bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermische Energiespeicher – Trends, Entwicklungen und Herausforderungen
Authors: Scheffler Franziska 
Published: July 2019

AbstractDie Verfügbarkeit leistungsfähiger thermischer Energiespeicher ist essentielle Voraussetzung für das Gelingen der Energiewende. Basierend auf dem Anteil am Gesamtenergieverbrauch stehen (1) kostengünstige, sichere und niederschwellig nutzbare Speicher für die Bereitstellung von Raumheizung und Brauchwasser im Fokus. Darüber hinaus wird (2) Hochtemperaturspeichern zur Nutzung in solarthermischen Kraftwerken und Reaktoren ein großes Potenzial zugesprochen. Aussichtsreich ist das innovative Zusammenspiel von Materialien, intelligenter Steuerung, Vernetzung über Systemgrenzen hinaus und die Kombination verschiedener Technologien.
A meta‐analysis of the relationship between VEGFR2 polymorphisms and atherosclerotic cardiovascular diseases
Authors: Wang Li , Ge Hui , Peng Longyun , Wang Bing 
Published: July 2019

AbstractBackgroundSome previous studies explored associations between vascular endothelial growth factor receptor 2 (VEGFR2) polymorphisms and atherosclerotic cardiovascular diseases (ASCVD), with conflicting findings.HypothesisWe thought that VEGFR2 polymorphisms may influence susceptibility to ASCVD. Here, we aimed to better analyze the relationship between VEGFR2 polymorphisms and ASCVD in a larger combined population by performing a meta‐analysis.MethodsWe searched Pubmed, Embase, and Web of Science for related articles. We calculated odds ratio (OR) and 95% confidence interval (CI) to estimate whether there are genetic associations between VEGFR2 polymorphisms and ASCVD.ResultsTen studies were included for this meta‐analysis (5474 cases and 8584 controls). VEGFR2 rs1870377 (dominant comparison: 0.81 (0.73‐0.89), I2 = 56%; recessive comparison: 1.40 (1.25‐1.57), I2 = 34%; allele comparison: 0.81 (0.76‐0.87), I2 = 0%), rs2071559 (dominant comparison: 0.83 (0.76‐0.91), I2 = 0%; recessive comparison: 1.22 (1.07‐1.38), I2 = 0%; allele comparison: 0.86 (0.81‐0.92), I2 = 0%) and rs2305948 (dominant comparison: 0.79 (0.72‐0.87), I2 = 25%; recessive comparison: 1.44 (1.08‐1.92), I2 = 60%; allele comparison: 0.79 (0.68‐0.92), I2 = 73%) polymorphisms were all found to be significantly associated with susceptibility to ASCVD in general population. Subgroup analyses by type of disease revealed similar significant findings for rs1870377, rs2071559, and rs2305948 polymorphisms in coronary artery disease (CAD) subgroup. Besides, positive results were also found for rs1870377 polymorphism in ischemic stroke (IS) subgroup.ConclusionsIn summary, this meta‐analysis proved that these VEGFR2 polymorphisms could be used to identify individual with elevated susceptibility to ASCVD.
Garden balsam optimization algorithm
Authors: Li Shengpu , Sun Yize 
Published: July 2019

SummaryThis paper introduces a method called garden balsam optimization algorithm (GBO) for optimization problems. Garden balsam randomly ejects the seeds within a certain range by virtue of mechanical force originating from cracking of mature seed pods. The seeds scattered to suitable growth area will have greater reproductive capacity in the next generation, followed by iteration until the most suitable point for growth in a particular space is eventually found. Mimicking the transmission of garden balsam seeds, GBO generates the seeds by the mechanical transmission and second transmission operator to search the global optimum in the problem space. The convergence of GBO is tested in details through a set of benchmark multi‐dimensional functions. Secondly, the effect of tuning parameters on algorithm performance is studied. Finally, several typical problems were selected in the standard test set to test the performance of GBO. The experimental results show that the algorithm has advantages in optimization problems. In conclusion, the performance of GBO has a reasonable performance for all the test functions.
Origin and development of true karst valleys in response to late Holocene sea‐level change, the Transverse Glades of southeast Florida, USA
Authors: Meeder John F. , Harlem Peter W. 
Published: July 2019

AbstractThe Miami Limestone is an oolite depositional body that is used as an analog model for geological interpretation of the rock record. Barrier‐bar complex, oolite banks, extensive bryozoan flats and tidal creeks, referred to as transverse glades, have been described. High‐resolution LiDAR data are used to produce unprecedented, detailed topographic maps of the transverse glades in the southern Atlantic Coastal Ridge. These maps were originally used to calculate historic discharge from the Everglades but revealed features inconsistent with the prevailing theory that the topography is of a depositional origin. Field observations verified an epikarst terrain truncated by collapsed subsurface conduits creating valleys, previously described as palaeotidal creeks. Observations of the 12 southern tidal creeks or transverse glades provided a sequence of six stages in the development of these karst valleys. After Late Pleistocene deposition of the Miami Limestone, sea‐level dropped producing conditions of: (a) epikarst which reduced the surface elevation preferentially, forming the southern Everglades Basin and modifying Biscayne Bay and Florida Bay precursor basins and (b) downward water movement producing vertical solution features. As Holocene sea‐level approached the South Florida carbonate platform margin a freshwater lens formed and groundwater movement became horizontal. Two sets of cavernous zones developed during the Middle and Late Holocene. Solution pipes and dolines provide a connection between the surface and groundwater along alignments which delineate subsurface conduits. Stages of valley formation are associated with the collapse of these conduits first forming a series of pocket valleys followed by narrow blind valleys and half blind or through valleys linking the Everglades to the coastal plain. Valleys then expanded in width until: (a) completion of cavernous zone collapse, (b) most boulder fields and valley margins reduced by weathering and (c) the valleys filled with wetland soils.
Disentangling herbivore impacts in primary succession by refocusing the plant stress and vigor hypotheses on phenology
Authors: Che‐Castaldo Christian , Crisafulli Charlie M. , Bishop John G. , Zipkin Elise F. , Fagan William F. 
Published: July 2019

AbstractThe plant stress and plant vigor hypotheses are widely used to explain the distribution and abundance of insect herbivores across their host plants. These hypotheses are the subject of contentious debate within the plant herbivore research community, with several studies finding simultaneous support for both hypotheses for the same plant–herbivore interaction. We address the question of how such support is possible using dynamic site‐occupancy models to quantify the attack dynamics of Cryptorhynchus lapathi (poplar‐willow weevil) on Salix sitchensis (Sitka willow), a dioecious shrub colonizing Mount St. Helens, Washington, USA after the 1980 eruption, in relation to host plant stress, vigor, and sex. We also introduce several scaling criteria as a rigorous test of the plant vigor hypothesis and demonstrate why modeling insect detection is important in plant–insect studies. Weevils responded positively to water stress associated with seasonal dry‐downs, and this response was phenologically compartmentalized by larval feeding mode. Weevils preferentially attacked large and/or flowering stems, imposing an ecological cost on willow reproduction via increased stem mortality and susceptibility to future attack. We propose that the dual response to host plant stress and vigor is due to the synchronization between young weevil larval feeding and willow nutrient pulses that are mediated by environmental stress. In turn, this process drives successional dynamics, causing the juvenilization of upland willow plants and possibly delaying establishment of a willow‐dominated upland sere. These results highlight the common, but often overlooked, phenological basis of the plant stress and plant vigor hypotheses, which both focus on how stress changes the quality of plant resources available to immature insects.
Reaping the benefits of cultural diversity: Classroom cultural diversity climate and students’ intercultural competence
Authors: Schwarzenthal Miriam , Schachner Maja K. , Juang Linda P. , van de Vijver Fons J. R. 
Published: July 2019

AbstractCulturally diverse schools may constitute natural arenas for training crucial intercultural skills. We hypothesized that a classroom cultural diversity climate fostering contact and cooperation and multiculturalism, but not a climate fostering color‐evasion, would be positively related to adolescents’ intercultural competence. Adolescents in North Rhine‐Westphalia (N = 631, Mage = 13.69 years, 49% of immigrant background) and Berlin (N = 1,335, Mage = 14.69 years, 52% of immigrant background) in Germany reported their perceptions of the classroom cultural diversity climate and completed quantitative and qualitative measures assessing their intercultural competence. Multilevel structural equation models indicate that contact and cooperation, multiculturalism, and, surprisingly, also color‐evasion (as in emphasizing a common humanity), were positively related to the intercultural competence of immigrant and non‐immigrant background students. We conclude that all three aspects of the classroom climate are uniquely related to aspects of adolescents’ intercultural competence and that none of them may be sufficient on their own.
Development of ulvan‐based emulsions containing flavour and fragrances for food and cosmetic applications
Authors: Morelli Andrea , Massironi Alessio , Puppi Dario , Creti Donato , Domingo Martinez Elia , Bonistalli Camilla , Fabroni Cosimo , Morgenni Fabrizio , Chiellini Federica 
Published: July 2019

AbstractIn the present work, ulvan, a sulphated polysaccharide of algal origin, was innovatively investigated as stabilizing and emulsifying agent in colloidal formulations containing functional agents for food and cosmetic applications in virtue of its edibility and amphiphilic character. Ulvan was successfully submitted to chemical modification with biocompatible fatty acid moieties to increase the amphiphilic properties of the polysaccharide without compromising its safety profile. Oil in water (O/W) emulsions were developed using the ultrasonication method as an easy and rapid homogenization process. The stability of the obtained formulations was assessed by visual inspection, size distribution and zeta potential analysis. Stable emulsions were obtained by using either native or chemically modified polysaccharide. The most promising formulations based on the use of native ulvan were successfully implemented as clouding and flavouring agents in soft drink beverages and as stabilizing and perfuming agents in body cream milk products. The obtained results may open new perspectives on the exploitation of abundant waste biomasses as sources of biocompatible high value added materials suitable for being applied in critical applications as a safe alternative to synthetic chemicals. In particular ulvan could represent a valuable platform of functional and bioactive compounds with promising properties as stabilizing and emulsifying agents for food and cosmetic applications.
Molecular profiling refines minimal residual disease‐based prognostic assessment in adults with Philadelphia chromosome‐negative B‐cell precursor acute lymphoblastic leukemia
Authors: Ribera Jordi , Zamora Lurdes , Morgades Mireia , Vives Susana , Granada Isabel , Montesinos Pau , Gómez‐Seguí Inés , Mercadal Santiago , Guàrdia Ramon , Nomdedeu Josep , Pratcorona Marta , Tormo Mar , Martínez‐Lopez Joaquín , Hernández‐Rivas Jesús‐María , Ciudad Juana , Orfao Alberto , González‐Campos José , Barba Pere , Escoda Lourdes , Esteve Jordi , Genescà Eulàlia , Solé Francesc , Feliu Evarist , Ribera Josep‐Maria ,   on behalf of the Spanish PETHEMA Group,   Spanish Society of Hematology
Published: July 2019

AbstractMinimal residual disease (MRD) assessment is an essential tool in contemporary acute lymphoblastic leukemia (ALL) protocols, being used for therapeutic decisions such as hematopoietic stem cell transplantation in high‐risk patients. However, a significant proportion of adult ALL patients with negative MRD still relapse suggesting that other factors (ie, molecular alterations) must be considered in order to identify those patients with high risk of disease progression. We have identified partial IKZF1 gene deletions and CDKN2A/B deletions as markers of disease recurrence and poor survival in a series of uniformly treated adolescent and adult Philadelphia chromosome‐negative B‐cell progenitor ALL patients treated according to the Programa Español de Tratamientos en Hematología protocols. Importantly, CDKN2A/B deletions showed independent significance of MRD at the end of induction, which points out the need for treatment intensification in these patients despite being MRD‐negative after induction therapy.
Was Permian magmatism in the eastern Songnen and western Jiamusi massifs, NE China, related to the subduction of the Mudanjiang oceanic plate?
Authors: Long Xin‐Yu , Xu Wen‐Liang , Guo Peng , Sun Chen‐Yang , Luan Jin‐Peng 
Published: July 2019

This paper presents new zircon U–Pb ages and Hf isotope data, and whole‐rock major and trace element geochemical data of Permian igneous rocks from the eastern Songnen Massif (SM) and the western Jiamusi Massif (JM), NE China, to constrain their tectonic evolution. Zircon U–Pb dating indicates that Permian magmatism within the eastern SM can be subdivided into two stages: early Permian (ca. 293 Ma) and middle to late Permian (272–257 Ma). The early Permian igneous rocks comprise a bimodal association of rhyolites, basaltic andesites, and gabbros. The middle to late Permian igneous rocks are dominated by gabbro–diorites, monzodiorites, quartz diorites, monzonites, quartz monzonites, granodiorites, monzogranites, syenogranites, and alkali feldspar granites, along with minor bodies of A‐type quartz trachytes. The Permian felsic magmas originated mainly from partial melting of a relatively juvenile lower crust, whereas the coeval mafic rocks were probably derived from partial melting of a relatively depleted lithospheric mantle that was modified by fossil subduction‐related fluids. The igneous rock associations and their geochemical features, together with data from coeval sedimentary and volcanosedimentary successions, indicate that Permian magmatism within the eastern Songnen and western Jiamusi massifs formed in an extensional environment, similar to a back‐arc setting, related to westward subduction of a Palaeo‐oceanic plate beneath the eastern margin of the Jiamusi Massif. We find no evidence for double‐sided subduction of the Mudanjiang oceanic plate during the Permian.
Open chromatin landscape of rat microglia upon proinvasive or inflammatory polarization
Authors: Przanowski Piotr , Mondal Shamba S. , Cabaj Aleksandra , Dębski Konrad J. , Wojtas Bartosz , Gielniewski Bartłomiej , Kaza Beata , Kaminska Bozena , Dabrowski Michal 
Published: July 2019

AbstractMicroglia are brain‐resident, myeloid cells that play important roles in health and brain pathologies. Herein, we report a comprehensive, replicated, false discovery rate‐controlled dataset of DNase‐hypersensitive (DHS) open chromatin regions for rat microglia. We compared the open chromatin landscapes in untreated primary microglial cultures and cultures stimulated for 6 hr with either glioma‐conditioned medium (GCM) or lipopolysaccharide (LPS). Glioma‐secreted factors induce proinvasive and immunosuppressive activation of microglia, and these cells then promote tumor growth. The open chromatin landscape of the rat microglia consisted of 126,640 reproducible DHS regions, among which 2,303 and 12,357 showed a significant change in openness following stimulation with GCM or LPS, respectively. Active genes exhibited constitutively open promoters, but there was no direct dependence between the aggregated openness of DHS regions near a gene and its expression. Individual regions mapped to the same gene often presented different patterns of openness changes. GCM‐regulated DHS regions were more frequent in areas away from gene bodies, while LPS‐regulated regions were more frequent in introns. GCM and LPS differentially affected the openness of regions mapped to immune checkpoint genes. The two treatments differentially affected the aggregated openness of regions mapped to genes in the Toll‐like receptor signaling and axon guidance pathways, suggesting that the molecular machinery used by migrating microglia is similar to that of growing axons and that modulation of these pathways is instrumental in the induction of proinvasive polarization of microglia by glioma. Our dataset of open chromatin regions paves the way for studies of gene regulation in rat microglia.
Early oral cavity cancer: The prognostic factors and impact of adjuvant radiation on survival
Authors: Rajappa Suhas K. , Maheshwari Udip , Ram Dharma , Koyyala Venkata P. B. , Mandal Ghanashyam , Goyal Sumit , Kumar Rajeev , Dewan Ajay K. 
Published: July 2019

AbstractBackgroundEarly oral cavity cancer has good prognosis but recurrence in them is still not uncommon. There is no general consensus on the prognostic factors and adjuvant therapy that would have a significant impact on survival.MethodsA retrospective analysis of early oral cavity cancer patients during the time period 2009‐2017. The data regarding demographics, histopathological features, and recurrence patterns were collected and analyzed.ResultsDepth of invasion (DOI) was the most important prognostic factor among all the factors analyzed. Further analysis showed that addition of adjuvant radiotherapy for patients with DOI >5 mm did not show survival benefits (P = .73). Another subset analysis of patients with DOI >10 mm also did not show any survival advantage with adjuvant therapy P = .24.ConclusionThere is no benefit of adding adjuvant RT in patients with DOI > 5 mm or in patients who were upstaged to T3 based only on DOI.
Robot‐assisted laparoscopic partial nephrectomy for horseshoe kidney: A case report
Authors: Fujihara Atsuko , Hongo Fumiya , Narukawa Tsukasa , Nomura Takeshi , Yamada Yasuhiro , Ukimura Osamu 
Published: July 2019

IntroductionHorseshoe kidney has unique anatomical features, such as a complex blood supply. We report a patient with renal cell carcinoma in a horseshoe kidney, who underwent tumor resection by robot‐assisted laparoscopic partial nephrectomy based on preoperative three‐dimensional computed tomography.Case presentationA 66‐year‐old man was referred to our hospital with a 2‐cm enhancing mid‐pole mass in the left moiety of a horseshoe kidney. The clinical diagnosis was renal cell carcinoma cT1aN0M0 (R.E.N.A.L. nephrometry score: 1 + 2 + 3 + 3 = 9p). Robot‐assisted laparoscopic partial nephrectomy was performed with selective clamping based on reconstructed three‐dimensional images. The warm ischemia time was 13 min. Pathologic examination confirmed a diagnosis of pT1a clear cell renal cell carcinoma with negative surgical margins. At 6 months postoperatively, computed tomography showed no local recurrence or metastasis and renal function was intact.ConclusionRobot‐assisted laparoscopic partial nephrectomy with preoperative three‐dimensional computed tomography may have advantages for resection of tumors in patients with horseshoe kidney.
A multipixel diffuse correlation spectroscopy system based on a single photon avalanche diode array
Authors: Johansson Johannes D. , Portaluppi Davide , Buttafava Mauro , Villa Federica 
Published: July 2019

AbstractThe autocorrelation of laser speckles from coherent near infrared light is used for noninvasive estimates of relative changes in blood perfusion in techniques such as laser Doppler flowmetry (LDF) and diffuse correlation spectroscopy (DCS). In this study, a 2D array of single photon avalanche diodes (SPADs) was used to combine the strengths of multiple detectors in LDF with high light sensitivity in DCS. The system was tested on milk phantoms with varying detector fiber diameter (200 and 600 μm), source‐detector fiber separation (4.6‐10.2 mm), fiber‐SPAD distance (2.5‐36.5 mm), contiguous measurement time per repetition for the autocorrelation (1‐33 ms) and temperature (15.6‐46.7°C). An in vivo blood occlusion test was also performed. The multipixel approach improved signal‐to‐noise ratio (SNR) and, in our setup, the use of a multimode detector fiber was beneficial for SNR. In conclusion, the multipixel system works, but improvements and further studies regarding, for example, the data acquisition and optimal settings are still needed.
Artificial intelligence in accounting: GAAP's “FAS133”
Authors: Le Guyader Louis P. 
Published: July 2019

AbstractArtificial intelligence (AI) is the necessary element to ensure that the most complex modern accounting rules are implemented correctly. This is particularly true when accounting interacts with increasingly sophisticated capital markets activities. The last 20 years' of accounting rulemaking and the dictates of regulators have ensured a need for AI. With user‐friendly AI solutions, reporting entities will not shy away from business practices because they fear they cannot account for them correctly. AI will remain an opportunity and challenge to the accounting profession.
Abnormally expressed long noncoding RNA B3GALT5‐AS1 may serve as a biomarker for the diagnostic and prognostic of gastric cancer
Authors: Feng Wei , Zong Wei , Li Yi , Shen Xianjuan , Cui Xiaopeng , Ju Shaoqing 
Published: July 2019

AbstractEarly diagnosis of gastric cancer (GC) is an effective method to improve prognosis. Increasing number of long noncoding RNAs (lncRNAs) have been reported as biomarkers for several cancers. We aim to detect the level of lncRNA B3GALT5‐AS1 and its association with clinical parameters and to further explore its application value in GC. We measured serum B3GALT5‐AS1 expression in 107 patients with GC, 40 polyp patients, and 87 normal controls to explore the significance of serum B3GALT5‐AS1 in GC using the quantitative real‐time polymerase chain reaction method. The result demonstrated that B3GALT5‐AS1 level was markedly richer in GC patients than that in normal people (P < .001). B3GALT5‐AS1 may be served as a diagnostic marker for distinguishing GC patients from healthy people, and the proportion under the receiver operating characteristics curve is 0.816 (95% confidence interval, 0.758‐0.874; P = .03). Further exploration validated that high serum B3GALT5‐AS1 level was related to TNM stage (P = .024), and lymph node metastasis (P = .023). Our study suggested that serum B3GALT5‐AS1 may be employed as an ideal biomarker for early screening of GC.