bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effects of Mothers' Protective Parenting and Alcohol Use on Emerging Adults' Alcohol Use: Testing Indirect Effects Through Prototype Favorability Among African American Youth
Authors: Cleveland Michael J. , Turrisi Rob , Gibbons Frederick X. , Gerrard Meg , Marzell Miesha 
Published: June 2018

BackgroundWe examined how mothers' protective parenting and alcohol use influenced changes in offspring's heavy drinking among a sample of African American youth. The conceptual model also tested indirect effects of mothers' behaviors, through changes in the youths' social images (i.e., prototypes) of heavy drinkers, derived from the prototype willingness (PW) model.MethodsParticipants were 686 emerging adults (55% female) from the Family and Community Health Study (FACHS), an ongoing prospective study of African American families. Three waves of FACHS data were used as follows: T3 during 10th grade (M age = 16.3 years), T4 shortly after high school (M age = 19.4 years), and T5 3 years later (M age = 22.1 years). Mothers' self‐reports of protective parenting and alcohol use were assessed at T4. Two separate path models tested the study hypotheses. The first model specified direct and indirect effects of mothers' protective parenting and alcohol use. The second model added interaction terms between the protective parenting behaviors and mothers' alcohol use. The analyses were first conducted using the full sample and then repeated separately for female and male participants.ResultsMaternal alcohol use had a positive and direct effect on offspring's alcohol use. Mothers' endorsement of alcohol‐related rules inhibited normative increases in the favorability of the offspring's social image of heavy drinkers (prototype) while her warmth was positively related to these increases. Maternal alcohol use amplified the positive association between mothers' warmth and the daughters' increased drinking. For sons, maternal alcohol use increased the positive association between alcohol‐related rules and increased prototype favorability.ConclusionsResults indicated clear gender differences in how mothers' behaviors influence her offspring's alcohol use during the transition to emerging adulthood. Interventions that target culturally specific risk and protective factors within the family environment are needed to reduce health disparities among this vulnerable population of youth.
Enough and as Good: A Formal Model of Lockean First Appropriation
Authors: Kogelmann Brian , Ogden Benjamin G. 
Published: June 2018

AbstractIn developing a theory of the first appropriation of natural resources from the state of nature, John Locke tells us that persons must leave “enough and as good” for others. Detailing exactly what this restriction requires divides right and left libertarians. Briefly, right libertarians interpret “enough and as good” as requiring no or very minimal restrictions on the first appropriation of natural resources, whereas left libertarians interpret “enough and as good” as requiring everyone to be entitled to an equal share of unappropriated resources, able to claim no more beyond this equal share. This article approaches the right versus left libertarian debate by developing a formal model that examines the welfare properties of different interpretations of the Lockean proviso. The model shows that underlying philosophical justifications for left libertarianism, when plausible assumptions hold, will actually be better served by a right libertarian proviso rather than a left libertarian one.
The importance of ecological memory for trophic rewilding as an ecosystem restoration approach
Authors: Schweiger Andreas H. , Boulangeat Isabelle , Conradi Timo , Davis Matt , Svenning Jens‐Christian 
Published: June 2018

ABSTRACTIncreasing human pressure on strongly defaunated ecosystems is characteristic of the Anthropocene and calls for proactive restoration approaches that promote self‐sustaining, functioning ecosystems. However, the suitability of novel restoration concepts such as trophic rewilding is still under discussion given fragmentary empirical data and limited theory development. Here, we develop a theoretical framework that integrates the concept of ‘ecological memory’ into trophic rewilding. The ecological memory of an ecosystem is defined as an ecosystem's accumulated abiotic and biotic material and information legacies from past dynamics. By summarising existing knowledge about the ecological effects of megafauna extinction and rewilding across a large range of spatial and temporal scales, we identify two key drivers of ecosystem responses to trophic rewilding: (i) impact potential of (re)introduced megafauna, and (ii) ecological memory characterising the focal ecosystem. The impact potential of (re)introduced megafauna species can be estimated from species properties such as lifetime per capita engineering capacity, population density, home range size and niche overlap with resident species. The importance of ecological memory characterising the focal ecosystem depends on (i) the absolute time since megafauna loss, (ii) the speed of abiotic and biotic turnover, (iii) the strength of species interactions characterising the focal ecosystem, and (iv) the compensatory capacity of surrounding source ecosystems. These properties related to the focal and surrounding ecosystems mediate material and information legacies (its ecological memory) and modulate the net ecosystem impact of (re)introduced megafauna species. We provide practical advice about how to quantify all these properties while highlighting the strong link between ecological memory and historically contingent ecosystem trajectories. With this newly established ecological memory–rewilding framework, we hope to guide future empirical studies that investigate the ecological effects of trophic rewilding and other ecosystem‐restoration approaches. The proposed integrated conceptual framework should also assist managers and decision makers to anticipate the possible trajectories of ecosystem dynamics after restoration actions and to weigh plausible alternatives. This will help practitioners to develop adaptive management strategies for trophic rewilding that could facilitate sustainable management of functioning ecosystems in an increasingly human‐dominated world.
Altitudinal migration: ecological drivers, knowledge gaps, and conservation implications
Authors: Hsiung An C. , Boyle W. Alice , Cooper Robert J. , Chandler Richard B. 
Published: June 2018

ABSTRACTAnimal migration has been the subject of intensive research for more than a century, but most research has focused on long‐distance rather than short‐distance migration. Altitudinal migration is a form of short‐distance migration in which individuals perform seasonal elevational movements. Despite its geographic and taxonomic ubiquity, there is relatively little information about the intrinsic and extrinsic factors that influence altitudinal migratory behaviour. Without this information, it is difficult to predict how rapid environmental changes will affect population viability of altitudinal migrants. To synthesize current knowledge, we compiled literature on altitudinal migration for all studied taxa, and identified the leading hypotheses explaining this behaviour. Studies of animal altitudinal migration cover many taxonomic lineages, with birds being the most commonly studied group. Altitudinal migration occurs in all continents except for Antarctica, but about a third of the literature focused on altitudinal migration in North America. Most research suggests that food and weather are the primary extrinsic drivers of altitudinal migration. In addition, substantial individual‐level variation in migratory propensity exists. Individual characteristics that are associated with sex, dominance rank, and body size explain much of the variation in migratory propensity in partially migratory populations, but individual‐level correlates are poorly known for most taxa. More research is needed to quantify the effects of habitat loss, habitat fragmentation, and climate change on altitudinal migrants. Demographic studies of individually marked populations would be particularly valuable for advancing knowledge of the cascading effects of environmental change on migratory propensity, movement patterns, and population viability. We conclude our review with recommendations for study designs and modelling approaches that could be used to narrow existing knowledge gaps, which currently hinder effective conservation of altitudinal migratory species.
Population Pharmacokinetic and Exposure–dizziness Modeling for a Metabotropic Glutamate Receptor Subtype 5 Negative Allosteric Modulator in Major Depressive Disorder Patients
Authors: Cosson Valérie , Schaedeli‐Stark Franziska , Arab‐Alameddine Mona , Chavanne Clarisse , Guerini Elena , Derks Michael , Mallalieu Navita L. 
Published: June 2018

AbstractDizziness, the most frequently observed adverse event in patients with major depressive disorder, was observed with basimglurant, a selective, orally active metabotropic glutamate receptor subtype 5 negative allosteric modulator. The potential relationship between dizziness and basimglurant exposure was explored. The pharmacokinetics of basimglurant was characterized with nonlinear mixed effects modeling using data from 288 trial participants enrolled in five clinical trials. The pharmacokinetics of basimglurant after daily oral administration of a modified release formulation was best described by a two‐compartment disposition model with a transit compartment, lag time for the absorption, and first‐order elimination. The largest covariate effects were the effect of smoking and male gender on apparent clearance followed by the effect of body weight on distribution volumes. Clearance was twofold higher in smokers and 40% higher in males. A logistic regression model showed a statistically significant correlation between basimglurant Cmax and incidence of dizziness. An increased risk of dizziness is predicted with increasing doses.
Effect of Dose and 5α‐Reductase Inhibition on the Circulating Testosterone Metabolite Profile of Men Administered Oral Testosterone
Authors: Basit Abdul , Amory John K. , Prasad Bhagwat 
Published: June 2018

AbstractDevelopment of an oral testosterone therapy has proven extremely challenging because of extensive and variable first‐pass metabolism. We investigated the in vivo metabolism of testosterone with increasing oral doses of testosterone, both alone and with the co‐administration of dutasteride (5α‐reductase inhibitor) by liquid‐chromatography tandem mass spectrometry (LC‐MS/MS). In eugonadal men prior to dosing, the circulating concentration of testosterone, androstenedione, etiocholanolone‐glucuronide, and androsterone‐glucuronide was 8.6, 20.9, 9.1, and 55.3%, respectively, of the total testosterone‐related species, whereas testosterone‐glucuronide was ∼1%. When testosterone was dosed orally to men with experimental hypogonadism, a proportion of testosterone‐glucuronide increased to 13%. Dutasteride treatment significantly decreased levels of androsterone and its metabolites. This work reveals extensive metabolism of orally dosed testosterone to androsterone glucuronide via androstenedione, with testosterone‐glucuronide appearing to be the second most important metabolite. This information is of importance in the development of an effective oral testosterone therapy and may have implications for testosterone doping research.
Failing to meet the needs of generations of care home residents with diabetes: a review of the literature and a call for action
Authors: Sinclair A. J. , Gadsby R. , Abdelhafiz A. H. , Kennedy M. 
Published: June 2018

AbstractIn residential care homes and aged‐care facilities globally, between one in three and one in four residents may have diabetes, an often complex highly co‐morbid illness that leads to frailty, dependency, disability and reduced life expectancy. Residents with diabetes also have a high risk of hypoglycaemia, avoidable hospital admissions, and represent one of the most difficult challenges to health professionals and care staff in optimizing their diabetes and medical care. This detailed review examines the literature relating to care home diabetes over the last 25 years to assess what has been achieved in characterizing residents with diabetes, and what we know about the various but limited intervention studies that have been carried out internationally. The guidance and guidelines that have been published to assist clinicians in planning effective and safe care for this rather vulnerable group of people with diabetes are also reviewed. The review presents the first diagrammatic representation of a likely physiological cascade depicting the mainly irreversible functional decline a resident with diabetes might experience, provides modern principles of care for each resident with diabetes, and identifies what priority recommendations are required to be implemented if diabetes care is to improve. The review concludes that action is required since diabetes care still remains fragmented, sub‐optimal, and in need of investment, otherwise care home residents with diabetes will continue to have their needs unfulfilled.
Strategies for non‐EEG seizure detection and timing for alerting and interventions with tonic–clonic seizures
Authors: Gutierrez Erie G. , Crone Nathan E. , Kang Joon Y. , Carmenate Yaretson I. , Krauss Gregory L. 
Published: June 2018

SummarySudden unexpected death in epilepsy (SUDEP) is a common cause of death in epilepsy and frequently occurs following generalized tonic–clonic seizures (GTCS). Non–electroencephalography (EEG) seizure detection systems using mobile sensor devices permit caregivers to assist patients during seizures and may reduce risks for complications of seizures such as injuries and SUDEP. We review changes in accelerometry, electrodermal activity, and heart rate associated with tonic–clonic seizures and their use in detection systems, including multimodal detectors. We reviewed current and past publications reporting data on linkage between GTCS, post‐ictal generalized EEG suppression (PGES), and ventilatory dysfunction. The timing and duration of postictal immobility and respiratory dysfunction associated with convulsions help identify which patients might benefit the most from seizure monitoring and from benchmarks for the timing of seizure detection, caregiver alerting, and interventions.
COALITION BARGAINING IN REPEATED GAMES
Authors: Polanski Arnold , Vega‐Redondo Fernando 
Published: June 2018

AbstractWe consider an intertemporal framework where different coalitions interact repeatedly over time.Boththe terms of trade and the endogenous cooperation structure are characterized, in a protocol‐free manner, when:A coalition is formed with positive probability if, and only if, the shares obtained by its members weakly exceed their respective share expectations.Each matched coalition distributes the entire surplus among its members.Members of any coalition are treated symmetrically with respect to their share expectations.We show, in particular, that the cooperation structure and the shares are unique when the game ends each date with vanishing probability.
ZOOMING IN ON AMBIGUITY ATTITUDES
Authors: Baillon Aurélien , Emirmahmutoglu Aysil 
Published: June 2018

AbstractEmpirical studies of ambiguity attitudes to date have focused on events of moderate likelihood. Extrapolation to rare events requires caution. In an Ellsberg‐like experiment with very unlikely events, we measured ambiguity attitudes with neither assumptions on subjects' beliefs nor restrictions to specific ambiguity models. Very unlikely events were overweighted, being weighted more strongly in isolation than when part of larger events. Using latent profile analysis, we classified the subjects in terms of deviations from ambiguity neutrality. One third behaved close to ambiguity neutrality. The others exhibited overweighting of rare events. Such behavior can lead to money‐pump situations.
Two‐stage processing of salmon backbones to obtain high‐quality oil and proteins
Authors: Slizyte Rasa , Mozuraityte Revilija , Remman Tore , Rustad Turid 
Published: June 2018

SummaryTraditional processing technologies for fish by‐products containing significant amounts of oils usually either give high amounts of oil or maximised solubilisation of proteins. Due to lower yields and insufficient quality, the proteins or the oil is considered as secondary products. The proposed concept combines a gentle thermal separation of oil followed by enzymatic hydrolysis of the remaining protein‐rich fraction. The first stage, thermal treatment (40 °C) of fresh salmon backbones, separated up to 85% of the oil from the raw material and gave high‐quality oil (PV = 0.2 ± 0.0 meq kg−1, 0.16 ± 0.05% free fatty acids). Separation of a significant part of the oil gave reduced mass flow into the enzymatic stage, which then requires less enzymes and reduced energy consumption. Among the tested enzymes: Trypsin, Corolase PP and Mixture of Papain and Bromelain gave the highest yield of fish protein hydrolysates (FPH), while use of Protamex and Corolase PP resulted in FPH with the best sensory properties leading to the lowest bitterness.
An implementation of remote laboratory for secondary science education
Authors: Tho S.W. , Yeung Y.Y. 
Published: June 2018

AbstractThis paper reports our classroom implementation of a new remote laboratory (RL) system, which was developed by using innovative ideas and methods for applying technology‐enhanced learning to secondary school science education (Grades 7–9 or Ages 12–14). The newly developed RL system, which involves 8 remote experiments, was tested with 32 secondary school students from a local public school in order to evaluate its usability, learning, and their perception. The present study was carried out by using a mixed research method, including a questionnaire survey (open‐ended questions) and interviews. The corresponding research tools were specifically developed to collect data on students' perceptions and the implementation issues of the RL system. The survey results revealed that there was no major refinement required for the RL system, which was good enough for further adoption in secondary science education because its methods used to conduct online experiments could (a) extend/enhance the existing practices (with virtual/simulation experiments only) of e‐learning and (b) largely induce students' favourable views and perceptions in their own learning. Besides, negative comments and suggestions for improvement were purposely collected during a follow‐up period with an aim to pinpoint any ways in which the RL system and its design could be refined. They turned out to be very minor and easily fixed, and so the refined RL system is educationally suitable for use in laboratory activities and demonstrations to enhance the learning and teaching of science within and outside the secondary school environment.
“Address me personally!”: On the role of language styles in a MOOC
Authors: Riehemann J. , Jucks R. 
Published: June 2018

AbstractIf learning materials are presented in either a conversational or formal language style, people will process them differently. This study reports an experiment in which 64 high school students watched an educational video in a massive open online course scenario in which the instructions were phrased either conversationally or formally. The video demonstrated and explained the psychological McGurk effect. After watching the video, participants performed a transfer task. Learning outcomes were assessed and answers were analysed by using Linguistic Inquiry and Word Count. Results showed better learning outcomes for participants in the conversational (vs. formal) condition. Participants in the formal (vs. conversational) condition referred more to others in their answers. Implications for the design of massive open online courses are discussed.
DOES MANAGERIAL OPPORTUNISM EXPLAIN THE DIFFERENTIAL PRICING OF LEVEL 3 FAIR VALUE ESTIMATES?
Authors: Robinson Dahlia , Smith Thomas , Valencia Adrian 
Published: June 2018

AbstractUsing hand‐collected Level 3 data, we find that banks near key capital ratios report higher unrealized gains in Level 3 assets, consistent with managers using Level 3 valuations to boost capital ratios. Additionally, we document an incremental pricing discount for Level 3 assets among these firms, suggesting that the pricing discount observed by prior research may not be entirely due to measurement error inherent in Level 3. Furthermore, we observe that this opportunistic behavior diminishes under the new Financial Accounting Standards Board disclosure regime, suggesting that the expanded disclosures may increase the value relevance and reliability of fair value measurements.
The Changing Complexion of American Congregations
Authors: Dougherty Kevin D. , Emerson Michael O. 
Published: June 2018

AbstractThe only constant in life is change, or so goes the familiar refrain. But when it comes to research on multiracial congregations, studying change has largely been overlooked. Questions loom about the changing prevalence, leadership, and composition of racially diverse congregations. Using three waves of data from the National Congregations Study (1998, 2006, and 2012), we offer an overarching examination of racial composition in U.S. congregations across approximately 15 years. Both the percentage of multiracial congregations and the amount of racial/ethnic diversity in congregations have increased. The increase has been most dramatic in Protestant churches. In addition, blacks are more common in the pulpit and the pews of America's multiracial congregations than they were in the past. Blacks now surpass Latinos as the group most likely to worship with whites in multiracial congregations. Location and religious tradition continue to be influential factors in a congregation's racial diversity, but the significance of several congregational characteristics have changed over time. We discuss the implications of these findings.
Multitype Recharge Facility Location for Electric Vehicles
Authors: Zhang Xiang , Rey David , Waller S. Travis 
Published: June 2018

AbstractThe motivation of this study is to minimize the system‐level travel time costs and greenhouse emissions, which include tailpipe emissions by internal combustion engine vehicles (ICEVs) and smokestack emissions indirectly caused by electric vehicles (EVs), while satisfying EVs’ replenishment need in transport networks subject to financial restraints for infrastructure development. In this study, we address recharge facility locations of EVs, where two types of recharge services are taken into account, that is, traditional charging stations and modern charging lanes. The multitype recharge facility location problem is formulated by employing the bilevel framework of the network design problem. In the lower‐level program, the mixed‐vehicular traffic assignment problem with en‐route multitype recharge is employed, which accounts for both ICEVs and EVs with various driving ranges. The upper‐level program aims to minimize the total system travel costs by selecting the optimal solution from a set of infrastructure design options considering both expansions of road capacities and provisions of multitype recharge facilities for EVs. In the algorithmic framework, we propose a tailored metaheuristic to solve medium to large instances. Systematic evaluation is conducted to test the efficacy of the proposed approach. The results highlight the impacts of traffic composition, distance ranges of EVs, budget levels and facility expenses on the project selection and evaluation. The results indicate that the two design objectives, to respectively minimize the network‐wide travel time and greenhouse emissions, are conflicting for certain scenarios. Additionally, the results demonstrate the advantages of the network design problem (NDP) considering both multitype recharge service provision and road capacity enhancement over the NDP accounting for the former only.