bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatial prediction of groundwater spring potential mapping based on an adaptive neuro-fuzzy inference system and metaheuristic optimization
Authors: Khosravi Khabat , Panahi Mahdi , Tien Bui Dieu 
Published: September 2018

Abstract. Groundwater is one of the most valuable natural resources in the world (Jha
et al., 2007). However, it is not an unlimited resource; therefore
understanding groundwater potential is crucial to ensure its sustainable use.
The aim of the current study is to propose and verify new artificial
intelligence methods for the spatial prediction of groundwater spring
potential mapping at the Koohdasht–Nourabad plain, Lorestan province, Iran.
These methods are new hybrids of an adaptive neuro-fuzzy inference system
(ANFIS) and five metaheuristic algorithms, namely invasive weed optimization
(IWO), differential evolution (DE), firefly algorithm (FA), particle swarm
optimization (PSO), and the bees algorithm (BA). A total of 2463 spring
locations were identified and collected, and then divided randomly into two
subsets: 70 % (1725 locations) were used for training models and the
remaining 30 % (738 spring locations) were utilized for evaluating the
models. A total of 13 groundwater conditioning factors were prepared for
modeling, namely the slope degree, slope aspect, altitude, plan curvature,
stream power index (SPI), topographic wetness index (TWI), terrain roughness
index (TRI), distance from fault, distance from river, land use/land cover,
rainfall, soil order, and lithology. In the next step, the step-wise
assessment ratio analysis (SWARA) method was applied to quantify the degree
of relevance of these groundwater conditioning factors. The global
performance of these derived models was assessed using the area under the
curve (AUC). In addition, the Friedman and Wilcoxon signed-rank tests were
carried out to check and confirm the best model to use in this study. The
result showed that all models have a high prediction performance; however,
the ANFIS–DE model has the highest prediction capability (AUC = 0.875),
followed by the ANFIS–IWO model, the ANFIS–FA model (0.873), the ANFIS–PSO
model (0.865), and the ANFIS–BA model (0.839). The results of this research
can be useful for decision makers responsible for the sustainable management
of groundwater resources.
Continental soil drivers of ammonium and nitrate in Australia
Authors: Lee Juhwan , Garland Gina M. , Viscarra Rossel Raphael A. 
Published: September 2018

Abstract. Soil
N is an essential element for plant growth, but its mineral forms are subject
to loss from the environment by leaching and gaseous emissions. Despite its
importance for the soil-plant system, factors controlling soil mineral N
contents over large spatial scales are not well understood. We used
NH4+ and NO3- contents (0–30 cm depth) from
469 sites across Australia and determined soil controls on their regional
variation. Soil mineral N varied regionally but depended on the different
land uses. In the agricultural region of Australia, NH4+ tended
to be similar (median 4.0 vs. 3.5 mg N kg−1) and NO3-
was significantly enriched (3.0 vs. 1.0 mg N kg−1), compared to the
non-agricultural region. The importance of soil controls on mineral N in the
agricultural region, identified by the model trees algorithm Cubist, showed
that NH4+ was affected by total N, cation exchange capacity
(CEC) and pH. In the non-agricultural region, NH4+ was affected
not only
by CEC and pH, but also by organic C and total P. In each of the regions,
NO3- was primarily affected by CEC, with more complex
biophysical controls. In both regions, correlations between mineral N and
soil C : N : P stoichiometry suggest that more NH4+ was
found in P-depleted soil relative to total C and total N. However, our
results showed that only in the non-agricultural region was NO3-
sensitive to the state of C and its interaction with N and P. The models
helped to explain 36 %–68 % of regional variation in mineral N. Although
soil controls on high N contents were highly uncertain, we found that
region-specific interactions of soil properties control mineral N contents.
It is therefore essential to understand how they alter soil mechanisms
and N cycling at large scales.
Na naturalisatie is er niet zonder meer sprake van een zuiver interne situatie voor het personenverkeer
Authors: Oosterom-Staples H. 
Published: September 2018

Na naturalisatie is er niet zonder meer sprake van een zuiver interne situatie voor het personenverkeer
De Algerijnse Toufik Lounes vraagt bij de Britse autoriteiten een verblijfskaart ‘derdelander familielid van een Unieburger’ aan. Zijn aanvraag wordt afgewezen, omdat zijn echtgenote naast de Spaanse ook de Britse nationaliteit bezit; er is sprake van een interne situatie waarop het Unierecht niet ziet. Het Hof van Justitie oordeelt anders. Omdat zijn vrouw de Britse nationaliteit heeft verkregen na uitoefening van haar reis- en verblijfsrecht en met behoud van haar oorspronkelijke nationaliteit valt haar situatie en daarmee ook die van haar familieleden binnen de werkingssfeer van het Unierecht. Haar derdelander echtgenoot ontleent zijn verblijfsrecht aan het Unierecht dat tevens de voorwaarden bepaalt waaronder dit recht mag worden uitgeoefend.HvJ EU 14 november 2017, zaak C-165/16, Toufik Lounes/Secretary of State for the Home Department, ECLI:EU:C:2017:862.
Differential expression of NF-κB heterodimer RelA/p50 in human urothelial carcinoma
Authors: Durairajan Sankari , Jebaraj Walter Charles Emmanuel , Samuel Mary Divya , Palani Dinesh , G Dicky John Davis , C George Priya Doss , Pasupati Sneha , Johnson Thanka 
Published: September 2018

Background
Urothelial carcinoma (UC) is the fifth most common malignancy that accounts for 5% of all cancers. Diagnostic markers that predict UC progressions are inadequate. NF-κB contributes towards disease progression upon constitutive activation in many solid tumors. The nuclear localization of NF-κB indicates increased transcriptional activity while cytoplasmic localization indicates the inactive protein repository that can be utilized readily by a malignant cell. This study delineates the nuclear and cytoplasmic differential expression of NF-κB heterodimers in UC progression.

Methods
The involvement of the NF-κB proteins in UC was analyzed in silico using cytoscape. The expression of NF-κB heterodimers was analyzed by immunohistochemistry.

Results
PINA4MS app in cytoscape revealed over expression of RelA and suppression of NF-κB1 (p50 precursor) in UC whereas the expression of NF-κB target proteins remained unhindered. Immunohistochemical localization showed nuclear RelA/p50 in low grade UC whereas in high grade only RelA expression was observed. Conversely, cytoplasmic expression of RelA/p50 remained extensive across high and low grade UC tissues (p < 0.005). RelA nuclear and cytoplasmic expression (p < 0.005) was directly proportional to the disease progression. In our study, some of the high-grade UC tissues with squamous differentiation and muscle invasion had extensive nuclear p50 localization. The phenomenon of RelA/p50 expression seen increased in low-grade UC than high grade UC might be due to their interaction with other members of NF-κB family of proteins. Thus, NF-κB RelA/p50 differential expression may play a unique role in UC pathogenesis and can serve as a biomarker for diagnosis.
Double‐Shelled Phosphorus and Nitrogen Codoped Carbon Nanospheres as Efficient Polysulfide Mediator for High‐Performance Lithium–Sulfur Batteries
Authors: Wang Jin , Yang Hao , Chen Zhen , Zhang Lili , Liu Jilei , Liang Pei , Yang Hui , Shen Xiaodong , Shen Ze Xiang 
Published: September 2018

AbstractLithium–sulfur batteries are regarded as very promising energy storage devices due to their high energy density, low cost, and environmental friendliness; however, their insulating properties and the instability of sulfur‐based electrodes impede the practical applications of Li–S batteries. Here, a versatile strategy to synthesize double‐shelled nitrogen and phosphorus codoped carbon spheres (NPDSCS) as an efficient sulfur host for Li–S batteries is reported. With strong trapping, good affinity, high adsorption for polysulfides, and the bifunctional catalyzing for sulfur redox processes, the developed NPDSCS cathodes with a high S loading of 72.4% exhibit large specific discharge capacity of 1326 mAh g−1 at 0.1C, high Coulombic efficiency, good rate capability, and excellent cycling performance with a reversible capacity of 814 mAh g−1 at 1C after 500 cycles.
Plasma Amyloid as Prescreener for the Earliest Alzheimer Pathological Changes
Authors: Verberk Inge M. W. , Slot Rosalinde E. , Verfaillie Sander C. J. , Heijst Hans , Prins Niels D. , van Berckel Bart N. M. , Scheltens Philip , Teunissen Charlotte E. , van der Flier Wiesje M. 
Published: September 2018

ObjectiveWe investigated the association of plasma amyloid beta (Abeta)40, Abeta42, and total tau (tTau) with the presence of Alzheimer pathological changes in cognitively normal individuals with subjective cognitive decline (SCD).MethodsWe included 248 subjects with SCD (61 ± 9 years, 42% female, Mini‐Mental State Examination = 28 ± 2) from the SCIENCe project and Amsterdam Dementia Cohort. Subjects were dichotomized as amyloid abnormal by cerebrospinal fluid (CSF) and positron emission tomography (PET). Baseline plasma Abeta40, Abeta42, and tTau were measured using Simoa technology. Associations between plasma levels and amyloid status were assessed using logistic regression analyses and receiver operating characteristic analyses. Association of plasma levels with risk of clinical progression to mild cognitive impairment (MCI) or dementia was assessed using Cox proportional hazard models.ResultsFifty‐seven (23%) subjects were CSF‐amyloid abnormal. Plasma Abeta42/Abeta40 ratio and plasma Abeta42 alone, but not tTau, identified abnormal CSF‐amyloid status (plasma ratio: area under the curve [AUC] = 77%, 95% confidence interval [CI] = 69–84%; plasma Abeta42: AUC = 66%, 95% CI: 58–74%). Combining plasma ratio with age and apolipoprotein E resulted in AUC = 83% (95% CI = 77–89%). The Youden cutoff of the plasma ratio gave a sensitivity of 76% and specificity of 75%, and applying this as a prescreener would reduce the number of lumbar punctures by 51%. Using PET as outcome, a comparable reduction in number of PET scans would be achieved when applying the plasma ratio as prescreener. In addition, low plasma ratio was associated with clinical progression to MCI or dementia (hazard ratio = 2.0, 95% CI = 1.4–2.3).InterpretationPlasma Abeta42/Abeta40 ratio has potential as a prescreener to identify Alzheimer pathological changes in cognitively normal individuals with SCD. Ann Neurol 2018;84:656–666
Influence of novel X‐ray imaging technology on radiation exposure during chronic total occlusion procedures
Authors: Busse Tilmann , Reifart Joerg , Reifart Nicolaus 
Published: September 2018

AbstractObjectivesWe assessed whether use of the novel X‐ray imaging technology AlluraClarity (Philips Healthcare, Best, The Netherlands) results in a meaningful reduction of radiation exposure for patients during coronary intervention on chronic total occlusions (CTO‐PCI) compared to its predecessor Allura Xper (Philips Healthcare, Best, The Netherlands).BackgroundPercutaneous coronary intervention on chronic total occlusion causes 2‐ to 10‐fold higher radiation burden on patients and operators compared to standard PCI. To avoid iatrogenic damage to our patients and personnel, all efficient ways to reduce radiation should be identified and implemented.MethodsRadiation exposure of 196 consecutive CTO patients treated in the same laboratory by a single experienced operator (total experience: > 2,500 CTOs, annual experience: > 100 CTOs/year) was analyzed. Ninety‐eight CTO‐PCIs (n1) were performed with the Allura Xper system and 98 patients (n2) were treated using AlluraClarity.ResultsThe two groups had similar BMI (n1: mean 28.43 kg/m2; n2: mean 28.41 kg/m2), procedure duration (n1: mean 75.9 min; n2: mean 70.7 min), and J‐CTO scores (n1: mean 2.99; n2: mean 2.82). The success rates did not differ (n1: 86/98 successful). n2: 87/98 successful). The radiation doses, however, revealed significant differences in kerma area product (KAP; absolute reduction of 34%; n1: mean 61.5 Gycm2; n2: mean 40.8 Gycm2; P < 0.002) and cumulative air kerma (AK; absolute reduction of 30%; n1: mean 966.8 mGy; n2: mean 675.9 mGy; P < 0.002).ConclusionUse of the novel X‐ray imaging technology resulted in a meaningful and significant reduction in patient radiation exposure during complex coronary interventions (CTO‐PCI) compared to use of its predecessor. Similar success rates support the operator's subjective impression of similar, and in some cases superior, image quality.
Fenestrated ASD device “angioplasty”: How to adjust a “pop‐off” mechanism when needed
Authors: Tufaro Vincenzo , Butera Gianfranco 
Published: September 2018

AbstractWe report on three cases of atrial septal defect (ASD) closure where a handmade fenestration had to be modified after device implantation. Two patients suffered from left ventricular diastolic dysfunction and one had severe pulmonary arterial hypertension. Amplatzer ASD occluder fenestration was created in all patients. Devices were implanted using an “over‐the‐wire” implantation technique. Due to a sub‐optimal hemodynamic result, fenestration was upsized by using a new technique.
Emergency trans‐catheter coronary intervention for left main compression secondary to pulmonary hypertension in a 4‐year‐old child
Authors: Butera Gianfranco , Mansour Nizar Ben , De Marco Federico 
Published: September 2018

AbstractHere, we report on the case of a 4‐year‐old child with large atrial septal defect (ASD) and severe pulmonary hypertension presenting an ischemic cardiomyopathy secondary to left main (LM) compression by a dilated pulmonary artery trunk. Despite of surgical treatment consisting in ASD closure and coronary artery bypass grafting, the patient was not weanable from ECMO. Control coronarography showed a near‐occlusion of the left mammary bypass. A rescue percutaneous LM angioplasty with drug‐eluting stent implantation was performed.
Valve‐in‐valve‐in‐valve: Balloon expandable transcatheter heart valve in failing self‐expandable transcatheter heart valve in deteriorated surgical bioprosthesis
Authors: Schaefer Andreas , Deuschl Florian , Conradi Lenard , Schäfer Ulrich 
Published: September 2018

AbstractValve‐in‐valve (ViV) procedures for failing bioprostheses carry a certain risk for device malfunction. We herein report a case of a failing Evolut R in a deteriorated Mitroflow, treated with a Sapien 3.An 81 year old female patient received surgical aortic valve replacement and was treated by ViV due to deterioration. Three years later, echocardiography revealed a pressure gradient of peak/mean 105/63 mmHg. Subsequently, a second ViV procedure with initial intentional rupture of the bioprosthetic stent was performed. Immediate stent recoil of the Evolut R prompted implantation of a Sapien 3. In 30‐day follow‐up, mean pressure gradient of 30 mmHg and nearly complete symptom relief was documented.Fracture of a surgical bioprosthetic stent is feasible in a ViV configuration. Supra‐annular placement of a balloon‐expandable THV as ViV‐in‐valve is feasible with suboptimal hemodynamic results in this case. Risk of re‐do surgery should be weighted against anticipated hemodynamic and clinical results.
Contrast volume to estimated glomerular filtration rate ratio for prediction of contrast‐induced acute kidney injury after cardiac catheterization in adults with congenital heart disease
Authors: Gellis Laura , Gauvreau Kimberlee , Ferguson Michael , Bergersen Lisa , Shafer Keri , Porras Diego 
Published: September 2018

AbstractBackgroundAdults with congenital heart disease (ACHD) are vulnerable to contrast‐induced acute kidney injury (CI‐AKI) after cardiac catheterization. The aim of this study was to identify risk factors for clinically significant CI‐AKI and evaluate the predictive value of contrast volume to estimated glomerular filtration rate ratio (V/eGFR) for the risk of CI‐AKI following catheterization in the ACHD population.MethodsACHD patients who underwent catheterization at Boston Children's hospital between 1/2011 and 1/2017 were retrospectively analyzed. CI‐AKI was defined as an increase in serum creatinine ≥0.3 mg/dL within 48 hr or ≥1.5 times baseline within 7 days of procedure. Controls without CI‐AKI were matched for calendar year of catheterization with cases using a 3:1 ratio.ResultsOf 453 catheterizations meeting inclusion criteria, 27 catheterizations (5.9%) were complicated by CI‐AKI, with dialysis being used to manage renal dysfunction in five of these events. Older age, male gender, admission prior to catheterization, and V/eGFR ratio were found to be related to risk of CI‐AKI. Patients with a V/eGFR ≥ 2.6 had a significantly higher risk of CI‐AKI (OR = 6.4; 95% CI = 2.0–20.4; P = 0.002). Survival at 3 years post‐catheterization, was significantly shorter for CI‐AKI cases compared to controls (49% versus 97%; P < 0.001) even in those with return to baseline renal function prior to discharge (60% versus 97%, P < 0.001).ConclusionIn ACHD patients undergoing cardiac catheterization, a higher V/eGFR ratio is a strong predictor of clinically significant CI‐AKI. Development of CI‐AKI is a poor prognostic indicator and is associated with decreased survival in this population.
Premounted stents for branch pulmonary artery stenosis in children: A short term solution
Authors: Ooi Yinn Khurn , Kim Sung In H. , Gillespie Scott E. , Kim Dennis W. , Vincent Robert N. , Petit Christopher J. 
Published: September 2018

AbstractObjectiveDefine outcomes of premounted stent implantation (PMS) for branch pulmonary artery stenosis (BPAS).BackgroundPMS for BPAS in children raises concern of long term viability, with limited maximal expansion.MethodsWe reviewed our cardiac database over an 11‐year period ending in 2013. Primary endpoint was need for surgical stent intervention (SSI). Other endpoints included acute results and repeat interventions (RI).Results82 PMS were implanted in 60 children for BPAS. Median weight was 6.3 (25th‐75th 4.6–9.8) kg. Median stent diameter was 6 (range 4–9) mm. Acutely, vessel diameter improved from 2.0 (25th‐75th 1.6–3.4) to 5.0 (25th‐75th 4.2–5.9) mm (p < 0.001), pressure gradient decreased from 41 (25th‐75th 29–50) to 11 (25th‐75th 7–18) mmHg (n = 47, p < 0.001), RV:Ao pressure ratio decreased from 100% (25th‐75th 85–110%) to 59% (25th‐75th 49–74%) (n = 40, p < 0.001). Freedom from SSI was 81% at 1 year and 35% at 5 years. Freedom from RI was 50% at 1 year and 14% at 5 years. 86% of PMS underwent SSI during a concomitant planned cardiac surgery. 45% patients had stent redilation, improving stent diameter from 4.6 (25th‐75th 4.1–5.4) to 5.7 (25th‐75th 4.9–7) mm (p < 0.001). 1 stent (3%) was able to be fractured longitudinally.ConclusionsPMS is an effective short term solution for BPAS in children. PMS is associated with expected early need for transcatheter reintervention to accommodate for growth, but also has high rates of SSI.
Coronary intervention and arteria lusoria—Not simple as it may seem
Authors: Rafiq Arsalan , Chutani Surendra , Krim Nassim R. 
Published: September 2018

AbstractWe reviewed the letter from Dr. Walter W. Woody and would like to thank him for showing his interest in our article and providing his opinion and point of view. However, we respectfully disagree with few points that have been raised. Switching to a femoral approach was considered to be a safer alternative for percutaneous intervention due to the presence of arteria lusoria. Risks and possible complications would include increased contrast use, increased radiation exposure, aortic dissection and even cerebral stroke, all of which have been reported extensively in literature. One single procedural methodology cannot be applied to a particular clinical scenario, whether simple or challenging. We have multiple different catheters and multiple different interventional approaches at our disposal to help and guide us through a case, in the best interest of the patient.
Transfemoral aortic valve implantation following lithoplasty of iliac artery in a patient with poor vascular access
Authors: Gorla Riccardo , Cannone Gaspare Sergio , Bedogni Francesco , De Marco Federico 
Published: September 2018

AbstractTransfemoral approach is considered the preferred route to perform transcatheter aortic valve implantation (TAVI) by most operators due to the low invasiveness and good outcome, as compared to non‐transfemoral approach. However, transfemoral access is not always feasible particularly in patients with small and calcific vessels. Recently, catheter‐based lithoplasty has emerged as a new technique based on the use of circumferential pulse pressure waves to disrupt calcific plaques. This technology may help to expand eligibility for transfemoral TAVI to patients with calcific ileo‐femoral vessels and at high risk for non‐transfemoral approach. We present the case of an 87‐year‐old woman with poor vascular access who successfully underwent transfemoral TAVI following lithoplasty of iliac artery.
Use of Amplatzer vascular plugs and Amplatzer duct occluder II additional sizes for occlusion of patent ductus arteriosus: A multi‐institutional study
Authors: VanLoozen Dennis , Sandoval Juan Pablo , Delaney Jeffrey W. , Pedra Carlos , Calamita Paulo , Dalvi Bharat , Kenny Damien , Cleary Aoife , Amin Zahid 
Published: September 2018

AbstractBackgroundVariable patent ductus arteriosus (PDA) morphology and the need to close PDAs in small size patients has led physicians to use Amplatzer Vascular Plugs (AVP) and recently available Amplatzer Duct Occluder II ‐ Additional Sizes (ADO II AS). The purpose of this study was to analyze the safety, efficacy, and complication rates of the ADO II AS and AVPs, specifically AVP II.MethodsAll patients undergoing PDA closure with an AVP or ADO II AS from 2011 to 2016 were included. Clinical, echocardiographic, and angiographic data were collected and reviewed.ResultsFour hundred and sixty‐nine patients were included. Median age was 27 months (0.75–852) and the median weight was 11.4 kg (1–92). There were 51 patients ≤5 kg. Type A PDA was most common in 48% (n = 225), followed by type E (27.5%, n = 129), type D (13%, n = 61), type C (10.2%, n = 48), and type B (1.3%, n = 6). Devices included AVP II (n = 421), ADO II AS (n = 30), and AVP IV (n = 18), left pulmonary artery stenosis occurred in 4.3% (n = 20). One patient required surgery for severe stenosis; the remaining cases were mild and required no intervention. Device embolization occurred in 3 patients (10%) with the ADO II AS. Successful device closure was achieved in 98.9% of cases.ConclusionsThe AVP II was highly effective for closing PDAs in smaller babies with varying morphologies and is safe when used in small sized patients with relatively low risk of complications. More studies are warranted to clarify the risks of ADO II AS.