bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible migratory choices of Cory’s shearwaters are not driven by shifts in prevailing air currents
Authors: Dell’Ariccia Gaia , Benhamou Simon , Dias Maria P. , Granadeiro José P. , Sudre Joël , Catry Paulo , Bonadonna Francesco 
Published: February 2018

AbstractWind conditions strongly affect migratory costs and shape flyways and detours for many birds, especially soaring birds. However, whether winds also influence individual variability in migratory choices is an unexplored question. Cory’s shearwaters (Calonectris borealis) exhibit migratory flexibility, changing non-breeding destination across the Atlantic Ocean within and between years. Here, we investigated how wind dynamics affect the spatiotemporal migratory behaviour and whether they influence individual choices of non-breeding destination. We analysed 168 GLS tracks of migratory Cory’s shearwaters over five years in relation to concurrent wind data. We found no evidence for an association of the use of specific paths or destinations with particular wind conditions. Our results suggest that shearwaters deliberately choose their non-breeding destination, even when the choice entails longer distances and higher energetic costs for displacement due to unfavourable wind conditions en route. Favourable winds trigger migration only when directed towards specific areas but not to others. Despite their dependence on wind for dynamic soaring, Cory’s shearwaters show a high individuality in migratory behaviour that cannot be explained by individual birds encountering different meteorological conditions at departure or during migratory movements.
Dynamical complexity and computation in recurrent neural networks beyond their fixed point
Authors: Marquez Bicky A. , Larger Laurent , Jacquot Maxime , Chembo Yanne K. , Brunner Daniel 
Published: February 2018

AbstractSpontaneous activity found in neural networks usually results in a reduction of computational performance. As a consequence, artificial neural networks are often operated at the edge of chaos, where the network is stable yet highly susceptible to input information. Surprisingly, regular spontaneous dynamics in Neural Networks beyond their resting state possess a high degree of spatio-temporal synchronization, a situation that can also be found in biological neural networks. Characterizing information preservation via complexity indices, we show how spatial synchronization allows rRNNs to reduce the negative impact of regular spontaneous dynamics on their computational performance.
Long non-coding RNA AC026166.2-001 inhibits cell proliferation and migration in laryngeal squamous cell carcinoma by regulating the miR-24-3p/p27 axis
Authors: Shen Zhisen , Hao Wenjuan , Zhou Chongchang , Deng Hongxia , Ye Dong , Li Qun , Lin Lexi , Cao Bing , Guo Junming 
Published: February 2018

AbstractLong non-coding RNA (lncRNA) AC026166.2-001 was found to be down-regulated in laryngeal squamous cell carcinoma (LSCC) tissues and metastatic neck lymph nodes. Decreased AC026166.2-001 was associated with poorer prognosis and may act as a novel biomarker for LSCC patients. In this study, AC026166.2–001 was overexpressed by a lentivirus vector and down-regulated by a small interfering RNA (siRNA). The results of real-time cell analysis (RTCA) and a plate colony formation assay showed that AC026166.2–001 inhibited LSCC cell proliferation and the clone-forming capacity. Cell cycle distribution and related protein changes were measured by flow cytometry. AC026166.2–001 arrested the cell cycle at the G1 phase and induced apoptosis. In addition, AC026166.2–001 decreased cell migration as measured by wound healing assays and transwell migration assays. Moreover, luciferase reporter assay and Western blotting results suggested that AC026166.2–001 acts as a sponge of miR-24-3p and regulates the expression of p27 and cyclin D1. The in vivo results showed that AC026166.2–001 significantly suppressed the growth of LSCC xenografts and promoted apoptosis. We validated the molecular mechanisms underlying AC026166.2–001 in LSCC. This is the first report of AC026166.2–001 acting as a tumor suppressor in LSCC by regulating the miR-24-3p/p27 axis.
Enhanced Biological Response of AVS-Functionalized Ti-6Al-4V Alloy through Covalent Immobilization of Collagen
Authors: Rezvanian Parsa , Daza Rafael , López Patricia A. , Ramos Milagros , González-Nieto Daniel , Elices Manuel , Guinea Gustavo V. , Pérez-Rigueiro José 
Published: February 2018

AbstractThis study presents the development of an efficient procedure for covalently immobilizing collagen molecules on AVS-functionalized Ti-6Al-4V samples, and the assessment of the survival and proliferation of cells cultured on these substrates. Activated Vapor Silanization (AVS) is a versatile functionalization technique that allows obtaining a high density of active amine groups on the surface. A procedure is presented to covalently bind collagen to the functional layer using EDC/NHS as cross-linker. The covalently bound collagen proteins are characterized by fluorescence microscopy and atomic force microscopy and their stability is tested. The effect of the cross-linker concentration on the process is assessed. The concentration of the cross-linker is optimized and a reliable cleaning protocol is developed for the removal of the excess of carbodiimide from the samples. The results demonstrate that the covalent immobilization of collagen type I on Ti-6Al-4V substrates, using the optimized protocol, increases the number of viable cells present on the material. Consequently, AVS in combination with the carbodiimide chemistry appears as a robust method for the immobilization of proteins and, for the first time, it is shown that it can be used to enhance the biological response to the material.
Demographic analysis of arrhenotokous parthenogenesis and bisexual reproduction of Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae)
Authors: Ding Tianbo , Chi Hsin , Gökçe Ayhan , Gao Yulin , Zhang Bin 
Published: February 2018

AbstractFrankliniella occidentalis(Pergande) (Thysanoptera: Thripidae) is a serious pest that is capable of bisexual and arrhenotokous reproduction. In arrhenotokous reproduction, virgin females initially produce male offspring; later, when their sons are sexually mature, the mothers begin bisexual reproduction by carrying out oedipal mating with their sons. Because a virgin female produces many male offspring before oedipal mating occurs, multiple oedipal mating is common. In this study, we investigated the effect of multiple oedipal mating on the population growth ofF. occidentalisby using the age-stage, two-sex life table theory. In the arrhenotokous cohorts, all unfertilized eggs developed into males. In the bisexual cohorts, the offspring sex ratio was significantly female biased with the mean number of female offspring and male offspring being 72.68 and 29.00, respectively. These were the same as the net reproductive rate of female offspring and male offspring. In arrhenotokous cohorts, the number of males available for oedipal mating significantly affected the production of female offspring. The number of female offspring increased as the number of sons available for oedipal mating increased. Correctly characterizing this unique type of reproduction will provide important information for predicting the timing of future outbreaks ofF. occidentalis, as well as aiding in formulating successful management strategies against the species.
Biomining of MoS2 with Peptide-based Smart Biomaterials
Authors: Cetinel Sibel , Shen Wei-Zheng , Aminpour Maral , Bhomkar Prasanna , Wang Feng , Borujeny Elham Rafie , Sharma Kumakshi , Nayebi Niloofar , Montemagno Carlo 
Published: February 2018

AbstractBiomining of valuable metals using a target specific approach promises increased purification yields and decreased cost. Target specificity can be implemented with proteins/peptides, the biological molecules, responsible from various structural and functional pathways in living organisms by virtue of their specific recognition abilities towards both organic and inorganic materials. Phage display libraries are used to identify peptide biomolecules capable of specifically recognizing and binding organic/inorganic materials of interest with high affinities. Using combinatorial approaches, these molecular recognition elements can be converted into smart hybrid biomaterials and harnessed for biotechnological applications. Herein, we used a commercially available phage-display library to identify peptides with specific binding affinity to molybdenite (MoS2) and used them to decorate magnetic NPs. These peptide-coupled NPs could capture MoS2under a variety of environmental conditions. The same batch of NPs could be re-used multiple times to harvest MoS2, clearly suggesting that this hybrid material was robust and recyclable. The advantages of this smart hybrid biomaterial with respect to its MoS2-binding specificity, robust performance under environmentally challenging conditions and its recyclability suggests its potential application in harvesting MoS2from tailing ponds and downstream mining processes.
Blood T1* correction increases accuracy of extracellular volume measurements using 3T cardiovascular magnetic resonance: Comparison of T1 and T1* maps
Authors: Shang Yongning , Zhang Xiaochun , Zhou Xiaoyue , Greiser Andreas , Zhou Zhengwei , Li Debiao , Wang Jian 
Published: February 2018

AbstractThe goals were to compare the differences between ECVL (extracellular volume derived from myocardial T1 and blood T1), ECVc (combination of myocardial T1 and blood T1*), and ECVnL (derived from myocardium T1* and blood T1*), and to explore the diagnostic accuracy of these factors for discriminating between controls and patients. The Modified Look-Locker Inversion Recovery sequence was performed in 42 subjects to generate both T1 and T1* maps. Native and post-contrast T1 values for myocardium and blood pool were obtained, and ECVL, ECVc, and ECVnL were then calculated. The global ECVc values were smaller than the ECVL values (0.006, 2.11%, p < 0.001) and larger than the ECVnL values (0.06, 21.6%, p < 0.001) in all participants. The ECVc led to a 4–6% increase in the AUC value and a 24–32% reduction in the sample size to differentiate between the controls and other patients when compared with the ECVL. Blood T1* correction can improve the precision of blood T1 values and can consequently increase the accuracy of the extracellular volume fraction measurement. The ECVc can be used to improve diagnostic accuracy and reduce the sample size required for a clinical study.
Spatial Release From Masking in Adults With Bilateral Cochlear Implants: Effects of Distracter Azimuth and Microphone Location
Authors: Davis Timothy J. , Gifford René H. 
Published: February 2018

PurposeThe primary purpose of this study was to derive spatial release from masking (SRM) performance-azimuth functions for bilateral cochlear implant (CI) users to provide a thorough description of SRM as a function of target/distracter spatial configuration. The secondary purpose of this study was to investigate the effect of the microphone location for SRM in a within-subject study design.MethodSpeech recognition was measured in 12 adults with bilateral CIs for 11 spatial separations ranging from −90° to +90° in 20° steps using an adaptive block design. Five of the 12 participants were tested with both the behind-the-ear microphones and a T-mic configuration to further investigate the effect of mic location on SRM.ResultsSRM can be significantly affected by the hemifield origin of the distracter stimulus—particularly for listeners with interaural asymmetry in speech understanding. The greatest SRM was observed with a distracter positioned 50° away from the target. There was no effect of mic location on SRM for the current experimental design.ConclusionOur results demonstrate that the traditional assessment of SRM with a distracter positioned at 90° azimuth may underestimate maximum performance for individuals with bilateral CIs.
Energy aware simplicial processor for embedded morphological visual processing in intelligent internet of things
Authors: Villemur M. , Julian P. , Andreou A. G. 
Published: February 2018

This Letter presents the architecture implementation and testing of an single instruction multiple data (SIMD) processor for energy aware embedded morphological visual processing using the simplicial piece‐wise linear approximation. The architecture comprises a linear array of 48 × 48 processing elements, each connected to an eight‐neighbour clique operating on binary input and state data. The architecture is synthesised from a custom designed ultra low‐voltage CMOS library and fabricated in a 55 nm CMOS technology. The chip is capable of dynamic voltage/frequency scaling with power supplies between 0.5 and 1.2 V. The fabricated chip achieves an overall performance of 293 TOPS/W with dynamic energy dissipation efficiency of 3.4 fJ per output operation at 0.6 V.
Microsurgical Resection of Suprasellar Craniopharyngioma—Technical Purview
Authors: Nanda Anil , Narayan Vinayak , Mohammed Nasser , Savardekar Amey , Patra Devi 
Published: February 2018

Objectives Complete surgical resection is an important prognostic factor for recurrence and is the best management for craniopharyngioma. This operative video demonstrates the technical nuances in achieving complete resection of a suprasellar craniopharyngioma.
Design and Setting The surgery was performed in a middle-aged lady who presented with the history of progressive bitemporal hemianopia and excessive sleepiness over 8 months. On imaging, suprasellar craniopharyngioma was identified. The tumor was approached through opticocarotid cistern and lamina terminalis. Exposure of bilateral optic nerves, right internal carotid artery, anterior cerebral artery, and its perforator branches was then afforded and the tumor was gross totally resected.
Results The author demonstrates step-by-step technique of microsurgical resection of suprasellar craniopharyngioma. The narrow corridor to deeper structures, intricacies of multiple perforator vessels, and the technique of arachnoid and capsule dissection are the main challenging factors for the gross total resection of craniopharyngioma. The tumor portion which lies under the ipsilateral optic nerve is a blind spot region with a high chance of leaving residual tumor. Mobilization of optic nerve may endanger visual function too. The use of handheld mirror [‘mirror-technique’] helps in better visualization of this blind spot and achieve complete excision.
Conclusions The technical pearls of craniopharyngioma surgery include the optimum utilization of translamina terminalis route, wide opening of the cisterns, meticulous separation of deep perforator vessels, capsular mobilization/traction avoidance, and the use of “mirror-technique” for blind-spot visualization. These surgical strategies help to achieve complete resection without causing neurological deficit.The link to the video can be found at: https://youtu.be/9wHJ4AUpG50.
Endoscopic Endonasal Transoculomotor Triangle Approach for the Resection of a Pituitary Adenoma with Ambient Cistern Extension
Authors: Zenonos Georgios , Wang Eric , Fernandez-Miranda Juan 
Published: February 2018

Objectives The current video presents the nuances of the endoscopic endonasal transoculomotor triangle approach for the resection of a pituitary adenoma with extension into the ambient cistern.
Design The video analyzes the presentation, preoperative workup and imaging, surgical steps and technical nuances of the surgery, the clinical outcome, and follow-up imaging.
Setting The patient was treated by a skull base team consisting of a neurosurgeon and an ENT surgeon at a teaching academic institution.
Participants The case refers to a 62-year-old female who presented with vision loss and headaches, and was found to have a pituitary adenoma with extension into the ambient cistern.
Main Outcome Measures The main outcome measures consist of the reversal of the patient symptoms (headaches), the recurrence-free survival based on imaging, as well as the absence of any complications.
Results The patient's headaches improved. There was no evidence of recurrence.
Conclusions The endoscopic endonasal transoculomotor triangle approach is safe and effective for addressing pituitary tumors which extend into the ambient cistern.The link to the video can be found at: https://youtu.be/EBLwEWhohxY.
Extended Endoscopic Endonasal Resection of a Suprasellar and Third Ventricular Retrochiasmatic Craniopharyngioma with a Narrow Pituitary Gland–Optic Chiasm Interval: Techniques to Optimize Resection
Authors: Kenning Tyler , Pinheiro-Neto Carlos 
Published: February 2018

AbstractThe extended endoscopic endonasal approach can be utilized to surgically treat pathology within the suprasellar space. This relies on a sufficient corridor and interval between the superior aspect of the pituitary gland and the optic chiasm. Tumors located in the retrochiasmatic space and within the third ventricle, however, may not have a widened interval through which to work. With mass effect on the superior and posterior aspect of the optic chiasm, the corridor between the chiasm and the pituitary gland might even be further narrowed. This may negate the possibility of utilizing the endoscopic endonasal approach for the management of pathology in this location. We present a case of a retrochiasmatic craniopharyngioma with a narrow resection corridor that was treated with the extended endoscopic approach and we review techniques to potentially overcome this limitation.The link to the video can be found at: https://youtu.be/ogRZj-aBqeQ.
The Impact of Computed Tomography on Decision Making in Tibial Plateau Fractures
Authors: Castiglia Marcello , Nogueira-Barbosa Marcello , Messias Andre , Salim Rodrigo , Fogagnolo Fabricio , Schatzker Joseph , Kfuri Mauricio 
Published: February 2018

AbstractSchatzker introduced one of the most used classification systems for tibial plateau fractures, based on plain radiographs. Computed tomography brought to attention the importance of coronal plane-oriented fractures. The goal of our study was to determine if the addition of computed tomography would affect the decision making of surgeons who usually use the Schatzker classification to assess tibial plateau fractures. Image studies of 70 patients who sustained tibial plateau fractures were uploaded to a dedicated homepage. Every patient was linked to a folder which contained two radiographic projections (anteroposterior and lateral), three interactive videos of computed tomography (axial, sagittal, and coronal), and eight pictures depicting tridimensional reconstructions of the tibial plateau. Ten attending orthopaedic surgeons, who were blinded to the cases, were granted access to the homepage and assessed each set of images in two different rounds, separated to each other by an interval of 2 weeks. Each case was evaluated in three steps, where surgeons had access, respectively to radiographs, two-dimensional videos of computed tomography, and three-dimensional reconstruction images. After every step, surgeons were asked to present how would they classify the case using the Schatzker system and which surgical approaches would be appropriate. We evaluated the inter- and intraobserver reliability of the Schatzker classification using the Kappa concordance coefficient, as well as the impact of computed tomography in the decision making regarding the surgical approach for each case, by using the chi-square test and likelihood ratio. The interobserver concordance kappa coefficients after each assessment step were, respectively, 0.58, 0.62, and 0.64. For the intraobserver analysis, the coefficients were, respectively, 0.76, 0.75, and 0.78. Computed tomography changed the surgical approach selection for the types II, V, and VI of Schatzker (p < 0.01). The addition of computed tomography scans to plain radiographs improved the interobserver reliability of Schatzker classification. Computed tomography had a statistically significant impact in the selection of surgical approaches for the lateral tibial plateau.
TFCC Injuries: Meta-Analysis and Comparison of Diagnostic Imaging Modalities
Authors: Treiser Matthew , Crawford Kayva , Iorio Matthew 
Published: February 2018

Background Imaging of the triangular fibrocartilaginous complex (TFCC) remains difficult, as no single imaging modality demonstrates perfect sensitivity and specificity.
Purpose This study performs a meta-analysis of multiple previous publications to guide noninvasive imaging selection for the diagnosis of TFCC injuries.
Methods A literature search was performed and conducted. Studies were included that compared the diagnostic accuracy of magnetic resonance imaging (MRI), magnetic resonance arthrography (MRA), and computed tomography (CT)/computed tomographic arthrography (CTA) for the evaluation of TFCC injuries. All studies included either arthroscopic or open surgical findings as the “gold standard.” A meta-analysis was performed comparing the diagnostic accuracy of MRA, MRI, and CT for the detection of TFCC injuries.
Results Initial search returned 2,568 candidate articles. Studies were then reviewed and narrowed yielding a total of 28 independent studies (20 MRI, 9 MRA, 4 CT/CTA with some studies including multiple modalities) considered in the qualitative data synthesis. Pooling of the raw data in a meta-analysis demonstrated sensitivities of 0.76 (0.72–0.80), 0.78(0.70–0.84), and 0.89 (0.81–0.95) for MRI, MRA, and CT arthrogram, respectively, with specificities of 0.82 (0.77–0.86), 0.85 (0.77–0.92), and 0.89 (0.81–0.95), respectively. Additionally, across all imaging modalities, diagnostic accuracy was highest for central TFCC lesions versus peripheral lesions.
Conclusion This study represents the largest meta-analysis to date to compare multiple imaging modalities for the diagnosis of TFCC injuries. Pooled data demonstrated that CTA and MRA had statistically equivalent sensitivity and specificity for the diagnosis of TFCC injuries. Diagnostic accuracy was highest for central TFCC injuries.