bluuebunny/crossref_metadata_2025_split huggingface dataset:
Faith and Spirituality in Naoko Takeuchi’s Bishōjo Senshi Sērā Mūn
Authors: Puglia Francesca 
Published: June 2019

Abstract
Bishojo Senshi Sera Mun has been an influential part of the childhood of many of the girls who grew up in the 1990s, both in Japan and in the rest of the world. Yet it is rarely examined in the context of its peculiar tragic and philosophic traits. The main objective of this study is to bring to light the deep spiritual and metaphysical thread of a work overflowing with religious and cultural references, specifying how both eastern and western traditions find their own way all along the story. While not denying the typical mahō shōjo topic of the magical girls, this article tries to show how the whole narrative can be read as a tangled metaphor of the inner and spiritual growth of the half-human and half-divine main character, Sailor Moon, whose infinite power resides in faith itself. As such, this article addresses the theme of this special issue, in exploring the superhuman abilities of Sailor Moon, focusing not so much on a humanist or posthuman framing but from the vantage of religious concepts of spiritual transcendence.
Enfrentamiento de la prensa de España y Francia por la cuestión marroquí en 1911 (Un nuevo capítulo de las disensiones entre los dos países) = Spain’s and France’s Press Confrontation about the Moroccan Question in 1911 (A New Chapter in the Dissensions between the Two Countries)
Authors: García de Juan Miguel Ángel 
Published: June 2019

Las disensiones vividas en Europa en el año 1911 a causa, aunque no sólo, del expansionismo colonial de varios de sus países en el norte de África estuvieron a punto de desencadenar, como es sabido, un conflicto bélico internacional. Es cierto que a finales de ese año y en 1912 distintos acuerdos en que participaron Francia, Alemania, España, el Reino Unido e Italia moderaron por un breve tiempo y de manera superficial su prepotencia y ansia de ampliación de dominios en el continente del sur.La tensión política entre Francia y España en 1911 por la cuestión africana ha atraído en España, si bien con no gran detalle, el interés de numerosos historiadores, pero no, que sepamos, el enfrentamiento entre la prensa de ambas naciones. Éste alcanzó una gran virulencia en muchos periódicos de los dos lados de los Pirineos (fuente principal de nuestra investigación). Recordar los hechos y, en especial, examinar su repercusión en los medios escritos es el principal objetivo del presente trabajo.Palabras claveColonialismo europeo; Marruecos en 1911; Tensión entre Francia y España; La prensa de ambos países. The disagreements that happened in Europe during 1911 because of the Colonial Expansion of several of their countries to North Africa, were about to unchain, as it is actually known, an international war conflict. It is true that, at the end of that year and for 1912, different agreements in which France, Spain, UK and Italy took part, reduced for a short period of time and in a superficial manner, their arrogance and anxiety for spreading their possessions along the continent of the south.The political tension between France and Spain during 1911 has attracted some historians but not, as far as we know, the confrontation between the media of both nations. It reached a great level of bitterness in many newspapers from both sides of the Pyrenees (main source of our investigation). Providing a comprehensive account of the facts and moreover investigating their impact in printed press is the main goal of this project.
Natural Product as the Storage medium for an avulsed tooth – A Systematic Review
Authors: R Rajakeerthi , MS Nivedhitha 
Published: June 2019

Dental avulsion is considered as one of the most
severe types of traumatic tooth injuries because it causes damage to several
structures and results in the complete displacement of the tooth from its
socket in the alveolar bone. The ideal situation is to replant the tooth
immediately after avulsion because the extra oral time is an important
determinant for the success of the treatment and for a good prognosis. The aim
of this systematic review was to identify the recommended natural storage m to
store and transport avulsed tooth based on the survival capacity of periodontal
ligament cells.This paper reviews the different storage media that
have been evaluated for avulsed teeth based on full-length research papers
retrieved from PubMed/Medline, Lilacs, BBO and SciELO electronic databases
using the key words ‘storage medium’, ‘avulsion’, ‘tooth avulsion’,
‘replantation’, ‘tooth replantation’, ‘milk’ and ‘propolis’. Based on the
application of inclusion and exclusion criteria, About 14 papers have been
selected and critically reviewed with respect to the characteristics, efficacy
and ease of access of the storage media. The review of this study shows and
includes a wide array of wet storage media that have been evaluated in
laboratory-based studies on PDL cells found on adult permanent teeth.

Among the natural products other than milk,
propolis, coconut water, green tea extract, egg white, green tea extract,
Alovera gel, pomegranate juice, salvia officinalis followed by dragon blood sap
(Croton Lechleri) were recommended based
on the cell viability and its longevity. In an emergency, it is important for
dentists to consider the circumstances of the accident, the location and
suggest an appropriate transport media.
Composition of Fatty Acids and Antioxidant Activity of Pomegranate Seed Oil CV. 'Molar'
Authors: Oliveira Ágda Malany Forte De , Araújo Railene Hérica Carlos Rocha , Alves Kalinny de Araújo , Onias Elny Alves , Candeia Roberlúcia Araújo , Lopes Maíra Felinto , Lima José Franciraldo De , Barbosa Luana da Silva , Dias George Alves 
Published: June 2019

Aims: Pomegranate has been used since ancient times as a universal therapeutic agent due to the presence of biologically active ingredients in different parts of the plant. Pomegranate seed oil is considered a nutraceutical because of its rich composition. Therefore, this work aimed to study the main changes in the composition of fatty acids and antioxidant activity of pomegranate seed oil (cv. Molar) in different stages of fruit development.
Study design: Completely randomized design. The treatments were the ages (60, 70, 80, 90 and 100 days), counted from the beginning of the anthesis. For each harvest a random sampling of five fruits was used for each repetition, and four replications per stage of fruit development were performed totaling 20 fruits per treatment.
Place and Duration of Study: The research was carried out in partnership with the farm Águas de Tamanduá, located in Várzeas de Sousa, PB, (longitude 38°13'41" and latitude 06°45'33").
Methodology: The characterization of the phenological phases of pomegranate (Molar cv.) development was carried out at the beginning of the orchard. Vigorous and healthy adult plants were selected. Hermaphrodite flowers were marked, evenly distributed in the area, with colored tape resistant to high temperature, sunshine, winds and rains. The marking of the flowers occurred in the early hours of the morning, and at the time of the marking, thinning of flowers was carried out on branches that had two or more flowers at the apex, leaving only a single flower on the branch. Seed oil was extracted from a sample of 20 fruits at different stages of development: 60, 70, 80, 90 and, 100 days counted from the start of the anthesis.
Results: The general composition of the oil of pomegranate seeds cv. Molar, regardless of the stage of fruit development, takes the order of PUFA> SFA> MUFA, with a higher content of polyunsaturated fatty acids (omega 3 and 6), and after saturated and monounsaturated, and low concentrations of total Trans Isomers.
Conclusion: The best periods for the consumption of pomegranate seed oil are between 80 and 90 days due to the higher amount of unsaturated acids and punicic acid, and lower concentrations of palmitic acid, as well as a higher concentration of phenolic compounds. The method of DPPH, with methanol extractor identifies the antioxidant activity of pomegranate seed oil, however not efficiently.
Organic Semiconductor Cocrystal for Highly Conductive Lithium Host Electrode
Authors: Park Jaehyun , Joo Se Hun , Kim Yoon‐Jeong , Park Ju Hyun , Kwak Sang Kyu , Ahn Seokhoon , Kang Seok Ju 
Published: June 2019

AbstractIn this work, a highly conductive organic cocrystal is investigated as an anode material for conducting agent‐free lithium‐ion battery (LIB) electrodes. A unique morphology of semiconducting fullerene (C60) and contorted hexabenzocoronene (cHBC) is developed as a cocrystal that efficiently enhances the electron transfer during discharge and charge processes due to the formation of a well‐defined junction between C60 and cHBC. In particular, the present study reveals the exact cocrystal phase of orthorhombic Pnnm using grazing incidence X‐ray diffraction characterization and computational methods. The detailed cocrystal structure analysis indicates that the columnar structure of C60/cHBC cocrystal facilitates the reliable vacant sites for Li+ storage, which ultimately enhances the reversible capacity to 330 mAh g–1 at 0.1 A g–1 with long cyclability of 600 cycles in the absence of a conducting agent. Furthermore, the rate performance of the C60/cHBC cocrystal anode is improved compared to that of the graphite anode, indicating that the cocrystal formation between C60 and cHBC enhances the charge transport at a high current density. It demonstrates that the approach of this study can be a promising strategy for preparing conducting agent‐free organic cocrystal anodes, which also provides a viable design rule for high‐performance LIBs electrodes.
Enhancing Prostate‐Cancer‐Specific MRI by Genetic Amplified Nanoparticle Tumor Homing
Authors: Zhao Yang , Peng Jing , Yang Jinyi , Zhang Enlong , Huang Ling , Yang Hong , Kakadiaris Eugenia , Li Jingjin , Yan Bin , Shang Zhiqun , Jiang Ning , Zhang Xuening , Han Gang , Niu Yuanjie 
Published: June 2019

AbstractPrecise localization and visualization of early‐stage prostate cancer (PCa) is critical to improve the success of focal ablation and reduce cancer mortality. However, it remains challenging under the current imaging techniques due to the heterogeneous nature of PCa and the suboptimal sensitivity of the techniques themselves. Herein, a novel genetic amplified nanoparticle tumor‐homing strategy to enhance the MRI accuracy of ultrasmall PCa lesions is reported. This strategy could specifically drive TfR expressions in PCa under PCa‐specific DD3 promoter, and thus remarkably increase Tf‐USPIONs concentrations in a highly accurate manner while minimizing their non‐specific off‐target effects on normal tissues. Consequently, this strategy can pinpoint an ultrasmall PCa lesion, which is otherwise blurred in the current MRI, and thereby addresses the unmet key need in MRI imaging for focal therapy. With this proof‐of‐concept experiment, the synergistic gene–nano strategy holds great promise to boost the MRI effects of a wide variety of commonly used nanoscale and molecular probes that are otherwise limited. In addition, such a strategy may also be translated and applied to MR‐specific imaging of other types of cancers by using their respective tumor‐specific promoters.
In Situ Modification of the Tumor Cell Surface with Immunomodulating Nanoparticles for Effective Suppression of Tumor Growth in Mice
Authors: Zheng Chunxiong , Wang Qixue , Wang Ying , Zhao Xinzhi , Gao Kaimin , Liu Qi , Zhao Yu , Zhang Zhanzhan , Zheng Yadan , Cao Jingjing , Chen Hongyun , Shi Linqi , Kang Chunsheng , Liu Yang , Lu Yunfeng 
Published: June 2019

AbstractCurrent cancer immunotherapies including chimeric antigen receptor (CAR)‐based therapies and checkpoint immune inhibitors have demonstrated significant clinical success, but always suffer from immunotoxicity and autoimmune disease. Recently, nanomaterial‐based immunotherapies are developed to precisely control in vivo immune activation in tumor tissues for reducing immune‐related adverse events. However, little consideration has been put on the spatial modulation of interactions between immune cells and cancer cells to optimize the efficacy of cancer immunotherapies. Herein, a rational design of immunomodulating nanoparticles is demonstrated that can in situ modify the tumor cell surface with natural killer cell (NK cell)‐activating signals to achieve in situ activation of tumor‐infiltrating NK cells, as well as direction of their antitumor immunity toward tumor cells. Using these immunomodulating nanoparticles, the remarkable inhibition of tumor growth is observed in mice without noticeable side effects. This study provides an accurate immunomodulation strategy that achieves safe and effective antitumor immunity through in situ NK cell activation in tumors. Further development by constructing interactions with various immune cells can potentially make this nanotechnology become a general platform for the design of advanced immunotherapies for cancer treatments.
Imaging Dynamic Peroxynitrite Fluxes in Epileptic Brains with a Near‐Infrared Fluorescent Probe
Authors: Hu Jiong‐sheng , Shao Chenwen , Wang Xueao , Di Xiaojiao , Xue Xuling , Su Zhi , Zhao Jing , Zhu Hai‐Liang , Liu Hong‐Ke , Qian Yong 
Published: June 2019

AbstractEpilepsy is a chronic neurodegenerative disease, and accumulating evidence suggests its pathological progression is closely associated with peroxynitrite (ONOO−). However, understanding the function remains challenging due to a lack of in vivo imaging probes for ONOO− determination in epileptic brains. Here, the first near‐infrared imaging probe (named ONP) is presented for tracking endogenous ONOO− in brains of kainate‐induced epileptic seizures with high sensitivity and selectivity. Using this probe, the dynamic changes of endogenous ONOO− fluxes in epileptic brains are effectively monitored with excellent temporal and spatial resolution. In vivo visualization and in situ imaging of hippocampal regions clearly reveal that a higher concentration of ONOO− in the epileptic brains associates with severe neuronal damage and epileptogenesis; curcumin administration can eliminate excessively increased ONOO−, further effectively protecting neuronal cells. Moreover, by combining high‐content analysis and ONP, a high‐throughput screening method for antiepileptic inhibitors is constructed, which provides a rapid imaging/screening approach for understanding epilepsy pathology and accelerating antiseizure therapeutic discovery.
Stochastic Memory Devices for Security and Computing
Authors: Carboni Roberto , Ielmini Daniele 
Published: June 2019

AbstractWith the widespread use of mobile computing and internet of things, secured communication and chip authentication have become extremely important. Hardware‐based security concepts generally provide the best performance in terms of a good standard of security, low power consumption, and large‐area density. In these concepts, the stochastic properties of nanoscale devices, such as the physical and geometrical variations of the process, are harnessed for true random number generators (TRNGs) and physical unclonable functions (PUFs). Emerging memory devices, such as resistive‐switching memory (RRAM), phase‐change memory (PCM), and spin‐transfer torque magnetic memory (STT‐MRAM), rely on a unique combination of physical mechanisms for transport and switching, thus appear to be an ideal source of entropy for TRNGs and PUFs. An overview of stochastic phenomena in memory devices and their use for developing security and computing primitives is provided. First, a broad classification of methods to generate true random numbers via the stochastic properties of nanoscale devices is presented. Then, practical implementations of stochastic TRNGs, such as hardware security and stochastic computing, are shown. Finally, future challenges to stochastic memory development are discussed.
Amorphous Gallium Oxide‐Based Gate‐Tunable High‐Performance Thin Film Phototransistor for Solar‐Blind Imaging
Authors: Qin Yuan , Long Shibing , He Qiming , Dong Hang , Jian Guangzhong , Zhang Ying , Hou Xiaohu , Tan Pengju , Zhang Zhongfang , Lu Yingjie , Shan Chongxin , Wang Jianlu , Hu Weida , Lv Hangbing , Liu Qi , Liu Ming 
Published: June 2019

AbstractGa2O3‐based solar‐blind photodetectors (PDs) are now attracting more and more attention for their potential application in optical imaging, spatial communication, etc. However, the performance of ever‐reported Ga2O3‐based PDs is still not good enough, strongly affected by either the Ga2O3 crystalline quality or the device structure, which severely limits their capability to detect extremely weak signals and achieve future applications. In this work, solar‐blind field‐effect phototransistor based on radio‐frequency‐magnetron sputtered amorphous gallium oxide thin film with ultrahigh photodetection performance are demonstrated. The key feature of the device is gate‐tunable photodetection enabling ultrahigh responsivity of 4.1 × 103 A W−1, external quantum efficiency of 2 × 106%, and detectivity of 2.5 × 1013 Jones under a 70 µW cm−2 weak signal of 254 nm light due to a high internal gain and field effect control of the phototransistor. Furthermore, high‐resolution imaging is achieved for the imaging target by integrating the as‐fabricated photodetectors into the imaging system, which is the first report on solar‐blind imaging of amorphous gallium oxide photodetectors. Such field‐effect phototransistors with ultrahigh performance and excellent imaging capability address a significant step toward the feasibility and practicability of gallium oxide photodetectors in solar‐blind imaging system.
Highly Selective Photoreduction of CO2 with Suppressing H2 Evolution over Monolayer Layered Double Hydroxide under Irradiation above 600 nm
Authors: Tan Ling , Xu Si‐Min , Wang Zelin , Xu Yanqi , Wang Xian , Hao Xiaojie , Bai Sha , Ning Chenjun , Wang Yu , Zhang Wenkai , Jo Yun Kyung , Hwang Seong‐Ju , Cao Xingzhong , Zheng Xusheng , Yan Hong , Zhao Yufei , Duan Haohong , Song Yu‐Fei 
Published: June 2019

AbstractAlthough progress has been made to improve photocatalytic CO2 reduction under visible light (λ>400 nm), the development of photocatalysts that can work under a longer wavelength (λ>600 nm) remains a challenge. Now, a heterogeneous photocatalyst system consisting of a ruthenium complex and a monolayer nickel‐alumina layered double hydroxide (NiAl‐LDH), which act as light‐harvesting and catalytic units for selective photoreduction of CO2 and H2O into CH4 and CO under irradiation with λ>400 nm. By precisely tuning the irradiation wavelength, the selectivity of CH4 can be improved to 70.3 %, and the H2 evolution reaction can be completely suppressed under irradiation with λ>600 nm. The photogenerated electrons matching the energy levels of photosensitizer and m‐NiAl‐LDH only localized at the defect state, providing a driving force of 0.313 eV to overcome the Gibbs free energy barrier of CO2 reduction to CH4 (0.127 eV), rather than that for H2 evolution (0.425 eV).
Bakterielle Diterpenbiosynthese
Authors: Dickschat Jeroen S. 
Published: June 2019

AbstractDieser Kurzaufsatz fasst die jüngsten Entwicklungen in der Biosynthese von Diterpenen durch Diterpensynthasen in Bakterien zusammen. Der Text ist nach der Klasse der am ersten Schritt zu den Diterpenen beteiligten Enzyme strukturiert und beginnt mit Diterpensynthasen des Typs I, gefolgt von Enzymen des Typs II, und schließt mit den kürzlich entdeckten, mit UbiA verwandten Diterpensynthasen. Ein Schwerpunkt liegt auf der Betrachtung der Reaktionsmechanismen von Diterpensynthasen, die einfache lineare Vorläufer über kationische Reaktionskaskaden zu strukturell komplexen, meist polycyclischen Kohlenstoffgerüsten mit multiplen Stereozentren umsetzen. Ein weiteres Hauptaugenmerk dieses Kurzaufsatzes liegt auf der Frage, wie diese Mechanismen aufgeklärt werden können. Auch nachgelagerte Modifikationen zu bioaktiven Molekülen werden behandelt.
Early postoperative seizures after vocal fold surgery attributed to shigellosis
Authors: Bregman Gennady , Lahav Yonatan , Kishinevsky Yelena , Grinevich Galina , Ezri Tiberiu , Dukhan Alexander 
Published: June 2019

SummaryA 44‐year‐old previously healthy woman underwent surgery of the vocal folds and developed early postoperative seizures caused by an unusual aetiology. Clinical assessment and laboratory results revealed that the patient suffered from an acute‐onset shigellosis infection which was thought to be the cause of her early postoperative seizures. The shigellosis infection was treated with azithromycin which resulted in rapid clinical improvement, and the seizures were successfully managed with benzodiazepines, sodium valproate and levetiracetam. To our knowledge, this is the first reported case of shigellosis‐induced seizures in an adult in the peri‐operative period. Early detection of the aetiology of seizures is crucial to ensure appropriate management and a safe patient outcome.
Reactive oxygen, nitrogen, and sulfur species in human male fertility. A crossroad of cellular signaling and pathology
Authors: Otasevic Vesna , Stancic Ana , Korac Aleksandra , Jankovic Aleksandra , Korac Bato 
Published: June 2019

AbstractInfertility is a significant global health problem that currently affects one of six couples in reproductive age. The quality of male reproductive cells dramatically decreased over the last years and almost every aspect of modern life additionally worsen sperm functional parameters that consequently markedly increase male infertility. This clearly points out the importance of finding a new approach to treat male infertility. Redox signaling mediated by reactive oxygen, nitrogen and sulfur species (ROS, RNS, and RSS respectively), has appeared important for sperm reproductive function. Present review summarizes the current knowledge of ROS, RNS, and RSS in male reproductive biology and identifies potential targets for development of novel pharmacological and therapeutic approaches for male infertility by targeted therapeutic modulation of redox signaling.
Metabolic engineering to improve 1,5‐diaminopentane production from cellobiose using β‐glucosidase‐secreting Corynebacterium glutamicum
Authors: Matsuura Rena , Kishida Mayumi , Konishi Rie , Hirata Yuuki , Adachi Noriko , Segawa Shota , Imao Kenta , Tanaka Tsutomu , Kondo Akihiko 
Published: June 2019

AbstractMicrobial production of 1,5‐diaminopentane (DAP) from renewable feedstock is a promising and sustainable approach for the production of polyamides. In this study, we constructed a β‐glucosidase (BGL)‐secreting Corynebacterium glutamicum and successfully used this strain to produce DAP from cellobiose and glucose. First, C. glutamicum was metabolically engineered to produce l‐lysine (a direct precursor of DAP), followed by the coexpression of l‐lysine decarboxylase and BGL derived from Escherichia coli and Thermobifida fusca YX (Tfu0937), respectively. This new engineered C. glutamicum strain produced 27 g/L of DAP from cellobiose in CGXII minimal medium using fed‐batch cultivation. The yield of DAP was 0.43 g/g glucose (1 g of cellobiose corresponds to 1.1 g of glucose), which is the highest yield reported to date. These results demonstrate the feasibility of DAP production from cellobiose or cellooligosaccharides using an engineered C. glutamicum strain.