bluuebunny/crossref_metadata_2025_split huggingface dataset:
Yanık ünitesi olan tek merkezde geriatrik hastaların yönetimi ve mortaliteyi etkileyen faktörler
Authors: YAVUZ Erkan , KARAGÜLLE Onur Olgaç 
Published: August 2019

Amaç:
Bu non-invaziv retrospektif klinik çalışmada, yanık merkezimizde takip ve
tedavi ettiğimiz geriatrik yaş gurubu hastalarda mortaliteyi etkileyen
faktörleri incelemeyi amaçladık. Materyal ve Metot:
Yanık merkezinde 2016 Ocak ile 2019 Ocak tarihleri arasında yataklı servis ve
yanık yoğun bakım servisinde takip edilen geriatrik yaş grubunda (65 yaş ve
üzeri) 86 hasta dahil edilmiştir. Hasta dosyaları yaş, cinsiyet, yanık
etiyolojisi, yanık yüzdesi [total vücut yüzey alanı (TVYA)], yanık bölgesi,
serviste/yoğun bakımda yatış süresi, eşlik eden (komorbid) hastalıklar, cerrahi
işlemler (Debritman/eskaratomi), yanık derinliği, ASA skoru, greft ve
entübasyon yapılma durumları ve mortalite oranı retrospektif incelendi.
Hastalar serviste takip edilen (hiç
yoğun bakım ihtiyacı olmayanlar) ve yoğun bakım da takip edilen (öncelikle
yoğun bakıma kabul edilen –taburculuk öncesi servise alınanlar) hastalar olmak
üzere iki gruba ayrılarak demografik ve klinik veriler gruplar arasında
karşılaştırıldı. Bulgular:
Charlson komorbidite indeksi (CCI) skorları, serviste yatan hastaların çoğunda
(%58,3) orta şiddette seyrederken yoğun bakımda yatan hastaların çoğunda ise
(%76,3) şiddetli derecede idi. Serviste yatanların çoğunda (%54,2) sıvı yanığı,
yoğun bakımda yatanların yarısında (%50) alev yanığı görüldü. Tüm hastaların
TVYA ortalamaları %16,07 olup, %20 ve üzeri TVYA olan hastaların sayısı yoğun
bakım grubunda servis grubuna kıyasla anlamlı düzeyde fazla idi (P&lt;0,0001).
Anatomik yanık bölgelerine göre servis hastalarının çoğunda (%31,25) ayakta yanık
görülürken yoğun bakım hastalarının çoğunda (%60,53) uyluk ve bacak yanıkları
görüldü. İki grup arasında baş/yüz, üst ve alt ekstiremiteler ve gövde
yanıklarının insidansları açısından anlamlı farklara rastlandı (P&lt;0,05).
Yanık derinliği açısından hasta grupları karşılaştırıldığında 2. Derecede
yanıklar her iki grupta da en sık görülen yanıklardı. Tüm hastaların mortalite
oranı %17,44 ve yoğun bakım hastalarında ise %39,47 idi. Komorbid hastalıklar,
yanık alanın büyüklüğü ve derinliği, ASA skoru, cerrahi müdahaleler ve
entübasyon uygulaması ile mortalite arasında pozitif korelasyonlar saptandı.
Alev ile oluşan veya elde, gövdede, alt ekstremitede ve ayaktaki yanıklarda
artışla birlikte mortalitenin artışı izlendi.

Sonuç:
Yanık hastaları arasında mortalitesi en yüksek oranlarda bulunan geriatric yaş
grubunda gerek eşlik eden hastalıklar gerekse yaşlanmanın vücudun tüm
sistemleri üzerine olan olumsuz etkisi nedeniyle hastaların tedavi ve takibinde
multidisipliner yaklaşım ile mortalite ve morbiditenin azalabileceğini
umuyoruz.
Orta hat kapanma defektlerinde fetuin-a, osteopontin, total antioksidan ve oksidan düzeyleri
Authors: ÇİĞDEM Gulyara , KARABAĞ Hamza , KOYUNCU İsmail 
Published: August 2019

Amaç: Orta Hat kapanma Defekti (OHD) yüksek morbidite ve mortalite ile
ilişkili doğumsal spinal omurgaların birleşme kusurudur. OHD’li olan hastalarda
Fetuin-A, Osteopontin, Total antioksidan ve oksidan seviyeleri bilinmemektedir.
Bu çalışmada bu paramatrelerin OHD’li olan hastalarda düzeyleri ve hastalıkla
olan ilişkisi araştırıldı.Materyal ve
Metot: Çalışmaya, 0-5 yaş grubu
arasında OHD olan hastalar (Çalışma grubu, n=80) ve benzer yaşta sağlıklı
çocuklar (Kontrol grubu, n=85) olmak üzere 165 olgu alındı. OHD olan olgular
Spina Bifida Occulta (Grup I, n=22), Spinal Meningosel veya Miyelomeningosel
(Grup 2, n=26) ve Hidrosefalisi olan (Grup 3, n=31) olmak üzere 3 gruba
ayrıldı. Dağılımların normal olup olmadığı tek yönlü Kolmogorov–Smirnov testi
ile değerlendirildi. Gruplar arası karşılaştırmalarda, ki-kare, student t
testi, Mann-Whitney U testi ve Kruskal-Wallis varyans testleri kullanıldı. Tüm
olgularda Fetuin-A ve Osteopontin sandviç enzim bağlantılı immün sistemi emici
teknolojiye dayanarak ölçüldü, Total Antioksidan Status (TAS) ve Total Oksidan
Status (TOS) spektrofotometrik olarak
ölçüldü. TOS’un TAS’a oranıyla oksidatif
stres indeksi (OSİ) hesaplandı.Bulgular: Hasta ve kontrol grupları arasında TAS düzeyleri benzerdi (p=0.230).
TOS ve OSİ düzeyleri hastalarda, Fetuin-A ve Osteopontin değerleri ise kontrol
grubunda daha yüksek bulundu (hepsi için, p&lt;0.05). TAS düzeyleri hasta
grupları arasında benzer, TOS, Fetuin-A, Osteopontin değerlerinde anlamlı
farklıydı (hepsi için p&lt;0.05). TOS, OSİ ve Fetuin-A düzeyleri grup I den
III’e doğru giderek azalırken, osteopontin düzeyleri grup I’de en yüksek, grup
2’de ise en düşük olarak bulundu.

Sonuç: OHD kapanma defekti, intrauterin dönemde meydana gelir. Embriyogenez
aşamasında, ektodermal tabakadan gelişen nöral dokunun ve mezodermal tabakadan
gelişen ve spinal kordun etrafını saran kemik ve cildin orta hatta yetersiz
kapanması ile sonuçlanan bir malformasyondur. Bu yetersiz kapanma nöral tüpün
herhangi bir yerinde meydana gelebilir. Nöral tüpün histogenezi ve organogenezi
tamamlanması için biyolojik ve kimyasal aktif maddelere ihtiyaç duyarlar (2).
Bu nedenle OHD’li hastaların fizyopatolojisinde, TOS, OSİ, Fetuin-A, Osteopontin
değerlerinin rolü olabileceği düşünülmektedir.
Gejala Buli Secara Fizikal yang Semakin Berleluasa di Sekolah
Authors: Ngo Yew Yung  
Published: August 2019

Konsep buli boleh dilihat kepada elemen-elemen yang terdapat di dalam tingkahlaku buli seperti pembuli, mangsa buli, tujuan dan kesan tingkahlaku buli. Lumrahnya pembuli adalah mereka yang mempunyai sifat sebagai orang lebih kuat, berkuasa dan lebih bermampuan untuk melakukan tingkah laku buli. Kekuatan ini biasanya boleh diperlihatkan sama ada ia adalah secara berseorangan atau berkumpulan. Mereka yang menjadi mangsa kepada pembuli adalah mereka yang lebih lemah dan tidak bermampuan untuk menandingi kekuatan dan kekuasaan si pembuli. Kelemahan ini termasuk lemah dari aspek fizikal dan lain-lain.Oleh kerana itu, maka dilakukan kajian mengenai gejala buli secara fizikal yang semakin berleluasa di sekolah. Objektif kajian ini terdiri dari objektif umum dan objektif khusus. Objektif umum iaitu untuk mengenal pasti isu-isu berkaitan buli di kalangan para pelajar di sekolah. Objektif khusus kajian ini iaitu untuk megenal pasti siapa yang sering membuli dan dibuli, mengetahui adakah pelajar perempuan terlibat dalam perbuatan buli secara fizikal, melihat perbezaan masalah buli fizikal yang dihadapi mengikut peringkat umur, mengenal pasti ciri-ciri pelajar yang sering dibuli di sekolah, mengenal pasti perbezaan umur pelajar yang membuli dan dibuli, mengetahui lokasi yang sering berlaku kegiatan buli fizikal di sekolah, dan mengetahui pengalaman guru tentang gejala buli yang serius menyebabkan campur tangan polis. Metodologi kajian ini iaitu reka bentuk kajian gejala buli secara fizikal yang semakin berleluasa di sekolah adalah berbentuk deskriptif dengan menggunakan keadah temu bual. Antara temu bual yang telah pengkaji buat adalah temu bual semi struktur. Format semi struktur terletak di antara temu bual berstruktur dan tidak berstruktur. Secara keseluruhan, melalui dapatan kajian yang dibentangkan maka dapatlah dirumuskan mengenai perlakuan buli. Perlakuan buli di sekolah menengah sesuatu yang perlu diambil perhatian serius seperti mana di sekolah-sekolah dalam bandar dan luar bandar yang lain.
Validez y confiabilidad del cuestionario de interacción trabajo-familia (swing) en trabajadores de una empresa minera de la libertad, Perú
Authors: Ingunza Lastra Nataly Briggete , Carrasco Muñoz Miguel Alfredo 
Published: August 2019

La presente investigación es de tipo psicométrico, descriptivo y correlacional del cuestionario español «Survey Work-Home Interaction-Nijmegen» (SWING), adaptado por Bernardo Moreno Jiménez para evaluar las relaciones entre el trabajo y la familia. Se estudiaron sus propiedades psicométricas a una muestra de 343 trabajadores, de una empresa minera de la Libertad, Perú. El proceso de validación del cuestionario comprendió en el análisis de la validez de contenido por criterio de jueces a través del coeficiente V de Aiken. La evaluación de la características psicométricas se llevó a cabo en dos fases: en la primera con una muestra piloto para determinar el análisis de reactivos a través del índice de discriminación (la correlación ítem-test). La segunda fase con una muestra objetivo se determinó nuevamente el índice de la discriminación donde se modificó un ítem. Los resultados de los análisis de criterio confirmatorio obtenidos a través del gol estándar (entrevista semiestructuradas), nos indica una correlación media de Pearson con 0,579. El análisis de la fiabilidad de la escala señaló que esta versión adaptada y validada para trabajadores mineros peruanos posee una buena consistencia interna, con valores que se situaron entre 0,825 y 0,892 por área. Se concluye que esta versión posee propiedades psicométricas adecuadas, y se sugieren pautas para el uso de la versión peruana de este cuestionario en futuras investigaciones. También se desarrolló una versión de software del cuestionario; el cual facilita la aplicación y corrección del cuestionario.
The Origin of [C ii] 158 μm Emission toward the H ii Region Complex S235
Authors: Anderson L. D. , Makai Z. , Luisi M. , Andersen M. , Russeil D. , Samal M. R. , Schneider N. , Tremblin P. , Zavagno A. , Kirsanova M. S. , Ossenkopf-Okada V. , Sobolev A. M. 
Published: August 2019

Abstract
Although the

transition of [C ii] at λ ≃ 158

is known to be an excellent tracer of active star formation, we still do not have a complete understanding of where within star formation regions the emission originates. Here, we use SOFIA upGREAT observations of [C ii] emission toward the H ii region complex Sh2-235 (S235) to better understand in detail the origin of [C ii] emission. We complement these data with a fully sampled Green Bank Telescope radio recombination line map tracing the ionized hydrogen gas. About half of the total [C ii] emission associated with S235 is spatially coincident with ionized hydrogen gas, although spectroscopic analysis shows little evidence that this emission is coming from the ionized hydrogen volume. Velocity-integrated [C ii] intensity is strongly correlated with Wide-field Infrared Survey Explorer (WISE) 12

intensity across the entire complex, indicating that both trace ultraviolet radiation fields. The 22

and radio continuum intensities are only correlated with [C ii] intensity in the ionized hydrogen portion of the S235 region and the correlations between the [C ii] and molecular gas tracers are poor across the region. We find similar results for emission averaged over a sample of external galaxies, although the strength of the correlations is weaker. Therefore, although many tracers are correlated with the strength of [C ii] emission, only WISE 12

emission is correlated on small scales of the individual H ii region S235 and also has a decent correlation at the scale of entire range of galaxies. Future studies of a larger sample of Galactic H ii regions would help to determine whether these results are truly representative.
Characterizing the Local Relation between Star Formation Rate and Gas-phase Metallicity in MaNGA Spiral Galaxies
Authors: Sánchez-Menguiano Laura , Almeida Jorge Sánchez , Muñoz-Tuñón Casiana , Sánchez Sebastián F. , Filho Mercedes , Hwang Hsiang-Chih , Drory Niv 
Published: August 2019

Abstract
The role of gas accretion in galaxy evolution is still a matter of debate. The presence of inflows of metal-poor gas that trigger star formation bursts of low metallicity has been proposed as an explanation for the local anticorrelation between star formation rate (SFR) and gas-phase metallicity (Z

g
) found in the literature. In the present study, we show how the anticorrelation is also present as part of a diversified range of behaviors for a sample of more than 700 nearby spiral galaxies from the SDSS-IV MaNGA survey. We have characterized the local relation between SFR and Z

g
after subtracting the azimuthally averaged radial profiles of both quantities. Of the analyzed galaxies, 60% display an SFR–Z

g
anticorrelation, with the remaining 40% showing no correlation (19%) or positive correlation (21%). Applying a random forest machine-learning algorithm, we find that the slope of the correlation is mainly determined by the average gas-phase metallicity of the galaxy. Galaxy mass, g − r colors, stellar age, and mass density seem to play a less significant role. This result is supported by the performed second-order polynomial regression analysis. Thus, the local SFR–Z

g
slope varies with the average metallicity, with the more metal-poor galaxies presenting the lowest slopes (i.e., the strongest SFR–Z

g
anticorrelations), and reversing the relation for more metal-rich systems. Our results suggest that external gas accretion fuels star formation in metal-poor galaxies, whereas in metal-rich systems, the gas comes from previous star formation episodes.
The Sloan Digital Sky Survey Reverberation Mapping Project: Low-ionization Broad-line Widths and Implications for Virial Black Hole Mass Estimation
Authors: Wang Shu , Shen Yue , Jiang Linhua , Horne Keith , Brandt W. N. , Grier C. J. , Ho Luis C. , Homayouni Yasaman , Li Jennifer I-Hsiu , Schneider Donald P. , Trump Jonathan R. 
Published: August 2019

Abstract
The width of the broad emission lines in quasars is commonly characterized by either the FWHM or the square root of the second moment of the line profile (σ
line) and used as an indicator of the virial velocity of the broad-line region (BLR) in the estimation of black hole (BH) mass. We measure FWHM and σ
line for Hα, Hβ, and Mg ii broad lines in both the mean and rms spectra of a large sample of quasars from the Sloan Digital Sky Survey Reverberation Mapping project. We introduce a new quantitative recipe to measure σ
line that is reproducible, is less susceptible to noise and blending in the wings, and scales with the intrinsic width of the line. We compare the four definitions of line width (FWHM and σ
line in mean and rms spectra, respectively) for each of the three broad lines and among different lines. There are strong correlations among different width definitions for each line, providing justification for using the line width measured in single-epoch spectroscopy as a virial velocity indicator. There are also strong correlations among different lines, suggesting that alternative lines to Hβ can be used to estimate virial BH masses. We further investigate the correlations between virial BH masses using different line width definitions and the stellar velocity dispersion of the host galaxies and the dependence of line shape (characterized by the ratio FWHM/σ
line) on physical properties of the quasar. Our results provide further evidence that FWHM is more sensitive to the orientation of a flattened BLR geometry than σ
line, but the overall comparison between the virial BH mass and host stellar velocity dispersion does not provide conclusive evidence that one particular width definition is significantly better than the others.
BATF-Interacting Proteins Dictate Specificity in Th Subset Activity
Authors: Fu Yongyao , Koh Byunghee , Kuwahara Makoto , Ulrich Benjamin J. , Kharwadkar Rakshin , Yamashita Masakatsu , Kaplan Mark H. 
Published: August 2019

Abstract
The basic leucine zipper (bZIP) transcription factor BATF is expressed in multiple Th subsets and cooperates with other factors to regulate gene transcription. BATF activates lineage-specific cytokines in Th subsets, activating IL-9 in Th9 cells and IL-17 in Th17 cells, but not IL-9 or IL-17 in the reciprocal subset. The mechanism for this restricted activity is unclear. In this report, we define BATF binding partners that contribute to Th subset–specific functions. Although BATF and IRF4 are expressed in greater amounts in Th9 than Th17, increased expression of both factors is not sufficient to induce IL-9 in Th17 cells. BATF also requires heterodimer formation with Jun family members to bind DNA and induce gene expression. Using primary mouse T cell culture, we observed that JunB and c-Jun, but not JunD, promote IL-9 production in Th9 cells. Ectopic expression of BATF with either JunB or c-Jun generates modest, but significant, increases in IL-9 production in Th17 cells, suggesting that the low expression of Jun family members is one factor limiting the ability of BATF to induce IL-9 in Th17 cells. We further identified that Bach2 positively regulates IL-9 production by directly binding to the Il9 gene and by increasing transcription factor expression in Th9 cells. Strikingly, cotransduction of Bach2 and BATF significantly induces IL-9 production in both Th9 and Th17 cells. Taken together, our results reveal that JunB, c-Jun, and Bach2 cooperate with BATF to contribute to the specificity of BATF-dependent cytokine induction in Th subsets.
The human endosalpinx: anatomical three-dimensional study and reconstruction using confocal microtomography
Authors: Castro Pedro Teixeira , Aranda Osvaldo Luiz , Matos Ana Paula Pinho , Marchiori Edson , Araújo Luiz Felipe Bittencourt de , Alves Haimon Diniz Lopes , Machado Alessandra Silveira , Lopes Ricardo Tadeu , Werner Heron , Júnior Edward Araujo 
Published: August 2019

PurposeTo evaluate in three dimensions (3D) the human endosalpinx and reconstruct its surface along its different anatomical segments, without the injection or insertion of luminal contrasts, using confocal microtomography (micro-CT).Material and methods15 fallopian tubes (FT) from 14 women in reproductive age from procedures for benign disease or sterilization were selected. The specimens were fixed in formalin and stained with Lugol solution. Micro-CT studies were conducted on the specimens using protocols adapted from biological studies, to acquire images to reconstruct in 3D the endosalpinx surface.ResultsFrom these specimens, 6 presented the intra-mural segment, 14 presented the isthmus and 15 presented the ampulla and fimbria segment of the FT. The specimen presented tissue definition, and contrast sufficient for FT endosalpinx morphological analysis and lumen definition. The intramural portion presented initially a mucosal projection toward the lumen, bending on its own axis, and increased numbers of projections towards the isthmic portion, where the projections become longer more numerous. The endosalpinx becomes more tortuous, the lumen diameter increases and the mucosal projections become more bulky in the ampullary portion, with the projections less present on the antimesenteric side. The infundibular portion is marked with the organized and predictable endosalpinx, the abdominal ostium is cleared demonstrated, with the reduction of the endosalpinx volume. The fimbria demonstrated a small relation between fringes and intratubal endosalpinx.ConclusionsMicroscopic anatomy of different segments of the human FT mucosa can be analyzed and reconstructed in 3D with histological correlation using micro-CT.
Zircon Petrochronology of the Meghri-Ordubad Pluton, Lesser Caucasus: Fingerprinting Igneous Processes and Implications for the Exploration of Porphyry Cu-Mo Deposits
Authors: Rezeau Hervé , Moritz Robert , Wotzlaw Jörn-Frederik , Hovakimyan Samvel , Tayan Rodrik 
Published: August 2019

AbstractThe trace element composition of zircon, especially in tandem with U-Pb geochronology, has become a powerful tool for tracing magmatic processes associated with the formation of porphyry copper deposits. However, the use of the redox-sensitive Eu and Ce anomalies as a potential mineral exploration proxy is controversial. This study presents a comprehensive, temporally constrained data set of zircon trace element compositions (n = 645) for three compositionally distinct magmatic series identified in the Meghri-Ordubad pluton, southernmost Lesser Caucasus. The 30 million years of Cenozoic magmatism in the Meghri-Ordubad pluton are associated with several ore-forming pulses leading to the formation of porphyry copper deposits and epithermal-style mineralization. Our zircon geochemical data constrain the thermal and chemical evolution of this complex intrusive suite and allow an evaluation of the usefulness of zircon as a mineral exploration proxy for porphyry copper deposits. Our results combined with Rayleigh fractionation modeling indicate that the trace element composition of zircon (Th/U, Hf, Ti, YbN/DyN, Eu anomalies) is influenced by the composition and the water concentration of the parental magma, as well as by co-crystallizing titanite and apatite. In contrast, the variations of Ce anomalies remain difficult to explain by magmatic processes and could rather be ascribed to relative fluctuations of the redox conditions. In the Meghri-Ordubad pluton, we do not observe any systematic patterns between the trace element composition in zircons and the different ore-forming pulses. This questions the reliability of using the trace element composition in zircon as an exploration mineral proxy, and it rather emphasizes that a good knowledge of the entire magmatic evolution of a metallogenic province is required.
Ring spring dampers
Authors: Bishay-Girges Nagui W. , Carr Athol J. 
Published: August 2019

When a structure is excited by an earthquake ground motion the input energy may be reduced by inelastic action or by supplemental damping devices. If the seismic energy dissipation can be achieved by means of separate non-load bearing supplementary damping systems, the structure itself can remain elastic providing a continuing serviceability following the design level earthquake.
This paper illustrates the advantages of using added, or supplemental, damping in structures. The control system consists of passive friction dampers installed in the ground floor of the structure using tendons to transmit the damper forces to the other parts of the structure. The damping forces generated by the dampers are transferred to the structure by the tendons and horizontal links that oppose the inertial loads applied to the structure by the earthquake excitation. The dampers are ring spring friction devices consisting of inner and outer ring elements assembled to a form a spring interface. A four storey-two bay steel frame was used in the study.