bluuebunny/crossref_metadata_2025_split huggingface dataset:
The economic and humanistic burden of patients in receipt of current available therapies for nAMD
Authors: Jaffe Dena H , Chan Wing , Bezlyak Vladimir , Skelly Adrian 
Published: September 2018

Aim:
To determine the economic and humanistic burden of neovascular age-related macular degeneration (nAMD) in a cohort of patients treated with anti-VEGF in Europe and the US.
Patients & methods:
79 respondents from the EU and 63 from the US with a self-reported diagnosis of nAMD and in current receipt of treatment, as reported in an international, general population survey, were compared with non-nAMD controls.
Results:
Anti-VEGF-treated nAMD patients in the EU had a greater utilization of healthcare resources, poorer quality of life and greater overall activity impairment versus non-nAMD controls. In the US cohort, treated nAMD patients had significantly greater resource utilization for ophthalmologist visits only.
Conclusion:
The burden of care associated with nAMD on EU and US healthcare systems, and on patients who are in receipt of nAMD therapy, is significant and likely to be unsustainable.
PERSEPSI MASYARAKAT PADA PENDIDIKAN ISLAM DI IAIN PALANGKA RAYA (KAJIAN MOTIVASI MASYARAKAT UNTUK MASUK KE IAIN PALANGKA RAYA)
Authors: Hartati Zainap 
Published: September 2018

<p>IAIN Palangka Raya merupakan satu-satunya perguruan Tinggi Islam Negeri yang ada di Kalimantan Tengah, walaupun terdapat beberapa perguruan tinggi baik negeri maupun swasta dari berbagai lintas agama yang ada di Kalimantan Tengah. Kota Palangka Raya memiliki Visi sebagai kota pendidikan dan terdapat satu Madrasah Alyah Negeri dan 6 Madrasah Aliyah Swasta, keberadaan 7 (tujuh) madrasah ini merupakan potensi dan prospek yang menguntungkan untuk input mahasiswa ke IAIN Palangka Raya, namun demikian berdasarkan data tentang mahasiswa yang kuliah di IAIN Palangka Raya, belum mendominasi latar pendidikan adalah lulusan siswa Madrasah Aliyah. Realitas ini juga menjadi kajian yang menarik, data dilapangan mengungkapkan berbagai faktor yang mengungkapkan persepsi dan motivasi masyarakat yaitu orangtua untuk menjadikan IAIN palangka Raya sebagai lembaga pendidikan tinggi bagi anak-anak mereka. Keinginan untuk memberikan pendidikan anak ke IAIN Palangka Raya didukung dengan ketersediaan daya/biaya, beasiswa dan anak kuliah samabil bekerja. Kondisi ini juga menjadi daya tarik IAIN untuk dapat menjaring bagaimana dapat menyahuti keinginan orangtua sehingga IAIN menjadi idole atau pilihan utama bagi orangtua untuk pendidikan anak-anaknya.</p>
Riba and Justification in Practice in Scholars' Views
Authors: Meirison Meirison 
Published: September 2018

<p class="Abstract"><strong>Abstract:</strong> Efforts have long been focused on trying to explain and justify riba (Usury) and dozens of theories have emerged in this area. This approach went to some Islamic economics writers, who also tried to justify and interpret interest in accordance with the principles of Islamic economics. This is one of the most important economic topics in the past and present, and although the writings on some of the elements of this subject began about half a century ago, but the observer renewed the introduction of these views and ideas in different formats in the present era, Islamic economics issues only show a picture of this subject for discussion. Therefore, this discussion aims to collect these opinions and theories and evaluate them in order to present them to the new discussioners - with different scientific backgrounds - in a suitable manner that serves to discuss this subject and clarify the general framework for it. This discussion will focus briefly on the presentation of some of these theories, opinions and justifications and discuss the hypotheses of these views and theories.</p><p><em> </em></p><p><strong><em>Keywords</em></strong><em>: Riba, Justification</em><strong></strong></p>
PENERAPAN PENDEKATAN KONSTRUKTIVISME SEBAGAI UPAYA MENINGKATKAN KEMAMPUAN MEMBACA PEMAHAMAN INTERPRETATIF BAGI SISWA
Authors: Liadi Fimeir , Darim Abu , Warjuningsing Tri 
Published: September 2018

<p>Reading is an important language skill for students. Through reading, students are able to get lots of information from various reading sources. However, after observation and interview are conducted, it shows that the ability of interpretative reading comprehension for the students still needs to be improved. Therefore, the researcher thinks that the improvement of the students’ ability in interpretative reading comprehension can be done by using constructivism approach.In relation with the effort to improve the ability in interpretative reading comprehension, the specific problem limitation studied is as follow. How far is the implementation of constructivism approach in pre reading stage, while reading stage, and post reading stage can improve the ability of interpretative reading comprehension for the students of the grade? In accordance with it, the specific objective of this research is to describe the implementation of constructivism approach in pre reading stage, while reading stage, and post reading stage.</p><p><strong><em>Keywords</em></strong><em>: </em><em>Constructivism approach, interpretative reading comprehension</em><strong></strong></p>
Pengaruh Kesiapan Perubahan Organisasional terhadap Pembelajaran Organisasional
Authors: MUAFI MUAFI 
Published: September 2018

This study examines if organizational change readiness will affect the organizational learning and using data from the Indonesian state-owned company that has recently been merged with other stated owned companies. This study devises a multifaceted model based on three constructs of organizational change readiness, namely aggressive attitude toward change, passive attitude toward change and the readiness attitude in coordination with change, and tests their effects on organizational learning, including knowledge creation and expantion. Empirical results indicate that organizational change readiness have positive affect to organizational learning. Pengaruh Kesiapan Perubahan Organisasional terhadap Pembelajaran Organisasional
Centrality Metrics for Water Distribution Networks
Authors: Simone Antonietta , Ridolfi Luca , Laucelli Daniele , Berardi Luigi , Giustolisi Orazio 
Published: September 2018

Complex Network Theory (CNT) studies theoretical and physical systems as networks, considering their features deriving from the internal connectivity between elements defined as vertex and links. In order to quantify the importance of these elements in real networked systems, researches proposed several centrality metrics.The use of CNT centrality metrics for analysis, planning and management of infrastructure networks (streets, water systems, etc.), for example in terms of reliability and vulnerability, is today a relevant issue also considering their influences in socio- economics and environmental matters. From CNT standpoint, water distribution networks (WDNs) are infrastructure networks that can be analyzed considering some peculiar features deriving from their spatial characteristics.The paper focuses on CNT centrality metrics and proposes novel hydraulic centrality metrics useful for understanding the WDNs behavior. Furthermore, the study is intended to evaluate the feasibility of coupling hydraulic and topologic centrality metrics based on links, in order to obtain information that are more useful from the hydraulic point of view. This way, centrality metrics of the CNT become a complementary tool to hydraulic modelling for WDNs analysis and management.
A Contribution to an Advisory Plan for Integrated Irrigation Water Management at Nebhana Dam System: from Research to Operational Support
Authors: Allani Mohamed , Mezzi Ranya , Abdallah Wajdi , Gharbi Amina , Zouabi Adel , Hedhli Kamel , Beji Ridha , Jemli Abdejjabar , Mansouri Joumade Farida , Afli Abdeljelil , Hamza Mahmoud Elies , Müller Hans Werner , Sahli Ali 
Published: September 2018

In the agriculture sector, combining physically based soil water balance and simulation models with GIS tools is of a considerable interest to manage the available water amount. Indeed, this combination can enhance water supply management, optimize agricultural catchments management and study impact of management intervention from small scale (plot) to a larger one, such as irrigated district and/or region.This work presents the case of Nebhana Dam System in the region of Kairoun (central Tunisia). The main objectives were to: (1) create a specific GIS database for the six irrigated districts of the area Ain Boumorra 1, 2 &amp; 3, Fadhloun, Dar Jameya and Sisseb 1 based on the characteristics of cultivated crops, soils types and used irrigation systems; (2) assess spatial and temporal variation of soil water budget terms from plot and farm levels to irrigated district and regional scales; (3) map results for different time steps.The achievement of these objectives was made possible using the WEAP-MABIA Model. Thus, daily Penman–Monteith reference evapotranspiration (ETo), effective precipitation (PE), crop water requirement (CWR) and irrigation water requirement (IWR) were estimated for the six irrigated districts and their related farms and plot using spatially distributed parameters on climate, crop, soil characteristics, irrigation system and basic irrigation management practice during the cropping season 2014/2015.
University Mission in Western-European Culture (Ethical and Sociological Aspects). P.1
Authors: Rogozha Mariya Mikhaylivna , Kurbatov Sergiy Volodymirovych 
Published: September 2018

The paper is devoted to the problem of historical development of university community through the lenses of understanding of university mission. The authors undertake critical reflections of the scheme of evolution of university mission, which was elaborated by American researcher John Scott, as far as add some theoretical and methodological suggestions to this scheme. In this respect, typical for late medieval university mission of teaching and corporate based building of university community in the modern times are supplemented by the mission of research. At the same time, university is incorporated in the system of arising nation-state as a tool for preparation highly-qualified bureaucrats for its apparatus. In postmodern times in the context of globalization and certain emancipation of the university from the state such aspects of university mission as the different forms of civil service or the third mission of university become more and more important.
ELABORAÇÃO E AVALIAÇÃO SENSORIAL DE SORVETE DIET E SEM LACTOSE DE MANGABA ENDÊMICA DO CERRADO
Authors: Almeida Ana Beatriz da Silva , Ferreira Monica Aparecida Campos , Barbosa Thaís Alves , Siqueira Ana Paula Silva , De Souza Eli Regina Barboza 
Published: September 2018

A mangaba é um fruto do cerrado, rica em ferro e fonte de vitamina C mas com alta perecibilidade. Com o objetivo de reduzir os desperdícios e aumentar o processamento desse fruto, foi elaborado um sorvete a partir da polpa do fruto, em uma formulação integral e em outra sem lactose e diet, para atender a consumidores com restrições alimentares. Os sorvetes foram analisados quanto ao pH, sólidos solúveis, acidez titulável e derretimento. E submetidos a análise sensorial por 30 provadores, que mostraram aceitação de ambos, mesmo sendo possível detectar diferença entre eles. A produção de sorvetes é viável para aumentar o processamento de mangaba e evitar desperdícios
Statistical Tracing of Magnetic Fields: Comparing and Improving the Techniques
Authors: Yuen Ka Ho , Chen Junda , Hu Yue , Ho Ka Wai , Lazarian A. , Lazarian Victor , Yang Bo , Burkhart Blakesley , Correia Caio , Cho Jungyeon , Canto Bruno , Medeiros J. R. De 
Published: September 2018

Abstract
Magnetohydrodynamic turbulence displays velocity anisotropies that reflect the direction of the magnetic field. This anisotropy has led to the development of a number of statistical techniques for studying magnetic fields in the interstellar medium. In this paper, we review and compare three techniques that use radio position–position–velocity data to determine magnetic field strength and morphology: the correlation function anisotropy (CFA), principal component analysis of anisotropies (PCAA), and the more recent velocity gradient technique (VGT). We compare these three techniques and suggest improvements to the CFA and PCAA techniques to increase their accuracy and versatility. In particular, we suggest and successfully implement a much faster way to calculate nonperiodic correlation functions for the CFA. We discuss possible improvements to the current implementation of the PCAA. We show the advantages of the VGT in terms of magnetic field tracing and stress the complementary nature with the other two techniques.
Gas Perturbations in the Cool Cores of Galaxy Clusters: Effective Equation of State, Velocity Power Spectra, and Turbulent Heating
Authors: Zhuravleva Irina , Allen Steven W. , Mantz Adam , Werner Norbert 
Published: September 2018

Abstract
We present the statistical analysis of X-ray surface brightness and gas density fluctuations in the cool cores of 10 nearby, X-ray-bright galaxy clusters that have deep Chandra observations and show observational indications of radio-mechanical active galactic nucleus (AGN) feedback. Within the central parts of the cool cores, the total variance of fluctuations is dominated by isobaric and/or isothermal fluctuations on spatial scales ∼10–60 kpc, which are likely associated with slow gas motions and bubbles of relativistic plasma. Adiabatic fluctuations, associated with weak shocks and/or sonic turbulence, constitute less than 10% of the total variance in all clusters. The typical amplitude of density fluctuations is small, ∼10% or less on scales of ∼10–15 kpc. The observed subdominant contribution of adiabatic fluctuations and the small amplitude of density fluctuations support a model of gentle AGN feedback. The measured one-component velocities of gas motions are typically below 100–150 km s−1 on scales <50 kpc and can be up to ∼300 km s−1 on ∼100 kpc scales. The nonthermal energy is <12% of the thermal energy. Regardless of the source that drives these motions, the dissipation of the energy in such motions provides heat that is sufficient to balance radiative cooling on average, albeit with significant uncertainties. The results presented here support previous conclusions based on the analysis of the Virgo and Perseus Clusters and agree with the Hitomi measurements. With next-generation observatories like Athena and Lynx, these techniques will be yet more powerful.
Noble Gas Abundance Ratios Indicate the Agglomeration of 67P/Churyumov–Gerasimenko from Warmed-up Ice
Authors: Mousis O. , Ronnet T. , Lunine J. I. , Luspay-Kuti A. , Mandt K. E. , Danger G. , Pauzat F. , Ellinger Y. , Wurz P. , Vernazza P. , Sergeant d’Hendecourt L. Le 
Published: September 2018

Abstract
The origin of cometary volatiles remains a major open question in planetary science. Comets may have either agglomerated from crystalline ices condensed in the protosolar nebula (PSN) or from amorphous ice originating from the molecular cloud and interstellar medium. Here, based on the recent argon, krypton, and xenon measurements performed by the ROSINA mass spectrometer on board the European Space Agency’s Rosetta spacecraft in the coma of 67P/Churyumov–Gerasimenko, we show that these noble gas relative abundances can be explained if the comet’s building blocks formed from a mixture of gas and H2O grains resulting from the annealing of pristine amorphous ice (i.e., originating from the presolar cloud) in the PSN. In this scenario, the different volatiles released during the amorphous-to-crystalline ice phase transition would have been subsequently trapped at lower temperatures in stoichiometric hydrate or clathrate hydrate forms by the crystalline water ice generated by the transition. Once crystalline water was completely consumed by clathration in the ∼25–80 K temperature range, the volatile species remaining in the gas phase would have formed pure condensates at lower temperatures. The formation of clathrates hydrates and pure condensates to explain the noble gas relative abundances is consistent with a proposed interstellar origin of molecular oxygen detected in 67P/Churyumov–Gerasimenko, and with the measured molecular nitrogen depletion in comets.
Critique de la religion, critique de l’économie, et retour
Authors: Balibar Étienne 
Published: September 2018

Une violence généralisée semble coextensive à la mondialisation. La question se pose de savoir quels « croisements » engendrent la régression du politique en deçà des formes qui ont fait l’historicité des siècles passés. Il faut remettre en question le préjugé marxien d’un « achèvement » de la critique du religieux pour affronter le régime de constitution des corps comme corps symboliques et comme corps productifs, soumis à une double expropriation.
Pontifex Maximus versus Kkapitalismus. Laudato si : une encyclique antisystémique
Authors: Löwy Michael 
Published: September 2018

L’élection du Pape François (Bergoglio) est un changement inattendu dans l’orientation de l’Église. Nous en prenons dans cet article pour preuve son encyclique « écologique » Laudato Si , qui dénonce l’actuel « système de relations commerciales et de propriété structurellement pervers » comme responsable des inégalités sociales et de la crise écologique.
De l’organisation citoyenne au marketing : le community organizing comme pratique de régulation de l’autonomie au sein des plateformes d’intermédiation numérique ?
Authors: Peirot Nicolas 
Published: September 2018

Cet article propose une approche communicationnelle de l’instrumentalisation marketing du community organizing dans le cadre du Web 2.0. L’hypothèse principale est que le community organizing constitue un mode émergent de régulation de l’autonomie des utilisateurs pour les plateformes d’intermédiation numérique. Après avoir resitué la notion d’autonomie par rapport aux enjeux économiques des plateformes, nous soulignons les spécificités organisationnelles du community organizing . Cette approche nous conduit à présenter les résultats issus d’une enquête exploratoire. Ces derniers valident partiellement l’idée d’un community organizing comme une régulation autonome. Ils ouvrent la discussion quant à une instrumentalisation politique de ce modèle par les plateformes.
Communauté épistémique et dynamique d’innovation collaborative : l’innovation contrariée au sein des pôles de compétitivité
Authors: Aliouat Boualem , Thiaw Cheikh Abdou Lahad 
Published: September 2018

Notre article s’inscrit dans un courant interactionniste de l’innovation en réseau que sous-tendent des facteurs de « communautarisme épistémique » favorables à l’innovation collaborative. Cette recherche mesure la propension des pôles de compétitivité à favoriser l’innovation entre parties prenantes en identifiant la présence d’une communauté épistémique dans le champ socio-sémantique de ces pôles. Une analyse du pôle « Solutions Communicantes Sécurisées » en région Paca, nous permet de mieux comprendre les ressorts de l’innovation collaborative reposant sur des dispositifs de réduction de la complexité de l’espace de collaboration, et des facteurs de convergence de visions, d’intentions, de comportements et de pratiques.
La prescription d’activité physique par le médecin traitant : l’expérience de Biarritz Côte Basque Sport Santé
Authors: Bauduer Frédéric , Vanz Edson , Guillet Nicolas , Maurice Sylvie 
Published: September 2018

Introduction : L’insuffisance d’activité physique (AP) constitue un problème de santé publique car elle est associée à un risque accru de maladies chroniques et de mortalité prématurée. Nous avons utilisé la prescription d’AP adaptée par le médecin généraliste et encadrée au niveau d’associations sportives pour lutter contre le manque d’AP. Méthodes : L’association Biarritz Côte Basque Sport Santé (BSS) a mis en place depuis mai 2015 une procédure de prescription d’AP sur ordonnance auprès de médecins généralistes volontaires à destination de leurs patients insuffisamment actifs indemnes de pathologie chronique patente. Les personnes sont soit adressées directement à une association sportive où ils sont pris en charge par un éducateur sportif formé, soit passent par le filtre préalable d’un éducateur médico-sportif de BSS qui procède à un entretien motivationnel et une évaluation physique afin de les orienter vers l’AP encadrée la plus adaptée. La prescription d’AP (parmi 15 disciplines) s’effectue pour une durée de 12 semaines au terme de laquelle une évaluation individuelle est pratiquée. Nous partageons ici cette expérience après l’engagement de 200 personnes. Résultats : Quatre-vingt-six médecins exerçant dans 17 communes de la côte basque ont participé à cette expérience. Deux cents personnes ont bénéficié d’une prescription d’AP (27 % d’hommes) d’âge moyen 54 ans (extrêmes : 18-80) ; 20 % des individus ont été directement dirigés par le médecin vers les associations concernées et 80 % sont passés par l’éducateur médico-sportif de BSS. La gymnastique aquatique constitue ici l’AP adoptée par le plus de participants (23 %). Le nombre des clubs adhérents est passé de 7 au début de l’expérience à 25 au moment de cette analyse. 28 éducateurs sportifs ont suivi le dispositif de formation pour accueillir nos participants. Au moment de l’évaluation, 138 sujets sont arrivés au terme de la période de 12 semaines. Parmi eux 90 % ont poursuivi une pratique d’AP auprès d’une association sportive. Discussion : Notre expérience suggère que la prescription d’AP par le médecin traitant auprès d’intervenants formés d’associations sportives est une procédure réalisable à destination des sujets avec insuffisance d’AP. Elle propose l’appui d’une structure intermédiaire, la cellule de BSS, qui permet l’évaluation et l’orientation vers une AP adaptée de chaque participant ainsi qu’un suivi d’observance. Le succès à long terme d’un tel dispositif reste cependant à évaluer.
Incidence et facteurs de risque de l’infection du site opératoire après césarienne dans une maternité de Tunisie
Authors: Merzougui Latifa , Marwen Nedia , Hannachi Hajer , Asma Massoudi , Ben Elhaj Olfa , Waddah Manssouri , Fatnassi Ridha 
Published: September 2018

Objectifs : L’Infection du site opératoire (ISO) est l’une des complications les plus fréquentes après césarienne. Son incidence varie de 3 % à 15 %. Notre objectif était d’estimer l’incidence et de déterminer les facteurs de risque de l’ISO après césarienne dans la maternité universitaire de Kairouan. Méthodes : Étude prospective d’incidence incluant les patientes ayant eu une césarienne entre décembre 2015 et février 2016 à la maternité de Kairouan. Leurs états cliniques étaient surveillés activement (à la consultation externe, aux urgences et à défaut, elles étaient contactées par téléphones) durant les 30 jours postopératoire ; Un modèle de régression logistique multivariée était utilisé pour identifier les facteurs de risque indépendants. Résultats : Parmi les 714 patientes ayant eu une césarienne, 636 d’entre elles (89 %) ont pu être suivies jusqu’au 30 e jour postopératoire. 32 cas d’ISO ont été diagnostiqués donnant une incidence globale de 5 % (IC95 % = 3,3 % ; 6,6 %). La densité d’incidence était de 1,73 pour 1 000 patientes-jour. La majorité des infections (87,5 %) étaient superficielles et 12,5 % ISO étaient de type organe/espace). L’âge a été identifié comme un facteur de risque indépendant de l’ISO (RR = 1,07 pour une augmentation d’un an, IC95 % = 1,007 ; 1,17) alors que le drainage a été identifié comme un facteur protecteur (RR = 0,16, IC95 % = (0,05 ; 0,48). Conclusion : Notre étude a permis d’identifier l’incidence et les facteurs de risque de l’ISO après césarienne. La prévention de ce type d’infection doit être l’une des priorités du système de santé.