bluuebunny/crossref_metadata_2025_split huggingface dataset:
Why Does Deep Convection Have Different Sensitivities to Temperature Perturbations in the Lower versus Upper Troposphere?
Authors: Tian Yang , Kuang Zhiming 
Published: November 2018

Abstract
Previous studies have documented that deep convection responds more strongly to above-the-cloud-base temperature perturbations in the lower troposphere than to those in the upper troposphere, a behavior that is important to the dynamics of large-scale moist flows, such as convectively coupled waves. A number of factors may contribute to this differing sensitivity, including differences in buoyancy, vertical velocity, and/or liquid water content in cloud updrafts in the lower versus upper troposphere. Quantifying the contributions from these factors can help to guide the development of convective parameterization schemes. We tackle this issue by tracking Lagrangian particles embedded in cloud-resolving simulations within a linear response framework. The results show that both the differences in updraft buoyancy and vertical velocity play a significant role, with the vertical velocity being the more important, and the effect of liquid water content is only secondary compared to the other two factors. These results indicate that cloud updraft vertical velocities need to be correctly modeled in convective parameterization schemes in order to properly account for the differing convective sensitivities to temperature perturbations at different heights of the free troposphere.
Inclusive and emancipatory approaches to occupational therapy practice in substance-use contexts
Authors: Godoy-Vieira Aline , Soares Cassia Baldini , Cordeiro Luciana , Campos Célia Maria Sivalli 
Published: November 2018

Background. Occupational therapy practice is enhanced through clear understanding of its epistemological foundations. In the area of substance use, practices are strongly functionalist. Purpose. This study unearths epistemologies through analyzing practices addressing the social needs of clients with problematic substance use. Method. This study used an exploratory qualitative approach and was based on Marxist philosophies. Qualitative interviews were conducted with nine occupational therapists experienced in working with substance users. Data were analyzed through a dialectic approach to content analysis based on the Marxist theory of labour process. Findings. The occupational therapy practices were found to follow common principles: clients are agents of transformation in health processes; creativity is a strong element of practice and underlies the whole therapeutic process; and conditions of social reproduction compose the object of occupational therapy (i.e., what is transformed through occupational therapy practices). Two different approaches using these principles were uncovered according to the labour-process purposes: inclusive and emancipatory. Implications. Systematization of practices based on epistemological foundations strengthens occupational therapists’ ability to link actions to theories.
A framework for occupational enablement to facilitate social change in community practice
Authors: Janse van Rensburg Elize 
Published: November 2018

Background. Community practice in occupational therapy is becoming increasingly relevant worldwide. Moreover, a social-change approach focusing on occupational enablement is pertinent in community practice as occupational therapists endeavour to promote health, well-being, and occupational justice in communities. Purpose. Drawing on theory from the fields of community development, community engagement, and occupational enablement, and based on the findings of a previous empirical, qualitative study, a framework for occupational enablement in community practice was developed. Key Issues. This article presents the background to the development of the framework, after which the framework is introduced and discussed in terms of the composition, relevance, and application of its components. The framework details outcomes and objectives that may be targeted and activities that may be utilized successfully during occupational therapy community practice engagements. It further illuminates facilitators of enablement related to contextual factors, stakeholders, and strategies that enhance the potential for enabling community practice engagements. Implications. This framework can provide a strategic management guideline for occupational therapists and students who engage with communities in endeavours such as community development and service learning.
Understanding the Criminogenic Properties of Vacant Housing: A Mixed Methods Approach
Authors: Porter Lauren C. , De Biasi Alaina , Mitchell Susanne , Curtis Andrew , Jefferis Eric 
Published: November 2018

Objectives: Abandoned houses may attract or generate crime; however, little is known about the nature of this relationship. Our study is aimed at better understanding this link. Methods: Focusing on a high-crime neighborhood in Ohio, we use spatial video and calls for service (CFS) to examine how crime changed on streets where abandoned homes were removed. We also draw on the insights of 35 ex-offenders, police officers, and residents to examine how and why abandoned houses are connected to crime in this locale. Results: On average, streets where abandoned houses were razed accounted for a lower proportion of neighborhood crime after removal. Also, a lower proportion of total CFS from these streets related to serious crime. Our narrative data indicate that abandoned houses are opportunistic because they provide cover, unoccupied spaces, and are easy targets. Conclusions: The removal of abandoned housing was associated with positive changes in crime overall; however, our approach revealed interesting variation across streets. We surmise that the relevance of a particular abandoned house may be contingent on the larger context of that street or neighborhood. In order to understand these dynamics, future research should continue to “drill down” into micro-spaces.
Gender differences in the order of appearance of elbow ossification centres
Authors: Goodwin SJ , Irwin LJ , Irwin GJ 
Published: November 2018

Background The predictable order of appearance of elbow secondary ossification centres in children is important in interpreting elbow radiographs, most commonly in the context of trauma. The usual sequence of appearance of these ossification centres is given by the acronym CRITOL, but exceptions have been described and are recognised as normal variants. Aim To investigate the extent to which the appearance of the elbow secondary ossification centres follows a predictable sequence, and to establish the incidence of exceptions to the usual CRITOL order. Methods Two-stage retrospective review of 421 elbow radiographs in children at our centre. Results Of 64 children with two visible ossification centres, there was a 23% overall variant incidence (49 CR, 15 CI). Twenty-eight children had four visible ossification centres, with an overall variant incidence of 32% (19 CRIT, 9 CRIO). The variants were significantly more common in girls than in boys ( p < 0.001). Conclusion Whilst the majority of radiographs remained consistent with the described CRITOL sequence, variance in this order was seen in a quarter of children with two visible ossification centres, and a third of children with four visible ossification centres. Incidence of variance was much more common in girls, reaching statistical significance. Awareness of these normal variations, particularly in girls, should help to avoid misinterpretation.
Tetrandrine inhibits the proliferation and cytokine production induced by IL-22 in HaCaT cells
Authors: Wang Fang , Wang Jun , Zhang Zhuo , Chen Siwei 
Published: November 2018

Objective To investigate the effect of tetrandrine (Tet) on HaCaT cell proliferation and cytokine expression induced by interleukin (IL)-22, and to investigate the underlying mechanism. Methods The half maximal inhibitory concentration (IC50) and antiproliferation effects of Tet on IL-22-treated HaCaT cells were analysed by MTT assay. Signal transducer and activator of transcription 3 ( STAT3) expression was measured by reverse transcription plus real-time quantitative polymerase chain reaction (qPCR) and by Western blot. Phosphorylated (p)-STAT3 levels were also measured by Western blot. Cytokine production by HaCaT cells was analysed by enzyme-linked immunosorbent assay (ELISA) following administration of IL-22 and/or Tet. Results Tet displayed a dose-dependent inhibitory effect on HaCaT cell proliferation and reduced the phosphorylation level of STAT3 induced by IL-22, without affecting STAT3 mRNA and protein levels. Furthermore, co-incubation with Tet significantly down-regulated HaCaT cell production of tumour necrosis factor (TNF)-α, IL-1β, IL-6, IL-20 and chemokine (C-C motif) ligand 20 (CCL20) induced by IL-22. Conclusions Tet inhibits proliferation and cytokine production in HaCaT cells, and the process may involve the inhibition of STAT3 phosphorylation.
Contrasting Visions for Macroeconomic Theory: DSGE and OEE
Authors: Devereaux Abigail N. , Wagner Richard E. 
Published: November 2018

Dynamic stochastic general equilibrium (DSGE) modeling remains the workhorse of contemporary macroeconomics despite a growing number of critiques of its ability to explain the aggregate properties of an economic system. For the most part, those critiques accept the DSGE presumption that traditional macro data are primitive, causal data. This leads to a stipulative style of analysis where macro variables are explained in terms of one another. In contrast, we set forth an open-ended evolutionary (OEE) framework for an OEE macroeconomics. Within this framework, systems data are not primitive, but are derived from prior microlevel interactions without any presumption that those macrolevel derivations reflect systemic equilibrium among the microlevel primitive sources of action. We explore some contours of an OEE framework by placing coordination games within an ecological setting where there is no agent who has universal knowledge relevant to that ecology of games.JEL Classifications: B40, C73, D51, D85, E02
Serum Interleukin-6 Level in Children With Attention-Deficit Hyperactivity Disorder (ADHD)
Authors: Darwish Amira Hamed , Elgohary Tarek Mohamed , Nosair Nahla A. 
Published: November 2018

Introduction: Attention-deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder in children, but its specific etiology and pathophysiology are still incompletely understood. Objectives: This case-control study aimed to measure the level of serum interleukin-6 (IL-6) as a predictor of the immunologic status in children with ADHD, and to study its correlation with severity of symptoms. Subjects and Methods: 60 ADHD children who met the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, criteria for ADHD and 60 control children were subjected to complete history taking, clinical examination, and psychometric tests. Serum interleukin-6 of ADHD patients and control children was measured by enzyme-linked immunosorbent assay. Results: The mean serum level of IL-6 was 22.35 (95% confidence interval [CI], 17.68-26.99) in ADHD patients, and it was 5.44 (95% CI, 4.81-6.06) in controls. A significantly higher level of IL-6 was reported in ADHD patients compared with controls ( P = .001). No significant correlation was found between serum IL-6 level and either the Intelligence Quotient (IQ) or the Conners’ Parent Rating Scale score. Conclusion: Serum IL-6 values were significantly higher in ADHD patients compared to healthy control children. Increased production of IL-6 may play a role in the pathogenesis of ADHD.
Nursing students’ ethical challenges in the clinical settings: A mixed-methods study
Authors: Mehdipour Rabori Roghayeh , Dehghan Mahlagha , Nematollahi Monirosadat 
Published: November 2018

Background: Nursing students experience ethical conflicts and challenges during their clinical education. These may lead to moral distress and disturb the learning process. Objectives: This study aimed to explore and to evaluate the nursing students’ ethical challenges in the clinical settings in Iran. Research design: This was a mixed-methods study with an exploratory sequential design. Participants and research context: A total of 37 and 120 Iranian nursing students participated in the qualitative and quantitative phases, respectively. Ethical considerations: The ethical committee of Kerman University of Medical Sciences, Iran, approved the protocol of the study. Findings: Three main categories were extracted from qualitative data including Low attention of nurses to the patients’ preferences; Lack of authority; and Inadequate support. A total of 97% of the students had more than one ethical challenge in clinical settings and 48% of them stated that their challenges did not resolve. The total score of perceived ethical challenges was 62.03 ± 9.17, which was moderate. The highest mean score related to the “Low attention of nurses to the patients’ preferences” subscale. Discussion: The finding confirmed most of the existing results of other international researches about the frequency and kinds of baccalaureate nursing students’ ethical challenges. Conclusion: Identifying student ethical challenges helps teachers to manage their clinical learning process better. This study may provide a view for the nurses, clinical educators, and managers toward nursing students’ ethical challenges and their impact on nursing students’ clinical experiences.
Hospice Bereavement Service Delivery to Family Members and Friends With Bereavement-Related Mental Health Symptoms
Authors: Ghesquiere Angela , Bagaajav Ariunsanaa , Metzendorf Marguerite , Bookbinder Marilyn , Gardner Daniel S. 
Published: November 2018

Objectives: A sizable minority of those who lose a loved one in hospice will experience symptoms of bereavement-related mental health disorders. Though hospices offer services to bereaved informal caregivers (family members or friends) of patients, little is known about services offered or interest in them. Therefore, we sought to assess services offered by hospice staff and interest expressed by bereaved informal caregivers with symptoms of depression, anxiety, or complicated grief (CG). Methods: De-identified electronic bereavement care charts of 3561 informal caregivers who lost someone in a large urban metropolitan hospice from October 1, 2015, to June 30, 2016, were reviewed. Results: Of bereaved informal caregivers in the sample, 9.4% (n = 333) were positive for symptoms of depression, anxiety, or CG. The symptom-positive family members/friends were more likely than other family members/friends to be offered mailings, one-to-one counseling, telephone calls, and reference material. However, interest in most services by symptom-positive caregivers was low, with only 6% interested in one-to-one counseling and 7% interested in outside referral. Discussion: The findings suggest that hospices offer a range of services to family members or friends with symptoms of anxiety, depression, and CG, but that there can be a gap between what is offered and in the interest levels of the bereaved. Engagement with symptomatic family members and friends could be enhanced in future work.
Successful Advance Care Planning in a Rural Nursing Home
Authors: Hold Judith , Payne Camille , Lesandrini Jason , Glover Avery Caz 
Published: November 2018

Background: Advance care planning (ACP) often culminates in the completion of advance care directives (ACD), which is a written record of informed decisions specifying the type and extent of desired medical treatment. Documentation of ACD in nursing homes in the United States indicates a 60% to 70% completion rate. There are little data on the time at which ACD are completed in relation to when the resident was admitted to the nursing home facility. Objective: To explore the success of advanced care planning at a large, rural long-term care (LTC) facility. Methods: A descriptive approach, using a retrospective chart review, of 167 residents was used to examine resident completion of health-care system documents, legal documents, predisposing factors (resident demographics and psychosocial characteristics), and the actual process of ACP as defined by the rural LTC facility. Results: This nursing home utilizes a document entitled resident preference for life-sustaining treatment (RPLST). For residents who do not have formal prepared advance directive documents, the RPLST serves to define resident and family choices for resuscitation and implementation of fluids, nutrition, medications, and antibiotics. The most striking finding was the completion rate of the RPLST within 100 days of being admitted to the nursing home. Conclusion: Documentation of end-of-life preferences within 10 days of admission was achieved through the incorporation of RPLST during the resident admission process.
Genetic Analysis of Copy Number Variation in Large Chorangiomas
Authors: Sirotkina Meeli , Douroudis Konstantinos , Westgren Magnus , Papadogiannakis Nikos 
Published: November 2018

Introduction Chorangioma (CA) is the most common nontrophoblastic, vascular tumor-like lesion of the placenta with a reported incidence of 0.5% to 1% in all examined placentas. The underlying molecular mechanisms of CAs are still poorly elucidated, and a systematic investigation of the genetic background of CAs has not previously been done. Materials and Methods Tissue biopsies from 8 large (>40 mm) histologically confirmed CAs and 8 unaffected matched placenta controls, along with standard control DNA samples were analyzed for large genomic deletions and duplications using array comparative genomic hybridization (array-CGH) method. Results Array-CGH analysis revealed no rare or novel copy number variants in the CA samples compared with either standard control DNA or unaffected placenta DNA from the same individual. Discussion In this study, a systematic genetic investigation of 8 large CAs failed to demonstrate any large-scale pathogenic genetic changes. This lack of association might support a nongenetic, nontumorous origin of these lesions; however, additional genetic studies focusing on smaller genomic alterations are required to fully assess any possible genetic contribution.
Efficacy of ultra-low-dose (0.1 mg) ranibizumab intravitreal injection for treatment of prethreshold type 1 retinopathy of prematurity: A case series
Authors: Ahmed Islam SH , Hadi Ahmed MA , Hassan Hassan H 
Published: November 2018

Aim: To report the results of treatment of type 1 prethreshold retinopathy of prematurity using intravitreal injection of ultra-low dose of ranibizumab (0.1 mg in 0.01 mL). Design: A retrospective observational case series study. Methods: Review of files of eligible infants who received this form of treatment to determine the outcome of treatment and any associated ocular or systemic side effects. Results: The study included 24 eyes of 12 preterm infants with mean gestational age of 29.75 ± 1.54 weeks and mean birth weight of 1074.58 ± 320.59 g. A total of 22 eyes (91.67%) had zone II disease while 2 eyes of one infant (8.33%) had zone I disease. All cases showed regression of the signs of the active retinopathy of prematurity with complete retinal vascularization. None of the cases required retreatment. Three eyes developed ocular complications. Apart from mild feeding intolerance that lasted for 24 h after injection in one infant, none of the cases developed systemic side effects. Conclusion: Intravitreal injection of ultra-low-dose ranibizumab showed promising efficacy and good ocular safety. However, further large-scale studies are required to give stronger evidence about the efficacy and safety of ultra-low-dose ranibizumab.
The Assessment of Cross Machine Openness Uniformity of a Fiber Feed Matt
Authors: Oumera Ayad , Seyam Abdelfattah M. , Oxenham William 
Published: November 2018

The one-dimensional characteristic of yarn has resulted in very little attention being given to the uniformity of carded web in the cross machine direction. The development of nonwovens has prompted researchers to reconsider the importance of cross machine uniformity in determining the total uniformity of the carded web. It is therefore important to develop manual and online techniques to quantify cross machine uniformity at both the input and output of the card. At the card input, uniformity is taken as representing both mass and openness characteristics of the feed matt. While at the card output, there are many available techniques that allow the on-line measurement of the mass uniformity of the carded web, determination of uniformity at the input level is more difficult. The approach that was taken was to use an off-line technique to find the mass and openness of the feed matt at different locations across the card. While traditionally mass as a property has been given a lot of importance, much less attention has been given to the concept of openness. This is due in part to the difficulty in quantifying openness. Openness is believed to have great significance in determining the overall quality of the carded web, especially with regard to the formation of neps. In order to make the concept of openness more clear, it was found necessary to develop a way of quantifying it. This was done by performing a compression test on the feed matt, and then fitting the compression data with an exponential curve. The coefficient of the exponent was used to represent openness. This approach was used to find the effect of the feed roller (pin type) on cross machine uniformity. It was found that the squeezing of the feed roller did not have an effect in redistributing the mass of the feed matt, but did have an effect in changing the openness of the feed matt. Because of the difficulty involved in the handling of the feed matt, a newly developed technique is suggested to characterize openness. While this method still relies on the compression characteristics of the feed matt, it is more appropriate because it is performed on-line. Preliminary results are reported. It was found that thickness measurement under carefully selected pressure value could be used to characterize openness precisely.