bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermodynamic properties of fluorapophyllite-(k) and hydroxylapophyllite-(k)
Authors: Ogorodova L. P. , Melchakova L. V. , Vigasina M. F. , Grytsenko Yu. D. , Ksenofontov D. A. , Bryzgalov I. A. 
Published: July 2019

Thermochemical study of natural minerals of the apophyllite group: fluorapophyllite-(K) KCa4[Si8O20]F . 8H2O (Maharashtra, India) (I) and hydroxylapophyllite-(K) KCa4[Si8O20]OH . 8H2O (Norilsk, Russia) (II) were performed on a high-temperature heat-flux microcalorimeter Tian–Calvet “Setaram” (France) using the melt solution calorimetry method. The first data on the enthalpies of formation from the elements for the minerals studied are obtained: -13 205±13 kJ/mol (I) and -13 054±20 kJ/mol (II). The values of their standard entropies and Gibbs energies of formation are estimated.
Acute effect of successive matches in salivary cortisol concentrations and match internal load in young soccer players
Authors: de Lima Pinto Julio Cesar Barbosa , Fortes Leonardo Sousa , Lemos Telma Maria Araujo Moura , Mortatti Arnaldo Luis 
Published: July 2019

BACKGROUND: Sports competitions are significant sources of psychophysiological stress, especially for young athletes submitted to competitions in a congested match schedule. OBJECTIVE: In order to verify the effect of short recovery periods (24-hours) in the subsequent match, the response of salivary cortisol (sC) and match intensity were investigated in two successive soccer matches during an official tournament. METHODS: Twenty (20) young soccer players (16.8 [Formula: see text] 0.5 years; 172.9 [Formula: see text] 7.7 cm; 65.0 [Formula: see text] 7.9 kg) accepted to participate and 14 completed the 2 matches within a two day-period. Subjects provided saliva samples before and after each match and the session rate of perceived exertion, (session-RPE) method was utilized to define the match intensity. RESULTS: The sC concentration significantly increased in both matches ([Formula: see text] 0.05), representing an increase of 74% and 112% in matches 1 and 2, respectively. Moreover, the variation was not different between the matches ([Formula: see text] 0.05). There was no variation in match internal load for match 1 to match 2 ([Formula: see text] 0.05). A significant difference was noted between high and low salivary cortisol groups divided a posteriori into both matches (match 1: [Formula: see text] 0.001; ES: 2.7 and match 2: [Formula: see text] 0.001; ES: 2.3). CONCLUSIONS: The findings of this study indicate that the short recovery-time did not influence the sC and match internal load responses in the subsequent match. In addition, athletes with high responsiveness to the stressful demands of the matches tend to maintain this condition regardless of the time on field and the RPE reported.
Isokinetic evaluation of the wrist flexors and extensors in women with postmenopausal osteoporosis
Authors: Şenlikci Hüma Bölük , Ersöz Murat , Gülçin Ural Fatma , Öztürk Gökhan Tuna 
Published: July 2019

BACKGROUND: Distal radius fractures are the third most common fracture observed in osteoporotic patients. In addition, wrist muscle weakness may be a risk factor for such fractures because of the protective role these muscles play during falls. OBJECTIVE: The main objective was to explore isokinetic wrist muscle strength in osteoporotic and matched non-osteoporotic postmenopausal women. MATERIALS AND METHODS: Twenty osteoporotic postmenopausal women (patient group) and 15 healthy non-osteoporotic postmenopausal women with a normal DXA score (control group) were recruited. Bone mineral density was measured using a DXA device. Vertebral (L1–L4), femoral neck, and femoral total measurements were recorded. Wrist muscle strength was evaluated isokinetically. RESULTS: Peak moment values of the wrist flexors at 60 and 180[Formula: see text]/s were significantly lower in the patient group than in the control group. Extensor muscle strength did not differ significantly between the 2 groups. CONCLUSION: Wrist flexors strength is lower in osteoporotic postmenopausal women than their non-osteoporotic counterparts. As this variation might be a risk factor for distal radius fractures in osteoporotic postmenopausal women, strengthening this muscle group should be seriously explored.
EXPERIMENTAL INVESTIGATION ON CARBACETAM INFLUENCE ON HYPOTHALAMUS TISSUE IN BRAIN INJURY
Authors: Ziablytsev S.V. , Panova T.I. , Starodubska O.O. , Dyadik O.O. 
Published: July 2019

Relevance. A key role in the pathogenesis of the brain injury is played by destructive changes in the hypothalamus neuroendocrine cells. For the correction of such disorders, promising is carbacetam, which has antihypoxic, anti-edema and anti-shock effects. Objective: to investigate the effect of carbacetam on the processes of neurodegeneration in the paraventricular and supraoptical nuclei of the hypothalamus in the experimental brain injury. Material and methods. Brain injury were modeled on the V.M. Elskyy &S.V. Ziablitsev model on white non-breeding male rats weighing 200±10 g. Experimental animals (n=10) received intraabdominal injection of carbacetam at a dose of 5 mg/kg in 1 ml of physiological saline during the seven days after injury. In the control group (n=10), 1 ml of physiological saline was injected. Hypothalamic tissue microparticles performed a morphological and immunohistochemical evaluation of neurodegenerative changes when stained with hematoxylin and eosin and immunohistochemically to detect NSE, S-100 and GFAP neuromarkers. Results. Carbacetam reduced the degenerative processes in the nervous tissue of the paraventricular and supraoptical nuclei of the hypothalamus, which was manifested by the restoration of normal morphological features, in contrast to rats that did not receive the drug. Immunohistochemically, GFAP and S-100 glial markers exhibited reduced, reflecting a reduction in degenerative changes in the nerve tissue. Expressions of the neurons marker NSE increased, reflecting high metabolic activity of the neurons. Conclusions. Revealed changes in the expression of markers of neurons and glia showed a restoration of normal neuronal activity due to the introduction of carbacetam.
MEGALOBLASTIC PANCYTOPENIA MIMICKING HELLP SYNDROME IN LATE PREGNANCY: A CASE REPORT
Authors: Sharma Siddharth , Das Kunal , Kala Mansi , Shukla Sushil Kumar , Nautiyal Ruchira , Kusum Anuradha 
Published: July 2019

Introduction: Hemolysis, Elevated liver enzyme, low platelet (HELLP) syndrome is often noted as a complication of preeclampsia but can occur without this association as well. Severe form often requires termination of pregnancy. Vitamin B12 deficiency is common in vegetarian population and can mimic HELLP syndrome.
Case Summary: We present an interesting case which was initially thought to be HELLP syndrome based on the clinical presentation and patient was planned for induction of labour, but later on it was found out to be a case of Vitamin B12 deficiency on the basis of Lab findings. Patient responded well to the B12 supplementation and unjustified termination of pregnancy was avoided.
Conclusion: This case illustrates an interesting clinical misdiagnosis of HELLP syndrome in an overt megaloblastic anemia. An elaborated workup with clinical suspicion should be made for megaloblastic anemia in such condition.
Keywords: HELLP syndrome, Megaloblastic Anemia, Vitamin B12 deficiency, Pregnancy
STUDY OF THE SERUM LEVELS OF VITAMIN D AND CALCIUM IONIZED IN THYROID DISORDERS
Authors: Amer Abdulrahman Hefdhallah , Chaudhari Kaushik , Trivedi Riyaben , Patel Riddhi 
Published: July 2019

Background
Vitamin D deficiency is a global health problem, and its role as an immune modulator has been recently tightened. The main role of vitamin D is to maintain calcium and phosphorus homeostasis, thus maintaining bone health. Recent evidence has shown that vitamin D may play a role in a variety disorders such as endocrine diseases, adrenal diseases, polycystic ovary syndrome and particular type 1 diabetes, type 2 diabetes. We evaluated the association between thyroid disorders (subclinical or overt hypothyroidism and subclinical or overt hyperthyroidism) and serum vitamin D3 level in the Indian population and its association with ionized calcium.
Methods
The cross-sectional study, included patients who visited Shree Krishna Hospital, Karamsad for thyroid evaluation or follow-up. We conducted this study involving a total of 84 individuals with normal thyroid function, were recorded as control. The cases group included 75 patients with hypothyroidism (overt or subclinical) and 10 patients with hyperthyroidism (overt or subclinical). Serum levels of vitamin D3, thyroid function and calcium ionized were measured in all adult subjects. Deficiency of vitamin D is defined as the level of vitamin D3 in the serum less than 50 nmol/L. Vitamin D insufficiency is defined as serum vitamin D3 level between 50 - 75 nmol/L. Vitamin D sufficiency is defined as serum Vit D3 level >75 nmol/L.
Result
The prevalence of vitamin D deficiency in subclinical and clinical hypothyroidism cases (36 of 40, 90%) was significantly higher than that observed in healthy individuals (0 of 40, 0%). The prevalence of vitamin D deficiency in subclinical and clinical hyperthyroidism cases (4 of 40, 10%). The prevalence of vitamin D insufficiency in subclinical and clinical hypothyroidism cases (24 of 62, 38.7%) was significantly lower than that observed in healthy individuals (controls) (35 of 62, 56.5%).The prevalence of vitamin D insufficiency in subclinical and clinical hyperthyroidism cases (3 of 62, 4.8%). The prevalence of vitamin D sufficiency in subclinical and clinical hypothyroidism cases (15 of 67, 22.4%) was significantly lower than that observed in healthy individuals (controls) (49 of 67, 73.1 %). The prevalence of vitamin D sufficiency in subclinical and clinical hyperthyroidism cases (3 of 67, 4.5%).
Conclusion
Vitamin D deficiency was associated with hypothyroidism especially clinical hypothyroidism. Low serum levels of vitamin D3 were associated with high serum TSH levels.
Keyword: Vitamin D3, calcium ionized, hypothyroidism and hyperthyroidism.
A STUDY TO ASSESS THE BIOCHEMICAL PROFILE IN HEALTHY YOUNG MEDICAL PROFESSIONALS IN INDIA
Authors: Raj Bishnu , Kumar Ashwini , Misra Pratibha , Bhatia Kapil , Mukherjee Bhasker , Ambade Vivek N 
Published: July 2019

Introduction: Cardiovascular diseases are the most prevalent cause of mortality and morbidity in both developed as well as developing countries. Coronary artery disease (CAD) is usually due to atherosclerosis of large and medium sized arteries. Dyslipidemia and hyperglycemia have been found to be the important contributing factors.
Aims and objectives: Present study is done to know the pattern of dyslipidemia and blood glucose status as per National Cholesterol Education Program – Adult treatment panel III (NCEP-ATP III) guidelines and American Diabetes Association (ADA) criteria respectively in young doctors and to sensitize the importance of its implication and to take timely preventive measures.
Material and methods: This is a retrospective observational study conducted in a tertiary care hospital. The study group comprised of 173 young doctors from all over India, between age 25 to 29 years who reported to lab for routine medical investigations. The study group included 118 males and 55 females. Serum lipid profile and plasma glucose for 173 subjects were analyzed.
Results: In our study 71.7% of total study group had impaired range of plasma glucose values and 10.4% had diabetic range plasma glucose.5.78% of total subjects had Triglyceride (TG) level more than 200 mg/dL.11.56% had total cholesterol (TC) level >240 mg/dL. 45.66% of total subjects had Low density lipoprotein cholesterol (LDLc) more than 130 mg/dL. 37.2% of males had high density lipoprotein cholesterol (HDLc) less than 40 mg/dL. 40% of females had HDLc less than 50 mg/dL. Thereby implying that even apparently healthy young medical professionals are at increased risk of metabolic disorders like diabetes and dyslipidemia.
Conclusion: This study revealed higher prevalence of hyperglycemia and dyslipidemia in apparently healthy medical professionals suggesting higher risk for metabolic disorders like coronary artery disease and diabetes mellitus. The study indicates the need for physical exercise, change in dietary pattern and regular monitoring of biochemical indicators of metabolic diseases.
Keywords: Dyslipidemia, Impaired fasting glucose, young, doctors, diabetes
CLINICAL AND HEMATOLOGICAL EFFECTS OF HYDROXYUREA THERAPY IN MANAGEMENT OF SICKLE CELL ANEMIA
Authors: Shukla Dr. Rajesh , Gajera Dr. Mehul 
Published: July 2019

Background: The most predominant form of haemoglobinopathy worldwide is sickle cell disease. The greatest burden of the disease lies in sub-Saharan Africa and Asia5.
Objective: To evaluate the effectiveness of HU therapy in sickle cell disease as measured by decrease in crises rate, hospital admissions, days of hospitalization and number of blood transfusions.
Methods: the study was conducted on 79 children of 1-16 year age. Out of which in only 75 patients Hydroxyurea therapy was started as they were found to be eligible. 16% of the patients responded to 15 mg/kg/ day of HU, 50.66% responded to 20 mg/kg/ day, 29.33% to 25 mg/kg/ day and only 4% needed a dose escalation to 30 mg/kg/ day for the response.
Results: Our study showed a significant reduction in the VOC rate from 243 episodes to 46 episodes (p value <0.001), the number of ACS reduced from 37 episodes to 5 episodes (p value <0.001), also there is a significant decline in the rates of hemolytic crises from 63 episodes to 10 episodes per year, Significant increase in the HbF levels from 15.87±5.50% to 21.77.±4.06% (p value <0.001). There was a definite and significant reduction in the number of hospitalization days from 7.76±4.76 to 3.79±2.29 days and in the number of admissions per year dropped significantly from 4.80 ± 1.41 to 1.42± 0.61 per year.
Conclusion: Hydroxyurea reduced the frequency of painful crises and diminished the number of hospitalization, transfusion, and episodes of acute chest syndrome17.
Keywords: Haemoglobin (Hb), Hydroxyurea (HU), Mean Corpuscular Volume (MCV), Pletelet Counts, Sickle Cell Disease (SCD), White Blood Cells (WBC).
Impacto de las redes sociales en el sector del enoturismo del Priorat
Authors: Quero Guerrero Joan , Caicedo Aldaz Julio Cesar , Cedeño Alcivar Lenin Landivar , Zúñiga Chamorro Cristian Roberto 
Published: July 2019

La eclosión del enoturismo ha supuesto para el sector vitivinícola catalán entrar en una nueva etapa dónde se tiene que comprender cuál es el producto que se espera, cómo lo espera el cliente y dónde tienen que ir las empresas a buscar a los clientes. Es un segmento en alza, que necesita de un trabajo constante y, a menudo, discreto. ¿Cómo pueden las redes sociales posicionar a
una empresa y diferenciarla del resto? ¿Lo están haciendo las empresas del Priorat? Uno de los ejes dónde aún se encuentran lejos de Burdeos o la Toscana es con el nivel de conexión con los clientes. En este trabajo analizaremos esta conexión des del punto de vista de las redes sociales, un paradigma aún por trabajar y que tiene dos hándicaps de primera mano. Así mismo Ylera (2007) define enoturismo como un fenómeno en el que los mundos del vino y turismo. Se funden para ofrecer una combinación de sus respectivas culturas, magias y atractivos. Otros autores mantienen la misma idea a la hora de definir el enoturismo como Imagen, ocio, cultura, salud y muchas cosas que acompañan al vino y que en cierto Modo todavía en España no se sabe aprovechar (Del Rey y Latre, 2007).
Procedimientos de planificación de la gestión de calidad como factor fundamental para el desarrollo de las universidades
Authors: Cárdenas Fragozo Norelys , Berrio Caballero Hobber , Alfaro Camargo Carlos 
Published: July 2019

Este capítulo presenta los resultados de un estudio realizado por los investigadores de la universidad de La Guajira. De la investigación que lleva por título “la innovación organizacional para la gestión de la calidad en las Instituciones públicas de Educación Superior del municipio de Riohacha –Colombia., lo cual indica según los resultados obtenidos que los procesos de planificación que se llevan a cabo son factores fundamentales para el desarrollo de las universidades. El objetivo se centró en describir los procesos de gestión de la calidad en las universidades públicas del municipio de Riohacha-Colombia. Cuya metodología fue de enfoque cuantitativo, diseño de campo de corte transversal y no experimental, descriptivo. La muestra estuvo constituida por 23 sujetos, distribuidos de la siguiente manera; decanos de las distintas facultades, coordinadores de programa, personal de la oficina de planeación, vicerrectoría de investigación y extensión, vicerrectoría académica de las universidades públicas del municipio de Riohacha, Se utilizó como técnica de recolección de datos la encuesta utilizando la escala Likert con cinco (5) alternativas de respuesta, mediante la distribución de frecuencia absoluta y relativa orientada a detallar en forma sistemática las características de la variable gestión de la Calidad. Los autores que soportaron la dimensión procesos de gestión de la calidad fueron Moreno (2001, Juran (2001), teniendo en cuenta el resultado final de la dimensión en la media fue de 4,2 ubicándose en la categoría presente en atención al baremo así mismo, la dispersión fue de 0,8 entendiéndose que hubo un nivel de dispersión alto, indicando esto que entre mayor es la dispersión hay esparcimiento en los datos. De acuerdo a este análisis, las universidades del municipio de Riohacha cuentan con un proceso de planificación donde se establecen, implementan, mantienen y mejoran continuamente un Sistema de Gestión de la Calidad (SGC), incluyendo los procesos necesarios y sus interacciones de acuerdo con los requisitos de esta norma.
Tubercular Lesions in Brain Parenchyma
Authors: Chowdhury Forhad Hossain , Mohammad Nur , Haque Mohammod Raziul , Hossain Zahed , Salam Md Abdus , Sarker Mainul Haque 
Published: July 2019

Background: Preoperative neuro-radiological features of tuberculosis involving brain lesions may mimic neoplastic lesions of brain & skull base and post operative histopathological study or response to empirical anti-tubercular therapy brings the ultimate diagnosis.
Objective: Here we present our experience of 76 cases of cerebral and cerebellar tuberculosis that was managed surgically with anti-tubercular drugs or medical treatment alone without histopathological confirmation.
Methodology: All cases of brain parenchymal tuberculosis confirmed histopathologically after surgery or confirmed by succesfull conservative treatment with anti-TB from January 2008 to June 2015 were included for study. Tubercular meningitis was excluded from the study. Patients underwent some form of surgery that confirmed the tuberculosis by histopathologically. Patients with suspected tubercular lesion in brain were treated empirically with antiTB. Post operative imaging was done with CT scan of brain or MRI of brain in immediate post operative period, six months after operation and 18 months after operation.
Results: 34 patients underwent surgery to confirm the tuberculosis and 44 patients with suspected tubercular lesion in brain were treated empirically with antiTB of which 40 patients responded successfully and rest 4 patients did not responded and underwent surgical excisional biopsy. Common clinical features include features of raised ICP with focal signs and symptoms. Concurrent other systemic tuberculosis was found in three cases. One patient had history of full course anti-tubercular therapy for pulmonary tuberculosis 20 years back.
Conclusion: In suspected TB lesions, conservative treatment without histopathological diagnosis may be adopted with ultimate same result
Bangladesh Journal of Infectious Diseases, December 2018;5(2):45-60
In New Geon Extra Peritioneal Caesarean Section An Observational Study
Authors: Daise Tahmina Afreen , Ara Begum Hosne , Tasnim Saria , Ahsan AKM Badrul , Chowdhury Sushmita Ray , Imran Shahed 
Published: July 2019

This study was designed to find out the maternal and perinatal outcome among 80 women undergoing extraperitoneal cesarean section. This observational study was conducted at Institute of Child and Mother Health, Matuail, Dhaka from 1st March 2013 to 28th February 2014. Data were collected by structured questionaire ith the writen consent of patients irrespective of routine and emergency cases where the procedure was successful in all patients. During operation, time was taken from open to close, incision to delivery of baby, total amount of blood loss during procedure, intraoperative complications, APGAR score of newborn were documented. Time required for return of bowel sound mobilization of patient within 24 hour and, duration of hospital stay were also included. Success rate of extra peritoneal CS was 100%, Time taken from incision to delivery was ≤6 minutes in 62.2% cases, time taken from incision to closure was between 31-45 min in 72.5% cases, blood loss ≤500 ml in 62% cases, return of bowel function between 5-8 hours in 52.5%, mobilization within 24 hours in 52.5%, neonatal one minute APGAR score ≥7 in 93.91%. As a surgical form of infection prophylaxis extraperitoneal cesarean section can be applied to avoid serious post-operative pelvic infections and its complications Extraperitoneal cesarean section would be a rational practice of cesarean section in the modern era.
Bangladesh Med J. 2017 Sep; 46 (3): 94-96
Case study of Dyadic death in Bangladesh: by Hanging, Strangulation and Poisoning
Authors: Sadek Ahmad , Halim Kazi Shafiqul 
Published: July 2019

Here described two cases where mother is the main perpetrators of the event and the victims were their children in the age group of 1 year to 12 years. In 1st case 35 years lady killed her three daughters ages 12, 9, 1 by strangulation then hanged in south surma Sylhet city. In 2nd case A 32 years old married women killed her two sons (ages 5 & 8yrs ) by poisoning and later she died by hanging in Sylhet city . Autopsy examination revealed ligature mark over neck consistent with that of antemortem hanging and ligature marks round the child’s neck were strangulation case also poison found by chemical examination. So it’s time to take awareness within community and take prevention such like notorious incident.
Bangladesh Med J. 2017 Sep; 46 (3): 104-106
Co-existence of Systemic Lupus Erythematosus and Ankylosing Spondylitis - A Case Report
Authors: Nakarmi Shweta , Ahmed Shamim , Shahin Md Abu , Shazzad Md Nahiduzzaman , Mahmood Tareq , Haq Syed Atiqul 
Published: July 2019

Co-existence of systemic lupus erythematosus and ankylosing spondylitis is not common. In this report, we present a 24-year-old woman with both the entities diagnosed in the course of time. Initially she presented with malar rash, photosensitivity, oral ulcer and polyarthritis. Her ANA and anti-Smith antibody were positive, but ant-ds DNA was negative. With these features, she was diagnosed as a case of systemic lupus erythematosus. Few months later, she was diagnosed with ankylosing spondylitis on the basis of inflammatory back pain and bilateral sacroilitis.
Bangladesh Med J. 2017 Sep; 46 (3): 100-103