bluuebunny/crossref_metadata_2025_split huggingface dataset:
Automation of the I-PASS Tool to Improve Transitions of Care
Authors: Skaret Michael M. , Weaver Travis D. , Humes Ross J. , Carbone Thomas V. , Grasso Ian A. , Kumar Harjinder 
Published: September 2019

ABSTRACT

Introduction:
Errors in communication during handoffs are a significant source of medical error and put patients at risk. The I-PASS system was designed to systematically communicate information to the oncoming healthcare provider and has been shown to decrease the risk of communication errors. The objective of this observational quality improvement study was to determine whether the addition of a partially automated, electronic handoff tool would further decrease errors in communication during transitions of care for inpatient medical teams.

Methods:
We created an electronic tool to incorporate user-generated patient information in the I-PASS format with automatically compiled data derived from the electronic medical record. Numbers of errors in the printed handoff document were recorded before and after intervention.

Results:
The first implementation cycle demonstrated an absolute risk reduction for written errors of 45.6% (95% confidence interval [CI] 39.2–51.2%) and a number needed to treat (NNT) of three patients. The second cycle showed an absolute risk reduction of 53.3% (95% CI 39.8–63.9%; NNT 2). Aggregate data showed an absolute risk reduction of 46.6% (95% CI 41.0–51.7%, NNT 3).

Conclusions:
Improving the routine task of patient handoff through the thoughtful application of technology can yield benefits in terms of decreasing documentation errors and streamlining workflow before patient handoff.
Can molecular markers of oxygen homeostasis and the measurement of tissue oxygen be leveraged to optimize red blood cell transfusions?
Authors: Baek Jin Hyen , Buehler Paul W. 
Published: September 2019

Purpose of reviewThe clinical indication for transfusing red blood cells (RBCs) is to restore or maintain adequate oxygenation of respiring tissue. Oxygen (O2) transport, delivery, and utilization following transfusion are impacted by perfusion, hemoglobin (Hb) allosteric saturation/desaturation, and the concentration of tissue O2. Bioavailable O2maintains tissue utilization and homeostasis; therefore, measuring imbalances in supply and demand could be valuable to assessing blood quality and transfusion effectiveness. O2homeostasis is critically intertwined with erythropoietic response in blood loss and anemia and the hormones that modulate iron mobilization and RBC production (e.g., erythropoietin, erythroferrone, and hepcidin) are intriguing markers for the monitoring of transfusion effectiveness in acute and chronic settings. The evaluation of RBC donor unit quality and the determination of RBC transfusion needs are emerging areas for biomarker development and minimally invasive O2measurements.Recent findingsNovel methods for assessing circulatory and tissue compartment biomarkers of transfusion effectiveness are suggested. In addition, monitoring of tissue oxygenation by indirect and direct measurements of O2is available and applied in experimental settings.SummaryHerein, we discuss tissue O2homeostasis, related aspects of erythropoiesis, molecular markers and measurements of tissue oxygenation, all aimed at optimizing transfusion and assessing blood quality.
Allogenic hematopoietic stem cell transplantation in sickle cell disease
Authors: Galal Ahmed , Asslan Mona 
Published: September 2019

Purpose of review
Discussing the currently available HSCT options for Hb SS patients highlighting advantages and disadvantages of each modality in the light of recently published data.

Recent findings
When MSD is available, myeloablative regimen is the preferred approach for otherwise healthy children whereas the nonmyeloablative (NMA) regimen is of choice for adults as well as children with SCD-associated morbidities. Mixed chimerism is common especially with NMA conditioning and is usually enough for cure. Alternative donor HSCT outcomes are progressively improving especially with posttransplant cyclophosphamide for GVHD prophylaxis.

Summary
Recent studies comparing HSCT and chronic transfusion in Hb SS patients increasingly come in favor of HSCT arm. Advances in HSCT field led to donor pool expansion and better tolerated regimens. It is easier now to tailor a personalized transplantation plan for almost every patient. A successful management plan should be sufficiently comprehensive addressing patients’ and families’ social and psychological concerns to ensure compliance and improve outcome.
Advances in aeroallergen immunotherapy
Authors: Chan Sanny K. 
Published: September 2019

Purpose of reviewAllergic rhinoconjunctivitis is the most common manifestation of allergic disease. This break in the normal natural function of the immune system to ignore harmless molecules such as pollen and pet dander to now aggressively react has lead to a substantial disease burden that is not always recognized and adequately treated.Recent findingsIndividual molecular component testing may increase the predictive value of blood sIgE and clinical symptoms. Defining the most symptoms inducing allergenic protein has led to advances in peptide-based allergen immunotherapy. There have been steady consistent reports that allergy immunotherapy for children with symptomatic allergic rhinitis prevents the onset of asthma.SummaryAllergy immunotherapy is an effective disease-modulating treatment that alters the underlying immune dysfunction which is a currently underutilized therapy especially as it is likely effective in preventing the onset of asthma in children, at least in the short term.
Recent advances in our understanding of neurodevelopmental outcomes in congenital heart disease
Authors: White Brian R. , Rogers Lindsay S. , Kirschen Matthew P. 
Published: September 2019

Purpose of review
Patients with congenital heart disease (CHD) suffer from a pattern of neurodevelopmental abnormalities including deficits in language and executive function. In this review, we summarize recent studies that examine these outcomes, their risk factors, possible biomarkers, and attempts to develop therapeutic interventions.

Recent findings
The latest literature has highlighted the role of genetics in determining neurologic prognosis, as we have increased our understanding of potentially modifiable perioperative risk factors. The role of potentially neurotoxic medical therapies has become more salient. One recent focus has been how neurodevelopment affects quality of life and leads to a high prevalence of mental illness. Neuroimaging advances have provided new insights into the pathogenesis of deficits.

Summary
Although many risk factors in CHD are not modifiable, there is promise for interventions to improve neurodevelopmental outcomes in patients with CHD. Biomarkers are needed to better understand the timing and prognosis of injury and to direct therapy. Research into psychosocial interventions is urgently needed to benefit the many survivors with CHD.
Resistance and Tolerance to Root Herbivory in Maize were Mediated by Domestication, Spread, and Breeding
Authors: Fontes-Puebla Ana A. , Bernal Julio S. 
Published: September 2019

AbstractPlants may defend against herbivory and disease through various means. Plant defensive strategies against herbivores include resistance and tolerance, which may have metabolic costs that affect plant growth and reproduction. Thus, expression of these strategies may be mediated by a variety of factors, such as resource availability, herbivory pressure, and plant genetic variation, among others. Additionally, artificial selection by farmers and systematic breeding by scientists may mediate the expression of resistance and tolerance in crop plants. In this study, we tested whether maize defense against Western corn rootworm (WCR) was mediated by the crop’s domestication, spread, and modern breeding. We expected to find a trend of decreasing resistance to WCR with maize domestication, spread, and breeding, and a trend of increasing tolerance with decreasing resistance. To test our expectations, we compared resistance and tolerance among fourZeaplants spanning those processes: Balsas teosinte, Mexican landrace maize, US landrace maize, and US inbred maize. We measured performance of WCR larvae as a proxy for plant resistance, and plant growth as affected by WCR feeding as a proxy for plant tolerance. Our results showed that domestication and spread decreased maize resistance to WCR, as expected, whereas breeding increased maize resistance to WCR, contrary to expected. Our results also showed that maize resistance and tolerance to WCR are negatively correlated, as expected. We discussed our findings in relation to ecological-evolutionary hypotheses seeking to explain defense strategy evolution in the contexts of plant resistance-productivity trade-offs, plant tolerance-resistance trade-offs, and varying resource availability vis-à-vis plant physiological stress and herbivory pressure. Finally, we suggested that defense strategy evolution in maize, from domestication to the present, is predicted by those ecological-evolutionary hypotheses.
Local regulation of lipid synthesis controls ER sheet insertion into nuclear envelope holes to complete nuclear closure
Authors: Penfield Lauren , Shankar Raakhee , Szentgyörgyi Erik , Laffitte Alyssa , Mauro Michael , Audhya Anjon , Müller-Reichert Thomas , Bahmanyar Shirin 
Published: September 2019

AbstractThe nuclear permeability barrier depends on closure of holes in the nuclear envelope (NE). Here, we use meiotic C. elegans oocytes to demonstrate that local control of glycerophospholipid synthesis by CNEP-1/CTDNEP1 regulates the insertion of ER sheets into NE holes and functions independently of ESCRT-III to ensure NE closure. Deletion of CNEP-1 causes excess incorporation of ER membranes into NE holes and a defective NE permeability barrier. ESCRT-III components accumulate at the NE opening surrounding the meiotic spindle, and loss of NE adaptors for ESCRT-III exacerbates NE sealing defects in cnep-1 mutants. Limiting ER sheet production by restoring glycerophospholipid synthesis in cnep-1 mutants rescued NE permeability defects. 3D analysis showed that membrane sheets feed into and narrow NE holes occluded by meiotic spindle microtubules supporting a role for ER sheet insertion in NE closure. Thus, feeding of ER sheets into NE holes must be coordinated with production of ER sheets near the NE to promote NE closure.
Stock returns and financial performance as mediation variables in the influence of good corporate governance on corporate value
Authors: Kurniati Suhadak 
Published: September 2019

Purpose
This paper aims to examine the influence of good governance on corporate value, in which the stock returns and financial performance act as the mediator of the relationship among them.

Design/methodology/approach
This research was conducted on companies go public listed on the Indonesia Stock Exchange and was included in 2011 to 2017 LQ45 index list, with samples taking a purposive sampling approach through four criteria. Data analysis using WarpPLS with indicator approaches are formative (mutually exclusive between indicators).

Findings
The findings are as follows: good corporate governance has a significant influence on stock returns in a negative direction; good corporate governance has no significant influence on financial performance; good corporate governance has no significant influence on company value; stock returns have a significant influence on financial performance in a positive direction; financial performance has a significant influence on stock returns with a positive direction; stock returns significantly influence the value of the company in a positive direction; financial performance has a significant influence on the company value in a positive direction.

Originality/value
The novelty in this study is that the relationship between stock returns and financial performance is reciprocal, which is the relationship among variables that affect each other (back and forth causality), in which in the previous study, the relationship between variables is only one direction; besides, the previous study conducted an analysis to find out the influence of good corporate on stock returns, company value and financial performance separately, with mixed results.
Office employee satisfaction: the influence of design factors on psychological user satisfaction
Authors: Kwon Minyoung , Remøy Hilde 
Published: September 2019

Purpose
Employees’ satisfaction and productivity is one of the main interests of employers. Psychological comfort can cause dissatisfaction with their work. Thus, it is important to understand what factors contribute to employees’ satisfaction in workplaces. The purpose of this paper is to identify the weight of contribution of each design parameter on increasing psychological satisfaction.

Design/methodology/approach
The study included 579 employees in five offices in The Netherlands through an online survey. The typologies of offices vary in terms of office layouts, orientations and façade. Additionally, a parameter of desk location was included as this factor may be associated with user satisfaction. Kruskal–Wallis H test, categorical regression, and logistic regression analyses were performed to examine the impact of these design parameters on psychological user satisfaction.

Findings
The results revealed the impact of design parameters on the psychological satisfaction. The parameters of office layouts and desk locations were the significant predictor factors for the probability of satisfaction variables (e.g. privacy, concentration, communication, social contact and territoriality). The parameters for optimal satisfaction were found in cellular office, north-west oriented workstation and 4 m away from a window.

Originality/value
Psychological comfort is an inevitable aspect in user satisfaction studies. This paper, therefore, measures and predicts the relationship between design factors and employees’ satisfaction through case studies in The Netherlands. The findings help designers, architects, planners and facility managers to develop user-focussed office design principles supporting employees’ work performance.
A holistic framework with user-centred facilities performance attributes for evaluating higher education buildings
Authors: Abisuga Abiodun Olatunji , Wang Cynthia Changxin , Sunindijo Riza Yosia 
Published: September 2019

Purpose
This paper aims to identify user-centred facilities performance attributes of higher education buildings and how they can be used to evaluate individual learning spaces. These attributes are then consolidated for developing a post-occupancy evaluation (POE) framework in this context.

Design/methodology/approach
A systematic review of the literature on the POE of higher education buildings is conducted.

Findings
This study identifies 36 facility performance attributes in higher education buildings, which can be categorised into four dimensions: ambient; spatial; technology; and building support and services requirements. These facility performance attributes need to meet user requirements to achieve satisfactory feedback. It is also important to note that user requirements differ from one learning space to another; thus, it is essential to consider the characteristics of individual learning spaces.

Research limitations/implications
The proposed evaluation framework is context-based and may not be suitable to evaluate other types of buildings. It may be further extended and enhanced to meet other facility management evaluation needs.

Practical implications
The POE framework developed in this research can be used to generate facilities management analytic to inform future design and improve existing higher education facilities.

Originality/value
This research has developed a holistic POE framework tool to meet user requirements in higher education buildings.
On-campus university student housing facility services prioritisation framework
Authors: Simpeh Fredrick , Shakantu Winston 
Published: September 2019

Purpose
The purpose of this paper is to develop a prioritisation framework that can guide the provision and management of on-campus student housing facility (SHF) services of southern Ghana Universities.

Design/methodology/approach
The paper adopted a phenomenological research strategy. Data was collected by means of focus group discussions (FGDs); a total of ten FGDs were conducted. Observations were also done during the site visit to augment the FGDs. The data were analysed thematically.

Findings
The study found that some services are perceived as “extremely important” and “basic” while others are seen as “unimportant” and “indifferent”. Services including; electricity, water, security, internet, cleaning service, maintenance service, generator, ventilation (fan), health service, library service, electric socket, study furniture, refuse collection, pest control and fire extinguisher were perceived by students as “extremely important”. However, not all of these services were perceived as “basic” requirements.

Practical implications
The framework can be used as a guide by facility and hostel managers to effectively prioritise and manage the services required in a university SHF. Moreover, when designing, constructing and adapting student housing facilities, the framework can be used as a guide to ensure that all critical services are provided in the student housing facilities.

Originality/value
Although several studies have been conducted on student housing, studies that specifically focuses on the services required in a SHF and the prioritisation of such services is lacking. This study combines students’ requirements, importance levels of requirements, and classification of requirements to develop a prioritisation system for student housing services.
The gay archival impulse: the founding of the Gerber/Hart library and archives in Chicago
Authors: Bettine Aiden M. , Mattock Lindsay Kistler 
Published: September 2019

Purpose
This paper aims to provide a more comprehensive understanding of the concept of community archives, offering a critique of the community archives discourse through a historical case study focused on the origins of the Gerber/Hart LGBTQ library and archives in Chicago.

Design/methodology/approach
This study explores the archival collections of the founders of the Gerber/Hart library and archives and the librarians that have worked there as a means for understanding the origins of the archival impulse, the rationale for building the collections and the practices that shaped the collections during the first decade of the organization’s history.

Findings
The historical analysis of the Gerber/Hart library and archives situates community archives and LGBTQ collections within the broader historical context that lead to the founding of the organization and reveals deep connections to the information professions not previously considered by those studying community archives.

Originality/value
The paper offers a reconceptualization of community archives as archival projects initiated, controlled and maintained by the members of a self-defined community. The authors emphasize the role of the archival impulse or the historical origins of the collection and the necessity for full-community control, setting clear boundaries between community archives and other participatory archival models that engage the community.
OHAM analysis for dissipative viscoelastic nanofluid considering entropy generation and activation energy
Authors: Gulzar M. Mudassar , Jabeen Shagufta , Waqas Muhammad , Shehzad Sabir Ali , Hayat Tasawar , Alsaedi Ahmed 
Published: September 2019

Purpose
The purpose of this study is to scrutinize the effects of entropy generation and nonlinear mixed convection on the boundary layer flow of second grade fluid induced by stretching sheets. Heat transfer effects are accounted in view of viscous dissipation and nonlinear thermal radiation.

Design/methodology/approach
Optimal homotopic asymptotic method procedure is adopted to obtain the analytical solution of nonlinear ordinary differential equations.

Findings
It has been noticed that Hartmann and Brinkman number has reverse characteristics against entropy generation and Bejan number.

Originality/value
To the best of the authors’ knowledge, no such analysis has been reported to date.
Painlevé analysis for three integrable shallow water waves equations with time-dependent coefficients
Authors: Wazwaz Abdul-Majid 
Published: September 2019

Purpose
The purpose of this paper is concerned with investigating three integrable shallow water waves equations with time-dependent coefficients. The author obtains multiple soliton solutions and multiple complex soliton solutions for these three models.

Design/methodology/approach
The newly developed equations with time-dependent coefficients have been handled by using Hirota’s direct method. The author also uses the complex Hirota’s criteria for deriving multiple complex soliton solutions.

Findings
The developed integrable models exhibit complete integrability for any analytic time-dependent coefficients defined though compatibility conditions.

Research limitations/implications
The paper presents an efficient algorithm for handling time-dependent integrable equations with analytic time-dependent coefficients.

Practical implications
This study introduces three new integrable shallow water waves equations with time-dependent coefficients. These models represent more specific data than the related equations with constant coefficients. The author shows that integrable equations with time-dependent coefficients give real and complex soliton solutions.

Social implications
The paper presents useful algorithms for finding integrable equations with time-dependent coefficients.

Originality/value
The paper presents an original work with a variety of useful findings.
The willingness to disclose personal information
Authors: Al-Jabri Ibrahim M. , Eid Mustafa I. , Abed Amer 
Published: September 2019

Purpose
Customer privacy and security are major concerns. Online firms worldwide collect customer data for various reasons. This study aims to investigate factors that motivate and hinder a customer’s willingness to disclose personal information (WTD) to online firms on e-commerce websites.

Design/methodology/approach
Based on an extensive literature review, three sets of factors have been identified. These sets of factors are privacy concern, perceived disclosure benefits and privacy assurances. It is hypothesized that privacy concerns negatively affect the disclosure of personal information, while the perceived benefits of disclosure have positive effects. Privacy assurances would positively affect information disclosure and attenuate the negative effect of privacy concerns on the disclosure of personal information. The authors gathered data from 253 online customers in Saudi Arabia.

Findings
The results indicate that perceived disclosure benefits and privacy concerns have a significant positive and negative relationship, respectively, with WTD online. Privacy assurances had neither a direct nor a moderating effect on information disclosure.

Research limitations/implications
The findings will inform online firms about the factors that prevent or motivate customers to disclose personal information.

Originality/value
The effect of privacy concerns and benefits on personal information disclosure are not fully understood in Saudi Arabia. This study reveals more insights into the specific factors that make online customers reluctant or motivated to disclose their personal information.