bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percutaneous puncture and embolisation for pancreatitis-related pseudoaneurysm: the feasibility of thrombin injection even in collection of fluid surrounding the pseudoaneurysm
Authors: Michimoto Kenkichi , Higuchi Takahiro , Enoki Keitaro , Matsui Yo , Takenaga Shinsuke , Saeki Chisato 
Published: January 2019

PurposePancreatitis-related pseudoaneurysm, a potentially life-threatening condition, is treated utilising endovascular management as a first choice and alternatively by percutaneous direct puncture of the aneurysm and embolisation.Case reportA 50-year-old man with alcohol-induced necrotic pancreatitis underwent transcatheter arterial embolisation (TAE) for multiple pancreatic pseudoaneurysms. TAE failed in one enlarged aneurysm in the pancreatic body, and percutaneous direct needle puncture and coagulation using thrombin was planned. Precise puncture of the aneurysmal sac under fluoroscopy and computed tomographic (CT) guidance failed, but we could inject about 500 units of thrombin through the outer cannula into the collection of fluid surrounding the aneurysm. Compared to preoperative images, contrast-enhanced CT (CECT) showed shrinkage of the pseudoaneurysm without complications just after the procedure and its disappearance five days after the procedure.ConclusionsPercutaneous direct puncture and embolisation is a feasible choice to treat pancreatic pseudoaneurysms, and injection of thrombin even into the collection of fluid surrounding the pseudoaneurysm can be a viable alternative, especially in cases in which precise puncture of the aneurysmal sac is difficult because of its size and location.
Global tropospheric effects of aromatic chemistry with the SAPRC-11 mechanism implemented in GEOS-Chem version 9-02
Authors: Yan Yingying , Cabrera-Perez David , Lin Jintai , Pozzer Andrea , Hu Lu , Millet Dylan B. , Porter William C. , Lelieveld Jos 
Published: January 2019

Abstract. The Goddard Earth Observing System with chemistry (GEOS-Chem) model has been
updated with the State-wide Air Pollution Research Center version 11 (SAPRC-11) aromatics chemical
mechanism, with the purpose of evaluating global and regional effects of the
most abundant aromatics (benzene, toluene, xylenes) on the chemical species
important for tropospheric oxidation capacity. The model evaluation based on
surface and aircraft observations indicates good agreement for aromatics and
ozone. A comparison between scenarios in GEOS-Chem with simplified aromatic
chemistry (as in the standard setup, with no ozone formation from related
peroxy radicals or recycling of NOx) and with the SAPRC-11 scheme
reveals relatively slight changes in ozone, the hydroxyl radical, and nitrogen
oxides on a global mean basis (1 %–4 %), although remarkable regional
differences (5 %–20 %) exist near the source regions. NOx decreases
over the source regions and increases in the remote troposphere, due mainly
to more efficient transport of peroxyacetyl nitrate (PAN), which is
increased with the SAPRC aromatic chemistry. Model ozone mixing ratios with
the updated aromatic chemistry increase by up to 5 ppb (more than 10 %),
especially in industrially polluted regions. The ozone change is partly due
to the direct influence of aromatic oxidation products on ozone production
rates, and in part to the altered spatial distribution of NOx that
enhances the tropospheric ozone production efficiency. Improved
representation of aromatics is important to simulate the tropospheric oxidation.
O escola sem partido e o discurso sobre uma suposta "ideologia de gênero"
Authors: Aparecida de Carvalho Fabiana , Luiz Polizel Alexandre 
Published: January 2019

Numa análise discursiva amparada por teorizações foucaultianas e feministas, o presente artigo aponta as distorções ideológicas do Escola Sem Partido (ESP), os efeitos constitutivos dos Projetos de Lei em tramitação e os efeitos de dispositivo que tensionam docilizar os corpos, apagar a alteridade e a diversidade escolar e gerar a contraposição à construção cultural do gênero. O ESP é uma proposição de cunho neoliberal que se coliga com interesses conservadores e performa uma biopolítica escolar. O cruzamento com o combate à uma suposta "ideologia de gênero", a recusa do feminismo e da militância e a coligação com outros movimentos conservadores estão destacados, ao longo da escrita, como dispositivos que ameaçam a liberdade de expressão, as práticas docentes e a pluralidade de ideias nas escolas brasileiras.
A persistência do trote universitário e da violência no contexto educacional
Authors: Eduardo Ramos Carlos , Lucas Rodrigues de Sousa Caobe 
Published: January 2019

O objetivo deste artigo é compreender, a partir da perspectiva da Teoria Crítica da Sociedade, como ocorrem os trotes universitários na Universidade Federal de Roraima (UFRR). Para a coleta de dados foram realizadas observações assistemáticas em trotes dos cursos de medicina e engenharia, e entrevistas com alunos pertencentes a diversos cursos da instituição que já participaram do trote. Foi possível constatar que o trote busca, em certa medida, se adequar ao modelo tradicional (marcado pelas situações vexatórias, violência psicológica, etc.) e os motivos pelos quais essa prática é defendida estão principalmente vinculados à adesão do indivíduo ao grupo. Os resultados da pesquisa permitiram a produção de um enredamento entre questões que, superficialmente, parecem não possuir conexões imediatas, mas que não podem ser ignoradas para se compreender a cultura do trote no contexto da universidade.
‘Here is the voice of the people’: Authority and Conflict in Eighteenth-Century Methodism
Authors: Norris Clive Murray 
Published: January 2019

ABSTRACT
This article discusses issues of authority and conflict in John Wesley's Connexion in the eighteenth century, drawing on the example of the itinerant preacher Thomas Wride (1733–1807), who was embroiled in constant controversy. It explains that the tensions between Wride and his congregations and colleagues arose not simply from his alleged eccentricity, but reflected deep-seated differences about worship and discipline. A thoughtful and energetic pastor, and a dutiful administrator, Wride's punctiliousness and insensitivity in enforcing adherence to the movement's rules as he saw them undermined his effectiveness. His career, as recorded in his own often colourful words, exposes struggles within early Wesleyan Methodism that are not always evident in the movement's extensive official history.
Curved Hull Plate Classification for Determining Forming Method using Deep Learning
Authors: Kim Byeongseop , Son Seunghyeok , Ryu Cheolho , Shin Jong Gye 
Published: January 2019

Curved hull plate forming, the process of forming a flat plate into a curved surface that can fit into the outer shell of a ship's hull, can be achieved through either cold or thermal forming processes, with the latter processes further subcategorizable into line or triangle heating. The appropriate forming process is determined from the plate shape and surface classification, which must be determined in advance to establish a precise production plan. In this study, an algorithm to extract two-dimensional features of constant size from three-dimensional design information was developed to enable the application of machine and deep learning technologies to hull plates with arbitrary polygonal shapes. Several candidate classifiers were implemented by applying learning algorithms to datasets comprising calculated features and labels corresponding to various hull plate types, with the performance of each classifier evaluated using cross-validation. A classifier applying a convolution neural network as a deep learning technology was found to have the highest prediction accuracy, which exceeded the accuracies obtained in previous hull plate classification studies. The results of this study demonstrate that it is possible to automatically classify hull plates with high accuracy using deep learning technologies and that a perfect level of classification accuracy can be approached by obtaining further plate data.

1. Introduction
The outer shell of a ship is composed of hull plates that are generally formed as curved surfaces. To produce a curved surface from a flat steel plate, a curved hull plate-forming process involving the application of heat or pressure to the plate must be undertaken. Such forming processes can be categorized as either cold forming, in which the plate is bent using physical pressure, or thermal forming, in which bending stress is generated by applying heat to the plate. The former process is generally used to bend plates into cylindrical shapes using a rolling machine, whereas the latter is used to form more complex curved surfaces. In most shipyards, thermal forming is performed by skilled workers who apply direct heat to plates using a torch; accordingly, thermal forming is more difficult and time-consuming than machine-based cold forming and often constitutes a crucial bottleneck process in shipyard operation.
Correlation of antidepressant target dose optimization and achievement of glycemic control
Authors: Grisham-Takac Catlin , Lai Phillip , Srinivasa Maaya , Vasquez Lindsay , Rascati Karen L. 
Published: January 2019

Abstract

Introduction
Depression is a recognized cause of disability globally with a propensity to be comorbid in patients with diabetes, leading to poorer health-related outcomes. Although a number of studies have investigated the correlation between improvement in depression and chronic disease, none have reported on achievement of target doses of antidepressant therapies and diabetes control. The objective of this study is to determine the influence of antidepressant dosing optimization on reducing hemoglobin A1c (HbA1c).

Methods
This was a retrospective cohort study of patients seen at CommUnityCare Health Centers who were initiated on an antidepressant and had uncontrolled diabetes (HbA1c &gt; 7%). Eligible patients were followed for 12 months after initiation and separated into those who achieved target dose and those who did not. Patient health questionnaire scores were collected when available in an attempt to quantify change in depressive symptoms.

Results
A total of 178 patients met inclusion criteria with 76 achieving an optimal dose (target group) and 102 patients below optimal dose (control group) at the end of the study period. Patients in both groups were similar at baseline with an HbA1c of 9.29% compared to 9.24% in the target and control groups, respectively. At the end of the study period, more patients in the target group achieved an HbA1c &lt; 7% (22.9%, n = 48 vs 4.3%, n = 23, respectively; P &lt; .05).

Discussion
These results suggest that optimization of antidepressant dosing in patients with diabetes may lead to an increased likelihood of reaching goal HbA1c &lt; 7% although correlation to improvement of depression remains unknown.
Pharmacists' attitudes, interest, and perceived skills regarding suicide prevention
Authors: Cates Marshall E. , Hodges Jordan R. Cochran , Woolley Thomas W. 
Published: January 2019

Abstract

Introduction
Pharmacists have been called upon to be involved in suicide prevention efforts, but little is known regarding their attitudes, interest, and perceived skills in the area.

Methods
The study was a voluntary, anonymous survey of pharmacists who attended a large end-of-year continuing education program sponsored by a school of pharmacy. The survey included the Attitudes to Suicide Prevention (ASP) Scale, items concerning interest in suicide prevention, and items from the suicide skills section of the Suicide Knowledge and Skills Questionnaire.

Results
The survey was completed by 227/297 (76.4%) pharmacists. The percentage of participants who expressed interest in direct involvement, indirect involvement, and receiving training in suicide prevention were 25%, 46%, and 56%, respectively. The mean total score on the ASP was 32.2 ± 5.5. Approximately 4% to 8% of participants agreed that they had the requisite training, skills, or support/supervision to engage and assist suicidal patients, and 22% agreed to feeling comfortable asking their patients direct and open questions about suicide. The ASP scores and items relating to perceived skills were correlated with interest in direct involvement in suicide prevention.

Discussion
There were some positive findings, but overall, the pharmacists who participated in this survey felt unprepared to be frontline clinicians in suicide prevention efforts. Further studies should be conducted to determine if these findings are generally reflective of the broader pharmacy community. If the profession is to have a serious role in suicide prevention, then adequate suicide prevention training for pharmacy students and pharmacists may be necessary.
Annotations of the nursing team: the (dis) appreciation of care for the information provided / Anotações da equipe de enfermagem: a (des)valorização do cuidado pelas informações fornecidas
Authors: Caldeira Mariana Menezes , Souza Tania Vignuda , Morais Rita de Cássia Melão , Moraes Juliana Rezende Montenegro Medeiros , Nascimento Luciana de Cássia Nunes , Oliveira Isabel Cristina Santos 
Published: January 2019

Objetivos: analisar as anotações da equipe de enfermagem nos prontuários de crianças hospitalizadas e discutir as informações descritas pela enfermagem e suas implicações para a assistência à criança. Métodos: Pesquisa qualitativa desenvolvida em enfermaria pediátrica de Hospital Geral. Dados extraídos da consulta em prontuários. Análise temática. Resultados: As anotações estavam relacionadas a dados que indicavam funcionamento gastrintestinal, atividade motora, interpretação das alterações dos sinais vitais, uso de dispositivos tecnológicos, e cuidados de enfermagem como curativos e higiene corporal. O espaço destinado à anotação da equipe de enfermagem era restrito a folha de prescrição médica que era ínfimo e não havia identificação do profissional. Conclusão: Os profissionais de enfermagem se limitavam a descrever na folha de prescrição médica informações que não refletiam o seu cuidado e a real condição clínica da criança quanto à qualidade da assistência de enfermagem. Em contrapartida, não havia um movimento dos próprios profissionais de enfermagem para garantir um espaço no prontuário como membro da equipe de saúde.
Infections in temporary access for hemodialysis in chronic renal failure patients / Infecção em acesso temporário para hemodiálise em pacientes com insuficiência renal crônica
Authors: Reisdorfer Arion Saraiva , Giugliani Roberto , Gouveia Viviane de Araújo , Dos Santos Emmanuela Kethully Mota , Da Silva José Jairo Teixeira 
Published: January 2019

Objetivo: Avaliar a ocorrência de infecções em pacientes com insuficiência renal crônica em uso do cateter temporário duplo-lúmen (CTDL). Métodos: Estudo prospectivo ou de seguimento, realizado em uma Clínica de Nefrologia, em Recife (PE), Brasil, entre os meses de janeiro de 2009 a dezembro de 2010. A coleta foi realizada através da avaliação clínica e de prontuários de 88 pacientes com insuficiência renal crônica (IRC), em tratamento hemodialítico. Os dados foram analisados através da quantificação das variáveis contidas no instrumento de coleta. Resultados: A infecção do sítio de inserção do cateter ocorreu em 52,3%, dos pacientes e em 47,7%, foi verificado a infecção da corrente sanguínea associada ao cateter. Conclusão: É primordial a conscientização da equipe de saúde em relação aos cuidados na implantação e manipulação do catéter. As condições de higiene do paciente contribuem com processos infecciosos, sendo assim, precisam ser informados sobre os riscos de infecção.
Domain shuffling of cyclodextrin glucanotransferases for tailored product specificity and thermal stability
Authors: Sonnendecker Christian , Zimmermann Wolfgang 
Published: January 2019

Cyclodextrin glucanotransferases (CGTases) convert α‐1,4‐glucans to cyclic oligosaccharides (cyclodextrins, CD), which have found applications in the food and the pharmaceutical industries. In this study, we used two CGTases with different cyclization activities, product specificities, and pH and temperature optima to construct chimeric variants for the synthesis of large‐ring CD. We used (a) a synthetic thermostable CGTase mainly forming α‐ and β‐CD (CD6 and CD7) derived from Geobacillus stearothermophilus ET1/NO2 (GeoT), and (b) a CGTase with lower cyclization activity from the alkaliphilic Bacillus sp. G825‐6, which mainly synthesizes γ‐CD (CD8). The A1, B, A2, and CDE domains of the G825‐6 CGTase were replaced with corresponding GeoT CGTase domains by utilizing a megaprimer cloning approach. A comparison of the optimum temperature and pH, thermal stability, and CD products synthesized by the variants revealed that the B domain had a major impact on the cyclization activity, thermal stability, and product specificity of the constructed chimera. Complete suppression of the synthesis of CD6 was observed with the variants GeoT‐A1/B and GeoT‐A1/A2/CDE. The variant GeoT‐A1/A2/CDE showed the desired enzyme properties for large‐ring CD synthesis. Its melting temperature was 9 °C higher compared to the G825‐6 CGTase and it synthesized up to 3.3 g·L−1 CD9 to CD12, corresponding to a 1.8‐ and 2.3‐fold increase compared to GeoT and G825‐6 CGTase, respectively. In conclusion, GeoT‐A1/A2/CDE may be a candidate for the further development of CGTases specifically forming larger CD.
Flexible Multifunctional Sensors for Wearable and Robotic Applications
Authors: Xie Mengying , Hisano Kyohei , Zhu Mingzhu , Toyoshi Takuya , Pan Min , Okada Shima , Tsutsumi Osamu , Kawamura Sadao , Bowen Chris 
Published: January 2019

AbstractThis review provides an overview of the current state‐of‐the‐art of the emerging field of flexible multifunctional sensors for wearable and robotic applications. In these application sectors, there is a demand for high sensitivity, accuracy, reproducibility, mechanical flexibility, and low cost. The ability to empower robots and future electronic skin (e‐skin) with high resolution, high sensitivity, and rapid response sensing capabilities is of interest to a broad range of applications including wearable healthcare devices, biomedical prosthesis, and human–machine interacting robots such as service robots for the elderly and electronic skin to provide a range of diagnostic and monitoring capabilities. A range of sensory mechanisms is examined including piezoelectric, pyroelectric, piezoresistive, and there is particular emphasis on hybrid sensors that provide multifunctional sensing capability. As an alternative to the physical sensors described above, optical sensors have the potential to be used as a robot or e‐skin; this includes sensory color changes using photonic crystals, liquid crystals, and mechanochromic effects. Potential future areas of research are discussed and the challenge for these exciting materials is to enhance their integration into wearables and robotic applications.
A Data‐Driven Accelerated Sampling Method for Searching Functional States of Proteins
Authors: Zhu Qiang , Yuan Yigao , Ma Jing , Dong Hao 
Published: January 2019

AbstractProtein exhibits distinct characteristics in different functional states. The lack of structural information for proteins hinders the understanding of their function. Here, a data‐driven accelerated (DA2) sampling method is proposed, which is capable of searching new functional states of protein from a known structure with high efficiency. The key function of DA2 sampling is to drive the conformational change of protein along its intrinsic motion without introducing biased potential/force, where principle component analysis is applied on‐the‐fly to reduce the highly redundant information generated by molecular dynamics simulations. In this work, the capacity and accuracy of DA2 sampling are validated by using alanine dipeptide. This protocol is then applied to search for the closed state of N‐terminal calmodulin (nCaM) from the open one. The identified structure resembles the crystal structure of nCaM in its closed state, with a root‐mean‐square deviation between the two of only 1.8 Å. Interestingly, independent DA2 samplings disclose different open‐to‐closed transition pathways for nCaM, which is likely to have implications for its biological functions. Therefore, DA2 sampling is expected to play important roles in exploring functional states of a broad spectrum of proteins at atomic level that are not easily determined experimentally.
Waterproof Fabric‐Based Multifunctional Triboelectric Nanogenerator for Universally Harvesting Energy from Raindrops, Wind, and Human Motions and as Self‐Powered Sensors
Authors: Lai Ying‐Chih , Hsiao Yung‐Chi , Wu Hsing‐Mei , Wang Zhong Lin 
Published: January 2019

AbstractDeveloping nimble, shape‐adaptable, conformable, and widely implementable energy harvesters with the capability to scavenge multiple renewable and ambient energy sources is highly demanded for distributed, remote, and wearable energy uses to meet the needs of internet of things. Here, the first single waterproof and fabric‐based multifunctional triboelectric nanogenerator (WPF‐MTENG) is presented, which can produce electricity from both natural tiny impacts (rain and wind) and body movements, and can not only serve as a flexible, adaptive, wearable, and universal energy collector but also act as a self‐powered, active, fabric‐based sensor. The working principle comes from a conjunction of contact triboelectrification and electrostatic induction during contact/separation of internal soft fabrics. The structural/material designs of the WPF‐MTENG are systematically studied to optimize its performance, and its outputs under different conditions of rain, wind, and various body movements are comprehensively investigated. Its applicability is practically demonstrated in various objects and working situations to gather ambient energy. Lastly, a WPF‐MTENG‐based keypad as self‐powered human–system interfaces is demonstrated on a garment for remotely controlling a music‐player system. This multifunctional WPF‐MTENG, which is as flexible as clothes, not only presents a promising step toward democratic collections of alternative energy but also provides a new vision for wearable technologies.
Realizing Three‐Electron Redox Reactions in NASICON‐Structured Na3MnTi(PO4)3 for Sodium‐Ion Batteries
Authors: Zhu Ting , Hu Ping , Wang Xuanpeng , Liu Zhenhui , Luo Wen , Owusu Kwadwo Asare , Cao Weiwei , Shi Changwei , Li Jiantao , Zhou Liang , Mai Liqiang 
Published: January 2019

AbstractDeveloping multielectron reaction electrode materials is essential for achieving high specific capacity and high energy density in secondary batteries; however, it remains a great challenge. Herein, Na3MnTi(PO4)3/C hollow microspheres with an open and stable NASICON framework are synthesized by a spray‐drying‐assisted process. When applied as a cathode material for sodium‐ion batteries, the resultant Na3MnTi(PO4)3/C microspheres demonstrate fully reversible three‐electron redox reactions, corresponding to the Ti3+/4+ (≈2.1 V), Mn2+/3+ (≈3.5 V), and Mn3+/4+ (≈4.0 V vs Na+/Na) redox couples. In situ X‐ray diffraction results reveals that both solid‐solution and two‐phase electrochemical reactions are involved in the sodiation/desodiation processes. The high specific capacity (160 mAh g−1 at 0.2 C), outstanding cyclability (≈92% capacity retention after 500 cycles at 2 C), and the facile synthesis make the Na3MnTi(PO4)3/C a prospective cathode material for sodium‐ion batteries.