bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lipid Class and Fatty Acid Compositions of Dried Sea Cucumber Apostichopus japonicus
Authors: Anisuzzaman Md , Jin Feng , Kabery Kamrunnahar , Jeong U-Cheol , Jung Hyun-Chol , Lee Sang-Ro , Kang Seok-Joong 
Published: August 2019

Introduction:
Sea cucumber, Apostichopus japonicus, is becoming popular around the world due to its nutritional and medicinal properties. There are still no detailed chemical studies of the lipid class, glycolipids compositions of sea cucumber.

Methods:
This study was conducted to determine the lipid class and glycolipid compositions of dried sea cucumber, A. japonicus, and analyze fatty acid compositions of Monogalactosyl Diglycerides (MGDG), Steryl Glycosides (SG) and Sulfoquinovosyl Diglycerides (SQDG). Total lipids of sea cucumber were extracted by Bligh and Dyer method and Sep-Pak Silica plus long cartridge, and Thin Layer Chromatography (TLC) silica gel G-60 F254 was used for the separation of different lipid classes and glycolipid compositions. The composition of fatty acids was analyzed by GC.

Results & Conclusion:
The level of total lipids in the dried sea cucumber, Apostichopus japonicus, was 4 ± 1% of dry weight (w/w) and the amount of neutral lipids, glycolipids and phospholipids was 31 ± 1%, 29 ± 1% and 40 ± 1% of the total lipids (w/w), respectively. MGDG, SG and SQDG were the major glycolipids, and the contents were 37.5 ± 0.3%, 33.8 ± 0.5% and 23.6 ± 0.7% of the total glycolipids (w/w), respectively and significantly higher than other glycolipids (p < 0.05). SQDG contained much higher Arachidonic Acid (AA), Eicosapentaenoic Acid (EPA) and MGDG contained higher Docosahexaenoic Acid (DHA) compared with SG (p < 0.05). Further investigation is required to understand the positional distribution of fatty acids and molecular species in MGDG, SG and SQDG in detail.
La cuestión moral en la obra de Maquiavelo. Un ensayo
Authors: Suárez Iñiguez Enrique 
Published: August 2019

<p>Este ensayo, señala el autor, se une a aquellos que han sostenido que algunas de las ideas de Maquiavelo son totalmente inaceptables desde el punto de vista moral, presentes en El Príncipe, como en los Discursos sobre la primera década de Tito Livio, entre otros escritos políticos menores y en sus despachos oficiales.</p>
PERANCANGAN INTERFACE APLIKASI E-SKRIPSI BERBASIS ANDROID
Authors: Mahara Rike , Basrul Basrul 
Published: August 2019

Skripsimerupakan suatu karya tulis ilmiah yang dibuat oleh mahasiswa sebagai tugas akhir untuk memperoleh gelar sarjana dari perguruan tinggi. Untuk membuat skripsi tentunya tidak mudah, mahasiswa harus terlebih dahulu mengajukan judul dari skripsi yang akan dikerjakan ke Program Studi. Selama ini pengajuan judul skripsi masih menggunakan media kertas dan mahasiswa harus mencari dan bertemu langsung dengan calon dosen pembimbing dari skripsi tersebut. Selain memerlukan waktu yang lama, mahasiswa perlu mengatur jadwal untuk bertemu dengan beberapa calon dosen pembimbing. Penelitian ini bertujuan untuk merancang suatu interface aplikasi yang dapat memudahkan mahasiswa dalam mengajukan judul skripsi secara online. Selain itu, mahasiswa dapat mengakses skripsi yang telah dikerjakan sebelumnya oleh mahasiswa lain, panduan penulisan skripsi, info tentang jadwal seminar proposal atau sidang, dan mengajukan beberapa calon pembimbing yan diminatinya. Rancangan interface aplikasi ini dibuat menggunakan Microsoft Office Power Point
A CASA DE EROS E DIONÍSIO - UM PROJETO DE ENSINO E ENCENAÇÃO
Authors: De Leão Raimundo Matos 
Published: August 2019

O ensaio reafirma temas sobre a modernização do teatro na Bahia. Esse processo se dá no interior da modernidade, movimento de expressão significativa no Brasil, durante o governo do presidente Juscelino Kubitschek. O moderno teatro na Bahia concretiza-se com a implantação da Escola de Teatro sob a direção de Eros Martim Gonçalves.
The Past, Present, and Future of Accounting History
Authors: Matthews Derek 
Published: August 2019

ABSTRACT
This paper seeks to establish statistically and explain the past, present, and likely future of accounting history. The article is based on a recently constructed database of publications in accounting history from 1989 to 2016. The data reveal that the output of accounting history articles grew very rapidly in the 1980s and 1990s attributed to the increased demand from the profession for accountancy teaching in universities, out of which emerged a relatively small number of accountancy academics who took an interest in history. From the turn of the millennium the output of articles has gone into a slow secular decline largely because the growth of accountancy teaching at universities has stalled. If the downward trend continues, the viability of the discipline is threatened. However, action might be taken at least to slow the “death rattle” of accounting history feared by Radcliffe; and some suggestions for doing so are made.
Wenetoklaks w leczeniu chorób układu krwiotwórczego i guzów litych
Authors: Kubiak-Mlonka Aleksandra , Ziółkowska Ewelina , Robak Tadeusz , Korycka-Wołowiec Anna 
Published: August 2019

StreszczenieWenetoklaks jest przedstawicielem nowej grupy leków, których mechanizm działania polega na zahamowaniu ekspresji antyapoptotycznych białek rodziny BCL-2. Białka te należą do głównych regulatorów wewnątrzpochodnego szlaku apoptozy i odgrywają kluczową rolę w patogenezie wielu chorób nowotworowych, w tym także nowotworów układu krwiotwórczego. Wyniki badań przedklinicznych i klinicznych wykazały, że wenetoklaks jest lekiem o wysokiej selektywności i akceptowalnym profilu bezpieczeństwa w przewlekłej białaczce limfocytowej (PBL). Jego duża skuteczność w eradykacji minimalnej choroby resztkowej wpływa na znaczne wydłużenie czasu przeżycia chorych. Lek w monoterapii jest przeznaczony do leczenia chorych z grupy wysokiego ryzyka z obecnością delecji 17p/ mutacji TP53 z oporną na leczenie i nawrotową PBL po wcześniejszym niepowodzeniu terapii inhibitorami szlaku sygnałowego BCR. Może być również stosowany u chorych bez del17p/ mutacji TP53, u których zarówno immunochemioterapia, jak i leczenie inhibitorem szlaku BCR okazało się nieskuteczne. Ponadto, wenetoklaks w skojarzeniu z rytuksymabem jest wskazany jako leczenie drugiej linii u chorych na PBL. Badania ostatnich lat wskazują, że wenetoklaks jest także skuteczny w leczeniu innych chorób hematologicznych, takich jak ostra białaczka szpikowa, szpiczak plazmocytowy, niektóre chłoniaki nie-Hodgkina oraz w terapii guzów litych.
Postępowanie w chłoniakach z obwodowych limfocytów T i NK
Authors: Czyż Jarosław 
Published: August 2019

StreszczenieChłoniaki z obwodowych komórek T i NK są należą do biologicznie i klinicznie zróżnicowanych grup chorób o złym prognozowaniu. Światowa Organizacja Zdrowia w swojej klasyfikacji podzieliła powyższe chłoniaki na pierwotnie rozsiane (białaczkowe), pierwotnie węzłowe, pierwotnie pozawęzłowe oraz pierwotnie skórne. Rzadkość występowania choroby oraz brak randomizowanych badań klinicznych powodują, że rekomendacje terapeutyczne opierają się na opisach małych grup pacjentów, badaniach 2. fazy oraz opiniach ekspertów. Schemat CHOP oraz jego kombinacje pozostają standardowym leczeniem pierwszego rzutu. Często stosowaną formą konsolidacji jest allogeniczny przeszczep szpiku. Poza tym pojawiło się szereg leków o nowatorskim mechanizmie działania. Należą do nich: pralatreksat, romidepsin, belinostat i brentuksymab wedotyny. Niestety, nie zmieniły one dramatycznie prognozowania w powyższych jednostkach chorobowych.
PATHOGENETIC TREATMENT OF ENZYMATIC PARAPANCREATITIS
Authors: Kulikov Dmitriy V. , Korolkov Andrey Y. , Morozov Victor P. , Vaganov Alexey A. 
Published: August 2019

Relevance. The most severe component of acute destructive pancreatitis (ADP) is enzymatic parapancreatitis (EPP). Pathogenetic treatment methods are limited.The objective was to evaluate the effectiveness of different treatment methods.Material and methods. Group 1 included 86 patients with ADP, enzymatic peritonitis (EP), EPP; 44 patients with EPP of them were performed LD of the retroperitoneal tissue. Group 2 included 120 patients with EPP without EP, 48 – with PPD (percutaneous drainage of parapancreatic tissue).Results. Mortality rate in patients with hemorrhagic EPP with LD was 16 %, without LD – 37 %, in patients with serous EPP with LD – 15 %, without LD –15 %. Mortality rate in patients with EPP without EP and with PPD was 6.2 %, without PPD – 8.3 %Conclusion. LD and PPD should have been applied on the basis of the variant of EPP.
EFFECT OF THE DRUG COATING CHARACTERISTICS ON VASCULAR REMODELING: COMPARING THE LATEST GENERATIONS OF STENTS
Authors: Trusov Ivan S. , Nifontov Evgeniy M. , Biryukov Alexey V. , Ivanchenko Roman D. , Dobrovolskiy Vadim V. 
Published: August 2019

The basic method of myocardial revascularization in acute coronary syndrome is coronary stenting. Due to the high risk of later coronary events such as restenosis and late coronary thrombosis, studies on the different types of stents are currently underway.The objective was to evaluate the degree of neointimal coverage of stents with a permanent and biodegradable polymer in one patient.The patient with unstable angina was implanted 2 everolimus-containing stents with a constant polymer (Promus Premier) and a biodegradable polymer (Synergy). After 9 months, optical coherence tomography (OCT) was performed with the calculation of indicators.774 struts of the Synergy and 701 struts of the Promus Premier were analyzed. When evaluating the thickness of the formed neointima, no significant differences was obtained (p=0.47). At the same time, a greater number of uncovered struts were detected in the Promus Premier stent compared with Synergy stent (1.14 vs. 0 %, p = 0.002). The number of malposed uncovered struts was not statistically different (0.14 versus 0.13, p = 1.00), the difference in the number of malposed struts covered approaches statistically significant (1.14 versus 0.26, p = 0.0545).According to the results of optical coherence tomography, no significant differences between the studied platforms was obtained when assessing the late lumen loss. A greater number of uncovered struts in the stent with permanent polymer was detected, which could be considered as a risk factor for the development of late coronary thrombosis.
South African Hydrostratigraphy: A conceptual framework
Authors: Diamond R. E. , Dippenaar M.A. , Adams S. 
Published: August 2019

Abstract
South African geology, geomorphology and climate are distinctly variable, resulting in a complex hydrological cycle superimposed on equally complex ground conditions. With fractured and karstic systems dominating the hydrogeology, thick vadose zones comprising soil and rock and at highly variable moisture conditions contribute to complex hydrostratigraphic systems comprising various confining and hydraulically connected units. This paper proposed standard terminology for basic concepts pertaining to the description of ground and water in the subsurface to eventually propose a hydrostratigraphic classification based on abiotic factors fairly constant over short periods of time (geology, geomorphology and climate), as well as those temporally highly variable (climate) and those introduced by human involvement (society). Ten major hydrostratigraphic units are eventually described, namely the Cape Fold Belt, Kalahari Desert, Witwatersrand Supergroup, Malmani Subgroup, Cenozoic Coastal Deposits, Saldanian Basement, Karoo Main Basin, Namaqua-Natal Metamorphics, Waterberg Group, and Archaean Granitoids.
Hydrogeological Properties of Gypseous soils in South Africa
Authors: Greyling M. , Van Rooy J.L. 
Published: August 2019

Abstract
Gypseous soils occur in the western arid and semi-arid regions of South Africa and Namibia. These soils exhibit a complex nature and abnormal behaviour due to their gypsum content and as such they have become more prevalent in research. As these soils are finding more use in industry, an astute understanding of their hydrogeological properties and behaviour is required. Powdery gypseous soil samples collected from the Northern Cape (Geelvloer) and Western Cape (Rooiberg and R355) Provinces, as well as a prepared sample, are subject to XRD analysis, particle size distribution determination and falling-head permeability tests using both water and brine. The testing served as preliminary research to guide further studies into the topic. The prepared sample, with 19% fines, comprises 35% gypsum and 65% sand. Geelvloer samples, with 91.95% gypsum content, are comprised mostly of sand-sized particles with 45% fines. Rooiberg samples contain 75% fines with a slightly lower gypsum content of 83.25%, while R355 samples have 50% fines with 75.35% gypsum. It is generally understood that particle size distribution contributes to the hydraulic conductivity of soils, where a higher portion fines will result in a lower conductivity. In the case of gypseous soils, the solubility is of importance as well, as it may have long term effects. With the intent of evaluating the effect of the aforementioned factors on the hydraulic conductivity of gypseous soils in South Africa, the samples taken represent differences in particle size distribution and origin. Geelvloer had k-values in the order of 8.82×10-6 m/s, with the brine sample giving 9.43×10-6 m/s, while the k-values for Rooiberg and R355 were in the order of 3.90×10-6 m/s and 5.87×10-6 m/s, respectively. The brine resulted in 5.63×10-6 m/s for Rooiberg and 9.90×10-6 m/s for the R355 sample. The made sample, having less fines, had k values in the order of 2.15×10-5 m/s, and 4.19×10-5 m/s for the brine. The differences between the results are largely negligible and show that despite what is believed to influence the hydraulic conductivity, in the case of gypseous soils in South Africa, on a small scale, it remained unaffected.
Examination of a Subgroup of Patients With Chronic Low Back Pain Likely to Benefit More From Pilates-Based Exercises Compared to an Educational Booklet
Authors: Amaral Diego Diulgeroglo Vicco , Miyamoto Gisela Cristiane , Franco Katherinne Ferro Moura , Dos Santos Franco Yuri Rafael , Bastos De Oliveira Naiane Teixeira , Hancock Mark Jonathan , Van Tulder Maurits W. , Nunes Cabral Cristina Maria 
Published: August 2019

Objective To investigate whether 2 previously published classification approaches, the updated treatment-based classification system and a Pilates subgroup defined by a preliminary clinical prediction rule, could identify patients with chronic low back pain who would benefit more from Pilates exercises compared to an educational booklet. Design Secondary analysis of a randomized controlled trial. Methods Two hundred twenty-two patients received advice and were randomly allocated to a group that received an educational booklet with no additional treatment (n = 74) or a group that received Pilates-based exercise treatment (n = 148) 2 or 3 times a week. At baseline, using a treatment-based classification system, patients were classified as having a good prognosis (positive movement control) or a poor prognosis. Similarly, using the Pilates clinical prediction rule, patients were classified as having a good prognosis (positive) or a poor prognosis (negative). The analysis was conducted using linear regression models to analyze the interaction between subgroup characteristics and treatment effect size, with changes in pain and disability from baseline to 6 weeks after randomization as dependent variables. Results None of the interaction terms for pain and disability were statistically significant. The treatment effect of Pilates versus an educational booklet was similar in all subgroups. Conclusion The treatment-based classification system and the Pilates clinical prediction rule did not differentiate subgroups of patients with chronic low back pain who were more or less likely to benefit more from Pilates compared to an educational booklet. J Orthop Sports Phys Ther 2020;50(4):189–197. Epub 23 Aug 2019. doi:10.2519/jospt.2019.8839
HAK DAN KEWAJIBAN SEBAGAI DASAR NILAI INTRINSIK WARGA NEGARA DALAM MEMBENTUK MASYARAKAT SIPIL
Authors: Rahmandani Fahdian , Samsuri Samsuri 
Published: August 2019

Rights and obligations are one of the important elements that need to be cared for by the state. In the context of citizenship, rights and obligations become intrinsically basic values of citizens in building a civil society. Almost everyone has understood between rights and obligations as citizens, but because everyone does various activities, their rights and obligations are often forgotten. In state life, sometimes the rights of citizens face each other's obligations. So the writing of this article aims to find out the mapping of citizenship rights and obligations broadly which can be the basis of an intrinsic study by citizens in shaping civil society. Writing this article uses the library study method. The results of this study are theoretical explanations about (1) Overview of citizenship. (2)The mapping between complex rights and obligations of citizens. (3) Citizenship Education as an instrument to strengthen the intrinsic value of citizens' rights and obligations. (4) Establishment of civil society. And (5) Discussion.
Abstrak
Hak dan kewajiban merupakan salah satu elemen penting yang perlu di rawat oleh negara. Dalam konteks kewarganegaraan, hak dan kewajiban menjadi nilai dasar secara intrinsik warga negara dalam membangun sebuah masyarakat sipil. Hampir semua orang telah memahami antara hak dan kewajiban sebagai warga negara, akan tetapi karena setiap orang melakukan aktivitas yang beragam maka apa yang menjadi hak dan kewajibannya seringkali terlupakan. Dalam kehidupan kenegaraan kadang hak warga negara saling berhadapan dengan kewajibannya. Maka penulisan artikel ini bertujuan untuk mengetahui pemetaan hak dan kewajiban kewarganegaraan secara luas yang dapat menjadi dasar kajian secara intrinsik oleh warga negara dalam membentuk masyarakat sipil. Penulisan artikel ini menggunakan metode studi kepustakaan. Hasil penelitian ini berupa penjelasan secara teoretis tentang (1) Sekilas tentang kewarganegaraan. (2) Pemetaan antara hak dan kewajiban warga negara secara kompleks. (3) Pendidikan Kewarganegaraan sebagai instrumen penguatan nilai intrinsik hak dan kewajiban warga negara. (4) Terbentuknya masyarakat sipil. Dan (5) Diskusi.
KONSEP POLIGAMI DALAM ALQURAN: STUDI TAFSIR AL-MISBAH KARYA M. QURAISH SHIHAB
Authors: Asiyah Siti , Irsad Muhammad , Prasetiawati Eka , Ikhwanudin Ikhwanudin 
Published: August 2019

This paper aims to understand the interpretation of the polygamy verse from the perspective of contemporary Indonesian interpreters represented by M.Quraish Shihab as a problem solving for the rampant practice of polygamy in society. The discourse of polygamy in Islamic thought is an interesting controversy discussed. As offered by M. Quraish Shihab in his interpretation that polygamy in Islamic teachings is permissible not as a recommendation or as a mandatory thing, even then on fair terms. The existence of differences in each argument has the same basis of the Qur'anic text, namely Surat an-Nisa 'verse 3. The practice of polygamy sometimes has an impact on family relations that are not harmonious and unfair, on this basis polygamy needs to be reviewed with other approaches. To limit the study in this paper, this research uses a qualitative approach by applying a thematic interpretation method to obtain a comprehensive understanding of polygamy in the Qur'an. Polygamy in al-Misbah's interpretation is said to be fair, just here is not only immaterial (love and affection) but justice in measured material is not only obeying lust.
Abstrak
Tulisan ini bertujuan memahami tafsir ayat poligami perspektif mufassir Indonesia kontemporer yang diwakili oleh M.Quraish Shihab sebagai problem solving atas maraknya praktek poligami di masyarakat. Wacana poligami dalam pemikiran Islam menjadi kontroversi yang menarik dibahas. Sebagaimana ditawarkan M. Quraish Shihab dalam tafsirnya bahwasanya poligami dalam ajaran Islam diperbolehkan bukan bersifat anjuran atau hal yang wajib, itupun dengan syarat adil. Adanya perbedaan setiap argumen mempunyai dasar yang sama dari teks al-Qur’an yaitu surat an-Nisa’ ayat 3. Praktik poligami terkadang berdampak pada hubungan keluarga yang tidak harmonis dan kurang adil, atas dasar ini poligami perlu dikaji ulang dengan pendekatan-pendekatan lain. Untuk membatasi kajian dalam tulisan ini maka, Penelitan ini menggunaan pendekatan kualitatif dengan menerapkan metode tafsir tematik (maud}u>’i) untuk memperoleh pemahaman yang komprehensif tentang poligami dalam al-Qur’an. Poligami dalam tafsir al-Misbah dikatakan boleh dengan syarat adil, adil di sini bukan hanya bersifat immaterial (cinta dan kasih sayang) melainkan keadilan pada materi yang terukur bukan hanya menuruti hawa nafsu.
SOSIO-RELIGIUS PESANTREN: AKTUALISASI NILAI-NILAI AGAMA DALAM RUANG SOSIAL KEMASYARAKATAN DI LOMBOK TIMUR
Authors: War'i Muhammad 
Published: August 2019

This paper discusses the socio-religious attitude of the pesantren which is manifested by the Islamic Boarding School Ma'had Darul Quran wal Hadith Al-Majidiyah As-Syafi'iyah Nahdlatul Wathan in a social context. Through the phenomenology approach, this research will elaborate on this. Islamic boarding schools are often represented by santri learning places with strict pesantren regulations. The santri stayed in certain locations (dormitories) with 24-hour caregiver supervision. This fact often leaves “empty spaces” in the form of "gaps" that occur between pesantren and society in general. Therefore a pesantren management model is needed which emphasizes the process of social interaction in its existence. The conclusion of this paper is the socio-religious attitude of the pesantren which is manifested in the form of intense social interaction between santri and society. This is because santri lodgings are scattered throughout the community houses in Pancor Village which is the location of the Islamic boarding schools. These socio-religious attitudes can be seen from the concern of santri to the community in helping people around to study the religious sciences and help them in matters of daily living.
Abstrak
Tulisan ini membicarakan sikap sosio-religius pesantren yang termanifestasikan dalam orientasi Pesantren Ma’had Darul Quran wal Hadits Al-Majidiyah As-Syafi’iyah Nahdlatul Wathan dalam konteks sosial kemasyarakatan. Melalui pendekatan fenomenologi, penelitian ini mengelaborasi hal tersebut. Pesantren sering kali direpresentasikan dengan tempat belajar santri yang cenderung ketat secara pemondokan. Diinapkan di lokasi tertentu (asrama) dengan pengawasan pengasuh selama 24 jam. Kenyataan tersebut sering kali meninggalkan ruang kosong berupa “gap” yang terjadi antara pesantren dan masyarakat secara umum. Oleh karena itu dibutuhkan model pengelolaan pesantren yang memuat bahkan menekankan proses interaksi sosial dalam eksistensinya. Kesimpulan yang diperoleh dari penelitian ini adalah sikap sosio-religius pesantren yang termanifestasi dari bentuk interaksi sosial yang intens antara santri dan masyarakat. Hal ini disebabkan karena pemondokan santri disebar di seluruh rumah masyarakat di Kelurahan Pancor yang merupakan lokasi pondok pesantren. Sikap sosio-religius tersebut tampak dari kepedulian santri kepada masyarakat dalam membantu masyarakat sekitar mempelajari ilmu-ilmu agama serta membantu mereka dalam urusan hidup sehari-hari.