bluuebunny/crossref_metadata_2025_split huggingface dataset:
Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries
Authors: Overbeek Jetty A. , van Herk-Sukel Myrthe P.P. , Vissers Pauline A.J. , van der Heijden Amber A.W.A. , Bronsveld Heleen K. , Herings Ron M.C. , Schmidt Marjanka K. , Nijpels Giel 
Published: January 2019

OBJECTIVE
To investigate whether women with type 2 diabetes (T2D) develop a more advanced stage of breast cancer and whether treatment with insulin (analogs) is associated with specific breast cancer characteristics.

RESEARCH DESIGN AND METHODS
For this nested case-control study, women with breast cancer diagnosed in 2002–2014 were selected from the linked Netherlands Cancer Registry–PHARMO Database Network (N = 33,377). T2D was defined as receiving two or more dispensings of noninsulin blood glucose–lowering drugs prior to breast cancer diagnosis. Women with T2D were matched to women without diabetes. Among women with T2D, insulin users and nonusers were compared. Multivariable ordinal logistic regression was used to investigate the association between T2D/insulin and breast cancer characteristics, including TNM classification (tumor size, lymph node status, metastasis), morphology, grade, estrogen receptor and progesterone receptor (PR), human epidermal growth factor receptor 2, and molecular subtype.

RESULTS
Women with T2D (n = 1,567) were more often diagnosed with a more advanced tumor stage (odds ratio 1.28 [95% CI 13–1.44]) and a higher grade (1.22 [1.08–1.39]) though less often with a PR-negative breast tumor (0.77 [0.67–0.89]) than women without diabetes (n = 6,267). No associations were found for the other breast cancer characteristics. Women with T2D using insulin (n = 388) were not diagnosed with different breast cancer characteristics compared with women with T2D not using insulin (n = 1,179).

CONCLUSIONS
Our study suggests that women with T2D are at increased risk to be diagnosed with a more aggressive type of breast cancer than women without diabetes. No evidence was found that the use of insulin (analogs) is associated with developing more advanced breast cancer tumors.
Doa Search and Retrieval Using N-Gram
Authors: Abu Mangshor Nur Nabilah , Sabri Nurbaity , Ibrahim Zaidah , Kasiran Zolidah , Ahmad Anis Safura 
Published: January 2019

‘Doa’ is derived from Arabic word which means that one asks for the fulfillment or a need or the cure of sickness from him/her. Having to search and retrieve the relevant ‘doa’ for one needs at any particular time is beneficial. There are some search and retrieval applications that require using the exact match of the keyword search with the words stored in the database. This approach leads to the retrieval of insignificant results as users need to know the exact word to be searched. Therefore, this project allows for partial keyword search that utilises N-gram method for the search and retrieval process. Moreover, various words may have similar meaning thus to increase the accuracy of the retrieved result, this project compares the dice and overlap coefficient algorithms to find the synonyms of the searched word. The result produced indicates that overlap coefficient perform better than dice coefficient.
Optimal Electric-Power Distribution and Load-Sharing on Smart-Grids: Analysis by Artificial Neural Network
Authors: De Groff Dolores , Melendez Roxana , Neelakanta Perambur , Akif Hajar 
Published: January 2019

This study refers to developing an electric-power distribution system with optimal/suboptimal load-sharing in the complex and expanding metro power-grid infrastructure. That is, the relevant exercise is to indicate a smart forecasting strategy on optimal/suboptimal power-distribution to consumers served by a smart-grid utility. An artificial neural network (ANN) is employed to model the said optimal power-distribution between generating sources and distribution centers. A compatible architecture of the test ANN with ad hoc suites of training/prediction schedules is indicated thereof. Pertinent exercise is to determine smartly the power supported on each transmission-line between generating to distribution-nodes. Further, a “smart” decision protocol prescribing the constraint that no transmission-line carries in excess of a desired load. An algorithm is developed to implement the prescribed constraint via the test ANN; and, each value of the load shared by each distribution-line (meeting the power-demand of the consumers) is elucidated from the ANN output. The test ANN includes the use of a traditional multilayer architecture with feed-forward and backpropagation techniques; and, a fast convergence algorithm (deduced in terms of eigenvalues of a Hessian matrix associated with the input data) is adopted. Further, a novel method based on information-theoretic heuristics (in Shannon’s sense) is invoked towards model specifications. Lastly, the study results are discussed with exemplified computations using appropriate field data.
CORRELAÇÃO ENTRE INTERNAÇÕES POR MICOSES E CONDIÇÕES CLIMÁTICAS EM SÃO LUÍS, NO PERÍODO DE 1998 A 2016
Authors: Silva Letícia Chagas da , Santos Jessflan Rafael Nascimento , Pinheiro Edilene De Araújo Diniz , Mendes Amanda Graziela Gonçalves , Araújo Mayara Lucyanne Santos de , Almeida Juliana Lopes , Silva Fabrício Brito , Santos Julliana Ribeiro Alves dos 
Published: January 2019

As micoses sistêmicas representam um problema de saúde pública no Brasil e são doenças endêmicas em alguns estados, como no Maranhão. São causadas por fungos que estão presentes no ambiente associados ao solo, vegetais, materiais em decomposição e excretas de aves. As condições climáticas podem influenciar a proliferação e a disseminação destes agentes, contribuindo com o aumento do número de casos de internações. Neste contexto, o objetivo deste estudo foi avaliar a correlação entre as condições climáticas e as internações por micoses em São Luís (MA), no período de 1998 a 2016. Após a aprovação do Comitê de Ética em Pesquisa da Universidade CEUMA, a coleta de dados secundários referentes aos aspectos climáticos e de internações por micoses foi realizada em bases nacionais. A análise de Correlação de Spearman foi aplicada para os dados mensais de internações por micoses e precipitação ou temperatura máxima/ mínima. Foram registrados 786 casos de internações por micoses em São Luís, no período avaliado. Uma correlação positiva entre a precipitação (p< 0,05) e o número de internações por micoses foi observada, enquanto para as temperaturas mínima (p< 0,05) e máxima (p> 0,05), as correlações foram negativas. Os resultados deste estudo destacam que quanto maior a temperatura, menor o número de internações por micoses em São Luís. Este estudo destaca a importância da vigilância epidemiológica das micoses no Estado do Maranhão e da avaliação da modulação das condições ambientais na proliferação de fungos patogênicos. PALAVRAS-CHAVE: São Luís, fungos, precipitação, temperatura.
EFEITOS DO USO DE UM PROGRAMA CINESIOTERAPÊUTICO NA FORÇA DE PREENSÃO MANUAL DE IDOSAS
Authors: Vieira Jose Newton Lacet , Mendonça Thaisa Veloso , Rego Adriana Sousa , Silva Flor De Maria Araújo Mendonça 
Published: January 2019

Objetivo: Verificar os efeitos do uso de um programa cinesioterapêutico na força de preensão manual de idosas. Materiais e Métodos: Estudo experimental, analítico realizado no período de outubro/novembro de 2013, no clube de repouso Irmã Dulce e na Associação Comunitária da Vila Cruzado, tendo envolvido 30 idosas pertencentes a 02 grupos de convivências, com idade igual ou superior a 60 anos, sendo que 20 idosas fizeram parte de um grupo experimental e 10 idosas fizeram parte de um grupo controle. Todas foram avaliadas quanto a força muscular máxima de preensão manual, com uso do equipamento dinamômetro mecânico. Em seguida, apenas o grupo de 20 idosas iniciou o programa cinesioterapêutico. Após 02 meses, todas as idosas foram reavaliadas. Para análise dos dados foi usado o programa estatístico SPSS 18.0. Na estatística descritiva, as variáveis quantitativas com distribuição simétrica são apresentadas em média e desvio padrão e as assimétricas em mediana, mínimo e máximo. Para a análise do efeito do programa cinesioterapêutico na força de preensão manual de idosas e na comparação intergrupos foi utilizado o teste de Wilcoxon. Na análise da relação entre força de preensão manual e faixa etária das idosas submetidas ao programa cinesioterapêutico foi utilizado o Kruskal-Wallis, sendo considerado significativo p<0,05. Resultados: Não foi verificada diferença significativa com relação à idade e peso corporal, por parte dos 02 grupos de idosas avaliadas. Foi verificada diferença estatisticamente significativa apenas no grupo de idosas submetidas ao programa cinesioterapêutico, quanto à força de preensão manual. Conclusão: Idosas submetidas a um programa cinesioterapêutico, mesmo que durante um curto período, apresentam aumento da força de preensão manual.
Virtual Acoustics for Concert Advertisement
Authors: Batke Johann-Markus 
Published: January 2019

"Vision Kirchenmusik" is a project group to find new concepts for presenting church music. One of the most recent projects is the concert advertisement and preparation presenting the St. Luke Passion composed by Krzystof Penderecki. This contribution reports on the audio production carried out for a guided inner city walk presenting light art and sound installations. In particular, the binaural synthesis of reverbusing Higher Order Ambisonics is discussed.
Pemanfaatan Kompos Ela Sagu, Sekam Dan Dedak Sebagai Media Perbanyakan Agens Hayati Trichoderma harzianum Rifai.
Authors: Uruilal Costanza , Kalay A. Marthin , Kaya Elizabet , Siregar Adelina 
Published: January 2019

The use of biological agents to prevent the growth of plant diseases is aimed at decreasing the capability of particular pathogen, preventing their growth and spread, reducing the infection and intensity of pathogenic attack to main plants. Trichoderma harzianum is commonly found in almost all types of soil, and is one of fungi that can be used as biological agents to control plant pathogens. Growth and development of this fungi are mostly influenced by factors such as temperature, light, air, and pH. It is also dependents on other nutrients such as carbon, nitrogen and plain carbohydrate which are contained in sago waste (ela), bran and rice husk. The objective of this study is to find out the utilization of sago waste, bran and rice husk as media to multiply the biological agents T. harzianum. The result of this study showed that sago waste compost could be used as a medium to multiply the antagonist T. harzianum; when appropriately mixed with bran and rice husk (1:1:1 v/v), sago waste composts would be an effective media to develop the T. harzianum fungus. This mixture is better compared to sago waste composts, husk, sago waste composts and bran, and sago waste composts and husk. It is doe to the fact that in the media number of spore of T. harzianum (7,08 x 109/mL) increased and colony characteristics was dense..
Dampak Perubahan Penggunaan Lahan Terhadap Aliran Permukaan, Aliran Bawah Permukaan Dan Aliran Dasar Di Das Batugajah Kota Ambon
Authors: Soplanit Ruddi , Silahooy Charles 
Published: January 2019

The study was conducted to quantify the land use changes that have occurred in the watershed Batugajah and evaluate the impact of changes in land use to changes in surface flow, inter flow and base flow. The results showed that the change in land use in the watershed Batugajah of the year 1998-2010 as follows: The decline occurred from 215.70 ha forest area to forest area 58.88 ha or 28.73% decrease, increasing the wide use of residential land of 25 ha to 183.62 ha, an increase of 29.06%; vast improvement hamlet of 155, 65 ha to 221.78 ha, an increase of 12.12%. The impact of land use changes as follows: Runoff increased from 2288.35 mm to 2291.35 mm; annual runoff increased from 2525.81 mm to 2646.70 mm; interflo) increased from 103.382 mm to 244.99 mm; Water yield increased from 210.48 mm to 220.56 mm and the base flow dropped 141.07 mm to 110.35 mm.
Serangan Perenosclerospora spp Pada Tanaman Jagung Di Desa Rumahtiga, Kecamatan Teluk Ambon Baguala Kota Ambon
Authors: Matruti Angel E , Kalay A. Marthin , Uruilal Costanza 
Published: January 2019

Peronosclerospora spp. is one of the fungal pathogen that causes downy mildew on corn, and can cause yield losses up to 100%. Field research has been done to determine the development of Perenosclerospora spp. attack and contributing factors on corn at corn plantation in Rumahtiga village. The experiment was conducted by using survey method at local farmer’s plantation where they cultivated corn in Taeno Hamlet, Talaga Pange, Air Ali, and Wailela areas. The results showed that downy mildew development in corn reached 8.92% which is belong to low diseases intensity. Cultivation techniques including the use of hybrid varieties C1, appropriate fertilization, crop rotation and weed control, as well as good sanitation were key factors of low scale infestation of Peronosclerospora spp.
Uji Antagonis Pseudomonas sp. Asal Endofit Perakaran Padi Terhadap Penyakit Blas (Pyricularia oryzae) Secara In Vitro
Authors: Saylendra Andree , Rusbana Tubagus Bahtiar , Herdiani Linda 
Published: January 2019

The purpose of this research was to determine the antagonistic bacteria Pseudomonas spp. of paddy roots endophytic against disease blast (Pycularia oryzae) in vitro. This research was conducted at the Laboratory of Agroecology, Faculty of Agriculture, University of Sultan Ageng Tirtayasa on April to June 2015. This research implemented experimental one factor that arranged in Completely Randomized Design with three replications. The treatment consisted of 9 isolates of Pseudomonas sp. which was screened from endophytic roots of paddy plants. The test results showed that antagonistic in vitro testing could inhibit the growth P. oryzae. Inhibition of 9 isolates to the growth Pseudomonas spp. had the significant clear zone. Isolate Ps 17 (58.89%), Ps 22 (54.44%), Ps 37 (52.06%) and Ps 39 (61.42%) have the largest inhibition. The results showed that the bacteria Pseudomonas sp. on this research is potential on controlling disease blast in paddy plant.
COMPARATIVE ANALYSIS OF METHODS OF CALCULATION AND ERRORS OF ACTIVE POWER LOSSES IN LOW VOLTAGE COMMERCIAL NETWORKS
Authors: Gracheva E. I. , Sadykov R. R. , Khusnutdinov R. R. 
Published: January 2019

The article analyzes some methods for calculating the loss of active power in lowvoltage industrial networks, taking into account the main influencing parameters. Equivalent resistance and losses of active power in radial and trunk circuits are determined. The errors of the equivalent resistance and the loss of the active power of the circuits relative to the reference values are calculated. Graphic dependencies of the equivalent resistance of the radial and trunk circuits of the industrial networks are taken into account, taking into account switching devices on the lines in the functions of such parameters as the total cross-section of lines, average lengths, cross-sections of lines and ambient temperature, and with a change in the line load factor. The proposed nomograms are highly accurate and can be used in practical calculations.
Studi Pemanfataan Limbah Terak Timah 2 Bangka Sebagai Sumber Sekunder Unsur Skandium
Authors: Kartika Wahyu , Majid Rafdi Abdul , Navanti Dovina 
Published: January 2019

Terak timah (tin slag) adalah sisa dari pengolahan timah yang mengandung radioaktif dan cenderung menjadi limbah karena pemanfaatannya yang belum maksimal. Studi ini bertujuan untuk memanfaatkan limbah terak timah sebagai sumber sekunder unsur skandium sehingga pemanfaatannya dapat meminimalkan risiko paparan radioaktif terhadap lingkungan. Skandium banyak digunakan sebagai solid oxide fuel cells (SOFC’s) dapat menyebabkan reaksi terjadi pada temperatur yang lebih rendah, dalam bidang metalurgi sebagai paduan kekuatan tinggi aluminium, dalam bidang keramik penambahan skandium karbida akan meningkatkan kekerasan, lampu metal halida dengan intensitas tinggi, elektronik, dan penelitian laser. Penelitian ini menggunakan sampel terak timah 2 Bangka (TTB). Pada tahap awal TTB dipanaskan sampai suhu 900⁰C, lalu dicelupkan ke dalam air, dikeringkan dan di ayak (terak timah 2 Bangka yang dipanaskan, dicelup ke dalam air dan diayak, disebut TTB-PCA). Studi pertama, TTB-PCA yang dilarutkan ke dalam asam florida (disebut kode sampel F) dan studi kedua, TTB-PCA dilarutkan ke dalam HCl kemudian dilarutkan ke dalam NaOH (disebut kode sampel AB). TTB, TTB-PCA, kode sampel F dan AB dilakukan karakterisasi dengan X-Ray Fluorescence (XRF). Hasil karakterisasi memperlihatkan kadar skandium di dalam TTB sebesar 319 ppm dan kadar skandium tertinggi pada TTB-PCA dengan ukuran butir 200 mesh sebesar 804 ppm. Pada penelitian digunakan software HSC Chemistry 6 sebagai pendukung diskusi termodinamika. Kata Kunci: terak timah Bangka, software hsc chemistry 6, limbah padat, skandium, pelarutan ABSTRACT - Tin slag is the waste of tin processing that contains radioactive and tends to become waste due to its not maximal utilization. This study aims to utilize waste tin slag as a secondary source of scandium element so that its utilization can minimize the risk of radioactive exposure to the environment. Scandium widely used as solid oxide fuel cells (SOFC's) can cause reactions to occur at lower temperatures, in the field of metallurgy as high-strength aluminum alloys, in the field of ceramic addition of scandium carbide will increase hardness, metal halide lamps with high intensity, electronics, and laser research. This research used Bangka tin slag 2 (TTB), the initial stage of TTB was roasted to 900°C, then water quenched, dried and sieved (TTB roasted, water quenched and sieved, called TTB -PCA). The first study, TTB-PCA dissolved into fluoride acid (called code sample F) and a second study, TTB-PCA dissolved into HCl and then dissolved into NaOH (called AB code sample). TTB, TTB-PCA, sample code F and AB are characterized by X-Ray Fluorescence (XRF). The characterization results show scandium content in TTB of 319 ppm and the highest scandium content in TTB-PCA with grain size of 200 mesh of 804 ppm. In the study used HSC Chemistry 6 software as a supporter of thermodynamic discussion.Keywords: bangka tin slag, hsc chemistry 6 software, solid waste, scandium, dissolution
OPTIMASI FORMULA GEL SERBUK DAGING LIMBAH TOMAT (Licopersicum asculentum Mill) DAN UJI AKTIVITAS TERHADAP LAMA PENYEMBUHAN LUKA EKSISI PADA KELINCI
Authors: Ittiqo Dzun Haryadi , Fitriana Yuli 
Published: January 2019

Abstrak: Obat topikal sintesis yang umum digunakan pada luka eksisi adalah povidon iodium, tetapi penggunaan yang berlebihan dapat menimbulkan efek samping berupa dermatitis, bengkak, gatal dan rangsangan nyeri pada daerah sekitar luka sehingga diperlukan alternatif obat alami yang lebih aman dan memiliki efektifitas yang sama dengan bahan sintetik. Senyawa golongan flavonoid telah dibuktikan secara pre klinis bisa mempercepat penyembuhan luka. Tomat mengandung senyawa golongan flavonoid. Sehingga diperkirakan memiliki potensi sebagai obat penyembuh luka.Penelitian ini merupakan penelitian eksperimental, daging limbah buah tomat dibuat serbuk kering halus. Optimasi formula gel serbuk daging limbah tomat menggunkan software design exspert versi 7.1.5. Komponen yang dioptimasi adalah Na-CMC dan propilenglikol, respon yang dinilai adalah daya sebar. Uji efektivitas formula optimum gel terhadap lama penyembuhan luka eksisi, hewan uji dibagi dalam empat kelompok yaitu kelompok kontrol positif ( betadin zalp 10%), formula optimum gel, kontrol negativ, dan tanpa bahan uji (basis gel). Punggung kelinci dibuat luka eksisi sepanjang 3cm dengan kedalaman 0,3 cm, luka diolesi sampel uji sebanyak tiga kali sehari selama 8 hari. Pengamatan dilakukan dengan mengukur panjang luka selama perlakuan.Hasil optimasi formula menggunakan D-optimal Design didapatkan Persentase perbandingan penyusun gel yang optimal yaitu CMC-Na dan Propilenglokol masing-masing adalah 5,50%, dan 4,50%. dengan respon daya sebar 8,15 cm2, dan Daya lekat 18,51 detik. Uji efektivitas formula optimal gel serbuk daging limbah tomat (Licopersicum asculentum Mill) menunjukkan aktivitas penyembuhan luka yang sama dengan betadin zalp 10% dengan nilai mean±SD masing-masing 1,925±1,033 dan 1,729 ±1,021.Kata Kunci: Gel; Limbah tomat; D-optimal design; Luka eksisi
Zur Kontroverse um das Überakkumulationstheorem
Authors: Kleinknecht Alfred 
Published: January 2019

Die von Makoto Itoh in der Prokla Nr. 22 (,,Die Entwicklung der Krisentheorie bei Marx") ausgearbeitete Position läßt sich folgendermaßen zusammenfassen: Bei Marx findet sich noch keine ,,fertige" Theorie des Akkumulations- und Krisenzyklus', Allerdings gibt es im Marxschen Gesamtwerk verschiedene Ansätze der Krisenerklärung, deren Verhältnis zueinander weitgehend ungeklärt bleibt.Ihto hebt vor allem zwei Ansätze hervor, die auch in der gegenwärtigen Krisendiskussion eine wichtige Rolle spielen (1) und die in bezug auf die Bestimmung der letztendlichen Ursache der Krise logisch unvereinbar sind: Zum einen handelt es sich um die Überakkumulationstheorie der Krise (2), die aus der Überakkumulation des Kapitals den Fall der Profitrate ableitet und die Überproduktion von Waren als deren Folgeerscheinung behandelt. Dem entgegengesetzt steht die Theorie der Überproduktion bzw. Unterkonsumtion, die aus den Schranken des Marktes (insbesondere aufgrund der „Armut und Konsumbeschränkung der Massen ... ", MEW 25, S. 501) die Überproduktion von Waren und als deren Folge den Fall der Profitrate und die Überakkumulation des Kapitals ableitet.
Blue Ocean Strategy In Managing Maritime Security
Authors: Poerwowidagdo Sapto J. 
Published: January 2019

<p align="justify">The impact of the extension of the sea area of Indonesia, the biggest archipelagic state, is the bigger task of the Indonesian Navy and the other institutions and stake holder of the maritime security. The overlapping of the responsibility and authority in the maritime security tasks, pushes the Indonesian Navy in optimizing its main task. In the scope of the Maritime Domain Awareness, the Blue Ocean Strategy might be considered in managing an integrated maritime security by using Revolution in Navy Affairs in the Indonesian sea-power building.</p><p align="justify"><strong>Keywords:</strong> Archipelagic state, Maritime domain awareness, Blue ocean strategy, Revolution in navy affairs.</p>