bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anglicismos y galicismos en los orígenes de la lengua del boxeo
Authors: Ayuso Collantes Clara 
Published: July 2019

La lengua del boxeo se forma en España a principios del siglo XX, cuando este deporte echa a andar. Las noticias y crónicas deportivas aparecidas en los diarios de entonces —el madrileño ABC y el barcelonés El Mundo Deportivo— sirven de base para elaborar el corpus de anglicismos y galicismos que entraron en el primer tercio de siglo para nombrar conceptos técnicos y específicos de este deporte. Se considera el momento de penetración de estos neologismos, su uso y pervivencia. En este primer tercio de siglo fue cuando mayor número de extranjerismos penetraron, que posteriormente irían consolidándose, adaptándose o desapareciendo.
The language of boxing was formed in Spain in the early twentieth century, when this sport started up. The informations and the sport chronicles featured in the newspapers at the time, the madrilian ABC and The Mundo Deportivo of Barcelona, were the basis to elaborate the corpus of anglicisms and gallicisms which entered of the first third of the century to designate technical and specific concepts of this sport. It is considered the moment of incursion of these neologisms, its use and survival. It was in the first third of the century when a greater number of foreign expressions entered, which would later consolidate, adapt or disappear.
Tres dimensiones en el análisis de la variación de la (des)cortesía
Authors: Fernández García Francisco , Ortiz Viso Tinúviel 
Published: July 2019

El presente trabajo sostiene la conveniencia de que los estudios sobre la variación intercultural de la (des)cortesía no contemplen los entornos culturales analizados como bloques homogéneos y monolíticos, sino que tomen en consideración la variación interna a ellos inherente, tanto la de carácter social como la de carácter situacional. Desde este planteamiento, se analizan las características y conexiones entre las tres dimensiones de variación pragmática propuestas (cultural, social y situacional), para argumentar la idoneidad de un modelo de investigación que, sin renunciar a la formulación de patrones interculturalmente diferenciados, los genere de una forma dinámica, capaz de recoger los matices de variación dependientes de las variables sociales y situacionales.
The present paper argues that studies on intercultural variation of (im)politeness should not conceive the cultural environments analysed as homogeneous and monolithic blocks. On the contrary, these studies should take into account the internal variation inherent to those cultures, at both a social and a situational level. From this perspective, We analyse the characteristics and connections between the three dimensions of pragmatic variation (cultural, social and situational) that are proposed. Our aim is to ascertain the suitability of a research model which does not renounce the formulation of interculturally differentiated patterns, but which generates them in a dynamic way, being able to gather the nuances of variation which are dependent on social and situational variables.
Modelos lingüísticos y psicolingüísticos de la concordancia entre el sujeto y el verbo durante la producción: Una revisión
Authors: Sánchez María Elina 
Published: July 2019

Hablar es una de las actividades más naturales y frecuentes del ser humano. Sin embargo, supone coordinar con precisión temporal la intervención de materiales de naturaleza diversa. Al producir una oración, los hablantes deben transformar sus intenciones comunicativas en una secuencia de sonidos lingüísticos que permitan transmitir el mensaje que intentan comunicar. Esta transformación implica realizar una serie de operaciones complejas. Este trabajo se ocupa de una de esas operaciones, la concordancia, durante la producción de habla en tiempo real. Específicamente, se detallan los modelos lingüísticos y psicolingüísticos de la concordancia. En el primer apartado se describe cómo se efectúa la concordancia en español, para continuar con uno en el que se introduce cómo es vista la concordancia dentro del Modelo Minimalista de la Gramática Generativa. A continuación, se puntualiza cómo es el proceso de producción del lenguaje y los modelos que permiten explicar cómo se produce una oración sobre la marcha. Por último, se detallan diferentes modelos de producción de la concordancia.
Talking is one of the most natural and frequent activities of the human. However, it involves coordinating with temporary precision the intervention of materials of diverse nature. In producing a sentence, speakers must transform their communicative intentions into a sequence of linguistic sounds that allow them to convey the message they are trying to communicate. This transformation involves performing a series of complex operations. This work deals with one of these operations, the agreement, during online production. Specifically, the linguistic and psycholinguistic models of agreement are detailed. The first section describes how the agreement is performed in Spanish, to continue with a section that introduces how the agreement is seen within the Minimalist Model of Generative Grammar. Next, it is outlined how is the process of language production and models that allow to explain how a sentence is produced in real time. Finally, different models of agreement production are detailed.
Microbleed prevalence and burden in anticoagulant‐associated intracerebral bleed
Authors: Lioutas Vasileios‐Arsenios , Goyal Nitin , Katsanos Aristeidis H. , Krogias Christos , Zand Ramin , Sharma Vijay K. , Varelas Panayiotis , Malhotra Konark , Paciaroni Maurizio , Sharaf Aboubakar , Chang Jason , Kargiotis Odysseas , Pandhi Abhi , Schroeder Christoph , Tsantes Argyrios , Boviatsis Efstathios , Mehta Chandan , Mitsias Panayiotis D. , Selim Magdy H. , Alexandrov Andrei V. , Tsivgoulis Georgios 
Published: July 2019

AbstractPrior studies suggest an association between Vitamin K antagonists (VKA) and cerebral microbleeds (CMBs); less is known about nonvitamin K oral anticoagulants (NOACs). In this observational study we describe CMB profiles in a multicenter cohort of 89 anticoagulation‐related intracerebral hemorrhage (ICH) patients. CMB prevalence was 51% (52% in VKA‐ICH, 48% in NOAC‐ICH). NOAC‐ICH patients had lower median CMB count [2(IQR:1–3) vs. 7(4–11); P < 0.001]; ≥5 CMBs were less prevalent in NOAC‐ICH (4% vs. 31%, P = 0.006). This inverse association between NOAC exposure and high CMB count persisted in multivariable logistic regression models adjusting for potential confounders (OR 0.10, 95%CI: 0.01–0.83; P = 0.034).
Harnessing the Power of Stimuli‐Responsive Polymers for Actuation
Authors: Hu Liang , Wan Yu , Zhang Qiang , Serpe Michael J. 
Published: July 2019

AbstractA common behavior found in nature is the ability of plants and animals to naturally respond to their surroundings through actuation. Stimuli‐responsive polymers exhibit the same ability to naturally respond to changes in their environment, although manipulating them in a manner that allows their responses to be harnessed to do work via actuation is far from trivial. In this Review, examples that use temperature, pH, light, and electric field (and other) stimulation for actuation are highlighted. The actuation can result in materials that can be used to grip, lift, and move objects as well as for their own movement. As tremendous progress is being made in this research area, it is hard to imagine a future without these materials impacting lives in some way.
Biomodal Tumor‐Targeted and Redox‐Responsive Bi2Se3 Hollow Nanocubes for MSOT/CT Imaging Guided Synergistic Low‐Temperature Photothermal Radiotherapy
Authors: Song Yilin , Wang Yule , Zhu Yan , Cheng Yu , Wang Yidan , Wang Siyu , Tan Fengping , Lian Fan , Li Nan 
Published: July 2019

AbstractHyperthemia (>50 °C) induced heating damage of nearby normal organs and inflammatory diseases are the main challenges for photothermal therapy (PTT) of cancers. To overcome this limitation, a redox‐responsive biomodal tumor‐targeted nanoplatform is synthesized, which can achieve multispectral optoacoustic tomography/X‐ray computed tomography imaging‐guided low‐temperature photothermal‐radio combined therapy (PTT RT). In this study, Bi2Se3 hollow nanocubes (HNCs) are first fabricated based on a mild cation exchange way and Kirkendall effect and then modified with hyaluronic acid (HA) through redox‐cleavable linkage (‐s‐s‐), thus enabling the HNC to target cancer cells overexpressing CD‐44 and control the cargo release profile. Finally, gambogic acid (GA), a type of heat‐shock protein (HSP) inhibitor, which is vital to cells resisting heating‐caused damage is loaded, into Bi2Se3 HNC. Such HNC‐s‐s‐HA/GA under a mild NIR laser irradiation can induce efficient cancer cell apoptosis, achieving PTT under relatively low temperature (≈43 °C) with remarkable cancer cell damage efficiency. Furthermore, enhanced radiotherapy (RT) can also be experienced without depth limitation based on RT sensitizer Bi2Se3 HNC. This research designs a facile way to synthesize Bi2Se3 HNC‐s‐s‐HA/GA possessing theranostic functionality and cancer cells‐specific GSH, but also shows a low‐temperature PTT RT method to cure tumors in a minimally invasive and highly efficient way.
Antimonene Nanoflakes: Extraordinary Photoacoustic Performance for High‐Contrast Imaging of Small Volume Tumors
Authors: Yu Jingwen , Wang Xiu‐Hong , Feng Jinchao , Meng Xiaotong , Bu Xiangbao , Li Yang , Zhang Na , Wang Pu 
Published: July 2019

AbstractPhotoacoustic imaging (PAI) has evolved to a stage that high‐performance exogeneous contrast agents are urgently needed for imminent biomedical and clinical applications. Given that a material meets the basic criteria of efficient photoacoustic conversion, high biocompatibility, and fast excretion, great effort has been devoted to evaluating various materials for developing advantageous contrast agents to explore the full potentials of PAI. One focus is through modification of the current agents to boost their PA performance; whilst the other focus is to develop novel agents. Antimonene (AM) has emerged as a promising candidate for next generation of electronics among 2D materials due to its outstanding properties. Herein, it is reported that liquid‐phase exfoliated antimonene exhibits extraordinary photoacoustic performance, which is not only more advantageous than other 2D materials, such as black phosphorus, graphene oxide, and transition metal dichalcogenides, but also superior to the commonly used PA contrast agents, such as ICG and gold nanorods. An insight analysis reveals that the unique thermal property of AM, including intrinsic low thermal conductivity and the morphology‐related high interfacial thermal conductivity, might interpret the high photothermal conversion efficiency, and thus the excellent photoacoustic performance. The prodigious performance allows sensitive monitoring of intracellular events and high‐quality in vivo tumor imaging.
Ultrasonic‐Assisted Synthesis of Amorphous Polyelemental Hollow Nanoparticles as Efficient and Stable Bifunctional Electrocatalysts for Overall Water Splitting
Authors: Abdullah Muhammad Imran , Hameed Asima , Zhang Ning , Ma Mingming 
Published: July 2019

AbstractLarge‐scale electrolysis of water for hydrogen generation requires efficient, stable, and low‐cost electrocatalysts for oxygen evolution reaction (OER) and hydrogen evolution reaction (HER). Highly active and stable electrocatalysts can be achieved by amorphous materials with tunable polyelemental compositions, and further enhanced with proper nanostructures. Herein, the ultrasonic‐assisted template‐free synthesis of amorphous polyelemental (Co, Ni, Fe, W, B, P) hollow nanoparticles (PE‐HNP) is reported as an efficient and stable electrocatalyst for both OER and HER. For HER, as‐prepared PE‐HNP attains 1200 mA cm−2 current density at a low overpotential of 195 mV. For OER, PE‐HNP is in situ oxidized to form PEO‐HNP, which attains 1200 mA cm−2 current density at a low overpotential of 309 mV. The activities of PE‐HNP and PEO‐HNP remain unaffected after 20 h HER or OER test at high current densities, showing higher activity and stability than the benchmark electrocatalysts Pt/C and IrO2, respectively. The PEO‐HNP║PE‐HNP electrolyzer needs a 1.85 V cell voltage to drive a high current density of 400 mA cm−2, which is much better than the IrO2║Pt/C electrolyzer (2.15 V for 400 mA cm−2). The strategy provides a cost‐effective and convenient method to synthesize amorphous polyelemental materials with designed hollow nanostructures for the development of high‐performance electrocatalysts.
Intensity‐Dependent Metasurface with Digitally Reconfigurable Distribution of Nonlinearity
Authors: Luo Zhangjie , Wang Qiang , Zhang Xin Ge , Wu Jun Wei , Dai Jun Yan , Zhang Lei , Wu Hao Tian , Zhang Hao Chi , Ma Hui Feng , Cheng Qiang , Cui Tie Jun 
Published: July 2019

AbstractNonlinear metamaterials are of continuing interest by manipulating electromagnetic (EM) waves depending on incident intensity. Most of the existing nonlinear metamaterials rely on the interactions between superconcentrated EM fields and nonlinear substances within the resonant composites, which cannot be easily adjusted dynamically. Here, an intensity‐dependent metasurface is proposed, whose nonlinearity distribution is digitally reconfigurable. Different from previous works, an active microwave detecting circuit is integrated into each particle of the metasurface as the nonlinear module, endowing reflection phase of the particle with strong dependence on microwave intensities. By controlling the circuit using a digital bit, the particle can be switched to be linear with a fixed phase, which provides a digital way to reconfigure the arrangement of nonlinear and linear particles on the metasurface. Therefore, the phase profile on the surface is determined by the incoming intensity and digital controlling signals, opening up new possibilities in nonlinear EM wave manipulations. The concept is demonstrated by the digitally defined nonlinear scattering measurements at microwave frequencies. As a new metamaterial with the digitally reconfigurable nonlinearity and negligible thickness, this proposal may find potential applications including power protection, EM compatibility, nonlinear beam scanning, and so on.
Increasing phylogenetic stochasticity at high elevations on summits across a remote North American wilderness
Authors: Marx Hannah E. , Richards Melissa , Johnson Grahm M. , Tank David C. 
Published: July 2019

PremiseAt the intersection of ecology and evolutionary biology, community phylogenetics can provide insights into overarching biodiversity patterns, particularly in remote and understudied ecosystems. To understand community assembly of the high alpine flora in the Sawtooth National Forest, USA, we analyzed phylogenetic structure within and between nine summit communities.MethodsWe used high‐throughput sequencing to supplement existing data and infer a nearly completely sampled community phylogeny of the alpine vascular flora. We calculated mean nearest taxon distance (MNTD) and mean pairwise distance (MPD) to quantify phylogenetic divergence within summits, and assessed whether maximum elevation explains phylogenetic structure. To evaluate similarities between summits, we quantified phylogenetic turnover, taking into consideration microhabitats (talus vs. meadows).ResultsWe found different patterns of community phylogenetic structure within the six most species‐rich orders, but across all vascular plants phylogenetic structure was largely not different from random. There was a significant negative correlation between elevation and tree‐wide phylogenetic diversity (MPD) within summits: overdispersion degraded as elevation increased. Between summits, we found high phylogenetic turnover driven by greater niche heterogeneity on summits with alpine meadows.ConclusionsOur results provide further evidence that stochastic processes may also play an important role in the assembly of vascular plant communities in high alpine habitats at regional scales. However, order‐specific patterns suggest that adaptations are still important for assembly of specific sectors of the plant tree of life. Further studies quantifying functional diversity will be important in disentangling the interplay of eco‐evolutionary processes that likely shape broad community phylogenetic patterns in extreme environments.
Non‐high‐density lipoprotein cholesterol curves in Argentinean indigenous children living at high altitude and US children
Authors: Hirschler Valeria , Daniel González Claudio , Maccallini Gustavo , Hidalgo Mariana , Molinari Claudia ,   on behalf of the San Antonio de los Cobres Study Group Collaborators
Published: July 2019

AbstractObjectiveTo describe the non‐high‐density lipoprotein cholesterol (non‐HDL‐C) as mean and percentiles by age and sex in Argentinean indigenous schoolchildren living at 3750 m, contrasting these estimates with those reported in the 2011‐2012 National Center for Health Statistics reference population (NHANES).MethodsNon‐HDL‐C was calculated as total cholesterol‐HDL‐C. Analyses incorporated sampling weights for age and sex to obtain unbiased estimates. Sex‐ and age‐specific smoothed percentile curves were performed with Cole's LMS method.ResultsA total of 236 (49% males) children from San Antonio de los Cobres (SAC) were evaluated twice and compared with 1409 NHANES children. Non‐HDL‐C values were 4 mg/dL higher in SAC than in NHANES (109 vs 105 mg/dL, respectively). Trends in non‐HDL‐C 50th percentile in females differed between ages 6 to 7 and 8 years; in SAC non‐HDL‐C decreased from 111 to 104 mg/dL, NHANES levels remained stable from103 to 104 mg/dL. Among children aged 9 to10 years, non‐HDL‐C increased from 114 mg/dL to 117 mg/dL in SAC, but decreased from 113 to 107 mg/dL in NHANES. Between ages 12 and 13 years, non‐HDL‐C increased from 108 to 120 mg/dL in SAC, and remained steady from105 to 106 mg/dL in NHANES. The 50th percentile of non‐HDL‐C in males showed similar trends except for ages 6 to 7 to age 8 when non‐HDL‐C remained stable from 106 to 107 mg/dL in SAC, and increased from 98 mg/dL to 104 mg/dL in NHANES.ConclusionsNon‐HDL‐C levels in children vary with age, sex, ethnicity, and altitude. Different patterns in non‐HDL‐C were observed for girls in SAC compared with NHANES. However, more stable patterns were observed in boys in both groups.
PDGRFB mutation‐associated myofibromatosis: Response to targeted therapy with imatinib
Authors: Weller Johannes M. , Keil Vera C. , Gielen Gerrit H. , Herrlinger Ulrich , Schäfer Niklas 
Published: July 2019

AbstractHeterozygous activating mutations in platelet‐derived growth factor receptor B (PDGFRB) have been recently identified as a cause of autosomal‐dominant infantile myofibromatosis. We describe a 36‐year‐old man with PDGFRB c.1681C>T (p.R561C) mutation. Upon progressive disease, the patient received treatment with imatinib and showed a remarkable response with remission of multiple lesions after 12 months. This is the first report of an adult patient with PDGFRB c.1681C>T mutation treated with imatinib.
Biallelic variants in COX4I1 associated with a novel phenotype resembling Leigh syndrome with developmental regression, intellectual disability, and seizures
Authors: Pillai Nishitha R. , AlDhaheri Noura S. , Ghosh Rajarshi , Lim Jaehyung , Streff Haley , Nayak Anuranjita , Graham Brett H. , Hanchard Neil A. , Elsea Sarah H. , Scaglia Fernando 
Published: July 2019

AbstractAutosomal recessive COX4I1 deficiency has been previously reported in a single individual with a homozygous pathogenic variant in COX4I1, who presented with short stature, poor weight gain, dysmorphic features, and features of Fanconi anemia. COX4I1 encodes subunit 4, isoform 1 of cytochrome c oxidase. Cytochrome c oxidase is a respiratory chain enzyme that plays an important role in mitochondrial electron transport and reduces molecular oxygen to water leading to the formation of ATP. Defective production of cytochrome c oxidase leads to a variable phenotypic spectrum ranging from isolated myopathy to Leigh syndrome. Here, we describe two siblings, born to consanguineous parents, who presented with encephalopathy, developmental regression, hypotonia, pathognomonic brain imaging findings resembling Leigh‐syndrome, and a novel homozygous variant on COX4I1, expanding the known clinical phenotype associated with pathogenic variants in COX4I1.
Victims' emotional distress and preventive measures usage: Influence of crime severity, risk perception, and fear
Authors: Chadee Derek , Williams Diana , Bachew Raecho 
Published: July 2019

AbstractThe central thesis of this study is that crime victims' emotional distress, influenced by the severity of the offence experienced, impacts their propensity to utilize preventive measures via its influence on perceived risk of victimization and fear of crime. Path analysis was conducted to test a model of these relationships, utilizing data from a crime victimization survey conducted on the Caribbean Island, Trinidad, in 2015. Results suggest a direct predictive relationship between crime severity and emotional distress and indirect effects of emotional distress on preventive measures through risk perception and fear of crime. Findings were discussed in the context of prior research, comparability, and variances, and practical implications were noted.
Pristimerin Induces Autophagy‐Mediated Cell Death in K562 Cells through the ROS/JNK Signaling Pathway
Authors: Liu Yingxiang , Ren Ziting , Li Xiang , Zhong Jing , Bi Yun , Li Rui , Zhao Qun , Yu Xianjun 
Published: July 2019

AbstractChronic myeloid leukemia (CML) is a lethal malignancy, and the progress toward long‐term survival has stagnated in recent decades. Pristimerin, a quinone methide triterpenoid isolated from the Celastraceae and Hippocrateaceae families, is well‐known to exert potential anticancer activities. In this study, we investigated the effects and the mechanisms of action on CML. We found that pristimerin inhibited cell proliferation of K562 CML cells by causing G1 phase arrest. Furthermore, we demonstrated that pristimerin triggered autophagy and apoptosis. Intriguingly, pristimerin‐induced cell death was restored by an autophagy inhibitor, suggesting that autophagy is cross‐linked with pristimerin‐induced apoptosis. Further studies revealed that pristimerin could produce excessive reactive oxygen species (ROS), which then induce JNK activation. These findings provide clear evidence that pristimerin might be clinical benefit to patients with CML.
Ultra‐High to Ultra‐Low Drug‐Loaded Micelles: Probing Host–Guest Interactions by Fluorescence Spectroscopy
Authors: Lübtow Michael M. , Marciniak Henning , Schmiedel Alexander , Roos Markus , Lambert Christoph , Luxenhofer Robert 
Published: July 2019

AbstractPolymer micelles are an attractive means to solubilize water insoluble compounds such as drugs. Drug loading, formulations stability and control over drug release are crucial factors for drug‐loaded polymer micelles. The interactions between the polymeric host and the guest molecules are considered critical to control these factors but typically barely understood. Here, we compare two isomeric polymer micelles, one of which enables ultra‐high curcumin loading exceeding 50 wt.%, while the other allows a drug loading of only 25 wt.%. In the low capacity micelles, steady‐state fluorescence revealed a very unusual feature of curcumin fluorescence, a high energy emission at 510 nm. Time‐resolved fluorescence upconversion showed that the fluorescence life time of the corresponding species is too short in the high‐capacity micelles, preventing an observable emission in steady‐state. Therefore, contrary to common perception, stronger interactions between host and guest can be detrimental to the drug loading in polymer micelles.