bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of structure and properties of antibacterial vascular patch used in abdominal aorta aneurysm surgeries
Authors: Draczyński Zbigniew , Gąsiorowski Tomasz , Kolesińska Beata , Boguń Maciej , Sujka Witold 
Published: June 2019

Background: Biocompatible materials are used for treatment of blood circulatory system diseases, especially abdominal aortic aneurysms. The most popular and often used are knitted and polymer vascular patches. The aim of this study was to optimize the manufacturing process of implantable materials, ensuring antibacterial activity useful for treating abdominal aorta aneurysms. Methods: The vascular patch was manufactured from Trevira® yarn. The parameters of the intermediate product and vascular patch were tested according to standard procedures. Results: The vascular patch, manufactured from microsilver-containing yarn, with crimps on the surface of the patch, has been found useful for treatment of abdominal aorta aneurysms. Introducing crimps on the surface of the patch resulted in reduction of water permeability and enabled cutting of the graft at various angles without fraying at the cut ends of the biomaterial. The final vascular patch was marked by a gradual release of silver within 48 hours. Conclusions: On the basis of the performed test, it has been demonstrated that an implantable material for the treatment of abdominal aorta aneurysms was obtained, and that it can be considered as an alternative for currently used vascular patches. The final vascular patch was marked by a gradual release of silver during the first period of incubation. The antibacterial properties of the final product were confirmed by observation of a significant reduction in the number of Staphylococcus aureus and Klebsiella pneumoniae bacterial colonies.
Restoration of an ancient temple mural by a local search algorithm of an adaptive sample block
Authors: Cao Jianfang , Li Yanfei , Zhang Qi , Cui Hongyan 
Published: June 2019

Abstract
Long-term influences in the external environment, including light, temperature and humidity, have caused varying degrees of damage to ancient Chinese murals. Allowing people to appreciate the original style of the murals has become important to experts, and the development of image processing and machine learning technology has allowed intelligent restoration of ancient murals. This paper proposed the adaptive sample block and local search (ASB–LS) algorithm based on the Criminisi algorithm to address the flaking deterioration of Kaihua Temple murals from the Song Dynasty. ASB–LS achieved virtual restoration of damaged areas. First, the mural’s compositional characteristics were analyzed, the structure tensor was introduced, and the data items were redefined using eigenvalues to ensure accurate transmission of the image’s structural information. Then, the data item was used to form a new priority function to improve the image filling order. Finally, the sample block size was adaptively selected by the average correlation of the structure tensor, and a local search strategy was used to improve matching efficiency, which effectively avoided mispropagation of the restored image structure and blinded search of the matching block. Experiments were performed on the Song Dynasty murals in the Kaihua Temple for two types of deterioration: flaking deterioration and artificial destruction. Compared with the Criminisi algorithm and two improved algorithms, the proposed ASB–LS algorithm had better subjective analysis and objective evaluation. Subjective visuals significantly improved and conformed to the image’s compositional characteristics, and the inpainting time efficiency improved, establishing a good foundation for restoring ancient murals.
Menin Associates With the Mitotic Spindle and Is Important for Cell Division
Authors: Sawicki Mark P , Gholkar Ankur A , Torres Jorge Z 
Published: June 2019

AbstractMenin is the protein mutated in patients with multiple endocrine neoplasia type 1 (MEN1) syndrome and their corresponding sporadic tumor counterparts. We have found that menin functions in promoting proper cell division. Here, we show that menin localizes to the mitotic spindle poles and the mitotic spindle during early mitosis and to the intercellular bridge microtubules during cytokinesis in HeLa cells. In our study, menin depletion led to defects in spindle assembly and chromosome congression during early mitosis, lagging chromosomes during anaphase, defective cytokinesis, multinucleated interphase cells, and cell death. In addition, pharmacological inhibition of the menin-MLL1 interaction also led to similar cell division defects. These results indicate that menin and the menin-MLL1 interaction are important for proper cell division. These results highlight a function for menin in cell division and aid our understanding of how mutation and misregulation of menin promotes tumorigenesis.
Self-Replication of Chiral α-Amino Acids in Strecker-Type Synthesis via Asymmetric Induction and Amplification of Their Own Chiral Intermediate α-Aminonitriles
Authors: Aiba Shohei , Tanaka Yudai , Tokunaga Yuji , Kawasaki Tsuneomi 
Published: June 2019

Abstract
Self-replication is one of the essential characteristics of life, therefore, chemical reaction, in which biologically related chiral enantioenriched compounds can promote their own production, is an attractive challenge in broad scientific fields. Here, we found asymmetric Strecker-type synthesis, in which chiral l- and d-α-amino acids enantioselectively induced the formation and amplification of their own chiral intermediates l- and d-α-aminonitriles in solid state, respectively. Thus, after the hydrolysis of aminonitriles, enantioenriched amino acids with the same structure and the same absolute configuration as that of the original compounds could be replicatively produced with improvement of enantiomeric excess. Following our first report on the replication of α-(p-tolyl)glycine, here we found that the enantiomer of α-(1-naphthyl)glycine and α-(o-tolyl)glycine can also replicatively multiply in the Strecker-type synthesis via the amplification of the corresponding aminonitriles. From the viewpoint of the absolute asymmetric Strecker-type amino acid synthesis, spontaneous formation, amplification and multiplication, i.e., enantioselective reactive crystallization of α-aminonitriles will be discussed.
Distribution of Toxoplasma gondii IgM and IgG antibody seropositivity among age groups and gestational periods in pregnant women
Authors: Sadiqui Shahida , Shah Syed Rafiq Hussain , Almugadam Babiker Saad , Shakeela Qismat , Ahmad Shehzad 
Published: June 2019

Background: Toxoplasmosis is a globally distributed parasitic disease. The present study aimed to estimate the prevalence and geographic distribution of toxoplasmosis as well as determine the percentage of toxoplasmosis-associated IgM and IgG seropositivity among different age groups. In addition, it aimed to estimate the proportion of toxoplasma IgM seropositivity among pregnancy trimesters. Methods: A total of 500 pregnant women were included in this study. From each participant, a 5-ml venous blood sample was collected and centrifuged to obtain serum that was tested for Toxoplasma gondii IgM and IgG antibodies using immunochromatographic testing and ELISA. Results: The overall seroprevalence of toxoplasmosis was 24.8%. Out of the total of 500 participants, only 8% had a serological marker of acute toxoplasmosis). There is a statistically significant difference in the seroprevalence of disease among the study areas. Amongst positive cases of every trimester, 54.34% of first trimester positive cases had a serologic marker for acute toxoplasmosis. Conclusions: In this study, there is a high prevalence of toxoplasmosis. Therefore, it is necessary to test every pregnant woman for toxoplasmosis and distinguish the type of infection, as well as the conduction of public health education programs to generate the awareness.
Characterisation of blood vessels used for coronary artery bypass surgery
Authors: Garnizone Marika , Vārtiņa Edīte , Pilmane Māra 
Published: June 2019

Saphenous veins are commonly used as coronary artery bypass grafts. Therefore, it is important to understand the vein wall morphology used for the bypass grafts.
Methods. Ten specimens of saphenous veins were obtained from 10 patients admitted to the Heart Surgery Centre of P. Stradiņš Clinical University Hospital for coronary artery bypass surgery and a histopathological study was conducted. The slides were processed for histological routine and immunohistochemical staining with following markers: endothelin (ET), metallomembranoproteinase 2 (MMP2), tissue inhibitor of metalloproteinase 2 (TIMP2), transforming growth factor beta (TGF β), hepatocyte growth factor (HGF), vascular endothelial growth factor (VEGF), protein gene product 9.5 (PGP9.5), vascular cell adhesion molecule (VCAM), intercellular adhesion molecule (ICAM). For the analysis of the positive structures detected by immunohistochemistry, a semiquantitative evaluation method was used.
Results. Normal histoarchitecture of the vein wall was evaluated by routine staining. Moderate positive endothelin containing endothelial cells and moderate to numerous positive VEGF cells were found on small blood vessels. Moderate positive MMP2 structures and variable – mainly moderate to numerous positive TIMP structures – were found in vein wall. Positive structures were evaluated as equal with both MMP2 and TIMP, with one exception where MMP2 positive structures were evaluated as moderate, but TIMP positive structures as few. All specimens were rich in TGFβ, VCAM and ICAM cells. Abundance of VCAM and ICAM positive endothelial cells was also found. Few HGF positive structures were found in tunica intima and few PGP9.5 positive nerve fibres in tunica adventitia.
Conclusions. Rich expression of TGFβ, VCAM, ICAM is characteristic for saphenous vein. A number of VEGF, MMP and TIMP positive cells found in saphenous vein wall indicates a presence of tissue remodelling and ischemia, while low number of HGF positive cells shows its lesser involvement in homeostasis regulation.
Characterization of morphology in healthy, traumatized and aged knee meniscus of different species: A pilot study
Authors: Podļesnaja Marija , Pilmane Mara , Ciems Modris 
Published: June 2019

Meniscus is a fibrocartilaginous anatomical structure that realizes complicated biomechanical functions in the knee joint. However, no comparative morphology studies have been done on different species and conditions regarding the meniscus. Thus, the aim of our pilot study was to compare the morphology of traumatized and aged human and healthy deer meniscus to reveal the tissue ground, growth, degeneration, cell death and inflammation factors.
The study included surgery materials from one deer and two humans. Biotin-streptavidin immunohistochemistry was performed for detection of tissue TGFβ1, MMP2, MMP9, collagen I, caspase, Il-1, Il-6, Il-10. The results were evaluated semiquantitatively. An abundant number of Collagen I positive cells were detected in the disordered human meniscus but not in the deer one. TGFβ1 was seen in numerous to abundant number of cells in all the three cases. MMPs and caspase were distributed with numerous to abundant cells in both human and deer meniscus. Numerous to abundant cells of traumatized and aged human menisci showed IL-1 and IL-6, while the deer meniscus demonstrated cytokine expression in a moderate number of cells only in limited zones. The traumatized human meniscus possessed an abundant number of IL-10 positive cells, while the deer and the aged human meniscus showed mainly a moderate number of IL-10 cells with some elevation of cytokine in superficial and deepest layers of the meniscus.
Pertumbuhan dan produksi tanaman kailan (Brassica oleracea) akibat pemberian mulsa jerami padi dengan takaran yang berbeda
Authors: Setiyaningrum Alvianisa Anjanuari , Darmawati Adriani , Budiyanto Susilo 
Published: June 2019

ABSTRACT The objective of this research was to examine the effect and quantity of rice straw mulch on the growth and production of kailan. This research was conducted inAspakusa Makmur Farms Association, Teras, Boyolali and Laboratory of Ecology and Plant Production, Faculty of Animal and Agricultural Sciences, Diponegoro University, Semarangfrom January 24th to March24th 2018. The research was assigned in completely randomized monofactor design with the factor was M0: control, M1: 2 ton/ha, M2: 4 ton/ha, M3: 6 ton/ha and M4: 8 ton/ha. Parameters observed were plant height, number of leaves, soil and temperature, plant and root wet weight, plant and root dry weight and total chlorophyll content.The results showed thatmulch treatment with a dose of 6 tons/ha was able to increase the yield of leaves, root dry weight and total chlorophyll content but did not increase crop yields, soil and temperature, plant and root wet weight, plant dry weight Keyword: Kailan, Mulch, Rice straw ABSTRAK Penelitian bertujuan untuk mengkaji pengaruh dan takaran mulsa jerami padi terhadap pertumbuhan dan produksi tanaman kailan. Penelitian dilakukan pada tanggal24 Januari 2018 – 24 Maret 2018 di Lahan pertanian Asosiasi Aspakusa Makmur Kecamatan Teras Kabupaten Boyolali dan Laboratorium Ekologi dan Produksi Tanaman, Fakultas Peternakan dan Pertanian, Universitas Diponegoro, Semarang. Penelitian disusun dengan rancangan acak lengkap monofaktor dengan perlakuan M0: kontrol, M1: jerami padi 2 ton/ha, M2: jerami padi 4 ton/ha, M3: jerami padi 6 ton/ha dan M4: jerami padi 8 ton/ha. Parameter yang diamati adalah tinggi tanaman, jumlah daun, kelembaban dan suhu tanah, berat basah tanaman dan akar, berat kering tanaman dan akar dan kandungan klorofil total. Hasil penelitian menunjukkan bahwa Perlakuan mulsa dengan takaran 6 ton/ha mampu meningkatkan hasil jumlah daun, berat kering akar dan kandungan klorofil total tetapi tidak meningkatkan hasil tinggi tanaman, kelembaban dan suhu tanah, berat basah tanaman dan akar, berat kering tanaman Kata kunci: kailan, mulsa, jerami padi
Pricing, Signalling, and Sorting with Frictions
Authors: Godenhielm Mats , Kultti Klaus , Virkola Tuomo 
Published: June 2019

Abstract
We analyse signalling and sorting in a market with frictions and private information. Buyers are heterogeneous, the sellers choose what quality to produce and post prices. Buyers do not observe quality, but infer it from prices. In equilibrium high-quality sellers signal quality with a price that is higher than under perfect information. Compared to the outcome under perfect information the higher price has two effects. First, it makes production of high-quality goods more attractive increasing its supply. Second, it makes high-valuation buyers worse-off, directing part of them to low-quality sellers. We determine which effect dominates; whether too many or too few sellers produce high quality. We also show that the prices of both high- and low-quality goods are higher, and the sellers do better and the buyers worse under private information. In addition, we show that an increase in the production cost of high quality may lead to higher profits and prices.
Optimization of a Computer Simulated Styrene Plant by Surface Response and Environmental Impact Evaluation
Authors: Vieira Goncalves Ricardo , Teixeira Gustavo , Torres Alice , de Assis Adilson Jose 
Published: June 2019

Abstract
Computer Aided Design of Chemical Process is now a well established eld in the design of new process as well as in the optimization, revamp and retrot of existing ones. The use of powerful process simulators available today allows the process engineer to simulate even an entire process, but the majority of process simulators have only classical unit operations. So, if the process has a non-classical unit operation it needs to be simulated using a suitable computer language and further to be linked to the simulator. In this paper we addressed the problem of including a new unit operation in a process simulator and how to use the virtual plant to optimize and to evaluate the environmental impact of a chemical process. We used the free chemical process simulator COCO to simulate two styrene process production plant. The firrst one uses as a reactor a conventional PFR that is available in the simulator. The second plant uses a membrane reactor that was simulated using the software Scilab that was embedded in COCO simulator by using the CAPE-OPEN protocol. Then, we used both virtual plants to develop meta-models of the processes by using experimental design and surface responses. These empirical models were used after to optimize the plants and the results shown that it is possible to increase the styrene productivity up to 27.32 kmol/h using a PFR reactor and up to 30.56 kmol/h using a membrane reactor. Finally, we calculated the Potential of Environmental Impact (PEI) for each process using the WAR algorithm and we shown that both processes have PEI very similar. Therefore, the route that uses membrane reactor has an advantage over the route that uses PFR reactor since it allows to obtain higher styrene productivities.
Aquatic Matter: Water in Victorian Fiction
Authors: Kluwick Ursula 
Published: June 2019

Abstract
This essay looks at water in Victorian fiction and argues that it is important not just as motif or symbol—which is how literary criticism has traditionally approached it—but as a metamorphic substance. I propose a material ecocritical framework in order to conceptualise water as literary matter, and I analyse selected passages from four canonical Victorian novels through a focus on aquatic materialisation and transformation. I argue that through the emphasis on these processes in a variety of water scenes from Jane Eyre, Wuthering Heights, Lady Audley’s Secret, and Dracula, water emerges as not inert but agential. Through a material ecocritical approach which rejects intentionality as a precondition of agency, representations of nature as animate can be reconceived as not necessarily anthropomorphic or as instances of the pathetic fallacy, but as bearing witness to how agency is shared by humans and their environment.
Detection of Sesame Oil Adulteration Using Low-Field Nuclear Magnetic Resonance and Chemometrics
Authors: Wang Ruiying , Liu Kangjing , Wang Xiaoling , Tan Mingqian 
Published: June 2019

Abstract
Identification of edible oil adulteration is an essential task for oil quality control. In this study, the adulteration of sesame oil samples with soybean oil was detected by low-field nuclear magnetic resonance (LF-NMR) combining with chemometrics including principal component analysis (PCA), partial least squares (PLS) and principal component regression (PCR) methods. PCA analysis was applied for the classification of various adulteration ratios of sesame oil samples. PLS and PCR were used for the detection of adulteration ratios of sesame oil samples. A calibration data set was established and evaluated by a cross-validation method. The correlation coefficients between actual and predicted values for the calibration and validation data sets were 0.953 and 0.973 for PLS and 0.975 and 0.979 for PCR, respectively. Therefore, a combination of LF-NMR with chemometrics can be applied for detecting sesame oil adulteration in a fast and nondestructive manner.
Numerical Simulation for Radiated Flow in Rotating Channel with Homogeneous-Heterogeneous Reactions
Authors: Hayat Tasawar , Ullah Ikram , Alsaedi Ahmed , Alsulami Hamed 
Published: June 2019

Abstract
The present work models MHD three-dimensional flow in a rotating channel. The energy expression is characterized by heat generation/absorption and radiation effects. Homogeneous-heterogeneous features are also accounted for. The obtained non-dimensional systems are numerically computed via the NDSolve based Shooting technique. Graphs are plotted to visualize the impact of various influential variables on velocity, temperature and concentration. In addition, skin friction and the Nusselt number are numerically estimated. Here temperature increases for increasing estimations of heat generation/absorption and radiation parameters. Furthermore, skin friction is reduced in the case of large Reynold number and rotation parameter.
Crystal structure of (3E,5E)-3,5-bis(3-nitrobenzylidene)-1-((4-(trifluoromethyl)phenyl)sulfonyl)piperidin-4-one — dichloromethane (2/1), C53H38Cl2F6N6O14S2
Authors: Sun Yue , Wang Shu-Xia , Hou Gui-Ge 
Published: June 2019

Abstract
C53H38Cl2F6N6O14S2, triclinic, P1̄ (no. 2), a = 12.1975(6) Å, b = 13.9973(7) Å, c = 16.3818(10) Å, α = 69.365(5)°, β = 76.620(5)°, γ = 77.292(4)°, V = 2516.8(3) Å3, Z = 2, R
gt(F) = 0.0540, wR
ref(F
2) = 0.1413, T = 100.02(10) K.
Humans, Animals, Things and Animacy
Authors: Bayanati Shiva , Toivonen Ida 
Published: June 2019

AbstractAnimacy influences the patterns of subject-verb agreement marking in many languages, including Persian and Inari Saami. In Persian, animate plural subjects trigger plural agreement on the verb, whereas inanimate subjects may or may not trigger agreement. The variation is governed by factors such as personification, agency and distributivity. In Inari Saami, verbs fully agree with human subjects and verbs partially agree with inanimate subjects. Verbs may or may not agree with subjects referring to animals. We argue that the intricate interaction between biological animacy and grammatical agreement in these two languages warrants careful consideration of the tripartite distinction between biological animacy in the world, our conceptualization of animacy and formal animacy features in the grammar.
Design, synthesis and characterization of hydroxyapatite-chitosan nanocomposite radiolabelled with 153Sm as radiopharmaceutical for use in radiosynovectomy
Authors: Attar Nosrati Sima , Alizadeh Robabeh , Ahmadi Seyed Javad , Erfani Mostafa 
Published: June 2019

Abstract
The aim of the present study was to introduction of hydroxyapatite/chitosan nanocomposite as a new radiosynovectomy agent with excellent properties. In this work, the nanocomposite was prepared through a reliable method and characterized using different techniques to elucidate its chemical structure and physiochemical properties. The prepared nanocomposite was successfully radiolabeled with 153Sm under optimal conditions and with high radiolabelling yield (99 %). The radiochemical purity of the prepared radiopharmaceutical was found to be >99 % as determined by ITLC technique. In vitro stability studies in saline solution and in human serum showed that the radiolabeled nanocomposite retained its stability for at least 6 days. The biodistribution and imaging studies in wild-type rats revealed high retention of the agent into the synovial joints of the knee even at 96 h post-injection, thereby indicating excellent in vivo stability of 153Sm labeled hydroxyapatite-chitosan nanocomposite. Therefore, the prepared radiopharmaceutical would be a potential therapeutic agent for use in radiosynovectomy procedure.