bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agamben, John Chrysostom and Alternative Politics
Authors: Bekos John 
Published: July 2018

Abstract
This article presents an alternative use of The Church and the Kingdom, a homily that Giorgio Agamben addressed to the Bishop of Paris and high-ranked Church officials at Notre Dame Cathedral in Paris, in 2009. Taking advantage of the biblical and patristic sources of the homily, this article places the speech within the Christian tradition, treating it as if it was a Christian homily. It argues that the Church and the Kingdom lay the foundations for the new political comprising a dialectical tension between the State and the Church. The alternative politics of this new political is further developed by bringing together John Chrysostom, the philosopher Agamben and the theologian Stanley Hauerwas. This coming together leads to a politics of a life as strangers, sojourners and refugees.
Note on rare snake eels (Anguilliformes: Ophichthidae) and additional data on three Neenchelys recently described from Taiwan
Authors: HO HSUAN-CHING , HIBINO YUSUKE , HUANG JIAN-FU 
Published: July 2018

Three rare snake eel species, Allips concolor McCosker, 1972, Neenchelys daedalus McCosker, 1982, and Apterichtus moseri (Jordan & Snyder, 1901), were newly collected from Taiwan. The distribution ranges of the first two species are now extended to the South China Sea off southern Taiwan and that of the third is extended southward to off northwestern Taiwan. Supplemental data for three recently described species, Neenchelys diaphora, N. gracilis and N. similis, from Taiwan are provided.
Effects of Touch, Voice, and Multimodal Input, and Task Load on Multiple-UAV Monitoring Performance During Simulated Manned-Unmanned Teaming in a Military Helicopter
Authors: Levulis Samuel J. , DeLucia Patricia R. , Kim So Young 
Published: July 2018

Objective: We evaluated three interface input methods for a simulated manned-unmanned teaming (MUM-T) supervisory control system designed for Air Mission Commanders (AMCs) in Black Hawk helicopters. Background: A key component of the U.S. Army’s vision for unmanned aerial vehicles (UAVs) is to integrate UAVs into manned missions, called MUM-T (Department of Defense, 2010). One application of MUM-T is to provide the AMC of a team of Black Hawk helicopters control of multiple UAVs, offering advanced reconnaissance and real-time intelligence of flight routes and landing zones. Method: Participants supervised a (simulated) team of two helicopters and three UAVs while traveling toward a landing zone to deploy ground troops. Participants classified aerial photographs collected by UAVs, monitored instrument warnings, and responded to radio communications. We manipulated interface input modality (touch, voice, multimodal) and task load (number of photographs). Results: Compared with voice, touch and multimodal control resulted in better performance on all tasks and resulted in lower subjective workload and greater subjective situation awareness, ps < .05. Participants with higher spatial ability classified more aerial photographs ( r = .75) and exhibited shorter response times to instrument warnings ( r = −.58) than participants with lower spatial ability. Conclusion: Touchscreen and multimodal control were superior to voice control in a supervisory control task that involved monitoring visual displays and communicating on radio channels. Application: Although voice control is often considered a more natural and less physically demanding input method, caution is needed when designing visual displays for users sharing common communication channels.
An Upper Extremity Risk Assessment Tool Based on Material Fatigue Failure Theory: The Distal Upper Extremity Tool (DUET)
Authors: Gallagher Sean , Schall Mark C. , Sesek Richard F. , Huangfu Rong 
Published: July 2018

Objective: Musculoskeletal tissues repeatedly loaded in vitro fail in accordance with material fatigue failure theory, and there is evidence to suggest that the same process occurs in vivo. The current paper presents a new upper extremity risk assessment tool, the Distal Upper Extremity Tool (DUET), predicated on material fatigue failure theory. Methods: DUET requires an estimate of force exertion level and the number of repetitions performed to derive estimates of damage and probabilities of experiencing a distal upper extremity outcome. Damage accrued over multiple tasks may be summed to estimate the cumulative damage (CD) accrued over a workday. Validation of this tool was performed using five distal upper extremity (DUE) outcomes (involving medical visits and pain) from an existing epidemiological database involving data from six automotive manufacturing plants. Logistic regression was used to assess the association of the log of the DUET CD measure to DUE outcomes. Results: Results demonstrated that the log of the DUET CD measure was highly associated with all five DUE outcomes in both crude analyses and those adjusted for site, age, gender, and body mass index ( p < .01). A model relating the continuous DUET log CD score to the probability of the DUE outcome Injury + Pain Last Year was developed, which demonstrated a significant dose-response relationship. Conclusions: Results suggest that fatigue failure–based risk assessment techniques are highly associated with DUE outcomes and provide support for the notion that an underlying fatigue failure process may be involved in the development of upper extremity musculoskeletal disorders.
Signal Detection Theory (SDT) Is Effective for Modeling User Behavior Toward Phishing and Spear-Phishing Attacks
Authors: Martin Jaclyn , Dubé Chad , Coovert Michael D. 
Published: July 2018

Objective: To examine the utility of equal-variance signal detection theory (EVSDT) for evaluating and understanding human detection of phishing and spear-phishing e-mail scams. Background: Although the majority of cybersecurity breaches are due to erroneous responses to deceptive phishing e-mails, it is unclear how best to quantify performance in this context. In particular, it is unclear whether equal variances can safely be assumed in the SDT model, or, relatedly, whether degree of targeting, or threat level, primarily affects mean separation or evidence variability. Method: Through an online inbox simulation, the present research found that differences in susceptibility to phishing and spear-phishing e-mails could be carefully quantified with respect to detection accuracy and response bias through the use of an EVSDT framework. Results: The results indicated that EVSDT-based point metrics are effective for modeling and measuring phishing susceptibility in the inbox task, without the need for parameter estimation or model comparison involving unequal-variance SDT (UVSDT). Threat level modulated mean separation, with no effects on signal variances. Conclusion: These findings support the viability of using EVSDT to initially assess and subsequently monitor training effectiveness for phishing susceptibility, thereby providing measures that are superior to more intuitive metrics, which typically confound an individual’s bias and accuracy. Effects of threat level mapped clearly onto distribution means with no effect on variances, suggesting phishing susceptibility primarily reflects temporally stable discriminative characteristics of observers. Notably, results indicated that people are particularly poor at identifying spear-phishing e-mail threats (demonstrating only 40% accuracy).
Treatment Delays in Primarily Resected Oropharyngeal Squamous Cell Carcinoma: National Benchmarks and Survival Associations
Authors: Morse Elliot , Judson Benjamin , Husain Zain , Burtness Barbara , Yarbrough Wendell G. , Sasaki Clarence , Cheraghlou Shayan , Mehra Saral 
Published: July 2018

ObjectiveTo characterize treatment delays in surgically treated oropharyngeal cancer, identify factors associated with delays, and associate delays with survival.Study DesignRetrospective cross‐sectional analysis.SettingCommission on Cancer–accredited institutions.Subjects and MethodsWe identified patients in the National Cancer Database with surgically treated oropharyngeal cancer. We characterized the durations of diagnosis‐to‐treatment initiation, surgery‐to‐radiation treatment, radiation treatment duration, total treatment package, and diagnosis‐to‐treatment end intervals as medians. We associated delays with patient, tumor, and treatment factors via multivariable logistic regression analysis and with overall survival by Cox proportional hazards regression.ResultsIn total, 3708 patients met inclusion criteria. Median durations of diagnosis‐to‐treatment initiation, surgery‐to‐radiation treatment, radiation treatment duration, total treatment package, and diagnosis‐to‐treatment end intervals were 27, 42, 47, 90, and 106 days, respectively. Medicaid and human papillomavirus (HPV) negativity were associated with delays. Delayed total treatment package and diagnosis‐to‐treatment end intervals were associated with decreased survival (hazard ratio [HR] = 1.81 [1.29‐2.54], P =. 001 and HR = 1.97 [1.39‐2.78], P <. 001, respectively); this was maintained following HPV stratification. Delays in the surgery‐to‐radiation treatment interval were associated with decreased overall survival in HPV‐negative but not HPV‐positive patients (HR = 2.05 [1.19‐3.52], P =. 010 and HR = 1.15 [0.74‐1.80], P =. 535, respectively). Diagnosis‐to‐treatment initiation and radiation treatment duration were not associated with overall survival in the overall cohort (HR = 1.21 [0.86‐1.72], P =. 280 and HR = 1.40 [0.99‐1.99], P =. 061, respectively); however, following stratification, delayed radiation treatment duration approached significance in HPV‐negative but not HPV‐positive patients (HR = 1.60 [0.96‐2.68], P =. 072 and HR = 1.35 [0.84‐2.18], P =. 220).ConclusionTreatment durations identified here can serve as national benchmarks and for institutions to compare quality to their peers. Distinct benchmarks should be applied to HPV‐negative and HPV‐positive patients.
Dose-response effects of omega-3 on platelet aggregation: an observational study
Authors: Kander Thomas , Lindblom Erik , Schött Ulf 
Published: July 2018

Objective This study aimed to evaluate the dose-response effects of supplemental omega-3 fatty acids on platelet function in healthy volunteers. Methods Twelve healthy volunteers ingested a normal supplemental dose of 1260 mg omega-3 fatty acids daily for 5 days, followed by a high dose of 2520 mg daily for another 5 days. Multiple electrode aggregometry (MEA) with four different agonists was used to measure platelet aggregation before and after the normal- and high-dose regimes. In vitro spiking using physiological doses of omega-3 fatty acids was also performed to determine whether MEA is capable of detecting a platelet-inhibiting effect due to omega-3 fatty acids. Results There were no differences in platelet aggregation measured by the MEA assay in healthy volunteers after intake of either the normal or high dose of omega-3 fatty acids. In the in vitro experiment, a platelet-inhibiting effect of omega-3 fatty acids was shown by an arachidonic acid agonist in MEA . Conclusions Supplemental omega-3 fatty acids do not evoke their positive health effects through inhibition of platelet aggregation measurable with MEA.
Cardiosphere-Derived Cells Attenuate Inflammation, Preserve Systolic Function, and Prevent Adverse Remodeling in Rat Hearts With Experimental Autoimmune Myocarditis
Authors: Nana-Leventaki E. , Nana M. , Poulianitis N. , Sampaziotis D. , Perrea D. , Sanoudou D. , Rontogianni D. , Malliaras K. 
Published: July 2018

Background: Cardiosphere-derived cells (CDCs) have yielded promising efficacy signals in early-phase clinical trials of ischemic and nonischemic cardiomyopathy. The potential efficacy of CDCs in acute myocarditis, an inflammatory cardiomyopathy without effective therapy, remains unexplored. Given that CDCs produce regenerative, cardioprotective, anti-inflammatory, and anti-fibrotic effects (all of which could be beneficial in acute myocarditis), we investigated the efficacy of intracoronary delivery of CDCs in a rat model of experimental autoimmune myocarditis. Methods: Lewis rats underwent induction of experimental autoimmune myocarditis by subcutaneous footpad injection of purified porcine cardiac myosin supplemented with Mycobacterium tuberculosis on days 1 and 7. On day 10, rats were randomly assigned to receive global intracoronary delivery of 500 000 CDCs or vehicle. Global intracoronary delivery was performed by injection of cells or vehicle into the left ventricular (LV) cavity during transient occlusion of the aortic root. Rats were euthanized 18 days after infusion. Cardiac volumes and systolic function were assessed by serial echocardiography, performed on days 1, 10, and 28. Myocardial inflammation, T-cell infiltration, and cardiac fibrosis were evaluated by histology. Results: Experimental autoimmune myocarditis was successfully induced in 14/14 rats that completed follow-up. Left ventricular ejection fraction (LVEF) and volumes were comparable on days 1 and 10 between groups. CDC infusion resulted in increased LVEF (81.5% ± 3% vs 65.4% ± 8%, P < .001) and decreased LV end-systolic volume (43 ± 15 vs 100 ± 24 μL, P < .001) compared to placebo administration at 18 days post-infusion. Cardiosphere-derived cell infusion decreased myocardial inflammation (7.4% ± 7% vs 20.7% ± 4% of myocardium, P = .007), cardiac fibrosis (16.6% ± 13% vs 38.1% ± 3% of myocardium, P = .008), and myocardial T-cell infiltration (30.4 ± 29 vs 125.8 ± 49 cells per field, P = .005) at 18 days post-infusion compared to placebo administration. Conclusion: Intracoronary delivery of CDCs attenuates myocardial inflammation, T-cell infiltration, and fibrosis while preventing myocarditis-induced systolic dysfunction and adverse remodeling in rats with experimental autoimmune myocarditis.
Association between periacetabular osteotomy and hip dysplasia among relatives: a cross-sectional study
Authors: Simonsen Pernille O , Hertz Jens M , Søballe Kjeld , Mechlenburg Inger 
Published: July 2018

Introduction: Previous studies indicate a familial predisposition for developmental dysplasia of the hip (DDH), especially among first-degree relatives. This study investigated the association between unilateral or bilateral periacetabular osteotomy (PAO), family history of DDH and the degree of relationship with relatives with DDH. Material and methods: This cross-sectional study consisted of 815 consecutive patients undergoing PAO from 1998 to 2016. Information regarding unilateral or bilateral PAO, gender and age at the time of surgery was obtained from the clinical PAO database at Aarhus University Hospital, Denmark. A questionnaire was used to collect information about the family history of DDH. The association was assessed by logistic regression analysis, and divided into 615 unilateral and 200 bilateral PAO patients. Results: PAO patients with a first-degree relative with DDH had a 72% (odds ratio [OR] = 1.72, 95% confidence interval [CI] 1.17; 2.50) higher occurrence of bilateral PAO than patients without family relatives with DDH. This association was statistically significant ( p = 0.005), even when adjusting for gender and age at the time of surgery. A similar association was not demonstrated among any other degrees of relationship. Conclusion: Danish patients with DDH and a first-degree relative with DDH have an increased risk of being surgically treated with bilateral PAO compared to patients without a family history of DDH. Patients undergoing bilateral PAO may therefore have a strong genetic predisposition for DDH. This study reveals a potential group of patients with DDH where genetic analysis may identify relatives with a higher risk of the disease.
Evaluating a Glucose-Sensor-Based Tool to Help Clinicians and Adults With Type 1 Diabetes Improve Self-Management Skills
Authors: Toschi Elena , Fisher Lawrence , Wolpert Howard , Love Michael , Dunn Timothy , Hayter Gary 
Published: July 2018

Background: The goal of this uncontrolled pilot study was to assess the feasibility of a self-care management mobile app, called Sugar Sleuth, which incorporates the FreeStyle Libre™ glucose sensor, to help clinicians and people with type 1 diabetes (PWD) identify and mitigate self-care behaviors that contribute to glucose variability. Methods: PWDs with a baseline A1c between 7.5 and 9.0% used the mobile app for 14 weeks. The app prompted the PWD to enter the suspected cause of detected glycemic excursions, and to record food and insulin information. PWDs met with clinicians to collaboratively review data, identify challenges, and devise a specific self-care plan. Outcome measures included a single glycemic outcome score (SGOS) and attitude rating scales to better understand how participant attitudes could affect glycemic outcome. Results: Thirty enrolled PWDs had a mean age of 55 ± 2.6 years, and a mean diabetes duration of 32 ± 2.9 years. A significant average reduction in A1c of 0.5 ± 0.07% ( P < .01) and in mean daily carbohydrate intake of 43 ± 21 grams ( P = .05) was found. No statistically significant change in glycemic metrics, body weight, or total daily insulin dose was found. A significant negative association occurred between SGOS and “hypoglycemia tolerance” ( P = .04), and a positive correlation occurred that approached significance with “motivation to change behavior” ( P = .06). Conclusions: These findings suggest that this mobile app system, in conjunction with CGM, provides a useful platform for helping clinicians and adults with T1D improve self-management skills to improve glycemic control.
Acquired urea cycle amino acid deficiency and hyperammonaemic encephalopathy in a cat with inflammatory bowel disease and chronic kidney disease
Authors: Dor Cécile , Adamany Jessica L , Kisielewicz Caroline , de Brot Simone , Erles Kerstin , Dhumeaux Marc P 
Published: July 2018

Case summary A 5-year-old male neutered Persian cat was referred for investigation of a 4 week history of weight loss, inappetence and intermittent vomiting. Chronic kidney disease (CKD) and inflammatory bowel disease were diagnosed, and despite immunosuppressive therapy and assisted enteral nutrition, the cat experienced persistent anorexia, vomiting and severe weight loss. After 2 additional weeks of treatment, the cat developed acute-onset neurological signs associated with severe hyperammonaemia and was euthanased. Plasma amino acid assessment revealed deficiency of several amino acids involved in the urea cycle, including arginine. Relevance and novel information To our knowledge, this is the first reported case of an acquired urea cycle amino acid deficiency without nutritional deprivation in a cat. Several contributing factors were suspected, including intestinal malabsorption and CKD. This case demonstrates the importance of urea cycle amino acids in feline metabolism and possible necessity for parenteral supplementation, particularly in the context of persistent weight loss despite adequate enteral nutrition.
Bilateral Solar Retinopathy After Gazing at the Great American Eclipse
Authors: Banda Himanshu K. , Dang Sabin , Shah Anjali G. , Shah Gaurav K. 
Published: July 2018

Purpose: We report a case of bilateral solar retinopathy following the Great American Eclipse on August 21, 2017. We summarize findings on multimodal imaging and risk factors associated with solar retinopathy. Methods: A teenage boy presented with painless vision loss 4 days following viewing a total solar eclipse. Funduscopic examination, optical coherence tomography, and fluorescein angiography revealed findings characteristic of solar retinopathy. Multifocal electroretinography was also performed. We add to the literature the first reported case of solar retinopathy following the Great American Eclipse. Results: The patient was observed with serial examinations over several weeks. Gradual trend toward visual recovery was noted on imaging. Conclusions: In combination with clinical history of sungazing and funduscopic examination, distinct findings on imaging help secure a diagnosis of solar retinopathy. Visual symptoms in solar retinopathy generally improve over time. Appropriate protective measures with counseling and filtered eyewear are recommended for eclipse viewers.
Multi-slice frozen phonon simulations of high-angle annular dark field scanning transmission electron microscopy images of the structurally and compositionally complex Mo–V–Nb–Te oxide catalyst
Authors: Blom Douglas A. , Vogt Thomas 
Published: July 2018

AbstractWe report frozen phonon multi-slice image simulations for the complex oxidation catalyst M1. Quantitative analysis of the simulations suggests that the detailed order of the cations along the electron propagation direction in a [001] zone axis orientation can lead to different high-angle annular dark field signals from atomic columns with identical composition. The annular dark field signal varies linearly with atomic percent V, and the spread of intensities due to the atomic species order is of similar magnitude to the intensity difference due to ± 5% V.
The effect of ultrasound pretreatment on some selected physicochemical properties of black cumin (Nigella Sativa)
Authors: Moghimi Masoumeh , Farzaneh Vahid , Bakhshabadi Hamid 
Published: July 2018

Abstract
Background
In the present study, the effects of ultrasound pretreatment parameters including irradiation time and power on the quantity of the extracted phenolic compounds quantity as well as on some selected physicochemical properties of the extracted oils including oil extraction efficiency, acidity and peroxide values, color, and refractive index of the extracted oil of black cumin seeds with the use of cold press have been studied.

Methods
For each parameter, three different levels (30, 60, and 90 W) for the ultrasound power and (30, 45, and 60 min) and for the ultrasound irradiation time were studied. Each experiment was performed in three replications.

Results
The achieved results revealed that, with enhancements in the applied ultrasound power, the oil extraction efficiency, acidity value, total phenolic content, peroxide value, and color parameters increased significantly (P < 0.01). Enhancements in ultrasound irradiation time have not significantly increased the oil extraction efficiency, acidity value, total phenolic content, and peroxide value as well as the oil refractive index (P < 0.05). As the highest oil extraction efficiency (39.93%) was obtained from the seeds when the applied ultrasound power and time were 90 W and 60 min respectively, and the lowest acidity value of oil was achieved once the applied power and time of ultrasound were 30 W and 30 min respectively. The application of ultrasound as pretreatment has not shown any significant effects on the refractive index of the extracted oils (P > 0.05).

Conclusions
In summary, it could be mentioned that the application of ultrasound pretreatment in the oil extraction might improve the oil extraction efficiency, the extracted oil’s quality, and the extracted phenolic compounds content.