bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validity, reliability, and feasibility of the Brief School Needs Inventory: Evaluating educational risk for students with chronic health conditions
Authors: Elam Megan , Murphy Christel , Irwin Mary Kay 
Published: May 2019

AbstractObjectiveResearchers have increasingly emphasized the need to include routine educational and cognitive screening in the care plan for youth with chronic health conditions. Prior to now, a screener did not exist to asses risk/need in education in the pediatric setting; thus, this research aimed to examine the validity, reliability, and feasibility of the newly developed Brief School Needs Inventory (BSNI), which stratifies a patients level of educational risk/need in the context of a health condition.MethodsThe authors developed and pilot‐tested two versions of an education risk screener utilizing a mixed‐methods design, which included an expert panel review process and assessments for validity, reliability, and feasibility.ResultsNinety‐eight school‐age survivors of an oncologic disease were assessed for educational risk. Participants were assigned to two groups and administered either the initial (n = 48) or revised (n = 50) version of the screener. The final version of the screener, the BSNI, predicted educational risk in congruence with school liaisons perceived risk assessment with 94% accuracy. Liaisons also reported confidence in the results of 98% of cases for the BSNI. Similarly, expert panel results for the BSNI indicated a high degree of interrater agreement and content validity.ConclusionsThe BSNI was found to be a valid and reliable screener for predicting educational risk for youth with oncologic conditions; future studies will examine use of the screener within other pediatric chronic populations.
U.S. presidential cycles and the foreign exchange market
Authors: Ashour Samar , Rakowski David A. , Sarkar Salil K. 
Published: May 2019

AbstractWe examine the association between the foreign exchange rate of the US dollar and US presidential cycles. Results show that Republican presidencies tend to start with a strong dollar, which then depreciates over the course of the presidency. In contrast, Democratic presidencies tend to begin with a weak dollar that then appreciates. These patterns result in an apparent presidential effect in US foreign exchange rates, the direction of which depends on whether exchange rates are measured by levels or by returns.
Anterior Cruciate Ligament Reconstruction in a Rabbit Model Using a Decellularized Allogenic Semitendinous Tendon Combined with Autologous Bone Marrow-Derived Mesenchymal Stem Cells
Authors: Lu Wei , Xu Jian , Dong Shikui , Xie Guoming , Yang Shuanghui , Huangfu Xiaoqiao , Li Xiaoxi , Zhang Yang , Shen Peng , Yan Zhaowen , Liu Haifeng , Deng Zhenhan , Zhao Jinzhong 
Published: May 2019

Abstract
As a regular adoptable material for anterior cruciate ligament (ACL) reconstruction, free tendon allograft exhibits unsatisfactory outcomes, such as retarded ligamentization and tendon–bone integration. The application of bone marrow-derived mesenchymal stem cells (BMSCs), as well as a decellularized free tendon allograft developed by our group, was proven to be effective in improving ACL reconstruction results. This study aimed to investigate the efficacy and feasibility of decellularized allogenic semitendinous tendon (ST) combined with autologous BMSCs used as a substitute to free tendon allograft in a rabbit model. This study finally shows that the decellularized allogenic ST combined with autologous BMSCs could significantly improve ACL reconstruction results compared with allograft. Stem Cells Translational Medicine 2019;8:971–982
Rethinking Racine v Woods from a Decolonizing Perspective: Challenging the Applicability of Attachment Theory to Indigenous Families Involved with Child Protection
Authors: Choate Peter W. , Kohler Taylor , Cloete Felicia , CrazyBull Brandy , Lindstrom Desi , Tatoulis Parker 
Published: May 2019

AbstractThe 1983 case Racine v Woods is the leading child protection case from the Supreme Court of Canada, distinguishing bonding and/or attachment as a more important determinant of best interest for an Indigenous child than cultural connection. Using this case, courts are upholding the permanent placement of Indigenous children in non-Indigenous homes as opposed to placement within their culture. Racine v Woods reflected knowledge of attachment and family at that time but runs counter to current knowledge. Reconsideration of the factors to decide cross-cultural adoption is needed. The essential point is that attachment assessment draws from a dyadic relational theory and is being applied to communal family systems, such as Indigenous systems. Such a review is consistent with the calls to action of the Truth and Reconciliation Commission (TRC) as well as its predecessor, the Royal Commission on Aboriginal Peoples (RCAP), and recent Canadian Human Rights Tribunal (CHRT) decisions.
Geneva Conventions for the protection of war victims of 12 August 1949 and Additional Protocols of 8 June 1977 Ratifications, accessions and successions as at 31 December 1996
Authors: Centre for Legal Documentation, ICRC  
Published: May 2019

The names of countries given in the following list may differ from the official names of States.The dates indicated are those on which the Swiss Federal Department of Foreign Affairs received the official instrument from the State that was ratifying, acceding to or succeeding to the Conventions or Protocols or accepting the competence of the Commission provided for under Article 90 of Protocol I. They thus represent neither the date on which ratification, accession, succession or acceptance of the Commission was decided upon nor that on which the corresponding instrument was sent.
A comparison of clinical and linguistic indices of deviance in the verbal discourse of schizophrenics
Authors: Sanders Lynne M. , Adams Jane , Tager-Flusberg Helen , Shenton Martha E. , Coleman Michael 
Published: May 2019

AbstractThe goal of this study was to compare clinical and psycholinguistic approaches to the measurement of verbal behavior according to their ability to discriminate schizophrenic (n = 11) from manic-depressive (n = 11) and normal control (n = 11) subjects. Language samples were obtained during Rorschach testing and analyzed using a clinical measure, the Thought Disorder Index (TDI), and a battery of linguistic measures. Five linguistic categories were examined: productivity, repetition, dysfluency, cohesiveness, and syntactic complexity. On the clinical measure, schizophrenic subjects had high thought disorder scores. On the linguistic measures, the speech of schizophrenics differed significantly from the other two groups in productivity and in the number of clearly referenced elements, a measure of cohesion. This measure of cohesion was positively correlated with TDI scores. The findings are discussed in terms of the benefits of using more objective and quantitative measurements in research on thought disorganization in schizophrenia.
Notes on breeding sites of Pelecaniformes in Micronesia
Authors: de Korte J. , Meltofte H. 
Published: May 2019

SummaryDuring a tourist cruise with M.V. Academik Shokalski from Cairns (Australia) to Chuuk (Micronesia) between 20 March and 3 April 1996 we visited a number of seabird islands in Micronesia described by Nelson (1978). On these and other islands visited, we asked local people for further information on breeding seabirds. After the cruise H.M. visited Ant Atoll at Pohnpei.This note presents the results. Time did not allow us to undertake real counts so we provide only rough estimates of numbers of breeding pairs, in orders of magnitude.
Effect of Fluid Chemistry on the Interfacial Composition, Adhesion, and Frictional Response of Calcite Single Crystals—Implications for Injection‐Induced Seismicity
Authors: Diao Yijue , Espinosa‐Marzal Rosa M. 
Published: May 2019

AbstractWhile it has been shown that the mechanical properties and the reactivity of carbonate‐bearing rocks may be influenced by the chemical composition of the fluids, little is known about how the fluid composition affects their frictional response. Here, we have used atomic force microscopy to investigate the frictional characteristics of single calcite crystals in calcium carbonate saturated solutions and in two brines, NaCl and CaCl2, at a wide range of geologically relevant concentrations. Surface forces were measured to determine the ion‐specific composition of the confined fluid films and the adhesion between the confining surfaces. The effect of fluid chemistry on calcite's (dynamic) frictional response significantly depends on the normal stress. At low stresses, the confined fluid film lubricates the single‐asperity contact efficiently, resulting in low friction coefficients, especially in the case of NaCl solutions. When the pressure solution of calcite is triggered at sufficiently high stress, a significant reduction of the friction coefficient was observed, and in this case, CaCl2 solutions were shown to promote this frictional weakening more significantly than NaCl. This is the first experimental investigation of the ion‐specific frictional characteristics of calcite at the level of a single‐asperity contact. The presence of infiltrated fluids in carbonate faults may also play a critical role in fault dynamics. Hence, the results of this nanoscale study are extrapolated to carbonate fault friction in the presence of infiltrated fluids, and they contribute to advance our understanding of induced seismicity at geological scale.
A Stratigraphic Framework for the Preservation and Shredding of Environmental Signals
Authors: Toby Stephan C. , Duller Robert A. , De Angelis Silvio , Straub Kyle M. 
Published: May 2019

AbstractThe stratigraphic record contains unique information about past landscapes and environmental change. Whether landscapes faithfully transmit signals of environmental change to stratigraphy is unknown because autogenic processes, such as river avulsion, can obscure signals prior to long‐term stratigraphic storage. We develop a theoretical framework that predicts when a sediment flux signal will be transferred from the landscape to stratigraphy. This threshold magnitude is a function of signal duration. The magnitude is set by the maximum rate of autogenic volume change of the landscape, which decreases with increasing time window. Physical delta experiments, specifically designed to test our theory, demonstrate that only sediment supply signals with a magnitude greater than the threshold are stored in stratigraphy, supporting our theory. This framework allows us to assess the fidelity of the stratigraphic record to archive past signals of environmental change and predict the short‐ and long‐term impact of current anthropogenic forcing on landscapes.
A novel nonsense SMC1A mutation in a patient with intractable epilepsy and cardiac malformation
Authors: Chinen Yasutsugu , Nakamura Sadao , Kaneshi Takuya , Nakayashiro Mami , Yanagi Kumiko , Kaname Tadashi , Naritomi Kenji , Nakanishi Koichi 
Published: May 2019

AbstractCornelia de Lange syndrome (CdLS) is a cohesinopathy caused by genetic variations. We present a female with SMC1A-associated CdLS with a novel SMC1A truncation mutation (p. Arg499Ter), transposition of the great arteries, and periodic intractable seizures from 40 months of age. A review of the literature revealed that a seizure-free period after birth of at least 15 months is required for these patients to be able to walk, irrespective of the epileptic course.
Ecological traits of the world’s primates
Authors: Galán-Acedo Carmen , Arroyo-Rodríguez Víctor , Andresen Ellen , Arasa-Gisbert Ricard 
Published: May 2019

AbstractEcosystems largely depend, for both their functioning and their ecological integrity, on the ecological traits of the species that inhabit them. Non-human primates have a wide geographic distribution and play vital roles in ecosystem structure, function, and resilience. However, there is no comprehensive and updated compilation of information on ecological traits of all the world’s primate species to accurately assess such roles at a global scale. Here we present a database on some important ecological traits of the world’s primates (504 species), including home range size, locomotion type, diel activity, trophic guild, body mass, habitat type, current conservation status, population trend, and geographic realm. We compiled this information through a careful review of 1,216 studies published between 1941 and 2018, resulting in a comprehensive, easily accessible and user-friendly database. This database has broad applicability in primatological studies, and can potentially be used to address many research questions at all spatial scales, from local to global.
Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington’s disease treatment
Authors: Lopez-Hurtado Alejandro , Peraza Diego A. , Cercos Pilar , Lagartera Laura , Gonzalez Paz , Dopazo Xose M. , Herranz Rosario , Gonzalez Teresa , Martin-Martinez Mercedes , Mellström Britt , Naranjo Jose R. , Valenzuela Carmen , Gutierrez-Rodriguez Marta 
Published: May 2019

AbstractDREAM, a neuronal calcium sensor protein, has multiple cellular roles including the regulation of Ca2+ and protein homeostasis. We recently showed that reduced DREAM expression or blockade of DREAM activity by repaglinide is neuroprotective in Huntington’s disease (HD). Here we used structure-based drug design to guide the identification of IQM-PC330, which was more potent and had longer lasting effects than repaglinide to inhibit DREAM in cellular and in vivo HD models. We disclosed and validated an unexplored ligand binding site, showing Tyr118 and Tyr130 as critical residues for binding and modulation of DREAM activity. IQM-PC330 binding de-repressed c-fos gene expression, silenced the DREAM effect on KV4.3 channel gating and blocked the ATF6/DREAM interaction. Our results validate DREAM as a valuable target and propose more effective molecules for HD treatment.
Prostacyclin Production By Autogenous Venous Grafts In Dogs
Authors: Eldor A , Hoover E L , Pett S B , Gay W A , Alonzo D R , Weksler B B 
Published: May 2019

Arteries are capable of producing significantly larger quantities of prostacyclin than veins. Experiments were designed to compare the production of prostacyclin by venous autografts to that of normal veins and arteries, and to test the hypothesis that prostacyclin production by the vessel wall is related to blood pressure and flow. In 20 dogs a segment of jugular vein was interposed into the carotid system; a sham dissection was done on the opposite side. Six weeks later specimens of venous autograft, jugular vein and carotid artery were taken for histology and radioimmune assay of prostacyclin. “Arterialized” vein grafts showed prominent intima lined by endothelium, medial smooth muscle proliferation and fibrotic proliferation in adventitia. Spontaneous and arachidonic acid stimulated prostacyclin production was not significantly different in venous autografts and jugular veins. Significantly larger amounts of prostacyclin were synthesized by the carotid artery; table shows mean ± S.E. in ng/ml.We conclude that the histological and rheological changes in vein grafts do not affect prostacyclin production. While normal veins never develop atheroma, atherosclerosis is prevalent in venous autografts. The above may be explained in part by the impairment of one of the vascular defense mechanisms, namely the decreased prostacyclin production in venous grafts.
The Synthesis Of 111In. Tetraphenyl Porphyrine (TPP InCl.) And Its Use In Platelet Labelling
Authors: Vuillemin L , Cloutour C , Pommié M , Reiffers J , Ducassou D 
Published: May 2019

The synthesis of TPP InCl was realized using a modified method of A.D. Dunn previously reported (1979).In order to optimize the labeling conditions we performed a study of different parameters: incorporation of carrier-free Indium (InCl) into tetraphenyl porphyrine (TPPH2), kinetic of insertion, different concentrations of TPPH2 and InCl.The most reproducible yield (88%) was obtained using 8.108M.TTPH2 (50μg) and 3.25 × 1010M. InCl (50μCi) heated to reflux in acetic acid (250μl) for 20 hours. The purification was performed by a chloroform extraction followed by sterilisation. This radiochemical compound was used for in vitro labeling of human platelets.A comparative study with In-oxine exhibited a higher labeling efficiency, even in 10 ml of pure plasma medium (95% for 1.6 × 1010 cells).The optimal concentration of TTP InCl for which we observed no functional alteration by in vitro tests (aggregation with ADP or collagen, hypotonic stress) was 15μg/10ml suspension.The absolute number of platelets necessary for an acceptable labeling efficiency (40%) was 5×l07 cells.TPP InCl has a good platelet labeling efficiency in pure plasma medium and appears to be an interesting tracer. However further studies (elution from labeled cells, kinetics and distribution of labeled platelets) are necessary before introducing TPP InCl as a physiological platelet label.
Experience with Aspirin-Dipyridamole Prophylaxis in Sickle Cell Disease
Authors: Alkjaersig N , Chaplin H , Fletcher A 
Published: May 2019

Crisis in sickle cell disease (SSD) patients is associated with reproducible sequential hemostatic changes indicative of intravascular fibrin formation and marked disturbance of platelet economy. With crisis onset, plasma high molecular weight fibrin(ogen) complexes are elevated and there is a transient fall in platelets. Subsequently fibrinogen and platelet counts rise, reaching their peaks respectively one and two weeks alter onset. Three SSD patients have been followed by weekly clinical and laboratory examinations for a two year control and a two year prophylactic treatment period (aspirin 650 mg, dipyridamole 50 mg b.d.). Patient symptomatic status was classified weekly as 1 (asymptomatic) through 4 (hospitalized). Increase in fibrinogen concentration was significantly correlated with patient disease status. While on treatment, the patients were asymptomatic or mildly symptomatic for 85% of the time compared to 73% of the control time.Analysis of the clinical status data (2 × n Chi square) showed a statistically significant difference in favor of the treatment (p < 0.0l) and the time spent in hospital was significantly reduced during treatment (p < 0.02).
Detection of Circulating Platelet Aggregates in Thrombo-Embolic Disease
Authors: Scrobohaci Marie , Petrilă Teodora , Constantinescu M. , Stadler Magdolnra , Mihšilă Doina , Pop I. , Popa D. 
Published: May 2019

SummaryThe method of Wu and Hoak in determining circulating platelet aggregates in vivo was used.In different cardiac and vascular states, a low aggregation index is found: aorto-iliac occlusion(Leriche syndrome)- 38 cases(index X ± SD 0.52 ±0.05 in comparison with normal subjects 0.91± 0.05):valvular diseases - 24 cases (0.40±0.006); during extracorporeeal circulation- 14 cases(0. 5±0.021) ; thrombophlebitis-25 cases(0.84±0.065).After an antiaggregation treatment(Dipiridamol) in 12 cases of aorto - iliac ocdusion the value of the aggregation index normalised(0.84±0.065) Experimentally, lo rabbits were perfused with thrombin so ution(2 u./body weight k.);the lower values of the aggregation index(0.91±0.085 before and 0.43±0.035 after the thrombin perfusion) prove the fidelity of the method.The simplicity of the technique, the reproductibility in experimental conditions and the normalisation of the values after treatment prove the practical value in determining the circulating platelet aggregates.
Effects of PGI2 and Its More Stable Forms on the Aggregation and on the Camp Content of Human Platelets
Authors: Nemesánszky E. , Blaskó I. , Stadler I. , Sas G. , Pálos L. A. 
Published: May 2019

The authors investigated the anti-aggregating properties of some relatively stable derivatives of PGI2 concurrently determining the intracellular cAMP content of platelets. The ethyl-ester derivative of PGI2 and the complexes of PGI2-ethyl ester with β-cyclodextrine proved to be more stable than PGI2-sodium salt. Their stimulating effect on adenyl-cyclase correlated with the potent inhibitory effect on platelet aggregation as well. The enhancing effect of these compounds for the intracellular cAMP content have a prolonged duration time -lasting 300 minutes- compared with the only a few minutes’ effect of PGE1.These stable forms of PGI2 might be clinically useful as highly effective antiaggregating compounds.
Evidence of Abnormal Factor VIII Related Protein in Diabetes Mellitus
Authors: Cacciola E. , Giustolisi R. , Lombardo T. , Musso R. , Russo M. , Sortino G. 
Published: May 2019

Biochemical and functional properties of Factor VIII related protein (VIII:RP) have been studied in the plasma from two groups of diabetic patients with or without vascular complications compared to normal subjects.The Factor VIII related antigen (VIIIR:AG) was performed by Laurell’s electroimmunoassay (LA) and electrophoretic mobility (EM) by two dimensional crossed immunoelectrophoresis (2 DCIE). Biophysical properties were evaluated by cryoprecipitation and concanavalin A (Con A) treatment at different concentrations. Biological functions were determined using the ristocetin cofactor (RiCoF) assay on fixed-washed platelets and procoagulant activity (FVIII : C).In diabetic patients, particularly in the ones at higher thrombogenic risk, the evaluation of VI I I :C/VIII R:AG and VIIl:vWF/VI I I R:AG ratios showed a significant(P<0.00Decreased VIII R:AG with a higher co-ristocetin activity than the procoagulant one. Furthermore, biophysical and bio chemical modifications of diabetic Factor VII IR:AG, mainly a lower EM on 2 DC I E, were found. These results suggest that the Factor VI I IR:AG abnormality, detectable in diabetic plasma, can be related with an abnormal glycoprotein biosynthesis.
Changes Induced Bt Venous Stasis on Factor VIII Activities (VIII:C; VIIIR:AG; VIIIR:WF) in Different Clinical Conditions
Authors: Ponari O. , Pini M. , Manotti C. , Dettori A. G. 
Published: May 2019

F.VIII related activities (coagulant-VIII:C, antigen-VIIIR:AG, v.Willebrand factor- VIIIR.WF) before and after venous occlusion (VO) were investigated in pregnant women, in women on the pill, and in men with atherosclerosis obliterans. Mean basal values of atherosclerotic patients were not different from healthy male controls. A concordant rise in all the three activities was seen after VO in both groups without any change in the ratios between them. Basal values of women on long-term hormonal contraception were also comparable with those of a control group, while a group of third trimester pregnant women showed high values for all components, and very high ones for VIII R:AG, with striking increases in AG/C and AG/wF ratios. Following VO, strictly concordant variations in the three activities were observed in all cases, so that ratios remained always unchanged, at their different levels.The results are consistent with the hypothesis of a “complete” F.VIII released activity, induced by venous stasis in these conditions. Pregnancy has quite different effects on F.VIII in comparison with estro-progestinic treatment. No variations seem to be associate with occlusive arterial disease.