bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMPARISON OF EFICIENCY OF NEW PHARMACOLOGICAL COMPOSITION AND OINTMENTS ACYCLOVIR FOR TREATING HERPETIC GINGIVOSTOMATITIS
Authors: Мандра Ю. , Mandra J. , Ваневская Е. , Vanevskaya E. 
Published: August 2018

<p>The new pharmaceutical composition for the treatment of herpetic gingivostomatitis was synthesized. It contains an antiviral ingredient Triazavirin. The base of composition is silicone glycerohydrogel. The purpose of research - clinical and laboratory study and compare the efficacy of a new pharmaceutical composition and Acyclovir ointment in complex treatment of herpetic gingivostomatitis. The study group № 1 was presented 53 patients, study group № 2 was 54. All patients were assigned to a comprehensive treatment of herpetic gingivostomatitis. We use a new pharmaceutical composition in the study group № 1 and traditional local antiviral drug acyclovir ointment 5% in the study group number 2. It is well established that the effectiveness of a new pharmaceutical composition in the complex treatment of herpetic gingivostomatitis higher than when using conventional antiviral drug acyclovir. Results are supported by basic and advanced techniques. </p>
CORECTION OF ENZYMATIC AND MICROELEMENT IMBALANCE IN THE ORAL CAVITY DURING THE ENT DISEASES
Authors: Гурцкая Н. , Gurtskaya N. 
Published: August 2018

<p>The result of research 50 patients with upper respiratory tract finds out immune deficiency, which developed in the organs and tissues of the oral cavity of the examined patients. When conducting clinical and laboratory studies have established intensive increase MDA level and decrease the level and SOD activity in the saliva of the examined patients suffering from concomitant ENT pathologies and periodontal diseases. Thus, it should be noted that deficiency and imbalance of calcium, phosphorus in saliva in patients with studied pathology may result serious pathogenic metabolic and structural changes in tissues and organs of the oral cavity. This confirms a significant increase secretors Immunoglobulin levels in saliva at the early stages of treatment when using herbal medicines. MDA content more pronounced, respectively decreased after treatment and preventive measures at the use of combined herbal preparation «Faqolin» as compared with the other groups of patients. </p>
EXPERIENCE OF QUARTZ REINFORCING MESH FOR ORTHOPEDIC REHABILITATION PATIENT WITH MIKROSTOMIEY
Authors: Карасева В. , Karaseva V. 
Published: August 2018

<p>Quite often as a result of injuries prirotovoy area in surgery for tumors and facial burns formed narrowing mouth slit – mikrostomiya. Scarring of the tissues surrounding the mouth slit prevent opening of the mouth and reduce mouth slit, making the treatment, removal and subsequent prosthetics highly problematic. On an example of a clinical case features dismantled manufacturing denture on mandible in a patient with this disease and ways to solve the problems of adaptation and frequent breakdowns of the prosthesis by using reinforcing mesh quartz. The estimation results of the orthopedic treatment. </p>
CONE-BEAM COMPUTED TOMOGRAPHY IN PEDIATRIC DENTISTRY: A REVIEW OF CURRENT LITERATURE
Authors: Фанакин В. , Fanakin V. , Бутюгин И. , Butyugin I. , Батанова Е. , Batanova E. 
Published: August 2018

<p>The use of cone beam computed tomography (CBCT) in paediatric dentistry has been mentioned in numerous publications and case reports. The indications for the use of CBCT in paediatric dentistry, however, have not yet been properly addressed. On the other hand, the three basic principles of radiation protection (justification, limitation and optimisation) should suffice. A review of the current literature was used to assess the indications and contra-indications for the use of CBCT in paediatric dentistry. Paramount is the fact that CBCT generates a higher effective dose to the tissues than traditional dental radiographic exposures do. The effective radiation dose should not be underestimated, especially not in children, who are much more susceptible to stochastic biological effects. The thyroid gland in particular should be kept out of the primary beam as much as possible. As with any other radiographical technique, routine use of CBCT is not acceptable clinical practice. CBCT certainly has a place in paediatric dentistry, but its use must be justified on a patient case individual basis. </p>
THE STATE OF MICROBIOCENOSIS IN PATIENTS WITH VARIOUS DISEASES OF THE ORAL MUCOSA
Authors: Бондаренко О. , Bondarenko O. , Токмакова С. , Tokmakova S. , Шестун К. , Shestun K. , Киселева К. , Kiseleva K. 
Published: August 2018

<p>Changes of the microbiocenosis is a highly informative indicator of the body in general and dental system in particular. The factors leading to the violation of microflora, varied. There is information about its violation in various pathological conditions against the background of reduced immunobiological reactivity with accompanying diseases, including oral mucosa. We studied the microbiocenosis in patients with various diseases of oral mucosa. It is revealed, that on a background of growth of pathogenic and conditionally pathogenic microflora to the etiological of significant digits is a reduction in the prevalence of normal. Successful elimination of dysbacteriosis in complex therapy of oral mucosa diseases may improve the results of treatment of the primary disease. </p>
COMPARATIVE EVALUATION OF EDGE PENETRATION SEALING MATERIALS USED FOR RETROGRADE ROT CANAL TETH (LABORATORY STUDY )
Authors: Токмакова С. , Tokmakova S. , Луницына Ю. , Lunitsyna Y. 
Published: August 2018

<p>Therapeutic endodontic treatment is not always possible for various reasons. There is need for methods of endodontic surgery, particularly retrograde filling. Actual direction is to study the efficiency of the use of a filling material for root canals of teeth roots. We have experimentally studied the apical mikropermeability filling materials «MTA ProRoot», «Trioksident», «Rutdent», «Biodentine», «Ketac Cem»; proven advantage calcium materials to glass ionomer cements. </p>
ATROPHY , BONE -GRAFTING AND IMPLANTATION : CONCEPT
Authors: Полупан П. , Polupan P. 
Published: August 2018

<p>The author on the basis of clinical experience analyses the effectiveness of common bone substitutes and reviews prospects of other bone-grafting methods. It is offered to use minimum of enthetic materials, also the advantages of using single-stage protocol and one-phase implants are shown as compared to generally accepted methods in case of the atrophy of the alveolar ridge. Article also supports the concept of conservation of natural teeth. </p>
A SOCIAL ASPECTS OF RENDERING THE DENTAL TREATMENT TO CHILDREN IN YEKATERINBURG
Authors: Рублева И. , Rubleva I. , Митрофанова К. , Mitrofanova K. , Закиров Т. , Zakirov T. 
Published: August 2018

<p>Studying of satisfaction by a dental treatment of children of 130 people is carried out. 54% of families belong to socially – vulnerable group of the population, 42,5% of respondents aren’t able to afford medical services as it will seriously affect the budget of their family. Only 23,8% of children are treated completely free of charge, the others are compelled to pay dental treatment. Thus, parents of disabled children and parents from large families have low satisfaction with provided medical care in the field of stomatology </p>
IMPROVING THE QUALIT Y OF AESTHETIC RESTORATION ANTERIOR TETH WITH DENTAL PARAMETERS INTO ACOUNT DIFERENCES CAUCASIANS TAJIK AND RUSIAN NATIONALITIES
Authors: Токмакова С. , Tokmakova S. , Луницына Ю. , Lunizyna Y. , Онищенко М. , Onishchenko M. 
Published: August 2018

<p>Creating individual characteristics of teeth for maximum aesthetic effect is impossible without taking into account the individual’s race. Along with common morphological features described in dentistry, there are many features, parts, ratios and forms the surface, giving a person individuality, originality, which must be considered in their work the dentist. The study established differences aesthetic parameters anterior teeth in representatives of the Tajik and Russian nationalities. The article describes odontometricheskie characteristics that can take advantage of a dentist in their practical work. </p>
The influence of recombinant cytokines local application on the course and outcome of closed sinus lift dental implantation
Authors: Латюшина Л. , Latyushina L. , Пиотрович А. , Piotrovich A. , Долгушин И. , Dolgushin I. 
Published: August 2018

<p class="p1"><span class="s1">In order to increase the bone height in the distal portions of the maxilla during dental implantation the method of «closed» sinus lift is widely applied. Manipulation is considered to be a minimally invasive osteotomy but despite this fact, it is associated with a high complication rate that might lead to the loss of the dental implant. </span></p><p class="p1"><span class="s1">The purpose of the project is to analyze the evaluation of the effectiveness of immunomodulators local application during the "closed" sinus lift manipulation that is based on local in uence of «Betaleukin» and «Roncoleukin» drugs in the area of unexpected perforation of the mucous membrane of the maxillary sinus during the formation of the bone bed and close contact surface of the implant with a damaged part. A clinical randomized trial was held which of 105 patients aged 30 to 57, divided into three groups: comparison group, n = 35 (implants placed by the closed sinus lift standard method); betaleukin group, n = 35 (in addition to the surgery performed local recombinant IL-1β immunotherapy was conducted); roncoleukin group, n = 35 (the surgery done was combined with the local ronkoleukine immunomodulation). Within 10-12 days after the surgery hydrogel «Koleteks-Beta» and a gel containing recombinant IL-2 for a local effect on the oral mucous membrane around the installed implant were applied. During the study, all patients had a number of clinical signs that allow assessing the dynamics of post-operative course of the integration process of implants. Radiological control in the postoperative period was conducted to evaluate the position of the implant in relation to the maxillary sinus; the dynamics of bone tissue around it was observed. It was found out that the local treatment by immunomodulators improves the performance dynamics of clinical postoperative period; it reduces the risk of graft rejection and increases the ef ciency of integration process. </span></p>
Defects in the work of dentists in the compulsory health insurance system
Authors: Лебедянцев В. , Lebedjancev V. , Кочкина Н. , Kochkina N. , Полякова Е. , Poljakova E. , Камалитдинова Н. , Kamalitdinova N. 
Published: August 2018

<p class="p1"><span class="s1">With the aim of determining the leveland further improving the quality of dental care in the CHI system the defects of the work of dentists in urban and rural health centers and private clinics were analyzed on the basis of study of 5762 cases of patients by examining the medical records of dental patients. Defects were found in 17.4% of cases, 74.3% of them improper execution of documentation, 25.7% beingdefects inof medical care. The percentage of violations committed in urban public health centers amounts to 9%, in the dental branch of ces of the rural central district hospitals (CDH) it isas high as 18%,while in private clinicsit takes 21% of all cases of treatment of patients. Among the improper execution of documentation defects more common ones are those preventingcarrying out expert examination: 79.1% in government urban clinics, 74.6% in the Central District Hospitals, 49.2% in private clinics. The Signs of medical records falsi cationturned out to be more common in private clinics (31.7% of all improper execution of documentation defects). In 19.4% of the cases studied in all kinds of hospitals there was found a mismatchof the datain the register of invoices for payment, i. e. falsi cation of records Medical care defects in public clinics did not appear to affect the health of the patients. In private clinics 32.7% of defects were of a type leading to the ahealthdeterioration of,or creating the risk of a new disease or prolongingthe highly costly treatment.Nearly half (43%) of dentist work-related defects had to do with the desire to increase the pro t from of CHI fundsmedical services payment. </span></p>
Estimation of possibilities of the cone-beam computed tomography and panoramic tomography in diagnostics of radiopack lesions in the maxillo-facial region
Authors: Блинов В. , Blinov V. , Карташов М. , Kartashov M. , Жолудев С. , Zholudev S. , Зорникова О. , Zornikova O. 
Published: August 2018

<p class="p1"><span class="s1">The purpose of the study was to assess the diagnostic possibilities and interobserver agreement between the radiologist the CBCT and panoramic tomography in diagnostics of radiopack lesions in the maxillo-facial region. The study design: the results of morphological and radial examination of 272 patients with radiopack lesions in the maxillo-facial region were assessed. Consistency among the radiologists was evaluated by means of Cohen»s kappa. The diagnostic signi cance of the results was assessed using Student»s t-test. Results: CBCT sensitivity was 98%, speci city – 89%, diagnostic accuracy – 97%. Sensitivity of the panoramic tomography of the dental alignments was 69%, speci city – 44%, diagnostic accuracy – 64%. The area under the ROC-curve for the panoramic tomography – 0,612 (p˂0,05), for the CBCT – 0,937 (p˂0,05). Interobserver agreement in estimating the panoramic tomography was satisfactory (k=0,24, p˂0,001), it was high for the CBCT (k=0,83, p˂0,0001). </span></p>
Arte na Era do Antropoceno
Authors: Johas Regina 
Published: August 2018

ResumoPartindo das questões tratadas no Projeto Rotas Esquecidas, o artigo trata a relação entre arte e natureza nesta nova era geológica, denominada Antropoceno. Determinado por destrutivas transformações ambientais, o Antropoceno figura no centro das discussões políticas e ecológicas que procuram entender como evitar ou como se adaptar aos seus impactos. Esta nova terminologia, assimilada em outras áreas do conhecimento, passou a fazer parte do discurso das humanidades e das artes, aparecendo em práticas culturais, na produção de artistas, em exposições e em publicações específicas sobre o assunto. Trata-se de avaliar aqui as implicações ideológicas deste termo e de como ele vem sendo tratado no meio artístico. AbstractStarting from the issues addressed in the Project “Rotas Esquecidas”, this paper deals with the relationship between art and nature in this new geological age, called Anthropocene. Determined by destructive environmental transformations, the Anthropocene is at the center of political and ecological discussions that seek to understand how to avoid or how to adapt to its impacts. This new terminology, assimilated in other areas of knowledge, became part of the discourse of the humanities and the arts, appearing in cultural practices, in the production of artists, in exhibitions and in specific publications on the subject. It is a question of evaluating here the ideological implications of this term and how it has been treated in the artistic world.
UMA COMPARAÇÃO DE PRÁTICAS EXPLANATÓRIAS DO MENTALISMO E DA ANÁLISE DO COMPORTAMENTO
Authors: Moore Jay 
Published: August 2018

O mentalismo é uma orientação à explicação causal do comportamento em que as causas são inferidas como estruturas não observáveis, pertencentes a domínios não comportamentais. Tipicamente, essas estruturas são tidas como subjacentes ao comportamento, e o domínio em questão é o da “mente”. Em alguns casos, com algumas exceções, o mentalismo dialoga com a psicologia tradicional ou com o dualismo de substância. Os argumentos em prol das explicações mentais subscritos aos níveis teórico e conceitual não levam em consideração a fonte das referidas explicações. A análise do comportamento se opõe ao mentalismo por razões pragmáticas, ao invés de ontológicas: o mentalismo impede uma análise do comportamento genuína, que possa contribuir no âmbito da previsão e do controle, por confundir os cientistas ao induzi-los a aceitar explicações inefetivas acerca do seu objeto de estudo.Palavras-chave: análise do comportamento, explicação, mentalismo, método científico, comportamento verbal
ANÁLISE DO COMPORTAMENTO E PRAGMATISMO
Authors: Moore Jay 
Published: August 2018

Para o pragmatismo, o significado de um conceito ou afirmação psicológica é encontrado em suas implicações práticas para os assuntos humanos. Não há qualquer suposição de que o conceito ou afirmação representa a Verdade sobre uma Realidade metafísica que está além da experiência e do comportamento humano. Os analistas do comportamento abraçam o pragmatismo e argumentam que uma consideração importante na psicologia é o grau em que um conceito ou afirmação psicológica contribui para uma ação efetiva no laboratório ou na prestação de serviços. A ação efetiva comumente assume a forma de previsão e controle.Palavras-chave: pragmatismo, previsão e controle, mentalismo, níveis de análise, neurociência.
Assessment of muscle and fat mass in type 2 diabetes mellitus patients by dual-energy X-ray absorptiometry
Authors: Misnikova I. V. , Kovaleva Yu. A. , Klimina N. A. , Polyakova E. Yu. 
Published: August 2018

Background:Obesity is an important health problem, as its prevalence has reached an epidemic level and continues to increase steadily resulting in higher risk of cardiovascular diseases and metabolic disorders. Currently, new methods and criteria are being developed to assess fat and muscle mass, as well as criteria for diagnosing obesity and sarcopenia.Aim:To assess the quantitative composition of muscle and adipose tissue in type 2 diabetes mellitus patients based on the dual-energy X-ray absorptiometry for the diagnosis of obesity and sarcopenia.Materials and methods: We examined 42 type 2 diabetic in-patients admitted to the Department of Therapeutic Endocrinology. Dual-energy X-ray absorptiometry was performed in all patients with subsequent assessment of the composition of muscle and fat tissue.Results:If assessed by the body mass index, all patients had an excess body weight: median, 32.25 [29.75; 35.70]; in men, 31.3 [28.19; 34.63], in women, 32.29 [30.26; 36.54]. 26.2% of the patients (11/42) were overweight, but not obese. Female patients had more severe obesity than male (in total, 33.3% (10/30) of women had 2ndand 3rd degree of obesity, while men 16.7% (2/12)). The assessment by the fat mass index (FMI) showed that 2.4% (1/42) of the patients were normal-weight. Median FMI was 11.91 [10.40; 13.78] (in men, 8.86 [7.46; 12.1], in women, 12.35 [11.55; 15.47]). Overweight was found in 52.4% (22/42) of the patients; in total, 2ndand 3rddegree of obesity was observed in 25% (3/12) of the men and only in 6.6% (2/30) of the women. Median Appendicular Lean Mass Index (ALMI) in the total group was 7.99 [7.32; 9.05], being expectedly higher than in women: 9.19 [8.42; 9.45] and 7.58 [7.24; 8.49], respectively. Median T-score ALMI was 2.32 [1.73; 3.08], Z-score ALMI 2.15 [1.47; 3.54]. In general, there was a decrease in the appendicular muscle mass with age. There was an inverse correlation between the age and T-score ALMI (r = -0.319, р = 0.020), as well as between the age and Z-score ALMI (r = -0.634, p = 0.000). According to the results of T-score ALMI and Z-score ALMI, there were no patients with sarcopenia. However, the calculation of the T- and Z-criteria, corrected for fat mass, has led to a significant decrease of the medians of these parameters and allowed to identify a group of patients meeting the criteria of sarcopenia (97.6%, 41/42).Conclusion:Based on ALMI, T-ALMI, and Z-ALMI, there were no patients with sarcopenia. After these criteria were corrected for fat mass, the number of such patients increased to 97.6% (41/42) and 85.7% (36/42), respectively. The potential use of the adjusted T-ALMI (FMI) and Z-ALMI (FMI) as criteria for sarcopenia and muscle mass reduction compared to the age-related normal values, as well as the classification of obesity by FMI should be studied in large epidemiological studies in different populations.
Polymorphism of the adiponutrin gene (PNPLA3) in the indigenous inhabitants of the Republic of Sakha (Yakutia) with type 2 diabetes mellitus
Authors: Kurtanov Kh. A. , Sydykova L. A. , Pavlova N. I. , Filippova N. P. , Dodokhov V. V. , Apsolikhova G. A. , Solov'eva N. A. , D'yakonova A. T. , Neustroeva L. M. , Varlamova M. A. , Borisova N. V. 
Published: August 2018

Rationale:The association of rs738409 I148M polymorphism with type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease has been confirmed for several ethnic and territorial groups. Up to now, no such studies have been performed in the populations of Yakutia.Aim:To study allele frequency distribution and to identify associations of the PNPLA3 gene polymorphism (rs738409 C>G) with T2DM in the Yakuts.Materials and methods: DNA samples from 106 T2DM patients were used in the study; the control group included samples from 72 healthy volunteers. All study participants were ethnic Yakuts and were living in the territory of the Republic of Sakha (Yakutia), Russian Federation. rs738409 polymorphism of the PNPLA3 gene was studied by polymerase chain reaction and by restriction fragment length polymorphism.Results:There were no significant difference in the distribution of the allele frequencies and genotypes of the polymorphous variant of the PNPLA3 gene (rs738409) between the T2DM patients and the healthy control. Both groups showed prevailing allele G (р = 0.01) and homozygous genotype GG (96%).Conclusion:High frequency of the allele G (74.1%) with predominance of GG genotype (58.5%) was found in type 2 diabetic patients.
Late initiation of treatment for congenital adrenal cortical hyperplasia and gender change in an adult patient
Authors: Lutsenko A. S. , Rozhinskaya L. Ya. , Kareva M. A. , Belaya Zh. E. , Maganeva I. S. 
Published: August 2018

Despite the implementation of screening programs for early diagnosis of congenital disorders, both in the Russian Federation, as well as worldwide, there are still cases of late diagnosis of congenital adrenal cortical hyperplasia (CAH), where after long-standing virilization clinicians often face the need of gender assignment, considering not only the medical indications, but also the patient's self-identification. In this article, we present a rare clinical case of patient with hypertonic type of CAH diagnosed in adulthood. At birth, the patient had ambiguous genitalia; the diagnosis of CAH was made, and the patient was assigned to female gender. However, due to some social factors, the patient was not followed up and received no treatment. The lack of treatment resulted in progression of the virilization, disturbance of the patient's gender self-identification (the female patient considered himself male), final short stature and arterial hypertension. The patient attended endocrinology clinic for the first time at the age of 19. The diagnosis of hypertensive type of CAH was based on clinical manifestation of the virile syndrome combined with hyporeninemic arterial hypertension, as well as the results of multisteroid blood analysis with identification of steroid cortisol precursors and the results of the genetic testing for CYP11B1 gene mutation. Administration of glucocorticoid replacement therapy after the late diagnosis of hypertonic type of CAH did not resolve all of the patient's concerns. The disorder of the gender self-identification in a female patient resulted in the change of the passport gender to the male one, with surgical correction in accordance to the chosen gender and replacement androgen therapy. Persistent arterial hypertension required additional anti-hypertensive treatment. This clinical case highlights that psychosocial, ethnic factors and religious factors should be taken into consideration, as well as the multidisciplinary involvement of endocrinologists, psychiatrists, andrologists and gynecologists is necessary for the management of such patients.