bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scientific-Practical Approach to Revitalization Urban Environment of an Existing Single-Industry Town
Authors: Savostenko V A 
Published: June 2019

Abstract
The research method is aimed at solving the problems of a particular place of settlement and through this to design a key solution to solve the problems of settlement as a whole. The article gives an example of study and development of tools on the revitalization of the urban environment and related facilities in an existing single-industry town. In accordance with temporary, economic, territorial and other factors, principles of revitalization close to urban acupuncture have been developed. During the course of study, five stages of the town revival were proposed. Each stage involves the increase in the radius of the study and the impact on the urban environment. Programs of the stages could be general, but rather individual. Each stage has its own program and result. The strict adherence to each stage of the program gives a better result. And finally the five-stage approach makes it possible to achieve the prosperous, dynamic and sustainable settlement with the well-being town life.
Introduction of Gerontology Into Undergraduate Nursing Curricula: An Innovative Approach Utilizing a Collaborative Partnership for Clinical Nursing Education
Authors: Hunter Amy 
Published: June 2019

Abstract
The focus of this article is an innovative approach to teaching gerontology by utilizing a collaborative approach to structuring clinical experiences. The goal was to better prepare future nurses for the growing epidemic of baby boomers. Faculty were challenged to rethink clinical education and design a new method to better prepare nursing students to care for older adults.
Analyzing Use of the Graduate Record Examinations® General Test in Doctoral Nursing Education: Start, Stop, Continue, or Modify?
Authors: Chicca Jennifer 
Published: June 2019

Abstract

AIM
The purpose of this study was to analyze uses of the Graduate Record Examinations® (GRE) General Test in doctoral nursing education.

BACKGROUND
Doctoral study is a costly (time, money, resources, effort) investment for both students and institutions alike, and it is imperative students who are likely to succeed are admitted. Admission criteria such as the GRE General Test must be examined for appropriate use and necessity.

METHOD
Literature regarding uses of the GRE General Test in doctoral nursing education was analyzed versus GRE General Test publisher evidence-based uses and guidelines while considering test psychometrics.

RESULTS
Although the GRE General Test is widely used in doctoral nursing program admissions, it appears it is often not used according to evidence-based guidelines or uses. Notably, crucial self-validations are infrequent.

CONCLUSION
Self-validations are essential when determining if doctoral nursing programs should start, stop, continue, or modify their use of the GRE General Test. Admission criteria analyses may help streamline admission processes and remove some unnecessary costs in doctoral education.
Differences in Psychomotor Skills Teaching and Evaluation Practices in Undergraduate Nursing Programs
Authors: Kemery S. R. , Morrell Briyana L. M. 
Published: June 2019

Abstract

AIM
The purpose of this study was to understand the methods faculty use to teach and evaluate psychomotor skill performance in associate and baccalaureate nursing programs, resources available to students to master these skills, and policies and procedures related to summative evaluation of psychomotor skills.

BACKGROUND
Despite the importance of psychomotor skills competency in registered nursing programs, published methods for teaching and evaluating competency vary. The literature does not support a particular strategy for teaching or evaluation.

METHOD
In this primarily quantitative descriptive study, participants completed a 28-item questionnaire developed by the authors based on a review of the literature and personal teaching experience.

RESULTS
All respondents indicated that their institutions conducted summative assessment of psychomotor skills; however, the methods for teaching and evaluation varied widely.

CONCLUSION
Well-designed control studies and consensus guidelines from professional nursing education organizations would assist faculty in implementing consistent, effective, evidence-based strategies.
The Sandbox: Development and Implementation of a Technology-Enhanced Classroom
Authors: Logan Rebecca M. , Johnson Cynthia E. , Worsham Jeremy 
Published: June 2019

Abstract
Based on the call to transform nursing education, many nursing programs have begun to integrate more active learning strategies into the traditional classroom setting. Many educators have found successful integration requires an improved learning space that allows students to interact and work collaboratively. This article discusses a new innovative trend in higher education called the active learning classroom (ALC), how one college developed an ALC, and the impact of the ALC on the use of active learning strategies and student learning outcomes in the nursing education department.
A National Study Across Levels of Nursing Education: Can Nurses and Nursing Students Accurately Estimate Their Knowledge of Evidence-Based Practice?
Authors: Wonder Amy Hagedorn , Spurlock Darrell 
Published: June 2019

Abstract

AIM
This national study sought to: a) describe the evidence-based practice (EBP) knowledge levels of nursing students enrolled in baccalaureate through doctorate of nursing practice programs; b) examine relationships between objective and subjective EBP knowledge measures; c) describe correlations between educational and demographic factors and EBP knowledge; and d) further evaluate validity and reliability evidence for the Evidence-Based Practice Knowledge Assessment in Nursing.

BACKGROUND
Rigorous evaluation of students’ EBP knowledge across nursing program levels is vital to enhancing education and patient care.

METHOD
A cross-sectional, correlational design using large-scale survey procedures was used in this study.

RESULTS
Mean Evidence-Based Practice Knowledge Assessment in Nursing scores (N = 674 respondents from five universities in the United States) increased with greater levels of nursing education degree attainment. A weak, positive correlation was found between objective and subjective EBP knowledge measures (r = .13, p = .001).

CONCLUSION
More research is needed to identify effective approaches to EBP education in nursing programs.
Learning Together: Combining Undergraduate and Graduate Simulated Learning for Practicing Physical Assessment Skills
Authors: Schams Kristin , Snyder Audrey , Zeller Dean , Caywood Krisinda 
Published: June 2019

Abstract
The effectiveness of using undergraduate nursing students (UNS) as standardized patients for advanced practice nurses (APNs) was studied. First-semester UNS, as part of their health assessment course requirements, participated in APN students’ practice and testing sessions as standardized patients for their health assessment course physical exam. Analysis of pre/post experience scores and open-ended questions demonstrated UNS perceived confidence increased in 15 of 21 areas and APN students’ confidence increased in three areas. The collaborative examination process aided students in their learning of the process of the physical examination.
Office-based ocular procedures for the allergist
Authors: Leonardi Andrea , Borghesan Franco , Scalora Tania , Modugno Rocco Luigi , Bonaldo Alex 
Published: June 2019

Purpose of review
The aim of this study is to suggest principles for ocular procedures to be performed by allergists in their offices in helping their diagnosis of ocular diseases and suggest better interactions between allergists and ophthalmologists.

Recent findings
Diagnosis of ocular allergy is based on clinical history and signs and symptoms, with the support of in-vivo and in-vitro tests for the identification of the specific allergen. Unfortunately, ocular manifestations are frequently misdiagnosed and not properly managed.

Summary
A multidisciplinary allergist–ophthalmologist approach may improve early differential diagnosis and the prognosis of patients with allergic disease and conjunctivitis through shared management and earlier etiological treatment.
Underdosing of Prophylactic Enoxaparin Is Common in Orthopaedic Trauma and Predicts 90-Day Venous Thromboembolism
Authors: Jones Daniel L. , Jones William A. , Fleming Kory I. , Higgins Thomas F. , Rothberg David L. , Zhang Yingying , Pannucci Christopher J. 
Published: June 2019

Objectives:
To determine the feasibility and impact of real-time anti-factor Xa (aFXa) level monitoring and enoxaparin dose adjustment in orthopaedic trauma. To examine the adequacy of standard fixed-dose enoxaparin chemoprophylaxis and to examine whether patient-specific factors influence enoxaparin metabolism.

Design:
Prospective cohort.

Setting:
Academic Level-I trauma center.

Patients:
Postoperative adult orthopaedic trauma patients undergoing acute fracture or nonunion surgery of the pelvis, acetabulum, or lower extremity placed on 30 mg of enoxaparin twice daily.

Intervention:
Peak steady-state aFXa levels were drawn with a goal range of 0.2–0.4 IU/mL. Patients with out-of-range levels underwent a 10-mg dose adjustment followed by repeat aFXa draws.

Main Outcome Measures:
Peak and trough aFXa levels, 90-day venous thromboembolism, and bleed events.

Results:
Of 109 enrolled patients, 43% had inadequate initial peak aFXa levels (aFXa < 0.2 IU/mL) with standard dosing. Higher gross weight, acetabular surgery, and operation length predicted low aFXa levels (P < 0.001, 0.006, 0.004, respectively). Dose adjustment increased the proportion of patients with in-range aFXa levels from 53.2% to 87.8% (P < 0.001). Patients with low aFXa levels during hospitalization or at discharge had significantly higher 90-day deep vein thrombosis and pulmonary embolism rates compared to those with adequate aFXa levels (deep vein thrombosis 12% vs. 1.36%; P = 0.023, pulmonary embolism 8% vs. 0%; P = 0.027). There were no major bleed events.

Conclusions:
Patients receiving inadequate enoxaparin chemoprophylaxis were at significantly increased risk of 90-day venous thromboembolism. Standard fixed-dose enoxaparin provided inadequate chemoprophylaxis in 43% of postoperative orthopaedic trauma patients, which significantly improved with dose adjustment. Weight, acetabular surgery, and operation length predicted inadequate enoxaparin prophylaxis.

Level of Evidence:
Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.
Improving outcomes in patients with prediabetes through a lifestyle modification program
Authors: Daftarian Zahra , Bowen Pamela G. 
Published: June 2019

ABSTRACT

Background and purpose:
Type 2 diabetes and obesity are prevalent throughout the United States, and they occur at even higher rates in some southern states. This project aimed at improving outcomes for overweight/obese patients with prediabetes, thus reducing their risk of progression to type 2 diabetes.

Methods:
Twenty-four adults with a diagnosis of prediabetes and body mass index ≥ 25 completed this 3-month program. The Rapid Eating Assessment for Patients (REAPs) tool was used to assess eating habits and physical activity levels. The Single-Item Literacy Screener was used to screen for limited reading ability. The following preintervention and postintervention data were obtained: weight, A1c, REAP score, and REAP Physical Activity question (REAP-PA).

Intervention:
Monthly group educational sessions were conducted followed by individualized goal setting. The content of the sessions encompassed a lifestyle modification program based on the first five sessions of the Centers for Disease Control and Prevention “Prevent T2”curriculum, incorporating the Southern-style diet, food choices, and activity resources available in the local community.

Results:
Results revealed a significant (p < 0.05) decrease in weight (average 4.0 ± 4.2 kg), REAP score (average 17.6 ± 16.6), and REAP-PA (average 0.6) after intervention. A1c values decreased slightly but were not statistically significant, which may be due to the limited sample size. Those with limited reading ability showed a slightly greater A1c loss than those with adequate literacy.

Conclusions:
A 3-month lifestyle modification program resulted in improvement in weight, eating habits, physical activity level, and A1c in overweight/obese patients at risk for type 2 diabetes.
Medical resource utilization and costs for intraoperative and early postoperative periprosthetic hip fractures following total hip arthroplasty in the medicare population
Authors: Chitnis Abhishek Shirish , Mantel Jack , Vanderkarr Mollie , Putnam Matthew , Ruppenkamp Jill , Holy Chantal Elisabeth , Bridgens Joshua 
Published: June 2019

Abstract
This study assessed the impact of intraoperative and early postoperative periprosthetic hip fractures (PPHFx) after primary total hip arthroplasty (THA) on health care resource utilization and costs in the Medicare population.
This retrospective observational cohort study used health care claims from the United States Centers for Medicare and Medicaid Standard Analytic File (100%) sample. Patients aged 65+ with primary THA between 2010 and 2016 were identified and divided into 3 groups – patients with intraoperative PPHFx, patients with postoperative PPHFx within 90 days of THA, and patients without PPHFx. A multi-level matching technique, using direct and propensity score matching was used. The proportion of patients admitted at least once to skilled nursing facility (SNF), inpatient rehabilitation facility (IRF), and readmission during the 0 to 90 or 0 to 365 day period after THA as well as the total all-cause payments during those periods were compared between patients in PPHFx groups and patients without PPHFx.
After dual matching, a total 4460 patients for intraoperative and 2658 patients for postoperative PPHFx analyses were included. Utilization of any 90-day post-acute services was statistically significantly higher among patients in both PPHFx groups versus those without PPHFx: for intraoperative analysis, SNF (41.7% vs 30.8%), IRF (17.7% vs 10.1%), and readmissions (17.6% vs 11.5%); for postoperative analysis, SNF (64.5% vs 28.7%), IRF (22.6% vs 7.2%), and readmissions (92.8% vs 8.8%) (all P < .0001). The mean 90-day total all-cause payments were significantly higher in both intraoperative ($30,114 vs $21,229) and postoperative ($53,669 vs $ 19,817, P < .0001) PPHFx groups versus those without PPHFx. All trends were similar in the 365-day follow up.
Patients with intraoperative and early postoperative PPHFx had statistically significantly higher resource utilization and payments than patients without PPHFx after primary THA. The differences observed during the 90-day follow up were continued over the 1-year period as well.
Comparison of early postoperative recovery between laryngeal mask airway and endotracheal tube in laparoscopic cholecystectomy
Authors: Kang Se Hee , Park MiHye 
Published: June 2019

Abstract

Background:
Laryngeal mask airway (LMA) insertion provokes fewer stress responses than endotracheal intubation. This study aimed to evaluate the LMA Protector for assessing improvements in intraoperative hemodynamic stability and to reduce postoperative discomfort compared with endotracheal intubation in laparoscopic cholecystectomy.

Methods:
Fifty-six patients who underwent laparoscopic cholecystectomy while under sevoflurane-based general anesthesia were randomly allocated to airway management using LMA (LMA group) or endotracheal tube (ETT group). Heart rate, blood pressure, and peak airway pressure were recorded before and after carboperitoneum. Postoperative pain and analgesic requirements were assessed, in addition to nausea, hoarseness, dysphonia, and sore throat during the first 1 hour postoperatively and until postoperative day 1.

Results:
All patients underwent successful LMA or ETT placement within 2 attempts. There was no difference in highest mean (SD) peak airway pressure during carboperitoneum between the LMA and ETT groups (17.7 [2.8] mm Hg vs 19.1 [3.8] mm Hg, P = .159, respectively). The incidence of high systolic blood pressure and bradycardia was higher in the LMA group. The highest pain scores 1 hour postoperatively and on postoperative day 1 were lower in the LMA group than in the ETT group (3.9 [2.0] vs 5.4 [2.3], P = .017 and 5.6 [1.9] vs 6.7 [1.7], P = .042, respectively); requirements for analgesics were similar in the 2 groups. The incidence of nausea was lower in the LMA group than in the ETT group until postoperative day 1 (4/28 [14%] vs 12/28 [43%], P = .031, respectively).

Conclusion:
The LMA Protector was an effective ventilator device associated with fewer intraoperative hemodynamic stress responses and improved the quality of early recovery after laparoscopic cholecystectomy.
Clinical application of RNA sequencing in sarcoma diagnosis
Authors: Pei Jianming , Zhao Xiaofeng , Patchefsky Arthur S. , Flieder Douglas B. , Talarchek Jacqueline N. , Testa Joseph R. , Wei Shuanzeng 
Published: June 2019

Abstract
Accurate diagnoses of sarcoma are sometimes challenging on conventional histomorphology and immunophenotype. Many specific genetic aberrations including chromosomal translocations have been identified in various sarcomas, which can be detected by fluorescence in situ hybridization and polymerase chain reaction analysis. Next-generation sequencing-based RNA sequencing can screen multiple sarcoma-specific chromosome translocations/fusion genes in 1 test, which is especially useful for sarcoma without obvious differentiation. In this report, we utilized RNA sequencing on formalin-fixed paraffin-embedded (FFPE) specimens to investigate the possibility of diagnosing sarcomas by identifying disease-specific fusion genes. Targeted RNA sequencing was performed on 6 sarcoma cases. The expected genetic alterations (clear cell sarcoma/EWSR1-ATF1, Ewing sarcoma/EWSR1-FLI1, myxoid liposarcoma/DDIT3-FUS) in four cases were detected and confirmed by secondary tests. Interestingly, three SS18 fusion genes (SS18-SSX2B, SS18-SSX2, and SS18-SSX4) were identified in a synovial sarcoma case. A rare fusion gene (EWSR1-PATZ1) was identified in a morphologically challenging case; which enabled us to establish the diagnosis of low grade glioneural tumor. In conclusion, RNA sequencing on FFPE specimen is a reliable method in establishing the diagnosis of sarcoma in daily practice.
Pathological complete response from oral chemotherapy combined with trans-arterial chemotherapy and embolization in an unresectable gastric cancer patient
Authors: Su Zhaoran , Shu Kuanshan , Kang Min , Wang Guihe 
Published: June 2019

Abstract

Rationale:
Gastric cancer is still one of the most common cancer in East Asia. More than 70% gastric cancer patients are diagnosed at an advanced stage in China. Moreover, about 10% cases are unresectable which usually suffer a poor prognosis with a median survival time of 5 to 12 months. In recent years, some clinical studies found that many unresectable gastric cancer cases could get opportunity for surgery after treatment that improve prognosis significantly

Patient concerns:
64-year-old male patient was admitted with upper abdominal pain. Upper gastrointestinal endoscopy showed a large ulcerated tumor located from the cardia to the anterior wall of the upper gastric body. Histopathological examination showed it was moderately differentiated adenocarcinoma. Computed tomography (CT) scan image showed a large bulging mass with internal ulcer at the lesser curvature wall, left gastric artery and coeliac trunk were surrounded by fused lymph nodes.

Diagnoses:
Based on the histopathological examination and imaging findings, patient was diagnosed advanced gastric cancer and hardly to resect radically.

Intervention:
Oral chemotherapy combined with trans-arterial chemotherapy and embolization (TACE) was initiated. Eight weeks after initial therapy, radical laparoscopy-assisted total gastrectomy with D2 lymph node dissection and Roux-en-Y anastomosis were performed successfully.

Outcomes:
Patient was discharged on postoperative day 11 without complications. Histological analysis of the specimen and resected 31 lymph nodes revealed no malignancy. The patient experienced a pathological complete response (pCR).

Lessons:
In this case, oral chemotherapy combined with TACE which was rarely reported in the treatment of unresectable gastric cancer achieves a great therapeutic benefit. Although further clinical studies will be needed to establish, it may be a potent strategy for degrading stage and supplying a new chance for surgery.
Ologen implant versus mitomycin-C for trabeculectomy
Authors: Song De-Sheng , Qian Jing , Chen Zhi-Jun 
Published: June 2019

Abstract

Aim:
To evaluate the efficacy and safety of trabeculectomy (Trab) with mitomycin-C (MMC) versus Trab with implant.

Methods:
Studies published in different languages were retrieved by systematically searching Embase, PubMed, Cochrane library, China Biology Medicine disc, and Google Scholar from 1966 to April 2018, as well as manually examining the references of the original articles. The outcome measures of efficacy covered intraocular pressure, glaucoma medications reductions, and success rate. Safety evaluation was measured by relative ratio of complications.

Results:
A total of 11 studies involving 443 participants were covered in this meta-analysis. The weighted mean difference (WMD) in the percentage of intraocular pressure (IOP) reduction (IOPR%) comparing Ologen group with MMC group was −3.69 (95% CI: −6.70 to −0.68) at 1 month, −2.69 (−5.17 to −0.21) at 3 months, −3.67 (−6.09 to −1.25)at 6 months, −3.24 (−6.08 to −0.41) at 12 months, 1.24 (−9.43 to 11.90) at 24 months, and 1.10 (−10.11 to 12.31) at 60 months, which showed that there was statistically significant difference at 1,3, 6, and12 months after the surgery. A significantly higher incidence of postsurgery hypotony (0.64 (95% Cl: 0.42 to 0.98)) and suture lysis (0.30 (95% CI: 0.10–0.93)) was observed in MMC group. However, there was no significant difference in the reduction in glaucoma medications, success rate, and incidence of other complications.
Trab with 0.2 mg/mL MMC presented higher rates of complete success compared with Trab with 0.4 mg/mL MMC (P = .01).

Conclusion:
Trab with MMC was associated with a higher IOP-lowering efficacy and a higher incidence of postsurgery hypotony and suture lysis in contrast to that of Trab with Ologen.