bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Polar Stratosphere as an Arbiter of the Projected Tropical Versus Polar Tug of War
Authors: Peings Yannick , Cattiaux Julien , Magnusdottir Gudrun 
Published: August 2019

AbstractThis study explores the “tug of war” between the effects of Arctic amplification (“AA”) and upper‐troposphere tropical warming (“UTW”) on the response of the future North Atlantic atmospheric circulation. The late 21st century AA and UTW temperature anomalies are imposed in a high‐top atmospheric model by nudging the temperature. Two sets of experiments are performed, with and without feedback of the polar stratosphere to highlight its role in the response to UTW, AA, and both combined. With interactive polar stratosphere, UTW forces an equatorward shift of the eddy‐driven jet that reinforces the response to AA. However, when the polar stratosphere feedback is suppressed, the response to UTW is opposite and reflects the previously identified tug of war between the effects of UTW and AA in midlatitudes. This study highlights that the polar stratosphere is a key component for future changes in the North Atlantic atmospheric circulation and that it must be accurately represented in climate change scenarios.
Cross‐Scale Interactions Dictate Regional Lake Carbon Flux and Productivity Response to Future Climate
Authors: Zwart J. A. , Hanson Z. J. , Read J. S. , Fienen M. N. , Hamlet A. F. , Bolster D. , Jones S. E. 
Published: August 2019

AbstractLakes support globally important food webs through algal productivity and contribute significantly to the global carbon cycle. However, predictions of how broad‐scale lake carbon flux and productivity may respond to future climate are extremely limited. Here, we used an integrated modeling framework to project changes in lake‐specific and regional primary productivity and carbon fluxes under 21st century climate for thousands of lakes. We observed high uncertainty in whether lakes collectively were to increase or decrease lake CO2 emissions and carbon burial in our modeled region owing to divergence in projected regional water balance among climate models. Variation in projected air temperature influenced projected changes in lake primary productivity (but not CO2 emissions or carbon burial) as warmer air temperatures decreased productivity through reduced lake water volume. Cross‐scale interactions between regional drivers and local characteristics dictated the magnitude and direction of lake‐specific carbon flux and productivity responses to future climate.
The Geometry of an Electron Scale Magnetic Cavity in the Plasma Sheet
Authors: Liu H. , Zong Q.‐G. , Zhang H. , Sun W. J. , Zhou X.‐Z. , Gershman Daniel J. , Shi C. , Zhang K. , Le Guan , Pollock C. 
Published: August 2019

AbstractElectron scale magnetic cavities are electron vortex structures formed in turbulent plasma, while the evolution and electron dynamics of these structures have not been fully understood. Recently, high‐energy, angular, and temporal electron measurements from Magnetospheric Multiscale have enabled the application of an energetic particle sounding technique to these structures. This study analyzes an electron scale magnetic cavity observed by Magnetospheric Multiscale on 7 May 2015 in the plasma sheet. A comprehensive sounding technique is applied to obtain the geometry and propagation velocities of the boundaries. The result shows that the scale size of the structure is ∼90 km, and the leading and trailing boundaries are moving in the same direction but with different speeds (∼11.5 ± 2.2 and ∼18.1 ± 3.4 km/s, respectively). The speed difference suggests a shrinking of the structure that may play a significant role in magnetic energy dissipation and electron energization of electron scale magnetic cavities.
Multimodel Analysis of the Atmospheric Response to Antarctic Sea Ice Loss at Quadrupled CO2
Authors: Ayres H.C. , Screen J.A. 
Published: August 2019

AbstractAntarctic sea ice cover is projected to significantly decrease by the end of the twenty‐first century if greenhouse gas concentrations continue to rise, with potential consequences for Southern Hemisphere weather and climate. Here we examine the atmospheric response to projected Antarctic sea ice loss at quadrupled CO2, inferred from 11 Coupled Model Intercomparison Project phase 5 models. Our study is the first multimodel analysis of the atmospheric response to Antarctic sea ice loss. Projected sea ice loss enhances the negative phase of the Southern Annular Mode, which slightly damps the positive Southern Annular Mode response to increased CO2, particularly in spring. The negative Southern Annular Mode response largely reflects a weakening of the eddy‐driven jet, and to a lesser extent, an equatorward shift of the jet. Sea ice loss induces near‐surface warming over the high‐latitude Southern Ocean, but warming does not penetrate over the Antarctic continent. In spring, we find multimodel evidence for a weakened polar stratospheric vortex in response to sea ice loss.
The Distinction Between the Gulf Stream and Its North Wall
Authors: Chi Lequan , Wolfe Christopher L. P. , Hameed Sultan 
Published: August 2019

AbstractDownstream of Cape Hatteras, the Gulf Stream (GS) is bounded to the north by a sharp temperature front known as the North Wall (NW). Previous studies have generally assumed that variations of the NW and GS are equivalent. Using satellite sea surface height to identify the GS and the 15 °C isotherm at 200‐m depth to represent the NW, this paper examines their similarities and differences during 1993–2016. The NW and GS are geographically close and vary similarly only to the west of 71°W. Downstream of that, they rapidly diverge—and the variances of their latitudes increase by more than a factor of 2—as the GS flows past the New England Seamounts. Evidence is presented to show that the difference in properties of the NW and the GS is related to the presence of mesoscale eddies in the region separating them.
ULF Waves Modulating and Acting as Mass Spectrometer for Dayside Ionospheric Outflow Ions
Authors: Liu Z.‐Y. , Zong Q.‐G. , Zhou X.‐Z. , Hao Y. X. , Yau A. W. , Zhang H. , Chen X.‐R. , Fu S. Y. , Pollock C. J. , Le G. , Ergun R. E. , Lindqvist P.‐A. 
Published: August 2019

AbstractIonospheric outflow has been shown to be a dominant ion source of Earth's magnetosphere. However, most studies in the literature are about ionospheric outflow injected into the nightside magnetosphere. We still know little about ionospheric outflow injected into the dayside magnetosphere and its further energization after it enters the magnetosphere. Here, with data from Magnetospheric Multiscale mission, we report direct observations of the modulation of dayside ionospheric outflow ions by ultralow frequency (ULF) waves. The observations indicate that the modulation is mass dependent, which demonstrates the possibility of using ULF waves as a mass spectrometer to identify ion species. Moreover, the measurement suggests that polarization drift may play a role in O+ modulation, which may lead to a true acceleration and even nonadiabatic behavior of O+. This interaction scenario can work throughout the whole magnetosphere and impact upon the plasma environment and dynamics.
Ross Ice Shelf Icequakes Associated With Ocean Gravity Wave Activity
Authors: Chen Z. , Bromirski P. D. , Gerstoft P. , Stephen R. A. , Lee W. S. , Yun S. , Olinger S. D. , Aster R. C. , Wiens D. A. , Nyblade A. A. 
Published: August 2019

AbstractGravity waves impacting ice shelves illicit a suite of responses that can affect ice shelf integrity. Broadband seismometers deployed on the Ross Ice Shelf, complemented by a near‐icefront seafloor hydrophone, establish the association of strong icequake activity with ocean gravity wave amplitudes (AG) below 0.04 Hz. The Ross Ice Shelf‐front seismic vertical displacement amplitudes (ASV) are well correlated with AG, allowing estimating the frequency‐dependent transfer function from gravity wave amplitude to icefront vertical displacement amplitude (TGSV(f)). TGSV(f) is 0.6–0.7 at 0.001–0.01 Hz but decreases rapidly at higher frequencies. Seismicity of strong icequakes exhibits spatial and seasonal associations with different gravity wave frequency bands, with the strongest icequakes observed at the icefront primarily during the austral summer when sea ice is minimal and swell impacts are strongest.
Interhemispheric Asymmetry in Response of Low‐Latitude Ionosphere to Perturbation Electric Fields in the Main Phase of Geomagnetic Storms
Authors: Dashora N. , Suresh Sunanda , Niranjan K. 
Published: August 2019

AbstractStructures of sudden enhancements/depressions and associated interhemispheric asymmetry in low‐latitude total electron content (TEC) during the main phase (MP) of geomagnetic storms have remained unpredictable majorly due to oscillating equatorial vertical E×B drifts and resultant redistribution of plasma in low latitudes in a given seasonal background. Robust analysis of 7 major and 30 moderate ionospheric storms during the years 2000–2018 is performed with comprehensive literature review encompassing various sources of asymmetry in magnetosphere‐ionosphere coupling. Taking advantage of simultaneous long‐term observations of E×B drift from Jicamarca, H component from magnetometers, and global ionospheric map vertical TEC (VTEC) and TEC observations across the dip equator from the South American sector, simultaneous formation of peaks and valleys in VTEC and associated asymmetry are studied. Additionally, a three‐layer neural network‐based E×B drift model is developed using delta‐H observations that provide drift estimates in the absence of Jicamarca drifts. The main results establish simultaneous high‐magnitude short‐lived (1–2 hr) enhancements and depression in VTEC during the MP in daytime in both hemispheres with varying differences of −30 to 100 TECU with respect to quiet time mean and along with prominent existence of interhemispheric asymmetry in TEC during the MP regardless of seasons. Maximum VTEC in the northern and southern low latitudes is found to occur at different times during storms. Large difference of VTEC is found ranging between 10 and 30 TECU between the near conjugate locations of the hemispheres. Coincident global episodic peaks marked by steep VTEC falls show dominance of episodic eastward and westward penetration electric fields in the low‐latitude daytime ionosphere.
Stochastic Differential Equations for the Variability of Atmospheric Convection Fluctuating Around the Equilibrium
Authors: Machulskaya E. , Seifert A. 
Published: August 2019

AbstractMost convection parameterization schemes used within current atmospheric models make a convective equilibrium assumption, which breaks at the resolutions currently used by many numerical weather prediction models. To account for fluctuations of the cloud base mass flux about its equilibrium value, stochastic convection schemes have been developed for both deep (Plant & Craig, 2008, https://doi.org/10.1175/2007JAS2263.1) and shallow (Sakradzija et al., 2015, https://doi.org/10.5194/npg-22-65-2015) convection. Due to the need to explicitly track individual clouds in each grid box, these schemes can be computationally expensive. Motivated by the above considerations, the present study demonstrates how the machinery of the above schemes can be reduced to the solution of two ordinary stochastic differential equations for the cloud number and the total cloud base mass flux. The properties of the resulting stochastic processes for the cloud number and the total mass flux are not exactly equivalent to those of the original schemes but recover them to a very good approximation.
Polyphase Magmatism During the Formation of the Northern East Greenland Continental Margin
Authors: Franke D. , Klitzke P. , Barckhausen U. , Berglar K. , Berndt C. , Damm V. , Dannowski A. , Ehrhardt A. , Engels M. , Funck T. , Geissler W. , Schnabel M. , Thorwart M. , Trinhammer Per 
Published: August 2019

AbstractNew marine geophysical data acquired across the partly ice‐covered northern East Greenland continental margin highlight a complex interaction between tectonic and magmatic events. Breakup‐related lava flows are imaged in reflection seismic data as seaward dipping reflectors, which are found to decrease in size both northward and southward from a central point at 75°N. We provide evidence that the magnetic anomaly pattern in the shelf area is related to volcanic phases and not to the presence of oceanic crust. The remnant magnetization of the individual lava flows is used to deduce a relative timing of the emplacement of the volcanic wedges. We find that the seaward dipping reflectors have been emplaced over a period of 2–4 Ma progressively from north to south and from landward to seaward. The new data indicate a major post‐middle Eocene magmatic phase around the landward termination of the West Jan Mayen Fracture Zone. This post‐40‐Ma volcanism likely was associated with the progressive separation of the Jan Mayen microcontinent from East Greenland. The breakup of the Greenland Sea started at several isolated seafloor spreading cells whose location was controlled by rift structures and led to the present‐day segmentation of the margin. The original rift basins were subsequently connected by steady‐state seafloor spreading that propagated southward, from the Greenland Fracture Zone to the Jan Mayen Fracture Zone.
Plasma neurofilament light chain concentration is increased in anorexia nervosa
Authors: Nilsson Ida A. K. , Millischer Vincent , Karrenbauer Virginija Danylaité , Juréus Anders , Salehi Alireza M. , Norring Claes , von Hausswolff-Juhlin Yvonne , Schalling Martin , Blennow Kaj , Bulik Cynthia M. , Zetterberg Henrik , Landén Mikael 
Published: August 2019

AbstractAnorexia nervosa (AN) is a severe psychiatric disorder with high mortality and, to a large extent, unknown pathophysiology. Structural brain differences, such as global or focal reductions in grey or white matter volumes, as well as enlargement of the sulci and the ventricles, have repeatedly been observed in individuals with AN. However, many of the documented aberrances normalize with weight recovery, even though some studies show enduring changes. To further explore whether AN is associated with neuronal damage, we analysed the levels of neurofilament light chain (NfL), a marker reflecting ongoing neuronal injury, in plasma samples from females with AN, females recovered from AN (AN-REC) and normal-weight age-matched female controls (CTRLS). We detected significantly increased plasma levels of NfL in AN vs CTRLS (medianAN = 15.6 pg/ml, IQRAN = 12.1–21.3, medianCTRL = 9.3 pg/ml, IQRCTRL = 6.4–12.9, and p < 0.0001), AN vs AN-REC (medianAN-REC = 11.1 pg/ml, IQRAN-REC = 8.6–15.5, and p < 0.0001), and AN-REC vs CTRLS (p = 0.004). The plasma levels of NfL are negatively associated with BMI overall samples (β (±se) = −0.62 ± 0.087 and p = 6.9‧10−12). This indicates that AN is associated with neuronal damage that partially normalizes with weight recovery. Further studies are needed to determine which brain areas are affected, and potential long-term sequelae.
Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy
Authors: Gao Ang , Hu Xian-li , Saeed Madiha , Chen Bin-fan , Li Ya-ping , Yu Hai-jun 
Published: August 2019

AbstractThe clinical performance of conventional cancer therapy approaches (surgery, radiotherapy, and chemotherapy) has been challenged by tumor metastasis and recurrence that is mainly responsible for cancer-caused mortalities. The cancer immunotherapy is being emerged nowadays as a promising therapeutic modality in order to achieve a highly efficient therapeutic performance while circumventing tumor metastasis and relapse. Liposomal nanoparticles (NPs) may serve as an ideal platform for systemic delivery of the immune modulators. In this review, we summarize the cutting-edge progresses in liposomal NPs for cancer immunotherapy, with focus on dendritic cells, T cells, tumor cells, natural killer cells, and macrophages. The review highlights the major challenges and provides a perspective regarding the clinical translation of liposomal nanoparticle-based immunotherapy.
Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility
Authors: Silva Ana I. , Haddon Josephine E. , Ahmed Syed Yasir , Trent Simon , Lin Tzu-Ching E. , Patel Yateen , Carter Jenny , Haan Niels , Honey Robert C. , Humby Trevor , Assaf Yaniv , Owen Michael J. , Linden David E. J. , Hall Jeremy , Wilkinson Lawrence S. 
Published: August 2019

AbstractThe biological basis of the increased risk for psychiatric disorders seen in 15q11.2 copy number deletion is unknown. Previous work has shown disturbances in white matter tracts in human carriers of the deletion. Here, in a novel rat model, we recapitulated low dosage of the candidate risk geneCYFIP1present within the 15q11.2 interval. Using diffusion tensor imaging, we first showed extensive white matter changes inCyfip1mutant rats, which were most pronounced in the corpus callosum and external capsule. Transmission electron microscopy showed that these changes were associated with thinning of the myelin sheath in the corpus callosum. Myelin thinning was independent of changes in axon number or diameter but was associated with effects on mature oligodendrocytes, including aberrant intracellular distribution of myelin basic protein. Finally, we demonstrated effects on cognitive phenotypes sensitive to both disruptions in myelin and callosal circuitry.
The determinants of genetic diversity in butterflies
Authors: Mackintosh Alexander , Laetsch Dominik R. , Hayward Alexander , Charlesworth Brian , Waterfall Martin , Vila Roger , Lohse Konrad 
Published: August 2019

AbstractUnder the neutral theory, genetic diversity is expected to increase with population size. While comparative analyses have consistently failed to find strong relationships between census population size and genetic diversity, a recent study across animals identified a strong correlation between propagule size and genetic diversity, suggesting that r-strategists that produce many small offspring, have greater long-term population sizes. Here we compare genome-wide genetic diversity across 38 species of European butterflies (Papilionoidea), a group that shows little variation in reproductive strategy. We show that genetic diversity across butterflies varies over an order of magnitude and that this variation cannot be explained by differences in current abundance, propagule size, host or geographic range. Instead, neutral genetic diversity is negatively correlated with body size and positively with the length of the genetic map. This suggests that genetic diversity is determined both by differences in long-term population size and the effect of selection on linked sites.
Arctic–Eurasian climate linkage induced by tropical ocean variability
Authors: Matsumura Shinji , Kosaka Yu 
Published: August 2019

AbstractEurasian continent has experienced cold winters over the past two decades in contrast with Arctic warming. Previous studies have suggested that the cold Eurasian winters are associated with Arctic sea-ice loss, while others attributed them to atmospheric internal variability. However, here we show that the Arctic and Eurasian climate linkage is driven by the combination between atmospheric teleconnection originating in the tropical oceans and Arctic sea ice. Like a battery charges a capacitor, El Niño heats the tropical Atlantic, and the warmer Atlantic condition persists until early winter of El Niño-decay year. We find that the persisting tropical Atlantic warming induces anomalous Rossby wave train arching to Eurasia, leading to Arctic sea-ice increase and Eurasian warming. In La Niña phase these changes are reversed. Our results therefore suggest that the combination of recent tropical Pacific cooling and Arctic sea-ice loss have contributed to the frequent Eurasian cold winters.
Weathering in a world without terrestrial life recorded in the Mesoproterozoic Velkerri Formation
Authors: Rafiei Mehrnoush , Kennedy Martin 
Published: August 2019

AbstractToday the terrestrial surface drives biogeochemical cycles on Earth through chemical weathering reactions mediated by the biological influence of soils. Prior to the expansion of life on to land, abiotic weathering may have resulted in different boundary conditions affecting the composition of the biosphere. Here we show a striking difference in weathering produced minerals preserved in the Mesoproterozoic Velkerri Formation. While the bulk chemistry and mineralogy is dominated by illite similar to many modern mudstones, application of a novel microbeam technology reveals that the initial detrital minerals were composed of mica (28%) and feldspar (45%) with only a trace amount (<2%) of typical soil formed clay minerals. The majority of illite and the high Al2O3 fraction previously interpreted as a weathering signal, is present as a replacement of feldspar and mica. These sediments record physical erosion with limited pedogenic clay mineral formation implying fundamentally different weathering pathways.
Vertical redistribution of salt and layered changes in global ocean salinity
Authors: Liu Chao , Liang Xinfeng , Ponte Rui M. , Vinogradova Nadya , Wang Ou 
Published: August 2019

AbstractSalinity is an essential proxy for estimating the global net freshwater input into the ocean. Due to the limited spatial and temporal coverage of the existing salinity measurements, previous studies of global salinity changes focused mostly on the surface and upper oceans. Here, we examine global ocean salinity changes and ocean vertical salt fluxes over the full depth in a dynamically consistent and data-constrained ocean state estimate. The changes of the horizontally averaged salinity display a vertically layered structure, consistent with the profiles of the ocean vertical salt fluxes. For salinity changes in the relatively well-observed upper ocean, the contribution of vertical exchange of salt can be on the same order of the net surface freshwater input. The vertical redistribution of salt thus should be considered in inferring changes in global ocean salinity and the hydrological cycle from the surface and upper ocean measurements.
Chemical mimicry of viral capsid self-assembly via corannulene-based pentatopic tectons
Authors: Chen Yu-Sheng , Solel Ephrath , Huang Yi-Fan , Wang Chien-Lung , Tu Tsung-Han , Keinan Ehud , Chan Yi-Tsu 
Published: August 2019

AbstractSelf-assembly of twelve pentatopic tectons, which have complementary edges or can be linked using either digonal or trigonal connectors, represents the optimal synthetic strategy to achieve spherical objects, such as chemical capsids. This process requires conditions that secure uninterrupted equilibria of binding and self-correction en route to the global energy minimum. Here we report the synthesis of a highly soluble, deca-heterosubstituted corannulene that bears five terpyridine ligands. Spontaneous self-assembly of twelve such tectons with 30 cadmium(II) cations produces a giant icosahedral capsid as a thermodynamically stable single product in high yield. Nuclear magnetic resonance (NMR) methods, mass spectrometry analyses, small-angle X-ray scattering, transmission electron microscopy, and atomic force microscopy indicate that this spherical capsid has an external diameter of nearly 6 nm and shell thickness of 1 nm, in agreement with molecular modeling. NMR and liquid chromatography evidences imply that chiral self-sorting complexation generates a racemic mixture of homochiral capsids.