bluuebunny/crossref_metadata_2025_split huggingface dataset:
Probabilistic Robust Damping Controller Optimization for Mitigating Subsynchronous Control Interaction in DFIG and PMSG‐Based Wind Farms
Authors: Bodapatla Sampath Kumar , Ghodake Sagar M. , Kadam Prakash D. , Bansode Rupali 
Published: December 2024

ABSTRACTAdvanced control and mitigation solutions are required due to the enormous challenges posed by sub‐synchronous control interaction in wind farms. These concerns include system instability, potential damage to turbines, and grid stability issues. This research presents the probabilistic robust damping controller, an adaptive control approach, to address the issues in grid‐connected wind farms. The innovation employs the balanced remora optimization algorithm to optimize controller parameters, ensuring system stability under various conditions. For permanent magnet synchronous generator‐based wind farms with weak grid circumstances, critical elements such as the DC‐link voltage, the d‐q axis current reference, and the actual values in the grid‐side converter are essential for problem mitigation. The controller generates controlled output using these input signals. The MATLAB‐based implementation demonstrates the controller effectiveness in damping issues within a series‐compensated doubly fed induction generator. Comparative analysis with conventional controllers under different grid conditions and disturbances validates its superior performance. Time‐domain simulations, both with and without time delay, further confirm the controller's ability to enhance system stability and dampen the issues. Four schemes are used to evaluate the doubly fed induction generator‐based wind farms: wind speed at 13 m/s with 75% series compensation, 7 m/s with 75% compensation, 9 m/s with 45% compensation, and 9 m/s with 60% compensation. Under short circuit ratio, the wind farms based on permanent magnet synchronous generators are analyzed in three scenarios: normal, strong, and weak cases.
A Pilot Study of a Novel Dietary Intervention Targeting Ultra‐Processed Food Intake
Authors: Hagerman Charlotte J. , Hong Asher E. , Jennings Emma , Butryn Meghan L. 
Published: December 2024

ABSTRACTBackgroundUltra‐processed foods (UPFs) are harmful to health but ubiquitous in the modern food environment, comprising almost 60% of the average American diet. This study assessed the feasibility, acceptability, and preliminary efficacy of a novel behavioral intervention designed to reduce UPF intake.MethodsFourteen adults participated in an 8‐week pilot intervention, which consisted of weekly group sessions, individual meal planning sessions, and financial support. Dietary intake was assessed using three Automated Self‐Administered 24‐h Dietary Recalls (ASA24) at both baseline and post‐treatment.ResultsThe intervention was highly feasible and acceptable. Qualitative data demonstrated that participants were enthusiastic about the benefits of reducing UPF intake and found the intervention highly valuable. Participants reduced average daily calories from UPF by 48.9%, number of UPFs consumed by almost half, total daily calorie intake by 612 calories/day, sodium consumption by 37% and sugar consumption by 50%. There were no significant changes in fruit or vegetable intake. Participants lost an average of 3.5 kg (SD = 3.0 kg).ConclusionThis pilot data suggests that behavioral interventions to reduce UPF intake will be well‐received and are capable of success despite the barriers of the United States food environment. Future research should prioritize behavioral interventions targeting UPF consumption alongside policy changes.
High Performance Antibacterial Structure‐Tuned Hemofiltration Membrane for Facile Permeability of Blood Plasma During Plasmapheresis
Authors: Dehghan Rahim , Barzin Jalal , Kordkatooli Zahra 
Published: December 2024

ABSTRACTA microfiltration membrane is designed to separate blood cells without altering plasma composition. A vapor‐induced phase separation (VIPS) combined with compositional adjustment is used to create a structure‐tuned hemofiltration membrane. Polyvinylpyrrolidone (PVP‐K90), polyethylene glycol (PEG400), and either water or chlorohexidine gluconate (CHG) solution are employed to regulate membrane structure and provide antibacterial enhancement. The preparation conditions involve a 5‐min VIPS process at moderate temperature and high humidity to craft the desired membrane structure. Morphological studies show that the membranes have an asymmetric sponge‐like structure with controlled surface pore sizes that effectively separate blood cells while enabling plasma passage. Complete blood count (CBC) analysis reveals that MH2 and MH3 membranes exhibit significant potential for blood cell separation, with 78% platelet (PLT) separation, 80% red blood cell (RBC) separation, and over 90% white blood cell (WBC) separation. Biochemical analysis of plasma substances confirms that components such as fasting blood sugar (FBS), blood urea nitrogen (BUN), creatinine, albumin, high‐density lipoprotein, and low‐density lipoproteins pass through the MH series without significant concentration changes. The outcomes suggest that the MH series offers high blood compatibility as evidenced by coagulation times and hemolysis ratio. In addition, MTT data validates the biocompatibility of the membrane. Biofilm inhibition results and biofouling study confirmed that MH series, especially MH2 and MH3 exhibit superior characteristics and performance for plasmapheresis applications.
Social transfers and poverty alleviation in Taiwan from 2000 to 2020
Authors: Chen Ke‐Mei , Shih Yao‐Chi , Hung Hui‐Fen , Wang Ching‐Yi , Cheng Ching‐Hsia 
Published: December 2024

AbstractThis study explored the effectiveness of government social transfers in alleviating poverty and investigated the profile and reduction of income poverty in Taiwan before and after these transfers by using the Foster–Greer–Thorbecke (FGT) class of poverty measures. Data were obtained from the 2000–2020 Survey of Family Income and Expenditure. Significant progress was made in reducing poverty over the study period. The three FGT poverty measures before and after transfers peaked in 2009 and 2010, respectively, during the global financial crisis. The findings also suggested that poverty varied considerably across the subgroups. Poverty was more prevalent in female‐headed and older adult‐headed households than in male‐headed and younger adult‐headed households before and after transfers. However, the degree of poverty reduction was greater in female‐headed and older adult–headed households, and these households made greater contributions to overall poverty over time. In addition, heterogeneity was identified among the household types, and grandparent, couple, and single‐person households were identified as the most disadvantaged groups. The high number of means‐tested programs suggests piecemeal welfare benefits in Taiwan. The people living in poverty in our study relied considerably on various social transfers. Accordingly, integrated and universal welfare programs should become a key focus of policy.
Computational Insight in the Identification of Non‐Synonymous Single‐Nucleotide Polymorphism Affecting the Structure and Function of Interleukin‐4
Authors: Roy Pratima , Sharma Siddharth , Baranwal Manoj 
Published: December 2024

ABSTRACTBackgroundIL4 is a versatile cytokine essentially known for differentiation, proliferation and cell death in cells. Its dysregulation has been found to be associated with the development of inflammatory disorders.ObjectiveThe goal of the current investigation is to identify and select non‐synonymous single‐nucleotide polymorphisms (nsSNPs) in the IL‐4 gene by employing computational methods which may have a potential functional impact on the occurrence of disease.Method and ResultSix different nsSNPs were predicted to be deleterious based on the consensus of different algorithms: SIFT, Polyphen2 (Humdiv and HumVar), PredictSNP and SNP&GO. I‐mutant and MuPro assessment revealed a decrease in the stability of these mutants except K150M. Modelling was then carried out to build the wild type along with its mutants, followed by superimposition of the wild type with mutants to evaluate the RMSD value, which lies between 0.26 and 0.34. Simulation results of mutant models, along with wild type, showed that four of the mutants (N113Y, A118G, R109W and K150M) deviated most and were unstable. A118G showed a significant deviation from the wild type, while V53A and C123R were stable.ConclusionThe finding establishes the evidence that the identified six nsSNPs of IL‐4 can be the new entrant presenting their candidature for genetic testing.
Transgenic expression of SeCYP9A186 and PxFMO2 confers resistance to emamectin benzoate in Plutella xylostella
Authors: Wang Falong , Chen Shiqi , Shi Yu , Wu Shuwen , Yang Yihua , Wang Xingliang 
Published: December 2024

AbstractBACKGROUNDThe overexpression of metabolic enzymes constitutes a crucial mechanism for insects to detoxify xenobiotics and metabolic pesticides. A flavin‐containing monooxygenase gene (PxFMO2) from Plutella xylostella and a P450 gene (SeCYP9A186, F116V mutant allele) from Spodoptera exigua have been reported to be involved in insecticide resistance. In this study, we aim to utilize transgenic technology to validate their in vivo detoxification functions in Plutella xylostella.RESULTSWe established two transgenic strains of Plutella xylostella with expressing an endogenous PxFMO2 gene from Plutella xylostella and an exogenous SeCYP9A186 gene from S. exigua, respectively. Bioassays demonstrated that the transgenic Plutella xylostella strain (IPP‐FMO2) expressing PxFMO2 exhibited a 12‐fold resistance to emamectin benzoate and a 6.4‐fold resistance to chlorantraniliprole compared to the background strain (IPP‐S). In contrast, the transgenic Plutella xylostella strain (IPP‐9A186) expressing SeCYP9A186 displayed a 235‐fold resistance to emamectin benzoate and a 115‐fold resistance to abamectin. Moreover, resistance to emamectin benzoate in the IPP‐9A186 strain of Plutella xylostella was inherited as an incompletely dominant trait and was genetically linked to the transgene locus.CONCLUSIONSOur results not only elucidated the in vivo contribution of the PxFMO2 and SeCYP9A186 to the insecticide resistance phenotype in Plutella xylostella, but also provided a genetic engineering toolkit to manipulate resistance pathways. These insights and methodologies could further aid in developing sustainable pest management strategies in Plutella xylostella. © 2024 Society of Chemical Industry.
Endoscopic ultrasound with bronchoscope‐guided transesophageal cryobiopsy: A case series with technical insights, key enablers, and review of literature
Authors: Soo Chun Ian , Leong Wai Ling , Ong Diana Bee‐Lan , Looi Lai‐Meng , Sia Leng Cheng , Munusamy Vijayan , Wong Chee Kuan , Huan Nai‐Chien , Ramarmuty Hema Yamini , Ng Khai Lip , Ng Boon Hau , Khairul Annuar Hazwan Amzar , Kho Sze Shyang 
Published: December 2024

AbstractEndobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) is an established technique for lung cancer staging and the diagnosis of mediastinal diseases. Recently, the paradigm of EBUS guided mediastinal sampling with conventional cytology has shifted over to histology specimens through the use of cryobiopsy. This case series explores the novel technique, key enablers, and potential advantages of endoscopic ultrasound with bronchoscope‐guided transesophageal cryobiopsy (EUS‐B‐TEC). The findings of this case series suggest that EUS‐B‐TEC is a safe and valuable addition to the bronchoscopic procedural armamentarium. Further studies are warranted to validate the potential of EUS‐B‐TEC.
Small cell lung cancer presenting with pleural effusion and superior vena cava obstruction
Authors: Khan Allahdad , Batool Arshia , Ain Qura‐tul , Hashmi Ali Haider , Islam Muhammad , Kamal Aseel 
Published: December 2024

Key messageSmall cell lung cancer with concurrent pleural effusion and superior vena cava obstruction is a rare presentation with high risk of respiratory and circulatory compromise warranting prompt and multidisciplinary treatment.
A rare case of oropharyngeal metastasis from lung adenocarcinoma
Authors: Morimoto Toshiki , Yamasaki Kei , Kawamura Yuki , Meguro Maika , Nagasawa Taiga , Fujimoto Satoshi , Hiraga Saki , Tahara Masahiro , Yatera Kazuhiro 
Published: December 2024

Key messageOropharyngeal metastasis from other organs is rare, especially from lung cancer. However, in lung cancer cases, the oropharynx should be considered a potential site for distant spread.
Multiloculated pyopneumothorax with subcutaneous emphysema and pneumomediastinum in a tuberculosis patient
Authors: Ain Qura Tul , Khan Allahdad , Batool Arshia , Habib Mudasira , Islam Muhammad , Antar Mohamed 
Published: December 2024

Key messagePulmonary tuberculosis with the simultaneous development of the complications of empyema, multiloculated pyopneumothorax, subcutaneous emphysema and pneumomediastinum is rare. The development of these complications leads to remarkably increased incidence of morbidity and mortality in patients. So appropriate and timely management needs to be ensured for better outcomes.
Manipulator Trajectory Planning Based on Clustering Curve Discretization and B‐Spline
Authors: Peng Yanhua , Tang Biao , Huang Delong , Wei Yikang 
Published: December 2024

ABSTRACTIn addressing the welding trajectory planning problem for a six‐axis robot under visual guidance, a method based on clustering and isometric image trajectory curve discretization is proposed to enhance welding trajectory precision and improve welding quality. Firstly, the kinematic model of the six‐axis robot is established using the D‐H parameter method. Subsequently, the discrete processing of the welding trajectory map recognized by an industrial camera and chord error calculation are performed. The discrete trajectory is then interpolated using fifth‐order non‐uniform B‐spline interpolation, with welding speed planning based on an S‐shaped speed planner. Finally, the planned trajectory is verified by welding simulation in MATLAB and V‐REP simulation. The simulation results show that the end trajectory of the manipulator is smooth and stable. Compared with the equal arc length discretization method, the discretization accuracy of the proposed method is improved by 19% (plane curve) and 10.7% (space curve), indicating that the proposed discretization method improves the end tracking accuracy of the six‐axis robot.
Interactions Among Text Formats and Reading Processes in Young Learners' L1 Reading Literacy
Authors: Hódi Ágnes , Tóth Edit , Nikolov Marianne 
Published: December 2024

AbstractReading literacy is a multidimensional construct in terms of text and reading processes. Much research has examined the divisibility of the processes underlying reading, but they have treated the rest of the construct as unitary. This study extends the examination of dimensionality to a neglected area in literacy studies. It tests reading models by integrating text formats (continuous, mixed, and non‐continuous) and cognitive processes involved in reading (information retrieval, interpretation, and reflection) and their interaction in a large dataset. The study aims to complement the results of previous research by analyzing how cognitive aspects function in the meaning‐making process in various text formats. Representative samples (N = 3229) of young Hungarian L1 learners participated in the study. Data obtained from a longitudinal study in grade 2 and grade 4 is used to test the underlying measurement model of reading literacy and to explore the issue of the dimensionality of reading processes along three different text formats. Findings suggest that students' reading development trajectory and rate differs when it comes to reading texts with different formats. Text formats affect reading subskills significantly but the interaction between text and reading processes changes over time. Results provide a clearer understanding of the text format achievement gap. Implications for research and practice are discussed.
Learning to Read and Developmental Dyslexia in Hebrew
Authors: Shechter Adi , Share David L. 
Published: December 2024

AbstractThe study of Hebrew, a non‐European language written in a non‐alphabetic (abjadic) script offers valuable insights into the science of reading beyond the well‐studied alphabetic scripts. Because reading development in Hebrew is shaped by the uniquely Semitic root‐and‐pattern morphology and the abjadic (predominantly consonantal) orthography, our review begins by providing some basic information about the Hebrew language and its writing system. We then outline the developmental phases through which the developing Hebrew reader progresses, as proposed in Share and Bar‐On's Triplex Model, and the central role of phonological and morphological awareness. Finally, we review the research literature on developmental dyslexia in Hebrew within the context of current theories on the underlying perceptual/neurobiological basis of dyslexia (e.g., temporal processing, magnocellular deficits, visual attention span etc.). Here, we draw attention to the problems of comorbidity and the need to go beyond the conventional “whole‐group” approach and address the issue of heterogeneity and subtypes.
Is Sustainable Innovation an Impetus to Sustainable Development Goals? Evidence From the EU
Authors: Khan Khalid , Khurshid Adnan , Su Chi Wei 
Published: December 2024

ABSTRACTInnovations in environmental technology are essential to address sustainability challenges. This study examines the sustainable development goals (SDGs) relationship with environmental technological innovation (ETI) in EU countries during 2000–2022, using a panel bootstrap causality approach. The result indicates bidirectional causality between SDGs and ETI. Furthermore, the findings indicate that SDGs have a causal impact on ETI in Belgium, Denmark, Germany, the Netherlands, Iceland, Slovakia, Slovenia, and Spain. Similarly, ETI has a significant influence on SDGs in Austria, Estonia, France, Germany, Latvia, the Netherlands, Poland, and Sweden. However, the remaining countries have no causal relationship between SDGs and ETI. The robust results further validate and confirm the reliability of the main findings, supporting the theoretical framework. Policymakers should incorporate the principles of SDGs into national innovation programs, providing targeted financing, incentives, and regulatory frameworks to support initiatives that align with SDGs.
Strategy and Performance of Family Businesses: Comparison of Pakistan and the Czech Republic
Authors: Subhani Muhammad Kamal , Mikušová Marie 
Published: December 2024

ABSTRACTIn this paper, we observe how effective the use of strategies is in relation to the objectives of family businesses. Data collected in spring 2024 by interviews were processed using DEA. Respondents were owners of small family businesses; 169 valid responses were obtained from each country. The assessment reflected the differences between the countries. For Pakistani companies, the human resources management strategy and the growth and expansion strategy were found to be the most valuable and yielded high production. The most frequent outputs were the relationship between the family and their business, as well as family beliefs and religion. In the case of the Czech owner, there is only a strategy of competitiveness that provides equal output. The results here were related to economic performance. An innovative approach is the use of the DEA method, which sets the production‐possibility frontier and thus determines which strategies are currently inefficient.
3‐Chloro‐1,2‐Propanediol Exposure Induces Cardiotoxicity and Behavioural Abnormalities in Zebrafish Embryos
Authors: Wang Jing , Yuan Qiang , Hu Weitao , Ye Zhijun , Zhang Li , Wang Zhipeng , Liu Jiejun , Huang Ling , Liu Fasheng , Liao Xinjun , Xiao Juhua , Zhang Shouhua , Cao Zigang 
Published: December 2024

ABSTRACTNumerous contemporary diseases are linked to food contamination. Pathogenic agents might stem from certain food ingredients or result from pollution stemming from food processing or packaging. One such contaminant is 3‐Chloro‐1,2‐propanediol (3‐MCPD), it has been previously reported to be produced during the preparation of chemical sauces, as well as during the heating of baked goods. Yet, uncertainty surrounds its potential to induce embryonic developmental toxicity. In this study, zebrafish were employed as the focal point to assess the impact of 3‐MCPD on initial embryonic development, heart functionality, and behavior. The research unveiled that exposure of zebrafish embryos to 18, 36, and 54 mM 3‐MCPD led to cardiac anomalies, including pericardial edema, reduced heart rate, and elongated SV‐BA distance. Additionally, 3‐MCPD exposure triggered aberrations in cardiac‐related gene expression and an elevation in oxidative stress. Notably, behavioral changes were observed in 3‐MCPD‐exposed zebrafish embryos, while vascular development appeared unaffected. This study introduces a novel basis for comprehensive exploration of 3‐MCPD toxicity.
Serum Neutrophil Biomarkers to Predict Crohn's Disease Progression and Infliximab Treatment Outcomes
Authors: Magalhaes D. , Santiago M. , Patita M. , Arroja B. , Lago P. , Rosa I. , Sousa H. T. , Ministro P. , Mocanu I. , Vieira A. , Castela J. , Moleiro J. , Roseira J. , Eugenia C. , Sousa P. , Portela F. , Correia L. , Dias S. , Afonso J. , Danese S. , Peyrin‐Biroulet L. , Dias C. C. , Magro F. ,   GEDII
Published: December 2024

ABSTRACTBackground and aimsPredicting the treatment outcomes of biological therapies is an unmet need in Crohn's Disease. In this study, we explored the potential of serum neutrophil‐related biomarkers to predict infliximab therapeutic results and disease progression in Crohn's Disease patients, over a 2‐year period, in a real‐world setting.MethodsThe study included 100 asymptomatic Crohn's Disease patients in the IFX maintenance phase from the prospective, observational, multicenter DIRECT study. Patients were categorized according to a composite outcome reflecting progression that included surgery, hospitalizations, new fistulae, abscess or stricture, and drug treatment escalation. Serum neutrophil elastase, lipocalin‐2, lactoferrin, and resistin (non‐neutrophil control) were analyzed via multiplex magnetic bead assays at multiple touchpoints. Fecal calprotectin was assessed by ELISA.ResultsOver up to 2 years of follow‐up, serum biomarkers did not differentiate between the composite outcome groups, whereas fecal calprotectin was significantly higher in patients with worse outcomes. During the infliximab maintenance phase, there was a significant, sustained reduction of neutrophil elastase (p < 0.001), lipocalin‐2 (p < 0.001), and lactoferrin (p < 0.001), but not of resistin, despite stable neutrophil levels. Correlations between NE and NGAL levels were strong (Pearson correlations 0.75–0.85); all other correlations were of small magnitude.ConclusionOur real‐world data do not support using serum neutrophil elastase, lipocalin‐2, or lactoferrin concentrations as predictors of treatment outcomes or disease evolution in infliximab ‐treated Crohn's Disease patients. On the other hand, the sustained decrease in biomarkers over time suggests that neutrophil stabilization might be an additional infliximab mechanism of action.