bluuebunny/crossref_metadata_2025_split huggingface dataset:
DAYA HAMBAT EKSTRAK ETANOL Schismatoglottis sp. TERHADAP BAKTERI Staphylococcus aureus dan Escherichia coli
Authors: Bian Fahri , Kandou Febby E.F. , Rumondor Marhaenus J. 
Published: July 2019

DAYA HAMBAT EKSTRAK ETANOL Schismatoglottis sp. TERHADAP BAKTERI Staphylococcus aureus dan Escherichia coliABSTRAK Penelitian ini bertujuan untuk mengetahui daya hambat ekstrak etanol daun Schismatoglottis sp. terhadap bakteri Staphylococcus aureus dan Escherichia coli. Daya hambat ekstrak etanol Schismatoglottis sp. terhadap bakteri menggunakan metode Kirby-Bauer, yaitu metode difusi dengan cakram kertas. Ekstrak etanol Schismatoglottis sp. menghambat pertumbuhan S. aureus pada konsentrasi 60% dan 90% dengan diameter zona hambat 16,10 mm dan 31,33 mm serta terhadap E. coli pada konsentrasi 30%, 60%, dan 90% dengan diameter zona hambat berturut-turut 11,72 mm, 16,38 mm, dan 29,27 mm. Berdasarkan hasil penelitian, dapat disimpulkan bahwa ekstrak etanol Schismatoglottis sp. terhadap S. aureus pada konsentrasi 60% dan 90% masing-masing memiliki kekautan antibakteri termasuk kategori kuat dan sangat kuat, sedangkan terhadap E. coli pada konsentrasi 30% dan 60%, memiliki kekuatan antibakteri kategoti kuat sedangkan pada konsentrasi 90% memiliki kekuatan antibakteri kategori sangat kuat. Kata kunci : Schismatoglottis sp, Antibakteri, Staphylococcus aureus, Escherichia coli THE INHIBITION OF ETHANOL EXTRACT OF Schismatoglottis sp. AGAINST BACTERIA Staphylococcus aureus AND Escherichia coli. ABSTRACT This study aimed to determine the inhibition of ethanol extract of leaves Schismatoglottis sp. against S. aureus and E. coli. Inhibition of the ethanol extract of Schismatoglottis sp. against to bacterial using the Kirby-Bauer method, is the paper disk diffusion method. Schismatoglottis sp. ethanol extract inhibit the growth of S. aureus at a concentration of 60% and 90% inhibition zone with a diameter of 16.10 mm and 31.33 mm and against E. coli at a concentration of 30%, 60%, and 90% with inhibition zone diameter respectively 11, 72 mm, 16.38 mm and 29.27 mm. Based on the results, it can be concluded that the ethanol extract Schismatoglottis sp. against S. aureus at concentrations of 60% and 90% respectively have antibacterial kekautan categorized as strong and very strong, while against E. coli at a concentration of 30% and 60%, have a strong kategoti antibacterial strength while at a concentration of 90% has antibacterial strength very strong category. Keywords: Schismatoglottis sp, antibacterials, Staphylococcus aureus, Escherichia coli.
INTERAKSI ANTARA MIKROBIOTA USUS DAN SISTEM KEKEBALAN TUBUH MANUSIA
Authors: Hasibuan Fitri Elizabrth Br , Kolondam Beivy Jonathan 
Published: July 2019

INTERAKSI ANTARA MIKROBIOTA USUS DAN SISTEM KEKEBALAN TUBUH MANUSIA Fitri Elizabrth Br Hasibuan dan Beivy Jonathan Kolondam ABSTRAK Sejumlah besar mikrobiota yang menghuni sistem pencernaan manusia memiliki peran penting dengan sistem kekebalan tubuh. Mikrobiota ini melaksanakan fungsi penting untuk fisiologi inang. Dalam tubuh manusia terdapat sekitar 10-100 triliun mikrobiota. Jumlah mikrobioma pada manusia paling banyak terdapat di usus, yaitu sekitar 100 triliun sel-sel mikrobiota yang terdiri dari 1.000 spesies berbeda. Mikrobiota adalah seluruh mikroba yang hidup di tubuh manusia yang terdiri dari bakteri, archae, virus, dan jamur yang pada umumnya hidup di setiap bagian tubuh manusia seperi kulit, vagina, hidung dan mulut. Bakteri pada mikrobioma manusia memiliki peran pada imunitas, nutrisi, dan perkembangan manusia. Di sini ditinjau tentang interaksi antara koloni mikroba dan sistem kekebalan tubuh dan implikasi dari temuan ini bagi kesehatan manusia. Kata-kata kunci: mikrobiota usus, sistem kekebalan tubuh, interaksi, bakteria. INTERACTION BETWEEN GUT MICROBIOTA AND THE HUMAN IMMUNE SYSTEM ABSTRACT Most of the gut microbiota has important role in human immune system. These microbiota conducts important function for host physiology. The microbiota in the human body can range around 10 to 100 billion in number which contained 1,000 different species. Microbiota are the whole microbes living in human body such as bacteria, archaea, virus, and fungi, located on the skin or inside the vagina, nose and mouth. Bacteria in human microbiome has important roles in nutrition, immunity, and human development. This article discussed about interaction of microbes and immune system along with the implication of the interaction for human health. Keywords: Gut microbiota, immune system, interaction, bacteria
ANALISIS PENGENDALIAN PERSEDIAAN BAHAN BAKU BUNGA KRANS PADA USAHA BUNGA PLASTIK DENGAN MENGGUNAKAN METODE ECONOMIC ORDER QUANTITY DAN METODE ECONOMIC PRODUCTION QUANTITY
Authors: Tipaka Yulin , Paendong Marline , Mongi Charles 
Published: July 2019

ANALISIS PENGENDALIAN PERSEDIAAN BAHAN BAKU BUNGA KRANS PADA USAHA BUNGA PLASTIK DENGAN MENGGUNAKAN METODE ECONOMIC ORDER QUANTITY DAN METODE ECONOMIC PRODUCTION QUANTITYABSTRAK Bunga Krans merupakan suatu karangan bunga berbentuk lonjong dan sebagainya untuk ucapan duka cita. Dalam usaha ini tidak sedikit permasalahan tentang meminimumkan biaya dengan mengendalikan prersediaan bahan baku. Tujuan penelitian ini yaitu untuk menentukan jumlah pemesanan ekonomis menggunakan metode Economic Order Quantity (EOQ) dan produksi optimal menggunakan metode Economic Produciton Quantity (EPQ) serta menentukan total persediaan minimum menurut EOQ dan EPQ. Dimana penelitian ini dilakukan pada bulan Februari 2017 hingga April 2017 di perusahaan Kembang Lineke, Girian, Bitung. Dengan variabel yang digunakan yaitu volume kebutuhan bahan baku, volume penyaluran bahan baku, biaya pemesanan bahan baku dan biaya penyimpanan bahan baku. Dari hasil dapat diketahui bahwa pemesanan ekonomis menurut metode EOQ untuk masing-masing jenis bunga K5, K6 dan K10 yaitu 205,88 lusin, 220,09 lusin dan 266,96 lusin dengan biaya optimal semua jenis bunga sebesar Rp. 125.476.400 sedangkan produksi optimal menurut metode EPQ untuk jenis bunga K5, K6 dan K10 masing-masing sebesar 206,16 lusin, 220,4 lusin dan 267,32 lusin dengan biaya optimal untuk semua jenis bunga sebesar Rp. 125.336.630. Kata Kunci: Bunga Krans, Economic Order Quantity (EOQ), Economic Production Quantity (EPQ) RAW MATERIAL INVENTORY CONTROL ANALYSIS OF FUNERAL WREATH ON PLASTIC FLOWER BUSINESS USING ECONOMIC ORDER QUANTITY METHOD AND ECONOMIC PRODUCTION QUANTITY METHODABSTRACT Funeral wreath is an oval-shaped bouquet or so on used for show greeting or grieving. In this business there are not only a few problems about minimizing costs by controlling raw material inventory. The purpose of this research is to determine the amount of economic order using Economic Order Quantity (EOQ) method and optimum production using Economic Production Quantity (EPQ) method, also to determine the total minimum inventory according to those methods. Where this research was conducted in February 2017 until April 2017 at company Flower Lineke, Girian, Bitung. With variables used are the volume of raw material demand, the volume of raw material distribution, ordering cost and holding cost. From the results it can be seen that economical order according to EOQ method for each type of interest K5, K6 and K10 is 205,88 dozen, 220,09 dozen and 266,96 dozen with optimal cost of all type of interest equal to rp.125,476,400 while the optimum production according to EPQ method for k5, k6, k10, respectively for 206,16 dozen 220,4 dozen and 267,32 dozen with optimal cost for all kinds of interest Rp. 125.336.630. Keywords: Funeral Wreath, Economic Order Quantity (EOQ), Economic Production Quantity (EPQ)
KANDUNGAN SERAT KASAR DARI BAKASANG IKAN TUNA (Thunnus sp.) PADA BERBAGAI KADAR GARAM, SUHU DAN WAKTU FERMENTASI
Authors: Korompot Abdul R.H. , Fatimah Feti , Wuntu Audy D. 
Published: July 2019

KANDUNGAN SERAT KASAR DARI BAKASANG IKAN TUNA (Thunnus sp.) PADA BERBAGAI KADAR GARAM, SUHU DAN WAKTU FERMENTASI ABSTRAKBakasang ikan tuna adalah salah satu produk fermentasi yang umumnya dibuat dari jeroan ikan tuna dengan penambahan garam. Oleh karena itu, dilakukan penelitian dengan tujuan Mengetahui kandungan serat kasar dari bakasang ikan tuna (Thunnus sp.) pada berbagai kondisi pengolahan. Kajian yang dilakukan meliputi pengujian analisis kadar serat kasar. Penelitian telah dilaksanakan bulan Januari sampai Maret di Laboratorium Biokimia Universitas Sam Ratulangi dan Laboratorium Badan Riset dan Standarisasi Industri Manado. Hasil terbaik kadar serat kasar bakasang ikan tuna dengan kadar garam terbaik kadar garam 30%, suhu 50oC dan waktu fermentasi 15 hari yaitu 1,0018% yang menunjukan kandungan gizi yang baik untuk kesehatan.Kata kunci : Ikan Tuna (Thunnus sp.), Gizi, Bakasang, Serat Kasar THE RIGHT FIBER CONTENT OF THE TUNA FISH BAKASANG (Thunnus sp.) ON VARIOUS CONDITIONS OF SALT, TEMPERATUREAND FERMENTATION TIMEABSTRACT Bakasang tuna is one of the fermentation products that are generally made from tuna innards by detailing the salt. Therefore, research is conducted with the aim of containing crude fiber content from tuna tuna (Thunnus sp.) In various processing conditions. The study included the testing of crude fiber content. The research has been conducted from January to March in the Biochemical Laboratory of Sam Ratulangi University and Laboratory of Manado Industry Research and Standards Agency. The best results of crude fiber content of tuna fish with salt content of 30% salt, 50oC temperature and fermentation time of 15 days is 1.0018% indicating good nutrition for health.Keyword: Tuna (Thunnus sp.), Nutrition, Bakasang, Rough Fiber
KELIMPAHAN DAN KEANEKARAGAMAN MAKROZOOBENTOS DI SUNGAI AIR TERJUN TUNAN, TALAWAAN, MINAHASA UTARA, SULAWESI UTARA
Authors: Pelealu Grasideo V.E. , Koneri Roni , Butarbutar Regina Rosita 
Published: July 2019

KELIMPAHAN DAN KEANEKARAGAMAN MAKROZOOBENTOS DI SUNGAI AIR TERJUN TUNAN, TALAWAAN, MINAHASA UTARA, SULAWESI UTARAABSTRAKMakrozoobentos merupakan organisme akuatik yang hidup di dasar perairan dengan pergerakan relatif lambat yang sangat dipengaruhi oleh substrat dasar serta kualitas perairan. Penelitian ini bertujuan untuk menganalisis keanekaragaman makrozoobentos yang terdapat di sungai air terjun Tunan, Desa Talawaan, Minahasa Utara, Sulawesi Utara. Pengambilan sampel dilakukan pada tiga stasiun. Stasiun 1 (Air Terjun Tunan), Stasiun 2 (Pintu masuk wisata), dan Stasiun 3 (Perkebunan). Pengambilan sampel makrozoobentos menggunakan metode purposive random sampling. Pengambilan sampel makrozoobentos di dasar perairan dengan menggunakan jaring surber yang berukuran ukuran 25 cm x 40 cm. Hasil penelitian menunjukan makrozoobentos yang ditemukan di sungai air terjun Tunan terdiri dari 3 filum, 3 kelas, 10 bangsa, 20 suku, dan 23 marga serta 379 individu. Marga makrozoobentos yang sering di jumpai yaitu Hydropsyche dan Suku makrozoobentos yang paling sering dijumpai yaitu suku Heptageniidae. Indeks keanekaragaman makrozoobentos tertinggi pada stasiun 1 (2,69), kemudian diikuti oleh stasiun 2 (2,31) dan terendah pada stasiun 3 (1,94).Kata kunci: Air terjun Tunan, Indeks Keanekaragaman, Makrozoobentos ABUNDANCE AND DIVERSITY OF MACROZOOBENTOS IN TUNAN WATERFALL RIVER, TALAWAAN, NORTH MINAHASA, NORTH SULAWESI ABSTRACTMacrozoobenthos are aquatic organisms that live at the bottom of the waters with relatively slow movements that are strongly influenced by the basic substrate and the quality of the waters. This study aims to analyze the diversity of macrozoobenthos in the Tunan waterfall river, Talawaan Village, North Minahasa, North Sulawesi. Sampling was carried out at three stations. Station 1 (Tunan Waterfall), Station 2 (tourist entrance), and Station 3 (Plantation). Macrozoobenthos samples were taken using purposive random sampling method. Taking macrozoobenthos samples at the bottom of the water using a surber net measuring 25 cm x 40 cm. The results showed that macrozoobenthos found in the Tunan waterfall river consist of 3 phylum, 3 classes, 10 ordo, 20 familia, and 23 genus and 379 individuals. Macrozoobenthic genus that are often encountered are Hydropsyche and the most common macrozoobenthic classis, the Heptageniidae classis. The highest macrozoobenthos diversity index at station 1 (2.69), followed by station 2 (2.31) and the lowest at station 3 (1.94). Keywords: Tunan Waterfall, Diversity Index, Macrozoobentos
Evolution of Magnetic Helicity in Solar Cycle 24
Authors: Pipin Valery V. , Pevtsov Alexei A. , Liu Yang , Kosovichev Alexander G. 
Published: July 2019

Abstract
We propose a novel approach to reconstruct the surface magnetic helicity density on the Sun or Sun-like stars. The magnetic vector potential is determined via decomposition of vector magnetic-field measurements into toroidal and poloidal components. The method is verified using data from a non-axisymmetric dynamo model. We apply the method to vector field synoptic maps from the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory to study the evolution of the magnetic helicity density during solar cycle 24. It is found that the mean helicity density of the non-axisymmetric magnetic field of the Sun evolves in a way similar to that reported for the current helicity density of the solar active regions. It predominantly has a negative sign in the northern hemisphere, while it is mainly positive in the southern hemisphere. Also, the hemispheric helicity rule for the non-axisymmetric magnetic field showed the sign inversion at the end of cycle 24. The evolution of the magnetic helicity density of a large-scale axisymmetric magnetic field is different from what is predicted by dynamo theory. On one hand, the mean large- and small-scale components of magnetic helicity density display the hemispheric helicity rule of opposite signs at the beginning of cycle 24. However, later in the cycle, the two helicities exhibit the same sign, in contrast with theoretical expectations.
Active Galactic Nuclei in Dusty Starbursts at z = 2: Feedback Still to Kick in
Authors: Rodighiero G. , Enia A. , Delvecchio I. , Lapi A. , Magdis G. E. , Rujopakarn W. , Mancini C. , Rodríguez-Muñoz L. , Carraro R. , Iani E. , Negrello M. , Franceschini A. , Renzini A. , Gruppioni C. , Perna M. , Baronchelli I. , Puglisi A. , Cassata P. , Daddi E. , Morselli L. , Silverman J. 
Published: July 2019

Abstract
We investigate a sample of 152 dusty sources at 1.5 < z < 2.5 to understand the connection of enhanced star formation rate (SFR) and black hole accretion rate. The sources are Herschel-selected, having stellar masses M
* > 1010
M
⊙ and SFR (∼100–1000 M
⊙ yr−1) elevated (>4×) above the star-forming “main sequence,” classifying them as starbursts (SBs). Through a multiwavelength fitting approach (including a dusty torus component), we divided the sample into active SBs (dominated by an active galactic nucleus (AGN) emission, SBs-AGN, ∼23% of the sample) and purely star-forming SBs (SBs-SFR). We visually inspected their Hubble Space Telescope/ultraviolet (UV) rest frame maps: SBs-SFR are generally irregular and composite systems; ∼50% of SBs-AGN are instead dominated by regular compact morphologies. We then found archival Atacama Large Millimeter/submillimeter Array continuum counterparts for 33 galaxies (12 SBs-AGN and 21 SBs-SFR). For these sources we computed dust masses, and, with standard assumptions, we also guessed total molecular gas masses. SBs turn into gas-rich systems (f
gas = M
gas/(M
gas + M
*) ≃ 20%–70%), and the gas fractions of the two SB classes are very similar (f
gas = 43% ± 4% and f
gas = 42% ± 2%). Our results show that SBs are consistent with a mixture of: (1) highly star-forming merging systems (dominating the SBs-SFR) and (2) primordial galaxies, rapidly growing their M
* together with their black hole (mainly the more compact SBs-AGN). Feedback effects have not yet reduced their f
gas. Indeed, SBs at z = 2, with relatively low bolometric AGN luminosities in the range 1044 < L
bol(AGN) < 1046 erg s−1 (compared to bright optical and X-ray quasars), are still relatively far from the epoch when the AGN feedback will quench the SFR in the host and will substantially depress the gas fractions.
A First Search for Prompt Radio Emission from a Gravitational-wave Event
Authors: Callister Thomas A. , Anderson Marin M. , Hallinan Gregg , D’addario Larry R. , Dowell Jayce , Kassim Namir E. , W. Lazio T. Joseph , Price Danny C. , Schinzel Frank K. 
Published: July 2019

Abstract
Multimessenger observations of the binary neutron star merger GW170817 have enabled the discovery of a diverse array of electromagnetic counterparts to compact binary mergers, including an unambiguous kilonova, a short gamma-ray burst, and a late-time radio jet. Beyond these counterparts, compact binary mergers are additionally predicted to be accompanied by prompt low-frequency radio emission. The successful observation of a prompt radio counterpart would be immensely valuable, but is made difficult by the short delay between the gravitational-wave and prompt electromagnetic signals, as well as by the poor localization of gravitational-wave sources. Here, we present the first search for prompt radio emission accompanying a gravitational-wave event, targeting the binary black hole merger GW170104 detected by the Advanced Laser Interferometer Gravitational-Wave Observatory (LIGO) and Virgo during their second (O2) observing run. Using the Owens Valley Radio Observatory Long Wavelength Array, we search a ∼900 deg2 region for transient radio emission within approximately one hour of GW170104, obtaining an upper limit of 2.5 × 1041 erg s−1 on its equivalent isotropic luminosity between 27 and 84 MHz. We additionally discuss plans to target binary neutron star mergers in Advanced LIGO and Virgo’s upcoming O3 observing run.
Procédés cycliques dans la musique de chambre de Joaquín Turina : l’exemple des Quintette op. 1 et Sextuor avec piano op. 7
Authors: Etcharry Stéphan 
Published: July 2019

Entre 1905 et 1913, le jeune Sévillan Joaquín Turina décide de venir se perfectionner à Paris en suivant notamment les cours de composition d’Auguste Sérieyx et de Vincent d’Indy à la Schola Cantorum. La « forme cyclique » représente dans sa musique l’un des traits stylistiques directement hérités de la pédagogie scholiste de ce tout premier xx e siècle. Le corpus de musique de chambre choisi permet d’étudier la manière dont évolue l’attitude du compositeur face au traitement du procédé cyclique. En effet, si l’opus 1 de 1907 s’engouffre aveuglément dans la brèche de la pensée de la Schola, mettant en application les préceptes professés par Sérieyx et d’Indy, l’opus 7 de 1912 témoigne en revanche d’un premier stade de décantation du langage qui s’accompagne notamment d’une pénétration plus affirmée de la couleur et du paysage andalou, dans un geste quasi impressionniste.
Votre enfant chante à l’école ?… Eh bien, dansons maintenant !
Authors: Berlioz-Ruffiot Anne 
Published: July 2019

En tant qu’enseignante spécialisée, je suis sollicitée par les enseignants d’écoles maternelles et élémentaires, pour les enfants en difficultés scolaires ou comportementales (manque de concentration, de cadre, d’autonomie, de confiance en eux, agressivité, etc.) avec le mandat institutionnel d’impliquer les familles. Quelle lecture opérationnelle choisir de la situation ? Comment entraîner enfant et parents, qui ne sont pas à l’origine de la demande, dans cette fameuse « danse » susceptible de conduire au changement ? Quel type de danse leur proposer ? J’exposerai les grandes lignes de ma démarche avant de proposer une rapide classification du type d’outils ou « pas de danse » que j’utilise.
Les jeunes au cœur de la « coparentalité satisfaisante » après la séparation parentale
Authors: Stolnicu Alexandra , Hendrick Stéphan 
Published: July 2019

L’objectif de notre étude est d’enrichir la compréhension du concept de coparentalité « satisfaisante » post-rupture conjugale. En essayant de répondre à la question suivante : Comment les adolescents vivent la qualité de la relation coparentale de leurs parents après la séparation conjugale ? Nous avons analysé le vécu de cinq jeunes issus de deux couples parentaux hétérosexuels séparés. L’analyse phénoménologique interprétative – IPA (Smith et coll., 2009) nous a permis de dégager deux thèmes principaux qui semblent décrire la manière dont les adolescents vivent la qualité de la relation coparentale de leurs parents après la séparation conjugale : le vécu de la dynamique familiale et la satisfaction de leurs besoins spécifiques.
An integrated model for process parameter adjustment to recover throughput shortage in semiconductor assembly: A case study
Authors: Kok Hoe Ho , Prakash Joshua , Kamaruddin Shahrul , Kok Seng Ong 
Published: July 2019

Purpose: Existing productivity improvements activities such as inventory buffer, overall equipment effectiveness (OEE) and total productive maintenance (TPM) do not analytically associate the throughput shortage with process parameters. The paper aims to develop and test an integrated model to recover the throughput shortage through process parameters adjustment in a semiconductor assembly.Design/methodology/approach: The mathematical model of planned throughput is developed as a function of input parameters in an integrated multiple process line. When the planned throughput does not meet the real-time throughput, the throughput shortage occurs. The planned throughput for the next day is summed with the throughput shortage from previous day and mathematical programming is used to find the optimum process parameter values. Findings: The throughput shortage is restored using mathematical programming for the subsequent day of planning. If there still exist throughput shortage, the additional throughput shortage will be carried forward for the subsequent day of planning where mathematical programming is used again to find the adjusted process parameters. The proposed optimization model in essentially a parametric model using input parameters of real-time data based on a normal distribution that is translated into a range of minimum and maximum using 95% confidence interval.Research limitations/implications: The adjusted input parameters in this model is based on the cycle time of three processes which are Die Attach, Wire Bond and Pre-Cap Inspection. Downtime and setup time are not subjected to adjustments.Practical implications: The mathematical programming computes optimum process parameters values to restore the throughput shortage where it correlates the process parameters and throughput shortage quantitatively rather than conventional method of throughput shortage recovery.Originality/value: The research addresses the process parameter adjustment to recover the throughput shortage in integrated multiple processes.
Identification of the E3 Ligase TRIM29 as a Critical Checkpoint Regulator of NK Cell Functions
Authors: Dou Yaling , Xing Junji , Kong Gangcheng , Wang Guangchuan , Lou Xiaohua , Xiao Xiang , Vivier Eric , Li Xian C. , Zhang Zhiqiang 
Published: July 2019

Abstract
NK cells play an important role in immune surveillance and protective immunity, mainly through rapid cytokine release and cytolytic activities. But how such responses are negatively regulated remains poorly defined. In this study, we demonstrated that the E3 ubiquitin ligase TRIM29 is a crucial regulator of NK cell functions. We found that TRIM29 was not expressed in resting NK cells, but was readily upregulated following activation, especially after IL-12 plus IL-18 stimulation. The levels of TRIM29 expression were inversely correlated with IFN-γ production by NK cells, suggesting that TRIM29 inhibits NK cell functions. Indeed, deficiency of TRIM29, specifically in NK cells, resulted in an enhanced IFN-γ production and consequently protected mice from murine CMV infection. Mechanistically, we showed that once induced in NK cells, TRIM29 ubiquitinates and degrades the TGF-β–activated kinase 1 binding protein 2 (TAB2), a key adaptor protein in IFN-γ production by NK cells. These results identify TRIM29 as a negative regulator of NK cell functions and may have important clinical implications.