bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-M–Induced Delayed Hemolytic Transfusion Reaction
Authors: Fadeyi Emmanuel A , Naal Tawfeq , Green Mary , Simmons Julie H , Jones Mary Rose , Pomper Gregory J 
Published: September 2019

Abstract

Background
Anti-M is most often assumed to be naturally occurring and can be comprised of a mixture of predominantly immunoglobulin(Ig)M with a lesser IgG component. Anti-M-antibodies usually do not react at 37°C and therefore are considered to be of little clinical significance.

Methods
A 28-year-old man presented with hemorrhagic shock from numerous injuries sustained in a motor vehicle collision. The patient received several units of red blood cells (RBCs). The antibody screen, the direct antiglobulin test (DAT), and the RBC genotype were sent for laboratory evaluation.

Results
A total of 12 days after the first antibody screening result was negative (7 days after transfusion), the lowest hemoglobin value was 5.5 g per dL, and we observed a positive antibody screening result and DAT with immunoglobulin (Ig)G anti-M identified. After transfusion of 4 units of M antigen–negative RBC, the post-transfusion hemoglobin level increased to 8.9 g per dL.

Conclusion
Obtaining M antigen–negative compatible RBCs is necessary in patients demonstrating IgG anti-M in plasma.
The SLUGGS survey: measuring globular cluster ages using both photometry and spectroscopy
Authors: Usher Christopher , Brodie Jean P , Forbes Duncan A , Romanowsky Aaron J , Strader Jay , Pfeffer Joel , Bastian Nate 
Published: September 2019

ABSTRACT
Globular cluster ages provide both an important test of models of globular cluster formation and a powerful method to constrain the assembly history of galaxies. Unfortunately, measuring the ages of unresolved old stellar populations has proven challenging. Here, we present a novel technique that combines optical photometry with metallicity constraints from near-infrared spectroscopy in order to measure ages. After testing the method on globular clusters in the Milky Way and its satellite galaxies, we apply our technique to three massive early-type galaxies using data from the SAGES Legacy Unifying Globulars and GalaxieS (SLUGGS) survey. The three SLUGGS galaxies and the Milky Way show dramatically different globular cluster age and metallicity distributions, with NGC 1407 and the Milky Way showing mostly old globular clusters, while NGC 3115 and NGC 3377 show a range of globular ages. This diversity implies different galaxy formation histories and that the globular cluster optical colour–metallicity relation is not universal as is commonly assumed in globular cluster studies. We find a correlation between the median age of the metal-rich globular cluster populations and the age of the field star populations, in line with models where globular cluster formation is a natural outcome of high-intensity star formation.
Upgraded Giant Metrewave Radio Telescope timing of NGC 1851A: a possible millisecond pulsar − neutron star system
Authors: Ridolfi A , Freire P C C , Gupta Y , Ransom S M 
Published: September 2019

ABSTRACT
In this work, we present the results of 1 yr of upgraded Giant Metrewave Radio Telescope timing measurements of PSR J0514−4002A, a 4.99-ms pulsar in a 18.8-d eccentric ($e = 0.89$) orbit with a massive companion located in the globular cluster NGC 1851. Combining these data with earlier Green Bank Telescope data, we greatly improve the precision of the rate of advance of periastron, $\dot{\omega} = 0.0129592(16)\, \deg \, \rm yr^{-1}$ which, assuming the validity of general relativity, results in a much refined measurement of the total mass of the binary, $M_{\rm tot} = 2.4730(6) \, \mathrm{M}_{\odot }$. Additionally, we measure the Einstein delay parameter, γ, something that has never been done for any binary system with an orbital period larger than ${\sim}$10 h. The measured value, $\gamma = 0.0216(9) \, \rm s$, is by far the largest for any binary pulsar. Furthermore, we measure the proper motion of the system ($\mu _{\alpha } = 5.19(22)$ and $\mu _{\delta } = -0.56(25)\rm ~mas ~ yr^{-1}$), which is not only important for analysing its motion in the cluster, but is also essential for a proper interpretation of γ, given the latter parameter’s correlation with the variation of the projected semimajor axis. The measurements of γ and the proper motion enable a separation of the system component masses: we obtain a pulsar mass of $M_{\rm p} = 1.25^{+0.05}_{-0.06} \, \mathrm{M}_{\odot }$ and a companion mass of $M_{\rm c} = 1.22^{+0.06}_{-0.05} \, \mathrm{M}_{\odot }$. This raises the possibility that the companion is also a neutron star. Searches for radio pulsations from the companion have thus far been unsuccessful; hence, we cannot confirm the latter hypothesis. The low mass of this millisecond pulsar – one of the lowest ever measured for such objects – clearly indicates that the recycling process can be achieved with a relatively small amount of mass transfer.
Characterization of the planetary nebula Tc 1 based on VLT X-shooter observations
Authors: Aleman Isabel , Leal-Ferreira Marcelo L , Cami Jan , Akras Stavros , Ochsendorf Bram , Wesson Roger , Morisset Christophe , Cox Nick L J , Bernard-Salas Jeronimo , Paladini Carlos E , Peeters Els , Stock David J , Monteiro Hektor , Tielens Alexander G G M 
Published: September 2019

ABSTRACT
We present a detailed analysis of deep VLT/X-Shooter observations of the planetary nebula Tc 1. We calculate gas temperature, density, extinction, and abundances for several species from the empirical analysis of the total line fluxes. In addition, a spatially resolved analysis of the most intense lines provides the distribution of such quantities across the nebula. The new data reveal that several lines exhibit a double peak spectral profile consistent with the blue and redshifted components of an expanding spherical shell. The study of such components allowed us to construct for the first time a three-dimensional morphological model, which reveals that Tc 1 is a slightly elongated spheroid with an equatorial density enhancement seen almost pole on. A few bright lines present extended wings (with velocities up to a few hundred km s−1), but the mechanism producing them is not clear. We constructed photoionization models for the main shell of Tc 1. The models predict the central star temperature and luminosity, as well as the nebular density and abundances similar to previous studies. Our models indicate that Tc 1 is located at a distance of approximately 2 kpc. We report the first detection of the [Kr iii] 6825 Å emission line, from which we determine the Krypton abundance. Our model indicates that the main shell of Tc 1 is matter bounded; leaking H ionizing photons may explain the ionization of its faint AGB-remnant halo.
Persistence of the colour–density relation and efficient environmental quenching to z ∼ 1.4
Authors: Lemaux B C , Tomczak A R , Lubin L M , Gal R R , Shen L , Pelliccia D , Wu P-F , Hung D , Mei S , Le Fèvre O , Rumbaugh N , Kocevski D D , Squires G K 
Published: September 2019

ABSTRACT
Using ∼5000 spectroscopically confirmed galaxies drawn from the Observations of Redshift Evolution in Large Scale Environments (ORELSE) survey we investigate the relationship between colour and galaxy density for galaxy populations of various stellar masses in the redshift range 0.55 ≤ z ≤ 1.4. The fraction of galaxies with colours consistent with no ongoing star formation (fq) is broadly observed to increase with increasing stellar mass, increasing galaxy density, and decreasing redshift, with clear differences observed in fq between field and group/cluster galaxies at the highest redshifts studied. We use a semi-empirical model to generate a suite of mock group/cluster galaxies unaffected by environmentally specific processes and compare these galaxies at fixed stellar mass and redshift to observed populations to constrain the efficiency of environmentally driven quenching (Ψconvert). High-density environments from 0.55 ≤ z ≤ 1.4 appear capable of efficiently quenching galaxies with $\log (\mathcal {M}_{\ast }/\mathcal {M}_{\odot })\gt 10.45$. Lower stellar mass galaxies also appear efficiently quenched at the lowest redshifts studied here, but this quenching efficiency is seen to drop precipitously with increasing redshift. Quenching efficiencies, combined with simulated group/cluster accretion histories and results on the star formation rate-density relation from a companion ORELSE study, are used to constrain the average time from group/cluster accretion to quiescence and the elapsed time between accretion and the inception of the quenching event. These time-scales were constrained to be 〈tconvert〉 = 2.4 ± 0.3 and 〈tdelay〉 = 1.3 ± 0.4 Gyr, respectively, for galaxies with $\log (\mathcal {M}_{\ast }/\mathcal {M}_{\odot })\gt 10.45$ and 〈tconvert〉 = 3.3 ± 0.3 and 〈tdelay〉 = 2.2 ± 0.4 Gyr for lower stellar mass galaxies. These quenching efficiencies and associated time-scales are used to rule out certain environmental mechanisms as being the primary processes responsible for transforming the star formation properties of galaxies over this 4 Gyr window in cosmic time.
Cosmological Evidence Modelling: a new simulation-based approach to constrain cosmology on non-linear scales
Authors: Lange Johannes U , van den Bosch Frank C , Zentner Andrew R , Wang Kuan , Hearin Andrew P , Guo Hong 
Published: September 2019

ABSTRACT
Extracting accurate cosmological information from galaxy–galaxy and galaxy–matter correlation functions on non-linear scales (${\lesssim } 10 \, h^{-1}{\rm {Mpc}}$) requires cosmological simulations. Additionally, one has to marginalize over several nuisance parameters of the galaxy–halo connection. However, the computational cost of such simulations prohibits naive implementations of stochastic posterior sampling methods like Markov chain Monte Carlo (MCMC) that would require of order $\mathcal {O}(10^6)$ samples in cosmological parameter space. Several groups have proposed surrogate models as a solution: a so-called emulator is trained to reproduce observables for a limited number of realizations in parameter space. Afterwards, this emulator is used as a surrogate model in an MCMC analysis. Here, we demonstrate a different method called Cosmological Evidence Modelling (CEM). First, for each simulation, we calculate the Bayesian evidence marginalized over the galaxy–halo connection by repeatedly populating the simulation with galaxies. We show that this Bayesian evidence is directly related to the posterior probability of cosmological parameters. Finally, we build a physically motivated model for how the evidence depends on cosmological parameters as sampled by the simulations. We demonstrate the feasibility of CEM by using simulations from the Aemulus simulation suite and forecasting cosmological constraints from BOSS CMASS measurements of redshift-space distortions. Our analysis includes exploration of how galaxy assembly bias affects cosmological inference. Overall, CEM has several potential advantages over the more common approach of emulating summary statistics, including the ability to easily marginalize over highly complex models of the galaxy–halo connection and greater accuracy, thereby reducing the number of simulations required.
Impact of the mean pressure profile of galaxy clusters on the cosmological constraints from the Planck tSZ power spectrum
Authors: Ruppin F , Mayet F , Macías-Pérez J F , Perotto L 
Published: September 2019

ABSTRACTCosmological analyses based on surveys of galaxy clusters observed through the Sunyaev–Zel’dovich (SZ) effect strongly rely on the mean pressure profile of the cluster population. A tension is currently observed between the cosmological constraints obtained from the analyses of the CMB primary anisotropies and those from cluster abundance in SZ surveys. This discrepancy may be explained by a wrong estimate of the hydrostatic bias parameter that links the hydrostatic mass to the true mass of galaxy clusters. However, a variation of both the amplitude and the shape of the mean pressure profile could also explain part of this tension. We analyse the effects of a modification of this profile on the constraints of the σ8 and Ωm parameters through the analysis of the SZ power spectrum measured by the Planck collaboration. We choose two mean pressure profiles that are respectively lower and higher than the one obtained from the observation of nearby clusters by Planck. The selection of the parameters of these two profiles is based on the current estimates of the pressure and gas mass fraction profile distributions at low redshift. The cosmological parameters found for these two profiles are significantly different from the ones obtained with the Planck pressure profile. We conclude that an ${\sim }15{{\ \rm per\ cent}}$ decrease of the amplitude of the mean normalized pressure profile would alleviate the tension observed between the constraints of σ8 and Ωm from the CMB and cluster analyses without requiring extreme values of the mass bias parameter.
Constraining spatial pattern of early activity of comet 67P/C–G with 3D modelling of the MIRO observations
Authors: Zhao Y , Rezac L , Hartogh P , Ji J , Marschall R , Keller H U 
Published: September 2019

ABSTRACT
Our aim is to investigate early activity (2014 July) of 67P/C–G with 3D coma and radiative transfer modeling of Microwave Instrument on the Rosetta Orbiter (MIRO) measurements, accounting for nucleus shape, illumination, and orientation of the comet. We investigate MIRO line shape information for spatial distribution of water activity on the nucleus during the onset of activity. During this period we show that MIRO line shape have enough information to clearly isolate contribution from ‘neck’ (Hapi) and bottom of large lobe (Imhotep), and compare it to the nominal case of activity from the entire illuminated surface. We also demonstrate that spectral line shapes differ from the 1D model for different viewing geometries and coma conditions relevant to this study. Specifically, line shapes are sensitive to the location of the terminator in the coma. At last, fitting the MIRO observations we show that the Imhotep region (possible distributed source of H2O sublimating from the icy grains in the coma lifted due to CO2 activities) contributes negligible fraction of the total number of water molecules into MIRO beam in the early activity. On the other hand, a strong enhancement of water activity from the ‘neck’ region seems required to fit the MIRO line shapes. This is consistent with earlier analysis of Rosetta results. Nevertheless, within the assumption of our coma and surface boundary conditions we cannot get a reasonable fit to all MIRO mapping observations in 2014 July. We provide discussion on how to enhance these results and resolve the found issues in the future.
Patterns of Genomic Differentiation in the Drosophila nasuta Species Complex
Authors: Mai Dat , Nalley Matthew J , Bachtrog Doris 
Published: September 2019

AbstractThe Drosophila nasuta species complex contains over a dozen recently diverged species that are distributed widely across South-East Asia, and which shows varying degrees of pre- and postzygotic isolation. Here, we assemble a high-quality genome for D. albomicans using single-molecule sequencing and chromatin conformation capture, and draft genomes for 11 additional species and 67 individuals across the clade, to infer the species phylogeny and patterns of genetic diversity in this group. Our assembly recovers entire chromosomes, and we date the origin of this radiation ∼2 Ma. Despite low levels of overall differentiation, most species or subspecies show clear clustering into their designated taxonomic groups using population genetics and phylogenetic methods. Local evolutionary history is heterogeneous across the genome, and differs between the autosomes and the X chromosome for species in the sulfurigaster subgroup, likely due to autosomal introgression. Our study establishes the nasuta species complex as a promising model system to further characterize the evolution of pre- and postzygotic isolation in this clade.
Stress-Driven Transposable Element De-repression Dynamics and Virulence Evolution in a Fungal Pathogen
Authors: Fouché Simone , Badet Thomas , Oggenfuss Ursula , Plissonneau Clémence , Francisco Carolina Sardinha , Croll Daniel 
Published: September 2019

Abstract
Transposable elements (TEs) are drivers of genome evolution and affect the expression landscape of the host genome. Stress is a major factor inducing TE activity; however, the regulatory mechanisms underlying de-repression are poorly understood. Plant pathogens are excellent models to dissect the impact of stress on TEs. The process of plant infection induces stress for the pathogen, and virulence factors (i.e., effectors) located in TE-rich regions become expressed. To dissect TE de-repression dynamics and contributions to virulence, we analyzed the TE expression landscape of four strains of the major wheat pathogen Zymoseptoria tritici. We experimentally exposed strains to nutrient starvation and host infection stress. Contrary to expectations, we show that the two distinct conditions induce the expression of different sets of TEs. In particular, the most highly expressed TEs, including miniature inverted-repeat transposable element and long terminal repeat-Gypsy element, show highly distinct de-repression across stress conditions. Both the genomic context of TEs and the genetic background stress (i.e., different strains harboring the same TEs) were major predictors of de-repression under stress. Gene expression profiles under stress varied significantly depending on the proximity to the closest TEs and genomic defenses against TEs were largely ineffective to prevent de-repression. Next, we analyzed the locus encoding the Avr3D1 effector. We show that the insertion and subsequent silencing of TEs in close proximity likely contributed to reduced expression and virulence on a specific wheat cultivar. The complexity of TE responsiveness to stress across genetic backgrounds and genomic locations demonstrates substantial intraspecific genetic variation to control TEs with consequences for virulence.
Probiotics and prebiotics: focus on psychiatric disorders – a systematic review
Authors: Barbosa Renata S D , Vieira-Coelho Maria A 
Published: September 2019

Abstract

Context
The gut-brain axis and microbial dysbiosis may play a role in psychiatric diseases. In this view, the gut microbiota has been considered a potential therapeutic target using probiotics and prebiotics.

Objective
This systematic review aims to find the existing clinical evidence that may justify the use of probiotics or prebiotics in psychiatric patients.

Data sources
PRISMA guidelines were followed for a systematic literature review of randomized controlled trials that assessed the effect of prebiotics or probiotics in patients diagnosed with a classified psychiatric disorder.

Data extraction
From a total of 212 studies screened, 11 were included in the final systematic review. Quality assessment of the included trials was assessed by the Jadad scale.

Results
Probiotics seem to offer some benefit in major depressive disorder and Alzheimer’s disease. One study showed that probiotics reduced rehospitalization in patients with acute mania. In autism spectrum disorders, the results were controversial; however a single study found that early administration of probiotics showed a preventive role. No benefits were found for patients with schizophrenia. In most studies, no major adverse effects were reported.

Conclusions
Although recent findings in specific psychiatric disorders are encouraging, the use of prebiotics and probiotics in clinical practice stills lacks sufficiently robust evidence.
Individual incentives and workers’ contracts: evidence from a field experiment
Authors: Choudhary M Ali , Gabriel Vasco J , Rickman Neil 
Published: September 2019

AbstractWe present evidence on the operation of incentive pay from a field experiment in Pakistan, looking at piece rates and pay based on rank achieved in a tournament. Importantly, some workers are in contracts ‘tying’ them to the employer for several picking seasons; others are ‘untied’, in the sense of being employed for only the current season. We find that incentive pay (of either type) improves productivity by 30%, on average, but that there are important differences across the types of workers: in particular, tournament incentives are less effective amongst the tied workers. We suggest that our main results have implications for tournament theory and the design of incentive pay schemes, particularly with regard to the fact that they may discourage some workers and, thus, reduce incentives.
Microsurgical Technique for Treatment of Perimedullary Spinal Arteriovenous Fistulae: 2-Dimensional Operative Video
Authors: Howard Brian M , Barrow Daniel L 
Published: September 2019

Abstract
The case is of a 49-yr-old female admitted after acute onset lower cervical/upper thoracic region pain with left hemi-body hypoesthesia below the C7 level. Magnetic resonance imaging showed a spinal cord intraparenchymal hemorrhage at the C6/7 levels. Physical exam revealed hypoesthesia on the left from C7 and below with associated 3/5 wrist and finger extensor and 4/5 triceps strength on the left. The remainder of the neurological exam was normal including lower extremity strength and bowel/bladder function. A craniocervical angiogram showed a perimedullary arteriovenous fistula on the left, ventrolateral aspect of the spinal cord with a single feeding artery that originated from the thyrocervical trunk and entered through the left C6 nerve root sleeve. Venous drainage was cephalad to cortical cerebellar veins and to the suboccipital plexus. A branch of the thyrocervical trunk supplying the ventral spinal cord originated close to the fistula, which precluded endovascular embolization. The patient underwent C6-T1 laminectomies for microsurgical treatment of the fistula. This case demonstrates multiple key concepts in the surgical management of these rare lesions as follows: the ventral aspect of the cervical spinal cord can be safely approached from posterior. The venous anatomy is often confusing and intraoperative angiography utilizing both indocyanine green and conventional digital subtraction techniques are of paramount importance. Unlike arteriovenous malformations, the venous drainage can be pruned to gain visualization and trace the venous anatomy retrograde to the point of the fistula. The patient awoke from surgery at her neurological baseline. The patient consented to de-identified publication of this case.
Productivity and Misallocation in General Equilibrium
Authors: Baqaee David Rezza , Farhi Emmanuel 
Published: September 2019

Abstract
This paper develops a general theory of aggregation in inefficient economies. We provide nonparametric formulas for aggregating microeconomic shocks in economies with distortions such as taxes, markups, frictions to resource reallocation, financial frictions, and nominal rigidities. We allow for arbitrary elasticities of substitution, returns to scale, factor mobility, and input-output network linkages. We show how to separately measure changes in technical and allocative efficiency. We also show how to compute the social cost of distortions. We pursue applications focusing on firm-level markups in the United States. We find that improvement in allocative efficiency, due to the reallocation over time of market share to high-markup firms, accounts for about half of aggregate TFP growth over the period 1997–2015. We also find that eliminating the misallocation resulting from the large and dispersed markups estimated in the data would raise aggregate TFP by about 15%, increasing the economy-wide cost of monopoly distortions by two orders of magnitude compared with the famous 0.1% estimate by Harberger (1954). These exact numbers should be interpreted with care because the data are imperfect and require substantial imputation.