bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring Medical Foster Care as a Placement Option for Children With Medical Complexity
Authors: Seltzer Rebecca R. , Raisanen Jessica C. , Williams Erin P. , Da Silva Trisha , Donohue Pamela K. , Boss Renee D. 
Published: September 2019

BACKGROUND:
Medical foster care (MFC) offers a family-home setting for children with medical complexity (CMC) who cannot be cared for by their parents. We explored MFC as a placement option for CMC via in-depth interviews with the individuals providing and monitoring care.

METHODS:
In collaboration with an MFC agency, we recruited care team members for 15 CMC. Semistructured interviews were audiotaped and transcribed. Descriptive analyses were performed on care team composition and roles, the placement process, and child medical, placement, and quality of life (QoL) characteristics. Foster parents completed child QoL questionnaires. Conventional content analysis was applied to participant suggestions for MFC improvements.

RESULTS:
Fifty-eight interviews were conducted; a median of 4 care team members interviewed per child. An extensive network of individuals and systems are involved in providing care. Each child received care from multiple subspecialists (median = 5). Most children were technology dependent (87%), developmentally delayed (87%), and entered MFC from the hospital (73%) because of medical neglect (86%). Nearly half were in care for &gt;2 years. Changes in placement and/or care team were common. QoL scoring showed impairments in multiple domains, whereas respondent interviews described positive aspects of QoL. Participants provided suggestions to improve care within MFC.

CONCLUSIONS:
MFC is a promising placement option for CMC. Because many CMC are entering MFC directly from the hospital and require ongoing care from pediatric subspecialists, pediatricians should be familiar with MFC, the placement process, and the various systems and individuals involved. Pediatricians can play important roles in ensuring that children in MFC receive coordinated and high-quality care.
Documentation of Tobacco, Alcohol, and Drug Screening in Hospitalized Adolescents
Authors: Riese Alison , Tarr Elizabeth , Baird Janette , Alverson Brian 
Published: September 2019

OBJECTIVES:
To examine the frequency of documented screening for tobacco, alcohol, and drug use in hospitalized adolescents on the pediatric hospitalist service.

PATIENTS AND METHODS:
This was a retrospective chart review of adolescents aged 14 to 17 years hospitalized at a large urban academic children’s hospital in the Northeast from 2013 to 2015. Only patients admitted directly to the hospitalist service and only the first admission (if multiple occurred) were included. Patients presenting for psychiatric illness, ingestions, or impaired neurologic functioning were excluded. Admission history and physical (H&P) notes were reviewed to identify documented screening for tobacco, alcohol, and drug use. χ2 tests and 95% confidence intervals (CIs) were used to compare screenings for each substance and assess for associations of patient and encounter characteristics.

RESULTS:
A total of 443 charts met criteria for inclusion. The majority of adolescents were girls (n = 286; 64.6%), and mean age was 15.6 years (SD: 1.1). The H&P notes included notation of screening for tobacco use in 75.4% (95% CI: 71.1%–79.3%), alcohol use in 56.4% (95% CI: 51.7%–61.1%), and drug use in 37.9% (95% CI: 33.4%–42.6%) of charts. Girls were 1.4 times more likely to have of documented screening for alcohol use than boys. The admission diagnosis category was significantly associated with documentation of alcohol screening. Tobacco and drug screening frequency did not differ on the basis of sex, age, or diagnosis category.

CONCLUSIONS:
Documentation of substance use screening was not universal in admission H&P notes. These discrepancies suggest a need for improvements in screening protocols and documentation methods.
Partially Wireless Pulse Oximetry Reduces Loss of Signal Integrity due to Motion in Children
Authors: Petersen Pamela C. , Hanson Sheila , Yan Ke , Clarke William 
Published: September 2019

OBJECTIVES:Continuous pulse oximetry monitoring is routine in many pediatric inpatient units, generating hundreds of alarms per patient per day, up to 90% of which are false (nonactionable). We hypothesized that continuously monitoring pulse oximetry with a partially wireless monitor without physical connection to a wall unit (wireless pox) will decrease episodes of loss of signal integrity (LOSI) generated by motion artifact in healthy pediatric subjects completing age-appropriate activities compared with a traditional wall-connected pulse oximeter (control pox), thereby reducing false alarms.METHODS:Thirty-six healthy children, aged 1 to 17 years, were continuously monitored simultaneously with a wireless pox and a control pox while performing increasing levels of activity for 20 minutes. Continuous pulse oximetry data were recorded in 2 second intervals. Data were analyzed for LOSI. The Wilcoxon signed rank test was then used to compare the control pox to the wireless pox.RESULTS:The wireless pox had fewer mean number of alarms due to LOSI (control 7.86, wireless 4.17, P = .0031) and fewer mean episodes of LOSI not leading to alarms (control 9.94, wireless 6.92, P = .0006). The control pox had a longer percent time in alarm state related to LOSI in all age groups.CONCLUSIONS:This prospective observational study found that the wireless pox has decreased number and duration of events of LOSI compared with the control pox in healthy children. Implementation of partially wireless pulse oximetry in pediatric inpatient units may decrease episodes of LOSI and false alarms from motion artifact.
Educação, Estado e ideologia no Brasil: da colônia (1549) à República (1889) / Educación, Estado e ideología en Brasil: de la colonia (1549) a la República (1889)
Authors: De Souza Mériti , Carvalho de Carvalho Diana 
Published: September 2019

Resumo: O ensaio trata da relação entre o contexto social, econômico e político e a organização escolar no Brasil de 1549 a 1889. Destacamos mecanismos ideológicos que operaram no período analisado e suas relações com a construção da escolarização brasileira, buscando apontar o caminho histórico percorrido pelas diretrizes governamentais e as transformações no cenário educacional. Nos primórdios da implantação do sistema escolar circulavam ideologias vinculadas às elites, o que não exigia interferência do Estado para sua legitimação. A partir de meados do século XIX, momento em que essas ideologias não convergiam com seus interesses, observou-se a mudança de postura do Estado, no sentido de aumentar o controle sobre a circulação de ideologias no interior das escolas.

Resumen: El ensayo trata acerca de la relación entre el contexto social, económico y político, y la organización escolar en Brasil durante los años comprendidos entre 1549 y 1889. Destacamos mecanismos ideológicos que operaron en el período analizado y sus relaciones con la construcción de la escolarización brasileira. Se busca señalar el camino histórico recorrido por las directrices gubernamentales y las transfromaciones en el escenario educacional. En los inicios de la implantación del sistema escolar circulaban ideologías vinculadas a las élites, lo que no exigía interferencia del Estado para su legitimación. A partir de mediados del siglo XIX, momento que esas ideologías no convergían con sus intereses, se observó el cambio de postura del Estado, en el sentido de aumentar el control sobre la circulación de ideologías en el interior de las escuelas.
Possible protective effect of quercetin against oxidative stress in liver from metabolic syndrome rats
Authors: BİLGİNOĞLU Ayça 
Published: September 2019

AbstractBackground/Aims:Metabolic
syndrome (MS) is linked to type of type 2 diabetes mellitus associated with
high glucose level and insulin resistance. Thioredoxin-1 (TRX-1) is localized
in the cytoplasm and the mitochondria and controls cellular reactive oxygen
species. The purpose of this study is to examine the relation between MS and
oxidative stress, and effect of quercetin on oxidative stress via TRX-1 in
liver of MS rats. Methods: Male wistar rats (200-250g in weight) were used. They were divided three
groups. Control group, MS group receiving (935 mM sucrose in drinking water)
and quercetin treated (15 mg/kg/day, administered by gavage) MS group. Protein
level of TRX-1 was determined by Western blot.Results:Aspartate
transaminase (AST), alanine transaminase (ALT), lactate dehydrogenase (LDH),
levels increased in MS group as compared with the Con group. Total-antioxidant-status
(TAS), superoxide-dismutase (SOD), and glutathione-peroxidase (GSH-Px) levels
decreased in MS group when compared to Con group. Total-oxidant-status (TOS)
levels increased in MS group as compared with the Con group. Triglycerides, total-cholesterol
and LDL-cholesterol increased in MS group when compared with the Con group. TRX-1
level decreased in MS group and TRX-1 activity was lower in MS group than Con
group. Conclusions: Treatment
of quercetin decreased AST, ALT, LDH, and TOS levels while it increased GSH-Px,
SOD, and TAS levels. Also, lipid profile changed with quercetin. In conclusion,
treatment of quercetin significantly increased TRX-1 level and activity of
TRX-1 in MS group. These data suggest that elevated oxidative stress in liver
of MS may be reduced by quercetin.
Skin prick test results in patients with chronic allergic rhinitis: Housewives are risky occupational group for the development of allergic rhinitis due to house dust mites
Authors: OZDEMİR Tarkan , KASAPOGLU Benan , TURKKANİ Mustafa , OZDİLEKCAN Cigdem , EREL Fuat 
Published: September 2019

Background/Aims: Allergic Rhinitis (AR) is a common disorder that negatively effects the quality of life with symptoms due to the inflammation of nasal epithelium. Objective of this study is to determine the general demographical and clinical features of patients with AR, who had positive skin prick test (SPT) results. Methods: Patients diagnosed as AR with positive SPT results were analyzed. The allergens tested were: grasses, cereals+grasses , trees 1 (early flowering), trees 2 (late flowering), house-dust mites ( Dermatophagoides pteronyssinus (DP), Dermatophagoides farinae (DF), tyrophagus putrescentiae (TP), lepidoglyphus destructor (LD) and acarus siro (AS). Results: Of the total 202 patients, 145 female (with a mean age of 32.42 ±12.81 years) and 57 male (with a mean age of 28.44 ± 11.5 years) were included in the study. The most common allergens determined were; DF, DP, cereals+grasses and grasses. Tyrophagus significantly was more common in females (p:0.04). Nasal discharge, dyspnea, itching and weakness-tiredness were reported to be more common in females compared with males. DF, DP, TP and LD were statistically significantly more common in housewives (p&lt;0.05). Dyspnea, wheezing and itching were statistically significantly more common in housewives (p&lt;0.05).Conclusions: Housewives
are risky occupational group for the development of allergic rhinitis due to
house dust mites
The Effect of Follicular Fluid on the Proliferation and Osteoblastic Differentiation of Human Bone Marrow Mesenchymal Stem Cells
Authors: Soltani Atefeh , Abroun Saeid , Rezazadeh Valojerdi Mojtaba , Vahidianfar Bahareh , Hosseini Elahe Sadat 
Published: September 2019

Background and Aims: Bone marrow-derived mesenchymal stem cells (BM-MSCs) are a well-known source of multipotent adult stem cells. Despite using different methodologies of MSCs preparing for clinical applications, the top safest procedure to manipulate these cells, has not yet been determined. Recently, ex-vivo expansion of MSCs for their subsequent implantation, using some biological product, is suggested instead of fetal bovine serum (FBS). Previous studies have shown the effect of follicular fluid (FF) (a dynamic fluid in ovarian follicle) as an additive component in cell culture. Hence, this study aimed to decipher its role on the human BM-MSC proliferation.Materials and Methods: In this study, BM-MSCs at 3rd passage were cultivated in the presence of 20% FF (group I), 10% FF+ FBS 10% (group II) and FBS 20% as control group. The capacity of proliferation as calculating population doubling times and gene expression levels of stem cell factor, stromal cell-derived factor 1, and transforming growth factor beta were analyzed in osteogeneic media to examine the impacts of FF on osteogenesis of MSCs.Results: Our results corroborated an up-regulatory effect of FF on the proliferation of BM-MSCs by shorter population doubling times in the group II of treated cells and an increase in gene expression level of osteocalcin and transforming growth factor beta in the presence of higher concentrations of FF in cell culture FF 20% and 10%, respectively.Conclusions: FF is a potent mitogen for cell proliferation. FF may be an efficient substitution of FBS in ex-vivo cell culture, eliminating zoonotic infections and immunological reactions.
Genotyping of Mycobacterium Tuberculosis Isolated from Suspected Patients in Tehran in 2015-2017
Authors: Zaker Saeed , Bagherifard Hanie 
Published: September 2019

Background and Aims: Unlike many global efforts to eradicate tuberculosis caused by Mycobacterium, it remains as a life-threatening infection with a worldwide incidence of 1.5 million cases each year. However, due to the lack of information about Mycobacterium tuberculosis characterization, more studies are required to evaluate strain diversity and epidemiology of tuberculosis to improve the therapeutic approaches. This study aimed to genotype the Mycobacterium tuberculosis isolated from suspected patients in Tehran, Iran through 2015-2017.Materials and Methods: In the current study, 30 isolates (sputum, broncho-alveolar lavage and biopsy) were collected from different tuberculosis patients at Massoud Clinical Lab of Tehran from 2015 to 2017. To find the single nucleotide polymorphisms and mutated regions, polymerase chain reaction (PCR) was performed on all the isolates to amplify the katG and gyrA genes. Then, PCR products were sequenced and analyzed.Results: The majority of isolates were assigned to PGG2 (90%), followed by PGG3 (10%) but no isolate belonging to PGG1 was found.Conclusions: Our findings demonstrate a remarkable epidemiological pattern of tuberculosis in Tehran. In group 2, isolates showed a considerably higher frequency compared to isolates in group 3, which is consistent with other findings reported in Iran. However, in contrast to other Iranian studies, no isolated strains were categorized in principal PGG1.
Molecular Detection of Adenoviruses in the Sinus Tissues of Patient by Nested-PCR in Shiraz, Southwest Iran
Authors: Mahmoudvand Shahab , Kord Mohammad , Pirbonyeh Neda , Moattari Afagh , Shokri Somayeh , Zomorodian Kamiar 
Published: September 2019

Background and Aims: Rhinosinusitis is an inflammation of the mucous membrane that may be caused by infectious agents such as bacteria, fungi and viruses. Few studies have been carried out on the role of viruses in Rhinosinusitis patients .The aim of this study was the molecular detection of Adenoviruses in sinus tissues by nested polymerase chain reaction (PCR) in Shiraz.Materials and Methods: In the present study, 103 paraffin-embedded biopsy specimens of sinus tissues were subjected to DNA extraction and tested for adenovirus DNA using Nested PCR. The amplification of a β-globin gene by PCR-based method was used to confirm the quality of extracted DNA.Results: A total of 103 samples of sinus tissues were examined. Of these patients, 50 (48.54%) were male and the rest were female (51.46%). The patients’ age ranged between 2 and 82 years and the mean age was 42.15±1.56 years. The adenovirus DNA was detected in 13 of 103 (12.6%) samples.Conclusions: The results of this study showed that Adenoviruses have high prevalence in rhinosinusitis patients. As a results, it is an important to investigate clinical significance of viral infections especially Adeno viruses in these patients.
The Effect of Incubation Time on the Activity and Stability of Factor VIII during the Preparation Process
Authors: Kabir Kourosh , Hosseini Hassan , Jahed Zargar Mehdy , Mandeh Zeynab , Amrollahi Fatemeh , Farahmandian Navid , Bahreini Elham 
Published: September 2019

Background and Aims: Hemophilia is a rare autoimmune disorder caused by autoantibodies directed in the majority of the cases against clotting factor VIII (FVIII). FVIII is extracted from human plasma or engineered from mammalian cell cultures using recombinant DNA technology. In Iran, most of the used FVIII is prepared from human plasma in Iranian Blood Transfusion Organization. It was seen important to estimate its stability and activity from bleeding time until product preparation.Material and Methods: In the analytical study, 60 healthy male donors (20-50 years old), 15 donors from each blood group, were selected after obtaining informed consent. Donors' blood was collected in QUADRI-PACKs and centrifuged after keeping at 24°C for 2 hours. The separated plasma was divided into three groups and incubated in the lab (22°C) for 0, 90, and 180 minutes, respectively. Then, samples were stored at -20°C for one month. Afterward, the plasma was thawed, and FVIII activity was assayed.Results: The activity of FVIII significantly (p<0.05) reduced by delay in freezing; after the time of 0 min: 134.84%±42, after 90 min: 126.88%±38, after 180 min: 120.22%±34. At all incubation times, the highest and the lowest FVIII activity were observed in A and O blood groups, respectively (p<0.05). FVIII activity was increased along with increasing age up to 35-40, but it decreased in subjects of 40-50 years old. These experiments confirmed that the longer the delay in freezing fresh frozen plasma, the greater the decrease in FVIII stability.Conclusions:. According to the results of this study, the best blood donors for FVIII product are those with blood group A in the age range of 40-35 years.
FROM SOLID SPACES TO LIQUID SPACES: NEW ECOLOGIES OF MUSICAL PRACTICES
Authors: Ribes Adolf Murillo , Riaño Galan María Elena , Gómez Noemy Berbel 
Published: September 2019

Purpose: In recent years, the interest in creating new educational spaces has increased substantially, aiming to influence the methods of learning of our students and to adopt new educational strategies. This article highlights the importance of the atmosphere when remodeling musical practices. Methodologically, when transforming a space, we do not only have to improve the physical architectures but also the pedagogical ones, as well as keeping the practices consistent with these changes. The MUSICLAB CR-209 "Sound laboratory" have been built in Valencia (Spain). This is a hybrid space designed especially for collaborative projects -teachers, artists, students and researchers- in which sound is treated as an element or raw material that can be molded and adapted to what each project demands.
Methodology: The method used in our research was participatory action research. In order to submit the LAB to judgment, three artistic actions were designed and developed.
Results: In this paper, the results showed the main strengths and weaknesses in the design of the space MUSICLAB CR-209 related to the synergies generated through musical practices: the connections established at an interpersonal level, the methodologies and artistic actions developed, the participation and the coordination between the different participants agents. The weaknesses found are related, not so much related to the space itself, but rather to the lack of experiences such as the one described. In this sense, certain barriers and resistances have had to be overcome by all the actors involved.
Implications: In conclusion, we close with a positive vision and we think that this is a novelty experience that stand out for their creativity in the development of contemporary languages and highlight the importance the atmosphere in the educational processes. Our ultimate aim is to provide a proposal that might inspire music and artistic educators when building a new school model more in line with the demands of society s. XXI.
Construcciones geométricas con el paquete tkz-euclide
Authors: Chacón Reiman Y. Acuña , Quesada Estibaliz O. Rojas 
Published: September 2019

El paquete tkz-euclide.sty es un conjunto de macros especializadas en LATEX para realizar construcciones geométricas en dos dimensiones. Está construido sobre PGF (Portable Graphics Format) y su interfaz TikZ. En este documento se explica el uso básico de este paquete así como la realización de algunas construcciones complejas con el fin de que docentes universitarios y de secundaria puedan elaborar material de alta calidad para sus trabajos personales y académicos.
Abstract
The tkz-euclide.sty package is a set of specialized macros in LaTeX to make geometrical constructions in two dimensions. It is built on PGF (Portable Graphics Format) and its TikZ interface.This document explains the basic use of this package as well as the realization of some complex constructions with the purpose of university and secondary teachers for high quality material for their personal and academic works.
A Case of Orbital Langerhans Cell Histiocytosis in an Adult
Authors: Carneiro Inês , Friande António , Araújo Maria 
Published: September 2019

Langerhans cell histiocytosis remains an enigmatic disease with a very heterogeneous presentation. We describe a rare case of orbital Langerhans cell histiocytosis in a 39-year-old female patient who presented right orbital pain and edema of the upper right eyelid. Surgery showed a friable lesion and underlying bone irregularity. Morphological aspects and immunohistochemical profile favored the diagnosis of Langerhans cell histiocytosis, which was confirmed with evidence of Langerin expression. The staging tests did not reveal any organ involvement, so we decided to follow the algorithm proposed by Euro Histio Net: in case of unifocal disease and in a single organ, clinical surveillance was preferred. This case aims to raise awareness of a manifestation of Langerhans cell histiocytosis, which should always be considered as a differential diagnosis in adults with osteolytic orbital lesions.
Eliciting Salient Factors in Online Shopping Behavior Research
Authors: Said Laila Refiana 
Published: September 2019

<p>This paper argues the importance of an exploratory study prior to hypotheses testing in any causal-effect or explanatory predictive behavioral research. It proposes a stage of eliciting salient factors using a framework from theory of planned behavior. The paper opted for an exploratory study by firstly examining 12 academic research of online shopping behavior in Indonesia. Secondly, using the open-ended questions given to 30 respondents, the paper explored reasons respondents shop or not shop online. Those immediate responses were documented and termed as salient factors. Thirdly, the salient factors were then combined with foregone factors based on literature reviews. The final set of factors was chosen as predictive variables in order to provide more accurate potential antecedents for predicting and explaining online shopping behavior. The paper provides sound and practical guidance in eliciting salient factors and formulating a final set of factors in causal-effect/explanatory predictive behavioral research on online shopping behavior. It suggests that academic research should place importance on the stage of eliciting salient factors. Foregone factors are used to strengthen the choice of predictive variables. Both salient and foregone factors are necessary for the final set of factors in such online shopping behavior studies. The paper includes implications for the online vendors and government agencies to promote e-commerce. This paper fulfils a need to conduct exploratory study on online shopping behavior to understand such phenomenon of high internet penetration yet low rate of online buying behavior by focusing on salient factors of the studies. </p>