bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Note on a Recent Attempt to Prove the Irrationality of ζ(5)
Authors: Chen Keyu , He Wei , He Yixin , Huang Yuxiang , Li Yanyang , Tang Quanyu , Wu Lei , Xu Shenhao , Yang Shuo , Yu Zijun 
Published: December 2024

Recently, Shekhar Suman[1] made an attempt to prove the irrationality of \(\zeta(5)\). Unfortunately, the proof is not correct. In this note, we discuss the fallacy in the proof.
An internal iliac artery ligation technique for bleeding control in the placenta accreta spectrum disorder
Authors: Riu Deviana Soraya , Sunarno Isharyah , Pelupessy Nugraha , Bakri Syarif , Muchtar Faisal , Andi Adil  , Muhiddin Rachmawati 
Published: December 2024

Objective: To assess the contribution of internal iliac artery ligation to bleeding control during surgery.
Methods: This retrospective study used secondary data from medical records. All patients diagnosed with PASD from January 2019 – to December 2022 were included in this study. Participants were grouped based on operation technique, and the blood loss and operative duration were evaluated. The tests used were the Kruskal-Wallis and the Mann-Whitney U tests.
Results: 108 PAS patients were discovered. The most age group was between 20-35 years with parity of more than or equal to 4, history of Cesarean section once, gestational age at termination 34-36 weeks, and maternal death in 7 out of 101 cases. There were 49 resections, 13 resections with internal iliac artery ligation, 34 hysterectomies, and 12 hysterectomies with internal iliac artery ligation. There was no difference in bleeding and operative duration between resection vs. resection with internal iliac artery ligation (p: 0.113; p: 0.639), hysterectomy vs. a hysterectomy with internal iliac artery ligation ((p:0.052; P:0.723), and resection with ligation vs hystetectomy with the internal iliac artery ligation (p:0.052; p:0.723). Bleeding and operative duration differed significantly between resection vs. hysterectomy (p:0.002; p:0.013). All patients underwent tourniquet placement.
Conclusion An Internal iliac artery ligation was not shown to reduce bleeding in treating PASD.
Keywords: accreta, internal iliac artery, placenta .
Epidemiology of Cervix Uteri Cancer in Saudi Arabia from 2004 to 2017
Authors: Alghamdi Ibrahim 
Published: December 2024

Abstract:
Objectives: This study investigates the epidemiological pattern of Cervix Uteri cancer (CUC) throughout all administrative regions of Saudi Arabia. It examines the frequency number and percentage of diagnosed cases, the age-specific incidence rate (AIR), the crude incidence rate (CIR), and the age-standardized incidence rate (ASIR) stratified by age group, year of diagnosis, and regions.
Methods: A retrospective descriptive epidemiological investigation of all CUC cases documented in the Saudi Cancer Registry (SCR) between 2004 and 2017 was performed. Statistical Package for the Social Sciences, version 20.0, was utilized to analyse the data using descriptive statistics and the Kruskal-Wallis test (SPSS).
Results: In total, 1,451 UCU diagnosed cases were reported to the SCR between January 2004 and December 2017. Northern, Eastern, and Tabuk regions had the highest ASIR of CUC among Saudi women (2.2, 2.0, and 2.0 per 100,000 women). In contrast, among Saudi women, Jazan had the lowest overall ASIR of CUC (0.7 per 100,000 women, respectively).
Conclusion: The ASIRs of CUC in Saudi Arabia decreased slightly from 2004 to 2017. The Northern, Eastern, and Tabuk regions of Saudi Arabia had the highest ASIR of CUC among Saudi women, while women in Jazan, Saudi Arabia, were proven to be the least affected by CUC.

Keywords: Cancer epidemiology; Cervix Uteri cancer; Saudi Cancer Registry; oncology; Incidence rate.
Atypical Findings of Suspect Twin to Twin Transfusion Syndrome Quintero V: a Rare Case Report
Authors: Gusasih Bahar Sangkur , Irianti Setyorini , Aziz Muhammad Alamsyah , Kurniadi Andi 
Published: December 2024

Introduction: Twin-to-twin transfusion syndrome (TTTS) is a serious complication in monochorionic multiple pregnancies.
Case Illustration: A-38 years old woman with G3P2AO felt 8 months pregnant and came for polyclinic control with the diagnosis of G3P2A0 gravida 34-35 weeks; Gemelli; Baby I Breech position; Baby I Polyhydramnios, IUFD; Suspected Twin Twin Transfusion Syndrome (TTTS Quintero V). However, atypical findings of TTTS are rarely found and should be taken as special notes such in this case. We will report a rare finding of TTTS in which the SDP level of the donor fetus was normal (not oligohydramnios). The suspected diagnosis of TTTS Quintero V in this case was made clinically based on the maternal-fetal ultrasound findings of a diamniotic monochorionic gemelli pregnancy with IUFD in the 2nd fetus II. However, there were non-standard findings in this case where the SDP level of the donor fetus was normal (not oligohydramnios). No other sequele complications were found in this case based on other examinations.
Conclusions: Several therapies are available for TTTS including amnioreduction, laser ablation of the vascular placental anastomosis, selective feticide, and septostomy. Timing of delivery after management of singleton fetal death in the late second or early third trimester is debatable. Delivery method is determined based on obstetric indications.
The value of intrapartum ultrasound in predicting mode of delivery: A prospective cohort study
Authors: Omar Gamal , Marwa F Sharaf  , Mohammad A. Taymour  
Published: December 2024

Abstract
Objectives: Ultrasound contributes significantly to management of labor, delivery and prevention of adverse maternal and fetal outcomes. Among many suggested intra-partum ultrasound parameters, the use of transperineal ultrasound scan to assess the angle of progression (AoP) and levator hiatus anteroposterior diameter (APD) has been suggested to result in a more objective evaluation of labor progress. The aim of this study was to assess this claim.
Methods: This was a prospective observational cohort study involving primparous term singleton vertex presentation pregnant patients >18 years old admitted in the first stage of labor between January 2021 and May 2023. All patients provided an informed written consent. This investigation utilized both transabdominal and transperineal ultrasonography for comprehensive fetal and pelvic floor assessment. Transabdominal ultrasound evaluated standard parameters including fetal occiput position, biometry number, viability, presentation, and estimated fetal weight. Intrapartum transperineal ultrasonography, specifically performed during the first stage of labor, focused on the Levator Hiatus, measuring its anteroposterior diameter (APD) at rest and during Valsalva maneuver, as well as the angle of progression (AOP).
Results: The study population comprised 609 participants with a mean age of 22.8 ± 4.3 years and a high prevalence of being overweight and obesity (38.8% and 57.8%, respectively). When comparing patients who had an intrapartum CS to those who had a normal vaginal delivery (NVD). However, on logistic regression, age, BMI, gestational age, posterior occiput presentation, head circumference (HC), AOP (V) and APD (V) as significant predictors for both ICS and 2nd stage CS (p<0.05).
Conclusion: This study demonstrated that maternal age, BMI, gestational age, occiput posterior position, Angle of progression at Valsalva and levator hiatus anteroposterior diameter at Valsalva were independent significant predictors for Intrapartum cesarean section in primiparous women at term When the ratio between HC/APD at rest, BPD/APD at Valsalva and HC/APD at Valsalva is high, while the APD at Valsalva, AoP Valsalva values are low, cesarean section was more likely to be the mode of delivery.
Keywords: Intrapartum ultrasound, angle of progression, anteroposterior diameter of levator hiatus, mode of delivery, intrapartum cesarean section.
Magmatic evolution and architecture of an oceanic intraplate volcano: Vesteris Seamount, Atlantic Ocean
Authors: Beloša L. , Murphy D. T. , Ubide T. , Callegaro S. , Meyzen C. M. , Bizimis M. , Mazzini A. 
Published: December 2024

Vesteris is a large (33 × 27 km) and young (summit age: 0.65–0.010 Ma) intraplate seamount in the Greenland Sea, formed from ocean island basalt (OIB) magmatism. The volcano is composed of alkali basalt, basanite/tephrite, phonotephrite, mugearite, and benmoreite. Its phenocryst assemblage includes clinopyroxene, plagioclase, olivine, amphibole, rare haüyne, and oxides (Ti–magnetite and Cr–spinel), with phenocrysts hosting inclusions of apatite, sulfides (pyrrhotite), and melt. Despite its geological significance, the processes governing magma storage, ascent, and eruption dynamics remain poorly understood. To address this, we conducted detailed micro–chemical analyses of phenocrysts, groundmass microcrysts, melt inclusions, and groundmass glass. Using mineral–melt thermobarometry, we characterized the pre– to syn–eruptive crystallization conditions and reconstructed the architecture of the volcanic plumbing system. Our findings indicate that basanite liquids were primarily stored in the upper mantle (∼6.4 kbar; ∼22 km depth) with evidence of multi-level storage extending to ∼9 kbar (∼30 km depth). Textural and compositional zoning in clinopyroxenes suggests rapid magma ascent, while mafic recharge emerged as a key mechanism for remobilizing evolved clinopyroxene mush. Mafic recharge magmas also introduced early olivine crystals, which were later overgrown by high-Mg clinopyroxene upon mixing with more evolved melts. These results demonstrate that major crystal fractionation occurs in the upper mantle beneath Vesteris, resembling processes observed in low-flux ocean island basalt volcanoes. The evidence for rapid magma ascent highlights the dynamic nature of magma movement within the plumbing system, driven by mafic recharge and crystal-melt interactions.
Evaluation of the peripheral visual performance of DIMS spectacle lenses versus single vision lenses
Authors: Liu Kenneth Ka King , Zhang Han Yu , Leung Daisy Ka Yan , Lam Carly Siu Yin 
Published: December 2024

PurposeThis study evaluates differences in the visual field performance when wearing the Defocus Incorporated Multiple Segments (DIMS) spectacle lens compared to wearing a conventional single vision (SV) spectacle lens.MethodsTwenty-one children aged 9–14 years with spherical equivalent refraction (SER) between −1.13D to −4.75D were recruited. Mid-peripheral near visual acuity (NVA) under room lighting condition (500 lux ±10%) was measured using DIMS and SV lenses, respectively. Automated static perimetry (Zeiss, Humphrey Visual Field HFA 750i) with SITA Fast 30–2 protocol was used to investigate the visual field sensitivity. During the test, the study lens (Plano DIMS or SV lens) were inserted into the lens holder in front of the trial lenses with each child’s compensated prescription.ResultsThree children were not able to complete the reliable visual tests due to fixation losses (&gt;20%) or high false positive rate (&gt;15%) while 18 children successfully completed the test. The mean visual field sensitivity was 29.2 ± 3.7 decibels (dB) and 29.3 ± 3.5 dB when wearing DIMS and SV lens, respectively. The mean sensitivity differences between DIMS and SV lens among 76 locations ranged from −2.4 ± 3.9 dB to 1.6 ± 3.9 dB. No statistically significant difference in sensitivity was observed across 76 locations within the central 30o between DIMS and SV lens (Wilcoxon signed rank test with bonferroni correction for multiple comparisons, p &gt; 0.00065). Compared to SV lens, 0.05 logarithm of minimal angle of resolution (logMAR) reduction in mid-peripheral NVA in all 4 quadrants (Superior, Temporal, Inferior and nasal, p &lt; 0.05) was noted with the DIMS lens (N = 18). However, no statistically significant correlation was found between the mid-peripheral NVA and visual sensitivity at the specific locations.ConclusionAlthough the mid-peripheral NVA was slightly reduced using DIMS lens, wearing DIMS lens did not change the children’s visual sensitivity to detect the static stimulus within 30o visual field when compared to wearing SV lens.
The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses
Authors: Barnette Dustyn , Inselman Amy L. , Kaldhone Pravin , Lee Grace S. , Davis Kelly , Sarkar Sumit , Malhi Pritpal , Fisher J. Edward , Hanig Joseph P. , Beger Richard D. , Jones E. Ellen 
Published: December 2024

IntroductionIn 2015, the FDA released a Drug Safety Communication regarding a possible link between opioid exposure during early pregnancy and an increased risk of fetal neural tube defects (NTDs). At the time, the indications for opioid use during pregnancy were not changed due to incomplete maternal toxicity data and limitations in human and animal studies. To assess these knowledge gaps, largescale animal studies are ongoing; however, state-of-the-art technologies have emerged as promising tools to assess otherwise non-standard endpoints. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a dynamic approach capable of generating 2D ion images to visualize the distribution of an analyte of interest across a tissue section.MethodsGiven the importance of lipid metabolism and neurotransmitters in the developing central nervous system, this study incorporates MALDI MSI to assess lipid distributions across mouse gestational day (GD) 18 fetuses, with and without observable NTDs following maternal exposure on GD 8 to morphine (400 mg/kg BW) or the NTD positive control valproic acid (VPA) (500 mg/kg BW).ResultsAnalysis of whole-body mouse fetuses revealed differential lipid distributions localized mainly in the brain and spinal cord, which included several phosphatidylcholine (PC) species such as PCs 34:1, 34:0, and 36:2 localized to the cortex or hippocampus and lyso PC 16:0 across all brain regions. Overall, differential lipids increased in with maternal morphine and VPA exposure. Neurotransmitter distributions across the brain using FMP-10 derivatizing agent were also assessed, revealing morphine-specific changes.DiscussionThe observed differential glycerophospholipid distributions in relation to treatment and NTD development in mouse fetuses provide potential targets for further investigation of molecular mechanisms of opioid-related developmental effects. Overall, these findings support the feasibility of incorporating MALDI MSI to assess non-standard endpoints of opioid exposure during gestation.
Assessing Roles of Aggregate Structure on Hydraulic Properties of Saline/Sodic Soils in Coastal Reclaimed Areas
Authors: Fei Yuanhang , She Dongli , Tang Shengqiang , Wang Hongde , Sun Xiaoqin , Han Xiao , Liu Dongdong 
Published: December 2024

During coastal reclamation processes, land use conversion from natural coastal saline/sodic soils to agricultural land changes the soil’s physicochemical properties. However, the impact of soil structure evolution on soil hydraulic properties (SHPs, e.g., hydraulic conductivity and soil water retention curves) during long-term reclamation has rarely been reported. In this study, we aimed to evaluate the effect of reclamation duration and land use types on the soil aggregate stability and SHPs of coastal saline/sodic soils and incorporate the aggregate structures into the SHPs. In this study, a total of 90 soil samples from various reclaimed years (2007, 1960, and 1940) and land use patterns (cropland, grassland, forestland, and wasteland) were taken to analyze the quantitative effects of soil saline/sodic characteristics and the aggregate structure on SHPs through pedotransfer functions (PTFs). We found that soil macroaggregate contents in the old reclaimed areas (reclaimed in 1940 and 1960) were significantly larger than those in the new reclamation area (reclaimed in 2007). The soil saturated hydraulic conductivity (Ks) of forestland was larger than that of grassland in each reclamation year. Soil structure contributed to 22.13%, 24.52%, and 23.93% of the total variation in Ks and soil water retention parameters (α and n). The PTFs established in our study were as follows: log(Ks) = 0.524 − 0.177 × Yk3 − 0.093 × Yk1 + 0.135 × Yk4 − 0.054 × Yk2, 1/α = 477.244 − 91.732 × Yα2 − 81.283 × Yα4 + 38.106 × Yα3, and n = 1.679 − 0.086 × Yn2 + 0.045 × Yn1 − 0.042 × Yn3 (Y are principal components). The mean relative errors of the prediction models for log(Ks), 1/α, and n were 79.30%, 36.1%, and 9.89%, respectively. Our findings quantify the vital roles of the aggregate structure on the SHPs of coastal saline/sodic soils, which will help us understand related hydrological processes.
Mathematical Modeling of Salmonella Inactivation During Apple Drying and Pre-Drying Heating in Closed Environments
Authors: Yang Ren , Zhang Shuang , Tang Juming 
Published: December 2024

Drying is one of the most effective preservation methods for extending the shelf-life of perishable foods. The microbial safety of low-moisture food products had not been recognized as a concern until outbreaks reported over the past decade in products contaminated with bacterial pathogens, in particular Salmonella. There is now an urgent need to understand the influence of process conditions on the thermal inactivation of pathogens in various drying operations. This study aimed to develop a predictive model for Salmonella inactivation in diced apples during hot air drying and in high-humidity heating in closed environments. Fresh-cut apple cubes (6 mm) inoculated with a cocktail of Salmonella enterica strains (Enteritidis PT30, Montevideo 488275, and Agona 447967) were placed in a customized box inside an oven for three different treatments: (1) open-box drying at oven temperature 90 °C (Drying-90); (2) close-box pre-drying heating at 90 °C (PD heating-90); and (3) close-box pre-drying heating at 70 °C (PD heating-70). Air temperature, relative humidity (RH), and sample temperatures were monitored, and Salmonella survival was measured at multiple time intervals. After 10 min, the air RH reached 66% in PD heating-90 and 74% in PD heating-70, versus 30% in Drying-90. A 5-log reduction in Salmonella was achieved in 8.5 min in PD heating-90, and 14 min in PD heating-70, compared to 28.7 min in Drying-90. A mathematical model using sample surface RH and sample temperature profiles accurately predicted Salmonella inactivation across all treatments (RMSE = 0.92 log CFU/g, R2 = 0.86), with thermal death parameters comparable to isothermal studies. This study underscores the role of humidity in enhancing microbial reduction during drying and proposes high-humidity pre-drying heating as an effective control step. The developed model shows promise for real-time prediction of microbial inactivation in complex drying environments with dynamic temperature and humidity conditions.
d-Xylitol Production from Sugar Beet Press Pulp Hydrolysate with Engineered Aspergillus niger
Authors: Knesebeck Melanie , Rüllke Marcel , Schönrock Veronika , Benz J. Philipp , Weuster-Botz Dirk 
Published: December 2024

d-Xylitol is a low-calorie and anti-cariogenic sweetener suitable for diabetic patients, making it a valuable ingredient in various health-related applications. In this study, we investigated the production of d-xylitol from l-arabinose derived from sugar beet press pulp (SBPP) hydrolysate using an engineered Aspergillus niger strain. Initial batch studies applying stirred tank bioreactors demonstrated d-xylitol production of 4.6 g L−1 with a yield of 0.37 g d-xylitol g−1 l-arabinose with a synthetic medium. Subsequently, the conversion of enzymatically produced and clarified SBPP hydrolysate was studied. We found that pre-treatment of the enzymatic hydrolysate with activated carbon was essential to remove inhibitory components. Moreover, an automated aeration switch-off was implemented based on the CO2 signal of the off-gas analyzer of the stirred tank bioreactor to prevent d-xylitol degradation after l-arabinose depletion. This resulted in a final d-xylitol concentration of 4.3 g L−1 with an improved yield of 0.43 g d-xylitol g−1 l-arabinose. The feasibility of utilizing the agricultural residue SBPP for d-xylitol production was successfully demonstrated with engineered A. niger.
Cardiovascular risk estimation and statin adherence: an historical cohort study protocol
Authors: Finnikin Samuel , Willis Brian , Khatib Rani , Evans Tim , Marshall Tom 
Published: December 2024

BackgroundAdherence to statins for the primary prevention of cardiovascular disease (CVD) is low. There is evidence that some facets of the initiation consultation, or the initiating clinician, are associated with adherence. CVD risk estimation is fundamental to statin initiation and shared decision making (SDM), because the benefits of statins are proportional to CVD risk. Absence of a recorded CVD score before statin initiation therefore indicates SDM is unlikely.AimTo investigate whether SDM, using CVD risk score as a proxy measure, is associated with adherence to statins and CVD outcomes.Design & settingA retrospective cohort study using a database of English primary care records.MethodThe cohort will include statin naïve patients aged 40-84 years initiated on statins for primary prevention between 2017 and 2020, categorised by the presence or absence of a CVD risk score at statin initiation. Statin adherence and persistence will be determined from subsequent statin prescriptions. Multivariable modelling, accounting for potential confounders, will determine the association between a recorded CVD risk score and subsequent statin adherence and with statin persistence. A secondary analysis will investigate the relationship to subsequent CVD outcomes and death.ConclusionThis research uses a record of CVD risk score as a proxy for SDM, to investigate the link between SDM and medication adherence. It will shed light on relationship between how the initiation consultation is performed and subsequent adherence and persistence with treatment.
Объяснение и пониманиев социально-гуманитарном познании
Authors: ВАСИЛЬЕВ В.А. 
Published: December 2024

В статье анализируются объяснение и понимание в социально-гуманитарном познании. Выделяются гносеологические уровни, формы проявления объяснения, понимания, интерпретации, смысла.
The article analyzes the explanation and understanding in social and humanitarian cognition. Epistemological levels, forms of explanation, understanding, interpretation, meaning are distinguished.
Повышение роли женщин в президентских выборах в США
Authors: ИРХИН Ю.В. 
Published: December 2024

В статье проанализировано возрастание роли гендерного фактора в современных электоральных процессах в Соединенных Штатах Америки. Показаны причины актуализации гендерного фактора в связи с увеличением числа женщин и активизации их участия в политике.
The article analyzed the increasing role of the gender factor in modern electoral processes in the United States of America. Showed reasons of the actualization of the gender factor related to the increase in the number of women and activation of their participation in politics.
Проблемы внедрения технологий четвертой промышленной революции в России (по материалам книги К. Шваба)
Authors: МЕЛЬКОВ С.А. , МАЛЕКА Ю.Н. , ЛЯБАХ А.Ю. 
Published: December 2024

В статье на основании книги К. Шваба проводится анализ проблем внедрения технологий четвертой промышленной революции на территории РФ.
Based on the book by K. Schwab, the article analyzes the problems of introducing technologies of the fourth industrial revolution on the territory of the Russian Federation.