bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations Between Anti-Mullerian Hormone and Cardiometabolic Health in Reproductive Age Women Are Explained by Body Mass Index
Authors: Rios Julie S , Greenwood Eleni A , Pavone Mary Ellen G , Cedars Marcelle I , Legro Richard S , Diamond Michael P , Santoro Nanette , Sun Fangbai , Robinson Randal D , Christman Gregory , Zhang Heping , Huddleston Heather G 
Published: October 2019

Abstract

Context
The relationship between reproductive and cardiometabolic aging is unclear. It is unknown if the relationship differs across different clinical populations.

Objective
To determine whether markers of ovarian reserve are associated with cardiometabolic risk in reproductive aged women with unexplained infertility (UI), polycystic ovary syndrome (PCOS), and regularly cycling women (OVA).

Design and setting
Cross-sectional data from 8 US-based academic centers.

Participants
Women aged 25–40 from 3 clinical populations: 870 with UI, 640 with PCOS, and 921 community-based OVA.

Main Outcome Measures
Multivariable linear regression models were used to relate anti-mullerian hormone (AMH) and antral follicle count with cardiometabolic parameters including body mass index (BMI), waist circumference (WC), fasting glucose and insulin, homeostasis model assessment-insulin resistance (HOMA-IR), lipids, and C-reactive protein.

Results
In age and study site-adjusted models, AMH inversely related to BMI in the UI and OVA groups (P = 0.02 and P &lt; 0.001). Among women with PCOS, AMH inversely related to BMI (P &lt; 0.001), and also to WC (P &lt; 0.001), fasting insulin (P &lt; 0.01), HOMA-IR (P &lt; 0.01), triglycerides (P = 0.04), and C-reactive protein (P &lt; 0.001) and directly related to higher total (P = 0.02), low-density lipoprotein (P &lt; 0.01), and high-density lipoprotein cholesterol (P &lt; 0.01). In OVA, AMH also varied inversely with WC (P &lt; 0.001), fasting insulin (P = 0.02), and HOMA-IR (P = 0.02). Adjustment for BMI eliminated associations in the OVA group but in PCOS, the relationship of AMH to total (P = 0.03) and low-density lipoprotein cholesterol (P = 0.003) remained.

Conclusion
Associations observed between AMH and cardiometabolic indices are largely explained by BMI in women with and without PCOS. (J Clin Endocrinol Metab XX: 0-0, 2019)
Impulse Control Disorders in Dopamine Agonist-Treated Hyperprolactinemia: Prevalence and Risk Factors
Authors: De Sousa Sunita M C , Baranoff John , Rushworth R Louise , Butler Jessica , Sorbello Jane , Vorster Juanita , Thompson Tanya , McCormack Ann I , Inder Warrick J , Torpy David J 
Published: October 2019

Abstract

Context
There are growing reports of dopamine agonist (DA)-induced impulse control disorders (ICDs) in hyperprolactinemic patients. However, the magnitude of this risk and predictive factors remain uncertain.

Objective
To determine ICD prevalence and risk factors in DA-treated hyperprolactinemic patients compared to community controls.

Design, Setting and Participants
Multicenter cross-sectional analysis of 113 patients and 99 healthy controls.

Main Outcome Measures
Participants completed a neuropsychological questionnaire consisting of the Depression Anxiety Stress Scale (DASS21), Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease (QUIP-S), Hypersexual Behavior Inventory (HBI), Hypersexual Behavior Consequences Scale and Social Desirability Response Set Scale. Demographic and clinical data were collated to determine ICD risk factors. Patients testing positive for an ICD were offered a semistructured psychological interview.

Results
Patients were more likely than controls to test positive by QUIP-S for any ICD (61.1 vs 42.4%, P = .01), hypersexuality (22.1 vs 8.1%, P = .009), compulsive buying (15.9 vs 6.1%, P = .041) and punding (18.6 vs 6.1%, P = 0.012), and by HBI for hypersexuality (8.0 vs 0.0%, P = 0.004). Independent risk factors were male sex (odds ratio [OR] 13.85), eugonadism (OR 7.85), Hardy’s tumor score and psychiatric comorbidity (OR 6.86) for hypersexuality, and age (OR 0.95) for compulsive buying. DASS21 subset scores were higher in patients vs controls and in patients with vs without different ICDs. Only 19/51 (37.3%) interviewed patients were aware of the relationship between DAs and ICDs before the study.

Conclusions
DA therapy poses a high, previously underestimated risk of ICDs, especially in the form of hypersexuality in eugonadal men.
Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation
Authors: McKeever Liam , Peterson Sarah J , Lateef Omar , Freels Sally , Fonseca Tatiana L , Bocco Barbara M L C , Fernandes Gustavo W , Roehl Kelly , Nowak Kristen , Mozer Marisa , Bianco Antonio C , Braunschweig Carol A 
Published: October 2019

Abstract

Introduction
The inflammatory response of critical illness is accompanied by nonthyroidal illness syndrome (NTIS). Feeding has been shown to attenuate this process, but this has not been explored prospectively over time in critically ill patients.

Objective
To explore the impact of calorie exposure on NTIS over time in critically ill patients.

Methods
Mechanically ventilated patients with systemic inflammatory response syndrome (SIRS) were randomized to receive either 100% or 40% of their estimated caloric needs (ECN). Thyroid hormones were measured daily for 7 days or until intensive care unit discharge or death. Mixed level regression modeling was used to explore the effect of randomization group on plasma triiodothyronine (T3), reverse triiodothyronine (rT3), thyroxine (T4), and thyroid stimulating hormone (TSH), as well as the T3/rT3 ratio.

Results
Thirty-five participants (n=19 in 100% ECN; n=16 in 40% ECN) were recruited. Adjusting for group differences in baseline T3/rT3 ratio, the parameters defining the fitted curves (intercept, linear effect of study day, and quadratic effect of study day) differed by randomization group (P = 0.001, P = 0.01, and P = 0.02 respectively). Plots of the fitted curves revealed that participants in the 100% ECN group had a 54% higher T3/rT3 ratio on postintervention day 1 compared with the 40% ECN group, a difference which attenuated over time. This was driven by a 23% higher plasma T3 and 10% lower plasma rT3 levels on postintervention 1.

Conclusions
Higher caloric exposure in NTIS patients transiently attenuates the drop of the plasma T3/rT3 ratio, an effect that is minimized and finally lost over the following 3 days of continued higher caloric exposure.
The Loss of ARNT/HIF1β in Male Pancreatic β-Cells Is Protective Against High-Fat Diet–Induced Diabetes
Authors: Hoang Monica , Paglialunga Sabina , Bombardier Eric , Tupling A Russell , Joseph Jamie W 
Published: October 2019

Abstract
The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT)/hypoxia-inducible factor (HIF)-1β (ARNT/HIF1β) plays a key role in maintaining β-cell function and has been shown to be one of the most downregulated transcription factors in islets from patients with type 2 diabetes. We have shown a role for ARNT/HIF1β in glucose sensing and insulin secretion in vitro and no defects in in vivo glucose homeostasis. To gain a better understanding of the role of ARNT/HIF1β in the development of diabetes, we placed control (+/+/Cre) and β-cell–specific ARNT/HIF1β knockout (fl/fl/Cre) mice on a high-fat diet (HFD). Unlike the control (+/+/Cre) mice, HFD-fed fl/fl/Cre mice had no impairment in in vivo glucose tolerance. The lack of impairment in HFD-fed fl/fl/Cre mice was partly due to an improved islet glucose-stimulated NADPH/NADP+ ratio and glucose-stimulated insulin secretion. The effects of the HFD-rescued insulin secretion in fl/fl/Cre islets could be reproduced by treating low-fat diet (LFD)–fed fl/fl/Cre islets with the lipid signaling molecule 1-monoacylglcyerol. This suggests that the defects seen in LFD-fed fl/fl/Cre islet insulin secretion involve lipid signaling molecules. Overall, mice lacking ARNT/HIF1β in β-cells have altered lipid signaling in vivo and are resistant to an HFD’s ability to induce diabetes.
Impact of bowel preparation on caecal intubation time during colonoscopy
Authors: Alvi Haris , Rasheed Tazeen , Shaikh Majid Ahmed , Ali Faiza Sadaqat , Zuberi Bader Faiyaz , Samejo Asad Ali 
Published: October 2019

Objective: To determine the caecal intubation time depending on bowel preparation as per Boston Bowel Preparation Scale.
Methods: This cross-sectional study was conducted at Dr. Ruth K. M. Pfau, Civil Hospital Karachi between August 2018 to February 2019. A total of 201 patients were included in the study. Time was recorded from insertion of colonoscope to the time required to reach the cecum. Bowel preparation was graded during withdrawal of colonoscope by using Boston Bowel Preparation Scale. Pearson Correlation test was used to study correlation of BBPS scores with CIT, gender, BMI, adenoma and polyp detection.
Results: In this study 201 patients undergoing colonoscopy were included. Mean ±SD of age of patients was 36.9 ±15.8 years. Out of the 201 patients 112 (56%) were males and 89 (44%) were females. The results of our study showed that increased Boston Bowel Preparation Scale Scores were associated with decreased caecal intubation time. The mean CIT was 10.7 ±5.4 minutes and Pearson correlation was significant at 0.002. Significant correlations of BBPS were also found with BMI and adenoma detection.
Conclusion: The diagnostic effectiveness of colonoscopy depends upon the quality of the preparation. Good bowel preparation improves the speed of colonoscopy and its completeness.
doi: https://doi.org/10.12669/pjms.35.6.1031
How to cite this:Alvi H, Rasheed T, Shaikh MA, Ali FS, Zuberi BF, Samejo AA. Impact of bowel preparation on caecal intubation time during colonoscopy. Pak J Med Sci. 2019;35(6):1516-1519. doi: https://doi.org/10.12669/pjms.35.6.1031
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Blood transfusion and high-order cesarean delivery; Report from a developing country
Authors: Abbas Shahida , Mughal Saba , Hussain Syeda Namayah Fatima , Hossain Nazli 
Published: October 2019

Background and Objective: Blood loss in cesarean deliveries has already been established in previous researches but a detailed insight into the correlates has not been done. This study examined whether the number of previous Cesarean sections is related to the need for blood transfusion, and risk factors for blood transfusion.
Methods: A retrospective review of 239 females who had undergone two or more Cesarean sections during the time period of 2015-2018 was done. Data collected included type of surgery (elective or emergency), age, parity, body mass index, estimated blood loss, operating time, level of surgeon, presence or absence of adhesions and number of transfused packed cell volume.
Results: About 9.2% patients received blood transfusion with an estimated average blood loss of 618.18 ml. Patients with adhesions from previous surgery, presence of placenta previa, multiparity were significantly likely to receive blood transfusion. It was found that women with more than two caesarian sections had high proportion of blood transfusion as compared to women who had two caesarian sections. However non-significant difference was observed in numbers of caesarean sections with blood transfusion.
Conclusion: Women undergoing Cesarean sections combined with any of the risk factors like increased body mass index, dense adhesions, uterine atony, hypertension and presence of placenta previa, were found to be at increased risk for a need for blood transfusions.
doi: https://doi.org/10.12669/pjms.35.6.539
How to cite this:Abbas S, Mughal S, Hussain SNF, Hossain N. Blood transfusion and high-order cesarean delivery; Report from a developing country. Pak J Med Sci. 2019;35(6):1520-1525. doi: https://doi.org/10.12669/pjms.35.6.539
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Book Reviews
Authors: Quinn Kevin , Dines Mike , Bestley Russ 
Published: October 2019

A Hidden Landscape once a Week: The Unruly Curiosity of the UK Music Press in the 1960s–80s, in the Words of Those Who Were There, Mark Sinker (2018) London: Strange Attractor, 392 pp., ISBN 978-1-90722-263-4, p/bk, £15.99
Soap the Stamps, Jump the Tube: A Story of Punk, Motorbikes, Witchcraft, Sandwiches, Squats and Sewing, Gail Thibert (2018) London: Unbound, 272 pp., ISBN 978-1-91261-818-7, p/bk, £10.99
Dayglo! The Poly Styrene Story, Celeste Bell and Zoë Howe (2019) London: Omnibus Press, 192 pp., ISBN 978-1-78558-616-3, h/bk, £25.00
Analisis Penawaran Tenaga Kerja Wanita Memiliki Balita di
Perdesaan Sumatera Barat
Authors: Maryati Sri 
Published: October 2019

Penelitian ini bertujuan untuk menemukan faktor yang mempengaruhi penawaran tenaga
kerja wanita yang memiliki Balita di Sumatera Barat. Keputusan memasuki pasar kerja yang
harus diambil oleh wanita pada umumnya dan wanita yang memiliki balita khususnya sangatlah
kompleks, diantaranya tergantung pada latar belakang individu dan pengaruh keluarga serta
lingkungan. Variabel yang dikaji dalam studi ini adalah karakteristik individu, karakteristik
keluarga dan karakteristik pekerjaan suami, dengan objek penelitian wanita usia produktif (15-64
tahun) yang memiliki Balita di Sumatera Barat, dan daerah penelitian adalah Kabupaten Agam
dan Kabupaten Pasaman. Data yang digunakan adalah data primer dengan metode sensus, alat
pengumpulan data dengan wawancara terstruktur menggunakan daftar pertanyaan (kuesioner).
Metode analisa data dilakukan secara deskriptif dan induktif dengan peralatan analisis statistika
dan ekonometrika. Hasil studi memperlihatkan bahwa penawaran tenaga kerja wanita yang
memiliki balita dipengaruhi oleh variabelumur , tingkat pendidikan , jumlah ART, status RT, dan
kedudukan pekerjaan suami. Dari studi ini juga ditemukan wanita memiliki balita cenderung
memasuki lapangan kerja setelah anaknya cukup aman untuk ditinggalkan atau dibawa bekerja,
penawaran tenaga kerja wanita berbalita bersifat komplementer terhadap pekerjaan suami.
Perfil Dos Gestores Financeiros De Pequenas Empresas Comerciais
Authors: Wernke Rodney , Junges Ivone , Ritta Cleyton de Oliveira , Souza Denize Calegari de 
Published: October 2019

Objetivo: Identificar o perfil dos gestores financeiros de pequenas empresas comerciais sul-catarinenses quanto às funções e papéis que exercem.Método: Pesquisa quantitativa, descritiva e de levantamento de dados (survey)Originalidade/Relevância: O que faz o dirigente da pequena empresa comercial, como gerente financeiro é ainda pouco investigado empiricamente. Esse contexto ressalta a importância de conhecer os estilos gerenciais desses gestores, bem como a necessidade de pesquisar as funções e os papéis do administrador conjuntamente, em vez de estudá-los isoladamente, como ocorre com a maioria das pesquisas.Resultados: Constatou-se que a preocupação maior dos gestores financeiros das empresas pesquisadas é com a função de planejamento, seguida pelas funções de controle, de organização e de alocação de recursos. Quanto aos papéis exercidos predominaram os de monitor, empreendedor, contato, disseminador, liderança e líder.Contribuições teóricas/metodológicas: A aplicação de teste estatístico não-paramétrico indicou que os fatores contingenciais “idade”, “tempo de atuação” e “nível de escolaridade” não influenciam os níveis de prioridade dados pelos gestores financeiros aos papéis e funções.
The Populist and Nationalist Roots of Trump’s Rhetoric
Authors: Rowland Robert C. 
Published: October 2019

Abstract
Donald Trump’s campaign violated every rule of presidential campaigns, and few commentators thought that he had a chance to win the presidency. His success can be traced to the strong affective connection that he created with core supporters. Trump used a rhetoric of nationalist populism with a charismatic outsider persona, a rhetorical pattern that functioned as an affective genre, to create this connection. This pattern is evident in campaign rallies, his speech at the Republican National Convention, and his inaugural address. Trump’s successful use of a rhetoric of nationalist populism has important implications for the status of American democracy.
Blade design for horizontal axis wind turbine: 3D model.
Authors: Albadan Molano David Esteban , Salamanca Céspedes Jorge Enrique 
Published: October 2019

Wind energy is one of the best important sources of renewable energy and an excellent alternative for the transition to sustainable energy that the planet earth needs. The wind energy is contained in the air particles in movement, forming kinetic energy. This energy could be transformed into another type of energy such as electricity, through the use of wind turbines. It is known that horizontal axis wind turbines are more efficient energetically, the power output of a horizontal axis wind turbine depends of it aerodynamic performance; therefore, the correct geometric design of the propeller is essential for an optimum wind turbine. This article analyzes the most relevant aspects in the design of a wind propeller, using MATLAB® software to illustrate its behavior, suggests an ideal airfoil for wind applications to use in the 3D modeling of the blades using the computer assisted design, this blades has been built with a 3D printer.
La universidad del siglo XXI y la idea de tecnología, educación y comunicación
Authors: Castaño Támara Ricardo , Gordo Muskus Ricardo 
Published: October 2019

El presente artículo presenta reflexiones teóricas en torno a la discusión del papel de la tecnología y la comunicación que se ha establecido en la Universidad del siglo XXI. En primer lugar se aborda el problema de la educación y la tecnología debido al alto grado y la rapidez con la que esta última se desarrolla y renueva en nuestros días, de ahí que deba asumirse, desde la educación, el reto de orientar críticamente el significado de tales avances. El documento concluye con el análisis de qué papel se le endilga a la comunicación en la construcción de los conceptos de educación, tecnología y desarrollo al interior de la universidad, presentando desde la discusión académica algunas perspectivas y salidas que se consideran significativas para reconfigurar estos conceptos en pro de un estamento estudiantil más crítico a las ideas que desde las aulas de clase se intentan establecer para la configuración de una ciudadanía global.
The The Impact of Organization culture and Work Environment on Employee Engagement and It’s Implication on Employee Performance of The Automotive Industry In Jakarta, Indonesia.
Authors: Machmed Tun Ganyang Ganyang 
Published: October 2019

This study aims to determine and analyze the impact of organization culture , work environment on employee engagementt and it’s implications on employee performance. This research uses quantititaive approarch. Population of this research is the whole employee of the automotive industry and sample is 86 respondents. The result of this hypothesis test show that (1) Organization culture has a direct, positive, and statistically significant impact on employe engagement; (2)Work environment has a direct, positive and statistically significant on employee engagement; (3) Employee engagement has a direct positive and statistically significant on employee performance.
The Motivation Based on Customer Interaction
Authors: Ahmed Muhammad S , Weisgerber John 
Published: October 2019

Many factors and theories of motivation apply broadly to workers regardless of profession. The prior research has shown that engineers and knowledge workers are highly motivated by intrinsic and non-monetary factors such as challenging work, recognition for good results, and the opportunity for professional growth. Therefore, the nature of their assigned tasks and their ability to complete their work in an efficient and robust way are highly related to motivation. Product Development Engineers (PDEs) play a crucial role in creating value and revenue for companies via the development of useful new products for customers. It is, however, a general observation that PDEs in automotive companies, especially at original equipment manufacturer, OEM, levels, often have minimal or no interaction with the end customer. With the advent of hybrid, electric, and autonomous vehicles, PDE working in the automotive industry, APDEs, has seen a shift in their role and responsibilities from traditional automotive PDEs. APDEs mostly receive customer input indirectly from management or through a marketing organization. This is in contrast to other professionals such as doctors, lawyers, and architects who frequently interact directly with their customers.
This paper presents the finding of qualitative research, examining the relationship between APDEs interaction with customers, and achieving clear customer inputs. The paper investigates differences among various types of APDEs and seeks further insights as to the motivational impact of customer inputs on automotive PDEs. It also probes the question if there are any differences among various types of automotive PDEs when it comes to motivation. The paper concludes that, for some types of APDEs, the lack of customer interaction is a motivational disadvantage while for the others it is not. It also concludes that further research needs to be conducted in order to find the reasons for such discrepancies.
Zum barrierearmen Katalog mit Open-Source-Software: Ein Praxisbericht aus der Universitätsbibliothek Leipzig
Authors: Kazzer Claas 
Published: October 2019

Zusammenfassung
Angesichts knapper personeller und technischer Ressourcen mag es vielen Bibliotheken und Institutionen als gewaltige Anforderung und Hürde erscheinen, ihre Online-Kataloge barrierearm zu gestalten. Dieser Praxisbericht zeigt, wie ein barrierearmer Katalog durch Nutzung von Open-Source-Software und Zusammenarbeit mit einer internationalen Entwicklergemeinschaft sowohl zügig als auch mit knappen Ressourcen umgesetzt werden kann. So können auch kleine Bibliotheken und Institutionen barrierearme Kataloge entwickeln.
Wissen zugänglich für Alle - Barrierefreier Zugang zu Fachliteratur und Studienmaterial
Authors: Imhoff Claudia , Mattert Jana 
Published: October 2019

Zusammenfassung
Der barrierefreie Zugang zu Fachliteratur und Studienmaterialien ist eine wichtige Voraussetzung für ein chancengleiches Studium. Studierende mit unterschiedlichen gesundheitlichen Beeinträchtigungen haben einen Bedarf an barrierefreier Literatur, an barrierefreier Kommunikation sowie an barrierefreien Gebäuden. Nachteilsausgleiche und Unterstützungsangebote in Bibliotheken tragen dazu bei, dass Studierende mit Beeinträchtigung ein Studium erfolgreich absolvieren können.
A generating theorem of punctured surface triangulations with inner degree at least 4
Authors: Chávez María-José , Negami Seiya , Quintero Antonio , Villar-Liñán María Trinidad 
Published: October 2019

Abstract
Given any punctured surface F2, we present a method for generating all of F2 triangulations with inner vertices of degree ≥ 4 and boundary vertices of degree ≥ 3. The method is based on a set of expansive operations which includes the well-known vertex splitting and octahedron addition.
By reversing this method we get a procedure to obtain minimal triangulations by a sequence of intermediate triangulations, all of them within the given family.
Power of meromorphic function sharing polynomials with derivative of it’s combination with it’s shift
Authors: Majumder Sujoy , Saha Somnath 
Published: October 2019

Abstract
In this paper we consider the situation when a power of a transcendental meromorphic function shares non-zero polynomials with derivative of it’s combination with it’s shift. Also we exhibit some examples to fortify the conditions of our results.