bluuebunny/crossref_metadata_2025_split huggingface dataset:
Jagdish N. Sheth: reflections of an accidental scholar
Authors: Sheth Jagdish 
Published: May 2019

Purpose
The aim of this paper is to demonstrate that scholarship is all about challenging the prevailing wisdom by offering an alternative perspective or explanation. Hopefully, the author’s journey of more than 50 years will inspire others to be eclectic and become deep generalists.

Design/methodology/approach
It is an autobiographical evaluation of an accidental scholar. It emphasizes that an educator is more than a scientist or a priest or a public servant. It is all of them. Educators are in the business of making ordinary people extraordinary. They are diamond cutters who are entrusted by society with its rough diamonds to get their brilliance out and make them useful to themselves, the society and the community.

Findings
Over 50 years, marketing has evolved and adapted to the external environment, including technology revolution, changing demographics, global competition and geopolitics. This provides enormous opportunity for the next generation of scholars to establish their own identity in managerial marketing, consumer behavior or marketing analytics.

Practical implications
While publishing in the top journals is both necessary and desirable in the early stages of an academic career, it is also important to make an impact on practitioners by publishing professional books.

Social implications
According to Peter Drucker, there are only two functions of business: innovation and marketing. While innovation is admired by everyone, marketing can also become a positive force for a better world.

Originality/value
Lessons learnt over time from different encounters and circumstances in research, teaching and service are important to document. In the end, according to the author, they are all academic entrepreneurs.
Ruby Roy Dholakia: autobiographical reflections of a female marketing academic
Authors: Dholakia Ruby Roy 
Published: May 2019

Purpose
In a very personal reflection, this paper aims to trace the academic trajectory of a female marketing academic in a very male-dominated discipline. It also highlights the struggle balancing work and family, as well as protecting an immigrant identity in a foreign culture.

Design/methodology/approach
Given the period and unique conditions of the author’s academic journey, this highly personal retrospective account is based on recall of significant events that have shaped my singular experience. It attempts to capture the experience of an immigrant female novice navigating not only a foreign culture but also a very male-dominant discipline.

Findings
While times have changed and gender barriers are lower today, challenges remain. In addition, the set of choices faced by women with partners in the same discipline differ significantly and complicate the family-work balance decisions. There is no one set of path that can be followed.

Practical implications
While there is a professional cost to deviating from the mainstream, pursuing alternatives to the dominant topics is vital to advancing the health and relevance of the marketing discipline. The relationships between marketing and development have been an important topic for me; however, these macromarketing topics continue to be neglected. Given the current socio-economic-political conditions globally, perhaps future marketing scholars will devote greater attention to these topics.

Originality/value
This is purely the author’s personal reflection of a journey that began accidentally. It also occurred in the 1970s when women were rare in the business world, particularly business academia. It offers a retrospective comparison to male peers who, aside from their individual talents and history (Belk, 2017; Firat, 2014; Holbrook, 2017), were achieving their professional goals at a similar period. It also provides some historical context that can be compared to experiences of other female pioneers in marketing academia and marketing practice (Bolton, 2017; Tadajewski and Maclaran, 2013; Zeithaml, 2017).
Focal skeletal FDG uptake indicates poor prognosis in cHL regardless of extent and first‐line chemotherapy
Authors: Pedersen Mette A. , Gormsen Lars C. , Kamper Peter , Wassberg Cecilia , Andersen Maja D. , d'Amore Alexander L. , Barrington Sally F. , Johnson Peter , Hamilton‐Dutoit Stephen , Amini Rose‐Marie , Enblad Gunilla , Molin Daniel , d'Amore Francesco 
Published: May 2019

Summary18F‐fluoro‐2‐deoxy‐D‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) is used for staging classical Hodgkin lymphoma (cHL) with high sensitivity for skeletal involvement. However, it is unclear whether a single bone lesion carries the same adverse prognosis as multifocal lesions and if this is affected by type of chemotherapy [ABVD (adriamycin, bleomycin, vincristine, dacarbazine) versus BEACOPP (bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, prednisone)]. We reviewed the clinico‐pathological and outcome data from 209 patients with newly diagnosed cHL staged by FDG‐PET/CT. Patterns of skeletal/bone marrow uptake (BMU) were divided into ‘low’ and ‘high’ diffuse BMU (i.e. without focal lesions), and unifocal or multifocal lesions. Additional separate survival analysis was performed, taking type of chemotherapy into account. Forty patients (19·2%) had skeletal lesions (20 unifocal, 20 multifocal). The 3‐year progression‐free‐survival (PFS) was 80% for patients with ‘low BMU’, 87% for ‘high BMU’, 69% for ‘unifocal’ and 51% for ‘multifocal’ lesions; median follow‐up was 38 months. The presence of bone lesions, both uni‐ and multifocal, was associated with significantly inferior PFS (log rank P = 0·0001), independent of chemotherapy type. Thus, increased diffuse BMU should not be considered as a risk factor in cHL, whereas unifocal or multifocal bone lesions should be regarded as important predictors of adverse outcome, irrespective of the chemotherapy regimen used.
Second allogeneic stem cell transplantation in patients with acute lymphoblastic leukaemia: a study on behalf of the Acute Leukaemia Working Party of the European Society for Blood and Marrow Transplantation
Authors: Nagler Arnon , Labopin Myriam , Dholaria Bhagirathbhai , Finke Jürgen , Brecht Arne , Schanz Urs , Niittyvuopio Riitta , Neubauer Andreas , Bornhäuser Martin , Santarone Stella , Beelen Dietrich , Shimoni Avichai , Rösler Wolf , Giebel Sebastian , Savani Bipin N. , Mohty Mohamad 
Published: May 2019

SummaryAlthough second allogeneic haematopoietic cell transplantation (allo‐HCT2) is a therapeutic option for patients relapsing after first HCT (allo‐HCT1), there is limited data on allo‐HCT2 in patients with acute lymphoblastic leukaemia (ALL).We retrospectively studied 245 patients receiving allo‐HCT2 as a salvage treatment for relapse following allo‐HCT1 between the 2000 and 2017. The median age at allo‐HCT2 was 34·6 years (range: 18–74). One hundred and one patients (41%) received sibling donor and 144 (59%) unrelated donor allo‐HCT2. Acute graft‐versus‐host disease (GVHD) grade II–IV and III–IV occurred in 33% and 17% of the patients, respectively. The incidence of 2‐year total and extensive chronic GVHD was 38% and 19%, respectively. The 2‐ and 5‐year cumulative incidence of non‐relapse mortality, relapse incidence, leukaemia‐free survival, overall survival and GVHD‐free, relapse‐free survival (GRFS) were 24% and 26%, 56% and 62%, 20% and 12%, 30% and 14% and 12% & 7%, respectively. In multivariate analysis, factors associated with overall survival were age, time from allo‐HCT1 to relapse, conditioning for allo‐HCT1, Karnofsky score at allo‐HCT2 and donor type for allo‐HCT2. In conclusion, outcomes of allo‐HCT2 in ALL patients were poor, with only 14% overall survival and 7% GRFS at 5 years with very high relapse incidence.
Reinduktion zielgerichteter Therapie beim metastasierten Melanom
Authors: Reschke Robin , Simon Jan‐Christoph , Ziemer Mirjana 
Published: May 2019

ZusammenfassungDie Reinduktion bzw. Rechallenge zielgerichteter Therapie bei Patienten mit BRAFV600‐mutierten Melanomen gewinnt zunehmend an Bedeutung. Die erneute Gabe von zielgerichteter Therapie erfolgt nach einer Medikamentenpause bei Nebenwirkungen, nach Bestrahlung oder Operation, nach Tumorprogress unter zwischengeschalteter Immun‐ oder Chemotherapie oder nach erneutem Progress ohne zwischengeschaltete Therapie. Bisher sind nur wenige Daten zu den Ergebnissen einer Rechallenge publiziert. Diese sind in der folgenden Arbeit präsentiert.Alle Arbeiten mit einer Gesamtpatientenzahl von 238 Patienten konnten zeigen, dass auch bei Patienten, die zuvor unter zielgerichteter Therapie einen Progress erlitten hatten, ein erneutes Ansprechen nach Wiedereinleitung möglich ist. Dieses variiert von stabiler Erkrankung, über partielles Ansprechen bis hin zu einzelnen Fällen mit kompletter Remission. Die Daten zeigen Ansprechraten auf eine Rechallenge von 47 %, wobei eine Krankheitskontrolle bei 67 % der Patienten erreicht werden konnte. Das mittlere progressionsfreie Überleben lag bei 6,4 Monaten. Das Ansprechen fiel allerdings kürzer aus als bei der erstmaligen zielgerichteten Therapie (mittleres progressionsfreies Überleben 9,2 Monate). Die Reinduktion zielgerichteter Therapie bietet somit eine weitere Option in der Behandlung bereits ausgiebig behandelter Krankheitszustände. Es bleibt zu klären, ob die Art der zwischengeschalteten Therapie einen Einfluss auf das erneute Ansprechen hat.
Trichophyton mentagrophytes – ein neuer Genotyp des zoophilen Dermatophyten verursacht sexuell übertragbare Infektionen
Authors: Kupsch Christiane , Czaika Viktor‐Alexander , Deutsch Cornelia , Gräser Yvonne 
Published: May 2019

ZusammenfassungHintergrundEin erst kürzlich in zwei Studien beschriebener neuer Genotyp des zoophilen Dermatophyten Trichophyton (T.) mentagrophytes wurde von drei Patienten mit Südostasienaufenthalt und von einem Patienten nach dem Aufenthalt in Ägypten isoliert. Im Gegensatz zu diesen Publikationen haben wir hier eine Anzahl von Fällen in der Dimension eines Epidemieausbruchs beobachtet.Patienten und MethodikAn der Charité – Universitätsmedizin Berlin wurden zwischen Januar 2016 und Juli 2017 43 Patienten beobachtet, die überwiegend an hoch entzündlichen, schmerzhaften und hartnäckigen Infektionen der Pubogenitalregion litten. Die mykologische Untersuchung erfolgte mittels Pilzkultur und Sequenzierung der ITS‐Region (Internal Transcribed Spacer) der ribosomalen DNA. Drei weitere genomische Regionen wurden stichprobenartig sequenziert.ErgebnisseIn 37 der Fälle wurde der neue Genotyp der Spezies T. mentagrophytes (hier T. mentagrophytes VII genannt) als Verursacher isoliert. Die Sequenzierungen ergaben identische Sequenzen für alle Isolate. Die meisten der infizierten Patienten hatten keine Reiseanamnese, nur zwei Patienten berichteten von Tierkontakt.SchlussfolgerungenDer neue Genotyp lässt sich phylogenetisch in vier verschiedenen DNA‐Markern der zoophilen Spezies T. mentagrophytes zuordnen. Während die Übertragung von zoophilen Dermatophyten von Mensch zu Mensch in der Regel selten ist, erfolgt die Übertragung hier scheinbar sehr effektiv über sexuellen Kontakt.
Multiple papillary fibroelastomas attached to left ventricular side and aortic side of the aortic valve: A report of new case and literature review
Authors: Tsugu Toshimitsu , Nagatomo Yuji , Endo Jin , Kawakami Takashi , Murata Mitsushige , Yamazaki Masataka , Shimizu Hideyuki , Fukuda Keiichi , Mitamura Hideo , Lancellotti Patrizio 
Published: May 2019

AbstractThe aortic valve (AV) is the most commonly affected site in multiple papillary fibroelastomas, but the frequency of embolism caused by the attachment side of the AV has not been elucidated. According to the review of the previous literature, 16 cases have been found attached to the AV. Of these, 6 of these have been found to be attached on the aortic side and 4 on the left ventricular side, 1 was bilateral, and 5 cases were unknown. Of the cases found on the aortic side, embolism occurred in 3 of them, and of the left ventricular side cases, embolism occurred in 2 of them. The frequency of embolism is equivalent even if papillary fibroelastoma attached to either side of the AV.
Googling the requester: Identity‐questing and discrimination in public service provision
Authors: Michener Gregory , Velasco Rafael B. , Contreras Evelyn , Rodrigues Karina F. 
Published: May 2019

AbstractInnovating upon previous field experiments and theories of identity‐based discrimination, we test whether public officials are using searches (“identity‐questing”) to profile citizens and acting on latent biases. Pairs of “institutional” and “noninstitutional” requesters send lower and moderate burden freedom of information (FOI) requests—providing no identity cues apart from undistinctive names, e‐mails, and ID numbers—to nearly 700 of Brazil's largest municipalities. Results show institutional requesters receive one‐fifth more responses than noninstitutional comparators. For moderate versus lower burden requests, noninstitutional requesters are 11% less likely to receive a compliant response than their institutional comparators. The only plausible explanation for these results is identity‐questing, a phenomenon that has far‐reaching policy implications. Most of the world's FOI laws, for example, contain vague ID obligations, which translate incoherently from laws to regulation and practice. Results enjoin public service providers to protect the identities of citizens by default or upon request.
Inadvertently high dialysate magnesium causing weakness and nausea in hemodialysis patients
Authors: Chakurkar Vipul V. , Gade Pritam S. , Godbole Anil V. , Wadia Farrokh F. , Lobo Valentine A. 
Published: May 2019

AbstractAs maintenance hemodialysis patients are exposed to large quantities of dialysis water, any contamination of it might be reflected in plasma levels. We present a series of cases due to such a contamination. Six maintenance hemodialysis patients dialyzing at the same peripheral hemodialysis facility presented to us over a short period of time with symptoms mimicking inadequate dialysis. Their blood urea and creatinine levels were not very high, but all the patients had hypermagnesemia [serum Mg levels = 1.8 (±0.3) mmol/L]. Except for one patient who had cardiac arrest at presentation, all patients improved after undergoing hemodialysis at our center [serum Mg at discharge = 0.86 (±0.01) mmol/L]. The origin of hypermagnesemia was traced to dialysis water contamination with magnesium due to inadequate maintenance of the water treatment system. Corrective measures improved the quality of water, and no further cases were reported from that center. Proper maintenance and periodic checks of the quality of water are central to the outcomes of maintenance hemodialysis patients.
Using patient‐reported outcomes to understand the effectiveness of guideline‐concordant care for post‐traumatic stress disorder in clinical practice
Authors: Shiner Brian , Gui Jiang , Leonard Westgate Christine , Schnurr Paula P. , Watts Bradley V. , Cornelius Sarah L. , Maguen Shira 
Published: May 2019

AbstractRationaleIdentifying predictors of improvement amongst patients receiving routine treatment for post‐traumatic stress disorder (PTSD) could provide information about factors that influence the clinical effectiveness of guideline‐concordant care. This study builds on prior work by accounting for delivery of specific evidence‐based treatments (EBTs) for PTSD while identifying potential predictors of clinical improvement using patient‐reported outcomes measurement.MethodOur sample consisted of 2 643 US Department of Veterans Affairs (VA) outpatients who initiated treatment for PTSD between 2008 and 2013 and received at least four PTSD checklist (PCL) measurements over 12 weeks. We obtained PCL data as well as demographic, diagnostic, and health services use information from the VA corporate data warehouse. We used latent trajectory analysis to identify classes of patients based on PCL scores, then determined demographic, diagnostic, and treatment predictors of membership in each class.ResultsPatients who met our PCL‐based inclusion criteria were far more likely than those who did not receive EBTs. We identified two latent trajectories of PTSD symptoms. Patients in the substantial improvement group (25.9%) had a mean decrease in PCL score of 16.24, whereas patients in the modest improvement group improved by a mean of 8.09 points. However, there were few differences between the groups, and our model to predict group membership was only slightly better than chance (area under the curve [AUC] = 0.55). Of the 64 covariates we tested, the only robust individual predictor of improvement was gender, with men having lower odds of being in the substantial improvement group compared with women (odds ratio [OR] 0.76; 95% confidence interval [CI] 0.58‐0.96).ConclusionVA patients with PTSD can realize significant improvement in routine clinical practice. Although available medical records‐based variables were generally insufficient to predict improvement trajectory, this study did indicate that men have lower odds of substantial improvement than women.
Drivers of growth for Atlantic cod (Gadus morhua L.) in Icelandic waters – A Bayesian approach to determine spatiotemporal variation and its causes
Authors: Frater Paul N. , Hrafnkelsson Birgir , Elvarsson Bjarki Th. , Stefansson Gunnar 
Published: May 2019

AbstractThis study assesses spatiotemporal and sex‐specific growth of Atlantic cod Gadus morhua in Icelandic waters. We use a Bayesian approach which lends itself to fitting and comparing nested models such as these. We then compare fitted parameters of these models to potential explanatory variables using a redundancy analysis (RDA) to look for drivers of growth in G. morhua. Results indicate that models that incorporate differences in growth among time, space and sex are the best‐fitting models according to deviance information criterion (DIC). Results from RDA indicate that capelin Mallotus villosus recruitment and biomass is highly correlated with deviations in the von Bertalannfy growth parameter k and that
L∞ is correlated with G. morhua landings in the model that uses year to account for time‐varying growth and estimated G. morhua recruitment in the model that uses cohort to account for time‐varying growth.
Anti‐PirA‐like toxin immunoglobulin (IgY) in feeds passively immunizes shrimp against acute hepatopancreatic necrosis disease
Authors: Nakamura Rika , Pedrosa‐Gerasmio Ivane R. , Alenton Rod Russel R. , Nozaki Reiko , Kondo Hidehiro , Hirono Ikuo 
Published: May 2019

AbstractAcute hepatopancreatic necrosis disease (AHPND), caused by a toxin‐producing Vibrio parahaemolyticus strain, has become a serious threat to shrimp aquaculture. The need to regulate antibiotic use prompted the development of alternative ways to treat infections in aquaculture including the use of chicken egg yolk immunoglobulin (IgY) for passive immunization. This study evaluated the protective effect of IgY against AHPND infection in Litopenaeus vannamei (Boone). IgY was isolated from eggs laid by hens immunized with recombinant PirA‐like (rPirA) and PirB‐like (rPirB) toxins. Whole‐egg powders having IgY specific to rPirA (anti‐PirA‐IgY) and rPirB (anti‐PirB‐IgY) and IgY from non‐immunized hen (control‐IgY) were mixed with basal diets at 20% concentrations and used to prefeed shrimp 3 days before the bacterial challenge test. Survival rates of the challenged shrimp fed the anti‐PirA‐IgY, anti‐PirB‐IgY and control‐IgY diets were 86%, 14% and 0%, respectively. Only the feed containing anti‐PirA‐IgY protected shrimp against AHPND. Increasing the concentration of rPirA antigen to immunize hens and lowering the amount of egg powder in feeds to 10% consistently showed higher survival rates in shrimp fed with anti‐PirA‐IgY (87%) compared with the control (12%). These results confirm that addition of anti‐PirA‐IgY in feeds could be an effective prophylactic method against AHPND infection in shrimp.
Moderate‐to‐Vigorous Physical Activity Is Associated With Higher Muscle Oxidative Capacity in Older Adults
Authors: Adelnia Fatemeh , Urbanek Jacek , Osawa Yusuke , Shardell Michelle , Brennan Nicholas A. , Fishbein Kenneth W. , Spencer Richard G. , Simonsick Eleanor M. , Schrack Jennifer A. , Ferrucci Luigi 
Published: May 2019

BACKGROUNDAge‐related decline in muscle oxidative capacity reduces muscle function and physical performance, leading to disability and frailty. Whether age‐related decline in oxidative capacity is modified by exercise and other lifestyle practices is unclear. Therefore, we tested the hypothesis that physical activity is associated with better oxidative capacity, independent of age.DESIGNCross‐sectional study performed in the Baltimore Longitudinal Study of Aging, conducted by the Intramural Research Program (IRP) of the National Institute on Aging (NIA).SETTINGNIA IRP Clinical Research Unit, Baltimore, MD.PARTICIPANTSParticipants included 384 adults (54.7% women), aged 22 to 92 years, seen between 2013 and 2017.MEASUREMENTSMuscle oxidative capacity was measured in vivo using phosphorous magnetic resonance spectroscopy. We determined the postexercise time constant (τPCr; in seconds) for phosphocreatine (PCr) recovery, with lower values of τPCr, (ie, more rapid recovery of PCr levels after exercise) reflecting greater oxidative capacity. Time spent in moderate‐to‐vigorous physical activity (MVPA) was assessed using wearable accelerometers that participants wore 5.9 ± 0.9 consecutive days in the free‐living environment.RESULTSIn linear regression models, higher τPCr was associated with older age (standardized β = .39; P < .001) after adjusting for sex, race, height, and weight. After including MVPA as an independent variable, the standardized regression coefficient of age decreased by 40%, but remained associated with τPCr (βage = .22; P < .001) and had a smaller standardized regression coefficient than MVPA (βMVPA = −.33; P < .001). After adjusting for health status, education, and smoking history, the standardized regression coefficient for age decreased 12% (βage = .20; P = .003), while the standardized coefficient for MVPA decreased only 3% (βMVPA = −.32; P < .001).CONCLUSIONStudy findings suggest that MVPA is strongly associated with muscle oxidative capacity, independent of age, providing mechanistic insights into the health benefits of exercise in older age. J Am Geriatr Soc 67:1695–1699, 2019