bluuebunny/crossref_metadata_2025_split huggingface dataset:
Training professionals in a recovery‐oriented methodology: a mixed method evaluation
Authors: Bitter Neis , Roeg Diana , Van Nieuwenhuizen Chijs , Van Weeghel Jaap 
Published: January 2019

BackgroundSeveral studies have reported difficulties concerning the implementation of recovery‐oriented interventions. In this study, the effect of training in the Comprehensive Approach to Rehabilitation (CARe) on daily practice was evaluated. Additionally, we aimed to acquire insight into the experiences with the implementation process involving professionals, management and trainers.MethodsFourteen teams for sheltered and supported housing in the Netherlands participated in this study. As part of a cluster‐randomised controlled trial (RCT) design, eight teams received training in the CARe methodology. Model fidelity (using the CARe fidelity audit) and professionals’ knowledge of recovery (using the Recovery Knowledge Inventory) were measured for all teams until 20 months after the start. Afterwards, an evaluation meeting with participating stakeholders was organised in which barriers and facilitators of the implementation of the CARe methodology were inventoried.ResultsTen months after the training, the intervention teams scored higher than the control teams on the fidelity subscales: ‘recovery’, ‘strengths orientation’ and ‘amount of training and coaching’. Twenty months after the training, only the effect of ‘amount of coaching and training’ remained. Additionally, ‘methodological working’ clearly differed between the groups after 20 months in favour of the intervention teams. In all teams, model fidelity was moderate at both measurements. The knowledge of recovery of the trained teams was slightly and significantly higher at 10 and 20 months after training. Although professionals were positive about recovery and strength‐oriented working, they experienced several organisational and societal barriers.ConclusionTraining in the CARe methodology improved the fidelity and knowledge of recovery among professionals. However, the differences were small, and fidelity decreased over time. More in‐depth knowledge is needed on which barriers professionals experience in practice so that tailored training and implementation strategies can be developed. Furthermore, more attention is needed for professional development and the translation of theory into practice.
The impact of monetary and tax policy on income inequality in Japan
Authors: Taghizadeh‐Hesary Farhad , Yoshino Naoyuki , Shimizu Sayoko 
Published: January 2019

AbstractThis paper assesses the effects of the most recent monetary policy behaviour of the Bank of Japan (in particular, zero interest rate policy and negative interest rate policy) and Japanese tax policy on income inequality in this country during the period of 2002Q1 to 2017Q3. The vector error correction model (VECM) that develops in this research shows that increase in money stock (m1) through Quantitative Easing (QE) and Quantitative and Qualitative Easing (QQE) policies of theBOJsignificantly increases the income inequality. On the contrary, Japanese tax policy was effective in reducing the income inequality. Variance decomposition results show that increasing of income inequality by monetary policy is larger when comparing to decreasing effects of tax policy on income inequality. Cointegration andVECMresults show that monetary policy has both short‐run and long‐run impacts but for tax policy paper could not find any significant short‐run impact on income inequality. In addition, paper found that technological progress only in long‐run can reduce the income inequality by increasing the marginal productivity of labour with positive impacts on employment and wages.
Capital flows to Asia and Latin America: Does institutional quality matter?
Authors: Arya Vandana , Banerjee Rajabrata , Cavoli Tony 
Published: January 2019

AbstractUsing a sample of 28 emerging market economies from Asia and Latin America spanning 1990–2013, we show that the marginal effect of capital flows on growth is positive and contingent on the threshold level of institutional quality (IQ). The conditional effect of capital flows holds for both the income per capita growth and total factor productivity (TFP) growth. We also determine the different threshold levels of IQ at which the marginal effect of capital flows is positive. The overall level of IQ in the Asian countries is superior to the Latin American countries and requires a lower threshold level to exert any positive effect. While the same conditional effect of IQ holds in Latin America for TFP growth, this effect is reversed in Asia. For very high levels of IQ (91st percentile), the marginal effect of capital flows on TFP growth in Asia is almost negligible. The marginal effects also vary based on the composition of capital flows in each region.
A Third-Order Model of Hip and Ankle Joints During Balance Recovery: Modeling and Parameter Estimation
Authors: González Alejandro , Cerda-Lugo Angel , Cardenas Antonio , Maya Mauro , Piovesan Davide 
Published: January 2019

Abstract
Postural stability is important in everyday life as falls can cause severe injuries. Risk of injuries is higher in the elderly whose balance is often impaired. Modeling postural stability and the parameters that govern it is important to understand the balance mechanism and allow for the development of fall prevention strategies. Several mathematical models have been proposed to represent postural stability of bipeds. These models differ on the number of degrees-of-freedom (DOF) of the skeletal structure, force generation function for the muscle models, and capability to change their behavior as a function of the task. This work proposes a nonlinear model that captures fall recovery using a hip–ankle strategy. The muscle actuation is modeled as a third-order Poynting–Thomson's (PT) mechanical system where muscles and tendons are represented as lumped parameters actuating the aforementioned joints. Both a regression technique and a Kalman Filter (KF) are used to estimate the muscle–tendon parameters of the model. With a good model, the direct estimation of these parameters would allow clinicians to improve postural stability in the elderly, monitor the deterioration of the physical condition in individuals affected by neuro-degenerative diseases, and develop rehabilitation appropriate processes.
Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank
Authors: Pilling Luke C , Tamosauskaite Jone , Jones Garan , Wood Andrew R , Jones Lindsay , Kuo Chai-Ling , Kuchel George A , Ferrucci Luigi , Melzer David 
Published: January 2019

Abstract

Objective

To compare prevalent and incident morbidity and mortality between those with the
HFE
p.C282Y genetic variant (responsible for most hereditary haemochromatosis type 1) and those with no p.C282Y mutations, in a large UK community sample of European descent.

Design
Cohort study.

Setting
22 centres across England, Scotland, and Wales in UK Biobank (2006-10).

Participants
451 243 volunteers of European descent aged 40 to 70 years, with a mean follow-up of seven years (maximum 9.4 years) through hospital inpatient diagnoses and death certification.

Main outcome measure
Odds ratios and Cox hazard ratios of disease rates between participants with and without the haemochromatosis mutations, adjusted for age, genotyping array type, and genetic principal components. The sexes were analysed separately as morbidity due to iron excess occurs later in women.

Results

Of 2890 participants homozygous for p.C282Y (0.6%, or 1 in 156), haemochromatosis was diagnosed in 21.7% (95% confidence interval 19.5% to 24.1%, 281/1294) of men and 9.8% (8.4% to 11.2%, 156/1596) of women by end of follow-up. p.C282Y homozygous men aged 40 to 70 had a higher prevalence of diagnosed haemochromatosis (odds ratio 411.1, 95% confidence interval 299.0 to 565.3, P<0.001), liver disease (4.30, 2.97 to 6.18, P<0.001), rheumatoid arthritis (2.23, 1.51 to 3.31, P<0.001), osteoarthritis (2.01, 1.71 to 2.36, P<0.001), and diabetes mellitus (1.53, 1.16 to 1.98, P=0.002), versus no p.C282Y mutations (n=175 539). During the seven year follow-up, 15.7% of homozygous men developed at least one incident associated condition versus 5.0% (P<0.001) with no p.C282Y mutations (women 10.1%
v
3.4%, P<0.001). Haemochromatosis diagnoses were more common in p.C282Y/p.H63D heterozygotes, but excess morbidity was modest.

Conclusions

In a large community sample,
HFE
p.C282Y homozygosity was associated with substantial prevalent and incident clinically diagnosed morbidity in both men and women. As p.C282Y associated iron overload is preventable and treatable if intervention starts early, these findings justify re-examination of options for expanded early case ascertainment and screening.
Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review
Authors: Mandeville Kate L , Barker Rosie , Packham Alice , Sowerby Charlotte , Yarrow Kielan , Patrick Hannah 
Published: January 2019

Abstract

Objective
To investigate the prevalence of financial interests among patient organisations contributing to health technology assessment at the National Institute for Health and Care Excellence (NICE) in England and the extent to which NICE’s disclosure policy ensures that decision making committees are aware of these interests.

Design
Policy review using accounts, annual reports, and websites of patient organisations; payments declared by pharmaceutical manufacturers on their websites and a centralised database (Disclosure UK); declarations of interests by nominated representatives of patient organisations; and responses from patient organisations.

Setting
Appraisals of medicines and treatments (technologies) for use in the English and Welsh National Health Service.

Participants
53 patient organisations contributing to 41 NICE technology appraisals published in 2015 and 2016, with 117 separate occasions that a patient organisation contributed to the appraisal of a technology.

Main outcome measures
Prevalence of specific interests (that is, funding from manufacturer(s) of a technology under appraisal or competitor products); proportion of specific interests of which NICE’s decision making committees were aware; proportion of unknown specific interests for which disclosure was not required by NICE’s policy

Results
38/53 (72%) patient organisations had accepted funding from the manufacturer(s) of a technology or a competitor product in the same year that they had contributed to the appraisal of that technology or the previous year. Specific interests were present on 92/117 (79%) occasions that patient organisations contributed to appraisals in 2015 and 2016. NICE’s decision making committees were aware of less than a quarter of specific interests (30/144; 21%). For nearly two thirds of the specific interests not known to committees (71/114; 62%), disclosure by patient organisations was not required by NICE’s policy.

Conclusions
Financial interests are highly prevalent among patient organisations contributing to health technology assessment. NICE should review its disclosure policy to ensure that decision making committees are aware of all relevant interests.
Safety and efficiency of the fifth generation Woven EndoBridge device: technical note
Authors: Mihalea Cristian , Caroff Jildaz , Pagiola Igor , Ikka Leon , Hashemi Gelareh Bani , Naderi Soheil , Chalumeau Vanessa , Ples Horia , Popa Bogdan Valeriu , Yasuda Thomas , Marenco de la Torre Joaquin Jose , Iacobucci Marta , Ozanne Augustin , Gallas Sophie , Rouchaud Aymeric , Pescariu Sorin , Moret Jacques , Spelle Laurent 
Published: January 2019

BackroundThe treatment of wide neck bifurcation aneurysms remains challenging despite the introduction of new techniques (Y stenting, waffle cone technique, or flow diverter stents). The Woven EndoBridge (WEB) device is an innovative solution for this type of cerebral aneurysm. A new WEB 17 is now available and has been designed to offer smaller sized devices to optimize navigability and delivery.MethodsBetween February 2017 and April 2018 all patients treated with the WEB 17 device in our center were retrospectively reviewed. 25 patients with 28 non-ruptured aneurysms were identified and analyzed. Three patients with two aneurysms both treated with the WEB device were identified.ResultsThe device was successfully deployed in all cases. Procedure related morbidity was 4% and mortality was 0%. In one case, a delayed postprocedural thromboembolic event occurred owing to device protrusion. Technical success, complications, angiographic outcomes, procedural data, and follow-ups are reported. The modified Rankin Scale score at discharge was 0 for 24 patients (96%). At the 3, 6, or 9 month follow-up, angiograms were taken of 21 of the 25 patients (84%) (24 of 28 aneurysms had been controlled); 3 patients (3 aneurysms) did not receive angiographic follow-up at the time of submission of this work. Complete occlusion was achieved in 22 of 24 aneurysms (91.66%), and 2 of 24 aneurysm (8.33%) showed a neck remnant.ConclusionsThe WEB 17 is safe and technically feasible, according to this retrospective single center analysis. For very small bifurcation aneurysms, the WEB 17 seems to have lower complication rates than stent assisted techniques. However, further studies are needed to evaluate the complication rate and long term efficiency.
The 100 most cited articles in the endovascular management of acute ischemic stroke
Authors: Ravindran Krishnan , Kurda Dylan , Maingard Julian , Phan Kevin , Kok Hong Kuan , Thijs Vincent , Hirsch Joshua A , Lee Michael J , Chandra Ronil V , Brooks Duncan Mark , Asadi Hamed 
Published: January 2019

Background and purposeEndovascular thrombectomy (EVT) has revolutionized the management of acute ischemic stroke. Landmark clinical trials have shown EVT to be one of the most efficacious interventions in clinical medicine over the past 5 years. A method of recognition for an article in the scientific community is to use a citation rank list, in order to identify the seminal works in the academic medical literature. The objective of this study was to characterize the 100 most highly cited articles assessing endovascular management of acute ischemic stroke.MethodsWe conducted a retrospective bibliometric analysis using the Web of Science Citation Index Expanded database for the most cited works in the endovascular management of acute ischemic stroke. Citation count was used to rank the top 100 articles, which were then analyzed for authorship, year of publication, subject, study type, level of evidence, and subject.ResultsThe mean number of citations was 245 (range 65–1726) and 394 on Google Scholar. The top 100 articles were cited an average of 43.9 times per year and published in 21 journals in the past two decades. The majority of papers (62) were classified as constituting levels 1, 2, or 3 evidence, and included 17 randomized controlled trials. Approximately two-thirds of the top 100 articles originated from the USA.ConclusionsThis study details the most cited articles in the endovascular management of acute ischemic stroke, and furthermore shows that a high proportion of level I evidence exists for this intervention.
Intel MPX Explained
Authors: Oleksenko Oleksii , Kuvaiskii Dmitrii , Bhatotia Pramod , Felber Pascal , Fetzer Christof 
Published: January 2019

Memory-safety violations are the primary cause of security and reliability issues in software systems written in unsafe languages. Given the limited adoption of decades-long research in software-based memory safety approaches, as an alternative, Intel released Memory Protection Extensions (MPX)---a hardware-assisted technique to achieve memory safety. In this work, we perform an exhaustive study of Intel MPX architecture along three dimensions: (a) performance overheads, (b) security guarantees, and (c) usability issues.
We present the first detailed root cause analysis of problems in the Intel MPX architecture through a cross-layer dissection of the entire system stack, involving the hardware, operating system, compilers, and applications. To put our findings into perspective, we also present an in-depth comparison of Intel MPX with three prominent types of software-based memory safety approaches. Lastly, based on our investigation, we propose directions for potential changes to the Intel MPX architecture to aid the design space exploration of future hardware extensions for memory safety.
A complete version of this work appears in the 2018 proceedings of the ACM on Measurement and Analysis of Computing Systems.
On the Power-of-d-choices with Least Loaded Server Selection
Authors: Hellemans Tim , Van Houdt Benny 
Published: January 2019

Motivated by distributed schedulers that combine the power-of-d-choices with late binding and systems that use replication with cancellation-on-start, we study the performance of the LL(d) policy which assigns a job to a server that currently has the least workload among d randomly selected servers in large-scale homogeneous clusters.
We consider general job size distributions and propose a partial integro-differential equation to describe the evolution of the system. This equation relies on the earlier proven ansatz for LL(d) which asserts that the workload distribution of any finite set of queues becomes independent of one another as the number of servers tends to infinity. Based on this equation we propose a fixed point iteration for the limiting workload distribution and study its convergence.
AlloX
Authors: Le Tan N. , Sun Xiao , Chowdhury Mosharaf , Liu Zhenhua 
Published: January 2019

GPUs are considered as the accelerators for CPUs. We call these applications GPU applications. Some machine learning frameworks like Tensorflow support their machine learning (ML) jobs running either on CPUs or GPUs. Nvidia claims that Titan GPU K80 12GB can speed up 5-10x on average. Although GPUs offer the advantages on performance, they are very expensive. For example, a GPU K80 roughly costs $4000 while an Intel Xeon E5 Quad cores costs $350.
The coexist of traditional CPU and GPU applications urges cloud computing operators to build hybrid CPU/GPU clusters. While the traditional applications are executed on CPUs, the GPU applications can run on either CPUs or GPUs. In the CPU/GPU clusters, how to provision the hybrid CPU/GPU clusters for CPU and GPU applications and how to allocate the resources across CPUs and GPUs?
Interchangeable resources like CPUs and GPUs are not rare in large clusters. Some network I/O cards like wireless, ethernet, infinityband with different bandwidths can also be interchangeable.
In this paper, we focus on CPU/GPU systems. We develop a tool that estimates the performance and resource for an ML job in an online manner (§2). We implement AlloX system that supports resource allocation and places applications on right resources (CPU or GPU) to maximize the use of computational resource (§3). The proposed AlloX policy achieves up to 35% progress improvement compared to default DRF [2]. We build a model that minimizes the total cost of ownership for CPU/GPU data centers (§4).
The Neural Hype and Comparisons Against Weak Baselines
Authors: Lin Jimmy 
Published: January 2019

Recently, the machine learning community paused in a moment of self-reflection. In a widelydiscussed paper at ICLR 2018, Sculley et al. [13] wrote: "We observe that the rate of empirical advancement may not have been matched by consistent increase in the level of empirical rigor across the field as a whole." Their primary complaint is the development of a "research and publication culture that emphasizes wins" (emphasis in original), which typically means "demonstrating that a new method beats previous methods on a given task or benchmark". An apt description might be "leaderboard chasing"-and for many vision and NLP tasks, this isn't a metaphor. There are literally centralized leaderboards1 that track incremental progress, down to the fifth decimal point, some persisting over years, accumulating dozens of entries.
Sculley et al. remind us that "the goal of science is not wins, but knowledge". The structure of the scientific enterprise today (pressure to publish, pace of progress, etc.) means that "winning" and "doing good science" are often not fully aligned. To wit, they cite a number of papers showing that recent advances in neural networks could very well be attributed to mundane issues like better hyperparameter optimization. Many results can't be reproduced, and some observed improvements might just be noise.
Report on the 12th Russian Summer School in Information Retrieval (RuSSIR 2018)
Authors: Mejova Yelena , Chernyak Ekaterina , Tutubalina Elena , Braslavski Pavel 
Published: January 2019

The 12th Russian Summer School in Information Retrieval (RuSSIR 2018) was held on August 27- 31 in Kazan, Russia.1 The school was co-organized by Kazan Federal University2 and the Russian Information Retrieval Evaluation Seminar (ROMIP).
Starting from 2007, the RuSSIR school series has become an internationally recognized venue [1]-[5]. Previously, RuSSIRs have taken place in Yekaterinburg, Taganrog, Petrozavodsk, Voronezh, Saint Petersburg, Yaroslavl, Kazan, Nizhny Novgorod, and Saratov. Over these years, RuSSIR courses have been taught by world-renowned researchers and industry leaders in Information Retrieval and related areas.
This year, we had a record number of around 120 participants in total (counting in students, teachers, organizers, and sponsors' representatives); there were 87 students attending RuSSIR 2018. While the majority of participants were from various Russian universities, there were also representatives from the USA, Spain, Ireland, Switzerland, the United Kingdom, Australia, the Netherlands, Estonia, China, Germany, Italy, Denmark, Austria, and Finland. School participation was free of charge due to support from the school's sponsors. In addition, 10 international students and two teachers received travel support from the BCS IRSG and ACM SIGIR.