bluuebunny/crossref_metadata_2025_split huggingface dataset:
El impacto de las Tecnologías de la Comunicación y la Información en los procesos cognitivos humanos. Implicaciones para la naturaleza humana
Authors: Lumbreras Sara , Moreno Ana , Latorre Jesús 
Published: March 2018

Las Tecnologías de la Comunicación y la Información (TCIs) han cambiado drásticamente la manera en la que accedemos al conocimiento y procesamos datos, cómo aprendemos y trabajamos y nuestra manera de relacionarnos con otros seres humanos. El interés creciente que despiertan las consecuencias del uso de las TCIs se ha manifestado en múltiples estudios aislados que analizan estos fenómenos desde puntos de vista diferentes. Este artículo tiene como objetivo proporcionar una perspectiva unificadora de estos trabajos, reflexionando sobre las consecuencias que el uso de las TCI está teniendo en nuestras habilidades intelectuales y en cómo nos percibimos a nosotros mismos como seres humanos.
Anotaciones sobre la ciencia y la fe a la luz de la epistemología actual
Authors: Prieto López Leopoldo José 
Published: March 2018

La ciencia ha sido utilizada frecuentemente como instrumento de refutación de la religión. El intento más decidido en esta dirección lo ha realizado el positivismo, que identificando ciencia y verdad, declaraba falsas las afirmaciones de la religión. El neopositivismo, posteriormente, apelando al principio de verificación empírica, en lugar de declarar falsas las posiciones de la religión, las considera carentes de sentido. La actual epistemología, sin embargo, ha criticado el uso que se hace de dicho principio. Así pues, el staus quaestionis actual sobre la relación ente ciencia y fe se asienta sobre dos fundamentos: si, de un lado, las diferencias de objeto, método y fines entre ciencia y religión hacen lógicamente imposible una refutación de la religión por la ciencia, de otro lado, la misma ciencia admite la existencia de un espacio abierto para garantizar una certeza (fundada en la fe) que ella misma no es capaz de proporcionar.
Cereblon Maintains Synaptic and Cognitive Function by Regulating BK Channel
Authors: Choi Tae-Yong , Lee Seung-Hyun , Kim Yoon-Jung , Bae Jae Ryul , Lee Kwang Min , Jo Youhwa , Kim Soo-Jeong , Lee A-Ram , Choi Sekyu , Choi La-Mee , Bang Sunhoe , Song Mi-Ryoung , Chung Jongkyeong , Lee Kyung Jin , Kim Sung Hyun , Park Chul-Seung , Choi Se-Young 
Published: March 2018

Mutations in thecereblon(CRBN) gene cause human intellectual disability, one of the most common cognitive disorders. However, the molecular mechanisms ofCRBN-related intellectual disability remain poorly understood. We investigated the role ofCRBNin synaptic function and animal behavior using male mouse andDrosophilamodels.Crbnknock-out (KO) mice showed normal brain and spine morphology as well as intact synaptic plasticity; however, they also exhibited decreases in synaptic transmission and presynaptic release probability exclusively in excitatory synapses. Presynaptic function was impaired not only by loss of CRBN expression, but also by expression of pathogenic CRBN mutants (human R419X mutant andDrosophilaG552X mutant). We found that the BK channel blockers paxilline and iberiotoxin reversed this decrease in presynaptic release probability inCrbnKO mice. In addition, paxilline treatment also restored normal cognitive behavior inCrbnKO mice. These results strongly suggest that increased BK channel activity is the pathological mechanism of intellectual disability inCRBNmutations.SIGNIFICANCE STATEMENTCereblon(CRBN), a well known target of the immunomodulatory drug thalidomide, was originally identified as a gene that causes human intellectual disability when mutated. However, the molecular mechanisms of CRBN-related intellectual disability remain poorly understood. Based on the idea that synaptic abnormalities are the most common factor in cognitive dysfunction, we monitored the synaptic structure and function ofCrbnknock-out (KO) animals to identify the molecular mechanisms of intellectual disability. Here, we found thatCrbnKO animals showed cognitive deficits caused by enhanced BK channel activity and reduced presynaptic glutamate release. Our findings suggest a physiological pathomechanism of the intellectual disability-related geneCRBNand will contribute to the development of therapeutic strategies forCRBN-related intellectual disability.
Zapata reactivado: una visión žižekiana del Centenario de la Constitución
Authors: Centeno Ramón I. 
Published: March 2018

La Constitución de 1917 ha cumplido cien años. Su principal innovación, producto de la guerra civil en curso, fue la gestación de un constitucionalismo social, plasmado en los artículos 3, 27 y 123. Cien años después, el potencial emancipatorio implicado en esos artículos ha sido revocado en la práctica política de México. Este ensayo da sustento a la anterior afirmación, pero también sugiere una ruta para rehabilitar la justicia social. Inspirado en la crítica de la ideología de Žižek, sostengo que hay que volver a empezar, hay que repetir a Zapata; esto es, hay que recuperar, para la época actual, el tipo de intervención capaz de imponer nuevas coordenadas para la reinvención política del país.
The Constitution of 1917 is now one hundred years old. Its primary innovation, a product of the ongoing civil war, was the development of a social constitutionalism, as expressed in articles 3, 27 and 123. One hundred years later, the emancipatory potential implied in these articles has been eliminated from political practice in Mexico. This essay substantiates this assertion, but also suggests a way to regenerate social justice. Inspired by Žižek's critique of ideology, I propose that we must begin from the beginning, we must repeat Zapata; in other words, we must retrieve, for our present moment, the type of intervention capable of infusing new directions to enable the political reinvention of the country.
Reflections on The Possibility of Using Statistical Analysis Science and Innovation in The Republic of Moldova
Authors: Aurelia Turcan (Susu) 
Published: March 2018

The evaluation and comparability of statistics indicators of the science and innovation on international background reflect country competitiveness and it position regarding field of science, innovation and distribution of new technologies. Better comprehensions of the factors that contribute at the success in these fields are helped by using proper indicators like instruments of identification of the best practice. But the system of indicators is developed only for the ”science”. The ”innovation” in Moldova is not covered by statistical work and can only be assessed indirectly.
Relationship maternal subcutaneous adipose tissue thickness and development of gestational diabetes mellitus
Authors: Kansu-Celik Hatice , Karakaya Burcu Kisa , Tasci Yasemin , Hancerliogullari Necati , Yaman Selen , Ozel Sule , Erkaya Salim 
Published: March 2018

Objective
We investigated whether the ultrasonographic measurement of maternal subcutaneous adipose tissue (SAT) thickness in the second trimester played a role in predicting gestational diabetes.

Materials and methods
This was a prospective cross-sectional study in which 223 women were classified as healthy (n = 177) or as gestational diabetes (n = 46) on the basis of a negative or positive two-step oral Glucose Challenge Test (GCT), respectively. The depth of the abdominal SAT was evaluated by two-dimensional ultrasonography. Body mass index (BMI), waist circumference (WC), and waist/hip ratio were determined.

Results
There was a positive strong significant correlation between a 50-g GCT level and BMI, WC, and SAT thickness (p < 0.001). Receiver-operating characteristic curve analysis showed SAT thickness above 16.75 mm predicted gestational diabetes mellitus (GDM) with a sensitivity of 71.7%, a specificity of 57.1%, a positive predictive value of 32.3%, and a negative predictive value of 87.6%. There was a good correlation between SAT, BMI, and WC.

Conclusion
Increased SAT, BMI, and WC measurements may be helpful in predicting the risk of the development of GDM in pregnant women.
Risk factors contributing to gingival recession among patients undergoing different orthodontic treatment modalities
Authors: Sawan Nozha Mahmoud , Ghoneima Ahmed , Stewart Kelton , Liu Sean 
Published: March 2018

Objective
The aim of this study was to investigate the risk factors contributing to gingival recession among patients undergoing orthodontic treatment.

Methods
Records of 100 Caucasian patients who completed orthodontic treatment were evaluated before and after treatment. Intercanine and molar widths, arch perimeter, arch depth, and keratinized gingival height were measured for both arches. The association of orthodontic treatment strategy (changing incisal inclination, expansion, and extraction), keratinized gingival height, and various other measurements with gingival recession was evaluated by using generalized linear mixed models with logistic regression analysis.

Results
For each 1 mm increase in pre- and post-treatment keratinized gingival height, there was 0.77 and 0.51 times lower odds of gingival recession. For each 1 mm increase in post-treatment intercanine width, there was 0.80 times lower odds of gingival recession. And for each 1 mm increase in change in the arch depth, there was 1.16 times higher odds of gingival recession. For each 1 mm increase in pre- and post-treatment mandibular symphysis width, there was 0.47 and 0.39 times lower odds of gingival recession.

Conclusion
Regardless of the type of orthodontic treatment, increased keratinized gingival height, mandibular symphysis width, and post-treatment intercanine width lower the risk of gingival recession.
Architecture based in open source hardware and software for designing a real time vehicle tracking device
Authors: Castillo Rodríguez Diony Roely , Martínez Laguardia Alain Sebastián , Gómez Abreu Alberto 
Published: March 2018

The usage of real-time tracking systems for vehicles has demonstrated to be a viable and economical option, entailing in more control and management of the fleet, plus the reduction of the logistics costs of companies using them. Since 2006 in Cuba, there is a fleet control and management system employed by almost all the companies, which hire a variant of the service in a differed manner; i.e., the data are not processed in real-time. In this research paper, we propose the design of a device based only on open source hardware/software components allowing the real-time vehicle tracking. Our proposal is suitable for the conditions of the country where it was developed (Cuba), presenting high functionality than other proposals. For the design, we employed an Arduino UNO controller board, an Adafruit FONA808 GPS/GSM module, and other accessories. As per the performed experiments, the proposed hardware/software architecture complies with the operation, configuration, and security requirements to achieve a viable product from the economical and environmental approaches.
Regional resting state perfusion variability and delayed cerebrovascular uniform reactivity in subjects with chronic carotid artery stenosis
Authors: Szarmach Arkadiusz , Kaszubowski Mariusz , Sabisz Agnieszka , Frydrychowski Andrzej F , Halena Grzegorz , Piskunowicz Maciej , Dzierzanowski Jaroslaw , Studniarek Michal , Szurowska Edyta , Winklewski Pawel J 
Published: March 2018

The aim of this study was to assess regional perfusion at baseline and regional cerebrovascular resistance (CVR) to delayed acetazolamide challenge in subjects with chronic carotid artery stenosis.Sixteen patients (ten males) aged 70.94±7.71 with carotid artery stenosis ≥90% on the ipsilateral side and ≤50% on the contralateral side were enrolled into the study. In all patients, two computed tomography perfusion examinations were carried out; the first was performed before acetazolamide administration and the second 60 minutes after injection.The differences between mean values were examined by paired two-sample t-test and alternative nonparametric Wilcoxon’s test. Normality assumption was examined using W Shapiro-Wilk test.The lowest resting-state cerebral blood flow (CBF) was observed in white matter (ipsilateral side: 18.4±6.2; contralateral side: 19.3±6.6) and brainstem (ipsilateral side: 27.8±8.5; contralateral side: 29.1±10.8). Grey matter (cerebral cortex) resting state CBF was below the normal value for subjects of this age: frontal lobe – ipsilateral side: 30.4±7.0, contralateral side: 33.7±7.1; parietal lobe – ipsilateral side: 36.4±11.3, contralateral side: 42.7±9.9; temporal lobe – ipsilateral side: 32.5±8.6, contralateral side: 39.4±10.8; occipital lobe – ipsilateral side: 24.0±6.0, contralateral side: 26.4±6.6). The highest resting state CBF was observed in the insula (ipsilateral side: 49.2±17.4; contralateral side: 55.3±18.4). A relatively high resting state CBF was also recorded in the thalamus (ipsilateral side: 39.7±16.9; contralateral side: 41.7±14.1) and cerebellum (ipsilateral side: 41.4±12.2; contralateral side: 38.1±11.3). The highest CVR was observed in temporal lobe cortex (ipsilateral side: +27.1%; contralateral side: +26.1%) and cerebellum (ipsilateral side: +27.0%; contralateral side: +34.6%). The lowest CVR was recorded in brain stem (ipsilateral side: +20.2%; contralateral side: +22.2%) and white matter (ipsilateral side: +18.1%; contralateral side: +18.3%). All CBF values were provided in milliliters of blood per minute per 100 g of brain tissue [ml/100g/min]. Resting state circulation in subjects with carotid artery stenosis is low in all analysed structures with the exception of insula and cerebellum. Acetazolamide challenge yields relatively uniform response in both hemispheres in the investigated population.Grey matter is more reactive to acetazolamide challenge than white matter or brainstem.
Trabajo en equipo: de la teoría a la cultura institucional
Authors: Pintos Artigas María Ema , Martínez Sagasta Fernando 
Published: March 2018

Quienes realizamos este estudio, Coordinadores Adscriptos en el área de 5º y 6º año de bachillerato de una institución educativa privada, trabajamos desde hace veinte años en la formación, seguimiento y acompañamiento personal y grupal de sus estudiantes. Nuestras experiencias en el ámbito de la misma, nos permite percibir que los distintos educadores que integramos los diferentes campos disciplinares, cuando nos reunimos para trabajar en equipo, en reiteradas oportunidades lo hacemos en grupos separados, especialmente con relación a nuestras disciplinas, o, adoptando formas limitadas, en el sentido de que los educadores no ejercemos la enseñanza conjunta dentro del aula. Se trata de un trabajo en equipo que se concentra en lo inmediato, en el corto plazo y excluye los problemas de planificación del plazo más largo, o de una forma impuesta o más dirigible, que es buena para cuando se inicia en la modalidad de trabajo en equipo, pero que no es deseable se extienda en el tiempo, -lo que constatamos ocurre en ocasiones-. Frente a estas percepciones deseamos indagar cómo estamos interactuando los educadores en los diferentes equipos de trabajo.Consideramos al trabajo en equipo como enriquecedor de los procesos educativos y le otorgamos gran importancia a su proyección en el tiempo, por esto pensamos que nuestro aporte puede colaborar en que se llegue a esta toma de conciencia, e ir poco a poco, transformando la teorización del tema en una verdadera cultura de trabajo en equipo. Nuestro propósito, pues, es indagar si el trabajo en equipo es favorecido o no, por la interacción entre los educadores. Para orientar nuestro estudio nos planteamos la siguiente interrogante: ¿la interacción entre los educadores favorece o no, el trabajo en equipo en 5º y 6º año de bachillerato de la institución en que trabajamos? Abordando aspectos que surgen de esta pregunta y que sirven como aproximación, la desagregamos en: ¿quién determina los equipos?, ¿para qué funcionan?, ¿cómo están funcionando?, ¿qué tipo de equipos trabajan?, ¿qué logros alcanzan estos equipos?
Effect of Proteolytic Agents on Microleakage of Etch and Rinse Adhesive Systems
Authors: Kasraei Shahin , Yarmohammadi Ebrahim , Farhadian Maryam , Malek Mona 
Published: March 2018

Objective: this study aimed to assess the effect of treatment of phosphoric acid etched dentin surface with 5% bromelain enzyme and Nd:YAG laser prior to the use of etch and rinse adhesive systems on microleakage margins of class V composite restorations. Materials and Methods: sixty sound premolar teeth were selected. Standard class V cavities were prepared in the buccal and lingual surfaces of each teeth. Preparation in that way 1 mm of the cavity was above and 1 mm of it was below the cementoenamel junction. The teeth were then randomly divided into three groups including 20 teeth(40cavities in each gorup). Two ethanol base etch and rinse system (Adper Single Bond and OptiBond Solo) was applied in each group. In the control group, cavities were etched with 37% phosphoric acid. Adper Single Bond was applied to 20 and OptiBond Solo was applied to the remaining 20 cavities and they were restored with Z250 composite (n=40). The same procedures were performed in bromelain and Nd:YAG laser groups with the difference that prior to the application of adhesive, aqueous 5% bromelain was applied in bromelain group while Nd:YAG laser was irradiated in laser group. All teeth were thermocycled and their apices were sealed with sticky wax. The tooth surfaces were coated with nail varnish except for 1 mm around the restoration margins, and the teeth were then immersed in fuchsine and sectioned by a diamond disc into mesial and distal halves. Marginal microleakage at both sides was determined and scored under a stereomicroscope at x40 magnification. Then data were analyzed using the Kruskal Wallis and Mann Whitney tests (α=0.05). Results: according the result of Mann Whitney test, Cervical margins showed significantly higher microleakage than the occlusal margins (P=0.000) but no significant difference was noted in microleakage of occlusal (P=0.362) or gingival (P=0.147) margins among the three groups by Kruskal Wallis test. Conclusion: in conclusion, application of proteolytic agents(5% bromelain solution and Nd:YAG laser) on acid-etched dentin surface prior to the application of adhesive has no significant effect on marginal microleakage of class V composite restorations.
Satisfacción con la vida en escolares de la ciudad de Arequipa
Authors: Arias Gallegos Walter Lizandro , Huamani Cahua Julio Cesar , Caycho-Rodríguez Tomás 
Published: March 2018

<p>El presente estudio, que se enmarca dentro de la Psicología Positiva Educativa, tiene dos objetivos, analizar psicométricamente la Escala de Satisfacción con la Vida, y comparar los valores resultantes en función del sexo, la edad y la institución de procedencia, en un grupo de escolares de la ciudad de Arequipa. Se trabajó con una muestra de 872 estudiantes de 4to y 5to de media de cinco escuelas de gestión mixta y diferenciada, donde el 46.9% son varones y el 53.1% mujeres, obtenida por métodos probabilísticos. Se utilizó la Escala de Satisfacción con la Vida de Diener. Los resultados indican que la prueba cuenta con una estructura factorial unidimensional y una confiabilidad adecuada para variables latentes, (ω= .99 y H= .99). Las comparaciones efectuadas sugieren que los varones y los estudiantes de mayor edad presentan niveles mayores de satisfacción con la vida. </p>
KAJIAN EKOLOGI, KEANEKARAGAMAN JENIS DAN POTENSI POHON DI PEKARANGAN (STUDI KASUS DI DESA KEBAK, JUMANTONO, KARANGANYAR)
Authors: Susanto Arief , Muliawati Endang Setya , Purnomo Djoko 
Published: March 2018

<p><em>Homegarden is one alternative that multipurpose agricultural land to cope with reduced land resources. This study aimed to determine the characteristics of the ecology, species diversity and potential of trees in the homegarden that is useful in further development. The research </em><em>had been </em><em>conducted </em><em>in </em><em>June</em><em> to August 2011 in the Kebak Village, Jumantono District, Karanganyar Regency</em><em> </em><em>with a </em><em>altitude of </em><em>330</em><em> meters above sea level and soil type alvisol. </em><em>This</em><em> experiment </em><em>used</em><em> survey methods with observation unit is divided into three categories based on the size of the homegarden: narrow (&lt;700 m<sup>2</sup>), medium (700-900 m<sup>2</sup>) and large (&gt; 900 m<sup>2</sup>). Observed variables include three aspects: biological variables (type and number of trees, tree height, trunk diameter and canopy area), physical variables (analysis of soil, microclimate homegarden, macroclimate and physiographic land) and analysis of the vegetation (density, frequency, dominance, relative density, relative frequency, relative dominance, importance value index and the index of species diversity). Kebak village had been 40 species of trees are divided into fruit trees, timber, vegetable producers, growers and others. The results showed indicate that the type of fruit tree had the largest of 20 species by the reached 142 tree to rambutan tree. Spacious homegarden area had the highest type and number of trees as well as the highest species diversity index.</em></p><p> </p>
BUDIDAYA CABAI RAWIT SISTEM HIDROPONIK SUBSTRAT DENGAN VARIASI MEDIA DAN NUTRISI
Authors: Purnomo Djoko , Harjoko Dwi , Sulistyo Trijono Djoko 
Published: March 2018

<div class="WordSection1"><p><em>The study aimed to determine which substrate and nutrition that gives the best result in improving growth and yield of </em><em>Capsicum frutescens</em><em>. The study design using CRD (completely randomized design) with two factors, namely substrates (6 levels: charcoal husks, fractional tiles, fractional bricks, arenga fiber, beach sand, husk steamed) and nutrition (2 levels: standards, standards with NPK). The study was conducted October 2015 until March 2016 in screen house Faculty of Agriculture, Sebelas Maret University. Data were analyzed using analysis of variance and if significant difference continued with DMRT (Duncan Multiple Range Test) level of 5%. The results showed that the kinds of substrates significantly affect all variables of </em><em>Capsicum frutescens</em><em> (plant height, leaf number, branch number, total interest, diameter trunk, root length, root volume, fresh weight of plants, plant dry weight, fruit weight and number of fruit), and the addition of NPK nutrition significantly affect variable leaf number, branch number, and fresh weight of plants.</em></p><p> </p></div>
IMPLEMENTASI SISTEM PAKAR UNTUK MENDIAGNOSIS PENYAKIT DENGAN GEJALA DEMAM MENGGUNAKAN METODE CERTAINTY FACTOR
Authors: Daniel Daniel , Virginia Gloria 
Published: March 2018

Sistem pakar untuk diagnosis penyakit dibangun dengan menerapkan metode certainty factor. Sistem tersebut memberikan hasil berupa kemungkinan penyakit yang dialami, prosentase keyakinan, serta solusi pengobatan berdasarkan fakta-fakta dan nilai keyakinan yang diberikan oleh pengguna dalam menjawab pertanyaan selama sesi konsultasi ketika menggunakan sistem ini. Implementasi sistem ini digunakan untuk mengevaluasi proses akuisisi pengetahuan dalam membangun basis pengetahuan.