bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constraints on magnetospheric radio emission from Y dwarfs
Authors: Kao Melodie M , Hallinan Gregg , Pineda J Sebastian 
Published: May 2019

Abstract
As a pilot study of magnetism in Y dwarfs, we have observed the three known infrared variable Y dwarfs WISE J085510.83−071442.5, WISE J140518.40+553421.4, and WISEP J173835.53+273258.9 with the NSF’s Karl G. Jansky Very Large Array in the 4–8 GHz frequency range. The aim was to investigate the presence of non-bursting quiescent radio emission as a proxy for highly circularly polarized radio emission associated with large-scale auroral currents. Measurements of magnetic fields on Y dwarfs may be possible by observing auroral radio emission, and such measurements are essential for constraining fully convective magnetic dynamo models. We do not detect any pulsed or quiescent radio emission, down to rms noise levels of 7.2 µJy for WISE J085510.83−071442.5, 2.2 µJy for WISE J140518.40+553421.4, and 3.2 µJy for WISEP J173835.53+273258.9. The fractional detection rate of radio emission from T dwarfs is ∼10 per cent suggesting that a much larger sample of deep observations of Y dwarfs is needed to rule out radio emission in the Y dwarf population. We discuss a framework that uses an empirical relationship between the auroral tracer Hα emission and quiescent radio emission to identify brown-dwarf auroral candidates. Finally, we discuss the implications that Y dwarf radio detections and non-detections can have for developing a picture of brown dwarf magnetism and auroral activity.
2StrucCompare: a webserver for visualizing small but noteworthy differences between protein tertiary structures through interrogation of the secondary structure content
Authors: Drew Elliot D , Janes Robert W 
Published: May 2019

Abstract
2StrucCompare is a webserver whose primary aim is to visualize subtle but functionally important differences between two related protein structures, either of the same protein or related homologues, with similar or functionally different tertiary structures. At the heart of the package is identifying and visualizing differences between conformations at the secondary structure and at the residue level, such as contact differences or side chain conformational differences found between two protein chains. The protein secondary structures are determined according to four established methods (DSSP, STRIDE, P-SEA and STICKS), and as each employs different assignment strategies, small conformational differences between the two structures can give rise to paired residues being denoted as having different secondary structure features with the different methods. 2StrucCompare captures both the large and more subtle differences found between structures, enabling visualization of these differences that could be key to an understanding of a proteins’ function.
2StrucCompare is freely accessible at http://2struccompare.cryst.bbk.ac.uk/index.php
Comparison of disease activity measures in early psoriatic arthritis in usual care
Authors: Wervers Kim , Luime Jolanda J , Tchetverikov Ilja , Gerards Andreas H , Kok Marc R , Appels Cathelijne W Y , van der Graaff Wiebo L , van Groenendael Johannes H L M , Korswagen Lindy-Anne , Veris-van Dieren Josien J , Hazes Johanna M W , Vis Marijn ,   for CICERO
Published: May 2019

AbstractObjectivesTo compare responsiveness and longitudinal validity of Disease Activity Score 28 (DAS28), Disease Activity index for PSoriatic Arthritis (DAPSA), Composite Psoriatic Disease Activity Index (CPDAI), Psoriatic ArthritiS Disease Activity Score (PASDAS), GRAppa Composite scorE (GRACE) and Minimal Disease Activity (MDA) in usual care PsA patients, within 1 year after diagnosis.MethodsData collected in the Dutch southwest early PsA cohort (DEPAR) were used. Responsiveness was assessed using effect size (ES), standardized response mean (SRM), and discrimination between different general health states. Longitudinal validity was tested using mixed models with outcomes health-related quality of life (HRQOL), productivity and disability.ResultsResponsiveness was highest for PASDAS, with ES 1.00 and SRM 0.95, lowest for DAPSA, with ES 0.73 and SRM 0.71, and in between for DAS28, CPDAI and GRACE. Differences in general health were best discriminated with PASDAS and GRACE. Patients reporting stable or worsening general health could not be distinguished by DAS28 or CPDAI. Discrimination was better using DAPSA, but worse than when using PASDAS and GRACE. Longitudinal evolvement of HRQOL and productivity had the highest association with low disease activity according to GRACE, followed by PASDAS, MDA, DAPSA, DAS28, with the lowest association for CPDAI.ConclusionPASDAS and GRACE were superior with respect to responsiveness, and together with MDA best related to longitudinal evolvement of HRQOL, productivity and disability. Responsiveness and longitudinal validity of most outcomes were inferior for DAS28, DAPSA and CPDAI. As alternatives to the continuous measure DAPSA, use of PASDAS or GRACE should be considered.
Low delta and high alpha power are associated with better conflict control and working memory in high mindfulness, low anxiety individuals
Authors: Jaiswal Satish , Tsai Shao-Yang , Juan Chi-Hung , Muggleton Neil G , Liang Wei-Kuang 
Published: May 2019

Abstract
Working memory capacity (WMC) can predict conflict control ability. Measures of both abilities are impaired by anxiety, which is often inversely linked with mindfulness. It has been shown that a combination of high mindfulness and low anxiety is associated with better conflict control and WMC. The current study explored the electrophysiology related to such behavioral differences. Two experimental groups, one with high mindfulness and low anxiety (HMLA) and one with low mindfulness and high anxiety (LMHA), performed a color Stroop task and a change detection task, both with simultaneous electroencephalogram (EEG) recording. An advanced EEG analytical approach, Hilbert–Huang transform (HHT) analysis, was employed. This is regarded as a robust method to analyze non-linear and non-stationary signals. Lower delta activity at posterior temporal and occipital regions was seen in the HMLA group for the Stroop conflict conditions and might be generally associated with higher accuracy in this group and indicative of higher attentiveness. Higher accuracy rates and WMC were seen in the HMLA group and might be specifically associated with the higher alpha activity observed in prefrontal cortex, fronto-central and centro-parietal regions in this group. Future studies should explore how mindfulness and anxiety can independently affect these cognitive functions and their associated neurophysiology.
The Carceral Creep: Gender-Based Violence, Race, and the Expansion of the Punitive State, 1973–1983
Authors: Kim Mimi E 
Published: May 2019

AbstractThe development of the feminist anti-domestic violence movement in the United States illustrates the trajectory from a social movement field devoid of carceral involvement to one fully occupied by the agents of crime control. Countering a narrative that often begins with the Violence against Women Act of 1994, this study demonstrates how the roots of carceral feminism extend back to the movement’s first decade from 1973 to 1983. This study analyzes data from 60 social movement leaders. The pluralist coalition resulting from a successful lawsuit against the Oakland Police Department, the creation of the victim witness program in San Francisco, and the development of the Community Coordinated Response in Duluth, Minnesota, represent mechanisms of engagement with law enforcement tied to innovative organizational forms. The process called the “carceral creep” describes how early social movement successes against an initially unresponsive criminal justice system evolved into collaborative relationships that altered the autonomy and constitution of initial social movement organizations. The creation of new organizational forms and their replication contributed to today’s carceral feminism. These developments were accompanied by persisting gender, race, and class tropes used to justify pro-criminalization strategies and obfuscate impacts on marginalized communities.
Abdominal Surgical Site Infection Incidence and Risk Factors in a Mexican Population
Authors: Guzmán-García Crystell , Flores-Barrientos Oscar I. , Juárez-Rojop Isela E. , Robledo-Pascual Julio C. , Baños-González Manuel A. , Tovilla-Záratee Carlos A. , Hernández-Díaz Yazmín , González-Castro Thelma B. 
Published: May 2019

ABSTRACT

OBJECTIVE:
To investigate possible predictors and prevalence of surgical site infections (SSIs) in a group of Mexican patients who underwent open abdominal surgery.

METHODS:
This retrospective study included all patients (N = 755) who underwent elective or emergency open abdominal surgeries from October 2011 to March 2012.

MAIN OUTCOME MEASURE:
Sociodemographic and clinical characteristics were collected through preoperative and postoperative examinations by the infection surveillance team. The relationship among variables (age, gender, body mass index, comorbidities, smoking habit, antimicrobial prophylaxis, hair removal, American Society of Anesthesiologists classification, type of operation, duration of operation, and SSI classification) was analyzed by odds ratio and χ
2 tests.

MAIN RESULTS:
Of the 755 patients, 91 (12%) suffered from SSI. Several variables were associated with SSI: American Society of Anesthesiologists classification (P = .001) and receiving preoperative prophylactic antimicrobials (P < .0001), among other factors. Isolated pathogens were mostly enterobacteria (60%).

CONCLUSIONS:
Surveillance plays an important role in the control and prevention of SSI. Providers must implement appropriate procedures to reduce SSI after abdominal surgery.
Do Uncivil Nursing Students Become Uncivil Nurses? A National Survey of Faculty
Authors: Luparell Susan , Frisbee Kristi 
Published: May 2019

Abstract

BACKGROUND
Faculty frequently express anecdotal concerns that poorly behaving nursing students will go on to behave poorly as licensed nurses. Unfortunately, no empirical evidence exists to support or refute these concerns.

AIM
The purpose of this study was to determine what knowledge faculty have of poorly behaving nursing students who also behaved poorly in subsequent practice.

METHOD
A cross-sectional, descriptive design using online survey methods was used to gather data from a national sample of nurse educators.

RESULTS
Approximately 37 percent of respondents reported having personal knowledge of a former poorly behaving student who went on to display poor behavior as a licensed provider; 71 percent reported that at least one student had graduated in the previous year whom they thought should not have graduated based on unprofessional behaviors.

CONCLUSION
Study findings provide troubling evidence that at least some poorly behaving students continue to demonstrate unprofessional behavior as licensed nurses.
Developing Authentic Leadership Voice: Novice Faculty Experience
Authors: Patterson Barbara J. , Dzurec Laura , Sherwood Gwen , Forrester D. Anthony 
Published: May 2019

Abstract

AIM
The aim of this study was to determine the perceptions of 14 novice nurse faculty of a 20-month experiential leadership academy on the leadership development.

BACKGROUND
Managing the complexities of nursing faculty roles requires significant leadership skills that often are hard won. Evidence suggests that leadership preparation to prepare nursing faculty through guided mentoring can enhance faculty recruitment, satisfaction, and retention.

METHOD
Participants completed open-ended questions about their experiences in Sigma Theta Tau International’s Nurse Faculty Leadership Academy.

RESULTS
Data analysis revealed a meta-theme of “Finding Authentic Leadership Voice.” Four subthemes emerged to shape the meta-theme: Identifying Inner Strengths and Areas for Improvement, Increasing Self-Confidence and Self-Awareness, Increasing Focus on Others, and Clarifying Aspirations for a Leadership Future.

CONCLUSION
Reflecting on their experiences, participants recognized changes in their leadership roles as they found an authentic voice that helped them persist and thrive amid the complexities of their faculty roles.
Beliefs and Experiences of Nurse Educators Regarding Changing Answers on Examinations
Authors: Blakeman John R. , Laskowski Pamela S. 
Published: May 2019

Abstract

AIM
The purpose of this study was to explore nurse educators’ beliefs and experiences regarding students changing answers on multiple-choice examinations.

BACKGROUND
Studies suggest that answer-changing behavior does not negatively affect academic performance and may actually have a positive impact, but published studies reporting nurse educators’ beliefs and experiences on this topic are limited.

METHOD
A mixed-methods approach, QUAN + Qual, was employed. A survey with closed- and open-ended questions was emailed to nurse educators in Illinois.

RESULTS
Of the 125 nurse educators who completed the survey, a majority held negative views of answer-changing behavior; many noted that their experiences with students had shaped their views.

CONCLUSION
Nurse educators in this sample held an overall negative view of this behavior, contrary to the overall body of evidence suggesting there is possible benefit in changing answers. Several reasons exist to explain the inconsistency observed.
Prior Learning Assessment in Nursing: An Accelerated Pathway to Degree Completion
Authors: Lee Shirleatha , Dapremont Jill 
Published: May 2019

Abstract
The purpose of this study was to identify RN-BSN students’ perceived satisfaction with the use of prior learning assessments (PLAs) and to examine graduation rates for students who utilized PLA in comparison to non-PLA users. Students were surveyed to examine satisfaction with PLA use; retrospective data were examined to determine graduation status by PLA option. A high percentage of students perceived PLA as flexible and affordable, and users had significantly higher graduation rates. The PLA option is highly associated with degree completion.
Intraoperative bone tunnel laceration affects integrity of arthroscopic transosseous rotator cuff repair with a tunneling device
Authors: Hirakawa Yoshihiro , Manaka Tomoya , Ito Yoichi , Ichikawa Koichi , Matsuda Yoshinobu , Shimizu Hayato , Nakamura Hiroaki 
Published: May 2019

Background:
We aimed to evaluate the functional outcomes, incidence of bone tunnel laceration, and bone tunnel morphology of transosseous arthroscopic rotator cuff repair (ARCR) with the Arthro-TunnelerTM.

Methods:
Between May 2012 and April 2013, patients with full-thickness tears who underwent transosseous ARCR with the Arthro-TunnelerTM and could be followed for a minimum of 2 yr were included in this retrospective study. Functional outcomes, cuff repair integrity, intraoperative bone tunnel laceration, and postoperative bone tunnel morphology were analyzed.

Results:
We retrospectively evaluated 42 consecutive patients (average age: 67.6 yr) who underwent transosseous ARCR. The mean active forward elevation, mean active abduction, mean Constant-Murley score, mean American Shoulder and Elbow Surgeon Score (ASES), and pain Visual Analogue Scale (VAS) improved from preoperative values of 127 degrees, 118 degrees, 50.3 points, 53.2 points, and 4.5 to 159 degrees, 160 degrees, 83.3 points, 78.5 points, and 1.7, respectively, at the final follow-up (P<0.001, P<0.01, P<0.001, P<0.001, P<0.001, respectively). The re-tear rate was 16.7%. The intraoperative bone tunnel laceration occurrence was 67.8% (61 tunnels). Bone tunnel laceration and re-tear were significantly correlated. We evaluated the morphology of 81 bone tunnels with MRI of 90 bone tunnels. Eight, 37, and 36 tunnels were L-shaped, curve-shaped, and straight-shaped, respectively.

Conclusions:
The clinical results of transosseous ARCR with the Arthro-TunnelerTM were significantly improved at a minimum of 2 yr of follow-up. However, patients older than 65 yr were at a high risk of developing bone tunnel laceration, which was associated with rotator cuff re-tear.
Clinical Consequences of Antibody Formation, Serum Concentrations, and HLA-Cw6 Status in Psoriasis Patients on Ustekinumab
Authors: De Keyser Eline , Busard Celine I. , Lanssens Sven , Meuleman Lieve , Hutten Barbara A. , Costanzo Antonio , van den Reek Juul M. , Zweegers Jeffrey , Lambert Jo , Spuls Phyllis I. 
Published: May 2019

Background:
Ustekinumab for the treatment of psoriasis is currently administered in a standard dosing regimen. However, some patients tend to benefit from alternative dosing regimens, a step toward personalized medicine.

Methods:
To investigate the role of ustekinumab serum concentrations, anti-ustekinumab antibodies [AUA] and HLA-Cw6 status as tools for optimizing ustekinumab treatment, a multicenter prospective cohort study was conducted at an academic hospital with affiliated nonacademic hospitals in Belgium (cohort 1) and 2 academic hospitals in the Netherlands (cohort 2 and 3). Patients with plaque-type psoriasis were eligible if treated with ustekinumab for ≥16 weeks. Serum samples and Psoriasis Area and Severity Index scores were obtained at baseline, week 16, 28, 40, 52, and/or ≥64 of ustekinumab treatment.

Results:
A total of 137 patients with 229 observations for serum concentrations and AUA and 61 observations for HLA-Cw6 status were included. Presence of AUA (prevalence of 8.7%) was significantly associated with a diminished clinical response (P = 0.032). The median ustekinumab trough concentration was 0.3 mcg/mL (<0.02–3.80). No differences in serum concentrations were observed between moderate to good responders and nonresponders (P = 0.948). Serum trough concentrations were not affected by methotrexate comedication. Prevalence of HLA-Cw6 positivity was 41% with no statistically significant difference in clinical response between HLA-Cw6–positive and HLA-Cw6–negative patients (P = 0.164).

Conclusions:
The presence of AUA was associated with treatment failure in this patient population; measurement of AUA may therefore be a candidate marker for personalized pharmacotherapy. The clinical utility of ustekinumab serum trough concentrations or HLA-Cw6 status determination remains less clear. Further exploration on the potential of measuring ustekinumab serum concentrations and other biomarkers in predicting therapy outcomes should be encouraged.
Safety of Long-Term Storage and Shipping of Prestripped, Prestained, and Preloaded Descemet Membrane Endothelial Keratoplasty Tissue
Authors: Hooton Jason , Kim Kyeong Hwan , Lentz Stephen I. , Hicks Nicholas , Jones Kayla , McCoy Kristen , Mian Shahzad I. 
Published: May 2019

Purpose:
The purpose of this study was to determine the safety of long-term storage and shipping of prestripped, prestained, and preloaded Descemet membrane endothelial keratoplasty (p3DMEK) grafts.

Methods:
A total of 33 cadaveric corneas were prestripped, prestained, and preloaded using modified Jones tube injectors as p3DMEK. The corneas were masked to groups that were prepared <9 hours (control), 48 hours, and 72 hours before unloading and analysis. The 48- and 72-hour tissues were shipped by airfreight on each day before arrival to simulate domestic and international shipping. The corneas were then stained using Calcein AM vital dye (Molecular Probes, Eugene, OR) and imaged using an inverted confocal microscope. Primary outcome measures were endothelial cell loss (ECL, %) and sustainability of staining. MetaMorph software (Molecular Devices, Downingtown, PA) was used to quantify ECL, and staining was evaluated subjectively using all-or-none rating.

Results:
There was no difference in the mean ECL for the control, 48-hour, and 72-hour groups, which were 25.1% ± 8.8%, 26.4% ± 17.5%, and 19.2% ± 11.5%, respectively (P = 0.45; Kruskal–Wallis test). In all tissues of each group, no loss of staining was identified at each time point of analysis.

Conclusions:
ECL in p3DMEK tissue prepared 48 and 72 hours in advance and shipped using standard methods is similar to that in p3DMEK tissue prepared on the same day. These findings support the safety of domestic and international shipping of p3DMEK grafts.
Comparison of Endobronchial Ultrasound–guided Transbronchial Needle Aspiration With Stylet Retracted Partially Versus Completely for Molecular Testing
Authors: Fernandez-Bussy Sebastian , Biswas Abhishek , Labarca Gonzalo , Jantz Michael A. , Mehta Hiren J. 
Published: May 2019

Background:
Endobronchial ultrasound–guided transbronchial needle aspiration (EBUS-TBNA) is considered to be the initial diagnostic modality for most patients with lung cancer. However, the optimal technique for maximizing yield continues to vary in the real-world setting.

Objectives:
To evaluate the diagnostic yield of EBUS-TBNA with capillary sampling compared with complete stylet removal for molecular testing.

Methods:
Retrospective study, data from patients between January to May 2017 with indication of EBUS-TBNA whom ancillary testing, that is, next-generation sequencing, anaplastic lymphoma kinase (ALK), and programed death ligand-1 (PD-L1) expression was reviewed. The yield of 2 techniques, stylet retracted halfway (group 1) versus complete retraction (group 2), was compared.

Results:
A total of 24/27 (88.88%) samples were adequate for next-generation sequencing analysis in group 1 and 21/23 (91.30%) in group 2. For other molecular analyses, 24/27 (88.88%) samples in group 1 and 20/23 (86.95%) samples in group 2 were adequate for ALK analysis. 23/27 (85.18%) samples for group 1 and 20/23 (86.95%) samples for group 2 were adequate for PD-L1 analysis. Positive expression of PD-L1>50% was achieved in 9/23 (39.13%) of group 1 and 5/20 (25%) of group 2. There was no statistical difference in the yield between the 2 groups.

Conclusion:
EBUS-TBNA using either capillary sampling or complete stylet removal are effective and has a high proportion of satisfactory results for ancillary testing.
Effects of Changes in ICU Bed Supply on ICU Utilization
Authors: Barbash Ian J. , Wallace David J. , Kahn Jeremy M. 
Published: May 2019

Background:
The availability of intensive care unit (ICU) beds may influence the demand for critical care. Although small studies support a model of supply-induced demand in the ICU, there is a paucity of system-wide data.

Objective:
The objective of this study was to determine the relationship between ICU bed supply and ICU admission in United States hospitals.

Research Design:
Retrospective cohort study using all-payer inpatient records from Florida, Massachusetts, New Jersey, New York, and Washington from 2010 to 2012, linked to hospital data from Medicare’s Healthcare Cost Reporting Information System.

Subjects:
Three patient groups with a low likelihood of benefiting from ICU admission—low severity patients with acute myocardial infarction and pulmonary embolism; and high severity patients with metastatic cancer at the end of life.

Measures:
We compared the risk-adjusted probability of ICU admission at hospitals that increased their ICU bed supply over time to matched hospitals that did not, using a difference-in-differences approach.

Results:
For patients with acute myocardial infarction, ICU supply increases were associated with an increase in the probability of ICU admission that diminished over time. For patients with pulmonary embolism, there was a trend toward an association between change in ICU supply and ICU admission that did not meet statistical significance. For patients with metastatic cancer, admission to hospitals with an increasing ICU supply was not associated with changes in the probability of ICU admission.

Conclusions:
Increases in ICU bed supply were associated with inconsistent changes in the probability of ICU admission that varied across patient subgroups.