bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Intermittent and Intradermal Suture in Total Knee Arthroplasty
Authors: Huang Changzhi , Zhang Shimin , Wang Xiaoyong , Xu Nanyi , Lin Jiuzao 
Published: November 2024

Abstract

Intermittent suturing and intradermal suturing are commonly used in total knee arthroplasty. The use of an intradermal suture has gained popularity because of its aesthetic incision and small scar characteristics. Therefore, we performed a retrospective study to evaluate the differences between these two treatments.We retrospectively analyzed patients who underwent primary TKA for knee osteoarthritis from 2020–2022 from a department database. Patients were categorized into the traditional and modified groups basis of the different methods used to suture the skin.The clinical indicators were observed and compared. Compared with those of the traditional group, the incision suture time, number of suture reactions, postoperative hospitalization time, PSAS, and OSAS of the modified group were lower. The VAS scores of the modified group were lower than those of the traditional group at 3, 5, and 7 days postoperative; the HWES scores at 1, 2, 6, 12, and 24 weeks postoperative; and the satisfaction scores of the incision aesthetics were significantly greater than those of the traditional group(P < 0.05). The number of incision dressing changes, the number of poor incision alignment cases, the number of incision exudation cases, and the number of non-grade A healing cases in the modified group were slightly lower than those in the traditional group, with no statistical significance (P > 0.05). The flexion angle, extension angle, and flexion-extension angle of the knee joints in the two groups at 6, 12, and 24 weeks postoperative were significantly greater than those at baseline (P < 0.05), but the differences were not statistically significant(P > 0.05). Compared with the traditional suture method, the modified intradermal suture method can shorten the incision suture time and postoperative hospitalization time of TKA patients, reduce suture reactions, alleviate postoperative incision pain, improve the degree of incision scarring and increase patient satisfaction with incision aesthetics.
Paracentral Acute Middle Maculopathy as a Major Clinical Manifestation of Adenosine Deaminase-2 Deficiency
Authors: Ariello Leonardo Eleuterio , Andrade Thais Souza , Fernandes Rodrigo D. , Cunha Leonardo P. , Monteiro Mário L. R. 
Published: November 2024

Abstract

BACKGROUND Adenosine deaminase-2 (ADA2) deficiency is a rare autosomal recessive autoinflammatory syndrome, typically presenting in young patients with a broad spectrum of phenotypes. These phenotypes may include primary immune deficiencies, livedo reticularis, and various hematological abnormalities. Visual loss associated with ADA2 deficiency is uncommon and, when it does occur, is often linked to major vascular involvement, such as occlusion of the ophthalmic arteries.CASE PRESENTATION: A 31-year-old woman with a presumptive diagnosis of common variable immunodeficiency and livedo reticularis presented with sudden onset severe visual loss in the left eye due to paracentral acute middle maculopathy (PAMM) followed a few weeks later by a lacunar stroke. An extensive laboratory investigation including genetic testing led to the diagnosis of ADA2 deficiency, a rare autoinflammatory syndrome. Treatment regimen was switched to anti-TNF-α inhibitors, leading to disease remission with no further vascular events over a two-year follow-up period.CONCLUSION This case serves to emphasize the importance of considering ADA2 deficiency in patients with PAMM, particularly when it occurs in young patients with a history of strokes and/or immunological abnormalities.
Native Australian seedlings exhibit novel strategies to acclimate to repeated heatwave events
Authors: Alvarez Philippa , Harris Rosalie J , Cook Alicia M , Briceño Verónica F , Nicotra Adrienne B , Leigh Andrea 
Published: November 2024

Abstract

1. Heatwaves are becoming more intense and frequent. Plant photosystem thermal thresholds can vary with species, but also shift in response to environmental triggers. Both upper and lower thresholds can acclimate to repeated heatwaves through ecological stress memory, where prior exposure primes them for subsequent events. The extent to which acclimation to repeated heat stress events varies among environmental origin and/or species is unknown. Different acclimation strategies might reflect biome of origin, or may be species-specific. 2. For 12 species from two contrasting biomes – extreme desert and benign coastal temperate – we investigated responses to two simulated heatwaves, via shifts in upper and lower critical temperatures of photosystem II, and the difference between these thresholds, thermal tolerance breadth (TTB). 3. Biome of origin had no effect on thermal tolerance. Observed differences among species following heat events suggested two possible acclimatory strategies. In some cases, species increased thermal thresholds during the first heatwave, but at the cost of reduced thermal tolerance during the second heatwave, a sprinter strategy. Other species acclimated to the first heatwave and further increased thermal tolerance to a second heatwave, indicative of ecological stress memory, a marathoner strategy. 4. Synthesis: These among-species responses to heatwaves could suggest distinct vulnerabilities and resilience to repeat heat stress events, with some species having limited capacity to tolerate consecutive heatwaves, possibly as the cost of acclimation is too great, with other species having the advantage of increased tolerance via stress memory, helping them survive future stress, at least in the short-term.
Irreversible transesterification reactions in aqueous media
Authors: Hollmann Frank , Wu Bin , Ma Yunjian , Feng Chenhao , Domestici Chiara , Wang Yutong , Hilberath Thomas , Hanefeld Ulf , Pidko Evgeny , Wang Yonghua 
Published: November 2024

Abstract

Transesterification reactions are fundamental transformations in organic chemistry. However, performing these reactions in aqueous media is challenging due to the competing hydrolysis reaction. Kinetic control and the use of activated acyl donors offer potential solutions, but they are difficult to implement. In this study, we present a mutant of alcohol oxidase from Phanerochaete chrysosporium (PcAOx-VPN) that exhibits no hydrolytic activity. Its hydrophobic active site efficiently excludes water, enabling irreversible transesterification reactions in water—previously considered impossible—thereby opening novel opportunities for chemical synthesis. Remarkably, PcAOx-VPN, as a flavin-containing enzyme, catalyzes transesterification, a promiscuous activity not previously known in this enzyme class, expanding the functional repertoire of these versatile enzymes.
Design and development of Ms Radiance: a culturally sensitive, tailor made bilingual educational initiative utilizing Instagram® for transgender women in Malaysia
Authors: Telang Lahari , Daud Hezreen Shaik , Hanif Zariq Rosita , Nizam Betty , Cotter Aoife G. , Rashid Abdul 
Published: November 2024

Abstract

Background: Transgender women in Malaysia are marginalized and face barriers in accessing health care. Low oral health care utilization along with gaps in knowledge and perceived low risk of transmission of STIs through oral sexual practices have been identified through formative research. Tailored educational interventions focusing on the needs of transgender women in Malaysia are crucial for addressing these gaps.
Methods: Employment of the ADDIE (analyse, design, develop, implement and evaluate) instructional framework and participant involvement and engagement (PPIE) of the transgender community in the design and development of a social media based educational intervention, Ms Radiance is described. Pilot implementation of the intervention on Instagram® for a 3-week period was evaluated with an online pre-test/post-test study of a single group of transgender women (n=30) participants along with assessment of feasibility and accessibility.
Results: Areas of concern identified through formative research were used to derive research objectives of the intervention and mapped to the educational content. PPIE was vital in ensuring that the educational content was delivered as artistic posts, stories and reels that were bilingual, peer-reviewed and culturally competent. Ms Radiance was feasible (100% retention, 93% post-intervention completion rate) and acceptable (positive post-intervention feedback and 79% indicated recommending the intervention to others).
Conclusion. A first of its kind intervention for transgender women in Malaysia was designed and developed with PPIE and pilot tested. The feedback from the pilot will help in improving the intervention for a scaled-up version of the study.
Outstanding formaldehyde abatement performance and preferable resistance to SO 2 and H 2 O over CrO x -CeO x facilitated hierarchical porous biochars catalysts
Authors: Jiang Yun , Feng Xiaoxin , Gao Lei , Dai Jiangyong , Xie Dong , Li Caiting , Peng Weizhi , Huang Zhixiu , Xiong Huiyu , Quan Yukai , Sun Cheng 
Published: November 2024

Abstract

A suite of CrCe oxides facilitated hierarchical porous biochars from walnut husks and rice straws (XCryCe1-y/WSAC) were readily synthesized for formaldehyde (HCHO) abatement. BET, XRD, XPS, SEM, H2-TPR, TG-DTG, and in situ DRIFTS were adopted to disclose their physicochemical properties and the elimination mechanism of HCHO. 18%Cr0.5Ce0.5/WSAC exhibited splendid HCHO abatement efficiency (99.2%) at 280°C. The effects of O2, SO2, H2O for HCHO abatement over 18%Cr0.5Ce0.5/WSAC were trialed, and the strangulation influences of SO2 counteracted the furtherance effect of O2 to some extent, which was relieved by the facilitation of H2O. CrOx-CeOx co-facilitated WSAC presented better performance than Cr or Ce oxide separately facilitated WSACs, which was associated with the redox cycle of Cr6++Ce3+↔Cr3++Ce4+, resulting in higher redox capability, better dispersion of active ingredient, more oxygen vacancies and superior active oxygen mobility. Furthermore, the hierarchical porous support accelerated the diffusion and mass transfer of reactants and intermediates. Noteworthily, the effects of CrOx-CeOx and the hierarchical porous structure of the support on the tolerance to SO2 and H2O were deeply and systematically investigated. Ultimately, 18%Cr0.5Ce0.5/WSAC emerged desirable prospects in practical applications thanks to splendid catalytic performance and satisfactory resistance to SO2 and H2O.
The effect of bone mineral density on femoral stem subsidence in primary cementless total hip arthroplasty: A prospective study
Authors: Kalyenci Ahmet Sinan , Doğan Ibrahim , Tekin Saltuk Bugra , Ozmen Zana , Senel Ahmet , Ozturkmen Yusuf 
Published: November 2024

Abstract

Background: The success of primary total hip arthroplasty (THA) in patiens with primary osteoarthritis (OA) of hip is significantly inflenced by stem osteointegration, migration and placement. Additionally, the bone mineral density (BMD) of the proximal femur and the femoral morphology play important roles in these outcomes. We aimed to prospectively evaluate the effect of BMD on subsidence who underwent primary cementless THA for primary OA of hip.
Methods: We conducted a prospective observational study on 70 hip (65 patients) diagnosed with primary OA of hip who underwent primary cementless THA. Patients were grouped according to preoperative BMD and proximal femur anatomy based on Dorr classificaiton. Harris hip score (HHS) and radiological subsidence values ​​were used for postoperative clinical evaluation.
Results: The mean follow-up was 24.6 ± 5.8 months. Of the 70 hips, 22 (31.43%) were Dorr type A, 44 (62.86%) type B, and 4 (5.71%) type C. According to total femur T scores, 43 patients (61.43%) had normal BMD, while 27 patients (38.57%) were identified as osteopenic or osteoporotic. The mean axial migration at last follow-up was 1.04 ± 0.69 mm. No significant influence on migration was found regarding total femur T score levels and femoral morphologies.
Conclusions: In our study, we investigated the early results of cementless THA in patients with low BMD and advanced age group. We evaluated the clinical and radiological results in groups with different bone density and femoral morphology. In our results, evaluated in light of similar studies, we found that HHS, subsidence values and Engh scores were comparable between patients with normal and low BMD, with no statistically significant differences observed.
Material Classification System using Inductive Tactile Sensors and Machine Learning Algorithms
Authors: Jiang Yuning 
Published: November 2024

Abstract

This study presents an innovative material classification system designed using an inductive tactile sensor and machine learning algorithms. A simple-structured sensor based on the principle of electromagnetic induction was developed to capture varying inductance signals induced by different materials with distinct magnetic properties, facilitating material detection and distinction. A dataset comprising 10 types of materials was evaluated with the sensor, and three machine learning algorithms, namely the support vector machine, k-nearest neighbors, and naïve bayes models, were trained using the output data. Subsequent performance evaluation employed several metrics, including mean accuracy, precision, recall, and others, and revealed that the naïve bayes model exhibited superior performance in prediction. Finally, an enhanced aggregated classification model was developed, where the soft voting ensemble learning technique was employed with the individual classifiers mentioned above as base models. The study underscores the system’s feasibility for potential implementation in high-performance manufacturing and intelligent automation, such as the motorsports and automotive sector, which could facilitate the development of an Industry 4.0 environment. Furthermore, the study also suggests routes for future work that could bolster performance of this system and emphasizes on the necessity for practical implementations to link the system with real-world applications.
Reducing game form recognition error in Becker DeGroot Marshak One-Shot Experiments
Authors: Bou-Ysàs Sílvia , Montañola-Sales Cristina , Teixidó-Navarro Francesc , Duran-Pinochet Ignacio 
Published: November 2024

Abstract

This study investigates strategies to enhance game form recognition within economic experiments, particularly focusing on the Becker DeGroot Marshak (BDM) method. The BDM method aims to elicit individuals’ subjective valuations of objects, yet challenges arise in participants’ comprehension and optimal decision-making. Drawing on cognitive load theory, this research proposes integrating output tables to facilitate participants’ understanding and decision-making in BDM experiments. A randomized controlled experiment was conducted with 129 participants from diverse academic backgrounds. Results reveal that participants exposed to output tables exhibited improved game form recognition and higher rates of optimal bidding. Gender and specialization analyses provided further insights into participant performance. These findings contribute to refining economic experimental methodologies and understanding cognitive influences on decision-making, aligning with principles of modality and divided attention in organizational behavior research.
Intercomparison of Ocean Reanalyses for Interannual Ocean Temperature Variability in the Tropical Atlantic
Authors: Prigent Arthur , Richter Ingo , Storto Andrea , Farneti Riccardo , Koungue Rodrigue Anicet Imbol , Okumura Yuko , Chang Ping 
Published: November 2024

Abstract

Ocean reanalysis (ORA) products are widely used by the scientific community and are essential tools for monitoring and understanding tropical Atlantic inter-annual variability. However, large differences have been observed among these products in the tropical Atlantic Ocean. In that context, an ensemble of seven ORAs is examined and compared over the period ranging from January 1993 to December 2017. The analysis reveals a considerable spread (> 0.3º C) in tropical Atlantic Ocean temperature anomalies in the upper 150 m. Along the equatorial Atlantic and southwest African coast, which are regions of high interannual variability, most of the discrepancies among the ORAs are located around the depth of the thermocline. This spread is linked to the amount of in situ profiles assimilated by ORAs. The deployment of the PIRATA mooring array in early 1998 improved ORA consistency along the equatorial Atlantic, as well as down the path of equatorial Kelvin waves and subsequent coastal trapped waves. Despite a decreasing trend of -0.04º C·decade−1 of the ensemble spread averaged over the upper 150 m of the tropical Atlantic ocean, a few regions with limited in-situ observations present smaller improvements, such as in the Benguela upwelling system and around 15º W, 10º S. A comparison between ORAs and forced-ocean models indicates that ocean model biases contribute little to the total ensemble spread. Instead, it suggests that most of the spread can be attributed to discrepancies among the atmospheric fields used to force ORAs. The ensemble spread of the equatorial Atlantic zonal wind anomalies across four atmospheric reanalyses suggests that their consistency has not improved or even worsened.
Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single-center, open-labeled study (AEGIS trial, neoadjuvant immunochemotherapy)
Authors: Li Yingyi , Cao Yuqin , Wang Xipeng , Li Chengqiang , Zhao Liqin , Li Hecheng 
Published: November 2024

Abstract

Background: For resectable adenocarcinoma of the esophagogastric junction (AEG), current treatment exploration primarily focuses on perioperative PD-1/PD-L1 plus chemotherapy regimens, but their long-term survival benefits still need further investigation. Adebrelimab, as a novel PD-L1 antibody, has not yet been proven for its efficacy and safety in adenocarcinoma of the esophagogastric junction.
Methods: The AEGIS study is a prospective, open-labeled, single-arm, phase II clinical trial. A total of 26 patients with AEG will be enrolled.The primary endpoint is the pathologic complete response (pCR) rate after perioperativeneoadjuvant immunochemotherapy. Secondary outcomes of the study include the objective response rate (ORR), R0 resection rate, major pathological response (MPR) rate, and pCR rate in combined positive score(CPS) ≥5 and MSI-H populations, event-free survival (EFS), and overall survival (OS). The exploratory outcomes are the biomarkers related to therapeutic efficacy, such as PD-L1 expression, microsatellite instability (MSI), tumor mutational burden(TMB), Epstein-Barr virus(EBV) infection, and circulating tumor DNA(ctDNA).
Discussion: This trail aims to verify the efficacy and safety of the perioperative treatment regimen of anti-PD-L1 (Adebrelimab) combined with chemotherapy (capecitabine plus oxaliplatin, XELOX) for patients with resectable AEG. Considering the differences in chemotherapy regimen tolerance between Asian and Western populations, this study intends to evaluate the suitability of Adebrelimab combined with XELOX chemotherapy for the Asian population.
Trial registration: ClinicalTrials.gov: NCT06482788. The trial was prospectively registered on 22 May 2024, https://clinicaltrials.gov/study/NCT06482788
Synthesis, characterization and antibacterial properties of apatite-related zirconium, carbonate and zinc-containing calcium phosphates
Authors: Strutynska Nataliia , Dremova Lidiia D. , Livitska OksanaV. , Grynyuk Iryna I. , Vasyliuk Olga M. 
Published: November 2024

Abstract

Apatite-related zirconium, carbonate and zinc-containing calcium phosphates have been synthesized in aqueous solutions at different molar ratios Ca2+ : Zr4+ : Zn2+ : PO43- : CO32- = (10-2x-y/2-z) : x : y : (6-z) : z (x = 0.05, 0.1, 0.5 and 1.0; y = 0.1, 0.5, z = 0, 0.5) and heated to 600 oC during 2 hours. X-ray powder diffraction and FTIR spectroscopy data confirmed the formation of single phase modified apatite-related calcium phosphates with partial substitution of PO43- by CO32- in anionic sublattice (B-type). The calculated lattice parameters for prepared Zr4+, Zn2+- modified calcium phosphates correlate with amount of dopants in their composition. The sizes of prepared phosphates do not depend on composition of initial solution and vary in the range 30-45nm. The highest antimicrobial effect against Staphylococcus aureus strain was found for phosphate Ca9Zr0.5(PO4)6(OH)2 (at its adding to 10 mM). Modification of Zr-containing calcium phosphate with carbonate anion and Zn2+ decreased the Pseudomonas aeruginosa survival in ten times.
Cereal-based infant foods: Impact of thermal processing on starch properties and in vitro digestibility
Authors: Rodriguez Marianela D. , León Alberto E. , Bustos Mariela C. 
Published: November 2024

Abstract

Early-life nutrition is essential for healthy child development. Given the fact that thermal treatments modifying starch properties in cereals play a key role in improving digestibility and nutrient bioavailability, this study explored the effects of high-temperature (121 °C) and high-humidity treatment on the starch properties and digestibility of wheat, rice, and maize-based infant puree. The cereal-based purees were prepared as whole grains (TWG), whole grain flours (TWGF), or flour suspensions (TFS). Samples were analyzed for particle size, microstructure, pasting, and thermal properties. By conducting in vitro digestion mimicking, the digestive conditions of 6-12-month-old infants was performed, and starch hydrolysis was monitored. Microstructural analysis showed amyloplasts with partial or complete loss of birefringence, particularly in TFS. Thermal treatment significantly reduced peak viscosity by 41%, 56%, and 30% for TWG, TWGF, and TFS, respectively. Whereas TWG and TWGF exhibited longer peak viscosity times -suggesting enhanced mechanical and thermal stability-, TFS displayed lower thermal stability. In vitro digestion revealed a significant reduction in rapidly digestible starch (RDS) in TWG maize (0.30 g/100g vs. 4.5 g/100g in controls) and a 64% decrease in RDS in TWGF wheat. TFS increased slowly digestible starch (SDS) in maize (53%) and reduced resistant starch (RS) across all cereals. TFS also reduced phytic acid content by 30%. In conclusion, thermal treatment enhances starch digestibility and viscosity properties in a cereal-dependent manner, with potential for targeted processing to optimize infant nutrition.