bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enyhe szövettani eltérések ellenére gyors progressziójú proliferativ glomerulonephritis monoklonális immunglobulin-G-depozitumokkal
Authors: Bajcsi Dóra , Constantinou Kypros , Krenács László , Barabás Zsolt , Molnár Szabolcs , Nyiraty Szabolcs , Ábrahám György , Iványi Béla 
Published: October 2018

Abstract: Proliferative glomerulonephritis with monoclonal immunoglobulin G (IgG) deposits is characterized by granular deposits of monoclonal IgG; histologically it has typically a membranoproliferative or endocapillary pattern, and seen electronmicroscopically there are dense deposits without substructure. Here, we present the case of a 62-year-old Caucasian woman who was admitted with rapidly progressive kidney failure. The patient’s status, the laboratory and imaging examinations did not support prerenal, postrenal and – among the intrinsic causes – vascular and tubulointerstitial origin. The proteinuria and dysmorphic microhematuria suggested rapidly progressive glomerulonephritis. Tests for anti-neutrophil cytoplasmic antibodies, anti-glomerular basement membrane, antinuclear antibodies and cryoglobulins were negative, the C3 and C4 levels were normal. The biopsy evaluation diagnosed proliferative glomerulonephritis with monoclonal IgG deposits because of mesangial granular deposits of IgG3-kappa, C3, and C1q, and ultrastructurally electron-dense deposits (incidence in our adult native kidney biopsy series: 0.18%). 31 glomeruli were assessed histologically. 29 glomeruli displayed mild mesangial hypercellularity, 2 glomeruli were globally sclerotic. Crescents were not observed. Mild arteriolar hyalinosis, interstitial fibrosis and tubular atrophy accompanied the glomerular alterations. In the postbiopsy evaluation, paraprotein or multiple myeloma was not detected. Despite the mild histological findings, the kidney failure progressed, and hemodialysis had to be started two weeks after the biopsy. Steroids, cyclophosphamide and rituximab did not affect her kidney function, and she remained on hemodialysis during the follow-up of 39 months. This report presents for the first time proliferative glomerulonephritis with monoclonal IgG deposits as the possible cause of rapidly progressive nephritic syndrome in the absence of pronounced glomerular proliferative, sclerotic or tubulointerstitial lesions. Orv Hetil. 2018; 159(38): 1567–1572.
Kezdeti tapasztalatok a 99mTc-PSMA-SPECT/CT-vel prosztatarákos betegekben
Authors: Farkas István , Besenyi Zsuzsanna , Maráz Anikó , Bajory Zoltán , Palkó András , Sipka Gábor , Pávics László 
Published: October 2018

Abstract: Introduction: The prostate-specific membrane antigen (PSMA) is a transmembrane protein, that is highly expressed on the surface of prostate cancer cells. In the last few years, several PSMA-specific ligands have been developed, that can be successfully used to detect primary prostate cancer, tumor recurrences and metastases as well. Aim: The goal of our work was to examine the clinical application of a 99mtechnetium-labeled PSMA-radiopharmaceutical as part of the routine diagnostics of prostate cancer. Method: We examined 15 male patients with verified prostate adenocarcinoma with suspicion of progression or recurrence of the disease. We performed whole-body PSMA-SPECT/CTs and multiparametric MRIs of the prostate and the pelvic regions within a week. We used 99mTc-mas3-y-nal-k(Sub-KuE) for the PSMA-SPECT scans. The images were visually evaluated by independent observers. The results were compared with the follow-up bone scintigraphies as well. Results: Twenty-two PSMA-positive lesions were found. Nine of them were localized outside, 13 were within the MRI’s field of view. From these 13 lesions, 7 matched with the SPECT/CT results and in 5 cases the MRI images showed no abnormalities. In one case, bone metastasis was suspected on the MRI scan but there was no corresponding pathological tracer uptake on the SPECT images. In two patients, none of the examinations showed signs of prostate malignancy. Four patients had PSMA-positive bone metastases. One of them had a matching PSMA/SPECT and bone scintigraphy result and in one case the PSMA examination showed metastasis in contrast to the negative bone scintigraphy. Conclusion: PSMA-SPECT/CT with 99mTc-mas3-y-nal-k(Sub-KuE) is a promising diagnostic tool. This technique is capable of visualizing bone metastases and it can detect local recurrences and visceral metastases as well. Orv Hetil. 2018; 159(35): 1433–1440.
Az állkapocsízületi károsodás kezelése szteroiddal, illetve hialuronsavval
Authors: Vingender Szonja , Restár László , Csomó Krisztián Benedek , Schmidt Péter , Hermann Péter , Vaszilkó Mihály 
Published: October 2018

Abstract: Introduction: Derangement of the temporomandibular joint complicates everyday life, due to the masticatory malfunction and the continuous pain sensation of the head and facial region. The therapy is multidisciplinary and varying. In case of the inefficiency of conservative therapy, minimally invasive intervention is needed with intraarticular injection. Aim: The aim of our study was to examine whether hyaluronic acid injection is more beneficial compared to corticosteroid in 37 joints. We also examined whether the efficacy of the therapy is influenced by hyaluronic acid molecular weight and the used protocol. Method: Wilkes stage, maximal mouth opening and the Visual Analogue Scale were determined pre-operatively and 6 months later. Corticosteroid application was performed once, hyaluronic acid was injected on a weekly bases 3 times in a row, by use of low (6–10 × 105 dalton) or high molecular weight (24–36 × 105 dalton) preparations. Results: The medical state of the patients treated with corticosteroid temporarily improved, but the symptoms returned. Due to hyaluronic acid treatment, significant improvement was revealed in all parameters (pwilkes<0.0001; pmouth-opening = 0.0002; pVAS<0.0001). There was no significant relapse (T = 2.05). The third administration of hyaluronic acid resulted in a significant improvement of the Visual Analogue Scale compared to the first and second injection (T3.–1. = 20.37; T3.–2. = 9.57). Conclusions: Comparing the two agents we can state that hyaluronic acid was significantly more effective and its application for three times seems to be the most effective treatment decreasing the symptoms. The high molecular weight solution was more effective in increasing mouth opening. In contrast to hyaluronic acid, corticosteroid had no prolonged effect in higher Wilkes stages. Orv Hetil. 2018; 159(36): 1475–1482.
A PET/MR képalkotás magyarországi klinikai alkalmazásának lehetőségei, első tapasztalatai
Authors: Tóth Zoltán , Lukács Gábor , Cselik Zsolt , Bajzik Gábor , Egyed Miklós , Vajda Zsolt , Borbély Katalin , Hadjiev Janaki , Gyarmati Tünde , Emri Miklós , Kovács Árpád , Repa Imre 
Published: October 2018

Abstract: Hungary’s first and still only multimodality PET/MR device is operating in the Health Center of Kaposvár University. The aim of our review article is to present the current Hungarian PET/MR imaging application opportunities, our available initial experiences with this novel multimodality imaging technique in malignant and non-malignant diseases and further potential targeted clinical fields of use are also addressed. Orv Hetil. 2018; 159(34): 1375–1384.
Meteorológiai paraméterek változásának hatása a halálos kimenetelű aortaaneurysma-rupturákra
Authors: Berczeli Márton , Szilágyi Brigitta , Lovas Attila , Pál Dániel , Oláh Zoltán , Törő Klára , Sótonyi Péter 
Published: October 2018

Abstract: Introduction: There are several statements about the connection between cardiovascular diseases and climate change. On behalf of our observation-based knowledge we hypothesized a relationship between the occurence of aortic aneurysm (AA) rupture and weather changes. Aim: The purpose of our study was to explore the relationship between fatal aortic catastrophe and changes in atmospheric pressure and temperature. By using a new method we could even measure the intensity of the connection. Method: We have developed a software earlier to examine the link between pulmonary embolism mortality and the weather on data sets comprised of aortic aneurysm cases, where the medical condition had led to the fatal rupture of the aorta. For the events mentioned earlier we used the autopsy database of Semmelweis University between January 1, 2005 and January 1, 2014. Altogether we examined 152 aneurysm-related aortic catastrophes. We reported the exact day of the incident and the weather conditions on that day and the day before. Results and conclusion: We have defined that the occurrence rate of fatal aortic catastrophe showed a slight dependence on the two examined parameters within our groups. We have found the connection related to ruptured aortic aneurysm and changes in atmospheric pressure more significant than their connection with mean daily temperatures. With the increase in atmospheric pressure, the rate of AA mortality also increased. In the knowledge of our results we believe that the mathematical model we used can be an effective starting point for population-based and prospective studies. Orv Hetil. 2018; 159(37): 1501–1505.
Sarcopenia és életminőség: a Sarcopenia Quality of Life (SarQoL) kérdőív hiteles magyar fordítása
Authors: Hodinka László , Vereckei Edit , Gasparik Andrea Ildikó 
Published: October 2018

Abstract: Introduction: Sarcopenia, or age-related muscle loss, is emerging as a serious public health concern. Due to the impaired physical performance associated with sarcopenia, a reduced quality of life (QoL) has been evidenced in the affected individuals. Generic instruments, such as Rand Corporation Short Form 36 (SF-36) or the European Quality of Life (EuroQoL-5D) questionnaires do not accurately assess the impact of sarcopenia on QoL. SarQoL (Sarcopenia Quality of Life) questionnaire, was the first disease-specific questionnaire addressing the quality of life in patients with sarcopenia and has been recently designed for providing a global assessment of the quality of life in community-dwelling elderly subjects aged 65 years and older. Aim: Our aim was the development of a valid Hungarian version of the original SarQoL, through the translation, cultural adaptation and content validation of the original questionnaire. Method: We followed the recommended process, the international protocol of translation in five steps: two initial translations, synthesis of the two translations, backward translation, expert committee to compare translations with the original questionnaire and pretest. The pretest process involved 20 subjects (10 clinically sarcopenic and 10 non-sarcopenic with different educational and socioeconomic backgrounds) who were asked to complete the questionnaire. Feedbacks were requested from all subjects regarding the comprehensibility of questions or difficulties in completing the test. Results: Using the recommended best practice protocol for translation, the pre-final version is comparable with the original instrument in terms of content and accuracy. Conclusion: After the content validation with clinically sarcopenic persons it should be a useful tool to assess the quality of life of people with sarcopenia among elderly Hungarian patients. Orv Hetil. 2018; 159(36): 1483–1486.
Újdonságok köszvényben: patogenezis, társbetegségek, diagnosztika és terápia
Authors: Soós Boglárka , Szamosi Szilvia , Benkő Szilvia , Paragh György , Szekanecz Zoltán 
Published: October 2018

Abstract: After a „silence” period for decades, a great body of new information has become available about the pathogenesis, diagnosis and treatment of gout. New data on purine metabolism and urate transporters have been published. It has become evident that gout is an autoinflammatory disease involving the inflammasome and interleukin-1. With respect to diagnosis, microscopic evaluation of the urate crystal is still the gold standard, however, sensitive imaging techniques (ultrasound, modern computed tomography methods) are able to visualize crystal deposition and tophus formation. Tophus size may also be monitored over time. We see a renaissance of non-pharmacological, lifestyle-related treatment modalities. Pharmacotherapy includes the resolution of attacks and urate-lowering maintenance therapy. In 2016, two recent series of recommendations have been published. Treat-to-target therapy aiming at urate levels ≤360 μmol/l is crucial. Urate-lowering therapy includes xanthine oxidase inhibitors (allopurinol, febuxostat). However, a number of novel compounds (urate transporter inhibitors, recombinant uricase, interleukin-1 inhibitors) are under development or before introduction to gout treatment. Comorbidites should be considered throughout the follow-up of gout patients. Orv Hetil. 2018; 159(40): 1625–1636.
Effects of saline irrigation water and proline applications on yield, vegetative and physiological characteristics of potato crop (Solanum tuberosum L.)
Authors: ÖDEMİŞ Berkant , BÜYÜKTAŞ Dursun , ÇALIŞKAN Mehmet Emin 
Published: October 2018

Potato
(Solanum tuberosum L.) is one of the most
important starch crops grown extensively. In this study, the effects of saline
water and proline content on yield and some characteristics of potato were
determined. Proline concentrations of 0 mM (control), 10 mM, and 20 mM were
applied to potato crop irrigated with water with electrical conductivities of
0.2 dSm-1 (control), 3.5 dSm-1, 7 dSm-1
10 dSm-1 and 13 dSm-1. Different levels of
saline irrigation water were obtained by adding NaCl into the tap water with an
EC of 0.2 dSm-1. In the saline water treatments, a leaching
fraction about 20% was applied. The
study was conducted between January-June 2010 in the pots located in a
greenhouse under the Eastern Mediterranean (Hatay, Turkey) conditions. Compared
to the control treatment, the amount of irrigation water and crop water use
decreased by 4.5%-18.9% and 3.0%-16.0% depending on soil salinity,
respectively. Soil salinity caused a decrease in total tuber yield, mean tuber
weight, total dry weight, harvest index, and number of potatoes classified as
Grade A, whereas it caused an increase in total dry matter content. No distinct
effects of proline on tuber yield were observed in the treatments of higher
salt stress. The effect of increasing proline concentration was mostly
pronounced in the vegetative and gas exchange parameters.
Aspectos psicossociais e intervenções realizadas com o adolescente depressivo: revisão integrativa nacional da última década
Authors: Lima Gerusa Marcondes Pimentel de Abreu , Mio João Vítor Rodrigues , Santos Graciella Navarros , Campos Claudinei José Gomes 
Published: October 2018

INTRODUÇÃO: Somente no inicio da década de 70 que a depressão na adolescência foi considerada uma doença, visto a considerar que este transtorno ocasiona danos e prejuízos considerados de alta complexidade. OBJETIVO: O objetivo do estudo foi analisar as produções cientificas da literatura brasileira na última década a fim de se aprofundar o conhecimento sobre o transtorno depressivo em adolescentes. MÉTODO: a presente investigação é uma revisão integrativa nacional, compreendida no ano de 2007 a 2016 integrados no seguintes banco de dados: Scielo, LILACS, Scopus, CINAHL, PUBMED, MEDLINE, PUBMED e BDEnf. A análise temática foi usada para a discussão dos 15 artigos encontrados. RESULTADOS: Os comportamentos negativos nas relações sociais, principalmente, depressão, ansiedade e agressividade, costumam ficar evidenciados em torno dos 11 a 16 anos de idade. CONSIDERAÇÕES FINAIS: O meio e a mídia social em que o adolescente está inserido é considerado um fator de impacto que reflete não somente no âmbito familiar, mas também, na escola e na sociedade em geral.
Reflexões psicanalíticas a respeito do vínculo materno na constituição do sujeito
Authors: Saruwatari Ana Alice Fugimoto , Gaviglia Vera Lucia , Antonio Camila de Araujo 
Published: October 2018

O presente trabalho possui por objetivo refletir acerca dos elementos que se apresentam no desenvolvimento do sujeito, caracterizando as relações parentais e sua implicação na formação do sujeito. Trata-se de um estudo de revisão de literatura com recortes teóricos psicanalíticos realizados por meio de livros e de textos clássicos da psicanálise, objetivando responder como as relações parentais, em especial o vínculo materno, contribuem para a constituição do sujeito e analisar a relevância de tal vínculo para diagnóstico e a prática clínica psicanalítica. O método empregado neste trabalho foi a pesquisa bibliográfica tendo como vertente a teoria psicanalítica, a qual norteou o trabalho. Os principais autores usados foram Sigmund Freud, Donald Winnicott e Julieta Jerunsalinsky. Este estudo se tornou relevante, pois discorre sobre a dinâmica envolvida na constituição do sujeito relacionando o desenvolvimento com as funções parentais. Na prática clínica é possível realizar a escuta dos significantes que constituem o sujeito ao longo do desenvolvimento e como consequência proporcionar a ressignificação dos conflitos decorrentes.
ТЕРМИЧЕСКОЕ ОКСИДИРОВАНИЕ КАК СПОСОБ СОЗДАНИЯ НАНОРАЗМЕРНЫХ ФУНКЦИОНАЛЬНЫХ ПЛЕНОК НА ПОЛУПРОВОДНИКАХ AIIIBV: ХЕМОСТИМУЛИРУЮЩЕЕ ВОЗДЕЙСТВИЕ ОКСИДОВ МЕТАЛЛОВ ОБЗОР
Authors: Tominа E. V. , Mittova I. Ya. , Sladkopevtsev B. V. , Kostryukov V. F. , Samsonov A. A. , Tretyakov N. N. 
Published: October 2018

Рассмотрены особенности хемостимулирующего воздействия оксидов металлов на процесс термооксидирования полупроводников AIIIBV. Установлено, что химическая природа оксида-хемостимулятора и способ его введения в систему (из газовой фазы или нанесение на поверхность полупроводника) определяют механизм процесса. Оксиды р-металлов (PbO, Sb2O3, Bi2O3) реализуют транзитный механизм оксидирования независимо от способа их введения в систему. Оксиды d-металлов (MnO2, V2O5, CrO3), вводимые через газовую фазу, выступают в роли хемостимуляторов-транзиторов. Воздействие наноразмерных слоев NiO и Co3O4 развивается по транзитному типу. Для нанесённых на поверхность полупроводника наноразмерных слоёв V2O5 механизм их воздействия на процесс оксидирования АIIIВV в значительной мере определяется методом нанесения (в рамках одного способа) – мягким или жёстким.

Результаты исследований получены на оборудовании Центра коллективного пользования Воронежского государственного университета. URL: http://ckp.vsu.ru
Работа выполнена при поддержке гранта РФФИ № 16-43-360595 р_а
Edição e sociabilidades intelectuais. A edição das obras completas de Rui Barbosa.
Authors: Couto Gabriela Albanás , Pinheiro Lucas Souza , Valle Ione Ribeiro 
Published: October 2018

Resenha da obra Edição e sociabilidades intelectuais. A edição das obras completas de Rui Barbosa, escrita pelo Prof. Dr. Luciano Mendes de Faria Filho, da Universidade Federal de Minas Gerais. A obra expressa o resultado de ampla pesquisa histórica e historiográfica, na qual o autor buscou, sobretudo, conhecer, a partir do movimento em torno da publicação das Obras Completas de Rui Barbosa, quais os intelectuais que mais se destacavam no país naquele momento e que redes de sociabilidade constituíam.FARIA FILHO, L. M. de. Edição e sociabilidades intelectuais. A edição das obras completas de Rui Barbosa. Belo Horizonte: Autêntica/Editora da UFMG, 2017. 299 p. R$ 54,90.
Pengaruh Produk Terhadap Keputusan Nasabah Perbankan Syariah (studi kasus Perbankan Syariah di Kota Palembang)
Authors: Lemiyana Lemiyana 
Published: October 2018

Penelitian ini dilakukan pada nasabah perbankan syari’ah di Kota Palembang.Penelitian ini bertujuan untuk menganalisis Pengaruh Produk Terhadap Keputusan Nasabah di Perbankan Syariah Kota Palembang. Populasi dalam penelitian ini adalah seluruhnasabah aktif pengguna layanan perbankan syariah di kota Palembang. Metodesampling yang digunakan dalam penelitian ini adalah teknik Sampling Aksidental sebanyak 160 responden. Metode analisis data menggunakan Metode Structural Equation Modelling (SEM). Dari hasil penelitian didapatkan kesimpulan bahwa Produk tidak berpengaruh signifikan terhadap keputusan Nasabah Perbankan Syariah.
Kata Kunci : Produk, Keputusan
PENGARUH METODE MIND MAPPING TERHADAP KEMAMPUAN PEMAHAMAN KONSEP MATEMATIS DAN MOTIVASI BELAJAR SISWA SMP NEGERI 5 PRABUMULIH
Authors: Agustin Dyah , Syahbana Ali , Paradesa Retni 
Published: October 2018

Penelitian ini bertujuan untuk mengetahui pengaruh metode mind mapping terhadap kemampuan pemahaman konsep matematis dan motivasi belajar siswa SMP Negeri 5 Prabumulih. Populasi penelitian ini sebanyak 8 kelas siswa kelas VIII SMP Negeri 5 Prabumulih. Sampel penelitian diambil sebanyak 2 kelas, satu kelas sebagai kelas eksperimen, sedangkan satu kelas lagi sebagai kelas kontrol. Kemampuan pemahaman konsep matematis dilihat dari nilai posttest dari soal tes sebanyak 5 butir. Untuk motivasi belajar siswa dilihat dari nilai angket motivasi belajar sebanyak 28 pernyataan. Teknik analisis data menggunakan uji dua pihak dilihat dari Independen Sample T-Test pada program SPSS Versi 23 For Windows. Hasil Penelitian menunjukkan bahwa terdapat pengaruh metode mind mapping terhadap kemampuan pemahaman konsep matematis dan terdapat pengaruh metode mind mapping terhadap motivasi belajar siswa SMP Negeri 5 Prabumulih.
RELIABILITAS INTER RATER INSTRUMEN TES MATEMATIKA MENGGUNAKAN RATER
Authors: Destiniar Destiniar 
Published: October 2018

Tujuan penelitian ini adalah untuk mengetahui adakah perbedaan koefisien reliabilitas inter rater soal tes matemtika yang dinilai oleh guru matematika SMP dan dosen pendidikan matematika. Rater yang digunakan pada penelitian ini terdiri dari 20 orang guru matematika SMP dan 20 orang dosen pendidikan matematika sedangkan instrument yang dinilai adalah instrument tes matematika kelas IX yang berbentuk pilihan ganda. Metode penelitian yang digunakan adalah eksperimen dan analisis data dilakukan dengan menggunakan statistic uji t. Hasil yang diperoleh tidak ada perbedaan koefisien reliabilitas inter rater soal tes matematika yang dinilai oleh guru matematika SMP dan dosen pendidikan matematika.
The Arctic ice melting confirms the new theory
Authors: Sartori Ernani 
Published: October 2018

AbstractThe new theory shows that the global and the Arctic atmospheres behave as an open atmosphere (few clouds) or as a ‘closed’ atmosphere (fully cloudy), which explains the Arctic ice melting. Within the closed atmosphere the solar radiation, wind and evaporation are reduced while the water and air temperatures and the humidity increase. Real data confirm these effects for the planet and for the Arctic. Many authors did not understand these apparent inconsistencies, but this paper solves many intriguing problems, and provides solutions that led the present author to discover the new hydrological cycle. Some human activities increase the formation of clouds and precipitation or of droughts. The sun is not the only heat source for the atmosphere. Several real data confirm that clouds have increased over decades globally and at the Arctic. These intensifications also confirm the operation of the new hydrological cycle and of the Sartori theory. Many real data show that while the Arctic ice has melted, the cloud cover has pushed the temperatures up above freezing and has raised them by 2–3 °C compared to cloudless skies as well as acting to warm the Arctic for most of the annual cycles.