bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breastfeeding experiences and support for women who are overweight or obese: A mixed‐methods systematic review
Authors: Chang Yan‐Shing , Glaria Amaia Artazcoz , Davie Philippa , Beake Sarah , Bick Debra 
Published: June 2019

AbstractWomen who are overweight or obese have increased health risks during and beyond pregnancy, with consequences for their infants' shorter and longer term health. Exclusive breastfeeding to 6 months has many benefits for women and their infants. However, women who are overweight or obese have lower rates of breastfeeding intention, initiation, and duration compared with women with normal weight. This systematic review aimed to examine evidence of (a) breastfeeding barriers and support experienced and perceived by women who are overweight or obese, (b) support shown to be effective in increasing breastfeeding initiation and duration among these women, and (c) perceptions of health care professionals, peer supporters, partners, and family members regarding providing breastfeeding support to these women. Sixteen quantitative and qualitative papers were included and critically appraised. Thematic synthesis was undertaken to obtain findings. Maternal physical barriers such as larger breasts, difficulties of positioning to breastfeed, delayed onset of lactation, perceived insufficient supply of breast milk, and impact of caesarean birth were evident. Maternal psychological barriers including low confidence in ability to breastfeed, negative body image, embarrassment at breastfeeding in public, and experiencing stigma of obesity were also described. Support from health care professionals and family members influenced breastfeeding outcomes. Education for maternity care professionals is needed to enable them to provide tailored, evidence‐based support to women who are overweight or obese who want to breastfeed. Research on health care professionals, partners, and family members' experiences and views on supporting this group of women to breastfeed is needed to support development of appropriate interventions.
Is the Capgras delusion an endorsement of experience?
Authors: Bongiorno Federico 
Published: June 2019

AbstractThere is evidence indicating that the Capgras delusion is grounded in some kind of anomalous experience. According to the endorsement model, the content of the delusion is already encoded in the Capgras subject's experience, and the delusion is formed simply by endorsing that content as veridical. Elisabeth Pacherie and Sam Wilkinson have in different ways attempted to articulate a comprehensive defence of this strategy, but here I argue that the endorsement model cannot be defended along the lines envisioned by either of them. I then offer a more promising way of spelling out the model, according to which the anomalous experience implicated in Capgras is metaphorical in character.
Mutagenesis of GmFT2a and GmFT5a mediated by CRISPR/Cas9 contributes for expanding the regional adaptability of soybean
Authors: Cai Yupeng , Wang Liwei , Chen Li , Wu Tingting , Liu Luping , Sun Shi , Wu Cunxiang , Yao Weiwei , Jiang Bingjun , Yuan Shan , Han Tianfu , Hou Wensheng 
Published: June 2019

SummaryFlowering time is a key agronomic trait that directly influences the successful adaptation of soybean (Glycine max) to diverse latitudes and farming systems. GmFT2a and GmFT5a have been extensively identified as flowering activators and integrators in soybean. Here, we identified two quantitative trait loci (QTLs) regions harbouring GmFT2a and GmFT5a, respectively, associated with different genetic effects on flowering under different photoperiods. We analysed the flowering time of transgenic plants overexpressing GmFT2a or GmFT5a, ft2a mutants, ft5a mutants and ft2aft5a double mutants under long‐day (LD) and short‐day (SD) conditions. We confirmed that GmFT2a and GmFT5a are not redundant, they collectively regulate flowering time, and the effect of GmFT2a is more prominent than that of GmFT5a under SD conditions whereas GmFT5a has more significant effects than GmFT2a under LD conditions. GmFT5a, not GmFT2a, was essential for soybean to adapt to high latitude regions. The ft2aft5a double mutants showed late flowering by about 31.3 days under SD conditions and produced significantly increased numbers of pods and seeds per plant compared to the wild type. We speculate that these mutants may have enormous yield potential for the tropics. In addition, we examined the sequences of these two loci in 202 soybean accessions and investigated the flowering phenotypes, geographical distributions and maturity groups within major haplotypes. These results will contribute to soybean breeding and regional adaptability.
An unusual cause of graft loss in pediatric liver transplant recipient—Fasciola hepatica
Authors: Kelgeri Chaya , Valamparampil Joseph , Shanmugam Naresh , Srinivas Reddy Mettu , Swaminathan Subramanian , Rela Mohamed 
Published: June 2019

AbstractFascioliasis is caused by the trematode liver fluke Fasciola hepatica. Humans are accidental hosts getting infected after ingesting contaminated plants or water. 90 million people in 75 nations are at risk of infection with F hepatica. Immunosuppressed patients are higher risk of acquiring infection and may present with atypical manifestations. Patients can present with hepatic involvement, biliary features or a combination of both. Confirmation of the diagnosis is by demonstration of live parasites or eggs in bile or feces, serology (immunoelectrophoresis, indirect immunofluorescence, indirect hemagglutination), ELISA, typical imaging findings or a combination of any of the above. The drug of choice for treatment is triclabendazole. Fascioliasis should always be considered as a possibility in post‐LT patients with findings of hepatobiliary disorder from endemic areas. Unfamiliarity with this infection in non‐endemic areas often eludes prompt diagnosis thereby increasing the morbidity. We report the first case of fascioliasis in a pediatric liver transplant recipient leading to graft loss and mortality.
Intellectual functioning and executive functions in children and adolescents with attention deficit hyperactivity disorder (ADHD) and specific learning disorder (SLD)
Authors: Faedda Noemi , Romani Maria , Rossetti Serena , Vigliante Miriam , Pezzuti Lina , Cardona Francesco , Guidetti Vincenzo 
Published: June 2019

Several studies have shown neuropsychological deficits across multiple domains in attention deficit hyperactivity disorder (ADHD) and specific learning disorder (SLD), but differences and similarities between these disorders have been little considered. We were interested in analyzing the intellectual and executive profiles in a sample of children and adolescents, divided according to the diagnosis into the ADHD group and the SLD group, and in identifying the differences and similarities between these disorders. The sample included two clinical groups: the first included 36 children and adolescents with a diagnosis of ADHD (5–15 years; mean = 9.42; SD = 2.22) while the second included 36 children and adolescents with a diagnosis of SLD (7–15 years; mean = 9.43; SD = 2.25). The WISC‐IV was used to measure intellectual ability and the NEPSY‐II was employed to measure executive functions. The results showed that the SLD group had significantly higher scores than the ADHD group on the NEPSY‐II in the inhibition, cognitive flexibility, short‐term verbal memory and verbal working memory domains. The ANCOVA showed differences regarding the FSIQ of WISC‐IV, in that the SLD group obtaining higher scores than ADHD group. Findings showed that ADHD children are more impaired than SLD children, in particular in cognitive inhibition, cognitive flexibility, verbal memory, working memory and intellectual functioning. The recognition of the strengths and weaknesses of children and adolescents with ADHD and SLD allows to outline an educational and clinical intervention focused on their specific executive and intellectual functioning.
Are we underestimating reverse TRALI?
Authors: De Clippel Dorien , Emonds Marie‐Paule , Compernolle Veerle 
Published: June 2019

BACKGROUNDTransfusion‐related acute lung injury (TRALI) is a rare but serious adverse transfusion reaction and is known to be related to anti–human leukocyte antigen (HLA) or anti–human neutrophil antigen (HNA) antibodies in donor plasma. In 2016, four of eight reported TRALI cases could not be explained by donor antibodies. It is assumed that fewer than 10% of TRALI cases are triggered by anti‐HLA or anti‐HNA antibodies in the patient's plasma (reverse TRALI).STUDY DESIGN AND METHODSThree cases of red blood cell (RBC)‐associated and one case of granulocyte‐associated TRALI were investigated. Data were collected on the clinical aspects of the patient and the concerned blood product. Patient's HLA antibodies were determined and the implicated donor was contacted for HLA typing. The HLA antibody identification and strength were assessed using a bead assay (Luminex Single Antigen bead assay, Immucor). For HLA typing, a polymerase chain reaction–sequence‐specific oligonucleotide method was used that also included Luminex detection.RESULTSIn three RBC‐associated TRALI cases, HLA Class I and II antibodies found in the patient's plasma were specific for the HLA type of the transfused leukoreduced blood product. In a fourth case, HLA antibodies were found in a patient who developed TRALI after repeated granulocyte infusions. The HLA antibodies were directed against HLA antigens present on the donor WBCs.CONCLUSIONThe diagnosis of reverse TRALI was retained in four cases, suggesting that reverse TRALI is more frequent than described in the literature, especially in patients with an increased risk for having HLA antibodies.
Evaluation of fecal microRNA stability in healthy cats
Authors: Lyngby Janne G. , Kristensen Annemarie T. , Fredholm Merete , Nielsen Lise N. , Cirera Susanna 
Published: June 2019

AbstractBackgroundGastrointestinal (GI) cancer accounts for 14% of feline malignancies. There is a great need for reliable noninvasive diagnostic biomarkers to reach a timely diagnosis and initiate treatment. Fecal microRNAs (miRNAs) could be such a biomarker and have shown great potential in colorectal screening in people but have yet to be investigated in cats.ObjectivesWe aimed to evaluate the presence and stability of feline fecal miRNA under different storage conditions (room temperature [RT], 4, and −20°C) and to evaluate the expression levels of specific fecal miRNAs collected on three separate days (days 1, 4, and 7) in healthy cats.MethodsHealthy cats were prospectively recruited. Fecal samples were collected, aliquoted, and stored for 24 hours at RT and then transferred to −20°C, stored for 24 hours at 4°C and then transferred to −20°C, or were immediately placed at −20°C on day 1 or at −20°C on days 4 and 7 postcollection. Expression of 22 miRNAs was investigated using quantitative real‐time PCR.ResultsTen miRNA assays worked well, and one, let‐7b, was used for normalization. No differences in miRNA expression were seen between the three storage temperatures for the nine miRNAs investigated. Only miR‐26a showed a significant increase in expression between samples of days 1 and 7. The rest of the miRNAs levels were stable over time.ConclusionsFecal miRNA can be isolated from healthy cats. The expression was stable at different temperatures and for most of the miRNAs over time. Prospective studies evaluating fecal miRNA as biomarkers in cats with GI neoplasia are warranted.
Assessment of hydromorphone and dexmedetomidine for emesis induction in cats
Authors: Nystrom Michael R. , Odunayo Adesola , Okafor Chika C. 
Published: June 2019

AbstractObjectiveTo compare the efficacy of hydromorphone and dexmedetomidine at inducing emesis in cats.DesignProspective, blinded, randomized crossover study.SettingVeterinary university teaching hospital.Animals12 healthy purpose‐bred cats.InterventionsCats were randomly assigned to receive hydromorphone (0.1 mg/kg, subcutaneously) or dexmedetomidine (7 μg/kg, IM). Following administration, the incidences of emesis, number of emetic events, signs of nausea (hypersalivation, lip licking), temperature, heart rate, respiratory rate, and sedation score were recorded for 6 hours.Measurements and Main ResultsEmesis was successful in 9 of 12 (75%) cats when treated with hydromorphone and in 7 of 12 (58%) cats when treated with dexmedetomidine (P = 0.67). Dexmedetomidine was more likely to cause sedation than hydromorphone (P < 0.001). Heart rate in cats was significantly decreased at 1 and 2 hours post‐hydromorphone (P = 0.003, 0.014, respectively) and at 1, 2, 3, 5, 6 hours post‐dexmedetomidine (P = 0.001, 0.003, 0.038, 0.013, 0.001, respectively). Cats were more likely to develop an increase in body temperature with hydromorphone administration although this was not clinically significant.ConclusionsResults of the present study indicate that hydromorphone is an effective alternative to dexmedetomidine for the induction of emesis in cats. Hydromorphone appears to cause less sedation and less decrease in heart rate. Further investigation into the most adequate dose of hydromorphone for optimizing emesis is warranted.
Reviewer Acknowledgements
Authors: Johnson Patricia 
Published: June 2019

Studies in Media and Communication (SMC) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether SMC publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 7, Number 1Adriana Car-Mihec, University of Rijeka, CroatiaAndreas Veglis, Aristotle University of Thessaloniki, GreeceAntonio García Gómez, University of Alcalá de Henares, SpainAslı Sezgin, Osmaniye Korkut Ata University, TurkeyBegoña Montero-Fleta, Universitat Poltècnica de València, SpainCarmen Pérez-Sabater, Universitat Politècnica de València, SpainDiego Santos Vieira de Jesus, International Relations, BrazilJavier Serrano Puche, University of Navarra, SpainJoerg Tropp, Pforzheim University, GermanyNuran E. Isik, Izmir University of Economics, TurkeyWilliam Thomas Howe, University of Oklahoma, USAYoung Joon Lim, University of Texas Rio Grande Valley, USAYuan Gao, Curtin University, Australia Patricia JohnsonEditorial AssistantOn behalf of,The Editorial Board of Studies in Media and CommunicationRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://smc.redfame.com
Stimulation of nicotinic receptors in the suprachiasmatic nucleus results in a higher number of growing follicles and ova shed
Authors: Vieyra Elizabeth , Ramírez Deyra A. , Linares Rosa , Rosas Gabriela , Domínguez Roberto , Morales‐Ledesma Leticia 
Published: June 2019

New Findings
What is the central question of this study?
What is the role of the nicotinic system of the suprachiasmatic nucleus (SCN) in the regulation of follicular growth and ovulation?

What is the main finding and its importance?
The stimulation of the nicotinic system of the pro‐oestrus rat SCN results in an increase in the number of ova shed, in the number of growing ovarian follicles and in the secretion of oestradiol.

AbstractThe timing of the preovulatory luteinizing hormone surge that leads to ovulation depends to a large extent on a functional circadian clock that is localized in the suprachiasmatic nucleus (SCN). The activities of the SCN are regulated by several neurotransmitter systems, including the muscarinic system. Given that acetylcholine binds to muscarinic (mAChRs) and nicotinic (nAChRs) receptors, in the present study, we analysed the effects of unilaterally stimulating nAChRs in the left or right SCN. Stimulation treatment was administered in rats in pro‐oestrus at 09.00 or 19.00 h by injecting 0.3 µl of a nicotine solution (200 µm). The effects of the stimulation were assessed by evaluating the number of ova shed, the number of ovarian follicles, and the levels of oestradiol and progesterone in serum 24 h after treatment. We observed that regardless of the time (4 h after lights on, 09.00 h, or immediately after lights off, 19.00 h) or the side of the SCN treated, the unilateral microinjection of nicotine resulted in a higher number of ova shed and higher number of growing follicles in the ovaries as well as higher oestradiol serum levels. When the nicotine microinjection treatment failed to reach the SCN, the oestradiol levels in serum were similar to those of animals treated with vehicle solution. Based on the current results, we suggest that during pro‐oestrus, the nicotinic neuronal information in the SCN modulates follicular growth and ovulation in a stimulatory manner.
Enhanced needle visibility by microbubbles generated with negative pressure using an in-plane technique
Authors: Liu Yong , Sun Xingxing , Qian Wei , Liu Wantao , Mei Wei 
Published: June 2019

Background and objectivesOur previous work found that needle visibility could be improved by introducing microbubbles into needles. The primary aim of this study was to test the hypothesis that the negative pressure method is superior to two other methods for enhancing needle visibility by introducing microbubbles into needles. The secondary aim was to evaluate the impacts of three factors on the visibility of microbubble-filled needles.MethodsIn the first phase, three methods, including the negative pressure method, the mixing method and commercialized microbubbles, were applied to generate microbubbles inside needles for comparison of visibility in a porcine meat model. In the second phase, three factors were tested with a 2×5×5 factorial design to explore their influence on the visibility of microbubble-filled needles. The three factors included types of needles, insertion angles and types of contents inside needles. Needles filled with saline without microbubbles were used as the control in both phases. Insertion videos were recorded, and ultrasound images of needles were captured for the objective visibility analysis.ResultsNeedle visibility was highest in the negative pressure method group (p<0.001). Needle visibility was mainly determined by insertion angles (p<0.001). Microbubble-filled needles were more visible than control needles at 40°, 50° and 60° (p<0.001, p<0.001 and p<0.001, respectively).ConclusionsNeedle visibility can be significantly improved by microbubbles generated with the negative pressure method when insertion angles are 40°, 50° and 60° in porcine meat.
Characteristics of CO2, water vapor, and energy exchanges at a headwater wetland ecosystem of the Qinghai Lake
Authors: Cao Shengkui , Cao Guangchao , Chen Kelong , Han Guangzhao , Liu Ying , Yang Yufan , Li Xiaodong 
Published: June 2019

Ecosystem carbon dioxide (CO2), water vapor, and heat exchanges in alpine wetlands on the Qinghai–Tibetan Plateau are not comprehensively understood. Thus, we studied variability of net ecosystem CO2 exchange (NEE), ecosystem respiration (Re), gross primary production (GPP), evapotranspiration (ET), and heat fluxes over a headwater wetland ecosystem in the Qinghai Lake region. Results showed that the headwater wetland ecosystem was net CO2 absorption on the annual scale, in which monthly NEE, GPP, and Re in two consecutive years varied from −165.16 to 93 g CO2 m−2 mo−1, 6.66 to 384.45 g CO2 m−2 mo−1, and 6.9 to 232.02 g CO2 m−2 mo−1, respectively. The monthly ET from June to September was smaller than precipitation; these results reversed in the remaining months. Annual ET was 362.1 mm in 2015 and 324.96 mm in 2016. The net radiation (Rn), sensible heat (H), latent heat (LE), and ground heat (G) fluxes showed similar monthly patterns. Values of monthly average half-hour Rn, H, LE, and G at the daytime showed Rn > LE > H > G, and the time of the monthly half-hour G peak obviously lagged the Rn, H, and LE. Monthly average Bowen ratios were <1 from May to October, but it reversed in the rest of the months.
New insights on subsurface energy resources in the Southern North Sea Basin area
Authors: Doornenbal J. C. , Kombrink H. , Bouroullec R. , Dalman R. A. F. , De Bruin G. , Geel C. R. , Houben A. J. P. , Jaarsma B. , Juez-Larré J. , Kortekaas M. , Mijnlieff H. F. , Nelskamp S. , Pharaoh T. C. , Ten Veen J. H. , Ter Borgh M. , Van Ojik K. , Verreussel R. M. C. H. , Verweij J. M. , Vis G.-J. 
Published: June 2019

Abstract
The Southern North Sea Basin area, stretching from the UK to the Netherlands, has a rich hydrocarbon exploration and production history. The past, present and expected future hydrocarbon and geothermal exploration trends in this area are discussed for eight key lithostratigraphic intervals, ranging from the Lower Carboniferous to Cenozoic. In the period between 2007 and 2017, a total of 95 new hydrocarbon fields were discovered, particularly in Upper Carboniferous, Rotliegend and Triassic reservoirs. Nineteen geothermal systems were discovered in the Netherlands onshore, mainly targeting aquifers in the Rotliegend and Upper Jurassic/Lower Cretaceous formations. Although the Southern North Sea Basin area is mature in terms of hydrocarbon exploration, it is shown that with existing and new geological insights, additional energy resources are still being proven in new plays such as the basal Upper Rotliegend (Ruby discovery) for natural gas and a new Chalk play for oil. It is predicted that hydrocarbon exploration in the Southern North Sea Basin area will probably experience a slight growth in the coming decade before slowing down, as the energy transition further matures. Geothermal exploration is expected to continue growing in the Netherlands onshore as well as gain more momentum in the UK.
Stiffness as a control factor for object manipulation
Authors: Kennedy Scott D. , Schwartz Andrew B. 
Published: June 2019

During manipulation, force is exerted with the expectation that an object will move in an intended manner. This prediction is a learned coordination between force and movement. Mechanically, impedance is a way to describe this coordination, and object interaction could be anticipated by setting impedance before the hand moves the object. This strategy would be especially important at the end of a reach, because feedback is ineffective for rapid force changes. Since mechanical impedance is not subject to the time delays of feedback, it can, if set properly, produce the desired motion on impact. We examined this possibility by instructing subjects to move a handle to a specific target position along a track. The handle was locked in place until the subject exerted enough force to cross a threshold; the handle was then released abruptly to move along the track. We hypothesized that this ballistic release task would encourage subjects to modify impedance in anticipation of the upcoming movement and found that one component of impedance, stiffness, varied in a way that matched the behavioral demands of the task. Analysis suggests that this stiffness was set before the handle moved and governed the subsequent motion. We also found separate components of muscle activity that corresponded to stiffness and to changes in force. Our results show that subjects used a robust and efficient strategy to coordinate force and displacement by modulating muscle activity in a way that was behaviorally relevant in the task. NEW & NOTEWORTHY The arm can behave like a spring, and this mechanical behavior can be advantageous in situations requiring rapid changes in force and/or displacement. Selection of a proper “virtual” spring before the occurrence of a rapid transient could facilitate a desired responsive movement. We show that these spring-like arm mechanics, set in anticipation of an instantaneous force change, function as an efficient strategy to control movement when feedback is ineffective.