bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extended Spectrum Beta-lactamase producing Salmonella Lindenberg gastroenteritis
Authors: Prabhurajan Rajan , Kiran Rajasekharapanicker , Padmavathy Kesavaram 
Published: October 2019

Introduction: Increasing antimicrobial resistance among non-typhoidal Salmonella (NTS) is a major public health issue especially in developing countries and is partly due to the use of antimicrobials in animal feeds as growth promoters. NTS are often associated with self-limiting acute gastroenteritis (AGE). Nevertheless, fluoroquinolones and third-generation cephalosporins are currently used in the treatment of severe diarrhoeal infections.
Methodology: We report the case of a 30-year-old male who presented with clinical symptoms of moderate gastroenteritis. Stool culture and antibiotic susceptibility was performed as per standard microbiological methods. Molecular detection of bla genes was carried out by PCR.
Results: The isolate was confirmed as S. Lindenberg by serotyping. The isolate exhibited dual resistance to fluoroquinolone and third generation cephalosporins. The isolate was an ESBL producer and harboured blaSHV. Based on the antibiotic susceptibility pattern, the patient was successfully treated with ceftriaxone-tazobactam.
Conclusion: Presently, there are no Indian reports on the blaSHV positive ESBL producing S. Lindenberg gastroenteritis. We report on the successful management of the first case of acute gastroenteritis caused by S. Lindenberg that exhibited dual resistance to fluoroquinolone and third generation cephalosporins. Continued surveillance of the antibiotic resistance pattern of the Non-typhoidal Salmonella serovars circulating in the geographical region is warranted.
Levels of different cytokines in women and men with asymptomatic genital infection caused by Chlamydia
Authors: Bua Alessandra , Cannas Sara , Zanetti Stefania , Molicotti Paola 
Published: October 2019

Introduction: Immune response to genital Chlamydia trachomatis infection is involved in both immunity and pathology. The cytokine profile during infection has been implicated in the disease outcome, either resolution or severe sequelae.
Methodology: In total, 3900 patients were analyzed for presence of genital infections caused by Chlamydia using molecular assays. Interleukins (IL) IL-10, IL-17, IL-6, IL-2 and chemokine IP-10 were estimated by ELISA in urine, cervical swabs and semen samples. Statistical analysis was performed using the T student test.
Results: A total of 47 out of 3900 samples (1.2%) were found to be positive for Chlamydia trachomatis based on the Real Time (RT) PCR results. Statistical analysis revealed that the differences between Chlamydia trachomatis positive and negative samples regarding levels of cytokines were not signiﬁcant.
Conclusions: Our results demonstrated that no signiﬁcant difference in cytokine concentrations exists in Chlamydia trachomatis infected patients when compared to healthy controls. In further study, we aim to test on a greater number of positive samples a greater number of cytokines involved in the immune response to Chlamydia trachomatis infections.
Digital learning ecologies and professional development of university professors
Authors: González-Sanmamed Mercedes , Estévez Iris , Souto-Seijo Alba , Muñoz-Carril Pablo-César 
Published: October 2019

This study analyses the extent to which faculty use the technological resources that make up their Learning Ecologies to encourage their teacher professional development. The interest of this research is the growing impact of Learning Ecologies as a framework to examine the multiple learning opportunities provided by the complex digital landscape. Global data referred to the use of technological resources grouped in three dimensions (Access, Search and Information Management resources, Creation and Content Editing resources, and Interaction and Communication resources) has been identified. In addition, the influence of different variables such as gender, age, years of teaching experience and the branch of knowledge were also examined. The methodology used has been quantitative through a survey. The sample consisted of 1,652 faculty belonging to 50 Spanish universities. To meet the aim of the study, descriptive and inferential analysis (ANOVA) were carried out. On the one hand, it is noted a moderate use of technological resources for professional development and, on the other hand, significant differences are observed on all variables analysed. The results warn of the need to promote, both at individual and institutional level, more enriched Learning Ecologies, in such a way that each teacher can take better advantage of the learning opportunities, provided by the networked society.
En este estudio se analiza en qué medida el profesorado universitario utiliza los recursos tecnológicos que configuran sus Ecologías de Aprendizaje para propiciar su desarrollo profesional como docentes. El interés de esta investigación radica en el creciente impacto del constructo de las Ecologías de Aprendizaje como marco para examinar e interpretar las múltiples oportunidades de aprendizaje que ofrece el complejo panorama digital actual. Además de identificar los datos globales referidos al uso de los recursos tecnológicos agrupados en tres dimensiones (recursos de acceso, búsqueda y gestión de la información, recursos de creación y edición de contenido, y recursos de interacción y comunicación), también se examina la influencia de diferentes variables como el género, la edad, los años de experiencia docente y la rama de conocimiento. La metodología empleada ha sido de corte cuantitativo a través de encuesta. La muestra está compuesta por 1.652 profesores pertenecientes a 50 universidades españolas. Para dar respuesta al objetivo del estudio se llevaron a cabo análisis descriptivos e inferenciales (ANOVA). Se constata un empleo moderado de los recursos tecnológicos para el desarrollo profesional y, además, se observan diferencias significativas en función de las variables analizadas. Los resultados alertan de la necesidad de fomentar, tanto a nivel individual como institucional, Ecologías de Aprendizaje más enriquecidas, de manera que cada docente pueda aprovechar mejor las posibilidades de aprendizaje que ofrece la sociedad en red.
Faire problématiser des élèves de CE2 en histoire à partir de témoignages
Authors: Doussot Sylvain , Fink Nadine 
Published: October 2019

La conception et la mise en œuvre d’une séquence (en CE2) portant sur la mémoire et l’histoire de la vie quotidienne au XX e est analysée sous le prisme de la potentialité didactique des témoignages pour développer la pensée critique des élèves par une démarche d’enquête. Les témoignages recueillis par les élèves sont confrontés entre eux et aux idées des élèves, pour mettre en rapport points de vue des témoins et des élèves, mais aussi mémoire individuelle et mémoire collective. Un processus de conceptualisation historique s’engage et on observe des difficultés à mener conjointement la critique de l’interprétation du passé et celle des sources.
Comparison of Efficacy of Conventional Nonmodified-Release Minocycline and Newer Extended-Release Minocycline in Treatment of Acne Vulgaris
Authors: Sardesai Vidyadhar R , Uttamani Ruhi R 
Published: October 2019

Aims:
The aim is to study the efficacy of conventional and extended-release minocycline therapy in acne vulgaris and to compare the two regimens for the efficacy and side effects.

Materials and Methods:
An open, randomized, comparative, prospective study was conducted on forty newly diagnosed cases of acne vulgaris (Grades 2 and 3) with more than 15 lesions. Patients were randomly allotted into one of the two groups which received extended-release minocycline and conventional minocycline, respectively, for 3 weeks. Both groups were prescribed local application of benzoyl peroxide 2.5% at night. All the patients were evaluated at the end of 3 weeks using paired and unpaired t-test.

Results:
Improvement was noted in patients belonging to both the groups. When both the groups were compared statistically using unpaired t-test, extended-release minocycline was significantly better in the treatment of inflammatory papules.

Conclusions:
Both conventional minocycline and extended-release minocycline were effective in the treatment of moderate and moderately severe acne vulgaris. Statistically inflammatory lesions respond better to extended-release minocycline.
Integration of Continuous Quality Improvement Methods Into Annual Program and Institutional Evaluation
Authors: Stansfield R. Brent , Markova Tsveti , Baker Richard 
Published: October 2019

ABSTRACT

Background
The Accreditation Council for Graduate Medical Education's Next Accreditation System requires continuous program improvement as part of program evaluation for residency training institutions and programs.

Objective
To improve the institutional- and program-level evaluation processes, to operationalize a culture of continuous quality improvement (CQI), and to increase the quality and achievement of action items, the Wayne State University Office of Graduate Medical Education (WSU GME) incorporated CQI elements into its program evaluation process.

Methods
Across 4 academic years, WSU GME phased the following 4 CQI elements into the evaluation process at the program and institutional levels, including the annual program evaluation (APE) and the annual institutional review: (1) An APE template; (2) SMART (specific, measurable, accountable, realistic, timely) format for program and institutional goals; (3) Dashboard program and institutional metrics; and (4) Plan-do-study-act cycles for each action item.

Results
Action item goals improved in adherence to the SMART format. In 2014, 38% (18 of 48) omitted at least 1 field, compared with 0% omitting any fields in 2018. More complete action items took less time to resolve: 1.7 years compared with 2.4 years (t(43.3) = 2.87, P = .003). The implementation of CQI in the APE was well received by program leadership.

Conclusions
After leveraging CQI methods, both descriptions of institutional- and program-level goals and the time required for their achievement improved, with overall program director and program coordinator satisfaction.
Are You Now or Have You Ever Been a Suvinian? Beyond the Moralizing Temptation; or, How Not to Read
Authors: Wegner Phillip E. 
Published: October 2019

ABSTRACT
This article begins as a response to a review recently published in Utopian Studies. It argues that the prescriptive forms of ethical criticism practiced in this review are symptomatic of more general trends in our scholarly communities. The article is modeled on Jacques Derrida's “Limited Inc a b c. …” In his essay, Derrida illustrates the ways that genres such as the review, reply, and response open up the temptation to not read and to slip into moralizing modes of ethical judgment. Following Derrida's lead, the response unfolds at once in terms of what J. L. Austin identifies as a constative and a performative utterance: In its contents, it addresses misrepresentations and unspoken “absolute presuppositions”; and in its form, it enacts some of the practices that would be necessary for a more productive, responsible, and generous—that is, utopian—way of performing our intellectual labors.
De redelijke verwachting ten aanzien van de rekenrente
Authors: van Dort R.M.J.T. , Groot E.S. 
Published: October 2019

De redelijke verwachting ten aanzien van de rekenrente
Bij het berekenen van toekomstschade als gevolg van letsel, komt het aan op de redelijke verwachting van alle relevante omstandigheden. De rekenrente is een van die omstandigheden. In deze bijdrage pleiten auteurs ervoor de rekenrente te laten aansluiten op de historische ontwikkelingen en actuele prognoses van de financiële markten, inmiddels en langdurig gekenmerkt door lage rendementen en sombere verwachtingen. Daardoor zou de rekenrente naar hun mening in ieder geval gedurende een deel van de schadelooptijd negatief moeten zijn. Auteurs adviseren voorts om een deskundigencommissie aan te stellen die periodiek adviseert omtrent de in redelijkheid te verdisconteren rekenrente bij toekomstschade.
On a new species of the genus Cyprinotus (Crustacea, Ostracoda) from a temporary wetland in New Caledonia (Pacific Ocean), with a reappraisal of the genus
Authors: Martens Koen , Yavuzatmaca Mehmet , Higuti Janet 
Published: October 2019

The New Caledonia archipelago is known for its high level of endemism in both faunal and floral groups. Thus far, only 12 species of non-marine ostracods have been reported. After three expeditions to the main island of the archipelago (Grande Terre), about four times as many species were found, about half of which are probably new. Here, we describe a new species, Cyprinotus drubea sp. nov., which is characterised mainly by the hyper-developed dorsal hump on the right valve, much larger than in any other known Recent species in this genus. After a literature study of the other presumed species in Cyprinotus Brady, 1886, we retain seven Recent species in the genus, including the present new species. Cyprinotus crenatus (Turner, 1893), C. dentatus (Sharpe, 1910), C. flavescens Brady, 1898, C. inconstans Furtos, 1936, C. newmexicoensis Ferguson, 1967, C. ohanopecoshensis Ferguson, 1966, C. pellucidus (Sharpe, 1897), C. scytodus (Dobbin, 1941) and C. sulphurous Blake, 1931 are here all referred to the genus Heterocypris s. lat. Claus, 1892. Cyprinotus unispinifera Furtos, 1936 is assigned to the genus Cypricercus Sars, 1895. Cyprinotus tenuis Henry, 1923, C. fuscus Henry, 1919 and C. carinatus (King, 1855) are here classified as doubtful species. A checklist of the 14 non-marine ostracods, now including Cyprinotus drubea sp. nov. and Cypris granulata (Daday, 1910), thus far reported from New Caledonia, is provided. Herpetocypris caledonica Méhes, 1939 and H. caledonica var. minor Méhes, 1939 are synonymised with Candonocypris novaezelandiae (Baird, 1843).
La nación costarricense y las poblaciones afrodescendientes: hacia la adopción del modelo multiculturalista.
Authors: Balutet Nicolas 
Published: October 2019

Desde hace más de 500 años, el subcontinente hispanoamericano ha conocido numerosas olas de migraciones procedentes de Europa, África, Medio Oriente o Asia. Aunque los migrantes voluntarios o forzados han contribuido a lo largo del tiempo a hacer de esta región del mundo un verdadero crisol de poblaciones ampliamente mestizadas, el sufrimiento original relacionado con el desarraigo y/o la esclavitud no ha desaparecido del todo porque los europeos y sus descendientes consiguieron imponerse a menudo a costa de otras poblaciones. Frente a estas situaciones de relegación e incluso de segregación que, a veces, no han desaparecido, los outsiders étnicos han adoptado estrategias para luchar activamente por el reconocimiento de sus derechos. Este artículo se propone estudiar la evolución de la situación de los afrodescendientes en Costa Rica.
For more than 500 years, the Spanish-American subcontinent has experienced many waves of migration from Europe, Africa, the Middle East or Asia. Although voluntary or forced migrants have contributed over time to make this part of the world a veritable melting pot of largely mixed populations, the original suffering of uprooting and/or enslavement has not been uniformly alleviated because Europeans and their descendants have often succeeded in imposing themselves at the expense of other populations. Faced with these situations of discrimination and even segregation, which haven’t all disappeared today, ethnic outsiders have adopted various strategies to actively fight for the recognition of their rights. This article aims to study the situation of African descendants in Costa Rica.
ORCID, RRID’s and Research Objects, Oh My!
Authors: De Waard Anita 
Published: October 2019

To support superior ways of sharing scientific, medical and engineering knowledge, Elsevier has been an active participant in a plethora of research projects, multi-stakeholder communities, alliances and data standards organisations. As an example, we will discuss how Elsevier has contributed to organisations that advocate and govern the use of unique identifiers throughout the scholarly lifecycle.
The shared use of unique identifiers for finding and linking to papers, authors, and institutions has been an area where Elsevier has invested in, from the beginning. After the resounding success of the Digital Object Identifier project, which lead to the foundation of CrossRef, a multi-stakeholder organisation that manages DOIs across the publishing landscape, Elsevier was one of the founders of ORCID, intended to assign unique identifiers to scientists.
Further cross-stakeholder initiatives for identifying objects to improve findability were pursued through Force11, a multi-stakeholder organisation to improve scholarly communication, which Elsevier staff helped co-found. The RRID project advocates and governs the use of identifiers for key research resources (such as antibodies and model animals) and the Data Citation Principles advocate a common model of sharing, citing and attributing datasets, based on DOIs for Datasets. These principles have been brought to bear inside the open Mendeley Data platform, where unique identifiers are assigned to datasets, and even versions of datasets, so that distinct iterations of a collection of research data can be cited and found.
Currently, Elsevier staff are collaborating with the University of Manchester to build a portal to generate identifiers for bioinformatics workflows, based on Manchester’s ‘Research Object’ specification. This will allow bioinformatics researchers to link their software, data inputs, outputs, and publications together in a single ‘Research Object’, which can be found, cited, and linked to publications.
Residual Effect of Different Sources of Nutrients on Available NPK in Soil after Harvest of Maize in Rice Fallow Maize Cropping System
Authors: Puli Mohana Rao , Prasad P. R. K. , Babu P. Ravindra , Rao K. L. Narasimha , Subbaiah G. 
Published: October 2019

A field experiment was conducted for two consecutive years (2011-2012 and 2012-2013) on fine texture soils of Agricultural college farm, Bapatla. The experiment was laid out in a randomized block design in kharif season with four treatments. The treatments consisted of M1 (RDF (Recommended dose of fertilizers) - Control), M2 (10t FYM (Farm Yard Manure) ha-1 + RDF), M3 (1.5t vermicompost ha-1 + RDF), M4 (Green manuring + RDF). During the immediate rabi, the experiment was laid out in a split-plot design without disturbing the soil for succeeding maize with the four treatments given to kharif rice as main plot treatments and each of these divided into five sub-plots to receive five levels of fertilizer NPK application viz., N1 - 75% NPK, N2 - 100% NPK, N3 - 125% NPK, N4 - 150% NPK and N5 - 175% NPK for succeeding maize.
Data collected on available NPK after harvest of maize crop were significantly increased with the application of 100% NPK in combination with FYM @10t ha-1 to preceding rice crop, irrespective of the NPK levels applied to succeeding maize crop. However, it was on par with that of green manuring together with 100% NPK during both the years of the study.
Physician Reasons for or Against Treatment Intensification in Patients With Metastatic Prostate Cancer
Authors: Agarwal Neeraj , George Daniel J. , Klaassen Zachary , Sandin Rickard , Butcher Jake , Ribbands Amanda , Gillespie-Akar Liane , Emir Birol , Russell David , Hong Agnes , Ramaswamy Krishnan , Freedland Stephen J. 
Published: December 2024

ImportanceClarifying the underutilization of treatment intensification (TI) for metastatic castration-sensitive prostate cancer (mCSPC) may improve implementation of evidence-based medicine and survival outcomes.ObjectiveTo investigate physicians’ beliefs about TI in mCSPC to understand the gap between evidence-based guidelines and clinical practice.Design, Setting, and ParticipantsThis survey study analyzed data from the Adelphi Real World retrospective survey, which comprised physician surveys that were linked to medical record reviews of US adult patients treated for mCSPC between July 2018 and January 2022.Main Outcomes and MeasuresThe survey included questions on physician and practice demographics. Physicians completed patient record forms, based on patient medical records with information including patient demographics, clinical characteristics, and patient management. Physicians recalled reasons for prescribing decisions using 48 precoded and open-text responses. Bivariate and multivariable analyses assessed the likelihood of their patients receiving first-line TI; the main outcome was the likelihood of their patients receiving TI using odds ratios (ORs).ResultsIn total, 617 male patients met the analysis criteria (mean [SD] age, 68.6 [8.1] years). Among these patients, 349 (56.6%) were Medicare beneficiaries. Overall, 430 (69.7%) did not receive first-line TI with androgen receptor pathway inhibitors and/or chemotherapy. The 107 US-based physicians’ top reasons for treatment choice for their patients were tolerability concerns (TI: 121 [64.7%]; no TI: 252 [58.6%]; P = .18) and following guideline recommendations (TI: 115 [61.5%]; no TI: 230 [53.5%]; P = .08). In the bivariate analysis, physicians seeking to reduce prostate-specific antigen (PSA) by 75% to 100% were more likely to provide first-line TI compared with physicians who aimed to lower PSA by 0% to 49% (OR, 1.63 [95% CI, 1.04-2.56]; P = .03). In the multivariable analysis, patients whose physicians based treatment choice on guidelines were more likely to receive TI than patients whose physicians did not report this reason (OR, 3.46 [95% CI, 1.32-9.08]; P = .01).Conclusions and RelevanceThe findings of this study, which analyzed data from a medical records–linked clinical practice survey, indicated low rates of first-line TI for mCSPC despite guideline recommendations. Barriers to TI included lack of knowledge about guidelines and published efficacy and safety data. Physicians with greater PSA reduction goals were more likely to use TI. Physician education on treatment guidelines and clinical trial data, while raising expectations for PSA response, may increase rates of first-line TI in mCSPC.
Q
‐Factor
Authors: Kajfez Darko 
Published: December 2024

Abstract

Radiofrequency (RF) and microwave resonators are characterized by their resonant frequency, coupling coefficient, and unloaded
Q
‐factor. Definition of the
Q
‐factor consists of a ratio of the stored energy and the dissipated power at resonant frequency. Distinction should be made between the unloaded, loaded, and external
Q
. The article provides some frequently used equations related to the application of
Q
‐factors. The measurement techniques for determining the
Q
‐factor can be classified as being of transmission type, reflection type, and reaction type. The measurement is typically performed with a vector network analyzer and a curve‐fitting procedure is applied to determine the loaded resonant frequency, the loaded
Q
, and the coupling coefficient. The measurement is redundant as many more data points are taken than the necessary minimum, so that it becomes possible to estimate the random uncertainty of the unloaded
Q
.