bluuebunny/crossref_metadata_2025_split huggingface dataset:
27 Defining a robust sow: swine nutrition perspective on reproduction and lactation
Authors: DeRouchey Joel M , Tokach Mike D , Goodband Robert D , Woodworth Jason C , Dritz Steve S , Menegat Mariana Boscato 
Published: July 2019

Abstract
Improvements in modern sow prolificacy have markedly increased the number of pigs weaned, thus the ability of sows to provide nutrients to support fetal growth and milk production has been enhanced. The goals of the gestation nutrition program consist of meeting the nutrient requirements for maintenance and growth and for adequate conceptus development, while managing body condition. Early gestation represents the best opportunity for replenishing body reserves, whereas in late gestation, both estimated protein deposition and energy requirement are exponentially increased and directed towards fetal growth and mammary development. Increased feed intake after breeding has been presumed to be detrimental to embryo survival; however, data with modern line sows demonstrates to feed thin sows to recover body condition as quickly as possible while avoiding feed deprivation immediately after breeding. Importance of body condition scoring remains unchanged: feed thin sows to bring back to adequate body condition and prevent over-conditioned sows at farrowing. A recent meta-analysis showed increasing late gestation feed intake seems to modestly improve piglet birth weight by 28 g per piglet in gilts and sows. Also, recent findings in gestating sows suggest modern genotypes have improved feed efficiency and propensity for growth. Therefore, increasing energy intake during late gestation has a modest effect on piglet birth weight and a negative effect on stillborn rate. Historically, lactation catabolism impacted subsequent reproductive performance of sows, particularly in first-parity. However, contemporary sows appear to be increasingly resistant to the negative effects of lactational catabolism. Even so, continued emphasis on maximizing lactation feed intake is critical to support milk production and prevent excessive lean tissue mobilization. Research data suggests that ad libitum feeding and offering lactation diets during the wean-to-estrus interval is not needed. Modern genetic sow lines appear to be more robust from a nutritional perspective than in the past.
34 Present and future of genomic test reporting in the cattle industry
Authors: Tait Rich , Ferretti Ryan , Simpson Barry , Walker Jeremy , Parham Jamie , Wu Xiao-Lin , Bauck Stewart 
Published: July 2019

Abstract
A series of custom low density (LD) SNP genotyping platforms have been created over the years. Recognized by the GeneSeek Genomic Profiler (GGP) nomenclature, these SNP arrays have increased in size as new versions were created, such as: GGP-LD-v1 (n = 8,762), GGP-LD-v2 (n = 20,057), GGP-LD-v3 (n = 26,151), GGP-LD-v4 (n = 30,108), and GGP Bovine 50K (n = 47,843), all of which contained a base of the Illumina Bovine LD array (n = 7,931) and then added SNPs to provide maximum information content (Shannon Entropy) and optimal genomic coverage into target populations without specific restrictions on overlap to historical commercial arrays such as the Illumina Bovine 50K (n = 54,001). Our approach has been to select SNP content which originated on the Illumina Bovine HD array (n = 777,962) or the GGP F250 functional SNP array (n = 221,115). This approach produced GGPs which: 1) have a larger number of SNPs that meet quality control metrics for minor allele frequency and Hardy-Weinberg segregation testing; 2) have superior imputation accuracy to the Illumina HD array in target populations; and 3) have causative SNPs or SNPs in closer LD with causative mutations for functional genomics studies and increased utility across populations. These design features have not always been utilized by users of the GGP portfolio. In some cases, users have imputed from GGP content back to the Illumina Bovine 50K SNP content within their population because that was the earliest process they developed in their evaluation system. This approach ignores the innovation and potential utility designed into the GGP chips for breeders within those organizations. We do not look back to prior SNP arrays for content definition for the purpose of bridging content from current arrays to the past. Instead, our vision is to continue to innovate, on a routine basis, which SNPs we provide to customers, so that their genetic evaluations can continue to evolve and improve into the future.
40 Alternative forages for dairy heifers
Authors: Akins Matthew , Remick Elizabeth , Su Huawei , Li Lingyan , Grisham Abbey , Coblentz Wayne K 
Published: July 2019

Abstract
Dairy heifers have moderate energy needs with diets containing high proportions of corn silage, often exceeding needs of pregnant heifers. Use of moderate energy forages to decrease energy and increase NDF content has been successful to control intake and growth of pregnant heifers. Several forages could be used, including cereal grain forages/straws, warm season perennial grasses, sorghum forages, and corn stover. Higher NDF content diets control intake through rumen fill as heifers eat approximately 1% of bodyweight in NDF daily. Research at the University of Wisconsin found reduced intakes and more desirable gains for pregnant heifers fed diets that included either corn stover, wheat straw, or eastern gamagrass (0.8–1.0 kg gain/day) compared with heifers fed an alfalfa/corn silage diet (1.2 kg gain/day). A study feeding alfalfa stemlage also found that heifers had more desirable gains (0.9–1.0 kg/day) when fed diets with stemlage or straw than heifers fed an alfalfa/corn silage diet. Sorghum forages may also work to partially replace corn silage in the forage program, with an opportunity to double-crop with cereal grain forages. Wisconsin studies show that sorghum forages can have similar or greater yields than corn silage when planted in early to mid-June and harvested once in the fall, with sorghums being more responsive to irrigation and nitrogen than corn. Most sorghums had similar or greater yields than corn silage when fertilized at 22–45 kg N/acre or irrigated at 50–75% of levels recommended for corn. A recent study found heifers fed sorghum-sudangrass silage based diets had lower intakes due to higher NDF content leading to more optimal daily gains (0.9 kg/d) than heifers fed a corn silage/alfalfa silage/grass hay diet that had similar protein and energy content, but was lower in NDF content. Use of alternative forages can help control nutrient intake and thus growth, and can also help control costs and improve nutrient/manure management by lowering intakes and forage production costs.
44 Amino acids in livestock: A historical perspective
Authors: Haydon Keith D , Dean Boyd R 
Published: July 2019

Abstract
The advent of commercially viable synthetic amino acids (AA) and least cost formulation (LCF) have fundamentally changed swine and poultry diets over the past 40 years. Amino acids can be produced by chemical synthesis, hydrolysis of intact proteins and fermentation. Chemical synthesis of AA was first reported by Strecker (1850). Discovery of glutamate as the basis of Umami taste category (1907) spurred commercial AA production by hydrolysis. The discovery of commercially viable fermentative production of glutamate, by Kyowa Hakko Kogyo Co. (1957), revolutionized AA production. Their parallel discovery of lysine (Lys) production, using a natural C. glutmanicum mutant subsequently followed. This led to further screening for bacterial mutants for threonine (Thr, 1961), tryptophan (Trp, 1972), valine (Val, 1959) and isoleucine (Ile, 1972). The next milestone occurred with development of the first main-frame LCF programs (1960s). The first commercial application of dietary AA involved methionine (Met) for poultry, followed closely by Lys in swine. Use of other synthetic AA was cost-prohibitive, but they served as research tools. The next revolution involved recombinant DNA technology (1980s), which dramatically increased AA yield and reduced production cost. Simultaneously, development of PC based LCF enabled cost effective formulation. Subsequently, growth-derived AA ratio’s emerged from the labs of Fuller (1989) and Baker (1992). Patent expirations in the late 1980s led to new companies that produced rapid advances in fermentation methods, with new recombinant strains. Production cost declined further for Lys (1988), and production efficiencies allowed Thr (1995) and Trp (2000) to enter commercial diets. Advances in fermentation technology have enabled production of all ten essential AA. Extensive AA displacement of protein supplements has led to an ever-expanding global tonnage of AA for food and pet animals. With routine addition of 4–6 AA in swine diets, we question whether non-essential AA nitrogen may emerge as limiting (essential).
54 Lipid nutrition and gut health of pigs
Authors: Lauridsen Charlotte 
Published: July 2019

Abstract
Lipids and fatty acids play major roles in relation to mucosal immune responses, epithelial barrier functions, oxidative stress and inflammatory reactions. The composition of fatty acids and their molecular structures (chain length and number of double bonds) influences digestion, absorption and metabolism of the dietary fat, as well as the bioactivity of the fatty acids. Piglets post weaning having immature intestines and immune functions are very vulnerable towards invading microorganisms. Manipulation of the milk fatty acid composition via the sow nutrition, or inclusion of dietary fat sources in the feed, may be used as a strategic tool to enhance pig performance and their gut health pre- and post weaning. Medium-chained fatty acids (MCFA) are absorbed directly into the portal blood and may contribute with immediate energy for the piglet. In addition, the MCFA possess antibacterial effects. The essential fatty acids, linoleic and linolenic fatty acids, form the building blocks for the longer –chained polyunsaturated n-3 and n-6 fatty acids. Their conversion into n-3 and n-6 eicosanoids influence the inflammatory reactions and the immune responses upon bacterial challenge. The proportion of unsaturated fatty acids in the cell membranes influence the susceptibility to oxidative stress. Oxidative stress accompanies infectious diseases, and if uncontrolled, the development of the lipid peroxides may be harmful for the epithelial barrier function. The aim of this presentation is to review how dietary fatty acid composition during critical phases of pigs’ lives can support a normal immune system and modulate resistance to infectious diseases of pigs, and influence growth of the pig. Furthermore, factors that can enhance oxidative stress (e.g. polyunsaturated fatty acids), uncontrolled inflammatory reactions (e.g. high ratio of n-6 to n-3 fatty acids in cellular membranes), and limit immune development (such as deficiency of fat-soluble vitamins), and be harmful for the pig gut health are addressed.
61 The impact of selective phenotyping and genotyping over generations in beef cattle
Authors: Reis Andrea Plotzki , da Costa Rodrigo Fagundes , Silva Fabyano Fonseca e , Cardoso Fernando Flores , Spangler Matthew L 
Published: July 2019

Abstract
The aim of this study was to investigate selective phenotyping to maintain adequate prediction accuracy. A simulation was conducted, with 10 replicates, using QMSim to mimic the structure and size of a Braford population. A population with 50 generations, 500 animals per generation, was created with phenotyping and genotyping beginning in generation 11. The scenarios investigated were: 1) Randomly phenotype and genotype 10, 25, 50, 75, and 100% of individuals each generation and; 2) Randomly phenotype and genotype 10, 25, 50, 75, and 100% of individuals in every-other generation. Estimated breeding values (EBV) were obtained using single-step GBLUP and accuracy was determined as the correlation between true BV from simulation and those estimated from the blupf90 family of programs. For scenarios where phenotyping and genotyping occurred every generation, EBV accuracies in generation 11 and 50 ranged from 0.32 to 0.32, 0.42 to 0.43, 0.49 to 0.51, 0.53 to 0.56 and 0.57 to 0.59 when 10, 25, 50, 75, and 100% of animals were chosen, respectively. The highest accuracies were 0.40 and 0.50 in generation 38 for scenarios 10 and 25%; 0.56, 0.61 and 0.64 in generation 40 for scenarios 50, 75 and 100%, respectively. When animals were selected every-other generation, EBV accuracy in generation 11 and 50 ranged from 0.24 to 0.26, 0.36 to 0.36, 0.43 to 0.42, 0.48 to 0.44 and 0.53 to 0.48 for 10, 25, 50, 75 and 100% of selected animals, respectively. The highest accuracies were in generation 23 for scenario 10% (0.31), in generation 37 for scenarios 25 (0.43), 50 (0.50) and 75% (0.55) and in generation 39 for 100% (0.59). Although increasing the density of phenotyped and genotyped animals increased prediction accuracy, some gains were marginal. These differences in accuracy must be contemplated in an economic framework to determine the cost-benefit of additional information.
89 Inclusion of GuarPro F-71 in a corn and soybean meal based diet: Effects on growth performance and nutrient metabolism in growing pigs
Authors: Shamimul Hasan M , Humphrey Rebecca M , Crenshaw Mark A , Brett James , Liao Shengfa F 
Published: July 2019

Abstract
Using alternative feedstuffs can be a feasible measure to reduce swine production cost. GuarPro F-71, a newly developed guar meal product, is considered as a potential protein source for pigs. This study was conducted to evaluate the effects of dietary GuarPro F-71 inclusion on growth performance and nutrient metabolism of growing pigs. Sixty crossbred barrows (31.9 ± 1.84 kg BW) were allotted to 5 dietary treatments according to a completely randomized experiment design with 4 pens/treatment and 3 pigs/pen. Diet 1 was a corn-and-soybean-meal based diet with nutrient composition following NRC (2012) recommendations. GuarPro-71 was used to replace 25%, 50%, 75%, and 100% of soybean meal (on equivalent CP basis) in Diet 1 to generate Diets 2, 3, 4, and 5, respectively. Crystalline amino acids were used to balance the essential amino acid concentrations across the 5 diets. Dietary inclusion of GuarPro-71 reduced ADFI (P < 0.01), whereas no clinical signs of unhealthiness of pigs were observed. The magnitude of ADFI reduction showed linear but also quadratic relationships (P < 0.05) with the GuarPro-71 inclusion rate. The blood plasma concentrations of six metabolites (urea nitrogen, total protein, albumin, glucose, total cholesterol, and total triglycerides) were not affected (P > 0.30), indicating that the pigs’ metabolic utilization of nutrients was not compromised. The cubic effect (P < 0.05) of dietary GuarPro-71 inclusion on the G:F suggests that the level of soybean meal replacement up to 75% by GuarPro-71 did not negatively affect feed efficiency in pigs. In short, the feed intake reduction due to the dietary GuarPro-71 inclusion should be, if not solely, responsible for the ADG and final BW reduction. Overall, this study suggests that the dietary inclusion of GuarPro-71 can negatively affect ADFI and ADG in growing pigs. The reason for the ADFI reduction warrants further investigation.
91 Effects of antibiotics on growth performance, diarrhea, and bacterial translocation in weanling pigs experimentally infected with a pathogenic E. coli
Authors: Kim Kwangwook , He Yijie , Jinno Cynthia , Yang Seijoo , Song Minho , Ji Peng , Liu Yanhong 
Published: July 2019

Abstract
The experiment was conducted to investigate the effects of antibiotics on growth performance, diarrhea, fecal β-hemolytic coliforms, and bacterial translocation of weaned pigs experimentally infected with F18 Escherichia coli (E. coli). Twenty-six pigs (6.88 ± 1.03 kg BW) were individually housed in disease containment rooms and randomly allotted to one of three treatments with 8–9 replicate pigs per treatment. The three dietary treatments were control diet and 2 additional diets supplemented with 0.5 or 50 mg/kg carbadox, respectively. The experiment lasted 18 d (7 d before and 11 d after first inoculation [d 0]). F18 E. coli inoculum was daily and orally as 1010 cfu/3 mL for 3 days. Growth performance was measured on d -7 to 0 before inoculation, and d 0 to 5 and 5 to 11 post-inoculation (PI). Diarrhea scores were daily checked throughout the experiment. Fecal samples were collected on d 2, 5, 8, and 11 PI to test the percentage of β-hemolytic coliforms in total coliforms. Bacterial translocation was measured in lymph nodes on d 5 and 11 PI. All data were analyzed by ANOVA using PROC MIXED of SAS. Pigs supplemented with high-dose of antibiotics had greater (P < 0.05) final BW and lower (P < 0.05) overall frequency of diarrhea, compared with pigs in control and low-dose antibiotics groups. Pigs supplemented with low-dose antibiotics had lowest (P < 0.05) ADG and feed efficiency from d 0 to 5 PI, and had highest (P < 0.05) percentage of β-hemolytic coliforms in fecal samples on d 2 and 5 PI, and greatest (P < 0.05) bacterial colonies in mesenteric lymph nodes on d 11 PI, compared with pigs in the other two groups. In conclusion, low dose antibiotic supplementation exacerbates the detrimental effects of E. coli infection on pig performance and diarrhea.
106 Cellular aquaculture and agriculture: a transformative solution for feeding our planet
Authors: Cooperhouse Lou 
Published: July 2019

Abstract
Lou Cooperhouse is President & CEO of BlueNalu, a company pioneering the category of cell-based seafood, and which has received the largest amount of seed funding globally in this category. Lou has his educational degrees in Food Science and Microbiology, and worked at ConAgra, Campbell’s Soup, and a Nestle-funded startup earlier in his career in a variety of leadership positions. He most recently served as Executive Director of the Rutgers University Food Innovation Center. During this presentation, Lou will provide an overview of cell-based seafood, meats, and poultry; why this will be a transformative and disruptive industry in the decades ahead; and the technical, marketing, and regulatory challenges that will be associated with its ultimate success.
120 Effects of dietary leucine concentration on branched-chain amino acid metabolism in growing pigs
Authors: Kwon Woong B , Touchette Kevin J , Simongiovanni Aude , Syriopoulos Kostas , Wessels Anna , Stein Hans H 
Published: July 2019

Abstract
The hypothesis that excess dietary Leu affects growth performance and metabolism of branched-chain amino acids (BCAA) in growing pigs was tested. Forty barrows (30.0 ± 2.7 kg) were placed in metabolism crates and randomly allotted to 5 diets that contained 100, 150, 200, 250, or 300% of the requirement for standardized ileal digestible Leu. Initial and final body weight of pigs and daily feed provisions were recorded. Urine and fecal samples were collected for 5 d to measure N balance and biological value of diets. At the conclusion of the experiment, blood, brain, liver, and muscle samples were collected and average daily gain (ADG), average daily feed intake (ADFI), and gain to feed ratio (G:F) were calculated. Orthogonal polynomial contrasts were used to determine linear and quadratic effects of increasing Leu in the diets. Results indicated that ADG, ADFI, and G:F decreased (linear, P < 0.05) as dietary Leu increased (Table 1). A trend (linear, P = 0.082) for decreased N retention and decreased (linear, P < 0.05) biological value of protein was also observed. Plasma urea N increased (linear, P < 0.05) and a quadratic reduction (P < 0.05) in plasma serotonin and a linear reduction (P < 0.05) in cerebral serotonin were observed with increasing dietary Leu. Concentrations of BCAA in liver increased (linear, P < 0.001), concentrations of BCAA in muscle decreased (linear, P < 0.05), concentration of α-keto-isovalerate was reduced (linear and quadratic, P < 0.001) in liver, muscle, and serum, and α-keto-β-methylvalerate was reduced (linear and quadratic, P < 0.001) in muscle and serum, whereas α-keto-isocaproate increased (linear, P < 0.05) in liver and muscle, and in serum (linear and quadratic, P < 0.001) with increasing dietary Leu. In conclusion, excess dietary Leu reduced growth performance and cerebral serotonin and tended to reduce protein synthesis.
133 Effect of a proprietary medium chain fatty acid blend on nursery pig performance
Authors: Mellick Dillon , De Souza Ana , Iseri Vanessa , Mani Venkatesh 
Published: July 2019

Abstract
Previous studies have shown that the inclusion of medium chain fatty acids (MCFA) results in an improvement in nursery pig performance. Therefore, the objective of this study was to evaluate a proprietary C8:C10 MCFA blend (CaptiSURE, Kemin Industries, Inc., Des Moines, IA) on nursery pig performance. A total of 360 weaned piglets (initial BW = 6.1 kg) were randomly assigned to a control (no MCFA blend) or 10 kg/t MCFA blend (10 pigs/pen, 18 replicate pens/treatment), in which MCFA blend was substituted at the expense of tallow at a 1:1 rate. Diets were manufactured in 3 dietary phases (d 0–7, 7–21, and 21–42) in pelleted form. Due to an unintended bacterial challenge at the sow farm, pigs were treated with amoxicillin using a pulse protocol (48 hrs on / 48 hrs off) from placement to d 21. Data were analyzed using the students T-test procedure, and pen served as the experimental unit. Within dietary phase 2 (d 7–21), the inclusion of MCFA blend improved ADG (264g vs 326g, P = 0.017) and G:F (0.79 vs 0.89, P = 0.005), while exhibiting a trend to improve ADFI (330g vs 364g, P = 0.080). Within dietary phase 3 (d 21–42), the inclusion of MCFA blend improved ADG (518g vs 581g, P = 0.024) and ADFI (719g vs 799g, P = 0.006). Overall (d 0–42), the inclusion of MCFA blend improved ADG (379g vs 438g, P = 0.007), ADFI (503g vs 0.562g, P = 0.009), and G:F (0.75 vs 0.78, P = 0.042), resulting in a 2 kg heavier pig (P = 0.043). In summary, the inclusion of a proprietary C8:C10 MCFA blend at 1.0% in nursery pig diets improved growth performance.
134 Evaluation of a medium chain fatty acid-based feed additive for nursery pigs
Authors: Thomas Lori L , Williams Hayden E , Woodworth Jason C , Tokach Mike D , Goodband Robert D , Dritz Steve S , DeRouchey Joel M , Mellick Dillon 
Published: July 2019

Abstract
A total of 350 pigs (DNA 400×200, initial BW=6.3 kg) were used in a 34-d growth trial to evaluate the effects of a medium chain fatty acid (MCFA)-based feed additive in nursery pig diets. Following arrival to the nursery facility, pigs were randomized to pens (5 pigs per pen) and allowed a 4-d acclimation period. Thereafter, pens of pigs were blocked by BW and randomized to 1 of 5 dietary treatments (14 pens per treatment). Treatments were a dose response of 0, 0.5, 1.0, or 2.0% MCFA-based additive (CaptiSURE, Kemin Industries, Inc.; Des Moines, IA) as well as a treatment including 1.0% MCFA from a 1:1:1 blend of C6, C8, and C10 (Sigma Aldrich, St. Louis, MO). Treatment diets were formulated and manufactured in two dietary phases (d 0 to 13 and 13 to 34). Data were analyzed as a randomized complete block design with pen serving as the experimental unit. Overall (d 0 to 34), increasing CaptiSURE increased (linear, P ≤ 0.014) ADG and ADFI. Feed efficiency improved (quadratic, P = 0.002) with increasing CaptiSURE up to 1% of the diet with no benefit thereafter. As a result of the linear improvement in ADG, pigs fed 2.0% CaptiSURE were 1.8 kg heavier (P = 0.05) than pigs fed diets without MCFA at d 34. There was no evidence for differences between pigs fed 1.0% CaptiSURE and pigs fed the 1.0% MCFA blend of C6, C8, and C10 in phase 1, phase 2 or in overall performance. In summary, the addition of up to 2% of this MCFA-based additive in nursery pig diets resulted in linear improvements in ADG and ADFI. The MCFA-based feed additive also resulted in a similar improvement in growth performance as the C6, C8, and C10 MCFA blend when both were added at 1% of the diet.