bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the Impact of Airport Relocation on the Transport Network in Special Region of Yogyakarta, Indonesia
Authors: Fitrada Andrean Gita 
Published: May 2019

Adi Sutjipto International Airport is the airport currently operated in Special Region of Yogyakarta (SRY), located near the city centre area. SRY needs to construct a new airport due to the increase in air passengers. The proposed airport, named New Yogyakarta International Airport (NYIA) is located in the undeveloped area, away from the city centre. This study is aimed to investigate the impact of airport relocation to the road network and to assess several developments of transportation infrastructures to the new airport. The analysis was conducted by developing a transport network model using PTV Visum. The secondary data collected from the local government to develop the transport network model, including the development of origin-destination matrices and forecasting purpose. The scenarios of road infrastructures development and new rail service to the airport in 2025 are then modelled. The results showed that the road infrastructure developed can reduce the number of congested main roads from 9.47% into 5.94%. Rail service to the airport is effective to decrease the traffic congestion at two NYIA roads access and able to increase their average speed from 49.45 and 44.29 km/h into 66.45 and 62.66 km/h.
The Effects of Water to Solid Ratio, Activator to Binder Ratio, and Lime Proportion on the Compressive Strength of Ambient-Cured Geopolymer Concrete
Authors: Adam Andi Arham 
Published: May 2019

Low calcium fly ash based Geopolymer has been proven to be one of the potential alternatives substitutes to Portland Cement not only due to its high resistance to chemical attack but also because of the vast availability of class F fly ash for raw materials. However, one of the limitations of geopolymer as the alternative binders in concrete is that the strength develops slowly under ambient condition. This paper presented the investigation of water to solid ratio, activator to binder ratio, and lime proportion on the compressive strength of ambient-cured geopolymer concrete. To develop sufficient strength at an early age, class F fly ash and slaked lime (Ca (OH)2) were used as the binder with the proportion of lime to binder of 4%, 5%, 6%, and 7%. The blended binder was activated by sodium silicate and sodium hydroxide solution with the variation of activator to binder ratio of 0.45, 0.5, 0.55, and 0.6. The water to solid ratio of 0.30, 0.31, 0.32, and 0.33 was chosen to facilitate good workability which was done by adding water to the mix. The compressive strength tests were conducted at 7, 14, and 28 days on the cylindrical concrete specimens with a dimension of 100 mm diameter and 200 mm height. The results show that the activator to binder ratio of 0.50 to 0.55, and the proportion of lime to the binder of 6% to 7% were the optimum range value. It was also found that the lower the water to cement ratio the higher the compressive strength and the water to solid ratio as low as 0.3 produced the highest compressive strength while still maintaining good workability.
Medicina Alternativa y Complementaria: ¿Qué experiencias tienen las personas al utilizarla?
Authors: Velasco Lozano Edwin Alexis , Gusman Morales Eduardo , Ordoñez Monroy Ana Lorena , Torres Razo Daniel , De la Garza Castañón Nohemí , Álvarez Martínez Christopher , Guillén Cadena Dulce María 
Published: May 2019

<p class="p1"><strong><em>Introducción: </em></strong><em>El incremento del uso de la Medicina Alternativa y Complementaria (MAC) se puede sustentar en la eficacia reportada y escasos efectos secundarios. Sin embargo, no hay suficientes investigaciones sobre posibles complicaciones e interacciones con los medicamentos convencionales. </em><strong><em>Objetivo: </em></strong><em>Describir las experiencias de mujeres que hayan utilizado la medicina alternativa y complementaria </em><strong><em>Metodología: </em></strong><em>Investigación cualitativa con diseño fenomenológico descriptivo. La recolección de datos se realizó a través de entrevistas a profundidad, con una guía que incluyó los temas relacionados con el fenómeno a investigar, observación y notas. El análisis se realizó según lo propuesto por Krueger: lectura, transcripción, codificación, formación de temas y sub temas, se aplicaron los criterios de rigor y el consentimiento informado. </em><strong><em>Hallazgos: </em></strong><em>Se encontró que los principales motivos por los cuales las entrevistadas acudieron a la medicina alternativa fueron por recomendación de familiares o conocidos así como la asequibilidad de la misma. Las entrevistadas admiten utilizar 1 o más métodos alternativos, de los cuales sobresale la herbolaria, para tratar patologías específicas y/o síntomas generales. Sobre sus emociones y sentimientos que les causó el uso de la MAC sobresalen la confianza y bienestar que les genera. También se identificó una creencia sobre la inocuidad de los remedios herbolarios ya que creen que son inofensivos. </em><strong><em>Conclusiones: </em></strong><em>La experiencia de las participantes con la MAC fue en lo general positiva y ninguna reportó efectos secundarios por el uso de la misma. Por esta sensación de bienestar percibida, las personas tienen una gran confianza en sus efectos sanadores.<span class="Apple-converted-space"> </span></em></p>
Korelasi kepadatan nyamuk Anopheles spp. terhadap faktor-faktor meteorologi di Desa Sungai Nyamuk, Kabupaten Nunukan, Kalimantan Utara
Authors: Sugiarto Sugiarto , Hadi Upik Kesumawati , Soviana Susi , Hakim Lukman 
Published: May 2019

Korelasi antara angka menggigit Anopheles (man biting rate-MBR) dengan faktor-faktor meteorologi sangat penting untuk mengantisipasi fluktuasi kejadian malaria. Penelitian ini bertujuan untuk menganalisis korelasi kepadatan Anopheles spp. dengan faktor-faktor meteorologi di Desa Sungai Nyamuk, daerah endemis malaria di Kalimantan Utara. Kepadatan nyamuk Anopheles spp. didapatkan dari umpan orang (human landing collection-HLC) (pengamatan 18.00-06.00). Pearson Product Moment Test digunakan untuk menganalisis korelasi antara angka menggigit Anopheles (MBR) dengan faktor-faktor meteorologi. Hasil penelitian menunjukkan bahwa curah hujan mempunyai hubungan bermakna dengan kepadatan Anopheles (MBR), sedangkan kepadatan Anopheles mempunyai hubungan bermakna dengan kejadian malaria. Suhu udara dan kelembaban tidak mempunyai hubungan bermakna dengan kepadatan Anopheles (MBR). Curah hujan dapat dijadikan sebagai salah satu indikator dalam penerapan sistem kewaspadaan dini untuk mengantisipasi fluktuasi kejadian kasus malaria.
Prediction of severity of hemorrhagic fever with renal syndrome
Authors: Lyubushkina A. V. , Popova L. L. , Nedugov G. V. , Konstantinov D. Yu. , Stulova M. V. 
Published: May 2019

The aim is to develop a method of early prediction of the severity of hemorrhagic fever with renal syndrome on the basis of clinical and laboratory data.A comprehensive clinical and laboratory examination of 144 patients with hemorrhagic fever with renal syndrome was carried out in the period of 2–5 days from the onset of the disease. Based on the discriminant analysis of the data obtained, a discriminant model for predicting the severity of hemorrhagic fever with renal syndrome was developed. The index of accuracy of prognosis of clinical forms of the disease on the basis of the developed discriminant model is 97.4%.
Identification of Bordetella holmesii among the patients hospitalized with suspicion of pertussis and pertussis-like illnesses
Authors: Gadua N. T. , Borisova A. B. , Pimenova A. S. , Borisova O. Yu. , Petrova M. S. , Shamsheva O. V. , Afanas’ev S. S. , Kafarskaya L. I. , Vlasov E. V. , Afanas’ev M. S. , Aleshkin A. V. , Bunin S. V. , Aleshkin V. A. 
Published: May 2019

Purpose.To reveal and estimate prevalence of B. holmesii among the patients hospitalized with suspicion pertussis and pertussis-like illnesses.Materials and methods. 424 clinical samples received from patients with of pertussis and pertussis-like illnesses in GBUZ IKB № 1 DZM in 2017–2018 are investigated. Identification of fragments of a genome of Bordetella was carried out in PCR-RT with “Amplisens® Bordetella multi-FL”. For identification of fragments of a genome of B. holmesii used PCR-RT with primers of IS481, IS1001 and hIS1001.Results.The research included 424 patients, from them 56,1% of children aged till 1 year, 41,3% of children – are more senior than 1 year and 2,6% of adults. When using test system 60,4% of the samples containing DNA of B. pertussis are revealed; 1,9% of samples – DNA of B. parapertussis; in 34,9% of samples it is received negative and in 2,8% – doubtful results. The research of 424 samples in PCR-RT by means of IS481, IS1001 and hIS1001 primers showed that 61,1% of samples contained DNA of B. pertussis; 0,7% of samples – DNA of B. parapertussis and 3,8% of samples – DNA of B. holmesii. In 143 samples the result was negative. From 16 DNA of B. holmesii – positive samples, 9 samples were negative in test system earlier, in 2 samples – the doubtful result, 1 sample was earlier identified as DNA of B. parapertussis and in 4 samples DNA of B. pertussis and B. holmesii are found.Conclusion.The research demonstrates circulation of B. holmesii in the territory of Russia that is confirmed by identification of positive samples in 3,8% of cases among the sick children and adults hospitalized in a hospital with suspicion of pertussis and pertussis-like illnesses. For increase in efficiency of laboratory confirmation of the clinical diagnosis of pertussis and pertussis-like illnesses the genodiagnostic of a pertussis is recommended to improve taking into account identification DNA of B. holmesii.
Diagnostic and prognostic laboratory criteria for the development of sepsis in purulent-inflammatory diseases of soft tissues
Authors: Golobokov G. S. , Tsvetkov V. V. , Tokin I. I. , Shejanov S. D. , Levashova A. B. , Lioznov D. A. 
Published: May 2019

Objective. Identification of laboratory parameters that are used in routine practice and can serve as diagnostic and prognostic criteria for the development of sepsis and its outcomes in patients with purulent-inflammatory diseases of soft tissues.Materials and methods. The study included 48 patients with purulent-inflammatory diseases of soft tissues. Recorded the occurrence of such clinical events as the development of sepsis or septic shock, intensive therapy, death or recovery and discharge from the hospital. For the diagnosis of sepsis, a SOFA (Sepsis-related organ failure assessment score) ³ 2 points was used. Patients were divided into subgroups according to the number of points according to the SOFA scale, intensive care and depending on the outcome of the disease: Subgroup 1 – 26 patients with sepsis (SOFA ³ 2 points) and 22 patients with systemic inflammatory response syndrome (SIRS) and SOFA <2 points; 2nd subgroup – 12 people who underwent intensive therapy and 36 people without it; 3rd subgroup – 7 patients with a fatal outcome and 41 patients with a favorable outcome.Results. In patients with sepsis, albumin concentration was 24,07 g / l in median versus 34,65 g / l in the control group of patients with SOFA <2 points (p <0,01); glucose -7,82 mmol / l and 5,15 mmol / l (p <0,01); sodium concentration of 133 mmol / li 139 mmol / l (p <0,01). The values of the international normalized ratio (INR) amounted to a median of 1,29 and 1,04 (p <0,01); activated partial thromboplastin time -36,20 seconds and 31,50 seconds (p <0,01). In the subgroup of patients for whom intensive therapy was required, the concentration of albumin was 22,34 g / l by median versus 30,10 g / l (p <0,01); urea – 15,50 mmol / l versus 6,00 mmol / l (p <0,05), glucose – 9,61 mmol / l against 5,80 mmol / l (p <0,05), lactate dehydrogenase-644,00 U / l and 426,00 U / l (p <0,05); INR – 1,35 against 1,05 (p <0,05). The aver-age total protein concentration is 47,80 g / l versus 57,90 g / l (p <0,01). The average albumin is 22,34 g / l versus 28,50 g / l (p <0,05). The glucose concentration among patients with a fatal outcome was 12,00 mmol / l in median versus 5,95 mmol / l (p <0,01); urea – 23,22 mmol / l versus 6,00 mmol / l (p <0,01). The incidence of lethal disease was statistically significantly higher in patients with a total protein level of less than 52 g / l 5,96 times (RR = 5,96, 95% CI 1,32 – 26,89), glucose more than 11 mmol / l – 7,00 times (OR = 7,00, 95% CI 1,25 – 39,15), urea more than 20 mmol / l – 7,05 times (RR = 7,05, 95% CI 2,00 – 24,85).Conclusion. Routine laboratory indicators as the level of total protein, albumin, glucose, sodium and urea, as well as indicators of the blood coagulation system (INR and APTT), can serve as diagnostic and prognostic criteria for the development of sepsis and its outcomes in patients with purulentinflammatory diseases. soft tissue.
s MadCAM-1 as an immunological marker in the «gut liver axis» at patients with chronic hepatitis C and excess body weight
Authors: Zhdanov K. V. , Semenov A. V. , Karyakin S. S. , Kozlov K. V. , Sukachev V. S. , Ostankova Yu. V. , Valutite D. E. , Zueva E. B. , Sidorov R. S. , Saulevich A. V. , Bulan’kov Yu. I. , Lyashenko Yu. I. , Ivanov K. S. 
Published: May 2019

Background and aims: to estimate concentration of sMadCAM-1 in peripheral blood at patients with chronic hepatitis C with excess body weight.Materials and methods: The research included 88 patients (67 men, 21 women 41.4±3.2 years of age) with chronic hepatitis C (CHC) and excess body weight (the index of body mass is³25 kg/m2, and abdominal circumference more than 94 cm in men, and 80 cm in women) with various morfofunktsionalny changes in a liver and a small bowel. From them men there were 67 people, women – 21, middle age was 41.4±3.2 years.To all the patients complex clinical, biochemical, virologic, morphological trial was carried out. The functional condition of intestines was estimated by identification of a small intestinal bacterial overgrowth (SIBO) when carrying out the hydrogen respiratory test (HRT) with lactulose and existence of endoscopic signs of inflammation of a mucous membrane of intestines at a fibroezofagogastroduodenoskopiya. The quantitative assessment of a mucosal addressin cell adhesion molecule -1 was carried out by the definition concentration of its soluble form (sMadCAM-1) in a blood plasma by enzyme immunoassay method.Results: the sMadCAM-1 level of peripheral blood at the patients with excess body weight increased in process of progressing of a stage of chronic hepatitis C (F0 – 349.10 (324.27-373.92) ng/ml; F1/2 – 439.69 (406.43-472.94) ng/ml; F3/4 – 1057.82 (593.38-1522.26) ng/ml; p˂0.05), existence of a syndrome of excess bacterial growth and endoscopic signsof a duodenitis. Besides, patients had its concentration more with the biochemical signs characterizing cytolytic (at ALT˃N: 502.54 (432.04-573.03) ng/ml against 381.04(345.49-416.58) at the ALT normal values), cholestatic (at GGTP˃N: 550.59 (453.31-647.88) ng/ml against 400.86(365.13-436.59) atnormal GGTP, p values 0.05; at ALP N: 572.2 (353.7-790.8) ng/ml against 468.7 (408.5-528.9) ng/ml at normal ALP, p values 0.05) and metabolic syndromes (at glucose of blood, TG, VLDL N: 562.93 (369.59-756.27) ng/ml, 681.15 (387.81-974.49) ng/ml, 809.65(124.04-1495.28) against (438.34(391.36-485.31) ng/ml), (421.69(379.41-463.97) ng/ml), 434.47(389.45-479.48), p values 0.05 at normal values of these indicators respectively).Conclusion: Progressing of fibrosis and functional disturbances in intestines are interconnected with increase in concentration of MadCAM-1 in blood that allows to consider pathological changes in intestines of various genesis as the accessory factor promoting progressing of СHC at patients with excess body weight. Besides, definition of concentration of sMadCAM-1 in peripheral blood can be used as one of markers of noninvasive diagnostics of a stage of fibrosis at the patients with СHC and excess body weight.
AKTIVITAS ANTIANGIOGENESIS EKSTRAK BERAS HITAM (Oryza sativa L. indica) PADA CHORIOALANTOIC MEMBRANE (CAM) SEBAGAI KANDIDAT ANTIKANKER ANTIANGIOGENESIS ACTIVITY OF BLACK RICE (Oryza sativa L. indica) ON CHORIOALANTOIC MEMBRANE (CAM) AS ANTICANCER CANDIDATE
Authors: Sayekti Fitria Diniah Janah , Taufiq Qurrohman Muhammad 
Published: May 2019

AbstrakAngiogenesis memberikan kontribusi pada karsinogenesis atau pertumbuhan sel kanker yang tidak terkendali. Pertumbuhan tumor atau kanker dapat dikontrol melalui penghambatan angiogenesis. Salah satu bahan alam yang berpotensi sebagai bahan pangan fungsional prevensi kanker adalah beras hitam. Penelitian ini bertujuan untuk mempelajari dan mengetahui aktivitas antiangiogenesis ekstrak beras hitam (Oryza sativa L. indica) pada Chorioallantoic Membrane (CAM) sebagai kandidat antikanker. Parameter yang diamati dalam penelitian adalah banyaknya pembuluh darah baru atau respon angiogenesis pada CAM setelah pemberian ekstrak beras hitam dengan konsentrasi masing-masing 20, 25, 50, 60 dan 75 µg/mL. Ekstrak beras hitam menghambat pembentukan pembuluh darah pada CAM. Rata-rata jumlah pembuluh darah pada konsentrasi ekstrak beras hitam 20, 25, 50, 60 dan 75 µg/mL berturut-turut adalah 27,6; 21,0; 3,67; 3,0; 2,0. Pada kontrol dengan larutan NaCl 0,9 %, jumlah rata-rata pembuluh darah adalah adalah 35,33. Kata Kunci : Beras hitam (Oryza sativa L. indica), angiogenesis, antikanker AbstractAngiogenesis contributes to uncontrolled carcinogenesis or cancer cell growth. Tumor or cancer growth can be controlled through inhibition of angiogenesis. One of the natural ingredients that have the potential as a cancer prevention functional food ingredient is black rice. This study aims to study and determine the antiangiogenesis activity of black rice extract (Oryza sativa L. indica) on the Chorioallantoic Membrane (CAM) as an anticancer candidate. The parameters observed in the study were the number of new blood vessels or the response of angiogenesis to CAM after the administration of black rice extract with a concentration of 20, 25, 50, 60 and 75 µg / mL, respectively. The higher the concentration of black rice extract showed a decrease in the number of blood vessels formed. The average number of blood vessels at concentrations of black rice extract 20, 25, 50, 60 and 75 µg / mL were 27.6; 21.0; 3.67; 3.0; 2.0. In the control with 0.9% NaCl solution, the average number of blood vessels was 35.33. Keywords: Black rice ( Oryza sativa L. indica), angiogenesis, anticancer
UPAYA MENINGKATKAN KETERAMPILAN BERBICARA BAHASA INDONESIA MELALUI PENERAPAN METODE DEBAT PADA SISWA KELAS V SDN 09 MATTEKKO KECEMATAN BARA KOTA PALOPO
Authors: Zainuddin Ni’ma 
Published: May 2019

The research by using the method of debate aims to improve speaking skill on the students of grade V SDN 09 mattekko. This type of research is classroom action research (CAR). The subjects were teachers and students of class V SDN 09 Mattekko Kecamatan Bara Palopo city which amounted to 24, 10 men and 14 women. Research kurt lewin model has four stages of planning, implementation, observation, and reflection. Data collection using objective test method, that is by measuring students' speaking skills and observation method using observation sheet which aims to observe student activity and guidance. Qualitative and quantitative approaches are used to analyze collected data. From the research result of debate method can improve speech skill of class V student SDN 09 Mattekko. This is addressed by an increase in the average value. The number of students reaching the minimum criterion score (MCS) on the preeclosure test is 29.17%, the first cycle is 58.33%, and the second cycle is 95.83%. While the average value of pratindakan 63.75, 68,09 cycle I, and cycle II 77.33. Success in this process can be seen from the liveliness and enthusiasm of students in following the process of learning activities, in this case, students have dared to issue ideas and respond to any existing answers and questions from opposing groups. Keywords:
PENINGKATAN KETERAMPILAN BERBICARA MELALUI PENGGUNAAN MODEL EXAMPLE NON EXAMPLE PADA SISWA KELAS V DI SDN 24 TEMMALEBBA KECAMATAN BARA KOTA PALOPO
Authors: Fitriani Mirna 
Published: May 2019

Penelitian ini menggunakan penelitian tindakan kelas. Bertujuan untuk meningkatkan kemampuan berbicara siswa pada proses pembelajaran dengan menggunakan media gambar yang ada pada lingkungan siswa sehingga mudah untuk berbicara. Pelaksanaan penelitian ini dilakukan 2 siklus, setiap sisklus berlangsung selama dua kali pertemuan. Subjek dalam penelitian ini adalah siswa kelas V di SDN 24 Temmalebba Kecamatan Bara Kota Palopo, yang berjumlah 35 siswa terdiri dari 19 orang laki-laki dan 16 orang perempuan. Teknik pengumpulan data yang dilakukan dalam penelitian ini yaitu wawancara, tes dan pengamatan. Penelitian ini dapat menggunakan sebuah teknik analisis data secara kualitatif dan kuantitatif. Data kualitatif kemudian dianalisis menggunakan teknik analisis deskriptif kualitatif, yaitu cara teknik pengolahan data dengan cara mendeskripsikan hasil data kualitatif meliputi hasil observasi dan catatan dilapangan. Sedangkan data kuantitatif dianalisis dengan menggunakan teknik statistik dalam bentuk perhitungan rata-rata (mean). Hasil penelitian ini menunjukkan bahwa nilai rata-rata keterampilan berbicara siswa meningkat pada tiap siklusnya. Pada prasikls yang nilai rata-ratanya 2,13,meningkat pada siklus I yang nilai rata-ratanya 3,04, dan semakin meningkat pada siklus II yang nilai rata-ratanya 3,77. Kesimpulan dari penelitian ini yaitu dengan menggunaan model example non example maka keterampilan berbicara siswa kelas V di SDN 24 Temmalebba Kec.Bara Kota Palopo dapat meningkat.
Long-term patient satisfaction with implanted device remote monitoring: a comparison among different systems
Authors: Artico Jessica , Zecchin Massimo , Zorzin Fantasia Anna , Skerl Giulia , Ortis Benedetta , Franco Stefania , Albani Stefano , Barbati Giulia , Cristallini Jacopo , Cannata’ Antonio , Sinagra Gianfranco 
Published: May 2019

Aims
Remote monitoring is an effective strategy to improve patients’ outcomes and reduce hospitalization in patients with cardiac implantable electronic devices. However, data on patients’ satisfaction are scarce. The aim of the current study was to assess patients’ satisfaction, ease of use and impact on daily activities of the remote monitoring and to investigate whether there are differences among different devices and different manufacturers.

Methods
A modified Home Monitoring Acceptance and Satisfaction Questionnaire telephone survey on the perceived quality of the different systems was performed with all patients followed with remote monitoring for at least 3 months.

Results
Among 604 patients with remote monitoring screened by telephone, 466 patients (77%) answered the questionnaire [142 patients (30.5%) had a pacemaker, 317 patients (68%) had an implantable cardioverter defibrillator, and seven patients (1.5%) had an implantable loop recorder]. Ninety-seven percent of patients were satisfied by the remote monitoring system during the entire follow-up and found it easy to use. Similarly, 85% of patients did not experience any restriction in daily activities, and for 99% of patients it did not affect their privacy. Importantly, for the vast majority of patients, remote monitoring gave a great (56.7%) or moderate (33.4%) sense of security.

Conclusion
Daily impact of cardiac implantable electronic devices still remains a challenging issue for caregivers. The introduction of remote monitoring allowed closer follow-up and improved outcomes. Our results highlighted patients’ satisfaction, who also felt safer, with the remote monitoring, its ease of use, and the absence of any disturbances in patients’ everyday activities or in their privacy.