bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcomes and complications following non-oncologic total femoral replacement
Authors: Christ Alexander B , Mendez Logan , Gausden Elizabeth B , Blevins Jason L , Bostrom Mathias P , Sculco Peter K 
Published: July 2019

Background: Non-oncologic total femoral replacement (TFR) is utilised as a limb-salvage option in the setting of massive bone loss during revision total hip arthroplasty (THA) and total knee arthroplasty (TKA). However, complication rates, including infection and reoperation, remain a concern. Methods: In this study, 16 consecutive TFRs from a single institution with an average clinical follow-up of 4 years were retrospectively reviewed. Indications for TFR, previous surgeries, implants used, complications, reoperations, and ambulatory status at final follow-up were recorded. Results: The reoperation rate was 50%, and those patients averaged 2 additional surgeries after TFR. The most common reason for reoperation was infection with a 33% incidence of a new periprosthetic infection and an overall infection rate of 44% (7/16). 6/7 were managed with irrigation and debridement and implant retention. Dual-mobility and constrained acetabular liners were used consistently, and no patient experienced a subsequent dislocation. At final follow-up, 81% were ambulatory but only 2 patients (13%) could walk without an assistive device. No patient required amputation. Conclusions: While TFR achieved limb salvage in all patients with fair clinical outcomes, patients were at high risk for new or persistent infection and reoperation. Dual-mobility and constrained acetabular liners were effective in preventing dislocation is this cohort.
Noninvasive Neuromonitoring of Hypothermic Circulatory Arrest in Aortic Surgery
Authors: Stewart J. A. , Särkelä M. O. K. , Salmi T. , Wennervirta J. , Vakkuri A. P. , Vainikka T. L. S. , Suojaranta R. , Mäki K. , Ilkka V. H. , Viertiö-Oja H. , Salminen U.-S. 
Published: July 2019

Background and Aims: Circulatory arrest carries a high risk of neurological damage, but modern monitoring methods lack reliability, and is susceptible to the generalized effects of both anesthesia and hypothermia. The objective of this prospective, explorative study was to research promising, reliable, and noninvasive methods of neuromonitoring, capable of predicting neurological outcome after hypothermic circulatory arrest. Materials and Methods: Thirty patients undergoing hypothermic circulatory arrest during surgery of the thoracic aorta were recruited in a single center and over the course of 4 years. Neuromonitoring was performed with a four-channel electroencephalogram montage and a near-infrared spectroscopy monitor. All data were tested off-line against primary neurological outcome, which was poor if the patient suffered a significant neurological complication (stroke, operative death). Results: A poor primary neurological outcome seen in 10 (33%) patients. A majority (63%) of the cases were emergency surgery, and thus, no neurological baseline evaluation was possible. The frontal hemispheric asymmetry of electroencephalogram, as measured by the brain symmetry index, predicted primary neurological outcome with a sensitivity of 79 (interquartile range; 62%–88%) and specificity of 71 (interquartile range; 61%–84%) during the first 6 h after end of circulatory arrest. Conclusion: The hemispheric asymmetry of frontal electroencephalogram is inherently resistant to generalized dampening effects and is predictive of primary neurological outcome. The brain symmetry index provides an easy-to-use, noninvasive neuromonitoring method for surgery of the thoracic aorta and postoperative intensive care.
Biosignals to Detect the Imbalance of Explicit and Implicit Affect in Dementia: A Pilot Study
Authors: Han Doug Hyun , Ga Hyuk , Kim Sun Mi , Kim Soyoung , Chang Joon Seok , Jang Sunghyuk , Lee Sang Hoon 
Published: July 2019

Background: We assessed implicit and explicit emotion in older patients with dementia using biosignals. Methods: Fifty patients with dementia and 34 healthy individuals watched 3 videos that aimed to elicit various emotional responses. Electroencephalogram and heart rate variability were recorded. Results: Patients with dementia experienced less fun and more fear than controls. The high frequency (HF) from the baseline in response to funny stimulation as well as HF from neutral to fear stimulation in the dementia group increased further than in the control group. The slow wave (SW)–fast wave (FW) ratio from neutral to funny stimulation in the control group increased further than in the dementia group. The SW-FW from neutral to fear stimulation was further decreased in the dementia group than in the control group. Conclusions: Although patients with dementia were more sensitive to implicit affect, they showed more enhanced imbalance between positive and negative affect in explicit affect assessment.
Pectoralis Major Rupture in Military Academy Athletes
Authors: Chan Andrew G. , Balazs George C. , Haley Chad A. , Posner Matthew A. , Rue John-Paul H. , Owens Brett D. 
Published: July 2019

Background: Pectoralis major ruptures are rare injuries that can occur at several parts of the muscle. Little is known of the pathoanatomic process and performance following pectoralis major ruptures in young athletes. Purpose/Hypothesis: The objective of this study was to describe a series of pectoralis major ruptures in military academy athletes at the US Military Academy and US Naval Academy. We hypothesized that military academy athletes will demonstrate a different rupture location than previously reported in older patients. Study Design: Case series; Level of evidence, 4. Methods: A retrospective case series was performed by analyzing all electronic medical records and imaging software for consecutive pectoralis major ruptures undergoing surgical repair within the student population at 2 military academies. The primary outcome of interest was rupture pattern and location. We also assessed functional recovery following surgery by analyzing push-up performance on the biannual Army Physical Fitness Test and Navy Physical Readiness Test. Results: From 2005 to 2017, a total of 19 cases of pectoralis major ruptures occurred in military academy cadets. Patients ranged in age from 19 to 23 years, with a mean age of 20 years. All injuries occurred during sports activity, with bench press as the most common mechanism of injury (n = 10; 53%). The most common rupture location was the musculotendinous junction (n = 10; 53%), followed by pectoralis major tendon insertion (n = 8; 42%), and only 1 bony avulsion was noted. Physical activity performance following the rupture was negatively affected. The mean ± SD number of push-ups preinjury was 73.20 ± 12.10, which decreased following injury and surgery (66.50 ± 11.98; P = .037). Conclusion: Military academy athletes in our study cohort demonstrated a different type of rupture location than has been reported in older cohorts, with the majority experiencing tearing at a location other than the tendon itself. Performance was also negatively affected immediately following repair, but moderate improvement was observed as time from surgery increased.
Refractory depression – mechanisms and efficacy of radically open dialectical behaviour therapy (RefraMED): findings of a randomised trial on benefits and harms
Authors: Lynch Thomas R. , Hempel Roelie J. , Whalley Ben , Byford Sarah , Chamba Rampaul , Clarke Paul , Clarke Susan , Kingdon David G. , O'Mahen Heather , Remington Bob , Rushbrook Sophie C. , Shearer James , Stanton Maggie , Swales Michaela , Watkins Alan , Russell Ian T. 
Published: July 2019

BackgroundIndividuals with depression often do not respond to medication or psychotherapy. Radically open dialectical behaviour therapy (RO DBT) is a new treatment targeting overcontrolled personality, common in refractory depression.AimsTo compare RO DBT plus treatment as usual (TAU) for refractory depression with TAU alone (trial registration: ISRCTN 85784627).MethodRO DBT comprised 29 therapy sessions and 27 skills classes over 6 months. Our completed randomised trial evaluated RO DBT for refractory depression over 18 months in three British secondary care centres. Of 250 adult participants, we randomised 162 (65%) to RO DBT. The primary outcome was the Hamilton Rating Scale for Depression (HRSD), assessed masked and analysed by treatment allocated.ResultsAfter 7 months, immediately following therapy, RO DBT had significantly reduced depressive symptoms by 5.40 points on the HRSD relative to TAU (95% CI 0.94–9.85). After 12 months (primary end-point), the difference of 2.15 points on the HRSD in favour of RO DBT was not significant (95% CI –2.28 to 6.59); nor was that of 1.69 points on the HRSD at 18 months (95% CI –2.84 to 6.22). Throughout RO DBT participants reported significantly better psychological flexibility and emotional coping than controls. However, they reported eight possible serious adverse reactions compared with none in the control group.ConclusionsThe RO DBT group reported significantly lower HRSD scores than the control group after 7 months, but not thereafter. The imbalance in serious adverse reactions was probably because of the controls' limited opportunities to report these.
CsTFL1 inhibits determinate growth and terminal flower formation through interaction with CsNOT2a in cucumber
Authors: Wen Changlong , Zhao Wensheng , Liu Weilun , Yang Luming , Wang Yuhui , Liu Xingwang , Xu Yong , Ren Huazhong , Guo Yangdong , Li Cong , Li Jigang , Weng Yiqun , Zhang Xiaolan 
Published: July 2019

ABSTRACT
Cucumber (Cucumis sativus L.) is an important vegetable crop that carries on vegetative growth and reproductive growth simultaneously. Indeterminate growth is favourable for fresh market under protected environments, whereas determinate growth is preferred for pickling cucumber in the once-over mechanical harvest system. The genetic basis of determinacy is largely unknown in cucumber. In this study, map-based cloning of the de locus showed that the determinate growth habit is caused by a non-synonymous SNP in CsTFL1. CsTFL1 is expressed in the subapical regions of the shoot apical meristem, lateral meristem and young stems. Ectopic expression of CsTFL1 rescued the terminal flower phenotype in the Arabidopsis tfl1-11 mutant and delayed flowering in wild-type Arabidopsis. Knockdown of CsTFL1 resulted in determinate growth and formation of terminal flowers in cucumber. Biochemical analyses indicated that CsTFL1 interacts with a homolog of the miRNA biogenesis gene CsNOT2a; CsNOT2a interacts with FDP. Cucumber CsFT directly interacts with CsNOT2a and CsFD, and CsFD interacts with two 14-3-3 proteins. These data suggest that CsTFL1 competes with CsFT for interaction with CsNOT2a-CsFDP to inhibit determinate growth and terminal flower formation in cucumber.
Quantification of Agility Testing with Inertial Sensors after a Knee Injury
Authors: KIM KYOUNG JAE , GAILEY ROBERT , AGRAWAL VIBHOR , GAUNAURD IGNACIO , FEIGENBAUM LUIS , BENNETT CHRISTOPHER , FELT VIOLET , BEST THOMAS M. 
Published: July 2019

ABSTRACT

Introduction
A common criterion in decision making regarding return to sport (RTS) after knee ligament injury is that athletes should achieve symmetrical bilateral movement between the injured limb and the noninjured limb. Body-worn wireless inertial measurement units (IMU) can provide clinicians with valuable information about lower-limb kinematics and athletic performance.

Methods
The IMU-based novel kinematic metrics were developed. The Transitional Angular Displacement of Segment (TADS) and Symmetry Index (SI) measures that quantify lower-limb motions and interlimb symmetry during the 4-m side step test (FmSST) were developed. Test–retest reliability was measured in 20 healthy adults. Experimental application of the metrics was also determined in 15 National Collegiate Athletic Association Division I collegiate athletes who completed rehabilitation after a knee ligament injury.

Results
The intraclass correlation coefficient for test–retest reliability for FmSST, TADS right lower limb, TADS left lower limb, and TADS SI was 0.90 (95% confidence interval, [0.61–0.95]); 0.87 [0.63–0.96]; 0.89 [0.64–0.96], and 0.81 [0.58–0.92], respectively. The differences between TADS SI at baseline (preinjury) and RTS were also compared with those between the total times for performing the FmSST at baseline and RTS. There was no significant difference in the FmSST times between baseline and RTS (P = 0.32); however, TADS SI at the time of RTS was significantly lower than at baseline (P = 0.046). A large effect size (d = −1.04) was observed for the change in TADS SI from baseline to RTS.

Conclusions
Using IMU sensor technology can provide quantitative and discrete analysis to detect kinematic differences during agility after a knee ligament injury in the field or nonlaboratory setting. This approach has the potential to help clinicians improve decisions about rehabilitation at a time when an athlete is reintegrating back into sport.
Use of artificial neural network for pretreatment verification of intensity modulation radiation therapy fields
Authors: Mahdavi Seied Rabie , Tavakol Asieh , Sanei Mastaneh , Molana Seyed Hadi , Arbabi Farshid , Rostami Aram , Barimani Sohrab 
Published: July 2019

Objective:
The accuracy of dose delivery for intensity modulated radiotherapy (IMRT) treatments should be determined by an accurate quality assurance procedure. In this work, we used artificial neural networks (ANNs) as an application for the pre-treatment dose verification of IMRT fields based two-dimensional-fluence maps acquired by an electronic portal imaging device (EPID).

Methods:
The ANN must be trained and validated before use for the pretreatment dose verification. Hence, 60 EPID fluence maps of the anteroposterior prostate and nasopharynx IMRT fields were used as an input for the ANN (feed forward type), and a dose map of those fluence maps that were acquired by two-dimensional Array Seven29TM as an output for the ANN.

Results:
After the training and validation of the neural network, the analysis of 20 IMRT anteroposterior fields showed excellent agreement between the ANN output and the dose map predicted by the treatment planning system. The average overall global and local γ field pass rate was greater than 90% for the prostate and nasopharynx fields, with the 2 mm/3% criteria.

Conclusion:
The results indicated that the ANN can be used as a fast and powerful tool for pretreatment dose verification, based on an EPID fluence map.

Advances in knowledge:
In this study, ANN is proposed for EPID based dose validation of IMRT fields. The proposed method has good accuracy and high speed in response to problems. Neural network show to be low price and precise method for IMRT fields verification
Expertise and Discretionary Bonus Decisions
Authors: Abernethy Margaret A. , Hung Chung-Yu , van Lent Laurence 
Published: July 2019

We examine the association between managers’ expertise and their discretionary bonus decisions in a hospital setting. We hypothesize that high-expertise managers make decisions that encourage cooperation among their subordinates. However, low-expertise managers cannot do so because their lower levels of knowledge, experience, and domain expertise prevent them from having sufficient personal influence to persuade other professionals to cooperate. We find that high-expertise managers make two types of bonus decisions: (1) keep a smaller share of the bonus pool than what they are entitled to retain and (2) allocate the remainder to subordinates more evenly after adjusting for the underlying heterogeneity in their productivity. We also find evidence that high-expertise managers whose bonus decisions reflect their support for cooperation have higher department performance than all other managers. This paper was accepted by Suraj Srinivasan, accounting.
Reflections on the Domestic Violence Disclosure Scheme (England and Wales)
Authors: Duggan Marian 
Published: July 2019

The Domestic Violence Disclosure Scheme (DVDS) aims to reduce harm through improving access to background information for people with concerns about a romantic partner’s behaviour. This reduction is predicated on the disclosure recipient taking steps to ensure their safety, either by managing the situation or ending the relationship. As fewer than half of the thousands of annual applications result in disclosures, and no information is held about any subsequent steps taken by applicants or recipients, it is unclear whether or not the DVDS is actually reducing domestic violence. Nonetheless, Scotland and Northern Ireland have implemented their own variations of this policy, as have some Canadian and Australian states.
This policy analysis draws on empirical research into the DVDS in terms of its national and local operation in order to assess the strengths and limitations of its capacity to reduce harm. The analysis outlines how the policy may be difficult to access; deflect – rather than prevent – harm; shift safeguarding responsibilities onto the most vulnerable; and be incorrectly interpreted in terms of outcome. The paper makes recommendations for improvement in order to enhance the policy’s efficacy.
Afferent Loop Syndrome Due to Volvulus of the Afferent Limb
Authors: Desai Aditi , Manvar Amar , Ho Sammy 
Published: July 2019

ABSTRACT
A 78-year-old woman with a history of stage IIB gastric adenocarcinoma with previous Billroth II subtotal gastrectomy was admitted with pancreatitis, with subsequent development of fevers and acute jaundice. Transabdominal ultrasound demonstrated bile duct obstruction. An endoscopic retrograde cholangiopancreatography was attempted, but the lumen of the afferent limb appeared distorted without an obstructing lesion. A computed tomography scan demonstrated volvulus of the afferent limb near the gastrojejunal anastomosis, with afferent limb dilation and significant biliary dilation.
Pendidikan Karakter dalam Kaulinan Budak Baheula: Studi Nilai Pendidikan Karakter Melalui Permainan Anak Tradisional Sorodot Gaplok Dari Jawa Barat
Authors: Amirudin Amirudin , Mukarom Zaenal 
Published: July 2019

Sorodot Gaplok merupakan salah satu jenis permainan anak tradsional (kulianan budak baheula) khas Jawa Barat. Secara eksistensial, Sorodot Gaplok dapat dikategorikan sebagai permainan popular khususnya bagi warga masyarakat Desa Manggung Jaya, Kecamatan Cilamaya Kulon, Kabupaten Karawang. Hal ini dikarenakan permainan tradisional ini bukan hanya dilakukan oleh anak-anak, tapi juga oleh orang dewasa. Dilihat dari bentuk dan karakter permainannya, Sorodot Gaplok dipandang bukan saja sebagai permainan mengisi waktu luang, melainkan sarat akan nilai-nilai moral dan pendidikan karakter di dalamnya. Atas dasar itu, studi ini bertujuan untuk mengungkap nilai-nilai moral dan pendidikan karakter dalam permainan sorodot gaplok di kalangan warga masyarakat Desa Manggung Jaya, Kecamatan Cilamaya Kulon, Kabupaten Karawang. Studi ini menggunakan metode studi kasus dengan landasarn teori dari Rogers & Sawyers tentang nilai-nilai dalam aktifitas bermain anak. Hasil studi menunjukkan bahwa: 1) Permainan sorodot gaplok bersifat rekreatif, kompetitif, dan edukatif; 2) Permainan sorodot gaplok termasuk ke dalam model pembelajaran outdoor education; 3) Permainan sorodot gaplop dapat menstimuli enam aspek yaitu motorik, kognitif, emosi, sosial, ekologi, dan moral; 4)Permianan sorodot gaplok memiliki empat dimensi pendidikan karakter yaitu problem solving, kekuatan verbal dan nonverbal, keterampilan sosial, serta ekspresi emosi. Dengan beberapa temuan tersebut, studi ini diharapkan dapat memperkaya dan melengkapi kajian tentang pentingnya pelestarian nilai-nilai budaya local sebagai salah satu model penguatan pembentukan dan pendidikan karakter anak bangsa. Disamping itu, studi ini diharapkan dapat menjadi mainstreaming akan pentingnya pembangunan berwawasan pendidikan yang ramah anak terutama bagi para pemegang kebijakan.
Seraja Szapszał – hachan karaimski w Drugiej Rzeczypospolitej w świetle dokumentów Ministerstwa Wyznań Religijnych i Oświecenia Publicznego
Authors: Resler Tomasz 
Published: July 2019

Artykuł ukazuje hachana jako przywódcę religijnego w oczach władz państwowych przez pryzmat dokumentów zgromadzonych w Ministerstwo Wyznań Religijnych i Oświecenia Publicznego. Instytucja ta miała decydujący wpływ na prowadzenie polityki wyznaniowej przez przekuwanie koncepcji i idei politycznych w praktyczne działania państwa. Ukazanie, w jaki sposób hachan karaimski był postrzegany przez urzędników MWRiOP uzupełni lukę w badaniach nad historią i pozycją prawną tej społeczności. Literatura przedmiotu do tej pory nie pochyliła się wystarczająco nad tym, jak Seraja Szapszał był odbierany przez władze państwowe. Ukazanie tego wątku pomaga lepiej zrozumieć politykę państwa wobec Karaimów, a także przyczynia się do ukazania genezy ustawy regulującej wzajemne relacje oraz dopełnia obraz społeczności karaimskiej przed II wojną światową. Artykuł odpowiada na pytania o stosunek państwa do Karaimów jako społeczności, stosunek władz do Seraji Szapszała oraz ich wzajemne relacje, wskazując obszary, które mogły wywoływać animozje.
Language learning and inclusion in Italy
Authors: Carloni Giovanna , Sisti Flora 
Published: July 2019

Abstract
The study of inclusion models has regained attention in light of recent migratory phenomena. In this context, research in the area of second language (L2) teaching methodologies occupies a central role because it examines the most effective teaching approaches to promote the learning of a language that will be instrumental in the inclusion of the migrant
For a definition of migrant see the European Migration Network (EMN) Glossary: “In the global context, a person who is outside the territory of the State of which they are nationals or citizens and who has resided in a foreign country for more than one year irrespective of the causes, voluntary or involuntary, and the means, regular or irregular, used to migrate”. https://ec.europa.eu/home-affairs/what-we-do/networks/european_migration_network/glossary_en (accessed April 7, 2018). in a new socio-cultural context. This work proposes some reflections on the bonds between language and cultural identity, with particular focus on the problematics related to culture shock. The premise is that language plays a key role as an instrument in inclusion because it allows the individual to understand a new reality and to make him or herself understood by others through a narrative process (storytelling). To promote the true inclusion of migrants into the fabric of the society of the adopted country, it is important to pursue a dual objective: to provide migrants with the instruments necessary for inclusion into the host society and, at the same time, educate the members of the host society as regards intercultural relationships. The purpose of this work is to furnish some research-based guidelines suitable to effective L2 teaching and present an example of an experience in the process of inclusion mediated through Italy’s works of art in museums.
“Cultura e accoglienza”: The inclusion of asylum seeker students in university language courses. Initial experience and data
Authors: Duso Elena Maria , Marigo Luisa 
Published: July 2019

AbstractIn 2016 the University of Padova and its Language Centre (Centro Linguistico di Ateneo– CLA) became involved in the two-year “Cultura e accoglienza” Project (see Dalziel and Piazzoli in this volume), the aim of which was to encourage around 30 refugees and asylum seekers to pursue university studies by means of a personalized training programme with support from language teachers and tutors. This report first describes some of the main national projects regarding the inclusion of refugee/asylum seekers in Italy and then describes the “Cultura e accoglienza” project, highlighting some of the opportunities and challenges it presented. For the Language Centre this was the very first experience of this kind.