bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiological and clinical profile of Korean travelers receiving international medical repatriation
Authors: Kim Jiena , Choi Hyo Jeong , Kim Ho Jung 
Published: September 2019

Abstract
The aim of this study was to investigate the experiences of medical transportation of Korean travelers who suffered accidents abroad and then transferred home by our aeromedical team.
We collected demographic and clinical data on patients injured while traveling abroad from January 2013 to July 2017. Descriptive analyses based on 4 different transportation methods and transport time since hospitalization were performed.
A total of 33 patients were repatriated during the study period. Of these, 28 (84.8%) were trauma cases with pedestrian injuries being the most common (11 cases; 39.3%). Twenty patients were repatriated by flight-stretchers, 6 by flight-prestige, 2 by ship, and 5 by air ambulance. The air ambulance was the most expensive (average 61,124 US Dollars) mode of transportation (P = .001) and the ship took the longest time (14 hours) to transport patients back to Korea from regions with similar distance (P = .0023).
We experienced medical repatriation of 33 seriously injured Korean travelers back to South Korea. Transfer time should be an important considering factor and directly contacting and communicating with the specialized staff of foreign hospitals could also be very important to reduce unnecessary overseas hospital stay and cost incidence.
Bochdalek hernia with Diamond-Blackfan anemia associated with RPS19 gene mutation
Authors: Yoo Ye Seul , Lee Na Hee , Choi Young Bae 
Published: September 2019

Abstract

Rationale:
Diamond-Blackfan anemia (DBA) is a rare inherited marrow disorder, characterized by erythrocyte aplasia and is associated with congenital anomalies and a susceptibility to cancer. Although congenital abnormalities have been observed in ∼50% of DBA patients, the occurrence of an associated congenital diaphragmatic hernia (CDH) has rarely been reported.

Patient concerns:
A 19-month-old male child was referred to our pediatric hematology-oncology outpatient clinic with anemic appearance. He presented to us with recurrent anemia, short stature, and developmental delay.

Diagnosis:
On bone marrow examination, only erythropoietic cells were markedly decreased in number, whereas other cell lines were unaffected. An abdominal computed tomography scan revealed a Bochdalek type of CDH. A genetic analysis revealed heterozygous mutation of RPS19; therefore, he was diagnosed as having DBA with CDH.

Interventions:
The patient received an initial packed red blood cell transfusion, followed by an administration of oral prednisone.

Outcomes:
The patient is maintained on oral prednisone administered at a dose of 0.3 mg/kg every alternate day and has since a hemoglobin level of >9.0 g/dL without further RBC transfusions.

Lessons:
We learned that a Bochdalek type of CDH can manifest in a DBA patient with RPS19 gene mutation. Therefore, patients diagnosed with the latter disorder should also be screened for an early detection of potential CDHs.
The relationship among occupational irradiation, DNA methylation status, and oxidative damage in interventional physicians
Authors: Chen Bin , Dai Qi , Zhang Qun , Yan Peng , Wang Aihong , Qu Linyan , Jin Yinhua , Zhang Dandan 
Published: September 2019

Abstract
Ionizing radiation can induce deoxyribonucleic acid (DNA) methylation pattern change, and ionizing radiation-induced oxidative damage may also affect DNA methylation status. However, the influence of low-dose ionizing radiation, such as occupational radiation exposure, on DNA methylation is still controversial.
By investigating the relationship between occupational radiation exposure and DNA methylation changes, we evaluated whether radiation-induced oxidative damage was related to DNA methylation alterations and then determined the relationship among occupational radiation level, DNA methylation status, and oxidative damage in interventional physicians.
The study population included 117 interventional physicians and 117 controls. We measured global methylation levels of peripheral blood leukocyte DNA and expression level of DNA methyltransferase (Dnmts) and homocysteine (Hcy) in serum to assess the DNA methylation status of the body. We measured 8-hydroxy-2′-deoxyguanosine (8-OHDG) and 4-hydroxynonenal (4-HNE) levels as indices of oxidative damage. Relevance analysis between multiple indices can reflect the relationship among occupational radiation exposure, DNA methylation changes, and oxidative damage in interventional physicians.
The expression levels of Dnmts, 4-HNE, and 8-OHDG in interventional physicians were higher than those in controls, while there was no statistical difference in total DNA methylation rate and expression of Hcy between interventional physicians and controls. Total cumulative personal dose equivalent in interventional physicians was positively correlated with the expression levels of Dnmts, 8-OHDG, and 4-HNE. The expression levels of 8-OHDG in interventional physicians were negatively correlated with global DNA methylation levels and positively correlated with the expression levels of Hcy.
Occupational radiation exposure of interventional physicians has a certain effect on the expression of related enzymes in the process of DNA methylation, while ionizing radiation-induced oxidative damage also has a certain effect on DNA methylation. However, there was no evidence that dose burden of occupational exposure was associated to changes of DNA methylation status of interventional physicians, since it is rather unclear which differences are observed among the effects produced by radiation exposure and oxidative damage.
Catastrophic health expenditure and impoverishment for type 2 diabetes mellitus patients in a multiethnic province in China using a Blinder–Oaxaca decomposition
Authors: Sun Xian , Liabsuetrakul Tippawan , Xie Xiaomin , Liu Ping 
Published: September 2019

Abstract
This study aimed to compare the catastrophic health expenditure (CHE) and impoverishment of type 2 diabetes mellitus (T2DM) patients between 2 ethnic groups and explore the contribution of associated factors to ethnic differences in CHE and impoverishment in Ningxia Hui Autonomous Region, China.
A cross-sectional study was conducted in 2 public hospitals from October 2016 to June 2017. Data were collected by interviewing eligible Hui and Han T2DM inpatients and reviewing the hospital electronic records. Both CHE and impoverishment were measured by headcount and gap. The contributions of associated factors to ethnic differences were analyzed by the Blinder–Oaxaca decomposition technique.
Both the CHE and impoverishment of Hui patients before and after reimbursement were significantly higher than those of Han patients. The ethnic differences in CHE and impoverishment headcount after reimbursement were 11.9% and 9.8%, respectively. The different distributions of associated factors between Hui and Han patients contributed to 60.5% and 35.7% of ethnic differences in CHE and impoverishment, respectively. Household income, occupation, and region were significant contributing factors.
Hui T2DM patients suffered greater CHE and impoverishment than Han patients regardless of reimbursements from health insurance. Differences in socioeconomic status between Hui and Han patients were the main factors behind the ethnic differences.
Krishnan's Comprehensive Classification for Distraction Osteogenesis of Maxilla and Mandible
Authors: Harikrishnan Pandurangan 
Published: September 2019

Abstract
Distraction osteogenesis technique has gained popularity and has been established as a successful procedure in the management of cranio-maxillofacial deformities for more than 2 decades. Varieties of distractor designs were evolved for the procedures in the maxilla and mandible. Various distraction parameters are clinically important as planned in each case. Inspite of distraction osteogenesis as a well-accepted procedure, currently there is no single classification available for the distraction procedure in maxilla and mandible taking into consideration all the relevant parameters. A simple and user-friendly classification was designed with coding all the relevant parameters. A retrospective data collection from distracted case records were used to validate the classification. A survey from maxillofacial surgeons in a regional meeting was also carried out. The validation and the survey showed that the new classification is comprehensive, simple, easy to use and beneficial for communication, data storage, research, coding, and billing purposes.
Mattress Suture Technique for Caudal Septum Dislocations in Open and Endonasal Septoplasty: Which Approach is Better?
Authors: Dikici Oğuzhan , Bayar Muluk Nuray 
Published: September 2019

Objectives:
Various techniques have been described to correct caudal septum dislocations but the issue has not been resolved conclusively. This study aimed to describe a suture technique that can be used to correct and stabilize the caudal septum on the maxillary spine and also to evaluate the effects on patientsymptoms.

Methods:
Fifty-two patients with caudal septal dislocation were included in this study. Nineteen of the patients underwent open septoplasty and 33 patients underwent endonasal septoplasty. The caudal cartilage septums were fixed to the maxillary spine with horizontal mattress suturing in all patients. The patient followed up between 3 and 24th month. The modified “NOSE” survey was used to assess surgical outcome in all patients. The degree of septal correction was also classified.

Results:
Complete correction was achieved in the postoperative period in 96% of the patients. The status was near complete correction in 2 (3.8%) of the patients. But in these 2 patients, degree of caudal septal dislocation was corrected from severe to moderate after surgery and the fixation suture side is correct and stable. Postoperative modified NOSE survey scores were lower than the preoperative scores in all open and endonasal septoplasty groups (P <0.05). NOSE 2 (nasal blockage or obstruction) and NOSE 4 (trouble sleeping) scores were higher in patients with higher follow-up duration in open septoplasty group.

Conclusion:
Suturing technique is quite suitable for caudal septum dislocations and can easily be used in open and endonasal septoplasty. This suture reduces postoperative NOSE scores and the patients are satisfied with the results of the surgery. The septal stability may decrease in open septoplasty group with the longer post-operative duration. However, wide exposure can be ensured with an open septorhinoplasty approach. We concluded that it will be better to use endonasal septoplasty in appropriate cases and suture with nonabsorbable sutures.
Primary Lash Ptosis
Authors: Nemet Arie Y. 
Published: September 2019

Introduction:
Lash ptosis is often an overlooked sign that may coexist with congenital and acquired blepharoptosis. This is a report of case series of patients presented in an oculoplastic clinic with visual field loss associated with lash ptosis. On examination, the primary pathology was attributed to lash ptosis dehiscence.

Methods:
All patients underwent anterior lamellar repositioning and were followed for an average of 15 (10–24) months.

Results:
All patients had resolution of visual field loss and heaviness of eyelids.

Conclusions:
Lash ptosis is associated with abnormalities such as floppy eyelid syndrome. However it may be a primary condition, with no background eyelid pathology and no external explanation for the eyelash ptosis. The condition might result from anatomical changes in the orbicularis oculi, Riolan's muscle, and tarsal plate. Patients in this series complained of upper lid visual field restriction. Anterior lamellar repositioning resulted in complete resolution of complaints. Additional studies are needed to learn about the pathophysiology of this entity.
Single-Port Laparoscopic Hepatectomy for Liver Tumor: Operative Steps (With Video)
Authors: Pan Yangxun , Chen Jinbin , Chen Jiancong , Xu Li , Zhou Zhongguo , Chen Minshan , Zhang Yaojun 
Published: September 2019

Background:
The single-port laparoscopic technique has been widely applied in abdominal surgery. We introduce a single-port laparoscopic hepatectomy for liver tumor in a single center.

Materials and Methods:
This study included 37 patients who underwent single-port laparoscopic liver resection for liver tumor in the segments II, III, IV, and V between October 2017 and November 2018. Their perioperative course and operative techniques were retrospectively evaluated.

Results:
All patients underwent single-port laparoscopic hepatectomy for liver tumor. None of the cases was converted to open surgery. The median procedure duration was 100 minutes (39 to 240 min), and the median blood loss volume was 50 mL (30 to 300 mL). No postoperative complications >3 grades were observed during the perioperative period. The median postoperative hospital stay was 4 days (3 to 7 d).

Conclusions:
Single-port laparoscopic hepatectomy is a safe, feasible, and minimal incision, especially for tumors in the left lobe.
A Supervised, Symmetry-Driven, GUI Toolkit for Mouse Brain Stack Registration and Plane Assignment
Authors: Cicconet Marcelo , Hochbaum Daniel R. 
Published: September 2019

AbstractImmunostaining of brain slices is a ubiquitous technique used throughout neuroscience for the purposes of understanding the anatomical and molecular characteristics of brain circuits. Yet the variety of distortions introduced, and the manual nature of the preparation, hinder the use of the generated images from being rigorously quantified; instead most registration of brain slices is done laboriously by hand. Existing automated registration methods rarely make use of geometric shape information. When registering anterior-posterior brain slices, for example, small errors between consecutive planes accumulate, causing the symmetry axis of a plane to drift away from its starting position as depth increases. Furthermore, planes with imaging artifacts – e.g. one half of the slice is missing – can cause large errors, which are difficult to fix by changing global parameters. In this work we describe a method in which we register a set of consecutive brain slices enforcing all slices to have a vertical axis of symmetry, and then pair these slices optimally to planes from the Allen Mouse Brain Atlas via Dynamic Programming. The pipeline offers multiple human-in-the-loop opportunities, allowing users to fix algorithmic errors in various stages, including symmetry detection and pairwise assignment, via custom graphical interfaces. This pipeline enables large-scale analysis of brain slices, allowing this common technique to be used to generate quantitative datasets.
Insilico analysis of structural and functional impact of SNPs in Pleckstrin
Authors: Pradhan Arpit Kumar , Jainarayanan Ashwin , Nithishwer M. A. , Ghosh Shyamasree 
Published: September 2019

AbstractPleckstrin (PLEK) gene has been associated with a variety of disorders including autoimmune, inflammatory diseases and cancer. Mutation in this gene has been reported to be associated with autoimmune celiac disease (CD), increased atrophy in multiple sclerosis (MS), obstructive sleep apnea (OSA), abdominal aortic aneurysms, over expression in inflammatory disorders including periodontis, risk for ependymoma relapse, bladder cancer, melanoma, lung, and colorectal cancer revealing the importance of study of the PLEK. PLEK gene has been reported from other animals and therefore we have studied the molecular evolution of the PLEK gene by insilico approaches. Single nucleotide polymorphisms (SNPs), in humans have been reported to cause potential structure-function alteration in proteins. In this study we have tried to understand by insilico approaches the (i) molecular evolution of PLEK and (ii) the impact of potentially deleterious single non-synonymous SNPs (nsSNPs) on the structure and function of Pleckstrin protein. We report for the first time using molecular dynamic simulation (MDS), the impact of SNPrs17035364 and rs3816281 on the structural alterations of Pleckstrin with implications in altering its biological function which may find importance as diagnostic markers.
Three-dimensional stability analysis of robotic machining process
Authors: He Feng-Xia , Dai Li , Chen Qisen , Liu Yu , Luo Zhong 
Published: September 2019

Purpose
Since robot’s structural stiffness is usually less than 1 N/µm, mode coupling chatter occurs frequently during robotic milling process, and chatter frequency is close to the natural frequency of the robot itself. Chatter not only affects the surface quality but also damages the robot and reduces the positioning accuracy. Therefore, it is necessary to predict chatter in robotic machining process.

Design/methodology/approach
A three-dimensional dynamic model for robot’s spatial milling plane is established, and a corresponding stability criterion is obtained. First, the cutting force in milling plane is transformed into the coordinate system of the robot principal stiffness direction based on homogeneous transformation matrix. Then the three-dimensional stability criterion under milling process can be obtained by using system stability analysis. Furthermore, the circle diagram of mode coupling chatter stability is drawn. Each feeding direction’s stability under the two processing forms, referred as spindle vertical milling and spindle horizontal milling, is analyzed.

Findings
The experimental results verify that the three-dimensional stability criterion can avoid chatter by selecting machining feed direction in stable area.

Originality/value
This paper established a three-dimensional dynamic model in robot’s spatial milling plane and proposed a three-dimensional stability criterion according to the Routh criterion. The work is also expected to be an efficient tool in the development of robotic milling technology.
A PSO based investigation of research fields of researchers
Authors: Ghosh Goldina , Akki C.B. , Kasturi Nivedita 
Published: September 2019

Purpose
The purpose of this study is data generated from any social networking sites may provide some hidden knowledge on a particular domain. Based on this concept the previous paper had proved that social connectivity enhancement takes place through triadic closure and embeddedness in terms of social network graph-theoretic approach. Further, the work was justified by genetic algorithm (GA) where observation showed how interdisciplinary work can occur because of crossover, and therefore, different groups of researchers could be identified. Further enhancement of the work has been focused on in this paper.

Design/methodology/approach
In continuation with the previous work, this paper detects other possible fields related to “high graded researchers” who can share the information with the other group of researchers (“imminent high graded” and “new researchers”) using particle swarm optimization (PSO) technique.

Findings
While exploitation was done using GA in the previous work, exploration is done in the current work based on PSO using the same grade score value to the objective function. Both the velocity and direction of high graded researchers in this extended work could be derived, which was not possible using GA.

Originality/value
This could help the next two levels of researchers (“imminent high graded researchers” and “new researchers”) in expanding their research fields in line with the fields of high graded researchers.
The evolution of the public sphere
Authors: Blanco José J. 
Published: September 2019

PurposeThe purpose of this study is to rethink the issue of publicity from a cross-cultural and evolutionary perspective.Design/methodology/approachAssuming that there is a dominant paradigm in the studies of the public sphere centered on Habermas’ ideas, media theory (and especially Luhmann who is considered as a media theorist) is selected as a new context that provides different concepts, ideas, language games and metaphors that allow the re-foundation of the study of publicity.FindingsPublicity as a social structure emerges – and acquires different forms during history – out of the complex dynamics resulting from the interaction between success media, such as power, and different kinds of dissemination media.Originality/valueA research into the forms of publicity not only promotes awareness of the ubiquity of the phenomenon across cultural evolution, but also offers tools to make new discoveries and systematize what is already known about the subject and its ramifications.
Surviving sixth form: a story of mental health in adolescence
Authors: Morley Carys J. 
Published: September 2019

Purpose
The purpose of this paper is to share experiences of attending sixth form with mental health difficulties and provide tips to young people for coping. Its aim is to encourage empathy and understanding of young people suffering with mental illness. It is the second in a series of three papers exploring mental health at different stages of education.

Design/methodology/approach
A narrative, first-person approach is taken.

Findings
Advice and reflections for young people with mental health difficulties are provided.

Originality/value
The paper is one person’s experiences and is therefore unique. It contributes a voice to the much-needed discussion on teenagers and mental health, and promotes an understanding of mental health to both teenagers who maybe experiencing difficulties and those who know such teenagers.
Do the most successful migrants emulate natives in well‐being? The compound effect of geographical and social mobility
Authors: Zhao Yizhang 
Published: September 2019

AbstractA growing body of research has been focusing on the well‐being consequences of migration, yet most of this has overlooked the fact that many migrants experience intragenerational social mobility alongside geographical mobility. Without accounting for the effect of social mobility in working life, the impact of geographical mobility on well‐being cannot be clearly examined. This paper focuses on the most successful migrants, who have started from the bottom and have achieved upward social mobility in the course of their careers, and compares their well‐being with that of native non‐migrants who have experienced a similar intragenerational social mobility trajectory. The analysis is based on a recent national survey in China, which has a representative sample for both the overall population and migrants. Findings show that migrants, whether from an urban or rural origin, have better incomes but significantly lower levels of well‐being than natives, even with a similar career advancement trajectory and the same destination class position. Further exploration shows that the well‐being disadvantage of migrants is mainly due to institutional and sociocultural barriers, rather than to reward differentials in the labour market. This may have a wider implication for migrants across national borders.