bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuroimaging signs of brain lesions in patients with gene-associated microangiopathy (CADASIL)
Authors: Kurochkina N. S. , Moroz A. A. , Konovalov R. N. , Abramycheva N. Yu. , Krotenkova М. V. , Illarioshkin S. N. 
Published: February 2019

Purpose. To evaluate specific changes in MRI of the human brain, associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).Materials and methods. We enrolled 24 patients with genetically confirmed CADASIL (19–81 y.o.). The following MRI sequences were performed for every subject: T1 MPR, T2, T2-FLAIR, DTI and SWI. Brain tissue lesions were assessed using STandards for ReportIng Vascular changes on nEuroimaging (STRIVE).Results. In the CADASIL group the following changes were observed (in % of patients): recent small subcortical infarcts – none; lacunes – 54%; white matter hyperintensities (WMH) by Fazekas 1 – 12%, Fazekas 2 – 17%, Fazekas 3 – 71% (sites of predilection: anterior temporal lobe and external capsule); cerebral microbleeds – 42%; enlarged perivascular spaces – 88%; brain atrophy – 27%.Conclusion. Neuroimaging signs of brain lesions are common for all types of cerebral small vessel disease, including CADASIL. However, there are some features in patients with CADASIL. The detection of petechial intraparenchymal hemorrhages is a diagnostically and prognostically useful marker, so it is very important to use gradient echo planar T2* or SWI sequence in the conventional MRI protocol.
Pitfalls in pancreatic lesion diagnostics: an accessory intrapancreatic spleen
Authors: Tyunibabyan A. I. , Blokhin I. A. , Chernina V. Yu. , Kaldarov A. R. , Karmazanovsky G. G. 
Published: February 2019

Introduction. Accessory spleen (splenunculus) is one of the most common benign congenital anomalies in humans. The location of splenunculus may vary from perisplenic, greater omental or mesenterial to intraparenchymal (pancreas, stomach, duodenum, etc.). In the latter case, the additional spleen is called ectopic (from the greekektoposdisplaced). Most frequently detection of such splenic lobules occurs accidentally via abdominal ultrasound.Objective: two cases of verified intrapancreatic accessory spleen (IPAS) and main criteria for differential diagnosis with other hypervascular pancreatic lesions.Materials and methods. We present two case reports: a 43-year-old woman with a history of kidney cancer and a healthy 61-year-old man. In both cases, pancreatic neuroendocrine neoplasia (NEN) was initially suspected. Preoperative diagnostics included abdominal ultrasound examination and multiphase dynamic computed tomography (CT) with intravenous bolus nonionic iodine-based contrast agent (native, arterial – 10 sec, venous – 60 sec and delayed – 300 sec after threshold density of 150 HU in the aorta was exceeded). In one case magnetic resonance imaging (MRI) including axial, sagittal and coronal T1and T2-weighted images, diffusion-weighted images and dynamiccontrast-enhanced series with gadolinium chelate was performed. Both patients underwent robotic assisted distal pancreas resection. Morphological examination revealed IPAS.Results. In contrast-enhanced computed tomography IPAS has densitometric parameters similar to the spleen. Generally, magnetic resonance imaging does not differentiate IPAS, NEN and hypervascular metastases, since all three are generally T2-hyperintense and T1-hypointense. Contrast enhancement pattern with gadolinium chelateswas similar to CT-contrast enhancement pattern.Conclusion. Intrapancreatic accessory spleen does not require surgical treatment. Therefore, differential diagnosis between IPAS and neuroendocrine neoplasia, solid pseudopapillary tumor and hypervascular pancreatic metastases is crucial. MRI has an advantage with non-invasive diffusionweighted images (DWI). The apparent diffusion coefficient (ADC) of IPAS will be quantitatively similar to the main spleen while other lesion will demonstrate lower ADC values. Scintigraphy with red blood cells bound with 99mTc utilizes the reticuloendothelial system (RES) in the spleen demonstrating characteristic uptake in the IPASand the main spleen. Ultrasound with color Doppler and contrast enhancement may be a good addition to our armamentarium. One can evaluate the vascular pedicle of the IPAS, as well as contrast agent retention in RES via sonography. We believe the multimodal approach including MRI with DWI/ADC to be the most effective.
COMPLEX RADIALOGICAL DIAGNOSTICS IN DRUG-DEPENDENT PATIENTS WITH PHOSPHORUS OSTEONECROSIS OF THE FACIAL SKELETON AT THE PREOPERATIVE STAGE
Authors: Babkova A. A. , Serova N. S. , Medvedev Yu. A. , Pasha S. P. 
Published: February 2019

The purpose.To determine the role of complex radiological diagnostics and diagnostic effectiveness of various radiological methods in drug-dependent patients with phosphorous osteonecrosis of the facial skeleton at the preoperative stage.Materials and methods.The study included 85 drug addicted patients with a diagnosis of toxic phosphorus osteonecrosis of the facial skeleton. In the preoperative period all patients underwent full clinical and radiological examination. Orthopantomography (OPG), skull x-ray, multislice computed tomography (MSCT), cone-beam computed tomography (CBCT) were performed in 85 patients (100%) at the preoperative stage. Also, 19 patients (22.4 %) underwent radionuclide diagnostics, which included planar scintigraphy and single-photon emission computed tomography (SPECT). Further, all patients underwent surgical treatment to the extent of complete or partial resection of the jaws and other bones of the facial skeleton.Results.According to the data of complex radiological examination at the preoperative stage it was revealed that in 48% (n = 41) cases the osteonecrosis zones were localized in the lower jaw, in 24% (n = 20) in the upper jaw, in 28% (24) patients the pathological process captured both jaws. Also, MSCT and CBCT data revealed the spread of the pathological process to other bones of the facial, in some cases, the brain part of the scull in 25 patients (29.5%). The data of radionuclide diagnostics allowed to reveal the zones of radiopharmaceutical accumulation both in the bones of the skull and outside it. Based on the results of the analysis of the data obtained, the role of complex radiation diagnosis was determined, as well as the diagnostic effectiveness of radiation methods (OPG, X-ray of the skull, MSCT, CBCT) in the examination of drug-dependent patients with phosphoric osteonecrosis of the facial skeleton at the preoperative stage.Conclusion.The complex radiological diagnostics with application of high informative modern methods (MSCT, CBCT, radionuclide diagnostics) is the required step in the evaluation of patients with osteonecrosis of the facial skeleton at the preoperative stage. The diagnostic efficiency parameters for MSCT were: sensitivity – 98.1%, specificity – 99.6%, the accuracy – 98.8%, for CBCT: sensitivity – 97.3%, specificity – 99.1%, accuracy – 98.4%, for OPG: sensitivity – 78.6%, specificity – 76.3%, accuracy – 77.4%, for radiography of the skull: sensitivity – 61.1%, specificity – 59.2%, accuracy – 60.2%.
Comparative analysis of TI-RADS modifications
Authors: Sich Yu. P. , Fisenko E. P. 
Published: February 2019

There is no single classification of TI-RADS. In different countries, various modifications are used. It is necessary to compare different versions of the classification for choosing the most optimal variant.Objective: a comparative “blind” assessment of the thyroid nodules identified by ultrasound, according to the TI-RADS scale in various modifications.Materials and methods. Retrospective analysis of 153 echograms of thyroid lesions: colloid goiter/nodular colloid goiter – 77 observations, autoimmune thyroiditis – 11, follicular adenoma – 77, follicular cancer – 2, medullar cancer – 1, papillary cancer – 36 observations.Results.A comparative evaluation of the reproducibility of the three modifications of TI-RADS was carried out – the opinions of independent experts were homogeneous. Ultrasonic criteria for the evaluation of thyroid nodules for each TI-RADS variant are presented. The European and proposed by Russian authors variants, in addition to the large signs of malignancy, use small features extended in the domestic version of TI-RADS, which increases the sensitivity of these classification options.Тhe shortest time to evaluate thyroid formations was required when using the European classification. The European and proposed by Russian authors variants, in addition to the large signs of malignancy, use small signs, which increases the sensitivity of these classification options until 51 and 53%. The higher sensitivity of the korean variant – 57.8%.Conclusions. It is necessary to further discuss the TI-RADS options and find the most optimal solution.
The role and possibilities of automated breast ultrasound in breast cancer screening in women with high density breast tissue
Authors: Solodky V. A. , Meskich E. V. , Erstein M. A. , Kolesnik A. Yu. , Oksanchuk E. A. , Nudnov N. V. 
Published: February 2019

The aim of our study was to improve the diagnosis of breast nodules on a high dense breast tissue. The study involved 280 women with high dense breast tissue (ACR C,D BI-RADS 2015) aged 26 to 83 years (mean age 47.5 years), all women underwent standard digital mammography in two projections and automated breast ultrasound scanning in three projections. The addition of ABUS to mammography in the basic algorithm of the study increases the effectiveness of the diagnosis of nodules: increased sensitivity by 22.9% (MG – 75.9%, MG+ABUS – 98.8%), reduced specificity by 6.95% (MG – 86.7%, MG+ABUS – 79.75%), the added value is 11.25%. The added value of ABUS and HHUS are equal, but the ABUS allows to standardize, store and transmit the data with the possibility of a second reading, as well as to reduce the time of interpretation of the study twice in comparison with HHUS. Thus, ABUS can be used as an additional screening method for women with high dense breast or as the main method of mass examination for young women.
Breast density as a risk factor of development of ductal carcinoma in situ
Authors: Puchkova O. S. , Sinitsyn V. E. , Bogomazova S. Yu. , Mershina E. A. , Shirokiy V. P. , Bazhenova D. A. , Nenaydenko E. V. 
Published: February 2019

Objectives. to reveal a potential relationship between the breast density, various radiographic patterns of the breast structure, and the risk of developing ductal adenocarcinoma in situ.Methods.In this study, 169 patients were divided into 2 groups according to the modern X-ray classification L. Tabar. All patients underwent a core biopsy with subsequent histological examination. The first group consisted of 57 women (33.7%) with tumors arising in the terminal ductal-lobular unit – acinar adenocarcinoma (AAB) unifocal and multifocal forms, and the second group – 112 women (66.3%) with types of ductal adenocarcinoma in situ (in situ DAB) and ductal adenocarcinoma in situ associated with the acinar form of breast cancer (DAB + AAB). Pathologic findings on mammography were assessed using the modern classification of L. Tabar. Evaluation of the breast density was made using ACR 2013 classification. The Pattern of radiologic breast structure was evaluated according to the classification of L. Tabar.Results. According to our results, statistically significant differences of the compared groups on the breast density were established (p < 0.001). In the first group, patients with a density of ACR 1 prevailed, the proportion of which was 52.6%. In the second group, the incidence of ACR 4 was highest, with a share of 32.1% among all patients. Thus, it was concluded that there is an association of the breast density ACR 3 and ACR 4 and risk of development of DAB.Conclusions. The high breast density, as well as the IV and V type of the breast structure according to L. Tabar's classification, are statistically associated with an increased risk of developing ductal carcinoma in situ (DAB). Our study also showed a statistically significant difference in the age of onset of ductal and acinar adenocarcinoma of the breast – 52 and 64, respectively.
Coexistence xanthogranulomatous pyelonephritis with renal replacement lipomatosis. Computed tomography. Сlinical case
Authors: Abovich Yu. A. , Afukova O. A. , Yudin A. L. 
Published: February 2019

Xanthogranulomatous pyelonephritis is a relatively rare form of chronic pyelonephritis. It is characterized by combination of destructive and proliferative processes with proliferation in the kidney of granulomatous tissue with a large number of lipid-containing macrophages, which are called xanthomous or "foamy" cells. Replacement kidney lipomatosis is also a rare disease that is characterized by proliferation of adipose tissue of the kidney sinus and perirenal adipose tissue with pronounced atrophy of the renal parenchyma. This is the result of renal atrophy, chronic inflammation, nephrolithiasis or long-term current hydronephrosis with the proliferation of adipose tissue in the renal sinus and paranephric fiber. The article presents a case of combining the above-mentioned pathological processes in a patient of the 93-ies. According to clinical manifestations and examination data, xanthogranulomatous pyelonephritis can occur under the guise of pionephrosis, carbuncle, abscess. Deservedly this disease is called "great imitator", because today there are no clear diagnostic criteria, and the diagnosis is established, as a rule, in the postoperative period.
Renal arteriovenous malformations: diagnosis and treatment
Authors: Askerova A. N. , Stepanova Yu. A. , Zotikov A. E. , Ivandaev A. S. , Karmazanovsky G. G. 
Published: February 2019

Renal arteriovenous fistula is a comparatively rare malformation that accounts for < 1% of all arteriovenous fistulas malformations. Renal ANM are devided into congenital or acquired, traumatic and nontraumatic, that can cause massive hematuria, pain, retroperitoneal hemorrhage, and heart failure. Non-invasive imaging modalities, including US, MDCT and MRI, are widely used to diagnose this payhology, but the gold standard for the diagnosis of renal AVM remains angiography. The advantage of angiography in comparison with other methods is the possibility of simultaneous treatment of such patients. The treatment of renal AVM can include endovascular dissociation of the arteriovenous fistula or an open operation, including the using of ex vivo techniques. The choice of method of the treatment is based on the general patient status and the characteristics of renal arteriovenous malformation.
X-ray contrast media: focus on safety
Authors: Khokhlov A. L. , Kabanov A. V. , Kozlova O. G. 
Published: February 2019

The article presents a modern classification of contrast media, the advantages and disadvantages of radiographic contrast media. The most important adverse events ofcontrast media such as hypersensitivity reactions, thyroid dysfunction andcontrast-induced nephropathy are discussed.
SIFAT KIMIA TANAH DAN POPULASI KUMBANG TANDUK (Oryctes rhinoceros L.) STADIA PRADEWASA PADA BERBAGAI KEDALAMAN PENEMPATAN TANDAN KOSONG KELAPA SAWIT
Authors: Fauzana Hafiz , Alfasiri Ayubi , Nelvia Nelvia 
Published: February 2019

Oil palm is a very significant industrial plant in producing vegetable oils that require high levels of nutrients in its cultivation. Cultivation of oil palm yield can produce industrial waste, the oil palm empty trunks (TKKS) which have the potential to supply nutrients to oil palm land. The placement of empty trunks at various depths is expected can give effect to the population of Oryctes rhinoceros L pre-adult stage and chemical soil properties. This research was conducted on oil palm plantation in PT. Perkebunan Nusantara V Sei Galuh Tapung, Kampar, Riau from July to October 2017. The aim of this research is to examine the effect of empty trunks placement against the Oryctes rhinoceros L population development and chemical soil properties. This research was done using a randomized experiment design complete with the treatment of the depth empty trunks placement (placement of oil palm empty trunks on the ground at the depth of 10 cm, 20 cm, and 30 cm) which is repeated four times. The observed parameters include the population of infestation of Oryctes rhinoceros L (population of eggs, larvae and pupae) and soil chemical properties (soil pH, C-organic, N-total, P-total and K-total). The results showed that empty trunks placed below the surface at various depths affected the Oryctes rhinoceros L population. Placement of TKKS depth in the soil cannot be infested by Oryctes rhinoceros L. Placement of empty trunks at the depth of the soil tends to increase pH (from very acidic categories to acidic categories) and total K (from the low category to very high category), is not effected on C-organic and N-total and can reduce P-total (from the very high category to the high category) if compared to the placement of empty trunks on the ground.Key words : Chemical Soil properties, Oryctes rhinoceros L., Oil palm Empty trunks, Soil depth
HUBUNGAN AKTIVITAS IBU HAMIL DENGAN KEJADIAN PERSALINAN PREMATUR
Authors: Murtiningsih Murtiningsih 
Published: February 2019

Prematuritas masih merupakan penyebab terbanyak kedua kematian bayi usia 0-6 hari dengan persentase 34%. Faktor resiko yang berkontribusi terhadap persalinan prematur diantaranya faktor resiko modifiable. Faktor tersebut yaitu aktivitas fisik. Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik ibu pada saat kehamilan dengan kejadian persalinan prematur. Desain penelitian korelatif dengan pendekatan cross sectional. Sebanyak 27 orang ibu dengan persalinan prematur menjadi responden dengan tehnik accidental sampling. Alat pengumpulan data berupa pedoman wawancara. Hasil analisis univariat didapatkan karakteristik responden pada usia resiko tinggi 48.1%, pendidikan rendah 66.7%, riwayat premature 18.5%, kebiasaan merokok 40.7%, pre eklamsia 40.7%, BMI pra-konsepsi tidak normal 40.7%. Aktivitas ibu hamil berat 33.3% dan yang mengalami persalinan prematur berat (<34 mg) 59.3%. Hasil analisis bivariat terdapat hubungan signifikan antara aktivitas fisik ibu pada saat kehamilan dengan kejadian persalinan prematur (p=0,033). Ibu hamil yang beraktivitas berat yaitu berdiri lebih dari 2 jam/hari mempunyai resiko 10 kali lebih tinggi mengalami persalinan prematur berat. Hasil penelitian ini dapat menjadi acuan bagi tenaga kesehatan perlunya meningkatkan pengetahuan tentang faktor yang berkontribusi terhadap kejadian persalinan prematur, yaitu aktivitas selama kehamilan. Tenaga kesehatan dapat memberikan pendidikan kesehatan atau konseling sedini agar ibu hamil melakukan aktivitas ringan selama kehamilannya sehingga persalinan prematur dapat dicegah. Hal ini berkontribusi terhadap penurunan morbiditas dan mortalitas akibat persalinan prematur. Perlu dilakukan penelitian lanjutan dengan cohort atau desain quasi eksperimen tentang pembatasan aktivitas ibu hamil untuk mencegah persalinan prematur.
Realistic Texturing pada Objek 3-dimensi Menggunakan Model Tehnik Texture Mapping
Authors: Ula Mutammimul 
Published: February 2019

Abstrak Tekstur merupakan karakteristik penting dari penampilan objek dalam pemandangan alam, dan merupakan syarat kuat dalam persepsi visual. Pemahaman tekstur merupakan bagian penting dari memahami visi manusia. Pada objek 3-dimensi pemberian tekstur merupakan hal yang harus dilakukan agar objek terlihat lebih realistis. Maps berwujud gambar tekstur 2D dituangkan ke permukaan geometri/objek untuk membuat penampilan objek tersebut tampak halus untuk detail permukaannya. Pada pengembangan grafik realisme tingkat tinggi diperlukan lebih banyak lapisan tekstur, agar hasil mapping mendekati kesempurnaan. Sebuah tekstur maps yang diterapkan (dipetakan) biasanya dipakai untuk permukaan bentuk objek polygon, proses ini mirip dengan menerapkan texture pada kertas berpola kotak putih yang polo. Pada penelitian ini proses pemberian teksture pada objek 3-dimensi meliputi lantai, furniture dan gedung. Tekture yang digunakan didapat dari mengambil dari photo objek tersebut dalam dunia nyata.Kata Kunci: texturing, texture mapping,3-dimens,
Alimentación y pobreza por carencia de acceso a los alimentos en población del noreste de México
Authors: Ramos Peña Esteban Gilberto , Salas García Rogelio , Nuñez Rocha Georgina Mayela , Ramírez López Erik 
Published: February 2019

RESUMENIntroducción: La alimentación es el factor primordial que afecta a la salud, la calidad del patrón de consumo de alimentos puede ser modificada por la pobreza por acceso a los alimentos. Objetivo: Estimar si la calidad de la alimentación está asociada a la pobreza por acceso a los alimentos en población del noreste de México. Material y métodos: Se analizó la base de datos de la Encuesta Estatal de Salud y Nutrición Nuevo León 2011/2012 que contiene una muestra probabilística de 7,290 individuos. La variable calidad del patrón de consumo alimentario se construyó a partir de la Encuesta Estatal de Salud y Nutrición Nuevo León 2011/2012 y la variable pobreza por acceso a los alimentos a partir de registros nacionales. Se utilizaron pruebas estadísticas no paramétricas. Resultados: El mayor porcentaje de la población analizada se encuentra en la categoría de necesidad de cambio en la calidad del patrón de consumo alimentario, el cuartil con menor pobreza tiene mayor porcentaje de calidad adecuada del patrón de consumo alimentario que el cuartil de mayor pobreza, lo contrario sucede en cuanto a la calidad inadecuada. Conclusiones: La calidad del patrón de consumo en general y por grupos de alimentos está asociada a la pobreza de acceso a los alimentos. ABSTRACTIntroduction: Food is the primary factor that affects health, the quality of the pattern of food consumption can be modified by poverty due to access to food. Objective: To estimate whether the quality of food is associated with poverty due to access to food in the population of northeastern Mexico. Material and methods: The database of the Nuevo León State Health and Nutrition Survey 2011/2012 was analyzed, which contains a probabilistic sample of 7,290 individuals. The quality variable of the food consumption pattern was constructed from the State Survey of Health and Nutrition Nuevo Leon 2011/2012 and the variable poverty for access to food from national registers. Nonparametric statistical tests were used. Results: The highest percentage of the analyzed population is in the category of need for change in the quality of the pattern of food consumption, the lowest-poverty quartile has a higher percentage of adequate quality of the food consumption pattern than the highest-poverty quartile, the opposite happens in terms of inadequate quality. Conclusions: The quality of the consumption pattern in general and by food groups is associated with poor access to food. Palabras clave: Food, Poverty, Mexico
¡Coja Oficio!, el devenir de los oficios que se extinguen y la necesidad que no da tregua. Fotoreportaje
Authors: Cardona Cadena Ella Carolina , Cárdenas Moreno Laura Consuelo 
Published: February 2019

Esta reflexión es recogida en la cámara de -Laura Consuelo Cárdenas Moreno, Estudiante de Artes Audiovisuales UNAB, quien dirige un trabajo documental en el que expone el sentir de algunos personajes que han vivido la experiencia de ver desaparecer su modus vivendi.
El proyecto documental transmedia puede ser consultado en la página web http://www.sinoficio.com.co/