bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PENGETAHUAN KEBENCANAAN TERHADAP SIKAP KESIAPSIAGAAN DALAM MENGHADAPI BENCANA PADA MAHASISWA PROGRAM STUDI PENDIDIKAN GEOGRAFI UNIVERSITAS KANJURUHAN MALANG
Authors: Kurniawati Dwi , Suwito Suwito 
Published: August 2019

Pengetahuan merupakan faktor utama dan menjadi kunci untuk kesiapsiagaan. Pengetahuan yang dimiliki dapat mempengaruhi sikap dan kepedulian untuk siap siaga dalam mengantisipasi bencana. Pentingnya kesiapsiagaan merupakan salah satu elemen penting dari kegiatan pencegahan pengurangan risiko bencana yang bersifat pro-aktif sebelum terjadinya suatu bencana. Penting bagi mahasiswa program studi pendidikan geografi Universitas Kanjuruhan Malang memiliki pengetahuan kebencanaan serta kesiapan bencana yang baik. Tujuan penelitian ini antara lain: 1) Mengetahui tingkat pengeta-huan kebencanaan pada mahasiswa program studi pendidikan geografi Universitas Kanjuruhan Malang. 2) Mengetahui sikap kesiapsiagaan dalam menghadapi bencana pada mahasiswa program studi pendidikan geografi Universitas Kanjuruhan Malang. 3) Mengetahui pengaruh pengetahuan kebencanaan terhadap sikap kesiapsiagaan dalam menghadapi bencana pada mahasiswa program studi pendidikan geografi Universitas Kanjuruhan Malang. Rancangan penelitian ini menggunakan rancangan deskriptif kuantitatif. Desain penelitian cross sectional, yaitu hanya mengkaji masalah atau keadaan objek pada waktu penelitian berlangsung untuk melihat pengaruh tingkat pengetahuan kebencanaan terhadap sikap kesiapsiagaan mahasiswa. Proses pengumpulan dan pengukuran variable-variabelnya dilakukan pada waktu yang bersamaan. Populasi dalam penelitian ini adalah seluruh mahasiswa Prodi Pendidikan Geografi Universitas Kanjurahan Malang yang berjumlah 178. Teknik sampling dalam penelitian ini adalah Proportional random sampling, yakni sampel diambil 30% dari 178 mahasiswa sehingga diperoleh 53 mahasiswa. Berdasarkan hasil penelitian tingkat pengetahuan kebencanaan mahasiswa berada dikategori tinggi. Sikap kesiapsiagaan mahasiswa dalam menghadapi bencana berada dikategori sangat tinggi. Hasil pengujian hipotesis dengan uji t dan uji koefisien determinasi, maka ada pengaruh positif pengetahuan kebencanaan terhadap sikap kesiapsiagaan mahasiswa dalam menghadapi bencana. Hal ini berarti semakin tinggi pengetahuan kebencanaan maka akan semakin tinggi pula sikap kesiapsiagaan mahasiswa dalam menghadapi bencana.
PENGARUH OBJEK WISATA DANAU KELIMUTU DAN TENUN IKAT TERHADAP KONDISI EKONOMI MASYARAKAT
Authors: Muda Maria Agustina , Suwito Suwito 
Published: August 2019

Danau Kelimutu adalah danau kawah yang terletak di puncak gunung kelimutu tepatnya terletak di Desa Pemo Kabupaten Ende Flores NTT, Indonesia. Salah satu kelebihan dari objek wisata Danau Kelimutu adalah danau kawah dengan memiliki 3 macam warna yaitu merah, biru, dan putih. Objek wisata Danau Kelimutu ini memiliki daya tarik tersendiri yang mampu menarik wisatawan untuk berkunjung yaitu didukung oleh potensi yang lain salah satunya adalah Tenun Ikat. Tujuan penelitian ini adalah Mengetahui pengaruh objek wisata Danau Kelimutu dan Tenun Ikat terhadap kondisi ekonomi masyarakat Desa Pemo Kabupaten Ende. Metode yang digunakan dalam penelitian ini adalah pendekatan kuantitatif dengan variabel bebas yaitu Pengaruh Objek Wisata Danau Kelimutu (X1) dan Tenun Ikat (X2), dan variabel terikatnya adalah Kondisi Ekonomi Masyarakat. Rancangan penelitian ini merupakan analisis regresi linear berganda, untuk mengetahui pengaruh Objek Wisata Danau Kelimutu dan Tenun Ikat terhadap kondisi ekonomi masyarakat. Berdasarkan hasil analisis SPSS 16.0 For Windows terdapat pengaruh yang signifikan antara keberadaan objek wisata Danau Kelimutu (X1) dan Tenun Ikat (X2) terhadap kondisi ekonomi masyarakat (Y). Berdasarkan hasil analisis yang diperoleh menunjukan koefisien regresi yang diperoleh yaitu Y= 13.360 + -0.021X1 + 0.266X2 dengan nilai sebesar 12,5%, dan sisanya (87,5%) dijelaskan atau diberikan oleh variabel-variabel lain yang tidak diteliti dalam penelitian ini. Hal ini menunjukan bahwa keberadaan objek wisata Danau Kelimutu tidak berpengaruh terhadap kondisi ekonomi masyarakat dan Tenun Ikat berpengaruh terhadap kondisi ekonomi masyarakat. Saran dalam penelitian ini diharapkan menjadi bahan masukan untuk seluruh masyarakat agar lebih memanfaatkan potensi dan keahliannya terlebih dahulu khusus pada sektor pariwisata.
Spatial epidemiology of hemorrhagic fever with renal syndrome and rodent hantavirus infection in Guangzhou city, China: lessons learned from a study with long-term surveillance data
Authors: Chen Dehao , Chen Shouyi , Liang Song , Xu Jianmin , Yang Zhicong , Wei Yuehong 
Published: August 2019

Abstract
Background: Though Guangzhou city is not a region with a high burden of hemorrhagic fever with renal syndrome (HFRS) comparing with other areas in China, outbreaks still occur in the city due to the existence of urban rodents and a large urban population at risk. In this study, descriptive temporal analysis and geographic information system (GIS)-based spatial analysis were performed on reported HFRS cases and rodent surveys with the goals of identifying risk areas for public health interventions and presenting the methods and outcomes of the surveillance that can be studied by similar urban settings.
Methods: Period prevalence and the number of positive cases at different geographical scales of the city during 2008-2016 were calculated and summarized based on HFRS and rodent-borne disease surveillance data. Spatial point pattern analyses were conducted to describe global and local clustering effects of different measurements of human HFRS and rodent hantavirus at old-town and whole-city levels.
Results: Geographical distributions of HFRS cases and traps with hantavirus antibody-carrying rodents from 2008 to 2016 were mapped at the city and old-district levels in the aspect of the crude number of positive cases and period prevalence. The weighted K-function suggested that no global clustering effect existed for both the rodent and human cases in different scales of the city. Using Gi*(d) statistic, 22 significant local clusters of high infection (P<0.05) with different radius were discovered for the human and rodent surveillance data, and a zoonotic link was built based on the overlay of clusters of the two species. Also, the seasonal occurrence of HFRS presented a summer peak in the city.
Conclusion: The applications of descriptive temporal analysis, GIS and spatial point pattern analysis, offer ways to quantify zoonotic hantavirus risks across different times and spatial scales and to further recognize putative environmental determinants potentially influential in increased disease risks. The study also fills information gaps about hantavirus surveillance in the non-endemic region, and the methods used for rodent survey in China for controlling HFRS, which is not well documented.
Polymorphisms rs693421 and rs2499601 at locus 1q43 and their haplotypes are not associated with primary open-angle glaucoma: a case-control study
Authors: Kondkar Altaf A , Azad Taif A. , Sultan Tahira , Al-Mobarak Faisal A. , Kalantan Hatem , Al-Obeidan Saleh A. 
Published: August 2019

Abstract
Objective: The genetic spectrum of primary open-angle glaucoma (POAG) in middle-eastern Saudi's is still elusive. To this end, we investigated an association between rs693421, rs2499601 and their haplotypes at chromosome 1q43 locus with POAG and its clinical phenotypes. Genotyping was performed with TaqMan® assays. Haplotypes and their interaction analysis were carried out by SHEsis and SNPStats online tools.
Results: The minor “T” allele frequency of rs693421 was 0.48 in controls and 0.52 in cases (odds ratio (OR)=1.15, 95% confidence interval (CI)=0.85–1.54, p=0.368). Similarly, for rs2499601, the minor “C” allele frequency was 0.49 in controls as compared to 0.53 in cases (OR=1.19, 95% CI=0.89–1.60, p=0.236). Besides, genotype distribution for both these polymorphisms was also not significant in additive, dominant and recessive models. rs693421 and rs2499601, showed significant linkage disequilibrium (D’ statistics = 0.69, p<0.001) but haplotype association was non-significant (p=0.698). The significance did not vary after adjustment to age and sex. No significant genotype association was observed with intraocular pressure, cup/disc ratio and number of anti-glaucoma medication in POAG group. Furthermore, age, sex and genotypes did not contribute any significant risk of POAG in regression analysis. We report no association between rs693421, rs2499601 and their haplotypes with POAG and related phenotypes.
A Complex Teamwork Intervention in a Surgical Ward in Norway
Authors: Aaberg Oddveig Reiersdal , Hall-Lord Marie Louise , Husebø Sissel Iren Eikeland , Ballangrud Randi 
Published: August 2019

Abstract
Objectives: Interprofessional team training has a positive impact on team behavior and patient safety culture. The objective of the study was to explore the impact of an interprofessional teamwork intervention in a surgical ward on structure, process and outcome. In this paper, the implementation of the teamwork intervention is reported to expand the understanding of the future evaluation results of this study.
Results: The evidence-based Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS) program in the ward was implemented in three phases according to the program’s implementation plan, which are built on Kotter’s organizational change model. In the first phase, a project group with the leaders and researchers was established and information about the project was given to all health care personnel in the ward. The second phase comprised six hours interprofessional team training for all frontline health care personnel followed by 12 months implementation of TeamSTEPPS tools and strategies. In the third phase, the implementation of the tools and strategies continued, and refresher training was conducted.

Trial registration: Trial registration number (TRN) is ISRCTN13997367. The study was registered retrospectively with registration date May 30, 2017.

Keywords: Implementation, Inter-professional, Intervention, Patient safety, Surgical ward, Team training, TeamSTEPPS
A meta-analysis of comparison of proximal gastrectomy with double-tract reconstruction and total gastrectomy for proximal early gastric cancer
Authors: Li Shengnan , Gu Lihu , Shen Zefeng , Mao Danyi , Khadaroo Parikshit Asutosh , Su Hui 
Published: August 2019

Abstract
Background

In theory, proximal gastrectomy with double-tract reconstruction (PG-DT) was superior to total gastrectomy (TG) in hematologic and nutritional outcomes. However, its clinical effects in proximal early gastric cancer (EGC) have been controversial.

Methods

The purpose of this study was to investigate the outcomes of laparoscopic proximal gastrectomy with double-tract reconstruction (LPG-DT) for proximal EGC. For this systematic review and meta-analysis, we searched for articles published before December of 2018 in the following databases: PubMed, Web of Science, EBSCO, Medline, and Cochrane Library.

Results

The results showed no significant difference in the anastomotic stenosis (OR=0.91, 95%CI=0.33-2.50, p=0.85) and reflux esophagitis (OR=1.87, 95%CI=0.62-5.65, p=0.27) between LPG-DT and laparoscopic total gastrectomy (LTG). The vitamin B12 supplementation rate in the LPG-DT group was lower than the LTG group (OR=0.06, 95%Cl=0.01-0.59, p=0.02).

Conclusions

Due to comparable clinical effect, PG-DT is comparable to TG for patients with proximal EGC. In addition, LPG-DT not only appears superior to TG in terms of preventing vitamin B12 deficiency, but also does not increase the risk of anastomotic stricture and reflux esophagitis.
Comparative functional genomics analysis of cytochrome P450 gene superfamily in wheat and maize
Authors: wei kaifa , Li YiXuan 
Published: August 2019

Abstract
The cytochrome P450s (CYP450s) as the largest enzyme family of plant metabolism participate in various physiological processes, whereas no study has demonstrated interest in comprehensive comparison of the genes in wheat and maize. Genome-wide survey, characterization and comparison of wheat and maize CYP450 gene superfamily are useful for genetic manipulation of the Gramineae crops.

Results

In total, 1285 and 263 full-length CYP450s were identified in wheat and maize, respectively. According to standard nomenclature, wheat CYP450s (TaCYP450s) were categorized into 45 families, while maize CYP450s (ZmCYP450s) into 43 families. Of maize CYP450s, there are 108 duplicated gene pairs and 134 genes had their syntenic counterparts in rice genome, and a total of 140 duplication events were predicted in wheat CYP450s. Functional divergence analysis at the amino acid level of representative clans CYP51, CYP74 and CYP97 in wheat, maize and rice identified some critical amino acid sites that are responsible for functional divergence of a gene family. Expression profiles of Ta-, ZmCYP450s were investigated using RNA-seq data, and we found the majority of them showed tissue-specific expression patterns such as TaCYP51H39_5B in root; TaCYP74A98_4A in leaf at cotyledon emergence stage (LCE); TaCYP71C162_5A in fruit at whole plant fruit ripening stage (FR); ZmCYP707A5 in root; ZmCYP76B18 in tassel; ZmCYP78A130 in embryo. Under water-deficit condition, 82 and 39 significantly differentially expressed CYP450s were respectively detected in wheat and maize like TaCYP71Y18_1D, TaCYP707A5_6A, TaCYP71R11_1A, TaCYP97B4_6D, ZmCYP81N4, ZmCYP81A1 and ZmCYP71C62, of which TaCYP71Y18_1D and ZmCYP81N4 were the genes most highly induced by drought treatment. Fourteen CYP450s were selected to validate their expression level through qRT-PCR. In total, 477 TaCYP450s were distributed in 22 co-expression modules, and some co-expressed genes that likely take part in the same biochemical pathway were identified. For instance, the expression of TaCYP74A98_4D was highly correlated with TaLOX9, TaLOX36, TaLOX39, TaLOX44 and TaOPR8, and all of them may be involved in jasmonate (JA) biosynthesis. TaCYP73A201_3A showed coexpression with TaPAL1.25, TaCCoAOMT1.2, TaCOMT.1, TaCCR1.6 and TaLAC5, which probably act in the wheat stem and/or root lignin synthesis pathway.
Diagnostic System in Mono Frequency Electrical Impedance Mammography (EIM) in Breast Cancer Screening.
Authors: Ortiz Blanca Murillo , Ramirez Abraham Hernández , Villanueva Talia Rivera , García David Suárez , Pérez Mario Murguía , Penin Allyson Rodríguez , Coripuna Rosario Romero , Partida Xyomara López 
Published: August 2019

Abstract
Background Some evidence has been found that malignant breast tumors have lower electrical impedance than surrounding normal tissues. Electrical impedance could be used as an indicator for breast cancer detection.
Methods Is a prospective, cross-sectional epidemiological observational study of serial screening. The women were invited to participate and signed their consent letter. The purpose of our study was to analyze the sensitivity and specificity of electrical impedance mammography (EIM) and its implementation for the differential diagnosis of pathological lesions of the breast, either alone or in combination with mammography / ultrasound, in 1200 women between 25 to 70 years old.
Results We found a sensitivity of 85 % and a specificity of 96 %, the positive predictive value was 12% and 99% negative predictive value. Seven biopsy confirmed cancers. Significant correlation between electrical conductivity index and Body mass index (BMI) (p<0.05) and patient's age was observed (p=0.01). We also observed that the average of the conductivity distribution is increasing according to the age group (p <0.01). We used chi-squared test to assess for interactions between percent density mammary and BMI (normal <25 kg/m2 (n= 310), overweight 25-29.9 kg/m2 (n= 418) and obese ≥ 30 (n=437) (p<0.05). The patients with a diagnosis of mammary carcinoma had a BMI of 35.51 kg / m2.
Conclusions Our study showed that the sensitivity and specificity of Mono Frequency Electrical Impedance Mammography (EIM) has 85% and 96% respectively. These results suggest that breast electroimpedance can be used in women with obesity and dense breasts since these factors generate an effect that leads to a high rate of cancers at intervals, especially in young women.
Keywords: Breast cancer, Screening, Frequency Electrical Impedance.
The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice
Authors: Xu Hong , Shi Yu , Yao Wen , Sun Li , Li Guomin , Ding peipei , Hu Weiguo , Liu Haimei 
Published: August 2019

Abstract
Background: Inhibition of complement inhibition is recognized as a promising treatment for lupus. The safety and efficacy of a novel complement inhibitor, CRIg/FH, in the treatment of lupus nephritis in a mouse model of MRL/ lpr were observed.
Method: 12 weeks old MRL/lpr female mice were randomly divided into treatment group and control group. 8 MRL/ lpr mice in every treatment group were intraperitoneally injected with complement inhibitor CRIg/FH at 10mg/kg(A1), 5mg/kg(A2) and 2mg/kg(A3). Mice in control group B1 were intraperitoneally injected with 2ml normal saline. Mice in control group B2 received daily steroid gavage. 8 C57BL/6J mice in B3 group were normal control group. Plasma biochemical indexes and immunological indexes were measured at 16 and 20 weeks. Renal histopathological examination was performed.
Result: Complement inhibitor CRIg/FH reduces the proteinuria of MRL/lpr mice and prevented renal failure. The proteinuria level of group A1-A3 were significantly lower than those in the group B1 and B2(P<0.05). At 20 weeks serum creatinine levels of group A1, A2 and A3 were significantly lower than those in the control group B1 (P<0.05). In the treatment group A1, A2 and A3, the deposition of complement MAC, C1q and C3d was reduced compared with control group B1. Complement inhibitor CRIg/FH reduced complement activation and autoantibody production in MRL/LPR mice: At 20 weeks the blood levels of C3, C4 and C5a in group A1, A2 and A3 were significantly higher than those in the control group B1 (P<0.05). Blood anti-double-stranded DNA levels of group A1, A2 and A3 were also significantly lower than those in the control group B1 at 20 weeks. (P<0.05).
Conclusion: CRIg/FH has a better therapeutic effect on lupus nephritis in MRL/lpr mice. The protective effect in lupus nephritis is manifested in many aspects, including reducing proteinuria, decreasing serum creatinine and urea nitrogen levels, and reducing renal tubular inflammation. Our findings confirm that complement inhibitors can treat lupus nephritis in a dose-dependent manner. Its application prospect in patients with lupus is expected.
Intrathecal morphine is associated with less delirium following hip fracture surgery; a register study
Authors: Koning Mark Vincent , Sijp Max P.L. van der , Stolker Robert Jan , Niggebrugge Arthur H.P. 
Published: August 2019

Abstract
Purpose

Delirium is a common complication after proximal femoral fracture surgery and contributing factors are pain and opioid consumption. The administration of intrathecal morphine may decrease these factors postoperatively and potentially decrease delirium. The aim of this research is to study the association between the use of intrathecal morphine and the occurrence of delirium.

Methods

A retrospective analysis of a register kept in a non-academic hospital in the Netherlands was performed. The register contained data of all patients with proximal femur fractures that were surgically treated with osteosynthesis or prothesis. Patients receiving spinal anesthesia with local anesthetics (SA-group) were compared with patients receiving spinal anesthesia with the addition of intrathecal morphine (SIM-group). The administration of either SA or SIM was based on the preference of the anesthesiologist. Primary outcome was the incidence of delirium, as defined by the DSM-V classification. Both univariate and multivariate analysis were performed.

Results

The SA-group consisted of 451 patients and 34 patients were included in the SIM-group. Delirium occurred in 19.7% in the SA-group versus 5.9% in the SIM-group (p=0.046). This association remained significant after correction in multivariate analysis (OR of delirium in the SA group, 95% CI: 1.062 – 21.006, p=0.041). Additionally, multivariate analysis revealed that age, gender, preoperative cognitive impairment and fracture treatment (osteosynthesis or prosthesis) were independently associated with delirium .

Conclusion

This retrospective study found an independent association between the use of intrathecal morphine and a lower incidence of delirium. This clinically relevant decrease in delirium should be studied in a prospective randomised study.
Low red/far-red ratio as a signal promotes carbon assimilation of soybean seedlings by increasing the photosynthetic capacity
Authors: Yang Feng , Liu Qinlin , Cheng Yajiao , Feng Lingyang , Wu Xiaoling , Fan Yuanfang , Raza Muhammad Ali , Wang Xiaochun , Yong Taiwen , Liu Weiguo , Liu Jiang , Du Junbo , Shu Kai , Yang Wenyu 
Published: August 2019

Abstract
Background

Shading includes low light intensity and varying quality. However, a low red/far-red (R/Fr) ratio of light is a signal that affects plant growth in intercropping and close- planting systems. Thus, the low R/Fr ratio uncoupling from shading conditions was assessed to identify the effect of light quality on photosynthesis and CO2 assimilation. Soybean plants were grown in a growth chamber with natural solar radiation under four treatments, that is, normal (N, sunlight), N+Fr, Low (L) +Fr, and L light.

Results

Results showed that low R/Fr ratio significantly increased the total biomass, the ratio of the cross-sectional area of all starch to that of chloroplasts, starch and sucrose contents, net photosynthetic rate, and chlorophyll content compared with normal R/Fr ratio under the same light intensity condition (P < 0.05). Proteomic analysis of soybean leaves under different treatments was performed to quantify the changes in photosynthesis and CO2 assimilation in the chloroplast. Among the 7834 proteins quantified, 12 showed a > 1.5-fold change in abundance, of which 1 was related to porphyrin and chlorophyll metabolism, 2 were involved in photosystem I (PS I), 4 were associated with PS II, 3 proteins participated in photosynthetic electron transport, and 2 were involved in starch and sucrose metabolism. The dynamic change in these proteins indicates that photosynthesis and CO2 assimilation were maintained in the L treatment by up-regulating the component protein levels compared with those in N treatment. Although low R/Fr ratio increased the photosynthetic CO2 assimilation parameters, the differences in most protein expression levels in N+Fr and L+Fr treatments compared with those in N treatment were insignificant. Similar trends were found in gene expression through quantitative reverse transcription polymerase chain reaction excluding the gene expression of sucrose synthase possible because light environment is one of the factors affecting carbon assimilation.

Conclusions

These results implied that low R/Fr ratio (high Fr light) increased the photosynthetic CO2 assimilation in the same light intensity by improving the photosynthetic efficiency of the photosystems.