bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Validation of a Pragmatic Electronic Phenotype for CKD
Authors: Norton Jenna M. , Ali Kaltun , Jurkovitz Claudine T. , Kiryluk Krzysztof , Park Meyeon , Kawamoto Kensaku , Shang Ning , Navaneethan Sankar D. , Narva Andrew S. , Drawz Paul 
Published: August 2019

Background and objectives
Poor identification of individuals with CKD is a major barrier to research and appropriate clinical management of the disease. We aimed to develop and validate a pragmatic electronic (e-) phenotype to identify patients likely to have CKD.

Design, setting, participants, & measurements
The e-phenotype was developed by an expert working group and implemented among adults receiving in- or outpatient care at five healthcare organizations. To determine urine albumin (UA) dipstick cutoffs for CKD to enable use in the e-phenotype when lacking urine albumin-to-creatinine ratio (UACR), we compared same day UACR and UA results at four sites. A sample of patients, spanning no CKD to ESKD, was randomly selected at four sites for validation via blinded chart review.

Results
The CKD e-phenotype was defined as most recent eGFR <60 ml/min per 1.73 m2 with at least one value <60 ml/min per 1.73 m2 >90 days prior and/or a UACR of ≥30 mg/g in the most recent test with at least one positive value >90 days prior. Dialysis and transplant were identified using diagnosis codes. In absence of UACR, a sensitive CKD definition would consider negative UA results as normal to mildly increased (KDIGO A1), trace to 1+ as moderately increased (KDIGO A2), and ≥2+ as severely increased (KDIGO A3). Sensitivity, specificity, and diagnostic accuracy of the CKD e-phenotype were 99%, 99%, and 98%, respectively. For dialysis sensitivity was 94% and specificity was 89%. For transplant, sensitivity was 97% and specificity was 91%.

Conclusions
The CKD e-phenotype provides a pragmatic and accurate method for EHR-based identification of patients likely to have CKD.
Repairing earth dam drainage systems
Authors: Krutov Denis A. 
Published: August 2019

Introduction: when reconstructing or overhauling dams, great attention should be paid to drainage systems as the most critical components of the installations. The article describes the typical malfunctions of earth dam pipe drainages. The research considers geological and hydrogeological features that were not taken into account when developing projects.
Materials and methods: control and measuring instrumentation (piezometer network), full-scale experiments on disabling pipe drainage and mathematical modelling were used as the filtration regime research methods.
Results: analysis of the hydrogeological features of the base of the right-bank floodplain dam of the Nizhegorodskaya hydroelectric power plant and field filtration observations revealed a strong drainage effect of the base on the filtration flow at several areas of the dam body. At the other areas, a high groundwater level position at the dam downstream and its outlet into the pipe drainage at the downstream were recorded. Substantiated by filtration calculations, the proposed repair of the drainage system consisted in designing open drainage along the dam axis and backfilling the territory at the downstream by 2.0 m that excludes impoundment of the territory without the pipe drainage.
Conclusions: the following engineering solutions can be recommended for repairing earth dam drainage systems: construction of backfill drainage trenches in the dam downstream, new pipe drainage at higher elevations or an open drainage channel in solid reinforced concrete arranged along the axis of the dam. The proposed version of the pipe drainage repair provides for constructing an open drainage channel in solid reinforced concrete on a reverse filter with an arrangement of gravel-filled asbestos-cement pipes in the dam slopes and bottom. Such a design solution allows repairing the drainage system without dewatering and, if necessary, completely refusing the existing pipe drainage.
Machine Learning in Orthodontics: Introducing a 3d Auto-segmentation and Auto-landmark Finder of Cbct Images To Assess Maxillary Constriction in Unilateral Impacted Canine patients
Authors: Chen Si , Wang Li , Li Gang , Wu Tai-Hsien , Diachina Shannon , Tejera Beatriz , Kwon Jane Jungeun , Lin Feng-Chang , Lee Yan-Ting , Xu Tianmin , Shen Dinggang , Ko Ching-Chang 
Published: August 2019

ABSTRACT

Objectives
To (1) introduce a novel machine learning method and (2) assess maxillary structure variation in unilateral canine impaction for advancing clinically viable information.

Materials and Methods
A machine learning algorithm utilizing Learning-based multi-source IntegratioN frameworK for Segmentation (LINKS) was used with cone-beam computed tomography (CBCT) images to quantify volumetric skeletal maxilla discrepancies of 30 study group (SG) patients with unilaterally impacted maxillary canines and 30 healthy control group (CG) subjects. Fully automatic segmentation was implemented for maxilla isolation, and maxillary volumetric and linear measurements were performed. Analysis of variance was used for statistical evaluation.

Results
Maxillary structure was successfully auto-segmented, with an average dice ratio of 0.80 for three-dimensional image segmentations and a minimal mean difference of two voxels on the midsagittal plane for digitized landmarks between the manually identified and the machine learning–based (LINKS) methods. No significant difference in bone volume was found between impaction ([2.37 ± 0.34] 104 mm3) and nonimpaction ([2.36 ± 0.35] 104 mm3) sides of SG. The SG maxillae had significantly smaller volumes, widths, heights, and depths (P &lt; .05) than CG.

Conclusions
The data suggest that palatal expansion could be beneficial for those with unilateral canine impaction, as underdevelopment of the maxilla often accompanies that condition in the early teen years. Fast and efficient CBCT image segmentation will allow large clinical data sets to be analyzed effectively.
Sistema de prescrição eletrônica em uma empresa de home care: percepção de médicos e enfermeiros
Authors: Santos Lucieno De Moura , Falk James Anthony 
Published: August 2019

A prescrição médica informatizada, ou prescrição eletrônica, surgiu como meio de mudança na prática médica, onde na adoção dessa tecnologia, vislumbra-se a capacidade do profissional de associá-la no seu dia-a-dia para atingir melhorias para o paciente, para a instituição e para si. O estudo teve por objetivo avaliar a percepção de médicos e enfermeiros sobre a utilização do sistema de prescrição médica eletrônica em uma empresa de home care na cidade do Recife-PE. Trata-se de uma pesquisa de campo com abordagem quantitativa, de natureza exploratória e descritiva. Para a coleta de dados foi elaborado um questionário com respostas apresentadas por uma escala de Likert de cinco possibilidades. Os resultados obtidos foram analisados no software Statistical Package for the Social Sciences (SPSS). Neste, foram feitos os testes de Levine para igualdade de variâncias e o teste t para igualdade das médias. Todos apresentaram significância estatística, pois o valor de p foi menor que 0,005. Houve evidências estatísticas, ao nível de 5%, de diferenças entre o antes e depois para todas as variáveis. Médicos e enfermeiros perceberam o impacto positivo com a utilização da prescrição médica eletrônica nas variáveis segurança do paciente e da prescrição, bem como a redução de erros de prescrição. Onde estas foram também as mais citadas por eles.Palavras-chave: Tecnologia da informação; Prescrição médica; Assistência domiciliar. ABSTRACTThe computerized medical prescription, or electronic prescription, newcomer as a means of attention in the medical hour, where the technology is found, is a capacity of the professional to associate with the attention for the patient, the institution and for themselves. The purpose of this study was to evaluate the medical and nursing care about the use of the medical prescription system in a home care company in the city of Recife-PE. It is a field research with a quantitative approach, exploratory and descriptive in nature. For a data collection, a file with the answers of a Likert scale of five possibilities was elaborated. The results obtained were without software Statistical Package for Social Sciences (SPSS). In this, the Levine tests were made for equality of variables and the test of equality of averages. All values were significant, as the p value was lower than 0.005. The chance to play at the 5% level, to differentiate between before and after for all variables. Doctors and doctors have positively warned about the use of the medical prescription with the indication of the medical prescription, as well as the reduction of prescription errors. Where these were also more cited by them.Keywords: Information technology; Medical prescription; Home care.
POLA ASUH ORANG TUA DAN KENAKALAN REMAJA
Authors: Nur Utami Adristinindya Citra , Raharjo Santoso Tri 
Published: August 2019

Di era ini, kenakalan remaja sudah sangat sering terjadi. Kenakalan remaja adalah suatu perbuatan yang melanggar norma aturan dan tata hukum masyarakat yang di lakukan pada usia remaja atau transisi dari masa anak-anak ke dewasa. Perilaku yang menyimpang dari norma hukum pidana yang dilakukan oleh remaja merupakan problema yang sering terjadi pada remaja baik di lingkungan keluarga, sekolah, maupun masyarakat. Jika tidak ditangani dengan baik, kenakalan remaja dapat berubah menjadi perilaku criminal dan dapat membawa remaja tersebut ke dalam penjara. Bila ditelusuri secara mendalam perkembangan kejahatan remaja banyak di pengaruhi dari kehidupan keluarga dan masyarakat. Keluarga memiliki peranan penting dalam mencegah kenakalan remaja. Salah satu cara yang dapat dilakukan keluarga untuk mencegah kenakalan remaja adalah dengan menggunakan pola asuh yang tepat. Pola asuh yang digunakan oleh orang tua memberikan pengaruh pada perilaku anak. Menurut hasil assessment di LPKA Sukamiskin, Bandung, ditemukan keterkaitan atau pengaruh antara pola asuh orang tua terhadap kenakalan dan perilaku criminal yang dilakukan oleh remaja. In this era, juvenile delinquency is very common. Juvenile delinquency is an act that violates the norms and rules of law of society that are done in adolescence or the transition from childhood to adulthood. Behavior that deviates from criminal law norms committed by adolescents is a problem that often occurs in adolescents both in the family, school, and society. If not handled properly, juvenile delinquency can turn into criminal behavior and can bring the teenager into prison. When traced in depth the development of juvenile crime is influenced by family life and society. Family has an important role in preventing juvenile delinquency. One way that families can do to prevent juvenile delinquency is to use proper parenting. Parenting is used by parents to influence children's behavior. According to the results of the assessment at Sukamiskin LPKA, Bandung, it was found that the relationship between parents' parenting and delinquency behavior was carried out by teenagers.
Experiments on Temperature Control Using On-Off Algorithm Combined with PID Algorithm
Authors: Dulău Mircea 
Published: August 2019

Abstract
The paper presents an automated system for the temperature control using a PIC microcontroller, a digital temperature sensor with I2C and a MOSFET as actuator. The control strategy is a proportional-integrative one, preceded by an on-off algorithm. The most important data is presented on a graphical interface. In order to send the parameters of the process and the command states to the computer, the serial communication is used.
Fracture zones detection for groundwater exploration integrating Resistivity Profiling and Very Low Frequency electromagnetic methods (Errachidia basin, Morocco)
Authors: Ait Bahammou Youssef , Benamara Ahmed , Ammar Abdellah , Dakir Ibrahim 
Published: August 2019

Abstract
Resistivity Profiling and Very Low Frequency (VLF) electromagnetic methods were introduced to study fracture zones detection in Zaouia Jdida locality, within the Errachidia basin. The Horizontal Profiling was conducted in Wenner-α array, with AB = 300 m and profile lines oriented NW–SE and NE–SW. The resistivity measurements were taken using MAE advanced geophysics instruments. The VLF profiles were implanted with the length reaches 1000 m and profile lines oriented in NE–SW direction. The VLF measurements were collected using T-VLF iris instrument and the data filtering was done using KHFFILT software. Two filters, Karous-Hjelt and Fraser, were applied to the real component of the secondary electromagnetic field. The qualitative interpretation of resistivity results, showed the presence of subsurface targets; fracture zones were detected at 70m, 240m and 450m positions along the profile P1, at 180m, 340m and 450m positions from the profile P2. The semi-quantitative interpretation of VLF results revealed the presence of two principal fracture zones at L3 and L5 locations, oriented NW–SE, at a depth range of 30 m to 60 m. The VLF anomaly observed at L3 location is confirmed by the resistivity measurements from the profile P1 (at 70m station). The identified fractures represent the potential zones for groundwater supply and then will have an implication on storage and movement of groundwater in the prospect area.
High-precision local gravity survey along planned motorway tunnel in the Slovak Karst
Authors: Zahorec Pavol , Papčo Juraj , Vajda Peter , Szabó Stanislav 
Published: August 2019

Abstract
Results from a detailed gravity survey realized along the planned highway tunnel in the karstic area of Slovak Karst in the eastern Slovakia are presented. Detailed gravity profiles crossed an area of rugged topography, therefore the terrain corrections played a crucial role in the gravity data processing. The airborne laser scanning technique (LiDAR) was used in order to compile a high-resolution digital terrain model (DTM) of the surrounding area and to calculate terrain corrections properly. The difference between the Bouguer anomalies calculated with an available nationwide DTM and those with new LiDAR-based model can be significant in some places as it is presented in the paper. A new method for Bouguer correction density analysis based on surface data is presented. Special underground gravity measurements in the existing nearby railway tunnel were also conducted in order to determine the mean density of the topographic rocks. The Bouguer anomalies were used to interpret lithological contacts and tectonic/karstic discontinuities.
Requisite Skill Availability and Multinational Corporations Locational Strategies in Nigeria
Authors: Akinbola Olufemi Amos , Kowo Solomon Akpoviroro , Ojo Olugbenga Abiola 
Published: August 2019

Abstract

Research Background: Unemployment has been a major inhibitor of growth and development in Nigeria and it has been a perpetual problem that has proven insurmountable despite various governmental administration interventions and commercial policies to encourage the influx of multinational corporations and foreign direct investment. As such, this study examined the effect of requisite skill availability (RSA) on multinational Corporations locational strategy (LS) as there has always been skill mismatch inhibiting employability.

Research Methodology: The study adopted a cross sectional research design and considered 5 multinational corporations in Nigeria by a random sampling technique. The statistical tools used included multiple regressions and a Correlation analysis through SPSS.

Results: The results indicated (RSA) has a significant positive relationship with locational strategy (at p = 0.004). It was also observed that other controlling variables as trade facilitation, foreign ownership policy and structural infrastructural availability also has a significant positive effect.

Novelty: The study recommends that; the government should provide an education and personal development platform that would make its citizenry employable based on the skills that are needed by multinational corporations to be localized in the country.
The Theoretical Model of Polish Housing Policy between 2002 and 2016
Authors: Kamiński Maciej 
Published: August 2019

Abstract

Research background: This paper attempts to introduce the concept of Polish housing policy and define its course.

Purpose: The main aim of the paper is to attribute the theoretical model of Polish housing policy and its goals and summarize the practical instruments and programs implemented between 2002 and 2016 to try to answer the question in what way the state was helping households to fulfil housing needs.

Research methodology: The research method used in the paper was a query of Polish and foreign literature of housing policy models, goals and instruments in the theoretical part, in the practical part (main research) is the monograph analysis of Polish housing policy between 2002 and 2016 including: housing resource, housing supply and change of their structure in the examined timeline, availability of apartments, supply of mortgages and connections with the availability of apartments and macroeconomic situation measured by the yearly GDP per capita.

Results: Theoretical and practical solutions were made. Polish housing policy can be defined as a wide ranging selective model according to Ghekiere (2009) division, the empirical analysis of the adopted solutions risks – marginalization of social housing and substantial impact of the financial sector (banking and mortgages) on housing which may be negative in the case of an economic crisis.

Novelty: The value of this paper is a contribution to the debate on defining a theoretical model of housing policy and an explanation of the changes in housing in Poland from 2002–2016.
Long-Term Equity Performance in Poland – Searching for Answers with the Calendar-Time Portfolio Approach
Authors: Lizińska Joanna , Czapiewski Leszek 
Published: August 2019

Abstract

Research background: The study examines the performance of companies that are going public with equity issuance (IPO) in Poland.

Purpose: Some scholars argue that the buy-and-hold strategy that has been quite widely used suffers from cross correlation and the “bad model” problem. Hence, the calendar-time portfolio approach is used to extend the methodology.

Research Methodology: The empirical procedure is two-step. At the beginning, we calculate an average abnormal return for the portfolio of IPOs firms. The portfolio is rebalanced each month. Next, the risk-adjusted performance is measured by regressing returns on a multifactor time-series regression model. We employ the Fama-French (1993) three-factor model and CAPM for the robustness check.

Results: In a sample of IPOs listed on the Warsaw Stock Exchange, we find negative and highly significant abnormal returns. Alphas are statistically significant in all of the Fama-French regressions and in most of the cases for CAPM.

Novelty: This paper discusses the puzzle of the long-term equity performance of initial public offerings (IPOs) using the calendar-time portfolio approach. Our results point to the economic and statistical significance of long-term IPO underperformance.
Prediction of 24-hour milk yield and composition in dairy cows from a single part-day yield and sample
Authors: McParland S. , Coughlan B. , Enright B. , O’Keeffe M. , O’Connor R. , Feeney L. , Berry D.P. 
Published: August 2019

Abstract
The objective was to evaluate the accuracy of predicting 24-hour milk yield and composition from a single morning (AM) or evening (PM) milk weight and composition. A calibration dataset of 37,481 test-day records with both AM and PM yields and composition was used to generate the prediction equations; equations were validated using 4,644 test-day records. Prediction models were developed within stage of lactation and parity while accounting for the inter-milking time interval. The mean correlation between the predicted 24-hour yields and composition of milk, fat and protein and the respective actual values was 0.97 when based on just an AM milk yield and composition with a mean correlation of 0.95 when based on just a PM milk yield and composition. The regression of predicted 24-hour yield and composition on the respective actual values varied from 0.97 to 1.01 with the exception of 24-hour fat percentage predicted from a PM sample (1.06). A single AM sample is useful to predict 24-hour milk yield and composition when the milking interval is known.
Cervical Spine Spondylitis with an Epidural Abscess in a Patient with Brucellosis: A Case Report
Authors: Roushan Mohammad Reza Hasanjani , Ebrahimpour Soheil , Afshar Zeinab Mohseni , Babazadeh Arefeh 
Published: August 2019

Abstract

Introduction
Human brucellosis, the most prevalent zoonotic disease worldwide, is a systemic infection which can involve several organs. Among musculoskeletal complaints, spondylitis is the most frequent complication of brucellosis and primarily affects the lumbar and thoracic vertebrae. The involvement of the cervical spine is infrequent.

Case report
This case report concerns an unusual case of cervical spine spondylitis with an epidural abscess due to Brucella in a 43-year-old man. The diagnosis was based on the patient being domiciled in an endemic region, his symptoms and his occupation. Clinical outcomes improved following antimicrobial therapy of rifampin, doxycycline, and gentamycin, and were confirmed radiologically.

Conclusion
Early diagnosis and treatment are crucial for these patients. The timely commencement of medical treatment can help prevent surgery.
The Management of a Thirteen Weeks Pregnant Woman Rendered Brain-Dead Following a Ruptured Aneurysm
Authors: Pikto-Pietkiewicz Iwona , Okniński Antoni , Wójtowicz Rafał , Wójtowicz Marlena 
Published: August 2019

Abstract

Introduction
The current lack of clear guidelines on how to manage cases of brain-dead pregnant patients makes this topic controversial and extremely difficult to deal with for both medical and ethical reasons. This report deals with such a situation.

Case presentation
A twenty-seven years old woman, thirteen weeks pregnant, with a ruptured brain aneurysm was admitted to an Intensive Care Unit. She presented with loss of all brain functions, but somatic support was sustained to enable the delivery of her baby.

Conclusion
The case report gives a detailed account of the management of the mother before the successful delivery of her baby. It indicates the need for ongoing contributions to the debate on this delicate subject area to establish guidelines on how to manage brain-dead pregnant patients.
Precision Medicine and its Role in the Treatment of Sepsis: A Personalised View
Authors: Lazăr Alexandra , Georgescu Anca Meda , Vitin Alexander , Azamfirei Leonard 
Published: August 2019

Abstract
In recent years, a new form of medicine has become increasingly significant, namely, personalised medicine (PM). PM is a form of care in which treatment is tailored for an individual patient.
PM is about using multiple data sets to create a digital human mapping. A person’s biological traits are determined by the interactions of hundreds of genes and gene networks, as well as external factors such as diet and exercise. Combining and then investigating these multiple databases with powerful statistical tools, allows a new understanding of how genetic intricacy drives health and disease and so leads to a closer personalised medical approach that targets each individual’s unique genetic make-up.
Sepsis is a systemic inflammatory response to infection, ranging from systemic inflammatory response syndrome (SIRS) to septic shock and multiple organ dysfunction syndromes (MODS). Sepsis is the most common cause of death in intensive care patients. Treatments in an ICU may need to be adapted to the continuous and rapid changes of the disease, making it challenging to identify a single target. PM is thus seen as the future of sepsis treatment in the ICU.
The fact that individual patients respond differently to treatment should be regarded as a starting point in the approach to providing treatment. The disease itself comes secondary to this concept.