bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Penerapan Metode Hiwar dalam Pembelajaran Bahasa Arab di Pondok Pesantren Tahfizh Yayasan Wakaf Surro Man Roa
Authors: Harun Ar Rasyid  , Nurainun Hasibuan  
Published: November 2024

Penelitian ini bertujuan untuk mengetahui dan menjelaskan penerapan metode hiwar yang dilakukan oleh guru pada pembelajaran bahasa Arab di Pondok Pesantren Yayasan Wakaf Surro Man Roa. Penelitian ini menggunakan jenis penelitian lapangan yang merupakan kualitatif dengan pendekatan deskriftif. Teknik pengumpulan data yang digunakan adalah observasi dan wawancara. Kemudian data dianalisis dengan model Miles and Huberman dan divalidasi menggunakan teknik Membercheck. Adapun hasil penelitian ini bahwa penerapan metode hiwar di Pondok Pesantren Yayasan Wakaf Surro Man Roa berjalan secara baik dengan adanya peran utama guru dalam memandu metode ini dan juga keaktifan siswa untuk mengikutinya dengan demikian metode hiwar di Pondok Pesantren Yayasan Wakaf Surro Man Roa berhasil menggambarkan keberhasilan pendekatan pembelajaran yang tidak hanya fokus pada bahasa Arab, melainkan juga dalam membentuk karakter dan keterampilan berfikir santri. Peran aktif ustadz sebagai fasilitator, termasuk memberikan motivasi, membimbing, mengatasi ketidakpastian, dan menciptakan suasana pembelajaran dinamis, menjadi kunci kesuksesan.
Controle de convencionalidade das leis
Authors: Dal Conte Tonial Maira Angélica , Piucco Micheli 
Published: November 2024

A Teoria do Controle de Convencionalidade das leis visa compatibilizar as normas internas com as normas internacionais, como se os ordenamentos formassem uma ordem harmônica e coerente. A teoria nasce na França, mas é no Sistema Interamericano de Direitos Humanos que ganha relevância internacional. Desde o ano de 2006, a Corte Interamericana de Direitos Humanos exige que os Estados Partes da Convenção Americana sobre Direitos Humanos e que se submetam a sua jurisdição, exerçam o controle de convencionalidade, compatibilizando suas normas à Convenção Americana e, à interpretação que dela realiza o Tribunal Interamericano. Diante disso, todos os julgamentos que esta Corte profere, devem ser analisados e compatibilizados internamente, independente se o Estado figurou ou não como sujeito na responsabilização internacional. Neste trabalho, o estudo versará sobre um caso de grande destaque internacional, que envolve direitos laborais, conhecido como o Caso de Lagos del Campo vs. Peru, e a possibilidade de manifestação da Corte na edição da Lei 13.467/2017. O presente trabalho utiliza o método indutivo para a realização da pesquisa e a técnica de pesquisa legal-bibliográfica, sendo utilizada análise de caso.
As audiências telepresenciais e a nova fronteira do acesso à justiça
Authors: Lopes Adriano Marcos Soriano , Santos Solainy Beltrão dos 
Published: November 2024

A audiência por videoconferência encontra previsão no ordenamento jurídico pátrio, tendo o Poder Judiciário regulamentado esse procedimento a fim de utilizá-lo de modo a evitar a interrupção da prestação jurisdicional em tempos de pandemia da Covid-19. O presente trabalho destina-se ao exame das audiências telepresenciais trabalhistas à luz do princípio do acesso à justiça, de modo a evidenciar se as condições para participar desse ato jurídico são acessíveis e de que forma superar eventuais obstáculos. Para tanto, a partir do método dedutivo, serão abordados, inicialmente, o tratamento doutrinário e legal das audiências telepresenciais trabalhistas, para, posteriormente, analisarem-se o substrato principiológico aplicável a esses atos jurídicos processuais e, por fim, o contexto emergencial em que as audiências virtuais foram adotadas para garantir a continuidade do exercício da jurisdição, bem como a acessibilidade do jurisdicionado a essa modalidade sob a ótica da ordem jurídica justa.
Epilepsy and genetic in Rett syndrome: A review
Authors: Operto Francesca Felicia , Mazza Roberta , Pastorino Grazia Maria Giovanna , Verrotti Alberto , Coppola Giangennaro 
Published: March 2019

AbstractIntroductionRett syndrome (RTT) is a severe X‐linked neurodevelopmental disorder that primarily affects girls, with an incidence of 1:10,000–20,000. The diagnosis is based on clinical features: an initial period of apparently normal development (ages 6–12 months) followed by a rapid decline with regression of acquired motor skills, loss of spoken language and purposeful hand use, onset of hand stereotypes, abnormal gait, and growth failure. The course of the disease, in its classical form, is characterized by four stages. Three different atypical variants of the disease have been defined. Epilepsy has been reported in 60%–80% of patients with RTT; it differs among the various phenotypes and genotypes and its severity is an important contributor to the clinical severity of the disease.MethodsIn this manuscript we reviewed literature on RTT, focusing on the different genetic entities, the correlation genotype–phenotype, and the peculiar epileptic phenotype associated to each of them.ResultsMutations in MECP2 gene, located on Xq28, account for 95% of typical RTT cases and 73.2% of atypical RTT. CDKL5 and FOXG1 are other genes identified as causative genes in atypical forms of RTT. In the last few years, a lot of new genes have been identified as causative genes for RTT phenotype.ConclusionsRecognizing clinical and EEG patterns in different RTT variants may be useful in diagnosis and management of these patients.
A case of adenomyoepithelioma with myoepithelial carcinoma of the breast
Authors: Ito Ryota , Ota Daisuke , Ando Sumiyo , Mori Masaya , Fukuuchi Atsushi 
Published: March 2019

Key Clinical MessageAdenomyoepithelioma with myoepithelial carcinoma of the breast is rare and diagnosed with histology and immunohistochemistry. We present a case of malignant transformation over 10 years, with ultrasonographic findings, highlighting the importance of an early excisional biopsy. Conservative surgery and radiation therapy were performed. There was no recurrence for 2 years.
Increased reliance of stream macroinvertebrates on terrestrial food sources linked to forest management intensity
Authors: Erdozain Maitane , Kidd Karen , Kreutzweiser David , Sibley Paul 
Published: March 2019

AbstractOur understanding of how forest management practices affect the relative importance of autochthonous vs. allochthonous resource use by headwater stream food webs is relatively poor. To address this, we used stable isotope (C, N, and H) analyses of food sources and macroinvertebrates from 15 streams in New Brunswick (Canada) and assessed how different catchment conditions arising from the gradient in forest management intensity affect the contribution of autochthonous resources to these food webs. Aquatic primary production contributed substantially to the biomass of invertebrates in these headwater streams, especially for scrapers and collector‐gatherers (25–75%). However, the contribution of algae to food webs decreased as forest management intensity (road density and associated sediments, water cations/carbon, and dissolved organic matter humification) increased, and as canopy openness decreased. This trend was probably due to an increase in the delivery of organic and inorganic terrestrial materials (dissolved and in suspension) in areas of greater harvesting intensity and road density, which resulted in more heterotrophic biofilms. Overall, results suggest that, despite the presence of riparian buffers, forest management can affect stream food web structure via changes in energy flows, and that increased protection should be directed at minimizing ground disturbance in areas with direct hydrological connection to streams and at reducing dissolved and particulate matter inputs from roads and stream crossings in catchments with high degrees of management activity.
Abdominal skeletal muscle mass as a predictor of mortality in Japanese patients undergoing left ventricular assist device implantation
Authors: Tsuji Masaki , Amiya Eisuke , Hatano Masaru , Nitta Daisuke , Maki Hisataka , Bujo Chie , Saito Akihito , Hosoya Yumiko , Minatsuki Shun , Hara Toru , Nemoto Mariko , Kagami Yukie , Endo Miyoko , Kimura Mitsutoshi , Kinoshita Osamu , Nawata Kan , Morita Hiroyuki , Ono Minoru , Komuro Issei 
Published: March 2019

AbstractAimsWe assessed preoperative muscle wasting in patients undergoing left ventricular assist device (LVAD) implantations using abdominal skeletal muscle images on computed tomography (CT) and explored the associations between the preoperative muscle wasting and clinical outcomes after LVAD implantation.Methods and resultsWe retrospectively examined the records of 111 patients who underwent continuous‐flow LVAD implantations as bridge‐to‐transplant therapy from January 2010 to December 2016 at our institution. After 33 patients were excluded, the study cohort consisted of 78 individuals. CT images used to calculate the skeletal muscle index (SMI) at the third lumbar vertebra level were obtained before the LVAD implantation procedures. Patients were classified as having muscle wasting if their SMI fell into the lowest gender‐based tertile. The median SMI for the study patients was 37.6 cm2/m2. The SMI cut‐off values for the lowest tertiles were 36.7 cm2/m2 for men and 28.2 cm2/m2 for women, resulting in 26 patients (33.3%) with muscle wasting in this study. During the mean follow‐up of 738 ± 379 days, there were 10 deaths (12.8% mortality). Seven of the 26 patients with muscle wasting (26.9%) died, and 3 of the 52 patients without muscle wasting (5.8%) died. The times to all‐cause mortality were significantly different between patients with and without muscle wasting (P = 0.0094). Muscle wasting was found to be associated with mortality in univariate and multivariate Cox analyses (hazard ratio: 4.32; 95% CI: 1.19–20.2).ConclusionsPreoperative muscle wasting was associated with a higher mortality in patients with LVAD. Assessment of the abdominal skeletal muscle area on CT prior to LVAD implantation can help predict mortality.
Age at Release, Size, and Maturation Status Influence Residualism in Hatchery Steelhead
Authors: Tatara Christopher P. , Larsen Donald A. , Cooper Matt R. , Swanson Penny , Middleton Mollie A. , Dickey Jon T. , Harstad Deborah , Humling Michael , Pasley Chris R. , Berejikian Barry 
Published: March 2019

Abstract
Steelhead Oncorhynchus mykiss that fail to emigrate seaward after release from hatcheries, commonly referred to as “residuals,” can have negative impacts on natural populations ranging from competition and predation to interbreeding with returning anadromous adults. We investigated how age at release, size, and maturation status influenced the rate of residual production in hatchery summer-run steelhead released from the Winthrop National Fish Hatchery (Methow River, Washington) between 2010 and 2015. Migration data from 21,598 individuals implanted with PIT tags identified 1,783 residual steelhead expressing two distinct phenotypes: immature male and female parr; and precociously mature males. We found that age at release significantly affected the predominant residual phenotype. Age-1 steelhead residuals (S1 rearing strategy) were dominated by smaller parr of both sexes (fish &lt; 146 mm FL), while age-2 residuals (S2 rearing strategy) were dominated by mature males, although both phenotypes were present in both S1 and S2 residual groups. Collections of residual steelhead in the Methow River indicated that parr phenotype residuals grew as well as natural-origin juvenile O. mykiss, suggesting potential competition for food resources and habitat. Detections of PIT tags within the Methow River basin indicated that precocious male residuals may overlap both spatially and temporally with previously documented spawning anadromous adults, posing a potential genetic management risk. Both residual phenotypes had poor overwinter survival, and only 1 of the 1,783 residual fish eventually returned to the Methow River as an anadromous adult. We conclude that the ecological and genetic consequences of residual steelhead far outweigh their potential contribution to anadromous production, and measures should be taken to reduce their production by changing hatchery rearing practices.
Influence of Left Atrial Appendage Amputation on Natriuretic Peptides—A Randomized Controlled Trial
Authors: Grieshaber Philippe , Arneth Borros , Steinsberger Ferdinand , Niemann Bernd , Oswald Irina , Renz Harald , Böning Andreas 
Published: March 2019

Background Closure or amputation of the left atrial appendage (LAA) is a common therapy for atrial fibrillation (AF). As the LAA is a hormone-producing organ, however, amputation is still somewhat controversial. We examined patients after surgical AF therapy with or without LAA amputation to determine the influence of LAA amputation on pro-atrial natriuretic peptide (proANP) and B-type natriuretic peptide (BNP) plasma levels and on clinical severity of heart failure.
Methods Twenty-one consecutive patients were prospectively randomized to either undergo LAA amputation (n = 10) or no LAA amputation (n = 11) between 05/2015 and 10/2015. All patients underwent coronary and/or valve surgery and concomitant AF surgery with either cryoablation (n = 3) or radio frequency ablation (n = 17). ProANP and BNP levels were measured preoperatively and until 800 days postoperatively.
Results Baseline proANP values were comparable between the groups (without LAA amputation: 4.2 ± 2.1 nmol/L, with LAA amputation: 5.6 ± 3.6 nmol/L). Postoperatively, proANP levels rose markedly in both groups. Even after LAA amputation, proANP levels remained elevated for 7 days postoperatively but fell to baseline levels at day 31 and remained on baseline level at 800 days postoperatively. ProANP levels in the LAA amputation group (5.8–9.7 nmol/L) were not significantly lower than in the group without LAA amputation (9.2–14.1 nmol/L; p = 0.357). BNP levels also rose after surgery in both groups until day 7. At 800 days after surgery, BNP levels were back at baseline levels in both groups. Clinical follow-up at 2 years postoperatively showed no difference in heart failure symptoms or need for heart failure medication between the groups.
Conclusion In contrast to commonly held beliefs about the endocrine and reservoir functions of the LAA, there seems to be no clinically relevant detrimental effect of LAA amputation on natriuretic peptide levels and severity of heart failure until up to 2 years postoperatively.
Dealing with dieback: forest manager attitudes towards developing resistant ash trees in the United Kingdom
Authors: Marzano Mariella , Woodcock Paul , Quine Christopher P 
Published: March 2019

AbstractEuropean ash (Fraxinus excelsior L.) is a highly valued native species in the UK and elsewhere. The rapid spread and predicted impact of ash dieback (caused by Hymenoscyphus fraxineus), has led researchers to explore a range of responses from introducing non-native ash to use of Genetic Modification (GM) technologies to develop disease resistance. To support decisions over which approaches should receive further investment to encourage adoption, it is necessary to understand what is acceptable to forest practitioners. Interviews with 22 forest advisors and managers revealed ash is highly valued for the multiple benefits it provides but past experiences with pest and diseases have encouraged a more cautious (‘wait and see’) attitude to approaches for dealing with ash dieback. These practitioners showed a strong interest in the concept of resistant ash but emphasized that any ‘new’ varieties should have similar characteristics, retain genetic diversity and be able to withstand future pests. There was limited support for planting non-native ash and use of GM methods and greater support for traditional breeding, though views varied dependent upon objectives and could evolve with experience countering the disease. There were concerns about the time required to produce resistant varieties and more information was needed about the costs, benefits and impacts of the different approaches. These findings point to the need for continued communication and engagement with stakeholders in the refinement of responses to dieback and any development of resistant ash.
Psychosocial information use for clinical decisions in diabetes care
Authors: Senteio Charles , Adler-Milstein Julia , Richardson Caroline , Veinot Tiffany 
Published: March 2019

AbstractObjectiveThere are increasing efforts to capture psychosocial information in outpatient care in order to enhance health equity. To advance clinical decision support systems (CDSS), this study investigated which psychosocial information clinicians value, who values it, and when and how clinicians use this information for clinical decision-making in outpatient type 2 diabetes care.Materials and MethodsThis mixed methods study involved physician interviews (n = 17) and a survey of physicians, nurse practitioners (NPs), and diabetes educators (n = 198). We used the grounded theory approach to analyze interview data and descriptive statistics and tests of difference by clinician type for survey data.ResultsParticipants viewed financial strain, mental health status, and life stressors as most important. NPs and diabetes educators perceived psychosocial information to be more important, and used it significantly more often for 1 decision, than did physicians. While some clinicians always used psychosocial information, others did so when patients were not doing well. Physicians used psychosocial information to judge patient capabilities, understanding, and needs; this informed assessment of the risks and the feasibility of options and patient needs. These assessments influenced 4 key clinical decisions.DiscussionTriggers for psychosocially informed CDSS should include psychosocial screening results, new or newly diagnosed patients, and changes in patient status. CDSS should support cost-sensitive medication prescribing, and psychosocially based assessment of hypoglycemia risk. Electronic health records should capture rationales for care that do not conform to guidelines for panel management. NPs and diabetes educators are key stakeholders in psychosocially informed CDSS.ConclusionFindings highlight opportunities for psychosocially informed CDSS—a vital next step for improving health equity.
Complications associated with combined surgical hip dislocation and periacetabular osteotomy for complex hip deformities
Authors: Edelstein Adam I , Duncan Stephen T , Akers Sean , Pashos Gail , Schoenecker Perry L , Clohisy John C 
Published: March 2019

AbstractSurgical hip dislocation (SD) and periacetabular osteotomy (PAO) are well-described treatments for femoroacetabular impingement (FAI) and acetabular dysplasia, respectively. Occasionally, complex deformities require a combined SD/PAO; the morbidity of performing both procedures in a single stage has not been fully investigated. We performed a retrospective review of a consecutive group of patients undergoing combined SD/PAO to investigate the incidence and character of perioperative complications. Forty-five patients (46 hips) were identified. Perioperative complications were graded by the modified Clindo-Davien complication scheme. Mean follow-up was 36 months (range 12–128), and no patients were lost to follow-up. Six complications occurred in six hips (13%). Four (8.7%) complications were minor (Grades I or II): one Brooker Grade III heterotopic ossification requiring no treatment, one superior pubic ramus nonunion requiring no treatment and two superficial wound infections requiring antibiotics. Two (4.3%) complications were major (Grades III or IV): one coxa saltans interna and labral tear requiring hip arthroscopy with labral repair and iliopsoas lengthening, and one deep surgical site infection requiring irrigation and debridement followed by development of arthritis requiring conversion to arthroplasty. The average Harris hip score improved from 62 ± 13 preoperatively to 80 ± 19 at final follow-up. Except for the single joint replacement, there were no long-term disabilities. There were no major neurovascular injuries, osteonecrosis, fractures or trochanteric nonunions. Combined SD/PAO for the treatment of complex, concomitant deformities of the proximal femur and acetabulum is associated with an acceptable risk of complications. The vast majority of complications that occurred were managed without permanent disability.Level of Evidence: IV
Relation ofHLA-DRB1to IgG4 autoantibody and cytokine production in muscle-specific tyrosine kinase myasthenia gravis (MuSK-MG)
Authors: Çebi M , Durmuş H , Yılmaz V , Yentür SP , Aysal F , Oflazer P , Parman Y , Deymeer F , Saruhan-Direskeneli G 
Published: March 2019

SummaryA small subset of myasthenia gravis (MG) patients develop autoantibodies against muscle-specific kinase (MuSK), which are predominantly of the immunoglobulin (Ig)G4 isotype. MuSK-MG is strongly associated with HLA-DRB1*14, HLA-DRB1*16 and HLA-DQB1*05. In this study, the possible effects of these HLA associations on MuSK IgG autoantibody or cytokine production were investigated. Samples from 80 MG patients with MuSK antibodies were studied. The disease-associated HLA types were screened in the DNA samples. The IgG1, IgG2, IgG3 and IgG4 titres of the MuSK antibodies and the levels of interleukin (IL)-4, IL-6, IL-17A and IL-10 were measured in the sera. Comparisons were made among the groups with or without HLA-DRB1*14, HLA-DRB1*16 or HLA-DQB1*05. The IgG4 titres of the MuSK antibodies were higher than those of the IgG1, IgG2 and IgG3 isotypes among the whole group of patients. DRB1*14 (+) DRB1*16 (–) patients had higher levels of IgG4 antibodies than those of DRB1*14 (–) DRB1*16 (+) patients. DRB1*14 (+) DRB1*16 (+) patients also had higher levels of IgG4 antibodies than those of DRB1*14 (–) DRB1*16 (+) and DRB1*14 (–) DRB1*16 (–) patients. Higher IL-10 and lower IL-17A levels were measured in DRB1*14 (+) DRB1*16 (–) patients than in DRB1*14 (–) DRB1*16 (–) patients. The higher IgG4 titres of MuSK autoantibodies in patients carrying HLA-DRB1*14 than those in the other patients suggest a role for HLA in the production of the antibodies. The differences in IL-10 and IL-17A support the role of DRB1 in the etiopathogenesis of this autoimmune response.
Tinea manuum: A report of 18 cases observed in the metropolitan area of Milan and review of the literature
Authors: Veraldi Stefano , Schianchi Rossana , Benzecry Valentina , Gorani Alberto 
Published: March 2019

SummaryObjectiveTinea manuum is considered in Italy as an uncommon infection, although no recent epidemiological data are available.MethodsIn the period 2000‐2018, we observed in the metropolitan area of Milan 18 patients with mycologically tinea manuum.ResultsThe infection was monolateral in all patients and characterised by erythema and scaling; in two patients, each vesicles and pustules were present. Two patients had also onychomycosis of one fingernail. No cases of simultaneous tinea pedis were observed. As far as the job of these patients is concerned, seven of them were masseurs, three barbers, two cattlemen, two masons, one car mechanic, one florist, one maid and one veterinarian. Trichophyton rubrum was isolated in 6 patients, Microsporum canis in 4, Trichophyton gypseum in 3, Trichophyton verrucosum in 3 and Trichophyton violaceum in 2 patients.ConclusionMasseurs were the most affected. Trichophyton rubrum and Microsporum canis were the most frequent isolated dermatophytes.