bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge and beliefs about dietary inorganic nitrate in a representative sample of adults from the United Kingdom
Authors: Griffiths Alex , Grainger Evie , Matu Jamie , Alhulaefi Shatha , Whyte Eleanor , Hayes Eleanor , Brandt Kirsten , Mathers John C , Siervo Mario , Shannon Oliver M 
Published: October 2024

Abstract

Objective:
Evaluate knowledge and beliefs about dietary nitrate among United Kingdom (UK)-based adults.

Design:
An online questionnaire was administered to evaluate knowledge and beliefs about dietary nitrate. Overall knowledge of dietary nitrate was quantified using a twenty-one-point Nitrate Knowledge Index. Responses were compared between socio-demographic groups.

Setting:
UK.

Participants:
A nationally representative sample of 300 adults.

Results:
Only 19 % of participants had heard of dietary nitrate prior to completing the questionnaire. Most participants (∼70 %) were unsure about the effects of dietary nitrate on health parameters (e.g. blood pressure, cognitive function and cancer risk) or exercise performance. Most participants were unsure of the average population intake (78 %) and acceptable daily intake (83 %) of nitrate. Knowledge of dietary sources of nitrate was generally low, with only ∼30 % of participants correctly identifying foods with higher or lower nitrate contents. Almost none of the participants had deliberately purchased, or avoided purchasing, a food based around its nitrate content. Nitrate Knowledge Index scores were generally low (median (interquartile range (IQR)): 5 (8)), but were significantly higher in individuals who were currently employed v. unemployed (median (IQR): 5 (7) v. 4 (7); P < 0·001), in those with previous nutrition education v. no nutrition education (median (IQR): 6 (7) v. 4 (8); P = 0·012) and in individuals who had heard of nitrate prior to completing the questionnaire v. those who had not (median (IQR): 9 (8) v. 4 (7); P < 0·001).

Conclusions:
This study demonstrates low knowledge around dietary nitrate in UK-based adults. Greater education around dietary nitrate may be valuable to help individuals make more informed decisions about their consumption of this compound.
A Multiwavelength View of Black Holes and Outflows in Post-starburst Galaxies
Authors: Luo Yuanze 
Published: October 2024

Abstract. Post-starburst galaxies (PSBs) have quenched (significant decline in star formation rate) both recently and rapidly (≲Gyr). They are thus promising in providing insights into activities that are happening at the early stage of quenching. While studies have suggested that black hole feedback in the form of active galactic nuclei (AGN) and outflows play important roles in quenching, the details of how they impact the host galaxies and their interplay with other quenching mechanisms are still not fully understood. We find that PSBs commonly show signatures of AGN activity but they appear to be weak and/or heavily obscured. These AGN might be able to drive outflows but they are likely not strong enough to remove gas from the host galaxy. Direct evidence of AGN quenching the star formation of the host galaxy is still missing and AGN likely quench by disturbing rather than expelling the gas.
Intermediate mass black hole feedback in dwarf galaxy simulations with a resolved ISM and accurate nuclear stellar dynamics
Authors: Partmann Christian , Naab Thorsten , Lahén Natalia , Churazov Eugene , Hislop Jessica M. , Rantala Antti , Johansson Peter H. , Hirschmann Michaela 
Published: October 2024

AbstractRecent observations have established that dwarf galaxies can host black holes of intermediate mass (IMBH, 100Mȯ < MIMBH ≲ 105 Mȯ). With modern numerical models, we can test the growth of IMBHs as well as their evolutionary impact on the host galaxy. Our novel subsolar-mass (0.8 solar mass) resolution simulations of dwarf galaxies (M* = 2 × 107 Mȯ) have a resolved three-phase interstellar medium and account for non-equilibrium heating, cooling, and chemistry processes. The stellar initial mass function is fully sampled between 0.08–150 Mȯ while massive stars can form HII regions and explode as resolved supernovae. The stellar dynamics around the IMBH is integrated accurately with a regularization scheme. We present a viscous accretion disk model for the IMBH with momentum, energy, and mass conserving wind feedback. We demonstrate how the IMBH can grow from accretion of the cold and warm gas phase and how the presence of the IMBH and its feedback impacts the gas phase structure.
Testing AGN outflow and accretion models with SDSS quasar demographics
Authors: Temple Matthew J. 
Published: October 2024

AbstractOne commonly-invoked launching mechanism for AGN outflows is radiation line driving. This mechanism depends closely on the SED of the ionizing continuum, and so is inherently linked to the structure of the accretion flow. Theories of radiation line-driven winds therefore provide testable predictions as a function of black hole (BH) mass and accretion rate. In this work we confront these predictions using the ultraviolet emission line properties of 190,000 quasars from SDSS DR17. We quantify how the shape of CIV 1549Å and the equivalent width (EW) of HeII 1640Å depend on the BH mass and Eddington ratio inferred from MgII 2800Å. The blueshift of the CIV emission line is commonly interpreted as a tracer of quasar outflows, while the HeII EW traces the strength of the 10-100 eV continuum which photo-ionizes the ultraviolet emission line regions. Above L/LEdd > 0.2, there is a strong mass dependence in both CIV blueshift and HeII EW. Large CIV blueshifts are observed only in regions with both high BH mass and high accretion rate, consistent with predictions for radiation line driven winds. The observed trends in HeII and 2 keV X-ray strength are broadly consistent with theoretical models of AGN SEDs, where the ionizing SED depends on the accretion disc temperature and the strength of the soft excess. At L/LEdd < 0.2, we find a dramatic switch in behaviour: the ultraviolet emission properties show much weaker trends, and no longer agree with SED models, hinting at changes in the structure of the broad line region. Overall the observed emission line properties are generally consistent with the radiation line driving scenario, where quasar winds are governed by the SED, which itself results from the accretion flow and hence depends on both the SMBH mass and accretion rate.
Searching for outflows in X-ray weak quasars
Authors: Trefoloni Bartolomeo 
Published: October 2024

AbstractThe connection between X-ray weakness and powerful X-ray outflows is both expected in a scenario where outflows are connected with radiation-driven winds, and observed in several sources, both in the local Universe and at high redshift. Here I present the first results of a new study of this possible connection based on a search for SDSS quasars with weak X-ray emission in serendipitous XMM-Newton observations. The selected objects have a “normal” optical/UV blue continuum, but a flat and extraordinarily weak X-ray spectrum. The availability of rest-frame optical/UV spectra allows to check for the signature of outflows in the absorption lines and/or in the profiles of the emission lines. This method could reveal the presence of a population of so-far overlooked outflowing quasars and confirm the connection between winds and X-ray weakness in quasars.
AGN outflows and its variability
Authors: M Vivek , Nair Akhil , Mishra Sapna 
Published: October 2024

AbstractThe radiative mode of AGN feedback, operated through outflows, plays an essential role in the evolution of galaxies. Quasar outflows are detected as blue-shifted broad absorption lines in the UV/optical spectra of quasars. Thanks to the Sloan digital sky survey, 100,000 broad absorption line quasars are available now for ensemble statistical studies. This rich dataset has also enabled us to identify some peculiar cases of these sources. By quantifying the BAL fraction in radio-loud BAL quasars, our studies demonstrate a clear trend of increasing BAL fraction as the viewing angle approaches an edge-on orientation, favoring the orientation model of BAL quasars. Also, by contrasting the properties of BAL quasars with appearing and disappearing BAL troughs, our analysis suggests that the extreme variations in BAL troughs are driven by ionization changes.
Common Genetic Influence on the Relationship Between Gaming Addiction and Attention Deficit Hyperactivity Disorder in Young Adults: A Twin Study
Authors: Lee Seol-Ah , Hur Yoon-Mi 
Published: October 2024

AbstractAlthough the relationship between gaming addiction (GA) and attention deficit hyperactivity disorder (ADHD) is well established, the causal mechanism of this relationship remains ambiguous. We aimed to investigate whether common genetic and/or environmental factors explain the GA-ADHD relationship. We recruited 1413 South Korean adult twins (837 monozygotic [MZ], 326 same-sex dizygotic [DZ], and 250 opposite-sex DZ twins; mean age = 23.1 ± 2.8 years) who completed an online survey on GA and related traits. Correlational analysis and bivariate model-fitting analysis were conducted. Phenotypic correlation between GA and ADHD in the present sample was 0.55 (95% CI [0.51, 0.59]). Bivariate model-fitting analysis revealed that genetic variances were 69% (95% CI [64%, 73%]) and 68% (95% CI [63%, 72%]) for ADHD and GA respectively. The remaining variances (ADHD: 31%; GA: 32%) were associated with nonshared environmental variances, including measurement error. Genetic and nonshared environmental correlations between ADHD and GA were 0.68 (95% CI [0.62, 0.74]) and 0.22 (95% CI [0.13, 0.30]) respectively, which indicates that shared genes can explain 82% of the phenotypic correlation between ADHD and GA. Our study demonstrated that the ADHD-GA association was largely due to shared genetic vulnerability.
A Distinct Role for Aerosol and GHG Forcing in Historical CMIP6 Evapotranspiration Trends
Authors: Egli Marius , Humphrey Vincent , Sippel Sebastian , Knutti Reto 
Published: October 2024

AbstractEvapotranspiration (ET) is crucial for the global water balance, plant growth, and freshwater availability. It connects the surface water balance with surface energy fluxes, making its accurate representation vital for climate projections. However, global climate models (GCMs) struggle with ET representation due to resolution limitations and simplified depictions of soil, plant, and atmosphere interactions. Simulated future changes in ET are uncertain, and the role of driving processes remain unclear. Here, we explore the utility of a simple and interpretable method to disentangle these varying drivers. We investigate the sensitivity of JJA ET to different atmospheric variables through simple linear models predicting ET from atmospheric variables only. The model consistently yields good results across GCMs or forcing scenarios. We find that GCMs have shown strong decreases and subsequent increases in ET over the historical period, related to changes in net surface radiation. For future climate projections, decreases in water availability compete with higher available surface radiation, making future projections uncertain. Single forcing GCM realizations show that historical ET trends in densely populated regions have been more influenced by aerosol emissions than greenhouse gases. Finally, we investigate which atmospheric variables explain most short‐term (year‐to‐year) and long‐term (decadal) changes. While water availability may be the most important driver of short‐term variability, for certain regions, radiation trends dominate long‐term forcing. This paper leverages a simple approach to provide a comprehensive and understandable view into recent and future changes in ET, reconciling the evidence provided by more complex case studies.
Electron Temperatures in the Venusian Ionosphere From Parker Solar Probe Using Quasi‐Thermal Noise Spectroscopy
Authors: Tannous Speero M. , Bonnell John W. , Pulupa Marc , Bale Stuart D. 
Published: October 2024

AbstractParker Solar Probe (PSP) uses Venus gravity assists (VGA) to achieve the closest orbits to the Sun by a spacecraft. During the third (VGA3) and fourth (VGA4) Venus gravity assists, the PSP entered the Venusian ionosphere. The core electrons could not be detected as they were below the SWEAP/SPAN electrostatic analyzer instrument energy threshold. However, there is another way to estimate the core temperature using quasi‐thermal noise (QTN) data measured by the PSP/FIELDS Radio Frequency Spectrometer instrument. QTN spectroscopy offers an effective tool for measuring electron temperature and density when the electrons are too cold for other instruments to measure, as is the case with VGA3 and VGA4. Low‐frequency plasma wave data from the closest approach during VGA3 and VGA4 was analyzed with the QTN spectroscopy technique to determine the density and first‐ever in‐situ thermal electron temperature of the Venusian ionosphere at solar minimum.
The Unique Behavior of Vertical Velocity in Developing Deep Convection
Authors: Kurowski Marcin J. , Paris Andrea , Teixeira Joao 
Published: October 2024

AbstractWhen daytime tropical convection develops away from mesoscale disturbances, it typically transitions gradually from dry to shallow to deep convection on hourly timescales. The transition is commonly associated with the formation of larger horizontal boundary‐layer structures and an increasing level of cloud organization aloft. This study demonstrates that a spectral analysis of the resolved high‐resolution sub‐cloud flow features allows for a robust identification of dominant length scales and the quantification of their growth rates during the transition. Furthermore, it is shown that temperature, moisture, and horizontal winds develop multiple length scales with the largest ones growing up to several kilometers in magnitude. However, the vertical velocity behaves in a distinct manner developing significantly smaller values, comparable over land and ocean. This indicates stronger inherent limits of vertical velocity to self‐organize by size.
Centennial‐Scale Variability of the Atlantic Meridional Overturning Circulation in CMIP6 Models Shaped by Arctic–North Atlantic Interactions and Sea Ice Biases
Authors: Mehling Oliver , Bellomo Katinka , von Hardenberg Jost 
Published: October 2024

AbstractClimate variability on centennial timescales has often been linked to internal variability of the Atlantic Meridional Overturning Circulation (AMOC). However, due to the scarceness of suitable paleoclimate proxies and long climate model simulations, large uncertainties remain on the magnitude and physical mechanisms driving centennial‐scale AMOC variability. For these reasons, we perform a systematic multi‐model comparison of centennial‐scale AMOC variability in pre‐industrial control simulations of state‐of‐the‐art global climate models. Six out of nine models in this study exhibit a statistically significant mode of centennial‐scale AMOC variability. Our results show that freshwater exchanges between the Arctic Ocean and the North Atlantic provide a plausible driving mechanism in a subset of models, and that AMOC variability can be amplified by ocean–sea ice feedbacks in the Labrador Sea. The amplifying mechanism is linked to sea ice cover biases, which could provide an observational constraint for centennial‐scale AMOC variability.
Observations of Sea Ice Edge Position in the Barents and Greenland Seas: Temporal Variability and Long‐Term Changes
Authors: Masunaga R. , Komuro Y. , Kawasaki T. , Ono J. 
Published: October 2024

AbstractSea ice edges play an essential role in the Earth's climate and weather systems through active atmosphere‐ice‐ocean interactions. However, our understanding of the observed positions of sea ice edges remains limited. The present study investigated, on seasonal and longer timescales from 1979 to 2023, the variability in sea ice edge positions in the Barents and Greenland Seas. We objectively derived the positions of sea ice edges based on satellite‐derived sea ice concentration gridded on a 25‐km resolution. In the Barents Sea, warm, narrow currents flow eastward along the northern and southern rims of the Central Bank. Until the mid‐2000s, sea ice edges fluctuated between these currents interannually during December–June, depending on the surface wind direction. However, after the mid‐2000s, the sea ice edges were mostly positioned near the northern current or farther to the north. Furthermore, sea ice edges during October–March were identified frequently near the warm current flowing along the continental slope in the northern Barents Sea after the mid‐2000s. In the Greenland Sea, sea ice edges were typically positioned near the East Greenland Current (EGC) throughout the year until 2006. However, sea ice edges in summer were located far to the west of the EGC after 2006. These observations suggest that the geographical relationship between sea ice edges and ocean currents has changed due to global warming.
A burden of rare copy number variants in obsessive-compulsive disorder
Authors: Halvorsen Matthew W. , de Schipper Elles , Bäckman Julia , Strom Nora I. , Hagen Kristen ,   Nordic OCD and Related Disorders Consortium (NORDiC), Chen Long Long , Djurfeldt Diana R. , Höffler Kira D. , Kähler Anna K. , Lichtenstein Paul , Morrill Kathleen , Noh Hyun Ji , Eide Thorstein Olsen , Zayats Tetyana , Lindblad-Toh Kerstin , Karlsson Elinor K. , Pedersen Nancy L. , Wallert John , Bulik Cynthia M. , Fundín Bengt , Landén Mikael , Kvale Gerd , Hansen Bjarne , Haavik Jan , Mattheisen Manuel , Rück Christian , Mataix-Cols David , Crowley James J. 
Published: October 2024

AbstractCurrent genetic research on obsessive-compulsive disorder (OCD) supports contributions to risk specifically from common single nucleotide variants (SNVs), along with rare coding SNVs and small insertion-deletions (indels). The contribution to OCD risk from rare copy number variants (CNVs), however, has not been formally assessed at a similar scale. Here we describe an analysis of rare CNVs called from genotype array data in 2248 deeply phenotyped OCD cases and 3608 unaffected controls from Sweden and Norway. Cases carry an elevated burden of CNVs ≥30 kb in size (OR = 1.12, P = 1.77 × 10−3). The excess rate of these CNVs in cases versus controls was around 0.07 (95% CI 0.02–0.11, P = 2.58 × 10−3). This signal was largely driven by CNVs overlapping protein-coding regions (OR = 1.19, P = 3.08 × 10−4), particularly deletions impacting loss-of-function intolerant genes (pLI >0.995, OR = 4.12, P = 2.54 × 10−5). We did not identify any specific locus where CNV burden was associated with OCD case status at genome-wide significance, but we noted non-random recurrence of CNV deletions in cases (permutation P = 2.60 × 10−3). In cases where sufficient clinical data were available (n = 1612) we found that carriers of neurodevelopmental duplications were more likely to have comorbid autism (P < 0.001), and that carriers of deletions overlapping neurodevelopmental genes had lower treatment response (P = 0.02). The results demonstrate a contribution of rare CNVs to OCD risk, and suggest that studies of rare coding variation in OCD would have increased power to identify risk genes if this class of variation were incorporated into formal tests.
The mechanisms behind heatstroke-induced intestinal damage
Authors: Sun Minshu , Li Qin , Zou Zhimin , Liu Jian , Gu Zhengtao , Li Li 
Published: October 2024

AbstractWith the frequent occurrence of heatwaves, heatstroke (HS) is expected to become one of the main causes of global death. Being a multi-organized disease, HS can result in circulatory disturbance and systemic inflammatory response, with the gastrointestinal tract being one of the primary organs affected. Intestinal damage plays an initiating and promoting role in HS. Multiple pathways result in damage to the integrity of the intestinal epithelial barrier due to heat stress and hypoxia brought on by blood distribution. This usually leads to intestinal leakage as well as the infiltration and metastasis of toxins and pathogenic bacteria in the intestinal cavity, which will eventually cause inflammation in the whole body. A large number of studies have shown that intestinal damage after HS involves the body’s stress response, disruption of oxidative balance, disorder of tight junction proteins, massive cell death, and microbial imbalance. Based on these damage mechanisms, protecting the intestinal barrier and regulating the body’s inflammatory and immune responses are effective treatment strategies. To better understand the pathophysiology of this complex process, this review aims to outline the potential processes and possible therapeutic strategies for intestinal damage after HS in recent years.
Y chromosome sequencing data suggest dual paths of haplogroup N1a1 into Finland
Authors: Preussner Annina , Leinonen Jaakko , Riikonen Juha , Pirinen Matti , Tukiainen Taru 
Published: October 2024

AbstractThe paternally inherited Y chromosome is highly informative of genetic ancestry, therefore making it useful in studies of population history. In Finland, two Y-chromosomal haplogroups reveal the major substructure of the population: N1a1 enriched in the northeast and I1a in the southwest, suggested to reflect eastern and western ancestry contributions to the population. Yet, beyond these major Y-chromosomal lineages, the distribution of finer-scale Y-chromosomal variation has not been assessed in Finland. Here, we provide the most comprehensive Y-chromosomal study among the Finns to date, exploiting sequences for 1802 geographically mapped Finnish Y chromosomes from the FINRISK project. We assessed the distribution of common Y-chromosomal haplogroups (frequency ≥1%) throughout 19 Finnish regions and compared the autosomal genetic backgrounds of the Y-chromosomal haplogroups. With such high-resolution data, we were able to find previously unreported sublineages and resolve phylogenetic relationships within haplogroups N1a1 (64%), I1a (25%), R1a (4.3%), and R1b (4.8%). We further find novel geographical enrichment patterns among these Y-chromosomal haplogroups, most notably observed for haplogroup N1a1 dividing into two lineages with differing distributions. While sublineage N-Z1934 (42%) followed a northeastern enrichment pattern observed for all N1a1 carriers in general, sublineage N-VL29 (22%) displayed an enrichment in the southwest. Further, the carriers of N-VL29 showed a higher proportion of southwestern autosomal ancestry compared to carriers of N-Z1934. Collectively, these results point to distinct demographics within haplogroup N1a1, possibly induced by two distinct arrival routes into Finland. Overall, our study suggests a more complex genetic population history for Finns than previously proposed.