bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analyzing the behavior of bicyclists using a bicycle simulator with a coupled SUMO and DYNA4 simulated environment
Authors: Kaths Heather , Keler Andreas , Kaths Jakob , Busch Fritz 
Published: August 2019

Operational behavior models are used in traffic simulations to represent the subconscious, short-termdecisions made by road users to respond to other road users, the infrastructure and traffic control measures. Calibration and validation of these models can be achieved using observed trajectory data from real road users. For lane bound traffic, it is assumed that road users intend to follow a given lane with a certain desired speed across the intersection. Any deviation from this planned path is in response to other road users or the environment. It is difficult, however, to identify and separate the desired movement of more flexible road users that do not follow lane disciple, such as bicyclists, from movements made as a reaction to other road users or obstacles. This can lead to poor calibration of operational behavior models and unrealistic behavior in the simulation. Tactical behavior models recreate the conscious decisions made on a time horizon of seconds to minutes to cope with the immediate traffic situation. As such, tactical behavior models are responsible for selecting the planned path across an intersection.Here, SUMO is coupled with the simulation software DYNA4 to create a simulated road environment for a bicycle simulator. Trajectories observed in reality are displayed as potential prescribed pathways across the simulated intersection. Participants in the simulator study are instructed to select and follow one of the prescribed pathways as closely as possible while responding naturally to other road users and obstacles in the environment. The resulting trajectory data is used to calibrate existing operation al and tactical path finding behavior models for bicyclists at signalized intersection.
Досвід використання замісної ниркової терапії в пацієнтів під час екстракорпоральної мембранної оксигенації
Authors: Chernyshuk S. S. , Vysotskyi A. D. , Adamovska O. A. , Urin O. O. , Zhovnir V. A. 
Published: August 2019

Мета роботи. Проведення на базі одного центру ретроспективного аналізу впливу гострого пошкодження нирок (ГПН) на смертність пацієнтів, яким виконували екстракорпоральну мембранну оксигенацію (ЕКМО).
Матеріали та методи. На базі ДУ «НПМЦ ДКК» у період з 2014 по 2018 рік було проведено 11 процедур ЕКМО. Екстракорпоральну мембранну оксигенацію було розпочато у 7 (64 %) пацієнтів у зв’язку з розвитком гострої серцевої недостатності; у 2 (18 %) – через пневмонію та розвиток гострого респіраторного дистрес-синдрому; в 1 (9 %) пацієнта причиною став сепсис та ще в 1 дитини (9 %) – аритмія. Під час лікування ГПН у наших пацієнтів ми застосовували дві методики: перитонеальний діаліз та модифіковану ультрафільтрацію. Для діалізу використовували розчин «Діавітек ПД» 4,25 % компанії «Юрія-Фарм», для ультрафільтрації – гемоконцентратори Medos® та Terumo®.
Результати та обговорення. Кількість успішних процедур ЕКМО становила 7 (63,5 %) з 11. Ми вважали процедуру ЕКМО успішною, якщо після деканюляції пацієнт прожив протягом 48 год. Із 7 успішно деканюльованих пацієнтів 3 (43 %) були виписані з лікарні.
З 11 пацієнтів в 1 дитини (9 %) функція нирок була збережена, а в 10 (91 %) розвинулося ГПН AKIN3. У зв’язку з ГПН для замісної терапії 6 (55 %) дітям проводили ультрафільтрацію, 1 (9 %) – перитонеальний діаліз; у 3 (27 %) дітей терапію не проводили.
Після запуску ЕКМО ми суттєво покращили кровообіг. За рахунок здійснення ефективної перфузії тканин досягли нормалізації рівня сироваткового лактату на 2-у добу після запуску ЕКМО, діурез відновився на 3-ю–4-у добу, рівень креатиніну знизився на 8–9-у добу.
Усі пацієнти, що перебували на замісній нирковій терапії, мали позитивну динаміку в лікуванні ГПН, але з летальним наслідком за рахунок інших причин. Загальна летальність становила 73 %.
Висновки. Екстракорпоральна мембранна оксигенація – це процедура, що дозволяє проводити доставку кисню в критичних пацієнтів, коли інші методи інтенсивної терапії неефективні. У 90 % пацієнтів, яким виконували ЕКМО, розвинулося ГПН, що потребувало проведення замісної терапії, в тому числі і ультрафільтрації. Гостре пошкодження нирок, що потребує замісної терапії, є предиктором погіршення перебігу захворювання та підвищення летальності в дітей із вродженими вадами серця, які перенесли оперативне втручання з використанням апарату штучного кровообігу. Проведення ультрафільтрації не супроводжувалося розвитком ускладнень та давало змогу отримати від’ємний водний баланс.
Promoting Tuber Formation In Vitro with Benzyl Amino Purine and Paclobutrazol at Different Concentrations
Authors: Suharjo Usman Kris Joko , Hasanudin Hasanudin , Pamekas Tunjung , Pujiwati Hesti , Vanturini Alyi 
Published: August 2019

A common problem related to the production of potatoes in Indonesia is the use of poor quality seed sources and declining seeds. Plant tissue culture is one of the best methods used for the provision of quality seeds. This study aims to establish the best combination of BAP concentration and the concentration of paclobutrazol in spurring the growth of cuttings and initiation of potato tubers in vitro.This research was conducted in November 2017 until June 2018 at Agronomy Laboratory of Biotechnology Division and Plant Culture Network of Agriculture Faculty of Bengkulu University. The research design used was Completely Randomized Design (CRD) which consist of 18 combination of BAP treatment and Paclobutrazol was repeated 6 times. The concentration of BAP used was 0 mg / l, 5 mg / l, 10 mg / l and the concentration of Paclobutrazol 0 mg / l; 2.5 mg / l; 5 mg / l; 7.5 mg / l; 10 mg / l; 12.5 mg / l. The data of the research were analyzed by F test of 5% level and if there were different between treatments followed by Duncan's Multiple Range Test (DMRT) test of5% level. The results showed that the combination of BAP and Paclobutrazol concentration had significant effect on all observed variables. Treatment of 5 mg / l BAP and 7.5 mg / l Paclobutrazol is the best medium in inducing potato micro tube as indicated by the fastest tuber formation time, highest percentage of productive crops, largest number of tubers per bottle, number of tubers per productive plant, tuber diameter the largest and highest wet weight of tuber per bottle. Keywords : in vitro, BAP, paclobutrazol, Potato
Determine the Influence of Social Demography and Access to Information on Giving Consent of Medical Action Toward an Understanding of Informed Consent in Public Hospital With Class C at Pekanbaru.
Authors: Sari Tri Purnama , Jepisah Doni 
Published: August 2019

Informed consent is approval of medical action which is given by the patient or his immediate family after obtaining a complete explanation about medical or dentist action that will be performed on that patient. This study aims to determine the influence of social demography and access to information on giving consent of medical action toward an understanding of informed consent in Public hospital with class C at Pekanbaru. This study employs quantitative method with cross sectional analytic design. The population in this study were all Patient or Families of patient who had received medical treatments in inpatient room for three days before the return of patient as much 267 respondent where the total sample of this research are 194 respondents. The sampling technique is Proportional Random Sampling. Data analysis was carried out in three stages: univariate, bivariate, and multivariate analysis. Based on the result of study found that there was a significant relationship between Education variable (p value 0.007 POR 2,368), work variable (p value 0.042 POR 1,937), age (p value 0.017 POR 2,158), Completeness Information (p value 0.001 POR 2,857), Language Delivery (p value 0.002 POR 2,871) with an understanding of the approval of medical action. Based on the results of multivariate test, it was found that education, completeness of information and language of delivery were the most influential factors.The submission of information must be adjusted to the characteristics of consent provider, especially those related to education, completeness of information and language delivery, so that, if things happen that are not desirable after surgery, the patient or family is expected to receive it because before the surgery is done, the doctor has given an explanation to the patient.
Education and ICT Facilities of Royal Belum Orang Asli School Children
Authors: Haron Habibah Norehan , Harun Hafizah , Dziyauddin Rudzidatul Akmam , Kamaruddin Azlina 
Published: August 2019

An effective teaching and learning using Information and Communication Technology (ICT) is necessary to facilitateÂ students to the easy access world of knowledge. The use of ICT essentially leads to significant impact on a condusive learning environment and also on the studentsâ€™ achievements. In Malaysia, the students come from different background and ethnics, which include orang Asli.Â The urban students might face less difficulties in accepting the ICT in their lessons. A question then raised regarding the readiness of the Orang Asli students, particularly in remote areas, like Royal Belum, Malaysia. This paper investigates the readiness of the primary students, namely from the Jahai group,Â in Royal Belum on the use of ICT devices, such as notepad and laptop. In addition to that, we studied the internet facilities and its connectivity at the schools, including some other related issues. Outcome of the observations showed positive readiness of Orang Asli students in using ICT devices. Nevertheless, a substantial effort from the ICT teachers seems crucial to the effective delivery of the ICT syllabus. Additionally, the schools suffer with slow connectivity as the data rate of 20 Mbps needs to be shared with other nearby schools. This has affected the studentsâ€™ learning and also the teachersâ€™ daily tasks, for instance, in meeting District Education Department (PPD) requirements regarding uploading marks online. Therefore, it is appropriate for the government agencies to search some initiatives in solving the current issues.
Parametric Design process in Architecture
Authors: Wafiqe Saifallah Adel , Alslik Ghada Musa Rzouki 
Published: August 2019

Parametric Design got a good deal of interest and debate since the 90s of the 20th century ,yet this debate increased in size and influence when important buildings in the world by known architects were designed parametrically .These buildings have terms with compositional complexity and smoothness .They characterized the architecture uniqueness and practice since 2000, which caused the academic and theoretical institutions and individuals in architecture to carry on research focusing on parametric design and exploring its activities .Previous studies concentrated on the exploring activity and process of parametric design, accordingly the research problem is identified as follows: The lack of knowledge of parametric design in architecture from the theoretical and detailed sides related to the role of the (architect) , act and process of design , and result of the architectural design .The objectives of the research are : Clarifying the specific knowledge on parametric design in general and in architecture in particular .Clarifying the (thought) aspects of parametric design considering it as a tool or a way of design on an architectural approach .Clarifying the role of (parametric design) and exploring the comparative sides between it and the normal ( traditional ) way of design.
PENERAPAN MODEL PEMBELAJARAN BERBASIS MASALAH UNTUK MENINGKATKAN HASIL BELAJAR IPA
Authors: Okta Puspira Dwi , Yennita Yennita , Ansori Irwandi 
Published: August 2019

Penelitian ini bertujuan untuk mendeskripsikan aktivitas guru dan siswa dalam pembelajaran, serta mendeskripsikan hasil belajar IPA Biologi siswa kelas VIIb SMPN 3 Marga Sakti Seblat dengan penerapan model Pembelajaran Berbasis Masalah (PBM). Penelitian ini merupakan penelitian tindakan kelas (PTK) yang dilakukan dalam dua siklus. Setiap siklus terdiri atas tahap perencanaan, pelaksanaan, tindakan dan refleksi. Subjek penelitian ini adalah guru IPA Biologi sebagai peneliti dan seluruh siswa di kelas VIIb SMPN 3 Marga Sakti Seblat. Instrumen penelitian berupa lembar observasi untuk memperoleh data aktivitas guru dan siswa serta lembar tes untuk memperoleh data hasil belajar siswa. Hasil analisis data observasi aktivitas guru pada siklus 1 diperoleh rerata skor 21 dengan kriteria baik, kemudian meningkat disiklus II skor aktivitas guru meningkat menjadi 22 dengan kriteria baik. Hasil analisis data observasi aktivitas siswa pada siklus 1 diperoleh rerata skor 21 dengan kriteria baik, kemudian meningkat disiklus II menjadi 22 dengan kriteria baik. Presentase ketuntasan belajar klasikal pada siklus I sebesar 47,22 % dengan kriteria belum tuntas, kemudian meningkat pada siklus II menjadi 75 % dengan kriteria tuntas. Dari hasil analisa data tersebut dapat disimpulkan bahwa dengan penerapan model PBM dapat meningkatkan aktivitas guru dan siswa serta hasil belajar IPA Biologi siswa kelas VIIb SMPN 3 Marga Sakti Seblat.Kata kunci: Hasil Belajar, Aktivitas belajar dan mengajar, Pembelajaran Berbasis Masalah
PENERAPAN MODEL KOOPERATIF TIPE JIGSAW UNTUK MENINGKATKAN HASIL BELAJAR IPA-BIOLOGI PADA KONSEP PENCEMARAN LINGKUNGAN KELAS VII
Authors: Carroline Desty , Idrus Irdam , Yennita Yennita 
Published: August 2019

Penelitian ini bertujuan untuk : 1) mendeskripsikan aktivitas mengajar guru dan aktivitas belajar peserta didik, 2) meningkatkan hasil belajar dengan menggunakan model pembelajaran kooperatif tipe Jigsaw dikelas VII.1 SMPN 8 Kota Bengkulu. Jenis penelitian ini adalah PTK dengan metode deskriptif. Penelitian ini terdiri dari 2 siklus, yaitu perencanaan, pelaksanaan, pengamatan dan refleksi. Subjek penelitian guru dan seluruh peserta didik kelas VII.1 SMPN 8 Kota Bengkulu. Instrumen penelitian yang digunakan adalah lembar observasi dan lembar tes. Hasil analisis data observasi aktivitas guru siklus I diperoleh rata-rata skor 27 (Baik), sedangkan pada siklus II meningkat menjadi 29 (Baik). Untuk hasil analisis data observasi aktivitas peserta didik juga mengalami peningkatan dari siklus I diperoleh rata-rata skor 27 (Baik) meningkat menjadi 29 (Baik). Sedangkan untuk presentase ketuntasan belajar klasikal yang diperoleh meningkat dari 65,38% (Belum tuntas) dengan rata-rata 63,15 pada siklus II menjadi 76,92% (Tuntas) dengan rata-rata nilai 75,69.Kata Kunci: Model Kooperatif Tipe Jigsaw, Aktivitas, Hasil BelajarPenelitian ini bertujuan untuk : 1) mendeskripsikan aktivitas mengajar guru dan aktivitas belajar peserta didik, 2) meningkatkan hasil belajar dengan menggunakan model pembelajaran kooperatif tipe Jigsaw dikelas VII.1 SMPN 8 Kota Bengkulu. Jenis penelitian ini adalah PTK dengan metode deskriptif. Penelitian ini terdiri dari 2 siklus, yaitu perencanaan, pelaksanaan, pengamatan dan refleksi. Subjek penelitian guru dan seluruh peserta didik kelas VII.1 SMPN 8 Kota Bengkulu. Instrumen penelitian yang digunakan adalah lembar observasi dan lembar tes. Hasil analisis data observasi aktivitas guru siklus I diperoleh rata-rata skor 27 (Baik), sedangkan pada siklus II meningkat menjadi 29 (Baik). Untuk hasil analisis data observasi aktivitas peserta didik juga mengalami peningkatan dari siklus I diperoleh rata-rata skor 27 (Baik) meningkat menjadi 29 (Baik). Sedangkan untuk presentase ketuntasan belajar klasikal yang diperoleh meningkat dari 65,38% (Belum tuntas) dengan rata-rata 63,15 pada siklus II menjadi 76,92% (Tuntas) dengan rata-rata nilai 75,69.Kata Kunci: Model Kooperatif Tipe Jigsaw, Aktivitas, Hasil Belajar
PENINGKATAN HASIL BELAJAR PESERTA DIDIK MELALUI PENERAPAN MODEL PEMBELAJARAN BERBASIS MASALAH
Authors: Kausar Lafil , Idrus Irdam , Jumiarni Dewi 
Published: August 2019

Penelitian ini bertujuan untuk mendeskripsikan aktivitas mengajar guru, aktivitas belajar peserta didik, dan meningkatkan hasil belajar peserta didik dengan menggunakan model Pembelajaran Berbasis Masalah (PBM) di Kelas VIIIA SMPN 05 Mukomuko. Jenis penelitian ini adalah Penelitian Tindakan Kelas dengan metode deskriptif. Penelitian ini terdiri dari dua siklus, masing-masing siklus terdiri dari 4 tahap yaitu: tahap perencanaan, pelaksanaan, pengamatan dan refleksi. Subjek penelitian ini adalah guru dan seluruh peserta didik kelas VIIIA SMPN 05 Mukomuko. Instrumen penelitian yang digunakan adalah lembar tes dan lembar observasi, lembar observasi terdiri dari lembar observasi guru dan peserta didik. Pada siklus I aktivitas mengajar guru diperoleh skor rata-rata yaitu 29 (Baik) dan pada siklus II skor aktivitas guru menjadi 32 (Baik). Pada siklus I aktivitas belajar peserta didik diperoleh skor rata-rata yaitu 29 (Baik) dan pada siklus II skor aktivitas belajar peserta didik menjadi 32 (Baik). Hasil analisis persentase ketuntasan belajar peserta didik pada siklus I yaitu 66,67% (tidak tuntas) dan pada siklus II meningkat menjadi 88,89% (tuntas). Dari hasil penelitian dapat disimpulkan bahwa model PBM dapat meningkatkan aktivitas guru dan peserta didik serta hasil belajar peserta didik kelas VIIIA SMPN 05 Mukomuko.Kata Kunci: Pembelajaran Berbasis Masalah, Aktivitas dan Hasil Belajar.
PEMAHAMAN KONSEP BRYOPHYTA DENGAN MENGGUNAKAN LKPD BERBASIS OBSERVASI PADA PESERTA DIDIK KELAS X SMAN 1 ARGAMAKMUR
Authors: Farida Nur , Karyadi Bhakti , Kasrina Kasrina 
Published: August 2019

Penelitian ini bertujuan untuk mengetahui kelayakan LKPD, dan kemampuan pemahaman konsep keanekaragaman Bryophyta pada peserta didik kelas X SMA. Jenis penelitian ini adalah penelitian dan pengembangan. Metode penelitian yang digunakan adalah R & D dengan mengadopsi langkah-langkah dari Borg & Gall. Subyek penelitian 26 orang peserta didik kelas X IPA3 SMA negeri 1 Argamakmur. Variabel penelitian adalah kemampuan pemahaman konsep peserta didik tentang keanekaragaman Bryophyta. Instrumen yang digunakan untuk megukur kemampuan pemahaman konsep dalam bentuk tes esai yang terdiri dari indikator translasi, interpretasi, dan ekstrapolasi. Hasil validasi ahli dan praktisi, LKPD yang dikembangkan dinyatakan sangat valid dengan persentase mencapai 87%. kemampuan pemahaman konsep peserta didik setelah belajar dengan LKPD menunjukkan peningkatan dengan rerata nilai pretest-posttest 65,9 menjadi 78,6. Pembelajaran biologi dengan menggunakan LKPD berdasarkan hasil studi keanekaragaman tumbuhan lumut disekitar lingkungan siswa dapat meningkatkan kemampuan pemahaman konsep peserta didik kelas X SMA 1 Argamakmur.Kata kunci : LKPD, keanekaragaman bryophyta, pemahaman konsep
Antibiotic exposure and ‘response failure’ for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care
Authors: van Hecke Oliver , Fuller Alice , Bankhead Clare , Jenkins-Jones Sara , Francis Nick , Moore Michael , Butler Chris , Wang Kay 
Published: August 2019

BackgroundChildhood antibiotic exposure has important clinically relevant implications. These include disruption to the microbiome, antibiotic resistance, and clinical workload manifesting as treatment ‘failure’.AimTo examine the relationship between the number of antibiotic courses prescribed to preschool children for acute respiratory tract infections (RTI), in the preceding year, and subsequent RTIs that failed to respond to antibiotic treatment (‘response failures’).Design and settingA cohort study using UK primary care data from the Clinical Practice Research Datalink, 2009 to 2016.MethodChildren aged 12 to 60 months (1 to 5 years) who were prescribed an antibiotic for an acute RTI (upper and lower RTI or otitis media) were included. One random index antibiotic course for RTI per child was selected. Exposure was the number of antibiotic prescriptions for acute RTI up to 12 months before the index antibiotic prescription. The outcome was ‘response failure’ up to 14 days after index antibiotic prescription, defined as: subsequent antibiotic prescription; referral; hospital admission; death; or emergency department attendance within 3 days. The authors used logistic regression models to estimate the odds between antibiotic exposure and response failure.ResultsOut of 114 329 children who were prescribed an antibiotic course for acute RTI, children who received ≥2 antibiotic courses for acute RTIs in the preceding year had greater odds of response failure; one antibiotic course: adjusted odds ratio (OR) 1.03 (95% confidence interval [CI] = 0.88 to 1.21), P = 0.67, n = 230 children; ≥2 antibiotic courses: adjusted OR 1.32 (CI = 1.04 to 1.66), P = 0.02, n = 97.ConclusionChildhood antibiotic exposure for acute RTI may be a good predictor for subsequent response failure (but not necessarily because of antibiotic treatment failure). Further research is needed to improve understanding of the mechanisms underlying response failure.
Patient preferences for management of high blood pressure in the UK: a discrete choice experiment
Authors: Fletcher Benjamin , Hinton Lisa , McManus Richard , Rivero-Arias Oliver 
Published: August 2019

BackgroundWith a variety of potentially effective hypertension management options, it is important to determine how patients value different models of care, and the relative importance of factors in their decision-making process.AimTo explore patient preferences for the management of hypertension in the UK.Design and settingOnline survey of patients who have hypertension in the UK including an unlabelled discrete choice experiment (DCE).MethodA DCE was developed to assess patient preferences for the management of hypertension based on four attributes: model of care, frequency of blood pressure (BP) measurement, reduction in 5-year cardiovascular risk, and costs to the NHS. A mixed logit model was used to estimate preferences, willingness-to-pay was modelled, and a scenario analysis was conducted to evaluate the impact of changes in attribute levels on the uptake of different models of care.ResultsOne hundred and sixty-seven participants completed the DCE (aged 61.4 years, 45.0% female, 82.0% >5 years since diagnosis). All four attributes were significant in choice (P<0.05). Reduction in 5-year cardiovascular risk was the main driver of patient preference as evidenced in the scenario and willingness-to-pay analyses. GP management was significantly preferred over self-management. Patients preferred scenarios with more frequent BP measurement, and lower costs to the NHS.ConclusionParticipants had similar preferences for GP management, pharmacist management, and telehealth, but a negative preference for self-management. When introducing new models of care for hypertension to patients, discussion of the potential benefits in terms of risk reduction should be prioritised to maximise uptake.
Bone scintigraphy imaging of cardiac amyloidosis
Authors: Kuria Issa Menge , Gitau Samuel Nguku , Makhdomi Khalid Bashir 
Published: August 2019

AbstractTransthyretin-related cardiac amyloidosis (ATTR) amyloidosis is an aggressive, rapidly progressive, and fatal disease, for which several promising therapies are in development. This condition is frequently underdiagnosed because of the limited specificity of echocardiography and the traditional requirement for histological diagnosis. It is well known that 99mtechnetium-labeled bone scan radiotracers can localize in the myocardial amyloid deposits, but the use of this imaging modality to differentiate between the two subtypes has only lately been revisited. We report a case of a 76-year-old man with a clinical diagnosis of amyloidosis who underwent a bone scan that had features of ATTR amyloidosis. To the best of our knowledge, this is the first case report in Sub-Saharan Africa.