bluuebunny/crossref_metadata_2025_split huggingface dataset:
Measurement and decomposition of education-related inequality in exclusive breastfeeding practice among Ethiopian mothers: applying Wagstaff decomposition analysis
Authors: Dessie Anteneh Mengist , Zemene Melkamu Aderajew , Gebeyehu Asaye Alamneh , Anley Denekew Tenaw , Anteneh Rahel Mulatie , Moges Natnael , Chanie Ermias Sisay , Tsega Sintayehu Simie , Belete Melaku Ashagrie , Alemayehu Ermiyas , Kebede Natnael 
Published: December 2024

BackgroundHuman breast milk, a naturally balanced source of infant nutrition, promotes optimal growth and health when exclusively fed for 6 months. Exclusive breastfeeding reduces common childhood infections, provides protection against some chronic illnesses, and contributes to achieving several Sustainable Development Goals. Despite its benefits, only 58% of Ethiopian women practice it, and the associated education-related inequality is not well documented. Thus, this study aims to quantify and decompose the education-related inequality in exclusive breastfeeding practice among Ethiopian mothers.MethodsA total of 1,504 weighted samples were studied using a Performance Monitoring for Action Ethiopia longitudinal panel survey dataset (2021–2023). Wagstaff normalized concentration index and its concentration curve were used to assess education-related inequality in exclusive breastfeeding practice. Wagstaff decomposition analysis was performed to decompose the concentration index and identify factors contributing to the observed education-related inequality. Significance was declared at p-value &lt;0.05.ResultsThe overall prevalence of exclusive breastfeeding among Ethiopian women was 57.29% (95% CI: 54.79, 59.80%), with a greater concentration found among women with lower levels of education. This indicates an inequality that favors less educated women (pro-less educated inequality), as demonstrated by the Wagstaff normalized concentration index of −0.058 (95% CI: −0.113, −0.002). Factors that made a significant contribution to the observed education-related inequality in exclusive breastfeeding practice were residence (18.80%), region (29.31%), place of birth (−7.38%), and the wantedness status of the indexed pregnancy (82.58%). The indexed pregnancy’s wantedness was made a more elastic (elasticity = 0.282) contribution.ConclusionThe study identified a small yet significant education-related inequality in exclusive breastfeeding, favoring less educated women. Hence, emphasis should be placed not only on educating women but also on healthy habits that they can leave behind when they learn. Residence, region, place of birth, and indexed pregnancy’s wantedness significantly contributed to the observed education-related inequality. The elasticity value for each factor suggests that policy changes addressing these factors could readily reduce the observed inequality.
Interventions to support the psychological empowerment of nurses: a scoping review
Authors: Huang Liebin , Liu Ming , Wang Xin , Hsu Meihua 
Published: December 2024

BackgroundEstablishing an empowering work environment is significantly contributing to nurse’s job satisfaction, performance, retention, and organizational success. This study aimed to conduct a scoping review to chart and synthesize current research on interventions to support nurses’ psychological empowerment.MethodsTen databases were searched, including PubMed/Medline, Web of Science, Scopus, Embase, EBSCOhost, Cochrane Library, CNKI, Wanfang, VIP, and OpenGrey, following the Joanna Briggs Institute’s methodology for scoping reviews. The search encompassed literature from its inception to 5 September 2024. The selection of studies followed predetermined inclusion and exclusion criteria. A manualized systematic quality assessment method was applied to the included studies, and the extracted data were charted using a series of tables.ResultsEleven studies were included. Seven studies reported the theoretical framework used. The interventions are all educational and are divided into two main sections: theoretical learning and applied practice. The duration of the interventions spanned a wide range of hours. The intervention format was based on offline training. The participants included both nurse managers and nurses. The evaluation measures were mostly multiple time points using the Spreitzer Psychological Empowerment Instrument. The interventions were generally effective, although some studies reported different results.ConclusionResearch on psychological empowerment interventions for nurses is still in the developmental phase, with preliminary evidence validating their positive effects. Future research should focus on conducting randomized controlled studies with larger sample sizes, selecting appropriate theoretical frameworks to design interventions, enriching the content and form of interventions, and strengthening evaluation measures to improve the quality of psychological empowerment interventions for nurses.Systematic review registrationOSF, https://doi.org/10.17605/OSF.IO/W7ZG6.
Clinical feasibility study of transcatheter edge-to-edge mitral valve repair in dogs with the canine V-Clamp device
Authors: Potter Brianna M. , Orton E. Christopher , Scansen Brian A. , Abbott-Johnson Katie M. , Visser Lance C. , Chi I-Jung B. , Ross Evan S. , Del Nero Bruna , Tantisuwat Lalida , Krause Ellen T. , Rezende Marlis L. , Mama Khursheed 
Published: December 2024

ObjectiveTo determine procedural feasibility, safety, and short-term efficacy in dogs with severe degenerative mitral regurgitation (MR) undergoing transcatheter edge-to-edge repair (TEER) with a canine-specific device.DesignProspective, single-arm (uncontrolled), single-institution clinical feasibility study.AnimalsFifty client-owned dogs with severe degenerative MR operated over a 28-month period.MethodsTEER was performed using the canine mitral V-Clamp via a transapical approach using transesophageal echocardiographic and fluoroscopic guidance. Indices of MR severity were determined by echocardiography the day before and 2 to 3 days after the procedure.ResultsProcedural feasibility was 96% based on delivery of at least one device in 48 of 50 dogs. There were no procedural deaths. Procedural safety was 96% based on survival to hospital discharge in 48 of 50 dogs. Euthanasia in 2 dogs prior to hospital discharge was due to damage of the mitral valve and worsened MR after the procedure. Device-related adverse event rate was 6.3% based on 3 events (single-leaflet device detachment, locking failure, locking failure with device embolization) in 59 implanted devices. All three events were nonfatal and successfully treated with a second device. Median regurgitant volume (mL/kg) decreased (p &lt; 0.001) from 2.3 [1.9, 3.1] to 1.1 [0.3, 1.8]. Median effective regurgitant orifice area (cm2/m2) decreased (p &lt; 0.001) from 0.60 [0.40, 0.80] to 0.25 [0.10, 0.50].Conclusion and clinical importanceInitial feasibility results support continued development of TEER as a procedurally feasible, relatively low-risk, and low morbidity treatment for degenerative MR in dogs. Operator experience and case selection are likely to be important components of success of this technique. Evidence of short-term efficacy is promising but needs to be verified with longer-term follow up.
Semisynthesis and Antitumour Evaluation of Natural Derivatives from ent-Kaurene ent-15α-Angeloyloxykaur-l6-en-3β-ol Isolated from Distichoselinum tenuifolium
Authors: Yasser Yass K. , Gil Daniel , Zentar Houda , Durán-Peña María Jesús , Prados-Lopez Belen , Juárez-Moreno Jorge , Botubol-Ares José Manuel , Haidour Ali , Sainz Juan , Fernández Antonio , Alvarez-Manzaneda Ramón , Chahboun Rachid , Reyes-Zurita Fernando J. 
Published: December 2024

Two natural ent-kaurene diterpenoids, ent-15α-angeloyloxykaur-16-en-3β-ol (7) and ent-15α-angeloyloxykaur-16-en-3β,9-diol (8), were extracted from the aerial parts of Distichoselinum tenuifolium, and six new derivatives were synthesised from compound (7). The antitumour properties of these natural and derivative ent-kaurenes (2, 7, 9–13) were evaluated in three cancer cell lines: HT29 (colon cancer), HepG2 (hepatocellular carcinoma), and B16-F10 (murine melanoma). Among them, the synthesised ent-kaurene (13) containing an exomethylene–cyclopentanone moiety showed the strongest antiproliferative effects in all cell lines tested, with significantly lower IC50 values around 2.5 μM. Compounds 13 and 12, together with their precursor (7), were selected for further comparative cytometric and microscopic analyses. Cell cycle studies revealed that derivatives 12 and 13 exhibited promising cytostatic activity by inducing selective G2/M phase arrest, particularly effective in HT29 and HepG2 cells. Conversely, precursor (7) showed no significant effect on B16-F10 cell cycle distribution. The Annexin V-FITC/PI double staining assay confirmed the robust apoptotic effects of compounds (7), 12 and 13, with compound 13 inducing up to 99% total apoptosis and exhibiting significant apoptotic activity in all cell lines tested. These apoptotic effects were closely linked to mitochondrial dysfunction, as evidenced by a marked loss of mitochondrial membrane potential and reduced Rh123 fluorescence in treated cells, thereby activating the intrinsic apoptotic pathway. These findings highlight the critical role of mitochondrial disruption in the cytotoxic mechanisms of these ent-kaurenes and underscore their potential as promising anticancer agents.
UPAYA MENINGKATKAN HASIL BELAJAR SISWA MATA PELAJARAN IPS TERPADU MELALUI MODEL PEMBELAJARAN MAKE A MATCH
Authors: Putra Tafonao Dedi , Lahagu Arianto 
Published: December 2024

Penelitian ini dilatar belakangi oleh masalah yang ditemukan di kelas yaitu: hasil belajar siswa pada mata pelajaran IPS Terpadu masih kategori kurang tuntas, siswa kurang aktif saat proses pembelajaran berlangsung, kemampuan untuk mengembangkan pola pikir dan kreativitas masih kurang, serta siswa kelihatan bosan dalam mengikuti proses pembelajaran. Penelitian ini bertujuan: (1) Untuk mengetahui proses pembelajaran melalui penerapan model pembelajaran make a match; dan (2) Untuk mengetahui peningkatan hasil belajar siswa mata pelajaran IPS Terpadu kelas VIII SMPTK Arastamar Awoni Lauso. Jenis penelitian ini adalah Penelitian Tindakan Kelas (Classroom Action Research) yang dilakukan di kelas dengan tujuan memperbaiki/ meningkatkan mutu praktik pembelajaran. Penelitian menunjukan pada lembar observasi guru pada siklus I diperoleh sebesar 55,00% tergolong cukup dan siklus II meningkat sebesar 89,37% tergolong baik.hasil lembar observasi siswa, aktivitas siswa mengalami peningkatan yakni siklus I sebesar 53,39% tergolong cukup dan pada siklus II meningkat sebesar 81,73% tergolong sangat baik; dan (2) Hasil belajar siswa pada mata pelajaran IPS Terpadu kelas VIII SMPTK Arastamar Awoni Lauso mengalami peningkatan, siklus I rata-rata hasil belajar siswa sebesar 68, tergolong baik dengan persentase ketuntasan sebesar 62,07% digolongkan cukup, dan pada siklus II meningkat dengan rata-rata hasil belajar siswa sebesar 80,17 tergolong sangat baik dengan persentase ketuntasan sebesar 100% tergolong sangat baik. Perolehan data tersebut diatas maka peneliti menyimpulkan bahwa ada peningkatan hasil belajar siswa mata pelajaran IPS Terpadu kelas VIII melalui penerapan model pembelajaran make a match di SMPTK Arastamar Awoni Lauso.
ANALISIS KESALAHAN SISWA DALAM MENYELESAIKAN SOAL LITERASI NUMERASI BERDASARKAN PROSEDUR NEWMAN’S ANALYSIS ERROR SERTA UPAYA PEMBERIAN SCAFFOLDING PADA SISWA KELAS V SD NEGERI 1 WONOSARI
Authors: Ayu Pramoda Wardhani Dyah , Oktiningrum Wuli , Wibowo Andi , Muslihasari Adzimatnur , Nurfianti Sinta 
Published: December 2024

Penelitian ini dilatarbelakangi oleh rendahnya kemampuan Literasi Numerasi masyarakat Indonesia dikarenakan adanya kesalahan dalam mengerjakan permasalahan matematika. Berdasarkan hasil observasi yang dilakukan di SD Negeri 1 Wonosari berupa wawancara terhadap guru kelas V, diperoleh informasi bahwa peserta didik seringkali melakukan kesalahan dalam pengerjaan soal numerasi dimana hampir 60% siswa tidak memahami maksud soal sehingga cenderung keliru dalam menyelesaikan soal. Observasi berikutnya dengan memberikan soal literasi numerasi dan diperoleh data banyak kesalahan yang dilakukan siswa baik dalam pemahaman soal maupun dalam proses penyelesaian jawaban. Hasil analisis jawaban siswa menunjukkan 3 siswa dari 16 siswa kelas V sudah menunjukkan kemampuan unggul. Tujuan penelitian ini menghasilkan kajian tentang kesalahan yang dilakukan siswa dalam menyelesaikan soal literasi numerasi sesuai tahapan Newman dan upaya mengurangi kesalahan tersebut dengan pemberian scaffolding. Penelitian ini menggunakan pendekatan kualitatif dengan desain penelitian deskriptif kualitatif. Pengumpulan data diperoleh dari hasil tes, wawancara dan dokumentasi. Subjek penelitian ini adalah 2 subjek dari kelompok tinggi, 2 subjek dari kelompok sedang, dan 2 subjek dari kelompok rendah. Pengelompokan ini berdasarkan pada skor tes kemampuan literasi numerasi yang diberikan kepada siswa kelas V SD Negeri 1 Wonosari. Hasil penelitian menunjukkan bahwa siswa dalam menyelesaikan soal literasi numerasi setelah scaffolding menunjukkan suatu peningkatan dimana siswa melakukan kesalahan yang lebih sedikit dibandingkan sebelum diberikan scaffolding. Adapun kesalahan setelah scaffolding oleh siswa dengan kelompok tinggi adalah pada tahap encoding. Kesalahan setelah scaffolding oleh siswa dengan kemampuan sedang adalah transformation, process skill dan encoding. Kesalahan setelah scaffolding oleh siswa dengan kemampuan rendah adalah transformation, process skill dan encoding.
MEDIA PERMAINAN ULAR TANGGA BERBASIS CERITA PAHLAWAN DAERAH SEBAGAI MEDIA UNTUK MENINGKATKAN MINAT BELAJAR PESERTA DIDIK PADA MATA PELAJARAN IPS
Authors: Chatarina Novianti , Mema Anselmus 
Published: December 2024

Penelitian ini termasuk Penelitian Tindakan Kelas (PTK). Teknik pengumpulan data menggunakan teknik observasi, angket, tes, dokumentasi, dan catatan lapangan. Data yang terkumpul dianalisis secara deskriptif kualitatif dan deskriptif kuantitatif. Hasil penelitian menunjukkan bahwa media permainan ular tangga dapat meningkatkan minat belajar dan hasil belajar. Hal ini dapat dilihat dari persentase observasi minat belajar peserta didik yang mencapai kategori cukup aktif dan sangat aktif, yaitu 51% pada siklus I menjadi 90% pada siklus II dan persentase angket minat belajar peserta didik yang mencapai kategori cukup berminat dan sangat berminat, yaitu 60% pada siklus I menjadi 85% pada siklus II. Hasil belajar juga mengalami peningkatan dari persentase ketuntasan klasikal yaitu 54% pada siklus I menjadi 100% pada siklus II. Pemilihan media pembelajaran hendaknya disesuaikan dengan kesiapan belajar peserta didik dan jenis materi yang diberikan Penggunaan media dalam kelompok dan mengandung unsur permainan akan membuat pembelajaran lebih bermakna bagi peserta didik
MAKNA WAWI API ARA PLANGAN DALAM PERKAWINAN ADAT DI DESA NEN BURA KECAMATAN DORENG KABUPATEN SIKKA
Authors: Hoban Nong , Nean Veronika , Laba Laurensius Moa 
Published: December 2024

Tujuan untuk mengetahui makna wawi api ara plangan dalam perkawinan adat di desa Nen Bura Kecamatan Doreng Kabupaten Sikka. Teori yang dipakai adalah teori “makna” yang digagas oleh Satyanada. Metode penelitian yang digunakana dalam metode penelitian kualitatif. Pendekatan penelitian yang digunakan pendekatan penelitian deskriptif kualitatif.Teknik pengumpulan data adalah wawancara,dokumentasi, dan observasi. Teknik analisis data yang digunakan dalam penelitian ini, yaitu: 1) redukasi data (data pencarian) 2) display data (penyajian data) 3) vertifikasi (kesimpulan ). Hasil penelitian menunjukkan bahwa masyarakat masih berpegang teguh kepada adat istadat, khususnya dalam perkawinan adat. Makna wawi api ara plangan sebagai berikut: makna religi, makna sosial, makna budaya. Makna religi tersirat doa-doa permohonan pada WujutTertinggi dan restu leluhur. Makna sosial mengatur relasi antara manusia dengan manusia, manusia dengan leluhurnya. Makna kebudayaan. Pelaksanaan wawi api ara plangan dimaknai secara budaya oleh masyarakat desa Nen Bura sebagai pengetahuan atau ajaran leluhur yang perlu di wariskan dan dipertahankan sebagai bentuk pertanggungjawaban masyarakat Nen Bura kepada amanat leluhurnya.
PENGARUH MODEL PROBLEM BASED LEARNING TERHADAP HASIL BELAJAR IPA PADA SISWA KELAS IV SD
Authors: Abdullah Adi Neneng , Lelu Maria Kristina 
Published: December 2024

Penelitian ini bertujuan untuk mengetahui pengaruh dari model Problem Based Learning(PBL) pada mata pelajaran IPA terhadap hasil belajar siswa kelas IV SDI Ratedosa, Kecamatan Aesesa,Kabupaten Nagekeo. Jenis penelitian yang digunakan adalah penelitian kuantitatif. Sampel dalam penelitian ini berjumlah 36 orang yang terdiri dari 20 orang kelas eksperimen dan 16 orang kelas kontrol. Data yang diambil dalam penelitian ini berupa nilai tes hasil belajar siswa yang diberikan berupa pilihan ganda sebanyak 30 soal. Analisis dilakukan dengan menggunakan uji hipotesis. Hasil analisis menunjukan bahwa terdapat pengaruh model problem based learning terhadap hasil belajar siswa kelas IV SDI Ratedosa pada materi bagian-bagian tubuh tumbuhan dan fungsinya,dengan perolehan hasil uji hipotesis data posttest siswa menggunakan uji t dengan taraf signifikansi 5% yang menunjukkan bahwa nilai Asymp. Sig. (2-tailed) < 0,05 (0,001 < 0,05). Dengan demikian, Ha diterima yang berarti terdapat pengaruh model problem based learning terhadap hasil belajar siswa. Model problem based learning ini dapat memberikan pengalaman belajar yang baik bagi siswa, karena siswa terlibat aktif yang dapat mengasah kemandirian belajar siswa, mengkomunikasikan pendapat mereka, serta kemampuan berpikir mereka. Selain itu, pembelajaran menggunakan model ini membuat siswa akan lebih paham dan ingat dengan materi yang dipelajari karena dikaitkan dengan fenomena sehari-hari dan budaya serta kebiasaan masyarakat setempat yang menjadikan pembelajaran lebih bermakna
Effectiveness of the quercetin use in patients with COVID-19 with concomitant type 2 diabetes mellitus
Authors: Tylishchak Zoriana , Pryshliak Oleksandra , Boichuk Oleksandr , Fedorov Sergiy , Protsyk Andrii , Kobryn Taras , Miziuk Ruslan 
Published: December 2024

AimTo conduct a comparative analysis of the effectiveness of basic therapy and basic therapy with the inclusion of quercetin in patients with COVID-19 with concomitant type 2 diabetes.Material and methodsThere were examined 60 patients with COVID-19 with concomitant T2DM. Upon admission into the hospital and again after 10 days, serum levels of interleukin-6, C-reactive protein, procalcitonin, ferritin, endothelin-1 were determined, and capillaroscopy of the nail plate was performed. Patients of the group I (30) against the background of protocol therapy received 0.5 g of quercetin intravenously once a day for 10 days. Patients of the group II (30) received to basic therapy.ResultsAfter the treatment in patients of the group I general weakness decreased, body temperature normalized, improved saturation indicators, the level of acute-phase parameters (interleukin-6, CRP and ferritin) significantly decreased, a positive effect of quercetin on the level of D-dimer in blood serum was noted, indices of pericapillary edema and hemosiderin deposition significantly decreased, indices diameter of the arterial part of the capillary and capillary network density significantly increased.ConclusionsThe use of quercetin against the background of basic therapy in patients with COVID-19 and concomitant T2DM reliably reduces the level of acute-phase indices, has an important clinical significance for reducing endothelial dysfunction and for preventing thrombotic complications.
Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation
Authors: Lee Mu-Hsien , Lin Cheng-Hui , Wu Chi-Huan , Tsou Yung-Kuan , Sung Kai-Feng , Wang Sheng-Fu , Liu Nai-Jen 
Published: December 2024

BACKGROUND
Needle-knife precut papillotomy (NKP) is typically performed freehand. However, it remains unclear whether pancreatic stent (PS) placement can improve the outcomes of NKP.
AIM
To explore whether PS placement improves the success rate of NKP in patients with difficult biliary cannulation.
METHODS
This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary cannulation. In cases with incidental pancreatic duct cannulation during conventional biliary cannulation, the decision for pre-NKP PS placement was made at the endoscopist's discretion. The primary outcome was the difference in the NKP success rate between patients with and without PS placement; the secondary outcome was the adverse event rate.
RESULTS
Among the 190 participants, 82 received pre-NKP PS (PS-NKP group) whereas 108 did not [freehand or freehand NKP (FH-NKP) group]. Post-NKP selective biliary cannulation was successful in 167 (87.9%) patients, and the PS-NKP had a significantly higher success rate than the FH-NKP group (93.9% vs 83.3%, P = 0.027). The overall adverse event rates were 7.3% and 11.1% in the PS-NKP and FH-NKP groups, respectively (P = 0.493). A periampullary diverticulum (PAD) and significant intraoperative bleeding during NKP were independently associated with NKP failure; however, a pre-NKP PS was the only predictor of NKP success. Among the 44 participants with PADs, the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group (87.5% and 65%, respectively; P = 0.076).
CONCLUSION
PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.
Pembelajaran Karakteristik Grafik Fungsi dan Perubahannya Akibat Transformasi F^2 (X), 1/(F(x)), Dan |F(x)| Menggunakan Geogebra
Authors: Latifah Rizka Azizatul 
Published: December 2024

Keterampilan abad 21 atau keterampilan 4C (critical thinking and problem solving, communication, collaboration, creative and innovative) sangat dibutuhkan untuk bertahan menghadapi era revolusi industri 4.0. Keterampilan tersebut dapat dilatih melalui pembelajaran. Oleh karena itu, perlu adanya pembiasaan untuk melatih keterampilan tersebut pada proses pembelajaran, salah satunya melalui pembelajaran matematika. Kegiatan menganalisis dapat menjadi cara untuk mengasah keterampilan berpikir peserta didik. Salah satu materi yang memerlukan kegiatan analisis adalah karakteristik grafik fungsi dan perubahannya akibat transformasi. Tujuan dari penulisan artikel ini yakni untuk menjelaskan bagaimana pembelajaran karakteristik fungsi dan perubahannya akibat transformasi , , dan dengan memanfaatkan Geogebra serta korelasinya terhadap peningkatan keterampilan 4C. Metode dalam penulisan artikel adalah kajian literatur. Pada kegiatan analisis grafik tersebut perlu adanya media pembelajaran yang dapat digunakan untuk mempermudah proses pembelajaran. Media yang untuk pembelajaran grafik fungsi adalah Geogebra. Geogebra merupakan software yang dapat memvisualisasikan objek matematika seperti grafik fungsi. Penggunaan Geogebra dalam pembelajaran juga dapat digunakan untuk membiasakan keterampilan berpikir kritis, berpikir kreatif, berkolaborasi, dan berkomunikasi.