bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing mechanical ventilator reliability through machine learning based predictive maintenance
Authors: Peruničić Žarko , Lalatović Ivana , Spahić Lemana , Ašić Adna , Pokvić Lejla Gurbeta , Badnjević Almir 
Published: December 2024

Background With the advancement of Artificial Intelligence (AI), clinical engineering has witnessed transformative opportunities, enabling predictive maintenance of medical devices, optimization of healthcare workflows, and personalized patient care. Respiratory equipment plays a vital role in modern healthcare, supporting patients with compromised or impaired respiratory capacities. However, ensuring the reliability and safety of these devices is crucial to prevent adverse events and ensure patient well-being. Objective This study aims to explore machine learning techniques to enhance predictive maintenance for mechanical ventilators. Method The dataset used for this study contains information about 1350 entries of mechanical ventilators, made by 15 different manufacturers and available in 30 distinct models. Different machine learning algorithms, including Logistic Regression, Decision Trees, Random Forest, K-nearest Neighbors, Support Vector Machines, Naive Bayes, and XG Boost are developed and tested in terms of their performance in predicting mechanical ventilator failures. Results The ensemble methods, particularly Random Forest and XGBoost, have proven to be more adept at handling the complexities of the dataset. The Decision Tree and Random Forest models both showed remarkable accuracies of approximately 0.993, while K-Nearest Neighbors (KNN) performed exceptionally with near perfect accuracy. Conclusion Adoption of automated systems based on artificial intelligence will help in overcoming challenges of ensuring quality of MDs that are already being used in healthcare institutions. Implementing machine learning-based predictive maintenance can significantly enhance the reliability of mechanical ventilators in healthcare settings.
Analysis of research trends and hotspots in emergency department overcrowding: A bibliometric study based on VOSview and Scimago Graphica
Authors: Chen Hong , Chen Feng , Luo Jie , Chen Sheng 
Published: December 2024

Objective Analyze the research trends and hotspots in emergency department overcrowding derived from the Web of Science Core Collection database. Methods The Web of Science Core Collection database was utilized as the search data source for the bibliometric analysis, and the associated articles published from January 1, 1990, to October 1, 2023.The search was executed using the following formula: TS = (crowded OR overcrowd OR crowding OR overcrowding) AND TS = (Emergency department). VOSviewer, Scimago Graphicaand and additional tools were utilized for bibliometric analysis, and visual knowledge graphs were created. Results A total of 1869 articles were included in this study. The country with the largest number of publications is the United States. The primary research institution is the University of Toronto. Jesse M. Pines and his group at George Washington University have the greatest influence in the field of emergency department overcrowding research. Carlos A. Camargo is the author with the highest h-index in this field. High-frequency keywords include “length-of-stay”, “impact”, “mortality”, “triage”, “association”, “outcomes”, “time”, “management”, “access block”, and “quality”. The clustering graph reveals that all keywords fall into seven categories. Conclusion We recommend intensifying research on emergency department overcrowding in more developing countries. In the future, the application of emerging technologies in emergency medicine as well as the mental health of emergency patients and medical staff may become research hotspots in this field.
Unveiling Adolescent Struggles: Exploring the Interplay of Childhood Trauma, Emotional Regulation, and Externalizing Symptoms
Authors: Sharma Prerna , Sen Mahadev Singh , Sinha Uday , Kumar Deepak 
Published: December 2024

Aim: This study examines the interaction between childhood trauma, emotional regulation, and externalizing symptoms among adolescents aged 13 to 19 years, elucidating the role of emotional regulation as a mediator in the relationship between childhood trauma and externalizing behaviors. Design: This study utilizes a cross-sectional observational study design. Method: A sample of 182 adolescents attending child and adolescent services was assessed. Demographic characteristics were analyzed using descriptive statistics. Childhood trauma was measured using the Childhood Trauma Questionnaire—Short Form (CTQ), emotional regulation through the Difficulties in Emotion Regulation Scale (DERS), and externalizing symptoms using the Child Behavior Checklist (CBCL). Analysis: Hierarchical multiple regression and mediation analyses were conducted to explore the relationships. Results: Most participants were 16–19 years old (66.5%), and 54.9% were female. Notably, childhood trauma positively correlated with externalizing symptoms ( r = 0.39, P < .001) and difficulties in emotion regulation ( r = 0.25, P < .01). Emotional regulation, as measured by DERS, exhibited a significant positive correlation with externalizing symptoms ( r = 0.23, P < .01). Hierarchical regression analysis revealed that emotional regulation played a significant role in predicting externalizing scores ( β = 0.358, P < .001). Mediation analysis demonstrated both direct (B = 0.16, P < .001) and indirect effects (B = 0.036, P = .0273) of childhood trauma on externalizing behaviors through emotional regulation. Conclusions: This study underscores the multifaceted nature of externalizing behaviors and highlights the interconnectedness of childhood trauma and emotional regulation in their manifestation. Findings suggest that utilizing emotion regulation strategies is pivotal in treatment of externalizing symptoms among adolescents presenting with traumatic history. The proposed mediation model provides valuable insights for developing targeted interventions and preventive strategies in clinical settings.
Reducing the Waiting Time for Retinopathy of Prematurity Evaluation—A Quality Improvement Interventional Study
Authors: Dangayach Naveen , Gupta Shalini , Jain Rohit , Goyal Abhishek , Mittal Jaikrishan 
Published: December 2024

Aim To reduce the waiting time of babies for retinopathy of prematurity (ROP) evaluation at a tertiary care paediatric centre in Rajasthan and check its impact on follow-up. Methods It was a Quality improvement (QI) interventional study in which a QI team was made. A Fishbone root cause analysis after 1 month of observation was done to understand the reasons for the high waiting time for ROP screening in both IPD and OPD. This was followed by three plan-do-study-act (PDSA) cycles: segregation of the IPD & OPD patients by fixing two separate days and hiring a full-time paediatric ophthalmologist; distribution of informative digital/printed leaflets; timely reporting of staff, dilation of pupils, equipment availability and proper examination order. Average waiting time and maximum waiting time were measured before and after the PDSA cycles. Results After the completion of all PDSA cycles: Overall maximum waiting time for OPD and IPD patients was reduced from 130 and 138 minutes to 96 (26.2%) and 97 minutes (29.7%), respectively. The average waiting time for OPD and IPD patients was reduced from 96.2 and 92.4 minutes to 76.5 (20.5%) and 73.4 minutes (20.6%), respectively. The number of patients coming for ROP follow-up also increased. Conclusion The QI initiative using the point of care QI model (POCQI) was quite effective in reducing the maximum and average waiting time of babies undergoing ROP screening. It also increased their follow-up at our centre.
Challenges and Related Interventions Being Practiced by the Employees of a Tertiary Care Centre Amidst the Lockdown Due to the COVID-19 Pandemic
Authors: Saini Ruchi , Saini Sushma Kumari , Kaur Sukhpal , Sharma Nitasha , Pebma Monika , Kalyan Geetanjli , Das Karobi 
Published: December 2024

Introduction The lockdown to curb COVID-19 pandemic has affected day-to-day life of the public. The people faced many challenges in their daily life and took various measures to overcome them. Objective To explore challenges being faced by the employees of tertiary care centre during the lockdown period due to COVID-19 pandemic and various interventions undertaken by them to overcome those issues. Methods A descriptive cross-sectional study design was adopted in the study. Purposive sampling technique was used to enrol 151 class III and IV employees of a tertiary care hospital. The data was collected using a questionnaire comprising of socio-demographic profile sheet and questions regarding health-related challenges, preventive practices and the effect of lockdown on basic life activities of the employees of tertiary care Institute during COVID-19 pandemic. Ethical clearance was obtained from the Institutional Ethics Committee and written informed consent was taken from each participant. Results During lockdown, there was an increase in food intake, weight, duration of physical activity, frequency of bathing and changing clothes, involvement in household chores and time spent with children. However, there was no significant change in the sleeping patterns and sexual activity of the participants. They faced various difficulties in medical consultation of non-covid issues, could not procure medicines and skipped vaccinations of their children. The findings also show that people practiced various measures such as herbal and home remedies increased their frequency and duration of hand-washing and sanitisation and started wearing personal protective equipment to some extent to prevent transmission of COVID-19 infection. Conclusion and Recommendations The imposition of lockdown to prevent the spread of COVID-19 infection affected the basic lifestyle of people and changed their behaviours. The people faced many difficulties in accessing healthcare services.
Transforming Practical Evaluations: A Comparative Approach to Students’ Satisfaction with OSCE Versus Traditional Methods
Authors: K Vijayalakshmi , S Revathi 
Published: December 2024

Background Objective Structured Clinical Examination (OSCE) is a method of clinical evaluation which is a competency-based, systematic and objective method for the evaluation of students. The present study was carried out to compare the nursing students’ satisfaction between OSCE and Traditional Practical Examination (TPE) in psychiatric nursing at, Chennai, South India. Methods The study was conducted using the randomized cross-over research design with two groups in a selected Nursing College, Chennai among 84 III-year B.Sc. Nursing students (42 students in each group), were selected using the consecutive sampling technique. The participants were randomly assigned to Group I and Group II based on their second-year university examination scores, using the odd-even method. Data was collected using the baseline characteristics of the students and rating scale on satisfaction of evaluation methods (OSCE and TPE). The data were entered into Excel and analyzed using SPSS for Windows (20.0, IBM Corp) with appropriate statistical tests. Results Overall students’ satisfaction scores were higher in OSCE (98.26 ± 6.44) while comparing to TPE (89.82 ± 7.27, p < .001). Students overwhelmingly perceived positively (strongly agreed) toward OSCE on most of the items on quality of assessment, reliability and validity. Conclusion The study found that students reported high levels of satisfaction with the OSCE, indicating its effectiveness as an evaluation tool. This suggests that the OSCE contributes positively to students’ learning experience and engagement in psychiatric nursing education.
Immunomodulatory Effects of Andrographis paniculata Leaf Extract in Cyclophosphamide-induced Immunosuppressed Mice
Authors: Kalona Patrick A. , Sundaresan Uma , Muthiah Chellappandian , Ganesan Ariharasivakumar 
Published: December 2024

Background Cyclophosphamide is one of the most extensively used chemotherapeutic drugs and is employed to treat several malignancies. Cyclophosphamide often comes with several unpleasant side effects. The primary negative consequence of cyclophosphamide in clinical chemotherapy is immunosuppression, which can lead to life-threatening complications. Objectives: The present work was dedicated to exploring the therapeutic effects of Andrographis paniculata against cyclophosphamide-induced immunosuppression in mice. Materials and Methods The BALB/c mice were treated with 80 mg/kg of cyclophosphamide to achieve immunosuppression and treated with 250 and 500 mg/kg of A. paniculata extract. 10 mg/kg of levamisole was used as a standard drug. After the completion of the treatments, the body weights of the experimental animals were measured. The immune organs (spleen and thymus) were determined by standard methods. The levels of blood components were studied using an automated hematological analyzer. The macrophage phagocytic index, humoral response, and delayed immune response were studied by standard methods. The histopathological analysis was done on the heart, spleen, and thymus. Results The treatment with 250 and 500 mg/kg of A. paniculata extract substantially increased the body weight and elevated the immune organ index in the immunosuppressed mice. The changes in the levels of hematological parameters were successfully modulated by A. paniculata. The levels of macrophage phagocytic index and delayed and humoral immune responses were boosted by the A. paniculata extract treatment in the immunosuppressed mice. The outcomes of histopathological analysis exhibited that the A. paniculata extract attenuated the cyclophosphamide-induced damage to the heart, thymus, and spleen tissues. Conclusion The findings of the current work validate the immunomodulatory properties of A. paniculata extract in cyclophosphamide-induced immunosuppressed mice. Hence, it was clear that A. paniculata can be a talented immunomodulatory agent to treat immunological complications.
Research on broadband vibration reduction performance of high-damping stainless steel fiberboard
Authors: Zhang Jiyang , Chen Kean , Xu Ying , Li Hao , Luo Jianfeng , Zhang Tingying , Ren Shuwei , Tian Fenghua , Wang Lei 
Published: December 2024

This study investigates the application of stainless steel fiberboards (SFBs) for effective vibration reduction in the head section of autonomous underwater vehicles (AUVs). SFBs offer a compelling combination of lightweight design, high static load capacity, and broad-band vibration reduction. To understand their effectiveness, we analyzed the mechanisms behind SFBs’ superior compressive strength and high-damping properties. Furthermore, a finite element model (FEM) of the AUV head section was created using COMSOL software. The model’s accuracy was validated by comparing simulation results with experimental data. This validated model was then employed to calculate the energy consumption of the bearing plate within the AUV’s head section, providing valuable insights for optimizing SFB design for specific vibration reduction applications. The results demonstrate that SFBs of various thicknesses exhibited higher energy consumption ratios compared to the aluminum plates. This finding reinforces the effectiveness of the SFB’s damping mechanism. Additionally, across the 0–6 kHz frequency range, SFBs significantly outperform the aluminum plates, achieving an average improvement of approximately 18 dB in vibration level difference (VLD). These results highlight the excellent vibration reduction performance of SFBs.
Acute renal failure during treatment with Zoledronate in cancer patients
Authors: Ben Kridis Wala , Amor Mariem Ben , Khanfir Afef 
Published: December 2024

Background Standard treatment for bone metastases is based on bisphosphonates such as zoledronic acid. The objective of this study was to evaluate the incidence of acute renal failure during treatment with Zoledronate and to analyze its correlated factors. Materials and methods This is a retrospective study carried out at the medical oncology department of Habib Bourguiba University Hospital in Sfax, between January 2022 and March 2022. The creatinine dosage was carried out using the Jaffe-type colorimetric method. Acute renal failure was defined by the Kidney disease Improving Global Outcomes criteria. Results 48 patients were included. The average age was 56.9 ± 10.7 years with a sex ratio (M/F) equal to 0.5. The average weight of the patients was equal to 68.5 ± 16.4 kg. 62.5% of patients were followed for breast cancer, 12.5% had lung cancer and 12.5% had prostate adenocarcinoma. The mean serum creatinine before the start of treatment was equal to 74.3 ± 34.3 µmol/l 50.84 ± 0.11 mg/dl). The mean pre-therapeutic clearance was 94.1 ± 40.2 ml/min with 4 cases of moderate renal impairment (8.3%). Acute renal failure according to KDIGO during treatment with Zoledronic acid was observed in 9 cases (18.8%), thus requiring a dose reduction. Acute renal failure was significantly associated initial clearance <60 ml/min and low weight of 53.44 kg (p = 0.003 and p = 0.01 respectively), in multivariate analysis. Conclusion Our study concluded that factors associated with acute renal failure were low weight and clearance less than 60 ml/min.
Oculofacial plastic surgery in the cancer patient: A narrative review
Authors: Clabeaux Carson E. , Rana Harkaran S. , Patadia Amol H. , Dertinger Jake E. , Germann Colby , Allen Richard C. 
Published: December 2024

With the advances in systemic therapy and radiotherapy, the life expectancy of patients battling cancer has increased. The oculofacial plastic surgeon should be aware of the potential impacts a patient in remission or one being actively treated may pose. The goal of this review is to discuss the considerations a surgeon should have in this patient population. Methods The authors performed a computerized search using PubMed, Embase, and Google Scholar. The search terms used were “chemotherapy AND surgery”, “immunotherapy AND surgery”, “radiotherapy AND surgery”, “nutrition AND surgery”, “(oculoplastic OR orbit OR eyelid OR lacrimal OR puncta) AND (chemotherapy OR immunotherapy OR radiotherapy)”, “(facial OR facial plastic OR oculoplastic) AND (chemotherapy OR immunotherapy OR radiotherapy)”, “(cancer OR malignancy) AND surgery”, “(cancer OR malignancy) AND (surgery OR surgical) complications”, “wound healing AND (cancer OR malignancy)”, “infection AND (cancer OR malignancy)”, “(bleeding OR blood loss) AND (cancer OR malignancy) AND surgery”, “(chemotherapy OR immunotherapy OR radiotherapy) AND wound healing”, “(chemotherapy OR immunotherapy OR radiotherapy) AND (bleeding OR blood loss)”, “(chemotherapy OR immunotherapy OR radiotherapy) AND infection”. Results A total of 89 articles, published from 1993 to 2023 in the English language or with English translations were included. Articles published earlier than 2000 were cited for foundational knowledge. References cited in the identified articles were also used to gather further data for the review. Conclusions and Relevance Patients who are being treated for cancer or are undergoing current treatment for cancer require special considerations. Systemic therapies and radiotherapy impact the physiology of patients and the integrity of tissue in ways that significantly impact surgical interventions. It is imperative for the oculofacial plastic surgeon to have a complete understanding on how a previous or current diagnosis of cancer can influence surgical outcomes.
Short-term outcomes of AVN CAGE implantation for early-stage osteonecrosis of the femoral head
Authors: Guo Shaoyi , Deng Wang , Xiao Wenzhou , Zhang Yunfeng , Yang Dejin , Zhou Yixin 
Published: December 2024

Purpose: Considering the low survival rate for the numerous hip-preserving procedures developed for treating early-stage osteonecrosis of the femoral head (ONFH), this study aimed to evaluate short-term clinical outcomes following avascular necrosis (AVN) CAGE implantation. Methods: 58 hips with early-stage ONFH (44 with Association Research Circulation Osseous [ARCO] stage 2 and 14 with stage 3A) treated with the AVN CAGE between August 2018 and December 2021 were included. The survival rates were analysed using radiographic progression and conversion to subsequent total hip arthroplasty (THA) as endpoints. Results: The mean follow-up period was 22.2 ± 8.2 months. 11 hips progressed to ARCO stage 3B/4, and 6 underwent THA. The estimated 2-year radiographic survival rates were 89.1% and 59.0% for patients with ARCO stages 2 and 3A, respectively. The estimated 2-year radiographic survival rates were 92.9% and 76.3% for Japanese Investigation Committee type B/C1 and C2, respectively. The overall estimated 2-year THA-free survival rate was 88.9%. Advanced disease stage and a large necrotic area were independent risk factors for radiographic progression. Conclusions: AVN CAGE combined with standard core decompression was a promising hip-preserving option for patients with no signs of collapse, small necrotic areas, or medially located necrotic locations.
Patterns and Correlates of Multiple tobacco Product use Among people With HIV in India
Authors: Nagawa Catherine S. , Selvamuthu Poongulali , Kumarasamy Nagalingeswaran , Balakrishnan Faith Beulah , Rigotti Nancy A. , Kruse Gina R. 
Published: December 2024

Introduction: Multiple tobacco product (MTP) use may intensify nicotine dependence and reduce the chances of quitting success. Characterizing MTP use in people with HIV (PWH) in low- and middle-income countries (LMICs) is needed to guide cessation approaches in this group. This study aimed to identify patterns and correlates of MTP use among PWH in a single clinic. Methods: This study was conducted among PWH at a clinic in Chennai, India. Participants completed an in-person survey providing information on tobacco use, demographics, and cessation-related factors. This analysis focused on PWH who reported current tobacco use. We used Fisher’s exact test (categorical variables) and the Wilcoxon rank-sum test (continuous variables) to assess statistical differences in demographics and cessation-related factors between PWH who used single vs multiple tobacco products. Results: Of 154 PWH adults surveyed, 58 (37.7%) reported current tobacco use. Most PWH currently using tobacco were male (n = 49/58, 84%), with a median age of 21 years (IQR: 10). Forty-six percent (n = 27/58; 95% CI: 33% - 60%) reported MTP use, combining three products (IQR: 3) on average. Those who used multiple products were more likely to have a higher education level (n = 12/27, 44%; 95% CI: 25% - 65%) compared to those who used a single product (n = 2/16, 12%; 95% CI: 1% - 38%) ( P-value = 0.03). A lower proportion of participants who reported MTP use were unemployed (n = 1/27, 97%; 95% CI: 0% - 19%) compared to those who used a single product (n = 5/16, 31%; 95% CI: 11% - 59%) ( P-value = 0.04). All other factors, including gender, primary language, marital status, and cessation-related factors, were comparable between PWH who used a single tobacco product and those who used multiple products. Conclusion: Among PWH who currently smoke, almost half use tobacco combined multiple products. MTP use in PWH was linked to higher education levels and employment in this single clinical setting.