bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intersection syndrome: an acute surgical disease in elite rowers
Authors: Hoy Gregory , Trease Larissa , Braybon (Deceased) Wendy 
Published: June 2019

ObjectiveIntersection syndrome is a relatively common condition in elite rowers and continuing conjecture over its pathology and best management often includes prolonged withdrawal from training and changes to the technique that may affect rowing outcomes.MethodsWe reviewed a case series in a national rowing squad and the effect on time loss produced by the condition. We reviewed the pathophysiology. We revisited the aggressive operative management put forward in the 1960s and applied it to modern rowing workload by reviewing a retrospective case series of six international rowers who had early surgical intervention.ResultsApproximately 5% of the squad suffered intersection syndrome during a 3-year period. The effect on training time was between 20% and 40% of their training time in the period. Using our understanding of the pathology as a true tendinitis of the second wrist compartment caused by fascial compression from hypertrophied first compartment muscles, we advocated earlier surgery and almost immediate return to training, which occurred at a median of 7 days postsurgery. We had successful return in five of six rowers in an accelerated programme to minimise muscle wasting and technique modification caused by the condition, achieving career goals in a matter of weeks after surgical intervention.ConclusionsWe encourage early surgical management of intersection syndrome of the wrist to allow almost immediate return to training, and therefore interfere less with technique modification and time out of the water. This minimises career disruption in the elite rowing community.
Lycopene Inhibits Smoke-Induced Chronic Obstructive Pulmonary Disease and Lung Carcinogenesis by Modulating Reverse Cholesterol Transport in Ferrets
Authors: Mustra Rakic Jelena , Liu Chun , Veeramachaneni Sudipta , Wu Dayong , Paul Ligi , Chen C.-Y. Oliver , Ausman Lynne M. , Wang Xiang-Dong 
Published: June 2019

Abstract
Chronic obstructive pulmonary disease (COPD) and lung cancer share the same etiologic factor, cigarette smoking. Higher consumption of dietary lycopene has been associated with lower risks of COPD and lung cancer in smokers. We investigated whether lycopene feeding protects against COPD and lung cancer in ferrets, a nonrodent model that closely mimics cigarette smoke (CS)-induced chronic bronchitis, emphysema, and lung tumorigenesis in human. We also explored whether the protective effect of lycopene is associated with restoring reverse cholesterol transport (RCT), a key driver in persistent inflammation with CS exposure. Ferrets (4 groups, n = 12–16/group) were exposed to a combination of tobacco carcinogen (NNK) and CS with or without consuming lycopene at low and high doses (equivalent to ∼30 and ∼90 mg lycopene/day in human, respectively) for 22 weeks. Results showed that dietary lycopene at a high dose significantly inhibited NNK/CS-induced chronic bronchitis, emphysema, and preneoplastic lesions, including squamous metaplasia and atypical adenomatous hyperplasia, as compared with the NNK/CS alone (P &lt; 0.05). Lycopene feeding also tended to decrease the lung neoplastic lesions. Furthermore, lycopene feeding significantly inhibited NNK/CS-induced accumulation of total cholesterol, and increased mRNA expression of critical genes related to the RCT (PPARα, LXRα, and ATP-binding cassette transporters ABCA1 and ABCG1) in the lungs, which were downregulated by the NNK/CS exposure. The present study has provided the first evidence linking a protective role of dietary lycopene against COPD and preneoplastic lesions to RCT-mediated cholesterol accumulation in lungs.
Assessment of 2D ultrasound fluid volume estimation accuracy in different shaped objects: an in vitro study
Authors: Kodikara Iroshani , Abeysekara Iroshini , Gamage Dhanusha , Ilayperuma Isurani 
Published: June 2019

Background Volume estimation of organs using two-dimensional (2D) ultrasonography is frequently warranted. Considering the influence of estimated volume on patient management, maintenance of its high accuracy is empirical. However, data are scarce regarding the accuracy of estimated volume of non-globular shaped objects of different volumes. Purpose To evaluate the volume estimation accuracy of different shaped and sized objects using high-end 2D ultrasound scanners. Material and Methods Globular (n=5); non-globular elongated (n=5), and non-globular near-spherical shaped (n=4) hollow plastic objects were scanned to estimate the volumes; actual volumes were compared with estimated volumes. T-test and one-way ANOVA were used to compare means; P<0.05 was considered significant. Results The actual volumes of the objects were in the range of 10–445 mL; estimated volumes ranged from 6.4–425 mL ( P=0.067). The estimated volume was lower than the actual volume; such volume underestimation was marked for non-globular elongated objects. Regardless of the scanner, the highest volume estimation error was for non-globular elongated objects (<40%) followed by non-globular near-spherical shaped objects (<23.88%); the lowest was for globular objects (<3.6%). Irrespective of the shape or the volume of the object, volume estimation difference among the scanners was not significant: globular (F=0.430, P=0.66); non-globular elongated (F=3.69, P=0.064); and non-globular near-spherical (F=4.00, P=0.06). A good inter-rater agreement (R=0.99, P<0.001) and a good correlation between actual versus estimated volumes (R=0.98, P<0.001) were noted. Conclusion The 2D ultrasonography can be recommended for volume estimation purposes of different shaped and different sized objects, regardless the type of the high-end scanner used.
Participant perceptions of virtual simulation to develop non-technical skills in health professionals
Authors: Peddle Monica 
Published: June 2019

Background Research has identified that virtual simulations may be effective in developing non-technical skills including communication, teamwork and decision making. However, little is known about how participants perceive learning non-technical skills via engagement in virtual simulation. Aims The aim of this research was to investigate participant perceptions and the learning experiences when engaging in virtual simulations focused on developing non-technical skills. Method A descriptive exploratory approach was used. An online voluntary survey collected qualitative extended responses from participants after each virtual simulation. Ethics approval was obtained for the research and guidelines adhered to throughout the study. Results A total of 675 responses were obtained. Participants perceive that engaging with the virtual simulation made them aware of non-technical skills including communication, teamwork, decision making, critical thinking and problem solving, and, to a lesser extent, situational awareness. Additional categories of learning, clinical practice and limitations were identified. Conclusions Engaging in virtual simulation can develop awareness of non-technical skills, as well as confidence and vigilance in practice and mindfulness of a person-centred approach to healthcare. Engaging in virtual simulation may support change in the professional performance of the participants through role modelling and learning through error.
Exercise-based cardiac rehabilitation in patients with reduced left ventricular ejection fraction: The Cardiac Rehabilitation Outcome Study in Heart Failure (CROS-HF): A systematic review and meta-analysis
Authors: Bjarnason-Wehrens Birna , Nebel R , Jensen K , Hackbusch M , Grilli M , Gielen S , Schwaab B , Rauch B ,   for the German Society of Cardiovascular Prevention and Rehabilitation (DGPR)
Published: June 2019

BackgroundIn heart failure with reduced left ventricular ejection fraction (HFrEF) patients the effects of exercise-based cardiac rehabilitation on top of state-of-the-art pharmacological and device therapy on mortality, hospitalization, exercise capacity and quality-of-life are not well established.DesignThe design of this study involved a structured review and meta-analysis.MethodsEvaluation of randomised controlled trials of exercise-based cardiac rehabilitation in HFrEF-patients with left ventricular ejection fraction ≤40% of any aetiology with a follow-up of ≥6 months published in 1999 or later.ResultsOut of 12,229 abstracts, 25 randomised controlled trials including 4481 HFrEF-patients were included in the final evaluation. Heterogeneity in study population, study design and exercise-based cardiac rehabilitation-intervention was evident. No significant difference in the effect of exercise-based cardiac rehabilitation on mortality compared to control-group was found (hazard ratio 0.75, 95% confidence interval 0.39–1.41, four studies; 12-months follow-up: relative risk 1.29, 95% confidence interval 0.66–2.49, eight studies; six-months follow-up: relative risk 0.91, 95% confidence interval 0.26–3.16, seven studies). In addition there was no significant difference between the groups with respect to ‘hospitalization-for-any-reason’ (12-months follow-up: relative risk 0.79, 95% confidence interval 0.41–1.53, four studies), or ‘hospitalization-due-to-heart-failure’ (12-months follow-up: relative risk 0.59, 95% confidence interval 0.12–2.91, four studies; six-months follow-up: relative risk 0.84, 95% confidence interval 0.07–9.71, three studies). All studies show improvement of exercise capacity. Participation in exercise-based cardiac rehabilitation significantly improved quality-of-life as evaluated with the Kansas City Cardiomyopathy Questionnaire: (six-months follow-up: mean difference 1.94, 95% confidence interval 0.35–3.56, two studies), but no significant results emerged for quality-of-life measured by the Minnesota Living with Heart Failure Questionnaire (nine-months or more follow-up: mean difference –4.19, 95% confidence interval –10.51–2.12, seven studies; six-months follow-up: mean difference –5.97, 95% confidence interval –16.17–4.23, four studies).ConclusionNo association between exercise-based cardiac rehabilitation and mortality or hospitalisation could be observed in HFrEF patients but exercise-based cardiac rehabilitation is likely to improve exercise capacity and quality of life.
Superiority Claims for Spinal Devices: A Systematic Review of Randomized Controlled Trials
Authors: Golish S. Raymond , Groff Michael W. , Araghi Ali , Inzana Jason A. 
Published: June 2019

Study Design: Systematic review. Objectives: Superiority claims for medical devices are commonly derived from noninferiority trials, but interpretation of such claims can be challenging. This study aimed to ( a) establish the prevalence of noninferiority and superiority designs among spinal device trials, ( b) assess the frequency of post hoc superiority claims from noninferiority studies, and ( c) critically evaluate the risk of bias in claims that could translate to misleading conclusions. Methods: Study bias was assessed using the Cochrane Risk of Bias Tool. The risk of bias for the superiority claim was established based on post hoc hypothesis specification, analysis of the intention-to-treat population, post hoc modification of a priori primary outcomes, and sensitivity analyses. Results: Forty-one studies were identified from 1895 records. Nineteen (46%) were noninferiority trials. Fifteen more (37%) were noninferiority trials with a secondary superiority hypothesis specified a priori. Seven (17%) were superiority trials. Of the 34 noninferiority trials, 14 (41%) made superiority claims. A medium or high risk of bias was related to the superiority claim in 9 of those trials (64%), which was due to the analyzed population, lacking sensitivity analyses, claims not being robust during sensitivity analyses, post hoc hypotheses, or modified endpoints. Only 4 of the 14 (29%) noninferiority studies provided low bias in the superiority claim, compared with 3 of the 5 (60%) superiority trials. Conclusions: Health care decision makers should carefully evaluate the risk of bias in each superiority claim and weigh their conclusions appropriately.
Textural Changes in Hot Compression of Disintegrated Melt Deposition (DMD)–Processed AZ31-1Ca-1.5 vol. % Nano-Alumina Composite
Authors: Rao K. P. , Dharmendra C. , R. K. Prasad Y. V. , Suresh K. , Gupta M. 
Published: June 2019

Abstract
The development of texture in AZ31-1Ca-1.5 volume percent (vol. %) nano-alumina composite subjected to uniaxial compression is studied over large ranges of temperature and strain rate, and correlated with operative slip systems in the various domains of its processing map. The initial rod, synthesized via disintegrated melt deposition and subsequently extruded, has a fine grain size (2–3 μm) and basal texture with (0001) planes parallel to the extrusion direction. The processing map exhibits four domains: Domain 1: 250–350°C and 0.0003–0.01 s−1, Domain 1A: 350–410°C and 0.0003–0.01 s−1, Domain 2: 410–490°C and 0.002–0.2 s−1, and Domain 3: 325–410°C and 0.6–10 s−1. Microstructures in these four domains revealed dynamic recrystallization, although the mechanisms of slip and recovery are different. In Domain 1, basal slip is the dominating mechanism that produced strong basal textures. Recovery occurs via dislocation climb controlled by lattice self-diffusion, which is promoted by the fine grain size in the starting material. In Domain 1A, prismatic slip is the major deformation mechanism and the basal texture is reduced, and the prismatic planes are tilted towards the compression axis. At higher temperatures of Domain 2, in addition to basal and prismatic slip, pyramidal slip occurs, and cross-slip among the multiple intersecting slip planes is the recovery mechanism that destroys the initial basal texture. At higher strain rates, at which Domain 3 occurs, non-basal slip (prismatic and pyramidal) activity is higher than that for basal slip, and the basal texture is reduced, giving way to favorable prismatic slip orientations. The recovery in this domain occurs via dislocation climb, which is controlled by grain boundary self-diffusion. The activation parameters, tensile ductility, and fracture features further support the conclusions on the rate-controlling mechanisms occurring in each domain.
Effect of Sn Substitution on the Thermoelectric Properties of Nanostructured Bulk Bi2-xSbxTe3 Alloy.
Authors: Santhanam Sumithra. , Takas Nathan J. , Nolting Westly M. , Poudeu Pierre F.P. , Stokes Kevin L. 
Published: June 2019

ABSTRACTThe carrier concentration and electronic transport properties in Bi2-xSbxTe3 alloy can be tuned by varying the Bi to Sb ratio, for high thermoelectric figure of merit. The concentration of intrinsic antisite defects in these alloys is also known to change with Bi to Sb ratio. Here we report the thermoelectric figure of merit of Sn doped Bi0.5Sb1.5Te3 alloy. Different atomic percentages of Sn was substituted at Bi/Sb site in Bi0.5Sb1.5Te3 alloy, synthesized by planetary ball milling. The electrical conductivity decreases with increasing Sn doping but for higher Sn content the electrical conductivity increases compared to undoped alloy. The Seebeck coefficient changes in accordance to electrical conductivity, resulting in small decrease in power factor for highest Sn doping. The lattice thermal conductivity shows a systematic decrease, with increasing Sn concentration resulting in a significant thermal conductivity reduction. Hence an increase in thermoelectric figure of merit could be achieved for the highest Sn (3at%) doping in Bi0.5Sb1.5Te3 alloy as compared to undoped alloy.
Near-field Nanoscale Investigation of Optical Properties of Bi2Se3 Thin-films
Authors: Grefe Sarah E. , Tan Malinda , Derakhshan Shahab , Abate Yohannes 
Published: June 2019

ABSTRACTBi2Se3 thin films are imaged in the near-field using spectroscopic scattering type near-field optical microscopy (s-SNOM) at mid infrared laser wavelength region (9-11μm). Single phases Bi2Se3 thin film structures were prepared by mechanical exfoliation on silicon wafers. We report size and wavelength dependent near-field interaction contrasts in both optical amplitude and phase. We show that near-field optical imaging allows material specific identification and characterization of Bi2Se3 exfoliated samples including the confirmation of residual tape presence or removal in stacked films. We describe an alternative “shear exfoliation” sample preparation method which reliably deposits Bi2Se3 without the possibility of adhesive contaminants.
Structural and Magnetic study of Al3+ doped Ni0.75Zn0.25Fe2-xAlxO4 nanoferrites
Authors: Wang L. , Rai B. K. , Mishra S. R. 
Published: June 2019

AbstractNanostructured Al3+ doped Ni0.75Zn0.25Fe2-xAlxO4 (x = 0.0,0.2,0.4,0.6,0.8, and 1.0) ferrites were synthesized via wet chemical method. X-ray diffraction, transmission electron microscopy, and magnetization measurements have been used to investigate the structural and magnetic properties of spinel ferrites calcined at 950 °C .With the doping of Al3+, the particle size of Ni0.75Zn0.25Fe2-xAlxO4 first increased to 47 nm at x = 0.4 and then decreased down to 37 nm at x = 1. Saturation magnetization decreased linearly with Al3+ due to magnetic dilution. The coercive field showed an inverse dependence on the particle size of ferrites.
Flame synthesis of MgO nanoparticles in a FASP Reactor
Authors: De Falco Gianluigi , Morgan Alexander , Commodo Mario , Minutolo Patrizia , D’Anna Andrea 
Published: June 2019

ABSTRACTThe purpose of this work is the development and control of a high temperature reactor for the production of engineered nanoparticles, taking advantage from our previous studies on combustion-generated fine carbonaceous particles. The reactor consists of a laminar premixed flame, homogenously doped with monodisperse droplets of metal precursors dissolved or dispersed in volatile solvents. The droplets are generated by a vibrating orifice aerosol generator, and injected directly into the burner. Fuel-lean and stoichiometric flames allow producing pure metal oxide particles of nanometric sizes.Particles are collected by thermophoresis inserting a cold substrate in the flame by means of a pneumatic actuator. Morphological and dimensional analysis are performed on the collected particles by Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM). SEM and AFM allow inferring both qualitative and quantitative information on many physical properties including size, morphology, surface texture and roughness.Experimental results have been obtained from a premixed stoichiometric flame of ethylene and air, doped with 75 microns droplets of magnesium nitrate hexahydrate dissolved in ethanol. Roughly monodisperse magnesium oxide particles, having a desired size ranging from 50 nm down to 7 nm, have been produced by altering the precursor concentration in the solution and the residence time of the synthesis process.
Prediction of the radiative properties of reconstructed alpha-SiC foams used for concentrated solar applications
Authors: Rousseau Benoit , Guevelou Simon , Domingues Gilberto , Vicente Jerome , Caliot Cyril , Flamant Gilles 
Published: June 2019

ABSTRACTA SiC-based ceramic foam applied in solar thermal processes was characterized in detail in terms of its textural parameters and its radiative properties. Scanning electron microscopy and x-ray µ-tomography were first performed to investigate the 3D texture of the sample at several length scales. Infrared reflectance microscopy was also applied to probe the local optical responses on the struts constituting the foam. Based on the whole set of experimental data, a numerical tool (C++) was implemented to reconstruct virtual SiC foams. A Monte Carlo Ray Tracing code (iMorphRad, C++) was then used to compute the normal spectral emittance for the real SiC foam and for another reconstructed SiC foam with similar textural features. The two numerically determined emittances were then compared with previous infrared spectroscopy experimental measurements. This numerical procedure enables us to propose a methodology for the design of SiC foams with prescribed radiative properties.
Global trends and patterns in material use
Authors: Krausmann Fridolin , Schaffartzik Anke , Mayer Andreas , Gingrich Simone , Eisenmenger Nina 
Published: June 2019

ABSTRACTHumanity currently extracts almost 70 billion tons of materials per year. During the last century global materials extraction and use have increased by one order of magnitude. Growth accelerated in the last decade, when materials extraction grew with the global economy at an annual rate of 3.6%. For sustainable development it is of key importance to understand the spatial and temporal dynamics of global material use and the underlying drivers. This paper explores changes in global material use during the last century from a systemic perspective based on the concept of socio-economic metabolism.In recent years socio-economic (or, more narrowly termed industrial) metabolism became a prominent concept in sustainability science as many global sustainability problems are directly associated with humanities growing demand for raw materials and their transformation into wastes and emissions after processing and use. Material Flow Analysis (MFA) is one of the approaches available to study social metabolism. It provides data and headline indicators for resource use in national economies and is widely used in science and by policy makers.This paper presents results from a global material flow analysis and explores long term the development of global material extraction and use. It shows that in particular the period after WWII was characterized by a rapid expansion of resource use, driven by both population and economic growth. Within this period a shift from the dominance of renewable biomass towards mineral and fossil materials, which now account for 70% of all used materials, was observed. Overall, material use increased at a slower pace than the global economy, but faster than world population. As a consequence, material intensity (i.e. the amount of materials required per unit of GDP) declined throughout the 20th century, while materials use per capita doubled. The use of materials is by no means equally distributed around the globe. Per capita material use varies by a factor of 20 across countries. At the turn of the millennium, 15% of the global population living in industrialized countries were using half of all mineral and fossil resources; in contrast, the least developed countries, inhabiting 11% of global population, appropriated only 1% of these strategically important materials. In recent years, however, the emerging economies gained significance as drivers for physical growth. So far there is no evidence that growth of global materials use is slowing down. The paper discusses the implications of the results from the material flow analysis for sustainable development.
Development of Chalcogenide Thin Film Materials for Photoelectrochemical Hydrogen Production
Authors: Gaillard Nicolas , Prasher Dixit , Kaneshiro Jess , Mallory Stewart , Chong Marina 
Published: June 2019

ABSTRACTIn the present communication, we report our efforts to integrate chalcogenide-based photoelectrochemical (PEC) materials into a standalone device capable of water-splitting using sunlight as the only source of energy. More specifically, the PEC performances of copper gallium diselenide are presented. First, a brief introduction to the material microstructural characteristics is presented. Then, the PEC properties are discussed, including incident-photonto-current efficiency (>60% in the visible), Faradaic efficiency (uncatalyzed, 86%) and durability (400 hours). Finally, we report the solar-to-hydrogen benchmark efficiency (3.7%) of a device made of a CuGaSe2 photocathode and a-Si solar cells measured in a 2-electrode configuration using a RuO2 counter electrode.