bluuebunny/crossref_metadata_2025_split huggingface dataset:
Directional Transport of Photogenerated Electrons to Reduction Sites in Covalent Organic Frameworks by Microenvironment Modulation for CO2 Photoreduction
Authors: Bai Junxian , Zhang Mengke , Si Fangyuan , Li Yan , Liang Guijie , Hou Tingting , Li Yingwei 
Published: December 2024

AbstractAs the transfer of photogenerated electrons to CO2 directly determines its reduction performance, it is important to boost the local photogenerated electron density at the reaction site. Herein, a new strategy is demonstrated to evaluate the local photogenerated electron density at the reaction site by modulating the microenvironment of the reaction site at a molecular level based on 3 rationally designed relatively electron‐deficient (ED) and electron‐rich (ER) type COFs. Expectedly, En‐COF‐TAPB‐TDOEB exhibits high photogenerated electron density at the reduction site due to the presence of an additional electric field, whose polarization direction is consistent with that of the basic unit of COFs. As comparison, photogenerated electrons in Am‐COF‐TAPB‐TFB and Pr‐COF‐TFPB‐TAB mostly distribute in benzene and triphenylene, respectively, due to the delay in exciton dissociation and the presence of an electric field with an inverse direction compared with that of the basic unit of the COFs. Consequently, En‐COF‐TAPB‐TDOEB shows superior CO2 photoreduction efficiency to Am‐COF‐TAPB‐TFB and Pr‐COF‐TFPB‐TAB. Further mechanism investigation demonstrates the influence of the polar microenvironment on the excited state and charge separation pathways of the π‐system in En‐COF‐TAPB‐TDOEB, which convincingly confirms that the ability of directional transport of photogenerated electrons to reduction sites in photocatalysts is directly correlated to their activity in CO2 reduction.
Pyrenetetrasulfonic Acid Tetrasodium Salt‐Modified CoFe Layered Double Hydroxide Enables Stable Alkaline Seawater Oxidation
Authors: Zhang Xixi , Li Zixiao , Cai Zhengwei , Yang Chaoxin , Sun Shengjun , Yue Meng , Zhang Min , Wang Xiaoyan , Wang Hefeng , Li Tong , Zheng Dongdong , Sun Xuping , Tang Bo 
Published: December 2024

AbstractSeawater electrolysis is deemed a green and promising technology for producing hydrogen in coastal areas. Nevertheless, ample chloride ions (Cl–) in seawater can corrode anode, especially at ampere‐level current densities (j), which represents a significant impediment to the seawater‐to‐H2 system. In this study, we present a CoFe layered double hydroxide nanoneedle array modified with 1,3,6,8‐pyrenetetrasulfonic acid tetrasodium salt (PTS) on Ni foam (CoFe LDH@CoFe‐PTS/NF) as a highly efficient electrocatalyst for seawater oxidation. It reveals that PTS with a large negative charge density can effectively repel Cl– and keep active sites working stably during alkaline seawater oxidation. Thus, CoFe LDH@CoFe‐PTS/NF demonstrates excellent OER performance and can achieve j of 500 and 1000 mA cm−2 at low overpotentials (η) of 333 and 364 mV. Moreover, it maintains a stable and continuous electrolysis for 500 h with minimal amounts of active chlorine generation.
Ultra‐Bright Stimuli‐Responsive Photonic Crystals for High‐Performance Anticounterfeiting Coatings
Authors: Tian Ziqiang , Zhu Jinyao , Guo Qilin , Chen Lulu , Guo Jia , Wang Changchun 
Published: December 2024

AbstractPhotonic crystals (PCs) with unique light manipulation capability have attracted widespread attentions. However, weak photonic bandgaps, poor structural color saturation, and tedious preparation process restrict their further development and practical application. Herein, an ultra‐bright stimuli‐responsive PC film with excellent optical performance is prepared by assembly of cadmium sulfide@polyacrylic acid (CdS@PAA) core–shell nanoparticles into PCs through molecule‐mediated shearing‐induced assembly technique (MSAT), this fabrication process is fast and facile, the solid periodic micro/nano‐structures can be formed within 10 s, and a wide selection range of structural color can be obtained. The high refractive index of CdS guarantees high brightness of the PC films. The prerequisite of using MSAT for preparation of large‐sized ultra‐bright PC film is that the CdS@PAA nanoparticles possess appropriate thickness of PAA shell. Compared with conventional PCs, the ultra‐bright PC films present strong photonic bandgaps and high structural color saturation, the relative reflectance is up to 130% compared with a standard aluminum mirror, which is more than four times reflectivity of PS@PAA microspheres. In addition, the PC paint is prepared by mashing the ultra‐bright PC film and blending it with transparent polydimethylsiloxane (PDMS) matrix, the PC coating prepared by alkali treated ultra‐bright PC pigments can achieve good water response ability and anticounterfeiting effect.
Chemo‐ and Enantioselective Intermolecular Allylation of Quinolin‐2‐ones
Authors: Li Zihao , Wang Yumeng , Zhou Yuqiao , Xiong Zongli , Wang Jian , Yao Weijun , Wang Zhen 
Published: December 2024

AbstractAn enantioselective C‐, O‐ and N‐ intermolecular allylic reaction of quinolin‐2(1H)‐ones has been developed. The reaction between 3‐hydroxy quinolone and Boc‐protected MBH adducts with Pd‐catalysis provided a series of 1,4‐dihydroquinoline‐2,3‐diones in 20–95% yield accompanied by 69–96% enantioselectivity. In addition, the O‐allylic alkylation could occur by varying the organo‐catalyst and Boc‐protected MBH adducts from benzaldehyde. Furthermore, the N‐allylation of 3‐O‐protected quinolin‐2‐ones with allylic acetates was also realized (40–92% yield, 78–97% ee).
CuBP Microparticle Clusters (MPCs) as a Stable and Efficient Electrocatalyst for High‐Current‐Density Overall Water Splitting
Authors: Lin Shusen , Mandavkar Rutuja , Habib Md Ahasan , Joni Mehedi Hasan , Dristy Sumiya Akter , Burse Shalmali , Lee Jihoon 
Published: December 2024

AbstractDeveloping stable and cost‐effective electrocatalysts for electrochemical water splitting is essential for advancing sustainable hydrogen production. In this work, CuBP microparticle clusters (MPCs) electrocatalyst is demonstrated on a Ni foam substrate, fabricated by using a one‐pot hydrothermal approach followed by post‐annealing treatment. The optimized CuBP electrode exhibits impressive activities for both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER), showing overpotentials of 49 and 220 mV at 50 mA cm−2 in 1 m KOH, which are comparable to benchmark Pt/C and RuO2 electrodes. The bifunctional CuBP achieves a cell voltage of 1.52 V at 50 mA cm−2, outperforming the Pt/C||RuO2 systems and also demonstrating excellent stability over 120‐h operations. At 2000 mA cm−2, a voltage of 3.12 V is required in CuBP||CuBP configuration whereas the hybrid Pt/C||RuO2 design exhibits a significantly lower cell voltage of 2.25 V at 2000 mA cm−2. The superior catalytic behavior of the CuBP electrode can be attributed to the high active surface area due to the micro‐particle topology, the optimal balance of Cu, B, and P, and the enhanced conductivity achieved through vacuum annealing. Overall, the CuBP electrode is highly efficient and has significant potential to replace traditional RuO₂ electrodes.
Positive sweet corn response with selected climate‐smart agricultural practices
Authors: Thapa Binita , Awal Ripendra , Fares Ali , Veettil Anoop , Elhassan Almoutaz , Rahman Atikur , Melaku Nigus , Woldesenbet Selamawit 
Published: December 2024

AbstractTo sustain agriculture for future generations and reduce the adverse impacts on soil health and the environment, there is a need to adopt sustainable and climate‐smart agricultural practices. A field experiment was conducted to study the effects of organic amendments (chicken and dairy manures and biochar) on the soil physicochemical properties, sweet corn (Zea mays) growth, and yield parameters at Prairie View A&M University, Texas. Two rates of biochar (2.5 and 5 t ha−1) and two types of manure (chicken and dairy) applied at three rates (0, 224, and 448 kg total N ha−1) were used in a factorial design with three replications. Plant height, period for each vegetative growth stage, leaf soil plant analysis development, time to reach 50% tasseling and 50% silking stage, cob length, cob diameter, sugar content, and biomass were measured. The results showed that plant biomass was significantly affected by biochar rate, while plant height, cob length, and cob diameter were significantly affected by manure rates. Sweet corn reached tasseling and silking stages earlier in chicken manure‐treated plots than the dairy manure plots. However, the sugar content was significantly affected by both biochar and manure rates. Furthermore, results revealed a strong positive correlation between plant height and cob length, diameter, and biomass; however, there was a negative correlation with tasseling and silking days. Soil phosphorus, total nitrogen, and potassium had a relatively positive correlation with plant growth parameters. Findings showed that different types and rates of amendments significantly influenced sweet corn growth parameters and soil nutrient status, highlighting the importance of adopting climate‐smart agricultural practices for improved crop yield and soil health.
Cascade Reaction Enables Heterointerfaces‐Enriched Nanoarrays for Ampere‐Level Hydrogen Production
Authors: Du Hongfang , He Song , Li Boxin , Wang Ke , Zhou Zhenkai , Li Junhui , Wang Tingfeng , Du Zhuzhu , Ai Wei , Huang Wei 
Published: December 2024

AbstractDesigning high‐performance electrocatalysts with superior catalytic activity and stability is essential for large‐scale hydrogen production via water electrolysis. Heterostructure nanoarrays are promising candidates, though achieving both high activity and stability simultaneously, especially under high current densities, remains challenging. To this end, we have developed a cascade reaction process that constructs a series of heterostructure nanoarrays with rich heterointerfaces. This process involves treating nickel foam (NF) with molten KSCN and transition metal salts. Initially, NF reacts with KSCN to form Ni9S8 nanoarrays and S2− ions, which are subsequently captured by transition metal ions to form sulfides that are directly integrated onto the nanoarrays, resulting in abundant heterointerfaces. Both experimental and theoretical results indicate that these rich heterointerfaces significantly enhance the interfacial interaction between Ni9S8 and RuS2 within the nanoarrays (termed RH‐Ni9S8/RuS2), markedly improving both the intrinsic activity and stability for the hydrogen evolution reaction (HER). Impressively, the RH‐Ni9S8/RuS2 demonstrates exceptional HER performance, achieving a low overpotential of just 180 mV at 1000 mA cm−2 and maintaining stability for up to 500 h under such high‐current‐density conditions. This innovative approach paves the way for the interfacial design and synthesis of high‐performance catalysts for ampere‐level hydrogen production.
BIMReason: Validating BIM model correctness
Authors: Zech Philipp , Burger Peter , Hammes Sascha , Geisler‐Moroder David , Breu Ruth 
Published: December 2024

AbstractCompliance inspections and building analysis are critical to the success of any construction project. At present, such assessments are primarily conducted manually by experts in the architecture, engineering and construction (AEC) sector resulting in a tedious, labor‐intensive, and generally inefficient undertaking. Yet, with the gradual adoption of Building Information Modeling (BIM), automated building analysis and compliance checking become feasible. The Industry Foundation Classes (IFC) has received a lot of traction in the AEC industry as a vendor‐neutral data model. Its well‐defined semantics can be exploited by reasoning engines that allow for semantic reasoning on building models, the core mechanism required for automated compliance checking and building analysis. In this paper, a general‐purpose model checking framework for IFC building models, as well as an appropriate specification layout are introduced. Model checking via semantic reasoning is realized using various technologies from the Semantic Web. To present and evaluate our implementation, a sample specification is developed and tested on two IFC building models.
Supporting the mainstreamed implementation of life cycle assessment
Authors: Lauschke Muriel , Ebertshäuser Sebastian , Horn Rafael 
Published: December 2024

AbstractWith the expansion of the previously energy efficiency‐focused funding programs to include a simplified life cycle assessment (LCA) for new buildings, Germany‘s authorities aim to get closer to the ambitious climate goals. In this way, authorities aim to achieve a broadly accepted and suitable implementation of LCA in the planning process through the established group of energy auditors. Still the energy auditors’ workflows were not adequately represented during the development of the simplified LCA procedures. Resulting challenges that arise for this group from their new LCA task are in the focus of this work. The main challenge is how to reduce the effort to gather LCA input data. In addition, methodological improvements based on already for energy assessment gathered detailed information, such as that on technical services, are compared against flat‐rate aggregates as applied within the current LCA approach. Finally, the influence of the identified LCA‐input data on the LCA‐results will be summarized.
Boswellia serrata Powder Regimen Provides Significant Protection Against Renal Damage and Blood Imbalances in Diabetic Rats
Authors: Kherouf Amel , Kherouf Marwa , Aouacheri Ouassila , Doghmane Amina , Saka Saad , Adem Şevki 
Published: December 2024

ABSTRACTDiabetic kidney disease affects approximately one‐third of diabetes patients. Hyperglycemia and oxidative stress contribute to this condition. Boswellia serrata gum resin is known for its antioxidant properties and potential in managing diabetic complications, though its nephroprotective effects are not well documented. This research aimed to determine the phytochemical constituents of B. serrata using LC–MS analysis and explore its benefits in enhancing hematological markers and improving STZ‐induced renal dysfunction in rats. Diabetes was induced by a single dose of streptozotocin (60 mg/kg). A total of 40 male albino Wistar rats were divided into four groups: normal control, control with B. serrata (2% w/w), and two diabetic groups. One diabetic group served as a positive control, whereas the other received B. serrata powder (2% w/w). Results showed that the powder reduced blood sugar, decreased renal markers, increased albumin, total protein, and restored hematological parameters. It also enhanced β‐cell function and prevented kidney structural abnormalities. Additionally, B. serrata reduced oxidative stress by lowering malondialdehyde and increasing glutathione, glutathione‐S‐transferase, catalase, and glutathione peroxidase in renal tissues. LC–MS identified 37 phenolic compounds, with apigetrin being the most abundant. These findings suggest that B. serrata holds promise for managing diabetes‐related kidney injury.
The role of red rice in craft beer: A sensory and nutritional evaluation
Authors: Santana Julius Cesar O. , Pereira de Gusmão Rennan , Tejo Cavalcanti Monica , de Luna Freire Kristerson Reinaldo , Moreira de Carvalho Leila , Sousa Galvão Mercia , Madruga Marta Suely , Abrantes da Silva Souza Thaisa , Lisboa Hugo M. , Nascimento Amanda P. S. 
Published: December 2024

AbstractBackground and ObjectivesRed rice is widely cultivated in the semi‐arid regions of Northeastern Brazil and is notable for its rich phenolic content and nutritional value. The use of red rice as a nonconventional adjunct in brewing can enhance the sensory and nutritional qualities of craft beers, offering a unique product profile that appeals to the growing demand for differentiated and artisanal beverages. This study aimed to evaluate the sensory and nutritional impact of incorporating red rice from two distinct regions, Bahia and Paraíba, into the brewing process.FindingsThe study analyzed the effects of red rice from Bahia and Paraíba on the antioxidant capacity, phenolic content, and volatile composition of the resulting beers. Beers produced with Paraíba red rice exhibited a higher phenolic content and antioxidant capacity, while the Bahia variety contributed to a more complex aromatic profile. Sensory evaluations showed that the Bahia rice beer received higher ratings for aroma and overall acceptance, whereas the Paraíba rice beer stood out in antioxidant properties.ConclusionsThe inclusion of red rice as a brewing adjunct in craft beer formulations enhances both antioxidant capacity and sensory complexity, contributing positively to consumer acceptance. Utilizing regionally sourced red rice varieties adds distinct sensory attributes to the beers, increasing their appeal within the specialty beverage market.Significance and NoveltyThis research demonstrates the potential of red rice as an innovative and sustainable adjunct for the craft beer industry, offering a nutritionally enriched and sensory‐diverse product. The findings underscore the value of integrating locally grown ingredients to create high‐quality, artisanal beverages that support regional agriculture and promote sensory diversity in the beverage industry.
Secukinumab (Anti‐IL‐17A Therapeutic Antibody) Improves Clinical Outcome for a Mixed Endotype CRS
Authors: Plaas Mihkel , Brazovskaja Agnieska , Kisand Kai , Tserel Liina , Peterson Pärt 
Published: December 2024

ABSTRACTWe identified two CRSwNP patients who had previously failed treatment with an anti‐IL‐4/IL‐13 antibody (dupilumab). Based on their clinical characteristics and blood cytokine levels, we considered them mixed Type II/Type III cases and treated them with an anti‐IL‐17 antibody (secukinumab). Anti‐IL‐17 antibody secukinumab was superior in reducing their NPS and SNOT‐22 values compared to dupilumab. IL‐17 could be a promising target for non‐type II and mixed endotype CRS treatment.
Anaerobic Catalyst Design for Alcohol Oxidation: Fine‐Tuning Copper/TEMPO with Bipyridine Proportions
Authors: Rodrigues Matheus G. B. , de Melo André L. Pesquero , Coutinho‐Neto Maurício D. , Angelucci Camilo A. 
Published: December 2024

AbstractIn this study, we investigate the indirect electro‐oxidation of benzyl alcohol (BA) using the copper/TEMPO catalytic system, which combines copper complexes with 2,2,6,6‐tetramethylpiperidin‐1‐oxyl (TEMPO) in an anaerobic medium. We reexamine the impact of bpy ligand proportions, exploring ratios of 1:1, 2:1, 3:1, and 4:1 on catalytic activity. Cyclic voltammetry and visible spectroscopy reveal distinct electrochemical characteristics and complex formations at different bpy ratios. Simulations uncover intricate energy equilibria involving ion coordination, varying with oxidation state, and bpy proportion. Theoretical and experimental spectra align, supporting the proposed structures. The Brønsted base, triethylamine (TEA), essential in this anaerobic system, shows different voltammetric profiles with each ligand ratio, revealing key interactions with bpy complexes. In the presence of BA, the 1:1 and 2:1 ratios exhibit indirect catalytic activity, with the 2:1 ratio yielding significantly higher current densities. This establishes a new optimal condition where formed in a 2:1 stoichiometry demonstrates superior activity with a lower redox potential, while maintaining labile coordination points for necessary interactions. Theoretical results also indicate weaker TEMPO coordination to .
Analysis of Cochrane systematic reviews: A comprehensive study of impact and influence from 1998 to 2024
Authors: Sharifan Amin 
Published: December 2024

AbstractIntroductionEvidence from Cochrane systematic reviews has significantly impacted clinical practices across diverse disciplines and is widely integrated into international guidelines. To date, there are no bibliometric analyses of Cochrane's publications.MethodsThe search encompassed the Scopus database from inception to May 2024, with results limited to studies published by the Cochrane Database of Systematic Reviews. The analysis examined annual trends and publication volumes, citation patterns, contributing countries, authors, institutions, funding sources, and common keywords. Scopus' built‐in analytical tools, the bibliometrix package in RStudio, and VOSviewer software facilitated the analysis of the results.ResultsA total of 12,150 systematic reviews were eligible. There was a fluctuating pattern in publication and citation trends within Cochrane reviews, with a decline in both metrics since 2016. Contributions mainly came from high‐income countries, their institutions, and authors residing there, with significant government funding supporting publications in these regions. The United Kingdom (27%), Australia (10%), and the United States (9%) had the greatest contributions among other countries, respectively. Furthermore, the demographic emphasis in Cochrane reviews was concerned with female and male participants as well as children and adult populations, hinting at the potential underrepresentation of minor gender identities and older adults in the synthesis of evidence.ConclusionCochrane should actively involve researchers and experts from low‐ and middle‐income countries in evidence synthesis, ensure underrepresented and low‐resource regions are included in its emerging Evidence Synthesis Units and Thematic Groups, and prioritize the inclusion of geriatric populations and sexual and gender minorities in its evidence to enhance inclusivity and global representation.
Current Approaches and Strategies Applied in First‐in‐class Drug Discovery
Authors: Mohammed Idrees , Sagurthi Someswar Rao 
Published: December 2024

AbstractFirst‐in‐class drug discovery (FICDD) offers novel therapies, new biological targets and mechanisms of action (MOAs) toward targeting various diseases and provides opportunities to understand unexplored biology and to target unmet diseases. Current screening approaches followed in FICDD for discovery of hit and lead molecules can be broadly categorized and discussed under phenotypic drug discovery (PDD) and target‐based drug discovery (TBDD). Each category has been further classified and described with suitable examples from the literature outlining the current trends in screening approaches applied in small molecule drug discovery (SMDD). Similarly, recent applications of functional genomics, structural biology, artificial intelligence (AI), machine learning (ML), and other such advanced approaches in FICDD have also been highlighted in the article. Further, some of the current medicinal chemistry strategies applied during discovery of hits and optimization studies such as hit‐to‐lead (HTL) and lead optimization (LO) have been simultaneously overviewed in this article.