bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ambivalence, anxieties / Adaptations, advances: Conceptual History and International Law
Authors: CLARK MARTIN 
Published: September 2018

AbstractScholars of the history of international law have recently begun to wonder whether their work is predominantly about law or history. The questions we ask – about materials, contexts and movements – all raise intractable problems of historiography. Yet, few scholars have turned to historical theory to think through how we might go about addressing them.This article works towards remedying that gap by exploring why and how we might engage with historiography more deeply.Section 2 shows how the last three decades of the ‘turn to history’ can be usefully read as a move from ambivalence to anxiety. The major works of the 2000s thoroughly removed the pre-1990s ambivalence to history, offering brief considerations about method. Recent efforts building on those works have led to the present era of anxiety about both history and method, raising questions around materials, contexts and movements. But far from a negative state, this moment of anxiety is both appropriate and potentially creative: it prompts us to rethink our mode of engaging with historiography.Section 3 explores how this engagement might proceed. It reconstructs the principles and debates within conceptual history around the anxieties of materials, contexts and movements. It then explores how these might be adapted to histories of international law, both generally and within one concrete project: a conceptual history of recognition in the writings of British jurists.Section 4 concludes by considering the advances achieved by this kind of engagement, and reflects on new directions for international law and its histories.
Towards a Postcolonial Genealogy of International Organizations Law
Authors: SINCLAIR GUY FITI 
Published: September 2018

AbstractThis article sketches the contours of a postcolonial genealogy of international organizations law. Contrary to conventional accounts, which remain strongly Eurocentric, the article claims that international organizations law did not emerge until the closing stages of the Second World War, and that its evolution was strongly influenced by the accelerating processes of decolonization that accompanied its birth. More specifically, the article argues that the emergence of international organizations law was spurred by a series of perceived problems regarding the adequacy of the international legal system in the aftermath of the end of formal colonial rule, in which the relations of power constructed through colonialism remained profoundly implicated. The politics of decolonization thus shaped the practice of international organizations, provided the catalyst for many of the foundational cases in international organizations law, and motivated much of its early doctrinal scholarship. Moreover, the article argues that the functionalist logic of international organizations law is deeply embedded in a postcolonial imaginary which, by supporting the division of the world into formally equivalent nation-states, ostensibly cuts against the hegemonic territorialism of colonial governance.
Stability of aqueous formaldehyde under γ irradiation: prebiotic relevance
Authors: López-Islas A. , Colín-García M. , Negrón-Mendoza A. 
Published: September 2018

AbstractFormaldehyde is a precursor of sugars, which are compounds essential in all forms of life and a necessary molecule for prebiotic processes. This work focuses on evaluating the stability of formaldehyde exposed to a high radiation field simulating prebiotic conditions on primitive Earth, such as the ocean or shallow waters. Formaldehyde may have been formed from reactions in the atmosphere and from rainout processes reached water bodies. In our experiments, we employed γ radiation and found that formaldehyde was labile towards radiation and decomposed even at low irradiation doses due to the fact that aldehyde/hydrate groups present in formaldehyde structure are very reactive under irradiation. However, after exposing this molecule to several doses of irradiation, we detected the formation of formic acid and glycolaldehyde – both of which are of prebiotic interest. We also observed formaldehyde regeneration by one of its radiolytic products: formic acid.
Extractable and Germinable Seedbank Methods Provide Different Quantifications of Weed Communities
Authors: Reinhardt Theresa , Leon Ramon G. 
Published: September 2018

AbstractSeedbank sampling and quantification methods vary in their ability to describe weed diversity and density, so proper method selection is critical for studying weed communities. The germinable seedbank (GSB) method is commonly preferred over extractable seedbank method (ESB), because the latter is more time-consuming. However, these two methods have only been compared using a few weed species and a relatively small number of samples. A total of 204 weed seedbank samples were used to compare both methods for weed density, richness, evenness, and Shannon-Weiner diversity using a split-sample approach. The two methods yielded dramatically different results. The ESB had 418% higher density and 35% more species per sample but 11% less evenness than the GSB. Diversity was estimated to be only 9% higher using the extractable compared with the germinable method. While the extractable method had higher density and richness overall, this was not true for every species, with only 7 of 14 common species detected in higher amounts by the extractable method. The results indicate the two methods are not strongly correlated, limiting the possibility of generating a conversion factor between methods. Nevertheless, evenness and Shannon-Weiner diversity might allow comparisons between both methods when the emphasis is on characterizing predominant weed species. The GSB is a practical approach to compare treatments or conditions; however, the ESB is more useful to accurately quantify weed species richness, diversity, and density.
Limited Role of Working Time Shift in Offsetting the Increasing Occupational‐Health Cost of Heat Exposure
Authors: Takakura Jun'ya , Fujimori Shinichiro , Takahashi Kiyoshi , Hasegawa Tomoko , Honda Yasushi , Hanasaki Naota , Hijioka Yasuaki , Masui Toshihiko 
Published: September 2018

AbstractClimate change increases workers' exposure to heat stress. To prevent heat‐related illnesses, according to occupational‐health recommendations, labor capacity must be reduced. However, this preventive measure is expected to be costly, and the costs are likely to rise as the scale and scope of climate change impacts increase over time. Shifting the start of the working day to earlier in the morning could be an effective adaptation measure for avoiding the impacts of labor capacity reduction. However, the plausibility and efficacy of such an intervention have never been quantitatively assessed. Here we investigate whether working time shifts can offset the economic impacts of labor capacity reduction due to climate change. Incorporating a temporally (1 hr) and spatially (0.5° × 0.5°) high‐resolution heat exposure index into an integrated assessment model, we calculated the working time shift necessary to offset labor capacity reduction and economic loss under hypothetical with‐ and without‐realistic‐adaptation scenarios. The results of a normative scenario analysis indicated that a global average shift of 5.7 (4.0–6.1) hours is required, assuming extreme climate conditions in the 2090s. Although a realistic (<3 hr) shift nearly halves the economic cost, a substantial cost corresponding to 1.6% (1.0–2.4%) of global total gross domestic product is expected to remain. In contrast, if stringent climate‐change mitigation is achieved, a realistic shift limits the remaining cost to 0.14% (0.12–0.47%) of global total gross domestic product. Although shifting working time is shown to be effective as an adaptation measure, climate‐change mitigation remains indispensable to minimize the impact.
Variation in Plasmaspheric Hiss Wave Power With Plasma Density
Authors: Malaspina David M. , Ripoll Jean‐Francois , Chu Xiangning , Hospodarsky George , Wygant John 
Published: September 2018

AbstractPlasmaspheric hiss waves are commonly observed in the inner magnetosphere. These waves efficiently scatter electrons, facilitating their precipitation into the atmosphere. Predictive inner magnetosphere simulations often model hiss waves using parameterized empirical maps of observed hiss power. These maps nearly always include parameterization by magnetic L value. In this work, data from the Van Allen Probes are used to compare variation in hiss wave power with variation in both L value and cold plasma density. It is found that for L> 2.5, plasmaspheric hiss wave power increases with plasma density. For L> 3, this increase is stronger and occurs regardless of L value and for all local times. This result suggests that the current paradigm for parameterizing hiss wave power in many magnetospheric simulations may need to be revisited and that a new parameterization in terms of plasma density rather than L value should be explored.
Eolianite Grain Size Distributions as a Proxy for Large Changes in Planetary Atmospheric Density
Authors: Goosmann Erik A. , Catling David C. , Som Sanjoy M. , Altermann Wladyslaw , Buick Roger 
Published: September 2018

AbstractAtmospheres are dynamic over geologic timescales, making large changes in planetary air density possible. For the Earth, geological proxies suggest that air density in the Neoarchean was similar to or lower than today. This air density variation possibly affected eolian dune grain sizes by controlling the trajectories of grains though the air. Balancing the fall velocity and threshold friction velocity, a metric separating saltation and suspension transport, suggests that a lower air density could increase the mean grain size of dunes because decreased air drag extends the size range of grains in modified saltation and incipient suspension regimes. Consequently, the dune‐forming sand left behind in pure saltation, the dominant dune‐forming transport mode, could have coarser grains. We analyzed size distributions of two eolianites from 2.64 and 1.5 Ga (billion years ago) for deviations from modern sand dunes emplaced at sea level, which globally exhibit similar mean grain sizes. Both aeolianites have mean grain sizes within one standard deviation of the modern mean and are not statistically separable at 95% confidence. Overall, this suggests that while air density is important in eolian physics, a factor of 2 to 4 change in density is insufficient to produce an unambiguous grain size signal. This suggests that while eolian dune grain sizes have not significantly changed over the range of Earth's atmospheric conditions, they could be useful when investigating the order of magnitude changes thought to have occurred on Mars.
Thinning Can Reduce Losses in Carbon Use Efficiency and Carbon Stocks in Managed Forests Under Warmer Climate
Authors: Collalti Alessio , Trotta Carlo , Keenan Trevor F. , Ibrom Andreas , Bond‐Lamberty Ben , Grote Ruediger , Vicca Sara , Reyer Christopher P. O. , Migliavacca Mirco , Veroustraete Frank , Anav Alessandro , Campioli Matteo , Scoccimarro Enrico , Šigut Ladislav , Grieco Elisa , Cescatti Alessandro , Matteucci Giorgio 
Published: September 2018

AbstractForest carbon use efficiency (CUE, the ratio of net to gross primary productivity) represents the fraction of photosynthesis that is not used for plant respiration. Although important, it is often neglected in climate change impact analyses. Here we assess the potential impact of thinning on projected carbon cycle dynamics and implications for forest CUE and its components (i.e., gross and net primary productivity and plant respiration), as well as on forest biomass production. Using a detailed process‐based forest ecosystem model forced by climate outputs of five Earth System Models under four representative climate scenarios, we investigate the sensitivity of the projected future changes in the autotrophic carbon budget of three representative European forests. We focus on changes in CUE and carbon stocks as a result of warming, rising atmospheric CO2 concentration, and forest thinning. Results show that autotrophic carbon sequestration decreases with forest development, and the decrease is faster with warming and in unthinned forests. This suggests that the combined impacts of climate change and changing CO2 concentrations lead the forests to grow faster, mature earlier, and also die younger. In addition, we show that under future climate conditions, forest thinning could mitigate the decrease in CUE, increase carbon allocation into more recalcitrant woody pools, and reduce physiological‐climate‐induced mortality risks. Altogether, our results show that thinning can improve the efficacy of forest‐based mitigation strategies and should be carefully considered within a portfolio of mitigation options.
Multiscale Framework for Modeling Multicomponent Reactive Transport in Stream Corridors
Authors: Painter S. L. 
Published: September 2018

AbstractTravel time‐based representations of transport, a highly successful strategy for modeling conservative tracer transport in stream corridors, are extended to accommodate multicomponent reactive transport. Specifically, convolution representations used to model exchange of solute with the hyporheic zone are shown to be equivalent to solving one‐dimensional subgrid models in Lagrangian form coupled to the advection dispersion equation for the stream channel. Unlike the convolution‐based representations of previous travel time‐based stream transport models, the subgrid model generalizes to include multicomponent reactive transport with general nonlinear reactions. An example involving biomass growth, the establishment of redox zonation, and the resulting impact on denitrification rates demonstrate reach‐scale application of the new approach. Although simplified, those example simulations show some of the key phenomena associated with hyporheic zone denitrification that are not represented with conventional first‐order estimates.
Climate Controls on Runoff and Low Flows in Mountain Catchments of Western North America
Authors: Dierauer Jennifer R. , Whitfield Paul H. , Allen Diana M. 
Published: September 2018

AbstractIn the mountainous regions of western North America, snowmelt recharges groundwater and provides ecosystem‐sustaining base flow during low‐flow periods. Continued warming is expected to have large impacts on snowmelt hydrology and on low‐flow regimes, but the relative impact of temperature and precipitation on low flows is unclear. To address this knowledge gap, the dominant climate controls on summer and winter season low flows in 63 near‐natural catchments in mountainous ecoregions of western North America are identified with correlation analysis, and low‐flow sensitivity to temperature and precipitation is quantified with multiple linear regression analysis. Results show that precipitation is the dominant control on the interannual variability of annual runoff and on the duration and severity of summer and winter low flows. The temperature sensitivity of low flows, however, can be as much as twice that of annual runoff. Warm winters correspond to significantly lower runoff; significantly longer, more severe summer low flows; and significantly shorter winter low flows. This highlights the importance of winter climate conditions for runoff and low flows in these mountain catchments and provides another line of evidence regarding the impacts of climate change on snowmelt hydrology.
Identifying Wetland Consolidation Using Remote Sensing in the North Dakota Prairie Pothole Region
Authors: Krapu Christopher , Kumar Mukesh , Borsuk Mark 
Published: September 2018

AbstractArtificial drainage of wetlands in the Great Plains has been linked to increased runoff, erosion, and the consolidation of small, seasonal wetlands into larger, more permanent bodies of water. We analyzed hydrologic changes to over 1.2 million water bodies across the entire North Dakota portion of the Prairie Pothole Region using the ratio of aggregate water area and total perimetric length in a landscape‐scale shape index calculated from existing Landsat derived data of water presence/absence. This ratio showed a clear change point toward more consolidation of wetlands around the period 1999 (±1 year) after an extended multiyear period of above‐average rainfall. We used hydrologic simulations with forcing data from across the region to show that this shift is unlikely to be due solely to natural variation in precipitation and evapotranspiration. Using county‐level regressions, we found that wetland consolidation as measured by the shape index was highly correlated with agricultural transitions out of wheat and into corn and soybeans over the period 1984–2014 (R2 > 0.4), though we do not find evidence of a strong correlation between reported drainage and wetland consolidation. These results highlight a potential hysteretic interaction involving interannual variations in hydrologic forcing and anthropogenic landscape alterations on wetland consolidation in the North Dakota prairie potholes.
Effects of Forest Roads on Runoff Initiation in Low‐Order Ephemeral Streams
Authors: Ramos‐Scharrón C. E. , LaFevor M. C. 
Published: September 2018

AbstractUnderstanding hydrologic connectivity is essential for managing ephemeral headwater streams where upstream land use influences downstream aquatic habitats. This study relies on a field‐based approach to evaluate how precipitation and roads affect runoff generation in low‐order ephemeral streams of the U.S. Virgin Islands. Logistic regression analyses show that runoff delivery from unroaded catchments agrees with a water storage conceptual model typical for subsurface storm and saturation overland flow‐dominated settings. Without roads, runoff occurs only about 4 times per year in response to 10 and 78 mm of storm rainfall, depending on antecedent precipitation. In contrast, maximum 15‐min rainfall intensities are a better predictor of runoff generation on unpaved roads than are total rainfall and antecedent conditions. Intensities surpassing ~10 mm/hr lead to road runoff, and this occurs about 40 times per year. Road‐influenced streams represent an intermediate setting for which runoff generation depends on storm and antecedent rainfall, as well as the road surface area captured by drains and flow path distance. In our focus area, roads can provoke streams to deliver runoff to coral bearing waters 10 to 13 times every year as a response to 9.3‐ to 50‐mm storms, depending on antecedent rainfall and road drain characteristics. These results highlight the sensitivity of road connectivity to specific road drain characteristics and display the potential for connectivity as a guiding watershed restoration principle.
The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration
Authors: Dollt Claudia , Michel Julia , Kloss Loreen , Melchers Susanne , Schledzewski Kai , Becker Kathrin , Sauer Andrea , Krewer Andreas , Koll Franziska , Schmieder Astrid 
Published: September 2018

AbstractMelanoma is a highly immunogenic tumor with a good response to treatment with immune checkpoint inhibitors. Tumor-associated macrophages (TAMs) play an important immunosuppressive role in such tumors and have therefore been identified as possible future therapeutic targets in oncology. The aim of this study was to identify novel immunoregulatory receptors specifically expressed on TAM. Expression of Slamf9, a member of the signaling lymphocytic-activating molecule (Slam) immunoreceptor family, was found to be upregulated in a gene expression analysis of murine bone marrow-derived macrophages (BMDM) stimulated with tumor-conditioned medium of B16F1 melanoma cells. SLAMF9+ macrophages were identified in human and murine melanomas by using self-generated antibodies against human and murine SLAMF9. A comprehensive immunohistochemical analysis of tissue microarrays detected SLAMF9+ TAM in 73.3% of human melanomas, but also in 95.5% of naevi of melanoma patients and in 50% of naevi from healthy controls. In addition, 20% of melanomas and 2.3% of naevi from melanoma patients displayed a positive SLAMF9 expression also in melanocytic cells. No SLAMF9 expression was detected in naevus cells of healthy donors. Although SLAMF9 has no intracellular signaling motif, a comprehensive functional analysis revealed that the molecule was able to significantly enhance TNF-α secretion after LPS-stimulation. In addition, SLAMF9 delayed the wound closure of RAW 264.7 cells in a scratch assay, while proliferation and cell death were not affected. Taken together, SLAMF9 is a novel type-I-transmembrane receptor with immunomodulatory properties in macrophages. Further studies are required to evaluate whether SLAMF9 classifies as a promising future therapeutic target in melanoma.
Loss of PRC1 induces higher-order opening of Hox loci independently of transcription during Drosophila embryogenesis
Authors: Cheutin Thierry , Cavalli Giacomo 
Published: September 2018

AbstractPolycomb-group proteins are conserved chromatin factors that maintain the silencing of key developmental genes, notably the Hox gene clusters, outside of their expression domains. Depletion of Polycomb repressive complex 1 (PRC1) proteins typically results in chromatin unfolding, as well as ectopic transcription. To disentangle these two phenomena, here we analyze the temporal function of two PRC1 proteins, Polyhomeotic (Ph) and Polycomb (Pc), on Hox gene clusters during Drosophila embryogenesis. We show that the absence of Ph or Pc affects the higher-order chromatin folding of Hox clusters prior to ectopic Hox gene transcription, demonstrating that PRC1 primary function during early embryogenesis is to compact its target chromatin. Moreover, the differential effects of Ph and Pc on Hox cluster folding match the differences in ectopic Hox gene expression observed in these two mutants. Our data suggest that PRC1 maintains gene silencing by folding chromatin domains and impose architectural layer to gene regulation.
Cortical modulation of sensory flow during active touch in the rat whisker system
Authors: Chakrabarti Shubhodeep , Schwarz Cornelius 
Published: September 2018

AbstractSensory gating, where responses to stimuli during sensor motion are reduced in amplitude, is a hallmark of active sensing systems. In the rodent whisker system, sensory gating has been described only at the thalamic and cortical stages of sensory processing. However, does sensory gating originate at an even earlier synaptic level? Most importantly, is sensory gating under top-down or bottom-up control? To address these questions, we used an active touch task in behaving rodents while recording from the trigeminal sensory nuclei. First, we show that sensory gating occurs in the brainstem at the first synaptic level. Second, we demonstrate that sensory gating is pathway-specific, present in the lemniscal but not in the extralemniscal stream. Third, using cortical lesions resulting in the complete abolition of sensory gating, we demonstrate its cortical dependence. Fourth, we show accompanying decreases in whisking-related activity, which could be the putative gating signal.