bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUATION OF CYTOKINES AND HEAT SHOCK PROTEIN IN VIBRATION DISEASE
Authors: Bodienkova G. M. , Kurchevenko S. I. 
Published: December 2018

The prolonged impact of industrial vibration on workers leads to the development of a vibrational disease (VB), which occupies a leading position in the structure of occupational pathology. VB from the impact of local vibration is a chronic occupational disease characterized by a predominant lesion of the nervous, vascular system and musculoskeletal system of the upper and lower extremities. One of the real ways to reduce the incidence is the early detection of the negative impact of vibration on the body of workers. In this regard, cytokines and heat shock proteins (HSP70) can be early and sensitive indicators that reflect the severity of health disorders from exposure to vibration. The aim of the study was to study changes in the content of pro- and antiinflammatory cytokines, extracellular HSP70 and their relationship in patients with VB. In the immunological study included 43 male patients with a diagnosis of VB. The criteria for inclusion in this group were: a verified diagnosis, written informed consent to participate in the study, the harmful effects of local vibration in the workplace. According to the data of hygienic control, the working conditions of workers in dangerous occupations by vibration belong to the 4 (dangerous) class due to intensive local vibration. The content of cytokines: IL-1β, IL-8, IL-10, TNFα and HSP70 in the serum of patients was determined by enzyme immunoassay. The blood sampling for the study was taken from patients only once on admission to the hospital before the treatment. Statistical processing of data was carried out with the help of packages of application programs Statistica for Windows 6.0 and Microsoft Excel. It was established that the development of VB disease is accompanied by imbalance of the cytokine profile, characterized by a decrease in the levels of IL-1β, IL-10 and an increase in IL-8. The inhibition of production of IL-1β and IL-10 is a consequence of the chronic process that has developed in the body of the patients examined. And the revealed decrease in extracellular concentration of HSP70 in comparison with practically healthy people can be caused by the accumulation of it inside the cell or on its surface. Correlation analysis revealed the relationship between a decrease in HSP70 and an increase in IL-1β, and a decrease in IL-10 levels. Synthesis of HSP is an intracellular defense mechanism that prevents cell damage by activating the synthesis and secretion of pro-inflammatory cytokines. The obtained relationships between cytokines and HSP70 testify to the involvement of HSP70 in immunoinflammatory processes in VB. The revealed changes contribute to the chronic inflammatory process and justify the progressive course of the VB.
СHANGES OF IMMUNOREGULATORY INDEXES IN CHILDREN EXPOSED TO STRONTIUM
Authors: Otavina E. A. , Dolgikh O. V. , Starkova K. G. , Kazakova O. A. , Mazunina A. A. 
Published: December 2018

Evaluation of the immune system parameters can be used in order to assess capacity to adapt under conditions of increased external chemical load, including exposure to metals, which can exert either activating and inhibitory effects upon immune regulation parameters. The aim of this work was the analysis of immunoregulatory markers in a children’s population who consumed water with high strontium content (a sample from the Perm region). We carried out immunological evaluation of the children aged 7 to 12 years, living at a territory with a high strontium content in the drinking water. The comparison group included children from the conventionally clean region. We studied differential changes in cellular immunity (phagocytosis rates), humoral factors of immune defense (serum immunoglobulins), development of specific sensitization for strontium, as well as the processes of apoptosis triggering and regulation. A 3.68-fold increase in strontium levels was shown in fresh water within observation area, and the average blood strontium content in the children of appropriate observation group was 1.55-fold higher than in children of the comparison group. At the same time, 1.2-fold increase in phagocytic activity determined as phagocytic number and phagocytic index was found, as compared to the control group. In 80% of the subjects, a reduction in serum IgG level was observed when compared to physiological norm, as well as a significant decrease in IgG and enhance in IgM production against the levels found in the comparison group. Wehave also shown an enhanced total sensitization in 55.0% of the observation group as shown by the total IgE test compared with normal age ranges, as well as excessive specific sensitization to strontium by 2.49 times, according to the IgG criterion. Disturbance in apoptosis triggering was associated with decreased number of CD95+ lymphocytes and TNFR1+ cells (2.8-fold compared to reference values), shifted balance in apoptogenic proteins, an average of 2.6-fold decrease in Bcl-2 expression, a 2.8-fold reduction of the p53 transcription factor expression relative to the reference interval. Thus, we have shown an ability of strontium excess in drinking water to influence the most important indices of immune regulation in pediatric population. These changes may serve as indices of populational health status under of external strontium exposure.
INTERGENIC INTERACTIONS OF CYTOKINE GENES IL1, IL1RA, IL6, IL10 AND TNFА IN PATIENTS WITH IRRITABLE BOWEL SYNDROME AND ULCERATIVE COLITIS IN RUSSIAN POPULATION OF THE CHELYABINSK REGION
Authors: Stashkevich D. S. , Belyaeva S. V. , Filippova Yu. Yu. , Burmistrova A. L. 
Published: December 2018

Сomplex intergenic interactions should be taken into account when predicting the risk of adverse course in a pathological process. This presumption is at the heart of evolving multifactorial diseases (ulcerative colitis and irritable bowel syndrome). A single genetic polymorphism seems to be a weak risk factor when predicting the disease evolution and it could not be used as a prognostic model for development of multifactorial pathologies, especially in cases of rare alleles. However, it is well known that the combination of unfavorable alleles of several genes with an additive effect is dangerous. Therefore, identification of such polymorphisms is very important.Previously we conducted a test panel, in order to evaluate associations of alleles and genotypes of some cytokine genes (IL1β, TNFα, IL1rа, IL10, IL6) with predisposal, or resistance for ulcerative colitis and irritable bowel syndrome in the Russian Chelyabinsk region. Distribution of alleles and genotypes of these genes have been assessed in irritation bowel disease (IBD) and ulcerative colitis (UC). The following methods were used: isolation of DNA samples from whole blood, genotyping of the studied gene polymorphisms with PCR, RFLP. A comparative analysis of intergenic interactions between the cytokine genes IL1β, TNFα, IL1ra, IL10, IL6 in the IBD and UC patients was carried out by the Multifactor Dimensionality Reduction method. The analysis is based on the use of polymorphic loci of IL1β, TNFα, IL1ra, IL10, IL6 combinations chosen for analysis of intergenic interactions, with respect to the risk for IBS and UC predisposition. As a result of this study, a fourlocus model IL1β(+3953)*Т/TNFα(-308)*A/IL10(-1082)*G/IL6(-174)*G was identified for IBS, which was characterized by 90% repeatability and prediction accuracy of 74.5%. This model of gene interactions between the cytokine IL1β, TNFα, IL1ra, IL10, IL6 genes had the greatest prediction potential (p < 0.001) in IBS, whereas the model for UC was not statistically significant. The following types of genetic interactions were established: synergism between the IL1β(+3953)*Т and TNFα(-308)*A loci, whereas IL6(-174)*G и IL10(-1082)*G, TNFα(-308)*A seem to be in antagonistic relationships. The study made it possible to establish that the -174G/C IL-6 polymorphism may play a central role and provide intergenic interactions with SNPs of IL1β, TNFα, IL10 for predisposal to irritable bowel syndrome in Chelyabinsk Region of Russia.
Quantity and Reporting Quality of Kidney Research
Authors: Chatzimanouil Markos Kyriakos Tomidis , Wilkens Louise , Anders Hans-Joachim 
Published: December 2018

Background
In 2004, researchers reported that the number of nephrology clinical trials was low and that the reporting quality of such trials was suboptimal. Furthermore, the number or quality of preclinical kidney-related studies has not been systematically evaluated.

Methods
We performed a systematic review of randomized clinical trials published in 1966–2017 (listed in the Cochrane Library) and preclinical studies published in 1945–2017 (listed in PubMed). For reporting quality analysis, we evaluated the final main paper of 118 clinical trial reports and 135 preclinical studies published in leading journals in 1996, 2006, and 2016 on the basis of criteria from the widely used CONSORT and ARRIVE guidelines.

Results
The annual number of reports of clinical kidney-related trials more than doubled between 2004 and 2014 along with reports in other medical disciplines. Hypertension remains the dominant focus of study, but ongoing trials also center on CKD, ESRD, and AKI. The reporting quality analysis revealed improvements, but deficits in reporting of clinical trial design, mode of randomization, and intention-to-treat analysis remain. Annual numbers of kidney-related preclinical studies remained low between 1945 and 2017 compared with other disciplines. Reporting quality analysis of preclinical studies revealed substantial reporting deficits across all leading journals, with little improvement over the last 20 years, especially for group size calculations, defining primary versus secondary outcomes, and blinded analysis.

Conclusions
Nephrology studies keep increasing in number but still lag behind other medical disciplines, and the quality of data reporting in kidney research can be further improved.
Aproximación a un modelo sobre antropología de la Asistencia
Authors: Comelles Josep Maria , Andreu Agustí , Ferrús Jordi , París Serra 
Published: December 2018

El campo de la Antropología de la Medicina está lejos de presentar la concreción y la consistencia teórica que parecería corresponderle a tenor de su ya larga historia. Nacido a principios de siglo como una subespecialización de la Etnología de sociedades primitivas, adquiere probablemente carta de naturaleza con la publicación de Medecine, Magic and Religion por W.H.R. Rivers en 1924. Rivers formuló una primera teorización sobre dicha materia, pero su tarea debe ser entendida más que como un punto de partida, como la concreción de una serie heterogénea de intereses.
Miembros del Departamento de Antropología de Tarragona y Plan de Estudios
Authors: Arxiu Revista 
Published: December 2018

El Departamento está constituido por cuatro profesores: Drs. Dolors Comas d'Argemir, Josep Mª Comelles, Joan Prat y Joan J. Pujadas; un becario: Jordi Ferrús; y siete colaboradores: Marta Allué, Agustí Andreu, Misericordia Domingo, Carme González, Mª Serra París, Rosa Rodríguez-Solano y Fausto Sánchez Cascado.
Informacions i cròniques
Authors: Arxiu Revista 
Published: December 2018

Primeres jornades d'Antropologia de la Medicina; III Congrès d'Antropologia; Seminaris de l'Arxiu d'Etnografia de Catalunya; Grup de Sociologia de la Medicina; Departament d'Antropologia Cultural de Tarragona; Centre d'Estudis Alcoverencs; Actes de les I Jornades d'Antropologia de la Medicina.
Informacions i cròniques
Authors: Arxiu Revista 
Published: December 2018

Els estudis d'Antropologia Social es realitzen en el marc de la llicenciatura en Història General i Geografia que s'imparteix en la Facultat de Filosofia i Lletres de Tarragona (Universitat de Barcelona). Aquest pla d'estudis és molt flexible, ja que mitjançant les assignatures optatives (dotze en total) l'alumne pot cursar les matèries corresponents a l'àrea d'Antropologia Social.a. Pla d'estudis. Cursos de llicenciaturab. Pla d'estudis. Doctoratc. Línies de recerca
La Chrysalide etouffée Crises économiques, dépopulation rurale et transformation des groupes domestiques dans un village de Vaucluse (1836-1946)
Authors: Deverre Christian 
Published: December 2018

Les études rurales ont connu en France à la fin des années 1970 un tournant assez paradoxal. La disparition de la société paysanne telle qu'elle s'était imposée aux siècles précédents semblait ouvrir la voie aux synthèses, à la présentation «définitive» du chemin in par lequel «ce monde que nous avons perdu» (pour reprendre le titre du livre de Peter Laslett) s'est transformé en un simple secteur de la société industrielle. Ne citons, après le travail pionnier de H. Mendras (La fin des paysans), que l’Histoire de la France Rurale, l'Histoire des paysans français ou la traduction française de l'ouvrage d'E. Weber, La fin des terroirs.Globalement, et avec des nuances selon les auteurs, cette transformation apparaît comme l’effet déstructurant de la société nationale industrielle qui réduit un à un les singularismes territoriaux du monde paysan, gommant ses valeurs et pratiques spécifiques pour les remplacer par celles qui régissent les cités: universalisme, innovation, circulation des hommes et des biens...
Envases alimentarios o Alimentos envasados
Authors: Castro Arachu 
Published: December 2018

Los envases se han convertido en las últimas décadas en un elemento imprescindible de la compra alimentaria. Hoy en día es imposible, salvo en contadas ocasiones, adquirir alimentos per se. Se ha llegado a un punto en que también se tienen que comprar los envases. Esta situación no sólo repercute en la economía doméstica, sino que significa un cambio profundo en el comportamiento alimentario de la población. La evolución de las técnicas de envasado, junto con las de conservación de alimentos, transforman los procesos de fabricación, distribución, compra y preparación de los alimentos, tanto a nivel empresarial como familiar.
Ve no sé dónde, trae no sé qué. Reflexiones sobre el trabajo de campo en Antropología de la Salud
Authors: Comelles Josep Maria 
Published: December 2018

Gog preguntó a Freud por qué se hizo psicoanalista; le contestó, resignado, que no supo escribir novelas. Soñé con ser novelista y quizás por ello quise ser psiquiatra. En mis ilusiones de adolescente no podía aceptar el fracaso que hubiese supuesto seguir una formación de letras "que no servía para mucho"; pero podía hacerlo entrando por la puerta falsa de una psiquiatría que me desencantaría pronto. Metido en esta trama, me deslicé hacia la oferta atractiva de un nuevo plan de estudios de letras y allí pude oír hablar, creo que por primera vez en mi vida, de antropología. Hastiado de una facultad de medicina en la que me preguntaba qué diantre estaba haciendo allí, me fascinó la palabra Malinowski. ¿Qué hacía un polaca Kaiserlicht und Königlicht en las islas por las que navegó Nemo? Perseguí su nombre en atlas escolares por las islas del Almirantazgo pera no tuve la oportunidad de convertirme en antropólogo como él, recorriendo los mares del Sur de las aventis de mi niñez, nutridas de programas dobles en el Nuria, el Versalles, el Chile, el Máximo, el Texas, el Triana, el Venus o el Nápoles.
SIDA, ciencia y sociedad en México, per Jaime Sepúlveda y otros
Authors: Martínez Montserrat 
Published: December 2018

Una obra exhaustiva y obligada para los científicos sociales por el planteamiento interdisciplinar que supone abordar el tema del SIDA desde las perspectivas biológica y médica (capítulos II al XI) y social (capítulos XII al XXI). Destaca el capítulo dedicado al estudio de las distintas subpoblaciones en cuanto a actitudes frente a la enfermedad y prácticas sexuales sobre la misma (Izazola et al., cap. XIV), sobre todo porque sirve de base para el diseño de programas educativos. Dichos programas comprenden el enfoque más sereno y maduro de todo lo leído hasta el momento, adecuando la formación e información con el canal más sensible para cada grupo, lo que denota una visión real y acertada, en función de la permanente búsqueda de efectividad presente en toda la obra.
Editorial
Authors: Arxiu Revista 
Published: December 2018

En el primer semestre de 1990 apareixia el, fins avui, darrer número d'Arxiu d'Etnografia de Catalunya. Fins aleshores, la revista havia pogut mantenir amb certa regularitat el seu contacte amb els lectors, acostumats ja a la irregularitat amb que les revistes d'antropologia del nostre país posen de manifest la seva condició de productes amateurs, amb una migrada base financera. Després, una sèrie d'esdeveniments de tot ordre han endarrerit la seva continuïtat.
Hare Krisna
Authors: Vallverdú Jaume 
Published: December 2018

Per localitzar l'origen del sistema filosòfic-religiós Hare Krisna hem de remuntar-nos al saber oriental dels Vedes. Els fonaments de l'hinduisme i de la civilització hindú els trobem en la religió dels Vedes, que representa l'aspecte més antic en què es manifesten les formes religioses de l’Índia i el mateix pensament humà (Mahadevan, 1991: 17). Tot i que l'aspecte cronològic és poc precís, per algun autor el vedisme és introduït a la Índia nord-oest (el Punjab, conca de l'alt Indo) pels invasors aris entre el 2000 i 1500 abans de la nostra era (Renou, 1991: 9). Es confondria amb el brahamanisme, com a religió de les èpoques antigues, mentre que hinduisme es referiria més a l'evolució religiosa a partir del període vèdic, que els textos històrics acostumen a situar entre el 1400 i el 400 aC.
L'ex-sectari com a producte social
Authors: Sentís Roser 
Published: December 2018

El discurso que sobre las instituciones definidas socialmente como sectarias elaboran algunos de sus ex miembros, es el tema de este artículo. En él se analizan cuáles son las circunstancias y factores (tanto personales como sociales) que rodean el surgimiento del discurso, condicionándolo en gran parte en su naturaleza y en su contenido. La idea principal es que el discurso antisectario de estas personas se explica, más que por su experiencia como antiguo miembro, por su etiquetaje social actual como exsectario y las "obligaciones" que esta nueva identidad conlleva.El discurs que sobre les institucions definides socialment com a sectàries elaboren alguns dels seus ex-membres és el tema d'aquest article. Hom hi analitza quines circumstàncies i factors (tant personals com socials) envolten el sorgiment del discurs, condicionant-lo en gran part en la seva naturalesa i contingut. La idea principal és que el discurs antisectari d'aquestes persones s'explica, més que per la seva experiència com a antics membres, pel seu etiquetament social actual com a ex-sectaris i les "obligacions" que aquesta identitat comporta. Le discours que sur les institutions définies socialement comme sectaires élaborent certains de ces ex-membres est le thème de cet article. Dans celui-ci s'analyse quelles sont les circonstances et les facteurs (tant personnels comme sociaux) qui entourent le jaillissement du discours, en le conditionnant en grande partie dans sa forme et contenu. L'idée principale est que le discours anti-sectaire de ces personnes s'explique, plus que par leur expérience comme ancien membre, par leur étiquetement social actuel comme ex-sectaire et les «devoirs» que cette nouvelle identité implique.The theme of this article is the argument put forward by some of the ex-members of the institutions socially defined as sectarian. The article analyses which personal and social circumstances and factors surround the emergence of this argument, also greatly conditioning its nature and content. The main idea is that the anti-sectarian argument given by these people may be explained more by society's current labelling of them as ex-sectarians and the "obligations" implied by this new identity, rather than by their experience as former members.
Entrevista a Bryan Wilson
Authors: García Jorba Juan M. 
Published: December 2018

Bryan R. Wilson és una de les figures cabdals de la Sociologia de la Religió i tota una institució a Anglaterra. Imparteix classes de Sociologia a All Souls, Oxford, i cal destacar les seves aportacions a l'estudi del sectarisme i de la secularització. Religion in Secular Society (1966), Religious Sects (1970), Magic and the Millennium (1975), Contemporary Transformation of Religion (1976), Sects and Society (1978) i Religion in Sociological Perspective (1982), juntament amb la compilació The Social lmpact of New Religious Movements (1981), són un bon exemple de la seva excepcional producció. A continuació es detalla el contingut de l'entrevista d'hora i mitja de duració que es va mantenir a les seves habitacions privades a All Souls el dia 10 de Juny de 1993.
A KAP study of oral health status among adults in a rural area of Jammu District
Authors: Bala Kiran , Gupta Reecha , Ara Anjum , Sahni Bhavna 
Published: December 2018

Background: Oral health is an integral part of general health and well being. It is important to know about the factors which having a bearing on oral health so that preventive measures can be taken. A research activity was planned to assess the oral health status and oral health practices of people in a rural community of Jammu region as very little is known about the knowledge and oral health practices of adults residing in this area.Methods: A cross sectional study for a period of four months was conducted in a village Tanda of R.S.Pura block of Jammu district. 324 adults above the age of 20 years (145 males and 179 females) were interviewed face to face with the help of a questionnaire consisting of questions from WHO technique of self assessment of oral health along with some more questions exploring the knowledge, attitude and local oral health practices.Results: The overall results showed adequate knowledge but poor attitude regarding oral health. Out of 324 subjects studied, 41.7% paid dental visits on having pain in teeth, gums or mouth and only 3.0% visited dentist routinely. 85.6 % of participants reported using brush and toothpaste but only 24.0% of all respondents brushed twice a day and only 16.7% of the respondents changed their tooth brush within three months.Conclusions: Oral health awareness, by promoting community based programs should be undertaken at periodic intervals for better oral health and hygiene.