bluuebunny/crossref_metadata_2025_split huggingface dataset:
High prevalence of cesarean section delivery among health facilities delivered mothers in Bahir Dar city, Amhara region, Ethiopia. A comparative study
Authors: Melesse Meseret Bantigegn , Geremew Alehegn Bishaw , Abebe Solomon Mekonnen 
Published: August 2019

Abstract
Background

Cesarean section delivery prevalence rate has been in an alarming increase worldwide each year; there are large disparities of CS proportion among women who give birth at a public and private health facility. However, there is a lack of evidence regarding the underlying factors and the proportion of CS delivery in public and private health facilities. Therefore this study aimed to asses and compare the prevalence of CS delivery and associated factors among public and private health facilities delivered mother in Bahir Dar city, Amhara region, Ethiopia,

Methods

An institution-based comparative cross-sectional study design was conducted from March1-April 15, 2019 health facility in Bahir Dar city. Study participants 724(362 for each public and private facility) were recruited through a systematic random sampling technique. Structured interview administered questionnaires and chart review checklist were used to collect data. The data were entered with Epi info version 7.2 and analyzed using SPSS version 23.0 software. A binary logistic regression model was fitted and an adjusted odds ration with 95% CI was used to determine the presence and strength of association between independent variables and cesarean section delivery.

Results

The response rate was 98.3% and 97.2% for public and private health facilities respectively. The prevalence of CS in private health facilities was198 (56.3%) (95%CI: 50.9, 61.4) and 98 (27.5%) (95%CI: 22.8, 32.2) was in public health facilities. Overall prevalence of CS delivery was 296(41.8%) (95% CI: 38.4, 45.5). Breech presentation (AOR=3.64; 95%CI (1.49, 8.89), urban residence (AOR=6.54; 95%CI (2.59, 16.48) and being referred (AOR=2.44; 95%CI (1.46, 4.08)were variables significantly associated with CS among public facility whereas age between 15-24 (AOR=0.20, 95% CI; 0.07,0.52),governmental employee (AOR=2.28;95%CI (1.39,3.75),self-employed (AOR=3.73;95%CI(1.62,8.59),Para one(AOR=6.79;95%CI(2.02,22.79) Para two (AOR=3.88;95% CI(1.15,13.08), and wealth index being highest level of wealth asset AOR=5.39; 95%CI (1.08, 26.8) in private health facility:

Conclusion and recommendation

We concluded that there is a statistically significant difference in the prevalence of CS delivery in public and private health facilities. Therefore, there should be a mechanism for a medical audit of labor management.
Management Outcome of Uterine Rupture and Associated Factors in Yirgalem General and Teaching Hospital, Southern Ethiopia: A Cross-Sectional Study
Authors: Tekle Achamyelesh , Hagos Hailemichael , Tefera Kebede 
Published: August 2019

Abstract
Background

Uterine rupture is dropped significantly in the developed world. However, it is still a major public health problem in developing countries including Ethiopia. The aim of this study was to assess management outcome of uterine rupture and its associated factors in Yirgalem General and teaching Hospital of southern Ethiopia.

Methods

An institution based cross-sectional study was conducted. All records of uterine rupture managed in Yirgalem general and teaching hospital between January 1, 2012, and December 30, 2017, were reviewed. Data were collected using a checklist. Descriptive statistics and logistic regression analyses were done.

Results

A total of 331 cases of mothers who managed for uterine rupture were included in the study. 235 (71%) of them had a poor management outcome. Wound site infection 131 (39.6%) and anemia 129 (39%) where the common post-operative complications. There were 13 (4%) maternal death and 320 (96.7%) neonatal death. Lack of antenatal care follow up (adjusted odds ratio (AOR) =2.2, 95% CI: 1.1-4.5), prolonged duration of labor more than 24hr (AOR=3.6; 95% CI: 1.7-7.4), patients presented with sepsis (AOR=2.9; 95% CI: 1.4-6.1), mothers who did not transfuse for blood during the case scenario (AOR=4; 95% CI: 2.1-7.9) and prolonged intra operative time (AOR=5.5; 95% CI: 2.8-10.8) were factors associated with poor management outcome of uterine rupture.

Conclusion

Poor management outcome of uterine rupture was high in the study area as compared to other studies. Lack of ANC follow up, longer duration of the surgical procedure, prolonged duration of labor, lack of blood transfusion and pre and postoperative complications are associated with poor management outcome. Therefore, proper ANC and early identification of the high-risk groups can prevent and decline the occurrence of uterine rupture and that enhance good outcome.
Association Between Gastrointestinal Bleeding With Clinical Outcome On Acute Ischemic Stroke Patient
Authors: Amalia Lisda , Defryantho Rico , Parwati Ida , Ganiem Ahmad Rizal , Panigoro Ramdan 
Published: August 2019

Abstract
Background

Gastrointestinal bleedingis one of the complication of acute ischemic stroke and cause of increased mortality and length of stay. This is caused by a delay in the administration of antiplatelet or anticoagulant.Objective.To find the association between gastrointestinal bleeding with clinical outcome in acute ischemic stroke patient.Methods.This study was a prospective observational, conducted at Hasan Sadikin Hospital Bandung for 4 months (November 2017-February 2018). Acute ischemic stroke patients that fulfill the inclusion and exclusion were observed while being inpatients to observe their mortality and length of stay.This study used univariat, bivariat, multivariat, and stratification analysis.Results. A total of 100 acute ischemic stroke patients were found, and 24 patients had gastrointestinal bleeding. A history of previous peptic ulcer/gastrointestinal bleeding was found most often in patient with gastrointestinal bleeding (20.8%/p=0.003).Median NIHSS score is higher (16 vs 7/p<0.001) and GCS score was lower (12 vs 15/p<0.001) in patients with gastrointestinal bleeding. Multivariate analysis showed that gastrointestinal bleeding were significantly associated with survival (p = 0.021) and length of stay (p = 0.008). The analysis of stratification showed subjects with infections who later experienced gastrointestinal bleeding had a lower risk of death and length of stay than subjects without infection who experienced gastrointestinal bleeding (1.7 vs 22.5 times and 1.5 vs 2 times).Conclusion.Gastrointestinal bleeding had more increased mortality and length of stay than without gastrointestinal bleeding in acute ischemic stroke patient.
Performance of Xpert MTB/RIF Assay for Childhood Pulmonary Tuberculosis With Real World Evidence in China
Authors: Lu Shuihua , Xia Lu , Liu Xuhui , Qian Xueqin , Zhang Aimei , Li Tao , Xi Xiuhong , Zhang Yao , Liu Yuhong , Fan Xiaoyong , Liu Ping 
Published: August 2019

Abstract
BACKGROUND: Rapid and accurate notification of childhood pulmonary tuberculosis (PTB) is a worldwide challenge. Although the Xpert MTB/RIF assay (Xpert) has been endorsed as the initial test for suspected childhood pulmonary tuberculosis in many countries, limited studies have reported the real-world performance of Xpert for the detection of childhood PTB. OBJECTIVE: To evaluate the real-world performance of Xpert for the detection of childhood pulmonary TB in China. METHODS: We consecutively extracted the data of all patients ≤14 years with pulmonary disease through the electronic medical record (EMR) systems of Shanghai Public Health Clinical Center from January 2014 to December 2017. The clinical profile, the decision-making tests including AFB smear, solid/liquid culture, pathological examination and Xpert result were matched and assessed. The real diagnostic accuracy and the all-factors case notification rate for childhood PTB with the implementation of Xpert were evaluated. RESULTS: 519 cases ≤14 years with pulmonary disease were extracted from the data base. Of these, 145 had matched results, there were 374 non-matched cases including 346 with incomplete or unavailable data and 28 with NTM, BCG or an unidentified strain. For matched data, the overall sensitivity and specificity of the Xpert assay were 66.7% (32/48, 95%CI 0.52-0.80) and 87.6% (85/97, 95%CI 0.87-0.98) respectively against the gold standard; 34.6% (44/127, 95%CI 26.6-43.7) and 100% against the composite clinical reference standard (CCRS). The all-factors case notification rate by Xpert was 29%. CONCLUSIONS: Xpert/MTB RIF assay has acceptable sensitivity and excellent specificity for rapid diagnosis of children with pulmonary TB as well as for the detection of RIF resistance in China. However, implementation of Xpert for the initial diagnosis of childhood PTB is inadequate to meet the urgent requirement for rapid and accurate detection of childhood PTB.
Quantitative Proteomic Analysis of buffalo ovaries reveals the regulation of kinase and phosphatase during the Formation and Regression of Corpus Luteum
Authors: Zhang Ming , Ni Zhe , Fu Qiang , Pu Liping , Zhang Pengfei , Chen Dongrong , Yao Shun , Huang Fengling , Chen Fumei 
Published: August 2019

Abstract
Background: Reproductive characteristics are made up of many complicated physiology procedures that have significant effects on the growth of the buffalo industry and are affected by numerous factors. The ovary is the most important sexual organ of female mammals, and during the oestrous cycles, its corpus luteum (CL) plays a significant part in mammalian reproduction. During the development and regression of corpus luteum, however, the differentially expressed proteins are less defined. In this study, we used a 6-plex tandem mass tag (TMT) strategy for quantitative proteomic comparison of three distinct ovary phases (corpus hemorrhagicum, corpus luteum and corpus hemorrhagicum) in buffalo.
Results: A total of 148 differentially expressed proteins were identified, 32 of these proteins were identified as differentially expressed in the group CH (corpus hemorrhagicum) and 116 were identified as differentially expressed in the group CF (corpus fibrosum), with the group CL (corpus luteum) serving as the control group. Notably, we discovered that quite some enzymes such as kinase and phosphatase, are upregulated in the ovary CL phase, and three upregulated enzymes and proteins in the CL phase (PLK1, PGP, and HGS) were verified using Western blotting, quantitative RT-PCR, and immunohistochemistry analysis. The results of these validations were consistent with the quantitative analysis of the TMT-label, which indicated that they could play a crucial role during the CL's reproductive cycle. These buffalo results during the formation and regression of the corpus luteum are also shown to be a substantial reference value for comparable human and mouse studies after analyzing homologous BLAST cross-species. The expression information is accessible with the PXD009957 identifier via ProteomeXchange.
Conclusions: Our research gives a deeper understanding of CL formation and regression during the oestrous cycles, which shows kinase and phosphatase regulation, and indicates some potential enzymes and proteins that may influence buffalo fertility.
Keywords: corpus luteum, quantitative proteomic, oestrous cycles, ovary, cross-species
Combination Therapy Using Adipose-Derived Stem Cells And Low-Intensity Extracorporeal Shockwave Therapy On Erectile Dysfunction In Streptozotocin-Induced Diabetic Rats
Authors: Li Dankang , Ge Yongchao , Hou Quanliang , Wang Wenhua , Zhang Chengda , Ge Mengying , Tian Huizi , Zhao Qinglin , Godfrey Opolot , Zhang Weidong 
Published: August 2019

Abstract
Background：Diabetes mellitus (DM) is an important risk factor for erectile dysfunction (ED). Adipose-derived stem cells (ADSCs) and low-intensity extracorporeal shockwave therapy (LI-ESWT) are two emerging therapies for ED. The efficacy of ADSCs combined LI-ESWT in the treatment of diabetes induced erectile dysfunction (DMED) was not completely elucidated. This study aim to investigate combined therapeutic efficacy of ADSCs and LI-ESWT in rat model of DMEDand whether they have interaction.Methods：Rats were randomly divided into 5 groups: control, erectile dysfunction group (ED), ADSCs treatment group(ADSCs), LI-ESWT treatment group (LI-ESWT) and ADSCs combined with LI-ESWT treatment (ADSCs+LI-ESWT). After 4 weeks, erectile function was assessed using intracavernous pressure (ICP) and mean arterial pressure (MAP), after that performed immunohistochemistry (IH).Results：Finally, a total of 98 rats completed the experiment. The ICP/MAP of five groups under the voltage stimulation of 10V was significantly different (P>0.05). ICP/MAP in ADSC group, LI-ESWT group and combined treatment group was significantly higher than that of ED model group; ICP/MAP in combined treatment group was higher than ADSC group and LI-ESWT group. Interaction between LI-ESWT and ADSCs therapy was not statistically significant (P＞0.05).The expression of -smooth muscle actin (-SMA), nerve nitricoxide synthase (nNOS) and von Willebrand factor (vWF) in ADSCs treatment group, LI-ESWT group and combined treatment group was higher than those in ED model group (P < 0.05).Conclusions：Both ADSCs and LI-ESWT therapy can improve the erectile function of rats. The combination of these two methods present better effect on ED than used individually. There is no positive interaction between ADSCs therapy and LI-ESWT. Both ADSCs and LI-ESWT can enhance the expression of α-SMA, nNOS and vWF in corpus cavernosum of ED rats.
Costs of Responding to a Measles Outbreak: Buvuma Islands, Lake Victoria, Uganda, February-May 2017
Authors: Nguna Joyce , Bbaale Joy Kusiima , Birungi Doreen , Kwesiga Benon , Kadobera Daniel , Opar Bernard Toliva , Ampaire Immaculate , Luuze Henry , Kwesiga Brendan , Mwanje Wilbrod , Ario Alex Riolexus 
Published: August 2019

Abstract
Background

Despite the strong prevention efforts by the Uganda Ministry of Health (MOH), measles outbreaks continue to occur. The MOH responded to a measles outbreak in the hard to reach areas of Buvuma Islands, identifying 54 case-patients, 4 of whom developed complications and were hospitalized. We estimated the provider cost of responding to this outbreak, cost of prevention, and the cost the government would have saved with effective prevention.

Methods

We took the Government perspective into consideration. Using an itemized form, we systematically collected data on quantities and unit costs of all the resource inputs for both direct and indirect costs at national, district, and facility levels. Medical cost referred to hospital and clinic costs for medications, supplies, utilities, transport, and personnel; non-medical costs included those associated with person-hours spent on the outbreak investigation and control effort.

Results

The overall cost of investigating and controlling this outbreak was $16,259.50 (including $5,526.30) of medical costs, $10,733.20 of non-medical costs) and the cost per capita of number of children 6mon-5years was $117.80 (16,259.5/138 (number of children 6mon-5years. This is the target for measles intensified immunization following an outbreak).

Conclusion and Recommendations

The total cost incurred in this outbreak is four fold the amount needed to vaccinate all children in Buvuma which would have averted the outbreak. We recommend strengthening vaccination services in all corners of the country, especially hard-to-reach areas, to enable the government forego the extra cost and morbidity associated with outbreak control.
Distribution of primary site of hepatic metastases and prognosis of hepatic metastases at different primary sites
Authors: Li Huangbao , Zhou Jun , Zhao Fengqing , Cheng Quan , Zhu Xiang 
Published: August 2019

Abstract
Background
Most of the time, the primary tumor of hepatic metastases is easy to find. However, sometimes this is a confusing question. The present study aimed to explore the distribution of primary sites of hepatic metastases and the prognosis of hepatic metastases at different primary sites.
Methods
Data on patients with hepatic metastases were obtained from the surveillance, epidemiology, and end results (SEER) database between 2010 and 2016. Descriptive statistics was used to analyze the distribution of primary sites, life table to calculate survival rate, Kaplan-Meier method to plot survival curves, and Cox univariate regression and multivariate regression analysis to assess prognostic factors.
Results
The median age of 151,821 patients was 67 years; 58.7% of the primary sites were derived from the digestive system, followed by the respiratory system (25.6%) and other sites (15.8%). Ten leading primary sites were lung (25.4%), colorectum (24.1%), pancreas (19.8%), stomach (4.5%), breast (4.1%), gallbladder and biliary system (3%), esophagus (2.7%), kidney and renal pelvis (2.1%), ovary (1.8%) and primary sites unknown (2%). The overall survival probability of patients with hepatic metastases at 6 months, 1 year, and 3 years was 44.5%, 28.7%, and 9.9%, respectively, with a median survival of 4 months. The prognosis of hepatic metastases from lymphoma (Hodgkin and non-Hodgkin), the small intestine, breast, and colorectum was relatively better, and that from primary sites unknown, urinary system (bladder, urethra), lung, and pancreas was quite poor.
Conclusion
The distribution of primary sites of hepatic metastases was different under different grouping conditions, but the lung, colorectum and pancreas were the top three sources. The prognosis of hepatic metastases from different primary sites varied greatly.
What is the impact of husband’s education on unintended pregnancies in southern Ethiopia? A cross-sectional study
Authors: Seifu Canaan Negash , Fahey Paul Patrick , Hailemariam Tewodros Getachew , Atlantis Evan 
Published: August 2019

Abstract
Background: Unintended pregnancy rates are substantially higher in developing regions, have significant health consequences, and disproportionately affect subgroups with socio-economic disadvantage. We aimed to examine if husband’s education is associated with their wife’s unintended pregnancy in southern Ethiopia.
Methods: The data source for this study was from a cross-sectional study on iron-folate supplementation and compliance in Wolaita, South Ethiopia. Data were collected from 627 married pregnant women regarding their husband’s educational status, socio-demographic characteristics and if they wanted to become pregnant at the time of survey using an interviewer administered questionnaire. Odds Ratios (ORs) with associated z-tests and 95% confidence intervals and logistic regression analyses were used to identify variables associated with unintended pregnancy.
Results: The proportion of unintended pregnancy was 20.6% in this study with husband’s educational status, age, residence, and using family planning methods predictive of unintended pregnancy (all P-values <0.05). In the multivariable regression analysis, the odds of having unintended pregnancy was 60% lower (adjusted OR (95%CI; 0.4(0.18, 0.9)) when husband’s had University or College education compared to no education was after controlling for the age of women (adjusted OR per year older (95%CI); 1.13(1.09, 1.19)) and rural or urban residence (adjusted OR for rural (95%CI); 1.75(0.98, 3.12))
Conclusion: Unintended pregnancies were highest for women with less educated husbands in southern Ethiopia. We also found that being older and living in rural area were independently associated with an increased risk of unintended pregnancy. Strategies for addressing the family planning needs of families where husbands have less education should be the subject of future research.
Evaluation of patient satisfaction in hospitals in China 2003–2013: A national longitudinal analysis of population-based survey data
Authors: Tang Daisheng , Lian Ying , Dong Xuefan 
Published: August 2019

Abstract
Understanding the perception of patients towards the quality of hospitals is critical to policy development and improvement. However, there remains a dearth of literature examining the impact of the new health reform launched by China's government in 2009 on the changes of the patient satisfaction. Thus, the aim of this paper was to evaluate long-term trends in patient satisfaction to healthcare providers in China from 2003 to 2013. The data from three rounds (2003, 2008, and 2013) of the National Health Service Survey. The unsatisfactory rate, hospital satisfaction assessment and the most dissatisfied items for outpatients and inpatients in urban and rural areas in China were considered Percentages changes from 2003 to 2008, 2008 to 2013, and 2003 to 2013 were calculated to descriptively show the trends of patient satisfaction between these 10 years. Chi-square tests regarding the changes of each item between any two years were carried out to evaluate temporal variance. The results reveal a significant overall improvement in the patient satisfaction of both inpatients and outpatients in urban and rural areas in China from 2003 to 2013, especially for the period between 2008 and 2013. However, the percentage of outpatients who dissatisfied with the waiting time for treatment largely increased between 2008 and 2013. In addition, both inpatients and outpatients tended to pay more attention to the service quality and medical expense. With respect to the patient-physician trust relationship, an overall marked improvement could be identified. The findings of this study are unique in presenting the patient satisfaction at the national level in China, which highlight a need to carry out more national actions focusing on the optimization of visiting mechanism, the deduction of medical costs and the improvement of doctors' service and medical quality.
Strategic Planning for Public Sector Organizations: Evidence from The Department of Education and Culture in Kendal Regency
Authors: Aristyatama Hanung Adittya 
Published: August 2019

This paper aims to provide some evidence for current practice in strategic planning for public sector organizations developed by Rumelt's Criteria, in this case the Department of Education & Culture in Kendal Regency and propose a strategy for this Department. The data was collected from the Strategic Plan of the Department of Education & Culture in Kendal Regency from 2016-2021, Performance Reports 0f 2017, and the interviews from data collector in the Department of Education & Culture of Kendal Regency. The data analysis procedure used in this paper is a SWOT analysis based on data collected and developed into IFEM, EFEM, IE-Matrix, SWOT Matrix, and QSPM as the last step.
Intersecciones críticas de la modernidad en las ampliaciones teórico-metodológicas de Rodolfo Agoglia y Arturo Roig en los 70
Authors: Gatica Noelia Liz 
Published: August 2019

En las reflexiones teórico-metodológicas de Rodolfo Agoglia y Arturo Roig en los ´70 encontramos una crítica incipiente a la modernidad que se pone de manifiesto en la asunción del problema de las ideologías. Desde diferentes posicionamientos teóricos, el señalamiento de la posición de la conciencia en -y no por encima de- las contradicciones socio-históricas, se constituye en la advertencia de una racionalidad diferente de la lógica del capital que al tiempo que pone en discusión los alcances de la praxis intelectual, abre paso a la función utópica en la relación modernidad/alteridad.En esta ocasión, a partir del cruce entre la Historia de las Ideas y la Filosofía Práctica, nos enfocamos en dos aspectos: la denuncia de la irracionalidad de la violencia constitutiva de la racionalidad moderna todavía imperante en el discurso filosófico/científico/técnico y la posibilidad de una actualización diferente de la modernidad en su relación con la alteridad.