bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE URGENCY OF GENETIC VERIFICATION OF NON-COMPACTION CARDIOMYOPATHY IN CHILDREN: CLINICAL CASES
Authors: Sdvigova Nataliya A. , Basargina Elena N. , Ryabtsev Dmitry V. , Savostyanov Kirill V. , Pushkov Alexander A. , Zhurkova Natalia V. , Revunenkov Grigory V. , Zharova Olga P. 
Published: July 2018

Background. Non-compaction cardiomyopathy is a group of genetically heterogeneous, poorly studied myocardial diseases with a variety of clinical manifestations (from asymptomatic course to progressive systolic dysfunction with symptoms of chronic heart failure, arrhythmias, and thromboembolic complications). Considering the variety of genetic disorders associated with the development of noncompaction cardiomyopathy, genetic verification of the diagnosis is important for determining the prognosis and conducting genetic counselling of families with cases of the disease.Description of the Clinical Case. The article presents two clinical observations of a severe course of non-compaction cardiomyopathy with remodeling of the heart cavities according to the dilated phenotype. In order to clarify the disease etiology, a molecular genetic study was conducted using the method of direct automatic sequencing with the analysis of targeted regions of 404 genes which mutations are described in hereditary diseases of the heart and blood vessels. After verifying the mutation (in the ACTC1 and MYBPC3 genes), we performed a search for the detected nucleotide substitution in the venous blood samples of parents and in one case — in the fetal DNA sample. The mode of inheritance has been determined; the probability of recurrence of the disease in siblings in subsequent pregnancies has been estimated.Conclusion. The description of clinical cases shows the importance of genetic verification of the diagnosis in patients with non-compaction cardiomyopathy for determining the disease prognosis and developing an algorithm for monitoring relatives of a proband.
APPLICATION OF INTERVALIC HYPOXIC-HYPEROXIC ENTRAINMENT TO PREVENTION OF INTRA AND EARLY POSTOPERATIONAL COMPLICATIONS IN CORONARY BYPASS GRAFTING
Authors: Tuter D. S. , Komarov R. N. , Glazachev O. S. , Syrkin A. L. , Severova L. P. , Ivanova E. V. , Kopylov F. Yu. 
Published: July 2018

Aim.To assess possibility and safety of intervalic hypoxic-hyperoxic training (HHT) as a method of cardioprotection and metabolic adaptation of myocardium for onpump coronary bypass surgery.Material and methods.Totally, 80 coronary heart disease patients included, hospitalized to the clinics of aortic and cardiosurgery of the University hospital of Sechenov University. All had indications for the operation — direct myocardial revascularization with bypass grafting. In 5 days before surgery, according to the scheme of preparation, the patients were randomized to two groups (main — with HHT, and controls; n=40). The rate of complications was evaluated, during the operation and in post-surgery period. The level of troponin I was measured before operation, in 2 and 24 hours after, as well as level of lactate in venous blood before and after operation.Results.The rate of intraand early postsurgery complications in both groups did not differ significantly, though in the main there was tendency to decline of total rate of complications. In patients of HHT group median troponin I was significantly lower: 1,068 (0,388; 1,397) ng/L, when in controls — 1,980 (1,068; 3,239) ng/mL, р=0,012.Lactate level after HHT operation was significantly lower — 1,74 (1,23; 2,04) mM/L, comparing to the controls — 2,10 (1,80; 2,29) mM/L, р=0,04.Conclusion.The applicability and safety were demonstrated, of HHT as a method of cardioprotection in shunting of coronary arteries on-pump. Taken low number of participants, it is important to conduct broader investigation on this type of entrainment.
AN OVERTRAINING SYNDROME AS FUNCTIONAL CARDIOVASCULAR DISORDER DUE TO PHYSICAL OVERLOAD
Authors: Badtieva V. A. , Pavlov V. I. , Sharykin A. S. , Khokhlova М. N. , Pachina A. V. , Vybornov V. D. 
Published: July 2018

In the article, an analysis provided of recent views on the overtraining syndrome by the data from local and foreign publications.The witness of the problem actuality is also an existence of controversial opinions and absence of clear definitions on properties of the condition. It has been revealed that the main role in pathogenesis of the overtraining syndrome do play the changes of cardiovascular, endocrine and central nervous systems. These changes are complicated and ambiguous, depend upon multiple factors, as the type of sport, specifics of exertion and loads, stage of pathophysiological process. Entraining effect of exertion, if incorrectly utilized, underestimation of current condition of a sportsman, might not lead to expected results. Moreover, non-rational application of exertion might lead to opposite effect, that is, to decrease adaptation potential and reserves, towards the edge of the condition as an overtraining syndrome, which shows phasic, progressing character, starting from fatigue and mild disorders, to persistent, rigidly reversible processes.Due to controversy, multiple stages and multifactorial of the overtraining syndrome, by now there is no unified approach to its definition, as no unified standards to its diagnostics, treatment and prevention.
Stres akademis berhubungan dengan kualitas hidup pada remaja
Authors: Haryono R Harvilia Safira , Kurniasari Kurniasari 
Published: July 2018

LATAR BELAKANGMasa remaja adalah periode usia yang berkisar dari 10-19 tahun. Remaja merupakan salah satu penentu indeks pembangunan manusia. Pembangunan ini bertujuan untuk meningkatkan kualitas hidup masyarakat. Kualitas hidup remaja dipengaruhi oleh banyak faktor, terutama faktor fisik dan psikologis. Pada remaja terjadi perubahan yang signifikan pada kedua faktor tersebut. Hal ini menyebabkan remaja menjadi rentan terhadap stres. Salah satu stres yang dapat dialami remaja adalah stres akademis. Stres akan mengakibatkan perubahan biokimia, psikologis, dan perilaku, kondisi ini dapat menyebabkan penurunan kesehatan fisik, psikologis, dan hubungan sosial sehingga mengakibatkan penurunan kualitas hidup. Penelitian ini bertujuan untuk menganalisa hubungan antara stress akademik dan kualitas hidup pada remaja.
METODEPenelitian ini merupakan studi cross sectional dengan responden berjumlah 233 siswa di SMAN 1 Cileungsi, Kab. Bogor. Pengumpulan data menggunakan kuesioner Educational Stres Scale for Adolescent (ESSA) dan kuesioner Multidimensional Students’ Life Satisfaction Scale-Adolescent (MSLSS). Analisis data dengan uji Chi-Square menggunakan program SPSS dengan tingkat kemaknaan sebesar 0,05.
HASILDari 233 responden, 70% berjenis kelamin perempuan, 30% laki-laki, 15,5% tegolong stres ringan, 51,1% stres sedang, dan 33,5% stres berat, 50,2% memiliki kualitas hidup kurang dan 49,8% kualitas hidup baik. Uji Chi-Square menunjukkan terdapat hubungan yang bermakna antara stres akademis dan kualitas hidup pada remaja (p = 0,044).
KESIMPULANStres akademis merupakan salah satu jenis stres yang dapat mempengaruhi kualitas hidup pada remaja.
SAĞLIK MESLEK GRUPLARINDA HUBRİS SENDROMUNUN VARLIĞINA İLİŞKİN KEŞFEDİCİ BİR ÇALIŞMA
Authors: UYSAL Şerife Alev , ÇELİK Rukiye 
Published: July 2018

Özellikle 20.
Yüzyılın ilk yarısında tıbbi bir egemenlik meydana gelmiştir. Tıbbi egemenlik;
tıbbi bakım sırasında ortaya çıkan iş bölümü içerisinde mesleki anlamda
üstünlüğü de beraberinde getirmiştir. Hubris sendromu, gücü elinde bulundurma
arzusu ile anormal davranış arasındaki bağlantıya odaklanan bir kavramdır.
Modern tıbbın getirdiği tıbbi egemenlik, sağlık alanında neredeyse her şeyin
başarılabilir inancını ortaya çıkartmıştır. Çalışmanın amacı; sağlık meslek
gruplarında hubris sendromunun var olup olmadığını tespit etmektir. Çalışma; nitel araştırma desenlerinden
olgubilim desenine uygun olarak yürütülmüştür. Çalışmanın örneklemi amaçlı
örnekleme ile belirlenmiş ve bu kapsamda 33 sağlık çalışanı ile yarı yapılandırılmış
mülakatlar gerçekleştirilmiştir. Veriler
betimsel analiz çerçevesinde sürekli karşılaştırma tekniği ile ağaç, açık ve
seçici kodlamaya tabi tutulmuştur. Araştırmanın sonucunda sağlık çalışanlarının
genelinde sendromun var olduğu tespit edilmiş; özellikle beyin cerrahları,
genel cerrahlar ve kalp ve damar cerrahlarında hubris sendromu varlığı ortaya
çıkmıştır. Diğer sağlık meslek gruplarında ise; yapılan işin niteliği açısından
kendilerini hekime yakın hisseden gruplarda bu sendrom kendini göstermektedir.
ALGILANAN ÖRGÜTSEL DESTEĞİN, ÖRGÜTSEL BAĞLILIĞA ETKİSİNDE KİŞİLİK ÖZELLİKLERİNİN ROLÜ: OTEL İŞLETMELERİNDE BİR ARAŞTIRMA
Authors: ÖZKAN Çiğdem , BOZ Mustafa 
Published: July 2018

Bu
çalışmanın amacı; algılanan örgütsel destek ile örgütsel bağlılık arasındaki
ilişkide kişilik özelliklerinin rolünün ortaya çıkarılmasıdır. Bu amaca yönelik
olarak geçmiş çalışmalarla ilgili alan yazın taraması yapılmış ve kavramsal bir
araştırma modeli oluşturulmuştur. Kişilik özelliklerinin algılanan örgütsel
destek üzerinden örgütsel bağlığa etkisine yönelik sonuçlara göre;
“Dışadönüklük” kişilik özelliği algılanan örgütsel destek üzerinden “duygusal”
bağlılık üzerinde dolaylı etkiye sahip iken “Normatif” ve “Devam” bağlılığı
üzerinde etkiye sahip değildir. “Sorumluluk”, “Uyumluluk”, “Gelişime Açıklık”,
“Negatif Değerlilik” kişilik özellikleri algılanan örgütsel destek üzerinden
“Duygusal”, “Normatif” ve “Devam” bağlılıkları üzerinde dolaylı etkiye sahip
olduğu bulunmuştur. “Duygusal
Tutarsızlık” kişilik özelliği algılanan örgütsel destek üzerinden “Duygusal” ve
“Devam” bağlılığı üzerinde dolaylı etkiye sahip iken “Normatif” bağlılık
üzerinde dolaylı etkiye sahip bulunmamıştır. Özetle tüm kişilik boyutları
algılanan örgütsel destek üzerinden “Duygusal” bağlılık üzerinde dolaylı etkiye
sahip olduğu bulunmuştur.
Enemigo Suelo: Manzano Rewrites Cuban Romanticism
Authors: Price Rachel 
Published: July 2018

Este artículo rescata, desde la esclavitud, un contradiscurso del romanticismo. Se enfoca en cómo la poesía de Juan Francisco Manzano, escritor cubano y ex-esclavo, reescribe el afecto típico del romanticismo cubano. Para Manzano, es la esclavitud la que se interpone entre los amantes y la que engendra, lejos de una patria anhelada desde afuera, la fantasía de escaparse de la isla y de los terrores asociados con el terreno cubano. Por ende, este ensayo reflexiona más detenidamente sobre la figura - poética, jurídica y ecológica - del “suelo” en varias obras. En particular, se compara un poema de José María Heredia de 1835 con otro de Manzano, publicado en 1838, en el que éste parece retomar y resignificar unas palabras del primero:la frase de Heredia “Huyamos pues, este suelo delicioso” deviene en Manzano “Huyamos pues, ... nuestro enemigo suelo”. Como conclusión, el ensayo destaca las implicaciones de tal reescritura para repensar la ecología y el afecto durante el apogeo de la esclavitud cubana.
La construcción de la literatura mapuche
Authors: Carrasco Iván 
Published: July 2018

En este artículo se examina críticamente un aspecto de la llamada literatura mapuche de Chile: el proceso de su construcción en cuanto textualidad artística, mediante la interrelación colaborativa entre los autores mapuche con sus textos, la crítica literaria y la teoría en el contexto de las instituciones culturales.
El tratado médico-culinario como género de ficción en la narrativa hispanoamericana actual: Héctor Abad Faciolince y Mayra Santos-Febres
Authors: Climent-Espino Rafael 
Published: July 2018

Este ensayo ofrece, tomando como marco teórico la llamada gastrocrítica, un recorrido historicista por los tratados médico-culinarios clásicos y medievales para analizar la influencia de éstos en Tratado de culinaria para mujeres tristes de Héctor Abad Faciolince y en Tratado de medicina natural para hombres melancólicos de Mayra Santos-Febres. Se sitúa así a ambos escritores como evocadores o imitadores de la tradición secular del tratadismo médico y culinario haciendo énfasis en la necesidad de poner en relación periodos aparentemente inconexos para un análisis literario más provechoso. Palabras clave: gastrocrítica, tratadismo culinario, novela hispanoamericana Using the theoretical framework of gastrocriticism, this essay traces a historicist route through classic and medieval medical-culinary treatises to analyze their influence on Héctor Abad Faciolince’s Tratado de culinaria para mujeres tristes and Mayra Santos-Febres’ Tratado de medicina natural para hombres melancólicos. Both writers evoke or imitate the secular tradition of medical and culinary treatises; an analysis of these contemporary authors through the lens of works from an earlier era emphasizes the possibilities for literary criticism that identifies intersections of thought across various periods. Keywords: gastrocriticism, culinary treatises, Spanish American novel
Sentimental Objects: Nostalgia and the Child in Cinema of the Spanish Memory Boom
Authors: Thomas Sarah 
Published: July 2018

This article explores how two films from the so-called Spanish “memory boom” represent their child protagonists via a certain “anxiety of influence” in relation to their cinematic forebear El espíritu de la colmena (Erice, 1973 ). It argues that, despite their intertextual connection, these two more recent films differ from Erice’s in terms of their representation of childhood, making use of the child as an instrument of didacticism and nostalgia. In so doing, they offer an image of the child instrumentalized as object, rather than fully realized as subject.
Death as Volition: Suicide in the Early Azorín
Authors: Wood David W. 
Published: July 2018

La muerte en Azorín es una constante desde sus primeros relatos de fines del siglo XIX hasta sus obras más maduras de la década de los cuarenta. Este artículo analiza el suicidio en Buscapiés (1894 ), Bohemia (1897 ) y Diario de un enfermo (1901). Con la publicación de La voluntad en 1902 , los personajes desmuestran una voluntad insuficiente para suicidarse. En cambio, los personajes en obras anteriores manifiestan su determinación para escapar de situaciones insoportables por medio del suicidio. Demuestro que el suicidio es consecuencia de una decisión desesperada y de un conflicto entre palabras, escritura y existencia al que se enfrentan los protagonistasescritores de Bohemia y Diario de un enfermo . En el caso del político de Buscapiés consituye asimismo una clara condena del gobierno español de la Restauración.
Veil or Evil? Spotlighting Women Portrayal through Semiotics Analysis
Authors: Fata Ika Apriani 
Published: July 2018

The phenomenon of woman and man portrayal have been merely discussed world wide. Many viewpoints such as: media, politics, health, cultural studies, gender concerned on this topic. However, only a few of them was trying to seek out the language features attributed for women representation. Accordingly, to fill in this gap, this research aims at describing semiotical sign analysis of woman portrayal in media. A number of four corpus of Serambi Indonesia were analyzed based on two signification semiotics interpretations by Barthes (1967). The result eventually revealed that the language features attributed for women in the newspaper are woman as animal, as properties, as trigger of sins, as peaceful guard, those are considered as terms of denotative signification meaning. Meanwhile, the connotative meaning divided into two understandings; veil and evil, introducing positive and negative representation towards women. Finally it is expected that for further studies involve systemic functional linguistics or corpus linguistics towards other discourses as media to further develop the conclusions drawn from this present study.Keywords: Woman; Aceh; Semiotics; Portrayal
ANALYSIS OF DOMAIN SPECIFICITY OF THE PROTECTIVE CHIMERIC ANTIBODY ch14D5a AGAINST GLYCOPROTEIN E OF TICK-BORNE ENCEPHALITIS VIRUS
Authors: Baykov I. K. , Emelyanova L. A. , Sokolova L. M. , Karelina E. M. , Matveev A. L. , Babkin I. V. , Khlusevich Ya. А. , Podgornyy V. F. , Tikunova N. V. 
Published: July 2018

A drug for the prevention and therapy of tick-borne encephalitis virus is being developed on the basis of the protective chimeric antibody ch14D5a. At the same time, the epitope recognized by this antibody on the surface of glycoprotein E has not been localized yet. The aim of this work was to identify the domain of glycoprotein E, to which the protective antibody ch14D5a binds. As a result, four recombinant variants of glycoprotein E were generated using the bacterial expression system: (1) the rE protein containing the domains D1, D2, and D3 of glycoprotein E; (2) the rED1+2 protein containing domains D1 and D2; (3) the rED3_301 protein, which is domain D3 of glycoprotein E, and (4) the rED3_294 protein comprising domain D3 and a hinge region connecting domains D1 and D3. The rED3_294 and rED3_301 proteins were obtained in soluble monomeric form. The rE and rED1+2 proteins were extracted from the inclusion bodies of Escherichia coli. Using Western blot analysis and surface plasmon resonance analysis, it was demonstrated that the protective chimeric antibody ch14D5a and its Fab fragment bound specifically to domain D3 of glycoprotein E. Since the antibodies recognizing epitopes on the surface of domain D3 do not tend to cause antibody-dependent enhancement of the infection as compared to antibodies directed to domains D1 and D2, the data obtained confirm the promise of using the antibody ch14D5a in the development of a therapeutic preparation against the tick-borne encephalitis virus.
O Atlântico negro encontra o Oceano Índico: gerando novos paradigmas para um transnacionalismo do Sul Global – Perspectivas Literárias e Culturais
Authors: Hofmeyr Isabel 
Published: July 2018

Com a recente virada transnacional nas ciências humanas e sociais, as questões relacionadas ao translocalismo passaram a dominar a agenda acadêmica. Os estudos da África Austral orientados por perspetivas transnacionais basearam-se, geralmente, no modelo do Atlântico negro. Este artigo defende que é preciso complementar essa perspectiva com um engajamento sistemático com o Oceano Índico. O artigo descreve as principais tradições historiográficas associadas ao Oceano Índico, para realçar o modo como esses temas desafiam os pressupostos teorizados anteriormente com base no modelo do Atlântico negro. Na parte final do artigo, defende-se que a inclusão do Oceano Índico na cartografia da África do Sul ampliaria os mapas dos estudos culturais e literários desse país.
PENGGUNAAN KOMUNIKASI INSTRUKSIONAL OLEH PENDIDIK DI TAMAN PENDIDIKAN AL QUR’AN
Authors: April Ismaliza 
Published: July 2018

The general purpose of this research was to explore the utilization of instructional communication by the teachers in the Al Qur’an Education Institution. Specifically the research aimed at describing the use of instructional communication by the teachers based on verbal communication, non-verbal communication, and communication with media. The resultf of the research shows that the teachers of the Al Qur’an Education Institution of Husnul Khatimah has been using instructional communication properly. Eventhough, this research gives some suggestions to improve the teachers` competence in using the instructional communication.
MENUMBUHKAN MINAT MEMBACA SEBAGAI UPAYA PENINGKATAN MUTU TENAGA PENDIDIK PAUD DI INDONESIA
Authors: Surtiawati Cucu 
Published: July 2018

In this information and knowledge era, people tend to develop their expertise by obtaining information and knowledge as much as and as fast as possible. They will stand behind if they do not follow and adapt the advanced science and technology. Reading is a tool to obtain many kinds of information and reading habit is a precondition to build and develop reading society. However, reading has not become a habit aand reading interest is not high enough for most most of people in Indonesia. Reading skill and reading habit of the teachers of early childhood education are suspected unsatisfactory. This article discusses how to create reading interest and develop reading habit of the teachers of early childhood teachers as a means of improving their quality.
Bilateral Inferior Angle Ossicles of the Scapula: Pain Generators in a Young Woman
Authors: Gilde Alex K. , Henne Timothy D. 
Published: July 2018

Case:
We present the case of a 16-year-old woman with refractory shoulder pain despite nonoperative treatment. The only shoulder pathology that was noted on advanced imaging was an unfused ossicle on the inferior angle of each scapula. She was successfully treated with simple excision bilaterally; as demonstrated by the shoulder scores, there was substantial improvement.

Conclusion:
In young patients with vague and refractory shoulder pain with essentially normal radiographic findings, an ossicle on the inferior angle of the scapula may be considered a pain generator. Excision of the ossicle may provide excellent definitive treatment after more common shoulder pathology has been ruled out.
Knee Osteoarthritis with Chronic Quadriceps Tendon Rupture Treated with Total Knee Arthroplasty and Extensor Mechanism Allograft Reconstruction
Authors: Piatek Allison Z. , Lee Patrick , DeRogatis Michael J. , Boyajian David A. , Issack Paul S. 
Published: July 2018

Case:
A 51-year-old male construction worker with a history of chronic quadriceps tendon rupture presented with no active knee extension and tricompartmental knee osteoarthritis. He underwent simultaneous total knee arthroplasty and extensor mechanism allograft reconstruction. At 4 years postoperatively, the patient had pain-free knee function and active extension.

Conclusion:
The combination of a chronic quadriceps tendon rupture with lack of active knee extension and knee osteoarthritis is a rare and challenging problem. To our knowledge, this combined diagnosis and the treatment described in this case report have not been reported previously in the literature.
Biologic Therapies as Adjunctive Treatments in Rotator Cuff Repair
Authors: Mistry Jaydev , Henn R. Frank , Etcheson Jennifer I. , Gwam Chukwuweike U. , George Nicole E. , Delanois Ronald E. 
Published: July 2018

* The incidence of rotator cuff tears is on the rise; however, despite advancements in surgical techniques to augment repairs, failure rates continue to pose a challenge for orthopaedic surgeons.* A poor biologic environment is believed to be partly responsible for the inadequate tissue healing sometimes associated with rotator cuff tear repairs. Consequently, to provide the missing biologic component(s) required for adequate tendon repair, treatment strategies involving the use of adjunctive biologic therapies have been evaluated.* Biologic rotator cuff repair therapies—such as platelet-rich plasma (PRP), patches and scaffolds, mesenchymal stem cells (MSCs), and cytokines—have been investigated in both animal models and human clinical trials.* Biologic augmentation carries tremendous potential for improving rotator cuff healing, although the degree of short-term and long-term healing reported in the literature has varied.
From Static Spinal Alignment to Dynamic Body Balance: Utilizing Motion Analysis in Spinal Deformity Surgery
Authors: Diebo Bassel G. , Shah Neil V. , Pivec Robert , Naziri Qais , Patel Ashish , Post Nicholas H. , Assi Ayman , Godwin Ellen M. , Lafage Virginie , Schwab Frank J. , Paulino Carl B. 
Published: July 2018

* Three-dimensional motion analysis is necessary to bridge the gap between static spinal radiographic alignment and dynamic body balance in the setting of pediatric and adult spinal deformities.* Lessons learned from gait analysis in patients with adolescent idiopathic scoliosis may be applicable to patients with adult spinal deformity, with the potential to improve our understanding of dynamic compensatory mechanisms, the hip-spine complex, and proximal junctional kyphosis.* Dynamic and functional assessments such as gait analysis are expected to be the future of pediatric and adult spinal deformity research, with potential clinical and surgical applications.