bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reaching to Visual Targets in the Virtual and Real-Worlds
Authors: Spitzley Kate A. , Hoffman Zachary A. , Perlman Samuel E. , Karduna Andrew R. 
Published: November 2024

Abstract

Virtual reality has rapidly gained popularity and accessibility in recent years, leading to its introduction in a range of settings including clinical assessment and training. However, evidence of altered neural processing and movement patterns in virtual reality call to question its suitability for certain purposes and highlight the importance of context-specific testing prior to deployment. Upper limb movements are nearly ubiquitous within virtual applications and are frequently prescribed in injury and neurorehabilitation settings, making them important targets for investigation. Therefore, this study examined differences in kinematics and kinetics of visually cued, upper limb reaching movements between real-world and virtual reality environments. Kinematics and kinetics were quantified using HTC VIVE trackers on the trunk and reaching limb and EMG sensors on the reaching limb. In virtual reality, movements were slower, took longer to initiate, were less smooth, and employed a more elbow-focused movement strategy than in real-world. These results stand with previous findings indicating differences in movement patterns between real and virtual settings.
Factors Influencing Decision-making for Institutional Delivery in Rural Nepal: A Qualitative Study
Authors: Acharya Shijan , Gautam Anju , Bharati Tulasa , Busza Joanna , Christofori-Khadka Monika 
Published: November 2024

Abstract

Maternal mortality is a critical global issue, with approximately 800 preventable deaths occurring daily in 2020, predominantly in low and lower middle-income countries. Nepal, recording 151 maternal deaths per 100,000 live births in 2021, faces significant challenges despite efforts to increase institutional deliveries. This study examines the decision-making processes surrounding childbirth, in the rural districts of Nepal, focusing on the roles of family and community members and factors influencing the decision-making choice for utilization of institutional delivery. Using purposive sampling technique, the study conducted thirty-four semi-structured interviews with women who had recently given birth, along with their husband and mothers-in-law. Additionally, nine key informant interviews with health workers and local authorities, and eight focus group discussions were held with women, men, health workers and local stakeholders. Thematic (Bottom-up) approach was employed to identify relevant themes and sub-themes initiated by codes and categories. The study found that decision-making about seeking care is dynamic and influenced by various factors throughout pregnancy and labour. While women are increasingly involved in decision-making during the pregnancy, the responsibility often shifts to family members, particularly husbands and mothers-in-law, once labour begins. Key factors influencing care-seeking decisions included fear of complications, previous obstetric experiences, perceived competence of healthcare providers, and role of community people. Despite birth preparedness plans, many women still failed to reach health facilities on time. The findings highlight the need to include husbands and family members in birth preparedness counselling and awareness programs to ensure timely care-seeking decisions. Emphasizing the urgency of timely care, building trust between healthcare providers and families, and improving service quality are crucial for promoting institutional deliveries.
Space oddity: Absence of prezygotic-premating barriers in Eurydema lundbladi and Eurydema ornata
Authors: Alamo Mario , Gil-Tapetado Diego 
Published: November 2024

Abstract

Understanding the effectiveness of premating prezygotic reproductive barriers in contact zones of closely related lineages is essential for assessing hybridization risks. This study documents the first overlap zone with interspecific copulations on La Palma Island, Canary Islands, between the Macaronesian endemic Eurydema lundbladi Lindberg, 1960 and the widespread Palearctic species Eurydema ornata (Linnaeus, 1758). We analyzed morphological differences in male genitalia, climatic niches, and altitudinal distributions of both species. Notably, the differences in male genital structures do not appear sufficient to cause copulatory incompatibility, nor do size variations act as limiting factors for mating. The ecological niches of both species, while distinct, converge in certain altitudinal zones, where climatic conditions–particularly winter temperatures–significantly influence their distribution. These weak and convergent premating prezygotic reproductive barriers underscore the conservation risks faced by E. lundbladi in light of the potential expansion and competition from E. ornata. Implications for insect conservation: The genetic integrity of E. lundbladi is threatened by the encroachment of E. ornata into previously unoccupied areas. Continued monitoring of contact zones and future studies are essential to evaluate the impact of these interactions on the conservation of this endemic species.
Study on Improvement of Service Load Balance in Soft Switching Server Group
Authors: Rim Ju Song , Ri Man Gun 
Published: November 2024

Abstract

The current telephone communication service mainly uses the call control signaling protocol like SIP and the multimedia dialogue based on SIP ensures high real-time characteristic. However, compared to traditional Web groups, database groups and file system groups, it must be improved in some aspects including system throughput, system response time and fault tolerance. This paper focuses on the load balancing technique which can be used in the SIP server group. First, some load balancing techniques being currently used in some SIP situations are analyzed and compared. Based on it, the paper proposes the novel load balancing method and compares its performance with the previous ones via the experiment which shows that the proposed method outperforms the previous ones with reference to the estimation of load over the service nodes.
Enhanced Novelty approaches for Resource Allocation Model for Multi-Cloud Environment in Vehicular Ad-Hoc Networks
Authors: S Nici Marx V , P SUNDARAVADIVEL , R Augustian Isaac , D Elangovan 
Published: November 2024

Abstract

As the number of service requests for applications continues increasing due to various conditions, the limitations on the number of resources provide a barrier in providing the applications with the appropriate Quality of Service (QoS) assurances. As a result, an efficient scheduling mechanism is required to determine the order of handling application requests, as well as the appropriate use of a broadcast media and data transfer. In this paper an innovative approach, incorporating the Crossover and Mutation (CM)-centered Marine Predator Algorithm (MPA) is introduced for an effective resource allocation. This strategic resource allocation optimally schedules resources within the Vehicular Edge computing (VEC) network, ensuring the most efficient utilization. The proposed method begins by the meticulous feature extraction from the Vehicular network model, with attributes such as mobility patterns, transmission medium, bandwidth, storage capacity, and packet delivery ratio. For further analysis the Elephant Herding Lion Optimizer (EHLO) algorithm is employed to pinpoint the most critical attributes. Subsequently the Modified Fuzzy C-Means (MFCM) algorithm is used for efficient vehicle clustering centred on selected attributes. These clustered vehicle characteristics are then transferred and stored within the cloud server infrastructure. The performance of the proposed methodology is evaluated using MATLAB software using simulation method. This study offers a comprehensive solution to the resource allocation challenge in Vehicular Cloud Networks, addresses the burgeoning demands of modern applications while ensuring QoS assurances and signifies a significant advancement in the field of VEC.
Quantum-inspired gravitational search algorithm-based low-price binary task offloading for multi-users in unmanned aerial vehicle-assisted edge computing systems
Authors: Ghosh Santanu , Kuila Pratyay , Bey Marlom , Azharuddin Md 
Published: November 2024

Abstract

Unmanned aerial vehicles (UAVs)-assisted edge computing (EC) brings computing resources closer to smart mobile devices (SMDs). Users of SMDs with limited resources can experience the flavor of computation and data-intensive applications. Users conserve energy by offloading resource-intensive tasks to edge servers (ESs) or UAVs. While offloading may introduce communication delays, leveraging ample wireless bandwidth can mitigate this issue by facilitating faster data transmission rates. However, mobile service providers (MSPs), facilitating offloading infrastructure, impose charges on users for bandwidth usage. Efficient utilization of limited computation units (CUs) is crucial. This paper introduces a binary task offloading (BTO) model for multi-user in multi-UAV-assisted EC systems using a quantum-inspired gravitational search algorithm (QGSA). Quantum encoding and decoding of the agents are provided. The decoding phase uses a novel hashing. The fitness function considers energy, delay, price, and resource utilization. Two penalties are incorporated with the fitness to discard the decoded agent that violates the constraints of the BTO model. The proposed QGSA ensures polynomial time execution. The proposed work is extensively simulated in multiple scenarios and compared with existing approaches. It is observed that the QGSA outperformed other algorithms in terms of delay, energy, resource utilization, and price. Analyses of convergence and statistics are performed.
Enhancing Preservation of Ancient Buildings through Color Imagery Analysis and Activation: Take Yuelu Academy as an Example
Authors: Huang Qian , Liu Keyi , Gu Jianan , Yang Zhaozhe , He Yi , Zhao Yishen 
Published: November 2024

Abstract

The pivotal role of color imagery analysis and activation has been insufficiently explored in the realm of historic heritage conservation. This study addresses this issue by introducing a comprehensive methodological framework that encompasses acquisition, analysis, activation, and application of color information based on the NCD color system, an innovative color semantic quantification theory. Utilizing the venerable Yuelu Academy (from A.D. 976) as a case study, color imagery analysis methods across diverse spatial scales have been summarised. Subsequently, these results are applied to activate the surrounding environment color, as well as its cultural souvenirs. The methodologies outlined herein hold profound significance in addressing challenges concerning visual color continuity in the preservation of historic architectural landscapes, offering innovative perspectives.
Anais 6º Encontro de Revisão Sistemática e/ou Meta-Análise, Programa de Pós-Graduação em Odontologia da Faculdade de Odontologia de Araçatuba – UNESP, Edição 2023
Authors: Pellizzer Eduado Piza , Pesqueira Aldiéris Alves , Limírio João Pedro Justino de Oliveira 
Published: November 2024

Caro(a) Leitor(a)
Em 23 de novembro de 2023, tivemos o prazer de realizar o 6° Encontro de Revisão Sistemática e Meta-análise do programa de Pós-Graduação em Odontologia, com a participação de 86 inscritos entre alunos de graduação, pós graduação, profissionais e professores de diferentes instituições do Brasil. Destaque deve ser dado a participação dos alunos de Pós-Graduação da Faculdade de Odontologia de Araçatuba (FOA-UNESP), apresentando os trabalhos realizados na disciplina “Fundamentos da Revisão Sistemática”. As revisões sistemáticas com meta-análise, principalmente de estudos clínicos consagraram-se com grande importância na literatura científica e ao longo dos últimos anos observou-se um grande crescimento na publicação desse tipo de revisões. Recentemente, destaca-se com o intuito de mapear o que existe sobre determinados assuntos e que não são possíveis de se realizar uma revisão sistemática, surgem as revisões de escopo. Nesse sentido convidamos o Professor Cleidiel Aparecido Araújo Lemos da Universidade Federal de Juiz de Fora – UFJF – Campus Governador Valadares para ministrar as palestras intitulada “Revisões de Escopo – Diferenças e etapas para a construção da síntese de evidência” e “Meta-análises no contexto da síntese de evidência” no período da manhã (8h às 12h) com participação ativa da plateia. No período da tarde houve a apresentação de painéis, onde estavam inscritos 54 trabalhos entre revisões sistemáticas, revisões sistemáticas com meta-análise e revisões de escopo. As revisões sistemáticas são consideradas a evidência científica mais forte, pois nos direcionam quanto a aplicabilidade clínica. Porém, destaca-se a relevância das revisões de escopo para sintetização/mapeamento de diversos assuntos que impossibilitam a execução de uma revisão sistemática, além do direcionamento para novas pesquisas. Nos encontraremos no próximo encontro de revisão sistemática em 2024, onde todos serão BEM VINDOS!
Prof. Titular Eduardo Piza Pellizzer, Coordenador do 6º Encontro de Revisão Sistemática e/ou Meta-Análise, Programa de Pós-Graduação em Odontologia da Faculdade de Odontologia de Araçatuba – UNESP, Edição 2023
Assessing Error upon Sampling Bagged Animal Feed
Authors: Combs Jennifer C , Sikora Frank , Harrison Glen 
Published: November 2024

The University of Kentucky Division of Regulatory Services explored the adequacy of the AOAC Official Method 965.16 for sampling bagged animal feed and assessed the acceptability of the sample error introduced through the sampling process. Eight feedstuffs were selected to represent a variety of feed forms, and their inherent differences in component size, with the objective of estimating the acceptability of the error introduced in the sampling process for each analyte. The findings suggest that the AOAC Official Method 965.16 is suitable for use in the collection of samples for regulatory purposes, particularly concerning mineral and drug components. The study's analysis and methodology provide valuable insights into the adequacy of the sampling method for regulatory purposes.
Reflexões sobre a Avaliação na Perspectiva da Experiência de Licenciandos em Geografia
Authors: Conceiçao Neto Breno da , Moura Jeani Delgado Paschoal 
Published: November 2024

A avaliação ainda é um assunto que gera controvérsias, conflitos e desafios na formação do professor e também na sua aplicação. É uma ação totalmente vinculado ao ensino como também a aprendizagem. E por esse fator, vê-se necessidade de refletir a respeito da avaliação por meio das experiências que futuros professores estão experienciando por meio da observação participante e das entrevistas. Deste modo, este estudo tem o objetivo de é apresentar algumas ideias e percepções a respeito da avaliação com alunos em formação inicial em Licenciatura em Geografia. Tendo como questão norteadora: Como a observação participante pode auxiliar a compreender as experiências e vivências sobre a avaliação da aprendizagem? Metodologicamente, o artigo baseia-se na pesquisa qualitativa, com coleta de dados realizadas por meio da observação participante e de entrevistas. No entanto, ainda há modelo de avaliação cristalizado enquanto uma prática penosa. E que, ainda gera desconforto nos estudante, E isso, pode direta ou indiretamente refletir na formação do professor e no exercício da profissão docente.
Contributos da IA nos Processos Pedagógicos e no Desenvolvimento Profissional e Organizacional: Percepções de Professores Portugueses
Authors: Madureira Cristiana Pizarro , Batista José António Flambó Afonso 
Published: November 2024

Este artigo tem como objetivo compreender os olhares de professores dos ensinos básico e secundário portugueses sobre as aplicações digitais utilizadas em contexto escolar e sobre o modo como a Inteligência Artificial (IA) poderá contribuir para a melhoria dos processos pedagógicos de ensino, aprendizagem e avaliação e para o consequente desenvolvimento e transformação profissional e organizacional.Deste modo, centramos o estudo numa abordagem quantitativa, com recurso a um inquérito por questionário dirigido a 74 professores dos ensinos básico e secundário de um Agrupamento de Escolas em Portugal. Como principais conclusões destaca-se que o recurso à IA contribui para estimular a motivação e o compromisso do aluno com as aprendizagens, através da otimização dos processos de autorreflexão e de autorregulação. A utilização da IA possibilita aos professores implementar práticas de diferenciação pedagógica, numa abordagem humanista, inscrevendo a IA enquanto recurso pedagógico promotor de uma melhoria dos processos pedagógicos, promovendo assim o desenvolvimento e a transformação das pessoas e dos contextos. O estudo demonstrou, ainda, a necessidade premente de a escola se reconfigurar e transformar, capacitando a comunidade educativa em literacia em IA, criando um código de conduta, garantindo a equidade, a inclusão e a democratização de práticas pedagógicas inovadoras com o digital.
Universidade e Território: Aproximações por Meio da Investigação-Ação-Participativa
Authors: Cichoski Pamela , Rubin-Oliveira Marlize 
Published: November 2024

O diálogo de saberes- fazeres, considerando a perspectiva decolonial, tem nos auxiliado em leituras de território que perpassam relações sociais, culturais e ambientais. Esse movimento acontece a partir das coexistências espaço-temporais, bem como perpassa debates epistêmicos e conceituais acerca da descolonização do conhecimento, voltado para a ressignificação das formas de aprender-pesquisar-fazer-ensinar, ciências ‘outras’ e populares. Esse movimento busca reforçar relações universidade-território, com mais proximidade e contextualizadas com o lugar. O que requer a tessitura de movimentos em redes de sentir e pensar o mundo, considerando as diferenças, lugares, sujeitos, naturezas e territórios. Desse modo, no presente texto, buscamos refletir sobre a Investigação-Ação-Participativa (IAP), como caminho de coprodução de saberes-fazeres socioambientais, na relação universidade-território, tendo como base nossa práxis territorial no Centro de Integração Madre Maria Domênica, em Francisco Beltrão, Paraná, Brasil. Para tanto, dividimos nossa reflexão em dois momentos, primeiro abordamos a metodologia IAP, buscando evidenciar os princípios fundamentais, fases, níveis e regras orientados pela obra de Orlando Fals Borda. E no segundo momento, buscamos refletir sobre algumas impressões acerca da coprodução de conhecimentos realizada no lugar e com os sujeitos. Assim, entre as principais aprendizagens estão a importância da inserção social com compromisso político, o que fortalece a relação sujeito-sujeito, contribuindo para o desenvolvimento de pesquisas com enraizamento territorial, e a importância de pesquisas participativas para a transformação social local.
Design, Synthesis, and Molecular Docking of Quinazolines Bearing Caffeoyl Moiety
for Targeting of PGK1/PKM2/STAT3 Signaling Pathway in the Human Breast
Cancer
Authors: Borik Rita M. , Hussein Mohammed A. 
Published: November 2024

Background:
PGK1 and PKM2 are glycolytic enzymes, and their expression is upregulated in cancer
cells. STAT3 is a transcription factor implicated in breast cancer progression and chemoresistance. Researchers
worldwide continue to explore how targeting genes might lead to more effective anti-breast cancer
therapies. The present study aims to synthesize quinazolines containing caffeoyl moiety for developing innovative
anticancer agents against the human breast cancer cell line (MCF-7).

Methods:
A new quinazoline 2 was synthesized by reacting caffeic acid with 5-amino-phenylpyrazole carboxylate
1 in the presence of PCl3. Compound 2 reacted with NH2NH2.H2O to produce compound 3 through
cyclo-condensation. Apoptosis and necrosis as well as inhibition activity compounds 2 and 3 against PGK1,
and PKM2 were evaluated. The effect of compounds 2 and 3 on the levels of GSH, GR, SOD, GPx, CAT,
MDA, Bax, Bcl-2, caspase-3, P53 and VEGF levels as well as PGK1, PKM2 and STAT3 gene expression
were estimated in MCF-7 tumor cells.

Results:
The viability of MCF-7 cells was reduced to 22.42% and 45.86% after incubation with compounds 2
and 3 for 48 hours, respectively. The IC50 values for compounds 2 and 3 are 62.05 μg/mL and 16.73 μg/mL.
Furthermore, compound 3 exhibited more significant apoptosis and necrosis than compound 2. IC50 values of
compound 2 against PGK1, and PKM2 at interval concentration equals 1.04, and 0.32 μM/mL, respectively,
after 210 minutes of incubation. Moreover, compound 3 were revealed strong inhibition of PGK1, and PKM2
with IC50 values equals 0.55 and 0.21 μg/mL, respectively after 210 minutes of incubation. Our results proved
that the incubation of compounds 2 and 3 with MCF-7 cells increased the levels of apoptotic proteins, elevated
MDA, Bax, caspase-3 and P53 levels, depleted GSH, GR, SOD, GPx, CAT, Bcl-2 levels and downregulated
the levels of STAT3, PGK1, and PKM2 gene expression significantly. Our in silico results proved
that compound 2 showed a stronger estimated binding affinity with a ΔG of -7.2, -7.5, and -7.9 kcal/mol., respectively
towards PGK1, PKM2 and STAT3 proteins. Also, compound 3 exhibits a strong binding affinity
with ΔG of -7.9, -8.5, and - 8.7 kcal/mol., towards PGK1, PKM2 and STAT3 proteins.

Conclusion:
The results show that compounds 2 and 3 induce apoptotic activity by blocking the PGK1-
PKM2-STAT3 signaling pathway. The present investigation opens exciting possibilities for developing innovative
new anticancer quinazolines bearing caffeoyl moiety.
Synthesis, Reaction, and Biological Activity of Thiazoles
Authors: Alateeq Aisha M. , Al-Faiyz Yasair S. , McNair Olivia D. , Wiggins Jeffery S. , Sayed Abdelwahed R. 
Published: November 2024

Abstract:
The current review aimed to provide an understanding of the preparation, reactions,
and biological action of thiazoles. The purpose of this review was to focus on the progress made
in the synthesis of physiologically effective thiazole products with their interactions. A combinatorial
approach was proposed, and extensive attempts were made in the search for thiazoles by
chemists in many domains due to the information of multiple artificial pathways and variable
physics-chemical factors of thiazoles. In this regard, the biological activities linked to thiazole
and the processes used in its production were thoroughly discussed in this study. The research
period covered in this review was from 1905 to 2024, providing a useful and convenient strategy
for the synthesis of numerous thiazole derivatives. Moreover, research on such reactions is still
ongoing and undoubtedly will provide new fused functionalized compounds of both industrial
and biological interests. A literature survey revealed that a great deal of interest has been focused
on the synthesis and reaction of thiazoles due to their wide range of biological activities.
Remarkable insights into different synthetic paths and modified physical-chemical features of
such thiazoles would be helpful for chemists worldwide.