bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pancreatic changes in obese mice supplemented with vitamin D
Authors: da Rocha Guilherme , dos Santos Natália Pereira , Mendonça Juliana Cristina , Baptista Fassis Nathan Oscar , Calsa Bruno , Milanski Marciane , Corezola do Amaral Maria Esméria 
Published: November 2024

AbstractThis study investigates the impact of vitamin D supplementation on insulin secretion and pancreatic islet morphometry in a high-fat diet-induced obese mouse model. Male C57BL/6 mice were randomly assigned to two groups: a control group receiving a standard diet (C) and an obese group receiving a high-fat diet (H). After 12 weeks, the obese group was subdivided, with one subset continuing on the high-fat diet (H) and the other receiving vitamin D supplementation (HD) at 500 IU/kg via oral gavage for four weeks. Glucose tolerance tests, insulin sensitivity assessments, insulin secretion assays, and histological and immunohistochemical analyses for glucagon and PCNA were conducted. Vitamin D supplementation led to a reduction in fasting blood glucose levels and a significant increase in insulin secretion at 20 mM glucose, as indicated by an improved HOMA%B index, suggesting enhanced β-cell protection. Additionally, vitamin D treatment resulted in a β-cell percentage comparable to the control group and a notable increase in α-cell population relative to the untreated obese group. However, elevated circulating cholesterol levels were observed in both obese groups, with a significant rise in hepatic triglycerides in the vitamin D-treated group. These findings highlight the potential of vitamin D to improve pancreatic secretory function in obese mice.
Unlocking the power of gene banks: diversity in base growth temperature provides opportunities for climate-smart agriculture
Authors: Gambart Clara , Wesemael Jelle Van , Swennen Rony , Tardieu François , Carpentier Sebastien 
Published: November 2024

AbstractImplementation of context-specific solutions, including cultivation of varieties adapted to current and future climatic conditions, were found to be effective in establishing resilient, climate-smart agricultural systems. Gene banks play a pivotal role in this. However, a large fraction of the collections remains neither genotyped nor phenotyped. Hypothesising that significant genotypic diversity inMusatemperature responses exists, this study aimed to assess the diversity in the world’s largest banana gene bank in terms of base temperature (Tbase) and to evaluate its impact on plant performance in the East African highlands during a projected climate scenario. 116 gene bank accessions were evaluated in the BananaTainer, a tailor-made high throughput phenotyping installation. Plant growth was quantified in response to temperature and genotype-specific Tbasewere modelled. Growth response of two genotypes was validated under greenhouse conditions, and gas exchange capacity measurements were made. The model revealed genotype-specific Tbase, with 30 % of the accessions showing a Tbasebelow the reference of 14 °C. The Mutika/Lujugira subgroup, endemic to the East African highlands, appeared to display a low Tbase, although within subgroup diversity was revealed. Greenhouse validation further showed low T sensitivity/tolerance to be related to the photosynthetic capacity. This study, therefore, significantly advances the debate of within species diversity in temperature growth responses, while at the same time unlocking the power of gene banks. Moreover, we provide a high throughput method to reveal the existing genotypic diversity in temperature responses, paving the way for future research to establish climate-smart varieties.
Neural Representation of Time across Complementary Reference Frames
Authors: Xu Yangwen , Sartorato Nicola , Dutriaux Léo , Bottini Roberto 
Published: November 2024

SummaryHumans conceptualize time in terms of space, allowing flexible time construals from various perspectives. We can travel internally through a timeline to remember the past and imagine the future (i.e., mental time travel) or watch from an external standpoint to have a panoramic view of history (i.e., mental time watching). However, the neural mechanisms that support these flexible temporal construals remain unclear. To investigate this, we asked participants to learn a fictional religious ritual of 15 events. During fMRI scanning, they were guided to consider the event series from either an internal or external perspective in different tasks. Behavioral results confirmed the success of our manipulation, showing the expected symbolic distance effect in the internal-perspective task and the reverse effect in the external-perspective task. We found that the activation level in the posterior partial cortex correlated positively with sequential distance in the external-perspective task but negatively in the internal-perspective task. In contrast, the activation level in the anterior hippocampus positively correlated with sequential distance regardless of the observer’s perspectives. These results suggest that the hippocampus stores the memory of the event sequences allocentrically in a perspective-agnostic manner. Conversely, the posterior parietal cortex retrieves event sequences egocentrically from the optimal perspective for the current task context. Such complementary allocentric and egocentric representations support both the stability of memory storage and the flexibility of time construals.
RTF1 mediates epigenetic control of Th17 cell differentiation via H2B monoubiquitination
Authors: Galan Carolina , Lu Guangqing , Gill Richard , Li Dun , Liu Yifang , Huh Jun R. , Hang Saiyu 
Published: November 2024

AbstractA gene encoding the transcription factor RTF1 has been associated with an increased risk of ulcerative colitis (UC). In this study, we investigated its function in modulating T cells expressing interleukin-17A (Th17 cells), a cardinal cell type promoting intestinal inflammation. Our results indicate thatRtf1deficiency disrupts the differentiation of Th17 cells, while leaving regulatory T cells (Treg) unaffected. Mechanistically, RTF1 facilitates histone H2B monoubiquitination (H2Bub1), which requires its histone modification domain (HMD), for supporting Th17 cell function. Impaired Th17 differentiation was also observed in cells lacking the H2Bub1 E3 ligase subunit RNF40, an enzyme known to physically interact with RTF1. Thus, our study underscores the essential role of RTF1 in H2Bub1-mediated epigenetic regulation of Th17 cell differentiation. Understanding this process will likely provide valuable insights into addressing Th17-associated inflammatory disorders.Key PointsRTF1 is crucial for Th17 cell differentiation via histone H2B monoubiquitinationRTF1 deficiency impairs Th17 differentiation, similar to H2Bub1 ligase RNF40 deficiencyRTF1 and H2Bub1 colocalize on genes regulating Th17 cells, indicating an epigenetic role
Field EPSPs of dentate gyrus granule cells studied by selective optogenetic activation of hilar mossy cells in hippocampal slices
Authors: Bernstein Hannah L. , Lu Yi-Ling , Botterill Justin J. , Duffy Áine M. , LaFrancois John J. , Scharfman Helen E. 
Published: November 2024

ABSTRACTGlutamatergic dentate gyrus (DG) mossy cells (MCs) innervate the primary DG cell type, granule cells (GCs). Numerous MC synapses are on GC proximal dendrites in the inner molecular layer (IML). However, field recordings of the GC excitatory postsynaptic potential (fEPSPs) have not been used to study this pathway selectively. Here we describe methods to selectively activate MC axons in the IML using mice with Cre recombinase expressed in MCs. Slices were made after injecting adeno-associated virus (AAV) encoding channelrhodopsin (ChR2) in the DG. In these slices, we show that fEPSPs could be recorded reliably in the IML in response to optogenetic stimulation of MC axons. Furthermore, fEPSPs were widespread across the septotemporal axis. However, fEPSPs were relatively weak because they were small in amplitude and did not elicit a significant population spike in GCs. They also showed little paired pulse facilitation. We confirmed the extracellular findings with patch clamp recordings of GCs despite different recording chambers and other differences in methods. Together the results provide a simple method for studying MC activation of GCs and add to the evidence that this input is normally weak but widespread across the GC population.KEY POINTSWe describe a method to activate the MC input to GCs selectively using optogenetics in hippocampal slicesMC excitation is weakly excitatory but so common among GCs that a field EPSP is generated at the site of MC synapses on GCsMC excitation of GCs is consistent across the septotemporal axis and contralaterallyUsing the characteristics of optogenetically-evoked fEPSPs, electrical stimulation of the MC input to GCs can be optimized.
Search for the
Σ(1380)1/2−
state in
Λc+→γπ+Λ
decay by triangle singularity
Authors: Wang Ke , Wang Yu-Fei , Liu Bo-Chao , Huang Fei 
Published: November 2024

In this work, we investigate the resonance production in Λc+→γπ+Λ decay through the triangle singularity (TS) mechanism, within an effective Lagrangian approach. We find that the appropriate loop decay process could develop a triangle singularity in the invariant mass MπΛ around 1.35 GeV, with the shape depending on the quantum numbers of Σ* states that couple to the final πΛ system. Especially, the Σ(1380)1/2− state newly predicted in the pentaquark model, if exists, significantly enhances the TS contribution and sharpens the TS peak due to the S-wave Σ*πΣ vertex in the loop. Therefore, the existence of the Σ(1380)1/2− state can be examined by measuring the TS signal in Λc+→γπ+Λ. Considering also possible tree-level diagrams, we additionally obtain the branching ratio Br(Λc+→γπ+Λ)≃1.5×10−5. We suggest the investigation of this reaction by future BESIII, LHCb, and Belle experiments.

Published by the American Physical Society
2024
An analysis of the effects of aging society on global stock markets
Authors: Pankwaen Kansuda , Yamaka Woraphon , Maneejuk Paravee 
Published: November 2024

PurposeThe primary purpose of this study is to explore the effects of demographic transition toward aging populations on the performance of stock market indices across various economic developments. The research aims to provide valuable insights into the life-cycle hypothesis on savings patterns, investment behavior and the potential reverberations on global financial markets.Design/methodology/approachThe study adopts a comprehensive global perspective, scrutinizing the effects of aging populations on stock market indices across developed, developing and transitional economies through the panel data analysis. Using annual data spanning the period from 1991 to 2020, encompassing a sample of 10 countries from each economic development level, the study employs the panel autoregressive distributed lag (ARDL) model with fixed effect estimation.FindingsThe findings unveil a statistically significant positive impact of the elderly population proportion on global stock market indices. However, the magnitude and contours of this impact exhibit considerable heterogeneity across different country groups. Specifically, the study finds that while the aging population significantly influences stock market performance in developed nations, its effect is overshadowed by other economic factors, such as consumer price indices and interest rates, in developing countries and economies in transition.Originality/valueThe originality and value of this study lie in its comprehensive global perspective, which encompasses a diverse array of economies at varying developmental stages. The research contributes to an understanding of the effects of demographic transitions on stock market performance on a global scale. The insights derived from this study hold significant implications for policymakers, financial institutions and investors seeking to navigate the challenges and opportunities posed by aging societies in an increasingly interconnected global economy. Additionally, the findings highlight the need for specific strategies and policies that account for the unique economic characteristics and developmental stages of different nations.
Small green housing makes a big difference: the impact of natural environmental uncertainty on consumers' willingness to purchase green housing
Authors: Duan Zhaoping , Ding Zhihua , Mou Yupeng , Deng Xueling , Zhang Huiying 
Published: November 2024

PurposeThe residential sector is a principal contributor to global energy consumption, underscoring the critical importance of promoting green housing initiatives to mitigate energy use and environmental degradation. The prevalence of uncertainty in the natural environment, exemplified by phenomena like extreme weather events, highlights the urgent need for adaptive strategies and sustainable practices to mitigate the impact on human communities and ecosystems. Against this backdrop, this paper presents a theoretical framework examining the influence of natural environmental uncertainty on consumers' willingness to purchase green housing.Design/methodology/approachThrough three experiments, this study modeled the mechanism by which the natural environment uncertainty affects consumers' willingness to purchase green housing, and then verified the mediating effect of the threat of ontological security and the moderating effect of the degree of consumers' natural connectedness.FindingsThis paper concludes (1) natural environmental uncertainty exerts a significant positive impact on the willingness to purchase green housing, with the threat to ontological security serving as a pivotal mediating variable; (2) the degree of natural connectedness significantly moderates the effect of ontological security threats on the purchasing intent for green housing.Originality/valueThis research contributes to the marketing literature by offering a novel perspective on the impact of natural environmental uncertainty on consumer behavior, augmenting the body of knowledge concerning the determinants of green housing purchase intentions, and provides new ideas for marketers.
Analytical skills for accounting students in a data-driven job market: Australian evidence
Authors: Askary Saeed , Askarany Davood 
Published: November 2024

Purpose
The purpose of this study is to investigate the essential analytical skills required by accounting students to succeed in a rapidly evolving data-driven job market. Specifically, the study explores the role of data analytics, visualisation and software proficiency (e.g. Excel, Power BI) in the contemporary Australian accounting industry. The scope extends to providing recommendations for academia, professional bodies and employers on how accounting education can better align with the dynamic needs of the business environment by integrating these skills into curricula and professional development programmes.

Design/methodology/approach
Data was collected from Australian job listings incorporating accounting and data analytics tasks from popular job advertisement websites such as Seek, Indeed and Monster. Using the keyword “Data Analyst”, information was gathered on skills demanded, technology proficiency, industry sectors, professional qualifications and salary expectations. The data set comprised 73 observations across various job requirements and characteristics variables.

Findings
Critical analytical skills sought by accounting professionals in the current job market include extracting insights from big data, solving complex business problems, effective communication and data visualisation. Proficiency in tools like Microsoft Excel, SQL and Power BI is paramount.

Originality/value
This study enriches the literature by providing comprehensive insights into the contemporary demands for accounting analytics skills. It highlights the importance of integrating technology into accounting education and the varying skill requirements across industries. Additionally, it offers implications for professional qualifications and underscores the necessity for continuous monitoring and adaptation of accounting curricula to meet evolving industry needs.
Implementation outcomes of disaster risk reduction (DRR) policy in public facilities (PFs): Aceh perspective, Indonesia
Authors: Sufri Sofyan , Elvin Said Devi 
Published: November 2024

PurposeAceh province has established various infrastructure and regulations related to disaster risk and management after the Indian Ocean Tsunami (IOT) hit the province. Hence, this study investigates the implementation of Disaster Risk Reduction (DRR) in Public Facilities (PFs) in Banda Aceh municipality using implementation outcome variables (acceptability, adoption, appropriateness, feasibility, compliance, implementation cost, coverage and sustainability).Design/methodology/approachQualitative methods, including in-depth interviews and document reviews, were applied to collect data for this study. The data were then analysed thematically using NVivo 12 software.FindingsThe lack of public communication regarding DRR in PFs to all involved stakeholders resulted in poor acceptability, adoption, coverage and compliance with the policy implementation among public facilities’ chiefs, owners or managers. Additionally, they were reluctant to implement DRR plans and activities within their facilities due to limited DRR funds.Practical implicationsThis study’s results can contribute to reviewing the policy and practices of Aceh government authorities and other involved stakeholders to improve policy implementation of DRR activities comprehensively across eight groups of public facilities in Banda municipality, other districts in Aceh province, and local areas in Indonesia. Further, the methods used in this study to assess DRR regulations’ progress towards the eight implementation outcome variables can be applied widely to other settings.Originality/valueNo research was found on examining the policy implementation of DRR in PFs in Aceh province, which motivated the author to conduct this work.
Demographics, social norms, entrepreneurial self-efficacy and entrepreneurial intention: a social cognitive perspective on secondary students
Authors: Ho Chun Sing Maxwell , Man Thomas Wing Yan , Chiu Ming Ming 
Published: November 2024

PurposeFramed by social cognition theory, this study examines the impact of environmental factors (e.g. social norms) on students’ entrepreneurial self-efficacy (ES) and entrepreneurial intention (EI).Design/methodology/approachWe obtained responses to a survey from 811 senior secondary students in Hong Kong. We then employed structural equation modeling (SEM) to test the proposed hypothesis. We removed non-significant parameters in testing the model and obtained the final SEM.FindingsAmong these students, those who were male or spoke English at home showed stronger social norms of entrepreneurship and greater entrepreneurial SE, which was linked to greater EI. Among students perceiving stronger social norms of entrepreneurship, those who lived in private housing or spoke English at school showed greater entrepreneurial intention.Originality/valueThe study provides a new social cognitive perspective for examining EI that emphasizes learning and development through the interaction of environmental and cognitive factors. It supplements previous research by demonstrating the significant influence of social norms and the conditional role of parental influence, adding complexity to our understanding of how these factors' interplay.
Tribological properties of dual-freedom sliding roller pairs with a loss of lubrication
Authors: Zhang Wenjing , Yue Jiawei , Chen Wei , Liu Zhe , Liu Ang 
Published: November 2024

Purpose
This paper aims to design a novel test device and study the wear properties and the thermal mechanisms of roller pairs in dual-freedom sliding contacts.

Design/methodology/approach
On the transition process of lubrication regimes, experiments were conducted with various values of running speed and slip ratio obtained by two motorized spindles. Temperature and surviving time would be obtained of GCr15/GCr15 and DLC/GCr15 friction pairs. Micro photography was obtained with a PGI 3D stylus profiler and a confocal microscopy OLS4000-3D. An empirical mode decomposition method was used to eliminate measure errors.

Findings
Results showed that, even with little initial lubricant, rolling/sliding pairs still rotated for a certain time. With the synthetic actions of the dual-freedom sliding, the loss of lubrication and the tilt, interesting helical grooves appeared. Sliding speeds had remarkable effects on survive time, temperatures and surface topographies. In addition, the equilibrium values of the temperature and the surface roughness were obtained in sufficient oil supply. Extreme wear-out conditions were obtained with starved lubrication. Diamond-like carbon coatings showed better heat resistance and better wear resistance.

Originality/value
This work would be critical for the life design and the heat treatment of rolling bearings in the full flood lubrication and the starved lubrication.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-05-2024-0164/
Generalist CFO and corporate debt finance: evidence from the Chinese market
Authors: Zhou Zhiying , Xiang Ziwei 
Published: November 2024

PurposeThis study examines the relationship between chief financial officer (CFO) general ability and corporate debt financing, using all Chinese listed companies as the sample. It has significant implications for corporate shareholders and investors. Companies aiming to increase the proportion of external capital should prioritise the CFO's general ability. Similarly, investors can consider this a valuable sign before making investment decisions.Design/methodology/approachThis study follows Custódio et al.'s (2013) approach to measuring the CFO general ability index (GAI) in five dimensions, while the D/E ratio is treated as the primary proxy of corporate debt financing. This study investigates the linear relationship between CFO general ability and corporate debt financing by using the ordinary least squares (OLS) regression with controlling year and industry fixed effect simultaneously.FindingsBased on a sample dataset of all listed firms in China from 2008 to 2023, this paper identifies a significant positive correlation between CFOs' general management skills and corporate debt financing. This finding underscores that generalist CFOs prefer debt financing over equity financing. The paper also suggests that corporate innovation could be a potential mechanism through which CFOs' comprehensive management skills influence debt financing.Originality/valueThis study expands upon prior research by establishing a positive correlation between generalist CFOs and debt financing. Previous studies investigating the influence of CFO demographic characteristics have predominantly concentrated on singular dimensions, such as educational background, varied professional experiences and career trajectories, often overlooking the significance of past work experience. Secondly, this paper enriches the financial literature by introducing a novel determinant that substantially impacts debt financing.