bluuebunny/crossref_metadata_2025_split huggingface dataset:
A várandóssággal kapcsolatos szorongást mérő Pregnancy Related Thoughts kérdőív hazai adaptálása
Authors: Kopcsó Krisztina , Bornemisza Ágnes , Sz. Makó Hajnalka 
Published: October 2018

Abstract: Introduction: Although pregnancy related anxiety has significant, negative effects on the outcomes of mothers, birth and children, there is a lack of research in Hungary regarding its prevalence and characteristics. Aim: The aim of the present study was the adaptation of the Pregnancy Related Thoughts by Rini et al. for a Hungarian sample, including the investigation of its psychometric properties. Method: 248 pregnant women, aged 30.46 years (SD = 4.94) responded our online questionnaire, at 4–40 weeks of gestation (M = 27.9; SD = 9.52). Besides the Pregnancy Related Thoughts, relevant demographic and health questions, generalized anxiety and depression screeners, a relationship satisfaction scale and a sense of control questionnaire were applied. Results: The 9-item Hungarian version of the Pregnancy Related Thoughts proved to be a reliable and valid one-dimensional questionnaire, with the highest score among women in the first trimester. Pregnancy-specific anxiety significantly and moderately correlated with trait-anxiety, depression, external control, subjective health status and relationship satisfaction, in the expected direction. In addition, women who experienced bleeding or abdominal pain during pregnancy reported significantly higher pregnancy related anxiety than others. Conclusion: The Hungarian version of the Pregnancy Related Thoughts can be a useful instrument for mapping pregnancy anxiety in Hungary. Orv Hetil. 2018; 159(43): 1754–1760.
Inherited Bleeding Disorders in Iraq and Consanguineous Marriage
Authors: Al-Rahal Nidal Karim 
Published: October 2018

Background: Consanguineous marriage is defined as inbreeding between second cousins or closer. In such families there will be a potential increase in the autosomal recessive traits with its lethal effect, with an increased risk of morbidity and mortality in the new generation. Inherited bleeding disorders (InBDs) are rare complicated diseases, difficult and expensive to treat, the defect usually due to quantitative or qualitative deficiency of clotting factors, platelets or fibrinolysis. This study attempts to assess the diversity, the frequency and the clinical features of inherited bleeding disorders (InBDs) in central part of Iraq and to determine the state of consanguineous marriage. Materials and Methods: This is a prospective cross-sectional study conducted in the National Center of Hematology NCH, Baghdad, Iraq between June2014 and June 2017. In total, 256 pediatrics and adult patients were included. Full bleeding history, family history, drug history and consanguineous marriage were recorded and followed by medical examination. First-line laboratory tests were performed and then were followed by further tests included mixing study, lupus anticoagulant testing, clotting factor activity assay, von Willebrand Antigen (VW: Ag), Ristocetin co factor vWF: RiCoF activity and platelet function test. Results: The range of age was from 1 month to 57 years, with mean age 8.424±8.623 years and median age of 6.5years. The male to female ratio was 1.1:1. The most common age group was in the range of 1-10 years (46.45%). Family history was positive in 55.07% of patients (P >0.05). The consanguinity was found in 76.95% of the families studied (P <0.0001). The most prevalent InBD was von Willebrand disease (42.98%) with majority type 3VWD (86.4%). The second most prevalent was thrombasthenia (36.71%) and the majority had Glanzmann’s thrombosthenia (86.2%). Rare bleeding disorders (RBDs) were observed in 6.25% of patients and the most common factor deficiency was FVII. Conclusion: Consanguinity is high in patients with inherited bleeding disorders in Iraq, leading to emergence of life-threatening autosomal recessive inherited diseases. Genetic counselling is recommended besides education and awareness to minimize such rare illnesses in the community.
Advancement in Stem Cell Therapy for Ischemic Myocardial Cell: A Systematic Review
Authors: Bareeqa Syeda Beenish , Bibi Fazeela , Ahmed Syed Ijlal , Samar Syeda Sana 
Published: October 2018

Background: Cardiac muscle possesses a limited capacity to regenerate its tissue on its own. It is less likely to reverse the altered cardiac functioning to its normal physiological state after a major myocardial infarction. Stem cell transplantation provided a unique therapeutic approach in managing such injuries. There has been a substantial debate about the complexity, scope and medical application of stem cell transplantation in past few years.
Materials and Methods: An extensive review of medical literature was conducted to establish the consensus about the possible mechanism of cell renewal, associated complications and risks of failure of this technique. Twenty cases of mammalian animals and twenty-four cases of stem cell transplantation in human subjects were reviewed.
Results: Most common associated complication was re-stenosis of coronary artery. Few clinical trials reported the failure in improving cardiac functioning. The success rate of stem cell transplantation was remarkable in the literature related to experimental animal subjects.
Conclusion: It was concluded that renewal of the cardiac cell is a result of induction of angiogenesis and prolonged cell survival. This topic still requires an immense amount of research to fill the gap in adequate knowledge.

Keywords: Mesenchymal stem cells, Myocardial infarction, Cardiomyocytes, Hematopoietic stem cells
Determination of Clinical Process and Response Rate to Treatment in Patients with Gestational Trophoblastic Neoplasia (GTN) with Low and High Risk and Evaluation of Their First Pregnancy Outcome
Authors: Aznab Mozaffar , Nankali Anisodowleh , Daeichin Sara 
Published: October 2018

Background: The present study was conducted to determine the response to treatment in patients with GTN, the survival rate and to investigate the outcomes of first pregnancy after chemotherapy.
Materials and Methods: The treatment protocol was based on the FIGO Staging of GTN and the Modified WHO Prognostic Scoring.
Results: Complete remission was achieved with MTX in 100% of the low-risk patients and with combination therapy in 91% of the high-risk cases. Out of 27 low-risk patients, 21 had no metastasis 6 had lung metastasis, 18 preserved their fertility and conceived in the first year following the chemotherapy. Out of 3 patients who had developed invasive moles, 1 got pregnant after chemotherapy. Four of the patients with choriocarcinoma conceived in the first year following the chemotherapy. In the patient with placental site trophoblastic tumors, there was no pregnancy due to hysterectomy.
Conclusion: GTN was found to be a chemosensitive condition, but more effective therapeutic protocols are therefore required.
Keywords: Gestational trophoblastic neoplasia, Choriocarcinoma, High dose chemotherapy, Pregnancy
Inclusión del yogurt artesanal de leche de búfala en el pienso de gallinas ponedoras Isa Brown y su efecto en la producción y calidad del huevo
Authors: Ortiz-Milán Abel , Gómez-Sarabia Solimar , Jay-Herrera Osmany , Brea-Maura Odelin 
Published: October 2018

Con el objetivo de evaluar la inclusión de 0 (control), 5, 10 y 15 ml de yogurt artesanal/ave/día en el pienso de gallinas ponedoras Isa Brown, y su efecto en la producción y calidad del huevo, se utilizaron 240 aves durante 60 días, en el estado Delta Amacuro, Venezuela, siguiendo un diseño completamente aleatorizado, con cuatro tratamientos y seis repeticiones; cada repetición se realizó con 10 gallinas. Al final del experimento se obtuvo que la producción total de huevos (3.04, 3.22, 3.38 y 3.58 kg/ave), el índice de puesta (88.66, 90.00, 93.33 y 96.66 %), la conversión (2.37, 2.24, 2.13 y 2.01 kg alimento/kg huevo) y el peso del huevo (58.96, 60.86, 62.33 y 65.26 g) mejoraron significativamente en las aves a medida que se incrementó en el pienso la dosis de yogurt de búfala. El porciento de huevos rotos no difirió entre tratamientos, mientras que el porciento de huevos cascados y huevos sucios fue superior significativamente para 15 ml de yogurt con respecto al control. Las características sensoriales del huevo cocido (olor, sabor y textura) no mostraron cambios significativos, según el criterio de los panelistas encuestados. Se concluye que la inclusión del yogurt artesanal elaborado con leche de búfala en la dieta de gallinas ponedoras Isa Brown estimuló el índice de puesta y el tamaño del huevo, sin que se presentaran efectos significativos en la calidad sensorial del huevo.
New Surfactants and Cosolvents Increase Oil Recovery and Reduce Cost
Authors: Nadeeka Upamali Karasinghe A. , Liyanage Pathma Jith , Jang Sung Hyun , Shook Erin , Weerasooriya Upali P. , Pope Gary A. 
Published: October 2018

Summary
Scientific understanding of how the molecular structures of surfactants and cosolvents affect microemulsion properties greatly speeds up the process of arriving at optimal chemical formulations for enhanced recovery of a specific crude oil. With the main emphasis on reducing the chemical cost of the formulations, novel surfactants and cosolvents have been developed and shown to have superior performance. We have synthesized and tested surfactants with different hydrophobe sizes and structures varying from ultrashort to large to satisfy a variety of crude-oil requirements over a wide range of reservoir conditions. The cosolvents and surfactants with ultrashort hydrophobes offer advantages such as short equilibration time for the microemulsion formation and lower microemulsion viscosity. Chemical formulations developed using these chemicals have shown excellent performance with very low cosolvent and surfactant retention in cores. Low retention means less chemicals can be used to recover each barrel of oil from the reservoir. These chemicals can be made commercially at low cost. Through use of these new developments, the chemical cost per barrel of oil is low enough to be economically viable, even at low crude-oil prices.
Challenges and Value of Interference Testing During Early Production of Kashagan Field
Authors: Saurbayev Ilyas , Reedy John , Bukharbayeva Aigerim , Hatiboglu Can , Massingill Amber 
Published: October 2018

Abstract
This paper presents the use and value of information obtained from interference testing performed during the early production of Kashagan field. Numerous field examples of the interference and pulse tests are presented along with their implications for improving reservoir characterization and modeling. Design aspects of the conducted tests and an approach to address uncertainties in the pressure data are also described.
A significant amount of important interference data was captured during the start-up and subsequent ramp- up of Kashagan field. This included local well to well interference and pulse testing as well as an extended test that covered a larger area of the field. However, operational activities at observer wells complicated the available data and necessitated application of a pressure correction methodology. This methodology had to account for the inherent uncertainty in the interpretation of the data. Moreover, to increase our confidence in the interpretation, a dedicated pulse test was performed in the specific part of the field. Finally, responses from all observation wells were integrated and analyzed to capture big picture learnings from the early interference testing program.
When results of the interpreted interference response from all observers were combined, several groupings of wells became apparent. This helped to understand the degree of connectivity in various areas of the field. For dynamic model calibration, it was preferable to have a range of interference responses for each well to reflect uncertainty in the data. Therefore, so called "early" and "late" response curves were developed for each well. Overall, the collected and analyzed interference data was very useful in reducing uncertainty during this early period and will be used to optimize reservoir management decisions and future phases of the field development.
Results presented in this paper can be used by practicing engineers as another great example for advocating the use of permanent downhole gauges (PDHGs) and importance of proper planning and execution for the interference and pulse tests.
Design and Performance of Smart Water Shock Injection SWSI in Carbonate Reservoirs
Authors: Al-Kharusi Balqees , Pourafshary Peyman , Mosavat Nader , Al-Wahaibi Yahya 
Published: October 2018

Abstract
Hydrocarbon liquid production from carbonate formations should be increased in order to meet the global growing demand of fossil fuels. Conventional water flooding application in these reservoirs are not very effective mainly due to the oil-wet nature of carbonate reservoirs. Special attention has been recently directed on changing ions composition of the injected water to improve the oil recovery which is referred to smart water flooding. Different studies showed that the adjusted water altered the rock wettability to preferentially more water wet which improves the ultimate oil recovery.
A major problem in this approach is to adjust the ions composition of the huge volume of the injected brine. In this research, we introduced a novel, more practical approach as Smart Water Shock Injection (SWSI) to reduce the pore volume size of the injection. This approach is applied to an Omani carbonate field. Since smart water is injected within a short period of time, called shock, governing parameters such as brine salinity and active ions have to be optimized to achieve the highest oil recovery. Analytical methods such as contact angle measurement, pH measurement, brine analysis, SEM-EDS, and zeta potential measurement were also utilized to provide comprehensive analyses of the performance of the proposed method.
The results verified that increasing the concentration of sulfate ions and magnesium ions in the injected diluted brine turned the oil-wet carbonate surface to a water-wet surface which affects the oil production by a shock injection. The new sequence of the SWSI makes the low salinity water flooding method more practical and cheaper. Core flooding experiment showed that SWSI as the tertiary oil recovery approach improves the oil recovery by 4.3 %. Diagnostic tests showed that, carbonate dissolution and multi ion exchange (MIE) are dominant mechanisms to alter the wettability and improve the oil recovery in our approach.
Improved Methodology for LWD Response During Closed Hole Circulation Drilling
Authors: Bekkaliyev Zharas , Nursaidova Roza , Inanc Feyzi , Salimova Assel , Stefaniak Andrew 
Published: October 2018

Abstract
We document a technology for environmental corrections during logging while drilling (LWD in wash down mode) operations in closed hole circulation drilling (CHCD). The technology documents a new way to estimate hole size (caliper) and other environmental corrections through implementation of a neural net model to identify zones of varying bore hole fluids followed by new algorithms to create final products. Results with new drill wells spurred a re-evaluation of historical wells ending in a new porosity estimation methodology.
Initial quality checks of Neutron-Density cross-plot data for new wells drilled in CHCD mode indicated that applied environmental correction resulted in potential errors in porosity estimations. Investigation of static and dynamic annular pressure data suggested that mixed density annular fluids, drilling mud and sacrificial fluid, created varying logging conditions. A neural net model was developed to account for these conditions. From this analysis a set of lab test were completed and new algorithms were applied to develop a synthetic caliper.
The results of this work provided internally consistent porosity estimation methodology in zones of wells that are typically difficult to evaluate due to complex drilling conditions. The products provide a more thorough understanding of the distribution of porosity in formation and understanding of potential non-matrix features (fractures/karst). The methodology allowed for re-examination of historical wells that were deemed unusable and unsuitable for porosity estimation. Both of these insights are being considered in the history match and prediction of the reservoir model. The integrated approach of the team demonstrates the value of the technical approach by the contractor and operator to deliver results for the project.
Field Integrated Operating Center: A Collaborative Environment Enabling Daily Operational Support and Maximizing Oil Production
Authors: Svyatov Aidar , Kassenov Baurzhan , Shantayev Arman , Zhulkashev Ruslan , Yessengeldin Askar , Janabekov Berik 
Published: October 2018

Abstract
Tengizchevroil (TCO) is the largest operator in Kazakhstan developing two of the world’s deepest supergiant oilfields - Tengiz and Korolev.
The concept of an Integrated Operations Center (IOC) has been developed and implemented over the last few years in TCO. The TCO IOC approach has been established in both Plants and Field Operations to perform rigorous planning of short and long-term activities, improve communication between operational teams (Field Operations, Plant Operations, Reservoir Management Group, Process Engineering Team, Projects Team, etc.) and increase production efficiency at the Field and Plant level. Two key objectives of the IOC are to utilize an Integrated Asset Management approach to ensure field deliverability is available to maintain plant production demands throughout the year, as well as to utilize planned/unplanned facility downtime to execute field facility maintenance and project scope, reservoir surveillance jobs, etc.
The IOC collaborative environment allowed TCO to improve production efficiency in the field and at the Plant by establishing a clear communication bridge between multi-discipline groups, and implementing a "conflict resolution" process, which enabled all relevant groups to perform integrated planning. The overall IOC process has added more than 15,000 bbls of daily production.
One of the key components to the success of the Integrated Asset Management approach was to embed a production engineer in the IOC to ensure field work scope decisions and scheduling are based on short and long-term production deliverability.
This paper outlines how a real-time system can be used for production planning optimization, resource allocation and integrated plan development. The paper includes a discussion of how the Integrated Asset Management approach can be utilized in an operation center to address some of the challenges associated with production planning in field operations.
Implementation of Virtual Flow Metering Concept in Kashagan Field
Authors: Mursaliyev Adilbek 
Published: October 2018

Abstract
This paper presents the implementation and value of Virtual Flow Metering (VFM) concepts for Kashagan Field wells. The VFM models are used for real time well performance estimation. The models are expected to be used to detect fluid properties changes, restrictions in the well tubing and instrumentation malfunctioning.
The paper also describes how the virtual meters are built, tuned and maintained.
One of the VFM techniques is use of Vertical Lift Performance (VLP) equation. The equation describes the relationship between the velocity of the reservoir fluid in the well tubing and pressure drop across the tubing, fluid and tubing parameters. The method consists of testing each well at wide range of flow rates and tuning the VFM model, based on VLP equation.
The method was tested on wells equipped with individual MPFM. After tuning stage, the model was compared against real time MPFM measurements. The models are also tested by estimation of bottom-hole pressure (BHP) using physically measured flow rate as an input and comparing against measured BHP. The fluid properties and phase fractions are calculated using Peng-Robinson EOS programming routines. Wells used for testing have different deviations from vertical.
The results of tuning the VFM models and testing against real time measurements show that the method can be used for accurate well performance estimation in real time. The models are capable of estimating flow rates with an average error of ±5% of span. It is observed that better match is acquired for high flow rates and for wells with less deviation from vertical. Good results were achieved in estimation of BHP using same tuned models.
The inferred friction coefficients were also compared against friction coefficients calculated by use of Colebrook-White equation. The observation is that there is very good match between the two for certain flow range.
The implementation of VFM models was instrumental on improving the overall reconciliation factor for hydrocarbon allocation process.
As a future work, it is important to better understand the following: Impact of slippage between phases to friction loss in the well production tubing;Impact of flow pattern to friction loss;Impact of well curvature (deviation) to friction loss.
The method presented in the paper makes it possible for an engineer, involved in well performance measurements, to implement using readily available tools with no additional cost for dedicated software. This is a practical implementation of simple VLP equation based VFM model which were tested on producing wells with real time measurements.
Big Loop Technology in Modeling Paleozoic Traps of the Bolshekinelsky Fault Zone: A Case Study
Authors: Samokhina Ekaterina , Semenov Alexander 
Published: October 2018

Abstract
Construction of up-to-date reservoir models depends on the input data, the quality of the geologic, geophysical and petrophysical field data, as well as utilized technology.
In case of limited or poor geological and petrophysical data geological modeling could result in several different variants or reservoir model. When making a decision according to one of the possible variants all available data as well as regional geology and tectonic information of the region should be taken in account.
For the developing fields relevance of geological model is checked at the stage of hydrodynamic modeling when matching to history data. Work on the project in such cases consists of several iterations and implies specialized software and close collaboration between specialists. Advanced technologies have a wide range of modeling tools, which constantly evolve to ensure the speed and efficiency of their use. The Big Loop solution integrates static and dynamic model uncertainty under one streamlined workflow.