bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual software defect prediction method based on improved recurrent criss-cross residual network
Authors: Chen Liqiong , Yunjie Lei , Huaiying Sun 
Published: November 2024

Purpose
This study aims to solve the problems of large training sample size, low data sample quality, low efficiency of the currently used classical model, high computational complexity of the existing concern mechanism, and high graphics processing unit (GPU) occupancy in the current visualization software defect prediction, proposing a method for software defect prediction termed recurrent criss-cross attention for weighted activation functions of recurrent SE-ResNet (RCCA-WRSR). First, following code visualization, the activation functions of the SE-ResNet model are replaced with a weighted combination of Relu and Elu to enhance model convergence. Additionally, an SE module is added before it to filter feature information, eliminating low-weight features to generate an improved residual network model, WRSR. To focus more on contextual information and establish connections between a pixel and those not in the same cross-path, the visualized red as integer, green as integer, blue as integer images are inputted into a model incorporating a fused RCCA module for defect prediction.

Design/methodology/approach
Software defect prediction based on code visualization is a new software defect prediction technology, which mainly realizes the defect prediction of code by visualizing code as image, and then applying attention mechanism to extract the features of image. However, the challenges of current visualization software defect prediction mainly include the large training sample size and low sample quality of the data, and the classical models used today are not efficient, and the existing attention mechanisms have high computational complexity and high GPU occupancy.

Findings
Experimental evaluation using ten open-source Java data sets from PROMISE and five existing methods demonstrates that the proposed approach achieves an F-measure value of 0.637 in predicting 16 cross-version projects, representing a 6.1% improvement.

Originality/value
RCCA-WRSR is a new visual software defect prediction based on recurrent criss-cross attention and improved residual network. This method effectively enhances the performance of software defect prediction.
The Pijao Indians in the Colombian Andes: a legacy for organizational democracy
Authors: Perilla Maluche Ricardo Benjamín 
Published: November 2024

Purpose
The purpose of this paper is to present the organizational and managerial practices of the Pijaos community as a segmentary organization located in the Colombian Andes, providing a cultural legacy through the effective management of power and authority, while establishing a bridge to organizational democracy (OD).

Design/methodology/approach
A review of books, papers and historiographies was conducted to collect historical data on the Pijaos.

Findings
It was found that the social organization of the Pijaos was devoid of power ambitions and abuses of authority, thanks to characteristics inherent in their economic system, parenting style, socio-political structure and authority based on rotation of leaders rather than supreme delegation under an inheritance scheme.

Originality/value
Management literature has not considered the ancestral Amerindian communities of the southern continent to rescue their organizational practices and relate them to the new management trends, as organizational democracy, which not only operates based on flat structures but also considers the rotation of individuals holding positions of power.
Presidential prerogative, congressional inaction, and the problem of presidential libraries
Authors: Guay Abigail 
Published: November 2024

Purpose
In the context of an analysis of stopgap and reactionary presidential library and records act, the purpose of this paper is to consider how the separation of the Obama Presidential Library from the Obama Presidential Center illuminates fundamental flaws in the public-private model that demand a more comprehensive legislative solution.

Design/methodology/approach
Drawing upon government, academic and public sources, this paper examines the legislation of presidential records and libraries to gain perspective on the presidential library system and the Obama Presidential Center, the first post-Presidential Records Act institution to operate independently of the National Archives and Records Administration (NARA).

Findings
This paper traces the evolution of presidential library statutes and standards to reveal how the genesis of an independent Obama Presidential Center strained an already stressed system, creating significant questions about its future.

Originality/value
This paper offers an original treatment of the statutes governing NARA’s administration of presidential libraries, framing a cycle of calls and responses, with the acts of individual presidents eliciting acts of Congress. Also original, and timely, is the treatment in this paper of how these laws created the conditions for an independent Obama Presidential Center.
Assessing vertical seed dispersal through seed oxygen isotope ratios of Japanese larch (Larix kaempferi)
Authors: Naoe Shoji , Ubukata Masatoshi , Tsunamoto Yoshihiro , Tayasu Ichiro 
Published: November 2024

AbstractVertical seed dispersal, involving seed movement to higher or lower elevations, plays a vital role in plant adaptation to rising temperatures. However, its assessment has been limited owing to labor‐intensive processes. A recently developed method exploits the negative correlation between elevation and seed oxygen isotope ratios (18O/16O; hereafter δ18O) for efficient evaluation of vertical seed dispersal. Nevertheless, it remains unclear whether this method is suitable for conifers and whether plant size and age introduce noise into δ18O values, which would affect vertical seed dispersal estimations. In this study, we investigated the association between elevation and seed δ18O values of Japanese larch (Larix kaempferi) and explored the relationship among these oxygen isotope ratios, tree height, diameter at breast height (DBH), and age. Notably, we found a negative correlation between elevation and seed δ18O values of L. kaempferi but failed to detect any influence of tree height, DBH, and age on these oxygen isotope ratios. These findings suggest this method's potential for accurately estimating vertical seed dispersal across diverse plant lineages.
Addressing (in)equity through public policy and local governance systems: A case study of Queensland, Australia
Authors: Reddel Tim , Lata Lutfun Nahar , Young Charlotte , Yates Miriam , McDaid Lisa 
Published: November 2024

AbstractEquity is a core social value that is widely debated in its conceptualisation and inclusion into policymaking and service delivery. Policymakers and street‐level actors often disagree about or have limited interest in defining (in)equity, leading to a lack of consensus about how to make measurable and long‐lasting impact for populations and communities experiencing disadvantage. Within this context, this paper draws on governance concepts such as hierarchy, market dimensions, and network dimensions to analyse key insights from in‐depth stakeholder interviews (N = 25) with government and non‐government actors in Queensland, Australia. The paper (1) examines the extent barriers to equity are created, reinforced, or reduced by centralised and street‐level public governance approaches and (2) determines what (and where) the opportunities are to address these barriers and build a systemic approach to achieve equity. The paper highlights important tensions for actors tackling issues of inequity, including centralised or distant policymakers and government and non‐government street‐level practitioners operating within disjointed systems for policy, delivery, and funding. Notwithstanding the increasingly prevalent ‘partnership’ narrative, the foundations remain anchored in policy and management practices that have been built on longstanding neo‐liberal market mechanisms or the ‘contract state’. A more integrated and adaptive approach that aligns high‐level policymaking with street‐level practitioners and local communities should be an important pillar in navigating these competing priorities and challenges.Points for practitioners
Equity is debated both conceptually and in policymaking and practice, leading to a lack of consensus about how to design and implement effective solutions.
Many universal policies and programs are designed and implemented in rigid silos, are not joined‐up, and have limited impact on the economic and social policy drivers of inequity and entrenched disadvantage.
A more adaptive and collaborative approach that aligns high‐level governance and policymaking with street‐level practitioners and local voices is possible but challenging to sustain.
The impact of a payer‐provider joint venture on healthcare value
Authors: Garabedian Laura F. , Wharam J. Frank , Newhouse Joseph P. , Lakoma Matthew , Argetsinger Stephanie , Zhang Fang , Galbraith Alison A. 
Published: November 2024

AbstractObjectiveTo examine how a novel payer‐provider joint venture (JV) between one payer and multiple competitive delivery systems in New Hampshire (NH), which included value‐based payment, care management, and non‐financial supports, impacted healthcare value and payer and provider group experiences.Study Setting and DesignWe conducted a mixed‐methods study. We used a quasi‐experimental longitudinal difference‐in‐differences design to examine the impact of the JV (which started in January 2016 and ended in December 2020) on healthcare utilization, quality, and spending, using members in Maine (ME) as a control group. We also analyzed patient uptake of the JV's care management program using routinely collected administrative data and assessed payer and provider group leaders' perspectives about the JV via semi‐structured interviews.Data Sources and Analytic SampleWe used administrative and claims data from 2013 to 2019 in a commercially insured population under 65 years in NH and ME. We also used administrative data on care management eligibility and uptake and conducted semi‐structured interviews with payer and provider group leaders affiliated with the JV.Principal FindingsThe JV was associated with no sustained change in medical utilization, quality, and spending throughout the study period. In the first year of the JV, there was a $142 (95% confidence interval: $41, $243) increase in pharmaceutical spending per member and a 13% (4.4%, 25%) relative increase in days covered for diabetes medications. Only 15% of eligible members engaged in care management, which was a key component of the JV's multi‐pronged approach. In a disconnect from the empirical findings, payer and provider group leaders believed that the JV reduced healthcare costs and improved quality.ConclusionsOur findings provide evidence for future payer‐provider JVs and demonstrate the importance of having a valid control group when evaluating JVs and value‐based payment arrangements.
Pharmacological inhibition of KSper impairs flagellar pH homeostasis of human spermatozoa
Authors: Ji Nanxi , Wang Xiaorong , Zeng Xuhui , Kang Hang 
Published: November 2024

AbstractBackgroundSperm‐specific potassium channel (KSper) comprised of pore‐forming subunit SLO3 and auxiliary subunit LRRC52 is of importance for sperm fertility. The deficiency of KSper in both mice and humans resulted in severe impairments of sperm functions including sperm hyperactivity and acrosome reaction. Previous reports suggested that mouse KSper modulated sperm function possibly by affecting sperm intracellular pH (pHi). However, the precise signaling mechanism of human KSper (hKSper) on the regulation of sperm functions was largely unclear.ObjectiveTo explore the regulatory role of hKSper on sperm flagellar pHi.Materials and methodsMore than 50 sperm donors were recruited during a period of 1 year. As reported in our previous work, we quantitatively measured flagellar pHi by employing a single‐cell pH fluorescent recording on human spermatozoa loaded with pH indicator pHrodo Red. Three different hKSper antagonists including clofilium, quinidine, and a polyclonal antibody of LRRC52 (LID1) were utilized to evaluate the effect of hKSper inhibition on sperm flagellar pHi.ResultsGiven the predominant role of hKSper on the regulation of membrane potential (Em), we first detected a considerable depolarization (about 25–30 mV) of Em evoked by clofilium and quinidine. Subsequently, it was shown that flagellar pHi values of human spermatozoa were significantly decreased by the treatment of clofilium (50 µM, from 7.13 ± 0.11 to 6.43 ± 0.12), quinidine (500 µM, from 7.00 ± 0.11 to 6.64 ± 0.08) and LID1 (20 µg/mL, from 6.98 ± 0.16 to 6.67 ± 0.22). Moreover, we found that when human spermatozoa were pre‐incubated with a high K+ solution (135 mM), both the depolarization of Em and the acidification of flagellar pHi evoked by clofilium and quinidine were abolished. In addition, we found that extracellular substitution of N‐methyl‐D‐glucamine for Na+ abolished pHi acidification induced by hKSper inhibition.Discussion and conclusionOur results demonstrate that hKSper inhibition evokes flagellar pHi acidification of human spermatozoa, suggesting that flagellar pHi maintenance is an important signaling mechanism of hKSper on the regulation of sperm functions.
Perinatal death in the Nordic countries in relation to gestational age: The impact of registration practice
Authors: Jeppegaard Maria , Frølich Maria Kongerslev , Thomsen Liv Cecilie Vestrheim , Heino Anna , Liu Eileen , Gunnarsdottir Johanna , Akerkar Rupali Rajendra , Eskildsen Lene Friis , Källén Karin , Ohlin Mikael , Klungsøyr Kari , Gissler Mika , Krebs Lone 
Published: November 2024

AbstractIntroductionAlthough perinatal death rates in the Nordic countries are among the lowest in the world, the risk of perinatal death is unevenly distributed across the Nordic countries, despite similarity in health care systems and pregnancy care. Birth registration practices across countries may explain some of the differences. We investigated differences in national registration of perinatal mortality within the Nordic countries and its impact on perinatal mortality according to gestational age.Material and MethodsEach country provided information by answering a questionnaire about registration of perinatal deaths. Furthermore, we collected aggregated count data based on Medical Birth Registries (MBR) from all Nordic countries in 2000 to 2021. Perinatal mortality was defined as stillbirth or neonatal death occurring within first 7 days of life. Data were grouped into six groups by gestational age (GA): extremely preterm (>28 + 0 weeks, subdivided into 22 + 0–23 + 6 and 24 + 0–27 + 6), very preterm (GA 28 + 0–31 + 6), moderate preterm (GA 32 + 0–33 + 6), late preterm (GA 34 + 0–36 + 6), term (GA 37 + 0–40 + 6) and late term or post‐term birth (GA ≥ 41 + 0). Perinatal mortality rate and risk ratio with 95% confidence intervals were calculated per country for each gestational age group. For Denmark, separate analyses included and excluded induced abortions.ResultsThe study included 6 343 805 live births, 22 727 stillbirths and 8932 liveborn infants who died within the first week of life after GA 22 + 0. Further 25 057 births were included with GA < 22 + 0, unknown GA and as a result of induced abortion. Overall, perinatal mortality rates decreased during year 2000–2021 in all Nordic countries. After exclusion of induced abortions, the perinatal mortality rate was similar in the five Nordic countries. The perinatal mortality rate for extremely preterm born infants was highest in Denmark, whereas the highest rate among infants born late term/post‐term was in Sweden.ConclusionsThe perinatal mortality rate in the Nordic countries is still decreasing, especially in the group of extremely preterm born infants. This study supports the need for further standardization of birth registration practices to ensure the validity of international comparisons.
AI as your ally: The effects of AI‐assisted venting on negative affect and perceived social support
Authors: Hu Meilan , Chua Xavier Cheng Wee , Diong Shu Fen , Kasturiratna K. T. A. Sandeeshwara , Majeed Nadyanna M. , Hartanto Andree 
Published: November 2024

AbstractIn recent years, artificial intelligence (AI) chatbots have made significant strides in generating human‐like conversations. With AI's expanding capabilities in mimicking human interactions, its affordability and accessibility underscore the potential of AI chatbots to facilitate negative emotional disclosure or venting. The study's primary objective is to highlight the potential benefits of AI‐assisted venting by comparing its effectiveness to venting through a traditional journaling platform in reducing negative affect and increasing perceived social support. We conducted a pre‐registered within‐subject experiment involving 150 participants who completed both traditional venting and AI‐assisted venting conditions with counterbalancing and a wash‐out period of 1‐week between the conditions. Results from the frequentist and Bayesian dependent samples t‐test revealed that AI‐assisted venting effectively reduced high and medium arousal negative affect such as anger, frustration and fear. However, participants in the AI‐assisted venting condition did not experience a significant increase in perceived social support and perceived loneliness, suggesting that participants did not perceive the effective assistance from AI as social support. This study demonstrates the promising role of AI in improving individuals' emotional well‐being, serving as a catalyst for a broader discussion on the evolving role of AI and its potential psychological implications.
Meta‐Analysis: Global Prevalence of Coeliac Disease in Type 1 Diabetes
Authors: Karimzadhagh Sahand , Abbaspour Elahe , Shahriarinamin Maryam , Shamsi Pourya , Poursadrolah Selvana , Khorasani Mehrdad , Daghighi Mahzad , Malek Arash , Talesh Jouan Taheri , Makharia Govind K. , Rostami‐Nejad Mohammad 
Published: November 2024

ABSTRACTBackgroundCoeliac disease (CD) is common in patients with type 1 diabetes (T1D), but prevalence varies globally due to differing screening protocols. There have been substantial changes in screening guidelines over the past two decades.AimTo evaluate CD prevalence in patients with T1D, focusing on screening studies using antitissue transglutaminase (anti‐tTG) antibody.MethodsWe searched PubMed, Web of Science, Embase and Scopus for studies published up to 11 December 2023 using keywords related to CD and diabetes. We used random‐effects models for overall prevalence and all subgroups, with heterogeneity assessed using Cochran's Q test and the I2 statistic performed in STATA 18.ResultsWe included 106 articles involving 65,102 T1D patients across 40 countries. The pooled CD seroprevalence and confirmed CD prevalence were 9% (95% confidence interval, CI, 8%–10%) and 6% (95% CI 5%–7%), respectively. The prevalence was higher in females and children. Denmark, Saudi Arabia and Libya exhibited the highest prevalence (11%), followed by India and Egypt (10%). Belgium, France, Germany, South Africa and the United States had the lowest prevalence (2%). High‐income countries showed significantly a lower CD prevalence than middle‐income countries (p = 0.03). Meta‐regression based on the Human Development Index (HDI) indicated that countries with higher HDI have lower seroprevalence and confirmed CD prevalence.ConclusionApproximately 1 in 16 patients globally and 1 in 12 patients in Asia and the Middle East with T1D has CD. We suggest that all patients with T1D should be screened for CD.
Link Between Social Relationships and Vulnerability Among Community‐Dwelling Older Adults Living Alone in Taiwan
Authors: Chen Ke‐Mei , Wang Shu‐Twu , Chao Shan‐Ru , Kasirisir Kui 
Published: November 2024

ABSTRACTThe study investigated the effect of social relationships on vulnerability among community‐dwelling older adults living alone in Taiwan. Data were extracted from the de‐identified service records of 2116 older adults living alone. Logistic regression models were used to identify the connection between social relationships and vulnerability. The results demonstrated that close social relationships help reduce vulnerability for older adults living alone. Moreover, the data indicated a statistically significant relationship between frailty and vulnerability and a statistically significant relationship between public assistance and vulnerability. An increase in the degree of frailty increases the risk of exposure to threats for older adults living alone. However, public assistance benefits older adults living alone. Existing policy and social work interventions aim to strengthen social safety nets for older adults living alone and establish social networks for older adults living alone through an institutional approach to prevent exposure to threats. Moreover, policymakers should focus not only on risk factors (e.g., frailty) but also on protective factors (e.g., social relationships and public assistance).
Population pharmacokinetic modelling of cetirizine concentrations in human breast milk—A contribution from the ConcePTION project
Authors: Melander Erik , Nielsen Elisabet I. , Lindqvist Annika , Hovd Markus , Gandia Peggy , Panchaud Alice , Guidi Monia , Annaert Pieter , Baranczewski Pawel , Spigset Olav , Nordeng Hedvig 
Published: November 2024

AbstractCetirizine is an antihistamine commonly used to treat allergic rhinitis and other allergic conditions. Cetirizine is often prescribed to breastfeeding mothers although there is limited information on infant exposure via breast milk. The aim of this study was to develop a popPK model based on data from a lactation study to predict cetirizine breast milk concentrations and estimate the relative infant dose (RID) in a breastfed infant. A popPK model was developed in NONMEM on data from a human lactation study including 35 women using cetirizine or levocetirizine while breastfeeding. Serial samples of breast milk were collected (n = 205) and the cetirizine concentrations quantified using a validated LC–MS/MS method. A one‐compartment model of cetirizine in breast milk was developed and employed to calculate the relative infant dose (RID). Covariates related to the maternal characteristics and breastfeeding patterns were evaluated in the model; only milk sampling pumping duration was found to be a significant covariate, with an increasing pumping duration leading to an increased apparent milk volume of distribution (Vm). The mean RID was 1.99% with the highest RID being 3.36% at Cmax. PopPK modelling could be used to estimate infant exposure to cetirizine via breast milk. The low predicted exposure in infants supports that cetirizine is compatible with breastfeeding.