bluuebunny/crossref_metadata_2025_split huggingface dataset:
KORELASI PANJANG LENGAN ATAS DENGAN TINGGI BADAN PADA WANITA SUKU BANJAR
Authors: Aflanie Iwan , Amalia Fitria , Mashuri Mashuri 
Published: August 2018

Abstract: The role of identification in the field of forensic medicine is the most important thing to the victims who have died. Identification is needed to reveal the identity of the corpse, one is needed to estimate the length of the corpse. The purpose of this research is analyzing the correlation between the length of upper arm with height in Banjarese student of Medical Faculty at Lambung Mangkurat University and to get height estimation formula based on the length of upper arm in Banjarese woman. The research methodology is the observational analytic with the cross sectional approach method. This research uses the purposive sampling method to take subject result with the total sample as many as 52 people. The Pearson test result showed that value p = 0,000 and value r = 0,933 for right upper arm and r = 0,928 for left upper arm, which indicated a very strong correlation between right and left upper arm with height in Banjarese woman. The conclusion from this research is that there is very strong correlation between the length of upper arm with height in Banjarese woman, with height estimation formula TB = 59,829 + 3,010 x PLAkn for right upper arm and TB = 59,618 + 3,020 x PLAkr for left upper arm. Keywords : identification, height estimation, Banjarese woman Abstrak: Peranan identifikasi dalam bidang ilmu kedokteran forensik merupakan hal paling penting pada korban yang telah meninggal. Identifikasi sangat dibutuhkan untuk mengungkapkan identitas mayat, salah satu yang diperlukan yaitu dengan memperkirakan panjang tubuh mayat tersebut. Tujuan penelitian ini yaitu menganalisis korelasi panjang lengan atas dengan tinggi badan pada mahasiswi suku Banjar di Fakultas Kedokteran Universitas Lambung Mangkurat dan untuk mendapatkan formula estimasi tinggi badan berdasarkan panjang lengan atas pada wanita suku Banjar. Metode penelitian ini yaitu observasional analitik dengan metode pendekatan cross sectional. Pengambilan subjek penelitian menggunakan metode purposive sampling dengan jumlah sampel sebanyak 52 orang. Hasil uji Pearson menunjukkan nilai p = 0,000 dan nilai r = 0,933 untuk lengan kanan dan r = 0,928 untuk lengan kiri, yang menunjukkan adanya korelasi yang sangat kuat antara panjang lengan atas kanan dan kiri dengan tinggi badan pada wanita suku Banjar. Kesimpulan dari penelitian ini yaitu terdapat korelasi yang sangat kuat antara panjang lengan atas dengan tinggi badan pada wanita suku Banjar, dengan formula estimasi tinggi badan TB = 59,829 + 3,010 x PLAkn untuk lengan kanan dan TB = 59,618 + 3,020 x PLAkr untuk lengan kiri. Kata-kata kunci : identifikasi, estimasi tinggi badan, wanita suku Banjar
KARAKTERISTIK PENDERITA TUBERKULOSIS PARU DENGAN MULTIDRUG-RESISTANT TUBERCULOSIS (MDR-TB) DI RSUD ULIN BANJARMASIN
Authors: Azwar Gusti Andhika , Noviana Dewi Indah , Hendriyono FX. 
Published: August 2018

Abstract: Tuberculosis is the main health problem in the world and getting worse with Multidrug-Resistant Tuberculosis (MDR-TB) cases. Many research about MDR-TB patients is conducted to describe MDR-TB patients characteristics. This research aims to describe the characteristics of pulmonary tuberculosis MDR-TB at RSUD Ulin Banjarmasin on December 2015-May 2016. This was a descriptive research with crossectional approaches. Data were collected from clinical pathology laboratory and patients medical record. The Result indicate that as many as 19 pulmonary TB patients with MDR-TB at RSUD Ulin Banjarmasin on December 2015-May 2016 with characteristics were dominated by men 84,2% (16 subjects); age 45-54 years 35,8% (7 subjects); junior and senior high school both 21,1% (4 subjects); private employees 31,6% (6 subjects); came with TB relapses 68,4% (13 subjects); and the acid-fast bacilli examination showed negative and positive both 21,1% (4 subjects). In conclusion, the characteristics of pulmonary tuberculosis patients with Multidrug-Resistant Tuberculosis (MDR-TB) at RSUD Ulin Banjarmasin on December 2015-May 2016 are dominated by men, age 45-54 years old, junior and senior high school, private employees, from Banjarmasin, come with TB relapses and the acid-fast bacilli examination showed negative and positive. Keywords: multidrug-resistant tuberculosis (MDR-TB), Tuberculosis patient’s characteristics, RSUD Ulin Banjarmasin Abstrak: Tuberkulosis merupakan masalah kesehatan utama di dunia dan bertambah berat dengan munculnya kasus multidrug-resistant tuberculosis (MDR-TB). Berbagai penelitian dilakukan untuk mengetahui karakteristik penderita MDR-TB. Oleh karena itu, penelitian ini bertujuan untuk mengetahui karakteristik penderita tuberkulosis paru dengan MDR-TB di RSUD Ulin Banjarmasin periode Desember 2015-Mei 2016. Penelitian ini adalah penelitian deskriptif dengan rancangan cross-sectional. Data diambil dari Laboratorium Patologi Klinik dan rekam medis penderita. Hasil penelitian menunjukkan 19 penderita tuberkulosis paru dengan MDR-TB di RSUD Ulin Banjarmasin periode Desember 2015-Mei 2016 didominasi oleh laki-laki 84,2% (16 orang); usia 45-34 35,8% (7 orang); pendidikan SMP dan SMA masing-masing 21,1% (4 orang); pekerja swasta 31,6% (6 orang); berasal dari Banjarmasin 57,9% (11 orang); datang dengan keadaaan TB kasus relaps kategori 1 dan kategori 2 68,4% (13 orang); dan dengan hasil pemeriksaan sputum BTA positif dan negatif masing-masing 21,1% (4 orang). Kesimpulan penelitian ini adalah karakteristik penderita tuberkulosis paru dengan multidrug-resistant Tuberculosis (MDR-TB) di RSUD Ulin Banjarmasin periode Desember 2015-Mei 2016 didominasi oleh laki-laki, usia 45-54 tahun, pendidikan SMP dan SMA, pekerja swasta, berasal dari Banjarmasin, datang dengan keadaan kasus TB relaps dan hasil sputum BTA negatif dan positif. Kata-kata kunci: Multidrug-resistant tuberculosis (MDR-TB), karakteristik penderita Tuberkulosis Paru
HUBUNGAN HIGIENITAS BOTOL SUSU DENGAN KEJADIAN DIARE DI WILAYAH PUSKESMAS KELAYAN TIMUR BANJARMASIN
Authors: Harris Muhammad Fathir Naman , Heriyani Farida , Hayatie Lisda 
Published: August 2018

Abstract: Diarrhea is a contagious disease which still become public health main issue in the world includes Indonesia. South Borneo is in the twentieth province with most frequent diarrhea incident. Kelayan Timur is the second most frequent diarrhea incident public health center in Banjarmasin. One of the risk factors for diarrhea is milk bottle hygiene. This research aimed to understand the correlation between milk bottle hygiene and diarrhea incident in Kelayan Timur Public Health Center. This was analytic observational research with case control study. The data analyzed using a chi square test and prevalence odds ratio. There were 66 samples with 33 samples of case group which showed 21 samples (63,63%) of poor milk bottle hygiene and 12 samples (36,36%) of good milk bottle hygiene meanwhile in control group, there were 11 samples (33,33%) of poor milk bottle hygiene and 22 sample (66,66%) of good milk bottle hygiene. Analysis result shows p value=0,014 and OR=3,5 which means there is significant relation of milk bottle hygiene and diarrhea incident in Kelayan Timur Public Health Center. Infants with poor hygiene milk bottle have 3,5 times higher risk to suffer from diarrhea than infants with good hygiene. Keywords: milk bottle hygiene, diarrhea, Kelayan Timur Public Health Center Abstrak: Diare adalah penyakit infeksi menular yang masih menjadi masalah utama kesehatan masyarakat di seluruh dunia termasuk Indonesia. Kalimantan Selatan menduduki urutan kedua puluh dari semua provinsi yang tercatat sebagai daerah penyumbang diare terbanyak. Kelayan Timur adalah puskesmas dengan kejadian diare terbanyak kedua di Banjarmasin. Salah satu dari faktor risiko diare adalah higienitas botol susu. Penelitian ini bertujuan untuk mengetahui hubungan higienitas botol susu dengan kejadian diare di wilayah Puskesmas Kelayan Timur. Penelitian bersifat observasional analitik dengan pendekatan case control. Analisis data menggunakan uji Chi-square dan prevalence odds ratio.Sampel yang diambil sebanyak 66 sampel, dimana 33 sampel yang diambil sebagai kelompok kasus menunjukkan 21 sampel (63,63%) dengan higienitas botol susu yang buruk dan 12 sampel (36,36%) dengan higienitas botol susu yang baik, sedangkan pada kelompok kontrol terdapat 11 sampel (33,33%) dengan higienitas botol susu yang buruk dan 22 sampel (66,66%) dengan higienitas botol susu yang baik. Hasil analisis mendapatkan nilai p=0,014 dan OR=3,5 sehingga dapat disimpulkan bahwa terdapat hubungan bermakna antara higienitas botol susu dengan kejadian diare di wilayah Puskesmas Kelayan Timur. Balita dengan higienitas botol susu yang buruk berisiko 3,5 kali lebih besar untuk menderita diare dibanding dengan higienitas botol susu yang baik. Kata-kata kunci:higienitas botol susu, diare, Puskesmas Kelayan Timur
AKTIVITAS LARVASIDA EKSTRAK ETANOL DAUN BINJAI (Mangifera caesia) TERHADAP LARVA Aedes aegypti
Authors: Nadila Isfarani , Istiana Istiana , Wydiamala Erida 
Published: August 2018

Abstract: Binjai leaf is known to have effective secondary metabolites as larvacide. The aim of this study was to recognize larvacidal effectivity of Binjai leaf ethanol extract toward Aedes aegypti larva. This was experimental study with posttest only control group design by using 7 treatment and 4 replication. Treatment was available from preliminary test which were 1000, 5000, 10.000, 15.000 and 20.000 (mg/L), negative xontrol (water) and positive control (themephos 100 mg/L). Probit test resulted in LC50 value=5493.390 mg/L and LC90 value=14988.861mg/L Kruskal-Wallis test resulted in p=0,000 which meaned there was an effect of binjai leaf ethanol extract toward Aedes aegypti larva. Meanwhile, Mann-Whitney test resulted in p=0,371 which meaned there was no significant difference between concentration of 20.000 mg/L and temephos 100 mg/L. In conclusion, binjai leaf (Mangifera caesia) ethanol extract have larvacidal activity as effective as temephos toward Aedes aegypti larva. Keywords: Larvacide, Binjai leaves, Aedes aegypti Abstrak: Daun binjai diketahui memiliki kandungan metabolit sekunder yang berpotensi sebagai larvasida. Tujuan penelitian ini adalah untuk mengetahui efektivitas larvasida ekstrak etanol daun binjai terhadap larva Aedes aegypti. Penelitian ini menggunakan jenis eksperimental dengan metode posttest only contol grup design menggunakan tujuh kelompok perlakuan dan 4 replikasi. Tujuh kelompok perlakuan tersebut adalah 5 serial konsentrasi yang diperoleh dari uji pendahuluan: 1000, 5000, 10.000, 15.000 dan 20.000 (mg/L), kontrol negatif (air) dan kontrol positif (temephos 100 mg/L). Hasil uji probit didapatkan nilai LC50 dan LC90 sebesar 5493.390 dan 14988.861 (mg/L). Uji kruskal-Wallis didapatkan nilai p=0,000, terdapat pengaruh ekstrak etanol daun binjai terhadap larva Aedes aegypti. Hasil uji Mann-whitney didapakan nilai p=0,371, tidak terdapat perbedaan signifikan antara konsentrasi 20.000 mg/L dengan kontrol positif. Kesimpulan dari penelitian ini ekstrak etanol daun binjai memiliki aktivitas larvasida dan efektivitas setara dengan temephos 100 mg/L terhadap larva Aedes aegypti. Kata-kata kunci : Larvasida, daun binjai, Aedes aegypti
CORRELATION TRIGLISERIDA LEVEL AND MONOCYTE IN CORONARY HEART DISEASE AT ULIN GENERAL HOSPITAL BANJARMASIN
Authors: Juwita Gusti Adistya Naila , Arifin Miftahul , Yuliana Ida 
Published: August 2018

Abstract: Coronary heart disease (CHD) is an unbalance condition between oxygen supply and demand in heart muscle which caused by coronary artery obstruction known as atherosclerosis. Both triglyceride and monocyte have important role in the process of atherosclerosis plaque forming which cause CHD. This research aimed to analyse correlation between triglyceride level and monocyte count in patients with coronary heart disease at Ulin General Hospital Banjarmasin on August 2014-August 2015. This research is an analytical observational research with cross-sectional approach. Total sample for this research are 94 CHD patients selected by inclusion criteria. The result discovered the average rate for triglyceride level is 114 mg/dL and for monocyte count is 0,62 thousand/µL. Based on result of data analysis with Pearson correlation test demonstrates the value of r=0,347 and p=0,01. It can be concluded that there is weak, significant and positive correlation between triglyceride level and monocyte count in CHD patients Keywords: triglyceride, monocyte, coronary heart disease
IMMATURE TO TOTAL NEUTROPHIL RATIO (I/T RATIO) ON NORMAL AND SEPSIS RISK NEONATUS FACTOR AT ULIN GENERAL HOSPITAL BANJARMASIN
Authors: Noor Muhammad Rifky Ersadian , Hendriyono F.X. , Yunanto Ari 
Published: August 2018

Abstract: Neonatal sepsis is the main cause of morbidity and mortality in neonates. Early diagnostic and appropriate treatment can reduce the mortality and morbidity rate. Immature neutrophil ratio tand total neutrophil (I/T ratio) can be used as one of early diagnostic tool of neonatal sepsis. The purpose of this research was to find difference of I/T ratio between normal neonates and neonates with sepsis risk factor at Ulin General Hospital Banjarmasin on April – June 2016. It was an analytic observational study and collected by accidental sampling. From 39 neonates, there was 23 normal neonates and 16 neonates with sepsis risk factor who diagnosed by competence pediatrics based on mayor and minor risk factor. Mean I/T ratio from normal neonates is 0,06 and neonates with sepsis risk factor is 0,16. From statistical test with independent T-test, there is significant difference p=0,000 (p<0,05). In conclusion, there is a difference of I/T Ratio between normal neonates and neonates with sepsis risk factor. Keywords: neonatal sepsis, I/T ratio, risk factor, neonates
CD4 LYMPHOCYTE IN HIV / AIDS BEFORE AND AFTER ANTIRETROVIRAL THERAPY
Authors: Prabowo Rangsang Bagus , Pertiwi Dewi Indah Noviana , Hendriyono FX. 
Published: August 2018

Abstract: Human Immunodefficiency Virus (HIV) is a virus that decreases the human immunity system, therefore the infected people become susceptible to any kind of infections. Examination of CD4 lymphocyte count periodically is one of the antiretroviral therapy success indicators. The purpose of this research was to determine the difference of CD4 lymphocyte count before and after antiretroviral therapy at Ulin General Hospital Banjarmasin on 2013-2015. The method of this research was observational analytic with cross-sectional approach. The study population was 55 patients which were selected by inclusion and exclusion criteria. Results portrayed an increase of the CD4 lymphocyte count in 51 patients after being given four kinds of antiretroviral for 6 months with the mean increase in CD4 lymphocyte count was 92,72 cell/µL. Data analysis result with Wilcoxon test portrayed a difference of the CD4 lymphocyte count before and after antiretroviral therapy with p value=0,000. In conclusion, there was a significant difference of the CD4 lymphocyte count before and after antiretroviral therapy. Keywords: Human Immunodeficiency Virus, CD4, lymphocyt, antiretroviral therapy
The Potential of Candida Biofilm Protein as Bioreceptor for Candidiasis Immunoassay
Authors: Masfufatun Masfufatun , Haryanto Loo , Harsono Harsono 
Published: August 2018

Abstract: Candidiasis or infection that is caused by Candida has become a new list of the therapeutical problems recently. The difficulties in diagnosing are the main cause of the unsatisfactory results from common therapies and diagnosis methods. This has urged researchers to find alternative ways in candidiasis diagnosis such as serology-based detection using antigen or antibody development. The aim of this study was to evaluate the potential of protein derived from Candida albicans biofilm as bioreceptor on candidiasis immunoassay through Dot Blot method. The research method used descriptive method with the following stages: (1) preparation of Candida albicans biofilm (2) extraction of Candida albicans protein through enzymatic and mechanical methods, (3) determination of protein molecular weight with SDS-PAGE (4) production of polyclonal anti- candida and (5) analysis of protein extract as bioreeceptor on dot blot. Profile of biofilm proteins on SDS-PAGE analysis were shown on molecular weight 27,42; 29,89; 38,10; 44,90; 48,75; 52,92; 55,14; 59,86; 70,56; 87,36; 102,54;115,05; 130,14;143,14;181,53 kD. There were differences in the intensity of dots in the control group (44070) and treatment groups (63170.5). It is noticeable that biofilm protein extract of C. albicans can be used for induction of anti-Candida polyclonal antibody production as the potential candidate of bioreceptor in candidiasis immunoassay. Keywords: SDS-PAGE, polyclonal antibody, immunoassay, dot blot, biofilm
Potency of Purple Yam (Dioscorea alata L) as an Immunomodulatory Agent
Authors: Makiyah Sri Nabawiyati Nurul , Djati Muhammad Sasmito 
Published: August 2018

Abstract: Purple yam tuber (Dioscorea alata L.) is one of tubers that has not been used optimally. One of the nutrients contained in Dioscorea species is Saponin Steroid. This paper aims to examine the potential of Steroid Saponin in purple yam tuber (Dioscorea alata L.) as an immunomodulatory agent. The method is by reviewing from various literatures. This article found that Steroid Saponin in purple yam tuber (Dioscorea alata L.) had a potency as an immunomodulatory agent. Keywords: Purple yam tuber (Dioscorea alata L), Steroid Saponin, Immunomodulatory
Current Non-viral siRNA Delivery Systems as a Promising Treatment of Skin Diseases
Authors: Rosa Juliana , Suzuki Isabella , Kravicz Marcelo , Caron Angelo , Pupo Ana Vitória , Praça Fabíola Garcia , Bentley Maria Vitória Lopes Badra 
Published: August 2018

Background:
Gene therapy is a new approach to discover and treat many diseases. It has attracted
considerable attention from researchers in the last decades. The gene therapy through RNA interference has been
considered one of the most recent and revolutionary approaches used in individualized therapy. In the last years,
we have witnessed the rapid development in the field of the gene silencing and knockdown by topical siRNA. Its
application in gene therapy has become an attractive alternative for drug development.

Methods:
This article will address topical delivery of siRNA as a promising treatment for skin disorders. An
update on the advances in siRNA-based nanocarriers as a powerful therapeutic strategy for several skin diseases
will be discussed giving emphasis on in vitro evaluations.

Results:
Through the in-depth review of the literature on the use of siRNAs for skin diseases we realize how
widespread this use is. We have also realized that nanoparticles as non-viral vectors are increasingly being explored.
Skin diseases where the use of siRNA has been explored most are skin cancer (melanoma and nonmelanoma),
psoriasis, vitiligo, dermatitis and leprosy. But we also report here other diseases where the use of
siRNA has been growing as acne, alopecia areata, cutaneous leishmaniasis, mycoses, herpes, epidermolysis bullosa
and oculocutaneous albinism. Also highlighted, the first clinical trial of siRNA for cutaneous diseases, aimed
at Pathyounychia Congenita.

Conclusion:
The treatment of skin diseases based on topical delivery of siRNA, which act by inhibiting the expression
of target transcripts, offers many potential therapeutic advantages for suppressing genes into the skin.
The Possible Impact of Hyperuricemia on Serum Soluble Receptor for Advanced Glycation end Products (sRAGE) Levels in Teenagers: A Case Control Study
Authors: Lemiesz Marta , Tenderenda-Banasiuk Edyta , Sosnowska Dorota , Rybi-Szumińska Agnieszka , Storonowicz Justyna , Lemiesz Tomasz , Wasilewska Anna 
Published: August 2018

Background:
Dietary advanced glycation end products (AGEs) and their interactions with the soluble
receptors for AGEs (RAGE) play a crucial role in the pathogenesis of cardiovascular diseases.

Objective:
This study was set out to assess, whether there was any association between serum sRAGE level and
serum uric acid level in children with hyperuricemia.

Methods:
This case-control study involved 53 patients (12 girls, 41 boys) with hyperuricemia (defined as serum
uric acid >4.8 and >5.5 mg/dl in girls and boys, respectively) aged (median [IQR]) (15.5 [13.5-15.5] years).
Thirty-six healthy individuals with normal serum uric acid level were selected as a reference group. Additionally,
the study group with hyperuricemia was divided into two groups: HU-HT (hypertensive n=25) and HU-NT (normotensive
n=28) teenagers. The serum concentration of human sRAGE was measured using a commercially
available enzyme-linked immunosorbent assay (ELISA) kit.

Results:
We found statistically significant differences in serum sRAGE levels between normotensive subjects
with hyperuricemia (median [IQR]) (169.8 [148.3-231.1] pg/ml) and reference group (median [IQR]) (129
[107.4-175.3] pg/ml), p<0.01. Univariate analysis of the data revealed a positive correlation between serum
sRAGE and serum uric acid in the study group (r=0.306, p<0.05).

Conclusion:
Our data showed that serum soluble receptors for AGEs are increased in teenagers with hyperuricemia.
In contrast, neither hypertension nor increased BMI had a significant influence on serum sRAGE concentration.
Further studies are needed to discover the possible mechanism on the influence of uric acid on sRAGE levels
and to assess its possible clinical significance.
The Action of Polyphenols in Diabetes Mellitus and Alzheimer's Disease: A Common Agent for Overlapping Pathologies
Authors: Silveira Ana C. , Dias Jane Pires , Santos Vanessa M. , Oliveira Pedro Fontes , Alves Marco G. , Rato Luís , Silva Branca M. 
Published: August 2018

:Diabetes Mellitus (DM) and Alzheimer's disease (AD) are two prevalent diseases in modern societies, which are caused mainly by current lifestyle, aging and genetic alterations. It has already been demonstrated that these two diseases are associated, since individuals suffering from DM are prone to develop AD. Conversely, it is also known that individuals with AD are more susceptible to DM, namely type 2 diabetes (T2DM). Therefore, these two pathologies, although completely different in terms of symptomatology, end up sharing several mechanisms at the molecular level, with the most obvious being the increase of oxidative stress and inflammation.:Polyphenols are natural compounds widely spread in fruits and vegetables whose dietary intake has been considered inversely proportional to the incidence of DM and AD. So, it is believed that this group of phytochemicals may have preventive and therapeutic potential, not only by reducing the risk and delaying the development of these pathologies, but also by improving brain’s metabolic profile and cognitive function.:The aim of this review is to understand the extent to which DM and AD are related pathologies, the degree of similarity and the relationship between them, to detail the molecular mechanisms by which polyphenols may exert a protective effect, such as antioxidant and anti-inflammatory effects, and highlight possible advantages of their use as common preventive and therapeutic alternatives.