bluuebunny/crossref_metadata_2025_split huggingface dataset:
Juventude e as novas tecnologias: problematizações acerca da escola contemporânea
Authors: Paixão Sergio Vale da 
Published: August 2019

O presente artigo tem como objetivo problematizar o papel da escola contemporânea e suas práticas de ensino considerando o atual e avançado contexto tecnológico em que os(as) jovens se encontram inseridos(as). Nossa consideração é de que sejam necessárias ressignificações na estrutura da escola bem como das práticas profissionais que levem em consideração o papel dos(as) estudantes(as) jovens produtores(as) de culturas e que, imersos(as) em suas produções culturais exigem da escola novas formas de ensinar e aprender. Para isso, acreditamos ser muito importante conceituar os termos adolescência e juventude para esclarecer sobre qual público nos interessa nessa proposta. Sendo assim, procuramos nos ancorar no conceito de juventude e de jovem para fortalecer nossa inclinação epistemológica e problematizar o ensino que acontece para esse público nas instituições escolares.
ESCRITA/REESCRITA ACADÊMICA NO ENSINO SUPERIOR: UM PROCESSO EM CONSTRUÇÃO PERMANENTE
Authors: Stockmanns Jussara Isabel 
Published: August 2019

A qualidade da produção dos textos acadêmicos de instituições de ensino superior é algo que preocupa docentes e discentes. Sabe-se que para que os textos resultem satisfatórios é necessário um longo processo de construção. Considerando a realidade de estudantes do IFPR Campus Palmas e suas necessidades, desenvolveu-se o projeto de extensão “Escrita/Reescrita acadêmica no Ensino Superior: um processo em construção permanente”, que tem por objetivo qualificar as produções escritas de trabalhos técnico-científicos dos estudantes da referida instituição de ensino. Para tanto, realizou-se uma sondagem sobre os conhecimentos prévios dos ingressantes no que tange às normas técnicas de elaboração de trabalhos acadêmicos, dando-se ênfase nas normas estabelecidas pela Associação Brasileira de Normas Técnicas (ABNT) e realizou-se reflexões sobre alguns questionamentos: Quais são as condições ofertadas para a efetivação de produções de cunho acadêmico na instituição? Quais critérios são considerados para sua elaboração e avaliação? Que tipo de orientações os estudantes recebem para uma escrita adequada ao meio em que se inserem? Esse conjunto de perguntas motivaram membros do Colegiado de Letras ao desafio de propor práticas de escrita e reescrita de textos com um grupo de participantes voluntários no projeto, ao considerar que a produção acadêmica faz parte da formação do discente, sendo prática que necessita ser estimulada e valorizada. Para a efetivação do projeto realizou-se pesquisa pesquisa bibliográfica e, posteriormente, pesquisa de campo, para a intervenção na realidade dos envolvidos. Embora ainda de caráter experimental e com resultados primários, o projeto se justifica e se destaca por vislumbrar a qualificação das produções escritas dos estudantes, o que, certamente, impactará positivamente em seu perfil acadêmico e profissional.
AS REPRESENTAÇÕES SOCIAIS DO IFPR SOB MÚLTIPLOS OLHARES – UM ESTUDO LONGITUDINAL
Authors: PRYJMA LEILA CLEURI 
Published: August 2019

Esta pesquisa, desenvolvida de forma longitudinal pelo Grupo de Pesquisa Representação Social, Subjetividade e Identidade busca encontrar a identidade do Instituto Federal do Paraná - Campus Pitanga, considerando identidade como resultado do processo de socialização, que compreende o cruzamento dos processos relacionais e biográficos (DUBAR, 1997) . Nesta conjuntura analisamos a representação social do IFPR a partir do aporte teórico-metodológico da Teoria das Representações Sociais proposta por Serge Moscovici (1961) e Jodelet (2001, 2007,2009) tendo como busca a Teoria do Núcleo Central (ABRIC, 1994, 2000). A busca desta representação foi feita em três categorias, sendo elas servidores, discentes e comunidade. Participaram deste estudo 12 docentes em 2016 e 17 em 2017, 60 alunos em 2016 e 125 em 2017, da categoria comunidade foram 68 participantes em 2016 e 59 em 2017. Utilizamos um Teste de Associação Livre de Palavras com o termo indutor “o IFPR é...” , solicitamos a hierarquização e a justificativa do 1º termo. O processo de análise das palavras evocadas foi organizado pela Ordem Média de Evocações e pela Ordem Média de Importância, utilizamos o software EVOC, realizamos a análise prototípica (Vèrges,2001), bem como os dados foram submetidos ao software IRAMUTEQ (Ratinaud, 2009) para a obtenção da análise de similitude e a criação da nuvem de palavras (metadado). Dentre as palavras mais evocadas pelos participantes destacam-se “oportunidade” e “conhecimento” comuns a todas as categorias. A alta frequência desses termos indicam o provável núcleo central, os pesquisadores compreendem as representações sociais do IFPR estão se formando ao longo dos anos em todas as categorias pesquisadas, fato comprovado na triangulação dos dados, observados na análise de similitude, na nuvem de palavras e no conteúdo das respostas.
EXAME DE SUFICIÊNCIA EM LÍNGUAS ESTRANGEIRAS NO CAMPUS PINHAIS DO INSTITUTO FEDERAL DO PARANÁ
Authors: Vieira Luciana Pereira Jasinski , Wojciechowski Thais 
Published: August 2019

Resumo:O projeto aqui relatado propôs-se a pesquisar uma forma viável e legal de valorização e validação do conhecimento prévio dos alunos nas disciplinas de Língua Inglesa e Língua Espanhola nos cursos técnicos integrados ao Ensino Médio do Campus Pinhais do Instituto Federal do Paraná. Partiu-se da premissa de que o reconhecimento de estudos anteriores faz-se necessário para evitar incompatibilidades entre alunos que já possuem certo grau de domínio da língua estrangeira e outros que ingressam no Ensino Médio com praticamente conhecimento algum. Com isso, almeja-se que professor execute seu trabalho com um nível mais uniforme entre os alunos, sem desmotivar os que são mais proficientes nem intimidar os que possuem menores recursos linguísticos. A metodologia de trabalho tomou por base a análise de leis e regimentos internos do Instituto, para assegurar a legalidade e viabilidade da proposta, assim como pesquisa sobre as instituições da rede em que o exame de suficiência já era prática habitual. Foi feita uma aplicação piloto da prova com uma aluna no início de 2017 e em 2018 a oportunidade foi aberta para os interessados de todo o campus. Foram realizadas avaliações escritas e orais, e dos 21 alunos de Língua Inglesa inscritos, 9 foram aprovados, tendo a opção de ser dispensados de cursar a disciplina no referido ano. Com relação à Língua Espanhola, houve apenas uma estudante inscrita, que não obteve aprovação. A divulgação dos procedimentos e conclusão desta iniciativa tem como intuito também auxiliar outras instituições que desejarem tornar o exame de suficiência uma prática regular, assim como abrir discussão sobre o tema, buscando otimizar o processo como um todo. Exame de suficiência em línguas estrangeiras no Campus Pinhais do Instituto Federal do Paraná
Linking water, society and ecology in a system dynamics framework: case study of Huainan city
Authors: Zhang Xiang , Wei Fangliang , Meng Yu , Xia Jun , Liu Jian , Xiao Yi 
Published: August 2019

Abstract
The nexus of water, society, and ecology is set to become a hotspot in the coming decades. In this paper, a simple model framework is developed to describe the interactions and feedback of the three categories of components within the regional water system. Taking Huainan City in Anhui Province of China as an example, a model is established with the system dynamics method to discuss its coevolution process. The results show that the development direction of Huainan City is consistent with the planning direction. The comprehensive effectiveness of the policies for developing water-saving technologies, supporting socio-economic development and ensuring food supply could be acceptable. Moreover, the improvements of water-saving technologies for agriculture and domestic water use need to be accelerated. The support for industrial development and the restrictions on pollutant emissions need to be strengthened. Therefore, the model could help decision-makers to understand the status of the water system, modify policies and make further planning. The coevolution of the regional water system is jointly dominated by the positive feedback loop aimed at productivity and the negative one aimed at sustainability.
Biocide resistant and antibiotic cross-resistant potential pathogens from sewage and river water from a wastewater treatment facility in the North-West, Potchefstroom, South Africa
Authors: Mann B. C. , Bezuidenhout J. J. , Bezuidenhout C. C. 
Published: August 2019

Abstract
Exposure to antibiotics, biocides, chemical preservatives, and heavy metals in different settings such as wastewater treatment plants (WWTPs) may apply selective pressure resulting in the enrichment of multiple resistant, co- and cross-resistant strains of bacteria. The purpose of this study was to identify and characterize potentially pathogenic triclosan (TCS) - and/or, chloroxylenol (PCMX) tolerant bacteria from sewage and river water in the North-West, Potchefstroom, South Africa. Several potential pathogens were identified, with Aeromonas isolates being most abundant. Clonal relationships between Aeromonas isolates found at various sampling points were elucidated using ERIC-PCR. Selected isolates were characterized for their minimum inhibitory concentrations against the biocides, as well as antibiotic resistance profiles, followed by an evaluation of synergistic and antagonistic interactions between various antimicrobials. Isolates were also screened for the presence of extracellular enzymes associated with virulence. High-performance liquid chromatography revealed the presence of both biocides in the wastewater, but fingerprinting methods did not reveal whether the WWTP is the source from which these organisms enter the environment. Isolates exhibited various levels of resistance to antimicrobials as well as several occurrences of synergy and antagonisms between the biocides and select antibiotics. Several isolates had a very high potential for virulence but further study is required to identify the specific virulence and resistance genes associated with the isolates in question.
Macrophage: A Key Therapeutic Target in Atherosclerosis?
Authors: Taghizadeh Eskandar , Taheri Forough , Renani Pedram G. , Reiner Željko , Navashenaq Jamshid G. , Sahebkar Amirhossein 
Published: August 2019

Background:Atherosclerosis is a chronic inflammatory disease and a leading cause of coronary artery disease, peripheral vascular disease and stroke. Lipid-laden macrophages are derived from circulating monocytes and form fatty streaks as the first step of atherogenesis.Methods:An electronic search in major databases was performed to review new therapeutic opportunities for influencing the inflammatory component of atherosclerosis based on monocytes/macrophages targeting.Results:In the past two decades, macrophages have been recognized as the main players in atherogenesis but also in its thrombotic complications. There is a growing interest in immunometabolism and recent studies on metabolism of macrophages have created new therapeutic options to treat atherosclerosis. Targeting recruitment, polarization, cytokine profile extracellular matrix remodeling, cholesterol metabolism, oxidative stress, inflammatory activity and non-coding RNAs of monocyte/macrophage have been proposed as potential therapeutic approaches against atherosclerosis.Conclusion:Monocytes/macrophages have a crucial role in progression and pathogenesis of atherosclerosis. Therefore, targeting monocyte/macrophage therapy in order to achieve anti-inflammatory effects might be a good option for prevention of atherosclerosis.
The Effects of L-Carnitine Supplementation on Serum Lipids: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Fathizadeh Hadis , Milajerdi Alireza , Reiner Željko , Kolahdooz Fariba , Chamani Maryam , Amirani Elaheh , Asemi Zatollah 
Published: August 2019

Background:
The findings of trials investigating the effects of L-carnitine administration on serum
lipids are inconsistent. This meta-analysis of randomized controlled trials (RCTs) was performed to summarize
the effects of L-carnitine intake on serum lipids in patients and healthy individuals.

Methods:
Two authors independently searched electronic databases including MEDLINE, EMBASE, Cochrane
Library, Web of Science, PubMed and Google Scholar from 1990 until August 1, 2019, in order to find relevant
RCTs. The quality of selected RCTs was evaluated using the Cochrane Collaboration risk of bias tool. Cochrane’s
Q test and I-square (I2) statistic were used to determine the heterogeneity across included trials. Weight mean
difference (SMD) and 95% CI between the two intervention groups were used to determine pooled effect sizes.
Subgroup analyses were performed to evaluate the source of heterogeneity based on suspected variables such as,
participant’s health conditions, age, dosage of L-carnitine, duration of study, sample size, and study location
between primary RCTs.

Results:
Out of 3460 potential papers selected based on keywords search, 67 studies met the inclusion criteria and
were eligible for the meta-analysis. The pooled results indicated that L-carnitine administration led to a significant
decrease in triglycerides (WMD: -10.35; 95% CI: -16.43, -4.27), total cholesterol (WMD: -9.47; 95% CI: -
13.23, -5.70) and LDL-cholesterol (LDL-C) concentrations (WMD: -6.25; 95% CI: -9.30, -3.21), and a significant
increase in HDL-cholesterol (HDL-C) levels (WMD: 1.39; 95% CI: 0.21, 2.57). L-carnitine supplementation did
not influence VLDL-cholesterol concentrations. When we stratified studies for the predefined factors such as
dosage, and age, no significant effects of the intervention on triglycerides, LDL-C, and HDL-C levels were found.

Conclusion:
This meta-analysis demonstrated that L-carnitine administration significantly reduced triglycerides,
total cholesterol and LDL-cholesterol levels, and significantly increased HDL-cholesterol levels in the pooled
analyses, but did not affect VLDL-cholesterol levels; however, these findings were not confirmed in our subgroup
analyses by participant’s health conditions, age, dosage of L-carnitine, duration of study, sample size, and study
location.
The Role of Vascular Aging in Atherosclerotic Plaque Development and Vulnerability
Authors: Liberale Luca , Camici Giovanni G. 
Published: August 2019

Background:The ongoing demographical shift is leading to an unprecedented aging of the population. As a consequence, the prevalence of age-related diseases, such as atherosclerosis and its thrombotic complications is set to increase in the near future. Endothelial dysfunction and vascular stiffening characterize arterial aging and set the stage for the development of cardiovascular diseases. Atherosclerotic plaques evolve over time, the extent to which these changes might affect their stability and predispose to sudden complications remains to be determined. Recent advances in imaging technology will allow for longitudinal prospective studies following the progression of plaque burden aimed at better characterizing changes over time associated with plaque stability or rupture. Oxidative stress and inflammation, firmly established driving forces of age-related CV dysfunction, also play an important role in atherosclerotic plaque destabilization and rupture. Several genes involved in lifespan determination are known regulator of redox cellular balance and pre-clinical evidence underlines their pathophysiological roles in age-related cardiovascular dysfunction and atherosclerosis.Objective:The aim of this narrative review is to examine the impact of aging on arterial function and atherosclerotic plaque development. Furthermore, we report how molecular mechanisms of vascular aging might regulate age-related plaque modifications and how this may help to identify novel therapeutic targets to attenuate the increased risk of CV disease in elderly people.
Diabetes and Vascular Disease: Is It All About Glycemia?
Authors: Vecchié Alessandra , Montecucco Fabrizio , Carbone Federico , Dallegri Franco , Bonaventura Aldo 
Published: August 2019

Background:
Diabetes is increasing over time, mainly driven by obesity, aging, and urbanization.
Classical macro- and microvascular complications represent the final result of a complex interplay involving
atherosclerosis at all stages.

Methods:
In this review, we aim at focusing on current updates in the pathophysiology of vascular disease in
diabetes and discussing how new therapies might influence the management of these patients at high cardiovascular
risk. Diabetes shows accelerated atherosclerosis with a larger inflammatory cell infiltrate, thus favoring the
development of heart failure. ‘Diabetic cardiomyopathy’ perfectly describes a specific ischemia- and hypertension-
independent entity due to diabetes-related metabolic alterations on myocardial function. Moreover, platelets
from subjects with diabetes display a typical hyperreactivity explaining the stronger adhesion, activation, and
aggregation. Additionally, diabetes provokes an exaggerated stimulation of the endothelium, with an increased
release of reactive oxygen species and a reduced release of nitric oxide, both key elements of the endothelial
dysfunction. Also, the coagulation cascade and leukocytes activate contributing to this pro-thrombotic environment.
Neutrophils have been recently recognized to play a pivotal role by releasing neutrophil extracellular traps.
Finally, microparticles from platelets, neutrophils or monocytes are detrimental effectors on the vessel wall and
are involved both in vascular dysfunction and in thrombotic complications.

Conclusion:
In light of these findings, the therapeutic management of diabetes needs to be mostly focused on
limiting the progression of complications by targeting precise pathophysiological mechanisms rather than the
mere glycemic control, which failed to markedly reduce the risk for macrovascular complications and mortality.
Withdrawal Notice: Transformation of Cyanothioformanilides into Halogenated and Alkylated Imidazolidineiminothione Derivatives and Evaluation of Antibacterial and Antifungal Activities
Authors: Sh. El-Sharief Marwa A. M. , Al-Harbi Reem A. K. , Abbas Samir Y. , El-Gammal Eman W. , El-Sharief Ahmed M. Sh. 
Published: August 2019

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The Impact of Tracheostomy Timing on the Duration and Complications of Mechanical Ventilation
Authors: Zaponi Renata de Souza , Osaku Erica Fernanda , Abentroth Lilian Regina Lengler , Marques da Silva Mayara Manzoni , Jaskowiak Jaiane Luiza , Ogasawara Suely Mariko , Leite Marcela Aparecida , de Macedo Costa Cláudia Rejane Lima , Porto Itamar Regazzo Pedreschi , Jorge Amaury Cezar , Duarte Pericles Almeida Delfino 
Published: August 2019

Background:
Mechanical ventilation is a life support for ICU patients and is indicated in
case of acute or chronic respiratory failure. 75% of patients admitted to ICU require this support and
most of them stay on prolonged MV. Tracheostomy plays a fundamental role in airway management,
facilitating ventilator weaning and reducing the duration of MV. Early tracheostomy is defined when
the procedure is conducted up to 10 days after the beginning of MV and late tracheostomy when the
procedure is performed after this period. Controversy still exists over the ideal timing and
classification of early and late tracheostomy.

Objective:
Evaluate the impact of timing of tracheostomy on ventilator weaning.

Method:
Single-center retrospective study. Patients were divided into three groups: very early
tracheostomy (VETrach), intermediate (ITrach) and late (LTrach): >10 days.

Results:
One hundred two patients were included: VETrach (n=21), ITrach (n=15), and LTrach
(n=66). ITrach group had lower APACHE II (p=0.004) and SOFA (p≤0.001). Total ICU length of
stay, and incidence of post-tracheostomy ventilator-associated pneumonia were significantly lower in
the VETrach and ITrach groups. The GCS and RASS scores improved in all groups, while the
maximal inspiratory pressure and rapid shallow breathing index showed a tendency towards
improvement on discharge from the ICU.

Conclusion:
Very early tracheostomy did not reduce the duration of MV or length of ICU stay after
the procedure when compared to late tracheostomy, but was associated with low rates of ventilatorassociated
pneumonia. Neurological patients benefitted more from tracheostomy, particularly very
early and intermediate tracheostomy.
Neural Direct Torque Control for Induction Motor under Voltage Source Inverter Open Switch Fault
Authors: Kadri Farid , Hamida Mohamed A. 
Published: August 2019

Background:
The study of induction motor behavior during abnormal conditions due to
the presence of faults and the possibility to diagnose these abnormal conditions has been a challenging
topic for many electrical machine researchers.

Objective:
Direct Torque Control (DTC) is applied to the control of an induction motor in healthy
and an open circuit fault in the PWM three phase voltage fed inverter. Neural DTC is developed
and used to improve the dynamic behavior of the drive system under faulty switch occurrence.

Methods:
The validity of the proposed control scheme is tested under normal conditions and
switching fail in the Voltage Source Inverter (VSI) caused by an open circuit. Through a simulation
testing of an induction motor drive system at different speed references, a comparison between
basic DTC and Neural DTC is performed.

Results:
Simulated results on 1.5-kW induction motor drive show the performance of the proposed
control in normal and faulty cases. The stator current, flux, torque, and speed at different references
are determined and compared in the above techniques using MATLAB-SIMULINK.

Conclusion:
A Neural Network (NN) DTC control system under an open switch fault is proposed
without the need for classical switching table. The use of hybrid intelligent techniques aims to improve
the DTC performances in case of multiple faults occurrence.