bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABA-ergic Parvalbumin Interneurons Attenuates Chronic Stress Adaptions in Male Mice
Authors: Nawreen Nawshaba , Morano Rachel , Mahbod Parinaz , Cotella Evelin M. , Dalal Khushali , Fitzgerald Maureen , Martelle Susan , Packard Benjamin A. , Moloney Rachel D. , Herman James P. 
Published: October 2019

ABSTRACTHypofunction of the prefrontal cortex (PFC) contributes to stress-related neuropsychiatric illnesses. Mechanisms leading to prefrontal hypoactivity remain to be determined. Prior evidence suggests that enhanced activity of parvalbumin (PV) expressing GABAergic interneurons (INs) play a role in chronic stress related pathologies. In this study, the role of PFC PV INs in stress related phenotypes were explored using Cre inducible inhibitory DREADDs (Designer Receptors Exclusively Activated by Designer Drugs). Mice were first tested in the tail suspension test (TST) to determine the effects of PV IN inhibition during acute stress. Following this, the long term impact of PV IN inhibition during chronic variable stress (CVS) was tested in the forced swim test (FST). Acute PV IN inhibition reduced active (struggling) and increased passive coping behaviors (immobility) in the TST. In contrast, inhibition of PV INs during CVS increased active and reduced passive coping behaviors in the FST. Moreover, chronic inhibition of PV INs attenuated CVS-induced changes in Fos expression in the prelimbic cortex, basolateral amygdala and ventrolateral periaqueductal gray and also prevented adrenal hypertrophy and body weight loss associated with chronic stress. Our results suggest differential roles of PV INs to acute vs chronic stress, indicative of distinct biological mechanisms underlying acute vs. chronic stress responses. Our results also indicate a role for PV INs in driving chronic stress adaptation and support literature evidence suggesting cortical GABAergic interneurons as a therapeutic target in stress related diseases.SIGNIFICANCEStress related diseases are associated with prefrontal hypoactivity, the mechanism of which is currently not known. In this study we showed that by inhibiting prefrontal GABA-ergic Parvalbumin interneurons (PV INs) using DREADDs, we can attenuate some of chronic stress related phenotypes. Additionally, we showed that modulation of PV IN activity during acute vs chronic stress had opposing effects on stress coping strategies, suggesting different underlying mechanisms behind acute vs chronic stress paradigms. Our findings indicate that GABA-ergic PV INs may be involved in driving stress related phenotypes and thereby an important target for treatment of stress-related illnesses. Our data suggest that reducing PV IN activity to promote prefrontal output may be an effective treatment strategy for stress related disorders.
Differential degradation of RNA species by autophagy related pathways in plants
Authors: Hickl D. , Drews F. , Girke C. , Zimmer D. , Mühlhaus T. , Hauth J. , Nordström K. , Trentmann O. , Neuhaus H.E. , Fehlmann T. , Keller A. , Simon M. , Möhlmann T. 
Published: October 2019

AbstractAn important function of the plant vacuole is the recycling of the delivered proteins and RNA by autophagy. We provide the first plant vacuolar small RNome by isolation of intact vacuoles from Barley and Arabidopsis, subsequent RNA purification and Next Generation Sequencing. In these vacuolar sRNomes, all types of cellular RNAs were found including those of chloroplast origin, suggesting a bulk-type of RNA transfer to, and breakdown in vacuoles. ATG5 is a major representative of autophagy genes and the vacuolar RNA composition in corresponding knockout plants differed clearly from controls as most chloroplast derived RNA species were missing. Moreover, the read length distribution of RNAs found in ATG5 mutants differed to control samples, indicating altered RNA processing. In contrast, vacuolar RNA length and composition of plants lacking the vacuolar RNase2 (rns2-2), involved in cellular RNA homeostasis, showed minor alterations, only. Our data therefore suggests that mainly autophagy components are responsible for selective transport and targeting of different RNA species into the vacuole for degradation. In addition, mature miRNAs were detected in all vacuolar preparations, however in ATG5 mutants at much lower frequency, indicating a new biological role for vacuolar miRNAs apart from becoming degraded.
The impact of financial leverage on farm technical efficiency during periods of price instability
Authors: Gadanakis Yiorgos , Stefani Gianluca , Lombardi Ginerva Virginia , Tiberti Marco 
Published: October 2019

PurposeThe purpose of this paper is to provide empirical evidence on the relationship between capital structure and technical efficiency (TE) for Italian cereal farms during the 2008–2014 period. Emphasis is given in the understanding of the relationship between the level of financial leverage for cereal farms and their production performance.Design/methodology/approachThe methods employed in this research article are based on non-parametric techniques in order to derive TE estimates for a sample of Italian cereal farms based on available Farm Accountancy Data Network data to explore in depth the relationship amongst the financial exposure of the sector and the capacity to utilise an efficient and effective production technology. Furthermore, subsidies are considered in the model as a non-discretionary variable and therefore, as an input that farmers cannot directly influence within the production function. Hence, the non-discretionary Data Envelopment Analysis model is a more appropriate framework since it is not penalising farms at a lower level of Pillar I payments when benchmarked with farms that receive a higher level of payments.FindingsThe results show that significant improvements could be achieved for most of the farms in the sample by improving production and management practices. Furthermore, results provide an empirical support of the adjustment theory by showing a negative impact of debt to asset ratio to TE.Originality/valueThis research article provides a first insight on the evolution of the Italian cereal farms debt-TE relationship in periods where high price instability has been observed.
Credit sources, access and factors influencing credit demand among rural livestock farmers in Nigeria
Authors: Silong Asenath Kotugan Fada , Gadanakis Yiorgos 
Published: October 2019

Purpose
Rural farmers’ access to farm credit in Nigeria has been very low, which affects farm performance, and credit providers have blamed for the problem in the sector. While this general perception persists the fact may be the case of credit demand, rather than just the risk-averse attitudes of credit providers. The purpose of this paper is to investigate significant factors influencing farmers’ credit demand to ensure efficient credit provision.

Design/methodology/approach
The research adopted mixed methods for an in-depth investigation into the problem. There were 216 research participants split into equal halves of men and women from six local government areas of Nasarawa State. Data collection methods employed structured interviews, focus group discussions, close/open-ended and key informant interviews. Analytical tools involved descriptive statistics, the logit and multinomial logit models to determine participants’ socio-economic characteristics, sources of credit, access, factors influencing credit demand generally and from the various sources of credit identified.

Findings
Findings reveal only 47.6 per cent of the participants accessed credit, with fewer women accessing than men. The most accessed forms of credit are from the semi-formal sources, with more men accessing from formal sources and more women from non-formal sources. Factors having significant influence on credit demand generally are education, group membership and household size. And from formal, semi-formal and non-formal credit sources are education, information on sources of credit, deposits, household size and marital status; education, deposits, group membership, household size, flock size; and education, group membership, and gender from the non-formal credit providers, respectively.

Research limitations/implications
Due to time constraint, this study data were collected concurrently with both quantitative and qualitative methods and did not allow for the interrogation of findings from one method with the other. In addition, the research categorised the agency of women based on marital status only as single or married and did not interrogate the agency of women further, this may be a limitation as some of the female participants are from polygamous homes.

Originality/value
Unlike the current concentration of Nigerian research of this kind with quantitative methods alone, this research contributes particularly to Nigerian research output and experience by triangulating both quantitative and qualitative methods to explore farmers sources of credit, access and factors determining access to credit in the study area.
Awareness and compliance with feed quality standards: the case of chicken feeds in Tanzania
Authors: Longo Joseph Adam , Akyoo Adam Meshack , Sørensen Olav Jull 
Published: October 2019

Purpose
The purpose of this paper is to examine the determinants of awareness of and compliance with chicken feed standards among chicken farmers in Tanzania.

Design/methodology/approach
A total of 107 respondents in two regions were selected through simple random sampling. Structured questionnaires were used to collect data. Descriptive statistics and multiple regression approaches were used in data analysis.

Findings
The results revealed that the level of awareness of standards is low and the compliance level is even lower at the same time as the data indicated a positive relation between awareness and compliance. Attending seminars, knowledge dissemination by extension agents, farmers’ awareness of the existence of other standards and health consciousness have a significant and positive influence on awareness of feed standards while the age of the farm and dependence on farm formulated feeds have a significant negative influence on awareness of standards. On the other hand; knowledge dissemination by TBS, awareness of chicken feed standards and awareness of the existence of other standards apart from chicken feed standards, have a significant positive influence on compliance with feed standards.

Research limitations/implications
These findings indicate that regulators should invest more in awareness creation campaigns to enhance compliance with feed standards at the same time as feed processors should develop closer knowledge and learning links to farmers.

Originality/value
The findings of the study are expected to positively contribute to performance of chicken industry in Tanzania by promoting production of products that are of quality accepted domestically and abroad.
Considerations for collecting Japanese anime for academic libraries
Authors: Masuchika Glenn 
Published: October 2019

Purpose
Too often, academic library selectors of DVDs purchase Japanese animation (anime) for their popularity without any further concern of their important contributions to the combined wealth of researches of an academic library. The purpose of this paper is to offer considerations for an academic selector to ponder before adding this particular type of animation. These considerations do not necessary pertain to the collection development considerations for selectors at public libraries.

Design/methodology/approach
This paper will discuss the major problems of actively adding anime to an academic library, the present areas of concern, and will offer warnings and suggestions based on a conceptual framework of anime having true academic value.

Findings
Anime cannot be chosen independently as if it has any apparently intrinsic value sui generis. Anime must be added concomitantly according to the collection development policies with other resources, especially DVDs, to create a full, rich and useful collection to scholars.

Originality/value
Academic studies concerning anime and collection development for academic libraries are usually comprised of only long lists of suggested anime, with no further discussions about its implications to the general worth of an academic library. This paper offers no such lists. Instead, it offers considerations selectors must take into account before investing time and money adding anime to an academic library collection.
Structure behind principles: social selection mechanisms in corporate governance networks
Authors: Kacanski Slobodan 
Published: October 2019

PurposeThe purpose of this study is to show that social relations in a corporate governance platform between members of supervisory boards and between members of supervisory and executive board tiers can serve as an alternative viewpoint for understanding mechanisms of social selection in corporate governance networks. The study shows that through the lenses of social network analysis, it is possible to identify and understand how the process of corporate governance member selection unfolds within companies and how that selection process may have been potentially influenced by the cross-board relations, such as interlocking directorships.Design/methodology/approachTo estimate network parameters and attribute effects of network tie emergence, this study has used exponential random graph models (ERGMs) on corporate governance data of Danish publicly listed companies. Econometric models are applied to estimate parameter statistics which serve further to explain tendencies of tie emergence.FindingsThe results of this study reveal that the process of selection of both supervisory boards and executive directors is interdependent. Also, the study showed that board members are more likely to select popular supervisory board members and top managers who have their expertise gained through multiple companies affiliated with multiple industries. However, these conditions for CEO selection apply only to the extent to which they have their experience gained from multiple companies but not multiple industries.Originality/valueOn one hand, this study demonstrates that being a dynamic practitioner who is exposed to diverse corporate environments by being affiliated with different companies belonging to different industries generally increases practitioners visibility in the corporate governance network, and therefore their attractiveness to boards of directors. On the other hand, the results show that the research on board assemblage, nowadays, should be rather observed through the methodology of social network analysis as the method gives an opportunity to understand structures through relations, from which the executive tier should not be exempted as well.
Missing “society” in institutional approaches as social value creation in India and China
Authors: Oh Chang Hoon 
Published: October 2019

Purpose
This viewpoint aims to discuss some potential problems of institutional approaches such as social value creation in India and China.

Design/methodology/approach
In this viewpoint, institutional approaches as social value creation in India and China have been discussed and compared.

Findings
Government-driven institutional approaches may not be efficient because the involvement of political interests would prevail in countries with low institutional quality, firms focusing on international markets need to adopt global guidelines and regulatory guidelines set by governments and private sectors could ignore the differences and needs of various stakeholders.

Originality/value
This viewpoint argues the importance of communications and collaborations among governments, private sectors and other stakeholders in creating social values.
Building an integrated enhanced virtual research environment metadata catalogue
Authors: Remy Laurent , Ivanović Dragan , Theodoridou Maria , Kritsotaki Athina , Martin Paul , Bailo Daniele , Sbarra Manuela , Zhao Zhiming , Jeffery Keith 
Published: October 2019

Purpose
The purpose of this paper is to boost multidisciplinary research by the building of an integrated catalogue or research assets metadata. Such an integrated catalogue should enable researchers to solve problems or analyse phenomena that require a view across several scientific domains.

Design/methodology/approach
There are two main approaches for integrating metadata catalogues provided by different e-science research infrastructures (e-RIs): centralised and distributed. The authors decided to implement a central metadata catalogue that describes, provides access to and records actions on the assets of a number of e-RIs participating in the system. The authors chose the CERIF data model for description of assets available via the integrated catalogue. Analysis of popular metadata formats used in e-RIs has been conducted, and mappings between popular formats and the CERIF data model have been defined using an XML-based tool for description and automatic execution of mappings.

Findings
An integrated catalogue of research assets metadata has been created. Metadata from e-RIs supporting Dublin Core, ISO 19139, DCAT-AP, EPOS-DCAT-AP, OIL-E and CKAN formats can be integrated into the catalogue. Metadata are stored in CERIF RDF in the integrated catalogue. A web portal for searching this catalogue has been implemented.

Research limitations/implications
Only five formats are supported at this moment. However, description of mappings between other source formats and the target CERIF format can be defined in the future using the 3M tool, an XML-based tool for describing X3ML mappings that can then be automatically executed on XML metadata records. The approach and best practices described in this paper can thus be applied in future mappings between other metadata formats.

Practical implications
The integrated catalogue is a part of the eVRE prototype, which is a result of the VRE4EIC H2020 project.

Social implications
The integrated catalogue should boost the performance of multi-disciplinary research; thus it has the potential to enhance the practice of data science and so contribute to an increasingly knowledge-based society.

Originality/value
A novel approach for creation of the integrated catalogue has been defined and implemented. The approach includes definition of mappings between various formats. Defined mappings are effective and shareable.
The street party: pleasurable community practices and placemaking
Authors: Stevenson Nancy 
Published: October 2019

Purpose
The purpose of this paper is to explore spatial and social practices associated with a community street party through the lens of literature on encounter, conviviality and placemaking, considering its role developing a place-based sense of community.

Design/methodology/approach
The research is based upon a case study of a street party in London. Data sources include interviews, a questionnaire, observation and a literature review.

Findings
The conviviality associated with partying disrupts mundane social relations and engages diverse communities in placemaking. People playfully engage with one another, performing and reinforcing community and place values in the environment outside their homes.

Practical implications
This paper aims to engender understanding and encourage urban policy makers to support activities which combine pleasure and play to develop a place-based sense of community. It identifies practices which actively engage people at a grassroots level and enable them to articulate and perform community values.

Social implications
Developing a sense of community in rapidly changing and diverse urban areas presents challenges for urban policy makers. Grassroots activities such as street parties often fall outside of funding streams, debates and formal policy making for cities but it is argued here that they enable people to engage in pleasurable and playful interaction and have an important role in disrupting mundane interactions and connecting people.

Originality/value
This paper progresses discussion of community events from a social perspective through an original study, identifying specific practices which contribute to a place-based sense of community.
Influence of situational factors on household’s energy consumption behaviour
Authors: Kuhe Aondoyila , Bisu Danladi Yusufu 
Published: October 2019

Purpose
This paper aims to present a systematic scoping review of the influences of some situational factors on the energy consumption behaviour of households. Household’s energy choice and manner of utilization define its energy consumption behaviour; it is a key factor in determining the energy efficiency of households. Despite the energy-efficient technological innovations and awareness on environmental/health implications of using certain energy sources and technologies, households still use inefficient, traditional energy sources and technologies. Some researchers have attempted to use economic and psychological theories to explain the situation with the hope of achieving a change in behaviour towards sustainable energy utilization but to no avail. This is because the theories fail to consider situations beyond individuals or households. A clear understanding of situational factors and how they influence household energy behaviour will provide information that will aid deeper research and policy formulation towards sustainable energy behaviour of households.

Design/methodology/approach
A scoping systematic review of available literature regarding real-life cases in both developed and developing countries was carried out to determine the possibility of situational factors affecting household energy choices and utilization.

Findings
The result of the review showed that situational factors have a significant influence on household’s energy consumption. The main policy implications observed are the need for laws that will encourage energy-saving renovations in houses, make compulsory the provision of recreational facilities in residential areas to reduce in-home energy consumption. The need for increased access to electricity and other efficient energy sources and cooking technologies has also been observed. Intensive awareness campaigns are required to disabuse the minds of people about cultural issues that mitigate improved cook stove adoption.

Originality/value
The paper provides information on the influence of some of the factors, which affect energy consumption in households, which fluctuate depending on the current situation of the consumer and are time-bound (situational factors). The information will help policymakers and regulators to understand the influence of situational factors on household energy consumption, thereby enabling them to make policies that will enhance sustainable energy consumption.