bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enduring Cognitive and Linguistic Deficits in Individuals With a History of Concussion
Authors: Stockbridge Melissa D. , Newman Rochelle 
Published: September 2019

PurposeThe purpose of this research is to determine whether individuals with a history of concussion retain enduring differences in narrative writing tasks, which necessitate rapid and complex integration of both cognitive and linguistic faculties.MethodParticipants aged 12–40 years old, who did or did not have a remote history of concussion, were recruited to take an online survey that included writing both a familiar and a novel narrative. They also were asked to complete multiple tasks targeting word-level and domain general cognitive skills, so that their performance could be interpreted across these dimensions.ResultsParticipants with a concussion history were largely similar to participants with no history of brain injury across tasks that targeted a single skill in isolation. However, participants with prior concussions demonstrated difficulty in providing both key content and details when presented with a novel video and asked to provide a summary of what they had just seen. Number of lifetime concussions predicted the inclusion of key content when summarizing the video. Thus, differences in cognitive and linguistic skills required for written narrative language may continue to be present far after concussion, despite average normative levels of performance on tasks targeting these skills in isolation.ConclusionsThese findings suggest that individuals with a concussion history, particularly a history of multiple concussions, may continue to experience difficulties for a long period after injury and are likely to benefit from more complex and ecologically valid assessment prior to discharge. Individuals with a concussion history who return to full participation in work, school, and recreational activities may continue to benefit from assistance when asked to rapidly acquire and distill novel information, as is often required in academic and professional environments.
Psychosocial Outcomes of Severe Traumatic Brain Injury in Relation to Discourse Recovery: A Longitudinal Study up to 1 Year Post-Injury
Authors: Elbourn Elise , Kenny Belinda , Power Emma , Togher Leanne 
Published: September 2019

Purpose
The interrelationship between psychosocial outcomes and discourse after severe traumatic brain injury remains largely unknown. This study examines outcomes relating to work, relationships, and independence within the context of discourse recovery across the 1st year post-injury.

Method

An inception cohort comprising 57 participants with severe traumatic brain injury was assessed at 3, 6, 9, and 12 months post-injury. Outcomes were measured with the Sydney Psychosocial Reintegration Scale–2 (
Tate et al., 2012
;
Tate, Simpson, Loo, & Lane-Brown, 2011
), and discourse was evaluated with Main Concept Analysis of a narrative retell. Correlation and linear regression analyses were utilized.

Results
Significant correlations were found between psychosocial outcomes reported by relatives and discourse performance across the 1st year. The 6-month discourse scores significantly predicted the 12-month psychosocial outcomes reported by relatives. Initial discourse severity and recovery pattern also informed outcomes.

Conclusions
Discourse disorders have a strong relationship with everyday outcomes relating to work, relationships, and independence as reported by relatives. Six months post-injury is a beneficial time for assessment, education, and service planning. Age, years of education, and aphasia may mediate recovery and outcomes. A clinical decision tree is offered to support goal setting.

Supplemental Material

https://doi.org/10.23641/asha.9755444
Network reliability framework integrating demand response and flexible OHL ratings
Authors: Abogaleela Mohamed , Kopsidas Konstantinos 
Published: September 2019

The need for flexible power networks has become an emerging challenge for network operators. The utilisation of emergency loadings and probabilistic thermal ratings for overhead lines (OHLs) are vital flexible options to the network operators. So far, the impact of the ageing risks associated with such OHLs operation on reliability and the operators’ managing actions to mitigate this impact, have not been thoroughly investigated. This study presents a novel methodology for optimising the available demand response in the network at emergency conditions for minimising the network ageing risks and network expected energy not supplied considering the criticality of an individual line's ageing. This methodology facilitates the analysis of the trade‐off between ageing and reliability. An index, defined as expected equivalent Line ageing, is also formed to quantify the network ageing; this associates the OHL ageing directly with the available demand response at the network busses. A case study on the IEEE RTS‐96 indicated a reduction on the network expected energy not supplied and expected interruption costs by almost 42 and 34%, respectively, while reducing the overall network ageing risk by 58%, enabling operators to extend the end‐of‐life of critical OHLs.
Infrared and sub-mm observations of outbursting young stars with Herschel and Spitzer
Authors: Postel A. , Audard M. , Vorobyov E. , Dionatos O. , Rab C. , Güdel M. 
Published: September 2019

Context. Episodic accretion plays an important role in the evolution of young stars. Although it has been under investigation for a long time, the origin of such episodic accretion events is not yet understood.
Aims. We investigate the dust and gas emission of a sample of young outbursting sources in the infrared to get a better understanding of their properties and circumstellar material, and we use the results in a further work to model the objects.
Methods. We used Herschel data, from our PI program of 12 objects and complemented with archival observations to obtain the spectral energy distributions (SEDs) and spectra of our targets. We report here the main characteristics of our sample, focussing on the SED properties and on the gas emission lines detected in the PACS and SPIRE spectra.
Results. The SEDs of our sample show the diversity of the outbursting sources, with several targets showing strong emission in the far-infrared from the embedded objects. Most of our targets reside in a complex environment, which we discuss in detail. We detected several atomic and molecular lines, in particular rotational CO emission from several transitions from J = 38−37 to J = 4−3. We constructed rotational diagrams for the CO lines, and derived in three domains of assumed local thermodynamic equilibrium (LTE) temperatures and column densities, ranging mainly between 0−100 K and 400−500 K. We confirm correlation in our sample between intense CO J = 16−15 emission and the column density of the warm domain of CO, N(warm). We notice a strong increase in luminosity of HH 381 IRS and a weaker increase for PP 13 S, which shows the beginning of an outburst.
Numerical models for the dust in RCW 120
Authors: Rodríguez-González A. , Meliani Z. , Sánchez-Cruces M. , Rivera-Ortiz P. R. , Castellanos-Ramírez A. 
Published: September 2019

Context. The interstellar bubble RCW 120 seen around a type O runaway star is driven by the stellar wind and the ionising radiation emitted by the star. The boundary between the stellar wind and interstellar medium (ISM) is associated with the arc-shaped mid-infrared dust emission around the star within the HII region.
Aims. We aim to investigate the arc-shaped bow shock in RCW 120 by means of numerical simulations, including the radiation, dust, HII region, and wind bubble.
Methods. We performed 3D radiation-hydrodynamic simulations including dust using the GUACHO code. Our model includes a detailed treatment of dust grains in the ISM and takes into account the drag forces between dust and gas and the effect of radiation pressure on the gas and dust. The dust is treated as a pressureless gas component. The simulation uses typical properties of RCW 120. We analyse five simulations to deduce the effect of the ionising radiation and dust on both the emission intensity and the shape of the shock.
Results. The interaction of the wind and the ionising radiation from a runaway star with the ISM forms an arc-shaped bow shock where the dust from the ISM accumulates in front of the moving star. Moreover, the dust forms a second small arc-shaped structure within the rarefied region at the back of the star inside the bubble. In order to obtain the decoupling between the gas and the dust, it is necessary to include the radiation-hydrodynamic equations together with the dust and the stellar motion. In this work all these elements are considered together, and we show that the decoupling between gas and dust obtained in the simulation is in agreement with the morphology of the infrared observations of RCW 120.
ADHS und hochfunktionale Autismus-Spektrum-Störungen
Authors: Schöttle Daniel , Schimmelmann Benno G. , van Elst Ludger Tebartz 
Published: September 2019

ZUSAMMENFASSUNGADHS und ASS sind früh beginnenden neuronale Entwicklungsstörungen, die häufig gemeinsam vorkommen. Sie haben anteilig eine gemeinsame genetische Grundlage, die sich sowohl in der Auftretenswahrscheinlichkeit beim selben Individuum als auch in den Familien der Betroffenen zeigt. Die Unterscheidung, um welche Störung es sich handelt oder ob diese als Komorbidität vorliegt, erfordert eine genaue diagnostische Längsschnittuntersuchung unter Einbeziehung von möglichst viel Fremdinformation. Die psychopharmakologische Behandlung der ADHS ist ähnlich wie beim alleinigen Vorliegen einer ADHS, allerdings sollten die eingesetzten Substanzen zunächst in deutlich niedrigerer Dosierung begonnen und nach Klinik gesteigert werden.
THADA_rs13429458 Minor Allele Increases the Risk of Polycystic Ovary Syndrome in Asian, but Not in Caucasian Women: A Systematic Review and Meta-Analysis
Authors: Park Sunmin , Liu Meiling , Zhang Ting 
Published: September 2019

AbstractPolycystic ovary syndrome (PCOS) is a highly prevalent disease in young women that also features increased insulin resistance. Genetic factors have a strong relationship with the etiology of PCOS. We assessed whether carrying THADA rs13429458 is associated with the development of PCOS by meta-analysis and whether the association is influenced by ethnicity. Articles were searched using PubMed, EMBASE, Cochrane Library, Korean scientific database, and Chinese and Indian medical databases to identify all eligible studies for evaluating the association of THADA rs13429458 and PCOS risk. The association was assessed in five genetic random effects models including the allelic (AG), recessive (RG), dominant (DG), homozygous (HMG), and heterozygous (HTG) genetic models. Subgroup analyses stratified by ethnicity (Asians and non-Asians) were assessed. Nine articles were selected and 1 association analysis of Korea PCOS study met Hardy–Weinberg equilibrium criteria. A set of 38 224 PCOS women and 120 173 healthy women were included. The AG and RG showed heterogeneity in the overall and Asian subjects, but the other genetic model did not exhibit heterogeneity in all subjects. AG, RG, DG, and HMG, but not HTG, exhibited publication bias in total subjects but there was no publication bias in all genetic models among Asians and non-Asians. The overall effect of THADA_rs13429458 on PCOS risk showed significant positive associations in pooling 10 studies. In sub-group analysis only Asians, but not non-Asians, had a positive association (AG: OR=1.24, p=0.001; RG: OR=1.32, p=0.002; DG: OR, 1.70, p<0.00001; HMG: OR, 1.71, p=0.002; HTG: OR=1.34, p=0,006). In conclusions, young Asian women with the minor allele (C) for THADA rs13429458 were at increased risk of PCOS.
Internationale Pflegekräfte in deutschen
Kliniken
Authors: Eßrich Marie-Luise , Wegmann Rita 
Published: September 2019

ZusammenfassungNicht erst durch den Pflegekräftemangel kommen auch aus dem Ausland Pflegekräfte
nach Deutschland, die auf den Intensivstationen der Kliniken eingesetzt werden.
Für die einen ist es eine Bereicherung, wie Marie-Luise Eßrich schreibt. Andere
bemängeln die unzureichenden Voraussetzungen, die internationale Pflegekräfte
oft mitbringen, gerade auch sprachlich, wie Rita Wegmann ausführt.
Flut, Fluch oder Segen?
Authors: Zoller Richard , Nositschka Jan 
Published: September 2019

ZusammenfassungWie nehmen Intensivpflegekräfte die Alarme auf der Intensivstation wahr? Werden
sie eher als hilfreich oder als störend empfunden? Sind es zu viele oder eher zu
wenige? Und verändert sich die Wahrnehmung ja nach Alter der Pflegekräfte? All
diesen Fragen ist das Autorenteam in einer Untersuchung auf den
Intensivstationen des Uniklinikums Bonn nachgegangen – mit teilweise
überraschenden Ergebnissen.
Interdisziplinäre Empfehlungen zur Behandlung des metastasierten Nierenzellkarzinoms
Authors: Miller Kurt , Bergmann Lothar , Doehn Christian , Gschwend Jürgen E. , Kuczyk Markus A. 
Published: September 2019

ZusammenfassungDie Prognose von Patienten mit metastasiertem Nierenzellkarzinom (mRCC) hat sich dank neuer Therapien deutlich verbessert. Überlebenszeiten von mehr als zwei Jahren sind realistisch. Immuntherapien mit Checkpoint-Inhibitoren haben das Therapiespektrum in der Erst- und Zweitlinientherapie erweitert.Sunitinib, Pazopanib, Tivozanib und die Kombination Bevacizumab + Interferon-alpha sind unabhängig vom Risikoscore für die Erstlinientherapie beim mRCC zugelassen. Für die Kombination Nivolumab + Ipilimumab sowie für Cabozantinib ist die Zulassung jeweils auf Patienten mit intermediärem und hohem Progressionsrisiko beschränkt. Die Immuntherapie war bez. des Gesamtüberlebens in dieser Subgruppe signifikant wirksamer als Sunitinib. Temsirolimus ist nur für Hochrisikopatienten zugelassen. Sunitinib und Pazopanib haben eine Zulassung auch für die Zweitlinientherapie – bei Pazopanib gilt diese für den Einsatz nach Zytokinen. Für Nivolumab und Cabozantinib wurde in der Zweitlinientherapie ein signifikanter Überlebensvorteil gegenüber Everolimus gezeigt. Die Kombination Lenvatinib + Everolimus sowie Axitinib sind weitere für die Zweitlinie zugelassene Substanzen. Everolimus als Monotherapie ist durch die neuen Optionen in der Zweitlinie abgelöst worden. Bei zunehmender Anzahl verfügbarer Therapien ist die Frage nach der optimalen Sequenztherapie weiterhin offen. Ziel eines interdisziplinären RCC-Expertengesprächs war es, gemeinsame Therapieempfehlungen auf Basis der aktuell publizierten Daten und der eigenen klinischen Erfahrung für den Praxisalltag abzuleiten. Die Ergebnisse werden in dieser Publikation vorgestellt.
Biologie als Schicksal? Kommentar zu „Wie viele
Geschlechter gibt es und kann man sie wechseln?“ aus wissenschafts- und
gesellschaftstheoretischer Perspektive
Authors: Bauer Robin 
Published: September 2019

ZusammenfassungDer Kommentar analysiert im ersten Teil das Wissenschaftsverständnis, das dem
Beitrag von Ponseti und Stirn (2019) zugrunde
liegt. Es wird entgegen dem Paradigma einer wertneutralen Wissenschaft
argumentiert, dass die Erzeugung wissenschaftlichen Wissens im
sozio-historischen und politischen Kontext gesehen werden muss, und dargelegt,
inwiefern der Beitrag von Ponseti und Stirn auch eine politische Intervention
darstellt. Der dem Artikel inhärente biologische Determinismus wird
problematisiert. Im zweiten Teil wird argumentiert, dass Trans*Identitäten nur
im gesellschaftlichen Kontext zu verstehen sind, vor allem in Bezug auf die
wirkmächtige Norm der Zweigeschlechtlichkeit sowie die institutionellen
Rahmenbedingungen eines Transitionsprozesses. Die Vielfalt der Strategien von
Trans*Personen im Umgang mit ihren nicht normkonformen Selbstbildern wird
Ponseti und Stirns Engführung aus der Begutachtungspraxis entgegengestellt.
Kommentar zu „Wie viele Geschlechter gibt es und kann man
sie wechseln?“ aus biologischer Perspektive
Authors: Voß Heinz-Jürgen 
Published: September 2019

ZusammenfassungAls promovierter Biologe gibt der Autor von „Making Sex Revisited: Dekonstruktion
des Geschlechts aus biologisch-medizinischer Perspektive“ (2010) einen Überblick
über die biologische Forschung zu Geschlecht. Unhinterfragte
Zweigeschlechtlichkeit wird als Gender-Ideologie dargelegt, indem eine
differenzierte biologische Sichtweise auf Geschlecht aufgezeigt wird. Auch wird
argumentiert, dass die Fortpflanzungsfähigkeit des Genitaltrakts nicht
lebensnotwendig ist, sodass Varianz hier ebenso möglich ist wie bei sexuellen
Lebensweisen.
Wie viele Geschlechter gibt es und kann man sie
wechseln?
Authors: Ponseti Jorge , Stirn Aglaja 
Published: September 2019

ZusammenfassungDie Aufteilung des Menschen in zwei Geschlechter wurde in jüngerer Vergangenheit
kritisiert, da es keine genaue Grenze zwischen beiden Geschlechtern gebe und
weil die Vorstellung von der Existenz zweier Geschlechter selbst das Ergebnis
eines sozialen Konstruktionsprozesses sei. Daher sei Geschlecht etwas, was eine
Person nur für sich bestimmen könne, folglich
Transsexualität/Geschlechtsdysphorie keine psychische Störung und die Ansprüche
der Betroffenen nach selbstbestimmter Wahl geschlechtsangleichender Maßnahmen
legitim.In der vorliegenden Arbeit wird die klassische Auffassung der
Zweigeschlechtlichkeit durch die Fortpflanzungsfunktion begründet. Die
Unterschiedlichkeit von Samen- und Eizelle (Anisogamie) hat weitreichende
Konsequenzen für die Lebenswirklichkeit des Menschen und begründet
geschlechtstypische Verhaltensneigungen und Geschlechtsrollen. Der aktuelle
Begriff Geschlechtsidentität wird kritisiert und einem anderen
Identitätskonzept, das therapeutische Anknüpfungspunkte bietet,
gegenübergestellt. Ferner wird erläutert, wie sich die Kritik am klassischen
Geschlechtsbegriff nachteilig für die Sexualwissenschaft sowie auch für die
Therapie geschlechtsdysphorischer Menschen auswirkt. Die Annahme, dass eine
Psychotherapie der Geschlechtsdysphorie unethisch ist, wird diskutiert und den
Ergebnissen neuerer Katamnesestudien gegenübergestellt. Unter Berücksichtigung
neurowissenschaftlicher Studien werden Vorschläge für eine neue
psychotherapeutische Strategie gemacht.
Comparison of Fluorine(18)-fluorodeoxyglucose and
Gallium(68)-citrate PET/CT in patients with tuberculosis
Authors: Ankrah Alfred O. , Lawal Ismaheel O. , Boshomane Tebatso M.G. , Klein Hans C. , Ebenhan Thomas , Dierckx Rudi A.J.O. , Vorster Mariza , Glaudemans Andor W.J.M. , Sathekge Mike M. 
Published: September 2019

Abstract
18F-FDG and 68Ga-citrate PET/CT have both been shown to be
useful in the management of tuberculosis (TB). We compared the abnormal PET
findings of 18F-FDG- and 68Ga-citrate-PET/CT in patients
with TB.
Methods Patients with TB on anti-TB therapy were included. Patients had a
set of PET scans consisting of both 18F-FDG and
68Ga-citrate. Abnormal lesions were identified, and the two sets of
scans were compared. The scan findings were correlated to the clinical data as
provided by the attending physician.
Results 46 PET/CT scans were performed in 18 patients, 11 (61 %) were
female, and the mean age was 35.7 ± 13.5 years. Five patients also had both
studies for follow-up reasons during the use of anti-TB therapy. Thirteen
patients were co-infected with HIV. 18F-FDG detected more lesions
than 68Ga-citrate (261 vs. 166, p < 0.0001).
68Ga-citrate showed a better definition of intracerebral lesions due
to the absence of tracer uptake in the brain. The mean SUVmax was higher for
18F-FDG compared to 68Ga-citrate (5.73 vs. 3.01,
p < 0.0001). We found a significant correlation between the SUVmax of lesions
that were determined by both tracers (r = 0.4968, p < 0.0001).
Conclusion Preliminary data shows 18F-FDG-PET detects more
abnormal lesions in TB compared to 68Ga-citrate. However,
68Ga-citrate has better lesion definition in the brain and is
therefore especially useful when intracranial TB is suspected.
Delayed Instrumentation Following Removal of Cranio-Vertebral Junction Chordomas: A Technical Note
Authors: Champagne Pierre-Olivier , Voormolen Eduard H. , Mammar Hamid , Bernat Anne-Laure , Krichen Walid , Penet Nicolas , Froelich Sébastien 
Published: September 2019

Abstract
Objective To investigate on the feasibility and safety of a new approach which consists of delaying instrumentation after destabilizing craniovertebral junction (CVJ) chordoma surgery, allowing proton beam radiotherapy to be performed in a metal-free tumoral cavity.
Design This is a retrospective series of a prospectively maintained database.
Participants Five consecutive patients operated on for a CVJ chordomas for which instrumentation after tumor resection was deferred to after radiotherapy treatment.
Main Outcome Measures The main outcome consisted of measurements of the following parameters: C0–C2 angle, atlanto-dens interval (ADI), condylar gap, and the position of the dens relative to McGregor's line and coronal inclination, performed at 3 different times for all patients: before tumor surgery (baseline), before instrumentation surgery, and after instrumentation surgery.
Results For all patients, CVJ parameters deteriorated during the delay period, but stayed within normal limits for most. Because of radiological instability, one patient necessitated instrumentation before receiving radiotherapy. All parameters except condylar gap were partially corrected after instrumentation. No new neurological symptom or evolving neck pain occurred during the delay period.
Conclusion Delayed instrumentation of CVJ chordomas can be a safe alternative that might lead to improved subsequent radiotherapeutical treatment. Patient's selection and close clinical and radiological follow-up are mandatory for the success of this approach.
Timing for Safe Return to Sport after Medial Patellofemoral Ligament Reconstruction: The Role of a Functional Test Battery
Authors: Matassi Fabrizio , Innocenti Matteo , Andrea Cozzi Lepri , Zanna Luigi , Malone Joseph , Civinini Roberto , Innocenti Massimo 
Published: September 2019

AbstractThe purpose of this article was to analyze clinical and functional results after medial patellofemoral ligament (MPFL) reconstruction and to establish if a computer-assisted physical test battery could determine a “safe timing” to return to sport. We hypothesized that “time-based” criteria to declare safe return to sport could not be reliable to predict functional recover. Fifty-eight young athletic patients were selected after isolated reconstruction of MPFL. The minimum follow-up was 8 months. All the patients were evaluated subjectively with Kujala and Short Form 36 (SF-36) scores and objectively through a standardized computer-assisted physical battery of seven tests (Back in Action, Corehab). No patient was lost at the end point of follow-up and no recurrence of patellar dislocation was reported. At 8 months, 31 patients (53.4%) returned to sport at preoperative levels, and 23 (39.6%) participated in sports at lower levels. The subjective evaluation reported an increase of Kujala (60–92.7) and SF-36 score (28.6/25.4–52.2/53.6). At computer-assisted objective assessment, only 23 patients (39.6%) fulfilled the criteria for safe return to sport, while 31 (53.4%) got an insufficient outcome and 4 (6.9%) failed to complete the test. From our data, clinical scores after MPFL reconstruction provide only little insight into return to sport. The introduction of a computer-assisted objective analysis in the decision-making process for proper return to sport is necessary to evaluate functional recovery and dynamic knee stability.