bluuebunny/crossref_metadata_2025_split huggingface dataset:
Jóvenes conscriptos argentinos en tres espacios de movilización militar, década de los años setenta
Authors: Di Renzo Cristian Andrés , Mosiewicki Francisco 
Published: February 2019

El artículo tiene como objetivo analizar la forma como jóvenes conscriptos argentinos fomentaron el ideal patriótico en tres casos de movilización militar: la destitución del presidente de facto Juan Carlos Onganía (1970), el llamado «Operativo Independencia» (1975) y el «Operativo Soberanía» (1978). En los tres casos seleccionados, se desarrollaron concepciones acerca del esfuerzo que la patria demandaba de los jóvenes que cumplían con su deber cívico dentro del servicio militar obligatorio. A su vez, en lo cotidiano, la experiencia bélica matizó tales lineamientos a la luz de las propias concepciones que los conscriptos tenían de lo que implicaba el deber. Partiendo de la metodología que aporta el campo de la historia de las emociones, se buscará entonces, comprender el cruce entre los esfuerzos por condicionar las experiencias emotivas de los jóvenes y la formación de contradiscursos y espacios de contra hegemonía. Asimismo, la puesta en valor de conceptos tales como «nacionalismo banal», permitirá debatir sobre las diversas formas que la identidad nacional constituyó, en tres coyunturas particulares que incentivaron la instauración de un fervor bélico nacional.
Horizontal-Steam-Injection-Flow Profiling Using Fiber Optics
Authors: Shirdel M.. , Buell R. S. , Wells M. J. , Muharam C.. , Sims J. C. 
Published: February 2019

Summary
Steam-conformance control in horizontal injectors is important for efficient reservoir-heat management in heavy-oil fields. Suboptimal conformance and nonuniform heating of the reservoir can substantially affect the economics of the field development and oil-production response and result in nonuniform steam breakthrough. To achieve the required control, it is essential to have an appropriate well-completion architecture and robust surveillance.
Five fiber-optic systems, each with a unique steam-conformance-control-completion configuration, have been installed in two horizontal steam injectors to help mature steam-injection-flow profiling and conformance-control solutions. These fiber-optic systems have used custom-designed fiber-optic bundles of multimode and single-mode fibers for distributed-temperature sensing (DTS) and distributed-acoustic sensing (DAS), respectively. Fiber-optic systems were also installed in a steam-injection-test-flow loop. All the optical fibers successfully acquired data in the wells and flow loop, measuring temperature and acoustic energy.
A portfolio of algorithms and signal-processing techniques was developed to interpret the DTS and DAS data for quantitative steam-injection-flow profiling. The heavily instrumented flow-loop environment was used to characterize DTS and DAS response in a design-of-experiment (DOE) matrix to improve the flow-profiling algorithms. These algorithms are dependent on independent physical principles derived from multiphase flow, thermal hydraulic models, acoustic effects, large-data-array processing, and combinations of these methods for both transient and steady-state steam flow. A high-confidence flow profile is computed using the convergence of the algorithms. The flow-profiling-algorithm results were further validated using 11 short-offset injector observation wells wells in the reservoir that confirmed steam movement near the injectors.
Determination of Petrophysical Properties by Stereological Techniques
Authors: Perez-Rosales Candelario , Martinez Juan Jose 
Published: February 2019

SPEJ Forum articles are limited to 1,500 words including 250 words for each table and figure, or. a maximum of two pages in SPEJ. A Forum article may present preliminary results or conclusions of an investigation that the author wishes to publish before completing a full study; it may impart general technical information that does not warrant publication as a full-length paper. All Forum articles are subject to approval by an editorial committee.

ABSTRACT
Stereology has been defined as the study of microscopic three-dimensional systems based on the analysis of two-dimensional sections. This article describes a stereological technique for the quantitative evaluation of physical properties of sedimentary rocks such as porosity, formation resistivity factor, and permeability. The results obtained by the proposed method show a fairly good agreement with those obtained by conventional methods.

INTRODUCTION
Stereology may be defined as the quantitative evaluation of microstructures by means of the analysis of two-dimensional sections.1 Examples of structures that can be studied through the use of stereological techniques are organic tissue, rocks, minerals, alloys, and aggregates of particles. Stereology has found a variety of applications in disciplines such as biology, metallurgy, geology, petrology, and other related fields. In recent years, the importance of stereology has been increased considerably due to the development of new electronic devices for the automatic analysis of images.
In this article, a study on the application of stereological techniques to the determination of physical properties of sedimentary rocks is presented. This is an area that has received little attention in the past. It is believed, however, that it offers good perspectives in research work and routine operations.
Gender Bias in Javanese Society: A Study in Language Forms Choice to Men and Women
Authors: Atmawati Dwi 
Published: February 2019

This research aimed to reveal different ways of thinking of society for men’s and women’s positions from the sociolinguistic point of view to accomplish the previous research. The research was conducted by studying language data in sentence formation on short story (fiction) and article (nonfiction). The short story and article used as data sources originated from internet media. This research used a qualitative descriptive method. The data were analyzed using equality and distributional methods. The finding data are classified into two: language form choice difference is based on linguistic factor and non-linguistic factor. Linguistic factor includes morphology, lexicon, phrase, compounds words, idiom. Non-linguistic factor includes the use of husband’s and wife’s names; call of husband’s name after wife’s proper name. The research shows that gender bias in Javanese society is expressed in differences in language forms choice to men and women. The language forms obtained from the data covers differences in language forms choice as caused by a social way of thinking to men’s and women’s status in daily life.
Failure Factors among Young Entrepreneurs in Higher Education Institution: A Study from Telkom University
Authors: Setiawati Cut Irna , Atarita Abi 
Published: February 2019

The purpose of this research was to determine factors that caused the failure of young entrepreneurs in Telkom University among the participants of 2016-2017 competition and exhibition. This research applied a quantitative method with a descriptive and explorative research type. Techniques of collecting data were using questionnaires. This research used the nonprobability sampling method that was saturated sampling because of all members of the population of 116 respondents in this research. Data analysis was using Principal Component Analysis (PCA). The results show the five new factors causing the failure among young entrepreneurs in Telkom University who participate in the Business Plan Competition and Creative Market Exhibition in 2017, are: (1) improper asset and marketing management, (2) unqualified entrepreneurial characteristics, (3) unwell anticipation of capital and regulation pressure, (4) financial and non-financial failures, and (5) ignored by the owner.
Firms’ Dynamic Capabilities: A Case of Indonesian Telecommunication Company
Authors: Apriza Sari , Utami Ami Fitri 
Published: February 2019

Based on the concept of dynamic capabilities that were introduced by Teece & Pisano, this research aimed to analyze how did the dynamic capability condition in Company A. This research used a descriptive qualitative method of secondary data from annual report 2013 to 2017 and article in the website. It is found that Company A possesses a dynamically fluctuate dynamic capabilities through their ability to absorptive capability, adaptive capability, and innovative capability. The implementation of dynamic capabilities in Company A depend on top management board member to develop the company’s general strategic move and by this able to maintain the dynamic capability, and Telecommunication company should be able to nurture the whole organizations’ environment which supports the proliferation of this capability to all the members inside. In short, the benefit of this research will give learning point for the business player or practical to deal with the dynamic situation by using a dynamic capabilities perspective.
Electrocoagulation using commercial grade aluminium electrode for the removal of crystal violet from aqueous solution
Authors: Vidya Vijay E. V. , Jerold M. , Ramya Sankar M. S. , Lakshmanan Sanjay , Sivasubramanian V. 
Published: February 2019

AbstractThe current research work studies the removal of crystal violet (also known as gentian violet), a kind of dye, from simulated wastewater by electrocoagulation using scrap aluminium roofing sheet as electrode in a batch electrochemical cell. Optimization of different operational parameters – pH, current density, time, initial concentration – was carried out experimentally. The equilibrium was attained at 1 hour and at pH 11. After suitable optimization, a removal of above 90% was achieved at an optimum current density of 20 mA/m2. Also, the adsorption behaviour of crystal violet in electrocoagulation was also studied and the isothermal and kinetic models were proposed to be the Dubinin–Radushkevich model and pseudo-first order model. The mechanism involved during the process was suggested as chemisorption. The adsorption thermodynamic studies were a clear indication that the process is spontaneous and endothermic as well as thermodynamically favourable too. Both chemical and physical characterization of the flocs generated during the electrolysis was explained by Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) respectively.
Separation, Characterization and Discriminant Analysis of Subvisible Particles in Biologics Formulations
Authors: Akhunzada Zahir S. , Hubert Mario , Sahin Erinc , Pratt James 
Published: February 2019

Background:The presence of subvisible particles (SVPs) in parenteral formulations of biologics is a major challenge in the development of therapeutic protein formulations. Distinction between proteinaceous and non-proteinaceous SVPs is vital in monitoring formulation stability.Methods:The current compendial method based on light obscuration (LO) has limitations in the analysis of translucent/low refractive index particles. A number of attempts have been made to develop an unambiguous method to characterize SVPs, albeit with limited success.Results:Herein, we describe a robust method that characterizes and distinguishes both potentially proteinaceous and non-proteinaceous SVPs in protein formulations using Microflow imaging (MFI) in conjunction with the MVAS software (MFI View Analysis Suite), developed by ProteinSimple. The method utilizes two Intensity parameters and a morphological filter that successfully distinguishes proteinaceous SVPs from non-proteinaceous SVPs and mixed aggregates.Conclusion:he MFI generated raw data of a protein sample is processed through Lumetics LINK software that applies an in-house developed filter to separate proteinaceous from the rest of the particulates.
Structure and Function of Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) in Hyperlipidemia and Atherosclerosis
Authors: Lu Xinjie 
Published: February 2019

Background:One of the important factors in Low-Density Lipoprotein (LDL) metabolism is the LDL receptor (LDLR) by its capacity to bind and subsequently clear cholesterol derived from LDL (LDL-C) in the circulation. Proprotein Convertase Subtilisin-like Kexin type 9 (PCSK9) is a newly discovered serine protease that destroys LDLR in the liver and thereby controls the levels of LDL in plasma. Inhibition of PCSK9-mediated degradation of LDLR has, therefore, become a novel target for lipid-lowering therapy.Methods:We review the current understanding of the structure and function of PCSK9 as well as its implications for the treatment of hyperlipidemia and atherosclerosis.Results:New treatments such as monoclonal antibodies against PCSK9 may be useful agents to lower plasma levels of LDL and hence prevent atherosclerosis.Conclusion:PCSK9's mechanism of action is not yet fully clarified. However, treatments that target PCSK9 have shown striking early efficacy and promise to improve the lives of countless patients with hyperlipidemia and atherosclerosis.
Hetero-Tricyclic Lead Scaffold as Novel PDE5A Inhibitor for Antihypertensive Activity: In Silico Docking Studies
Authors: Mali Dipak P. , Bhatia Neela M. 
Published: February 2019

Objective:To screen the phytochemicals for phosphodiesterase 5A (PDE5A) inhibitory potential and identify lead scaffolds of antihypertensive phytochemicals using in silico docking studies.Methods:In this perspective, reported 269 antihypertensive phytochemicals were selected. Sildenafil, a PDE5A inhibitor was used as the standard. In silico docking study was carried out to screen and identify the inhibiting potential of the selected phytochemicals against PDE5A enzyme using vLife MDS 4.4 software.Results:Based on docking score, π-stacking, H-bond and ionic interactions, 237 out of 269 molecules were selected which have shown one or more interactions. Protein residue Gln817A was involved in H-boding whereas Val782A, Phe820A and Leu804A were involved in π-stacking interaction with ligand. The selected 237 phytochemicals were structurally diverse, therefore 82 out of 237 molecules with one or more tricycles were filtered out for further analysis. Amongst tricyclic molecules, 14 molecules containing nitrogen heteroatom were selected for lead scaffold identification which finally resulted in three different basic chemical backbones like pyridoindole, tetrahydro-pyridonaphthyridine and dihydro-pyridoquinazoline as lead scaffolds.Conclusion:In silico docking studies revealed that nitrogen-containing tetrahydro-pyridonaphthyridine and dihydro-pyridoquinazoline tricyclic lead scaffolds have emerged as novel PDE5A inhibitors for antihypertensive activity. The identified lead scaffolds may provide antihypertensive lead molecules after its optimization.
Uji Aktivitas Antijamur Sari Buah Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Jamur Candida albicans
Authors: Octaviani Melzi , Fadila Fadila 
Published: February 2019

<em>Uji aktivitas antijamur sari buah belimbing wuluh (Averrhoa bilimbi L.) terhadap jamur Candida albicans telah dilakukan dengan menggunakan metode dilusi padat. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur sari buah belimbing wuluh (Averrhoa bilimbi L.) terhadap jamur Candida albicans. Hasil penelitian menunjukkan adanya penurunan jumlah koloni jamur yang diperoleh pada konsentrasi 100%, 80%, 60%, 40% dan 20% berturut-turut dengan persentase 55%, 48%, 40%, 30% dan 0,16% terhadap pertumbuhan jamur uji. Hasil uji statistik one way ANOVA menunjukkan nilai p&lt;0,05 (p=0,000) yang berarti seluruh konsentrasi menunjukkan adanya perbedaan signifikan antar seluruh kelompok perlakuan</em>
Antisense Inhibition of Glucagon Receptor by IONIS-GCGRRx Improves Type 2 Diabetes Without Increase in Hepatic Glycogen Content in Patients With Type 2 Diabetes on Stable Metformin Therapy
Authors: Morgan Erin S. , Tai Li-Jung , Pham Nguyen C. , Overman Julia K. , Watts Lynnetta M. , Smith Anne , Jung Shiangtung W. , Gajdošík Martin , Krššák Martin , Krebs Michael , Geary Richard S. , Baker Brenda F. , Bhanot Sanjay 
Published: February 2019

OBJECTIVE
To evaluate the safety and efficacy of IONIS-GCGRRx, a 2′-O-methoxyethyl antisense oligonucleotide targeting the glucagon receptor (GCGR), and the underlying mechanism of liver transaminase increases in patients with type 2 diabetes on stable metformin therapy.

RESEARCH DESIGN AND METHODS
In three phase 2, randomized, double-blind studies, patients with type 2 diabetes on metformin received weekly subcutaneous injections of IONIS-GCGRRx (50–200 mg) or placebo for 13 or 26 weeks.

RESULTS
Significant reductions in HbA1c were observed after IONIS-GCGRRx treatment versus placebo at week 14 (−2.0% 200 mg, −1.4% 100 mg, −0.3% placebo; P &lt; 0.001) or week 27 (−1.6% 75 mg, −0.9% 50 mg, −0.2% placebo; P &lt; 0.001). Dose-dependent increases in transaminases were observed with IONIS-GCGRRx, which were attenuated at lower doses and remained mostly within the normal reference range at the 50-mg dose. There were no other significant safety observations and no symptomatic hypoglycemia or clinically relevant changes in blood pressure, LDL cholesterol, or other vital signs. At week 14, IONIS-GCGRRx 100 mg did not significantly affect mean hepatic glycogen content compared with placebo (15.1 vs. −20.2 mmol/L, respectively; P = 0.093) but significantly increased hepatic lipid content (4.2 vs. −2.7%, respectively; P = 0.005) in the presence of transaminase increases.

CONCLUSIONS
IONIS-GCGRRx is a potent inhibitor of hepatic glucagon receptor expression with a potential to improve glycemic control at low weekly doses in combination with metformin. Significant reductions in HbA1c occurred across the full-dose range tested, with minimal transaminase elevations at lower doses. Furthermore, novel results suggest that despite inhibition of glycogenolysis after GCGR antagonism, IONIS-GCGRRx did not increase hepatic glycogen content.
Diabetes Distress, Intentional Hyperglycemia at Work, and Glycemic Control Among Workers With Type 1 Diabetes
Authors: Hansen Ulla M. , Skinner Timothy , Olesen Kasper , Willaing Ingrid 
Published: February 2019

OBJECTIVE
The aim was to explore relationships between work-related factors, work-related diabetes distress (WRDD), diabetes distress (measured by Problem Areas in Diabetes [PAID]-5 scale), intentional hyperglycemia at work (IHW), and glycemic control.

RESEARCH DESIGN AND METHODS
A cross-sectional survey was conducted with 1,030 working adults with type 1 diabetes and linked with electronic health record data from a specialist diabetes clinic in Denmark. With use of structural equation modeling, two alternative models were compared, based on fit indices, statistical significance, and theoretical meaningfulness.

RESULTS
A combined model provided the best fit to the data. WRDD was more strongly affected by work ability, opportunity to self-manage at work, being treated differently, and job demands. PAID-5 was more strongly affected by identity concern and blame and judgment. Both PAID-5 and WRDD were associated with more frequent IHW, which was associated in turn with worse glycemic control.

CONCLUSIONS
Work-related factors are associated with WRDD and PAID-5. Distress increases the frequency of IHW, which is, in turn, associated with worse glycemic control. Future studies should investigate ways to balance diabetes management and work life without compromising diabetes care.
Tests of Residual Shear Transfer Strength of Concrete Exposed to Fire
Authors: Shallal Muhaned A. , Musawi Aqil Mousa K. Al 
Published: February 2019

AbstractReinforced concrete is one of the most widely used structural components about which much scientific research has been conducted; however, some of its characteristics still require further research. The main focus of this study is the effect of direct fire on the shear transfer strength of concrete. It was investigated under several parameters including concrete strength, number of stirrup legs (the steel area across the shear plane), and fire duration. The experimental program involved the testing of two sets (groups) of specimens (12 specimens each) with different concrete strengths. Each set contained specimens of two or four stirrup legs exposed to direct fire from one side (the fire was in an open area to simulate a real-life event) for a duration of one, two, and three hours. The results of the comparison showed the importance of using high-performance concrete (instead of increasing the number of stirrup legs) to resist shear stress for the purpose of safety. A significant reduction in shear strength occurred due to the deterioration of the concrete cover after three hours of direct fire exposure.
The Parameters of Foam Rolling, Self-Myofascial Release Treatment: A Review of the Literature
Authors: Dębski Przemysław , Białas Ewelina , Gnat Rafał 
Published: February 2019

Abstract
Self-myofascial release (SMR) is a well-known and popular therapy. Its growing popularity is based on high effectiveness and availability. However, there is a lack of agreement about which parameters should be used to optimize the effects of the therapy. The purpose of this review is to critically select and assess current literature and ascertain the values of the follow­ing parameters: (1) therapy duration, (2) volume of applied pressure, (3) speed and (4) frequency of roll, (5) type of roller, (6) the number of treatment applications during one session, (7) the duration of intervals between applications that yield the best results in terms of soft tissue.
The authors launched their research in May 2018. The search strategy included the electronic databases EBSCOhost and PubMed. The following inclusion criteria were assessed:
- English language, high quality manuscripts (evaluation in PEDro scale)
- at least one of the groups using the foam roller, tennis ball or the stick to fascial release
- basic parameters of therapy described.A total 55 articles met the inclusion criteria. Patients can usually withstand a maximum tolerable pressure for 30-120 seconds, repeated 1-3 times, separated by 30 seconds of rest. The intensity of a single rolling movement should be moderate, and the movement should last about 3 seconds. Keeping the roller on particularly sensitive areas is recommended to release tension and enhance blood perfusion.Currently, there is no consensus on an optimal FR programme. However, there is a tendency to use SMR tools with a physiol­ogy-based method to enhance therapeutic efficiency.
Different levels of physical activity and anthropometric profile in patients infected with hepatitis C virus
Authors: Simões Lucas de Lucena de , Lima Eline Autran de , Santos Gabriela Carvalho Jurema , Oliveira Tafnes , Bernardo Elenilson Maximino , Olegário Luana , Siqueira Erika Rabelo Fortes , Fernandes Matheus Santos de Sousa 
Published: February 2019

Abstract
Study aim: To verify the relationship between different durations of regular practice of physical activity in aspects related to the anthropometric profile and hepatic function of patients infected by hepatitis C virus (HCV). Material and methods: 125 patients (aged 55.2 ± 10.4 years) participated in the study. Clinical data were obtained through medical records available at the Pernambuco Liver Institute. Physical activity levels were obtained through the International Physical Activity Questionnaire (IPAQ) short form to classify the patients according to the guidelines of the American College of Sports Medicine (ACSM). Results: Significant differences were found in GGT 141 (28-378 U/L) and HDL 39 (27-56 mg/dL) respectively in insuffi­ciently active and physically active groups, AST 71 (26-268 U/L), ALT 83 (36-452 U/L), GGT 78 (3-532 U/L), alkaline phos­phatase 74 (47-302 mg/dL) and total bilirubin 0.7 (0.1-2.8 mg/dL) in insufficiently active and very physically active groups. Anthropometric data showed significant differences in chest (p < 0.01), abdomen (p < 0.02) and waist measurement (p < 0.01) between insufficiently active and very physically active groups.
Conclusion: Physical activity, when practiced regularly for more than 300 minutes per week, can improve the clinical and an­thropometric profile in patients infected with HCV.