bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of Cellulase Production by Aspergillus niger Isolated from Forest Soil
Authors: Akula Srilakshmi , Golla Narasimha 
Published: October 2018

Background:An impressive increase in the application of cellulases in various fields over the last few decades demands extensive research in improving its quality and large-scale production. Therefore, the current investigation focuses on factors relevant for optimal production of cellulase byAspergillus nigerisolated from forest soil.Method:Throughout this study, the fungal strainAspergillus nigerwas maintained under the submerged condition for a period of 7 days at 120 rpm rotational speed. Various physical and chemical conditions were employed in examining their influence on cellulase production by the selected fungal strain. After appropriate incubation, culture filtrates were withdrawn and checked for FPase, CMCase, and β-D-glucosidase activities.Results:The optimum pH and temperature for cellulase production were found to be 5.0 and 32°C, respectively. Among the various carbon sources tested in the present study, amendment of lactose in the medium yielded peak values of FPase (filter paperase) and CMCase (Carboxy-methyl cellulase) whereas fructose supported the higher titers of β-glucosidase. Among the nitrogen sources, profound FPase and CMCase activity were recorded when urea was used but higher β-glucosidase activity was noticed when yeast extract was added. Various natural lignocellulosic substrates like bagasse, coir, corncob, groundnut shells, litter, rice bran, rice husk, sawdust and wheat bran were tested to find out the induction of cellulase. Among the lignocelluloses, sawdust and litter served as good substrates for cellulase production byAspergillus niger.Conclusion:In gist, the outcome of this study sheds light on the cellulolytic potentiality of the fungal strainAspergillus nigerpromising in its future commercial applications which may be economically feasible.
Prevalence and Determinants of Dyslipidemia: Data from a Saudi University Clinic
Authors: Al-Hassan Yasser Taher , Fabella Eduardo L. , Estrella Edric , Aatif Mohammad 
Published: October 2018

Background:Dyslipidemia is a risk factor for cardiovascular diseases. The relationship between demographic factors and dyslipidemia in Saudi Arabia is not completely explored.Objectives:This analytic cross-sectional study was conducted to describe the lipid profile, determine the proportion and identify significant demographic determinants of dyslipidemia among patients who have undergone lipid profile analysis in a university multispecialty clinic.Methods:The results of lipid profile examination of 1,541 King Faisal University clinic patients from 1 April, 2014 to 7 March, 2016 were compiled and subjected to descriptive and analytical statistics using STATA MP version 14. Multivariable logistic regression model using Adjusted Odds Ratio (AOR) and 95% Confidence Interval (CI) was fitted to analyze the independent predictors of dyslipidemia.Results:The prevalence of hypercholesterolemia, hypertriglyceridemia, hypo-HDL-cholesterolemia, and hyper-LDL-cholesterolemia were 13.8%, 17.0%, 40.0% 12.85%, respectively. Logistic regression revealed that in comparison with those who were 20 years old and below, those who were between the age of 40-49 years were 4.5 times more likely to have hypercholesterolemia and 3.5 times more likely to have hyper-LDL-cholesterolemia. Similarly, those who were 30-39 years old were 4.3 times and 3 times more likely to have hypertriglyceridemia and hypercholesterolemia, respectively. The same stage group was 3 times more likely to develop hyper-LDL-cholesterolemia. Females were 1.4 times more like to have hypercholesterolemia; non-Saudis were nearly twice as likely to develop hypertriglyceridemia than Saudis.Conclusion:Hypo-HDL-cholesterolemia was the most prevalent form of dyslipidemia. Age, gender and nationality were significant determinants of specific types of dyslipidemia.
Mobile App Use for Insomnia Self-Management: Pilot Findings on Sleep Outcomes in Veterans (Preprint)
Authors: Reilly Erin D , Robinson Stephanie A , Petrakis Beth Ann , Kuhn Eric , Pigeon Wilfred R , Wiener Renda Soylemez , McInnes D Keith , Quigley Karen S 
Published: October 2018

BACKGROUND

Sleep disturbance is a major health concern among US veterans who have served since 2001 in a combat theater in Iraq or Afghanistan. We report subjective and objective sleep results from a pilot trial assessing self-management–guided use of a mobile app (CBT-i Coach, which is based on cognitive behavioral therapy for insomnia) as an intervention for insomnia in military veterans.

OBJECTIVE

The primary aim of this study was to evaluate changes in subjective and objective sleep outcomes from pre to postintervention.

METHODS

Subjective outcomes included the Insomnia Severity Index, the Pittsburgh Sleep Quality Inventory, and sleep-related functional status. A wearable sleep monitor (WatchPAT) measured objective sleep outcomes, including sleep efficiency, percent rapid eye movement (REM) during sleep, sleep time, and sleep apnea. A total of 38 participants were enrolled in the study, with 18 participants being withdrawn per the protocol because of moderate or severe sleep apnea and 9 others who dropped out or withdrew. Thus, 11 participants completed the full 6-week CBT-i Coach self-management intervention (ie, completers).

RESULTS

Completer results indicated significant changes in subjective sleep measures, including reduced reports of insomnia (Z=–2.68, P=.007) from pre (mean 16.63, SD 5.55) to postintervention (mean 12.82, SD 3.74), improved sleep quality (Z=–2.37, P=.02) from pre (mean 12.82, SD 4.60) to postintervention (mean 10.73, SD 3.32), and sleep-related functioning (Z=2.675, P=.007) from pre (mean 13.86, SD 3.69) to postintervention (mean 15.379, SD 2.94). Among the objective measures, unexpectedly, objective sleep time significantly decreased from pre to postintervention (χ22=7.8, P=.02). There were no significant changes in percent REM sleep or sleep efficiency.

CONCLUSIONS

These findings suggest that the CBT-i Coach app can improve subjective sleep and that incorporating objective sleep measures into future, larger clinical trials or clinical practice may yield important information, particularly by detecting previously undetected sleep apnea.

CLINICALTRIAL

ClinicalTrials.gov NCT02392000; http://clinicaltrials.gov/ct2/show/NCT02392000
Ecthyma Gangrenosum in a Newborn Causing External Otitis with Complete Facial Nerve Palsy
Authors: Gioacchini Federico Maria , Baccarani Alessio , Villari Domenico , Postacchini Valentina , Alicandri-Ciufelli Matteo 
Published: October 2018

Background: Ecthyma gangrenosum (EG) involving the external ear canal is an unusual presentation. Objective: To describe a case of EG diagnosed in a 5-day-old female who was admitted to our institute with multiple soft-tissue lesions involving the right arm, forearm, back, and perineum and with a complete facial palsy associated with ipsilateral external otitis. Results: The patient presented neonatal sepsis associated with significant leucopenia, thrombocytopenia and alteration of the coagulation profile. Microbiological analysis was performed on the purulent otorrhea and on the exudate material collected at the level of the genital lesion; both of these specimens tested positive for the presence of Pseudomonas aeruginosa. An intravenous antibiotic treatment was administered and a rapid improvement from the infection was observed. Conclusion: The rare occurrence of this presentation, combined with the potential for fatal complications from EG if not swiftly diagnosed underline the importance of this case.
Efinaconazole 10% Nail Solution
Authors: Gupta Aditya K. , Paquet Maryse 
Published: October 2018

Background: Topical therapies for onychomycosis are associated with less adverse events than systemic therapies, but poor nail penetration limits their efficacy. Consequently, an efinaconazole 10% nail solution was developed. Objective: To review the evidence supporting the usefulness of efinaconazole monotherapy in onychomycosis management. Methods: PubMed and clinicaltrials.gov databases and abstracts from the 2013 annual meeting of the American Academy of Dermatology were searched in April 2013 using the terms “efinaconazole,” “IDP-108,” and “KP-103.” Results: In vitro, efinaconazole possesses a broad antifungal activity similar or superior to that of other antifungals. Its low affinity for keratin results in good nail penetration. Efinaconazole 10% nail solution administered daily for 36 or 48 weeks to treat mild to moderate toenail onychomycosis caused by dermatophytes results in complete and mycologic cure rates of 15 to 25% and 53 to 87%, respectively. No serious skin reaction is associated with its use. Conclusion: Efinaconazole 10% nail solution is a promising new treatment for onychomycosis.
TAX AVOIDANCE (PENGHINDARAN PAJAK) OLEH WAJIB PAJAK DALAM PERSFEKTIF ISLAM
Authors: Emzaed Ali Murtado , Syaikhu Syaikhu , Soeradji Elvi , Norwili Norwili , Munib Munib , Fitria Erry 
Published: October 2018

<p class="abstract">Tax Avoidance mempunyai spektrum persoalan yang luas, salah satunya adalah transfer harga(transfer pricing). Transfer pricing merupakan salah satu cara yang dipakai oleh wajib pajak perusahaan multinasional untuk melakukan penghindaran pajak. Perilaku transfer pricing ini tidak dipandang sebagai perilaku yang melanggar norma hukum positif yang berlaku di negara kita. Padahal perilaku ini jelas-jelas telah menggerus pendapatan negara dari sektor perpajakan. Ada gap yang serius antara aras substansi yang menjadi tujuan hukum (doelmatigheid) dengan aras kepastian hukum(rechtsmatigheid). Pada aras tujuan hukum bahwa aturan perpajakan dimaksudkan untuk pengumpulan pajak, sedangkan pada aras kepastian hukum bahwa penghindaran pajak tidak dikategorikan sebagai perbuatan yang bertentangan dengan aturan perpajakan itu sendiri. Artinya penghindaran pajak bertentangan dengan tujuan hukum perpajakan. Peneliti melihat persoalan ini dari perspektif hukum Islam yang didasarkan pada pendekatan normatif argumentatif. Penelitian ini telah menemukan adanya I’tikad tidak baik dari wajib pajak dalam memenuhi kewajibanya membayar pajak.</p>
Metode Demonstrasi dan Penugasan Terhadap Kemampuan Mendeskripsikan Hubungan Antara Ciri Khusus Mahluk Hidup Terhadap Lingkungan Hidupnya pada Siswa Kelas 5
Authors: Tarjiah Indina , Adriyawati Adriyawati , Sumantri Syarif 
Published: October 2018

Penelitian tindakan ini dilakukan untuk mengetahui perbaikan pembelajaran dengan menggunakan Penelitian Tindakan Kelas (Classroom action Research) yang dilakukan dengan menggunakan alat peraga Gambar tentang mahluk hidup , alat peraga hewan dan tumbuhan seperti cicak, daun putri malu, cocor bebek yang ada dilingkungan peserta didik. Metode yang digunakan dalam penelitian ini adalah penelitian tindakan (action research) yang dikembangkan oleh Model John Elliot . Tindakan dalam penelitian ini dilakukan dalam 2 siklus . Setiap siklus terdiri dari perencanaan, tindakan, observasi, dan refleksi. subjek penelitian perbaikan pembelajaran ini adalah anak – anak SDN Karang Satria 05 Kecamatan Tambun Utara Kabupaten Bekasi. Analisis data yang digunakan pada penelitian ini dilakukan dengan cara yaitu dengan pendekatan kuantitatif dan kualitatif. Analisis kuantitatif menunjukkan adanya peningkatan kecerdasan interpersonal mulai dari pra-penelitian sampai siklus 2 yaitu sebesar 86% Berdasarkan kesepakatan peneliti bersama kolaborator keberhasilan tindakan dapat terjadi jika ada peningkatan Kemampuan Peserta Didik dalam Mendeskripsikan Hubungan antara Ciri Khusus Mahluk Hidup terhadap Lingkungan Hidupnya mencapai 71% Pada penelitian ini, peningkatan Hasil Belajar dan Kemampuan Mendeskripsikan Hubungan antara Ciri Khusus Mahluk Hidup terhadap Lingkungan Hidupnya sudah berhasil melampaui 71%. Hasil penelitian menunjukkan bahwa penerapan metode demonstrasi serta penugasan dapat meningkatkan Hasil Belajar dan Kemampuan Peserta Didik dalam Mendeskripsikan Hubungan antara Ciri Khusus Mahluk Hidup terhadap Lingkungan Hidupnya . hal ini terlihat dari perubahan sikap anak sebelum menggunakan metode demonstrasi serta penugasan.
Hablar el idioma de la libertad. Sobre la actualidad hermenéutica del pensamiento político de Fichte
Authors: Przylebski Andrzej 
Published: October 2018

RESUMENPodemos encontrar en los escritos tardíos de Fichte un giro importante desde una perspectiva individualista del Yo hacia una perspectiva comunitaria del Nosotros. Él intentó en sus Discursos a la nación alemana explicitar una relación espiritual que trabaja contra la atomatización de una sociedad dada. Elaboró para ello un interesante concepto de nación cultural. El factor constitutivo de una nación como tal es el lenguaje, y con ello: el camino del pensamiento y la experiencia de la realidad. Fue un paso adelante, no sólo hacia la famosa afirmación hegeliana acerca del progreso histórico a través de las grandes naciones, sino también hacia un giro hermenéutico en la filosofía europea. La filosofía social del Fichte tardío es una interesante mezcla de racionalismo trascendental y conciencia histórica moderna. Llevó su pensamiento a las puertas de lo que el filósofo alemán contemporáneo H. Schnadelbach ha denominado como una segunda ilustración histórico-hermenéutica.PALABRAS CLAVESLENGUAJE, CULTURA, NACIÓN, HISTORIA HERMENÉUTICA, COMUNIDAD, ATOMIZACIÓNABSTRACTWe can find in the late writings of Fichte an important turn from an individualisticperspective of I to the community perspective of We. He tried in his Reden an die deutsche Nation to explicate a spiritual relationship that works against the atomization of a given society. He elaborated thus an interesting concept of cultural nation. The constitutive factor of such a nation is language, and with it: the ways of thinking and of experiencing the reality. It was a step ahead not only towards the famous Hegel’s claim about the historical progress through the great, leading nations, but also towards a hermeneutical turn in the European philosophy. Fichte’s late social philosophy is an interesting mixture of transcendental rationalism and modern historical consciousness. He situated his thought on the threshold to something the German contemporary philosopher H. Schnadelbach called a second, historicalhermeneutical Enlightenment.KEY WORDSLANGUAGE, CULTURE, NATION, HISTORY, HERMENEUTICS, COMMUNITY, ATOMIZATION
El kantismo de Hugo Munsterberg en los orígenes de la filosofía del cine
Authors: Ruiz Moscardó Javier 
Published: October 2018

RESUMENEl presente trabajo trata de exponer el trasfondo (neo)kantiano de la filosofía del cine de Hugo Munsterberg. Nuestro autor, reputado psicólogo experimental y profesor de Harvard, elaboró en 1916 una obra que está considerada la primera manifestación sistemática de la filosofía del cine: The photoplay: a psychological study. Nos centraremos en este libro y lo pondremos en relación con otros textos de Munsterberg en los que su teoría estética aparece. Por otro lado, y sin perder de vista la intención de rescatar los aspectos kantianos de su posición, intentaremos ofrecer un contexto teórico e intelectual de las motivaciones y temáticas de nuestro autor. PALABRAS CLAVEFILOSOFÍA DEL CINE; TEORÍA DEL CINE; MUNSTERBERG; KANTISMO; ESTÉTICA; COGNITIVISMOABSTRACTThis paper aims to explain the Kantian background of Hugo Munsterberg’s philosophy of film. Our author, who was a renowned experimental psychologist and professor at Harvard, in 1916 produced a work that is considered the first systematic manifestation of film theory: The photoplay: a psychological study . We will focus on this book but also we’ll relate it to other Munsterberg’s texts in which his aesthetic theory appears. On the other hand, we will try to offer a theoretical and intellectual context in order to contextualize all his motivations and themes. KEY WORDSPHILOSOPHY OF FILM; THEORY OF FILM; MUNSTERBERG; KANTIANISM; AESTHETICS; COGNITIVISM
The routes of critical metaphysics: Valentin Kanawrow’s contribution
Authors: Enchev Christian 
Published: October 2018

ABSTRACT:The aim of the present text is to reflect on Kanawrow’s Tetralogy as an original approach to Kantian critcal metaphysics with a view to achieving the greatest clarity level of theoretical philosophising in formal and conceptual sense. Special light will be thrown here on some logical aspects of the transition from intentionality to intensionality. Transcendental synthesis is explicated toroughtly as a generative mechanism towards initially independent objectness: the virtual topos of thinking needs an emphasis on its metaphysically clarified purity. In accordance with my own approach the transition from a priori to a posteriori should be clearly explicated as a transition from intentionality to intensionality – to regional (actual) human experience which falls in the range of presumed open valences of thinking. The newly considered virtualistic phenomenon is in use in accordance with transcendentalising of actual experience. In addition, logical functionality of thinking receives a cognitive significance against our actual experience. That guarantees a variety of successful routes of transcendental schematism in its virtualistic version (transcendental phenomenology).KEYWORDSCRITICAL METAPHYSIC, VIRTUALISTIC METAPHYSICS, VIRTUAL TOPOS OF THINKING, UNLOCKING, DEVIRTUALISATION, TRANSCENDENTAL SYNTHESIS.RESUMENEl objetivo del presente texto es reflexionar sobre la tetralogía de Kanawrow como un enfoque original de la metafísica critica kantiana con el fin de alcanzar el mayor nivel de claridad de filosofar teórico en el sentido formal y conceptual. Se esclarecerán especialmente algunos aspectos lógicos de la transición de la intencionalidad hacia la intensionalidad. La síntesis trascendental se explica como un mecanismo generativo hacia la objetividad inicialmente independiente: el topos virtual de pensamiento necesita un énfasis en su pureza que es metafísicamente aclarada. De acuerdo con mi propio enfoque la transición de a priori a a posteriori debe estar claramente explicada como una transición de la intencionalidad a la intensionalidad - hacia la (real) experiencia regional humana que se encuentra en el rango de valencias abiertas presumidas del pensamiento. El considerado virtualistic phenomenon está en uso, de conformidad con transcendentalisacion de la experiencia actual. Además, la funcionalidad lógica del pensamiento recibe un significado cognitivo en contra de nuestra experiencia real. Estas consideraciones garantizan una variedad de rumbos exitosos del esquematismo trascendental en su versión virtualistica (fenomenología trascendental).PALABRAS CLAVESMETAFÍSICA CRÍTICA, METAFÍSICA VIRTUAL,TOPOS VIRTUAL DE PENSAMIENTO, DE VIRTUALIZACIÓN
Tolerancia religiosa y argumentos liberales. Comentarios a la Carta sobre la tolerancia de John Locke
Authors: Toscano Méndez Manuel 
Published: October 2018

RESUMENEn este trabajo quiero examinar la Carta sobre la tolerancia de John Locke, con el propósito de considerar los diferentes tipos de argumentos que propone para justificar la tolerancia en materia de religión y valorar su relevancia para el lector actual. Aunque la línea argumental principal de la Carta es insatisfactoria, cabe encontrar una justiicación alternativa, mucho más afin con la defensa que el liberalismo contemporáneo hace de la libertad de conciencia.PALABRAS CLAVETOLERANCIA-RELIGIÓN-LIBREALISMO-LOCKEABSTRACTIn this paper I will examine John Locke'se Letter concerning toleration, with the aim of reviewing the different arguments he adduces to justify religious toleration and of assessing their relevance for the contemporary reader. Althought the Letter's main argument is not satisfactory, it is possible to find an alternative justification, in line with the freedom of conscience defended by contemporary liberalism.KEYWORDSTOLERATION-RELIGION-LIBERALISM-LOCKE
La Tercera Generación, o algunos de los cantos de cisne del Movimiento Moderno
Authors: Capitel Antón 
Published: October 2018

Los arquitectos del año 1918, tienen concomitancias importantes, pero hay también entre ellos notables diferencias.
Utzon ejerció siempre el organicismo, en distintas versiones del mismo. Fue referencia de Zevi en el organicismo exacerbado de la Ópera de Sídney.
Sáenz de Oíza caminó desde la recuperación racionalista como “vanguardia”, hacia alguna arquitectura próxima al Team 10, y acabó en el organicismo de “Torres Blancas” y el Banco de Bilbao.
Rudolph fue personal y ecléctico. Recibió una atención extraordinaria de Zevi en relación a su obra más celebrada, la Escuela de Arquitectura de Yale.
Van Eyck, figura básica del Team 10, criticó las secuelas de los maestros del Movimiento Moderno y trató de llevar a la arquitectura a la historia, la ciudad y la antropología. Pero su brillante obra alcanzó valores más independientes.
Todos, Zevi incluido, representaron lo mejor de la arquitectura de su tiempo, aunque también el final del Movimiento Moderno y no caminos para el futuro.
Purwarupa Radar sebagai Pendeteksi Benda Diam menggunakan Ultrasonik
Authors: RENALDI LUKY , HADIYOSO SUGONDO , RAMADAN DADAN NUR 
Published: October 2018

ABSTRAKDeteksi keberadaan objek secara otomatis pada ruangan diperlukan ketika terdapat keterbatasan dalam melakukan penginderaan. Pemanfaatan sistem radar menjadi saah satu solusi untuk penginderaan objek. Pada paper ini, diimplementasikan prototipe radar menggunakan sensor ultrasonik, mikrokontroller Arduino UNO R3 dan motor servo. Sistem ini dirancang dengan tiga buah sensor ultrasonik dengan motor sebagai penggerak horizontal dan vertikal dalam sistem pemindainya. Sensor yang berjumlah tiga buah, diletakkan pada titik yang berbeda sehingga dapat membaca jarak, sudut dan ketinggian objek dari arah titik tersebut, hasil dari pengukuran objek ditampilkan pada PC melalui aplikasi pemograman GUI. Dari hasil pengujian, radar mampu mendeteksi objek antara 5 cm dari depan radar dengan jarak maksimum 30 cm dan diperoleh tingkat kesalahan pengukuran jarak dan ketinggian sebesar 1 - 2 cm sedangkan untuk sudut 1˚- 3˚.Kata kunci: Deteksi, Radar, Ultrasonik, Jarak, SudutABSTRACTAutomatic detection of objects in the room is required when there are limitations in the sensing. Utilization of radar system becomes one solution for sensing object. In this paper, we implemented a prototype radar using ultrasonic sensor, Arduino UNO R3 microcontroller and servo motor. The system is designed with three ultrasonic sensors with motors as horizontal and vertical drive in the scanning system. Three sensors are placed at different points so that they can read the distance, angle and height of the object from that point, the result of measuring the object displayed on the PC through the GUI programming application. From the test results, the radar is able to detect objects between 5 cm from the front of the radar with a maximum distance of 30 cm and obtained the error rate measurement of distance and altitude of 1 - 2 cm while for the angle of 1˚ - 3˚.Keywords: Detection, Radar, Ultrasonic, Distance, Angle