bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of the Six-item Female Sexual Function Index in Middle-Aged Brazilian Women
Authors: Dall'Agno Mona Lúcia , Ferreira Charles Francisco , Ferreira Fernanda Vargas , Pérez-López Faustino R. , Wender Maria Celeste Osório 
Published: July 2019

Objective To validate the six-item female sexual function index (FSFI-6) in middle-aged Brazilian women.
Methods Cross-sectional observational study, involving 737 (premenopausal n = 117, perimenopausal n = 249, postmenopausal n = 371) Brazilian sexually active women, aged between 40 and 55 years, not using hormonal contraceptive methods. The Brazilian FSFI-6 was developed from the translation and cultural adaptation of the Portuguese FSFI-6 version. The participants completed a general questionnaire, the FSFI-6, and the menopause rating scale (MRS). The validation was performed by AMOS 16.0 software (SPSS, Inc., Chicago, IL, USA) for a confirmatory factor analysis (CFA). The chi-square of degrees of freedom (χ2/df), the comparative fit index (CFI), the Tucker-Lewis index (TLI) and the root-mean-square error of approximation (RMSEA) were used as indices of goodness of fit. Cronbach α coefficient was used for internal consistency.
Results The process of cultural adaptation has not altered the Brazilian FSFI-6, as compared with the original content. The CFA for the FSFI-6 score showed an acceptable fit (χ2/df = 3.434, CFI = 0.990, TLI = 0.980, RMSEA = 0.058, 90% confidence interval (90%CI) = 0.033–0.083, p ≤ 0.001) and a good reliability was established in FSFI-6 and MRS (Cronbach α = 0.840 and = 0.854, respectively). In addition, 53.5% of the sample had low sexual function.
Conclusion The FSFI-6 was translated and adapted to the Brazilian culture and is a consistent and reliable tool for female sexual dysfunction screening in Brazilian middle-aged women.
Evaluation of Different Seeding Methods for Cell-Seeded Collagen Matrix-Supported Autologous Chondrocyte Transplantation
Authors: Viganò Marco , Lugano Gaia , Colombini Alessandra , De Luca Paola , Perucca Orfei Carlotta , Ragni Enrico , de Girolamo Laura 
Published: July 2019

Purpose The aim of the present study was to evaluate different methods for the intraoperative seeding of chondrocytes on commercially available collagen I/III matrix, in the context of cell-seeded collagen matrix-supported autologous chondrocyte transplantation (ACT-CS).
Methods Human chondrocytes were enzymatically isolated from cartilage portion of discarded femoral heads of patients who underwent total hip replacement. Chondrocytes were cultured until passage 3, and then used for the experiments. The cells (5.0 × 105) were suspended in two different volumes, 75 and 250 µL, and seeded on a matrix sample with a surface of 1 cm2 by means of a micropipette. Moreover, the direct immersion of the matrix in the cell suspension was evaluated as a possible protocol for chondrocyte seeding. Cell adhesion was allowed for 10, 30, or 60 minutes in all samples before evaluation.
Results Data showed that the seeding time did not affect cell viability and distribution, but there was a great difference between the two volumes of injection. In fact, the use of 75 µL significantly reduced cell viability with respect to both 250 µL seeding volume and the immersion protocol. Indeed, cell distribution resulted homogeneous in the samples seeded with the larger volume and with the immersion protocol.
Conclusion The use of 250 µL/cm2 volume or the immersion protocol for 10 minutes are valuable methods for chondrocyte seeding on collagen matrix in an intraoperative scenario.
Clinical Relevance The protocol of chondrocyte seeding in ACT-CS is extremely variable among available literature reports. Chondrocytes adhesion to the matrix represents a crucial step in this methodology, and the present study provides in vitro indication for the choice of the seeding protocol in the context of ACT-CS.
The Risk Assessment and Prediction Tool (RAPT) after Hip and Knee Replacement: A Systematic Review
Authors: Sconza Cristiano , Respizzi Stefano , Grappiolo Guido , Monticone Marco 
Published: July 2019

Purpose The Risk Assessment and Prediction Tool (RAPT) is an interesting instrument for predicting the discharge destination and length of stay (LOS) for patients after hip or knee arthroplasty. The aim of this review is to describe its predictive ability, current utilization, and future prospects through the analysis of scientific literature.
Methods The databases of PubMed, Web of Sciences, Cochrane Library, and Pedro were searched for English studies on RAPT prediction capacity. Only original prospective or retrospective articles that analyze specifically the use of RAPT were included, whereas those concerned with other preoperative prediction tools or those only considering other aspects of recovery after joint replacements were excluded.
Results A total of 27 references were retrieved, and 8 studies were selected. All analyzed studies demonstrated that RAPT could reduce LOS and accurately predict discharge disposition especially for high- and low-risk patients. In the intermediate risk category, a targeted intensive postoperative rehabilitation program has demonstrated good results in reducing the uncertain outcome.
Conclusion Although contrarily to many of the other scores, the RAPT has been validated in multiple countries with relatively similar results between different institutions; however, its validity has yet to be tested and adapted in every nation context. Further studies confirming the predictive accuracy of RAPT at other institutions are needed as well as studies assessing the effect of using RAPT to identify patients for targeted interventions in terms of LOS, discharge disposition, clinical outcomes, and financial impact.
Level of Evidence This is a level IV, systematic review of level III and IV study.
Assessment of Polymorphism of the VDR Gene and Serum Vitamin D Values in Gestational Diabetes Mellitus
Authors: Siqueira Thais Walverde , Araujo Júnior Edward , Mattar Rosiane , Daher Silvia 
Published: July 2019

Objective To evaluate the relationship between vitamin D receptor (VDR) gene polymorphism (FokI [rs10735810]) and serum vitamin D concentration in gestational diabetes mellitus (GDM).
Methods A prospective case-control study that recruited healthy pregnant women (control group) (n = 78) and women with GDM (GDM group) (n = 79), with no other comorbidities. Peripheral blood samples were collected in the 3rd trimester of gestation, and all of the pregnant women were followed-up until the end of the pregnancy and the postpartum period. Serum vitamin D concentrations were measured by high-performance liquid chromatography (HPLC). For genomic polymorphism analysis, the genomic DNA was extracted by the dodecyltrimethylammonium bromide/cetyltrimethylammonium bromide (DTAB/CTAB) method, and genotyping was performed by the polymerase chain reaction – restriction fragment length polymorphism (PCR-RFLP) technique, using the restriction enzyme FokI. The Student-t, Mann-Whitney, chi-squared, and Fischer exact tests were used for the analysis of the results.
Results There was no significant difference between the pregnant women in the control and GDM groups regarding serum vitamin D levels (17.60 ± 8.89 ng/mL versus 23.60 ± 10.68 ng/mL; p = 0.1). Also, no significant difference was detected between the FokI genotypic frequency when the 2 groups were compared with each other (p = 0.41).
Conclusion There was no association between the FokI polymorphism and the development of GDM, nor was there any change in serum vitamin D levels in patients with GDM.
TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages
Authors: Li Yang , James Sharmy J. , Wyllie David H. , Wynne Claire , Czibula Agnes , Bukhari Ahmed , Pye Katherine , Bte Mustafah Seri Musfirah , Fajka-Boja Roberta , Szabo Eniko , Angyal Adrienn , Hegedus Zoltan , Kovacs Laszlo , Hill Adrian V. S. , Jefferies Caroline A. , Wilson Heather L. , Yongliang Zhang , Kiss-Toth Endre 
Published: July 2019

Significance
Activators of interferons have received a great deal of interest in recent decades, both due to the central role they play in host defense against a range of pathogens, as well as the now well-recognized importance of dysregulated interferon activation/signaling in the pathogenesis of a number of highly prevalent and hard-to-treat diseases, such as systemic lupus erythematosus (SLE). Therefore, novel regulators of interferon activation are being sought as they may provide better targets to treat these diseases. We report the discovery of TMEM203 as an SLE-associated gene and a regulator of ligand-dependent activation of interferon production via STING. Thus, our work could form the basis of a novel therapeutic strategy for the treatment of interferonopathies, including SLE.
Rotation of polarization in the gravitational field of a laser beam—Faraday effect and optical activity
Authors: Schneiter Fabienne , Rätzel Dennis , Braun Daniel 
Published: July 2019

Abstract
We investigate the rotation of the polarization of a light ray propagating in the gravitational field of a circularly polarized laser beam. The rotation consists of a reciprocal part due to gravitational optical activity, and a non-reciprocal part due to the gravitational Faraday effect. We discuss how to distinguish the two effects: letting light propagate back and forth between two mirrors, the rotation due to gravitational optical activity cancels while the rotation due to the gravitational Faraday effect accumulates. In contrast, the rotation due to both effects accumulates in a ring cavity and a situation can be created in which gravitational optical activity dominates. Such setups amplify the effects by up to five orders of magnitude, which however is not enough to make them measurable with state of the art technology. The effects are of conceptual interest as they reveal gravitational spin–spin coupling in the realm of classical general relativity, a phenomenon which occurs in perturbative quantum gravity.
Roadmap on photonic, electronic and atomic collision physics: I. Light–matter interaction
Authors: Ueda Kiyoshi , Sokell Emma , Schippers Stefan , Aumayr Friedrich , Sadeghpour Hossein , Burgdörfer Joachim , Lemell Christoph , Tong Xiao-Min , Pfeifer Thomas , Calegari Francesca , Palacios Alicia , Martin Fernando , Corkum Paul , Sansone Giuseppe , Gryzlova Elena V , Grum-Grzhimailo Alexei N , Piancastelli Maria Novella , Weber Peter M , Steinle Tobias , Amini Kasra , Biegert Jens , Berrah Nora , Kukk Edwin , Santra Robin , Müller Alfred , Dowek Danielle , Lucchese Robert R , McCurdy C William , Bolognesi Paola , Avaldi Lorenzo , Jahnke Till , Schöffler Markus S , Dörner Reinhard , Mairesse Yann , Nahon Laurent , Smirnova Olga , Schlathölter Thomas , Campbell Eleanor E B , Rost Jan-Michael , Meyer Michael , Tanaka Kazuo A 
Published: July 2019

AbstractWe publish three Roadmaps on photonic, electronic and atomic collision physics in order to celebrate the 60th anniversary of the ICPEAC conference. In Roadmap I, we focus on the light–matter interaction. In this area, studies of ultrafast electronic and molecular dynamics have been rapidly growing, with the advent of new light sources such as attosecond lasers and x-ray free electron lasers. In parallel, experiments with established synchrotron radiation sources and femtosecond lasers using cutting-edge detection schemes are revealing new scientific insights that have never been exploited. Relevant theories are also being rapidly developed. Target samples for photon-impact experiments are expanding from atoms and small molecules to complex systems such as biomolecules, fullerene, clusters and solids. This Roadmap aims to look back along the road, explaining the development of these fields, and look forward, collecting contributions from twenty leading groups from the field.
Visualization of gold fiducial markers in the prostate using phase-cycled bSSFP imaging for MRI-only radiotherapy
Authors: Shcherbakova Yulia , Bartels Lambertus W , Mandija Stefano , Beld Ellis , Seevinck Peter R , van der Voort van Zyp Jochem R N , Kerkmeijer Linda G W , Moonen Chrit T W , Lagendijk Jan J W , van den Berg Cornelis A T 
Published: July 2019

Abstract
In this work, we present a new method for visualization of fiducial markers (FMs) in the prostate for MRI-only radiotherapy with a positive contrast directly at the MR console. The method is based on high bandwidth phase-cycled balanced steady-state free precession (bSSFP) sequence, which is available on many clinical scanners, does not require any additional post-processing or software, and has a higher signal-to-noise (SNR) compared to conventional gradient-echo (GE) imaging. Complex phase-cycled bSSFP data is acquired with different RF phase increment settings such that the manifestation of the artifacts around FMs in the acquired complex images is different for each dynamic acquisition and depends on the RF phase increment used.
First, we performed numerical simulations to investigate the complex-valued phase-cycled bSSFP signal in the presence of a gold FM, and to investigate the relation of the true physical location of the FM with the geometrical manifestation of the artifacts. Next, to validate the simulations, we performed phantoms and in vivo studies and compared the experimentally obtained artifacts with those predicted in simulations. The accuracy of the method was assessed by comparing the distances between the FM’s centers and the center of mass of FMs system measured using phase-cycled bSSFP MR images and using reference CT (or MRI-only) images.
The results show accurate (within 1 mm) matching of FMs localization between CT and MR images on five patients, proving the feasibility of in vivo FMs detection on MR images only. The FMs show a positive contrast with respect to the prostate background on real/imaginary phase-cycled bSSFP images, which was confirmed by simulations.
The proposed method facilitates robust FMs visualization with positive contrast directly at the MR console, allowing RT technicians to obtain immediate feedback on the anticipated feasibility of accurate FMs localization while the patient is being scanned.
Symmetry breaking in molecular artificial graphene
Authors: Yan Linghao , Hua Muqing , Zhang Qiushi , Ngai Tsz Ue , Guo Zesheng , Wu Tsz Chun , Wang Tong , Lin Nian 
Published: July 2019

Abstract
Symmetry breaking in graphene has profound impacts on its physical properties. Here we emulate symmetry breaking in artificial graphene systems by assembling coronene molecules on a Cu(111) surface. We apply two strategies: (1) differentiating the on-site energy of two sublattices of a honeycomb lattice and (2) uniaxially compressing a honeycomb lattice. The first one breaks the inversion symmetry while the second one merges the Dirac cones. The scanning tunneling spectroscopy shows that in both cases the local density of states undergo characteristic changes. Muffin-tin simulations reveal that the observed changes are associated with a band gap opened at the Dirac point. Furthermore, we propose that using larger molecules or molecules strongly scattering the surface state electrons can induce an indirect gap.
Magneto-optical conductance of Kane fermion gas in low frequencies
Authors: Luo Xi , Chen Yu-Ge , Yu Yue 
Published: July 2019

Abstract
Kane fermion is the counterpart of the Dirac fermion with pseudospin-1. Due to the existence of a bunch of gapless modes associated with Landau levels, the magnetic transport property of Kane fermion gas is very different from that of the Dirac semimetal. We calculate the magneto-optical conductance of the Kane fermion gas. We find that these gapless modes will contribute to a series of resonant peaks in low frequencies. We find that these peaks can explain the low frequency absorbance spectrum in a recent experiment for the Kane fermion material Hg1−x
Cd
x
Te.
Generation of relativistic high-order-mode laser pulse using plasma waveguide
Authors: Yu D Y , Zou D B , Yu M Y , Yu T P , Yin Y , Shao F Q , Zhuo H B , Zhou C T , Ruan S C 
Published: July 2019

Abstract
An all-optical method for generating ultra-intense high-order-mode light pulse is investigated with three-dimensional particle-in-cell simulation. We find that the conversion from a short intense circularly polarized incident Gaussian laser pulse into a transverse magnetic (TM) mode occurs as it propagates into a micro plasma waveguide. The strength of the longitudinal electric field of the excited TM modes can be almost two orders of magnitude higher than that of the original laser. The simulation results show that, for the lower-order modes, the trapped electrons lead to their revolving transverse structures. A linear plasma waveguide model is presented to predict the mode pattern and intensity of the longitudinal electric fields, which are in excellent agreement with those in the simulations. Relativistic-intense high-order-mode light can be useful for many applications, including accelerating charged particles to high energies.
Quantum process identification: a method for characterizing non-markovian quantum dynamics
Authors: Bennink Ryan S , Lougovski Pavel 
Published: July 2019

Abstract
Established methods for characterizing quantum information processes do not capture non-Markovian (history-dependent) behaviors that occur in real systems. These methods model a quantum process as a fixed map on the state space of a predefined system of interest. Such a map averages over the system’s environment, which may retain some effect of its past interactions with the system and thus have a history-dependent influence on the system. Although the theory of non-Markovian quantum dynamics is currently an active area of research, a systematic characterization method based on a general representation of non-Markovian dynamics has been lacking. In this article we present a systematic method for experimentally characterizing the dynamics of open quantum systems. Our method, which we call quantum process identification (QPI), is based on a general theoretical framework which relates the (non-Markovian) evolution of a system over an extended period of time to a time-local (Markovian) process involving the system and an effective environment. In practical terms, QPI uses time-resolved tomographic measurements of a quantum system to construct a dynamical model with as many dynamical variables as are necessary to reproduce the evolution of the system. Through numerical simulations, we demonstrate that QPI can be used to characterize qubit operations with non-Markovian errors arising from realistic dynamics including control drift, coherent leakage, and coherent interaction with material impurities.
Interpretation of suprathermal emission at deuteron cyclotron harmonics from deuterium plasmas heated by neutral beam injection in the KSTAR tokamak
Authors: Chapman B. , Dendy R.O. , Chapman S.C. , McClements K.G. , Yun G.S. , Thatipamula S.G. , Kim M.H. 
Published: July 2019

Abstract
Intense bursts of suprathermal radiation, with spectral peaks at frequencies corresponding to the deuteron cyclotron frequency in the outer midplane edge region, are often detected from deuterium plasmas in the KSTAR tokamak that are heated by tangential neutral beam injection (NBI) of deuterons at 100 keV. Identifying the physical process by which this deuterium ion cyclotron emission (ICE) is generated, typically during the crash of edge localised modes, assists the understanding of collective energetic ion behaviour in tokamak plasmas. In the context of KSTAR deuterium plasmas, it is also important to distinguish deuterium ICE from the ICE at cyclotron harmonics of fusion-born protons examined by Chapman et al (2017 Nucl. Fusion
57 124004; 2018 Nucl. Fusion
58 096027). We use particle orbit studies in KSTAR-relevant magnetic field geometry, combined with a linear analytical treatment of the magnetoacoustic cyclotron instability (MCI), to identify the sub-population of freshly ionised NBI deuterons that is likely to excite deuterium ICE. These deuterons are then represented as an energetic minority, together with the majority thermal deuteron population and electrons, in first principles kinetic particle-in-cell (PIC) computational studies. By solving the Maxwell–Lorentz equations directly for hundreds of millions of interacting particles with resolved gyro-orbits, together with the self-consistent electric and magnetic fields, the PIC approach enables us to study the collective relaxation of the energetic deuterons through the linear phase and deep into the saturated regime. The Fourier transform of the excited fields displays strong spectral peaks at multiple successive deuteron cyclotron harmonics, mapping well to the observed KSTAR deuterium ICE spectra. This outcome, combined with the time-evolution of the energy densities of the different particle populations and electric and magnetic field components seen in the PIC computations, supports our identification of the driving sub-population of NBI deuterons, and the hypothesis that its relaxation through the MCI generates the observed deuterium ICE signal. We conclude that the physical origin of this signal in KSTAR is indeed distinct from that of KSTAR proton ICE, and is in the same category as the NBI-driven ICE seen notably in the TFTR tokamak and LHD heliotron–stellarator plasmas. ICE has been proposed as a potential passive diagnostic of energetic particle populations in ITER plasmas; this is assisted by clarifying and extending the physics basis of ICE in contemporary magnetically confined plasmas.
A comparative study of hybrid simulation and dynamical substructuring system schemes for shake table tests
Authors: Enokida Ryuta 
Published: July 2019

Abstract
In shaking table experiments, the dynamics of the shake table is strongly affected by a specimen to be tested, particularly when the specimen is very heavy. This is also the case when substructuring experiments are implemented by the shaking tables. This study numerically examines two substructuring schemes applied in shaking table experiments. Hybrid simulation scheme, which is commonly used in substructuring experiments, directly uses the output of the numerical substructure as the input to the physical substructure. Dynamical substructuring system (DSS) scheme, which requires more complicated control design, determines the control input to minimize control error obtained by outputs of numerical and physical substructures. This study has found that, in shaking experiments, the stability of the hybrid simulation scheme is very sensitive to a pure time delay. It is also found that DSS scheme can provide much higher stability margin against the pure time delay than the hybrid simulation scheme. The effort to rather complicated controller design of DSS scheme will be rewarded at actual control practices.