bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis
Authors: Meyer zu Schwabedissen Albrecht , Vergarajauregui Silvia , Bertog Marko , Amann Kerstin , Engel Felix B. , Daniel Christoph 
Published: December 2024

Aims
Activation of Protease Activated Receptor 2 (PAR2) has been shown to be involved in regulation of injury-related processes including inflammation, fibrosis and hypertrophy. In this study we will investigate the role of PAR2 in cardiac injury in a mouse model of hypertension using continuous infusion with angiotensin II.

Methods
Hypertension was induced in 12 weeks old wildtype (wt, n = 8) and PAR2 deficient mice (n = 9) by continuous infusion with angiotensin II for 4 weeks using osmotic minipumps. At the end, hearts were collected for analysis of left ventricular hypertrophy (LVH), myocardial capillary supply, fibrosis and localization of PAR2 expression using histological, immunohistological and mRNA expression analysis techniques. In addition, rat cardiac fibroblasts were treated with angiotensin II and PAR2 was inhibited by a blocking antibody and the PAR2 inhibitor AZ3451.

Results
Cardiac PAR2 mRNA expression was downregulated by 40±20% in wt mice treated with AngII compared to untreated controls. Four weeks after AngII treatment, LVH was significantly increased in AngII-treated wt mice compared to similarly treated PAR2-deficient animals as determined by relative heart weight, left ventricular cross-sectional area, and analysis of ventricular lumen area determined on sections. Treatment of wt mice resulted in an approximately 3-fold increase in cardiac expression of FGF23, which was 50% lower in PAR2-deficient animals compared to wt animals and therefore no longer significantly different from expression levels in untreated control mice. In contrast, cardiac interstitial fibrosis was significantly higher in PAR2-deficient mice compared to similar treated wt controls, as assessed by Sirius Red staining (>3-fold) and collagen IV staining (>2-fold). Additional experiments with isolated cardiac fibroblasts showed induction of pro-fibrotic genes when treated with PAR2 inhibitors.

Conclusion
In angiotensin II-induced cardiac injury, PAR2 deficiency has an ambivalent effect, enhancing fibrosis on the one hand, but reducing LVH on the other.
Patient reported experiences and readmissions for people with diabetes-related foot disease admitted to public hospitals, New South Wales, Australia, 2019–2022
Authors: Burnett Alexander C. R. , Williamson Jennifer , Roberts Aedan G. K. , Marashi-Pour Sadaf , Hay Liz 
Published: December 2024

Objective
Patient reported measures of hospital care are known predictors of readmission, even after accounting for risk related to age and comorbidities. This study aimed to determine the association between patient experience of diabetes-related foot disease (DFD) hospital care and unplanned hospital readmission, with a primary focus on DFD-related readmissions and a secondary focus on all-cause readmissions.

Methods
A retrospective longitudinal cohort study was conducted by linking NSW Adult Admitted Patient Survey data with administrative hospital data for persons hospitalised with DFD identified through diagnostic and/or procedure codes. Univariable and multivariable shared-frailty Cox regression models were used to examine the association between key aspects of patient experiences and 90-days unplanned hospital readmission over the period 2019–2022.

Results
Overall, 3,173 DFD patients were included. Ninety-day readmission rates for respondents with DFD were 9% for DFD-related readmissions and 16% for all-cause readmissions. Adults with DFD who could not understand explanations offered by health professionals were at increased risk of DFD-related readmission compared to those who could always understand (Hazard ratio (HR) 2.43, CI: 1.47–4.00), as well as patients who did not feel well enough to leave hospital at discharge (HR 1.93, CI: 1.41–2.64) or reported the care received was not well organised (HR 2.24, 1.45–3.47). Patients reporting that they did not receive enough information regarding their condition, treatment, or how to manage care at home were found to have a DFD-related readmission risk that was 1.5 to 1.8-times greater than those who did. Similar patterns were observed for all-cause readmissions, albeit with generally smaller effect sizes.

Conclusions
The findings highlight that elements of care related to communication, coordination, and involvement in decision making may influence unplanned readmission rates for patients with chronic conditions, such as DFD. The impact appears to be more pronounced for DFD-related readmissions compared to all-cause readmissions.
Staging a Comeback: Broadway, Hollywood, and the Disney Renaissance, Peter C. Kunze (2023)
Authors: Elfenbein Matthew Ari 
Published: December 2024

Review of: Staging a Comeback: Broadway, Hollywood, and the Disney Renaissance, Peter C. Kunze (2023)
New Brunswick, NJ: Rutgers University Press, 223 pp.,
ISBN 978-1-97882-782-0, h/bk, $150.00
ISBN 978-1-97882-781-3, p/bk, $32.95
ISBN 978-1-97882-783-7, e-book, $32.95
PENGEMBANGAN UMKM ASEP TEMPE MELALUI TEKNOLOGI DIGITAL DAN STRATEGI INOVASI DI DESA REMBUN PEKALONGAN
Authors: Tiani Riris , Falah Fajrul , Cahyani Fitri Dwi , Puspita Yuhana 
Published: December 2024

ABSTRAKTeknologi digital dan inovasi dalam suatu produk makanan memiliki peranan penting dalam sarana promosi Usaha Mikro, Kecil, dan Menengah (UMKM). Salah satu UMKM yang berpotensi ada di Desa Rembun Kecamatan Siwalan Kabupaten Pekalongan adalah Asep Tempe. Asep Tempe ini sebagai mitra dalam program pengabdian kepada masyarakat. Tujuan pengabdian kepada masyarakat ini adalah pengembangan UMKM Asep Tempe melalui bahasa sebagai branding dan pemanfaatan teknologi digital. Metode dan tahapan yang dilakukan dalam pelaksanaan pengabdian kepada masyarakat ini adalah studi pustaka, survei, dan wawancara. Luaran yang dihasilkan dalam kegiatan ini antara lain profil usaha mitra, pengembangan usaha mitra, strategi inovasi yang telah dilakukan mitra dan proses pembuatan tempe. Hasil pelaksanaan pengabdian memuat produk dan pemasaran mitra dikenal lebih luas oleh masyarakat Desa Rembun itu sendiri maupun lingkup Kecamatan, Kabupaten, bahkan Provinsi Jawa Tengah.Kata Kunci: Pengembangan, Teknologi Digital, UMKM, Tempe, Rembun ABSTRACTDigital technology and innovation in food products plays an important role in the promotion of Micro, Small, and Medium Enterprises (MSMEs). One of the potential MSMEs in Rembun Village, Siwalan District, Pekalongan Regency is Asep Tempe. Asep Tempe is a partner in the community service program. The purpose of this community service is the development of Asep Tempe MSMEs through language as branding and the use of digital technology. The methods and stages carried out in the implementation of this community service are literature studies, surveys, and interviews. The outputs produced in this activity include partner business profiles, partner business development, innovation strategies that have been carried out by partners and the process of making tempeh. The results of the implementation of community service include partner products and marketing being known more widely by the Rembun Village community itself as well as the scope of the District, Regency, and even Central Java Province.Keywords: Development, Digital Technology, MSMEs, Tempeh, Rembun
INOVASI PROMOSI DIGITAL DAN PERAN BAHASA DALAM MENCIPTAKAN DESA KREATIF: STUDI KASUS DI BLACANAN, KABUPATEN PEKALONGAN
Authors: Falah Fajrul , Tiani Riris , Priambudi Bagus Nuari , Pramesti Amanda Rafaelya , Sintana Zaila Siti 
Published: December 2024

ABSTRAKDesa Blacanan merupakan salah satu desa di pesisir Kabupaten Pekalongan yang mengalami pertumbuhan dalam bidang Usaha Mikro Kecil Menengah (UMKM). Keberadaan beberapa UMKM seperti “DNA Crabs” dan “Nafri Fashion” yang menjadi mitra pengabdian kali ini menjadi bukti besarnya potensi usaha di Desa Blacanan. Potensi yang dimiliki pada “DNA Crabs” dan “Nafri Fashion” di Desa Blacanan ini dapat dikembangkan lagi agar Usaha Mikro Kecil Menengah tersebut dapat menjangkau pasar yang lebih luas lagi. Tujuan Pengabdian kepada Masyarakat ini yaitu menciptakan desa kreatif melalui inovasi promosi digital dan peran bahasa. Metode yang digunakan serta tahapan yang dilaksanakan antara lain menggunakan survei serta observasi lapangan, wawancara mitra secara mendalam dengan beberapa pertanyaan sebagai media perantara untuk menggali informasi dari mitra, serta melakukan studi pustaka melalui beberapa jurnal terdahulu. Hasil pengabdian pada masyarakat ini menghasilkan luaran berupa artikel jurnal dan website layanan bahasa. Kegiatan pengabdian pada masyarakat ini membutuhkan tindak lanjut sebagai jawaban untuk perkembangan UMKM berbasis digital khususnya di Desa Blacanan.Kata kunci: UMKM, Promosi Digital, DNA Crabs, Nafri Fashion, Blacanan ABSTRACTBlacanan Village is one of the villages on the coast of Pekalongan Regency that is experiencing growth in the field of Micro, Small and Medium Enterprises (MSMEs). The existence of several MSMEs such as “DNA Crabs” and “Nafri Fashion” which are the partners of this service is proof of the great business potential in Blacanan Village. The potential possessed by “DNA Crabs” and “Nafri Fashion” in Blacanan Village can be developed further so that these Micro, Small and Medium Enterprises can reach a wider market. The purpose of this Community Service is to create a creative village through digital promotion innovation and the role of language. The methods used and the stages carried out include using surveys and field observations, in-depth partner interviews with several questions as an intermediary medium to extract information from partners, and conducting literature studies through several previous journals. The results of this community service produce outputs in the form of journal articles and language service websites. This community service activity requires follow-up as an answer to the development of digital-based MSMEs, especially in Blacanan Village.Keywords: UMKM, Digital Promotion, DNA Crabs, Nafri Fashion, and Blacanan
SOSIALISASI EPIGRAFI MELALUI WEBINAR
Authors: Maziyah Siti , Indrahti Sri , Alamsyah Alamsyah , Putri Atika Kurnia 
Published: December 2024

ABSTRAKPengabdian Kepada Masyarakat ini berjudul “Sosialisasi Epigrafi Melalui Kegiatan Webinar”. Adapun tujuannya adalah untuk memberikan pemahaman kepada masyarakat terkait salah satu bidang kajian dalam ilmu arkeologi, yaitu epigrafi, dan bagaimana pemanfaatannya untuk masyarakat. Pekerjaan ini dimulai dengan koordinasi dengan pihak yang terlibat dalam kegiatan, yaitu koordinasi dengan PAEI sebagai mitra dalam kegiatan ini, kemudian menentukan pembicara webinar, waktu, serta lokasi kegiatan. Adapun materi yang diterima oleh para peserta webinar adalah tentang jejak-jejak tertulis di Kabupaten Semarang serta teknik pemajangan prasasti di museum. Diharapkan kegiatan ini mampu memberikan wawasan kepada masyarakat terkait dengan pemahaman dan pemanfaatan epigrafi.Kata kunci: sosialisasi, epigrafi, webinar, hybrid ABSTRACTThis Community Service is entitled "Epigraphy Socialization Through Webinar Activities". The aim is to provide an understanding to the public regarding one of the fields of study in archeology, namely epigraphy, and how to utilize it for the community. This work begins with coordination with the parties involved in the activity, namely coordination with PAEI as a partner in this activity, then determining the webinar speakers, time, and location of the activity. The material received by the webinar participants is about written traces in Semarang Regency and the technique of displaying inscriptions in museums. It is hoped that this activity will be able to provide insight to the community regarding the understanding and utilization of epigraphy.Keywords: socialization, epigraphy, webinar, hybrid
PEMANFAATAN BAHASA IKLAN DAN DIGITAL MARKETING BAGI UMKM DI DESA BLACANAN KECAMATAN WELAHAN KABUPATEN PEKALONGAN
Authors: Suharyo Suharyo 
Published: December 2024

ABSTRAKPada era kecanggihan teknologi seperti sekarang ini semua bidang kehidupan, termasuk bidang bisnis termasuk UMKM menjadi sebuah keharusan untuk memanfaakannya jika tidak ingin usahanya tergilas oleh competitor. Salah satu UMKM mitra dalam kegiatan PKM yang penulis amati adalah UMKM jual beli kepiting “DNA CRAB: KANCA NGOBOR SELAWASE” yang ada di Desa Blacanan, Kecamatan Siwalan, Kabupaten Pekalongan. UMKM mitra ini bekerja sama dengan PKM dari Undip membuat promosi dengan memanfaatkan bahasa yang menarik . Untuk mencapai hal itu, metode yang dilakukan adalah (a) melakukan survei lokasi untuk memperoleh gambaran usaha yang dilakukan oleh Dwi Suryanto (owner), (b) mengidentifikasi kebutuhan misalnya pembuatan platform, (c) Tim PKM membuat draft promo produk/barang dagangan UMKM mitra, (d) draft tersebut lalu di-sharing-kan dengan owner UMKM mitra, dan € setelah mencapai kesepakatan baru membuat konten di IG dan facebook. Hasilnya, usaha yang dijalankan Dwi Suryanto mengalami peningkatan baik jumlah pesanan maupun jangkauan wilayah pemasaran dan branding yang semakin baik. Jadi, pemanfaatan bahasa dan digital marketing dipandang efektif sebagai “senjata” promosi barang dan jasa.Kata kunci: pemanfaatan Bahasa, digital marketing, UMKM ABSTRACTIn the current era of technological sophistication, it is imperative for all fields of life, including the business sector and MSMEs, to leverage technology to maintain competitiveness. One of the partner MSMEs engaged in PKM activities that the author has observed is the crab buying and selling MSME "DNA CRAB: KANCA NGOBOR SELAWASE" in Blacanan Village, Siwalan District, Pekalongan Regency. In collaboration with PKM from Undip, this partner MSME employs the use of engaging language in its promotional activities. To achieve this, the following method was employed: (a) a location survey was conducted to obtain an overview of the business carried out by Dwi Suryanto (owner), (b) needs were identified, including the creation of a platform, (c) the PKM team drafted a promotional plan for the products/merchandise of the partner MSMEs, (d) the draft was then shared with the owner of the partner MSME, and after reaching an agreement, content was created on IG and Facebook. Consequently, the enterprise managed by Dwi Suryanto has witnessed an uptick in both the volume of orders and the scope of its marketing reach, along with enhanced brand visibility. Therefore, the deployment of language and digital marketing strategies is regarded as an efficacious instrument for the promotion of goods and services.Keywords: language utilization, digital marketing, MSMEs
Lipschitz extension theorems with explicit constants
Authors: Basso Giuliano 
Published: December 2024

Abstract
In this mostly expository article, we give streamlined proofs of several well-known Lipschitz extension theorems. We pay special attention to obtaining statements with explicit expressions for the extension constants. One of our main results is an explicit version of a very general Lipschitz extension theorem of Lang and Schlichenmaier. A special case of the theorem reads as follows. We prove that if

X

X

is a metric space and

A
⊂
X

A\subset X

satisfies the condition

Nagata

(

n
,
c

)

\hspace{0.1em}\text{Nagata}\hspace{0.1em}\left(n,c)

, then any 1-Lipschitz map

f
:
A
→
Y

f:A\to Y

to a Banach space

Y

Y

admits a Lipschitz extension

F
:
X
→
Y

F:X\to Y

whose Lipschitz constant is at most

1,000

⋅

(

c
+
1

)

⋅

log

2

(

n
+
2

)

\hspace{0.1em}\text{1,000}\hspace{0.1em}\cdot \left(c+1)\cdot {\log }_{2}\left(n+2)

. By specifying to doubling metric spaces, this recovers an extension result of Lee and Naor. We also revisit another theorem of Lee and Naor by showing that if

A
⊂
X

A\subset X

consists of

n

n

points, then Lipschitz extensions as above exist with a Lipschitz constant of at most

600
⋅
log
n
⋅

(

log
log
n

)

−
1

600\cdot \log n\cdot {\left(\log \log n)}^{-1}

.
Christian Practical Theology and Islam: Disciplinary Intersections and Opportunities for Growth
Authors: Reda Nevin 
Published: December 2024

Abstract
This article provides a brief overview of Christian practical theology and the main Islamic theological disciplines: Sharia, kalām and Sufism. It illustrates some of the intersections of the Christian and Islamic disciplines, but also the profound differences in the conceptualization and classification of practical religious knowledge. It argues that, for Muslims, practical theology provides avenues for developing the emerging specialization of Islamic spiritual care and counselling among other things. For Christians, the article highlights Sufism and Sharia that may provide useful insights into the lived experience of spirituality and case-based ethical or moral reasoning.
Silozi verbal tonology
Authors: Bickmore Lee 
Published: December 2024

Abstract
Silozi is one of Zambia’s seven national languages, and is also spoken in parts of Botswana, Namibia, and Zimbabwe. At its heart the language can fairly be characterized as a “Shift and Double” one, where an underlying High tone shifts to the following TBU and then doubles onto the next one in defined prosodic domains. Both infinitival forms as well as a range of finite forms in various TAMs are examined. The Obligatory Contour Principle (OCP) plays an interesting role in that while it motivates various processes of High tone deletion, it only rarely constrains the core processes of Tone Shift and Tone Doubling. Some of the High tone deletions are general while others only apply in specific TAMs. As in most Bantu tone languages, Silozi exhibits Melodic High tones which help express certain inflectional properties of the verb. They have two possible landing sites – the penult or the ultima. Once linked, they precipitate the deletion of various lexical High tones on the Subject Marker, Object Marker, or verb root. In all, eleven different tonal rules are described and analyzed.
História e memória ou abandono e esquecimento?
Authors: Alves Claudia , Kozlowsky Cristiane 
Published: December 2024

O presente trabalho tem como propósito discutir a importância dos arquivos escolares tanto para a pesquisa em História da Educação quanto para o ensino na educação básica. A história da Escola Normal de Niterói e a construção do seu prédio insere-se no contexto de transformações do território urbano, no início do século XX. Compreendido como importante patrimônio que integra o conjunto arquitetônico da Praça da República, em Niterói, o prédio abriga um importante patrimônio documental. A documentação referente ao funcionamento da antiga Escola Normal, composta por fontes consideradas raras, encontra-se atualmente sob a guarda do Liceu Nilo Peçanha. O patrimônio documental não tem valor mercadológico, contudo abarca inestimável valor para a memória e para história da educação no Brasil. No contexto atual de crise do capitalismo, a educação consolidada na forma escolar sofre ataques, tanto por objetivos ideológicos, quanto econômicos. Sua memória é arrastada para a destruição.
Sustentabilidade Territorial, Crise Global e Patrimônio
Authors: Piñon De Oliveira Márcio , Costa Alves De Oliveira Claudia Maria , Ciccolella Pablo 
Published: December 2024

O presente dossiê tem como tema Sustentabilidade Territorial, Crise Global e Patrimônio. A proposição, tão cara à agenda de debates na atualidade, foi tema do VII Encontro Internacional da RIGPAC – RED INTERNACIONAL DE PENSAMIENTO CRÍTICO SOBRE GLOBALIZACIÓN Y PATRIMONIO CONSTRUIDO –, que se realizou em Arequipa, no Peru, de 06 a 08 de setembro de 2023. Inspirado na referida temática, partimos do pressuposto de que estamos vivendo no planeta uma crise generalizada e multidimensional, sem precedentes, caracterizada pela banalização da forma mercadoria, que não só afeta o que somos como indivíduos, como espécie e como sociedade, como também impacta fortemente as relações que estabelecemos com o mundo e, através dele, com o Estado, com a sociedade, com o “outro”, assim como com a natureza e com os lugares e seus patrimônios, para além do tempo presente.
Decolonialidade e Educação nos museus do IBRAM
Authors: Passos Karlla Kamylla 
Published: December 2024

O objetivo do presente artigo é refletir sobre museus e práticas decoloniais a partir da educação. Para isso foi feito um recorte das instituições geridas pelo Instituto Brasileiro de Museus (IBRAM). Usarei referências que estudaram os educativos de alguns desses espaços e respostas das educadoras/es do Ibram a um questionário nacional (Anônimo, 2023)[1]. A partir das ponderações realizadas ao longo do texto, veremos uma intenção de reflexo nos museus brasileiros como um todo (Castro, 2013). Também uso outras referências para refletir sobre decolonizar os museus como Ballestrin (2013) e Vergès (2023). Identifiquei precariedade nos educativos dos museus do Instituto, ainda que suas equipes se esforcem para construir relações mais atualizadas com os públicos. Encerro o resumo convidando você a ler e refletir se a decolonização do museu ocidental é possível.
[1] O artigo é fruto de um recorte dos dados apresentados em uma tese defendida em 2023.
Юридический состав сделок в трудовом праве
Authors: Luzyanin Taras 
Published: December 2024

В современной доктрине проблемам сделок в трудовом праве посвящено немного работ. Действующее законодательство и судебная практика все чаще используют понятие «недействительный трудовой договор» и даже допускают применение к нему нормативных положений о гражданско-правовых сделках. Отталкиваясь от общетеоретического учения о юридических фактах, автор изучает теорию сделок в трудовом праве через призму понятия «юридический состав», в качестве элементов которого выделены объективные (содержание и форма сделок) и субъективные (субъекты сделок в трудовом праве и их воля). В содержании сделок выделены условия, которые позволяют произвести их оценку для нужд теории и практики, — квалифицирующие, индивидуализирующие и инициативные. Всесторонняя оценка принципов законности, фактической возможности исполнения и определенности в содержании сделки позволяет автору прийти к выводу, что в трудовом праве они имеют собственное отраслевое наполнение. Морально-этические положения ввиду явной субъективной ориентированности не рассматриваются в качестве источников, которым должны соответствовать трудовые сделки. Учение о форме характеризуется множеством источников ее регулирования, недостаточным исследованием нетрадиционных форм и правовых последствий ее несоблюдения. Под формой трудовой сделки автор понимает дозволенный способ выражения волеизъявления субъектов, а также правовой институт (в виде совокупности общих и специальных норм, устанавливающих требования к внешнему порядку фиксации данного юридически значимого акта поведения в социально-трудовой сфере). Исследованы проблемные аспекты сделкоспособности (как особой разновидности трудовой правосубъектности), выделены такие ее стороны, как общая, специальная и индивидуальная. Поскольку воля юридического лица при совершении трудовой сделки фактически выражается лицом, действующим от его имени, отмечается, что целесообразно предусмотреть последствия превышения или отсутствия полномочий должностных лиц при совершении трудовых сделок. Волевой компонент сделок выражен в системе потребностей, интересов, мотивов и целей участников сделки, которые в совокупности имеют особое значение в оценке регулирующей силы сделки.Для цитирования: Лузянин Т.Ю. Юридический состав сделок в трудовом праве // Право. Журнал Высшей школы экономики. 2022. Т. 15. № 2. C. 187–215. DOI:10.17323/2072- 8166.2022.2.187.215