bluuebunny/crossref_metadata_2025_split huggingface dataset:
Taitsumanialuk, les collections de l’Arctique canadien et du Groenland dans les musées français au XIXe siècle
Authors: Guigon Gwénaële 
Published: September 2019

Dès le XIXe siècle, des artefacts arctiques figurent dans les inventaires des premiers musées publics français. Un certain nombre provenait de cabinets de curiosités privés, nationalisés lors de la Révolution française. Si la France n’a jamais manifesté d’intérêt particulier et encore moins de velléité territoriale sur les zones arctiques, on trouve néanmoins des objets Inuit conservés dans nombre d’institutions muséales sur le territoire. Ces collections sont arrivées sur le sol français grâce à l’intérêt de particuliers, collectionneurs et voyageurs, ainsi qu’aux échanges avec des institutions étrangères. En petit nombre au sein des musées encyclopédiques, elles ne furent que très rarement étudiées, bien qu’exposées régulièrement au public. Achetées à des intermédiaires et souvent vendues sous le terme de pièces « eskimos », malgré quelques exceptions notoires, une grande majorité fut enregistrée dans les inventaires sans que le contexte d’origine n’apparaisse. Il faut véritablement attendre le dernier tiers du XIXe siècle pour découvrir, en France, des artefacts reproduits dans des revues scientifiques à travers le prisme de l’anthropologie physique et surtout de l’archéologie. La collection la plus vaste et la plus connue se trouve aujourd’hui conservée au musée du quai Branly-Jacques Chirac, à Paris. Pourtant, une dizaine de villes françaises possède également des collections issues des régions polaires. La majorité de ces objets est arrivée en France avant la Seconde Guerre mondiale. Il faut cependant attendre les années 2000 pour appréhender l’ampleur de ces collections sur tout le territoire français, malgrés des recherches isolées et des initiatives particulières qui ont mis en lumière localement ces objets. Cet article vise à analyser et documenter les collections arctiques du XIXe siècle en France, dans une perspective historique.
No deal! Sweden cancelled agreement with Elsevier to stand up for Open Science
Authors: Heyman Widmark Cecilia , Hamrin Göran 
Published: September 2019

In this talk we highlight some results after the Swedish Bibsam consortium decided to cancel the agreement with scientific publisher Elsevier after 20 years as they couldn’t present a model that met the demands of the consortium.
The requirements were immediate open access to all articles published in Elsevier journals by researchers affiliated to participating organisations as well as reading access to all articles in Elsevier’s journals. Bibsam also demanded a sustainable price model that enables a transition to open access publishing. We investigate the effects of this cancellation on Sweden’s largest technical university, the KTH Royal Institute of Technology.
Method
The study has two themes. First, we analyse the economics in earlier Bibsam-Elsevier agreements and what effects they have had for the budget and purchasing decisions made by the KTH Library. Second, we evaluate the response and the adapted behaviour of KTH researchers in the attempt to see if the cancellation has had severe negative effects for them.
Results
Our data collection gives an overview over the effects of the cancelled agreement at KTH. In particular, we observe how some of the money saved on the cancellation is used for individual article purchases and alternative services, thus lowering the effect of the cut-off. During our talk, we will also review some marketing strategies employed at KTH and Swedish libraries for making this cancellation process as smooth as possible.
Limitations
The short time period that has elapsed after the cancellation makes it difficult to see any long-time trends. The limited time frame also affects the validity of the researchers’ responses. Moreover, it is difficult to tell how the results from a case study from one university can be generalised to a global setting.
Scanning Probe Lithography Patterning of Monolayer Semiconductors and Application in Quantifying Edge Recombination
Authors: Zhao Peida , Wang Ruixuan , Lien Der‐Hsien , Zhao Yingbo , Kim Hyungjin , Cho Joy , Ahn Geun Ho , Javey Ali 
Published: September 2019

AbstractScanning probe lithography is used to directly pattern monolayer transition metal dichalcogenides (TMDs) without the use of a sacrificial resist. Using an atomic‐force microscope, a negatively biased tip is brought close to the TMD surface. By inducing a water bridge between the tip and the TMD surface, controllable oxidation is achieved at the sub‐100 nm resolution. The oxidized flake is then submerged into water for selective oxide removal which leads to controllable patterning. In addition, by changing the oxidation time, thickness tunable patterning of multilayer TMDs is demonstrated. This resist‐less process results in exposed edges, overcoming a barrier in traditional resist‐based lithography and dry etch where polymeric byproduct layers are often formed at the edges. By patterning monolayers into geometric patterns of different dimensions and measuring the effective carrier lifetime, the non‐radiative recombination velocity due to edge defects is extracted. Using this patterning technique, it is shown that selenide TMDs exhibit lower edge recombination velocity as compared to sulfide TMDs. The utility of scanning probe lithography towards understanding material‐dependent edge recombination losses without significantly normalizing edge behaviors due to heavy defect generation, while allowing for eventual exploration of edge passivation schemes is highlighted, which is of profound interest for nanoscale electronics and optoelectronics.
A fast‐moving target: achieving marine conservation goals under shifting climate and policies
Authors: Rilov Gil , Fraschetti Simonetta , Gissi Elena , Pipitone Carlo , Badalamenti Fabio , Tamburello Laura , Menini Elisabetta , Goriup Paul , Mazaris Antonios D. , Garrabou Joaquim , Benedetti‐Cecchi Lisandro , Danovaro Roberto , Loiseau Charles , Claudet Joachim , Katsanevakis Stelios 
Published: September 2019

AbstractIn the Anthropocene, marine ecosystems are rapidly shifting to new ecological states. Achieving effective conservation of marine biodiversity has become a fast‐moving target because of both global climate change and continuous shifts in marine policies. How prepared are we to deal with this crisis? We examined EU Member States Programs of Measures designed for the implementation of EU marine environmental policies, as well as recent European Marine Spatial Plans, and discovered that climate change is rarely considered operationally. Further, our analysis revealed that monitoring programs in marine protected areas are often insufficient to clearly distinguish between impacts of local and global stressors. Finally, we suggest that while the novel global Blue Growth approach may jeopardize previous marine conservation efforts, it can also provide new conservation opportunities. Adaptive management is the way forward (e.g., preserving ecosystem functions in climate change hotspots, and identifying and targeting climate refugia areas for protection) using Marine Spatial Planning as a framework for action, especially given the push for Blue Growth.
The kinetics and mechanism of polymer‐based NHC‐Pd‐pyridine catalyzed heterogeneous Suzuki reaction in aqueous media
Authors: Boztepe Cihangir , Künkül Asım , Gürbüz Nevin , Özdemir İsmail 
Published: September 2019

AbstractOne of the most important challenges of the Suzuki reaction is a green synthesis of reaction products. In terms of economy and ecology, the Suzuki reaction details must be characterized for the industrial‐scale Suzuki reaction processes. In this paper, for the first time, a kinetic and mechanistic study on the Suzuki reaction catalyzed with hydrogel‐supported PEPPSI (pyridine‐enhanced precatalyst preparation stabilization (and) initiation) type NHC‐Pd‐pyridine composite has been investigated. To determine the rate‐limiting step, the effects of reactants and experimental conditions on the heterogeneous Suzuki reaction have been experimentally defined. The experimental results demonstrated that it is possible to reach 100% yield under the optimum reaction conditions, which were found as 75 × 10−3 mol/L of phenylboronic acid (FBA), 50 × 10−3 mol/L of bromoacetophenone (Brac), 125 × 10−3 mol/L of K2CO3, 1 g/L of catalyst, 80°C of reaction temperature, 400 rpm of mixing rate, and 3 h of reaction time. The transmetalation step in the cycle was defined as the rate‐limiting step. On the basis of kinetic results, a mathematical reaction rate expression was presented assuming the steady‐state approach to steps of the catalytic cycle. The activation energy (Ea) of the reaction was estimated to be 34.88 kJ/mol.
A New Associative Diblock Copolymer of Poly(ethylene glycol) and Dense 1,2,3‐Triazole Blocks: Self‐Association Behavior and Thermoresponsiveness in Water
Authors: Yang Yanqiong , Hashidzume Akihito 
Published: September 2019

AbstractIn this work, new diblock copolymers of poly(ethylene glycol) (PEG) and dense 1,2,3‐triazole blocks (EGm‐b‐APn and EGm‐b‐ABn, where m and n denote the degrees of polymerization), are synthesized by copper(I)‐catalyzed azide–alkyne cycloaddition polymerization of 3‐azido‐1‐propyne (AP) and 3‐azido‐1‐butyne (AB), respectively, in the presence of PEG possessing a propargyl group. Their self‐association behavior and thermoresponsive property in water are investigated. The characterization data indicate that EG45‐b‐AP6 and EG45‐b‐AP14 form dominantly spherical micelles, EG18‐b‐AP4 and EG18‐b‐AP10 form vesicles, and EG18‐b‐AB7 forms rodlike micelles. Aqueous solutions of EG18‐b‐AP10, EG45‐b‐AP14, and EG18‐b‐AB7 undergo lower critical solution temperature (LCST)‐type phase separation. The thermoresponsive association behavior can be controlled by adjusting the ratio of block lengths and by attaching methyl substituents.
Efficacy and Tolerance of Blended Diets in Children Receiving Gastrostomy Feeds
Authors: Batsis Irini D. , Davis Laura , Prichett Laura , Wu Linxuan , Shores Darla , Au Yeung Karla , Oliva‐ Hemker Maria 
Published: September 2019

AbstractBackgroundTo determine the prevalence of gastrointestinal (GI) symptoms in children receiving a blended diet via a gastrostomy tube.MethodsThis is a single‐center, retrospective study of children ages 1–18 years that received a blended diet. We reviewed demographics, anthropometrics, clinical characteristics, and rationale for switching to blended diet. Fixed‐effects logistic regression analysis was used to evaluate the changes in patient symptoms over the 12‐month follow‐up period, and fixed‐effects regression was employed to test for changes in anthropometrics.ResultsTwenty‐three patients (8 female, 15 male) were identified, and data from 89 outpatient visits were analyzed. The most common underlying diagnosis was neurological disorder. Thirty‐five percent of patients received commercial whole cow milk formulas, 30% received hydrolysate formulas, and 35% received amino acid−based formulas. After formula switches were made, 65% received homemade blended diets, 17.5% received commercial blended diets, and 17.5% received a combination of both. Median duration of time on a blended diet was 17 months. Ninety‐five percent of patients who were previously experiencing upper GI symptoms improved within the first 3 months after blended diet initiation. Twenty‐one percent of patients developed mild constipation on the diet, which was managed with increased water intake and/or polyethylene glycol. Only 2 patients discontinued the blended diet, because of inadequate weight gain and worsening of upper GI symptoms.ConclusionsIn our study population, blended diets were well tolerated in gastrostomy‐fed children and were associated with clinical improvement of upper GI symptoms.
Making Brexit work for the environment and livelihoods: Delivering a stakeholder informed vision for agriculture and fisheries
Authors: Stewart Bryce D. , Burns Charlotte , Hejnowicz Adam P. , Gravey Viviane , O’Leary Bethan C. , Hicks Kevin , Farstad Fay M. , Hartley Sue E. 
Published: September 2019

Abstract

The decision of the UK to leave the EU has far‐reaching, and often shared, implications for agriculture and fisheries. To ensure the future sustainability of the UK’s agricultural and fisheries systems, we argue that it is essential to grasp the opportunity that Brexit is providing to develop integrated policies that improve the management and protection of the natural environments, upon which these industries rely.

This article advances a stakeholder informed vision of the future design of UK agriculture and fisheries policies. We assess how currently emerging UK policy will need to be adapted in order to implement this vision. Our starting point is that Brexit provides the opportunity to redesign current unsustainable practices and can, in principle, deliver a sustainable future for agriculture and fisheries.

Underpinning policies with an ecosystem approach, explicit inclusion of public goods provision and social welfare equity were found to be key provisions for environmental, agricultural and fishery sustainability. Recognition of the needs of, and innovative practices in, the devolved UK nations is also required as the new policy and regulatory landscape is established.

Achieving the proposed vision will necessitate drawing on best practice and creating more coherent and integrated food, environment and rural and coastal economic policies. Our findings demonstrate that “bottom‐up” and co‐production approaches will be key to the development of more environmentally sustainable agriculture and fisheries policies to underpin prosperous livelihoods.

However, delivering this vision will involve overcoming significant challenges. The current uncertainty over the nature and timing of the UK’s Brexit agreement hinders forward planning and investment while diverting attention away from further in‐depth consideration of environmental sustainability. In the face of this uncertainty, much of the UK’s new policy on the environment, agriculture and fisheries is therefore ambitious in vision but light on detail. Full commitment to co‐production of policy with devolved nations and stakeholders also appears to be lacking, but will be essential for effective policy development and implementation.

A free Plain Language Summary can be found within the Supporting Information of this article.
A Review of Clinical Pharmacokinetic and Pharmacodynamic Profiles of Select Antiretrovirals: Focus on Differences among Chinese Patients
Authors: Du Xiaoli , Peng Wenxiu , Fu Qiang , Ma Qing , Zhu Zhu , Li Taisheng 
Published: September 2019

ObjectiveTo identify the pharmacokinetic differences of antiretroviral drugs between HIV‐infected Chinese patients and patients of other race/ethnicities.Study DesignResults from prospective, open‐label pharmacokinetic studies among Chinese and historical data from other race/ethnicities.PatientsPharmacokinetics of six commonly used antiretroviral drugs, including zidovudine, lamivudine, tenofovir disoproxil fumarate, nevirapine, efavirenz and lopinavir/ritonavir, was evaluated in HIV‐infected Chinese patients and compared with historical data from other race/ethnicities.AnalysisPharmacokinetic analyses were performed at the steady state among HIV‐infected Chinese patients. Safety data were collected during the follow‐up. The pharmacokinetic parameters including maximal concentrations (Cmax), area‐under‐curve (AUC) and clearance (Cl/F) from the Chinese patients were compared to the historic data from other race/ethnicities.ResultsCurrent evidence, though limited, suggested that these antiretroviral agents were generally safe and effective among HIV‐infected Chinese patients. However, compared with other racial groups, Chinese patients exhibited higher Cmax, AUC and lower Cl/F for most of the agents, and the incidences of adverse reactions, for example, liver toxicity, rash, and bone health, were more frequent.ConclusionsThese pharmacokinetic differences suggest that lower dosages for commonly prescribed antiretroviral drugs in China might be appropriate to reduce drug‐related adverse reactions, while maintain the antiviral efficacy.
When Did Life Likely Emerge on Earth in an RNA‐First Process?
Authors: Benner Steven A. , Bell Elizabeth A. , Biondi Elisa , Brasser Ramon , Carell Thomas , Kim Hyo‐Joong , Mojzsis Stephen J. , Omran Arthur , Pasek Matthew A. , Trail Dustin 
Published: September 2019

AbstractThe widespread presence of ribonucleic acid (RNA) catalysts and cofactors in the Earth′s biosphere today suggests that RNA was the first biopolymer to support Darwinian evolution. However, most “path‐hypotheses” to generate building blocks for RNA require reduced nitrogen‐containing compounds not made in useful amounts in the CO2−N2−H2O atmospheres of the Hadean. We review models for Earth′s impact history that invoke a single ∼1023 kg impactor (Moneta) to account for measured amounts of platinum, gold, and other siderophilic (“iron‐loving”) elements on the Earth and Moon. If it were the last sterilizing impactor, by reducing the atmosphere but not the mantle Moneta, would have opened a “window of opportunity” for RNA synthesis, a period when RNA precursors rained from the atmosphere onto land holding oxidized minerals that stabilize advanced RNA precursors and RNA. Surprisingly, this combination of physics, geology, and chemistry suggests a time when RNA formation was most probable, ∼120±100 million years after Moneta′s impact, or ∼4.36±0.1 billion years ago. Uncertainties in this time are driven by uncertainties in rates of productive atmosphere loss and amounts of sub‐aerial land.
Cognitive functioning and predictors thereof in patients with 1–10 brain metastases selected for stereotactic radiosurgery
Authors: Schimmel Wietske C. M. , Gehring Karin , Hanssens Patrick E. J. , Sitskoorn Margriet M. 
Published: September 2019

AbstractPurposeInformation on predictive factors of cognitive functioning in patients with (multiple) brain metastases (BM) selected for radiosurgery may allow for more individual care and may play a role in predicting cognitive outcome after radiosurgery. The aim of this study was to evaluate cognitive performance, and predictors thereof, in patients with 1–10 BM before radiosurgery.MethodsCognition was measured before radiosurgery using a standardized neuropsychological test battery in patients with 1–10 BM (expected survival > 3 months; KPS ≥ 70; no prior BM treatment). Regression formulae were constructed to calculate sociodemographically corrected z scores. Group and individual cognitive functioning was analyzed. Multivariable regression was used to explore potential predictors.ResultsPatients (N = 92) performed significantly worse than controls (N = 104) on all 11 test variables (medium-large effect sizes for 8 variables). Percentages of impairment were highest for information processing (55.3%), dexterity (43.2%) and cognitive flexibility (28.7%). 62% and 46% of patients had impairments in at least two, or three test variables, respectively. Models including combinations of clinical and psychological variables were predictive of verbal memory, psychomotor speed, information processing and dexterity. Neither number nor volume of metastases predicted patients’ test performance.ConclusionsAlready before radiosurgery, almost half of the patients suffered from severe cognitive deficits in at least three test variables. At group and individual level, information processing, cognitive flexibility, and dexterity were most affected. These cognitive impairments may impair daily functioning and patients’ ability to make (shared) treatment decisions. Both clinical (symptomatic BM; timing of BM diagnosis) and psychological (mental fatigue) characteristics influenced cognitive performance.Clinical trial informationCognition and Radiation Study A (CAR-Study A; ClinicalTrials.gov Identifier: NCT02953756; Medical Ethics Committee file number: NL53472.028.15/P1515).
Coordination, cooperation and collaboration in relief supply chain management
Authors: Wankmüller Christian , Reiner Gerald 
Published: September 2019

AbstractIn recent years, an increasing number of natural and man-made disasters has demonstrated that a working relief supply chain management (RSCM) is crucial in order to alleviate the suffering of the affected population. Coordination, cooperation and collaboration within RSCM is essential for overcoming these destructive incidents. This paper explores the research undertaken in recent years, focusing on coordination, cooperation and collaboration in the field of supply chain management (SCM) and RSCM in order to provide unique definitions of these concepts taking the disaster setting into consideration. A systematic literature review including 202 academic papers published from 1996 onwards in top journals dealing with commercial supply and relief supply chain coordination, cooperation and collaboration is applied. In order to answer the underlying research questions in a proper way, a descriptive analysis and qualitative and quantitative content analysis of the papers are conducted. Descriptive results indicate that RSCM coordination, cooperation and collaboration have increasingly shifted into the focus of scientific research since 2001/2004 (i.e., 9/11 and the Indian Ocean Tsunami). Based on the qualitative content analysis, clear definitions of the terms coordination, cooperation and collaboration in SCM and RSCM were elaborated. The research landscape, as a result of the quantitative content analysis, allowed the identification of three issues that need to be addressed in future research work.
The Utility of Diffusion-Weighted Imaging and Perfusion Magnetic Resonance Imaging Parameters for Detecting Clinically Significant Prostate Cancer
Authors: Cindil Emetullah , Oner Yusuf , Sendur Halit Nahit , Ozdemir Hakan , Gazel Eymen , Tunc Lutfi , Cerit Mahi Nur 
Published: September 2019

Introduction To establish the diagnostic performance of the parameters obtained from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging at 3T in discriminating between non-clinically significant prostate cancers (ncsPCa, Gleason score [GS] < 7) and clinically significant prostate cancers (csPCa, GS ≥ 7) in the peripheral zone. Materials and Methods Twenty-six male patients with peripheral zone prostate cancer (PCa) who had undergone 3T multiparametric magnetic resonance imaging (MRI) scan prior to biopsy were included in the study and evaluated retrospectively. The GS was obtained by both standard 12-core transrectal ultrasound guided biopsy and targeted MRI-US fusion biopsy and then confirmed by prostatectomy, if available. For each confirmed tumour focus, DCE-derived quantitative perfusion metrics (Ktrans, Kep, Ve, initial area under the curve [AUC]), the apparent diffusion coefficient (ADC) value, and normalized versions of quantitative metrics were measured and correlated with the GS. Results Ktrans had the highest diagnostic accuracy value of 82% among the DCE-MRI parameters (AUC 0.90), and ADC had the strongest diagnostic accuracy value of 87% among the overall parameters (AUC 0.92). The combination of ADC and Ktrans have higher diagnostic performance with the area under the receiver operating characteristic curve being 0.98 (sensitivity 0.94; specificity 0.89; accuracy 0.92) compared to the individual evaluation of each parameter alone. The GS showed strong negative correlations with ADC (r = −0.72) and normalized ADC (r = −0.69) as well as a significant positive correlation with Ktrans (r = 0.69). Conclusion The combination of Ktrans and ADC and their normalized versions may help differentiate between ncsPCa from csPCa in the peripheral zone.