bluuebunny/crossref_metadata_2025_split huggingface dataset:
Instructional technique questions in the evaluating stage of project based learning to improve concept map score
Authors: Arum Dwi Rahayu Yacinta , Widoretno Sri , Dwiastuti Sri , Sajidan  , Rinanto Yudi 
Published: June 2019

Abstract
The study aimed to improve student’s Concept map (CM) scores teacher’s questions on evaluating data, arriving a conclusion, presenting the project in class as preferred and discussion (evaluating data) stage of Project Based Learning. This research was a classroom action research with 3 Cycles. Procedure of this research are planning to compile the lesson plan, implementation of actions, observation, reflection, and construct expert concept map. The subject of this research consisted of 36 students of senior high school. The research data is the concept map score. Validation use triangulation method. verification of CM scores suitability and documentation based on CM experts and interviews. Data obtained by reducing data, graph transformation, and drawing conclusions. The result of this research showed that the teacher’s questions functioned as instructional techniques that improve the CM scores of students.
The Validity of Item Tests of Scientific Method of Divergent Patterns in Biology Subject at Senior High Schools Viewed From The Number of Traits
Authors: Nur Cahyani Fajar , Subali Bambang 
Published: June 2019

Abstract
The initial stage of the research was developing a blue print based on learning continuum, formulating divergent test item models, assigning two experts on measurement and one expert on biological education assessment for reviewing, and performing a try out in the field. The population in this research is the hypothetical population that have characteristics such as selected samples by selecting five Public Senior High Schools in Bantul Regency ranging from schools which have gained highest national examination score to that of the lowest which consist of 954 testee. The data were analyzed using the Quest program referring to the Partial Credit Model (PCM). The analysis was performed to determine the validity of test items which have been developed viewed from single, double, and triple trait. The results of the try out show that all items are fitted with PCM for single and double trait based on INFITMNSQ acceptance limits. Meanwhile, one item is not fitted with PCM for triple trait precisely the trait to investigate. When INFIT-t acceptance limit is employed, some items are not fitted. They include 10 items of single trait, 3 items of double trait precisely the trait to design and perform an investigation and 2 items of the trait to report the results of the investigation. In addition, the non-fitted items for triple trait consist of 3 items of the trait to design an investigation, 2 items of the trait to perform an investigation, and 2 items of the trait to report the results of the investigation.
Weighbridge vibration analysis using 3 accelerometer sensors and single excitation
Authors: Syafri  , Darman  
Published: June 2019

Abstract
Weighbridge was a measuring instrument that was widely used by the Ministry of Transportation to scale the weight of loaded vehicles on the roadways. Due to being traversed by vehicles with various kind of weight and sizes, weighbridges often experience resonance due to the vibrations of vehicles above it. This will potentially cause damages to weighbridges. To anticipate it, researches regarding vibration analysis on weighbridge were needed to decrease resonance on weighbridges. The Vibration Analysis was done by Modal Analysis Method using three accelerometers and one shaker as the measurement sensor. In testing, weighbridge was modeled into a cylindrical beam shape with a length of 724 mm and a diameter of 16 mm. As the supports, Fix-fix Support was used at both ends of the beam. Next, Accelerometer measurement sensor mounted in three positions with a distance of 181 mm, 362 mm, 543 mm from beam supports. Then, Excitation force with four frequency variations (1 Hz, 3 Hz, 5 Hz, 10 Hz) was applied to the four measuring points located between the accelerometer sensor. The measurements result in the form of FRF graph can be obtained by QuickDAQ. From the FRF graph, the five lowest natural frequency of the weighbridge was obtained that equal to 89.9 Hz, 91 Hz, 69.9 Hz, 75 Hz, and 96.9 Hz.
Study of stinging nettle fibers as a reinforcing of composite materials based on its growing region
Authors: Suryawan I G P A , Suardana N P G , Winaya I N S , Suyasa I W B , Lokantara I P 
Published: June 2019

Abstract
Stinging nettle is a perennial herbaceous plant belonging to the Urticaceae family, In Bali Indonesia called jelatang. This species is considered a weed in intensive agriculture as its fast vegetative growth and high densities enable increased spread and soil coverage. In Tabanan Bali Indonesia several places to grow are in Denbantas altitude 200-500 meters and in Bedugul altitude 1000 -1500 meters above sea level. Nettle fibers are natural fibers that can be utilized as reinforcement for composite materials. Natural fibers have been used worldwide as a potential replacement for glass fiber reinforced composites, over the last few years has been applied in the automotive sector, aircraft interior and interior of the building. Properties of the natural fiber is lighter, easier to handle, not abrasive, and low cost. The objective of this study was to compare the composition and the tensile strength of the fiber nettle based growing areas from Bedugul and Denbantas. The method used is a fiber tensile test equipment, fourier transformer infrared red (FTIR), thermo-gravimetric analysis (TGA) and scanning electron microscope (SEM). From the research of nettle fibers that stinging nettle from Denbantas has a better tensile strength than Bedugul nettle. The TGA test the visible fiber from Denbantas is superior when used as a composite reinforcement.
Observations of mechanical and manual forging on bronze as a gamelan material
Authors: Priambadi I G N , Sugita I K G 
Published: June 2019

Abstract
Gamelan is a traditional musical instrument used by Hindu Balinese in religious and cultural activities. The process of making gamelan begins with the manufacture of copper alloy composition (Cu) and lead (Sn), melting, casting, forging and tone forming by grinding on the surface of the blades. The process of forging on the manufacture of bronze gamelan (CuSn) with an open casting method absolutely must be done because the casting results tend to cause the occurrence of porosity. Porosity that occurs in the bronze as a gamelan material will affect the sound produced. The research conducted is to compare the results of manual forging and mechanical means, where the observations are made on the percentage of deformation that occurs, the density, the hardness and the microstructure of the bronze material. The observations show that mechanical forging provides better mechanical properties, deformation rates, and product microstructure.
Experimental study of an organic rankine cycle system using r134a as working fluid with helical evaporator and condenser
Authors: Martin A , Romy  , Agustina D , Ibra A M 
Published: June 2019

Abstract
Organic Rankine Cycle (ORC) system is a modification of the conventional Rankine cycle to generate electricity from the utilization of low-grade temperature heat sources. Experiment on ORC systems was conducted to analyse the performance of a small scale ORC system with 1 kW capacity using R134a as working fluid. A helical type of evaporator and condenser were used as heat exchangers and a scroll type car compressor was used to generate power with variation in heat source temperatures of 75°C, 85°C, and 95°C. Turbine power is calculated theoretically based on the experimental data obtained due to the turbine was not able to rotate. This experiment results show the optimum efficiency and theoretical power of ORC is respectively 3.33% and 279.58 Watt with inlet pressure and temperature of turbine are respectively 1.25 MPa and 67.7°C.
Design and manufacturing of organic rankine cycle (orc) system using working fluid r-134a with helical evaporator and condenser
Authors: Martin A , Romy  , Agustina D , Ibra A M 
Published: June 2019

Abstract
Waste heat from industries such as steam power plants can be utilized to meet the world’s electricity need. However, it cannot be converted efficiently to electric power by using conventional power generation methods as opposed to a technology called Organic Rankine Cycle (ORC). ORC is one of the power plant systems that is a modification of the Rankine Cycle using organic working fluid. In this research, ORC was designed and manufactured using R-134a as working fluid and helical heat exchanger as evaporator and condenser. The design of ORC systems based on simulation using Cycle Tempo 5.0 with evaporator temperature of 90°C, condenser temperature of 10°C, inlet pressure of pump of 0.55 MPa, and inlet pressure of turbine of 0.79 MPa. The results of this study showed the length of tube evaporator and condenser of 10.61 m and 10.56 m, respectively, with system efficiency achieved at 3.8%. Based on experiment, with evaporator temperature of 95°C, condenser temperature of 10°C, inlet pressure of pump of 0.48 MPa and inlet pressure of turbine of 0.52 MPa so resulted of system efficiency of 3.33%.
Thermal resistance analysis of central processing unit cooling system based on cascade straight heat pipe
Authors: Septiadi W N , Ula W A W , D Wulandari I G A A , Tnunay I A , Murti M R 
Published: June 2019

Abstract
The development of electronic device is moving toward Smart Technologies, But, the idea of Smart Technologies brings a new problem to heat flux management because the device produces more heat to be banished, especially CPU. So to solve those problems, heat pipe was chosen to be an alternative solution. Heat pipe was hoped to be a passive cooling system technology, but further research shows that goal can’t be achieved, due to the high condenser temperature, and the cooling system still needs fan support to banish the heat quickly from the device. So, this paper will discuss a research about new cascade system for heat pipe with variations of heat load and amount of condenser. The results were compared to non-cascade heat pipe to know its thermal performance, especially in thermal resistance. The results show that application of cascade straight heat pipe is effective to solve high condenser temperature problem. In thermal resistance, non-cascade heat pipe still better, but the differences only around 0.3-0.37 °C/W. For the comparison between single and double condenser, double condenser shows better thermal performance. In the end, this cascade heat pipe technology is effective to be applied for central processing unit cooling system technology.
Combinatorial diversity of Syk recruitment driven by its multivalent engagement with FcεRIγ
Authors: Travers Timothy , Kanagy William K. , Mansbach Rachael A. , Jhamba Elton , Cleyrat Cedric , Goldstein Byron , Lidke Diane S. , Wilson Bridget S. , Gnanakaran S. 
Published: June 2019

Syk/Zap70 family kinases are essential for signaling via multichain immune-recognition receptors such as tetrameric (αβγ2) FcεRI. Syk activation is generally attributed to cis binding of its tandem SH2 domains to dual phosphotyrosines within FcεRIγ-ITAMs (immunoreceptor tyrosine-based activation motifs). However, the mechanistic details of Syk docking on γ homodimers are unresolved. Here, we estimate that multivalent interactions for WT Syk improve cis-oriented binding by three orders of magnitude. We applied molecular dynamics (MD), hybrid MD/worm-like chain polymer modeling, and live cell imaging to evaluate relative binding and signaling output for all possible cis and trans Syk–FcεRIγ configurations. Syk binding is likely modulated during signaling by autophosphorylation on Y130 in interdomain A, since a Y130E phosphomimetic form of Syk is predicted to lead to reduced helicity of interdomain A and alter Syk’s bias for cis binding. Experiments in reconstituted γ-KO cells, whose γ subunits are linked by disulfide bonds, as well as in cells expressing monomeric ITAM or hemITAM γ-chimeras, support model predictions that short distances between γ ITAM pairs are required for trans docking. We propose that the full range of docking configurations improves signaling efficiency by expanding the combinatorial possibilities for Syk recruitment, particularly under conditions of incomplete ITAM phosphorylation.
The Impact of NuVal Shelf Nutrition Labels on Food Purchase
Authors: Zhen Chen , Zheng Xiaoyong 
Published: June 2019

AbstractSummary shelf nutrition labels are one of a handful of practical strategies that hold the promise of improving nutrition and public health. We use a difference‐in‐differences approach to estimate the effect of the NuVal shelf label—an interpretive numeric score, now defunct, that rated the overall nutrition of foods from one (least healthful) to 100 (most healthful)—on consumer demand for yogurt. The results indicate that NuVal labels affected product sales through an information provision effect that increases with the value of the nutrition score on the product and a publicity (i.e., salience) effect that is unrelated to the level of the score. A one‐point increase in NuVal score on a yogurt product is estimated to increase demand by 0.23%.
PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations
Authors: Kamat Mihir A , Blackshaw James A , Young Robin , Surendran Praveen , Burgess Stephen , Danesh John , Butterworth Adam S , Staley James R 
Published: June 2019

Abstract

Summary
PhenoScanner is a curated database of publicly available results from large-scale genetic association studies in humans. This online tool facilitates ‘phenome scans’, where genetic variants are cross-referenced for association with many phenotypes of different types. Here we present a major update of PhenoScanner (‘PhenoScanner V2’), including over 150 million genetic variants and more than 65 billion associations (compared to 350 million associations in PhenoScanner V1) with diseases and traits, gene expression, metabolite and protein levels, and epigenetic markers. The query options have been extended to include searches by genes, genomic regions and phenotypes, as well as for genetic variants. All variants are positionally annotated using the Variant Effect Predictor and the phenotypes are mapped to Experimental Factor Ontology terms. Linkage disequilibrium statistics from the 1000 Genomes project can be used to search for phenotype associations with proxy variants.

Availability and implementation
PhenoScanner V2 is available at www.phenoscanner.medschl.cam.ac.uk.
Multifocal origin of occupational cholangiocarcinoma revealed by comparison of multilesion mutational profiles
Authors: Mimaki Sachiyo , Watanabe Masahiko , Kinoshita Masahiko , Yamashita Riu , Haeno Hiroshi , Takemura Shigekazu , Tanaka Shogo , Marubashi Shigeru , Totsuka Yukari , Shibata Tatsuhiro , Nakagama Hitoshi , Ochiai Atsushi , Nakamori Shoji , Kubo Shoji , Tsuchihara Katsuya 
Published: June 2019

Abstract
Recently identified occupational cholangiocarcinoma among printing workers is characterized by chronic bile duct injuries and precancerous or early cancerous lesions at multiple sites of the bile ducts. These observations suggested the potential multifocal carcinogenesis of the disease. We performed whole-exome analysis of multiple lesions, including the invasive carcinomas and precancerous lesions of four occupational cholangiocarcinoma cases. A much higher mutation burden was observed in both the invasive carcinomas (mean 76.3/Mb) and precancerous lesions (mean 71.8/Mb) than in non-occupational cholangiocarcinomas (mean 1.6/Mb). Most somatic mutations identified in 11 of 16 lesions did not overlap with each other. In contrast, a unique trinucleotide mutational signature of GpCpY to GpTpY was shared among the lesions. These results suggest that most of these lesions are multiclonal in origin and that common mutagenic processes, which may be induced by exposure to haloalkanes or their metabolites, generated somatic mutations at different sites of the bile ducts. A similarly high mutation rate had already been identified in the precancerous lesions, implying an increased potential for carcinogenesis throughout the biliary tree. These genomic features support the importance of ongoing close follow-up of the patients as a group at high risk of recurrence.
Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies
Authors: Grabovac Igor , Veronese Nicola , Stefanac Sinisa , Haider Sandra , Jackson Sarah E , Koyanagi Ai , Meilinger Michael , Stubbs Brendon , Firth Joseph , Soysal Pinar , Di Gennaro Francesco , Demurtas Jacopo , McDermott Daragh T , Abbs Adam D , Yang Lin , Smith Lee 
Published: June 2019

Abstract

Background
Our aim was to assess both the credibility and strength of evidence arising from systematic reviews with meta-analyses of observational studies and physical health outcomes associated with human immunodeficiency virus (HIV) but not acquired immunodeficiency syndrome.

Methods
We performed an umbrella review of observational studies. Evidence was graded as convincing, highly suggestive, suggestive, weak, or nonsignificant.

Results
From 3413 studies returned, 20 were included, covering 55 health outcomes. Median number of participants was 18 743 (range 403–225 000 000). Overall, 45 (81.8%) of the 55 unique outcomes reported nominally significant summary results (P &lt; .05). Only 5 outcomes (9.0%; higher likelihood of presence of breathlessness, higher chronic obstructive pulmonary disease [COPD] prevalence, maternal sepsis, higher risk of anemia, and higher risk of all fractures among people living with HIV [PLWHIV]) showed suggestive evidence, with P values &lt; 10–3; only 3 (5.5%; higher prevalence of cough in cross-sectional studies, higher incidence of pregnancy-related mortality, and higher incidence of ischemic heart disease among PLWHIV in cohort studies) outcomes showed stronger evidence using a stringent P value (&lt;10–6). None of the unique outcomes presented convincing evidence (Class I), yet 3 outcomes presented highly suggestive evidence, 5 outcomes presented suggestive evidence, and 37 outcomes presented weak evidence.

Conclusions
Results show highly suggestive and suggestive evidence for HIV and the presence of a cough, COPD, ischemic heart disease, pregnancy-related mortality, maternal sepsis, and bone fractures. Public health policies should reflect and accommodate these changes, especially in light of the increases in the life expectancy and the incidence of comorbidities in this population.
Overlap of Pink-footed Shearwaters and central Chilean purse-seine fisheries: Implications for bycatch risk
Authors: Carle Ryan D , Felis Jonathan J , Vega Rodrigo , Beck Jessie , Adams Josh , López Verónica , Hodum Peter J , González Andrés , Colodro Valentina , Varela Tiare 
Published: June 2019

Abstract
Understanding susceptibility of seabirds to fisheries bycatch requires quantifying overlap of seabird at-sea habitat with fisheries’ distribution and effort. Pink-footed Shearwaters (Ardenna creatopus) are vulnerable seabirds that breed only in Chile. Recently, high rates of Pink-footed Shearwater bycatch (i.e. >1,500 observed mortalities 2015–2017) were documented by observers in central Chilean purse-seine fisheries. We present analysis of Pink-footed Shearwater at-sea movements and overlap with central Chilean purse-seine fleets targeting common sardine (Strangomera bentincki), Peruvian anchoveta (Engraulis ringens), and Chilean jack mackerel (Trachurus murphyi). To determine overlap during 2015–2017, we paired locations from 49 Pink-footed Shearwaters rearing nestlings at Isla Mocha, Chile, with locations and number of observed purse-seine sets in central Chile. Pink-footed Shearwaters typically visited waters ≤30 km offshore throughout central Chile. Foraging trip durations varied interannually, with longer trips in 2016, but all years revealed persistent foraging hotspots near Valdivia, the Gulf of Arauco, and Isla Mocha, Chile. Greatest overlap between Pink-footed Shearwaters and fisheries occurred with the sardine/anchoveta fleet near Valdivia (artisanal and industrial) and the Gulf of Arauco (artisanal); overlap with the jack mackerel fleet was minimal. Given Pink-footed Shearwater bycatch documented in these fisheries, this overlap may indicate risk of bycatch for these birds, although we did not directly quantify shearwater–fisheries interaction. Our results can inform further fishery monitoring efforts, as well as collaboration among scientists, managers, and fishers to identify, quantify, and reduce fisheries bycatch of Pink-footed Shearwaters within Chile and internationally.
Frontiers in positron emission tomography imaging of the vulnerable atherosclerotic plaque
Authors: MacAskill Mark G , Newby David E , Tavares Adriana A S 
Published: June 2019

AbstractRupture of vulnerable atherosclerotic plaques leading to an atherothrombotic event is the primary driver of myocardial infarction and stroke. The ability to detect non-invasively the presence and evolution of vulnerable plaques could have a huge impact on the future identification and management of atherosclerotic cardiovascular disease. Positron emission tomography (PET) imaging with an appropriate radiotracer has the potential to achieve this goal. This review will discuss the biological hallmarks of plaque vulnerability before going on to evaluate and to present PET imaging approaches which target these processes. The focus of this review will be on techniques beyond [18F]FDG imaging, some of which are clinically advanced, and others which are on the horizon. As inflammation is the primary driving force behind atherosclerotic plaque development, we will predominantly focus on approaches which either directly, or indirectly, target this process.
21 hands for playing: on resolving a puzzle from the ‘Krakow lute tablature’
Authors: Schöning Kateryna 
Published: June 2019

Abstract
The ‘Krakow lute tablature’ (c.1553–1592) is preserved among the little-explored collections of the Ivan Franco National University in Lviv, Ukraine. This article is devoted to the 21 unique hand drawings on the tablature folios. Did such illustrations have any significance for readers of tablature in the 16th century? Were the hand-signs intended to convey information about the pieces to which they were obviously assigned, or even about the manuscript as a whole? Were they of didactic importance, and do they relate to performance practice around 1550 in the Polish–Lithuanian region? Could they have been used to help with the memorization of pedagogical instructions, or were they perhaps entered alongside the tablature ‘just for fun’?