bluuebunny/crossref_metadata_2025_split huggingface dataset:
Length of stimulus presentation and visual angle are critical for efficient visual PER conditioning in the restrained honey bee,Apis mellifera
Authors: Lichtenstein Leonie , Lichtenstein Matthias , Spaethe Johannes 
Published: July 2018

ABSTRACTLearning visual cues is an essential capability of bees for vital behaviors such as orientation in space and recognition of nest sites, food sources and mating partners. To study learning and memory in bees under controlled conditions, the proboscis extension response (PER) provides a well-established behavioral paradigm. While many studies have used the PER paradigm to test olfactory learning in bees because of its robustness and reproducibility, studies on PER conditioning of visual stimuli are rare. In this study, we designed a new setup to test the learning performance of restrained honey bees and the impact of several parameters: stimulus presentation length, stimulus size (i.e. visual angle) and ambient illumination. Intact honey bee workers could successfully discriminate between two monochromatic lights when the color stimulus was presented for 4, 7 and 10 s before a sugar reward was offered, reaching similar performance levels to those for olfactory conditioning. However, bees did not learn at shorter presentation durations. Similar to free-flying honey bees, harnessed bees were able to associate a visual stimulus with a reward at small visual angles (5 deg) but failed to utilize the chromatic information to discriminate the learned stimulus from a novel color. Finally, ambient light had no effect on acquisition performance. We discuss possible reasons for the distinct differences between olfactory and visual PER conditioning.
Multiple Goals as Reference Points: One Failure Makes Everything Else Feel Worse
Authors: Weingarten Evan , Bhatia Sudeep , Mellers Barbara 
Published: July 2018

It is well known that goals serve as reference points, and their influence on pleasure can be understood with prospect theory’s value function. We examine how people feel about their progress on two goals (i.e., academics and fitness). What happens when they achieve one goal but fail to reach another? In four studies, we test the assumptions needed to explain hedonic reactions to progress along two goals. Loss aversion and diminishing sensitivity hold on each variable separately. However, we find violations of additivity in the integration of the emotions about outcomes. A success in one goal and a failure in another feel worse than the sum of the pleasure and pain associated with the gain and loss, respectively. The online appendix and data files are available at https://doi.org/10.1287/mnsc.2018.3097 . This paper was accepted by Elke Weber, judgment and decision making.
NOMENCLATURAL STUDY OF TETRASTIGMA LEUCOSTAPHYLUM AND TETRASTIGMA RAFFLESIAE (VITACEAE): TWO COMMON HOSTS OF RAFFLESIA IN SUMATRA
Authors: Rahayu Yeni , Chikamawati Tatik , Widjaja Elizabeth A. 
Published: July 2018

RAHAYU, Y., CHIKMAWATI, T. & WIDJAJA, E. A. 2018. Nomenclatural study of Tetrastigma leucostaphylum and Tetrastigma rafflesiae (Vitaceae): two common hosts of Rafflesia in Sumatra. Reinwardtia 17(1): 59–66. – A study of Tetrastigma (Miq.) Planch. (Vitaceae) conducted in Sumatra has revealed a number of species records. There are two species were misinterpreted. Two species names are here discussed: T. leucostaphylum (Dennst.) Alston ex Mabb. and T. rafflesiae (Miq.) Planch., which formerly united with T. lanceolarium.
Palladium and gold nanoparticles on carbon supports as highly efficient catalysts for effective removal of trichloroethylene
Authors: Meduri Kavita , Stauffer Candice , Qian Wen , Zietz Otto , Barnum Andrew , O’Brien Johnson Graham , Fan Dimin , Ji Weixiao , Zhang Changwen , Tratnyek Paul , Jiao Jun 
Published: July 2018

Abstract
PROGNOSTIC FACTORS FOR THE RESPONSE TO TOCILIZUMAB THERAPY IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS WITHOUT SYSTEMIC MANIFESTATIONS: A COHORT STUDY
Authors: Alexeeva Ekaterina I. , Dvoryakovskaya Tatyana M. , Isaeva Kseniya B. , Sleptsova Tatyana V. , Denisova Rina V. , Soloshenko Margarita A. , Lomakina Olga L. , Fetisova Anna N. , Rudnickaya Mariya G. , Vankova Dariya D. , Alshevskaya Alina A. , Moskalev Andrei V. , Mamutova Anna V. 
Published: July 2018

Background. To assign genetically engineered biologic drugs, we need data on the predictors for response to therapy. Prognostic factors for the response to tocilizumab in patients with juvenile idiopathic arthritis (JIA) without systemic symptoms are poorly studied.Objective. Our aim was to reveal early predictors for the response to tocilizumab therapy in patients with JIA without systemic symptoms.Methods. A retrospective cohort study enrolled patients with JIA without systemic symptoms who received tocilizumab therapy between July 2009 and August 2017. We assessed the association between the initial demographic, clinical, and laboratory parameters in patients and the best response (according to the ACR90 criteria) to treatment after a year.Results. The study included 95 (girls 85%) patients; the mean age was 10.3 (6.0; 13.6). During the first year of therapy, 71 (75%), 55 (58%), 38 (40%), and 22 (23%) patients achieved the improvement according to ACR30/50/70/90 criteria, respectively; 22 (23%) patients reached disease inactive stage according to the Wallace criteria. When performing multivariate analysis, the following improvement predictors were revealed based on the ACR90 criteria after a year of treatment: decrease in serum C-reactive protein level during the first month of therapy [odds ratio (OR) 1.024; 95% confidence interval (CI) 1.007–1.051], decrease in disease activity score on the visual analogue scale according to the parent/patient assessment (OR 1.048; 95% CI 1.005–1.105), early onset of the disease (OR 0.38; 95% CI 0.16–0.72), persistent oligoarthritis according to the ILAR (OR 9.9; 95% CI 1.5–109.3). During the first year of tocilizumab administration, neutropenia was registered in one patient, leukopenia — in three cases, and urticaria — in one case.Conclusion. The variant of JIA, the age at the disease onset, and the disease course pattern in the first month of tocilizumab therapy are the predictors of treatment efficacy throughout the year.
NUTRITION OF PRE-SCHOOL CHILDREN WITH OBESITY: A RETROSPECTIVE CROSS-SECTIONAL STUDY
Authors: Lir Darya N. , Novoselov Vladimir G. , Mishukova Tatiana A. 
Published: July 2018

Background.The prevalence of obesity in children continues to increase. The study of dietary habits of pre-school children allow to assess or establish the relationship between the dietary factor and obesity in this age group.Objective.Our aim was to determine the relationship between dietary habits and obesity in pre-school children.Methods.The study included pre-school children with primary exogenous obesity of the first degree and healthy children attending pre-school educational institutions. Based on the parent survey results, we determined the frequency of consumption of certain food groups, portion size (using the display material «Album of Meal and Food Portions»), the chemical composition, and energy value of diets (in the program «The Analysis of Human Nutritional Status»). The hygienic assessment of nutrition is performed in accordance with the age norms of physiological needs (NPNs) approved for the population of the Russian Federation.Results.The energy value and content of basic macronutrients of food rations for children with obesity (n = 40) were 45–58% higher than the NPNs. In the structure of the fat component of diets for children with obesity, saturated fatty acids predominated which caloric quota was significantly higher than in healthy children (n = 40). In healthy children with a normal energy value of diets, the total fat was 12% higher and the total carbohydrates was 12% lower than the NPNs. A general negative trend in a part of excess (2.5–4.4 times higher than the NPNs) consumption of mono- and disaccharides was revealed. The study revealed that obesity was associated with frequent (> 5 times/day) consumption of bakery products [odds ratio (OR) 6.7 (95% confidence interval (CI) 2.4–18.2], confectionery products (> 3 times/day) (OR 28.8; 95% CI 7.4–111.8), and products with a high fat content (mayonnaise, cream butter, etc. > 2 times/day) (OR 10.3; 95% CI 3.7–29.0).Conclusion.Obesity in pre-school children is associated with excessive and unbalanced nutrition with frequent consumption of bakery, confectionery, and high-fat foods.
Machine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma
Authors: Rosenberg Shai , Ducray Francois , Alentorn Agusti , Dehais Caroline , Elarouci Nabila , Kamoun Aurelie , Marie Yannick , Tanguy Marie-Laure , De Reynies Aurélien , Mokhtari Karima , Figarella-Branger Dominique , Delattre Jean-Yves , Idbaih Ahmed ,   POLA Network
Published: July 2018

Abstract

Background
1p/19q-codeleted anaplastic gliomas have variable clinical behavior. We have recently shown that the common 9p21.3 allelic loss is an independent prognostic factor in this tumor type. The aim of this study is to identify less frequent genomic copy number variations (CNVs) with clinical importance that may shed light on molecular oncogenesis of this tumor type.

Materials and Methods
A cohort of 197 patients with anaplastic oligodendroglioma was collected as part of the French POLA network. Clinical, pathological, and molecular information was recorded. CNV analysis was performed using single-nucleotide polymorphism arrays. Computational biology and feature selection based on the random forests method were used to identify CNV events associated with overall survival and other clinical-pathological variables.

Results
Recurrent chromosomal events were identified in chromosomes 4, 9, and 11. Forty-six focal amplification events and 22 focal deletion events were identified. Twenty-four focal CNV areas were associated with survival, and five of them were significantly associated with survival after multivariable analysis. Nine out of 24 CNV events were validated using an external cohort of The Cancer Genome Atlas. Five of the validated events contain a cancer-related gene or microRNA: CDKN2A deletion, SS18L1 amplification, RHOA/MIR191 copy-neutral loss of heterozygosity, FGFR3 amplification, and ARNT amplification. The CNV profile contributes to better survival prediction compared with clinical-based risk assessment.

Conclusion
Several recurrent CNV events, detected in anaplastic oligodendroglioma, enable better survival prediction. More importantly, they help in identifying potential genes for understanding oncogenesis and for personalized therapy.

Implications for Practice
Genomic analysis of 197 anaplastic oligodendroglioma tumors reveals recurrent somatic copy number variation areas that may help in understanding oncogenesis and target identification for precision medicine. A machine learning multivariable model built using this genomic information enables better survival prediction.
A incorporação das tecnologias digitais de informação e comunicação (TDIC) pelos professores de língua portuguesa das escolas estaduais de ensino médio de Linhares – ES
Authors: Vergna Márcia Aparecida , Silvia Antônio César Machado 
Published: July 2018

RESUMO: Este artigo objetiva investigar como está ocorrendo a incorporação das tecnologias digitais de informação e comunicação (TDIC), em especial o computador e a internet, na prática pedagógica dos professores de Língua Portuguesa do Ensino Médio da rede estadual de Linhares – ES. Para tal fim, realizou-se pesquisa de campo, utilizando o questionário como instrumento de coleta de dados. O público-alvo foram os alunos concluintes do Ensino Médio das escolas estaduais de Linhares – ES. Esta pesquisa é descritiva, de abordagem qualitativa. Os dados indicam que os professores de Língua Portuguesa, em sua maioria, não integram esses recursos em sua prática pedagógica. A principal finalidade dos que levam os alunos ao laboratório de informática é a realização de pesquisas, seguida, em menor proporção, pela preparação de slides para apresentação de trabalhos, digitação de textos, realização de leitura de obras literárias, envio de e-mail e exibição de vídeos relacionados ao conteúdo da disciplina. Espera-se que essa pesquisa possa ser usada como subsídio para nortear ações que visem ao melhor aproveitamento dos recursos disponibilizados pelas tecnologias digitais de informação e comunicação no espaço escolar, contribuindo também no direcionamento de políticas de formação inicial e continuada para o uso pedagógico dessas tecnologias.
PALAVRAS-CHAVE: incorporação; língua portuguesa; tecnologias digitais de informação e comunicação.

ABSTRACT: This article aims at investigating how the incorporation of digital information and communication technologies (TDIC), in particular the computer and the internet, is taking place in the pedagogic practice of Portuguese language teachers of Linhares-ES state network. For this purpose, a field research was performed using the questionnaire as a data collection instrument. The target audience was the high school graduating students from Linhares state schools-ES. This research is descriptive, of qualitative approach. The data indicate that most Portuguese language teachers do not integrate these resources into their pedagogical practice. Of those who take the students to the computer lab, the main use is for conducting some research, followed, in smaller numbers, to prepare slides for presentation of works, typing texts, reading literary works, sending an e-mail and display of videos related to the content of the course. It is hoped that this research can be used as a subsidy to guide actions aimed at making better uses of the resources available through the digital information and communication technologies in the school space, also contributing in the direction of initial and continued training policies for the pedagogical use of these technologies.
KEYWORDS: incorporation; Portuguese language; digital information and communication technologies.
Blogs educacionais não institucionais no processo de ensino-aprendizagem de língua portuguesa: uma revisão bibliográfica
Authors: Francisco Edmilson , Almeida Patrícia Vasconcelos 
Published: July 2018

RESUMO: O presente trabalho é resultado de um levantamento bibliográfico feito com amostras de trabalhos acadêmicos publicados e disponibilizados online de 2015 até o final do 1º semestre de 2017, sobre a temática da utilização dos blogs educacionais não institucionais no processo de ensino-aprendizagem de língua portuguesa. O resultado indica que a maioria das publicações trata do blog como ferramenta de ensino-aprendizagem e foi do tipo teórico-reflexiva. Em relação ao nível de ensino, a maior parte dos trabalhos se voltou para o Ensino Superior (graduação e pós-graduação) e para formação de professores da Educação Superior. O levantamento bibliográfico indicou que existem lacunas quanto à formação de professores de Educação Básica para uso do blog como ferramenta tecnológica no processo de ensino-aprendizagem. A análise dos estudos publicados apontou para a necessidade de realização de estudos que tragam experiências e relatos sobre o uso dos blogs para ensino-aprendizagem dos alunos e experiências de professores que os utilizam, na prática, como recurso tecnológico para formação de outros professores. O exame dos trabalhos acadêmicos revelou que existe carência de materiais didáticos que permitam que o(s) professor (es) se capacitem para o uso do blog como recurso tecnológico e estudos que o tratem como potente ambiente virtual de aprendizagem.
PALAVRAS-CHAVE: trabalhos acadêmicos;ferramenta tecnológica; educação.

ABSTRACT: The present work is the result of a bibliographical survey done with samples of academic papers published and made available online from 2015 until the end of the first semester of 2017, about the use of non-institutional educational blogs in the Portuguese language teaching-learning process. The result indicates that most publications treat the blog as a teaching-learning tool and was of a theoretical-reflexive type. Regarding the level of education, most of the work was focused on Higher Education (undergraduate and postgraduate) and for the training of Higher Education teachers. The bibliographic survey indicated that there are gaps regarding the formation of Basic Education teachers to use the blog as a technological tool in the teaching-learning process. The analysis of the published studies pointed to the need to carry out studies that bring experiences and reports about the use of blogs for teaching-learning of students and experiences of teachers who use, in practice, the blog as a technological resource for training other teachers. The examination of the academic work revealed that there is a shortage of didactic materials that allow the teacher(s) to be able to use the blog as a technological resource and studies that treat the blog as a powerful virtual learning environment.
KEYWORDS: academic work; technology tool; education.
Morde&Assopra – Zariguim e Naomi: o perigo da ausência de uma semiótica da face do robô humanoide
Authors: Sousa Vanda Maria 
Published: July 2018

RESUMO:A partir da narrativa, Morde&Assopra (REDE GLOBO, 2011), vamos considerar a representação do conceito de robô parceiro/amigo. A presente análise vai alavancar-se nas duas personagens robô amigáveis: Zariguim e Naomi. É nossa intenção clarificar que Morde&Assopra oferece representações de robôs humanoides, atualizando o mito de Pigmalião e, assim, fornecendo, na era digital, uma resposta à demanda arquetípica pela imortalidade. Recuperando para a discussão a relação homem/máquina ou homem/parceiro e considerando que tanto o robô Zariguim como a robô Naomi surgem como personagens humanizadas no texto em estudo, por esse fato, julgamos estar em condições de poder evidenciar a urgência e pertinência da análise semiótica da face dos robôs à semelhança da que se desenvolve para a face humana.
PALAVRAS-CHAVE: robô; narrativa transmedia; cross-media; semiótica; Morde&Assopra.

ABSTRACT:From the narrative, Morde&Assopra (REDE GLOBO, 2011), we will consider the representation of the robot concept partner / friend. The present analysis will leverage the two friendly robot characters: Zariguim and Naomi. It is our intention to clarify that Morde&Assopra offers representations of humanoid robots, updating the myth of Pygmalion and thus provide, in the digital age, a response to the archetypal demand for immortality. Recovering for the discussion the relationship man / machine or man / partner and considering that both the robot Zariguim and the robot Naomi appear as humanized characters in the study text, therefore, we believe we can show the urgency and relevance of the analysis semiotics of the face of robots, like that which has beingdeveloped for the human face.
KEYWORDS: robot; transmedia narrative; cross-media; semiotic; Morde&Assopra.
Tecnologias digitais, ação comunicativa e ética do discurso em redes sociais
Authors: Anecleto Úrsula Cunha 
Published: July 2018

RESUMO: As tecnologias digitais contribuíram para o surgimento de uma nova sociedade interconectada, favorecendo a criação de redes de comunicação, que ampliaram as participações do sujeito em diversos espaços públicos. Nesse sentido, a interação passou também a estruturar-se por nova ética e outras estéticas, que levassem em conta necessidades comunicativas das pessoas, suas lógicas argumentativas e pretensões de validade do discurso. Nessa perspectiva, este artigo tem como objetivo apresentar análise teórico-conceitual sobre a ética do discurso como fundamento para a ação comunicativa nas interações em redes sociais tecnológicas. Teoricamente, ancora-se nos estudos sobre racionalidade comunicativa, ética do discurso e esfera pública (HABERMAS, 1889, 1990, 2007, 2012), e redes sociais (RECUERO, 2009; ARAÚJO, 2016; PRIMO, 2005; FRANCO, 2012; BUZATO, 2016). Metodologicamente, apresenta-se a partir de uma análise hermenêutica, tendo como enfoque pressupostos interpretativo-críticos (HABERMAS, 1982, 2006, 2010). Como contribuição, o estudo aponta que a comunicação em rede, fundamentada em princípios éticos, proporciona ao sujeito participação em esferas públicas, de forma livre e democrática, alicerçadas no diálogo, na reestruturação dos papéis comunicativos e na emancipação discursiva, a partir da formação de uma identidade pós-convencional.
PALAVRAS-CHAVE: redes sociais; ação comunicativa; ética do discurso.

ABSTRACT: Digital technologies have contributed to the emergence of a new interconnected society, favouring the creation of communication networks, which extended the participation of the subject in various public spaces. In this sense, the interaction also happened to be structured from new ethics and other and aesthetics, which took into account people's communicative needs, their argumentative logics and pretensions of discourse validity. In this perspective, this article aims at presenting theoretical-conceptual analysis on discourse ethics as the basis for communicative action in the interactions through technological social networks. Theoretically, it is based in the studies on communicative rationality, discourse ethics and public sphere (HABERMAS, 1889, 1990, 2007, 2012), and social networks (ARAÚJO, 2009; ARAÚJO, 2016, PRIMO, 2005; FRANCO, 2012; BUZATO, 2016). Methodologically, it is based on a hermeneutical analysis, grounded on interpretative-critical assumptions (HABERMAS, 1982, 2006, 2010). As a contribution, the study points out that network communication, based on ethical principles, provides participation in public spheres, in a free and democratic way, based on dialogue, on the restructuring of communicative roles and on discursive emancipation, from the formation of a postconventional identity.
KEYWORDS: social networks; communicative action; ethics of the discourse.
Campo temático: possibilidade de organização de um dicionário infantil
Authors: Pereira Gonçalves Sheila de Carvalho 
Published: July 2018

RESUMO: Sabe-se que o processo de ensino-aprendizagem de língua na atualidade requer a inserção do aluno em práticas pedagógicas diversificadas, uma vez que a chamada era digital desencadeia uma série de mudanças na maneira de se construir o conhecimento. Nesse sentido, a utilização de novos recursos didáticos ganha espaço no contexto escolar, tais como os dicionários online. Este artigo tem por objetivo evidenciar a organização, a partir de campos temáticos, dos lexemas de nossa proposta de dicionário temático infantil online, DTI, em construção, especialmente desenvolvida para alunos que cursam do segundo ao quinto ano do ensino fundamental. A principal base teórica está alicerçada nos fundamentos da Lexicologia e da Lexicografia. Como resultado de nossas análises, defende-se que discussões dessa natureza podem contribuir com a criação e o aperfeiçoamento de obras cada vez mais funcionais, específicas e com um maior potencial para atender às necessidades de seu público-alvo.
PALAVRAS-CHAVE: lexicologia; lexicografia; campo temático; dicionário online.

ABSTRACT: It is known that the current process of teaching and learning language requires the insertion of the student in diverse pedagogical practices since the so-called digital era triggers a series of changes in the way we build knowledge. In this sense, the use of new didactic resources gains space in the school context, such as online dictionaries. This article aims at demonstrating the organization, from thematic fields, of the lexemes of our proposal for an online thematic children's dictionary, TCD, under construction, specially developed for students who study from the second to fifth years of elementary education. The main theoretical basis are the foundations of Lexicology and Lexicography. As a result of our analysis, it is argued that discussions of this nature can contribute to the creation and improvement of works that are increasingly functional, specific and with greater potential to meet the needs of their target audience.
KEYWORDS: lexicology, lexicography; thematic field; online dictionary.