bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the relationship between psoriasis and vitamin D
Authors: Kiełczewska Aleksandra , Szcześniak Grzegorz , Kiełczewska Anna 
Published: November 2024

Introduction and purpose: Psoriasis is a chronic, inflammatory skin condition that affects millions of individuals worldwide. Recent research has suggested a potential link between psoriasis and vitamin D deficiency. This review paper aims to examine the existing literature on the relationship between psoriasis and vitamin D, exploring the potential role of vitamin D in the pathogenesis and management of this debilitating skin disorder.
Materials and method: An extensive examination of articles published in scientific journals was carried out through online research platforms PubMed and Google Scholar. We searched articles by entering keywords in appropriate configuration: “psoriasis”, “vitamin D”, “obesity”.
Description of the state of knowledge: Emerging research has identified a connection between vitamin D and the development of various skin conditions, including psoriasis. Consistent findings have shown a significant association between low vitamin D levels and the presence of psoriasis. Furthermore, due to vitamin D's influence on the proliferation and maturation of keratinocytes, it has become an important local treatment option for managing psoriasis.
Summary: Although there is no clear consensus on whether sufficient dietary vitamin D or oral vitamin D supplements effectively treat psoriasis, the available evidence is still inconclusive. However, healthcare providers like nutritionists should consider recommending general vitamin D supplementation for populations at high risk of vitamin D deficiency, such as those with psoriasis or obesity.
Combining elements of a layering composite system with a universal to simplify manufacturing of demanding anterior restorations
Authors: Kouros Pantelis 
Published: November 2024

This article describes a layering alternative that simplifies procedures when using layering techniques combined with a silicone key to aesthetically restore incisor teeth. Replacement of enamel shades of a layering system with a universal shade composite that produces structural colour, allows material manipulation in thicker layers, with no adverse influence on the optical properties of the restoration, thus accelerating and facilitating the clinical procedure. CPD/Clinical Relevance: A technique to simplify the use of layering strategies for incisor teeth.
So, you want to get published? Here's how!
Authors: Bonsor Stephen J 
Published: November 2024

For many talented clinicians who wish to share their cases applying the evidence base to support decision making or perhaps write a narrative review of the literature, there may be a knowledge gap in how they approach such a project, which may present a significant barrier. This article explains how a peer-reviewed paper, such as one submitted to Aesthetic Journal, is conceived, developed and written. It offers many useful tips and advice on how the paper should be presented in terms of language, style of writing and structure. It also explains the post-submission phase, including the peer-review process and the run-up to publication. CPD/Clinical Relevance: The publication of high-quality clinical cases and reviews has an essential educational role for other colleagues, yet writing to a sufficiently high standard to be published in a peer-reviewed journal may be a barrier.
Mitigating hemoglobin‐induced nephropathy: ApoHb‐hp protection of podocytes
Authors: Lucas Daniela , Munoz Carlos , O'Boyle Quintin , Pires Ivan S. , Palmer Andre F. , Cabrales Pedro 
Published: November 2024

AbstractThis study investigates hemoglobin (Hb)‐induced kidney injury and the protective role of the ApoHemoglobin‐Haptoglobin (ApoHb‐Hp) complex against heme and Hb damage. Hb facilitates oxygen (O2) delivery but poses challenges outside red blood cells (RBCs) due to toxic Hb and heme mechanisms. These are managed by binding to serum proteins like Haptoglobin (Hp) and Hemopexin (Hpx). During hemolysis, depletion of Hp and Hpx leaves tissues vulnerable to Hb and heme. To address this, we developed the ApoHb‐Hp complex, based on Apohemoglobin, which is produced by removing heme from Hb, conjugated with Hp. This complex acts as a dual scavenger for Hb and heme, preventing tissue damage. Our findings demonstrate that ApoHb‐Hp significantly protects MPC5 podocytes from Hb‐induced damage. Fluorescent staining showed a higher percentage of nephrin‐positive cells in the ApoHb‐Hp group, and MTT assays revealed enhanced cell viability compared to Hb alone. Additionally, ApoHb‐Hp reduced reactive oxygen species (ROS) production, with the Hb group exhibiting significantly elevated ROS levels. The ApoHb‐Hp complex mitigated the depletion of protective mechanisms, as shown by significant increases in superoxide dismutase (SOD) and glutathione (GSH). Moreover, ApoHb‐Hp treatment reduced the activation of the NLRP3 inflammasome signaling pathway and inflammatory cytokines IL‐1β and IL‐18. These findings underscore the therapeutic potential of ApoHb‐Hp in mitigating Hb‐induced renal damage by preserving podocyte viability and reducing oxidative stress. Overall, ApoHb‐Hp maintained protective mechanisms depleted otherwise by Hb. These findings highlight ApoHb‐Hp's potential as a therapeutic agent against Hb‐induced renal damage, offering insights into its mechanisms and implications for treating conditions involving hemolysis.
Metric lines in the jet space
Authors: Bravo-Doddoli Alejandro 
Published: November 2024

Abstract
In the realm of sub-Riemannian manifolds, a relevant question is: what are the metric lines (isometric embedding of the real line)? The space of

k

k

-jets of a real function of one real variable

x

x

, denoted by

J

k

(

R
,
R

)

{J}^{k}\left({\mathbb{R}},{\mathbb{R}})

, admits the structure of a Carnot group. Every Carnot group is sub-Riemannian manifold, so is

J

k

(

R
,
R

)

{J}^{k}\left({\mathbb{R}},{\mathbb{R}})

. This study aims to present a partial result about the classification of the metric lines within

J

k

(

R
,
R

)

{J}^{k}\left({\mathbb{R}},{\mathbb{R}})

. The method is to use an intermediate three-dimensional sub-Riemannian space

R

F

3

{{\mathbb{R}}}_{F}^{3}

lying between the group

J

k

(

R
,
R

)

{J}^{k}\left({\mathbb{R}},{\mathbb{R}})

and the Euclidean space

R

2

{{\mathbb{R}}}^{2}

.
Weighted Hardy-Adams inequality on unit ball of any even dimension
Authors: Wang Xumin 
Published: November 2024

Abstract
In this study, we obtain the weighted Hardy-Adams inequality of any even dimension

n
≥
4

n\ge 4

. Namely, for

u
∈

C

0

∞

(

B

n

)

u\in {C}_{0}^{\infty }\left({{\mathbb{B}}}^{n})

with

∫

B

n

∣

∇

n

2

u
∣

2

d
x
−

∏

k
=
1

n
⁄
2

(

2
k
−
1

)

2

∫

B

n

u

2

(

1
−

∣
x
∣

2

)

n

d
x
≤
1
,

\mathop{\int }\limits_{{{\mathbb{B}}}^{n}}{| {\nabla }^{\frac{n}{2}}u| }^{2}{\rm{d}}x-\mathop{\prod }\limits_{k=1}^{n/2}{\left(2k-1)}^{2}\mathop{\int }\limits_{{{\mathbb{B}}}^{n}}\frac{{u}^{2}}{{\left(1-{| x| }^{2})}^{n}}{\rm{d}}x\le 1,

then the following Hardy-Adams inequalities hold:

∫

B

n

exp

2

2
−
n
−
ϑ

β

0

n

2

,
n

(

u

φ

ϑ

)

2

(

1
−

∣
x
∣

2

)

2
ϑ
+
n
−
4

d
x
≤

C

n
,
ϑ

,

ϑ
∈

3
−
n

2

,
0

\begin{array}{r}\mathop{\displaystyle \int }\limits_{{{\mathbb{B}}}^{n}}\exp \left({2}^{2-n-{\vartheta }}{\beta }_{0}\left(\frac{n}{2},n\right){\left(u{\varphi }_{{\vartheta }})}^{2}\right){(1-{| x| }^{2})}^{2{\vartheta }+n-4}{\rm{d}}x\le {C}_{n,{\vartheta }},\hspace{0.33em}\hspace{0.33em}{\vartheta }\in \left(\frac{3-n}{2},0\right]\end{array}

and

∫

B

n

Φ

2

2

2
−
n
−
ϑ

β

0

n

2

,
n

(

u

φ

ϑ

)

2

(

1
−

∣
x
∣

2

)

2
ϑ
+
n
−
4

d
x
≤

C

n
,
ϑ

,

ϑ
∈

(

2
−
n
,

3
−
n

2

]

,

\mathop{\int }\limits_{{{\mathbb{B}}}^{n}}{\Phi }_{2}\left({2}^{2-n-{\vartheta }}{\beta }_{0}\left(\frac{n}{2},n\right){\left(u{\varphi }_{{\vartheta }})}^{2}\right){(1-{| x| }^{2})}^{2{\vartheta }+n-4}{\rm{d}}x\le {C}_{n,{\vartheta }},\hspace{0.33em}\hspace{0.33em}{\vartheta }\in \left(2-n,\frac{3-n}{2}\right],

where

Φ

2

(

t

)

=

e

t

−

∑

1

j
=
0

t

j

j
!

{\Phi }_{2}\left(t)={e}^{t}-\mathop{\sum ^{1}}\limits_{j=0}\frac{{t}^{j}}{j\&#x0021;}

,

φ

ϑ

(

x

)

=

2

1
−

∣
x
∣

2

n
+
ϑ
−
2

2

{\varphi }_{{\vartheta }}\left(x)={\left(,\frac{2}{1-{| x| }^{2}}\right)}^{\tfrac{n+{\vartheta }-2}{2}}

and

C

n
,
ϑ

{C}_{n,{\vartheta }}

is a positive constant independent of

u

u

. The crucial method in this article is borrowed from Lu and Yang [Adv. Math. 319 (2017)] and Li, Lu and Yang [Adv. Math. 333 (2018)]. We also apply set level method which was first developed by Lam and Lu [J. Diff. Equa. 255 (2013)]. The new ingredient here is to utilize the relationship between

Δ

H

{\Delta }_{{\mathbb{H}}}

and the Laplace-Beltrami operator

Δ

ϑ

{\Delta }_{{\vartheta }}

, where

Δ

ϑ

{\Delta }_{{\vartheta }}

is developed by Liu and Peng [Indiana Univ. Math. J. 3 (2009), 1457–1492]. Furthermore, the Hardy-Adams inequality in this article is the weighted version of the result of Li et al. [Adv. Math. 333 (2018), 350–385].
Correlation analysis of AVPR1a and AVPR2 with abnormal water and sodium and potassium metabolism in rats
Authors: Sun Kun , Qiu Yingzhu , Sun Yao 
Published: November 2024

Abstract
In clinical practice, an increasing number of patients exhibit concurrent cardiac and renal dysfunction, known as “cardiorenal syndrome,” where each condition exacerbates the other, resulting in poorer patient prognosis. Fluid and sodium retention can lead to excessive fluid overload in the body; therefore, correcting fluid and sodium metabolic disorders is crucial for alleviating patient symptoms. This study was to investigate the abnormalities in water and sodium metabolism, as well as the expression levels of arginine vasopressin receptor 1a (AVPR1a) and arginine vasopressin receptor 2 (AVPR2), in a rat model of chronic renal failure–chronic heart failure (CRF–CHF). One hundred male Sprague-Dawley rats were randomly assigned into four groups: the CG group (normal feeding), the CRF group (3/4 nephrectomy using a “two-step surgical method”), the CHF group (subcutaneous injection of isoproterenol at 100 mg/kg), and the CRF–CHF group (3/4 nephrectomy followed by a subcutaneous injection of isoproterenol at 100 mg/kg 1 week later). 4 weeks post-surgery, urine and blood samples were collected to measure 24 h urinary protein, sodium, and potassium levels. Serum creatinine (SCr) and blood urea nitrogen (BUN) levels were determined using assay kits. Left ventricular end diastolic pressure (LVEDP) and left ventricular systolic pressure (LVSP) were measured via left ventricular catheterization. The heart was weighed to calculate the left ventricular weight to body weight ratio (LVW/BW). The renal cortex and medulla were isolated to assess the relative mRNA and protein expression levels of AVPR1a and AVPR2. Compared to the CG group, the CRF and CRF–CHF groups exhibited significantly elevated levels of 24 h urinary protein, SCr, BUN, and relative expression levels of AVPR1a and AVPR2 in the renal cortex and medulla. The CHF and CRF–CHF groups showed significant increases in LVEDP and LVW/BW (P < 0.05). Additionally, compared to the CG group, the other three groups had significantly increased urinary sodium and blood potassium levels, and significantly decreased urinary potassium and blood sodium levels (P < 0.05). Compared to the CRF and CHF groups, the CRF–CHF group exhibited significantly higher levels of 24 h urinary protein, SCr, BUN, and relative expression levels of AVPR1a and AVPR2 in the renal cortex and medulla, along with significantly increased LVEDP and LVW/BW, significantly reduced LVSP, significantly increased urinary sodium and blood potassium levels, and significantly decreased urinary potassium and blood sodium levels (P < 0.05). Rats with CRF–CHF experienced exacerbated renal and cardiac failure, characterized by significant disturbances in water and sodium metabolism and abnormal expression of AVPR1a and AVPR2.
Effectiveness of a Pop-Up Story-Based Program for Developing Environmental Awareness and Sustainability Concepts among First-Grade Elementary Students
Authors: Mohamed Dalia Abdelwahed , Ali Asma Margeni Hussien 
Published: November 2024

Abstract
The study aims to assess the effectiveness of a pop-up story-based program in fostering environmental awareness and sustainability among first-grade elementary students. Using a quasi-experimental design, the study included experimental and control groups, each consisting of 56 students, randomly assigned to two groups: 28 in the experimental group and 28 in the control group. The experimental group participated in a 12-session program on environmental awareness and sustainability. After confirming the test’s validity, reliability, and appropriate difficulty and discrimination indices, both groups took a pictorial test covering four key concepts: water and air pollution, recycling, sustainable agriculture, and manufacturing. The results showed statistically significant differences at the 0.05 level between the post-test scores of the control and experimental groups regarding environmental awareness and sustainability concepts, in favor of the experimental group. This demonstrates the effectiveness of the pop-up story-based program in enhancing environmental awareness and sustainability concepts among first-grade students. The study recommends integrating environmental awareness and sustainability topics into teacher training programs at education colleges.
Study on the influence mechanism of land use on carbon storage under multiple scenarios: A case study of Wenzhou
Authors: Quan Wei , Huang Xuankai , Xu Gang , Hao Jun , Lv Kangting , Jiang Xiaomin 
Published: November 2024

Abstract
Based on the perspective of conflict of interest between low-carbon ecology and economic and social development, this study explores the change mechanism of land use cover change (LUCC) and carbon storage (CS) in the context of “Dual-Carbon” goal and territorial spatial ecological governance, which is of great significance to optimize the construction path of “Dual-Carbon” goal and formulate low-carbon, ecological, high-quality, and sustainable economic and social policies in the urban areas. An integrated framework based on the System Dynamics model, the Patch Generation Land Simulation model, and the Integrated Valuation of Ecosystem Services and Trade-offs model was constructed to dynamically simulate the LUCC demand and CS of Wenzhou under four scenarios in 2035, and to analyze the spatial evolution mechanisms of LUCC and CS. The main results of the study show that in the Natural Development Scenario (NDS) and High-speed Urbanization Scenario (HUS), the expansion mechanism is similar, and the area of woodland decreases greatly, which is mainly caused by the rapid expansion of construction land and cultivated land. Under Low-carbon and High-quality Development Scenario (LHDS) and Ecological Safety Governance Scenario (ESGS), woodland and grassland increased significantly, mainly because low-carbon and ecological governance policies strengthened ecological land protection and limited construction land control. By 2035, the prediction results show that LHDS has the highest CS (2.231 × 105 kt), followed by ESGS (2.226 × 105 kt), NDS (2.191 × 105 kt), and HUS (2.142 × 105 kt). The range of increase and decrease was 0.189, −0.149, −1.676, −3.692%, and only in LHDS, CS increased by 42.05 kt. Therefore, in order to achieve the “Dual-Carbon” goal, Wenzhou needs to prioritize the combination of LHDS and ESGS to formulate relevant policies.
Conditional Right to Child Education in Nigeria: Punishing the Child for the Parents’ Sins
Authors: Jimoh Mujib 
Published: November 2024

Abstract
The question this paper seeks to answer is: can the refusal of parents to pay taxes be the basis for the State to deny their child’s right to education? In ISH-16, the High Court of Lagos State, Nigeria, answered the question in the affirmative. This paper seeks to answer otherwise. It argues that human rights theory cannot support the Court’s reasoning. However, because the paper is more legal than philosophical, it neither attempts to give a ‘full’ philosophical account of human rights nor discusses the ‘best’ theory that can support its thesis. Instead, the paper adopts Williams’ Phenomenological Conclusions on human rights and the Kin Punishment Theory to assert its claim. First, the paper argues that from Williams’ Phenomenological Conclusions that P (a State) which owes Y (the child) X (the right to education) and must procure X for Y, the parents’ duty to pay taxes to the State finds no place in those conclusions. Second, the paper posits that the Kin Punishment Theory, a rule of customary international law, prohibits the kin – no matter how close or grave the crime is – from being punished for the sin of a close relative. Human rights theory considers the desert basis for punishing the kin of the offender to be ‘zero.’ The paper lays three premises: (1) that human rights attach to personhood; (2) that a child is a separate person who has a legal personality since human rights law has detached the child from patria potestas; and (3) that requiring a condition (tax payment) from the parents before their child can enjoy the right to education is a punishment. From these premises, the paper concludes that punishing the child (by denying them their right to education) because their parents (other persons) refuse to pay tax violates the Kin Punishment Theory.
Psychological and behavioral assessments in girls with idiopathic central precocious puberty
Authors: Uthayo Warisa , Chunin Hathaichanok , Sudnawa Khemika K. , Arunyanart Wirongrong , Phatarakijnirund Voraluck 
Published: November 2024

Abstract

Objectives
Idiopathic central precocious puberty (iCPP) is the most common cause of precocious puberty in girls. However, research on the psychological outcomes of iCPP girls is limited. To evaluated the psychological characteristics in iCPP girls in comparison to prepubertal girls throughout the first diagnosis and six-month follow-up period.

Methods
Eighty-five girls, age 6–8 years, and their caregivers were enrolled to the prospective cohort study. Three Thai-standardized questionnaires were used as psychological assessment tools, including Children’s Depression Inventory (CDI), Parent Screen for Child Anxiety Related Disorders (SCARED) and Parent-Strengths and Difficulties Questionnaire (SDQ).

Results
Forty-six iCPP and 39 prepuberty girls were enrolled at baseline. No significant differences in psychological and behavioral problems between iCPP and prepuberty girls. However, the iCPP group exhibited a significantly higher proportion of “risk and problem” for emotional problems compares to the prepuberty group (7 vs. 0, p=0.01) while the prepuberty group exhibits the significantly proportion of “risk” for peer problems (6 vs. 0, p=0.007). At baseline, twelve percent of iCPP girls exhibited depression and mean CDI score was 8.1 ± 7.2 and 3.7 ± 2.3 (p=0.007) in iCPP and prepuberty group, respectively. At the 6-month follow-up, there was no significant difference in psychological outcomes between two groups.

Conclusions
There were no significant differences in psychological and behavioral problems in iCPP girls compared to prepubertal girls. However, the higher prevalence of emotional problems and depression observed in iCPP girls constitutes significant psychological issues that necessitate close monitoring.
Development of Customized Project Management Methodology for the Implementation of Online Archives Exhibitions: Insights and Evaluation from a Research and Development Organization
Authors: P. Arumugam , Thomas Temin , R. Rega 
Published: November 2024

Abstract
This study explores the development of a customized project management methodology tailored for the implementation of online archives exhibitions, offering insights and evaluation derived from a research and development organization. Recognizing the distinctive requirements of such projects, the research investigates the design and application of a specialized project management approach. Through a comprehensive analysis, this study presents key insights into the methodology’s efficacy and evaluates its impact within the unique context of a research and development setting. The findings contribute valuable perspectives to the evolving field of project management, particularly in the realm of digital exhibition development within innovative organizational environments.
The intrinsic dielectric properties of Mediterranean bio-composites
Authors: AL-Oqla Faris M. , Nawafleh Nashat 
Published: November 2024

Abstract
The environment is seriously threatened by the growing use and disposal of technological products since most of them include non-biodegradable components. One approach to reduce environmental impact of electronic devices is to use biodegradable electronic components derived from natural fibers like protein and cellulose. Actually, a lot of research has been done on the viability of producing electronic components out of materials obtained from natural fibers. Their inclusion of several changeable functional categories is another benefit. Dielectric materials are one of the several necessary and commonplace parts of technical devices. A thorough study on the varieties of natural fibers used to make dielectric materials and their electrical properties would be beneficial in selecting the appropriate fibers and conditions for certain applications. To make full use of new natural composite materials in growing sectors, their electric properties have to be examined. However, along with polypropylene, four different kinds of natural lignocellulosic fibers will be discussed in this work: black pepper, sumac, pomegranate, and lemon – as case studies. In specific, over a frequency range of 1 KHz to 4 MH, the AC conductivity and dielectric constant of the produced samples were measured using the method of parallel plate capacitors. After that, given the performance of sisal fibers, a comparison between them and a sisal natural fiber (a non-Mediterranean variety) will be made.
Making (and de-making) technological risk in banal spaces and speculative language
Authors: Jethani Suneel Kumar 
Published: November 2024

In this paper I provide a framework for enhancing seemingly objective approaches to AI risk assessment in a way that doesn't just see risk as only scaling vertically, levelling up through thresholds and tolerances(intensities). It draws on Raqs Media Collective’s An Infra-vocabulary for Capital (2023-2024) and considers how the work can be adapted to imagine horizontal formations of risk (accumulations) by using language and naming resulting in different apertures and resolutions on the relations that hold that risk together as a latent force in operational space.