bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of activation energies for dissociation of host‐guest complexes in the gas phase using low‐energy collision induced dissociation
Authors: Bayat Parisa , Gatineau David , Lesage Denis , Marhabaie Sina , Martinez Alexandre , Cole Richard B. 
Published: February 2019

AbstractA low‐energy collision induced dissociation (CID) (low‐energy CID) approach that can determine both activation energy and activation entropy has been used to evaluate gas‐phase binding energies of host‐guest (H‐G) complexes of a heteroditopic hemicryptophane cage host (Zn (II)@1) with a series of biologically relevant guests. In order to use this approach, preliminary calibration of the effective temperature of ions undergoing resonance excitation is required. This was accomplished by employing blackbody infrared radiative dissociation (BIRD) which allows direct measurement of activation parameters. Activation energies and pre‐exponential factors were evaluated for more than 10 H‐G complexes via the use of low‐energy CID. The relatively long residence time of the ions inside the linear ion trap (maximum of 60 s) allowed the study of dissociations with rates below 1 s−1. This possibility, along with the large size of the investigated ions, ensures the fulfilment of rapid energy exchange (REX) conditions and, as a consequence, accurate application of the Arrhenius equation. Compared with the BIRD technique, low‐energy CID allows access to higher effective temperatures, thereby permitting one to probe more endothermic decomposition pathways. Based on the measured activation parameters, guests bearing a phosphate (―OPO32−) functional group were found to bind more strongly with the encapsulating cage than those having a sulfonate (―SO3−) group; however, the latter ones make stronger bonds than those with a carboxylate (―CO2−) group. In addition, it was observed that the presence of trimethylammonium (―N(CH3)3+) or phenyl groups in the guest's structure improves the strength of H‐G interactions. The use of this technique is very straightforward, and it does not require any instrumental modifications. Thus, it can be applied to other H‐G chemistry studies where comparison of bond dissociation energies is of paramount importance.
Viral pathogens associated with acute respiratory illness in hospitalized adults and elderly from Zagreb, Croatia, 2016 to 2018
Authors: Civljak Rok , Tot Tatjana , Falsey Ann R. , Huljev Eva , Vranes Jasmina , Ljubin‐Sternak Suncanica 
Published: February 2019

AbstractAimsTo investigate the viral etiology of acute respiratory infection (ARI) in hospitalized adults and elderly patients in Croatia, compare the prevalence of detected viruses, and to determine clinical characteristics and seasonal occurrence of investigated infections.MethodsFrom January 2016 to June 2018, a total of 182 adult patients presented with symptoms of ARI and admitted to the hospital were tested for 15 respiratory viruses by multiplex reverse‐transcription polymerase chain reaction. Clinical data were collected by retrospective analysis of the patient's chart.ResultsA virus was identified in 106 (58.5%) of the patients. The most commonly detected virus was influenza virus (41.5%), followed by respiratory syncytial virus (13.8%), human metapneumovirus (13.0%), parainfluenza viruses (12.2%), rhinoviruses (11.4%), adenovirus and coronaviruses with equal frequencies (3.3%), and enterovirus (1.6%). The serum level of C‐reactive protein and white blood cell count were significantly lower in patients with respiratory viruses identified when compared with those in whom no virus was detected (P < 0.001 and
P = 0.007, respectively). There were no differences in clinical symptoms according to the type of the detected virus, except for more frequent illness exposure recall for influenza infection (
P = 0.010). Influenza, parainfluenza, and pneumoviruses were detected mostly in winter months, while rhinoviruses in autumn and spring.ConclusionsIn addition to influenza, pneumoviruses, rhinoviruses, and parainfluenza viruses play an important role in etiology of ARIs in adults. Fast and accurate laboratory diagnosis for respiratory viruses in routine practice is needed for clinicians optimally manage patients with ARI and potentially avoid the unnecessary use of antimicrobial drugs.
Cover Image, Volume 99, Issue 5
Authors: Wu Qixian , Zhang Zhengke , Zhu Hong , Li Taotao , Zhu Xiangrong , Gao Huijun , Yun Ze , Jiang Yueming 
Published: February 2019

The cover image is based on the Research Comparative volatile compounds and primary metabolites profiling of pitaya fruit peel after ozone treatment by Qixian Wu et al., DOI: 10.1002/jsfa.9479.
image
Robotic surgery for gallbladder cancer: Operative technique and early outcomes
Authors: Goel Mahesh , Khobragade Krunal , Patkar Shraddha , Kanetkar Amol , Kurunkar Sagar 
Published: February 2019

AbstractBackgroundThe objective was to elucidate the operative technique of robotic radical cholecystectomy (RRC) and to compare the early outcomes of RRC with open radical cholecystectomy (ORC) for gallbladder cancer (GBC).MethodsPatients who underwent RRC for suspected or incidental GBC between July 2015 and August 2018 were analyzed. Patients who underwent ORC during the same period and fulfilled the study criteria formed the control group.ResultsDuring the study period, 27 patients who underwent RRC formed the study group (group A) and 70 matched patients who underwent ORC formed the control group (group B). Median surgical time was higher in group A (295 vs 200 minutes, P < 0.001). However, median blood loss (200 vs 600 mL, P < 0.001), postoperative hospital stay (4 vs 5 days, P = 0.046) and postoperative morbidity (1 vs 15 patients, P = 0.035) were lower in group A. Median lymph node yield was 10 (range = 2‐21) for group A and 9 (range = 2‐25) for group B, and was comparable (P = 0.408). During a median follow up of 9 (1‐46) months, two patients in group A developed recurrence (no port site recurrence).ConclusionRRC is safe and feasible and the short‐term results are compared with ORC.
Development and application of SBA‐15 assisted electromembrane extraction followed by corona discharge ion mobility spectrometry for the determination of Thiabendazole in fruit juice samples
Authors: Mohammadi Nilash Mohammadreza , Mirzaei Fahimeh , Fakhari Ali Reza 
Published: February 2019

AbstractA new sample preparation method based on SBA‐15 assisted electromembrane extraction coupled with corona discharge ion mobility spectrometer was developed for the determination of Thiabendazole as a model basic pesticide in fruit juice samples. The addition of SBA‐15 in the supported liquid membrane in electromembrane extraction system not only can lead to enhancement of the effective surface area, but also introducing the negatively charged silanol groups into supported liquid membrane might improve migration of positively charged analytes toward the supported liquid membrane and finally into the acceptor solution. To investigate the effect of the presence of SBA‐15 in the supported liquid membrane on the extraction efficiency, a comparative study was carried out between the conventional electromembrane extraction and SBA‐15/electromembrane extraction methods. Under the optimized conditions, SBA‐15/electromembrane extraction method showed higher extraction efficiencies in comparison with conventional electromembrane extraction method. SBA‐15/electromembrane extraction method exhibited a low limit of detection (0.9 ng/mL), high preconcentration factor (167) and high recovery (83%). Finally, the applicability of SBA‐15/electromembrane extraction method was studied by the extraction and determination of Thiabendazole as a model basic pesticide in fruit juice samples.
Prognostic indicators of survival in sinonasal extranodal natural killer/T‐cell lymphoma
Authors: Varelas Antonios N. , Ganti Ashwin , Eggerstedt Michael , Tajudeen Bobby A. 
Published: February 2019

ObjectivesExtranodal natural killer/T‐cell lymphoma (ENKTL) is a highly aggressive tumor of the sinonasal tract associated with poor overall survival (OS). This study expands upon epidemiologic, prognostic, and treatment factors for OS and disease‐specific survival (DSS), incorporating newly accessible chemotherapy data.MethodsRetrospective population‐based cohort study performed on cases of sinonasal ENKTL identified through the Surveillance, Epidemiology, and End Results database. Univariate Kaplan‐Meier analysis and subsequent multivariate Cox‐regression analysis were performed to evaluate prognostic and treatment variables for OS and DSS.ResultsFour hundred and sixty cases of sinonasal ENKTL were identified. Five‐year OS and DSS were 46% and 56%, respectively. On multivariate analysis, higher Ann Arbor stage was associated with worse OS (P< 0.001) and DSS (P< 0.001), whereas administration of radiotherapy was associated with improved OS (P< 0.001) and DSS (P= 0.001). Additionally, a higher age at diagnosis was associated with reduced OS (P= 0.024). Chemotherapy was associated with improved OS (P< .01) and DSS (P= .04) for Ann Arbor stage I disease. Surgery was not associated with improved survival.ConclusionThis represents the first study to investigate the use of chemotherapy for the treatment of sinonasal ENKTL using population‐based analysis. Radiation therapy and chemotherapy significantly improve survival in all Ann Arbor stage patients and early‐stage patients, respectively. Early‐stage disease is significantly associated with improved survival. With no established treatment regimen for sinonasal ENKTL, these findings suggest combination chemoradiation is an effective therapy for prolonged survival, especially in early stages of disease.Level of Evidence3Laryngoscope, 129:2675–2680, 2019
Facile Access to Completely Deuterated Single‐Chain Nanoparticles Enabled by Intramolecular Azide Photodecomposition
Authors: Rubio‐Cervilla Jon , Malo de Molina Paula , Robles‐Hernández Beatriz , Arbe Arantxa , Moreno Angel J. , Alegría Angel , Colmenero Juan , Pomposo José A. 
Published: February 2019

AbstractAccess to completely deuterated single‐chain nanoparticles (dSCNPs) has remained an unresolved issue. Herein, the first facile and efficient procedure to produce dSCNPs is reported, which comprises: i) the use of commercially available perdeuterated cyclic ether monomers as starting reagents, ii) a ring‐opening copolymerization process performed in bulk to produce a neat dSCNP precursor, iii) a standard azidation reaction to decorate this precursor with azide moieties, and iv) a facile intramolecular azide photodecomposition step carried out under UV irradiation at high dilution providing with highly valuable, completely deuterated soft nano‐objects from the precursor. dSCNPs are used to investigate by means of neutron‐scattering measurements the form factor (radius of gyration, scaling exponent) of polyethylene oxide (PEO) chains in nanocomposites with different amounts of dSCNPs. Moreover, to illustrate the possibilities offered by the synthetic route disclosed in this communication for potential applications, the significant reduction in viscosity observed in a pure melt of polyether‐based single‐chain nanoparticles when compared to a melt of the corresponding linear polymer chains is shown.
Glycolipid composition of the heterocyst envelope of Anabaena sp. PCC 7120 is crucial for diazotrophic growth and relies on the UDP‐galactose 4‐epimerase HgdA
Authors: Shvarev Dmitry , Nishi Carolina N. , Maldener Iris 
Published: February 2019

AbstractThe nitrogenase complex in the heterocysts of the filamentous freshwater cyanobacterium Anabaenasp. PCC 7120 fixes atmospheric nitrogen to allow diazotrophic growth. The heterocyst cell envelope protects the nitrogenase from oxygen and consists of a polysaccharide and a glycolipid layer that are formed by a complex process involving the recruitment of different proteins. Here, we studied the function of the putative nucleoside‐diphosphate‐sugar epimerase HgdA, which along with HgdB and HgdC is essential for deposition of the glycolipid layer and growth without a combined nitrogen source. Using site‐directed mutagenesis and single homologous recombination approach, we performed a thoroughly functional characterization of HgdA and confirmed that the glycolipid layer of the hgdAmutant heterocyst is aberrant as shown by transmission electron microscopy and chemical analysis. The hgdA gene was expressed during late stages of the heterocyst differentiation. GFP‐tagged HgdA protein localized inside the heterocysts. The purified HgdA protein had UDP‐galactose 4‐epimerase activity in vitro. This enzyme could be responsible for synthesis of heterocyst‐specific glycolipid precursors, which could be transported over the cell wall by the ABC transporter components HgdB/HgdC.
A comparison study of deep muscle sparing transverse rectus abdominis musculocutaneous flap for breast reconstruction
Authors: Tokumoto Hideki , Akita Shinsuke , Arai Minami , Kubota Yoshitaka , Kuriyama Motone , Mitsukawa Nobuyuki 
Published: February 2019

BackgroundBreast reconstruction by deep inferior epigastric perforator flap (DIEP) involves only little rectus abdominis muscle sacrifice. However, the operative procedure may get complicated. We propose here a novel method involving two adjacent perforators and requiring the addition of only the superficial muscle to the flap. This novel technique, termed “deep muscle sparing transverse rectus abdominis musculocutaneous flap (DMS‐TRAM),” was compared to DIEP and MS‐TRAM groups.MethodsThe subjects were 70 patients. The indication of DMS‐TRAM was the distance between two perforators penetrating the deep fascia was <3 cm, and the two perforators ran through the superficial layer of the muscle until they became confluent. All patients were evaluated by contrasting computed tomography. The data of age, body mass index, flap volume, operative time, blood loss, laterality, immediate reconstruction, prior radiation, smoking, re‐exploration, total flap necrosis, partial fat necrosis, and abdominal bulging were compared. Ultimately, DMS‐TRAM was applied in 20 subjects (28.6%), DIEP in 31 (44.3%), and MS‐TRAM in 19 (27.1%).ResultsThe volume of blood loss in the DIEP group was significantly higher than that in the DMS‐TRAM group (328 ± 182 vs 454 ± 217 mL, p = 0.02), the other factors did not significantly influence. The rate of fat necrosis in DIEP tended to be high (10.0% vs 22.6%, p = 0.22).ConclusionsBecause DMS‐TRAM could preserve the deep muscle and penetrating side of intercostal nerve, it could be performed less sacrifice and there were few bleeding and partial necrosis at the same level as MS‐TRAM. DMS‐TRAM was effective in the applied cases.
Modified duobinary modulation of optical signals generated by silicon‐based microring resonator
Authors: Sadegh Amiri Iraj , Addanki Satish , Sampathkumar Arumugam , Dhasarathan Vigneswaran , Yupapin Preecha 
Published: February 2019

AbstractMulti‐wavelength can be generated using microring resonator systems. To transmit these optical signals over a long distance optical communication link, a modulation technique is required. In this research, the modified duobinary modulation technique has been utilized to modulate the generated multi‐wavelength from the microring resonator system. We have de‐multiplexed the multi‐wavelength to single frequencies which undergo a modulation and transmission over a fiber link with a length of 50 km. The performance of the proposed pulse code modulation technique has been analyzed by presenting the quality factor versus the optical input power, eye diagram, and received power for different optical fiber length. The results show the high‐quality signals received with a high‐quality factor and to the best of our knowledge, no analysis has been reported on the microring resonator system using the modified duobinary modulation technique. The results show a maximum quality factor of 12.556 which can be obtained for the input power of −10.11 dBm with the optical fiber length of 50 km, where the bit error rate (BER) was 1.29 × 10−27. The quality factor drops to lower values for the longer optical fiber length linearly as it has the lowest value of 5.023 for optical fiber length of 70 km. The analysis has been performed over system parameter optimizations.
Microstrip Gasper‐Peano fractal antenna for circular polarization applications
Authors: Rajabloo Hossein , Mandali Javad 
Published: February 2019

AbstractIn this article, a slot array antenna with circular polarization is presented. The structure is designed based on GasperPeano fractal as a feed line. By use of the Minimum mean square error method, the array has been optimized for the best radiation power. First, the theory of a single feed line with a radiation element is presented, then extend this theory to the double and N radiation elements. At each step, the coupling factor and radiation power are calculated. And three error function is defined as goal functions for reaching uniform distribution, maximum efficiency and the combination of them. Due to the goal functions, a genetic algorithm is represented to reach the best results by altering and tuning the parameters. The circular polarization bandwidth of the final structure is 5%, and the radiation efficiency is 85%. This theory and structure can be useful for making circular polarization in applications.
Compact design of trapezoid shape monopole antenna for SWB application
Authors: Rahman Saeed Ur , Cao Qunsheng , Ullah Habib , Khalil Hisham 
Published: February 2019

AbstractIn this article, a compact design of the monopole antenna is proposed for the super‐wideband application (SWB). The extremely wide frequency bandwidth is achieved by deploying a topology based on trapezoid shape radiator, triangular tapered feed line, and semicircular ground. The antenna shows resonance from 1.42 GHz to more than 90 GHz with a bandwidth ratio of 63.30:1, VSWR ≤2 and with S11 ≤ −10 dB. The electrical dimension of the monopole antenna is 0.16λc × 0.27λc where the wavelength λc is with respect to the lowest cut‐off frequency. The designed monopole antenna is fabricated on the F4B substrate. The prototype is experimentally validated for ultrawideband and SWB application. The experimental and simulated results are in good agreement and the designed antenna shows better performance of a wideband operation, compact electrical dimension, and high bandwidth dimension ratio over existing reported structures. The proposed antenna can be used for multiple bands such are ISM, Wi‐Fi, WLAN, WiMAX, C, S, X, K, and Ku bands.
Comparative investigation of CSRZ‐DQPSK, DRZ‐DQPSK, and MDRZ‐DQPSK modulation techniques in MDM IS‐OWC system
Authors: Gill Harpreet Kaur , Grewal Narwant Singh , Walia Gurjot Kaur 
Published: February 2019

AbstractThe article presents the comprehensive approach of designing MDM in Inter‐Satellite OWC system using CSRZ‐DQPSK, DRZ‐DQPSK, and MDRZ‐DQPSK modulation system. The 64 Laguerre Gaussian modes are integrated to enhance the system's capability. The proposed system is designed for 64 channels having distances varied from 900 to 4500 km at various data rates. The mode division multiplexing concept is implemented over WDM because it uses single laser source and enhance the capacity of optical networks. Performance of proposed system is examined by comparing the eye diagrams and Q‐factor. It is observed from the outcomes that MDRZ‐DQPSK modulation presents superior Quality factor of 19.42 then DRZ‐DQPSK and CSRZ‐DQPSK Modulation with the favorable distance upto 4500 km at 10 Gbps bit rate. MDRZ‐DQPSK modulation technique performs well till 40 Gbps whereas CSRZ‐DQPSK Modulation exhibits least Q‐factor due to high consumption of bandwidth but it saves cost and preferable for long reach transmission.
A new RFID monopole antenna using a compact AMC structure
Authors: Elzuwawi Hifa H. , Tahseen Muhammad M. , Elzwawi Ghada H. , Denidni Tayeb A. 
Published: February 2019

AbstractA new compact artificial magnetic conductor (AMC) based coplanar waveguide (CPW) antenna is presented for RFID applications. The antenna is designed with hexagonal ring and patch elements. The proposed AMC with an electrical size of 0.02
λ0 is designed as a reflector for a monopole antenna which improves the antenna gain from 2 to 6.7 dBi. The monopole antenna is designed using cascaded hexagonal patch and ring elements. The simulated and experimental performance of the proposed antenna are presented in terms of return loss, gain and radiation patterns, with and without the presence of AMC. The performance of the antenna is evaluated at 868 MHz (European RFID Band). The obtained results exhibit good agreement. The proposed antenna provides compactness, cost efficiency, higher gain, and higher radiation efficiency (at 868 MHz).
Malnutrition Impacts Health‐Related Quality of Life in Cirrhosis: A Cross‐Sectional Study
Authors: Chiu Elaine , Marr Kaleb , Taylor Lorian , Lam Louisa , Stapleton Melanie , Tandon Puneeta , Raman Maitreyi 
Published: February 2019

AbstractBackgroundTo explore the influence of nourishment state measured by various nutrition assessment tools (NATs) on health‐related quality of life (HRQoL) in a pretransplant population with cirrhosis.MethodsWe collected demographic, nutrition assessment, and disease specific data on 81 patients. HRQoL was measured with the Short‐Form 36 and divided into 8 subscales. Significant relationships between NATs and HRQoL were examined using independent sample t‐tests, χ2 analyses, correlations, and multiple and logistic regression adjusted for age and gender.ResultsStudy mean age was 54.2 years (SD 10.4 years), and 57% were male. Subjective Global Assessment (SGA) was significantly related to all HRQoL subscales, except bodily pain and mental health. In the adjusted regression models, general health, vitality, and social functioning were all significantly lower in patients with poorer nutrition status measured using SGA (adjusted R2 = 11%, β = −0.34, p < 0.01; adjusted R2 = 8%, β = −0.27, P < 0.05; and adjusted R2 = 12%, β = −0.38, P < 0.01, Q4 respectively). Physical functioning improved as hand grip strength increased (adjusted R2 = 20%, β = 0.36, P < 0.01). MELDNa demonstrated a significant negative relationship with role‐emotional (adjusted R2 = 3%, β = 0.25, P < 0.05), and mid‐arm circumference did not demonstrate any significant relationships with HRQoL.ConclusionsMalnutrition assessed by SGA is associated with lower HRQoL in patients with cirrhosis. Future research should identify if nutrition interventions can effectively improve HRQoL in cirrhosis patients.
Long‐Term Follow‐up of the Mind Your Health Project: Acceptance‐Based versus Standard Behavioral Treatment for Obesity
Authors: Forman Evan M. , Manasse Stephanie M. , Butryn Meghan L. , Crosby Ross D. , Dallal Diane H. , Crochiere Rebecca J. 
Published: February 2019

ObjectiveIn the Mind Your Health Trial, acceptance‐based behavioral treatment (ABT) for obesity outperformed standard behavioral treatment (SBT) at posttreatment. This trial compared effects over 2 years of follow‐up.MethodsParticipants with overweight or obesity (n = 190) were randomized to 25 sessions of SBT or ABT over 1 year and assessed at months 12 (i.e., posttreatment), 24 (1 year posttreatment), and 36 (2 years posttreatment).ResultsWeight‐loss differences previously observed at 12 months attenuated by follow‐up, though a large difference was observed in the proportion of treatment completers who maintained 10% weight loss at 36 months (SBT = 17.1% vs. ABT = 31.6%; P = 0.04; intent‐to‐treat: SBT = 14.4% vs. ABT = 25.0%; P = 0.07). The amount of regain between posttreatment and follow‐up did not differ between groups. ABT produced higher quality of life at 24 and 36 months. Autonomous motivation and psychological acceptance of food‐related urges mediated the effect of condition on weight. No moderator effects were identified.ConclusionsOverall, results suggest that infusing SBT for weight loss with acceptance‐based strategies enhances weight loss initially, but these effects fade in the years following the withdrawal of treatment. Even so, those receiving ABT were about twice as likely to maintain 10% weight loss at 36 months, and they reported considerably higher quality of life.