bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Imbalance in Medical Demand and Supply for Pediatric Victims in an Earthquake
Authors: Toida Chiaki , Takeuchi Ichiro , Abe Takeru , Hattori Jun , Hattori Kyoko , Takahashi Kohei , Uchiyama Munehito , Honda Hideki , Nakagawa Yosihide , Matsuda Kiyoshi , Asari Yasushi , Morimura Naoto 
Published: December 2018

ABSTRACTObjectivesWe quantified an absolute imbalance of the medical risks and the support needs for children at each disaster-based hospital in Kanagawa immediately following the occurrence of a large earthquake by using the risk resource ratio (RRR) and need for medical resources (NMR).MethodsThe RRR and NMR of 33 disaster-based hospitals were estimated through dividing the estimated number of pediatric victims by the number of critically patients. We calculated the ratio of the NMR of each hospital.ResultsThe total number of pediatric victims in Kanagawa was estimated at 8,391. The total number of vacant beds for pediatric victims was 352. The median RRR and NMR of the total number of pediatric victims were 27 and 224. The median RRR and NMR of the number of critically ill pediatric patients were 27 and 12.ConclusionsThe absolute imbalance of the RRR and NMR for children in Kanagawa was quantified. This suggests that we might embark on preparedness strategies for children in advance. (Disaster Med Public Health Preparedness. 2018;13:672–676)
CONSTRUCTING TYPES IN DIFFERENTIALLY CLOSED FIELDS THAT ARE ANALYSABLE IN THE CONSTANTS
Authors: JIN RUIZHANG 
Published: December 2018

AbstractAnalysability of finiteU-rank types are explored both in general and in the theory${\rm{DC}}{{\rm{F}}_0}$. The well-known fact that the equation$\delta \left( {{\rm{log}}\,\delta x} \right) = 0$is analysable in but not almost internal to the constants is generalized to show that$\underbrace {{\rm{log}}\,\delta \cdots {\rm{log}}\,\delta }_nx = 0$is not analysable in the constants in$\left( {n - 1} \right)$-steps. The notion of acanonical analysisis introduced–-namely an analysis that is of minimal length and interalgebraic with every other analysis of that length. Not every analysable type admits a canonical analysis. Using properties of reductions and coreductions in theories with the canonical base property, it is constructed, for any sequence of positive integers$\left( {{n_1}, \ldots ,{n_\ell }} \right)$, a type in${\rm{DC}}{{\rm{F}}_0}$that admits a canonical analysis with the property that theith step hasU-rank${n_i}$.
ENAYAT MODELS OF PEANO ARITHMETIC
Authors: ABDUL-QUADER ATHAR 
Published: December 2018

AbstractSimpson [6] showed that every countable model ${\cal M} \models PA$ has an expansion $\left( {{\cal M},X} \right) \models P{A^{\rm{*}}}$ that is pointwise definable. A natural question is whether, in general, one can obtain expansions of a nonprime model in which the definable elements coincide with those of the underlying model. Enayat [1] showed that this is impossible by proving that there is ${\cal M} \models PA$ such that for each undefinable class X of ${\cal M}$, the expansion $\left( {{\cal M},X} \right)$ is pointwise definable. We call models with this property Enayat models. In this article, we study Enayat models and show that a model of $PA$ is Enayat if it is countable, has no proper cofinal submodels and is a conservative extension of all of its elementary cuts. We then show that, for any countable linear order γ, if there is a model ${\cal M}$ such that $Lt\left( {\cal M} \right) \cong \gamma$, then there is an Enayat model ${\cal M}$ such that $Lt\left( {\cal M} \right) \cong \gamma$.
ACCEPTABLE COLORINGS OF INDEXED HYPERSPACES
Authors: SCHMERL JAMES H. 
Published: December 2018

AbstractPrevious results about n-grids with acceptable colorings are extended here to n-indexed hyperspaces, which are structures ${\cal A} = \left( {A;{E_0},{E_1}, \ldots ,{E_{n - 1}}} \right)$, where each ${E_i}$ is an equivalence relation on A.
THE UNITY AND IDENTITY OF DECIDABLE OBJECTS AND DOUBLE-NEGATION SHEAVES
Authors: MENNI MATÍAS 
Published: December 2018

AbstractLet ${\cal E}$ be a topos, ${\rm{Dec}}\left( {\cal E} \right) \to {\cal E}$ be the full subcategory of decidable objects, and ${{\cal E}_{\neg \,\,\neg }} \to {\cal E}$ be the full subcategory of double-negation sheaves. We give sufficient conditions for the existence of a Unity and Identity ${\cal E} \to {\cal S}$ for the two subcategories of ${\cal E}$ above, making them Adjointly Opposite. Typical examples of such ${\cal E}$ include many ‘gros’ toposes in Algebraic Geometry, simplicial sets and other toposes of ‘combinatorial’ spaces in Algebraic Topology, and certain models of Synthetic Differential Geometry.
THE VARIETY OF COSET RELATION ALGEBRAS
Authors: GIVANT STEVEN , ANDRÉKA HAJNAL 
Published: December 2018

AbstractGivant [6] generalized the notion of an atomic pair-dense relation algebra from Maddux [13] by defining the notion of a measurable relation algebra, that is to say, a relation algebra in which the identity element is a sum of atoms that can be measured in the sense that the “size” of each such atom can be defined in an intuitive and reasonable way (within the framework of the first-order theory of relation algebras). In Andréka--Givant [2], a large class of examples of such algebras is constructed from systems of groups, coordinated systems of isomorphisms between quotients of the groups, and systems of cosets that are used to “shift” the operation of relative multiplication. In Givant--Andréka [8], it is shown that the class of these full coset relation algebras is adequate to the task of describing all measurable relation algebras in the sense that every atomic and complete measurable relation algebra is isomorphic to a full coset relation algebra.Call an algebra $\mathfrak{A}$ a coset relation algebra if $\mathfrak{A}$ is embeddable into some full coset relation algebra. In the present article, it is shown that the class of coset relation algebras is equationally axiomatizable (that is to say, it is a variety), but that no finite set of sentences suffices to axiomatize the class (that is to say, the class is not finitely axiomatizable).
CONCERNING SUMMABLE SZLENK INDEX
Authors: CAUSEY RYAN MICHAEL 
Published: December 2018

AbstractWe generalize the notion of summable Szlenk index from a Banach space to an arbitrary weak*-compact set. We prove that a weak*-compact set has summable Szlenk index if and only if its weak*-closed, absolutely convex hull does. As a consequence, we offer a new, short proof of a result from Draga and Kochanek [J. Funct. Anal. 271 (2016), 642–671] regarding the behavior of summability of the Szlenk index under c0 direct sums. We also use this result to prove that the injective tensor product of two Banach spaces has summable Szlenk index if both spaces do, which answers a question from Draga and Kochanek [Proc. Amer. Math. Soc. 145 (2017), 1685–1698]. As a final consequence of this result, we prove that a separable Banach space has summable Szlenk index if and only if it embeds into a Banach space with an asymptotic c0 finite dimensional decomposition, which generalizes a result from Odell et al. [Q. J. Math. 59, (2008), 85–122]. We also introduce an ideal norm $\mathfrak{s}$ on the class $\mathfrak{S}$ of operators with summable Szlenk index and prove that $(\mathfrak{S}, \mathfrak{s})$ is a Banach ideal. For 1 ⩽ p ⩽ ∞, we prove precise results regarding the summability of the Szlenk index of an ℓp direct sum of a collection of operators.
Longitudinal changes in brain activation during anticipation of monetary loss in bipolar disorder
Authors: Manelis Anna , Stiffler Richelle , Lockovich Jeanette C. , Almeida Jorge R. C. , Aslam Haris A. , Phillips Mary L. 
Published: December 2018

AbstractBackgroundIndividuals with bipolar disorder (BD) show aberrant brain activation patterns during reward and loss anticipation. We examined for the first time longitudinal changes in brain activation during win and loss anticipation to identify trait markers of aberrant anticipatory processing in BD.MethodsThirty-four euthymic and depressed individuals with BD-I and 17 healthy controls (HC) were scanned using functional magnetic resonance imaging twice 6 months apart during a reward task.ResultsHC, but not individuals with BD, showed longitudinal reductions in the right lateral occipital cortex (RLOC) activation during processing of cues predicting possible money loss (p-corrected <0.05). This result was not affected by psychotropic medication, mood state or the changes in depression/mania severity between the two scans in BD. Elevated symptoms of subthreshold hypo/mania at baseline predicted more aberrant longitudinal patterns of RLOC activation explaining 12.5% of variance in individuals with BD.ConclusionsIncreased activation in occipital cortex during negative outcome anticipation may be related to elevated negative emotional arousal during anticipatory cue processing. One interpretation is that, unlike HC, individuals with BD were not able to learn at baseline that monetary losses were smaller than monetary gains and were not able to reduce emotional arousal for negative cues 6 months later. Future research in BD should examine how modulating occipital cortical activation affects learning from experience in individuals with BD.
Seed fate and seedling recruitment in monkey latrines in rustic cocoa plantations and rain forest in southern Mexico
Authors: Zárate Diego A. , Andresen Ellen , Santos-Heredia Carolina 
Published: December 2018

AbstractPrimates are important seed dispersers in natural ecosystems and agro-ecosystems, but the latter scenario remains under-studied. The degree to which primates favour plant regeneration greatly depends on post-dispersal processes. The main objective of this study was to compare patterns of seed/seedling fate and seedling recruitment in two habitats of the black howler monkey (Alouatta pigraLawrence 1933), rustic cocoa and rain forest, and two types of seed-deposition locations, monkey latrines and control locations. Field experiments were carried out within the non-overlapping home ranges of six monkey groups, three in cocoa and three in forest. Seed and seedling fates were assessed for one focal tree species,Brosimum lactescens. The probabilities of seed survival (0.52), germination (0.72), seedling establishment (0.73) and early seedling survival (0.38) were not affected by habitat or seed-deposition location. Late seedling survival was similar in the two habitats but was higher in control locations (0.22) than in latrines (0.09). In cocoa, 4641 seedlings of 59 species were recorded, in forest 3280 seedlings of 68 species. Seedling recruitment was similar in both habitats, but latrines had higher densities than control locations. The importance of agro-ecosystems with low management intensity for the maintenance of ecological processes in anthropogenic landscapes is discussed.
Xenia in bahiagrass: gene expression at initial seed formation
Authors: Pozzi Florencia I. , Pratta Guillermo R. , Acuña Carlos A. , Felitti Silvina A. 
Published: December 2018

AbstractXenia is the direct effect of pollen genotype on the development and characteristics of the seed and fruit in the period that spans from fertilization to seed germination. Xenia effects cause phenotypic variations in the seed and fruit, which have importance for seed and fruit production but are not heritable to the progeny. Two hypotheses have been proposed as a mechanism for xenia: the hormonal hypothesis and the mobile mRNAs hypothesis. Although xenia effects have been studied in seeds and fruits in many crops, its effects and mechanism have been poorly studied at the molecular level. The aim of this work was to perform an initial screening of the xenia effect in the hybrid endosperm at the molecular level by differential gene expression among different pollen genotype sources from Paspalum notatum Flüggé. In order to characterize xenia effects and mechanisms, crosses were made between an emasculated mother plant with donors from two different pollen genotypes. RNA was isolated from ovaries 3 h after pollination. Some of the 24 differentially expressed transcript-derived fragments (DETDFs) provided relevant information. Four of those DETDFs were related to germination, pollen tube growth and pollen–pistil interaction. Seven DETDFs were associated with seed development and production. Finally, four DETDFs were predicted to encode for mobile mRNAs. These DETDFs might be involved in xenia effects and mechanisms in P. notatum.
Fulminant cytomegalovirus myocarditis in an infant with concomitant large atrial and ventricular septal defects: medical intervention strategy for functional cardiac regeneration
Authors: Schrewe Roland , Esmaeili Anoosh , Behnke-Hall Kachina , Schranz Dietmar 
Published: December 2018

AbstractA cytomegalovirus-associated heart failure in a young infant with atrial and ventricular septal defects is reported in this case report. The patient recovered by an anti-congestive and anti-viral therapy with an extra percutaneous transcatheter treatment strategy. In the context of bi-ventricular predominant right heart failure associated with supra-systemic pulmonary hypertension, the already closed arterial duct was re-opened and stented to unload the right ventricle and thereby augment the systemic blood flow. Either the left-to-right shunting atrial septal defect or bi-directional shunting ventricular septal defect was involved in the disease process and was not able to avoid global heart failure. After clinical improvement, the stented duct was shunted left-to-right and was occluded with an ADO-II-AS. During the same procedure the atrial septal defect was closed with an Amplatzer-ASD occluder, while the peri-membranous ventricular septal defect was closed with an ADO-II occluder 2 months later.
A New Seismic Stratigraphy in the Indian‐Atlantic Ocean Gateway Resembles Major Paleo‐Oceanographic Changes of the Last 7 Ma
Authors: Gruetzner Jens , Jiménez Espejo Francisco J. , Lathika Nambiyathodi , Uenzelmann‐Neben Gabriele , Hall Ian R. , Hemming Sidney R. , LeVay Leah J. ,   the Expedition 361 Scientists
Published: December 2018

AbstractThe exchange of water masses between the Indian Ocean and the Atlantic constitutes an integral interocean link in the global thermohaline circulation. Long‐term changes in deep water flow have been studied using seismic reflection profiles but the seismic stratigraphy was poorly constrained and not resolved for the time period from the late Miocene onward. Here we present results from International Ocean Discovery Program Site U1475 (Agulhas Plateau) located over a sediment drift proximal to the entrance of North Atlantic Deep Water into the Southern Ocean and South Indian Ocean. Site U1475 comprises a complete carbonate‐rich stratigraphic section of the last ~7 Ma that provides an archive of climate‐induced variations in ocean circulation. Six marker reflectors occurring in the upper 300 m of the drift are identified here for the first time. The formation of these reflectors is mainly due to density changes that are mostly caused by changes in biogenic versus terrigenous sediment deposition. Synthetic seismograms allow age assignments for the horizons based on biostratigraphy and magnetostratigraphy. Prominent reflectors are related to late Pleistocene glacial/interglacial variability, the middle and early Pleistocene transitions, and the onset of the northern hemisphere glaciation. A peculiar early Pliocene interval (~5.3–4.0 Ma) bounded by two reflectors is characterized by fourfold elevated sedimentation rates (>10 cm/kyr) and the occurrence of sediment waves. We argue that this enhanced sediment transport to the Agulhas Plateau was caused by a reorganization of the bottom current circulation pattern due to maximized inflow of North Atlantic Deep Water.
The Mid‐Atlantic Ridge Near 13°20′N: High‐Resolution Magnetic and Bathymetry Imaging
Authors: Searle R. C. , MacLeod C. J. , Peirce C. , Reston T. J. 
Published: December 2018

AbstractWe describe detailed magnetic and bathymetric studies around 13°N on the Mid‐Atlantic Ridge, a site of extensive detachment faulting. Inversion of closely spaced sea surface magnetic anomalies reveals a disorganized pattern of magnetization, with anomalies younger than anomaly 2 being poorly delineated. The Brunhes anomaly width is highly variable but averages ~60% of that predicted for the regional spreading rate. It is often split, both along and across axis, by apparently reversely magnetized crust. Gaps in the Brunhes anomaly match gaps in the neovolcanic zone inferred from acoustic backscatter. A strong negative magnetization is associated with the oceanic core complex (OCC) at 13°20′N (OCC1320) and is inferred to arise from exhumed old, reversely magnetized lithosphere. The inferred position of the magmatic axis implies ~30% asymmetry of crustal accretion post‐anomaly‐2. Higher spatial resolution magnetic anomalies near the seafloor, measured by autonomous underwater vehicle, are qualitatively similar to earlier deep‐towed data but differ somewhat from the sea surface magnetics. We interpret this mismatch as reflecting the differing sensitivities of the two observing geometries and the existence of a highly heterogeneous topography and magnetization. This suggests that a strongly three‐dimensional structure exists, more compatible with a geodynamic model where neighboring OCCs are not connected but evolve independently. A modeled near‐seafloor profile through OCC1320 shows low positive magnetization below the smooth dome. A second profile, running E‐W between two OCCs, shows high magnetization coinciding with a large seamount, reflecting recent off‐axis volcanism. Measured microbathymetry reveals extensive small volcanic cones on this seamount and confirms previous interpretations of OCC morphology.
Reactive Iron and Iron‐Bound Organic Carbon in Surface Sediments of the River‐Dominated Bohai Sea (China) Versus the Southern Yellow Sea
Authors: Wang Di , Zhu Mao‐Xu , Yang Gui‐Peng , Ma Wei‐Wei 
Published: December 2018

AbstractFactors influencing reactive Fe cycling and its protection of organic carbon (OC) in sediments are poorly understood. Here we comparatively study Fe speciation and Fe‐associated OC (Fe‐OC) in surface sediments of the Bohai Sea (BHS) and southern Yellow Sea (SYS), two seas with common sediment sources but different depositional regimes. Though significant sequestration of highly reactive Fe (FeHR) is expected in the estuarine system stream from the river‐dominated BHS, this pool is, however, slightly enriched in the BHS sediments relative to their source material. This reconfirms a previous speculation of sedimentary FeHR enrichment in semi‐protected settings. Relative to the BHS, the SYS sediments are depleted of FeHR, despite common sediment sources of these two areas. Estuarine pre‐enrichment and subsequent redistribution of FeHR in the BHS, and aging of Fe‐bearing authigenic clays during transport from the BHS to the SYS are potential mechanisms for the depletion. The fractions (fFe‐OC) of Fe‐OC in total OC in sediments of the two seas are at the lower end for soils and sediments, indicating Fe being a minor “rusty sink.” 13CFe‐OC fractionations indicate preferential sequestration of terrestrial OC by Fe oxides in the BHS, in contrast with preferential retention of marine OC in the SYS. Different fractionations of 13CFe‐OC in the two seas are a net result of selective adsorption of OC by Fe oxides and selective stabilization of OC during Fe reductive dissolution. Preferential sequestration of terrestrial OC may exert an important influence on distribution and compositions of OC buried in the river‐dominated system.
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology
Authors: Went Molly , Sud Amit , Speedy Helen , Sunter Nicola J. , Försti Asta , Law Philip J. , Johnson David C. , Mirabella Fabio , Holroyd Amy , Li Ni , Orlando Giulia , Weinhold Niels , van Duin Mark , Chen Bowang , Mitchell Jonathan S. , Mansouri Larry , Juliusson Gunnar , Smedby Karin E , Jayne Sandrine , Majid Aneela , Dearden Claire , Allsup David J. , Bailey James R. , Pratt Guy , Pepper Chris , Fegan Chris , Rosenquist Richard , Kuiper Rowan , Stephens Owen W. , Bertsch Uta , Broderick Peter , Einsele Hermann , Gregory Walter M. , Hillengass Jens , Hoffmann Per , Jackson Graham H. , Jöckel Karl-Heinz , Nickel Jolanta , Nöthen Markus M. , da Silva Filho Miguel Inacio , Thomsen Hauke , Walker Brian A. , Broyl Annemiek , Davies Faith E. , Hansson Markus , Goldschmidt Hartmut , Dyer Martin J. S. , Kaiser Martin , Sonneveld Pieter , Morgan Gareth J. , Hemminki Kari , Nilsson Björn , Catovsky Daniel , Allan James M. , Houlston Richard S. 
Published: December 2018

AbstractThe clustering of different types of B-cell malignancies in families raises the possibility of shared aetiology. To examine this, we performed cross-trait linkage disequilibrium (LD)-score regression of multiple myeloma (MM) and chronic lymphocytic leukaemia (CLL) genome-wide association study (GWAS) data sets, totalling 11,734 cases and 29,468 controls. A significant genetic correlation between these two B-cell malignancies was shown (Rg = 0.4, P = 0.0046). Furthermore, four of the 45 known CLL risk loci were shown to associate with MM risk and five of the 23 known MM risk loci associate with CLL risk. By integrating eQTL, Hi-C and ChIP-seq data, we show that these pleiotropic risk loci are enriched for B-cell regulatory elements and implicate B-cell developmental genes. These data identify shared biological pathways influencing the development of CLL and, MM and further our understanding of the aetiological basis of these B-cell malignancies.
Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies
Authors: Shriver-Lake Lisa C. , Liu Jinny L. , Zabetakis Dan , Sugiharto Victor A. , Lee Cheng-Rei , Defang Gabriel N. , Wu Shuenn-Jue L. , Anderson George P. , Goldman Ellen R. 
Published: December 2018

AbstractReliable detection and diagnosis of dengue virus (DENV) is important for both patient care and epidemiological control. Starting with a llama immunized with a mixture of recombinant nonstructural protein 1 (NS1) antigen from the four DENV serotypes, a phage display immune library of single domain antibodies was constructed and binders selected which exhibited specificity and affinity for DENV NS1. Each of these single domain antibodies was evaluated for its binding affinity to NS1 from the four serotypes, and incorporated into a sandwich format for NS1 detection. An optimal pair was chosen that provided the best combination of sensitivity for all four DENV NS1 antigens spiked into 50% human serum while showing no cross reactivity to NS1 from Zika virus, yellow fever virus, tick-borne encephalitis virus, and minimal binding to NS1 from Japanese encephalitis virus and West Nile virus. These rugged and robust recombinant binding molecules offer attractive alternatives to conventional antibodies for implementation into immunoassays destined for resource limited locals.