bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Clinical Assessment of Eccentric and Concentric Stepping Kinetics has Utility in Older African American Men with Knee Arthritis
Authors: Gonzales Tomas I. , Seamon Bryant A. , Boncella Katie L. , Hernandez Haniel J. , McIntosh Valerie , Blackman Marc R. , Harris-Love Michael O. 
Published: December 2024

Introduction:
Stair navigation is physically demanding for individuals with knee osteoarthritis
and may result in movement asymmetries that can be quantified using kinetic analysis
and force-time parameters. Thus, the purpose of this cross-sectional study was to determine if
kinetic force-time parameter asymmetries are present in individuals with knee osteoarthritis and
associated with functional outcomes.

Methods:
Forty-six older male veterans (61.6±5.6 years) participated. More and less involved
legs were defined using the Kellgren and Lawrence (KL) scale and self-reported pain. Kinetics
were measured with the Neurocom® Step Up and Over test and quantified with the lift-up index,
impact index, movement time, and stair-stepping smoothness. Smoothness was calculated from
the level of intermittency in acceleration and deceleration during the concentric and eccentric test
movements.

Results:
Smoothness was the only force-time parameter to demonstrate an asymmetry. Greater
smoothness values were observed for the less-involved leg (p<0.001, 95% CI: 1.22 to 3.64,
d=1.17) and were positively associated with gait speed (more-involved: r=0.47, p<0.01; lessinvolved:
r=0.53, p<0.01), Knee Injury and Osteoarthritis Outcome Score (KOOS) Symptom
(more-involved: r=0.31, p<0.05; less-involved: r=0.39, p<0.01) and ADL (more-involved:
r=0.32, p<0.05; less-involved: r=0.39, p<0.05) subscales, and isokinetic knee extension strength
(more-involved: r=0.31, p<0.05; less-involved: r=0.42, p<0.01).

Conclusion:
Stair-stepping smoothness was diminished in the more involved leg and was associated
with worse gait speed, patient-reported outcomes, and knee strength. This observation
may reflect compromised motor control associated with decreased strength and greater disease
severity in the more-involved leg.
Efficacy Assessment of Sulfated Flavanol Functionalized Silver Nanoparticles against MCF-7 Breast Cancer
Authors: Rajawat Shweta , Ramchandran B. , Malik M.M. 
Published: December 2024

Aim:
The present research work aims to formulate a cost-effective and less toxic drug
for specific and selective delivery at the tumor site.

Background:
Existing therapeutics, such as chemo, surgery, etc., for fast-paced MCF-7 breast
cancer, still face challenges, especially due to their toxic side effects. The unique properties of
metal nanoparticles embedded in anti-oxidant plant polymers have sparked great interest in the
formulation of less toxic-targeted drugs for cancer cure.

Objective:
The present work aims to synthesize a targeted formulation of colloidal nanosilver by
surface engineering of silver nanoparticles using plant polymers in electrolytic deposition technique,
developed indigenously at the institute lab.

Methods:
A current is passed through an elctrolyte, AgNO3, which splits it into ions. The positive
ions of Ag deposit over LDPE wrapped carbon cathode and negative ion, NO3, is liberated.
Ag+ ions get capped in-situ. These surface-modified silver nanoparticles formulate a colloidal
solution. UV-visible and FTIR spectroscopy, TEM-EDX, and XRD were used to validate asprepared
formulation and in vivo human tumor xenograft model in NOD-SCID mouse for efficacy
against MCF-7 breast cancer.

Results:
The as-synthesized formulation consists of pure spherical poly-dispersed silver nanoparticles
of average size 5.4 nm, coated with sulphated flavanols. The efficacy evaluation reported
that it significantly, T/C = 0.53, reduced tumor volumes with a 100% survival rate and change
in animal body weight <4 gms.

Conclusion:
The as-synthesized formulation can be used as a potential neo-adjuvant or adjuvant
drug along with existing therapeutics for MCF-7 breast cancer, significantly reducing the toxicity
and cost.
Enhancing Executive Function Skills in Children With Attention-Deficit/Hyperactivity Disorder via Immersive Virtual Reality Interventions: Scoping Review
Authors: Konaç Asli , Bini Maristella , Fusco Naomi , Bourdin-Kreitz Pierre 
Published: December 2024

Abstract

Background
This scoping review investigated immersive virtual reality (IVR) interventions for improving executive function skills of children and adolescents with attention-deficit/hyperactivity disorder (ADHD).

Objective
This study aimed to identify and closely inspect the characteristics of these interventions and provide a summary of key findings to guide researchers in their future investigations.

Methods
A search across Web of Science, Scopus, PubMed, and APA PsycInfo databases was carried out with restrictions of publication date (2000‐2023) and language (English). The inclusion criteria were (1) research articles, excluding protocols, book chapters, reviews, and meta-analyses; (2) usage of IVR, excluding computer-based VR or augmented reality technologies; (3) aim of targeting executive function skills; (4) sample of children and adolescents diagnosed with ADHD (with or without learning disorder comorbidity); and (5) intervention studies (quasi-experimental clinical trials and randomized controlled trials, excluding assessments). Finally, the characteristics of the studies were summarized and inspected.

Results
The search yielded 2484 potential records. After a rigorous screening process, 6 articles (5 randomized controlled trials and 1 pilot study) were included. A certain heterogeneity in duration, designs of IVR interventions, and outcome measures were observed. All studies reported overall improvements in the attentional performances of children; however, only a few reported improvements in executive functions. In addition, a tendency toward integration of neurofeedback systems with IVR technologies was observed.

Conclusions
Because of the specific objectives and related inclusion and exclusion criteria of this review, only a few interventions could be included and analyzed. Even though there seem to be promising applications of IVR for children and adolescents with ADHD, heterogeneity in intervention characteristics accompanied by observed overall high or serious risk of bias prevented the authors from making generalized conclusions.
Consistent and Correct Use of Condoms With Lubricants and Associated Factors Among Men Who Have Sex With Men from the Ghana Men’s Study II: Protocol for a Mixed Methods Study
Authors: Abdulai Ratif , Phalane Edith , Atuahene Kyeremeh , Phaswana-Mafuya Refilwe Nancy 
Published: December 2024

Background
Men who have sex with men (MSM) experience a disproportionate burden of HIV infection globally, including in Ghana. The use of condoms with lubricants correctly and consistently plays a vital role in reducing the number of new HIV infections among MSM. However, there are concerns about the consistent and correct use of condoms and lubricants among MSM in Ghana. In this regard, there is a need to understand context-specific factors associated with consistent and correct condom use with lubricants.

Objective
This study aims to determine the current scope of consistent and correct use of condoms with lubricants, associated factors, interventions, and user- and service-related challenges on correct condom and lubricant use among the MSM population in Ghana.

Methods
The study will use a mixed methods study approach. First, a retrospective analysis of the Ghana Men’s Study II data set involving 4095 MSM will be conducted to determine the scope of consistency and correct use of condoms with lubricants as well as associated factors. The data will be imported into STATA (version 17; StataCorp LLC) to treat missing data and outliers before the analysis. Bivariate and multivariate logistic regression analyses will be conducted to determine the associated factors of consistent condom use with lubricants. All statistical analyses will be done at a 95% CI, with significant differences at P<.05. Second, in-depth interviews with a purposive sample of about 15-20 stakeholders will also be conducted to understand contextual issues regarding the factors identified, identify existing interventions for correct condom and lubricant use, user and service-related challenges, and how best to address those challenges from the stakeholders’ perspectives. For qualitative data, thematic analysis will be conducted using Atlas.ti version 23.1.1.

Results
Qualitative and quantitative results will be triangulated together with systematic review results, and key findings will be highlighted and used to guide the development of a predictive model for improving correct and consistent condom use with lubrication among MSM. This protocol paper, part of a doctoral study by the first author (RA), received approval from the Research and Ethics Committee of the University of Johannesburg on May 10, 2024. Data collection commenced on August 20, 2024, and the expected results will be published by October 2025.

Conclusions
Results from qualitative interviews and secondary data analysis will be triangulated to develop a predictive model to strengthen the correct and consistent use of condoms with condom-compatible lubricants among MSM and other key population groups in Ghana and other parts of sub-Saharan Africa for future pandemic preparedness, policy making, and targeted budget allocation.

International Registered Report Identifier (IRRID)
DERR1-10.2196/63276
CORONAVÍRUS COMO PESSOA: PADRÕES SEMÂNTICO-SINTÁTICOS NAS METÁFORAS DO CORONAVÍRUS
Authors: Ribeiro Dionizio Alice , Maurílio de Melo Moura Heronides 
Published: December 2024

Este artigo apresenta reflexões inicias de uma pesquisa relacionada às metáforas do coronavírus. Os objetivos deste trabalho são: (i) refletir sobre a perspectiva ecológica da cognição e das metáforas; (ii) sistematizar estatisticamente as ocorrências metafóricas do termo <coronavírus> e <gripe> encontradas no jornal Folha de São Paulo (www.uol.folha.com.br) no período compreendido entre 10 de maio a 10 de junho de 2020; (iii) analisar e descrever instâncias de ocorrências metafóricas da categoria Pessoa e, por fim, (iv) relacionar a Teoria Ecológica da Metáfora à Gramática das Construções no estudo das metáforas sobre o coronavírus. O referencial teórico que dá suporte a esta pesquisa é a Teoria Ecológica da Metáfora (JENSEN; GREVE, 2019), (GIBBS, 2013), (GIBBS, 2012); a discussão sobre metáfora e doença (SONTAG, 2007), (NERLICH; HAMILTON; ROWE, 2002), (NERLICH; HALLIDAY, 2007); e as relações simbólicas (semântico-sintáticas) das metáforas a partir das construções e das valências verbais (PERINI, 2008), (GOLDBERG, 2019), (GOLDBERG; JACKENDOFF, 2004); (GOLDBERG, 1995). A metodologia utilizada nesta pesquisa pode ser sumarizada a partir dos seguintes passos: (i) procura ativa de artigos com menção ao termo <coronavírus> no site www.uol.folha.com.br no período de 10 de maio a 10 de junho de 2020; (ii) conversão dos artigos encontrados para o formato .txt; (iii) utilização do software AntConc para a sistematização quanti-qualitativa dos dados; (iv) sistematização dos dados a partir de tratamento estatístico; (v) busca ativa pelo termo <gripe> no mesmo período e conversão dos artigos em .txt; (vi) utilização do software AntConc para a sistematização quanti-qualitativa dos dados; e (vii) análise dos dados com base no referencial teórico escolhido. Os resultados apontam para a predominância da categoria Pessoa (79,09%) e, dentro dessa categoria, predomínio do veículo Inimigo de Guerra (61,35%), o que ressalta a frequência do processo de personificação do patógeno coronavírus.
Tecnologias Assistivas:
Authors: Mamede Maia Maria Vitória Campos , Pereira Raquel Alves 
Published: December 2024

A presente pesquisa objetiva analisar o papel da tecnologia assistiva (TA) no favorecimento da aprendizagem de crianças com síndrome de Asperger, a partir de entrevistas com profissionais do campo educacional. Tal análise utilizou como objeto de investigação um jogo eletrônico americano, denominado Gaining Face, que trabalha com o reconhecimento de expressões faciais para estas crianças. Pensar em inclusão de crianças com necessidades especiais, é pensar, antes de tudo, em conhecer esses indivíduos e o que os caracteriza. Além disso, a utilização de recursos que venha a favorecer esse processo é algo que precisa ser discutido. Dessa forma, as tecnologias assistivas, neste caso, os softwares educativos aparecem como alternativa pedagógica para aqueles que possuem tal transtorno. A avaliação dos entrevistados suscitou questionamentos quanto a mudanças na aparência (interface) e se a lógica de repetição da ferramenta contribuiria para a aprendizagem desses indivíduos. A identificação de características lúdicas foi um aspecto que gerou questionamentos na análise. Diante dos resultados, apareceram evidências da falta de capacitação do professor, o que se justifica pelo pouco conhecimento sobre a síndrome e de materiais tecnológicos direcionados à educação especial.
Desenvolvimento de um programa em Python para extração automatizada de dados na Biblioteca Cochrane: um estudo descritivo
Authors: Loeffel Noce Gobi Eduardo , Zucchi Paola , Leite Pacheco Rafael 
Published: December 2024

Introdução
A Biblioteca Cochrane é uma referência global no apoio à tomada de decisões em saúde englobando ensaios e respostas clínicas. A síntese de vários estudos científicos de qualidade, selecionados por critérios de inclusão e exclusão, torna possível a elaboração de uma revisão sistemática. Atualmente, os estudos publicados no Cochrane Database of Systematic Reviews (CDSR) são disponibilizados virtualmente através da internet, sendo o meio pelo qual pesquisadores buscam, avaliam e selecionam esses estudos, para a elaboração de uma revisão sistemática. Entretanto, um dos fatores que leva à demora na seleção de estudos é ter que abri-los um por um dentro das palavras-chave, o que potencializa uma seleção quantitativamente menor. O presente estudo propôs o desenvolvimento de um programa de computador capaz de navegar por todo o CDSR e exportar parágrafos e todos os outros elementos dos estudos em um banco de dados estruturado e direcionado ao pesquisador.
Métodos
O estudo foi conduzido no Núcleo de Avaliação de Tecnologias em Saúde (NATS) da Associação Paulista para o Desenvolvimento da Medicina (SPDM) e segmentado em duas partes, sendo a primeira o protótipo do programa de computador através de scripts nos navegadores Web e a última a consolidação do programa final, escrito na linguagem de programação Python e compatível com os principais sistemas operacionais do mercado.
Resultados
Como teste final, o programa de computador desenvolvido foi capaz de extrair todos os nove mil artigos presentes no CDSR e exportá-los num banco de dados preparado para ser visualizado com programas de planilhas, como o Microsoft Excel. Com o sucesso, o núcleo aprovou o programa.
Discussão e conclusões
O programa passou a ser utilizado como auxílio na seleção de estudos pelos pesquisadores do núcleo, os quais puderam solicitar as extrações com base em palavras-chave ou termos dispostos em quaisquer parágrafos dos textos dos estudos. A extração automática de todos os estudos presentes no CDSR levou cerca de um dia, sem requerer qualquer intervenção dos usuários, um tempo anteriormente tido como “impensável” pelos pesquisadores encarregados de fazer a busca manual dos estudos.
The omission of pumice prophylaxis on bracket failure rates after using self-etch primers: a randomised controlled clinical trial
Authors: Thevadass Kaminii , Zakaria Nor Nadia , Othman Siti Adibah 
Published: December 2024

Abstract

Objectives
To investigate orthodontic bond failure rates and the associated effectiveness of pumice prophylaxis as a preparatory step before applying self-etching primers (SEP).

Methods
Twenty participants with an average age of 23.9 years ± 5.13, were included in the trial. A total of 320 teeth were randomly assigned, using block randomisation in a 1:1 ratio (block of four), to either pumiced (n=160) or non-pumiced (n=160) quadrants. After preparation using SEP, the teeth were bonded with stainless steel brackets and monitored for bracket failure until a one-month period in a 0.019˝ × 0.025˝ stainless steel arch wire.

Results
The Fisher’s Exact Test and Chi-Square tests showed an overall bracket failure rate of 4.4%, with 1.8% in the pumiced and 2.5% in the non-pumiced group. The majority of bracket failures occurred on the 0.014˝ nickel titanium arch wire (71.4%) and an associated ARI score of one (57.1%). No significant difference was found in bracket failure rates between both groups related to the location, arch, ARI score or arch wire type (P>0.05).

Conclusions
Omitting pumice prophylaxis before applying SEP in orthodontic bonding does not lead to a higher bond failure rate, and factors like location, arch, ARI score, and arch wire type did not influence bracket failure in either group.
Effect of low frequency magnetic field (LFMF) on germination and vigour of accelerated aged radish (Raphanus sativus L.) seeds
Authors: Xia Xianzong , Zająс-Woźnialis Anna , Padula Gregorio , Kubisz Leszek , Hołubowicz Roman 
Published: December 2024

ABSTRACT
With the development of bio-magnetism, magnetic field (MF) treatment has been widely used in many fields, including Agriculture, Horticulture and Forestry. Among seed priming methods, the use of the MF treatment as a physical priming has the advantages of creating no pollution and allowing an easy operation. In this experiment, the low frequency magnetic field (LFMF) was generated by Viofor JPS Delux - a patented device adopted from human medical magnetic therapy. Seeds of radish (Raphanus sativus L.) cultivars Carmen (C) and Szkarłatna z Białym Końcem (SBK) were subjected to the routine accelerated aging (AA) procedure. Next, they were removed from the stress conditions, dried back to the standard moisture content level, and then treated with 10, 20 and 30 μT LFMF for 30, 60, 90 and 120 min., respectively. Afterwards, their seed quality was evaluated by germination and vigour tests. The results showed that LFMF treatment has improved the germination and vigour of the AA radish seeds. The optimal seed treatment conditions of the cultivars were different: for the cultivar C - 20 μT, 120 min. and for the cultivar SBK - 20 μT, 60 min. The quality of radish seeds and seedlings was also tested by a new method based on their ultra-weak photon emission during their germination and seedling growth. The received result could prove that LFMF treatment on AA seeds could have changed the metabolic processes responsible for germination and growth rate, but it had no harmful effect on the nature of their growth process.
ОСОБЛИВОСТІ СТРАТЕГУВАННЯ ІНКЛЮЗИВНОГО СЕРЕДОВИЩА ЗАКЛАДУ ОСВІТИ
Authors: Матвеєва Наталія 
Published: December 2024

У статті актуалізовано проблеми реалізації головної мети соціального розвитку на сучасному етапі – створення суспільства для всіх. Розкрито нормативно-правове підґрунтя, мету, зміст й складові стратегії формування інклюзивного освітнього середовища закладу, встановлено чинники впливу на його ефективність. Основна мета полягає у висвітленні місії та візії освітнього закладу з інклюзивним навчанням, змісту освіти, особливостей освітнього середовища, цінностей, стратегічних цілей і завдань у процесі стратегування. Проаналізовано напрями діяльності, виокремлено стрижневі принципи, визначено основні етапи створення та реалізації стратегії закладу освіти.
ОСОБЛИВОСТІ ФОРМУВАННЯ НАЦІОНАЛЬНОЇ І ГРОМАДЯНСЬКОЇ ІДЕНТИЧНОСТІ ПІД ЧАС ДИСТАНЦІЙНОГО І ЗМІШАНОГО НАВЧАННЯ У ПЕДАГОГІЧНОМУ УНІВЕРСИТЕТІ
Authors: Вітвіцький Вадим 
Published: December 2024

Автор у статті визначив окремі особливості формування національної і громадянської ідентичності студентів, які опановують освітні програми у педагогічному університеті. З опорою на фундаментальні напрацювання науковців Інституту проблем виховання Національної академії педагогічних наук України, узагальнення і поточні звіти про виховну роботу у Харківському національному педагогічному університеті імені Г.С. Сковороди автор виокремив такі особливості: необхідності неперервного розвитку критичного і системного мислення, когнітивних навичок студентів як основи свідомої національної і громадянської ідентичності; орієнтування на виклики і рішення безпеки спілкування і взаємодії під час дистанційного і змішаного навчання, органічного синтезу гуманістичних цінностей, імплементації дороговказів позитивних напрацювань країн Європейського Союзу з пріоритетним значенням культурних, духовних аксіологічних констант українського народу, культури студентських, професійних педагогічних спільнот у національному інформаційному просторі.
Bridas al Corazón Salvaje - Epistolario
Authors: Branda Luis 
Published: December 2024

El epistolario que se presenta es una continuación del que mantuvieron dos académicos, el Dr. Alberto Golding (bueno como el oro, pero potencialmente maleable) y la Dra. Manman Touchstone (comprueba si algo o alguien es genuino) (Branda, 2015). El título se inspira en la primera novela de Clarice Lispector, Perto do coração selvagem donde las relaciones humanas se examinan a través de los sentimientos de una mujer y donde la protagonista dice “No entanto como seria bom construir alguma coisa pura, liberta do falso amor sublimizado, liberta do medo de não amar... Medo de não amar, pior do que o medo de não ser amado...” (Lispector, 1995: 108).Los correspondientes en este epistolario intercalan sus sentimientos y reflexiones siendo el tema dominante el análisis de la naturaleza de las relaciones amorosas, incluyendo la de los padres a su progenie y la separación o el escoger un nuevo camino; “Não fugir, mas ir” (Lispector, 1995: 208)
«Неслучайный метр» в прозе В. Казакевича (на примере книги «За мной придет единорог»)
Authors: Кольцова Н.З. , Шестакова Ю.Ю. 
Published: December 2024

В статье анализируется роль стихового компонента в повествовательной организации книги. Устанавливается связь между музыкальным и стиховым началом, а также между метрикой и тематикой размера: метр, ассоциативно заряженный в ходе литературно-исторического бытования, входит в текст как готовая смысловая единица. Подтверждается, что вторжение метрических звеньев в прозаический строй текста носит не случайный, а вполне обоснованный характер.
The article focuses on the role of rhyme component in the narrative structure in V. Kazakevich’s «Unicorn will come for me». The correlation between musical and rhyme origins is revealed. There is also a connection revealed between meter’s pace and theme: the meter, associatively «charged» due to literary and social background, is included into the text as a completed semantic unit. The study also emphasizes that invasion of meter links into the prose context is not occasional but of a completely well-grounded nature.
Социолингвистический статус группы «русские переселенцы» в Германии
Authors: Гришина Д.Д. , Бирюкова Е.В. 
Published: December 2024

В статье рассматриваются лингвистические и социальные особенности группы русских переселенцев в Германии с учетом исторического фактора. Проводится анализ теоретической литературы по данному вопросу. Освещаются особенности языковой политики немецкого государства по отношению к мигрантам. Намечаются перспективы дальнейшего исследования.
The article deals with the linguistic and social peculiarities of Russian immigrants in Germany considering the historical factor. The theoretical literature on the issue being analyzed the article provides an overview of the sociolinguistic status of the group of immigrants under a common name «Russian immigrants». The features of the group language policy are highlighted. There are also prospects outlined for the further investigation.