bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-functional interconnectedness as an enabler of customer value
Authors: Seno João Paulo , Pimenta Marcio Lopes , Hilletofth Per , Eriksson David 
Published: January 2019

Purpose
The purpose of this study is to analyze the processes of interconnectedness in cross-functional relationships involved in customer value enabling.

Design/methodology/approach
In total, 20 in-depth interviews were conducted in three Brazilian companies from different industries. The critical incident technique was used for data collection and analysis. Content analysis was used to characterize the critical incidents within functional area networks.

Findings
Six main critical incidents were identified within the studied relationships: process, urgency, lack of trust, capacity and demand imbalance, motivation and challenge. The results show situations in which the collaborative behavior of the actors generates customer value facilitation.

Research limitations/implications
The firms studied are small and medium, located in an emerging economy and are resource-constrained. Further research could be performed in organizations in other countries with different sizes and resources. Future studies could also include customers within the analyzed functional networks to evaluate value-in-use behavior.

Practical implications
Process, as a critical incident, may be composed of several elements that could affect the processes of value creation. Moreover, the adjustment between production capacity and demand should focus on avoiding propagation of functional problems through the processes. This focus may facilitate spontaneous community behavior and customer knowledge renewal.

Originality/value
This paper generates new qualitative bases to characterize the interconnectedness within functional networks within the perspective of relationship marketing. The study of the internal functions and processes revealed several particularities that are not evidenced in the extant literature, which is concentrated in relationships among companies. The quality of the relationship among the members of a functional network may affect the effectiveness of the promises of customer value, more specifically in value enabling.
The role of cognitive proximity on supply chain collaboration for radical and incremental innovation: a study of a transition economy
Authors: Nguyen Mai Anh Thi , Lei Hui , Vu Khoa Dinh , Le Phong Ba 
Published: January 2019

PurposeThe purpose of this paper is to investigate the role of cognitive proximity on supply chain collaboration and how it relates to radical and incremental innovation.Design/methodology/approachThe paper is based on quantitative approach to analyze the data of 218 firms in a developing and transition economy. The proposal model is tested with exploratory factor analysis (EFA), confirmatory factor analysis (CFA) and structural equation modeling (SEM).FindingsThe authors’ findings show that cognitive proximity facilitates decision synchronization and incentive alignment in the supply chain. Furthermore, the authors’ results indicate that information sharing and decision synchronization are determinants of radical innovation while incentive alignment is a determinant of incremental innovation.Research limitations/implicationsThis study was cross-sectional, so the authors could not consider the control variable such as sectors or firms’ size. It is hard to control the specific features of cognitive proximity in one single industry when using cross-sectional data. In future investigations, it may be possible to use a different dimension of proximity to explain the implementation of collaboration for innovation.Originality/valueThis study attempted to explore the role of cognitive proximity on supply chain implementation process in the context of a transition economy. Moreover, the authors’ findings provide the clearer understanding of the relationship between collaboration and innovation.
Enhancing sustainable performance through job characteristics via workplace spirituality
Authors: Iqbal Qaisar , Ahmad Noor Hazlina , Ahmad Basheer 
Published: January 2019

PurposeThis paper aims to provide empirical evidence of the associations between perceived job characteristics and workplace spirituality with environmental sustainability within the domain of small- and medium-sized enterprises. This study aims to investigate the influence of perceived job characteristics (job identity, task significance and task variety) on environmental sustainability through workplace spirituality.Design/methodology/approachData are collected from 400 small and medium enterprises (SME) employees working in New Delhi, India, and Islamabad, Pakistan. Response rate in this study is 58 per cent. Structural equation modeling has been used to analyze the data through SmartPLS 3.0 and SPSS version 24.FindingsThe results indicate that perceived job characteristics have significant positive influence over workplace spirituality. It is concluded that workplace spirituality also significantly mediates the relationship between perceived job characteristics and environmental sustainability.Research limitations/implicationsIn the present study, perceived job characteristics have been evaluated to improve environmental sustainability in SMEs from Pakistan and India. Therefore, before generalization in the context of other countries can be made, the results obtained may need some modifications.Practical implicationsThe research concerns the understanding of various job characteristics and environmental sustainability from the viewpoint of employees in SMEs at imparting perceived job characteristics as important factors to meet challenges relevant to environmental sustainability in the dynamic market.Social implicationsThere is anecdotal evidence claiming the pivotal role of job characteristics and workplace spirituality toward the recognition of sustainability in the progressive dynamic market. The results of this study represent the effectiveness of perceived job characteristics for accomplishing social objectives through workplace spirituality.Originality/valueThis study contributes to the field by bringing together the concepts of workplace spirituality with perceived job characteristics and environmental sustainability in the context of Pakistani and Indian SMEs.
Social capital and health care access among the older adults in Bangladesh
Authors: Islam Md. Shahidul 
Published: January 2019

Purpose
The purpose of this paper is to investigate the association between social capital (SC) and health care access problem among the older people in Bangladesh.

Design/methodology/approach
This study applied a random sampling method to select 310 older adults (all aged 60 years) in Bangladesh. Exploratory factor analysis was employed to extract SC dimensions. Logistic regression was applied to measure the association of SC dimensions and access.

Findings
The logistic regression result shows that with a one-unit increase in social network, norms of reciprocity, and civic participation, health care access problem will be decreased by OR= 0.732 (95% CI =0.529–1.014); OR=0.641 (95% CI = 0.447–0.919); and OR=0.748 (95% CI = 0.556–1.006) units. Respondents who have economic hardship were 3.211 (OR=3.211, CI = 0.84–5.59) times more likely to say that they had health care access problem compared with who had no economic hardship.

Research limitations/implications
The study showed that the lower level of SC and presence of economic hardship increased the probability to health care access problem among the older people. Improving SC may be helpful in reducing health care access problem. However, economic hardship reductions are also important to reduce the health care access problem. Improving SC and reducing economic hardship thus should be implemented at the same time.

Practical implications
The study showed that low SC and economic hardship increased the probability to health care access problem. Improving SC may be helpful in reducing health inequity. However, economic hardship reductions also important to health care access. Therefore, improving SC and reducing economic hardship should be implemented at the same time.

Originality/value
This study has a great policy importance in regard to reducing health care access problem among the older adult in Bangladesh as SC has a potential to bring about a concomitant improvement in the condition of the health care access.
Relationship between stromal cells and tumor spread through air spaces in lung adenocarcinoma
Authors: Qiu Xie , Chen Donglai , Liu Yangyang , Duan Shanzhou , Zhang Fuquan , Zhang Yongsheng , Li Feng , Chen Chang , Chen Yongbing 
Published: January 2019

BackgroundThe mechanism underlying tumor spread through air spaces (STAS) has not been well studied. We investigated the role of tumor stromal cells in the pathogenesis of STAS from a pathological perspective and evaluated the prognostic significance of tumor stromal cells and STAS in postoperative patients with lung adenocarcinoma.MethodsWe retrospectively analyzed 208 postsurgical patients with stage I–IIIA lung adenocarcinoma. The presence of STAS was evaluated by hematoxylin and eosin staining. The expression of α‐smooth muscle actin (SMA)‐positive cancer‐associated fibroblasts (CAFs) and CD204‐positive tumor‐associated macrophages (TAMs) was analyzed by immunohistochemistry. A logistic regression model was applied to confirm the predictive factors of STAS. Survival analysis was performed to evaluate the effect of α‐SMA‐positive CAFs, CD204‐positive TAMs, and STAS on prognosis. A nomogram was generated to evaluate the prognosis of postoperative patients.ResultsLogistic regression suggested that the expression of α‐SMA‐positive CAFs (P < 0.001) and the number of CD204‐positive TAMs (P < 0.001) were related to the presence of STAS. The multivariate Cox proportional hazards model suggested that STAS (P = 0.004), α‐SMA‐positive CAFs (P < 0.001), and CD204‐positive TAMs (P < 0.001) were independent risk factors for prognosis. Harrell's c‐indexes for overall and recurrence‐free survival prediction based on nomograms were 0.84 (95% confidence interval 0.76–0.91) and 0.82 (95% confidence interval 0.76–0.89), respectively.ConclusionsThe presence of STAS was associated with high expression of α‐SMA and CD204 in lung adenocarcinoma. Nomograms including STAS and stromal cells as variables are recommended as practical models to evaluate the prognosis of lung adenocarcinoma patients.
Clinical significance and biological role of cancer‐derived Type I collagen in lung and esophageal cancers
Authors: Fang Shuo , Dai Yongdong , Mei Yan , Yang Mingming , Hu Liang , Yang Hong , Guan Xininyuan , Li Jiangchao 
Published: January 2019

BackgroundExtracellular matrix (ECM) is remodeled during carcinogenesis. An abundant constituent of ECM is collagen. Type I collagen is secreted by fibroblasts, is important for tumor growth and epithelial‐mesenchymal transition, and may also be secreted by cancer cells. However, the role and function of cancer‐derived Type I collagen in the tumor microenvironment remains unclear.MethodsWe used immunohistochemistry and Western blot to detect Type I collagen expression in non‐small cell lung cancer (NSCLC) and esophageal squamous cell carcinoma (ESCC) cell lines, respectively. We assessed the migration and adhesion capability of these cells in vivo by inhibiting Type I collagen in tumors. Relevant data were extracted from a large cohort study of The Cancer Genome Atlas to analyze messenger RNA levels. Protein expression of Type I collagen was further determined in tumor tissues of patients using tissue microarray.ResultsCancer cell lines secreted Type I collagen. The molecular weight of cancer‐derived Type I collagen was different from that secreted by cancer‐associated fibroblasts and normal fibroblasts. Expression levels of COL1A1 and COL1A2 (subtypes of Type I collagen) messenger RNA in NSCLC and ESCC tumors were higher than in normal tissues, but were not associated with tumor node metastasis stages. Low expression of Type I collagen was significantly associated with poor overall survival and cancer cell differentiation.ConclusionNSCLC and ESCC cells could produce Type I collagen endogenously, revealing the potential functions of Type I collagen in cancer development. Cancer‐derived Type I collagen was associated with overall survival and cancer cell differentiation.
New models of lipopolysaccharide‐induced implantation loss reveal insights into the inflammatory response
Authors: Moustafa Sarah , Joseph Dana N. , Taylor Robert N. , Whirledge Shannon 
Published: January 2019

ProblemChronic endometritis, inflammation of the uterizzvvne lining caused by common gram‐negative bacterial strains or mycoplasma, has been associated with unexplained implantation failure and infertility. However, limited models of bacteria‐induced implantation loss exist to study the molecular changes that occur in vivo. The goal of this study was to provide a new resource to study the process of bacteria‐induced inflammation and implantation loss utilizing common experimental models: C57Bl/6 mice and primary human endometrial stromal cells.Method of studyPrior to implantation, mated C57Bl/6 females were administered vehicle (saline) or gram‐negative bacterial lipopolysaccharide (LPS) at a range of concentrations by intraperitoneal injection. Implantation sites were counted, and uteri were harvested to evaluate the molecular changes that accompany LPS‐mediated implantation loss. Primary human endometrial stromal cells were decidualized in vitro in the presence and absence of LPS. Total RNA and conditioned media were harvested to evaluate the expression of known decidualization‐associated genes and various cytokines and chemokines.ResultsLipopolysaccharide treatment resulted in fewer implantation sites in mice, decreased expression of decidualization‐associated genes, and altered expression and release of cytokines and chemokines. Immunohistological analysis of the uterus from LPS‐exposed mice demonstrated increased apoptosis and decreased proliferation during decidualization.ConclusionLipopolysaccharide exposure disrupted implantation and decidualization in mice and human endometrial stromal cells. This model could be used to study the pathophysiology of implantation failure in patients with chronic endometritis or to test potential therapeutic interventions.
Multi‐modal prehabilitation: addressing the why, when, what, how, who and where next?
Authors: Scheede‐Bergdahl C. , Minnella E. M. , Carli F. 
Published: January 2019

SummaryJust as there is growing interest in enhancing recovery after surgery, prehabilitation is becoming a recognised means of preparing the patient physically for their operation and/or subsequent treatment. Exercise training is an important stimulus for improving low cardiovascular fitness and preserving lean muscle mass, which are critical factors in how well the patient recovers from surgery. Despite the usual focus on exercise, it is important to recognise the contribution of nutritional optimisation and psychological wellbeing for both the adherence and the response to the physical training stimulus. This article reviews the importance of a multi‐modal approach to prehabilitation in order to maximise its impact in the pre‐surgical period, as well as critical future steps in its development and integration in the healthcare system.
Pre‐operative nutrition and the elective surgical patient: why, how and what?
Authors: Gillis C. , Wischmeyer P. E. 
Published: January 2019

SummaryPre‐operative nutrition therapy is increasingly recognised as an essential component of surgical care. The present review has been formatted using Simon Sinek's Golden Circle approach to explain ‘why’ avoiding pre‐operative malnutrition and supporting protein anabolism are important goals for the elective surgical patient, ‘how’ peri‐operative malnutrition develops leading in part to a requirement for pre‐operative anabolic preparation, and ‘what’ can be done to avoid pre‐operative malnutrition and support anabolism for optimal recovery.
Psychological factors, prehabilitation and surgical outcomes: evidence and future directions
Authors: Levett D. Z. H. , Grimmett C. 
Published: January 2019

SummaryThe pre‐operative optimisation of comorbidities is increasingly recognised as an important element of the pre‐operative pathway. These efforts have primarily focused on physical comorbidities such as anaemia and the optimisation of exercise and nutrition. However, there is a growing recognition of the importance of psychological morbidity. Increasingly, evidence suggests that psychological factors have an impact on surgical outcomes in both the short and long term. Pre‐operative anxiety, depression and low self‐efficacy are consistently associated with worse physiological surgical outcomes and postoperative quality of life. This has led to the emergence of psychological prehabilitation and the trimodal approach to prehabilitation, incorporating psychological intervention as well as exercise and nutritional optimisation. However, there is currently insufficient evidence to be sure that pre‐operative psychological interventions are of benefit, or which interventions are most effective, because their impact has been mixed. There is an urgent need for high quality, contemporaneous prospective trials with baseline psychological evaluation, well‐described interventions and agreement on the most appropriate psychological, quality of life and physiological outcomes measures.
Peri‐operative optimisation of elderly and frail patients: a narrative review
Authors: Chan S. P. , Ip K. Y. , Irwin M. G. 
Published: January 2019

SummaryWith increasing life expectancy and technological advancement, provision of anaesthesia for elderly patients has become a significant part of the overall case‐load. These patients are unique, not only because they are older with more propensity for comorbidity but a decline in physiological reserve and cognitive function invariably accompanies ageing; this can substantially impact peri‐operative outcome and quality of recovery. Furthermore, it is not only morbidity and mortality that matters; quality of life is also especially relevant in this vulnerable population. Comprehensive geriatric assessment is a patient‐centred and multidisciplinary approach to peri‐operative care. The assessment of frailty has a central role in the pre‐operative evaluation of the elderly. Other essential domains include optimisation of nutritional status, assessment of baseline cognitive function and proper approach to patient counselling and the decision‐making process. Anaesthetists should be proactive in multidisciplinary care to achieve better outcomes; they are integral to the process.
The weekend effect in status epilepticus: a national cohort study
Authors: Goulden R. , Whitehouse T. , Murphy N. , Hayton T. , Khan Z. , Shyamsundar M. , Gao‐Smith F. , Snelson C. , Bion J. , Veenith T. 
Published: January 2019

SummaryHigher mortality following admission to hospital at the weekend has been reported for several conditions. It is unclear whether this variation is due to differences in patients or their care. Status epilepticus mandates hospital admission and usually critical care: its study might provide new insights into the nature of any weekend effect. We studied 20,922 adults admitted to UK critical care with status epilepticus from 2010 to 2015. We used multiple logistic regression to evaluate the association between weekend admission and in‐hospital mortality, comparing university hospitals with other hospitals. There were 2462 in‐hospital deaths (12%). There was no difference in mortality after weekend admission to university hospitals, adjusted odds ratio (95%CI) 0.99 (0.84–1.16), p = 0.89. Mortality was less after weekend admission than after admissions Monday to Friday in hospitals not associated with a university, adjusted odds ratio (95%CI) 0.74 (0.64–0.87), p = 0.0001. There is no evidence that adults admitted to UK critical care at the weekend in status epilepticus are more likely to die than similar patients admitted during the week.
Fannie Lou Hamer's Freedom Farms and Black Agrarian Geographies
Authors: McCutcheon Priscilla 
Published: January 2019

AbstractThis paper examines Fannie Lou Hamer's Freedom Farms, a 1969 farming cooperative in Sunflower County, Mississippi. Specifically, this paper interrogates how Hamer's identity as a Black southern woman influences her formulation and daily activities at Freedom Farms. Theoretically, this paper situates Hamer as an expert agrarian labourer and knowledge producer who exists within a history of Black women who have always been utilised for their agrarian knowledge, but given little credit. Hamer's knowledge is a part of her body. This paper argues that Freedom Farms is a Black radical geography operating at three scales: the body, the farm and the southern agrarian landscape. This paper utilises Hamer's speeches, interviews and other archival documents to understand Hamer's efforts. Hamer's agrarian landscape is wrought with pain, but also the insistence in the economic opportunity that exists for Black people in agrarian spaces.
Endoscopy‐assisted laparoscopic submucosal dissection for a duodenal epithelial tumor
Authors: Miyazaki Yasuhiro , Takiguchi Shuji , Kurokawa Yukinori , Takahashi Tsuyoshi , Fukuda Yasunari , Yamasaki Makoto , Makino Tomoki , Tanaka Koji , Motoori Masaaki , Kimura Yutaka , Nakajima Kiyokazu , Mori Masaki , Doki Yuichiro 
Published: January 2019

AbstractWe present the case of a 46‐year‐old obese woman with a 3.5‐cm adenoma in the descending part of the duodenum who was treated with a totally laparoscopic approach. The preoperative examination revealed a pedunculated superficial tumor on the side of pancreas from the inferior duodenal angulus to 5 cm proximal to the papilla that was associated with massive blood flow. We chose not to perform endoscopic submucosal dissection, pancreaticoduodenectomy, or transduodenal tumor excision with laparotomy for this obese patient because of the poor exposure, risk of bleeding, and substantial invasiveness. We performed endoscopy‐assisted laparoscopic submucosal dissection as a novel laparoscopic‐endoscopic cooperative surgical approach in this patient. This surgery was surgically and oncologically safe.
Impact of Botryosphaeria, Diplodia and Neofusicoccum species on two Eucalyptus species and a hybrid: From pathogenicity to physiological performance
Authors: Barradas Carla , Pinto Glória , Correia Barbara , Jesus Cláudia , Alves Artur 
Published: January 2019

AbstractSpecies of Botryosphaeriaceae are associated with canker and dieback of Eucalyptus spp. worldwide, but little is known about their effect on the host physiology. The aim of this study was to evaluate the impact of Botryosphaeriaceae isolates from nine species in three genera (Botryosphaeria, Diplodia and Neofusicoccum), previously isolated from eucalypts, on three different Eucalyptus hosts (seedlings of E. nitens, cuttings of E. globulusand of E. globulus× E. cypellocarpa). An approach combining standard pathogenicity trials with evaluation of plant morpho‐physiological parameters was used. The size of the lesions produced revealed differences in fungal aggressiveness and host susceptibility. Isolates of Neofusicoccum kwambonambienseand Diplodia corticolawere the most aggressive, while Botryosphaeria dothidea and Diplodia seriataisolates were the least aggressive. In general, hybrid E. globulus× E. cypellocarpa plants developed smaller lesions, followed by E. nitens and E. globulus. Eucalyptus nitensplants showed minimal modifications on the morpho‐physiological profile when infected, although more severe symptoms and mortality were observed. This is probably due to a more variable genetic background of the plants. However, in general, no direct association between putative fungal aggressiveness and plant physiological disorders could be found. Results suggested that under optimal growth conditions plants manage to cope with pathogen attack and maintain their physiological performance.