bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effective Methodologies for Enhancing Cloud Management in New Modern Enterprises
Authors: Aruna L. 
Published: June 2018

Today Cloud computing is altering the way industries and enterprises do their businesses in that with passion scalable and virtualized assets are provided as a service over the Internet. This new model creates a brand new chance for enterprises. In this paper, some of the essential features of effective methodologies for cloud computing in the modern enterprise are briefly discussed with regard to the end-users, enterprises that use the cloud as a platform, and cloud providers themselves. Cloud Computing is capable as one of the main enablers for the all new manufacturing industry, it can transform the usual manufacturing business model, help it to align product innovation with business strategy, and create intelligent factory networks that support successful collaboration. Cloud computing has been in some of the major key areas of manufacturing industries such as IT, pay-as-you-go business models, productions calling up and down per require, and elasticity in deploying and customizing solutions. Clients can use cloud services according to their requirements. Cloud users can request services ranging from product design, manufacturing, testing, management, and all others tags of a product life cycle. Cloud Managed service provider (CMSP) is a company that distantly manages a customer's IT communications and/or end-user systems, typically on a proactive basis and under a subscription model.
Hubsm: A Novel Amino Acid Substitution Matrix for Comparing Hub Proteins
Authors: G. Renganayaki , Nair Achuthsankar S. 
Published: June 2018

Sequence alignment algorithms and database search methods use BLOSUM and PAM substitution matrices constructed from general proteins. These de facto matrices are not optimal to align sequences accurately, for the proteins with markedly different compositional bias in the amino acid. In this work, a new amino acid substitution matrix is calculated for the disorder and low complexity rich region of Hub proteins, based on residue characteristics. Insights into the amino acid background frequencies and the substitution scores obtained from the Hubsm unveils the residue substitution patterns which differs from commonly used scoring matrices .When comparing the Hub protein sequences for detecting homologs, the use of this Hubsm matrix yields better results than PAM and BLOSUM matrices. Usage of Hubsm matrix can be optimal in database search and for the construction of more accurate sequence alignments of Hub proteins.
Control Cloud Data Access Privilge Anonymity with Attributed Based Encryption
Authors: Sudheer P. , Surekha T. Lakshmi 
Published: June 2018

Cloud computing is a revolutionary computing paradigm, which enables flexible, on-demand, and low-cost usage of computing resources, but the data is outsourced to some cloud servers, and various privacy concerns emerge from it. Various schemes based on the attribute-based encryption have been to secure the cloud storage. Data content privacy. A semi anonymous privilege control scheme AnonyControl to address not only the data privacy. But also the user identity privacy. AnonyControl decentralizes the central authority to limit the identity leakage and thus achieves semi anonymity. The Anonymity –F which fully prevent the identity leakage and achieve the full anonymity.
An Automated Brain Tumor Detection in MRI using Firefly Optimized Segmentation
Authors: Kaur Prabhjot , Kaur Amardeep 
Published: June 2018

In the medical field brain tumor detection is an important application. The existing techniques of segmentation has various limitations. Existing techniques ignored the medical images which have poor quality or low brightness. Segmentation becomes the challenging issue as the image contains non-uniform object texture, cluttered objects, different image content and image noise. New technique of segmentation is proposed by research to detect tumor from MR images using firefly algorithm, then tumor is segmented and its features are extracted from MR image. The main goal of Research to design an algorithm for MRI based brain tumor segmentation using firefly algorithm and to improve the accuracy of the tumor detection. Fireflies produce a reaction in their body which produce light , this chemical reaction is called bioluminescent. By using firefly technique it is possible to detect and localize tumor accurately. For comparative analysis, various parameters are used to demonstrate the superiority of proposed method over the conventional ones.
Prevention of Gray Hole Attack Using ABC and Fuzzy Logic
Authors: Singh Lokeshwar , Sharma Ashish 
Published: June 2018

There are many advantages and reasons for wireless sensor network to be popular. The key concern while establishing wireless sensor network (Mobile ad-hoc network) is the routing protocol to be applied. Routing process is the process of discovering the path that a data packet will follow to get it from the source node to the destination node. As the mobile ad-hoc network consists of mobile nodes with no controlling unit in which each and every step of communication is handled by the nodes within the network itself. The selection of routing protocol is one of the difficult tasks and the key challenge faced by the routing is the energy consumption issue apart from the others. In this research, the routing technique is developed with a basic focus on reduction of the energy consumption while improving the overall performance of the network. Presently, various efficient routing protocols have been estimated for wireless sensor network. In the presence of malicious nodes, the network becomes penetrable to different kind of attacks. In wireless sensor network, routing-attacks are relatively serious. It has number of potential-applications in completely un-predictable in dynamic environment. Routing protocol utilized here are in a form of reactive-routing protocol known as OLSR. This routing protocol route is based on demand.The proposed work has designed and implemented wireless sensor network in OLSR routing protocol. The gray hole attack is mitigated using Fuzzy Logic based on rule sets to have better routing process and ABC (Artificial Bee Colony) algorithm at superior rate for optimizing the route set at novel objective function. In this work, the performance analysis of the network with the scenarios consisting 50 nodes moving with the speed of the 5-10m/s within the area (1000X1000) m2 has been done in regards to the parameters, namely, Throughput, End-to-End Delay, BER (bit error rate) and Energy consumption).
Cyber Security in Smart Grid System
Authors: Jaysawal Anoop 
Published: June 2018

Abstract: The smart grid is an evolution of the electrical grid to respond to these challenges. A smart grid is an energy transmission and distribution network enhanced through digital control, monitoring, and telecommunications capabilities. It provides a real-time, two-way flow of energy and information to all stakeholders in the electricity chain, from the generation plant to the commercial, industrial, and residential end user. This evolution is crucial for integrating both renewable and distributed energy resources and to improve the efficiency and sustainability of the electrical grid and associated services. It will also help in other ways, such as enabling:• Smart and positive energy infrastructures• Increased energy density management during peaks• Real-time pricing to customers• Integrated mobility services• New virtual power plants• Micro grid
DIGITAL PHILOSOPHY
Authors: Sadiku Matthew N. O. , Tembely Mahamadou , Musa Sarhan M. 
Published: June 2018

The digital revolution has had profound effects on the society in general and on philosophy in particular. Digital philosophy is part of the emerging field of digital humanities. It is transforming some of previously unquestioned philosophical concepts of belief, experience, knowledge, intelligence, cognition, value, truth, reality, and responsibility, and privacy. This paper provides a brief introduction into digital philosophy.
Uso de la técnica CLARITY para la identificación de marcadores fluorescentes en cortes gruesos de la médula espinal
Authors: Sisti María Susana , Nishida Fabián , Zanuzzi Carolina N , Portiansky Enrique Leo 
Published: June 2018

El estudio de las interconexiones que establecen las neuronas entre sí o con las células de la glía es uno de los mayores desafíos de la neurociencia. Los anticuerpos fluorescentes permiten la identificación y localización de diferentes estructuras tisulares. Sin embargo, su uso eficiente requiere de la utilización de cortes delgados de muestras, que constituyen una limitación para el estudio de las interconexiones en el sistema nervioso. Asimismo, un mayor espesor de la muestra limita la penetración de la luz emitida por el microscopio, mientras que la opacidad propia del tejido nervioso debida a su alto contenido lipídico dificulta la adquisición de las imágenes al restringir la resolución de los objetos. La técnica CLARITY (del inglés, Clear, Lipidexchanged, Acrylamidehybridized Rigid, Imaging/Immunostaining/In situ hybridizationcompatible, Tissue hYdrogel) permite subsanar estos inconvenientes. Esta técnica fue adaptada en nuestro laboratorio para el estudio de la médula espinal de rata. De acuerdo con el procedimiento realizado, pudimos obtener un órgano completamente translúcido, estructuralmente intacto y que permitió su procesamiento mediante técnicas de inmunofluorescencia y de lectinhistoquímica sin mayores dificultades. A partir de muestras de más de 1 mm de espesor se obtuvieron imágenes confocales de gran resolución y de mayor penetrabilidad que las que se obtienen utilizando las técnicas de procesamiento convencionales. La implementación de esta técnica en nuestro laboratorio permitirá optimizar la información obtenida a partir de muestras de interés.
Basic and clinical research progress in acute lung injury/acute respiratory distress syndrome
Authors: Wang Tong 
Published: July 2018

Abstract
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is an acute progressive respiratory failure caused by severe infection, trauma, shock, poisoning, inhaled harmful gas, acute pancreatitis, and pathological obstetrics. ALI and ARDS demonstrate similar pathophysiological changes. The severe stage of ALI is defined as ARDS. At present, a significant progress has been achieved in the study of the pathogenesis and pathophysiology of ALI/ARDS. Whether or not ALI/ARDS patients can recover depends on the degree of lung injury, extra-pulmonary organ damage, original primary disease of a patient, and adequacy in supportive care. Conservative infusion strategies and protective lung ventilation reduce ARDS disability and mortality. In this study, the pathogenesis of ALI/ARDS, lung injury, molecular mechanisms of lung repair, and conservative infusion strategies and pulmonary protective ventilation are reviewed comprehensively.
Research progress on anti-infection therapy for sepsis in children
Authors: Lu Guoxiu 
Published: July 2018

Abstract
Sepsis is a systemic inflammatory response caused by infection and a critical illness in pediatrics. This disease is the leading cause of death in infants and children worldwide. An early, appropriate, and adequate anti-infective treatment can effectively prevent disease progression and improve the survival rate of children. However, antimicrobial drug abuse, increased drug-resistant bacteria, and lack of epidemiological data have hampered the effective and rational anti-infective treatment of patients with sepsis and enhancement of the success rate of rescue, especially for children. This article briefly reviews the recent advances in anti-infective treatment for sepsis in children at home and abroad based on sepsis definition, pathogen distribution and drug resistance, infection source control, and rational anti-infection. The results provide a foundation for clinical treatment of sepsis.
Research progress in urinary tract infection and its therapeutic drugs
Authors: Gu Xiaoming 
Published: July 2018

AbstractObjectiveThe objective of this study was to understand the pathological mechanism and therapeutic progress in the study of urinary tract infections to provide references for clinical diagnosis and identification and development of therapeutic drugs.MethodsWe summarized the types, pathological mechanisms, and therapeutic drugs for urinary tract infections on the basis of recent publications on these infections, both domestic and abroad.Results and conclusionsUrinary tract infection is mainly caused by pathogenic bacterial infection and treated by targeting bacterial adhesion, bacterial toxin, protease, urease, and siderophores, as well as using pili as vaccines and small-molecule drugs. Vaccines that target bacterial adhesion can block well the interaction between pathogens and the body, thereby reducing the incidence of urinary tract infections. The clinical efficacy of vaccines targeting bacterial toxins and proteases needs further evaluation. Vaccines targeting iron carriers retard disease progression and attenuate bacterial colonization. Urease-targeted small-molecule drugs exhibit certain curative effects and serious side effects. Small pili-targeted drugs can prevent and treat urinary tract infections by blocking the colonization and invasion of pathogens in animal models of urinary tract infections on the bladder. Adhesive FimH antibodies have entered Phase I clinical trials. However, pilicides, mannosides, and vaccines that target pili, iron carriers, and other virulence factors are still in the experimental or preclinical stages of research.
Hospital staff’s risk of developing musculoskeletal disorders, especially low back pain
Authors: Hafner Nataša Dernovšček , Milek Damjana Miklič , Fikfak Metoda Dodič 
Published: June 2018

Abstract

Introduction
Health-related absenteeism impacts individuals, companies, and society. Its consequences are reflected in the cost of benefits, substitutes, and reduced productivity. Research shows that musculoskeletal disorders (MSDs) are the most common work-related health problem reported by hospital staff. This study determines the groups at the Ljubljana University Medical Centre that are most susceptible to MSDs, especially low back pain.

Methods
Using data from the Health Data Centre of the Slovenian National Public Health Institute and the medical centre, this cross-sectional study analysed absenteeism among medical centre employees. The correlation between MSD / low-back pain risk factors and incidence was determined using logistic regression. An odds ratio was calculated to determine the probability of MSDs, most especially low back pain via sex, age, occupation, and education.

Results
Sick leave at the medical centre is higher than 5%, exceeding the Slovenian healthcare sector average. MSDs, as the main reason for absence, is significantly more frequent in women, non-medical staff, and employees with a maximum secondary school education. Among the MSDs, low back pain predominates as a reason for absence and is most frequent among nurses, midwives, and employees of 20 to 44.9 years old.

Conclusion
This study offers insight into the health status of medical centre employees. The high percentage of sick leave is mainly due to musculoskeletal disorders, including low back pain. This is an important basis for further monitoring and analysis of sick leave indicators and for planning systematic and continuous workplace health-promoting measures to manage ergonomic risk factors and reduce health-related absenteeism.
The role of a school nurse in the care of a child with diabetes mellitus type 1 - the perspectives of patients and their parents: Literature review
Authors: Stefanowicz Anna , Stefanowicz Joanna 
Published: June 2018

Abstract

Introduction
The aim of this literature review was to explore the views of parents and children with type 1 diabetes mellitus regarding having a school nurse.

Methods
Six databases were selected for the analysis. The research strategy was based on the PICO model. The research participants were children with type 1 diabetes mellitus and/or their parents.

Results
The present review of research papers includes 12 publications. The majority of works deal with the perspectives of children with type 1 diabetes and their parents on various aspects related to the role of a school nurse in the care of a child with type 1 diabetes:

the presence of a school nurse;

the role of a school nurse in the prevention and treatment of hypoglycaemia, in performing the measurements of blood glucose, and in insulin therapy;

the role of a nurse in improving metabolic control of children with type 1 diabetes;

a nurse as an educator for children with type 1 diabetes, classmates, teachers, teacher’s assistants, principals, administrators, cafeteria workers, coaches, gym teachers, bus drivers, and school office staff;

a nurse as an organiser of the care for children with type 1 diabetes.

Conclusions
According to parents and children with type 1 diabetes mellitus, various forms of school nurse support (i.e., checking blood glucose, giving insulin, giving glucagon, treating low and high blood glucose levels, carbohydrate counting) are consistently effective and should have an impact on the condition, improvement of metabolic control, school activity and safety at school.
Bir Yeşil İguanada (Iguana Iguana) Metastatik Kalsifikasyonlar ile Karakterize Metabolik Hastalık
Authors: İPEK Volkan , MUTLU Ayşe Meriç , AKKOÇ Ahmet , ÖZYİĞİT M. Özgür 
Published: June 2018

Esaret altındaki sürüngenlerde böbrek hastalıkları
oldukça yaygındır ve ölümlerinin birincil sebebidir. Bakıcı yönetiminden ve
beslenmeden kaynaklanan metabolik hastalıklar böbrek hastalıkların
şekillenmesinde önemli bir yer tutar. Bu metabolik hastalıklar orta yaşlı yeşil
iguanalarda diyetteki kalsiyum/fosfor oranındaki dengesizlikler nedeni ile
oluşan kilo kaybı, anoreksi ve soluk müköz membranlarla karakterizedir.
Metabolik hastalığın kronikleştiği durumlarda ise belirgin dehidrasyon, ileri
derecede böbrek yetersizliği ve metastatik kalsifikasyonlar gözlenebilir. Sunulan
bu olguda hayvanat bahçesinde barındırılan yetişkin bir yeşil iguanada, idrar
kesesi içerisinde yaklaşık 3 cm çaplı, beyaz renkli ve sert kıvamlı bir taşın
bulunduğu gözlendi. Böbreklerin kıvamının oldukça sertleşmiş olduğu ve
yüzeylerinin pürüzlü bir görünüm aldığı dikkati çekti. Mikroskobik incelemede,
böbrek korteks ve medullasının diffuz bir şekilde yıkımlandığı; belirgin
fibrozis ile birlikte interstisyel alanda yaygın kalsifikasyonların da
bulunduğu gözlendi. Mide mukozasında
yaygın nekrotik sahaların oluştuğu ve bu nekrotik sahaların şekillenen
kalsifikasyona bağlı olarak mavimsi bir renkte boyandığı dikkati çekti. Ayrıca
akciğerlerde interstisyel alanlarda ve pankreasta da parankimal damarlarda
kalsifikasyonların şekillendiği görüldü.
Köpeklerde sevofloran ile oluşturulan inhalasyon anestezi öncesinde ksilazin-ketamin ya da propofol kullanımının postoperatif ağrı üzerine etkinliklerinin karşılaştırılması
Authors: Ermutlu Celal Şahin 
Published: June 2018

Bu
çalışmada sevofloran gaz anestezisi için ksilazin-ketamin kombinasyonu veya
propofol ile sağlanan indüksiyonların postoperatif analjezi üzerine etkilerinin
karşılaştırılması amaçlandı. Hayvan materyalini ekstremite kırığı ile
kliniklerimize getirilen 14 adet köpek oluşturdu. Köpekler 7’şerli iki gruba ayrıldı. Birinci
grupta indüksiyon amacıyla ksilazin HCl (1 mg/kg, iv) – ketamin HCl (2.5 mg/kg,
iv) kombinasyonu, ikinci grupta ise propofol (6 mg/kg, iv) kullanıldı. Her iki
grupta da indüksiyonu takiben köpekler entübe edilerek anestezinin devamı
sevofloran ile sürdürüldü. Operasyon öncesinde ve 5, 15, 30, 60. ve 90.
dakikalarında köpeklerin; vücut sıcaklıkları, solunum sayıları, kalp atım
sayıları ve oksijen saturasyonları kaydedildi. Ayrıca kan serumunda glikoz,
AST, ALT, BUN ve kreatinin değerleri belirlendi. Operasyondan sonra 2, 4, 6, 8,
12 ve 24. saatlerde kalp atım sayısı, solunum sayısı ve vücut sıcaklıkları
kaydedildi. Postoperatif aynı saatlerde basit ağrı tanımlama skalası (BAS),
Melbourne ağrı skalası (MAS) ve Glaskow kompozit ağrı skalasına (GKAS) göre
değerlendirme yapılarak gruplar ağrı bakımından karşılaştırıldı. Postoperatif 4.
saatte kalp atım sayıları grup içinde istatistiksel olarak farklı bulunmasına
rağmen gruplar arasında benzerdi. BAS, MAS ve GKAS’na göre I. Grupta postoperatif
6, II. grupta postoperatif 4. saatte istatistiksel olarak anlamlı bir fark
belirlendi. Sonuç olarak ketaminin analjezik etkisinin operasyon sonrası
dönemde propofole kıyasla daha uzun süre devem ettiği görüldü.
Family Medicine Preceptorships for First Year Medical Students: Durable Educational Value Amid Healthcare Transformation
Authors: Boulger James , Onello Emily 
Published: June 2018

In existence for decades, the first year required Family Medicine Preceptorship at the Duluth regional campus of the University of Minnesota Medical School has provided students with opportunities to work with regional family physicians. Exposing medical students to excellent primary care of patients early in the curriculum remains an educational priority. This time series analysis for the years 1992, 2002 and 2012 examines the physician’s practice structure (physician-owner versus employed physician) along with physician willingness to participate. As anticipated, the data demonstrate a transition from independent practice to larger health systems; physicians in large health systems at 22.9% (1992); 28.8% (2002); and 64.3% (2012). In addition, a downward trend in the percentage of physicians agreeing to serve as preceptors is reported (1992 at 83.61%; 2002 at 70.97%; and 2012 at 61.22%). This time series analysis also provides comparative data summarizing student opinion and evaluation of these experiences from the years 1992, 2012 and 2015. Despite changes in practice structure and fewer physicians agreeing to precept, the data demonstrate consistently high ratings by medical students over time.
Tracking Medical Students and Graduates from Hometown to Practice using Geographic Information Systems, 2011-2017
Authors: Kochhar Komal , Fancher Laurie M , Brokaw James J , Wilson Jeffrey S , Nalin Peter M 
Published: June 2018

Background: Indiana University School of Medicine (IUSM) through its statewide system provides medical education and clinical experiences across Indiana for more than 1,450 medical students in nine regions, including Indianapolis and eight regional medical campuses (RMCs). The majority of medical students begin their education distributed among the RMCs, and some students continue clinical experiences at the RMCs for their third and fourth years.
Methods: We used a Geographic Information System (GIS) to visualize and document the contribution of our RMCs in Indiana to the physician workforce pipeline. Using data from the 2011-2017 graduating classes, we created a geospatial database that linked key information from student records and public domain sources (e.g., hometown, campus assignment, PGY1 specialty, and practice) with their corresponding locational information. ArcGIS 10.5 GIS software was used to produce a series of maps to visualize patterns in student outcomes among the RMCs over time.
Results: By using GIS to track medical trainees from hometown to practice, we can provide accurate visualization of extensive geographic data. The maps revealed similarities and differences among the RMCs not fully appreciated until visually mapped, including the specialty choice of students from different campuses and the proportion of graduates practicing in medically underserved areas of the state.
Conclusions: GIS maps and their analyses can identify strengths and distinctions among the RMCs while providing accurate descriptions of the role of geography in the professional development journey of the physician workforce. This ongoing project is a major step toward integrating GIS as a familiar tool in academic administration and health workforce research to assist future decision-making by the school leadership.