bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of cell-free fetal DNA on invasive prenatal diagnostic tests in a real-world public setting
Authors: Herraiz Ignacio , Villalba Ana , Ajuria Eliam , Barasoain Alba , Mendoza Ana , Pizarro Nazaret , Escribano David , Galindo Alberto 
Published: July 2019

Abstract

Objective
To evaluate the impact of cell-free fetal DNA (cfDNA) test on the number of invasive tests carried out in a public hospital that does not include this test in its services.

Methods
This was a retrospective cohort study in singleton pregnancies with a high risk (>1:270) on the first-trimester screening for aneuploidies. The options of performing an invasive test or a cfDNA test were explained to all women, the latter being especially recommended to those with a 1:50–1:270 risk (Group 1). If the risk was >1:50 (Group 2), or nuchal translucency (NT) was >99th percentile or there were major malformations (Group 3), invasive test was recommended.

Results
A total of 755 of 14,398 (5.2%) cases had a high-risk first-trimester screening, of whom 46 cases were excluded due to incomplete follow-up. In the remaining 709 cases, the percentage of aneuploidies was 9.9% (70 cases) and 110 opted for a cfDNA test (15.5%). There were two true-positive results of cfDNA (one in Group 2 and another in Group 3). In Group 1, 67.4% [95% confidence interval (CI) 60.0%–72.1%, P < 0.01] fewer invasive procedures were performed in those who opted for a cfDNA test, without having false negatives.

Conclusion
Pregnant women with a 1:50–1:270 risk who opt for cfDNA save two out of three invasive tests, without affecting the aneuploidy detection rate.
A Rising Tide that Lifts no Boats. The European Union and the Development of the Transnational Economy of Crimigration
Authors: Rewizorski Marek 
Published: July 2019

AbstractThe author of the article focuses on investigating the relationship between the outbreak of irregular migration to Europe and the increasing importance of transnational criminal networks. The starting point is the assumption that the transnational economy of crimigration (TEC) is driven by the illicit activity of private actors (the supply side) and potential migrants who create the demand for this kind of services, often not realizing the full extent of the consequences of entering into contractual relationships with groups of smugglers (the demand side). It is also assumed that the dynamics of the transnational economy of crimigration is one of the main causes of the rising wave of irregular migration and the migration crisis in the European Union.
Des Unternehmers «volkstümliche» Biographie, oder: wie die Ruhrkohlenindustrie Geschichte machte
Authors: Roelevink Eva-Maria 
Published: July 2019

Abstract:

A popular biography or: how the Ruhrcoal industry created history. The general assumption in our profession is that history it analyzed and written by qualified historians. Companies, industrialists and associations, however, are and were active in especially writing business history as well. It is evident that they commissioned commemorative publications for different reasons than historians wrote business history. By aiming to apply their business history frequently for political reasons of the present time, it turned out to be useful for them to hide the fact that the publications were commissioned working projects. By exemplifying the biography of Emil Kirdorf, written and published in 1936 by Walter Bacmeister, the article draws attention to the ambitions that motivated the industrialists to merchandise Emil Kirdorf's life during the 1930s.
Nem tudo está perdido: Arqueologia e histórias de vida na contextualização de objeto arqueológico do MAE/UFBA
Authors: Costa Carlos Alberto Santos 
Published: July 2019

Neste artigo utilizo a perspectiva das “histórias de vida” com o objetivo de contextualizar e indicar o provável local de coleta feita por moradores locais de uma urna funerária, posteriormente resgatada pelo arqueólogo Valentín Calderón nos anos 60 do século XX, no município de Morro do Chapéu, Bahia. Tomando como ponto de partida a minha história e as minhas memórias pessoais, identifiquei interlocutores que viveram este episódio e fiz o enlace das suas “histórias de vida” com dados arqueológicos e com informações salvaguardadas no Mae/Ufba. Este caminho percorrido permitiu a obtenção de elementos comuns das “histórias de vida” dos diferentes atores sociais para a criação de uma nova narrativa sobre o objeto arqueológico. Assim, é possível compreender melhor esse objeto, então sob a salvaguarda do museu, e indicar caminhos futuros para novas pesquisas.

Abstract: In this article I use the perspective of “life histories” with the purpose of contextualizing and indicating the probable place of collection by local residents of a funeral urn, later rescued by the archaeologist Valentín Calderón in the 60s of the 20th century, in the municipality of Morro do Chapéu, Bahia. Taking as my starting point my story and my personal memories, I identified interlocutors who lived through this episode and linked their “life histories” with archaeological data and information safeguarded in Mae/Ufba. This path allowed me to obtain common elements of the “life histories” of the different social actors for the creation of a new narrative about the archaeological object. Thus, it is possible to better understand this object under the safeguard of the museum and indicate future paths for further research.
Reflexões sobre experiências de racismo institucional e ambiental de comunidades remanescentes de quilombos do Recôncavo da Bahia.
Authors: De Carvalho Ana Paula Comin 
Published: July 2019

O artigo procura fazer algumas considerações sobre as experiências de racismo institucional e ambiental vivenciadas pelas comunidades remanescentes de quilombo do Recôncavo da Bahia e seus reflexos sobre o acesso desses grupos a bens, serviços sociais e a assunção da cidadania plena. Para tal, realizamos uma etnografia sobre os conflitos vivenciados nos processos de regularização territorial dessas coletividades tendo por base nossa experiência de pesquisa na região, dados oficiais, investigações acadêmicas, notícias de jornais, dentre outras fontes. A análise de casos exemplares revela que apesar da existência de leis e políticas afirmativas voltadas para a questão, prevalecem os interesses de grandes proprietários de terras e empreendimentos privados de interesse estatal configurando um ciclo cumulativo de danos e prejuízos a esses grupos. Abstract: The article tries to make some considerations about the experiences of institutional and environmental racism experienced by the quilombo remnant communities of the Recôncavo of Bahia and its reflections on the access of these groups to goods, social services and the assumption of full citizenship. To this end, we conducted an ethnography on the conflicts experienced in the processes of territorial regularization of these collectivities, based on our experience of research in the region, official data, academic investigations, news from newspapers, among other sources. The analysis of exemplary cases reveals that despite the existence of affirmative laws and policies focused on the issue, the interests of large landowners and private enterprises of state interest prevail, setting a cumulative cycle of damages and losses to these groups.
Memórias da (des)territorialização indígena: A colonização como centro irradiador das vilas
Authors: Pereira Túlio Henrique , Souza Ramon Queiroz 
Published: July 2019

Ao tomarmos como objetos de análise a pintura A primeira missa no Brasil, de Victor Meirelles, e a planta da Vila de Abrantes, produzida pelo capitão Domingos Alves Branco Muniz Barreto, sobre o território indígena do sertão baiano, objetivamos compreender algumas das memórias da desterritorialização das terras indígenas e as transformações do espaço natural do território brasileiro a partir do contato estabelecido entre portugueses e indígenas no período colonial. Na análise, refletimos sobre como a apropriação do espaço, antes pertencente aos indígenas, se deu acompanhada de símbolos do poder. Neste artigo, pensamos na transformação do espaço natural convertido em símbolo do poder europeu, evidenciando conflitos e reestruturações de significados do território do sertão baiano a partir do século XV. Abstract: By taking as subject of analysis the painting A primeira missa no Brasil (The first mass in Brazil) by Victor Meirelles and the plans of Vila de Abrantes (Abrantes Villa) designed by Captain Domingos Alves Branco Muniz Barreto, regarding the indigenous territory of the Bahian’s backland, we aim in this work to understand some of the memories of the deterritorialization of indigenous lands and the transformations of the Brazilian territory natural space since the contact established between Portuguese people and indigenous people in the Colonial Period. In the analysis, we reflect on how the appropriation of the territory happened alongside the use of symbols of power. In this paper, we think about the transformation of the natural space converted in a European symbol of power, revealing conflicts and meaning restructure of the Bahian backland territory from the XV century on.
Cartografia subjetiva em território feminino kilombola: em busca da utopia do bem viver
Authors: Labrea Valéria Viana , Kiekow Pedro Eduardo , Dornelles Denise Freitas 
Published: July 2019

Este artigo traz resultados iniciais do projeto de pesquisa e extensão universitária Pedagogia do Encantamento e Ekonomia do Afeto: Cartografia Subjetiva em Território Feminino Kilombola. Apresentaremos especificamente um primeiro nível deste mapa, uma parte da história da Comunidade e seus moradores, organizada a partir das narrativas dos pesquisadores e pesquisadoras e dos outros moradores do kilombo. Abstract: This article bring initial results of reserch and extension projetc of university Pedagogy of Enchantment and Ekonomics of Affection: Subjective Cartography in Female Territory Kilombola. We will present specifically a first level of this map, a part of the history of the Community and its inhabitants, organized from the narratives of the researchers and the other inhabitants of the kilombo.
TNF-α Differentially Regulates Cell Cycle Genes in Promyelocytic and Granulocytic HL-60/S4 Cells
Authors: Jacobson Elsie C , Jain Lekha , Vickers Mark H , Olins Ada L , Olins Donald E , Perry Jo K , O’Sullivan Justin M 
Published: July 2019

AbstractTumor necrosis factor alpha (TNF-α) is a potent cytokine involved in systemic inflammation and immune modulation. Signaling responses that involve TNF-α are context dependent and capable of stimulating pathways promoting both cell death and survival. TNF-α treatment has been investigated as part of a combined therapy for acute myeloid leukemia due to its modifying effects on all-trans retinoic acid (ATRA) mediated differentiation into granulocytes. To investigate the interaction between cellular differentiation and TNF-α, we performed RNA-sequencing on two forms of the human HL-60/S4 promyelocytic leukemia cell line treated with TNF-α. The ATRA-differentiated granulocytic form of HL-60/S4 cells had an enhanced transcriptional response to TNF-α treatment compared to the undifferentiated promyelocytes. The observed TNF-α responses included differential expression of cell cycle gene sets, which were generally upregulated in TNF-α treated promyelocytes, and downregulated in TNF-α treated granulocytes. This is consistent with TNF-α induced cell cycle repression in granulocytes and cell cycle progression in promyelocytes. Moreover, we found evidence that TNF-α treatment of granulocytes shifts the transcriptome toward that of a macrophage. We conclude that TNF-α treatment promotes a divergent transcriptional program in promyelocytes and granulocytes. TNF-α promotes cell cycle associated gene expression in promyelocytes. In contrast, TNF-α stimulated granulocytes have reduced cell cycle gene expression, and a macrophage-like transcriptional program.
Propuesta metodológica para la formación de guías naturalistas locales
Authors: González Ángela 
Published: July 2019

Se da cuenta de un trabajo de campo de un año y ocho meses (2003-2004) realizado en la comunidad Siberia (sur de San José, Costa Rica) consistente en preparar e impartir un curso para formar 23 miembros de la comunidad como guías naturalistas locales. La experiencia sirvió de base para realizar una propuesta metodológica con el fin de formar guías locales en contextos similares. Los resultados, que aquí se explicitan, se enfocaron a responder a las preguntas: ¿dónde enseñar?, ¿a quién enseñar?, ¿qué enseñar?, ¿cómo enseñar? y ¿cómo evaluar el aprendizaje? La metodología empleada permitió que los participantes adquirieran conocimientos y habilidades para desempeñarse adecuadamente como guías naturalistas locales y generó en ellos cambios sobre la visión y el modo de relacionarse con la naturaleza.
Comparison of the efficacy of two types of hemodialysis catheters: the VectorFlow vs. Palindrome catheters
Authors: Ali Veisi , MohammadReza Sobhiyeh 
Published: July 2019

Introduction: Permanent vascular access via catheters is a critical factor for patients who need long-term hemodialysis. Differences in the design and mechanical factors can affect efficacy and survival of the permanent catheters. Modifications in the designs of the catheters can decrease the likelihood of damaging blood vessels as well as thrombosis formation and malfunction of the catheters.
Objective: To compare survival of VectorFlow, complete symmetry of distal tip and offsetting of its side holes, with those of Palindrome, a complete symmetrical catheter.
Methods: In this study, 146 CKD (chronic kidney disease) patients who required chronic hemodialysis were divided into VectrFlow (76 subjects) and Palindrome (70 subjects) catheter groups. The patients were followed for six months and the survival rate in each group was determined.
Results: Mean (+/-SD) survival time in the VectorFlow catheter group (6.55+/-3.88 months, 2 to 24 months) was longer than in the Palindrome catheter group (5.22+/-2.88 months, one to 13 months). After six months, the VectorFlow catheter group (40 cases, 54.8%) had a higher number of patients, having a functioning catheter in place than the Palindrome group (26 cases, 382%); P= 0.04.
Conclusion: The VectorFlow hemodialysis catheter had a better survival rate after 6 months when compared to the Palindrome catheter. We recommend using this catheter in CKD patients, who require a long-term permanent catheter.
AUDIOVISUAL MEANS IN THE PROCESS OF TEACHING RUSSIAN LANGUAGE AS FOREIGN LANGUAGE
Authors: Zaiets Anna Viktorovna 
Published: July 2019

The purpose of the research is elucidation of audiovisual media in the process of teaching Russian language as a foreign language. The task of the work is to study the existing types of audiovisual means of training; analysis of the possibilities of using audiovisual means as a modern type of training. The object of the research is audiovisual media, through which while learning of the Russian language as a foreign language appropriate mastering of the material is carried out. Descriptive method and method of analysis of intelligence information are used. As a result of the research, the main methodological aspects of work with audiovisual means of education on Russian as foreign language lessons were highlighted. Conclusions: 1. The key stages of the work are chosen according to the scheme «task – viewing a film – task». 2. The task before watching a movie involves analyzing information about the movie. 3. The tasks after watching a movie include exercises on understanding of the content, as well as the consolidation and introduction of the new vocabulary in the broadcast. 4. The broadcast of feature films has both an emotional effect, and serves as an impetus for activating an additional stimulus in the next educational, practical, and creative activity. The analysis made it possible for us to determine that the film's review must include the appropriate purpose, everyday situations, clear dialogues, in which repetitive words and phrases that occur on the film repeatedly help to better remember the new vocabulary and as a result – the development of speech activity students The ability to compare read and seen causes excessive interest of students and activates them into cognitive activity. The feature film is not a universal admission, but it has certain prerogatives: it provides work of educational value, which helps in the process of intensive language proficiency; suppresses the psychological potential of the student (development of attention, memory, thinking); promotes the interconnection of various types of speech activity; takes into account peculiarities of language usage in various stylistic aspects, etc.
CATEGORY OF FUTURALITY WITHIN THE SYSTEM OF MODUS CATEGORIES
Authors: Kirkovs’ka Inga 
Published: July 2019

The aim of the investigation under consideration is to study the nature of the category of futurality within the system of modus categories in the French language. The object of the work is the category of futurality in contemporary French, the subject is the study of the category of futurality in contemporary French within the system of modus categories of evidentiality, modality and persuasiveness. In the course of the study, the distinctions between modality and modus have been outlined, the place of the category of futurality within the modus categories has been identified, the peculiarity of the category of futurality as a modus category has been analysed. Conclusions: the peculiarity of futurality as a modus category is that it belongs to the modus categories denoting action/event, real in the future “in the speaker’s view”. In this sense the category of futurality is closer to the categories of modality (real information stated by the speaker) and predicativity (confidence in the information stated by the speaker) in meaning, whereas differing from them by the semantics of the stated temporality denoting the relation of consequence in reference to the moment of speaking. The category of futurality is connected with other modus categories: category of assertion with semantics of neutral prospection, category of persuasiveness with the seme of assurance in reference to the future and category of modality with the seme of reality in reference to the future. The major types of modal meanings forming the modus category of futurality are: 1) speaker’s estimation of the subject matter of the utterance from the perspective of reality/irreality in the future; 2) estimation of the environment of the utterance from the perspective of probability/necessity/desirability in the future; 3) speaker’s estimation of the level of assurance (persuasiveness) of the subject matter of the utterance from the perspective of the future; 4) communicative function of the utterance defined by the purpose of the speaker from the perspective of the future (wish, intention, preference); 5) confirmation/negation of objective relations between objects, phenomena, events of the future.
HIERARCHY OF COMMUNICATIVE UNITS IN RUSSIAN-LANGUAGE TEXTS
Authors: Menshikov Igor 
Published: July 2019

Objective of the study is to identify the hierarchical relations between communicative units that fill the Russian-language text. The object of study is the hierarchy as the sequential inclusion of some syntactic units into the other, more complex ones, the subject is Russian-language texts with syntactic constructions of various rank of hierarchies. The material of the study is twenty Russian-language texts containing communicative units which are built according to different models. Methods – descriptive, structural and quantitative methods were used. Findings: the sequence of occurrence in the text of predicative formations of varying complexity was revealed. Practical value – is possible in studies of the organization of the text as a syntactic unit. The realities of the language, as is well known, far from always can correspond to canonized judgments, interpretations and formulations, including those stated in official scientific, educational and reference editions. In a super-phrasal unity, there may not be complex sentences, and not only a super-phrasal unity or a complex sentence can function as a text as a syntactic unit, but a sentence can be simple and even a separate word, which can also be a communicative unit under certain conditions. Results: 1) the components of the text are predicative communicative units; 2) the formally expected vector of the hierarchy of communicative units should presumably have the following form: a simple sentence – a complex sentence – a superphrase unity – a text; 3) communicative units of the subsequent hierarchical rank due to their anti-transitivity are not always built directly from the units of the previous and preceding rank; 4) the order of location of the communicative units of different hierarchical levels, that fill the text is not strictly regulated and can be almost spontaneous, with multiple duplication of the same models.
LEXICAL AND GRAMMATICAL FEATURES OF FINAL ETIQUETTE FORMULAS IN RUSSIAN LETTERS OF THE XVIII CENTURY
Authors: Podoprigora Anastasija 
Published: July 2019

The purpose of the study is to define the lexical and grammatical features of the final etiquette formulas in Russian letters of the 18th century, to describe the functional and semantic types of formulas, to characterize their syntactic structure. The object of study is letters addressed to different persons by the outstanding Russian commander A. V. Suvorov and Princess E. R. Dashkova. The research material is 120 enclosed etiquette formulas extracted from letters with a continuous sampling method. The descriptive method of research has been used in the article. Practical application is possible in the process of teaching the stylistics of the Russian language. Conclusions: The final etiquette formulas are an important structural element of the ending of a letter, usually preceding the signature of the addressee. We have identified the following functional-semantic types of final etiquette formulas in Russian letters of the 18th century: 1) formulas of forgiveness; 2) formulas of wishes (wishes of physical and mental health, God's help and blessing); 3) parakinesthetic final etiquette formulas (verbal transmission of a gesture or an action); 4) honorific final etiquette formulas (direct or indirect indication by the addressor the addressee's positive qualities). The basis of the construction of the final etiquette formulas often lies in one or another speech cliche, however these cliches are spread by dependent syntactic components, as a result of which the final etiquette formulas in the letters under study are diverse in their syntactic structure. The perspective of the present study is in the research of the dynamics of the final etiquette formulas of writing in the epistolary of the 18th – 20th centuries, as well as in a more detailed explanation of the pragmatics and functioning of the etiquette formulas depending on the nature of the communicative situation.