bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping cortical rhythms to infant behavioral tendencies via baseline EEG and parent‐report
Authors: Perone Sammy , Gartstein Maria A. 
Published: May 2019

AbstractAn important goal of developmental science is to understand how the early organization of the brain and behavioral tendencies are interconnected. A foundational step in pursuit of this goal is to identify brain‐behavior relations. Much progress has been made identifying such relations during infancy by linking baseline electroencephalography (EEG) activity to infants’ performance in lab‐based measures of socio‐emotional and cognitive development. Parent‐report represents another resource in expanding our understanding to infants’ behavioral tendencies in their natural environment. The current study explored how parent‐report of 6‐ to 12‐month‐old (N = 53) infants’ attention and regulatory abilities relates to cortical activity. The results confirmed one key hypothesis that lower levels of theta and higher levels of beta and gamma over the frontal region would be related to infants’ attentional abilities. These results are consistent with the extant baseline EEG literature. Cuddliness was robustly related to higher levels of theta and lower levels of beta over the posterior, likely reflecting infants’ tendency to use another person to self‐regulate. Our results indicate links between these cortical rhythms and attention and regulatory processes have infant origins. Our results indicate furture research investigating brain‐behavior relations using parent‐report is warranted.
Simultaneous Determination of Caffeine and Pyridoxine in Energy Drinks using Differential Pulse Voltammetry at Glassy Carbon Electrode Modified with Nafion®
Authors: Farag Amir Shaaban , Pravcová Kateřina , Česlová Lenka , Vytřas Karel , Sýs Milan 
Published: May 2019

AbstractA new voltammetric method for simultaneous determination of caffeine and pyridoxine present in different types of commercial energy drinks has been developed. This electroanalytical method is based on anodic oxidation of these biologically active nitrogen‐containing heterocycles at glassy carbon electrode covered with thin layer of sulfonated fluoropolymer Nafion® using differential pulse voltammetry in 0.1 M Britton‐Robinson buffer of pH 4.5 at potential step 5 mV, potential amplitude 70 mV, and scan rate 50 mV/s. Linear ranges for caffeine and pyridoxine determination were 63.1–600 μM and 7.5–200 μM with the detection limits of 18.9 and 2.2 μM, respectively. It was validated using high‐performance liquid chromatography with spectrophotometric detection. Obtained results have shown that voltammetric approach is very simple and low‐cost analytical method which can be used for routine determination of caffeine and pyridoxine in energy drinks.
Magnetite Nanorods Stabilized by Polyaniline/Reduced Graphene Oxide as a Sensing Platform for Selective and Sensitive Non‐enzymatic Hydrogen Peroxide Detection
Authors: Gabunada Jane Cathleen , Vinothkannan Mohanraj , Kim Dong Hee , Kim Ae Rhan , Yoo Dong Jin 
Published: May 2019

AbstractIn this study, magnetite nanorods stabilized on polyaniline/reduced graphene oxide (Fe3O4@PANI/rGO) was synthesized via a wet‐reflux strategy. The possible formation of Fe3O4@PANI/rGO was morphologically and structurally verified by field emission scanning electron microscopy (FE‐SEM), Fourier transform infrared (FT‐IR) spectroscopy, Raman spectroscopy, X‐ray diffraction (XRD) and X‐ray photoelectron spectroscopy (XPS). Furthermore, the thermal stability of Fe3O4@PANI/rGO was measured by a thermogravimetric analyzer (TGA); the composite had good thermal stability owing to the ceramic nature of Fe3O4. The Fe3O4@PANI/rGO has been applied as a potential sensing platform for electrochemical detection of hydrogen peroxide (H2O2). By the combined efforts of extended active surface area, active carbon support, more catalytic active sites and high electrical conductivity, the Fe3O4@PANI/rGO exhibited an improved performance toward the non‐enzymatic detection of H2O2 in 0.5 M KOH with a fast response time (5 s), high sensitivity (223.7 μA mM−1 cm−2), low limit of detection (4.45 μM) and wide linear range (100 μM–1.5 mM). Furthermore, the fabricated sensor exhibited excellent recovery rates (94.2–104.0 %) during real sample analysis.
Performance Assessment of a Perfluorosulfonic Acid‐type Membrane (i. e. Nafion™ 115) for an Enzymatic Fuel Cell
Authors: Bahar Tahsin , Yazici Mehmet Suha 
Published: May 2019

AbstractA high power enzymatic fuel‐cell was anticipated by using a recently developed glucose oxidase (GOx) immobilized bio‐anode, a conventional platinum−carbon based cathode and a popular high performance 125 μ‐thick perfluorosulfonic acid‐type proton exchange membrane (i. e. Nafion® 115). Unexpected current density decay from 2.13 mA cm−2 to 0.28 mA cm−2 was observed within 2 hours. Polarization measurements and AC impedance analysis indicated that loss of performance was linked to the membrane behavior. Ion exchange between buffer solution and membrane was perceived as the main cause for the fast performance loss. Saturation of the membrane with the cation in the buffer solution diminished proton transfer needed for cathode reaction. Charge transfer resistances, obtained from AC impedance data, increased with time substantially due to cation exchange within membrane. Replacement of membrane with the same enzyme electrode and cathode has resulted 100 % current density recovery on the fuel cell performance. It was concluded that a membrane, not affected by the buffer cations, was required for successful enzymatic fuel cell applications.
Heavy metals inhalation exposure analysis from particulate matter emitted from dry and wet recycling processes of waste electrical and electronic equipment
Authors: Lasithiotakis Michael , Psanis Christodoulos , Triantafyllou Eleni , Nikolaou Panagiota , Kouvarakis George , Michalopoulos Nikolaos , Sinioros Panagiotis , Biskos George 
Published: May 2019

AbstractWaste electrical and electronic equipment (WEEE) recycling processes produce aerosols that influence occupational health. This work is a characterization of aerosols and dust from dry and wet WEEE recycling processes in a small plant. A particle spectrometer measured size distributions of ultrafine particles whereas a deposition impactor collected aerosols for chemical analysis. Powders from milled printed circuit boards and from the cathode ray tube (CRT) processing line were additionally analyzed. Morphological characterization of the dusts by optical and electron microscopy also took place. All plant compartments are subject to aerosol concentrations during the work hours with highest concentration at 105 particles/cm3. The wet recycling technique was more efficient in retaining powders in the solid form than the dry technique. An exposure calculation and a risk assessment of an average worker were carried out. By the worst case scenario the total daily inorganic elements are 80.5 μg, mainly consisting of aluminium copper and iron. The exposure calculation and the risk assessment revealed that accumulation of aerosols in other compartments has a higher impact than the dry process itself. Results showed that for both methods pollutants concentrations were low, even in the worst‐case scenario examined.
Floating solar power plant for sustainable development: A techno‐economic analysis
Authors: Goswami Anik , Sadhu Paromita , Goswami Utpal , Sadhu Pradip Kumar 
Published: May 2019

AbstractThe primary source of energy is depleting day by day owing to an increase in per capita energy consumption. To ensure energy security, to minimize climate change problems and to guarantee sustainable development, the useful utilization of renewable energy potential is of utmost importance. Recent researches reveal significant environmental effects in utilization of photovoltaic technology in large power plants located in urban locations. Further observations depict that the ground mounted PV power plants occupy large land spaces in the modern cities. These have led to the escalation of land price which has resulted in increasing the levelized tariff of electricity. Floating Solar Photovoltaic (FSPV) is an alternative to mitigate the aforesaid problems. In this article, a techno‐economic feasibility of a 10 MW FSPV plant is done to show the economic viability and environmental suitability in maintaining ecological balance through adoption of floating solar photovoltaic technology as compared to conventional ground mounted PV systems. The results show that floating solar photovoltaic power plant has 10.2% more generating capacity than land based PV system and producing 28.38 MU excess generation over the life cycle of the plant. The FSPV plant will save the land cost burden of USD 352125 and water cess burden of USD 47,600. This results in reducing the levelized tariff of FSPV plant to USD 0.026/kWh which is 39% less than land based PV power plant. The FSPV plant will also save 92,945.92 MT of Coal and a total CO2 emission of 340,801.74 ton. The FSPV power plant will help to bridge the gap between energy demand and supply along with reducing the cost of electricity and protecting the environment.
Economic downturns and nurse attachment to federal employment
Authors: Li Danyao , Richards Michael R. , Wing Coady 
Published: May 2019

AbstractThe impact of the financial crisis has been uneven—with differences across industries and occupations. Jobs linked to health care appear better insulated, with nurses specifically showing labor force gains during the recent recession. What is not known is how important public sector employment opportunities are for these national nursing trends. Observing the universe of nurses working for one of the largest (and publicly operated) health care employers, we show that worsening economic conditions lead to stronger job attachment. Relatedly, older nurses also seem more willing to delay retirement and instead transition to part‐time positions during a downturn.
Effective, same‐day preoperative embolization and surgical resection of carotid body tumors
Authors: Katagiri Kartsunori , Shiga Kiyoto , Ikeda Aya , Saito Daisuke , Oikawa Shin‐ichi , Tshuchida Kodai , Miyaguchi Jun , Tamura Akio , Nakasato Tatsuhiko , Ehara Shigeru , Ishida Kazuyuki 
Published: May 2019

AbstractBackgroundThe aim of this study was to evaluate the efficacy of the procedure by analyzing the blood loss and duration of carotid body tumor (CBT) surgery following same‐day preoperative embolization.MethodsWe reviewed the medical records of subjects retrospectively. Fifteen patients with 16 CBTs were enrolled in this study. Our same‐day procedure comprises preoperative embolization of the feeding arteries in the morning followed by surgery within 3 hours after the embolization is completed.ResultsThe mean operative time and the mean amount of blood loss were 138 minutes and 29.3 mL, respectively. The tumor volume after embolization was markedly reduced and the mean reduction rate was 50%. We found that 13 CBTs had more than three feeding arteries. Almost all the postoperative complications, mainly cranial nerve paralyzes, resolved within months after surgery.ConclusionOur same‐day procedure is a safer and superior alternative to traditional CBT surgery, having good outcomes.
Comparing Options for Deriving Chemical Ecotoxicity Hazard Values for the European Union Environmental Footprint, Part II
Authors: Saouter Erwan , Wolff Deidre , Biganzoli Fabrizio , Versteeg Donald 
Published: May 2019

Abstract
Using the European Union's Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) ecotoxicity data, this paper compares 3 different approaches to calculate final substance toxicity hazard values using the USEtox approach (chronic EC50 + acute EC50/2), using only acute EC50 equivalent data (EC50eq), and using only chronic no observed effect concentration equivalent (NOECeq) data. About 4008, 4853, and 5560 substance hazard values could be calculated for the USEtox model, acute only, and chronic only approaches, respectively. The USEtox model provides hazard values similar to the ones based on acute EC50 data only. Although there is a large amount of variability in the ratios, the data support acute EC50eq to chronic NOECeq ratios (calculated as geometric mean) of 10.64, 10.90, and 4.21 for fish, crustaceans, and algae respectively. Comparison of the calculated hazard values with the criteria used by the EU chemical Classification, Labelling, and Packaging regulation (CLP) shows the USEtox model underestimates the number of compounds categorized as very toxic to aquatic life and/or having long-lasting effects. In contrast, use of the chronic NOEC data shows a good agreement with CLP. It is therefore proposed that chronic NOECeq are used to derive substance hazard values to be used in the EU Environmental Footprint. Due to poor data availability for some chemicals, the uncertainty of the final hazard values is expected to be high. Integr Environ Assess Manag 2019;15:796–807. © 2019 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
Time‐of‐flight secondary ion mass spectrometry three‐dimensional imaging of surface modifications in poly(caprolactone) scaffold pores
Authors: Taylor Michael J. , Graham Daniel J. , Gamble Lara J. 
Published: May 2019

AbstractScaffolds composed of synthetic polymers such as poly(caprolactone) (PCL) are widely used for the support and repair of tissues in biomedicine. Pores are common features in scaffolds as they facilitate cell penetration. Various surface modifications can be performed to promote key biological responses to these scaffolds. However, verifying the chemistry of these materials post surface modification is problematic due to the combination of three‐dimensional (3D) topography and surface sensitivity. Time‐of‐flight secondary ion mass spectrometry (ToF‐SIMS) is commonly used to correlate surface chemistry with cell response. In this study, 3D imaging mass spectrometry analysis of surface modified synthetic polymer scaffolds is demonstrated using PCL porous scaffold, a pore filling polymer sample preparation, and 3D imaging ToF‐SIMS. We apply a simple sample preparation procedure, filling the scaffold pores with a poly(vinyl alcohol)/glycerol mixture to remove topographic influence on image quality. This filling method allows the scaffold (PCL) and filler secondary ions to be reconstructed into a 3D chemical image of the pore. Furthermore, we show that surface modifications in the pores of synthetic polymer scaffolds can be mapped in 3D. Imaging of “dry” and “wet” surface modifications is demonstrated as well as a comparison of surface modifications with relatively strong ToF‐SIMS peaks (fluorocarbon films [FC]) and to more biologically relevant surface modification of a protein (bovine serum albumin [BSA]). We demonstrate that surface modifications can be imaged in 3D showing that characteristic secondary ions associated with FC and BSA are associated with C3F8plasma treatment and BSA, respectively within the pore.
18F-NaF PET/CT IMAGING IN FIBROUS DYSPLASIA OF BONE
Authors: Papadakis Georgios Z , Manikis Georgios C , Karantanas Apostolos H , Florenzano Pablo , Bagci Ulas , Marias Kostas , Collins Michael T , Boyce Alison M 
Published: May 2019

ABSTRACT
Fibrous dysplasia (FD) is a mosaic skeletal disorder resulting in fractures, deformity, and functional impairment. Clinical evaluation has been limited by a lack of surrogate endpoints capable of quantitating disease activity. The purpose of this study was to investigate the utility of 18F-NaF PET/CT imaging in quantifying disease activity in patients with FD. Fifteen consecutively evaluated subjects underwent whole-body 18F-NaF PET/CT scans, and FD burden was assessed by quantifying FD-related 18F-NaF activity. 18F-NaF PET/CT parameters obtained included (i) SUVmax (standardized uptake value [SUV] of the FD lesion with the highest uptake); (ii) SUVmean (average SUV of all 18F-NaF–positive FD lesions); (iii) total volume of all 18F-NaF–positive FD lesions (TV); and (iv) total FD lesion activity determined as the product of TV multiplied by SUVmean (TA =  TV ×  SUVmean) (TA). Skeletal outcomes, functional outcomes, and bone turnover markers were correlated with 18F-NaF PET/CT parameters. TV and TA of extracranial FD lesions correlated strongly with skeletal outcomes including fractures and surgeries (p values ≤ 0.003). Subjects with impaired ambulation and scoliosis had significantly higher TV and TA values (P &lt; 0.05), obtained from extracranial and spinal lesions, respectively. Craniofacial surgeries correlated with TV and TA of skull FD lesions (P &lt; 0.001). Bone turnover markers, including alkaline phosphatase, N-telopeptides, and osteocalcin, were strongly correlated with TV and TA (P &lt; 0.05) extracted from FD lesions in the entire skeleton. No associations were identified with SUVmax or SUVmean. Bone pain and age did not correlate with 18F-NaF PET/CT parameters. FD burden evaluated by 18F-NaF-PET/CT facilitates accurate assessment of FD activity, and correlates quantitatively with clinically-relevant skeletal outcomes. © 2019 American Society for Bone and Mineral Research.
A novel strategy of identifying circRNA biomarkers in cardiovascular disease by meta‐analysis
Authors: Li Jia‐Jiang‐Hui , Wang Wei , Wang Xue‐Qing , He Yan , Wang Si‐Si , Yan Yu‐Xiang 
Published: May 2019

AbstractCircular RNAs (circRNAs) are stable and abundantly expressed in vivo but are abnormally expressed in several diseases. This study aimed to identify circRNAs acting as potential biomarkers for cardiovascular disease (CVD). Research were retrieved from the articles published by September 2018 in eight databases to compare circRNA expression profiles between CVD and non‐CVD in human and animal models. Meta‐analysis under a random effects model was conducted. Subgroup analysis of tissue, species, and disease‐specific circRNAs was examined. Sensitivity analysis was performed to explain the uncertainty among all studies. Diagnostic accuracy of circRNAs in CVD was analyzed to testify the discriminative ability. Bioinformatics analysis including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis was conducted. Among 6,284 differentially expressed circRNAs from 32 original studies, only 322 circRNAs were reported in three or more studies. The meta‐analysis identified 63 significantly dysregulated circRNAs, 44 upregulated and 19 downregulated. Among the tissue‐specific or disease‐specific circRNAs identified in the subgroup analysis, two circRNAs (circCDKN2BAS and circMACF1) showed the potential to be circulating biomarkers for CVD. Sensitivity analysis demonstrated 69% of circRNAs were in conformity with the overall analysis. The pooled diagnostic odds ratio was 2.94 (95% confidence interval [CI], 2.35–3.58), and the overall area under the curve value was 0.86 (95% CI, 0.83–0.89). GO and KEGG enrichment analyses indicated that the target genes of circRNAs participate in cardiogenesis‐related processes and pathways. This study demonstrates circRNAs have a high diagnostic value as potential biomarkers for CVD, and two candidate circRNAs, circCDKN2BAS and circMACF1, are potential circulating biomarkers for CVD diagnosis and treatment.
MRI anatomy and pathology of the anal canal
Authors: Erlichman David B. , Kanmaniraja Devaraju , Kobi Mariya , Chernyak Victoria 
Published: May 2019

The normal function of the anal sphincter complex is crucial for quality of life, as it is the mechanism by which fecal continence is maintained. Additionally, the anal sphincter complex is an integral part of the coordinated effort of defecation. As imaging plays an important role in assessment of pathologic conditions involving the anal region, understanding the normal anatomy of the anal sphincter complex is important for correct image interpretation and accurate diagnosis. This review discusses the anatomy and function of the anal sphincter complex, important technical considerations for MRI, and various inflammatory, infectious, and neoplastic processes, as well as pathologic structural conditions that affect the anal region.Level of Evidence: 5Technical Efficacy Stage: 3J. Magn. Reson. Imaging 2019;50:1018–1032.
Galectins‐1 and ‐3 in Human Intervertebral Disc Degeneration: Non‐Uniform Distribution Profiles and Activation of Disease Markers Involving NF‐κB by Galectin‐1
Authors: Elshamly Mahmoud , Kinslechner Katharina , Grohs Josef G. , Weinmann Daniela , Walzer Sonja M. , Windhager Reinhard , Gabius Hans‐Joachim , Toegel Stefan 
Published: May 2019

ABSTRACTDegeneration of the human intervertebral disc (IVD) is assumed to underlie severe clinical symptoms, in particular chronic back pain. Since adhesion/growth‐regulatory galectins are linked to arthritis/osteoarthritis pathogenesis by activating a pro‐degradative/‐inflammatory gene expression signature, we hypothesized a similar functional involvement of galectins in IVD degeneration. Immunohistochemical evidence for the presence of galectins‐1 and ‐3 in IVD is provided comparatively for specimens of spondylochondrosis, spondylolisthesis, and spinal deformity. Immunopositivity was detected in sections of fixed IVD specimens in each cellular compartment with age‐, disease‐, and galectin‐type‐related differences. Of note, presence of both galectins correlated with IVD degeneration, whereas correlation with age was seen only for galectin‐3. In addition, staining profiles for these two galectins showed different distribution patterns in serial sections, an indication for non‐redundant functionalities. In vitro, both galectins bound to IVD cells in a glycan‐dependent manner. However, exclusively galectin‐1 binding triggered a significant induction of functional disease markers (i.e., IL6, CXCL8, and MMP1/3/13) with involvement of the nuclear factor‐kB pathway. This study thus gives direction to further network analyses and functional studies on galectins in IVD degeneration. © 2019 The Authors. Journal of Orthopaedic Research® published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 37:2204–2216, 2019
Restoration of Cellular Proliferation and Characteristics of Human Tenocytes by Vitamin D
Authors: Min Kyunghoon , Lee Ji Min , Kim Mi Jin , Jung Sang Youn , Kim Kyung‐Soo , Lee Soonchul , Choi Yong‐Soo 
Published: May 2019

ABSTRACTVitamin D (Vit D) increases calcium absorption in the intestine after binding to the Vit D receptor (VDR). The VDR has also been identified in muscle cells. Vit D supplementation resulted in improved muscle strength. However, there is a paucity of studies of the role of Vit D on tenocytes. We investigated the effects of Vit D on damaged tenocytes. Human tenocytes were treated with dexamethasone (Dex) to induce cell injury. Expression of the tenocyte‐related markers tenomodulin (Tnmd), tenascin C (Tnc), scleraxis (Scx), mohawk (Mkx), and collagen (Col) 1 and 3 were measured. Then, tenocytes were cotreated with Vit D. 1‐α‐Hydroxylase and VDR were explored in tenocytes. With 10 μM Dex, the growth of tenocytes was significantly inhibited, and the gene expression of Tnmd, Tnc, Scx, Mkx, Col 1 and 3 also decreased. When tenocytes were cotreated with Vit D, cell proliferation recovered in a dose‐dependent manner, and the expression of TNMD and Col 1 improved. When studying the mechanisms of the effects of Vit D on tenocytes, reactive oxygen species produced by Dex decreased with Vit D, and the phosphorylation of extracellular signal–regulated kinase and p38 was stimulated by Vit D cotreatment. 1‐α‐Hydroxylase and VDR were found in tenocytes, indicating that the cells have the ability to use an inactive form of Vit D and interact with it. Vit D is known to perform diverse actions and its protective effects on tenocytes suggest its beneficial role in tendon in addition to muscle and bone. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:2241–2248, 2019