bluuebunny/crossref_metadata_2025_split huggingface dataset:
HFF-DeepSpace Photometric Catalogs of the 12 Hubble Frontier Fields, Clusters, and Parallels: Photometry, Photometric Redshifts, and Stellar Masses
Authors: Shipley Heath V. , Lange-Vagle Daniel , Marchesini Danilo , Brammer Gabriel B. , Ferrarese Laura , Stefanon Mauro , Kado-Fong Erin , Whitaker Katherine E. , Oesch Pascal A. , Feinstein Adina D. , Labbé Ivo , Lundgren Britt , Martis Nicholas , Muzzin Adam , Nedkova Kalina , Skelton Rosalind , van der Wel Arjen 
Published: March 2018

Abstract
We present Hubble multi-wavelength photometric catalogs, including (up to) 17 filters with the Advanced Camera for Surveys and Wide Field Camera 3 from the ultra-violet to near-infrared for the Hubble Frontier Fields and associated parallels. We have constructed homogeneous photometric catalogs for all six clusters and their parallels. To further expand these data catalogs, we have added ultra-deep K

S
-band imaging at 2.2 μm from the Very Large Telescope HAWK-I and Keck-I MOSFIRE instruments. We also add post-cryogenic Spitzer imaging at 3.6 and 4.5 μm with the Infrared Array Camera (IRAC), as well as archival IRAC 5.8 and 8.0 μm imaging when available. We introduce the public release of the multi-wavelength (0.2–8 μm) photometric catalogs, and we describe the unique steps applied for the construction of these catalogs. Particular emphasis is given to the source detection band, the contamination of light from the bright cluster galaxies (bCGs), and intra-cluster light (ICL). In addition to the photometric catalogs, we provide catalogs of photometric redshifts and stellar population properties. Furthermore, this includes all the images used in the construction of the catalogs, including the combined models of bCGs and ICL, the residual images, segmentation maps, and more. These catalogs are a robust data set of the Hubble Frontier Fields and will be an important aid in designing future surveys, as well as planning follow-up programs with current and future observatories to answer key questions remaining about first light, reionization, the assembly of galaxies, and many more topics, most notably by identifying high-redshift sources to target.
Les espaces de discussion : un vecteur de régulation des paradoxes de la Nouvelle Gestion Publique ?
Authors: Bellini Stéphane , Dreveton Benjamin , Grimand Amaury , Oiry Ewan 
Published: March 2018

Les espaces de discussion permettent-ils de réguler les paradoxes de la Nouvelle Gestion Publique (NGP) ? A partir des années 1990, pour tenter de répondre aux critiques classiques adressées aux organisations publiques, la Nouvelle Gestion Publique a impulsé une réforme profonde de ces organisations dans les pays occidentaux. Elle a toutefois créé de nombreux paradoxes sur ce qu’est la performance, la culture ou même la légitimité dans les organisations publiques. Cet article défend l’idée que les « espaces de discussion » sont, pour partie, en mesure de réguler ces paradoxes. Il présente l’étude du cas d’un organisme de formation public. Les résultats montrent que la NGP crée des paradoxes particulièrement forts dans cette organisation et que les espaces de discussion qui existent permettent de réguler partiellement ces paradoxes. Nos résultats mettent en particulier en évidence le rôle que les outils de gestion jouent dans cette régulation. Toutefois, ils soulignent aussi la fragilité de cette régulation et sa difficulté à diffuser ses effets dans l’ensemble de l’organisation tant qu’elle n’est pas soutenue par la direction générale. Ces résultats permettent d’enrichir la littérature existante sur les paradoxes produits par la NGP, sur le rôle des outils de gestion dans le fonctionnement des espaces de discussion et sur la capacité des espaces de discussion à réguler certains paradoxes de la NGP.
Stratégie et liberté d’action
Authors: Desportes Vincent 
Published: March 2018

Préserver, accroître sa liberté de décider et de faire : c’est le cœur de la stratégie, art de l’agir. Les degrés de liberté d’action constituent une véritable monnaie stratégique, qui se réduit ou croît au fil de la relation avec l’adversaire. Cette monnaie doit être dépensée, l’abstention diminuant la capacité à agir ; mais elle n’existe que par les moyens concrets dont dispose le stratège. Cette liberté d’action est centrale à tous niveaux des stratégies, et pour toutes les stratégies.
Maurice Reuchlin et son histoire de la psychologie
Authors: Nicolas Serge 
Published: March 2018

L’article traite de l’apport de Reuchlin en histoire de la psychologie. L’analyse a porté sur deux de ses principaux écrits : 1) son ouvrage de 1957 sur l’histoire de la psychologie, qui eut de nombreuses rééditions jusqu’en 2012 ; 2) son article sur l’histoire de la psychologie française publié en anglais en 1965. On y montre que Reuchlin a privilégié une histoire objective, mais très personnelle de la psychologie. L’histoire de la psychologie qu’il a proposée est une histoire sous-disciplinaire d’orientation très pédagogique mettant l’accent sur l’orientation scientifique de la discipline. On note cependant beaucoup de manques et des distorsions qui l’ont conduit notamment à sous-estimer l’apport de Binet à la psychologie, alors qu’il s’agit du psychologue français encore le plus connu au monde.
Vicariances : la flexibilité du vivant
Authors: Ohlmann Théophile 
Published: March 2018

Les processus vicariants différentiels proposés par Maurice Reuchlin en 1978 se caractérisent par le fait que face à un problème donné, chaque individu disposerait de plusieurs processus redondants. L’évocabilité de chacun de ces processus serait variable d’un individu à l’autre, mais aussi et surtout d’une situation à l’autre. Après les avoir décrits et positionnés dans le cadre des travaux contemporains, leur dynamique, liée à la variabilité intra-individuelle, est développée à partir d’exemples empruntés aux comportements spatiaux, à la neuropathologie et au développement cognitif. Dans une perspective évolutionniste, la convergence entre les vicariances et les théories neutralistes est rappelée.
Discovery and Analysis of Invertebrate IgVJ-C2 Structure from Amphioxus Provides Insight into the Evolution of the Ig Superfamily
Authors: Chen Rong , Zhang Lijie , Qi Jianxun , Zhang Nianzhi , Zhang Ling , Yao Shugang , Wu Yanan , Jiang Bo , Wang Zhenbao , Yuan Hongyu , Zhang Qiujin , Xia Chun 
Published: March 2018

Abstract
The emergence of adaptive immunity in jawed vertebrates depended on the appearance of variable immune receptors, BCRs and TCRs, which exhibit variable-J–constant (VJ-C)–type Ig superfamily folds. Hitherto, however, the structures of IgV-J-IgC–type molecules had never been characterized in invertebrates, leaving the origin of BCR/TCR-type molecules unknown. Using x-ray crystallography, the structure of a VJ-C2 molecule, named AmpIgVJ-C2, was determined in amphioxus (Branchiostoma floridae). The first domain shows typical V folding, including the hydrophobic core, CDR analogs, and eight conserved residues. The second domain is a C2-type Ig superfamily domain, as defined by its short length and the absence of β-strand D- and C1-typical motifs. AmpIgVJ-C2 molecules form homodimers, using “three-layer packing dimerization,” as described for TCRs and BCRs. The AmpIgVJ-C2 V domain harbors a diglycine motif in β-strand G and forms a β-bulge structure participating in V–V intermolecular interaction. By immunohistochemistry, AmpIgVJ-C2 molecules were primarily found in mucosal tissues, whereas PCR and sequence analysis indicated considerable genetic variation at the single-gene level; these findings would be consistent with an immune function and a basic ability to adapt to binding different immune targets. Our results show a BCR/TCR-ancestral like molecule in amphioxus and help us to understand the evolution of the adaptive immune system.
miR-130a and miR-212 Disrupt the Intestinal Epithelial Barrier through Modulation of PPARγ and Occludin Expression in Chronic Simian Immunodeficiency Virus–Infected Rhesus Macaques
Authors: Kumar Vinay , Mansfield Joshua , Fan Rong , MacLean Andrew , Li Jian , Mohan Mahesh 
Published: March 2018

Abstract
Intestinal epithelial barrier dysfunction is a well-known sequela of HIV/SIV infection that persists despite antiretroviral therapy. Although inflammation is a triggering factor, the underlying molecular mechanisms remain unknown. Emerging evidence suggests that epithelial barrier function is epigenetically regulated by inflammation-induced microRNAs (miRNAs). Accordingly, we profiled and characterized miRNA/mRNA expression exclusively in colonic epithelium and identified 46 differentially expressed miRNAs (20 upregulated and 26 downregulated) in chronically SIV-infected rhesus macaques (Macaca mulatta). We bioinformatically crossed the predicted miRNA targets to transcriptomic data and characterized miR-130a and miR-212 as both were predicted to interact with critical epithelial barrier–associated genes. Next, we characterized peroxisome proliferator–activated receptor γ (PPARγ) and occludin (OCLN), predicted targets of miR-130a and miR-212, respectively, as their downregulation has been strongly linked to epithelial barrier disruption and dysbiosis. Immunofluorescence, luciferase reporter, and overexpression studies confirmed the ability of miR-130a and miR-212 to decrease protein expression of PPARγ and OCLN, respectively, and reduce transepithelial electrical resistance. Because Δ-9-tetrahydrocannabinol exerted protective effects in the intestine in our previous studies, we successfully used it to reverse miR-130a– and miR-212–mediated reduction in transepithelial electrical resistance. Finally, ex vivo Δ-9-tetrahydrocannabinol treatment of colon tissue from chronically SIV-infected rhesus macaques significantly increased PPARγ expression. Our findings suggest that dysregulated miR-130a and miR-212 expression in colonic epithelium during chronic HIV/SIV infection can facilitate epithelial barrier disruption by downregulating OCLN and PPARγ expression. Most importantly, our results highlight the beneficial effects of cannabinoids on epithelial barrier function in not just HIV/SIV but potentially other chronic intestinal inflammatory diseases.
Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation
Authors: Bhatt Brinda , Zeng Peng , Zhu Huabin , Sivaprakasam Sathish , Li Siyi , Xiao Haiyan , Dong Lixin , Shiao Pamela , Kolhe Ravindra , Patel Nikhil , Li Honglin , Levy-Bercowski Daniel , Ganapathy Vadivel , Singh Nagendra 
Published: March 2018

Abstract
A set of coordinated interactions between gut microbiota and the immune cells surveilling the intestine play a key role in shaping local immune responses and intestinal health. Gpr109a is a G protein–coupled receptor expressed at a very high level on innate immune cells and previously shown to play a key role in the induction of colonic regulatory T cells. In this study, we show that Gpr109a−/−Rag1−/− mice exhibit spontaneous rectal prolapse and colonic inflammation, characterized by the presence of an elevated number of IL-17–producing Rorγt+ innate lymphoid cells (ILCs; ILC3). Genetic deletion of Rorγt alleviated the spontaneous colonic inflammation in Gpr109a−/−Rag1−/− mice. Gpr109a-deficient colonic dendritic cells produce higher amounts of IL-23 and thereby promote ILC3. Moreover, the depletion of gut microbiota by antibiotics treatment decreased IL-23 production, ILC3, and colonic inflammation in Gpr109a−/−Rag1−/− mice. The ceca of Gpr109a−/−Rag1−/− mice showed significantly increased colonization by members of Bacteroidaceae, Porphyromonadaceae, Prevotellaceae, Streptococcaceae, Christensenellaceae, and Mogibacteriaceae, as well as IBD-associated microbiota such as Enterobacteriaceae and Mycoplasmataceae, compared with Rag1−/− mice, housed in a facility positive for Helicobacter and murine norovirus. Niacin, a Gpr109a agonist, suppressed both IL-23 production by colonic DCs and ILC3 number in a Gpr109a-dependent manner. Collectively, our data present a model suggesting that targeting Gpr109a will be potentially beneficial in the suppression of IL-23–mediated immunopathologies.
Provision of antiretroviral therapy for children in Nelson Mandela Bay: Health care professionals’ challenges
Authors: Williams Margaret , Van Rooyen Dalena R.M. , Ricks Esmeralda J. 
Published: March 2018

Background: The human immunodeficiency virus and/or acquired immune deficiency syndrome (HIV/AIDS) pandemic continues to increase in prevalence worldwide, particularly in South Africa, and includes the often overlooked paediatric population. The provision of paediatric antiretroviral treatment (ART) is as essential for children as for adults, and has numerous obstacles, not least of which is lack of decentralisation of facilities to provide essential treatment. Optimising ART, care and support for HIV-positive children, and their caregivers, at public sector primary health care (PHC) clinics is crucial to improve morbidity and mortality rates in children.Aim: To explore the experiences of health care professionals regarding the provision of ART for children at PHC clinics.Setting: The study was conducted in six PHC clinics in Nelson Mandela Bay Health District, Eastern Cape, South Africa.Methodology: The researchers used a qualitative, explorative, descriptive and contextual research design with in-depth interviews. We used non-probability purposive sampling. Data collected were thematically analysed using Creswell’s data analysis spiral. We used Lincoln and Guba’s model to ensure trustworthiness. Ethical standards were applied.Results: Health care professionals experienced numerous challenges, such as lack of resources, need for training, mentoring and debriefing, all related to providing decentralised ART for HIV-positive children at the PHC level.Conclusion: Capacitation of the health care system, integration of services, competent management and visionary leadership to invoke a collaborative interdisciplinary team approach is required to ensure that HIV is treated as a chronic disease at the PHC clinic level.
Ergonomia Organizacional para a identificação do estado da Casa de Massas do Rio Saltinho: por uma abordagem sistêmica
Authors: Ferreira Alais Souza , Ourives Eliete Auxiliadora Assunção , Figueiredo Luiz Fernando Gonçalves de , Merino Eugenio Andrés Díaz 
Published: March 2018

A ergonomia é a ciência do trabalho orientada para uma abordagem sistêmica de todos os aspectos da atividade humana. Esta ciência busca analisar a adequação do trabalho e ambiente em que as atividades são executadas ao ser humano. Seu objetivo é a satisfação e conforto dos indivíduos, e a garantia que a prática laboral e o uso de equipamentos não causem problemas a saúde do usuário. Dentre os domínios de especialização, o foco deste artigo está na ergonomia organizacional, também chamada de macroergonomia, que é a otimização dos sistemas sociotécnicos, com a inclusão das estruturas organizacionais, políticas e processos. Dessa forma, entende-se o processo como sendo uma abordagem sistêmica, ou seja, o estudo holístico dos sistemas de forma a envolver as suas principais interdependências, pois cada um dos elementos, ao serem reunidos para construir uma unidade funcional maior, desenvolvem qualidades que não se encontram em seus componentes isolados. Este artigo visa estudar a abordagem sistêmica do design na ergonomia organizacional no caso da Casa de Massas do Rio Saltinho – localizada em Chapadão do Lageado, Santa Catariana, Brasil. Para isso é necessário compreender o cenário da ergonomia organizacional da Casa de Massas, por meio da análise de observações e elicitação de vídeos e fotografias, visando a conscientização sistêmica da existência de problemas decorrentes da ausência de ergonomia. Para alcançá-lo é necessário: fazer um levantamento bibliográfico sobre a organizacão do trabalho; observar a linha de processamento, espaco físico e disposicão dos equipamentos; propor diretrizes visando melhorar o ambiente físico juntamente com os demais sistemas sóciotécnicos. A pesquisa classifica-se como exploratória, qualitativa, bibliográfica e documental. A amostra é constituída pela empresa Casa das Massas do Rio Saltinho, selecionada por critério amostral não probabilístico por conveniência em relação ao acesso devido à parceria estabelecida entre a prefeitura de Chapadão do Lageado, a Associação de Micro e Pequenas Empresas (AMPE) e o Núcleo de Abordagem Sistêmica do Design (NASDesign, UFSC). Os dados foram tratados por meio da análise documental constituída por elicitação fotográfica e de vídeo coletados pelo NASDesign em junho de 2014. Os resultados possibilitaram a compreensão do cenário da ergonomia organizacional da casa de massas, e o estabelecimento de diretrizes para o aprimoramento das estruturas organizacionais e do processo de produção. Isto contribui para o bem estar das colaboradoras no ambiente de trabalho, o crescimento empresarial da Casa de Massas e para o estabelecimento de um ambiente de trabalho mais cooperativo e motivador. Palavras-chave: ergonomia organizacional, abordagem Sistêmica, casa de massas do Rio Saltinho.
Non-methane organic gas emissions from biomass burning: identification, quantification, and emission factors from PTR-ToF during the FIREX 2016 laboratory experiment
Authors: Koss Abigail R. , Sekimoto Kanako , Gilman Jessica B. , Selimovic Vanessa , Coggon Matthew M. , Zarzana Kyle J. , Yuan Bin , Lerner Brian M. , Brown Steven S. , Jimenez Jose L. , Krechmer Jordan , Roberts James M. , Warneke Carsten , Yokelson Robert J. , de Gouw Joost 
Published: March 2018

Abstract. Volatile and intermediate-volatility non-methane organic gases (NMOGs) released from biomass burning were measured during
laboratory-simulated wildfires by proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF). We identified NMOG
contributors to more than 150 PTR ion masses using gas chromatography (GC) pre-separation with electron ionization,
H3O+ chemical ionization, and NO+ chemical ionization, an extensive literature review, and
time series correlation, providing higher certainty for ion identifications than has been previously available. Our
interpretation of the PTR-ToF mass spectrum accounts for nearly 90 % of NMOG mass detected by PTR-ToF across all fuel
types. The relative contributions of different NMOGs to individual exact ion masses are mostly similar across many fires
and fuel types. The PTR-ToF measurements are compared to corresponding measurements from open-path Fourier transform
infrared spectroscopy (OP-FTIR), broadband cavity-enhanced spectroscopy (ACES), and iodide ion chemical ionization mass
spectrometry (I− CIMS) where possible. The majority of comparisons have slopes near 1 and values of the linear
correlation coefficient, R2, of > 0.8, including compounds that are not frequently reported by PTR-MS such as
ammonia, hydrogen cyanide (HCN), nitrous acid (HONO), and propene. The exceptions include methylglyoxal and compounds that
are known to be difficult to measure with one or more of the deployed instruments. The fire-integrated emission ratios to
CO and emission factors of NMOGs from 18 fuel types are provided. Finally, we provide an overview of the chemical
characteristics of detected species. Non-aromatic oxygenated compounds are the most abundant. Furans and aromatics, while
less abundant, comprise a large portion of the OH reactivity. The OH reactivity, its major contributors, and the
volatility distribution of emissions can change considerably over the course of a fire.
From engineering hydrology to Earth system science: milestones in the transformation of hydrologic science
Authors: Sivapalan Murugesu 
Published: March 2018

Abstract. Hydrology has undergone almost transformative changes over the past 50 years. Huge strides have been made in the transition from early empirical approaches to rigorous approaches based on the fluid mechanics of water movement on and below the land surface. However, progress has been hampered by problems posed by the presence of heterogeneity, including subsurface heterogeneity present at all scales. The inability to measure or map the heterogeneity everywhere prevented the development of balance equations and associated closure relations at the scales of interest, and has led to the virtual impasse we are presently in, in terms of development of physically based models needed for hydrologic predictions. An alternative to the mapping of heterogeneity everywhere is a new Earth system science view, which sees the heterogeneity as the end result of co-evolutionary hydrological, geomorphological, ecological, and pedological processes, each operating at a different rate, which help to shape the landscapes that we find in nature, including the heterogeneity that we do not readily see. The expectation is that instead of specifying exact details of the heterogeneity in our models, we can replace it (without loss of information) with the ecosystem function that they perform. Guided by this new Earth system science perspective, development of hydrologic science is now addressing new questions using novel holistic co-evolutionary approaches as opposed to the physical, fluid mechanics based reductionist approaches that we inherited from the recent past. In the emergent Anthropocene, the co-evolutionary view has expanded further to involve interactions and feedbacks with human-social processes as well. In this paper, I present my own perspective of key milestones in the transformation of hydrologic science from engineering hydrology to Earth system science, drawn from the work of several students and colleagues of mine, and discuss their implication for hydrologic observations, theory development, and predictions.
A Sensitivity Analysis of ELECTRE Based Stepwise Benchmarking for Policy: the Case of EU Digital Agenda
Authors: Petrović Marijana , Bojković Nataša , Stamenković Mladen , Anić Ivan 
Published: March 2018

Research question: This paper introduces a new parameter for evaluating the sensitivity of development paths in ELECTRE (ELimination Et Choix Traduisant la Realité) based stepwise benchmarking model. Motivation: The aim of the research was to devise a 'path sensitivity coefficient' which measures the sensitivity of a development path depending on parameters set by decision-maker (DM). The need for such measure comes from the fact that the hierarchical pre-order of benchmarking units are affected by the DM's subjective decisions on the threshold for declaring outranking relations among them. This consequently may disrupt the sequence of intermediate benchmarks - transitional targets to be followed on the route to the ultimate policy goals. The proposed approach is an extension of a stepwise benchmarking procedure devised by Petrovic et al. (2014) which evaluates development paths based on their gradualism. Idea: In this paper, we propose to characterize development paths by considering both gradualism and sensitivity to outranking thresholds. The standpoint of our research is that in order to make a reliable final choice the DM should be aware that the most gradual path is not necessary the most stable one. Tools: The proposed 'path sensitivity coefficient' combines four level of uncertainty coming from two threshold values set by DM. The coefficient has a relative nature, it points to the “distance” from the theoretically ideal solution - a path fully indifferent to threshold values. An approach to merge coefficients associated with gradualism and stability is also introduced. Data: To illustrate the proposed approach we applied it in the field of digital transformation of EU countries. We exploited indicators and data from Digital Agenda Scoreboard regarding specific policy goals to be achieved until 2020. Findings: The findings imply that the decision on the most gradual development path should be reconsidered in regards to the influence of model parameters. The final choice depends whether DM’s prefers the smoothness of the path or the overall stability in terms of underlying partial preorder. Contribution: This work contributes to the existing ELECTRE-based stepwise benchmarking by reducing the uncertainty coming from subjective parameterization and allows the DM to be more confident in the final path selection.