bluuebunny/crossref_metadata_2025_split huggingface dataset:
The well-being of software engineers: a systematic literature review and a theory
Authors: Godliauskas Povilas , Šmite Darja 
Published: December 2024

Abstract
For decades, software engineering research and practice has focused primarily on technological and process-related factors. Today, there is a growing interest in organizational, social, and psychological factors, including well-being. Organizational studies show that well-being contributes to work outcomes, including creativity, performance, and productivity. But despite its importance, the predictors and outcomes of software engineers’ well-being as a multidimensional construct to date are under-researched. This paper reports on the multidimensional well-being of professional software engineers and generates insights for the future research in this area. 44 quantitative survey studies published between 2000 and 2023 were selected and synthesized both quantitatively and qualitatively through a systematic literature review. The results of the review were further analyzed to construct a quantitatively-testable theory, detailing the predictors and outcomes of well-being in software engineering organizations. The total number of research participants included in the selected studies is 16,086 software engineering professionals from at least 42 countries. The literature review identified various measures, constructs, and indicators of well-being, as well as its predictors and outcomes. The theory, based on cumulative results of carefully selected quantitative studies, is an attempt to “correct the record” by establishing well-being in software engineering as a meta-construct of hedonic, eudaimonic, and integrated or hedaimonic qualities predicted by different individual, team and organizational factors and impacting the functioning of software engineers and their organizations. The review highlighted the under-researched aspects of well-being in software engineering and confirmed the need for more advanced quantitative studies. We hope that the theory will benefit researchers in conducting future studies and practitioners in developing nuanced and science-based interventions for improving software engineers’ well-being.
A Propositional Cirquent Calculus for Computability Logic
Authors: Japaridze Giorgi 
Published: December 2024

AbstractCirquent calculus is a proof system with inherent ability to account for sharing subcomponents in logical expressions. Within its framework, this article constructs an axiomatization $$\text{ CL18 }$$

CL18

of the basic propositional fragment of computability logic—the game-semantically conceived logic of computational resources and tasks. The nonlogical atoms of this fragment represent arbitrary so called static games, and the connectives of its logical vocabulary are negation and the parallel and choice versions of conjunction and disjunction. The main technical result of the article is a proof of the soundness and completeness of $$\text{ CL18 }$$

CL18

with respect to the semantics of computability logic.
The effect of the increased strain per pass during the hot-rolling and its effect on the tensile properties of V-Mo and Cr-V-Mo microalloyed dual-phase steels
Authors: Rodriguez-Galeano Karol F. , Nutter John , Azakli Yunus , Slater Carl , Rainforth W. Mark 
Published: December 2024

AbstractIt is well known that the thermomechanical processing parameters affect the mechanical properties of dual-phase (DP) steels, but optimization still remains a key challenge. This work studied two interphase precipitation-strengthened DP steels based on V, Mo, and V, Mo, Cr microalloy additions. Hot-rolling was performed with a strain per pass of 0.2 and 0.4 before isothermal transformation at temperatures between 600 and 690 °C to determine the effect of these process parameters on microstructure, particularly interphase precipitation. The microstructure was carefully correlated with the mechanical properties. It was found that a higher strain during hot rolling increases the transformation kinetics of austenite to ferrite and also increases the volume fraction of the interphase precipitation within it, leading to higher strength values. The reaustenitization temperature before the isothermal transformation also plays an important role, with increased temperature reducing the segregation banding effect and increasing the amount of ferrite. The optimal reaustenitization temperature depends on the composition, being 1250 °C for the microalloyed steel with Cr additions and 1150 °C for the Cr-free microalloyed steel. A new method was used to calculate the yield strength of these DP microalloyed steels, including the strengthening contributors of each phase and the banding effect brought into one single expression that matches the experimental results.
Blood-based biomarkers for early frailty are sex-specific: validation of a combined in silico prediction and data-driven approach
Authors: de Jong Jelle C. B. C. , Caspers Martien P. M. , Dulos Remon , Snabel Jessica , van der Hoek Marjanne D. , van der Leij Feike R. , Kleemann Robert , Keijer Jaap , Nieuwenhuizen Arie G. , van den Hoek Anita M. , Verschuren Lars 
Published: December 2024

Abstract Frailty is characterized by loss of physical function and is preferably diagnosed at an early stage (e.g., during pre-frailty). Unfortunately, sensitive tools that can aid early detection are lacking. Blood-based biomarkers, reflecting pathophysiological adaptations before physical symptoms become apparent, could be such tools. We identified candidate biomarkers using a mechanism-based computational approach which integrates a priori defined database-derived clinical biomarkers and skeletal muscle transcriptome data. Identified candidate biomarkers were used as input for a sex-specific correlation analysis, using individual gene expression data from female (n = 24) and male (n = 28) older adults (all 75 + years, ranging from fit to pre-frail) and three frailty-related physical parameters. Male and female groups were matched based on age, BMI, and Fried frailty index. The best correlating candidate biomarkers were evaluated, and selected biomarkers were measured in serum. In females, myostatin and galectin-1 and, in males, cathepsin B and thrombospondin-4 serum levels were significantly different between the physically weakest and fittest participants (all p < 0.05). Logistic regression confirmed the added value of these biomarkers in conjunction with age and BMI to predict whether the subjects belonged to the weaker or fittest group (AUC = 0.80 in females and AUC = 0.83 in males). In conclusion, both in silico and in vivo analyses revealed the sex-specificity of candidate biomarkers, and we identified a selection of potential biomarkers which could be used in a biomarker panel for early detection of frailty. Further investigation is needed to confirm these leads for early detection of frailty.
Resistive force modeling for shallow cone penetration into dry and wet granular layers
Authors: Iikawa Naoki , Katsuragi Hiroaki 
Published: December 2024

AbstractEstimating penetration resistive forces on granular materials is important for applications in various research fields. This paper investigates resistive forces into dry and wet granular layers through theoretical analysis and discrete element simulations. Theoretical model is derived from slip line field theory by assuming materials with cohesion and inter-particle friction. This model indicates that penetration resistive forces are composed of the sum of the buoyancy-like force proportional to the penetration volume and the cohesion-derived force proportional to the penetration cross-sectional area. The model is compared with the simulation results of various cones shallowly penetrating into granular layers with/without liquid-bridge forces between particles. For cohesion-derived force, the simulated resistive forces agree with the theoretical model within a factor of two. For buoyancy-like force, on the other hand, the simulated resistive forces deviate from the theoretical model by up to five times as the cone-tip angle increased. To solve the discrepancy, this paper introduces the correction factor depending on the relationship between stagnant zone and cone shape. As a result, a maximum difference between the proposed model and simulated force are reduced to twice. Thereby, it turns out that the proposed model can compute penetration resistive forces on granular layers in a wide range of cone-tip angles and water content conditions.
Yield and Growth Response of Selected Potato Cultivars to Different Mulch and Fungicide Applications, and Various Localities Under Rainfed Conditions
Authors: Phungula Nosipho Precious Minenhle , Hadebe Sandile Thamsanqa , Schulte-Geldermann Elmar , Sithole Lucky , Ngobese Nomali Ziphorah 
Published: December 2024

AbstractThere is a stark yield gap between sub-Saharan African (SSA) potato productivity compared to other regions, leading to food security challenges. Hence, there is an immediate need to improve SSA potato yield. Research trials were under smallholder settings to determine effective management practices on the integration of selected potato cultivars, fungicides, mulch application, and different localities. Tested factors mulch application (mulch, not mulch), fungicide (sprayed and unsprayed) and different potato cultivars (Electra, Mondial, Panamera, and Sababa) were laid in a randomized complete block design in under five localities (Gobizembe, Hlathikhulu, Mbalenhle, Mbhava, and Stezi), and replicated three times over two consecutive seasons. Data collection included climatic data, emergence, days to flowering, plant height, physiological maturity, stem number yield, and yield components. Integration of Electra, fungicide (sprayed or unsprayed), and mulch application (mulch or not mulch) under humid, low atmospheric water demand, dominated by sandy soils and high-altitude locality had higher yields with the highest of 64.2 t ha−1 and a harvest index of 90.2%. In the locality that is on a south-facing slope, with the lowest altitude, clayed soils had the lowest yield of 13.4 t ha−1 from Mondial cultivar under unsprayed and no mulch. Electra cultivar showed consistent performance under different practices and yielded more across localities. Hence, it is recommended that effective management practices such as Electra together with fungicide (spraying or unsprayed) and mulch (mulch or not mulch) can be adopted to increase potato yield under rainfed conditions.
Commitment ambiguity and ambition in climate pledges
Authors: Tørstad Vegard , Wiborg Vegard 
Published: December 2024

AbstractThe Paris Agreement on climate change is built around a pledge-and-review system, wherein countries submit nationally determined pledges of mitigation commitments. While the agreement’s flexible design has attracted broad participation, its lenient informational requirements for pledges have also engendered considerable ambiguity in countries’ commitments. What are the implications of commitment ambiguity on the credibility of compliance and treaty effectiveness more broadly? This article sheds light on these questions by evaluating the relationship between commitment ambiguity and ambition in countries’ Paris pledges. We introduce a model that disentangles commitment ambiguity into two distinct forms: structural and strategic. We argue that structural ambiguity, which arises from constraints on the information necessary for governments to accurately assess their commitment potential, dampens the ambition levels of pledges. This prudence effect is driven by compliance concern: the anticipation of audience costs in case of non-compliance induces policymakers to adjust ambition downwards. Our empirical analysis of countries’ Nationally Determined Contributions demonstrates that ambiguous pledges exhibit lower ambition than precise ones. In line with our theory, this prudence effect of ambiguity is mainly pronounced among democracies, which face higher domestic audience costs in case of non-compliance with pledges than autocracies. This article contributes a novel theory of ambiguity and ambition in international institutions, which shows how audience-based compliance concerns can discipline cheap talk. Moreover, the article’s empirical findings provide insight into the credibility of countries’ climate pledges under the Paris Agreement, with implications for the treaty’s overall effectiveness prospects.
Quality of life, healthcare usage and finances of UK cancer survivors five years post-diagnosis: a matched controlled study
Authors: Warrington Lorraine , Absolom Kate , Baxter Paul , Bojke Chris , Clarke Gemma , Crossfield Samantha , Johnston Colin , Martin Adam , McInerney Ciaran D. , Saalmink Gwen , Siciliano Michele , Stamp Elizabeth , Velikova Galina , Wilkinson David , Woroncow Barbara , Wright Penny , Zucker Kieran , Hall Geoff , Glaser Adam 
Published: December 2024

Abstract
Purpose
Assessing the long-term impact of cancer on people’s lives is challenging due to confounding issues such as aging and comorbidities. We aimed to investigate this impact by comparing the outcomes of cancer survivors with a matched control cohort.

Methods
This was a cross-sectional survey of breast, colorectal and ovarian cancer survivors approximately 5 years post-diagnosis and a cohort of age, sex and social deprivation-matched controls who had never had a cancer diagnosis. Eligible participants were invited by post to complete a survey assessing quality of life (QoL), health, identity, healthcare usage and finances.

Results
A total of 2075 out of 5734 (36.2%) eligible participants participated (852 cancer survivors and 1223 matched controls). Cancer survivors had poorer QoL than matched controls as assessed by the Quality of Life of Adult Cancer Survivors (QLACS) summary score (p = 0.007); however, the effect size was modest (ω2 = 0.121). The cancer survivors also reported worse outcomes across some individual domains of QoL and health, but not others, and differences were small. There were few differences between cohorts across healthcare usage and finances.

Conclusions
Five years or more after diagnosis, the QoL, healthcare usage and finances of breast, colorectal and ovarian cancer survivors were generally similar to that of age, sex and IMD-matched controls.

Implications for Cancer Survivors
This finding has important implications for people affected by cancer and those providing care who would benefit from greater information on outcomes and functioning beyond treatment. Despite this reassuring finding, it is important to note that there were some differences, on both physical and psychosocial issues, mandating the need for specialist service provision.
Clusterin Deficiency Promotes Cellular Senescence in Human Astrocytes
Authors: Sultana Pinky , Honc Ondrej , Hodny Zdenek , Novotny Jiri 
Published: December 2024

AbstractThe glycoprotein clusterin (CLU) is involved in cell proliferation and DNA damage repair and is highly expressed in tumor cells. Here, we aimed to investigate the effects of CLU dysregulation on two human astrocytic cell lines: CCF-STTG1 astrocytoma cells and SV-40 immortalized normal human astrocytes. We observed that suppression of CLU expression by RNA interference inhibited cell proliferation, triggered the DNA damage response, and resulted in cellular senescence in both cell types tested. To further investigate the underlying mechanism behind these changes, we measured reactive oxygen species, assessed mitochondrial function, and determined selected markers of the senescence-associated secretory phenotype. Our results suggest that CLU deficiency triggers oxidative stress–mediated cellular senescence associated with pronounced alterations in mitochondrial membrane potential, mitochondrial mass, and expression levels of OXPHOS complex I, II, III and IV, indicating mitochondrial dysfunction. This report shows the important role of CLU in cell cycle maintenance in astrocytes. Based on these data, targeting CLU may serve as a potential therapeutic approach valuable for treating gliomas.
Temperature and plastic strain dependent Chaboche model for 316 L used in simulation of cold pilgering
Authors: Azizoğlu Yağız , Lindgren Lars-Erik 
Published: December 2024

AbstractCold pilgering is a complex forming process used to produce seamless tubes, posing significant challenges in material modeling due to its non-proportional loading history and extensive accumulated plastic strain. In this study, a temperature- and plastic strain-dependent Chaboche model for 316 L stainless steel was developed and calibrated. To simulate the complex loading conditions, unique alternating compression-compression tests were conducted, and the model parameters were optimized accordingly. The calibrated model was integrated into a thermo-mechanical finite element simulation of the cold pilgering process, resulting in improved accuracy in predicting stress-strain responses and yield stress evolution. Close agreement with experimental tensile tests of the final tube was demonstrated, illustrating the model’s capability to predict hardening behavior during cold pilgering. Valuable insights and a practical modeling approach for enhancing the simulation and optimization of cold pilgering processes are provided by this work.
Endoscopic ultrasound navigated application of botulinum toxin in severe esophageal motility disorder
Authors: Vážanová Diana , Ďuriček Martin , Uhrík Peter , Bánovčin Peter 
Published: December 2024

Abstract
The use of botulinum toxin in the therapy of esophageal motility disorders is reserved for elderly and comorbid patients considered risky for endoscopic or surgical treatment. However, there is a lack of data on the treatment of motility disorders outside the Chicago classification.
We present the case of a 56-year-old patient with dysphagia and non-cardial chest pain (Eckardt 8). High resolution manometry ruled out achalasia or other motility disorder, but confirmed a localized 7-cm-long spastic segment in the upper to middle third of esophagus. We considered endoscopic or surgical therapy in this location too risky, therefore we decided to apply botulinum toxin into this segment. The spasm on high resolution manometry correlated with the thickened muscularis propria layer according to the endoscopic ultrasound. We used endoscopic ultrasound for the navigation of botulinum toxin application into the muscularis propria layer. We applied 100 IU of botulinum toxin into four quadrants, 20 and 24 cm from front teeth (12.5 IU for 1 application).
The therapy led to improvement of symptoms (Eckardt 3) and to restitution of propulsive peristalsis with complete elimination of spastic segment. The worsening of symptoms appeared after 2 years, with subsequent recurrence of motility disorder fulfilling criteria of type II achalasia.
Presenting this case, we wanted to point at the unique use of botulinum toxin as useful treatment in selected cases of unclassified esophageal motility disorder as a bridge therapy. Moreover, endoscopic ultrasound could be used to guide precise application of botulinum toxin.
Cheilostome bryozoan epibiosis on brachyuran crabs in the Paratethys Sea during the late Badenian (middle Miocene)
Authors: Key Marcus M. , Hyžný Matúš , Zágoršek Kamil , Dulai Alfréd 
Published: December 2024

AbstractThis study quantifies the prevalence of a rarely documented occurrence of bryozoans encrusting fossil brachyuran crabs. Over 500 crab fossils were examined from the reef facies of the Rákos Limestone Member of the Leitha Limestone Formation in the quarry at Diósd, Hungary. They were deposited in the upper part of the regional Badenian stage (i.e., lower part of the international Serravallian stage) of the middle Miocene. Nine bryozoan colonies were found encrusting five dorsal carapaces of three different crab species: Panopeus wronai, Dromia neogenica, and Cancer styriacus. The bryozoans were restricted to the exterior surface of the preserved carapaces of the host crabs, so the epibiosis was most likely syn-vivo. The prevalence was calculated at 1%. The bryozoans were all cheilostome gymnolaemates identified as a cribrilinid, a calloporid, Onychocella? sp., and two indeterminate membraniporiform species. The low prevalence of bryozoan-encrusted crabs is consistent with other fossil-based bryozoan-crab studies but much lower than similar studies in today’s faunas. This discrepancy was attributed to both colony spalling-induced preservational bias and differences in carapace size. The bryozoan-crab symbiosis was described as phoretic hitchhiking.
Effectiveness of Decentralization of Disaster Risk Management in Borana and South-West Shawa Zones, Oromia Region, Ethiopia
Authors: Tolessa Terefe , Fana Chalchisa , Gadissa Deressa , Takela Ermiayas , Tesso Gutu 
Published: December 2024

AbstractThis study was designed with the aim of assessing the effectiveness of decentralization of disaster risk management in Borana zone and South-West Shawa zone of Oromia region. A mixed research approach was used to collect data from federal, regional, zonal, district (woreda), and ward (kebele) representatives. Focus group discussions and key informant interviews were the qualitative methods used to collect data, while survey questionnaires were distributed to experts to collect quantitative data. The qualitative data were analyzed using content analysis whereas the quantitative data were analyzed using STATA software version 14. The findings of the research have shown that, the actors are aware of Busa Gonofa as a new indigenous self-help institution. The policy on decentralization of disaster risk reduction was better understood at the federal, regional, and zonal levels of the government tiers than at the woreda and kebele levels. Administrative decentralization was found to be more effective than fiscal and political decentralization. The decentralization of Ethiopian disaster risk reduction is incomplete with limited effectiveness. There exists significant difference between Borana and South-West Shawa zones in decentralization of disaster risk management. The implementation of decentralization was constrained by training, technology, collaboration, financial resources, skill and knowledge, institutional arrangement, and local capacity. Hence, there is a need to address these challenges and make continuous efforts to focus on local-level capacity building in terms of empowerment of actors through training, technology, and financial resources for adaptation and mitigation to drought in Borana and flood in South-West Shawa zones respectively.