bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mood and Syntactic Choices in Shakespeare’s Julius Caesar: Implications for The Language Teachers
Authors: Owolewa Olusegun , Jimoh Rafiu 
Published: April 2018

<p>Correct verbal identification of different mood system has been a source of concern to teachers of English as a Second Language in Nigeria. Classroom efforts are mostly geared towards recognition of this concept, usually, in abstract and without connection to functional usage. Studies by scholars identify great difficulty in recognition of the verbal elements in sentence conveying the mood. However, such work never establishes a correlation between correct identification of mood and semantic interpretation. The purpose of this study is to establish the syntactic choices of the verbal elements in <em>Julius Caesar </em>and how they have helped to depict the mood of the characters in the text. This work relies on Systemic Functional Grammar approach to establish connection of mood to setting, tone and diction. It establishes that Shakespeare unconsciously reflects the mood through the characters use of certain clauses with the view to probably enhance the readers’ understanding of scene of actions in the play. Implications for the language teachers are discussed. </p>
BİST’te İşlem Gören Faktoring Şirketlerinin Mali Yapılarının Çok Ölçütlü Karar Verme Yöntemleri İle Değerlendirilmesi
Authors: Özbek Aşır 
Published: April 2018

Ticaretin
yurt içi ve yurt dışı finansmanında önemli bir rol oynayan faktoring
şirketlerine duyulan ihtiyaç giderek artmaktadır. Faktoring hizmeti almak
isteyen işletmeler için en uygun faktoring şirketini belirlemek, birçok
faktörün dikkate alınması gereken çok ölçütlü karar verme (ÇÖKV) problemi
olarak görülmektedir. Bu nedenle işletmelerin kendi finansman yapısına uygun
faktoring şirketini seçmesi çok önemli hale gelmektedir.

Bu
çalışmada Borsa İstanbul'da (BİST) işlem gören 7 adet faktoring firması 2013-2016
yıllarındaki bilanço ve gelir tabloları dikkate alınarak mali açıdan
değerlendirilmiştir. Veriler, Kamuya Aydınlatma Platformundan (KAP) elde
edilmiştir. Ölçütler, literatür taraması sonucu belirlenmiştir. Şirketlerin değerlendirilmesinde
ÇÖKV yöntemlerinden olan, Step-wise
Weight Assessment Ratio Analysis (SWARA), Additive Ratio Assessment (ARAS),
Multi-Objective Optimization on the basis of Ratio Analysis (MOORA) and Technique for Order of Preference by
Similarity to Ideal Solution (TOPSIS) yöntemleri bütünleşik
olarak kullanılmıştır. 2013-2016 yılları bütüncül olarak değerlendirildiğinde
her üç yönteme göre ilk sırayı YKFKT ve GARFA, son sırayı ise SMRFT şirketinin
aldığı görülmüştür.
Avaliação da eficiência energética e proposta de soluções sustentáveis para o bloco E do Instituto Federal Fluminense Campus Campos Guarus
Authors: Romano de Moraes Araujo Gabriela , Barcellos Marini Guilherme , Rosa Mendes Luiz Fernando , Monteiro Ramalho Alan 
Published: April 2018

O modelo de desenvolvimento utilizado pela sociedade vem amplificando o uso de recursos naturais e, em consequência desse uso desproporcional, há impacto ambiental. Em vista disso, uma das soluções para amenizar os efeitos desse processo é a utilização eficiente desses recursos. Logo, a busca pela sustentabilidade alcançou o ramo da construção civil, por consequência estabelecendo metas para a eficiência energética. Este trabalho tem como objetivo avaliar a eficiência energética de uma edificação no Instituto Federal Fluminense Campus Campos Guarus. São abordados dois pontos principais: climatização e iluminação, já que se trata dos maiores consumidores de energia elétrica em uma construção. Esse documento utiliza metodologias previstas em Norma Técnica para cálculo da carga térmica e estudo luminotécnico. Dessa forma, são apresentadas soluções para melhorar a eficiência energética e as alternativas para otimização do consumo. Por fim, as propostas para melhoria no consumo são avaliadas pela viabilidade técnica e financeira. Assim, pode-se constatar a eficiência das lâmpadas LED (Diodo Emissor de Luz) em comparação às lâmpadas tubulares fluorescentes, e o superdimensionamento da carga térmica no bloco E.
MIGRATION PROCESSES ON THE PUBLIC LANDS OF THE KUZNETSK REGION IN THE "POST-REFORM" PERIOD
Authors: Karpinets A. Yu. 
Published: April 2018

The current paper features the migratory process on the state lands in the Kuzbass region in the late 1860s – early 1890s. The purpose of the research is to present data on the main problems and features of the resettlement movement in the subregion. The article reviews a significant amount of sources on the matter. An analysis of the statistical and narrative data obtained from the works by A. A.Kauffman, V. N.Sobolev et al allowed the author to make a detailed description of the process in question. No other summary research on Kuzbass history reflects the subject, thus making it possible to use the current results for educational and scientific purposes. The author has allocated and characterized the stages of the migratory process, its dynamics and local features. Up to the middle of the 1880s the settling process was quite active on the territory of the modern Kuzbass, especially in its northwest part, which resulted in dozens of new agricultural settlements populated by farmers from all over the Russian Empire. A new stage of country migrations on the royal lands began in the middle of the 1880s. In 1885 the Ministry of Internal Affairs set up the West Siberian group to deal with the resettlement sites on the local state lands. In 1882 – 1893, 40 new settlements were created on the royal lands of Bogotolsky, Dmitriyevsky, Alchedatsky, Baimsky and Pochitansky areas of the Mariinsky district and the Ishim area of the Tomsk district of the Tomsk province (within the territorial borders of the nowadays Kuzbass), 27 of which were to the southeast from Mariinsk.
Carbon nanotube modified glassy carbon electrode for electrochemical oxidation of alkylphenol ethoxylate
Authors: Patiño Yolanda , Díaz Eva , Lobo-Castañón María Jesús , Ordóñez Salvador 
Published: April 2018

Abstract
Electrochemical oxidation of an emerging pollutant, 2-(4-methylphenoxy)ethanol (MPET), from water has been studied by cyclic voltammetry (CV). Multiwall carbon nanotubes glassy carbon electrodes (MWCNT-GCE) were used as working electrode due to their extraordinary properties. The oxidation process is irreversible, since no reduction peaks were observed in the reverse scan. The electrocatalytic effect of MWCNT was confirmed as the oxidation peak intensity increases in comparison to bare-GCE. The effect of functional groups on MWCNT was also studied by MWCNT functionalized with NH2 (MWCNT-NH2) and COOH (MWCNT-COOH) groups. The oxidation peak current decreases in the following order: MWCNT &gt; MWCNT-NH2 &gt; MWCNT-COOH. Taking into account the normalized peak current, MWCNT-NH2 exhibits the best results due to its strong interaction with MPET. Under optimal conditions (pH = 5.0 and volume of MWCNT = 10 μL), degradation was studied for MWCNT-GCE and MWCNT-NH2-GCE. A complete MPET removal was observed using MWCNT-GCE after four CV cycles, for a volume/area (V/A) ratio equal to 19. In the case of MWCNT-NH2-GCE, the maximum MPET removal was close to 90% for V/A = 37, higher than that obtained for MWCNT-GCE at the same conditions (≈80%). In both cases, no organic by-products were detected.
Emerging Intercultural Identity in the Turkish EFL Context
Authors: Çelik Mehmet 
Published: April 2018

The paper argues that for individuals to develop
intercultural identity, they do not necessarily need to experience
intercultural experiences. A questionnaire devised by the author is
administered to 227 Turkish learners of English aged 19-23. The findings of
self-reported responses to a 37-item questionnaire as well as the qualitative
data reveal that learners feel they have a slightly different identity and that
English is an asset, a passport to a world of new experiences in socialization
and cross-cultural communication. The
paper concludes that it is legitimate to speak of intercultural identity in the
absence of direct contact with L2 community.
A Potential Therapeutic Target RNA-binding Protein, Arid5a for the Treatment of Inflammatory Disease Associated with Aberrant Cytokine Expression
Authors: Masuda Kazuya , Kishimoto Tadamitsu 
Published: April 2018

Background:
Infection, tissue damage and aging can cause inflammation with high levels of inflammatory
cytokines. Overproduction of inflammatory cytokines often leads to systemic inflammatory response
syndrome (SIRS), severe sepsis, and septic shock. However, prominent therapeutic targets have not been found,
although the incidence of sepsis is likely to increase annually. Our recent studies indicate that some RNA-binding
proteins, which control gene expression of inflammatory cytokines at the post-transcriptional level, may play a
critical role in inflammatory diseases such as sepsis.

Results:
1) One of the RNA-binding proteins, AT-rich interactive domain-containing 5a (Arid5a) promotes cytokine
production through control of mRNA half-lives of pro-inflammatory molecules such as IL-6, STAT3, T-bet,
and OX40 in activated macrophages and T cells. Arid5a KO mice are refractory to endotoxin shock, bleomycininduced
lung injury, and inflammatory autoimmune disease. 2) Chlorpromazine (CPZ), which is recognized as a
psychotic drug, impairs post-transcriptional gene expression of Il6 in LPS-stimulated macrophages: CPZ inhibits
the binding activity of Arid5a to the 3’UTR of Il6 mRNA, thereby destabilizing Il6 mRNA possibly through
suppression of Arid5a expression. 3) CPZ has strong suppressive effects on cytokine production such as TNF-α in
vivo. Mice with treatment of CPZ are resistant to lipopolysaccharide (LPS)-induced shock.

Conclusion:
Thus, Arid5a contributes to the activation of macrophages and T cells through positive control of
mRNA half-lives of inflammatory cytokines and its related molecules, which might lead to cytokine storm. Interestingly,
Arid5a was identified from an inhibitory effect of CPZ on IL-6 production in macrophages activated by
LPS. Therefore, CPZ derivatives or Arid5a inhibitors may have a potential to suppress severe sepsis through
control of post-transcriptional gene expression.
Cardioprotective Activity of Agaricus bisporus Against Isoproterenol- Induced Myocardial Infarction in Laboratory Animals
Authors: Bhushan Apoorva , Kulshreshtha Mayank 
Published: April 2018

Background:
Agaricus bisporus (A. bisporus) is an edible basidiomycete mushroom native
to grasslands in Europe and North America. A. bisporus, commonly known as white button mushroom
(WBM), is widely cultivated in most countries, and it constitutes the bulk of all mushrooms consumed
in the United States and Australia. Traditionally this fungus has used in the treatment of heart diseases.
Also it has anti-ageing property.Mushrooms have been found effective against cancer, cholesterol
reduction, stress, insomnia, asthma, allergies and diabetes.

Objective:
The present research was designed to appraise the cardioprotective activity of a hydroalcoholic
extract of Agaricus bisporus (EEAB) on Isoproterenol (ISO) induced myocardial infarction (MI)
in Albino Wistar rat. Traditionally, Agaricus bisporus is reported in the treatment of heart diseases,
cancer, cerebral stroke and anti-ageing property.

Materials and Methods:
Wistar rats of different sex were randomly split into five groups namely positive
control, negative control, standard, test-1 and test-2 and received distilled water, ISO (85 mg/kg),
Simvastatin (10 mg/kg/day, oral) and EEAB (200 and 400 mg/kg/day, p.o.) for 30 days, respectively.
MI was induced in rats by ISO at an interval of 24 hrs on 31 and 32 day and on the next day, blood
was amassed through retro-orbital plexus for the assessment of biochemical markers (cholesterol, lowdensity
lipoprotein, high-density lipoprotein, very low-density lipoprotein, triglycerides, alanine aminotransferase
and total protein) and finally, the rats were immolated by cervical dislocation. The heart
tissue was reaped instantly, cleaned with chilled isotonic saline and clasped in 10% buffered formalin
and used for the histopathological analysis.

Results:
ISO p.o. administration significantly elevated the cholesterol, low density lipoprotein, very
low density lipoprotein, triglycerides, alanine aminotransferase and aspartate aminotransferase levels
while it decreases high-density lipoprotein and total protein in plasma and administration of EEAB
decreases the level of cholesterol, low-density lipoprotein, very low-density lipoprotein, triglycerides,
alanine aminotransferase and aspartate aminotransferase levels while it increases high-density lipoprotein
and total protein levels. Pretreatment with EEAB protected the cardiotoxicity induced by ISO.
The histopathological findings support the analysis of biochemical parameters, ISO-induced myocardium
showed infracted zone with edema, inflammatory cells, lipid droplets, myocardial necrosis and
vacuolization of myofibrils which were reduced.

Conclusion:
It can be an outcome that EEAB possessed cardioprotective activity against experimental
and clinical studies of ISO-induced myocardial infarction in rats.
Sialic Acids Content Analysis of the Innovator and Biosimilar Darbepoetin Alfa by Fluorometric HPLC Assay
Authors: Huo Yanyan , He Jinjiao , Li Feng 
Published: April 2018

Background:Erythropoietin is a highly glycosylated protein hormone, used medically for the treatment of anemia associated with chronic renal disease. Due to patent expirations, we expect biosimilar erythropoietins to play an increasing role in healthcare in coming years. </P><P> Objective: Here, we have developed a chromatograpy method for determination of Neu5AC and Neu5Gc in darbepoetin alfa.Methods:Sialic acids (Sias) analysis provides the contents of the two most abundant sialic acids Neu5Ac and Neu5Gc. It has often been utilized for the evaluation of sialylated glycoprotein to ensure the biopharmtherapeutic safety and efficacy. In this work, the application of the DMB derivatization of Sias from darbepoetin alfa followed by the separation of the resulting adducts based on HPLC-FLD was presented.Results:Our work demonstrated that the method is characteristics of simple operation, and high reproducibility and sensitivity, and easy to set up for compliance analysis in a routine laboratory.Conclusion:By using a water:acetonitrile gradient, high resolution of Sias was obtained within a 1 min analysis time. The detection limits of NeuAc and NeuGc were 2.9 µg/L and 1.5 µg/L, respectively. The RSDs of the intraday and interday precisions in terms of retention time and peak areas of the analytes are below 1%, and from 3.8% to 4.2% respectively. Therefore, this developed method can be widely applied for simple determination of Neu5Ac, Neu5Gc, and O-acetylated Sias in the derivatized samples. Especially, high levels of O-acetylation were detected on darbepoetin alfa N-glycans, which are critical to establishing the bioequivalence of darbepoetin alfa biosimilars.
ATIVIDADE LABORAL EM DISCURSO: TENSÕES E GESTÃO DOS USOS DE SI EM JORNAIS DA EMPRESA HERA LABOR ACTIVITY IN SPEECH: TENSIONS AND USES OF ONESELF AT THE COMPANY HERA’S MAGAZINE
Authors: Haubrich Gislene Feiten , FREITAS Hernani César de 
Published: April 2018

Resumo: O estudo visa compreender como as tensões da gestão dos usos de si, na atividade laboral, são evidenciadas no ato de linguagem da empresa Hera. Trata-se de um estudo de caso, com abordagem qualitativa ancorada na análise teórico-ergo-discursiva. O corpus é composto por editoriais do jornal da empresa, publicados no período de janeiro/2012 a junho/2014. A análise é sustentada pela proposta semiolinguística de Charaudeau (2010) e o marco teórico decorre das noções de atividade laboral (SCHWARTZ; DURRIVE, 2007) e relações de poder (FOUCAULT, 2007; GALBRAITH, 1989). Como resultado principal pode-se apontar que o discurso da Hera seja normalizador, na intenção de restringir espaços do dizer e produzir efeitos de “verdade”, além de outorgar aos trabalhadores a vigilância uns dos outros, aspectos que tendem a estimular a competitividade.Palavras-chave: Trabalho. Discursos. Poder. Jornal de empresa. Abstract: The study aims to understand how the tensions of management of the uses of oneself, in labor activity, are highlighted in the discourse of Hera’s company. This is a case study with a qualitative approach and is anchored at theoretical-ergo-discursive analysis. The corpus consists of editorials of the company's magazine, published between January/2012 to June/2014. The analysis is supported by semiolinguistics proposed by Charaudeau (2010) and the theoretical framework stems from the work activity notions (SCHWARTZ; DURRIVE, 2007) and power relationships (FOUCAULT, 2007; GALBRAITH, 1989). The main result points out that the speech of Hera is normalizing, with the intention of restrict conversation spaces and wants produce effects of "truth", beyond to grant for workers mutual surveillance, aspects that tend to encourage competitiveness.Keywords: Work. Discourses. Power. Enterprise’s magazine.
NOTAS DE (IN)COMPATIBILIDADE ENTRE SEMIÓTICA E FENOMENOLOGIA NOTES DE (IN)COMPATIBILITÉ ENTRE SÉMIOTIQUE E PHÉNOMÉNOLOGIE
Authors: QUEIROZ Lucas Porto de , CAMPOS Norma Discini de 
Published: April 2018

RESUMO: Nosso objetivo neste artigo será cotejar e nos posicionar diante de uma questão tão delicada quanto cara a qualquer pesquisador, seja de filiação filosófica ou linguística, que se interesse pela significação humana. Interessa-nos investigar que pontos aproximam e distanciam semiótica e fenomenologia, fazendo ao mesmo tempo uma retomada de por que, em dado momento, a primeira se abeirou da segunda, naquilo que se convencionou chamar tournant phénoménologique da semiótica.Palavras-chave: Semiótica; Fenomenologia; Significação.RESUMÉ: Notre but dans ce article sera confronter et nous placer devant une question délicate e chère à tout les rechercheurs, aussi de filiation philosophique ou linguistique qui s'intéresse par la signification humaine. Interesse-nous rechercher quels points approchent et éloignent sémiotique et phénoménologie, et au même temps reprendre le motif qui a fait, à certain moment, la prémière s'approcher de la deuxième, dans le nommé tournant phénoménologique de la sémiotique. Mots-clés: Sémiotique; Phénoménologie; Signification.
The Effect of External Auditors on Managerial Slack
Authors: Fang Junxiong , He Lerong , Shaw Tara Shankar 
Published: April 2018

SYNOPSIS
We investigate the role of external auditors in constraining managerial slack. Using panel data on Chinese public firms, we find that firms hiring Big 8 auditors are associated with reduced managerial slack after controlling for the endogenous auditor choice. We also document that Big 8 auditors are more effective in mitigating slack in privately controlled firms and firms located in more developed regions. Moreover, we show that international Big 4 auditors are more effective than the domestic Big 4, and the Big 8 effect is more salient in more competitive and less regulated industries, and in industries with higher litigation risks. Finally, we document a positive relationship between managerial slack and audit fees, particularly in the presence of Big 8 auditors. Overall, our results suggest that high-quality external auditors play an important corporate governance role by serving as both bonding and controlling mechanisms to mitigate managerial exploitation of firm resources.
Data Availability: Data are publicly available from sources identified in the article.
Outcomes at 18 Months From a Community Health Worker and Peer Leader Diabetes Self-Management Program for Latino Adults
Authors: Spencer Michael S. , Kieffer Edith C. , Sinco Brandy , Piatt Gretchen , Palmisano Gloria , Hawkins Jaclynn , Lebron Alana , Espitia Nicolaus , Tang Tricia , Funnell Martha , Heisler Michele 
Published: April 2018

OBJECTIVE
This study evaluated the effectiveness of a community health worker (CHW) diabetes self-management education (DSME) program, followed by two different approaches to maintain improvements in HbA1c and other clinical and patient-centered outcomes over 18 months.

RESEARCH DESIGN AND METHODS
The study randomized 222 Latino adults with type 2 diabetes and poor glycemic control from a federally qualified health center to 1) a CHW-led, 6-month DSME program or 2) enhanced usual care (EUC). After the 6-month program, participants randomized to the CHW-led DSME were further randomized to 1) 12 months of CHW-delivered monthly telephone outreach (CHW-only) or 2) 12 months of weekly group sessions delivered by peer leaders (PLs) with telephone outreach to those unable to attend (CHW+PL). The primary outcome was HbA1c. Secondary outcomes were blood pressure, lipid levels, diabetes distress, depressive symptoms, understanding of diabetes self-management, and diabetes social support. Assessments were conducted at baseline and at 6, 12, and 18 months.

RESULTS
Participants in the CHW intervention at the 6-month follow-up had greater decreases in HbA1c (−0.45% [95% CI −0.87, −0.03]; P &lt; 0.05) and in diabetes distress (−0.3 points [95% CI −0.6, −0.03]; P &lt; 0.05) compared with EUC. CHW+PL participants maintained HbA1c improvements at 12 and 18 months, and CHW-only participants maintained improvements in diabetes distress at 12 and 18 months. CHW+PL participants also had significantly fewer depressive symptoms at 18 months compared with EUC (−2.2 points [95% CI −4.1, −0.3]; P &lt; 0.05). Participants in CHW-led DSME had significant improvements in diabetes social support and in understanding of diabetes self-management at 6 months relative to EUC, but these intervention effects were not sustained at 18 months.

CONCLUSIONS
This study demonstrates the effectiveness of a 6-month CHW intervention on key diabetes outcomes and of a volunteer PL program in sustaining key achieved gains. These are scalable models for health care centers in low-resource settings for achieving and maintaining improvements in key diabetes outcomes.
STATUS SOSIAL EKONOMI PETERNAK KAMBING PERANAKAN ETAWA (PE) DI DESA SUNGAI LANGKA, KECAMATAN GEDONG TATAAN, KABUPATEN PESAWARAN PROVINSI LAMPUNG
Authors: Rumiyani Tri , Hamdani Muhammad Dima Iqbal 
Published: April 2018

The aim of this research was to know social economic status of farmer groups Ettawa crossbred goat during the production and cost value of the milk. The research was held on July – August 2016 in Ettawa farmer groups in Sungai Langka Village, Gedong Tataan District, Pesawaran Regency, Lampung Province. Material of this research were 40 samples from three farmer groups : Tunas Muda, Sehati jaya and Margarini 6. The method of this research was a survey with purposive random sampling. Data were analyzed by descriptive analysis. The result showed each farmer groups had different social economic status during production and cost value of the milk. Keywords : Ettawa Crossbred Goat , Social Economic Status, Sungai Langka Village.