bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two Distinct Types of Extratropical Circulation Anomalies Associated with Cold Surges over the South China Sea
Authors: Pang Bo , Lu Riyu 
Published: May 2019

Abstract
This study investigated the extratropical circulation anomalies responsible for cold surges over the South China Sea in winter. The surge events were identified by the intensity of northerly winds over 110°–117.5°E along 15°N at 925 hPa. Two distinct patterns of sea level pressure (SLP) anomalies in East Asia were found to have a crucial role in inducing cold surges over the South China Sea. Accordingly, the cold surge events were classified into two types. The first type of cold surge is characterized by a pair of SLP anomalies with positive and negative ones centered over China and Japan, respectively, whereas the second type of cold surge is characterized by widespread and persistent positive SLP anomalies over East Asia. Furthermore, the first type of cold surge is accompanied by a deepened East Asian trough and precursory Rossby wave trains across the Eurasian continent in the mid- and upper troposphere, but the latter is not. Prior to both types of the cold surges, the Siberian high is significantly intensified. However, diagnosis of the SLP tendency indicates that the intensification is related to different physical processes. In the first type of cold surge, the Rossby wave trains favor negative vorticity advection and cold advection, inducing intensification of the Siberian high. By contrast, in the second type of cold surge, vorticity advection can be ignored due to the lack of Rossby wave trains, and only the lower-tropospheric cold advection induced by anomalous northerly winds, resulting from the anomalous Siberian high, contributes to the further intensification of the Siberian high.
Tropical Cyclone–Related Precipitation over the Northwest Tropical Pacific in Met Office Global Operational Forecasts
Authors: Peatman Simon C. , Klingaman Nicholas P. , Hodges Kevin I. 
Published: May 2019

AbstractThe tropical west Pacific Ocean and the Philippines are often affected by tropical cyclones (TCs), with threats to human life and of severe economic damage. The performance of the Met Office global operational forecasts at predicting TC-related precipitation is examined between 2006 and 2017, the first time total TC rainfall has been analyzed in a long-term forecast dataset. All precipitation falling within 5° of a TC track point is assumed to be part of the TC rainbands. Forecasts are verified against TC tracks from the JRA-55 reanalysis and precipitation from TRMM 3B42. In composites from the forecasts, the total precipitation (TC and non-TC) is too high and the TC-related precipitation is too low, over both ocean and the Philippines. These biases exist all year-round and generally worsen with lead time, but have improved in recent years with upgrades to the forecasting system. Biases in TC-related precipitation in the Philippines are attributable mainly to TC lifetime being too short over land and ocean and (over land) possibly to individual TCs producing too little rain. There are considerable biases in predicted large-scale conditions related to TC intensification, particularly too little lower-troposphere relative humidity and too strong vertical wind shear. The shear appears to have little impact on the amount of TC precipitation, but dry biases in humidity are consistent with dry biases in TC rainfall. The forecast system accurately reproduces the impact of the MJO on TC precipitation, relative to the forecasts’ own climatology, potentially providing the opportunity for predictability out to several weeks.
Stroke patients’ and non-professional coaches’ experiences with home-based constraint-induced movement therapy: a qualitative study
Authors: Stark Anne , Färber Christine , Tetzlaff Britta , Scherer Martin , Barzel Anne 
Published: May 2019

Objective: To investigate the experiences of chronic stroke patients and non-professional coaches with home-based constraint-induced movement therapy (homeCIMT). Design: Qualitative study embedded within a cluster randomized controlled trial investigating the efficacy of homeCIMT to improve the use of the affected arm in daily activities. Setting: Patients’ home environment. Participants: 13 stroke patients and 9 non-professional coaches’ alias family members who had completed the four-week homeCIMT programme in the context of the HOMECIMT trial. Interventions: Semi-structured interviews; qualitative data were analysed using the methodology of the hermeneutic phenomenological data analysis. Results: We identified six themes in the qualitative analysis describing the experiences of patients and non-professional coaches with homeCIMT: (1) homeCIMT can be integrated into everyday life with varying degrees of success; (2) training together may produce positive experiences as well as strain; (3) self-perceived improvements during and following homeCIMT; (4) using the affected arm in everyday life is challenging; (5) subjective evaluation of and experiences with homeCIMT-specific exercises; and (6) impact of professional therapists’ guidance and motivation during homeCIMT. Statements regarding theme five and six were only provided by patients, whereas the other themes contain both, the experiences of stroke patients and non-professional coaches. Conclusion: Patients’ and non-professional coaches’ narratives offer a detailed insight into the manifold experiences with the practical implementation of homeCIMT that may help improve implementing the homeCIMT programme and similar approaches involving increased training duration and intensity and/or involvement of family members.
Performance and Return to Sport After Open Reduction and Internal Fixation of the Olecranon in Professional Baseball Players
Authors: Erickson Brandon J. , Chalmers Peter N. , D’Angelo John , Ma Kevin , Ahmad Christopher S. , Romeo Anthony A. 
Published: May 2019

Background: The results of open reduction and internal fixation (ORIF) of stress reactions and fractures of the olecranon among professional baseball players with regard to return to sport (RTS) are unknown. Purpose/Hypothesis: To determine the RTS rate and performance of professional baseball players after ORIF of acute, displaced olecranon fractures and olecranon stress fractures and to compare the RTS rate and performance with that of matched controls. The authors hypothesized that there is a high rate of RTS among professional baseball players after ORIF of acute, displaced olecranon fractures and olecranon stress fractures with no significant difference in rate of RTS or performance between cases and controls. Study Design: Cohort study; Level of evidence, 3. Methods: All professional baseball players who underwent ORIF of the olecranon between 2010 and 2016 were included. Demographic and performance data (before and after surgery) for each player were recorded. Performance metrics were then compared between cases and a group of matched controls. Results: Overall, 52 professional baseball players (mean ± SD age, 22.6 ± 3.6 years) underwent ORIF of an olecranon fracture. The majority of players sustained a primary olecranon stress fracture (73%) that was fixed with 1 screw (60%), with an overall RTS rate of 67.5%. No difference in RTS rate existed between matched controls and the cases. No significant difference existed between the primary pre- and postoperative performance metrics (ie, change in performance) for pitchers who underwent ORIF of an acute, displaced olecranon fracture or ORIF of a primary olecranon stress fracture. No significant difference existed between pitchers who underwent ORIF of a primary olecranon stress fracture and matched controls in any of the primary performance metrics. Three cases and 2 controls underwent ulnar collateral ligament reconstruction later in their careers after olecranon ORIF. Conclusion: Professional baseball players who undergo ORIF of an olecranon fracture (acute, displaced, or stress) have an RTS rate of 67.5% (57.6% to the same or higher level), which is no different from natural attrition among matched controls. No decline in performance metrics was seen among players who were able to RTS when compared with their preoperative performance or the performance of matched controls.
Factors Influencing Patients’ Experiences of Pain Management in the Emergency Department
Authors: Shoqirat Noordeen , Mahasneh Deema , Khresheh Reham , Singh Charleen , Al-Momani Muwafaq M. , Al-Kalaldeh Mahmoud 
Published: May 2019

Background Despite management of acute pain, concerns regarding pain are still prevalent in the emergency department (ED). Purpose This study aimed to explore the factors influencing patients’ pain management in a Jordanian ED. Method Fifteen semistructured interviews (N = 15) with purposively selected patients in the ED. Results The thematic analysis uncovered two related themes. The first theme described the stage of “being on ED bed” which encapsulates two subthemes: “bad pain means, bad diagnosis” and “smiley faces versus grumpy faces.” The second theme referred to as “being discharged” including two subthemes, namely, “praying for not paying” and “being grateful to God.” The lack of money to pay for pain management was equally as stressful as pain itself. Patients’ narratives suggest that nursing pain management is a critical time, extending beyond medical management to encompass communication and spirituality. Conclusions The factors influencing the patients’ experience of pain management extend beyond addressing the source of the pain. Consequently, effective communication coupled with respecting patients’ spirituality and socioeconomic concerns is essential to pain management. To enhance patients’ experience of pain management, the ED system should shift toward a patient-centric model.
Adherence to a topical moisturizing preparation for regorafenib-related hand-foot skin reaction
Authors: Sato Junya , Ishikawa Hiroshi , Hamauchi Satoshi , Yamawaki Yuki , Mori Keita , Kiyohara Yoshio , Yoshikawa Shusuke , Yamazaki Kentaro , Yasui Hirofumi , Shino Michihiro 
Published: May 2019

Objective Application of topical moisturizing preparations is important for the prevention and palliation of hand-foot skin reaction induced by multi-kinase inhibitor. Application adherence of topical moisturizing preparations in clinical practice has rarely been reported. This study investigated the factors affecting adherence to the application of topical moisturizing preparations in patients administered regorafenib. Methods The subjects were patients administered regorafenib ( n = 118). Consumption of a urea-based moisturizing ointment, hand-foot skin reaction grade (CTC-AE ver 3.0), treatment duration, and dose of regorafenib, factors that might affect the onset of symptoms and adherence, including age, sex, presence of a key person, working status, performance status, past use of capecitabine or epidermal growth factor receptor antibodies, and relative dose intensity were retrospectively investigated. The adherence to the topical moisturizing ointment (<21 g per week) was judged as poor. The data were analyzed by logistic regression analysis. Results Working status was associated with poor adherence, showing a positive correlation (odds ratio; 3.024, p = 0.023). In contrast, symptom grade of hand-foot skin reaction and regorafenib relative dose intensity showed negative correlation with poor adherence (odds ratio; 0.971, p = 0.012, and 0.485, p < 0.001, respectively). Conclusions The results suggest that adherence decreases in patients with working. The relative dose intensity of regorafenib decreased when adherence to topical moisturizing ointments decreased. Severe hand-foot skin reaction could be associated with adherence. Patients consciously might not apply the ointment when hand-foot skin reaction did not become severe. It will be problematic for medical personnel to motivate patients for improving adherence to the use of moisturizing ointments.
Complete Coronary Revascularization via Left Anterior Thoracotomy
Authors: Babliak Oleksandr , Demianenko Volodymyr , Melnyk Yevhenii , Revenko Katerina , Pidgayna Liliya , Stohov Oleksii 
Published: May 2019

Objective Our aim was to develop the minimally invasive coronary artery bypass grafting (CABG) technique, which is equally effective and safe compared with conventional coronary grafting technique, is reproducible, and can be applied in the vast majority of patients with isolated coronary artery disease. Methods From July 2017 to November 2018 a total of 170 nonselected consecutive patients underwent minimally invasive on-pump multivessel CABG through the left anterior minithoracotomy in the fourth intercostal space using a Chitwood clamp and blood cardioplegia. We named this technique total coronary revascularization via left anterior thoracotomy. The mean number of grafts was 3.1 ± 0.7. Left internal mammary artery was used in 159 (93.5%) patients, right internal mammary artery in 4 (2.4%) patients, radial artery in 25 (14.7%) patients, and veins in 148 (87%) patients. Results We had no mortality, no postoperative myocardial infarcts, and no conversion to sternotomy. There were 2 postoperative strokes without residual neurological deficit and 2 revisions for postoperative bleeding. The total operation time was 258.8 ± 43.9 minutes, cardiopulmonary bypass time 135.8 ± 26.6 minutes, and aortic cross-clamp time 71.2 ± 19.4 minutes. The mean intensive care stay was 2.1 ± 0.56 days and mean total hospital stay 6.3 ± 1.3 days. Conclusions Complete coronary revascularization could be routinely performed using the above-mentioned technique. No patient selection, based on number of grafts, quality and location of coronary vessels, left ventricle function, age, gender, or body mass index, is required.
Circular RNA ABCB10 promotes tumor progression and correlates with pejorative prognosis in clear cell renal cell carcinoma
Authors: Huang Yunfang , Zhang Yun , Jia Lin , Liu Changxuan , Xu Fang 
Published: May 2019

Objective: Our study aimed to evaluate the effect of circular RNA ABCB10 (circ-ABCB10) on proliferation and apoptosis of clear cell renal cell carcinoma (ccRCC) cells, and its prognostic value in patients with ccRCC. Methods: Circ-ABCB10 expression in five ccRCC cell lines and normal kidney epithelial cell line was measured by quantitative polymerase chain reaction (qPCR). Empty overexpression, circ-ABCB10 overexpression, empty shRNA, and circ-ABCB10 shRNA plasmids were transfected into A498 cells as negative control for circ-ABCB10 over expression {NC (+)}, Circ-ABCB10(+), negative control (−){NC(−)}, and Circ-ABCB10(−) groups, then cell proliferation and apoptosis were evaluated by Cell Counting Kit-8 and annexin V/propidium iodide. Meanwhile, apoptotic markers were measured by western blot. Subsequently, circ-ABCB10 expression in tumor tissues and paired adjacent tissues from 120 ccRCC patients was measured by qPCR. Results: Circ-ABCB10 expression was elevated in all the ccRCC cell lines compared with the normal kidney cells line. A498 cell proliferation was enhanced in the Circ-ABCB10(+) group compared with the NC(+) group, while it was inhibited in the Circ-ABCB10(−) group compared with the NC (−) group; and A498 cell apoptosis was repressed in the Circ-ABCB10(+) group than the NC(+) group, but was promoted in the Circ-ABCB10(−) group compared with the NC(−) group. In addition, circ-ABCB10 was up-regulated in tumor tissues compared with paired adjacent tissues, and its high expression correlated with the advanced pathological grade and the tumor node metastasis stage as well as independently predicting worse overall survival in ccRCC patients. Conclusion: Circ-ABCB10 promotes tumor progression and correlates with pejorative prognosis in ccRCC.
Cancer and breast cancer awareness interventions in an intellectual disability context: A review of the literature
Authors: Walsh S , O’Mahony M , Lehane E , Farrell D , Taggart L , Kelly L , Sahm L , Byrne A , Corrigan M , Caples M , Martin AM , Tabirca S , Corrigan MA , Hegarty J 
Published: May 2019

Background: Women with an intellectual disability (ID) have a similar risk of developing breast cancer as women in the general population yet present with later stage breast cancers, which have poorer outcomes. Aim: To identify whether there is a need to develop a breast cancer awareness intervention for women with an ID. Methods: Interventions aimed at increasing cancer awareness and breast cancer awareness for people with an ID were identified and critically appraised. Results: Five interventions to increase cancer awareness or breast cancer awareness in people with an ID were identified. Conclusion: The review highlighted the paucity of theoretically underpinned breast cancer awareness interventions specifically aimed at women with an ID. Facilitating breast cancer awareness for women with an ID could potentially lead to earlier presentation of potential symptoms of breast cancer, earlier treatment, better prognosis and ultimately, improved survival. This article establishes that there is a need for an intervention underpinned by theory to increase breast cancer awareness in women with an ID.
Gender disparities in patient education provided during patient visits with a diagnosis of coronary heart disease
Authors: Hilleary Rebecca S , Jabusch Sarah M , Zheng Becky , Jiroutek Michael R , Carter Charles A 
Published: May 2019

Background: Cardiovascular disease is the leading cause of death in females in the United States. Prior studies have reported that females receive less patient education and preventive counseling for cardiovascular disease as compared with males. The American Heart Association and others have embarked on several initiatives over the last 20 years to narrow this disparity of care. The primary objective of this study was to determine whether a gender disparity remains in the provision of patient education among patients diagnosed with coronary heart disease, a form of cardiovascular disease. The secondary objective was to determine whether there is an association between the provision of patient education and sociodemographic variables and risk factors. Methods: This was a retrospective, cross-sectional, observational study of adults (⩾18 years) diagnosed with coronary heart disease who participated in National Ambulatory Medical Care Survey between the years 2005 and 2014, inclusive. Chi-square tests of independence were performed to address the primary objective. A multivariable logistic regression model was constructed to assess the association between gender and provision of patient education while adjusting for sociodemographic variables and risk factors of interest. Results: A total raw survey sample size of 17,332 patient visits meeting the study inclusion/exclusion criteria was utilized. Patients were predominately white, male, non-Hispanic, and ⩾75 years of age. Females had 0.86 times the odds of receiving patient education compared with males (95% confidence interval = 0.78–0.95, p = 0.0024). After adjusting for covariates of interest, gender remained statistically significant in the multivariable logistic model. In addition, the variables “other payer” (vs private insurance), tobacco use, primary care physician type, obesity, hyperlipidemia, and hypertension were found to be statistically significantly associated with the provision of patient education (p < 0.05) in the multivariable analysis. Conclusion: In the data analyzed, gender disparities exist, as evidenced by a greater proportion of males receiving patient education than females, among coronary heart disease patients during visits seeking medical care. The acceptability of these findings in terms of overall patient management and treatment goals requires further evaluation.
A literature review of interventions to reduce stress in doctors
Authors: Locke Rachel , Lees Amanda 
Published: May 2019

Aim: Stress is prevalent among doctors, and interventions are offered, often as part of their continuing professional development, to help doctors learn in the workplace about the recognition, prevention and management of the harmful effects of stress. The aim of this review was to examine existing research to ascertain the features of successful educational interventions with practising doctors and any factors that may affect outcomes. Methods: We searched key databases for papers published between 1990 and 2017 on the themes of stress that included an education-based intervention and practising doctors. Using an inclusive approach to the review, a broad evaluation was made of the primary research using both quantitative and/or qualitative evidence where the study reported a positive outcome in terms of stress management. Results: Review criteria were met in 31 studies of 1,356 originally retrieved. Three broad categories of interventions emerged from the coding process: mindfulness-type ( n = 12), coping and solutions focused (CSF) ( n = 12) and reflective groups ( n = 7). There is evidence that these interventions can be successful to help doctors deal with stress. Based on the results from this review, an original guide is advanced to help educators choose an educational intervention. Conclusion: Although evidence for some interventions may be ‘hierarchically stronger’, it is misleading to assume that interventions can be imported as successfully into any context. Factors such as medical specialty and health care systems may affect which intervention can be used. The guide offers an evidence base on which further research can be built.
Mock-Ups: Using Experiential Simulation Models in the Healthcare Design Process
Authors: Durham Joyce , Kenyon Ann 
Published: May 2019

Purpose: The purpose of this article was to explore how different types of mock-ups are being used in the healthcare design process and present a methodology framework for the process. Background: Historically, physical mock-ups have been used in healthcare design primarily to test construction techniques. Although this historic use of mock-ups assisted the design team in decision-making, newer forms of mock-ups have evolved that expand the input provided into decision-making. These newer techniques, rapid prototyping, early build-out, virtual reality, and enhancements to the traditional physical mock-up focus more on challenging the functionality of the space, testing new operational concepts, and increasing user input. Method: This methodology article utilized five case studies in which different types and combinations of mock-ups were used in the design process and then, the methodology compares the realism, immersion, and testability of each mock-up technique. Results: For each mock-up type, the case studies described the purpose of the technique, the advantages and disadvantages, the most appropriate phase for its use in the design process, the estimated cost, and the process logistics. These components are compared to assist in developing a methodology for a variety of design situations. Conclusions: The findings related to different mock-up techniques are a valuable tool for healthcare design teams to use in selecting the most appropriate mock-up technique and the proposed methodology will assist in executing the mock-up process.