bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution of Modic changes in patients with low back pain and its related factors
Authors: Chen Yufeng , Bao Jie , Yan Qi , Wu Cenhao , Yang Huilin , Zou Jun 
Published: October 2019

Abstract

Background
To summarize the clinical distribution of Modic changes in patients with low back pain and explore the related factors.

Methods
A total of 153 patients were enrolled. Gender, age, disk degeneration, herniation, involved segments, lumbar lordosis angle, and endplate concave angle were recorded, respectively. Patients were divided into two or more groups according to a different classification. The relevant factors were studied with a multivariate logistic regression analysis to analyze their correlation.

Results
A total of 35 patients with type I changes, 110 patients with type II changes, and 8 patients with type III changes. In total, 204 disks were found with Modic changes, L1/2 (10 disks), L2/3 (18 disks), L3/4 (17 disks), L4/5 (76 disks), and L5/S1 (81 disks). Type I changes were distributed mainly under the age of 50. Multivariate regression showed that gender, age, disk degeneration, lumbar lordosis, L4/5 segment lordosis angle, and L5 lower endplate concave angle were related with different types of Modic changes. The regression equation Y = 2.410 − 1.361S − 0.633A − 0.654P + 1.106L − 0.990D (Y means type I changes, S means gender, A means age, P means disk degeneration, L means L4/5 segment lordosis angle, and D means L5 upper endplate concave angle). The OR values were S = 0.256, A = 0.531, P = 0.520, L = 3.022, D = 0.372, respectively.

Conclusions
Type II changes are the most common, followed by type I. Modic changes mostly occur in L4/5 and L5/S1; young, male, lower-grade disk degeneration, normal physiological curvature of the lumbar spine, and normal endplate concave angle were associated with type I changes; gender and lumbar curvature were the most relevant factors for different types.
Conservation issues and chemical study of the causes of alteration of a part of the Stave Church in Hopperstad (Norway)
Authors: Lehne Marit , Mantellato Sara , Aguilar Sanchez Asel Maria , Caruso Francesco 
Published: October 2019

Abstract
An unidentified white substance was observed on the exterior parts of the southern side of Hopperstad Stave Church, located in Vik in Sogn and Fjordane (Norway). One of the 28 remaining stave churches in the country, Hopperstad Stave Church was built between 1130 and 1150 and it constitutes an important part of Norwegian cultural heritage. Such a substance was observed for the first time in 2009 and serious concerns about its harmfulness and origin have been raised. A comprehensive study involving non-invasive (portable XRF) and micro-invasive analyses (SEM, ICP-OES, TOC) was undertaken to investigate the physico-chemical nature of this white substance. Tarring, salt migration from the nearby cemetery, atmospheric agents, leakages from the roof, biological infestation, previous treatments with pesticides are among the possible causes of the phenomenon. This work—employing a unique approach in conservation/conservation science—indicates that the white substance is mainly inorganic and crystalline. It was, therefore, possible to exclude some of the possible causes, hence, clarifying some of the conservation issues of the church.
Observed versus predicted fire behavior in an Alaskan black spruce forest ecosystem: an experimental fire case study
Authors: Drury Stacy A. 
Published: October 2019

Abstract

Background
Fire managers tasked with assessing the hazard and risk of wildfire in Alaska, USA, tend to have more confidence in fire behavior prediction modeling systems developed in Canada than similar systems developed in the US. In 1992, Canadian fire behavior systems were adopted for modeling fire hazard and risk in Alaska and are used by fire suppression specialists and fire planners working within the state. However, as new US-based fire behavior modeling tools are developed, Alaskan fire managers are encouraged to adopt the use of US-based systems. Few studies exist in the scientific literature that inform fire managers as to the efficacy of fire behavior modeling tools in Alaska. In this study, I provide information to aid fire managers when tasked with deciding which system for modeling fire behavior is most appropriate for their use. On the Magitchlie Creek Fire in Alaska, I systematically collected fire behavior characteristics within a black spruce (Picea mariana [Mill.] Britton, Sterns & Poggenb.) ecosystem under head fire conditions. I compared my fire behavior observations including flame length, rate of spread, and head fire intensity with fire behavior predictions from the US fire modeling system BehavePlus, and three Canadian systems: RedAPP, CanFIRE, and the Crown Fire Initiation and Spread system (CFIS).

Results
All four modeling systems produced reasonable rate of spread predictions although the Canadian systems provided predictions slightly closer to the observed fire behavior. The Canadian fire behavior prediction modeling systems RedAPP and CanFIRE provided more accurate predictions of head fire intensity and fire type than BehavePlus or CFIS.

Conclusions
The most appropriate fire behavior modeling system for use in Alaskan black spruce ecosystems depends on what type of questions are being asked. For determining the rate of fire movement across a landscape, REDapp, CanFIRE, CFIS, or BehavePlus can all be expected to provide reasonably accurate estimates of rate of spread. If fire managers are interested in using predicted flame length or energy produced for informing decisions such as which firefighting tactics will be successful, or for evaluating the ecological impacts due to burning, then the Canadian fire modeling systems outperformed BehavePlus in this case study.
Extent of disease at first cancer presentation and previous anxiety and depressive symptoms: the HUNT study
Authors: Stewart Robert , Fosså Sophie Dorothea , Hotopf Matthew , Mykletun Arnstein 
Published: October 2019

BackgroundDepressive symptoms are associated with higher cancer mortality, whereas anxiety symptoms are associated with lower than expected risk.AimsThis study aimed to investigate the prospective association between depressive/anxiety symptoms and the extent of disease (EOD) of first cancer at diagnosis.MethodProspective population-based study conducted from the second wave of the Nord-Trøndelag Health (HUNT) study. Of 65 000 residents comprehensively interviewed and examined for health status, 407 received first lifetime cancer diagnoses 1–3 years later, ascertained from the Cancer Registry of Norway, and had EOD recorded. Patients with localised disease or regional/distant spread at cancer diagnosis were analysed for earlier depressive/anxiety symptoms ascertained by the Hospital Anxiety and Depression Scale in HUNT.ResultsBeyond-local EOD was present in 59.8% of those with neither anxiety nor depression, in 76.6% of those with depression alone (odds ratio, 2.20; 1.08–4.49), in 39.3% of those with anxiety alone (odds ratio, 0.44; 0.20–0.96) and in 57.7% of those with both anxiety and depression (odds ratio, 0.92; 0.41–2.06). After adjustment for demographic and health status, and cancer type, these associations were marginally stronger, but no longer statistically significant (odds ratios, 2.26; 0.84–6.11; 0.43; 0.15–1.26; and 1.00; 0.98–1.03, respectively).ConclusionsIn people who develop cancer, beyond-local EOD at diagnosis was more common in people with previous depression and less common in people with previous anxiety; however, independence from confounding factors could not be concluded.
Multidisciplinary Cancer Management of Colorectal Cancer in Tikur Anbessa Specialized Hospital, Ethiopia
Authors: Deressa Biniyam Tefera , Cihoric Nikola , Tefesse Ephrem , Assefa Mathewos , Zemenfes Daniel 
Published: October 2019

PURPOSE Multidisciplinary cancer care is currently considered worldwide as standard for the management of patients with cancer. It improves patient diagnostic and staging accuracy and provides patients the benefit of having physicians of various specialties participating in their treatment plan. The purpose of this study was to describe the profile of patients discussed in the Tikur Anbessa Multidisciplinary Tumor Board (MTB) and the potential benefits brought by multidisciplinary care. METHODS The study involved the retrospective assessment of all patient cases presented to the Tikur Anbessa Hospital colorectal cancers MTB between March 2016 and November 2017. The data were collected from the MTB medical summary documents and were analyzed using SPSS version 20 (SPSS, Chicago, IL). RESULTS Of 147 patients with colorectal cancer, 96 (65%) were men. The median age at presentation was 46 years (range, 17-78 years). The predominant cancer was rectal (n = 101; 69%), followed by colon (n = 24; 16%). Of these, 68 (45%) and 22 (15%) had stage III and IV disease, respectively, on presentation to the MTB. The oncology department presented the majority of the patients for discussion. Most patients had undergone surgery before the MTB discussion but had no proper preoperative clinical staging information. The majority of patients with rectal cancer treated before the MTB discussion had undergone surgery upfront; however, most of the patients who were treatment naive before MTB received neoadjuvant chemoradiotherapy before surgery. CONCLUSION Decisions made by tumor boards are more likely to conform to evidence-based guidelines than are those made by individual clinicians. Therefore, early referral of patients to MTB before any treatment should be encouraged. Finally, other hospitals in Ethiopia should take a lesson from the Tikur Anbessa Hospital colorectal cancers MTB and adopt multidisciplinary cancer management.
Definition and Coordination of Roles and Responsibilities Among Cancer Center Clinic and Research Personnel
Authors: Craddock Lee Simon J. , Reimer Torsten , Garcia Sandra , Williams Erin L. , West Mary , Stuart Tobi , Gerber David E. 
Published: October 2019

PURPOSE: Effective enrollment and treatment of patients in cancer clinical trials require definition and coordination of roles and responsibilities among clinic and research personnel. MATERIALS AND METHODS: We developed a survey that incorporated modified components of the Survey of Physician Attitudes Regarding the Care of Cancer Survivors. Surveys were administered to clinic nursing staff and research personnel at a National Cancer Institute–designated comprehensive cancer center. Results were analyzed using χ2-tests, t tests, and analyses of variance. RESULTS: Surveys were completed by 105 staff members (n = 50 research staff, n = 55 clinic staff; 61% response rate). Research staff were more likely to feel that they had the skills to answer questions, convey information, and provide education for patients on trials (all P < .05). Both clinic and research staff reported receipt of communication about responsibilities in fewer than 30% of cases, although research staff reported provision of such information in more than 60% of cases. Among 20 tasks related to care of patients in trials, no single preferred model of responsibility assignment was selected by the majority of clinic staff for nine tasks (45%) or by research staff for three tasks (15%). Uncertainty about which team coordinates care was reported by three times as many clinic staff as research staff ( P = .01). There was also substantial variation in the preferred model for delivery of care to patients in trials ( P < .05). CONCLUSION: Knowledge, attitudes, and perception of care and responsibilities for patients on clinical trials differ between and among clinic and research personnel. Additional research about how these findings affect efficiency and quality of care on clinical trials is needed.
Optimizing Postprandial Glucose Management in Adults With Insulin-Requiring Diabetes: Report and Recommendations
Authors: Leahy John (Jack) L , Aleppo Grazia , Fonseca Vivian A , Garg Satish K , Hirsch Irl B , McCall Anthony L , McGill Janet B , Polonsky William H 
Published: October 2019

AbstractFaster-acting insulins, new noninsulin drug classes, more flexible insulin-delivery systems, and improved continuous glucose monitoring devices offer unprecedented opportunities to improve postprandial glucose (PPG) management and overall care for adults with insulin-treated diabetes. These developments led the Endocrine Society to convene a working panel of diabetes experts in December 2018 to assess the current state of PPG management, identify innovative ways to improve self-management and quality of life, and align best practices to current and emerging treatment and monitoring options. Drawing on current research and collective clinical experience, we considered the following issues for the ∼200 million adults worldwide with type 1 and insulin-requiring type 2 diabetes: (i) the role of PPG management in reducing the risk of diabetes complications; (ii) barriers preventing effective PPG management; (iii) strategies to reduce PPG excursions and improve patient quality of life; and (iv) education and clinical tools to support endocrinologists in improving PPG management. We concluded that managing PPG to minimize or prevent diabetes-related complications will require elucidating fundamental questions about optimal ways to quantify and clinically assess the metabolic dysregulation and consequences of the abnormal postprandial state in diabetes and recommend research strategies to address these questions. We also identified practical strategies and tools that are already available to reduce barriers to effective PPG management, optimize use of new and emerging clinical tools, and improve patient self-management and quality of life.
From Sanctuary to Safe Space
Authors: Ellison Treva 
Published: October 2019

Abstract
This article focuses on how the trajectories of gay and lesbian police-reform efforts in Los Angeles model a transition from a politics of sanctuary to the production of safe space. The production of safe space is conditioned by the multiplication of discourses of race, gender, and sexuality emblematized by the rise of identity-based neighborhood politics throughout the postwar period, and how these politics interface with the reterritorialization of the welfare state and the advent of community policing. The article historicizes several Stonewall-era gay organizations, showing how activists enacted a politics of sanctuary that helped to decriminalize gay and lesbian identity, and then arguing that this politics of sanctuary was drawn into the production of safe space. This writing invites possibilities for abolitionist organizing by demonstrating the life cycle of law and order that circumscribes urban, identity-based, antiviolence, and neighborhood-based politics.
Sanctuary Squats
Authors: Hung Carla 
Published: October 2019

AbstractThis article details the political contestations of refugee occupiers after they were violently evicted from their home, colloquially called Piazza Indipendenza. Participant observation as a friend of the Eritrean refugees who occupied Piazza Indipendenza during the time of their eviction brought to light the way refugee occupiers both demand rights to subsidized housing and care for each other. Refugees confront the discriminatory distribution of integration resources in Italy by establishing autonomous structures, like housing occupations of abandoned buildings, to both approximate their entitlement to subsidized housing and assert their rights. For many Eritrean refugee occupiers in Rome, it is the Habesha community itself that provides the most reliable form of care, shelter, and protection, such that migrant-occupied housing projects (squats) act as sites of sanctuary. Sanctuary squats act as shelters from which to contest repressive governmental policies.
Freedom to Move, Freedom to Stay, Freedom to Return
Authors: Maira Sunaina 
Published: October 2019

AbstractThis article focuses on the sanctuary movement in the United States and Europe, putting into conversation with one another migrant solidarity activists from different national contexts. This transnational roundtable draws on interviews with activists in the San Francisco Bay Area as well as in the United Kingdom and Switzerland, and on a workshop on sanctuary activism that involved forty activists from the Bay Area, Europe, and Australia. The article explores the meaning of sanctuary in these different locations and the strategies used by activists to create various forms of sanctuary while grappling with its contradictions. It addresses three key themes: (1) the meaning of sanctuary in campaigns that enact the right to freedom of movement across borders; (2) the binary of “good”/deserving versus “bad”/unworthy migrants; and (3) an abolitionist sanctuary model that links border violence to carcerality, neoliberal capitalism, white supremacy, settler colonialism, and fascism.
Compression Garments Reduce Muscle Movement and Activation during Submaximal Running
Authors: BROATCH JAMES R. , BROPHY-WILLIAMS NED , PHILLIPS ELISSA J. , O’BRYAN STEVEN J. , HALSON SHONA L. , BARNES SHANNON , BISHOP DAVID J. 
Published: October 2019

ABSTRACT

Purpose
The purpose of this study was to investigate the effectiveness of sports compression tights in reducing muscle movement and activation during running.

Methods
A total of 27 recreationally active males were recruited across two separate studies. For study 1, 13 participants (mean ± SD = 84.1 ± 9.4 kg, 22 ± 3 yr) completed two 4-min treadmill running bouts (2 min at 12 and 15 km·h−1) under two conditions: a no-compression control (CON1) and compression (COMP). For study 2, 14 participants (77.8 ± 8.4 kg, 27 ± 5 yr) completed four 9-min treadmill running bouts (3 min at 8, 10, and 12 km·h−1) under four conditions: a no-compression control (CON2) and three different commercially available compression tights (2XU, Nike, and Under Armor). Using Vicon 3D motion capture technology, lower limb muscle displacement was investigated in both study 1 (thigh and calf) and study 2 (vastus lateralis + medialis [VAS]; lateral + medial gastrocnemius [GAS]). In addition, study 2 investigated the effects of compression on soft tissue vibrations (root-mean-square of resultant acceleration, RMS A
r), muscle activation (iEMG), and running economy (oxygen consumption, V˙O2) during treadmill running.

Results
Wearing compression during treadmill running reduced thigh and calf muscle displacement as compared with no compression (both studies), which was evident across all running speeds. Compression also reduced RMS A
r and iEMG during treadmill running, but it had no effect on running economy (study 2).

Conclusion
Lower limb compression garments are effective in reducing muscle displacement, soft tissue vibrations, and muscle activation associated with the impact forces experienced during running.
Interventional radiology training: a comparison of 5 English-speaking countries
Authors: Mandal Indrajeet , Minocha Amal , Yeung Jason , Bandula Steve , Rabouhans Jeremy 
Published: October 2019

Objective:
To compare key characteristics of interventional radiology (IR) training in the UK with four other English-speaking countries (USA, Canada, Australia and New Zealand) and summarise requirements for training.

Methods:
Main features examined were career pathway and requirements, examinations required, specific competition for IR and the process of applying for training as an international medical graduate. Data were collected from official governing body publications, literature and personal experience.

Results:
Several differences were highlighted, including length of training (ranging from 6 to 9 years after medical school), length of IR-specific training (ranging from 1 to 3 years) and examinations required (USA and Canada have additional IR-specific examinations). The level of competition is generally high, in all countries.

Conclusions:
With the demand for IR services set to increase over the next few years, it is crucial that more IR specialists are trained to meet this demand. Awareness of training structures in other countries can highlight opportunity and pitfalls, and help ensure the number of highly trained interventional radiologists in the UK continues to grow.
Validation of two-dimensional vertebral body parameters in estimating patient height in elderly patients
Authors: Waduud Mohammed Abdul , Sucharitkul Penelope Poppy Janpen , Drozd Michael , Gupta Ankit , Hammond Christopher , Ashbridge Scott David Julian 
Published: October 2019

Objectives
Standardised comparison of abdominal muscle and adipose tissue is often utilised in morphometric clinical research. Whilst measurements are traditionally standardised against the patient’s height, this may not be always practically feasible. The aim of this study was to investigate the relationship between measurements of the vertebral body and patient height.

Methods
We analysed cross-sectional CT scans. Measurements of the vertebral body area (VBA), anteroposterior vertebral body diameter (APVBD) and lateral vertebral body diameter (LVBD) were made by two independent investigators by manual tracing. Patients were randomly divided into two groups: Group 1 standardisation and Group 2 validation. We compared height and vertebral body parameters from patients in Group 1 and mathematically modelled this relationship. We then utilised the model to predict the height of patients in Group 2 and compared this with their actual height. Observer variability was assessed using Bland–Altman plots and t-tests of differences.

Results
CT scans from 382 patients were analysed. No significant intraobserver or interobserver differences were apparent when measuring vertebral body parameters. We describe models which enable the prediction of the patients’ height using the measured VBA, APVBD and LVBD. No significant differences were observed between the patients predicted and actual heights in the validation group.

Conclusions
We demonstrate an important relationship between measurements of the patient’s height and the vertebral body. This can be utilised in future research when the patient’s height has not been measured.

Advances in knowledge
In the absence of the patient’s height, we demonstrate that two-dimensional vertebral body parameters may be reliably used to standardise morphometric measurements.
Red List of Estonian Fungi – 2019 update
Authors: Saar Irja , Oja Jane , Põldmaa Kadri , Pärtel Kadri , Zettur Irma , Kõljalg Urmas 
Published: October 2019

In 2019 the conservation status of 214 fungal species in Estonia was assessed according to IUCN criteria and an IUCN category was assigned to each taxon. Altogether 94 species were categorized as threatened (CR, EN, VU), 42 least concern (LC), 60 near threatened (NT), three regionally extinct (RE) and six as data deficient (DD). Changes compared to the previous red list and threats to the species are discussed.

Eesti seente Punane nimestik – 2019. aasta uuendus
2019. aastal hinnati 214 seeneliigi ohustatust Eestis kasutades IUCN kategooriaid ja kriteeriume. Hinnatud liikidest kuulus 94 ohustatuse kategooriatesse CR, EN ja VU, 42 hinnati kui soodsas seisundis (LC), 60 ohulähedased (NT), 3 piirkonnas välja surnud (RE) ja 6 puuduliku andmestikuga (DD). Artikkel käsitleb muudatusi võrreldes eelmise punase nimestikuga ja olulisemate seeneliikide ohutegureid.