bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aerosol versus Greenhouse Gas Effects on Tropical Cyclone Potential Intensity and the Hydrologic Cycle
Authors: Sobel Adam H. , Camargo Suzana J. , Previdi Michael 
Published: June 2019

AbstractAerosol cooling reduces tropical cyclone (TC) potential intensity (PI) more strongly, by about a factor of 2 per degree of sea surface temperature change, than greenhouse gas warming increases it. This study analyzes single-forcing and historical experiments from phase 5 of the Coupled Model Intercomparison Project, aiming to understand the physical mechanisms behind this difference. Calculations are done for the tropical oceans of each hemisphere during the relevant TC seasons, emphasizing multimodel means. PI theory is used to interpret the difference in the PI response to aerosol and greenhouse gas forcings in terms of three factors. The net surface turbulent heat flux (sum of the latent and sensible heat fluxes) explains half of the difference, thermodynamic efficiency explains at most a small fraction, and surface wind speed does not explain the remainder, perhaps because of the use of monthly mean data. Changes in turbulent surface heat fluxes are interpreted as responses to surface radiative flux changes in the context of the energy balance of the ocean mixed layer. Radiative kernels are used to estimate what fractions of the surface radiative flux changes are feedbacks due to temperature and water vapor changes. The greater effect of aerosol forcing occurs because shortwave forcing has a greater direct, temperature-independent component at the surface than does longwave forcing, for a forcing amplitude that provokes the same SST change. This conclusion recalls prior work on the response of precipitation to radiative forcing, and the similarities and differences between precipitation and potential intensity in this regard are discussed.
Evaluating Alternative Drought Indicators in a Weather Index Insurance Instrument
Authors: Williams Travis M. , Travis William R. 
Published: June 2019

Abstract
Weather index insurance is a popular means of mitigating agricultural risks. Drought is a significant cause of lost agricultural production, and so precipitation index–based plans are common. Simple “percent of normal” indices are often used because they are easy to calculate and communicate to policyholders. However, the ability of such indices to reflect production losses is limited, reducing the ability of insurance to efficiently mitigate risk. This is especially true in rangeland livestock production given the cumulative effects of rainfall and other factors on range production and the complex relationships between range and livestock weight gain, which is the rancher’s main product and source of income. More sophisticated drought indices incorporate the complexities of drought into their design and would, in theory, serve as more appropriate payment triggers. This study uses a suite of drought indices to test correlation with production and the behavior of insurance based on those indices. Payout patterns based on each index were simulated within the actuarial framework of a precipitation-based insurance program aimed at livestock producers. Results were compared with the program’s precipitation index, showing that drought indices have higher correlations with range production, a tendency to incentivize growing-season protection, more even geographic distributions of risk, reduced policyholder ability to seek higher payments through strategic coverage choices, and increased provider ability to adjust payment patterns to reduce the risk of nonpayment given loss.
Head and Neck Cancer Complications in the Geriatric Population Based on Hospital Case Volume
Authors: Rubin Samuel J. , Wu Kevin Y. , Kirke Diana N. , Ezzat Waleed H. , Truong Minh Tam , Salama Andrew R. , Jalisi Scharukh 
Published: June 2019

Objective: To determine whether surgical case volume is a predictive factor of surgical outcomes when managing geriatric patients with head andneck cancer. Methods: A cross-sectional study design was used. Data were obtainedfrom the Vizient Database, which included a total of 93 academicinstitutions. Men and women aged between 65 and 100 years undergoing head and neck cancer surgery during 2009 and 2012,excluding cases of thyroid cancer and skin cancer of the head and neck(n = 4544) were included in the study. Hospital case volume was definedas low (≤21 cases/year), moderate (22-49 cases/year), or high (≥50 cases/year). The frequency of comorbidities and complications wasmeasured by hospital case volume using a χ2 test. Significancewas determined with an α level of .05. Results: The largest number of head and neck cancer cases involving comorbidities (90.54%) and the highest rate of overall complications(27.50%) occurred in moderate case volume institutions compared to athe complication rate of 22.89% in low volume hospitals and 21.50% in highvolume hospitals ( P < .0001). The most common comorbidities across all3 hospital case volumes included hypertension, metastatic cancer,and chronic pulmonary disease and the most common complicationsincluded hemorrhage/hematoma and postoperative pulmonarycompromise. Conclusion: With more geriatric patients requiring surgery for head andneck cancer, it would be beneficial to manage the more complex cases at high volume centers and to develop multidisciplinary teams to optimizecase management and minimize complications.
Empowering students to take ownership of their learning: Lessons from one piano teacher’s experiences with transformative pedagogy
Authors: Coutts Leah 
Published: June 2019

As the number of adults seeking to learn the piano increases, so too does the need for piano teachers to understand how to better facilitate their learning. Self-direction is an oft-cited requirement of adult learning, but one that is often absent from piano studios. This practitioner-based research investigates the role of the teacher in fostering and supporting self-direction, empowering adult piano students to take ownership of their learning. It offers pedagogical insights into the author’s experiences within her own piano studio and details the practical application of theories and strategies offered within the fields of piano pedagogy and adult learning. This study finds that fostering self-direction is more complex than offering the balance between guidance and freedom that some experts suggest. It also requires strong student–teacher rapport, supporting and building students’ self-efficacy and being willing to set aside expectations. This was made possible by implementing transformative pedagogical strategies, such as effective questioning, collaborative discussions and adapting the structure of lessons. While the author’s journey is uniquely her own, the approaches used to engage adult students with their learning, and the use of reflective practice as professional development, may be of interest to other studio instrumental teachers.
The Joint Dynamics of Liquidity and Volatility Across Small- and Large- index Indian Funds
Authors: Kulshrestha Kriti , Bhaduri Saumitra N. 
Published: June 2019

The article explores the relationship between volatility and liquidity, as there is a change in market capitalisation (cap). Using three regimes of volatility, identified by the threshold vector auto-regression method, the results show that volatility affects liquidity differently for the three volatility regimes during the two periods (crisis and post-crisis) of study. The results show that there is inconsistency in how volatility affects liquidity across the Indian large-, mid- and small-cap indices. JEL Classification: G1 G17
An Oral Health-Related Quality of Life Comparison Between Adults With Unilateral Cleft Lip and Palate and Class III Malocclusion
Authors: Barros Leandro Almeida Nascimento , Jesuino Flávia Aline Silva , de Paiva João Batista , Rino-Neto José , Valladares-Neto José 
Published: June 2019

Objective: To compare oral health-related quality of life (OHRQoL) before treatment of adults with unilateral cleft lip and palate (UCLP) and surgical Class III malocclusion, and to consider if clefts needing different orthodontic treatment protocols could influence people’s self-perception. Design: Cross sectional. Setting: Cleft Lip and Palate Center and Clinic of Orthognathic Surgery from a School of Dentistry. Participants: A sample of adults with repaired nonsyndromic UCLP (n = 52) which was age- and sex-matched with a noncleft Class III malocclusion sample seeking orthognathic surgery (n = 51). In turn, the cleft group was subdivided according to treatment planning into nonsurgical orthodontic and surgical orthodontic approaches. Main Outcome Measure: The whole sample was assessed using the short-form oral health impact profile (OHIP-14), with higher scores indicating a poorer OHRQoL. Statistical comparisons were performed with Mann-Whitney U and Kruskal-Wallis tests, and effect size. Bonferroni adjustment was used for post hoc tests ( P < .017). Results: The OHIP-14 scores of the UCLP and Class III groups were significantly different ( P = .001, η2 = 0.108), and higher in Class III. The largest commitment was in the physical disability, physical pain, and psychological disability domains. In addition, no differences were found when the UCLP treatment planning was considered. Conclusion: Surgical Class III malocclusion have a poorer OHRQoL when compared to patients with UCLP, irrespective of whether they are treated surgically or orthodontically. Therefore, the greater commitment of OHRQoL appears to be influenced by the etiology of Class III, and not by treatment plan.
Total Ankle Arthroplasty Survival and Risk Factors for Failure
Authors: Escudero Mario I. , Le Vu , Barahona Maximiliano , Symes Michael , Wing Kevin , Younger Alastair , Veljkovic Andrea , Penner Murray 
Published: June 2019

Background: Total ankle arthroplasty (TAA) is an increasingly selected treatment for end-stage ankle arthritis; however, failure and revision of the tibial and talar components remains an issue. Although multiple risk factors have been shown to contribute to early component revision, no study has looked at combining such risk factors into a predictive model that could potentially decrease revision rates and improve implant survival. This study aimed to develop a predictive model for TAA failure based on patient characteristics, patient-reported outcomes (PROs), and immediate postoperative radiographs. Methods: A retrospective review of a single-site ankle arthritis database was conducted. All patients with current-generation ankle replacements including the Hintegra and Infinity prostheses implanted between 2004 and 2015 and with complete postoperative radiographs taken between 6 and 12 weeks postoperatively were included. Eight coronal and sagittal radiographic parameters were assessed and performed twice by 2 independent orthopedic surgeons on included TAAs. These radiographic parameters were then analyzed in association with patient demographics and PRO. Advanced statistical methods including survival analysis were used to construct a predictive model for TAA survival. A total of 107 patients were included and analyzed with a median clinical follow-up of 49 months (minimum 24 months). Results: A predictive model was created, with 4 parameters identified as being statistically associated with TAA metal-component revision: diabetes mellitus, poor baseline Ankle Osteoarthritis Scale (AOS) score, excessively dorsiflexed talar component, and an anteriorly/posteriorly translated talus relative to the tibial axis. The presence of 3 parameters predicted TAA survival of 0.60 whereas presence of all 4 parameters predicted survival of only 0.13 in the period studied. Conclusion: Our predictive model is based on a combination of patient factors, PROs, and radiographic TAA alignment. We believe it can be used by surgeons to predict failure in their TAA patients, thereby optimizing postoperative outcomes by improving patient selection and modifiable outcome-specific parameters. Level of Evidence: Level III, retrospective cohort study using prospectively collected data.
Patients at Risk for Exceeding CJR Cost Targets After Total Ankle Arthroplasty
Authors: Goltz Daniel E. , Ryan Sean P. , Howell Claire B. , Bolognesi Michael P. , Seyler Thorsten M. , Adams Samuel B. 
Published: June 2019

Background: The Comprehensive Care for Joint Replacement (CJR) model includes total ankle arthroplasty (TAA), under which a target reimbursement is established. Whether this reimbursement is sufficient to cover average cost remains unknown. We hypothesized that a substantial number of TAAs still exceed cost targets, and that risk factors associated with exceeding the target cost could be identified preoperatively. Methods: Two hundred two primary TAAs performed at a single tertiary referral center under the CJR model from June 2013 to May 2017 were retrospectively reviewed. Patient demographics, comorbidities, outcomes, and costs were extracted from the electronic medical record using a validated structured query language (SQL) algorithm. A comparison cohort of 2084 CJR total hip arthroplasty (THA) and total knee arthroplasty (TKA) cases performed during the same period was also reviewed. Results: Twenty TAAs (10%) exceeded the target cost of care, significantly fewer than CJR THAs/TKAs (29%) performed during the same period ( P < .0001). These patients did not differ significantly in age, sex, body mass index, number of Elixhauser comorbidities, or the American Society of Anesthesiologists score. The average cost for these patients was $17 338 higher than those who did not exceed the target cost, and they were less likely to be married or have a partner (45% vs 79%, P = .001). Non-Caucasian status also reached significance ( P < .0001). Those exceeding the target cost had a significantly longer length of stay (2.6 vs 1.5 days, P < .0001) and were more likely to be discharged to either skilled nursing or a rehabilitation facility (60% vs 1%, P < .0001). Conclusion: Even high-volume TAA centers still exceed target costs in up to 10% of cases, with length of stay, discharge location, and readmissions driving many of these events. Potential risk factors for excess cost include marital/partner status and non-Caucasian ethnicity, but further work is needed to clarify their effects and whether other risk factors exist. Level of Evidence: Level III, comparative study.
Psychological resilience is linked to motor strength and gait endurance in early multiple sclerosis
Authors: Klineova Sylvia , Brandstadter Rachel , Fabian Michelle T , Sand Ilana Katz , Krieger Stephen , Leavitt Victoria M , Lewis Christina , Riley Claire S , Lublin Fred , Miller Aaron E , Sumowski James F 
Published: June 2019

Background: Psychologically resilient persons persist despite obstacles and bounce back after adversity, leading to better outcomes in non-neurologic populations. It is unknown whether psychological resilience relates to objective functional outcomes in multiple sclerosis (MS). Objective: To determine whether psychological resilience explains differential objective cognitive and motor functioning in persons with early MS. Methods: Psychological resilience was assessed in 185 patients with early MS and 50 matched healthy controls with the Connors-Davidson Resilience Scale (CDRS-10). Subjects completed the MS Functional Composite (MSFC) and a comprehensive neurobehavioral evaluation. Correlations assessed links between CDRS-10 and MSFC, motor indices (Total, Fine Motor, Gross Motor), and cognitive indices (Total, Cognitive Efficiency, Memory). Results: Higher CDRS-10 among patients was linked to better MSFC and motor outcomes (but not cognition), with the most robust relationships for gross motor function (grip strength, gait endurance). Findings were independent of mood and fatigue. CDRS-10 was unrelated to MS disease burden. CDRS-10 was also specifically linked to motor outcomes in healthy controls. Conclusion: Functional outcomes vary across persons with MS, even when disease burden and neurologic disability are low. These findings identify high psychological resilience as a non-disease-specific contributor to motor strength and endurance, which may explain differential outcomes across patients.
Apathy and Disinhibition Related to Neuropathology in Amnestic Versus Behavioral Dementias
Authors: Borges Letizia G. , Rademaker Alfred W. , Bigio Eileen H. , Mesulam M-Marsel , Weintraub Sandra 
Published: June 2019

Objectives: Investigating the frequency of apathy and disinhibition in patients clinically diagnosed with dementia of the Alzheimer type (DAT) or behavioral variant frontotemporal dementia (bvFTD) with neuropathology of either Alzheimer disease (AD) or frontotemporal lobar degeneration (FTLD). Methods: Retrospective data from 887 cases were analyzed, and the frequencies of apathy and disinhibition were compared at baseline and longitudinally in 4 groups: DAT/AD, DAT/FTLD, bvFTD/FTLD, and bvFTD/AD. Results: Apathy alone was more common in AD (33%) than FTLD (25%), and the combination of apathy and disinhibition was more common in FTLD (43%) than AD (14%; P < .0001). Over time, apathy became more frequent in AD with increasing dementia severity (33%-41%; P < .006). Conclusions: Alzheimer disease neuropathology had the closest association with the neuropsychiatric symptom of apathy, while FTLD was most associated with the combination of apathy and disinhibition. Over time, the frequency of those with apathy increased in both AD and FTLD neuropathology.
High-flow nasal cannula oxygen therapy to treat acute respiratory failure in patients with acute exacerbation of idiopathic pulmonary fibrosis
Authors: Vianello Andrea , Arcaro Giovanna , Molena Beatrice , Turato Cristian , Braccioni Fausto , Paladini Luciana , Vio Stefania , Ferrarese Silvia , Peditto Piera , Gallan Federico , Saetta Marina 
Published: June 2019

Background: Some patients with idiopathic pulmonary fibrosis (IPF) develop acute exacerbation (AE-IPF) leading to severe acute respiratory failure (ARF); despite conventional supportive therapy, the mortality rate remains extremely high. The aim of this study was to assess how a treatment algorithm incorporating high-flow nasal cannula (HFNC) oxygen therapy affects the short-term mortality of patients with AE-IPF who develop ARF. Method and design: A retrospective cohort analysis was conducted. Patients and interventions: The study consisted of 17 patients with AE-IPF admitted to a respiratory intensive care unit (RICU) for ARF managed using a treatment algorithm incorporating HFNC. The outcome measure was mortality rate during their stay in the RICU. Results: Implementation of the treatment algorithm led to a successful outcome in nine patients and to a negative one in eight patients (47.1%) who died within 39 days of being admitted to the RICU. The survival rate was 70.6% (±0.1 %) at 15 days, 52.9% (±0.1%) at 30 days, 35.3% (±0.1%) at 90 days, and 15.6% (±9.73 %) at 365 days. Overall, 4 out of 10 patients who did not respond to conventional oxygen therapy showed a satisfactory response to HFNC. Conclusions: Short-term mortality fell to below 50% when a treatment algorithm incorporating HFNC was implemented in a group of patients with AE-IPF admitted to a RICU for ARF. Patients not responding to conventional oxygen therapy seemed to benefit from HFNC. The reviews of this paper are available via the supplementary material section.
Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences
Authors: Scheltema Matthijs J. , O’Brien Tim J. , van den Bos Willemien , de Bruin Daniel M. , Davalos Rafael V. , van den Geld Cees W.M. , Laguna Maria P. , Neal Robert E. , Varkarakis Ioannis M. , Skolarikos Andreas , Stricker Phillip D. , de Reijke Theo. M. , Arena Christopher B. , de la Rosette Jean 
Published: June 2019

Background: At present, it is not possible to predict the ablation zone volume following irreversible electroporation (IRE) for prostate cancer (PCa). This study aimed to determine the necessary electrical field threshold to ablate human prostate tissue in vivo with IRE. Methods: In this prospective multicenter trial, patients with localized PCa were treated with IRE 4 weeks before their scheduled radical prostatectomy. In 13 patients, numerical models of the electrical field were generated and compared with the ablation zone volume on whole-mount pathology and T2-weighted magnetic resonance imaging (MRI) sequences. Volume-generating software was used to calculate the ablation zone volumes on histology and MRI. The electric field threshold to ablate prostate tissue was determined for each patient. Results: A total of 13 patients were included for histological and simulation analysis. The median electrical field threshold was 550 V/cm (interquartile range 383–750 V/cm) for the software-generated histology volumes. The median electrical field threshold was 500 V/cm (interquartile range 386–580 V/cm) when the ablation zone volumes were used from the follow-up MRI. Conclusions: The electrical field threshold to ablate human prostate tissue in vivo was determined using whole-mount pathology and MRI. These thresholds may be used to develop treatment planning or monitoring software for IRE prostate ablation; however, further optimization of simulation methods are required to decrease the variance that was observed between patients.
A case of Crimean-Congo haemorrhagic fever imported in Greece: Contact tracing and management of exposed healthcare workers
Authors: Maltezou Helena C , Papa Anna , Ventouri Sarantoula , Tseki Charikleia , Pervanidou Danai , Pavli Androula , Panagopoulos Periklis , Markatou Philothei , Gavana Elpida , Maltezos Efstratios 
Published: June 2019

Background: Nosocomial transmission is a major mode of infection of Crimean-Congo haemorrhagic fever (CCHF). In May 2018, a patient with CCHF was hospitalised in Greece. Objective: Our aim was to present the management of healthcare workers (HCWs) to the CCHF case. Methods: Contact tracing, risk assessment and follow-up of exposed HCWs were performed. Testing (RT-PCR and/or serology) was offered to contacts. Post-exposure prophylaxis (PEP) with ribavirin was considered for high-risk exposures. Results: Ninety-one HCWs were exposed to the case. Sixty-six HCWs were grouped as high-risk exposures. Ribavirin PEP was offered to 29 HCWs; seven agreed to receive prophylaxis. Forty-one HCWs were tested for CCHF infection; none was found positive. Gaps in infection control occurred. Discussion: CCHF should be considered in patients with compatible travel history and clinical and laboratory findings. Early clinical suspicion and laboratory confirmation are imperative for the implementation of appropriate infection control measures. Ribavirin should be considered for high-risk exposures. Infection control capacity for highly pathogenic agents should increase.