bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Personal Video Technology for Teaching and Assessment of Surgical Skills
Authors: Sheahan Guy , Reznick Richard , Klinger Don , Flynn Leslie , Zevin Boris 
Published: May 2019

ABSTRACT

Background
Improvements in personal technology have made video recording for teaching and assessment of surgical skills possible.

Objective
This study compared 5 personal video-recording devices based on their utility (image quality, hardware, mounting options, and accessibility) in recording open surgical procedures.

Methods
Open procedures in a simulated setting were recorded using smartphones and tablets (MOB), laptops (LAP), sports cameras such as GoPro (SC), single-lens reflex cameras (DSLR), and spy camera glasses (SPY). Utility was rated by consensus between 2 investigators trained in observation of technology using a 5-point Likert scale (1, poor, to 5, excellent).

Results
A total of 150 hours of muted video were reviewed with a minimum 1 hour for each device. Image quality was good (3.8) across all devices, although this was influenced by the device-mounting requirements (4.2) and its proximity to the area of interest. Device hardware (battery life and storage capacity) was problematic for long procedures (3.8). Availability of devices was high (4.2).

Conclusions
Personal video-recording technology can be used for assessment and teaching of open surgical skills. DSLR and SC provide the best images. DSLR provides the best zoom capability from an offset position, while SC can be placed closer to the operative field without impairing sterility. Laptops provide best overall utility for long procedures due to video file size. All devices require stable recording platforms (eg, bench space, dedicated mounting accessories). Head harnesses (SC, SPY) provide opportunities for “point-of-view” recordings. MOB and LAP can be used for multiple concurrent recordings.
Carbono y nitrógeno del suelo en los sistemas bosque mesófilo de montaña, agroforestal y monocultivo de café
Authors: Cristóbal-Acevedo David , Tinoco-Rueda Juan A. , Prado-Hernández Jorge Victor , Hernández-Acosta Elizabeth 
Published: May 2019

Introducción: En los sistemas naturales y agroecosistemas, el estudio del carbono y nitrógeno del suelo como función del tipo y magnitud de su cubierta vegetal es importante debido a que la concentración y contenido de dichos elementos tienen relación con la fertilidad, calidad de los suelos e impacto ambiental.
Objetivos: Determinar el carbono y nitrógeno en el suelo como función del tipo y magnitud de la cubierta vegetal de los sistemas bosque mesófilo de montaña (BMM), monocultivo de café a pleno sol (MCPS), sistema agroforestal de café como policultivo tradicional (AFCPT) y sistema agroforestal de café como policultivo comercial (AFCPC).
Materiales y métodos: Las cubiertas vegetales se caracterizaron y cuantificaron. Se tomaron muestras de suelo a las profundidades 0 a 10, 10 a 20 y 20 a 30 cm, para determinar las concentraciones y contenidos de carbono orgánico del suelo (COS) y nitrógeno en sus formas total (Nt), orgánico (Norg), nitratos (NO3-), amonio (NH4+) y mineral (Nmin).
Resultados y discusión: El orden de magnitud de las cubiertas vegetales fue BMM>AFCPT>AFCPC>MCPS. Este mismo orden se tuvo en los almacenamientos de COS (BMM: 229.33 Mg·ha-1, AFCPT: 211.03 Mg·ha-1, AFCPC: 90.95 Mg·ha-1 y MCPS: 92.56 Mg·ha-1), Nt (BMM: 16.10 Mg·ha-1, AFCPT:14.21 Mg·ha-1, AFCPC: 7.89 Mg·ha-1 y MCPS: 6.50 Mg·ha-1) y Norg (BMM: 16.02 Mg·ha-1, AFCPT:14.16 Mg·ha-1, AFCPC: 7.82 Mg·ha-1 y MCPS: 6.44 Mg·ha-1). La relación C:N fue similar en los sistemas.
Conclusiones: El BMM y AFCPT presentaron los mayores almacenamientos de COS y Nt en el suelo. Los sistemas agroforestales con café fueron mejores que el monocultivo de café.
Increasing of selenium content and qualitative parameters in tomato (Lycopersicon esculentum Mill.) after its foliar application
Authors: Andrejiová Alena , Hegedűsová Alžbeta , Adamec Samuel , Hegedűs Ondrej , Mezeyová Ivana 
Published: May 2019

The effect of genotype and selenium foliar biofortification in the form of an aqueous solution of sodium selenate on the content of total carotenoids, vitamin C, total polyphenols and selenium content in the tomato fruits was studied. Field experiment was held in the Botanical garden of the Slovak University of Agriculture in 2016. Seven determinant varieties of tomato in the two variants were observed. The results of experiments show that treatment of plants with the dose of Se concentration (150 g Se.ha-1) at the flowering stage significantly increased the total Se content in the in tomato fruits. Foliar application of selenium had a positive effect on the increase of total polyphenol. The influence of Se biofortification on the content of vitamin C and carotenoids was not detected. Selenium foliar fertilization in dosage 150 g.ha-1 is suitable way of tomato fruits enriching in polyphenols, without negative effect on other antioxidants content.
Language Performing Violence and Violence Performed on Language: A Political Lesson in Harold Pinter's One for the Road, Mountain Language, The New World Order, and The Pres and an Officer
Authors: Saunders Judith 
Published: May 2019

Abstract
In the context of today's political rhetoric, this article invites discussion of a subset of Harold Pinter's more explicitly political plays, including his recently discovered sketch, The Pres and an Officer. The plays demonstrate how language can be used to inflict violence and how, in the process, language itself is abused. Paucity of language implies paucity of thought and, as Pinter so succinctly warns us, poses a threat to civil discourse and the democracy that depends on it. The article draws parallels between Pinter's exposé of the role that language plays in the workings of totalitarian regimes and the effect of Trump's use of language in today's political discourse. In this light, it argues Pinter's plays call for political praxis.
Experiences of School as a Mediator between Interpersonal Competence and Happiness in Adolescents
Authors: Baytemir Kemal 
Published: May 2019

The main purpose of this research is to examine the mediating role of the perception of school experiences in the relationship between interpersonal competence and happiness in adolescent. The participants in the study consisted of a total of 268 students, 104 females (39%) and 164 males (61%), attending various high schools in a city in the mid-Black Sea region. The participating students’ ages ranged between 14 and 18, with an average age of 16.22 (SD = 1.2). In order to gather data the “Interpersonal Competence Scale”, “Perceived School Experience Scale ” and “Oxford Happiness Scale” were used as measures. According to the results of the research, interpersonal competence predicts perceptions of school experience and happiness, perception of school experience predicts happiness. Analysis by structural equation modeling revealed that the perception of school experience has a partial mediating role in relationship between interpersonal competence and happiness in adolescents. The research findings are discussed within the context of the related literature and some suggestions are provided for researchers and practitioners in the field of mental health.
Clarifying the two facets of Self-Oriented Perfectionism: influences on affect and the Big Five traits of personality in children
Authors: Vicent María , Inglés Cándido J. , Sanmartín Ricardo , Gonzálvez Carolina , Aparicio-Flores María del Pilar , García-Fernández José Manuel 
Published: May 2019

This study analyses the relationship between the perfectionism dimensions, i.e. Self-Oriented Perfectionism-Critical (SOP-C) and Self-Oriented Perfectionism-Striving (SOP-S), and affect and the Big Five traits of personality in a sample of 804 Spanish students aged 8 to 11 (M = 9.57; DE = 1.12). Student’s t test, Cohen’s d index and logistic regression analysis were used. The high SOP-C group scored significantly higher than their peers having low SOP-C on Negative Affect and Neuroticism, and lower on Positive Affect, Agreeableness, Consciousness and Openness to Experience. To the contrary, students with high SOP-S scored significantly higher on all adaptive dimensions (i.e. Positive Affect, Extraversion, Agreeableness, Consciousness and Openness to Experience), and lower on Negative Affect and Neuroticism. Effect sizes were small for most of statistically significant differences. These findings were also supported by regression analysis. Results are discussed in light of the debate on the adaptive or maladaptive nature of Self-Oriented Perfectionism.
« Une loi, une foi, un roi » : tolérance et concorde en Nouvelle-France à l’époque d’Henri IV*
Authors: De Waele Michel 
Published: May 2019

L’arrivée des Européens en Amérique les expose aux populations locales et à l’attitude qu’il leur fallait adopter face à elles. Les Français, lorsqu’ils abordèrent les rives de l’Acadie et du Saint-Laurent, adoptèrent logiquement la politique qui avait permis à leur roi de calmer les troubles qui avaient secoué le royaume durant la seconde moitié du XVIe siècle : la tolérance provisoire des différences – un mal nécessaire – devait mener à la concorde, c’est-à-dire à l’unité sous une seule loi, une seule foi et un seul roi de l’ensemble des habitants du territoire, indigènes comme non-indigènes. La première partie de cet article explique la différence qui existait à cette époque entre tolérance et concorde et expose comment la première était un moyen, et non un objectif, permettant d’atteindre des buts politiques, religieux ou économiques précis. La deuxième partie analyse comment la politique royale s’est transposée en Nouvelle-France sous le règne d’Henri IV.
Crítica e coalizão: repensar a resistência com Foucault e Butler
Authors: Duarte André , César Maria Rita de Assis 
Published: May 2019

Discutimos a importância e o significado de algumas noções-chave do pensamento de Michel Foucault e de Judith Butler, como as noções de “atitude crítica” e de “políticas de coalizão”, tendo em vista repensar o estatuto da noção e da própria prática da resistência, no contexto das lutas dos movimentos sociais de caráter identitário, vinculadas às demandas de populações marginalizadas (pessoas negras; mulheres; LGBTs). Essa discussão nos permite estabelecer uma relação entre a crítica e a resistência no pensamento de Foucault, bem como nos permite relacionar estes aspectos centrais do pensamento foucaultiano à reflexão política pós-identitária de Judith Butler. Por sua vez, a associação de noções de crítica, resistência e políticas de coalizão nos permite propor uma avaliação crítica dos embates fratricidas entre militantes de diversos movimentos sociais, cuja ênfase em concepções identitárias rígidas tem promovido o enfraquecimento dos próprios sujeitos da resistência.
Genetic Expression of Different Coat Colour Variants of Black Bengal Goat (BBG) in Bangladesh
Authors: Habib Md Ahsan , Akhtar Ambia , Bhuiyan Abul Kashem Fazlul Haque , Afroz Most Farhana 
Published: May 2019

Aims: To investigate the genetic expression of different coat colour variants in Black Bengal Goat (BBG) of Bangladesh.
Study Design: CRD with non-orthogonal hierarchy.
Place and Duration of Study: This study was carried out at 3 rural village communities of Bhaluka Upazila in Mymensingh district of Bangladesh from 2009 to 2013.
Methodology: All goats in community breeding program under this study were ear-tagged and maintained under semi-intensive management system with three breeding strategies in progressive generations. Data were collected from a baseline survey for goat population study along with 3 progressive generations produced from the community foundation flocks. The colour distribution and the colours of kids from matings among different colour parents were observed and recorded accordingly. The recorded data were analyzed by "SPSS 20.0" statistical program.
Results: The highest colour populations of about 53% were solid black in colour and others being Bezoar (31%), black with Toggenbergpattern (9%), black with Dutch belt pattern (6%) and solid brown (only 0.5%). Sex and generation had no significant effect on coat colour expression, while, coat colour in different locations differed significantly. For the analysis of coat colour inheritance, two categories of offspring were considered in this study; one from known coat colour dams mated with unknown coat colour sire and another from known coat colour parents. In the earlier category, most of the offspring exposed their dam’s coat colour when mated to unknown coat colour sires. For later category, there were varieties of coat colours offspring, produced from matings between two different or same colour parents.
Conclusion: Although the segregation of coat colours among offspring showed dominance of parents` colour, there were also offspring`s other than parents` coat colours. This might be due to polymorphism of coat colour gene in BBG.
Metronomic Low Dose Leucovorin- Fluorouracil versus Supportive Treatment for Patients with Recurrent or Metastatic Colorectal Cancer
Authors: Rashed Elkalla Hend M. Hamdey , Elzahy Mohamed Saad , Elazab Shoukri Hassan 
Published: May 2019

Introduction: There was an improvement in therapeutic regimens for advanced colorectal cancer (CRC) in the last few decades. The low dose metronomic palliative chemotherapy in patients with advanced CRC after the failure of standard chemotherapy led to a dramatic increase in efficacy, reduction of mortality rates, and improves survival in the form of control symptoms, and enhances or improves quality of life which is an important issue in that group of patients.
Patients and Methods: We include 60 Patients with recurrent or metastatic colorectal cancer after failure of multiple lines of chemotherapy. The patients were randomized in two groups either to receive supportive treatment in group A (30 patients) or low dose weekly leucovorin 20 mg/m² plus 5-flourouracil 425 mg/m² for 3 weeks and 1 week rest in group B (30 patients). Patients in group B received palliative chemotherapy for 4 months at least.
Results: After a follow up period of 19 months, the mean time to progression (TTP) is 4.9 months for the group (A) but is higher in group (B) as it is 7.8 months and it shows a statistically significant difference (P value <0.001). Also, the mean overall survival(OS) is 15.3 months for group (A) and 18.8 months for group (B) and this is statistically significant (P value <0.002). No grade 3 or 4 toxicity was detected. After 4 months of the study, 29 patients (96.6%) still have the stable disease compared to 18 patients (60%) of group (A). After 8 months, only 12 patients (40%) of group (B) show stable disease while all patients of group (A) have disease progression.
Conclusion: We conclude that metronomic weekly leucovorin-5 FU could provide a good tolerable way to go on with chemotherapy treatment while at the same time not have major threatening side effects.
Scn1b deletion in adult mice results in seizures and SUDEP
Authors: O'Malley Heather A. , Hull Jacob M. , Clawson Brittany C. , Chen Chunling , Owens‐Fiestan Gic , Jameson Margaret B. , Aton Sara J. , Parent Jack M. , Isom Lori L. 
Published: May 2019

AbstractPathogenic loss‐of‐function variants in SCN1B are linked to Dravet syndrome (DS). Previous work suggested that neuronal pathfinding defects underlie epileptogenesis and SUDEP in the Scn1b null mouse model of DS. We tested this hypothesis by inducing Scn1b deletion in adult mice that had developed normally. Epilepsy and SUDEP, which occur by postnatal day 21 in Scn1b null animals, were observed within 20 days of induced Scn1b deletion in adult mice, suggesting that epileptogenesis in SCN1B‐DS does not result from defective brain development. Thus, the developmental brain defects observed previously in Scn1b null mice may model other co‐morbidities of DS.
Whole Cell‐Based Cascade Biotransformation for the Production of (S)‐Mandelic Acid from Styrene, L‐Phenylalanine, Glucose, or Glycerol
Authors: Lukito Benedict Ryan , Sekar Balaji Sundara , Wu Shuke , Li Zhi 
Published: May 2019

Abstract(S)‐Mandelic acid is a useful and high value chemical with many synthetic applications, but its synthesis often requires the use of toxic cyanide. Here, we report the development of several cyanide‐free methods to prepare (S)‐mandelic acid via cascade biotransformation. Enhanced production of (S)‐mandelic acid from styrene via 4‐step enzyme cascades was achieved with Escherichia coli (A‐M1_R‐M2) cells, giving 118–144 mM (18–21.9 g/L, 72–79% yield) product. The process was scaled up to 1.5 L to produce 140 mM (21.3 g/L) of (S)‐mandelic acid in 70% yield. A strategy with the recycling and reuse of Escherichia coli cells, unreacted substrate, and organic solvent was developed to enhance the productivity of (S)‐mandelic acid through repeated batches, affording 190 mM (95% yield) and 328 mM (82% yield) product in two and four batches, respectively. (S)‐mandelic acid was also produced from bio‐derived L‐phenylalanine via 6‐step enzyme cascades. Biotransformation of L‐phenylalanine with Escherichia coli (LZ37) cells expressing all enzymes for the reactions gave 160 mM (S)‐mandelic acid in 80% yield. Moreover, (S)‐mandelic acid were synthesized from glycerol or glucose via L‐phenylalanine biosynthesis pathway and the 6‐step enzyme cascade. Coupling of Escherichia coli (NST74‐Phe) with Escherichia coli (LZ37) enabled the sustainable production of 63 mM (10 g/L) or 52 mM (8 g/L) (S)‐mandelic acid from renewable feedstocks glycerol and glucose, respectively.magnified image
Who has the guts to deprescribe proton pump inhibitors? A pharmacist‐led intervention in a long‐term care facility setting
Authors: Tandun Rachel , Bubbar Carolyn , Tejani Aaron M. 
Published: May 2019

AbstractObjectiveLong‐term use of proton pump inhibitors (PPIs) has been associated with an increased risk of harm. There are few studies evaluating pharmacist‐led PPI deprescribing interventions within a long‐term care facility setting. The aim of this study was to describe the changes and influencing factors seen with a pharmacist‐led PPI deprescribing intervention in two Fraser Health Authority long‐term care facilities in British Columbia.MethodsThis 4‐month intervention involved lists of residents who had active PPI orders being handed out to physicians from two facilities. The pharmacist conducted weekly reviews of residents from Facility 1 and offered deprescribing recommendations. The number and methods of PPI deprescribing orders per facility were determined after the intervention.ResultsOut of 58 residents from the two facilities, 30 (62.5%) had a deprescribing order. Facility 1 had 83.3% (20/24) of residents with a PPI deprescribing order, in contrast to 41.7% (10/24) from Facility 2. Overall, 80.0% of residents had successfully completed PPI deprescribing orders by the end of the study period.ConclusionClinical pharmacist intervention may increase the rate of initiation in PPI deprescribing orders within a long‐term care facility setting. Factors that influence success include intervention timing, active collaboration, having residents under direct care, and clear documentation of PPI indications.
The first case report of medulloblastoma associated with Tatton‐Brown–Rahman syndrome
Authors: Sweeney Kieron J. , Mottolese Carmine , Belot Alexandre , Szathmari Alexandru , Frappaz Didier , Lesca Gaetan , Putoux Audrey , Di Rocco Federico 
Published: May 2019

AbstractDNMT3A codes for a DNA methyl transferase enzyme that plays a central role embryogenesis. Somatic mutations in this gene have been associated with tumorigenesis and are associated with a number of cancers. The recently described Tatton‐Brown–Rahman syndrome (TBRS) is due to heterozygous germline mutations in the DNMT3A gene. So far, only one case of hematological malignancy associated with TBRS have been reported. Here, we describe the first case presenting with TBRS and medulloblastoma. We also discuss the associations between mutations in DNMT3A found in TBRS, AML, and medulloblastoma.
Redox/pH Dual Stimuli‐Responsive Acridine Spiropyran
Authors: Hirao Yasukazu , Taniguchi Toshiaki , Teraoka Mitsuru , Kubo Takashi 
Published: May 2019

AbstractA spiropyran derivative containing an acridinium and a phenoxide moieties was found to exhibit both halochromism and electrochromism in response to acid stimulation and oxidative stimulation, respectively. Variable scan‐rate voltammetric studies revealed that the acridine spiropyran undergoes a reversible conversion between a closed‐ring and an open‐ring form during the redox cycle. The presence of a ring‐opened radical cation species was demonstrated by simultaneous electrochemical ESR measurements.
A strategy for improving the prognosis of non‐occlusive mesenteric ischemia (NOMI): a single‐center observational study
Authors: Nakamura Fumiko , Yui Rintaro , Muratsu Arisa , Onoe Atsunori , Nakajima Mari , Takahashi Hiroki , Kishimoto Masanobu , Sakuramoto Kazuhito , Muroya Takashi , Kajino Kentaro , Ikegawa Hitoshi , Kuwagata Yasuyuki 
Published: May 2019

AimThe purpose of this study was to determine the prognostic factors of non‐occlusive mesenteric ischemia (NOMI) and to examine treatment strategies that could improve its prognosis.MethodsWe retrospectively identified 30 patients who underwent emergency laparotomy for NOMI in Kansai Medical University Hospital (Hirakata, Japan) from April 2013 to December 2017. We examined prognostic factors related to discharge outcome and also examined the prognostic impact of open abdominal management and second look operation strategy (OSS) by dividing the patients into the non‐OSS group and the OSS group.ResultsThe primary end‐point was a prognostic factor for outcome at discharge of the 30 patients. The outcome at discharge was compared between the survival group and the death group. Multivariate analysis was undertaken on two items from the univariate analysis that showed a significant difference (computed tomography findings of intestinal pneumatosis and acute disseminated intravascular coagulation [DIC] score). As a result, there was a significant difference in the factors of intestinal pneumatosis (odds ratio = 0.054; 95% confidence interval, 0.005–0.607; P = 0.018) and DIC score (odds ratio = 1.892; 95% confidence interval, 1.077–3.323; P = 0.027). The secondary end‐point was the treatment outcome before and after the application of OSS. Operation time was significantly shorter and the amount of bleeding was also significantly less in the OSS group.ConclusionComputed tomography findings of intestinal pneumatosis and the acute disseminated intravascular coagulation score were found to be prognostic factors for survival in patients with NOMI. Aggressive laparotomy to determine the definitive diagnosis is needed and OSS could be useful to improve patient prognosis for survival from NOMI.