bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond hypothetical manner: a functional typology of insubordinate como si-clauses
Authors: Royo Viñuales Víctor , Van linden An 
Published: December 2024

Abstract
This article explores the phenomenon of insubordination through the analysis of independent clauses introduced by the conjunction como si ‘as if’ in Spanish. Drawing on present-day corpus data, it proposes a four-way functional typology of insubordinate como si-clauses. In line with previous studies on insubordination, we observe that insubordinate constructions allow speakers to move beyond the prototypical function of como si-clauses observed in subordinate structures, in which they express hypothetical manner. Specifically, we distinguish two types which meet the narrow definition of insubordination in that they combine syntactic with discursive independence, namely denial of an assumption and scalar evaluation, as well as two types that are discursively dependent, and hence instantiate dependency shift, namely nuanced agreement and discursive elaboration or reformulation. In terms of tense-aspect-mood marking, we find that three types consistently show past subjunctive marking, while one type, that of scalar evaluation, invariably shows present indicative verb forms. In terms of discourse-interactional features, we observe that denial of an assumption clauses stand out in favouring dialogic contexts, while the other three types tend to occur in monologic contexts. Within dialogic settings then, all four types are found to be uttered more frequently turn-initially than turn-medially.
On the existence of tripartite graphs and n-partite graphs
Authors: Guo Jiyun , Li Haiyan , Zhang Yuqin , Liu Lingling , Fu Miao 
Published: December 2024

Abstract
A sequence

α

\alpha

of nonnegative integers is said to be graphic if it is the degree sequence of a simple graph

G

G

, and such a graph

G

G

is called a realization of

α

\alpha

. In this article, we generalize Gale and Ryser’s theorem and give the sufficient condition and necessary condition for a triple to be realized by a tripartite graph. Not only that, we also give another stronger monotonous degree condition.
Herod Strategy and a Social Insurance Scheme Against a Short Life: Three Challenges
Authors: Ponthiere Gregory 
Published: December 2024

Abstract
A social insurance scheme against a short life seems impossible: ex ante (before lengths of life are known), it is hard to identify the persons who will be short-lived, and ex post (once lengths of life are known), it is often too late to compensate the short-lived. However, it is possible to insure persons against a short life by means of age-based statistical discrimination that favours the young in line with the Herod strategy: allocating the good things of life to all young adults improves the situation of the unidentified persons who will die prematurely and reduces the deprivation due to an early death. This article examines three challenges questioning the capacity of the Herod strategy to reduce wellbeing deprivation due to a premature death. First, the limited substitutability between the quantity and the quality of life years makes an efficient insurance scheme against a short life incomplete. Second, the state cannot know ex ante the conception of the good life of the short-lived and must offer baskets of universal means that would improve all kinds of short lives. Such baskets will, under endowment effects, affect the adopted views about the good life, against the ideal of a neutral state. Third, the bias towards the future makes persons spontaneously reallocate the good things of life to later ages, which would defeat insurance against a short life.
Geometric nonlinear analysis based on the generalized displacement control method and orthogonal iteration
Authors: Li Ling 
Published: December 2024

Abstract
In response to the shortcomings of insufficient efficiency in calculating geometric nonlinear features and high environmental impact in the current construction, this study explores the control of nonlinear geometric structures based on an updated Lagrangian model function in the construction. In this method, the change in the geometric nonlinear stiffness is analyzed using generalized stiffness parameters and a displacement increment method, and the iteration step size and loading/unloading directions are adjusted in the iteration process to achieve the convergence of the solution. In the simulation experiment, the proposed method took 126 s to calculate the incremental iteration steps 700 times in a conventional environment, which is 28.8% more efficient than the cross-sectional method. In the simulated disaster environment, the model took 1,615 s to calculate the ultimate load of 84 contact elements, which is 43.1% more efficient than the section method and 62.6% more efficient than the discrete analysis method. Experimental results showed that the displacement judgment calculation efficiency of the method proposed in this study is higher than that of other models under different loading and unloading conditions and even in geological disaster states. This method had high environmental adaptability in solving nonlinear building structures and could improve the efficiency of solving general nonlinear building results.
A Case of Successful Treatment of Left Ventricular Rupture after Transcatheter Aortic Valve Implantation
Authors: Tuleutayev Rustem , Abzaliyev Kuat , Kolesnikov Alexey , Kim Igor , Abzaliyeva Symbat 
Published: December 2024

Background: The article talks about a patient who had nonrheumatic disease of the aortic valve and had a left ventricular rupture during a transcatheter aortic valve implantation (TAVI) procedure. Methods: The discrepancy between the size of the prosthesis and the size of the native aortic valve (mismatch) led to the need to deploy a second prosthesis, which was dislocated into the left ventricular cavity and led to myocardial damage and the development of tamponade. Results: As a result of timely cardiac surgery and effective measures of the emergency support service, both prostheses were removed from the left ventricular cavity, the aortic valve was replaced with a “Medtronic Hankock No. 25” biological prosthesis, and the left ventricular myocardial rupture was sutured. Conclusions: In case of the development of such complications during the transcatheter aortic valve implantation (TAVI) procedure with asystole and cardiac tamponade, it was suggested to conduct cardioplegia (instead of chest compressions).
Investigation of Floating Peat Wetlands, Sacramento–San Joaquin Delta, California
Authors:   HydroFocus, Inc., Deverel Steven , Jeffres Carson ,   University of California–Davis, Dore Sabrina ,   HydroFocus, Inc., Corline Nicholas ,   HydroFocus, Inc., Christen Nicholas ,   HydroFocus, Inc., Xu Liyi ,   HydroFocus, Inc., Olds Marc ,   HydroFocus, Inc., Haas Savannah ,   HydroFocus, Inc., Schellenbarger Gregory ,   cbec eco engineering, Eckes Daniel ,   HydroFocus, Inc.
Published: December 2024

Tidal wetland restoration is integral to achieving the Delta coequal goals. Deeply subsided islands limit the potential for tidal wetland restoration. Floating peats may offer an opportunity to create tidal habitat in the subsided western and central Delta. We conducted a mesocosm experiment to assess the feasibility of floating peat blocks, and the potential food-web benefits, biomass production, carbon sequestration, methane emissions, and water-quality effects. We evaluated the effect of varying water residence time and initial peat-block density.

The peat blocks floated during the entire experiment, and accreted biomass at rates consistent with those reported for Delta non-tidal managed wetlands. Peat blocks placed in mesocosms with 45% open water expanded horizontally about 21% per year. We estimated average vertical accretion rates of 5.5 to 8.6 cm yr – 1 for all the mesocosms. Vertical and horizontal expansion increase floating peat-block stability.

We measured a 3-fold zooplankton population increase during the first year after deployment, relative to the Mokelumne River, which was the mesocosm’s water source. Measured and modeled methane emissions were lower than those reported in Delta non-tidal managed wetlands. Aqueous methane concentrations and methane fluxes were significantly lower for the shorter water-residence-time of about 5 days compared to longer residence times of about 11 days. Elevated dissolved oxygen (DO) concentrations generally corresponded with low methane concentrations. Our estimated net ecosystem carbon balance of – 820 +/– 137 g C m – 2 yr – 1 indicates that the floating wetlands are potentially greater carbon sinks than Delta non-tidal wetlands. Nitrogen data indicated consumption by wetland plants, and denitrification and dissimilatory nitrate reduction in the mesocosms. Our preliminary results point to potential ecosystem benefits of floating peats on a larger scale.
Safer Opioid Supply programs: Hydromorphone prescribing in Ontario as a harm reduction intervention to combat the drug poisoning crisis
Authors: Schmidt Rose A. , Guta Adrian , Rai Nanky , Sereda Andrea , O’Reilly Emmet , Hales Jessica , Kolla Gillian , Strike Carol 
Published: December 2024

Abstract
Setting
The crisis of unregulated fentanyl-related overdose deaths presents a significant public health challenge. This article describes the implementation and evaluation of four Safer Opioid Supply programs (SSPs) in Ontario, one in London and three in Toronto.

Intervention and implementation
SSPs aim to curtail overdose fatalities while connecting individuals using drugs to healthcare services. The programs involve a daily dispensed prescription of immediate-release hydromorphone tablets for take-home dosing alongside an observed dose of long-acting opioids like slow-release oral morphine. Implemented within a multidisciplinary primary care framework, these programs emphasize patient-centred approaches and comprehensive health and social support.

Outcomes
In our study conducted in 2020/2021, clients and service providers reported that receiving pharmaceutical opioids through these programs improved the clients’ health and well-being. The regulated supply was reported to lead to decreases in overdose incidents, use of unregulated substances, and criminalized activities. Increased engagement with healthcare and harm reduction services and improvements in social determinants of health, such as food security, were also reported. Despite these positive outcomes, some implementation challenges, including capacity issues and provider burnout, were described by service providers.

Implications
Our findings suggest that the combination of safer supply, wrap-around support, and harm reduction within primary care settings can lead to increased healthcare engagement, HIV/HCV prevention, testing, and treatment uptake, reducing the burden of infectious diseases and overdose risk. SSPs have the potential to meaningfully reduce overdose rates, address the ongoing overdose crisis, and if scaled up, influence population-level outcomes.
Evaluating ChatGPT’s efficacy in addressing common patient questions in plastic surgery consultations
Authors: Brochu Baylee M , Mirsky Nicholas A , Thaller Seth R 
Published: December 2024

Aim: This study aims to investigate the ability of ChatGPT to answer common patient questions related to the five most common aesthetic procedures.
Methods: We asked three questions, two of which were the same across procedures, for each of the five most common plastic surgery procedures as determined by the 2022 American Society of Plastic Surgery (ASPS) Procedural Statistics Release. These were posed to ChatGPT on the same day, using the same account. Then, they were compared to the corresponding information on the ASPS website.
Results: We found that ChatGPT provides accurate, organized, and grammatically correct responses to common patient questions. It was comparable to the ASPS website in terms of comprehensiveness of the complications listed across procedures. However, its responses regarding recovery time were less detailed than the corresponding ASPS articles. It included accurate information on recovery time that was unavailable on the ASPS site. For procedure-specific questions, ChatGPT was more detailed 2/5 times, less detailed 1/5 times, and provided a completely different answer than the ASPS website 2/5 times.
Conclusion: This study provides support for ChatGPT’s utilization as a tool to improve the efficiency of consultations for aesthetic procedures. However, it is important to recognize ChatGPT’s limitations in answering questions in a patient/procedure-specific way. Therefore, it is not a substitute for an experienced surgeon consultation. Further research is needed to assess the reliability of ChatGPT before it can be fully recommended as an ultimate patient learning tool.
RANCANG BANGUN APLIKASI E-BOOKING SHUFF PHOTO STUDIO BERBASIS WEB RESPONSIF
Authors: Wahyudin Widya Cholid 
Published: December 2024

Penelitian ini membahas sistem e-booking yang diimplementasikan oleh Shuff Photo Studio sebagai solusi modern dalam manajemen reservasi, memungkinkan pelanggan untuk melakukan pemesanan kapan saja tanpa batasan waktu. Sistem e-booking ini memungkinkan pelanggan untuk memilih waktu dan jenis layanan yang diinginkan, serta memproses pembookingan menggunakan database MySQL yang menyimpan informasi reservasi secara aman. Metode yang digunakan menggunakan metode Waterfall. Setiap pemesanan ditindaklanjuti dengan konfirmasi melalui email atau pesan. Penelitian ini bertujuan untuk memudahkan pelanggan dalam melakukan reservasi, sistem ini juga mempermudah Shuff Photo Studio dalam mengenalkan produk dan layanan mereka, serta menyediakan proses transaksi yang efisien.

Kata kunci: Database, E-booking, Web Responsive
Complement receptor CD35 on single urinary extracellular vesicle as novel biomarker of sepsis-associated acute kidney injury
Authors: Lv Linli , Li Ning , Tang Tao , Gu Menglei , Fu Yuqi , Qian Weiwei , Ma Nan , Shen Anran , Zhu Tingting , Huo Runbo , Zhang Tao , Xie Jianfeng , Zhang Lu , Liu Bi-Cheng 
Published: December 2024

Abstract

Sepsis-associated acute kidney injury (SA-AKI) portends severe health burden due to significant morbidity and mortality, while early diagnosis remains challenging. In this study, proximity-dependent barcoding assay (PBA) was established to profile the surface proteome of single urinary extracellular vesicle (uEV). Principle uEV clusters with unique function and origination were profiled in SA-AKI. Reduction of complement receptor CD35 on single uEV (CD35-uEV) was revealed as a novel biomarker from one of the main EV clusters with significant proportional differences. CD35-uEV demonstrated high diagnostic accuracy for SA-AKI (receiver operating characteristic-area under the curve (ROC-AUC), 0.98 in screening cohort (n=16), and 0.89 in validation cohort (n=134)). Besides, CD35-uEV enables identification of subclinical AKI (ROC-AUC, 0.84 in prospective cohort (n=72)) which was independent of other clinical parameters as validated by multivariate analysis (p<0.001). Moreover, CD35-uEV correlated closely with AKI severity which also predicts persistent AKI (ROC-AUC, 0.77), progression to AKD (ROC-AUC, 0.66), and mortality risks (ROC-AUC, 0.70). Integrative single-cell and spatial transcriptomics analysis identified that CD35-uEV originated from injured podocyte characterized with diminished CD35 expression. The combination of CD35-uEV with tubular injury biomarkers (TIMP2*IGFBP7) showed improved accuracy in identifying subclinical SA-AKI and prediction of severe stages. Overall, this study identified a novel biomarker on single uEV related to injured podocyte for early diagnosis and risk stratification of SA-AKI.
Influence of metamorphism degree on coal gas desorption characteristics and dynamics models
Authors: Xu Huigang , Qi Xuyao , Wang Haidong , Liang Zhongqiu , Yang Tao , Zou Yongming , Jiang Qi , Jin Lei 
Published: December 2024

Abstract

Elucidating the characteristics of desorption and diffusion of coal seam gas is essential for the prevention of gas disasters in coal mines. In this study, constant-temperature gas dispersion tests were conducted on lignite, fiery coal, and anthracite to unveil the intricate dynamics of gas diffusion in coal samples under the influence of coal metamorphism. The primary focus was to determine their gas desorption and diffusion characteristics and analyze the mathematical expressions of gas dispersion for coal samples with varying levels of metamorphism during different periods. The findings revealed that coal samples with high metamorphism could attain the desorption limit relatively swiftly, while low-rank lignite required a longer duration to reach the limit. Notably, the gas desorption diffusion rate exhibited significant sensitivity to the coal's metamorphism level. The gas desorption rate within the first 10 minutes was observed to be stable for lignite and fiery coal, while anthracite displayed a faster desorption rate in the initial 4 minutes followed by stability in the subsequent 6 minutes. Furthermore, the effective gas diffusion coefficient demonstrated a robust negative linear correlation with the degree of metamorphism, signifying a decrease in gas diffusion ability with an increase in metamorphism level. Empirical formulas employed to fit anthracite yielded relatively stable correlation indices, with Formula 3 deemed more suitable for depicting the gas desorption processes of lignite and fiery coal.
Polysaccharide from Ganoderma sinense improves cognitive capacity in a mouse model of Alzheimer’s disease via reshaping the gut microbiota and short-chain fatty acid metabolism
Authors: Bian Wenjuan , Wang Jiaxuan , Jin Yudi , Ji Hong , Li Wei , Wu Hui , Li Wei , Zhang Wenhui , Zhang Linbo , Fu Lu 
Published: December 2024

Abstract

Two types of polysaccharides from Ganoderma sinense termed GSP1 (Mw: 58.92 kDa, consisting of fourteen monosaccharides) and GSP2 (Mw: 3.27 kDa, consisting of fourteen monosaccharides) were purified, and their protective effects against Alzheimer's disease (AD) in a mouse model were investigated. An in vitro study suggested that GSPs protect SH-SY5Y cells from neurotoxicity and oxidative stress in response to glutamate. The effect of GSP1 on the cognitive and memory capacity of the AD mouse model was confirmed using the Morris Water Maze, Object Recognition, and Nestlet Shredding tests. Additionally, treatment with GSP1 could reduce the amyloid β plaques in the brains of AD mice. Multi-omics analysis of the gut microbiome, short-chain fatty acid (SCFAs) metabolomics, and behavioral tests were conducted to elucidate the therapeutic mechanisms of GSPs. The results revealed that GSP1 improved the diversity of the microbiome, restored the structure of the gut microflora, and regulated SCFA metabolism. Four genera (Turicibacter, Jeotgalicoccus, Staphylococcusa, and Odoribacter) were significantly associated with both behavioral tests and SCFAs metabolism in the GSP1-treated group. These findings provide a basis for the development of polysaccharide drugs against AD and for further development of GSP1.
Predictors of short stature in Israeli children aged 6–7 years: a retrospective cohort study
Authors: Fisch-Shvalb Naama , Yackobovitch-Gavan Michal , Fliss-Isakov Naomi , Morali Yair , Brooks Nati , Magnazi Moran Blaychfeld , Zimmerman Deena Rachel , Lazar Liora , Phillip Moshe , Endevelt Ronit 
Published: December 2024

Abstract

Background
There are differences in the rates of short stature (WHO height-z score < -2SD) between the various sectors in Israeli children aged 6–7 years, with higher rates in the ultraorthodox Jewish population. We aimed to: (a) Compare the anthropometric data at 0–2 years of age and the obstetric and demographic data of children with short stature at 6–7 years of age with those of children with normal height. (b) Assess risk factors for short stature at the age of 6–7 years. (c) Evaluate the impact of clinical and socioeconomic factors on linear growth from birth to the age of 6–7 years.
Methods
This was a retrospective cohort study. Anonymized anthropometric data measured at the first grade of school during 2015–2019 were collected from the Ministry of Health records. The participants were stratified into sectors according to the affiliation of their school. Retrospective growth and sociodemographic data were extracted for each child from the national birth registry and Maternal Child Health Clinics files.
Results
The cohort included 368,088 children, with a median age of 6.7 years (IQR 6.3,7.0). Short stature was more prevalent in ultraorthodox Jewish boys (3.8%) and girls (3.2%), and least prevalent in Arab boys (0.8%) and girls (0.7%) compared with all other sectors (P < 0.001). The rate of stunting in Bedouin children was similar to that in the general population (1.6%). In a logistic regression model, the variables that predicted short stature at the age of 6–7 years were female sex, longer gestation, lower height-z score at 2 months of age, birth weight < 90th percentile, being in the ultraorthodox Jewish sector, and a smaller change in height-z score until 2 years of age.
Conclusions
Growth gaps between different sectors of school-aged Israeli children emerge during the first 2 years of life. The most vulnerable population for stunting is the ultraorthodox population. Public health services, including MCH clinics and primary caregivers, should prioritize this group and closely monitor for growth faltering during the first and second years of life.
The cardiovascular benefits of dark chocolate supplementation during high-intensity resistance exercise in the early follicular and mid-luteal phases of the menstrual cycle
Authors: Wang Chun Wei , Fang Shih-Hua , Yu Tse-An , Chen Liang-You , Wang Chung-Kai , Wang Soun-Cheng , He Cheng-Shiun 
Published: December 2024

Abstract

Background:
Dark chocolate, rich in flavanols, may support vascular health by reducing arterial stiffness and blood pressure across menstrual phases. This study examined the effects of 85% dark chocolate on nitric oxide (NO) levels and vascular function during high-intensity resistance exercise in healthy women across the early follicular and mid-luteal phases.
Methods:
Thirty-one healthy women (aged 20–30 years) with regular menstrual cycles completed a randomized, crossover study. Participants consumed either 85% dark chocolate or milk chocolate (1g/kg body weight) before high-intensity resistance exercise during the early follicular (days 2–5) and mid-luteal (days 18–24) phases of two menstrual cycles. Finger-toe pulse wave velocity (ftPWV), arterial stiffness, blood pressure, and plasma NO levels were measured at rest, 2 hours after chocolate consumption (baseline), immediately post-exercise (T0), and at 60 (T60) and 120 (T120) minutes post-exercise.
Results:
Dark chocolate supplementation significantly increased NO levels and reduced systolic blood pressure (SBP), ftPWV, and arterial pressure volume index (API) (p < 0.05) compared to milk chocolate across both menstrual phases. During the early follicular phase, dark chocolate also attenuated exercise-induced increases in arterial stiffness and blood pressure (p < 0.05).
Conclusion:
85% dark chocolate supplementation may reduce the negative vascular effects of high-intensity resistance exercise, particularly by lowering blood pressure, arterial stiffness, and API, especially in the early follicular phase. These findings suggest that dark chocolate could be a practical, non-pharmacological intervention for improving cardiovascular health in women.