bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medication-related osteonecrosis of the jaws after tooth extraction in senescent female mice treated with zoledronic acid: microtomographic, histological and immunohistochemical characterization
Authors: Biguetti Claudia Cristina , De Oliva André Hergesel , Healy Kent , Mahmoud Ramez Hassan , Custódio Isabela Do Carmo , Constantino Dulce Helena , Ervolino Edilson , Duarte Marco Antonio Hungaro , Fakhouri Walid D. , Matsumoto Mariza Akemi 
Published: March 2019

AbstractTreatment with cumulative dosages of zoledronic acid (ZA) in elderly patients is a risk factor for the development of medication-related osteonecrosis of the jaws (MRONJ), mainly related to surgical triggers such as tooth extraction. However, animal models for the investigation and understanding of MRONJ pathophysiology in senescent and postmenopausal stages remains to be developed and characterized. The aim of this study was to analyze MRONJ development in senescent female mice treated with cumulative dosages of ZA. For this purpose, twenty 129/Sv female mice, 64 weeks old, were treated with 0.9% saline solution as Control group (n=10), and with ZA at 250µg/Kg (n=10), once a week, starting 4 weeks before the upper right incisor extraction and until the end of the experimental time points (7 days and 21 days). At 7 and 21 days, specimens were harvested for microCT, histological, birefringence and immunohistochemical analysis. Clinically, an incomplete epithelialization was observed in ZA group at 7 days and a delayed bone matrix mineralization and collagen maturation at 7 and 21 days compared to the controls. Controls revealed sockets filled with mature bone at 21 days as observed by microCT and birefringence, while ZA group presented delayed bone deposition at 7 and 21 days, as well increased leukocyte infiltration and blood clot at 7 days, and increased bone sequestrum and empty osteocyte lacunae at 21 days (p<0.05). Also, ZA group presented decreased quantity TGFb+ and Runx-2+ cells at 7 days, and decreased quantity of TRAP+ osteoclasts compared to the control at 21 days (p<0.05). Togheter, these data demonstrate the usefulness of this model to understanding the pathophysiology of MRONJ.
Trait plasticity of intensive pasture species due to growth in mixture across seasons and nutrient addition levels
Authors: Mason Norman W.H. , Lambie Suzanne , Waugh Deanne , Orwin Kate , Carmona Carlos P. , Mudge Paul 
Published: March 2019

AbstractQuestionsHow do the traits of pastoral species respond to growth in mixture, nitrogen addition and season? What are the impacts of trait plasticity on community aggregate trait values?Study siteA large-scale field experiment on intensively managed dairy pastures in New Zealand.MethodsWe measured traits linked to rate of return on investment in leaves – leaf nitrogen content (leaf N) and specific leaf area (SLA) – and biomass investment in leaf area – leaf area ratio (LAR). We collected trait data for 5 pasture species (one grass, two forbs, and two N2-fixing legumes) grown in monoculture or a five-species mixture across three levels of nitrogen (N) addition in four seasons. For each species in each season we tested for significant effects of growth in mixture, N addition, and their interaction. We calculated community-weighted mean (CWM) values in mixture plots using traits collected either from mixtures or monocultures. We tested for significant mixture and N addition effects on CWM, and for significant interactions between mixture and N addition.ResultsSLA and LAR for all non-N2-fixers were significantly higher in spring, summer or autumn, and never significantly lower in mixture than in monoculture. All three non-N2-fixers experienced higher leaf N in mixture during summer, but two species had significantly lower leaf N in either winter or autumn. Mixture effects on CWM values for all three traits were negative in winter and positive in either spring or summer.ConclusionsThe direction of trait plasticity effects on community level trait means was highly seasonally dependent.
Development of a model estimating root length density from root impacts on a soil profile in pearl millet (Pennisetum glaucum(L.) R. Br). Application to measure root system response to water stress in field conditions
Authors: Faye A. , Sine B. , Chopart J.L. , Grondin A. , Lucas M. , Diedhiou A. , Gantet P. , Cournac L. , Min D. , Audebert A. , Kane A. , Laplaze L. 
Published: March 2019

AbstractPearl millet, unlike other cereals, is able to withstand dry and hot conditions and plays an important role for food security in arid and semi-arid areas of Africa and India. However, low soil fertility and drought constrain pearl millet yield. One of the main targets to address these constraints through agricultural practices or breeding is root system architecture. In this study, in order to easily phenotype the root system in field conditions, we developed a model to predict root length density (RLD) of pearl millet plants from root intersection densities (RID) counted on a trench profile in field conditions. We identified root orientation as an important parameter to improve the relationship between RID and RLD. Root orientation was notably found to differ between thick roots (more anisotropic with depth) and fine roots (isotropic at all depths). We used our model to study pearl millet root system response to drought and showed that pearl millet reorients its root growth toward deeper soil layers that retain more water in these conditions. Overall, this model opens ways for the characterization of the impact of environmental factors and management practices on pearl millet root system development.
Identification of the impurity phase in high-purity CeB6 by convergent-beam electron diffraction
Authors: Peng Ding , Nakashima Philip N. H. 
Published: March 2019

The rare earth hexaborides are known for their tendency towards very high crystal perfection. They can be grown into large single crystals of very high purity by inert gas arc floating zone refinement. The authors have found that single-crystal cerium hexaboride grown in this manner contains a significant number of inclusions of an impurity phase that interrupts the otherwise single crystallinity of this prominent cathode material. An iterative approach is used to unequivocally determine the space group and the lattice parameters of the impurity phase based on geometries of convergent-beam electron diffraction (CBED) patterns and the symmetry elements that they possess in their intensity distributions. It is found that the impurity phase has a tetragonal unit cell with space group P4/mbm and lattice parameters a = b = 7.23 ± 0.03 and c = 4.09 ± 0.02 Å. These agree very well with those of a known material, CeB4. Confirmation that this is indeed the identity of the impurity phase is provided by quantitative CBED (QCBED) where the very close match between experimental and calculated CBED patterns has confirmed the atomic structure. Further confirmation is provided by a density functional theory calculation and also by high-angle annular dark-field scanning transmission electron microscopy.
Control and empowerment as an organising paradox: implications for management control systems
Authors: Lewis Rachael L. , Brown David A. , Sutton Nicole C. 
Published: March 2019

PurposeThe purpose of this paper is to reframe the debate about the tension between management control and employee empowerment by drawing on a theory of paradox. Reframing the problem in this way draws attention to the variety of ways in which organisations can attend to both control and empowerment simultaneously.Design/methodology/approachThe authors undertake a conceptual examination of the relationship between empowerment and control using a paradox theory lens. First, the authors bring together two dimensions of empowerment – structural empowerment and psychological empowerment – and combine them to produce three new empowerment “scenarios”: illusory empowerment, obstructed empowerment and authentic empowerment. For each of these three scenarios, the central tenets of paradox theory are applied in order to explain the nature of the paradoxical tension, anticipated behavioural responses and the resulting challenges for ongoing management control.FindingsThe authors find that neither structural nor psychological empowerment alone can account for variation in behavioural responses to management control. The conceptual analysis highlights the interplay of socio-ideological control and systems of accountability in generating psychological empowerment and demonstrates that this does not come at a cost to management control but instead results in a reduction in the scale and scope of ongoing challenges.Originality/valueThis paper contributes a new theoretical perspective on the classic problem of tension between management control and employee empowerment. Rather than positioning control and empowerment either as a managerial choice or dialectic, the authors identify three different ways in which organisations can engage with both paradoxical elements simultaneously.
How many girls are we missing in ASD? An examination from a clinic- and community-based sample
Authors: Barnard-Brak Lucy , Richman David , Almekdash M. Hasan 
Published: March 2019

Purpose
Research has indicated that males diagnosed with autism spectrum disorder (ASD) outnumber females diagnosed with ASD, which has been attributed to a number of potential biological and genetic risk factors. The purpose of this paper is to estimate how many girls may be missing from ASD via a two-study format, comparing two distinct data sets to Centers for Disease Control and Prevention population estimates for sex distribution of males vs females in ASD.

Design/methodology/approach
In Study 1, the authors utilized data from the National Database for Autism Research as a clinic-based sample. In Study 2, the authors utilized data from the National Survey of Children’s Health as a community-based sample.

Findings
The current study estimates that approximately 39 percent more girls should be diagnosed with ASD. The authors estimate that the sex distribution in ASD should be approximately 28 percent female and 72 percent male based upon current practices. Thus, it appears that more females are being identified as potentially having ASD but were not subsequently being diagnosed with ASD as compared to their male counterparts.

Originality/value
These results could suggest that a leaky pipeline in the assessment of girls with ASD may exist along one or more points in the ASD diagnostic process, with one potential point at the level of ASD-specific screening (i.e. the SCQ in Study 1) in the clinic setting and another in the community setting as a whole for universal screening (i.e. NSCH data in Study 2).
Festival attachment: antecedents and effects on place attachment and place loyalty
Authors: Tsaur Sheng-Hshiung , Wang Yao-Chin , Liu Chyong-Ru , Huang Wen-Shiung 
Published: March 2019

PurposeThe purpose of this paper is to propose the mechanism of festival attachment and examine how it serves as a significant predictor of place attachment and place loyalty.Design/methodology/approachThrough on-site survey with convenience sampling, 465 visitors were surveyed at the Pingxi Sky Lantern Festival, which is one of the most famous Taiwanese festivals. Structural equation modeling is used to examine the proposed research model.FindingsEmpirical results of this study reveal that “hedonism” is the most important antecedent for improving festival attachment, followed by novelty seeking, attractions and cultural exploration. Festival attachment exerts positive effects on place attachment, which then increases place loyalty. Moreover, place attachment partially mediates the relationship between festival attachment and place loyalty.Originality/valueBy hosting festivals, festival managers can induce festival attachment in visitors and then transfer the attachment with festivals into the host place. The findings of this study demonstrate the major role of festivals in promoting local tourism.
Changes in subjective wellbeing of prisoners on remand
Authors: Bloem Oscar , Bulten Erik , Verkes Robbert-Jan 
Published: March 2019

Purpose
Low levels of subjective wellbeing in prisoners may relate to mental health problems and difficulties in reintegration after imprisonment. The development of subjective wellbeing during imprisonment is mostly unclear. The purpose of this paper is to explore this development in a longitudinal study in association with mental disorders and socioeconomic factors.

Design/methodology/approach
Subjective wellbeing was assessed via a visual analogue scale and retrieved at admission to remand prison and then again after four and eight weeks. Changes in subjective wellbeing between time-points were analyzed taking into account mental disorders and socioeconomic factors, which were assessed by use of the Mini International Neuropsychiatric Interview – Plus and the Camberwell Assessment of Need – Forensic Version, respectively.

Findings
On average, subjective wellbeing declined directly after remand prison admission, but differences between individuals were found. At remand prison admission, subjective wellbeing significantly improved rather than declined in prisoners with alcohol and substance use disorders, housing problems, unemployment prior to incarceration and in relatively older prisoners. Other related factors did not add significance to this model. In contrast, during remand imprisonment subjective wellbeing displayed an overall increase. For this increase, no predicting factors were found. However, prisoners with an antisocial personality disorder are more at risk of experiencing a decrease in wellbeing during remand imprisonment.

Originality/value
In general, the Dutch prison system appears not to result in a decrease in subjective wellbeing in prisoners suffering from a mental disorder during remand imprisonment.
Comparing health status, disability, and access to care in older and younger inmates in the New South Wales corrections system
Authors: Field Courtney , Archer Vicki 
Published: March 2019

Purpose
The purpose of this paper is to compare the rates of chronic illness, disability and access to care between older and younger inmates who took part in a large epidemiological study in New South Wales, Australia.

Design/methodology/approach
Data are presented from a cross-sectional study based on a sample of inmates from correctional sites in NSW. The inclusion of results here was guided by the literature with regard to their relevance to older people, and older inmates in particular.

Findings
Results indicate that a higher proportion of older inmates suffer a range of chronic illnesses, with prevalence often many times higher than that of younger inmates. Older inmates are more likely to be classified as disabled and have a disability which impacts their mobility. Older inmates also reported accessing medical services in prison more recently than younger inmates and were more likely to have seen both nurses and general practitioners.

Practical implications
Older inmates appear to be considerably more resource intensive than younger inmates. The increasing proportion of inmates who are classified as older thus poses a pressing challenge to those working in the carceral space and, in particular, those responsible for providing healthcare to incarcerated people.

Originality/value
The impact of aging prisoners on resource demand has yet to be effectively measured. This study provides an important first step towards that goal.
Assessments of mental capacity: upholding the rights of the vulnerable or the misleading comfort of pseudo objectivity?
Authors: Rogers Jim , Bright Lucy 
Published: March 2019

PurposeThe purpose of this paper is to present findings from a research project which investigated the approaches of different groups of assessors to the mental capacity assessments which are required to be conducted as part of Deprivation of Liberty Safeguards (DOLS).Design/methodology/approachFour case study vignettes were given to participants. Three groups involved in the DOLS assessment process were interviewed by telephone about the factors that may influence their capacity assessments.FindingsMost assessors did not refer to the required two-stage test of capacity or the “causative nexus” which requires that assessors must make clear that it is the identified “diagnostic” element which is leading to the inability to meet the “functional” requirements of the capacity test. The normative element of capacity assessments is acknowledged by a number of assessors who suggest that judging a person’s ability to “weigh” information, in particular, is a subjective and value-based exercise, which is given pseudo objectivity by the language of the Mental Capacity Act (MCA). A number of elements of good practice were also identified.Research limitations/implicationsIn this exploratory study, participant numbers were small (n=21), and the authors relied on self-report rather than actual observations of practice or audit of completed assessments.Practical implicationsThe findings are of relevance to all of those working in health and social care who undertake assessments of mental capacity, and will be helpful to all of those tasked with designing and delivering training in relation to the MCA 2005. They also have relevance to policy makers in the UK who are involved with reforms to DOLS regulations, and to those in other countries which have legislation similar to the MCA.Originality/valueMuch existing literature exhorts further training around the MCA. The authors suggest that an equally important task is for practitioners to understand and be explicit about the normative elements of the process, and the place of ethics and values alongside the more cognitive and procedural aspects of capacity assessments.
Process and output control in marketing channels: toward understanding their heterogeneous effects
Authors: Brown James R. , Crosno Jody L. 
Published: March 2019

Purpose
Extant research has demonstrated that marketing channel control can produce both positive and negative effects. This paper aims to use meta-analysis to understand potential sources of those heterogeneous effects. This research also identifies areas in need of future research to help deepen the understanding of marketing channel control.

Design/methodology/approach
This study uses meta-analysis to quantitatively review some of the methodological factors that might explain conflicting results uncovered in previous empirical studies.

Findings
The results generally show a positive relationship between process and output control and their studied correlates. They also show that the effects of process and output control vary by the methodological factors used to study them. In particular, the effects of process and output control appears to be stronger in industrial (vs consumer) markets, service (vs goods) industries and in studies conducted in non-Western (vs Western) cultures; and output monitoring measures appear to be more effective than output control measures, yet process monitoring appears to be less effective than process control in marketing channels.

Originality/value
This original meta-analysis review of the literature on organizational control in marketing channels shows that the effects of process and output control vary according to the research context investigated as well as the specific measure of control used. The paper presents an agenda to guide future research on this topic to more fully develop knowledge of organizational control in marketing channels.
Blockchain for business
Authors: George Rohith P. , Peterson Brad L. , Yaros Oliver , Beam David L. , Dibbell Julian M. , Moore Riley C. 
Published: March 2019

Purpose
To introduce blockchain in simple terms for business lawyers to be able to spot the right issues and ask the right questions.

Design/methodology/approach
This article provides an overview of blockchain, identifies two example use cases, and highlights some of the most pressing legal issues, including issues to address in on-chain programming, off-chain agreements and other issues when determining whether to implement a blockchain solution.

Findings
This article concludes that there has been a significant growth in investment and interest in blockchain. Numerous companies across different sectors have developed blockchain proof-of-concepts, with some heading towards production deployments. At this point, commercial blockchain is largely in the pilot or proof-of-concept stage across a wide range of use cases, with payments and supply chain being two of the most promising use cases. This article also identifies possible legal issues associated with blockchain.

Practical implications
Despite the growing interest in blockchain, it is still a novel topic to many business lawyers. It is very important that lawyers are able to identify the right issues and ask the right questions.

Originality/value
Practical guidance from experienced lawyers in the Technology Transactions and Financial Services Regulatory & Enforcement practices.
US SEC report calls for better internal accounting controls for cyber-related threats
Authors: Martin David , Engvall David , Burke Kerry , Hodgkins Gerald , Franker Matthew , Hooper Reid 
Published: March 2019

Purpose
To summarize and explain the US Securities and Exchange Commission’s (Commission) recent report of investigation cautioning public companies to consider cyber-related threats when designing and implementing internal accounting controls.

Design/methodology/approach
Explains that the Commission’s report arose out of a Commission enforcement investigation into the internal accounting controls of nine unidentified public companies that were victims of email scams, explains that the Commission issued the report to emphasize that cybersecurity remains a high priority for the Commission and the report should serve as a reminder that all public companies need to consider cyber-related threats when devising and maintaining internal accounting controls and provides practical considerations for public companies to consider in light of the Commission’s report.

Findings
Public companies should assume that the Commission is actively monitoring all areas related to cybersecurity, including corporate disclosures of cyber-related incidents and also whether companies have established policies, procedures, and internal controls in place to ensure cyber-related incidents are prevented. Given that assumption, public companies should take prompt steps to assess and, if appropriate, improve internal accounting controls, disclosure controls, and cyber-related policies and procedures to address the risk of cyber-related incidents.

Originality/value
Practical guidance from experienced securities lawyers.