bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of two levels of partial neuromuscular block with atracurium on the ventilatory response to hypercapnia in anesthetized Beagles
Authors: Sakai Daniel M. , Martin-Flores Manuel 
Published: August 2018

Abstract
OBJECTIVE To evaluate effects of 2 levels of partial neuromuscular block on the ventilatory response to a hypercapnic challenge in anesthetized dogs and to evaluate effects of edrophonium for reversing partial neuromuscular block.
ANIMALS 6 healthy adult Beagles.
PROCEDURES Each dog was anesthetized twice with propofol and dexmedetomidine. End-tidal partial pressure of CO2 (Petco2), tidal volume (Vt), and peak inspiratory flow (PIF) were measured during breathing at rest. Maximal Vt and PIF (VtMAX and PIFMAX, respectively) in response to a hypercapnic challenge consisting of 10% CO2 inhaled for 1 minute were measured. Variables were measured before administration of atracurium (baseline), during moderate (train-of-four [TOF] ratio, 0.3 to 0.5) and mild (TOF ratio, 0.6 to 0.8) atracurium-induced neuromuscular block, and after neuromuscular block recovery (TOF ratio, ≥ 0.9) following administration of edrophonium or saline (0.9% NaCl) solution. Dogs for which any variable returned to < 80% of the baseline value were identified.
RESULTS Partial neuromuscular block increased Petco2; it impaired Vt at rest and VtMAX but not PIF at rest and PIFMAX. All variables except Petco2 returned to baseline values when the TOF returned to ≥ 0.9. After recovery from neuromuscular block, significantly more dogs had a VtMAX < 80% of the baseline value when edrophonium was not administered.
CONCLUSIONS AND CLINICAL RELEVANCE Partial neuromuscular block in anesthetized Beagles decreased spontaneous ventilation at rest and impaired the response to a hypercapnic challenge. Response to hypercapnic challenge might remain partially impaired after recovery of the TOF ratio to ≥ 0.9.
Assessment of pig saliva as a Streptococcus suis reservoir and potential source of infection on farms by use of a novel quantitative polymerase chain reaction assay
Authors: Arai Sakura , Kim Hyunjung , Watanabe Takayasu , Tohya Mari , Suzuki Eriko , Ishida-Kuroki Kasumi , Maruyama Fumito , Murase Kazunori , Nakagawa Ichiro , Sekizaki Tsutomu 
Published: August 2018

Abstract
OBJECTIVE To evaluate colonization of Streptococcus suis and Streptococcus parasuis on pig farms in Japan and to identify sources of infections.
SAMPLE Saliva, feces, and vaginal swab samples from 84 healthy pigs of several growth stages on 4 farms and swab samples of feed troughs and water dispensers at those farms.
PROCEDURES Samples were collected from August 2015 to June 2016. Two quantitative PCR (qPCR) assays (one for S suis and the other for S parasuis) were designed for use in the study. The novel qPCR assays were used in combination with previously described qPCR assays for S suis serotype 2 or 1/2 and total bacteria. Relative abundance of bacteria in each sample was evaluated.
RESULTS Streptococcus suis was detected in all saliva samples and some of the other samples, whereas S parasuis was not detected in any of the samples, including saliva samples, which indicated a difference in colonization preference. The ratio of S suis to total bacteria in saliva appeared to increase with age of pigs. Streptococcus suis serotype 2 or 1/2 was detected in a few saliva samples and feed trough swab samples at 2 farms where S suis infections were prevalent.
CONCLUSIONS AND CLINICAL RELEVANCE Saliva, especially that of sows, appeared to be a reservoir and source of S suis infection for pigs. The qPCR assay described here may provide an effective way to monitor for S suis in live pigs, which could lead to effective disease control on pig farms.
Retention of gadolinium in the brains of healthy dogs after a single intravenous administration of gadodiamide
Authors: Gambino Jennifer M. , James Judy R. , Buchweitz John P. , Cooley A. Jim , Lawrence Amanda M. , Wills Robert W. , Lee Alison M. 
Published: August 2018

Abstract
OBJECTIVE To determine brain region affinity for and retention of gadolinium in dogs after administration of gadodiamide and whether formalin fixation affects quantification.
ANIMALS 14 healthy dogs.
PROCEDURES 13 dogs received gadodiamide (range, 0.006 to 0.1 mmol/kg, IV); 1 control dog received a placebo. Dogs received gadodiamide 3 to 7 days (n = 8) or 9 hours (5) before euthanasia and sample collection. Brain regions were analyzed with inductively coupled mass spectrometry (ICP-MS) and transmission electron microscopy. Associations between dose, time to euthanasia, and gadolinium retention quantities (before and after fixation in 5 dogs) were evaluated.
RESULTS Gadolinium retention was seen in all brain regions at all doses, except for the control dog. Exposure 3 to 7 days before euthanasia resulted in 1.7 to 162.5 ng of gadolinium/g of brain tissue (dose-dependent effect), with cerebellum, parietal lobe, and brainstem affinity. Exposure 9 hours before euthanasia resulted in 67.3 to 1,216.4 ng of gadolinium/g of brain tissue without dose dependency. Transmission electron microscopy revealed gadolinium in examined tissues. Fixation did not affect quantification in samples immersed for up to 69 days.
CONCLUSIONS AND CLINICAL RELEVANCE Gadodiamide exposure resulted in gadolinium retention in the brain of healthy dogs. Cerebellum, parietal lobe, and brainstem affinity was detected with dose dependency only in dogs exposed 3 to 7 days before euthanasia. Fixation had no effect on quantification when tissues were immersed for up to 69 days. Physiologic mechanisms for gadolinium retention remained unclear. The importance of gadolinium retention requires further investigation.
Endotoxin-induced changes of type VII collagen– cleaving matrix metalloproteinases in lamellar tissue of extracorporeally perfused equine limbs
Authors: Patan-Zugaj Bianca , Gauff Felicia C. , Egerbacher Monika , Licka Theresia F. 
Published: August 2018

Abstract
OBJECTIVE To investigate the effect of lipopolysaccharide (LPS) on type VII collagen– cleaving matrix metalloproteinases (MMPs) in the lamellar tissue of extracorporeally perfused equine limbs.
SAMPLE 10 right forelimbs and 3 left forelimbs collected from 10 adult horses after slaughter at a licensed abattoir.
PROCEDURES Extracorporeal perfusion of the isolated equine limbs was performed for 10 hours under physiologic conditions (control-perfused limbs; n = 5) and with the addition of 80 ng of LPS/L of perfusate (LPS-perfused limbs; 5). Lamellar tissue specimens were then collected from the dorsal aspect of the hooves. Additionally, corresponding control specimens were collected from the 3 nonperfused left forelimbs. Immunohistochemical analysis was performed on paraffin-embedded tissue blocks with antibodies against total (latent and active) MMP-1, MMP-2, MMP-8, and MMP-9 as well as antibody against active MMP-9. Intensity of immunohistochemical staining was scored, and stain distribution in the lamellar tissue was noted.
RESULTS Staining intensity of total and active MMP-9 was significantly increased in LPS-perfused versus control-perfused limbs. No such difference was identified for MMP-1, MMP-2, and MMP-8.
CONCLUSIONS AND CLINICAL RELEVANCE Of the 4 MMPs that are capable of degrading type VII collagen, MMP-9 was the only one for which production increased in the lamellar tissue of isolated equine limbs perfused with versus without a clinically relevant concentration of LPS. These results suggested that MMP-9 may be involved in initiation of pathological changes in lamellar tissue in endotoxin-induced laminitis, whereas MMP-1, MMP-2, and MMP-8 may be less relevant.
La nueva visión del territorio mesoamericano y de las ruinas mayas a través de los dibujos del artista inglés Frederick Catherwood
Authors: Blasco Dragun Estefanía Sol 
Published: August 2018

El presente trabajo se propone indagar acerca de la construcción de una nueva visión sobre Mesoamérica a partir de las imágenes producidas por el artista ingles Frederick Catherwood durante su viaje por las tierras centroamericanas a mediados del siglo XIX, en compañía de John Lloyd Stephens. A través del recorrido por la biografía del artista, recuperando la importancia de los viajes y sus relatos desde los primeros contactos entre Europa y América, y revisando el viaje realizado por estos dos personajes, nos centraremos en el análisis de las imágenes publicadas en 1844 bajo el titulo Views of Ancient Monuments in Central América, Chiapas and Yucatán. Con este trabajo buscamos recuperar la importancia de este artista en la historia de los contactos entre Europa y América y en la posterior exploración de los territorios americanos a partir de nuevos paradigmas que otorgaron mayor valor a la antigüedad americana.
Traducciones para y por los españoles americanos
Authors: González Núñez Gabriel 
Published: August 2018

Consabido es que la emancipación política del continente americano supuso un proceso largo y violento en que las colonias se fueron desprendiendo de sus respectivas metrópolis. Los distintos revolucionarios, patriotas y libertadores actuaron en su contexto colonial inmediato, y sin embargo, existió a lo largo de toda América un caudal de ideas compartidas que sirvieron, sobre todo, para justificar dichas acciones. Estas ideas, surgidas en gran medida de la Ilustración europea y puestas en práctica en América inicialmente en las ex colonias inglesas, se diseminaron, en parte, a lo largo de todo el dominio hispanoamericano mediante la traducción. Se trató de hombres que viajaron a diversos destinos por motivos varios y allí absorbieron las ideas y la práctica del naciente republicanismo democrático, con toda su promesa e imperfecciones. Ansiosos de hacer circular estos conceptos y ejemplos, se unieron al espíritu revolucionario con la pluma, traduciendo cartas, libros, constituciones, etc. Estos traductores jugaron, de ese modo, el papel de diseminar ideas con el objetivo de definir nuevos parámetros políticos y culturales en sus sociedades de origen. Este trabajo pretende explorar la función que en colectivo desarrolló la traducción durante la emancipación de Hispanoamérica.
Usos de la noción de “pueblo” en Tucumán en tiempos de las invasiones inglesas
Authors: Lupiañez Gabriela 
Published: August 2018

Este escrito se propone comprender el modo en que algunos agentes de la elite del pueblo de Tucumán (cabildo y notables), pertenecienteal virreinato del Río de la Plata, entendieron y practicaron la relación con las autoridades superiores con sede en Buenos Aires y peninsulares entre mediados de 1806 y mediados 1808. Un tiempo de “autonomía de hecho” – en el que quienes debían obedecer comenzaron a tomar decisiones sobre el gobierno impensables con anterioridad- que fue efecto imprevisto de las invasiones británicas a los dominios más australes de la monarquía hispana. Con ese objeto, se propone indagar sobre los usos (sentidos) de la noción de “pueblo”. Ésta noción remitía tradicionalmente a un sujeto central en la estructura de la monarquía hispana en América. Sin embargo, pronto debió lidiar con nuevos sentidos. Se propone que los pueblos tuvieron un rol importante en la defensa de Buenos Aires así como mantuvieron una relación de reciprocidad con el rey.
Enantioselective Multi-Component Cyclopropane Synthesis Enabled by Cu-Catalyzed Cyclopropene Carbometallation with Organoboron Reagent
Authors: Li Zhanyu , Zhang Mengru , Zhang Yu , Liu Shuang , Zhao Jinbo , Zhang Qian 
Published: August 2018

Deployment of organoboron in lieu of the strongly basic organometallic reagents as carbon source in Cu-catalyzed cyclopropene carbometallation opens unprecedented three-component reactivity for stereoselective synthesis of poly-substituted cyclopropanes. A proof-of-principle demonstration of this novel carbometallation strategy is presented herein for a highly convergent access to poly-substituted aminocyclopropane framework via carboamination. Preliminary results on asymmetric desymmetrization with commercial bisphosphine ligands attained high levels of enantioselection, offering a straightforward access to enantioenriched aminocyclopropanes bearing all-three chiral centers, including an all-carbon quaternary center. This strategy may underpin a host of novel synthetic protocols for poly-substituted cyclopropanes.
A DIGNIDADE DA PESSOA HUMANA NA VISÃO DE INGO W. SARLET: DESDE A PROBLEMATIZAÇÃO DO CONCEITO ATÉ O PENSAR FORA DO MARCO JURÍDICO ESTABELECIDO
Authors: Esteves Alan da Silva , Molinaro Carlos Alberto 
Published: August 2018

O conceito de dignidade da pessoa humana formulado pelo jurista Ingo W. Sarlet é problematizado. A tese acolhida é a de que o direito se interessou pelo conceito para formatar o futuro e trabalhar as possibilidades do presente. Isso identificou a necessidade de que o conceito deva atender, além do marco tradicional – ligação com os direitos e deveres fundamentais –, a um itinerário de que seja a voz que aumenta a capacidade de indignação quando o homem é confrontado com a violação dos direitos humanos e fundamentais, com a injustiça e com as opressões.
Pembayangan Mandiri pada Material Bata Ringan di Iklim Tropis
Authors: Hilmy Mochamad , Indriana Dewi Ria 
Published: August 2018

The purpose of this study was to obtained recommendations on the use of innovative building materials from the development of existing lightweight concrete designs, to decrease the building interior temperature. The research used an engineering experimental method on lightweight concrete as material tested. A profile was attached on the outer side of lightweight concrete in order to formed a shadowed effect and expected to make the building indoor temperature go lower. The result indicated that the shadows shaped by profile attached on the outer side of lightweight concrete not fully effectively in decreasing building indoor temperature. The lightweight concrete thickness affected the velocity of solar thermal radiation impact movement that goes into the buildings interior. The formation of profiles on lightweight concrete surfaces can be decrease the room temperature in at least more than 2°C. The shading was more effective if the profile form in vertical formation. The research output was a lightweight concrete prototype that was able to contribute to decrease the building indoor temperature.
Pengaruh public relation dan strategi periklanan terhadap keputusan pembelian produk samsung galaxy
Authors: Sari Desi Novita , Noorlitaria Gusti , Asnawati Asnawati 
Published: August 2018

AbstractThis study aimed to find out : (1) influence of public relation to purchasing decision at Politeknik Negeri Samarinda students, (2) influence of advertising strategy to purchasing decision at Politeknik Negeri Samarinda students, (3) influence of public relation and advertising strategy to purchasing decision at Politeknik Negeri Samarinda Students. This research is a survey research. The population of this research is Politeknik Negeri Samarinda students using Samsung Galaxy mobile phone product. The sampling method used in this research is accidental sampling with 120 respondents. The collected questionnaire data has been tested using validity and reliability. The data analysis technique of this research is multiple linear regression.The results showed that : (1) the public relation positively effected purchasing decisions with a significance value of t-test is smaller than the specified level of significance (2) the advertising strategy positively effected purchasing decisions with significant value t-test is smaller than the specified level of significance (3) the public relation and advertising stategy together positively effected purchasing decisions with significant value f-test is smaller than the specified level of significance. Keywords : Public Relation, Advertising Strategy, Purchase Decision.
Variabel yang mempengaruhi motivasi dan kinerja pegawai pada kantor perpustakaan dan arsip daerah di kabupaten paser
Authors: Idhamsyah Idhamsyah , Ilmi Zainal , Lestari AS Dirga 
Published: August 2018

Human Resource Management is a resource of Development to emphasize human being as the main actors of development having work ethic or working method that productive, creative, discipline, skilled, professional and master of science and technology with environment or natural surroundings, ability to manage and also interact with all forms of work. Organizations need a good performance of every human resource they have in order to better the community's assessment of the organization as well, so the organization also needs to take various actions in achieving the good performance generated by its employes. The purpose of this study is to analyze and determine the influence of Variables Affecting Employee Motivation and Performance. This research was conducted by taking the object of the Office of Library and Archives Region Office in Paser Regency, with a population of 40 employees. The theory used is the theory of human resource management, Competence, Experience, This study uses data taken directly from the sample by using a questionnaire system. The samples of the research are the employees of the Library and Archive Regional Office in Paser Regency with a total of 40 samples. The research model uses path analysis using SmartPLS as an analytical tool. From the result of the analysis test, it can be concluded that the competence variable (X1) has a significant and positive effect on the motivation (Y1), and on the performance (Y2), the experiential variable (X2) has a significant positive effect both on motivation (Y1) and performance (Y2) Compensation variable (X3) has a significant and positive effect on Motivation (Y1), and on Performance (Y2), and. And Motivation variable (Y1) have a significant effect on performance variable (Y2). Keywords: Performance, Motivation, Compensation, Competence
Speedup-Oriented History-Based Tiling Algorithm for the HEVC Standard Targeting an Efficient Parallelism Exploration
Authors: Storch Iago , Palomino Daniel , Zatt Bruno , Agostini Luciano 
Published: August 2018

This paper proposes a history-based tiling algo-rithm intending to increase the speedup when using Tiles. The algorithm is composed of two independent steps that use work-load history information to define the vertical and horizontal boundaries of the Tiles. The workload distribution of previous frames is used as reference to perform the tiling of the current frame, exploiting the temporal similarity between neighboring frames, focusing on improving the speedup. Experimental re-sults show that the proposed algorithm outperforms the speedup when compared to uniform tiling by up to 38%, whereas posing no significant complexity increase nor coding efficiency losses. When compared to related works the proposed solution also presents better results.
A Temperature-Aware Analysis of SAR ADCs for Smart Vehicle Applications
Authors: V. Fonseca Adriano , Maris Ferreira Pietro , Cron Ludwig , Barúqui Fernando A. P. , Soares Carlos F. T. , Benabes Philippe 
Published: August 2018

The challenges of the Internet of Things (IoT) in an urban environment are driven by smart vehicles which need to be able to efficiently sense and communicate with other nearby vehicles. The automotive market have strict circuit performances and reliability requirements for a temperature range of up to 175 ◦C. This proposal overviews an analysis of latched-comparators performance, considering process variability and temperature variation of previous works. This analysis is then extended to the metastability and performance metrics of successive approximation register (SAR) analog-to-digital converter (ADC) topology. Building blocks necessary for the SAR ADC are designed using an XH018 technology. Post-layout simulation results are drawn to validate the proposed temperature-aware analysis. Besides the known advantages of the Double-Tail comparator, this work demonstrates that such a comparator has a serious drawback under harsh environments. This proposal also shows that, once calibrated and operated at a frequency of around 100 MHz, the SAR ADC performance can be maintained in a wide temperature range. Both SA- and DT-SAR ADC achieve an ENOB of 9.8 bits, which is reduced to 9.6 bits in high-temperature operation. The results also show that background calibration is not required for the SAR ADC operation at the 100 MHz frequency range.
‘There is no better means of instruction on China than letting China speak for herself’: Thomas Percy and Hau Kiou Choaan
Authors: Yan Mengmeng , Yan Mengmeng 
Published: August 2018

Hau Kiou Choaan represents a fresh enquiry into literary orientalism in Britain of the eighteenth century. This article will discuss Percy's adaptation of Hau Kiou Choaan from an original Chinese novel, and how the ways in which Percy interprets the Chinese novel signify his peculiar views of China. On the title page of Hau Kiou Choaan; or, The Pleasing History (1761), Thomas Percy quotes from Jean-Baptiste Du Halde’s A Description of the Empire of China and of Chinese Tartary (1738): ‘There is no better means of instruction on China than letting China speak for herself’. It remains questionable, whether by presenting an original piece of Chinese literature, Percy has really let China ‘speak for herself’; it is reasonable to argue that Hau Kiou Choaan carries as much information about China as it does about Percy’s own perceptions of this country. Whether Percy’s works and views of China provoked louder criticism or higher praise, his input into the studies of China was a positive one, for it contributed to an increasingly vigorous debate that would increasingly perceive differences as a source of strength, not weakness.
Introduction: Play, Visual strategies and Innovative Approaches to Graduate Student Writing Development
Authors: Amell Brittany , Badenhorst Cecile 
Published: August 2018

We begin by introducing the special section of the Canadian Journal for Studies in Discourse and Writing/Rédactologie on play, visual strategies and innovative approaches to graduate student writing development. Most exciting for us to see as editors of this special section is how many authors from various locales are drawing on creative methods, signalling to us that in some ways this is a burgeoning area. We have papers from Germany, the U.K., Thailand, and at least three provinces in Canada. We have some poetry, examples of collages, photos of cats, shapes, and Lego™. We include the abstracts for each of the papers.
A case of autoimmune polyglandular syndrome type 1 with ectodermal dystrophy in her nail
Authors: Genç Merve , Gültekin Korcan , Önal Ayşe , Güngüneş Aşkın , Arıkan Durmaz Şenay 
Published: August 2018

Autoimmune
polyglandular syndrome type 1 (APS-1), also called autoimmune polyendocrinopathy-candidiasis-ectodermal
dystrophy, has three major components including mucocutaneous candidiasis,
hypoparatiroidism and Addison’s disease. It is an autosomal recessive disorder.
Mutations in the AIRE gene found on chromosome 21 are the cause of this disease.
A 21-year-old female patient with Addison's disease was admitted to our
outpatient clinic for routine control. The patient was diagnosed
with Addison's disease at the age of six when she applied for a complaint of
fatigue and hyperpigmentation. She was diagnosed with primary
hypoparathyroidism after 6 months. Physical examination revealed that mucocutaneous candidiasis at her
mouth and ectodermal
dystrophy at her right hand second
finger’s nail. The patient had no hair on the pubic or
axillary region. Asplenism was detected in the abdominal
ultrasound examination. In
conclusion, patients with APS-1 can be presented with ectodermal dystrophy and it must be paid
attention to ectodermal dystrophy during diagnostic evaluation.