bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Static and Dynamic Stretching on Force Sense, Dynamic Flexibility and Reaction Time of Children
Authors: Chatzopoulos Dimitris , Doganis Georgios , Lykesas Georgios , Koutlianos Nikolaos , Galazoulas Christos , Bassa Eleni 
Published: August 2019

Background:
Traditionally, stretching protocols are basic components of warm-up aiming to improve performance and reduce injuries. However, the literature suggests that different stretching protocols during warm-up may have diverse effects on performance.

Objective:
The purpose of this study was to compare the acute effects of three different stretching protocols on force sense, dynamic flexibility, reaction time and movement time.

Methods:
The study included twenty-five participants who were TaeKwonDo young male players (age = 11.78 ± 1.66 years.). All the participants performed one of the following protocols on different days: (a) 5 min jogging followed by 3 min Static Stretching (SS), (b) 5 min jogging followed by 3 min Dynamic Stretching (DS), and (c) 5 min jogging followed by 3 min of rest (NS). After the protocols, the participants performed the following measurements: (a) force-matching test at 20% maximal isometric voluntary contraction (force sense), (b) active straight leg raise test (dynamic flexibility) and (c) reaction and movement time test.

Results:
Repeated measures analysis of variance revealed no significant main effects on force sense. Furthermore, SS performed significantly better in dynamic flexibility in comparison to NS, and DS performed significantly better in terms of dynamic flexibility and movement time compared to SS.

Conclusion:
According to the results of the study, it seems that force sense is not affected by either SS or DS protocols (30 sec duration per muscle group). Moreover, it seems that DS in the warm-up is more appropriate than SS for activities requiring dynamic flexibility and movement time.
Regulation and Clinical Investigation of Medical Device in the European Union
Authors: Manita  , Deep Aakash , Vikram  , Rana Avtar C. , Sharma Prabodh C. 
Published: August 2019

Background::Medical devices are the machine, tool, instrument, apparatus, implant, calibrator in vitro, software, the similar or related object intended for use by the manufacturer alone or in combination becoming increasingly important in the healthcare sector as these are used to diagnosis, control, prevention or treatment of an illness. Safety of the world population is the highest priority in order to launch new medical devices for the treatment and diagnostic of several diseases. New innovation in industries and regulations work together to provide devices for different world market and to improve quality and safety of exiting devices in the market. The main key for devices is to classify the determination of actual regulatory pathway which ensures the safety standards and other regulatory requirements in a specific country. We perform clinical trials for medical device which are quite different from the clinical trials performed for drug analysis. For any high-risk devices, the new EU law states that the manufacturer has to prepare a complete summary for their evidence. The clinical trials regulation provides more transparency on clinical trials data. Complete transparency is required for the maximum possibility of informed decisions in order to use new medical devices.Objective::The current manuscript will provide the information regarding the regulatory framework for the approval of medical devices and clinical investigation of medical device in European Union and comparison of approval process of medical device in USA, EU and India. The aim of this paper is to provide an overview of the most suitable and emerging requirements that manufacturers need for introducing their medical devices in the market in compliance with the MDR regulations.Conclusion::The proposal for a modified regulation of medical devices aims to ensure more robust clinical data in support of the CE marking applications of the medical device. The clinical investigation requirements will be mandatory, and there will be an obligation to demonstrate the clinical benefits of the device and provide a rigorous equivalence test if the assessment is based on comparison devices. The new European legislation should require the premarket demonstration of clinical efficacy and safety, using a randomized controlled trial if possible, and a transparent clinical review, preferably centralized.
Impact of Perinatal Different Intrauterine Environments on Child Growth and Development: Planning and Baseline Data for a Cohort Study
Authors: Werlang Isabel Cristina Ribas , Bernardi Juliana Rombaldi , Nunes Marina , Marcelino Thiago Beltram , Bosa Vera Lucia , Michalowski Mariana Bohns , da Silva Clécio Homrich , Goldani Marcelo Zubaran 
Published: August 2019

Background
Several studies have shown that exposure of the fetus and newborn to prenatal and perinatal events, respectively, may influence the health outcomes of the child throughout their life cycle.

Objective
This study aimed to increase the knowledge on the impact of different intrauterine environments on child growth and development, as we know that pregnancy and early years are a window of opportunity for health promotion and prevention interventions of diseases.

Methods
The recruitment occurred 24 to 48 hours after delivery and involved mothers and their newborns in 2 public hospitals in Porto Alegre, Brazil, from December 2011 to January 2016. The mothers-newborns dyads were allocated to 5 groups: diabetes mellitus, mothers with a clinical diagnosis of diabetes; systemic arterial hypertension (SAH), mothers with a clinical diagnosis of systematic arterial hypertensive disease during pregnancy; maternal smoking, mothers who smoked at any moment of gestation; small for gestational age (SGA), mothers with SGA newborns because of intrauterine growth restriction; and control, mothers without the clinical characteristics previously mentioned. Several protocols and anthropometric measurements were applied in the interviews at immediate postpartum and 7 and 15 days and 1, 3, and 6 months after birth. For this study, we analyzed only data collected during postpartum interviews. The statistical analyses were performed using Pearson chi-square test, Mann-Whitney test, or Kruskal-Wallis test with Dunn post hoc. The significance level was set at 5%. The Hospital Ethics and Research Committees approved the study.

Results
Of the 485 eligible mothers-newborns dyads, 400 agreed to participate (82.5%, 400/485). As expected, newborns from the SGA group had significantly lower birth weight, smaller stature, and lower cephalic perimeter (P<.001). This group also had the highest percentage of primiparous women in comparison with other groups (P=.005) except for control. Mothers from the SAH group had the highest mean age, the highest percentage of cesarean sections, and presented greater gestational weight gain.

Conclusions
In this study, we describe the planning and structure for the systematic follow-up of mother-newborn dyads in the first 6 months after birth, considering the important demographic and epidemiological transition scenario in Brazil. The results of this prospective longitudinal study may provide a better understanding of the causal mechanisms involved in health and life course disease related to different adverse intrauterine environments.
Implementing a Digital Tool to Support Shared Care Planning in Community-Based Mental Health Services: Qualitative Evaluation
Authors: Pithara Christalla , Farr Michelle , Sullivan Sarah A , Edwards Hannah B , Hall William , Gadd Caroline , Walker Julian , Hebden Nick , Horwood Jeremy 
Published: August 2019

Background
Mental health services aim to provide recovery-focused care and facilitate coproduced care planning. In practice, mental health providers can find supporting individualized coproduced care with service users difficult while balancing administrative and performance demands. To help meet this aim and using principles of coproduction, an innovative mobile digital care pathway tool (CPT) was developed to be used on a tablet computer and piloted in the West of England.

Objective
The aim of this study was to examine mental health care providers’ views of and experiences with the CPT during the pilot implementation phase and identify factors influencing its implementation.

Methods
A total of 20 in-depth telephone interviews were conducted with providers participating in the pilot and managers in the host organization. Interviews were audio recorded, transcribed, anonymized, and thematically analyzed guided by the Consolidated Framework for Implementation Research.

Results
The tool was thought to facilitate coproduced recovery-focused care planning, a policy and organizational as well as professional priority. Internet connectivity issues, system interoperability, and access to service users’ health records affected use of the tool during mobile working. The organization’s resources, such as information technology (IT) infrastructure and staff time and IT culture, influenced implementation. Participants’ levels of use of the tool were dependent on knowledge of the tool and self-efficacy; perceived service-user needs and characteristics; and perceptions of impact on the therapeutic relationship. Training and preparation time influenced participants’ confidence in using the tool.

Conclusions
Findings highlight the importance of congruence between staff, organization, and external policy priorities and digital technologies in aiding intervention engagement, and the need for ongoing training and support of those intended to use the technology during and after the end of implementation interventions.
Telemonitoring of Crohn’s Disease and Ulcerative Colitis (TECCU): Cost-Effectiveness Analysis
Authors: Del Hoyo Javier , Nos Pilar , Bastida Guillermo , Faubel Raquel , Muñoz Diana , Garrido-Marín Alejandro , Valero-Pérez Elena , Bejar-Serrano Sergio , Aguas Mariam 
Published: August 2019

Background
Although electronic health interventions are considered safe and efficient, evidence regarding the cost-effectiveness of telemonitoring in inflammatory bowel disease is lacking.

Objective
We aimed to evaluate the cost-effectiveness and cost-utility of the Telemonitorización de la Enfermedad de Crohn y Colitis Ulcerosa (Telemonitoring of Crohn’s Disease and Ulcerative Colitis [TECCU]) Web platform (G_TECCU intervention group) for telemonitoring complex inflammatory bowel disease, compared with standard care (G_control) and nurse-assisted telephone care (G_NT intervention group).

Methods
We analyzed cost-effectiveness from a societal perspective by comparing the 3 follow-up methods used in a previous 24-week randomized controlled trial, conducted at a tertiary university hospital in Spain. Patients with inflammatory bowel disease who initiated immunosuppressants or biologic agents, or both, to control inflammatory activity were recruited consecutively. Data on the effects on disease activity (using clinical indexes) and quality-adjusted life-years (using the EuroQol 5 dimensions questionnaire) were collected. We calculated the costs of health care, equipment, and patients’ productivity and social activity impairment. We compared the mean costs per patient, utilities, and bootstrapped differences.

Results
We included 63 patients (21 patients per group). TECCU saved €1005 (US $1100) per additional patient in remission compared with G_control (95% CI €–13,518 to 3137; US $–14,798 to 3434), with a 79.96% probability of being more effective at lower costs. Compared with G_NT, TECCU saved €2250 (US $2463) per additional patient in remission (95% CI €–15,363 to 11,086; US $–16,817 to 12,135), and G_NT saved €538 (US $589) compared with G_control (95% CI €–6475 to 5303; US $–7088 to 5805). G_TECCU and G_NT showed an 84% and 67% probability, respectively, of producing a cost saving per additional quality-adjusted life-year (QALY) compared with G_control, considering those simulations that involved negative incremental QALYs as well.

Conclusions
There is a high probability that the TECCU Web platform is more cost-effective than standard and telephone care in the short term. Further research considering larger cohorts and longer time horizons is required.

Trial Registration
ClinicalTrials.gov NCT02943538; https://clinicaltrials.gov/ct2/show/NCT02943538 (http://www. webcitation.org/746CRRtDN)
O comum urbano em debate: dos comuns na cidade à cidade como comum? | Urban commons in debate: from the commons in the city to the city as a common?
Authors: Tonucci Filho João Bosco Moura , Cruz Mariana De Moura 
Published: August 2019

Em diferentes cidades ao redor do mundo, a ideia do comum urbano tem sido invocada por movimentos, pesquisadores e até por formuladores de política pública para reivindicar e proteger contra privatizações recursos e bens urbanos que poderiam ser mais amplamente compartilhados entre os habitantes. O objetivo deste artigo é discutir a literatura mais recente que versa sobre o comum urbano, abarcando os estudos que abordam os recursos comuns na cidade até aqueles que tratam a própria cidade (e a vida urbana) como comum. Inicialmente, é contextualizado o surgimento recente dessa literatura e, depois, são rastreados seus principais debates e perspectivas teóricas subjacentes. Em seguida, discute-se como os recursos e espaços comuns na cidade vêm sendo tratados e estudados pelas diferentes abordagens. Por fim, debate-se como a ideia da própria cidade como comum tem recebido atenção de diferentes teóricos, apontando os avanços e limitações dessas abordagens para pensar a cidade além do público e do privado.
Oral Health Status of Hospitalized Patients With Type 2 Diabetes
Authors: Simon Lisa E. , Karhade Deepti Shroff , Tobey Matthew L. 
Published: August 2019

Background
Diabetes is associated with poor oral health, as well as reduced access to dental care. A large percentage of patients hospitalized in the United States carry a diagnosis of diabetes; however, the oral health status of patients with diabetes who are hospitalized is unknown.

Methods
All patients meeting inclusion criteria on the general medicine service of a tertiary care hospital were invited to participate. Subjects were asked about their access to dental care and perceptions of their oral health. A dental hygienist conducted examinations, including decayed, missing, and filled teeth (DMFT) and periodontal screening and recording (PSR) indices on a subset of subjects.

Results
The 105 subjects had a mean age of 69 ± 12 years and a median A1C of 7.5 ± 2.1%. Rates of comorbidity and polypharmacy were high. The mean number of DMFT was 23.0 ± 7.2, with 10.1 ± 7.2 missing teeth. Forty- four percent of subjects had a removable prosthesis. Sixty-eight percent had a PSR index ≥4 in at least one sextant, indicating moderate periodontal disease.

Conclusion
Rates of missing teeth, removable prostheses, and periodonal inflammation were high among hospitalized patients with diabetes, but patients did not perceive their oral health to be poor. Health care providers should be aware of the oral health risks of patients with diabetes during hospitalization, and dentists should consider screening patients with diabetes for recent hospitalization.
Prevalence and molecular characterization of Beta-lactamase resistance gene in multidrug resistance bacteria, Proteus spp.
Authors: S. Salih Sabiha , J. Mohammed Shno , M Noori Imad , MA Mohammed Lana , A. Hama Soor Taib 
Published: August 2019

Existing of drug resistance bacteria in meat is a series of health concern and beta-lactamase is responsible to generate multi drug resistances in bacteria. Meat is a source of delivering food born pathogen bacteria including Proteus species. Recently Proteus bacteria developed drug resistance against many antimicrobial drugs and it causes difficulty in patient’s treatment. Hence its important to indicate the rate of Proteus species, P. mirabilis and P. Vulgaris, in the meat of different animals and to find the prevalence of b-lactamase resistance genes (blaTEM-1, blaCMY, blaCMY2, blaShv, blaOXA, and blaCTX) in Proteus species. Molecular identification of Proteus bacteria was confirmed by PCR amplification of part of 16S rRNA using Proteus specific set of primers. 70 meat samples (cattle, sheep, chicken, turkey, goat, and fish) were collected in local meat shops in the center of Sulaimani city. 29 (41.4%) samples were positive to Proteus species and 22 (75.87%) isolates were P. mirabilis and seven (24.13%) were P. vulgaris based on conventional biochemical tests. The drug sensitivity test was performed for all isolates using a disk diffusion assay (Kirby Bauer test). The multidrug resistance was found in all isolates and the most common drug resistance phenotype were against tetracycline, rifampin, and doxycycline, while the imepenem, tobramycin, and meropenem remain more effective against the bacteria. Resistance genes, blaTEM-1, and blaShv were found in five isolates (17.2%) of Proteus. Three isolates (10.3%) were positive to blaTEM-1 resistance gene and two isolates (6.8%) were positive to blaShv. All resistance genes recorded in this study were recovered in P. mirabilis and none of them was reported in p. vulgaris. None of the isolates was positive to beta-lactamase genes, blaCMY, blaCMY2, blaOXA, and blaCTX.
Stephenean Love Sonnet
Authors: Gill Stephen 
Published: August 2019

About the author:
Multiple award winning self-exiled poet Stephen Gill has authored more than twenty-five books, including novels, literary criticism, and collections of poems. He is the subject of doctoral dissertations, and research papers. Twelve books have been released by scholars and more are to be released on his works. He writes love sonnets within 90 to 100 words. (Sites: stephengill.ca and stephengillcriticism.info )
Les oiseaux
Authors: Kothari Kokila 
Published: August 2019

Regardez les oiseaux
Comme le soleil efface les nuages
Énergique dans le matin
Pas au courant de l’âge
Regardez les oiseaux

Leurs chansons aussi douces que le miel
A la bouche,
Danser à l’oreille,
Étirant leurs ailes
Volant au destin.
Regardez les oiseaux…
Sobre a linguagem nas propostas de ensino de Religião | About language in the proposals of teaching religion
Authors: Thomaz de Almeida Leandro 
Published: August 2019

Fé e política são duas instâncias que não caminham de maneira mutuamente independente. Uma das evidências dessa afirmação se vê nas discussões relativas ao ensino de Religião na escola pública. Como essa questão não é recente, o presente artigo apresenta um panorama cronologicamente abrangente das leis que regulamentaram o ensino religioso nas escolas públicas, com destaque para a contemporaneidade. A ênfase é dada à linguagem que enforma as políticas públicas, bem como à que é utilizada em materiais didáticos sobre ensino de Religião. A partir disso, apresenta-se uma discussão sobre concepções recorrentes a respeito de linguagem, sobre possíveis sentidos dos termos presentes na legislação e sobre a relação entre linguagem, Religião e espaço público. O estudo termina com uma série de propostas de reflexão sobre o assunto em perspectiva crítica, com as quais se procura contemplar um tema que receberá ainda desdobramentos em um futuro próximo.
A New Biomarker in Acute-Decompensated Heart Failure. Preliminary Study
Authors: Ababei Mădălina , Câmpeanu Alexandru , Nistorescu Diana , Zaharia Ondin , Portelli Paul , Nanea Tiberiu 
Published: August 2019

Abstract

Background. It is well known that the NT-proBNP in obese subjects is much lower than in normal weight subjects, making difficult to interpret it. In current practice the patients are frequently obese. In these conditions, a new biomarker, not influenced by weight, could be useful in acute-decompensated heart failure (ADHF).

Aim. To determine CA-125 changes in obese and normal weight patients with ADHF.

Method. The study group included 110 patients (mean age 72±10 years, 63% men) with ADHF caused by ischemic cardiomyopathy. The subjects were clinically, ecocardiographically and biologically (NT-proBNP, CA-125) evaluated.

Results. The mean BMI was 27.6±5.8 kg/m2 and 35 (33%) subjects were obese. CA-125 at admission was 53±33 U/mL and decreased at discharge to 34±17 U/mL, without any difference between males and females.
There was a significant difference between NT-proBNP at admission in obese versus normoponderal patients (3207±1432 pg/mL versus 4457±2737 pg/mL (p=0.02)), which was maintained at discharge (1711±816 pg/mL versus 2674±1475 pg/mL (p=0.03)).
In the same time, the CA-125 did not show statistically significant differences between obese and normoponderal subjects at admission (56±29 U/mL versus 51±20 U/mL (p=0.63)) and discharge (36±20 U/mL versus 33±16 U/mL (p=0.56)).

Conclusions. CA-125 could be an useful biomarker in monitoring the obese patients with ADHF, better than NT-proBNP.
Groove Pancreatitis - Cause of Recurrent Pancreatitis
Authors: Crișu Georgiana , Grigore Monica , Balaban V. , Zoican Andreea , Ciochina Marina , Atanasiu V. , Gaman Laura , Stoian Irina , Costache Raluca , Ioniţă-Radu Florentina , Jinga Mariana 
Published: August 2019

Abstract

Background. Groove pancreatitis or paraduodenal pancreatitis represents a rare type of pancreatitis, and can be classified into cystic dystrophy of the duodenal wall in heterotopic pancreas, paraduodenal cyst or myoadenomatosis.

Case presentation. We present a case of a 58 year old man, drinker and smoker who was admitted in the Department of Gastroenterology for abdominal pain, weight loss and nausea. From his history we have noticed frequent presentations of recurrent acute pancreatitis in the last two years. Laboratory tests have revealed cholestasis, high value of lipase and high value of amylase, with normal value of CA 19.9. The magnetic resonance from the last two years showed the same appearances: a large and edematous head of pancreas, a thickening of the wall of adjacent duodenum and an inhomogeneous area with cystic transformation in the head of the pancreas. We performed endoscopic ultrasound with fine needle aspiration. The histopathological result showed only inflammatory cells. We have established the diagnosis of groove pancreatitis.

Conclusion. Groove pancreatitis represents a rare condition, with an incidence of 0.4%-14% on biopsies. Endoscopic ultrasound is the best method for diagnosis, it could evaluate also the duodenal wall.
Articulação entre ensino, pesquisa e extensão
Authors: Feitosa Raphael Alves , Dias Ana Maria Iório 
Published: August 2019

Este trabalho utiliza a perspectiva das Associações de Companheiros de Ofício aplicada à formação profissional específica e docente para investigar as contribuições do Programa de Educação Tutorial (PET) para uma concepção articulada entre teoria e prática na área de Biologia. Através de um Estudo de Caso com integrantes de um grupo PET de uma universidade federal nordestina, no qual se utiliza análise de documentos e entrevistas, notou-se que os partícipes percebem que as ações desenvolvidas, de forma articulada são importantes para sua formação como futuros docentes de Biologia. Tais ações buscam integrar ensino, pesquisa e extensão, característica dessa política pública; entretanto, carece de articulação com a formação docente, seja para a Educação Básica, seja para a Educação Superior.