bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hitos de la evaluación perceptual auditiva de la voz: ¿Hay evidencia?
Authors: Angel Gordillo Luisa Fernanda 
Published: April 2019

La evaluación perceptual auditiva es la herramienta más antigua y con mayor uso para determinar la idoneidad de la voz humana. Como resultado de una revisión minuciosa en PubMed se identifica que este enfoque ha evolucionado en lo conceptual y lo metodológico enmarcado en tres momentos: el primero caracterizado por el uso indiscriminado de etiquetas particulares, el segundo centrado en la construcción y refinamiento de escalas con confiabilidad intra e interevaluador, y a futuro, su posicionamiento como un estándar de oro que exalta los determinantes humanos y sociales de la voz. Las escalas más utilizadas en las investigaciones fueron GRBAS y CAPE-V. Adicionalmente, se argumenta la idoneidad de los vocablos más apropiados en idioma español para la denominación de “voice quality” equiparable a cualidad vocal (indicador descriptivo multidimensional) o calidad vocal (valoración de severidad) según corresponda.
Bioequivalence metrics for absorption rates: linearity, specificity, sensitivity
Authors: Vincze István , Endrényi László , Tóthfalusi László 
Published: April 2019

Aims:In order to ensure the therapeutic equivalence of generic products, it would be important to contrast measures additional to Cmax in order to assess differences in absorption rates. Our aim was to compare partial AUC (PAUC), Swing, and PTF to Cmax in terms of sensitivity, specificity and linearity under identical kinetic conditions.
Methods:Single-dose and multiple-dose concentration curves were generated assuming one-compartment models. Kinetic sensitivity curves were obtained by gradually changing the absorption rate constant and keeping all other parameters fixed.
Results:A metric should reflect specifically the investigated kinetic feature (e.g., the rate of absorption), be linearly related to it, and should exhibit high kinetic sensitivity. Cmax is related nonlinearly to the rate of absorption, is nonspecific to it (reflects also the extent of absorption as well as the rates of disposition processes), lacks kinetic sensitivity even following a single administration. Compared to Cmax, PAUC was always more sensitive under every investigated condition. Swing and PTF showed high kinetic sensitivity but, in contrast to PAUC, they could be evaluated only in multiple-dose studies.
Conclusion:Under identical conditions, different metrics provide widely differing point estimates. Differences in kinetic sensitivity among bioequivalence metrics should be accounted for when results of different metrics are compared.
Elke Donalies (2018): "Wetterbeobachter, Zeitlang, wahrsagen, zartfühlend, kurzerhand, dergestalt."
Authors: Telschow Claudia 
Published: April 2019

In ihrer neuesten Publikation befasst sich die ausgewiesene Wortbildungsexpertin Elke Donalies mit Fällen wie Wetterbeobachter, Dickhäuter, Vergissmeinnicht, zartfühlend und wieviel, deren linguistische Erfassung nach wie vor Probleme bereitet. Grund dafür dürfte zum einen sein, dass die Worthaftigkeit der untersuchten Einheiten vielfach fraglich ist (z. B. zart fühlend als syntaktische Fügung vs. zartfühlend als Wort bzw. Wortbildungsprodukt). Zum anderen ist die Analyse der Einheiten – bei Zuordnung zum Bereich Wortbildung – schwierig und im Resultat entsprechend vielfältig (z. B. Dickhäuter als Derivation, Zusammenbildung oder synthetic compound (vgl. S. 114)). Donalies hat sich also mit der Wahl derartiger "linguistischer Problemmacher" viel vorgenommen und insgesamt drei Jahre Projektzeit im Rahmen ihrer IDS-Tätigkeit dafür aufgewendet (Januar 2015–Januar 2018).

Dieser Beitrag ist ursprünglich im Peter-Lang-Verlag erschienen (https://www.ingentaconnect.com/contentone/plg/jwf/2019/00000003/00000001/art00003)
Persistent Quasi-periodic Pulsations during a Large X-class Solar Flare
Authors: Hayes Laura A. , Gallagher Peter T. , Dennis Brian R. , Ireland Jack , Inglis Andrew , Morosan Diana E. 
Published: April 2019

Abstract
Solar flares often display pulsating and oscillatory signatures in the emission, known as quasi-periodic pulsations (QPP). QPP are typically identified during the impulsive phase of flares, yet in some cases, their presence is detected late into the decay phase. Here, we report extensive fine structure QPP that are detected throughout the large X8.2 flare from 2017 September 10. Following the analysis of the thermal pulsations observed in the Geostationary Operational Environmental Satellite/X-ray sensor and the 131 Å channel of Solar Dynamics Observatory/Atmospheric Imaging Assembly, we find a pulsation period of ∼65 s during the impulsive phase followed by lower amplitude QPP with a period of ∼150 s in the decay phase, up to three hours after the peak of the flare. We find that during the time of the impulsive QPP, the soft X-ray source observed with the Reuven Ramaty High Energy Solar Spectroscopic Imager rapidly rises at a velocity of approximately 17 km s−1 following the plasmoid/coronal mass ejection eruption. We interpret these QPP in terms of a manifestation of the reconnection dynamics in the eruptive event. During the long-duration decay phase lasting several hours, extended downward contractions of collapsing loops/plasmoids that reach the top of the flare arcade are observed in EUV. We note that the existence of persistent QPP into the decay phase of this flare are most likely related to these features. The QPP during this phase are discussed in terms of magnetohydrodynamic wave modes triggered in the post-flaring loops.
IDP-like Asteroids Formed Later than 5 Myr After Ca–Al-rich Inclusions
Authors: Neveu Marc , Vernazza Pierre 
Published: April 2019

Abstract
The parent bodies of ordinary chondrites, carbonaceous CM chondrites, and interplanetary dust particles (IDPs) represent most of the mass of the solar system’s small (D ≤ 250 km) bodies. The times of formation of the ordinary and carbonaceous CM chondrite parent bodies have previously been pinpointed, respectively, to ≈2 and 3–4 million years after calcium–aluminum-rich inclusions (CAIs). However, the timing of the formation of IDP parent bodies such as P- and D-type main-belt asteroids and Jupiter Trojans has not been tightly constrained. Here, we show that they formed later than 5–6 million years after CAIs. We use models of their thermal and structural evolution to show that their anhydrous surface composition would otherwise have been lost due to melting and ice-rock differentiation driven by heating from the short-lived radionuclide 26Al. This suggests that IDP-like volatile-rich small bodies may have formed after the gas of the protoplanetary disk dissipated and thus later than the massive cores of the giant planets. It also confirms an intuitive increase in formation times with increased heliocentric distance, and suggests that there may have been a gap in time between the formation of carbonaceous chondrite (chondrule-rich) and IDP (chondrule-poor) parent bodies.
A Spectroscopic Analysis of the California-Kepler Survey Sample. I. Stellar Parameters, Planetary Radii, and a Slope in the Radius Gap
Authors: Martinez Cintia F. , Cunha Katia , Ghezzi Luan , Smith Verne V. 
Published: April 2019

Abstract
We present results from a quantitative spectroscopic analysis conducted on archival Keck/HIRES high-resolution spectra from the California-Kepler Survey (CKS) sample of transiting planetary host stars identified from the Kepler mission. The spectroscopic analysis was based on a carefully selected set of Fe i and Fe ii lines, resulting in precise values for the stellar parameters of effective temperature (T
eff) and surface gravity (log g). Combining the stellar parameters with Gaia DR2 parallaxes and precise distances, we derived both stellar and planetary radii for our sample, with a median internal uncertainty of 2.8% in the stellar radii and 3.7% in the planetary radii. An investigation into the distribution of planetary radii confirmed the bimodal nature of this distribution for the small-radius planets found in previous studies, with peaks at ∼1.47 ± 0.05 and ∼2.72 ± 0.10 R
⊕ with a gap at ∼1.9 R
⊕. Previous studies that modeled planetary formation that is dominated by photoevaporation predicted this bimodal radii distribution and the presence of a radius gap, or photoevaporation valley. Our results are in overall agreement with these models, as well as core powered mass-loss models. The high internal precision achieved here in the derived planetary radii clearly reveal the presence of a slope in the photoevaporation valley for the CKS sample, indicating that the position of the radius gap decreases with orbital period; this decrease was fit by a power law of the form R
pl ∝ P
−0.11, which is consistent with both photoevaporation and core powered mass-loss models of planet formation, with Earth-like core compositions.
A Readability Analysis of Online Cardiovascular Disease-Related Health Education Materials
Authors: Ayyaswami Varun , Padmanabhan Divya , Patel Manthan , Prabhu Arpan Vaikunth , Hansberry David R. , Agarwal Nitin , Magnani Jared W. 
Published: April 2019

Background:
Online cardiovascular health materials are easily accessible with an Internet connection, but the readability of its content may limit practical use by patients.

Objective:
The goal of our study was to assess the readability of the most commonly searched Internet health education materials for cardiovascular diseases accessed via Google.

Methods:
We selected 20 commonly searched cardiovascular disease terms: aneurysm, angina, atherosclerosis, cardiomyopathy, congenital heart disease, coronary artery disease, deep vein thrombosis, heart attack, heart failure, high blood pressure, pericardial disease, peripheral arterial disease, rheumatic heart disease, stroke, sudden death, valvular heart disease, mini-stroke, lower extremity edema, pulmonary embolism, and exertional dyspnea. Terms were selected on Google and selected up to 10 results in order of presentation in the search results by reviewing a maximum of 15 pages of Google search results specifically providing education toward patients to yield 196 total patient education articles.

Key Results:

All readability measures assessing grade level measures found the 196 articles were written at a mean 10.9 (
SD
= 1.8) grade reading level. Moreover, 99.5% of the articles were written beyond the 5th- to 6th-grade level recommended by the American Medical Association.

Conclusions:

Given the prominent use of online patient education material, we consider readability as a quality metric that should be evaluated prior to online publication of any health education materials. Further study of how to improve the readability of online materials may enhance patient education, engagement, and health outcomes.

[
HLRP: Health Literacy Research and Practice
. 2019;3(2):e74–e80.]

Plain Language Summary:
Patients often use Google as a tool for understanding their medical conditions. This study examined the readability of articles accessed via Google for commonly searched cardiovascular diseases and found all articles were written above reading grade levels appropriate for patients. We hope this study will promote the importance of ensuring that online patient education articles are written at appropriate reading levels.
Cutting Edge: Polymicrobial Sepsis Has the Capacity to Reinvigorate Tumor-Infiltrating CD8 T Cells and Prolong Host Survival
Authors: Danahy Derek B. , Jensen Isaac J. , Griffith Thomas S. , Badovinac Vladimir P. 
Published: April 2019

AbstractMalignancy increases sepsis incidence 10-fold and elevates sepsis-associated mortality. Advances in treatment have improved survival of cancer patients shortly after sepsis, but there is a paucity of information on how sepsis impacts cancer growth, development, and prognosis. To test this, cecal ligation and puncture surgery was performed on B16 melanoma-bearing mice to show that sepsis has detrimental effects in hosts with advanced tumors, leading to increased mortality. Surprisingly, mice experiencing cecal ligation and puncture–induced sepsis earlier during tumor development exhibited CD8 T cell–dependent attenuation of tumor growth. Sepsis-resistant CD8 tumor-infiltrating T cells showed increased in vivo activation, effector IFN-γ cytokine production, proliferation, and expression of activation/inhibitory PD-1/LAG-3 receptors because of a sepsis-induced liberation of tumor Ags. Sepsis-reinvigorated CD8 tumor-infiltrating T cells were also amenable to (anti–PD-L1/LAG-3) checkpoint blockade therapy, further prolonging cancer-associated survival in sepsis survivors. Thus, sepsis has the capacity to improve tumor-specific CD8 T cell responses, leading to better cancer prognosis and increased survival.
Novel aerosol extinction coefficients and lidar ratios over the ocean from CALIPSO–CloudSat: evaluation and global statistics
Authors: Painemal David , Clayton Marian , Ferrare Richard , Burton Sharon , Josset Damien , Vaughan Mark 
Published: April 2019

Abstract. Aerosol extinction coefficients (σa) and lidar ratios
(LRs) are retrieved over the ocean from CALIPSO's Cloud-Aerosol Lidar with
Orthogonal Polarization (CALIOP) attenuated backscatter profiles by solving
the lidar equation constrained with aerosol optical depths (AODs) derived by
applying the Synergized Optical Depth of Aerosols (SODA) algorithm to ocean
surface returns measured by CALIOP and CloudSat's Cloud Profiling Radar.
σa and LR are retrieved for two independent scenarios that
require somewhat different assumptions: (a) a single homogeneous atmospheric
layer (1L) for which the LR is constant with height and (b) a vertically
homogeneous layer with a constant LR overlying a marine boundary layer with
a homogenous LR fixed at 25 sr (two-layer method, 2L). These new retrievals
differ from the standard CALIPSO version 4.1 (V4) product, as the
CALIOP–SODA method does not rely on an aerosol classification scheme to
select LR. CALIOP–SODA σa and LR are evaluated using airborne
high-spectral-resolution lidar (HSRL) observations over the northwest
Atlantic. CALIOP–SODA LR (1L and 2L) positively correlates with its HSRL
counterpart (linear correlation coefficient r>0.67), with a
negative bias smaller than 17.4 % and a good agreement for σa
(r≥0.78) with a small negative bias (≤|-9.2%|).
Furthermore, a global comparison of optical depths derived by CALIOP–SODA
and CALIPSO V4 reveals substantial discrepancies over regions dominated by
dust and smoke (0.24), whereas Aqua's Moderate resolution Imaging
Spectroradiometer (MODIS) and SODA AOD regional differences are within 0.06. Global maps of CALIOP–SODA LR feature high values over littoral zones,
consistent with expectations of continental aerosol transport offshore. In
addition, seasonal transitions associated with biomass burning from June
to October over the southeast Atlantic are well reproduced by CALIOP–SODA
LR.
A modified seasonal cycle during MIS31 super-interglacial favors stronger interannual ENSO and monsoon variability
Authors: Justino Flavio , Kucharski Fred , Lindemann Douglas , Wilson Aaron , Stordal Frode 
Published: April 2019

Abstract. It has long been recognized that the amplitude of the seasonal cycle can
substantially modify climate features in distinct timescales. This study
evaluates the impact of the enhanced seasonality characteristic of the Marine
Isotope Stage 31 (MIS31) on the El Niño–Southern Oscillation (ENSO). Based
upon coupled climate simulations driven by present-day
(CTR) and MIS31 boundary
conditions, we demonstrate that the CTR simulation shows a significant
concentration of power in the 3–7-year band and on the multidecadal
timescale between 15 and 30 years. However, the MIS31 simulation shows
drastically modified temporal variability of the ENSO, with stronger power
spectrum at interannual timescales but the absence of decadal periodicity.
Increased meridional gradient of sea surface temperature (SST) and wind
stress in the Northern Hemisphere subtropics are revealed to be the primary
candidates responsible for changes in the equatorial variability. The oceanic
response to the MIS31 ENSO extends to the extratropics, and fits nicely with
SST anomalies delivered by paleoreconstructions. The implementation of the
MIS31 conditions results in a distinct global monsoon system and its link to
the ENSO in respect to current conditions. In particular, the Indian monsoon
intensified but no correlation with ENSO is found in the MIS31 climate,
diverging from conditions delivered by our current climate in which this
monsoon is significantly correlated with the NIÑO34 index. This indicates
that monsoonal precipitation for this interglacial is more closely connected
to hemispherical features than to the tropical–extratropical climate
interaction.
A 2700-year annual timescale and accumulation history for an ice core from Roosevelt Island, West Antarctica
Authors: Winstrup Mai , Vallelonga Paul , Kjær Helle A. , Fudge Tyler J. , Lee James E. , Riis Marie H. , Edwards Ross , Bertler Nancy A. N. , Blunier Thomas , Brook Ed J. , Buizert Christo , Ciobanu Gabriela , Conway Howard , Dahl-Jensen Dorthe , Ellis Aja , Emanuelsson B. Daniel , Hindmarsh Richard C. A. , Keller Elizabeth D. , Kurbatov Andrei V. , Mayewski Paul A. , Neff Peter D. , Pyne Rebecca L. , Simonsen Marius F. , Svensson Anders , Tuohy Andrea , Waddington Edwin D. , Wheatley Sarah 
Published: April 2019

Abstract. We present a 2700-year annually resolved chronology and snow accumulation
history for the Roosevelt Island Climate Evolution (RICE) ice core, Ross Ice
Shelf, West Antarctica. The core adds information on past accumulation
changes in an otherwise poorly constrained sector of Antarctica. The timescale was constructed by identifying annual cycles in
high-resolution impurity records, and it constitutes the top part of the
Roosevelt Island Ice Core Chronology 2017 (RICE17). Validation by volcanic
and methane matching to the WD2014 chronology from the WAIS Divide ice core
shows that the two timescales are in excellent agreement. In a companion
paper, gas matching to WAIS Divide is used to extend the timescale for the
deeper part of the core in which annual layers cannot be identified. Based on the annually resolved timescale, we produced a record of past snow
accumulation at Roosevelt Island. The accumulation history shows that
Roosevelt Island experienced slightly increasing accumulation rates between
700 BCE and 1300 CE, with an average accumulation of 0.25±0.02 m
water equivalent (w.e.) per year. Since 1300 CE, trends in the accumulation
rate have been consistently negative, with an acceleration in the rate of
decline after the mid-17th century. The current accumulation rate at
Roosevelt Island is 0.210±0.002 m w.e. yr−1 (average since 1965 CE, ±2σ), and it is rapidly declining with a trend corresponding to
0.8 mm yr−2. The decline observed since the mid-1960s is 8 times faster
than the long-term decreasing trend taking place over the previous
centuries, with decadal mean accumulation rates consistently being below
average. Previous research has shown a strong link between Roosevelt Island
accumulation rates and the location and intensity of the Amundsen Sea Low,
which has a significant impact on regional sea-ice extent. The decrease in
accumulation rates at Roosevelt Island may therefore be explained in terms
of a recent strengthening of the ASL and the expansion of sea ice in the eastern
Ross Sea. The start of the rapid decrease in RICE accumulation rates
observed in 1965 CE may thus mark the onset of significant increases in
regional sea-ice extent.
Hydrometeorological data from Marmot Creek Research Basin, Canadian Rockies
Authors: Fang Xing , Pomeroy John W. , DeBeer Chris M. , Harder Phillip , Siemens Evan 
Published: April 2019

Abstract. Meteorological, snow survey, streamflow, and groundwater data are presented
from Marmot Creek Research Basin, Alberta, Canada. The basin is a
9.4 km2, alpine–montane forest headwater catchment of the Saskatchewan
River basin that provides vital water supplies to the Prairie Provinces of
Canada. It was heavily instrumented, experimented upon, and operated by
several federal government agencies between 1962 and 1986, during which time
its main and sub-basin streams were gauged, automated meteorological stations
at multiple elevations were installed, groundwater observation wells were dug
and automated, and frequent manual measurements of snow accumulation and
ablation and other weather and water variables were made. Over this period,
mature evergreen forests were harvested in two sub-basins, leaving large
clear cuts in one basin and a “honeycomb” of small forest clearings in
another basin. Whilst meteorological measurements and sub-basin streamflow
discharge weirs in the basin were removed in the late 1980s, the federal
government maintained the outlet streamflow discharge measurements and a
nearby high-elevation meteorological station, and the Alberta provincial
government maintained observation wells and a nearby fire weather station.
Marmot Creek Research Basin was intensively re-instrumented with 12 automated
meteorological stations, four sub-basin hydrometric sites, and seven snow
survey transects starting in 2004 by the University of Saskatchewan Centre
for Hydrology. The observations provide detailed information on meteorology,
precipitation, soil moisture, snowpack, streamflow, and groundwater during
the historical period from 1962 to 1987 and the modern period from 2005 to
the present time. These data are ideal for monitoring climate change,
developing hydrological process understanding, evaluating process algorithms
and hydrological, cryospheric, or atmospheric models, and examining the
response of basin hydrological cycling to changes in climate, extreme
weather, and land cover through hydrological modelling and statistical
analyses. The data presented are publicly available from Federated Research
Data Repository (https://doi.org/10.20383/101.09, Fang et al., 2018).
Πίστις and Πιστεύω in Romans 4:5: Neglected Evidence for “Faith in Christ,” and a Re-detheologizing of the Πίστις Χριστοῦ Debate
Authors: Jensen Aaron Michael 
Published: April 2019

ABSTRACT
This article resolves the Πίστις Χριστοῦ debate in favor of the “faith in Christ” interpretation, first by drawing from Rom 4:5 the necessary evidence to link πιστεύω with Paul’s use of πίστις in the πίστις Χριστοῦ phrases and second by demonstrating that πίστις is polysemous with respect to its meanings “faith” and “faithfulness.”
Ἐπὶ Ποντίου Πιλάτου in 1 Timothy 6:13 and Ante-Nicene Christian Literature
Authors: Judd Frank F. 
Published: April 2019

ABSTRACT
This study examines the use of the Greek phrase ἐπὶ Ποντίου Πιλάτου in 1 Tim 6:13 and ante-Nicene Christian literature. Although many scholars understand ἐπὶ Ποντίου Πιλάτου in 1 Tim 6:13 in a temporal sense (“in the time of Pontius Pilate”)—as it is typically understood in subsequent Christian literature and the creeds—or in a simple locative sense (“in the presence of Pontius Pilate”), this study argues through a detailed grammatical analysis that the occurrence of ἐπὶ Ποντίου Πιλάτου in 1 Tim 6:13 should more accurately be understood in a legal/declarative sense (“before Pontius Pilate”).