bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oestrogen receptor Rsa I gene polymorphism in osteoporosis periodontitis patients with or without dental fluorosis
Authors: Priyanka Dalvi , Vandana Kharidi Laxman 
Published: June 2019

Background & objectives:
There is a paucity of information on association between dental fluorosis, osteoporosis and periodontitis. The aim of this pilot study was to evaluate oestrogen receptor (ER) Rsa 1 gene polymorphism in osteoporosis periodontitis patients with and without dental fluorosis.

Methods:
Twenty one primary osteoporotic patients suffering from periodontitis with dental fluorosis and 20 primary osteoporotic patients suffering from periodontitis without dental fluorosis participated in this study. Periodontitis was diagnosed based on age, gender T-scores using clinical parameters such as plaque scores, gingival bleeding scores and probing pocket depth, clinical attachment level (CAL) and severity of dental fluorosis. DNA was genotyped at the RsaI RFLP (in exon 5) inside the ER gene to study ER Rsa I gene polymorphism in osteoporosis periodontitis patients with and without dental fluorosis.

Results:
Patients with dental fluorosis had higher degree of osteoporosis than those without fluorosis. CAL was significantly higher (P<0.05) in those with dental fluorosis compared with those without. Rr heterozygote (21.95%) was observed in patients without fluorosis whereas RR mutant homozygote was absent in both the groups. Rr wild homozygote type was seen more in the patients with fluorosis (51.21%). Significant differences were found in distribution of these genotypes between patients with and without dental fluorosis.

Interpretation & conclusions:
This preliminary study showed the presence of ER I gene polymorphism in osteoporosis periodontitis patients without dental fluorosis. Further studies with large sample size are needed to confirm the association shown in this preliminary study.
Impact of tuberculosis on glycaemic status
Authors: Krishnappa Darshan , Sharma Surendra K. , Singh Achintya Dinesh , Sinha Sanjeev , Ammini A.C. , Soneja Manish 
Published: June 2019

Background & objectives:
Diabetes mellitus (DM) is an important risk factor for tuberculosis and has received increasing emphasis. However, the reverse association of tuberculosis impacting blood sugar levels has not been well studied. The present study was conducted to evaluate the prevalence of hyperglycemia in patients with tuberculosis and assess its resolution following successful treatment of tuberculosis.

Methods:
In this prospective study, a total of 582 patients with tuberculosis were evaluated for hyperglycaemia [DM or impaired glucose tolerance (IGT)] with random blood sugar (RBS) and all patients with RBS >100 mg/dl were subjected to a 75 g oral glucose tolerance test (OGTT). All patients received thrice weekly intermittent Directly Observed Treatment Short Course (DOTS) for tuberculosis. Patients with hyperglycaemia were re-evaluated at the end of anti-tuberculosis treatment with an OGTT and glycated hemoglobin (HbA1c) levels to assess for glycaemic status.

Results:
In the present study, 41 of the 582 patients were found to have DM [7%, 95% confidence interval (CI) (5.2, 9.4)] while 26 patients were found to have IGT [4.5%, 95% CI (3, 6.5)]. Three patients were lost to follow up. Of the 26 patients with IGT, 17 [65.4%, 95% CI (46.1, 80.7)] reverted to euglycaemic status following successful treatment of tuberculosis, while the blood sugar levels improved in all patients with DM following treatment of tuberculosis.

Interpretation & conclusions:
Our study results show that tuberculosis adversely impacts glycaemic status with improvement in blood sugar levels at the end of successful treatment of tuberculosis. Longitudinal studies with large sample size are required to confirm these findings.
Infinitesimal Hilbertianity of Weighted Riemannian Manifolds
Authors: Lučić Danka , Pasqualetto Enrico 
Published: June 2019

AbstractThe main result of this paper is the following: anyweightedRiemannian manifold$(M,g,\unicode[STIX]{x1D707})$,i.e., a Riemannian manifold$(M,g)$endowed with a generic non-negative Radon measure$\unicode[STIX]{x1D707}$, isinfinitesimally Hilbertian, which means that its associated Sobolev space$W^{1,2}(M,g,\unicode[STIX]{x1D707})$is a Hilbert space.We actually prove a stronger result: the abstract tangent module (à la Gigli) associated with any weighted reversible Finsler manifold$(M,F,\unicode[STIX]{x1D707})$can be isometrically embedded into the space of all measurable sections of the tangent bundle of$M$that are$2$-integrable with respect to$\unicode[STIX]{x1D707}$.By following the same approach, we also prove that all weighted (sub-Riemannian) Carnot groups are infinitesimally Hilbertian.
Block Decomposition and Weighted Hausdorff Content
Authors: Saito Hiroki , Tanaka Hitoshi , Watanabe Toshikazu 
Published: June 2019

AbstractBlock decomposition of$L^{p}$spaces with weighted Hausdorff content is established for$0<p\leqslant 1$and the Fefferman–Stein type inequalities are shown for fractional integral operators and some variants of maximal operators.
The Agromorphological characterization of the perfume rose (Rosa damascena Mill.) Of Kelâa M'gouna-Dades (Morocco).
Authors: Aithida Amal , Tahiri Abdelghani , Oubassine Youssef , Cherifi Kalil , Mokhtari Mimoun , Hassani Lalla Amina Idrissi 
Published: June 2019

Rosa damascena perfume rose has a considerable place in Morocco. The essential oil, hydrolate (rose water) and dried buds produced in Kalâa Mgouna are intended for export. However, local varieties are not identified. Hence, the objective of our research into the identification of morphological variability by studying 15 qualitative and quantitative characteristics related to leaf, spine and flower at eight localities along the valley of roses.
The present study has demonstrated the existence of a great morphological variability within the Kalâa Mgouna’s perfume rose. The characters associated with leaves and spines drive this variability. The PCA analysis identified four morphotypes; the morphotype I whose stems are unarmed, the morphotype II characterized by broad leaves and moderately spiny stems, the morphotype III having stems bearing long spines and whose petals are wider. Finally, the morphotype IV characterized by very thorny stems, leaves of reduced size and whose petals are wider.
Emission inventory of semi-volatile and intermediate-volatility organic compounds and their effects on secondary organic aerosol over the Pearl River Delta region
Authors: Wu Liqing , Wang Xuemei , Lu Sihua , Shao Min , Ling Zhenhao 
Published: June 2019

Abstract. Semi-volatile and intermediate-volatility organic
compounds (S–IVOCs) are considered critical precursors of secondary
organic aerosol (SOA), which is an important component of fine particulate
matter (PM2.5). However, knowledge of the contributions of S–IVOCs
to SOA is still lacking in the Pearl River Delta (PRD) region,
southern China. Therefore, in this study, an emission inventory of S–IVOCs
in the PRD region was developed for the first time for the year 2010. The
S–IVOC emissions were calculated based on a parameterization method involving
the emission factors of POA (primary organic aerosol), emission ratios of
S–IVOCs to POA, and domestic activity data. The total emissions of S–IVOCs
were estimated to be 323.4 Gg, with major emissions from central cities in the
PRD, i.e., Guangzhou, Foshan, and Shenzhen. On-road mobile sources and
industries were the two major contributors of S–IVOC emissions, with
contributions of ∼42 % and ∼35 %,
respectively. Furthermore, uncertainties of the emission inventory were
evaluated through Monte Carlo simulation. The uncertainties ranged from
−79 % to 229 %, which could be mainly attributed to mass fractions of OC
(organic carbon) to PM2.5 from on-road mobile emissions and emission
ratios of IVOCs ∕ POA. The developed S–IVOC emission inventory was further
incorporated into the Weather Research and Forecasting with Chemistry
(WRF-Chem) model with a volatility basis-set (VBS) approach to improve the
performance of SOA simulation and to evaluate the influence of S–IVOCs on
SOA formation at a receptor site (Wan Qing Sha (WQS) site) in the PRD. The
following results could be obtained. (1) The model could resolve about
34 % on average of observed SOA concentrations at WQS after considering
the emissions of S–IVOCs, and 18 %–77 % with the uncertainties of the
S–IVOC emission inventory considered. (2) The simulated SOA over the PRD
region was increased by 161 % with the input of S–IVOC emissions, and it
could be decreased to 126 % after the reaction coefficient of S–IVOCs with
OH radical was improved. (3) Among all anthropogenic sources of S–IVOCs,
industrial emission was the most significant contributor of S–IVOCs for SOA
formation, followed by on-road mobile, dust, biomass burning, residential,
and off-road mobile emissions. Overall, this study firstly quantified
emissions of S–IVOCs and evaluated their roles in SOA formation over the PRD,
which contributes towards significantly improving SOA simulation and better
understanding of SOA formation mechanisms in the PRD and other regions in China.
Evaluation of Clinical Outcomes in Hospitalized Patients With Exertional Rhabdomyolysis
Authors: Arnautovic Jelena Z. , Tereziu Stela 
Published: June 2019

AbstractContextExertional rhabdomyolysis (ER) is a medical condition in which excessive and unaccustomed physical activity results in skeletal muscle damage in otherwise healthy individuals.ObjectiveTo assess the overall outcomes of patients who presented to the emergency department with ER.MethodsThis retrospective study was conducted across 4 hospitals. The study included nonpregnant adults with no history of renal function impairment or myopathy disorder who had a diagnosis of ER in the emergency department setting. Medical records were reviewed for patient demographics, length of stay, complications, mechanism(s) of injury involved, impact of nutritional supplements, spectrum of creatine kinase (CK) responses, prevalence of hospital readmissions, and overall mortality.ResultsOf the 800 rhabdomyolysis cases identified during the 24-month study period, 41 were included in the study. The mean age was 29 years, and the patients were predominantly male (33 [80.5%]) and white (25 [61%]). The median length of stay was 2 days, and it correlated significantly with initial and peak CK levels (R=0.45,P=.004, andR=0.52,P<.001, respectively). Median initial and peak CK were noted to be 16,888 (range, 342-194,403) U/L and 18,534 (range, 342-287,565) U/L, respectively. Median discharge CK was 5287 (range, 10-61,617) U/L. The most commonly cited mechanism of injury was weight lifting (16 [39%]). In terms of overall outcomes, transient kidney injury was noted in 3 cases (7.4%), and no mortality was recorded during the admission or at 12 months of follow-up. Compartment syndrome or severe electrolyte abnormalities were not observed. There were only 2 uncomplicated readmissions (4.8%) due to high-intensity interval training.ConclusionHospitalized patients with ER without a history of renal impairment tend to have relatively low risks of complications and readmission.
Conceptual Framework to Evaluate Health Care Professionals’ Satisfaction in Utilizing Telemedicine
Authors: Law Timothy , Cronin Cory , Schuller Kristin , Jing Xia , Bolon Douglas , Phillips Brian 
Published: June 2019

Abstract

Context
Several advantages of telemedicine have been reported, such as improved patient satisfaction, reduced costs, and broader access to specialists. However, most studies have focused on patient satisfaction with telemedicine services. A literature gap exists in evaluating health care professionals’ (both referring and performing professionals) satisfaction in delivering telemedicine services. A clear picture of professionals' telemedicine satisfaction has the potential to improve care quality, care accessibility, and telemedicine adoption and to reduce overall health care costs.

Objectives
To develop a framework to evaluate health care professionals’ satisfaction in delivering telemedicine services and to articulate the factors that can contribute to their satisfaction.

Methods
We developed an initial conceptual framework based on existing literature and the research team's expertise. The initial framework was validated by a convenience group of 12 osteopathic and allopathic physicians, and the framework was further revised and refined according to their input.

Results
The refined framework includes 5 main components (professionals’ demographics, care settings, motivations, experiences, and overall satisfaction) that can contribute to health care professionals' satisfaction or dissatisfaction in delivering telemedicine services. Detailed itemization is provided under each component, including hierarchical organizations of the items, definitions, and potential value sets.

Conclusions
The refined conceptual framework may provide a comprehensive evaluation reference for measuring professionals’ satisfaction in delivering telemedicine. Further customization according to the specific setting of telemedicine services is needed. This refined conceptual framework can also be used to identify areas that can be improved and to ultimately improve telemedicine services and care quality.
Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Emerging Osteopathic Approach: A Narrative Review
Authors: Larrimore Christopher , Ramnot Amanda , Jaghab Annmarie , Sarduy Sofia , Guerrero George , Troccoli Peter , Hilton Kelly , Bested Alison 
Published: June 2019

AbstractMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating syndrome of unknown origin, characterized by profound postexertional malaise and fatigue, unrefreshing sleep, cognitive impairments, immune dysfunction, pain, autonomic dysfunction, and neuroendocrine symptoms. Although ME/CFS is well documented within the medical literature, it remains difficult to diagnosis and manage. Some of the current challenges include an absence of diagnostic markers, differing diagnostic criteria, and an overall lack of awareness within the medical community. As a result, patients are often frustrated by the difficulties in acquiring a diagnosis and from the overall lack of available treatments. In an effort to increase awareness, this review discusses disease pathophysiology, clinical presentation, and treatment options, while also highlighting the benefits of an osteopathic approach.
Suction Decompression of the Carpal Tunnel
Authors: Sucher Benjamin M. 
Published: June 2019

Abstract
Carpal tunnel syndrome (CTS) is a common nerve compression syndrome that includes symptoms of numbness and tingling in the median nerve distribution. Medical cupping therapy has been used for managing a variety of medical conditions, but, to the author's knowledge, the cupping device has not been directly applied over the carpal tunnel as a form of treatment. This case report involves a 27-year-old woman who presented with symptoms of CTS in the right hand and palpatory restriction over the right carpal canal. Electrodiagnostic testing confirmed mild CTS, and neuromuscular ultrasonography revealed a mildly enlarged median nerve at the wrist, which was also consistent with CTS. The patient was taught to use a cupping device that would allow her to apply suction over the ventral wrist daily. The patient noted improvement over several weeks and was asymptomatic at her 3-month follow-up visit. Repeated testing revealed that initial abnormalities in the wrist had resolved. Suction decompression of the carpal tunnel may be a viable alternative treatment for patients with mild CTS.
Indicadores de desempenho e engajamento profissional em organizações inovadoras
Authors: Santos Marília Maria de Oliveira , Quel Luiz Felipe , Vieira Almir Martins , Rosini Alessandro Marco 
Published: June 2019

O presente estudo tem como objetivo analisar a inclusão do índice de engajamento profissional dentre os indicadores do Balanced Scorecard [BSC], particularmente na perspectiva Aprendizagem e Crescimento. A abordagem metodológica tem natureza exploratória e caráter quantitativo, sendo a pesquisa realizada com a participação de 185 gestores de organizações que estão listadas como inovadoras e não inovadoras. O instrumento utilizado foi o Ultrech Work Engagement Scale [UWES], que mede os níveis do engajamento. O resultado revelou que engajamento profissional pode agregar valor aos indicadores de desempenho estratégico nas organizações inovadoras. Conclui-se que a prática de desenvolvimento de pessoas, que está inserida na perspectiva de Aprendizagem e Crescimento do BSC, adicionada ao indicador de engajamento profissional, traz resultados positivos para as organizações, criando um clima propício para que os funcionários se sintam mais engajado sem suas tarefas, mais interessados e inseridos em um ambiente que lhes traga mais confiança e bem-estar.
Robust adaptive steering control for unmanned surface vehicle with unknown control direction and input saturation
Authors: Wang Shasha , Fu Mingyu , Wang Yuanhui 
Published: June 2019

SummaryA robust adaptive steering control method is proposed to solve the control problem of the unmanned surface vehicle (USV) with uncertainties, unknown control direction, and input saturation. In the controller design process, the adaptive fuzzy system is incorporated into dynamic surface control (DSC) to approximate the uncertainty term induced by external environmental disturbances and model parameters. Then, the Nussbaum function is used to eliminate the requirement for a priori knowledge of the control direction. Besides, to handle the input saturation, the adaptive fuzzy DSC is extended by a second‐order nonlinear filter and antisaturation auxiliary function to compensate for the magnitude and rate saturation of the rudder. All signals of the closed‐loop system are proven to be uniformly ultimately bounded (UUB) by Lyapunov theorem and the Lemma of Nussbaum gain, and the course error can converge to a small neighborhood of zero through choosing design parameters appropriately. Finally, simulation results and comprehensive comparisons are shown for the USV course system, which is demonstrative of the proposed controller's effectiveness and robustness.
Mass Production of High‐Quality Transition Metal Dichalcogenides Nanosheets via a Molten Salt Method
Authors: Jin Hongrun , Hu Zhimi , Li Tianqi , Huang Liang , Wan Jun , Xue Guobin , Zhou Jun 
Published: June 2019

Abstract2D transition metal dichalcogenides (TMDs) are well suited for energy storage and field–effect transistors because of their thickness‐dependent chemical and physical properties. However, as current synthetic methods for 2D TMDs cannot integrate both advantages of liquid‐phase syntheses (i.e., massive production and homogeneity) and chemical vapor deposition (i.e., high quality and large lateral size), it still remains a great challenge for mass production of high‐quality 2D TMDs. Here, a molten salt method to massively synthesize various high‐crystalline TMDs nanosheets (MoS2, WS2, MoSe2, and WSe2) with the thicknesses less than 5 nm is reported, with the production yield over 68% with the reaction time of only several minutes. Additionally, the thickness and size of the as‐synthesized nanosheets can be readily controlled through adjusting reaction time and temperature. The as‐synthesized MoSe2 nanosheets exhibit good electrochemical performance as pseudocapacitive materials. It is further anticipates that this work will provide a promising strategy for rapid mass production of high‐quality nonoxides nanosheets for energy‐related applications and beyond.
Infrared Glass–Ceramics with Multidispersion and Gradient Refractive Index Attributes
Authors: Sisken Laura , Kang Myungkoo , Veras Johann M. , Lonergan Charmayne , Buff Andrew , Yadav Anupama , McClane Devon , Blanco Cesar , Rivero‐Baleine Clara , Mayer Theresa S. , Richardson Kathleen A. 
Published: June 2019

AbstractInfrared (IR) glass–ceramics (GCs) hold the potential to dramatically expand the range of optical material solutions available for use in bulk and planar optical systems in the IR. Current material solutions are limited to single‐ or polycrystalline materials and traditional IR‐transparent optical glasses. GCs that can be processed with spatial control and extent of induced crystallization present the opportunity to realize an effective refractive index variation, enabling arbitrary gradient refractive index elements with tailored optical function. This work discusses the role of the parent glass composition and morphology on nanocrystal phase formation in a multicomponent chalcogenide glass. Through a two‐step heat treatment protocol, a Ge–As–Pb–Se glass is converted to an optical nanocomposite where the type, volume fraction, and refractive index of the precipitated crystalline phase(s) define the resulting nanocomposite's optical properties. This modification results in a giant variation in infrared Abbe number, the magnitude of which can be tuned with control of crystal phase formation. The impact of these attributes on the GCs' refractive index, transmission, dispersion, and thermo‐optic coefficient is discussed. A systematic protocol for engineering homogeneous or gradient changes in optical function is presented and validated through experimental demonstration employing this understanding.
Insights into Structural Evolution of Lithium Peroxides with Reduced Charge Overpotential in Li−O2 System
Authors: Tan Guoqiang , Chong Lina , Zhan Chun , Wen Jianguo , Ma Lu , Yuan Yifei , Zeng Xiaoqiao , Guo Fangmin , Pearson John E. , Li Tao , Wu Tianpin , Liu Di‐Jia , Shahbazian‐Yassar Reza , Lu Jun , Liu Cong , Amine Khalil 
Published: June 2019

AbstractReducing charge–discharge overpotential is of great significance to enhance the efficiency and cyclability of Li−O2 batteries. Here a dramatically reduced charge overpotential (0.4 V) via a rational design of cathode architecture, which features highly uniform Pt and Pt3Co nanocrystals embedding within nitrogen‐doped cobalt@graphene heterostructures is successfully achieved. Because of the improvement in the catalytic efficiency for optimizing the electrical and dynamic properties, the cathode design enables promising electrochemical performance. More importantly, the results reveal different overpotentials prompted by different structural evolution of bulk Li2O2, which largely depends on the Pt modification approach (surface‐coating and bulk‐doping). This dependence is found to be attributed to the influence of Pt nanocomponents and their dispersion on the formation and decomposition mechanism of Li2O2. Density functional theory calculations provide mechanistic insights into the promotional effect of Pt and Pt3Co on the reduction of the charge overpotential. Finally, an inner relationship between overpotential and electrochemical kinetics is proposed.