bluuebunny/crossref_metadata_2025_split huggingface dataset:
An efficient frequency-domain model for quick load analysis of floating offshore wind turbines
Authors: Pegalajar-Jurado Antonio , Borg Michael , Bredmose Henrik 
Published: October 2018

Abstract. A model for Quick Load Analysis of Floating wind turbines (QuLAF) is
presented and validated here. The model is a linear, frequency-domain,
efficient tool with four planar degrees of freedom: floater surge, heave,
pitch and first tower modal deflection. The model relies on state-of-the-art
tools from which hydrodynamic, aerodynamic and mooring loads are extracted
and cascaded into QuLAF. Hydrodynamic and aerodynamic loads are pre-computed
in WAMIT and FAST, respectively, while the mooring system is linearized
around the equilibrium position for each wind speed using MoorDyn. An
approximate approach to viscous hydrodynamic damping is developed, and the
aerodynamic damping is extracted from decay tests specific for each degree of
freedom. Without any calibration, the model predicts the motions of the
system in stochastic wind and waves with good accuracy when compared to FAST.
The damage-equivalent bending moment at the tower base is estimated with
errors between 0.2 % and 11.3 % for all the load cases
considered. The largest errors are associated with the most severe wave
climates for wave-only conditions and with turbine operation around rated
wind speed for combined wind and waves. The computational speed of the model
is between 1300 and 2700 times faster than real time.
Quality Measures in Foot and Ankle Care
Authors: Xiong Grace , Bennett Chase G. , Chou Loretta , Kamal Robin N. 
Published: October 2018

Background:
Quality measures may be operationalized in payment models or quality reporting programs to assess foot and ankle surgeons, but if existing measures allow accurate representation of a foot and ankle surgeon's practice is unclear.

Methods:
National quality measures databases, clinical guidelines, and MEDLINE/PubMed were systematically reviewed for quality measures relevant to foot and ankle care. Measures meeting internal criteria were categorized by clinical diagnosis, National Quality Strategy priority, and Donabedian domain.

Results:
Of 12 quality measures and 16 candidate measures, National Quality Strategy priorities most commonly addressed “Effective Clinical Care” (n = 19) and “Communication and Coordination of Care” (n = 6). Donabedian classifications addressed were process (n = 25) and outcome (n = 3). Diabetic foot care was most commonly addressed (n = 18).

Conclusions:
Available foot and ankle quality measures are limited in number and scope, which may hinder appropriate assessment of care, analysis of trends, and quality improvement. Additional measures are needed to support the transition to a value-based system.

Level of Evidence:
Level I
The impact of marriage on the overall survival of prostate cancer patients: A Surveillance, Epidemiology, and End Results (SEER) analysis
Authors: Liu Yu , Xia Qi , Xia Jianling , Zhu Hua , Jiang Haihong , Chen Xiangjian , Zheng Yuancai , Zhang Fangyi , Li Shi 
Published: October 2018

Introduction: Marital status has long been associated with positive patient outcomes in several malignances; however, little is known about its influence on prostate cancer. We analyzed data from the Surveillance, Epidemiology, and End Results (SEER) database to evaluate whether married patients with prostate cancer had a better prognosis than unmarried patients.
Methods: We identified 824 554 patients diagnosed with prostate cancer between 1973 and 2012 in the SEER database. Using the Cox proportional hazard models, we analyzed the impact of marital status (single, married, divorced/separated, and widowed) on survival after diagnosis with prostate cancer. Chi-square tests were used to analyze the association between marital status and other variables, and the Kaplan-Meier method was used to estimate survival curves.
Results: Married men were more likely to be diagnosed with a lower Gleason score and undergo surgery than patients in the other groups (p<0.001). The married group had a lower risk of mortality caused by prostate cancer than the other groups. The five-year survival rate for married patients was higher than that for patients in the other groups.
Conclusions: Marital status is a prognostic factor for the survival of prostate cancer patients, as being married was associated with better outcomes.
De aanval is de beste verdediging
Authors: Steenwijk P. , Nelen H. 
Published: October 2018

De aanval is de beste verdediging – Het indammen van witwaspraktijken in de professionele voetballerij
Complexe geldstromen, irrationele prijsvorming van transfers en het ontbreken van gerichte wetgeving maken het betaald voetbal aantrekkelijk voor het witwassen van crimineel geld. Bij de belangrijkste stakeholders is het besef inmiddels doorgedrongen dat het noodzakelijk is de witwasbestrijding binnen de sector serieus aan te pakken. De preventieve toetsing van grote investeerders in clubs door de KNVB en de aanbevelingen van De Nederlandsche Bank aan banken om alert te zijn op witwasrisico’s bij voetbalklanten zijn stappen in de goede richting.Voor een effectieve aanpak wordt gepleit voor de invoering van een periodieke integriteitstoetsing van eigenaren en leidinggevenden van betaaldvoetbalorganisaties, in combinatie met een breder screeningsinstrument, zoals is opgenomen in de Wet Bibob.
The Interrelationship between Competitiveness and Value Chain: Case Study in a Metal-Mechanical Company in Santa Catarina
Authors: Machado Nelson Santos , Casagrande Juceli , Roman Darlan José , Carvalho Carlos Eduardo 
Published: October 2018

Objective: To understand the interrelationship between the analysis of competitiveness and the value chain for the strategic diagnosis of a company in the metal-mechanical industry and its importance for the identification of a competitive advantage. Method: This study is predominantly a qualitative, descriptive and interpretative approach. Data collection was done through semi-structured interviews with four company executives as well as documentary research. The analysis was based on the content analysis technique. Originality / Relevance: Competitive advantage is built from the adequacy of the competences developed by the company with the demands of the environment. This research sought to integrate a real case and analysis of the competitive forces along with the analysis of the value chain, with a systemic look of the company’s ability to meet the target audience’s needs. Results: We found that the company built a competitive advantage directly linked to the adequacy of its value chain, achieved through automation and the effectiveness of the primary activities of internal logistics, production, external logistics and sales operations. The primary competitive advantage is based on the differentiation of a robust quality that guarantees customer satisfaction. While the company does not achieve cost leadership in the industry, it manages to be competitive due to the level of automation and consistency of processes. Theoretical / methodological contributions: The proposal to establish the intersection between value chain analysis and the five competitive forces model to identify the competitive advantage was methodologically adequate and relevant for the company under study.
Strategy First, Execution Second: Why Life Science Entrepreneurs Should Adopt a Top-Down Mindset Early
Authors: Bouta Echoe , Ben-Joseph Oded 
Published: October 2018

Despite the dedication of the management team and board to a company’s success, an often overlooked component is the dynamics of the segment in which the company operates. In an effort to demonstrate the importance of the external view and how segment dynamics are likely to significantly impact the reality of companies, we analyzed recent data in the three-year period between 2015 and 2017 pertaining to financing events, M&A transactions and initial public offerings (IPO) in three separate sectors: therapeutic devices, oncology therapeutics and antibiotics. The analysis presented will provide management with a good estimation as to the required capital to achieve value-add milestones as well as the anticipated return on investment. These examples demonstrate the fundamentally different dynamics of three sectors, which will impact the most probable path to liquidity of companies in those sectors. Therapeutic devices have to often get regulatory approval prior to an exit where exits happen earlier in clinical development for the oncology therapeutics sector. Despite the high unmet need, there have been limited exits in the antibiotics sector. In all cases, return on investment is greater when the company’s exit included being acquired versus an IPO. This data demonstrates that exit opportunities are largely sector-dependent and suggests substituting external formal thinking, market-driven evaluation and analysis for inward-looking and biased judgment will being beneficial crafting a mature business case as well increasing the probability of success.
Peripheral body temperature impairment in individuals with type 1 diabetes mellitus
Authors: Barone Mark Thomaz Ugliara , Gonçalves Bruno , Menna-Barreto Luiz 
Published: October 2018

Objective: The aim of the present study was to evaluate the peripheral temperature rhythmicity and control in individuals with type 1 diabetes mellitus.
Methods: Twelve non-obese adults (20-40 years old) with type 1 diabetes mellitus (T1D) and eight control individuals, matched for age and BMI, wore a wrist temperature recorder for 10 consecutive days. Recorded data were aggregated to calculate M10 (ten hours of highest temperature) and L5 (five hours of lowest temperature) of wrist temperature values for both groups.
Results: Mean wrist temperature and M10 were not different when comparing the groups. The wrist temperature amplitude was reduced in the T1D group (p=0.039), due to a higher L5 (p=0.038).
Discussion: While the higher L5 observed in T1D could be explained by less efficient heat dissipation, the amplitude flattening coincides with that observed in elderly.
Generalized Anxiety disorder but not depression is associated with insomnia: a population based study
Authors: Khan Imran Wasfi , Juyal Ruchi , Shikha Deep , Gupta Ravi 
Published: October 2018

Background: Insomnia is a common problem, however, its prevalence has never been examined in Indian population. Moreover, a number of psychiatric disorders have been found to be associated with insomnia in clinical population, but this association has scarcely been examined in general population.
Methods: This epidemiological study was done in an urban and a rural population. Subjects were selected using Kish method. After obtaining informed consent, psychiatric disorders were diagnosed using Hindi version of Mini International Neuropsychiatric Interview. Hindi version of Insomnia Severity Index was used to diagnose insomnia.
Results: 1700 subjects were included in this study. In this study, prevalence of insomnia was 10.3%. Its prevalence increased with increasing years of education (p=0.009). Insomnia was more frequent in subjects living in joint families (p<0.001), having higher education (p=0.009), those who were separated (p<0.001), among subjects belonging to middle socio-economic status (p<0.001) and in urban population compared to semi-urban and rural population (p<0.001). Insomnia was also more frequent among subjects with major depressive disorder, generalized anxiety disorder, alcohol dependence, cannabis dependence and tobacco use. However, binary logistic regression analysis showed that only higher education, unemployment, generalized anxiety disorder and tobacco use were associated with insomnia.
Conclusion: Insomnia in general population is associated with higher education, unemployment, generalized anxiety disorders and tobacco use.
Finnish cattle and pig farmers’ perceptions of animal welfare inspections
Authors: Väärikkälä S , Artukka S-M , Hänninen L , Nevas M 
Published: October 2018

AbstractThe aim of this study was to broaden the understanding of Finnish cattle and pig farmers’ perceptions of the on-site animal welfare inspections carried out by official authorities in livestock farms. The study was conducted using an electronic questionnaire, aimed at 500 Finnish cattle and 500 pig farmers. Responses were received from 96 cattle farmers and 105 pig farmers, of which 20 and 55, respectively, had undergone an animal welfare inspection. It was found that most of the farmers recognised the need for animal welfare inspections, but also that a more negative attitude was prevalent among farmers who had undergone these inspections. The inspection itself was a far more negative experience if the farmer had not understood the reason for the inspection, no opportunity existed to be heard, or the findings of the report were found to be unclear. The results suggest that although the farmers generally approve of inspections, their own negative experiences affect their perceptions. Moving forward, efforts should be made by inspectors to enhance the level of communication, thereby ensuring the findings of the report are clear to the farmer.
L’école publique au Madawaska et la politique assimilationniste du Maine (1842–1920)
Authors: Sance Élisa 
Published: October 2018

Après l’établissement de la frontière internationale entre le Maine et le Nouveau-Brunswick en 1842, l’État du Maine s’est engagé dans une politique d’assimilation des francophones de la vallée du Saint-Jean. Territoire contesté pendant de nombreuses années, la région du Madawaska disposait en 1842 d’institutions reflétant le mode de fonctionnement de cette communauté restée jusqu’alors relativement autonome. La barrière de la langue, l’identité de la communauté francophone du Madawaska, ainsi que la différence entre les institutions du Maine et celle du Madawaska ont constitué autant de freins à l’américanisation de la vallée du Saint-Jean.
L’école publique est un des moyens d’encourager sinon l’assimilation, au moins l’acculturation. Cet article examine les répercussions de la politique assimilationniste du Maine sur l’établissement du système scolaire public au Madawaska. Il s’intéresse particulièrement à la formation des enseignants et aux aménagements spécifiques du système scolaire consentis par l’État du Maine dans le but de faire progresser sa politique assimilationniste.
Coordinative control of G2/M phase of the cell cycle by non-coding RNAs in hepatocellular carcinoma
Authors: Shi Jun , Ye Guangqiang , Zhao Guoliang , Wang Xuedong , Ye Chunhui , Thammavong Keooudone , Xu Jing , Dong Jiahong 
Published: October 2018

Objective
To investigate the interaction of non-coding RNAs (ncRNAs) in hepatocellular carcinoma.

Methods
We compared the ncRNAs and mRNAs expression profiles of hepatocellular carcinoma and adjacent tissue by microarray and RT-PCR. The relationship between different ncRNAs and mRNA was analyzed using bioinformatics tools. A regulatory model of ncRNAs in hepatocellular carcinoma cells was developed.

Results
A total of 1,704 differentially expressed lncRNAs, 57 miRNAs, and 2,093 mRNAs were identified by microarray analyses. There is a co-expression relationship between two ncRNAs (miRNA-125b-2-3p and lncRNA P26302). Bioinformatics analysis demonstrated cyclin-dependent kinases 1 and CyclinA2 as potential targets of miR-125b-2-3p and Polo-like kinase 1 as potential target of lncRNAP26302. All three gene are important components in the G2/M phase of cell cycle. Subsequently real-time polymerase chain reaction (PCR) studies confirmed these microarray results.

Conclusion
MiR-125b-2-3p and lncRNAP26302 may affect the G2/M phase of the cell cycle through the regulation of their respective target genes. This study shows a role of ncRNAs in pathogenesis of hepatocellular carcinoma at molecular level, providing a basis for the future investigation aiming at early diagnosis and novel treatment of hepatocellular carcinoma.
CONCEPÇÕES E PRÁTICAS DOCENTES NA FORMAÇÃO DO ALUNO LEITOR E ESCRITOR
Authors: Zaider Penteado Dienifer , Bona Josefi Ângela Helena 
Published: October 2018

Este trabalho objetivou analisar as práticas de ensino desenvolvidas no processo de alfabetização e sua influência na formação de escritores e leitores. Observou-se a relação entre o que se propõe na sala de aula e como se expressam as concepções de ensino e aprendizagem no discurso dos professores. A pesquisa foi orientada por uma abordagem qualitativa interpretativa, e realizada em uma escola municipal de Guarapuava-PR, mediante entrevistas e observações de aulas, por um ano, envolvendo professoras do 1º ano do ensino fundamental. Constatou-se uma distorção entre a concepção interacionista, dos discursos das professoras, e a sua prática mecanicista, que prejudica a formação do usuário da lingagem escrita.
The impact of seductive details and signaling on analogical transfer
Authors: Abercrombie Sara , Hushman Carolyn J. , Carbonneau Kira J. 
Published: October 2018

SummaryThis study tests if the seductive details effect on transfer is mitigated by signaling. Preservice teachers (N = 73) were randomly assigned on the basis of two factors, signaling and seductive details. After learning about principles of effective feedback, participants reflected on a narrative text case illustrating the instructional material that either contained or did not contain signals (highlighting key base text) and/or seductive details (interesting but extraneous details). Whereas no group differences for signaling, or signaling by seductive details interaction were found, a significant main effect for seductive details on transfer was found, Cohen's d = 0.51. These results suggest seductive details embedded in narrative cases negatively impact analogical transfer, and the effect is not mitigated by the inclusion of signaling. This lends support to the diversion hypothesis of seductive details, which suggests that seductive details damage learning by preventing meaningful encoding in appropriate schema.
A Solid‐State Hard Microfluidic–Nanopore Biosensor with Multilayer Fluidics and On‐Chip Bioassay/Purification Chamber
Authors: Varongchayakul Nitinun , Hersey Joseph S. , Squires Allison , Meller Amit , Grinstaff Mark W. 
Published: October 2018

AbstractSolid‐state nanopores are an emerging biosensor for nucleic acid and protein characterization. For use in a clinical setting, solid‐state nanopore sensing requires sample preparation and purification, fluid handling, a heating element, electrical noise insulators, and an electrical readout detector, all of which hamper its translation to a point‐of‐care diagnostic device. A stand‐alone microfluidic‐based nanopore device is described that combines a bioassay reaction/purification chamber with a solid‐state nanopore sensor. The microfluidic device is composed of the high‐temperature/solvent resistance Zeonex plastic, formed via micromachining and heat bonding, enabling the use of both a heat regulator and a magnetic controller. Fluid control through the microfluidic channels and chambers is controlled via fluid port selector valves and allows up to eight different solutions. Electrical noise measurements and DNA translocation experiments demonstrate the integrity of the device, with performance comparable to a conventional stand‐alone nanopore setup. However, the microfluidic–nanopore setup is superior in terms of ease of use. To showcase the utility of the device, single molecule detection of a DNA polymerase chain reaction product, after magnetic bead DNA separation, is accomplished on‐chip.
Highly Reliable Liquid Metal–Solid Metal Contacts with a Corrugated Single‐Walled Carbon Nanotube Diffusion Barrier for Stretchable Electronics
Authors: Oh Eunho , Kim Taehoon , Yoon Jaeyoung , Lee Seunghwan , Kim Daesik , Lee Byeongmoon , Byun Junghwan , Cho Hyeon , Ha Jewook , Hong Yongtaek 
Published: October 2018

AbstractLiquid metals (LMs) are a special case of metals that exist in a liquid at room temperature, making them one of the most attractive conductive materials in stretchable electronics. In many cases, however, the LM attacks other metals in contact with the LM through penetration, embrittlement, and alloying. To address these critical issues, there have been efforts to introduce robust barriers, which can preserve the underlying metals without degradation. For example, graphene is employed as a flexible barrier owing to its chemical inertness and impermeability. Nevertheless, this material is difficult to utilize in stretchable electronics because its defects result in inevitable fracture, even at a low strain (< 6%). In addition, it is a challenge to pattern the graphene layer on the point‐of‐interest area in a facile manner. Herein, it is shown that the insertion of single‐walled carbon nanotubes (SWCNTs) at the liquid metal–solid metal interface provides a proper barrier for LM under large deformation conditions. A tangled 1D structure of the SWCNTs formed from a solution process greatly suppresses the crack generation/propagation and maintains conductivity even under large strains, which facilitates the use of SWCNTs as stretchable barriers with long‐term reliability through the introduction of a corrugated structure.
Copper‐Catalyzed Direct and Stereoselective Synthesis of Conjugated Enynes from α‐Allenols
Authors: Sai Masahiro , Matsubara Seijiro 
Published: October 2018

AbstractA novel strategy for the stereoselective synthesis of conjugated enynes directly from α‐allenols has been developed. The reaction proceeds with perfect E‐selectivity and exhibits high functional group compatibility. This catalytic system can also be applied to the stereoselective synthesis of conjugated dienynes and enediynes.magnified image
New formula and conversion factor to compute basic wood density of tree species using a global wood technology database
Authors: Vieilledent Ghislain , Fischer Fabian Jörg , Chave Jérôme , Guibal Daniel , Langbour Patrick , Gérard Jean 
Published: October 2018

Premise of the StudyBasic wood density is an important ecological trait for woody plants. It is used to characterize species performance and fitness in community ecology and to compute tree and forest biomass in carbon cycle studies. While wood density has been historically measured at 12% moisture, it is convenient for ecological purposes to convert this measure to basic wood density, i.e., the ratio of dry mass over green volume. Basic wood density can then be used to compute tree dry biomass from living tree volume.MethodsHere, we derive a new exact formula to compute the basic wood density Db from the density at moisture content w denoted Dw, the fiber saturation point S, and the volumetric shrinkage coefficient R. We estimated a new conversion factor using a global wood technology database where values to use this formula are available for 4022 trees collected in 64 countries (mostly tropical) and representing 872 species.Key ResultsWe show that previous conversion factors used to convert densities at 12% moisture into basic wood densities are inconsistent. Based on theory and data, we found that basic wood density could be inferred from the density at 12% moisture using the following formula: Db = 0.828D12. This value of 0.828 provides basic wood density estimates 4–5% smaller than values inferred from previous conversion factors.ConclusionsThis new conversion factor should be used to derive basic wood densities in global wood density databases. Its use would prevent overestimating global forest carbon stocks and allow predicting better tree species community dynamics from wood density.