bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis
Authors: Adams Taylor S. , Schupp Jonas C. , Poli Sergio , Ayaub Ehab A. , Neumark Nir , Ahangari Farida , Chu Sarah G. , Raby Benjamin A. , DeIuliis Giuseppe , Januszyk Michael , Duan Qiaonan , Arnett Heather A. , Siddiqui Asim , Washko George R. , Homer Robert , Yan Xiting , Rosas Ivan O. , Kaminski Naftali 
Published: September 2019

AbstractWe provide a single cell atlas of Idiopathic Pulmonary Fibrosis (IPF), a fatal interstitial lung disease, focusing on resident lung cell populations. By profiling 312,928 cells from 32 IPF, 29 healthy control and 18 chronic obstructive pulmonary disease (COPD) lungs, we demonstrate that IPF is characterized by changes in discrete subpopulations of cells in the three major parenchymal compartments: the epithelium, endothelium and stroma. Among epithelial cells, we identify a novel population of IPF enriched aberrant basaloid cells that co-express basal epithelial markers, mesenchymal markers, senescence markers, developmental transcription factors and are located at the edge of myofibroblast foci in the IPF lung. Among vascular endothelial cells in the in IPF lung parenchyma we identify an expanded cell population transcriptomically identical to vascular endothelial cells normally restricted to the bronchial circulation. We confirm the presence of both populations by immunohistochemistry and independent datasets. Among stromal cells we identify fibroblasts and myofibroblasts in both control and IPF lungs and leverage manifold-based algorithms diffusion maps and diffusion pseudotime to infer the origins of the activated IPF myofibroblast. Our work provides a comprehensive catalogue of the aberrant cellular transcriptional programs in IPF, demonstrates a new framework for analyzing complex disease with scRNAseq, and provides the largest lung disease single-cell atlas to date.
MeasuringC. elegansspatial foraging and food intake using bioluminescent bacteria
Authors: Ding Siyu Serena , Sarkisyan Karen S. , Brown Andre E. X. 
Published: September 2019

ABSTRACTFor most animals, feeding includes two behaviours: foraging to find a food patch and food intake once a patch is found. The nematodeCaenorhabditis elegansis a useful model for studying the genetics of both behaviours. However, most methods of measuring feeding in worms quantify either foraging behaviour or food intake but not both. Imaging the depletion of fluorescently labelled bacteria provides information on both the distribution and amount of consumption, but even after patch exhaustion a prominent background signal remains, which complicates quantification. Here, we used a bioluminescentEscherichia colistrain to quantifyC. elegansfeeding. With light emission tightly coupled to active metabolism, only living bacteria are capable of bioluminescence so the signal is lost upon ingestion. We quantified the loss of bioluminescence using N2 reference worms andeat-2mutants, and found a nearly 100-fold increase in signal-to-background ratio and lower background compared to loss of fluorescence. We also quantified feeding using aggregatingnpr-1mutant worms. We found that groups ofnpr-1mutants first clear bacteria from each other before foraging collectively for more food; similarly, during high density swarming, only worms at the migrating front are in contact with bacteria. These results demonstrate the usefulness of bioluminescent bacteria for quantifying feeding and suggest a hygiene hypothesis for the function ofC. elegansaggregation and swarming.
An anti-interference detection algorithm for parking monitoring systems
Authors: Dong Ani , Zhang Zusheng , Chen Jiaming 
Published: September 2019

Purpose
Magnetic sensors have recently been proposed for parking occupancy detection. However, there has adjacent interference problem, i.e. the magnetic signal is easy to be interfered by the vehicles which are parking on adjacent spaces. The purpose of this paper is to propose a sensing algorithm to eliminate the adjacent interference.

Design/methodology/approach
The magnetic signals are converted to the pattern representation sequences, and the similarity is calculated using the pattern distance. The detection algorithm includes two levels: local decision and data fusion. In the local decision level, the sampled signals can be divided into three classes: vacant, occupied and uncertain. Then a collaborative decision is used to fusion the signals which belong to the uncertain class for the second level.

Findings
An experiment system included 60 sensor nodes that were deployed on bay parking spaces. Experiment results show that the proposed algorithm has better detection accuracy than existing algorithms.

Originality/value
This paper proposes a data fusion algorithm to eliminate adjacent interference. To balance the energy consumption and detection accuracy, the algorithm includes two levels: local decision and data fusion. In most of cases, the local decision can obtain the accurate detection result. Only the signals that cannot be correctly detected at the local level need data fusion operation.
The well-being of the early career teacher: a review of the literature on the pivotal role of mentoring
Authors: Squires Vicki 
Published: September 2019

PurposeThe purpose of this paper is to explore the extant literature with regard to the role of mentorship in promoting the well-being of early career teachers.Design/methodology/approachThis paper was comprised of a review of the current literature. Key terms were used to identify initial sources. The search was narrowed further by using the Boolean operator AND to link key terms.FindingsMuch of the literature exploring mentorship and induction focuses on the formal structures and the targeted learning outcomes of the processes. However, the emotional and personal support afforded new teachers through the development of relationships with mentors is being recognized as contributing high value to the continued retention efforts. Although there are promising practices with regard to induction programs and formal mentorship arrangements in some schools, these practices are very scattered and may not even be equally well established within one school district.Research limitations/implicationsImplementation of models that are focused on personal and professional support of new teachers could provide an avenue of research examining teachers’ perceptions of well-being and resiliency. Longitudinal, pan-provincial and pan-national research is necessary for developing more support for systemic implementation of mentorship models.Originality/valueWhile there is research identifying existing programs and induction models, this paper uses the lens of early career teacher well-being to point out promising practices and additional considerations for adopting a holistic approach to mentorship. This mentorship model may result in better personal and professional outcomes for new teachers.
Achieving automotive suppliers’ mass customization through modularity
Authors: Wu Qun , Liao Kun , Deng Xiaodong , Marsillac Erika 
Published: September 2019

PurposePrevious literature tends to combine postponement and modularity or view them as parallel factors to achieve mass customization (MC) while ignoring the sequence of a firm to design and implement operations and supply chain strategy. Based on a customer-oriented strategy and theories of organizational information processing theory, three-dimensional (3D) concurrent engineering and resource dependency, the purpose of this paper is to propose a sequential model reflecting the sequence of practices as well as an overview picture for a firm to achieve MC.Design/methodology/approachThe model links three company antecedents – postponement orientation, operational alignment and information sharing, to three company supply chain practices – product and process modularity and supplier segmentation. These practices, in turn, lead to the company’s MC capabilities. The proposed model is tested with a data set collected from automotive suppliers in China and in the USA. Structural equation modeling is used to analyze the data and test the model.FindingsThe results suggest that, for suppliers to achieve MC, postponement orientation and operational alignment are vital antecedents. The results also reveal the important responsibility and role of information sharing practices in coordinating suppliers’ modularity practices.Originality/valueThis research provides three findings that are of value to both academicians and practitioners of supply chain management. First, this study originally proposed and empirically tested that a postponement orientation is an antecedent of product and process modularity and supplier segmentation to achieve MC in the automotive sector, contrary to the traditional view of parallel relationships for both. Second, it developed and verified measures of operational alignment and supplier segmentation for future research use. Third, the vital role of information sharing to coordinate internal and external supply chain practices to achieve MC is empirically supported.
In depth study of lead frame tape residuein quad flat non-leaded package
Authors: Nadaraja Shri Kumaran , Yap Boon Kar 
Published: September 2019

Purpose
Lead frame tape is a crucial support for lead frames in the IC assembly process. The tape residue on the quad flat non-leaded (QFN) could result in low reliability and failure in electrical conductivity tests. The tape residue would affect overall performance of the chips and contribute to low pass yield. The purpose of this paper is to present an in-depth study of tape residue and factors that may affect it.

Design/methodology/approach
An experiment using lead frame and tapes from three manufacturers with two types of die bond adhesives, namely, die attach film (DAF) and wafer back coating (WBC), was conducted. Copper (Cu) wire bonding and die bonding performances were measured in terms of process capability, stitch bond strength and die attach strength.

Findings
Results showed that no tape residue was observed on the thermoplastic adhesive-based lead frames manufactured by Hitachi after the de-taping process because of the tape’s thermoplastic adhesive properties.

Originality/value
This paper studies the occurrence of tape residue and a viable solution for it through the correct process optimization and combination of semiconductor manufacturing materials. Factors that may affect tape residue have also been studied and further research can be done to explore other options in the future as an alternate solution.
Factors affecting political participation (Jordanian universities students' voting: field study 2017-2018)
Authors: Alelaimat Mohammad Soud 
Published: September 2019

PurposeThis study aims to identify the factors affecting the political participation of Jordanian university students, especially their voting in national and local elections. The study examines the impact of gender, age, family income and regional affiliation that represent important social and economic factors affecting political participation on the voting of Jordanian university students.Design/methodology/approachQuantitative research method was used in this study. The study population contained three Jordanian universities representing the various segments of the Jordanian society: Al-Al Bayt University (Northern Region), Jordanian University (Central Region) and Mu'tah University (Southern Region). The study relied on a purposive sample of 900 students, 300 students per university (150 males and 150 females). The survey was conducted in the academic year 2018-2019. A questionnaire reviewed by two jurors (peer reviewers) was used to collect the data.FindingsThe study concluded that the gender, age, family income and regional affiliation factors affect the voting of Jordanian university students in national and local elections. The more the gender varies, the more the voting shifts in favor of males students. The more the age varies, the more the voting shifts in favor of older students. The more the family income varies, the more the voting shifts in favor of high-income students. The more the regional affiliation varies, the more the voting shifts in favor of Jordanians students.Originality/valueThis study is an approach to interpret the factors affecting voting of Jordanian university students, such as gender, age, family income and regional affiliation, which led to different voting in the national and local elections.
Low RH and temperature effect on 0201 sized passive components during SMT mounting
Authors: Asghar Rafiq , Rehman Faisal , Aman Ali , Iqbal Kashif 
Published: September 2019

Purpose
Low relative humidity (RH) effect surface mount devices in numerous ways. The smaller size (0201) capacitor and resistor start wasting when RH is low. Due to low RH, electrostatic charges built-up on the surface of surface mount devices (SMDs) and component’s reel. The positive charged SMDs stick with the negatively charged reel tape and are wasted. This paper comprehensively explores the environmental effects on 0201 size surface mount devices during mounting process. Different type and size of surface mount devices are tested in low and desired RH to validate the effectiveness of the proposed approach. This paper will also highlight high electrostatic discharge (ESD) due to low RH which can be detrimental for small size surface mount devices. The experimental and graphical illustrations will stipulate the results of success rate for mounting components. The effect on ESD, subsequently varying temperature and humidity will also be analyzed.

Design/methodology/approach
In this paper, 0201 SDMs will be considered for analysis. The surface mount technology (SMT) plant temperature and humidity has been varied to examine the properties of small size SMDs. Total 5 hours production data are collected from Laptop motherboard production environment. This approach is applicable to all SMT environment.

Findings
The authors reduced the wastage of 0201 chip size resistor and capacitor. Total 11 components are selected of this size, and there success rate is observed during mounting. These components are first observed in harsh environment where the temperature is first set to 20ºC and RH is set to 25 per cent. The success rate of these components is very low due to component’s wastage. When the plant temperature is set to 25ºC and RH is set to 45 per cent, the success rate of mounting increased up to 100 per cent. A single component placement success rate with respect to RH is observed for one month. The results are shown in Table IV. It can be seen that the success rate is near 100 per cent when RH and temperature is maintained in production environment. To eliminate the ESD build-up in material and equipment in manufacturing environment humidification is a very effective way. When the RH is kept to 45 per cent, the moisture content of the air is a natural conductor and earths any ESD in environment.

Originality/value
Experimental data have been obtained from Laptop motherboard manufacturing process to validate the effectiveness of proposed approach.
Risk of cutaneous herpes zoster in patients with spondyloarthritis treated with conventional and biologic disease‐modifying antirheumatic drugs
Authors: Wong Sabrina Ching Tung , Li Iris Wai Sum , Ng Alexandra Hoi Yan , Lau Chak Sing , Chung Ho Yin 
Published: September 2019

AbstractObjectivesTo investigate the risk of cutaneous herpes zoster (HZ) in spondyloarthritis (SpA) compared with that in rheumatoid arthritis (RA), and in disease‐modifying antirheumatic drugs (DMARDs) used in SpA.MethodA total of 727 patients with an expert diagnosis of SpA were identified retrospectively from four rheumatology centers in Hong Kong. Electronic medical records from 1995 to 2018 were reviewed for incidence of cutaneous HZ and demographic data including age, sex, comorbidities, smoking and drinking status. DMARDs used included sulphasalazine, methotrexate, leflunomide, steroids, etanercept, infliximab, adalimumab, golimumab, secukinumab and ustekinumab. Cox regression models were used to evaluate hazard ratios (HRs) of different DMARDs in patients with SpA. Propensity score was used for matching and comparison with 857 patients with RA.ResultsThere were 23 cases of cutaneous HZ in patients with SpA and 59 cases in patients with RA. Among patients with SpA, 7 cases of cutaneous HZ may be attributed to sulfasalazine treatment, 7 to methotrexate, 2 to leflunomide, 2 to infliximab, 1 to etanercept, 2 to adalimumab, and 1 to secukinumab. Risks of cutaneous HZ were the same in SpA (stratified HR 0.97; 95% CI 0.58; 1.61; P = .89) and RA. Methotrexate (adjusted HR 3.47; 95% CI 1.25; 9.63; P = .02) and infliximab (adjusted HR 10.67; 95% CI 1.37; 82.88; P = .02) were found to be associated with HZ after adjustments for traditional risk factors.ConclusionRisk of cutaneous HZ in SpA was not lower than in RA. Methotrexate and infliximab were associated with cutaneous HZ in SpA.
Habitat use, seasonality and demography of the broadnose sevengill shark Notorynchus cepedianus in central Patagonia: Another piece of the puzzle
Authors: Irigoyen Alejo J. , Bovcon Nelson , Trobbiani Gastón , De Wysiecki Agustín M. , Argemi Federico , Jaureguizar Andrés J. 
Published: September 2019

AbstractThe habitat use, seasonality and demography of the broadnose sevengill shark Notorynchus cepedianus were investigated in central Patagonia, where a data gap exists for the species. Catch and effort and video‐derived indices indicated high relative abundance of sharks during warm months. Video stations revealed differences in the spatial use by sharks, being more frequently observed in the inner section of the bay. Complementary tagging efforts evidenced both a seasonal residence pattern and site fidelity between consecutive warm seasons. Juveniles outnumbered adults, which suggests that they may use the study area as a secondary nursing ground. Evidence from spontaneous regurgitation further suggests that prey abundance may be driving the seasonal occurrence of sharks in the region. This study allows for a more comprehensive understanding of the population structure and dynamics of sevengill sharks in the Southwest Atlantic.Abstract in Spanish is available with online material.
Microbial responses to warming enhance soil carbon loss following translocation across a tropical forest elevation gradient
Authors: Nottingham Andrew T. , Whitaker Jeanette , Ostle Nick J. , Bardgett Richard D. , McNamara Niall P. , Fierer Noah , Salinas Norma , Ccahuana Adan J. Q. , Turner Benjamin L. , Meir Patrick 
Published: September 2019

AbstractTropical soils contain huge carbon stocks, which climate warming is projected to reduce by stimulating organic matter decomposition, creating a positive feedback that will promote further warming. Models predict that the loss of carbon from warming soils will be mediated by microbial physiology, but no empirical data are available on the response of soil carbon and microbial physiology to warming in tropical forests, which dominate the terrestrial carbon cycle. Here we show that warming caused a considerable loss of soil carbon that was enhanced by associated changes in microbial physiology. By translocating soils across a 3000 m elevation gradient in tropical forest, equivalent to a temperature change of ± 15 °C, we found that soil carbon declined over 5 years by 4% in response to each 1 °C increase in temperature. The total loss of carbon was related to its original quantity and lability, and was enhanced by changes in microbial physiology including increased microbial carbon‐use‐efficiency, shifts in community composition towards microbial taxa associated with warmer temperatures, and increased activity of hydrolytic enzymes. These findings suggest that microbial feedbacks will cause considerable loss of carbon from tropical forest soils in response to predicted climatic warming this century.
Flexibly Using the Surveys of Enacted Curriculum to Study Alignment
Authors: Polikoff Morgan S. , Gasparian Hovanes , Korn Shira , Gamboa Martin , Porter Andrew C. , Smith Toni , Garet Michael S. 
Published: September 2019

AbstractAs the standards movement continues into its third decade, there remains a need for alignment methodologies that can be broadly applied to study instruction and policy. This article reports on a series of development efforts meant to revise the Surveys of Enacted Curriculum (SEC) surveys and methods to study the implementation of new college‐ and career‐readiness standards. The work included a meeting of content experts, a series of cognitive interviews, two validation studies, and a small pilot. We discuss both the results of the specific studies and the implications of the work for other potential users of the SEC or SEC‐like tools.
Biogeographic conundrum: Why so few stream nerite species (Gastropoda: Neritidae) in Australia?
Authors: Davis Andrew R. , Ponder Winston 
Published: September 2019

Abstract

Nerites (Gastropoda: Neritidae) are prominent members of tropical marine and freshwater gastropod faunas and rich assemblages can be found in many streams of islands in the Indo‐Pacific. For example, the streams of Fiji and New Guinea each support at least 23 species of freshwater neritimorphs, with representatives in the genera: Clithon, Neripteron, Neritilia, Neritina, Neritona, Neritodryas, Septaria, and Vittina.

The striking diversity of this group in the small coastal streams of Pacific Islands contrast with a paucity of taxa in tropical Australia, despite northern Australia occupying a similar latitude. Just four taxa have been reported from Australia and only two can be considered common. These patterns are in marked contrast to the wide distribution of many marine nerites in the Pacific and conflicts with Island Biogeography Theory.

Strikingly, many of these stream taxa have adopted an amphidromous lifestyle; adult gastropods feed and reproduce in freshwater, whereas larvae are swept to the ocean and undergo a marine dispersive phase before settling near the entrance to creeks and re‐entering these freshwater systems as crawling juveniles.

Rapid transit of larvae to the ocean via short, steep, fast‐flowing streams may offer an explanation for this biogeographic conundrum. Larvae that do not reach the ocean within a few days may starve or exhibit poor survival. Hence, the disruption of stream–ocean connectivity may explain the low diversity of these taxa in northern Australia. Sea level rise in northern Australia in the current interglacial has further weakened stream–ocean connectivity with the development of vast flood plains and slow‐moving rivers.

We contend that: (1) poor stream–ocean connectivity is not conducive to the maintenance of populations of nerites in northern Australia; and (2) new records of freshwater nerites may be revealed by surveys in short, steep coastal streams of northern Australia.