bluuebunny/crossref_metadata_2025_split huggingface dataset:
Propofol-induced transient arginine vasopressin deficiency
Authors: Luppino Michael D , Nguyen Huyen , Smale Matilda , Madigan Rebecca , Burt Morton G , Umapathysivam Mahesh M 
Published: October 2024

Summary
We describe and characterise the case of a 26-year-old female undergoing surgery for a right-sided sinonasal alveolar rhabdomyosarcoma who developed profound, transient arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus (DI)) associated with anaesthesia. In this case report, we characterise the development of AVP-D with serial copeptin and paired urine and serum osmolality measurements. Based on the anaesthetic agent’s profile and the literature, we attribute this presentation to propofol exposure. We present a description of the literature on anaesthesia-associated DI as well as poignant learning points.

Learning points

Exposure to anaesthetic agents is a rare cause of self-limited but sudden and profound arginine vasopressin deficiency (AVP-D) or arginine vasopressin resistance (AVP-R).

Sevoflurane has been associated with AVP-R and propofol with AVP-D, although the responsible agent may be difficult to identify.

Differentiation of AVP-R and AVP-D can be made based on copeptin concentration, where available, or clinical response to desmopressin.

Whilst the patient is anaesthetised, intravenous fluid replacement should be targeted to match urine output until the patient is able to drink to thirst. This should be clearly communicated to staff and the patient.

Rapid resolution of AVP-R/AVP-D when the causative agent is discontinued has been reported with both propofol and sevoflurane. As such, switching the agent used to maintain anaesthesia may terminate increased urine output in a clinically meaningful timeframe.
The crystal structure of R3Fe0.1Ga1.6S7 chalcogenides (R – La, Ce, Pr and Tb)
Authors: Blashko N.M. , Marchuk O.V. , Fedorchuk A.O. 
Published: October 2024

The paper reports the study of the crystal structure of chalcogenides of the composition R3Fe0.1Ga1.6S7 (R = La, Ce, Pr and Tb) as promising materials predicted to possess interesting nonlinear optical and electrical properties. Samples of stoichiometric composition were synthesized by co-melting the elements in quartz containers evacuated to a residual pressure of 10–2 Pa at the maximum synthesis temperature of 1100 °C. The crystal structure of the chalcogenides La3Fe0.1Ga1.6S7 {a = 10.1884(6) Å, c = 6.0515(4) Å}, Ce3Fe0.1Ga1.6S7 {a = 10.0864(4) Å, c = 6.0440(3) Å}, Pr3Fe0.1Ga1.6S7 {a = 9.9853(3) Å, c = 6.0648(2) Å} and Tb3Fe0.1Ga1.6S7 {a = 9.6692(7) Å, c = 6.0799(5) Å} was studied by X-ray powder method. It was determined that the structure of the synthesized phases belongs to the hexagonal symmetry (La3CuSiS7 structure type; space group P63). The structure of the complex chalcogenides (A), (B), (C) and (D) is based on the R3Ga1.67S7 sulfides (R = La, Ce, Pr, and Tb) by substituting gallium atoms in the 2a sites with atoms of statistical mixture M1{0.57(2) Ga + 0.10(2) Fe}, M2{0.56(1) Ga + 0.10(2) Fe}, M3 {0.61(8) Ga + 0.09(1) Fe} and M4 {0.57(2) Ga + 0.10(2) Fe}, respectively. Rare earth atoms are localized in the 6c sites and center sulfur atoms to form trigonal prisms with an additional atom [R 3S13S21S3]. Atoms of statistical mixtures M1, M2, M3, M4 are localized in the 2a sites forming [M 6S2] octahedra. Ga atoms in the 2b sites are surrounded by four sulfur atoms [Ga 3S11S3].
Free Vibration Analysis for Polyester/Graphene Nanocomposites Multilayer Functionally Graded Plates
Authors: Abd Alqader Shahad Qusi , Bedaiwi Bashar Owaid , Njim Emad Kadum , Takhakh Ayad M. , Hadji Lazreg 
Published: October 2024

In the current work, an FGM nanocomposite made of multi-layers of graphene nanoparticles and a polyester-based matrix was constructed using the molds with a hand lay-up technique to attain an accurate shape and reduce defects in the final product. The desired models have four, six, and 11 layers and different volume fractions of nanoparticles (0.5, 1, 2, 3, 4, and 5%). This study conducted various experimental tests to analyze the free vibration characteristics of functionally graded composite sandwich rectangular structures with simply supported boundary conditions to evaluate the significance of hole number and cutout location in fundamental frequencies. For holes, three types are used (2, 4, and 6) holes with a 10 mm diameter, while for cutouts, three geometrical designs are used (circular, rectangular, and triangular) with various aspect ratios (r = 1, 1.5, 2, and 2.5).
A numerical study was carried out to validate the experimental solution, employing modal analysis and finite element analysis (FEA) using ABAQUS software tools. From the findings, the experimental findings and numerical calculations exhibit a satisfactory level of concurrence, displaying a maximum discrepancy of 9.5%. The results show that the fundamental frequency decreases by increasing the cutouts' aspect ratio (r=a/b). There is minimal variation between r =1 and r= 1.5, but a noticeable decrease is observed at an aspect ratio of r= 2.5. This difference is primarily influenced by the type of material gradient and the number of holes, specifically for a given thickness of the functionally graded (FG) plates.
The Effect of Lactic Acidosis on Neonatal Outcomes in Premature Infants
Authors: Perepelitsa Svetlana A. , Molchanov Igor V. 
Published: October 2024

The aim of the study was to evaluate neonatal outcomes in preterm infants.Materials and methods. The study included 58 premature neonates divided into 2 groups: «A» (N=34) with an adverse neonatal period ending in death and «B» (N=24) who survived. Clinical assessment of the infant, measurement of blood gases, acid-base balance (ABB) and lactate, recording of lung ventilation parameters, calculation of mean airway pressure, oxygenation index (OI) and ventilation efficiency index (VEI), neurosonography and, in case of death, pathological and histological examination of the brain were performed.Results. Elevated lactate was found in 24 patients (70.5%) in group A and in 12 patients (50%) in group B. The mean lactate levels in groups A and B were 8.1±3.3 and 6.3±2.8 mmol/L, respectively. In group A, 19 (55.9%) infants had severe acidosis, corresponding to a pH of 7.19 to 6.80. In group B, only 8 (33.3%) infants had a pH between 7.0 and 7.19. At birth, neonates in both groups were found to have a base deficit (BD), which was significantly lower in group A than in group B (P=0.004). There were no trends toward reduction of acidosis or normalization of ABB in infants in group A. Plasma BE levels in group B had returned to normal by 96 hours postpartum. The frequency of grade II, III peri/intraventricular hemorrhage (PIVH) and hemorrhage of other localization in group A were 8 (23.5%), 9 (26.5%), and 3 (8.8%), respectively. In group B, grade I PIVH and hemorrhage of other localization occurred in 5 (20.8%) and 1 (4.2%) cases, respectively. In neonates with grade II PIVH, severe lactic acidosis was diagnosed at birth: venous blood pH was 6.97 [6.8; 7.22], BE was (–21.6) [–30; –7.2] mmol/L, lactate level was 8.5 [6.3; 12.9] mmol/L, and pO₂ was 50.5 [20.5; 64] mm Hg. In infants with grade III PIVH, pH was –7.26 [7.12; 7.28], BE was (–8.1) [–8.9; –7] mmol/L, lactate was 7.6 [4.8; 8.9] mmol/L, and pO₂ was 33 [30; 50] mm Hg. Cell damage of varying severity affected all brain structures, as evidenced by absence or deformation of nuclei and nucleoli, and peripheral chromatin condensation. Morphological immaturity of brain structures was another negative factor.Conclusion. Lactic acidosis diagnosed at birth in premature infants is one of the indicators of perinatal hypoxia severity. Critical pH, BE, and lactate levels, as well as lack of response to treatment, contribute to structural brain damage and worsen prognosis. Severe changes in oxygen and lactate levels that persist for two days after birth lead to severe PIVH and irreversible brain changes.
International Trends in Zinc Treatment for Diarrhea
Authors: Karlsson Omar , Kim Rockli , Subramanian S. V. 
Published: October 2024

BACKGROUND
Diarrhea is a leading cause of death among children &lt;5 years of age and can have long-term adverse consequences for human development. The World Health Organization has recommended the therapeutic use of zinc for the treatment of diarrhea, along with oral rehydration solutions, since 2004. We studied recent trends in the use of zinc to treat diarrhea in 23 low- and middle-income countries.

METHODS
A repeated cross-sectional design of 46 Demographic and Health Surveys from 23 countries was used to estimate the average annual change in zinc treatment across recent years. The earlier surveys were conducted in different years from 2009 to 2014, and the latest surveys were conducted in different years from 2015 to 2023, with an average gap of 6 years between surveys. A diarrhea episode during the 2 weeks before the survey and the treatment of diarrhea using zinc and oral rehydration solutions among children &lt;5 years old was identified using an interview with mothers.

RESULTS
In the pooled sample, the treatment of diarrhea in children &lt;5 years of age using zinc increased from 2% in the earlier surveys to 27% in the more recent surveys, or an average annual increase of 4 percentage points (pp). The prevalence of zinc treatment increased in all 23 countries, ranging from 9 pp per year on average in Sierra Leone to 1 pp in Cambodia.

CONCLUSIONS
A large increase in the use of therapeutic zinc to treat diarrhea in children was observed in recent years. However, coverage remains incomplete.
Repository structures: Impact on collaboration and productivity
Authors: Shakikhanli Ulvi , Bilicki Vilmos 
Published: October 2024

AbstractThis study examines the connection between repository structure, productivity, and management practices in software development collaboration. Analyzing open-source projects, it finds higher collaboration in Multi repository teams than in Mono repository teams, implying a nuanced interaction with team size. Effective management and well-structured architectures correlate positively with productivity, emphasizing strategic management's importance for optimizing collaboration and efficiency in software projects.
Una propuesta de enseñanza para comprender cómo nos afecta el cambio climático, cómo se produce y cómo podemos aportar a la mitigación de sus efectos
Authors: Galeano-Marín Juan David 
Published: October 2024

A continuación, se presenta una propuesta de enseñanza fundamentada en algunos principios de la Teoría de Aprendizaje Significativo Crítico (TASC) de Moreira (2010) y secuenciada según las fases del ciclo didáctico de Neus Sanmartí y Jorba (1996) para comprender cómo nos afecta el cambio climático, cómo se produce y cómo podemos aportar a la mitigación de sus efectos. Se retoma la evaluación formativa y una reflexión pedagógica desde la Investigación Acción Educativa de Bausela (2004) y Restrepo (2004) para determinar el impacto de la propuesta y construir unas conclusiones.

Desde lo disciplinar, se propone un referente conceptual del cambio climático, la variabilidad climática, tiempo y clima basado en autores como Naciones Unidas (2022); el Grupo Intergubernamental de Expertos sobre el Cambio Climático IPCC (2013); el Instituto de Hidrología, Meteorología y Estudios Ambientales IDEAM y la Universidad Nacional de Colombia UNAL (2018) y el Programa de Investigación de Cambio Global de Estados Unidos en inglés United States Global Change Research Program USGCRP (2009).

Considerando los resultados más relevantes se pudo concluir que el diseño de este tipo de propuestas es muy importante, porque el Cambio Climático es un problema global que afecta a todos los habitantes y especies del planeta, es fundamental que los estudiantes sepan sobre él para desarrollar una conciencia ambiental, comprender la importancia de la responsabilidad social, prepararse para el futuro y participar como ciudadanos activos e informados.
New Method Determines Optimized Reference SDM for MIMO Testing
Authors: Underwood Marcos A. 
Published: October 2024

Abstract
The paper presents a new method for vibration testing of articles such as satellites, aerospace subsystems, transportation subsystems, civil structures, or articles whose reliability in operation may be evaluated using either mechanical or acoustic vibration testing. The method can be used for direct field or reverberant acoustic test facility testing (acoustic) systems or multiple-exciter (mechanical) testing systems to perform vibration testing. The method improves the ability of Multiple-Input-Multiple-Output (MIMO) acoustic testing systems to create diffuse or other types of acoustic fields and MIMO mechanical testing systems to produce vibration responses conforming to an initial reference Spectral Density Matrix (SDM) specification in the least mean-square error (LMSE) sense. It provides an updated positive definite or semi-definite reference SDM that enables such tests to run with less error, using minimum required drive power, as a function of the initial definition of the reference SDM, by modifying its coherence and phase off-diagonal terms, to approximate initially defined off-diagonal terms in the LMSE sense, but maintaining its initially defined diagonal terms exactly, while accounting for physical limitations existing in the overall MIMO testing system.
A New Method Using Pseudovelocity-Based Fatigue Analysis to Determine the Effectiveness of Acoustic Fields Used for Acoustic Testing
Authors: Underwood Marcos A. , Lamparelli Marc D. 
Published: October 2024

Abstract
This paper summarizes results from the use of advanced adaptive multiple-input, multiple-output (i.e., MIMO) control for direct field acoustic testing to excite an aluminum-honeycombed 1.22 m × 2.44 m (4 ft × 8 ft) test panel with MSI-DFAT's near-diffuse acoustic field and four nondiffuse acoustic fields using three panel orientations, and two speaker configurations. The five fields have the same overall sound pressure level (OASPL) and 1/3-octave sound-pressure-level (SPL) spectrum. Test and analysis results demonstrate a dependence of the test panel's response characteristics to each acoustic-field excitation, showing that the near-diffuse field excites experimental-modal-analysis-identified test panel modes effectively, whereas nondiffuse fields excite these modes ineffectively. Differences are attributed to the relative diffuseness of fields. Partial fatigue damage values from 20 accelerometer locations are determined from pseudovelocity (PV) outputs from single-degree-of-freedom (SDOF) models at each modal frequency excited by their response time histories, for each acoustic field, to quantify the relative ability of acoustic fields to detect workmanship flaws of typical test articles. Fatigue-damage values are obtained from PV response time histories of SDOF models at identified modal frequencies, which are rainflow-cycle counted with the partial-damage coefficients calculated using the Palmgren-Miner rule. A new form of vibro-acoustic gain based on PV power spectral densities (PSDs) is also introduced and correlated with these experimental results, since the PV response PSDs of a test article undergoing random vibration are proportional to modal stress at their frequencies. This paper shows that the modal stress caused by acoustic-field types is an important consideration for acoustic testing of satellites and other spacecraft, since using a nondiffuse field may result in an acoustic test that doesn't detect workmanship flaws in a test article, even though the acoustic environment is achieving the same specified OASPL and average acoustic 1/3-octave SPL spectrum.
Assess the knowledge regarding thyroid disorders among patients attending medical OPD
Authors: Rana Sonali , Sati Rahul , Thapa Tabita , Rana Priyanka , Joshi Manisha , Praveen Shama , Pundir Namrata , Kumar Chandan 
Published: October 2024

Background: The thyroid gland is an endocrine gland consisting of two lobes connected by an isthmus, in the neck. It is found in front of the neck below the Adams apple. Thyroid gland though a small structure on the anterior aspect of neck has many important functions to perform, failing in its duty might lead to serious consequences.
Methods: A non-experimental descriptive research design was conducted to assess knowledge regarding thyroid disorders among patients attending medical OPD in a selected hospital of Dehradun at Uttarakhand. A total of 100 samples were selected through purposive sampling technique. A structured knowledge questionnaire was administered through interview technique to assess the knowledge.
Results: The study showed that the mean knowledge score of patients regarding thyroid disorders was 14.04±3.755. The mean percentage was 14.04. There was significant association between social habits, suffered or suffering from thyroid disorders, family history of thyroid disorders, medical history of any medicine intake and previous knowledge regarding thyroid disorders with knowledge score.
Conclusions: From the findings of the study, it was conducted that Out of 100 participants 42% had good knowledge and 7% had poor knowledge, 38% had average knowledge and 13% had very good knowledge about thyroid disorders. There is a need for educational programs to create awareness and improve knowledge regarding thyroid disorders.
Clownselling: an in-depth narrative review on the therapeutic influence of clowning therapy in paediatric and adult cancer treatment and palliative care
Authors: S. Ramya , S. Anantha Krishna B. 
Published: October 2024

Cancer and its treatments impose substantial physical and psychological burdens on patients, underscoring the need for innovative and holistic interventions. This narrative review explores the evolving role of clownselling in paediatric and adult cancer care, tracing its historical progression from entertainment to a therapeutic modality. Recognizing the potential of clowning therapy to address emotional, psychological, and existential challenges, the review systematically assesses its impact on treatment adherence, quality of life, and contributions in palliative care settings. By elucidating the therapeutic process, principles, and goals, it provides a comprehensive understanding of the foundations of clowning therapy. Given its positive influence on well-being, the integration of clowning therapy into interdisciplinary care teams and institutional policies is advocated. Future directions include diversified research, technology integration, standardized protocols and awareness campaigns, ensuring the sustained evolution of clowning therapy in fostering holistic well-being within the intricate tapestry of cancer care.
A constituição política do professor de língua espanhola em formação
Authors: Silva Alana Cristina da , Mendes Galvão Janaína Aguiar , Vieira Barbosa Marinalva 
Published: October 2024

Este trabalho tem como objetivo analisar como o engajamento político do professor de espanhol em formação contribui para a construção de sua identidade, a partir do quadro teórico-metodológico da Linguística Aplicada, no qual mobilizamos os conceitos de representação e de identidade, ademais da noção de política linguística. Trata-se de uma pesquisa documental, posto que nosso corpus é constituído a partir dos dizeres dos bolsistas de Iniciação à Docência presentes nos relatórios de coordenação de área do Programa Institucional de Bolsa de Iniciação à Docência (doravante PIBID). A partir da análise, percebemos que, embora presente, o engajamento político dos professores em formação carece de reflexões teóricas e críticas.
Palavras-Chave: professor; identidade; representação; política linguística.
Variação e mudança no uso de clíticos na fala de estudantes universitários
Authors: Araújo Marinho Alessandra , Melo Rogério Marcelino dos Santos 
Published: October 2024

Esta pesquisa objetiva verificar a ocorrência (ou não) dos clíticos “o”, “os”, “a”, “as”, para a retomada do objeto direto anafórico em português brasileiro na fala de estudantes universitários. Para tanto, aconrou-se na metodologia da Teoria Variacionista (Labov, 2008 [1983]) em comparação aos estudos clássicos de Cunha (1975) e Cegalla (1975) a respeito do emprego dos pronomes clíticos. O percurso do trabalho se deu a partir de levantamento bibliográfico dos pressupostos teóricos-metodológicos, entrevistas, audição e transcrição de fala, discussão e análise dos dados. Os resultados apontaram a não ocorrência no uso dos clíticos para a retomada do objeto direto anafórico, prevalecendo o uso das formas nominais “ele” e “ela” como estratégias anafóricas privilegiadas pelos entrevistados. Desa forma, aponta-se haver uma tendência a variação e mudança, quando do uso dessas formas clíticas.
What Are the Active Effects of the SPS Agreement on the Conservation of Asian Elephants in China during COVID-19 Pandemic
Authors: Wei Jiaqi 
Published: October 2024

<p><span style="font-family: 'Times New Roman';">As</span> COVID-19 pandemic has amplified <span style="font-family: 'Times New Roman';">and i</span>n the context of human-elephant conflict<span style="font-family: 'Times New Roman';">, a sub-topic under the trade and environment topic has given high attention, which is the role of entry and exit animal and plant quarantine in preventing the spread of diseases.Against this background, this study aims to formulate a theoretical insight from SPS Agreement and Conservation of Asian elephants, which are synthesised in the context of COVID-19 pandemic, based on which a conceptual framework is thus proposed.I have used thematic analysis to analyse data collected from textual sources.It is found that when China adopts special SPS measure(s) , even if it does not comply with GATT, it can still apply SPS Agreement to claim an affirmative defense;Furthermore, our finding also suggest that </span>China can <span style="font-family: 'Times New Roman';">benefit from the SPS Agreement as it provides an international frame work for SPS arrangements among countries;In addition, it is interesting to note that as more attention is paid to animal and plant quarantine. Therefore, the room of application of the SPS Agreement will be further expanded.</span><span style="font-family: 'Times New Roman';">With the findings, we contribute to extending the theory of the conservation of Asian elephant and drawing attention to Asian elephants</span>’ <span style="font-family: 'Times New Roman';">sanitary and health.Our findings also provide guidelines for filling the legal gaps in managing the quarantine in China.</span></p>
Learner-Centered Curriculum: A Step Towards English Speaking Skill Improvement of Non-English Teachers
Authors: Dueñas Macías Fredy Alonso 
Published: October 2024

AbstractThis article aims at sharing the results of a small scale research project focused on guiding non-English speaking teachers of a Colombian bilingual school to perform their tasks in English within a school environment, through the implementation of a learner– centered curriculum based on English speaking-oriented workshops. Through theimplementation of this curriculum, it was seemed that the teaching, incorporation and use of some expressions of the English language, such as: greetings and farewells, common classroom expressions,commands and vocabulary, relate d to the specific subjects or topics those teachers teach, in addition to other aspects closely related to those topics, such as pronunciation. This project was conducted at a Colombian bilingual school with a group of 11 teachers in different subjects. Informal conversations with the teachers, interviews, questionnaires and workshops were used to collect the information in this action research study. Findings revealed that through the use of speaking-oriented practice in the workshops, those teachers could reflect on their own foreign language learning process. They became confident and improved their speaking skills. They had the opportunity of working and enhancing their autonomous and cooperative learning skills.Key words: learner-centered curriculum, speaking-oriented workshops, autonomous learning, cooperative learning.