bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiology of Dermatophytes and Non Dermatophyte Molds among Patients Attending Rank Higher Specialized Dermatology Clinic, Addis Ababa, Ethiopia
Authors: Araya Shambel , Tesfaye Betelhem , Fente Desalegn 
Published: July 2019

Abstract
Background

Dermatophytes are keratinophilic fungi that infect keratinized tissuescausing diseases known as dermatophytosis. Dermatophytosis is common worldwide and continues to increase.

Objective

This study was undertaken to determine the prevalence of dermatophytes and the spectrum of fungal agents in patients attending Rank higher clinic.

Methods

a cross sectional study has been conducted, in which 318 Samples from 318 suspected patient was collected from hair, nail and skin. A portion of each sample was examined microscopically and the remaining portion of each sample was cultured onto plates of Sabouraud’s dextrose agar containing chloramphenicol with and without cycloheximide. Dermatophyte isolates were identified by studying macroscopic and microscopic characteristics of their colonies.

Result

Of 318 samples, fungi were detected in 133 (54.4%) by direct wet mount while 148/315(46.5%) of them were culture positive. From these 72/148(46.8%) were dermatophytes. Among dermatophyte isolates T. tonsurans 29/72(40.2%) was the most common cause of infection. Tinea capitis was the predominant clinical manifestation accounting for 170/315(53.4%) of the cases. Patients with age group 1-14 years were more affected.T. tonsurans was the most common pathogen in tinea capitis, whereas T. mentagrophytes was the most common pathogen in tinea corporis.

Conclusion

In this study the prevalence of dermatophytes were higher in tinea capitis 46/72(63.8%) and T.tonsurans29/72(40%) was the dominant isolated dermatophyte. Recovery of large number of dermatophytes and non-dermatophyte fungi in our study showed that Non-dermatophyte fungi are emerging as important causes of dermatophytosis warranting further intensive epidemiological studies which have public health significance are needed.
Effects of insulin on the reversal of myocardial contractility after bupivacaine-induced cardiac asystole in vitro
Authors: Kim Hyun Joo , Jung Ja Rang , III Carl Lynch , Park Wyun Kon 
Published: July 2019

Abstract
Background: Insulin-glucose treatment effectively reverses severe bupivacaine (BPV)-induced myocardial depression or cardiovascular collapse in in vivo. However, the mechanisms for the recovery are poorly defined.
Methods: Using the guinea pig myocardium, cumulative concentration-responses on contractile forces for insulin or insulin combined with 33 mM glucose (insulin/glucose) were measured. After achieving asystole by 500 µM BPV, different concentrations of insulin or insulin/glucose were applied to determine the recovery of stimulated contractile responses and contractions in either recirculating or non-recirculating (washout) condition. Because we did not observe any recovery from asystole with insulin treatment in the recirculating condition, further experiments were performed whether intermittent contractile responses (conduction block) could be reversed by insulin. In the washout condition, after achieving asystole, the muscles were washed with the Tyrode solution containing insulin or insulin/glucose for 60 minutes. After achieving asystole, BPV concentrations in the Tyrode solution in the presence or absence of insulin for 60 minutes were measured.
Results: There were similar concentration-dependent decreases in contractility in both the insulin and insulin/glucose groups. Neither insulin nor insulin/glucose restored the stimulated contractile responses from conduction disturbance or asystole induced by BPV in the continued presence of BPV. In the BPV-washout condition, while superfusion with a control (plain Tyrode) solution for 60 minutes after achieving asystole by BPV restored contractility to approximately 60% of the baseline, time-dependent complete recovery was observed in the insulin- and insulin/glucose-treated groups. At each time period from asystole to 60 minutes, the BPV concentrations in the insulin-treated group were slightly lower than those in the control group.
Conclusions: Neither insulin nor insulin/glucose treatment does not rescue Na+ channel function to reverse BPV-induced cardiac conduction block or asystole regardless of improved cardiac performance, possibly due to improved myocardial energetics in isolated in vitro animal myocardium model. These findings suggest that treatment with insulin or insulin/glucose is desirable for metabolic energy supply to the myocardium in cases of BPV-induced cardiac collapse. However, considering the importance of decreased BPV concentrations in cardiac tissues, insulin or insulin/glucose may not achieve satisfactory outcomes.
Host genetic factors associated with hepatitis B virus infection and progression to chronic disease: A systematic review and Meta analysis
Authors: Kafeero Hussein Mukasa , Ndagire Dorothy Ndagire , Nanyingi Hasifah Nanyingi , Sendagire Hakim Sendagire 
Published: July 2019

Abstract
Abstract
Back ground
Contradicting results from many laboratories on the role of genetic factors in the susceptibility/resistance to hepatitis B infection have been reported. In this review we examined 27 published full research articles and assessed the role of Th1/Th2 cytokine promoter and vitamin D receptor gene polymorphisms. We summarized the available data on the relationship between the gene polymorphisms and susceptibility/resistance to hepatitis B virus infection together with likely disease evolution to come up with candidate single nucleotide polymorphisms implicated in the disease state with the population.
Method
The study was done in tandem with the PRISMA standards and the Cochran’s Q test, I2 statistics for heterogeneity and the Odds ratio were calculated using a commercially available soft ware called MedCalcs (http://www.medcalc.org). A random effects model was used to pool the odds ratio for heterogeneities ≥50% or else a fixed effects model was used. All analyses were done at 95% Confidence Interval and a P<0.05 was considered statistically significant.
Results
We found that IL-10-592C/A genotype AA (P=0.017, OR=0.752, 95%CI=0.595 to 0.950) and TNF-α-238G/A genotype AA+ AG (P<0.001, OR=0.407, 95%CI=0.005 to 30.1) were significantly associated with reduced risk of hepatitis B infection by the random effects model. TNF-α-238G/A genotype GG had the risk of chronic infection (OR=3.587, 95% CI= 0.127 to 101.176) under the random effect model. Most of the other SNPs had borderline risk of HBV infection (OR 0.6 to 1.12) with a few cases of high risk, IL-10-1082A/G genotype AA (OR=1.608, 95%CI=0.861 to 3.003) and reduced risk, IL-10-1082A/G genotype AG (OR=0.485, 95% CI=0.232 to 1.014)
Conclusion
We found that IL-10-592C/A genotype AA and TNF-α-238G/A genotype AA+ AG were significantly associated with reduced risk of hepatitis B infection.
Prediction of Preventive Behaviors of Hepatitis B among Nurses; Insights from the Theory of Planned Behavior
Authors: Mirzaei-Alavijeh Mehdi , Jalilian Fatemeh , Jalilian Farzad 
Published: July 2019

Abstract
Background

Hepatitis B is the cause of the majority of acute and chronic infections, liver cirrhosis and liver cancer in the world. The purpose of current research was to investigation the hepatitis B (HB) preventive behaviors in nurses in west of Iran by using the theory of planned behavior (TPB).

Methods

This cross-sectional research was conducted on 330 nurses from five teaching and treatment hospitals in Kermanshah who were randomly selected. Data were collected by self-report questionnaire. Data were analyzed in the SPSS-16 software by using bivariate correlation, t-test, ANOVA, and linear regression statistical tests.

Results

The mean score for the prevention behaviors of HB was 3.14± 1.45, and the participants achieved 62.8% of the maximum obtainable score for the prevention behaviors of HB. TPB constructs were accounted for 22% of the variation in prevention behaviors of HB, F= 42.351, P< 0.001 and among the TPB constructs, attitude and perceived behavior control were the most influential predictors of doing prevention behaviors of HB.

Conclusions

This research provides a foundation for planning health promotion program to increase the prevention behaviors of HB. It seems our findings are useful in planning health promotion programs aimed at increasing attitude and perceived behavior control to increase the prevention behaviors of HB.
The Effect of Local Government Characteristics on Performance of Local Government Administration
Authors: Utama Fikri Rizki , Evana Einde , Gamayuni Rindu Rika 
Published: July 2019

This study aimed to obtain empirical evidence of the level of regional wealth, the level of dependence to the central government, capital expenditure contribution and legislature size on the performance of local government administration. This research used a purposive sampling method. The study sample consisted of 293 LKPD provinces, districts, municipalities in Indonesia in 2015 which have been audited by the Supreme Audit Board. The result of the research shown that the variables of legislative size had a positive and significant effect on the performance of local government administration while the level of regional wealth, dependency level to the central government and capital expenditure contribution had no significant effect on the performance of the local government.
Identifying the deep groundwater recharge processes in an intermountain basin using the hydrogeochemical and water isotope characteristics
Authors: Shakya Bijay Man , Nakamura Takashi , Shrestha Suresh Das , Nishida Kei 
Published: July 2019

Abstract
The hydrogeochemical and stable isotopes of water (δD and δ18O) were combined to investigate the deep groundwater recharge processes in the geologically complex intermountain basin (Kathmandu Valley). Results of the stable isotopic composition of the deep groundwater compared with global and local meteoric water lines and d-excess showed the deep groundwater as a meteoric water origin which is insignificantly affected by evaporation. The analysis suggests the deep groundwater was recharged during high rainfall periods (wet season). Additionally, the control of seasonal variation was absent in the deep groundwater and in the spring water samples. The large range of isotopic composition distribution was due to the altitude affect, whereas variations are from the various geological settings of the infiltration encountered during the recharge processes. The tri-linear diagram showed Na-K-HCO3 and Ca-Mg-HCO3 as the two major water types. The distribution of water types in this intermountain basin was found to be unique compared to other basins. Ionic concentration of the samples was found to be higher in the central part than in the periphery due to the ion exchange processes. This study determines the spatial distribution of various recharge processes that depends upon the environment during rainfall and the geological settings.
Heavy metal pollution and transboundary issues in ASEAN countries
Authors: Ding Yuanzhao 
Published: July 2019

Abstract
The presence of heavy metals in waterways is a major threat to human health, and such metals cause stomach cancer and brain damage. There is a growing trend towards heavy metal pollution in the Association of Southeast Asian Nations (ASEAN) countries due to inappropriate environmental management and the development of the region's chemical industry. In some border areas, transboundary heavy metal pollution significantly affects people's daily lives. The traditional ASEAN approach to solving heavy metal pollution has limitations due to various problems that affect the ASEAN region, such as unbalanced economic growth, a shortage of environmental technology, and a lack of regional law enforcement. As a result, more effective regional governance on heavy metal pollution and transboundary issues is urgently required. In this paper, network governance theory is used to study environmental problems. This paper recommends that voluntary governance is used to supplement traditional state-centric governance.
Contraste de perspectivas y experiencias sobre compasión de enfermeras colombianas con 14 países
Authors: López-Díaz Lucero , Florisa Velasquez Vilma , Rodríguez Villerland , Papadopoulos Irena 
Published: July 2019

Se exploraron puntos de vista y experiencias sobre compasión en la práctica de enfermeras colombianas y contrasta con los otros 14 países participantes del estudio internacional online. El estudio transversal exploratorio con survey internacional online con 10 preguntas (abiertas y cerradas), contó con 1323 enfermeras, 103 fueron de Colombia. Datos cuantitativos colombianos fueron analizados en Excel y los cualitativos en el programa Nvivo con análisis temático y consenso entre investigadores. La muestra colombiana contó con 83,5% docentes y eligieron la definición de compasión como la “conciencia profunda de sufrimiento de los otros y el deseo de aliviar ese sufrimiento” (84,3%). Piensan que la compasión puede ser enseñada (64,1%) pero no es impartida (45,1%) y es influenciada por la experiencia personal (38,2%) y los valores culturales (37,3%). Los relatos de Colombia revelan barreras sociopolíticos, organizacionales y educativos para la atención compasiva. Perciben compasión de sus pacientes (84,7%), escasa compasión entre colegas (14,3%) y casi nula compasión por parte de los gerentes (1%). Sin embargo, emerge la naturaleza consciente e intencional de la compasión y el esfuerzo de enfermería por desarrollarla en cinco componentes: particularizar, invertir tiempo, estar presente, ir más allá y la defensa/abogacia. Se hacen evidentes algunas variaciones culturales de la compasión y formas de promoverla en un ejercicio profesional cada vez más transcultural.
Autosomal Recessive Non-syndromic Keratoconus: Homozygous Frameshift Variant in the Candidate Novel Gene GALNT14
Authors: Froukh Tawfiq , Hawwari Ammar 
Published: July 2019

Background:
Keratoconus (KC) is usually bilateral, noninflammatory
progressive corneal ectasia in which the cornea becomes progressively thin and conical.
Despite the strong evidence of genetic contribution in KC, the etiology of KC is not
understood in most cases.

Methods:
In this study, we used whole-exome sequencing to identify the genetic cause
of KC in two sibs in a consanguineous family. The Homozygous frameshift variant
NM_001253826.1:c.60delC;p.Leu21Cysfs*6 was identified in the gene Nacetylgalactosaminyltransferase
14 (GALNT14). The variant does not exist in all public
databases neither in our internal exome database. Moreover, no database harbours
homozygous loss of function variants in the candidate gene.

Result:
GALNT14 catalyses the initial reaction in O-linked oligosaccharide biosynthesis,
the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on
target proteins especially Mucins.

Conclusion:
As alterations of mucin’s glycosylation are linked to a number of eye
diseases, we demonstrate in this study an association between the truncated protein
GALNT14 and KC.
Pengaruh Kualitas Pelayanan dan Harga Terhadap Nilai Pelanggan pada Bank Riau Kepri Syariah Tanjungpinang
Authors: Haryani Dwi Septi 
Published: July 2019

<p><em>Sharia-based bank is evolving quite well in Indonesia, one of them is Bank Riau Kepri Syariah residing in Tanjungpinang. A large population of Muslims becomes an opportunity for sharia-based banking business.This research aims to find out how the service quality, price and customer value of Bank Riau Kepri Syariah Tanjungpinang and to know the influence of the service quality and price towards the customer value of Bank Riau Kepri Syariah Tanjungpinang. The population in this research is the customer of Bank Riau Kepri Syariah Tanjungpinang in 2017, using the sample slovin formula with determination. To address the issue of research and hypothesis testing research then used frequency distributive and analysi multiple regression. The results showed that Bank Riau Kepri Syariah Tanjungpinang has a good service quality, reasonable price, and customer value are quite high. The service quality and price effect on the customer’s value simultaneously and partially, the price is more dominant influence to customer’s value than service quality. </em></p><p><em><br /></em></p><p><em>Bank berbasis syariah berkembang cukup baik di Indonesia, salah satunya adalah Bank Riau Kepri Syariah yang berada di Tanjungpinang. Populasi umat islam yang besar menjadi peluang bagi bisnis perbankan berbasis syariah. Penelitian ini bertujuan untuk mengetahui bagaimana kualitas pelayanan, harga dan nilai pelanggan Bank Riau Kepri Syariah Tanjungpinang dan untuk mengetahui pengaruh kualitas pelayanan dan harga terhadap nilai pelanggan Bank Riau Kepri Syariah Tanjungpinang. Populasi dalam penelitian ini adalah nasabah Bank Riau Kepri Syariah Tanjungpinang di tahun 2017 dengan menggunakan teknik penentuan sampel dengan rumus slovin. Untuk menjawab masalah penelitian dan pengujian hipotesis penelitian maka digunakan distribusi frekuensi dan analisis regresi berganda. Hasil penelitian menunjukkan bahwa Bank Riau Kepri Syariah Tanjungpinang memiliki kualitas pelayanan yang baik, harga yang wajar, dan nilai pelanggan yang cukup tinggi. Kualitas pelayanan dan harga berpengaruh terhadap nilai pelanggan secara simultan dan secara parsial harga lebih dominan mempengaruhi nilai pelanggan dibandingkan kualitas pelayanan.</em></p>
KUALITAS TES KOMPETENSI TUKANG ACI DAN PLESTERAN BERDASARKAN KKNI (PU)
Authors: Maulana Ivan 
Published: July 2019

Penguasaan kompetensi merupakan prioritas yang harus dimiliki oleh setiap tukang dalam melaksanakan pekerjaan, untuk mengukurnya diperlukanlah sebuah instrumen. Instrumen harus dapat menjadi acuan penilaian kompetensi tukang sesuai dengan standar yang ada dan kebutuhan di lapangan dalam upaya menciptakan tukang yang berkualitas dan mampu beradaptasi dengan perkembangan industri saat ini. Penelitian ini bertujuan untuk mengetahui apakah instrumen pekerjaan plesteran yang berlaku telah sesuai dengan standar dan kebutuhan lapangan. Rancangan penelitian menggunakan pendekatan kualitatif dengan teknik pengumpulan data berupa kuisioner yang ditujukan ke panel ahli dalam memperoleh justifikasi terhadap instrumen yang sudah ada. Dari hasil penelitian berdasarkan justifikasi ahli diperoleh bahwa beberapa item pekerjaan tidak sesuai dengan implementasi di lapangan saat ini, serta penggunaan metode penilaian yang digunakan kurang tepat pada instrumen yang ada. Manfaat penelitian ini diharapkan dapat menjadi referensi dalam mengembangkan instrumen pekerjaan plesteran Kata kunci: kompetensi, instrument, plesteran
PENGEMBANGAN MODUL PEMBELAJARAN MATA KULIAH INTERNET OF THINGS
Authors: Gde Ekayana Anak Agung 
Published: July 2019

Penelitian ini bertujuan menghasilkan modul pembelajaran untuk mata kuliah Internet of Things, modul yang disusun berupa modul cetak. Modul ini disusun karena didasari perubahan kurikulum yang ada di Program Studi Sistem Komputer STMIK STIKOM Indonesia, adanya perubahan kurikulum tentunya ada beberapa penambahan matakuliah baru, salah satunya Internet of Things (IoT). Implikasi dari pengembangan kurikulum berdampak pula pada proses pembelajaran, sehingga dipandang perlu untuk menyusun materi menjadi sebuah sumber belajar yang relevan, salah satunya berupa modul pembelarajran. Metode yang digunakan dalam pengembangan modul ini adalah model pengembangan ADDIE, model ini digunakan karena tahapan pengembangannya lebih sederhana dan waktu yang digunakan tidak terlalu lama. Hasil dari penelitian ini berupa modul pembelajaran IoT versi cetak, untuk menentukan kelayakan penggunaan modul ini telah dilakukan uji coba, antara lain uji coba perorangan dan uji coba kelompok kecil. Pada pengujian perorangan melibatkan 3 orang mahapeserta didik Sistem Komputer yang diambil secera acak dan sudah pernah mengambil Mata Kuliah IoT, sedangkan pengujian kelompok kecil melibatkan 9 orang mahapeserta didik Sistem Komputer. Hasil dari uji coba tersebut adalah pada uji coba perorangan memperoleh hasil rerata 91,94% dan uji coba kelompok kecil memperoleh 86,67%, selanjutnya angka tersebut dimasukkan pada tabel skor kelayakan kontinum dan hasilnya menyatakan bahwa modul pembelajaran Internet of Things dianggap layak digunakan dalam proses pembelajaran.
Tipe Kepribadian Big Five, Sense of Humor dan Subjective Well-Being pada Mahasiswa UIN Suska Riau
Authors: Zulfadri Deddi , Raudatussalamah Raudatussalamah 
Published: July 2019

Abstrak Mahasiswa dalam proses pengembangan ilmu pengetahuan dan teknologi diperguruan tinggi dihadapkan dengan banyaknya tuntutan. Tuntutan ini mengakibatkan tekanan yang memunculkan masalah-masalah psikologis. Evaluasi mahasiswa terhadap pengalaman masalah-masalah yang terjadi disebut dengan subjective well-being. Banyak faktor yang mempengaruhi subjective well-being, diantaranya tipe kepribadian big five dan sense of humor. Penelitian ini bertujuan untuk mengetahui hubungan antara tipe kepribadian big five dan sense of humor dengan subjective well-being mahasiswa UIN Suska Riau. Jumlah subjek dalam penelitian ini sebanyak 393 orang. Analisa data yang digunakan dalam penelitian ini adalah teknik analisis regresi ganda. Hasil analisa menunjukkan hubungan yang signifikan antara tipe kepribadian big five dan sense of humor dengan subjective well-being dengan signifikansi sebesar 0,000. Sumbangan efektif tipe kepribadian big five dan sense of humor terhadap subjective well being sebesar 10,6%. Hasil uji hipotesis minor diperoleh dua koefisien regresi yang signifikan hubungan terhadap subjective well-being yaitu tipe kepribadian conscientiousness sebesar p = 0,000 dan sense of humor sebesar p = 0,000. Kata Kunci: Tipe Kepribadian Big Five, Sense of Humor, Subjective Well-Being
An evaluation on sustainable tourism demand: The case of Muğla, Turkey
Authors: BAHAR Ozan , ÇELİK İLAL Nur 
Published: July 2019

Tourism sector that is one of the most important, driving power of
social, economic and cultural development, has a significant role, especially
for developing countries. In this sense, the countries aiming to get a bigger
share in tourism have to carefully observe the fast progression in this sector
and fulfill the changing expectations of the customers. In order to fulfill quality service and
customer satisfaction, sustainability is very important in the sector in
general. In this study which primarily discusses sustainable tourism,
sustainable tourism practices affecting tourism demand will be referred. The
ultimate aim of this research is to evaluate the level of the effect of
sustainable tourism practices on tourism demand. The sample of the study is
a total of 600 persons of foreign tourists who visited Mugla. According to data
acquired from the questionnaires; protection of ecological, cultural and
natural heritage, slow city, eco-label, concept and the competition power of
the enterprise are the affecting factors on the tourism demand. Such results
showed that sustainable tourism practices influence tourism demand
positively.