bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing reputation measurement: evolving toward improved quantitative assessments
Authors: Horn Richard , Wagner Ralf 
Published: August 2019

Purpose
The purpose of this paper is to provide evidence on the information-gathering deficits in contemporary reputation measurement that are rooted in sampling and to obtain supporting information from respondents from various stakeholder groups.

Design/methodology/approach
In regard to social emergence theory, the authors examine the common practice of aggregating reputational judgments from randomly sampled respondents without considering their knowledge domains. A stereotyping experiment conducted in three countries provides evidence that lower-level reputations might vary, whereas higher-level reputations resulting from the social emergence process do not vary.

Findings
The findings demonstrate that researchers should consider respondents’ heterogeneity in regard to reputation measurement. Stakeholder judgments divergent from their domains of expertise often add noise, instead of informative answers, to the reputational categories.

Research limitations/implications
The social emergence process, in addition to the roles of the stakeholders, their interaction structures and the timing of their communication, needs to be incorporated into an improved reputation measurement method.

Practical implications
Not all information from the same respondent should be considered when computing a final reputation score. Respondents’ heterogeneity is revealed to be fundamental for reputational assessments.

Originality/value
This study is original in its examination of the validity of reputation assessment being restricted to lower-level descriptions of the supervenience relation. Building upon the results of the experiment conducted in three national framings, this paper suggests ways to improve reputation measurement.
Effect of print orientation on microstructural features and mechanical properties of 3D porous structures printed with continuous digital light processing
Authors: Navarro Javier , Din Matthew , Janes Morgan Elizabeth , Swayambunathan Jay , Fisher John P. , Dreher Maureen L. 
Published: August 2019

Purpose
This paper aims to study the effects of part orientation during the 3D printing process, particularly to the case of using continuous digital light processing (cDLP) technology.

Design/methodology/approach
The effects of print orientation on the print accuracy of microstructural features were assessed using microCT imaging and mechanical properties of cDLP microporous scaffolds were characterized under simple compression and complex biaxial loading. Resin viscosity was also quantified to incorporate this factor in the printing discussion.

Findings
The combined effect of print resin viscosity and the orientation and spacing of pores within the structure alters how uncrosslinked resin flows within the construct during cDLP printing. Microstructural features in horizontally printed structures exhibited greater agreement to the design dimensions than vertically printed constructs. While cDLP technologies have the potential to produce mechanically isotropic solid constructs because of bond homogeneity, the effect of print orientation on microstructural feature sizes can result in structurally anisotropic porous constructs.

Originality/value
This work is useful to elucidate on the specific capabilities of 3D printing cDLP technology. The orientation of the part can be used to optimize the printing process, directly altering parameters such as the supporting structures required, print time, layering, shrinkage or surface roughness. This study further detailed the effects on the mechanical properties and the print accuracy of the printed scaffolds.
Climate change and women in South Asia: a review and future policy implications
Authors: Patel Sangram Kishor , Agrawal Gopal , Mathew Bincy , Patel Sunita , Mohanty Biswajit , Singh Abhishek 
Published: August 2019

PurposeSouth Asian region is a focal point owing to its vulnerabilities to climate-sensitive diseases, dependence on climate-sensitive livelihoods, projected levels of crop decline in the region, and high rates of poverty and malnutrition. Women are particularly vulnerable to climate change and this affects women disproportionately during different extreme events. The purpose of this paper is to understand the issue of climate change and its impact, and climate resilience among women in South Asia. Further, it also identifies the gaps and suggests future policy implications.Design/methodology/approachClimate change is increasingly being recognised as an alarming issue and the present review is important when South Asian countries are facing the brunt of climate change impacts. This paper tries to understand the issue by review of the literature and conceptual framework methodology. To understand women’s vulnerability due to climate change and its aftermath, the authors conducted both offline and online desk reviews for this study.FindingsThe findings of this study show a clear linkage between climate change and women’s vulnerabilities in South Asia. Climate change has significant socio-economic impacts on women, and it affects them disproportionately in various domains of agriculture, livelihood, food security, both physical and mental health, water and sanitation in the South Asia region.Practical implicationsThe paper also highlights that the programmes that aim at combating the effects of climate change require a gender-sensitive approach so that climate change does not obstruct the development and reduction of poverty in the region.Social implicationsThe findings of this paper will add value in helping families to come out of poverty by undertaking adaptive measures with proactive assistance from the government and grassroots level organisations.Originality/valueThe present study also advocates for more gender- and climate-sensitive measures from governments, and implementation of intervention- and evidence-based research in the South Asian countries.
Breadth of the thermal response captures individual and geographic variation in temperature‐dependent sex determination
Authors: Carter Anna L. , Bodensteiner Brooke L. , Iverson John B. , Milne‐Zelman Carrie L. , Mitchell Timothy S. , Refsnider Jeanine M. , Warner Daniel A. , Janzen Fredric J. 
Published: August 2019

Abstract

Population‐scale responses of key ecological traits to local environmental conditions provide insight into their adaptive potential. In species with temperature‐dependent sex determination (TSD), short‐term, individual developmental responses to the incubation environment have long‐term consequences for populations.

We took a model‐based approach to study within‐ and among‐population variation in the physiological components of TSD in 12 populations of painted turtles (Chrysemys picta). We used laboratory and field incubation data to quantify variation in thermal reaction norms at both population and clutch scales, focusing on the pivotal temperature that produces a 1:1 sex ratio (P) and the transitional range of incubation temperatures (TRTs) that produce mixed sex ratios.

Defying theoretical expectations, among‐population variation in P was not convincingly explained by geography or local thermal conditions. However, within some populations, P varied by >5°C at the clutch scale, indicating that the temperature sensitivity of gonadal differentiation can vary substantially among individual nesting females. In addition, the TRT was wider at lower latitudes, suggesting responsiveness to local incubation conditions.

Our results provide a potential explanation for discrepancies observed between constant‐temperature experimental results and outcomes of fluctuating incubation conditions experienced in natural nests, exposing important knowledge gaps in our understanding of local adaptation in TSD and identifying shortcomings of traditional laboratory studies. Understanding individual variation and the timing of gonadal differentiation is likely to be far more useful in understanding local adaptation than previously acknowledged.

A free Plain Language Summary can be found within the Supporting Information of this article.
Resistance of the oyster pathogen Vibrio tasmaniensis LGP32 against grazing by Vannella sp. marine amoeba involves Vsm and CopA virulence factors
Authors: Robino Etienne , Poirier Aurore C. , Amraoui Hajar , Le Bissonnais Sandra , Perret Angélique , Lopez‐Joven Carmen , Auguet Jean‐Christophe , Rubio Tristan P. , Cazevieille Chantal , Rolland Jean‐Luc , Héchard Yann , Destoumieux‐Garzón Delphine , Charrière Guillaume M. 
Published: August 2019

SummaryVibrios are ubiquitous in marine environments and opportunistically colonize a broad range of hosts. Strains of Vibrio tasmaniensis present in oyster farms can thrive in oysters during juvenile mortality events and behave as facultative intracellular pathogen of oyster haemocytes. Herein, we wondered whether V. tasmaniensis LGP32 resistance to phagocytosis is specific to oyster immune cells or contributes to resistance to other phagocytes, like marine amoebae. To address this question, we developed an integrative study, from the first description of amoeba diversity in oyster farms to the characterization of LGP32 interactions with amoebae. An isolate of the Vannella genus, Vannella sp. AP1411, which was collected from oyster farms, is ubiquitous, and belongs to one clade of Vannella that could be found associated with Vibrionaceae. LGP32 was shown to be resistant to grazing by Vannella sp. AP1411 and this phenotype depends on some previously identified virulence factors: secreted metalloprotease Vsm and copper efflux p‐ATPase CopA, which act at different steps during amoeba–vibrio interactions, whereas some other virulence factors were not involved. Altogether, our work indicates that some virulence factors can be involved in multi‐host interactions of V. tasmaniensis ranging from protozoans to metazoans, potentially favouring their opportunistic behaviour.
Advertising, Earnings Prediction and Market Value: An Analysis of Persistent UK Advertisers
Authors: Shah Syed Zulfiqar Ali , Akbar Saeed , Ahmad Sardar , Stark Andrew W. 
Published: August 2019

AbstractThis paper examines whether major media advertising expenditures help in predicting future earnings. We consider the role of media advertising in firms’ marketing efforts and posit that persistent advertisers are more likely to benefit from advertising activities in creating long‐lived intangible assets. Employing a sample of persistent UK advertisers over the period 1997–2013, we find that advertising expenditures are significantly positively associated with firms’ future earnings and market value. We also report size and sector‐based differences in the association between advertising and firms’ future earnings. Our additional analysis provides support for the arguments that despite the recent rise in digital advertising budgets, traditional advertising media are still effective in positively influencing firms’ performance. Overall, the results of this study are consistent with the view that advertising expenditures produce intangible assets, at least for firms in certain sectors. These findings have implications for marketers in providing evidence of the value generated by firms’ advertising budgets, for investors in validating the relevance of advertising information in influencing future earnings, and for accounting regulators in relation to the provision of useful insights for any future deliberations on financial reporting policies for advertising expenditures.
Association between maternal alcohol consumption during pregnancy and risk of preterm delivery: the Japan Environment and Children's Study
Authors: Ikehara S , Kimura T , Kakigano A , Sato T , Iso H ,   the Japan Environment Children's Study Group
Published: August 2019

ObjectiveTo examine the association between maternal alcohol consumption during pregnancy and the risk of preterm delivery.DesignProspective cohort study.SettingThe Japan Environment and Children's Study (JECS).PopulationA total of 94 349 singleton pregnancies.MethodsParticipants completed questionnaires detailing alcohol consumption during the first trimester and during the second and third trimesters. Participants were divided into four categories according to alcohol consumption (non‐drinkers, consumers of 1–149 g, 150–299 g and ≥300 g ethanol/week). We examined the effect of alcohol consumption during different stages of pregnancy on the risk of preterm delivery. Odds ratios (OR) and 95% CI were calculated relative to non‐drinkers using logistic regression.Main outcome measuresMedical record‐based preterm delivery.ResultsAlcohol consumption during the second and third trimesters, but not during the first trimester, was associated with increased risk of preterm delivery. Heavy alcohol consumption (≥300 g ethanol/week) during the second and third trimesters was associated with a four‐fold higher risk compared with non‐drinkers (multivariable OR 4.52; 95% CI 1.68–12.2). Light alcohol consumption (1–149 g ethanol/week) tended to be associated with lower risk of preterm delivery (multivariable OR 0.78; 95% CI 0.60–1.00).ConclusionsHeavy alcohol consumption during the second and third trimesters was associated with increased risk of preterm delivery among pregnant women.Tweetable abstractHeavy drinking during pregnancy may increase the risk of preterm delivery.
Trends in Substance Use by Gender Among Participants in a Jail‐Based Substance Use Disorder Treatment Program: 1998–2016
Authors: Bello Jennifer K. , Hearing Catherine , Salas Joanne , Weinstock Jeremiah , Linhorst Donald 
Published: August 2019

AbstractUnderstanding trends in substance use by gender among jail‐based treatment program participants can inform policies and programs tailored to this population. Preprogram assessment data from 3509 individuals entering a jail‐based substance use disorder treatment program in Missouri between 1998 and 2016 were analyzed. Primary outcome was program participants’ strongly preferred substances. Demographic covariates and drug preferences were compared between males and females. Average yearly trends in preferred substances were calculated. While 25.8% of the sample preferred heroin, it was more strongly preferred by women (36.4%) than men (22.0%, p < 0.0001). Alcohol and marijuana were preferred more by males. Overall, preferences for heroin and methamphetamine increased over time while alcohol, marijuana, and other stimulants decreased. Women being more likely to prefer heroin and the increasing preference for heroin over time are consistent with national trends. Offering evidence‐based treatment like pharmacotherapy and gender‐sensitive approaches can help address the needs of this vulnerable population.
Harnessing biocompatible chemistry for developing improved and novel microbial cell factories
Authors: Liu Jian‐Ming , Solem Christian , Jensen Peter Ruhdal 
Published: August 2019

SummaryWhite biotechnology relies on the sophisticated chemical machinery inside living cells for producing a broad range of useful compounds in a sustainable and environmentally friendly way. However, despite the impressive repertoire of compounds that can be generated using white biotechnology, this approach cannot currently fully replace traditional chemical production, often relying on petroleum as a raw material. One challenge is the limited number of chemical transformations taking place in living organisms. Biocompatible chemistry, that is non‐enzymatic chemical reactions taking place under mild conditions compatible with living organisms, could provide a solution. Biocompatible chemistry is not a novel invention, and has since long been used by living organisms. Examples include Fenton chemistry, used by microorganisms for degrading plant materials, and manganese or ketoacids dependent chemistry used for detoxifying reactive oxygen species. However, harnessing biocompatible chemistry for expanding the chemical repertoire of living cells is a relatively novel approach within white biotechnology, and it could potentially be used for producing valuable compounds which living organisms otherwise are not able to generate. In this mini review, we discuss such applications of biocompatible chemistry, and clarify the potential that lies in using biocompatible chemistry in conjunction with metabolically engineered cell factories for cheap substrate utilization, improved cell physiology, efficient pathway construction and novel chemicals production.
A Personal View of the Evolution of the Accounting Professoriate
Authors: Zeff Stephen A. 
Published: August 2019

ABSTRACTThe first three‐quarters of this paper are a review and analysis of the evolution of the accounting research environment, primarily in the United States but also with respect to Canada, from the 1960s to the present time. The final quarter of the paper consists of a critique of contemporary approaches to accounting research as well as recommendations for reform.
Late‐onset retinal degeneration pathology due to mutations in CTRP5 is mediated through HTRA1
Authors: Chekuri Anil , Zientara‐Rytter Katarzyna , Soto‐Hermida Angel , Borooah Shyamanga , Voronchikhina Marina , Biswas Pooja , Kumar Virender , Goodsell David , Hayward Caroline , Shaw Peter , Stanton Chloe , Garland Donita , Subramani Suresh , Ayyagari Radha 
Published: August 2019

AbstractLate‐onset retinal degeneration (L‐ORD) is an autosomal dominant macular degeneration characterized by the formation of sub‐retinal pigment epithelium (RPE) deposits and neuroretinal atrophy. L‐ORD results from mutations in the C1q‐tumor necrosis factor‐5 protein (CTRP5), encoded by the CTRP5/C1QTNF5 gene. To understand the mechanism underlying L‐ORD pathology, we used a human cDNA library yeast two‐hybrid screen to identify interacting partners of CTRP5. Additionally, we analyzed the Bruch's membrane/choroid (BM‐Ch) from wild‐type (Wt), heterozygous S163R Ctrp5 mutation knock‐in (Ctrp5S163R/wt), and homozygous knock‐in (Ctrp5S163R/S163R) mice using mass spectrometry. Both approaches showed an association between CTRP5 and HTRA1 via its C‐terminal PDZ‐binding motif, stimulation of the HTRA1 protease activity by CTRP5, and CTRP5 serving as an HTRA1 substrate. The S163R‐CTRP5 protein also binds to HTRA1 but is resistant to HTRA1‐mediated cleavage. Immunohistochemistry and proteomic analysis showed significant accumulation of CTRP5 and HTRA1 in BM‐Ch of Ctrp5S163R/S163R and Ctrp5S163R/wt mice compared with Wt. Additional extracellular matrix (ECM) components that are HTRA1 substrates also accumulated in these mice. These results implicate HTRA1 and its interaction with CTRP5 in L‐ORD pathology.
A serum protein signature of APOE genotypes in centenarians
Authors: Sebastiani Paola , Monti Stefano , Morris Melody , Gurinovich Anastasia , Toshiko Tanaka , Andersen Stacy L. , Sweigart Benjamin , Ferrucci Luigi , Jennings Lori L. , Glass David J. , Perls Thomas T. 
Published: August 2019

AbstractThe discovery of treatments to prevent or delay dementia and Alzheimer's disease is a priority. The gene APOE is associated with cognitive change and late‐onset Alzheimer's disease, and epidemiological studies have provided strong evidence that the e2 allele of APOE has a neuroprotective effect, it is associated with increased longevity and an extended healthy lifespan in centenarians. In this study, we correlated APOE genotype data of 222 participants of the New England Centenarian Study, including 75 centenarians, 82 centenarian offspring, and 65 controls, comprising 55 carriers of APOE e2, with aptamer‐based serum proteomics (SomaLogic technology) of 4,785 human proteins corresponding to 4,137 genes. We discovered a signature of 16 proteins that associated with different APOE genotypes and replicated the signature in three independent studies. We also show that the protein signature tracks with gene expression profiles in brains of late‐onset Alzheimer's disease versus healthy controls. Finally, we show that seven of these proteins correlate with cognitive function patterns in longitudinally collected data. This analysis in particular suggests that Baculoviral IAP repeat containing two (BIRC2) is a novel biomarker of neuroprotection that associates with the neuroprotective allele of APOE. Therefore, targeting APOE e2 molecularly may preserve cognitive function.
NOP Receptor Antagonists Decrease Alcohol Drinking in the Dark in C57BL/6J Mice
Authors: Brunori Gloria , Weger Michelle , Schoch Jennifer , Targowska‐Duda Katarzyna , Barnes Megan , Borruto Anna Maria , Rorick‐Kehn Linda M. , Zaveri Nurulain T. , Pintar John E. , Ciccocioppo Roberto , Toll Lawrence , Cippitelli Andrea 
Published: August 2019

BackgroundThe nociceptin/orphanin FQ opioid peptide (NOP) receptor and its endogenous ligand N/OFQ have been implicated in the regulation of drug and alcohol use disorders (AUD). In particular, evidence demonstrated that NOP receptor activation blocks reinforcing and motivating effects of alcohol across a range of behavioral measures, including alcohol intake, conditioned place preference, and vulnerability to relapse.MethodsHere, we show the effects of pharmacological activation and inhibition of NOP receptors on binge‐like alcohol consumption, as measured by the “drinking in the dark” (DID) model in C57BL/6J mice.ResultsWe found that 2 potent and selective NOP agonists AT‐202 (0, 0.3, 1, 3 mg/kg) and AT‐312 (0, 0.3, 1 mg/kg) did not affect binge alcohol drinking at doses that do not affect locomotor activity. AT‐202 also failed to alter DID behavior when administered to mice previously exposed to chronic alcohol treatment with an alcohol‐containing liquid diet. Conversely, treatment with either the high affinity NOP receptor antagonist SB‐612111 (0, 3, 10, 30 mg/kg) or the selective antagonist LY2817412 (0, 3, 10, 30 mg/kg) decreased binge drinking. SB‐612111 was effective at all doses examined, and LY2817412 was effective at 30 mg/kg. Consistently, NOP receptor knockout mice consumed less alcohol compared to wild type. SB‐612111 reduced DID and increased sucrose consumption at doses that do not appear to affect locomotor activity. However, the high dose of SB‐612111 (30 mg/kg) reduced alcohol intake but failed to inhibit preference in a 2‐bottle choice DID model that can assess moderate alcohol intake.ConclusionsThe present results suggest that NOP receptor inhibition rather than activation may represent a valuable approach for treatment of AUD characterized by excessive alcohol consumption such as binge drinking.