bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANTIMICROBIAL RESISTANCE IN PATHOGENS CAUSING URINARY TRACT INFECTIONS
Authors: Bezruk V V. , Blinder О. V. , Bezruk T.O. , Deyneka S.E. 
Published: June 2018

В Украине отмечается увеличение количества пациентов с инфекцией мочевыводящей системы.
Цель. Установить спектр чувствительности к антибиотикам основных групп возбудителей инфекций мочевой системы у населения г. Черновцы и Черновицкой области.
Материалы и методы. На протяжении 2009 - 2013 годов проведено бактериологическое исследование 2828 образцов мочи пациентов лечебных учреждений г. Черновцы и Черновицкой области с целью верификации диагноза инфекция мочевой системы (ИМС).
Результаты и обсуждение. Всего выделено 801 штамм бактерий и грибов в этиологически значимых количествах. Изучена чувствительность выделенных штаммов к 24 антибиотикам. Установлена зависимость антибиотикорезистентности основной группы возбудителей ИМС — энтеробактерий (исключая протей) от возраста и пола пациентов. Штаммы бактерий, относящиеся к основным группам возбудителей ИМС (энтеробактерии, псевдомонады) высокочувствительны к карбапенемам и аминогликозидам. Сохраняется относительно высокая чувствительность к цефалоспоринам 3 - 4 поколений (в большей мере у штаммов, выделенных от пациентов женского пола), фторхинолонам.
Выводы. Применение пенициллинов, цефалоспоринов 1 - 2 поколений, тетрациклинов, а также канамицина и левомицетина без бактериологического анализа мочи и определения антибиотикочувствительности не целесообразно.
BIOCHEMICAL MARKERS OF RENAL DYSFUNCTIONS IN CRITICALLY ILL FULL - TERM NEWBORNS
Authors: Babintseva A. 
Published: June 2018

Introduction. Full - term newborns with clinical signs of severe perinatal pathology constitute a high risk group of the formation of urinary system functional disorders, the diagnostic of which in the early neonatal period is complicated.
Objective of the research was to study the condition of renal functions in critically ill full - term newborns during the first week of their life by means of detection of specific biomarkers level in the blood serum and urine.
Materials and methods. A comprehensive clinical - paraclinical examination of 36 critically ill newborns (the main group) and 37 conditionally healthy newborns (the control group) has been conducted. Laboratory methods ofexamination included detection of the levels of creatinine, urea, sodium and potassium ions in the blood and urine, as well as protein, albumin, immunoglobulin G, a - - microglobulinand $ - microglobulinin urine.
Results and discussion. The neonates of the main group as compared to the control one presented statistically significant higher levels of creatinine (р<0,01) and urea (р<0,001) in the blood serum against the ground of lower glomerular filtration rate (р<0,05) and the level ofpotassium ions (р<0,01); in the urine — statistically significant lower level of creatinine (р<0,01), higher levels of urea (р<0,001) and sodium ions (р<0,05). Evaluation of urineproteinogramin the main group of newborns as compared to the control group enabled to find statistically significant higher levels of protein (р<0,01), albumin (р<0,01), immunoglobulin G (р<0,05), a - - microglobulin (р<0,01), $ - - microglobulin (р<0,01).
Conclusions. Critically ill full - term newborns with perinatal pathology receiving treatment in the Intensive Care Unit are under conditions of a complex influence of potentially nephrotoxic factors (hypoxia, reoxygenation - reperfusion, infection, artificial lung ventilation, infusion, inotropic, transfusion and antibacterial therapy). Severity of general condition, morpho - functional immaturity of the organism, multiple organ failure due to underlying perinatal pathology “obscure” renal symptoms and complicate the diagnostics of renal function disorders. The biochemical changes found in critically ill newborns require timely diagnostics to correct therapeutic measures on the stage of intensive therapy with the aim to prevent the development of severe renal pathology and chronic renal failure in future.
RATING EVALUATION OFSPECIALIZED MEDICAL CARE BYTHEPATIENTSNEPHROLOGIC PROFILE OFTHE UKRAINEPROVINSE
Authors: Kolesnyk M. , Kozlyuk N. , Nikolaenko S. , Stepanova N. , Gonchar Y. 
Published: June 2018

The aim of the work was to conduct a comparative analysis of indicators of the performance of nephrological services in the regions of Ukraine by using the method of complex statistical coefficients.
Materials and methods. Evaluation of the performance of the system of provision of nephrological services in the regions of Ukraine was made by studying the indicators that characterize the structure, use of health care resources, quality and efficiency of its provision submitted to National Register ofpatients with chronic kidney disease and patients with acute kidney injury (2015).
Results. By using rating evaluation methodology, it was identified place of relevant region by each indicator, by each area and by all areas of provision of nephrological services in the region as a whole. Conclusions. As a result of a comprehensive study of the condition of the system of providing nephrological service in the regions, there were identified ranking places of the administrative territories.
CYTOKINE IMMUNITYINCKD PATIENTS TREATED WITH HD, HDF, PD
Authors: Dryanska V.E. , Dudar I.O. , Shifris I. , Gonchar Yu.I. , Loboda O.M. , Galsenluk F.Z. , Krot V.F. 
Published: June 2018

Introduction. Cytokines play the corresponding role in the inflammatory processes and the development of endothelial dysfunction and therefore take an important place in the problem of systemic chronic inflammation (SCI) in patients with chronic kidney disease (CKD), stage V, who are treated with methods of the renal replacement therapy (RRT).
Aim of the work was to determine the features ofpro- and anti-inflammatory cytokines, VEGF in patients with CKD stage V D, depending on the method of RRT (HD, HDF, PD).
Materials and methods. There were examined 56 patients with CKD, st. V treated with methods of RRT: gr.1 received hemodialysis (HD) (15 p), gr. 2 - hemodiafiltration (HDF) (28 p) and gr. 3 – peritoneal dialysis (PD) (13p). The cytokines levels (IL-6, -8, -10, -18, TNF-a, VEGF) were determined in blood serum by means of ELIZA.
Results. The CKD, st. V patients treated with RRT showed really increased levels of pro-inflammatory blood cytokines (TNF-a, IL-8, IL-18) (p < 0.001) and VEGF as important factor of endothelial dysfunction, in dependence on RRT the groups 1-3 did not differ (p > 0.05). In comparison with healthy donors, in patients of gr. 3 the level of antiinflammatory IL-10 was the highest (p < 0.001) in comparison with gr.1 (p = 0.080) andgr.2 (p = 0,043) (corresponding HD and HDF), and the ratio IL-18/IL-10 was really more low in comparison with both other groups (p = 0.035).
Conclusion. The high level of serum cytokines confirms the SCI availability in patients with CKD,st.V; the patients treated with PD showed the lower degree of inflammatory reactions by the data of balance between pro/anti-inflammatory immunity mediators.
Sistem Manajemen Inventori Komputer Menggunakan Near Field Communication Berbasis Android Studi Kasus di STIE Pelita Indonesia Pekanbaru
Authors: Hamzah Muhammad Luthfi , Purwati Astri Ayu 
Published: June 2018

Higher education is an institution that is heavily influenced by technological advances,especially in the field of computer technology. The purpose of this study is to create a computer inventory management system in higher education which is previously using manuals system become technology based system in order to work more effective and efficient. The research method used is design of inventory tracking system application using NFC android based. The results showed that by using Inventory Tracking Systems model is more effectiveand efficient to identify any inventory information in the computer lab STIE Pelita Indonesia
Keywords :Inventory Tracking, RFID, Near Field Communication, NFC
Pengaruh Deskripsi Pekerjaan terhadap Kinerja Pegawai Negeri Sipil pada Kantor Camat Tembilahan
Authors: Syelviani Meilisa 
Published: June 2018

Job description or work flows is an important thing that needed in every company or organization. The purpose of this study is to determine the effect of job description on civil servants performance in Tembilahan subdistrict office .Independent variable of this research is job description, and dependent variable is performance. Population of this research are 30 Civil Servants workers in Tembilahan subdistrict office.Sampling technique used is total sampling or census. Data analysis used is linear regression. Theresult showed that there is significance influence between job description against civil servants performance in Tembilahan Subdistrict office with the number of adjusted R square 72 percent, means the other 28 percent of employees performance influences by another factors.
Keywords: Job Descriptions, Performance
Faktor-Faktor yang Mempengaruhi Kualitas Hidup Pasien Chronic Kidney Disease yang Menjalani Hemodialisa di Ruang Hemodialisa
Authors: Rustandi Handi , Tranado Hengky , Pransasti Tinalia 
Published: June 2018

This study aimed to describe the factors that affect the quality of life of patients with CRF who undergo hemodialysis in dr. M. Yunushospital in Bengkulu 2016. The population of study is 205 people, the sampling technique used was an accidental sampling with a sample of 67 respondents.The results showed nearly all respondents aged smaller than 20 and greather than 35 years, more than the majority of respondents were female, more than the majority of respondents had pretty income or more, almost half of respondents had high levels of depression, more than the majority of respondents had either the family support, more than the majority of respondents had a high quality of life, there was a correlation between age, gender, producer, depression, and family support with quality of life, there was a relationship between sex with the quality of life for CRF patients undergoing hemodialysis in dr. M. Yunus Hospital in Bengkulu 2016.It is advisable for the public to provide health education for families of patients with CRF who undergo hemodialysis therapy on the importance of family support in improving the quality of life of family members.
Keywords: Accidental Sampling, Chronic Kidney Disease, Hemodialysis, Quality of Life.
Stimulasi Permainan Puzzle Berpengaruh terhadap Perkembangan Sosial dan Kemandirian Anak Usia Prasekolah
Authors: Setyaningsih Tunggul Sri Agus , Wahyuni Hesti 
Published: June 2018

The aimed of study to analyze theinfluenced of puzzle game stimulation on socialization and independence development in preschoolers.This research was a quantitative research with Quasi experimental one group pre test post test design. The samples were 5 years old 60 months children with development in doubt on socialization and independence aspects which amounted to 17 people by purposive sampling technique. The instrument of this research was using a puzzle and Pre-screening Children Development Questioner. The statistical test used wilcoxon test for the children development status before and after the intervention showed a significant value 0,000 pvalue smaller than 0,05 so it can be concluded that there is a significant effect between puzzle stimulation to socialization and independence development.
Keywords: Development Area, Puzzle, Quasi eksperimental
Encephaloduroarteriosynangiosis for hemorrhagic moyamoya disease: long-term outcome of a consecutive series of 95 adult patients from a single center
Authors: Wang Qian-Nan , Bao Xiang-Yang , Zhang Yong , Zhang Qian , Li De-Sheng , Duan Lian 
Published: June 2018

OBJECTIVEThe objective of this study was to investigate long-term outcomes after encephaloduroarteriosynangiosis (EDAS) for the treatment of hemorrhagic moyamoya disease (MMD) and identify the risk factors for recurrent hemorrhages.METHODSThe authors retrospectively reviewed 95 patients with hemorrhagic MMD who were treated with EDAS at 307th Hospital PLA. Clinical features, angiographic findings, and clinical outcomes were investigated. Rebleeding incidences were compared between anterior or posterior hemorrhagic sites. Kaplan-Meier survival analysis and Cox proportional hazards regression models were used to estimate rebleeding risks after EDAS.RESULTSThe average age at symptom onset was 37.1 years (range 20–54 years) for adult patients. The ratio of female to male patients was 1.16:1. In 61 of 95 hemorrhagic hemispheres (64.2%), the anterior choroidal artery (AChA) or posterior communicating artery (PCoA) was extremely dilated, with extensive branches beyond the choroidal fissure, which only occurred in 28 of 86 nonhemorrhagic hemispheres (32.6%). Fifty-seven incidences were classified as anterior hemorrhages and 38 as posterior. Sixteen of 95 patients (16.8%) suffered cerebral rebleeding after a median follow-up duration of 8.5 years. The annual rebleeding rate was 2.2% per person per year. The incidence rate was higher for the posterior group than for the anterior group, but this difference was not statistically significant (p > 0.05). Cox regression analysis revealed that the age of symptom onset (OR 1.075, 95% CI 1.008–1.147, p = 0.028) was a predictor of rebleeding strokes.CONCLUSIONSThrough long-term follow up, EDAS proved beneficial for patients with hemorrhagic MMD. Dilation of the AChA-PCoA is associated with the initial hemorrhage of MMD, and rebleeding is age-related. Patients with hemorrhagic MMD should undergo follow-up over the course of their lives, even when neurological status is excellent.
Rates and predictors of seizure outcome after corpus callosotomy for drug-resistant epilepsy: a meta-analysis
Authors: Chan Alvin Y. , Rolston John D. , Lee Brian , Vadera Sumeet , Englot Dario J. 
Published: June 2018

OBJECTIVECorpus callosotomy is a palliative surgery for drug-resistant epilepsy that reduces the severity and frequency of generalized seizures by disconnecting the two cerebral hemispheres. Unlike with resection, seizure outcomes remain poorly understood. The authors systematically reviewed the literature and performed a meta-analysis to investigate rates and predictors of complete seizure freedom and freedom from drop attacks after corpus callosotomy.METHODSPubMed, Web of Science, and Scopus were queried for primary studies examining seizure outcomes after corpus callosotomy published over 30 years. Rates of complete seizure freedom or drop attack freedom were recorded. Variables showing a potential relationship to seizure outcome on preliminary analysis were subjected to formal meta-analysis.RESULTSThe authors identified 1742 eligible patients from 58 included studies. Overall, the rates of complete seizure freedom and drop attack freedom after corpus callosotomy were 18.8% and 55.3%, respectively. Complete seizure freedom was significantly predicted by the presence of infantile spasms (OR 3.86, 95% CI 1.13–13.23), normal MRI findings (OR 4.63, 95% CI 1.75–12.25), and shorter epilepsy duration (OR 2.57, 95% CI 1.23–5.38). Freedom from drop attacks was predicted by complete over partial callosotomy (OR 2.90, 95% CI 1.07–7.83) and idiopathic over known epilepsy etiology (OR 2.84, 95% CI 1.35–5.99).CONCLUSIONSThe authors report the first systematic review and meta-analysis of seizure outcomes in both adults and children after corpus callosotomy for epilepsy. Approximately one-half of patients become free from drop attacks, and one-fifth achieve complete seizure freedom after surgery. Some predictors of favorable outcome differ from those in resective epilepsy surgery.
Microhemorrhagic transformation of ischemic lesions on T2*-weighted magnetic resonance imaging after Pipeline embolization device treatment
Authors: Nakae Ryuta , Nagaishi Masaya , Kawamura Yosuke , Tanaka Yoshihiro , Hyodo Akio , Suzuki Kensuke 
Published: June 2018

OBJECTIVEThe authors sought to demonstrate that hemorrhagic transformation of ischemic lesions is the main cause of delayed intracerebral hemorrhage (ICH) after Pipeline embolization device (PED) treatment and to estimate the rate of hemorrhagic transformation of new postprocedure ischemic lesions.METHODSPatients who underwent PED placement (PED group) from November 2015 to March 2017 or stent-mediated embolization (EN group) from December 2010 to October 2015 were retrospectively analyzed. Pre- and postprocedural MR images and 6-month follow-up MR images for each patient were scored for the presence of postprocedural bland ischemic and hemorrhagic lesions using diffusion-weighted MRI (DWI) and T2*-weighted MRI (T2*WI), respectively.RESULTSThe PED group comprised 28 patients with 30 intracranial aneurysms, and the EN group comprised 24 patients with 27 intracranial aneurysms. The mean number of ischemic lesions on DWI 1 day postprocedure was higher in the PED group than in the EN group (5.2 vs 2.7, p = 0.0010). The mean number of microbleeds detected on T2*WI 6 months postprocedure was higher in the PED group than in the EN group (0.6 vs 0.15, p = 0.028). A total of 36.7% of PED-treated patients exhibited new microbleeds on T2*WI at 6 months postprocedure, with at least 77.8% of these lesions representing hemorrhagic transformations of the new ischemic lesions observed on day 1 postprocedure. The rate of adjunctive coil embolization (27.3% vs 0.0%, p = 0.016) and the mean number of ischemic lesions observed 1 day postprocedure (6.6 vs 4.3, p = 0.020) were predictors of subsequent microbleeds in the PED group.CONCLUSIONSNew microbleeds detected using T2*WI at 6 months postprocedure were more common after PED treatment than after stent-mediated embolization. Approximately three-quarters of these lesions were hemorrhagic transformations of new ischemic lesions observed on day 1 postprocedure. Prevention of intraprocedural or postprocedural infarcts is necessary to reduce the risk of hemorrhagic complications following PED placement.
The surgical outcome of decompression alone versus decompression with limited fusion for degenerative lumbar scoliosis
Authors: Masuda Kenji , Higashi Takayuki , Yamada Katsutaka , Sekiya Tatsuhiro , Saito Tomoyuki 
Published: June 2018

OBJECTIVEThe aim of this study was to assess the usefulness of radiological parameters for surgical decision-making in patients with degenerative lumbar scoliosis (DLS) by comparing the clinical and radiological results after decompression or decompression and fusion surgery.METHODSThe authors prospectively planned surgical treatment for 298 patients with degenerative lumbar disease between September 2005 and March 2013. The surgical method used at their institution to address intervertebral instability is precisely defined based on radiological parameters. Among 64 patients with a Cobb angle ranging from 10° to 25°, 57 patients who underwent follow-up for more than 2 years postoperatively were evaluated. These patients were divided into 2 groups: those in the decompression group underwent decompression alone (n = 25), and those in the fusion group underwent decompression and short segmental fusion (n = 32). Surgical outcomes were reviewed, including preoperative and postoperative Cobb angles, lumbar lordosis based on radiological parameters, and Japanese Orthopaedic Association (JOA) scores.RESULTSThe JOA scores of the decompression group and fusion group improved from 5.9 ± 1.6 to 10.0 ± 2.8 and from 7.2 ± 2.0 to 11.3 ± 2.8, respectively, which was not significantly different between the groups. At the final follow-up, the postoperative Cobb angle in the decompression group changed from 14° ± 2.9° to 14.3° ± 6.4° and remained stable, while the Cobb angle in the fusion group decreased from 14.8° ± 4.0° to 10.0° ± 8.5° after surgery.CONCLUSIONSThe patients in both groups demonstrated improved JOA scores and preserved Cobb angles after surgery. The improvement in JOA scores and preservation of Cobb angles in both groups show that the evaluation of spinal instability using radiological parameters is appropriate for surgical decision-making.
Encephaloduroarteriosynangiosis for pediatric moyamoya disease: long-term follow-up of 100 cases at a single center
Authors: Zhang Yong , Bao Xiang-Yang , Duan Lian , Yang Wei-Zhong , Li De-Sheng , Zhang Zheng-Shan , Han Cong , Zhao Feng , Zhang Qian , Wang Qian-Nan 
Published: June 2018

OBJECTIVEThe object of this study was to summarize the long-term effect of encephaloduroarteriosynangiosis (EDAS) for the treatment of pediatric moyamoya disease (MMD) and to investigate factors influencing the clinical outcomes of EDAS.METHODSClinical features, angiographic findings, and clinical outcomes were analyzed among MMD patients younger than 18 years who had been treated with EDAS between 2002 and 2007 at the authors’ institution. The Kaplan-Meier method was used to estimate stroke risk after EDAS. Predictors of neurological outcome were assessed.RESULTSOne hundred fifteen patients were identified. The mean age at symptom onset was 7.3 ± 4.0 years. The incidence of familial MMD was 11.3%. The female/male ratio was 1:1.16. A total of 232 EDAS procedures were performed, and the incidence of postoperative complications was 3%. Postoperative digital subtraction angiography was performed in 54% of the patients, and about 80% of the hemispheres showed good or excellent results. Neovascularization showed significant correlations with delay time (from symptom onset to first operation), Suzuki stage, and preoperative stroke (all p < 0.05). Clinical follow-up was available in 100 patients with a mean follow-up of 124.4 ± 10.5 months. Ten-year cumulative survival was 96.5% after surgery, and the risk of stroke was 0.33%/person-year. An independent life with no significant disability was reported by 92% of the patients. A good outcome correlated with a low Suzuki stage (p = 0.001). Older children and those without preoperative stroke had better clinical outcomes (p < 0.05).CONCLUSIONSOn the basis of long-term follow-up data, the authors concluded that EDAS is a safe and effective treatment for pediatric MMD, can reduce the risk of subsequent neurological events, and can improve quality of life. The risk of ischemia-related complications was higher in younger patients, and older children showed better outcomes. Compensation was greater with more prominent cerebral ischemia. The long-term clinical outcome largely depended on the presence and extent of preoperative stroke.