bluuebunny/crossref_metadata_2025_split huggingface dataset:
Propagation Directions of Ocean Surface Waves inside Tropical Cyclones
Authors: Hwang Paul A. , Walsh Edward J. 
Published: May 2018

AbstractSurface wave propagation inside tropical cyclones (TCs) is complicated and multiple wave systems are frequently observed. The directional wave spectra acquired by hurricane hunters are analyzed to quantify its azimuthal and radial variations. Referenced to the hurricane heading, the dominate feature in the front half of the TC coverage area is single wave systems propagating toward left and left-front. Multiple wave systems are generally observed in the back and right quarters outside the radius of maximum wind (RMW). The directional differences and locations of occurrences of multisystem spectra are Gaussian distributed. The directional differences of the secondary and tertiary wave systems from the primary system are centered around 60°–70°. The minor systems are more likely on the left-hand side of the primary system than on the right-hand side by a 3-to-1 ratio. The most likely azimuthal location of multisystem spectra is about 210° counterclockwise from the heading. In the right-front quarter, waves propagate into the advancing wind field and experience extended air–sea exchanges to grow higher and longer; in the left-rear quarter, they propagate away from the advancing wind field and are more likely younger seas. The radial variation of wave propagation is relatively minor except inside the RMW. A model describing the dominant wave propagation direction is presented. The regression statistics between modeled and measured wave directions show consistent agreement in 9 of the 11 datasets available for investigation. Causes for the significantly different statistics of the two remaining datasets include proximity to coast (a landfalling case) and rapid change in the hurricane translation speed or direction.
Airway Anomalies in Patients With 22q11.2 Deletion Syndrome: A 5-Year Review
Authors: Jones Joel W. , Tracy Meghan , Perryman Mollie , Arganbright Jill M. 
Published: May 2018

Objectives: To characterize the frequency of airway anomalies in patients with 22q11.2 deletion syndrome (22q11DS). Methods: Retrospective review of patients with 22q11DS who had undergone microlaryngoscopy/bronchoscopy (MLB) for aerodigestive symptoms at a tertiary care children’s hospital from 2011 to 2016. Results: Thirty patients underwent an MLB due to the following indications: aspiration (11), stridor (10), chronic respiratory failure due to ventilator dependence (8), and difficult intubation (1). Median age at MLB was 6.5 months (range, 0.25-32 months). Forty airway anomalies were identified in 20 (66%) patients. Laryngomalacia (10), tracheomalacia (8), and bronchomalcia (8) were the most common intraoperative findings, followed by laryngeal cleft (5), anterior glottic web (5), subglottic stenosis (3), and subglottic cysts (1). Synchronous airway anomalies were common and identified in 11 (55%) of the patients who had identified anomalies on MLB. Nineteen of the 20 patients required operative intervention due to the anomalies identified. Conclusions: Structural airway abnormalities are common in children with 22q11DS undergoing MLB, and synchronous anomalies can frequently exist. Providers caring for children with 22q11DS should be vigilant about airway evaluation when aerodigestive symptoms are present.
Opinions on the use of technology to improve tablet taking in >65-year-old patients on cardiovascular medications
Authors: Holender Anita , Sutton Stephen , De Simoni Anna 
Published: May 2018

Objective This study was performed to evaluate the perceptions of the use of technology to improve cardiovascular medicine taking among patients aged >65 years. Methods This qualitative study used focus groups with people aged >65 years taking cardiovascular medications from two East London community centres. Thematic analysis was informed by the Perceptions and Practicalities Approach framework. Results Participants welcomed technologies they considered familiar, accessible, and easy to use. They valued the opportunity to receive alerts to help with forgetting and monitoring their treatment. More advanced technologies such as ingestible sensor systems were considered helpful for elderly people with significant cognitive impairments still living in the community because of improved monitoring by caregivers and clinicians and prolonging independence. Although generally adapting to the increase in technology in everyday life, participants raised a number of concerns that included potential reduction in face-to-face communication, data security, becoming dependent on technology, and worrying about the consequences of technological failure. Conclusions Participants raised a number of concerns and practical barriers that would need to be addressed for technologies to be accepted and adopted in this patient group.
Quantifying Patient-Reported Disability and Health While Waiting for Bunion Surgery
Authors: Sutherland Jason M. , Wing Kevin , Penner Murray , Younger Alastair , Liu Guiping , Veljkovic Andrea , Crump Trafford 
Published: May 2018

Background: Many patients with hallux valgus progress to experiencing pain and loss of function that requires corrective surgery when nonoperative treatments fail. The primary goal of this study was to measure changes in participants’ health while patients waited for their operative correction. Methods: Patients were prospectively recruited to complete a number of patient-reported outcome measures preoperatively. Baseline data collection was initiated in October 2014, and participants’ second surveys were returned by August 2017. The setting of the study was Vancouver, Canada. There were 80 participants in the study. The participation rate among eligible patients was 52.7%. Results: The average wait time for surgery exceeded 8 months, with a mean wait of 35.7 weeks. Baseline pain among participants was high. Only in the domain of foot- and ankle-related quality of life was the duration of wait time associated with participants’ change in health. The other 4 domains of foot function remained stable over the preoperative period. Conclusion: Preoperative health in this study was consistent with other research showing high pain and compromised foot function among patients failing nonoperative therapies for treatment of hallux valgus. This study found high pain and compromised foot function among patients waiting for hallux valgus surgery but only minor relationships between participants’ duration of wait time for operative correction of the first metatarsophalangeal joint and changes in patient-reported outcome scores. Level of Evidence: Level III, comparative study.
Chronic and Subacute Meningitis: Differentiating Neoplastic From Non-Neoplastic Etiologies
Authors: Marrodan Mariano , Bensi Catalina , Alessandro Lucas , Muggeri Alejandro D. , Farez Mauricio F. 
Published: May 2018

Background and Purpose: Although incidence rates vary, infectious, autoimmune, and neoplastic diseases can all cause chronic and subacute meningitis (CSM). We report a Latin-American, single center, CSM case series, analyzing the main clinical characteristics as well as ancillary diagnostic methods differentiating neoplastic from non-neoplastic etiologies. Methods: Retrospective review of CSM cases from a single center in Buenos Aires, Argentina. Results: Seventy patients with CSM diagnosis were identified, 49 with neoplastic and 21 with non-neoplastic meningitis. A history of previous cancer was significantly higher in neoplastic cases, whereas prevalence of autoimmune disease and fever was more common in non-neoplastic meningitis. C-reactive protein values were higher in non-neoplastic CSM, as was pleocytosis in cerebrospinal fluid analysis. The most frequent etiologies were breast and lung cancer for neoplastic meningitis cases; and idiopathic, tuberculous, and fungal infection for non-neoplastic cases. Conclusions: Chronic and subacute meningitis diagnosis is challenging in daily neurological practice. The results we report contribute information from Latin America regarding etiologies of CSM, which can be identified after a comprehensive evaluation in a majority of cases.
Model Order Reduction for convection dominated problems
Authors: Bansal Harshit , Iapichino Laura , Rave Stephan , Schilders Wil , van de Wouw Nathan 
Published: May 2018

Model Order Reduction (MOR) of systems of non-linear(parameterized) Hyperbolic Partial Differential Equations (PDEs) is still an uncharted territory in the scientific community. Moving discontinuities are representative features of this class of problems and pose a major hindrance to obtain effective reduced-order model representations, since typically bases with high spatial frequency are needed to accurately capture these moving discontinuities. We will discuss a MOR framework to efficiently capture the travelling dynamics of such systems. The motivation of this work is to enable the usage of multi-phase hydraulic models, such as the Drift Flux Model (DFM) [2] in developing drilling automation strategies for real-time down-hole pressure management.
The DFM is a system of multiscale non-linear PDEs, whose convective subset is conditionally hyperbolic. Convection dominated problems, such as the DFM, admit solutions, which possess a diagonal structure in space-time diagram and high solution variability. As a first step, we apply standard MOR approaches [4] to obtain a reduced-order representation of the DFM for a representative multi-phase shock tube test case. We capture the dynamics in an essentially non-oscillatory manner but we obtain a small dimensionality reduction. Since the dimension of the reduced model is still too large, we develop new techniques for deriving more efficient alternative reduced-order models for this class of problems.
We invoke the idea of the method of freezing [1] and combine it with non-linear reduced basis approximations [3] to develop an efficient reduced-order model representation, which we demonstrate for several benchmark problems. These benchmark problems embody the challenges faced in the reduced-order representation of the DFM. However, the existing MOR framework [3] lacks consideration of boundary conditions and multiple fronts. The main novelty of this work is in investigating the performance of combined approach of Method of Freezing and reduced basis approximations in dealing with merging (discontinuous) wave-fronts. Finally, we present numerical experiments and discuss the efficacy of above mentioned approach in terms of computational speed up and computational accuracy compared with standard numerical techniques.
Principal component analysis and optimal weighted least-squares method for training tree tensor networks
Authors: Haberstich Cécile , Nouy Anthony , Perrin Guillaume 
Published: May 2018

One of the most challenging tasks in computational science is the approximation of high-dimensional functions. Most of the time, only a few information on the functions is available, and approximating high-dimensional functions requires exploiting low-dimensional structures of these functions.
In this work, the approximation of a function u is built using point evaluations of the function, where these evaluations are selected adaptively. Such problems are encountered when the function represents the output of a black-box computer code, a system or a physical experiment for a given value of a set of input variables. This algorithm relies on an extension of principal components analysis (PCA) to multivariate functions in order to estimate the tensors
$v_{\alpha}$
.
In practice, the PCA is realized on sample-based projections of the function u, using interpolation or least-squares regression.
Least-squares regression can provide a stable projection but it usually requires a high number of evaluations of u, which is not affordable when one evaluation is very costly. In [1] the authors proposed an optimal weighted least-squares method, with a choice of weights and samples that garantee an approximation error of the order of the best approximation error using a minimal number of samples.
We here present an extension of this methodology for the approximation in tree-based format, where optimal weighted least-squares method is used for the projection onto tensor product spaces. This approach will be compared with a strategy using standard least-squares method or interpolation (as proposed in [2]).
A Reduced Basis Technique for Long-Time Unsteady Turbulent Flows
Authors: Taddei Tommaso 
Published: May 2018

For turbulent flows, estimation of the entire solution trajectory through a low-dimensional Reduced Order Model might be unfeasible due to the slow convergence of the Kolmogorov N-width, and due to the sensitivity of the dynamical system to perturbations.
Nevertheless, it might still be possible to estimate the time-averaged solution and associated quantities of interest.
In this poster, we propose a Reduced-Basis technique for the estimation of long-time-averaged solutions of parametrized turbulent flows. The key elements of our approach are (i) a Greedy technique for the construction of a low-dimensional reduced space, and (ii) a constrained POD-Galerkin formulation of the reduced solution.
The Greedy technique relies on a novel residual indicator for the error in the long-time-averaged solution.
We present a number of numerical examples to illustrate our approach, and to demonstrate the effectivity of the error indicator.
Endocarditis infecciosa por Aggregatibacter actinomicetemcomitans en un paciente con síndrome de inmunodeficiencia adquirida.
Authors: Gomez Colussi Andrea Florencia , Crespo Alejandro Gustavo , Mendosa Maria Alejandra , Nagel Alicia , Gutiérrez Cesar Ernesto , Argarañá Maria Fernanda 
Published: May 2018

Aggregatibacter actinomycetemcomitans es una bacteria Gram negativa que se encuentra formando parte de la microbiota normal de la cavidad oral en el hombre. Cuando existe un estado de inmunidad deprimida en el huésped, este microorganismo puede ocasionar cuadros infecciosos, entre ellos endocarditis. La endocarditis infecciosa (EI) es una enfermedad poco frecuente y grave, en particular si el agente causal es un microorganismo fastidioso, cuya identificación puede retrasarse. El diagnóstico precoz de la enfermedad, la identificación temprana de los pacientes con más riesgo, así como un abordaje multidisciplinar pueden ser estrategias válidas para mejorar el pronóstico de estos enfermos. Reportamos el primer caso en Santa Fe de EI en paciente con inmunodeficiencia adquirida (VIH), sin antecedentes de cardiopatía. El tratamiento con ceftriaxona resultó eficiente y el paciente no requirió intervención quirúrgica.
Prevalencia y factores epidemiológicos de infecciones del tracto urinario causadas por Escherichia coli productora de betalactamasa de espectro extendido en el Sanatorio Adventista del Plata
Authors: Martinez Maria Valeria 
Published: May 2018

La hidrólisis de antibióticos beta-lactámicos por betalactamasas es uno de los mecanismos de resistencia mas frecuentemente encontrados en enterobacterias. En el presente trabajo se estudió un total de 1.167 urocultivos que ingresaron en el laboratorio durante cuatro meses, de los cuales el 24,0% fueron positivos, 68,6% se identificaron como Escherichia coli y 8,9% fueron cepas productoras de betalactamasa de espectro extendido (BLEE), de las cuales todas fueron tipo CTX-M grupos 1,2 y 9. El 83,2% correspondieron a mujeres (X2=19,286; p=0,000), el 85,9% correspondió a infecciones de la comunidad (X2=1,258; p= 0,262) en un rango etario de 1-94 años. La mayoría de los aislamientos fueron resistentes a ciprofloxacina (86,7%) y trimetoprima/sulfametoxazol (80,0%).Aunque están muy discutidas las medidas de control de diseminación de E.coli productora de BLEE, no se puede negar la necesidad de implementar un uso correcto y responsable de los antibióticos para evitar la expansión de cepas resistentes.
Linfadenitis por Mycobacterium genavense
Authors: Vargas Marcela Fabiana , Longoni Silvia , Guerra Alejandra Cristina 
Published: May 2018

La micobacteriosis atípica es una enfermedad granulomatosa crónica o aguda causada por micobacterias no tuberculosas que incluyen a un grupo de bacilos ácido alcohol resistentes pertenecientes al género Mycobacterium sp. que afectan principalmente a pacientes con déficit del sistema inmunitario celular. Mycobacterium genavense es una especie relativamente nueva de micobacterias no tuberculosas reportada como causa de infecciones diseminadas oportunista en pacientes con severa inmunodeficiencia celular en el contexto del síndrome de inmunodeficiencia adquirida en la infección por el Virus de Inmunodeficiencia Humana (HIV/SIDA) y trasplantados de órganos sólidos bajo tratamiento inmunosupresor agresivo. Se presenta un caso de diagnóstico tardío de linfadenitis ganglionar diseminada por Mycobacterium genavense de dos años de evolución como enfermedad marcadora de HIV/SIDA. En el análisis microbiológico la ausencia de crecimiento en los medios de cultivos sólidos habituales para micobacterias, y el crecimiento solo en medio liquido, requirió el análisis de técnicas moleculares con el método de polimorfismo de los fragmentos de restricción (PCR-RFLP) que permitió identificar al microorganismo causante de la enfermedad.
Malignus kevert Müller-cső-eredetű tumor komplex kezelése
Authors: Kalincsák Judit , Gőcze Péter , Bódis József , Kovács Krisztina , Stefanovits Ágnes , Bohonyi Noémi , Péntek Sándor , Papp Szilárd 
Published: May 2018

Abstract: Introduction and aim: The aim of our study was to evaluate the prognostic factors and treatment options of a very rare and highly aggressive type of uterine neoplasms, the malignant mixed Müllerian tumor, known as carcinosarcoma. Method: Between 2009 and 2017, 29 patients were treated with malignant mixed Müllerian tumor. At stage I, surgery and postoperative radiotherapy were performed. At stages II−IV, trimodal treatment (surgery, chemotherapy and radiotherapy) was administered. Results: The average age of patients was 68.51 (49–90) years, mean body mass index was 30.22 (20.90–37.22). We have experienced recurrence of disease after complete resection in 6 cases (4 of 6 patients did not accept radiation therapy). Local recurrence has occurred after an average 15.52 (6−36) months, distant metastasis with an average 19.2 (8–32) months. Overall survival was 11.92 (1–75) months. Six patients are free of tumours at the moment. Conclusions: As overall survival has not increased in recent decades by using combined chemotherapy, there is no congruent consensus associated with the optimal treatment. The standard surgical treatment is total abdominal hysterectomy with bilateral oophorectomy, although due to high rates of recurrence and metastases, the necessity of lymphadenectomy and postoperative treatment is in the focus of recent studies. Though postoperative irradiation improves local control, the beneficial effect on overall survival is still not proven. Adjuvant chemotherapy decreases the rate of both pelvic and extrapelvic recurrence at the same time, although there is no recommendation for the optimal chemoterapeutic agent. Multimodal therapy should lead to better outcomes. Recently there are many ongoing studies with biologic and target therapies to improve efficiency, however, the relevant results will be disclosed in many years only, due to the small number of patients. Orv Hetil. 2018; 159(19): 741–7747.
A hosszú távú protonpumpagátló kezelés következményei felnőtteken
Authors: Igaz Iván , Simonyi Gábor , Balogh Sándor , Szathmári Miklós 
Published: May 2018

Abstract: In the last few decades, proton-pump inhibitors have become the mainstay of the treatment of acid-related disorders. Despite their efficacy, these drugs are not without risks. Recently several articles have been published on their long-term adverse effects. Among these adverse effects, the higher risk of bone fractures, the vitamin B12 and magnesium deficiencies and the higher risk of Clostridium difficile infection may be relevant. As these drugs are prescribed more and more frequently all over the world, the knowledge of the long-term adverse effects is very important not only for the specialists but for the general practitioners as well. In this review, the authors discuss the recent findings in this field, emphasising that the long-term use of these drugs must be based on an adequate and strong indication. Orv Hetil. 2018; 159(19): 735–740.
К вопросу о философии и практике менеджмента в сфере образования
Authors: Гопко Владимир Васильевич 
Published: May 2018

<p>В течение последних двух десятилетий менеджмент в вузах страны стал одной из широко преподаваемых дисциплин. Возникает вопрос о возможности применения некоторых принципов менеджмента в условиях российской действительности. Несмотря на популярность и некоторую модность самого слова «менеджмент», последний, с точки зрения автора, не стал научной основой управления и не приобрел национальной специфики, которую можно было характеризовать как позитивную. В статье предпринимается попытка рассмотреть некоторые аспекты данного вопроса применительно к системе образования.</p>
Outcome of UVA-Riboflavin collagen cross-linking of cornea in patients with keratoconus
Authors: KARADAĞ Ayşe Sevgi , BİLGİN Burak , ÖZDEMİR Nusret 
Published: May 2018

Purpose: In this study, we aimed to show changes of central corneal thickness and effects of treatment on visual acuity after corneal collagen cross-linking in keratoconus patients.Materials and Methods: 26 eyes of 51 patients with keratoconus who undergone corneal collagen cross-linking were included in to the study. Central corneal thickness measurements and best corrected visual acuity were recorded before and after 1st and 6th month of corneal collagen cross-linking operation.Results: Mean central corneal thickness measurements were recorded as; 435,43±44,35 μm, 376,68±66,55 μm and 392,62±64,21 μm before and after 1st and 6th month of corneal collagen cross-linking, respectively. There was a statistically significant difference between pre-op and postop 1st month, pre-op and postop 6th month and post-op 1st month and post-op 6th month central corneal thickness measurements. Also, there was a statistically significant increase in best corrected visual acuity after the operation.Conclusion: There was a statistically significant difference between pre-op, post-op 1st month and postop 6th month central corneal thickness and best corrected visual acuity measurements.
Drug induced gingival enlargement: dentist’s dilemma
Authors: Kulkarni Arati V , Kini Raghavendra , Rao Prasanna Kumar , Bhandarkar Gowri P , Kashyap Roopashri Rajesh 
Published: May 2018

Gingival enlargement is a routine finding in regular dental practice. Though it has many etiological factors, enlargement due to drugs which are administered to treat the systemic problems is of major concern which needs attention. Drug-induced gingival overgrowth is frequently associated with anti hypertensives, anticonvulsants and immunosuppressants. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. It gradually becomes a source of pain and the condition often leads to disfiguration. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. It would seem ideal to identify and explore possible risk factors and relate them with the treatment plan. Here, we present a case of a 33 year old female patient on nifedipine since five years with drug induced gingival enlargement and its management