bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of Seizure-Manifested Hartnup Disorder Case Induced by Novel Mutations in SLC6A19
Authors: Zhu Yanmei , Chen Li , He Jia , Chen Yan , Gou Haiyan , Ma Long , Qu Youyang , Liu Yu , Wang Di , Zhu Yulan 
Published: March 2018

AbstractAimThe aim of the study is to investigate a variation in the gene SLC6A19 in a female patient with Hartnup disorder manifested only by seizure.MethodsDNA samples collected from the patient and her parents were analyzed and twelve exons of the SLC6A19 gene were amplified and sequenced.ResultsWe found c.47C>T and c.1522G>A mutations in the gene SLC6A19 belonging to the patient, which are missense mutations inherited from her parents. The c.47C>T mutation is from her father and c.1522G>A is inherited from her mother. The parents are both heterozygous healthy carriers.ConclusionTwo novel mutations of the SLC6A19 gene are revealed in the female patient with Hartnup disorder, exhibiting no typical dermatologic problems, but having dramatic neurological symptoms.
Decoding Byzantine ekphraseis on works of art. Constantine Manasses’s description of earth and its audience
Authors: Foskolou Vicky 
Published: March 2018

Abstract
The study deals with ekphraseis on works of art and poses the question as to how far these texts can be a reliable source for the study or even the reconstruction of the artefacts they describe. Based on reception theory and readerresponse criticism, in the paper is proposed that as every text, byzantine ekphraseis on artworks presuppose an audience or readership, i. e. the one the author had in mind and on the basis of which he encoded his message. In order to decode this message and by extension to extract any information about the described works of art we must aim to discover their “intended reader”, and identify his or her “horizon of expectations. This proposal is tested in the study of a well known piece of this kind, Manasses’s description of a mosaic floor with a depiction of Earth. The author’s dialogue with the earlier tradition of ekphraseis, his readership’s “horizon of expectations” combined with historical facts, allow us to suppose that Manasses is describing a composition with Xenia scenes and an asarotos motif (unswept floor) created in the early byzantine period and preserved in the Great Palace of Constantinople up to the twelfth century.
The Global Economy in the 21st Century: Will the Trends of the 20th Century Continue?
Authors: Gomułka Stanisław 
Published: March 2018

AbstractThis paper compares three lists of basic ‘stylized facts’ of global economic growth and proposes a list of five ‘stylized trends’ that describe the main developments of the global economy in the 20th century. The author’s main purpose is to answer the question whether, in the light of the contemporary growth theory and demographic forecasts, these trends are likely to continue in the 21st century. Considering this theory, it is argued that the global economy rate of growth of the per capita gross domestic product (GDP) is likely to continue to be high in the first half of the current century, but decline significantly in the second half. This paper offers forecasts for the average growth rates during this century, and the levels by its end, of the per capita GDP for the technology frontier area (TFA) of the world, and for the countries outside the TFA. According to these forecasts, the strong divergence trend of the 19th and 20th centuries will be replaced by a strong convergence between the TFA and the other countries during the 21st century.
Studies on the flammability of polypropylene/ammonium polyphosphate and montmorillonite by using the cone calorimeter test
Authors: Hanna A.A. , Nour M.A. , Souaya E.R. , sherief M.A. , Abdelmoaty A.S. 
Published: March 2018

Abstract
Fire performance of polypropylene (PP) containing different percentages of ammonium polyphosphate (APP) with montmorillonite (Mt) or treated montmorillonite (MtT) was carried out by using the cone calorimeter test (CCT). Different samples from ammonium polyphosphate and montmorillonite were mixed with 90% polypropylene. The characterization of the prepared samples indicates that there is incorporation between the components of the samples. Heat release rate (HRR), peak heat release rate (PHRR), average heat release rate (Av-HRR), and time to ignition (TTI) of the samples were obtained from the cone calorimeter test. Also, the fire performance index (FPI) and the fire growth rate (FIGRA) were calculated. The interpretation of the curves and the parameters results from the cone calorimeter test which indicates that the addition of montmorillonite to APP increases its action as a flame retardant for PP. Moreover, the samples contain acid treatment montmorillonite showed an increase in the efficiency of ammonium polyphosphate when used. This result may be due to an increase in the SiO2 content by acid treatment.
Organic biocides hosted in layered double hydroxides: enhancing antimicrobial activity
Authors: Cruz Alejandra Santana , Flores Jorge , Guerra Roberto , Felipe Carlos , Lima Enrique 
Published: March 2018

AbstractSamples of layered double hydroxides containing carbonates as compensating anions were prepared by the urea method. These LDHs were used as hosts of anions coming from pipemidic and nalidixic acid. XRD results confirm that these anions were hosted in the interlayer space of LDHs. Further, from27Al NMR MAS characterization of an interaction between the brucite-like layers and anions was suggested. Then the hybrids LDHs were used as biocide ofSalmonella typhiandEscherichia coli. The release profile of pipemidic and nalidixic anions from hybrid LDHs occurs for periods as long as 3.5 hours. The free-organic acid LDHs were not able to killS.Typhi, neitherE.coli. In contrast, the hybrids LDHs eliminate almost completely bacteria within short times.
Bioassay-directed fractionation of a blood coagulation factor Xa inhibitor, betulinic acid from Lycopus lucidus
Authors: Tan Yin-Feng , Wang Qiong , Gong Jing-Wen , Zhang Xu-Guang , Li Yong-Hui , Zhang Jun-Qing , Li You-Bin 
Published: March 2018

AbstractThrombosis is a major cause of morbidity and mortality worldwide and plays a pivotal role in the pathogenesis of several cardiovascular disorders, including acute coronary syndrome, unstable angina, myocardial infarction, sudden cardiac death, peripheral arterial occlusion, ischemic stroke, deep-vein thrombosis, and pulmonary embolism. Anticoagulants, antiplatelet agents, and fibrinolytics can reduce the risks of these clinical events. Especially, the blood coagulation factor Xa (FXa) inhibitor is a proven anticoagulant. Promoting blood circulation, using traditional Chinese medicine (TCM), for the treatment of these diseases has been safely used for thousands of years in clinical practice. Therefore, highly safe and effective anticoagulant ingredients, including FXa inhibitors, could be found in TCM for activating the blood circulation. One FXa inhibitor, a pentacyclic triterpene (compound 1, betulinic acid) characterized by IR, MS and NMR analyses, was isolated from the ethyl acetate fraction of Lycopus lucidus by bioassay-directed fractionation. Compound 1 exhibited an inhibitory effect on FXa with IC50 25.05 μmol/L and reduced the thrombus weight in an animal model at 25-100 mg/kg. These results indicate that betulinic acid could be the potential for anticoagulant therapy.
Synthesis, characterization, in-vitro antimicrobial properties, molecular docking and DFT studies of 3-{(E)-[(4,6-dimethylpyrimidin-2-yl)imino]methyl} naphthalen-2-ol and Heteroleptic Mn(II), Co(II), Ni(II) and Zn(II) complexes
Authors: Chioma Festus , Ekennia Anthony C. , Osowole Aderoju A. , Okafor Sunday N. , Ibeji Collins U. , Onwudiwe Damian C. , Ujam Oguejiofo T. 
Published: March 2018

Abstract
Heteroleptic divalent metal complexes [M(L) (bipy)(Y)]•nH2O (where M = Mn, Co, Ni, and Zn; L = Schiff base; bipy = 2,2’-bipyridine; Y = OAc and n = 0, 1) have been synthesized from pyrimidine Schiff base ligand 3-{(E)-[(4,6-dimethylpyrimidin-2-yl)imino]methyl} naphthalen-2-ol, 2,2’-bipyridine and metal(II) acetate salts. The Schiff base and its complexes were characterized by analytical (CHN elemental analyses, solubility, melting point, conductivity) measurements, spectral (IR, UV-vis, 1H and 13C-NMR and MS) and magnetometry. The elemental analyses, Uv-vis spectra and room temperature magnetic moment data provide evidence of six coordinated octahedral geometry for the complexes. The metal complexes’ low molar conductivity values in dimethylsulphoxide suggested that they were non-ionic in nature. The compounds displayed moderate to good antimicrobial and antifungal activities against S. aureus, P. aeruginosa, E. coli, B. cereus, P. mirabilis, K. oxytoca, A. niger, A. flevus and R. Stolonifer. The compounds also exhibited good antioxidant potentials with ferrous ion chelation and, 1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assays. Molecular docking studies showed a good interaction with drug targets used. The structural and electronic properties of complexes were further confirmed by density functional theory calculations.
M-Polynomials and Topological Indices of Dominating David Derived Networks
Authors: Kang Shin Min , Nazeer Waqas , Gao Wei , Afzal Deeba , Gillani Syeda Nausheen 
Published: March 2018

Abstract
There is a strong relationship between the chemical characteristics of chemical compounds and their molecular structures. Topological indices are numerical values associated with the chemical molecular graphs that help to understand the physical features, chemical reactivity, and biological activity of chemical compound. Thus, the study of the topological indices is important. M-polynomial helps to recover many degree-based topological indices for example Zagreb indices, Randic index, symmetric division idex, inverse sum index etc. In this article we compute M-polynomials of dominating David derived networks of the first type, second type and third type of dimension n and find some topological properties by using these M-polynomials. The results are plotted using Maple to see the dependence of topological indices on the involved parameters.
Assessing theory with practice: an evaluation of two aspectual-semantic classification models of gerundive nominalizations
Authors: Fonteyn Lauren 
Published: March 2018

AbstractThis study present a corpus-based comparison of two aspectual-sematic classification models proposed in theoretical literature (unidimensional vs. bidimensional) by applying them to a set of nominal and verbal gerunds from the Modern English period. It (i) summarises the differences between unidimensional and bidimensional classification models and (ii) the potential problems associated with them. Despite the difficulties of studying semantic aspect in Present-day as well as historical data, this study will argue that, (iii) at least for deverbal nominalization patterns, it is possible to take a bidimensional approach and maintain a clear distinction between, on the one hand,aspectfeatures of the nominalized situation (stativity/dynamicity, durativity/punctuality, and telicity/atelicity), andtemporal boundednessof that situation. The question of which semantic classification model to use, then, is not so much one of which one is practically feasible in a corpus analysis, but rather which one is best suited to describe the attested variation. In order to determine the best model (in terms of parsimony and descriptive accuracy), (iv) the models were compared by means of ‘akaike weights’. To describe the variation between nominal and verbal gerunds in Early and Late Modern English, the bidimensional model outperformed the unidimensional one, showing that (v) the aspectual-semantic distinctions between Modern English nominal and verbal gerunds are a matter of bothaspectandtemporal boundedness.
Hybrid Discontinuous Galerkin Discretisation and Domain Decomposition Preconditioners for the Stokes Problem
Authors: Barrenechea Gabriel R. , Bosy Michał , Dolean Victorita , Nataf Frédéric , Tournier Pierre-Henri 
Published: March 2018

Abstract
Solving the Stokes equation by an optimal domain decomposition method derived algebraically involves the use of nonstandard interface conditions whose discretisation is not trivial. For this reason the use of approximation methods such as hybrid discontinuous Galerkin appears as an appropriate strategy: on the one hand they provide the best compromise in terms of the number of degrees of freedom in between standard continuous and discontinuous Galerkin methods, and on the other hand the degrees of freedom used in the nonstandard interface conditions are naturally defined at the boundary between elements. In this paper, we introduce the coupling between a well chosen discretisation method (hybrid discontinuous Galerkin) and a novel and efficient domain decomposition method to solve the Stokes system. We present the detailed analysis of the hybrid discontinuous Galerkin method for the Stokes problem with nonstandard boundary conditions. The full stability and convergence analysis
of the discretisation method is presented, and the results are corroborated by numerical experiments.
In addition, the advantage of the new preconditioners over more classical choices is also supported by numerical experiments.
An Autonomous Residential Smart Distribution Board: A Panacea for Demand Side Energy Management for Non-Smart Grid Networks
Authors: Olakanmi Oladayo O. , Adetoyi Oluyemi , Fajemisin Oluwafemi 
Published: March 2018

Abstract
Despite the benefits of demand response in energy management, the non-existence of its key concepts; dynamic pricing and smart grid, in some countries makes its impracticable in these countries, therefore making energy management unattainable for their consumers. This paper proposed a Smart Distribution Board (SDB) using a priority model for energy management in non-smart grid network. An historical consumption signatures of user’s loads were used to develop a priority model for load units of the SDB. Performance comparison was carried out between the SDB and a conventional Distribution Board which has no level of intelligence. Results obtained indicated that the SDB correctly emulated the energy usage pattern of users, thereby ensuring load preference is maximally satisfied autonomously within a limited budgeted energy and period.
VP-fronting: Movement vs. dislocation
Authors: Ott Dennis 
Published: March 2018

AbstractWhile VP-fronting in English has various properties that are generally taken to be hallmarks of$$\overline A $$-movement, other properties of the construction militate against an analysis in terms of displacement of VP to the clausal periphery. Such an analysis falls short of providing principled answers to the questions of why the trace of VP-fronting must be nominal, why certain kinds of morphological mismatches between the fronted VP and its trace are possible, why fronting of remnant VPs is impossible, and others. This article proposes an analysis of English VP-fronting – plausibly extending to English ’topicalization’ in general – based on the observation that the construction shares these non-movement properties with left-dislocation of VP in German. Connectivity effects, on such an approach, are the result of ellipsis. By assimilating VP-fronting to dislocation, the analysis furnishes principled explanations for the striking asymmetries between English-type VP-fronting (dislocation) and German-type VP-fronting ($$\overline A $$-movement).
Claudia Rocha y Claudia Carranza (coords.). Los habitantes del encanto. Seres extraordinarios en comunidades indígenas de América, San Luis Potosí, El Colegio de San Luis / Secretaría de Cultura del Gobierno del Estado de San Luis Potosí, 2015.
Authors: Arranz Conrado J. 
Published: March 2018

Claudia Rocha y Claudia Carranza (coords.). Los habitantes del encanto. Seres extraordinarios en comunidades indígenas de América, San Luis Potosí, El Colegio de San Luis / Secretaría de Cultura del Gobierno del Estado de San Luis Potosí, 2015, 197 pp.
¿Por qué una publicidad ética? Las campañas más polémicas
Authors: Pellicer Jordá María Teresa 
Published: March 2018

La publicidad tiene una gran importancia en la sociedad actual. Determina buena parte de nuestros actos y de nuestra forma de ser. De ahí la importancia de que ésta cumpla con las normas éticas, destacando de entre todas ellas la veracidad. El actual estado de cosas permite que la publicidad sea ejercida sin control por cualquier persona, en cualquier momento y sin garantías para el consumidor. Este, igualmente, se está viendo cada vez más bombardeado por información publicitaria constante y contradictoria, que hace difícil que pueda ejercer un juicio verdaderamente informado y sano con respecto a qué productos compra, como los compra y cuando. En esta situación, los derechos de los consumidores están tan amenazados como la imagen pública de la propia publicidad. Se pierde el respeto a la mentira como arma de convicción y se sacrifican los resultados a largo plazo a favor de tendencias cortoplacistas amparadas en pseudo-filosofías comerciales: se acosa al consumidor con marketing telefónico y digital, ante la falta generalizada de ideas y se buscan soluciones fáciles, en vez de acudir a la verdadera creatividad. En este artículo se ofrecen razones que sustentan estas afirmaciones y que permiten apostar por una verdadera ética publicitaria.
Sensorimotor Representation of Speech Perception. Cross-Decoding of Place of Articulation Features during Selective Attention to Syllables in 7T fMRI
Authors: Archila-Meléndez Mario E. , Valente Giancarlo , Correia Joao M. , Rouhl Rob P. W. , van Kranen-Mastenbroek Vivianne H. , Jansma Bernadette M. 
Published: March 2018

AbstractSensorimotor integration, the translation between acoustic signals and motoric programs, may constitute a crucial mechanism for speech. During speech perception, the acoustic-motoric translations include the recruitment of cortical areas for the representation of speech articulatory features, such as place of articulation. Selective attention can shape the processing and performance of speech perception tasks. Whether and where sensorimotor integration takes place during attentive speech perception remains to be explored. Here, we investigate articulatory feature representations of spoken consonant-vowel (CV) syllables during two distinct tasks. Fourteen healthy humans attended to either the vowel or the consonant within a syllable in separate delayed-match-to-sample tasks. Single-trial fMRI blood oxygenation level-dependent (BOLD) responses from perception periods were analyzed using multivariate pattern classification and a searchlight approach to reveal neural activation patterns sensitive to the processing of place of articulation (i.e., bilabial/labiodental vs. alveolar). To isolate place of articulation representation from acoustic covariation, we applied a cross-decoding (generalization) procedure across distinct features of manner of articulation (i.e., stop, fricative, and nasal). We found evidence for the representation of place of articulation across tasks and in both tasks separately: for attention to vowels, generalization maps included bilateral clusters of superior and posterior temporal, insular, and frontal regions; for attention to consonants, generalization maps encompassed clusters in temporoparietal, insular, and frontal regions within the right hemisphere only. Our results specify the cortical representation of place of articulation features generalized across manner of articulation during attentive syllable perception, thus supporting sensorimotor integration during attentive speech perception and demonstrating the value of generalization.
Lietuvos socialinių verslų novatoriškumas ir darniosios inovacijos: socialinių verslininkių patirtys
Authors: Novelskaitė Aurelija , Pučėtaitė Raminta , Pušinaitė-Gelgotė Rasa 
Published: March 2018

This paper focuses on the perceptions of women social entrepreneurs of in the field of innovativeness forms and sustainable innovations. It presents empirical findings derived from interviews (n=18) with women representatives of social businesses in Lithuania. An analysis of the interview materials reveals that women social entrepreneurs define innovativeness on both individual and organizational levels, but the definition of sustainable innovation was related to moreglobal contexts and technological advancement. The findings correspond to the results of previous works in the field. Thus, on the one hand, the findings denote the universality of the topic; on the other hand, this shows the validity of the Lithuanian study.
Vyras tėvas kaip socialinių paslaugų gavėjas: istorinės patirties raiška socialinio darbuotojo profesinėje komunikacijoje
Authors: Eidukevičiūtė Julija 
Published: March 2018

Each community has social groups that are not affected by the measures of common social policy that help in ensuring family welfare. In those cases, families need an individual social worker’s help in order to integrate into the society, overcome exclusion and poverty. The modern approach to the family as the most important to a child and responsible for his/her social development, and therefore the relationship of the social workers with the family in the process of providing aid should essentially differ from that of the Soviet family welfare system, when the parents had to comply with the norms established by the state, comply with the state-defined ideology. The article aims to discuss how a social worker provides help to a man-father by constructing an interaction with the whole family. The article is built on a qualitative hermeneutical and methodological perspective, which allows us to highlight the importance of social communication and historical experience in the process of family help.
Keywords: fatherhood, social work, hermeneutics
Lyties dimensija socialiniame versle: Lietuvos socialinių verslininkių patirtys
Authors: Novelskaitė Aurelija , Pučėtaitė Raminta , Pušinaitė-Gelgotė Rasa 
Published: March 2018

This paper explores how women – social entrepreneurs – perceive the mission of their social businesses and the effects of gender in the context of such businesses. An analysis of interviews (n=18) with representatives of social businesses in Lithuania reveals that the mission of a social business is either strongly pragmatic (in the organizations that have the legal status of a social enterprise), dissociated from social impact or a rather vague one but that emphasizes goodwill. Meanwhile, the gender dimension in social businesses is approached in rather stereotypical ways: the effect of gender is either ignored or interpreted by stereotypically separating the traditionally female (e.g., caring for and bringing up children) and male (e.g., engineering) fields of activities.