bluuebunny/crossref_metadata_2025_split huggingface dataset:
PRP vs Hialuronic Acid for the Treatment of Knee Osteoarthritis
Authors: Alfaro Luis Antonio Goytia 
Published: December 2018

Objectives: Knee osteoarthritis is a pathology of great prevalence and increase the cost to society due to loss of work, early retirement, and arthroplasty. In recent years, new non-surgical treatment alternatives have emerged based on intra-articular infiltrations with the aim of temporarily relieving symptoms and postponing definitive prosthetic treatment. The purpose of this work is to evaluate the effectiveness of intrarticular inyections with high molecular weight hyaluronic acid (HMWHA), low molecular weight hyaluronic acid (LMWHA) and platelet rich plasma (PRP). Methods: Forty one patients were taken into account in this work, five infiltrations with LMWHA were applied to sixteen patients, a single infiltration of HMWHA was applied to twelve patients and thirteen patients were treated with three PRP infiltrations. According to Kellgreen Lawrence’s classification (KL), twenty three patients were grade II and eighteen patients were grade III. Patients were evaluated according to the WOMAC and KOOS Scales prior to treatment and at four months. Patients who had any surgical, infiltrative treatment or non surgical treatment of the knee and those who used any other adjuvant treatment after the infiltration were excluded from the sample. Results: Patients were evaluated using the WOMAC and KOOS scales prior to infiltration and four months after treatment. Groups treated with HMWHA and those treated with PRP had the best results on both scales: Patients with grade II and III KL classification treated with PRP improved an average of 25 points on both scales. Likewise, those treated with HMWHA improved an average of 30 points and 25 points respectively. Finally, those who received LMWHA obtained an improvement of 21 points and 17 points respectively, which translates into a statistically significant result in favor of HMWHA and PRP compared to LMWHA, P < .05 Conclusion: These treatments are valid options for the relief of symptoms of degenerative knee osteoarthritis. The AH being the only one approved by the FDA, and the PRP through more and more serious studies, is proving its effectiveness in the treatment of this pathology. According to the results obtained, it is HMWHA that seems to be more effective in grade II osteoarthritis, in those patients with grade III osteoarthritis the results were similar for both PRP and HMWHA. On the other hand, relief was less in patients treated with LMWHA regardless of their degree of osteoarthritis.
Surgical Technique for fixation of posterior root tears of the lateral meniscus and anterior cruciate ligament ruptures in acute lesions: Short-term clinical outcome
Authors: Jaramillo Germán A. , Arias Rubén D. , Arrubla Esteban , Valencia Natalia 
Published: December 2018

Background: Injuries of posterior lateral meniscus root (PLMR) are related to an acute trauma mechanism, which is commonly associated with anterior cruciate ligament (ACL) rupture. Many biomechanical studies have exposed the importance of the integrity of PLMR. There are several surgical techniques for its treatment, but is still controversial about which is the most appropriate, especially for combined injuries. Objective: To describe the clinical outcomes of patients with a surgical treatment of PLMR tear combined with ACL rupture Methods: Prospective case series. With patients who undergone repair of PLMR tears with ACL rupture, from 2016 to 2017 in a specialized hospital in Medellín city. Clinical evaluation it was determinate with Lysholm and IKDC (International Knee Documentation Committee) scores, before and one year after the surgical procedure. The paired sample t-test was applied to compare the results of the scores. Results: Six patients with acute lesion of PLMR tear combined with ACL rupture received treatment with a variation in the transtibial fixation of the PLMR surgical technique. Statistically significant differences were found when comparing the two scores before and after surgery (p=<0.05). In addition, no additional surgical interventions were performed in the follow-up time. Conclusion: The combined surgical treatment of PLMR and ACL injuries can be performed safely. This surgical technique provided an improvement in function, pain and activity level, which may help to delay the progression of osteoarthritis of the knee.
ACL partial tears: Is it possible to define which bundle is compromised using magnetic resonance?
Authors: Stagnaro Joaquín , Rasumoff Alejandro , Yacuzzi Carlos H. , Zicaro Juan Pablo , Paz Matías Costa 
Published: December 2018

Objective: Anterior Cruciate Ligament (ACL) tears are diagnosed through a clinical examination and imaging confirmation. Magnetic Resonance Imaging (MRI) is the diagnostic image method of choice; however the sensitivity is variable for the different kind of partial injuries. The objective of this study is to evaluate the effectiveness of the MRI in the diagnosis of clinically unstable partial ACL tears that already underwent surgical treatment and define which bundle was compromised. Methods: A retrospective review of the preoperative MRI of 40 patients who were surgically operated because of ACL tears was executed. In all cases, arthroscopic findings defined one bundle was intact. All MRI were reviewed by a single osteo-articular specialist staff of the Image Department. All injuries were classified according to which bundle was involved (anteromedial (AM) or posterolateral (PL)). Results were compared with the surgical findings. Results: Concordance between MRI and arthroscopic findings was 42.5% (17/40 patients). If we analyze AM and PL tears separately we found that the concordance was 51.5% for AM bundle tears (17/33) and 0% for PL bundle tears (0/7). Conclusion: Definitive diagnosis and surgical indication for ACL tears requires both, clinical examination and image diagnosis. Over 65% of partial tears are misdiagnosed by MRI only.
A novel technique for bone marrow concentrate aspiration from the intercondylar notch during arthroscopic ACL reconstruction
Authors: Figueroa David , Bernal Nazira , Arellano Sergio , Donoso Rodrigo , Figueroa Francisco , Vaisman Alex , Calvo Rafael 
Published: December 2018

Objectives: Anterior cruciate ligament Reconstruction (ACL-R) is a frequent surgery with a failure rate of 8-10%, being a cause the lack of integration of the graft. Methods of biological augmentation have been developed, such as the extraction of human mesenchymal cells by aspiration of BMC. Objective: describe and demonstrate the safety of a new arthroscopic technique of BMC aspiration from the femoral intercondylar notch. Methods: Prospective non-randomized clinical study of 45 consecutive patients undergoing anatomic ACL-R with hamstring autograft. Patients with Multiligamentary injuries or revision ACL surgery were excluded. Control group was composed by 19 patients that underwent isolated ACL-R. Intervention group was composed by 29 patients who underwent ACL-R, BMC aspiration and subsequent instillation of the BMC. Variables assessed to compare both groups were: Demographics, Surgical Time and Complications (hemarthrosis, rate of infection and risk of fracture). BMC Aspiration Technique was performed before tunnel drilling and shutting-off the water pump. Through the medial portal, the 14-gauge trocar/needle aspiration device was introduced and positioned into the upper and central region of the intercondylar notch. With a clockwise-like twisting motion, the trocar was used to pierce the cortex 25 mm into the distal femur, obtaining 60 ml of BM which was processed with the Angel system (ArthrexR). Finally, under dry arthroscopic vision, the BMC was instilled in both bone tunnels and into the graft. Statistical analysis was performed in stata 11, considering a statistical significance of 5%. Results: No demographic differences were reported. The surgical time of the control group was 50.57 min (SD 8.44) and intervention group 65.69 min (SD 10.98) (p <0.011). 0% of complications associated with the procedure were reported. Conclusion: The aspiration of BMC through the femoral intercondylar notch during the arthroscopic ACL-R, is a safe, reproducible technique without associated complications, however, it significantly increases the surgical time.
A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models
Authors: Hamilton Noémie , Sabroe Ian , Renshaw Stephen A. 
Published: December 2018

Haematopoietic stem cell (HSC) transplantation is a critical therapy for haematopoietic malignancies and immune disorders. Incomplete or delayed engraftment of HSCs in the host results in increased risk of infection and morbidity. The mechanisms of HSC engraftment are poorly understood and understanding these processes will increase transplantation success on many levels. Current animal models are immunocompromised 'humanised' mice transplanted with human HSCs. Harmful procedures include genetic manipulations and irradiation to ablate the mouse immune system, and opaque mouse tissues make visualisation of the early steps of HSC engraftment impossible. There is a need for new models to offer alternatives to humanised mice in the study of HSC transplantation. Here we described a detailed method for transplantation of human HSCs into zebrafish, before the onset of adaptive immunity. Human HSCs were purified from whole blood by enrichment of the CD34 cell population using a positive magnetic selection and further purified using an anti-CD34 antibody and cell sorting. Sorted CD34 cells were transplanted into the blood stream of 52 hour old zebrafish larvae. Human HSCs home into the zebrafish haematopoietic niche, where they engage with endothelial cells and undergo cell division. Our model offers the opportunities to image in vivo human HSC engraftment in a transparent organism, without the myeloablative strategies used in mice, and provides a unique system to understand the dynamic process of engraftment and replace current murine models. This technique can be applied to current engraftment protocols to validate the viability and efficiency of cryofrozen HSC grafts. This humanised zebrafish model will be instrumental to develop the 3Rs values in stem cell transplantation research and our detailed protocol will increase the chances of uptake of this zebrafish model by the mouse community.
Recurrent internal hip rotation gait in cerebral palsy: Report of two patients
Authors: O'Sullivan Rory , Kiernan Damien 
Published: December 2018

Internal hip rotation in cerebral palsy (CP) is typically treated with a femoral derotation osteotomy. This has been shown to be largely a successful procedure but recurrence rates up to 41% have been reported. Reported risk factors include younger age, reduced hip joint impulse and ankle plantar-flexion. We report on two patients with bilateral CP demonstrating recurrent unilateral internal hip rotation despite surgical intervention(s). Both demonstrate a number of the reported risk factors for recurrence. In addition, this case report specifically compared gait kinematic patterns pre and post recurrence. On comparing both patient’s hip rotation and ankle dorsi/plantarflexion kinematics they are seen to be almost identical both pre-operatively and post-operatively. Both patients appear to revert to approximately 30o of internal hip rotation which has been shown to maximise hip abductor function. Therefore, surgical derotation in isolation is unlikely to be successful in this group and we suggest that this hip and ankle pattern may help predict recurrence in unilateral internal hip rotation.
High malaria transmission sustained by Anopheles gambiae s.l. occurring both indoors and outdoors in the city of Yaoundé, Cameroon
Authors: Doumbe-Belisse Patricia , Ngadjeu Carmene Sandra , Sonhafouo-Chiana Nadege , Talipouo Abdou , Djamouko-Djonkam Landre , Kopya Edmond , Bamou Roland , Toto Jean Claude , Mounchili Souleyman , Tabue Raymond , Awono-Ambene Parfait , Wondji Charles Sinclair , Njiokou Flobert , Antonio-Nkondjio Christophe 
Published: December 2018

Background:Malaria remains a major public health problem in Cameroon; however, despite reports on the adaptation of anopheline species to urban habitats, there is still not enough information on malaria transmission pattern in urban settings. In the frame of a larval control trial in the city of Yaoundé, we conducted baseline surveys to assess malaria transmission dynamics in this city.Methods:Adult mosquitoes were collected indoors and outdoors using CDC light traps and human landing catches from March 2017 to March 2018 in 30 districts of Yaoundé, Cameroon. Mosquitoes were sorted by genus and identified to the species level using PCR. The TaqMan method and ELISA were used to determine mosquito infection status toPlasmodium. Bioassays were conducted to assess femaleAnopheles gambiaesusceptibility to insecticides.Results:A total of 218,991 mosquitoes were collected. The main malaria vectors were An.gambiaes.l. (n=6154) andAn. funestuss.l. (n=229). Of the 1476An. gambiaes.l. processed by PCR, 92.19% wereAn. coluzziiand 7.81%An. gambiae.An. funestuss.l. was composed of 93.01% (173/186)An. funestusand 4.84% (13/186)An. leesoni. The average biting rate of anopheline was significantly high outdoor than indoor (P=0.013). Seasonal variation in mosquito abundance and biting rate was recorded. The infection rate byPlasmodium falciparumwas 2.13% (104/4893 mosquitoes processed). The annual entomological inoculation rate was found to vary from 0 to 92 infective bites/man/year (ib/m/y). Malaria transmission risk was high outdoor (66.65 ib/m/y) compared to indoor (31.14 ib/m/y).An. gambiaes.l. was found highly resistant to DDT, permethrin and deltamethrin. High prevalence of the West Africakdrallele 1014F was recorded and this was not found to influenceAn. gambiaes.l. infection status. Conclusion: The study suggests high malaria transmission occurring in the city of Yaoundé and call for immediate actions to improve control strategies.
Долговременная динамика соотношения взрослых и молодых птиц у ближних и дальних мигрантов на осеннем пролете на Куршской косе Балтийского моря
Authors: Sokolov L. V. , Shapoval A. P. 
Published: December 2018

Было проанализировано соотношение взрослых и молодых птиц на осеннем пролете на Куршской косе Балтийского моря у 25 видов ближних и 19 дальних мигрантов в период с 1962 по 2016 гг. Сравнительный анализ показал, что доля взрослых особей среди пойманных в большие ловушки «рыбачинского типа» птиц была значимо выше у ближних мигрантов (19,4%), чем у дальних (5,4%). У видов, совершающих преимущественно дневные миграции, доля взрослых особей была выше, чем у ночных мигрантов (24,3% против 7,4% у ближних мигрантов и 7,4% против 4,5% – у дальних). У подавляющего большинства видов были выявлены значительные межгодовые колебания в соотношении взрослых и молодых особей. Однако значимые долговременные тренды в изменении этого соотношения были выявлены только у 3 видов ближних мигрантов и одного дальнего мигранта. Доля молодых особей, отлавливаемых на осеннем пролете, оказалась значимо связанной со средней температурой воздуха в Балтийском регионе весной и в начале лета (июнь): чем выше была температура в этот период, тем большая доля молодых птиц присутствовала в осенних отловах. Такая связь была выявлена у 8 видов ближних и 2 дальних мигрантов. Мы предполагаем, что это объясняется, в первую очередь, лучшей успешностью размножения этих видов в годы с высокой температурой воздуха весной и в начале лета в исследуемом регионе.
Омела окрашенная (Viscum coloratum (Kom.) Nakai) в Восточной Азии (таксономия, ареал, возможности использования)
Authors: Gorovoy P. G. , Balyshev M. E. , Krylov A. V. , Schekina V. V. , Nizkiy S. E. 
Published: December 2018

В работе представлены результаты исследования морфологических признаков и распространения в Восточной Азии Viscum coloratum (Kom.) Nakai с целью выявить специфические признаки этого вида и установить северную и северо-западную границы его ареала. Омела окрашенная на Дальнем Востоке представлена двумя формами: forma lutescens Kitag. и forma rubroaurantiacum (Makino) Kitag. В результате нашего исследования установлено, что северо-западная граница распространения омелы окрашенной достигает в Амурской области долины среднего течения реки Зеи. Впервые отмечается, что на Дальнем Востоке Viscum coloratum произрастает на Quercus mongolica (дуб монгольский). Омела окрашенная обильно поражает деревья липы около лесных пасек и в течение 20 лет заселяет почти все деревья, что вынуждает пчеловодов переносить пасеки в другие места. Среди распространителей плодов Viscum coloratum преобладают обыкновенные и японские свиристели. В народной медицине стран Восточной Азии омела окрашенная используется при лечении гипертонии и онкологических заболеваний. Основными противоопухолевыми веществами в водном экстракте омелы являются лектины.
Gadamer’s Hermeneutics as a Model For the Feminist Standpoint Theory
Authors: DEMİREZEN İsmail 
Published: December 2018

This
work which reconstructs Gadamer’s hermeneutics for guiding feminist standpoint
theory consists of five chapters. Firstly, several possible feminist standpoint
theories and their difficulties in addressing how knowledge is situated yet
true are clarified. Secondly, it will be examined that Gadamer’s proposal for
the relevance of the historicity on the reaching to truth. Thirdly, we will
discuss Gadamer’s notion of fusion of horizons as a way to reach to truth.
Fourthly, we will elaborate Wasterling’s critique against Gadamer and some
arguments that Gadamer’s hermeneutics substitutes feminist epistemology for
masculine epistemology. Finally, this
paper will evaluate Gadamer’s proposal for hermeneutics is appropriate for
feminist standpoint theory, if so, how it is appropriate.
İbn Nübâte El-Hatîb ve Hz. Hüseyin’in Şehâdeti ile İlgili Hutbesi
Authors: GEMİ Ahmet 
Published: December 2018

Arap edebiyat tarihinde adından sitayişle bahsedilen hatiplerden biri, İbn Nübâte’dir. 336/946 yılında Diyarbakır’ın Silvan (Meyyâfârikîn/Fârikîn) ilçesinde doğan İbn Nübâte, Hamdânîlerin Emîri Seyfüddevle b. Hamdân’ın (ö. 356/967) himayesinde bulunmuş ve sarayında hatiplik yapmıştır. Silvan ve Halep’te îrâd ettiği hutbelerle hak ettiği üne kavuşan İbn Nübâte’nin günümüze ulaşan hutbe mecmuası bulunmaktadır. İbn Nübâte, 374/984 yılında Silvan’da vefat etmiştir. Bazı kaynaklar Halep’te vefat ettiğini belirtmektedir. İbn Nübâte’nin muharrem ayının ikinci cuma gününe denk gelen hutbede îrâd ettiği Hz. Hüseyin’in şehit edilmesi ile ilgili olan hutbesi önemlidir. İbn Nübâte, bu hutbesinde Hz. Hüseyin’in şehadetinden dolayı üzüntüsünü dile getirmekte ve aynı şekilde Müslümanların da bu olaya üzülmeleri gerektiği üzerinde durmaktadır.
Adiponectin level in diabetic kidney disease the relationship with glycemic control and microvascular complications; a mystery unresolved
Authors: A. E. Tony Effat , H.Mostafa Mohamed , F. Abdelaal Refaat , A. Tony Abeer , El- Shereif Tahra , Adel A. Abdou Madleen 
Published: December 2018

Background: Defining new predictive biomarkers in diabetic kidney disease (DKD) would provide a window of opportunity for preventive and/or therapeutic interventions to prevent or delay the onset of irreversible long-term micro and or macro vascular complications. Adiponectin (ADPN) has been variously associated with diabetic microvascular complications; however, no comprehensive clinical data exist examining the association between adipocytokines and the presence of these complications.Aim of study: we aimed to measure the plasma levels of adiponectin in patients with type 2 diabetes mellitus, to assess whether these levels vary with the different stages of DKD according to their e GFR and to evaluate its relation to their microvascular complications and glycemic control.Methods: This is a prospective observational study including 100 T2DM classified into two groups according to their albuminuria levels and estimated GFR. Participants subjected to thorough history taking and clinical examination. Serum level of ADPN was assessed in all patients.Results: Serum ADPN levels were significantly lower in T2DM patients with nephropathy (P = 0.001), while their levels were non-significantly higher in patients with non-proliferative retinopathy or neuropathy. Their levels were lowered with more advanced stages of DKD with nephropathy and the decrement was dependent on their severity (P<0.001). Levels of ADPN with cutoff value of < 22600 (Î¼g/mL) had ability to diagnose microvascular complications in our diabetic patients with sensitivity (81%) and specificity (27%). Multivariate logistic regression analysis showed that the odds ratio for the presence of nephropathy in the lowest tertile of ADPN was 1.09 (95% CI; 11.45- 13.08, P= 0.06), therefore, ADPN was not an independent risk factor for diabetic nephropathy. However, its higher level was independently associated with increased odds for the presence of neuropathy in particular. Conclusions: ADPN plays a role in the pathogenesis of microvasculopathy in diabetic patients and help to identify high-risk patients and modulate the therapeutic potential in the prevention of DKD.Â Â
Estimation of the earth's albedo over some selected area the Republic of Chad
Authors: Marouf BARKA Zakaria , Lealea ThÃ©ophile , Tchinda Rene 
Published: December 2018

Surface albedo is one parameter of the climate variables. It influences the surface radiation budget for a given site. The availability of surface albedo data at both temporally and spatially levels are needed. In the lack of ground recorded values of albedo, we have to estimate surface albedo from the climatic variables. The model generated in this study enables the continuous observation of land surface albedo through relative model established from the multivariate regression method. From satellite recorded data, we estimate the ground surface albedo for some selected sites. The result were satisfactory with the root mean square error (RMSE) is 0.035. The Mean Absolute Error (MAE) was computed and indicated to be as low as 0.027 and mean absolute percentage error (MAPE) is 7.58.Â Â
One-photon Absorption Characterizations, Dipole Polarizabilities and Second Hyperpolarizabilities of Chlorophyll a and Crocin
Authors: Karakas A. , Ceylan Y. , Karakaya M. , Taser M. , Terlemez B. B. , Eren N. , El Kouari Y. , Lougdali M. , Arof A. K. , Sahraoui B. 
Published: December 2018

Abstract
The dispersion-free dipole polarizability (α) computations for chlorophyll a (1) and crocin (2) have been achieved by density functional theory (DFT) at B3LYP/ 6-31G(d) level. The measured one-photon absorption (OPA) wavelengths are quite consistence with the theoretically obtained values. Ab-initio quantum chemical calculations (time-dependent Hartree-Fock (TDHF)) have been implemented to reveal the static second hyperpolarizabilities (γ) and dynamic dipole polarizabilities of the title molecules. The examined compounds display γ with non-zero values, introducing their third-order nonlinear optical (NLO) phenomena. The first and second frontier molecular orbitals of the investigated molecules have been also derived from DFT.