bluuebunny/crossref_metadata_2025_split huggingface dataset:
INCREASING THE VISIBILITY DURING INTERNAL LIMITING MEMBRANE PEELING IN VITRECTOMY SURGERY
Authors: Matsumoto Keiji , Sakanishi Yoshihito , Fujii Tatsuya , Usui-Ouchi Ayumi , Sakuma Toshiro , Ebihara Nobuyuki 
Published: November 2024

Purpose:
The aim of the study is to explore the effectiveness of using monochrome mode with Brilliant Blue G during vitrectomy surgery with the NGENUITY 3D Visualization System.

Methods:
Vitrectomy cases involving BBG-stained internal limiting membrane peeling with the NGENUITY 3D Visualization System (Alcon Laboratories, Inc.) at Juntendo University Urayasu Hospital from October 2022 to February 2023 were selected. The contrast ratios between peeled and stained internal limiting membrane areas under three settings were assessed: normal, yellow, and monochrome. In the monochrome setting, a yellow hue was used with zero saturation, while the Friedman test compared these ratios.

Results:
Nineteen patients (19 eyes; 7 males, 12 females; average age 68.5 ± 10.3 years) with retinal conditions such as epiretinal membrane (n = 11), macular hole (n = 4), macular traction syndrome (n = 3), and retinoschisis (n = 1) were included. We obtained contrast ratios of 1.57 ± 0.21 (normal), 1.60 ± 0.21 (yellow), and 1.92 ± 0.29 (monochrome). The monochrome setting showed significantly higher contrast than that shown by the normal and yellow settings (P = 0.0001, P = 0.0005), with no difference between the normal and yellow settings (P = 0.903).

Conclusion:
Monochrome mode in NGENUITY with Brilliant Blue G potentially enhances contrast and increases visibility during internal limiting membrane peeling.
SPLIT OUTER PLEXIFORM LAYER APPEARANCE REPRESENTS AN ACQUIRED CONE DYSFUNCTION PHENOTYPE OF AUTOIMMUNE RETINOPATHY
Authors: Boyce Timothy M. , Fortenbach Christopher , Thurtell Matthew , Stone Edwin M. , Han Ian C. 
Published: November 2024

Purpose:
Autoimmune retinopathy (AIR) is a poorly understood condition with a wide phenotypic spectrum and heterogeneous findings on clinical examination and imaging. In this study, the authors characterize the clinical features of a recently described phenotypic subtype of AIR with a distinct split outer plexiform layer appearance on OCT.

Methods:
This was a retrospective, observational study of patients with a diagnosis of AIR seen at the University of Iowa between January 2007 and September 2023 who were found to have decreased visual acuity, central scotoma on visual field testing, split outer plexiform layer appearance on OCT, and abnormal light-adapted electroretinogram, consistent with an acquired cone dysfunction. Clinical course and multimodal imaging and physiologic testing were reviewed.

Results:
Ten patients were identified in the retrospective cohort. All patients presented with bilateral, asymmetric, subacute, and progressive central vision loss. A diagnosis of cancer was present or subsequently diagnosed in 5 out of 10 patients (50%). Overall, 40% of patients underwent treatment with immunosuppressives, and one patient underwent tumor resection, with partial visual recovery seen.

Conclusion:
Patients with split outer plexiform layer appearance on OCT have an acquired cone dysfunction that is important to recognize as treatment in some cases may result in improved or stabilized visual function.
Scleral Contact Lens Benefits for Myopic Patients With Regular Corneas: A Prospective Randomized Study
Authors: Liang Ruixue , Li Na , Liu Lin , Du Bei , Pazo Eric , Wei Ruihua 
Published: November 2024

Objectives:
To evaluate the impact of scleral contact lens (SL) wear on the visual quality and the ocular surface wettability in myopic patients with regular corneas.

Methods:
This prospective, randomized, controlled study enrolled a total of 80 myopes with regular corneas. Subjects were randomly allocated to wear SL or rigid corneal lens (RCL) for 3 months. The objective optical quality parameters were detected using the Optical Quality Analysis System-II, and the ocular surface wettability was assessed using the Keratograph 5M noninvasive ocular surface analyzer. The National Eye Institute 25-Item Visual Function Questionnaire and Ocular Surface Disease Index questionnaire were performed.

Results:
Both SL and RCL wear could obtain good best-corrected visual acuity. Strehl ratio, modulation transfer function cutoff frequency, objective scattering index, and Optical Quality Analysis System values (Optical Quality Analysis System values at 100%, 20%, and 9% contrasts) in the SL group significantly improved from baseline to the third month (both P<0.05), but not in the RCL group. At the third month, tear meniscus height and noninvasive tear break-up time showed a significant increase in the SL wearers from baseline (both P<0.05), but exhibited no significant changes in the RCL group. At the third month, SL wearers had significantly higher noninvasive tear break-up time compared with RCL wearers (P<0.05). Besides, after 3-month SL wear, the National Eye Institute 25-Item Visual Function Questionnaire score and the Ocular Surface Disease Index score both remarkably improved from baseline (both P<0.05).

Conclusion:
Short-term SL wear could provide satisfactory visual quality, ocular comfort, and stable tear film for myopic patients.
Developmental Delay With Increasing Trend During 2019–2022 in Mexican Children Under 5 Years
Authors: Rodríguez-Vidales Edgar P. , Santos-Flores Izamara , Santos-Flores Jesús M. , Garza-Rodríguez Mara I. , Alvarado-Medina Ofelia M. , Garza-Carrillo Denise , Montes de Oca-Luna Roberto , Marroquín-Escamilla Alma R. 
Published: November 2024

Despite its importance, studies involving developmental delay remain low in the last 10 years in Latin. The objective of the present study was to estimate and compare the prevalence of developmental delay during 2019–2022 in Mexican children under 5 years of age. This was a cross-sectional study carried out in Nuevo Leon, Mexico (n = 2,951). Developmental delay was measured with the Prueba de Desarrollo Infantil screening test. Point prevalence and 95% confidence interval (CI) were estimated globally, per area, and per year. The association of sex and children’s age to developmental delay was evaluated with binary logistic regression analysis. The prevalence of developmental delay was 42.1% (95% CI: 40.3–43.9). An upward trend was identified; prevalence reached 76% at the end of the study period. Alarm signs and language registered the highest prevalence. Being male doubled the chances of developmental delay (odds ratio 2.2, 95% CI: 1.9–2.6), and having 2.0–2.9 years increased seven times the possibilities of developmental delay (odds ratio 6.7, 95% CI: 5.3–8.7). Findings highlight the challenge that the health sector faces to stop and reverse the developmental delay statistics.
Technical means of preventing and treating anastomotic leakage after colorectal surgery: A review
Authors: Zhao Lu , Wang Fei , Chen Jian-Hua , Wei Chen , Ma Yi-Chao , Ji Hao , Zhao Jia-Hao , Tang Dong 
Published: November 2024

Abstract
With its significant morbidity and mortality, anastomotic leaking is a serious concern in the field of colorectal surgical treatments. A number of strategies and actions have been introduced in the last few years with the goal of reducing the incidence of this surgical complication and the clinical consequences that follow. Based on the most recent academic research, this article aims to provide a comprehensive assessment of the current approaches for the prevention and management of anastomotic leakage in the context of colorectal cancer surgeries. In addition to encouraging more study and innovation in this crucial field, the aim is to provide useful insights and references for clinical practices in the prevention and treatment of anastomotic leakage.
Exploring the Relationship Between eHealth Literacy and Diabetes Knowledge, Self-Efficacy, and Self-Care Behaviors in Chinese Diabetic Patients: A Cross-Sectional Study
Authors: JI Xing , CHI Juntao 
Published: November 2024

ABSTRACT

Background
The importance of online educational resources enhancing self-management among patients is underscored by the growing prevalence of diabetes. It is crucial to comprehend how patients with diabetes in China seek diabetes-related information and use mobile applications (apps) designed for diabetes management. Although the Knowledge-Attitude-Practice theory plays an integral role in diabetes management, in-depth studies on eHealth literacy (eHL) and Knowledge-Attitude-Practice in populations with diabetes remain scarce.

Purpose
This study was developed to provide insights into the online information-seeking behaviors of and diabetes apps used by individuals living with diabetes by exploring the relationships among eHL, diabetes knowledge, self-efficacy, and self-care behaviors.

Methods
A cross-sectional survey was conducted from November 2022 to June 2023 on 380 inpatients with diabetes at the Yantai Yuhuangding Hospital in Shandong Province. The participants voluntarily completed surveys covering sociodemographic characteristics, diabetes status, diabetes app usage, online diabetes information searching, eHL, diabetes knowledge, self-efficacy, and self-care behaviors. Structural equation modeling analyses were employed to assess model fitness and the interrelationships between latent constructs and observable variables.

Results
Of the 380 participants, 57.1% (217/380) reported actively seeking diabetes information online, whereas only 3.7% (14/380) had used diabetes apps. eHL was shown to have a direct effect on diabetes knowledge (β = 0.377, p < .001) but no direct impact on self-care behaviors (β = 0.017, p = .860). However, an indirect effect on self-care behaviors was observed via diabetes knowledge and self-efficacy.

Conclusions/Implications for Practice
The results of this study indicate that, despite widespread online information-seeking behavior, diabetes app utilization remains limited in China. Also, the findings indicate enhancing patients' eHL contributes to more comprehensive diabetes knowledge. Furthermore, eHL was shown to influence self-care behaviors via diabetes knowledge and self-efficacy. A self-managed intervention strategy should be developed to improve eHL that utilizes internet resources to improve patients' knowledge and self-efficacy and promote better self-care behaviors.
Work Functioning Impairment and Telework
Authors: Yoshida Ai , Okawara Makoto , Matsugaki Ryutaro , Nagata Tomohisa , Tateishi Seiichiro , Eguchi Hisashi , Tsuji Mayumi , Matsuda Shinya , Fujino Yoshihisa ,   for the CORoNaWork Project
Published: November 2024

Objectives
To clarify the association between telework with family members at home and work functioning impairment.

Methods
A cross-sectional survey was conducted in 27,036 participants. Having children or cohabitants in need of care at home during telework was considered an exposure factor. Multilevel logistic regression analysis was used to calculate odds ratios (ORs) for work functioning impairment, assessed by The Work Functioning Impairment Scale (WFun).

Results
Participants living with cohabitants in need of care at home had higher odds of work functioning impairment, whereas those living with preschool children or a spouse had lower odds. Participants living with children or cohabitants in need of care at home during telework had higher odds.

Conclusions
We found an association between having children or cohabitants in need of care at home during telework and work functioning impairment.
Assessing the Impact of the COVID-19 Pandemic on Small and Medium Businesses in North Carolina
Authors: McAden Emily P. , Leff Maija S. , Jardel Hanna V. , Greenberg Rosa W. , Staley John A. , Linnan Laura A. , Nylander-French Leena A. 
Published: November 2024

Objective
As the COVID-19 pandemic presented new challenges for businesses and worker safety and health, an interdisciplinary team launched the COVID-19 Worksite Impact Survey to assess COVID-19–related impacts and responses at small and medium businesses in 10 North Carolina counties.

Methods
We collected data from October 2 to December 1, 2020, and analyzed survey results to evaluate businesses' operational changes, concerns, needs, pandemic preparedness, workplace health promotion programming, and infection control practices.

Results
Most businesses, including essential ones, were inadequately prepared for the pandemic and did not implement the most effective COVID-19 infection control practices. Larger businesses and those with existing preparedness practices or health promotion programs were more likely to implement effective measures.

Conclusions
We should be acting now to improve small and medium businesses' preparedness for future public health crises.
Multicontextual Factors That Influence Work-Life Balance of Family Caregivers of Adults With Parkinson’s Disease
Authors: Hellmers Natalie , Stimpfel Amy Witkoski , Fletcher Jason , Dickson Victoria Vaughan 
Published: November 2024

Objective
The purpose of study was to explore family caregiver perspectives on work-life balance while caring for adults with Parkinson’s disease.

Methods
The study was performed using a convergent mixed methods design and a revised adaptation of the Work-Life Conflict model. Caregivers completed surveys followed by semistructured interviews (n = 40).

Results
Work-life balance is bidirectionally influenced by time, stress, and behavior across the working and caregiving role. Caregiver burden was offset by higher decision latitude at work. Supervisor support and coworker support were positively associated with work-life balance. Barriers included physical, emotional, and financial stress, and speech and cognitive changes of the care recipient.

Conclusions
The results of this study identify the influence of work-life imbalance on caregiver burden and stress, and generate discussion of potential solutions that optimize well-being and health of this working population.
Analgesia After Vestibular Schwannoma Surgery in Europe—Potential for Reduction of Postoperative Opioid Usage
Authors: Gerlitz Matthias , Yildiz Erdem , Dahm Valerie , Herta Johannes , Matula Christian , Roessler Karl , Arnoldner Christoph , Landegger Lukas D. 
Published: November 2024

Objective
Excessively prescribed opioids promote chronic drug abuse and worsen a highly prevalent public health problem in the era of the opioid epidemic. This study aimed to (a) determine general analgesic prescription patterns after surgery for vestibular schwannoma (VS) with a focus on opioid prescription rates, (b) identify risk factors for receiving narcotics for postoperative pain management, and (c) highlight the feasibility of opioid-free analgesic treatment strategies.

Study Design
Retrospective chart review.

Setting
Tertiary referral center.

Patients
A total of 105 adult inpatients who underwent VS surgery.

Interventions
Analgesic prescription patterns were evaluated, and factors associated with opioid prescriptions were identified.

Main outcome measure
Number of prescribed analgesics.

Results
Metamizole (=dipyrone) and acetaminophen (=paracetamol) were the most frequently prescribed non-opioid drugs. Sixty-three (60%) patients received an opioid with a median intake of 23.2 ± 24 mg of oral morphine equivalents. Only 10 (9.5%) individuals received opioids for longer than postoperative day 1. Subjects with small tumors undergoing middle cranial fossa tumor removal (p = 0.007) were more likely to receive opioid drugs. In contrast, patients undergoing retrosigmoid craniotomy required fewer opioids for pain control (p = 0.004). Furthermore, individuals receiving opioids were prone to obtain higher dosages of acetaminophen (odds ratio 1.054, 95% confidence interval 1.01–1.10, p = 0.022).

Conclusions
Opioids for acute postoperative analgesia after VS surgery may be necessary in many patients. However, middle- and long-term pain control can be accomplished using non-opioid treatment regimens, resulting in a reduction in opioid prescriptions and the accompanying negative effects on individual and public health.
Efficient use of the TM-2441 ambulatory blood pressure measurement device in patients with diabetes
Authors: Cicco Sebastiano , Marozzi Marialuisa Sveva , Schirosi Gabriella , Corvasce Francesco , Romano Daniele Egidio , Vacca Angelo , Nazzaro Pietro 
Published: November 2024

Background and objective
Ambulatory blood pressure monitoring (ABPM) requires automatic measurement and the use of a validated device, according to current guidelines and international standardization. The TM-2441 (A&D Co. Ltd, Tokyo, Japan) ABPM device is small, lightweight, and suitable for use in ambulatory settings. It was validated against the ISO 81060-2:2013 standard in the general population. This study investigated the reliability of the ABPM device for patients with type 2 diabetes.

Methods
Individuals aged more than 12 years affected with type 2 diabetes were recruited by our outpatient clinic. The blood pressure assessment was performed using the opposite limb simultaneous measurement according to the updated ISO 81060-2:2018.

Results
Forty-five subjects were included in the clinical investigation. The mean difference between blood pressure values measured by the TM-2441 ABPM device and the reference sphygmomanometer was within limits allowed by the ISO standard. Bland–Altman plots of the measurements and differences between the values obtained from the study device and those from the reference device showed no systematic variations in error. It was not possible to perform a stress test in most patients due to refusal or poor physical condition.

Conclusion
The TM-2441 ABPM device fulfilled all the requirements of the ISO standard for ambulatory testing not only in a general population but also in the subgroup of subjects with type 2 diabetes.
Factors Associated With Psychotherapist and Psychiatrist Participation in Public Insurance
Authors: Tadmon Daniel , Gao Yihe Nina 
Published: November 2024

Objectives:
This study aims to evaluate rates of public insurance participation among the different psychotherapist professions as well as among psychiatrists. In addition, it seeks to assess individual and contextual factors that are associated with public insurance participation.

Background:
Historically, Medicaid- and Medicare-insured individuals have faced unique barriers to access to mental health professionals. Because prior literature has focused on psychiatrists, little is currently known of public insurance participation rates among psychotherapists—even though they constitute the bulk of the mental health workforce.

Methods:
A retrospective analysis of Medicaid and Medicare participation among a census of all Georgia psychologists, licensed clinical social workers, licensed professional counselors, marriage and family therapists, as well as psychiatrists, using their complete licensing rosters as of November 2023 (N = 21,260).

Results:
Findings show that 82.7% of psychotherapists did not accept any public insurance. This rate was 58.8% among psychiatrists. Among Georgia-licensed clinicians located outside of the state, likely to practice through telehealth, insurance acceptance was substantially lower than their in-state peers', suggesting that telehealth may have limited reach among publicly-insured patients. Psychotherapists’ different professions, as well as factors such as urbanicity, hospital setting, practice size, and individual tenure length, were strongly associated with the likelihood of insurance participation.

Conclusion:
Psychotherapists’ low rates of participation in public insurance programs and meaningful variation between professions underscore that policies to better Medicaid and Medicare beneficiaries’ access to mental health treatment must consider psychotherapists’ unique practice patterns and implement interventions informed by them.
Quebec Health-Related Quality-of-Life Population Norms Using the Health Utilities Index Mark 3
Authors: Poder Thomas G. , Dohouin Irène ,   on Behalf of the TORSADE Cohort Working Group
Published: November 2024

Objectives:
To provide population utility norms from the Health Utilities Index Mark 3 (HUI3) for the province of Quebec, Canada.

Methods:
This study used data from the Care Trajectories Enriched Data (TorSaDE) cohort, which combines data from the Canadian Community Health Survey (CCHS) and the Quebec Provincial Insurance Board [Régie de l’assurance maladie du Quebec (RAMQ)]. The CCHS is a multiround health-related survey conducted by Statistics Canada since 2007. For each round spanning over 2 years, respondents were randomly selected and completed an online questionnaire. Quebec data for the HUI3 were available in the CCHS for rounds 2007, 2009, and 2013. The RAMQ database is an administrative database that contains information on health care services use and medical diagnostics. HUI3 scores were stratified by sociodemographic variables, as well as by self-reported health problems in the CCHS and by medical diagnostics from the RAMQ. Medical diagnostics were retrieved for the CCHS completion year and the year before and identifiable with the ICD-9 code in the RAMQ database.

Results:
A total of 55,656 individuals were considered in this analysis. The mean (95% CI) and the median interquartile range of HUI3 were respectively 0.919 (0.918–0.919) and 0.973 (0.905–1) for the entire population. Individuals with lower scores were females, those aged 75 and over, divorced or widowed, unemployed during the last 12 months, less educated, or with a lower annual household income. Individuals born abroad and with normal weight of body mass index had higher utility scores. HUI3 score decreased with the number of diagnosed diseases from 0.946 (0.946–0946) for individuals without diagnosed disease to 0.682 (0.678–0.686) for individuals diagnosed with up to 18 diseases. Regardless of the number of diagnosed diseases in the RAMQ database, individuals who self-reported suffering from a single health problem presented a significantly lower HUI3 ranging from 0.944 (0.943–0.944) for Asthma to 0.789 (0.782–0.796) for Alzheimer compared with 0.956 (0.956–0.957) for individuals with no reported health problems. The same pattern was observed when considering individuals regardless of the diagnosed and self-reported diseases.

Conclusion:
Utility score norms for HUI3 were produced in the general population of Quebec. Significant differences among various health problems were identified and norms can be used to compare populations in studies that do not have a control group.