bluuebunny/crossref_metadata_2025_split huggingface dataset:
lsolated acetabular revisions of articular surface replacement (ASR) XL implants with highly porous titanium cups and Delta bearings
Authors: Castagnini Francesco , Mariotti Federica , Tassinari Enrico , Bordini Barbara , Zuccheri Federica , Traina Francesco 
Published: September 2019

Introduction: Articular surface replacement (ASR) XL implants exhibit higher-than-expected revision rates, blood ion concentrations and soft tissue lesions, making revisions troublesome and potentially unsatisfying. Appropriate techniques and outcomes in ASR XL revisions are rarely documented. The aims of this study were the assessments of pre-revision data, post-revision clinical and radiographic outcomes and ion levels in isolated acetabular ASR XL revisions performed using highly porous titanium cups and Delta ceramic articulations. Methods: 18 isolated acetabular ASR XL revisions in 16 patients were performed using Ti-Por cups (Adler Ortho, Milan, Italy) and Delta bearings (CeramTec, Plochingen, Germany). Pre-revision demographic, clinical, radiological and implant-related features were assessed. Clinical and radiographic parameters (cup positioning, osseointegration) after revisions were evaluated at a minimum follow-up of 5 years. Ion concentrations in blood and urine were collected in pre-revision setting and 1 year after revision. Results: 4 complications occurred in 3 different revisions (16.7%), 1 dislocation, 2 infections, 1 psoas impingement. No re-revision was performed at 5 years (1 scheduled arthroscopy). Good clinical outcomes were achieved (HHS score: 88.3 ± 9.2). All the cups showed reassuring signs of osseointegration (>3 parameters). Blood ion concentrations significantly decreased: patients with Co blood ion concentration over the threshold (7 μg/l) decreased from 76.5% to 0%. No pre-revision or intraoperative data influenced the revision outcomes. Conclusions: Highly porous titanium cups and Delta ceramic articulations provided reliable mid-term clinical and radiographic outcomes in isolated acetabular ASR XL revisions. Ion concentrations significantly decreased. Multicentre prospective controlled studies are required to confirm these preliminary outcomes.
Cardiovascular diseases risk factors among adult diabetic patients in eastern Ethiopia
Authors: Abdosh Tekabe , Weldegebreal Fitsum , Teklemariam Zelalem , Mitiku Habtamu 
Published: September 2019

Objective The aim of this study was to determine the magnitude of cardiovascular disease risk factors among adult diabetic patients at Hiwot Fana Specialized University Hospital and Jugal Hospital, eastern Ethiopia. Methods An institutional based cross sectional study was conducted on a total of 416 study participants (age ≥18 years) from February to March 2017. Data were collected using: structured questionnaires, measurements of weight, height, and blood pressure, and laboratory examination of blood lipids (total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein cholesterol) and fasting blood glucose. Data were analyzed using SPSS version 16.0 software packages. The association of cardiovascular disease risk factors with diabetes type, age, and sex was assessed by chi-square test. Result The mean age of study participants was 52 years and 44% were male. Dyslipidemia (90.6%), physical inactivity (76%), and hypertension (62.7%) were the most common cardiovascular disease risks factors identified among diabetic patients. It was also observed that 68.5% of the study participants had uncontrolled blood glucose level. Hypertension was significant in patients over 65 compared to those ≤65 years of age (p < 0.023). Females were considered to be significantly physically inactive compared to males (p < 0.001). Conclusion Dyslipidemia is the most common risk factor of CVD in individuals with Types 1 and 2 diabetes mellitus. Identification and treatment of lipid abnormalities is very important. Controlling hypertension among older patients and lifestyle modification among female diabetic patients are also recommended.
Factors associated with cerebral edema in children under 5 years of age admitted in an intensive care unit and their outcome
Authors: Islam Shamin , Sarmin Monira , Ahmed Tahmeed , Afroze Farzana , Chisti Mohammod Jobayer 
Published: September 2019

Objective: We aimed to evaluate risk factors and outcome of cerebral edema in children with diarrhea. Methods: In this retrospective chart analysis, data of all diarrheal children under 5 years of age having convulsion and admitted in intensive care unit were retrieved from an electronic medical record system of Dhaka Hospital of International Centre for Diarrhoeal Disease Research, Bangladesh, from 1st January 2011 to 31st December 2016. Comparison of clinical and laboratory characteristics was made between children with (cases = 22) and without cerebral edema (controls = 66). Results: Cases more often had a fatal outcome than controls (36% vs 8%, p = 0.003). In logistic regression analysis, after adjusting for potential confounders, the cases were independently associated with respiratory distress (odds ratio = 5.5, confidence interval = 1.55–19.62, p = 0.008), severe sepsis (odds ratio = 4.6, confidence interval = 1.24–16.77, p = 0.022), and severe malnutrition (odds ratio = 0.16, confidence interval = 0.04–0.74, p = 0.019). A rapid drop (>0.5 mmol/L per hour) in serum sodium did not have any impact on developing cerebral edema (p = 0.090). Conclusion: Identification of simple clinical predictors may help in the early treatment of cerebral edema that may further help in reducing deaths in such children especially in resource-poor settings. However, further research with prospective design is needed to consolidate our observation.
Cytokine release after gluten ingestion differentiates coeliac disease from self‐reported gluten sensitivity
Authors: Tye‐Din Jason A , Skodje Gry I , Sarna Vikas K , Dzuris John L , Russell Amy K , Goel Gautam , Wang Suyue , Goldstein Kaela E , Williams Leslie J , Sollid Ludvig M , Lundin Knut EA , Anderson Robert P 
Published: September 2019

BackgroundDiagnosing coeliac disease (CD) in patients on a gluten‐free diet (GFD) is difficult. Ingesting gluten elevates circulating interleukin (IL)‐2, IL‐8 and IL‐10 in CD patients on a GFD.ObjectiveWe tested whether cytokine release after gluten ingestion differentiates patients with CD from those with self‐reported gluten sensitivity (SR‐GS).MethodsAustralian patients with CD (n  = 26) and SR‐GS (n  = 18) on a GFD consumed bread (estimated gluten 6 g). Serum at baseline and at 3 and 4 h was tested for IL‐2, IL‐8 and IL‐10. Separately, Norwegian SR‐GS patients (n  = 49) had plasma cytokine assessment at baseline and at 2, 4 and 6 h after food bars containing gluten (5.7 g), fructan or placebo in a previous double‐blind crossover study.ResultsGluten significantly elevated serum IL‐2, IL‐8 and IL‐10 at 3 and 4 h in patients with CD but not SR‐GS. The highest median fold‐change from baseline at 4 h was for IL‐2 (8.06, IQR: 1.52–24.0; P  < 0.0001, Wilcoxon test). The two SR‐GS cohorts included only one (1.5%) confirmed IL‐2 responder, and cytokine responses to fructan and placebo were no different to gluten. Overall, cytokine release after gluten was present in 22 (85%) CD participants, but 2 of the 4 non‐responders remained clinically well after 1 y on an unrestricted diet. Hence, cytokine release occurred in 22 (92%) of 24 ‘verified’ CD participants.ConclusionsGluten challenge with high‐sensitivity cytokine assessment differentiates CD from SR‐GS in patients on a GFD and identifies patients likely to tolerate gluten reintroduction. Systemic cytokine release indicating early immune activation by gluten in CD individuals cannot be detected in SR‐GS individuals.
ERCP in babies: Low risk of post‐ERCP pancreatitis – results from a multicentre survey
Authors: Goetz Martin , Andersen Philipp , Bergman Jacques , Frei Nicola , Schmidt Arthur , Kähler Georg , Martus Peter , Dechêne Alexander 
Published: September 2019

Background and aimsEndoscopic retrograde cholangiopancreatography (ERCP) is rarely performed in newborns, and the risk of post‐ERCP pancreatitis (PEP) has not been defined in this age group. We therefore performed a European multicentre analysis of PEP rates and risk factors in children aged ≤1 year.Patients and methodsBased on a sample size estimation, 135 consecutive ERCPs in 126 children aged ≤1 year were evaluated from five European centres, and the first ERCP per child analysed. All ERCPs and clinical reports were reviewed manually for PEP and associated risk factors. All ERCPs were performed by endoscopists with high ERCP expertise.ResultsNo PEP was observed (0/126, 0.0%, CI 0–2.9%) despite the formal presence of multiple risk factors and despite lack of PEP prophylaxis (except one patient having received a pancreatic duct stent). The PEP rate was significantly lower than the PEP rate expected in adults with similar risk factors.ConclusionsERCP in children aged ≤1 year is safe in terms of PEP. The PEP risk is significantly lower in children aged ≤1 year than in adults, therefore no PEP prophylaxis seems to be needed in young children. Risk factors from adults may not apply to children under 1 year. Reluctance to perform diagnostic ERCP in suspected biliary anomalies should not be based on presumed PEP risk.
Use of Blood Flow Restriction Training for Postoperative Rehabilitation
Authors: Wilkinson Brandon G. , Donnenwerth Jesse J. , Peterson Andrew R. 
Published: September 2019

Abstract
Blood flow restriction (BFR) training is commonly used to induce muscle hypertrophy and strength and is gaining popularity as a modality for treatment of musculoskeletal conditions and postoperative rehabilitation. This article reviews the current literature on BFR as a rehabilitative tool, identifies gaps in the literature, and reports the authors experience using BFR in the postoperative environment.
Transgender Policy in Sport, A Review of Current Policy and Commentary of the Challenges of Policy Creation
Authors: Ingram Benjamin James , Thomas Connie Lynn 
Published: September 2019

Abstract
This review starts with a brief history of sex policy in sport followed by an exploration of the current state of transgender sport policies. Transgender in sport, from the high school to the professional level, is a frequent news topic. Fairness in women's athletics is at the center of transgender sport policy deliberations and public debate. Despite a long history of policy attempts and revisions, the female category in sport is not precisely and universally established, complicating transgender athlete policy development. Scientific evidence is scant on fairness for transgender athletes. For a variety of social factors, many transgender athletes do not have a positive experience in sports and the younger is the athlete the more challenging it becomes to create inclusive rules. Challenges remain in making competition rules fair, but inclusive, so that transgender athletes participate in sport. The medical and scientific community will continue to provide key input.
Como disseminar a linguagem dos dados
Authors: Becker João Luiz , Diniz Eduardo Henrique 
Published: September 2019

Todos podem aprender as habilidades de ler, escrever e compreenderdados, desde que se mudem os paradigmas de ensino de data literacy.O aprendizado centrado no participante e na prática quotidiana ajuda a valorizar as ferramentas analíticas de baixo para cima, em um processo de “aprender fazendo”.
Precio del carbón y dinámica laboral en Valledupar
Authors: Arango Luis E , Flórez Luz A , Olarte-Delgado María A 
Published: September 2019

En esta investigación se realiza un análisis del mercado laboral en Valledupar en el periodo 2007-2017 encontrando que, a partir de la caída de los precios del carbón en 2014, este se deterioró de manera significativa; así, durante este periodo creció la tasa de desempleo, especialmente entre los más educados, las mujeres y los jóvenes. Los resultados econométricos confirman que los cambios en los precios del carbón tienen un efecto positivo en la participación laboral y en los salarios reales; adicionalmente, se encuentra que los retornos a la educación superior en Valledupar son menores en comparación con otras ciudades del país.
A FORÇA DA DERIVA: NARRAR E HUMANIZAR / The force of deriva: narrating and humanizing
Authors: Gonçalves Quelhas Iza Terezinha 
Published: September 2019

Este artigo tece reflexões sobre o ensaio O direito à literatura (2004), de Antonio Candido, com ênfase no ensino da literatura. O ensaio foi apresentado em evento promovido pela Comissão de Justiça e Paz da Arquidiocese de São Paulo, em 1988. No texto, destaca-se a potência que o autor identifica na literatura para ultrapassar a barbárie que, naquele momento histórico, no Brasil, ainda se mantinha presente, apesar de reconhecer certo constrangimento social, pelo menos, a qualquer elogio público dessa barbárie. Candido considerava que o ensino da literatura possui várias missões, uma delas, humanizar. A questão que se pretende discutir é a continuidade ou não da expectativa de potência, um “sonho acordado das civilizações” (2004, p. 175), na contemporaneidade, a partir de um breve estudo sobre a importância da lenda, no contexto cultural brasileiro. A lenda que serve de base para este trabalho sinaliza caminhos que colocam a função humanizadora no centro do dizer – literatura oral ou escrita – e, no âmbito do ensino, promove o conhecimento de mundo no presente e no passado, sem desconhecer as possibilidades de construção do futuro, inclusive aquelas de acesso a bens culturais, como o são as bibliotecas de domínio público, entre outras iniciativas que podem concretizar o “direito à literatura” pelo acesso universal.
Relationship between serum ferritin and zinc levels in patients with major thalassemia
Authors: Yeni Hervita , Yani Finny Fitry , Izzah Amirah Zatil , Lubis Gustina 
Published: September 2019

Background In thalassemia patients, reduced zinc absorption results from increased serum iron due to repeated blood transfusions, increased iron absorption due to ineffective erythropoiesis, and competitive inhibition between iron and zinc in binding to transferrin, a means of transporting both types of minerals in the blood. Few studies have been done to examine zinc levels in thalassemia patients and its relationship with ferritin.
Objective To compare serum zinc in thalassemia patients and healthy controls and to assess for a possible correlation between serum ferritin and zinc in thalassemia patients.
Methods This cross-sectional study in 68 subjects was done from October 2016 to August 2017. Serum ferritin measured by chemiluminescence immunoassay and serum zinc by inductively coupled plasma mass spectrometry (ICP-MS). Wilcoxon test was used to analyze for differences between serum zinc in thalassemia patients and controls. Spearman’s correlation test was used to analyze for a possible correlation between ferritin and serum zinc in thalassemia patients.
Results There were 34 patients with thalassemia and 34 healthy control subjects. The median serum zinc was 119.34 µg/dL (IQR=71.27) in the thalassemia group and 120.08 µg/dL (IQR=26.28) in the control group (P=0.36). There was no significant correlation between serum ferritin and zinc in thalassemic children (r=-0.023; P=0.895).
Conclusion There is no significant difference in serum zinc levels between thalassemic children and healthy controls. There is no significant correlation between serum ferritin and zinc in thalassemic children.
Narrative Authority, Theory in the Flesh, and the Fight overThe Death and Life of Marsha P. Johnson
Authors: Calafell Bernadette Marie 
Published: September 2019

AbstractThis article explores the controversy surrounding David France’s documentary, The Death and Life of Marsha P. Johnson, which premiered on Netflix in October 2017. Examining both France, and trans activist and filmmaker Tourmaline’s statements that France stole her ideas and work from her project, Happy Birthday Marsha!, this article unpacks the fight over narrative authority. Using queer and feminist of color theories based in theories of the flesh, I argue that through the whitening of Johnson’s narrative and framing her as a victim by France, as well as claims to narrative authority by Tourmaline and Mariah Lopez, trans kin of Johnson, the controversy points to the limits of queer politics for understanding the experiences of transwomen of color on their own terms. Thus, I argue for the necessity of a trans* analytic as a space of radical coalition building.
First Record of The Burrowing Goby Trypuchen vagina from Pangpang Bay, Indonesia
Authors: Andriyono Sapto , Masithah Endang Dewi , Pramono Heru , Suciyono Suciyono 
Published: September 2019

The burrowing goby, Trypauchen vagina, is recorded for the first time from the Pangpang Bay of Banyuwangi, Indonesia. Types of fish T. vagina is a type that has not published in Indonesia. This fish was caught using trap net in waters Pangpang Bay, which is an essential area in Banyuwangi, East Java. The description of the morphology and fish habitat conditions shows that the region has a diversity of fish resources that need attention. This goby fish has a local name as fish bedhul picek due to the sense of sight on these fish as if it does not work. Eyes covered by skin and socket head section was not found their eyeballs. The body of the specimens is elongate and reddish-pink in fresh specimens in coloration. There is no barbel on the chin. Cycloid scales are present on the whole body except for the head. Muncar people commonly consume T.vagina. This fish has been food sources in several regions but uncommon at several local markets in Indonesia. The T.vagina inhabit at Pangpang Bay as the bay, which has the high primary productivity of these waters due to sufficient nutrient support. Enrichment of nutrient comes from the run-off land and also the input of the number of fishing activity (embankment). An earlier report said that this fish found in waters Banyu Asin, Palembang, Sumatra, Indonesia. It also confirms that the fish found in this study are also living in a mud substrate that is reasonably smooth with right mangrove conditions around the bay, which close to Alas Purwo National Park.
Commercialization of Irish moss aquaculture: the Canadian experience
Authors: Craigie James S. , Cornish M. Lynn , Deveau Louis E. 
Published: September 2019

Abstract
Irish moss traditionally has been valued for its hydrocolloid composition. Recognition that natural harvests would not meet the expected demands for its biomass led to experimental pilot-scale cultivation based on principles used in agriculture. Innovative technologies and systems for aquaculture management were devised when those from agriculture or mariculture were not directly transferrable. Periods of rapid progress and of consolidation due to disruptive external events were encountered, a cycle not uncommon during the introduction of a new technology. Certain key decisions in the background matrix that ultimately led to Irish moss cultivation are reviewed together with an overview of the main critical events that affected progress. The Chondrus crispus aquaculture as practiced today is essentially a modified form of precision agriculture operating year-round with c. 3.4 ha of on-land culture tanks and up to 75 employees during the peak season. Beginning with new Irish moss seedstock from the library/nursery, the crop is generated through a closely controlled, vertically integrated system of cultivation that after approximately 18 months increases the biomass more than 50,000-fold. After harvesting it is processed into the final food-grade products to meet the stringent demands of the export market.
The effects of soy on scopolamine-induced spatial learning and memory impairments are comparable to the effects of estradiol
Authors: Marefati Narges , Mokhtari-Zaer Amin , Beheshti Farimah , Karimi Sareh , Mahdian Zahra , Khodamoradi Mehdi , Hosseini Mahmoud 
Published: September 2019

Abstract

Background
Modulatory effects of soy extract and estradiol on the central nervous system (CNS) have been reported. The effect of soy on scopolamine-induced spatial learning and memory in comparison to the effect of estradiol was investigated.

Materials and methods
Ovariectomized rats were divided into the following groups: (1) control, (2) scopolamine (Sco), (3) scopolamine-soy 20 (Sco-S 20), (4) scopolamine-soy 60 (Sco-S 60), (5) scopolamine-estradiol 20 (Sco-E 20) and (6) scopolamine-estradiol 60 (Sco-E 60). Soy extract, estradiol and vehicle were administered daily for 6 weeks before training in the Morris water maze (MWM) test. Scopolamine (2 mg/kg) was injected 30 min before training in the MWM test.

Results
In the MWM, the escape latency and traveled path to find the platform in the Sco group was prolonged compared to the control group (p < 0.001). Treatment by higher doses of soy improved performances of the rats in the MWM (p < 0.05 – p < 0.001). However, treatment with both doses of estradiol (20 and 60 μg/kg) resulted in a statistically significant improvement in the MWM (p < 0.01 – p < 0.001). Cortical, hippocampal and serum levels of malondialdehyde (MDA), as an index of lipid peroxidation, were increased which was prevented by soy extract and estradiol (p < 0.001). Cortical, hippocampal as well as serum levels of the total thiol, superoxide dismutase (SOD) and catalase (CAT) in Sco group were lower than the control group (p < 0.001) while they were enhanced when the animals were treated by soy extract and estradiol (p < 0.01 – p < 0.001).

Conclusions
It was observed that both soy extract and estradiol prevented learning and memory impairments induced by scopolamine in ovariectomized rats. These effects can be attributed to their protective effects on oxidative damage of the brain tissue.
Whole exome sequencing identified a heterozygous KCNJ2 missense variant underlying autosomal dominant familial hypokalemic periodic paralysis in a Pakistani family
Authors: Ullah Aman , Khan Ranjha , Naeem Muhammad 
Published: September 2019

AbstractBackgroundFamilial hypokalemic periodi9c paralysis (hypoKPP) is a rare autosomal dominant disorder characterized by episodic paralytic attacks caused by fall in blood potassium.CACNA1S,SCN4AorKCNJ2variants can cause hypoKPP.Case presentationWe investigated a Pakistani family affected with autosomal dominant familial hypoKPP through whole exome sequencing (WES). A heterozygousKCNJ2missense variant c.919A > G was found segregating with the disease phenotype in the family.ConclusionsTheKCNJ2missense variant is the likely cause of the disorder in the affected family. The finding should help improve antenatal screening and genetic counselling of this family.