bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cáncer bucal: conocimientos, actitudes y prácticas de los usuarios de la facultad de odontología de la Universidad de Antioquia, 2016
Authors: Botero Daniela , Gallego Katerin , Gutiérrez Ana María , Quintero Marcela , Ramirez Melissa , Posada-López Adriana 
Published: April 2019

Introducción: este artículo describe los conocimientos, actitudes y prácticas de los usuarios de la Facultad de Odontología de la Universidad de Antioquia acerca del cáncer bucal. Método: Se realizó un estudio con enfoque cuantitativo, descriptivo, se diseñó un instrumento de recolección donde se indagó por variables sociodemográficas además, se evaluaron los conocimientos, actitudes y prácticas de usuarios de la facultad de odontología de la universidad de Antioquia. Resultados y discusión: La mayoría de las personas encuestadas expresa tener conocimiento acerca de la presencia del cáncer en boca, pero que aunque reconocen su presencia no tienen conocimiento de cuáles son los signos de alarma del cáncer de boca y como de cómo puede prevenirlo, resultados que no varían en personas que son atendidas en la facultad y lo que no han recibido atención. A pesar de estos resultados gran parte de los encuestados se evalúa intrabucalmente, aunque no tenga instrucciones claras de cómo debe hacerlo. Conclusiones: el hecho de que las personas desconozcan como deben actuar frente al cáncer de boca a pesar de reconocer su existencia, está relacionado en gran medida con los profesionales de la salud, ya que la mayoría de los encuestados recibían atención en la facultad de odontología e incluso en otro centros de salud y aun así sus conocimientos, actitudes y practicas no variaban en gran medida con las personas que no tenían acceso a estos programas, por lo tanto se sugiere implementar una estrategia educativa que pueda aumentar el conocimiento de detección y prevención de cáncer de boca donde el odontólogo sea el actor principal.
Area Modification in Constructed Public Buildings in An Adaptive Reuse Perspective Former Presidency of Mosul University as a Case study
Authors: Abdullah Firas , Al-Allaf Emad 
Published: April 2019

The construction sector has recently rehabilitated and adapted a large number of buildings designed to meet the humanitarian needs and provide space required for various activities and services, that achieve the objectives of economic, cultural, technical and demographic changes. The Adaptive Reuse is one of the vital methods to provide buildings, due to their economic advantages in saving energy, resources, efforts and costs by maintaining constructed buildings. The paper discusses the importance of the constructed buildings and their physical and moral values​​, which determine the economic feasibility to prolong the building life. It also clarifies the contradictory relationship between building functional and structural age, beside t he internal and external challenges faced by buildings which represented by changes in space requirements, as well as physical, technical, social and economic changes. It deals with the adaptive reuse concept as a mechanism for retaining the socially required buildings, then determining the elements of this technique, applying what was drawn on a case study - a public construction (the previous presidency building of the Mosul University) which has been emptied of its function to occupy a new one (a guesthouse for the campus), measuring the efficiency of alternatives design, and determining the economic optimization based on the possibilities of spatial modification within adaptive principles and flexible design ideas. Following by presenting a set of recommendations to adopt in reusing process for altering the characteristics of an abandoned building by changing its function. The study analyzed the proposed building, its design and construction characteristics, evaluated them according to the principles of flexible design ideas as effective factors in adapting the building to the new use. Then, it presented a set of design alternatives that were implemented according to adaptability strategies, and next performing a comparison on the economic and functional characteristics - with neutralizing the aesthetic values - which are carried by each of these alternatives, which achieving the functional program derived from the analysis of a set of international models of university guesthouses, especially those meeting the local needs, followed by realizing the comparisons results, conclusions and recommendations for the project.
POSSIBILITIES OF APPLYING MATHEMATICAL ANALYSIS OF BLOOD FLOW CHARACTERISTICS IN ENDOVASCULAR TREATMENT OF AORTIC DISEASES USING HOLOMETALLIC STENTS
Authors: Chernyavskiy M. A. , Artyushin B. S. , Chernov A. V. , Chernova D. V. , Zherdev N. N. , Kudaev Yu. A. 
Published: April 2019

Purpose. The purpose of the article is to access possibilities of blood flow mathematical analysis in aortic aneurysm before and after bare metal stent implantation.Materials and methods. Mathematical models of aortic blood flow were based on data received at studying 15 CT-scans of patients with abdominal aorta aneurysms (12) and dissections (3) and their duplex ultra-sound hemodynamic data. At constructing mathematical model the program SolidWorks was used. Working with the program consisted of two stages: establishment of conditions for geometric objects; forming of abdominal aorta model from these objects. In the study hemodinamic aneurysm indexes was evaluated on rectilinear and curvilinear segments. Some of characteristics were variable: diameter, aneurysm wall thickness, its length, elasticity.Results. Correlation of extreme tension into aneurysm wall on rectilinear and curvilinear segments according to aneu­rysm wall thickness was assessed. Possibilities of pathological blood flow changes correction at bare metal stent im­plantation into aortic aneurysm were estimated: if presence of bare metal stent were introduced into mathematical parameters blood flow characteristics became almost as standard characteristics. Received data can enhance successful endovascular treatment of aortic diseases with using of bare metal stents.Conclusion. Mathematical models of aortic and vascular aneurysms before and after surgery can be an effective tool in bettering quality of medical help for vascular patients.
MULTIPLE SURGICAL TREATMENT OF A FEMALE PATIENT WITH RECURRENT PELVIC TERATOMA
Authors: Moshurov I. P. , Golovkov D. A. , Petrov L. O. , Sukhoverkov D. V. , Bykovtsev M. B. , Ryabkov N. S. 
Published: April 2019

Teratoma is a tumor consisting of several types of tissues derived from one, two or three germ leaves, the presence of which is not peculiar to those organs and anatomical areas of the body in which the tumor develops. According to the WHO classification definition, immature teratomas are those containing embryonic tissues along with definitive, mature tissue structures. In histological WHO classification immature teratomas belong to germ cell ovarian tumors and are in­cluded into the group of teracomas. The prognosis is determined by the variant of the histological structure, the primary localization of the tumor, timely and adequate treatment.This article presents a clinical case of treatment of a young female patient with persistently recurrent pelvic teratoma.The presented observation demonstrates, on the one hand, the unpredictability of the course of the tumor process in embryonic tumors. On the other hand, there were demonstrated the possibilities of surgical treatment of another re­lapse of teratoma in a young patient with a massive tumor of the pelvic cavity in a situation where the hopes for a radical operation according to previous abdominal revisions seemed vague.
Structural and Functional Characteristics of the Liver Under the Effect of Different Doses of Sodium Tetraborate
Authors: Berdalinova A. K. , Umbetov T. Zh. , Shevlyuk N. N. , Zhurabekova G. A. 
Published: April 2019

The aim of the study was to clarify the morphological and functional changes in the liver under the effect of sodium tetraborate.Material and methods. Morphological and functional characteristics of the liver of white outbred rats under single and long-term exposure to sodium tetraborate were studied using histological, histochemical, immunocytochemical and morphometric methods. Experimental animals were divided into 2 groups. Animals of the first group once intragastrically administered sodium tetraborate at a dose of LD50, animals of the second group daily for a month administered sodium tetraborate at a dose of 1/10 LD50. Animals of the first group were removed from the experiment a day after the introduction of sodium tetraborate, animals of the second group – 7, 14, 21 and 30 days after the start of the experiment.Results. Both single and long-term exposure to sodium tetraborate in the liver lobules marked multiple focal death of hepatocytes, microcirculation, bile stagnation in the biliary tract. The degree of damage and death of hepatocytes increases from the periphery to the center of the lobule. With prolonged exposure to sodium tetraborate in the first half of the experiment, stagnation of the blood elements in the capillaries was rare, and with an increase in the duration of the experiment (from 7 to 30 days), the proportion of intra-lobular sinusoid capillaries with stagnation of the shaped elements in them increased and more than half of the capillaries showed stagnation of the blood elements in them. Destructive changes in the liver were more pronounced when exposed to sodium tetraborate at a dose of LD50.Conclusion. In the conditions of low concentrations of sodium tetraborate in the liver, both destructive processes and transformations aimed at compensating for damage occur. With an increase in the dose of sodium tetraborate, the adaptive capabilities of the organ are exhausted and do not compensate for the damage to the cell structures of the organ.
Morphological Manifestations of Human Locomotor Bipedality in Femur
Authors: Yashina I. N. , Ivanov A. V. , Klochkova S. V. 
Published: April 2019

The aimis to study the structure of the femur of conditionally healthy modern people, as part of the link of the musculoskeletal system, providing bipedal locomotion.Material and methods.By the original osteometric method was measured 23 structures of 166 femoral bones with full synostosis of epiphysis without evidence of bone pathology. After the introduction of the coefficient of proportionality for linear parameters and the calculation of confidence intervals for each of them, a multilevel factor analysis was carried out, separately for the right and left femoral bones by the maximum likelihood factor analysis method with Equamax normalized rotation.Results.Four levels of the structural organization, which characterized by asymmetry of factor loadings, are identified. The parameters forming the 1st level ensure the transfer of the mechanical load along the limb axis from the head through the intertrochantcric crest to the medial condyle. 2nd level parameters provide rotational movements at the knee joint. Parameters of the 3rd and 4th levels reflecting the function of the rotation of the leg in the hip joint when upright and maintaining the vertical position of the body in the sagittal plane.Conclusion.Thus, the human femur is a multilevel system with asymmetric participation of parameters in its formation. Femur, as part of the musculoskeletal system, has a distinct vertical structural differentiation, which is manifested in the dominance of the right limb in the implementation of the support functions at the level of the proximal epiphysis, and motor functions at the level of the distal epiphysis of the femur.
Estructura espacial de los centros financieros offshore en Europa
Authors: Cela Juan Carlos Fernández 
Published: April 2019

Se ha analizado para toda Europa la red espacial de conexiones societarias internacionales filtradas en los denominados papeles de Panamá. Esto ha permitido conocer la morfología espacial de la estructura financiera de evasión de capital desde Europa a paraísos fiscales de todo el mundo. También permite elaborar una cartografía de flujos de capital financiero en Europa que identifica sus puntos de origen, tránsito y destino. El resultado revela la existencia de diferentes espacios financieros en el interior del continente, así como territorios fuera de Europa que se encuentran bajo el control geopolítico de la UE, y que constituyen nodos críticos como destino final del capital. El más importante con diferencia pertenece a los restos del imperio colonial inglés. Se trata de un espacio utilizado por Reino Unido para establecer una red financiera mundial que tiene su epicentro en la City y su destino final en las Islas Vírgenes Británicas.
Wernicke’s encephalopathy in a patient with severe acute pancreatitis after cholecystectomy and exploration of biliary tract
Authors: Du Huihui , Lei Xiaohua , Liu Qiang , Xu Xundi 
Published: April 2019

Abstract
Background

Wernicke’s encephalopathy (WE) is a disease classically associated with thiamine deficiency,and generally presents with the triad of opthalmopathy, ataxia and altered mentality. However, and delayed diagnosis and treatment may lead to severe irreversible neurological damage, or even death. Only about 20% of the cases can be defined from the relevant literature, with the rest unnoticed and thus unreported. Here, we would like to report a case of a patient with severe acute pancreatitis who suffered from Wernicke’s encephalopathy after cholecystectomy and exploratory of biliary tract.

Case presentation

A 37-year-old Chinese male patient diagnosed with severe acute pancreatitis was admitted to our institute’s hospital for further treatment. The patient had a 50-days history of abdominal pain as well as 8-days emesis, and wasn’t addicted in alcohol consumption. He did not receive any regular physical examination or treatment. One months before cholecystectomy and exploratory of biliary tract,he was noted to have abdominal pain, poor appetite, emesis and sclera icterus .He was referred to the local hospital, received supportive treatment, including antibiotics and liver-protection drugs . However, he got worse after those treatment,so transferred from the local hospital to our hospital for further therapy.. After operationhe was admitted in general ward for further treatment. When his vital signs and laboratory examination came to stability. He recovered well with supportive treatments, including antibiotics, liver-protection, protecting gastric mucosa and so on. However,his oral intake was low, and he was solely dependent on total parenteral nutrition without vitamin B1. On the 7th post-operative day, psychiatric and neurological disorders appeared without an obvious cause, symptoms including babbling, irritability, apathy, non-purposeful movements, and dystaxia. On the basic of his clinical manifestations and brain magnetic resonance imaging scan results, Wernicke encephalopathy was eventully diagnosed.

Conclusions

Although extremely rare, this index patient highlights that Wernicke’s encephalopathy could be associated with severe acute pancreatitis. This is very helpful for the therapeutic implications and evaluating curative effect. A multivitamin and thiamine should be provided for patients who have a surgery of cholecystectomy and exploratory of biliary tract so as to prevent and cure Wernicke’s encephalopathy.
Yangın Stratejilerinin Oluşturulması İçin İstatistik Veri Türlerinin Türkiye (İstanbul İli Örneğinde) ve Seçilmiş Ülkeler ile Karşılaştırılması
Authors: Bakırcı Erhan , KARATOP Buket , Bayındır Sümeyye 
Published: April 2019

Doğal ve insan kaynaklı afetler sonrasında
meydana gelen yangınlar ve yarattığı kayıpların toplum üzerinde travmatik
sonuçlar yarattığı bilinmektedir. Afetlerin yaratacağı zararların en az olması,
risklerin önceden belirlenmesine ve böylece afet sonuçlarının yönetilebilir
olmasına bağlıdır. Afetler ve özellikle yangın afetlerinin toplum üzerinde
oluşturduğu maddi manevi kayıplar ile sosyo-kültürel travmaların yanında eko
sistemdeki müthiş etkileri her gün biraz daha hissedilmektedir. Bundan dolayı
özellikle yangın güvenliği konusunda toplumsal bilinci yüksek, teknoloji üretip
satan veya bu konuda standartları oluşturan ülkelerde yangın istatistiklerinin stratejilerini
belirlemeye yardımcı olacak nitelikte tutulduğu ve kullanıldığı söylenebilir.
Bu güvenlikli ilişkiler zincirinin güçlü olması öğrenen sistemlerin kurulması
ile mümkündür. Tüm unsurların ölçülebilir-değerlendirilebilir ve ders alınıp
geliştirilebilir veri sisteminin oluşturulması ve kurulmasında temel faktör
sağlam, bilimsel ve hedefe dönük istatistik veri havuzu kurulması ve
farkındalık oluşturulmasıdır. Bu çalışmada, 2008 ve 2018 yılları arasında
İstanbul’da meydana gelen yangınlara ait istatistikler ile ABD, Çin ve AB
ülkelerinin yangın istatistikleri karşılaştırılmıştır. Karşılaştırılan
ülkelerle Türkiye’de İstanbul ili özelinde tutulan yangın istatistikleri
arasındaki veri tipleri incelenmiş bu çerçevede tespit edilen farklıklar
belirlenmiştir. Böylece tutulan
verilerin bilimsel çalışmalar ve önleyici yaklaşımla bu konuda stratejiler
oluşturmaya elverişli olup olmadığı tartışılmış ve iyileştirilmesi hususunda
öneriler sunulmuştur.
A decision support system for indirect potable reuse based on integrated modeling and futurecasting
Authors: Lodhi A. G. , Godrej A. N. , Sen D. , Angelotti R. , Brooks M. 
Published: April 2019

Abstract
Optimal operation of water reclamation facilities (WRFs) is critical for an indirect potable reuse (IPR) system, especially when the reclaimed water constitutes a major portion of the safe yield, as in the case of the Occoquan Reservoir located in Northern Virginia. This paper presents how a reservoir model is used for predicting future reservoir conditions based on the weather and streamflow forecasts obtained from the Climate Forecast System and the National Water Model. The resulting model predictions provide valuable feedback to the operators for correctly targeting the effluent nitrates using plant operations and optimization model called IViewOps (Intelligent View of Operations). The integrated models are run through URUNME, a newly developed integrated modeling software, and form a decision support system (DSS). The system captures the dynamic transformations in the nutrient loadings in the streams, withdrawals by the water treatment plant, WRF effluent flows, and the plant operations to manage nutrient levels based on the nitrate assimilative capacity of the reservoir. The DSS can provide multiple stakeholders with a holistic view for design, planning, risk assessments, and potential improvements in various components of the water supply chain, not just in the Occoquan but also in any reservoir augmentation-type IPR system.
Adsorption of cadmium and lead in wastewater by four kinds of biomass xanthates
Authors: Li Wunan , Liao Xiaoyong , Wang Lingqing , Huang Zhanbin 
Published: April 2019

Abstract
This study determined the adsorption of Cd2+ and Pb2+ (100 mg·L−1 of each) in simulated wastewater by biomass xanthates made from starch, chitosan, wheat stalk and corn stalk. The results showed that the adsorption efficiency of Pb2+ and Cd2+ ions followed the order: corn stalk xanthate &gt; wheat stalk xanthate ≥ chitosan xanthate &gt; starch xanthate. The results of kinetic modeling showed that the adsorption process was characterized by physical-chemical adsorption, and that a second-order kinetics equation described the adsorption process well. The optimum conditions for the adsorption of Cd2+ and Pb2+ by corn stalk xanthate were: adsorption time 2 hours, temperature 20–25 °C, and pH 6–8. The results serve as a reference for treating wastewater containing Cd2+ and Pb2+.
Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments
Authors: Magli Elisa , Corvino Angela , Fiorino Ferdinando , Frecentese Francesco , Perissutti Elisa , Saccone Irene , Santagada Vincenzo , Caliendo Giuseppe , Severino Beatrice 
Published: April 2019

Background:Sphingosine kinases (SphKs) catalyze the phosphorylation of sphingosine to form the bioactive sphingolipid metabolite sphingosine-1-phosphate (S1P). S1P is an important lipid mediator with a wide range of biological functions; it is also involved in a variety of diseases such as inflammatory diseases, Alzheimer’s disease and cancer.Methods:This review reports the recent advancement in the research of SphKs inhibitors. Our purpose is also to provide a complete overview useful for underlining the features needed to select a specific pharmacological profile.Discussion:Two distinct mammalian SphK isoforms have been identified, SphK1 and SphK2. These isoforms are encoded by different genes and exhibit distinct subcellular localizations, biochemical properties and functions. SphK1 and SphK2 inhibition can be useful in different pathological conditions.Conclusion:SphK1 and SphK2 have many common features but different and even opposite biological functions. For this reason, several research groups are interested in understanding the therapeutic usefulness of a selective or non-selective inhibitor of SphKs. Moreover, a compensatory mechanism for the two isoforms has been demonstrated, thus leading to the development of dual inhibitors.
Catheter-related Bloodstream Infections: A Root Cause Analysis in a Series of Simultaneous Ochrobactrum anthropi Infections
Authors: Caroleo Benedetto , Malandrino Pasquale , Liberto Aldo , Condorelli Dario , Patanè Federico , Maiese Aniello , Casella Filomena , Geraci Diego , Ricci Pietrantonio , Di Mizio Giulio 
Published: April 2019

Objective:Catheter-related bloodstream infections (CRBSIs) pathogenesis is complex and multifactorial mostly due to cutaneous microorganisms migration through the catheter insertion site and catheter tip colonization. Ochrobactrum anthropi is a gram-negative bacterium belonging to the Brucellaceae and related infections are especially observed in immunocompromised patients.Methods:Therefore, O. anthropi infection prevention and surveillance are relevant issues for healthcare system and risk management, in order to improve healthcare quality and patient safety. Four cases of anthropi-related CRBSIs occurring in immunodepressed patients under chemotherapy treatment are reported and the possible prevention and surveillance strategies are analyzed.Results:In the reported cases, all infections occurred almost simultaneously in the Oncology Unit, leading to hypothesize an identical infection source. Subsequently, a clinical audit was performed in order to investigate infection origin and implement prevention and control strategies. Clinical audit allowed to identify the hand hygiene defects as the primary source of the infections, responsible for catheter flushing solution contamination.Conclusion:The aim of this study is to reveal how through correct root cause analysis and clinical audit, several measures could be undertaken in order to promote the prevention of the CRBSIs risk