bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liver Multiacinar Regenerative Nodules: Imaging Findings and Clinical Implications
Authors: Donato Henrique , Andrade Luísa , Bastati Nina , Cipriano Augusta , Ba-Ssalamah Ahmed , Caseiro-Alves Filipe 
Published: March 2019

Introduction: Multiacinar regenerative nodules are benign hepatocellular nodules related to vascular disturbances of the liver. They strongly resemble conventional focal nodular hyperplasia but are connected to different clinical settings, typically chronic liver disease. The purpose of the present study was to describe the key imaging features of these lesions and compare them with a control arm of focal nodular hyperplasia.Material and Methods: A blinded consensus review of liver magnetic resonance consisting of 26 cases of multiacinar regenerative nodules and 25 cases of focal nodular hyperplasia was performed. Lesion size, shape, margins, structure, T1 and T2 signal intensity, diffusion and contrast-enhanced features (including hepatobiliary phase), presence of a central scar and of a peripheral hypointense rim were compared between the two groups.Results: Significant differences between multiacinar regenerative nodules and focal nodular hyperplasia included size (median 2.35 cm, IQR: 2.13, vs 6.00 cm, IQR: 5.20, respectively, p < 0.001), presence of a peripheral hypointense rim after contrast (n = 9 vs n = 2 cases, p = 0.038) and of a central scar (n = 9 vs n = 20, p = 0.002). There were no other significant differences.Discussion: Overall multiacinar regenerative nodules and focal nodular hyperplasia have very similar imaging features but lack of a central scar and presence of a hypointense rim should suggest a diagnosis of multiacinar regenerative nodules.Conclusions: Recognition of the imaging findings of multiacinar regenerative nodules can explain some atypical cases of focal nodular hyperplasia, avoiding unnecessary biopsies. They may also be the trigger to investigate an unsuspected underlying liver vascular abnormality.
Iron Deficiency and Obesity – Are we Diagnosing with Appropriate Indicators?
Authors: Monteiro Ana Margarida , Fernandes Vera , Matta-Coelho Cláudia , Paredes Sílvia , Lopes Pereira Maria , Marques Olinda , Alves Marta 
Published: March 2019

Introduction: We aim to define the iron deficiency prevalence and eventual differences between obese patients with and without metabolic syndrome.Material and Methods: Analysis of patients evaluated at multidisciplinary consultation of obesity in our institution between 2013 and 2015 (n = 260). Iron deficiency: ferritin levels < 15 ng/mL. Exclusion criteria: prior bariatric surgery; lack of ferritin or hemoglobin determinations.Results: We analyzed data from 215 patients (84.2% female) with a mean age of 42.0 ± 10.3 years. The median body mass index was 42.5 (40.0 - 46.8) kg/m2 and 52.1% had metabolic syndrome. Iron deficiency was present in 7.0%, with no differences between genders or between patients with or without metabolic syndrome. Hypertension was associated with lower prevalence of iron deficiency. Type 2 diabetes and hypertension patients had higher levels of ferritin. The multivariate analysis showed that metabolic syndrome and increasing body mass index were predictive of higher risk of iron deficiency while hypertension predicted lower odds of iron deficiency.Discussion: The prevalence of iron deficiency was similar in other published studies. Iron deficiency may be underdiagnosed if based only on ferritin concentrations. In our study, diabetes and hypertension appear to contribute to the increase in ferritin levels described in obesity.Conclusion: Ferritin may not be a reliable index for evaluating iron stores in obese patients, particularly when associated with comorbidities such as type 2 diabetes and hypertension. Further studies are needed to guide the diagnosis and iron supplementation in these patients.
Tromboembolismo Venoso em Idade Pediátrica: Estudo Retrospetivo de 15 Anos
Authors: Andrade Joana Verdelho , Magalhães Joana , Resende Catarina , Gomes Dora , Laranjo Gabriela , Campos Joana , Santos Elisabete , Faria Cristina 
Published: March 2019

Introdução: O tromboembolismo pulmonar e trombose venosa profunda ocorrem em idade pediátrica com incidência, morbilidade e mortalidade desconhecidas. O objetivo foi rever epidemiologia, apresentação clínica, exames complementares de diagnóstico e prognóstico de doentes com tromboembolismo pulmonar e trombose venosa profunda.Material e Métodos: Estudo retrospetivo, descritivo e analítico de doentes pediátricos internados num hospital de nível II por tromboembolismo pulmonar e trombose venosa profunda, entre 2000 e 2014. Estudaram-se características demográficas, história clínica, comorbilidades e fatores de risco.Resultados: Foram internados 11 doentes (sete com tromboembolismo pulmonar, cinco com trombose venosa profunda e um com ambos), 64% do género feminino e idade média de 16 anos. Todos os doentes com tromboembolismo pulmonar referiam toracalgia/dispneia, 25% síncope/palpitações e 25% febre. Todos os doentes com trombose venosa profunda referiam dor no local da obstrução, 83% edema/cianose do membro afetado e 17% febre. O estudo da trombofilia positivo foi o fator de risco mais frequente nas duas entidades. O valor médio dos D-dímeros foi 3252 ug/L e 2660 ug/L no tromboembolismo pulmonar e trombose venosa profunda, respetivamente. Todos os doentes iniciaram anticoagulação, três necessitaram de cuidados intensivos, três apresentaram sequelas e houve um óbito.Discussão: Todos os doentes tinham pelo menos um fator de risco associado e as condições de hipercoagulabilidade herdadas foram o fator de risco mais frequentemente encontrado nos nossos adolescentes.Conclusão: O aumento da incidência na população pediátrica descrito na literatura pode ser atribuído à crescente sensibilização para esta patologia, aos avanços médicos e aumento da sobrevida de doenças crónicas. Escasseiam recomendações baseadas na evidência que identifiquem os doentes com risco de trombose, para que as decisões possam ser tomadas de forma cuidadosa, equilibrando o risco e benefício em cada caso.
Validation of the Skindex-29 Questionnaire: Portuguese Version (Portugal)
Authors: Carvalho Daniela , Aguiar Pedro , Palma-Carlos Antero 
Published: March 2019

Introduction: There is an increasing interest regarding the impact of skin diseases on quality of life. Skindex-29 is a questionnaire developed to evaluate this impact. This study aimed to validate Skindex-29 for the Portuguese population.Material and Methods: From the 81 approached patients from two clinics, only 75 finished the study: 35 with skin disease and 40 without. A translation and back-translation were performed. Concerning accuracy and discrimination power, the scores were submitted to ROC curve analysis after being compared between both groups through Mann-Whitney test. Internal consistency was measured using Cronbach’s α coefficient. Test/retest of each scale was assessed by the intra-class correlation coefficient, and by Kappa coefficient of agreement. Convergent validity was evaluated through Spearman correlations between Skindex-29 scores and SF-12 subscales. SPSS statistics and values of p < 0.05 with 95% confidence intervals were considered statistically significant.Results: The Skindex-29 demonstrated to be an accurate instrument and statistically significant differences were found when comparing the disease and without-disease groups (p < 0.001). The reliability was high (Cronbach’s α > 0.80) for each dimension ('Symptoms', 'Emotions' and 'Functioning') and for test-retest (ICC > 0.90, K > 0.494). About convergent validity, Skindex-29 Total score and the questions about 'Symptoms' and 'Functioning' were statistically correlated with the questions regarding the physical state of the SF-12 (-0.478; -0.459; -0.405, respectively).Discussion: Results suggest that Skindex-29 can be used as an instrument to evaluate skin diseases’ effect on quality of life in Portugal, being accurate and reliable. Despite having similar general health profiles as other individuals, dermatological patients showed a lower quality of life due to their disease. Results showed that Skindex-29 was better at assessing physical components rather than mental oremotional components.Conclusion: Skindex-29 appears to have evidence of validity including accuracy and reliability to be used as an instrument to evaluate the impact of skin diseases on quality of life in Portugal.
Neuroborreliose Tardia num Estudante em Programa Erasmus
Authors: Santos Fábio Videira , Cipriano Ana , Abreu Miguel Araújo , Andrade Carlos , Sarmento-Castro Rui 
Published: March 2019

A doença de Lyme é uma zoonose endémica nos Estados Unidos da América (EUA), na Ásia e no continente europeu, nomeadamente nos países do centro da Europa. Trata-se de uma doença multissistémica, com manifestações cutâneas, articulares, neurológicas e cardíacas, que variam de acordo com a fase da doença. Apresentamos o caso de uma neuroborreliose tardia num jovem estudante belga a residir temporariamente no Porto. Discutimos a importância da suspeita epidemiológica, a investigação etiológica, os critérios de diagnóstico e o tratamento mais adequado.
Anxiety, Depression and Academic Performance: A Study Amongst Portuguese Medical Students Versus Non-Medical Students
Authors: Moreira de Sousa João , Moreira Cátia A. , Telles-Correia Diogo 
Published: March 2019

Introduction: The aim of the study is to assess the prevalence of anxiety and depressive symptoms in Portuguese medical students compared to students of other faculties, and the possible impact those symptoms have on academic performance.Material and Methods: A cross-sectional study was conducted in a sample of 750 students: 512 medical students and 238 nonmedical students. All students anonymously completed a socio-demographic survey and the Hospital Anxiety and Depression Scale (HADS). Statistical analysis was performed using the chi-square test, Mann-Whitney test, Spearman correlation coefficient or Kruskal-Wallis test.Results: We found a prevalence of 21.5% (n = 161) for anxiety symptoms and 3.7% (n = 28) for depressive symptoms. Being a medical student was more significantly associated with symptoms of anxiety (p = 0.034) compared with other students. Depressive symptoms were slightly associated with poor academic performance (p < 0.01). A percentage of 59.6% (n = 96) of students with anxiety symptoms and 46.4% (n = 13) of students with depressive symptoms did not seek medical or psychological care at that time.Discussion: Medical students in this sample seem to have more symptoms of anxiety, possibly explained by a higher number of female students in that sample. Depressive symptoms could be associated with poor academic performance in both groups, but an evident correlation was not established.Conclusion: Considering the high levels of anxiety symptoms, the possible impact of depressive symptoms in academic performance and the lack of psychiatric or psychological follow-up reported in this study, it is urgent to develop adequate means of support to improve students’ well-being and mental health.
Synthesis of noval gold nanomaterials and it's detection of sewage
Authors: Nie Furong , Ai Jun 
Published: March 2019

Abstract
In this article we report a novel approach to polyvinyl pyrrolidone k-30 (PVP)-templated formation of fluorescent gold nanoparticles (Au NPs) with pore structure and its application to sewage detection. For the first time the method of generating PVP-encapsulated Au NPs in aqueous solution is demonstrated. It was found that the formation of fluorescent Au NPs have highly fluorescent signal. Through the adsorption experiment, it is concluded that the methylene blue is adsorbed on Au NPs. This work successfully develops the capping PVP scaffolds of fluorescent Au NPs with pore structure. This experiment lays a foundation for the application of Au NPs in the field of environmental applications.
Hydrogenotrophic biogas upgrading integrated into WWTPs: enrichment strategy
Authors: Corbellini V. , Catenacci A. , Malpei F. 
Published: March 2019

AbstractWithin the European circular economy roadmap, it is important for wastewater treatment plant (WWTPs) to recover energy and become energy-neutral or -positive. In the last few years, it has become increasingly interesting to boost energy recovery through the biogas upgrading. The aim of this work is to study a rapid hydrogenotrophic methanogenic culture enrichment strategy capable of limiting the organic degradation unbalance and allowing a fast start-up phase of the in situ biogas upgrading reactors, at pilot- or full-scale. The approach was tested with two, plus one control, laboratory-scale continuous stirred tank reactors filled with anaerobic sludge collected from a full-scale WWTP. The experimentation lasted 50 days and was divided into five phases: the anaerobic digestion start-up followed by four H2 injection phases (H2/CO2 ranging from 1:1 to 4:1 on molar basis). Despite a temporary slight increase in the total concentration of volatile fatty acids during phase II (2.56 gCH3COOH·L−1), and in phase III a mild pH increase (anyway, below 7.4) indicating the expected CO2 depletion, the strategy proposed was effective. In the last phase, in the biogas a methane content of about 80% was achieved, thus suggesting that the use of H2/CO2 above the stoichiometric value could further improve the biological biogas upgrading.
Antidiabetic Activity of the Methanolic Extracts of Thuja occidentalis Twings in Alloxan-induced Rats
Authors: Tyagi C.K. , Porwal Pawan , Mishra Neeraj , Sharma Amit , Chandekar A. , Punekar R. , Punniyakoyi V.T. , Kumar Ajay , Anghore Durgadas 
Published: March 2019

Objective and Background:
In hyperglycemic and alloxan-induced diabetic rats,
the effect of Thuja occidentalis methanolic residue extract on blood glucose levels and some
biochemical parameters were investigated.

Methods:
Significantly decreased blood glucose level by 22.85% and 27.66%, in hyperglycemic
rats, respectively after 3 h, were seen in a single oral administration of the extract at a
dose of 200 and 400 mg/kg. Blood glucose level was decreased by 50% in alloxan-induced
diabetic rats within three weeks of daily treatment of Thuja occidentalis methanolic residue
extract (200 and 400 mg/kg p.o). Alloxan-induced diabetic rats showed significant hypercholesterolemia
in comparison with the control in alloxan induced rats.

Results:
In both normal and diabetic rats, there was also a significant decrease of elevated
serum cholesterol and triglycerides. Hypertriglyceridemia was also shown to be prevented
by treatment with plant extract (200 and 400mg/kg p.o) (p<0. 05). As compared with the
control animals, diabetic control rats did not show any change in a level of creatinine and
urea.

Conclusion:
Thuja occidentalis treatment may improve glucose homeostasis in alloxaninduced
diabetes and alleviate kidney and liver function. Thuja occidentalis twigs could be a
potential source of the new oral antidiabetic drug.
Si El Renacimiento tendía la mano, de El Libre Pensador asomaba el acero. Antagonismo en la República Restaurada
Authors: Mercado Noyola Francisco 
Published: March 2019

Este artículo expone las condiciones históricas que, durante la República Restaurada en México, dieron origen a un proyecto editorial como la revista El Renacimiento (1869), cuya consigna era acoger en su seno las producciones literarias de todas las plumas conspicuas del país, sin importar su filiación o pasado político. Este esfuerzo, liderado por Ignacio Manuel Altamirano, tuvo considerable cuórum por parte de los principales literatos, tanto liberales como conservadores. Un año más tarde, ante la virulencia del periódico católico La Voz de México, aparece El Libre Pensador. El presente trabajo pretende contrastar los textos y posturas de ambas publicaciones liberales.
INDEK KERENTANAN DAN AMPLIFIKASI TANAH AKIBAT GEMPA DI WILAYAH UNIVERSITAS MUHAMMADIYAH JEMBER
Authors: . Muhtar , Alihudien Arief 
Published: March 2019

INDEK KERENTANAN DAN AMPLIFIKASI TANAH AKIBAT GEMPA DI WILAYAH UNIVERSITAS MUHAMMADIYAH JEMBERVulnerability and Soil Amplification Index Due to Earthquake in The University Muhammadiyah JemberMuhtar1 & Arief Alihudien21Jurusan Teknik Sipil Fakultas Teknik – Universitas Muhammadiyah Jember2Jurusan Teknik Sipil Fakultas Teknik – Universitas Muhammadiyah JemberAlamat Korespondensi : Perum Taman Bambu B-01 Jember 68124Email : 1)muhtar.fitrah@gmail.comAbstractNatural phenomena of earthquakes until now could not be predicted and the exact time it happened. Earthquake danger can not be avoided but its impact can be reduced through assessment activities characteristic earthquakes in a region that will be applied in the selection of methods and policies for disaster risk management. Residential areas adjacent to the source of the earthquake is an earthquake-prone area so, therefore it is necessary strategic steps to protect the public and disaster mitigation measures are an attempt to reduce or minimize the impact of loss or damage that may be caused by the disaster. The study was conducted to provide information to the seismic vulnerability using multicriteria analysis of conditions in the region include University of Muhammadiyah Jember dominant period land values and the value of the amplification factor. The experiment was conducted using subsurface observation with mikrotremoR. From the results of geological studies research area is the basic constituent of igneous rocks such as tuff Argopuro. The results showed that the natural frequency of the soil and soil amplification is at 2,692 and 4,625 Hz. whereas soil vulnerability index value is equal to 7,946.Key Words : seismic, vulnerability, indexAbstrakFenomena alam gempa bumi sampai saat ini belum bisa diprediksi dan waktu yang tepat itu terjadi . Bahaya gempa tidak dapat dihindari namun dampaknya dapat dikurangi melalui kegiatan penilaian gempa bumi karakteristik di daerah yang akan diterapkan dalam pemilihan metode dan kebijakan untuk manajemen risiko bencana . Daerah pemukiman yang berdekatan dengan sumber gempa adalah daerah rawan gempa sehingga , oleh karena itu langkah-langkah strategis yang diperlukan untuk melindungi tindakan publik dan mitigasi bencana merupakan upaya untuk mengurangi atau meminimalkan dampak kerugian atau kerusakan yang mungkin disebabkan oleh bencana. Penelitian ini dilakukan untuk memberikan informasi kepada kerentanan seismik menggunakan analisis multikriteria kondisi di kawasan ini mencakup Universitas Muhammadiyah Jember nilai tanah periode dominan dan nilai faktor amplifikasi . Penelitian dilakukan dengan menggunakan observasi bawah permukaan dengan mikrotremoR. Dari hasil daerah penelitian studi geologi adalah konstituen dasar batuan beku seperti tuf Argopuro . Hasil penelitian menunjukkan bahwa frekuensi alami amplifikasi tanah dan tanah di 2,692 dan 4.625 Hz . sedangkan nilai indeks kerentanan tanah sama dengan 7946 .Kata Kunci : seismik , kerentanan , indeks
PENGARUH PEMBERIAN JUMLAH DAN RASIO (L/d) SERAT BENDRAT TERHADAP SIFAT MEKANIK BETON
Authors: Hafiz S.G Ahmad , Rommel Erwin , Prasetyo Lukito 
Published: March 2019

PENGARUH PEMBERIAN JUMLAH DAN RASIO (L/d) SERAT BENDRAT TERHADAP SIFAT MEKANIK BETONThe Influence of Steel Fiber Amount And L/D ratio to Mechanical Properties of ConcreteAhmad Hafiz S.G1, Erwin Rommel2, Lukito Prasetyo31 Staf Badan Perencana dan Pengembangan Kampus UMM2,3 Jurusan Teknik Sipil Universitas Muhammadiyah MalangAlamat korespondensi : email: erwin67pro@yahoo.com, ahafizsg16@gmail.com, prasetyo.lukito@gmail.comAbstractFiber concrete is the concrete which is mixed with fiber. The fiber was mixed into the concrete with the addition of fiber percentage. In this research, the fiber used was bendrat fiber. It had a diameter 0.8 mm which was cut be 1 cm, 2 cm, and 3 cm. Thus, the ratio (l/d) of fiber bendrat got 12,5 ; 25; and 37,5. Moreover, the amount of additional fiber used was 1 %, 2 % and 3 % from the amount of each cement ratio.In this research made 60 test concrete cylinder (150x300) mm in each of the 30 cylinder for testing compressive and 30 cylinders for testing tensile of the concrete. As for testing shear strength made 30 concrete specimen the shaped doubel-L (200x300x75) mm.The research results obtained that the wearing of a fiber ratio L/d = 12.5 will be able to enhance the tensile strength and shear stregth of concrete where fiber consumption bendrat as much as 3% obtained the greatest tensile strength 2,41 MPa or increased twice from the concrete without fibres, while for maximum shear strength reach 4,94 MPa with an increase of 54% compared to concrete without fibresKeywords: fiber concrete, steel fiber, tensile strength, shear strengthAbstrakBeton serat adalah bahan beton yang dicampur dengan serat dengan persentase tertentu. Dalam penelitian ini,serat yang digunakan adalah serat bendrat. Serat bendrat berdiamtere 0,8 mm dipotong-potong dengan panjang 1 cm, 2 cm dan 3 cm sehingga menghasilkan rasio L/d masing-masing 12,5; 25; dan 37,5. Sedangkan banyaknya serat yang ditambahkan terhadap volume berat yang digunakan masing-masing ; 1%, 2% dan 3%. Dalam penelitian dibuat 60 silinder diameter 150 mm dengan tinggi 300 mm masing-masing 30 silinder untuk pengujian tekan dan 30 silinder untuk pengujian tarik belah beton. Sedangkan untuk pengujian geser beton dibuat 30 specimen beton berbentuk doubel-L berukuran (200x300x75) mm. Hasil penelitian diperoleh bahwa pemakaian serat dengan rasio L/d=12,5 akan dapat meningkatkan kuat tarik dan kuat geser beton dimana pemakaian serat bendrat sebanyak 3% diperoleh kuat tarik terbesar 2,41 MPa atau meningkat 2 kali dari beton tanpa serat, sedangkan untuk kuat geser maksimal mencapai 4,94 MPa dengan kenaikan 54% dibandingkan dengan beton tanpa serat.Kata kunci : beton serat, serat bendrat, kuat tarik, kuat geser.
Redaksi dan Pedoman Penulisan Jurnal Media Teknik Sipil, Vol 13, No. 2, Agustus 2015
Authors: Pedoman Penulisan Redaksi & 
Published: March 2019

Redaksi dan Pedoman Penulisan Jurnal Media Teknik Sipil, Vol 13, No. 2, Agustus 2015ISSN 1693 - 3095PENGELOLAH “MEDIA TEKNIK SIPIL” JURUSAN TEKNIK SIPIL FAKULTAS TEKNIK UNIVERSITAS MUHAMMADIYAH MALANGVolume 13 Nomor 2, Agustus 2015Pembina : Dekan Fakultas TeknikPenanggung Jawab : Ketua JurusanPimpinan Redaksi : Ir. Erwin Rommel, MT.Tim Editor : 1. Dr. Ir. Sunarto, MT. 2. Dr. Ir. Samin, MT 3. Ir. Andi Saiful Amal, MT. 4. Rini Febri Utari, S.Pd., MT. Mitra Bestari : 1. Dr. Ir. Sri Sunarjono ( Universitas Muhammadiyah Surakarta) 2. Dr. Ir. Bambang Supriyadi, CES.DEA (Universitas Gajahmada) 3. Dr. Ing. Ir. Andreas Triwiyono 4. Dr. Ir. Ussy Andawayanti, MS 5. Herdin Prihantono, MT., PhD.Pelaksana Teknis : Apdani, S.Sos. Jurnal Media Teknik Sipil diterbitkan oleh Jurusan Teknik Sipil Fakultas Teknik Universitas Muhammadiyah Malang, secara berkala dengan terbit setiap bulan Februari dan Agustus, Redaksi “Media Teknik Sipil” menerima tulisan berupa artikel ilmiah dari praktisi, peneliti, akademisi, pemerhati keteknik sipilan secara luas. Untuk informasi lebih lanjut dapat ditanyakan kepada alamat redaksi. Alamat Redaksi Jurnal “Media Teknik Sipil”Jurusan Teknik Sipil Fakultas TeknikUniversitas Muhammadiyah MalangJln. Raya Tlogomas No.246 Malang 65144Telpon: (0341)464318130, Fax: (0341) 460782 E-mail : jurnal.sipil.umm@gmail.comhttp://ejournal.umm.ac.id/index.php/jmts/issue/archive