bluuebunny/crossref_metadata_2025_split huggingface dataset:
Looking after patients with hip fracture in low- and middle-income countries
Authors: Tabu Irewin , Ivers Rebecca , Costa Matt L. 
Published: December 2024

In the UK, multidisciplinary teamwork for patients with hip fracture has been shown to reduce mortality and improves health-related quality of life for patients, while also reducing hospital bed days and associated healthcare costs. However, despite rapidly increasing numbers of fragility fractures, multidisciplinary shared care is rare in low- and middle-income countries around the world. The HIPCARE trial will test the introduction of multidisciplinary care pathways in five low- and middle-income countries in South and Southeast Asia, with the aim to improve patients’ quality of life and reduce healthcare costs.Cite this article: Bone Joint J 2024;106-B(12):1369–1371.
In vivo reduction of biofilm seeded on orthopaedic implants
Authors: Cordero García-Galán Enrique , Medel-Plaza Marina , Pozo-Kreilinger José J. , Sarnago Héctor , Lucía Óscar , Rico-Nieto Alicia , Esteban Jaime , Gomez-Barrena Enrique 
Published: December 2024

AimsElectromagnetic induction heating has demonstrated in vitro antibacterial efficacy over biofilms on metallic biomaterials, although no in vivo studies have been published. Assessment of side effects, including thermal necrosis of adjacent tissue, would determine transferability into clinical practice. Our goal was to assess bone necrosis and antibacterial efficacy of induction heating on biofilm-infected implants in an in vivo setting.MethodsTitanium-aluminium-vanadium (Ti6Al4V) screws were implanted in medial condyle of New Zealand giant rabbit knee. Study intervention consisted of induction heating of the screw head up to 70°C for 3.5 minutes after implantation using a portable device. Both knees were implanted, and induction heating was applied unilaterally keeping contralateral knee as paired control. Sterile screws were implanted in six rabbits, while the other six received screws coated with Staphylococcus aureus biofilm. Sacrifice and sample collection were performed 24, 48, or 96 hours postoperatively. Retrieved screws were sonicated, and adhered bacteria were estimated via drop-plate. Width of bone necrosis in retrieved femora was assessed through microscopic examination. Analysis was performed using non-parametric tests with significance fixed at p ≤ 0.05.ResultsThe width of necrosis margin in induction heating-treated knees ranged from 0 to 650 μm in the sterile-screw group, and 0 to 517 μm in the biofilm-infected group. No significant differences were found between paired knees. In rabbits implanted with sterile screws, no bacteria were detected. In rabbits implanted with infected screws, a significant bacterial load reduction with median 0.75 Log10 colony-forming units/ml was observed (p = 0.016).ConclusionInduction heating was not associated with any demonstrable thermal bone necrosis in our rabbit knee model, and might reduce bacterial load in S. aureus biofilms on Ti6Al4V implants.Cite this article: Bone Joint Res 2024;13(12):695–702.
A systematic review and mapping exercise to assess the content validity of patient-reported outcome measures for adults having reconstructive surgery of the lower limb
Authors: Lister Jennie , James Sophie , Sharma Hemant K. , Hewitt Catherine , Fulbright Helen , Leggett Heather , McDaid Catriona 
Published: December 2024

AimsLower limb reconstruction (LLR) has a profound impact on patients, affecting multiple areas of their lives. Many patient-reported outcome measures (PROMs) are employed to assess these impacts; however, there are concerns that they do not adequately capture all outcomes important to patients, and may lack content validity in this context. This review explored whether PROMs used with adults requiring, undergoing, or after undergoing LLR exhibited content validity and adequately captured outcomes considered relevant and important to patients.MethodsA total of 37 PROMs were identified. Systematic searches were performed to retrieve content validity studies in the adult LLR population, and hand-searches used to find PROM development studies. Content validity assessments for each measure were performed following Consensus-based Standards for the selection of health measurement Instruments (COSMIN) guidelines. A mapping exercise compared all PROMs to a conceptual framework previously developed by the study team (‘the PROLLIT framework’) to explore whether each PROM covered important and relevant concepts.ResultsThe systematic searches found 13 studies, while hand searches found 50 PROM development studies, and copies of all 37 measures. Although several studies discussed content validity, none were found which formally assessed this measurement property in the adult LLR population. Development of many PROMs was rated as inadequate, no PROM had sufficient content validity in the study population, and none covered all areas of the PROLLIT framework. The LIMB-Q was the most promising and comprehensive measure assessed, although further validation in a wider sample of LLR patients was recommended.ConclusionCurrent PROMs used in adults requiring, undergoing, or after undergoing LLR lack content validity and do not assess all important and relevant outcomes. There is an urgent need for improved outcome measurement in this population. This can be achieved through development of a new PROM, or through validation of existing measures in representative samples.Cite this article: Bone Jt Open 2024;5(12):1049–1066.
Kajian Elevasi Lantai Dermaga Berdasarkan Integrasi Pengaruh Pasang Surut, Gelombang dan Kenaikan Muka Laut di Pelabuhan Tanjung Emas Kota Semarang
Authors: Hanun Alain Shofia , Ismunarti Dwi Haryo , Helmi Muhammad 
Published: December 2024

Pelabuhan Tanjung Emas merupakan salah satu pelabuhan di Indonesia yang terletak di Kota Semarang, Jawa Tengah. Perkembangan lalu lintas perdagangan dan bertambahnya arus transportasi di pelabuhan, maka perlu dilakukan rencana pengembangan pembangunan pelabuhan. Penelitian ini dilakukan untuk menghitung elevasi lantai dermaga . Data primer yang digunakan adalah data pasang surut bulan Maret 2022. Data sekunder meliputi data angin, data sea level rise, dan data pasang surut dari IOC Sea Level Monitoring. Metode yang dilakukan untuk mengolah pasang surut adalah Admiralty dan Least Square. Hasil penelitian menunjukkan tipe pasang surut campuran condong ke tunggal dengan nilai HHWL 105.282 cm. Hasil peramalan gelombang dari data angin selama 10 tahun didapat nilai tinggi gelombang signifikan (Hs) sebesar 0,9287 m dan nilai periode signifikan (Ts) sebesar 5,0210 detik dan nilai wave set up (Sw) diperoleh sebesar 0,16 m. Nilai sea level rise yang didapatkan sebesar 0.32 cm/tahun. Nilai Design Water Level (DWL) didapatkan dengan menjumlahkan nilai HHWL, wave set up, dan SLR sehingga didapat nilai sebesar 124 cm. Sehingga, nilai elevasi lantai dermaga yang diperoleh adalah 363,2 cm sehingga dapat dikatakan aman.
Analisis Konsentrasi Dan Sebaran Mikroplastik Di Muara Sungai Bedahan, Wonokerto, Kabupaten Pekalongan
Authors: Damanik Doding Akka , Widada Sugeng , Widiaratih Rikha 
Published: December 2024

Kabupaten Pekalongan dikenal sebagai kota industri, dimana terdapat berbagai aktivitas dan kegiatan antropogenik. Hasil dari aktivitas antropogenik tersebut menghasilkan buangan limbah cair dan padat. Perairan bedahan merupakan salah satu wilayah yang menjadi dampak dari hasil buangan limbah dari aktivitas antropogenik.Penelitian ini bertujuan untuk mengetahui kelimpahan dan sebaran mikroplastik di air dan sedimen di muara Sungai Bedahan, Pekalongan. Sungai Bedahan merupakan sungai terbesar dengan banyak aktivitas antropogenik di sekitarnya. Sampling dilakukan pada tanggal 25 Juni 2023 saat musim timur di Muara Sungai Bedahan, Kabupaten Pekalongan. Penelitian dilakukan pada keadaan surut menuju pasang dengan pengambilan data lapangan berupa sampel mikroplastik pada 8 titik dan sedimen diambil di 3 titik . Hasil menunjukkan bahwa kelimpahan mikroplastik sebesar 99 – 347 partikel/m3 pada sampel air dan 653 – 1368 partikel/kg pada sampel sedimen. Jenis mikroplastik yang paling mendominasi yaitu fragment dan film serta warna yang paling banyak ditemukan adalah hitam (>50%). Kelimpahan dan sebaran mikroplastik terbesar pada sampel air terdapat di perairan lepas dan pada sampel sedimen kelimpahan dan sebaran mikroplastik terbesar terdapat di daerah pesisir. Sebaran mikroplastik dipengaruhi oleh aktivitas antropogenik serta hidrodinamika. arus bergerak dari arah timur menuju ke barat. Dari hasil model arus didapat kecepatan tertinggi sebesar 0.225 m/s. Arus memiliki peran penting untuk distribusi mikroplastik perairan. Selain faktor arus, sebaran mikroplastik pada permukaan air dipengaruhi oleh debit air sungai yang membawa mikroplastik menuju ke daerah lautan.
Analisis Terjadinya Gelombang Tinggi Akibat Pola Pergerakan Angin Terkait Keselamatan Pelayaran di Perairan Utara Jawa Tengah
Authors: Retika Ferancha , Sugianto Denny Nugroho , Widiaratih Rikha 
Published: December 2024

Laut Jawa Utara merupakan jalur pelayaran yang penting untuk perekonomian, dan gelombang tinggi menimbulkan ancaman terhadap keselamatan pelayaran. Studi ini menganalisis hubungan antara pergerakan pola angin dan kejadian gelombang tinggi di Laut Jawa Utara, dengan fokus pada keselamatan navigasi. Penelitian ini menggunakan data angin dari European Centre for Medium-Range Weather Forecasts (ECMWF). Data ini digunakan untuk mengidentifikasi pola angin dominan yang berkontribusi terhadap kejadian gelombang tinggi. Metode yang digunakan adalah metode DNS untuk peramalan gelombang, metode Weibull dan Gumbel untuk peramalan gelombang tinggi 2-100 tahun yang akan datang. Hasil penelitian menunjukkan bahwa pola angin dari arah tenggara dan barat laut merupakan penyebab utama gelombang tinggi di Laut Jawa Utara. Gelombang tertinggi terjadi selama musim muson barat daya, dengan tinggi gelombang mencapai 2 meter. Peramalan gelombang periode ulang 2, 5, 10, 25, 50 dan 100 tahun menggunakan perhitungan Weibull lebih sesuai di Lokasi laut lepas dan pesisir seperti pada stasiun 4 didapatkan hasil berturut-turut adalah 2.11 m, 2.31 m, 2.5 m, 2.77 m, 3 m, dan 3.24 m. Sedangkan peramalan gelombang periode ulang Gumbel lebih sesuai digunakan di daerah pesisir seperti pada stasiun 3 didapatkan hasil secara berturut-turut adalah 1.51 m, 1.73 m, 1.87 m, 2.06 m, 2.20 m dan 2.33 m.
Preparasi dan Karakterisasi Bioplastik dari Limbah Ekstraksi Karagenan Rumput Laut Kappaphycus alvarezii (Doty) Doty ex P. C. Silva, 1966 dengan Pemlastis Gliserol
Authors: Ridlo Ali , Sabdono Agus , Subagiyo Subagiyo , Ario Raden , Pratikto Ibnu , Hartati Retno 
Published: December 2024

The carrageenan production process from Kappaphycus alvarezii seaweed produces solid waste of 60%-70% w/w, primarily composed of cellulose, which can be used for bioplastic films. This research aims to determine the effect of glycerol plasticizer addition on the characteristics of K. alvarezii waste-based bioplastics. Bioplastics were made by mixing 50 g of wet waste with 90 mL of distilled water, homogenized at 70°C for 30 minutes. Glycerol (0%, 1%, 2%, 3%, 4%) was added, with water to a total volume of 150 mL, and homogenized again for 30 minutes. The solution was poured into a polypropylene mold and dried at 60°C for 24 hours. Results showed glycerol increased transparency and elongation but reduced tensile strength and water resistance. The addition of 1% glycerol produced bioplastics with the best characteristics, meeting Japanese Industrial Standards. FTIR and SEM showed similar bioplastic properties across treatments. This research indicates that K. alvarezii carrageenan extraction waste is promising for packaging material and bioplastic production. Proses produksi karagenan dari rumput laut Kappaphycus alvarezii menghasilkan limbah padat sebesar 60%-70% w/w, terutama terdiri dari selulosa yang dapat digunakan untuk film bioplastik. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan plastisizer gliserol terhadap karakteristik bioplastik limbah K. alvarezii. Bioplastik dibuat dengan mencampurkan 50 g limbah basah dengan 90 mL akuades, dihomogenkan pada suhu 70°C selama 30 menit. Gliserol (0%, 1%, 2%, 3%, 4%) ditambahkan hingga volume 150 mL, dihomogenkan kembali selama 30 menit. Larutan dituang dalam cetakan polipropilena dan dikeringkan pada suhu 60°C selama 24 jam. Hasil penelitian menunjukkan gliserol meningkatkan transparansi dan elongasi, tetapi mengurangi kuat tarik dan ketahanan air. Penambahan 1% gliserol menghasilkan bioplastik dengan karakteristik terbaik, memenuhi Japanese Industrial Standard. FTIR dan SEM menunjukkan sifat bioplastik yang serupa pada semua perlakuan. Penelitian ini menunjukkan bahwa limbah ekstraksi karagenan K. alvarezii menjanjikan sebagai bahan kemasan dan produksi bioplastik.
Karakterisasi Morfometri dan DNA Barcoding Keong Lola Merah (Rochia nilotica Linnaeus, 1767) dari Kepulauan Kei, Maluku
Authors: Triandiza Teddy , Utami Risnita Tri , Pesilette Rosmi Nuslah 
Published: December 2024

The lola snail (Rochia nilotica) is an herbivorous gastropod that lives in coral reef ecosystems. R. nilotica is an ecologically important species and has high economic value. This study aims to assess morphometric characterization and DNA barcoding. Analysis of growth patterns shows that red lola snails in the Kei Islands show an allometric growth pattern. Analysis of R. nilotica mitochondrial DNA (mtDNA) sequences resulted in 646 base pairs, containing 14 haplotypes with a total of 18 polymorphic sites. The results showed that the genetic diversity of R. nilotica populations in the Kei Islands was very high, namely nucleotide diversity (Pi) of 0.00460 and haplotype diversity (Hd) of 0.9457. The results of phylogenetic tree analysis showed five main clusters, namely four clusters of R. nilotica from the Kei Islands and one cluster of R. nilotica from Moorea Island and New Caledonia. The value of genetic distance between individuals and between R. nilotica populations is very low, namely 0.0026-0.0056 and 0.0034-0.0052. The results of the haplotype net analysis showed that there was haplotype mixing in all R. nilotica populations in the Kei Islands as indicated by the absence of a particular clade. Keong lola merah (Rochia nilotica) merupakan gastropoda herbivora yang hidup di ekosistem terumbu karang. R. nilotica merupakan spesies yang penting secara ekologis dan memiliki nilai ekonomi tinggi. Penelitian ini bertujuan untuk mengkaji karakterisasi morfometri dan DNA barcoding. Analisis pola pertumbuhan menunjukkan keong lola merah di Kepulauan Kei menunjukkan pola pertumbuhan alometrik. Analisis sekuens DNA mitokondria (mtDNA) R. nilotica menghasilkan 646 pasangan basa, yang mengandung 14 haplotipe dengan jumlah total 18 situs polimorfik. Hasil penelitian menunjukkan bahwa keragaman genetik populasi R. nilotica di Kepulauan Kei sangat tinggi, yaitu keragaman nukleotida (Pi) sebesar 0,00460 dan keragaman haplotipe (Hd) sebesar 0,9457. Hasil analisis pohon filogenetik menunjukkan lima kluster utama, yaitu empat kluster R. nilotica asal kepulauan Kei dan satu kluster R. nilotica asal Moorea Island dan New Caledonia. Nilai jarak genetik antar individu dan antara populasi R. nilotica sangat rendah yaitu 0,0026-0,0056 dan 0,0034-0,0052. Hasil analisis jaring haplotipe menunjukkan bahwa terjadi percampuran haplotipe pada seluruh populasi R. nilotica di Kepulauan Kei yang ditunjukkan dengan tidak adanya klade tertentu.
Indeks Ekologi Komunitas Tintinnid (Protozoa:Ciliophora) di Perairan Banggai, Sulawesi Tengah
Authors: Sugiyanto Nenden Rose , Widianingsih Widianingsih , Suryono Chrisna Adhi , Hartati Retno , Endrawati Hadi 
Published: December 2024

There are several groups of organisms in zooplankton, including ciliates (Filum Ciliophora). Ciliates that live in the sea belong to the suborder tintininna or also often referred to as tintinnids. This study aims to determine the type and abundance and analyze the ecological index of the tintinnid community in Banggai Waters, Central Sulawesi. This research was conducted at 35 stations on 1 – 14 September 2022 in the Banggai Waters, Central Sulawesi. The samples were taken by vertical method. The results showed that 9 families, 20 genera, and 35 tintinnid species were identified. The abundance of tintinnids in Banggai Waters has an average of 5763 cells/m3. Furthermore, the distribution pattern of total abundance at each station shows a clustered distribution pattern. The diversity of tintinnid abundance in Banggai Waters has an average of 2.15, classified as moderate. Tintinnid uniformity in Banggai Waters has an average of 0.63 classified as high. The dominance of tintinnids in Banggai Waters has an average of 0.17 classified as low category. The relationship between total abundance and diversity index shows a positive correlation. Meanwhile, the relationship between the abundance and evenness indices and the dominance indices shows a negative correlation. The study's results suggest that the condition of the tintinnid community in Banggai Waters is stable. Filum Ciliophora (Ciliata) termasuk dalam kelompok mikrozooplankton. Ciliata yang hidup di laut termasuk ke dalam subordo Tintininna atau juga sering disebut dengan tintinnid. Penelitian ini bertujuan untuk mengetahui jenis, kelimpahan, dan indeks ekologi dari komunitas tintinnid yang berada di Perairan Banggai, Sulawesi Tengah. Pengambilan sampel dilakukan pada tanggal 1- 14 September 2022 di Perairan Sulawesi Tengah. Sampel mikrozooplankton diambil secara vertikal pada 35 stasiun. Hasil penelitian menunjukkan bahwa ditemukan 9 famili, 20 genus, dan 35 spesies tintinnid yang teridentifikasi. Kelimpahan tintinnid di Perairan Banggai memiliki rata-rata sebesar 5763 sel/m3. Selanjutnya pola sebaran dari kelimpahan total di tiap stasiun menunjukkan pola sebaran mengelompok. Kenekaragaman Kelimpahan tintinnid di Perairan Banggai memiliki rata-rata sebesar 2,15 tergolong kategori sedang. Keseragaman tintinnid di Perairan Banggai memiliki rata-rata sebesar 0,63 tergolong kategori tinggi. . Dominansi tintinnid di Perairan Banggai memiliki rata-rata sebesar 0,17 tergolong kategori rendah. Hubungan anatara kelimpahan total dengan indek keanekaragaman menjukkan korelasi positif. Sedangkan hunbungan antrara kelimpahan dengan indek keseragman dan indek dominansi menjukkan adanya korelasi negatif. Berdasarkan hasil penelitian dapat disimpulkan bahwa kondisi komunitas tintinnid di Perairan Banggai termasuk stabil.
Gebhardt, Bruno: Ein jüdischer Historiker, der mit seinem Handbuch das Geschichtsbild der Deutschen prägte. Ein bio-bibliographischer Beitrag
Authors: Wyrwa Ulrich 
Published: December 2024

Zusammenfassung
Der Abschluss der völlig neu bearbeiteten 10. Auflage des „Gebhardt“ gibt Anlass, einen Blick auf den Namensgeber und Herausgeber der ersten Auflagen, Bruno Gebhardt, zu werfen. Der Aufsatz zeichnet den beruflichen und wissenschaftlichen Lebensweg des 1858 in Krotoschin in der preußischen Provinz Posen geborenen jüdischen Historikers Gebhardt nach. An der Universität Breslau hat er mit einem Stipendium der jüdischen Gemeinde Geschichte studiert und sein Studium 1883 mit Dissertation abgeschlossen. 1887 ging er nach Berlin, wo er an einer Städtischen Realschule unterrichtete. Weiterhin aktiv war Gebhardt auf dem Feld der Wissenschaften. So veröffentlichte er eine große Zahl von Aufsätzen und Rezensionen in mehreren wissenschaftlichen Zeitschriften. Daneben nahm er 1890 die Arbeit an jenem Projekt auf, das ihn berühmt machen sollte, dem „Handbuch der Deutschen Geschichte“. Bald nach dessen Erscheinen legte Gebhardt einen großformatigen, reich illustrierten Band mit Biographien der deutschen Kaiser vor. Es folgte eine für ein breites Publikum bestimmte Deutsche Geschichte im 19. Jahrhundert. Die größte wissenschaftliche Anerkennung aber hatte Bruno Gebhardt seinerzeit mit umfangreichen Studien über Wilhelm von Humboldt gefunden, die ihm auch den Professorentitel einbrachten. Gebhardt ist zwar fünf Jahre nach dem Erscheinen des Handbuchs aus der jüdischen Gemeinde ausgetreten, konvertiert aber ist er nicht. Der Aufsatz arbeitet so die Bedeutung heraus, die ein jüdischer Historiker wie Bruno Gebhardt für das Geschichtsbewusstsein und die historische Bildung in Deutschland erlangen konnte.
SAÚDE E GÊNERO: O ENFRENTAMENTO CITADÍNEO ÀS EPIDEMIAS NA ERA MODERNA LUSITANA E A REPRESENTAÇÃO DO CORPO DA MULHER
Authors: Pizolati Audrei Rodrigo da Conceição 
Published: December 2024

Health and gender: the citizen address in Portugal to epidemics in the modern Lusitanian era and the representation of the woman’s bodyNo intuito de analisar como as epidemias dos séculos XVI e XVII assolaram o Portugal modernista, elencou-se como ferramenta teórica e metodológica os estudos foucaultianos sob a grade analítica da norma e do controle. À vista disso, no enfretamento as epidemias foram postas em práticas medidas de segurança pública visando cerceamento à circulação de indivíduos entre e nas cidades. Em concomitância, o estabelecimento das Santa Casas de Misericórdia almejava a salvação do corpo e da alma, ou seja, os cuidados com a saúde justapostos a fé católica professada pela sociedade e expressa nessas instituições. Nesse processo de cura e de entendimento da doença e do doente, debateu-se os efeitos das pestes no corpo, sobretudo na mulher, alvo de estudos no período. Esse interesse corroborava a tese de uma distinção entre homens e mulheres, mas não pela diferença em si, e sim a partir do aspecto evolutivo. Subentendia-se que a mulher estaria em um estágio anterior à evolução humana, sendo o homem branco o topo da cadeia evolutiva natural – física e cognitivamente. Ao que concerne as epidemias, atualmente, essas questões reverberam de outros modos no presente, em que o cuidado com a fronteira e o embate as epidemias ainda se fazem necessários, especialmente em tempos de Covid-19.Palavras-chave: Controle social; Corpo feminino; Epidemias. Abstract: In order to analyze how the epidemics of the 16th and 17th centuries plagued modernist Portugal, Foucaultian studies were listed as a theoretical and methodological tool under the analytical framework of norm and control. Therefore, in the fight against epidemics, public security measures were put in place to curb the movement of individuals between and in cities. Concomitantly, the implantation of the Santas Casas de Misericórdia aims at the salvation of body and soul, that is, health care juxtaposed with the Catholic faith professed by society and expressed in these institutions. In this process of healing and understanding the disease and the patient, the effects of pests on the body were discussed, especially on women, who were the target of studies in the period. This interest corroborated the thesis of a distinction between men and women, but not for the difference itself, but for the evolutionary aspect. It was understood that the woman would be in a stage prior to human evolution, with the white man being the top of the natural evolutionary chain - physically and cognitively. With regard to epidemics, these issues have repercussions in other ways today, in which care with the border and the fight against epidemics are still necessary, especially in Covid-19.Keywords: Social control; Feminine body; Epidemics.