bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dégradation du cristal violet par électro-oxydation sur électrodes de Ti/TiO2 et Ti/TrO2-RuO2 : étude de l’influence des paramètres opératoires sur l’efficacité du procédé
Authors: Diouf Ibrahima , Drogui Patrick , Diop El Hadji Moussa , Lo Sidy Mambaye , Rumeau Michel , Mar Dop Codou Guèye 
Published: January 2019

Ce travail est une comparaison des capacités d’électro-oxydation du cristal violet sur des électrodes de Ti/TiO2 et Ti/IrO2-RuO2. Les résultats révèlent que le dépôt d’oxyde de métaux semi-conducteurs sur un support métallique adéquat tel que le titane permet d’améliorer l’activité électrochimique de ces électrodes. De même que l’influence des paramètres opératoires que sont la densité de courant (4,4, à 6,6 mA∙cm-2), la concentration de l’électrolyte (0,5 à 1,5 g∙L-1), la concentration initiale du colorant (2,5 x 10-5 à 10-4 M) et la surface d’électrode (4,55, 5,85 et 7,15 cm2) sur l’efficacité du traitement serait liée à la nature de l’électrode. Le suivi de la demande chimique en oxygène (DCO) au cours de l’électrolyse montre que Ti/IrO2-RuO2 possède le meilleur rendement épuratoire, puisqu’il permet d’atteindre un taux de réduction de la DCO de 92 % comparativement à un taux de 83 % enregistré dans le cas de Ti/TiO2 au bout de 2 h de traitement.
Kelpie: generating full-length ‘amplicons’ from whole-metagenome datasets
Authors: Greenfield Paul , Tran-Dinh Nai , Midgley David 
Published: January 2019

Introduction
Whole-metagenome sequencing can be a rich source of information about the structure and function of entire metagenomic communities, but getting accurate and reliable results from these datasets can be challenging. Analysis of these datasets is founded on the mapping of sequencing reads onto known genomic regions from known organisms, but short reads will often map equally well to multiple regions, and to multiple reference organisms. Assembling metagenomic datasets prior to mapping can generate much longer and more precisely mappable sequences but the presence of closely related organisms and highly conserved regions makes metagenomic assembly challenging, and some regions of particular interest can assemble poorly. One solution to these problems is to use specialised tools, such as Kelpie, that can accurately extract and assemble full-length sequences for defined genomic regions from whole-metagenome datasets.

Methods
Kelpie is a kMer-based tool that generates full-length amplicon-like sequences from whole-metagenome datasets. It takes a pair of primer sequences and a set of metagenomic reads, and uses a combination of kMer filtering, error correction and assembly techniques to construct sets of full-length inter-primer sequences.

Results
The effectiveness of Kelpie is demonstrated here through the extraction and assembly of full-length ribosomal marker gene regions, as this allows comparisons with conventional amplicon sequencing and published metagenomic benchmarks. The results show that the Kelpie-generated sequences and community profiles closely match those produced by amplicon sequencing, down to low abundance levels, and running Kelpie on the synthetic CAMI metagenomic benchmarking datasets shows similar high levels of both precision and recall.

Conclusions
Kelpie can be thought of as being somewhat like an in-silico PCR tool, taking a primer pair and producing the resulting ‘amplicons’ from a whole-metagenome dataset. Marker regions from the 16S rRNA gene were used here as an example because this allowed the overall accuracy of Kelpie to be evaluated through comparisons with other datasets, approaches and benchmarks. Kelpie is not limited to this application though, and can be used to extract and assemble any genomic region present in a whole metagenome dataset, as long as it is bound by a pairs of highly conserved primer sequences.
Brain lesion characteristics in Chinese multiple sclerosis patients: A 7‐T MRI cohort study
Authors: Su Lei , Zhang Zhe , Gao Chenyang , Guo Ai , Zhang Mengting , Shi Xiaoyu , Liu Xinyao , Song Tian , Xu Wangshu , Wang Huabing , Kuchling Joseph , Jing Jing , Tian De‐Cai , Liu Yaou , Duan Yunyun , Paul Friedemann , Shi Fu‐Dong 
Published: November 2024

AbstractObjectivePrevalence, susceptibility genes, and clinical and radiological features may differ across different ethnic groups of multiple sclerosis (MS). We aim to characterize brain lesions in Chinese patients with MS by use of 7‐T MRI.MethodsMS participants were enrolled from the ongoing China National Registry of Neuro‐Inflammatory Diseases (CNRID) cohort. 7‐T MRI of the brain was performed. Each lesion was evaluated according to a standardized procedure. Central vein sign (CVS) and paramagnetic rim lesions were identified. The characteristics of lesions at patient‐level and at lesion‐level from previous 7‐T MRI literature were also summarized.ResultsWe included 120 MS patients. Their mean (SD) age was 34.6 (9.4) years. The female‐to‐male ratio was 1.7:1 and mean disease duration of patients with MS was 5.5 ± 6.1 years. The median EDSS score was 2 (range, 0–8). A total of 8502 lesions were identified with a median lesion count of 45 (IQR, 18–90) (range, 2–370). The median (IQR) percentage for these special locations were as follows: cortical lesions (CLs) 2.7% (0%–5.7%), juxtacortical lesions 16.2% (7.8%–25.7%), periventricular lesions 30.2% (17.2%–38.7%), and infratentorial lesions 5.8% (0.4%–11.9%). CLs occurred in 70 (58%) patients, accounting for only 443 (5%) of the total lesions. Out of the 443 CLs, 309 (69.8%) were leukocortical lesions. CVS appeared in 5392 (63%) lesions from 117 (98%) patients. 1792 (21%) lesions and 104 (87%) patients exhibited a paramagnetic rim.InterpretationOur study elaborated on the lesion features of Chinese patients with MS by use of 7‐T MRI. Lesion burden is heavy in Chinese patients with MS. The median lesion count and proportion of PRL are high. The reported heavy lesion burden calls for ramping up regional and global efforts to care for MS patients. The management and research of Chinese population with MS needs to be further strengthened.
Revisiting the Link Between HLA‐DRB1 Alleles and Autoantibodies in Rheumatoid Arthritis: Association of non‐Shared Epitope Alleles *09 and *15 With High Levels of Anti–Citrullinated Peptide/Protein Antibodies
Authors: Lagutkin Denis , Panaifo Luis , Nurul‐Aain Ahmad‐Fauzi , Israelsson Lena , Hansson Monika , Lundberg Karin , Alfredsson Lars , Askling Johan ,   RACI consortium, Klareskog Lars , Too Chun‐Lai , Padyukov Leonid 
Published: November 2024

ObjectiveAutoantibodies serve as essential clinical biomarkers and may indicate etiological mechanisms in rheumatic diseases. In light of the increasing knowledge concerning the diversity and biologic implications of anti–citrullinated peptide/protein antibodies (ACPAs), we have re‐evaluated the association between the ACPA response and the HLA‐DRB1 allelic groups, known to represent a major genetic risk factor for rheumatoid arthritis (RA).MethodsWe explored a collection of 4,392 well‐characterized incident patients with RA of White European descent from the Epidemiological Investigation of Rheumatoid Arthritis (EIRA) new‐onset RA study, as well as 1,199 cases of patients with RA of Southeast Asian origin from the Malaysian EIRA study. We focused on a quantitative analysis of the levels of anti–cyclic citrullinated peptide IgG antibodies, including those falling below the diagnostic threshold.ResultsOur data show that non‐shared epitope alleles HLA‐DRB1*09 and *15 exhibit significant associations with ACPA levels. Notably, these novel associations were independent of ethnicity. To validate our findings, we conducted an additional replication study in an independent pool of 4,109 patients with RA of White European origin.ConclusionThese results indicate a new, previously overlooked, role for the HLA locus in the regulation of the levels of ACPA RA‐specific autoantibodies that goes beyond the shared epitope‐defined gene variants.
Directly Printable and Adhesive Liquid Metal Ink for Wearable Devices
Authors: Chen Wenfu , Tang Qianqiang , Zhong Weijie , Lai Mengnan , Shi Shiyang , Tan Jiqian , Luo Ziqing , Liu Xurui , Ye Zhicheng , He Rui , Jiang Fulong , Zhou Xuechang , Wang Ben 
Published: November 2024

AbstractLeveraging the fluidity and excellent conductivity of liquid metal (gallium‐indium alloy), liquid metal (LM) can be utilized to manufacture flexible and stretchable electronic products for applications in soft robotics, wearable devices, and human–machine interaction. However, the high surface tension and low surface adhesion of LM hinder its patterning and high‐resolution fabrication of soft electronics. Here a recyclable LM‐silicon dioxide (LMS) ink is proposed. Under stirring, silicon dioxide (SiO2) particles are encapsulated by the oxide layer of the LM, consuming the oxide layer. Meanwhile, gallium in the LM reacts with oxygen from the air to form a new oxide layer, enhancing the adhesion of the LM to the substrate while maintaining its conductivity. The in‐situ printing of LMS ink is verified on various materials (e.g., paper, polymer, and glass) with a resolution of up to 165 µm and an exceptional conductivity of ≈6.53 × 106 S m−1. The printed patterns can be erased with an anhydrous ethanol solution, allowing the recovered LMS ink to be reused for multiple writing cycles. The general method for direct LM circuits printing can fabricate various wearable sensors for soft electronic devices and human–machine interaction.
Advanced Aerodynamics‐Driven Energy Harvesting Leveraging Galloping‐Flutter Synergy
Authors: Dong Liwei , Hu Guobiao , Tang Qian , Zhao Chaoyang , Yang Fan , Yang Yaowen 
Published: November 2024

AbstractFlow‐induced vibrations (FIVs) serve as the fundamental principle of non‐rotary wind energy harvesting. However, nanogenerators relying on a single FIV effect remain constrained by insufficient breeze energy conversion efficiency. In this paper, we propose a novel galloping‐flutter coupled nanogenerator (GFNG) that leverages the synergistic interaction between these two aerodynamic phenomena, to achieve high performance across broad wind speed bandwidth. A galloping‐flutter coupled mechanism (GFM) is implemented using a multifunctional flexible beam that integrates a galloping piezoelectric energy harvester (GPEH) and a fluttering triboelectric nanogenerator (FTENG). Through meticulous optimization, it significantly enhances the average electrical output of the FTENG by up to six times at low wind speeds below 6 m s−1, by intensifying the triboelectric contact behavior through galloping‐induced beam oscillations. The GFNG demonstrates a maximum average power of 6.3 mW across wind speeds from 1.4 to 10 m s−1, along with a remarkable power density of 7.1 W m−2 of the enhanced FTENG at 10 m s−1, enabling the lighting of 508 LEDs and stable power supply for wireless sensor nodes (WSNs). This study offers new insights into designing high‐performance aerodynamics‐driven nanogenerators by harnessing multiple FIV synergistic effects, broadening the potential for intelligent wind energy applications.
Ultrasound‐Responsive Carbon Monoxide Microneedle for Enhanced Healing of Infected Diabetic Wounds
Authors: Cao Lei , Liu Chuang , Mu Chuan , Li Qingqing , Wu Min , Liu Luntao , Liu Bin 
Published: November 2024

AbstractEfficient management of difficult‐to‐heal diabetic wounds remains a clinical challenge owing to bacterial infections, as well as oxidative and hyperglycemic complex pathology. Therefore, developing intelligent strategies for diabetic wound healing is urgently needed. Herein, an ultrasound (US)‐responsive microneedle (MN) patch (MN@GOX@TiO2‐X@CO) capable of controlled delivery of carbon monoxide (CO) gas within the skin for effective treatment of diabetic infected wounds is developed. Benefiting from the specific form of microneedle (MN) patch, sonosensitizer (TiO2‐X), •OH‐responsive CO prodrug (MPA‐CO), and glucose oxidase (GOX) can be loaded together and effectively delivered to infectious wounds. With the semi‐fluidic hyaluronic acid (HA) coating under the physiological condition, CO could be released efficiently in situ and directly acted on infected wound tissue upon US triggering. Both in vitro and in vivo results showed that US‐triggered CO release from MN@GOX@TiO2‐X@CO not only effectively inhibited the S. aureus and MRSA infection but also promoted fibroblasts proliferation and migration under hyperglycemic physiology, thereby accelerating diabetic wound healing. Collectively, the approach effectively addresses the impaired skin regeneration function in diabetic wounds and offers a promising therapeutic strategy for the efficient healing of infected diabetic wounds.
Near‐Infrared Bioimaging Using Two‐photon Fluorescent Probes
Authors: Pragti  , Kundu Bidyut Kumar , Chen Rui , Diao Jiajie , Sun Yujie 
Published: November 2024

AbstractNear‐infrared (NIR) bioimaging has emerged as a transformative technology in biomedical research. Among many fluorescent probes that are suitable for NIR imaging studies, two‐photon absorption (TPA) ones represent a particularly promising category, because TPA fluorescent probes can overcome the inherent limitations of one‐photon absorption (OPA) counterparts. By leveraging the unique properties of two‐photon absorption, TPA fluorescent probes achieve superior tissue penetration, significantly reduced photodamage, and enhanced spatial resolution. This perspective article delves into the fundamental principles, design strategies, and representative TPA probes for various imaging applications. In particular, a number of molecular fluorescent probes, ranging from organic, inorganic, and COF/MOF‐based systems are highlighted to showcase the vast scope of possible TPA probe design and application scenarios. In addition, the employment of stimulated TPA probes that are responsive to different external factors, including pH, redox species, enzymes, and hypoxia, is also discussed. In the end, the future perspectives for the continuous advancement of TPA fluorescent probes in the NIR bioimaging field are presented. For instance, it is essential to transition from cellular to in vivo imaging studies to obtain more physiologically relevant insights. Additionally, the development of “dual‐function” TPA probes for both disease diagnosis and therapeutic treatment is particularly promising.
Efficient PFAS Removal Using Reusable and Non‐Toxic 3D Printed Porous Trianglamine Hydrogels
Authors: Chaix Arnaud , Gomri Chaimaa , Benkhaled Belkacem Tarek , Habib Michel , Dupuis Romain , Petit Eddy , Richard Jason , Segala Antonin , Lichon Laure , Nguyen Christophe , Gary‐Bobo Magali , Blanquer Sébastien , Semsarilar Mona 
Published: November 2024

AbstractPer‐ and polyfluoroalkyl substances (PFAS) are now a paramount concern in water remediation. Nowadays, urgent action is required for the development of advanced technologies aimed at capturing PFAS and mitigating their impact. To offer a solution, a functional 3D printed hydrogel tailored is designed to trap a broad spectrum of PFAS contaminants. The hydrogel is made of a photo‐crosslinked dimethacrylate‐ureido‐trianglamine (DMU‐Δ) and Pluronic P123 dimethacrylate (PDM) fabricated by stereolithography (SLA). With the aid of 3D‐printing, porous and nonporous hydrogels (3D‐PSHΔ, 3D‐SHΔ) as well as quaternized hydrogels (3D‐PSHΔQ+) are prepared. These tailored hydrogels, show high uptake capacities and fast removal kinetics for PFAS from aqueous sources. The PFAS removal efficiency of these hydrogels are then compared to P123 hydrogels with no trianglamine (3D‐SH). The 3D‐SH hydrogel shows no affinity to PFAS, proving that the sorption is due to the interaction between the trianglamine (Δ) and PFAS. Metadynamic simulations also confirmed this interaction. The porous matrices showed the fastest and highest uptake capacity. 3D‐PSHΔ is able to capture ≈ 91% of PFAS within 5 h using initial concentrations of 5 and 0.5 ppm in both deionized and river water. The sorption of PFAS is further enhanced by introducing permanent positive charges to the structure of the porous hydrogels, resulting in even faster sorption kinetics for both long and short PFAS chains with diverse polar heads. Besides the remarkable efficiency in capturing PFAS, these designed hydrogels are non‐toxic and have outstanding chemical and thermal stability, making them a brilliant candidate for mass use in the combat against PFAS pollution.
Upper Layer‐Modulated Pseudo Planar Heterojunction with Metal Complex Acceptor for Efficient and Stable Organic Photovoltaics
Authors: Luo Dou , Zhang Lifu , Zeng Jie , Zhang Hongyang , Li Lanqing , Dai Tingting , Xu Baomin , Zhou Erjun , Kyaw Aung Ko Ko , Chen Yiwang , Wong Wai‐Yeung 
Published: November 2024

AbstractModulating self‐aggregation and charge transport in the upper acceptor layer of the pseudo planar heterojunction (PPHJ) is crucial for enhancing dielectric constant and suppressing trap density, leading to efficient and stable organic photovoltaics (OPVs). In this work, a metal complex acceptor (MCA), PtAC‐Cl, is selectively incorporated into the upper host Y6 layer of PPHJ to regulate morphology and fill trap states. There exists a strong chemical interaction between PtAC‐Cl and Y6, which can promote electron transfer. PtAC‐Cl can regulate the self‐aggregation and extend the exciton diffusion length of Y6, resulting in enhanced charge transport and reduced energetic disorder. Consequently, upper layer‐modulated PPHJ devices with PtAC‐Cl achieved a significant power conversion efficiency of 18.16%. The universality of PtAC‐Cl is also demonstrated in PM6/eC9 and PM6/L8‐BO systems, achieving the highest PCEs of 18.79 and 19.30%, respectively. All the improved PCEs are mainly attributed to the enhanced fill factor (FF) and short circuit current (Jsc) compared with the controls. Additionally, PtAC‐Cl significantly improves the thermal stability and photostability of the devices, with a T80 lifetime of ≈ 401 h under continuous illumination with simulated 1‐Sun light and 1265 h under continuous heating at 70 °C. Overall, this work introduces the concept of MCA and proposes a practical and efficient method to enhance the efficiency and stability of OPVs through selective upper‐layer modulation in PPHJ with MCA.
Dual‐Function Self‐Assembled Molecules as Hole‐Transport Layers for Thermally Evaporated High‐Efficiency Blue Perovskite Light‐Emitting Diodes
Authors: Chen Ben , Peng Chencheng , Guo Runda , He Zhiyuan , Sun Liang , Zhang Feihu , He Xiping , Zeng Haibo , Wang Lei 
Published: November 2024

AbstractThermally evaporated perovskite light‐emitting diodes (PeLEDs) hold immense potential for future applications in the display industry. However, the performance of blue PeLEDs is far behind, one of the most important reasons is the lack of suitable hole‐transporting materials. Herein, the study designs and synthesizes a new class of self‐assembled monolayer (SAM) materials, namely, (2‐(3,6‐bis(4‐formylphenyl)‐9H‐carbazol‐9‐yl)ethyl)phosphonic acid (C‐2PACz) and (2‐(3,6‐bis(4‐(methylsulfonyl)phenyl)‐9H‐carbazol‐9‐yl)ethyl)phosphonic acid (S‐2PACz). First, the phosphonic acid is induced to form bidentate bonds with ITO. Second, the strong electron‐withdrawing groups are integrated to increase the electron cloud density of the termini contacting with perovskite, which enhances the electrostatic interaction with the Pb2+, reduces the interfacial defects. These advantages improve their carrier transport ability and reduce the non‐radiative recombination at the interface. Meanwhile, it is found that compound C‐2PACz possessing the smaller steric hindrance makes the SAMs have a more homogeneous film and a better interfacial passivation effect. By employing C‐2PACz as hole‐transporting layer in blue PeLEDs with metal halides as the emitting layer, the device exhibits a high brightness (1843 cd m−2) and a maximum external quantum efficiency (10.41% @65.59 cd m−2), which among the best of reported thermally evaporated sky‐blue PeLEDs. The work provides new insights into design strategies for dual‐function SAMs to achieve higher performance in PeLEDs.
High Thermal Conductive Crystalline Organohalide for Endurable Resistive Switching Non‐Volatile Memory
Authors: Lee Joo‐Hong , Jung Sung‐Kwang , Kim Gimoon , Park Ji‐Sang , Park Keonwoo , Yang Cheol‐Woong , Lee Jin‐Wook 
Published: November 2024

AbstractThe organic‐based memristive devices are widely studied as a next‐generation electronics for eco‐friendly wearable applications, thanks to materials` flexibility and biocompatibility. However, poor operational reliability and stability of the devices remain a critical challenge. Here, the study demonstrates a crystalline organohalide, Dabconium ammonium triiodide (DABCO‐NH4‐I3, DABCO is 1,4‐diazabicyclo[2.2.2] octonium)‐based memristive device with exceptionally high reliability and endurance. Owing to the low dielectric constant and anisotropic hexagonal crystal structure consisting of hydrogen bonds with a high bandgap, the DABCO‐NH4‐I3‐based conductive bridging random access memory device demonstrates millivolt‐scale operating voltages with a remarkably high on/off ratio of ≈109, capable of multi‐level storage. The relatively higher thermal conductivity of the crystalline organohalide (1.06 W m−1K−1), compared to most of organic materials (0.1–0.5 W m−1K−1), is found to be beneficial to suppress intense heat accumulation generated by Joule heating effect during device operation. With the facilitated dissipation of the generated heat, the simple planar heterojunction structured device shows remarkably endurable resistive switching over 103 cycles of program‐erase at both room temperature and 85 °C with high switching reliability. This study introduced a new class of materials that can overcome the limitations of existing organic materials for high‐performance next‐generation organic electronic devices.
Atomic‐Scale Insights Into the Thermal Stability of High‐Entropy Nanoalloys
Authors: Krouna Syrine , Acheche Anissa , Wang Guillaume , Pena Nathaly Ortiz , Gatti Riccardo , Ricolleau Christian , Amara Hakim , Nelayah Jaysen , Alloyeau Damien 
Published: November 2024

AbstractHigh entropy alloy nanoparticles bring hope to developing more efficient nanomaterials for high‐temperature applications. Nevertheless, the enhanced thermal stability of nearly equiatomic nanoalloys containing at least 5 metals is nothing more than theoretical speculation about the impact of thermodynamic contributions on their structural properties and remains to be proven. Here, in situ aberration‐corrected scanning transmission electron microscopy (STEM) and molecular dynamics simulations are combined to investigate at the atomic scale the thermal behavior of AuCoCuNiPt nanoparticles (NPs) from 298 to 973 K. Both in situ STEM heating and atomistic simulations reveal strong structural and chemical evolutions in the NPs with the formation and melting of an AuCu layer at the surface of NPs at high temperature. This phase separation that appears progressively with temperature is driven by pronounced atomic diffusion that is surprisingly more active in these quinary nanoalloys than in monometallic and bimetallic subsystems. Besides ruling out the existence of sluggish diffusion in AuCoCuNiPt nanoalloys and lowering their temperature range of application, the study allows distinguishing kinetic and thermodynamic effects on their structural properties, which is an essential prerequisite to better control the synthesis of complex nanomaterials.