bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lost in Translation: Video Games Becoming Cultural Heritage?
Authors: Eklund Lina , Sjöblom Björn , Prax Patrick 
Published: June 2019

Recent attention to the question of preservation and exhibition of video games in cultural institutions such as museums indicates that this media form is moving from being seen as contentious consumer object to cultural heritage. This empirical study examines two recent museum exhibitions of digital games: GameOn 2.0 at the National Museum of Science and Technology in Stockholm (TM), and Women in Game Development at the Museum of Art and Digital Entertainment, Oakland (MADE). The aim is to explore how games are appropriated within such institutions, and thereby how they are configured as cultural heritage and exhibitable culture. The study uses actor-network theory in order to analyse heterogeneous actors working in conjunction in such processes, specifically focusing on translation of games and game culture as they are repositioned within museums. The study explores how games are selectively recruited at both institutions and thereby translated in order to fit exhibition networks, in both cases leading to a glossing over of contentious issues in games and game culture. In turn, this has led to a more palatable but less nuanced transformation of video games into cultural heritage. While translating video games into cultural heritage, the process of making games exhibitable lost track of games as culture by focusing on physical artefacts and interactive, playable fun. It also lost track of them as situated in our culture by skimming over or ignoring the current contentious nature of digital games, and finally, it lost track of games as being produced and experienced in a particular context, or games of culture.
Two-grid full-waveform Rayleigh-wave inversion via a genetic algorithm — Part 2: Application to two actual data sets
Authors: Xing Zhen , Mazzotti Alfredo 
Published: June 2019

We have applied our two-grid genetic-algorithm Rayleigh-wave full-waveform inversion (FWI) to two actual data sets acquired in Luni (Italy) and Grenoble (France), respectively. Because our technique used 2D elastic finite-difference modeling for solving the forward problem, the observed data were 3D to 2D corrected prior to the inversion. To limit the computing time, both inversions focused on predicting low-resolution, smooth models by using quite coarse inversion grids. The wavelets for FWI were estimated directly from the observed data by using the Wiener method. In the Luni case, due to the strong dispersion effects on the data, to strengthen the inversion, envelopes and waveforms were considered in the objective function and an offset-marching strategy was applied. Though no a priori information was exploited, the outcomes of the Luni and Grenoble data inversion were fair. The predicted Luni [Formula: see text] model indicates a strong velocity increase from approximately 3 to 6 m, and velocity inversions have been detected at approximately 2 and 9 m depths. Analyzing the dispersion spectra, it results that the predicted Luni data reasonably reproduced the waveforms related to the fundamental mode and, likely, a small part of those related to the first higher mode. Concerning the Grenoble example, the predicted [Formula: see text] model coincides reasonably well with the long-wavelength structures presented in the [Formula: see text] profiles obtained from nearby boreholes. The data reconstruction is generally satisfactory, and when mismatches occur between the predicted and observed traces, the phase differences are always within half-periods. The fair inversion outcomes suggest that the predicted Luni and Grenoble models would likely be adequate initial models for local FWI, which could further increase the resolution and the details of the estimated [Formula: see text] models.
Diagnostic Challenge in PLIN1-Associated Familial Partial Lipodystrophy
Authors: Jéru Isabelle , Vantyghem Marie-Christine , Bismuth Elise , Cervera Pascale , Barraud Sara ,   PLIN1-Study Group, Auclair Martine , Vatier Camille , Lascols Olivier , Savage David B , Vigouroux Corinne 
Published: June 2019

Abstract

Context
Heterozygous frameshift variants in PLIN1 encoding perilipin-1, a key protein for lipid droplet formation and triglyceride metabolism, have been implicated in familial partial lipodystrophy type 4 (FPLD4), a rare entity with only six families reported worldwide. The pathogenicity of other PLIN1 null variants identified in patients with diabetes and/or hyperinsulinemia was recently questioned because of the absence of lipodystrophy in these individuals and the elevated frequency of PLIN1 null variants in the general population.

Objectives
To reevaluate the pathogenicity of PLIN1 frameshift variants owing to new data obtained in the largest series of patients with FPLD4.

Methods
We performed histological and molecular studies for patients referred to our French National Reference Center for Rare Diseases of Insulin Secretion and Insulin Sensitivity for lipodystrophy and/or insulin resistance and carrying PLIN1 frameshift variants.

Results
We identified two heterozygous PLIN1 frameshift variants segregating with the phenotype in nine patients from four unrelated families. The FPLD4 stereotypical signs included postpubertal partial lipoatrophy of variable severity, muscular hypertrophy, acromegaloid features, polycystic ovary syndrome and/or hirsutism, metabolic complications (e.g., hypertriglyceridemia, liver steatosis, insulin resistance, diabetes), and disorganized subcutaneous fat lobules with fibrosis and macrophage infiltration.

Conclusions
These data suggest that some FPLD4-associated PLIN1 variants are deleterious. Thus, the evidence for the pathogenicity of each variant ought to be carefully considered before genetic counseling, especially given the importance of an early diagnosis for optimal disease management. Thus, we recommend detailed familial investigation, adipose tissue-focused examination, and follow-up of metabolic evolution.
Outcome of complex non-unions of femoral fractures managed with Ilizarov method of distraction osteogenesis
Authors: Bakhsh Karim , Zimri Faridullah Khan , Rehman Atiq -Ur- , Mohammad Eid , Saaiq Muhammad 
Published: June 2019

Objective: To evaluate the management outcome of complex non-union of femoral fractures with Ilizarov method in terms of bone union, functional results and any complications.
Methods: This case series study was carried out at the Departments of Orthopedic Surgery, National Institute of Rehabilitation Medicine (NIRM), Islamabad and Civil hospital, Quetta over a period of three and half years, January 1, 2015 to June 30,2018.
Results: There were 50 patients in the study. There were 48(96%) males and 2(4%) females. The ages ranged between 17-54 years with a mean of 33.58±8.9 years. As per ASAMI criteria, the bone results were excellent in 17(34%), good in 30(60%), fair in 1(2%) and poor in 2(4%) patients. The functional results were excellent in 15(30%), good in 24(48%), fair in 8(16%) and poor in 3(6%). The bone union rate was 98% whereas infection eradication rate was 94%. The most frequent complications were pin tract infection affecting 80% patients, knee stiffness 60% patients and K-wires loosening 20% patients.
Conclusion: The Ilizarov method provides an effective solution to address the complex non-union of femur fractures. It helps to ensure fracture healing, eradicates infection and provides good functional outcome. The attended complications are mild to moderate and manageable with conservative means.
doi: https://doi.org/10.12669/pjms.35.4.244
How to cite this:Bakhsh K, Zimri FK, Atiq-Ur-Rehman, Mohammad E, Saaiq M. Outcome of complex non-unions of femoral fractures managed with Ilizarov method of distraction osteogenesis. Pak J Med Sci. 2019;35(4):1055-1059. doi: https://doi.org/10.12669/pjms.35.4.244
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Methylglyoxal: Antimicrobial activity against blood culture isolates of Salmonella Typhi and other Gram negative rods
Authors: Afzal Raja Kamran , Khalid Fizza , Hannan Abdul , Ahmed Syed Azhar 
Published: June 2019

Objectives: To evaluate the activity of Methylglyoxal against the blood culture isolates of Salmonella Typhi and various Gram negative rods and to compare the activity of Methylglyoxal against S. Typhi and other Gram negative rods.
Methods: It was an experimental study conducted at the Department of Microbiology, University of Health Sciences (UHS), Lahore-Pakistan in collaboration with the Department of Microbiology, CMH Lahore, from July 2011 to June 2012. Recent blood culture isolates of S. Typhi and other Gram negative rods were collected from different hospitals of Lahore and kept stored at -80°C. As per the latest CLSI guidelines, morphological, biochemical and serological identification was carried out and antimicrobial susceptibility was tested. A multi-point inoculator was used to carry out agar dilution for determination of MICs of MGO. Results were determined after compilation of data using latest SPSS version.
Results: MIC90 of MGO against the clinical isolates of S. Typhi was 0.20 mg/mL (2.8 mM) and against Gram negative rods it was 0.21 mg/mL (3.0 mM). The p-value of MICs of MGO against the isolates of S. Typhi was 0.023 when compared with Gram negative rods (p<0.05; statistically significant).
Conclusion: MGO has a scientifically proven in vitro antimicrobial activity against blood culture isolates of S. Typhi and various Gram negative rods.
doi: https://doi.org/10.12669/pjms.35.4.807
How to cite this:Afzal RK, Khalid F, Hannan A, Ahmed SA. Methylglyoxal: Antimicrobial activity against blood culture isolates of Salmonella Typhi and other Gram negative rods. Pak J Med Sci. 2019;35(4):1110-1114. doi: https://doi.org/10.12669/pjms.35.4.807
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Redefining Consumer Utility in the Perspective of Islamic Economics Framework
Authors: Muttaqin Zein , Pusparini Martini Dwi 
Published: June 2019

An interest of individual preferences which can be represented in numerical ways known as the utility. While others stated it as a matter of subjective feeling that being felt in order to pursue and to maximize the certain level of satisfaction and personal well-being. According to neoclassical theory, this happened due to the contraction consumer preferences between things/products/services that available in the market. Furthermore, the ultimate ends that have been proposed are that the industry/market is spiritually neutral. On the other hand, some of Muslim scholars argue that spiritual or religious values are what defines an individual as a human, while all conducted of consumption is abide by ethics and religious values, which will not forsake others for personal gains. The integration of religious aspect in pursuing of maximization of utility is known as maslahah (i.e. well-being). A further discussion that arises is in Islamic economics framework, does individual orients solely to maximize their utility, even in the sense of maslahah is considered. Neoclassical claims that to interpret the utility, there are two headings is considered, they are prediction approach and prescription approach. The debate on neoclassical and Islamic economics perspectives might contradict one to another, but none of it is at absolute truth, the theory itself is still developing due to different assumptions and circumstances that present at that time. Furthermore, the revisiting theory of maqasidh al-sharia (i.e. the objective of Islamic Laws) also provides a different point of view regarding the debatable utility between neoclassical and Islamic economics. In pursuance of better understanding of utility, this article aims to redefine the consumer utility in Islamic economics framework. It can be concluded that the definition of utility under Islamic perspective as the act to seek self-actualization of benefit which collide to the benefit of others in pursuing of enhancement of dual dimensions objectives of present and hereafter. A strong point that being found that in order to maximize the utility/maslahah must consider the possibility of misleading the genuine motive of utility, which is not adjusting it under social pressures. The misleading act of such is categorized as the act of falsification of preferences.
A QUESTÃO JUDAICA: A TRANSIÇÃO DO JOVEM MARX DA CRÍTICA FILOSÓFICA À CRÍTICA DA ECONOMIA POLÍTICA
Authors: Fresu Gianni 
Published: June 2019

O escrito sobre a questão judaica é de fundamental importância para entender aformação intelectual do jovem Marx, no percurso que o levou da crítica filosófica à crítica da economia política. Nesse trabalho, ele levanta a necessidade de superar a formulação teológica da questão judaica para chegar ao coração da contradição que determina a alienação do homem na sociedade moderna. A capacidade de emancipação do judeu reside na relação do judaísmo com a emancipação do mundo de hoje, não com a simples emancipação do Estado da religião. Na Questão judaica, escrita no outono de 1843 e publicada nos “Anais franco-alemães” de fevereiro de 1844, Marx polemiza com Bauer, afirmando que a completa emancipação do homem não pode limitar-se apenas à emancipação política, mas precisaria atingir as relações sociais e produtivas. O mesmo acontece na Introdução à Crítica da filosofia do direito, também escrita para os Anais franco-alemãs no final de 1843 e publicado em fevereiro de 1844, ondeencontramos o definitivo abandono da simples crítica religioso-política e o encaminhar-se da crítica social marxiana. Na Questão judaica e na Introdução, Marx se emancipa completamente da influência de Bauer, portanto, na passagem de 1843 para o 1844, estas três etapas representam momentos essenciais na formação da visão filosófica do jovem Marx.
SOBRE A RECEPÇÃO DAS OBRAS DE MARX E ENGELS ATÉ 1989
Authors: Costa Neto Pedro Leão da 
Published: June 2019

O objetivo do presente artigo e, por um lado, analisar a história da constituição docorpus das obras de Karl Marx e Friedrich Engels e das sucessivas tentativas de publicação das suas Obras Completas (MEGA, MEW, MEGA2), procurando identificar os vários obstáculos de natureza política e teórica que retardaram a sua realização. Por outro lado, procura-se, igualmente, evidenciar a relação deste processo com a história da difusão e recepção das obras de Marx e Engels.
The Electromagnetic Field in the Vicinity of Radio-Navigation Systems
Authors: Jóźwik-Michałowska Natalia , Felski Andrzej 
Published: June 2019

AbstractToday, electromagnetic waves are the basic medium for all communication tasks. This applies also to navigation, where the most commonly waves have lengths measured in centimetres (radar, GPS) and longer, such as the waves used in the AIS or DGPS technologies. Navigators are mostly interested in the communication functionality of the used systems, i.e. such factors as range of the system and signal-to-noise ratio. This leads directly to increasing the transmitters’ power. However, it is important to bear in mind that the electromagnetic field can endanger human health, therefore, establishing the level of radiation both on vessels and near the shore transmitters is crucial in this context. The experience of authors shows that the knowledge of the most of navigators hereupon is not large. From this result extremely irresponsible behaviors of one persons, as well as inexplicable phobias others.This article presents the subject using the example of the electromagnetic field present near a lighthouse emitting AIS and DGPS signals. Relevant measurements were made at the Rozewie lighthouse by certified laboratory of Maritime Institute in Gdansk according the polish standards and internal, certified procedures. Results of the measurements were related to the national and European standards for electromagnetic field measurements in the context of occupational health and safety.
Detection of Small Bottom Objects From Multibeam Echosounder Data
Authors: Iwen Dominik , Wąż Mariusz 
Published: June 2019

AbstractMultibeam Echo Sounder Systems (MBES) shallow water surveys provide capability not only acquiring bathymetric data useful for determining isobaths and mapping features on the seafloor which may be a hazard to navigation. They also allow detection of objects smaller or deeper than those required for the safety of seafaring and International Hydrography Organization (IHO) standards. In this article some of issues related to of efficient MBES shallow water surveys are stressed. Additionally a draft of post-processing techniques and result data format together with tools allowing extraction of bottom object from bathymetric data are presented.
The Use of Automatic Communication System on Example of a Conversation Between M/V Corcus J and M/V Baltic Ace
Authors: Wójcik Anna , Banaś Paweł 
Published: June 2019

AbstractArticle presents the applications designed to perform automatic communication as a support for navigators steering their ships. Authors took into consideration the conversation between navigators in the collision situation that occurred at North Sea basin. The performed incorrect communication has been presented and alternative to it has been proposed. The results of simulation made with use of the prototype of automatic communication and negotiation system has been shown.
Hybrid Optical Amplifier for Flat Gain in Super Dense Wavelength Division Multiplexed (SDWDM) System
Authors: Wason Amit , Malik Deepak 
Published: June 2019

Abstract
Large capacity optical networks require flattened gain spectrum and large gain bandwidth of the optical networks. In order to achieve this large number of hybrid optical amplifiers are designed. Here we proposed a competent flat gain hybrid optical amplifier with an optimum combination of Erbium Doped Fiber Amplifier (EDFA) and Raman amplifier. Attempts are made to design a hybrid optical amplifier for 100 channels, 10 Gbps Super Dense Wavelength Division Multiplexed (SDWDM) systems at different channel spacing of 0.1, 0.2, 0.4 and 0.8 nm. Work capacity of the network was compared on the basis of various parameters viz., gain and noise figure that determined the performance of the system. The gain spectrum of the hybrid optical amplifier depends upon the parameters viz., pump wavelength, pump power and laser input power of the amplifier. Various efforts were conceded out to optimize these parameters. It was found that for wavelength range 1,570.5–1,580.75 nm, a flat gain of 5.36 dB is achieved for input power of −15 dB with noise figure variation of 0.57 dB without using any gain flattering scheme. Being simple and cost effective, this hybrid optical amplifier could be recommended for gain flatness characteristics and acceptable noise figure for super dense wavelength division multiplexed system.
Dosimetric characteristics and applications of cross-linking and degradation of a natural biopolymer Gum Acacia
Authors: Gafar Sameh M. , Abdel-Kader Nehad M. 
Published: June 2019

Abstract
The current study covers the effect of gamma rays on a natural biopolymer Gum Arabic (GA). Gum acacia has a very wide range applications in various fields, that a comparison between two dosimetry systems; the first system depends on the radiolysis of GA (mixing poly-vinyl alcohol) as a thin-film dosimeter. The second system depends on the same material GA as solutions dosimeter, which is more sensitive to γ-radiation due to free mobility of free radicals released by the action of gamma rays. The prepared GA/film/solutions have a considerable peak at 289 nm, which increases (cross-linking of GA polymer) upon irradiation until 28 and 6 kGy for two systems, respectively in case of the first step. However, upon increased the absorbed doses and the intensity of the signal decrease with increasing radiation dose (degradation of GA polymer) up to 80 and 15 kGy for film and solutions. Radiation chemical yield G-(value); dose-response function; gamma radiation sensitivity; also pre- and post-irradiation stability under various conditions were illustrated.
Crocin (active constituent of saffron) improves CCl4-induced liver damage by modulating oxidative stress in rats
Authors: Cosgun Binnaz Elif , Erdemli Mehmet Erman , Gul Mehmet , Gul Semir , Bag Harika Gozukara , Erdemli Zeynep , Altinoz Eyup 
Published: June 2019

Abstract

Background
CCl4 is a widely used xenobiotic for the purpose of causing liver damage in experimental studies. In this study, we aimed to reveal the effects of crocin on liver injury caused by CCl4 via free radical scavenging properties.

Materials and methods
Animals were divided into five groups of 10: control; corn oil; crocin; CCl4; CCl4 + crocin. Tissue samples were carefully removed and separated for biochemical and histological investigations.

Results
CCl4 administration led to significant increases in MDA, SOD, CAT and TOS in liver tissue, and AST, ALT and ALP levels in plasma (p < 0.05). In addition, CCl4 caused significant decreases in GSH and TAS (p < 0.05). When animals were treated with crocin, high MDA, SOD, CAT, TOS levels, and AST and ALP activities decreased and GSH and TAS levels increased. Control group exhibited normal histological appearance; however extensive necrosis areas were detected in the CCl4 group. In the CCl4 + crocin group, pathological changes were markedly decreased and the appearance of liver tissue was almost similar to the control groups.

Conclusion
Our results showed that crocin suppresses oxidative stress with antioxidant properties and has a protective effect on tissue damage caused by CCl4.
Potential of CZTSe Solar Cells Fabricated by an Alloy-Based Processing Strategy
Authors: Taskesen Teoman , Pareek Devendra , Nowak David , Kogler Willi , Schnabel Thomas , Ahlswede Erik , Gütay Levent 
Published: June 2019

Abstract
In this manuscript, we give an overview of the main insights into our growth procedure for kesterite solar cells and show the possibilities that are provided by this approach. The importance of using Cu–Sn alloy instead of elemental Sn and Cu in the precursor is shown. We discuss how the alloy approach stabilises the composition and helps guide the process along a preferred reaction pathway. A summary of our previously reported findings in the context of our latest results on kesterite solar cells prepared from Cu–Sn alloyed precursors is drawn. The positive impact of an alloy precursor configuration on the formation pathway, process control, and process resilience is demonstrated. Furthermore, a new optimisation strategy for kesterite, based on the reported pathway, is discussed, including a smooth phase transition from Cu-rich to Cu-poor kesterite. Finally, we demonstrate results on buffer optimisation and the application of a promising hybrid buffer configuration of CdS/Zn(O,S), which can reduce the optical losses in the solar cell structure.