bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversidad y vulnerabilidad de la flora orquideológica de un bosque montano nuboso del Valle Central de Costa Rica
Authors: Cascante-Marín Alfredo , Trejos Hernández Christian 
Published: April 2019

Los Cerros de La Carpintera son una formación montañosa en el Valle Central de Costa Rica que alberga remanentes de bosque nuboso en sus partes altas y están rodeados por áreas urbanas y agrícolas. Con el interés de promover su conservación, este trabajo documenta la diversidad de su flora orquideológica e identifica especies vulnerables a la extinción utilizando como criterio la distribución geográfica latitudinal y por elevación. El área de estudio comprendió 742 ha localizadas en las partes altas de los cerros (1600–1850 m) las cuales reciben la mayor influencia de la nubosidad. Se documentaron 136 especies en 52 géneros, aumentando en 74% la diversidad de orquídeas con respecto al listado más reciente para la zona. Los géneros Epidendrum (22 spp.) y Stelis (14 spp.) fueron los más diversos, pero la mayoría de ellos (62%) estuvieron representados por una sola especie. El hábito epífito fue dominante (91%). Se identificaron 30 especies como vulnerables a extinción debido a su distribución restringida, ya sean endémicas nacionales o de bosques montanos altos (sobre 1500 m). Sumando las especies amenazadas por extracción ilegal y aquellas especies raras no recolectadas en los últimos 80 años la cantidad de especies vulnerables aumenta a 40 especies (29% del total). Los Cerros de La Carpintera son un reservorio importante para la conservación in-situ de orquídeas a nivel nacional. Utilizando las orquídeas como modelo, estudios demográficos y reproductivos a mediano plazo podrían brindar indicios del efecto del cambio climático sobre las plantas epífitas de los bosques montanos nubosos.
Palabras clave: Cerros de La Carpintera, conservación, distribución geográfica, endemismo, epífitas, Orchidaceae
Podocyte-Specific Sialylation-Deficient Mice Serve as a Model for Human FSGS
Authors: Niculovic Kristina M. , Blume Linda , Wedekind Henri , Kats Elina , Albers Iris , Groos Stephanie , Abeln Markus , Schmitz Jessica , Beuke Esther , Bräsen Jan H. , Melk Anette , Schiffer Mario , Weinhold Birgit , Münster-Kühnel Anja K. 
Published: April 2019

Significance Statement
Although glycosylation of the endothelial surface layer is known to be crucial for kidney function, the role of podocyte glycosylation is not well understood. The authors demonstrated that podocyte-specific ablation of sialylation in mice caused a phenotype resembling human FSGS. Loss of sialylation resulted in disturbance of podocyte homeostasis and podocyte loss in vivo. In vitro, sialylation-deficient podocytes were able to proliferate and differentiate, but did not grow out of isolated glomeruli; they also showed impaired adhesion to collagen, suggesting a crucial role of sialylation for podocyte interaction with the glomerular basement membrane. These findings strongly implicate sialylation as a factor in FSGS pathogenesis, and it therefore might serve as both a diagnostic marker and a therapeutic target to delay disease progression.

Background
The etiology of steroid-resistant nephrotic syndrome, which manifests as FSGS, is not completely understood. Aberrant glycosylation is an often underestimated factor for pathologic processes, and structural changes in the glomerular endothelial glycocalyx have been correlated with models of nephrotic syndrome. Glycans are frequently capped by sialic acid (Sia), and sialylation’s crucial role for kidney function is well known. Human podocytes are highly sialylated; however, sialylation’s role in podocyte homeostasis remains unclear.

Methods
We generated a podocyte-specific sialylation-deficient mouse model (PCmas−/−
) by targeting CMP-Sia synthetase, and used histologic and ultrastructural analysis to decipher the phenotype. We applied CRISPR/Cas9 technology to generate immortalized sialylation-deficient podocytes (asialo-podocytes) for functional studies.

Results
Progressive loss of sialylation in PCmas−/−
mice resulted in onset of proteinuria around postnatal day 28, accompanied by foot process effacement and loss of slit diaphragms. Podocyte injury led to severe glomerular defects, including expanded capillary lumen, mesangial hypercellularity, synechiae formation, and podocyte loss. In vivo, loss of sialylation resulted in mislocalization of slit diaphragm components, whereas podocalyxin localization was preserved. In vitro, asialo-podocytes were viable, able to proliferate and differentiate, but showed impaired adhesion to collagen IV.

Conclusions
Loss of cell-surface sialylation in mice resulted in disturbance of podocyte homeostasis and FSGS development. Impaired podocyte adhesion to the glomerular basement membrane most likely contributed to disease development. Our data support the notion that loss of sialylation might be part of the complex process causing FSGS. Sialylation, such as through a Sia supplementation therapy, might provide a new therapeutic strategy to cure or delay FSGS and potentially other glomerulopathies.
THE DEVELOPMENT OF INDONESIAN NATIONAL QUALIFICATIONS FRAMEWORK (INQF) - BASED ELECTRICAL AND ELECTRONIC SUBJECT AT VOCATIONAL HIGH SCHOOL KAL-1 SURABAYA
Authors: Setyo Budi Karno , Muslim Supari 
Published: April 2019

Purpose of Study: Ineffective implementation of curriculum 2013 and low quality of vocational school graduates underlay the present study. The Presidential Regulation of the Republic of Indonesian number 8 year 2012 stipulates that the implementation of Indonesian National Curriculum Framework-based on curriculum 2013 will improve the quality of vocational high school graduates at level 2 and their learning outcomes, including cognitive, affective, and psychomotor domains. The development of the Indonesian National Curriculum framework-based curriculum 2013 was an activity in generating an educational curriculum at an institutional level which aligns the needs of business and industry.
The design of this study was the 4-D models of Thiagarajan, namely 1) the definition; 2) design; 3) development; and 4) deployment, but this was only conducted up to the development stage.
Methodology: Regarding the background, the research questions were formulated as follows: (1) how is the validity, practicality, and effectiveness of the instructional design of the Basic Electrical and Electronic subject?; (2) how is the students’ response to the instructional design of the Basic Electrical and Electronic Subject?; and (3) how are the results of students’ learning outcomes of Basic Electrical and Electronic Subject?.
Results: This study aimed to find out: (1) the level of validity, practicality, and effectiveness of the instructional design of the Basic Electrical and Electronic Subject; (2) the students’ response of the instructional design of the Basic Electrical and Electronic Subject; and (3) the students’ learning outcomes of the Basic Electrical and Electronic Subject.
Implications/Applications: The conclusion of this research is: 1) the average score on the validity of the instructional design was 3.722 (very high), the average score on its feasibility was 3.72 (very practical), while the average score of its effectiveness was 71.87 (effective); 2) the students’ responses to the instructional design were 92%, which was satisfactory; and 3) the average score of the students’ learning results was 85, over the minimum score determined, with the learning mastery of 100%.
ИССЛЕДОВАНИЕ РАБОТЫ НИЗКОВОЛЬТНОГО УДАРНОГО ГЕНЕРАТОРА В УСТРОЙСТВЕ ЭЛЕКТРОГИДРАВЛИЧЕСКОГО ВОЗДЕЙСТВИЯ ДЛЯ МАЛОГЛУБИННОЙ СЕЙСМОРАЗВЕДКИ
Authors: (Sergey V. Pustynnikov) Пустынников Сергей Владимирович , (Gennady V. Nosov) Носов Геннадий Васильевич , (Wei Han) Хан Вей , (Mariya G. Nosova) Носова Мария Геннадьевна 
Published: April 2019

Актуальность исследования обусловлена необходимостью разработки новых источников мощных импульсов тока для работы на электрогидравлический излучатель с раздвигающимися электродами, который может применяться для возбуждения сейсмических волн в невзрывной сейсморазведке. Цель: провести расчетные и экспериментальные исследования работы низковольтного ударного генератора на дугу в воде, инициированную раздвигающимися электродами в режиме одиночных импульсов и при получении серии импульсов давления. Провести оптимизацию параметров ударного генератора и электрогидравлического излучателя с целью получения максимального импульса давления. Объекты: низковольтный ударный генератор, выполненный в габаритах кранового асинхронного двигателя МТН-612, подключенный к электрогидравлическому излучателю с раздвигающимися электродами. Методы: согласование параметров ударного генератора и дугового разряда методом планирования эксперимента с помощью математической модели. Результаты. Проведены лабораторные исследования работы низковольтного ударного генератора на дугу в воде, инициированную раздвигающимися электродами в режиме одиночных импульсов и при получении серии импульсов. Методом планирования эксперимента получена математическая модель работы ударного генератора на дугу в воде, инициированную раздвигающимися электродами в режиме одиночных импульсов, получены уравнения регрессии для выходных параметров дугового разряда, проведена оптимизация параметров ударного генератора и электрогидравлического излучателя, что позволяет получить максимальный импульс давления для проведения малоглубинной сейсморазведки. Полученный амплитудно-частотный спектр импульса давления показал, что основная энергия импульса давления лежит в среднечастотном диапазоне от 50 до 100 Гц, что обеспечивает высокий сейсмический КПД для проведения малоглубинной сейсморазведки.
ИНДИКАТОРЫ ЯДЕРНОГО ТЕХНОГЕНЕЗА НА ПРИМЕРЕ ТЕРРИТОРИИ, ПРИЛЕГАЮЩЕЙ К БЫВШЕМУ СЕМИПАЛАТИНСКОМУ ИСПЫТАТЕЛЬНОМУ ПОЛИГОНУ
Authors: (Merey T. Jambayev) Джамбаев Мерей Тлеуканович , (Natalia V. Baranovskaya) Барановская Наталья Владимировна , (Aleksandra V. Lipikhina) Липихина Александра Викторовна , (Vladislav V. Boev) Боев Владислав Викторович , (Madina K. Raiymkulova) Райымкулова Мадина Кумарбеккызы , (Zukhra S. Apsalikova) Апсаликова Зухра Сансызбаевна , (Alexander F. Sudyko) Судыко Александр Федорович 
Published: April 2019

Актуальность исследования определяется необходимостью выявления индикаторных свойств химического состава компонентов природной среды, локальных и региональных особенностей их состава с учетом природных и антропогенных факторов воздействия в целях проведения экологической оценки и районирования на территориях, испытывающих специфическое воздействие объектов ядерного техногенеза. Экологическое районирование исследуемых территорий ранее проводилось только с учетом дозовых нагрузок населения, полученного в результате деятельности бывшего Семипалатинского испытательного полигона. В этой связи необходимо изучение природной геохимической специфики, что позволило бы более точно подходить к вопросу экологической оценки изучаемых территорий с учетом комплексного воздействия природных и техногенных факторов. Цель: комплексное изучение элементного состава компонентов природной среды на территории, прилегающей к бывшему Семипалатинскому испытательному полигону. Объекты: компоненты природной среды (почва, солевые отложения питьевой воды, продукты питания, биологические объекты). Методы. Комплекс компонентов природной среды отбирался в жилых дворах – максимально сближено во времени и пространстве. Главным критерием при выборе исследуемых жилых дворов был факт проживания респондентов в них не менее 10 лет. После соответствующей подготовки образцы отобранных компонентов исследовались с помощью инструментального нейтронно-активационного анализа. Результаты. Показаны результаты комплексного изучения элементного состава компонентов природной среды (почва, солевые отложения питьевой воды), биологических объектов и продуктов питания на территориях, испытывающих воздействие бывшего Семипалатинского испытательного полигона. В исследуемых компонентах природной среды установлены элементы-индикаторы воздействия ядерного техногенеза, а также региональная специфика химического состава природной среды исследуемой территории в целом, проявляющаяся в накоплении U и Zn.
PENGARUH SERTIFIKASI GURU TERHADAP PROFESIONALISME, PENGEMBANGAN DIRIBERKELANJUTAN DAN KEPUASAN KINERJA GURU IPS MAN Se Kota MALANG PASCASERTIFIKASI
Authors: Zuhroh Ni’matuz 
Published: April 2019

<p>This study aims to determine the effect of Teacher Certification on Professionalism, Sustainable Self Development, and Job Satisfaction Teachers IPS MAN Malang Post- Certification. This study uses a quantitative approach and data taken by means of cross- section data collected at the same time from many subjects and retrieval of this data is only done once. In this research the data collection method used is by using questionnaire (questionnaire) that is given to all teachers IPS MAN Se Malang city that has been certified. Primary data taken are data about teacher professionalism, ongoing self-development and job satisfaction. While the questionnaire about teacher performance is filled by the Principal. Other secondary data is the number of teachers who have certification / teacher identity already certified. Measurement scale for primary data by using Likert Scale. Testing data used validity and reliability test. The result of this research is that Teacher Certification to Professionalism, Self Development and Work Satisfaction of Teacher IPS MAN Malang Post Certification ". Influence significantly.</p><p><strong>Keywords: </strong>Teacher Certification, Professionalism, Self-sustained Development and Performance Satisfaction</p>
PENGARUH GAYA BELAJAR MAHASISWA TERHADAP HASIL BELAJAR PADA MATAKULIAH TEORI EKONOMI MIKRO JURUSAN PIPS UIN MAULANA MALIK IBRAHUM MALANG
Authors: Pusposari Luthfiya Fathi 
Published: April 2019

<p>Microeconomic theory course is compulsory subjects that must be taken a student of Social Sciences Education in UIN Maulana Malik Ibrahim Malang. Field conditions, it was found that students who prefer other subjects contained in Social Sciences such as sociology, geography and history than economic subjects, it is condition makes the results need to be improved. Many factors determine the learning outcomes of students, one of which is a learning style that is used. The purpose of this study is describe the influence of learning styles on student learning outcomes at the course of microeconomic theory in PIPS UIN Maulana Malik Ibrahim Malang, while the type of research is quantitative research with data analysis using multiple linear regression. The results showed the influence of the learning styles of students in the course of microeconomic theory to the learning outcomes, partially and simultaneously there is a positive effect but not significant, so the study received Ho. This is possible because the students know learning style but is not accompanied by quantity and the quality of learning, and the views from there are as many models of determination values above 75% are influenced by other variables.</p><p> </p><p><strong>Keywords</strong>: learning styles, microeconomic theory and learning outcomes</p>
Las dos dimensiones de Valle-Inclán
Authors: Aláez Ignacio García 
Published: April 2019

Quiero resaltar en este ensayo la concomitancia que se da en algunos escritores entre su vida y su obra. En el caso de Valle -Inclán, existe un gran paralelismo con otros autores clásicos principalmente con Quevedo, a propósito de su constante prurito de llamar la atención y no pasar desapercibidos. Incluso hay una notoria similitud con ellos en sus peyorativas relaciones con otros autores a quienes consideraba inferiores o con quienes mantenía una enconada desavenencia como podemos apreciar en sus numerosas anécdotas. Asimismo, le une a ellos lo más importante desde el punto de vista literario: su constante búsqueda por crear un estilo nuevo, modernizando y renovando el lenguaje hasta límites insospechados.
Mobile Technology
Authors: Fox Evan Michael 
Published: April 2019

The advancement of mobile communication technology has contributed to an increasingly interconnected world; however, these devices are not being used as effectively as they could be to improve global challenges. One challenging issue is the lack of preparation college graduates receive to positively contribute to the needs of an interdependent global society. Organizations such as UNESCO, NAFSA, and the OECD have recently declared the critical need for the rising generation to strengthen their global competence, the capacity to examine societal issues and work alongside those of various backgrounds to make a change. School instructors are crucial to preparing students to thrive in multicultural societies and address present day issues. With a staggeringly high rate of cellular device ownership among college students, mobile devices could be optimally positioned as a multi-functional tool ready to assist students in gaining these skills. This paper proposes that, while mobile devices may have contributed to a growing need for globally competent individuals, they can also be used to expand these capacities within university students. The PISA global competency framework developed by the OECD is used to propose how instructors can use mobile technology and research grounded practices to strengthen global competence in students.
JUAL BELI DALAM PANDANGAN ISLAM
Authors: Shobirin Shobirin 
Published: April 2019

Selling (business) is the exchange of wealth on the basis of mutual willing and the joint agreement. There are four Perversions, namely; (1) Marriage (ijab qobul) (2) the prescribed is run (subject) (3) ma›kud ‹alaih (object) useful objects according to the view of syara› (4) there is a replacement for exchange of goods. The legality of ijab qobul conditions there are three; (a) Do Not in intersperse with other words between ijab qobul, (b) people - the prescribed is run (seller and buyers ) and (c) do not there separated the meaning the seller and buyers still no interaction about ijab qobul. Conditions of the legality of the seller and buyers there are four; (a) reached puberty understanding. (b) Moslems, this condition specifically for buyers in certain objects objects (c) no objects or items in chairman voterâ (ma›kud alaih) and (d) not wasted (waste), the will of their own and there is no compulsion of the other party. Conditions of the legality of goods sold voterâ there are six; (a) must be holy (b) cannot be not to associate with something (c) cannot be in the limit time (d) its own, (e) can be known (seen), (f) can be known to the quality and the weight. various kinds of selling (business) in Islam, seen from the point of view of the two glass eyes of Islamic law there are two valid and cancel and from the eye of goods there are three (1) selling goods that appear, (2) selling mentioned the pharmacodynamic him in the promise and( 3) selling things that are not there. In Islam in business provide current accounts allow to choose to cancel the marriage of selling (business) called khiar, there are <br />three, namely; (1) khiar, assembly (2) khiar conditions (3) khiar disgrace. The wisdom of selling in Islam; (a) that selling (business) in Islam can be valuable social or helped against each other, will grow berbagain reward, (b) business in Islam is one of the ways to maintain cleanliness and halalnya items eaten for himself and his family, (c) business in Islam is the way to combat laziness, unemployment and extortion to others.
ANALISIS PELAKSANAAN PROGRAM KEMITRAAN DALAM RANGKA PEMBERDAYAAN UKM (Studi Kasus Program Kemitraan PT TELKOM Cabang Palu Sulawesi Tengah)
Authors: Fitria Ria , Jurana Jurana 
Published: April 2019

This research aims to know the system and the procedure for the implementation of the partnership program and its influence on the quality of the SMBS become partner PT Telkom. This laboratory <br />of the adoption by the exportation of cases the implementation of the partnership program which occurs on PT Telkom. The results of this research can be used as a reference for students, faculty and researchers who wish to develop further research. In addition, this research is also useful as early studies to evaluate the implementation of the partnership <br />program which is in PT Telkom Branches Palu.The research method used is the method of descriptive analysis based on the case study, namely approach which compare the conceptual characteristics, SOP system and folow-up procedures partnership program on PT Telkom compared with empiric phenomenon that occurs on PT Telkom Branches Palu. The sources of the data obtained through several ways by observation, interview, study document and the questioner from the secondary data. Through the evaluation that has been done, the authors conclude <br />that there is a discrepancy in some of the things in the implementation of the company operational standards (SOP) partnership program on CDC Unit PT Telkom Branches Palu, and not decide the implementation of internal control especially CDC unit that causes the implementation and the achievement of the purpose of the partnership program has not <br />been achieved. Based on the results of research can be recommended to PT Telkom for more maximize the construction process such as training or business consulting periodically. In addition, increase the number of CDC Unit staff to maximize performance. While, suggestions for SMBS expected to make financial reports regularly and actual.
KONTRAK PEMBIAYAAN MURABAHAH DAN MUSAWAMAH
Authors: Ilyas Rahmat 
Published: April 2019

Islamic bank is a financial intermediary (Intermediary Financial Institution) whose operations are free from elements that are forbidden by Islam, namely gambling, Gharar, Riba, Ryswah, and falsehood.Thus different from conventional banks whose. operations using the principles of interest by most scholars say the same as usury. The element that distinguishes Islamic bank with a conventional bank is the necessity of Shariah Supervisory Board (DPS) under the auspices of the National Sharia Council of the Indonesian Ulema Council (DSN-MUI). <br />Shariah Supervisory Board (DPS) is to monitor the operation of the bank and the products it releases in order to remain in accordance with the provisions of Shari’ah. Murabaha is a contract of sale of goods by <br />the price of the goods plus an agreed profit margin. Based on the bank’s sale and purchase agreement to buy the goods ordered by and sold to customers. Bank selling price is the purchase price of the supplier plus an agreed profit.
APLIKASI MAQASID ASY-SYARI‘AH PADA SISTEM KEUANGAN SYARIAH
Authors: Zaki Muhammad , Cahya Bayu Tri 
Published: April 2019

Maqas'id asy-shari’ah is relevant koredor as a basis for the development of the system, practice, and sharia banking products. The order of maqas'id asy-shari’ah is the way the light for the journey of <br />sharia banking in answer the question dynamic based on the common good and welfare. The concept of Islamic economy is a prerequisite that must be developed further, not only in the conceptual overtones teapi also in practical overtones, especially in the practice of sharia banking. Islam has been providing textual sources that adequate to provide <br />limitations prioritising man, but it is not enough if not balanced with social inferensi. The theory maqas'id asy-shari’ah in the study of the Islamic economy is a step forward in the development of Islamic economic model that most ideal. This is because the maqas'id asyshari’ah can be used as the tool to help resolve the argument in specify a law in order to achieve the goal of shortening the law.