bluuebunny/crossref_metadata_2025_split huggingface dataset:
Das Rezept für die Langlebigkeit von Unternehmen – aus Sicht des “Innovationsmanagements”
Authors: Griesar Klaus , Bessant John , Bernschneider‐Reif Sabine 
Published: March 2018

AbstractEin Wort der Warnung gleich zu Beginn: Dieses Abstract stellt keine Zusammenfassung bahnbrechender Erkenntnisse oder Schlussfolgerungen dar. Ganz im Gegenteil. Es möchte lediglich die Neugier dafür wecken, was unternehmerisches Überleben eigentlich bedeutet. Gibt es ein Geheimrezept, das Unternehmen befolgen könnten, um zu überleben? Die Antworten kommen weder aus den bescheidenen und traditionellen Studierstuben von Philosophen noch aus der Durchsicht moderner, faktenbasierter Studien aus den Büroräumen (und den hochbezahlten Meinungen) von Unternehmensberatern. Den archimedischen Punkt, von dem aus wir objektiv der Frage nach dem unternehmerischen Überleben nachgehen könnten, gibt es schlichtweg nicht. Aber wir können 7 Analogien (oder Metaphern) als intellektuelle Sprungbretter bemühen, welche Raum für neue Sichtweisen schaffen könnten. Innovation spielt für das unternehmerische Überleben ganz offensichtlich eine wichtige Rolle; dennoch ist diese naturgemäß eine recht chaotische Angelegenheit. Um dem Chaos Form zu verleihen, stellen wir in diesem Abstract einige Schlüsselbegriffe in alphabetischer Reihenfolge vor. Wir beginnen mit A, das für Ambidextrie, Architektur und Ameisenkolonien steht. Dann folgt B für Begriffe wie (mentale) Boxen und Biodiversität. Natürlich spielt auch C eine große Rolle – wir haben bereits verraten, dass Neugier (Curiosity) Teil der Antwort ist. Weiter geht es mit D (Darwin, DNS und Diskontinuität) und E (Erdbeben und Evolution). Eine weitere Warnung zum Abschluss: Dieser Beitrag hat nicht die Absicht, die reichhaltige und komplexe Geschichte des Unternehmens Merck KGaA, Darmstadt, Germany, zu beschreiben. Zum Abschluss dieses Essays folgt lediglich – in Würdigung dieser Geschichte – ein Epilog, in dem einer der Protagonisten der 350 Jahre währenden Reise des Unternehmens – Emanuel Merck – auf die Bühne treten und “die Geschichte für sich selbst sprechen lassen soll.” Immer noch neugierig?
Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions
Authors: Denis Mathieu , Pancholi Jessica , Jobe Kajally , Watkinson Michael , Goldup Stephen M. 
Published: March 2018

AbstractAlthough metal‐ion‐binding interlocked molecules have been under intense investigation for over three decades, their application as scaffolds for the development of sensors for metal ions remains underexplored. In this work, we demonstrate the potential of simple rotaxanes as metal‐ion‐responsive ligand scaffolds through the development of a proof‐of‐concept selective sensor for Zn2+.
Temperature‐Dependent Atomic Models of Detergent Micelles Refined against Small‐Angle X‐Ray Scattering Data
Authors: Ivanović Miloš T. , Bruetzel Linda K. , Lipfert Jan , Hub Jochen S. 
Published: March 2018

AbstractSurfactants have found a wide range of industrial and scientific applications. In particular, detergent micelles are used as lipid membrane mimics to solubilize membrane proteins for functional and structural characterization. However, an atomic‐level understanding of surfactants remains limited because many experiments provide only low‐resolution structural information on surfactant aggregates. In this work, small‐angle X‐ray scattering is combined with molecular dynamics simulations to derive fully atomic models of two maltoside micelles at temperatures between 10 °C and 70 °C. The micelles take the shape of general tri‐axial ellipsoids and decrease in size and aggregation number with increasing temperature. Density profiles of hydrophobic groups and water along the three principal axes reveal that the minor micelle axis closely mimics lipid membranes. The results suggest that coupling atomic simulations with low‐resolution data allows the structural characterization of surfactant aggregates.
Transient and Persistent Room‐Temperature Mechanoluminescence from a White‐Light‐Emitting AIEgen with Tricolor Emission Switching Triggered by Light
Authors: Li Jian‐An , Zhou Jinghong , Mao Zhu , Xie Zongliang , Yang Zhan , Xu Bingjia , Liu Cong , Chen Xin , Ren Dingyang , Pan Hui , Shi Guang , Zhang Yi , Chi Zhenguo 
Published: March 2018

AbstractPersistent luminescence from purely organic materials is basically triggered by light and electricity, which largely confines its practical applications. A purely organic AIEgen exhibits not only persistent photoluminescence, but also transient and persistent room‐temperature mechanoluminescence. By simply turning on and off a UV lamp, tricolor emission switching between blue, white, and yellow was achieved. The data from single‐crystal structure analysis and theoretical calculation suggest that mechanism of the observed persistent mechanoluminescence (pML) is correlated with the strong spin–orbit coupling of the bromine atom, as well as the formation of H‐aggregates and restriction of intramolecular motions in noncentrosymmetric crystal structure. These results outline a fundamental principle for the development of new pML materials, providing an important step forward in expanding the application scope of persistent luminescence.
A Cell‐Targeted Non‐Cytotoxic Fluorescent Nanogel Thermometer Created with an Imidazolium‐Containing Cationic Radical Initiator
Authors: Uchiyama Seiichi , Tsuji Toshikazu , Kawamoto Kyoko , Okano Kentaro , Fukatsu Eiko , Noro Takahiro , Ikado Kumiko , Yamada Sayuri , Shibata Yuka , Hayashi Teruyuki , Inada Noriko , Kato Masaru , Koizumi Hideki , Tokuyama Hidetoshi 
Published: March 2018

AbstractA cationic fluorescent nanogel thermometer based on thermo‐responsive N‐isopropylacrylamide and environment‐sensitive benzothiadiazole was developed with a new azo compound bearing imidazolium rings as the first cationic radical initiator. This cationic fluorescent nanogel thermometer showed an excellent ability to enter live mammalian cells in a short incubation period (10 min), a high sensitivity to temperature variations in live cells (temperature resolution of 0.02–0.84 °C in the range 20–40 °C), and remarkable non‐cytotoxicity, which permitted ordinary cell proliferation and even differentiation of primary cultured cells.
Dual Functionalization of α‐Monoboryl Carbanions through Deoxygenative Enolization with Carboxylic Acids
Authors: Sun Wei , Wang Lu , Xia Chungu , Liu Chao 
Published: March 2018

AbstractA dual functionalization of 1,1‐diborylalkanes through deoxygenative enolization with carboxylic acids was developed. 1,1‐Diborylalkanes were activated by MeLi to generate α‐monoboryl carbanions. In situ IR spectroscopy indicated an interaction between carboxylic acid and 1,1‐diborylalkane before addition of the activation reagent. Release of the active α‐monoboryl carbanion from the masked form was necessary for its reaction with carboxylate to afford enolate species. Electrophilic trapping of enolate species with various electrophiles achieved dual functionalization of 1,1‐diborylalkanes to afford a variety of α‐mono, di‐, and tri‐substituted ketones.
Vis/NIR‐ und Raman‐Untersuchung der Wechselwirkung von Gastmolekülen mit Co‐MOF‐74
Authors: Strauss Ina , Mundstock Alexander , Hinrichs Dominik , Himstedt Rasmus , Knebel Alexander , Reinhardt Carsten , Dorfs Dirk , Caro Jürgen 
Published: March 2018

AbstractStäbchenförmige Co‐MOF‐74‐Kristalle wurden über ein Solvothermalverfahren synthetisiert, um die Wechselwirkungen mit Gasen zu untersuchen. Bei der Bestrahlung von Co‐MOF‐74 mit polarisiertem Licht weisen die Kristalle ein stark anisotropes Absorptionsverhalten auf. Des Weiteren wurden die Wechselwirkungen von Co‐MOF‐74 mit den Gastmolekülen CO2, Propan, Propen, Ar, MeOH und H2O mithilfe verschiedener spektroskopischer Methoden untersucht. Wechselwirkungs‐abhängige Peak‐Verschiebungen der Co‐MOF‐74‐Banden im Vis/NIR‐Bereich wurden beobachtet. Sowohl im sichtbaren als auch im Nah‐IR‐Bereich wird die maximale Absorption selektiv, entsprechend der Intensität der CoII‐Gastmolekül‐Wechselwirkung, verschoben. Aufgrund ihrer unterschiedlichen Wechselwirkungen mit Co‐MOF‐74 war es möglich, Propan und Propen bei Raumtemperatur zu unterscheiden. Raman‐Spektroskopisch konnte eine Änderung des Schwingungsverhaltens von Co‐MOF‐74 bei Gasadsorption nachgewiesen werden. Außerdem wurde eine charakteristische Verschiebung der Peak‐Maxima durch die Adsorption von H2O gezeigt.
Synthesis of (bis)Silicon Complexes of [38], [37], and [36]Octaphyrins: Aromaticity Switch and Stable Radical Cation
Authors: Ishida Shin‐ichiro , Kim Jinseok , Shimizu Daiki , Kim Dongho , Osuka Atsuhiro 
Published: March 2018

AbstractSilicon complexation of a [38]octaphyrin (1) was accomplished by reaction with an excess amount of MeSiCl3 in the presence of N,N‐diisopropylethylamine, thus giving an aromatic [38]octaphyrin bis(silicon) complex 2. This complex was interconvertible with an antiaromatic [36]octaphyrin congener (3) by oxidation with MnO2 and reduction with NaBH4. Curiously, mild oxidation of 2 with ferrocenium hexafluorophosphate afforded a [37]octaphyrin bis(silicon) complex 4 as an stable radical cation that can be stored under ambient conditions in the solid state. Owing to the two NNNCC‐five‐coordinated Si atoms bearing trigonal bipyramidal geometry, these octaphyrin bis(silicon) complexes take on similar and rigid figure‐of‐eight structures with different consecutive numbers of conjugated π‐electrons (38, 37, and 36), and are all stable.
Asymmetric [3+2] Photocycloadditions of Cyclopropanes with Alkenes or Alkynes through Visible‐Light Excitation of Catalyst‐Bound Substrates
Authors: Huang Xiaoqiang , Lin Jiahui , Shen Tianqi , Harms Klaus , Marchini Marianna , Ceroni Paola , Meggers Eric 
Published: March 2018

AbstractThe herein reported visible‐light‐activated catalytic asymmetric [3+2] photocycloadditions between cyclopropanes and alkenes or alkynes provide access to chiral cyclopentanes and cyclopentenes, respectively, in 63–99 % yields and with excellent enantioselectivities of up to >99 % ee. The reactions are catalyzed by a single bis‐cyclometalated chiral‐at‐metal rhodium complex (2–8 mol %) which after coordination to the cyclopropane generates the visible‐light‐absorbing complex, lowers the reduction potential of the cyclopropane, and provides the asymmetric induction and overall stereocontrol. Enabled by a mild single‐electron‐transfer reduction of directly photoexcited catalyst/substrate complexes, the presented transformations expand the scope of catalytic asymmetric photocycloadditions to simple mono‐acceptor‐substituted cyclopropanes affording previously inaccessible chiral cyclopentane and cyclopentene derivatives.
Metal–Organic Framework (MOF) Nanorods, Nanotubes, and Nanowires
Authors: Arbulu Roberto C. , Jiang Ying‐Bing , Peterson Eric J. , Qin Yang 
Published: March 2018

AbstractNew mechanisms for the controlled growth of one‐dimensional (1D) metal–organic framework (MOF) nano‐ and superstructures under size‐confinement and surface‐directing effects have been discovered. Through applying interfacial synthesis templated by track‐etched polycarbonate (PCTE) membranes, congruent polycrystalline zeolitic imidazolate framework‐8 (ZIF‐8) solid nanorods and hollow nanotubes were found to form within 100 nm membrane pores, while single crystalline ZIF‐8 nanowires grew inside 30 nm pores, all of which possess large aspect ratios up to 60 and show preferential crystal orientation with the {100} planes aligned parallel to the long axis of the pore. Our findings provide a generalizable method for controlling size, morphology, and lattice orientation of MOF nanomaterials.
The Recipe for Corporate Longevity: From the Perspective of “Managing Innovation”
Authors: Griesar Klaus , Bessant John , Bernschneider‐Reif Sabine 
Published: March 2018

AbstractThe elephant is in the room—a metaphorical idiom for an obvious problem or risk that nobody wants to discuss. This abstract is not intended to be a summary, to reveal major findings, or unveil conclusions. On the contrary, it is aimed to provoke curiosity as to the question of corporate survival. Is there any recipe to be followed for companies to achieve this? The answer comes neither from the modest and traditional study rooms of philosophers nor the recent fact‐based studies from the offices (and well‐paid opinions) of business consultants. The Archimedean point from which we can objectively explore the subject of corporate survival does not exist. Instead we offer seven analogies (or metaphors) as intellectual platforms where new perspectives can be considered. Innovation obviously plays a major role in corporate survival—yet, by its nature all innovation is messy. In order to reduce entropy, this abstract reveals some keywords in alphabetical order starting from A, such as ambidexterity, architecture, and ant colonies, moving on to B, such as, (mental) boxes and biodiversity. For obvious reasons, C plays a major role—sufficiently that we have already revealed curiosity as one part of the answer—treading over to D (Darwin, DNA, and discontinuity), followed by E (earthquakes and evolution). As a final warning signal in order to manage the expectation: It is not the intention of this article to give a comprehensive overview about the rich and complex history of Merck KGaA, Darmstadt, Germany. Indeed, only the final chapter will provide reference to this company: Before the curtains will finally close, an epilogue will start in which one of the protagonists of the 350‐year journey of the company—Emanuel Merck—will appear on the stage and “let history speak for itself”. Still curious?
Catalytic C−H Trifluoromethoxylation of Arenes and Heteroarenes
Authors: Zheng Weijia , Morales‐Rivera Cristian A. , Lee Johnny W. , Liu Peng , Ngai Ming‐Yu 
Published: March 2018

AbstractThe intermolecular C−H trifluoromethoxylation of arenes remains a long‐standing and unsolved problem in organic synthesis. Herein, we report the first catalytic protocol employing a novel trifluoromethoxylating reagent and redox‐active catalysts for the direct (hetero)aryl C−H trifluoromethoxylation. Our approach is operationally simple, proceeds at room temperature, uses easy‐to‐handle reagents, requires only 0.03 mol % of redox‐active catalysts, does not need specialized reaction apparatus, and tolerates a wide variety of functional groups and complex structures such as sugars and natural product derivatives. Importantly, both ground‐state and photoexcited redox‐active catalysts are effective. Detailed computational and experimental studies suggest a unique reaction pathway where photoexcitation of the trifluoromethoxylating reagent releases the OCF3 radical that is trapped by (hetero)arenes. The resulting cyclohexadienyl radicals are oxidized by redox‐active catalysts and deprotonated to form the desired products of trifluoromethoxylation.
Enzyme‐MOF Nanoreactor Activates Nontoxic Paracetamol for Cancer Therapy
Authors: Lian Xizhen , Huang Yanyan , Zhu Yuanyuan , Fang Yu , Zhao Rui , Joseph Elizabeth , Li Jialuo , Pellois Jean‐Philippe , Zhou Hong‐Cai 
Published: March 2018

AbstractProdrug activation, by exogenously administered enzymes, for cancer therapy is an approach to achieve better selectivity and less systemic toxicity than conventional chemotherapy. However, the short half‐lives of the activating enzymes in the bloodstream has limited its success. Demonstrated here is that a tyrosinase‐MOF nanoreactor activates the prodrug paracetamol in cancer cells in a long‐lasting manner. By generating reactive oxygen species (ROS) and depleting glutathione (GSH), the product of the enzymatic conversion of paracetamol is toxic to drug‐resistant cancer cells. Tyrosinase‐MOF nanoreactors cause significant cell death in the presence of paracetamol for up to three days after being internalized by cells, while free enzymes totally lose activity in a few hours. Thus, enzyme‐MOF nanocomposites are envisioned to be novel persistent platforms for various biomedical applications.
An Extra‐Large‐Pore Zeolite with 24×8×8‐Ring Channels Using a Structure‐Directing Agent Derived from Traditional Chinese Medicine
Authors: Zhang Chuanqi , Kapaca Elina , Li Jiyang , Liu Yunling , Yi Xianfeng , Zheng Anmin , Zou Xiaodong , Jiang Jiuxing , Yu Jihong 
Published: March 2018

AbstractExtra‐large‐pore zeolites have attracted much interest because of their important applications for processing larger molecules. Although great progress has been made in academic science and industry, it is challenging to synthesize these materials. A new extra‐large‐pore zeolite SYSU‐3 (Sun Yat‐sen University no. 3) has been synthesized by using a novel sophoridine derivative as an organic structure‐directing agent (OSDA). The framework structure was solved and refined using continuous rotation electron diffraction (cRED) data from nanosized crystals. SYSU‐3 exhibits a new zeolite framework topology, which has the first 24×8×8‐ring extra‐large‐pore system and a framework density (FD) as low as 11.4 T/1000 Å3. The unique skeleton of the OSDA plays an essential role in the formation of the distinctive zeolite structure. This work provides a new perspective for developing new zeolitic materials by using alkaloids as cost‐effective OSDAs.
A High‐Energy‐Density Potassium Battery with a Polymer‐Gel Electrolyte and a Polyaniline Cathode
Authors: Gao Hongcai , Xue Leigang , Xin Sen , Goodenough John B. 
Published: March 2018

AbstractA safe, rechargeable potassium battery of high energy density and excellent cycling stability has been developed. The anion component of the electrolyte salt is inserted into a polyaniline cathode upon charging and extracted from it during discharging while the K+ ion of the KPF6 salt is plated/stripped on the potassium‐metal anode. The use of a p‐type polymer cathode increases the cell voltage. By replacing the organic‐liquid electrolyte in a glass‐fiber separator with a polymer‐gel electrolyte of cross‐linked poly(methyl methacrylate), a dendrite‐free potassium anode can be plated/stripped, and the electrode/electrolyte interface is stabilized. The potassium anode wets the polymer, and the cross‐linked architecture provides small pores of adjustable sizes to stabilize a solid‐electrolyte interphase formed at the anode/electrolyte interface. This alternative electrolyte/cathode strategy offers a promising new approach to low‐cost potassium batteries for the stationary storage of electric power.
Synthesis of CuS nanoparticles loaded on activated carbon composite for ultrasound‐assisted adsorption removal of dye pollutants: Process optimization using CCD‐RSM, equilibrium and kinetic studies
Authors: Dastkhoon Mehdi , Ghaedi Mehrorang , Asfaram Arash , Javadian Hamedreza 
Published: March 2018

In this study, the CuS nanoparticles loaded on activated carbon (CuS‐NPs‐AC) composite was synthesized and then, characterized by XRD and FE‐SEM analyses. The prepared composite was used as a potential adsorbent for the simultaneous ultrasound‐assisted removal of Indigo Carmine (IC) and Safranin‐O (SO). The CuS‐NPs‐AC dose (0.01‐0.03 g), sonication time (1‐5 min), initial SO concentration (5‐15 mg L‐1) and initial IC concentration (5‐15 mg L‐1) as expectable effective parameters were studied by central composite design (CCD) under response surface methodology (RSM) to obtain an useful knowledge about the effect of simultaneous interaction between IC and SO on their removal percentage. The optimum SO and IC removal percentages were determined to be 98.24 and 97.15% at pH = 6, 0.03 g of the CuS‐NPs‐AC, 3 min sonication time, 12 and 10 mg L‐1 of IC and SO. The values of coefficient of determination (R2) for SO and IC were 0.9608 and 0.9796, respectively, indicating the favorable fitness of the experimental data to the second order polynomial regression model. The isotherm data were well correlated with Freundlich model. The maximum monolayer adsorption capacities of 87.5 and 69.90 mg g‐1 at room temperature for IC and SO in the investigated binary system expressed the high efficiency of the novel adsorbent for water cleanup within a short time. The investigation of correlation between time and rate of adsorption revealed that IC and SO adsorption onto the CuS‐NPs‐AC followed pseudo‐second‐order and intra‐particle diffusion simultaneously.
Investigation of Lipid Oxidation in the Raw Materials of a Topical Skin Formulation: A Topical Skin Formulation Containing a High Lipid Content
Authors: Thomsen Birgitte R. , Taylor Richard , Madsen Robert , Hyldig Grethe , Blenkiron Peter , Jacobsen Charlotte 
Published: March 2018

AbstractSeveral studies have demonstrated that lipid oxidation often occurs in topical skin formulations which can affect product odor (both positively and negatively). Furthermore, odor detection threshold values and odor descriptors of identified volatile oxidation products in cleansing and skin cream formulation prototypes were recently determined by a trained sensory panel at the Technical University of Denmark in the Division of Food Technology. In this study, we investigated lipid oxidation in a prototype skin cream formulation as well as in selected cosmetic skin care raw materials. Lipid oxidation was measured regularly over a six‐month period for the product and over a three‐month period for the raw materials by headspace gas chromatography–mass spectrometry. The volatile compound present in the highest initial concentration, and which increased most during storage, was 3‐methyl‐1‐butanol (medicinal, chemical/cleaning agent odor), and its formation was linked to the raw material isoamyl p‐methoxycinnamate. The odor character of the product after storage was assessed and informally deemed acceptable for consumer usage and typical of topical dermocosmetic products. A potential pathway for its formation was also identified. In addition, the concentrations of several well‐known lipid oxidation products increased during storage and were suggested to originate primarily from rice bran wax, which oxidized more readily than other raw materials due to its unsaturated nature.
Friction‐induced electroactive β polymorph of poly(vinylidene fluoride)
Authors: Xu Fanglin , Xin Yuanshi , Li Tongsheng 
Published: March 2018

ABSTRACTPoly(vinylidene fluoride) (PVDF) has been widely used in electric devices due to electroactive β polymorph. In this article, we probe the formation of β phase under friction by spectroscopy and thermal analysis. During continuous friction, entire sliding of PVDF is identified with two regimes, i.e., running‐in and steady‐state. At initial running‐in period, friction surfaces are dominated by plastic strain, which leads to striking formation of β phase from α polymorph (α→β). Subsequently, melting‐flow domains almost cover friction surfaces at steady‐state. Thus, formation of β crystal is correspondingly induced by shear crystallization. Nevertheless, β‐crystal content at steady‐state is lower than that at running‐in. With sliding proceeding, moreover, β‐crystal content exhibits a gradually decreasing tendency, attributed to rising surface temperature. Besides, the friction‐induced β phase is further confirmed by evaluation of wear debris. Overall, friction plays a crucial role as to the formation of β phase. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46395.