDX analysis confirmed the existence of CNT and TIC additions over inter-dendritic locations related to the affected area. However, the enhancement in the mechanical properties for both types of castings was gained at a weight of 2.5% and a stirring speed of 1500 rpm.
Effect of Various Substrates on Growth and Yield Performance of Oyster Mushroom (Pleurotus ostreatus) in Chitwan, Nepal
Authors: Sitaula Hom Prasad , Dhakal Roshan , DC Geetesh , Kalauni Dharmendra 
Published: October 2018

An experiment was conducted at Rampur, Chitwan, Nepal to find out the growth and yield performance of oyster mushroom (Pleurotus ostreatus) in Completely Randomized Design (CRD).The treatment includes the four different substrate i.e. paddy straw (100%), maize cob+ paddy straw (1:1), sugarcane bagasses+paddy straw (1:1) and sawdust+ paddy straw (1:1). The parameters taken for the observation during the experiment were colonization period, fruit initiation period, length of stalk, diameter of stalk, diameter of pileus, fresh weight of the first and second flush of mushroom and also the biological efficiency (BE) of various substrates. Among the used substrates, the time for colonization and fruit initiation was found to be shorter in case of the paddy straw i.e.18.25 days and 21.75 days respectively. However, the length of stalk was highest in sugarcane bagasses+paddy straw (1:1) i.e.6.10 cm, but the diameter of stalk and pileus were highest in paddy straw i.e.0.80 cm and 7.90 cm respectively. Similarly, the biological efficiency was found to be highest in case of the paddy straw (96.29688%) followed by maize cob+paddy straw (1:1), sugarcane bagasses+ paddy straw (1:1) and sawdust+ paddy straw (1:1) respectively.Int. J. Appl. Sci. Biotechnol. Vol 6(3): 215-219
Intrathecal Magnesium Sulfate as Analgesic and Anaesthetic Adjunct to Bupivacaine in Patients Undergoing Lower Extremity Orthopaedic Surgery
Authors: Limbu Prakash Maden , Khatiwada Sindhu , Sah Birendra Prasad , Singh Satyendra Narayan , Pokharel Krishna , Maharjan Rajiv 
Published: October 2018

Background: Subarachnoid block is a popular mode of anesthesia for lower limb surgeries. Studies of Magnesium Sulfate (MgS04 ) as an adjuvant to intrathecal local anaesthetic are limited. The objective was to find out the analgesic and anaesthetic effect of intrathecal MgS04 added to bupivacaine for spinal anaesthesia in patients undergoing lower extremity orthopaedic surgery.Methods: Sixty ASA I or II adult patients undergoing lower extremity orthopaedic surgery were randomly allocated in a double blinded fashion into two groups of thirty each. Group A received 3.0 ml of 0.5% hyperbaric bupivacaine with 0.15 ml of 50% MgSO4. Group B received 3.0 ml of 0.5% hyperbaric bupivacaine with 0.15 ml of NS. Onset of sensory and motor block as well as time to attain highest level of sensory block were recorded. Duration of sensory and motor block along with duration of spinal anaesthesia were also assessed. Any adverse effects were noted and treated.Results: Duration of sensory and motor block along with duration of spinal anaesthesia were prolonged in patients of MgSO4 but were not statistically significant with p-value of 0.33, 0.23 and 0.68 respectively. Onset of anaesthesia, requirement of rescue analgesics, haemodynamic parameters and adverse effects were comparable between two groups.Conclusion: In patients undergoing lower extremity orthopaedic surgery the addition of 75mg of MgSO4 to intrathecal bupivacaine did not prolong the duration of sensory block, spinal anaesthesia nor decreased postoperative analgesic consumption without any additional side effects. Journal of Society of Anesthesiologists of NepalVol. 4, No. 2, 2017, Page: 74-80
Awake resection of a left operculo-insular low-grade glioma guided by cortico-subcortical mapping
Authors: Picart Thiébaud , Duffau Hugues 
Published: October 2018

A 30-year-old right-handed female medical doctor experienced generalized seizures. MRI showed a left operculo-insular low-grade glioma. Awake resection was proposed. During the cortical mapping, counting and naming task combined with right upper limb movement enabled the identification of the ventral premotor cortex and negative motors areas. The so-called Broca’s area was not eloquent. Subpial dissection was performed by avoiding coagulation until the inferior fronto-occipital fasciculus and the junction between the output projection fibers and the anterior part of the superior longitudinal fasciculus III were reached. The patient resumed a normal familial and socio-professional life despite the resection of Broca’s area.The video can be found here: https://youtu.be/OALk0tvctQw.
Intraoperative awake brain mapping and multimodal image-guided resection of dominant side insular glioma
Authors: Yu Zhengda , Hameed N. U. Farrukh , Zhang Nan , Wu Bin , Zhang Jie , Lu Junfeng , Qiu Tianming , Zhuang Dongxiao , Chen Hong , Wu Jinsong 
Published: October 2018

Resection of insular tumors in the dominant hemisphere poses a significant risk of postoperative motor and language deficits. The authors present a case in which intraoperative awake mapping and multi-modal imaging was used to help preserve function while resecting a dominant insular glioma. The patient, a 55-year-old man, came to the clinic after experiencing sudden onset of numbness in the right limbs for 4 months. Preoperative MRI revealed a nonenhancing lesion in the left insular lobe. Gross-total tumor resection was achieved through the transcortical approach, and the patient recovered without language or motor deficits. Informed patient consent was obtained.The video can be found here: https://youtu.be/gFky09ekmzw.
PESANTREN DI BENTENG PROTESTAN : AKTIVITAS, RELASI DAN PERDAMAIAN
Authors: Rusli Almunauwar Bin 
Published: October 2018

A discourse about Pesantren in Protestant bastion from the New Order Era to Reform Era is significant to study for building a strong, stable, wealthy and democratic life. Pondok Karya Pembangunan Manado is Pesantren to be the focus of research. Bacause the region and the composition of interethnic and interfaith inhabitants were highly representative. This study used the qualitative-explorative type with sociological approach. The result showed that (1) There were three relation typologies including structural relation, organizational relation and cultural relations (2) There were five factors that strengthened the peace which consisted of construction of local religion, interfaith leadership system, construction of inter-offspring, curriculum centralization and santri mobilization. Thus, in summary the relations and peace activity always appeared in public spaces to develop intracommunal and intercommunal engagement.
INSTITUSI MINORITAS DAN STRUKTUR SOSIAL DI INDIA
Authors: Ruksin Raudatul Ulum 
Published: October 2018

Minoritas di India diurus di dalam satu lembaga namanya National Commision for Minoritysebagai bentuk mewujudkan perintah Undang-Undang, Act 1992. setidaknya disebutkan tiga minoritas yang secara umum dikenal di India dan diberlakukan affirmatif policy. Minoritas agama, selain penganut Hindu, penganut agama lain sebagai minoritas agama, berikutnya suku-suku rentan yang sulit mengakses kebijakan, ketiga adalah backward caste. Kasta terbelakang adalah isu sosial paling rumit di India, selain empat kasta mainstream, Brahman-Ksatryan-Vide-Sudras, terdapat kasta kelima yang sejatinya belum diakui. Mereka dinamakan dengan Dalit, secara sosial menempati kelas terbawah dalam kultur India. Relasi sosial yang unik terjadi antara penganut Hindu yang berkasta rendah, dengan institusi muslim cukup unik, kebijakan Aligarh Muslim University yang memberikan beasiswa masyarakat miskin dan rentan cukup memberikan arti terhadap perubahan. Meksipun sistim sosial India secara umum memengaruhi masyarakat Islam yang secara ajaran mengajarkan norma tanpa kasta, namun dalam kenyataannya muncul istilah asraf, asykal dan ajlaf. Asraf adalah level sosial tersendiri ditarik secara politik dan sejarah merupakan keturunan aristokrat dan rohaniwan Islam. biasanya identifikasi pada khan dan syed. Kolonialisme Inggris semakin memertegas demarkasi level sosial melalui East Indian British, mereka kepala pasukan Inggris yang berasal dari India diberi gelar Sir, melengkapi seperangkat identitas Syed di depan nama, kemudian Khan di belakang nama. Kemudian posisi Asykal adalah level sosial konversi wangsa Sudra, sedangkan Ajlaf adalah mereka yang hidup dalam level sosial manusia kebanyakan, strata sosial terbawah. Institusi minoritas adalah kelembagaan khusus untuk memberikan perlakukan khusus pada kelompok agama agar nantinya berada dalam kondisi yang sama dengan kebijakan secara umum. Konflik antaragama juga bagian dari isu penting untuk menggambarkan keadaan masyarakat dan kebijakan di India. Muslim umumnya menganggap Hinduisme adalah wajah kultural di India, sampai pada perspektif membaca data sensuspun mereka meyakini jumlahnya bisa lebih besar dari yang disebutkan. Belum lagi menyangkut akses pada kebijakan dan urusan politik, muslim berjuang pada kesetaraan. Dalam hal ini pendekatan affimatif dan kesetaraan berada dalam diskusi serius sepanjang penelitian dilakukan. Penelitian ini memeroleh kesimpulan bahwa kebijakan negara menyangkut penanganan minoritas agama yang sekaligus mengurusi dua minoritas lainnya cukup baik namun tidak banyak mengubah sistem sosial yang sudah berlangsung sepanjang sejarah india.
Selective Heterogeneous Catalytic Hydrogenation of Nitriles to Primary Amines
Authors: Lévay Krisztina , Hegedűs László 
Published: October 2018

Primary amines are important intermediates, especially in the area of pharmaceutical, plastic and agrochemical industry. The heterogeneous catalytic hydrogenation of nitriles is one of the most frequently applied process for the synthesis of diverse amines. However, the control of the selectivity is a critical issue in this reaction. Over the past decade, many studies have been reported using heterogeneous transition metal catalysts for the selective reduction of nitriles to the corresponding primary amines. The type of the catalysts, especially, the chemical nature of metals in the catalysts is one of the most important factors to influence the selectivity, the reaction rate, and possibly also the reaction pathway and the deactivation of the catalyst. Thus, this review focuses on the heterogeneous transition metal catalysts and summarizes the recent developments achieved in the selective catalytic hydrogenation of nitriles to primary amines.