bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case of idiopathic First Bite Syndrome responding to carbamazepine
Authors: Wemyss C. , Gibson J. , Ryan K. 
Published: February 2019

AbstractFirst Bite Syndrome (FBS) is a painful condition which classically presents as severe pain in the pre‐auricular region, initiated on the first bite of a meal. It is usually associated with a history of upper neck surgery or tumour of the parotid salivary gland or parapharyngeal space (PPS). Some propose that FBS arises from damage to, or resection of, the cervical sympathetic trunk resulting in loss of sympathetic innervation to the parotid salivary gland. Idiopathic FBS has been reported only a handful of times in the literature. We present the case of a 51‐year‐old male, urgently referred to the Department of Oral Medicine, with a 3‐week history of severe, sharp, unilateral pain from the right angle of mandible, intensity described as ‘20/10', occurring only on the first bite of eating. This would diminish over 2 min. Clinical examination revealed tenderness over the right condylar neck and angle of mandible only. FBS was suspected and the patient immediately started on carbamazepine. An urgent MRI displayed no abnormalities of the temporomandibular joints, PPS, trigeminal nerve or parotid gland. Restorative Dentistry review confirmed no odontogenic or occlusal cause and on review, 4 months later the patient reported complete resolution of symptoms on 200 mg of carbamazepine three times daily. This case highlights the importance of taking a thorough pain history. Patients with symptoms of FBS and no history of surgery to the neck should have an MRI to rule out parotid gland or PPS tumour. Carbamazepine can be successful in treating idiopathic FBS and can resolve symptoms completely.
Shame, social deprivation, and the quality of the voice‐hearing relationship
Authors: Carden Louise J. , Saini Pooja , Seddon Claire , Evans Emma , Taylor Peter James 
Published: February 2019

ObjectivesMany individuals hold different beliefs about the voices that they hear and have distinct relationships with them, the nature of which may determine the distress experienced. Understanding what factors contribute to these beliefs and relationships and consequently the resulting distress is important. The current research examined whether shame and social deprivation, in a sample of adult voice‐hearers, were related to the relationships that individuals had with their voices or the beliefs that they held about them.DesignThe study utilized a cross‐sectional, Internet‐based design.MethodsEighty‐seven adult voice‐hearers from England were recruited to the online survey. Participants completed measures regarding shame, beliefs about voices, and relationships with voices and provided demographic information and postcodes that were used to refer to Index of Multiple Deprivation data.ResultsSocial deprivation and shame were not associated. Shame was positively associated with variables describing negative voice‐hearing beliefs/relationships but not positive voice‐hearing beliefs/relationships. Principal component analysis on the eight voice‐hearing variables yielded two components related to positive and negative voice‐hearing qualities. A multiple regression conducted on the two components identified that shame was only associated with negative voice‐hearing qualities.ConclusionsThe results suggest that therapies that target shame may be helpful when working with negative voice‐hearing beliefs and relationships. Future research should utilize experimental or longitudinal designs to examine the direction of the relationship.Practitioner pointsThe results contribute to the limited research evidence available regarding the relationship between shame and voice‐hearing.The results suggest the utility of psychological therapies that focus on shame such as compassion‐focused therapy and that conceptualize voices interpersonally such as cognitive analytic therapy.No conclusions can be made regarding causation. The sample size was relatively small, and results cannot be generalized to other areas of the United Kingdom.Future research should utilize experimental and longitudinal designs to examine the impact of shame on voice‐hearing experiences and to examine other factors that may predict shame.
Using paradata to collect better survey data: Evidence from a household survey in Tanzania
Authors: Choumert‐Nkolo Johanna , Cust Henry , Taylor Callum 
Published: February 2019

AbstractData are a key component in the design, implementation, and evaluation of economic and social policies. Monitoring data quality is an essential part of any serious, large‐scale data collection process. The purpose of this article is to show how paradata should be used before, during, and after data collection to monitor and improve data quality. To do this we use timestamps, global positioning system (GPS) coordinates, and other paradata collected from an 800‐household survey conducted in Tanzania in 2016. We demonstrate how key paradata can be used during each phase of a research project to identify and prevent issues in the data and the methods used to collect it. Our results corroborate the importance of collecting and analyzing paradata to monitor fieldwork and ensuring data quality for micro data collection in developing countries. Based on these findings we also make recommendations as to how researchers can make better use of paradata in the future to manage and improve data quality. We argue for an expansion in the understanding and use of varied paradata among researchers, and a greater focus on its use for improving data quality.
Limber pine (Pinus flexilis James) genetic map constructed by exome‐seq provides insight into the evolution of disease resistance and a genomic resource for genomics‐based breeding
Authors: Liu Jun‐Jun , Schoettle Anna W. , Sniezko Richard A. , Yao Fupan , Zamany Arezoo , Williams Holly , Rancourt Benjamin 
Published: February 2019

Summary
Limber pine (Pinus flexilis) is a keystone species of high‐elevation forest ecosystems of western North America, but some parts of the geographic range have high infection and mortality from the non‐native white pine blister rust caused byCronartium ribicola. Genetic maps can provide essential knowledge for understanding genetic disease resistance as well as local adaptation to changing climates. Exome‐seq was performed to construct high‐density genetic maps in two seed families. Composite maps positioned 9612 unigenes across 12 linkage groups (LGs). Syntenic analysis of genome structure revealed that the majority of orthologs were positional orthologous genes (POGs) with localization on homologousLGs among conifer species. Gene ontology (GO) enrichment analysis showed relatively fewer constraints forPOGs with putative roles in adaptation to environments and relatively more conservation forPOGs with roles in basic cell function and maintenance. The mapped genes included 639 nucleotide‐binding site leucine‐rich repeat genes (NBS‐LRRs), 290 receptor‐like protein kinase genes (RLKs), and 1014 genes with potential roles in the defense response and induced systemic resistance to attack by pathogens. Orthologous loci for resistance to rust pathogens were identified and were co‐positioned with multiple members of theR gene family, revealing the evolutionary pressure acting upon them. This high‐density genetic map provides a genomic resource and practical tool for breeding and genetic conservation programs, with applications in genome‐wide association studies (GWASs), the characterization of functional genes underlying complex traits, and the sequencing and assembly of the full‐length genomes of limber pine and relatedPinus species.
The hypersensitive induced reaction 3 (HIR3) gene contributes to plant basal resistance via an EDS1 and salicylic acid‐dependent pathway
Authors: Li Saisai , Zhao Jinping , Zhai Yushan , Yuan Quan , Zhang Hehong , Wu Xinyang , Lu Yuwen , Peng Jiejun , Sun Zongtao , Lin Lin , Zheng Hongying , Chen Jianping , Yan Fei 
Published: February 2019

SummaryThe hypersensitive‐induced reaction (HIR) gene family is associated with the hypersensitive response (HR) that is a part of the plant defense system against bacterial and fungal pathogens. The involvement of HIR genes in response to viral pathogens has not yet been studied. We now report that the HIR3 genes of Nicotiana benthamiana and Oryza sativa (rice) were upregulated following rice stripe virus (RSV) infection. Silencing of HIR3s in N. benthamiana resulted in an increased accumulation of RSV RNAs, whereas overexpression of HIR3s in N. benthamiana or rice reduced the expression of RSV RNAs and decreased symptom severity, while also conferring resistance to Turnip mosaic virus, Potato virus X, and the bacterial pathogens Pseudomonas syringae and Xanthomonas oryzae. Silencing of HIR3 genes in N. benthamiana reduced the content of salicylic acid (SA) and was accompanied by the downregulated expression of genes in the SA pathway. Transient expression of the two HIR3 gene homologs from N. benthamiana or the rice HIR3 gene in N. benthamiana leaves caused cell death and an accumulation of SA, but did not do so in EDS1‐silenced plants or in plants expressing NahG. The results indicate that HIR3 contributes to plant basal resistance via an EDS1‐ and SA‐dependent pathway.
Clinical application of the American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines to small animal cases
Authors: Sharp Claire R. , Goggs Robert , Blais Marie‐Claude , Brainard Benjamin M. , Chan Daniel L. , deLaforcade Armelle M. , Rozanski Elizabeth 
Published: February 2019

AbstractObjectiveTo illustrate the application of the Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines to the management of dogs and cats at risk of developing thrombosis using a case‐based approach.EtiologyDogs and cats become at risk of developing thrombosis from a wide range of conditions. These conditions often involve a specific insult followed by an inflammatory response and when combined with other contributing factors (eg, hypercoagulability, vascular endothelial injury, hemodynamic changes) create favorable conditions for thrombosis.DiagnosisDevelopment of thrombosis in small animals remains challenging to demonstrate. Compatible clinical signs, the presence of known risk factors, and supporting diagnostic tests may be highly suggestive of the development of thrombosis.TherapyTherapeutic recommendations in accordance with the CURATIVE guidelines for dogs and cats are described in specific case vignettes presented. Discussion is centered on antithrombotic drug choices and dosing protocols, as outlined in Domains 2 and 3 of the CURATIVE guidelines. Where appropriate, guidelines related to therapeutic monitoring (Domain 4) and discontinuation of antithrombotics (Domain 5) were included.PrognosisIn small animals at risk of developing thrombosis, overall prognosis may be improved by following consensus‐based recommendations on the use of antithrombotics as outlined in the CURATIVE guidelines. Whether such interventions have any impact on outcome requires further investigation.
Surgical treatment of chronic penile prolapse in Vietnamese pot‐bellied pigs: 5 cases (2016–2017)
Authors: Reig Laia , Hill Jacqueline A. , Mitchell Anna , Hayes Galina , Schlag Ariel N. , Fubini Susan L. 
Published: February 2019

AbstractObjectiveTo describe the surgical treatment and short‐ and long‐term outcome of young pot‐bellied pigs with penile prolapse.Study designShort case series.AnimalsFive young castrated Vietnamese pot‐bellied pigs.MethodsFive Vietnamese pot‐bellied pigs presented with penile prolapse of several weeks duration. No other abnormalities were found at physical examination. Under general anesthesia, phallopexy with or without combined urethropexy was performed successfully in all cases.ResultsAll pigs were discharged from the hospital. One pig required a second urethropexy the day after the initial surgery to improve positioning of the penis in the prepuce. Long‐term outcome was available in 4 cases. Penile prolapse resolved in the 4 cases available for follow‐up, and the owners were satisfied with the cosmetic outcome of the procedure.ConclusionPenile prolapse was successfully corrected in 5 pot‐bellied pigs by using 2 different phallopexy techniques. The procedure was combined with urethropexy in 3 pigs. Long‐term outcome was excellent in the 4 cases available for follow‐up.Clinical impactThis is the first report describing the use of phallopexy with or without urethropexy for successful treatment of penile prolapse in young pot‐bellied pigs. Two different phallopexy techniques were effectively used in this report. The etiology of penile prolapse in pot‐bellied pigs remains unknown.
Feasibility of working with a wholesale supplier to co-design and test acceptability of an intervention to promote smaller portions: an uncontrolled before-and-after study in British Fish & Chip shops
Authors: Goffe Louis , Hillier-Brown Frances , Hildred Natalie , Worsnop Matthew , Adams Jean , Araujo-Soares Vera , Penn Linda , Wrieden Wendy , Summerbell Carolyn D , Lake Amelia A , White Martin , Adamson Ashley J 
Published: February 2019

ObjectivesTo explore the feasibility of working with a wholesale supplier to co-design and deliver, and to assess the acceptability of, an intervention to promote smaller portions in Fish & Chip shops.DesignUncontrolled before-and-after study.SettingFish & Chip shops in northern England, 2016.ParticipantsOwners (n=11), a manager and customers (n=46) of Fish & Chip shops; and intervention deliverers (n=3).InterventionSupplier-led, three-hour engagement event with shop owners and managers, highlighting the problem of excessive portion sizes and potential ways to reduce portion sizes; provision of box packaging to serve smaller portions; promotional posters and business incentives.Data collectionIn-store observations and sales data collected at baseline and postintervention. Exit survey with customers. Semistructured interviews with owners/managers and intervention deliverers postintervention.ResultsTwelve Fish & Chip shops were recruited. Observational data were collected from eight shops: at baseline, six shops did not promote the availability of smaller portion meals; at follow-up, all eight did and five displayed the promotional poster. Seven out of 12 shops provided sales data and all reported increased sales of smaller portion meals postintervention. Of 46 customers surveyed: 28% were unaware of the availability of smaller portion meals; 20% had bought smaller portion meals; and 46% of those who had not bought these meals were interested to try them in the future. Interviews revealed: owners/managers found the intervention acceptable but wanted a clearer definition of a smaller portion meal; the supplier valued the experience of intervention co-production and saw the intervention as being compatible with their responsibility to drive innovation.ConclusionsThe co-design of the intervention with a supplier was feasible. The partnership facilitated the delivery of an intervention that was acceptable to owners and customers. Sales of smaller meal packaging suggest that promotion of such meals is viable and may be sustainable.
Validation of Tokyo Guideline 2013 as Treatment of Acute Cholecystitis by Real World Data
Authors: Harai Shota , Mochizuki Hitoshi , Kojima Yuichiro , Nakagomi Keiko , Yoshimura Dai , Takaoka Shinya , Hosoda Kenji , Suzuki Yoji , Omata Masao 
Published: February 2019

<b><i>Background:</i></b> The Tokyo Guidelines (TG; 2013) indicated that emergency cholecystectomy is an important early treatment option for acute cholecystitis; however, surgical intervention is not necessarily indicated in patients with advanced age. We evaluated percutaneous transhepatic gallbladder aspiration (PTGBA), percutaneous transhepatic gallbladder drainage (PTGBD), and the administration of antibiotics alone as treatment options for acute ­cholecystitis. <b><i>Methods:</i></b> From January 2010 to December 2017, 159 patients with acute cholecystitis were treated at our institution. The data from these patients were retrospectively analyzed. <b><i>Results:</i></b> Of these 159 cases, 109 underwent PTGBA, 28 underwent PTGBD, and 22 were administered antibiotics alone. None of the 159 patients needed urgent (early) cholecystectomy, and all patients were discharged without mortality. PTGBA was unsuccessful in only 6 of 109 patients; PTGBD was performed in these 6 cases. Long-term follow-up was conducted in all cases. Of the 159 patients, 146 had gallbladder stones initially, while 13 had none at the time of presentation. Of these 146 patients with gallbladder stones, 84 underwent elective cholecystectomy, while 62 did not. Of the 84 patients who underwent elective cholecystectomy, 2 developed choledocholithiasis; of the 62 patients who did not undergo elective cholecystectomy, 5 developed choledocholithiasis and 2 developed acute cholecystitis. The incidences of choledocholithiasis and acute cholecystitis did not significantly differ between the 2 groups (<i>p</i> = 0.06). <b><i>Conclusions:</i></b> Despite the recommendations in the TG (2013), emergency cholecystectomy was not needed in any of the present patients with acute cholecystitis. Acute cholecystitis can be successfully treated with ­PTGBA or PTGBD, which are simple procedures with good short- and long-term safety. These procedures are highly recommended for patients with acute cholecystitis, especially in the elderly population.
Clinical Characteristics and Outcomes of Kidney Transplantation under Urgency Priority Condition
Authors: Veras de Sandes-Freitas Tainá , Gomes Ramalho de Oliveira Juliana , Loiola de Alencar Dantas Gilberto , Lobo Mesquita Lucas , Barbosa de Almeida Eliana Régia , de Matos Esmeraldo Ronaldo 
Published: February 2019

<b><i>Background:</i></b> In several countries, patients with end-stage renal disease who are ineligible for dialysis are considered urgency priority (UP) for kidney transplantation (KT) through distinct allocation rules. There are scarce published data on clinical features and outcomes after KT of these patients. <b><i>Methods:</i></b> We retrospectively reviewed and compared demographic and clinical pretransplant characteristics and outcomes after KT of all patients transplanted under UP allocation in a single Brazilian transplant center from January 10 to March 16 (<i>n</i> = 74) and 1: 1 patients transplanted under standard allocation in the same period (<i>n</i> = 74). A propensity score (PS) matching analysis was performed to evaluate risk factors for death-censored graft loss. <b><i>Results:</i></b> UP KT group presented higher percentage of women (58.1 vs. 33.8%, <i>p</i> = 0.005), higher class I (22.2 ± 32.9 vs. 13.1 ± 25.3%, <i>p</i> = 0.027) and class II panel reactive antibodies (11.5 ± 24 vs. 5.2 ± 19.1%, <i>p</i> = 0.002), higher HLA mismatches (4.9 ± 0.9 vs. 3.7 ± 1.2, <i>p</i> &#x3c; 0.001), higher percentage of retransplants (27 vs. 4.1%, <i>p</i> &#x3c; 0.001), and spent longer time on dialysis off the waiting list (WL; 54.5 ± 52.5 vs. 31.2 ± 29.0 months, <i>p</i> = 0.03). After transplantation, UP KT patients presented longer hospital stay (29.3 ± 35.7 vs. 18.5 ± 19.5 days, <i>p</i> = 0.003) and inferior death-censored graft survival at 3 years (82 vs. 95.8%, log rank = 0.016), with 33.3% of graft losses due to vascular thrombosis. In PS-matched multivariable analysis, UP status hazard ratios (HR 4.791, 95% CI 1.052–21.722, <i>p</i> = 0.042) and donor age (HR 1.071, 95% CI 1.003–1.145, <i>p</i> = 0.041) were independent risk factors for death-censored graft loss. <b><i>Conclusion:</i></b> Patients transplanted under UP status remained a longer time on dialysis off the WL, suggesting that long-term dialysis led to exhaustion of accesses. After transplantation, outcomes are inferior and UP status was a risk factor for graft loss. These results point to the need for local policies to encourage and monitor the early referral to KT.
Are Measures of Postural Behavior Using Motion Sensors in Seated Office Workers Reliable?
Authors: Jun Deokhoon , Johnston Venerina , McPhail Steven M. , O’Leary Shaun 
Published: February 2019

Objective: In this study, the reliability of measures of upper body postural behavior (head, thorax, neck, and arm) during sustained office work was evaluated. Background: Although there has been a substantial body of research examining the technical aspects of posture measurement in office workers using motion sensors, there is a paucity of literature examining whether posture-related behaviors are actually consistent among office workers in the field on different days and times. Method: Thirty one office workers performed their usual work for three, 1-hr sessions (two morning sessions and one afternoon session) while wearing wireless motion sensors. Reliability coefficients of the derived measures of postural behavior were calculated. Results: Most (30/31) of the postural behavior measures demonstrated modest to excellent reliability (ICC 2.1: 0.48–0.84). Reliability appeared to be mildly affected by factors such as the time of day recordings were taken and variations in desk setups. Conclusion: The findings suggest these measures may be a reliable method for evaluating postural behavior in the office work environment in future studies. Application: Postural measurement using a technical motion sensor described an acceptable reliability to be used for risk assessment in the workplace. Consideration of assessment time and desk setting would increase the accuracy of postural measurement.
Progressive Jews in Argentina and the Arab-Israeli Conflict: Stances on the Six-Day War (1967)
Authors: Kahan Emmanuel Nicolás 
Published: February 2019

Since the 1947 United Nations resolution on the partition of Palestine and, subsequently, the Israeli Declaration of Independence in 1948, the Israeli-Palestinian issue has played a powerful role in Argentine public space that has not found a concomitant response in academia. The stance with regard to the 1967 Six-Day War taken by an institution that promotes itself as representative of progressive Argentine Jews, the Idisher Cultur Farband (Argentine Federation of Jewish Cultural Institutions—ICUF), undermined certain meanings, ties of solidarity, and modes of representation held by a diversity of actors regarding the existence and legitimacy of the State of Israel. Desde la resolución de 1947 de las Naciones Unidas sobre la partición de Palestina y, posteriormente, la Declaración de Independencia de Israel en 1948, el problema israelí-palestino ha desempeñado un papel importante en el espacio público argentino que no ha encontrado una respuesta concomitante en el mundo académico. La postura con respecto a la Guerra de los Seis Días de 1967 tomada por una institución que se promueve a sí misma como representante de los judíos progresistas argentinos, el Idisher Cultur Farband (Federación Argentina de Instituciones Culturales Judías—ICUF), socavó ciertos significados, vínculos de solidaridad y modos de representación de una diversidad de actores con respecto a la existencia y legitimidad del Estado de Israel.