bluuebunny/crossref_metadata_2025_split huggingface dataset:
ÖĞRETMEN ADAYLARININ DİJİTAL YETERLİKLERİNİN GELİŞTİRİLMESİNE YÖNELİK BİR EĞİTİM ETKİNLİĞİ: BÖTE VE DİĞER BRANŞLARDAKİ ÖĞRETMEN ADAYLARININ GÖRÜŞLERİ
Authors: ÇEBİ Ayça , REİSOĞLU İlknur 
Published: August 2019

Bu çalışmada, DigComp çerçevesi temel alınarak, öğretmen adaylarının dijital yeterliklerini geliştirmeye ve desteklemeye yönelik bir eğitim etkinliği tasarlanmıştır. Çalışmanın amacı, verilen dijital yeterlik eğitiminin öğretmen adaylarının eğitimden önceki bilgi ve becerilerinde değişim meydana getirip getirmediği belirlemek; Bilgisayar ve Öğretim Teknolojileri Eğitimi (BÖTE) ve diğer branşlardaki öğretmen adaylarında eğitim öncesi ve eğitim sonrası durumlarının karşılaştırmaktır. Bu bağlamda, Türkiye’nin 28 farklı üniversitelerinden 30 öğretmen adayına, 6 gün boyunca toplam 51 saat, “bilgi ve veri okuryazarlığı”, “iletişim ve işbirliği”, “dijital içerik oluşturma”, “güvenlik” ve “problem çözme” konularında dijital yeterlik eğitimi verilmiştir. Eğitimin öncesinde ve sonrasında öğretmen adaylarının dijital yeterliklerine ilişkin görüşlerini belirlemek amacıyla araştırmacılar tarafından geliştirilen 33 maddelik bir anket kullanılmıştır. Elde edilen veriler non-parametrik testler ile analiz edilmiştir. Çalışmanın sonucunda gerek BÖTE gerekse de diğer branşlardaki öğretmen adaylarının “bilgi ve veri okuryazarlığı”, “iletişim ve işbirliği”, “dijital içerik oluşturma”, “güvenlik” ve “problem çözme” alanlarıyla ilgili gelişim gösterdiği sonucuna ulaşılmıştır. Ayrıca BÖTE ve diğer öğretmen adaylarının eğitim öncesi ve eğitim sonrası durumları karşılaştırıldığında, eğitim öncesinde “bilgi ve veri okuryazarlığı” hariç diğer tüm alanlarda BÖTE öğretmen adayları lehine anlamlı farklar elde edilirken, eğitim sonunda BÖTE öğretmen adayları ve diğer branşlardaki öğretmen adayları arasında dijital yeterliklerine ilişkin birçok görüşte farkın olmadığı tespit edilmiştir. Gerçekleştirilen çalışmanın geleceğin okullarında görev yapacak öğretmen adaylarının dijital yeterlik alanlarındaki eksikliklerin belirlenmesi ve verilecek dijital yeterlik eğitimlerinde hangi konulara odaklanılması gerektiğine ilişkin alanyazına katkı sağlayacağı düşünülmektedir.
Richard Ernst: Diccionario de la Técnica Industrial. Tomo VI: español-alemán. 3.ª edición enteramente refundida y muy aumentada por Rudolf Kostler. Coautor: Wolfgang Gleich.
Authors: Aramayo Perla Julio 
Published: August 2019

Reseña de libro: Richard Ernst: Diccionario de la Técnica Industrial. Tomo VI: español-alemán. 3.ª edición enteramente refundida y muy aumentada por Rudolf Kostler. Coautor: Wolfgang Gleich. [Warterbuch der industriellen Technik. Bd. VI: Spanisch- Deutsch. Dritte, vollkommen überarbeitete und erweiterte Auflage von RudolfKostler. Mitverfasser: Wolfgang Gleich]. Wiesbaden, Oscar Brandstetter Verlag, 2000.
Estudio de costo-efectividad en hipertensión arterial pulmonar Grupo 1: riociguat y sildenafil
Authors: Barajas Tarazona Jhoan , Linares Leguizamón Jessica 
Published: August 2019

Introducción. En los últimos años se han desarrollado nuevas terapias para el tratamiento de la hipertensión arterial pulmonar (HAP); sin embargo, la adopción de estas conlleva un aumento considerable de los costos por parte de las entidades promotoras de salud.
Objetivo. Evaluar la costo-efectividad de riociguat versus sildenafil en monoterapia para pacientes con diagnóstico de HAP del Grupo 1 en las clases funcionales II y III.
Materiales y métodos. Se diseñó un modelo de Márkov donde todos los individuos inician en clase funcional II con alguna de las dos terapias evaluadas en monoterapia y tienen como desenlaces principales la progresión a la clase funcional IV y la muerte. Se realizó un análisis probabilístico y determinístico de sensibilidad.
Resultados. Se encontró una relación de costo-efectividad de riociguat frente a sildenafil de $529.213.933; sin embargo, en el umbral de aceptabilidad para Colombia este no es costo-efectivo.
Conclusión. Se aconseja la implementación de sildenafil como medicamento de primera línea.
Infección por Listeria monocytogenes en una mujer gestante con lupus eritematoso sistémico y síndrome HELLP
Authors: Appel Tobias Manuel , Castellanos Daniela , Uriel Montserrat , Romero Ximena 
Published: August 2019

La listeriosis es una enfermedad transmitida principalmente por alimentos contaminados con Listeria monocytogenes. Se presenta con mayor frecuencia en neonatos, mayores de 65 años, mujeres gestantes y pacientes inmunosuprimidos. La infección por L. monocytogenes durante la gestación se asocia a una importante morbimortalidad materno-fetal.
Se reporta el caso de una mujer gestante de 29 años de edad con lupus eritematoso sistémico, a quien se le diagnosticó bacteriemia por L. monocytogenes. Durante la hospitalización, el cuadro clínico se complicó con hipertransaminasemia y, ante la presencia de trombocitopenia, se estableció el diagnóstico presuntivo de síndrome HELLP. El alto riesgo de morbimortalidad llevó a una finalización precoz dela gestación.
La importancia de este trabajo clínico radica en presentar la dificultad en el diagnóstico y manejo en una paciente gestante de gran complejidad con una infección relativamente frecuente que puede pasar desapercibida.
Media Pembelajaran dalam Pandangan Islam
Authors: Zainuri Ahmad 
Published: August 2019

With the upgrading of scientific and technological developments, it is the driving force in the utilization of technology in improving the quality of learning. With the mastery of cutting-edge technology, making the media of learning in the view of Islam, as a tool to reveal more deeply in the deepening of the material that exists in the Qur'an, because after all the existing content in the Qur'an no word runs out, the more excavated will be the wider coverage of comprehensive Qur'anic recitation. Thus, the existence of the media is as a tool to explore the sciences contained in al-quran, as has been taught by the Prophet Muhammad to his companions in conveying a good message concerning the truth or kebathilan, so that people will think what to do and which should be shunned as a prohibition, so that the learning media in Islamic view is very wide to be studied further.
Dengan pemutakhirnya perkembangan ilmu pengetahuan dan teknologi menjadikan pendorong dalam pemanfaatan teknologi dalam dalam peningkatan kualitas pembelajaran. Dengan penguasaan teknologi yang mutakhir, menjadikan media pembelajaran dalam pandangan Islam, sebagai alat untuk menguak lebih dalam dalam pendalaman materi yang ada dalam al-Qur’an, karena bagaimanapun kandungan yang ada dalam al-Qur’an tidak ada kata habis, semakin digali akan semakin luas cakupan pembahaal a-Qur’an secara komprehensif. Dengan demikian, keberadaan media adalah sebagai alat bantu untuk mendalami ilmu-ilmu yang terkandung dalam al-qur’an, sebagaimana telah diajarkan oleh Nabi Muhammad kepada para sahabatnya dalam menyampaikan risalah baik yang menyangkut kebenaran ataupun kebathilan, sehingga manusia akan berpikir mana yang harus dilakukan dan mana yang harus dijauhi sebagai larangan, sehingga media pembelajaran dalam pandangan Islam sangat luas untuk dikaji lebih lanjut.
Biodiversity in the Lakes Region (Türkiye) and its Agricultural Importance
Authors: Özçelik Hasan 
Published: August 2019

Flora of Lakes region has not been fully worked out. Especially
Burdur and Denizli have not been fully reflected in the literature since they
have been studied less than our other vilayets. According to the results of the
study; 406 (27%) in Isparta; 370 (22 %) in Burdur; 400 (18 %) in Denizli; 429
(29%) in Konya and 468 (32%) in Antalya were understood to be natural
distribution of endemic plant taxa. The number of endemic plant taxa belonging
to 53 families is 950. 530 taxa of them spread show in the region more than
one. It is estimated that for each province will be added at least 15% more
endemic taxa to this number.

Vertical distributions of the endemic taxa: 78 taxa
(8%) between 0-500 m; 31 taxa (3%) between 500-1000 m; 91 taxa (10%) between
1000-1500 m; 59 taxa (6%) between 1500-2000 m; 29 taxa (3%) between 2000 and
2500 m; 10 taxa (1%) with 2500 m upper and 645 taxa (69%) with variable
altitudes.

Flowering months of taxa: 1-3: 5 taxa (1%); 3-6: 333 taxa
(36%); 6-9: 516 taxa (55%); 9-12: 12 taxa (2%) and unknown 44 taxa (5%).
Gymnosperms (open seeded) and ferns were identified as 4 taxa (1 %).

The IUCN threat categories of the relevant taxa are: LR
(cd) 127 taxa (13%); LR (nt) 78 taxa (8%); LR (lc) 288 taxa (30%); VU 176 taxa
(19%); CR 41 taxa (4%); DD 16 taxa (2%); EN 168 taxa (18%) and 56
non-endangered taxa (6%).

Local endemics that have economic importance in the region are Origanum
minutiflorum, Sideritis erythrantha, Ballota cristata, Dorystoechas hastata,
Rosa dumalis subsp. boissieri var. antalyensis, Muscari bourgaei,
Orchis anatolica, Liquidambar orientalis, Abies cilicica subsp. isaurica.
Attention should be paid to the protection-using balance of these taxa.
Sectoral stakeholders should be made more conscious. It should be sought the
way to receive culture the taxa.

Approximately
120 vascular plants of the Lakes Region are candidate to be the industrial
purposing. These important plants in the region are as follows; Poppy (Papaver
somniferum), Caper (Capparis spp.), Centaury (Hypericum
spp.), Rose/ rosehip (Rosa damascena, R. canina, R. dumalis, R.
alba, R. semperflorens, R. versicolor, R. borboniana, R. centifolia, R. gallica),
Lavander (Lavandula stoechas, L. angustifolia and L.
intermedia), Sütçüler oregano (Origanum minutiflorum), Dedegül tea/
Kafaotu (Cyclotrichum origanifolium), Special-mint (Calamintha nepeta),
Melissa / Lemon balm (Melissa officinalis), Baby's-breath(Gypsophila
arrostii var. nebulosa), Sahleb (Orchis,
Ophyris and Dactylorrhiza spp.) Blackberry (Rubus spp.), Terebinth (Pistacia
terebinthus), Carnation (Dianthus spp.), Coriander (Coriandrum
sativum), Hibiscus (Alcea and Althaea spp.), Fennel (Foeniculum
vulgare), Love-in-a-mist (Nigella sativa, N. damascena), Dill
(Anethum
graveolens), Mint (Mentha spp.), Rosemary (Rosmarinus
officinalis), Thyme (Thymus, Origanum, Corydothymus
etc.) Linden (Tilia spp.), Poplar (Populus
spp.), Willow (Salix spp.), Fıstıkçamı/ Pine (Pinus pinea), Pumpkin/
Gourd (Cucurbita, Laganeria and Luffa spp.) etc.
Influence of landscape structure on the abundance of Desmodus rotundus (Geoffroy 1810) in northeastern Yucatan, Mexico
Authors: Bolívar-Cimé Beatriz , Flores-Peredo Rafael , García-Ortíz Scarlett Aislinn , Murrieta-Galindo Rene , Laborde Javier 
Published: August 2019

Although the transformation of landscapes by human activity can negatively affect the populations of several bat species, other species may benefit from these transformations. One of such species is the vampire bat, Desmodus rotundus, which can often be found in landscapes dominated by livestock activities. Furthermore, there are certain structural landscape characteristics that could be positively influencing the abundance of the vampire bat. To assess this possibility, eight sampling sites in northeastern Yucatan, Mexico were monitored from June 2010 to February 2012. Four sites were located in forest fragments amongst a highly fragmented landscape dominated by pastures dedicated to livestock activities, and four sites were located within continuous tropical semideciduous forest with almost no fragmentation. Forest fragmentation was characterized around the sampling sites within a 2.5 km radius using SPOT images from 2010, and five landscape variables were calculated using FRAGSTATS. The results showed that landscape heterogeneity and an agricultural aggregation index both had a significant effect on the abundance of the vampire bat. Our results showed that D. rotundusabundance in northeastern Yucatan, Mexico was favored by extensive pastures as well as by landscape characteristics associated with intense forest fragmentation. However, the presence of some remnants of forest cover probably enhance the movements and persistence of this species. To reduce the negative impact of the vampire bat presence in these areas dedicated to livestock ranching activities, effective preventive vaccination campaigns could be an important strategy.
Curva de rendimiento y composición de leche en ovejas criollas de la Montaña de Guerrero, México
Authors: Nava García Alejandro , Martínez Rojero Rubén Darío , Mastache Lagunas Ángel Agustín , Ulloa-Arvizu Raúl 
Published: August 2019

El objetivo fue estimar la curva de producción de leche y determinar sus componentes químicos en ovejas Criollas Obispo. Se procesaron datos de producción de 22 ovejas con el modelo de Wood; los registros se realizaron cada semana con el método de amamantamiento-pesaje de la cría-ordeño y la determinación de la composición química se hizo con un equipo Lactichek. El pico máximo promedio de producción (539.60 g) se alcanzó en la segunda semana, con un rendimiento diario de 342.82 ± 11.59 g y producción acumulada por oveja estimada para una lactancia de 12 semanas de 30.58 ± 1.21 kg. Los promedios para proteína, grasa, lactosa, sólidos totales y sólidos no grasos fueron de 5.71%, 2.49%, 4.59%, 13.66% y 11.24%, respectivamente. La curva de producción de leche en ovejas Obispo registra su máximo incremento entre la segunda y la tercera semana posparto.
Inhibitory Activity of Levofloxacin against MDR Staphylococcus aureus and Pseudomonas aeruginosa Clinical Isolates
Authors: Nathalie Lisa , Alimsardjono Lindawati , Isnaeni Isnaeni 
Published: August 2019

Introduction: Staphylococcus aureus and Pseudomonas aeruginosa are the most dangerous and important species among their genus. These bacteria are often resistant to many classes of antimicrobial agents; which make difficulties in selecting appropriate drug to treat infections. Multidrug-resistance occurs readily in hospitals for which antimicrobials agents were used widely. Objective: The aims of this study was to determine minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) of levofloxacin against 22 multidrug resistant- clinical (MDR) strains of Staphylococcus aureus and Pseudomonas aeruginosa isolated from patients pus and urine in hospital. Methods: Determination of the MIC was performed by macro-dilution broth assay as recommended by Clinical and Laboratory Standards Institute (CLSI), while the MBC was determined one-step further after the MIC determination. Results: It was found that MIC of the levofloxacin were (0.3 ± 0.0) - >0.5 µg/mL and (0.2 ± 0.1) - (1.0 ±0.0)µg/mL against S. aureus from pus and urine, respectively. In addition, higher MICs were yielded against P. aeruginosa, (1.0 ± 0.0) - >8.0 µg/mL and (0.7 ± 0.3) - (3.0 ± 1.2) µg/mL for pus and urine isolates respectively. Similar to MICs, the MBCs against P. aeruginosa were higher than S. aureus, (0.6 ± 0.0) - > 4.0 µg/mL and (0.3 ± 0.0) - >8.0 µg/mL isolated from pus and urine respectively, (2.0 ± 0.6) - > 8.0 µg/mL and (3.0 ± 1.2) - >7.0 µg/mL against P. aeruginosa from pus and urine respectively. Conclusion: The levofloxacin was still susceptible as bacteriostatic against isolates from both body fluids, but not bactericidal towards all isolates.
Using Project-Based Learning in Improving Students' Critical Thinking Skills to Separate of Mixtures
Authors: Insani Nurul , Fadiawati Noor , Rudibyani Ratu Betta , Fauzi Syamsuri M. Mahfudz 
Published: August 2019

Nowadays the development of thinking skills has become the main focus in educational research. Standard of graduate competency mandate that graduates of schools to universities in Indonesia must have thinking skills. Related to this, the goal of this quasi-experimental study was to describe the effectivity of Project-Based Learning (PjBL) student worksheets to improve students' critical thinking skills (CTS) in the topic of mixtures separation. This study was carried out in the SMPN 1 Pugung by using the Non-Equivalent (Pretest-Posttest) Control Group Design. The effectivity of PjBL student worksheets measured based on the n-gain and the effect size values. Statistically, the n-gain value of the experimental class was higher than the control class. The effect size value was in medium categorized. These results indicated that the PjBL student worksheets were effective to improve students' CTS in the topic of mixtures separation. Keywords: student worksheets, project-based learning, critical thinking skills, mixtures separation
Combined Massive Allograft and Intramedullary Vascularized Fibula as the Primary Reconstruction Method for Segmental Bone Loss in the Lower Extremity
Authors: Houben Rudolph H. , Rots Mathijs , van den Heuvel Stefanie C.M. , Winters Henri A.H. 
Published: August 2019

Background:
Reconstruction of segmental bone loss due to malignancy, infection, or trauma is a challenge for the reconstructive surgeon. The combination of a vascularized fibular flap with a cortical allograft provides a reliable reconstructive option in the lower extremity. In this systematic review, we describe the outcome of this technique for the treatment of segmental bone loss.

Methods:
A systematic review was performed on the use of a combined massive allograft and intramedullary vascularized fibula as a reconstruction method for large bone defects. We used PubMed, Embase, and the Wiley Cochrane Library.

Results:
Seventeen clinical articles were included between 1997 and 2017, reporting 329 cases of lower-extremity reconstructions. A meta-analysis was performed on primary union rates. The main outcome measures were primary union rate, complication rate, reintervention rate, and function after reconstruction. All publications showed relatively high complication (5.9% to 85.7%) and reintervention rates (10% to 91.7%) with good primary union rates (66.7% to 100%) and functional outcome (range of mean Musculoskeletal Tumor Society [MSTS] scores, 24 to 29 points).

Conclusions:
The combination of a massive allograft with intramedullary vascularized fibula provides a single-step reconstruction method for large bone defects (>6 cm) in the lower extremity, with good long-term outcomes.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Genome-Wide Exploration of Thaumatin-like Protein (TLP) Gene Family in Cereals
Authors: Iqbal Irfan , Tripathi Rajiv Kumar , Wilkins Olivia , Singh Jaswinder 
Published: August 2019

Abstract
Background:
TLP genes are the members of a conserved pathogenesis-related protein 5 (PR-5) gene family. They play role in abiotic stress response, hormone signaling, cell death, cold tolerance, enzyme inactivation, fruit maturation and seed germination. In this study, we characterized the TLP gene family in barley with specific emphasis on germination and malting.
Results: We identified 19 TLP genes from the reference genome of Hordeum vulgare L. cv. Morex and 37, 28 and 35 TLP genes from the Oryza sativa, Brachypodium distachyon and Sorghum bicolor genome respectively. Comparative phylogenetic analysis and thaumatin domain organization of TLPs using the conserved region classified the TLP family into nine groups. Data revealed that localized gene duplications contributed to the expansion of the TLP gene family in cereals with diverse exon/intron structures. In the barley genome, most HvTLPs were localized on chromosome 5H. The differential spatiotemporal expression pattern of HvTLP genes in barley indicate that TLPs have been expressed predominantly in the embryo, developing grains, root and shoot tissues. Additionally, transcript abundance of HvTLP genes was measured between 16 hrs. to 96 hrs. of grain germination. Differential expression of HvTLP14, HvTLP17 and HvTLP18 in the malting variety (Morex), as compared to the feed variety (Steptoe) at different stages of seed germination indicates their possible role in malting.
Conclusion: Barley genome contains higher number (19) of TLP genes as previously thought (8). This study provides a description of the TLP gene family in barley and their differential expression between 16-96 hrs. of germination. The results indicate their possible involvement in the malting process.
Keywords: Cereals, Barley, Thaumatin like-proteins, Phylogenetics, Expression analysis
Genome-wide identification of small heat shock protein (HSP20) genes family in grape and expression profile during berry development process
Authors: Ji Xiao-Ru , Yu Yi-He , Ni Pei-Yi , Zhang Guo-Hai , Guo Da-Long 
Published: August 2019

Abstract
Background

Studies have shown that HSP20 genes plays an important role in regulating plant growth, development and stress response. However, the grape HSP20 genes family have not been well studied.

Results

A total of 51 VvHSP20 genes were confirmed from grape genome. And they were divided into eleven subfamilies (CI, CII, CIII, CV, CVI, CVII, MI, MII, ER, CP and PX/Po) based on the phylogenetic tree and subcellular localization. Further structural analysis showed that the same group of VvHSP20 in the phylogenetic tree had the same motif and the structure was relatively conservative in the evolutionary process. In addition, majority of the VvHSP20 genes were located on the proximate or the distal ends of the chromosomes and four groups of VvHSP20 genes can be identified as tandem duplication genes, which inferred that tandem duplication played a predominant role in the expansion of VvHSP20 family together. To determine the functions of VvHSP20s during the development of grape berries, the expression profiles of VvHSP20s genes were analyzed after H2O2 treatment. VvHSP20s genes indeed involved in the grape berry development and the differences in transcription levels of VvHSP20s may be the result of functional differentiation of genes during evolution.

Conclusions

The results provide valuable information on the evolutionary relationship of the VvHSP20 family and on the functional properties of the VvHSP20 genes for grape berry development.
The Age of Natural Menopause and Related Factors among the Population of the Tabari Cohort.
Authors: Zamaniyan Marzieh , Moosazadeh Mahmood , Peyvandi Sepideh , Jaefari Kaveh , Goudarzi Reza , Moradinazar Mahdi , kheradmand motahareh 
Published: August 2019

Abstract
Background: Age of menopause is affected by several factors. In this study we aimed to identify the age of natural menopause and its related factors in a large-scaled population-based cohort study in Iran.
Methods: In this study, we utilized a subset of data collected in enrollment phase of Tabari cohort study (TCS). Reproductive history and other related data were collected using structural questionnaire. Blood samples were collected form all participants. We analyzed data using chi-square, independent t-test and ANOVA as well as multivariate linear regression model.
Results: Among all participants of Tabari cohort, 2753 were menopause women. The mean age of natural and induced menopause was 49.2±4.7 and 43.2 ± 6.4 respectively (P = 0.001). Our finding showed that number of pregnancy, breastfeeding duration, education, residency, thyroid disease and body mass index affect age of menopause. After adjustment for confounding variables, number of pregnancy remained significantly associated with late menopause.
Conclusion: Results of the present study showed that number of pregnancy was positively associated with menopausal age.