bluuebunny/crossref_metadata_2025_split huggingface dataset:
Longitudinal association of remnant cholesterol with cognitive decline vary by lipid-lowering therapy: a population-based cohort study
Authors: Hua Jianian , Dong Jianye , Chen Ying , Li Haibin , Chen Qingmei 
Published: November 2024

AbstractObjectiveAlthough the association between remnant cholesterol (RC) and cognitive impairment has been reported, the association of RC with cognitive decline remains scarce. Also, the role of lipid- lowering therapy in the association is unclear. The study aimed to examine the longitudinal associations of RC with cognitive decline by lipid-lowering drug use status.MethodsThe study utilized data from wave 2 (2004-2005) to wave 8 (2016-2017) of the English Longitudinal Study of Ageing (ELSA). Global cognitive functions at baseline (wave 2) and during the follow-up (waves 3-8) were assessed by integrating three cognitive domains, including memory capacity, semantic fluency, and orientation. Multivariate-adjusted linear mixed models were employed to examine the longitudinal associations, with results presented asβ[95% confidence interval (CI)] in standard deviation (SD)/year.ResultsOf the 5053 participants ultimately included, 55.4% were female and the mean age (SD) was 65.7 (9.3) years. Per 1 mmol/L increment in RC was significantly associated with a faster rate of cognitive decline (β= −0.010 SD/year, 95% CI: -0.019, -0.001). Furthermore, we observed that the association pattern between RC and cognitive decline only in the non-lipid-lowering drug group (β= -0.019 SD/year, 95% CI: -0.031, -0.007), but not in the lipid-lowering drug group (β= 0.007 SD/year, 95% CI: -0.006, 0.020), with a significant interaction (P= 0.015). Similar findings were observed for the three cognitive domains.ConclusionsHigher baseline RC levels were associated with steeper cognitive decline. Regular use of lipid-lowering drugs during follow-up might attenuate the accelerated cognitive decline caused by high RC.
IL-33 protects from recurrentC. difficileinfection by restoration of humoral immunity
Authors: Naz Farha , Hagspiel Nicholas , Young Mary K. , Uddin Jashim , Tyus David , Boone Rachel , Brown Audrey C. , Ramakrishnan Girija , Rigo Isaura , Madden Gregory R. , Petri William A. 
Published: November 2024

ABSTRACTClostridioides difficile infection (CDI) recurs in one of five patients. Monoclonal antibodies targeting the virulence factor TcdB reduce disease recurrence, suggesting that an inadequate anti-TcdB response to CDI leads to recurrence. In patients with CDI, we discovered that IL-33 measured at diagnosis predicts future recurrence, leading us to test the role of IL-33 signaling in the induction of humoral immunity during CDI. Using a mouse recurrence model, IL-33 was demonstrated to be integral for anti-TcdB antibody production. IL-33 acted via ST2+ ILC2 cells, facilitating germinal center T follicular helper (GC-Tfh) cell generation of antibodies. IL-33 protection from reinfection was antibody-dependent, as μMT KO mice and mice treated with anti-CD20 mAb were not protected. These findings demonstrate the critical role of IL-33 in generating humoral immunity to prevent recurrent CDI.Abstract FigureGraphical Abstract:IL-33 restoration induces toxin-B-specific antibody production via the ILC2-TFH axis. In the left panel, IL-33 remediation increases ILC2s, subsequently inducing TFH directly or indirectly. TFH cell induction is pivotal for the production of antibodies. IL-33 also downregulates type 1 and type 3 immunity, favoring type 2 immunity to enhance host survival and reduce morbidity.The middle panel illustrates antibiotic-induced dysbiosis, resulting in decreased IL-33 levels and reduced antibody production.The right panel demonstrates the protective effect in reinfection, attributed to toxin-specific antibodie generated by IL-33 remediation.
What are the ethnic inequities in care outcomes related to haematological malignancies, treated with transplant/cellular-therapies, in the UK?
Authors: Cusworth Samuel , Deplano Zareen , Denniston Alastair , Burns David , Nirantharakumar Krishnarajah , Adderley Nicola J , Chandan Joht Singh 
Published: November 2024

AbstractIntroductionHaematological cancers are common in the UK, with a variety of morphologies. Stem cell transplants and chimeric antigen receptor (CAR) T-cell therapies provide significant options for hard to treat haematological cancers, although with difficult to predict outcomes. Research into the determinates of treatment efficacy, and access to treatments, is key to ensuring equal benefit across patients, and patient safety. With this, there are concerns about the small representation of minority groups in related research. We aim to report on the current knowledge, to guide future research.Methods and analysisA variety of databases will be searched, for literature on UK minority ethnic populations receiving haematopoietic stem cell transplant or CAR T-cell therapy. Many outcomes will be analysed, covering the patient care pathway for those of the target population, although with a focus on follow-up after therapy. Plans have been made to conduct narrative synthesis, with meta-analysis where applicable.Ethics and DisseminationOutputs will be published in an appropriate journal, and discussed with the wider NIHR Blood and Transplant Research Unit in Precision Transplant and Cellular Therapeutics (BTRU) group. Discussions will also be undertaken with the BTRU patient partners group.Strengths and Limitations of this StudyThis systematic review has a detailed search criteria with a variety of search tools, enabling high sensitivity in obtaining evidence.To enable this work to be completed, reviewers will be working independently on separate reference lists, during screening, rather than voting on the same references and resolving conflicts. To alleviate issues, reviewers will be first required to screen a defined number of papers together, using a more classical approach to confirm agreement, before working independently.Due to difficulties in pooling together international ethnic groups, only studies in the UK have been included, to reduce complexity. There are some ethnic groups which are more valid to pool together internationally than others, mainly in respect to genetic factors (as opposed to social), which this protocol does not consider.
Self-organized acoustic behavior in bats arises from simple rules
Authors: Hase Kazuma , Miyazaki Tasuku , Oka Seiya , Senoo Noriyoshi , Nishimori Hiraku , Shiraishi Masashi , Yoda Ken , Kobayasi Kohta I , Hiryu Shizuko 
Published: November 2024

AbstractAlthough self-organized behavior has been extensively studied in the movement of group-behaving animals, such as fish or birds, far less attention has been paid to vocal behavior in animal groups, especially in mammals. Here, by testing the vocal response of echolocating bats (Miniopterus fuliginosus) to the playback of jamming stimuli in the lab, we discovered a mathematical model that can well describe vocal frequency control by bats in response to jamming stimuli mimicking echolocation sounds emitted in a group of bats. We then extended the model to a group of flying bats and observed frequency-adjusting behavior by which the frequency differences for the group increased overall, similar to a previous observation on group-flying bats. Further, we showed the frequency-adjusting behavior led to less potential misdetections by echolocation in a group. Our findings suggest this frequency-adjusting behavior is a self-organized vocal behavior that mitigates conflicts within a group, one achieved via simple behavioral rules, as in other types of collective animal behavior.
First-principles study and mesoscopic modeling of two-dimensional spin and orbital fluctuations in FeSe
Authors: Ghosh Abyay , Chudzinski Piotr , Grüning Myrta 
Published: November 2024

We calculated the structural, electronic, and magnetic properties of FeSe within density-functional theory at the generalized gradient approximation level. First, we studied how the bandwidth of the d-bands at the Fermi energy is renormalized by adding simple corrections: Hubbard U, Hund's J, and by introducing long-range magnetic orders. We found that introducing either a striped or a staggered dimer antiferromagnetic order brings the bandwidths—which are starkly overestimated at the generalized gradient approximation level—closer to those experimentally observed. Second, for the ferromagnetic, the striped, checkerboard, and staggered dimer antiferromagnetic order, we investigate the change in magnetic formation energy with local magnetic moment of Fe at a pressure up to 6 GPa. The bilinear and biquadratic exchange energies are derived from the Heisenberg model and noncollinear first-principles calculations, respectively. We found a nontrivial behavior of the spin-exchange parameters on the magnetization, and we put forward a field-theory model that rationalizes these results in terms of two-dimensional spin and orbital fluctuations. The character of these fluctuations can be either that of a standard density wave or a topological vortex. Topological vortices can result in mesoscopic magnetization structures.

Published by the American Physical Society
2024
Embedded multi-boson exchange: A step beyond quantum cluster theories
Authors: Kiese Dominik , Wentzell Nils , Krivenko Igor , Parcollet Olivier , Held Karsten , Krien Friedrich 
Published: November 2024

We introduce a diagrammatic multi-scale approach to the Hubbard model based on the interaction-irreducible (multi-boson) vertex of a small cluster embedded in a self-consistent medium. The vertex captures short-range correlations up to the length scale of the cluster, while long-range correlations are recovered from a set of diagrammatic equations for the Hedin three-leg vertex. By virtue of the crossing symmetry, the Fierz decoupling ambiguity of the Hubbard interaction is resolved exactly. Our benchmarks for the half-filled Hubbard model on the square lattice are in very good agreement with numerically exact diagrammatic Monte Carlo simulations.

Published by the American Physical Society
2024
Rural households' livelihood transitions in China: processes, drivers and outcomes
Authors: Cui Hongping , Wang Ying , Wang Weiwen , Liu Chongchong 
Published: November 2024

PurposeThis study aims to comprehensively examine the transitions in household livelihood strategies within rural China, including the underlying processes, drivers and outcomes.Design/methodology/approachThis study uses two waves (2010 and 2018) of longitudinal data from the China Family Panel Studies (CFPS), employing latent cluster analysis, regression models and cumulative distribution function within a dynamic household livelihood strategy framework.FindingsThe results show that (1) households’ livelihood strategies can be categorized into four distinct types, i.e. agricultural dominated, agricultural dominated with non-agricultural supplementation, non-agricultural dominated with agricultural supplementation and employment oriented. (2) During 2010–2018, approximately 60% of households underwent transitions in their livelihoods, encompassing both upward and downward trajectories, with a prevalence of upward transitions. (3) Various forms of livelihood capital significantly contribute to upward transitions, while the availability of land resources and exposure to shocks impede the potential for upward mobility. (4) The transition towards non-agricultural livelihood strategies by households leads to a notable enhancement in their livelihood welfare.Research limitations/implicationsIn the context of urbanization, industrialization and globalization, rural areas in China are undergoing a gradual socioeconomic transformation, which has also led to changes in rural households’ livelihood strategies. Nevertheless, a dearth of empirical investigation exists regarding the dynamics of rural households’ livelihood strategies, the determinants behind such transitions and the resulting outcomes on their livelihoods. A comprehensive understanding of livelihood transitions can provide valuable insights for policymakers in their endeavors to promote rural revitalization in China.Originality/valueBased on the nationwide representative datasets in China, it examines the micro-level livelihood transitions of rural households within the broader context of socioeconomic transformation that presents both opportunities and challenges, as well as vulnerable contexts, shaped by various government policies. This exploration would offer valuable theoretical and empirical evidence to advance our understanding of the process, driver and outcome of rural households’ livelihood transition in developing countries.
Exploring determinants of visitor’s e-WOM in the virtual art exhibition with an extended American Customer Satisfaction Index Model
Authors: Wang Xi , Liao Yiqing , Liu Chuyao , Zheng Jie 
Published: November 2024

Purpose
By applying the American Customer Satisfaction Index (ACSI) model to virtual art exhibitions, this research aims to reveal insights into the factors impacting visitor satisfaction and electronic word-of-mouth (e-WOM). Furthermore, the investigation of exhibition promotion seeks to understand how external factors contribute to the overall visitor experience in virtual art exhibitions.

Design/methodology/approach
With advancements in virtual communication technology and the transformative impact of the COVID-19 pandemic in recent years, there has been a notable surge in the popularity of virtual art exhibitions based on the Internet. This study uses the ACSI model to examine visitor satisfaction and e-WOM in virtual art exhibitions. Additionally, it explores the influence of exhibition promotion on the ACSI model.

Findings
Key findings revealed that 1) both promotion efforts and e-WOM exhibited significant relationships with the ACSI model, and 2) most of the relationships within the ACSI model were consistent with previous research outcomes.

Originality/value
This study extends the ACSI model’s application to virtual art exhibitions, enhancing its relevance. Additionally, it addresses the knowledge gap concerning the direct impact of promotion on audience expectations and its relationship with the ACSI model in virtual art exhibitions. Furthermore, the research explores the influence of customer satisfaction on electronic word-of-mouth in exhibitions, offering valuable insights for exhibition evaluation systems. The study serves as a guide, providing data and models for researchers investigating virtual art exhibitions.
Uncorking the delights: deciphering Indian wine consumers’ tastes with a multi-method approach and consumer insights
Authors: Sukumaran Likhil , Majhi Ritanjali 
Published: November 2024

Purpose
Alcohol consumption trends in India have undergone a significant shift in recent years. While spirits like rum and brandy have traditionally dominated the Indian alcohol industry, wine is now gaining popularity with a commendable compounded annual growth rate. This presents a significant opportunity for wine marketers to develop effective strategies for targeting Indian consumers. To capitalise on this evolving market scenario, it is crucial to understand the attributes that consumers seek in their preferred wines. Therefore, this study aims to identify the specific wine attributes that significantly influence the purchasing behaviour of Indian consumers.

Design/methodology/approach
The study used a mixed-methods approach to comprehend the wine preferences of Indian consumers. The methods included tweet analysis, word cloud, sentiment analysis and conjoint analysis.

Findings
The study reveals that Indian millennials’ wine consumption is driven by health and sustainability concerns, particularly the appeal of organic and low-alcohol options. However, wine, especially red wine, is also strongly associated with socializing, luxury and pleasure. This dual motivation highlights wine’s versatility in fulfilling both health-conscious and indulgent desires.

Originality/value
This study examines Indian wine consumers and their purchasing decisions using a multi-method approach. In addition, it compares gender preferences, addressing a gap in limited research on the Indian wine industry.
The effect of surface roughness and carburized depth on wear resistance in 16MnCr5 case hardening steel
Authors: Baykara Celalettin , Atik Enver 
Published: November 2024

Purpose
Today, wear and tear is a metaphor whose cost cannot be ignored by real sector. For this reason, many sectoral and academic studies are carried out to minimize the wear effect. This study aims to create a perspective against wear problems for the automotive industry as well.

Design/methodology/approach
The 16MnC5 material, which is used as the U-joint material in the powertrain of the automotive industry, was subjected to heat treatment such as normalization and carburization at certain temperatures and duration. By subjecting the resulting carbide thickness to the abrasion process, the maximum effective heat treatment parameters against wear were determined.

Findings
It has been determined that the ideal cementation condition for 16MnCr5 steel to be used in the wear system is carburized samples at 900 °C for 3.5 h with a hardness depth of 1.04 mm.

Originality/value
The variation in which the surface hardness thickness and surface roughness obtained by different heat treatment variations of the U-joint part, which is one of the cardan shaft components that provide power transmission of heavy commercial vehicles, show the best wear resistance, were investigated. As a result of this study, the study is to prevent the waste of limited materials in the world and to reduce the repair and maintenance costs of commercial vehicles.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-05-2024-0152/
The components of perceived quality and their influence on online re-purchase intention
Authors: Kumar Rahul , Jain Varsha , Eastman Jacqueline Kilsheimer , Ambika Anupama 
Published: November 2024

Purpose
This study aims to understand holistic consumer perceptions of quality and their effect on re-purchase intentions by measuring the latent characteristics of online Amazon reviews.

Design/methodology/approach
Data was collected from entries in the Amazon customer review data set, which explicitly mentions quality, economic evaluation and future purchase intention. The analyses included natural language processing, structural topic modeling and econometric analysis. The study used real-time customer reviews to determine the overall perceived quality, the impact of perceived quality on re-purchase intention and the mediating roles of price consciousness and customer satisfaction.

Findings
Consumers’ perception of overall quality includes product- and service-related dimensions. Perceived quality influences re-purchase intentions through the mediating role of customer satisfaction. While price consciousness impacts the link between perceived quality and customer satisfaction, it does not affect re-purchase intention.

Practical implications
The managerial implications emphasize multiple dimensions of quality in the online environment and the role of customer satisfaction in consumers’ online re-purchase intentions. The results also illustrate that price effects are insignificant in influencing re-purchase intentions. Thus, while price cuts may encourage initial purchases, quality and customer satisfaction are vital to stimulate re-purchase.

Originality/value
The e-commerce literature lacks a comprehensive and rigorous understanding of the components of consumers’ perceived quality. This research develops a thorough understanding of what impacts overall e-commerce quality based on real-time customer reviews, avoiding the biases arising from traditional methods, including surveys.
Artificial intelligence in hospitality services: examining consumers’ receptivity to unmanned smart hotels
Authors: Du Huiying , Li Jing , So Kevin Kam Fung , King Ceridwyn 
Published: November 2024

PurposeWith recent advances in artificial intelligence, the hospitality industry has introduced the concept of unmanned smart hotels staffed by service robots instead of human employees. Research is needed to understand consumers’ receptivity to such an innovation. This paper examines factors associated with consumers’ potential resistance to using automated service hotels via two sequential studies. Given that younger generations of consumers are typically early adopters of advanced technology and innovative services, our sampling approach focused on this consumer group.Design/methodology/approachTwo studies were conducted. Study 1 proposed and empirically tested a theoretical model. Results revealed that attitude, subjective norms and perceived behavioral control each positively influenced individuals’ intentions to use unmanned smart hotels. In Study 2, we further investigated aspects informing perceived security, a key variable in the use of unmanned smart hotels.FindingsFindings showed how people’s beliefs about unmanned smart hotels and security control assurances led to perceived security. These perceptions were shaped by perceived physical risks, privacy concerns, website design and hotel reputation. Overall, this research provides theoretical and practical implications for various stakeholders associated with unmanned smart hotels.Practical implicationsFindings of this study suggested that managers of unmanned smart hotels should design user-friendly, secure processes and offer comprehensive support resources to enhance customer experience and usage.Originality/valueThe findings provide a holistic understanding of consumers’ receptivity to unmanned smart hotels.
The impact of organizational dehumanization on creative performance through self-esteem threat: the moderating role of work locus of control
Authors: Talpur Qurat-ul-ain , Khan Rahman , Malik M. Abdur Rahman , Murtaza Ghulam 
Published: November 2024

PurposeThis paper aims to enhance our understanding of how organizational dehumanization affects employees’ creative performance. We propose the self-esteem threat as a mediator in the relationship between organizational dehumanization and employees’ creative performance. We also examine how work locus of control moderates the relationship between organizational dehumanization and creative performance.Design/methodology/approachThrough convenience sampling, online and face-to-face surveys, multisource time-lagged data (N = 257) were collected from full-time employees and their supervisors in Pakistani organizations in the information technology, media industry and oil and gas sectors.FindingsOrganizational dehumanization negatively affects employees’ creative performance, and threats to self-esteem mediate this relationship. Work locus of control moderates the effect of organizational dehumanization on creative performance, and this negative relationship is attenuated when individuals have an external work locus of control.Originality/valueThis study provides novel insights into the process underlying the relationship between organizational dehumanization and creative performance by revealing the mediating role of threat to self-esteem and the buffering role of work locus of control.