bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic effect of vasoactive intestinal peptide on form-deprived amblyopic kittens
Authors: Li Bo , Zou Yunchun , Li Liwen , Deng Hongwei , Mi Wei , Wang Xing , Yin Ximin 
Published: October 2019

Abstract
Background : Exploring the role of vasoactive intestinal peptide (VIP) in the lateral geniculate body (LGBd) in visual development and studying the therapeutic effect of VIP on amblyopic kittens.
Methods: Three-week-old domestic cats were divided into a control group (n = 10) and a monocular deprivation group (n = 20), with an eye mask covering the right eye of those in the deprived group. After pattern visual evoked potential (PVEP) recording confirmed the formation of monocular amblyopia, the left LGBd was isolated from 5 kittens in each group. The remaining control kittens continued to be raised, and the remaining deprivation group was divided into a VIP intervention group (n = 5), Sefsol (caprylic acid monoglyceride, VIP solution) intervention group (n = 5) and amblyopia non-intervention group (n = 5) after removal of the eye mask. Three weeks later, PVEPs, VIP immunohistochemistry and VIP mRNA expression in the left LGBd were compared across groups.
Results: At 6 weeks of age, there were significant differences in P100 wave latency and amplitude and VIP immunohistochemistry and in situ hybridization between the control group and the deprivation group (P < 0.05). After 3 weeks of the corresponding interventions, the latency and amplitude in the VIP intervention group were better than that in the Sefsol intervention group and amblyopia non-intervention group (P < 0.05). Furthermore, VIP treatment increased the number of immunohistochemical VIP-positive cells (P < 0.05) and the average optical density of positive cells (P > 0.05), as well as the number (P < 0.05) and average optical density of VIP mRNA-positive cells (P < 0.05).
Conclusion s : VIP plays an important role in visual development. Nasal administration of VIP can improve the function of neurons in the LGBd of kittens and has a certain therapeutic effect on amblyopia.
Water-saving irrigation practices for rice yield information and nitrogen use efficiency under sub-tropical monsoon climate
Authors: Huabin Zheng , Wei Zhou , Qimin Chen , Yuanwei Chen , Qiyuan Tang 
Published: October 2019

Abstract
Simple and practical water-saving irrigation practices (WIP) with nitrogen-reduction are beneficial to the development of rice cultivation technology with promotion of resource-conservation and environmental friendliness. The effects of WIP with nitrogen-reduction on population quality, annual yield and nitrogen use efficiency were studied by a field experiment. WIP could maintain or increase the annual yield of rice production models. The highest annual yield of more-water-saving irrigation practice (WIP150) was 8.42 t hm−2 for the double-season rice production model and 12.71 t hm−2 for the ratoon rice production model, respectively. Compared with non-application of nitrogen, the annual yield of nitrogen-reducing practice (NRP) and farms' fertilizer practice (FFP) increased significantly (p &lt; 0.01), while a non-significant difference of annual yield between the FFP and NRP was observed; the annual yield of the NRP and FFP was 9.73 and 10.02 t hm−2 of the double-season rice production model, and 12.84 and 14.34 t hm−2 of the ratoon rice production model, respectively. AEN, PEN, PFPN and RUEN of the NRP were higher than those of the FFP. Therefore, observing the change of water layer in the soil layer via a simple self-made PVC indicator tube, reducing about 20% nitrogen quantity was a feasible and simple cultivation technique for water-saving and nitrogen-reduction in the rice production models.
Targeting Inflammatory Mediators: An Anticancer Mechanism of Thymoquinone Action
Authors: Akter Zakia , Ahmed Faiza Rafa , Tania Mousumi , Khan Md. Asaduzzaman 
Published: October 2019

Background:Thymoquinone is a promising anticancer molecule, the chemopreventive role of which is well-known at least in vitro and in the animal model. In this review article, we focused on the anti-inflammatory activities of thymoquinone in cancer cells.Method:Research data on inflammation, cancer and thymoquinone were acquired from PubMed, Scopus, Web of Science and Google Scholar. We reviewed papers published since the mid of the last century, and the most cited papers of the last ten years.Results:Studies indicate that thymoquinone possesses immunomodulatory activities, in addition to its chemopreventive role, as thymoquinone can target and modulate inflammatory molecules, like nuclear factor kappa B (NF-κβ), interleukins, tumor necrosis factor-α (TNF-α), and certain growth factors. As chronic inflammation plays an important role in cancer development, controlling inflammatory pathways is an important mechanism of an anticancer molecule, and modulation of inflammatory pathways might be one of the key mechanisms of thymoquinone’s anticancer activities.Conclusion:This article reviewed the role of inflammation on cancer development, and the action of thymoquinone on inflammatory molecules, which have been proved in vitro and in vivo. Much attention is required for studying the role of thymoquinone in immunotherapeutics and developing this molecule as a future anticancer drug.
In vitro Gastrointestinal Models for Prebiotic Carbohydrates: A Critical Review
Authors: Hernandez-Hernandez Oswaldo 
Published: October 2019

Background:
In the last decade, various consortia and companies have created standardized digestion
protocols and gastrointestinal simulators, such as the protocol proposed by the INFOGEST Consortium, the simulator
SHIME, the simulator simgi®, the TIM, etc. Most of them claim to simulate the entire human gastrointestinal
tract. However, few results have been reported on the use of these systems with potential prebiotic carbohydrates.

Methods:
This critical review addresses the existing data on the analysis of prebiotic carbohydrates by different in
vitro gastrointestinal simulators, the lack of parameters that could affect the results, and recommendations for
their enhancement.

Results:
According to the reviewed data, there is a lack of a realistic approximation of the small intestinal conditions,
mainly because of the absence of hydrolytic conditions, such as the presence of small intestinal brush border
carbohydrases that can affect the digestibility of different carbohydrates, including prebiotics.

Conclusion:
There is a necessity to standardize and enhance the small intestine simulators to study the in vitro
digestibility of carbohydrates.
El rol del contador público en México ante la nueva contabilidad electrónica
Authors: Castañeda Barrera María del Consuelo , Pérez Paredes Alfredo , Velasquez de la Rosa Ylda Celia , Candía Díaz María del Rosario 
Published: October 2019

Ante las constantes y determinantes reformas fiscales, hoy por hoy, es responsabilidad social del Contador Público analizar e informar al empresario el verdadero impacto financiero de la contabilidad electrónica, en virtud de que el fisco, a fin de lograr mayor eficiencia en sus procedimientos de comprobación y garantizar la veracidad del pago de impuestos de los contribuyentes cautivos, determinado anteriormente de forma libre por el contador público, actualmente la autoridad fiscal en México, ha impuesto nuevas bases eliminando ahora más que nunca gastos, inversiones y costos que a su juicio, sean ajenos a la actividad normal de la empresa, ha reformado regímenes tributarios, nuevas formas de facturación electrónica, y algunas otras disposiciones que afectan al contribuyente cautivo considerablemente en el aspecto financiero.
El objetivo es comentar aspectos financieros relevantes que impactan en la empresa con la obligación de llevar la contabilidad de manera electrónica y la importancia de esta en la toma de decisiones de negocios. Debido a la importancia que reviste la contabilidad electrónica, resulta imprescindible presupuestar operaciones de compras, ventas, gastos y utilidades, además de revisar y validad todos los documentos digitales observando requisitos fiscales y contar con los archivos respectivos, así como documentar las operaciones, expidiendo y recabando los comprobante fiscales digitales de las transacciones económicas de compra, venta, gastos y nominas en formatos XML.
Percepción de microempresarios poblanos ante el funcionamiento del Instituto Nacional del Emprendedor como política pública
Authors: Pérez Paredes Alfredo , Cruz de los Ángeles José Aurelio , Torralba Flores Amado 
Published: October 2019

El fenómeno emprendedor ha tomado mayor importancia en los últimos años y es por ello muy importante que los diferentes órdenes de gobierno de cualquier nación, asuma una postura responsable ante este hecho, sobre todo, cuando se identifican cuáles son las principales características y motivaciones que tienen los emprendedores para iniciar una empresa, lo que permite tener una radiografía de cuáles son los requerimientos para que las personas decidan emprender y las que ya lo lograron puedan mantenerse y poder crecer y es por ello que las políticas públicas implementadas para tal fin, cobran una mayor importancia, sobre todo en aquellos países que se encuentran en vías de desarrollo como lo es México. Lo anterior, permite reflexionar la relevancia que tiene el que los emprendedores que han identificado una buena idea de inversión y los empresarios ya establecidos requieren de un apoyo por lo regular de tipo financiero, que les permita generar condiciones de competitividad y adaptación a los nuevos entornos económicos y sociales, que provocan que los empresarios tengan que ser más innovadores y creativos. Por ello el presente trabajo de investigación busca analizar cómo perciben los empresarios sobre todos los de tamaño micro y pequeño en el municipio de Puebla en México, una de las políticas públicas implementadas por el actual Gobierno Federal denominado Instituto Nacional del Emprendedor (INADEM), considerando que dos de los objetivos establecidos por este Instituto son: a) Promover un entorno jurídico y reglamentario propicio para el desarrollo de Emprendedores y MIPYMES
The Effect of Performance Reporting Frequency on Employee Performance
Authors: Hecht Gary , Hobson Jessen L. , Wang Laura W. 
Published: October 2019

ABSTRACT
Conventional wisdom suggests that frequent performance reporting is beneficial for decision making, as it can enhance timeliness and usefulness of the reported information for decision making. We investigate a potential motivational cost of frequent performance reporting. Using goal orientation theory, we predict and find that frequent performance reporting has negative motivational and performance implications when employees know or assume that the information they report will be used to evaluate their task-related skill. Our theory and results suggest that organizations need to balance the informational benefits and motivational costs of frequent reporting when designing their performance reporting systems. In addition, our theory and results can help organizations begin to design solutions that take advantage of the informational advantage of frequent reporting while minimizing its motivational costs.
Contos tradicionais e as crianças: diálogos entre Portugal e Brasil
Authors: Brandão Claudia Leite , Balça Ângela 
Published: October 2019

O conto tradicional é marcado por características da narratividade e, por nascer da oralidade, é considerado um gênero importante que proporciona a leitores e ouvintes a inserção no mundo da literatura. Ademais, integra a cultura e o imaginário das pessoas, acompanhando-as ao longo do tempo. Pretende-se atribuir visibilidade ao gênero, com o objetivo de refletir acerca desse patrimônio cultural, por meio de análise do conto Caldo de pedra, na versão portuguesa, recolhida por Teófilo Braga, no século 19, e ainda na releitura em português de Portugal, escrita por Alice Vieira (2018) e ilustrada por Vanda Romão. Lançar-se-ão olhares, também, sobre a versão em português do Brasil, escrita por Ana Maria Machado (2004) e ilustrada por Odilon Moraes. Desse modo, importa reiterar que, para a seleção do conto, considera-se como mote Teófilo Braga, em sua obra Contos tradicionais do povo português. O procedimento metodológico baseia-se na revisão de literatura, com obras que versam sobre o tema referido. Norteia-se a construção deste artigo com base na concepção de que esse gênero atua, significativamente, na formação e ampliação do repertório da criança, seja leitora ou ouvinte.
PAPR Reduction and Data Security Improvement for OFDM Technique Using Chaos System
Authors: Abdullah Muntadher Kadhim , Ibada Ali Jawad 
Published: October 2019

Orthogonal Frequency Division Multiplexing (OFDM) is the most popular multicarrier technique because it produces several advantages such as higher spectral efficiency, high transmission rate, robustness to fading channel and etc.. In this technique, the data is carrying by multiple orthogonal subcarriers. If all subcarriers are adding together with the same phase, it will result high Peak to Average Power Ratio (PAPR). Higher value of PAPR makes low power efficiency, several degradation of performance in the transmit power amplifier and increase the complexity of converters. It is important to decrease PAPR for avoid these problems. Another requirement of the modern communication system is the security of transmission data. All these issues make strong motivation for building algorithm to improve performance and security of OFDM system. In this paper, a proposed algorithm is presented to both reduce PAPR and secure the OFDM signal by generating several Aperiodic PseudoRandom Binary Sequences (APRBSs) using chaos system. The proposed algorithm is scrambling the information by APRBSs, and one sequence is chosen for transmission which has smallest PAPR value. To inform receiver which sequence had been sent, a Side Information (SI) is enclosed with the transmitted sequence. Because SI very important at receiver, convolutional code with Viterbi-Soft Decision Decoding (V-SDD) is used to protect it against channel distortion. Simulation results state the proposed algorithm produces excellent PAPR reduction performance and approximately gives the same Bit Error Rate (BER) of the conventional OFDM system over AWGN and fading channels. In addition to get better performance, the proposed algorithm is providing a good data security due to chaos system. MATLAB program is used to build the proposed OFDM system and get the simulation results.
HUBUNGAN PENGETAHUAN KELUARGA DENGAN PERILAKU PEMBATASAN CAIRAN PADA PASIEN GAGAL GINJAL KRONIK
Authors: Saputra Edi , Isroin Laily , Mas’udah Anni Fitriyatul 
Published: October 2019

Salah satu perawatan pada GGK adalah pembatasan cairan. Kurangnya pengetahuan keluarga terhadap pembatasan cairan pada anggota keluarga yang menderita penyakit GGK akan menyebabkan perilaku yang salah dalam membatasi jumlah cairan yang akan menimbulkan komplikasi. Perilaku keluarga dirumah dalam pembatasan cairan pada pasien GGK akan mempertahankan keseimbangan cairan. Tujuan penelitian ini adalah untuk mengetahui Hubungan Pengetahuan Keluarga Dengan Perilaku Pembatasan Cairan Pada Pasien Gagal Ginjal Kronik di RSUD Dr.Harjono Ponorogo.Penelitian ini mengunakan desain penelitian kuantitatif dengan study korelasi, rancangan penelitian yang digunakan cross sectional, dengan populasi seluruh keluarga responden dengan GGK di ruang Hemodialisa RSUD Dr.Harjono Ponorogo sejumlah 2.603 dan sampel 53 responden yang diperoleh melalui teknik purposive sampling, pengumpulan data menggunakan kuesioner selanjutnya dilakukan pengolahan data melalui tahap Editing, Coding, Tabulating,analisa data mengunakan uji statistik Chi-Square dengan softwere IBM SPSS Statisticversion 16.0. Berdasarkan hasil penelitian ini menunjukkan bahwa dari 53 responden adalah berpengetahuan baik dengan perilaku positif yaitu 72,4% sedangkan pengetahuan baik dengan perilaku negatif yaitu 20,8% , dan pengetahuan buruk dengan perilaku positif yaitu 27,6%, sedangkan pengetahuan buruk dengan perilaku negatif yaitu 9,6%. Analisa data statistik menunjukan nilai signifikan p= 0,00 <α (0,05) terdapat hubungan pengetahuan keluarga dengan perilaku pembatasan cairan pada pasien gagal ginjal kronik di ruang Hemodialisa RSUD Dr.Harjono Ponorogo.Berdasarkan penelitian ini dapat disimpulkan bahwa semakin baik pengetahuan keluarga dalam pembatasan cairan maka semakin rendah perilaku negatif dan jika pengetahuan keluarga rendah dalam pembatasan cairan maka semakin tinggi perilaku negatif.
The agricultural impact of the 2015–2016 floods in Ireland as mapped through Sentinel 1 satellite imagery
Authors: O’Hara R. , Green S. , McCarthy T. 
Published: October 2019

AbstractThe capability of Sentinel 1 C-band (5 cm wavelength) synthetic aperture radio detection and ranging (RADAR) (abbreviated as SAR) for flood mapping is demonstrated, and this approach is used to map the extent of the extensive floods that occurred throughout the Republic of Ireland in the winter of 2015–2016. Thirty-three Sentinel 1 images were used to map the area and duration of floods over a 6-mo period from November 2015 to April 2016. Flood maps for 11 separate dates charted the development and persistence of floods nationally. The maximum flood extent during this period was estimated to be ~24,356 ha. The depth of rainfall influenced the magnitude of flood in the preceding 5 d and over more extended periods to a lesser degree. Reduced photosynthetic activity on farms affected by flooding was observed in Landsat 8 vegetation index difference images compared to the previous spring. The accuracy of the flood map was assessed against reports of flooding from affected farms, as well as other satellite-derived maps from Copernicus Emergency Management Service and Sentinel 2. Monte Carlo simulated elevation data (20 m resolution, 2.5 m root mean square error [RMSE]) were used to estimate the flood’s depth and volume. Although the modelled flood height showed a strong correlation with the measured river heights, differences of several metres were observed. Future mapping strategies are discussed, which include high–temporal-resolution soil moisture data, as part of an integrated multisensor approach to flood response over a range of spatial scales.
Elevated lactic acid during ketoacidosis: pathophysiology and management
Authors: Ahmed Hamda Houssein , De Bels David , Attou Rachid , Honore Patrick M. , Redant Sebastien 
Published: October 2019

Abstract
Lactic acidosis results from an acid-base balance disorder of the body due to an excess of lactic acid. It is frequently found in critically ill patients admitted to the intensive care. The most common cause is type A, found in pathologies such as cardiogenic, septic and hypovolemic shock, trauma and severe hypoxemia. The type B is less common and arises without evidence of tissue hypoperfusion or shock. Divers etiologies have been described for this type of hyperlactatemia: Grand Mal seizures, liver failure, hematologic malignancies, congenital enzyme deficiencies, thiamine deficiencies and diabetes mellitus and also alcohol abuse, which may induce a lactic acid under-use or an increased production. The authors describe a rare complication of type 1 Diabetes Mellitus (T1DM), leading to a major and persistent expression of a type B lactic acidosis during ketoacidosis.
Issue Salience on Twitter During Swedish Party Leaders’ Debates
Authors: Sandberg Linn A.C. , Bjereld Ulf , Bunyik Karina , Forsberg Markus , Johansson Richard 
Published: October 2019

Abstract
The objective of this study is to contribute knowledge about formation of political agendas on Twitter during mediated political events, using the party leaders’ debates in Sweden before the general election of 2014 as a case study. Our findings show that issues brought up during the debates were largely mirrored on Twitter, with one striking discrepancy. Contrary to our expectations, issues on the left-right policy dimension were more salient on Twitter than in the debates, whereas issues such as the environment, immigration and refugees, all tied to a liberal-authoritarian value axis, were less salient on Twitter.
Hypersensitivity pneumonitis in a teenager
Authors: Salmen Teodor , Strâmbu Irina 
Published: October 2019

Abstract
Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD), consequence of an alveolar allergic reaction against various inhaled allergens occurring in susceptible individuals, manifesting as an acute or chronic granulomatous alveolar allergic process against inflammation of the lung parenchyma. The clinical presentation can mimic acute respiratory infections (in acute form) or an idiopathic ILD (in chronic form); the diagnosis of HP is difficult if the exposure to allergen is not suspected.
We present the case of a male teenager, pigeon breeder, presenting with recurrent episodes of dyspnoea and fever, initially considered and treated as pneumonia. The diagnosis of HP was based on suggestive imaging changes, lymphocytic alveolitis at bronchoalveolar lavage with a low CD4/CD8 ratio and a thorough anamnesis for exposure and positive IgG serum precipitins against pigeon debris. The patient improved over a few months only by avoiding exposure to the incriminated allergen. ILDs in children and adolescents are considered rare diseases, with HP being one of the possible causes in older children and adolescents.
Inflammatory myofibroblastic tumours of the lung: a case series
Authors: Melinte Alexandru , Strâmbu Irina , Leonte Diana , Dumitrescu Mihai , Paleru Cristian , Bolca Ciprian 
Published: October 2019

Abstract
Inflammatory myofibroblastic tumours represent a rare group of lesions reported in various organs but with an unclear aetiology. Although so far they are considered benign, some cases of recurrence and invasive behaviour have been noted. We report three consecutive cases of tumours of the lung, with heterogeneous clinical presentation. They were all treated by means of surgery, with good long-term results. Diagnosing an inflammatory myofibroblastic tumour relies mainly on an experienced pathologist.
Sleep apnea syndrome and heart failure—mechanisms and consequences
Authors: Loredana Ardelean Carmen , Florin Lighezan Daniel , Pescariu Sorin , Nadasan Valentin , Pleava Roxana , Mihaicuta Stefan 
Published: October 2019

Abstract
Heart failure (HF) remains a major public health issue despite advances in treatment, being associated with increased morbidity and mortality, multiple hospitalization and, implicitly, very high economic costs. Therefore, it becomes increasingly important to identify and treat factors or comorbidities that contribute to the progression of HF. Breathing disorders during sleep (sleep-disordered breathing), especially sleep apnea syndrome, obstructive or central form, may be one of these factors.
The Problem of Designating Elementary Terrains for the Purpose of Szczecin Algorithm of Real Estate Mass Appraisal
Authors: Hozer Józef , Gnat Sebastian , Kokot Sebastian , Kuźmiński Wojciech 
Published: October 2019

Abstract
One of the key determinants of the quality of real estate mass appraisal is the algorithm used for conducting such an appraisal. Other determinants include detailed methodological and substantive solutions within the scope of a selected, applied algorithm. This article is dedicated to one of the major stages of the process of land real estate mass appraisal with the use of the Szczecin Algorithm of Real Estate Mass Appraisal (SAREMA), namely defining and determining the so-called elementary terrains. The paper aims to present the methods for designating the boundaries of elementary terrains, the manner of defining their number and size and, consequently, the number of real properties that will be covered by an automated process of mass appraisal in a given area.
Ways of defining the boundaries of elementary terrains were proposed in the paper based on the existing surveying districts, zoning plans, background maps, thematic map layers, real estate market analyses as well as statistical methods.
Elementary terrain boundaries thus designated were verified with the use of actual real estate resources of the city of Szczecin.