bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Mechanical Damages and Storage Conditions on Quality of Markies cv. Potatoes for Processing
Authors: Gonçalves Dreice Nascimento , Soares Luciana Gomes , Pereira Ariana Mota , Silva Ramos Paula Acácia , Guimarães Maria Eduarda Da Silva , Finger Fernando Luiz 
Published: May 2019

Aims: Evaluate whether mechanical damage and storage conditions affect the quality of the ‘Markies’ potato for processing.
Study Design: The experimental design was the completely randomized, in the scheme of split-plots. The plots were composed of treatments with and without mechanical damage and the subplots were made up by the evaluation times, with 5 replicates, where the experimental unit was composed of 2 tubers.
Place and Duration of Study: Tubers of the ‘Markies’ cultivar from the producing region of Perdizes, State of Minas Gerais, were planted in June 2016 and harvested in October 2016.
Methodology: The tubers were stored for 2 months at 8°C, and further divided into treatment with damage, in which the tubers were subjected to impact and abrasion; and control treatment, in which the tubers were not damaged. After that, they were stored at 28°C and evaluated for their loss of loss of accumulated fresh mass (FML), total soluble sugar (TSS), reducing sugar (RS), non-reducing sugar (NRS) and color after frying in the periods of 0, 12, 24, 36 and 48 h after being placed at room temperature.
Results: The mechanical damage in the tubers increased FML, however, it did not affect the content of TSS, NRS, RS and color after frying. Increases were observed in the content of TSS and NRS after 12 h of evaluation. Grade 2 was assigned to the coloring scale after frying for the tubers regardless of treatment or evaluation period.
Conclusion: Mechanical damage increases the FML and the ‘Markies’ cultivar is suitable for the industry of pre-fried potato processing even under the occurrence of mechanical damage and exposure to high temperatures.
Comparative Efficacy of 50% Trichloroacetic Acid Solution with 10% Potassium Hydroxide Solution in the Treatment of Plane Warts
Authors: Yaghoobi Reza , Pazyar Nader , Maleki Bahareh 
Published: May 2019

Background: Warts are very common disorders. Plane warts are caused by Human Papilloma Virus (HPV) occurring mostly in children and young adults. Among the treatment modalities, topical application of trichloroacetic acid (TCA) is age old. Potassium hydroxide (KOH) has a keratolytic effect on virus-infected cells.
Aims: To compare the safety and efficacy of topical 10% KOH solution with 50% TCA solution in the treatment of plane warts.
Materials and Methods: Sixty-four consecutive patients with plane warts were randomly assigned into two groups of thirty-two patients. Group A received 10% KOH solution and group B received 50% TCA solution once weekly until the complete clearance of warts in a maximum period of 12 weeks.
Results: In group under treatment with 10% KOH, 24 patients (75.0%) complete response, 5 patients (15.6%) moderate response, 2 patients (6.3%) mild response, and 1 patient (3.1%) had no response. In group under treatment with 50% TCA, 28 patients (87.5%) showed complete response, 2 patients (6.3%) moderate response, 2 patients (6.3%) mild response. Statistically no significant difference was found between the therapeutic response to 10% KOH and 50% TCA (P=0.41).
Conclusion: 10% KOH was found to be equally effective in the treatment of plane warts compared to 50% TCA with the advantage of fewer side effects.
ANALISIS KESALAHAN PENGGUNAAN TANDA BACA BAHASA TIONGHOA DALAM MENULIS DAN MEMBACA OLEH MAHASISWA KELAS MENENGAH DAN ATAS SASTRA TIONGHOA UNIVERSITAS KRISTEN PETRA
Authors: Wijaya Filona Sagita , Kurniawan Budi , Zhu Shuiqing 
Published: May 2019

Berdasarkan pada penelitian Zeng (2017) telah melakukan penelitian terhadap beberapa hasil penelitian sebelumnya pada tahun 2002 sampai 2016 mengenai analisis kesalahan tanda baca. Dalam penelitian tersebut ditemukan “ isi penelitian, cara penelitian dilakukan berulang- ulang” , mayoritas data penelitian berupa karangan dari mahasiswa, penelitian yang bersifat eksperimental sangat sedikit (hanya ada satu penelitian). Penulis menggunakan data penelitian dari karangan mahasiswa, proposal mahasiswa dan soal tes kecil, membuat hasil penelitian menjadi lebih objektif, juga menghasilkan penelitian yang bersifat eksperimental. Pertama, penulis melakukan perhitungna pada analisis kesalahan penggunaan tanda baca, kemudian tahap selanjutnya menggolongkan kesalahan tersebut dan menjelaskan letak kesalahan pada kalimat yang salah. Untuk mengetahui mengenai korelasi pemahaman penggunaan tanda baca yang berkaitan dengan kemampuan membaca dan menulis, penulis menggunakan Pearson Correlation . Hasilnya adalah, kesalahan fungsi dalam penggunaan tanda baca tanda baca koma terhadap kemampuan menulis dan membaca memiliki korelasi yang kuat, sedangkan tanda baca lainnya tidak memiliki korelasi.
Long‐Term Spinal Mobility in Ankylosing Spondylitis: A Repeated Cross‐Sectional Study
Authors: Sundström Björn , Ljung Lotta , Hörnberg Kristina , Wållberg‐Jonsson Solveig 
Published: May 2019

ObjectiveTo evaluate the course of impaired spinal mobility in patients with long‐standing well‐defined ankylosing spondylitis (AS).MethodsData from 232 patients with AS (186 men, 46 women) and 3,849 clinical measurements performed between February 1980 and June 2016 were analyzed. Lateral spinal flexion (LSF), the 10‐cm Schober test, chest expansion (CE), and cervical rotation measurements were stratified by disease duration at 10‐year intervals and compared with published age‐ and height‐adjusted spinal mobility reference intervals as well as with fixed reference values commonly used in clinical practice.ResultsAfter 10 years of AS, most patients exhibited at least 1 measurement, most commonly LSF, that was under the 2.5th percentile of the adjusted reference interval (53% of men, 65% of women). In all measurements except CE, there were significant linear increases in the proportion of patients during 40 years of disease duration who exhibited impaired mobility. Measured LSF values <2.5th percentile (mean 14.8 cm) after 10 years were associated with further spinal mobility impairments later in the disease course. Fixed reference values yielded higher proportions of patients with impaired mobility compared with adjusted reference intervals.ConclusionImpaired spinal mobility in AS is common after a 10‐year disease duration. LSF below the 2.5th percentile at 10 years appeared to be associated with a worse prognosis. Fixed reference values overestimated spinal mobility impairments in AS and should be avoided.
Patterns of Depressive Symptoms Before and After Surgery for Osteoarthritis: A Descriptive Study
Authors: Power J. Denise , Kudesia Prtha , Nadeem Alina , Perruccio Anthony V. , Sundararajan Kala , Mahomed Nizar N. , Rampersaud Y. Raja , Gandhi Rajiv 
Published: May 2019

ObjectiveTo examine patterns of depressive symptoms before and over the year following osteoarthritis (OA) surgery, stratified by joint and postsurgical outcome.MethodsParticipants were hip (n = 287), knee (n = 360), and lumbar spine (n = 100) OA patients scheduled for joint replacement or decompression surgery with or without fusion. One pre‐ and 4 postsurgery questionnaires were completed. Depressive symptoms were quantified using the Hospital Anxiety and Depression Scale (HADS). One‐year outcomes were based on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain scores for hip and knee patients and Oswestry Disability Index (ODI) scores for spine patients and were categorized as “worse” (top score tertile) vs. “better” outcomes (first, second tertiles). Plots over time were generated by joint and outcome: 1) mean pain/disability and depression scores and 2) percentage of patients meeting HADS cut‐off for depression “caseness,” reporting depression diagnosis and treatment.ResultsThere were notable decreases in depression scores for patients with better outcomes. For those with worse outcomes, decreases were smaller for hip patients and were not significant for knee and spine patients. Among those with poorer outcomes, 25% of spine and knee patients were depression “cases” pre‐ and postsurgery; an additional 16% of spine and 10% of knee patients developed new “caseness” postsurgery. The proportion of these patients deemed depression cases by score was much higher than the proportion reporting diagnosis/treatment.ConclusionAlthough depressive symptoms decrease overall in OA patients postsurgery, degrees of change vary by joint and surgical outcome. Greater attention to mental health postsurgery is warranted and may lead to improved surgical outcomes, particularly among knee and spine patients.
Systematic Analysis of the Improvements in Magnetic Resonance Microscopy with Ferroelectric Composite Ceramics
Authors: Moussu Marine A. C. , Ciobanu Luisa , Kurdjumov Sergej , Nenasheva Elizaveta , Djemai Boucif , Dubois Marc , Webb Andrew G. , Enoch Stefan , Belov Pavel , Abdeddaim Redha , Glybovski Stanislav 
Published: May 2019

AbstractThe spatial resolution and signal‐to‐noise ratio (SNR) attainable in magnetic resonance microscopy (MRM) are limited by intrinsic probe losses and probe–sample interactions. In this work, the possibility to exceed the SNR of a standard solenoid coil by more than a factor‐of‐two is demonstrated theoretically and experimentally. This improvement is achieved by exciting the first transverse electric mode of a low‐loss ceramic resonator instead of using the quasi‐static field of the metal‐wire solenoid coil. Based on theoretical considerations, a new probe for microscopy at 17 T is developed as a dielectric ring resonator made of ferroelectric/dielectric low‐loss composite ceramics precisely tunable via temperature control. Besides the twofold increase in SNR, compared with the solenoid probe, the proposed ceramic probe does not cause static‐field inhomogeneity and related image distortion.
Reactive Gelation Synthesis of Monodisperse Polymeric Capsules Using Droplet‐Based Microfluidics
Authors: Yang Tianjin , Cingolani Alberto , Casalini Tommaso , Aribia Abdessalem , Klaue Antoine , Wu Hua , Stavrakis Stavros , de Mello Andrew , Morbidelli Massimo 
Published: May 2019

AbstractA novel methodology, combining reactive gelation and droplet‐based microfluidics, is described for the synthesis of rigid, porous, and hollow polymeric nanoparticles (NPs). The precursors of such capsules are microfluidically generated latex droplets, with diameters tunable between 20 and 100 µm. The conversion of latex droplets to polymeric capsules involves two steps, namely self‐migration and gelation of the NPs toward the oil–water interface to form a solid‐like shell, and then postpolymerization to covalently fix the shell structure. The hollow structure of the capsules results from the interaction between negatively charged NPs inside the droplet and positive charges present on fluorosurfactant at the droplet interface. Significantly, the porosity and average pore size in the capsule shell can be controlled through variation of the initial NP concentration in the droplet. Based on the analysis of diffusion of fluorescent molecules of known size, it is shown that penetration of molecules into the internal volume of the capsules increases as the initial NP concentration in the droplet decreases, thus the porosity of the formed shell increases. This novel synthetic methodology defines a powerful tool in the generation of hollow capsules of controlled size and morphology, and has significant application in material sciences.
A Dual‐Gate InGaZnO4‐Based Thin‐Film Transistor for High‐Sensitivity UV Detection
Authors: Chen Po‐Hsun , Tsao Yu‐Ching , Chien Yu‐Chieh , Chiang Hsiao‐Cheng , Chen Hua‐Mao , Lu Ying‐Hsin , Shih Chih‐Cheng , Tai Mao‐Chou , Chen Guan‐Fu , Tsai Yu‐Lin , Huang Hui‐Chun , Tsai Tsung‐Ming , Chang Ting‐Chang 
Published: May 2019

AbstractUV‐sensing devices have received significant recent attention for applications in areas such as human health, fire detection, and optical communication. One key factor for product commercialization is determining the optimal materials that allow for integration of excellent UV‐sensing properties with compatibility with industrial fabrication processes. However, current UV sensors often fail to achieve this due to either mismatched materials or a device that must be excessively large in order to produce enough photocurrent for UV detection. The UV‐light‐sensing properties of an amorphous InGaZnO4 (IGZO) thin‐film transistor with a dual‐gate structure and relatively small device size (width/length = 50 µm/10 µm) that achieves high sensitivity through a threshold‐voltage‐(Vth)‐adjustment method is proposed. Comparing the drain currents under UV exposure to those under darkened conditions indicates that the ratio between the photoinduced and dark current reaches 106. Furthermore, the UV sensitivity of the dual‐gate transistors can be adjusted by varying the bottom gate voltage, with each pixel of the sensor then being read out separately via scan line pulses. This allows the dual‐gate a‐IGZO transistor to be used for high‐performance UV sensing while being effectively integrated in display applications.
Porous Particle‐Based Inkjet Printing of Flexible Fluorescent Films: Enhanced Sensing Performance and Advanced Encryption
Authors: Li Min , Liu Jianfei , Shang Congdi , Liu Ke , Qi Yanyu , Miao Rong , Fang Yu 
Published: May 2019

AbstractInnovative design and fabrication of fluorescent films are key steps in the development of film‐based fluorescent sensors, where both sensing unit and substrate are crucial to the performance of the films. To improve sensing performance via increasing mass transfer, hierarchical porous particles are chosen as substrate. NBDCOOH is adopted as a representative sensing fluorophore, and is immobilized onto the particles via physical adsorption. Dispersing the fluorescent particles into a mixture of ethanol and glycerol results in a fluorescent ink. It is demonstrated that the fluorescence of the film obtained from this particle‐based ink is more than 45 times stronger than that from pure NBDCOOH solution. In addition, the particle‐based film shows much improved photochemical stability and enhanced sensing performance. Owing to its printability, it can be used to generate complex patterns, which can be used for advanced information encryption.
Squid‐Inspired Smart Window by Movement of Magnetic Nanoparticles in Asymmetric Confinement
Authors: Yang Junseok , Lee Hyunggyu , Heo Seong Gil , Kang Sunghwan , Lee Hyemin , Lee Cho Hee , Yoon Hyunsik 
Published: May 2019

AbstractThe camouflage used by cephalopods is an interesting topic in biomimetics. Squid, part of the cephalopod family, have transformable skin that can be made transparent or darkened through control of the light‐absorption area. This is achieved using a muscular structure. A smart‐window scheme inspired by this is developed. Magnetic nanopigments dispersed within an asymmetric pyramidal array are used and the light‐absorption area is manipulated through use of a magnetic field. Refractive‐index‐matched liquids are used as a dispersion media to avoid refraction at the interface. The transparency hysteresis (ON/OFF ratio) performance depends on the ratio of magnetic nanoparticles and the dispersive fluid and a model is derived to explain this. In addition, a 3D‐printed structure is proposed and demonstrated for better performance.
Bioinspired Polydopamine‐Based Resistive‐Switching Memory on Cotton Fabric for Wearable Neuromorphic Device Applications
Authors: Bae Hagyoul , Kim Daewon , Seo Myungsoo , Jin Ik Kyeong , Jeon Seung‐Bae , Lee Hye Moon , Jung Soo‐Ho , Jang Byung Chul , Son Gyeongho , Yu Kyoungsik , Choi Sung‐Yool , Choi Yang‐Kyu 
Published: May 2019

AbstractFabric‐based electronic textiles (e‐textiles) have been investigated for the fabrication of high‐performance wearable electronic devices with good durability. Current e‐textile technology is limited by not only the delicate characteristics of the materials used but also by the fabric substrates, which impose constraints on the fabrication process. A polydopamine (PDA)‐intercalated fabric memory (PiFAM) with a resistive random access memory (RRAM) architecture is reported for fabric‐based wearable devices, as a step towards promising neuromorphic devices beyond the most simple. It is composed of interwoven cotton yarns. A solution‐based dip‐coating method is used to create a functional core–shell yarn. The outer shell is coated with PDA and the inner shell is coated with aluminum (Al) surrounding the core yarn, which serves as a backbone. The Al shell serves as the RRAM electrode and the PDA is a resistive‐switching layer. These functional yarns are then interwoven to create the RRAM in a lattice point. Untreated yarn is intercalated between adjacent functional yarns to avoid cell‐to‐cell interference. The PiFAM is applied to implement a synapse, and the feasibility of a neuromorphic device with pattern recognition accuracy of ≈81% and the potential for application in wearable and flexible electronic platforms is demonstrated.
Generation of Spin‐Dependent Accelerating Beam with Geometric Metasurface
Authors: Wang Haoyu , Du Jing , Wang Han , Lu Yonghua , Wang Pei 
Published: May 2019

AbstractAiry beam holds great promise for wide applications because of its unique features of being diffraction‐free, self‐accelerating, and self‐healing. Much efforts are devoted to develop concise and efficient methods to generate and manipulate accelerating Airy beams. In this paper, a novel method is proposed to generate single or paired Airy beams by encoding the geometric phase of dielectric metasurface. Cubic phase, together with a linearly gradient phase, is imposed on the metasurface to control the acceleration and initial launching velocity of accelerating Airy beams. Spin‐dependent geometric phase facilitates the generation of spin‐dependent Airy beams by simply controlling the polarization of incident light. High quality of the generated Airy beam is testified by characterization of its diffraction‐free, self‐accelerating, and self‐healing propagation. Despite the loss for silicon in visible region, generation efficiency as high as 63% is achieved for the metasurface Airy beam generator. The results demonstrate the possibility to manipulate complex structured optical field with all‐dielectric metasurface and broaden the potential application of Airy beams into compact and integrated systems.
Solvent selection for extractive distillation using molecular simulation
Authors: Woo Hee Chul , Kim Young Han 
Published: May 2019

AbstractThis study examines a search for a new solvent for extractive distillation using molecular simulation, and the performance of the proposed extractive distillation processes using the solvents is compared to conventional processes. Unlike other solvent search procedures, the proposed solvent finding technique relies on a chemical structure similarity between the solvent and the extracted material without depending on a solvent database. Two new processes of benzene, toluene, and xylenes separation from naphtha reformate and propene/propane separation are compiled with the newly developed solvents for the performance examination. The simulation of the proposed extractive distillation processes demonstrates a significant performance improvement in energy saving and investment cost over conventional processes.
Palladium Catalyzed C−H Olefination of Indolizines at the 1‐Position with Molecular Oxygen as the Terminal Oxidant
Authors: Lu Mingzhu , Shi Fei , Ji Meishan , Kan Yuhe , Hu Huayou 
Published: May 2019

AbstractA regioselective C1‐olefination of indolizines enabled by PdII‐catalyzed non‐directed C−H activation has been developed. Molecular oxygen is employed in this protocol as the terminal oxidant and with a catalytic amount CuII salt as the co‐oxidant. A broad range of simple and highly fused indolizine substrates were compatible with the reaction conditions, enabling the straightforward synthesis of valuable C1‐substituted indolizine derivatives.
Selective Inhibitors of FKBP51 Employ Conformational Selection of Dynamic Invisible States
Authors: Jagtap Pravin Kumar Ankush , Asami Sam , Sippel Claudia , Kaila Ville R. I. , Hausch Felix , Sattler Michael 
Published: May 2019

AbstractThe recently discovered SAFit class of inhibitors against the Hsp90 co‐chaperone FKBP51 show greater than 10 000‐fold selectivity over its closely related paralogue FKBP52. However, the mechanism underlying this selectivity remained unknown. By combining NMR spectroscopy, biophysical and computational methods with mutational analysis, we show that the SAFit molecules bind to a transient pocket in FKBP51. This represents a weakly populated conformation resembling the inhibitor‐bound state of FKBP51, suggesting conformational selection rather than induced fit as the major binding mechanism. The inhibitor‐bound conformation of FKBP51 is stabilized by an allosteric network of residues located away from the inhibitor‐binding site. These residues stabilize the Phe67 side chain in a dynamic outward conformation and are distinct in FKBP52, thus rationalizing the basis for the selectivity of SAFit inhibitors. Our results represent a paradigm for the selective inhibition of transient binding pockets.
Biocatalytic Strategy for Highly Diastereo‐ and Enantioselective Synthesis of 2,3‐Dihydrobenzofuran‐Based Tricyclic Scaffolds
Authors: Vargas David A. , Khade Rahul L. , Zhang Yong , Fasan Rudi 
Published: May 2019

Abstract2,3‐Dihydrobenzofurans are key pharmacophores in many natural and synthetic bioactive molecules. A biocatalytic strategy is reported here for the highly diastereo‐ and enantioselective construction of stereochemically rich 2,3‐dihydrobenzofurans in high enantiopurity (>99.9% de and ee), high yields, and on a preparative scale via benzofuran cyclopropanation with engineered myoglobins. Computational and structure‐reactivity studies provide insights into the mechanism of this reaction, enabling the elaboration of a stereochemical model that can rationalize the high stereoselectivity of the biocatalyst. This information was leveraged to implement a highly stereoselective route to a drug molecule and a tricyclic scaffold featuring five stereogenic centers via a single‐enzyme transformation. This work expands the biocatalytic toolbox for asymmetric C–C bond transformations and should prove useful for further development of metalloprotein catalysts for abiotic carbene transfer reactions.
Target Enzyme‐Activated Two‐Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two‐Dimensional Design Strategy
Authors: Ning Jing , Wang Wei , Ge Guangbo , Chu Peng , Long Feida , Yang Yongliang , Peng Yulin , Feng Lei , Ma Xiaochi , James Tony D. 
Published: May 2019

AbstractThe rapid development of fluorescent probes for monitoring target enzymes is still a great challenge owing to the lack of efficient ways to optimize a specific fluorophore. Herein, a practical two‐dimensional strategy was designed for the development of an isoform‐specific probe for CYP3A4, a key cytochrome P450 isoform responsible for the oxidation of most clinical drugs. In first dimension of the design strategy, a potential two‐photon fluorescent substrate (NN) for CYP3A4 was effectively selected using ensemble‐based virtual screening. In the second dimension, various substituent groups were introduced into NN to optimize the isoform‐selectivity and reactivity. Finally, with ideal selectivity and sensitivity, NEN was successfully applied to the real‐time detection of CYP3A4 in living cells and zebrafish. These findings suggested that our strategy is practical for developing an isoform‐specific probe for a target enzyme.