bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Endoscopic Endonasal Management of Anterior Skull Base Meningiomas
Authors: Guaraldi Federica , Pasquini Ernesto , Frank Giorgio , Mazzatenta Diego , Zoli Matteo 
Published: August 2018

Introduction The endoscopic endonasal approach (EEA) might seem an “unnatural” route for intradural lesions such as meningiomas. The aim of this study is to critically revise our management of anterior skull base meningiomas to consider, in what cases it may be advantageous.
Material and Methods Each consecutive case of anterior skull base meningioma operated on through an EEA or combined endoscopic–transcranial approach at our institution, between 2003 and 2017, have been included. Tumors were classified on the basis of their location and intra or extracranial extension. Follow-up consisted of an MRI (magnetic resonance imaging) and a clinical examination 3 months after the surgery and then repeated annually.
Results Fifty-seven patients were included. The most common location was the tuberculum sellae (62%), followed by olfactory groove (14%), planum sphenoidale (12%), and frontal sinus (12%). Among these, 65% were intracranial, 7% were extracranial, and 28% both intra and extracranial. Radical removal was achieved in 44 cases (77%). Complications consisted in 10 CSF (cerebrospinal fluid) leaks (17.6%), 1 overpacking (1.7%), and 1 asymptomatic brain ischemia (1.7%). Visual acuity and campimetric deficits improved respectively in 67 and 76% of patients. Recurrence rate was of 14%.
Conclusions EEA presents many advantages in selected cases of anterior skull base meningioma. However, it is hampered by the relevant risk of CSF leak. We consider that it could be advantageous for planum/tuberculum sellae tumors. Conversely, for olfactory groove or frontal sinus meningiomas, it can be indicated for tumors with extracranial extension, while its role is still debatable for purely intracranial forms as considering our surgical results, it could be advantageous for midline planum/tuberculum sellae tumors. Conversely, it can be of first choice for olfactory groove or frontal sinus meningiomas with extracranial extension, while its role for purely intracranial forms is still debatable.
Telomere shortening is a hallmark of genetic cardiomyopathies
Authors: Chang Alex C. Y. , Chang Andrew C. H. , Kirillova Anna , Sasagawa Koki , Su Willis , Weber Gerhard , Lin Jue , Termglinchan Vittavat , Karakikes Ioannis , Seeger Timon , Dainis Alexandra M. , Hinson John T. , Seidman Jonathan , Seidman Christine E. , Day John W. , Ashley Euan , Wu Joseph C. , Blau Helen M. 
Published: August 2018

Significance
We find that telomere shortening, which usually accompanies cell division in the course of aging, occurs in cardiomyocytes (CMs) of individuals with genetic hypertrophic cardiomyopathy (HCM) or dilated cardiomyopathy (DCM). HCM and DCM CMs differentiated from human-induced pluripotent stem cells (hiPSCs) also exhibit significant telomere shortening relative to healthy controls. By contrast, no telomere shortening was detected in vascular smooth muscle cells in tissue or hiPSC-derived cells, a cell type that does not express the mutant proteins. Our findings provide evidence for accelerated aging in CMs with familial cardiomyopathy. The potential to monitor the dynamics of telomere attrition in hiPSC-CMs over time will enable future mechanistic studies and screens for novel therapeutic agents to arrest telomere shortening and disease progression.
Responses to pup vocalizations in subordinate naked mole-rats are induced by estradiol ingested through coprophagy of queen’s feces
Authors: Watarai Akiyuki , Arai Natsuki , Miyawaki Shingo , Okano Hideyuki , Miura Kyoko , Mogi Kazutaka , Kikusui Takefumi 
Published: August 2018

Significance
In a colony of naked mole-rats, instead of a single breeding female (the queen) nursing alone, sexually immature members (subordinates) show positive alloparental pup care. Their response to pup vocalizations is not continuous, but rather is enhanced during the queen’s postpartum period through consumption of the pregnant queen’s feces. Furthermore, oral ingestion of the pregnant queen’s feces also induces an increase in the subordinates’ estradiol concentrations. Because subordinates’ responses to pup vocalizations were enhanced through the ingestion of nonpregnant queen’s feces amended with estradiol, we concluded that estradiol is the substance that enhances their responses to pup vocalizations in naked mole-rats. Moreover, these results suggest that naked mole-rats communicate the substance between the queen and subordinates through coprophagy.
Default mode network can support the level of detail in experience during active task states
Authors: Sormaz Mladen , Murphy Charlotte , Wang Hao-ting , Hymers Mark , Karapanagiotidis Theodoros , Poerio Giulia , Margulies Daniel S. , Jefferies Elizabeth , Smallwood Jonathan 
Published: August 2018

Significance
Accounts of the default mode network (DMN) as task negative are partly based on evidence for a role of this system in off-task thought. We revisited the evidence for this assumption in a study combining experience sampling with functional neuroimaging. Whether thoughts were related or unrelated to an ongoing task was associated with patterns of neural activity in regions adjacent to unimodal sensorimotor cortex. In contrast, during periods of working-memory maintenance, activity patterns in the DMN were associated with whether thoughts were detailed. These results demonstrate that activity within the DMN encodes information associated with ongoing cognition that goes beyond whether attention is directed to the task, including detailed experiences during active task states.
Size and topology modulate the effects of frustration in protein folding
Authors: Kluber Alex , Burt Timothy A. , Clementi Cecilia 
Published: August 2018

Significance
Frustration is a central concept in the study of protein folding kinetics. While it has been proposed that most proteins are minimally frustrated, recent experiments have found systems with surprisingly slow reconfiguration dynamics, suggesting an underlying landscape that is frustrated or “rough.” Our results suggest that protein size and topology play a role in determining how sensitive a protein is to frustration.
Determinants of refugee naturalization in the United States
Authors: Mossaad Nadwa , Ferwerda Jeremy , Lawrence Duncan , Weinstein Jeremy M. , Hainmueller Jens 
Published: August 2018

SignificanceDespite the scale of the US refugee resettlement program, policymakers and the public lack systematic information on how refugees adapt to their new environment. We focus on naturalization as a key measure of integration and draw on administrative data to provide direct estimates of the naturalization rates among refugees. Our results show that, on average, refugees acquire citizenship faster than other lawful permanent residents. We also identify the set of factors that promote or constrain naturalization among refugees. These findings have implications for policymakers seeking to improve the integration of refugees within the United States.
Absorption by water increases fluorescence image contrast of biological tissue in the shortwave infrared
Authors: Carr Jessica A. , Aellen Marianne , Franke Daniel , So Peter T. C. , Bruns Oliver T. , Bawendi Moungi G. 
Published: August 2018

Significance
Shortwave infrared (SWIR) fluorescence imaging is a tool for visualizing biological processes deep within tissue or living animals. Our study shows that the contrast in a SWIR fluorescence image is primarily mediated by the absorptivity of the tissue, and can therefore be tuned through deliberate selection of imaging wavelength. We show, for example, that, in 3D tissue phantoms and in brain vasculature in vivo in mice, imaging at SWIR wavelengths of the highest water absorptivity results in the greatest fluorescence contrast. We further demonstrate, in microscopy of ex vivo mouse liver tissue, that imaging at wavelengths of high tissue absorptivity can also increase imaging penetration depth, and use a theoretical contrast model to explain this effect.
Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation
Authors: Kono Michihito , Yoshida Nobuya , Maeda Kayaho , Skinner Nicole E. , Pan Wenliang , Kyttaris Vasileios C. , Tsokos Maria G. , Tsokos George C. 
Published: August 2018

Significance
Th17 cells favor glycolytic metabolism. Pyruvate dehydrogenase, which facilitates entry into the oxidative phosphorylation circle, is inhibited by pyruvate dehydrogenase phosphatase catalytic subunit 2 (PDP2). Our studies demonstrate that the transcription factor ICER/CREM, which is known to promote Th17 differentiation and related pathology, suppresses the expression of PDP2 and diverts energy production into the glycolytic pathway. In lupus-prone mice and people with systemic lupus erythematosus, PDP2 levels are decreased and its replenishment suppresses Th17 differentiation.
Asymptotic theory of rerandomization in treatment–control experiments
Authors: Li Xinran , Ding Peng , Rubin Donald B. 
Published: August 2018

Significance
Rerandomization refers to experimental designs that enforce covariate balance. This paper studies the asymptotic properties of the difference-in-means estimator under rerandomization, based on the randomness of the treatment assignment without imposing any parametric modeling assumptions on the covariates or outcome. The non-Gaussian asymptotic distribution allows for constructing large-sample confidence intervals for the average treatment effect and demonstrates the advantages of rerandomization over complete randomization.
Uso de corpus monolingües comparables para la traducción al francés de unidades de núcleo verbal procedentes de la
sección económico-financiera del diario El País
Authors: Le Poder Marie-Évelyne 
Published: August 2018

Abstract
This work is based on the development of two comparable monolingual corpus works in Spanish and French, made up of articles from
the electronic versions of two daily newspapers, El País and Le Monde (from January 1, 2007 to December 31, 2011).
First, based on articles published in economic and financial section of El País, we identify terminological and phraseological
units which include the word “crisis,” which we take as the verbal core of the main lexical structure of the corpus in
Spanish.
Second, we focus on the articles in the corpus in French, finding equivalents for these units. The study reveals three possible
situations: Le Monde provides clear equivalents in context; it proposes unclear equivalent words in context; or it doesn’t provide
any equivalents, which means translators must start from scratch.
The main research interest is the range of proposed translations that are presented around a ubiquitous term in today’s press,
which might be useful for both translators and translation students.
Also noteworthy: the use of a monolingual corpus composed of original texts for finding translation equivalents, as opposed to
translated texts more frequently found in traditional translation-oriented analysis.
The econo-linguistics approach to the study of investor sentiment
Authors: Chan Clara Ho-yan , Sin King-kui , T’sou Benjamin Ka Yin 
Published: August 2018

Abstract
This paper sets out to examine the existing literature in the study of investor sentiment, and propose research areas in the
Pan-Chinese context by use of the econo-linguistics approach. This new research may provide insights into the mindset of Chinese
investors by explicating the language that represents it. Such language arises in public financial discourse that involves the use
of special terminology and metaphorical expressions in Hong Kong, Mainland China and Taiwan and may contribute to influencing
investment behaviour and outcome. Following the review of the research, this paper proposes the use of an innovative mechanism and
platform for systemizing financial terminologies and facilitating financial research within the inter-disciplinary framework of
econo-linguistics, especially in the Pan-Chinese regions.
Measuring emotional temperatures in Shakespeare’s drama
Authors: Culpeper Jonathan , Findlay Alison , Cortese Beth , Thelwall Mike 
Published: August 2018

Abstract
This paper demonstrates how the computational analysis of Shakespeare’s plays can map the emotional language used across individual
plays and across the canon more broadly, affording new insights. It explains how we adapted the “sentiment analysis” tool
SentiStrength for use with Early Modern English. Our analyses allow us to test out the long-held critical
hypothesis that Shakespeare’s work moved from a comic to a “problem” and tragic period, and thence to a more optimistic redemptive
mood in his last plays. The paper will also suggest how computational techniques can further understanding of genre, in particular
the relationship between history and tragedy in Shakespeare’s work.
Can native-speaker corpora help explain L2 acquisition of tense and aspect?
Authors: Tracy-Ventura Nicole , Cuesta Medina Jhon A. 
Published: August 2018

Abstract
This study investigates the distributional patterns of verb form frequencies in the Spanish past tense (the Preterit and the Imperfect) in the Corpus del Español (Davies, 2002). Following a usage-based approach, we examine the potential influence of input frequency as a driving factor in L2 learning. Results provide support for the existence of a distributional bias in L1 Spanish, with several telic predicates more often occurring in the Preterit and several atelic predicates in the Imperfect. Results also demonstrate that the distribution of verbs in the Preterit and the Imperfect is Zipfian, with the most frequent verbs overall accounting for the majority of all the tokens. Finally, an analysis of the different meanings of the Imperfect demonstrates clear differences in frequency of use with the continuous meaning as the most frequently expressed meaning, followed by habituality and progressivity. Implications for research and teaching are discussed.
Arabic learners’ acquisition of English past tense morphology
Authors: Zhao Helen , Shirai Yasuhiro 
Published: August 2018

Abstract
The current study investigates the roles of lexical aspect and phonological saliency in second language acquisition of English past tense morphology. It also explores whether the effects of these factors are affected by data elicitation tasks and learners’ L2 proficiency. We created a learner corpus consisting of data from oral personal narratives from twenty Arabic EFL learners from two proficiency groups (low vs. intermediate/advanced), which were transcribed in CHAT format, tagged, and included in the TalkBank corpora. We also administered a written cloze task. Despite task variations, we find strong evidence that supported the influence of lexical semantics in Arabic learners’ acquisition of past tense marking, confirming the predictions of the Aspect Hypothesis.
A corpus study of Chinese EFL learners’ use of circumstance, demand, and significant
Authors: Liu Dilin 
Published: August 2018

Abstract
This study investigated Chinese EFL learners’ use of circumstance, demand, and significant, three
challenging words each being a member in a synonym set: circumstance in the
case/circumstance/event/situation set, demand in the
ask/demand/request/require set, and significant in the
important/meaningful/significant set. Via an expert rating and a close examination of all the uses of the
three words in Wen, Wang, and Liang’s (2005) Spoken and Written English Corpus of
Chinese Learners, the study has uncovered various inappropriate usages as well as successfully acquired usages involving the three
words. The results reveal a failure by many Chinese EFL learners to understand the three words’ semantic usage differences with
their respective synonyms. The study has also identified L1 interference, inadequate descriptions of these words in dictionaries,
and insufficient instructional attention to the semantic usage differences among synonyms as likely reasons for the learners’
inappropriate usages. Pedagogical and research implications are also discussed.
Le marquage du nombre (et du genre) en Normandie
Authors: Brasseur Patrice 
Published: August 2018

Résumé
Cet article porte sur le singulier et le pluriel des noms en -et comme bouquet dans les parlers
dialectaux normands. Le corpus est issu des atlas linguistiques, qui font au préalable l’objet d’une analyse
critique. L’opposition de -et/-ets se manifeste le plus souvent par l’aperture et la longueur de
la voyelle, selon différentes combinaisons, pouvant être regroupées dans quatre aires. Les résultats sont mis en perspective avec
les réalisations des participes passés en -é/-és/-ée/-ées. Malgré une situation complexe, on constate globalement
que le marquage porte sur le féminin singulier (vs. masculin) et sur le masculin pluriel (vs. singulier). Au total,
lorsqu’un allongement est réalisé, c’est toujours pour marquer le féminin et très souvent le pluriel, quoique les
différentes aires de -et/-ets et -é/-és ne se superposent que partiellement. On notera que la
situation dialectale se retrouve assez largement dans le français régional.
Contrastive analysis of interactional discourse markers in English and Spanish newspaper texts
Authors: Lavid-López Julia , Moratón Lara 
Published: August 2018

Abstract
This chapter reports on the contrastive analysis of interpersonal discourse markers (IDMs) in a sample of English and Spanish newspaper texts in three genres: news reports, editorials and letters to the editor. The sample was divided into a training dataset of eighteen (English-Spanish) comparable texts and a larger dataset of 220 texts, divided into 60 news reports, 60 editorials and 100 letters to the editor. Following the methodology of Hovy & Lavid (2010), we present a preliminary annotation scheme validated by an inter-annotation agreement study. We then present the results of annotating the larger dataset, which reveals genre-related and language-specific variation in the distribution of IDMs in these newspaper genres. We discuss and provide some possible explanations for the results obtained.
Empathy versus engagement
Authors: Martínez Maria-Ángeles 
Published: August 2018

Abstract
This study uses one of Hemingway’s very short stories (“The shooting of the six Greek cabinet ministers”, 1924) to explore the connections between narrative engagement, emotion and the linguistic organization of narratives. The analysis is developed within the framework of storyworld possible selves (SPSs) (Martínez 2012, 2014, 2018) or blends of readers’ self-concept and the character construct of a narrative perspectivizer, be it the narrator or a focalizing character. In Hemingway’s story, emotions may seem to emerge from empathy towards the executed ministers; however, a closer look at the language of reference and deixis suggests that engagement and emotion are connected to the ethical conflict resulting from SPS blending and perspectival alignment with their executioners.
Two dimensions of language intensity in evaluative discourse
Authors: Liebrecht Christine , Hustinx Lettica , van Mulken Margot , Schellens Peter Jan 
Published: August 2018

Abstract
Language intensity has been investigated within several disciplines, such as linguistics, stylistics and social psychology, and from several approaches. As a result, a wide range of intensifying elements and effects have been identified. In this chapter, we demonstrate on the basis of a qualitative corpus-analytical study that two dimensions play a decisive role in the discrimination of intensified language: contextuality and semantic richness. Contextuality reflects the degree to which the intensifying meaning of an element depends on its context. Semantic richness describes the amount of meaningful information that an intensifying element contains on top of its intensification function. This chapter is a starting point for further research concerning the characteristics of language intensity. Our insights contribute to established approaches in corpus-analytical and stylistic research.
Does the adapted version of The Amazing Race (AVOTAR) benefit Spanish language learning among technical students?
Authors: Khong Hou Keat , Cheah Swi Ee , Wan Nurul Na’imy , Martínez Vellón Susana 
Published: August 2018

Abstract
Students’ lack of interest and motivation in language learning has long been the focus of language scholars and researchers. In the Malaysian Technical and Vocational Education and Training (TVET) context, this concern has posed many practical challenges particularly to the foreign language teachers. This study proposes a teaching innovation adapted from the popular reality television program, The Amazing Race, to instill and promote interest in learning Spanish among the technical students. The study on the Adapted Version of The Amazing Race (AVOTAR) was conducted using a quantitative dominant mixed methods approach in a technical university where Spanish language is a compulsory subject. The quantitative findings show that AVOTAR improves learners’ linguistic performance especially in the areas of vocabulary and reading comprehension while the qualitative findings indicate that AVOTAR helps increase learners’ motivation. This may contribute useful insights to address the challenges and improve the curriculum and instruction of foreign languages.
A relational adjective and a noun semantic binding in the specialized language of Information and Communication Technology
Authors: López Hernández Francisca , Bernardos Galindo Socorro 
Published: August 2018

AbstractThis study reports on a semantic analysis of a terminology pattern formed by a relational adjectiveRadjand a nounn, found in specialized texts written in English and Spanish from the Information and Communication Technology (ICT) field. This research is first based on a terminology perspective to later focus on a recurring multi-word lexical unit pattern in which the specialized concept is realized by a relational adjective. The syntactic pattern [Radj+n] will be referred to as Specialized Lexical Combination (SLC). The study presents a step forward to previous terminology research. We argue that the semantic analysis of the adjective-noun relationship will help understand the underlying knowledge organization of this ICT subject area. The analysis is approached from the framework of the Generative Lexicon specially focusing on thequaliastructure of this recurring multi-word lexical unit pattern.
Understanding the use of mediational means in academic writing
Authors: Wu Peisha , Yu Shulin 
Published: August 2018

Abstract
While the majority of previous studies on EAP (English for academic purposes) writing have been devoted to professional or academic writing at a more advanced level (i.e., PhD students and scholars) in ESL contexts, little attention has been paid to the academic writing of master-level novice writers in EFL contexts. From a sociocultural perspective, the present case study examined the writing strategies of a master-level novice writer – Alice in Macau context. Non-structured, semi-structured and text-based interviews were used as the primary source of data, with document analysis used for triangulation. The study identified two major categories (i.e., artifacts and community) and five subcategories of mediational means (i.e., journal articles and theses, languages, online writing materials, peers and experts) as significant in the novice writer’s academic writing activities. It also unveiled double-edged features of mediational means and recognized their interplay with the writer’s goals and relatedness to her situated context.