bluuebunny/crossref_metadata_2025_split huggingface dataset:
(056) VAS DEFERENS TO RETE TESTIS ANASTOMOSIS: STEP-BY-STEP MICROSURGICAL RECONSTRUCTION
Authors: Savio LF , Mesquita F , Campos L , Miller D , Codrington J , White JT , Muthigi A , Ramasamy R 
Published: December 2024

Abstract

Introduction
This video aims to present an in-depth, step-by-step tutorial on microsurgical reconstruction for obstructive azoospermia, featuring a distinctive case involving anastomosis from vas deferens to rete testis. The video endeavors to disseminate expertise, methodologies, and perspectives that can be advantageous to individuals grappling with obstructive azoospermia, providing a significant contribution to the progress of reproductive medicine and the augmentation of existing treatment alternatives.

Objective
The primary aim of this endeavor is to offer thorough and practical insights for healthcare professionals and researchers within the realm of reproductive medicine.

Methods
Surgical footage was recorded using the ORBEYE 4 K 3D Orbital Camera System by Olympus America, with patient consent acquired for research purposes. Additionally, a retrospective examination of patient records was undertaken to compile relevant medical histories.

Results
This video furnishes an exhaustive guide to microsurgical reconstruction for obstructive azoospermia, encompassing a distinctive instance of anastomosis from vas deferens to rete testis. State-of-the-art technology, such as the ORBEYE 4 K 3D Orbital Camera, heightens procedural transparency, accentuating the significance of advanced instrumentation. The ethical underpinning is emphasized by obtaining patient consent for footage utilization, and a retrospective chart review augments the repository of valuable patient data. This comprehensive approach serves as an invaluable reservoir of knowledge for medical professionals and underscores excellence in clinical and ethical healthcare research.

Conclusions
Anastomosis from vas deferens to rete testis emerges as a viable surgical reconstruction alternative for obstructive azoospermia, particularly when confronted with non-dilated tubules within the epididymis.

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(059) DEVELOPMENT OF AN ANIMAL MODEL TO DEMONSTRATE THE EFFECTIVENESS OF COLLAGEN-FLEECE (TACHOSIL) PATCHES FOR REPAIRING TUNICA ALBUGINEA DEFECTS IN RATS
Authors: Seyam R , Mandourah H , Al-Hussain T , Kattan S , Altaweel W 
Published: December 2024

Abstract

Introduction
A penile tunica defect may arise during penile prosthesis surgery or reconstruction of the penis in patients with Peyronie’s disease. Collagen fleece (TachoSil) was recently reported in penile surgery to cover the tunica defect with reported clinical success. However, there is no animal model to study the histological and hemodynamic outcomes of these grafts in the penis.

Objective
We demonstrate TachoSil patching in a murine animal model. The rat is an excellent model for studying histopathology and the physiology of erection after Tachosil patching.

Methods
Seven adult male Sprague Dawley rats were used. All procedures were carried out under general inhalation anesthesia. The penis was degloved through a circumferential subcoronal incision. A longitudinal 1x10 mm defect was created at the base of the lateral aspect of the penis. A TachoSil patch (Takeda, Japan) was applied to the defect. The penile skin covering is restored and fixed with interrupted 5-6 zero absorbable sutures.

Results
The video demonstrates how to create a tunica albuginea defect and patch it with TachoSil. At the surgery, the rats weighed 390 gm (SD 33.8). All animals survived to the endpoint of two months.

Conclusions
The rat model for TachoSil penile patching is feasible and robust. It permits evaluation of the histological and physiological changes that may occur after surgery. The animal model may be adapted to different short-and long-term endpoints, variable tunica albuginea defect size, and to compare Tachosil to other grafting materials.

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(081) FEMALE SEXUAL DYSFUNCTION AFTER RADICAL CYSTECTOMY FOR BLADDER CANCER: A SINGLE CENTRE EXPERIENCE
Authors: Tran V , Attwell-Heap A 
Published: December 2024

Abstract

Introduction
Radical cystectomy (RC) for bladder cancer significantly impacts sexual function in both men and women. While post-operative erectile dysfunction is thoroughly addressed in men, there is a glaring lack of attention directed towards female sexual function and organ preservation. Current literature regarding functional outcomes in females after RC demonstrates significant heterogeneity, lack of standardized reporting, and poor discussions surrounding the impact of different surgical approaches on sexual function, such as organ-sparing surgery or vaginal reconstruction. In particular, orthotopic neobladder (ON) as a method for urinary diversion is associated with improved sexual and urinary function after RC.

Objective
We aim to study trends in the rate of females undergoing RC at our institution, and explore the extent of counselling surrounding surgical approach and impact on sexual function.

Methods
A retrospective chart review was performed of all female patients who underwent RC our institution in the last 5 years. Data was collected for patient demographics, histopathology, and documented discussions in medical records regarding surgical approach and sexual function pre- and post-operatively.

Results
From 2019 to May 2024, there were 44 patients who underwent radical cystectomy at our institution for bladder cancer, with females comprising 11 (25%) of cases. Among females, the median age was 67 years old. Based on histopathology alone, ON would have been a reasonable consideration for urinary diversion in all women. There was no documentation of discussions surrounding urinary diversion approaches, organ sparing, or sexual function pre- and post-operatively.

Conclusions
Given increasing awareness surrounding the importance of sexual function, this highlights an important area of oncosexology that remains inadequately addressed in clinical practice. At our institution, we are moving to introducing pre-operative functional assessments and counselling regarding sexual function using a multidisciplinary approach to guide the shared decision-making process prior to RC.

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(095) GRIEF AND SEXUAL INTIMACY: EXPLORING THERAPISTS’ VIEWS OF BEREAVED CLIENTS
Authors: Pascoal PM , Jones S , Albuquerque S 
Published: December 2024

Abstract

Introduction
The interaction between sexual intimacy and grief remains unexplored despite its potential to offer valuable insights into how individuals, couples, and society perspectives shape bereaved individuals’ sexual intimacy.

Objective
Through semi-structured interviews with ten clinical psychologists and psychotherapists specialized in grief therapy, this study explores the impact of grief on sexual intimacy, the challenges faced by bereaved individuals, and the role of sexual intimacy in the grieving process. The study also investigates therapists’ approaches to addressing sexual intimacy within grief therapy sessions.

Methods
Semi-structured interviews with licensed clinical psychologists specialized in Grief were conducted and analyzed using Grounded Theory framework.

Results
Findings reveal that grief often disrupts sexual intimacy, affecting individuals’ ability to engage emotionally and physically with their partners. Factors such as secondary loss, emotional availability, traumatic experiences, and the nature of the loss contribute to difficulties in resuming sexual intimacy. Nevertheless, the helpful role of sexual intimacy in grief was also highlighted. Therapists note the significance of communication, mutual empathy, and understanding in overcoming these challenges, advocating for therapy to address these issues comprehensively. Moreover, therapist-related, client-related, and shared factors hindering the exploration of sexual intimacy in grief therapy were identified. Strategies for managing these challenges include normalizing discussions around sexual intimacy and death, integrating systemic approaches into therapy, and providing training in sexuality or sexual therapy for grief therapists.

Conclusions
Overall, this study underscores the importance of recognizing and addressing the interplay between sexual intimacy and grief to support bereaved individuals effectively. Insights from therapists shed light on potential avenues for enhancing clinical interventions and fostering awareness of the complex dynamics surrounding bereavement and sexuality.

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(104) REDUCING THE GRAFTING AREA IN PEYRONIE’S DISEASE: INITIAL RESULTS OF THE IGRAFTER TECHNIQUE IN THE UNITED STATES
Authors: Lopes Cancado Machado B , Kuykendall K , Smith A , Puente C , Dietrich G 
Published: December 2024

Abstract

Introduction
Erectile dysfunction (ED) is commonly associated with plaque incision and graft techniques (PIG) for the treatment of severe Peyronie’s disease (curvatures ≥60°), and graft size is one of the factors that correlate with postoperative development of ED. The iGrafter technique, which reduces the total grafting area by approximately one-half compared to the Double-Y technique, could prevent the progression of ED postoperatively. In this study, we aimed to determine whether patients with severe Peyronie’s disease who underwent surgery with the iGrafter technique developed ED and sexual dissatisfaction.

Objective
Evaluate the erection function after penile curvature correction using iGrafter in a single center.

Methods
This retrospective study included 8 patients between the ages of 49 and 69 (mean: 59.5 ± 6.63) who underwent surgery for penile curvature correction. The surgery was performed by the same surgeon at the University of Arkansas for Medical Sciences between August 2017 and December 2023, and the surgeon used the iGrafter technique. Those with an inflatable penile prosthesis were excluded. Erectile function and intercourse satisfaction were evaluated preoperatively and postoperatively via international index of erectile function (IIEF-5) questionnaires obtained from chart reviews and telephone interviews.

Results
Follow-up was available for 6 (75%) of the 8 patients. The mean preoperative IIEF-5 score was 18.75 ± 7.5, and the mean postoperative IIEF-5 score was 21.75 ± 3.3, with an average follow-up of 1.5 years. No significant difference was observed between preoperative and postoperative IIEF-5 scores (P = 0.52) (Table 1). Eighty percent of patients reported satisfaction with the procedure, and all would opt for the procedure again.

Conclusions
The size of the grafting area contributes to postoperative ED in patients with severe Peyronie’s disease who undergo surgical correction by PIG. The iGrafter technique yields promising outcomes by reducing the grafting area by one-half when compared to the Double-Y technique. Our series showed no significant long-term declines in IIEF-5, consistent with high patient sexual satisfaction. Thus, our preliminary study revealed that patients undergoing surgery utilizing the iGrafter technique for severe Peyronie’s disease experienced no adverse effects on erectile function in the long-term postoperative phase compared to the preoperative period. Although current data is limited by a small sample size, our ongoing multicenter study aims to further validate these findings.

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(144) PREVALENCE OF FEMALE SEXUAL DYSFUNCTION IN A GROUP OF ARGENTINE WOMEN
Authors: Valente S , Gomez Cherey F , Leyton E , Bolognessi V , Soloa P , Ortiz J , Maldonado V 
Published: December 2024

Abstract

Introduction
Sexuality lived satisfactorily is essential for the development of a good quality of life and the preservation of health. Changes and difficulties in the dynamics of sexual experiences can cause different problems in sexual activity until reaching sexual dysfunctions. Health professionals should be attentive to the sexuality of our patients, since we could identify situations of this nature early to avoid recurring health problems and with an appropriate referral to a specialist, provide greater comfort in their quality of life.

Objective
To evaluate the domains of the Female Sexual Function Index (FSFI) in patients &gt;45 years old and those consulting for vulvar symptoms (VS) versus control.

Methods
The mean age was 42.1 (±13.7) years, 42.4% were &gt; 45 years old, 32.6% (47/144) were menopausal, 41% consulted for VS. FSFI scores in patients &gt;45 years: Desire 3.05 vs 3.64 (p = 0.002), Arousal 3.45 vs 4.20 (p = 0.001), Lubrication 3.21 vs 3.91 (p &lt; 0.01), Orgasm 3.92 vs 4.38 (p = 0.08), Satisfaction 4.22 vs 4.82 (p = 0.02), Pain 3.41 vs 4.18 (p = 0.02). FSFI scores in patients with VS: Desire 3.35 vs 3.48 (p = 0.75), Arousal 3.55 vs 4.11 (p = 0.06), Lubrication 3.2 vs 3.9 (p &lt; 0.01), Orgasm 3.78 vs 4.46 (p = 0.02), Satisfaction 4.35 vs 4.72 (p = 0.22), Pain 2.94 vs 4.48 (p &lt; 0.01).

Results
The mean age was 42.1 (±13.7) years, 42.4% were &gt; 45 years old, 32.6% (47/144) were menopausal, 41% consulted for VS. FSFI scores in patients &gt;45 years: Desire 3.05 vs 3.64 (p = 0.002), Arousal 3.45 vs 4.20 (p = 0.001), Lubrication 3.21 vs 3.91 (p &lt; 0.01), Orgasm 3.92 vs 4.38 (p = 0.08), Satisfaction 4.22 vs 4.82 (p = 0.02), Pain 3.41 vs 4.18 (p = 0.02). FSFI scores in patients with VS: Desire 3.35 vs 3.48 (p = 0.75), Arousal 3.55 vs 4.11 (p = 0.06), Lubrication 3.2 vs 3.9 (p &lt; 0.01), Orgasm 3.78 vs 4.46 (p = 0.02), Satisfaction 4.35 vs 4.72 (p = 0.22), Pain 2.94 vs 4.48 (p &lt; 0.01).

Conclusions
The domains of desire, arousal, lubrication, satisfaction are decreased in patients &gt;45 years old and those consulting for VS. Pain is the most involved domain. The satisfaction domain would be the least affected among both groups.

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(147) IMPACT OF THE RITE OF TASFIH ON THE SEXUAL HEALTH OF YOUNG ADULT WOMEN
Authors: Kaabia O , Gharbi I , Smaali H , Guefrech O , Maya Bahri Y 
Published: December 2024

Abstract

Introduction
Tasfih is a magical practice exercised by an old woman on girls before puberty, in some North African countries to prevent any pre-marital vaginal penetration. In doing so, it is believed that the hymen becomes unbreachable. It is a taboo practice frequently reported as a cause of unconsummated marriage.

Objective
We aim to study the association between the rite of Tasfih and the domains of sexual function among young adult women.

Methods
This nested case–control study included young adult women aged between 18 and 45. The cases are participants self-reporting a personal history of Tasfih and the controls are self-reported healthy women matching for medical history, age, and relationship status. Data was collected through an online self-administered questionnaire. The sexual function was assessed through validated translations of the Female Sexual Function Index. Female sexual dysfunction is defined by an FSFI score ≤ 26.55.

Results
This study included 104 women with a personal history of Tasfih and 208 controls. Age and other main socio-demographic components were similar between groups. The prevalence of female sexual dysfunction among women with a history of Tasfih was 64.4% compared to 61.2% in the controls. (p = 0.66). There was no statistical difference between both groups in terms of total FSFI score (p = 0.88). There was also no difference between the groups among the six FSFI domains’ scores (Desire, Orgasm, Excitation, Lubrication, Pain, and Satisfaction).

Conclusions
In this study population that has a high prevalence of sexual dysfunction, the magic rite of Tasfih is not associated with worse sexual function scores or more sexual dysfunction.

Disclosure
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(194) QUALITY OF SEXUAL LIFE IN PATIENTS WITH NEURO-UROLOGICAL DISEASES
Authors: Utiyamada N , Konishi Y , Cintra C , Bicudo MC , Glina S 
Published: December 2024

Abstract

Introduction
Neuro-urological symptoms can be caused by a variety of diseases and events affecting the nervous system that are directly related to the location and extent of the injury. The survival rate of patients with these conditions has increased significantly in recent years, but there is not information enought about the quality of life of this population, especially in relation to sexual quality. We know that sexual function has a direct relationship with the level of spinal cord injury and physical, psychological and social factors. This study aims to analyze the demographic profile and evaluate the quality of life and sexual quality of patients, being monitored at our service, with neuro-urological diseases.

Objective
This study aims to analyze the demographic profile and evaluate the quality of life and sexual quality of patients, being monitored at our service, with neuro-urological diseases.

Methods
The WHOQoL-BREF questionnaires associated with IIEF5 were applied for male patients and FSFI for female patients who met the inclusion criteria after reading the informed consent form.

Results
Were collected from 27 patients. Of these, 5 were women and 22 men. 80% of patients had spinal cord trauma, with a median injury time of 10 years (7 months to 36 years). The average age was 41.7 years. We identified 48% are Catholic, 52% consider themselves white, 68% do not have a formal job and 64% of them do not have any children (80% of which are female); 1 patient is bisexual. Forty percent of men show an erectile response to pharmacotherapy (97% oral and 13% intracavernous injection). Sixty percent of patients are satisfied with their level of sexual activity and 40% are dissatisfied; 75% of women are not sexually active – 75% due to lack of a partner and 25% due to marital problems. In relation to quality of life, the domain with the worst evaluation score is related to the environment (58%) and the best evaluated is linked to psychological health (66%). Physical health and social relationships averaged 59% and 60%, respectively.

Conclusions
We can infer that spinal cord injury negatively impacts the quality of life of individuals in the environmental domain, probably due to the mobility limitations imposed by the condition. On the other hand, the domain of psychological health does not seem to be affected in such a significant way. In relation to sexual health, 70% of individuals feel satisfied with their sexual life, despite the usual need for adjuvant pharmacotherapy in males, regardless of the route of administration. However, we observed similarity in the rates of satisfaction and dissatisfaction among men with severe erectile dysfunction and 100% satisfaction of women, even no sexual activity, highlighting the need for further studies in order to evaluate the concreteness of these data and/or the complexities defining interrelations of sexual satisfaction and quality of life, in this particular group of individuals.

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(216) THE RELATIONSHIP BETWEEN SLEEP DISORDERS, QUALITY, AND DURATION AND SEXUAL DYSFUNCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Dilixiati D , Kadier K , Lu J , Laihaiti D , Rezhake R , Azhati B , Rexiati M 
Published: December 2024

Abstract

Introduction
The associations between sexual dysfunction (SD) and sleep disorders, sleep quality, and sleep duration remain unclear.

Objective
To assess the relationship between sleep and SD through a literature review and meta-analysis.

Methods
The PubMed, Scopus, Embase, Ovid MEDLINE, and Cochrane Library databases were systematically searched from inception to November 10, 2022.

Results
Forty-three articles, including 11 longitudinal studies and 32 cross-sectional studies, were included in the quantitative analysis. The pooled relative risk of SD in patients with sleep disorders was 1.97 in longitudinal studies (95% CI, 1.46-2.67, P &lt; .001; heterogeneity: I 2 = 95.0%, P &lt; .001), while the pooled OR of SD in patients with sleep disorders was 2.05 in cross-sectional studies (95% CI, 1.76-2.39, P &lt; .001; heterogeneity: I 2 = 91.4%, P &lt; .001). When compared with controls, subjects with poor sleep quality had a 1.49-fold increased risk of SD (OR, 1.49; 95% CI, 1.31-1.71, P &lt; .001; heterogeneity: I 2 = 73.4%, P &lt; .001). In addition, short sleep duration was associated with the risk of SD (OR, 1.14; 95% CI, 1.06-1.22, P &lt; .001; heterogeneity: I 2 = 0.0%, P = .849).

Conclusions
Our systematic review and meta-analysis results suggest that sleep disorders, especially obstructive sleep apnea, increase the risk of SD in men and women. Poor sleep quality is significantly associated with SD. Short sleep duration is associated with an increased risk of SD.

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(224) ICSI SUCCESS RATES IN PATIENTS WITH AZOOSPERMIA: FRESH OR CRYOPRESERVED SPERM?
Authors: Vinay J , Pieressa N , Saez N , Urrutia C 
Published: December 2024

Abstract

Introduction
Intracytoplasmic sperm injection (ICSI) is a highly complex assisted fertilization technique with several male and female factor indications, including azoospermia. It is not clear whether there is a benefit of using fresh sperm after testicular extraction (TESE) versus frozen–thawed testicular sperm from a previous TESE.

Objective
The objective of the present study is to compare the success rates of ICSI using cryopreserved vs fresh testicular sperm in a single fertility center.

Methods
Analytical study. All patients underwent TESE in a single fertility center between 2017 and 2022. Data was retrospectively studied. The success rate of ICSI, defined as the formation of at least 1 euploid embryo on day 5, was compared between the fresh testicular sperm group vs frozen–thawed testicular sperm and posterior ICSI.

Results
Of the 138 patients who underwent TESE, sperm recovery was achieved in 100 (72.5%). ICSI was performed in 91 cases, 63 (69.2%) with fresh sperm and 28 (30.8%) with frozen–thawed sperm. Of those patients who used fresh sperm, 53 (84.1%) achieved at least 1 euploid embryo in ICSI and of these 30 (56.6%) achieved at least 1 pregnancy. Of those patients who used cryopreserved sperm, 18 (64.3%) achieved at least 1 euploid embryo after ICSI, and of these 11 (61.1%) achieved at least 1 pregnancy. No significant differences were found in the success rate of ICSI with the use of fresh and cryopreserved sperm (p = 0.819).

Conclusions
In the present study, no significant differences were observed in the success rate of ICSI when using fresh or frozen–thawed sperm from TESE. This data could be of great importance when planning assisted reproduction treatments for couples with a severe male factor.

Disclosure
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