bluuebunny/crossref_metadata_2025_split huggingface dataset:
Control of Filth Flies, Cochliomyia macellaria (Diptera: Calliphoridae), Musca domestica (Diptera: Muscidae), and Sarcophaga bullata (Diptera: Sarcophagidae), Using Novel Plant-Derived Methyl Ketones
Authors: Deguenon Jean M , Zhu Jiwei , Denning Steven , Reiskind Michael H , Watson David W , Roe R Michael 
Published: June 2019

AbstractFilth flies live in close proximity to humans and livestock and transmit pathogens. Current control relies on chemical insecticides, and flies can develop resistance to these insecticides. The public is also interested in natural and safer insecticides. Therefore, alternative pesticides compatible with the synanthropic nature of flies are needed. Four plant aliphatic methyl ketones were evaluated for control of adult house flies, Musca domestica L., blow flies, Cochliomyia macellaria (F.), and gray flesh flies, Sarcophaga bullata (Parker). In sealed petri dish assays, 2-heptanone, 2-octanone, 2-nonanone, and 2-undecanone exhibited fumigant activity against house flies with 24-h LC50s of 6.9, 7.5, 8.0, and 9.2 µg/cm3, respectively. Further research focused on undecanone (a U.S. EPA-registered biopesticide). When tested in larger enclosures at 1.7, 2.3, and 2.8 µg/cm3, undecanone provided 60.4, 82.2, and 94.4% house fly mortality; 56.9, 75.6, and 92.5% flesh fly mortality; and 62.1, 84.5, and 97.9% blow fly mortality, respectively, after a 2-h exposure. In a two-choice behavioral assay with 194.6 µg/cm2 of the test compound on the treatment versus an untreated surface of the same area, the overall mean repellencies for blow flies were 84.7% for undecanone versus 87.6% for N,N-diethyl-meta-toluamide (DEET). For house flies, mean repellencies were 80.7% for undecanone and 84.9% for DEET. The house fly topical LD50 for undecanone was 58.1 µg per fly. Undecanone was far less expensive for filth fly control than the gold standard for insect fumigation, methyl bromide.
Late Soft Tissue Complications of Head and Neck Cancer Therapy: Lymphedema and Fibrosis
Authors: Deng Jie , Wulff-Burchfield Elizabeth M , Murphy Barbara A 
Published: June 2019

Abstract
Head and neck cancer and its treatment result in soft tissue damage secondary to lymphedema and fibrosis. Lymphedema is the result of pathological accumulation of interstitial fluid in tissues. It is caused by the inability of the lymphatic system to transport lymph fluid from the tissues to the central circulatory system and is manifested clinically by tissue swelling. Fibrosis is defined as an overaccumulation of fibrotic tissues within the skin and soft tissues after a single or repetitive injury and is characterized by hardening of the soft tissues with associated loss of elasticity. Lymphedema and fibrosis are common yet overlooked late effects of head and neck cancer and its therapy. They may result in profound long-term symptom burden, loss of critical functions, and altered quality of life. The following review will discuss the current pathobiology, clinical manifestations, and future directions for research related to lymphedema and fibrosis.
A Paradox of Evidential Equivalence
Authors: Builes David 
Published: June 2019

AbstractOur evidence can be about different subject matters. In fact, necessarily equivalent pieces of evidence can be about different subject matters. Does the hyperintensionality of ‘aboutness’ engender any hyperintensionality at the level of rational credence? In this paper, I present a case which seems to suggest that the answer is ‘yes’. In particular, I argue that our intuitive notions of independent evidence and inadmissible evidence are sensitive to aboutness in a hyperintensional way. We are thus left with a paradox. While there is strong reason to think that rational credence cannot make such hyperintensional distinctions, our intuitive judgements about certain cases seem to demand that it does.
Carbon-chain molecules in molecular outflows and Lupus I region – new producing region and new forming mechanism
Authors: Wu Yuefang , Liu Xunchuan , Chen Xi , Lin Lianghao , Yuan Jinghua , Zhang Chao , Liu Tie , Shen Zhiqiang , Li Juan , Wang Junzhi , Qin Sheng-Li , Kim Kee-Tae , Liu Hongli , Zhu Lei , Madones Diego , Inostroza Natalia , Henkel Christian , Zhang Tianwei , Li Di , Esimbek Jarken , Liu Qinghui 
Published: June 2019

Abstract
Using the new equipment of the Shanghai Tian Ma Radio Telescope, we have searched for carbon-chain molecules (CCMs) towards five outflow sources and six Lupus I starless dust cores, including one region known to be characterized by warm carbon-chain chemistry (WCCC), Lupus I-1 (IRAS 15398-3359), and one TMC-1 like cloud, Lupus I-6 (Lupus-1A). Lines of HC3N J = 2 − 1, HC5N J = 6 − 5, HC7N J = 14 − 13, 15 − 14, 16 − 15, and C3S J = 3 − 2 were detected in all the targets except in the outflow source L1660 and the starless dust core Lupus I-3/4. The column densities of nitrogen-bearing species range from 1012 to 1014 cm−2 and those of C3S are about 1012 cm−2. Two outflow sources, I20582+7724 and L1221, could be identified as new carbon-chain-producing regions. Four of the Lupus I dust cores are newly identified as early quiescent and dark carbon-chain-producing regions similar to Lup I-6, which together with the WCCC source, Lup I-1, indicate that carbon-chain-producing regions are popular in Lupus I which can be regard as a Taurus-like molecular cloud complex in our Galaxy. The column densities of C3S are larger than those of HC7N in the three outflow sources I20582, L1221, and L1251A. Shocked carbon-chain chemistry is proposed to explain the abnormal high abundances of C3S compared with those of nitrogen-bearing CCMs. Gas-grain chemical models support the idea that shocks can fuel the environment of those sources with enough S+ thus driving the generation of S-bearing CCMs.
Transverse kinematics of the Galactic bar-bulge from VVV and Gaia
Authors: Sanders Jason L , Smith Leigh , Evans N Wyn , Lucas Philip 
Published: June 2019

ABSTRACT
We analyse the kinematics of the Galactic bar-bulge using proper motions from the ESO public survey Vista Variables in the Via Lactea (VVV) and the second Gaia data release. Gaia has provided some of the first absolute proper motions within the bulge and the near-infrared VVV multi-epoch catalogue complements Gaia in highly extincted low-latitude regions. We discuss the relative-to-absolute calibration of the VVV proper motions using Gaia. Along lines of sight spanning $-10\lt \ell /\, \mathrm{deg}\lt 10$ and $-10\lt b/\, \mathrm{deg}\lt 5$, we probabilistically model the density and velocity distributions as a function of distance of ∼45 million stars. The transverse velocities confirm the rotation signature of the bar seen in spectroscopic surveys. The differential rotation between the double peaks of the magnitude distribution confirms the X-shaped nature of the bar-bulge. Both transverse velocity components increase smoothly along the near side of the bar towards the Galactic Centre, peak at the Galactic Centre, and decline on the far side. The anisotropy is σℓ/σb ≈ 1.1–1.3 within the bulk of the bar, reducing to 0.9–1.1 when rotational broadening is accounted for, and exhibits a clear X-shaped signature. The vertex deviation in ℓ and b is significant |ρℓb| ≲ 0.2, greater on the near side of the bar and produces a quadrupole signature across the bulge indicating approximate radial alignment. We have re-constructed the 3D kinematics from the assumption of triaxiality, finding good agreement with spectroscopic survey results. In the co-rotating frame, we find evidence of bar-supporting x1 orbits and tangential bias in the in-plane dispersion field.
Rotational quenching of HD induced by collisions with H2 molecules
Authors: Wan Yier , Balakrishnan N , Yang B H , Forrey R C , Stancil P C 
Published: June 2019

ABSTRACT
Rate coefficients for rotational transitions in HD induced by H2 impact for rotational levels of HD j ≤ 8 and temperatures 10 K ≤ T ≤ 5000 K are reported. The quantum mechanical close-coupling (CC) method and the coupled-states (CS) decoupling approximation are used to obtain the cross-sections employing the most recent highly accurate H2–H2 potential energy surface (PES). Our results are in good agreement with previous calculations for low-lying rotational transitions The cooling efficiency of HD compared with H2 and astrophysical applications are briefly discussed.
No signs of star formation being regulated in the most luminous quasars at z ∼ 2 with ALMA
Authors: Schulze Andreas , Silverman John D , Daddi Emanuele , Rujopakarn Wiphu , Liu Daizhong , Schramm Malte , Mainieri Vincenzo , Imanishi Masatoshi , Hirschmann Michaela , Jahnke Knud 
Published: June 2019

ABSTRACT
We present ALMA Band 7 observations at $850\, \mu$m of 20 luminous ($\log \, L_{\rm bol}\,\gt\, 46.9$ [erg s−1]) unobscured quasars at z ∼ 2. We detect continuum emission for 19/20 quasars. After subtracting an AGN contribution, we measure the total far-IR luminosity for 18 quasars, assuming a modified blackbody model, and attribute the emission as indicative of the star formation rate (SFR). Our sample can be characterized with a lognormal SFR distribution having a mean of 140 M⊙ yr−1 and a dispersion of 0.5 dex. Based on an inference of their stellar masses, the SFRs are similar, in both the mean and dispersion, with star-forming main-sequence galaxies at the equivalent epoch. Thus, there is no evidence for a systematic enhancement or suppression (i.e. regulation or quenching) of star formation in the hosts of the most luminous quasars at z ∼ 2. These results are consistent with the Magneticum cosmological simulation, while in disagreement with a widely recognized phenomenological model that predicts higher SFRs than observed here based on the high bolometric luminosities of this sample. Furthermore, there is only a weak relation between SFR and accretion rate on to their supermassive black holes both for average and individual measurements. We interpret these results as indicative of star formation and quasar accretion being fed from the available gas reservoir(s) in their host with a disconnect due to their different physical sizes, temporal scales, and means of gas processing.
The full evolution of supernova remnants in low- and high-density ambient media
Authors: Jiménez Santiago , Tenorio-Tagle Guillermo , Silich Sergiy 
Published: June 2019

ABSTRACT
Supernova explosions and their remnants (SNRs) drive important feedback mechanisms that impact considerably the galaxies that host them. Then, the knowledge of the SNRs evolution is of paramount importance in the understanding of the structure of the interstellar medium and the formation and evolution of galaxies. Here, we study the evolution of SNRs in homogeneous ambient media from the initial, ejecta-dominated phase, to the final, momentum-dominated stage. The numerical model is based on the Thin-Shell approximation and takes into account the configuration of the ejected gas and radiative cooling. It accurately reproduces well-known analytic and numerical results and allows one to study the SNR evolution in ambient media with a wide range of densities n0. It is shown that in the high-density cases, strong radiative cooling alters noticeably the shock dynamics and inhibits the Sedov-Taylor stage, thus limiting significantly the feedback that SNRs provide to such environments. For n0 > 5 × 105 cm−3, the reverse shock does not reach the centre of the explosion due to the rapid fall of the thermal pressure in the shocked gas caused by strong radiative cooling.
Time-average properties of z ∼ 0.6 major mergers: mergers significantly scatter high-z scaling relations
Authors: Puech M , Flores H , Rodrigues M , Hammer F , Yang Y B 
Published: June 2019

Abstract
Interpreting the scaling relations measured by recent large kinematic surveys of z ≲ 1 galaxies has remained hampered by large observational scatter. We show that the observed ISM and morpho-dynamical properties along the average z ∼ 0.6 major merger describe a very self-consistent picture in which star formation is enhanced during first passage and fusion as a result of gravitational perturbations due to the interaction, while the gas velocity dispersion is simultaneously enhanced through shocks that convert kinematic energy associated with bulk orbital motions into turbulence at small scales. Angular momentum and rotation support in the disc are partly lost during the most perturbing phases, resulting in a morphologically compact phase. The fractions of present-day E/S0 versus later type galaxies can be predicted within only a few per cent, confirming that roughly half of local discs were reformed in the past 8–9 Gyr after gas-rich major mergers. Major mergers are shown to strongly scatter scaling relations involving kinematic quantities (e.g. the Tully–Fisher or Fall relations). Selecting high-z discs relying only on V/σ turns out to be less efficient than selecting discs from multiple criteria based on their morpho-kinematic properties, which can reduce the scatter of high-z scaling relations down to the values measured in local galaxy samples.
Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs
Authors: Shinoda Saori , Kitagawa Sho , Nakagawa Shinichi , Wei Fan-Yan , Tomizawa Kazuhito , Araki Kimi , Araki Masatake , Suzuki Takeo , Suzuki Tsutomu 
Published: June 2019

AbstractPost-transcriptional modifications in mitochondrial tRNAs (mt-tRNAs) play critical roles in mitochondrial protein synthesis, which produces respiratory chain complexes. In this study, we took advantage of mass spectrometric analysis to map 5-methylcytidine (m5C) at positions 48–50 in eight mouse and six human mt-tRNAs. We also confirmed the absence of m5C in mt-tRNAs isolated from Nsun2 knockout (KO) mice, as well as from NSUN2 KO human culture cells. In addition, we successfully reconstituted m5C at positions 48–50 of mt-tRNA in vitro with NSUN2 protein in the presence of S-adenosylmethionine. Although NSUN2 is predominantly localized to the nucleus and introduces m5C into cytoplasmic tRNAs and mRNAs, structured illumination microscopy clearly revealed NSUN2 foci inside mitochondria. These observations provide novel insights into the role of NSUN2 in the physiology and pathology of mitochondrial functions.
Cost-effectiveness of four living-donor nephrectomy techniques from a hospital perspective
Authors: Achit Hamza , Guillemin Francis , Karam Georges , Ladrière Marc , Baumann Cedric , Frimat Luc , Hosseini Kossar , Hubert Jacques 
Published: June 2019

Abstract

Background
In Europe, transplantation centres use different nephrectomy techniques: open surgery, and standard, hand-assisted and robot-assisted laparoscopies. Few studies have analysed the disparity in costs and clinical outcomes between techniques. Since donors are healthy patients expecting minimum pain and fast recovery, this study aimed to compare the cost-effectiveness of four nephrectomy techniques focusing on early surgical outcomes, an essential in the donation act.

Methods
A micro-costing approach was used to estimate the cost of implementation from a hospital perspective. Estimates took into account sterilization costs for multiple-use equipment, costs for purchasing single-use equipment, staff and analgesics. The study recruited donors in 20 centres in France. Quality of life by EuroQol-5D was assessed preoperatively, and 4 and 90 days post-operatively. Two effectiveness indicators were built: quality-of-life recovery and post-operative pain days averted (PPDA). The study was registered at ClinicalTrials.gov NCT02830568, on 10 June 2010.

Results
A total of 264 donors were included; they underwent open surgery (n = 65), and standard (n = 65), hand-assisted (n = 65) and robot-assisted laparoscopies (n = 69). Use of the nephrectomy techniques differed greatly in cost of implementation and immediate post-operative outcomes but not in clinical outcomes at 90 days. At 4 days, hand-assisted laparoscopy provided the lowest cost per quality-of-life recovery unit of effectiveness (%) and PPDA (days) (€2056/40.1%/2.3 days, respectively). Robot-assisted laparoscopy was associated with the best post-operative outcomes but with the highest cost (€3430/59.1%/2.6 days).

Conclusion
Hand-assisted, standard and robot-assisted laparoscopies are cost-effective techniques compared with open surgery. Hand-assisted surgery is the most cost-effective procedure. Robot-assisted surgery requires more healthcare resource use but enables the best clinical outcome.
Are there Still Limits on Partisan Prejudice?
Authors: Westwood Sean J , Peterson Erik , Lelkes Yphtach 
Published: June 2019

Abstract
Partisan affective polarization is believed, by some, to stem from vitriolic elite political discourse. We explore this account by replicating several 2014 studies that examine partisan prejudice. Despite claims of elevated partisan affective polarization from pundits, this extensive replication offers no evidence of an increase in the public’s partisan prejudice between 2014 and 2017. Divides in feeling thermometer ratings of the two political parties remained stable, and there was no overall increase in measures of partisan prejudice between periods. This is consistent with results from the 2012 and 2016 ANES. Moreover, the most affectively polarized members of the public became no more likely to hold prejudicial attitudes toward the other party. Despite an intervening campaign with elevated elite hostility and rampant postelection discord, the limits on partisan prejudice identified in prior research remain in place. This stability is important for understanding the nature and malleability of partisan affect.
Awareness of product-related information, health messages and warnings on alcohol packaging among adolescents: a cross-sectional survey in the United Kingdom
Authors: Critchlow Nathan , Jones Daniel , Moodie Crawford , MacKintosh Anne Marie , Fitzgerald Niamh , Hooper Lucie , Thomas Christopher , Vohra Jyotsna 
Published: June 2019

Abstract

Background
Alcohol packaging can be used to communicate product-related information, health messages and health warnings to consumers. We examined awareness and recall of such information and messaging among adolescents in the United Kingdom.

Method
A cross-sectional survey was conducted with 11–19 year olds in the United Kingdom (n = 3399), with participants asked if they had seen any information, health messages or warnings on alcohol packaging in the past month (Yes/No) and, if so, what they recalled. We also assessed higher-risk drinking among current drinkers (≥5 Alcohol Use Disorders Identification Test-Consumption) and susceptibility to consume among never-drinkers.

Results
One-third (32%) of participants had seen information, health messages or warnings on alcohol packaging. Chi-Square tests showed awareness was greater for current drinkers than non-drinkers (46% vs. 19%; P &lt; 0.001), higher-risk drinkers than lower-risk drinkers (55% vs. 39%; P &lt; 0.001), and susceptible never-drinkers than non-susceptible never-drinkers (21% vs. 16%; P = 0.01). Ten messages were recalled, with drinking responsibly (18%) and not drinking during pregnancy (13%) most recalled.

Conclusion
Most young drinkers, including almost half of higher-risk drinkers, did not recall seeing any information, health messages or warnings on alcohol packaging in the past month, suggesting that current labelling is failing to reach this key audience.
Do Financial Regulations Shape the Functioning of Financial Institutions’ Risk Management in Asset-Backed Securities Investment?
Authors: Chen Xuanjuan , Higgins Eric , Xia Han , Zou Hong 
Published: June 2019

AbstractWe show that installing stronger risk management into financial institutions—a proposal widely discussed following the 2008 financial crisis—is insufficient to constrain institutions’ exposure to investment with lurking risk, such as asset-backed securities (ABS). Regulations affect the functioning of risk management: risk management constrains institutions’ exposure to risky ABS when they face mark-to-market reporting combined with capital requirements; however, this role is considerably weaker when capital requirements are combined with historical cost accounting. We find suggestive evidence that financial regulations affect risk management functions through promoting risk managers’ efforts in uncovering ABS risk and curbing executives’ incentives to take excessive risk.Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.
Asking ‘why?’ enhances theory of mind when evaluating harm but not purity violations
Authors: Dungan James A , Young Liane 
Published: June 2019

Abstract
Recent work in psychology and neuroscience has revealed important differences in the cognitive processes underlying judgments of harm and purity violations. In particular, research has demonstrated that whether a violation was committed intentionally vs accidentally has a larger impact on moral judgments of harm violations (e.g. assault) than purity violations (e.g. incest). Here, we manipulate the instructions provided to participants for a moral judgment task to further probe the boundary conditions of this intent effect. Specifically, we instructed participants undergoing functional magnetic resonance imaging to attend to either a violator’s mental states (why they acted that way) or their low-level behavior (how they acted) before delivering moral judgments. Results revealed that task instructions enhanced rather than diminished differences between how harm and purity violations are processed in brain regions for mental state reasoning or theory of mind. In particular, activity in the right temporoparietal junction increased when participants were instructed to attend to why vs how a violator acted to a greater extent for harm than for purity violations. This result constrains the potential accounts of why intentions matter less for purity violations compared to harm violations and provide further insight into the differences between distinct moral norms.
Cytokines and chemokines triggered by Chikungunya virus infection in human patients during the very early acute phase
Authors: Tanabe Ithallo S B , Santos Elane C , Tanabe Eloiza L L , Souza Stephannie J M , Santos Fabio E F , Taniele-Silva Jamile , Ferro Jean F G , Lima Magliones C , Moura Adriana A , Anderson Leticia , Bassi Ênio J 
Published: June 2019

Abstract

Background
The immune response against the Chikungunya virus (CHIKV) during the very early acute phase is not fully elucidated. Therefore we explored the cytokine and chemokine profile triggered by CHIKV in infected patients.

Methods
Cytokines, chemokines and C5a anaphylatoxin were analysed in serum from CHIKV-infected patients during the viraemic phase (mean 2.97±1.27 d after illness onset) compared with a healthy group.

Results
CHIKV-infected patients had a significant increase of interferon-α (IFN-α), interleukin-6 (IL-6), interleukin-8 (CXCL8/IL-8), interleukin-10 (IL-10), interferon-γ (IFN-γ), monokine induced by interferon-γ (CXCL9/MIG), monocyte chemoattractant protein-1 (CCL2/MCP-1), interferon-γ-induced protein-10 (CXCL10/IP-10) and complement C5a anaphylatoxin.

Conclusions
The very early acute immune response triggered against CHIKV leads to an increase in pro-inflammatory immune mediators such as IFN-γ and its induced chemokines, and a high level of C5a anaphylatoxin as a result of complement activation.