bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flow-Simulation Model Improves Analysis of Perforated-Rock Cleanup and Productivity
Authors: Carpenter Chris 
Published: January 2019

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 190113, “Advanced Analysis of Cleanup and Productivity From Perforated Rocks Using Computational Fluid Dynamics,” by Rajani Satti, SPE, Stephen N. Zuklic, and Derek Bale, SPE, Baker Hughes, a GE company, and Nils Koliha, Andrew Fager, SPE, Gana Balasubramanian, Bernd Crouse, SPE, and David Freed, SPE, EXA, prepared for the 2018 SPE Western Regional Meeting, Garden Grove, California, USA, 22–27 April. The paper has not been peer reviewed.
Because of inherent complexities, understanding the characteristics of perforations in downhole environments is a significant challenge. Perforation-flow laboratories have been used to provide insight into cleanup and productivity mechanisms around perforation tunnels. In contrast to previous studies, the model presented in this work uses the perforation-flow laboratory, micro-computed-tomography (CT) and conventional CT imaging, and, most importantly, an advanced simulation approach to provide an accurate assessment of cleanup techniques and productivity. This full-scale 3D flow model accounts for realistic aspects of tunnel geometry, perforation damage, and blockages that impede flow.
Introduction
In recent years, numerical tools increasingly have been used in conjunction with experiments to provide better insight into the flow characteristics of perforated cores and perforated well-scale formations. Several numerical studies on perforation fluid flow have been conducted for core scale. However, comprehensive details relating to the modeling of perforation-zone damage and thickness, flow directionality, debris mechanisms, and implications for cleanup have not been studied in detail. In addition, most computational fluid dynamics (CFD) studies have used traditional Navier-Stokes-based solvers. In this study, the authors have used a commercially available flow-simulation software based on the lattice Boltzmann method (LBM) to calculate the complex flow and cleanup mechanisms around the perforation tunnel.
Lattice-based methods, an alternative to traditional CFD methods, track the advection and collisions of fluid particles on a computational grid. Because the average number of particles per grid cell far exceeds the computing power required to track them individually, the particles are grouped into an integer number of discrete velocities. LBM has been well validated and is in common use for many flow applications. The flow solver used here includes a turbulence model that is similar conceptually to the large-eddy simulation approach. The flow solver also includes a porous-media model that is used, in this study, to model the rock. The porous-media model invokes a Darcy-type pressure loss by applying a flow resistance determined from the known permeability of the rock. The resistance can include a viscous (linear) and an inertial (quadratic) term with respect to local velocity and can be made to vary spatially to model rock heterogeneity.
Winter Pea, Crimson Clover, and Hairy Vetch Planted in Mixture with Small Grains in the Southeast United States
Authors: Vann R. A. , Reberg‐Horton S.C. , Castillo M.S. , McGee R.J. , Mirsky S.B. 
Published: January 2019

Core IdeasLegume and small grain cover crops are combined in mixture to provide N fertility and weed suppression for the following cash crop.In environments where winter pea growth is not restricted by cold, winter pea can produce as much biomass in mixture with small grains as crimson clover and hairy vetch.Hairy vetch was the most competitive legume with the small grains across environments and restricted small grain biomass production.The variability in total biomass composition across environments in this study demonstrates the importance of site specific cover crop species selection and mixture seeding rate recommendations.Legume and small grain cover crop mixtures may simultaneously fix N and suppress weeds. Studies were conducted from 2015 to 2017 in Maryland and North Carolina to compare winter pea (Pisum sativumL.) to crimson clover (Trifolium incarnatum) and hairy vetch (Vicia villosaRoth) for cover crop use in mixture with small grains. Five winter pea genotypes, one crimson clover cultivar, and one hairy vetch cultivar were screened in mixture with barley (Hordeum vulgare), oats (Avena sativa), and wheat (Triticum aestivum). Cold injury of the pea genotypes in Maryland severely impacted pea biomass. Peas were able to recover from cold injury in North Carolina. A robustly growing small grain aided in legume cold tolerance in some environments. In the Coastal Plain environments, all legume genotypes generally contributed to at least 50% of mixture biomass production. In the Maryland and Piedmont environments, the small grain dominated the cover crop mixture. Oats were generally more competitive with the legume species than barley or wheat. In the North Carolina Coastal Plain and Piedmont, several winter pea genotypes produced as much biomass in mixture as crimson clover and hairy vetch. Hairy vetch was the most competitive legume with the small grains across environments. The variability in total biomass composition across environments in this study demonstrates the importance of site specific cover crop species selection and mixture seeding rate recommendations.
A Review of Soybean Yield when Double‐Cropped after Wheat
Authors: Santos Hansel Damaris Sulzbach , Schwalbert Rai A. , Shoup Douglas E. , Holshouser David L. , Parvej Rasel , Prasad P.V. Vara , Ciampitti Ignacio A. 
Published: January 2019

Core Ideas

Relative to full‐season soybeans, the double‐crop soybean yield gap is delayed and full‐season soybean yields improved.
As wheat yield improved, double‐crop soybean has lower probability of presenting greater yields than wheat.
Previous wheat yield, and soybean planting date and maturity groups influenced the attainable yield for double‐crop soybeans.
Soybean (Glycine Max L.) planted after wheat (Triticum aestivum L.) harvest in same season (double cropped [DC]) has the potential to increase productivity and sustainability. The objectives of this synthesis review were to (i) quantify attainable yield for DC soybean benchmarking against full‐season (FS) soybean; (ii) determine and build probabilistic response models on the effect of previous wheat productivity on DC soybean yields; and (iii) detect and rank factors influencing DC soybean yields via a decision inference tree analysis. A global database on DC soybean studies collected from 1976 to 2017 was divided into three data sets: (i) FS and DC soybean (n = 141 data points); (ii) wheat and DC soybean (n = 463); and (iii) production factors and DC soybean (n = 547). Analysis showed that the yield gap between FS and DC soybeans increased from ‐31 to 1160 kg ha−1 as FS yield improved from 1500 to 3000 kg ha−1. Even though the proportion of the variation accounted for wheat yields in the DC soybean/wheat yield ratio was low (R2 = 0.15), the probability of soybean yield being equal to wheat yield was 0, 20, 30, and 55% for wheat yields of ≥6, ≥4 and <6, ≥2 and <4, and <2 Mg ha−1. Inference tree analysis indicated that the major factor impacting success of the DC system was wheat yield followed by soybean planting date and maturity group.
The Importance of Problem Based Learning in Islamic Higher Education
Authors: Kholis Nur 
Published: January 2019

This article aims to explain the importance of applying the Problem Based Learning (PBL) method in Islamic Religious Colleges (PTKI). this study uses literature review. The results of the study indicate that PBL is a constructive learning method that uses problems as a trigger for the learning process. This method is important for students in Islamic higher education in constructing their own learning experiences and knowledge, to improve critical thinking skills, problem solving, train communication skills, and improve student learning outcomes. AbstrakArtikel ini bertujuan memaparkan tentang pentingnya penerapan metode Problem Based Learning (PBL) di Perguruan Tinggi Keagamaan Islam (PTKI). penelitian ini menggunakan kajian kepustakaan. Hasil penelitian menunjukkan bahwa PBL adalah metode pembelajaran konstruktivistik yang menggunakan masalah sebagai pemicu proses pembelajaran. Metode ini penting untuk mahasiswa di pendidikan tinggi Islam dalam mengkonstruk pengalaman belajar dan pengetahuan sendiri, untuk meningkatkan kemampuan berpikir kritis, pemecahan masalah, melatih keterampilan komunikasi, dan meningkatkan hasil belajar mahasiswa.
Islamic Education in Supporting De-radicalization: A Review of Islamic Education in Pondok Pesantren
Authors: Haryani Tiyas Nur , Amin Muhammad Ikhsanul , Arifah Nur Hidayatul , Husna Arina Mardhiyana 
Published: January 2019

This article present of the result of research about pondok pesantren (Islamic religious boarding school) education in confronting radicalism, focusing in researching the efforts of Pondok Pesantren Darusy Syuhadah in confronting radicalism. Collecting qualitative data through observation, documentation, and purposively sampled interviews. The result shows that pesantrens have a significant role in overcoming radicalism through its management of education model and curricula. Pondok Pesantren Darusy Syuhadah with Salaf education model build teaching and education to create generation of da’i (Islamic missionaries) and teachers of Islamic religion, so the curriculum prioritizes politeness and away from radicalism. AbstrakArtikel ini mempresentasikan hasil penelitian tentang pendidikan pondok pesantren dalam menghadapi radikalisme, memfokuskan pada upaya yang dilakukan pesantren Salaf di Pondok Pesantren Darusy Syuhadah dalam menghadapi radikalisme. Data kualitatif dikumpulkan melalui observasi, dokumentasi, dan wawancara purposive sampeling. Hasilnya menunjukkan bahwa pesantren memiliki peran yang signifikan dalam mengatasi radikalisme melalui pengelolaan model pendidikan dan kurikulumnya. Pondok Pesantren Darusy Syuhadah dengan model pendidikan Salaf membangun pengajaran dan pendidikan untuk menciptakan generasi da'i dan guru agama Islam, sehingga kurikulumnya mengutamakan kesantunan dan jauh dari radikalisme.
The Search For Islamic Studies Information Through Smartphones By Visual Impairments Disability
Authors: Hafiar Hanny , Subekti Priyo , Budiana Heru Ryanto 
Published: January 2019

This study will find out the pattern of information retrieval about Islamic studies carried out by visual impairments people. This study uses a case study method. Respondents in this study were Muslim women with disabilities in the rehabilitation complex of the blind Wiyataguna, Bandung. The results showed that people with visual impairments used narrative sounds on their mobile phones to capture narrative voice abilities that were arranged at high speed. At first they used standard speed settings, but when the skill of capturing audio through the sense of hearing increased, they set the pace of the narrative to be very fast, so that other people had difficulty listening to it.AbstrakPenelitian ini berusaha untuk mengetahui pola pengambilan informasi mengenai studi Islam yang dilakukan oleh orang yang mengalami gangguan penglihatan. Penelitian ini menggunakan metode studi kasus. Responden dalam penelitian ini adalah perempuan Muslim penyandang cacat yang berada di komplek rehabilitasi orang buta Wiyataguna, Bandung. Hasil penelitian menunjukkan bahwa orang-orang dengan gangguan penglihatan menggunakan suara naratif pada handphone untuk menangkap kemampuan suara naratif yang diatur dengan kecepatan tinggi. Pada mulanya mereka menggunakan pengaturan kecepatan standar, namun ketika keterampilan menangkap audio melalui indera pendengaran meningkat, mereka mengatur laju narasi menjadi sangat cepat, sehingga orang lain sulit untuk mendengarkannya.
Synthesis and characterization of an ionic liquid–carboxylic acid copolymer scale inhibitor and its scale inhibition performance
Authors: Zhang Wenlin , Li Gongwei , Jin Fei , Huo Yu , Sun Tengfei , Li Chunli 
Published: January 2019

AbstractA phosphorus-free scale inhibitor (ionic liquid–carboxylic acid copolymer) was successfully synthesized by the reaction of 1-sulfobutyl-3-vinylimidazolium hydrogen sulfate (SVIS) and acrylic acid (AA). The structure of the product was characterized by Fourier transform infrared spectroscopy (FTIR), hydrogen nuclear magnetic resonance (1H NMR) and carbon-13 nuclear magnetic resonance (13C NMR). Then the scale inhibition efficiency of 1-sulfobutyl-3-vinylimidazolium hydrogen sulfate-acrylic acid (SVIS-AA) copolymer against CaCO3 and CaSO4 was determined. The results indicated that SVIS-AA copolymer showed better scale inhibition efficiency than poly (acrylic acid) (PAA). After that, the effects of temperature and Ca2+ concentration on the scale inhibition efficiency against CaCO3 were studied. Results showed that when the temperature reached 90 °C, the scale inhibition efficiency could still remain 91% at a concentration of 18 mg L−1. When the concentration of Ca2+ reached 1,200 mg L−1, the scale inhibition efficiency could remain 70% at a concentration of 20 mg L−1. At last, the effect of SVIS-AA copolymer on the morphologies of CaCO3 and CaSO4 scale was studied by scanning electron microscopy (SEM) and X-ray diffraction (XRD).
Spatial distribution of physico-chemical parameters for groundwater quality evaluation in a part of Satluj River Basin, India
Authors: Chaudhry Akshay Kumar , Kumar Kamal , Alam Mohammad Afaq 
Published: January 2019

Abstract
The rising population, contamination and mismanagement of groundwater worldwide require sustainable management techniques and strategies to prevent misuse of groundwater resources especially in the semi-arid regions of the world. The aim of the present study is to assess the distribution of contaminants in groundwater at a spatial level by using a geostatistical method, namely ordinary kriging. For this, a physico-chemical parameter data set at 14 sampling locations for a period over 25 years was assessed. Three semi-variogram models, namely exponential, Gaussian and spherical, fitted well for the data set and were cross-validated using predictive statistics. Based on nugget/sill ratio, which characterizes the overall spatial dependence of water quality parameters, it was observed that, apart from nitrate, all the other parameters showed moderate to weak spatial dependence (i.e. total hardness), indicating significant influence of urbanization, fertilization and industrialization. Spatial distribution maps of all the parameters were generated. Concentration of most of the parameters reported high values in the northern region, while silicon dioxide and potassium recorded high values in the southern and central regions of the study area respectively. The study highlighted the depleting groundwater resources in various regions of the study area, indicating that the groundwater quality is in a declining state.
Antroponymic statement and anthropocentrism as a product of communicative speech strategies implementation (based on the English language)
Authors: Angaleva Maria Anatolyevna 
Published: January 2019

The article is devoted to the analysis of the realization of language strategies and tactics in the usage of antroponymic and anthropocentric statements, i.e. the statements containing the indication of the communicant’s features and the general features of a person. The examples from the English literature supporting the put forward ideas are analyzed in the article
Problems of national education: historical retrospective (on the example of I.D. Popko's activity)
Authors: Trofimenko Svetlana Vitalevna 
Published: January 2019

The difficulties of public education have not lost their relevance today. Vivid personalities served and serve as substantial support in the matter of education. This article raises the question of the development of public education in the Kuban region, as well as the influence of the outstanding enlightener Lieutenant General I.D. Popko on this process. Having conducted a historical analysis of the personal library of the Kuban figure, the authors define the goals, chronological and territorial frameworks of the educational activities of Ivan Diomidovich. The basis of the study was the catalog left by I.D. Popko in a noble house in the city of Stavropol, as well as in the work of I.V. Dubinin and I.G. Ivantsov «Materials for the bibliographic reconstruction of the catalog of the personal library of Ivan Diomidovich Popko» [8].
Exploration of Novel 5α-Reductase Inhibitors for Benign Prostatic Hyperplasia by 2D/3D QSAR, Cytotoxicity Pre-ADME and Docking Studies
Authors: Dhingra Richa , Malhotra Manav , Sharma Vivek , Bhardwaj T.R. , Dhingra Neelima 
Published: January 2019

Background:
5α-Reductase (5AR), an NADPH dependent enzyme, is expressed in most of
the prostate epithelial cells. By converting testosterone (T) into more potent androgen dihydrotestosterone
(DHT), it plays an important role in men physiology and represents an efficient therapeutic target
for androgen-dependent diseases. Over the last few years, significant efforts have been made in order to
develop 5AR inhibitors (5ARI) to treat Benign Prostatic Hyperplasia because of excessive production of
DHT.

Methods:
In the present study, 2D and 3D QSAR pharmacophore models have been generated for 5ARI
based on known IC50 values with extensive validations. The four featured 2D pharmacophore based PLS
model correlated the topological interactions (SsOHE-index); semi empirical (Quadrupole2) and physicochemical
descriptors (Mol. Wt, Bromines Count, Chlorines Count) with 5AR inhibitory activity, and
has the highest correlation coefficient (r2 = 0.98, q2 =0.84; F = 57.87, pred r2 = 0.88). Internal and external
validation was carried out using test and proposed set of compounds. The contribution plot of electrostatic
field effects and steric interactions generated by 3D-QSAR showed interesting results in terms
of internal and external predictability. The well-validated 2D PLS, and 3D kNN models were used to
search novel 5AR inhibitors with different chemical scaffold. The compounds were further sorted by
applying ADMET properties and in vitro cytotoxicity studies against prostate cancer cell lines PC-3.
Molecular docking studies have also been employed to investigate the binding interactions and to study
the stability of docked conformation in detail.

Results:
Several important hydrophobic and hydrogen bond interactions with 5AR lead to the identification
of active binding sites of 4AT0 protein in the docked complex, which include the gatekeeper residues
ALA 63A (Chain A: ALA63), THR 60 A (Chain A: THR60), and ARG 456 A (Chain A:
ARG456), at the hinge region.

Conclusion:
Overall, this study suggests that the proposed compounds have the potential as effective
inhibitors for 5AR.
Immune Checkpoint Inhibitors-related Rheumatic Diseases: What Rheumatologist Should Know?
Authors: Gediz Fusun , Kobak Senol 
Published: January 2019

:
Immune checkpoint inhibitors are revolutionized drugs for cancer immunotherapy in
the last years. The mechanism of action of CPIs including the limitation of the activation of Tcells,
and thus enhancing the self-immune response against tumour cells. Checkpointinhibitors(
CPIs) may dysregulate the immune system, resulting in some toxicities. These toxicities
or side effects are called Immune-related Adverse Events (IRAEs) that can potentially affect
any organ and tissue. Rheumatic diseases due to checkpoint inhibitors are also reported in
the literature. The spectrum of rheumatic manifestations are quite wide; the most common are
arthralgia/arthritis, myalgia/myositis, polimyalgia rheumatica, lupus, rheumatoid arthritis,
Sjögren’s syndrome. At the same time, these drugs can also cause an exacerbation of known
rheumatologic disease. Treatment approaches for developing rheumatic findings due to checkpoint
inhibitors should be multidisciplinary. There should be a close relationship between oncologists
who follow-up these patients and rheumatologists. The rheumatic manifestations
should be defined and treated early. In general, the musculoskeletal side effects are transient and
may regress after stopping CPIs. The most commonly used medications are corticosteroids. Immunosuppressive
drugs (HQ, MTX, anti-TNF-alpha, anti-IL-6) should be preferred when treatment
is unresponsive or as steroid-sparing agents.

:
The aim of this review was to evaluate the checkpoint inhibitors-related rheumatologic findings and
therapeutic strategies in light of recent literature data.
Aripiprazole Overdose and Transient 2:1 Second Degree Atrioventricular Block: Only A Coincidence?
Authors: Russo Lucia , Di Vincenzo Angelo , Rizzo Alessandro , Rossato Marco , Vettor Roberto 
Published: January 2019

Background:
Atypical antipsychotics, unlike traditional antipsychotics, are considered to
have limited cardiovascular side effects, but recent evidence drew attention to potential cardiac rhythm
disturbances during aripiprazole therapy. Prolonged QT-interval and increased heart rate were described
during treatment with therapeutic doses of aripiprazole, and some reports have even shown relevant
arrhythmias, such as ventricular trigeminy and supraventricular tachycardia, in patients treated
with this drug.

Case Report:
Here, we report a case of a young female who attempted suicide with aripiprazole overdose
presenting with a concomitant 2:1 second degree atrioventricular block. Little is known on the
cardiac toxicity of atypical antipsychotics in overdose: reporting this case description, far from establishing
direct causality.

Results and Conclusion:
We would promote further efforts to define the possible effects of the drug
on the cardiac conduction system, for a safer management of patients in clinical practice.