bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversidade de avifauna urbana em Joinville, Santa Catarina
Authors: Valentim Cleiton , Da Silva Mouga Denise Monique Dubet 
Published: June 2018

Visando complementar dados sobre a avifauna urbana de Joinville, foram realizados, de outubro de 2016 a maio de 2018, caminhamentos dentro da área do campus da Universidade da Região de Joinville, com identificação das espécies por visualização, registros fotográficos e playback. Foram levantadas 107 espécies (mais de 17% do total de espécies de Santa Catarina). As famílias Tyranidae e Thraupidae apresentaram a maior riqueza. Nove espécies encontram-se em algum nível de ameaça, 12 são consideradas endêmicas do Brasil e, destas, três são endêmicas de mata atlântica. Verificaram-se espécies migratórias das famílias Accipitridae, Hirundinidae, Motacillidae, Tyrannidae e Vireonidae. Observou-se nidificação das espécies Gallinula galeata e Tyrannus savana, além de indivíduos imaturos de Herpsilochmus rufimarginatus e Pyrocephalus rubinus. Foi registrada a ocorrência de indivíduos de Fluvicola nengeta, espécie rara em Santa Catarina, e de duas espécies exóticas: Estrilda astrild e Passer domesticus. Notou-se a ausência de Sporophila frontalis, apontada para a área em estudos anteriores. Predominaram espécies insetívoras, onívoras e frugívoras, decrescentemente. Os índices de diversidade e equabilidade mostraram valores relevantes. A curva de acumulação de espécies e os estimadores de riqueza indicam maiores valores de diversidade. Áreas de conservação próximas ao campus podem explicar a riqueza avifaunística.
Ursolic and Oleanolic Acids as Potential Anticancer Agents Acting in the Gastrointestinal Tract
Authors: Pięt Mateusz , Paduch Roman 
Published: June 2018

Background:Cancer is one of the main causes of death worldwide. Contemporary therapies, including chemo- and radiotherapy, are burdened with severe side effects. Thus, there exists an urgent need to develop therapies that would be less devastating to the patient’s body. Such novel approaches can be based on the anti-tumorigenic activity of particular compounds or may involve sensitizing cells to chemotherapy and radiotherapy or reducing the side-effects of regular treatment.Objective:Natural-derived compounds are becoming more and more popular in cancer research. Examples of such substances are Ursolic Acid (UA) and Oleanolic Acid (OA), plant-derived pentacyclic triterpenoids which possess numerous beneficial properties, including anti-tumorigenic activity.Results:In recent years, ursolic and oleanolic acids have been demonstrated to exert a range of anticancer effects on various types of tumors. These compounds inhibit the viability and proliferation of cancer cells, prevent their migration and metastasis and induce their apoptosis. Both in vitro and in vivo studies indicate that UA and OA are promising anti-cancer agents that can prevent carcinogenesis at each step. Furthermore, cancers at all stages are susceptible to the activity of these compounds. </P><P> Neoplasms that are formed in the gastrointestinal tract, i.e. gastric, colorectal, pancreatic, and liver cancers, are among the most common and most lethal malignancies. Their localization in the digestive system, however, facilitates the action of orally-administered (potential) anti-cancer agents, making chemopreventive drugs more accessible.In this paper, the anti-tumorigenic effect of ursolic and oleanolic acids on gastric, colon, pancreatic, and liver cancers, as well as the mechanisms underlying this process, are presented.
A Sensitive Microscale HPLC-UV Method for the Determination of Doxofylline and its Metabolites in Plasma: An Adapted Method for Therapeutic Drug Monitoring in Children
Authors: Wu Yue-E , Wu Xiu-Fu , Kan Min , Shi Hai-Yan , Liu Meng-Jie , Dong Qian , Chen Xing-Kai , Huang Xin , Zheng Yi , Zhao Wei 
Published: June 2018

Background:
Doxofylline (DXE) is a novel methylxanthine derivative used in the treatment
of asthma and Chronic Obstructive Pulmonary Diseases (COPD). Therapeutic Drug Monitoring (TDM)
has been proposed in adults, while the adapted analytical method and TDM data are still missing in
children.

Methods:
A highly sensitive and stability indicating High-Performance Liquid Chromatography
(HPLC) method of DXE with caffeine as the internal standard, was developed and validated by separating
its metabolites, β-Hydroxyethyltheophylline (HPE) and Theophylline (TPE). HPLC separation is
achieved on C18 column connected to an ultraviolet detector (276 nm), using acetonitrile and ultra-pure
water in a gradient mode of elution at a flow rate of 0.9 mL/min at 25°C. A liquid-liquid extraction
method using ethyl acetate was developed with a small sample volume of plasma of 50 μL. Trough
concentration was monitored in children receiving DXE therapy.

Results:
The method was linear over the concentration ranges from 0.4-20 µg/mL for DXE, HPE and
TPE, respectively, in plasma. The limits of quantification were 0.4 µg/mL. Intra- and interday coefficients
of variation did not exceed 6.5%, and the accuracy ranged from 94.9% to 112.5%. A total of 39
children (mean age of 1.8 years, range: 0.3-5.7 years) were included. The pediatric patients had detectable
DXE concentrations with a mean value of 1.78 µg/mL (range from 0.49 to 6.36 µg/mL), and HPE
measurable concentrations with a mean value of 0.52 µg/mL (range from 0.40 to 0.82 µg/mL), while the
TPE could not be measured in any patient.

Conclusion:
A sensitive, reliable, and adapted HPLC method has been developed for the simultaneous
analysis of DXE and its metabolites in children. The DXE and its metabolites trough concentrations
showed large inter-individual variability.
Research on Transformer Fault Diagnosis Based on Online Sequential Extreme Learning Machine
Authors: Li Yuancheng , Wang Xiaohan , Zhang Yingying 
Published: June 2018

Background:
Transformer is one of the most important pivot equipment in an electric system
which undertakes major responsibility. Therefore, it is very important to identify the fault of the
transformer accurately and transformer fault diagnosis technology becomes one topic with great
research value.

Methods:
In this paper, after analyzing the shortcomings of traditional methods, we have proposed a
transformer fault diagnosis method based on Online Sequential Extreme Learning Machine (OS-ELM)
and dissolved gas-in-oil analysis. This method has better precision than some commonly used methods
at present. Furthermore, OS-ELM is more efficient than ELM. In addition, we analyze the effect of
different parameter selection on the performance of the model by contrast experiments.

Results:
The experimental result shows that OS-ELM has certain promotion in precision than some
traditional methods and can obviously improve the speed of training than ELM. Besides, it is known
that the number of neurons in the hidden layer and the size of dataset have a great effect on the model.

Conclusion:
The transformer fault diagnosis method based on OS-ELM can effectively identify the
faults and more efficient than ELM.
Use of microsatellite markers to detect heterozygosity in an F2 generation of a black rice and white rice cross
Authors: Kristamtini Kristamtini , Taryono Taryono , Basunanda Panjisakti , Murti Rudi Hari 
Published: June 2018

The aim of this research was to know the heterozygosity of F2 generation from black rice and white rice crossing using microsatellite marker. The research material consisted of F2 Sx G plant population from black rice (S) and white rice Situbagendit (G) crosses, female parent of black rice (S), male parent of white rice (G), chemical and organic fertilizer, chemicals and tools for molecular activity and 3 microsatellite markers related to color properties (RM 220, RM 224 and RM 252). All of plant populations (generation F2, parent female, parent male) were planted in fields up to harvest. Young leaves (30 days after planting) all of plant populations were molecularly analyzed using 3 microsatellite markers (RM 220, RM 224 and RM 252). Stages of this activity include DNA isolation, PCR reaction, and visualization of PCR results using Metaphore Agarose Gel Electrophoresis. The results showed that the percentage of the number of individual plants showing heterozygous pattern in F2 S × G plant generation was 50% (RM 220); 40% (RM 224) and 60% (RM 252), so the RM 252 microsatellite marker was effectively used as a DNA-assisted selection tool on the crossbreed of black rice with white rice.
Identidades em Reinvenção: O Fortalecimento Coletivo de Estudantes Indígenas no Meio Universitário
Authors: Viana Iclicia , Maheirie Kátia 
Published: June 2018

A presença indígena nos espaços acadêmicos tem crescido nos últimos anos, especialmente por conta das politicas de ação afirmativa. A entrada neste universo - espaços historicamente brancos e elitizados - tem produzido fissuras no olhar estereotipado construído sobre povos indígenas e, ao mesmo tempo, tem visibilizado os preconceitos e racismos de nossa sociedade. Neste cenário, a formação superior tem sido reivindicada, cada dia mais, como instrumento de luta necessário para o fortalecimento dos movimentos indígenas. Este texto discute aspectos gerais da presença indígena nas universidades brasileiras, bem como a potência na reinvenção identitária e no fortalecimento de coletivos, marcando a universidade como um novo território de fronteira e de luta que afeta e é afetada pelos povos indígenas. Palavras chave: povos indígenas –– políticas de ação afirmativa – identidade – psicologia e povos indígenas.
A Relação Profissionais de Saúde - Usuários do SUS: Problematizando o Termo "Ajuda"
Authors: Rodrigues Isabela Tellis , Moreira Janine 
Published: June 2018

As relações de poder dentro de uma Estratégia de Saúde da Família (ESF) são reflexos das relações de poder na sociedade, variando de acordo com a formação de cada profissional e, consequentemente, com o status social e acadêmico que cada profissão “detém”. Na equipe mínima da ESF, a medicina está no topo da hierarquia, seguida pelas demais profissões, ainda em uma lógica biologicista e hospitalocêntrica. “Dizer a palavra” ou silenciar está diretamente relacionado com o status profissional. Essa lógica presente na relação entre os profissionais é reproduzida na relação com usuários do serviço. Para superar essa condição, se faz necessário assumir uma posição de dialogicidade nesses espaços, problematizando a “lógica de ajuda”, a qual advém da lógica da compaixão, e que esconde uma noção de superioridade da equipe profissional, e instalando-se, em seu lugar, a lógica da solidariedade, a qual só é possível a partir da corresponsabilização da saúde.
CHARACTERISTICS OF MEAT PRODUCTIIVITY OF CHUB, SQUALIUS CEPHALUS (L., 1758) FROM UPPER AKCAY RIVER, BUYUK MENDERES BASIN (TURKEY)
Authors: Sasi Huseyin , Saidu Mohammed 
Published: June 2018

The meat productivity of
chub (Squalius cephalus) and
the relationship between various organs of the body were determine after catching 153 fish samples from upper
Akcay River, South Aegean Region between June 2012 and May 2013. In this study, the following results are
obtained; percentage of head weight 16.00%, visceral weight 9.90%, fins weigh
6.30% and Meat productivity 67.10%.
Depending on their age between I and VII, chub population meat
efficiency percent was determined as 64.44; 66.86; 70.63; 71.73; 71.31; 71.01
and 67.60 respectively. These results show that meat production increased as
the age increases. It was later proposed to catch fish that have reach maturity
age and are larger than 16,20cm length. Results showed that meat productivity of fish was increased after age
V. in this river.
NEW RECORD OF THE KIZILIRMAK KILLIFISH (Aphanius marassantensis Pfleiderer, Geiger & Herder, 2014) FROM SÜREYYABEY DAM LAKE IN YEŞİLIRMAK BASIN
Authors: Benzer Semra 
Published: June 2018

The aim of this was to quantify morphometries
characteristic of Aphanius marassantensis from Süreyyabey Dam Lake in
2016. Some morphometric characters of
samples were measured. These characteristics were standard length (SL), total
length (TL) body weight (W), head length, preorbital distance, eye diameter,
postorbital distance, head depth, predorsal distance, prepelvic distance,
preanal distance, pectoral fin - pelvic fin distance, pelvic fin - anal fin distance, body depth,
dorsal fin (anterior end) – anal fin distance, dorsal fin (posterior end) –
anal fin distance, postdorsal distance, postanal distance, caudal peduncle
length (dorsal), caudal peduncle length
(ventral), caudal peduncle depth, dorsal
fin base length, anal fin base length, pectoral fin length, pelvic fin length, dorsal fin length, anal
fin length. The SL of 100 individuals ranged from 20 to 38 mm. The TL of individuals
were between 28 and 45 mm, and W ranged between 0.37 and 1.91 g.
Effect of Empagliflozin on Liver Fat in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial (E-LIFT Trial)
Authors: Kuchay Mohammad Shafi , Krishan Sonal , Mishra Sunil Kumar , Farooqui Khalid Jamal , Singh Manish Kumar , Wasir Jasjeet Singh , Bansal Beena , Kaur Parjeet , Jevalikar Ganesh , Gill Harmendeep Kaur , Choudhary Narendra Singh , Mithal Ambrish 
Published: June 2018

OBJECTIVE
Sodium–glucose cotransporter 2 (SGLT-2) inhibitors have been shown to reduce liver fat in rodent models. Data regarding the effect of SGLT-2 inhibitors on human liver fat are scarce. This study examined the effect of empagliflozin (an SGLT-2 inhibitor) on liver fat in patients with type 2 diabetes and nonalcoholic fatty liver disease (NAFLD) by using MRI-derived proton density fat fraction (MRI-PDFF).

RESEARCH DESIGN AND METHODS
Fifty patients with type 2 diabetes and NAFLD were randomly assigned to either the empagliflozin group (standard treatment for type 2 diabetes plus empagliflozin 10 mg daily) or the control group (standard treatment without empagliflozin) for 20 weeks. Change in liver fat was measured by MRI-PDFF. Secondary outcome measures were change in alanine transaminase (ALT), aspartate transaminase (AST), and γ-glutamyl transferase (GGT) levels.

RESULTS
When included in the standard treatment for type 2 diabetes, empagliflozin was significantly better at reducing liver fat (mean MRI-PDFF difference between the empagliflozin and control groups −4.0%; P &lt; 0.0001). Compared with baseline, significant reduction was found in the end-of-treatment MRI-PDFF for the empagliflozin group (16.2% to 11.3%; P &lt; 0.0001) and a nonsignificant change was found in the control group (16.4% to 15.5%; P = 0.057). The two groups showed a significant difference for change in serum ALT level (P = 0.005) and nonsignificant differences for AST (P = 0.212) and GGT (P = 0.057) levels.

CONCLUSIONS
When included in the standard treatment for type 2 diabetes, empagliflozin reduces liver fat and improves ALT levels in patients with type 2 diabetes and NAFLD.
Emoticonların İletişim Aracı Olarak Kullanılmasına Yönelik Öğrenci Tutumlarının İncelenmesi
Authors: SÖNMEZ Hülya 
Published: June 2018

Bu
çalışmada öğrencilerin duygu ve düşüncelerini yazılı olarak ifade etmek için
sıklıkla kullandığı emoticonlara yönelik tutumları incelenmiştir. Yapılan
literatür taraması sonucunda emoticonların son zamanlarda araştırmacıların
dikkatini çekse de bu konunun birçok yönden hâlâ araştırılması gerektiği
belirlenmiştir. Özellikle eğitimde
emoticonların yeri ve öneminin tam olarak aydınlatılmaması bu çalışmayı daha elzem
kılmıştır. Öğrencilerin okul içinde ve dışında kullandıkları emoticonlara
yönelik tutumları belirlemek amacıyla “Anlamlı Suratları (Emoticon) Kullanma
Tutum Ölçeği” (ASK TO)
geliştirildi. Konu alanı uzmanları ve ölçme değerlendirme uzmanlarının görüş ve
önerileriyle tamamlanan ölçeğin pilot uygulaması elli öğrenci ile yapıldı.
Bunun sonucunda gözden geçirilen ölçek ve eki, sekizinci sınıfta eğitim-öğretim
gören 297 öğrenciye uygulandı. Toplanan veriler SPSS 17 istatistik programında
analiz edilerek ölçeğin geçerlilik, güvenirlik ve faktör analizleri yapıldı.
Yapılan güvenirlik analizi sonucunda ölçeğin Cronbach's Alpha değeri (,844)
olarak belirlenmiş olup; ölçeğin oldukça güvenilir olduğu saptandı. Faktör
analizinde ise KMO (,872) ve Barlet testi (p= ,000) anlamlı
bulunarak
faktör homojenliğinin iyi olduğu belirlenmiştir. Araştırmanın sonunda
öğrencilerin emoticonlarla ilgili tutumlarının olumlu olduğu belirlenmiştir. Bu
bulgu sonucunda emoticonların eğitimde yararlı ve etkili bir araç olarak nasıl
kullanılacağı önerilmiştir.
Simulación del Corazón Izquierdo para Aplicaciones en Docencia e Investigación
Authors: Cervino C. Nahuel , Cervino Claudio O. 
Published: June 2018

Un modelo es una descripción lógica de cómo un sistema funciona o cómo se comportan sus componentes. Las herramientas de la modelización dinámica facilitan mucho la construcción de los modelos. El objetivo de este artículo es mostrar el desarrollo y los resultados del funcionamiento de un modelo interactivo de la fisiología del sistema cardiocirculatorio para el uso de estudiantes y otros interesados en la fisiología cardiovascular. El sistema de simulación está compuesto por un modelo simple de cuatro componentes, y simula las siguientes variables y parámetros: a) variaciones del volumen aurícula izquierda (AI) y ventrículo izquierdo (VI); b) variaciones presión en AI, VI y aorta (Ao); c) flujo a través de válvula mitral (VM) y válvula aórtica (VAo), y d) reproduce el “efecto Windkessel” en Ao. Se utilizó el entorno de modelización Extend el cual provee una estructura integrada para la construcción de modelos de simulación y el desarrollo de nuevas herramientas de simulación. El corazón derecho y la circulación pulmonar no son considerados. Los resultados de este modelo simulan las características generales del corazón izquierdo y de la circulación arterial, considerando distintas situaciones fisiológicas y patológicas.
On the Causes of the Decrease of Biodiversity and the Countermeasures
Authors: Yuan Xinqun , Jiang Yanfen , Yan Zhihong 
Published: June 2018

ABSTRACT This paper summarizes the concept, meaning, meaning and current situation of biodiversity. The main reasons for the reduction of biodiversity are as follows: natural, man-made and institutional reasons, among which man-made causes include habitat loss, excessive exploitation of biological resources, environmental pollution and invasion of alien species. The establishment of a system of natural reserve laws, the establishment of alien species management and regulatory system; in the conservation of sustainable use of biological resources; to strengthen international cooperation and action, the establishment of a comprehensive system of protection, , In order to promote China's biodiversity conservation work.
The Influence of Agricultural Water Conservancy Project on Environment
Authors: Yu Lei , Sun Tao 
Published: June 2018

ABSTRACT In recent years, due to the rapid increase of China's economic level, agriculture and industry have developed vigorously, and the demand for electricity has increased accordingly. Water conservancy project construction investment is also increasing, too much water conservancy construction projects will inevitably affect the natural environment, the human environment. China's water conservancy and hydropower construction is facing a diﬃcult task. In terms of environmental impact, compared with other projects, water conservancy and hydropower projects have prominent characteristics: the impact of a wide geographical area, affecting the population, the local social, economic and ecological environment is huge, the external environment on the project also exert a huge impact The At present, the whole society has paid more and more attention to environmental problems, and the environmental quality has become higher and higher. Environmental problems have become one of the restrictive factors in the construction of water conservancy and hydropower projects. As the human environment continues to deteriorate, the public is increasingly concerned about environmental issues and sustainable development. At the same time, people are also aware that the impact of agricultural water conservancy construction on the environment is also twofold, so avoid or mitigate the adverse eﬀects, Fully rational use, is the water conservancy workers in the construction of agricultural water conservancy planning must be carefully studied and to solve the important issues.
Differences in Soil Remediation of Ecological Shelterbelt in Taihu Lake
Authors: Qiu Hongjian , Du Jianmin , Fang Xiaomin , Chen Meifang 
Published: June 2018

In recent years, phytoremediation as a promising ecological restoration technique has emerged. Phytoremediation is a repair method that uses green plants to transfer, contain, or convert contaminants to the environment. Phytoremediation is a heavy metal, organic or radioactive element contaminated soil and water. The results show that the use of plant absorption, volatilization, root filtration, degradation, stability and other effects, can purify soil or water pollutants, to achieve the purpose of purifying the environment, so phytoremediation is a great potential, the development of the clean environment Pollution of green technology. The use of plants to repair contaminated soil is a cheap and durable bioremediation technique. The protection and management of Taihu Lake is an indispensable measure for the protection of Taihu Lake water, and the advantages of phytoremedry investment, low freight and low leakage of pollutants show that its promotion has this unusual significance. This paper expounds the difference of remediation soil between Taihu Lake Ecological Shelter Forest, and the comparison of the soil capacity of the experimental tree species. Second, the correlation between the monitoring projects is discussed.
Research Status and Application of AirSource Heat Pump Technology
Authors: Meng Hongtao , Tang Jihui , Huang Haifeng 
Published: June 2018

Abstract: With the improvement of people's living standards, water heaters almost into the various households. In the energy-saving emission reduction has become the trend of the times today, saving energy and reducing carbon emissions is the most fashionable way of life. Air source heat pump water heaters are increasingly being used in people's lives. It is well known that it has many advantages, safety, energy saving, comfort, environmental protection, but there are some factors that affect its development and promotion. This paper mainly discusses the development history of air source heat pump technology at home and abroad, working principle, working flow, turbo technology at present stage, efficient heat exchange, and the research status of air source heat pump technology, such as new type refrigerant and dual frequency compression frequency conversion, then it discusses the application of air source heat pump technology, has the advantage, and finally discusses its application and the existence of two major problems and suggestions for improvement. Key words:air source heat pump; water heater; energy saving and emission reduction; research status