bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metal–Organic Framework Hybrid‐Assisted Formation of Co3O4/Co‐Fe Oxide Double‐Shelled Nanoboxes for Enhanced Oxygen Evolution
Authors: Wang Xiao , Yu Le , Guan Bu Yuan , Song Shuyan , Lou Xiong Wen (David) 
Published: May 2018

AbstractRational design of complex metal–organic framework (MOF) hybrid precursors offers a great opportunity to construct various functional nanostructures. Here, a novel MOF‐hybrid‐assisted strategy to synthesize Co3O4/Co‐Fe oxide double‐shelled nanoboxes is reported. In the first step, zeolitic imidazolate framework‐67 (ZIF‐67, a Co‐based MOF)/Co‐Fe Prussian blue analogue (PBA) yolk–shell nanocubes are formed via a facile anion‐exchange reaction between ZIF‐67 nanocube precursors and [Fe(CN)6]3− ions at room temperature. Subsequently, an annealing treatment is applied to prepare Co3O4/Co‐Fe oxide double‐shelled nanoboxes. Owing to the structural and compositional benefits, the as‐derived Co3O4/Co‐Fe oxide double‐shelled nanoboxes exhibit enhanced electrocatalytic performance for oxygen evolution reaction in alkaline solution.
MOF‐Derived Vertically Aligned Mesoporous Co3O4 Nanowires for Ultrahigh Capacity Lithium‐Ion Batteries Anodes
Authors: Ma Yuanyuan , He Jiating , Kou Zongkui , Elshahawy Abdelnaby M. , Hu Yating , Guan Cao , Li Xu , Wang John 
Published: May 2018

AbstractSelf‐supported mesoporous nanowire (NW) arrays grown directly on a current‐collector substrate represent an attractive nanoarchitecture for highly active electrodes in lithium‐ion batteries (LIBs). However, few reports have addressed the concern for a rational design of such an advanced material construction, where it is still rather difficult to establish the key parameters, especially by the conventional synthesis procedure. In this work, the vertically aligned Co3O4 mesoporous nanowires grown on Ni foam (denoted as CONWs/NF) are prepared after facile pyrolysis (350 °C) of 1D nanowire‐like metal–organic frameworks (MOFs). The MOF‐derived 1D mesoporous structure can provide the efficiently accessible lithium storage active sites for high capacity and the enhanced pathway for ion diffusion in the charge–discharge process. Additionally, due to the strong contact between active material and conducting substrate, such an advanced nanoarchitecture enables fast electron transport across the interfaces. Thus, when used as an anode of LIBs, the resulting CONWs/NF possess an average rechargeable capacity of ≈1609 mAh g−1 at the current density of 0.5 A g−1, together with a good rate performance without any ancillary materials. The strategy demonstrated in the present study paves a new pathway for directly and facilely growing NWs on conducting substrates for energy storage applications.
Highly Oriented Electrospun P(VDF‐TrFE) Fibers via Mechanical Stretching for Wearable Motion Sensing
Authors: Ma Shaoyang , Ye Tao , Zhang Ting , Wang Zhe , Li Kaiwei , Chen Ming , Zhang Jing , Wang Zhixun , Ramakrishna Seeram , Wei Lei 
Published: May 2018

AbstractAdvances in functional fabrics enable the realization of wearable devices in the form factor of fibers that can be seamlessly adapted in our daily lives. For mechanical‐related sensing and power generation, piezoelectric materials are particularly favorable because they can convert mechanical shape changes into electric outputs. Electrospinning is a widely applied technique to produce extended length of fiber‐shaped piezoelectric devices. However, this versatile process normally results in randomly distributed fibers with poor electrical properties and limited response to mechanical stimuli. Here, a stretching‐induced alignment method is demonstrated to achieve highly oriented electrospun poly[(vinylidenefluoride‐co‐trifluoroethylene] P(VDF‐TrFE) fibers on a large scale. These globally aligned electrospun P(VDF‐TrFE) fibers exhibit an enhanced piezoelectric property and high mechanical endurance. Using this simple stretching method, a high average output voltage of 80% aligned electrospun P(VDF‐TrFE) fibers is 84.96 mV, about 266% of their original randomly distributed counterpart. Furthermore, when woven into an outfit, the aligned electrospun P(VDF‐TrFE) fiber bundle can work both individually and combined to monitor body gestures including angles of elbow bending and directions of a swinging arm, which may lead to the further development of motion‐tracking technology.
Near‐Infrared Responsive PEGylated Gold Nanorod and Doxorubicin Loaded Dissolvable Hyaluronic Acid Microneedles for Human Epidermoid Cancer Therapy
Authors: Hao Ying , Chen YuWen , Lei MinYi , Zhang TaoYe , Cao YiPing , Peng JinRong , Chen LiJuan , Qian ZhiYong 
Published: May 2018

AbstractCurrently, epidermoid cancer is one of the most common malignancies among Caucasians. Traditional treatment may yield uncomfortable side effects for the patient. In order to solve these problems, the authors develop a near‐infrared (NIR) responsive PEGylated gold nanorod (GNR‐PEG) and doxorubicin (DOX) loaded dissolvable hyaluronic acid (HA) microneedle (GNR‐PEG&DOX@HA MN) for human epidermoid cancer therapy. The as‐made GNR‐PEG&DOX@HA MNs has good skin penetration capability and heating ability. The heating can be transferred to the center of the tumor sites and the temperature is shown to rise up to 60 °C within 5 min. Meanwhile, the release behavior of the DOX from GNR‐PEG&DOX@HA MNs can be controlled by NIR light. The GNR‐PEG&DOX@HA MNs shows good cell inhibition, and the photothermal effect is shown to completely destroy A431 cells in vitro. For in vivo antitumor study, the group treated with GNR‐PEG&DOX@HA MNs transcutaneously reveals a remarkable antitumor efficacy, such that all mice are cured without recurrence under only one treatment. Hence, this novel transdermal drug delivery strategy offers hope to human epidermoid cancer therapy, and GNR‐PEG&DOX@HA MN may serve as a promising candidate in clinical translation for human epidermoid cancer therapy.
Magnetoresistance Anomaly in Topological Kondo Insulator SmB6 Nanowires with Strong Surface Magnetism
Authors: He Xingshuai , Gan Haibo , Du Zongzheng , Ye Bicong , Zhou Liang , Tian Yuan , Deng Shaozhi , Guo Guoping , Lu Haizhou , Liu Fei , He Hongtao 
Published: May 2018

AbstractTopological Kondo insulators (TKIs) are a new class of topological materials in which topological surface states dominate the transport properties at low temperatures. They are also an ideal platform for studying the interplay between strong electron correlations and topological order. Here, hysteretic magnetoresistance (MR) is observed in TKI SmB6 thin nanowires at temperatures up to 8 K, revealing the strong magnetism at the surface of SmB6. It is also found that such MR anomaly exhibits an intriguing finite size effect and only appears in nanowires with diameter smaller than 58 nm. These nontrivial phenomena are discussed in terms of the latest Kondo breakdown model, which incorporates the RKKY magnetic interaction mediated by surface states with the strong electron correlation in SmB6. It would provide new insight into the nature of TKI surface states. Additionally, a non‐monotonically temperature dependent positive magnetoresistance is observed at intermediate temperatures, suggesting the possible impurity‐band conduction in SmB6, other than the surface state transport at low temperatures and the bulk‐band transport at high temperatures.
Mitochondria‐Targeted Artificial “Nano‐RBCs” for Amplified Synergistic Cancer Phototherapy by a Single NIR Irradiation
Authors: Zhang Liang , Wang Dong , Yang Ke , Sheng Danli , Tan Bin , Wang Zhigang , Ran Haitao , Yi Hengjing , Zhong Yixin , Lin Han , Chen Yu 
Published: May 2018

AbstractPhototherapy has emerged as a novel therapeutic modality for cancer treatment, but its low therapeutic efficacy severely hinders further extensive clinical translation and application. This study reports amplifying the phototherapeutic efficacy by constructing a near‐infrared (NIR)‐responsive multifunctional nanoplatform for synergistic cancer phototherapy by a single NIR irradiation, which can concurrently achieve mitochondria‐targeting phototherapy, synergistic photothermal therapy (PTT)/photodynamic therapy (PDT), self‐sufficient oxygen‐augmented PDT, and multiple‐imaging guidance/monitoring. Perfluorooctyl bromide based nanoliposomes are constructed for oxygen delivery into tumors, performing the functions of red blood cells (RBCs) for oxygen delivery (“Nano‐RBC” nanosystem), which can alleviate the tumor hypoxia and enhance the PDT efficacy. The mitochondria‐targeting performance for enhanced and synergistic PDT/PTT is demonstrated as assisted by nanoliposomes. In particular, these “Nano‐RBCs” can also act as the contrast agents for concurrent computed tomography, photoacoustic, and fluorescence multiple imaging, providing the potential imaging capability for phototherapeutic guidance and monitoring. This provides a novel strategy to achieve high therapeutic efficacy of phototherapy by the rational design of multifunctional nanoplatforms with the unique performances of mitochondria targeting, synergistic PDT/PTT by a single NIR irradiation (808 nm), self‐sufficient oxygen‐augmented PDT, and multiple‐imaging guidance/monitoring.
Direct Semiconductor Laser Writing of Few‐Layer Graphene Polyhedra Networks for Flexible Solid‐State Supercapacitor
Authors: Liu Chunlin , Liang Hongwei , Wu Dun , Lu Xiangyu , Wang Qiang 
Published: May 2018

AbstractHere, a simple one‐step fabrication methodology is presented for continuous heteroatoms‐doped carbon polyhedra networks via direct semiconductor laser writing on polyimide sheets. It is found that these nanosized polyhedra are nonporous solids and comprised of few‐layer graphene. By the adoption of lithium containing polymer gel electrolyte, flexible solid‐state supercapacitors are designed and assembled in planar and interdigitated configuration with the irradiated plastic sheets as electrodes. When compared to their counterparts with the acid gel electrolyte, they exhibit high areal specific capacitance up to 34.7 mF cm−2 (vs ≈8 mF cm−2) at the current density of 0.1 mA cm−2. This substantial enhancement is considered to be due to the combination of Faradaic intercalation and non‐Faradaic absorption of the Li‐ions at the carbon polyhedra membrane electrodes. With the improvement of energy density, the complex of supercapacitor device is capable of lighting the liquid crystal display of a commercial hygrometer for ≈1 min.
Synthesis of Submillimeter‐Scale Single Crystal Stannous Sulfide Nanoplates for Visible and Near‐Infrared Photodetectors with Ultrahigh Responsivity
Authors: Li Qiu , Wei Aixiang , Lu Jianting , Tao Lili , Yang Yibin , Luo Dongxiang , Liu Jun , Xiao Ye , Zhao Yu , Li Jingbo 
Published: May 2018

AbstractLayered 2D semiconductors, such as graphene and transition‐metal dichalcogenides (TMDs), are receiving intensive attention owing to their great performance in electronic and optoelectronic application during the past few years. Among them, SnS has similar anisotropy to black phosphorus and high photoresponse in the near infrared range, rendering it as an ideal candidate for infrared photodetectors. In this work, large‐size (up to 330 µm) and high‐quality single‐crystalline SnS nanoplates are synthesized successfully via controlled chemical vapor deposition technique and characterized by field‐emission scanning electron microscopy, X‐ray diffraction, confocal Raman system, atomic force microscope, transmission electron microscopy, and photoluminescence spectroscopy. Photodetectors based on as‐grown SnS nanoplates are fabricated with back‐gated field effect transistors (FETs) configuration, exhibiting a high mobility of 17.1 cm2 V−1 s−1. Photodetectors based on the SnS FETs demonstrate excellent optoelectronic performance both in visible and near‐infrared spectral range. Typically, photoresponsivity of 197.7 A W−1, photoresponse time of 39 ms, and external quantum efficiency of 6.06 × 104% are exhibited under the irradiation of 405 nm laser. The wide response range and ultrahigh sensitivity make the large‐area single crystal SnS nanoplate a promising candidate for future application in optoelectronics.
Novel Route to Fe‐Based Cathode as an Efficient Bifunctional Catalysts for Rechargeable Zn–Air Battery
Authors: Han Sancan , Hu Xiaoyi , Wang Jiacheng , Fang Xiaosheng , Zhu Yufang 
Published: May 2018

AbstractEfficient bifunctional oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) catalysts are of great importance for rechargeable metal–air batteries. Herein, FeNx/C catalysts are synthesized by pyrolysis of thiourea and agarose containing α‐Fe2O3 nanoplate as Fe precursor, where α‐Fe2O3 nanoplate can prevent the aggregation of carbon sheets to effectively improve the specific surface area during the carbonization process. The FeNx/C‐700‐20 catalyst displays excellent catalytic performance for both ORR and OER activity in alkaline conditions with more positive onset potential (1.1 V vs the reversible hydrogen electrode) and half‐wave potential, higher stability, and stronger methanol tolerance in alkaline solution, which are all superior to that of the commercial Pt/C catalyst. In this study, the detailed analyses demonstrate that the coexistence of Fe‐based species and high content of Fe‐Nx both play an important role for the catalytic activity. Furthermore, FeNx/C‐700‐20 as cathode catalyst in Zn–air battery possesses higher charge–discharge stability and power density compared with that of commercial Pt/C catalyst, displaying great potential in practical implementation of for the rechargeable energy devices.
Lattices and Their Consistent Quantification
Authors: Knuth Kevin H. 
Published: May 2018

AbstractThe order‐theoretic concept of lattices is introduced along with the concept of consistent quantification where lattice elements are mapped to real numbers in such a way that preserves some aspect of the order‐theoretic structure. Symmetries, such as associativity, constrain consistent quantification, and lead to a constraint equation known as the sum rule. Distributivity in distributive lattices also constrains consistent quantification and leads to a product rule. The sum and product rules, which are familiar from, but not unique to, probability theory, arise from the fact that logical statements form a distributive (Boolean) lattice, which exhibits the requisite symmetries.
In Situ Study of the Function of Bacterioruberin in the Dual‐Chromophore Photoreceptor Archaerhodopsin‐4
Authors: Sun Chao , Ding Xiaoyan , Cui Haolin , Yang Yanan , Chen Sijin , Watts Anthony , Zhao Xin 
Published: May 2018

AbstractWhile certain archaeal ion pumps have been shown to contain two chromophores, retinal and the carotenoid bacterioruberin, the functions of bacterioruberin have not been well explored. To address this research gap, recombinant archaerhodopsin‐4 (aR4), either with retinal only or with both retinal and bacterioruberin chromophores, was successfully expressed together with endogenous lipids in H. salinarum L33 and MPK409 respectively. In situ solid‐state NMR, supported by molecular spectroscopy and functional assays, revealed for the first time that the retinal thermal equilibrium in the dark‐adapted state is modulated by bacterioruberin binding through a cluster of aromatic residues on helix E. Bacterioruberin not only stabilizes the protein trimeric structure but also affects the photocycle kinetics and the ATP formation rate. These new insights may be generalized to other receptors and proteins in which metastable thermal equilibria and functions are perturbed by ligand binding.
Nickel(II)‐Catalyzed Asymmetric Propargyl [2,3] Wittig Rearrangement of Oxindole Derivatives: A Chiral Amplification Effect
Authors: Xu Xi , Zhang Jianlin , Dong Shunxi , Lin Lili , Lin Xiaobin , Liu Xiaohua , Feng Xiaoming 
Published: May 2018

AbstractA highly enantioselective [2,3] Wittig rearrangement of oxindole derivatives was realized by using a chiral N,N′‐dioxide/NiII complex as the catalyst under mild reaction conditions. A strong chiral amplification effect was observed, and allowed access to chiral 3‐hydroxy 3‐substituted oxindoles bearing allenyl groups in high yields and enantioselectivities (up to 92 % ee) by using a ligand with only 15 % ee. A reasonable explanation was given based on the experimental investigations and X‐ray crystal structures of enantiomerically pure and racemic catalysts. Moreover, the first catalytic kinetic resolution of racemic oxindole derivatives by a [2,3] Wittig rearrangement was realized with high efficiency and stereoselectivity.
Photo‐Controlled Reversible Microtubule Assembly Mediated by Paclitaxel‐Modified Cyclodextrin
Authors: Zhang Ying‐Ming , Zhang Ni‐Yuan , Xiao Kui , Yu Qilin , Liu Yu 
Published: May 2018

AbstractThe design and construction of multi‐stimuli‐responsive supramolecular nanoassemblies that can mimic and regulate the fundamental biological processes have become a focus of interest in supramolecular chemistry. In this work, a perfect combination has been achieved between naturally occurring microtubules and artificially macrocyclic receptors. The self‐assembling morphology of microtubules can be photo‐tuned by the host–guest interaction of paclitaxel‐modified β‐cyclodextrin (PTX‐CD) and photochromic arylazopyrazole (PTX‐AAP). Moreover, the supramolecularly aggregated microtubules in a cellular environment can induce a pronounced cell morphological change and cell death. This supramolecular approach based on the secondary PTX‐AAP⊂PTX‐CD complexation provides us a facile method to reversibly control the intertubular aggregation behaviors of microtubules, which may bring new perspectives in the treatment of diseases related to improper protein aggregation.
Physicochemical Properties of Mixtures of Morama Seed Oil With Alkanols and Alkyl Acetates at 298.15 K Atmospheric Pressure
Authors: Yeboah Samuel O. , Oathotse Isaac , Ddamba Wilfred A. A. 
Published: May 2018

AbstractDensities, ρ, ultrasonic speed, u, and dynamic viscosities, η, of mixtures of morama, Tylosema esculentum, seed oil with 1‐propanol, 1‐butanol, methyl acetate, and ethyl acetate were determined over the entire composition range at 298.15 K and atmospheric pressure. Excess molar volumes, , excess molar‐free volumes , deviations in isentropic compressibility, Δκs, deviations in ultrasonic speed, Δu, deviations in dynamic viscosity, Δη, and the excess free energy of activation of viscous flow, ΔG*E, were calculated and correlated using the Redlich–Kister equation for each of the (morama seed oil + 1‐propanol or 1‐butanol or methyl acetate or ethyl acetate) mixtures. The results obtained were discussed in terms of possible dipole–dipole intermolecular interactions and structural effects.
Brief Report: Smoking in Systemic Sclerosis: A Longitudinal European Scleroderma Trials and Research Group Study
Authors: Jaeger Veronika K. , Valentini Gabriele , Hachulla Eric , Cozzi Franco , Distler Oliver , Airó Paolo , Czirják Laszlo , Allanore Yannick , Siegert Elise , Rosato Edoardo , Matucci‐Cerinic Marco , Caimmi Cristian , Henes Jörg , Carreira Patricia E. , Smith Vanessa , del Galdo Francesco , Denton Christopher P. , Ullman Susanne , De Langhe Ellen , Riccieri Valeria , Alegre‐Sancho Juan J. , Rednic Simona , Müller‐Ladner Ulf , Walker Ulrich A. ,   EUSTAR coauthors
Published: May 2018

ObjectiveData on the role of tobacco exposure in systemic sclerosis (SSc; scleroderma) severity and progression are scarce. We aimed to assess the effects of smoking on the evolution of pulmonary and skin manifestations, based on the European Scleroderma Trials and Research group database.MethodsAdult SSc patients with data on smoking history and a 12–24‐month follow‐up visit were included. Associations of severity and progression of organ involvement with smoking history and the Comprehensive Smoking Index were assessed using multivariable regression analyses.ResultsA total of 3,319 patients were included (mean age 57 years, 85% female); 66% were never smokers, 23% were ex‐smokers, and 11% were current smokers. Current smokers had a lower percentage of antitopoisomerase autoantibodies than previous or never smokers (31% versus 40% and 45%, respectively). Never smokers had a higher baseline forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC) ratio than previous and current smokers (P < 0.001). The FEV1/FVC ratio declined faster in current smokers than in never smokers (P = 0.05) or ex‐smokers (P = 0.01). The baseline modified Rodnan skin thickness score (MRSS) and the MRSS decline were comparable across smoking groups. Although heavy smoking (>25 pack‐years) increased the odds of digital ulcers by almost 50%, there was no robust adverse association of smoking with digital ulcer development.ConclusionThe known adverse effect of smoking on bronchial airways and alveoli is also observed in SSc patients; however, robust adverse effects of smoking on the progression of SSc‐specific pulmonary or cutaneous manifestations were not observed.
Inhibition of Cyclic GMP‐AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1‐Deficient Mice
Authors: An Jie , Woodward Joshua J. , Lai Weinan , Minie Mark , Sun Xizhang , Tanaka Lena , Snyder Jessica M. , Sasaki Tomikazu , Elkon Keith B. 
Published: May 2018

ObjectiveType I interferon (IFN) is strongly implicated in the pathogenesis of systemic lupus erythematosus (SLE) as well as rare monogenic interferonopathies such as Aicardi‐Goutières syndrome (AGS), a disease attributed to mutations in the DNA exonuclease TREX1. The DNA‐activated type I IFN pathway cyclic GMP‐AMP (cGAMP) synthase (cGAS) is linked to subsets of AGS and lupus. This study was undertaken to identify inhibitors of the DNA–cGAS interaction, and to test the lead candidate drug, X6, in a mouse model of AGS.MethodsTrex1−/− mice were treated orally from birth with either X6 or hydroxychloroquine (HCQ) for 8 weeks. Expression of IFN‐stimulated genes (ISGs) was quantified by quantitative polymerase chain reaction. Multiple reaction monitoring by ultra‐performance liquid chromatography coupled with tandem mass spectrometry was used to quantify the production of cGAMP and X6 drug concentrations in the serum and heart tissue of Trex1−/− mice.ResultsOn the basis of the efficacy‐to‐toxicity ratio established in vitro, drug X6 was selected as the lead candidate for treatment of Trex1−/− mice. X6 was significantly more effective than HCQ in attenuating ISG expression in mouse spleens (P < 0.01 for Isg15 and Isg20) and hearts (P < 0.05 for Isg15, Mx1, and Ifnb, and P < 0.01 for Cxcl10), and in reducing the production of cGAMP in mouse heart tissue (P < 0.05), thus demonstrating target engagement by the X6 compound. Of note, X6 was also more effective than HCQ in reducing ISG expression in vitro (P < 0.05 for IFI27 and MX1, and P < 0.01 for IFI44L and PKR) in human peripheral blood mononuclear cells from patients with SLE.ConclusionThis study demonstrates that X6 is superior to HCQ for the treatment of an experimental autoimmune myocarditis mediated in vivo by the cGAS/stimulator of IFN genes (cGAS/STING) pathway. The findings suggest that drug X6 could be developed as a novel treatment for AGS and/or lupus to inhibit activation of the cGAS/STING pathway.
3D Multi‐Agent Formation Control with Rigid Body Maneuvers
Authors: Zhang Pengpeng , de Queiroz Marcio 
Published: May 2018

AbstractIn this paper, we propose a control scheme for the formation maneuvering problem of multi‐agent systems where the team of agents can translate and rotate as a virtual rigid body in 3D. Using the single‐integrator model, we formulate the basic control law which is comprised of a formation acquisition term, function of the graph rigidity matrix, and a rigid body maneuvering term. The control is dependent on the relative position of agents that are connected in an infinitesimally and minimally rigid framework in addition to the desired rigid body motion of the formation. To facilitate the design of the rigid body maneuver, one agent in the convex hull of the formation serves as the reference point for the rotation component. A simulation study demonstrates the formation controller.