bluuebunny/crossref_metadata_2025_split huggingface dataset:
Applying User-Centered Design Methods to the Development of an mHealth Application for Use in the Hospital Setting by Patients and Care Partners
Authors: Couture Brittany , Lilley Elizabeth , Chang Frank , DeBord Smith Ann , Cleveland Jessica , Ergai Awatef , Katsulis Zachary , Benneyan James , Gershanik Esteban , Bates David , Collins Sarah 
Published: May 2018

Introduction Developing an optimized and user-friendly mHealth application for patients and family members in the hospital environment presents unique challenges given the diverse patient population and patients' various states of well-being.
Objective This article describes user-centered design methods and results for developing the patient and family facing user interface and functionality of MySafeCare, a safety reporting tool for hospitalized patients and their family members.
Methods Individual and group usability sessions were conducted with specific testing scenarios for participants to follow to test the usability and functionality of the tool. Participants included patients, family members, and Patient and Family Advisory Council (PFAC) members. Engagement rounds were also conducted on study units and lessons learned provided additional information to the usability work. Usability results were aligned with Nielsen's Usability Heuristics.
Results Eleven patients and family members and 25 PFAC members participated in usability testing and over 250 patients and family members were engaged during research team rounding. Specific themes resulting from the usability testing sessions influenced the changes made to the user interface design, workflow functionality, and terminology.
Conclusion User-centered design should focus on workflow functionality, terminology, and user interface issues for mHealth applications. These themes illustrated issues aligned with four of Nielsen's Usability Heuristics: match between system and the real world, consistency and standards, flexibility and efficiency of use, and aesthetic and minimalist design. We identified workflow and terminology issues that may be specific to the use of an mHealth application focused on safety and used by hospitalized patients and their families.
Functioning in Women with Cervical Cancer in Brazil: the Perspective of Experts
Authors: Castaneda Luciana , Bergmann Anke , Castro Shamyr , Koifman Rosalina 
Published: May 2018

Objective The objective of this study was to identify the perspective of the specialists about functioning in women with cervical cancer (CC).
Methods A study was conducted with specialists using the Delphi methodology. The specialist contacts were found in oncology organizations and associations, as well as in a referral hospital in the treatment of CC. The questions that the experts answered covered the biopsychosocial domains of the International Classification of Functioning, Disability and Health (ICF).
Results Twenty-five specialists participated in the study. The experts' responses generated 485 significant concepts. The categories that presented the highest frequencies of reporting by the specialists were health services, systems and policies; structure of the reproductive system; health professionals and sexual function.
Conclusion Regarding the perception of the specialists, this study concluded that 24 categories of ICF are the most relevant in the context of functioning in women with CC. The results suggest that the biopsychosocial perspective was incorporated in the experts' perceptions about the functioning phenomenon in women with CC in Brazil.
Evaluation of a Novel System to Enhance Clinicians' Recognition of Preadmission Adverse Drug Reactions
Authors: Smith Joshua , Chen Qingxia , Denny Joshua , Roden Dan , Johnson Kevin , Miller Randolph 
Published: May 2018

Background Often unrecognized by providers, adverse drug reactions (ADRs) diminish patients' quality of life, cause preventable admissions and emergency department visits, and increase health care costs.
Objective This article evaluates whether an automated system, the Adverse Drug Effect Recognizer (ADER), could assist clinicians in detecting and addressing inpatients' ongoing preadmission ADRs.
Methods ADER uses natural language processing to extract patients' medications, findings, and past diagnoses from admission notes. It compares excerpted information to a database of known medication adverse effects and promptly warns clinicians about potential ongoing ADRs and potential confounders via alerts placed in patients' electronic health records (EHRs). A 3-month intervention trial evaluated ADER's impact on antihypertensive medication ordering behaviors. At the time of patient admission, ADER warned providers on the Internal Medicine wards of Vanderbilt University Hospital about potential ongoing preadmission antihypertensive medication ADRs. A retrospective control group, comprised similar physicians from a period prior to the intervention, received no alerts. The evaluation compared ordering behaviors for each group to determine if preadmission medications changed during hospitalization or at discharge. The study also analyzed intervention group participants' survey responses and user comments.
Results ADER identified potential preadmission ADRs for 30% of both groups. Compared with controls, intervention providers more often withheld or discontinued suspected ADR-causing medications during the inpatient stay (p < 0.001). Intervention providers who responded to alert-related surveys held or discontinued suspected ADR-causing medications more often at discharge (p < 0.001).
Conclusion Results indicate that ADER helped physicians recognize ADRs and reduced ordering of suspected ADR-causing medications. In hospitals using EHRs, ADER-like systems could improve clinicians' recognition and elimination of ongoing ADRs.
Periphere Regionalanästhesie ohne Komplikationen – Ein Traum wird wahr?!
Authors: Wiesmann Thomas , Döffert Jens , Steinfeldt Thorsten 
Published: May 2018

ZusammenfassungPeriphere Regionalanästhesieverfahren sind relativ sichere Verfahren der klinischen Anästhesie – dennoch können typische, meist transiente und selten sogar persistierende Komplikationen auftreten. Neben allgemeinen Komplikationen und Strategien zur Risikoreduktion widmet sich dieser Artikel akzidentellen Mitblockaden anderer nervaler Strukturen am Beispiel des Plexus brachialis. Ein Ausblick in die Zukunft informiert über selektivere Blockaden.
Patientenkontrollierte Analgesie: Methoden, Handhabung und Ausbaufähigkeit
Authors: Abrolat Marie , Eberhart Leopold , Kalmus Gerald , Koch Tilo , Nardi-Hiebl Stefan 
Published: May 2018

ZusammenfassungEine nebenwirkungsarme und patientenadaptierte Schmerztherapie ist integraler Bestandteil aller multimodalen Behandlungskonzepte, die eine schnelle und komplikationsfreie Erholung nach operativen Eingriffen ermöglichen sollen. Die patientenkontrollierte Analgesie (PCA) bietet dabei eine etablierte und sichere Option für eine individuell angepasste Schmerztherapie, die – richtig genutzt – ein hohes Maß an Patientenzufriedenheit garantiert.
Organisation der perioperativen Schmerztherapie
Authors: Meißner Winfried , Erlenwein Joachim , Stamer Ulrike 
Published: May 2018

ZusammenfassungOrganisatorische Aspekte der postoperativen Schmerztherapie werden oft vernachlässigt – dabei sind sie ebenso wichtig wie Details zu pharmakologischen oder regionalanalgetischen Verfahren. Anhand virtueller Fragen und Erfahrungen eines Assistenzarztes beleuchten wir in diesem Artikel die „Organisation der perioperativen Schmerztherapie“: Schmerzerfassung und Dokumentation, Patienteninformation und -edukation, Aufgaben eines Akutschmerzdienstes.
Die Bedeutung der Hämolyse in Anästhesie und Intensivmedizin
Authors: Graw Jan , Baron David , Francis Roland 
Published: May 2018

ZusammenfassungDie intravasale Hämolyse mit erhöhten Plasmakonzentrationen von zellfreiem Hämoglobin tritt nicht nur bei hämolytischen Erkrankungen auf – sie ist auch bei der Transfusion von Blutkonserven sowie bei Patienten mit ARDS, Sepsis oder kardiopulmonalem Bypass für den Krankheitsverlauf von Bedeutung. Dieser Beitrag möchte den klinisch tätigen Anästhesisten für die Relevanz der Hämolyse sowie deren Prävention und Früherkennung sensibilisieren.
The impact of language on gesture in descriptions of voluntary motion in Czech and French adults and children
Authors: Fibigerova Katerina , Guidetti Michèle 
Published: May 2018

AbstractThe present study compares adults, five- and ten-year-old speakers of Czech (a satellite-framed language) and French (a verb-framed language) during the task of describing short animated videos displaying various voluntary motion events. In this research domain, Czech is a hitherto unexplored language whose specifics make it interestingly different from other typologically similar languages. Our focus is on the semantic level of the multimodal expression of motion. We found that in spite of substantial differences in their typical verbal patterns due to the particularities of their respective languages, French speakers and Czech speakers tend to produce the same gestural patterns. Although this phenomenon was observed in all age groups, a cross-language positive effect of age on semantic density of speech as well as gesture was also found. These results are discussed in light of models of multimodal development in language acquisition.
YAMDA: thousandfold speedup of EM-based motif discovery using deep learning libraries and GPU
Authors: Quang Daniel , Guan Yuanfang , Parker Stephen C J 
Published: May 2018

Abstract

Motivation
Motif discovery in large biopolymer sequence datasets can be computationally demanding, presenting significant challenges for discovery in omics research. MEME, arguably one of the most popular motif discovery software, takes quadratic time with respect to dataset size, leading to excessively long runtimes for large datasets. Therefore, there is a demand for fast programs that can generate results of the same quality as MEME.

Results
Here we describe YAMDA, a highly scalable motif discovery software package. It is built on Pytorch, a tensor computation deep learning library with strong GPU acceleration that is highly optimized for tensor operations that are also useful for motifs. YAMDA takes linear time to find motifs as accurately as MEME, completing in seconds or minutes, which translates to speedups over a thousandfold.

Availability and implementation
YAMDA is freely available on Github (https://github.com/daquang/YAMDA).

Supplementary information
Supplementary data are available at Bioinformatics online.
Comparison of Clostridioides difficile Stool Toxin Concentrations in Adults With Symptomatic Infection and Asymptomatic Carriage Using an Ultrasensitive Quantitative Immunoassay
Authors: Pollock Nira R , Banz Alice , Chen Xinhua , Williams David , Xu Hua , Cuddemi Christine A , Cui Alice X , Perrotta Matthew , Alhassan Eaman , Riou Brigitte , Lantz Aude , Miller Mark A , Kelly Ciaran P 
Published: May 2018

Abstract

Background
We used an ultrasensitive, quantitative single molecule array (Simoa) immunoassay to test whether concentrations of Clostridioides (formerly Clostridium) difficile toxins A and/or B in the stool of adult inpatients with C. difficile infection (CDI) were higher than in asymptomatic carriers of toxinogenic C. difficile.

Methods
Patients enrolled as CDI-NAAT had clinically significant diarrhea and a positive nucleic acid amplification test (NAAT), per US guidelines, and received CDI treatment. Potential carriers had recently received antibiotics and did not have diarrhea; positive NAAT confirmed carriage. Baseline stool samples were tested by Simoa for toxin A and B.

Results
Stool toxin concentrations in both CDI-NAAT (n = 122) and carrier-NAAT (n = 44) cohorts spanned 5 logs (0 pg/mL to &gt;100000 pg/mL). Seventy-nine of 122 (65%) CDI-NAAT and 34 of 44 (77%) carrier-NAAT had toxin A + B concentration ≥20 pg/mL (clinical cutoff). Median toxin A, toxin B, toxin A + B, and NAAT cycle threshold (Ct) values in CDI-NAAT and carrier-NAAT cohorts were similar (toxin A, 50.6 vs 60.0 pg/mL, P = .958; toxin B, 89.5 vs 42.3 pg/mL, P = .788; toxin A + B, 197.2 vs 137.3 pg/mL, P = .766; Ct, 28.1 vs 28.6, P = .354). However, when CDI/carrier cohorts were limited to those with detectable toxin, respective medians were significantly different (A: 874.0 vs 129.7, P = .021; B: 1317.0 vs 81.7, P = .003, A + B, 4180.7 vs 349.6, P = .004; Ct, 25.8 vs 27.7, P = .015).

Conclusions
Toxin concentration did not differentiate an individual with CDI from one with asymptomatic carriage. Median stool toxin concentrations in groups with CDI vs carriage differed, but only when groups were defined by detectable stool toxin (vs positive NAAT).
Young Somalis’ social identity in Sweden and Britain: The interplay of group dynamics, socio-political environments, and transnational ties in social identification processes
Authors: Scuzzarello Sarah , Carlson Benny 
Published: May 2018

AbstractIn this article, we aim to contribute to the literature on social identification among migrants and minorities by offering a theoretical framework that accounts for the interplay of socio-psychological factors, local and transnational group dynamics, and the socio-political environment in which migrants live. This approach enables us to analyse not only the political significance of identity, but also the psychology of identity formation. Drawing upon qualitative data, we analyse how young Somalis (N = 43) living in the municipalities of Malmö (Sweden) and Ealing (United Kingdom) construct and negotiate their ethnic social identities in relation to: Somali elders living in the same city; Somalis in Somalia and in the diaspora; and the British/Swedish majority society. We show that, to secure a positive self-identity vis-à-vis these referent groups, young Somalis engage in psychological strategies of separation; social competition; and social creativity. The socio-political environment in which they are embedded influences which strategy they adopt.
Untold stories: Jamaican transnational mothers in New York City
Authors: McCallum Derrace Garfield 
Published: May 2018

AbstractGlobalization and contemporary international labour migration continue to transform women’s lives. Moreover, gender stereotypes, biased cultural norms, biological responsibilities and economic marginalization serve to constrain women disproportionately, particularly mothers. Indeed, globalization and migration increases existing pressures associated with motherhood. They intensify societal expectations of women, and often result in extreme distress. Many transnational mothers suffer in silence with little or no chance to share their stories and be heard. This study explores the experiences of Jamaican transnational mothers in New York City and documents their stories in light of current research which investigates how transnational motherhood transgresses gender stereotypes and pushes the boundaries of gender roles and expectations. The stories shared in this paper vividly capture the women’s narratives of loss, longing, empowerment and shared responsibilities across borders.
Paradoxical infrastructures of asylum: Notes on the rise and fall of tent camps in Denmark
Authors: Whyte Zachary , Campbell Rebecca , Overgaard Heidi 
Published: May 2018

AbstractAsylum policies in the Global North have increasingly turned towards populist policies of deterrence, as states attempt to make themselves seem as unattractive as possible to would-be asylum seekers. This article examines one such case: the tent camps for asylum seekers that were hastily erected in Denmark in early 2016. However, while the tent camps surely are an instance of symbolic politics, we argue that to understand their daily operation, attention must also be paid to their infrastructural qualities. Drawing on two months of fieldwork at a tent camp in Næstved, this article examines the ways in which asylum policy and infrastructure interact to shape the daily lives and interactions of camp residents and staff. We propose two paradoxical frames for the analysis, which we term ‘spectacular obscurity’ and ‘successful failure’. The tent camps were trumpeted as symbolic politics, while their daily operation remained obscured, only to burst in to scandal as reports emerged of threatening and violent behaviour on the part of the staff. The tent camps’ infrastructure was constantly failing, as both material and social support broke down, but at the same time these failures successfully formed the basis for the everyday interactions that structured life in the camps. We conclude by questioning the effect of the policies of deterrence as mediated through particular infrastructures, suggesting that the materialities of the tent camps played a more significant role than supposed by policy makers, and that paradoxes of infrastructure provide a useful perspective through which to analyse migration management more broadly.
A classic re-examined: Zelinsky’s hypothesis of the mobility transition
Authors: Skeldon Ronald 
Published: May 2018

AbstractThis paper examines the contribution of Zelinsky’s hypothesis of the mobility transition to research in migration studies over the almost 50 years since its publication in 1971. The transition is placed in the changing contexts of thinking in migration studies of the time and argues that after an initial flurry, followed by a period in the wilderness, it has emerged to guide a new interest in comparative studies on migration. The transition provides a flexible framework that can be modified to give context to the evidence emerging from a number of recent studies that are briefly outlined. Rather than an inflexible linear model, the hypothesis provides scope to incorporate multiple pathways of changing patterns of migration through time and across space. As important, however, has been its role in providing inspiration to guide generations of researchers in migration studies. The transition itself and modern empirical evidence suggest that despite the current concerns about migration, the world is becoming less migratory but more mobile, contradictory though this might at first appear.
Advice Giving in Psychotherapy
Authors: Duan Changming , Knox Sarah , Hill Clara E. 
Published: May 2018

AbstractAdvice giving in psychotherapy has been an area of interest for theorists and practitioners for a long time. However, clear and distinct answers to questions concerning the role of advice in client outcomes have not been as available as one would expect. This state of art may be related to discrepant theoretical positions and the lack of consistent empirical evidence. This chapter argues that some evidence does support advice giving in psychotherapy, depending on the cultural and social context as well as on client and therapist variables. This chapter reviews the literature, recommends a specific model for advice giving, and outlines future research directions.
Advice in Intimate Relationships
Authors: Branch Sara , Hall Elizabeth Dorrance 
Published: May 2018

Abstract
Friendships and romantic relationships are characterized by enduring concern for each other’s welfare. It is perhaps not surprising, then, that advice, a form of social support, is common, expected, and even desired in intimate relationships. While much of the research on advice samples from friendships and romantic relationships, the influence of the specific relational context is often overlooked. This chapter addresses this limitation with a synthesis of theory and research from relationship science. Specifically, it explores the potential contributions of interdependence theory (Kelley & Thibaut, 1978), relationship turbulence theory (Solomon, Knobloch, Theiss, & McLaren, 2016), attachment theory (Bowlby, 1969), and confirmation theory (Dailey, 2006) to understand how relationship cognitions affect advice outcomes. The chapter also discusses the intersections between these theories as applied to advice and shows how these theories can guide best practices of advising in close relationships.
Creative Practices and Technical Processes in Music for Cinema and Television
Authors: Cooper David 
Published: May 2018

Abstract
Film and television composition has always been mediated by technology of one sort or another. From the earliest days of silent film, musicians necessarily had to interact, at the very least, with the mechanically projected image. The subsequent history of the media has been marked by technological advances that mirror broader scientific and engineering innovation, which have impacted the visual and aural domains to equal degrees. This chapter considers the various technical and aesthetic contexts of film and television music composition, the collaboration inherent in its realization, and the limitations that may be placed on the composer’s creative freedom. The chapter concludes with an examination of the archival resources for research in the area, and it uses materials held in the Trevor Jones and Michael Nyman Archives of the University of Leeds throughout to illustrate the discussion.
Sidekick No More Neural Translation Control by p70 ribosomal S6 kinase 1
Authors: Bhattacharya Aditi 
Published: May 2018

Abstract
The p70 ribosomal S6 kinase 1 (S6K1) plays a critical role in stimulus-dependent anabolism in the body and has been the focus of intense study for diseases such as diabetes, cardiac myopathies and cancers, rather than neurological disorders. This chapter evaluates the evidence for S6K1 driven protein synthesis in the brain, its role in mediating learning and memory, dysfunction in disease, and other outstanding questions. S6K1 has been studied for several decades, almost entirely in the context of being the major mediator of translational control downstream of the mechanistic target of rapamycin complex 1 (mTORC1). Interestingly, recent work in neural systems is slowly unravelling the varied roles of S6K1 as a signal aggregator, not limited to mTORC1, to affect neural translation, thus making its involvement in brain function more nuanced than earlier thought.
Owen Lattimore
Authors: Perdue Peter C. 
Published: May 2018

Abstract
The American scholar, traveler, political adviser, and public intellectual Owen Lattimore strongly shaped American public opinion toward China and Central Eurasia in the twentieth century, but he also wrote major works on the geography and environment of the frontiers of Asia that still influence global historians today. His writings asserted the vital importance of China’s relationship with the nomads of the steppe, including the Mongols, for defining the boundaries, cultures, and geopolitical strategy of empires and nation states. He argued for sophisticated explanations of relationships between environmental forces like climate and human culture, and he analyzed China and Central Eurasia so as to provide new perspectives on world history. This article evaluates Lattimore’s contributions to world history in the light of his dynamic political and academic life.