bluuebunny/crossref_metadata_2025_split huggingface dataset:
Soft Tissue Sarcomas - Series of Cases in One Surgical Department
Authors: Costea R.V. , Zărnescu N. , Chirca A. , Rusu O. , Neagu S. 
Published: May 2018

Abstract
Introduction. Soft tissue sarcomas (STS) are a heterogeneous group of tumors with over 80 different subtypes that account for approximately 1-2% of adult malignancies. Primary sarcomas arise from a variety of soft tissues and bone, and include fibrous connective, fat, and smooth, or striated muscle, vascular, peripheral neural and visceral tissue. With difficulties in establishing cell origin and pathogenesis, this condition lacks an effective and durable therapy with no predictive biomarkers and rapid diagnosis. Materials and methods. We reviewed the cases of 21 patients treated in our clinic for soft tissue sarcoma over a 20-year period (1999-2018). We extracted the following information from each patient’s medical record: disease status at presentation, histological diagnosis, American Joint Committee on Cancer staging, surgical procedure, oncological outcome, length of hospitalization, and follow-up information. Results. All 21 patients (14 males and 7 females, aged between 19 and 88 years) underwent surgery and total excision with safety margins was performed with histopathological confirmation stating the tumor type and subtype. Some samples required immunohistochemistry for subtype differentiation. Chondrosarcoma and myosarcoma were the most common (5 patients). 8 patients presented local recurrence and metastatic disease with 6 cases receiving adjuvant chemotherapy. Only one patient presented for the 5-year follow-up. Conclusions. STS are a rare group of tumors with poor outcome with surgical treatment being represented by total excision. We chose to present our clinic’s experience to highlight the need for post-operative therapy advancements and to raise awareness on the difficulties in managing these cases.
Results Evaluation of Resection-Reconstruction of Knee Periarticular Tumors
Authors: Cismașiu R.S. , Bîrluțiu R.M. , Tudor A. , Pop D. , Stoica C.I. 
Published: May 2018

Abstract
Oncological resection and articular reconstruction through modular tumor prosthesis is a challenge for the surgeon, but at the same time gives the patient the certainty of keeping the function and hope for healing. Due to technical evolution, the recovery of osteoarticular post-resection tumor is today much more versatile and permissive, providing the comfort of the orthopedic oncologist surgeon during reconstruction and at the same time the patient satisfaction. Purpose of the paper. Short-term and medium-term evaluation of surgical treatment outcome of bone oncological pathogenesis of the knee with modular tumor prosthesis. Material and method. Recording based on the unique tumor registry of the Clinic in a monocentric, retrospective continuously study between 2009 and 2017, of all orthopedic oncology patients with malignant/ borderline tumors with metaphyso-epiphyseal knee periarticular involvement, beneficiaries of the resection-reconstruction with prosthesis modular tumor - a total of 21 cases. Case analysis included details of histopathological types of tumors, followed by Enneking staging, which was performed, alongside classical demographics. The Malaware oncological resection technique was followed and the learning curve and results of the prostatic modular prosthetic reconstruction were registered, considering failure for any of the following reasons: revision, necessity exhaustion of the prosthesis - infection, relapse, or amputation. The functional evaluation was based on the revised Muscular-skeletal Tumor Society Score (rMSTS). Results and discussions. Only one case of failure was registered - a periprosthetic infection. The overall rate of apparently postoperative complications followed the literature data for this type of intervention - 40-50%. Compared to amputation, the lower limb salvage process in the knee malignant tumors has proven to be cost-effective and has contributed to improving the quality of life, becoming one of the sustainable options for onco-surgical management in good cases selected. The limits of the study are determined by the relatively short duration of follow-up, and the apparently large number of complications is nevertheless included in the international statistics related to such interventions.
Maxilary Suppurative Inflammation on Chronic Treatment with Bisphosphonates for Bone Metastasis – A Case Report
Authors: Vrînceanu D. , Dumitru M. , Bănică B. , Nica A. 
Published: May 2018

Abstract
Introduction. Bisphosphonates represent a class of anti-resorbable bone care drugs that inhibit the function of active osteoclasts and reduce bone resorption. They are used in the Oncology and Hematology specialties as adjuvants in the treatment of osteolytic bone metastases and associate osteonecrosis of the maxillo-facial bones, most commonly of the mandible, as an adverse reaction. Material and method: case report. We present the case of a 65-years-old female patient, with breast cancer and bone metastasis, under chronic treatment with bisphosphonates. She presented a chronically odontogenic suppurative maxillary rhinosinusitis induced by maxillary post-extraction osteonecrosis on the background of bisphosphonate treatment and fistula in the upper right vestibule. Surgery under general anesthesia and sequestrectomy were performed. Discussion. The patient also associated coagulation disorders with mixed mechanism, adding an element of major surgical difficulty requiring a massive intraoperative transfusion with fresh refrigerated plasma to control hemostasis. Conclusions: The side effects of bisphosphonates used in the treatment of bone metastasis on the maxillofacial bones are significant. For this reason, the dental extraction in patients treated with bisphosphonates should be done with great caution and maxillary suppurative inflammation in post-extraction context in these patients should raise the suspicion of underlying bone necrosis.
Resection Reconstruction Versus Amputation in the Treatment of Malignant Tumors of the Limbs
Authors: Cristea Şt. , Popescu R. , Cuculici Şt. , Sava M. , Prundeanu A. , Groseanu F. , Georgeanu V. , Vișan R. 
Published: May 2018

Abstract
Partial or complete excision of the tumoral segment with preservation of the limb extremity in the treatment of tumors is an alternative to amputation. We present our cases with radical or wide resection and reconstruction with or without special prosthesis reconstruction. We used an evaluation and prognosis score, which included surgical stage, site of tumor, size of tumor, surgical margin, functional mobility, and activity level after surgery. Excision of the tumor with a wide margin, stable reconstruction and a good recovery is an alternative treatment to the amputation.
Management in Periacetabular Pelvic Chondrosarcoma
Authors: Cristea Şt. , Popescu R. , Cuculici Şt. , Sava M. , Vișan R. , Zamfir C. 
Published: May 2018

Abstract
The partial or complete excision of the hemipelvis with the sparing of the lower limb is an option of the treatment of pelvic chondrosarcomas and a therapeutic alternative of the interilio-abdominal disarticulation. The operation has the same indications as the interilio-abdominal disarticulation and offers a good solution for avoiding a mutilating operation. A giant periacetabular pelvic chondrosarcoma developed in Ennequin zone II and partial zone III, was resected and reconstructed with iliofemoral cooptation after complex investigations - pelvic X-ray, CT, MRI, Bioptic confirmation. The wide excision of the tumor, a stable reconstruction, and an efficient recovery are essential for a successful treatment of pelvic chondrosarcomas.
Surgical Treatment for Pulmonary Metastases of Osteosar-Coma
Authors: Rădulescu I.M. 
Published: May 2018

Abstract
Introduction. Osteosarcomas represent 40% of bone sarcomas and occur mainly in children and young adults. They are tumors with a high degree of pulmonary metastasis. Pulmonary metastases occur in about 80% of the relapsed patients after primary tumor therapy, whether or not they have received chemotherapy. As therapeutic solutions, both first intention resection of the metastasis and the post-chemotherapy resection or repeated resections in each relapse, represent satisfactory results with prolongation of survival. Material and method. The present study describes a group of 17 patients who were surgically treated for osteosarcoma with different localizations and who presented themselves in the thoracic surgery department during 2011-2016 with suspicion of pulmonary metastases. Three of them were at their second intervention for metastasis resection. Following investigations, 4 of them (23.5%) could not benefit from surgical resection of pulmonary metastases (lesional extension with postoperative vital risk or technical impossibility of metastatic excision). Surgical interventions were curative; lobectomies were performed in 4 cases (30.7%), atypical resections in 8 cases (61.6%) and one pneumonectomy (7.7%). Postoperative progression was favorable in all 13 patients. Discussions and conclusions. Surgical excision of osteosarcoma pulmonary metastases can prolong survival and sometimes even cure disease. In order to benefit from the intervention, the patient should be served by a thoracic surgery clinic in the shortest possible time after the discovery of the pulmonary nodules. Thus, the need for thoracic imaging is required in patients treated for osteosarcoma. Late presentation makes the intervention impossible, particularly because of the lesional extension in the lung parenchyma or the invasion of the adjacent structures, extension given by the number of metastases or their size.
Defect Reconstruction After Hip Tumor Resection - Our Clinical Experience
Authors: Muntean G.O. , Nica M. , Dumitrescu T.Ș. 
Published: May 2018

Abstract
Aim. Short and mid-term analysis of postoperative results after hip vicinity tumor resection and reconstruction with salvage of the lower limb. Material and method. Retrospective study on a number of 13 cases: 6 pelvis tumors, 3 femur tumors and 4 femur and pelvis tumors. 3 out of the total pelvis tumors were treated using custom pelvis reconstruction prosthesis, the other ones using bone graft and standard implants. The femoral tumors were treated using modular prosthesis and bone graft and osteosynthesis implants. Results. Short-term outcome was favorable. Conclusion. Bone defect reconstruction after hip vicinity tumor resection is a technically difficult procedure, which requires significant material resources. In terms of quality of life, the results are clearly superior compared to tumor resection with the sacrifice of the affected member.
Squamous Cell Carcinoma Developed in Chronic Osteomyelitis
Authors: Zaharia M.I. , Oproiu A.M. , Costache M. , Popescu D. , Dumitrescu N. , Varga A. 
Published: May 2018

Abstract
Introduction. Squamous cell carcinoma is the second as frequency in malignant tumors of the skin, representing 20% of this type of cancer. Inferior lip squamous carcinoma is most frequent, of 94%, because the trauma, sunburns, smoke and radiations are more frequent. Metastasis at distance in the area with chronic osteomyelitis is a rare situation. Material and method. A 78-year-old male, treated for inferior lip carcinoma, without any oncological treatment, was admitted in our clinic for a leg tumor on the anterior part, developed over a scar after osteomyelitis treated in the adolescence. The tumor growth was quick. We decided the treatment plan from the point of view of a multidisciplinary approach, plastic surgeon-orthopedistoncologist- dermatologist. A biopsy from the extraosseous tumor was performed and after the histological confirmation, the resection of the tumor block was made. For the confirmation of the bone invasion, we had to repeat the immunohistochemistry twice because the first result was negative. Until the final decision, the patient had an external fixation on the leg. A large tissue appeared on the area of resection, the aspect being suggestive for granulation. Amputation was decided after the complementary investigations and another biopsy from the granulation tissue. Results and conclusions. Squamous cell carcinoma of the lip needs prophylactic laterocervical ganglia resection for limiting metastasis.
Snake Robot Locomotion Patterns for Straight and Curved Pipe
Authors: Virgala Ivan , Lipták Tomáš , Miková Ľubica 
Published: May 2018

Abstract
In the paper the locomotion of snake robot is introduced considering locomotion in straight and curved pipe. For the straight pipe locomotion was designed traveling wave locomotion pattern with sine-like wave which expands from rear of the robot to its front. For the locomotion in curved pipe was designed approach which is based on inverse kinematic model including besides primary task also secondary tasks, namely kinematic singularities avoidance task, obstacle avoidance task and joint limit avoidance task. For final inverse kinematic model was used approach of weight matrices by which can be stated the priorities of particular tasks. Both case studies were tested by experimental snake robot in order to verify introduced methodology for locomotion in the straight and curved pipe.
Ubiquinone Plasma Levels are Correlated with Brain Natriuretic Peptide Plasma Levels in Patients with Chronic Heart Failure: The Potential of Coenzyme Q10 Combined Therapy
Authors: Sizova Zh.M. , Zakharova V.L. , Alibeyli K.A. , Medvedev O.S. , Shikh E.V. , Bolevich S.B. , Bolevich S.S. , Vorobyev S.I. , Votrin S.V. , Padalko V.V. , Novikov A.A. , Omarov I.A. 
Published: May 2018

Abstract
Despite the association of a worse HF-related clinical status with lower CoQ10 levels, the prognostic use of CoQ10 is controversial. The aim of this study is to optimize pharmacotherapy for patients with ischaemic CHF, based on the clinical and functional parameters of the heart and brain natriuretic peptide (BNP) plasma levels, which are correlated with the CoQ10 plasma levels, and to assess patient prognosis after receiving CoQ10 therapy. This prospective clinical study included 75 patients aged 56 to 63 years old with coronary heart disease (CHD) classified as class I–III according to the NYHA classification. After assessment of the clinical-instrumental characteristics of the CVD course (complaints, medical history, physical examination, a 6-minute walk test, echocardiography, and test for reactive hyperaemia), we determined the BNP level and CoQ10 plasma levels. At the same time, we assessed the efficacy of CoQ10 treatment (at a dose of 60 mg/per day) and tolerability in CVD-combined therapy during a follow-up of 12 weeks. CoQ10 supplementation in HF patients induced improvements in their functional cardiac parameters, such as the ejection fraction. Our results suggest that supplemental CoQ10 may be a useful option for effective management of heart failure and warrant future adequately powered randomized controlled trials of CoQ10 supplementation in patients with HF.
Action against smog at local government level in relation to urban public transport: evidence from selected Polish cities
Authors: Tomaszyk Mikołaj 
Published: May 2018

Abstract
All of us wish to breathe clean air. In recent years, a problem of growing importance is how to combat particulates which cause smog and are harmful to the human environment. International forums have adopted documents to prevent carpet emissions. As a result, public authorities in individual states have to tackle the tough challenge of implementing new regulations via their legal framework and administrative practice. The slogans “Clean Air” and “Right to Clean Air” trigger off grassroots movements which strive to coax the units of local government to take decisive action on a pro-ecological transport policy. While mindful of the influence of polluted air on human health, local interest groups have social control of authorities. The objectives of the article are to present the legal framework for the ‘smog alert’ and free public transport initiatives, and to analyse how local authorities have implemented free public transport, whether for all a city’s residents or just for the drivers who decide to forgo driving and have to show valid vehicle registration certificates to use public transport for free. The paper draws upon interviews and a critical review of substantive literature about the techniques for reducing smog. A scientific approach is adopted to the major body of work. Additionally, the analysis compares the pro-ecological activities of local governments in selected Polish cities. It focuses directly on the subjects managing public transport and the operators offering transport services.
STUDI PENGARUH REKONFIGURASI LOOP SCHEME TERHADAP KEANDALAN PENYULANG BLAHKIUH DAN PENYULANG PANGLAN
Authors: Yoga Bagus Widyananda , Arjana I Gede Dyana , Pemayun A.A Gede Maharta 
Published: May 2018

Abstract—To improve reliability, the do loop system reconfiguration scheme to Blahkiuh feeders and feeders Panglan, by analyzing the calculation SAIFI and SAIDI, can the economy in terms of pressing / kWh minimize the number of unsold losses. Analysis of calculation results Blahkiuh feeders and feeder reconfiguration Panglan before result Blahkiuh feeder SAIFI 16.534 times/customers/year and the results SAIDI 35.894 hours/customer/year so the numbers of unsold kWh losses from the calculation not save 227,640.841 kWh energy equivalent to Rp 318,718,182.6, while for the results obtained Panglan feeder SAIFI 23.59 times/customer/year, the results of SAIDI 87.39 hours/ customer/year and the calculation results energy not save 238,037.099 kWh equivalent to Rp 364,672,835.7. After reconfiguration can minimize the number of SAIFI / SAIDI and losses, the results obtained Blahkiuh feeder SAIFI 2,089 times/ customers/year and the results SAIDI of 4.27 hours/customer/year, results energy not save 13369.314 kWh equivalent to Rp 20,481,733.86. For Panglan feeder SAIFI results obtained 1,218 times/customers/year and the results SAIDI 1,242 hours/ customer/year, results energy not save 3880.571 kWh equivalent to Rp 5,945,033.22.

Intisari— Untuk meningkatkan keandalan maka dilakukan rekonfigurasi sistem loop scheme pada penyulang Blahkiuh dan penyulang Panglan, dengan menganalisa perhitungan SAIFI dan SAIDI, ditinjau dari segi ekonomi mampukah menekan/ memperkecil angka kerugian kWh yang tidak terjual. Hasil Analisa perhitungan penyulang Blahkiuh dan penyulang Panglan sebelum rekonfigurasi diperoleh hasil SAIFI penyulang Blahkiuh 16,534 kali/pelanggan/tahun dan hasil SAIDI 35,894 jam/pelanggan/tahun sehingga angka kerugian kWh tidak terjual dari hasil perhitungan energy not save 227.640,841 kWh setara dengan Rp 318.718.182,6, sedangkan untuk penyulang Panglan diperoleh hasil SAIFI 23,59 kali/pelanggan/tahun, hasil SAIDI 87,39 jam/pelanggan/tahun dan hasil perhitungan energy not save 238.037,099 kWh setara dengan Rp 364.672.835,7. Setelah rekonfigurasi dapat memperkecil angka SAIFI/SAIDI dan kerugian yang dialami, pada penyulang Blahkiuh didapat hasil SAIFI 2,089 kali/pelanggan/tahun dan hasil SAIDI 4,27 jam/pelanggan/tahun, hasil energy not save 13.369,314 kWh setara dengan Rp 20.481.733,86. Untuk penyulang Panglan didapat hasil SAIFI 1,218 kali/pelanggan/tahun dan hasil SAIDI 1,242 jam/pelanggan/tahun, hasil energy not save 3.880,571 kWh setara dengan Rp 5.945.033,22.

Kata Kunci : Sistem radial, Loop scheme, SAIFI/SAIDI, Energy not save
[Turnitin Chek 12% 13042017]
Efektivitas Pesan Teks Dengan Cipher Substitusi, Vigenere Cipher, dan Cipher Transposisi
Authors: Maricar M. Azman , Sastra Nyoman Putra 
Published: May 2018

Penelitian ini bertujuan untuk mengetahui efektivitas suatu keamanan pesan berbasis teks dengan metode kriptografi klasik seperti Substitusi, Vigenere, dan Transposisi. Dengan penerapan metode kriptografi, diharapkan mampu untuk meminimalisasi terjadinya penyadapan terhadap pesan teks. Ketiga metode tersebut, masing-masing akan di kombinasikan dan dibandingkan efektivitasnya berdasarkan ukuran file dan waktu proses. Terdapat tujuh kombinasi dari ketiga metode tersebut. Hasil pengujian efektivitas didapatkan hasil bahwa, ukuran file terbesar adalah kombinasi Substitusi, Vigenere, dan Transposisi yaitu 11 Kb, sedangkan yang terkecil adalah Substitusi dan juga Vigenere yaitu 5 Kb. Berdasarkan waktu proses terlama adalah Substitusi, Vigenere, dan Transposisi yaitu 1.54 detik, sedangkan yang tercepat adalah Substitusi yaitu 0.37 detik. Dari seluruh kombinasi yang ada, seluruhnya berhasil untuk proses enkripsi dan dekripsi guna mengembalikan cipher text menjadi plain text yang asli.
Rancang Bangun Alat Otomatisasi Mantram Puja Trisandya Menggunakan Mikrokontroler ATMEGA328
Authors: Utama I Nengah Raka , Agung I Gusti Agung Putu Raka , Rahardjo Pratolo 
Published: May 2018

Pengucapan Mantram Puja Trisandya dilaksanakan tiga kali sehari secara rutin oleh umat Hindu di Bali. Biasanya pengucapan memakai peralatan Elektronika dilengkapi dengan pengeras suara dan dioperasikan oleh operator secara manual. Dengan Kemajuan teknologi, aktivitas ini bisa digantikan menggunakan timer RTC yang dikendalikan dengan mikrokontroler. Perancangan rangkaiannya meliputi : Perancangan rangkaian mikrokontroler, Display, Mini MP3 Player, Keypad, Audio , dan Power Supply. Perancangan ini akan direalisasikan sehingga bisa dilakukan pengujian secara nyata. Alat ini berkerja secara otomatis dengan membandingkan jam sekarang dengan waktu pemutaran puja trisandya, apabila terjadi kecocokan data, maka mikrokontroler akan mengirimkan perintah kepada Mini MP3 Player untuk memutar file rekaman Mantram Puja Trisandya yang telah tersimpan pada mikro SD. Dari hasil penelitian didapat LCD (M1602A) mampu menampilkan huruf sesuai dengan kata-kata Mantram Puja Trisandya yang merupakan keluaran dari Mini Mp3Player dengan tepat waktu. dimana seluruh rangkaian dikendalikan dengan mikrokontroler ATmega328.
Analisa Biaya Penggunaan Bersama Jaringan Transmisi Kawasan BTDC Nusa Dua
Authors: Putra Mahadi , Giriantari Ida Ayu Dwi , Ariastina Wayan Gede 
Published: May 2018

Di seluruh dunia deregulasi sektor bisnis listrik berubah dari suatu yang terpusat dan terintegrasi menjadi suatu industri tersegmentasi berdasarkan kompetensi para pelaku bisnis tersebut. Bentuk perdagangan baru dengan akses bebas pada saluran transmisi maupun distribusi telah mendorong suatu perdagangan kompetitif antar konsumen dan pemilik pembangkit. Pada lingkungan tersebut, jaringan transmisi dianggap sebagai faktor pokok dalam pasar listrik. Pemanfaatan transmisi perusahaan lain untuk menyalurkan tenaga listrik umumnya dikenal sebagai PBJT atau Wheeling Transaction. Istilah PBJT di Indonesia dikenal dengan Penggunaan Bersama Jaringan Transmisi. Ada beberapa metode yang digunakan untuk menghitung biaya sewa transmisi dalam paper ini digunakan dua perhitungan alokasi biaya yang memungkinkan untuk diaplikasikan pada sistem kelistrikan Bali yakni, metode Postage-Stamp Rate, metode MW-mile. Pada Paper ini, akan mengaplikasikan metode Postage Stamp Rate dan MW-mile dari Wheeling Transaction dengan tujuan untuk mendapatkan perhitungan biaya sewa transmisi yang dapat diterima oleh kedua belah pihak.
Keywords— Transmisi, PBJT, Wheeling Transaction, Postage-Stamp Rate, MW-mile