bluuebunny/crossref_metadata_2025_split huggingface dataset:
Isothermal aging effect on SAC interconnects of various Ag contents: Nonlinear simulations
Authors: Gharaibeh Mohammad A. 
Published: November 2024

Abstract
The mechanical behavior of the tin (Sn)–silver (Ag)–copper (Cu) (SAC) lead-free solders is strongly influenced by the isothermal aging due to the evolution of the microstructure and mechanical properties. This study aims to examine the influence of pre-isothermal aging at 100°C on the mechanical behavior of different SACN05 alloys with different silver content including

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and 4% by applying nonlinear finite element analysis. The mechanical properties, including elastic and inelastic properties, of the SAC systems with various Ag percentages are gathered from the literature and incorporated in thorough thermomechanical simulations. In addition to the unaged solders condition, two aging periods, 6 and 12 months, are studied. The computational results showed that the mechanical response of pre-aged SACN05 solders is significantly influenced by the aging duration and silver content. Specifically, interconnects with higher Ag percentage are shown to be more resistive to aging and expected to have lower thermally induced inelastic deformations, strains, and strain energies. Therefore, better thermal fatigue performance and improved failure resistance is potentially expected. However, the pre-isothermally aged SACN05 solders generally exhibit lower resistance to the accumulations of inelastic strains and strain energies. Thus, it is probable that pre-aged SACN05 solders will demonstrate deterioration in thermal fatigue performance compared to unaged interconnects. Nonetheless, the aged SAC solder systems could be an innovative solution for designing electronic devices regularly exposed to shock and impact loading as the aging process significantly reduces the brittleness of the SnAgCu alloys.
Do Good People Love Themselves? On Rational Self-love in Kant
Authors: Tönissen Bas 
Published: November 2024

Abstract
Kant is frequently read as saying that all self-love is bad, and the virtuous agent is one who suppresses self-love as much as possible. This paper argues that this is mistaken and that the right kind of self-love – what Kant calls rational self-love – plays an important role in a successful moral life. It shows how Kant provides a detailed taxonomy of different kinds of self-love. He contrasts the (practical) incentive of self-love with the (pathological) feeling of it, self-love of benevolence with self-love of delight, and self-absorbed/selfish with rational/moral varieties of each. The paper then argues that, while the Critique of Practical Reason only identifies a self-absorbed variety of self-love of delight, self-conceit, it gains a rational counterpart in Religion within the Bounds of Mere Reason: “self-contentment”. This is a positive self-love of delight uniquely felt by the morally good person. It is suggested that this shift reflects Kant’s increasing appreciation of the affective dimension of the virtuous life: for imperfect human beings the moral law must not only be worth obeying, but worth loving. Thus, while for morally bad agents self-love and morality inevitably conflict, good agents can and should love themselves.
How to detonate a semiotic bomb: the dynamics of Lotmanian explosion in the semiosphere
Authors: Rodríguez Higuera Claudio Julio 
Published: November 2024

Abstract
Lotmanian cultural dynamics involve change through textual interaction. Texts, offering vehicles for information, play a central role in this, with cultural change happening in two modes: gradual and explosive instances of texts that alter the semiosphere. This paper focuses on the process of explosion–an unpredictable mode of change in Lotmanian theory–through a metaphorical methodology, by introducing the concept of semiotic bomb. A semiotic bomb works here as a theoretical object that tries to harness the effect of explosion within the semiosphere. The concept of semiotic bomb serves as both a way to examine what is necessary for explosion to happen and as a theoretical exercise in attempting to predict the unpredictable in culture. We contend that cultural change must be understood in terms of sign configurations and information transmission through Charles Morris’s behavioral semiotics, and that this basis works as a complement of Juri Lotman’s cultural dynamics by grounding textual information on behavioral change and resignification. Taking a note from information and semiotic warfare, we look at what it takes for culture to foster change through the prism of Lotman’s theory, and how we could conceptualize intentional change through information manipulation and presentation. The paper offers a novel look into the logic of explosion within the semiotic theory of Juri Lotman and proposes conceptual avenues for exploring, analyzing and tentatively implementing the concept of explosion by the proposed idea of a semiotic bomb.
Adequacy of Copyright Information or Documentation, the Need for Training in, and Evaluation of Mechanisms for Delivering Copyright Education in Academic Libraries in Ghana
Authors: Adu Theresa L. , Asare Comfort Boatemaa , Arthur Charles Kofi 
Published: November 2024

Abstract
With academic libraries becoming increasingly involved in copyright issues, the ability to responsibly identify a copyright-protected material is becoming important in the administration of reprographic materials in academic libraries. A mixed methods approach was employed to evaluate the adequacy of copyright information or documentation, the need for training, and the mechanisms for educating library users on responsible use of reprographic materials that ensures a balance of stakeholder rights. Quantitative data was collected from 38 library staff and 530 postgraduate students, while qualitative data was collected from four head librarians (through one-on-one interview sessions), and two groups of six postgraduate students each from two public and two private universities in Ghana (through focus group discussion sessions). Only 21.4 % stated that copyright information or documentation on copyright policies on their university campuses was adequate. Copyright education for both staff and students was generally low in all the four institutions. Only “classroom training” had significant impact on users’ understanding of copyright laws and policies. “Professional associations,” “study visits,” and “consultant training” had little impact on the understanding of students about copyright laws despite most library staff being either “comfortable” or “very comfortable” with their level of knowledge on copyright issues. There is therefore the need to incorporate copyright issues in the school curriculum for students as well as institute CPD programs for professional librarians if academic librarians are to efficiently and adequately play their roles as agents of copyright education to the university community.
Ferroptosis-related prognostic model of mantle cell lymphoma
Authors: Gao Qianwen , Wang Xin , Zhang Yue , Wen Jingjing , Wang Fangfang , Lin Zhimei , Feng Yu , Huang Jingcao , Li Qian , Luo Hongmei , Liu Xiang , Zhai Xinyu , Li Linfeng , He Siyao , Mi Ziyue , Zhang Li , Niu Ting , Xu Caigang , Zheng Yuhuan 
Published: November 2024

Abstract

Background
Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin’s lymphoma. Ferroptosis, an iron-dependent programmed cell death, is closely related to cancer prognosis. In this study, we established a model of ferroptosis related genes for prognostic evaluation of patients with MCL.

Methods
Using the single-cell RNA sequencing datasets GSE184031 and mRNA sequencing data GSE32018 from the Gene Expression Omnibus, we identified 139 ferroptosis-related genes in MCL. Next a prognostic model was constructed by Cox regression and Least absolute selection and shrinkage Operator regression analysis. Finally, we used CIBERSORT to analyze the immune microenvironment and the “oncoPredict” package to predict potential drugs.

Results
In our model, the prognosis of MCL patients was assessed by risk scoring using 7 genes ANXA1, IL1B, YBX1, CCND1, MS4A1, MFHAS1, and RILPL2. The patients were divided into high-risk and low-risk groups based on our model, and the high-risk patients had inferior overall survival. Finally, according to our model and computational drug sensitivity analysis, four small molecule compounds, BMS-754807, SB216763, Doramapimod, and Trametinib, were identified as potential therapeutic agents for patients with MCL.

Conclusion
In summary, we provide a prognostic model with ferroptosis-related gene signature for MCL. This study provides a prognostic model with ferroptosis-related gene signature for MCL. The results show that the model helps predict prognosis in MCL.
Shorter but richer versus longer with less information: linguistic differentiation between British Sign Language and sign supported English
Authors: Rowley Katherine , Cormier Kearsy 
Published: November 2024

Abstract
The distinction between natural sign languages and sign-supported speech is a controversial topic and difficult to assess purely on structural terms because of language contact. Here, we consider British Sign Language (BSL) and Sign Supported English (SSE) with reference to Irvine and Gal’s (2000. Language ideology and linguistic differentiation. In P. V. Kroskrity (ed.), Regimes of language, 35–84. Oxford: Currey) framework on linguistic differentiation. Using interview data from 121 deaf BSL signers from the BSL Corpus, we show that this framework allows us to better understand how BSL and SSE are defined by BSL signers. We refer to the semiotic processes of this framework: iconisation, fractal recursivity, and erasure. BSL, including its varieties, is strongly associated with deaf communities in Britain. Specific grammatical forms in BSL that differ markedly from English constructions are presented as exemplars of sign language use (iconisation), oppositions between deafness and hearingness are repeatedly applied to different social groups (fractal recursivity and iconisation), and occurrences that may not align with this opposition are rarely acknowledged (erasure). We suggest that these semiotic processes are motivated by language maintenance and educational policies. We conclude with a discussion on how deaf signers distinguish between BSL and SSE, suggesting distinctions made are ideologically driven with political and historical roots and better understood from a translanguaging perspective.
Abstract and keywords in British Sign Language (BSL) can be found here: https://www.youtube.com/watch?v=ZtZomy9ab2U.
Evolution of climate-smart agriculture research: A science mapping exploration and network analysis
Authors: Zaidi Abdelhamid , Ajibade Samuel-Soma M. , Shah Mohd Asif , Bashir Faizah Mohammed , Falude Emmanuel , Dodo Yakubu Aminu , Adewolu Adeoye Olugbenga , Ngo-Hoang Dai-Long 
Published: November 2024

Abstract
The integrated approach of bibliometric mapping and literature review was adopted to critically examine the evolution of climate-smart agriculture (CSA) research climate from 2012 to 2023 using publications data recovered from the Elsevier Scopus database. The publication trends, stakeholder profiles, social networks, and thematic area analysis on CSA research were examined. Findings revealed that the publication trends on CSA research revealed an incremental pattern from 2012 to 2023. Stakeholder profile analysis identified numerous authors, affiliations, and countries actively engaged in CSA research. The most prolific researcher is Mangi L. Jat, whereas Wageningen University & Research is the most prolific affiliation. Finally, the United States is the most prolific nation. Stakeholder’s productivity was ascribed to a combination of factors ranging from access to research funding to collaborations. The most active funder of CSA research is CGIAR (Consortium of International Agricultural Research Centres), which has funded 52 publications, gained 1,529 citations, and an h-index of 20. The CGIAR has greatly supported the works of highly prolific authors such as Mangi L. Jat, Hanuman S. Jat, and Suresh K. Kakraliya. Social network analysis revealed strong, active, and extensive links, particularly between nations such as the US, India, Kenya, and Ethiopia. The cluster and thematic area analyses of the CSA research landscape revealed three areas, namely, Climate-Resilient Agricultural Adoption, Climate-Responsive Agricultural Practices, and Integrated Food Systems, which are the current focus of stakeholders in the field. Overall, the study showed that CSA is a broad and interdisciplinary topic with a significant impact on the social, economic, and environmental aspects of humanity and societies across the globe.
Implementation and evaluation of Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) for the treatment of patients with malignant pleural effusion: study protocol for the Danish phase-I PITAC-OPC5 study
Authors: Hansen Pernille Schjødt , Graversen Martin , Detlefsen Sönke , Ainsworth Alan Patrick , Fristrup Claus Wilki , Eckhoff Lise , Jelin-Klaric Mia , Mortensen Michael Bau 
Published: November 2024

Abstract

Objectives
Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) is a minimally invasive cancer-directed therapy for patients with malignant pleural effusion (MPE) and/or pleural metastasis (PLM). PITAC is based on Pressurized IntraPeritoneal Aerosol Chemotherapy, which has proven to be safe and feasible. Since 2012, 47 PITACs have been published, and prospective data on feasibility, safety and potential local response are lacking.

Methods
The prospective, controlled, phase-I study is designed to treat MPE with PITAC. There are no data to support the estimated number of patients needed, but previous experience estimates the non-access rate to 20 %. Twenty eligible patients with MPE will receive two or more PITACs at four-week intervals. During video-assisted thoracoscopy, MPE and/or pleural lavage fluid is evacuated, and the extent of visible PLM is assessed. Pleural biopsies are collected, if possible, for histological response as per Thoracic Regression Grading Score (TRGS). Patients are screened for treatment-related intra- and postoperative complications. The primary outcome is the number of patients with Clavien-Dindo ≥3b or Common Terminology Criteria for Adverse Events≥4 within 30 days. Secondary objectives include PLM-score, TRGS and cytology, length of hospitalization, personnel safety, quality of life, and change in MPE volume.

Results
PITAC is expected to be safe and feasible for patients and personnel, and achieve positive results in the reduction of MPE volume.

Conclusions
The results may significantly impact the next clinical, technical, and scientific steps in the implementation of PITAC. Given the suboptimal treatment options for MPE and the seemingly promising results of PITAC, we find the implementation of PITAC ethically reasonable and sound.
Hierarchical macro/mesoporous γ-Al2O3 as column matrix for development of low specific activity 99Mo/99mTc generator via 100Mo (γ, n)99Mo reaction
Authors: Gao Ruiqin , Wang Jieru , Tian Wei , Huang Qinggang , Lin Mu , Wu Xiaolei , Qin Zhi 
Published: November 2024

Abstract

99mTc, the daughter product of 99Mo, is a γ-emitting radionuclide with essential diagnostic applications in nuclear medicine. In this paper, an accelerator-based method (100Mo (γ, n)99Mo) for production of 99Mo and 99mTc has been explored. Approximately 68.3 MBq of 99Mo was successfully produced by the irradiation of 100Mo metallic target for 40 h using electron beam with energy of 50 MeV and current of 0.2 μA at electron linear accelerator (Institute of Modern Physics, Chinese Academy of Sciences, IMPCAS). Different types of 99Mo/99mTc generators were prepared using hierarchical macro/mesoporous γ-Al2O3 (HMMA) as column adsorbent, and their performances were evaluated for over one week. 99Mo/99mTc generator with a column (3 mL, 4.2 × 0.95 cm) packed with 0.6 g HMMA exhibited excellent eluting performance. 99mTc could be collected within 4.0 mL of saline solution with high purity, and the elution efficiency could reach >85 %. Furthermore, 99Mo breakthrough in the eluates was negligible (<2 × 10−3 %) and concentration of impurity (<10 ppm) was acceptable. Finally, the enriched 100Mo was eluted from the spent 99Mo/99mTc generator using 1.0 mol/L ammonium hydroxide, and then reduced by high-temperature hydrogen reduction process with a total recovery of 95.3 %. This work demonstrated that the preparation of 99Mo via 100Mo (γ, n)99Mo reaction and isolating 99mTc using HMMA column chromatography have a potential in application.
Comprehensive and in-depth insights into photo-assisted halogenation reactions: a pharmaceutical industry perspective
Authors: Prabhu Aditi , Mali Pradip , Singh Satyapaul A. , Sreedhar Inkollu 
Published: November 2024

Abstract
Halogenation reactions are a vital area of study for the pharmaceutical industry. The study of the reaction conditions along with the reactors and their scale-up is a thrust area in drug synthesis and manufacturing. There is a shift in the research community towards accommodating renewable energy sources which has driven scientists to include energy sources that are sustainable and aid in making the overall process efficient. This review provides a comprehensive overview of the challenges in selecting the best catalyst, light source and reaction conditions for the fluorination, chlorination and bromination reactions. This paper goes a step further to explain the photoreactors’ design and modelling as well as the scale-up of the same. Overall, it provides a comprehensive view of diverse scientific areas, from halogenation in drug synthesis to the potential of photochemical batch and flow approaches in halogenation reactions.
A structured review of the associations between breast cancer and exposures to selected organic solvents
Authors: Westra Sydney , Goldberg Mark S. , Labrèche France , Baumgartner Jill , Ho Vikki 
Published: November 2024

Abstract

Introduction
Our objective was to identify published, peer-reviewed, epidemiological studies that estimated associations between the risk of developing or dying from malignant breast cancer and past exposure to selected organic solvents with reactive metabolites, to delineate the methods used and to synthesize the results.

Content
We undertook a structured review of case-control and cohort studies used to investigate breast cancer risk and exposure to selected organic solvents that produce reactive metabolites in the body. We used SCOPUS, MEDLINE (Ovid) and Web of Science databases from 1966 to December 31, 2023 to identify epidemiological studies that estimated associations between the risk of developing or dying from malignant breast cancer and past exposure to selected organic solvents with reactive metabolites and organic solvents combined as a group.

Summary
We described essential methodological characteristics of the 35 studies and presented quantitative results by individual solvent and other characteristics. We did not find compelling evidence that any of the selected organic solvents are implicated in the etiology of breast cancer.

Outlook
As millions of workers are exposed to organic solvents, this topic necessitates further investigation. Future research should focus on elucidating organic solvents that may contribute to the burden of breast cancer.
Beyond “Made in China”: visual rhetoric and cultural functionality in translating the traditional Chinese totem Loong 龙
Authors: Li Ke , Xu Zihan 
Published: November 2024

Abstract
Current inter-disciplinarity has rendered it feasible to utilize implements and methodologies to navigate around the communication of fashion at textual as well as material levels, reified by inter-semiotic and cultural translation. Fashion communication, from the perspective of post-translation studies, is a process of cultural translation with visual symbols as its text, visual rhetoric as its core meaning system, and visual stylists as its translator. This study takes one of the most formidable and awe-inspiring icons – the Chinese totem Loong 龙 as the main research object, through the analysis of multifarious styles of visual text structures across the entire process of fashion communication, to deconstruct the semiotic transformation of Loong 龙 by means of visual rhetoric. In forging this rhetorical dynamic within the realm of visual art, the cultural translative procedure is orchestrated primarily through the registers of field, tenor, and mode. Furthermore, it is molded by the intricate interplay of transitivity, mood, and modality, culminating in this newly proposed concept – “cultural functionality” through the lens of systemic functional grammar. This study, by means of this rhetorical, semiotic approach, forays into the profundity of what is named as “Made in China” and showcases Chinese spirit in fashion communication.
Ektacytometric examination of red blood cells’ morphodynamical features in diabetic nephropathy patients
Authors: Sari-Ak Duygu , Helvaci Nazli , Kural Alev , Tanrikulu Seher , Can Ozgur , Caglar Sena Ebru , Caglar Hifa Gulru , Baydili Kursat Nuri , Karakoc Yunus 
Published: November 2024

Abstract

Objectives
Diabetic nephropathy (DN), the primary cause of end-stage renal disease, is associated with chronic hyperglycemia and elevated blood pressure. This study investigates the correlation between DN and changes in hemorheology, which involves blood flow properties.

Methods
At the University of Health Sciences in Istanbul, Türkiye, erythrocyte deformability, aggregation, and viscosity were measured using advanced ektacytometry (Lorrca® Maxsis) on blood samples from 31 healthy individuals, 41 diabetic patients, and 45 patients with diabetic nephropathy from University of Health Sciences Haydarpasa Numune Training and Research Hospital. All hematocrit values were standardized to 40 %.

Results
Deformability of red blood cells (RBCs), indicated by the elongation index at shear stresses from 0 to 30 Pa, significantly decreased in the diabetic nephropathy group compared to diabetic patients without nephropathy and healthy controls (mean min-max SD: 0.650 (0.63–0.67) vs. 0.659 (0.64–0.68) and 0.642 (0.62–0.66), respectively; p<0.01). RBC aggregation significantly increased in the diabetic nephropathy group (mean min-max SD: 77.52 (57.84–90.7) vs. 69.96 (53.13–80.53) in controls; p<0.01), and plasma viscosity was also higher (mean min-max SD: 1.48 (1.27–2.02) mPa·s vs. 1.34 (1.22–1.72) mPa·s in controls; p<0.001).

Conclusions
Our findings demonstrate marked hemorheological changes in diabetic nephropathy patients. These changes suggest that evaluating RBC deformability, aggregation, and viscosity is critical for developing therapeutic strategies aimed at reducing vascular complications and preventing tissue damage in diabetics.
Customized Employment: A Way Beyond “Food, Flowers and Filth”?
Authors: Assaf Marie 
Published: November 2024

Abstract
This article critically examines the effectiveness and limitations of contemporary employment programmes in the U.S. designed for individuals with disabilities, particularly those with intellectual and developmental disabilities (IDD). Despite the noble intentions and efforts to promote inclusion, the prevailing logic of employment often confines these individuals to peripheral, unskilled job markets. The analysis highlights a systemic issue within the welfare state framework, where customized employment initiatives, while personalized, fail to lift individuals out of precarious situations. By delving into the perspectives of agents from nonprofits involved in these programmes, the article underscores the role played by such initiatives in categorizing individuals based on definitions of employability.