bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rehearsed Language of Psychoanalysis
Authors: Kaul Nilofer 
Published: October 2018

AbstractTaking up Bion's idea of a continuum between the psychotic and non‐psychotic parts of the mind, this paper looks at clinical moments where the primitive part – psychotic and ‘autistic‐contiguous’ – mimes language and takes over the analytic field. The patients discussed seem to intuit the analyst's blind spots and a pseudo‐language takes over as primitive parts of the patient collude with those of the analyst. The three patients discussed here use registers of speech which vary from over‐abundant to quicksilver and dried. However, it is not as much a communicative use as it is evacuative and adhesive. Verbal language offers familiar moulds in terms of unfree associations, pre‐existing narrative structures, syntax, figures of speech (symbols, metaphors, paradoxes) and common psychoanalytic tropes (dreams, primal scenes). Primitive parts of the mind nestle in these moulds rather than disturb them. It is only through examining the countertransference and abjuring collusions that the analyst may be able to contact the terrifying or enclosed parts in the field. ‘Death’, for instance, represents the limits of language and as it is unpacked, it comes to acquire a range of meanings which allow the recovery of thinking. I have tried to demonstrate the experience of verbal language as a seductive screen that analyst and analysand collaboratively create to make bearable the incomprehensibility of the encounter. In doing this what emerges is a ‘thick description’ that helped and reflects on different kinds of collusion. The paper tries to capture the experience of collusion as well as a return from it.
Ultrasound‐guided percutaneous nephrolithotomy for upper urinary tract calculi in patients with spinal deformity: a decade's experience
Authors: Wang Shu , Zhang Xin , Xiao Bo , Hu Weiguo , Chen Song , Li Jianxing 
Published: October 2018

ObjectivesTo evaluate the efficacy and safety of ultrasound (US)‐guided percutaneous nephrolithotomy (PCNL) in managing upper urinary tract calculi in patients with spinal deformity based on our experience over the last decade.Patients and MethodsA retrospective study was conducted on patients with spinal deformity who were admitted to Beijing Tsinghua Changgung Hospital and collaborative hospitals from August 2004 to August 2017. Patients diagnosed with urolithiasis and who underwent US‐guided PCNL, performed by the same surgeon, were included. Patients’ data were collected and the following variables were analysed: age; sex; plain abdominal radiograph of the kidneys, ureters and bladder (KUB); computed tomography (CT); stone burden; evaluation of spinal anatomy; respiratory function; operative time; and postoperative findings. The severity of surgical complications was determined according to the modified Clavien classification system (MCCS).ResultsA total of 72 patients (41 males and 31 females) were included, with a mean (range) age of 35 (21–69) years. The mean (range) stone diameter was 38 (19–68) mm. Seven patients had bilateral PCNL, completed in staged surgery with a 1‐week interval. Five kidneys received staged PCNL because of either large residual stones or the potential risk of a long operation time. In all, 19 patients underwent the surgery in a prone position, 29 lateral, nine oblique supine, and the other 27 in unconventional positions (lateral prone, lateral supine, and lateral jackknife position). All procedures were successfully completed with no major complications during the operation. The mean (SD) tract building time was 8.5 (1.7) min. The mean (SD) stone disintegration time was 39.3 (14.6) min. The mean (range) temperature and postoperative haemoglobin (Hb) drop on the first postoperative day were 37.6 (36.7–39.2) °C and 1.5 (0.2–4.3) g/dL, respectively. Four patients needed blood transfusions and none of the patients had septic shock or severe renal bleeding requiring angiographic renal embolisation or nephrectomy. A stone‐free status was achieved in 71 kidneys (89.87%). Eight patients with residual fragments ≥4 mm were either observed without treatment during follow‐up or re‐treated with shockwave lithotripsy (SWL) according to clinical significance.ConclusionPCNL in patients with spinal deformities is challenging but safe and effective. US‐guided puncture and access establishment has its unique advantages when such patients are placed in unconventional positions.
Twinned careers: Public sector practitioners in public administration teaching and research
Authors: O’Neill Michael A. , Wilkins John K. 
Published: October 2018

AbstractScholarship in Canadian public administration programs takes many forms. One of these is the contribution made by practitioners. Yet very little is known about this group and, with the exception of Kenneth Kernaghan's articles, there is little Canadian literature on practitioner‐scholars. Taking Kernaghan's work as a starting point, we explore the contribution of practitioner‐scholars and shed light on their background and contribution to public administration scholarship. Our study finds that practitioner‐scholars are well‐qualified and engaged public administration professionals whose contribution is much broader than that first described by Kernaghan.
Lessons from the evidence on evidence‐based policy
Authors: French Richard D. 
Published: October 2018

AbstractWhat can we learn from the evidence on evidence‐based policy (EBP)? We summarize and synthesize the themes that converge from the observations of those scholars who have studied EBP, including studies of “science and public policy” and “knowledge utilization.” Many characteristics of the policy‐making environment escape the notice of the majority of advocates of EBP; we examine them in summary. Next, we identify key lessons from research that addresses directly the practice of policy‐making. A substantial consensus on the experience of EBP in policy‐making emerges. However, when we examine the conclusions of various students of EBP as to the requirements for its successful implementation, we see that no consensus exists as to the way ahead. EBP will remain a popular ideal among scientists and social scientists because of its intuitive appeal, but would not appear to offer a simple prospect of rapid and significant improvement in the application of research to public policy.
Immunosuppressive therapy of autoimmune hypoparathyroidism in a patient with activating autoantibodies against the calcium‐sensing receptor
Authors: Chamberlin Mina , Kemp E. Helen , Weetman Anthony P. , Khadka Bhupesh , Brown Edward M. 
Published: October 2018

SummaryContextActivating antibodies directed at the extracellular calcium‐sensing receptor (CaSR) have been described in autoimmune hypoparathyroidism in the setting of isolated hypoparathyroidism or autoimmune polyglandular syndrome type 1.Materials and MethodsA 34‐year‐old female presented with hypocalcaemia (6.0 mg/dL) and hypomagnesaemia (1.1 mg/dL) accompanied by low serum PTH (2.4 pg/mL) as well as urinary calcium and magnesium wasting. She was diagnosed with hypoparathyroidism, which was refractory to standard therapy. She was started on 60 mg prednisone and 150 mg azathioprine treatment daily on suspicion of an autoimmune aetiology. The patient was tested for CaSR antibodies.ResultsThe patient was positive for CaSR antibodies of the IgG1 subtype, which stimulated phosphorylation of extracellular signal‐regulated kinases 1 and 2 (ERK1/2) and inositol phosphate (IP) accumulation. Post‐treatment with prednisone and azathioprine, her serum calcium and magnesium normalized, as did her CaSR antibody titre and antibody‐mediated stimulation of ERK1/2 phosphorylation and IP accumulation.ConclusionThis is the first demonstration of CaSR antibody‐mediated hypoparathyroidism responsive to immunosuppressive therapy, adding to the evidence that autoimmune hypoparathyroidism can be, in some cases, reversible and not the result of autoimmune parathyroid destruction.
Factors influencing medical student self‐competence to provide weight management services
Authors: Doshi R. S. , Gudzune K. A. , Dyrbye L. N. , Dovidio J. F. , Burke S. E. , White R. O. , Perry S. , Yeazel M. , van Ryn M. , Phelan S. M. 
Published: October 2018

SummaryThis study aimed to identify factors associated with high obesity care self‐competence among US medical students. The authors performed a cross‐sectional analysis of 2014 survey data on fourth year medical students collected online as part of the Medical Student Cognitive Habits and Growth Evaluation Study (CHANGES). Independent variables included quality and quantity of interaction with patients and peers with obesity; hours of communication and partnership skills training; negative remarks against patients with obesity by supervising physicians, and witnessed discrimination against patients with obesity. The dependent variable was self‐competence in providing obesity care. Of 5823 students invited to participate, 3689 (63%) responded and were included in our analyses. Most students were white (65%), half were women and 42% had high self‐competence in caring for patients with obesity. Factors associated with high self‐competence included increased interaction with peers with obesity (39% vs. 49%, P < 0.001) and increased partnership skills training (32% vs. 61%, P < 0.001). Increased partnership skills training and quantity of interactions with peers with obesity were associated with high student self‐competence in providing obesity‐related care to patients. Medical schools might consider increasing partnership skills training to improve students’ preparedness and skill in performing obesity‐related care.
Where Should I Focus My Return Reduction Efforts? Empirical Guidance for Retailers
Authors: Shang Guangzhi , Ferguson Mark E. , Galbreth Michael R. 
Published: October 2018

ABSTRACTOwing to the generous refund policy ubiquitous among today's retailers, returns are prevalent and expensive to manage. Implementing buyer assistance programs and adjusting return time windows are two common methods that retailers use to actively influence return rates. A buyer assistance program can improve consumer understanding and reduce returns, but to be effective it must be focused on the products that are most likely to be returned. Managing return rates by adjusting return time windows, on the other hand, requires an understanding of the time dimension of returns, a topic for which there is scant guidance in the literature. Using a large dataset of consumer electronics purchases and returns for a major U.S. retailer, our study contributes to the research and practice of retail operations by: (i) providing new insights into the drivers of product returns and (ii) analyzing the time length of consumers' product trial, which can inform return time window decisions. We show that both product maturity (where a product stands in its life‐cycle) and variety (the number of competing alternatives) are negatively associated with the probability of a return. By separating pure returns and exchanges, we further demonstrate that while more variety considerably reduces the former, it only marginally increases the latter. In addition, we find that consumers with more past returns not only have a higher probability of future returns but also tend to make late returns, with both factors increasing a retailer's cost to serve them. Finally, our analysis of the time to return shows that retailers may benefit from customizing their return time windows across different product categories, as well as enlarging the window during holidays.
The relationship between remittances and macroeconomic variables in times of political and social upheaval: Evidence from Tunisia's Arab Spring
Authors: Bouoiyour Jamal , Selmi Refk , Miftah Amal 
Published: October 2018

AbstractIf Tunisia is hailed as a success story with its high rankings on economic, educational, and other indicators relative to other Arab countries, the popular 2011 uprisings underscored the fragility of its main economic pillars, including those of tourism and foreign direct investment. This paper examines the economic impact of migrants’ remittances, which are expected to exhibit relatively countercyclical behaviour during periods of intense upheaval. This study is novel in its methodological approach, which is used to pinpoint the dynamic effects of remittances on key macroeconomic variables within an unstable framework. The analysis reveals that the effect of remittances on Tunisia's economy has varied over time. Prior to the Arab Spring, remittances had a short‐term negative influence on economic growth, varying effects on domestic investment and positive impacts on consumption. In considering the post‐Arab uprisings, positive and strong impacts of remittances on growth and consumption are found in the long run while negative and moderate investment effects of remittances are shown over the short and medium term.
Metabolic and cardiovascular consequences of shift work: The role of circadian disruption and sleep disturbances
Authors: Kervezee Laura , Kosmadopoulos Anastasi , Boivin Diane B. 
Published: October 2018

AbstractShift work, defined as work occurring outside typical daytime working hours, is associated with an increased risk of various non‐communicable diseases, including diabetes and cardiovascular disease. Disruption of the internal circadian timing system and concomitant sleep disturbances is thought to play a critical role in the development of these health problems. Indeed, controlled laboratory studies have shown that short‐term circadian misalignment and sleep restriction independently impair physiological processes, including insulin sensitivity, energy expenditure, immune function, blood pressure and cardiac modulation by the autonomous nervous system. If allowed to persist, these acute effects may lead to the development of cardiometabolic diseases in the long term. Here, we discuss the evidence for the contributions of circadian disruption and associated sleep disturbances to the risk of metabolic and cardiovascular health problems in shift workers. Improving the understanding of the physiological mechanisms affected by circadian misalignment and sleep disturbance will contribute to the development and implementation of strategies that prevent or mitigate the cardiometabolic impact of shift work.
Peri‐lead edema after deep brain stimulation surgery for Parkinson's disease: a prospective magnetic resonance imaging study
Authors: Borellini L. , Ardolino G. , Carrabba G. , Locatelli M. , Rampini P. , Sbaraini S. , Scola E. , Avignone S. , Triulzi F. , Barbieri S. , Cogiamanian F. 
Published: October 2018

Background and purposeThe aim of this study was to define the prevalence and characteristics of peri‐electrode edema in a prospective cohort of patients undergoing deep brain stimulation (DBS) surgery and to correlate it with clinical findings.MethodsWe performed brain magnetic resonance imaging (MRI) between 7 and 20 days after surgery in 19 consecutive patients undergoing DBS surgery for Parkinson's disease. The T2‐weighted hyperintensity surrounding DBS leads was characterized and quantified. Any evidence of bleeding around the leads was also evaluated. Clinical and follow‐up data were recorded. In a subgroup of patients, a follow‐up MRI was performed 3–6 weeks after surgery. We also retrospectively reviewed the post‐operative computed tomography scans of patients who underwent DBS at our center since 2013.ResultsMagnetic resonance imaging showed a peri‐lead edematous reaction in all (100%) patients, which was unilateral in three patients (15.8%). In six patients (31.6%), we detected minor peri‐lead hemorrhage. Edema completely resolved in eight out of 11 patients with a follow‐up MRI and was markedly reduced in the others. Most patients were asymptomatic but six (31.6%) manifested various degrees of confusional state without motor symptoms. We found no significant correlation between edema volume, distribution and any clinical feature, including new post‐operative neurological symptoms. The retrospective computed tomography analysis showed that peri‐electrode hypodensity consistent with edema is absent at early post‐operative imaging but is common at scans performed >3 days after surgery.ConclusionsPeri‐electrode edema is a common, transient reaction to DBS lead placement and a convincing relation between edema and post‐operative clinical status is lacking.
A hybrid data envelopment analysis and multi‐attribute decision making approach to sustainability assessment
Authors: Keshavarz Esmaeil , Toloo Mehdi 
Published: October 2018

AbstractThe concept of sustainability consists of three main dimensions: environmental, techno‐economic, and social. Measuring the sustainability status of a system or technology is a significant challenge, especially when it needs to consider a large number of attributes in each dimension of sustainability. In this study, we first propose a hybrid approach, involving data envelopment analysis (DEA) and a multi‐attribute decision making (MADM) methodologies, for computing an index for each dimension of sustainability, and then we define the overall sustainability index as the mean of the three measured indexes. Towards this end, we define new concepts of efficiency and cross‐efficiency of order (p, q) where p and q are the number of inputs and outputs, respectively. For a given (p, q), we address the problem of finding efficiency of order (p, q) by developing a novel DEA‐based selecting method. Finally, we define the sustainability index as a weighted sum of all possible cross‐efficiencies of order (p, q). Form a computational viewpoint, the proposed selecting model significantly decreases the computational burden in comparison with the successive solving of traditional DEA models. A case study of the electricity‐generation technologies in the United Kingdom is taken as a real‐world example to illustrate the potential application of our method.
The effects of fluoxetine on the human adipose‐derived stem cell proliferation and differentiation
Authors: Khademi Marzieh , Taghizadeh Ghavamabadi Razieh , Taghavi Mohammad M. , Shabanizadeh Ahmad , Shariati‐kohbanani Mehdi , Hassanipour Mahsa , Taghipour Zahra 
Published: October 2018

AbstractFluoxetine is one of the most commonly used antidepressants. Fluoxetine could prevent the mesenchymal stem cell differentiation in lung fetus of rat. Moreover, the mesenchymal stem cells are also present in adult tissues. Therefore, in the current study, we aimed to investigate the effects of fluoxetine (FLX) on both proliferation and adipogenic/osteogenic differentiation of human adipose‐derived stem cells (ADSCs). After culturing of human ADSCs, these cells were treated with two concentrations of FLX (10 and 20 μm). Then, cells were differentiated by adding osteogenic and adipogenic media. The effect of FLX on human ADSCs proliferation was evaluated by MTT assay. Fluoxetine role on adipogenic and osteogenic differentiation of human ADSCs was analyzed by oil red and alizarin red staining and RT‐PCR reaction. According to MTT assay, FLX showed a time‐ and concentration‐dependent proliferation response and eventually decreased human ADSCs proliferation. RT‐PCR analysis indicated that FLX significantly diminished the expression of osteogenesis‐related genes such as RUNX2 and alkaline phosphatase (ALP). Data also revealed a significant reduction in the expression of peroxisome proliferator‐activated receptor γ (PPARγ) and fatty acid‐binding protein (FABP) (specific genes of adipogenic lineage). In addition, FLX decreased mineralized matrix and the amount of lipid droplets in human ADSCs by staining methods. Our observation demonstrated that the effects of FLX may be time‐dependent. This drug possesses an increasing phase in proliferation and survival of human ADSCs (first 24 h) following a decreasing phase (after 48 h). Moreover, FLX could attenuate both osteogenic and adipogenic differentiation of human ADSCs.
Structural reliability assessment of cracked pipes: The role of probability of detection data
Authors: Mussini Rodolfo , Cancela Héctor , Clarke Thomas 
Published: October 2018

AbstractThe structural reliability of industrial pipes, including those in the nuclear, oil, and gas industries, has a significant impact on the safety of people and the environment. This work aims to develop a computational structural reliability model method in conjunction with the failure assessment diagram method and the user‐defined probability of detection curves of non‐destructive testing are used. The concept of “reliability factor of a repair” is proposed. Then, the effects of the pipe inspection considering different user‐defined probability of detection curves and different values of the reliability factor of a repair on probability of failure are discussed. The main results include the identification of cases where performing repairs do not guarantee an improved reliability, as well as the consequences of considering the repair as a “perfect process” which result in non‐conservative assessments.
Nutritive value of ensiled maize stover from nine different varieties harvested at three different stages of maturity
Authors: Terler Georg , Gruber Leonhard , Knaus Wilhelm F. 
Published: October 2018

AbstractNutrient composition and digestibility of stover contribute markedly to the nutritive value of forage maize in cattle feeding. Low stover digestibility limits the quality of whole plant maize silage (WPMS) and should therefore be prevented by optimizing management of WPMS production. A project was carried out to analyse nutrient composition and ruminal nutrient degradability of ensiled stover of nine different current maize varieties, which were planted in 3 years and harvested at three maturity stages (50, 55 and 60% ear dry‐matter [DM] content). Variety and harvest date had a significant impact (p < 0.05) on crude protein (CP) and metabolizable energy content, whereas fibre content and non‐fibre components were not affected by these factors. In contrast, the potential and effective degradability (ED) of organic matter (OM), CP and neutral detergent fibre (NDF) were significantly influenced by variety and harvest date. The ED5 (ED at 5% per hour passage rate) of different varieties ranged from 22.9% to 29.3% for OM, from 66.2% to 71.4% for CP and from 17.3% to 20.5% for NDF. The ED5 of OM, CP and NDF declined significantly by 4.1%, 2.5% and 2.1% units between the second and third maturity stage. Almost all investigated parameters were significantly influenced by year. Significant differences between varieties indicate that there is a potential for improvement of stover degradability through breeding. Harvest ear DM content should not exceed 55%, because nutritive value of ensiled stover declines significantly beyond this value, which could negatively affect WPMS quality in cattle feeding.