bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Outcomes of a Pharmacist-Run, Outpatient Insulin Titration Telepharmacy Service
Authors: Deas Crystal , Stockton Katharine 
Published: May 2019

Purpose: Diabetes can pose a significant disease burden for patients and is often challenging to manage in underserved patient populations with limited access to care. A pilot study was conducted to determine the impact of a pharmacist-run insulin titration service, provided via telephone, to patients of a local ambulatory care clinic with a large medically, underserved patient population. The pilot service was implemented in Spring 2018 at Cooper Green Mercy Health Services (CGMHS) and was provided by an affiliate clinical pharmacist who is also on faculty at Samford University’s McWhorter School of Pharmacy. Patients who received care within the CGMHS diabetes clinic were eligible for referral to the service. The service was provided via a collaborative practice agreement. The purpose of this study was to evaluate and compare clinical outcomes of patients who received the telepharmacy service versus the standard of care. Standard of care was defined as patients whose insulin therapy was managed solely by the primary care provider or by a diabetes clinic provider, without clinical pharmacist involvement in the patient’s care.
Methods: This manuscript presents the results of a retrospective chart review conducted at CGMHS of patients, ages 19 or older, with a documented diagnosis of type 1 or type 2 diabetes who received care during the timeframe of February 2018 through September 2018 – the initial months of the pilot telepharmacy service.
Results: Sixty-seven patients met criteria for inclusion in the analysis - 16 managed in the telepharmacy service, 28 in diabetes clinic, and 23 in primary care. Patients in the telepharmacy group achieved a mean A1c change of -1.14% compared with -0.88% in the diabetes clinic group and +0.21% in the primary care group (p=0.061). In the telepharmacy group, 43.75% of patients experienced at least a 1% reduction in A1c from baseline compared with 35.71% in the diabetes clinic group and 26.09% in primary care (p=0.51).
Conclusion: Integration of the clinical pharmacy services for insulin titration positively affected patients’ degree of glucose control. Although no statistically significant reductions in A1c were observed in this study, it should be noted that pharmacist intervention was associated with a modestly higher percent A1c reduction from baseline vs. the standard of care. The pharmacist-run service produced changes in clinical outcomes that numerically exceeded those experienced by patients receiving specialty care, in the diabetes clinic, and within primary care. As a result of this study, the pilot program has remained in effect and is in the initial stages of expansion of the consult service to eligible primary care patients.

Article Type: Original Research
Deep Learning Model for Predicting Solvation Free Energies in Generic Organic Solvents
Authors: Lim Hyuntae , Jung Younjoon 
Published: May 2019

Prediction of aqueous solubilities or hydration free energies is an extensively studied area in machine learning applications on chemistry since water is the sole solvent in the living system. However, for non-aqueous solutions, few machine learning studies have been undertaken so far despite the fact that the solvation mechanism plays an important role in various chemical reactions. Here, we introduce a novel, machine-learning based quantitative structure-property prediction method which predicts solvation free energies for various organic solute and solvent systems.A novelty of our method involves two separate solvent and solute encoder networks that can quantify structural features of given compounds via word embedding and recurrent layers, with the attention mechanism which extracts important substructures from outputs of recurrent neural networks. As a result, the predictor network calculates solvation free energy of a given mixture using features from encoders. With results obtained from extensive calculations on 2495 solute-solvent mixtures, we demonstrate that our methodology outperforms both ab initio and MD solvation model in terms of estimation error for solvation energy.
Rousseau e Voltaire: duas perspectivas para a história moderna
Authors: Rufinoni Priscila Rossinetti 
Published: May 2019

Este artigo procura pensar qual a importância da noção de “liberdade” para o conceito de história em Rousseau e Voltaire. Em ambas as perspectivas de abordagem, a história moderna segue uma norma teleológica ou há um espaço para a ação política?
Women and Communist China Under Mau Zedong:
Authors: Wielink Michael 
Published: May 2019

The mid twentieth century was a tumultuous and transformative period in the history of China. Mao Zedong and the Communist Party seized control and established the People’s Republic of China on October 1, 1949, which was the culmination of over two decades of civil and international war. Mao Zedong’s famed political slogan: “Women Hold Up Half The Sky[1],” was powerful rhetoric, with the apparent emphasis on gender equality and inferred concepts of equality and sameness. Women did not achieve equality with men, nor did they attain egalitarian self-determination nor social autonomy. Nevertheless, when Chinese Communism under Chairman Mao is analyzed we discover women, both rural and urban, were able to challenge social, cultural, and economic gender stratification. Mao envisaged “women’s equality” as a dynamic force with an indelible power to help build a Chinese Communist State. This essay illustrates the ways in which women inextricably worked within Mao’s Communist nation building efforts to slowly erode gender inequalities. Yet despite the inability of full gender equality to be realized, this era allowed women to experience a broad range of experiences which contained the seeds of change toward breaking down gender inequality. Ultimately, Chinese women under Mao created a more fertile environment so the seeds of equality may continue to grow, perhaps bearing fruit of full “gender equality” in the future.

[1] Xin Huang, The Gender Legacy of the Mao Era: Women's Life Stories in Contemporary China (Albany: State University of New York Press, 2018): 14.
Quelle pertinence des "récits d’enfants" pour une recherche "avec" eux ?
Authors: Lani-Bayle Martine 
Published: May 2019

Que font, que nous font les démarches de récit de vie et d’expérience ? Pourquoi nous intéressent-ils ? Autour de telles interrogations, j’ai questionné la voie narrative ouverte par la perspective clinique que j’ai qualifiée de « dialogique» et qui s’inscrit dans la lignée du courant des histoires de vie. Constatant alors qu’elle était surtout proposée ou pratiquée par des adultes, j’ai impulsé une recherche recueillant des récits d’enfants à propos de leur scolarité, recherche qui s’est développée au Brésil et en Colombie notamment sous l’égide de Maria PASSEGGI. Ces travaux montrent ce dont les enfants sont capables et ce qu’ils peuvent attendre de leurs propres capacités narratives ; et, en écho, ce que nous pouvons en attendre, tant en recherche qu’en éducation. C’est ce que je propose de présenter ici.
PROFIL KEMAMPUAN PENALARAN MATEMATIS DALAM PEMECAHAN MASALAH PADA MAHASISWA CALON GURU MATEMATIKA
Authors: Zuhri Muhammad Saifuddin , Purwosetiyono FX. Didik 
Published: May 2019

NCTM (2000) menetapkan 5 keterampilan proses yang perlu dimiliki siswa dalam pembelajaran matematika yaitu: (1) pemecahan masalah (problem solving); (2) Penalaran dan pembuktian (reasoning and proof); (3) Komunikasi (communication); (4) Koneksi (connection); dan (5) Representasi (representation). Berdasarkan 5 keterampilan proses di atas, penalaran merupakan salah satu keterampilan yang memegang peranan penting. Tujuan penelitian ini adalah untuk mendeskripsikan profil profil kemampuan penalaran matematis dalam pemecahan masalah pada mahasiswa calon guru matematika. Jenis penelitian ini adalah penelitian kualitatif deskriptif karena mendeskripsikan bagaimana profil kemampuan penalaran dalam pemecahan masalah pada mahasiswa calon guru matematika melalui jawaban yang diberikan siswa terhadap tes tertulis serta wawancara. Subjek yang akan dijadikan penelitian ini adalah mahasiswa calon guru matematika Program Studi Pendidikan Matematika Universtias PGRI Semarang. Pemilihan subjek pada penelitian ini menggunakan teknik purposive sampling. Pengumpulan data dilakukan dengan teknik tes tertulis dan wawancara. Analisis data dilakukan berdasarkan data hasil tes tertulis dan data hasil wawancara. Kemudian dilakukan triangulasi metode untuk menghasilkan data dari subjek penelitian yang valid. Hasil dari penelitian ini adalah Subjek dengan gender laki-laki memiliki kemampuan penalaran matematis sebagai berikut: menyajikan pernyataan secara lisan, tertulis, tanpa menggunakan gambar, mampu membuat dugaan bahwa untuk mengetahui waktu yang diperlukan kedua mobil berpapasan adalah dengan menjumlahkan kecepatan kedua mobil, mampu menjelaskan dengan menggunakan model, tetapi subyek tidak melakukan koreksi terhadap jawabannya. Subjek dengan gender perempuan memiliki kemampuan penalaran matematis sebagai berikut: mengidentifikasi fakta dan masalah yang diketahui dalam soal tersebut dengan jelas dan logis, subjek juga mengilustrasikan permasalahan menggunakan gambar, subyek mampu memilih konsep dan aturan yang akan digunakan dalam penyelesaian masalah secara tepat, Subjek melaksanakan rencana yaitu dengan mengalikan kecepatan mobil A dengan waktu (t) tertentu dijumlahkan dengan kecepatan mobil B dengan waktu (t) tertentu., dan subyek tidak melakukan koreksi terhadap jawabannya, karena telah yakin dengan jawaban tersebut.
Evaluación de la técnica quirúrgica "curetaje" axilar para el tratamiento de la hiperhidrosis axilar, fase retrospectiva
Authors: Hernández Claudia Andrea , Gómez Luz Marina , Londoño Ángela , Mendoza Natalia 
Published: May 2019

Introducción. La hiperhidrosis axilar es una condición relativamente frecuente y de difícil manejo, que afecta en forma negativa la calidad de vida del paciente y origina estigmas sociales ya que interfiere con las actividades de la vida diaria. El manejo tradicional de la hiperhidrosis axilar se basa en el uso de preparados tópicos. Como terapias de segunda línea se encuentra la toxina botulínica y diversas técnicas quirúrgicas de destrucción local de las glándulas sudoríparas y la simpatectomía torácica. La técnica quirúrgica de “curetaje” (curetagge) axilar, utilizada en el Servicio de Dermatología de la Universidad Pontificia Bolivariana se propone como una opción para aquellos pacientes que no responden al manejo conservador.Objetivo. Evaluar una técnica quirúrgica llevada a cabo en la Clínica Universitaria Bolivariana y en la Clínica SOMA para el tratamiento de la hiperhidrosis axilar.Metodología. Se trata de un estudio descriptivo, realizado en dos fases: retrospectiva y prospectiva con seguimiento al mes y al año. En este manuscrito se presentan los resultados retrospectivos.Resultados. Se incluyeron 9 pacientes en la fase retrospectiva del estudio, con 18 unidades quirúrgicas. Todos los pacientes habían recibido algún tipo de tratamiento previo. La seriedad de la enfermedad antes de la cirugía era grave en todos los pacientes; al mes de la cirugía era leve en cuatro pacientes y moderada en 5; al año de la cirugía, era leve en dos pacientes y moderada en siete. Siete pacientes consideraron leve el dolor posquirúrgico y hubo una baja tasa de complicaciones.Conclusión. La técnica quirúrgica propuesta para el manejo de la hiperhidrosis axilar es efectiva, con bajo porcentaje de complicaciones, la cual puede ser recomendada como segunda línea de tratamiento para pacientes que no respondan al manejo conservador.
Evaluación de una técnica quirúrgica para el tratamiento de la onicocriptosis en pacientes atendidos en la Clínica Universitaria Bolivariana y Clínica Soma, de enero de 1998 a diciembre de 2010
Authors: Montes Ana Milena , Gómez Luz Marina , Londoño Ángela , Arias Yuliana , Martínez Edna 
Published: May 2019

La onicocriptosis es una condición común, recurrente y dolorosa, que genera incapacidad prolongada en los pacientes afectados. Existen diversas técnicas quirúrgicas para abordar este problema y hasta el día de hoy ninguna ha sido estandarizada.Objetivo. Evaluar una técnica quirúrgica para el tratamiento de la onicocriptosis.Metodología. Es un estudio descriptivo realizado en dos fases: una retrospectiva, con los pacientes operados desde enero de 1998 hasta mayo de 2009, y una prospectiva, de junio 2009 a diciembre 2010, con seguimiento a seis meses. Se incluyeron los pacientes recolectados en la Clínica Universitaria Bolivariana y la Clínica SOMA.Resultados. Se evaluaron 57 pacientes: 45 en la fase retrospectiva y 12 en la prospectiva. Se hizo un análisis por unidad quirúrgica y se obtuvo un total de 92 procedimientos en la fase retrospectiva y, de 31, en la prospectiva. La recaída de la onicocriptosis, en el grupo retrospectivo, fue de 3,3 % (3/92). Sus principales complicaciones fueron la presencia de espícula ungular (3,3 %) y la disestesia en el sitio operatorio (3,3 %). En la fase prospectiva, no se observaron recaídas (0/31). Se presentó infección en dos sitios quirúrgicos (6,5 %) y onicólisis, en la fase inicial del posoperatorio, en 19,4 % (6/31). Todos los pacientes, a excepción de los que presentaron recaída en la fase retrospectiva, relataron mejoría notable de los síntomas y satisfacción con el resultado estético y funcional.Conclusión. La técnica quirúrgica propuesta, usada por más de 10 años, es efectiva, con bajo porcentaje de recaídas y pocas complicaciones.
Yöneticilerin Demokratik-Katılımcı Yönetim Tarzlarının Çalışanların İç Girişimcilik Eğilimlerine Etkisi
Authors: ŞAHİN YARBAĞ Pelin 
Published: May 2019

Araştırmanın amacı,
demokratik-katılımcı yönetim tarzının çalışanların iç girişimcilik eğilimleri
üzerindeki etkisini araştırmaktır. Havacılık sektöründe çalışan 136 çalışanın
katılımıyla anket yapılmıştır. Anket verileri çoklu regresyon analizi
kullanılarak analiz edilmiştir. İç girişimcilik ölçeğinin ve
demokratik-katılımcı yönetim tarzı
ölçeğinin güvenilirlikleri yüksek bulunmuştur (Cronbach’s alpha= .915 ve
.942). Regresyon analizinin sonuçlarına göre demokratik-katılımcı yönetim
tarzının iç girişimciliğin proaktiflik boyutu üzerinde istatistiksel olarak
anlamlı, pozitif ve yüksek düzeyde etkisi bulunmaktadır (p&lt;.001). Özerklik
ve risk alma boyutları üzerinde anlamlı bir etki bulunmamaktadır.
Schopenhauer ve Nietzsche Nihilizmi Sarkacında Dövüş Kulübü Filminin Çözümlemesi
Authors: ATEŞ Cenk , SERARSLAN Meral 
Published: May 2019

Düşünce tarihinde insanlar
arasındaki yapı farkını gözetmeksizin tekil eylemlere indirgenen insan
özgürlüğü problemi, Schopenhauer ve Nietzsche’yle birlikte insandan, bütünlüklü
olarak kişiye evrilmiştir. İki düşünür arasındaki bu fikir birliği, özgürlüğe ulaşmada
izlenecek yol bakımından farklılaşır. Görünenin ardındaki gerçekliği
kavrayarak, istemeyi reddeden Schopenhauer’ın özgür ideal insanı, kaçınılmaz
olarak nihilizme ulaşır. Nietzsche içinse ideal insan hakim değerleri
yoksayarak, yolunu mutlaka nihilizmden geçiren ancak bu noktayı aşarak yeni
değerler yaratabilen insandır. Söz konusu görüş ayrılığı Nietzsche’de, yaşamı
değerden düşüren pasif nihilizmle; yaşamı değil; yaşamın hakim moral
anlayışıyla yorumlanmasını reddeden aktif nihilizm ekseninde şekillenir.
Nihilizme yönelik bu yönlü bir sınıflandırma, istemeyi susturmak anlamında
Schopenhuerci nihilizmle, istemeyi susturan değerleri yıkmakla özdeşleşen,
Nietzscheci aktif nihilizmi iki zıt kutba yerleştirir. Schopenhauer’da nihai nokta olarak değerlendirilen
‘hayır’ ile, Nietzsche’de büyük bir ‘evet’in ön koşulu olarak ifade edilen
‘hayır’,farklı amaçlara hizmet etseler de her iki filozof tarafından olumlanır.

Nihilizm temelli bu görüş
ayrılığını, yönetmenliğini David Fincher’in üstlendiği 1999 yapımı Dövüş Kulübü
filminde görmek mümkündür. Farklı okumalara açık olan film, başkarakter
Jack’in, üstbenin emirleri doğrultusunda yaşadığı dünyaya ilişkin usanmışlığına
anlam arayışını konu edinir. Keskin bir kapitalizm eleştirisi sunan film, hakim
değerlerin yarattığı özgürlük yanılsamasını kırarak, kişinin kendi olma
serüvenini toplumsal değerlerin eylemsel düzeyde reddedilmesiyle ele alır.
Özgürlüğü, kişisel isteme ve eylemle açıklama çabasındaki Dövüş Kulübü, son
sahnesinde Jack’ın, özgürlüğünü simgeleyen
Tyler’ı öldürmesiyle, büyük bir paradoks yaratır. Bu bağlamda çalışma, Dövüş
Kulübü filmini Schopenhauer ve Nietzsche’nin nihilizme yükledikleri farklı
anlamlandırmalar çerçevesinde analiz etmeyi amaçlamaktadır. https://orcid.org/0000-0002-0209-4026
Accuracy of GRK-2200T Auto-refkeratometer in Subjective Acceptance for Refractive Errors
Authors: Adhikari Bishwa Nath , Gautam Pramod Sharma , Upadhyay Shishu , Prakash Uday Chandra 
Published: May 2019

Introduction: Globally, the most common cause for diminution of vision is refractive errors and the number of patients with refractive errors is increasing day by day. The Auto-refraction (AR) is quick and patient friendly procedure as compared to retinoscopy and subjective refraction in finding out refractive errors. Hence, the accuracy of Auto-refractometer in terms of subjective acceptance (SA) should be taken into account before prescribing optical correction based on findings of that particular model of Auto-refractometer. So, this study is directed towards analysis of the accuracy of GRK-2200T Auto-retieratometer in terms of acceptance by comparing findings of AR with that of SC.
Objectives: The aim of this study was to assess the refractive status of patient's eyes using auto refractometer (GRK-2200T auto-retierato meter) and to estimate the agreement of it in terms of accuracy in acceptance of subjective correction by the patient.
Methodology: A hospital based prospective comparative study conducted on 226 eyes of 113 patients who visited out-patient department (OPD) of Ophthalmology at Nobel Medical College and Teaching Hospital (NoMCTH), Biratnagar diagnosed with Myopia, Hyperopia and Astigmatism. Duration of study was 4 months from 2nd October, 2018 to 2nd February, 2019. All data thus collected was subjected to statistical analysis by using SPSS version 22.
Result The mean age of the study subjects was 26.91±7.79 years with male to female ratio of 0.47. When spherical power, cylindrical power and the axis are taken into consideration together, only 13.3% of the total tested eyes subjectively accepted the AR values unchanged. On subjective correction, 32.7% of the tested eyes accepted spherical power while 46.5% accepted cylindrical power and 50.9% accepted axis of AR unchanged. About 52.2% of the total eyes examined fall within the deviation of spherical equivalent (SE) of ±o.25D and up to 67.3% of them fall within the deviation of ±o.50D.
Conclusion The auto refraction by GRK-2200T auto-retieratometer was found to be satisfactory for a preliminary refraction but not satisfactory as substitutes for conventional subjective refraction. However, auto refraction values obtained by GRK-2200T auto-retieratometer could be important in order to accurately prescribe the cylindrical power as well as its axis than the spherical component.
Incidence of Acute Renal Failure in Full Term Neonates with Birth Asphyxia
Authors: Jha Chandra Bhushan , Tamrakar Akhil 
Published: May 2019

Introduction: Birth asphyxia is an eventuality having far reaching consequences in the neonatal period. Hypoxia and ischemia can cause damage to almost every tissue and organ in the body and various target organs involved. Renal insult is a recognized complication of birth asphyxia and carries a poor prognosis. Timely detection of renal dysfunction and appropriate management may favorably alter the prognosis in many neonates with birth asphyxia.
Objective: The present study was done to find out the incidence of acute renal failure in the full term neonates with birth asphyxia.
Methodology: A cross sectional study was conducted at Birat Medical College Teaching Hospital, Morang, Nepal from 1st September 2017 to 28th February 2018. Fifty full term neonates born with Apgar score of <6 at 5 minutes and fulfilling inclusion criteria were enrolled in the study. Asphyxiated neonates having Serum creatinine >1.5gm/dl or urine output<1ml/kg/hr were labeled as cases of Acute Renal Failure. Blood sample for serum creatinine was collected at 24hrs, 48 hrs and 72 hrs of life.
Results A total of 50 term asphyxiated neonates were enrolled in the present study. Among them 54% and 46% were males and females respectively with male to female ratio of 1.2:1. In the present study 62% of cases developed acute renal failure in either of the first three days of life with mean urine output 1.02±0.27ml/kg/hr and mean serum creatinine of 1.49±0.32 mg/dL. The incidence of oliguric renal failure was 52% and non oliguric renal failure was 48%.The association between serum creatinine and urine output was statistically significant.
Conclusion: In the present study birth asphyxia has been an important cause of neonatal acute renal injury, revealing 31 (62%) cases. Monitoring urine output and serum creatinine has helped in detecting the asphyxiated neonates with acute renal injury in the early stage.
Study on the Synergism of Binary Surfactant Mixtures containing N-lauroyl-N-methyl Taurine Sodium
Authors: Meng Fang , Xu Hujun , Chen Xiuying 
Published: May 2019

AbstractThe surface tension of the two mixed systems had been investigated in 0.1 M NaCl solution at 298.15 K respectively, including the surface tension of the anionic surfactant N-lauroyl-N-methyl taurine sodium (SDMT) and of the cationic surfactant dodecyltrimethylammonium chloride (DTAC), and zwitterionic surfactant dodecyl betaine (BS-12). The chemical surface properties of the two mixed systems were studied and the regular solution theory was applied to the two mixed systems. The results showed that the binary surfactant mixtures of SDMT/DTAC and SDMT/BS-12 exhibited synergism in surface tension reduction effectiveness, surface tension reduction efficiency and the mixed micelle formation according to β values. It was also found that the results calculated by this theory agreed well with the experimental values.