bluuebunny/crossref_metadata_2025_split huggingface dataset:
Airway management in patients with oral cavity or oropharyngeal cancer: A single-institution retrospective study
Authors: Zheng Gang , Feng Lei , Lewis Carol M 
Published: January 2019

Abstract
Background: Oral cavity and oropharyngeal cancer impose significant threat to airway management. Head and neck radiotherapy (HNRT) may further increase the difficulty of tracheal intubation.
Methods: The tracheal intubation status between the two patient groups (treated vs. untreated with HNRT) was compared. The t test was used to evaluate differences in continuous variables between the 2 groups. Fisher’s exact test or a chi-square test was used to test for associations between radiation status and patient characteristics that may be associated with difficult tracheal intubation. Odds ratio and its confidence interval were used to assess the effect of radiation status on intubation status.
Results: The data of 4011 patients were reviewed. The final cohort of 472 matched patients in age, sex and body mass index consisted of 236 patients who had HNRT before surgery and 236 who had upfront surgery without HNRT. The percentage of patients who had restricted neck range of motion in the HNRT group was significantly higher than in the control group (22.3% vs. 11.0%; P = 0.001). The proportion of patients with trismus (P = 0.11) and with difficult tracheal intubation (p = 0.73) did not differ significantly between the 2 groups. 12.7% patients in the study had difficult tracheal intubation. Patients who had mallampati scores of 3 or 4 had significantly higher rate of difficult tracheal intubation than did patients with mallampati scores of 1 or 2 (17.8% vs. 8.7%; p = 0.004). Multivariate logistic regression model showed no difference between HNRT and intubation status after adjusting neck range of motion and mallampati score (OR=0.91, 95% CI: 0.510 to1.612).
Conclusions: Patients treated with HNRT was not associated with additional risk of difficult tracheal intubation. Mallampati score may be a sensitive measurement for difficult tracheal intubation in patients with oral cavity or oropharyngeal cancer.
Keywords: Radiotherapy, cancer, trismus, upper aerodigestive track, airway.
Paraneoplastic neuromyelitis optica spectrum disorder associated with breast cancer: a case report and literature review
Authors: Yuan Junliang , Jia Zejin , Qin Wei , Hu Wenli 
Published: January 2019

Abstract
Background: Neuromyelitis optica spectrum disorder (NMOSD) is an astrocytopathy with demyelinating lesions caused by aquaporin 4 (AQP4) antibodies. Although most commonly an idiopathic autoimmune condition, NMOSD may also occur as a paraneoplastic syndrome in rare instances.
Case presentation: Herein, we report a rare case of a 60-year-old woman with paraneoplastic NMOSD associated with breast cancer.
Conclusions: Our findings increase the recognition that NMOSD may present as a paraneoplastic neurological syndrome associated with breast cancer. Our case also raises awareness of an important complication of neurological complications of breast cancer. Early diagnosis of paraneoplastic NMOSD may be imperative for a better prognosis.
Keywords: Neuromyelitis optica spectrum disorder, paraneoplastic syndrome, breast cancer.
IL-10 Promotes Glioma Cell Growth and Invasion via Upregulation of KPNA2 In vitro
Authors: Zhang Zihao , Huang Xiaoming , Li Jie , Fan Haitao , Yang Fan , Zhang Rui , Yang Yihang , Feng Shaobin , He Dong , Sun Wei , Xin Tao 
Published: January 2019

Abstract
Background: Glioma is one of the leading causes of death worldwide with high incidence, recurrence and mortality. IL-10 is a cytokine with dual function in many types of tumors. Although IL-10 is overexpressed and promotes tumor progression in human primary brain tumor, the mechanisms are largely unknown.
Methods: Glioma cells were treated with different dosages of IL-10. The cell growth was detected by CCK8, and the invasion was measured by Transwell. The relative expression of mRNAs was detected by Quantitative real-time PCR (q-PCR).
Results: We found that IL-10 treatment significantly enhanced glioma cell growth and invasion. And KPNA2 was significantly upregulated after treatment with IL-10. By performing knockdown experiments, we found that the glioma cell growth and invasion were significantly declined.
Conclusions: The results indicated that knockdown of KPNA2 significantly inhibited the growth and invasion of glioma cells. And IL-10 promotes glioma progression via upregulation of KPNA2. This study will be of important significance and provides a potential target for treatment of patients with glioma.
Keywords: Cell growth, cell invasion, glioma, IL-10, KPNA2.
Vision status of children aged 7 - 15 years referred from school vision screening in Norway during 2003 - 2013: a retrospective study
Authors: Falkenberg Helle K , Langaas Trine , Svarverud Ellen 
Published: January 2019

Abstract
Background: Undetected vision problems are an important cause of reduced academic achievement, performance in everyday life and self-esteem. This receives little attention in national health care services even though most of these vision problems are easily correctable. Data on how many schoolchildren are affected are limited. This study aims to increase the knowledge of vision status in primary and secondary school children by retrospectively describing the vision status of children referred from vision screening during the ten year period 2003 – 2013.
Methods: Of 1126 (15 %) children referred to the university eye clinic, all 782 who attended were included. Patient records were reviewed with regards to symptoms, refractive error, best corrected logMAR visual acuity (BCVA), binocular vision, ocular health and management outcomes.
Results: Previously undetected vision problems were confirmed in 650 (83 %) of the children. The most frequent outcomes were glasses (346) or follow up (209), but types of treatment modalities varied with age. Mean refractive errors were hyperopic for all age groups, but reduced with age (ANOVA, p < .001). Refractive errors did not change across the decade (linear regression, all p > .05). Mean BCVAs were better than 0.0 and improved with age (ANOVA, p < .001). The most prevalent symptoms were headaches (171), near vision problems (149), and reduced distance vision (107).
Conclusions: The vision screening identified children with previously undetected visual problems. There was no change in refractive errors for either age group over the decade. Importantly, most of the problems were solved with glasses. Types of visual problems varied with age, which stresses the importance of regular eye examinations, and raised awareness among parents and teaching staff.
Keywords: Health care services, children, vision examination, visual status, refractive errors.
A comparison between a white LED confocal imaging system and a conventional flash fundus camera using chromaticity analysis
Authors: Sarao Valentina , Veritti Daniele , Borrelli Enrico , Sadda SriniVas R , Poletti Enea , Lanzetta Paolo 
Published: January 2019

Abstract
BACKGROUND: Conventional flash fundus camera captures color images that are over-saturated in the red channel, producing a retinal picture that looks washed-out and uniform. A white LED confocal device was recently introduced to provide a neutral-looking retinal image. With this study we aimed to evaluate the color rendering properties of the white LED confocal system and to compare it to a conventional flash fundus camera through the use of chromaticity analysis.
METHODS: A fully automated white LED confocal device (Eidon, Centervue, Padova, Italy) was used to capture fundus images from healthy volunteers and patients with retinal diseases. The same pictures were acquired with a flash fundus camera (Triton, Topcon Corporation, Tokyo, Japan). All color images were evaluated with respect to the chromaticity. Color analysis was performed according to the image color signature. Color signature of an image was defined as the distribution of its pixels in the rgb chromaticity space. The descriptors used for the analysis are the average and variability of the barycenter positions, the average of the variability and the number of unique colors (NUC) of all signatures.
RESULTS: Two hundred thirty-three color fundus photographs were acquired with each retinal camera. The images acquired by confocal white LED device demonstrated an average barycenter position (rgb = [0.448, 0.328, 0.224]) closer to the center of the chromaticity space, while conventional fundus camera provides images with a clear shift toward red at the expense of the blue and green (rgb = [0.574, 0.278, 0.148] (p<0.001). The variability of the barycenter positions was higher in white LED confocal system than in conventional flash fundus camera. The average variability of the distributions was higher (0.003 ± 0.007, p<0.001) in the Eidon images compared to Topcon camera, indicating a greater richness of color. The NUC percentage was higher for white LED confocal device than for conventional flash fundus camera (0.071% versus 0.025%, p<0.001).
CONCLUSIONS: Confocal white LED system provides well-balanced color images with a wider richness of color content compared to conventional flash fundus camera. The overall higher chromaticity of Eidon device may provide benefits in terms of discriminative power and diagnostic accuracy.
KEYWORDS: Chromaticity; Confocal white LED system; conventional flash fundus camera; Eidon; Topcon.
Influencing the Relationship between Job Clarity and Turnover Intention through User Training During Enterprise System Implementation
Authors: Brattin Rick L. , Davis Joshua M. , Brahnam Sheryl 
Published: January 2019

Enterprise system (ES) implementations introduce pervasive and disruptive change to organizations. End-users struggling to cope with such change often develop an internal self-preservation narrative that, if not managed, can lead to employee turnover. Turnover is a visibly-assertive response to ES implementations that has lasting negative effects on organizations. The job role literature suggests that an individualâ€™s intention to leave an organization is greater when they lack clarity concerning their own work tasks and their role in achieving broader organizational goals. These clarity perceptions evolve during ES implementations as individuals become aware that their existing job context is no longer relevant to the post-implementation organization. It seems likely that the strength of relationship between job clarity and turnover intention will also evolve during this time. Accordingly, this study uses PLS-SEM multi-group analysis to examine changes in this relationship during an ES implementation at a Fortune 100 manufacturer and finds a significant increase in the influence of job clarity deficiencies on turnover intention following end-user training. These results suggest that ES implementation teams should focus their efforts on building job clarity of the post-implementation work context.
PENGARUH PENAMBAHAN ABU SEKAM PADI SEBAGAI CAMPURAN TERHADAP KEKUATAN BATU BATA
Authors: Zebua Deslina , Sinulingga Karya 
Published: January 2019

Penelitian ini bertujuan untuk mengetahui pengaruh dan komposisi terbaik batubata menggunakan abu sekam padi dengan tanah liat terhadap kuat tekan, daya serap air, massa jenis batu bata serta mengetahui struktrur kristal dan fase-fase pengisi pada batu bata. Metode penelitian ini dilakukan dengan menambahkan abu sekam padi (0%, 2%, 4%, 6%, 8% ) dengan tanah liat campuran yang homogen. Penelitian ini dilakukan pencetakan, pengeringan alami selama 14 hari, pembakaran secara tradisional selama 3 x 24 jam, dan pendinginan batu bata selama 3 x 24 jam. Berdasarkan standarisasi SII-0021-1978 batu bata merah kuat tekan batu bata penambahan abu sekam padi 2%, 4%, dan 6% mendekati standar mutu kelas 50 sebesar 5.0 MPa dibandingkan tanpa menggunakan abu sekam padi. Penambahan abu sekam padi sebanyak 8% ternyata menunjukkan daya serap air lebih tinggi dengan nilai section rate yang diijinkan 20 gr/dm2/menit di bandingkan batu bata dengan abu sekam padi 0%, 2%, 4%, dan 6% dengan lama perendaman selama 6 menit. Dari data pengujian massa jenis batu bata dengan menambahkan abu sekam padi pada tanah liat menunjukkan bahwa semakin banyaknya campuran abu sekam padi maka semakin menurunnya massa jenis batu bata. Hasil analisis X-Ray Difraction penambahan 2% abu sekam padi atau tanpa menggunakan abu sekam padi pada tanah liat memiliki fase dominan SiO2 (Quartz) dengan stuktur Kristal trigonal (hexagonal axes).Kata Kunci : Batu bata, Abu Sekam Padi, Massa Jenis, Daya Serap Air, Kuat Tekan, X-Ray Difraction.
KARAKTERISTIK BETON RINGAN PASCA BAKAR MENGGUNAKANSTYROFOAM DENGAN PELARUT TOLUENA
Authors: Gaol Ervinna Lumban , Harahap Mukti Hamzah 
Published: January 2019

Telah dilakukan penelitian karakteristik beton dari Styrofoam dengan pelarut toluena paska bakar. Penelitian ini bertujuan untuk mengetahui pengaruh suhu pembakaran terhadap beton dengan menggunakan Styrofoam, dan pelarut toluena terhadap kuat tekan, dan pola keretakan beton. Metode pembuatan yang dilakukan adalah beton dibuat berbentuk kubus 15 x 15 x 15 cm. Campuran beton yang digunakan mengacu pada beton mutu rendah K175 dengan semen : pasir : kerikil adalah 1 : 2 : 3 dengan FAS 0,5. Beton normal sebagai pembanding dengan beton normal yang mengalami proses pembakaran. Pada penelitian ini dibuat variasi komposisi styrofoam sebesar 14%, 16%, dan 18% dari berat agregat kasar yang digunakan. Setelah melalui masa peredaman 28 hari, kemudian dilakukan pembakaran pada mesin furnance pada suhu 3000 C, 4000 C, dan 5000 C dengan waktu penahanan selama 2 jam. Setelah itu, proses pembakaran dihentikan lalu direndam ke dalam air selama ± 4 menit, kemudian didiamkan selama 24 jam dengan temperatur ruangan kemudian beton diuji dengan metode uji kuat tekan dengan prosedur yang ada. Berdasarkan hasil penelitian diperoleh hasil nilai kuat tekan beton pasca bakar pada tiga variasi suhu dengan komposisi 14% - 18% di dapatkan hasil paling optimal pada campuran 14% sekitar 15,64 MPa. Sedangkan komposisi campuran diatas 14% mengalami penurunan. Pola keretakan beton dengan komposisi penambahan Styrofoam 14%- 18% tampak terlihat ada retakan. Dari hasil penelitian ini terlihat bahwa suhu berpengaruh dalam menentukan sifat mekanik beton dan nilai keoptimalan ditunjukkan pada benda uji suhu 300⁰C pada penggunaan komposisi Styrofoam 14% yang memenuhi syarat kekuatan tekan beton normal sekitar 15,64 MPa.Kata Kunci : Beton Ringan, Pasca Bakar, Styrofoam, Uji Kuat Tekan, Pola Keretakan.
Deviation of Meanings with Homonymy as an Effort to Build Humor in Meme: A Semantic Study
Authors: Sukardi Mochamad Ighfir , Sumarlam Sumarlam , Marmanto Sri 
Published: January 2019

The purpose of this study is (1) Describe how the use of homonymy for deviation of meaning as an effort to build humor in meme. (2) Describes a pattern of deviations of meaning that utilize homonymy in memes. This research is a descriptive-qualitative research. The data were collected using the method of simak and technique of notes. Data analysis in this research use method of match referential and connecting techniques to support codification, reduction, display, and interpretation in accordance with qualitative research framework. The results of this research, found the use of relations of homonymous meaning include the word base, derivative, foreign, and slang. Also found a deviation of meaning by utilizing homonymy that occurs due to euphemism, naming, and awarding pause. In addition to homonymy also found the use of homophony and then homography of word abbreviation. There are three patterns used to make deviations of meaning by utilizing homonymy. (1) The abused word is accompanied by text as explanatory. (2) The abused word is accompanied by the picture as explanatory. (3) The abused word does not appear in the language symbol but the image with the text as explanatory. The holder of the important role of deviation of meaning in the meme is the image and the use of collocation. The right collocation is capable of tricking the reader before finally being startled by a second meaning. Collocation can determine the successful use of homonymy to build humor in a meme. If the meaning of collocation fails to deliver the reader to the meaning presented, then the meaning of the surprise fails to show.
A BOOK REVIEW: FEMINISM ANDNERSUS FEMINITY OF MODERN WOMEN
Authors: Wohangara B. Retang 
Published: January 2019

One important theme attached to pop culture is the politics of representation and sub-cultural identity. The pop singer Madonna and then the Spice Girls are frequently regarded as the representation of modern women offering a different face of feminism ideology. Successfully entering the market
competition, Madonna, through her cry of 'material girl', characterizes herself as an independent woman in the still dominating patriarchal world while challenging the burden of
morality placed on the shoulders of women. She asks young women to rebel against male-centred traditions and unashamedly exposes her sensuality as a source of power and even domination, or in short celebrating 'being women'. The flag of Girl Power is also waved by the 1990'sBritish female
singers, the Spice Girls, who call young girls to "be strong, be brave, be loud and control your own destiny. Believe that your self can do anything you want to do and be confident. We have to be independent, but it does not mean that you don't need a boy" (Swastika 2004: 66).
Uric Acid Biosensor Based on Biofilm of L. plantarum using Screen-Printed Carbon Electrode Modified by Magnetite
Authors: Fatonah Dian Siska Rahma , Saprudin Deden , Iswantini Dyah , Nurhidayat Novik 
Published: January 2019

Biosensor based on biofilm of L. plantarum has been successfully done for determination of uric acid in human urine compared with colorimetric enzymatic produced relative error of less than 5%. L. plantarum has uricase activity to react with uric acid, to maintain the stability of bacteria forming themselves into biofilms. Magnetite is known to increase sensitivity of the biosensor. The combination of magnetite-polyethylene glycol (Fe3O4-PEG) was used to modify the surface of Screen-Printed Carbon Electrode modified (SPCE) and the resulting modified electrode (biofilm/Fe3O4/PEG/SPCE) displayed good electrocatalytic activity to the oxidation of UA. The composition of biofilms with optical density 1, magnetite 100 mgmL-1 and PEG 3% v / v were able to increase the current up to 48% in 4mM of UA. The biosensor with an optimum composition produced good linearity with a concentration range, limit of detection, limit of quantitation, sensitivity, and repeatability were found to be 0.1 - 4.3 mM, 70 µM, 234 µM, 25.392 µA mM-1, 2.38%, respectively. This biosensor stable up to 49 days of measurement with the remaining activity was 90.70% and selective for interference compounds such as salt, urea, glucose, ascorbic acid. This method has a good stability, sensitivity, and potential application in clinical analysis. Keyword: biofilm, biosensor, L. plantarum, magnetite, uric acid.
EFEKTIFITAS PENERAPAN METODE STRUCTURAL ANALITYCAL SYNTHETIC (SAS) DALAM MENINGKATKAN KETERAMPILAN MEMBACA PESERTA DIDIK KELAS I MI NURUL ISLAMIYAH KEMANG
Authors: Sela Nur , Baisa Hidayah , Suhandi Tjetjep 
Published: January 2019

AbstrakTujuan penelitian ini adalah untuk mengetahui efektifitas penerapan metode Structural Analitycal Synthetic (SAS) dalam meningkatkan keterampilan membaca. Penelitian ini dilaksanakan di kelas I MI Nurul Islamiyah Kemang. Penelitian dilakukan dalam tiga siklus setiap siklusnya terdiri dari empat tahap yaitu perencanaan (plan), pelaksanaan (act), observasi (observe), dan refleksi (reflect). Pengumpulan data yang dilakukan menggunakan tes, observasi dan dokumentasi yang dianalisis secara kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa metode Structural Analitycal Synthetic (SAS) efektif digunakan dalam pembelajaran membaca yang ditunjukkan oleh hasil observasi aktivitas guru dengan presentase siklus I = 65,28%, siklus II = 91,67%, dan siklus III = 100%. Hasil observasi aktivitas peserta didik dengan presentase siklus I = 74,44%, siklus II = 76,67%, dan siklus III 80%. Sementara peningkatan keterampilan membaca peserta didik diperoleh dari rata-rata hasil posttest, pra siklus = 68,14% dengan presentase ketuntasan 46,43%, siklus I = 77,53% dengan presentase ketuntasan 67,86%, siklus II = 87,11% dengan presentase ketuntasan 89,29%, dan siklus III = 91,39% dengan presentase ketuntasan 100% dari 28 peserta didik. Dengan demikian dapat disimpulkan bahwa metode structural analitycal synthetic (SAS) efektif digunakan dan dapat meningkatkan keterampilan membaca peserta didik kelas I MI Nurul Islamiyah KemangAbstract The purpose of this study was to know the effectiveness of applying Structural Analitycal Synthetic (SAS) method in improving reading skill. This research was conducted in grade I MI Nurul Islamiyah Kemang. Research done cycle each cycle consist of four stages of planning, action, observation, and reflection. Data collection conducted using test, observations and documentations that are analyzed qualitatively and quantitatively. The result of research indicate that Stuctural Analitycal Synthetic (SAS) method is effective used in reading learning which shown trhough observation result of teacher activity with the percentage of cycle I = 65,28%, cycle II = 91,67%, and cycle III = 100%. Observation result of students activities with percentage of cycle I = 74,44%, cycle II = 76,67%, and cycle III = 80%. While improving students reading skills is derived from the average post test result, pre cycle = 68,14% with a percentage of completeness 46,43%, cycle I = 77,53% with a percentage of completeness 67,86%, cycle II = 87,11% with a percentage of completeness 89,29%, and cycle III = 91,39% with a percentage of completeness 100% from 28 students. Thus it can be concluded that the Stuctural Analitycal Synthetic (SAS) method is effectively used and can improve the reading skills of first grade students of MI Nurul Islamiyah Kemang.
NEGARA HUKUM DAN PEMBANGUNAN NASIONAL BERWAWASAN HUKUM
Authors: Jumadi Jumadi 
Published: January 2019

The national development of legal insight is based on the principles of state law and legal insight that includes the development of the legal systen, the general draft of law policy, the implementation of law enforceable state, and the orientation of legal norms. The enforcement orientation must meet the requirements of legal material and law enforcement officers. Efforts to reform the material of national law must be in accordance with the needs of the times and in line with the development of the velues of community justice by socializing the material of national law through a real program and widely disseminated and suistainable so taht applicable legal norms are known, understood, recognized and accepted with awareness by every citizen.Keywords: State of Law, National Development, Legal Insight pembangunan nasional berwawasan hukum didasari oleh prinsip negara hukum dan wawasan hukum yang mencakup pembangunan sistem hukum, rancangan umum kebijakan hukum, penyelenggaran negara berwawasan hukum, dan orientasi norma hukum. Adapun orientasi penegakannya harus memenuhi syarat materi hukumnya dan aparat penegak hukum. Upaya pembaruan materi hukum nasional harus sesuai kebutuhan zaman dan sejalan dengan perkembangan nilai-nilai keadilan masyarakat dengan cara mensosialisasikan materi hukum nasional melalui suatu program nyata dan dimasyarakatkan secara luas dan berkesinambungan sehingga norma hukum yang berlaku diketahui, dimengerti, diakui, dan diterima dengan kesadaran oleh setiap warga negara.Kata Kunci: Negara Hukum, Pembangunan Nasional, Wawasan Hukum