bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of China’s outward foreign direct investment in the Belt & Road economies
Authors: Shahriar Saleh , Kea Sokvibol , Qian Lu 
Published: September 2019

PurposeThe purpose of this paper is to investigate the major determinants of China’s outward foreign direct investment (OFDI) in the economies along the “Belt & Road” Initiative (BRI afterward). China works on to advance the agenda of the BRI both at home and abroad. The BRI is set up to promote connectivity in five key areas: policy coordination, infrastructure connectivity, trade facilitation, financial cooperation and people-to-people contacts.Design/methodology/approachThe existing literature is inconclusive with regards to the motives, patterns and determinants of the Chinese OFDI. The authors are, therefore, motivated to undertake this study to shed some new light on the influencing factors of the Chinese OFDI. The authors have made a unique data set that consists of China and its 64 partnering countries of the BRI over a time period of 12 years spanning from 2004 to 2015. This time period is chosen on the chief consideration of data availability. The authors have a balanced panel, and applied the gravity model in line with the theoretical arguments and econometric developments.FindingsThe paper assumes that China’s OFDI along the BRI was a function of gross domestic product (GDP), income per capita, distance and WTO. The findings showed that GDP, per capita income and distance were the key determinants of the OFDI. China’s entry into the WTO did not strongly affect the OFDI. China maintained a tradition of historical relationships along the BRI economies. After all, China is relocating its investment resources in line with the consideration of its partnering countries’ economic size, cross-border distance and per capita income.Originality/valueThis study is the first of its kinds to analyze the determinants of OFDI by means of gravity model. The authors have covered all the countries along the BRI. Hence, this paper aims to make a substantial contribution to the literature, both from a scientific and a policy perspective.
Leader’s integrity and interpersonal deviance
Authors: Erkutlu Hakan , Chafra Jamel 
Published: September 2019

PurposeThe purpose of this paper is to posit that leader’s integrity decreases employee’s interpersonal deviance by increasing moral efficacy in the workplace. Specifically, the authors propose that perceptions of moral efficacy serve as a mechanism through which leader’s integrity affects workplace deviance. The authors further argue that the modeled relationships are moderated by moral identity.Design/methodology/approachData were collected from ten universities in Turkey. The sample included 693 randomly chosen faculty members along with their department chairs.FindingsThe results of this study supported the negative effect of leader integrity on employee’s interpersonal deviance as well as the mediating effect of moral efficacy. Moreover, when the level of moral identity is high, the relationship between leader integrity and interpersonal deviance is strong, whereas the relationship is weak when the level of moral identity is low.Practical implicationsThis study’s findings indicate that higher education administrators should be cautious in treating their subordinates, as this will lead to a favorable interpersonal relationship, which in turn will reduce the interpersonal deviance of the subordinate. In addition, the buffering role of the moral identity should be paid more attention, particularly to people with low moral efficacy and high interpersonal deviance.Originality/valueThis study contributes to workplace deviance literature by revealing the relation between leader integrity and interpersonal deviance. Furthermore, it offers practical assistance to higher education employees and their leaders concerned with building trust, increasing the relationship between leaders and employees and reducing the interpersonal deviation.
Factors influencing acceptance of augmented reality in retail: insights from thematic analysis
Authors: Perannagari Krishna Teja , Chakrabarti Somnath 
Published: September 2019

Purpose
The purpose of this paper is to examine the impact of augmented reality (AR) on retailing by conducting thematic analysis on variables studied in the existing literature.

Design/methodology/approach
The data set includes 232 variables studied in 35 research papers, collected using well-defined search and inclusion criteria. Thematic analysis is used to identify patterns in the data set.

Findings
The eight themes emerging from the analysis are arranged in the form of a conceptual framework to model the decision-making process of users. The position of themes in the model is determined by the most dominant variable type in the theme and by employing the technology acceptance model as the reference paradigm.

Research limitations/implications
The current review contributes to the advancement of literature by setting a research agenda for scholars working in the field of consumer behavior and human–computer interaction. Future research should improve the generalizability of the research by replicating the method and testing the conceptual framework on other immersive technologies.

Practical implications
Marketers should incorporate AR technology into their experiential marketing strategies. Since integrating and managing AR technology requires expertise, organizations are advised to make use of existing toolkits or collaborate with technology companies to develop their offerings.

Originality/value
To maintain the uniqueness of the current study from other papers focusing on existing research done in this area, this review considers only studies using statistical techniques to study consumer behavior pertaining to AR in retail. The study uses an unconventional method for identifying patterns in the existing literature by employing theories and frameworks as the basis of classification.
Owned-by and made-in cues
Authors: Zolfagharian Mohammadali , Saldivar Roberto , Williams Jerome D. 
Published: September 2019

PurposeThe purpose of this paper is to examine the cognitive and affective dimensions of COO and the owned-by/made-in cue combinations in first-generation immigrant markets.Design/methodology/approachThe cognitive and affective dimensions were manipulated in a scenario-based experiment administered on 261 Mexican Americans in three product categories.FindingsThe cognitive and affective dimensions each have a distinct impact. When the two dimensions combine, the effect is stronger within the specialty product category, followed by the shopping product category, and, to a lesser extent, in the convenience product category.Research limitations/implicationsThe cognitive dimension was represented by the country’s degree of political, economic and technological development, whereas the affective dimension was traced by examining immigrants who identify with the emotional and symbolic meanings associated with countries involved in the country of origin (COO) message.Practical implicationsManagers should pursue emerging COO research whose concepts and designs are congruent with today’s global consumer culture. The authors find support for the stand-alone effects of made-in and owned-by COO cues, as well as the effects of the cognitive and affective dimensions of COO. When COO messages combine both made-in and owned-by cues, the cognitive and affective dimensions may work synergistically, depending on the product category.Originality/valueThis study adds to the nascent literature that recognizes the multiplicity of consumer identities, and bridges the gulf between the conventional COO research and the increasingly multicultural nature of the marketplace.
Do social capital and relationship quality matter to the key account management effectiveness?
Authors: Badawi Nada Saleh , Battor Moustafa 
Published: September 2019

PurposeThe purpose of this paper is to investigate the influence of social capital and relationship quality on key account management (KAM) effectiveness.Design/methodology/approachBased on the literature, the authors designed a framework that links social capital, relationship quality and KAM effectiveness. Data were collected through a self-administered questionnaire. Using data from a sample of 172 business-to-business supplier firms, the authors examined this model.FindingsThe research results provide empirical support to the importance of relational aspects of KAM by showing how the relational aspects of relationship quality and social capital influence the effectiveness of the supplier-key account relationship.Originality/valueThe authors add to the literature on relational KAM by integrating theoretical perspectives on social capital, relationship quality and KAM. They develop a model that investigates the antecedents of the effectiveness of supplier–key account relationships from a relational perspective. The study explains the relationships between six constructs representing social capital (ability, benevolence, integrity, flexibility, information exchange and solidarity) and three constructs representing relationship quality (trust, satisfaction and relationship atmosphere), together with the relationships between these three constructs of relationship quality and KAM effectiveness.
To B or not to B: Etsy’s decision whether to re-incorporate as a public benefit corporation and maintain its B Lab certification
Authors: Lingenfelter Gabriele , Cohen Ronnie 
Published: September 2019

Theoretical basis
As the regulatory system begins to recognize the role of social responsibility reporting, reliable disclosure measures will be required. Issues of transparency, reliability and assurance are likely to arise as securities regulators consider whether and how to require disclosure of non-financial information. Various reporting models are presented in the case to illustrate different ways that these issues can be addressed by privately held and publicly traded corporations.

Research methodology
The case uses the company, Etsy, Inc., which has established itself as a publicly traded, socially responsible corporation. Etsy must decide whether it will re-incorporate as a benefit corporation in order to maintain its B Lab certification. This decision introduces students to the various measures of corporate social responsibility, the interests of the stakeholders of a corporation and the regulatory environment in which socially responsible, publicly traded corporations operate. The case uses only publicly available information.

Case overview/synopsis
This teaching case addresses the decision faced by Etsy, Inc. when it became a publicly traded corporation. In order to maintain its certification as a socially responsible corporation by B Lab, it would have to re-incorporate as a Delaware Benefit Corporation. In making this decision, the company had to consider various measures used for corporate social responsibility reporting and transparency and how these might affect Etsy’s stakeholders.

Complexity academic level
Undergraduate or masters level case that could be used in a business law, commercial law, legal environment or auditing course.
Cutaneous tuberculosis in Rio de Janeiro, Brazil: description of a series of 75 cases
Authors: Mann Danielle , Sant’Anna Flavia M. , Schmaltz Carolina A. S. , Rolla Valeria , Freitas Dayvison F. S. , Lyra Marcelo R. , Sampaio Felipe M. S. , do Valle Antonio C. F. , Lourenço Maria C. S , Quintella Leonardo P. , Teichner Tullia C. , Cavalcante Solange C. , Galhardo Maria C. G. 
Published: September 2019

AbstractBackgroundBrazil is one of the highest tuberculosis (TB) burden countries of the world. Cutaneous tuberculosis (CTB) is a rare form of extrapulmonary manifestation of tuberculosis. This study aimed to describe the clinico‐evolutive, laboratory and therapeutic aspects of CTB cases among patients from a cohort with TB in Rio de Janeiro, Brazil.MethodsCases of diagnosed CTB with microbiologic confirmation or clinical response to anti‐tuberculous treatment associated with positive smear or histopathological findings between the years 2000 and 2016 were selected.ResultsSeventy‐five patients with CTB were included, most were women (58.7%) with a median age of 42 years. CTB diagnosis was based on culture in only 42.7% of the cases. Scrofuloderma represented 50.7% of the cases, followed by erythema induratum of Bazin (EIB) (18.7%), tuberculous gumma (13.3%), lupus vulgaris (8%), TB verrucosa cutis (4%), orificial TB (2.7%) and associated forms (2.7%). Other TB presentations were pulmonary (22.7%), mammary (6.6%) and osteoarticular (4%). All patients who completed the treatment (97.3%) had their lesions healed. Only two patients (2.6%) needed to change the therapy due to adverse reactions. Fifty percent of EIB patients presented recurrence.ConclusionsThese data highlight the diversity of CTB presentations and the importance of the skin to assist in early identification and treatment of TB. More studies are necessary to improve the knowledge on EIB for a better approach towards these patients, mainly in cases of recurrence.
Subcellular NAMPT‐mediated NAD+ salvage pathways and their roles in bioenergetics and neuronal protection after ischemic injury
Authors: Wang Xiaowan , Zhang Zhe , Zhang Nannan , Li Hailong , Zhang Li , Baines Christopher P. , Ding Shinghua 
Published: September 2019

AbstractNAD+ is a cofactor required for glycolysis, tricarboxylic acid cycle, and complex I enzymatic reaction. In mammalian cells, NAD+ is predominantly synthesized through the salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate‐limiting enzyme. Previously, we demonstrated that NAMPT exerts a neuroprotective effect in ischemia through the suppression of mitochondrial dysfunction. Mammalian cells maintain distinct NAD+ pools in the cytosol, mitochondria, and nuclei. However, it is unknown whether mitochondria have an intact machinery for NAD+ salvage, and if so, whether it plays a dominant role in bioenergetics, mitochondrial function, and neuronal protection after ischemia. Here, using mouse primary cortical neuron and cortical tissue preparations, and multiple technologies including cytosolic and mitochondrial subfractionation, viral over‐expression of transgenes, molecular biology, and confocal microscopy, we provided compelling evidence that neuronal mitochondria possess an intact machinery of NAMPT‐mediated NAD+ salvage pathway, and that NAMPT and nicotinamide mononucleotide adenylyltransferase 3 (NMNAT3) are localized in the mitochondrial matrix. By knocking down NMNAT1‐3 and NAMPT with siRNA, we found that NMNAT3 has a larger effect on basal and ATP production‐related mitochondrial respiration than NMNAT1‐2 in primary cultured neurons, while NMNAT1‐2 have a larger effect on glycolytic flux than NMNAT3. Using an oxygen glucose deprivation model, we found that mitochondrial, cytoplasmic, and non‐subcellular compartmental over‐expressions of NAMPT have a comparable effect on neuronal protection and suppression of apoptosis‐inducing factor translocation. The current study provides novel insights into the roles of subcellular compartmental NAD+ salvage pathways in NAD+ homeostasis, bioenergetics, and neuronal protection in ischemic conditions.
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Inhibition of transglutaminase activity in periodontitis rescues periodontal ligament collagen content and architecture
Authors: Moore Rosset Emilie , Trombetta‐eSilva Jessica , Hepfer Glenn , Chen Peng , Yao Hai , Bradshaw Amy D. 
Published: September 2019

AbstractBackground and objectivePeriodontal disease (PD) afflicts approximately 50% of the population in the United States and is characterized by chronic inflammation of the periodontium that can lead to loss of the periodontal ligament through collagen degradation, loss of alveolar bone, and to eventual tooth loss. Previous studies have implicated transglutaminase (TG) activity in promoting thin collagen I fiber morphology and decreased mechanical strength in homeostatic PDL. The aim of this study was to determine whether TG activity influenced collagen assembly in PDL in the setting of periodontal disease.Material and methodsA ligature model was used to induce clinically relevant PD in mice. Mice with ligature were assessed at 5 and 14 days to determine PDL collagen morphology, transglutaminase (TG) activity, and bone loss. The effects of inhibition of TG on PDL were assessed by immunohistochemistry and second‐harmonic generation (SHG) to visualize collagen fibers in native tissue.ResultsLigature placement around the 2nd molar resulted in significant bone loss and a decrease in total collagen content after 5 days of ligature placement. A significant increase in thin over thick fibers was also demonstrated in mice with ligature at 5 days associated with apparent increases in immunoreactivity for TG2 and for TG‐mediated N‐ε‐γ‐glutamyl cross‐links in PDL. Inhibition of TG activity increased total collagen and thick collagen fiber content over vehicle control in mice with ligature for 5 days. SHG of PDL was used to visualize and quantify the effects of TG inhibition on enhanced collagen fiber organization in unfixed control and diseased PDL.ConclusionThese studies support a role of TG in regulating collagen fiber assembly and suggest that strategies to inhibit TG activity in disease might contribute to restoration of PDL tissue integrity.
Are submarine and subaerial drainages morphologically distinct?
Authors: Dobbs Stephen C. , McHargue Tim , Malkowski Matthew A. , Gooley Jared T. , Jaikla Chayawan , White Colin J. , Hilley George E. 
Published: September 2019

AbstractThe qualitative resemblance between terrestrial and submarine branched valley networks has led to speculation that common underlying processes control their formation. However, quantitative comparisons have been impeded by methodological limitations and coarse resolution in marine systems. We analyze channel concavity and steepness indices of 23 terrestrial and 29 submarine catchments to determine whether their profile morphologies are distinct. Statistical comparisons of these quantities demonstrate that concavity indices in submarine systems are, in general, lower than in subaerial systems, and that submarine tributaries are steeper than their associated mainstem. These differences may reflect distinct drainage formation mechanisms and dynamics of submarine sediment gravity flows as compared to overland flow processes.
Biomarker evidence for nitrogen-fixing cyanobacterial blooms in a brackish surface layer in the Nile River plume during sapropel deposition
Authors: Bale Nicole J. , Hennekam Rick , Hopmans Ellen C. , Dorhout Denise , Reichart Gert-Jan , van der Meer Marcel , Villareal Tracy A. , Sinninghe Damsté Jaap S. , Schouten Stefan 
Published: September 2019

Abstract
Sapropels are organic-rich sediment layers deposited in the eastern Mediterranean Sea during precession minima, resulting from an increase in export productivity and/or preservation. Increased freshwater delivery from the African continent resulted in stratification, causing deepwater anoxia, while nutrient input stimulated productivity, presumably at the deep chlorophyll maximum. Previous studies have suggested that during sapropel deposition, nitrogen fixation was widespread in the highly stratified surface waters, and that cyanobacteria symbiotic with diatoms (diatom-diazotroph associations, DDAs) were responsible. Here we analyzed sapropel S5 sediments for heterocyst glycolipids (HGs) from three locations in the eastern Mediterranean. HG biomarkers can differentiate between those heterocystous cyanobacteria that are free living (found predominately in freshwater or brackish environments) and those that are from DDAs (found in marine settings). In our primary core, from a location which would have been influenced by the Nile River outflow, we detected a HG with a pentose (C5) head group specific for DDAs. However, HGs with a hexose (C6) head group, specific to free-living cyanobacteria, were present in substantially (up to 60×) higher concentration. These data suggest that at our study location, free-living cyanobacteria were the dominant diazotrophs, rather than DDAs. The C6 HGs increased substantially at the onset of sapropel S5 deposition, suggesting that substantial seasonal cyanobacterial blooms were associated with a brackish surface layer flowing from the Nile into the eastern Mediterranean. Two additional S5 sapropels were analyzed, one also from the Nile delta region and one from the region between Libya and southwestern Crete. Overall, comparison of the HG distribution in the three S5 sapropels provides evidence that all three locations were initially influenced by surface salinities that were sufficiently low to support free-living heterocystous cyanobacteria. While free-living heterocystous cyanobacteria continued to outnumber DDAs during sapropel deposition at the two Nile-influenced sites, DDAs, indicators of persistent marine salinities, were the dominant diazotrophs in the upper part of the sapropel at the more westerly site. These results indicate that N2 fixation by free-living cyanobacteria offers an important additional mechanism to stimulate productivity in regions with strong river discharge during sapropel deposition.
A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
Authors: Yang Zhenyu , Wang Dan , Johnson James K. , Pascal Laura E. , Takubo Keita , Avula Raghunandan , Chakka Anish Bhaswanth , Zhou Jianhua , Chen Wei , Zhong Mingming , Song Qiong , Ding Hui , Wu Zeyu , Chandran Uma R. , Maskrey Taber S. , Nelson Joel B. , Wipf Peter , Wang Zhou 
Published: September 2019

AbstractReactivation of androgen receptor (AR) appears to be the major mechanism driving the resistance of castration-resistant prostate cancer (CRPC) to second-generation antiandrogens and involves AR overexpression, AR mutation, and/or expression of AR splice variants lacking ligand-binding domain. There is a need for novel small molecules targeting AR, particularly those also targeting AR splice variants such as ARv7. A high-throughput/high-content screen was previously reported that led to the discovery of a novel lead compound, 2-(((3,5-dimethylisoxazol-4-yl)methyl)thio)-1-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethan-1-one (IMTPPE), capable of inhibiting nuclear AR level and activity in CRPC cells, including those resistant to enzalutamide. A novel analogue of IMTPPE, JJ-450, has been investigated with evidence for its direct and specific inhibition of AR transcriptional activity via a pulldown assay and RNA-sequencing analysis, PSA-based luciferase, qPCR, and chromatin immunoprecipitation assays, and xenograft tumor model 22Rv1. JJ-450 blocks AR recruitment to androgen-responsive elements and suppresses AR target gene expression. JJ-450 also inhibits ARv7 transcriptional activity and its target gene expression. Importantly, JJ-450 suppresses the growth of CRPC tumor xenografts, including ARv7-expressing 22Rv1. Collectively, these findings suggest JJ-450 represents a new class of AR antagonists with therapeutic potential for CRPC, including those resistant to enzalutamide.