bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface chemical heterogeneity modulates silica surface hydration
Authors: Schrader Alex M. , Monroe Jacob I. , Sheil Ryan , Dobbs Howard A. , Keller Timothy J. , Li Yuanxin , Jain Sheetal , Shell M. Scott , Israelachvili Jacob N. , Han Songi 
Published: March 2018

SignificanceSilica, conventionally known as “glass,” is a universally used material in catalysis, nanofabrication, and many other applications, but details of its surface chemistry and interactions with water are notoriously complicated and unclear––partially due to its tunable surface chemistry. We utilize this tunable surface chemistry of silica to reveal properties of surface-bound water that impact surface reactions, adhesion, and colloidal interactions. Using a combination of surface forces, hydration dynamics, and simulation techniques, we show that surface silanol groups stabilize the surface water layer, and also that variations/fluctuations are more pronounced at intermediate silanol densities on the surface. This work provides insight into fundamental interactions of water with chemically heterogeneous surfaces.
Category genesis in Chitimacha
Authors: Hieber Daniel W. 
Published: March 2018

Abstract
The genesis of new lexical categories poses a challenge to theories of diachronic change: If there are no pre-existing words in the class to analogize to, how does the category arise? This paper shows that a constructional approach to category change successfully accounts for the genesis of a diverse class of preverbs in Chitimacha, an isolate of the U.S. Southeast linguistic area. It is shown that what enabled the creation of the preverb category was schematization across a variety of forms with similar properties, namely, a preverbal syntactic position and a directional semantics. Category genesis can therefore be viewed as simply a special case of constructionalization wherein schematization plays a crucial role.
Derivation without category change
Authors: Norde Muriel , Morris Caroline 
Published: March 2018

Abstract
Dutch derivational morphology is rich in intensifying prefixoids, i.e. morphemes that occur as independent lexemes but have an intensifying meaning when bound to adjectives or adverbs. A specific variant of these are diminutive prefixoid constructions such as bloedjeserieus (blood-dim-serious) ‘very serious’ or kletsjenat (splash-dim-wet) ‘very wet’. Unlike the regular derivational diminutive however, the diminutive morpheme lacks the ability to change category when added to a prefixoid, and its primary function is a pragmatic one of either emphasis or downtoning. In this paper, we will discuss the formal and semantic-pragmatic properties of the diminutive prefixoid construction, based on an empirical study into its synchronic distribution, as well as explore how prefixoid constructions may be organised in a constructional network.
Why would anyone take long?
Authors: Denison David 
Published: March 2018

Abstract
I review the word classes proposed for long in such idiosyncratic English usages as I won’t be/take long, all night long. Although adverb fits most of the contentious data best, sometimes the word class is underdetermined. I suggest that long exhibits adjective ~ adverb underspecification from Old and Middle English onwards and can also be a semi-grammatical, decategorialised word. We need not assume that every word in every grammatical sentence must belong to one and only one word class (Denison, 2013). At the phrasal level the distribution is less anomalous and correlates with semantic and pragmatic features. Accordingly, it is sensible to describe the history of such usages in Construction Grammar terms. Recent Danish developments make an intriguing comparison.
The emergence of a new adverbial downtoner
Authors: Van Goethem Kristel , Vanderbauwhede Gudrun , De Smet Hendrik 
Published: March 2018

Abstract
The English expression far from, denoting spatial or metaphorical distance, has developed into an adverbial downtoner (De Smet, 2012). In this corpus-based study, our first purpose is to analyze to which degree the Dutch counterparts of the English [far from X] construction, that is [ver van X] and [verre van X], have also developed into downtoners. We show that synchronically ver van mostly has a spatial or metaphorical meaning, while verre van is generally used as an adverbial downtoner. As a second objective, we explore the diachronic pathways taken by both constructions and argue that the category change undergone by [verre van X] is part of a true constructionalization process, while [ver van X] has been affected by minor constructional changes only.
Evaluative morphology in German, Dutch and Swedish
Authors: Battefeld Malte , Leuschner Torsten , Rawoens Gudrun 
Published: March 2018

Abstract
The separation or ‘debonding’ of prefixoids in informal language use in Germanic and the question whether spelling reflects re-categorization of such compound members as adjectives have recently been attracting increased attention among linguists. This contribution focuses on category changes involving lexical items with an evaluative function, both bound (prefixoids, loan prefixes) and unbound (bare nouns), that give rise to defective adjectives in German, Dutch and Swedish. This occurs via two loci of change: the non-head position in nominal and adjectival compounds and the predicative position in sentence constructions. The diverse items serving as ‘evaluatives’ are unified by one abstract schema for ‘evaluative compounds’ across these languages which is paradigmatically related to other, free uses of such items.
Constructional change on the contentful-procedural gradient
Authors: Koutsoukos Nikos 
Published: March 2018

Abstract
This chapter focuses on a rather neglected type of morphological change, that is, the change from derivation to inflection. Contrary to the assumption that derivational patterns usually do not develop any further, this analysis proposes that some derivational constructions may change by acquiring a more functional status, which is characteristic of inflectional categories. Based on the distinction between contentful and procedural constructions, as proposed by Traugott & Trousdale (2013), the emergence of the new constructions can be conceived of as a gradual shift on the contentful-procedural gradient. The argumentation is based on examination of the ‑idz(o) constructions in Griko, a Greek-based dialect spoken in South Italy.
Structure and strength of sub-100 nm lamellar structures in cold-drawn pearlitic steel wire
Authors: Zhang Xiaodan , Hansen Niels , Godfrey Andrew , Huang Xiaoxu 
Published: March 2018

Pearlitic steel wire, with a representative sub-100 nm lamellar structure, is the strongest mass-produced steel with an excellent combination of formability and strength. This overview summarises investigations of cold-drawn pearlitic steel wire in the last decades, covering the microstructural evolution and strengthening mechanisms. Based on quantitative structural parameters, this overview covers a quantitative and extensive analysis of structure–strength relationships. By focusing on the structure, challenges and future strategy are outlined to further improve the mechanical behaviour and performance of pearlitic steel wire to widen its use in society. This is part of a thematic issue on Pearlitic Steel Wires.
Novel effect of α-lactalbumin on the yohimbine-induced hot flush increase of the tail skin temperature in ovariectomized rats
Authors: Uchida Masayuki , Kobayashi Orie 
Published: March 2018

Abstract
5-Hydroxytryptamine (5-HT) and noradrenaline have been thought to play important roles in the mechanism of hot flush. Then, to clarify the relation between serotonergic and adrenergic nervous systems on the mechanism of hot flush, the effect of paroxetine, 5-HT reuptake inhibitor (SSRI) was evaluated on the yohimbine-induced hot flush increase of tail skin temperature in ovariectomized female rats. Yohimbine (adrenaline α2 antagonist) significantly increased the tail skin temperature in course of time. Clonidine (adrenaline α2 agonist) significantly attenuated this effect. Paroxetine also significantly inhibited the increase of tail skin temperature by yohimbine. α-Lactalbumin having SSRI activity in vitro study also significantly inhibited the increase of tail skin temperature, but not significantly decreased the initial temperature. This difference may explain the different mechanism between paroxetine (SSRI) and α-lactalbumin, suggesting new mechanism of hot flush.
Genome Annotation Generator: a simple tool for generating and correcting WGS annotation tables for NCBI submission
Authors: Geib Scott M , Hall Brian , Derego Theodore , Bremer Forest T , Cannoles Kyle , Sim Sheina B 
Published: March 2018

Abstract

Background
One of the most overlooked, yet critical, components of a whole genome sequencing (WGS) project is the submission and curation of the data to a genomic repository, most commonly the National Center for Biotechnology Information (NCBI). While large genome centers or genome groups have developed software tools for post-annotation assembly filtering, annotation, and conversion into the NCBI's annotation table format, these tools typically require back-end setup and connection to an Structured Query Language (SQL) database and/or some knowledge of programming (Perl, Python) to implement. With WGS becoming commonplace, genome sequencing projects are moving away from the genome centers and into the ecology or biology lab, where fewer resources are present to support the process of genome assembly curation. To fill this gap, we developed software to assess, filter, and transfer annotation and convert a draft genome assembly and annotation set into the NCBI annotation table (.tbl) format, facilitating submission to the NCBI Genome Assembly database. This software has no dependencies, is compatible across platforms, and utilizes a simple command to perform a variety of simple and complex post-analysis, pre-NCBI submission WGS project tasks.

Findings
The Genome Annotation Generator is a consistent and user-friendly bioinformatics tool that can be used to generate a .tbl file that is consistent with the NCBI submission pipeline

Conclusions
The Genome Annotation Generator achieves the goal of providing a publicly available tool that will facilitate the submission of annotated genome assemblies to the NCBI. It is useful for any individual researcher or research group that wishes to submit a genome assembly of their study system to the NCBI.
Defective gene expression of the membrane complement inhibitor CD46 in patients with progressive immunoglobulin A nephropathy
Authors: Coppo Rosanna , Peruzzi Licia , Loiacono Elisa , Bergallo Massimilano , Krutova Alexandra , Russo Maria Luisa , Cocchi Enrico , Amore Alessandro , Lundberg Sigrid , Maixnerova Dita , Tesar Vladimir , Perkowska-Ptasińska Agnieszka , Durlik Magdalena , Goumenos Dimitris , Gerolymos Miltiadis , Galesic Kresimir , Toric Luka , Papagianni Aikaterini , Stangou Maria , Mizerska-Wasia Membek Malgorzata , Gesualdo Loreto , Montemurno Eustacchio , Benozzi Luisa , Cusinato Stefano , Hryszko Tomasz , Klinger Marian , Kamińska Dorota , Krajewska Magdalena ,   VALIGA Study Group of the ERA-EDTA Immunonephrology Working Group
Published: March 2018

Abstract

Background
Complement is thought to play a role in immunoglobulin A nephropathy (IgAN), though the activating mechanisms are unknown. This study focused on the gene expression of CD46 and CD55, two key molecules for regulating C3 convertase activity of lectin and alternative complement pathways at a cellular level.

Methods
The transcriptional expression in peripheral white blood cells (WBCs) of CD46 and CD55 was investigated in 157 patients enrolled by the Validation of the Oxford Classification of IgAN group, looking for correlations with clinical and pathology features and estimated glomerular filtration rate (eGFR) modifications from renal biopsy to sampling. Patients had a previous median follow-up of 6.4 (interquartile range 2.8–10.7) years and were divided into progressors and non-progressors according to the median value of their velocity of loss of renal function per year (−0.41 mL/min/1.73 m2/year).

Results
CD46 and CD55 messenger RNA (mRNA) expression in WBCs was not correlated with eGFR values or proteinuria at sampling. CD46 mRNA was significantly correlated with eGFR decline rate as a continuous outcome variable (P = 0.014). A significant difference was found in CD46 gene expression between progressors and non-progressors (P = 0.013). CD46 and CD55 mRNA levels were significantly correlated (P &lt; 0.01), although no difference between progressors and non-progressors was found for CD55 mRNA values. The prediction of progression was increased when CD46 and CD55 mRNA expressions were added to clinical data at renal biopsy (eGFR, proteinuria and mean arterial blood pressure) and Oxford MEST-C (mesangial hypercellularity, endocapillary hypercellularity, segmental glomerulosclerosis, tubular atrophy/interstitial fibrosis, presence of any crescents) score.

Conclusions
Patients with progressive IgAN showed lower expression of mRNA encoding for the complement inhibitory protein CD46, which may implicate a defective regulation of C3 convertase with uncontrolled complement activation.
Data-driven analysis of biomedical literature suggests broad-spectrum benevolence of culinary herbs and spices
Authors: N K Rakhi , Tuwani Rudraksh , Mukherjee Jagriti , Bagler Ganesh 
Published: March 2018

AbstractSpices and herbs are key dietary ingredients used across cultures worldwide. Beyond their use as flavoring and coloring agents, the popularity of these aromatic plant products in culinary preparations has been attributed to their antimicrobial properties. Last few decades have witnessed an exponential growth of biomedical literature investigating the impact of spices and herbs on health, presenting an opportunity to mine for patterns from empirical evidence. Systematic investigation of empirical evidence to enumerate the health consequences of culinary herbs and spices can provide valuable insights into their therapeutic utility. We implemented a text mining protocol to assess the health impact of spices by assimilating, both, their positive and negative effects. We conclude that spices show broad-spectrum benevolence across a range of disease categories in contrast to negative effects that are comparatively narrow-spectrum. We also implement a strategy for disease-specific culinary recommendations of spices based on their therapeutic tradeoff against adverse effects. Further by integrating spice-phytochemical-disease associations, we identify bioactive spice phytochemicals potentially involved in their therapeutic effects. Our study provides a systems perspective on health effects of culinary spices and herbs with applications for dietary recommendations as well as identification of phytochemicals potentially involved in underlying molecular mechanisms.
Bistable emergence of oscillations in structured cell populations
Authors: Martinez-Corral Rosa , Liu Jintao , Suel Gurol , Garcia-Ojalvo Jordi 
Published: March 2018

AbstractBiofilm communities ofBacillus subtilisbacteria have recently been shown to exhibit collective growth-rate oscillations mediated by electrochemical signaling to cope with nutrient starvation. These oscillations emerge once the colony reaches a large enough number of cells. However, it remains unclear whether the amplitude of the oscillations, and thus their effectiveness, builds up over time gradually, or if they can emerge instantly with a non-zero amplitude. Here we address this question by combining microfluidics-based time-lapse microscopy experiments with a minimal theoretical description of the system in the form of a delay-differential equation model. Analytical and numerical methods reveal that oscillations arise through a subcritical Hopf bifurcation, which enables instant high amplitude oscillations. Consequently, the model predicts a bistable regime where an oscillating and a non-oscillating attractor coexist in phase space. We experimentally validate this prediction by showing that oscillations can be triggered by perturbing the media conditions, provided the biofilm size lies within an appropriate range. The model also predicts that the minimum size at which oscillations start decreases with stress, a fact that we also verify experimentally. Taken together, our results show that collective oscillations in cell populations can emerge suddenly with non-zero amplitude via a discontinuous transition.
Democratisation or individualisation? On the distribution of food consumption
Authors: Necula Raluca Alexandra , Mann Stefan 
Published: March 2018

Purpose
While economists are increasingly acknowledging the importance of distributional issues, the distribution of the consumption of food items has largely been neglected. The purpose of this paper is to demonstrate that important insights can be obtained by analysing the distribution of consumption of food products within society.

Design/methodology/approach
This study was conducted by analysing food consumption in two very different countries: Romania, a middle-income country and Switzerland, one of the most prosperous countries in the world. In order to test the formulated hypotheses, consumption per capita was calculated, as a base for the calculation of the Gini coefficient of consumption for each product. A mixed effect model was applied for total food and for meat, computing the predictors for the variable “consumption distribution”.

Findings
Using the Gini coefficients of food and drink item consumption by Romanian and Swiss households, the authors tested the hypothesis that in prosperous middle-income countries the homogeneity of food consumption is growing over time as a sign of consumption democratisation, whereas in high-income countries a growing degree of individualisation is leading to decreasing homogeneity. For meat, the bifurcation of consumption patterns between vegetarians and hedonists leads to a growing Gini coefficient over time for both countries. The analysis controls for factors such as the products’ importance in the diet and their price.

Originality/value
The paper approaches a new subject and raises a new research question that may be relevant for structural issues of contemporary society. Both the comparative analysis of food distribution in two different societies and their dynamics is a novelty.
Pilot study on food sharing and social media in Italy
Authors: D’Ambrosi Lucia 
Published: March 2018

Purpose
The purpose of this paper is to gauge consumer attitudes to food sharing practices in Italy and to assess the support that digital technologies can offer in to promote more responsible consumption.

Design/methodology/approach
The methodology involves a web-based survey through using specialized online platforms (e.g. websites; Facebook groups; and Facebook pages), which provide content on sustainable and responsible consumption and crowd funding campaigns.

Findings
The research highlights the increasingly aware and attentive consumer attitudes towards collaborative economic practices compared to the past. In Italy, however, digital platforms for exchanging surplus food or goods are still poorly used. In fact, there is still a lack of knowledge, largely conditioned by recent experienced with some apps and by the poor development of this type of market.

Research limitations/implications
The research is a pilot of a small-scale study protocol conducted in January 2017 to ascertain the suitability of a wider project on social food sharing practices and environmental sustainability, by determining its feasibility or obtaining information for identification of the key indicators and analysis of the dimensions of the final study.

Originality/value
The research produces first empirical results that may provide new information, related to the role of digital media, on consumption habits.
Perceived quality and intention to revisit coffee concept shops in Malaysia
Authors: Ting Hiram , Lau Wee Ming , Cheah Jun-Hwa , Yacob Yusman , Memon Mumtaz Ali , Lau Evan 
Published: March 2018

Purpose
The purpose of this paper is to examine the effect of perceived quality on intention to revisit coffee concept shops among regular and irregular consumers. Specifically, the framework developed by Pine and Gilmore (2000) is adopted to look into the effect of product, service and experience qualities on intention to revisit.

Design/methodology/approach
The explanatory sequential mixed-methods design was used to articulate the intention of consumers to revisit coffee concept shops. A preliminary study was conducted to define regular and irregular consumers. Self-administered questionnaire was first administered before using interview to elicit more insights and triangulate the findings.

Findings
The combination of both quantitative and qualitative findings show that the experiences of regular consumers at coffee concept shops include personal routine activities, while the experiences of irregular customers are composed of occasions with specific and collective purposes. While the intention to revisit of the former is related to the product and service quality, the intention of the latter is largely affected by its service and experience quality.

Originality/value
Given the rapid rise of coffee concept shops in the developing markets, the use of a mixed-methods design provides more insights into the intention to revisit of the regular and irregular consumers. It underscores the importance for the organisations to know what really matters to the diverse consumers.
Exploring loyalty to specialty foods among tourists and residents
Authors: Suhartanto Dwi , Chen Brendan T. , Mohi Zurinawati , Sosianika Adila 
Published: March 2018

PurposeThe purpose of this paper is to examine a specialty food loyalty model which includes perceived quality, satisfaction, and motivation, and to assess the model’s applicability in two distinct groups of customers: tourists and residents.Design/methodology/approachData were collected from 455 specialty food customers in Bandung, Indonesia. Variance-based structural equation modeling (partial least squares (PLS)) was used to examine the relationship between the drivers (perceived quality, satisfaction and motivation) and loyalty according to the data presented by tourists and residents.FindingsThis study indicates that the perception of quality is an important factor affecting tourists’ and residents’ satisfaction with, and loyalty to, a product. Furthermore, this study suggests that motivation factors are important for tourists and residents in regard to developing loyalty to specialty foods.Practical implicationsThis study provides a venue for retail managers and producers to improve their business performance by developing specialty foods of high quality. To improve their quality, this research suggests that managers and retailers focus on innovation based on exotic and unique traditional food reflecting the richness of local culture. To ensure their loyalty, customers of specialty foods need to be motivated by internal and external factors.Originality/valueThis study is one of the first to examine the formation of specialty food loyalty in two distinct groups of customers: tourists and residents.