bluuebunny/crossref_metadata_2025_split huggingface dataset:
Level of health laboratory service quality, service interruptions, and its predictors in public hospitals in Harar town, eastern Ethiopia
Authors: Zakir Dire , Mekonnen Getachaw Kabew , Negash Belay , Marami Dadi 
Published: November 2024

BackgroundQuality laboratory services are key in the healthcare system for successful diagnosis and patient care. Uninterrupted laboratory services are needed to meet the needs of all patients and clinical personnel, but studies in developing nations revealed that most clinicians were dissatisfied due to the lack of quality laboratory services and frequent interruptions.ObjectiveThis study aimed to assess the level of health laboratory service quality, service interruptions, and its predictors in public Hospitals in Harar town, eastern Ethiopia.MethodA facility-based cross-sectional study was conducted at Hiwot Fana Specialized University Hospital and Jugel General Hospital between January and April 2024. Data collection utilized Standardized Stepwise Laboratory Improvement Process Towards Accreditation (SLIPTA) checklists and questionnaires based on the Ethiopian Hospital Standard Transformation Guidelines. Data were entered and analyzed by Statistical Package for the Social Sciences, version 26. Descriptive statistics such as frequencies, proportions, and means, were calculated. Binary and multivariable logistic regression models were applied to identify predictors with adjusted odds ratio (AOR) and a cut-off p-values &lt;0.05 with 95% confidence interval (CI).ResultsTwo public hospital laboratories and their 54 laboratory professionals were involved in our study. According to our study, the mean score of the two public hospitals was 168.5 (61%), while Hiwot Fana specialized university hospital scored 212 (77%) and Jugel General Hospital scored 127 (46.1%). The study also revealed that out of 72 tests, 31 (43.05%) were interrupted, with clinical chemistry tests being the most interrupted (16, 51.6%) followed by Serology (7, 22.6%) and Hematology (4, 12.9%) tests. Lack of timely management response (AOR = 7.78, 95% CI = 1.48–40.83) and shortage of supplies (AOR = 60.8, 95% CI = 1.07–32.83) were significantly associated predictors of laboratory service interruptions.ConclusionNeither of the hospital's laboratories met the required score of the SLIPTA standard for quality clinical laboratory services. Moreover, laboratory service interruptions were very common in the two public hospitals in which clinical chemistry, serology and hematology tests were the most frequently interrupted. Shortage of reagents and supplies and inefficient laboratory management are the major causes of service interruptions. So, policymakers and other stakeholders should support continuous quality improvement for a better patient clinical outcome.
The ability of the Lab4 probiotic consortium to impact upon the functionality of serum deprived human keratinocytes in vitro
Authors: Thomas Sophie E. , Kerry-Smith Joshua , Plummer Susan F. , Bate Jack P. , John Daniel A. , Lawrence Evie , Powell Lydia , Dally Jordanna , Moseley Ryan , Michael Daryn R. 
Published: November 2024

IntroductionDysfunction of keratinocytes contributes to a weakened skin barrier and impaired wound healing capability. Evidence suggests that probiotic supplementation can lead to improved skin function in vitro and in vivo. The Lab4 probiotic consortium comprises of two strains of Lactobacillus species and two strains of Bifidobacterium species.MethodsUsing serum deprived conditions to impair the functionality of immortalized human HaCaT keratinocytes, this study aimed to assess the impact of metabolites derived from the Lab4 probiotic consortium on keratinocyte function.ResultsA significant improvement in HaCaT metabolic activity and lower apoptotic activity was observed in tandem with a reduction in Caspase-3 gene expression and a lower Bax/Bcl2 ratio following the addition of Lab4. The probiotic also supported barrier integrity which was better maintained with a significant increase in Filaggrin gene expression. In damaged keratinocytes, Lab4 enhanced rates of re-epithelialization, which were associated with significantly increased gene expression of MMP-1 and enhanced secretion of IL-6 and IL-8.DiscussionThese results suggest that the Lab4 probiotic consortium may have the ability to benefit the functionality of skin.
Genome-Wide Identification and Stress Responses of Cowpea Thaumatin-like Proteins: A Comprehensive Analysis
Authors: Jesús-Pires Carolline de , Ferreira-Neto José Ribamar Costa , Oliveira-Silva Roberta Lane de , Silva Jéssica Barboza da , Silva Manassés Daniel da , Costa Antônio Félix da , Benko-Iseppon Ana Maria 
Published: November 2024

Cowpea (Vigna unguiculata (L.) Walp.) is an important legume cultivated mainly in regions with limited water availability across the African and American continents. Its productivity is significantly affected by environmental stresses. Thaumatin-like proteins (TLPs), which belong to the PR-5 (pathogenesis-related 5) protein family, are known to be responsive to both biotic and abiotic stresses. However, their role remains controversial, with some TLPs associated with plant defense (particularly against fungal infections) and others associated with abiotic stresses response. In this study, we evaluated the structural diversity and gene expression of TLPs in cowpea (VuTLPs) under different stress conditions, including biotic [mechanical injury followed by inoculation with Cowpea Aphid-borne Mosaic Virus (CABMV) or Cowpea Severe Mosaic Virus (CPSMV)] and abiotic (root dehydration). Genomic anchoring of VuTLPs revealed 34 loci encoding these proteins. Neighbor- joining analysis clustered the VuTLPs into three distinct groups. We identified 15 segmental duplication and 6 tandem duplication gene pairs, with the majority of VuTLP genes found to be under purifying selection. Promoter analysis associated VuTLPs with bHLH, Dof-type, and MYB- related transcription factors, supporting their diverse roles. Diversity in VuTLP function was also observed in their expression profiles under the studied stress conditions. Gene expression data showed that most VuTLPs are recruited within the first minutes after biotic stress imposition. For the root dehydration assay, the most transcripts were up-regulated 150 min post-stress. Moreover, the gene expression data suggested that VuTLPs exhibit functional specialization depending on the stress condition, highlighting their diverse roles and biotechnological potential.
Global Policy and Advocacy Initiatives for Improving Kidney Care
Authors: Wainstein Marina , Tiv Sophanny , Arruebo Silvia , Caskey Fergus J. , Damster Sandrine , Donner Jo-Ann , Gouda Zaghloul , Jha Vivekanand , Levin Adeera , Nangaku Masaomi , Saad Syed , Ye Feng , Okpechi Ikechi G. , Bello Aminu K. , Johnson David W. , Luyckx Valerie A. 
Published: November 2024

Background:
National strategies to address chronic kidney disease (CKD) are crucial to support kidney health. Lack of political support in the form of policy decisions and funding leads to fragmentation of kidney care and catastrophic health expenditure. This study used data from the third iteration of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA) to obtain a global overview of the existence and reach of national strategies for kidney care.

Methods:
We leveraged data from an international survey of stakeholders (clinicians, policymakers, and patient advocates) conducted by the ISN between July and September 2022. Data were extracted on existence and scope of national non-communicable disease (NCD) and/or CKD-specific strategies and policies, as well as recognition of kidney disease as a national health priority through participant perception and existence of CKD advocacy groups.

Results:
Overall, stakeholders from 167 countries responded to the survey representing 97.4% of the global population. National strategies for NCDs were reported by 56% of countries. In 29% of countries CKD was addressed within an NCD strategy while 25% of countries reported CKD-specific strategies. Countries with CKD-specific strategies were more likely to address all CKD populations (non-dialysis dependent CKD, chronic dialysis and kidney transplantation) compared to those with NCD strategies only (51.2% versus 19%). Of the 54% of countries with any CKD strategy 89% reported public funding of the full spectrum of CKD care compared to 64% of those with no CKD strategy. KF, CKD and AKI were reported to be recognized as national health priorities by 63%, 48% and 19% of countries respectively.

Conclusions:
The inclusion of CKD and kidney failure within national health strategies is frequently lacking. Countries with CKD-specific policies tend to include a broader spectrum of kidney disease populations and to fund kidney care more than those with CKD policies integrated within NCD strategies. Greater global and national prioritization of kidney health are required to reduce global inequities in access to kidney care.
Metodologias ativas e uso de estratégias de leitura como ferramentas pedagógicas de potencialização da aprendizagem
Authors: Ribeiro Ademilson Pereira , Silva Anderson Ferreira da , Araújo Ana Carla de , Carvalho Júlia Correa , Vicente Tatiane do Carmo Vieira 
Published: November 2024

Nos dias atuais, fica evidente a necessidade de soluções modernas para a educação, o que não poderia ser diferente. Nesse sentido, muitas metodologias ativas estão sendo propostas para que as aulas, em particular de leitura, possam ficar mais significativas para as crianças e jovens de modo geral. Dentre essas, o uso de estratégias de leitura e metodologias ativas se apresentam como uma boa resposta para aumento de rendimento escolar dos alunos. Objetivo: objetivou-se com esse artigo verificar se houve ganho no rendimento dos alunos 5º e 6º anos, ensino fundamental de uma escola pública, na cidade de Campos Gerais/MG. Metodologia: as atividades desta pesquisa forma, em primeiro lugar, centradas na busca bibliográfica, realizada com buscas no SciELO Brasil e google acadêmico, cuja amostra utilizada foi de 48 trabalhos sendo 3 teses, 30 dissertações e 15 artigos publicados em periódicos, no período de 20 de dezembro de 2023 a 21 de abril de 2024. Em um segundo momento, foi realizada uma análise documental, com foco no planejamento e nos arquivos resultantes da aplicação das atividades de leitura realizadas em sala e anotações feitas nos portfólios de trabalhos encontrados na escola. Resultados e Discussão: vinculados as observações que foram realizadas durante esta pesquisa, os dados apontam no sentido de o esforço de emprego das metodologias ativas se justifica por apresentar, ao lado do uso eficaz das estratégias de leitura, uma potencialização a favor da aprendizagem efetiva na escola e não gerar uma guerra entre alunos e métodos de ensino e aprendizagem utilizados pelos jovens, ou seja, falar a mesma língua que eles estão falando. Conclusão: Os dados obtidos, demonstraram a importância de se empregar metodologias ativas e estratégias de leitura. Quando se analisa no final de cada bimestre os portfólios de trabalhos e avalições, verifica-se um ganho significativo, em média, no aprendizado e rendimento quantitativos dos alunos. Por fim, deve-se ressaltar que as metodologias ativas e estratégias de leitura são ferramentas pedagógicas que devem ser aplicadas, reforçando fato o aprendizado integrado e transversal, além de evitar que os alunos fiquem presos a atividades maçantes e repetitivas.
Испытание полевых приборов, применяемых при осмотре места пожара в условиях низких температур, на работоспособность с помощью климатической камеры
Authors: А.В. Калач , Т.П. Сысоева , С.Ф. Лобова 
Published: November 2024

Авторами обосновано, нецелесообразность применения полевых приборов для осмотра места пожара в условиях отрицательных температур, с помощью проведенных испытаний в климатической камере. В ходе испытаний также было установлено, что только один прибор «КОЛИОН-1А», работает в соответствии с температурным диапазоном, указанным в техническом паспорте. Температурные характеристики остальных приборов «МВП-2М», «КИМ-01-ЭП», «УЗ-01-ЭП», «ТМ 4», не соответствуют техническим паспортам.
The authors have justified the inexpediency of using field instruments to inspect the fire site in conditions of negative temperatures, with the help of tests conducted in a climatic chamber. During the tests, it was also found that only one device "KOLION-1A" works in accordance with the temperature range specified in the technical data sheet. The temperature characteristics of the other devices "MVP-2M", "KIM-01-EP", "UZ-01-EP", "TM 4" do not correspond to the technical data sheets.
О необходимости формирования инструментов оценки профилактических мероприятий при прогнозировании паводкоопасной обстановки в геоинформационных системах
Authors: С.Н. Молодец 
Published: November 2024

В данной статье рассматривается проблема необходимости формирования специальных инструментов оценки профилактических мероприятий для более точного прогнозирования паводкоопасной обстановки. В работе детально анализируются нормативные правовые акты по выявлению и классификации профилактических мероприятий, связанных с паводкоопасной обстановкой, а также виды информационных массивов, необходимых для применения геоинформатики в разработке и реализации инструментов по расчету и оценке эффективности мер для предотвращения негативных последствий наводнений.This article considers the problem of necessity of formation of special tools for assessment of preventive measures for more accurate forecasting of flood hazardous situation. The paper analyzes in detail normative-legal documents for identification and classification of preventive measures related to flood hazardous situation. The paper analyzes in detail the types of information arrays necessary for the application of geoinformatics in the development and implementation of tools for calculating and assessing the effectiveness of measures to prevent the negative consequences of floods.
Профилактика спортивного травматизма среди курсантов уральского института ГПС МЧС России
Authors: В.В. Башаров , В.В. Верхотуров 
Published: November 2024

В статье рассмотрен анализ травм курсантов Уральского института ГПС МЧС России. Рассмотрены основные причины и обстоятельства, приводящие к спортивным травмам, указывается характер и тяжесть повреждений. Обсуждается компетентностный подход при проведении занятий по физической культуре и спорту среди курсантов института. Построена причина-следственная модель, которая позволяет предложить комплекс профилактических мероприятий, направленных на снижение спортивного травматизма среди курсантов. Особое внимание при построении модели уделено управлению качеством проведению занятий и контролю соблюдения профилактических мероприятий.
The article deals with the analysis of injuries of cadets of the Ural Institute of the state fire service of the Ministry of emergency situations of Russia. The main causes and circumstances leading to sports injuries are considered, and the nature and severity of the injuries are indicated. The author discusses the competence approach to conducting physical culture and sports classes among the Institute’s cadets. A causal model is constructed that allows us to offer a set of preventive measures aimed at reducing sports injuries among cadets. Special attention is paid to quality management conducting classes and monitoring compliance with preventive measures
Вопросы обоснования ресурсной потребности территориальных подразделений пожарной охраны
Authors: В.В. Харин , Е.В. Бобринев , Е.Ю. Удавцова , А.А. Кондашов 
Published: November 2024

Описан механизм формирования ресурсной потребности территориальных подразделений пожарной охраны. Проанализированы различные способы оценки уровня пожарной опасности территорий. Изучены факторы, влияющие на состояние ресурсов территориальных подразделений пожарной охраны. Предложен подход, в котором для оптимального состояния ресурсов пожарной охраны с целью нейтрализации порождающих пожарную опасность факторов количество основных пожарных автомобилей поставлено в зависимость от уровня пожарной опасности в районе выезда подразделения пожарной охраны.
The mechanism of forming the resource needs of territorial fire departments is described. Various ways of assessing the level of fire danger of territories are analyzed. The factors influencing the state of resources of territorial fire protection units are studied. The analysis of the existing legal framework for the organization of fire fighting and emergency rescue operations. An approach is proposed in which for the optimal state of fire protection resources in order to neutralize the factors that generate fire danger, the number of main fire vehicles is dependent on the level of fire danger in the area of departure of the fire protection unit.
Результаты, полученные при внедрении электрофильтра в систему вентиляции комбикормового завода для предотвращения пылевых взрывов
Authors: Д.А. Едимичев , А.Н. Минкин , С.Н. Масаев , Я.А. Тарасова 
Published: November 2024

Работа посвящена вопросам эффективности использования техники электрической фильтрации и пылеудаления на пожаровзрывоопасных объектах, характеризуемых повышенным содержанием пыли и горючих волокон, на примере Красноярского комбикормового завода. В статье представлены результаты опытного применения электрофильтра в системе вентиляции комбикормового завода, доказывающие возможность его безопасного применения и высокую степень очистки запылённого воздуха, что позволит значительно снизить риск возникновения первичных и вторичных пылевых взрывов. Также в статье приводится описание устройства предлагаемого электрофильтра, позволяющего обеспечить процесс пылеудаления в пожаровзрывоопасных помещениях, отличающихся повышенной концентрацией в воздухе органической, мелкодисперсной пыли. Результаты работы могут быть использованы при проектировании электрофильтров, учитывая местные свойства улавливаемых пылей, их состав, дисперсность и производительность установленной вентиляционной системы. Полученные результаты также могут быть использованы при разработке методических рекомендаций, направленных на определение оптимальных режимов работы электрофильтров, инструкций по их безопасной эксплуатации
The work is devoted to the issues of the efficiency of using electrical filtering and dust removal equipment at fire and explosion hazardous objects of high content of dust and combustible fibers, for example of the Krasnoyarsk feed mill. The article presents the results of the pilot application of an electrostatic precipitator in the ventilation system of a feed mill, proving the possibility of its safe use and a high degree of dusty air purification, which will significantly reduce the risk of primary and secondary dust explosions. Also, the article provides a description of the device of the proposed electrostatic precipitator, which allows for the process of dust removal in fire-hazardous premises, characterized by an increased concentration of organic fine dust in the air. The results of the work can be used in the design of electrostatic precipitators, taking into account the local properties of the captured dusts, their composition, dispersion, and performance of the installed ventilation system. Also, the results of experimental use can be used in the development of methodological recommendations aimed at determining the optimal operation modes of electrostatic precipitators, instructions for their safe operation.
Современные аспекты обеспечения огнестойкости строительных конструкций
Authors: А.В. Калач , Е.В. Калач , Н.М. Лоран 
Published: November 2024

В статье представлен анализ современного состояния обеспечения огнестойкости строительных конструкций. Отдельное внимание уделено направлениям совершенствования способов обеспечения огнестойкости строительных конструкций, зданий и сооружений. Показана особое значение фактической огнестойкости ограждающих конструкций здания в обеспечении противопожарной защиты объекта.
The article presents an analysis of the modern state of fire resistance of building structures. Special attention is paid to the directions of improvement of methods of fire resistance of building structures, buildings and structures. The special value of the actual fire resistance of the building enclosing structures in providing fire protection of the object is shown.
Определение параметров динамического радиационного контроля в акваториях
Authors: И.Ю. Сергеев , Н.П. Валуев 
Published: November 2024

Описана методика определения параметров динамического радиационного контроля в акваториях рек и крупных водоемов. Контроль основан на применении высокочувствительных дозиметрических систем, регистрирующих γ-излучение в процессе движения системы по акватории. Это позволяет обнаруживать выход радионуклидов из зоны их локализации и стоков, прогнозировать и прослеживать пути их движения по акватории рек, а также обнаруживать радиационные аномалии по берегам, в портах, плавсредствах, движущихся в акваториях.
Methods definition of dynamic radiation control parameters in surfaces of rivers and large water bodies is described. Methodsbased on application of highly sensitive dosimetric systems registering γ-radiation of water in the process of system movement along the water area. Methods allows detecting the exit of radionuclides from the zone of their location and runoff, to forecast and trace the paths of their movement in the surfaces of rivers, detecting radioactive source on the shore, in ports, ships in water area.
Методика оценки распространения нефтяных загрязнений по почвенному покрову, с учетом его характеристик и возможностью установления тип загрязнения, для прогнозирования развития чрезвычайной ситуации на объектах нефтегазового комплекса
Authors: Н.В. Елфимов 
Published: November 2024

В статье представлена методика оценки распространения нефтяного загрязнения по почвенному покрову с учетом его характеристик и возможностью установления типа загрязнения с помощью капельно-люминесцентного метода. Применение данного метода позволяет непосредственно на месте чрезвычайной ситуации оперативно определить наличие в почве нефти и нефтепродуктов и их количество, что является одним из решающих факторов для принятия решений по ликвидации последствий. Также для решения вопроса идентификации загрязнений, привнесенных в почву, предлагается использовать математическую обработку полученных объемных спектров люминесценции. В качестве критерия сравнения предлагается использовать расчетный критерий (ТА), который позволит провести расчёт как при суммировании полученных значений по регистрации, так и по возбуждению.
The article presents a methodology for estimating the distribution of oil pollution on the soil cover taking into account its characteristics and the possibility of establishing the type of pollution using the drip-luminescent method. The application of this method makes it possible to quickly determine the presence and quantity of oil and petroleum products in the soil at the emergency site, which is one of the decisive factors for making decisions on the elimination of consequences. Also, to solve the issue of identifying contaminants introduced into the soil, it is proposed to use mathematical processing of the obtained volumetric spectra of luminescence. As a comparison criterion, it is proposed to use the calculation criterion (TA), which will allow calculating both when summing up the obtained values by registration and excitation.