bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of serum potassium ion variability on 28-day mortality in ICU patients
Authors: Zhang YuChou , Liang ShengDe , Wen HanChun 
Published: November 2024

Objective
Potassium ion disorders are prevalent among patients in Intensive Care Units (ICUs), yet there is a notable deficiency in established protocols and supplemental plans for potassium management. This retrospective study conducted at a single center aims to explore the relationship between potassium levels, their variability, and the 28-day mortality rate in ICU patients.

Methods
This study analyzed data from patients admitted to the ICU of the First Affiliated Hospital of Guangxi Medical University between October 2022 and October 2023. We assessed serum potassium variability using the coefficient of variation and categorized it into four quartile groups (Q1, Q2, Q3, Q4). Additionally, patients were classified into six groups based on serum potassium concentrations. The associations between these categories and the 28-day mortality rate were evaluated using binary logistic regression, adjusting for potential confounders.

Results
A total of 506 patients and 12,099 potassium measurements were analyzed. The group with the lowest potassium variability (Q1) exhibited the lowest mortality rate at 21% (P<0.01). It is noteworthy that within 28 days in the intensive care unit (ICU), the coefficient of variation (CV) of potassium levels significantly increased among deceased patients compared to surviving patients (P < 0.01).

Conclusion
Significant variability in potassium levels is associated with an increased risk of 28-day mortality among ICU patients, underscoring the need for stringent monitoring and management of potassium levels in this population.
Comparison of hematologic parameters, serum electrolytes, and lipid profiles among dyspeptic patients with and without Helicobacter pylori infection attending Jimma Medical Center, Jimma, South West Ethiopia
Authors: Sarbecha Negussie , Fikade Minale , Wondimnew Tesaka , Kene Kumsa , Kebede Negawo , Gebresillasie Habtemariam , Assefa Zerihun 
Published: November 2024

Background
About half of the world’s populations are infected with Helicobacter pylori, which may create atherogenic lipid profiles and contribute to atherosclerosis and related cardiovascular disease. Furthermore, it has been connected to hematological symptoms like anemia. Even though the high prevalence of H.pylori and its associated complications, including cardiovascular disease and anemia, in Ethiopia, there is little data regarding the risk factors associated with H.pylori infection, such as hematologic parameters, electrolyte imbalances, and lipid profiles.

Methods
A comparative cross-sectional study design with a consecutive sampling technique was employed at Jimma Medical Center among 108 dyspeptic patients. Five (5) ml of blood samples were collected from each participant, and serum was extracted and analyzed using a COBAS 6000 core for the lipid and electrolyte, and whole blood was used with a SYSMEX XN 550 to determine hematological parameters. Data were entered in to Epi-data version 4.6 and exported to SPSS version 25 for analysis. Simple descriptive statistics and chi-square test were used to present the socio-demographic characteristics of the study subjects. Student t-test was used for data comparison and p-value < 0.05 was considered statistically significant.

Results
H.pylori infected patients had significantly decreased levels of red blood cell count (p = 0.002), hemoglobin (p = 0.012), mean corpuscular hemoglobin concentration (p < 0.001), platelet count (p = 0.001), and sodium level (p = 0.006) when compared to the uninfected group. However, total cholesterol (p = 0.001), and low density lipoprotein (p = 0.021) were increased in H.pylori infected patients when compared to the uninfected group.

Conclusions
This study revealed that H.pylori infection can cause derangements of hematologic parameters, electrolyte imbalances, and alterations of lipid parameters which considered as risk factors for anemia and cardiovascular diseases.
Correlations between nutritional indicators and cognitive function in patients with stable schizophrenia in a hospital setting
Authors: Wang Binyou , Zhou Yong , Yu Han , Jiang Techeng , Liu Kezhi , Pu Jianlin , Wang Yilin 
Published: November 2024

Background and objectives
Cognitive impairment is a core feature of schizophrenia, and it is now clear that there is a link between nutritional indicators and cognitive functioning. This study aimed to investigate correlations between three nutritional indicators (prognostic nutritional index [PNI], geriatric nutritional risk index [GNRI], and controlling nutritional status score [CONUT]) and cognitive function in hospitalized patients with stable schizophrenia.

Methods
A total of 235 patients who were hospitalized with stable schizophrenia were included. Patient demographic information was collected through self-reports or electronic medical records, and cognitive function was assessed using the Montreal Cognitive Assessment in China (MoCA-C). Information on serum albumin and total cholesterol levels, lymphocyte counts, and body mass index during the stable stage of schizophrenia was collected to calculate the PNI, GNRI, and CONUT scores, according to their respective calculation criteria. Covariate-adjusted linear regression model and ordered logistic regression model were constructed to determine the relationship between nutritional indicators and cognitive function.

Results
Overall, 90.2% of the patients were under the age of 60 years, and males comprised 60% of all patients. The median scores for MoCA-C, PNI, GNRI, and CONUT in hospitalized patients with stable schizophrenia were 18 (12,23), 52.85 (50.25,55.90), 110.85 (105.80,116.21), and 3 (3,3), respectively. The results of the correlation analysis showed that only PNI was associated with MoCA-C scores (r = 0.15, P = 0.021). This relationship was further confirmed by covariate-adjusted linear regression modeling (β = 0.147, 95%CI:0.049–0.351, p = 0.01) and ordered logistic regression modeling (OR = 0.054, 95%CI:0.001–0.106, p = 0.046).

Conclusions
The findings revealed a significant correlation between PNI scores and MoCA-C scores in hospitalized patients with stable schizophrenia.
Time to recovery following cataract surgery and its predictors among patients undergoing surgery at two selected Public Hospitals in Hawassa, Sidama, Ethiopia
Authors: Sarmiso Shilota , Tediso Dansamo , Tafese Temesgen , Gari Taye 
Published: November 2024

Background
Cataract surgery is a commonly performed procedure aimed at restoring vision in individuals affected by cataracts. The duration of recovery following cataract surgery can vary among patients and is influenced by a multitude of factors. Therefore, the purpose of this study was to determine the time to recovery from cataracts and its predictors among patients treated with cataract surgery at two selected Public Hospitals in Hawassa, Sidama regional state, Ethiopia.

Methods
Institution-based retrospective cohort study was conducted among 444 cataract patients treated with surgery from January 01, 2019, to December 30, 2021. A simple random sampling method was used to select two public hospitals. The data was collected using Kobo toolbox Version 4 and trained data collectors. STATA Version 16 was used for analysis. To estimate the recovery time and compare survival probability among variables Kaplan-Meir curve and Log-rank test were used. The cox-Proportional hazards model was used to identify significant predictors of time to recovery. The association was reported using the adjusted hazards ratio (AHR) with a 95% confidence interval (95%CI), and the significance level was set at a p-value of 0.05.

Results
This study showed that 76.14% of cataract patients recovered from cataracts. The average time taken to recover from a cataract was 30 weeks (IQR = 15 to 48) 95%, CI, (26–33). Age 40–60 years (AHR = 2.04 CI; 1.12–3.82), urban dwellers (AHR = 1.48; 95% CI, 1.13–1.93), medium/high level of visual acuity (AHR = 1.49 CI; 1.14–1.94), secondary cataract (AHR = 1.56 CI; 1.11–2.18) and traumatic cataract (AHR = 1.82 CI; 1.32–2.52) were associated with time to recovery of cataract patients.

Conclusions
According to this study, the time to recovery of cataract patients was slightly high. Cataract patients’ time to recovery was affected by age, residence, pre-operative visual acuity, presence of diabetes mellitus, and post-operative complications. To improve recovery time of cataract patients, treatment strategies must be prioritized.
Impact of supply chain disruptions and drug shortages on drug utilization: A scoping review protocol
Authors: Santhireswaran Araniy , Ho Martin , Fuller Kaitlin , Gaudette Etienne , Burry Lisa , Tadrous Mina 
Published: November 2024

Objective
This proposed scoping review aims to examine studies assessing the impact of drug shortages on population-level drug utilization trends. The objectives of this review are to a) assess which drugs have been studied and describe associated drug characteristics, b) determine jurisdictions and healthcare settings that have conducted these studies, and c) describe how changes in drug use and the extent of shortage impacts are reported in literature.

Introduction
Drug shortages continue to impair drug access and delivery of quality care across the world. However, the impact of drug supply disruptions on availability and drug use are understudied in current literature. This proposed scoping review will identify this gap and inform future research initiatives aimed at determining the real-world impacts of drug shortages.

Inclusion criteria
Published and unpublished observational studies reporting on the effects of drug supply chain disruptions (shortages, discontinuations, and safety-based withdrawals) on consequent utilization trends faced by pharmaceutical products (i.e. prescription drugs, over-the-counter drugs, vaccines, therapy products, pharmaceutical solutions). Literature reviews, meta-analyses, randomized control trials, case series, case reports, and opinion pieces will be excluded.

Methods
The search strategy will combine two key search concepts: drug shortages and drug utilization. The search will be conducted in MEDLINE and EMBASE. This will be followed by an extensive grey literature search in grey literature databases, targeted websites and Google. Furthermore, reference lists of included articles will be searched. Articles will be independently screened, selected and extracted by two reviewers. Data will be descriptively analyzed and presented in tables.

Trial registration
Review registration number: Open Science Framework, https://osf.io/2p6e5.
Pinworm Infection Misdiagnosed With Primary Eosinophilic Colitis. A Case Series
Authors: Rossi Carlo Maria , Lenti Marco Vincenzo , Lo Bello Antonio , Merli Stefania , Vanoli Alessandro , Anderloni Andrea , Di Sabatino Antonio 
Published: November 2024

ABSTRACT
Parasitic infections make it difficult to establish a diagnosis of primary eosinophilic gastrointestinal disorders (EGID), may even co-occur with inflammatory bowel disease and complicate the management of patients treated with immunosuppressants. Yet, pinworm infection is often ignored as a cause of mucosal eosinophilia. We described 3 cases where pinworm infection was initially misdiagnosed as primary EGID. No current guideline is available for EGID in adult patients, while for patients with inflammatory bowel disease, parasitic infection screening is recommended only in some subset of patients. A more comprehensive and precise recommendation regarding the parasitic species to consider and the diagnostic tests to order is currently lacking.
Situation and perspective on the development of pig and poultry production in the postwar period in Bosnia and Herzegovina
Authors: ADILOVIĆ S. , GAIĆ A. , ADILOVIĆ E. , ŠAKIĆ V. , SMAJLOVIĆ M. 
Published: November 2024

The aggression in Bosnia and Herzegovina destructively effected the animal stock. Before the aggression over 850,000 beef, 1,300,00 sheep, 730,000 pigs, 95,000 horses, 80,000 bee hives and 10.000.000 poultry were being breeded. According to some estimates in Federation of Bosnia and Herzegovina the destroyed animal stock, according to species was 52 to 90 %. One part of the animal stock either remained in the occupied territory or the aggressors sold it in Serbia and Montenegro. Therefore, the results of the aggression, which lasted nearly four years, destroyed parts of the animal stock, especially in the current territory of the Federation of Bosnia and Herzegovina. The renewal of the animal stock started in 1996 when by a Decision from the Coordination Board of the Government of the Federation of Bosnia and Herzegovina a Office for Project Implementation Unit was established (PIU), which enables residents to grow food for their own needs, as well as for the market. By the end of 1997, through this Office, 10,000 calves, 15,000 sheep, 2,000 goats, 200 piglets, a lesser number of poultry and bee hives were distributed. Of the beef the greatest amount was simental 75 %, brown - alpine 10 %, gray-alpine 5 % and Eastern Freesia 10 %. As can be seen, according to the PIU program the least work was done on breeding activities for pigs and poultry and therefore in future more attention will need to be accorded. From that the issue of the renewal of breeding activities of pigs and poultry in the post-war period will be the subject of this paper.
INFLUENCE OF GENOTYPE ON SLAUGHTERING PIG VALUE ACCORDING TO S-EUROP STANDARD
Authors: SENČIĆ Đ. , KRALIK Gordana , ANTUNOVIĆ B. , ANTUNOVIĆ Z. , PETRIČEVIĆ A. , PERKOVIĆ Anica 
Published: November 2024

Slaughtering sides value according to S-EUROP commercial classes was investigated on the example of two pig genetic bases (Swedish Landrace and Line 3). Right pork sides (30 pieces) of analyzed genotypes were dissected by Weniger et al. (1963) method. The sides were sorted into S-EUROP classes according to muscle tissue share and analyzed. The pork sides from different commercial classes within some genotypic bases (Swedish Landrace, Line 3) differ regarding slaughtering quality indicators. Sides from classes with higher meatness have thinner back fat, larger area of MLD cross section, higher ham index, better conformation (higher share of usable and commercially more valuable parts) better muscle tissue distribution and a bit poorer muscle tissue quality. Pork sides of different genetic bases may have different commercial and usable value regarding differences in slaughtering quality and in sides distribution per classes.
STUDY ON BODY FAT CONTENT IN PEKIN, MUSCOVY AND MULE DUCKS
Authors: SZASZ S. , BOGENFÜRST F. 
Published: November 2024

In this study domestic ducks (Pekin type), muscovy and mule ducks were used to determine the body fat content. The fat content of the body in drakes at the age of 7 weeks was 13.8 % in the Pekin type and 14.3 vs. 12.7 % in the muscovy and mule ducks. By the age of 12 weeks this value had increased considerably in the Pekin type, reaching 19.6 %, but had remained stable (12.5 vs. 11.9 %) in the other two types. In the females the Pekin type gained the most in terms of fat content, by the age of 7 weeks exceeding the values observed in the drakes of this type. The mule duck females produced values on nearly the same level as those obtained for the mule drakes, while the results for the muscovy females fell between the values obtained for the mule and the Pekin ducks. By the age of 12 weeks the fat content of the body of the female Pekin ducks was the same as the above time, being on a lower level than that of the drakes of the same type, while the indicators for the mule ducks decreased slightly; the results obtained for the muscovy duck females also decreased to a lower value.
A NOTE ON QUALITY OF CATTLE SLAUGHTERED IN SLOVENIA
Authors: ŽGUR S. , DROBNIČ Marjana 
Published: November 2024

In seven commercial slaughterhouses data were collected from July 1994 to June 1998. Altogether data from 147 888 carcasses were analysed. In young bulls, which represented the most important category, 6 % carcasses were graded into conformation class E and 48 %, 37 %, 8 % and less then 1 % into conformation classes U, R, O and P. More then 97 % of carcasses were graded into fatness classes 2 and 3. In other categories (calves, heifers steers, young and old cows and old bulls) carcasses were most often graded into class R, and into fatness class 3. Carcass weight in all categories exhibited high variability. Carcasses with better conformation grades and higher fatness class also exhibited higher weight.
EVALUATION OF DIETARY VALUE OF HORSE MEAT
Authors: MAKRAY S. , HANCZ C. , STEFLER J. , MARTIN T. G. 
Published: November 2024

The results of this report were derived from a long-term experiment that has been going on since 1988 in the draft horse population at Kaposvár. Seventeen weaning foals representing four genotypes were slaughtered, at the age of 205.2 ± 14.4 days. Final weight was 300.0 ± 45.1 kg, carcass weight was 157.8 ± 27.6 kg, and dressing percentage was 52.9 ± 4.3 %. The results were slightly modified by the small-frame Haflingers, while the other foals were large-frame crossbreds from Hungarian Draft or French dams mated to Percheron or Noriker stallions. The main components: moisture (75.8 ± 1.0 %), protein (20.7 ± 0.9 %), fat (2.3 ± 0.8 %), and ash (0.9 ± 0.3 %) did not differ significantly among breeds. Besides the low total fat content, the low proportion of saturated fatty acids is also a favourable trait of horse meat.
MILK QUALITY ON MERCATOR KMETIJSKO GOSPODARSTVO KOČEVJE FARMS REGARDING EU STANDARDS
Authors: RAJČEVIČ Marija , ŽLINDRA J. , VIDIC A. , POTOČNIK K. 
Published: November 2024

There were analyzed chemical composition and hygienic quality of milk produced in 1996 and 1997 on Mercator Kmetijsko gospodarstvo Kočevje farms. The results for quantity of dry matter without fat, protein, total count of microorganisms (TCMO) and somatic cells count (SCC) were analysed with regard to regulations in Slovenia and compared with requirements in EU (92/46 EEC). As regards mean quantity of dry matter without fat, protein, TCMO and SCC the delivered milk met the EU requirements in both years. There were, however, 25.42 % of milk with less than 85 g of dry matter without fat per kilogram in 1996 and 15.90 % in 1997. There was no milk with less than 28 g of protein per kg. 1.7 % of milk per year did not meet EU requirements since it contained more than 10 x 104/ml TCMO, but according to our regulations (OG RS, 34/98) it can still be redeemed. In 1996, 7.3 % of delivered milk did not meet EU requirements with regard to SCC, and 21.14 % in 1997; in this milk SCC was higher than 40 x 104/ml.
AN INFLUENCE OF CROP DENSITY AND FERTILIZATION ON CORN YIELD AND HIGHER EFFICIENTY IN MILK PRODUCTION
Authors: JURIŠIĆ M. , STJEPANOVIĆ M. , BUKVIĆ Ž. , DOMAČINOVIĆ M. , JURIŠIĆ Ivana 
Published: November 2024

The investigations were carried out at the experimental plot of the Faculty of Agriculture Osijek and Production unit in Vinkovci during 1993 and 1994. Hybrid Bc 592 was used for the investigation. Stands were arranged with space within rows (for S1-48 000 plants ha-1=29.7 cm, S2-60 000 plants ha-1=23.8 cm and S3-80 000 plants ha-1=17.9 cm) and between rows 70 cm.Three nitrogen fertilisations were applied (N1=90, N2=180 and N3=270 kg ha-1) with 100 kg ha-1 P2O5 and 150 kg ha-1 K2O. Foliar treatments by mixture INA-Fertina K1 in 3 % concentration was carried out twice each year in intensive corn growth phase on one part of the experiment. On the basis of corn grain chemical analysis (concentration of main nutritives and water) carried out in 1993 and 1994 it is shown that increased nitrogen fertilisation in the second and third group had positive influence on protein share increase.The highest energy value was achieved in the third group by conversion of different corn yield of some groups into energy value expressed in FU. Namely it was by 723 FU higher than the first group and by 422 FU higher than the second one. This different corn energy value in groups was conversed into amount of one finished animal product-milk as well as its market realisation and the following values were obtained: more milk (by 654 kg i.e.1.572 kg) was produced in the second and third group than in the first group which financially means 1.635 kn i.e.3.929 kn more than the first one. Similar results as with corn in 1993 were achieved by corn conversion of some groups (1994) into energy value.
THE EFFECT OF THE MONITORING OF THE TEMPERATURE OF INCUBATORS AND THE EFFECT OF VARIOUS TEMPERATURES ON THE HATCHABILITY OF GOOSE EGGS
Authors: DANDÉ Krisztina , BOGENFÜRST F. 
Published: November 2024

One of the chief objectives of poultry breeding is to obtain from the total hatching egg yield as many day-old birds as possible which are both viable and suitable for production; thus, hatchability has attained a priority role from the aspect of cost efficiency. Hatching eggs of different sizes have different requirements with respect both to temperature and to humidity. In this experiment three separate incubators were each set at a different temperature, in order to observe the effect of low (37.0o C) and high (39.0o C) temperature on the hatchability of goose eggs and on the intensity of incubation, and also for the purpose of mapping, by means of computer-programmed artificial eggs, changes in temperature in the incubators during the first three days. Computer-programmed artificial eggs were used for the measurement of temperature inside the incubators. The most efficient incubation was observed in the eggs incubated at 37.8o C, although the data obtained for the group incubated at 39.0o C were not substantially less favourable; those incubated at 37.0o C produced the least beneficial incubation results. On the basis of the data obtained it can be ascertained that the goose eggs showed better tolerance of high temperature than of low temperature. Low initial temperature resulted in a high ratio of shell death and protracted incubation. In the remainder of the incubation period the embryos were unable to make up for the shortfall arising in the first three days. The use of the artificial eggs enables incubators to be monitored reliably, both prior to the beginning of incubation and during the incubation period, thus allowing the detrimental effects of inappropriate temperature (too high or too low) to be avoided.
Lamb carcass quality of the “Istrska pramenka” sheep breed
Authors: CIVIDINI Angela , ŽGUR Silvester , KOMPAN Drago , ŽAN Metka 
Published: November 2024

In the experiment described below, the carcass quality of 14 suckling lambs of the autochthonous “Istrska pramenka” breed has analysed. The dams of these lambs were fed on hay ad libidum and 500 g of concentrates per day. Besides suckling, lambs were also fed on 100 g of concentrates containing 20 % of crude protein, per day. At the average age of 55 days they reached a body mass of 19 kg. The dressing percentage was 47. At this age the majority of the lambs were classified as the B-category (64 %), 24 % as the C-category and 14 % as the A-category. 43 % of the lambs were classified as the first quality class. With regard to their insufficient fatness all the lambs were classified as the second quality class. The lambs with a higher carcass mass had darker (lower CIE L-values) and more red (higher CIE a*-values) meat at the cross section of eye muscle (musculus longissimus dorsi).