bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biocompatible Solutions and Long-Term Changes in Peritoneal Solute Transport
Authors: Elphick Emma H. , Teece Lucy , Chess James A. , Do Jun-Young , Kim Yong-Lim , Lee H. Bahl , Davison Sara N. , Topley Nicholas , Davies Simon J. , Lambie Mark 
Published: August 2018

Background and objectives
The inflammation-driven increase in peritoneal solute transport rate that occurs during long-term peritoneal dialysis is associated with higher mortality, hospitalization, and encapsulating peritoneal sclerosis. Because biocompatible solutions were developed to mitigate these effects, we examined the association with their use and longitudinal peritoneal solute transport rate.

Design, setting, participants, & measurements
We analyzed subjects from the multinational prospective Global Fluid Study with three or more peritoneal solute transport rate measurements >2 months from the start of peritoneal dialysis. Follow-up was for 7.5 years (median, 2.3 years; interquartile range, 1.8–3.6) in biocompatible solutions and 12.8 years (median, 3.2 years; interquartile range, 1.9–4.3) for standard solutions. Using a random intercept/slopes multilevel model, we examined the association of patients using biocompatible solutions and peritoneal solute transport rate over time, adjusting for center effects, dialysate dextrose concentration, baseline dialysate IL-6 concentration, icodextrin use, residual kidney function, and peritonitis.

Results
Of 366 patients, the 71 receiving biocompatible solutions throughout their time on peritoneal dialysis had a mean adjusted dialysate-to-plasma creatinine ratio of 0.67 compared with 0.72 for standard solutions (P=0.02). With duration of treatment, there was a continuous increase in peritoneal solute transport rate in patients using standard solutions (range, 2 months to 4 years). In contrast, patients using biocompatible solutions had peritoneal solute transport rates that plateaued after 2 years of therapy. These changes in peritoneal solute transport rate were independent of baseline inflammation and time-varying predictors of faster peritoneal solute transport rate. In patients suffering episodes of peritonitis while using standard solutions, there was an associated increase in peritoneal solute transport rate of 0.020 (95% confidence interval, 0.01 to 0.03) per episode, whereas in patients using biocompatible solutions, there was no change in this parameter (−0.014; 95% confidence interval, −0.03 to <0.01).

Conclusions
These data suggest that a different temporal pattern in changes in peritoneal solute transport rate occurs during the course of peritoneal dialysis according to solution type and that patients using biocompatible solutions may avoid the increase in solute transport associated with peritonitis.
PEMANFAATAN ARANG TEMPURUNG KEMIRI (Aleurites moluccana (L.) Willd.) SEBAGAI ADSORBEN PADA PEMURNIAN MINYAK KELAPA SAWIT MENTAH/CRUDE PALM OIL (CPO)
Authors: Nuryanto Eka , Askasari Dwi Ratih 
Published: August 2018

Minyak kelapa sawit mentah atau Crude Palm Oil (CPO) adalah produk utama hasil pengolahan buah kelapa sawit. Minyak goreng kelapa sawit dapat dibuat dari CPO dengan melalui proses pemurnian dan pemisahan. Telah dilakukan penelitian pemanfaatan arang tempurung kemiri sebagai adsorben untuk pemurnian CPO. Variabel yang digunakan dalam penelitian ini adalah massa adsorben (5,10, 15,20, dan 25 g), variasi suhu (100, 110, 120, 130 dan 1400C) dan variasi waktu pengadukan (0,5, 1, 2, 2,5, dan 3 jam). Parameter yang dianalisis adalah analisis kadar asam lemak bebas, warna dan karoten. Hasil penelitian menunjukkan bahwa kandungan Asam Lemak Bebas (ALB) terendah diperoleh pada perlakuan suhu 120 oC, massa arang tempurung kemiri 25 g (12,5 % terhadap CPO), dan lama pengadukan 1 jam. Sedangkan untuk parameter warna terendah diperoleh pada perlakuan suhu 130 oC, massa arang tempurung kemiri 15 g (7,5 % terhadap CPO), dan lama pengadukan 1 jam. Arang tempurung kemiri dapat digunakan sebagai adsorben pada pemurnian CPO.
KOMPOSISI ASAM LEMAK DAN KAROTEN KELAPA SAWIT ELAEIS OLEIFERA, INTERSPESIFIK HIBRIDA, DAN PSEUDO-BACKCROSS PERTAMA DI SUMATRA UTARA, INDONESIA
Authors: Siregar Heri Adriwan , Rahmadi Hernawan Yuli , Wening Sri , Suprianto Edy 
Published: August 2018

Tiga ratus sembilan puluh limasampel pohon terdiri dari populasi liar Elaeis oleifera origin Brazil dan Suriname, turunan hibridanya dengan Elaeis guineensis, dan silang balik semu pertama berhasil diamati untuk karakter asam lemak dan total karoten menggunakan gaschromatographydan UV spectrophotometry. Pengamatan dilakukan terhadap lebih dari 648 buah tandan dalam selang waktu 17 bulan. Karakter komposisi asam lemak dan total karoten memiliki keragaman yang lebih luas dibanding varietas komersial di Indonesia saat ini. Populasi pseudo-backcrosspertama baik dari E. oleifera originBrazil maupun Suriname lebih berpotensi diintrogresikan ke dalam program pemuliaan saat ini dibanding populasi liar dan hibridanya disebabkan pertumbuhan batang yang sudah mewarisi sifat E. guineensis. Berhasil ditemukan pada populasi pseudo-backcrosspertama beberapa individu dengan kandungan asam lemak tak jenuh oleat dengan nilai >50% dan kandungan karoten ³2000 ppm. Analisis korelasi antar asam lemak juga dipaparkan dalam tulisan ini yang menunjukkan hubungan yang sedikit berbeda antara populasi hibrida dan pseudo-backcrosspertama, dan bila dibandingkan dengan populasi E. guineensis. Diperlukan penelitian lebih lanjut seperti teknik kultur jaringan dan association studies untuk percepatan penggunaan material turunan E. oleifera.
Direct somatic embryogenesis and plant regeneration in tea by temporary liquid immersion Embriogenesis somatik langsung dan regenerasi tanaman teh melalui perendaman sesaat
Authors: TAHARDI J S , RAISAWATI Tatik , RIYADI Imron , DODD W A 
Published: August 2018

Ringkasan Perbanyakan tanaman teh [Camellia sinen­sis (L.) O. Kuntze] melalui stek tunas berdaun tunggal hanya dapat menghasilkan klon unggul dalam jumlah terbatas. Oleh sebab itu diperlukan metode alternatif dengan teknik kultur sel dan jaringan untuk perbanyakan klonal secara cepat. Dalam penelitian ini dikembangkan metode yang lebih efektif untuk regenerasi tanaman teh melalui embriogenesis somatik langsung. Massa pro­embriogenik dari eksplan kotiledon dihasilkan dengan frekuensi 56,7% dalam media MS padat setengah konsentrasi yang mengandung BAP 2 mg1L. Proliferasi, perkembangan, pendewasaan dan perkecambahan embrio somatik diperoleh dengan sistem perendaman sesaat (SPS) yang menggunakan media MS cair setengah konsen­trasi, yang diperkaya dengan zat pengatur tumbuh dengan berbagai konsentrasi. Proliferasi embrio meningkat 4,3 kali dalam media yang diberi BAP 2 mglL; perkembangan dan pendewasaannya meningkat dengan penambahan kinetin dan ABA masing-masing pada konsentrasi 0,1 mg1L yang 30% diantaranya berkecambah dan membentuk planlet tanpa penambahan zat pengatur tumbuh. Protokol SPS tersebut merupakan sistem in vitro yang berpotensi bagi proliferasi dan perkembang­an embrio somatik tanaman teh yang cepat dan sinkron dari kultur kotiledon, serta regenerasinya menjadi planlet tanpa melalui fase kalus.Summary Tea propagation by single-leaf bud cuttings has limited applications for rapid dissemination of planting materials from new elite clones. An alternative method for rapid cloning by cell and tissue culture technique is necessary. In this study we have established an improved method for tea [Camellia sinensis (L.) O. Kuntze] plant regenera­tion via direct somatic embryogenesis. Clumps of proembryogenic masses were initiated at a fre­quency of 56.7% from cotyledonary slices cul­tured on a half-strength MS agar-gelled medium supplemented with 2 mg/L BAP. Proliferation, development, maturation and germination of so­matic embryos were achieved using the temporary immersion system (TIS) provided with half­strength MS liquid media supplemented with varying concentrations of growth regulators. Em­bryo proliferation increased by 4.3-fold in me­dium provided with 2 mg/L BAP; their develop­ment and maturation were enhanced by the presence of both kinetin and ABA at 0.1 mg/L each. Germination and plant recovery were achieved at a frequency of about 30% without the use of growth regulators. The TIS protocol des­cribed above represents an in vitro system poten­tial for rapid proliferation and synchronized development of tea somatic embryos from cotyledon cultures, and their regeneration into plantlets without an intervening callus phase.
Usando Personas para Mejorar la Experiencia de Usuario de una Aplicación Móvil de Carpooling
Authors: Vargas Fernando , Gaetan Gabriela , Saldaño Viviana 
Published: August 2018

Para evaluar la Experiencia de Usuario, las revisiones de diseño y los recorridos cognitivos generalmente se realizan a través de los ojos del usuario, aunque muchas veces el usuario no está presente. La técnica Personas permite crear usuarios específicos para hacer una revisión experta o un recorrido cognitivo.
El objetivo principal de nuestro trabajo fue identificar aspectos que permitieran mejorar la Experiencia de Usuario de una aplicación móvil. Con el propósito de investigar y evaluar la contribución de la técnica Personas, planteamos: 1) desarrollar una aplicación móvil en base a un proceso iterativo de Diseño Centrado en el Usuario, 2) crear un conjunto de Personas que caracterice a los usuarios de la aplicación móvil, 3) evaluar la aplicación desarrollada realizando una evaluación heurística basada en Personas.
Los resultados de esta evaluación nos permitieron identificar once problemas que afectan negativamente a la Experiencia de usuario con la aplicación UNPAMóvil. Se espera que estos resultados sean insumo para una nueva versión de esta aplicación como también para otras aplicaciones similares.
Fractions of Adenopus breviflorus Extract Modulate Calcium-induced Mitochondrial Permeability Transition Pore Opening in Rat Liver
Authors: Oyedeji Tolulope A. , Akobi Chibuzor I. , Onireti Daniel O. , Olorunsogo Olufunso O. 
Published: August 2018

Abstract
Mitochondrial dysfunction (MD) and impaired apoptotic pathways cause irreversible opening of the Mitochondrial Permeability Transition (MPT) pore, resulting in several pathological conditions e.g. cancer, ageing and neurodegenerative diseases. Many bioactive compounds from plants have been identified as modulators of the MPT pore which makes them possible drugs for the management of MD associated diseases. Adenopus breviflorus (A.breviflorus) is a tropical medicinal plant used in folkore medicine as an abortifacient and in treating gonorrhoea. In this study, the effects of ethylacetate and methanol fractions of A.breviflorus were assessed on rat liver MPT pore and Mitochondrial ATPase (mATPase). The fruit of A.breviflorus was extracted with water to obtain the aqueous Extract (AEAB), which was fractionated using vacuum liquid chromatography (VLC) to obtain ethylacetate and methanol fractions of A.breviflorus (EFAB, and MFAB). The extent of MPT pore opening and mATPase by EFAB and MFAB were assayed spectrophotometrically. The results obtained showed that EFAB and MFAB have no significant inductive effect on the MPT pore in the absence of Ca2+. However, in the presence of Ca2+, EFAB inhibited calcium-induced MPT pore opening in a non-concentration dependent manner. Maximum inhibition of MPT pore opening was 57.1% at 50 μg/ml. Interestingly, MFAB potentiated calcium ion effect by opening the pore further. Specifically, MFAB opened the MPT pore by 11, 10, 17 and 9% at 50, 150, 250 and 350 μg/ml, respectively. Furthermore, EFAB and MFAB inhibited mATPase activity in rat liver mitochondria at 62.5, 187.5, 312.5 and 437.5 μg/ml by 2.6, 18.8, 37.3, 52.6% and 41.8, 6.8, 24.3, 8.4%, respectively. The ethylacetate and methanol fractions of Adenopus breviflorus possess potential phytochemicals that can modulate opening of the mitochondrial permeability transition pore and inhibit mitochondrial ATPase activity in rat liver. These fractions may find use in drug development against diseases where excessive apoptosis takes place.
Haematological and Genotoxicity Evaluations of Phytochemical Compounds from n-Hexane Extract of Uvaria chamae Stem on Selected Organs in Mice
Authors: Akolade Oladipupo R. , Chinwe Alaribe S. , Olalekan Balogun T. , Halima Akere T. , Fatima Ayanda A. , Emuejevoke Toye T. , Herbert Coke A.B. 
Published: August 2018

Abstract
Phytochemical constituents of plants extracts have been well investigated as leads for drug discovery and development. However, aside their immense medicinal properties, their safety is also of paramount importance, therefore evaluating the toxicity of plants extracts and their phytochemicals is an important aspect of quality measures to meet the requirements for consumption.This study was done to identify the volatile phytochemical compounds present in n-hexane extract of Uvaria chamae stems (UCSH) with the aid of gas chromatography-mass spectrometry (GC-MS) and to evaluate the effects of this non-polar extract on DNA using diphenylamine (DPA) and agarose gel electrophoresis assays, also to investigate the haematological parameters using an auto Haematology Analyzer.The GC-MS analysis of UCSH identified some compounds which include; squalene, lupeol, stigmasterol, β-sitosterol, and Benzyl benzoate with excellent medicinal properties. Genotoxicity assays results showed significant reductions in DNA fragmentation in liver and testis cells of mice as against the DNA biomarker and vehicle control group. Haematological results showed significant increase in white blood cells (WBC), red blood cell (RBC), platelets (PLT) and lymphocytes (LYMP) but significant reduction in mean corpuscular - volume (MCV), haemoglobin (MCH), and haemoglobin concentration (MCHC).The present study showed that the phytochemicals present in the n-Hexane extract of Uvaria chamae stems may play protective role in the genomic DNA of liver and testis tissues and also may induce hematological changes which may enhance the immune system.
Evaluation of Some Salicylaldehyde-derived Baylis-Hillman Adducts and Coumarin Derivatives as Potential Antisickling Compounds
Authors: Olomola Temitope O. , Kelani Tawakalit O. , Cyril-Olutayo Mojisola C. , Agbedahunsi Joseph M. 
Published: August 2018

Abstract
Some salicylaldehyde-derived Baylis-Hillman adducts and 3-(chloromethyl)coumarins have been synthesised and evaluated in vitro for their antisickling activities. The compounds were screened for inhibitory and reversal activity against mutated haemoglobin (HbSS) in red blood cells at four different concentrations (4 mg/mL, 2 mg/mL, 1 mg/mL and 0.5 mg/mL) as a measure of their antisickling potentials. Among the synthesized compounds, 6-chloro-3-(chloromethyl)coumarin 4d showed the highest inhibitory activity (83.75±1.90%), followed by 6-chlorocoumarin-3-methylsulfinic acid 5d (80.90 ±0.91%) and the least was tert-butyl-3-hydroxy- 3-(2-hydroxyphenyl)-2-methylenepropanoate 3a (33.33±1.86%). The results obtained from the reversal antisickling experiment showed that the percentage of sickle cells able to revert to the normal biconcave shape was dose dependent. Compound 5d had the highest reversal activity (66.49±1.39%) followed by 6-bromo-3- (chloromethyl)coumarin 4c (59.66±2.95) and 4d (55.50±1.95%) at 4 mg/mL. Compound 4c had higher reversal activity than the standard p-hydroxybenzoic acid at 2 mg/mL, 1 mg/mL and at 0.5 mg/mL. The 3-substituted coumarins 4a-d, and 5d had higher inhibitory antisickling activities than their Baylis-Hillman precursors 3a-d. Effect of 4a-d and 5d on the rate of polymerization of sickle cell heamoglobin was further studied spectrophotomerically using hemolysate of HbSS. The considerable inhibitory and reversal activities of these compounds make them good candidates for further antisickling studies.
Research on Evaluation of Core Competence of Listed Liquor Companies Based on Grey Relational Degree
Authors: Zhang Weimei 
Published: August 2018

Abstract
The Grey Relational Degree method was applied to evaluating the core competence of the ten listed liquor companies. The study found that: the most critical factor affecting the strength of the core competence of listed liquor companies is the technological innovation capability; in general, the core competence of the ten listed liquor companies is weak, with an average Grey Relational Degree of 0.752, indicating more potentials for improvement; in addition, with the exception of Kweichou Moutai, the other nine listed liquor companies are all in an uncoordinated state regarding the development of the six capabilities, and they usually have one or several capabilities lagged behind.
Review of Surface Solar Radiation Projections in Bias-Corrected Euro-Cordex Regional Climate Models
Authors: Bartók Blanka 
Published: August 2018

Abstract
Regional climate models (RCMs) are used in a wide range of climate applications as they can provide high resolution (up to 10 to 20 km or less) and multi-decadal simulations of the climate system describing climate feedback mechanisms acting at the regional scale. However due to different forcing data and physics parametrisations regional climate models might produce different results. This study aims to achieve a state-of-the-art knowledge of bias-corrected surface solar radiation projections coming from 11 EURO-CORDEX regional climate models. First a comparison against 63 GEBA observations is elaborated indicating a general overestimation of surface solar radiation (SSR) in the RCMs by 6.12 W/m2 (4.4%). Next changes in surface radiation between the period of 2031-2060 and 1971-2000 are presented on annual and seasonal time scale. The model projections indicate robust increase in SSR mainly in the western part of the Mediterranean region, while the northern part of the continent is characterised by decreases in SSR till the middle of this century. The study emphasis the need of an overall validation of different climate models before introducing them in impact studies in order to have an overview regarding the uncertainties.
Fluid Flow Control in Domestic Hot Water Systems During Days with Different Radiative Stability Levels
Authors: Budea Sanda , Badescu Viorel 
Published: August 2018

Abstract
This paper presents models/strategies for optimum performance of solar collector in closed loop systems. These models aim to maximize the obtained energy by thermal conversion of solar energy. The mass flow rate of the fluid from the primary circuit of the system is the control parameter. The semi empirical models and optimal control methods are in brief presented. The volume of the storage tank is important and the ratio Vs/Ac between this volume and area of the collectors is a key factor in appropriate sizing of the DHW system. Therefore, the paper establishes a relationship between this ratio and the mass flow rate of the fluid in the collector This paper also analyses the variation of the energetic performance (useful heat flux transferred to the storage tank, heat flux transferred to the water, water temperature in the storage tank) with the volume of the storage tank. Analysis was performed on an extensive set of meteorological data from Timisoara, Romania, with instantaneous data (measured at 15 seconds) for summer days, from July 2009, with different relative sunshine values, σ. Important differences have been observed between days with different stability levels - days more or less stable.
Online Forecasting of the Solar Energy Production
Authors: Paulescu Marius , Stefu Nicoleta , Dughir Ciprian , Blaga Robert , Sabadus Andreea , Paulescu Eugenia , Bojin Sorin 
Published: August 2018

Abstract
Forecasting the solar energy production is a key issue in the large-scale integration of the photovoltaic plants into the existing electricity grid. This paper reports on the research progress in forecasting the solar energy production at the West University of Timisoara, Romania. Firstly, the experimental facilities commissioned on the Solar Platform for testing the forecasting models are briefly described. Secondly, a new tool for the online forecasting of the solar energy production is introduced. Preliminary tests show that the implemented procedure is a successful trade-off between simplicity and accuracy.
Method of Utilization of the Spent Vanadium Catalyst
Authors: Mazurek Krzysztof , Grzesiak Piotr , Drużyński Sebastian , Kiełkowska Urszula , Wróbel Adriana , Szalla Aleksandra 
Published: August 2018

Abstract
A spent vanadium catalyst, from the plant of metallurgical type, was leached in a potassium hydroxide solution to recover vanadium. The effect of time, temperature, concentration of basic, catalyst particle size and phase ratio was studied. The results showed that for a 160-750 μm catalyst leached for 4 h at 313.15 K in the presence of 10% potassium hydroxide solution at a liquid: solid ratio of 20:1, the extent of leaching of V was about 87%. Additionally, separation of vanadium from such a solution was investigated by the ion exchange method. Two types of polymer strongly basic ion exchangers were used. The ion exchange tests indicate that vanadium were loaded from the post-leaching solution with high effi ciency. On this basis a fl owsheet for the proposed process of a complex utilization of the spent vanadium catalyst is presented.
Evaluation on Curing Properties and Kinetics of Isophthalonitrile Oxide
Authors: Fan Yaqin , Tang Chunlan , Hu Qing , Lei Yonglin , Huo Jichuan 
Published: August 2018

Abstract
N,N-dihydroxybenzene-1,3-dicarboximidoyl dichloride was synthesized from benzene-1,3-dicarboxaldehyde and characterized by fourier transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance (1H and 13C NMR). The elastomer was prepared through the 1,3-dipolar cycloaddition of reaction between liquid polybutadiene (LPB) and isophthalonitrile oxide in this work. The tensile strength of different elastomer was enhanced from 0.14 MPa to 0.33 MPa as the elongation at break decreased from 145% to 73%, and the modulus increased from 0.09 kPa to 0.47 kPa. The parameters of kinetic indicated that the curing reaction was fi rst order reaction and the apparent activation energy of each curing system was less than 10.10 kJ/mol when the content of N,N-dihydroxybenzene-1,3- dicarboximidoyl dichloride was increased from 7% to 12%. These results suggested that nitrile oxides achieved curing of polymer binders at room temperature and this work had defi nite guiding signifi cance for the application of nitrile oxides in polymer binders.
Steel and Concrete Elasto-Plastic Models at Bridges with Steel Beams Embedded in Concrete
Authors: Marian Stănescu Răzvan 
Published: August 2018

Abstract
For new railway bridges with short spans (L ≤ 35.00 m) superstructures with steel beams embedded in concrete are recommended or used, which can ensure the requirements of strength and stiffness in particular, regardless of velocity. They are built relatively easily compared to reinforced concrete structures or steel structures, they have high durability if designed, built and maintained correctly and don’t have high sensitivity to fatigue degradation in service. They are also used for road bridges when it is desired to achieve a reduced construction height.
In all the design prescriptions used so far for structures with steel beams embedded in concrete, the calculation is a simplified one, made on a single insulated longitudinal beam of the deck, if certain conditions related to the geometry of the structure are met (obliquity, curvature). Simplifications are also made regarding the state of deformation of the decks made in this constructive solution by introducing an effective moment of inertia in the displacement calculation, as an average of the inertia moments of the cross section considered to be cracked and respectively un-cracked.
The article aims to validate steel and concrete elasto-plastic models, based on an experiment from the technical literature, necessary for complex analyses of the percentage of concrete involved in the stiffness of the cross-sections, in case of bridges with steel beams embedded in concrete.