bluuebunny/crossref_metadata_2025_split huggingface dataset:
MODEL MATERI GELAP DUA FLUIDA STATIS DENGAN TAMBAHAN KONSTANTA KOSMOLOGI
Authors: Supriyadi Izrul , Sawitar Widya , Budi Esmar , Fahdiran Riser 
Published: August 2018

Abstrak
Pada persamaan medan gravitasi Einstein terdapat konstanta kosmologi sebagai konstanta alam yang menjelaskan model mengembangnya alam semesta dan yang paling dominan terdapat di jagad raya ini adalah dalam bentuk energi gelap (dark energy). Kami meninjau model objek dua fluida tidak terkopel, seperti layaknya materi gelap (dark matter) atau bintang yang memiliki karakteristik tensor energi-momentum dan kecepatan-4 nya yang berbeda serta bersifat anisotropik, kemudian disatukan sebagai model dua fluida untuk ditinjau persamaan TOV (Tolman-Oppenheimer-Volkoff) dan persamaan geodesiknya dalam menunjukkan sifat gerak dan model dua fluida tersebut. Hasil perhitungan menunjukkan bahwa model ini dapat menjelaskan persamaan potensial efektif dengan tambahan konstanta kosmologi sebagai karakteristik gerak dan kecepatan tangensial partikel uji dalam orbit lingkaran stabil.
Kata-kata kunci: konstanta kosmologi, anisotropik, potensial efektif, kecepatan tangensial.
Abstract
In Einstein's gravitational field equation has been found the cosmological constant as the natural constant that describes the universe's expansion model and the most dominant in the universe is the dark energy form. We review the two objects of fluid models are not coupled, like dark matter or stars which has the different characteristic energy-momentum tensor and four velocities and anisotropic tend, then combined as two-fluid models for TOV (Tolman-Oppenheimer-Volkoff) equation and the geodesic equation to characterize the movement and the two fluid models. The calculation result shows that this model can explain the potential equation with an addition of an effective cosmological constant as the movement characteristic and tangential velocity of a tested particle in a stable circular orbit.
Keywords: cosmological constant, anisotropic, effective potential, tangential velocity.
Management and Outcome of Transepiphyseal Femoral Neck Fracture-Dislocation with a Transverse Posterior Wall Acetabular Fracture
Authors: Shaath M. Kareem , Shah Harsh , Adams Mark R. , Sirkin Michael S. , Reilly Mark C. 
Published: August 2018

Case:
We present the case of a 10-year-old girl who sustained a transepiphyseal femoral neck fracture with posterior dislocation of the femoral epiphysis and an associated transverse posterior wall acetabular fracture, leading to complete separation of the capital femoral epiphysis. She underwent urgent operative intervention; she was followed for 13 years and achieved an excellent outcome.

Conclusion:
Pediatric hip fracture-dislocations are complex injuries that should be managed by a competent pelvic reconstructive surgeon in a well-resuscitated patient. If a quality reduction is obtained in a timely manner, the patient has the best chance of achieving a favorable long-term outcome.
A EXPRESSÃO REGIONAL DAS UNIVERSIDADES PÚBLICAS NAS CIDADES MÉDIAS DE SOBRAL-CE E PARNAIBA-PI
Authors: Holanda Virgínia Célia Cavalcante de 
Published: August 2018

Sobral e Parnaíba são pensadas nesse artigo como cidades médias do Nordeste Brasileiro, localizadas a uma distancia de 252 km uma da outra, tem na história de formação e no dinamismo do presente aconteceres e usos que as aproximam. Sendo a expansão do Ensino Superior público e privado uma das variáveis de grande força no espaço urbano regional do período atual. Por entender que a universidade pública é historicamente a de maior penetração no cenário regional e pela necessidade de síntese, selecionamos o Campus da Universidade Federal do Piauí (UFPI) e em Sobral selecionamos a Universidade Estadual Vale do Acaraú (UVA), ambas inauguram nos seus espaços a oferta do ensino superior público a mais de quatro décadas. Os procedimentos metodológicos foram pesquisa bibliográfica, pesquisa documental, trabalho de campo e entrevista com gestores.
Structure Based Identification of Potential Inhibitors of NS3 Protein of Zika Virus
Authors: Faizan Md. Imam , Naqvi Abu Turab , Hassan Md. Imtaiyaz , Abdullah Mohd. , Tazeen Ayesha , Shafat Zoya , Hisamuddin Malik , Alam Aftab , Ali Shahnawaz , Ali Sher , Farooqui Anam , Hamza Abu , Parveen Nazish , Deeba Farah , Ahmed Anwar , Parveen Shama 
Published: August 2018

Background:The re-emerging Zika virus has posed a serious threat to human health due to its association with the neurological disorders. The NS3 protein of Zika virus plays a pivotal role in the genome replication and thus may prove to be a critical target for the drug designing studies.Objective:The present study was conceptualized to analyze the crystal structure of NS3 protein of Zika virus followed by the identification of it’s potential inhibitors.Methods:Crystal structure of the NS3 protein was evaluated in detail. Docking of the NS3 protein was done with 130 different ligands including dengue virus inhibitors and their similar compounds along with some approved drugs. The drug likeliness properties were checked for non drug compounds.Results:Structural analysis of the NS3 protein revealed three important sites namely ATP- and RNAbinding sites as well as a central cavity. The selected ten ligands (ZINC05487635, ZINC0092398, ZINC13345444, 4-methoxyphenyl 4-chloro-3-nitrobenzoate, Luteolin, Ivermectin, Suramin, Dasatinib, Panduratin A, and ARDP0009) showed a higher binding affinity for the NS3 protein and good drug likeliness properties.Conclusion:These inhibitors could possibly act as potential lead molecules for future drug designing studies. Our present computational data is envisaged to be useful for gathering experimental evidences towards the development of potential therapeutic molecules against this arthropod mediated pathogen.
α-Aroylketene Dithioacetal Mediated Synthesis of (E)-3-(benzo[d]thiazol-2-ylamino)-2-(1-methyl-1H-indole-3-carbonyl)-3-(methylthio)acrylonitrile Derivatives and their Biological Evaluation
Authors: Bhale Pravin S. , Chavan Hemant V. , Dongare Sakharam B. , Sankpal Sagar T. , Bandgar Babasaheb P. 
Published: August 2018

Background:
The blending of two pharmacophores would generate novel molecular templates that
are likely to exhibit interesting biological properties.

Objective:
A facile, efficient and high yielding synthesis of (E)-3-(benzo[d]thiazol-2-ylamino)-2-(1-methyl-1Hindole-
3-carbonyl)-3-(methylthio) acrylonitrile derivatives and evaluation of therapeutic potential.

Method:
The synthesis of target molecules has been achieved by reacting 2-aminobenzothiazole and substituted
2-(1-methyl-1H-indole-3-carbonyl)-3,3-bis(methylthio)acrylonitrile in the presence of a catalytic amount of
sodium hydride in THF. Structural investigations were carried using 1H NMR, 13C NMR, FT-IR, and HRMS
data.

Results:
In vitro anti-tumor evaluation of the synthesized compounds against MCF-7 (breast carcinoma) cell
line revealed that they possess good anti-tumor activities. Compounds, 4j and 4i demonstrated significant activities
against breast carcinoma (GI50 14.3 and 19.5 µM respectively). Most of the synthesized compounds were
also found to be excellent NO, H2O2, DPPH, and superoxide radical scavengers. Anti-diabetic and antiinflammatory
evaluation also displayed moderate activity.

Conclusion:
Among the compounds synthesized some of the compounds possess significant anticancer, antioxidant
and anti-inflammatory properties.
O SUBDESENVOLVIMENTO E O MEIO AMBIENTE NO BRASIL: INDUSTRIALIZAR PARA PRESERVAR
Authors: Mascarenhas Fábio Sampaio 
Published: August 2018

A pesquisa tem como objeto a análise da interconexão entre o subdesenvolvimento brasileiro e a ineficácia da legislação ambiental no país. Estabelece-se uma crítica ao aparente confronto do desenvolvimento econômico à preservação ambiental. Para tanto, parte-se de premissas do direito econômico brasileiro, pautado na linha do estruturalismo latino-americano. Objetiva-se demonstrar que a questão ambiental nacional deve ser visualizada por meio de uma avaliação das características brasileiras inerentes de sua condição periférica no sistema capitalista. Parte-se, primeiramente, de uma linha teórica que perpassa por três conceitos centrais: A acumulação primitiva de capital, o sentido da colonização e a relação centro-periferia. Em seguida, uma leitura epistemológica da infraestrutura, utilizando, para tanto, apenas os conceitos relevantes para o direito econômico como método. Por último, descreve-se uma síntese da atual regulação ambiental brasileira em contraposição ao que seria o seu “estado da arte”, propondo um diálogo com o artigo 3º, o artigo 170 e o artigo 219 da Constituição Federal, que trazem uma interpretação constitucional da superação do subdesenvolvimento. Em síntese, têm-se como resultados que o debate jurídico-ambiental deve, necessariamente, passar pela busca da superação do subdesenvolvimento. Isso pois, independentemente da qualidade da legislação ambiental, enquanto o centro decisório estiver fora do Brasil e ele se colocar como exportador de matéria prima, a exploração ambiental será extensiva. Partindo de tais premissas, a conclusão da pesquisa é pouco usual: a única forma de desenvolvimento sustentável no Brasil é por meio de melhor infraestrutura e industrialização.
Detección de parvovirus canino por PCR y su asociación con algunos de los factores de riesgo
Authors: Mokhtari Azam , Farmani Naghmeh , Rajabi Milad 
Published: August 2018

Objetivo. El parvovirus canino es una de las enfermedades más importantes en perros en todo el mundo la cual amenaza su salud. El objetivo de este estudio fue determinar la prevalencia del parvovirus canino en perros remitidos a la Clínica de Pequeños Animales de la Universidad de Teherán en la provincia de Teherán por el método de detección del genoma. Materiales y Métodos. Se obtuvieron muestras de heces diarreicas de 60 perros durante los años 2014-2016 y se investigó la presencia de CPV por el método de PCR. Resultados. La prevalencia de infección por parvovirus canino en los perros estudiados fue del 8,33% (5 0f 60). No se encontraron diferencias significativas entre los diferentes grupos de edad y razas. Sin embargo, la infección fue significativamente mayor en perros con diarrea hemorrágica (3 de 25), pero no fue estadísticamente significativa usando la prueba de chi-cuadrada (P>0,05). Conclusiones. Este estudio demostró que la diarrea hemorrágica y la falta de vacunación pueden considerarse como síntomas y factores de riesgo importantes de la infección por parvovirus canino en perros, y que los propietarios de perros en Irán deben ser conscientes del hecho de que la vacunación contra la infección CPV debe hacerse con cuidado y a tiempo para controlar y prevenir el virus.
Involución uterina en vacas Holstein en la provincia El Carchi, Ecuador
Authors: Balarezo U Luís , García-Díaz Juan , Hernández-Barreto Miguel , Vargas-Hernández Silvino 
Published: August 2018

Objetivo. Evaluar la involución uterina en vacas Holstein, en las condiciones de producción de la ganadería bovina lechera en la provincia El Carchi, Ecuador. Materiales y métodos. Se seleccionaron 60 vacas y se determinó el tiempo para la involución uterina mediante la exploración recto-vaginal, ultrasonografía y la puntuación clínica de la regresión del útero. Se determinaron los estadígrafos descriptivos de cada variable. Se evaluó el efecto de la paridad y la condición corporal (CC) sobre la completa involución uterina mediante un ANOVA multifactorial y la prueba LSD para comparar las medias. Resultados. La involución del útero, sin tomar en cuenta la puntuación clínica ocurrió a los 29.86 ± 7.71 días pero considerando esta notación fue a los 42±0.39 días. La involución uterina ocurrió más temprano (p<0.05) en las vacas con CC al parto ≥ que 3.5 que en las que la tenían < de 3.5. En las vacas de segundo parto fue a los 25.17 ± 1.32 días y se prolongó (p<0.05) en el tercero y cuarto parto. La aparición del folículo dominante y la ovulación ocurrieron a los 16.63 ± 3.83 y 27.76 ± 7.71 días, respectivamente. Conclusiones. La involución clínica del útero considerando el examen recto-vaginal ocurrió en menor tiempo que cuando se evaluó considerando la puntuación clínica. El proceso de involución uterina está iinfluenciado por la paridad y la CC al parto.
Development of Microvascular Complications and Effect of Concurrent Risk Factors in Type 1 Diabetes: A Multistate Model From an Observational Clinical Cohort Study
Authors: Bjerg Lasse , Hulman Adam , Carstensen Bendix , Charles Morten , Jørgensen Marit E. , Witte Daniel R. 
Published: August 2018

OBJECTIVE
Type 1 diabetes is a complex disease, and development of multiple complications over time can be analyzed only with advanced statistical methods. This study describes the development of microvascular complications and explores the effect of complication burden and important concurrent risk factors by applying a multistate model.

RESEARCH DESIGN AND METHODS
We used a clinical cohort at the Steno Diabetes Center Copenhagen to study the development of diabetic kidney disease, retinopathy, and neuropathy. We extracted information from electronic patient records and estimated incidence rates of complications by concurrent complication burden. We explored the extent to which concurrent complications modify the effect of selected risk factors on the development of microvascular complications.

RESULTS
We included 3,586 individuals. Incidence rate ratios in individuals with two previous complications were 3.2 (95% CI 2.3–4.5) for diabetic kidney disease, 2.1 (1.5–3.1) for retinopathy, and 1.7 (1.2–2.4) for neuropathy compared with individuals without complications. The models included diabetes duration; calendar time and age as timescales; and sex, HbA1c, lipid-lowering and antihypertensive treatment, systolic blood pressure, BMI, estimated glomerular filtration rate (eGFR), cardiovascular disease (CVD), LDL cholesterol, insulin dose (units/kg/day), and smoking status as covariates. Effects of HbA1c, diabetes duration, systolic blood pressure, BMI, eGFR, and LDL cholesterol where not modified by concurrent complication burden, whereas the effect of sex and CVD were.

CONCLUSIONS
The risk of microvascular complications highly depends on the concurrent complication burden and risk factor profile in individuals with type 1 diabetes. The results emphasize attention to risk factors, regardless of existing number of complications, to prevent development of further microvascular complications.
Analisis Perencanaan Pembelajaran IPA pada Materi Ekosistem Kelas XII SMK Negeri 4 Padang
Authors: Sari Rona Taula 
Published: August 2018

To improve and produce graduated students of SMK relevance with the needs of business and industry, which continues growing significantly, then the vocational curriculum should be designed and implemented the developing competence. Teachers are required to be able to produce learners who are extremely competent and ready to face life's challenges with confidence and high self confidence through a process of meaningful learning that he personally experienced to be able to apply his knowledge in everyday life. Therefore, teachers should be able to design their own learning plan to be based on a curriculum that has been made by the government. Planning learning is an important part in the implementation of education at the school. One lesson plans to be prepared by the teachers is the Learning Implementation Plan (RPP).This type of research is descriptive quantitative research but generally is in the form of case studies. Data collection techniques used in relation to the learning plan in the form of Learning Implementation Plan (RPP) made by teachers in the value of using Instrument RPP (IPKG-1).Based on the results of research on science teaching in the classroom Planning XII-DKV in SMK N 4 Padang on subjects Ecosystem terms of format already referred to the Teacher Performance Assessment Instrument (IPKG-1). Learning materials and learning resources are the criteria are not good (1.00 to 1.99). Teacher Performance Assessment Instrument (IPKG-1) provide an assessment of achieving the expected unfavorable (2.00 to 2.99) for the indicator, learning activities, learning objectives, assessment of learning outcomes. Good enough category (3.00 to 3.49) for kompenen RPP in general, SK and KD, the allocation of time and learning methods. Identity RPP and KD can be implemented in one or more meetings were with the highest fourth in both categories.
Manajemen Konflik Sekolah Regrouping Di SD Negeri Pucangsawit Surakarta
Authors: Suwarto Suwarto 
Published: August 2018

The objectives of the research are to describe: 1) the sources and types of conflict; 2) the conflicts’ management; and 3) the supporting and inhibiting factors in conflict management of regrouped school at State Elementary School Pucangsawit Surakarta. The type of the research is qualitative with naturalistic design. The research was undertaken atState Elementary School Pucangsawit Surakarta. The results are 1) the conflict sources at State Elementary School Pucangsawit Surakarta can be classified into two types of sources, namely the teachers and parents. The conflict types emerged at the form of inter-individual conflict among teachers from the regrouped schools, the conflict in school naming, conflict related to professional tasks and teachers’ administration, and conflict related to students’ administration; 2) the conflict management at State Elementary School Pucangsawit Surakarta were done through planning, organizing, actuating, and controlling. The conflict resolution referring to schools’ rivalry is done by applying fair and positive competition; and 3) the supporting factors in conflict management are the government support and schools’ stakeholder’s awareness. The inhibiting factors cover the self ego that remains existed in some teachers and parents from both of the schools regrouped.
Impact of nitrate therapy on the expression of caveolin-1 and its phosphorylated isoform in lungs in the model of monocrotaline induced pulmonary hypertension
Authors: Kmecova Z. , Malikova E. , Zsigmondova B. , Radik M. , Veteskova J. , Marusakova M. , Krenek P. , Klimas J. 
Published: August 2018

Abstract
Aim: Nitric oxide signalling pathway showed to be one of the crucial factors in the treatment and pathogenesis of pulmonary arterial hypertension. The aim of this study was to determine the effect of administration of inorganic nitrate, NaNO3, on the expression of caveolin-1 and its phosphorylated isoform (pTyr14Cav-1) in lungs in the experimental model of monocrotaline induced pulmonary hypertension.
Methods: 10 weeks old male Wistar rats were subcutaneously injected with 60 mg/kg dose of monocrotaline (MCT) or vehicle (CON). Twelve days after the injection, part of the MCT group was receiving 0.3 mM NaNO3 (MCT+N0.3) daily in the drinking water and rest was receiving 0.08% NaCl solution. Four weeks after MCT administration, the rats were sacrificed in CO2. Protein expression in lungs was determined by western blot.
Results: We observed a significant decrease in the caveolin-1 expression and a significant shift towards the expression of pTyr14Cav-1 in the group treated with nitrate (p < 0.05).
Conclusion: NaNO3 administration affected the expression of caveolin-1 and the ratio of its active (phosphorylated) isoform increased.
New urban recreational spaces. Attractiveness, infrastructure arrangements, identity. The example of the city of Łódź
Authors: Mokras-Grabowska Justyna 
Published: August 2018

Abstract
Services related to leisure time are treated as an important factor in the development of cities - a factor creating urban recreational spaces. It is also important to provide such spaces with appropriate elements of infrastructure, which would contribute to increasing its attractiveness. Urban recreational spaces gain more and more experimental and unique forms and are more and more defined in terms of functionality, aesthetics and identity. This article includes three examples of this type of spaces in Łódź. On the basis of conducted research, there was presented the importance of infrastructure arrangements that are thought-through and “well-anchored” in the urban tissue.
PENINGKATAN PRESTASI BELAJAR PKn MELALUI TUGAS PROYEK BERBANTUAN WEBSITE DI SDN GEGUNUNG KULON, KAB. REMBANG
Authors: - Parlan 
Published: August 2018

ABSTRAKTujuan penelitian ini adalah mendeskripsikan proses pembelajaran, mengetahui peningkatan prestasi siswa, dan mendeskripsikan perubahan perilaku siswa dalam pembelajaran PKn melalui tugas proyek berbantuan website. Penelitian ini dilaksanakan dalam 2 Siklus dengan subjek siswa kelas IV SD Negeri Gegunung Kulon, Kabupaten Rembang, semester 2 tahun pelajaran 2014/2015. Data penelitian dianalisis dengan metode deskriptif komparatif, membandingkan proses dan hasil belajar antara praSiklus, Siklus I dan Siklus II. Hasil penelitian yang dilaksanakan 2 Siklus menunjukkan peningkatan aktivitas siswa sampai 86 persen baik. Hasil belajar siswa juga meningkat ditandai Siklus I nilai rata-rata kelas 67,86 dan ketuntasan mencapai 57 persen. Siklus II nilai rata-rata kelas 78,57 dan ketuntasan 86 persen. Kesimpulan penelitian ini adalah aktivitas dan hasil belajar siswa meningkat dalam mengikuti pembelajaran serta ada perubahan perilaku siswa untuk mengikuti pembelajaran PKn melalui tugas proyek berbantuan website yang semula pasif menjadi lebih aktif. Semua siswa berminat dalam melaksakanan tugas dan memperoleh pengalaman yang menyenangkan dalam menjelajah website atau internet. ABSTRACTThe objective of this research was to describe learning process, to know how students’ learning achievement improve, and to describe the change of student behavior on civics learning through website-assisted project task. The research was done through two cycles, with grade IV students in SD Negeri Gegunung Kulon throughout the second semester of school year 2014/2015 as the subject. Research data analysis was done using descriptive comparative method, comparing the learning process and result between pra-cycle, first cycle and second cycle. The result showed positive increase of students’ activities as much as 86 percent. The improvement of students’ learning achievement in cycle I could be seen by the class average grade of 67,86 and mastery learning of 57 percent, while in cycle II the class average grade was 78,57 and mastery learning of 86 percent. The conclusion was that students’ learning activities and achievement improved and there was also a changing in students’ behavior in learning civics through website-assisted project task, from passive learning to active learning. Every student showed interest in doing the project and gaining enjoyable experience browsing the internet.
Relaciones Públicas ciudadanas.
Authors: Quintana Pujalte Andrea Leticia , Castillo Esparcia Antonio , Carretón Ballester Mª Carmen 
Published: August 2018

La crisis económica de España ha supuesto un aumento de los flujos de comunicación política entre instituciones públicas, medios de comunicación y actores políticos. El contexto de este estudio se centra entre los años 2011-2013, período en el cual España estaba inmersa en un escenario de crisis. En este escenario, se indaga sobre quiénes fueron los actores y los discursos que participaron del proceso de construcción de Opinión Pública respecto de los desahucios en España. Y de qué modo se manifestaron simbólicamente los actores en el espacio público político. A partir del análisis crítico del discurso realizado sobre 1002 unidades de análisis durante el periodo 2011-2013 en España, puede afirmarse que la interpretación hegemónica para la construcción de la opinión pública y la influencia en esta, dadas por el discurso político de la prensa, estuvo guiada en mayor medida por la construcción de la identidad de los afectados como producto de una situación circunstancial en la que fueron engañados, de los indignados desde una postura negativa que condena sus estrategias de acción y de la banca como un actor político que se construye de modo similar en los diarios analizados: como el representante de la estabilidad económica y financiera, y no como uno de los principales artífices de la crisis económica y de vivienda que vivía España.