bluuebunny/crossref_metadata_2025_split huggingface dataset:
INTEGRASI ILMU-ILMU ALAM DAN ILMU-ILMU SOSIAL DENGAN PEMAHAMAN HADIS NABI: Telaah atas Konsepsi, Aplikasi, dan Implikasi
Authors: Afwadzi Benny 
Published: February 2018

Abstract: This article discusses an integration of natural and social sciences through understanding prophetic ḥadīth(s). It focuses on its conceptions, applications, and implications. The word “integration” is aimed to comprehend the ḥadīth in relation to those two particular sciences. This paper concludes that the conception of ḥadīth integration with the sciences lies on a paradigm shift in the study of ḥadīth. In this concept, ḥadīth(s) are used as material objects that are approached by the natural and social sciences as its formal objects (approach). In practice, four ḥadīth(s) are understood by the natural sciences, and the other four ḥadīth(s) as objects are understood by the social sciences. The understanding of ḥadīth through the natural sciences is textually stronger than that through directly understanding the textual ḥadīth, while the understanding through the social sciences alludes to the emergence of contextual understanding.Abstrak: Tulisan ini mengkaji integrasi ilmu-ilmu alam dan ilmu-ilmu sosial dengan pemahaman hadis Nabi, yang menitiberatkan pada kajian konsepsi, aplikasi, dan implikasi. Integrasi dalam tulisan ini dimaksudkan dengan pemahaman hadis dengan perangkat ilmu-ilmu alam dan ilmu-ilmu sosial. Tulisan ini menyimpulkan bahwa konsepsi integrasi hadis dengan ilmu-ilmu alam dan ilmu-ilmu sosial berpijak pada pergeseran paradigma dalam studi hadis. Dalam konsep ini, hadis berposisi sebagai objek material yang didekati dengan ilmu alam dan ilmu sosial sebagai objek formalnya (pendekatan). Dalam tataran aplikasi, empat hadis dipahami dengan ilmu-ilmu alam dan empat hadis sebagai objek yang dipahami dengan ilmu-ilmu sosial. Implikasi yang ditimbulkan oleh ilmu-ilmu alam adalah pemahaman tekstual yang lebih kuat dibandingkan dengan pemahaman langsung dari teks hadisnya, sedangkan ilmu-ilmu sosial berimplikasi munculnya pemahaman yang kontekstual.
A Green Synthesis of Xanthenone Derivatives in Aqueous Media Using TiO2-CNTs Nanocomposite as an Eco-Friendly and Re-Usable Catalyst
Authors: Samani Amir , Abdolmohammadi Shahrzad , Otaredi-Kashani Asieh 
Published: February 2018

Aim and Objective:
The xanthene (dibenzopyran) framework constitutes the core
structure of many biologically active compounds, that they have been of interest because of their
pharmacological activities like antiviral, antibacterial, anti-inflammatory, and CCR1 antagonist. As
heterogeneous catalysts offer several advantages over homogeneous catalysts, the performance of
reactions on the surface of nanosized heterogeneous salts has received a great deal of interest in
recent years. In the area of nanosized heterogeneous catalysts there is a noticeable range of reactions
that are catalyzed efficiently by TiO2 NPs. Moreover, carbon nanotubes (CNTs) as a support can be
used to obtain nanoparticles with modified morphology, structural, chemical, electrical, and optical
properties. The catalytic activity of titanium dioxide supported on carbon nanotubes has been greatly
improved.

Materials and Methods:
The present methodology focus on the synthesis of 7,7-dimethyl-10-aryl-
6,7,8,10-tetrahydro-9H-[1,3]dioxolo[4,5-b]xanthen-9-ones, through a condensation reaction of
dimedone, aromatic aldehydes and 3,4-methylenedioxyphenol, using a catalytic amount of TiO2-
CNTs nanocomposite (15 mol%) at 80 ˚C in aqueous media, within 60-90 min. The TiO2-CNTs
nanocomposite was also prepared by a known simple sonochemical method.

Results:
A series of 7,7-dimethyl-10-aryl-6,7,8,10-tetrahydro-9H-[1,3]dioxolo[4,5-b]xanthen-9-ones
were successfully synthesized in high yields (92-98%). All synthesized compounds were well
characterized by their satisfactory elemental analyses, IR, 1H and 13C NMR spectroscopy. The
synthesized catalyst was fully characterized by SEM, TEM, XRD, and EDX techniques.

Conclusion:
In summary, this investigation constitutes a novel and efficient route for the synthesis
of 7,7-dimethyl-10-aryl-6,7,8,10-tetrahydro-9H-[1,3]dioxolo[4,5-b]xanthen-9-ones in high yields, by
a three-component reaction of dimedone, aromatic aldehydes and 3,4-methylenedioxyphenol in
water and in the presence of the TiO2-CNTs nanocomposite as a green, effective and recyclable
catalyst. This novel method has the advantages of high yields, mild reaction conditions, short
reaction time, easy work-up, inexpensive reagents and environmentally friendly procedure.
Molecular Docking in Formulation and Development
Authors: Kaur Tejinder , Madgulkar Ashwini , Bhalekar Mangesh , Asgaonkar Kalyani 
Published: February 2018

Background:In pharmaceutical research drug discovery and development process is timeconsuming and expensive. In many cases, it produces incompetent results due to the failure of in vitro and in vivo conventional approaches. Before any new drug is placed in the market it must undergo rigorous testing to get FDA approval. Due to the several limitations imposed by the drug discovery process, in recent times in silico approaches are widely applied in this field. The purpose of this review is to highlight the current molecular docking strategies used in drug discovery and to explore various advances in the field.Methods:In this review we have compiled database after an extensive literature search on docking studies which has found its applications relevant to the field of formulation and development. The papers retrieved were further screened to appraise the quality of work. In depth strategic analysis was carried out to confirm the credibility of the findings.Results:The papers included in this review highlight the promising role of docking studies to overcome the challenges in formulation and development by emphasizing it’s applications to predict drug excipient interactions which in turn assist to increase protein stability; to determine enzyme peptide interactions which maybe further used in drug development studies; to determine the most stable drug inclusion complex; to analyze structure at molecular level that ascertain an increase in solubility, dissolution and in turn the bioavailability of the drug; to design a dosage form that amplify the drug discovery and development process.Conclusion:This review summarizes recent findings of critical role played by molecular docking in the process of drug discovery and development. The application of docking approach will assist to design a dosage form in the most cost effective and time saving manner.
The Protective Effects of Green Tea Catechins in the Management of Neurodegenerative Diseases: A Review
Authors: Farkhondeh Tahereh , Yazdi Hanieh Shaterzadeh , Samarghandian Saeed 
Published: February 2018

Background:The therapeutic strategies to manage neurodegenerative diseases remain limited and it is necessary to discover new agents for their prevention and control. Oxidative stress and inflammation play a main role in the pathogenesis of neurodegenerative diseases. The aim of this study is to review the effects of green tea catechins against the Neurodegenerative Diseases.Methods:In this study, we extensively reviewed all articles on the terms of Green tea, catechins, CNS disorders, and different diseases in PubMed, Science Direct, Scopus, and Google Scholar databases between the years 1990 and 2017.Results:The present study found that catechins, the major flavonoids in green tea, are powerful antioxidants and radical scavengers which possess the potential roles in the management of neurodegenerative diseases. Catechins modulate the cellular and molecular mechanisms through the inflammation-related NF-&amp;#954;B and the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathways.Conclusion:The findings of the present review shows catechins could be effective against neurodegenerative diseases due to their antioxidation and anti-inflammation effects and the involved biochemical pathways including Nrf2 and NF-kB signaling pathways.<P&gt;
VaD - An Integrated Framework for Cognitive Rehabilitation
Authors: Balea Maria , Muresanu Dafin , Alvarez Anton , Homberg Volker , Bajenaru Ovidiu , Guekht Alla , Heiss Wolf-Dieter , Popa Livia , Vester Johannes , Muresanu Ioana , Birle Codruta , Slavoaca Dana 
Published: February 2018

Background & Objective: Vascular dementia is the second most common cause of dementia,
with clinical features that depend on neural substrates affected by the vascular lesions. Like most
neurological disorders, it involves alterations that range from the molecular level to neuronal networks.
Such alterations begin as compensatory mechanisms that reshape every subsystem involved in
the brain's homeostasis. Although there have been recent huge advances in understanding the pathophysiology
of cognitive dysfunction, a suitable therapeutic approach to vascular dementia remains elusive.
Pharmacological interventions have failed to sustainably improve cognitive function, and it is a
well-known fact that there is a need to change the current view for providing neuroprotection and enhancing
neurorecovery after stroke. Studies regarding cognitive training are also faced with the difficulty
of drawing up protocols that can embrace a holistic approach in cognitively impaired patients.

Conclusion:
This review will present a brief synthesis of current results from basic research data and
clinical studies regarding pharmacological and non-pharmacological interventions in vascular dementia
and will offer an integrated view from the perspective of systems biology.
THE URGENCY OF APPLYING DOMESTIC VIOLENCE SCREENING MECHANISM FOR DIVORCE MEDIATION IN RELIGIOUS COURT
Authors: T Tirtawening , Maryam Rini 
Published: February 2018

AbstractThe mediation process in divorce cases is vulnerable to power relation imbalances and domestic violence. Domestic Violence Screening is a set of questions delivered by the mediator to the parties in Religious Court to examine whether domestic violence happens in the marriage. Domestic Violence Screening in mediation is not well known in Indonesia however it has been vastly used in many countries such as USA and Australia. This research tried to explained the benefit of Domestic Violence Screening in divorce mediation in Religious Court and identify whether it can be applied in Indonesia. Screening allows for: a) identification of power relation imbalance and domestic violence; b) domestic violence recording; and c) provide referral services for domestic violence victims. IntisariMediasi perkara perceraian rentan mengalami ketimpangan relasi kuasa dan kekerasan dalam rumah tangga/KDRT. Skrining KDRT (screening domestic violence) merupakan sejumlah daftar pertanyaan yang diajukan oleh mediator kepada para pihak yang berperkara di pengadilan agama untuk memeriksa apakah telah terjadi kekerasan selama ikatan pernikahan. Meskipun skrining KDRT belum dikenal di Indonesia namun telah digunakan secara luas dalam mediasi di berbagai negara. Penelitian ini bertujuan untuk memberikan gambaran sejauh mana manfaat skrining KDRT pada saat mediasi perkara perceraian dan apakah skrining tersebut dapat diterapkan di Indonesia. Keberadaan skrining memudahkan untuk: (a) mengidentifikasi terjadinya ketimpangan relasi kuasa dan kekerasan domestik sebagai faktor penyebab perceraian, (b) melakukan pendataan kasus KDRT, dan (c) memberikan layanan rujukan kepada korban KDRT.
NILAI-NILAI KEARIFAN LOKAL YANG DITERAPKAN DALAM PENGELOLAAN TANAH PARIWISATA SRI GETHUK DI BLEBERAN, PLAYEN, GUNUNG KIDUL
Authors: Sudaryanto Agus 
Published: February 2018

AbstractThe management of the land of Sri Gethuk waterfall in Bleberan Playen Gunungkidul should be by applying local wisdom values locally. The results showed: first, the value of local wisdom used in the management of Srigethuk tourism is the value of innovation, persistence value, the value of togetherness, the value of musyawarah, the value of locality and religious value; secondly, the Solution if there is a conflict of value in the management of Srigethuk tourism is done through compromise, deliberation or wisdom. IntisariPengelolaan tanah wisata air terjun Sri Gethuk di Bleberan Playen Gunungkidul seharusnya dengan menerapkan nilai kearifan lokal setempat. Hasil penelitian menunjukkan: pertama, nilai kearifan lokal yang digunakan dalam pengelolaan wisata Srigethuk adalah nilai inovatif, nilai kegigihan, nilai kebersamaan, nilai musyawarah, nilai lokalitas dan nilai religious; kedua, Solusi jika terjadi benturan nilai dalam pengelolaan wisata Srigethuk dilakukan melalui kompromi, musyawarah atau kebijaksanaan/ kearifan.
PERFIL SANITÁRIO DA FARINHA DE MANDIOCA COMERCIALIZADA EM FEIRA LIVRE
Authors: Santos Juliete de Jesus , Freitas Fernanda , Amor Ana Lucia Moreno , Silva Isabella de Matos Mendes da 
Published: February 2018

Objetivou-se avaliar o perfil sanitário da farinha de mandioca comercializada na feira livre de Santo Antônio de Jesus, Bahia. Foi realizado o diagnóstico das condições higiênico-sanitárias em 19 pontos de venda da farinha de mandioca por meio da aplicação da lista de verificação (check-list) segundo a legislação sanitária vigente. Foi feita a contagem de bolores e leveduras em 19 amostras da farinha de mandioca por meio de semeadura em superfície utilizando o método tradicional de contagem em placas. Ao nível microscópico, foram pesquisados fragmentos de contaminantes nas amostras de farinha de mandioca coletadas. O diagnóstico das condições higiênico-sanitárias revelou que 100% dos pontos de venda de farinha foram classificados como ruins, atendendo apenas a 11,5% dos itens estabelecidos na lista. Na análise microbiológica a população de bolores e leveduras variou entre <1,0 x 10² a 8,0 x 104 UFC/g, constatando uma população acima de 1,0 x 103 UFC/g em 73,7% das amostras. Foram identificados fios de cabelos, fragmentos de inseto, fragmentos de aranha, pedaços de madeira e pelo de animal na análise microscópica. Dessa forma, são necessários investimentos do poder público municipal na estrutura física do galpão de mandioca e ações educativas que envolvam manipuladores e consumidores da farinha de mandioca, garantindo a saúde da população.
The Impact of Fair Value Measurement for Bank Assets on Information Asymmetry and the Moderating Effect of Own Credit Risk Gains and Losses
Authors: Fontes Joana C. , Panaretou Argyro , Peasnell Kenneth V. 
Published: February 2018

ABSTRACT
We examine whether the use of fair value measurement (FVM) for bank assets reduces information asymmetry among equity investors (bid-ask spread) and how this is affected by the recognition of own credit risk gains and losses (OCR). Our findings show that FVM of assets is associated with noticeably lower information asymmetry, and that this reduction is more than twice as large when banks also recognize OCR. In addition, we find that the bid-ask spread is incrementally lower for banks that provide more detailed narrative disclosures on OCR. The findings also indicate that the effects of asset FVM and OCR recognition on the bid-ask spread do not simply capture the differences in the characteristics of the banks and the quality of their information environments.
Data Availability: All data are available from public sources.
POTENSI PEMANFATAN SAMPAH DI PASAR LEUWILIANG, CIGUDEG DAN JASINGA KABUPATEN BOGOR MELALUI PENGOLAHAN SAMPAH TERPADU
Authors: Ratnaningsih Ratnaningsih , Purwaningrum Pramiati , Haryanti Fajriani Widya 
Published: February 2018

Pasar traditional mempunyai kontribusi yang besar sebagai penghasil sampah, demikian juga Pasar Leuwiliang (luas 21.714 m2), Cigudeg (luas 11.000 m2) dan Jasinga (luas 18 m2) yang berada di Kabupaten Bogor. Tujuan dari penelitian ini adalah mengetahui potensi sampah untuk dimanfaatkan kembali dan merancang pengelolaan sampah terpadu sesuai dengan karakteristik dan komposisi sampahnya. Metode pengambilan sampel sampah berdasarkan SNI 19-3964-1994. Hasil penelitian diperoleh timbulan sampah Pasar Leuwiliang sebesar 46,36 m3/hari, Pasar Cigudeg 57,73 m3/hari dan Pasar Jasinga 120,65 m3/hari. Laju timbulan sampah Pasar Leuwiliang sebesar 184,08 liter/m2/hari, Pasar Cigudeg sebesar 262,79 liter/m2/hari dan Pasar Jasinga sebesar 311,118 liter/m2/hari. Rata-rata komposisi sampah organik ketiga pasar tersebut sebesar 71% dan 29% non oganik. Perencanaan teknis pengelolaan sampah terdiri dari pemilahan, pewadahan, pengumpulan sampah, pengangkutan sampah dan pengolahan di Tempat Pengolahan Sampah Terpadu (TPST). Alat pengumpul direncanakan berupa gerobak dengan kapasitas 1 m3 sedangkan alat angkut direncanakan berupa dump truck dengan kapasitas 10 m3. Lokasi TPST direncanakan di Pasar Leuwiliang seluas 826 m2, dengan kapasitas ± 100 m3/hari yang akan melayani sampah dari Pasar Leuwiliang, Pasar Cigudeg dan Pasar Jasinga. TPST tersebut direncanakan akan memiliki 6 bak pengomposan. Sampah organik yang akan diolah di TPST sekitar 70% dari total timbulan sampah sedangkan sisanya akan dipilah menjadi dua bagian yaitu sampah non organik yang akan dijual ke lapak dan residu akan diangkut ke TPA Galuga Bogor. Potensi sampah yang dapat dimanfaatkan kembali dari ketiga pasar tersebut mencapai 88,94%-99,44%. Total kompos yang dihasilkan sebesar 1047,62 kg/hari dan total sampah non organik yang akan dijual ke pelapak sampah non organik adalah sebesar 708,95 kg/kg. Perencanaan TPST diharapkan dapat menjadi solusi dari masalah persampahan dan dapat memberi manfaat bagi masyarakat pasar maupun masyarakat sekitar pasar
Reseñas
Authors: Carabantes Isabel , Díaz Navarro Epicteto 
Published: February 2018

Naval, María Ángeles y Carandel, Zoraida (eds.) (2016), La transición sentimental. Literatura y cultura en España desde los años setenta. Madrid: Visor. Biblioteca Filológica Hispana Nº 184.
García, Carlos Javier y Sobejano, Gonzalo (eds.) (2016), Luis Goytisolo, Antagonía, Madrid: Cátedra.
El uso de la Tecnología en ambientes educativos. Análisis de su inclusión un contexto formativo contemporáneo (The use of technology in educational environments. Analysis of their inclusion in a formative contemporary context)
Authors: Cortés Lozano Astrid Ximena , Vásquez Rizo Fredy Eduardo 
Published: February 2018

Este artículo presenta una reflexión relacionada con el impacto de la tecnología en ambientes educativos. Se ha realizado o un análisis desde diferentes escenario, considerando la posición de los distintos protagonistas (maestro, alumnos, grupos, instituciones), que participan en el proceso educativo, resaltando su importancia, resaltando su importancia en la sociedad del conocimiento. Lo anterior, con la intención de hacer un llamado de atención para que no siga acrecentando la actual brecha digital que separa tan marcadamente los países del llamado primer mundo. Desde esta perspectiva se plantean unas ideas y se proponen soluciones al problema planteado.
La paradoja de la educación y la política pública: limitaciones en la política pública para generar una educación inclusiva y la necesidad de la educación para la inclusión social (The paradox of education and public policy)
Authors: Baquero Micrán Iván Rodrigo 
Published: February 2018

Abordar el tema de inclusión social en el contexto actual de nuestro país, en el cual se está llevando a cabo el proceso de paz, resulta complejo y a la vez necesario; complejo debido a varios factores entre los cuales se pueden señalar la polarización, la falta de identidad y fines comunes, la cultura de la indiferencia y el descarte, el individualismo, el facilismo y los fundamentalismos ideológicos; necesario porque si se analiza en profundidad la historia del conflicto en nuestro país ha estado enmarcado en las condiciones de injusticia, desigualdad, marginalidad y falta de políticas que permitan un auténtico desarrollo sostenible e incluyente y si se quiere alcanzar la paz, no bastará con la firma de un documento sino con un cambio real en las políticas públicas y en la mentalidad de cada colombiano como condición de posibilidad de la misma.
Desarrollo de competencias de investigación en estudiantes de educación superior con la mediación de herramientas de m-Learning & e-Learning (Development of research competencies in higher education students)
Authors: Aguirre León César Augusto 
Published: February 2018

La presente investigación, pretende determinar la posibilidad de potenciar las competencias en investigación en estudiantes de educación superior, para ello realiza un acercamiento a la temática propuesta desde la perspectiva de estudios recientes y posteriormente reseña de manera específica las didácticas para adultos presentes en la andragogía. Luego, explora el concepto de competencia, llegando a su uso específico en investigación. Con respecto a los recursos aportados por las tecnologías de la información y la comunicación (TIC) expone su origen y características generales, muestra los alcances de la enseñanza en la era digital y los cambios que se deben dar en la educación a partir de las nuevas herramientas didácticas disponibles. Luego, se exponen las implicaciones puntuales de los términos e-Learning y m-Learning, como antecedente para presentar las experiencias en este tema en un grupo de 11 Instituciones de educación superior colombianas, el análisis de los avances realizados por parte de los estudiantes de la Corporación Universitaria Minuto de Dios Vicerrectoría Regional Bogotá Sur y el estudio 46 recursos web y aplicaciones que permiten adelantar procesos de aprendizaje en el ámbito de la investigación.
AN ANALYSIS OF HUMOR IN J.M BARRIE’S PLAY “THE OLD LADY SHOWS HER MEDALS” ON EFL LITERATURE CLASS
Authors: Annury Muhammad Nafi 
Published: February 2018

People tend to find beauty in their life. They create such as painting, dance, music, literature and etc. As one of arts forms, literature is different from other forms of art. It is work writing. People read it for pleasure. They do it in order to know about human life, including its problems, customs, habits, ambition and desires. The data of the study was taken by some following procedures: 1) quoting, means that the writer quoted the dialogue and the stage directions of the play which contains humorous expressions. 2) classifying, means that the writer classified the data into the five groups according to the types of humor such as “wit”, “sarcasm”, “satire”, “irony”, and “repartee”. For the analysis the writer used aspects of drama or play to analyzing it. The aspects of play which is used in analyzing the data are synopsis, characterization (how the characters are described and how they behave), and the language (how the characters speak and how humor is reflected in the play). The writer attempted to understand the meaning of the play and how the expressions of humor employed in the play. He identified sentences that represent characters’ feeling and expressions. Last but not least, the writer used descriptive analysis method. Since the descriptive method is used in the literal sense of describing situations or events. The writer used the descriptive analysis to report the result of the analysis from the data taken. In this case he described expressions of humor which are found in the play