bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Propolis Extract To Increase Fibroblast In Remodeling Process at Tension Side of Orthodontic Tooth Movement
Authors: Handayani Budi , Mardanus Lisdiana 
Published: July 2019

<p><strong><em>Background:</em></strong><em> </em><em>O</em><em>rthodontic treatment</em><em> requires</em><em> time</em><em> so, duration of orthodontic treatment time needs to be shortened in</em><em> various ways<strong>. </strong></em><em>Flavonoid is an active content of propolis, that might accelerate tissue regeneration. Flavonoid might</em><em> increase the number of</em><em> </em><em> fibrobla</em><em>st</em><em> </em><em>at</em><em> tension side of </em><em>orthodontic </em><em>tooth movement. <strong>Purpose:</strong></em><strong><em> </em></strong><em>T</em><em>he purpose of this study was to examine the effect of</em><em> propolis extract </em><em>gel towards the number </em><em>of </em><em> fibroblas</em><em>ts</em><em> </em><em>at</em><em> tension sid</em><em>e to accelerate orthodontic tooth movement. <strong>Materials and </strong></em><strong><em>Methods:</em></strong><em> </em><em>T</em><em>hirty</em><em> male Cavia </em><em>c</em><em>obaya</em><em>s</em><em> were div</em><em>i</em><em>ded into </em><em>three</em><em> groups. The first group</em><em>, (</em><em> </em><em>P) </em><em>wa</em><em>s given treatment </em><em>to make orthodontic tooth movement </em><em>and </em><em>propolis extract</em><em> ge</em><em>l.</em><em> </em><em>The second group</em><em>,</em><em> K(+) </em><em>wa</em><em>s given treatment and NaCMC gel. The third group</em><em>,</em><em> </em><em>K(-) </em><em>wa</em><em>s served as control. </em><em>After 14 days, the Cavia cobayas were sacrified. Fibroblast number was examined with light microscope 400 X. </em><strong><em>Result: </em></strong><strong><em> </em></strong><em>Mean<strong> </strong>and SD in K(-):100 ± 13,2; K(+):80 ± 13,05; (P):176 ± 17,9.<strong> </strong></em><em>The result of ANOVA test showed significa</em><em>nt</em><em> in</em><em>crease</em><em> in the number of fibroblas</em><em>ts</em><em>.</em><em> The </em><em>LSD</em><em> test showed significant result</em><em> in all groups </em><em>with</em><em> significance result p ≤ 0,05. </em><strong><em>Conclusion:</em></strong><em> </em><em>Propolis extract can increase fibroblast number to accelerate orthodontic tooth movement.</em></p><p><em> </em></p><p><strong><em>Keywords: </em></strong><em>O</em><em>rthodontic</em><em> tooth movement</em><em>,</em><em> propolis extract</em><em>, Cavia </em><em>c</em><em>obaya</em><em>,</em><em> fibroblas</em><em>t</em><em>.</em><em></em></p><p><em> </em></p><p><strong><em>Correspondence:</em></strong><em> Departement of </em><em>Orthodontics, </em><em>Faculty of Dentistry, </em><em>Hang Tuah</em><em> University</em><em>, Arif Rahman Hakim 150, Surabaya,</em><em> Phone </em><em> 031-594864, </em><em>Fax </em><em> 031-5912191</em><em>, Email: </em><a href="mailto:yukira.yaniela@gmail.com"><em>yukira.yaniela@gmail.com</em></a><em></em></p>
Increasing Performance Treatment Index’s Score (PTI) of Elementary School Children in Keputih-Surabaya Through Dental Public Health Warrior Project
Authors: Maharani Aulia Dwi 
Published: July 2019

<p><strong><em>Introduction:</em></strong><em>The </em><em>Dental Public Health Warrior (DPHW) project is a social activity which provides a creative, fun</em><em>,</em><em> and interactive dental health education throughout elementary schools in Keputih Area-Surabaya,Indonesia. <strong>Purpose:</strong> The aim of this study was to determine the effectivity of those project</em><em>s</em><em> in increasing the Performance Treatment Index of elementary school’s student. PTI score used to measure the willingness to treat their teeth. <strong>Materials and Methods:</strong></em><em>In this </em><em>pre experimental study (pretest and posttest only design), subjects were 54 elementary students (4th grade) . All subjects were educated by </em><em>the </em><em>DPHW </em><em>t</em><em>eam and their DMF-t score and PTI score were collected by calibrated dentists before the education and in 3 months after the education. <strong>Results:</strong> The mean of DMF-t score increase from 6,7 to 6,9. The mean of PTI score increase from 3,7 to 9,5 . Wilcoxon analysis showed there is significant different between before and after education (p= 0,001). <strong>Conclusion:</strong>. </em><em>The </em><em>DPHW project can be effectively used to increase the Performance Treatment Index of elementary school’s student. The increase of PTI indekx means there is increase in willingness to treat their teeth.</em></p><p><em> </em></p><p><strong><em>Keywords: </em></strong><em>Dental Public Health Warrior Project, PTI score , Performance Treatment Index,</em><em>elemntary school, Surabaya.</em></p><p><strong><em> </em></strong></p><p><strong><em>Corrrespondence:</em></strong><em>Aulia Dwi Maharani, </em><em>Department of </em><em>Public Health, Faculty of Dentistry, Hang Tuah</em><em> University</em><em>,Arif Rahman Hakim 150, Surabaya,</em><em>Phone 031-</em><em>5945864</em><em>, </em><em>Email: </em><a href="mailto:aulia.maharani@hangtuah.ac.id"><em>aulia.maharani@hangtuah.ac.id</em></a>.</p>
Bioviability of Mangrove Leaves Extract (Sonneratia alba) on Fibroblast BHK-21 Cell Culture
Authors: Charyadie Arlita Gladys Tricia , Aprilia Aprilia , Widyastuti Widyastuti 
Published: July 2019

<p><strong>Background:</strong> Dental caries is a major oral health problem which is most commonly found in Indonesia. One of the main factors in role of causing dental caries is Streptococcus mutans which is the primary target of the prevention of caries. Leaf extract of Sonneratia alba has<br />been proven to have an antimicrobial effect towards Streptococcus mutans, but its cytotoxic activity on normal cells is still unknown. The initial cell viability in this study was conducted using cell line BHK-21. <strong>Purpose:</strong> The aim of this study is to determine the cell viability of<br />fibroblast cells line BHK-21 by given Sonneratia alba’s leaf extract. <strong>Materials and Methods:</strong> The experiment was conducted using post test only control group design. BHK-21 fibroblast cell culture on 96 wells were divided into cell control group (n=9), media control group (n=9) and test groups (n=9). The test groups were given various concentration of Sonneratia alba’s leaf extract, they were: 5%; 10%; and 20%. The cell cultures were incubated for 24 hours before and after treatment using Sonneratia alba’s leaf extract. After dripping MTT into the microplates, OD were read using ELISA reader and the viability were counted. The data that was acquired from the viability calculation was statistically analyzed using One Way ANOVA and LSD test. <strong>Results:</strong> Data showed the increase of viability cell in all the test groups. The highest viability cell showed by the test group with 10% concentration of Sonneratia alba (153,7122%±7,42458), and the lowest found in the test group with 20% concentration of leaf extract (141,4682%±7,48752). <strong>Conclusion:</strong> In this experiment, the leaf extract of Sonneratia alba proved to be nontoxic on fibroblast cells line BHK-21, the extract increased the viability and also caused proliferation of fibroblast cells.</p><p> </p><p><strong>Keywords:</strong> Dental caries, Sonneratia alba, fibroblast, viability, cell culture</p><p><strong><br /></strong></p><p><strong>Correspondence:</strong> Aprilia, Department of Conservation, Faculty of Dentistry, Hang Tuah Univesity, Arif Rahman Hakim 150, Surabaya, Phone 031-5945864, Email: <span style="text-decoration: underline;">drg.aprilia.spkg@gmail.com</span></p>
Effectiveness of Chitosan Solution as Denture Cleanser to Inhibit the Growth of Candida albicans on Acrylic, Valplast and Luciton-FRS
Authors: Apsari Anindita , Ariestania Vivin 
Published: July 2019

<p><strong><em>Background: </em></strong><em>Heat cure acrylic and nylon thermoplastic valplast and lucitone-FRS brands are the three materials most often used as denture bases. Candida albicans is the dominant microorganism that can cause denture stomatitis. Cleaning denture can be done in two ways, namely the mechanical way with a toothbrush or an ultrasonic cleanser and a chemical method by immersing the denture into the cleaning solution. Chitosan solution is antibacterial and anti fungal which can inhibit the growth of Candida albicans colonies on heat cured acrylic plates, valplast and lucitone-FRS. <strong>Purpose:</strong> To determine the concentration of chitosan solution and the type of denture plate that most effectively inhibited the growth of Streptococcus mutans Candida albicans colonies on heat cured acrylic, valplast and lucitone-FRS plates. <strong>Materials and Methods: </strong>21 heat cured acrylic plate samples, 21 valplast plate samples, 21 lucitone-FRS plate samples measuring 10x10x2 mm divided by 9 groups. Heat cured, valplast and lucitone-FRS acrylic plate samples were contaminated with Candida albicans then immersed using the concentration of 0.25%, 0.5% chitosan solution and sterile aquades as the control group with 90 minutes immersion time. The entire study sample was calculated using Candida albicans colonies on Sabourroud's Dextrose Agar media. <strong>Results: </strong>The Kruskall Wallis test showed a significant difference (p &lt;0.05) in all treatment groups. Mann-Whitney showed a significant difference (p &lt;0.05) in all groups in the Candida albicans study. <strong>Conclusion: </strong>Soaking the lucitone-FRS plate in 0.5% chitosan solution for 90 minutes was the most effective in inhibiting the growth of Candida albicans colonies.</em></p><p><strong> </strong></p><p><strong><em>Keywords:</em></strong><em>Kitosan, Candida albicans, akrilik heat cured, valplast, lucitone-FRS</em></p><p><strong><em> </em></strong></p><p><strong><em>Correspondence: </em></strong><em>Anindita Apsari, </em><em>Department of Prosthodontics, Faculty of Dentistry, Hang Tuah University, Arif Rahman Hakim 150, Surabaya</em><em>, Email : </em><a href="mailto:anindita.apsari@hangtuah.ac.id"><em>anindita.apsari@hangtuah.ac.id</em></a><em>/</em><a href="mailto:drg.anindita@gmail.com"><em>drg.anindita@gmail.com</em></a><em></em></p>
Effectiveness of PRP (Platelet Rich Plasma) To Increased BMD (Bone Mineral Density) At Maxilla Dental Implant Placement with 3-Dimensional Radiographic Examination (CBCT)
Authors: Saptaswari Dianty , Widyatuti Widyatuti , Wedarti Yoifah Rizka , Kurniawan Hansen 
Published: July 2019

<p><strong><em>Background:</em></strong><em> Dental implant is a device that is surgically implanted into the soft tissue or into the jaw bone. dental implants have become the treatment of choice for replacing missing teeth. Platelet rich plasma and platelet concentration derived from autologous blood containing autologous growth factors in which the platelet rich plasma can improve wound healing and increase the regeneration of bone. today cone beam computed tomography (CBCT) has been available for 3D visualization of craniofacial section. CBCT 3 D is able to provide information on the general bone mineral density. </em><strong><em>Purpose:</em></strong><em> </em><em> T</em><em>he purpose</em><em> </em><em>of</em><em> </em><em>this studywas to determine thebone mineral density</em><em> </em><em>by</em><em> </em><em>three</em><em>-dimensional radiographic</em><em> </em><em>picture</em><em> </em><em>after</em><em> </em><em>dental</em><em> </em><em>implant placementbyan additional</em><em> </em><em>plateletrich plasma.</em><em> </em><strong><em>Material and Method:</em></strong><strong><em> </em></strong><em>This study was divided into 2 groups. The first placement of a dental implant with platelet rich plasma and the second placement of a dental implant without platelet rich plasma. <strong>Results:</strong> there are significant differences in dental implant placement with platelet rich plasma and placement of dental implants without platelet rich plasma. In the test results obtained Independent T test (p = 0.02). <strong>Conclusion:</strong> There was an increase bone mineral density in dental implant placement with platelet rich plasma were performed using three-dimensional radiographic examination (CBCT).</em></p><p><strong><em>Keyword:</em></strong><strong><em> </em></strong><em>Dental implant, platelet rich plasma, CBCT, bone density</em></p><p><strong><em>Correspondence:</em></strong><strong><em> </em></strong><em>Dianty Saptaswari, Widyatuti, Yoifah Rizka Wedarti, Hansen Kurniawan</em><em> </em><em>Periodonsia Fakultas Kedokteran Gigi Universitas Hang Tuah Surabaya</em><em>, </em><em>Email : <a href="mailto:anthie.dent@gmail.com">anthie.dent@gmail.com</a></em></p>
Role of C-type Lectin Receptor to C.albicans on Promotion of Inflamantory Diseases
Authors: Sulistyani Erna 
Published: July 2019

<p><em>In early 2010 there was a very rapid progress in the development of immunity to fungi, i.e the discovery of CLR. CLR is one of the PRR receptors found in immune cells that recognize the cell wall of fungi and then trigger a transduction signal that eventually provoke the production of various proinflamatory include IL1β, IL6, TNF α and induce polarization Th17. In the condition of infection the number of innate immune cells increases dramatically, lead to increasing of cytokines produced. Both cytokines and the cells that produce them enter the bloodstream. If there is unbalance level of pro and anti inflammatory cytokine, various inflammatory and/or autoimmune diseases can be occur. Unlike the focal concept infection, where the agent will cause disease if enters the blood vessels, through this concept a fungal infection at epithelium can lead to inflammatory diseases in other part of body without having to go through fungus</em></p><p><em> </em></p><p><strong><em>Keywords:</em></strong><em> C. albicans, CLR, Cytokine, Inflamatory Disease</em></p><p><strong><em> </em></strong></p><strong><em>Correspondence: </em></strong><em>Erna Sulistyani, Department of Oral Medicine, Faculty of Dentistry, Jember Bagian Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Jember, Kalimantan 37 Jember, Email: </em><a href="mailto:erna.sulistyani67@gmail.com"><em>erna.sulistyani67@gmail.com</em></a>
The Effect of Hyperbaric Oxygen Therapy to the Amount of Lymphocytes in Oral Candidiasis Immunosuppressed Model
Authors: Pargaputri Agni Febrina , Andriani Dwi 
Published: July 2019

<p><strong><em> </em></strong></p><p><strong><em>Background: </em></strong><em>Oral candidiasis generally caused by Candida albicans with prevalence of 30-50%. C. Albicans proliferation in the oral cavity was canducted by decreasing immune system of the host. Lymphocytes activation in immune system happened when there is a contact between host cell with cell wall of C. albicans as a result of C. albicans antigen. One of therapy to suppress the Candida infection sistemically is by giving hyperbaric oxygen therapy. <strong>Purpose: </strong>To determine the effects of giving hyperbaric oxygen therapy to the amount of lymphocytes in oral candidiasis immunosuppressed models. <strong>Methods:</strong> This research was post test only control group design. We used 12 wistar rats which were divided into 3 groups(n=4/3): K-(normal/ healthy wistar rats), K+(oral candidiasis immunosuppressed wistar rats), P1(oral candidiasis immunosuppressed wistar rats which were given hyperbaric oxygen therapy 5 days). K+ and P1 groups were immunosuppressed by giving dexamethasone 0,5mg/day/rat orally for 14 days, added with tetrasiklin 1 mg/day/rat. On the 3rd day immunosuppression, the rats were inducted with C.albicans smeared in the dorsum linguae once every two days for 12 days. <strong>Results:</strong> The data were analyzed with one way Anova test and showed significant difference among groups (p&lt;0,05). To show the difference between each groups we used LSD test and showed significant difference (p&lt;0,05) between K+ compared with P1, and K+ compared with K-. <strong>Conclusion:</strong> Hyperbaric oxygen therapy gives effect to the amount of lymphocytes in oral candidiasis immunosuppressed models.</em></p><p><em> </em><strong><em>Keywords:</em></strong><em> Oral candidiasis, immunosuppressed, hyperbaric oxygen therapy, lymphocytes</em></p><p> <strong><em>Correspondence</em></strong><strong><em>: </em></strong><em>Agni Febrina Pargaputri</em><em>, Departmen</em><em>t of</em><em> Oral </em><em>Biology </em><em>F</em><em>aculty of</em><em> </em><em>Dentistry</em><em>, Jl. Arif Rahman Hakim 150, Surabaya, Indonesia. </em><em>Phone:</em><em> 031-5945864, fax: 031-5912191, Email: </em><em><span style="text-decoration: underline;">agni.febrina</span></em><em><span style="text-decoration: underline;">@hangtuah.ac.id</span></em></p><p> </p>
Perbedaan Compressive Strength Scaffold Kombinasi Kitosan dan Ekstrak Aloe Vera dengan Pelarut Air dan Etanol
Authors: Sularsih Sularsih , Widaningsih Widaningsih , Trisnawati Dwi Ayu 
Published: July 2019

<strong><em>Background: </em></strong><em>Scaffold can be use in bone regeneration, but it should have similarities characteristic to a natural bone such as compressive strength that supported the process of growth and development of bone. This research use scaffold that made from chitosan and Aloe vera. Chitosan well-known as <em>osteoconductive</em> material, meanwhile Aloe vera was osteoinductive material. <strong>Purpose: </strong>The aim of this research was to compare compressive strength scaffold combinations of chitosan and Aloe vera extracted water and ethanol. <strong>Methods:</strong> Research design using post test only control group design with 36 scaffolds divided into 6 groups. Group 1 was scaffold Aloe vera extracted water (AVa), group 2 was scaffold Aloe vera extracted ethanol (AVe), group 3 was scaffold combination chitosan and Aloe vera extracted water 1: 1 (k-AVa1), group 4 was the scaffold combination of chitosan and Aloe vera extracted ethanol 1: 1 (k-AVe1), group 5 was scaffold combination of chitosan and Aloe vera extracted water 1: 2 (k-AVa2), and group 6 was scaffold combination of chitosan and Aloe vera ethanol extract 1: 2 (k -AVe2). Compressive strength test used Universal Testing Machine (Shimadzu Autograph–AGS–1kNX and using software Trapezium X). Data were analyzed using One Way ANOVA and Games Howell test. <strong>Results: </strong>The result of compressive strength AVa=1.36 MPa, AVe=1.03 MPa, k-AVa1=0.27 MPa, k-AVe1=0.11 MPa, k-AVa2=0.38 MPa, and k-AVe2=0.29<strong> </strong>MPa<strong>. </strong>All groups have significant differences except AVa &amp; AVe and k-AVa1 &amp; K-AVe2 (p&gt;0,05). <strong>Conclusion: </strong>There was difference between compressive strength scaffold combinations of chitosan and Aloe vera extracted water and ethanol, and the most highest compressive strength is AVa.</em>
Effect of 2% Lignocaine Solution in Pain During Removal of Nasal Pack
Authors: Dhakal Ashish , Shrestha Bikash Lal , Pokharel Monika 
Published: July 2019

Background: Nasal packing is commonly done after septal surgeries. Nonabsorbable nasal pack is used to minimize bleeding from surgery site, support the mucoperichondrial flaps, and minimize the risk of formation of septal hematomas and adhesions. However, these materials cause pain and discomfort in-situ as well as during removal. This study was done to evaluate the effect of 2% lignocaine rehydration of nasal pack on pain during pack removal.
Methods: This prospective study was conducted on 60 patients who had undergone septoplasty. The patients were divided into 2 groups: Lignocaine and Normal saline group, with 30 patients each. In the Lignocaine group, 2.5 ml of 2% of lignocaine was diluted with 2.5 ml of distilled water and was injected into the nasal pack; and in Normal saline group, 5 ml of normal saline was injected into the nasal pack. Nothing was injected to the left nostril, which acted as a control, in both groups. All patients were asked severity of pain during removal of nasal packing by VAS.
Results: In lignocaine group, mean pain score was 3.73 ± 1.63 on lignocaine side and 6.23 ± 1.69 on control side (U=109.5, p<0.001). In Normal saline group, it was 6.5 ± 1.7 on normal saline side and 6.23 ± 1.96 on control side (U=425.5, p=0.711). On comparing VAS between lignocaine and normal saline group, pain was significantly lower in the lignocaine group (U=112.5, p<0.001)
Conclusion: Rehydrating nasal pack with 2% topical lignocaine is a useful method to reduce pain during nasal pack removal.
Impact and Perception of Social Networking Sites on Academic Performance of Medical Students
Authors: Upadhyay Hari Prasad , Sedain Prativa 
Published: July 2019

Background: A social networking site is an online platform that allows users to create a public profile and interact with other users on the website. The emergence of Social Networking Sites has broadened the base of contact, interaction and communication among people living round the globe via internet. Millions of students are logging in to these social networking sites, everyday. That’s why many students have been blaming various social networking sites for their steady decrease in grade point averages and has affected their study time, poor grammar and wrong spellings when socializing on social media as well as diverting their attention from their studies. The objective of this research is to find the impact and perception of social networking sites on academic performance of medical students.
Methods: A descriptive cross-sectional study design conducted among 230 Medical students of MBBS, BPH, Pharmacy and BN Nursing’s students. A well-structured questionnaire was prepared and which were distributed among students using probability sampling technique (random number table).
Results: The response of 230 students was collected by using well structure questionnaire. The mean±SD of students age was 21.87±2.16 years. Majority of the students were in the age group 20-25 years. Majority of them were female by gender and Hindu by religion. They most commonly used social networking site was face book/messenger (48.7%) followed by YouTube (41.3%). The main aim of using these sites is to update with their family, friends and for entertainment. Nearly 60% students told that there are negative effects of using social networking sites. And only 15.6% students used these sites only for academic purpose.
Conclusions: This study revealed that majority of the students used mobile phone as a device and Wi-Fi in their place of residence. The overall perception of students towards social networking sites is positive. Excessive use of these sites decreases their academic performance which conclude that there is Negative relationship between the use of social networking sites and academic performance which in turn negatively affect their academic results.
Thoracoscopic Surgery for Posterior Mediastinal Mass: Our Initial Experience
Authors: Sapkota Ranjan , Sayami Prakash 
Published: July 2019

Background: Thoracoscopic surgery has been increasingly used for a variety of indications. Posterior mediastinal tumors form an important component of a thoracic surgeon’s workload. This report represents a summary of our initial experience in thoracoscopic management of such tumors.
Methods: We retrospectively reviewed the clinical and operative data from records over the study period. We also describe our usual perioperative management and surgical techniques.
Results: A total of 11 patients, 8 being females, were operated during the period of 30 months. Seven were incidental findings, and chest pain was the commonest presentation in symptomatic patients. The mean age of the patients was 38.7 years; mean tumor diameter was 4.4 cm; eight had benign schwannoma, and no patient had a malignant tumor. Mean operative duration was 175.5 min; there were no conversions and no transfusion was required. Mean length of stay in the hospital was 5.6 days. There were no perioperative deaths or major complications. Three minor complications were recorded. Follow-up (4 to 18 months) was uneventful.
Conclusions: Thoracoscopic management of posterior mediastinal tumors is feasible and safe.