bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation into the Temperature Adaptability of HNIW‐based PBXs
Authors: Lan Guanchao , Jin Shaohua , Jing Baochao , Chen Yu , Wang Dongxu , Li Jinxin , Wang Na , Chen Minglei 
Published: January 2019

Abstract2,4,6,8,10,12‐Hexanitro‐2,4,6,8,10,12‐hexaazaisowurtzitane (HNIW) based polymer bonded explosives (PBXs) were prepared through an aqueous suspension method using cellulose acetate butyrate (CAB) or fluorine rubber F2311 as a binder. Then the variation rules of size, mass, surface micro‐topography, mechanical properties, thermal decomposition performance and mechanical sensitivity of the samples were investigated experimentally before and after high temperature (HT), low temperature (LT), high temperature cycle (HTC) and temperature shock (TS) tests, respectively. The results showed that the PBX columns, with the change rates of size and mass less than 1 %, were still at an acceptable level after temperature adaptability tests, and that the surface unevenness of the PBX samples followed the descending order of HT>HTC>LT>TS, which was in a good agreement with the order of mass loss. Moreover, the stability of the samples might be decreased by temperature adaptability tests, among which TS had the largest effect on both HNIW/CAB and HNIW/F2311. And a correlation between mechanical sensitivity and mechanical properties was found out through that the mechanical sensitivity of the PBXs stayed almost unchanged with a slight increase in the tensile strength of the columns after HTC whereas at least one sensitivity was increased markedly with the decline of the tensile strength after HT, LT or TS.
Dodecameric structure of a small heat shock protein from Mycobacterium marinum M
Authors: Bhandari Spraha , Biswas Sreeparna , Chaudhary Anuradha , Dutta Somnath , Suguna Kaza 
Published: January 2019

AbstractSmall heat shock proteins (sHSPs) are ATP‐independent molecular chaperones present ubiquitously in all kingdoms of life. Their low molecular weight subunits associate to form higher order structures. Under conditions of stress, sHSPs prevent aggregation of substrate proteins by undergoing rapid changes in their conformation or stoichiometry. Polydispersity and dynamic nature of these proteins have made structural investigations through crystallography a daunting task. In pathogens like Mycobacteria, sHSPs are immuno‐dominant antigens, enabling survival of the pathogen within the host and contributing to disease persistence. We characterized sHSPs from Mycobacterium marinum M and determined the crystal structure of one of these. The protein crystallized in three different conditions as dodecamers, with dimers arranged in a tetrahedral fashion to form a closed cage‐like architecture. Interestingly, we found a pentapeptide bound to the dodecamers revealing one of the modes of sHSP‐substrate interaction. Further, we have observed that ATP inhibits the chaperoning activity of the protein.
Biology and predation capacity of Parasitus bituberosus (Acari: Mesostigmata: Parasitidae) on Frankliniella occidentalis (Thysanoptera: Thripidae), and free‐living nematodes as its complementary prey
Authors: Rueda‐Ramírez Diana , Rios‐Malaver Diana , Varela‐Ramírez Amanda , Moraes Gilberto J 
Published: January 2019

AbstractBACKGROUNDParasitus bituberosus is common in rose fields and nearby vegetation around Bogotá. In rearing units, it is often aggregated, feeding on Frankliniella occidentalis edaphic phases. Preliminary observations suggested predator immatures can not reach adulthood if isolated. The objectives were to evaluate the suitability of F. occidentalis as prey for P. bituberosus, to evaluate free‐living nematodes as complementary food, and to confirm the aggregation effect on predator biology. Aggregation types: (1) isolated mites, (2) mites paired only as deutonymphs and early adulthood, and (3) mites always paired. Diets: thrips (T), nematodes (N) and thrips + nematodes (NT).RESULTSParasitus bituberosus juveniles did not feed on live F. occidentalis, but developed and oviposited on nematodes. Approximately 77% of the isolated mites died as immatures. Mortality was low (21–23%) when predators were paired at least in the deutonymph and the early adult phase. Female daily predation rates were comparable to other predators on F. occidentalis (≥2.5). Continuously paired mites had high biotic potential, especially when the diet included nematodes (rm ≥ 0.33; Ro ≥ 33.90; daily oviposition rate ≥ 10.9).CONCLUSIONThe results of this study warrant further investigation of this predator, to evaluate methods for its mass production, inclusion in conservation biocontrol programs and performance against the pest at a larger scale. © 2019 Society of Chemical Industry
Honeysuckle essential oil as a potential source of ecofriendly larvicides for mosquito control
Authors: Muturi Ephantus J , Doll Kenneth , Berhow Mark , Flor‐Weiler Lina B , Rooney Alejandro P 
Published: January 2019

AbstractBACKGROUNDSome plant essential oils have insecticidal properties against mosquitoes and can be harnessed as ecofriendly tools for mosquito control. We conducted bioassays to determine the toxicity of Italian honeysuckle (Lonicera caprifolium) essential oil and its fractions against larvae of the yellow fever mosquito, Aedes aegypti.RESULTSSixteen constituents were identified in honeysuckle essential oil compared to 15, 15, 15, and 11 constituents in fractions A, B, C, and E, respectively. The chemical constituents for fraction D were not determined due to lack of enough fraction sample. The two major constituents identified were patchouli alcohol (29.3%) and 6‐acetyl‐1,1,2,4,4,7‐hexamethyltetralin (20.6%) in whole essential oil, alpha‐bulnesene (27.6%) and 6‐acetyl‐1,1,2,4,4,7‐hexamethyltetralin (23.2%) in fraction A, unknown chemical (47.3%) and diethyl phthalate (19.5%) in fraction B, unknown chemical (38.3%) and diethyl phthalate (23.2%) in fraction C, and patchouli alcohol (58.7%) and diethyl phthalate (20.5%) in fraction E. The LC50 for whole essential oil was 34.4 ppm and significantly higher than 20.6, 19.7, 18.6, and 17.7 ppm for fractions B, C, D, and E, respectively. In contrast, fraction A was inactive. At 50 ppm, all individual constituents tested were less toxic than the whole essential oil with exception of patchouli alcohol, which caused 100% mortality.CONCLUSIONThese findings suggest that patchouli alcohol is one of the chemical constituents responsible for bioactivity of honeysuckle essential oil and some of its fractions. The findings also demonstrate that honey suckle essential oil and its fractions can be exploited as a source of ecofriendly larvicides for mosquito control. Published 2019. This article is a U.S. Government work and is in the public domain in the USA.
Efficacy and nontarget impact of zinc phosphide‐coated cabbage as a ground squirrel management tool
Authors: Baldwin Roger A , Halbritter Heather , Meinerz Ryan , Snell Laura K , Orloff Steve B 
Published: January 2019

AbstractBACKGROUNDEffective management of ground squirrels relies on an integrated pest management (IPM) approach. Rodenticides may be included in an IPM program, but they must be efficacious with minimal impact on nontarget species. A zinc phosphide‐coated green bait may meet these requirements. We established a study in northeastern California to test zinc phosphide‐coated cabbage as a management tool for Belding's ground squirrels (Urocitellus beldingi). We specifically addressed factors that would influence the efficacy of a baiting program, as well as potential exposure risk to nontarget species.RESULTSWe found that prebaiting was an important application strategy, and efficacy increased as ground squirrel abundance increased. Efficacy was also greater in western portions of the study area, likely due to greater bait consumption at western sites. Belding's ground squirrels fed most heavily on cabbage during mid‐morning and late afternoon; bait applications shortly before these time periods would increase bait consumption while minimizing nontarget risk. Bait uptake was greatest around burrow entrances. The only nontarget species observed feeding on cabbage was the California kangaroo rat (Dipodomys californicus), although they were never observed feeding on treated cabbage.CONCLUSIONZinc phosphide‐coated cabbage can be an efficacious tool for managing ground squirrels, but there will be limitations on where and how it can be used effectively. It posed a low risk to nontarget species present in our study area, but nontarget risk could vary regionally. The use of a zinc phosphide‐coated green bait should only be one part of an IPM strategy for managing ground squirrels. © 2019 Society of Chemical Industry
Hesperidin, a major flavonoid in orange juice, might not affect lipid profile and blood pressure: A systematic review and meta‐analysis of randomized controlled clinical trials
Authors: Mohammadi Mohammad , Ramezani‐Jolfaie Nahid , Lorzadeh Elnaz , Khoshbakht Yadollah , Salehi‐Abargouei Amin 
Published: January 2019

Previous studies have led to conflicting results regarding the effect of hesperidin supplementation on cardiometabolic markers. This study aimed to evaluate the efficacy of hesperidin supplementation on lipid profile and blood pressure through a systematic review and meta‐analysis of randomized controlled trials (RCTs). PubMed, Web of Science, Scopus, and Google Scholar, as well as the reference lists of the identified relevant RCTs, were searched up to May 2018. Effect sizes were pooled by using the random effects model. Ten RCTs (577 participants) were eligible to be included in the systematic review. The meta‐analysis revealed that hesperidin supplementation had no effect on serum total cholesterol (weighted mean difference [WMD] = −1.04 mg/dl; 95% confidence interval [CI]: −5.65, 3.57), low‐density lipoprotein cholesterol (WMD = −1.96 mg/dl; 95% CI [−7.56, 3.64]), high‐density lipoprotein cholesterol (WMD = 0.16 mg/dl; 95% CI [−1.94, 2.28]), and triglyceride (WMD = 0.69 mg/dl; 95% CI [−5.91, 7.30]), with no significant between‐study heterogeneity. Hesperidin supplement also had no effect on systolic (WMD = −0.85 mmHg; 95% CI [−3.07, 1.36]) and diastolic blood pressure (WMD = −0.48 mmHg; 95% CI [−2.39, 1.42]). Hesperidin supplementation might not improve lipid profile and blood pressure. Future well‐designed trials are still needed to confirm these results.
A Synthetic median control chart for monitoring the process mean with measurement errors
Authors: Tran Phuong Hanh , Tran Kim Phuc , Rakitzis Athanasios 
Published: January 2019

AbstractRecent studies show that the Shewhart median chart is widely used for detecting shifts in a process, but it is often rather inefficient in detecting small or moderate process shifts. In order to overcome this problem, a Synthetic chart can be used. This chart outperforms the Shewhart‐type chart because it uses the information about the time interval between two consecutive nonconforming samples. In this paper, we propose and study the Phase II Synthetic median control chart. A Markov chain methodology is used to evaluate the statistical performance of the proposed chart. Moreover, its performance is investigated in the presence of measurement errors, which are modelled by a linear covariate error model. We provide the results of an extensive numerical analysis with several tables and figures in order to show the statistical performance of the investigated chart, for both cases of measurement errors and no measurement errors. Finally, an example illustrates the use of the Synthetic median chart.
A new unspiked K‐Ar dating approach using laser fusion on microsamples
Authors: Wang Fei , Shi Wenbei , Guillou Hervé , Zhang Weibin , Yang Liekun , Wu Lin , Wang Yinzhi , Zhu Rixiang 
Published: January 2019

RationaleIssues induced by neutron irradiation makes40Ar/39Ar dating inapplicable in some cases. The first issue is37Ar and39Ar recoil effects during irradiation that affect fine‐grained minerals (<50 μm), such as lunar rocks, glassy groundmass, supergene minerals (e.g., illite, glauconite, Mg‐oxide, etc.). The second issue from neutron irradiation is the high radioactivity gain of iron‐rich samples such as pyrite, and the third is the production of interference nuclides during irradiation. The inherent drawbacks of conventional K‐Ar and current unspiked K‐Ar dating make it difficult to assess the reliability of age results.MethodsA new approach is proposed using well‐calibrated40Ar/39Ar standard minerals to directly quantify40Ar,38Ar and36Ar. Fish Canyon sanidine (FCs), B4M muscovite and MMhb‐1 hornblende, the widely used international standard minerals, were analyzed as unknowns to test the approach. Argon isotope analyses were carried out on a noble‐gas mass spectrometer using laser fusion on microsamples (n × 0.01 to n × 0.2 mg). A new isochron – an “inverse isochron” for K‐Ar dating – was designed.ResultsFCs and B4M yielded apparent and inverse isochron ages of 28.1 ± 0.1 and 28.0 ± 0.3 Ma, 18.2 ± 0.1 and 18.2 ± 0.5 Ma, which are consistent with the recommended ages, while the MMhb‐1 presented lower apparent and inverse isochron ages (510.8 ± 4.8 and 512.3 ± 17.0 Ma) than the recommended ones. The initial argon compositions for the three standard minerals are 299.2 ± 205.3 (FCs), 294.0 ± 16.4 (B4M) and 290.9 ± 203.1 (MMhb‐1), agreeing with that of air.ConclusionsThe proposed approach potentially overcomes the issues of40Ar/39Ar rising from irradiation and the drawbacks of K‐Ar. By using laser fusion on multiple microaliquots from a same sample, this approach can produce accurate and precise K‐Ar ages and give an inverse isochron. This new approach may provide an alternate dating method of geochronology based on argon isotopes.
Stereoselective Approach towards the Synthesis of 3R, 5 S Gingerdiol and 3 S, 5 S Gingerdiol
Authors: Markad Sachin B. , Bhosale Viraj A. , Bokale Suvarna R. , Waghmode Suresh B. 
Published: January 2019

AbstractAn operationally simple and concise stereoselective synthesis of both natural 3R, 5 S gingerdiol and 3 S, 5 S gingerdiol has been achieved from achiral n‐heptanal by employing iterative proline catalysed α‐aminoxylation, followed by Horner−Wadsworth−Emmons or Wittig olefination reactions as key steps. The adducts formed in high enantiopurity as well as syn or anti‐1,3‐diols units were synthesized with excellent diastereoselectivity from γ‐hydroxy aldehyde by using D or L‐ proline.
Synthesis of Si‐Doped CNT and Its Catalytic Ability in Hydrogen Evolution Reaction
Authors: Bakhshi Pourya , Tavakol Hossein 
Published: January 2019

AbstracthSilicon doped carbon nanotubes (SiCNTs) have been synthesized using Fe/CaCO3 as catalyst and acetylene and silane as precursors using chemical vapor deposition (CVD). The growth temperature was considered as a variable and its effect on the structure of the product was investigated. All conditions were optimized and the optimum temperature was 650 °C. The insertion of silicon atom in the structure of carbon nanotubes showed some changes in the properties and structure of this product, which have been investigated using FESEM, TEM, XRD, Raman, EDS, DTA and TGA. The produced SiCNTs showed high thermal stabilities, based on the results of TGA and DTA analyses. The electrocatalytic properties of SiCNTs were examined in hydrogen evolution reaction (HER) and according to the obtained LSV and Tafel diagrams (based on comparing them with the previous reports for non‐metal electrocatalyst), the prepared SiCNTs have shown acceptable values (the second rank for each case) for onset potential, Tafel slope and η, which confirmed its appropriate electrocatalytic ability for HER.
Ultrathin Dual‐Scale Nano‐ and Microporous Membranes for Vascular Transmigration Models
Authors: Salminen Alec T. , Zhang Jingkai , Madejski Gregory R. , Khire Tejas S. , Waugh Richard E. , McGrath James L. , Gaborski Thomas R. 
Published: January 2019

AbstractSelective cellular transmigration across the microvascular endothelium regulates innate and adaptive immune responses, stem cell localization, and cancer cell metastasis. Integration of traditional microporous membranes into microfluidic vascular models permits the rapid assay of transmigration events but suffers from poor reproduction of the cell permeable basement membrane. Current microporous membranes in these systems have large nonporous regions between micropores that inhibit cell communication and nutrient exchange on the basolateral surface reducing their physiological relevance. Here, the use of 100 nm thick continuously nanoporous silicon nitride membranes as a base substrate for lithographic fabrication of 3 µm pores is presented, resulting in a highly porous (≈30%), dual‐scale nano‐ and microporous membrane for use in an improved vascular transmigration model. Ultrathin membranes are patterned using a precision laser writer for cost‐effective, rapid micropore design iterations. The optically transparent dual‐scale membranes enable complete observation of leukocyte egress across a variety of pore densities. A maximal density of ≈14 micropores per cell is discovered beyond which cell–substrate interactions are compromised giving rise to endothelial cell losses under flow. Addition of a subluminal extracellular matrix rescues cell adhesion, allowing for the creation of shear‐primed endothelial barrier models on nearly 30% continuously porous substrates.
CRISPR/Cas9‐Based Genome Editing and its Applications for Functional Genomic Analyses in Plants
Authors: Li Jun , Li Yan , Ma Ligeng 
Published: January 2019

AbstractThe ability to modify complex genomes precisely to create specific mutants is the holy grail of basic research and applied genetics in the postgenomic era. Programmable sequence‐specific nucleases (e.g., zinc finger nucleases, transcription activator‐like effector nucleases, and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated (Cas) systems (e.g., CRISPR/Cas9)), which induce targeted DNA breaks that are then repaired by endogenous repair machinery to generate mutants in a variety of organisms, are being developed at an unprecedented rate. Herein, this paper reviews the history, structure, and biological function of CRISPR/Cas systems, describing how it has been adapted for genome editing (especially CRISPR/Cas9, which has prompted a genome engineering revolution), and emphasizes recent applications and advances in the functional annotation of plant genomes and crop genetic improvement. In addition, the challenges of using the CRISPR/Cas9 system and strategies for improving its specificity are discussed. This review also introduces the creation of CRISPR‐edited DNA‐free plants, which may be more publicly acceptable than other genetically modified organisms. Finally, the future directions and applications of the CRISPR/Cas9 system are speculated on.
K competing queues with customer abandonment: optimality of a generalised $$c \mu $$-rule by the Smoothed Rate Truncation method
Authors: Bhulai S. , Blok H. , Spieksma F. M. 
Published: January 2019

AbstractWe consider a K-competing queues system with the additional feature of customer abandonment. Without abandonment, it is optimal to allocate the server to a queue according to the $$c \mu $$

c
μ

-rule. To derive a similar rule for the system with abandonment, we model the system as a continuous-time Markov decision process. Due to impatience, the Markov decision process has unbounded jump rates as a function of the state. Hence it is not uniformisable, and so far there has been no systematic direct way to analyse this. The Smoothed Rate Truncation principle is a technique designed to make an unbounded rate process uniformisable, while preserving the properties of interest. Together with theory securing continuity in the limit, this provides a framework to analyse unbounded rate Markov decision processes. With this approach, we have been able to find close-fitting conditions guaranteeing optimality of a strict priority rule.
Mating Performance: Exploring Emotional Intelligence, the Dark Triad, Jealousy and Attachment Effects
Authors: Apostolou Menelaos , Paphiti Christiana , Neza Eleni , Damianou Maria , Georgiadou Polyxeni 
Published: January 2019

AbstractA considerable proportion of the population in post-industrial societies experiences substantial difficulties in the domain of mating. The current research attempted to estimate the prevalence rate of poor mating performance and to identify some of its predictors. Two independent studies, which employed a total of 1,358 Greek-speaking men and women, found that about 40% of the participants experienced poor performance in either starting or keeping an intimate relationship, or in both areas. Furthermore, emotional intelligence, Dark Triad traits, jealousy, and attachment style were found to be significant predictors of mating performance. In particular, higher emotional intelligence and narcissism were associated with higher performance in mating, while higher psychopathy, jealousy and an avoidant attachment style were associated with lower mating performance.
Did family size affect differences in body height in non-urbanized societies? Evidence from the Lemko community in Poland in the late 19th and early 20th centuries
Authors: Czapla Zbigniew , Liczbińska Grażyna , Nowak Oskar , Piontek Janusz 
Published: January 2019

AbstractThe aim of this study was to examine the effect of economic changes in the Polish territories under Austrian partition at the end of the 19th and the beginning of the 20th centuries on the trend in adult body height, and to examine the effect of number of children in a family, as a socioeconomic factor, on the differences in heights of males and females. Data collected in a 1939 survey for a group of 350 Lemkos living in Polish lands under the Austrian partition were obtained from archive material. Individual data were obtained for body height and number of siblings, to calculate family size. Linear regression analysis confirmed an increase in body height in males by about 1.2 cm per decade over the period 1860 to 1922. The number of children in a family did not appear to influence the mean body height of men and women. The observed positive mean body height trend probably resulted from the improvement in the economic conditions in the Austrian sector over the survey period.
Re-Orienting the Philippines: The KALIBAPI party and the application of Japanese Pan-Asianism, 1942–45
Authors: MATTHIESSEN SVEN 
Published: January 2019

AbstractDuring their occupation of the Philippines from 1942 to 1945, the Japanese invaders aimed at making the archipelago become part of the so-called Greater East Asia Co- Prosperity Sphere (GEACPS,Daitōa kyōeiken)—a self-sustaining economic bloc that should act as a bulwark against Western imperialism. The underlying philosophy of the GEACPS was pan-Asianism (Han Ajia-shugi)—an ideology that propagated the liberation and unity of all Asian peoples. In the Philippines, the Japanese administrators faced various problems with the implementation of this ideology. The strong impact of four centuries under Western colonial rule had created a mindset among many Filipinos that they themselves were Westerners and not Asians. Therefore, one of the main purposes of the new Japanese rulers was to change the attitude of the Philippine population and win the Filipinos over to the concept of the GEACPS. One means to this end was the dissolution of all political parties in the Philippines and replacing them with theKapisanan sa Paglilingkod sa Bagong Pilipinas(KALIBAPI: lit., ‘Association for Service to the New Philippines’). The Japanese wanted to turn this association into a mass organization with the ultimate goal to create a mass movement towards the establishment of the ‘New Philippines’ among the population. In this article, I will discuss how the Japanese administrators used the KALIBAPI to adopt their pan-Asianism to Philippine circumstances, but also how the organization exemplifies the ultimate failure of Japanese pan-Asianism in the Philippines.