bluuebunny/crossref_metadata_2025_split huggingface dataset:
What Determines the Type and Dose of Antibiotic That Is Needed to Be Added to the Cement Spacer in Patients With Infected Total Ankle Arthroplasty (TAA)?
Authors: Shakked Rachel , Da Rin de Lorenzo Ferdinando 
Published: July 2019

Recommendation: We recommend tailoring the antibiotic in cement spacers to the infecting organism if it has been identified, as is typically done in total knee and hip arthroplasty. Otherwise, broad-spectrum antibiotics may be utilized. Medical comorbidities should always be considered, especially with regard to renal function and allergy profile. A thermostable antibiotic should be added to cement. Level of Evidence: Consensus. Delegate Vote: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus).
How Should Postoperative Cellulitis Be Treated in Patients With Total Ankle Arthroplasty (TAA) in Place?
Authors: Plöger Milena M. , Murawski Christopher D. 
Published: July 2019

Recommendation: In the absence of evidence, we recommend that (1) patients with total ankle arthroplasty (TAA) in place who develop postoperative cellulitis be evaluated thoroughly to rule out periprosthetic joint infection of the ankle, and that (2) isolated cellulitis may be treated with antibiotics, elevation, and close monitoring. Aspiration can be considered in certain cases, with the potential risk of introducing deep space infection. Level of Evidence: Consensus. Delegate Vote: Agree: 92%, Disagree: 0%, Abstain: 8% (Super Majority, Strong Consensus).
Postoperative Opioid Consumption in Opioid-Naïve Patients Undergoing Hallux Valgus Correction
Authors: Rogero Ryan , Fuchs Daniel , Nicholson Kristen , Shakked Rachel J. , Winters Brian S. , Pedowitz David I. , Raikin Steven M. , Daniel Joseph N. 
Published: July 2019

Background: Postoperative pain management following orthopedic surgeries can be challenging, and the opioid epidemic has made it essential to better individualize opioid prescriptions by patient and procedure. The purpose of this subgroup analysis of a prospective study was to investigate immediate postoperative opioid pill consumption and prolonged use in patients undergoing operative correction of hallux valgus (HV). Methods: Patients undergoing outpatient HV correction procedures with 5 fellowship-trained foot and ankle surgeons over a 1-year period were included. Patients were excluded if they were being prescribed chronic opioid analgesics for an underlying condition prior to the date of initial injury or if they underwent concomitant nonforefoot procedures. At the patient’s first postoperative visit, opioid pills were counted, and these were standardized to the equivalent number of 5-mg oxycodone pills. Linear regression analysis was performed to determine if any of the procedure categories or patient factors were independently associated with postoperative opioid consumption. Prolonged use of opioids 90 to 180 days after the procedure was also examined using our state’s online Prescription Drug Monitoring Program (PDMP). One-hundred thirty-seven patients (86% female) were included. Thirty-six patients (26%) underwent primary chevron osteotomies, 78 (57%) underwent primary proximal osteotomies (Ludloff, scarf), 10 (7%) underwent soft tissue–only procedures with or without a first proximal phalanx osteotomy (modified McBride, Akin), and 13 (9%) underwent first metatarsophalangeal arthrodeses. Results: Overall, patients consumed a median of 27 pills. There was no significant difference in postoperative opioid intake between the 4 procedures, including when subdivided into those with and without lesser toe procedures. Higher preoperative visual analog scale pain levels ( P = .028) and younger patient age ( P = .042) were associated with higher opioid pill consumption. A total of 1.5% of patients demonstrated prolonged opioid use. Conclusion: Our study demonstrated a lack of difference between HV procedures in terms of postoperative opioid consumption and an overall low rate of prolonged use in opioid-naïve patients. Level of Evidence: Level III, comparative study.
Effects of timing parameter changes on the gait of functional electrical stimulation users with drop foot
Authors: Marchant Simon , Michael Shona , Milner Laura , Tang Kit-Tzu 
Published: July 2019

Introduction Functional electrical stimulation uses clinician-set parameters to modify stimulation. This study aimed to investigate whether timing parameters in the ODFS Pace functional electrical stimulation device have an effect on the gait of the general population of functional electrical stimulation users who have a foot drop. Methods Twelve functional electrical stimulation users with foot drop resulting from upper motor neurone disorders were recruited from the functional electrical stimulation Service in Leeds, UK. A crossover trial design was used, comparing adjusted values of rising ramp, delay and extension. Instrumented gait analysis was carried out to measure ankle dorsiflexion during the swing phase of gait, foot clearance from the ground, and speed of ankle plantarflexion at initial contact. The effect of timing parameters on gait kinematics was studied. Results No statistically significant effects on the measured parts of gait were found for any of the timing parameters. Trends were identified in average mid-swing ground clearance and dorsiflexion associated with the delay and rising ramp timing parameters. Conclusions Further work in this area should use larger numbers of participants. Based on these results, the effects of ramping and delay would be of particular interest for further study.
Tisagenlecleucel CAR T-cell therapy in secondary CNS lymphoma
Authors: Frigault Matthew J. , Dietrich Jorg , Martinez-Lage Maria , Leick Mark , Choi Bryan D. , DeFilipp Zachariah , Chen Yi-Bin , Abramson Jeremy , Crombie Jennifer , Armand Philippe , Nayak Lakshmi , Panzini Chris , Riley Lauren S. , Gallagher Kathleen , Maus Marcela V. 
Published: July 2019

AbstractChimeric antigen receptor (CAR) T cells targeting CD19 have emerged as a leading engineered T-cell therapy for relapsed/refractory B-cell non-Hodgkin lymphoma. The phase 1/2 clinical trials that led to US Food and Drug Administration approval excluded patients with central nervous system (CNS) involvement, due to strict eligibility criteria. Here, we report on our institutional experience with 8 secondary CNS lymphoma patients treated with commercial tisagenlecleucel. No patient experienced greater than grade 1 neurotoxicity, and no patient required tocilizumab or steroids for CAR T-cell–mediated toxicities. Biomarker analysis suggested CAR T-cell expansion, despite the absence of systemic disease, and early response assessments demonstrated activity of IV infused CAR T cells within the CNS space.
Evaluation of temporomandibular joint, masticatory muscle, and brain cortex activity in patients treated by removable functional appliances: a prospective fMRI study
Authors: Ozdiler Orhan , Orhan Kaan , Cesur Emre , Köklü Ayşegül , Algın Oktay 
Published: July 2019

Objectives: The aim of this study is to evaluate the effects of functional orthodontic appliances on the masticatory muscles, temporomandibular joint (TMJ), and brain to determine whether using functional appliances full-time or only at night yields different results. Methods: 16 patients with Class II malocclusion were included in this study. Eight patients were instructed to wear their appliances (monoblock/twinblock) full-time and the other eight patients were instructed to wear them at night while sleeping. An additional 10 patients with Class II malocclusion were later included as a pre-treatment control group. Signal intensity ratios (SIR) of TMJ structures and morphological evaluations of the masticatory muscles were done for all patients. Functional MRI (fMRI) data were also obtained from the patients while performing chewing and biting movements. Results: ANB angle was reduced significantly in both the full-time and night wear groups, by values of 1.17° and 1.35°, respectively (p < 0.05). MRI showed that SIRs were significantly increased in both groups in the masticatory muscles, retrodiscal pad, condylar process, and articular disc (p < 0.05). Both resting and task-based fMRI evaluation revealed significant increases in blood oxygen level dependent signals in several regions of the brain in both groups (p < 0.05). Conclusions: The cephalometric and MRI findings of this study indicate that the treatment effects were similar for both wear schedules. Functional appliances should be regarded not as simple devices that treat Class II malocclusion through skeletal and dental correction alone, but as exercise devices that lead to neuromuscular changes by facilitating muscle adaptation and activating various brain regions.
Entrepreneurial Uncertainty and Expert Evaluation: An Empirical Analysis
Authors: Scott Erin L. , Shu Pian , Lubynsky Roman M. 
Published: July 2019

This paper empirically examines the evaluations of 537 ventures in high-growth industries performed by 251 experienced entrepreneurs, investors, and executives. These experts evaluated ventures by reading succinct summaries of the ventures without meeting the founding teams, and their evaluations were not disclosed to the entrepreneurs. We find that experts can differentiate among early-stage ventures on grounds of quality beyond the explicit venture and entrepreneur characteristics contained in the written summaries. They can only do so effectively, however, for ventures in the hardware, energy, life sciences, and medical devices sectors; they cannot do so for ventures in the consumer products, consumer web and mobile, and enterprise software sectors. Our results highlight sector-specific heterogeneity in the information needed to effectively screen ventures, a finding that has implications for the design of optimal investment strategies. This paper was accepted by Gustavo Manso, finance.
تعليم مخارج الحروف العربية وأثاره فى مهارة القراءة
Authors: Fitria Aida 
Published: July 2019

أما المشكلة في هذا البحث فهي كيف كان تعليم مخارج الحروف العربية وأثاره في مهارة القراءة فى المدرسة الثانوية الحكومية بادنج غانتينج. إن أغراض البحث من هذه الرسالة فهي معرفة نتيجة تعليم اللغة العربية في المدرسة الثانوية الحكومية بادنج غانتينج فى الفصل الضبطى، و معرفة نتيجة فى الفصل التجريبي على مهارة القراءة بدون تعليم مخارج الحروف العربية وبتعليمها فى هذه المدرسة، ولمعرفة تأثير تعليم أصوات العربية الصعبة فى مهارة القراءة فى هذه المدرسة أقامت الباحثة إجراءات تعليم الأصوات العربية. أما المنهج في البحث عن هذه الرسالة فهو البحث الميداني الكمي في النوع التجريبي، والطريقة المستعملة هي طريقة إحصائية. النتيجة التي حصلتها الباحثة فهي أما النتيجة التى حصلتها الكاتبة في الفصل التجريبي أن تعليم مخارج الحروف العربية له أثار فى مهارة القراءة. ونتيجته بالرمز t يعني 8,358، و في الفصل الضبطى ليست هناك تأثير تعليم مخارج الحروف العربية فى مهارة القراءة فى المدرسة الثانوية الحكومية بادنج غانتينج . والنتيجة التى حصلتها الكاتبة في الفصل الضبطى والفصل التجريبي با لرمز t يعني 2,42 ، فى الدرجة 5% فرض العدمية مردودة والفرض المباشر مقبولة، المراد بها أن هناك وجدت الكاتبة تأثير تعليم مخارج الحروف العربية في مهارة القراءة في هذه المدرسة، والعكس فى الدرجة 1% فرض العدمية مردودة والفرض المباشر مقبولة، المراد بها أن هناك ما وجدت الكاتبة تأثير إجابية تعليم مخارج الحروف العربية في مهارة القراءة في هذه المدرسة. وتعليم مخارج الحروف العربية لها أثار فى مهارة القراءة ، فلا يمكن أن تكون القراءة الصحيحة بدون مراعات الحروف من ناحية صفاتها ومخارجها.
Analisis Kesalahan Sintaksis Pada Buku Teks Duru>Su Al-Lughah Al-Ara>Biyah ‘Ala> Thoriqotial-Muba>Syarah Al-Muta>Kamilah Karya Muhammad In’am, M.A
Authors: Hidayah Ihdatul , Asyrofi Syamsuddin 
Published: July 2019

This study aims to find out about language errors that occur in an Arabic textbooks entitled Duru>s al-Lughah al-‘Ara>biyah ‘ala Thariqati al-Muba>syarah al-Mutaka>milah of Muhammad In'am, M.A. Not only the errors that were discussed but there was an attempt or Tashwib or correction in order to evaluate the results of the analysis that has been done. Library research was used with a qualitative descriptive method to analyze the subject of the study which is Duru>s al-Lughah al-‘Ara>biyah ‘ala Thariqati al-Muba>syarah al-Mutaka>milah both volumes I and II. In this study, the following conclusions can be drawn: there are errors in language syntactic aspects in the textbooks. There are several categories of errors (refer to the classification of Toto Suharto et al): nakirah Ma'rifah, Dhamir, huruf Jar, Murakkab Idhafi, Isim Isyarah, Jumlah Ismiyah, and Jumlah Fi'liyah. Several reasons were found for the occurrence of these errors, namely lack of accuracy in writing textbooks, lack of workforce that helped the author to edit the material to be presented in textbooks and limited human resources which led to inefficient writing of textbooks.
Abstrak
Penelitian ini bertujuan untuk mengetahui tentang beberapa kesalahan-kesalahan berbahasa yang terjadi dalam penulisan buku teks bahasa Arab Duru>s al-Lughah al-‘Ara>biyah ‘ala Thariqati al-Muba>syarah al-Mutaka>milah karya Muhammad In’am. MA, bukan hanya kesalahan-kesalahan yang dibahas tapi ada upaya Tashwib atau pembenaran guna sebagai evaluasi dari hasil analisis yang telah dilakukan. Ketegori yang digunakan penelitian library research dengan metode deskriptif kualitatif. Dengan objek buku teks bahasa Arab Arab Duru>s al-Lughah al-‘Ara>biyah ‘ala Thariqati al-Muba>syarah al-Mutaka>milah karya Muhammad In’am. MA baik jilid I dan II. Dalam penelitian ini dapat diambil kesimpulan sebagai berikut, bahwa: adanya kesalahan-kesalahan berbahasa aspek sintaksis dalam buku teks Duru>s al-Lughah al-‘Ara>biyah ‘ala Thariqati al-Muba>syarah al-Mutaka>milah karya Muhammad In’am. MA baik jilid I dan II. Ditemukan beberapa kategori kesalahan (merujuk pada klasifikasi Toto Suharto dkk): Nakirah Ma’rifah, Dhamir, huruf Jar, Murakkab Idhafi, Isim Isyarah, Jumlah Ismiyah, dan Jumlah Fi’liyah. di temukan beberapa alasan terjadinya kesalahan-kesalahan tersebut yakni kurangnya ketelitian dalam menulis buku teks, kurangnya tenaga kerja yang membantu penulis dalam mengedit materi-materi yang akan di sajikan dalam buku teks, keterbatasan sumber daya manusia yang menyebabkan kurang efisien dalam menulis buku teks.
Kata kunci: Buku Teks, Analisis kesalahan, Sintaksis, Duru>s al-Lughah al-‘Ara>biyah ‘ala Thariqati al-Muba>syarah al-Mutaka>milah.
Akar Historis Lahirnya Ilmu Nahwu
Authors: Hairuddin  
Published: July 2019

This journal discusses Nahwu's Usul which covers Qiyas, Illat, and Ta'wil using the Library Study method with a Descriptive Historical Qualitative approach. As for the main sources in writing this Journal are the books that contain the discussion of Qiyas, Illat, and Tawil and their relation to Greek Philosophy. The author concludes that Nahwu Science was born due to errors in reading the Koran because of the occurrence of birth among speakers of Arabic, not because of the influence of Greek Philosophy, but it cannot be denied that certain themes are influenced by other Sciences, such as methods the formation of Arabic rules inspired by the Science of Jurisprudence, and Ta'lil inspired by the way of thinking of the Greek Philosophers, but in general the application of the Nahwu Science had existed before the interaction between Muslim Scientists and Philosophers.
Abstrak
Jurnal ini membahas Ushul Nahwu yang mencakup Qiyas, Illat, dan Ta’wil dengan menggunakan metode Kajian Pustaka dengan pendekatan Kualitatif Historis Deskriftif. Adapun yang menjadi sumber utama dalam penulisan Jurnal ini adalah kitab-kitab yang memuat pembahasan Qiyas, Illat, dan Ta’wil dan keterkaitannya dengan pemikiran Filsafat Yunani. Penulis berkesimpulan bahwa Ilmu Nahwu lahir akibat adanya kesalahan dalam membaca al-Qur’an karena terjadinya lahn dikalangan penutur bahasa Arab, bukan karena pengaruh Filsafat Yunani, hanya saja tidak bisa dipungkiri bahwa ada tema-tema tertentu dipengaruhi oleh Ilmu-ilmu lain, seperti metode pembentukan kaidah-kaidah bahasa Arab terinspirasi dari Ilmu Fikih, dan Ta’lil terinspirasi dari cara berpikirnya para Filosof Yunani, tetapi secara umum penerapan Ilmu Nahwu sudah ada sebelum adanya interaksi antara Ilmuwan Muslim dan para Filosof.
Kata Kunci: Nahwu, Filsafat, Qiyas
UU Pesantren: Local Genius dan Intervensi Negara terhadap Pesantren
Authors: Setyawan Maulana Arif 
Published: July 2019

Abstract
There is no doubt that pesantrens have a real contribution to the development of education. Historically, they have extensive experiences in fostering and developing the community. In fact, pesantrens are able to increase their role independently by exploring the potential of the communities around them. Improving the role of pesantren is a strategic step in building national development goals, especially in the education sector. For this reason, to develop their potential, the government drafted pesantren and religious law. On the contrary, the draft of law raises anxiety among pesantrens because it is perceived to disturb their management. In addition, it may become the tool for government intervention in Islamic boarding school system, which in turn may loose their distinctive characteristics as a local genius education institution in Indonesia. This research is an analytical study with a qualitative approach. The study found that the Islamic Boarding School and Religious Education Law aims to form individuals who understand and practice the values ​​of their religion or become religious scholars who are faithful, pious, noble, knowledgeable, independent, ta'awun, tawazun and tawasut. The Islamic boarding school law has the advantage of being able to serve a clearer direction for the boarding school. However, its’ shortcomings are it open wider possibility of government interventions that may interfere household matters of the pesantrens too deeply, even though the pesantren is indeed an independent institution.
Production of uronic acids by hydrothermolysis of pectin as a model substance for plant biomass waste
Authors: Pińkowska Hanna , Krzywonos Małgorzata , Wolak Paweł , Złocińska Adrianna 
Published: July 2019

Abstract
The hydrolysis of high methyl ester citrus-apple pectin as a model substance for plant biomass waste rich in pectin fraction resulting in an uronic acids was performed in a batch reactor using subcritical water. The effects of the reaction temperature and time on the composition of the products contained in the separated liquid fractions were studied. The optimal experimental design methodology was used for modelling and optimizing the yield of uronic acids. In good agreement with experimental results (R2 = 0.986), the model predicts an optimal yield of uronic acids (approx. 77.3 g kg-1 ± 0.7 g kg-1) at a temperature and a time of about 155°C and 36 min. Uronic acids were isolated from reaction mixture using the ion exchange method. Higher temperature and longer holding time resulted in a greater degree of thermal degradation of uronic acids and simultaneously higher yield of losses and gas fractions
Pregnancy outcomes after thyroid cancer
Authors: Spiegel Efrat , Spence Andrea R. , Czuzoj-Shulman Nicholas , Abenhaim Haim Arie 
Published: July 2019

Abstract

Background
Thyroid cancer is one of the most common cancers in women of reproductive age. Our purpose was to evaluate the association between thyroid cancer and maternal and neonatal outcomes of pregnancy.

Methods
We conducted a retrospective cohort study using the Healthcare Cost and Utilization Project, Nationwide Inpatient Sample (HCUP-NIS) database from the US. A cohort consisting of women who delivered between 1999 and 2014 was created. Multivariate logistic regression, controlling for baseline maternal characteristics, was used to compare pregnancy complications and neonatal outcomes of pregnant women with thyroid cancer [International Classification of Diseases, ninth edition (ICD-9) code 193] diagnosed before or during pregnancy with those of the obstetric population without thyroid cancer.

Results
The study included 14,513,587 pregnant women, of which 581 women had a diagnosis of thyroid cancer (4/100,000). During the observation period, there was an upward trend in the prevalence of thyroid cancer among pregnant women, though not statistically significant (P = 0.147). Women with thyroid cancer were more likely to be Caucasian, belong to a higher income quartile, have private insurance, to be discharged from an urban teaching hospital and to have pre-gestational hypertension. Women with thyroid cancer had a greater chance of delivering vaginally, requiring transfusion of blood and developing venous thromboembolism (VTE). Neonates of mothers with thyroid cancer were not found to be at increased risk for the adverse neonatal outcomes examined, specifically, congenital malformations, intrauterine growth restriction, fetal death and preterm labor.

Conclusion
Pregnancies complicated by thyroid cancer have higher incidences of VTE and need for transfusions, with comparable overall newborn outcomes.
Transition metals doped ZnO nanocluster for ethylene oxide detection: A DFT study
Authors: Afshari Tooba , Mohsennia Mohsen 
Published: July 2019

Abstract
Density functional theory (DFT) studies at B3LYP/6-31G (d) (Becke, 3-parameter, Lee-Yang-Parr) level were performed to evaluate adsorption interactions between ethylene oxide (EO) molecule, and pristine and transition metals (TM) (i.e., Sc, Ti, V, Cr, Mn, Fe, Co, Ni, and Cu) doped ZnO nanocluster (TM-doped Zn12O12). The adsorption energy (Ead), band gap energy (Eg), Mulliken charge transfer (QT) and molecular electrostatic potential (MEP) were calculated to examine the sensitivity of the Zn12O12 and its TM-doped forms toward EO detection. It was found that in contrast to the pristine Zn12O12, the electronic properties of TM-doped Zn12O12 were sharply sensitive to the presence of EO gas molecules. The results revealed that among the studied TM-doped Zn12O12, Cr- and V-doped Zn12O12 have great potential applicability as EO sensor, due to their highest Eg change (ΔEg) values, after the EO adsorption. Moreover, the density of state (DOS) calculations confirmed that strong electronic interaction between Cr- and V-doped Zn12O12 and EO molecules can makes them interesting empirical candidate for detection and adsorptive removal of EO gas molecules.
The crystal structure of (4Z)-2-[(E)-(1-ethyl-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene)methyl]-4-[(1-ethyl-3,3-dimethyl-3H-indolium-2-yl)methylidene]-3-oxocyclobut-1-en-1-olate, C30H32N2O2
Authors: Asiri Abdullah M. , Arshad Muhammad Nadeem , Albukhari Soha M. , Al-Soliemy Amerah M. 
Published: July 2019

Abstract
C30H32N2O2, monoclinic, P21/c (no. 14), a = 9.8611(2) Å, b = 15.8027(3) Å, c = 16.2473(3) Å, β = 100.150(2)°, V = 2492.23(8) Å3, Z = 4, R
gt(F) = 0.0542, wR
ref(F
2) = 0.1677, T = 296(3) K.
Optimization of the microstructure of carbonized lime mud by sodium polyacrylate
Authors: Wang Jian , Xu Yaowei , Wang Zhijie , Sun Jianpeng , Liu Min 
Published: July 2019

Abstract
Lime mud (LM) is a by-product originated from the causticization process of papermaking industry. Microscopic structural changes of LM in carbonization process lead to defects on its performance. Regulating the growth of calcium carbonate obtained from the carbonization process and preventing its influence on the surface microstructure of LM has become the key to achieve the self-digestion of this solid waste. In this study, microscopic structural changes of LM co-carbonized with sodium polyacrylate (PAAS) were investigated. The results showed that, compared with traditional carbonation, the microstructure of LM co-carbonized with PAAS was changed remarkably. The newly calcium carbonate formed in the carbonization process would be solidified and coated on the LM surface. Then LM co-carbonized with PAAS would have a smaller specific surface area, pore volume and pore size, which significantly improved its application performance when it was used as paper filler. In addition, a potential technique for improving the surface microstructure of calcium carbonate particle was proposed.