bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Systematic Review of the Orthopaedic Literature Involving National Football League Players
Authors: Kluczynski Melissa A. , Kelly William H. , Lashomb William M. , Bisson Leslie J. 
Published: August 2019

Background: Orthopaedic injuries of National Football League (NFL) players can have a deleterious effect on their health, with minimal to no high-level evidence on the management of these injuries. Purpose: To summarize all data published between January 1980 and March 2018 on orthopaedic injuries experienced by NFL candidates and professional players in the NFL. Study Design: Systematic review; Level of evidence, 4. Methods: A literature search of studies examining orthopaedic injuries in the NFL was performed through the PubMed, Embase, and CINAHL databases. The review included studies of orthopaedic injuries in college football recruits attending the NFL Combine as well as professional NFL players. Excluded were studies of nonorthopaedic injuries, such as concussions, traumatic brain injury, facial injuries, and vascular injuries, as well as case reports. Results: A total of 147 articles met the inclusion criteria and were divided into 11 topics based on anatomic site: general (16%), spine (13%), shoulder (13%), elbow (3%), hand and wrist (3%), trunk (0.7%), hip and pelvis (7%), thigh (3%), knee (24%), ankle (5%), and foot (12%). Of these studies, 74% were of level 4 evidence. Most studies obtained data from the NFL Combine database (26%), by searching the internet (24%), and via the NFL Injury Surveillance System (22%). Studies using internet search methods to identify injuries consistently found fewer participants than studies using the NFL Injury Surveillance System. Conclusion: This systematic review provides National Collegiate Athletic Association and NFL team physicians with a single source of the most current literature regarding orthopaedic injuries in NFL players. Most research was published on knee, spine, shoulder, and foot injuries and consisted of level 4 evidence. A substantial portion of the published literature was based on data obtained from internet searches and may not accurately represent the NFL population.
Disease Models & Mechanisms in the Age of Big Data
Authors: Hatzopoulos Antonis K. 
Published: August 2019

ABSTRACT
In the decade since Disease Models & Mechanisms was launched, the emergence of Big Data as the main foundation of biological information is having a profound effect on how we do research and it has provoked some interesting questions. Is Big Data exploration replacing hypothesis-driven basic research? And, to what extent is disease modeling in the laboratory still relevant to medical research? Recent examples of synergistic approaches utilizing animal modeling and electronic medical records mining show that combining efforts between disease models and clinical datasets can uncover not only disease etiologies, but also novel molecular and cellular mechanisms linked to gene function.
Reviews
Authors: Chandna Mohit , Dasgupta Swati , Fox Rachel Gregory , Lee Vanessa , Miraglia Anne Marie , Miraglia Anne Marie , Morin Paul Max , Oktapoda Efstratia , Wandji Dieunedort 
Published: August 2019

The Colonial Fortune in Contemporary Fiction in French, Oana Panaïté (2017), Liverpool: Liverpool University Press, 216 pp., ISBN 978-1-78694-029-2, h/bk, £75
Post-Migratory Cultures in Postcolonial France, Kathryn Kleppinger and Laura Reeck (eds) (2018), Liverpool: Liverpool University Press, 296 pp., ISBN 978 1 78694 113 8, h/bk, £80
Postcolonial Poetics: 21st-Century Critical Readings, Elleke Boehmer (2018), London: Palgrave Macmillan, 220 pp., ISBN 978 3 31990 341 5, eBook, £47.99
Nouveaux entretiens avec Maryse Condé: écrivain et témoin de son temps, Françoise Pfaff (2016), Paris: Éditions Karthala, 197 pp., ISBN 978-2-81111-707-8, 19€
Les Lieux de mémoire de la guerre d’indépendance algérienne, Emmanuel Alcaraz (2017), Paris: Karthala, 322 pp., ISBN 978 2 81111 903 4, 24€
La Littérature haïtienne dans la modernité. De la conférence à la publication, Anne Marty (2017), Paris: Karthala, 276 pp., ISBN 978-2-81111-729-0, 25€
From Empire to Exile: History and Memory within the piednoir and harki Communities 1962–2012, Claire Eldridge (2016), Manchester: Manchester University Press, 352 pp., h/bk, ISBN 978 0 71908 723 3, £75.00
La Francosphère littéraire et l’empreinte française, Elena Prus (2012), Chişinǎu: ULIM, 236 pp., ISBN 978-9-97551-426-2
The End of the Cognitive Empire: The Coming of Age of Epistemologies of the South, Bonaventura de Sousa Santos (2018), London: Duke University Press, 392 pp., ISBN 978-1-47800-015-0, p/bk, £18
CD meets CAT
Authors: Kapovitch Vitali , Ketterer Christian 
Published: August 2019

Abstract
We show that if a noncollapsed

CD
⁢

(
K
,
n
)

{\mathrm{CD}(K,n)}

space X with

n
≥
2

{n\geq 2}

has curvature bounded above by κ in the sense of Alexandrov, then

K
≤

(

n
-
1

)

⁢
κ

{K\leq(n-1)\kappa}

and X is an Alexandrov space of curvature bounded below by

K
-

κ
⁢

(

n
-
2

)

{{K}-\kappa(n-2)}

. We also show that if a

CD
⁢

(
K
,
n
)

{\mathrm{CD}(K,n)}

space Y with finite n has curvature bounded above, then it is infinitesimally Hilbertian.
Bill of quantities and quantity survey of construction works of renovated buildings - case study
Authors: Lendo-Siwicka Marzena , Pawluk Katarzyna , Kowalczyk Arkadiusz , Trach Roman 
Published: August 2019

Abstract
The article presents detailed analysis of the case of the renovation of one of historic tenement houses in Warsaw. Other, similar cases analyzed in less detail- were called verification cases. The aim of the article was, first of all, to present the scale of discrepancies between planned and performed amount of works and possibly precise indication of the reasons for these underestimations. The scope of the research included the inventory of the technical condition of selected building elements, the execution of bill of quantities, quantity survey and cost estimates of selected works. The conducted research shows that quantity survey of works subjected to analysis such as: repair of walls, chimneys and brick walls reached the value at least twice as large. The planned cost of works calculated on the basis of the event was exceeded approximately twice. This was mainly due to the fact that the impact of repair works on deterioration of the technical condition of existing building elements was not foreseen. The poor technical condition of elements that were covered was not foreseen either. On the basis of the case studied, universal observations about renovated facilities can be provided. First of all, it should be stated that a person who makes bill of quantities on such facilities should have executive experience on similar projects. Thus, a good practice would be a cooperation with a person experienced in the implementation of similar investments.
Hyperboloid offset surface in the architecture and construction industry
Authors: Koźniewski Edwin , Borowska Anna 
Published: August 2019

Abstract
In this paper the issue of approximation of the hyperboloid offset surface off(S(t, v); d) at distance d by the hyperboloid surface S
1(ϕ, v) is considered. The problem of determining various surfaces approximating the hyperboloid offset surface off (S(t, v); d) is important due to the applications of the hyperboloid as a mathematical model for miscellaneous objects in the architecture and construction industry. The paper presents the method of determining the angles and coordinates of points of various surfaces approximating the hyperboloid of revolution. A two-sheet hyperboloid offset surface can be used for modelling double-layer domes. A one-sheet hyperboloid offset surface was used to model the reinforced structure of the cooling tower.
The “new” and “traditional” speaker dichotomy: bridging the gap
Authors: Hornsby Michael 
Published: August 2019

Abstract
This article analyzes the tensions and dynamics which exist between “new” speakers and other speakers, such as traditional or native speakers of minority languages (MLs), in an attempt to discover just how much of a barrier to communication are the (perceived) differences which are purported to exist between them. The dynamics between “new” and native speakers seem to be complex and nuanced, and “(in)authenticity” can be indexed through accent, the lexicon and grammatical structures, both by local users and more widely by researchers and other interested third parties, reflecting a wide range of ideo-logical stances. Using a critical sociolinguistic framework, these differences are examined from the perspective of the power differentials among and between various ML speakers/users in two situations of language endangerment, Breton and Yiddish. The reproduction of “symbolic violence”, as described by Bourdieu (1991), which results from such differentials can hinder language revitalization projects and can run counter to the interests of the language community in question. Both settings appear to share a commonality of experience that is wider than just the two language communities under scrutiny here and possible ways of reconciling such differences are examined toward the end of the article.
Interactions with Asians in Higher Education: Beyond Multicultural Myths
Authors: Obiakor Festus E. 
Published: August 2019

Abstract
One of the critical issues in education today is how to help all students to maximize their fullest potential. Achieving this goal seems to be difficult for many people who come from culturally and linguistically diverse (CLD) backgrounds. At all levels, they endure direct and indirect disenfranchisements, disadvantages, and disillusionments, especially if they learn differently, are racially different, demonstrate different behavioral patterns, have different personal idiosyncrasies, or come from different countries. Despite these apparent impediments, Asians are viewed by many as “model” minorities when compared to African Americans, Latinos, and Native Americans. This view has continued to affect how Asians view themselves and how the society as a whole views them. Coming originally from Nigeria to the United States, I have had myriad interactions with Asians as student, professor, scholar, leader, and professional. In this article, I share my experiences with Asians and how these experiences have exposed multicultural realities and myths.
Toxicity of secondary metabolites
Authors: Madariaga-Mazón Abraham , Hernández-Alvarado Ricardo Bruno , Noriega-Colima Karla Olivia , Osnaya-Hernández Adriana , Martinez-Mayorga Karina 
Published: August 2019

Abstract
Secondary metabolites, commonly referred to as natural products, are produced by living organisms and usually have pharmacological or biological activities. Secondary metabolites are the primary source for the discovery of new drugs. Furthermore, secondary metabolites are also used as food preservatives, biopesticides or as research tools. Although secondary metabolites are mainly used by their beneficial biological activity, the toxicity of some of them may limit their use. The toxicity assessment of any compound that is prone to be used in direct contact with human beings is of vital importance. There is a vast spectrum of experimental methods for toxicity evaluation, including in vitro and in vivo methodologies. In this work, we present an overview of the different sources, bioactivities, toxicities and chemical classification of secondary metabolites, followed by a sketch of the role of toxicity assessment in drug discovery and agrochemistry.
Combined approach of homology modeling, molecular dynamics, and docking: computer-aided drug discovery
Authors: Chahal Varun , Nirwan Sonam , Kakkar Rita 
Published: August 2019

AbstractWith the continuous development in software, algorithms, and increase in computer speed, the field of computer-aided drug design has been witnessing reduction in the time and cost of the drug designing process. Structure based drug design (SBDD), which is based on the 3D structure of the enzyme, is helping in proposing novel inhibitors. Although a number of crystal structures are available in various repositories, there are various proteins whose experimental crystallization is difficult. In such cases, homology modeling, along with the combined application of MD and docking, helps in establishing a reliable 3D structure that can be used for SBDD. In this review, we have reported recent works, which have employed these three techniques for generating structures and further proposing novel inhibitors, forcytoplasmic proteins, membrane proteins, andmetal containing proteins. Also, we have discussed these techniques in brief in terms of the theory involved and the various software employed. Hence, this review can give a brief idea about using these tools specifically for a particular problem.
Alternative Lengthening of Telomeres in the Budding Yeast Naumovozyma castellii
Authors: Cohn Marita , Andersson Ahu Karademir , Mateo Raquel Quintilla , Möller Mirja Carlsson 
Published: August 2019

Abstract
The enzyme telomerase ensures the integrity of linear chromosomes by maintaining telomere length. As a hallmark of cancer, cell immortalization and unlimited proliferation is gained by reactivation of telomerase. However, a significant fraction of cancer cells instead uses alternative telomere lengthening mechanisms to ensure telomere function, collectively known as Alternative Lengthening of Telomeres (ALT). Although the budding yeast Naumovozyma castellii (Saccharomyces castellii) has a proficient telomerase activity, we demonstrate here that telomeres in N. castellii are efficiently maintained by a novel ALT mechanism after telomerase knockout. Remarkably, telomerase-negative cells proliferate indefinitely without any major growth crisis and display wild-type colony morphology. Moreover, ALT cells maintain linear chromosomes and preserve a wild-type DNA organization at the chromosome termini, including a short stretch of terminal telomeric sequence. Notably, ALT telomeres are elongated by the addition of ∼275 bp repeats containing a short telomeric sequence and the subtelomeric DNA located just internally (TelKO element). Although telomeres may be elongated by several TelKO repeats, no dramatic genome-wide amplification occurs, thus indicating that the repeat addition may be regulated. Intriguingly, a short interstitial telomeric sequence (ITS) functions as the initiation point for the addition of the TelKO element. This implies that N. castellii telomeres are structurally predisposed to efficiently switch to the ALT mechanism as a response to telomerase dysfunction.
HEMŞİRELİKTE İNOVASYON KÜLTÜRÜ OLUŞTURMA; BİR BAŞARI ÖYKÜSÜ
Authors: DOĞAN MERİH Yeliz , ALİOĞULLARI Ayşegül , YAŞAR KOCABEY Meryem , GÜLŞEN Çiğdem , SEZER Aytül 
Published: August 2019

Amaç: Hemşireler hizmet sunumlarında etkin ve istendik sonuçları yakalayabilmek için sürekli değişime ayak uydurmak ve inovasyon sürecini hizmetlerine entegre etmek zorundadırlar. Hemşirelik hizmetlerinde inovasyon sürecini aktive etmek, hasta bakım maliyetini azaltırken, bakım kalitesini de artırmaktadır.Gereç ve Yöntem: Hastanemiz hemşirelik hizmetlerinde inovasyon sürecini aktive etmek için bazı basamaklar takip edilmiştir. İlk adımda hemşirelerimizin farkındalıklarını düzenli eğitimler ile bilgi düzeyleri arttırılmış, koçluk sistemi ile bireysel danışmanlıklar başlatılmış, süreci cazip hale getirecek yarışmalar düzenlenmiş, ödül süreci ile katılım arttırılmış ve hemşirelikte inovasyon kültürü oluşturulmuştur. Bulgular: Hastanemizde 2012 yılında başlatılan hemşirelikte inovasyonu aktive etme süreci dahilinde; yarışma ve sempozyum süreçleri gerçekleştirilmiştir. 7 yıllık süreçte hastanemiz hemşireleri toplam 376 inovatif proje geliştirmiştir. Her biri yeni bir buluş özelliği taşıyan projeleri ile hemşirelerimizin bakım kalitesini arttırıcı, yeni ve yaratıcı faaliyetleri desteklemeleri sağlanmıştır. İnovatif 50 proje için patent alma süreci tamamlanmıştır ve yeni buluşların üretimi için çalışmalar aktive edilmiştir. Sonuç: Hemşirelerde inovasyon sürecinin aktifleştirilmesinde; düzenli eğitimlerin, süreci tanıtacak, cazip hale getirecek, yol gösterecek bilimsel aktivitelerin yapılmasının ve rol model olmanın yeri büyüktür.
Репрезентация русской классики в западном мире: британская интерпретация «Евгения Онегина»
Authors: Шапинская Екатерина Николаевна 
Published: August 2019

<p>Статья написана на основе доклада на III Академических чтениях памяти Вл. А. Лукова «Тезаурусы и проблемы культуры», прошедшей в Московском гуманитарном университете 4 апреля 2019 г. Изучение взгляда на русскую культуру как на Другого важно как для самоидентификации культуры, так и для понимания ее универсальных, вечных сюжетов и образов. На примере интерпретации «Евгения Онегина» как литературного и музыкального текста проанализированы репрезентационные стратегии в отношении культуры Другого с точки зрения их важности для понимания культурной идентичности.</p>
Justification for preservation of the projected skin flap above the tumor during surgical treatment of primary resectable breast cancer
Authors: Khamitov A R , Ismagilov K Kh 
Published: August 2019

Aim. Improvement of the aesthetic outcomes of reconstructive plastic surgery for nodular breast cancer due to the scientific rationale of conservation of the projected skin flap and moving the postoperative scar to aesthetically acceptable zones.
Methods. Data of clinical and instrumental methods of investigation of 240 patients with primary resectable breast cancer were analyzed. The probability of involvement of the front layer of the superficial fascia in the projection of a malignant tumor depending on its clinical and topographic anatomical figures was estimated.
Results. The study revealed that the fascia involvement does not depend on the skin flattening. The skin flatte­ning is an indirect sign of superficial tumors having a probability of intimate adherence of the tumor to the fascia of 31.8±0.401%. In turn, the intimate adherence of the tumor to the front layer of the superficial fascia with a pro­bability of its involvement of 39.3±0.41% is a significant risk factor for the projected skin flap involvement. It was also found that involvement of the fascia studied does not depend neither on the size of the tumor, nor on the nodal status, nor on the biological subtype. The key risk factor is the depth of the tumor.
Conclusion. The indication for the projection skin flap preservation is the location of a malignant tumor at a depth of more than 1.05 cm, at which the probability of affecting the fascia is statistically insignificant and is 1.7±0.1%, which requires placing the subcutaneous tissue resection line in the tumor projection from the side of preserved skin flap.
Yenilikçi, Destekleyici ve Bürokratik Örgüt Kültürünün Pazar Odaklılık Üzerine Etkisi: Otel İşletmeleri Üzerine Bir Çalışma
Authors: ÇATIR Ozan 
Published: August 2019

Bu
çalışmanın amacı, yenilikçi, destekleyici ve bürokratik kültürün otel
işletmeleri bağlamında pazar odaklılık üzerindeki etkilerini incelemektir. Bu
araştırma için yöntem, tanımlayıcı olarak tasarlanmıştır. Uygulama için 312 anket
formu dağıtılmış ve elde edilen 242 anket formundan 226 tanesi değerlendirmeye
uygun görülmüştür. Anketlerden elde edilen veriler düzenlenerek istatistik
paket programında uygun analizler (ortalama, standart sapma, faktör analizi,
regresyon) yapılarak yorumlanmıştır. Çalışmanın
sonuçlarına göre, yenilikçi ve destekleyici örgüt kültürü boyutlarının pazar
odaklılık üzerinde pozitif yönlü bir etkisinin olduğu tespit edilmiştir.
Ayrıca, otel işletmeleri için mevcut olan örgütsel planlama ve pazarlama
seçeneklerinin geliştirilmesi ve örgüt kültürünü şekillendirmeye çalışan
yöneticilere pazar odaklılığın uygulanması ile ilişkili davranışlara rehberlik
edilmesi gerekliliği vurgulanmıştır.
THE PREDICTORS OF SPORTS TOURISM INVOLVEMENT IN MALAYSIA: AN EXTREME SPORT OVERVIEW
Authors: Hj. Ahmad Arman , Ibrahim Alisa , Hj. Ahmad Zulkarnian , Masri Ridzuan 
Published: August 2019

Purpose of Study: Malaysian tourism sector has widened its scope by venturing into extreme sports tourism. With this new development, tourism opportunities are created and boosting the Malaysian tourism industry growth. The study highlights the development of extreme sports destination that closely related to international and tourists’ involvement and preferences in Malaysia. The purpose of this paper is to determine the predictors of sports tourism involvement in Malaysia from the extreme sports perspective. Specifically, it is going to investigate the possible significant predictors that possibly influenced the international or local tourists’ preferences in choosing Malaysia as their preferred extreme sports tourism destination. This study is restricted to international or local tourists who participated or going to participate in extreme sports activities in Malaysia.
Methodology: This study proposes a theoretical framework that is developed based on the review of past researches and literatures. We identified five factors that possibly influenced international tourists or local tourists to choose Malaysia as their extreme sports tourism destination simultaneously involved in such activities. Those predictors are event popularity and entertainment, economics (costs and expenses), facilities and infrastructures, social, and environmental impact.
Results: The proposed hypotheses predicted a significant and positive relationship exists between event popularity and entertainment, economics (costs and expenses), facilities and infrastructures, social, and environmental impact towards the tourist involvement and sports tourism development in Malaysia. For the future research, we proposed to further conduct an empirical analysis to test these hypotheses.
Implications/Applications: This study could help tourism sectors to explore opportunities for development particularly in the extreme sports sectors in Malaysia. This study is also useful for researchers, students, tourism operators, tourism sectors, government and society because it could increase the involvement of international tourist or local into the extreme sports activities in Malaysia.
UNCERTAINTY AS AN ANTECEDENT OF THE SUPPLY CHAIN RISK: DOES SUPPLY CHAIN FLEXIBILITY MATTER IN RISK MITIGATION?
Authors: Sutduean Jutamat , Joemsittiprasert Watcharin , Jermsittiparsert Kittisak 
Published: August 2019

Purpose: This study aims to address the existing research gap, as well as to explore the various types of flexibility which could contribute in mitigating supply chain risks.
Methodology: In this regard, we consider three aspects under SCR namely; manufacturing process risk, delivery risk, and supply risk. The study explores the relationships among supply chain risk and environmental uncertainty, and the moderating role of supply chain flexibility by employing data of 91 manufacturing companies and develop a structural equation modelling.
Results: Developing economies are contributing well in the global trade and are responsible for 50% of the generated global output. They present future prospects for economic growth and pose challenges mainly because of immature supply chain operations. Considering the critical role of emerging economies in global supply chain, such as India and China, it is also important to observe the moderating and driving supply chain risk factors in these regions. It is assumed that this study will not only fill the existing gap in the literature of SCRM but will assist researchers and practicing managers, by enabling them to fully understand certain types of supply chain flexibility, thus reducing the SCR under business environments.