bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the R CrA environment with SPHERE
Authors: Mesa D. , Bonnefoy M. , Gratton R. , Van Der Plas G. , D’Orazi V. , Sissa E. , Zurlo A. , Rigliaco E. , Schmidt T. , Langlois M. , Vigan A. , Ubeira Gabellini M. G. , Desidera S. , Antoniucci S. , Barbieri M. , Benisty M. , Boccaletti A. , Claudi R. , Fedele D. , Gasparri D. , Henning T. , Kasper M. , Lagrange A.-M. , Lazzoni C. , Lodato G. , Maire A.-L. , Manara C. F. , Meyer M. , Reggiani M. , Samland M. , Van den Ancker M. , Chauvin G. , Cheetham A. , Feldt M. , Hugot E. , Janson M. , Ligi R. , Möller-Nilsson O. , Petit C. , Rickman E. L. , Rigal F. , Wildi F. 
Published: February 2019

Aims. R Coronae Australis (R CrA) is the brightest star of the Coronet nebula of the Corona Australis (CrA) star forming region. This star is very red in color, probably due to dust absorption, and is strongly variable. High-contrast instruments allow for an unprecedented direct exploration of the immediate circumstellar environment of this star.
Methods. We observed R CrA with the near-infrared (NIR) channels (IFS and IRDIS) of SPHERE at the Very Large Telescope (VLT). In this paper, we used four different epochs, three of which are from open time observations while one is from SPHERE guaranteed time. The data were reduced using the data reduction and handling pipeline and the SPHERE Data Center. We implemented custom IDL routines on the reduced data with the aim to subtract the speckle halo. We have also obtained pupil-tracking H-band (1.45−1.85 μm) observations with the VLT/SINFONI NIR medium-resolution (R ∼ 3000) spectrograph.
Results. A companion was found at a separation of 0.156″ from the star in the first epoch and increasing to 0.184″ in the final epoch. Furthermore, several extended structures were found around the star, the most noteworthy of which is a very bright jet-like structure northeast from the star. The astrometric measurements of the companion in the four epochs confirm that it is gravitationally bound to the star. The SPHERE photometry and SINFONI spectrum, once corrected for extinction, point toward a spectral type object that is early M with a mass between 0.3 and 0.55 M⊙. The astrometric analyis provides constraints on the orbit paramenters: e ∼ 0.4, semimajor axis at 27–28 au, inclination of ∼70°, and a period larger than 30 yr. We were also able to put constraints of few MJup on the mass of possible other companions down to separations of few tens of au.
Prä- und postoperatives Vorgehen bei der primären
Endoprothetik am Kniegelenk
Authors: Matziolis Georg , Röhner Eric 
Published: February 2019

ZusammenfassungNicht alle der Patienten, die mit einer Knieendoprothese versorgt werden, sind
mit dieser komplett zufrieden im Sinne eines „Forgotten Knee“. Die stetige
Verbesserung der Operationstechnik und Nachbehandlung sowie die Verringerung von
Komplikationen stehen daher weiterhin im Fokus der Endoprothetik. Die Autoren
geben hierzu einen umfassenden Überblick.
Endoprothesen des Kniegelenks – ein Überblick für
Manualtherapeuten
Authors: Ranker Alexander , Steinbrück Arnd 
Published: February 2019

ZusammenfassungDie Anzahl der Erstimplantationen einer Knieendoprothese stieg in den letzten
Jahren stetig an. Und auch die Erwartungen der Patienten an eine Prothese sind
gestiegen: Das künstliche Gelenk sollte nach einer gewissen Zeit im besten Fall
nicht mehr als solches wahrgenommen werden. Eine adäquate postoperative
Therapie, in der die Manuelle Therapie ein wichtiger Baustein ist, trägt dazu
bei, dass der Zustand des „Forgotten Knee“ erreicht werden kann. Ein
grundlegendes Wissen über die unterschiedlichen Knieendoprothesen kann dabei
unterstützen, postoperative Funktionsdefizite besser zu verstehen und die
bestmögliche Therapie anzubieten.
Thoracoscopic Diagnosis of Follicular Lymphoma Relapsing after 13 Years
Authors: Kanbur Serda , Derdiyok Onur , Kiral Hakan , Yilmaz Hakan , Demir Mine , Tezel Cagatay , Baysungur Volkan , Evman Serdar 
Published: February 2019

AbstractRelapse in lymphoproliferative malignancies is not an exceptional entity and generally occurs within the first 2 or 3 years following the primary treatment. Lymph node biopsy is essential for the diagnosis of relapse and treatment. A 64-years-old woman was referred to our clinic for back pain and dyspnea. Chest X-ray and computed tomography (CT) showed pleural thickening in the right hemithorax and pleural effusion. Hereby, we report a patient with a history of follicular lymphoma treatment 13 years ago, presenting with unilateral pleural effusion and being diagnosed, unpredictably, with relapsing lymphoma by video-assisted thoracoscopic surgery pleural biopsy.
Bilateral Simultaneous Endoscopic Dacryocystorhinostomy: Outcome and Impact on the Quality of Life of the Patients
Authors: Herzallah Islam R. , Marglani Osama A. , Alherabi Ameen Z. , Faraj Nuha S. , Bukhari Deemah H. 
Published: February 2019

Introduction Bilateral simultaneous endoscopic dacryocystorhinostomy (endo-DCR) has received little attention in the literature, thus many surgeons continue to address bilateral nasolacrimal duct obstruction at two stages, rather than in the same setting.
Objective To evaluate the feasibility and the outcome of simultaneous bilateral Endo-DCR and its impact on the quality of life of the patients.
Methods We have conducted a retrospective analysis of patients who underwent bilateral simultaneous endo-DCR between March 2013 and February 2017 at our tertiary care institution. The reviewed data included clinical presentation; operative details; success rate; pre and postoperative evaluation of the symptoms of the patients, using the Nasolacrimal Duct Obstruction Symptom Score Questionnaire; satisfaction of the patients, and improvement in the quality of life, assessed by the Glasgow Benefit Inventory (GBI) questionnaire.
Results Out of 128 cases in which endo-DCRs were performed, 13 were bilateral (26 sides). Postoperative success was documented in 24 of the 26 sides (92.3%), with a mean follow-up duration of 16.2 months. The two failed sides were reported in the same case. The preoperative symptom score ranged between 12 and 80 (mean ± standard deviation [SD]: 38.23 ± 15.7). The postoperative symptom score was significantly lower (mean ± SD: 5.4 ± 12.9). The success rates in unilateral and bilateral cases were comparable, with no statistically significant difference. A notable improvement in the quality of life of the patients was also reported, with a mean GBI score of 81.38 ± 12.37.
Conclusion Our results support that a simultaneous bilateral endo-DCR is a safe procedure that offers a high success rate, spares the patient from the stress of a second surgery, provides the patient with a bilateral resolution of the symptoms, and confers an immediate improvement in the quality of life of the patients.
Metastatic Disease, Myeloma, and Lymphoma Affecting the Hip
Authors: Gianakos Arianna , Patel Jay , Miller Justin , Sonnylal Laura , Wittig James 
Published: February 2019

AbstractThe three most common causes for bony lesions in patients over 40 years of age are metastatic disease, multiple myeloma, and lymphoma. Oftentimes, these conditions have a predilection for the hip region. The authors present the incidence, characteristics, and treatment of metastatic disease, multiple myeloma, and lymphoma affecting the hip joint to help clinicians accurately diagnose and manage these conditions. They also present the senior author's technique of cemented long stem hemiarthroplasty for treating these conditions when they affect the proximal femur.
Polentone vs terrone
Authors: Viola Lorella 
Published: February 2019

Abstract
This article explores how the internal conflict between the Italian Northern and Southern regions’ ideologies is linguistically apparent in the use of the discriminating words polentone (literally, polenta eater) attached to people from the North and terrone (literally, person from the land) referred to people from the South. The research hypothesis is that, although at first these terms appear to carry a similar derogatory connotation, terrone is in fact more offensive. It is argued here that such difference may find its roots in the Italian central government political strategies which, by historically favouring one part of the country to the disadvantage of the other, have factually aggravated the production and reproduction of discriminatory prejudices against the South. By using the “discourse-historical approach” (Wodak 2001), the study triangulates linguistic, social and historical data to unveil correlations between the discursive discrimination against Italian intra-migrants and the implicit ideologies circulated by governmental choices.
Practical reasoning and metaphor in TV discussions on immigration in Greece
Authors: Butulussi Eleni 
Published: February 2019

Abstract
This article investigates the dynamic processes taking place in relation to the choice of specific fixed metaphors which function as framing devices by rival politicians to reinforce their proposals for action in the media immigration discourse of Greek TV discussions (1996-2016). In this research context a critical, integrated, multi-level metaphor analysis model is suggested which combines different methods (see Cameron 2008; Fairclough et al. 2012; Charteris-Black 2014; Musolff 2016; Semino et al. 2016) for a linguistic, cognitive and discursive-communicative-rhetorical analysis in the context of practical reasoning focusing on the framing power of metaphor. Results revealed that around these metaphors the different political ideologies are framed in agreement with the rhetorical tendencies (e.g simplification, bipolarization, hyperbole) of the political media discourse.
Grammatical relations in Movima
Authors: Haude Katharina 
Published: February 2019

Movima (isolate, Bolivia) has two transitive constructions: direct/ergative and inverse/accusative. The most straightforward argument selector is relativization. Relativization selects the P of the direct and the A of the inverse construction, which, in each case, is the argument whose referent ranks lower on scales of person, animacy, and topicality. In terms of constituency, this is the “external” argument, and it aligns with S. Certain oblique-marked arguments can be relativized as well, so relativization is a test to distinguish oblique arguments from adjuncts. Other constructions that privilege the external argument are demonstrative fronting and argument incorporation – although the latter is restricted to the direct construction and therefore also to the P argument. Two constructions select an argument on the basis of its semantic role: possessor ascension privileges P, and imperatives, which participate in the direct/inverse alternation, privilege A. Other cross-linguistically typical argument selectors do not seem to show a preference for a particular argument or semantic role: reflexives, coordination, embedding, and quantifier floating.
The Influence of Fluid Management on Outcomes in Preeclampsia: A Systematic Review and Meta-Analysis
Authors: Pretorius T. , van Rensburg G. , Dyer R.A. , Biccard B.M. 
Published: February 2019

(Int J Obstet Anesth. 2018;34:85–95)
One of the leading causes of maternal mortality is complications due to hypertensive disorders of pregnancy. Many guidelines for severe preeclampsia advocate a restrictive approach to fluid management; however, data to support these recommendations are limited. This systematic review and meta-analysis was undertaken to update the evidence regarding the effect of fluid management in preeclampsia on patient outcomes.
Risk-stratification, Resource Availability, and Choice of Surgical Location for the Management of Parturients With Abnormal Placentation: A Survey of United States-based Obstetric Anesthesiologists
Authors: Grant T.R. , Ellinas E.H. , Kula A.O. , Muravyeva M.Y. 
Published: February 2019

(Int J Obstet Anesth. 2018;34:56–66)
Best outcomes are achieved for patients with abnormally adherent placentation when deliveries are well-coordinated with a multidisciplinary team and the ready availability of needed resources is ensured. It is most appropriate for smaller hospitals to transfer patients with suspected abnormal placentation if the institution is unlikely to have the necessary resources to provide optimal care, including sufficient blood supply, subspecialty providers, and other necessary personnel. The objective of this survey was to obtain information from obstetric anesthesiologists in the United States regarding risk-stratification and surgical-location decision-making for parturients with abnormal placentation.
Aspirin for Evidence-based Preeclampsia Prevention Trial: Effect of Aspirin on Length of Stay in the Neonatal Intensive Care Unit
Authors: Wright D. , Rolnik D.L. , Syngelaki A. , de Paco Matallana C. , Machuca M. , de Alvarado M. , Mastrodima S. , Tan M.Y. , Shearing S. , Persico N. , Jani J.C. , Plasencia W. , Papaioannou G. , Molina F.S. , Poon L.C. , Nicolaides K.H. 
Published: February 2019

(Am J Obstet Gynecol. 2018;218:612.e1–e6)
Preeclampsia is a major cause of maternal and perinatal death and other adverse outcomes for mothers and babies, and has important health care cost implications. Previous studies have found a reduction of the risk of preeclampsia with the use of aspirin. This study aimed to examine the effect of aspirin on the length of stay in the neonatal intensive care unit (NICU), as well as evaluate the impact of screening for preeclampsia and aspirin treatment for high-risk patients on health care costs.
The Association of Targeted Cell Salvage Blood Transfusion During Cesarean Delivery With Allogeneic Packed Red Blood Cell Transfusions in a Maternity Hospital in China
Authors: Yan H. , Hu L.Q. , Wu Y. , Fan Q. , Wong C.A. , McCarthy R.J. 
Published: February 2019

(Anesth Analg. 2018;127:706–713)
Allogeneic blood transfusion is an important component in the treatment of postpartum hemorrhage. Short-term risks include acute transfusion reactions, hemolytic anemia, and transfusion-related acute lung injury, whereas long-term risks include immunosuppression. One method to reduce the need for allogeneic packed red blood cell (PRBC) transfusion after cesarean delivery (CD) is to use autologous blood transfusion obtained via intraoperative cell salvage (ICS). Consensus statements suggest that ICS is particularly beneficial in cases of anticipated massive blood loss—>20% or more of the patient’s estimated blood volume. In the current study, the authors assessed allogeneic transfusion rates before and after implementation of a targeted ICS infusion program in women undergoing CD at the Ningbo Women and Children’s Hospital (NWCH) in China.
Determination of the Optimal Programmed Intermittent Epidural Bolus Volume of Bupivacaine 0.0625% With Fentanyl 2 μg/mL at a Fixed Interval of 40 Minutes: A Biased Coin Up-and-down Sequential Allocation Trial
Authors: Zakus P. , Arzola C. , Bittencourt R. , Downey K. , Ye X.Y. , Carvalho J.C. 
Published: February 2019

(Anaesthesia. 2018;73:459–465)
The use of programmed intermittent epidural bolus (PIEB) to provide labor analgesia has been increasing in popularity as commercially available pumps have become available. A variety of dosing strategies have been evaluated but the optimal settings for PIEB have not yet been established. The majority of studies have included PIEB in conjunction with patient controlled epidural analgesia (PCEA). The current investigators had previously investigated which PIEB dosing strategy would minimize breakthrough pain and the need for PCEA boluses. They determined the optimal regimen was 10 mL of bupivacaine 0.0625% with fentanyl 2 µg/ml administered every 40 minutes. However, 34% of women exhibited a sensory block to ice above T6, which might indicate an unnecessarily high spread of local anesthetic. Therefore, they conducted this prospective, double-blind, dose-finding study to investigate whether it was possible to reduce the PIEB volume without compromising the efficacy of the technique.
A Triple-blind, Placebo-controlled Randomized Trial of the Ilioinguinal-transversus Abdominis Plane (I-TAP) Nerve Block for Elective Cesarean Section
Authors: Staker J.J. , Liu D. , Church R. , Carlson D.J. , Panahkhahi M. , Lim A. , LeCong T. 
Published: February 2019

(Anaesthesia. 2018;73:594–602)
Moderate or severe pain after cesarean section has been reported in 7% of women. The ilioinguinal-iliohypogastric block and the transversus abdominis plane (TAP) block have both been effective at reducing postoperative opioid requirements after lower abdominal surgery. However, in studies that compared either of these blocks with spinal morphine, there was no benefit found with the nerve blocks. Regardless, some patients do develop postcesarean pain despite receiving spinal morphine. At the investigators’ institution they began performing a combined ilioinguinal-transversus abdominis plane (I-TAP) nerve block and found it provided improved analgesia. Therefore, this prospective, randomized, placebo-controlled trial was performed to formally evaluate the efficacy of the I-TAP block, hypothesizing that the addition of the block to a multimodal analgesic regimen that included spinal morphine would reduce opioid consumption in the first 24 hours after cesarean section.
Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3
Authors: Moura Marta Casal , Thompson Gwen E. , Nelson Darlene A. , Fussner Lynn A. , Hummel Amber M. , Jenne Dieter E. , Emerling Daniel , Volkmuth Wayne , Fervenza Fernando C. , Kallenberg Cees G.M. , Langford Carol A. , McCune W. Joseph , Merkel Peter A. , Monach Paul A. , Seo Philip , Spiera Robert F. , Clair E. William St. , Ytterberg Steven R. , Stone John H. , Robinson William H. , Pang Yuan-Ping , Specks Ulrich ,   the WGET and RAVE-ITN Research Groups
Published: February 2019

AbstractObjectiveProteinase 3 (PR3) is the major antigen for anti-neutrophil cytoplasmic antibodies (ANCAs) in the systemic autoimmune vasculitis, granulomatosis with polyangiitis (GPA). PR3 anti-neutrophil cytoplasmic antibodies (PR3-ANCAs) recognize different epitopes on PR3. We aimed to study the effect of mutations on PR3 antigenicity.MethodsThe recombinant PR3 variants, iPR3 which is clinically used to detect PR3-ANCAs and iHm5 which contains three point mutations in Epitope 1 and 5 generated for epitope mapping studies, immunoassays and serum samples from patients enrolled in ANCA-associated vasculitis (AAV) clinical trials were used to screen the differential PR3-ANCA binding. Selective binding was determined by inhibition experiments.ResultsRather than a reduced binding of PR3-ANCAs to iHm5, we found substantially increased binding of the majority of PR3-ANCAs to iHm5 compared with iPR3. A monoclonal ANCA (moANCA518) from a patient with GPA was found to selectively bind to iHm5 within the mutation-free Epitope 3 and distant from the point mutations of iHm5 contained in Epitope 1 and 5. Binding of iPR3 to monoclonal antibody MCPR3-2 also induced recognition by moANCA518.ConclusionThe preferential binding of PR3-ANCAs from patients like the selective binding of moANCA518 to iHm5 is conferred by increased antigenicity of Epitope 3 on iHm5. This can also be induced on iPR3 when it is captured by monoclonal antibody MCPR-2. This previously unrecognized characteristic of PR3-ANCA interactions with its target antigen has implications for studying antibody-mediated autoimmune diseases, understanding of variable performance characteristics of immunoassays and design of potential novel treatment approaches.
Impacts of reduced inorganic N:P ratio on three distinct plankton communities in the Humboldt upwelling system
Authors: Spilling Kristian , Camarena-Gómez Maria-Teresa , Lipsewers Tobias , Martinez-Varela Alícia , Díaz-Rosas Francisco , Eronen-Rasimus Eeva , Silva Nelson , von Dassow Peter , Montecino Vivian 
Published: February 2019

AbstractThe ratio of inorganic nitrogen to phosphorus (NP) is projected to decrease in the Eastern Boundary Upwelling Systems (EBUS) due to warming of the surface waters. In an enclosure experiment, we employed two levels of NP ratios (10 and 5) for three distinct plankton communities collected along the coast of central Chile (33°S). The primary effect of the NP treatment was related to different concentrations of NO3, which directly influenced the biomass of phytoplankton. Additionally, low inorganic NP ratio reduced the seston NP and Chla-C ratios, and there were some effects on the plankton community composition, e.g. benefittingSynechococcusspp in some communities. One of the communities was clearly top down controlled and trophic transfer to grazers was up to 5.8% during the 12 day experiment. Overall, the initial plankton community composition was more important for seston stoichiometry and trophic transfer than the inorganic NP ratio. Any long term change in the plankton community structure will likely have greater impact than direct effects of a decreasing inorganic NP ratio on the Humboldt Current ecosystem.
The genome ofAuriculariopsis amplasheds light on fruiting body development and wood-decay of bark-inhabiting fungi
Authors: Almási Éva , Sahu Neha , Krizsán Krisztina , Bálint Balázs , Kovács Gábor M. , Kiss Brigitta , Cseklye Judit , Drula Elodie , Henrissat Bernard , Nagy István , Chovatia Mansi , Adam Catherine , LaButti Kurt , Lipzen Anna , Riley Robert , Grigoriev Igor V. , Nagy László G. 
Published: February 2019

AbstractThe Agaricomycetes are fruiting body forming fungi that produce some of the most efficient enzyme systems to degrade woody plant materials. Despite decades-long interest in the ecological and functional diversity of wood-decay types and in fruiting body development, the evolution of the genetic repertoires of both traits are incompletely known. Here, we sequenced and analyzed the genome ofAuriculariopsis ampla, a close relative of the model speciesSchizophyllum commune. Comparative analyses of wood-decay genes in these and other 29 Agaricomycetes species revealed that the gene family composition ofA. amplaandS. communeare transitional between that of white rot species and less efficient wood-degraders (brown rot, ectomycorrhizal). Rich repertoires of suberinase and tannase genes were found in both species, with tannases generally restricted to species that preferentially colonize bark-covered wood. Analyses of fruiting body transcriptomes in bothA. amplaandS. communehighlighted a high rate of divergence of developmental gene expression. Several genes with conserved developmental expression were found, nevertheless, including 9 new transcription factors as well as small secreted proteins, some of which may serve as fruiting body-specific effector molecules. Taken together, the genome sequence and developmental transcriptome ofAuriculariopsis amplahas highlighted novel aspects of wood-decay diversity and of fruiting body development in mushroom-forming fungi.