bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of giant copper deposits driven by rapid uplift and sudden depressurization
Authors: Wang Rui , Luo Chenhao , Sun Yingcai , Wu Shaochen , Xia Xiao-Ping , Wang Xiaolin , Xia Wenjie 
Published: November 2024

Abstract
Porphyry Cu deposits (PCDs) in collisional orogens are new targets for modern mineral exploration. A series of post-collisional (Miocene; 22-12Ma) porphyry copper deposit (PCDs) with Cu reserve over 45 Mt have been discovered in the Gangdese magmatic belt, southern Tibet. These magmas derived from partial melting of sulfide-bearing Tibetan juvenile lower crust are fertile for porphyry Cu in many aspects, such as high oxidation state, and rich volatiles such as water, S, and Cl, but some of individual plutons ended up with economic concentrations. The fundamental question remains what accounts for the significant Cu endowments. We measured the igneous zircon water contents of ore-related and barren high Sr/Y magmas in the Gangdese belt, southern Tibet and found that magmas that produce giant PCDs have lower zircon water contents than barren and small-deposit related magmas. Combined with previous fluid inclusions, magmatic breccias, apatite geochemistry, and thermal histories, which demonstrated higher initial water content in causative porphyries such as giant deposits of Qulong and Jiama, we believe that the lower zircon water content may be attributed to these magmas experiencing of faster cooling and sudden depressurization of a large, primed, volatile-saturated or supersaturated mid-upper crustal magma chamber, which could lead to rapid and voluminous volatile exsolution and fluid discharge. These processes caused intense hydrothermal alteration and large ore deposition. In contrast, magmas that experienced slow cooling and deep emplacement would undergo steady state degassing and weak alteration. The variable intrusive and thermal histories across Gangdese reflects interplay between surface and lithospheric dynamics within the Himalaya—Tibet orogen. Our findings suggest the difference of zircon water content reflects the emplacement rate and depth of granitic body, and therefore may serve as an indicator for tectonics and potential for mineralization.
Porphyry Cu-Mo mineralization at Anabama Hill, Delamerian Orogen, South Australia: Fertility assessment implicated from epidote and chlorite chemistry
Authors: Hong Wei , Fabris Adrian , Gilbert Sarah , Curtis Stacey , Wise Tom , Collins Alan S. 
Published: November 2024

Abstract
Porphyry-style hydrothermal alteration has long been recognized in the Delamerian Orogen, Southeastern Australia. However, the fertility of porphyry prospects in this belt, including the Anabama Hill, remains elusive, due to intermittent exploration activities and sparse exposure. Recent significant discoveries of porphyry-epithermal Cu-Au deposits in the adjacent Stavely Arc have led to renewed exploration interest. Reinvestigation of the Anabama Hill drill cores highlights that K-feldspar-rich and epidote-chlorite-dominated alterations are superimposed by extensive quartz-pyrite ± chalcopyrite ± molybdenite veins with white mica-quartz selvedges, related to early-middle Ordovician granitic stocks. Granodiorite and diorite hosts have diagnostic geochemical characteristics, including high Sr/Y, V/Sc ratios, and listric-shaped REE trends, implying amphibole-leading fractionation due to high water contents in primitive melts. LA-ICP-MS analyses show that characteristic element compositions, e.g., high Fe, Sr, Pb, U and Bi and low Mg and REEs in the Anabama Hill epidote, and high Mn, Zn, Zr and U and low Ca, Ba and Pb in the chlorite, suggest the two minerals resulting from propylitic alteration rather than metamorphism. Compared to well-mineralized porphyry deposits, the epidote shows high Bi, Cu, Sr, Ti, Zr and U, and the chlorite is high in Ti/Sr and Al/Si ratios, implying that they are most likely deposit-proximal or near a heat center. This is supported by intermediate to high temperatures of 200—420°C calculated by chlorite geothermometer. Propylitic epidote and chlorite outside pyrite halos typically define geochemical shoulders by anomalous As-Sb and Mn-Zn highs, 1—1.5 km away from the mineralized centers. Given most of the epidote and chlorite intergrown with sulfides, their close proximity to a likely mineralized center accounts for low to moderate concentrations of distal pathfinder elements and subdued performances on the As-Sb and Mn-Zn fertility plots. Combined with bulk-rock results, proximal-fertility indicators recorded in epidote and chlorite provide encouraging implications for porphyry exploration in the Delamerian belt.
A novel hybrid model for long-term water quality prediction with the ‘decomposition–inputs–prediction’ hierarchical optimization framework
Authors: Han Jianjun , Wang Lingling , Yao Qiwen , Zhu Dawei , Zhu Hai , Xu Jin , Hu Lihan , Yang Xu 
Published: November 2024

ABSTRACT

Accurate, stable, and long-term water quality predictions are essential for water pollution warning and efficient water environment management. In this study, a hierarchical water quality prediction (HWQP) model was developed based on ‘data decomposition–predictor screening–efficient prediction’ via wavelet decomposition, Spearman correlation analysis, and long short-term memory network, respectively. The observed data from 14 stations in the Huaihe River–Hongze Lake system, including ammonia nitrogen (AN) and chemical oxygen demand (COD), were used to make long-term water quality predictions. The results suggested that, compared to existing water quality prediction models, the HWQP model has higher accuracy, with the root mean square errors of 6 and 17% for simulating AN and COD, respectively. The AN and COD concentrations will range from 0 to 1 mg/l and from 3 to 5 mg/l at 12 stations, respectively, and the COD concentrations will exceed the water quality target at Stations 4 and 5. The established model has great potential to address the challenges associated with the water environment.
Aortic root reimplantation in patients with bicuspid and tricuspid aortic valve: a systematic review
Authors: Kokorin A.V. , Aminov V.V. , Lukin O.P. , Bogachev-Prokophiev A.V. 
Published: November 2024

Introduction: Valve-preserving operations are gaining popularity in the surgical treatment of aortic root aneurysms in patients with both tricuspid aortic valve (TAV) and bicuspid aortic valve (BAV). Most studies are focused on the results of valvepreserving procedures in patients with TAVs.
Objective: The study takes a comparative assessment of clinical results on aortic root reimplantation in patients with TAV and BAV.
Methods: The systematic review was accomplished according to the PRISMA 2020 criteria. Search for published papers involving comparison of the results on the valvepreserving aortic root reimplantation in patients with TAV and BAV was conducted in three main electronic databases, namely Medline [PubMed], Web of Science, and Google Scholar. The review only included studies, which involved patients of both groups, differed by the anatomy of the valve; studies based on one examination group were excluded.
Results: We revealed that 13 articles met the inclusion criteria. In total, the review involved the treatment results of 3,191 patients, of whom 608 had a BAV and 2,583 had a TAV; patients of comparison groups were similar by sex and age. In most studies, hospital mortality did not exceed 1%. Patients with BAV and TAV showed no significant differences in freedom from aortic regurgitation (AR) ≥ II and long-term survival in 5, 10, 15, and 20 years. However, certain studies noted that patients of the BAV group had a significantly higher reoperation rate than those with TAV (p = 0.026 and p = 0.002).
Conclusion: Reimplantation provides excellent survival for long-term follow-up periods with a low risk of reoperation and recurrence of aortic regurgitation in patients both with TAV and BAV.
Received 4 July 2024. Revised 15 September 2024. Accepted 19 September 2024.
FundingThe research was carried out within the framework of the grant of the Russian Science Foundation No. 23-15-00434.
Conflict of interestThe authors declare no conflict of interest.
Contribution of the authorsThe authors contributed equally to this article.
Design, Synthesis, and Antitumor Potential of New Thiazole--contained 5-Fluoro-2-Oxindole Derivatives as Sunitinib Analogues
Authors: Semenyuta Ivan , Los Oleksandr , Sinenko Vitalii , Zhirnov Victor , Potikha Lyudmyla , Kobzar Oleksandr , Brovarets Volodymyr 
Published: November 2024

Background:
Indole is considered the most promising scaffold for anticancer
drug design due to its high bioavailability, unique chemical properties, and broad spectrum
of pharmacological action.

Objective:
Twelve novel thiazole-containing the 5-fluoro-1,3-dihydro-2H-indol-2-one
derivatives as sunitinib analogs were designed and synthesized, and their anticancer activity
was evaluated against the NCI-60 cancer cell lines.

Method:
The thiazole-contained 5-fluoro-1,3-dihydro-2H-indol-2-one derivatives were
synthesized using Knoevenagel condensation of 1,3-thiazole-5-carboxylic acid 1. Their
anticancer activities were evaluated by NCI-60 one-dose screen assay. The molecular
docking studies were performed using AutoDock tools and the AutoDock Vina programs.
The ADMETlab 2.0 web server predicted the physicochemical properties of compounds.

Results:
Among the synthesized new 5-fluoro-2-oxindole derivatives, compound 3g demonstrated
high antitumor activity (GI>70%) against eight types of cancer: leukemia,
breast cancer, ovarian cancer, lung cancer, melanoma, CNS cancer, renal cancer, and
colon cancer. The most activity was observed against breast cancer (T-47D,
GI=96.17%), lung cancer (HOP-92, GI=95.95%), ovarian cancer (NCI/ADR-RES,
GI=95.13%), and CNS cancer (SNB-75, GI=89.91%). The molecular docking results of
compound 3g demonstrated the possibility of inhibiting VEGF2 receptors as his potential
anticancer mechanism. The physicochemical properties predicted for compounds 3f
and 3g showed positive results.

Conclusion:
Compound 3g demonstrated high in vitro NCI-60 anticancer activity
against nine cancer types and showed cell growth inhibition against leukemia, CNS, and
breast cancer at 6 - 31% higher than Sunitinib, and may represent the basis for further
modification of the thiazole-containing analogs of the anticancer drug Sunitinib.
Topical Herbal Products as Adjuncts to Standard Care for the Management of Diabetic Foot Ulcers
Authors: Mahmood Barakat Abdelreheem , Youssef Hoda A.A. , Mohamed Basma Ahmed , Radwan Amr , Elghouneimy Mohamed A. , Mohamed Nermen Abdelftah , El El Saghier Entesar Omer Ahmed , Abd Elkader Tamer Mohamed , El sheref Saad El Deen , Abd El Fattah Mahmoud Osama Ahmed , Shawky Taiseer Ahmed , El- senosy Fatma M. , Nassar Youssef Abdallah , Khalil Farag , Zidan Hendawy , Elbwab Ahmed Farag Abd Elkader , Abdalla Amany M. 
Published: November 2024

Background and Aim:
Diabetic foot ulcers (DFUs) constitute one of the most debilitating
complications of diabetes mellitus (DM). The use of topical herbal products as adjuvant agents in
wound dressing is one of the most widely used practices worldwide. The present review aimed to
provide a detailed and comprehensive systematic review focusing on randomized clinical studies and
critically analyze not only the clinical outcomes but also the methodological approaches used by
these studies.

Methods:
The present systematic review was conducted according to the Preferred Reporting Items
for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. For the extraction of relevant
studies, three databases were searched: Pubmed, Web of Science Core Collection, and Scopus
by two independent researchers.

Results:
A search of the three databases resulted in the identification of 5528 records which were
reduced to 3224 after removal of duplicates. The application of inclusion and exclusion criteria left
35 full-text articles assessed for eligibility. Finally, 13 articles were excluded and only 22 articles
were advanced to the final analysis. Most studies reported details of local ulcer management only
while others reported the additional systemic/surgical measures used for management. The present
review identified 18 botanical agents/preparations used alone or in combination with other agents as
adjuvant agents in treatment of DFUs. In most situations, these agents proved to be effective.

Conclusion:
The present review reported the methodological approaches and clinical outcomes of
botanical extracts used topically for the treatment of diabetic foot ulcers in randomized controlled
studies. These agents proved to be generally effective. However, many gaps existed in the study
designs which may limit the evidence-based value of these studies.
Sobre el rol de la simpatía en la expresión estética: Theódore Jouffroy y Sully Prudhomme
Authors: Hernández Moredo Linet 
Published: November 2024

El lugar de la simpatía en la reflexión estética decimonónica es probablemente más prominente y extenso de lo que tradicionalmente han reconocido las historias de la estética. Un interés en recuperar arsenal teórico sobre el tema, que nos estimule a entender mejor las ricas implicaciones de ese fenómeno subjetivo e intersubjetivo para el arte y la comunicación estética en general, en un mundo altamente estetizado, mueve a este artículo. Se busca contribuir a divulgar y reconocer los aportes de dos pensadores de la tradición francesa poco recordados en el ámbito de la estética: Théodore Jouffroy (1796-1842), quien marca una pauta en el ámbito de la reflexión estética sobre la simpatía, y Sully Prudhomme (1839-1907), que propone una teoría de la expresión en las artes fundamentada en la simpatía. Se expone la comprensión de Théodore Jouffroy de lo estético como el ámbito de lo expresivo-simbólico, así como su visión del hecho estético, que integra simpatía y expresión en una relación entre sujeto y objeto. Asimismo, se trata la relación de la simpatía con el placer estético en la visión de este pensador. Seguidamente, se analiza la teoría de Sully Prudhomme sobre la expresión artística. Se argumenta la influencia de Jouffroy en su obra; además, se determinan algunos puntos de contacto y otros en los que Prudhomme se distingue.
Experiencia y satisfacción del paciente con los cuidados de enfermería en el servicio de emergencias
Authors: Sánchez Quispe Diego , Ortiz Romaní Katherine Jenny , Portocarrero Reátegui Teresa , Ortiz Montalvo Yonathan Josué 
Published: November 2024

Introducción: La satisfacción del paciente con el cuidado de enfermería es un predictor importante para evaluar la calidad de la atención hospitalaria. Sin embargo, en Perú, la satisfacción y la experiencia del paciente sobre el cuidado de enfermería en el servicio de Emergencias sigue siendo desconocida. Objetivo: Analizar la experiencia y la satisfacción con los cuidados de enfermería percibidas por pacientes hospitalizados en el servicio de emergencia en un hospital de nivel III de Perú. Metodología: Se aplicó el Cuestionario de Calidad del Cuidado de Enfermería que se clasifica en dos dimensiones: experiencia y satisfacción. Las variables independientes fueron factores sociodemográficos y clínicos. Se utilizó la prueba de Chi-cuadrado y la regresión de Poisson para calcular la razón de prevalencia (RP) con un p-valor menor a 0.05. Resultados: De 130 pacientes relevados, el 52,08 % percibió una mala experiencia y el 54,62 % estuvo insatisfecho con los cuidados de enfermería. La edad se asoció con las dimensiones experiencia (RPa: 1.01) y la satisfacción de cuidados de enfermería (RPa: 1.02). Además, el nivel socioeconómico medio-alto (RPa: 0.52) y los días de estancia hospitalaria (RPa: 0.65) se asociaron a una mala satisfacción. Conclusiones: Más de la mitad de los pacientes manifestaron una mala experiencia e insatisfacción con los cuidados recibidos. Esto implica la necesidad de tomar en cuenta las necesidades del paciente hospitalizado en emergencias y gestionar recursos humanos y materiales.
Explorando las técnicas de doma tradicional en caballos cuarto de milla en la capital del Ariari
Authors: Villamizar Castro Hernando Arturo , Gutierrez Castro Litsy Luciene 
Published: November 2024

Contextualización: La interacción entre humanos y caballos ha sido fundamental a lo largo de la historia, siendo la doma tradicional un aspecto crucial en el manejo equino; este estudio, se enfoca en comprender las respuestas de los caballos Cuarto de Milla a las diferentes técnicas o métodos de la doma tradicional empleada en el municipio de Granada Meta.
Vacío de Conocimiento: A pesar de la relevancia histórica de la doma, existe un vacío en la comprensión detallada de cómo los diferentes métodos empleados durante la doma afectan el bienestar de los caballos, por lo que este estudio contribuye al campo, al explorar estas respuestas y sus implicaciones en el bienestar equino.
Propósito: El objetivo principal es caracterizar las respuestas de los caballos Cuarto de Milla a distintos métodos usados dentro de la doma tradicional, buscando identificar el impacto de estas prácticas en el comportamiento y bienestar de los equinos.
Metodología: Se empleó una metodología de investigación cualitativa, utilizando una Checklist diseñada específicamente para este estudio, se obtuvo información complementaria desde referentes antrópicos experimentados y en tiempo real se observaron las respuestas de los caballos a lineamientos como la monta inicial en bruto, uso de riendas sin embocaduras y entrenamiento en libertad.
Resultados y Conclusiones: Los resultados revelaron variaciones significativas en las respuestas de los caballos a los diferentes métodos usados durante la doma y se observó que el trato suave y respetuoso, el uso de riendas sin embocaduras y las ayudas del talón sin espuelas generó una adaptación más rápida y una menor manifestación de estrés en comparación con otros métodos. Estos hallazgos destacan la importancia de considerar el bienestar animal al emplear diferentes métodos de doma tradicional y resaltan la necesidad de técnicas más suaves y progresivas para mejorar la adaptación de los caballos Cuarto de Milla.
The use of financial mathematics from a freirean view in teaching exponenntial function
Authors:   University States of Rio Grande do Sul, Brazil, Marta Aparecida Serpa 
Published: November 2024

This research proposes the development of educational materials as an educational product for teaching exponential functions in the 1st year of high school, focusing on financial mathematics from a Freirian perspective. It aims to bring real-world problems into the classroom, providing students with an authentic environment for applying their knowledge, enabling them to understand and apply what has been developed in class in everyday situations. The proposal offers an alternative to the traditional teaching of this content, aiming for a learning environment that builds connections with the world in which the student is situated. The materials created will be available in an institutional repository under a Creative Commons license and will be evaluated through qualitative and quantitative questionnaires answered by research participants, as well as through the researcher’s observations. The choice to work with financial education, incorporating situations that are part of the students’ real-world experiences, in teaching this specific content, aims to overcome the difficulties that students often encounter in understanding it through traditional methods, providing alternatives for teachers in teaching this content.
Bezděk’s melodrama Danced like the devil and possibilities of its interpretation
Authors:   National Museum – Czech Museum of Music, Věra Šustíková ,   Academy of Performing Arts in Prague
Published: November 2024

The contribution deals with the issue of interpretation possibilities of one specific work, and in the case of melodrama it is a two-stage interpretation. The composer already performs the first interpretation of the text with his music. Interpreters must therefore respect his concept of the text set to music, which can be objectively ascertained by comparing the analysis of the text and its setting to music. Despite the learned respect for the intention of the composer, individual interpretive creations can in the end differ considerably, especially in the interpretation of the textual component, into which the reciter also brings his specific attitude, experience, etc.
Dakwah Media Radio Jakarta Islami Center (JIC) di Era Digital
Authors: Choiri Moh. Amir , Yosepin Pipin 
Published: November 2024

The development and advancement of today's technological world have helped overcome various obstacles in life. In the digital era, the fulfilment of information needs is a necessity that cannot be denied. Da'wah through radio media radio owned by the DKI Jakarta government is one of the radios that broadcast Islamic da'wah. Radio as a broadcasting media also has a role in its da'wah mission. Like Radio Jakarta Islamic Center by implementing da'wah programs in its broadcast content. It's broadcast content. This writing aims to describe the role of da'wah through JIC radio media in the digital era. Researchers conducted in-depth interviews with interviewing informants including the head of the JIC radio da'wah program, the head of JIC radio, and two JIC radio broadcasters.JIC, and two JIC radio broadcasters. The data analysis technique is carried out by the results showed that the role of JIC radio media da'wah in the digital era is increasingly enhanced following the development of the JIC radio program. The digital era is increasingly being improved by following technological developments and the use of social media such as YouTube and others. Radio JIC uses some creative strategies when there is media convergence to improve the quality of broadcasters and can to improve the quality of broadcasters and can strive for broadcasters to present material well.
Keywords: Digital Era, Da'wah, Media Convergence, Radio JIC
Compressive behavior of fiber-reinforced concrete strengthened with CFRP strips after exposure to temperature environments
Authors: Abadel Aref A. , Alharbi Yousef R. 
Published: November 2024

Abstract
Reinforced concrete constructions are extremely vulnerable to fire damage over their lifespan. Despite its non-flammability, concrete is nonetheless affected by fire exposure, which impacts its stress–strain characteristics and durability. Therefore, developing strengthening methods is an economical option compared to the costs of demolishing and rebuilding constructions. This article aims to experimentally and numerically examine the strengthening of fiber-reinforced concrete cylinders by using carbon fiber-reinforced polymer (CFRP) strips after exposure to 600°C. Four different concrete mixtures have been investigated. A total of 48 cylinders were subjected to axial compression testing. The testing program primarily focused on three variables: (i) exposure temperature (600°C); (ii) the effect of using various types of fibers (steel fiber, polypropylene, and hybrid fibers); and (iii) CFRP strengthening. Finite element (FE) models were created using the ABAQUS program to conduct numerical analysis of concrete cylinders in exposure to heating scenarios and strengthen them with CFRP strips. The results show that when subjected to a temperature of 600°C, the compressive strength decreased significantly, ranging from 23.7 to 53.3%. The presence of fibers significantly impacted compressive strength, regardless of the fiber type, leading to an enhanced ratio of up to 34.7% in comparison to the control cylinders (i.e., unheated and unstrengthened cylinders). The suggested strengthening procedures using CFRP strips effectively repaired the heat-damaged cylinders, surpassing the initial compressive strength of unheated cylinders. The FE prediction shows satisfactory, consistent results in comparison to experimental data.