bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of distributed acoustic sensors based on fiber optic technologies
Authors: Abdykadyrov Askar , Smailov Nurzhigit , Sabibolda Akezhan , Tolen Gulzhaina , Dosbayev Zhandos , Ualiyev Zhomart , Kadyrova Rashida 
Published: November 2024

This research investigates distributed acoustic sensors (DAS) based on fiber optic technologies, focusing on the impact of pressure on signal-to-noise ratio (SNR), noise levels, and dominant frequency shifts. DAS systems are widely used for infrastructure monitoring due to their ability to capture acoustic signals over long distances, making them ideal for seismic and pipeline monitoring.
The study examines how fluctuating pressure affects DAS performance, particularly signal quality and noise reduction. In applications like pipeline leak detection and seismic monitoring, pressure changes can degrade signal clarity and complicate anomaly detection. Understanding this relationship is key to optimizing DAS performance and improving system efficiency.
The experiment varied pressure from 0.1 atm to 5 atm, showing that increased pressure raised SNR from 10 dB to 48 dB, reduced noise from 10 dB to 7 dB, and shifted the dominant frequency from 0.5 Hz to 3 Hz. Fourier analysis provided insights into these frequency spectrum changes. Higher pressure compresses the medium, enhancing signal isolation and improving SNR while reducing noise. The frequency shift results from changes in acoustic wave propagation speed under higher pressure, highlighting its role in signal processing.
The key finding is that higher pressure significantly improves signal quality and reduces noise, enhancing DAS performance. The frequency shift improves environmental detection capabilities. These results are valuable for DAS applications in environments with pressure variations, like pipeline monitoring, where high signal quality is crucial. Improved signal fidelity and frequency shifts make DAS systems more reliable for long-term monitoring and contribute to accurate anomaly detection
PATRIMÔNIO CULTURAL CATÓLICO E AS POTENCIALIDADES PARA USO TURÍSTICO
Authors: Gouveia de Castro Francisco José , Chemin Marcelo 
Published: November 2024

O objetivo deste estudo é analisar as potencialidades para o uso turístico do patrimônio cultural católico na cidade de Curitiba, fundamentada na característica de povoamento étnico da cidade. Diante da discussão teórica a respeito da formação das cidades coloniais como herança de uma característica muito peculiar da civilização que a forma, a pergunta inicial é: é possível a turistificação do patrimônio religioso de Curitiba? Qual a relação histórica entre o patrimônio religioso e a formação da cidade de Curitiba? O resultado do estudo aponta que, a partir da breve análise histórica da cidade, Curitiba herdou a religiosidade, que marcou o processo de assentamento de colonos provenientes da Europa. Considera-se que a questão da imigração teve papel fundamental na formação religiosa do povo curitibano, é possível considerar que Curitiba contém um aparato patrimonial necessário para compor um portfólio de atrativos para a turistificação de cunho cultural e religioso.
TAREFAS DA EPISTEMOLOGIA AXIOLÓGICA PARA AS SOCIEDADES DO CONHECIMENTO E OS ESTUDOS DE RELIGÃO
Authors: Santos Milene Costa dos , Senra Flávio , Corbí Marià , Granés Marta 
Published: November 2024

A epistemologia axiológica é uma disciplina que analisa como se construíram os sistemas de valor para deslindar a condição atual em que se percebe que os sistemas axiológicos coletivos legados não respondem adequadamente à nova situação cultural da contemporaneidade. Sua aplicação destina-se a compreender os valores nas sociedades pré-industriais, nas sociedades industriais e nas sociedades do conhecimento. O trabalho é fruto de pesquisa bibliográfica e procura sintetizar o avanço recente pesquisa sobre a epistemologia axiológica. O presente artigo tem como meta apresentar as tarefas da disciplina epistemologia axiológica face às sociedades do conhecimento, em particular face ao manejo da qualidade humana e da qualidade humana profunda. A partir da gestão das tarefas da epistemologia axiológica compreendemos ser possível lidar com as exigências da sociedade do conhecimento e seus impactos sobre a transição epistemológica e antropológica que afetam os fenômenos religiosos.
ANÁLISE DAS CENAS MEDIÚNICAS E DOS ASPECTOS DO ESPIRITISMO NO ROMANCE A RAINHA DO IGNOTO, DE EMÍLIA FREITAS
Authors: Ribeiro de Sousa Santa Paixão , Câmara Yls Rabelo 
Published: November 2024

Este artigo apresenta um panorama da doutrina espírita, religião codificada por Allan Kardec em 1857, e representada no corpus. Assim, objetivamos realizar uma análise de algumas das cenas mediúnicas que aparecem na obra A Rainha do Ignoto (1899), de Emília Freitas. A beletrista foi responsável por inaugurar a Literatura Fantástica no Brasil com esta obra, que apresenta traços importantes da sociedade da época e do espiritismo. Observam-se também, na obra de Freitas, de temas simples a conceitos complexos dessa doutrina. Muitos aspectos que são considerados fantásticos são explicados por Kardec, que os chamou de “fenômenos mediúnicos”. Nossa pesquisa se justifica por trazer um novo olhar sobre essa obra emblemática por ser feminista, espírita e fantástica, esmiuçando essas questões trazidas pela autora para sua obra-prima e, desse modo, colaborar para que esta escritora seja mais estudada na Academia e mais conhecida pelo público leitor. Para embasar teoricamente este trabalho, nos amparamos nos seguintes estudiosos: Kardec (2008), Amaro (2016), Moura (2017) e Denis (2021), dentre outros. Concluímos que Freitas fez uso deste seu Magnum Opus para veicular uma utopia feminista cujo cerne é espírita.
Fim de semana y Loteamiento clandestino: aproximaciones al universo popular de la vivienda en São Paulo (1970-1990)
Authors: Aravecchia-Botas Nilce , Veiga De Castro Ana Claudia 
Published: November 2024

Este texto parte del análisis de dos películas de la arquitecta y urbanista Ermínia Maricato: Fim de semana (1975) y Loteamento clandestino (1979), e intenta reflexionar sobre algunas relaciones que se establecieron en São Paulo, la mayor metrópolis sudamericana, con la obra de John Turner (a partir de Todo poder al usuario, publicado en 1977), buscando vislumbrar las coincidencias y las discrepancias entre distintos actores que se dedicaron a pensar la vivienda social en América Latina defendiendo la participación popular en su elaboración. Siguiendo la senda abierta por otros investigadores en la Universidad de São Paulo, Maricato elabora una aproximación sociológica y luego etnográfica de las periferias de São Paulo, registrando la forma de construcción de vivienda de la población de bajos recursos y revelando la imposibilidad de aquellos sujetos de acceder al mercado formal de la vivienda. A finales de la década de 1980, en la primera gestión municipal del periodo de la redemocratización, Maricato fue secretaria de Vivienda, y en esta, la ayuda mutua se transformó en política de Estado. Surgió una paradoja: ¿apoyar la autoconstrucción era echar agua al molino de la precariedad o defender ideas libertarias frente a la opresión del Estado autoritario?. Se pretende discutir aquí estas cuestiones, relacionando la producción intelectual brasileña con un movimiento más general, con la intención de contribuir al debate.
Concomitant Arthroscopic Superior Labral and Rotator Cuff Repair
Authors: Rowe Dana G. , Hurley Eoghan T. , Bethell Mikhail A. , Doyle Tom R. , Meyer Alex M. , Lorentz Samuel G. , Klifto Christopher S. , Lau Brian C. , Dickens Jonathan F. 
Published: November 2024

Background:
The aim of this study was to systematically review the literature on concomitant repair of superior labral and rotator cuff tears, in light of the paucity of published clinical evidence.

Methods:
A Preferred Reporting Items for Systematic Reviews and Meta-Analyses compliant search of PubMed, Embase, and Cochrane Library databases was performed for clinical studies of patients undergoing combined repairs of the rotator cuff and superior labrum.

Results:
Ten studies comprising 241 shoulders were included, with a mean age of 52.6 years and mean follow-up of 29.0 months; 67.9% were male patients. Functional outcomes included the mean postoperative American Shoulder and Elbow Surgeons Standardized Shoulder Score of 88.6, University of California at Los Angeles Shoulder Score of 30.6, constant score of 90.4, Simple Shoulder Test score of 8.6, and visual analog scale score of 1.1. Range of motion outcomes demonstrated mean postoperative forward flexion of 159°, external rotation of 68°, and internal rotation of 17°. The overall return-to-play rate was 76.8%, with 67.9% returning to preinjury level. The overall complication rate was 4.1% with an 18.9% rate of rotator cuff retear and 2.4% reoperation rate.

Conclusion:
Arthroscopic concomitant repair of superior labral and rotator cuff tears results in good functional outcomes and range of motion, along with a low reoperation rate. Among athletes, there are moderate rates of return but lower rates of return to the same level of play.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Cautiously optimistic about data-driven algorithms in paediatric critical care, nurses’ perspectives in low-resource settings: a pre-implementation and human-centred design study in Malawi
Authors: Rakers Margot , Mwale Daniel , de Mare Lieke , Chirambo Lezzie , Bierling Bart , Likumbo Alice , Langton Josephine , Team IMPALA Study , Chavannes Niels , Os Hendrikus van , Calis Job , Dellimore Kiran , Villalobos-Quesada María 
Published: November 2024

Abstract

Introduction
Paediatric critical care nurses face challenges in promptly detecting patient deterioration and delivering high-quality care, especially in low-resource settings (LRS). Patient monitors equipped with data-driven algorithms that integrate monitor and clinical data can optimise scarce resources (e.g. trained staff) offering solutions to these challenges. Poor algorithm output design and workflow integration are important factors hindering successful implementation. This study aims to explore nurses' perspectives to inform the development of a data-driven algorithm and user-friendly interface for future integration into a continuous monitoring system for critical care in LRS.
Methods
Human-centred design methods, including contextual inquiry, semi-structured interviews, and co-design sessions, were carried out at the high-dependency units of Queen Elizabeth Central Hospital and Zomba Central Hospital in Malawi. Triangulating these methods, and employing qualitative content analysis principles, we identified what algorithm could assist nurses and used co-creation methods to design a user interface prototype.
Results
Workflow observations demonstrated the effects of personnel shortages and limited monitor equipment availability for vital sign monitoring. Interviews emphasised the advantages of predictive algorithms in anticipating deterioration, underlining the need to integrate the algorithm’s output, the (constant) monitoring data, and the patient's present clinical condition. Nurses preferred a scoring system represented with familiar scales and colour codes. During co-design sessions, trust, usability and context specificity were emphasized as requirements for these algorithms. Four prototype components were examined, with nurses favouring explainable and transparent scores represented by colour codes and visual representations of score changes.
Conclusions
Nurses in LRS perceive that data-driven algorithms, especially for predicting patient deterioration, could improve the provision of critical care. This can be achieved by translating nurses' perspectives into design strategies, as has been carried out in this study. The lessons learned are summarised as actionable pre-implementation recommendations for the development and implementation of data-driven algorithms in LRS.
Health facility revisit and its associated factors among clients utilizing public health facilities in Zanzibar
Authors: Abdul Ramadhani , Bajaria Shraddha , Haji Abdul-Latif , Mselem Mwinyi , Marwa Heri , de Wit Tobias F. Rinke , Risha Peter , Dieteren Charlotte 
Published: November 2024

Abstract

Background
Since 1964, healthcare in Zanzibar has been funded by the government through taxes and is free for all at all points of care. As this system is financially unsustainable, Zanzibar’s healthcare system is undergoing a reform. The current inadequate funding allocation and poor adherence to the referral system lead to an inefficient health system. To gain insights into how precisely inefficient healthcare utilization is concentrated within the Zanzibar healthcare system, we used the capabilities of a relatively new digital healthcare reporting system that uses individual patient-level information. This study determined the magnitude of patient revisits to health facilities and analyzed the factors associated with these revisits.
Methods
This longitudinal prospective study included all clients enrolled in Zanzibar’s digital healthcare utilization system and who had at least one public health facility visit between January 2021 and June 2022. Revisit was defined as revisiting any public health facility within the study period. The time taken to revisit a health facility was calculated as the difference in days between the consecutive multiple visit dates. We applied logistic and lineair regression models to assess the factors associated with revisits to health facilities.
Results
Of the 554,264 enrolled clients, 45,675 (8.2%) visited a health facility during the 18-month study period, of which 28.3% had revisited. Of these, 86.8% revisited the same facility, whereas the rest visited multiple different facilities. Over 10% of the revisit patients had a revisit within ten days. Children under five years of age, females, individuals with higher socio-economic status, those insured, and those diagnosed with non-communicable diseases (NCDs) were more likely to revisit. In addition, patients diagnosed with NCDs, non-residents, children under five years of age, and individuals with a low socioeconomic status were most likely to revisit a health facility within a short time window. Undiagnosed conditions were common at lower-level facilities.
Conclusion
The findings suggest a need to enhance the effectiveness and efficiency of health services delivery, especially at lower levels, to reduce avoidable revisits and consequently reduce the cost per patient. The findings can also be used as a resource to inform ongoing healthcare reform in Zanzibar.
Solubility of ʟ-arginine in twelve mono-solvents: Solvent effects, molecular simulations and model correlations
Authors: Xiao Yusheng , Hu Shen , Zhao Long , Xing Xin , Li Junjie , Ding Min , wang Peng , Li Bingbing 
Published: November 2024

Abstract

The solubility data of ʟ-arginine were measured by the static gravimetric method in twelve mono-solvents (water, methanol, ethyl acetate, ethanol, n-hexane, 2-butanone, isopropanol, 2-butanol, dichloromethane (DCM), dimethylformamide (DMF), 1,4-dioxane and acetonitrile) at T = 283.15-323.15 K and P = 101.2kPa. In the solvents used, solubility increases with increasing temperature. The solubility order of ʟ-arginine at 298.15 K in 12 mono-solvents was ranked as: water > methanol > ethyl acetate > ethanol > n-hexane > 2-butanone > isopropanol > 2-butanol > DCM > DMF > 1,4-dioxane > acetonitrile. According to the results, among the factors affecting the dissolution behavior, Dimroth and Reichardt’s polarity parameters (ET(30)) plays a dominant role, and is also affected by hydrogen bond and cohesive energy density. Molecular modeling including Hirshfeld surface (HS) analysis and molecular electrostatic potential surface (MEPS) were employed to understand internal interactions within ʟ-arginine crystals. The results of interaction region indicator (IRI) and interaction energy show that the solubility of ʟ-arginine in the selected alcohol solvents decreases with the growth of the solvent carbon chain The modified Apelblat model, Yaws model and the Margules model can be well used to correlate the solubility data. Moreover, The Akaike information criterion method was used to evaluate the fitting accuracy of the three models. The evaluation results show that the Yaws model is more suitable for this work. This study enriches the solubility data of ʟ-arginine and provides basic data for the production application of ʟ-arginine.
Deep Generative Optimization of mRNA Codon Sequences for Enhanced Protein Production and Therapeutic Efficacy
Authors: Xie Zhi , Li Yupeng , Wang Fan , Yang Jiaqi , Han Zirong , Chen Linfeng , Jiang Wenbing , Zhou Hao , Li Tong , Tang Zehua , Deng Jianxiang , He Xin , Zha Gaofeng , He Yao 
Published: November 2024

Abstract

Messenger RNA (mRNA) therapeutics show immense promise, but their efficacy is limited by suboptimal protein expression. Here, we present RiboCode, a deep learning framework that generates mRNA codon sequences for enhanced protein production. RiboCode introduces several advances, including direct learning from large-scale ribosome profiling data, context-aware mRNA optimization and generative exploration of a large sequence space. In silico analysis demonstrate RiboCode’s robust predictive accuracy for unseen genes and cellular environments. In vitro experiments show substantial improvements in protein expression, with up to a 72-fold increase, significantly outperforming past methods. In addition, RiboCode achieves cell-type specific expression and demonstrates robust performance across different mRNA formats, including m1Ψ-modified and circular mRNAs, an important feature for mRNA therapeutics. In vivo mouse studies show that optimized influenza hemagglutinin mRNAs induce ten times stronger neutralizing antibody responses against influenza virus compared to the unoptimized sequence. In an optic nerve crush model, optimized nerve growth factor mRNAs achieve equivalent neuroprotection of retinal ganglion cells at one-fifth the dose of the unoptimized sequence. Collectively, RiboCode represents a paradigm shift from rule-based to data-driven, context-sensitive approach for mRNA therapeutic applications, enabling the development of more potent and dose-efficient treatments.
Comprehensive genome-wide identification and expression profiles of SAUR family genes in Fagopyrum tataricum
Authors: Yuan Yi , Qi Huanhuan , Zou Juan , Gui Zihao , Li Yun , Zu Qihang , Gao Yingying , Feng Chenglu , Dong Guoqing , Du Dengxiang 
Published: November 2024

Abstract

Background
Plant development and environmental adaptation are intricately regulated by hormones, with auxins playing a pivotal role in these processes. Within the auxin response family, the Small Auxin Up-regulated RNAs (SAURs) family holds a significant position in controlling plant development and responding to abiotic stress. However, investigations into this family in tartary buckwheat (Fagopyrum tataricum)are still lacking. The whole genome sequence of buckwheat offers a precious opportunity for comprehensive research on the genome-wide expression profile of the SAURs family.
Results
Based on the SAUR domain, 95 FtSAURs genes were identified in buckwheat. Additionally, the structure, evolution, and expression patterns of FtSAURs members were also analyzed. The FtSAURs genes exhibit diverse expression profiles across various developmental tissues and stages, revealing 27 tissue-specific expression genes and 35 hormone-responsive genes. Furthermore, under drought and salt stress conditions, 19 and 13 genes with current changes were detected, respectively. Notably, genes like FtSAUR30 have undergone significant changes after treatment, emerging as potential candidates for stress response.
Conclusions
Our research lays a valuable foundation for further analysis of the abiotic stress resistance mechanism in buckwheat.
WITHDRAWN: Translation of Code-Mixed and Code-Switched Tweets Using LLMs for Enhanced Sentiment Analysis Outcomes
Authors: Sharma Durga , Johari Rahul , Gupta Kalpana 
Published: November 2024

Abstract

The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Assessment of Atherogenic Risk indices and Dyslipidemia in Libyan Smokers
Authors: Alemam Hafsa , Mustafa Ariej , Shebani Afaf , Attayeb Marwa , Akarem Abdurrahman , Elzagheid Adam , Eltaib Farag 
Published: November 2024

Abstract

Background
The atherogenic index of plasma (AIP) is a novel indicator for assessing the risk of atherogenicity and cardiometabolic health. The study was aimed to investigate the correlation between smoking behaviours and atherogenic indices among cigarettes smokers.
Methods
The study was conducted at the Libyan Biotechnology Research Centre in Tripoli, Libya. Two hundred Libyan male subjects were divided into two groups: a group of smokers and a group of non-smokers (as the control group). After an overnight 12-hour fast, five millilitres of fasting whole blood were collected for analysis. Plasma lipid profiles, including total cholesterol (TC), triglycerides (TGs), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were assessed, and levels of atherogenic index of plasma (AIP) were determined.
Results
The results of the study showed that the smokers' group had significantly elevated levels of total cholesterol (TC), triglycerides (TGs), and low-density lipoprotein (LDL) compared to the non-smokers. Interestingly, all smoker participants exhibited AIP levels greater than 0.1, indicating an increased risk of atherogenicity. In contrast, only 15% of the control group had AIP levels indicating intermediate risk, while the remaining 85% had low risk.
Conclusion
Based on these findings, the study concluded that there is a significant association between smoking and atherogenic indexes. It also suggested that AIP may serve as an alternative screening tool in situations where all other atherogenic parameters are normal.
Research on Automatic Generation Method of Spiral Cooling Channel for Injection Mold Based on Spring Model
Authors: Wang Jing , Cheng Fangqi 
Published: November 2024

Abstract

The conformal cooling channel is increasingly favored by mold enterprises for its excellent cooling effect, and more and more designers are using conformal cooling channel in mold design cases. Among numerous cooling channel structures, spiral cooling channel is a very typical and widely used channel structure. Due to its free and flexible spiral shape, designing this channel is not an easy task. For a long time, designers can only rely on basic modeling tools to complete design work through a large number of interactive operations, which often requires a lot of time and effort. Inspired by the spring structure, this paper proposes an automatic generation method for spiral cooling channel. Its basic idea is to first project the spiral line onto the offset surface of the mold surface through the projection curve method, thereby obtaining the initial trajectory line. Then, control points are generated on the initial trajectory line, and finally, spline curves are used to string all control points together to form a scanning trajectory line, and scan along the scanning trajectory line with the specified cross-section to form a cooling channel. Experimental results show that this method is simple and practical, and can quickly generate spiral cooling channels that meet the requirements, greatly saving design time, reducing design errors, and improving design efficiency.