bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Fe2O3 addition and annealing on the mechanical and dissolution properties of MgO-and CaO-containing phosphate glass fibres for bio-applications
Authors: Tan Chao , Ahmed Ifty , Parsons Andrew J. , Zhu Chenkai , Betanzos Fernando B. , Rudd Chris D. , Liu Xiaoling 
Published: July 2018

Abstract
This paper investigated the preparation of phosphate glass fibres (PGFs) in the following systems: i) 45P2O5-5B2O3-5Na2O-(29-x)CaO-16MgO-(x)Fe2O3 and ii) 45P2O5-5B2O3-5Na2O-24CaO-(21-x)MgO-(x)Fe2O3 (where x = 5, 8 and 11 mol%) for biomedical applications. Continuous fibres of 23 ± 1 μm diameter were prepared via a meltdraw spinning process. Compositions with higher Fe2O3 content and higher MgO/CaO ratio required higher melting temperature and longer heating time to achieve glass melts for fibre pulling. The effects of Fe2O3 addition and annealing treatment on mechanical properties and degradation behaviours were also investigated. Adding Fe2O3 was found to increase the tensile strength from 523 ± 63 (Ca-Fe5) to 680 ± 75 MPa (Ca-Fe11), improve the tensile modulus from72 ± 4 (Ca-Fe5) to 78 ± 3 GPa (Ca-Fe11) and decrease the degradation rate from 4.0 (Mg-Fe5) to 1.9 × 10−6 kg m−2 s−1 (Mg-Fe11). The annealing process reduced the fibre tensile strength by 46% (Ca-Fe5), increased the modulus by 19.6%(Ca-Fe8) and decreased the degradation rate by 89.5% (Mg-Fe11) in comparison to the corresponding as drawn fibres. Additionally, the annealing process also impeded the formation of precipitate shells and revealed coexistence of the precipitation and the pitting corrosion as fibre degradation behaviours.
Differences in flowering sex ratios between native and invasive populations of the seagrass Halophila stipulacea
Authors: Nguyen Hung Manh , Kleitou Periklis , Kletou Demetris , Sapir Yuval , Winters Gidon 
Published: July 2018

Abstract
Deviations from the 1:1 sex ratio are common in dioecious plants. The tropical seagrass Halophila stipulacea is among an extremely rare group of dioecious plants that are widely recognized as female-biased. Here we report on differences in sex ratios between native (Eilat, northern Red Sea) and invasive (Cyprus, Mediterranean Sea) populations. While H. stipulacea populations were female-biased in their native region, invasive populations were either male- or female-biased. The existence of both sexes simultaneously in the Mediterranean invasive populations might help its ongoing expansion in the Mediterranean, thereby threatening local seagrasses species.
Commutability of the certified reference materials for the standardization of β-amyloid 1-42 assay in human cerebrospinal fluid: lessons for tau and β-amyloid 1-40 measurements
Authors: Andreasson Ulf , Kuhlmann Julia , Pannee Josef , Umek Robert M. , Stoops Erik , Vanderstichele Hugo , Matzen Anja , Vandijck Manu , Dauwe Martine , Leinenbach Andreas , Rutz Sandra , Portelius Erik , Zegers Ingrid , Zetterberg Henrik , Blennow Kaj 
Published: July 2018

AbstractBackground:The core Alzheimer’s disease cerebrospinal fluid (CSF) biomarkers total tau (T-tau), phosphorylated tau (P-tau), β-amyloid 1-42 (Aβ42) and β-amyloid 1-40 (Aβ40) are increasing in importance and are now part of the research criteria for the diagnosis of the disease. The main aim of this study is to evaluate whether a set of certified reference materials (CRMs) are commutable for Aβ42 and to serve as a feasibility study for the other markers. This property is a prerequisite for the establishment of CRMs which will then be used by manufacturers to calibrate their assays against. Once the preanalytical factors have been standardized and proper selection criteria are available for subject cohorts this harmonization between methods will allow for universal cut-offs to be determined.Methods:Thirty-four individual CSF samples and three different CRMs where analyzed for T-tau, P-tau, Aβ42 and Aβ40, using up to seven different commercially available methods. For Aβ40 and Aβ42 a mass spectrometry-based procedure was also employed.Results:There were strong pairwise correlations between the different methods (Spearman’s ρ>0.92) for all investigated analytes and the CRMs were not distinguishable from the individual samples.Conclusions:This study shows that the CRMs are commutable for the different assays for Aβ42. For the other analytes the results show that it would be feasible to also produce CRMs for these. However, additional studies are needed as the concentration interval for the CRMs were selected based on Aβ42 concentrations only and did in general not cover satisfactory large concentration intervals for the other analytes.
Detection capability of quantitative faecal immunochemical tests for haemoglobin (FIT) and reporting of low faecal haemoglobin concentrations
Authors: Fraser Callum G. , Benton Sally C. 
Published: July 2018

AbstractFaecal immunochemical tests for haemoglobin (FIT) are widely used in asymptomatic population screening for colorectal (bowel) cancer. FIT are also used to assist with the assessment of patients presenting with lower abdominal symptoms. Quantitative FIT allow the generation of numerical estimates of faecal haemoglobin (f-Hb) concentrations. There is now great interest in “low” f-Hb concentrations in these clinical settings: in consequence, knowledge of the detection capability is very important for f-Hb concentration examinations. There are a number of current problems associated with the reporting of low f-Hb concentrations and wide misunderstanding of the metrological aspects of examinations of f-Hb at low concentrations. These would be solved if the detectability characteristics of f-Hb concentration examinations, namely, the limit of blank (LoB), limit of detection (LoD) and limit of quantitation (LoQ), were generated, validated and used in reporting systems exactly as recommended in the EP17-A2 guideline of the Clinical Laboratory Standards Institute. LoB and LoD are statistical concepts, but the LoQ depends on definition of analytical performance specifications (APS). In this Opinion Paper proposals for interim APS are made, based on the current state of the art achieved with examinations of faecal samples. It is proposed that LoQ is determined at an examination imprecision of CV≤10% using faecal samples naturally positive for Hb rather than faeces spiked with haemolysate. Detailed proposals for reporting f-Hb data at low concentrations are also made.
Using superimposed multidimensional schemas and OLAP patterns for RDF data analysis
Authors: Hilal Median , Schuetz Christoph G. , Schrefl Michael 
Published: July 2018

Abstract
The foundations for traditional data analysis are Online Analytical Processing (OLAP) systems that operate on multidimensional (MD) data. The Resource Description Framework (RDF) serves as the foundation for the publication of a growing amount of semantic web data still largely untapped by companies for data analysis. Most RDF data sources, however, do not correspond to the MD modeling paradigm and, as a consequence, elude traditional OLAP. The complexity of RDF data in terms of structure, semantics, and query languages renders RDF data analysis challenging for a typical analyst not familiar with the underlying data model or the SPARQL query language. Hence, conducting RDF data analysis is not a straightforward task. We propose an approach for the definition of superimposed MD schemas over arbitrary RDF datasets and show how to represent the superimposed MD schemas using well-known semantic web technologies. On top of that, we introduce OLAP patterns for RDF data analysis, which are recurring, domain-independent elements of data analysis. Analysts may compose queries by instantiating a pattern using only the MD concepts and business terms. Upon pattern instantiation, the corresponding SPARQL query over the source data can be automatically generated, sparing analysts from technical details and fostering self-service capabilities.
Wahl maps and extensions of canonical curves and K⁢3K3 surfaces
Authors: Ciliberto Ciro , Dedieu Thomas , Sernesi Edoardo 
Published: July 2018

Abstract
Let C be a smooth projective curve
(resp.

(
S
,
L
)

{(S,L)}

a polarized

K
⁢
3

{K3}

surface)
of genus

g
⩾
11

{g\geqslant 11}

,
with Clifford index at least 3, considered in its canonical embedding in

ℙ

g
-
1

{\mathbb{P}^{g-1}}

(resp. in its embedding in

|
L
|

∨

≅

ℙ
g

{|L|^{\vee}\cong\mathbb{P}^{g}}

).
We prove that C (resp. S) is a linear section of an arithmetically
Gorenstein normal variety Y in

ℙ

g
+
r

{\mathbb{P}^{g+r}}

, not a cone, with

dim
⁡

(
Y
)

=

r
+
2

{\dim(Y)=r+2}

and

ω
Y

=

𝒪
Y

⁢

(

-
r

)

{\omega_{Y}=\mathcal{O}_{Y}(-r)}

, if the cokernel of the
Gauss–Wahl map of C
(resp.

H
1

⁡

(

T
S

⊗

L
∨

)

{\operatorname{H}^{1}(T_{S}\otimes L^{\vee})}

)
has dimension larger than or equal to

r
+
1

{r+1}

(resp. r). This relies on previous work of
Wahl and Arbarello–Bruno–Sernesi. We provide various applications.
DFT Study of Anthocyanidin and Anthocyanin Pigments for Dye Sensitized Solar Cells: Electron Injecting from the Excited States and Adsorption onto TiO2 (Anatase) Surface
Authors: Marcano Emildo 
Published: July 2018

Abstract
We explored, the absorption spectra, excited states and electronic injection parameters of anthocyanidin and anthocyanin pigments using the level of theory (TD)CAM-B3LYP/6–31 + G(d,p). For all isolated dyes, the distribution pattern of HOMO and LUMO spread over the whole molecules, which lead an efficient electronic delocalization. The calculated LHEs are all near unity. Methoxy group in Peonidin molecule lead the largest oscillator strength and LHE. The presence of water lead a higher spontaneous electronic inject process, with ΔGinject average of −1.14 eV. The ΔGinject order is Peonidin<Delphinidin<Cyanin<Cyanidin. Similarly, the adsorption energies (Eads) onto anatase surface model were obtained from level of theory GGA(PBE)/DNP. Eads of anthocyanin-(TiO2)30 complex was calculated to be from 17 to 24 eV, indicating both, the strong interactions between the dyes and the anatase (TiO2) surface and stronger electronic coupling strengths of the anthocyanin-(TiO2)30 complex, which corresponded to higher observed η. The HOMO and LUMO shape showed the electrons delocalized predominantly on the anthocyanin structure while, the LUMO + 1 shape is localized into the (TiO2)30 surface. Therefore we expected a electronic injection from HOMO to LUMO + 1 in the anthocyanin-(TiO2)30 adsorption complex, after the light absorption.
Synthesis and antimicrobial evaluation of 3-(4-arylthieno[2,3-d]pyrimidin-2-yl)- 2H-chromen-2-ones
Authors: Vlasov Sergiy V. , Kovalenko Sergiy M. , Shynkarenko Pavlo E. , Krolenko Konstantin Yu. , Vlasov Vitaliy S. 
Published: July 2018

Abstract
Syntheses of 3-(4-arylthieno[2,3-d]pyrimidin-2-yl)-2H-chromen-2-ones 5 by the reaction of 2-iminocoumarin-3-carboxamides 1 with (2-aminothiophen-3-yl)(aryl)methanones 2 and by the alternative Suzuki coupling of 4-chlorothieno[2,3-d]pyrimidin-2-yl-2H-chromen-2-one 7 with arylboronic acids were developed. Compound 5d showed higher antimicrobial activity against Staphylococcus aureus than the reference drug streptomycin.
Effects of lignin in wood on moisture sorption and hygroexpansion tested under dynamic conditions
Authors: Yang Tiantian , Ma Erni , Cao Jinzhen 
Published: July 2018

Abstract
Effects of lignin on dynamic sorption and hygroexpansion were investigated. Poplar wood (Populus cathay) [20×20×4 mm3 (radial×tangential×longitudinal)] was delignified at three levels and subjected to dynamic humidity changes, where the relative humidity (RH) changed sinusoidally between 45% and 75% at 25°C during 1, 6 and 24 h. Moisture contents (MC) and dimensional responses were recorded automatically. Scanning electron microscopy (SEM) results show that lignin was partly removed. MC and dimensions also varied sinusoidally with RH. At higher delignification levels, amplitudes, moisture sorption coefficients and humidity expansion coefficients became higher, but the phase lag displayed an opposite trend. The effects were due to the removal of the relatively hydrophobic lignin layers, in the course of which more hydroxyl groups of cellulose and hemicelluloses were accessible to humidity. A linear positive relation was found between the delignification rate and MC, and dimensional changes in the tangential direction. Lignin had a significant effect on sorption and hygroexpansion and this effect was greater for static sorption. Delignification reduced the hysteresis due to matrix stiffness decrement of wood, especially in the RH range of 55–65%.
Activation and activity of glycosylated KLKs 3, 4 and 11
Authors: Guo Shihui , Briza Peter , Magdolen Viktor , Brandstetter Hans , Goettig Peter 
Published: July 2018

Abstract
Human kallikrein-related peptidases 3, 4, 11, and KLK2, the activator of KLK3/PSA, belong to the prostatic group of the KLKs, whose major physiological function is semen liquefaction during the fertilization process. Notably, these KLKs are upregulated in prostate cancer and are used as clinical biomarkers or have been proposed as therapeutic targets. However, this potential awaits a detailed characterization of these proteases. In order to study glycosylated prostatic KLKs resembling the natural proteases, we used Leishmania (LEXSY) and HEK293 cells for secretory expression. Both systems allowed the subsequent purification of soluble pro-KLK zymogens with correct propeptides and of the mature forms. Periodic acid-Schiff reaction, enzymatic deglycosylation assays, and mass spectrometry confirmed the glycosylation of these KLKs. Activation of glycosylated pro-KLKs 4 and 11 turned out to be most efficient by glycosylated KLK2 and KLK4, respectively. By comparing the glycosylated prostatic KLKs with their non-glycosylated counterparts from Escherichia coli, it was observed that the N-glycans stabilize the KLK proteases and change their activation profiles and their enzymatic activity to some extent. The functional role of glycosylation in prostate-specific KLKs could pave the way to a deeper understanding of their biology and to medical applications.
Sphingolipids in early viral replication and innate immune activation
Authors: Bezgovsek Judith , Gulbins Erich , Friedrich Sarah-Kim , Lang Karl S. , Duhan Vikas 
Published: July 2018

Abstract
In this review, we summarize the mechanisms by which sphingolipids modulate virus multiplication and the host innate immune response, using a number of host-virus systems as illustrative models. Sphingolipids exert diverse functions, both at the level of the viral life cycle and in the regulation of antiviral immune responses. Sphingolipids may influence viral replication in three ways: by serving as (co)receptors during viral entry, by modulating virus replication, and by shaping the antiviral immune response. Several studies have demonstrated that sphingosine kinases (SphK) and their product, sphingosine-1-phosphate (S1P), enhance the replication of influenza, measles, and hepatitis B virus (HBV). In contrast, ceramides, particularly S1P and SphK1, influence the expression of type I interferon (IFN-I) by modulating upstream antiviral signaling and enhancing dendritic cell maturation, differentiation, and positioning in tissue. The synthetic molecule α-galactosylceramide has also been shown to stimulate natural killer cell activation and interferon (IFN)-γ secretion. However, to date, clinical trials have failed to demonstrate any clinical benefit for sphingolipids in the treatment of cancer or HBV infection. Taken together, these findings show that sphingolipids play an important and underappreciated role in the control of virus replication and the innate immune response.
Total yield of reactive species originating from an atmospheric pressure plasma jet in real time
Authors: Adhikari Ek R. , Samara Vladimir , Ptasinska Sylwia 
Published: July 2018

Abstract
It is now well established that plasma-induced reactive species are key agents involved in many biochemical reactions. This work reports on the formation of plasma reactive species in an acidified ferrous sulfate (Fricke) solution interacting with an atmospheric pressure plasma jet (APPJ). A yield of ferric (Fe3+) ions measured using in situ absorption spectroscopy was attributed to the formation of plasma reactive species provided and/or originated in the solution. The results indicated that the number of reactive species formed was proportional to plasma frequency and voltage. However, the Fe3+ yield per pulse decreased with increased frequency. To obtain a better understanding of the processes and species involved in the chemical reactions due to plasma exposure, Fe3+ yields were calculated and compared to the experimental data. At higher frequencies, there was insufficient time to complete all the reactions before the next pulse reached the solution; at lower frequencies, the Fe3+ yield was higher because of the relatively longer time available for reactions to occur. In addition, the comparison between DNA damage levels and Fe3+ yields was investigated under different experimental conditions in order to verify the usefulness of both the Fricke solution and the DNA molecule as a probe to characterize APPJs.
Health-promoting behaviors in nursing students: is it related to self-efficacy for health practices and academic achievement?
Authors: Farokhzadian Jamileh , Karami Abbas , Azizzadeh Forouzi Mansooreh 
Published: July 2018

Abstract

Background
Nursing students play a role in promotion of public health as health promoters and professional care providers. Therefore, health-promoting behaviors in nursing students and their self-efficacy for health practices are important in providing better services to patients and clients. With regard to the importance of these factors in the academic progress of students, this study was conducted to examine the level of health-promoting behaviors among nursing students and its relationship with self-efficacy for health practices and academic achievement.

Methods
This descriptive and correlational study was conducted on 217 nursing students of a large university of medical sciences in the south of Iran in 2016. Data were collected using the Persian version of the health promotion lifestyle profile (HPLP II), self-rated abilities for health practices scale (SRAHPS) and the grade point average of the students (levels A, B, C).

Results
The mean health-promoting behaviors (2.48 ± 0.35) and self-efficacy for health practices of the students (2.55 ± 0.62) were moderate. The mean score of the students’ academic achievement was at level B (16.02 ± 1.85). The health-promoting behaviors were significantly correlated with self-efficacy for health practices (r = 0.623, p < 0.0001) and academic achievement (r = 0.285, p < 0.0001). Moreover, self-efficacy for health practices was significantly correlated with academic achievement (r = 0.282, p < 0.0001).

Conclusion
The correlation between the health-promoting behaviors and health self-efficacy with academic achievement can be a good basis in devising health and educational programs for students. In planning for promoting academic achievement and health-promoting behaviors of students, it is essential to pay special attention to enhancement of self-efficacy for health practices.
Flexible IT platform for synchronizing energy demands with volatile markets
Authors: Schott Paul , Ahrens Raphael , Bauer Dennis , Hering Fabian , Keller Robert , Pullmann Jaroslav , Schel Daniel , Schimmelpfennig Jens , Simon Peter , Weber Thomas , Abele Eberhard , Bauernhansl Thomas , Fridgen Gilbert , Jarke Matthias , Reinhart Gunther 
Published: July 2018

Abstract
Abandoning fossil and nuclear energy sources in the long run and increasing amount of renewable energies in electricity production causes a more volatile power supply. Depending on external realities, renewable energy production emphasizes the need for measures to guarantee the necessary balance of demand and supply in the electricity system at all times. Energy intensive industry processes theoretically include high Demand Response potentials suitable to tackle this increasing supply volatility. Nevertheless, most companies do not operate their production in a flexible manner due to multiple reasons: among others, the companies lack know-how, technologies and a clear business case to introduce an additional level of flexibility into their production processes, they are concerned about possible impacts on their processes by varying the electricity demand and need assistance in exploiting their flexibility. Aside from fostering knowledge in industry companies, an IT-solution that supports companies to use their processes’ Demand Response potential has become necessary. Its concept must support companies in managing companies’ energy-flexible production processes and monetarize those potentials at flexibility markets. This paper presents a concept, which integrates both companies and energy markets. It enables automated trading of companies’ Demand Response potential on different flexibility markets.
Studying Firm Growth Distributions with a Large Administrative Employment Database
Authors: Dixon Jay , Petrunia Robert , Rollin Anne-Marie 
Published: July 2018

Abstract
This paper uses business tax administrative data to describe the annual firm growth rate distribution in Canada over the 2000–2009 period. This administrative tax database provides a unique lense to study firm growth as it allows us to look at the universe of Canadian employer firms and investigate the firm growth distribution across different dimensions. A non-normal, fat-tailed shape for the firm growth distributions holds across years, industries, regions, as well as firm size and age classes. The results show that the distributions of employment growth rates in Canada have more density in both the center and tails than a normal distribution. The evidence paints a picture of firm growth dynamics whereby most firms change very little each year, while a nontrivial amount also markedly grow or decline. A final finding is that young firms, aged four or less, represent a special case with an upwardly skewed distribution and a median growth rate greater than zero.
Development of a Two-Stage Segmentation-Based Word Searching Method for Handwritten Document Images
Authors: Malakar Samir , Ghosh Manosij , Sarkar Ram , Nasipuri Mita 
Published: July 2018

Abstract
Word searching or keyword spotting is an important research problem in the domain of document image processing. The solution to the said problem for handwritten documents is more challenging than for printed ones. In this work, a two-stage word searching schema is introduced. In the first stage, all the irrelevant words with respect to a search word are filtered out from the document page image. This is carried out using a zonal feature vector, called pre-selection feature vector, along with a rule-based binary classification method. In the next step, a holistic word recognition paradigm is used to confirm a pre-selected word as search word. To accomplish this, a modified histogram of oriented gradients-based feature descriptor is combined with a topological feature vector. This method is experimented on a QUWI English database, which is freely available through the International Conference on Document Analysis and Recognition 2015 competition entitled “Writer Identification and Gender Classification.” This technique not only provides good retrieval performance in terms of recall, precision, and F-measure scores, but it also outperforms some state-of-the-art methods.