bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using learning styles in learning objects: a case study in a colombian public university
Authors: Pérez-Gutiérrez Boris 
Published: February 2019

AbstractBackground: computer-programming courses aren’t easy to study. Some authors have studied the difficulties in learning programming to support developing learning materials for basic programming courses. In Colombia there is an approach to teaching programming using an active learning approach (Interactive Learning Objects – ILOs) as one of the components that reinforce their pedagogical model, by supporting the generation of high-level programming skills. Objective: we want to explore the possibilities of using Learning Styles and Team Learning to increase the learning levels of Computer Programming students. Methods: this study was applied outside of the classroom in order to encourage autonomous learning. To do this we’ll pick a sample and apply a series of comparative tests between research groups. Results: the objective was met by effectively showing that providing content based LS and team-based leaning can improve a student’s performance. The intervention group grades were better than those of the comparison group though they should be analyzed further to get a more accurate conclusion. Conclusion: This study will give us the chance to see whether the strategy can be applied to the Francisco de Paula Santander University students.Keywords: Active learning, informal learning, learning objects, learning styles, team-based learning Resumen Antecedentes: la programación de computadores es un tema difícil de aprender. Algunos autores han estudiado las dificultades en el aprendizaje de la programación para soportar el desarrollo de materiales de aprendizaje para los cursos básicos de programación. En Colombia hay un enfoque para enseñar programación usando aprendizaje activo (Objetos Interactivos de Aprendizaje) como uno de los componentes que refuerzan el modelo pedagógico, al apoyar la generación de habilidades de programación de alto nivel. Objetivo: se busca explorar las posibilidades al utilizar Estilos de Aprendizaje y Aprendizaje en Equipo para mejorar en los estudiantes los niveles de aprendizaje de programación. Métodos: este estudio se aplicó fuera del salón de clase para fomentar el aprendizaje autónomo. Para esto se seleccionó una muestra y se aplicaron una serie de pruebas comparativas entre los grupos de investigación. Resultados: el objetivo se cumplió al mostrar que efectivamente que esta estrategia puede mejorar el desempeño de un estudiante. Las calificaciones del grupo de intervención fueron mejores que las del grupo de comparación, sin embargo, estos resultados deben analizarse a profundidad para obtener una conclusión para exacta. Conclusión: este estudio nos dará la oportunidad de revisar si esta estrategia puede aplicarse a los estudiantes de la Universidad Francisco de Paula Santander.Palabras clave: Aprendizaje activo, aprendizaje basado en equipos, aprendizaje informal, estilos de aprendizaje, objetos de aprendizaje.
Multi-Perspective Tolerance Evaluation of Bacillus Calmette-Guerin with Interferon in the Treatment of Non-Muscle Invasive Bladder Cancer
Authors: Steinberg Ryan L. , Thomas Lewis J. , Mott Sarah L. , O’Donnell Michael A. 
Published: February 2019

Background: Bacillus Calmette-Guerin (BCG) toxicities have been reported but with relative agranularity regarding severity and temporal changes during therapy. In its most severe form, BCG intolerance remains poorly understood and exploring ways to optimize toleration of the most effective treatment (BCG) is prudent. Objective: To report the results of both patient- and physician-centered metrics of BCG toxicity as part of the National Phase II BCG/Interferon (IFN) study, as well as the efficacy of low-dose BCG/IFN for previously deemed BCG intolerant patients. Methods: Patients were treated with 6 weekly treatments of BCG (various dosing based on prior BCG exposure) with 50 million units of IFN. BCG intolerance was strictly defined. Maintenance BCG was instituted if disease free. Treatment tolerance during induction was measured using physician- and patient-completed evaluations. Linear mixed effects regression was used to evaluate differences. Results: 533 BCG naïve, 415 BCG failure, and 37 BCG intolerant patients were enrolled. There was no significant difference in quality of life scores between groups ( p = 0.70). A predictable temporal toxicity pattern was identified in all groups with symptom resolution by day 2-3. Despite BCG intolerant patients having significantly worse bladder pain/spasms and cystitis, treatment discontinuation was under 4%. Recurrence-free survival was similar between naïve and intolerant patients. Conclusions: BCG toxicity is common and follows a predictable pattern. While at slightly increased risk of toxicity, BCG intolerant patients may be managed successfully with 1/10th dose BCG with IFN.
Impact of yoga based mind-body intervention on systemic inflammatory markers and co-morbid depression in active Rheumatoid arthritis patients: A randomized controlled trial
Authors: Gautam Surabhi , Tolahunase Madhuri , Kumar Uma , Dada Rima 
Published: February 2019

Background: Recovery of patients with rheumatoid arthritis (RA) depends on several physical and psychological factors, besides pharmacological treatment. Co-morbid depression adversely affects the outcome in RA. Usual medical therapies have a limited scope and fail to cure the psychological component of the disease. With advanced therapeutic options, achieving a state of remission has become the treatment goal, yoga based mind body intervention (MBI) may provide a holistic approach in its treatment dimension. Hence, MBIs are the need of hour as majority of diseases have a psychosomatic component. Objective: To explore the effect of Yoga based MBI on disease specific inflammatory markers and depression severity in active RA patients on routine disease modifying anti-rheumatic drugs (DMARDs) therapy. Methods: A total of 72 RA patients were randomized into 2 groups: yoga group (yoga with DMARDs) and control group (DMARDs only). Blood samples were collected pre and post intervention for primary outcome measurements of systemic biomarkers. Disease activity score 28, erythrocyte sedimentation rate (DAS28ESR) and health assessment questionnaire disability index (HAQ-DI) were used to assess disease activity and functional status respectively at pre and post intervention time-points. Secondary outcome, depression severity, was assessed by Beck Depression Inventory II scale (BDI-II) at 2 weekly intervals during 8 weeks of the study interventional plan. Results: After 8 weeks of yoga based MBI, there was significant decrease in the severity of RA as seen by reduction in levels of various systemic inflammatory markers as well as in DAS28ESR ( p-value <0.0001; effect size = 0.210) and HAQ-DI ( p-value 0.001; effect size = 0.159). Also, yoga group experienced a statistically significant time dependent step-wise decline in depression symptoms over the period of 8 weeks as compared to control group ( p-value <0.0001; effect size = 0.5). Regression analysis showed greater reduction in the scores of BDI-II with DAS28ESR (R2 = 0.426; p <  0.0001) and HAQ-DI (R2 = 0.236; p = 0.003) in yoga group. Conclusions: Yoga, a mind body intervention re-established immunological tolerance by aiding remission at molecular and cellular level along with significant reduction in depression. Thus in this severe autoimmune inflammatory arthritis with a major psychosomatic component, yoga can be used as a complementary/adjunct therapy.
Analisis Pola Migrasi Penduduk di Dataran Tinggi Kabupaten Aceh Tengah Provinsi Aceh (Dimensi Sosial, Ekonomi, dan Infrastruktur)
Authors: Zulhilmi Muhammad , Maulana Hafiizh 
Published: February 2019

Kebijakan pengendalian jumlah penduduk di Kabupaten Aceh Tengah dihadapkan pada persoalan penurunan kualitas penduduk dengan tingginya jumlah imigran yang masuk. Penelitian ini ingin menjawab serangkaian permasalah migrasi dengan menelaah secara mendalam pola migrasi penduduk dan faktor-faktor yang mempengaruhinya. Penelitian dilakukan pada 14 kecamatan di Kabupaten Aceh Tengah, dengan model estimasi migrasi data cross section. Model migrasi yang dihasilkan membagi model dalam lingkup sosial, ekonomi/ketenagakerjaan, dan infrastruktur. Pola migrasi risen yang masuk di Kabupaten Aceh Tengah secara sosial dipengaruhi oleh faktor pendidikan, beban ketergantungan yang tinggi, fasilitas kesehatan. Sementara dalam lingkup ekonomi, tingkat partisipasi angkatan kerja dan jumlah penduduk bekerja menambah tingginya migrasi risen yang masuk.Dalam lingkup infrastruktur penduduk akan bergerak secara masif terjadi karena faktor akses perumahan dan sumber penerangan listrik. Pemerintah Kabupaten Aceh Tengah diharapkan dapat responsif dalam membuat perencanaan pembangunan yang berbasis kependudukan dengan memperhatikan faktor migrasi penduduk di daerah tersebut.
Sinop Yarımadası Kıyıları (Güney Karadeniz, Türkiye) Makroalg Topluluklarının Zamansal Değişimi
Authors: Karaçuha Ali , Yıldız Gökhan , Ersoy Karaçuha Melek 
Published: February 2019

Bu
çalışmada, Karadeniz’in Sinop Yarımadası çevresindeki mevcut denizel makroalg
türlerinin dağılımı ve biyokütlesindeki
mevsimsel değişimler
incelenmiştir. Örneklemeler Eylül 2013-Temmuz 2014 tarihleri arasında 2-5 m
derinlikler arasında yer alan dokuz farklı istasyonda gerçekleştirilmiştir. Alg
örnekleri tüple dalış yapılarak metal bir çerçeve (20x20cm) ile üç tekerrürlü
olarak elle toplanmıştır. Araştırma sonucunda, 6’sı Chlorophyta, 6’sı
Ochrophyta ve 18’i Rhodophyta olmak üzere toplam 30 takson tespit edilmiştir.
İstasyonlar genelinde tespit edilen en baskın türler Cystoseira crinita Duby, 1830 (%53) ve Cystoseira barbata (Stackhouse) C.Agardh, 1820 (%37) olup bunu Polysiphonia fucoides (Hudson) Greville,
1824 ve Ceramium spp. türleri izlediği
tespit edilmiştir. İstasyonlar genelinde
ortalama en yüksek biyokütle değeri 8861.9 gm-2 (yaş ağırlık)ile
Taşocağı istasyonunda, en düşük değer ise Ayı İni Koyu (4006.8 gm-2)
istasyonundan elde edilmiştir. Örnekleme boyunca tespit edilen biyokütle değerinin
2150.6 gm-2 (Karakum
istasyonu, yaz mevsimi) ile 10947.2
gm-2 (Taşocağı istasyon, ilkbahar) arasında değişim gösterdiği
saptanmıştır. Bu çalışma ile Karadeniz’in Sinop Yarımadası kıyılarındaki
makroalg türleri ve biyokütlelerindeki mevsimsel değişikliklere değinerek
dinamikler bilgisine katkıda bulunulmaya çalışılmıştır.
Le soi jeune dedans et dehors
Authors: Ben Salah Laila 
Published: February 2019

Cette présentation se propose de passer en revue, dans une perspective sociolinguistique, les expressions utilisées par les jeunes fassis pour peindre leur propre identité par rapport à l'espace qu'ils occupent dans la finalité de se donner une image distinguée et imposante. Nous allons donc essayer d'examiner les mises en mots de l'identité par les jeunes informateurs qui se façonnent et se définissent par rapport aux autres acteurs sociaux, construisant ainsi des représentations et des visions. Cette recherche résulte d’une enquête de terrain auprès de jeunes informateurs issus de la ville de Fès dont l’âge varie entre seize et vingt-quatre ans. L'enquête a été effectuée au cours des années 2013 et 2014. Il s’agit de cinq heures d’enregistrements réalisés dans différents espaces : à la piscine, au café et au centre commercial de la liberté.
Communication écrite sur Internet et par sms en arabizi : analyse de corpus relevant des glosses dialectales libanaise et marocaine
Authors: Dichy Joseph , Driss Fatima-Zahra , Lagraf Hassiba , Mostefa Djamel 
Published: February 2019

Cette communication, inscrite dans le projet de recherche PARADE (partenaires : SYSTRAN, Laboratoire ICAR et ARADIC Editions), porte sur des analyses de copus en arabizi, qui correspond à l’usage sur Internet, réseaux sociaux ou SMS de l’arabe noté en caractères latins selon des modes de transcriptions issus de l’uage. Après un bref rappel de l’expansion d’Internet dans le monde arbe, de la littérature sur l’arabizi et des transcriptions qu’on y rencontre, les auteur(e)s procèdent à l’analyse de quatre brefs échanges sur Twitter. Deux concernent des internautes marocain(e)s et deux autres, des internautes libanais(es). Protégées par des pseudonymes, ces personnes s’expriment librement, à la fois quant au contenu et quant aux formes linguistiques qu’elles choisissent. Les données sont complexes. On y trouve : (1) des textes en arabizi, transcrivant le dialecte de l’auteur(e) ; (2) des textes en caractères arabes dans l’un des dialectes, l’un des arabes moyens ou en arabe littéraire moderne ; (3) de l’anglais ou du français (voire de l’espagnol ou de l’italien), soit en tant que tels (alternance codique), soit sous forme d’emprunts ; (4) des émoticônes qui sont parfois répétées (itération) ; (5) un usage de caratères de grande dimension, à côté des caractères habituels, ce qui correspond à une fonction expressive ; (6) des images. Les échanges relèvent la plupart du temps d’une analyse interactionnelle, ce qui rend leur interpétation fortement dépendante du contexte. Cette première intervention montre que la question fondamentale – pour un linguiste – est, au-delà de « qu’est-ce l’abizi ? », celle de savoir « comment fonctionne l’arabizi ? »
Consistency of satellite-based precipitation products in space and over time compared with gauge observations and snow- hydrological modelling in the Lake Titicaca region
Authors: Satgé Frédéric , Ruelland Denis , Bonnet Marie-Paule , Molina Jorge , Pillco Ramiro 
Published: February 2019

Abstract. This paper proposes a protocol to assess the space–time consistency of 12
satellite-based precipitation products (SPPs) according to various
indicators, including (i) direct comparison of SPPs with 72 precipitation
gauges; (ii) sensitivity of streamflow modelling to SPPs at the outlet of
four basins; and (iii) the sensitivity of distributed snow models to SPPs
using a MODIS snow product as reference in an unmonitored mountainous area.
The protocol was applied successively to four different time windows
(2000–2004, 2004–2008, 2008–2012 and 2000–2012) to account for the
space–time variability of the SPPs and to a large dataset composed of
12 SPPs (CMORPH–RAW v.1, CMORPH–CRT v.1, CMORPH–BLD v.1, CHIRP v.2, CHIRPS
v.2, GSMaP v.6, MSWEP v.2.1, PERSIANN, PERSIANN–CDR, TMPA–RT v.7, TMPA–Adj
v.7 and SM2Rain–CCI v.2), an unprecedented comparison. The aim of using
different space scales and timescales and indicators was to evaluate whether
the efficiency of SPPs varies with the method of assessment, time window and
location. Results revealed very high discrepancies between SPPs. Compared to
precipitation gauge observations, some SPPs (CMORPH–RAW v.1, CMORPH–CRT
v.1, GSMaP v.6, PERSIANN, and TMPA–RT v.7) are unable to estimate regional
precipitation, whereas the others (CHIRP v.2, CHIRPS v.2, CMORPH–BLD v.1,
MSWEP v.2.1, PERSIANN–CDR, and TMPA–Adj v.7) produce a realistic
representation despite recurrent spatial limitation over regions with
contrasted emissivity, temperature and orography. In 9 out of 10 of the cases
studied, streamflow was more realistically simulated when SPPs were used as
forcing precipitation data rather than precipitation derived from the
available precipitation gauge networks, whereas the SPP's ability to
reproduce the duration of MODIS-based snow cover resulted in poorer
simulations than simulation using available precipitation gauges.
Interestingly, the potential of the SPPs varied significantly when they were
used to reproduce gauge precipitation estimates, streamflow observations or
snow cover duration and depending on the time window considered. SPPs thus
produce space–time errors that cannot be assessed when a single indicator
and/or time window is used, underlining the importance of carefully
considering their space–time consistency before using them for
hydro-climatic studies. Among all the SPPs assessed, MSWEP v.2.1 showed the
highest space–time accuracy and consistency in reproducing gauge
precipitation estimates, streamflow and snow cover duration.
Brexit. Het Verenigd Koninkrijk en de Europese Unie: een moeizaam partnerschap
Authors: de Zwaan J.W. 
Published: February 2019

Brexit. Het Verenigd Koninkrijk en de Europese Unie: een moeizaam partnerschap
In deze bijdrage wordt een overzicht gegeven van de hoofdzaken betreffende het Brexit-dossier. Stilgestaan wordt bij het referendum van 23 juni 2018 en de gang van zaken sinds de kennisgeving van de Britse uittreding op 29 maart 2017. Daarbij komt de stand van zaken in de terugtrekkingsonderhandelingen aan de orde, de Britse voorstellen zoals vervat in het White Paper van juli 2018 en de perspectieven voor oplossingen van de nog uitstaande problemen. Met name de juridisch-institutionele aspecten van de diverse onderwerpen en problemen worden belicht.
Werkzaamheden in meerdere lidstaten voor de Europese socialezekerheidscoördinatie: nadere verduidelijkingen door het Hof van Justitie
Authors: Niesten H. 
Published: February 2019

Werkzaamheden in meerdere lidstaten voor de Europese socialezekerheidscoördinatie: nadere verduidelijkingen door het Hof van Justitie
De geannoteerde twee arresten X/Nederlandse Staatssecretaris van Financiën HvJ 13 september 2017, zaak C-569/15, X/ Staatssecretaris van Financiën, ECLI:EU:C:2017:673 en HvJ 13 september 2017, zaak C-570/15, X/Staatssecretaris van Financiën, ECLI:EU:C:2017:674. van 13 september 2017 illustreren de toenemende diversiteit binnen het grensoverschrijdend werkverkeer. Aan het Hof van Justitie werden prejudiciële vragen gesteld over de betekenis van ‘onbetaald verlof’ en ‘beperkte (thuis)werkzaamheden’ voor de uitleg van de bijzondere regel inzake het verrichten van werkzaamheden in twee of meer lidstaten (dat wil zeggen: samenloop) ter vaststelling van de toepasselijke socialezekerheidswetgeving. Beide arresten nopen tot de vraagstelling of de huidige Europese socialezekerheidscoördinatie voldoende is toegesneden op hedendaagse flexibele arbeidsvormen waar mobilisering en digitalisering de overhand nemen.Verordening (EEG) nr. 1408/71Verordening (EG) nr. 883/2004
Uso didáctico de las TIC en los colegios rurales agrupados de la Región de Murcia
Authors: García María Pilar Segura , Solano Fernández Isabel María , Sánchez Vera María Del Mar 
Published: February 2019

Actualmente, vivimos en una sociedad cada vez más digital, donde las Tecnologías de la Información y la Comunicación (TIC) están provocando un impacto en todos los niveles, también en el educativo. La escuela debe asumir el reto de integrar eficazmente las TIC, promoviendo situaciones enriquecidas con tecnologías en las que la metodología constituya el factor clave de los procesos de innovación educativa. La escuela rural debe hacer frente para ello a las desigualdades existentes, con el firme propósito de superarlas. Desde esta perspectiva, el artículo presenta un estudio descriptivo del uso que en las escuelas rurales de la Región de Murcia se hace de las TIC. La metodología escogida es la mixta, y la recogida de información se ha realizado a través de un cuestionario ad hoc construido para la investigación. Con los resultados obtenidos, hemos podido conocer las necesidades en la disponibilidad de recursos, y el uso didáctico que hacen de las TIC los docentes de los colegios rurales agrupados (CRA) en la Región de Murcia, constatando que aún les cuesta dejar atrás metodologías tradicionales para dar paso a la innovación educativa, a través de tecnologías emergentes.
Today, we live in an increasingly digital society, where Information and Communication Technologies (ICT) are causing an impact at all ranges, in the educative even. The school must take on the challenge of effectively integrating ICT, promoting situations enriched with technologies in which methodology was the key factor in educational innovation processes. Rural schools must take up this challenge, assuming existing inequalities, but with the firm intention of overcoming them. From this perspective, the article presents a descriptive study of the use of ICT in rural schools in the Region of Murcia. The methodology chosen is mixed, and the collection of information has been carried out through an ad hoc questionnaire constructed for research. From the analysis of data, we have been able to know the needs in the availability of resources, and the didactic use that the teachers of the rural schools grouped together in the Region of Murcia make of the ICT, confirming that it is still difficult for them to leave behind traditional methodologies to give way to the educational innovation, through emerging technologies.
Ellipse packing in two-dimensional celltessellation: A theoretical explanation for Lewis’s law and Aboav-Weaire’s law
Authors: Xu Kai 
Published: February 2019

Background: Lewis’s law and Aboav-Weaire’s law are two fundamental laws used to describe the topology of two-dimensional (2D) structures; however, their theoretical bases remain unclear.
Methods: We used R package Conicfit software to fit ellipses based on the geometric parameters of polygonal cells with ten different kinds of natural and artificial 2D structures.
Results: Our results indicated that the cells could be classified as ellipse’s inscribed polygon (EIP) and that they tended to form ellipse’s maximal inscribed polygon (EMIP). This phenomenon was named as ellipse packing. On the basis of the number of cell edges, cell area, and semi-axes of fitted ellipses, we derived and verified new relations of Lewis’s law and Aboav-Weaire’s law .
Conclusions: Ellipse packing is a short-range order that places restrictions on the cell topology and growth pattern. Lewis’s law and Aboav-Weaire’s law mainly reflect the effect of deformation from circle to ellipse on cell area and the edge number of neighboring cells, respectively. The results of this study could be used to simulate the dynamics of cell topology during growth.
MCM2 partial silencing inhibits apical dominance and promotes chlorophyll pigmentation in tomato
Authors: Gao Ma-ye , Liang Jin , Liu Hai-ting , Ni Di-an 
Published: February 2019

Background: We have previously combined loss- and gain-of-function approaches to investigate the function of Arabidopsis minichromosome maintenance (MCM) protein subunit 2 (MCM2). However MCM2 loss of function leads to the death of embryos, thus precluding the analysis of homozygous MCM2 mutants.
Methods: To further understand the function of MCM2, we generated transgenic tomato plants via RNA interference silencing. And microarray slide hybridization was used to compare gene expression level between LeMCM2 -silenced lines and wild-type plants.
Results: We obtained 4 LeMCM2 -silenced lines. The expression level in LeMCM2 -silenced lines was 20-80% of that of wild-type. And LeMCM2 -silenced lines display loss of apical dominance, enhanced chlorophyll accumulation and reduced leaf cell endoduplication. In addition, the expression levels of genes involved in DNA replication was altered in LeMCM2 -silenced lines significantly.
Conclusion: In general, the data described here provided additional evidence for the relationship between genes involved in DNA replication and apical dominance and chlorophyll pigmentation.