bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interest rates forecasting and stress testing in India: a PCA-ARIMA approach
Authors: Mallick Aswani Kumar , Mishra Alok Kumar 
Published: April 2019

AbstractIn the Basel III era, measuring, managing, mitigating and forecasting interest rate risk has become significant. In the first study of its kind, this paper develops a principal component analysis-based forecasting of interest rates of different maturities and stress testing approach in a univariate auto-regressive integrated moving average (ARIMA) framework in the context of India. Debating the existence of multiple representations of interest rates in the Indian market, the study broke down all the short-term, as well as long-term interest rates to derive the optimal principal component of unique interest rates. These unique interest rates are further exercised to forecast the future interest rates through the ARIMA model. The rolling average method was applied to the recently created Indian volatility index (VIX) to place the stress points. The model performance was examined over this stress point of building multiple scenario analysis. The study found that ARIMA (2-1-1) forecasting model of interest rates produced a better forecast result, both in the case of in-sample and out-of-sample performances as well as in stress periods. From the forecasting results, the study found that the proportionate gain in yield is higher as the maturity increases. By examining the stress period on the basis of eight quarters (2007: Q4 of 2009: Q3) rolling average on Indian volatility Indices, the survey concluded that the Indian economy will reach a stable situation signalled by less volatile interest rates post the second quarter of 2018.
We Have Never Been Anti-Exceptionalists
Authors: Nelson Dana D 
Published: April 2019

AbstractThe project of repudiating the exceptionalism associated with the Cold War–era founders of American studies came at the same academic moment as the canon debates—they both started in the mid-1980s. They are twinned countercultural movements, and at their origin they were explicitly interrelated. We’ve debunked American exceptionalism, but we’re still practically glued to the old-fashioned canon—at least where the nineteenth century is concerned. This essay takes up the incompletion at the heart of what began as a conjoined movement against the exceptionalisms of national and literary canons, arguing that our attachment to canonical authors indexes the larger insolvency of our anti-exceptionalist project. It argues for a different critical methodology, one grounded in self-criticism, incompletion, and imperfection.
Do Changes in Material Circumstances Drive Support for Populist Radical Parties? Panel Data Evidence from the Netherlands during the Great Recession, 2007–2015
Authors: Gidron Noam , Mijs Jonathan J B 
Published: April 2019

AbstractPolitical developments since the 2008 financial crisis have sparked renewed interest in the electoral implications of economic downturns. Research describes a correlation between adverse economic conditions and support for radical parties campaigning on the populist promise to retake the country from a corrupt elite. But does the success of radical parties following economic crises rely on people who are directly affected? To answer this question, we examine whether individual-level changes in economic circumstances drive support for radical parties across the ideological divide. Analysing eight waves of panel data collected in the Netherlands, before, during, and after the Great Recession (2007–2015), we demonstrate that people who experienced an income loss became more supportive of the radical left but not of the radical right. Looking at these parties’ core concerns, we find that income loss increased support for income redistribution championed by the radical left, but less so for the anti-immigration policies championed by the radical right. Our study establishes more directly than extant research the micro-foundations of support for radical parties across the ideological divide.
An evaluation of workplace choir singing amongst Health Service staff in Ireland
Authors: Moss Hilary , O’Donoghue Jessica 
Published: April 2019

Abstract
This paper explores the well-being [‘well-being’ and ‘wellbeing’ are used interchangeably in the literature. Well-being is used in this paper (except in the reference list where exact wording is maintained)] benefits of participation in a workplace choir for health service staff. A mixed method study, this project combines quantitative measures of work engagement, perceived stress, resilience levels and work absences with qualitative interviews with choir participants. It is the first study of workplace choirs in Ireland and one of very few studies internationally that research health service staff choirs. There is some preliminary evidence of benefits that choir attendance may increase positive perception of workers’ mental health as well as effect depression rates. However, evidence is limited quantitatively and difficulties in measuring the health benefits of arts interventions are noted. Qualitative data, however, confirms previous study findings, namely that a workplace choir can promote social connectedness, enjoyment at work and staff engagement. Work place choir was also noted to appeal mainly to a limited demographic of work place staff and people with relatively positive health and well-being. Efforts must be made to engage staff from lower socio-economic backgrounds, diverse cultural backgrounds and male staff in work place health promotion activities, as these groups were found less likely to join a work place choir. Given the low cost and low risk of this activity, and the qualitative benefits reported, it is recommended to continue to develop and evaluate health service workplace choirs.
Youth physical health and years in American homeschools: are they related?
Authors: Kabiri Laura S , Butcher Allison , Brewer Wayne , Ortiz Alexis 
Published: April 2019

Abstract
Homeschooling is a growing trend in the USA and abroad with both reported consequences and benefits to youth physical health. The purpose of this study was to examine whether changes in youth physical health could be related to the number of years a student spends in homeschool. Body composition (body mass index and body fat), muscular fitness (lower extremity, abdominal and upper extremity) and cardiorespiratory fitness (Progressive Aerobic Capacity Endurance Run) were assessed in 211 youth ages 5–17. Data analysis showed weak or non-significant relationships between years in homeschool and all aspects of youth physical health. Time spent in homeschool is weakly or not at all related to multiple aspects of youth physical health. Parents and policy makers should not be concerned with detrimental physical health effects of homeschooling on youth.
Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar dynein function in primary cilia
Authors: King Ashleigh , Hoch Nicolas C , McGregor Narelle E , Sims Natalie A , Smyth Ian M , Heierhorst Jörg 
Published: April 2019

AbstractMutations in subunits of the cilia-specific cytoplasmic dynein-2 (CD2) complex cause short-rib thoracic dystrophy syndromes (SRTDs), characterized by impaired bone growth and life-threatening perinatal respiratory complications. Different SRTD mutations result in varying disease severities. It remains unresolved whether this reflects the extent of retained hypomorphic protein functions or relative importance of the affected subunits for the activity of the CD2 holoenzyme. To define the contribution of the LC8-type dynein light chain subunit to the CD2 complex, we have generated Dynll1-deficient mouse strains, including the first-ever conditional knockout (KO) mutant for any CD2 subunit. Germline Dynll1 KO mice exhibit a severe ciliopathy-like phenotype similar to mice lacking another CD2 subunit, Dync2li1. Limb mesoderm-specific loss of Dynll1 results in severe bone shortening similar to human SRTD patients. Mechanistically, loss of Dynll1 leads to a partial depletion of other SRTD-related CD2 subunits, severely impaired retrograde intra-flagellar transport, significant thickening of primary cilia and cilia signaling defects. Interestingly, phenotypes of Dynll1-deficient mice are very similar to entirely cilia-deficient Kif3a/Ift88-null mice, except that they never present with polydactyly and retain relatively higher signaling outputs in parts of the hedgehog pathway. Compared to complete loss of Dynll1, maintaining very low DYNLL1 levels in mice lacking the Dynll1-transcription factor ASCIZ (ATMIN) results in significantly attenuated phenotypes and improved CD2 protein levels. The results suggest that primary cilia can maintain some functionality in the absence of intact CD2 complexes and provide a viable animal model for the analysis of the underlying bone development defects of SRTDs.
Metabolic status in children and its transitions during childhood and adolescence—the IDEFICS/I.Family study
Authors: Börnhorst Claudia , Russo Paola , Veidebaum Toomas , Tornaritis Michael , Molnár Dénes , Lissner Lauren , Marild Staffan , De Henauw Stefaan , Moreno Luis A , Intemann Timm , Wolters Maike , Ahrens Wolfgang , Floegel Anna 
Published: April 2019

Abstract

Background
This study aimed to investigate metabolic status in children and its transitions into adolescence.

Methods
The analysis was based on 6768 children who participated in the European IDEFICS/I.Family cohort (T0 2007/2008, T1 2009/2010 and/or T3 2013/2014; mean ages: 6.6, 8.4 and 12.0 years, respectively) and provided at least two measurements of waist circumference, blood pressure, blood glucose and lipids over time. Latent transition analysis was used to identify groups with similar metabolic status and to estimate transition probabilities.

Results
The best-fitting model identified five latent groups: (i) metabolically healthy (61.5%; probability for group membership at T0); (ii) abdominal obesity (15.9%); (iii) hypertension (7.0%); (iv) dyslipidaemia (9.0%); and (v) several metabolic syndrome (MetS) components (6.6%). The probability of metabolically healthy children at T0 remaining healthy at T1 was 86.6%; when transitioning from T1 to T3, it was 90.1%. Metabolically healthy children further had a 6.7% probability of developing abdominal obesity at T1. Children with abdominal obesity at T0 had an 18.5% probability of developing several metabolic syndrome (MetS) components at T1. The subgroup with dyslipidaemia at T0 had the highest chances of becoming metabolically healthy at T1 (32.4%) or at T3 (35.1%). Only a minor proportion of children showing several MetS components at T0 were classified as healthy at follow-up; 99.8% and 88.3% remained in the group with several disorders at T1 and T3, respectively.

Conclusions
Our study identified five distinct metabolic statuses in children and adolescents. Although lipid disturbances seem to be quite reversible, abdominal obesity is likely to be followed by further metabolic disturbances.
Recycling and reuse of solid wastes; a hub for ecofriendly, ecoefficient and sustainable soil, concrete, wastewater and pavement reengineering
Authors: Onyelowe Kennedy Chibuzor , Bui Van Duc , Ubachukwu Obiekwe , Ezugwu Charles , Salahudeen Bunyamin , Nguyen Van Manh , Ikeagwuani Chijioke , Amhadi Talal , Sosa Felix , Wu Wei , Ta Duc Thinh , Eberemu Adrian , Pham Duc Tho , Barah Obinna , Ikpa Chidozie , Orji Francis , Alaneme George , Amanamba Ezenwa , Ugwuanyi Henry , Sai Vishnu , Kadurumba Chukwuma , Subburaj Selvakumar , Ugorji Benjamin 
Published: April 2019

AbstractEcofriendly, ecoefficient and sustainable civil engineering work has been research with emphasis on adapting the byproducts of solid waste recycling and reuse to achieving infrastructural activities with low or zero carbon emission. The direction combustion model, the solid waste incinerator caustic soda oxides of carbon entrapment model (SWI-NaOH-OCEM) developed by this research has achieved a zero carbon release. This research adopted the literature search method to put together research results of previous works relevant to the aim of this present work. It has been shown that CO and CO2 emissions can be contained during the derivation of alternative or supplementary cementing materials used in the replacement of ordinary Portland cement in civil engineering works. In the overall assessment of the present review work has left the environment free of the hazards of CO and CO2 emissions. It was shown that these supplementary cementing materials derived from solid wastes improve the engineering properties of treated soft clay and expansive soils, concrete, and asphalt. Bio-peels, another form solid waste has been established as a good detoxificant used in treating wastewater. It has been shown that solid waste recycling and reuse is a hub to achieving ecofriendly, ecoefficient and sustainable infrastructural development on the global scale.
Double-Edged Role of Interleukin 17A in Streptococcus pneumoniae Pathogenesis During Influenza Virus Coinfection
Authors: Ambigapathy Ganesh , Schmit Taylor , Mathur Ram Kumar , Nookala Suba , Bahri Saad , Pirofski Liise-anne , Khan M Nadeem 
Published: April 2019

AbstractBackgroundWe sought to determine the role of host interleukin 17A (IL-17A) response against colonizing Streptococcus pneumoniae, and its transition to a pathogen during coinfection with an influenza virus, influenza A H1N1 A/Puerto Rico/8/1934 (PR8).MethodWild-type (WT) C57BL/6 mice were intranasally inoculated with S. pneumoniae serotype 6A to establish colonization and later infected with the influenza strain, PR8, resulting in invasive S. pneumoniae disease. The role of the IL-17A response in colonization and coinfection was investigated in WT, RoRγt−/− and RAG1−/− mice with antibody-mediated depletion of IL-17A (WT) and CD90 cells (RAG1−/−).ResultsRAG1−/− mice did not clear colonization and IL-17A neutralization impaired 6A clearance in WT mice. RoRγt−/− mice also had reduced clearance. S. pneumoniae–PR8 coinfection elicited a robust IL-17A response in the nasopharynx; IL-17A neutralization reduced S. pneumoniae invasive disease. RoRγt−/− mice also had reduced S. pneumoniae disease in a coinfection model. Depletion of CD90+ cells suppressed the IL-17A response and reduced S. pneumoniae invasion in RAG1−/− mice.ConclusionOur data show that although IL-17A reduces S. pneumoniae colonization, coinfection with influenza virus elicits a robust innate IL-17A response that promotes inflammation and S. pneumoniae disease in the nasopharynx.
The power transition and the US response to China’s expanded soft power
Authors: Huang Wei-hao , Lien Donald , Xiang Jun 
Published: April 2019

Abstract
Many scholars have examined how the United States should respond to a rising non-democratic China. Contrary to the well-debated hard power domain, little attention has been devoted to China’s soft power. This study is arguably the first to systematically investigate the US response to the establishment of Confucius Institutes—China’s global initiative to expand soft power. We argue that the US decision to establish Confucius Institutes is influenced by both macro- and micro-level variables. At the macro-level, as suggested by the power transition theory, the United States is more likely to accommodate Confucius Institutes when China shows a higher level of satisfaction with the United States. At the micro-level, US universities and state governments host Confucius Institutes due to budget saving and community engaging. Our analysis sheds light on how the United States makes trade-offs when confronting China’s expanded soft power, and it provides yet another prominent example of money buying influence in international relations.
Grazing alters environmental control mechanisms of evapotranspiration in an alpine meadow of the Tibetan Plateau
Authors: An Tingting , Xu Mingjie , Zhang Tao , Yu Chengqun , Li Yingge , Chen Ning , Zu Jiaxing , Li Junxiang , Zhu Juntao , Sun Yi , Zhao Tingting , Yu Guirui 
Published: April 2019

Abstract

Aims
Evapotranspiration (ET) is an important component of the terrestrial water cycle and is easily affected by external disturbances, such as climate change and grazing. Identifying ET responses to grazing is instructive for determining grazing activity and informative for understanding the water cycle.

Methods
This study utilized 2 years (2014 and 2017) of eddy covariance data to test how grazing regulated ET for an alpine meadow ecosystem on the Tibetan Plateau (TP) by path analysis.

Important Findings
Radiation dominated ET with a decision coefficient of 64–74%. The soil water content (SWC) worked as the limiting factor in the fenced site. However, in the grazing site, the limiting factor was the vapor pressure deficit (VPD). Grazing had large effects on ET because it greatly affected the water conditions. The SWC and VPD were enhanced by 14.63% and 4.36% in the grazing site, respectively. Therefore, sufficient water was supplied to ET, especially during drought, and strengthened the transpiration pull. As a result, a favorable micrometeorological environment was created for ET. Grazing shifted the limiting factor of ET from the SWC to VPD, which weakened the limiting effect of the water conditions on ET and advanced the ET peak time. In addition, grazing altered the compositions of ET by changing the community structure, which directly resulted in an increased ET. In summary, grazing enhanced ET through altering the community structure and micrometeorological environments. The findings of this study further improve our understanding of the driving mechanisms of grazing on ET and will improve our predictions for the global water cycle.
The molecular gas properties in the gravitationally lensed merger HATLAS J142935.3–002836
Authors: Messias Hugo , Nagar Neil , Zhang Zhi-Yu , Oteo Iván , Dye Simon , Ibar Eduardo , Timmons Nicholas , van der Werf Paul , Riechers Dominik , Eales Stephen , Ivison Rob , Maresca Jacob , Michałowski Michał J , Yang Chentao 
Published: April 2019

ABSTRACT
Follow-up observations of (sub-)mm-selected gravitationally lensed systems have allowed a more detailed study of the dust-enshrouded phase of star formation up to very early cosmic times. Here, the case of the gravitationally lensed merger in HATLAS J142935.3–002836 (also known as H1429−0028; zlens = 0.218, zbkg = 1.027) is revisited following recent developments in the literature and new Atacama Pathfinder EXperiment (APEX) observations targeting two carbon monoxide (CO) rotational transitions Jup = 3 and 6. We show that the line profiles comprise three distinct velocity components, where the fainter high velocity one is less magnified and more compact. The modelling of the observed spectral line energy distribution of CO Jup = 2–6 and [C i] 3P1−3P0 assumes a large velocity gradient scenario, where the analysis is based on four statistical approaches. Since the detected gas and dust emission comes exclusively from only one of the two merging components (the one oriented north–south, NS), we are only able to determine upper limits for the companion. The molecular gas in the NS component in H1429−0028 is found to have a temperature of ∼70 K, a volume density of log (n[cm−3]) ∼ 3.7, to be expanding at ∼10 km s−1 pc−1, and amounts to ${M_{\rm H_2} = 4_{-2}^{+3} \times 10^9\,{\rm M}_\odot }$. The CO to H2 conversion factor is estimated to be $\alpha _{\rm CO} = 0.4_{-0.2}^{+0.3}\,$ M⊙/(K km s−1 pc2). The NS galaxy is expected to have a factor of ≳10× more gas than its companion (${M_{\rm H_2}}\lesssim 3\times 10^8$ M⊙). Nevertheless, the total amount of molecular gas in the system comprises only up to 15 per cent (1σ upper limit) of the total (dynamical) mass.
Transposable Elements Are Important Contributors to Standing Variation in Gene Expression in Capsella Grandiflora
Authors: Uzunović Jasmina , Josephs Emily B , Stinchcombe John R , Wright Stephen I 
Published: April 2019

AbstractTransposable elements (TEs) make up a significant portion of eukaryotic genomes and are important drivers of genome evolution. However, the extent to which TEs affect gene expression variation on a genome-wide scale in comparison with other types of variants is still unclear. We characterized TE insertion polymorphisms and their association with gene expression in 124 whole-genome sequences from a single population of Capsella grandiflora, and contrasted this with the effects of single nucleotide polymorphisms (SNPs). Population frequency of insertions was negatively correlated with distance to genes, as well as density of conserved noncoding elements, suggesting that the negative effects of TEs on gene regulation are important in limiting their abundance. Rare TE variants strongly influence gene expression variation, predominantly through downregulation. In contrast, rare SNPs contribute equally to up- and down-regulation, but have a weaker individual effect than TEs. An expression quantitative trait loci (eQTL) analysis shows that a greater proportion of common TEs are eQTLs as opposed to common SNPs, and a third of the genes with TE eQTLs do not have SNP eQTLs. In contrast with rare TE insertions, common insertions are more likely to increase expression, consistent with recent models of cis-regulatory evolution favoring enhancer alleles. Taken together, these results imply that TEs are a significant contributor to gene expression variation and are individually more likely than rare SNPs to cause extreme changes in gene expression.
NGPhylogeny.fr: new generation phylogenetic services for non-specialists
Authors: Lemoine Frédéric , Correia Damien , Lefort Vincent , Doppelt-Azeroual Olivia , Mareuil Fabien , Cohen-Boulakia Sarah , Gascuel Olivier 
Published: April 2019

AbstractPhylogeny.fr, created in 2008, has been designed to facilitate the execution of phylogenetic workflows, and is nowadays widely used. However, since its development, user needs have evolved, new tools and workflows have been published, and the number of jobs has increased dramatically, thus promoting new practices, which motivated its refactoring. We developed NGPhylogeny.fr to be more flexible in terms of tools and workflows, easily installable, and more scalable. It integrates numerous tools in their latest version (e.g. TNT, FastME, MrBayes, etc.) as well as new ones designed in the last ten years (e.g. PhyML, SMS, FastTree, trimAl, BOOSTER, etc.). These tools cover a large range of usage (sequence searching, multiple sequence alignment, model selection, tree inference and tree drawing) and a large panel of standard methods (distance, parsimony, maximum likelihood and Bayesian). They are integrated in workflows, which have been already configured (‘One click’), can be customized (‘Advanced’), or are built from scratch (‘A la carte’). Workflows are managed and run by an underlying Galaxy workflow system, which makes workflows more scalable in terms of number of jobs and size of data. NGPhylogeny.fr is deployable on any server or personal computer, and is freely accessible at https://ngphylogeny.fr.