bluuebunny/crossref_metadata_2025_split huggingface dataset:
Realizing the values of natural capital for inclusive, sustainable development: Informing China’s new ecological development strategy
Authors: Zheng Hua , Wang Lijuan , Peng Wenjia , Zhang Cuiping , Li Cong , Robinson Brian E. , Wu Xiaochen , Kong Lingqiao , Li Ruonan , Xiao Yi , Xu Weihua , Ouyang Zhiyun , Daily Gretchen C. 
Published: April 2019

Significance
Achieving inclusive, green development is crucial to China and the world. Over the past century, great increases in agricultural production have been achieved at the expense of other ecosystem benefits, such as flood control, water purification, climate stabilization, and biodiversity conservation. We report on an application of China’s new “Ecological Development Strategy,” which aims to break these trade-offs and be scaled nationwide. Focusing on Hainan Island, where rubber production has driven loss of natural forest, we identified a two-pronged strategy that would eliminate these trade-offs, simultaneously diversifying and enhancing product provision, rural incomes, and many other ecosystem benefits. This win−win approach has broad applicability in the plantation regions in China, across South and Southeast Asia, and beyond.
Superhydrophobic frictions
Authors: Mouterde Timothée , Raux Pascal S. , Clanet Christophe , Quéré David 
Published: April 2019

Significance
The matchless mobility of water on superhydrophobic materials is often considered as the hallmark of water repellency. The friction of drops is indeed found to be unusual: instead of observing classical friction such as due to contact line and liquid viscosity, we show that the main source of resistance to the water motion arises from the air around it. This explains why the drop velocity becomes quasi-independent of its viscosity at low viscosity and more generally why the mobility is so high. We also discuss the case of more viscous liquids whose rolling motion induces a bulk viscous dissipation that caps the mobility.
Translingual quoting in journalism
Authors: Haapanen Lauri , Perrin Daniel 
Published: April 2019

Abstract
This chapter focuses on translingual quoting (TQ), i.e. the sub-process of news-writing by which utterances from sources are both quoted and translated. Analyses of journalists’ mental and material activities suggest conceptualizing TQ as a complex and dynamic activity in which journalists’ individual and collective (e.g. institutional) language awareness, knowledge, and practices interact with multi-layered contexts of text production. Based on this empirically and theoretically grounded concept of TQ, the chapter presents a two-part typology of TQ: in sequential TQ, ready-made media items or interview materials are translated into another language; in parallel TQ, interviews and/or texts for media items are produced in different languages by one and the same journalist.
News translation on the Canadian Broadcasting Corporation’s English and French websites
Authors: Gendron Philippe , Conway Kyle , Davier Lucile 
Published: April 2019

Abstract
This chapter examines the techniques journalists use to incorporate translated speech into news stories published on the websites of the French and English networks of the Canadian Broadcasting Corporation. It examines four sets of stories: national political news in French (76 stories) and in English (63 stories) and local news from Canada’s capital region in French (85 stories) and in English (98 stories). It combines content analysis, textual analysis, and ethnography to provide an update of past research about the Corporation’s television news programs in the early 1990s. It reveals that the asymmetries that have long shaped the Corporation’s French- and English-language news continue to operate, although in different form, and they continue to influence the ways journalists incorporate translated speech into their stories.
Technological convergence threatening translation
Authors: Davier Lucile 
Published: April 2019

Abstract

Le Droit is a monolingual French-language regional newspaper targeting audiences in two Canadian provinces. Although its multimodal content appears to be in French only, English permeates the daily work of reporters. Data include sessions of observation, semi-structured interviews, and text collection on different platforms (print, website, applications, and social media). This chapter shows that, at the level of news-gathering, contacts with English sources seem partially unavoidable or even desirable. At the level of production, however, all traces of translation are erased in the written form, while French voices are systematically preferred in audiovisual content. The growing importance of audiovisual content seems to predict the exclusion of sources in a second language.
/h/ insertion as a ‘camouflage archaism’?
Authors: Schreier Daniel 
Published: April 2019

AbstractThis article documents the historical development and synchronic variation of so-called “/h/ insertion” (/h/ before vowel-initial words such asapple,under, etc.). It argues that the maintenance of /h/ insertion in post-colonial English varieties around the world provides an ideal opportunity for research on language change under dialect contact scenarios involving British donors and other dialects. After an assessment of regional distribution patterns in current World Englishes, I present some first findings from a large-scale quantitative analysis of Tristan da Cunha English, where /h/ insertion, firmly attested yet nearing obsolescence in British English, has survived into the 21st century. The quantitative analysis provides important insights into donor attribution and competition-selection processes that accompany dialect contact and koinéization, with special reference to theoretical concepts such as colonial lag, feature pool formation and founder effects. A holistic application of the concept of colonial lag to post-colonial English varieties needs to be refined and critically assessed. I argue that entire linguistic systems (in the form of koinés) are not conservative as such but that arrested language (and dialect) change operates on a feature-specific level instead.
Elements of syntax
Authors: van Riemsdijk Henk 
Published: April 2019

Abstract
This contribution presents a somewhat autobiographical overview of the author’s struggle in coming to grips with the undeniable central role that the forces of attraction and repulsion play in the grammar of natural languages. It is therefore a tale of good and bad ideas, where the bad ideas sometimes suppressed the good ones. After disentangling these previous attempts at a more or less comprehensive theory of repulsion and attraction, I present a sketchy research program for where I think we need to go to find a satisfactory solution.
Preliminaries to delicate matters
Authors: Lim Ni-Eng 
Published: April 2019

Abstract
The meta-language unit “I say to you” is frequently heard in Mandarin Chinese conversations, and are most commonly expressed as wo gen ni shuo ‘I say to you’, wo gen ni jiang ‘I talk to you’, or wo gaosu ni ‘I tell you’, collectively termed “I-say-to-you” expressions. Quantitative investigations reveal that they are dedicated interactional resources found only in spoken conversation. By using conversation analytic methodology, further examination of their sequential trajectory shows that a core function of “I-say-to-you” expressions is to preface upcoming “delicate” matters, such as dispreferred next action, disagreement or disaffiliative turn, and other actions that may be resistance-implicative for the recipient. As a preface, “I-say-to-you” expressions can be used by the speaker to secure multi-turns space with which to gradually deliver the “delicate” matter and achieve other interactional goals.
MiR-125b regulates the proliferation and metastasis of triple negative breast cancer cells via the Wnt/β-catenin pathway and EMT
Authors: Nie Jun , Jiang Hong-Chao , Zhou Yong-Chun , Jiang Bo , He Wen-Jie , Wang Yu-Feng , Dong Jian 
Published: April 2019

ABSTRACT
Background/aim: MiR-125b plays an important role in breast cancer. The current study was to explore the expression and function of miR-125b in triple negative breast cancer cells. Materials and methods: The expression of miR-125b in human TNBC samples and cell lines were examined by qRT-PCR. MTT, scratch assays and transwell assays were utilized to observe the proliferation, migration and invasion ability. MiR-125b’s target gene and downstream signaling pathways were investigated by Luciferase Reporter Assays, qRT-PCR, immunofluorescence assays and western bolt. Results: MiR-125b was highly expressed in human TNBC tissues and cell lines. Inhibiting miR-125b expression suppressed the proliferation, cell migration and invasion. The three-prime untranslated region (3´-UTR) of adenomatous polyposis coli (APC) mRNA contains miR-125b binding sites, and inhibiting miR-125b expression suppressed the activity of the intracellular Wnt/β-catenin pathways and EMT. Conclusion: Inhibiting miR-125b regulates the Wnt/β-catenin pathway and EMT to suppress the proliferation and migration of MDA-MB-468 TNBC cells.
Learner agency and the curriculum: a critical realist perspective
Authors: Manyukhina Yana , Wyse Dominic 
Published: April 2019

AbstractAgency, understood as the capacity to act independently and to make one's own choices, is considered central to children's development. Thus, education, and hence education curricula, have a role in the development of learner agency. While curriculum development is a key focus for educational theory, research, policy, and classroom practice, the potential implications of curriculum content selections for learner agency remain underexplored. Theoretically, this paper engages with critical realism, explaining how it can provide theoretical foundation for a more comprehensive view of learner agency and, by implication, more balanced curricula. Empirically, the paper draws on the findings from a content analysis of the national curriculum documents of four countries with relatively high scores in international comparative tables, England, Australia, Hong‐Kong, and Canada, to develop a new typology of primary curricula. Based on the extent of emphasis placed on knowledge versus skills, values, and attitudes, three types of curricula were identified: knowledge‐based, skills‐oriented, and learner‐centred. Due to its significant theoretical and practical influence globally, we focus on the knowledge‐based model and its likely impact on students’ agency. We conclude by highlighting the importance of making learner agency a key orientation of the curriculum and suggesting directions for future research.
PARTY POLITICS IN PORTUGAL
Authors: Antónia Pires de Almeida Maria 
Published: April 2019

ABSTRACT
Since the Portuguese revolution of April 25th, 1974, and the beginning of the democratic regime (with the first elections for parliament held on April 25th, 1975), political parties dominate the electoral process, both on central government and on the municipalities. The analysis of the political elites, their party filiations and recruitment and their social backgrounds has occupied Portuguese social scientists for the last years. With this paper, the author proposes to establish the relationship between these two levels of government, national and local, and access the importance of political parties in each of them. Many mayors’ political careers include vertical mobility, both upwards and downwards: from mayors to members of parliament to members of the European Parliament and ministers or even Prime Minister and President of the Republic (in the case of two mayors of Lisbon), or from ministers and members of parliament to mayors. In all of these cases, their party and their position within the party has played a central role, even when some individuals have pursued other party choices in order to get re-elected, or even have presented independent candidacies (only possible since 1997).
HiCNN: a very deep convolutional neural network to better enhance the resolution of Hi-C data
Authors: Liu Tong , Wang Zheng 
Published: April 2019

Abstract

Motivation
High-resolution Hi-C data are indispensable for the studies of three-dimensional (3D) genome organization at kilobase level. However, generating high-resolution Hi-C data (e.g. 5 kb) by conducting Hi-C experiments needs millions of mammalian cells, which may eventually generate billions of paired-end reads with a high sequencing cost. Therefore, it will be important and helpful if we can enhance the resolutions of Hi-C data by computational methods.

Results
We developed a new computational method named HiCNN that used a 54-layer very deep convolutional neural network to enhance the resolutions of Hi-C data. The network contains both global and local residual learning with multiple speedup techniques included resulting in fast convergence. We used mean squared errors and Pearson’s correlation coefficients between real high-resolution and computationally predicted high-resolution Hi-C data to evaluate the method. The evaluation results show that HiCNN consistently outperforms HiCPlus, the only existing tool in the literature, when training and testing data are extracted from the same cell type (i.e. GM12878) and from two different cell types in the same or different species (i.e. GM12878 as training with K562 as testing, and GM12878 as training with CH12-LX as testing). We further found that the HiCNN-enhanced high-resolution Hi-C data are more consistent with real experimental high-resolution Hi-C data than HiCPlus-enhanced data in terms of indicating statistically significant interactions. Moreover, HiCNN can efficiently enhance low-resolution Hi-C data, which eventually helps recover two chromatin loops that were confirmed by 3D-FISH.

Availability and implementation
HiCNN is freely available at http://dna.cs.miami.edu/HiCNN/.

Supplementary information
Supplementary data are available at Bioinformatics online.
β-hCG-induced mutant BRCA1 ignites drug resistance in susceptible breast tissue
Authors: Sengodan Satheesh Kumar , Hemalatha Sreelatha K , Nadhan Revathy , Somanathan Thara , Mathew Arun Peter , Chil Arkadiusz , Kopczynski Janusz , Nair Rakesh Sathish , Kumar Jerald Mahesh , Srinivas Priya 
Published: April 2019

Abstract
β-hCG expression in breast cancer is highly controversial with reports supporting both protective and tumorigenic effects. It has also been reported that risk of breast cancer at an early age is increased with full-term pregnancies if a woman is a BRCA1 mutation carrier. We have already demonstrated that BRCA1-defective cells express high levels of β-hCG and that when BRCA1 is restored, β-hCG level is reduced. Also, BRCA1 can bind to the promoter and reduce the levels of β-hCG. β-hCG induces tumorigenicity in BRCA1-defective cells by directly binding to TGFBRII and induces TGFBRII-mediated cell proliferation. In this study, we analyzed the mechanism of action of β-hCG on BRCA1 expression and its influence on drug sensitivity in breast cancer cells. We demonstrate that β-hCG induces mutant BRCA1 protein expression in BRCA1 mutant cells; however, in BRCA1 wild-type cells, β-hCG reduced wild-type BRCA1 protein expression. Transcriptionally, β-hCG could induce Slug/LSD1-mediated repression of wild-type and mutant BRCA1 messenger RNA levels. However, β-hCG induces HSP90-mediated stabilization of mutant BRCA1 and hence the overexpression of mutant BRCA1 protein, resulting in partial restoration of homologous recombination repair of damaged DNA. This contributes to drug resistance to HSP90 inhibitor 17AAG in BRCA1-defective cancer cells. A combination of HSP90 inhibitor and TGFBRII inhibitor has shown to sensitize β-hCG expressing BRCA1-defective breast cancers to cell death. Targeting the β-hCG–HSP90–TGFBRII axis could prove an effective treatment strategy for BRCA1-mutated breast tumors.
Clinical and angiographic outcomes of bioabsorbable vs. permanent polymer drug-eluting stents in Sweden: a report from the Swedish Coronary and Angioplasty Registry (SCAAR)
Authors: Buccheri Sergio , James Stefan , Lindholm Daniel , Fröbert Ole , Olivecrona Göran K , Persson Jonas , Hambraeus Kristina , Witt Nils , Erlinge David , Angerås Oskar , Lagerqvist Bo , Sarno Giovanna 
Published: April 2019

Abstract

Aims
Randomized clinical trials have consistently demonstrated the non-inferiority of bioabsorbable polymer drug-eluting stents (BP-DES) with respect to DES having permanent polymers (PP-DES). To date, the comparative performance of BP- and PP-DES in the real world has not been extensively investigated.

Methods and results
From October 2011 to June 2016, we analysed the outcomes associated with newer generation DES use in Sweden. After stratification according to the type of DES received at the index procedure, a total of 16 504 and 79 106 stents were included in the BP- and PP-DES groups, respectively. The Kaplan–Meier estimates for restenosis at 2 years were 1.2% and 1.4% in BP- and PP-DES groups, respectively. Definite stent thrombosis (ST) was low in both groups (0.5% and 0.7% in BP- and PP-DES groups, respectively). The adjusted hazard ratio (HR) for either restenosis or definite ST did not differ between BP- and PP-DES [adjusted HR 0.95, 95% confidence interval (CI) 0.74–1.21; P = 0.670 and adjusted HR 0.79, 95% CI 0.57–1.09; P = 0.151, respectively]. Similarly, there were no differences in the adjusted risk of all-cause death and myocardial infarction (MI) between the two groups (adjusted HR for all-cause death 1.01, 95% CI 0.82–1.25; P = 0.918 and adjusted HR for MI 1.05, 95% CI 0.93–1.19; P = 0.404).

Conclusion
In a large, nationwide, and unselected cohort of patients, percutaneous coronary intervention with BP-DES implantation was not associated with an incremental clinical benefit over PP-DES use at 2 years follow-up.
Islands in the stream: from individual to communal fiber degradation in the rumen ecosystem
Authors: Moraïs Sarah , Mizrahi Itzhak 
Published: April 2019

ABSTRACT
The herbivore rumen ecosystem constitutes an extremely efficient degradation machinery for the intricate chemical structure of fiber biomass, thus, enabling the hosting animal to digest its feed. The challenging task of deconstructing and metabolizing fiber is performed by microorganisms inhabiting the rumen. Since most of the ingested feed is comprised of plant fiber, these fiber-degrading microorganisms are of cardinal importance to the ecology of the rumen microbial community and to the hosting animal, and have a great impact on our environment and food sustainability. We summarize herein the enzymological fundamentals of fiber degradation, how the genes encoding these enzymes are spread across fiber-degrading microbes, and these microbes' interactions with other members of the rumen microbial community and potential effect on community structure. An understanding of these concepts has applied value for agriculture and our environment, and will also contribute to a better understanding of microbial ecology and evolution in anaerobic ecosystems.
Revisiting gametocyte biology in malaria parasites
Authors: Ngotho Priscilla , Soares Alexandra Blancke , Hentzschel Franziska , Achcar Fiona , Bertuccini Lucia , Marti Matthias 
Published: April 2019

ABSTRACT
Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology. Recent reductions in the global malaria burden have brought the possibility of elimination and eradication, with renewed focus on malaria transmission biology as a basis for interventions. This review discusses recent insights into gametocyte biology in the major human malaria parasite, Plasmodium falciparum and related species.
Trauma, Memory and the Act of Writing in Ruth Klüger’s Autobiographical Project
Authors: Painitz Sarah 
Published: April 2019

Abstract
This essay intends to shed light on the motivation behind Ruth Klüger’s autobiographical project by examining the relationship between trauma, memory and the act of writing. Exploring the catalyst for writing reveals that Klüger’s autobiographical texts have a dual function: they serve as a public call for dialogue, as well as a kind of therapy allowing her to work through the traumas of her past. I demonstrate that for this reason, it is crucial to take into consideration not just the well-known weiter leben: Eine Jugend (1992), but also its revised English self-translation Still Alive: A Holocaust Girlhood Remembered (2001). Writing, editing, revising and translating create a space for Klüger’s continuous engagement with her past and its traumas – an engagement that is ongoing, continuing beyond the first writing of the text, and that stems from an innate desire to understand better the driving forces of her own life and her survival against all odds.
Non-convex low-rank matrix recovery with arbitrary outliers via median-truncated gradient descent
Authors: Li Yuanxin , Chi Yuejie , Zhang Huishuai , Liang Yingbin 
Published: April 2019

AbstractRecent work has demonstrated the effectiveness of gradient descent for directly recovering the factors of low-rank matrices from random linear measurements in a globally convergent manner when initialized properly. However, the performance of existing algorithms is highly sensitive in the presence of outliers that may take arbitrary values. In this paper, we propose a truncated gradient descent algorithm to improve the robustness against outliers, where the truncation is performed to rule out the contributions of samples that deviate significantly from the sample median of measurement residuals adaptively in each iteration. We demonstrate that, when initialized in a basin of attraction close to the ground truth, the proposed algorithm converges to the ground truth at a linear rate for the Gaussian measurement model with a near-optimal number of measurements, even when a constant fraction of the measurements are arbitrarily corrupted. In addition, we propose a new truncated spectral method that ensures an initialization in the basin of attraction at slightly higher requirements. We finally provide numerical experiments to validate the superior performance of the proposed approach.
Association of the quality of antenatal care with neonatal mortality: meta-analysis of individual participant data from 60 low- and middle-income countries
Authors: Neupane Subas , Doku David Teye 
Published: April 2019

AbstractBackgroundWe investigated the quality of antenatal care (ANC) and its effect on neonatal mortality in 60 low- and middle-income countries (LMICs).MethodsWe used pooled comparable cross-sectional surveys from 60 LMICs (n=651 681). Cox proportional hazards multivariable regression models and meta-regression analysis were used to assess the effect of the quality of ANC on the risk of neonatal mortality. Kaplan–Meier survival curves were used to describe the time-to-event patterns of neonatal survival in each region.ResultsPooled estimates from meta-analysis showed a 34% lower risk of neonatal mortality for children of women who were attended to at ANC by skilled personnel. Sufficient ANC advice lowered the risk of neonatal mortality by 20%. Similarly, children of women who had adequate ANC had a 39% lower risk of neonatal mortality. The pooled multivariable model showed an association of neonatal mortality with the ANC quality index (HR 0.85, 95% CI 0.77 to 0.93).ConclusionsImprovement in the quality of ANC can reduce the risk of neonatal mortality substantially. Pursuing sustainable development goal 3, which aims to reduce neonatal mortality to 12 per 1000 live births by 2030, should improve the quality of ANC women receive in LMICs.