bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of outcomes in patients on peritoneal dialysis: A 2-year nationwide cohort study
Authors: Abe Masanori , Hamano Takayuki , Hoshino Junichi , Wada Atsushi , Nakai Shigeru , Hanafusa Norio , Masakane Ikuto , Nitta Kosaku , Nakamoto Hidetomo 
Published: March 2019

AbstractThere has been no nationwide study of prognostic factors and outcomes in patients on peritoneal dialysis (PD) in Japan. We conducted a cohort study using data from the nationwide registry of the Japanese Society for Dialysis Therapy. We followed 8,954 prevalent PD patients for 2 years, 2014–2015. Cox proportional hazards regression analysis was used to determine factors that were independently associated with patient survival. Survival rates were compared between patients with and without diabetes after adjusting for potential confounders. During the 2-year study period, 893 (10.0%) of 8,954 patients died, 148 (1.6%) underwent kidney transplantation, and 2,637 (29.4%) were switched to hemodialysis; 5,276 (58.9%) patients were alive at the end of the study period. After multivariate adjustment, older age, longer duration of dialysis, presence of diabetes, cardiovascular comorbidity, use of 2.5% glucose dialysate, higher C-reactive protein and phosphate levels, and a lower serum albumin level were independently associated with increased hazard ratios for all-cause mortality. A combination of PD and hemodialysis was associated with a lower mortality rate. The new-onset cardiovascular event rate was significantly higher in the diabetes group than in the non-diabetes group (P < 0.0001). After adjusting for all variables, the hazard ratio was 1.509 (95% confidence interval 1.029–2.189, P = 0.036) in the diabetes group. Diabetes, older age, longer duration of dialysis, cardiovascular comorbidity, and inflammation were predictors of mortality in patients on PD.
Wireless wide-range pressure sensor based on graphene/PDMS sponge for tactile monitoring
Authors: Kou Hairong , Zhang Lei , Tan Qiulin , Liu Guanyu , Dong Helei , Zhang Wendong , Xiong Jijun 
Published: March 2019

AbstractWe propose a flexible wireless pressure sensor, which uses a graphene/polydimethylsiloxane (GR/PDMS) sponge as the dielectric layer. The sponge is sandwiched between two surfaces of a folded flexible printed circuit with patterned Cu as the antenna and electrode. By adjusting graphene and NH4HCO3 concentrations, a composite with 20% concentration of NH4HCO3 and 2% concentration of graphene as the dielectric layer is obtained, which exhibits high sensitivity (2.2 MHz/kPa), wide operating range (0–500 kPa), rapid response time (~7 ms), low detection limit (5 Pa), and good stability, recoverability, and repeatability. In addition, the sensor is sensitive to finger bending and facial muscle movements for smile and frown, that are transmitted using wireless electromagnetic coupling; therefore, it has potential for a wide range of applications such as intelligent robots, bionic-electronic skin and wearable electronic devices.
The Association of Body Size, Shape and Composition with Vertebral Size in Midlife – The Northern Finland Birth Cohort 1966 Study
Authors: Oura Petteri , Nurkkala Marjukka , Auvinen Juha , Niinimäki Jaakko , Karppinen Jaro , Junno Juho-Antti 
Published: March 2019

AbstractSmall vertebral size increases the risk of osteoporotic vertebral fractures. Obese individuals have larger vertebral size and potentially lower fracture risk than lean individuals, but scarce data exist on the association between vertebral size and anthropometric measures beyond height, weight, and body mass index (BMI). Here, we evaluated several anthropometric measures (height, weight, BMI, waist circumference, hip circumference, waist-to-hip ratio [WHR], waist-to-height ratio [WHtR], fat mass [FM], lean body mass [LBM], percentage FM [%FM], percentage LBM [%LBM]) as predictors of vertebral cross-sectional area (CSA). We used a representative sample from the Northern Finland Birth Cohort 1966 (n = 1087), with anthropometric measurements from the ages of 31 and 46, bioimpedance analysis from the age of 46, and lumbar magnetic resonance imaging from the age of 46 years. In our data, height and LBM correlated most strongly with vertebral CSA among both sexes (0.469 ≤ r ≤ 0.514), while WHR, WHtR, %FM, and %LBM had the weakest correlations with vertebral CSA (|r| ≤ 0.114). We conclude that height and LBM have the highest, yet only moderate correlations with vertebral size. High absolute LBM, rather than FM or abdominal mass accumulation, correlates with large vertebral size and thus potentially also with lower osteoporotic vertebral fracture risk.
Integrated synthesis of nucleotide and nucleosides influenced by amino acids
Authors: Suárez-Marina Irene , Abul-Haija Yousef M. , Turk-MacLeod Rebecca , Gromski Piotr S. , Cooper Geoffrey J. T. , Olivé Andrea Olivé , Colón-Santos Stephanie , Cronin Leroy 
Published: March 2019

AbstractResearch on prebiotic chemistry and the origins of nucleic acids and proteins has traditionally been focussed on only one or the other. However, if nucleotides and amino acids co-existed on the early Earth, their mutual interactions and reactivity should be considered explicitly. Here we set out to investigate nucleotide/nucleoside formation by simple dehydration reactions of constituent building blocks (sugar, phosphate, and nucleobase) in the presence of different amino acids. We demonstrate the simultaneous formation of glycosidic bonds between ribose, purines, and pyrimidines under mild conditions without catalysts or activated reagents, as well as nucleobase exchange, in addition to the simultaneous formation of nucleotide and nucleoside isomers from several nucleobases. Clear differences in the distribution of glycosylation products are observed when glycine is present. This work demonstrates that reaction networks of nucleotides and amino acids should be considered when exploring the emergence of catalytic networks in the context of molecular evolution.
LQAC-5: The fifth release of the Large Quasar Astrometric Catalogue
Authors: Souchay J. , Gattano C. , Andrei A. H. , Souami D. , Coelho B. , Barache C. , Taris F. , Secrest N. , Berthereau A. 
Published: March 2019

Context. In addition to their great astrophysical interest, quasars represent quasi-ideal reference objects in the celestial sphere with, a priori, a lack of significant proper motion. Since the fourth release of the Large Quasar Astrometric Catalogue (LQAC-4), a large number of quasars have been discovered, in particular those coming from the DR14Q release of the SDSS. With the advent of the Gaia Data Release 2 (DR2), it is now also possible to fold in extremely accurate quasar positions.
Aims. Following the same procedure as in the previous releases of the LQAC, our aim is to compile the large majority of the recorded quasars, with their best estimated coordinates and substantial information about their physical properties such as the redshift, multi-bands apparent, and absolute magnitudes. Emphasis is given to the results of the cross-matches with the Gaia DR2 catalogue, which considerably increases the positional accuracy.
Methods. New quasars from the SDSS DR14Q release were cross-matched with the precedent LQAC-4 compilation with a 1″ search radius, which leads to 149 084 objects not present in the previous LQAC-4 release. Another cross-match was done with the Gaia DR2 catalogue, which enables us to considerably improve the positioning of these objects. For the first time, parallaxes and proper motions from the DR2, when available, are added to our compilation. Furthermore, a cross-identification of the LQAC-5 with the AllWISE survey gives additional mid-infrared information for an important percentage of objects.
Results. Our final catalogue, namely the LQAC-5, contains 592 809 quasars. This represents roughly a 34% increase with respect to the number of objects recorded in the LQAC-4. Among them, 398 697 objects were found in common with the Gaia DR2, within a 1″ search radius. That corresponds to 67.26% of the whole population of the compilation.
Conclusion. The LQAC-5 delivers a nearly complete catalogue of spectroscopically confirmed quasars (including a small proportion of 14 126 compact AGN’s) to the astronomical community, with the aim of giving their best equatorial coordinates with respect to the ICRF2 and with exhaustive additional information. For more than 50% of the sample, these coordinates are extracted from the very recent Gaia DR2.
Arabic translation and validation of three knee scores, Lysholm Knee Score (LKS), Oxford Knee Score (OKS), and International Knee Documentation Committee Subjective Knee Form (IKDC)
Authors: Ahmed Khamis Mohamed , Said Hatem G. , Ramadan Eslam Karam Allah , Abd El-Radi Mohamed , El-Assal Maher A. 
Published: March 2019

Aim of the work: Translation and validation of three commonly used knee scores to Arabic language: the Lysholm Knee Score (LKS), the Oxford Knee Score (OKS), and IKDC Subjective Knee Form.
Methods: Our work focused on translation and validation of the LKS, OKS and IKDC. Construct validity was assessed by comparing the LKS, OKS, and IKDC Subjective Knee Form and previous Arabic translated version of Knee injury and Osteoarthritis Outcome Score (KOOS). Test−retest reliability, internal consistency, and construct validity were assessed, using Intraclass Correlation Coefficient (ICC), Cronbach's alpha, and Pearson correlation coefficient (r).
Results: Reliability was excellent for the Arabic IKDC subjective form (0.95), while the Arabic LKS and the Arabic OKS were good: 0.8 and 0.85, respectively. The Cronbach's ά was excellent for the Arabic LKS and Arabic OKS: 0.9 and 0.90, respectively, while the Arabic IKDC subjective form was good (0.89). Construct validity was high for the Arabic LKS and the Arabic OKS: 0.7 and 0.913, respectively, while the Arabic IKDC was moderate (0.4) in cases of ACL and meniscus injuries and mild (0.18) in cases of osteoarthritis.
Conclusion: Arabic LKS and Arabic OKS were reliable and valid scores for patients complaining of ligamentous injuries, meniscus injuries, and osteoarthritis to be used for Arabic-speaking people, while the Arabic IKDC had excellent reliability and mild validity in cases of osteoarthritis and moderate validity in cases of ACL and meniscus injuries.
Wie laut ist das denn?!
Authors: Fritzsche Christian , Heinicke Tobias , Siegel Daniel 
Published: March 2019

ZusammenfassungTelefonläuten, Klimaanlagen, das Schließen von Türen – all das verursacht Lärm.
Auf Intensivstationen kommen dann noch die Geräuschpegel und Alarme der diversen
Überwachungsgeräte hinzu, und auch das Personal und die Patienten selbst
verursachen Lärm. Wird er zu groß, hat er nicht nur negative Auswirkungen auf
den Genesungsprozess der Patienten. Auch das Pflegepersonal leidet. Lärm
beeinträchtigt nicht nur ihre Konzentration und Aufmerksamkeit, sondern kann
auch ihre Gesundheit dauerhaft schädigen.
Alles gleichzeitig und trotzdem gut? (Teil
1)
Authors: Zoller Richard , Lange Kathrin , Nowak Miriam , Lauer Wolfgang 
Published: March 2019

ZusammenfassungDer Arbeitsbereich von Intensivpflegenden beinhaltet neben der professionellen
Pflege der Patienten auch den zuverlässigen Umgang mit Technik- und
Medizinprodukten aller Art. Die anfallenden Aufgaben sind dabei meist wenig
planbar, schneller Aufgabenwechsel und das gleichzeitige Erledigen verschiedener
Tätigkeiten sind charakteristisch für das Tätigkeitsfeld. Welche Auswirkungen
aber hat dieses Multitasking auf die Sicherheit im Umgang mit
Medizinprodukten?
Kopfschmerzen – Update 2018
Authors: Diener Hans-Christoph , Gaul Charly , Holle-Lee Dagny , Jürgens Tim P. , Kraya Torsten , Kurth Tobias , Nägel Steffen , Neeb Lars , Straube Andreas 
Published: March 2019

ZusammenfassungDie Kopfschmerzforschung macht Fortschritte. Dies zeigt sich an der großen Zahl
von Publikationen zur Epidemiologie, Pathophysiologie, Akuttherapie und
Prophylaxe von Kopfschmerzen. Die vorliegende Übersicht referiert die
wichtigsten Studien zu Kopfschmerzen aus dem Zeitraum 2017 bis Juni 2018. Die
Auswahl der referierten Studien ist subjektiv und erfolgte nach der Einschätzung
der Autoren.
Free Flap Reconstruction of the Maxilla
Authors: Vincent Aurora , Burkes Jason , Williams Fayette , Ducic Yadranko 
Published: March 2019

AbstractTumors of the maxilla and midface are some of the most difficult to manage, not only in terms of treatment but also in terms of achieving acceptable orofacial reconstruction. Today, free flaps dominate the reconstructive field. Many patients can achieve successful reconstruction after free flap transfer with a return of intelligible speech, a regular diet, and acceptable cosmesis. Herein, the authors review free flap reconstruction of the maxilla, with a focus on the classifications of defects, when obturators are appropriate, types and sources of free flaps, and complications for which to beware.
Surgical Treatment of Meniscal RAMP Lesion
Authors: Gülenç Barış , Kemah Bahattin , Yalçın Sercan , Sayar Şafak , Korkmaz Oğuzhan , Erdil Mehmet 
Published: March 2019

AbstractRAMP lesion, defined as peripheral detachment lesion of posterior horn of medial meniscus, has been shown to accompany anterior cruciate ligament (ACL) ruptures and is thought to play an important role in the knee joint stability. In this study, we aimed to present results of postoperative knee function scores and patient satisfaction after surgical repair of RAMP lesion. We included 15 patients who had undergone knee arthroscopy due to RAMP lesion in 2017. We recorded demographic data, diagnosis, pre- and postoperative International Knee Documentation Committee and Tegner–Lysholm scores of all patients. In this study, we included 15 patients: the number of male and female patients was eight and seven, respectively. The mean age of patients was 26.8 (18–35). Associated injuries included ACL rupture in 12 patients, additional medial meniscus lesion in 3 patients, lateral meniscus lesion in 3 patients, and superomedial patellar plicae syndrome in 2 patients. All patients had the same postoperative rehabilitation protocol. Mean preoperative Tegner–Lysholm knee score was 64.4 (53–75), while it was 82.5 (75–89) postoperatively, and mean preoperative and postoperative Visual Analogue Scale score at last postoperative follow-up were 5.26 (2–8) and 1.06 (0–2), respectively. All differences were found to be statistically significant. Meniscal RAMP lesions are commonly associated with ACL ruptures. RAMP repair significantly increases postoperative knee function scores and patient satisfaction following ACL reconstruction.
Maternal and Perinatal Outcomes in Pregnant Women with Cystic Fibrosis
Authors: Osmundo Junior Gilmar de Souza , Athanazio Rodrigo Abensur , Rached Samia Zahi , Francisco Rossana Pulcineli Vieira 
Published: March 2019

Objectives To assess the perinatal and maternal outcomes of pregnant women with cystic fibrosis (CF) and severe lung impairment.Methods This was a series of cases aiming to review the maternal and fetal outcomes in cases of singleton pregnant women with a diagnosis of CF. We have included all of the cases of singleton pregnancy in patients with CF who were followed-up at the obstetrics department of the Medical School of the Universidade de São Paulo, between 2003 and 2016. The exclusion criteria were the unattainability of the medical records of the patient, and delivery at other institutions. A forced expiratory volume in 1 second < 50% was considered as severe lung impairment. We have also analyzed data regarding maternal hospitalization and respiratory exacerbations (REs).Results Pregnant women with CF and severe lung impairment did not present an association with spontaneous prematurity, fetal growth restriction or fetal demise. All of the cases involved multiple RE episodes requiring antibiotic therapy. The median (range) of events per patient was of 4 (2–4) events.Conclusion Cystic fibrosis patients with severe lung impairment may achieve successful term pregnancies. However, pregnancies of women with CF are frequently complicated by REs, and this population may require hospital admission during the course of the pregnancy. Cystic fibrosis patients should be followed by a specialized team with experience in treating respiratory diseases.
Endovascular Aneurysm Repair Complicated with Type Ia Endoleak and Presumable Infection Treated with a Fenestrated Endograft
Authors: de Niet Arne , van Schaik Paul , Saleem Ben , Zeebregts Clark , Tielliu Ignace 
Published: March 2019

AbstractAn 81-year-old patient presented to the emergency room 5 years after infrarenal endovascular aneurysm repair, with a Type Ia endoleak and a presumable infection of the graft material with Listeria monocytogenes. He was treated with a custom-made fenestrated endograft to seal the endoleak and lifelong antibiotic therapy to suppress the infection. Full explantation of graft material is not always preferable, and endovascular treatment combined with antibiotic suppressive therapy is in some cases an appropriate alternative.
Public Perception of Facial Fillers
Authors: Hojjat Houmehr , Raad Richard , Lucas Jordyn , Mir Mohammad , Smith Brendan , Carron Michael , Zuliani Giancarlo 
Published: March 2019

AbstractThere has been widespread coverage of cosmetic procedures, particularly facial fillers, as minimally invasive options for facial rejuvenation. The authors' objective was to characterize news media's coverage of facial fillers and its role in shaping public perception of these products over the past decade. Public view plays a significant role in policymaking, assisting patient communication, and addressing preconceived notions. Google News was searched for online news coverage related to “facial fillers” from 2008 to 2017. News articles from various sources were reviewed and analyzed with multiple objectives including complications listed, advantages, disadvantages, physician specialties, overall theme of the articles as positive, negative, or neutral and other parametrics. A chi-square test was used for statistical analysis. Of 426 articles meeting inclusion criteria, international news (20.4%), tabloids (18.8%), online health sites (18.3%), and national news (16.9%) were represented. Of articles containing adequate information, coverage was 44.7% positive, 29.9% neutral, and 26.1% negative with no significant change from 2008 to 2017. In addition, 46.0% of papers discussed complications including vascular injury and blindness associated with fillers, with significant increase by 2017 (p < 0.05). Facial fillers media coverage was overall positive, with broad coverage at both national and international levels. Complications were discussed often, and although vascular injury and vision damage are rare complications of fillers, they were frequently cited, potentially leading the public to believe they occur frequently. There were also significant concerns in the news media about greater regulation of products used as facial fillers, and practitioners administrating them. Altogether, these findings provide a comprehensive overview of patient perception and expectations of an increasingly popular and expanding cosmetic procedure.
Community-Acquired Pneumonia Due to Virus and Mycoplasma pneumoniae Infection in Children Younger than 5 Years
Authors: Sun Huiming , Zhu Wenqing , Chen Zhengrong , Ji Wei , Hao Chuangli , Xinxing Zhang , Wenjing Gu , Wang Yuqing 
Published: March 2019

AbstractThe purpose of this study was to determine the clinical features of viral pathogens and Mycoplasma pneumoniae in children hospitalized with community-acquired pneumonia (CAP). M. pneumoniae infection was diagnosed by both serology and polymerase chain reaction (PCR). Respiratory viruses were detected by direct immunofluorescence or PCR. Medical records of children younger than 5 years diagnosed with 5-day-old CAP were reviewed. Viral pathogens and/or M. pneumoniae were detected in 388 (15.59%) children in the following three groups: viral monoinfection (n = 321), M. pneumoniae with viral coinfection (n = 17), and M. pneumoniae monoinfection (n = 50). M. pneumoniae monoinfection was characterized by older age, fever, higher neutrophil count, and chest X-ray showing lobar consolidation. Wheezing was more common in children with viral infections. Elevated alanine aminotransferase and aspartate aminotransferase were commonly seen in children with Mycoplasma infections. The median symptom duration in children with viral coinfection was shorter than in the other two groups (both p < 0.05). M. pneumoniae and respiratory viruses are important etiologic agents for CAP in children younger than 5 years, with characteristic clinical features. M. pneumoniae and viral coinfection are associated with shorter duration of symptoms before admission.
I Want to Break Free
Authors: Miteva Evelina 
Published: March 2019

Abstract
Albertus Magnus is known for his rational approach to explaining various phenomena; a method that would be acquired and
applied by his pupil Thomas Aquinas as well. In this paper, I focus on the concept of freedom, i. e., on the question of what it is that
constitutes the freedom of free will in the account of Albert the Great. I investigate this question from the perspective of natural
philosophy, a field that Albert was particularly interested in. In the first part of the paper, I study Albert’s definition of free will and
its implications as they are tackled in De homine, De anima, and Ethica. Albert regards free will as a
capacity of the rational soul, capable of choosing from opposites. Albert confronts the definitions of free will presented by Augustine,
Bernard of Clairvaux, and Anselm of Canterbury, and in each of these cases he advances his argument from the perspective of psychology. In
the second part of the paper, I identify the topics in which the general definition of free will is applied in a naturalistic context. Those
are the debates on fate and free will, on the question whether animals have free will and, finally, on natural circumstances such as age or
gender, limiting the freedom of free will. Subsequently, I aim at expounding Albert’s balanced, yet not tension-free position in the debate
between determinism and free action. Although several extensive studies on fate in Albert have been produced, the problem of free choice in
Albert’s works remains surprisingly understudied. The present paper intends to open a path for further research and debates on this relevant
topic.
Aquinas’ Balancing Act
Authors: Klima Gyula 
Published: March 2019

Abstract
In this paper, I will primarily argue for the consistency of Aquinas’ conception, according to which the human
soul, uniquely in God’s creation, is both the inherent, material, substantial form of the human body, and the subsistent
immaterial substance underlying the immaterial operations of its immaterial, rational powers, namely, intellect and will. In this
discussion, I will point out that typical challenges to Aquinas’ conception usually rely on semantic or ontological assumptions
that can plausibly be denied in Aquinas’ own conceptual framework. Since the issue of consistency merely assumes the less than
self-evident claim of the immateriality of the human intellect, I will also provide a brief sketch of what I take to be Aquinas’
most promising proof of this claim.