bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fe/Co-modified Enteromorpha bio-hydrochar enhanced anaerobic digestion of chicken manure with sulfadimethazine: focusing on synergistic mechanism and microbial community succession
Authors: Liu Yutong , Peng Ziyu , Hu Zhengguang , Xue Hanhan , Qiao Junpeng , Niu Qigui 
Published: November 2024

AbstractResidual antibiotics in chicken manure may interfere with the stability of anaerobic digestion (AD) and inhibit resource utilization efficiency. In this study, we aimed to enhance chicken manure bio-methanation in AD with high-concentration of sulfamethazine (SMZ) by adding metal (Fe, Co)-modified Enteromorpha-based hydrochar (Co-HC, Fe-HC). The results showed that Fe-HC and Co-HC increased the degree of acidogenesis by 1.25 times and 1.58 times, respectively. The maximum protein concentration in EPS was increased by 47.64% and 72.5% after adding Fe-HC and Co-HC. However, only Co-HC demonstrated notable improvements in both methane production and SMZ removal efficiency. Electrochemical analysis showed that Co-HC possessed a richer variety of oxygen and nitrogen functional groups, along with superior electron exchange capabilities compared to Fe-HC. Furthermore, microbiological assessments revealed that Co-HC enriched syntrophic bacteria (such as Syntrophomonas and Mesotoga), facilitating direct interspecies electron transfer (DIET) and subsequently enhancing biomethane production. The abundance of genes involved in electron transfer increased significantly with Co-HC, with a maximum increase of 75.86% in Co1.5-HC treatment. Additionally, the elimination of antibiotic resistance genes (sul1, sul2) increased by 65.66% in the Co1.5-HC treatment. This study offers a theoretical foundation and empirical support for the synergistic improvement of livestock and poultry manure containing high antibiotic concentrations, thereby helping to overcome challenges posed by recalcitrant substances.
Graphical Abstract
Assessment of therapeutic response to photodynamic therapy with the Zn-Phthalocyanine RLP068/Cl versus topical Clindamycin in patients affected by Hidradenitis Suppurativa: a comparative clinical pilot study
Authors: Rosi E. , Prignano F. , Viola S. , Venturini M. , Pimpinelli N. , Calzavara-Pinton P. 
Published: November 2024

AbstractHidradenitis suppurativa is a chronic skin disorder characterized by painful inflammatory nodules and abscesses, significantly impacting patients’ quality of life. Current treatment strategies, including topical antibiotics, often yield limited efficacy and pose risks of antibiotic resistance. Photodynamic therapy has emerged as a potential option, with RLP068/Cl (ELKOFAST®, non-sterile formulation) showing promising efficacy due to its broad-spectrum bactericidal activity. We conducted a pilot study assessing the therapeutic response to photodynamic therapy with RLP068/Cl versus topical clindamycin gel in patients affected by hidradenitis suppurativa of Hurley score I, II, and III. Results revealed higher efficacy of photodynamic therapy in combination with RLP068/Cl, particularly in mild cases. Its efficacy remains reliable even in more severe cases when combined with adalimumab. The observed faster lesion improvement and pain relief were ascribed to the bactericidal effects of RLP068/Cl against Gram+ and Gram− bacteria. Furthermore, photoactivated RLP068/Cl was well tolerated with no adverse events reported. Therefore, photodynamic therapy following RLP068/Cl application represents a novel therapeutic option for hidradenitis suppurativa with potential implications for antibiotic stewardship in dermatology.
Graphical abstract
The weak Ramsey property and extreme amenability
Authors: Bartoš Adam , Bice Tristan , Dasilva Barbosa Keegan , Kubiś Wiesław 
Published: November 2024

Abstract
We extend the Kechris–Pestov–Todorčević correspondence to weak Fraïssé categories and automorphism groups of generic objects. The new ingredient is the weak Ramsey property. We demonstrate the theory on several examples including monoid categories, the category of almost linear orders and categories of strong embeddings of trees.
Increasing subsequences, matrix loci and Viennot shadows
Authors: Rhoades Brendon 
Published: November 2024

Abstract
Let

${\mathbf {x}}_{n \times n}$

be an

$n \times n$

matrix of variables, and let

${\mathbb {F}}[{\mathbf {x}}_{n \times n}]$

be the polynomial ring in these variables over a field

${\mathbb {F}}$

. We study the ideal

$I_n \subseteq {\mathbb {F}}[{\mathbf {x}}_{n \times n}]$

generated by all row and column variable sums and all products of two variables drawn from the same row or column. We show that the quotient

${\mathbb {F}}[{\mathbf {x}}_{n \times n}]/I_n$

admits a standard monomial basis determined by Viennot’s shadow line avatar of the Schensted correspondence. As a corollary, the Hilbert series of

${\mathbb {F}}[{\mathbf {x}}_{n \times n}]/I_n$

is the generating function of permutations in

${\mathfrak {S}}_n$

by the length of their longest increasing subsequence. Along the way, we describe a ‘shadow junta’ basis of the vector space of k-local permutation statistics. We also calculate the structure of

${\mathbb {F}}[{\mathbf {x}}_{n \times n}]/I_n$

as a graded

${\mathfrak {S}}_n \times {\mathfrak {S}}_n$

-module.
Improved use of antibiotics following implementation of antimicrobial stewardship in a neonatal intensive care unit
Authors: Karelsdottir Arna Yr , Oskarsdottir Thorunn , Hoffritz Olof Eir , Thorkelsson Thordur , Haraldsson Asgeir , Thors Valtyr 
Published: November 2024

AbstractIntroduction:Inappropriate antibiotic use in infants can have multiple adverse effects and contribute to the development of bacteria resistant to antimicrobials. Antimicrobial stewardship programs can reduce unnecessary antibiotic use in children. The aim of this study was to evaluate the effect of an antimicrobial stewardship program implemented in 2017 in the Neonatal Intensive Care Unit (NICU) at The Children’s Hospital Iceland.Materials and methods:The study included all infants who were admitted to the NICU during the study period (January 1st 2012–October 31st 2020). Data was collected from hospital records. Three periods were defined: preimplementation (2012–2014), peri-implementation (2015–2016) and postimplementation (2017–October 2020). Antibiotic use was quantified using days of therapy (DOT) per 1000 bed days (BD). For statistical analysis the pre- and postimplementation periods were compared.Results:Antibiotics were administered in 38.6% (1372) of admissions to the NICU during the study period. Antimicrobial use per year decreased from 584.6 to 317.1 DOT/1000 BD per year (P < 0.001). Use of broad-spectrum antibiotics decreased significantly. The average number of BD per month decreased from 297.8 to 220.9 BD/month (P = 0.0096). There were no significant changes in the length of stay for each infant or the proportion of readmissions or retreatment.Conclusion:Increased awareness of appropriate use of antimicrobials in the NICU led to shorter treatments and less use of broad-spectrum antibiotics. No increase in adverse effects such as readmissions or retreatment was observed.
Investigation of the relationship of sleep disorder occurring in fibromyalgia with central nervous system and pineal gland volume
Authors: Çiçek Fatih , Uçar İlyas , Seber Turgut , Ülkü Demir Fatma Gül , Çiftçi Ali Türker 
Published: November 2024

Abstract

Objective:
Mechanisms of sleep disorders in fibromyalgia (FM) patients, such as insomnia, early morning awakenings and poor quality sleep, have not yet been proven and no consistent and effective treatment is yet available. The aim of this study was to investigate the pineal gland volume and the relationship between total fibre count, total fibre volume and total fibre length of the spinoreticular tract involved in regulation of sleep and wakefulness in terms of the mechanism of sleep disturbance.

Methods:
This study included only female cases, 31 with fibromyalgia and 31 controls. Pittsburgh Sleep Quality Index was used to assess sleep quality. Tractography of targeted pathway from brain diffusion MR images was calculated in Diffusion Studio Imaging (DSI) Studio programme and the volume of the pineal gland was calculated in ITK-SNAP programme.

Results:
The mean volume of the pineal gland was higher in control group (218.84 ± 64.45 mm3) than in fibromyalgia group (174.77 ± 48.65 mm3), which was statistically significant (p = 0.004). However, there was no statistically significant difference between two groups in total spinoreticular tract (TSRT), total volume (TSRTV), TSRT fractional anisotropy, TSRT mean diffusion, TSRT axial diffusion and TSRT radial diffusion of spinoreticular tract, which is involved in the regulation of sleep and wakefulness (p > 0.05).

Conclusion:
In conclusion, it is thought that the endocrine system may be more related to sleep disturbance in individuals with FM than central nervous system. Therefore, we believe that it may be more appropriate to work on the endocrine system rather than neural system in the treatment of sleep disturbance in patients with FM.
WALLABY Pilot Survey: Public data release of ∼ 1800 H i sources and high-resolution cut-outs from Pilot Survey Phase 2
Authors: Murugeshan C. , Deg N. , Westmeier T. , Shen A. X. , For B.-Q. , Spekkens K. , Wong O. I. , Staveley-Smith L. , Catinella B. , Lee-Waddell K. , Dénes H. , Rhee J. , Cortese L. , Goliath S. , Halloran R. , van der Hulst J. M. , Kamphuis P. , Koribalski B. S. , Kraan-Korteweg R. C. , Lelli F. , Venkataraman P. , Verdes-Montenegro L. , Yu N. 
Published: November 2024

Abstract
We present the Pilot Survey Phase 2 data release for the Wide-field ASKAP L-band Legacy All-sky Blind surveY (WALLABY), carried-out using the Australian SKA Pathfinder (ASKAP). We present 1760 H i detections (with a default spatial resolution of 30′′) from three pilot fields including the NGC 5044 and NGC 4808 groups as well as the Vela field, covering a total of

$\sim 180$

deg

$^2$

of the sky and spanning a redshift up to

$z \simeq 0.09$

. This release also includes kinematic models for over 126 spatially resolved galaxies. The observed median rms noise in the image cubes is 1.7 mJy per 30′′ beam and 18.5 kHz channel. This corresponds to a 5

$\sigma$

H i column density sensitivity of

$\sim 9.1\times10^{19}(1 + z)^4$

cm

$^{-2}$

per 30′′ beam and

$\sim 20$

km s

$^{-1}$

channel and a 5

$\sigma$

H i mass sensitivity of

$\sim 5.5\times10^8 (D/100$

Mpc)

$^{2}$

M

$_{\odot}$

for point sources. Furthermore, we also present for the first time 12′′ high-resolution images (“cut-outs”) and catalogues for a sub-sample of 80 sources from the Pilot Survey Phase 2 fields. While we are able to recover sources with lower signal-to-noise ratio compared to sources in the Public Data Release 1, we do note that some data quality issues still persist, notably, flux discrepancies that are linked to the impact of side lobes associated with the dirty beams due to inadequate deconvolution. However, in spite of these limitations, the WALLABY Pilot Survey Phase 2 has already produced roughly a third of the number of HIPASS sources, making this the largest spatially resolved H i sample from a single survey to date.
Challenging Classical Music’s Genre Conventions: Findings from a Project on Youth Voice in Instrumental Education
Authors: BULL ANNA 
Published: November 2024

AbstractThis article explores classical music education through analysing findings from a project on embedding ‘youth voice’ within instrumental teaching and learning. Drawing on theorizations of classical music as a genre, I describe how the young people in this project saw classical music’s genre conventions as working against a youth voice approach. The article also outlines the ways in which youth voice was shaped through social relations in this space as well as the ‘institutional ecology’ of music education. I argue that embedding youth voice approaches in instrumental education will only be effective if the genre itself is open to transformation.
Causal association of plasma n-3 PUFA with peptic ulcer disease: a two-sample Mendelian randomisation study
Authors: Dai Zebin , Wang Qinjian , He Bingbing , Shi Fang , Chen Wei , Jiang Qingxi , Zhou Dan , Xue Zhanxiong , Yang Bo 
Published: November 2024

AbstractDietary n-3 PUFA may have potential benefits in preventing peptic ulcer disease (PUD). However, data from observational epidemiological studies are limited. Thus, we conducted a Mendelian randomisation analysis to reveal the causal impact of n-3 PUFA on PUD. Genetic variants strongly associated with plasma levels of total or individual n-3 PUFA including plant-derived α-linolenic acid and marine-derived EPA, DPA and DHA were enrolled as instrumental variables. Effect size estimates of the n-3 PUFA-associated genetic variants with PUD were evaluated using data from the UK biobank. Per one sd increase in the level of total n-3 PUFA in plasma was significantly associated with a lower risk of PUD (OR = 0·91; 95 % CI 0·85, 0·99; P = 0·020). The OR were 0·81 (95 % CI 0·67, 0·97) for EPA, 0·72 (95 % CI 0·58, 0·91) for DPA and 0·87 (95 % CI 0·80, 0·94) for DHA. Genetically predicted α-linolenic acid levels in plasma had no significant association with the risk of PUD (OR = 5·41; 95 % CI 0·70, 41·7). Genetically predicted plasma levels of n-3 PUFA were inversely associated with the risk of PUD, especially marine-based n-3 PUFA. Such findings may have offered an effective and feasible strategy for the primary prevention of PUD.
Renaissance Self-Fashioning after 44 Years: Hybridity, Conversos, Individuation, and littérature totale
Authors: Terry-Roisin Elizabeth 
Published: November 2024

Abstract
While Stephen Greenblatt’s 1980 book, Renaissance self-fashioning: from More to Shakespeare, was methodologically innovative within the field of literary criticism, his work also grew from the roots of Jacob Burckhardt’s old cultural history, and his method of new historicism developed alongside the new cultural history. Although certain parts of Burckhardt’s arguments have been discarded, the work of Greenblatt and others has continued to build upon his foundation. Courtiership, anxiety, and the relationship between outward and interior identities, text and context, hybridity, and individuation are all useful concepts for constructing less monolithic understandings of early modern identities. With a European scale, this article traces early modern historiography and literary criticism from the nineteenth century to 2024 and introduces historical examples of identity formation from early modern England, France, Iberia, the Italian peninsula, and the Holy Roman Empire. The article reflects upon early modern examples of self-fashioning in the light of Burckhardt, the Annales, Greenblatt, and others who have contributed to our understanding of agency and identity up to the present day, arguing that these historians and literary scholars have worked together to answer questions that are fundamentally psychological in nature.
Henneguya patriciai n. sp. (Cnidaria: Myxosporea) parasitizing Leporinus friderici (Bloch 1794) from Tartarugalzinho river, eastern Amazon
Authors: Amaral de Carvalho Abthyllane , de Oliveira Nascimento Lilia Suzane , Pantoja dos Reis Luize Cristine , da Silva Ferreira Roger Leomar , Morais Saturo Cardoso , Geise Elane Guerreiro , Videira Marcela Nunes , Matos Edilson Rodrigues 
Published: November 2024

Abstract
The Amazon basin has the largest number of fish in the world, and among the most common fishes of the Neotropical region, the threespot (Leporinus friderici) is cited, which in relation to its microparasitic fauna, has described only 1 species of the genus Henneguya, Henneguya friderici. The Myxozoa class is considered an obligate parasite, being morphologically characterized by spores formed by valves connected by a suture line. This study describes a new species of Henneguya sp. in the Amazon region for L. friderici. This parasite was found in the host's pyloric caeca and caudal kidney, with mature spores with a total spore length of 38.4 ± 2.5 (35.9–40.9) μm; the spore body 14.4 ± 1.1 (13.3–15.5) μm and 7.3 ± 0.6 (6.7–7.9) μm wide. Regarding its 2 polar capsules, they had a length of 5.1 ± 0.4 (4.7–5.5) μm and a width of 2.0 ± 0.1 (1.9–2.1) μm in the same pear-shaped, and each polar capsule contained 9–11 turns. Morphological and phylogenetic analyses denote that this is a new species of the genus Henneguya.
Identification of optimum scopes of environmental drivers for schistosome-transmitting Oncomelania hupensis using agent-based model in Dongting Lake Region, China
Authors: Huang Junhui , Wang Jiamin , Gong Yanfeng , Xu Ning , Zhou Yu , Zhu Liyun , Shi Liang , Chen Yue , Jiang Qingwu , Zhou Yibiao 
Published: November 2024

Abstract
Oncomelania hupensis (O. hupensis), the sole intermediate host of Schistosoma japonicum, greatly influence the prevalence and distribution of schistosomiasis japonica. The distribution area of O. hupensis has remained extensive for numerous years. This study aimed to establish a valid agent-based model of snail density and further explore the environmental conditions suitable for snail breeding. A marshland with O. hupensis was selected as a study site in Dongting Lake Region, and snail surveys were monthly conducted from 2007 to 2016. Combined with the data from historical literature, an agent-based model of snail density was constructed in NetLogo 6.2.0 and validated with the collected survey data. BehaviorSpace was used to identify the optimal ranges of soil temperature, pH, soil water content, and vegetation coverage for snail growth, development and reproduction. An agent-based model of snail density was constructed and showed a strong agreement with the monthly average snail density from the field surveys. As soil temperature increased, the snail density initially rose before declining, reaching its peak at around 21°C. There were similar variation patterns for other environmental factors. The findings from the model suggested that the optimum ranges of soil temperature, pH, soil water content and vegetation coverage were 19°C to 23 °C, 6.4 to 7.6, 42% to 75%, and 70% to 93%, respectively. A valid agent-based model of snail density was constructed, providing more objective information about the optimum ranges of environmental factors for snail growth, development and reproduction.
A living reasonable account: on the status of Timaeus’ eikōs logos (again)
Authors: Petrucci Federico M. 
Published: November 2024

AbstractIs an account of hair or nails as negotiable as one of the Demiurge? It should not be. The aim of this paper is to supplement existing interpretations of Timaeus’ eikōs logos in order to provide well-grounded answers to this and similar questions. More specifically, I shall demonstrate that Timaeus’ account cannot be confined to a single epistemological field, namely that of unstable likeliness, because it exhibits a much more nuanced and graduated structure, just as do the realities it deals with, and, as a whole, leaves minimal room for refutation and scepticism.
Investigation of the effect of serotonin-activated semen washing medium on sperm motility at the molecular level: a pilot study
Authors: Moshfeghi Elnaz , Yilmazer Yasemin , Dogan Sinem , Aydin Turgut , Findikli Necati , Ozbek Tulin 
Published: November 2024

SummaryIn Assisted Reproductive Technologies (ART), efficient sperm preparation is vital for successful fertilization, with washing media enhancing the process. This pilot study examines the molecular-level impact of a new serotonin-containing sperm-washing medium (Prototype) on sperm motility and ROS metabolism, comparing it with commercially available media (Origio and Irvine). Semen samples from thirty-one individuals underwent preparation using the swim-up method post-semen analysis. Each sample was separately washed with the Prototype, Origio and Irvine mediums. ROS formation was determined through flow cytometric, and AT2R and PRDX2 protein levels, associated with sperm motility, were assessed via Western blot. Statistical evaluation compared the findings among the three outlined media. Significant differences were found among three washing media in terms of total and progressive motility. The Prototype medium showed the highest increase in both total (66%) and progressive motility (59%), while the control group exhibited the lowest increases (41% and 27.7%, respectively). Regarding ROS levels, the prototype (11.5%) and Origio (10.7%) groups demonstrated a notable decrease, contrasting with Irvine (25.8%). Molecular assessment revealed a significant elevation in AT2R protein levels in the prototype medium (59%), compared to other media. Additionally, an increase in PRDX2 protein levels was observed in the prototype medium, although this didn’t reach statistical significance. Serotonin-activated washing media for sperm preparation can be a suitable choice for selecting high-quality sperm in ART. A broader molecular analysis with a larger sample size is required to explore the mechanisms and effectiveness of using a serotonin-containing sperm-washing medium in routine ART.
‘Are You Really Anglicans?’ Reflections on Church Planting, Innovation and Ecclesiastical Authority in the Church of England
Authors: Cockayne Joshua 
Published: November 2024

Abstract
This paper seeks to grapple with questions of polity and innovation in the Church of England and specifically to explore the place of non-parochial forms of church within this tradition of Anglicanism. The paper begins by outlining recent developments within the Church of England around the ‘mixed ecology’ and church planting, before summarizing Alison Milbank’s recent critique of these changes. Then, building on in example of the Guild Churches Act from London Diocese in the mid-twentieth century, it is argued that within a commitment to Anglican polity there lies a vision for creativity in mission which might sometimes mean the pursuing non-parochial forms of ministry.
Late Miocene Uplift and Exhumation of the Lesser Himalaya Recorded by Clumped Isotope Compositions of Detrital Carbonate
Authors: Ryb U. , Ponton C. , France‐Lanord C. , Yoshida K. , Eiler J. M. 
Published: November 2024

AbstractThe Himalaya orogen evolved since the Eocene as the Tethyan‐, Greater‐, Lesser‐ and Sub‐Himalaya thrust sheets were uplifted and exhumed in sequence. Reconstructing the provenance of sediment in Himalayan River systems can inform on stages in the tectonic history of the orogen. Here, we analyze the oxygen, carbon and “clumped” isotope compositions of carbonate minerals from Himalayan bedrock, Ganga River sediments and Bengal Fan turbidite deposits. We demonstrate that river sediments consist of a mixture of Himalayan‐derived and authigenic calcite precipitated in the river system. The relative abundance and clumped isotope apparent temperatures of detrital calcite in turbidite deposits decreased between the Late Miocene and Pliocene, while chemical weathering intensity did not increase during this interval. Considered together, these results reflect the establishment of the Lesser Himalaya as an important carbonate sediment source for Himalayan rivers, driven by the uplift and exhumation of this thrust sheet.