bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengendali Otomasi 3-Axis Berbasis PC pada Simulasi Proses Las
Authors: Hartono Puji , Nauval Fauzi M. 
Published: September 2018

Abstrak Proses pengelasan manual memiliki beberapa kekurangan diantaranya adalah hasil yang kurang homogen dan kuantitas hasil yang terbatas. Pada produksi masal yang membutuhkan kualitas dan kuantitas yang baik, terlebih lagi pada produksi yang harus mengejar kapasitas produksi tertentu tetapi terbatas waktunya, Hal tersebut menjadi latar belakang dilakukannya penelitian ini. Tujuan penelitian ini yaitu untuk meningkatkan kualitas dan kuantitas produksinya tanpa terbatasnya waktu, salah satunya dengan cara melakukan proses otomasi, yakni dengan simulasi pada proses las menggunakan robot 2-axis atau lebih. Dalam penelitian ini, menggunakan metodologi pengendali otomasi 3-axis berbasis PC (Personal Computer) dengan menggunakan robot 3-axis yang dikendalikandengan 3 buah motor stepper, dimana motor stepper tersebut secara hardware dikendalikan oleh driver motor stepper HY-TB3DV-M yang mampu mengendalikan motor sampai 3,5 Ampere. Selain itu, digunakan pula software Mach3 dan EMC2, kedua software tersebut menerima masukan G-Code yang akan diterjemahkan ke dalam robot 3-axis. Hasil penelitian ini bahwa robot 3-axis dapat melakukan gerakan-gerakan seperti yang ada pada proses pengelasan seperti gerakan zig-zag dan gerakan lainnyasesuai dengan G-Code yang dimasukkan ke software seperti yang terlihat dalam simulasi pada proses las. Kode “G-CODE” dapat melakukan semua gerakan berbasis 3-axis. Pengendali otomasi 3-axis menggunakan software berbasis PC ini sebagai alternatif pengganti kontrol unit yang harganya mahal. Kata Kunci : Pengendali otomasi, Otomasi 3-axis, Simulasi proses las, otomasi berbasis PC
KELAYAKAN MODUL PRAKTIK DASAR-DASAR AKUTANSI BERBASIS SPREADSHEET DENGAN PENDEKATAN SIKLUS TRANSAKSI
Authors: Ariana I Made 
Published: September 2018

Tujuan penelitian ini adalah mendeskripsikan dan menguji kelayakan modul praktik dasar-dasar akuntansi berbasis spreadsheet dengan pendekatan siklus transaksi. Metode penelitian yang digunakan adalah penelitian dan pengembangan (Research & Development) model Borg & Gall yang difokuskan pada tahap pengujian kelayakan modul. Subjek uji coba adalah kelompok ahli dan pengguna. Data kualitatif dianalisis dengan teknik analisis kualitatif deskriptif, dan data kuantitatifÂ Â dianalisis dengan menggunakan teknik analisis persentase yaitu dengan membandingkan jumlah jawaban dalam 1(satu) butir dengan jumlah jawaban ideal dalam 1(satu) butir. Kelayakan modul praktik dasar-dasar akuntansi berbasis spreadsheet dengan pendekatan siklus transaksi ditentukan dengan membandingkan persentase aspek yang diukur dengan skala penilaian kelayakan. Simpulan penelitian ini adalah: (1) modulÂ praktik dasar-dasar akuntansi berbasis spreadsheet dengan pendekatan siklus transaksi dikembangkan berdasarkan aplikasi akuntansi berbasis spreadsheet dengan pendekatan siklus transaksi, dan (2) modulÂ praktik dasar-dasar akuntansi berbasis spreadsheet dengan pendekatan siklus transaksi sangat layak dari aspek isi, penyajian, kegrafikaan, dan kebahasaan. Sebagai tindak lanjut hasil penelitian disarankan untuk menggunakan modul praktik dasar-dasar akuntansi berbasis spreadsheet dengan pendekatan siklus transaksi dalam pembelajaran karena berdasarkan hasil penelitian, modul ini dinyatakan sangat layak untuk digunakan dalam pembelajaran. Modul ini juga sangat membantu dosen pengampu mata kuliah dan peserta didik dalam pembelajaran praktik dasar-dasar akuntansi.
MEDIA E-LEARNING BERBASIS CMS JOOMLA: PELENGKAP PEMBELAJARAN FISIKA SMA
Authors: Bakri Fauzi , Fajriani Farah , Muliyati Dewi 
Published: September 2018

Pembelajaran abad 21 harus dilakukan tanpa dipengaruhi batasan ruang dan waktu. Pembelajaran ini harus ditunjang dengan media belajar yang kontekstual, dan multi representasi. Penelitian ini bertujuan untuk menghasilkan perangkat e-learning berbasis Content Management System (CMS)Â Joomla yang layak digunakan dalam pembelajaran fisika di SMA. Metode yang digunakan pada penelitian ini adalah metode penelitian dan pengembangan model Dick and Carey. Perangkat e-learning menampilkan paparan materi secara multi representasi. Materi diperkaya video pembelajaran, latihan soal, perangkat evaluasi pembelajaran, serta forum diskusi untuk memudahkan interaksi antar siswa dan guru. Siswa belajar secara mandiri, tanpa terbatas ruang maupun waktu. Perangkat media e-learning sudah melalui tahap evaluasi formatif dengan menggunakan instrumen skala likert 1-5. Hasil uji kelayakan materi medapat nilai 86,33, kelayakan media 86,3, kelayakan pembelajaran 92,14, uji coba lapangan untuk guru Fisika 91,78, dan uji coba lapangan dengan kuisioner 85,44. Hasil uji coba penggunaan media e-learning sebagai pelengkap pembelajaran memberikan nilai-gain sebesar 0,323. Dari hasil uji kelayakan dan uji lapangan tersebut maka media E-learning berbasis CMS Joomla yang telah dikembangkan dinyatakan layak digunakan dalam pembelajaran fisika SMA dengan kualitas sangat baik. Siswa mendapatkan tambahan pengetahuan cukup signifikan setelah melakukan pembelajaran secara mandiri melalui perangkat e-learning fisika ini. Hal ini mengindikasikan media e-learning fisika SMA yang dikembangkan dengan CMS Joomla dapat digunakan sebagai pelengkap pembelajaran fisika didik SMA.
PENINGKATAN HASIL BELAJAR HIMPUNAN DENGAN MENGGUNAKAN APLIKASI ISPRING SUITE 8
Authors: Martiningsih Raden Roro 
Published: September 2018

Â Penelitian ini dilatarbelakangi oleh kurangnyaÂ pemahaman peserta didik dalam materi himpunan di kelas VII B SMP Muhammadiyah 1 Surabaya. Hal ini disebabkan guru kurang tepat dalam memilih media pembelajaran yang digunakan. Tujuan penelitian ini adalah untuk meningkatkan kemampuan memahami himpunan menggunakan aplikasi iSpring Suite 8. Penelitian ini dilaksanakan dengan dua siklus, di mana setiap siklus diawali dengan perencanaan, tindakan, observasi, dan refleksi. Subyek penelitian adalah peserta didik kelas VII B SMP Muhammadiyah 1 Â Surabaya tahun pelajaran 2017/2018 semester ganjil dengan jumlah peserta didik 38 orang. Data dalam penelitian ini berupa penilaian proses yang diperoleh dari peserta didik dalam beraktivitas dan penilaian pada akhir siklus. Kemudian, data dianalisis untuk memperoleh gambaran tentang berhasil tidaknya pembelajaran yang telah dilakukan. Hasil penelitian menunjukkan bahwa ada peningkatan hasil belajar peserta didik dalam memahami himpunan setelah belajar menggunakan aplikasi iSpring Suite 8 tanpa animasi pada siklus pertama dan aplikasi iSpring Suite 8 dengan variasi animasi, penambahan video, background yang lebih menarik pada siklus kedua. Indikasi peningkatan hasil belajar didasarkan pada perolehan nilai pada siklus pertama dan siklus kedua
A COMPARATIVE STUDY ON THE SAFETY AND EFFECTIVENESS OF GLUCOSAMINE-DIACEREIN AND UNIVESTIN – CHONDROITIN IN KNEE OSTEOARTHRITIC PATIENTS IN A TERTIARY CARE HOSPITAL
Authors: George Dr. Mathew , Joseph Dr. Lincy , Joseph Mrs Jeenu , Biju Becky Maria , Thomas Roshin 
Published: September 2018

Background: Knee Osteoarthritis is a progressive disease showing increasing trend of occurrence in a population .It has lead to great morbidity and disability. Combinations which showed anti-inflammatory property and suppression of cartilage degeneration are better options for management of knee osteoarthritis. According to medical practice, quick relief within short period of exposure to drug therapy is preferred. This study was an attempt to compare the safety and effectiveness of diacerein-glucosamine and univestin-chondroitin combinations in knee osteoarthritic patients in a tertiary care hospital. These drugs are now prescribed by Indian physicians in the current scenario.
Patients and Method: The study began only after getting the approval from Institutional Ethics Committee and obtaining Inform Consent from subjects. The study was conducted in the department of orthopedics in Pushpagiri Medical College hospital, Kerala. From140 patients who arrived at the Orthopedics OPD Pushpagiri medical college hospital, we sorted and selected only 64 patients based on the study criteria. We divided into two groups (32 each) one receiving diacerein-glucosamine and another receiving univestin chondroitin combinations. From these groups grade 1 and 2 patients are subdivided. They were assessed by WOMAC, KOOS, VAS, 6 minute walk test, and Standard ADR questionnaires (Naranjo’s) for measuring safety and effectiveness of drug combinations. Change in the short term effectiveness for both drugs measure was assessed before the start of treatment, and after 30 days of treatment.
Conclusion: For Grade 1 patients both drugs were equally effective. But for Grade 2 Patients diacerein-glucosamine combination therapy shows more benefit than univestin-chondroitin. However, semi-synthetic drug combination showed more safety profile than synthetic drug combination in the short term treatment of knee osteoarthritis.
Keywords : univestin –chondroitin , diacerein-glucosamine , OA , WOMAC , KOOS , VAS
Diuretic activity of aqueous extract and smoothie preparation of Verbesina crocata in rat
Authors: Salazar Anuar Gómez , Pablo Saudy Saret Pérez , Estévez María Mirian Carmona , Meléndez María Estela Camargo 
Published: September 2018

<p>The aim of this study was to evaluate the diuretic activity of aqueous extract of <em>Verbesina crocata</em> at different doses in rat. The aqueous extract (100 and 400 mg/kg for decoction; 200 and 400 mg/kg for smoothie form), furosemide (4 mg/kg and vehicle were administered per os to rat. After 6 hours in metabolic cages, the urinary flow, glomerular ﬁltration rate and electrolyte balance (Na+ and K+) were assessed. All doses produced an increment of urinary flow and Na+/K+ excretion. Glomerular filtration rate was incremented only on smoothie form at 400 mg/kg. These findings provide a basis explaining the traditional folk medicine use of this plant as a diuretic agent.</p><p><strong>Video Clip of Methodology:</strong></p><p>Method for diuretic activity: 1 min 37 sec <a href="https://www.youtube.com/v/8Xk_msiVtLU">Full Screen</a> <a href="https://www.youtube.com/watch?v=8Xk_msiVtLU">Alternate</a> </p>
Nephroprotective effect of Berberis baluchistanica against gentamicin-induced nephrotoxicity in rabbit
Authors: Pervez Samreen , Saeed Muhammad , Khan Haroon , Shahid Muhammad , Ullah Irfan 
Published: September 2018

<p>The present study was conducted to explore the protective effect of <em>B. baluchistanica</em> against gentamicin-induced renal toxicity in rabbits. Phytochemical investigations lead to the isolation of berberine and palmatine. The crude hydro-methanolic extract at various doses (100, 200 and 300 mg/kg body weight) elicited strong nephroprotective effects by restoring various biomarkers which were deranged by gentamicin such as creatinine, urea, serum uric acid levels (p&lt;0.001) in plasma and urine output creatinine clearance, urinary protein and γ-glutamyl transferase level (p&lt;0.001) in urine in a dose dependent manner. The mediators involved in oxidative stress such malondialdehyde, reduced glutathione, glutathione peroxidase, and catalase levels were significantly (P˂0.05-0.001) modulated in kidney tissue homogenate. Correspondingly, there is a significant (P&lt;0.05) recovery in kidney weight and % loss in body weight compare to GM group. From these results, it is possible that<em> B. baluchistanica</em> exhibited protective effect mediated through the presence of berberine and palmatine.</p><p><strong>Video Clip of Methodology:</strong></p><p>Histopathology: 7 min 24 sec <a href="https://www.youtube.com/v/VNa-fDMRosA">Full Screen</a> <a href="https://www.youtube.com/watch?v=VNa-fDMRosA">Alternate</a> </p>
Ameliorating effect of Berberis lycium root bark extracts against cisplatin-induced nephropathy in rat
Authors: Anwar Rukhsana , Sultan Rabeea , Batool Fasiha 
Published: September 2018

<p>The aim of this study was to investigate the sub-acute nephroprotective effect of <em>Berberis lycium</em> root bark extracts against cisplatin-induced nephrotoxicity. Aqueous and methanol extracts (200 and 400 mg/kg) were co-administered with cisplatin (4 mg/kg) for 19 days. Results showed that cisplatin significantly (<sup>a</sup>p&lt;0.05) raised the serum creatinine, uric acid, urea level as well as tissue MDA level as compared to control group. It decreased GST activity, tGSH and catalase activity in rats. Both extracts significantly reduced the serum creatinine, urea and uric acid levels. Moreover, GST, CAT activity and tGSH content were significantly (p&lt;0.05) increased and MDA level was decreased. Histopathological examination showed that both extracts efficiently reversed the morphological changes and damage induced by cisplatin. It is concluded that both extracts of <em>B. lycium</em> root bark possess nephroprotective effect against cisplatin-induced nephrotoxicity.</p><p><strong>Video Clip of Methodology:</strong></p><p>Histological study of rat kidney: 14 min 02 sec <a href="https://www.youtube.com/v/QQGDo8e3HjQ">Full Screen</a> <a href="https://www.youtube.com/watch?v=QQGDo8e3HjQ">Alternate</a></p>
Antibacterial activities of endophytic fungi isolated from six Sri Lankan plants of the family Cyperaceae
Authors: Ratnaweera Pamoda B. , Walgama R. Chandula , Jayasundera Kinkini U. , Herath Suseema D. , Abira S. , Williams David E. , Andersen Raymond J. , De Silva E. Dilip 
Published: September 2018

<p class="Abstract">In a study designed to determine the antibacterial potential of endophytic fungi inhabiting plants of Cyperaceae family, 72 morphologically distinct endophytic fungi were isolated from six plants and their antibacterial activities against two Gram positive and three Gram negative pathogenic bacterial species were examined. Two antibacterial metabolites from two endophytes were also isolated and their chemical structures and minimum inhibitory concentrations were determined. Sixty six fungal extracts (92%) were active against at least one bacterium tested. Butyrolactone I isolated from the Aspergillus terreus and 9-epi viridol isolated from Trichoderma virens exhibited MIC values in the range 128-256 µg/mL against Gram positive Bacillus subtilits, Staphylococcus aureus, methicillin resistant S. aureus (MRSA) and Escherichia coli. Both compounds were inactive against other micro-organisms tested. This study confirmed that Cyperaceae plants harbor numerous endophytes that produce antibacterial metabolites active against both Gram positive and, to a lesser extent, Gram negative bacteria.</p><p><strong>Video Clip of Methodology:</strong></p><p>Column Chromatogrpahy: 15 min 34 sec <a href="https://www.youtube.com/v/CqF3GmhSHN4">Full Screen</a> <a href="https://www.youtube.com/watch?v=CqF3GmhSHN4">Alternate</a></p>
A Galaxy-scale Fountain of Cold Molecular Gas Pumped by a Black Hole
Authors: Tremblay G. R. , Combes F. , Oonk J. B. R. , Russell H. R. , McDonald M. A. , Gaspari M. , Husemann B. , Nulsen P. E. J. , McNamara B. R. , Hamer S. L. , O’Dea C. P. , Baum S. A. , Davis T. A. , Donahue M. , Voit G. M. , Edge A. C. , Blanton E. L. , Bremer M. N. , Bulbul E. , Clarke T. E. , David L. P. , Edwards L. O. V. , Eggerman D. , Fabian A. C. , Forman W. , Jones C. , Kerman N. , Kraft R. P. , Li Y. , Powell M. , Randall S. W. , Salomé P. , Simionescu A. , Su Y. , Sun M. , Urry C. M. , Vantyghem A. N. , Wilkes B. J. , ZuHone J. A. 
Published: September 2018

Abstract
We present Atacama Large Millimeter/submillimeter Array and Multi-Unit Spectroscopic Explorer observations of the brightest cluster galaxy in Abell 2597, a nearby (z = 0.0821) cool core cluster of galaxies. The data map the kinematics of a three billion solar mass filamentary nebula that spans the innermost 30 kpc of the galaxy’s core. Its warm ionized and cold molecular components are both cospatial and comoving, consistent with the hypothesis that the optical nebula traces the warm envelopes of many cold molecular clouds that drift in the velocity field of the hot X-ray atmosphere. The clouds are not in dynamical equilibrium, and instead show evidence for inflow toward the central supermassive black hole, outflow along the jets it launches, and uplift by the buoyant hot bubbles those jets inflate. The entire scenario is therefore consistent with a galaxy-spanning “fountain,” wherein cold gas clouds drain into the black hole accretion reservoir, powering jets and bubbles that uplift a cooling plume of low-entropy multiphase gas, which may stimulate additional cooling and accretion as part of a self-regulating feedback loop. All velocities are below the escape speed from the galaxy, and so these clouds should rain back toward the galaxy center from which they came, keeping the fountain long lived. The data are consistent with major predictions of chaotic cold accretion, precipitation, and stimulated feedback models, and may trace processes fundamental to galaxy evolution at effectively all mass scales.
Discovery of Extended Infrared Emission around the Neutron Star RXJ0806.4–4123*

†
Authors: Posselt B. , Pavlov G. G. , Ertan Ü. , Çalışkan S. , Luhman K. L. , Williams C. C. 
Published: September 2018

Abstract
Following up on a faint detection of a near-infrared (NIR) source at the position of the X-ray thermal isolated neutron star RX J0806.4–4123, we present new Hubble Space Telescope observations in the H-band. The NIR source is unambiguously detected with a Vega magnitude of 23.7 ± 0.2 (flux density of 0.40 ± 0.06 μJy at λ = 1.54 μm). The source position is coincident with the neutron star position, and the implied NIR flux is strongly in excess of what one would expect from an extrapolation of the optical-UV spectrum of RX J0806.4–4123. The NIR source is extended, with a size of at least 0.″8, and shows some asymmetry. The conservative upper limit on the flux contribution of a point source is 50%. Emission from gas and dust in the ambient diffuse interstellar medium can be excluded as a cause for the extended emission. The source parameters are consistent with an interpretation as either the first NIR-only detected pulsar wind nebula or the first resolved disk around an isolated neutron star.
Closure of Large Chronic Macular Hole by Scleral Imbrication and Retinal Expansion
Authors: Chantarasorn Yodpong , Thamsriswadi Patrinee 
Published: September 2018

BACKGROUND AND OBJECTIVE:
The purpose of this study is to describe a new technique for the treatment of large, chronic macular hole (MH) using scleral imbrication and retinal expansion and to report the outcomes of MH closure.

PATIENTS AND METHODS:
This retrospective study demonstrates a procedure for correcting the disproportion between an area of stiff neurosensory retina and the inner scleral wall. Baseline MH parameters were collected. MH closure rate, visual outcomes, and biometry were reported at 6-month follow-up.

RESULTS:

MH closure was achieved in six out of seven patients (85.7%). Mean minimal hole diameter, base hole diameter, and MH index were 712 μm ± 136.8 μm, 1,440 μm ± 444 μm, and 0.27 μm ± 0.08 μm, respectively. At 6-month follow-up, median logarithm of the minimum angle of resolution (logMAR) corrected distance visual acuity significantly improved from 1.2 (interquartile range [IQR] = 1.0 to 1.6) preoperatively to 0.7 (IQR = 0.58 to 0.8) postoperatively (
P
= .018; Wilcoxon signed-rank test).

CONCLUSION:
This technique provided both satisfactory hole closure rates and acceptable structural outcomes.

[
Ophthalmic Surg Lasers Imaging Retina
. 2018;49:e57–e64.]
Fellow Eye Anti-VEGF ‘Crunch’ Effect in Retinopathy of Prematurity
Authors: Wood Edward H. , Rao Prethy , Moysidis Stavros N. , Dedania Vaidehi S. , Elman Michael J. , Drenser Kimberly A. , Capone Antonio , Trese Michael T. 
Published: September 2018

BACKGROUND AND OBJECTIVE:
Anti-vascular endothelial growth factor (VEGF) therapy is increasing in popularity for treatment of retinopathy of prematurity (ROP). Despite many technical benefits, issues remain prompting further investigation.

PATIENTS AND METHODS:
Retrospective case report and literature review.

RESULTS:
A 42-week-old postmenstrual age female with gestational age of 28 weeks and birth weight of 990 g presented with prominent progression of peripapillary purely tractional atypical stage 4A ROP in both eyes following intravitreal bevacizumab therapy in the right eye only.

CONCLUSION:
The authors present the first reported case, to their knowledge, of a “crunch” phenomenon tractional retinal detachment from fellow eye administration of bevacizumab.

[
Ophthalmic Surg Lasers Imaging Retina
. 2018;49:e102–e104.]
Anatomical Changes of Full-Thickness Macular Hole Documented by Microscope-Integrated Spectral-Domain Optical Coherence Tomography
Authors: Gonzalez-Cortes Jesus H. , Estudillo Abel Ramirez , Sanchez-Ramos Jorge A. , Bages-Rousselon Yunuen , Fernandez-Mar Mariana , Mohamed-Hamsho Jesus 
Published: September 2018

BACKGROUND AND OBJECTIVE:
To evaluate anatomical changes of idiopathic macular hole (MH) after internal limiting membrane removal and after passive suction at the hole's borders using microscope-integrated intraoperative optical coherence tomography (iOCT).

PATIENTS AND METHODS:
Five eyes of five subjects with full-thickness idiopathic MH underwent phacoemulsification, intraocular lens implantation, pars plana vitrectomy, and internal limiting membrane (ILM) removal. iOCT was performed after ILM removal and after passive suction at the hole's borders.

RESULTS:
iOCT showed decreased MH diameter after ILM removal in all cases. Passive suction achieved complete apposition of borders. All cases presented successful postsurgical closure.

CONCLUSIONS:
iOCT provides anatomical information during MH surgery that may impact surgical decision-making by allowing a real-time evaluation of structures. iOCT with preservative-free triamcinolone acetonide enhanced ILM visualization. Its use is superior to iOCT alone for the identification of vitreomacular interface structures.

[
Ophthalmic Surg Lasers Imaging Retina
. 2018;49:e105–e111.]
d-Glycero-β-d-Manno-Heptose 1-Phosphate and d-Glycero-β-d-Manno-Heptose 1,7-Biphosphate Are Both Innate Immune Agonists
Authors: Adekoya Itunuoluwa A. , Guo Cynthia X. , Gray-Owen Scott D. , Cox Andrew D. , Sauvageau Janelle 
Published: September 2018

Abstract
d-Glycero-β-d-manno-heptose 1,7-biphosphate (β-HBP) is a novel microbial-associated molecular pattern that triggers inflammation and thus has the potential to act as an immune modulator in many therapeutic contexts. To better understand the structure–activity relationship of this molecule, we chemically synthesized analogs of β-HBP and tested their ability to induce canonical TIFA-dependent inflammation in human embryonic kidney cells (HEK 293T) and colonic epithelial cells (HCT 116). Of the analogs tested, only d-glycero-β-d-manno-heptose 1-phosphate (β-HMP) induced TIFA-dependent NF-κB activation and cytokine production in a manner similar to β-HBP. This finding expands the spectrum of metabolites from the Gram-negative ADP–heptose biosynthesis pathway that can function as innate immune agonists and provides a more readily available agonist of the TIFA-dependent inflammatory pathway that can be easily produced by synthetic methods.