bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seasonal changes in the abundance and biomass of copepods in the south-eastern Baltic Sea in 2010 and 2011
Authors: Dzierzbicka-Glowacka Lidia , Lemieszek Anna , Kalarus Marcin , Griniene Evelina 
Published: September 2018

BackgroundCopepods are major secondary producers in the World Ocean. They represent an important link between phytoplankton, microzooplankton and higher trophic levels such as fish. They are an important source of food for many fish species but also a significant producer of detritus. In the terms of the role they play in the marine food web, it is important to know how environmental variability affects the population of copepods.MethodsThe study of the zooplankton community in the south-eastern Baltic Sea conducted during a 24-month survey (from January 2010 to November 2011) resulted in the identification of 24 invertebrate species (10 copepods, seven cladocerans, four rotifers, one ctenophore, one larvacean, and one amphipod). Data were collected at two stations located in the open sea waters of the Gulf of Gdansk: the Gdansk Deep (P1) (54°50′N, 19°19′E) and in the western, inner part of the Gulf of Gdansk (P2) (54°32′N, 18°48.2′E). The vertical hauls were carried out with the use of two kinds of plankton nets with a mesh size of 100 µm: a Copenhagen net (in 2010), and a WP-2 net (in 2011).ResultsThe paper describes the seasonal changes in the abundance and biomass of copepods, taking into account the main Baltic calanoid copepod taxa (Acartiaspp.,Temora longicornisandPseudocalanussp.). They have usually represented the main component of zooplankton. The average number of copepods at the P1 Station during the study period of 2010 was 3,913 ind m−3(SD 2,572) and their number ranged from 1,184 ind m−3(in winter) to 6,293 ind m−3(in spring). One year later, the average count of copepods was higher, at 11,723 ind m−3(SD 6,980), and it ranged from 2,351 ind m−3(in winter) to 18,307 ind m−3(in summer). Their average count at P2 Station in 2010 was 29,141 ind m−3, ranging from 3,330 ind m−3(in March) to 67,789 ind m−3(in May). The average count of copepods in 2011 was much lower at 17,883 ind m−3, and it ranged from 1,360 ind m−3(in April) to 39,559 ind m−3(in May).DiscussionThe environmental conditions of the pelagic habitat change in terms of both depth and distance from the shore. Although the qualitative (taxonomic) structure of zooplankton is almost identical to that of the coastal waters, the quantitative structure (abundance and biomass) changes quite significantly. The maximum values of zooplankton abundance and biomass were observed in the summer season, both in the Gdansk Deep and in the inner part of the Gulf of Gdansk. Copepods dominated in the composition of zooplankton for almost the entire time of the research duration. Quantitative composition of copepods at the P1 Station differed from the one at P2 Station due to the high abundance ofPseudocalanussp. which prefers colder, more saline waters.
Deep Level and Near‐Band‐Edge Recombination in Semiconducting Antiperovskite Hg3Se2I2 Single Crystals
Authors: Das Sanjib , McCall Kyle M. , Peters John A. , He Yihui , Kim Joon‐Il , Liu Zhifu , Kanatzidis Mercouri G. , Wessels Bruce W. 
Published: September 2018

AbstractThe wide‐bandgap, semiconducting ternary compound Hg3Se2I2 has shown promise as room‐temperature hard‐radiation detector. Since this compound was first reported, there has been significant improvement in crystal growth using a chemical vapor transport method with a polyethylene growth agent. To study the effects of this additional precursor on crystal quality, the nature of radiative and nonradiative defects using photoluminescence (PL) and photocurrent (PC) studies of Hg3Se2I2 single crystals are investigated. In contrast to earlier studies, excitation intensity‐dependence of PL emission shows that the near‐band‐edge (NBE) emission bands are all excitonic in nature. The PL intensity decreases with increasing temperature, with the higher energy peaks quenching by 40 K and the deeper levels quenched after 110 K. The PC spectra show a complex structure at room temperature related to NBE transitions in the band structure, while at low temperature only the direct gap transition is observed due to phonons freezing out. The PC spectra at low temperature also indicate several midgap levels that are attributed to native defects within the bulk crystal. These results indicate that the high quality of Hg3Se2I2 single crystals is maintained when the transport agent is used during growth, although there are still a variety of defects present.
Near‐Infrared Fluorescent Theranostic Cisplatin Prodrug with Transcatheter Intra‐Arterial Therapy: Application to Rabbit Hepatocellular Carcinoma
Authors: Li Qiang , Wang Qi , Wang Saibo , Zhu Shiqin , Yuan Tianwen , Guo Zhiqian , Cao Jun , Tian He , Zhu Wei‐Hong 
Published: September 2018

AbstractTranscatheter intra‐arterial therapy (TIT) has become valuable in the battle against primary and secondary hepatic malignancies. However, the lack of a mechanism to visualize real‐time drug release and avoid fast metabolic clearance of chemotherapeutic agents is the primary barrier to TIT for hepatocellular carcinoma. Here, a specific near‐infrared (NIR) fluorescent prodrug platform, that is, DSPE‐mPEG/DCM‐S‐Pt micelles (DCM‐S‐Pt@PEG), to assist TIT in direct administration to large mammals like rabbits, is presented. DCM‐S‐Pt@PEG consists of a NIR fluorophore for tracing drug release, a nonspecific antitumor drug cisplatin for hepatocellular carcinoma treatment, a glutathione‐activatable disulfide linker, and a DSPE‐mPEG nano‐micelle carrier for controllable drug release. DCM‐S‐Pt@PEG can make the drug accumulation in tumor tissues enhance the therapeutic effect by: i) specific delivery of prodrug to hepatic tumor tissues through the femoral artery by TIT, ii) sustained drug‐release from the biodegradable lipid DSPE‐mPEG micelle to minimize metabolic clearance, and iii) cancer biomarker–activated drug release. It provides a promising strategy to assist TIT in treating unresectable devastating hepatocellular carcinoma administration in the rabbit model, rather than common mouse model.
Robotic‐assisted surgery for rectal cancer: Current state and future perspective
Authors: Matsuyama Takatoshi , Kinugasa Yusuke , Nakajima Yasuaki , Kojima Kazuyuki 
Published: September 2018

AbstractInterest in minimally invasive surgery has increased in recent decades. Robotic‐assisted laparoscopic surgery (RALS) was introduced as the latest advance in minimally invasive surgery. RALS has the potential to provide better clinical outcomes in rectal cancer surgery, allowing for precise dissection in the narrow pelvic space. In addition, RALS represents an important advancement in surgical education with respect to use of the dual‐console robotic surgery system. Because the public health insurance systems in Japan have covered the cost of RALS for rectal cancer since April 2018, RALS has been attracting increasingly more attention. Although no overall robust evidence has yet shown that RALS is superior to laparoscopic or open surgery, the current evidence supports the notion that technically demanding subgroups (patients with obesity, male patients, and patients treated by extended procedures) may benefit from RALS. Technological innovation is a constantly evolving field. Several companies have been developing new robotic systems that incorporate new technology. This competition among companies in the development of such systems is anticipated to lead to further improvements in patient outcomes as well as drive down the cost of RALS, which is one main concern of this new technique.
Locally produced CD19 CAR T cells leading to clinical remissions in medullary and extramedullary relapsed acute lymphoblastic leukemia
Authors: Jacoby Elad , Bielorai Bella , Avigdor Abraham , Itzhaki Orit , Hutt Daphna , Nussboim Vered , Meir Amilia , Kubi Adva , Levy Michal , Zikich Dragoslav , Zeltzer Li‐at , Brezinger Karin , Schachter Jacob , Nagler Arnon , Besser Michal J. , Toren Amos 
Published: September 2018

AbstractAutologous CD19 chimeric‐antigen receptor (CAR) T cells demonstrated remarkable remission rates in relapsed and refractory acute lymphoblastic leukemia (R/R ALL). Here, we report results from a phase 1b/2 study of in‐house produced CD19 CAR with a CD28 costimulatory domain. Twenty‐one patients with R/R ALL were enrolled, and 20 infused. The median age was 11 years (range, 5‐48). Patients had a median of 4 prior regimens, including blinatumomab in 6 and prior stem–cell transplantation in 10. In total 8 patients had extramedullary (EM) leukemic involvement, and prior to lymphodepletion and CAR 7 had active lesions, a group underrepresented in previous trials. In vivo expansion of CAR T cells was observed in 18 patients. In total 16 patients developed cytokine release syndrome, and 11 patients developed neurotoxicity, with no toxic deaths. All responding patients were referred to an allogeneic hematopoietic stem‐cell transplantation. The remission rate was 90%, including resolution of all refractory EM sites. Four responding patients relapsed, 3 who had a PCR‐MRD positive remission at 28 days following CAR‐T cells and 1 patient 21 months after an MRD‐negative response. The estimated 1‐year event‐free survival and overall survival are 73% and 90%, respectively. Patients with R/R EM ALL may also benefit from CAR‐T cell therapy.
Internal corporate sustainability drivers: What evidence from family firms? A literature review and research agenda
Authors: Broccardo Laura , Truant Elisa , Zicari Adrian 
Published: September 2018

AbstractDespite the many studies on corporate sustainability, few have analyzed the specific case of the family business. Family firms have certain characteristics that make them different from nonfamily firms, making it valuable to analyze whether these peculiarities are also reflected in their attitude toward sustainability. Specifically, the determinants of the sustainability concept in family firms are unclear. Given the importance of family businesses in most economies, this paper will contribute to filling this gap, depicting through a literature review the main determinants that can affect the sustainability approach of the family firm. The systematic review was carried out through a documented process to guarantee its replicability. The findings show that drivers do not have a homogenous impact on sustainability initiatives due to the distinctiveness of these types of firms. This review contributes by systematizing the existing literature on such topics, identifying future research avenues, and providing several stimuli for researchers.
Attention deficit hyperactivity disorder symptoms and disordered eating in the English general population
Authors: Jacob Louis , Haro Josep Maria , Koyanagi Ai 
Published: September 2018

AbstractObjectiveAttention deficit hyperactivity disorder (ADHD) symptoms and eating problems often coexist, but many of the previous studies have not taken into account key variables which may be important in this association. Thus, the goal of this study was to assess the association between ADHD symptoms and disordered eating, while taking into account of a variety of factors.MethodThis study used cross‐sectional, nationally representative data from 7,403 people aged ≥16 years from England who participated in the 2007 Adult Psychiatric Morbidity Survey (APMS). ADHD symptoms were assessed with the Adult ADHD Self‐Report Scale (ASRS) Screener. Questions from the five‐item SCOFF screening instrument were used to identify possible ED. Multivariable logistic regression analyses were conducted.ResultsThe prevalence of possible eating disorder (ED) was much higher among those with ADHD symptoms (ASRS score ≥14) compared to those without ADHD symptoms (19.2 vs. 5.7%). ADHD symptoms were associated with possible ED (odds ratio [OR] = 3.48; 95% confidence interval [CI] = 2.56–4.72) after adjustment for age, sex, and ethnicity. After further adjustment for alcohol dependence, drug use, intelligence quotient, stressful life events, perceived stress, impulsivity, depression, anxiety disorder, and borderline personality disorder (BPD) traits, the OR was attenuated to 1.32 (95% CI = 0.82–2.13). Anxiety and BPD were the factors that led to the largest degree of attenuation.DiscussionA high prevalence of disordered eating in individuals with ADHD was observed. Factors such as co‐existing anxiety and BPD traits may be particularly important in this association. Future research should focus on the factors involved in the association between ADHD symptoms and disordered eating behavior.
Sulfur‐Tuned Graphene Networks as Pseudocapacitive Material for High Performance Supercapacitors
Authors: Wang Chaonan , Yang Yinye , Luo Shengyun , Ren Dasen , Yu Xu 
Published: September 2018

The construction of heteroatom sulfur‐doped graphene aerogel (HSG), with an interconnected structure, by a facile ice‐template method, combined with a thermal annealing treatment at 800 °C, is reported. The morphology and chemical nature of HSG are confirmed by several microscopic and spectroscopic analyses. The sulfur‐containing functional groups act as the electro‐active sites for the fast surface redox reaction. The specific capacitance of HSG is reached up to 367 F g−1 at a current density of 1 A g−1, whereas the specific capacitance of 272 F g−1 is maintained at a current density of 20 A g−1 with a capacitance retention rate of 74.1%. Particularly, the cyclic stability of HSG is close to 92% after 20 000 cycles at a current density of 5 A g−1. These excellent electrochemical behaviors of HSG can be attributed to the synergistic effects of the hierarchical structure and the formation of additional “pseudocapacitance” by heteroatom doping.
Insecticide-induced changes in amphibian brains: How sublethal concentrations of chlorpyrifos directly affect neurodevelopment
Authors: McClelland Sara J. , Bendis Randall J. , Relyea Rick A. , Woodley Sarah K. 
Published: September 2018

Abstract

Widespread use of pesticides often contaminates natural habitats, exposing nontarget organisms to pesticides that were designed to control pest populations. Even low levels of pesticides can affect aquatic communities both directly and indirectly. Previous work has shown that trace amounts of the pesticide chlorpyrifos altered tadpole morphology and neurodevelopment in artificial ponds (mesocosms). To determine whether effects resulted from direct chlorpyrifos exposure or from disruption of the food web due to a pesticide-induced decline in zooplankton, we examined the impacts of chlorpyrifos on amphibian development in the presence of chlorpyrifos-resistant zooplankton, a key component of the aquatic trophic community. Northern leopard frog (Lithobates pipiens) tadpoles were reared through metamorphosis in mesocosms containing either 0 or 1 µg/L chlorpyrifos and either chlorpyrifos-resistant or chlorpyrifos-sensitive Daphnia pulex zooplankton. Developmental exposure to chlorpyrifos resulted in metamorphs with a relatively wider optic tectum, medulla, and diencephalon compared with controls, and this result was found regardless of the zooplankton population within the mesocosm. Thus, chlorpyrifos directly impacted brain development, independent of the effects on the trophic community. With respect to body shape, chlorpyrifos had no effect on body shape of metamorphs reared in mesocosms with chlorpyrifos-sensitive zooplankton, but body shape was sensitive to zooplankton population in the absence of chlorpyrifos. To conclude, low, ecologically relevant doses of organophosphorous pesticides can directly impact neurodevelopment in a vertebrate model. Environ Toxicol Chem 2018;37:2692–2698. © 2018 SETAC
Self‐management recommendations for sickle cell disease: A Ghanaian health professionals' perspective
Authors: Druye Andrews , Robinson Brian , Nelson Katherine 
Published: September 2018

AbstractObjectiveTo describe self‐management recommendations for sickle cell disease (SCD) care among health professionals who manage SCD in Ghana.MethodNine health care professionals (nurses, doctors, and physician assistants) who work in SCD were interviewed. The semistructured interviews were recorded, transcribed, and analysed using the qualitative content analysis method. Self‐management recommendations were conceptualised as preventive health, self‐monitoring, self‐diagnosis, self‐treatment, and self‐evaluation.ResultsPreventive health recommendations were the commonest, where the professionals described similar topics including avoidance of cold temperature, frequent oral hydration, and healthy nutrition. Self‐monitoring recommendations included regular checks for pallor, urine colour, and splenic enlargement. Self‐diagnosis recommendations were captured as warning signs and included pain, fever, unusual feelings, and enlarged spleen. Pain and fever management were the focus of most self‐treatment advice, and there were some self‐treatment recommendations for dactylitis, anaemia, and priapism. There was considerable variation in the strategies recommended for the management of individual SCD‐related problems.ConclusionGhanaian health professionals involved in SCD care provide limited and inconsistent self‐management recommendations. There is a need for the development of SCD standards and guidelines that support effective self‐management. Health professionals working in SCD require continuing education in self‐management.
Outcome assessment for Brachial Plexus birth injury. Results from the iPluto world‐wide consensus survey
Authors: Pondaag Willem , Malessy Martijn J.A. 
Published: September 2018

ABSTRACTThere is no consensus regarding strategies to optimally treat children with a brachial plexus birth injury (BPBI). Comparison of outcome data presented by different centers is impossible due to the use of (1) many different outcome measures to evaluate results; (2) different follow‐up periods after interventions; and (3) different patient ages at the time of assessment. The goal of iPluto (international PLexus oUtcome sTudy grOup) was to define a standardized dataset which should be minimally collected to evaluate upper limb function in children with BPBI. This dataset must enable comparison of the treatment results of different centers if prospectively used. Three rounds of internet surveys were used to reach consensus on the dataset. A Delphi‐derived technique was applied using a nine point Likert scale. Consensus was defined as having attained a rating of 7/8/9 by > = 75% of the participants. A total of 59 participants from five continents participated in the Second and Third Rounds of the survey. Consensus was reached regarding four elements: (1) evaluation should take place at the age of 1/3/5/7 years; range of motion in degrees should be measured for (2) passive joint movement; (3) active range of motion; and (4) the Mallet score should be determined. Consensus on how to asses and report outcome for BPBI was only reached on motor items from the “Body Function and Structure” domain. Consensus regarding additional ICF domains to obtain a more elaborate set of outcome items, should be addressed in future research. © 2018 The Authors. Journal of Orthopaedic Research® Published by Wiley Periodicals, Inc. on behalf of the Orthopaedic Research Society. J Orthop Res 36:2533–2541, 2018.
Estimation of event‐based rainfall erosivity from radar after wildfire
Authors: Zhu Qinggaozi , Yang Xihua , Yu Bofu , Tulau Mitch , McInnes‐Clarke Sally , Nolan Rachael H. , Du Zheyuan , Yu Qiang 
Published: September 2018

AbstractRainfall erosivity impacts all stages of hillslope erosion processes and is an important factor (the ‘R factor’) in the Revised Universal Soil Loss Equation. It is estimated as the average annual value of the sum of all erosive events (EI30) over a period of many years. For each storm event, the EI30 value is the product of storm energy, E in MJ ha−1, and peak 30‐min rainfall intensity (I30, mm hr−1). Previous studies often focused on estimation of the R factor for prediction of mean annual or long‐term soil losses. However, many applications require EI30 values at much higher temporal resolution, such as postfire soil erosion monitoring, which requires a time step at storm events or on a daily basis. In this study, we explored the use of radar rainfall data to estimate the storm event‐based EI30 after a severe wildfire in Warrumbungle National Park in eastern Australia. The radar‐derived rainfall data were calibrated against 12 tipping bucket rain gauges across an area of 239 km2 and subsequently used to produce a time series of rainfall erosivity maps at daily intervals since the wildfire in January 2013. The radar‐derived daily rainfall showed good agreement with the gauge measurements (R2 > 0.70, Ec = 0.66). This study reveals great variation in EI30 values ranging from near zero to 826.76 MJ·mm·ha−1·hr−1 for a single storm event. We conclude that weather radar rainfall data can be used to derive timely EI30 and erosion information for fire incident management and erosion control. The methodology developed in this study is generic and thus readily applicable to other areas where weather radar data are available.
Impact of land degradation from mining activities on the sediment fluxes in two large rivers of French Guiana
Authors: Gallay Marjorie , Martinez Jean‐Michel , Allo Sébastien , Mora Abrahan , Cochonneau Gérard , Gardel Antoine , Doudou Jean‐Claude , Sarrazin Max , Chow‐Toun Franck , Laraque Alain 
Published: September 2018

AbstractWe analyzed two contrasting catchments located among the world's largest unspoiled tropical rainforests impacted by mining in the northeastern coastlands of South America. We used the following: (a) mining, agricultural, and urbanized areas to compare the land use evolution with suspended sediments and sediment yields; (b) field monthly river suspended sediments in the two catchments (2004–2015: n = 154); (c) MODIS remote sensing water color technique in the Maroni basin to complete (n = 387) and extend field suspended sediment sampling from 2000 to 2015; (d) hydroclimatic statistical analysis conditions and sediment concentrations to identify the long‐term trends, the abrupt changes in time series and to analyze if the environmental and anthropogenic factors control sediment yield regional variations. No significant long‐term changes were observed in precipitation or water discharge with the Mann–Kendall test. However, the mean suspended sediment concentration has increased significantly (239%) in the Maroni River with a breakpoint in 2009 and decreased (33%) in the Oyapock River (breakpoint in 2008). These differences are explained by the larger percentage of deforestation because of mining activities in the Maroni (0.37%) than in the Oyapock (0.06%) catchment. In the Maroni River, the increasing sediment yield trend (2000–2015) coincide significantly (r2 = 0.97; p < 0.0001) with the increase of 400% of mining areas, whereas no significant relationship with the runoff was found. In the Oyapock River, the runoff explains the sediment yield decreasing trend (r2 = 0.82; p < 0.0001) and no relationship with the land use change was found.