bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive gene expression analysis for exploring the association between glucose metabolism and differentiation of thyroid cancer
Authors: Suh Hoon Young , Choi Hongyoon , Paeng Jin Chul , Cheon Gi Jeong , Chung June-Key , Kang Keon Wook 
Published: June 2019

Abstract
Background

The principle of loss of iodine uptake and increased glucose metabolism according to dedifferentiation of thyroid cancer is clinically assessed by imaging. Though these biological properties are widely applied to appropriate iodine therapy, the understanding of the genomic background of this principle is still lacking. We investigated the association between glucose metabolism and differentiation in advanced thyroid cancer as well as papillary thyroid cancer (PTC).

Methods

We used RNA sequencing of PTC obtained from the Cancer Genome Archives and microarray data of poorly-differentiated and anaplastic thyroid cancer (PDTC/ATC). The signatures of GLUT and glycolysis were estimated to assess glucose metabolic profiles. The glucose metabolic profiles were associated with tumor differentiation score (TDS) and BRAFV600E mutation status. In addition, survival analysis of glucose metabolic profiles was performed for predicting recurrence-free survival.

Results

In PTC, the glycolysis signature was positively correlated with TDS, while the GLUT signature was inversely correlated with TDS. These correlations were significantly stronger in the BRAFV600E negative group than the positive group. Meanwhile, both GLUT and glycolysis signatures were negatively correlated with TDS in advanced thyroid cancer. The high glycolysis signature was significantly associated with poor prognosis in PTC in spite of high TDS. The glucose metabolic profiles are intricately associated with tumor differentiation in PTC and PDTC/ATC.

Conclusions

As glycolysis was an independent prognostic marker, we suggest that the glucose metabolism features of thyroid cancer could be another biological progression marker different from differentiation and provide clinical implications for risk stratification.
Measurement of Unirrigated Turfgrass Evapotranspiration Rate in the Red River Valley
Authors: Niaghi Ali Rashid , Jia Xinhua , Scherer Thomas , Steele Dean 
Published: June 2019

Core Ideas
Soil moisture is needed in defining well‐watered turfgrass condition in evapotranspiration measurement.
Deep soil moisture supports turfgrass growth when surface soil moisture is not sufficient.
The ETa can be estimated from 0.96 ETo using the ASCE‐EWRI standardized method for well‐watered turfgrass.
The ASCE‐EWRI standardized reference ET equation can be used for water management of turfgrass in northern cool climates and during drought periods.
Turfgrass actual evapotranspiration (ETa) measurements are critical for water management and irrigation scheduling. With no historical ETa measurements in eastern North Dakota, turfgrass ETa rates were measured with the residual method using eddy covariance instrumentation and two arrays of soil moisture sensors on unirrigated turfgrass under natural conditions in the 2011, 2012, and 2013 growing seasons. An on‐site weather station provided weather data to calculate the standardized grass‐based reference evapotranspiration (ETo) (Allen et al., 2005). The daily ETa/ETo ratios were screened using the criteria of soil moisture ≥50% of available water for the top 30 cm of the root zone, rain amounts ≤10 mm, and a recovering period after drought. The screened monthly average ETa/ETo ratios for the unirrigated turfgrass were 1.03, 0.98, 0.94, 0.90, 0.82, and 1.18 from May to October. The mean ETa/ETo ratio for the entire growing seasons was 0.96, implying that the American Society of Civil Engineering–Environmental and Water Resource Institute ETo method was valid for guiding the turfgrass ETa calculation even in unirrigated and cold climate conditions. Because this is the first reported study on ETa measurement of a turfgrass site, the limited data can provide a baseline on water management for turfgrass under various weather conditions in this region. The results indicated that a monthly refinement of ETa/ETo values might be required to maintain the landscape turfgrass quality more precisely in terms of water management.
Metastatic Colorectal Cancer: Prognostic and Predictive Factors
Authors: Nappi Anna , Nasti Guglielmo , Romano Carmela , Berretta Massimiliano , Ottaiano Alessandro 
Published: June 2019

:
Colorectal cancer represents the third most frequently occurring cancer worldwide. In the
last decade, the survival of patients affected by metastatic colorectal cancer (mCRC) has improved
through the introduction of biological drugs. However, in this new and dynamic therapeutic context,
research about prognostic and predictive factors is important to guide the oncologists to effective
therapies as well as to improve the understanding of colorectal cancer biology. Their identification is
an intensive area of research and our future goal will be to depict tumour-specific "molecular signatures"
in order to predict the clinical course of the disease and the best treatments.

:
In this report, we describe clinical, pathological and molecular biomarkers that can play a role as
prognostic or predictive factors in mCRC.
Роль жидкого подслоя Al в качестве катализатора направленного роста нанокристаллов ZnO
Authors: Волчков И.С. , Ополченцев А.М. , Задорожная Л.А. , Григорьев Ю.В. , Каневский В.М. 
Published: June 2019

The study shows for the first time the effect of preformed alloying Al layer
deposited on silicon substrate upon the morphology and orientation growth of
ZnO:Al nanocrystals array. The stages of decay of the alloying Al layer into droplets
of the quasi-liquid phase, from temperature treatment at the initial stage of the
growth according to the vapor-liquid-crystal (VLC) mechanism, are demonstrated.
The schema of growth stages of ZnO nanocrystals according to VLC mechanism, on
Si substrate with a pre-applied layer of the alloying metal, is presented.
Young People’s Attitudes and Motivations Toward Social Media and Mobile Apps for Weight Control: Mixed Methods Study
Authors: Nikolaou Charoula Konstantia , Tay Zoey , Leu Jodie , Rebello Salome Antonette , Te Morenga Lisa , Van Dam Rob M , Lean Michael Ernest John 
Published: June 2019

Background
Effective prevention at a young enough age is critical to halt the obesity epidemic. Mobile health (mHealth) apps would potentially reach large numbers at low-cost. While there is already a profusion of lifestyle apps, they are mostly non-evidence-based and evidently ineffective against rising obesity prevalence.

Objective
The aim of this study was to explore preferences and usage of lifestyle apps among young people in 6 countries.

Methods
A mixed methods study was conducted among young people aged 13 to 24 years residing in the United Kingdom, Belgium, Finland, Greece, Singapore, and New Zealand. Participants were recruited from Web advertisements on Facebook, asking for volunteers interested in mobile apps in general, not specific to lifestyle or health, to complete a short survey comprising 18 questions on demographics, weight gain, and mobile app preferences and then to join English-language online focus groups, which were held during 2017, in password-protected Web rooms, moderated by an experienced researcher. Descriptive statistics were carried out for the survey, and thematic analysis was applied to transcripts.

Results
A total of 2285 young people (610 adolescents aged 13-17 years and 1675 young adults aged 18-24 years) responded and completed the survey, with 72.0% (1645) reported being concerned about weight gain for themselves or friends. Later, 807 young people (376 adolescents and 431 young adults) were selected based on age and country to participate in 12 online focus groups, with 719 young people completing. Analysis revealed 4 main themes: (1) feelings toward personal weight; (2) perception of lifestyle apps and desired content for weight gain prevention; (3) social media apps, lifestyle apps, and motivation for downloading and retaining; and (4) data safety and data usage and confidentiality. Young people are interested in evidence-based advice in programs incorporating their preferences.

Conclusions
Young people are commonly, and consistently across 6 countries, concerned about weight gain and obesity and would welcome evidence-based mHealth programs, provided the views of young people themselves are incorporated in the program content.
Development, Depoliticisation, and Manggaraian Peasants’ Resistance in Western Flores
Authors: Haryanto Venansius 
Published: June 2019

This article explores how certain elements of society show resistance against the process of depoliticisation that works through development. Drawing on the case of peasants in Lembor, a regency in Western Flores, East Nusa Tenggara (NTT), this article argues that, by offering a so-called ‘alternative development’, civil society actors attempt to show their resistance against the process of depoliticisation that has been implemented through the rice monoculture farming system. To this end, the theories of depoliticisation and alternative development as resistance shall be used as analytical tools. Depoliticisation is defined in the literature as the process through which the regime of mainstream development relocates politico-economic questions in dealing with the problems of peasants, in this case those in Lembor. Meanwhile, the theory of alternative development will be used to frame the form of peasants’ resistance in Lembor. The ultimate end of this study is to restore power to political analysis. As such, this article seeks to conflate development and democracy in discussing citizens’ welfare.
THE IMPACTS OF STUTTERING SHIFTS TO THE TRANSLATION QUALITY OF THE ADVENTURE OF TINTIN COMICS
Authors: Prasojo Rudy 
Published: June 2019

This article aims to discuss how stuttering utterances are translated from English to Bahasa Indonesia. Data in the form of stuttering utterances spoken by Captain Haddock, a character in The Adventure of Tintin comic series, were collected to see how the translator decided to convert those utterances into Bahasa Indonesia. The method employed in this research is the qualitative-descriptive in which the data were taken from two sources(English and Bahasa Indonesia). The finding shows that there are three categories of stuttering initiator namely:Â intoxicated, emotions, and situations. Each category is classified based on its types, namely repetitions, hesitations, and fillers. In addition, the finding also shows that each type of stuttering was placed in a different concept on its target language named shifting. It can further be classified into preserved, altered, and omitted. Each of them affects the meaning and the message of stuttering utterances in the translation version. Finally, the statistic indicates that every type of shifting gives a significant impact to the translation quality.
Knowledge and Skills in Complex Assurance Engagements: The Case of XBRL
Authors: Debreceny Roger S. , Farewell Stephanie M. , Scarlata Audrey N. , Stone Dan N. 
Published: June 2019

ABSTRACT
What knowledge and skills (KSs) are necessary for complex Agreed-Upon Procedures (AUP) engagements, such as those that include eXtensible Business Reporting Language (XBRL) tagged data? This study contributes by investigating these issues in two studies: (1) a survey and (2) structured interviews of accounting professionals with XBRL expertise. Survey results suggest commonality in perceptions of the KSs needed in two knowledge categories, “Accounting and Financial Reporting” and “Undertaking AUP on XBRL Instance Documents,” and, variability in ratings of two categories: “XBRL technology” and “audit procedures.” Interview results indicate that knowledge of the U.S. GAAP Taxonomy is most important to AUP engagements followed by the nature of AUP engagements. The results suggest: (1) a need for clarification of XBRL-relevant KSs and (2) an important but unfilled role for universities and scholars in discerning, supporting, and developing the KSs needed to support complex assurance engagements.
The Cardiometabolic Risk Profile of Young Adults With Diabetes in the U.S.
Authors: Saydah Sharon H. , Siegel Karen R. , Imperatore Giuseppina , Mercado Carla , Gregg Edward W. 
Published: June 2019

OBJECTIVE
We examined young adults with and young adults without diabetes by using demographic data and cardiometabolic risk profiles and compared the risk profiles of younger versus older (aged ≥45 years) adults with diabetes.

RESEARCH DESIGN AND METHODS
Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2016. Diabetes was defined by self-report of health care provider diagnosis or by A1C levels of 6.5% or higher among those without a self-reported diagnosis. The cardiometabolic risk profile included adiposity, blood pressure, serum lipids, healthy eating, physical activity (PA), and exposure to tobacco smoke. Adjusted difference in difference was calculated as the difference among younger adults with and younger adults without diabetes minus the difference among older adults with and older adults without diabetes.

RESULTS
Adults with diabetes in both age-groups had higher levels of adiposity, hypertension, and cholesterol and lower levels of healthy eating and leisure-time PA. However, the differences in high cholesterol and adiposity by diabetes status were greater among young adults compared with older adults after adjustment for demographics and health insurance status. Elevated lipids were 9.6 percentage points higher (95% CI 4.6, 14.5) and obesity was 37.3 percentage points higher (95% CI 31.8, 42.7) among young adults with diabetes compared with those without diabetes than among older adults with diabetes compared with those without diabetes.

CONCLUSIONS
Young adults with diabetes have high rates of cardiometabolic risk factors, which can lead to an increased disease prevalence and mortality rate among these individuals as they age.
Pathomorphological studies on wild boars infected with Metastrongylus spp., Ascarops strongylina, and Macracanthorhynchus hirudinaceus
Authors: Panayotova-Pencheva Mariana , Todorova Katerina , Dakova Vassilena 
Published: June 2019

Abstract

Introduction: Pathomorphological changes in the lungs, stomach, and small intestines of wild boars infected with Metastrongylus spp., Ascarops strongylina, and Macracanthorhynchus hirudinaceus were investigated. Material and Methods: Dissection of 11 wild boars was performed, and parasitised organs were histologically investigated by common techniques. Results: Macroscopic lesions in the lungs infected with Metastrongyus spp. were seen within the apical parts of the large lobes, irregular in form, pale greyish in colour, and compact in consistency. The main pathohistological findings were: the presence of parasite forms, and lymphocytes and neutrophils in the lumen of bronchi and bronchioles, desquamation of the bronchial and bronchiolar epithelium, emphysema, thickening of alveolar septa, hyperaemia, alveolitis, infiltration of the interstitial tissue with giant cell, monocytes and eosinophils, and peribronchial and disseminated lymphoid hyperplasia. The principal observations accompanying infection with A. strongylina were inflammation and focal mucosal damage in the stomach, the latter clearly demarcated from the surrounding tissues. Severe injuries in the place of attachment of M. hirudinaceus to the wall of the small intestine were seen. Intestinal villi, underlying mucosa, and submucosa were destroyed, and an intense inflammatory reaction was present. Conclusion: The histopathological lesions showed wide diversity, varying from mild to severe; but none of them were lethal.
STUDI PERBANDINGAN KONSENTRASI KLOROFIL-A DI SEMENANJUNG BLAMBANGAN KABUPATEN BANYUWANGI MENGGUNAKAN DATA CITRA SATELIT AQUA MODIS
Authors: Zainab Siti , Wibisana Hendrata , Casita Cintantya Budi 
Published: June 2019

<p>Pemetaan kandungan klorofil-a di pesisir pantai banyak dilakukan dengan tujuan untuk mendapatkan gambaran tingkat kesuburan dari lingkungan perairan yang dimaksud. Tingkat kesuburan yang diharapkan dapat memberikan gambaran populasi dari perikanan tangkap yang dibutuhkan oleh masyarakat pesisir dalam meningkatkan kesejahteraan hidupnya. Penginderaan jauh sebagai salah satu teknologi yang baru telah memberikan banyak manfaat untuk pendeteksian dan pemetaan konsentrasi klorofil-a skala global. Tujuan dari penelitian ini untuk mendapatkan gambaran kandungan klorofil-a pada dua area yang berbeda yaitu di daerah Semenanjung Blambangan dan daerah Teluk Blambangan. Metode yang dikembangkan dari penelitian ini adalah penggunaan algoritma penginderaan jauh dan teknik regresi guna mendapatkan model matematis yang optimal untuk digunakan dalam peramalan kandungan klorofil-a di masa yang akan datang. Dari penelitian ini diperoleh model matematis yang paling sesuai untuk kondisi Teluk Blambangan yaitu pada panjang gelombang sinar hijau dengan nilai 531 nanometer (nm), di mana korelasi yang terbesar adalah Chlor-a = 21228*(Rrs_531)-42,371 dengan nilai R2 sebesar 0,7951 yang didapatkan dari panjang gelombang sinar hijau yaitu Rrs_531 dari citra satelit Aqua Modis Level-2. Fenomena ini dapat disimpulkan bahwa kandungan klorofil-a di semenanjung Blambangan pada bulan Agustus 2017 cukup signifikan di mana diperoleh rata-rata konsentrasi dari klorofil-a sebesar 18,45 ppt(mg/ m³) sehingga dapat diprediksikan bahwa populasi ikan yang ada di perairan tersebut juga meningkat pada bulan tersebut. Hasil akhir yang didapatkan berupa peta tematis kandungan klorofil-a untuk algoritma model linier, di samping itu persamaan matematis yang dihasilkan diharapkan dapat digunakan oleh para peneliti lainnya untuk mendapatkan model yang lebih akurat yang dapat menggambarkan kondisi riil di lapangan.</p><p> </p>
Acidentes com motocicletas na Bahia: análise de uma década de internações hospitalares
Authors: Faleiro Thiago Batista , Ladeia Augusto Morgan Alves , Júnior Antônio Manuel Pinto , Schulz Renata da Silva , Rosário Davi Araújo Veiga , Franco Bruno Adelmo Ferreira Mendes , Meirelles Alexandre Vasconcelos de , Daltro Gildásio , Spínola Ademario Galvão 
Published: June 2019

Objetivo: Analisar as internações por acidentes com motocicletas no sistema público de saúde da Bahia no período entre 2008 e 2017. Métodos: Estudo transversal, descritivo e retrospectivo das internações por acidentes com motocicletas na rede pública de saúde da Bahia. Os dados foram obtidos do Sistema de Informações Hospitalares do SUS (SIH/SUS) do Ministério da Saúde. Resultados: Entre os anos de 2008 e 2017 foram realizadas 45714 internações decorrentes do grupo de causas do CID-10 V20-V29 (motociclista traumatizado em acidente de transporte). O tempo médio de internação foi de 31,12 dias e o custo total foi de aproximadamente 207 milhões e 798 mil reais. A faixa etária mais acometida foi a de 20 a 39 anos de idade representando 58,53% do total e o sexo masculino representou 85,12% das vítimas. A taxa de mortalidade foi em média de 9,54% refletindo a gravidade dos acidentes. Conclusão: O estudo mostra a gravidade dos acidentes de motocicletas atendidos no Sistema Único de Saúde na Bahia comprometendo principalmente homens jovens, em idade produtiva e com alto custo e taxa de mortalidade. Esses dados reforçam a necessidade de medidas institucionais para redução do número de acidentes e novos estudos são importantes para determinar as sequelas que eventualmente acometem os sobreviventes.
Inhibitive Potential of Prosopis Africana on Corrosion of Low Carbon Steel in 1M Hydrochloric Acid Medium
Authors: SHUAIB-BABATA YUSUF LANRE , IBRAHIM KOBE HASSAN , AMBALI OWOLABI IBRAHIM , YAHYA ABOLORE RAHEEM , AJAO SULEIMAN KABIRU , AREMU ISHAQ NA'ALLAH , PELUMI ABIBAT ATINUKE 
Published: June 2019

Recently, there is quest for the use of inexpensive, non-toxic, non-biodegradable, readily available and environmentally acceptable corrosion inhibitor. Studies have shown that these properties could be achieved through the use of plants as inhibitor. Inhibiting effect of Prosopis Africana (Iron Tree) seed extracts were assessed on a sample of low carbon steel in 1M HCl with varying proportion of the seed extract using gravimetric, Tafel polarization and gasometrical measurement techniques. The results show that weight loss/corrosion rate decreases with increase in the extracts’ concentrations. Good inhibiting efficiency of Prosopis Africana extracts with optimum inhibiting efficiency of 97.7% at 1.0 g/l after 120 hours exposure in gravimetric measurement was attained. TAFEL polarization results revealed that the Prosopis Africana extract shows that the corrosion current density decreases with the increase in the concentration of the extract. The extract is found suitable as green inhibitor for corrosion of low carbon steel in the studied medium.
Combination prevention and HIV: a cross-sectional community survey of gay and bisexual men in London, October to December 2016
Authors: Logan Louise , Fakoya Ibidun , Howarth Alison , Murphy Gary , Johnson Anne M , Rodger Alison J , Burns Fiona , Nardone Anthony 
Published: June 2019

Background
Men who have sex with men (MSM) are at risk of HIV and are an important population to monitor and ameliorate combination prevention efforts.

Aim
To estimate HIV prevalence and identify factors associated with frequent HIV testing (≥ 2 HIV tests in the last year) and pre-exposure prophylaxis (PrEP) use among MSM in London.

Methods
For this cross-sectional study, MSM recruited from 22 social venues provided oral-fluid samples for anonymous HIV antibody (Ab) testing and completed a questionnaire. Factors associated with frequent HIV testing and PrEP use were identified through logistic regression.

Results
Of 767 men recruited, 545 provided an eligible oral specimen. Among these, 38 MSM (7.0%) were anti-HIV positive including five (13.2%; 5/38) who reported their status as negative. Condomless anal sex within the previous 3 months was reported by 60.1% (412/685) men. Frequent HIV testing was associated with, in the past year, a reported sexually transmitted infection (adjusted odds ratio (AOR): 5.05; 95% confidence interval (CI): 2.66–9.58) or ≥ 2 casual condomless partners (AOR 2–4 partners: 3.65 (95% CI: 1.87–7.10); AOR 5–10 partners: 3.34 (95% CI: 1.32–8.49). Age ≥ 35 years was related to less frequent HIV testing (AOR 35–44 years: 0.34 (95% CI: 0.16–0.72); AOR ≥ 45 years: 0.29 (95% CI: 0.12–0.69). PrEP use in the past year was reported by 6.2% (46/744) of MSM and associated with ≥ 2 casual condomless sex partners (AOR: 2.86; 95% CI: 1.17–6.98) or chemsex (AOR: 2.31; 95% CI: 1.09–4.91).

Conclusion
This bio-behavioural study of MSM found high rates of behaviours associated with increased risk of HIV transmission. Combination prevention, including frequent HIV testing and use of PrEP, remains crucial in London.