bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of the Pipelines External Coating Technology Selection in the Definition of the Pipeline Design Strategy
Authors: Mantegazza Tommaso , Negro Francesco , Gildemyn Eric , Savazzi Marco , Esangbedo Jude , Piluso Rosangela , Bonetti Michele 
Published: August 2019

Abstract
In the upstream production systems, the external corrosion management typically does not affect the definition of the whole gathering network system design. However, its role is crucial for the integrity of any steel structure.
The external corrosion is generally managed with external coatings or cathodic protection systems designed to provide a durable protection against corrosive environments (either onshore or offshore). Typical external coating materials are polypropylene, polyethylene (in case of polyolefin coating), fusion bounded epoxy (FBE) or, in specific applications, thermal sprayed aluminium (TSA).
In High Pressure and High Temperature (HP/HT) reservoir applications, usually located in deepwaters offshore where the ambient temperatures are low (i.e. high temperature gradient between inside the pipelines and external environment), the selection of a specific external coating material might have significant impact on the design specification of the installed hardware, with special focus on the pipelines. In fact, depending on different physical properties of the external coating technologies, those may introduce stronger or weaker insulating capabilities and will modify the pipelines U Value, which describes the capacity of the pipelines to exchange heat with the external environment (and consequently the design specification of the production network).
A Case Study is here presented where impacts on the pipeline design specifications based on the selection of different external coating technologies have been described. In particular, it is here shown how the application of coating materials with lower insulating performance, e.g FBE coating, can increase the heat exchange between the hot production fluid and the cold external environment, leading to faster cooldown of production fluid.
In this case, reduction in operating fluid temperature has been used to prevent internal corrosion issues (generally linked to top of the line corrosion), however it may also be used as mitigation of HP/HT related issues, e.g. lateral buckling. Main pros and cons of FBE applied as a standalone external anticorrosion coating have been described in this paper.
Developing a Digital Twin: The Roadmap for Oil and Gas Optimization
Authors: LaGrange Elgonda 
Published: August 2019

Abstract
The Internet of Things (loT) has paved the way for significant efficiency gains in the oil and gas industry. One concept that has garnered significant attention is the "digital twin". However, there remains a great deal of confusion surrounding what a digital twin actually is and how it can be harnessed to add value to oil and gas operations. Some use digital twin as a synonym for their 3D plant models, others for their predictive maintenance solutions, or their simulation models. The bottom line is that the digital twin is all of these and more and unless operators look at it holistically, they are likely to miss out on some of the benefits.
Digital twins afford companies a number of advantages that would otherwise not be possible, including the ability to run risk analyses, health assessments, and what-if scenarios in real-time; the ability to train personnel in a 3D immersive, risk-free environment; and the capability to detect faults early before control limits are reached. This paper/ presentation will elaborate on how digital twins can be used to enhance efficiency and will address their use in the wider context of the oil and gas industry – with a particular focus on its impact on reducing risk and cost during both the project and operational phases of the asset lifecycle.
The objective is to demystify the digital twin, outline the advanced capabilities it enables and illustrate how oil and gas operators can use this concept to improve their competitive advantage.
Heavy metal levels, potential health risk, and uncertainty analysis in a plant–soil–irrigation system of the Yellow River irrigation area of northern Ningxia (China)
Authors: Liu Ping , Zhang Yahong , Feng Ningchuan , Zhu Meilin , Tian Juncang 
Published: August 2019

Abstract
Background Industrial development results in elevated levels of heavy metals in the local environment, including the air, soil, and water. These heavy metals can contaminate crops in the surrounding area, which may pose severe health risks to local inhabitants. The aims of this study were to determine the levels of heavy metals in plant–soil–irrigation system and the associated human health risk with deterministic and probabilistic approaches. Methods In this study, samples of soil, irrigation water, and maize crops were collected from the Yellow River irrigation area in northern Ningxia, China. Inductively coupled plasma-atomic emission spectrometry(ICP-AES)was applied to determine the heavy metal contents in maize grains, soil samples, and irrigation water. Potential health risks were assessed by deterministic and probabilistic estimation. Results The average concentrations of chromium and lead in maize exceeded the maximum allowable concentrations in food. The average concentrations of metals in the associated soil and irrigation water were both below the safe limits allowed in China. Deterministic estimation indicated a hazard index of 0.0986 for all inhabitants, implying no significant non-carcinogenic risk. The lifetime cancer risk value was 3.261×10−5, lower than the maximum acceptable level of 1×10−4 suggested by USEPA, while above the negligible level of 1×10−6 (USEPA) and 1×10−5 (WHO), with females facing a greater health risk than males. Probabilistic estimation indicated that approximately 0.62% of inhabitants are exposed to non-carcinogenic risk due to maize ingestion, while carcinogenic risk exceeds the maximum acceptable level (1×10−4) for 8.23% and negligible level (1×10−5) for 64.26% of inhabitants. Sensitivity analysis indicated that the concentration of arsenic in maize, the daily intake of maize, and exposure frequency of maize are the primary contributing factors in both non-carcinogenic and carcinogenic risks. Therefore, the content of arsenic in maize is of concern in the study region. Conclusions Based on deterministic and probabilistic risk estimation, there are no obvious non-carcinogenic health risks to inhabitants, while carcinogenic risk from As exposure is higher than the acceptable risk level. Females are at greater risk than males, and inhabitants under 20 years of age have the highest risk among age groups.
HIV testing experiences in Nairobi slums: The good, the bad and the ugly
Authors: Wekesa Eliud 
Published: August 2019

Abstract
[EXSCINDED] Background HIV testing is an integral component of HIV prevention, treatment and care and, therefore, is crucial in achieving UNAIDS 90-90-90 targets. HIV testing in Kenya follows both the voluntary counselling and testing (VCT) and provider initiated testing and counselling (PITC) models. However, little is known about the individual experiences of undergoing an HIV test in the two testing models. This study provides experiential evidence of undergoing an HIV test in a resource poor urban slum setting. Methods: The study explored testing experiences and challenges faced in respect to ensuring the 3 Cs (consent, counselling and confidentiality), using in-depth interviews (N=41) with HIV-infected men and women in two slum settlements of Nairobi City. The in-depth interview respondents were aged above 18 years with 56% being females. All interviews were audio-recorded, transcribed and then translated into English. The transcribed data were analysed using thematic analysis method. Findings: The respondent HIV-testing experiences were varied and greatly shaped by circumstances and motivation for HIV testing. The findings show both positive and negative experiences, with sporadic adherence to the 3Cs principle in both HIV testing models. Although some respondents were satisfied with the HIV testing process, a number of them raised a number of concerns, with instances of coercion and testing without consent being reported. Conclusion: The 3Cs (consent, counselling and confidentiality) principle must underlie HIV testing and counselling practices in order to achieve positive testing outcomes. The study concludes that adherence to the 3Cs during HIV testing contributes to both the individual and public health good – irrespective of whether testing is initiated by the individual or by the health provider.
Overexpression of GmNFYA5 confers drought tolerance to transgenic Arabidopsis and soybean plants
Authors: Ma Xiao-Jun , Yu Tai-Fei , Li Xiao-Hui , Cao Xin-You , Ma Jian , Chen Jun , Zhou Yong-Bin , Chen Ming , Ma You-Zhi , Zhang Jun-Hua , Xu Zhao-Shi 
Published: August 2019

Abstract
Background: The crop productivity is challenged by abiotic stresses, among which drought stress is the most widespread . The NF-Y genes, especially NF-YA genes function in regulating drought tolerance of plants.
Results: In this study, a soybean NF-Y gene, GmNFYA5 , was identified with the highest transcript level among all of 21 NF-YA genes in soybean ( Glycine max L.) under drought stress. Transcript of GmNFYA5 induced by drought was suppressed by ABA synthesis inhibitor naproxen (NAP). GmNFYA5 transcript was detected in various tissues at vegetative and reproductive growth stage with higher levels in roots and leaves, which was consist with the GmNFYA5 promoter:GUS fusion assay. Overexpression of GmNFYA5 resulted in increased drought tolerance and ABA sensitivity in transgenic Arabidopsis plants. Additionally, overexpression and suppression of GmNFYA5 in soybean resulted in increased and decreased drought tolerance compared with empty vector (EV) plants respectively. Transcript levels of ABA-dependent and ABA-independent genes in transgenic Arabidopsis and soybean plants overexpressing GmNFYA5 were higher than those of WT and EV plants under drought stress respectively, but the opposite results were detected in soybean plants suppressing GmNFYA5 . Furthermore, GmNFYA5 might regulate the expression abundance of GmDREB2 and GmbZIP1 by binding the promoter in vivo.
Conclusions: These results suggest that overexpression of GmNFYA5 can improve drought tolerance via ABA-dependent and ABA-independent pathways in soybean.
World Delirium Awareness Day 2019, delirium and risk of falls in the hospital setting
Authors: Shekhar Rozina , Rolls Kaye Denise , Chasle Briony , Stott Katrina , Vueti Vaulina , Deane Vicki , Edmonds Renee , Moseley Margaret , Shepherd Bernadette , Mayahi-Neysi Mandana , Wilson Carol , Sandu Novjot , Phillips Jennifer , Marov Lynda , Carr Sara , Richardson K’Sandra , McGuire Kathy , Gujraz Poumansing , Kumar Binita , Jankulovski Daniella , Dixon Kylie , Lata Yashwani , Zachariah Rinsy , Warner Bradley , Frost Steven A 
Published: August 2019

Abstract
Background

Delirium is an acute change in cognition, common among older hospitalized patients, however, patients of all ages are at risk of delirium during a hospital stay. The International Federation of Delirium Societies promotes, each year, a World Delirium Awareness Day, to raise the awareness of, not just recognizing delirium in the hospital setting, but ensuring interventions are in place to prevent the development of delirium. Hospitalized patients with delirium have increased risk of adverse events such as falls, pressure injury, malnutrition, increased length of stay, increased health care costs, and mortality. This clinical audit aimed to estimate the risk of a subsequent fall, following an acute episode of in-hospital delirium, across a broad cross-sectional of clinical settings.

Methods

Seventeen adult acute inpatient wards across a health district, undertook an audit of the number of admitted patients who had had at least one episode of delirium since being admitted to hospital. Using the hospital-based incident management reporting system, the rates of subsequent falls was compared between delirium and non-delirium patients.

Results

Fifty of the 473 patients (11.4%) were identified by the nursing staff to have had at least one episode of delirium since admission. The proportion of fallers among the delirium and non-delirium patients were 10% and 2%, respectively (p = 0.004). The rate of falls per 1000 patient days was 6.45 (95% confidence interval (CI) 2.1 to 15.1) among delirium patients, compared to 2.12 (95% CI 1.0 to 4.0) among patients without delirium. The risk of falling among delirium patients was 4.25 higher compared to non-delirium patients (adjusted hazard ratio (HR) = 4.25, 95% CI 1.26 to 14.39).

Conclusion

This clinical audit has been able to show that an acute episode of delirium increases the risk of an in-hospital fall fourfold. Importantly, these results have highlighted the need for a hospital wide approach, to not just in identifying delirium, but the need to have interventions in place to reduce the risk of delirium. In other words, delirium prevention should be ‘core business’ of all nursing care, across the acute hospital setting.
A scoping review on the influencing factors and development process of professional identity among nursing students and nurses
Authors: mao aimei , Lu Su-e , Lin Yan , He Miao 
Published: August 2019

Abstract
Background Professional identity is related to individuals’ professional commitment. It has been a hot topic in the nursing science because of the common problem of nursing workforce shortage around the world. Professional identity is culturally shaped, but few scholars have systematically examined its developmental characteristics in a specific culture. The aim of the scoping review is to get comprehensive knowledge on the influencing factors and development process of the professional identity among nursing students and nurses in mainland China Methods A scoping review was conducted. The most common Chinese databases, China National Knowledge Infrastructure and Wanfang Data, were searched for publications in Chinese. The EBSCOhost and ProQuest dissertation and thesis global were searched for publications in English. After screening the title and abstract of the articles in the first round and the full-text in the second round, 53 articles were included for analysis. Results The influencing factors to professional identity development in nursing could be grouped into three dimensions: personal factors at micro dimension, familier factors and institutional factors at medium dimension, and social factors at macro dimension. The social factors tended to negatively affect professional identity while the factors at the other two dimensions exerted influence in different directions. A framework was established based on professional identity levels in different career stages of nurses to depict the continuum and dynamic nature of development process. Conclusions Development of professional identity in nursing is a dynamic process shaped by multidimensional factors. The biggest obstacles to the development lie in the social factors. Changes in policy should be made to reverse the nursing profession stereotype of being a passive role to medicine. As some obstacles and challenges faced by nursing are shared by nurses around the world, international cooperation is needed to address the common obstacles and challenges. Keywords: China; development process; influencing factors; nurses; nursing students; professional identity; scoping review
Characterization of gut microbial community of rhesus macaques under the high-altitude extreme environments
Authors: Wu Yuhan , Yao Yongfang , Dong Mengmeng , Xia Tianrui , Li Diyan , Xie Meng , Wu Jiayun , Wen Anxiang , Wang Qin , Zhu Guangxiang , Ni Qingyong , Zhang Mingwang , Xu Huailiang 
Published: August 2019

Abstract
Background: The mammal intestinal microbita involved in various physiological processes in host and play a key role in host environment adaption. However, for non-human primate(NHP), little is known about their gut microbial community in high-altitude extreme environment and much less to their adaption to high-altitude environment. In this study, we want to characterize gut microbial community of rhesus macaques from multiple high-altitude environment and by comparing it to low-altitude control group to reveal the differences between altitudes.
Results: we collected the fecal samples of rhesus macaques from four high-altitude populations (above 3000m) and one low-altitude population (below 100m). We first analyzed the overlap of operational taxonomic units (OTUs) between populations and found 27.8% of OTUs (core OTUs) were shared by all five population.The majority of these OTUs have a higher abundance, whereas the unique OTUs have a lower abundance. By calculating alpha diversity index, we found high-altitude populations exhibited higher diversity. Statistical analysis of beta diversity indicated there were significant difference between high and low altitude population. Significant difference in composition were detected at phylum and family. At phylum level, high-altitude gut microbial community were dominanted by Firmicutes(63.7%), but low-altitude were dominated by Bacteroidetes(52.2%). At family level, high-alititude population were dominanted by Ruminococcaceae(36.4%), but low-altitude were dominated by Prevotellaceae(43.9%). Additionally, the abundance of Christensenellaceae are significantly higher in all high-altitude populations(3.33%) than low-altitude population(0.77%), despite a low abundance in two altitudes. Finally, function prediction indicated there was a significant difference in gene copy number of 29 level-2 pathway between high and low altitude population; and 26 of them are higher in high-altitude, especially in membrane transport and carbohydrate metabolism.
Conclusions: We found the gut microbial community of high-altitude rhesus macaques is significantly distinct from low-altitude population in diversity, composition and function. High-altitude populations were dominanted by Firmicutes and Ruminococcace, but low-altitude population by Bacteroidetes and Prevotellaceae. The difference in gut microbiota between two altitude macaque populations may be caused by different host diet, environmental temperature and oxygen pressure, and gut microbial microorganisms may play an critical role in adaptive evolution of rhesus macaques to high-altitude environment.
Ageing-related bacterial features in different segments of the mice gastrointestinal tract
Authors: Zhou Qi , Sun Liang , Li Linfang , Gong Huan , Zhang Ying , Chen Chen , Li Jian , Yang Ze 
Published: August 2019

Abstract
Background: Ageing is associated with alternations of gastrointestinal (GI) microbiota according to metagenome sequencing. However, the most commonly used sequencing samples were from feces, therefore it remains unknown how the upper gastrointestinal microbiota changes with age and to what extent the fecal can represent the gastrointestinal microbiota. To investigate associations between the microbiota of whole GI tract and ageing, we compared microbial diversity and composition of six GI segments in different phenotypes with a mouse model.
Results: Microbial α and β diversity were significantly different between the upper and lower GI tract. The jejunum and ileum samples had significantly lower phylogenetic diversity than large intestinal and stomach did (P < 0.01). About 22.9% core OTUs (n=80) were shared by the whole GI tract, and fecal represented significantly higher microbiota with content from large intestine than content form upper GI tract (82.7% vs. 65.2%, P <0.001). Sutterella, Aggregatibacter, Lactococcus, Lactobacillus and Streptococus were significantly enriched in the upper GI tract, while 14 anaerobes such as Ruminococcus were significantly enriched in the lower GI tract (P < 0.05). The elderly mice had the significant microbial dissimilarity (both in α and β-diversity) with the young- and middle-aged ones. These differences were dependent on GI segments; especially in the lower GI tract, more obvious variations were found. However, the age-associated change was smaller when it compared with the high-fat diet treated mice.
Conclusion: The GI microbiota was gradually changed with age and the changes were affected by GI segments. The microbial interactions with host motivate future studies exploring the specified GI microbiota interventions of disease.
Keywords: Healthy ageing, Gut microbiota, 16S rRNA sequencing, Gastrointestinal tract, mice
Studies on the Prevalence of Hepatitis C Virus Infection in Diabetic Patients.
Authors: Ndako James A. , Owolabi Akinyomade O , Olisa Joseph A. , Akinwumi Jeremiah A. , Dojumo Victor T. , Olatinsu Oludolapo , Adebayo Blessing A. 
Published: August 2019

Abstract
Background: Hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM) are two major public health problems associated with increasing complications and mortality rates worldwide. The objective of this study to evaluate the prevalence of hepatitis C virus (HCV) infection in diabetic patients and to investigate the influence of several epidemiological and clinical factors on HCV infection. Method: A total number of one hundred and eighty diabetic patients were recruited for this study. Consented subjects made up of 71(39.4%) males and 109(60.56%) females were recruited for the study. Structured questionnaires were administered to the consented participants to obtain relevant data. Sera samples were assayed for antibodies to HCV using an enzyme linked immunosorbent assay [Inteco Diagnostic Limited]. ELISA technique. Result: Overall prevalence of HCV infection among diabetes patients assayed was 13.3%. Out of which 8(11.3%) was obtained from the male subjects compared to 16 (14.7%) seropositivity recorded for the female subjects (P = 0.511; P > 0.05). Considering age distribution, Subjects aged 41-50 years recorded, 9 (22.5%) positivity (P= 0.238; P>0.05).Considering educational status of subjects screened, 22 (14.9%) positivity was rescored among subjects who have attained tertiary status of education.( P = 0.574;P>0.05).Risk factors considered showed that, 7 (18.9%) seropositive subject were alcoholic consumers(P value = 0.2621;P>0.05) while 5 (8.9%) recorded history of sharing sharp objects P= 0.2427;P>0.05). Conclusion: Our study shows a slightly higher prevalence of hepatitis C infection in type 2 diabetics. This call for urgent routine screening exercise among diabetic patients for HCV infection. This study also emphasizes the need for public enlightenment of the association between HCV infection and T2DM, to avert possible complications among diabetic patients. Keywords: HCV, Type 2 diabetes mellitus (T2DM), Patients