bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application interactive methods and technologies of teaching chemistry
Authors: Sadykov Timur , Čtrnáctová Hana 
Published: September 2019

Abstract
Currently, chemistry education solves problems related to the definition of new values in order to improve the quality of education, personal development of the pupils, and problems of the teaching strategies that will stimulate the interest and commitment of the students for the natural sciences. The emphasis is on interactive teaching, using the subject matter in practice with ICT. Therefore, our goal is to create and verify an interactive chemistry course for lower secondary schools based on the characteristics of interactive, ICT-connected education and more interesting presentation of the subject matter. The first stage of our work consisted of an analysis of previous studies to establish the theoretical foundations on which to the base the use of ICT. Next, we have presented some of the developed methodological options, which illustrate the ability to use interactive methods. In the second stage, according to the different interactive chemistry programs and analysis of curriculum of the chemistry subject in the Czech Republic and Kazakhstan, we developed interactive teaching materials for chemistry lessons with interesting embedded content for lower secondary schools. In the next stage, all prepared materials will be verified and eventually adapted into the final form for use in chemistry teaching.
Association between tumor necrosis factor-α gene-1031T/C promoter polymorphism and endometriosis in a European population
Authors: Drakou Anastasia , Mavrogianni Despoina , Ntzeros Konstantinos , Protopapas Athanasios , Drakakis Petros , Loutradis Dimitrios 
Published: September 2019

AbstractBackgroundTumor necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine which plays an important role in the pathogenesis of many diseases. Endometriosis is one of the most common gynecological diseases. The purpose of this study was to investigate the association of TNF-α-1031T/C polymorphism with the genetic susceptibility of endometriosis in a European population.Materials and methodsIn this case-control study, 51 endometriosis patients and 67 healthy control women participated. We used endometrial tissue from the patients and peripheral blood from the healthy women to extract DNA. Polymerase chain reaction (PCR) analysis and the restriction enzyme Bbs I were used to analyze the -1031 T/C polymorphism in theTNF-αgene promoter region. Statistical analysis was performed using Fisher’s exact test. We also calculated the odds ratios.ResultsIn the group of patients, 66.7% of women were detected with the TT genotype, 33.3% with the TC genotype and 0% with the CC genotype while in the control group, 46.3% had the TT genotype, 47.8% had the TC genotype and 6% had the CC genotype. There was a significant association between the TT genotype with endometriosis (p = 0.03). There was no significant deviation from the Hardy-Weinberg equilibrium.ConclusionsThe TC and CC genotypes appeared more often in the healthy women than the endometriosis patients and this shows that the C allele might have a protective role in endometriosis in the Greek population. Further studies are needed to specify the role of this polymorphism in pathogenesis of endometriosis and the mechanisms that protect the patients from the disease.
Effects of Microwave and Cold Plasma Assisted Hydrodistillation on Lemon Peel Oil Extraction
Authors: Pragna C. H. , Ranjitha Gracy T. K. , Mahendran R. , Anandharamakrishnan C. 
Published: September 2019

Abstract
This study aimed to investigate the effect of low-pressure dielectric barrier discharge (DBD) plasma on microwave-assisted hydrodistillation of lemon peel oil extraction. Microwave pre-treated lemon peel powder was exposed to plasma treatment (1.0, 1.5, 2.0, and 2.5 kV) for 10 min. The treated lemon peel powders were subjected to hydrodistillation to extract the essential oil and the extraction yields were calculated. The extracted oil was analyzed for chemical composition with gas chromatography-mass spectrometry (GC-MS). Effect of plasma on the surface morphology of the lemon peel was observed in a scanning electron microscope (SEM) which revealed the formation of fissures and cracks owing to the higher extraction yield. Plasma treatment at 2.5 kV was observed higher extraction yield than conventional hydrodistillation (149.34 % rise) and the chemical composition of plasma treated sample essential oil remains significantly unchanged. Thus, DBD plasma could be a promising technique to enhance the lemon peel essential oil extraction.
Holistic Nursing Values in Nurse Practitioner Education
Authors: Kinchen Elizabeth 
Published: September 2019

AbstractMuch has been written about the inclusion of holistic nursing values and practices in undergraduate nursing education, but their inclusion and influence in advanced practice nursing education has not been fully explored. Nurse practitioners (NPs) are nurses, so it is assumed that the nursing perspective provides a framework for NP education and practice, and that NP education represents the blending of a holistic nursing approach with medical diagnosis and treatment. Nurse practitioners are taking increasing responsibility for filling the gap in primary healthcare availability in the U.S., and in the current political and economic healthcare climate, NPs are in a position to promote primary care models that honor comprehensive, patient-centered, and relationship-based care. As a result, it becomes essential to quantify the inclusion of these values in NP educational programs and coursework, as instilling core values for practice begins in educational environments. This quantitative, descriptive study explored the inclusion of holistic nursing values by NP faculty, using the Nurse Practitioner Holistic Caring Instrument (NPHCI). The NPHCI exhibited quite high reliability and validity in the sample, including confirmation of its three subscales. Survey results suggest that NP faculty actively incorporate holistic nursing values in educational coursework, and that age, length of time teaching in NP programs, highest educational degree, and academics as the primary area of practice were important indicators of the inclusion of holistic nursing values in NP program curricula. Findings add to knowledge of NP education, but further study is warranted.
Nursing Students’ Perceived Self-Efficacy and the Generation of Medication Errors with the Use of an Electronic Medication Administration Record (eMAR) in Clinical Simulation
Authors: Chan Ryan , Booth Richard , Strudwick Gillian , Sinclair Barbara 
Published: September 2019

AbstractMedication errors continue to be a significant issue, posing substantial threats to the safety and well-being of patients. Through Bandura’s theory of self-efficacy, nursing students’ self-efficacy (confidence) related to medication administration was examined to investigate its influence on the generation of medication errors with the use of an Electronic Medication Administration Record (eMAR) in clinical simulation. This study examined the generation of medication errors and the differences that may exist based on nursing students’ perceived confidence. The findings of this study demonstrated that nursing students continue to generate medication errors within clinical simulation. No differences in the generation of medication errors were found between nursing students with perceived high levels of confidence and those with perceived low levels of confidence (one exception noted). Further examination of the variables and contextual factors related to safe medication administration practices is required to inform nursing education and practice.
A note on the effect of surface topography on adhesion of hard elastic rough bodies with low surface energy
Authors: Violano Guido , Demelio Giuseppe , Afferrante Luciano 
Published: September 2019

AbstractAdhesion between bodies is strongly influenced by surface roughness. In this note, we try to clarify how the statistical properties of the contacting surfaces affect the adhesion under the assumption of long-range adhesive interactions.Specifically, we show that the adhesive interactions are influenced only by the roughness amplitude hrms, while the rms surface gradient h0rmsonly affects the non-adhesive contact force. This is a remarkable result if one takes into account the intrinsic difficulty in defining $h_{\mathrm{rms}}^{^{\prime }}.$Results are also corroborated by a comparison with self-consistent numerical calculations.
microRNA-16 via Twist1 inhibits EMT induced by PM2.5 exposure in human hepatocellular carcinoma
Authors: Zhang Hao , Li Zhihu 
Published: September 2019

Abstract
Epidemiological study has confirmed that PM2.5 (particulate matter with an aerodynamic diameter less than 2.5 μm) is associated with the incidence and progression of human hepatocellular carcinoma (HCC). Accordingly, this study was undertaken to investigate the pro-metastatic effects of PM2.5 on human HCC cell line SMMC-7721 in vitro and to explore the underlying mechanisms. CCK-8 assay was performed to examine the effect of PM2.5 on the proliferation of SMMC-7721 cells; scratch wound assay and transwell matrigel system has been used to examine the effect of PM2.5 on the migration and invasion ability of SMMC-7721 cells; furthermore, effect of PM2.5 on epithelial mesenchymal transition (EMT) of SMMC-7721 cells were examined by examining the EMT markers vimentin, ɑ-smooth muscle actin (ɑ-SMA), and E-cadherin; furthermore, the roles of microRNA-16 (miR-16) and its target Twist1 in PM2.5 induced carcinogenic effects were also examined. Results of CCK-8 assay suggested that PM2.5 promoted the proliferation of SMMC-7721 cells in a dose and time dependent manner. PM2.5 also markedly promoted the migration and invasion ability of SMMC-7721 cells. Moreover, epithelial mesenchymal transition (EMT) was also triggered by PM2.5. On the other hand, microRNA-16 (miR-16) and its target Twist1 was found to be mediated by PM2.5, and miR-16 mimic could suppress the metastatic ability of SMMC-7721 cells exposure to PM2.5 via inversely regulating the expression of Twist1. Furthermore, dual Luciferase reporter assay confirmed the specifically binding of miR-16 to the predicted 3′-UTR of Twist1. The present study confirmed the pro-proliferative and pro-metastatic effect of PM2.5 on HCC cell line SMMC-7721. The possible mechanisms were EMT process induced by PM2.5 in SMMC-7721 cells, which was accompanied by a decrease in miR-16 and increase in Twist1 expression.
Dihydromyricetin attenuates inflammation through TLR4/NF-kappaB pathway
Authors: Jing Nianshui , Li Xinnan 
Published: September 2019

Abstract
Microglia plays a complex role in neuroinflammation, which has been implicated in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. This study aims to explore the effect and mechanism of Dihydromyricetin (DHM) on lipopolysaccharide (LPS)-induced inflammation in microglial BV-2 cells. Cell viability was measured by 3-[4,5-dimethylthiazol-2-yl]2,5-diphenyltetrazolium bromide (MTT) assay. The pro-inflammatory mediators and cytokines including interleukin (IL)-6, IL-1β, and tumor necrosis factor-α (TNF-α); inducible nitric oxide synthase (iNOS); and cyclooxygenase 2 (COX-2) were measured by enzyme-linked immunosorbent assay (ELISA) and/or quantitative real-time PCR (qRT-PCR). The expression of p-p65, p-IκBα, toll-like receptor 4 (TLR4), and myeloid differentiation primary response 88 (MyD88) were analyzed by western blot. The present study showed that DHM treatment alleviated LPS-induced viability reduction, suppressed the mRNA levels of IL-6, IL‐1β and TNF-α, inhibited the mRNA and protein expression of iNOS and COX-2, and attenuated the activation of NF-кB and TLR4 signaling in a concentration-dependent manner. In conclusion, DHM exerts an anti-inflammatory effect on LPS-induced BV-2 microglial cells, possibly through TRL4/NF-κB signaling pathway.
Disengagement in the Digital Age: A Virtue Ethical Approach to Epistemic Sorting on Social Media
Authors: Worden Kirsten J. 
Published: September 2019

Abstract
Using the Aristotelian virtue of friendship and concept of practical wisdom, this paper argues that engaging in political discourse with friends on social media is conducive to the pursuit of the good life because it facilitates the acquisition of the socio-political information and understanding necessary to live well. Previous work on social media, the virtues, and friendship focuses on the initiation and maintenance of the highest form of friendship (Aristotle’s ‘ideal friendship’) online. I argue that the information necessary to live well can come from non-ideal, civic friends in addition to ideal friends. In order to acquire this information successfully via social media, users should practice inclusive engagement, self-control, discretion, and audience-sensitivity in their cyber interactions. This argument is salient given the current concerns about ‘echo chambers’ or ‘filter bubbles’, in which users ignore or block out friends and news sources that support political perspectives different from one’s own.
Gate-tunable metafilm absorber based on indium silicon oxide
Authors: Zhao Hongwei , Zhang Ran , Chorsi Hamid T. , Britton Wesley A. , Chen Yuyao , Iyer Prasad P. , Schuller Jon A. , Negro Luca Dal , Klamkin Jonathan 
Published: September 2019

Abstract
In this work, reconfigurable metafilm absorbers based on indium silicon oxide (ISO) were investigated. The metafilm absorbers consist of nanoscale metallic resonator arrays on metal-insulator-metal (MIM) multilayer structures. The ISO was used as an active tunable layer embedded in the MIM cavities. The tunable metafilm absorbers with ISO were then fabricated and characterized. A maximum change in the reflectance of 57% and up to 620 nm shift in the resonance wavelength were measured.
Crystal structure of 2-butyl-6-(ethylamino)-1H-benzo[de]isoquinoline-1,3(2H)-dione, C18H20N2O2
Authors: Liu Peilian , Jiang Fangru , Huang Guiyuan , Sun Ying , Huang Liping 
Published: September 2019

Abstract
C18H20N2O2, monoclinic, C2/c (no. 15), a = 27.5693(13) Å, b = 8.3005(4) Å, c = 16.8797(8) Å, β = 127.0225(12)°, V = 3084.0(3) Å3, Z = 8, R
gt(F) = 0.0642, wR
ref(F
2) = 0.2248, T = 293(2) K.
MHD Peristaltic flow of a nanofluid in a constricted artery for different shapes of nanosized particles
Authors: Devaki Palluru , Venkateswarlu Bhumarapu , Srinivas Suripddi , Sreenadh Sreedharamalle 
Published: September 2019

AbstractMHD peristaltic transport of copper-water nanofluid in an artery with mild stenosis for different shapes of nanoparticles is studied in this paper. The exact solution is obtained for velocity, temperature and pressure gradient. The influence of all the parameters on velocity, temperature and pressure gradient is observed. The effect of stenosis plays a vital role in this paper, as it finds its application in the field of medicine. It is observed that the nanofluid flows rapidly in the presence of stenosis, which helps in destroying of the stencils soon. The shape of the nanoparticle is another important point to be concentrated due to based on the shape of the nanoparticle the fluid flow depends. The shape of the nanoparticle should be considered as bricks to increase the velocity, temperature and the pressure gradient. But a reversed behavior is observed if the shape of the nanoparticle is chosen as platelets. Streamlines are also concentrated and it is observed that there are more number of boluses if the shape of the nanoparticle is chosen as bricks. The effect of volume of the solid nanoparticle and stenosis warrants further study of the flow of nanofluids in tube and channel.
Efficient preparation of PDMS-based conductive composites using self-designed automatic equipment and an application example
Authors: Su Fengchun , Zhao Zhongli , Liu Ying , Si Wuyan , Leng Chong , Du Yu , Sun Jingyao , Wu Daming 
Published: September 2019

Abstract
In this paper, the fabrication process of polydimethylsiloxane (PDMS)-based microstructured conductive composites via differential temperature hot embossing was proposed based on the spatial confining forced network assembly theory. The mold temperature was kept constant throughout the whole embossing cycle in this method, whereas the setting temperatures of the upper and lower molds were different. To solve the problem of poor conveying performance, a double-station automatic hot embossing equipment was designed and developed. A “bullet-filled” accurate feeding system was designed aiming at the high viscosity and feeding difficulty of blended PDMS-based composites before curing. Dispersion mold and semifixed compression mold were designed according to different functional requirements of different workstations. The developed automatic hot embossing equipment had already been successfully applied to the continuous preparation of conductive composites with greatly improved processing precision and efficiency. Furthermore, the conductive composites with and without microstructures can be used as flexible sensors for pressure measurements.
Sustainable materials in automotive
Authors: Ryntz Rose , Kozora Susan 
Published: September 2019

Abstract
The use of plastic parts in the production of automobiles has a long and established history. In the more recent past, manufacturers have become interested in bio-based materials for a variety of parts, in part because they represent a more sustainable material stream, and in part because they may be more economically feasible. This chapter discusses the evolution from fossil fuel-based materials to bio-based materials in their established and potential uses for automotive parts.
Metrologie für heterogene Sensornetzwerke und Industrie 4.0
Authors: Eichstädt Sascha , Ludwig Björn 
Published: September 2019

Zusammenfassung
Netzwerke von Sensoren für verschiedene Messgrößen stellen zunehmend das Rückgrat für eine Vielzahl von Anwendungsgebieten in beispielsweise Industrie, Maschinenbau und Umweltüberwachung dar. Dabei spielt das Zusammenführen der Daten (Sensorfusion) eine zentrale Rolle in der Anwendung und ist im Allgemeinen ein gut untersuchtes Forschungsgebiet. Die Berücksichtigung metrologischer Grundprinzipien wie Kalibrierung, Messunsicherheiten und damit Rückführung auf das SI-Einheitensystem für vergleichbare und reproduzierbare Messergebnisse ist jedoch vergleichsweise wenig untersucht. Dieser Beitrag diskutiert Grundsatzfragen, stellt Lösungsansätze aus dem aktuell laufenden EMPIR-Projekt “Metrology for the Factory of the Future” (Met4FoF) vor und gibt einen Ausblick auf zukünftige Forschungsfelder. Dabei fokussiert sich der Artikel auf das Anwendungsfeld der sog. „Industrie 4.0“ als „Fabrik der Zukunft“.
Simplistic Synthesis and Enhanced Photocatalytic Performance of Spherical ZnO Nanoparticles Prepared from Arabinose Solution
Authors: Abdulkhair Babiker Y. , Salih Mutaz E. , Elamin Nuha Y. , Fatima A. MA. , Modwi A. 
Published: September 2019

Abstract
Strenuous efforts have been employed to prepare zinc oxide (ZnO) with eco-friendly methods; however, few studies have reported the fabrication of ZnO using a sustainable procedure. In this study, spherical ZnO nanoparticles were successfully fabricated for photocatalysis applications using a simple and eco-friendly method using an arabinose sugar solution. The ZnO nanoparticles with a wurtzite structure were obtained by combining zinc nitrate and arabinose in water, followed by heating, evaporation, and calcinations at different annealing temperatures. The annealed ZnO photocatalysts were characterised via X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). The findings revealed a hexagonal wurtzite structure and good crystallinity with crystallite size increasing from 18 to 31 nm by means of an increase in the annealing temperature. The photocatalytic performance was examined to determine the degradation of mix dye waste. The spherical ZnO nanoparticles showed mix pollutant degradation of 84 % in 25 min at 400 °C.
Study of the Absorption Properties of Terahertz Wave in the Plasma Medium
Authors: Liu Jian-Xiao , Meng Ling-Hui , Liu Yu-Jie , Feng Jun-Li , Yang Hong-Wei 
Published: September 2019

Abstract
In this article, we study about the absorption properties of terahertz (THz) wave in the magnetic plasma medium. Terahertz wave has strong transmission in plasma. Generally speaking, with the increase in THz wave frequency, the transmission in plasma is stronger. Thus, we can consider raising carrier frequency to THz band to solve the communication of “blackout.” We found that the absorption in magnetic plasma is greatly affected by magnetic field. The changes on the power absorption coefficient of the two kinds of eigen wave in magnetic plasma vary with how the outside magnetic field, incident angle, and the thickness of the plasma are obtained. The study found that following the increase in magnetic field, the absorption of left circularly polarised waves (L-wave) gradually reduces, and the right circularly polarised waves (R-wave) will produce two absorption peaks, and these two absorption peaks move to high frequency as a whole. With the increase in incident angle and the high spectrum absorption of L-wave enhancement, the reflection between the two absorption peaks of R-wave broadens. The reflection area on the left side of the low-frequency area to absorb has a little change. The absorption on the right side of the high-frequency area is enhancement. With the increase in the plasma thickness, the L-wave absorption peak on the right side of the high-frequency area absorbs enhancement; the R-wave reflection between the two absorption peak areas is impregnability, the second absorption peak absorption enhancement on the right side of the high-frequency area. The study has shown the different absorption mechanisms of the L-wave and the R-wave and shown different absorption features in magnetic plasma.