bluuebunny/crossref_metadata_2025_split huggingface dataset:
A characterization of the single-peaked single-crossing domain
Authors: Elkind Edith , Faliszewski Piotr , Skowron Piotr 
Published: September 2019

AbstractWe characterize elections that are simultaneously single-peaked and single-crossing (SPSC), by establishing a connection between this domain and that of minimally rich elections, i.e., elections where each candidate is ranked first by at least one voter. Specifically, we show that an election is both single-peaked and single-crossing if and only if it can be obtained from a minimally rich single-crossing election by deleting voters.
On the Relation of Separability, Bandwidth and Embedding
Authors: Csaba Béla , Vásárhelyi Bálint 
Published: September 2019

AbstractIn this paper we construct a class of bounded degree bipartite graphs with a small separator and large bandwidth, thereby showing that separability and bandwidth are not linearly equivalent. Furthermore, we also prove that graphs from this class are spanning subgraphs of graphs with minimum degree just slightly aboven / 2, even though their bandwidth is large.
In silico and expression analyses of fasciclin-like arabinogalactan proteins reveal functional conservation during embryo and seed development
Authors: Costa Mário , Pereira Ana Marta , Pinto Sara Cristina , Silva Jessy , Pereira Luís Gustavo , Coimbra Sílvia 
Published: September 2019

Key message
The fasciclin-like arabinogalactan proteins organization into four groups is conserved and may be related to specific roles in developmental processes across angiosperms.

Abstract
Fasciclin-like arabinogalactan proteins (FLAs) are a subclass of arabinogalactan proteins (AGPs), which contain fasciclin-like domains in addition to typical AGP domains. FLAs are present across all embryophytes, and despite their low overall sequence similarity, conserved regions that define the fasciclin functional domain (FAS) have been identified, suggesting that the cell adhesion property is also conserved. FLAs in Arabidopsis have been organized into four subgroups according to the number and distribution of functional domains. Recent studies associated FLAs with cell wall-related processes where domain organization seemed to be related to functional roles. In Arabidopsis, FLAs containing a single FAS domain were found to be important for the integrity and elasticity of the plant cell wall matrix, and FLAs with two FAS domains and two AGP domains were found to be involved in maintaining proper cell expansion under salt stress conditions. The main purpose of the present work was to elucidate the expression pattern of selected FLA genes during embryo and seed development using RT-qPCR. AtFLA8 and AtFLA10, two Arabidopsis genes that stood out in previous microarray studies of embryo development, were further examined using promoter-driven gene reporter analyses. We also studied the expression of cork oak FLA genes and found that their expression partially parallels the expression patterns of the putative AtFLA orthologs. We propose that the functional organization of FLAs is conserved and may be related to fundamental aspects of embryogenesis and seed development across angiosperms. Phylogenetic studies were performed, and we show that the same basic four-subgroup organization described for Arabidopsis FLA gene classification is valid for most Arabidopsis FLA orthologs of several plant species, namely poplar, corn and cork oak.
Analysis and quantification of bone healing after open wedge high tibial osteotomy
Authors: Nemecek Elena , Chiari Catharina , Valentinitsch Alexander , Kainberger Franz , Hobusch Gerhard , Kolb Alexander , Hirtler Lena , Trost Carmen , Vukicevic Slobodan , Windhager Reinhard 
Published: September 2019

Summary

Background
The aim of this study was to analyze radiographic imaging techniques and to quantify bone ossification in the osteotomy gap after high tibial osteotomy.

Material and methods
Study phase 1: high tibial osteotomy was performed on six lower extremities of human body donors and experimental X‑rays and computed tomography (CT) scans were applied. Different techniques were evaluated by three specialists for best representation of the osteotomy gap.
Study phase 2: optimized radiological techniques were used for follow-up on 12 patients. The radiographs were examined by 3 specialists measuring 10 different parameters. The CT scans were analyzed with semiautomatic computer software for quantification of bone ossification.

Results
The osteotomy gap was best represented in 30° of flexion in the knee and 20° internal rotation of the leg. There were significant changes of the medial width over time (p < 0.019) as well as of the length of fused osteotomy, the Schröter score, sclerosis, trabecular structure and zone area measurements. Sclerosis, medial width of the osteotomy and area measurements were detected as reproducible parameters. Bone mineral density was calculated using CT scans, showing a significantly higher value 12 weeks postoperatively (112.5 mg/cm3) than at baseline (54.6 mg/cm3). The ossification of the gap was visualized by color coding.

Conclusion
Sclerosis and medial width of the osteotomy gap as well as area measurements were determined as reproducible parameters for evaluation of bone healing. Quantification of bone ossification can be calculated with CT scans using a semiautomatic computer program and should be used for research in bone healing.
Smart home technology—comparing householder expectations at the point of installation with experiences 1 year later
Authors: Oliveira Luis , Mitchell Val , May Andrew 
Published: September 2019

AbstractThis study, with 19 households, set out to analyse the expected benefits and anticipated challenges to the introduction of smart home technology (SHT), and to compare these to post-use experiences after living with the technology for 1 year. Contextual interviews were undertaken with householders during the installation of a range of SHT, and again approximately 1 year later, when householders had the option to keep the technology or have some or all of it removed. This identified whether initial expectations were met, whether initial concerns persisted and whether new issues, concerns, and benefits (that had not been initially anticipated) arose after an extended period of use. Initial expectations from all households were high—related to comfort, convenience, improved control, energy demand reduction, and integration of technologies. There were also many initial concerns, including reliability, usability, and how these systems would be ‘domesticated’ to fit existing routines. After living with the systems for 1 year, many expectations were met, but the added value (and hence the match between expectations and reality) was higher for households with varied routines and large, partially occupied houses. Some of the anticipated challenges—such as concerns over aesthetics—largely disappeared, issues to do with the awkward location of network components persisted and new issues arose relating to the usability of some components and the time and effort required to configure them. Recommendations are given to maximise the added value that SHT can provide to householders.
Diagnostic performance of two molecular assays for the detection of vaginitis in symptomatic women
Authors: Thompson Alexandra , Timm Karen , Borders Noelle , Montoya Liz , Culbreath Karissa 
Published: September 2019

Abstract
The three main causes of vaginitis are bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and trichomoniasis (TV). Two multiplex assays are commercially available for detection of DNA from organisms associated with vaginitis: BD Affirm™ VPIII Microbial Identification Test (Affirm) and BD MAX™ Vaginal Panel (MAX VP). Here, the performance of MAX VP was compared to that of Affirm, which was considered the standard of care. Four vaginal swabs were collected from each subject with the following: BD Affirm™ VPIII Ambient Temperature Transport System (ATTS), BD MAX™ UVE Specimen Collection Kit, Hologic Aptima® Vaginal Swab Specimen Collection Kit, and BD ESwab™ collection and transport system (ESwab). Candida culture, Gram stain followed by Nugent scoring, and the Hologic Aptima® Trichomonas vaginalis assay were used for discordant analysis. Results were considered true positive if there were at least two tests positive for any vaginitis target. A total of 200 symptomatic women were evaluated in the study. The sensitivity and specificity of MAX VP for BV was 96.2% and 96.1%, respectively, compared to 96.2% and 81.6% for Affirm. The sensitivity and specificity of MAX VP for Candida spp. was 98.4% and 95.4%, respectively, compared to 69.4% and 100% for Affirm. MAX VP and Affirm showed 100% concordance for detection of TV. These results demonstrate improved accuracy of MAX VP compared to Affirm for the detection of BV and Candida spp. and no difference for detection of TV between the two tests.
Computational modeling of therapy on pancreatic cancer in its early stages
Authors: Chen Jiao , Weihs Daphne , Vermolen Fred J. 
Published: September 2019

AbstractMore than eighty percent of pancreatic cancer involves ductal adenocarcinoma with an abundant desmoplastic extracellular matrix surrounding the solid tumor entity. This aberrant tumor microenvironment facilitates a strong resistance of pancreatic cancer to medication. Although various therapeutic strategies have been reported to be effective in mice with pancreatic cancer, they still need to be tested quantitatively in wider animal-based experiments before being applied as therapies. To aid the design of experiments, we develop a cell-based mathematical model to describe cancer progression under therapy with a specific application to pancreatic cancer. The displacement of cells is simulated by solving a large system of stochastic differential equations with the Euler–Maruyama method. We consider treatment with the PEGylated drug PEGPH20 that breaks down hyaluronan in desmoplastic stroma followed by administration of the chemotherapy drug gemcitabine to inhibit the proliferation of cancer cells. Modeling the effects of PEGPH20 + gemcitabine concentrations is based on Green’s fundamental solutions of the reaction–diffusion equation. Moreover, Monte Carlo simulations are performed to quantitatively investigate uncertainties in the input parameters as well as predictions for the likelihood of success of cancer therapy. Our simplified model is able to simulate cancer progression and evaluate treatments to inhibit the progression of cancer.
Sexual dichromatism of the Blue-throated Starfrontlet, Coeligena helianthea, hummingbird plumage
Authors: Sosa Juliana , Parra Juan L. , Stavenga Doekele G. , Giraldo Marco A. 
Published: September 2019

AbstractAmong the many richly coloured birds, hummingbirds with their brilliant colouration are outstanding. We studied the plumage of male and female Blue-throated Starfrontlet,Coeligena helianthea, which exhibits a marked sexual dichromatism. The wide diversity of coloured feathers (blue, purple, golden, green, red) makes it an attractive species to investigate the structural basis of the colouration and to study the connection between the displayed colours and the perception by conspecifics. We analysed the optical properties of the feather barbules, applying spectrophotometry, scatterometry, and electron microscopy. Using the anatomical results, the spectral data can be interpreted by optical modelling. The reflectance spectra of the feathers of maleC. heliantheastrikingly overlap with the spectral sensitivities of bird photoreceptors, which suggests that the feather and photoreceptor spectra are tuned.
Variability of cone parameters and scale morphology in the black alder (Alnus glutinosa L.) in the context of seed extraction
Authors: Aniszewska Monika , Tulska Ewa , Żurawska Katarzyna 
Published: September 2019

Abstract
In this paper, the results of research on the variability of black alder cones (Alnus glutinosa L.) ware presented. The research was carried out for two, significantly different, batches of cones. Basic size parameters and mass were measured. The shape of the cone was determined, and it was described with the fourth-degree polynomial. The surface area and volume of the cone were calculated using the forming curve and formulas for solids: barrel and cylinder. The parameters of cones—shape surface area and volume—were analyzed. It was found that for alder cones (from the researched origins), the average volumes calculated from the barrel formula are 1701 mm3 and 1162 mm3, and the areas calculated from the cylinder formula are 807 mm2 and 597 mm2. The structure of the inner and outer sides of scales was examined using a scanning electron microscope. Using the MultiScanBase v. 18.03 program, the elements of husk structure that could affect the efficiency of seeds extraction were measured. The results of the research can be used to program the process of seeds extraction from alder cones in commercial installations.
The Investigation on Flow Behavior of Powder Metallurgy Ti-10V-2Fe-3Al Alloy Using the Prasad Stability Criterion
Authors: Zyguła Krystian , Wojtaszek Marek , Lypchanskyi Oleksandr , Śleboda Tomasz , Korpała Grzegorz , Prahl Ulrich 
Published: September 2019

Abstract
The hot deformation behavior of Ti-10V-2Fe-3Al alloy obtained by the powder metallurgy (PM) method was investigated. Material for the research was produced by blending of elemental powders followed by uniaxial hot pressing. Thermomechanical tests of Ti-10V-2Fe-3Al compacts were carried out to determinate the stress-strain relationships at the temperature range of 800 °C to 1000 °C and strain rate between 0.01 and 10 s−1. Based on the dynamic material model (DMM) theory, processing maps at constant strain value were developed using data obtained from hot compression tests. The processing maps were elaborated for the final strain value, which was 0.9, and with flow instability criterion domains applied to it. Two critical regions associated with the flow behavior of the investigated material were revealed. Microstructural changes during hot deformation at various temperatures and strain rates were discussed. The correlation between calculated efficiency of power dissipation, flow instability criterion, and microstructure evolution was determined. The presence of defects was confirmed in regions predicted by the instability maps. The microstructure of the investigated alloy, corresponding to the high efficiency of power dissipation characterized by the occurrence of dynamic recrystallization (DRX) phenomena, was also shown. Additionally, average hardness values in relation to variable process parameters were designated. Based on the conducted studies and analysis, processing windows for Ti-10V-2Fe-3Al alloy compacts were proposed.
Quantification of Quartz Reefs and Mafic Dykes of Bundelkhand, Craton, Central India: A Study Based on Spatial and Fractal Analysis
Authors: Das Dip , Mondal Tridib Kumar , Hossain Md. Sakawat 
Published: September 2019

ABSTRACT
The geological structures and their 2D geometrical relationships are often quantified using spatial and fractal techniques. In this study, quartz reefs and dykes from Bundelkhand craton of central India are investigated using spatial and fractal analysis to quantify the spatial relationship and establish the deformational events. The Bundelkhand craton comprises of massive granite batholiths, associated with extensive hydrothermal activities that led to the formation of numerous quartz reefs mostly in NE-SW and NW-SE directions. The area is also replete with NW-SE and NE-SW oriented mafic dykes, which are assumed to have formed during late stage crustal rejuvenation.
The spatial analysis suggests that each set of reefs and dykes are not the result of random processes (high Z score and low P-values). The fractal analyses also suggest, that there are at least two deformational events that led to the formation of quartz reefs and dykes independently in the Bundelkhand craton. The anisotropy of fractal dimension study validates the results obtained from the spatial statistical analysis. This study has provided important informations related to the number of deformational events and deformation localization in the study area.
Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959–2016
Authors: Acosta Enrique , Hallman Stacey A. , Dillon Lisa Y. , Ouellette Nadine , Bourbeau Robert , Herring D. Ann , Inwood Kris , Earn David J. D. , Madrenas Joaquin , Miller Matthew S. , Gagnon Alain 
Published: September 2019

AbstractThis study examines the roles of age, period, and cohort in influenza mortality trends over the years 1959–2016 in the United States. First, we use Lexis surfaces based on Serfling models to highlight influenza mortality patterns as well as to identify lingering effects of early-life exposure to specific influenza virus subtypes (e.g., H1N1, H3N2). Second, we use age-period-cohort (APC) methods to explore APC linear trends and identify changes in the slope of these trends (contrasts). Our analyses reveal a series of breakpoints where the magnitude and direction of birth cohort trends significantly change, mostly corresponding to years in which important antigenic drifts or shifts took place (i.e., 1947, 1957, 1968, and 1978). Whereas child, youth, and adult influenza mortality appear to be influenced by a combination of cohort- and period-specific factors, reflecting the interaction between the antigenic experience of the population and the evolution of the influenza virus itself, mortality patterns of the elderly appear to be molded by broader cohort factors. The latter would reflect the processes of physiological capital improvement in successive birth cohorts through secular changes in early-life conditions. Antigenic imprinting, cohort morbidity phenotype, and other mechanisms that can generate the observed cohort effects, including the baby boom, are discussed.
Het klinisch beloop bij gemetastaseerd prostaatcarcinoom
Authors: ter Haar Ronald W. , Boevé Liselotte M. S. , Hillenius Jasper J. , van Andel George 
Published: September 2019

SamenvattingVan de patiënten met een prostaatcarcinoom heeft 16% bij het stellen van de diagnose al botmetastasen. Nog eens 30% van de patiënten ontwikkelt later botmetastasen. Dit artikel biedt een overzicht van de literatuur over het klinisch beloop van het gemetastaseerde prostaatcarcinoom. Ook worden de resultaten gepresenteerd van twee Nederlandse studies naar het klinisch beloop bij prostaatcarcinoom. De meest frequent voorkomende relevante klinische problemen zijn: fractuur (10–15%), (in)complete dwarslaesie (10–15%), blaasontledigingsstoornissen waarvoor CIC, CAD, SP of een TURP (25%), symptomatische hydronefrose door obstructie van de distale ureter waarvoor een nefrodrain of JJ noodzakelijk is (5%), anemie waarvoor bloedtransfusie(s) nodig is (zijn) (35%), ziekenhuisopname vanwege aan het prostaatcarcinoom gerelateerde problemen (75%) en palliatieve bestraling(en) in verband met pijnlijke botmetastasen (55%). Tot slot wordt op hoofdlijnen een overzicht gegeven van de meest gangbare behandelingen van voornoemde problemen.
Combat as an Interpersonal Synergy: An Ecological Dynamics Approach to Combat Sports
Authors: Krabben Kai , Orth Dominic , van der Kamp John 
Published: September 2019

Abstract
In combat sports, athletes continuously co-adapt their behavior to that of the opponent. We consider this interactive aspect of combat to be at the heart of skilled performance, yet combat sports research often neglects or limits interaction between combatants. To promote a more interactive approach, the aim of this paper is to understand combat sports from the combined perspective of ecological psychology and dynamic systems. Accordingly, combat athletes are driven by perception of affordances to attack and defend. Two combatants in a fight self-organize into one interpersonal synergy, where the perceptions and actions of both athletes are coupled. To be successful in combat, performers need to manipulate and take advantage of the (in)stability of the system. Skilled performance in combat sports therefore requires brinkmanship: combatants need to be aware of their action boundaries and purposefully act in meta-stable regions on the limits of their capabilities. We review the experimental literature to provide initial support for a synergetic approach to combat sports. Expert combatants seem able to accurately perceive action boundaries for themselves and their opponent. Local-level behavior of individual combatants has been found to lead to spatiotemporal synchronization at the global level of a fight. Yet, a formal understanding of combat as a dynamic system starting with the identification of order and control parameters is still lacking. We conclude that the ecological dynamics perspective offers a promising approach to further our understanding of skilled performance in combat sports, as well as to assist coaches and athletes to promote optimal training and learning.
Fluorescent Silicon Nanorods-Based Nanotheranostic Agents for Multimodal Imaging-Guided Photothermal Therapy
Authors: Cui Mingyue , Liu Sangmo , Song Bin , Guo Daoxia , Wang Jinhua , Hu Guyue , Su Yuanyuan , He Yao 
Published: September 2019

Abstract
The utilization of diagnosis to guide/aid therapy procedures has shown great prospects in the era of personalized medicine along with the recognition of tumor heterogeneity and complexity. Herein, a kind of multifunctional silicon-based nanostructure, i.e., gold nanoparticles-decorated fluorescent silicon nanorods (Au@SiNRs), is fabricated and exploited for tumor-targeted multimodal imaging-guided photothermal therapy. In particular, the prepared Au@SiNRs feature high photothermal conversion efficiency (~ 43.9%) and strong photothermal stability (photothermal performance stays constant after five-cycle NIR laser irradiation), making them high-performance agents for simultaneously photoacoustic and infrared thermal imaging. The Au@SiNRs are readily modified with targeting peptide ligands, enabling an enhanced tumor accumulation with a high value of ~ 8.74% ID g−1. Taking advantages of these unique merits, the Au@SiNRs are superbly suitable for specifically ablating tumors in vivo without appreciable toxicity under the guidance of multimodal imaging. Typically, all the mice treated with the Au@SiNRs remain alive, and no distinct tumor recurrence is observed during 60-day investigation.
Asteroseismology of solar-type stars
Authors: García Rafael A. , Ballot Jérôme 
Published: September 2019

AbstractUntil the last few decades, investigations of stellar interiors had been restricted to theoretical studies only constrained by observations of their global properties and external characteristics. However, in the last 30 years the field has been revolutionized by the ability to perform seismic investigations of stellar interiors. This revolution begun with the Sun, where helioseismology has been yielding information competing with what can be inferred about the Earth’s interior from geoseismology. The last two decades have witnessed the advent of asteroseismology of solar-like stars, thanks to a dramatic development of new observing facilities providing the first reliable results on the interiors of distant stars. The coming years will see a huge development in this field. In this review we focus on solar-type stars, i.e., cool main-sequence stars where oscillations are stochastically excited by surface convection. After a short introduction and a historical overview of the discipline, we review the observational techniques generally used, and we describe the theory behind stellar oscillations in cool main-sequence stars. We continue with a complete description of the normal mode analyses through which it is possible to extract the physical information about the structure and dynamics of the stars. We then summarize the lessons that we have learned and discuss unsolved issues and questions that are still unanswered.