bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formulation and characterisation of O/W emulsions stabilised with modified seaweed polysaccharides
Authors: Melanie Hakiki , Taarji Noamane , Zhao Yiguo , Khalid Nauman , Neves Marcos A. , Kobayashi Isao , Tuwo Ambo , Nakajima Mitsutoshi 
Published: July 2019

AbstractIn this study, seaweed polysaccharides (alginate and carrageenan) were modified with dodecenylsuccinic anhydride (DSA), and their stabilising properties in oil‐in‐water (O/W) emulsion system were evaluated. The physicochemical characteristics were determined by droplet size, interfacial tension and ζ‐potential and structurally verified by Fourier transform infrared spectroscopy (FTIR). Both CRG‐DSA and ALG‐DSA applied in O/W emulsion system exhibited smaller droplet sizes over the increasing concentration and were more stable during storage than native ones. The ζ‐potential of DSA‐modified seaweed polysaccharides has more negative charge compared with their native forms, owing to the additional carboxyl groups from modification reaction. In addition, DSA‐modified seaweed polysaccharides decreased the interfacial tension at soybean oil–water interface from 23.1 and 23.9 mN m−1 to 14.2 and 13.6 mN m−1, respectively. The successful modification reaction was confirmed by FTIR analysis. This study demonstrated that DSA‐modified seaweed polysaccharides may serve as prospective emulsifiers in food, pharmaceutical and other industrial fields.
Maternal blood pressure mediates the association between maternal obesity and infant weight gain in early postpartum
Authors: Berger Paige K. , Plows Jasmine F. , Jones Roshonda B. , Pollock Norman K. , Alderete Tanya L. , Ryoo Ji Hoon , Goran Michael I. 
Published: July 2019

SummaryBackgroundIt is unknown to what extent higher maternal blood pressure (BP) in early postpartum impacts the relationship between higher maternal weight status and greater infant weight gain in early postpartum.ObjectiveTo evaluate the mediating role of higher maternal BP at 1 month postpartum on the association between higher maternal weight status at 1 month postpartum and greater infant weight gain over 6 months postpartum.MethodsParticipants were 169 Hispanic mother‐infant pairs. Maternal body mass index (BMI) and BP were assessed at 1 month postpartum. Infant weight was measured at 1 and 6 months postpartum to calculate weight‐for‐age z scores (WAZ). Multiple linear regression models were used for prediction, and Sobel test was used to determine mediation.ResultsControlling for maternal pre‐pregnancy BMI, age, delivery mode, infant sex, and infant birth weight revealed that both maternal BMI (β = .29) and BP (β = .32) predicted infant WAZ gain (both P ≤ .03). However, the relationship between infant WAZ gain and maternal BMI was no longer significant after further adjustment for maternal BP, which remained significant (P < .05). Maternal BP explained 23.6% (Sobel T = 2.01) of the association between maternal BMI at 1 month and infant WAZ gain over 6 months.ConclusionOur data suggest that higher maternal weight status at 1 month postpartum is related to greater infant weight gain over 6 months postpartum, and this relationship is mediated by higher maternal BP at 1 month postpartum.
Perceived motivators, training supports and challenges to career advancement among pharmacists in the Malaysian public healthcare system
Authors: Chang Chee-Tao , Hassali Mohamed Azmi , HSS Amar-Singh , Lee Jason Choong Yin , Chan Huan-Keat 
Published: July 2019

AbstractObjectivesTo explore the perceived motivators, training supports and challenges to career advancement among fully and provisionally registered pharmacists (FRPs and PRPs) in the Malaysian public service.MethodsNine hundred and fifty-three pharmacists in the public service of Perak State, Malaysia, were invited for participation in an online survey that was conducted in October 2018. Based on a 5-point Likert scale, they were required to respond to 56 items, ranging from the perceived availability and importance of both motivators and training supports, the challenges to career advancement, to the awareness of the need for career planning. Their responses were subsequently dichotomized into ‘agree’/‘important’ and ‘disagree’/‘not important’.Key findingsFour hundred and eighty pharmacists participated in the survey, yielding a response rate of 51.2%. More than half of them agreed with the inflexibility of working time and the absence of a performance-based salary and promotion scheme. More than 80% of them also highly valued the training in both pharmacy-related areas and management. Apart from inadequate training, no specialization in pharmacy as a profession and the absence of a performance-based promotion scheme were identified as the major challenges to their career advancement. As compared with the PRPs, the FRPs had greater concern over the absence of a performance-based salary and promotion scheme, flexible working time and periodic feedback for their work performance.ConclusionsThe findings indicate the inadequacy of the current system in providing recognition, training, feedback for work performance and a clear career pathway to pharmacists in the Malaysian public service, which warrants a change.
Incumplimiento del salario mínimo en Europa central y oriental
Authors: GORAUS‐TAŃSKA Karolina , LEWANDOWSKI Piotr 
Published: July 2019

ResumenEn este estudio se analiza el incumplimiento del salario mínimo durante el periodo 2003–2012 en diez países de Europa central y oriental con salario mínimo obligatorio nacional. A partir de los datos de EU‐SILC y la metodología propuesta por Bhorat, Kanbur y Mayet (2013), se cuantifica la incidencia y magnitud del incumplimiento. Se realizan análisis de regresión sobre determinantes individuales, laborales y macroeconómicos. Aunque la incidencia permanece relativamente baja, los trabajadores a los que se dirigen las políticas de salario mínimo parecen los más expuestos a su incumplimiento. Con el tiempo, una mayor incidencia se asocia a una razón más alta entre salario mínimo y salario medio.
Molecular survey of the phosphoserine phosphatase involved in L‐serine synthesis by silkworms (Bombyx mori)
Authors: Haque M. R. , Hirowatari A. , Saruta F. , Furuya S. , Yamamoto K. 
Published: July 2019

AbstractPhosphoserine phosphatase (PSP) catalyses the synthesis of l‐serine via the phosphorylated pathway by facilitating the dephosphorylation of phosphoserine. A cDNA encoding PSP from the silkworm Bombyx mori (bmPSP) was isolated using reverse transcription‐PCR and then sequenced. The resulting clone encoded 236 amino acids with a molecular weight of 26 150, exhibiting 14–60% sequence identity with other PSPs. The recombinant PSP was overexpressed in Escherichia coli and purified. Kinetic studies showed that bmPSP possessed activity toward l‐phosphoserine, and Asp20, Asp22 and Asp204 in bmPSP were found to be critical for modulating bmPSP activity. Real‐time PCR analysis provided evidence that the amount of bmpsp transcript was reduced in middle silk glands of a sericin‐deficient silkworm strain. These findings revealed that bmPSP may play important roles in synthesizing one‐carbon donors of l‐serine, which is abundant in silk, as well as other cell metabolites in B. mori.
Not just a policy; this is for real. An affirmative action policy to encourage Aboriginal and Torres Strait Islander peoples to seek employment in the health workforce
Authors: Roseby Robert , Adams Karen , Leech Michelle , Taylor Karinda , Campbell Don 
Published: July 2019

AbstractDelivery of culturally safe healthcare is critical to ensuring access to high‐quality care for indigenous people. A key component of this is for Aboriginal and Torres Strait Islander people to be participants in the health workforce. The proportion of indigenous people in the health workforce should at least equate to the proportion in the population served. We describe the development and implementation of a successful affirmative action employment policy at Monash Health, one of Australia's largest Academic Health Centres, and provide perspective on its adoption.
Understanding the interplay of institutional logics and management practices in impact sourcing
Authors: Malik Fareesa , Nicholson Brian 
Published: July 2019

AbstractThis article draws on the evidence gathered from a research project in the area of global information technology outsourcing (GITO) involving a US‐based vendor of medical billing and transcription processing with a subsidiary in a remote area of Pakistan. It contributes to recent debates on impact sourcing—understood as GITO offering social value for marginalized groups in society. Prior research to date has focused on “social mission”–driven impact sourcing initiatives, but examples of mainstream “market‐driven” GITO's engagement in impact sourcing work are largely absent in the impact sourcing literature. Using qualitative methods, this study explores the interplay between institutional logics and management practices of a market‐driven GITO organization engaged in impact sourcing work. The findings identify family, community, and profession logics existing in the subsidiary location and management practices of the GITO organization responding to these logics. We abstract the practices into three mechanisms (ie, synchronization, bridging, and embedding) and present a process model that explains the dynamics of institutional logics and institutionally aligned management practices. This study offers both theoretical and practical implications to understand the implementation of impact sourcing initiatives in market‐driven GITO scenarios.
Significantly enhanced pyroelectric performance in novel sodium niobate‐based lead‐free ceramics by compositional tuning
Authors: Zhou Mingxing , Liang Ruihong , Zhou Zhiyong , Dong Xianlin 
Published: July 2019

AbstractIn this study, (1 − x)NaNbO3–xBa0.6(Bi0.5K0.5)0.4TiO3 (abbreviated as NN‐xBBKT, x = 0.05, 0.10, 0.15, and 0.20) lead‐free pyroelectric ceramics were synthesized by conventional solid‐state reaction method. Moreover, their microstructure, phase structure, dielectric, ferroelectric, piezoelectric, and pyroelectric characteristics were studied systematically. The X‐ray diffraction result showed that the phase structure of NN‐xBBKT ceramics changed from orthorhombic to tetragonal and finally became pseudocubic symmetry. The ferroelectric‐paraelectric phase transition temperature and depolarization temperature shifted to lower temperature with the increase in BBKT content. Furthermore, with increasing BBKT content, piezoelectric coefficient, figures of merit, and pyroelectric coefficient first increased and then decreased. The optimum pyroelectric properties (eg Fd = 0.81 × 10−5 Pa−1/2, Fv = 1.02 × 10−2 m2 C−1, Fi = 1.04 × 10−10 m V−1, and p = 3.11 × 10−8 C cm−2 K−1) were observed in sample composition with x = 0.15. More importantly, the pyroelectric coefficient of ceramic with x = 0.15 also displayed relatively high thermal stability because of high depolarization temperature (~110°C). These parameters demonstrate that the novel Pb‐free NaNbO3‐based ceramics form an important class of pyroelectric material with broad range of application prospect.
Managerial academic experience, external monitoring and financial reporting quality
Authors: Ma Zhiming , Novoselov Kirill E. , Zhou Kaitang , Zhou Yi 
Published: July 2019

AbstractThis study examines the effect of managerial academic experience on firms’ financial reporting quality. Using data from China, we find that firms with top managers possessing academic experience exhibit lower levels of both accrual and real earnings management, along with a lower probability of future restatements. This effect is more pronounced for firms with inefficient external monitoring, suggesting that the higher financial reporting quality is mainly explained by the managers’ intrinsic motivation to report truthfully. The results hold when we use firm fixed‐effect regressions, instrumental variable two‐stage regressions, and a propensity score matching (PSM) approach to mitigate the omitted variable and endogeneity concerns. Our study suggests that academic experience can serve as a source of valuable expertise for corporate executives.
Differentiation of human adipose derived stem cells into Leydig‐like cells with molecular compounds
Authors: Chen Yong , Li Chao , Ji Weiping , Wang Long , Chen Xianwu , Zhao Shenzhi , Xu Zhangye , Ge Renshan , Guo Xiaoling 
Published: July 2019

AbstractLeydig cells (LCs) are the primary source of testosterone in the testis, and testosterone deficiency caused by LC functional degeneration can lead to male reproductive dysfunction. LC replacement transplantation is a very promising approach for this disease therapy. Here, we report that human adipose derived stem cells (ADSCs) can be differentiated into Leydig‐like cells using a novel differentiation method based on molecular compounds. The isolated human ADSCs expressed positive CD29, CD44, CD59 and CD105, negative CD34, CD45 and HLA‐DR using flow cytometry, and had the capacity of adipogenic and osteogenic differentiation. ADSCs derived Leydig‐like cells (ADSC‐LCs) acquired testosterone synthesis capabilities, and positively expressed LC lineage‐specific markers LHCGR, STAR, SCARB1, SF‐1, CYP11A1, CYP17A1, HSD3B1 and HSD17B3 as well as negatively expressed ADSC specific markers CD29, CD44, CD59 and CD105. When ADSC‐LCs labelled with lipophilic red dye (PKH26) were injected into rat testes which were selectively eliminated endogenous LCs using ethylene dimethanesulfonate (EDS, 75 mg/kg), the transplanted ADSC‐LCs could survive and function in the interstitium of testes, and accelerate the recovery of blood testosterone levels and testis weights. These results demonstrated that ADSCs could be differentiated into Leydig‐like cells by few defined molecular compounds, which might lay the foundation for further clinical application of ADSC‐LC transplantation therapy.
Mannose 6‐phosphonate labelling: A key for processing the therapeutic enzyme in Pompe disease
Authors: Godefroy Anastasia , Daurat Morgane , Da Silva Afitz , Basile Ilaria , El Cheikh Khaled , Caillaud Catherine , Sacconi Sabrina , Schoser Benedikt , Charbonné Henry‐Vincent , Gary‐Bobo Magali , Morère Alain , Garcia Marcel , Maynadier Marie 
Published: July 2019

AbstractIn the search of a better enzyme therapy in Pompe disease, the conjugation of mannose 6‐phosphonates to the recombinant enzyme appeared as an enhancer of its efficacy. Here, we demonstrated that the increased efficacy of the conjugated enzyme is partly due to a higher intracellular maturation because of its insensitiveness to acid phosphatases during the routing to lysosomes.
Psychological distress and its association with job satisfaction among nurses in a teaching hospital
Authors: Ghawadra Sajed Faisal , Abdullah Khatijah Lim , Choo Wan Yuen , Phang Cheng Kar 
Published: July 2019

AbstractAim and objectivesTo determine the prevalence of psychological distress and its association with job satisfaction among nurses in a teaching hospital in Malaysia.BackgroundNurses constitute the majority of health care workers, and, compared with other professions, nursing profession is highly stressful and, hence, a cause of anxiety and depression. This may affect nurses' job satisfaction.MethodUsing self‐administered questionnaires, Depression Anxiety and Stress Scale (DASS‐21) and Job Satisfaction Scale for Nurses (JSS), a cross‐sectional study of 932 nurses from the inpatient departments of a teaching hospital was conducted in December 2017. Descriptive analyses and multiple logistic regressions were used for the analysis. The STROBE guideline was used in this study.ResultsThe overall prevalence of psychological distress was 41%. The prevalence of stress, anxiety and depression were 14.4%, 39.3% and 18.8%, respectively. It was found that single and widowed nurses had a higher level of stress, anxiety and depression compared with married nurses. In addition, nurses in the age of 26–30 years had a higher level of depression than nurses in other age groups. Also, nurses who worked in the paediatric departments had a higher level of depression compared with nurses in other departments. The majority of the nurses were satisfied with their job at 92.0%. Those nurses who were not satisfied were found to be significantly associated with a high level of stress and depression.ConclusionThis study revealed that the level of stress, anxiety and depression is high. Stress and depression were found to be associated with nurses' low job satisfaction.Relevance to clinical practiceStress and depression can affect nurses' job satisfaction, it is important for nursing managers to institute strategies to address this issue.
Clinical and pathological comparisons of adnexal torsion between pregnant and non‐pregnant women
Authors: Seo Seok K. , Lee Jun B. , Lee Inha , Yun Jisun , Yun Bo H. , Jung Yeon S. , Chon Seung J. 
Published: July 2019

AbstractAimWe evaluated and compared the clinical and pathological differences between pregnant and non‐pregnant women with adnexal torsion.MethodsWe retrospectively reviewed 239 women with adnexal torsion from January 2006 to December 2015 in a tertiary hospital. The clinical and pathological differences between pregnant and non‐pregnant women who underwent surgery for adnexal torsion were analyzed.ResultsThe most common pathologies were corpus luteum cysts in pregnant women and dermoid cysts in non‐pregnant women. Eight of the pregnant women (24.2%) had a history of exogenous ovarian stimulation, and their episodes were only caused by corpus luteum or a stimulated ovary. In pregnant women, 72.7% of the torsion occurred before the 14th week of gestation.ConclusionThe common pathology causing adnexal torsion was different, depending on the pregnancy status. Exogenous ovarian stimulation increases the risk of adnexal torsion, and the majority of episodes occurred in the first trimester in pregnant women.
Cannabinoid receptors in osteoporosis and osteoporotic pain: a narrative update of review
Authors: Wang Jing , Lu Hong-xia , Wang Jing 
Published: July 2019

Abstract

Objective
Osteoporosis is a skeletal disease with decreased bone mass and alteration in microarchitecture of bone tissue, and these changes put patients in risk of bone fracture. As a common symptom of osteoporosis and complication of osteoporotic fracture, chronic pain is a headache for clinicians. Nonsteroidal anti-inflammatory drugs (NSAIDs), selective COX-2 inhibitors and opioid drugs can temporarily reduce osteoporotic pain but have relevant side effects, such as addiction, tolerability and safety. The review summarized the recent advancements in the study of CB receptors in osteoporosis and osteoporotic pain and related mechanisms.

Key findings
Recent studies indicated the two nociceptive receptors, cannabinoid receptor (CB) and transient receptor potential vanilloid type 1 (TRPV1) channel, are co-expressed in bone cells and play important role in the metabolism of bone cells, suggesting that dualtargeting these 2 receptors/channel may provide a novel approach for osteoporotic pain. In addition, both CB receptor and TRPV1 channel are found to be expressed in the glial cells which play vital role in mediating inflammation, chronic pain and metabolism of bone cells, suggesting a role of glial cells inosteoporotic pain.

Summary
Multiple-targeting against glial cells, CB receptors and TRPV1 channel may be one effective therapeutic strategy for osteoporotic pain in the future, following the elucidation of the complicated mechanism.
Non‐Random Distribution and Ecophysiological Differentiation of Pyropia Species (Bangiales, Rhodophyta) Through Environmental Gradients
Authors: Zapata Javier , Meynard Andrés , Anguita Cristóbal , Espinoza Camila , Alvear Paula , Kumar Manoj , Contreras‐Porcia Loretto 
Published: July 2019

Recently 18 Bangiales seaweed species were reported for the Chilean coast, including Pyropia orbicularis and Pyropia variabilis (large [LM] and green [GM] morphotypes). Porphyra/Pyropia spp. occur mainly in the upper intertidal where desiccation stress is triggered by tidal fluctuations. However, the influence of environmental and ecophysiological variables and seasonal differences on Porphyra/Pyropia (microhabitats) intertidal distributions is unknown. Accordingly, we determined (i) the effect of environmental variables (temperature [T], relative humidity [RH], and photosynthetically active radiation [PAR]) and season on distribution, and (ii) physiological (cellular activity and lipid peroxidation [LPX]) and molecular responses (antioxidant enzymes expression at biochemical and transcript level) to desiccation stress in both Pyropia species and morphotypes (common garden experiment, on flat rocky platforms). Multivariate analyses of coverage and abundance in relation to environmental variables revealed a significant effect of temperature on P. variabilis GM distribution, GM dominating almost exclusively on rocky walls (where lowest PAR and T values but maximum RH were registered). Conversely, Pyropia orbicularis and Pyropia variabilis LM were found in high abundance on flat rocky platforms in summer, LM and GM also dominating flat rocky platforms in winter and spring. LPX and catalase activity did not differed among species in summer, while in winter activity and transcription of cat were higher in P. orbicularis than P. variabilis. Results suggest that tolerance to environmental stresses such as temperature could regulate the occurrence of P. variabilis GM on rocky walls; conversely, abundances of P. variabilis and P. orbicularis on flat rocky platforms would be also regulated by other abiotic and/or biotic factors.
Robust consumption‐investment problem under CRRA and CARA utilities with time‐varying confidence sets
Authors: Liang Zongxia , Ma Ming 
Published: July 2019

AbstractWe consider a robust consumption‐investment problem under constant relative risk aversion and constant absolute risk aversion utilities. The time‐varying confidence sets are specified by Θ, a correspondence from [0, T] to the space of the Lévy triplets, and describe a priori drift, volatility, and jump information. For each possible measure, the log‐price processes of stocks are semimartingales, and the triplet of their differential characteristics is almost surely a measurable selector from the correspondence Θ. By proposing and investigating the global kernel, an optimal policy and a worst‐case measure are generated from a saddle point of the global kernel, and they constitute a saddle point of the objective function.
Option pricing with orthogonal polynomial expansions
Authors: Ackerer Damien , Filipović Damir 
Published: July 2019

AbstractWe derive analytic series representations for European option prices in polynomial stochastic volatility models. This includes the Jacobi, Heston, Stein–Stein, and Hull–White models, for which we provide numerical case studies. We find that our polynomial option price series expansion performs as efficiently and accurately as the Fourier‐transform‐based method in the nested affine cases. We also derive and numerically validate series representations for option Greeks. We depict an extension of our approach to exotic options whose payoffs depend on a finite number of prices.
Functional Coefficient Cointegration Models Subject to Time–Varying Volatility with an Application to the Purchasing Power Parity
Authors: Tu Yundong , Wang Ying 
Published: July 2019

AbstractThis paper analyses functional coefficient cointegration models with both stationary and non‐stationary covariates, allowing time‐varying (unconditional) volatility of a general form. The conventional kernel weighted least squares (KLS) estimator is subject to potential efficiency loss, and can be improved by an adaptive kernel weighted least squares (AKLS) estimator that adapts to heteroscedasticity of unknown form. The AKLS estimator is shown to be as efficient as the oracle generalized kernel weighted least squares estimator asymptotically, and can achieve significant efficiency gain relative to the KLS estimator in finite samples. An illustrative example is provided by investigating the Purchasing Power Parity hypothesis.