bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regulando la nanotecnología
Authors: Saldivar Tanaka Laura 
Published: September 2018

<p class="p1">Este trabajo constituye un modesto acercamiento y aporte al tema de la regulación de la nanotecnología (nt) y nanomateriales (nm’s) o nanoformas,<span class="s2"><sup>1 </sup></span>de su producción, comenzando con una revisión de distintos argumentos del porqué es necesario contar con instrumentos normativos y una breve explicación de las distintas formas en que esto puede suceder (obligatorias, voluntarias, horizontales, verticales, locales, nacionales, internacionales). Posteriormente se hace un apretado recuento de dos de los principales marcos regulatorios en la materia, el de la Comunidad Europea y el de los Estados Unidos de América (EUA). Finalmente, también se hace mención de los esfuerzos que en México se realizan en esta área.<span class="Apple-converted-space"> </span></p>
Mapeamento de processos na dispensação de medicamentos: ferramenta para gestão e melhoria da qualidade
Authors: Gleriano Josué Souza , Roela Sandiely Cristina Ribeiro , Gasparini Liz Vanessa Lupi , Bento Rita De Cássia Pessoa , Furquim Fabiana Cristina , Teixeira Verônica Modolo , Fabro Gisele Caroline Richi 
Published: September 2018

Trata-se de um relato de experiência com objetivo de apresentar o mapeamento e análise do fluxo de medicamentos em uma Unidade de Pronto Atendimento (UPA) da região sudoeste do estado de Mato Grosso - MT, construído na integração ensino com a gestão administrativa do serviço, no ano de 2017. A equipe integrou profissionais da UPA, da farmácia, docentes do curso de administração e enfermagem e discentes dos respectivos cursos. Para mapear os processos definiram-se dois momentos: o primeiro construiu o desenho de fluxo dos medicamentos, o levantamento das coletas de documentos e o segundo a verificação na prática. A análise dos dados resultou no delineamento do fluxo de medicamentos da farmácia do hospital para a UPA, modelo descritivo e fluxograma, que comparado com as normatizações direcionou um relatório sobre pontos de melhorias quanto ao planejamento logístico, reestruturação organizacional e sistema de informatização que carece de instrumentos que poderiam otimizar o tempo, a informação, a logística e a tomada de decisão no trabalho. A experiência permitiu conhecer as peculiaridades e aproximou os atores em uma reflexão-ação-reflexão da prática, além de possibilitar a formalização desse fluxo. Palavras-chave: Administração hospitalar, fluxo de trabalho, medicamentos, organização.
Nampt (Visfatin) Influence on Proliferative Activity of Normal Rat Adrenocortical Cells and Human Adrenal Corticocarcinoma Nci-H295r Cells
Authors: Celichowski Piotr , Jopek Karol , Szyszka Marta , Milecka Paulina , Malendowicz Ludwik K. , Tyczewska Marianna , Ruciński Marcin 
Published: September 2018

Abstract
Nampt (Nicotinamidephosphoribosyltransferase - also known as visfatin/PBEF) is the enzyme that regulates the NAD+ level, therefore influencing many metabolic pathways within the cells. As circulating cytokine, extracellular Nampt (eNampt) exerts pro-inflammatory, pro-chemotactic, pro-angiogenic and insulin-like effects; however the mechanism of eNampt action is still unclear.Earlier studies have shown that eNampt exerts a stimulating effect on the proliferation of many cancer cell lines. However, the effect of this cytokine on cell proliferation in primary culture is little known. Therefore, the aim of the study was to analyse the influence of eNampt on the proliferation of rat adrenocortical cells in primary culture and to investigate similar influence of eNampt on the line H295R of human adrenal corticocarcinoma cells. Proliferation of the examined cells was assessed using the RTCA (Real Time Cell Analyzer) method. The obtained results indicate that eNampt stimulates the proliferation of H295R cells, but does not change the proliferation of cultured rat adrenocortical cells. In primary culture of rat adrenocortical cells, Fk866 (specific Nampt inhibitor) does not modify the rate of proliferation of tested cells. In H295R cells the addition of Fk866 alone inhibits proliferative activity and stimulates apoptosis. Fk866 also inhibits the stimulating effect of eNampt on H295R cell proliferation.
Magnetic-Activated Cell Sorting in Combination with Swim-Up Efficiency Improve Effectivity of Spermatozoa Separation
Authors: Ješeta Michal , Boženková Eliska , Žáková Jana Žá , Ventruba Pavel , Crha Igor , Lousová Eva , Coufalová Petra , Kempisty Bartosz 
Published: September 2018

Abstract
Correct selection of spermatozoa before their using for an assisted reproductive techniques is one of the crucial step in therapy of human infertility. It was previously reported that male factor plays a major role in infertility. Basic semen analyses and standard methods for sperm selection in many cases does not eliminate sufficiently proportion of spermatozoa with genetics defects. Magnetic Activated Cell Sorting (MACS) is a selection method which reduce apoptotic sperm and improve sperm and embryo quality. The aim of our study was the comparison of swim-up method and MACS and their combination. We tested swim-up and MACS alone and treatment of spermatozoa in combination when was is first swim-up and second MACS and vice versa. In this study we evaluated sperm concentration, motility and their DNA integrity before and after separtion methods. On the basis of our results we recommend to use swim-up before MACS method. This approach brings better results in the sperm selection - lower proportion of spermatozoa with fragmented DNA and also it brings better gain of total spermatozoa usable for next IVF or ICSI methods.
EFFECT OF ORGANIC AND INORGANIC NUTRIENTS ON RICE
Authors: V. PRAKASH S. MANIMARAN, 
Published: September 2018

Field experiment was conducted to study the influence of organic and inorganic sources of nutrients on yield parameters of rice (ADT 36). The experiment consists of twelve treatments with three replications viz., T1-100 % Recommended Dose (RD) of NPK kg ha-1 (120:38:38), T2 - RD with soil application of Beema green granules 25 Kg ha-1 at 20 DAT, T3 -75 % RD of NPK kg ha-1 (90:38:38) with soil application of Beema green granules 25 Kg ha-1 at 20 DAT, T4 - RD with foliar spray of panchagavya 3 % at 30 and 45 DAT, T5 - RD with soil application of Beema green granules 25 Kg ha-1 20 DAT with foliar spray of panchagavya 3 % at 30 and 45 DAT, T6 -75 % RD of NPK kg ha-1 (90:38:38) with soil application of Beema green granules 25 Kg ha-1 20 DAT with foliar spray of panchagavya 3 % at 30 and 45 DAT, T7 - RD with foliar spray of Nitrobenzene 750ml ha-1 at 20 DAT, T8 - RD with soil application of Beema green granules 25 Kg ha-1 at 20 DAT with foliar spray of Nitrobenzene 750ml ha-1 at 30 DAT, T9 -75 % RD of NPK kg ha-1 (90:38:38) with soil application of Beema green granules 25 Kg ha-1 at 20 DAT with foliar spray of Nitrobenzene 750ml ha-1 at 30 DAT, T10 - RD with foliar spray of panchagavya 3 % at 30 DAT and foliar spray of Nitrobenzene 750ml ha-1 at 45 DAT, T11 - RD with soil application of Beema green granules 25 Kg ha-1 at 20 DAT and foliar spray of panchagavya 3 % at 30 DAT and foliar spray of Nitrobenzene 750ml ha-1 at 45 DAT, T12 -75 % RD of NPK kg ha-1 (90:38:38) with soil application of Beema green granules 25 Kg ha-1 at 20 DAT and foliar spray panchagavya 3 % at 30 DAT and foliar spray of Nitrobenzene 750ml ha-1 at 45 DAT.
Assessments of non-timber forest products status in the Guraferda district of Ethiopia
Authors: Gessese Belay Haile 
Published: September 2018

Forests and other vegetation resources in Guraferda district offer diverse NTFPs that provide substantial inputs for the livelihoods of the community. Thus, information regarding to the status of NTFPs of the district is vital for proper management of these resources. However, up to date information on the status of non-timber forest products in Guraferda district is found to be lacking. Therefore, this study was conducted to assess the status of NTFPs in the district. Information was collected through household survey and key informant interview. Analysis of data was accomplished through the use of SPSS (version 20) and Microsoft Excel software. Results of the study identified that important NTFPs of the district like honey, forest coffee, forest tuber, forest spices, important health care medicinal plants, Antiaris toxicaria tree with a bark that serves as cloth and sleeping mat preparation, edible forest leaves and fruits, and wild animals for bush meat consumption, that have significantly declined.
PENERAPAN RISK BASED INTERNAL AUDITING: STUDI KASUS PADA PLAN INTERNATIONAL INDONESIA
Authors: Siregar Anitaria , Harahap Siti Nurwahyuningsih 
Published: September 2018

The purposes of this research is to assess risk maturity of Plan International Indonesia to determine whether Plan International Indonesia could implement the Risk Based Internal Auditing (RBIA) approach. Methodology which is used is descriptive methodology with qualitative approach. The Institute of Internal Auditors (2014) suggests the factors that can be taken into account when doing the assessment of risk maturity, and these factors are used for doing the assessment on this research. The result of this research shows the risk maturity of Plan International Indonesia is risk managed stage which mean Plan International Indonesia is ready to implement the RBIA approach. Risk managed also has the meaning that risk register of Plan International Indonesia can be used as the base for the audit planning in this approach. The audit strategy that will be used are management view of risk drives audit plan, assurance being given for the risk management and mitigation, and consulting service to improve risk management. Audit internal team needs to improve their capacity before implementation of this approach and also communication and socialization must be done to entire organization.
Corpus Quality Improvement to Improve the Quality of Statistical Translator Machines (Case Study of Indonesian Language to Java Krama)
Authors: Asparilla Muhammad Gerdy , Sujaini Herry , Nyoto Rudy Dwi 
Published: September 2018

Bahasa merupakan alat komunikasi yang dijadikan sarana untuk berinteraksi dengan masyarakat sekitar.Kemampuan akan penguasaan banyak bahasa tentunya akan mempermudah untuk berinteraksi dengan orang lain dari berbagai daerah yang berbeda. Oleh karena itu, diperlukan penerjemah untuk menambah pengetahuan akan berbagai bahasa yang ada. Mesin Penerjemah Statistik (Statistical Machine Translation) merupakan sebuah pendekatan mesin penerjemah dengan hasil terjemahan yang dihasilkan atas dasar model statistik yang parameter-parameternya diambil dari hasil analisis korpus paralel. Korpus paralel adalah pasangan korpus yang berisi kalimat-kalimat dalam suatu bahasa dan terjemahannya. Salah satu fitur yang digunakan untuk meningkatkan kualitas hasil terjemahan adalah dengan optimasi korpus. Tujuan yang ingin dicapai dalam penelitian ini adalah melakukan untuk melihat pengaruh kualitas korpus dengan memfilter pasangan kalimat-kalimat dengan terjemahan berkualitas. Filter yang digunakan adalah nilai minimal setiap kalimat yang di uji dengan metode Bilingual Evaluation Understudy (BLEU). Pengujian dilakukan dengan membandingkan nilai akurasi hasil terjemahan sebelum dan setelah optimasi korpus. Dari hasil penelitian, penggunaan optimasi korpus dapat meningkatkan kualitas terjemahan untuk mesin penerjemah bahasa Indonesia ke bahasa Jawa krama. Hal itu terlihat dari hasil pengujian dengan menambahkan optimasi korpus pada 15 kalimat uji diluar korpus terdapat peningkatan rata - rata nilai BLEU sebesar 10.53% dan dengan menggunakan 100 kalimat uji yang berasal dari korpus optimasi terdapat peningkatan rata-rata nilai BLEU sebesar 11.63% pada pengujian otomatis serta 0.03% pada pengujian oleh ahli bahasa. Berdasarkan hal tersebut, mesin penerjemah statistik bahasa Indonesia ke bahasa Jawa krama dengan penggunaan fitur optimasi korpus dapat meningkatkan nilai akurasi hasil terjemahan.
IMPLEMENTASI TEAM GAMES TOURNAMENT (TGT) DALAM MENINGKATKAN KERJASAMA DAN HASIL BELAJAR IPA
Authors: Triowathi Noni , Wijayanti Astuti 
Published: September 2018

Penelitian ini bertujuan untuk mengetahui implementasi pembelajaran Team Games Tournament (TGT) dalam meningkatkan kerjasama dan hasil belajar IPA siswa kelas VIII SMPN 12 Yogyakarta. Teknik pengumpulan data menggunakan tes, observasi, angket, dan dokumentasi. Teknik analisis data dilakukan secara kualitatif dan kuantitatif. Instrumen tes hasil belajar IPA dan kerjasama siswa di uji validitas dan relialibilitasnya. Hasil penelitian menunjukkan bahwa rata-rata persentase kerjasama siswa meningkat sebesar 7,09% dari siklus pertama sebesar 75,08 % meningkat menjadi 82,17 % pada siklus kedua. Rata-rata hasil belajar IPA siswa meningkat sebesar 9,28 % dari siklus I 65,30 % meningkat menjadi 75,1%ÃÂ pada siklus kedua.
EFEKTIVITAS EKSTRAK DAUN PEPAYA DALAM PENGENDALIAN KUTU DAUN PADA FASE VEGETATIF TANAMAN TERUNG
Authors: Ramadhona Riski , Djamilah Djamilah , Mukhtasar Mukhtasar 
Published: September 2018

[EFFICACY OF PAPAYA LEAF EXTRACT IN CONTROLLING COTTON APHID DURING VEGEATIVE GROWTH STAGE OF EGGPLANT]. Cotton aphid (Aphis gossypii Glover) can cause serious economic losses in the eggplant production. The application of synthetic pesticides can be effective in controlling the pest but it may not be the best solution for the human health and environment. Botanical pesticides have long been known for their potential as the alternative to synthetic pesticides for crop protection with reduced risk to human health and environmental hazard. Objective of this study was to compare the efficacy of papaya leaf extract solutions in controlling cotton aphid and their effect on the vegetative growth of eggplant. Papaya leaf extract solutions differing in concentration (0%, 10%, 20%, 30%, 40%, and 50%) were sprayed onto aphid infested eggplants to observe the insect mortality, crop damage, and the lethal concentration at LC50 and LC90. The mortality of aphid was significantly increased following the application of papaya leaf extract, with the highest mortality (91.33%) was found on the concentration of 50%. The lethal concentrations of the extract causing 50% (LC50) and 90% (LC90) aphid mortality were 9.98% and 41.99%, respectively. As compared to the control treatment, the crop damage was significantly reduced by the application of the papaya leaf extract solution.
PERTUMBUHAN DAN HASIL PADI SIRANTAU PADA PEMBERIAN BEBERAPA MACAM DAN DOSIS PUPUK KANDANG
Authors: Azalika Ringki Putra , Sumardi Sumardi , Sukisno Sukisno 
Published: September 2018

Salah satu upaya peningkatan produksi padi adalah dengan pengembangan pertanian di lahan – lahan sub optimal yaitu dengan penanaman varietas padi yang toleran kekeringan seperti kultivar sirantau. Penelitian ini bertujuan untuk menentukan jenis dan dosis pupuk kandang yang optimum untuk pertumbuhan dan hasil padi sirantau. Penelitian telah dilaksanakan pada bulan Januari 2016 - Mei 2016 di Kebun Percobaan Fakultas Pertanian Universitas Bengkulu. Penelitian ini merupakan percobaan pot faktorial dua faktor, menggunakan rancangan percobaan RAL (Rancangan Acak Lengkap). Faktor pertama adalah jenis pupuk kandang, yaitu Pupuk kandang Sapi, Pupuk kandang Kambing, Pupuk kandang Ayam. Faktor kedua adalah dosis pupuk kandang, yaitu 5 ton/ha, 10 ton/ha, 15 ton/ha, 20 ton/ha, dan 25 ton/ha, masing – masing perlakuan diulang sebanyak 3 kali. Variabel yang diamati meliputi tinggi tanaman, jumlah anakan total, jumlah anakan produktif, panjang malai, jumlah bulir per malai, persentase bulir bernas, bobot 100 gabah kering, dan bobot gabah kering perumpun. Hasil penelitian menunjukkan bahwa jenis pupuk kandang memberikan pengaruh nyata terhadap variabel jumlah anakan total, jumlah anakan produktif dan bobot gabah kering per rumpun. Pupuk kandang ayam dengan dosis 10 ton/ha memberikan hasil padi terbaik dengan potensi hasil 123,13 g per rumpun (5,77 ton/ha).
+lI/+lU ve +sIz/+sUz EKLERİ TEMELİNDE CİNSİYET
Authors: ÇELİK Ali 
Published: September 2018

Türkçede cinsiyet kategorisi bulunmamasına rağmen, bazı kelimeler
üzerinden cinsiyet varlığı görülmektedir. Bu durum kendi biyolojik
özelliklerinin temelinde ve dil bilgisel ya da sözvarlığı başta olmak üzere
çeşitli biçimlerde olmaktadır.

İsimden isim yapım eklerinden olan +lI/+lU eki varlığı, bulunmayı; +sIz/+sUz
eki ise daha çok yokluğu, yetersizliği bildirmektedir. Bu yapım
ekleri, bazı kelimelere eklenerek sanki
belli bir cinsiyete ait olunduğunu göstermektedir. Bu durum daha çok +lI/+lU ve +sIz/+sUz i.i.y.e.’nin sıfat görevi üstlenmesinden
kaynaklanmaktadır. +lI/+lU ve +sIz/+sUz i.i.y.e. ile verilen örnekler,
kesinlikle dil bilgisel cinsiyetin Türkçede olduğunu kanıtlamamaktadır. Bu
ekler, kelimeyi daha çok isim ve sıfat biçimine sokması nedeniyle cinsiyete
bağlı olduğunu göstermektedir.

Bu makalede +lI/+lU ve +sIz/+sUz i.i.y.e.’nin Türkçe Sözlük
(2011)’te cinsiyet anlamı veren kelimelerle ilişkisi üzerine durulacaktır.
Yapılan genel taramada 69 adet kelime tespit edilmiş,
ardından cinsiyete göre aldığı rol
kapsamında değerlendirilmiştir. Araştırma sonucunda konuyla ilgili detaylı açıklamalar ve
örnekler verilip ardından bazı fikirler belirtilmeye çalışılmıştır.
NURİ BİLGE CEYLAN SİNEMASININ ULUSLARARASI BASINDAKİ ELEŞTİRİLERİ ÜZERİNE BİR SÖYLEM ANALİZİ: BİR ZAMANLAR ANADOLU’DA ÖRNEĞİ
Authors: YETİMOVA Serhat , ASLAN Mustafa 
Published: September 2018

Nuri
Bilge Ceylan gerek Türkiye’de gerekse dünya çapında sinema çevrelerinin
yakından takip ettiği yönetmenlerden biri olarak karşımıza çıkmaktadır. Bu
ilginin nedenleri arasında yönetmenin sunduğu içeriğin evrensel dili olabildiği
gibi bunda sanatın evrenselliği de belirleyici olabilmektedir. Yeni Türk
Sineması içinde dünya sineması ile edebiyatını yakından takip eden bir Türk
yönetmen olarak Nuri Bilge Ceylan, filmlerinde yerel ile evrenseli
buluşturmaktadır. Anadoluluk olgusunu incelediği Bir Zamanlar Anadolu’da filmi
gerek Türkiye’de gerekse yurtdışında oldukça ilgi ile karşılanmıştır. Filminde
bürokrasi, taşralılık, kadın-erkek ilişkileri, ataerkillik ve atalet
fikirlerinin işlendiği gözlenen yönetmenin filmi yurt dışı basınında birçok
eleştiri ve haberin konusu olmuştur. Bu
makale yönetmenin belirtilen filminin dünya basınındaki yansımalarına film
eleştirisi başlığı altında bakmaktadır.
Bu sebeple filmin basın arşivinde yer alan yazılar arasından İngilizce
ve Fransızca basında yazan dokuz farklı ulustan eleştirmenin kaleme aldığı
eleştiri yazılarını söylem analizi yöntemi kullanılarak çözümlemekte ve küresel
modern kültürün etkisindeki eleştirmenlerin Anadolu gibi bir yerelliği eleştirme
biçimlerine bakmaktadır. Araştırmanın sonucunda dokuz farklı ulustan eleştirmen
modernizm ortak paydasında belirtilen filmi eleştirmiş, kendi kültürleri ile
Anadoluluk arasında ilişki kurmak yerine Batı literatürünün kavram haritası
olan feminizm, bürokrasi, Hristiyanlık, realizm, sembolizm, güvenlik, rekabet
ve minimalizm gibi kavramları referans alarak Anadolu’ya bakmayı tercih
etmişlerdir. Bu durum yapılan eleştirilerin bir ölçüde tek tipleşerek
standartlaşmasını beraberinde getirmiş, Anadolu’ya ilişkin özgün fikir ve
deneyimlerin eleştirilerin içinde yer almaması ile sonuçlanmıştır. Tüm bu
veriler küreselleşen dünyanın kültürünün Batı merkezli bir okuma içinde
olduğunu da göstermektedir.
Changes in Lean Muscle Mass Associated with Neoadjuvant Platinum-Based Chemotherapy in Patients with Muscle Invasive Bladder Cancer
Authors: Rimar Kalen J. , Glaser Alexander P. , Kundu Shilajit , Schaeffer Edward M. , Meeks Joshua , Psutka Sarah P. 
Published: September 2018

Background: Baseline sarcopenia or severe lean muscle deficiency is independently associated with increased mortality after cystectomy for muscle-invasive urothelial carcinoma of the bladder (MIUC). The impact of chemotherapy on muscle mass in MIUC patients remains undefined Objectives: To describe preoperative changes in body composition in MIUC patients receiving platinum-based neoadjuvant chemotherapy (NC). Methods: Patients with cT2-4 N0-1 M0 UC of the bladder who received NC were identified. Lumbar skeletal muscle index (SMI, cm2/m2), visceral adipose index (VAI, cm2/m2), and the subcutaneous and intramuscular adipose index (SAI, cm2/m2) were calculated using validated methodology (cross sectional area of skeletal muscle/height2 at L3) from measurement of soft tissue areas on pre- (pre-NC) and post-NC (post-NC) computed tomography. Patients were classified as sarcopenic according to consensus definitions: Male: SMI <55 cm2/m2, Female: SMI <38.5 cm2/m2. Pre-NC and post-NC median body mass index (BMI kg/m2), SMI, and adipose indices were compared. Results: The study cohort consisted of 26 patients, with a median age 70 years, including 7 females (27%). Chemotherapy regimens included dose-dense methotrexate, vinblastine, doxorubicin and cisplatin (31%), gemcitabine/cisplatin (62%) and gemcitabine/carboplatin (3.8%) with a median of 3.5 (range 2–6) cycles. Median pre- and post-NC BMI were 27.1 kg/m2 and 27.2 kg/m2 ( p = 0.36). Median pre- and post-NC SMI were 49.1 cm2/m2 and 44.5 ( p < 0.001) respectively. Median percent change in SMI was –6.4% (range –30% to 10%). Pre-NC, 18 (69%) patients were sarcopenic vs. 21 (81%, p = 0.002) post-NC. Median time between initiation of chemotherapy and cystectomy was 110 days. Conclusions: We observed a significant decrease in lean muscle mass among MIUC patients treated with platinum-based NC prior to cystectomy, with an associated increase in the prevalence of sarcopenia. Patients undergoing NC may benefit from pre-habilitative interventions to mitigate lean muscle loss prior to cystectomy.
Effect of Physical Activity on the Progression of Alzheimer’s Disease: The Clinical Research Center for Dementia of South Korea Study
Authors: Minn Yang-Ki , Choi Seong Hye , Suh Young Ju , Jeong Jee Hyang , Kim Eun-Joo , Kim Jong Hun , Park Kyung Won , Park Moon Ho , Youn Young Chul , Yoon Bora , Choi Seok-Jin , Oh Youn Kyung , Yoon Soo Jin 
Published: September 2018

Background: There is a lack of research on the effects of physical activity (PA) on the progression of Alzheimer’s disease (AD). Objectives: We investigated whether PA is associated with progression of dementia and mortality in AD. Methods: In the present study, 934 patients with mild-to-moderate AD were included. PA was evaluated using a questionnaire written by the caregiver. The outcome measures were the Clinical Dementia Rating-Sum of Boxes (CDR-SB), Seoul-Instrumental Activities of Daily Living (S-IADL), Caregiver-Administered Neuropsychiatric Inventory (CGA-NPI), a global composite score of neuropsychological subtests, and mortality. They were evaluated annually and received a maximum of three follow-up examinations. Results: Between-group differences compared with the no PA group in the change of CDR-SB scores were –0.431 (95% CI = –0.824∼–0.039; p = 0.031) for the moderate PA group (150–750 minutes per week of moderate intensity PA), and –1.148 (–1.656∼–0.639; p < 0.001) for the high PA group (>750 minutes per week). As PA increased, there was a significant trend to slow the rate of increase in the CDR-SB, S-IADL, and CGA-NPI scores. The patients with ≥150 minutes per week for each of non-recreational and recreational PAs had a lower risk of mortality compared to those with <150 minutes per week for each of the PAs (hazard ratio 0.22, 95% CI = 0.05∼0.88; p = 0.033). Conclusion: More PA is associated with slower progression of dementia severity, functional decline, and abnormal behavior, and with a lower risk of mortality in AD.