bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of a Low-Cost, High-Fidelity Animal Model to Train Graduate Advanced Practice Nursing Students in the Performance of Ultrasound-Guided Central Line Catheter Insertion
Authors: Hauglum Shayne D. , Crenshaw Nichole A. , Gattamorta Karina A. , Mitzova-Vladinov Greta 
Published: October 2018

Introduction
Ultrasound-guided central venous catheter insertion (UGCVC) is a commonly performed procedure taught through simulation. The aims of the study were to examine the utilization of an animal model and compare it with two currently used Blue Phantom central line models to determine whether an animal model provides good or better simulated conditions for the performance of UGCVC insertion.

Methods
Using a randomized cross-over study, 46 advanced practice nursing students were assessed using a task-specific performance tool in their performance of UGCVC insertion on both the animal model and the Blue Phantom models. The number of insertion attempts and time to performance was recorded. A preprocedure survey was used to ascertain their presimulation workshop experience, followed by a postprocedure survey. A cost comparison was completed as a secondary outcome.

Results
A comparison was conducted on the performance scores and the postsurvey results between the animal model and the Blue Phantom models. The number of venous access attempts was not significantly different when comparing the three models. A cost comparison showed the total cost of each animal model was US $15.66 as compared with the approximate cost for the Blue Phantom IJ model of US $1500.00 and the Gen I model of US $2700.00.

Conclusions
Current Blue Phantom models lack the ability to fully perform all the necessary steps critical to the performance of UGCVC insertion. At a total cost of US $15.66 per model, this study showed that training with an alternative economical model was comparable with more expensive mannequin simulators. The results of this study may serve to guide clinicians and educators who are seeking alternative simulation models to provide skill acquisition.
The p.R47H Variant of TREM2 Gene is Associated With Late-onset Alzheimer Disease in Colombian Population
Authors: Arboleda-Bustos Carlos E. , Ortega-Rojas Jenny , Mahecha María F. , Arboleda Gonzalo , Vásquez Rafael , Pardo Rodrigo , Arboleda Humberto 
Published: October 2018

Objective:
We evaluated the association of several single-nucleotide polymorphisms in the triggering receptor expressed on myeloid cells 2 (TREM2) gene in a Colombian sample of late-onset Alzheimer disease (LOAD).

Methods:
The p.Q33* (rs104894002), p.R47H (rs75932628), p.R62H (rs143332484), and p.D87N (rs142232675) variants of TREM2 gene were directly genotyped using KASPar technology in 358 cases and 329 healthy controls. Sanger sequencing was used to validate >10% of KASPar’s results. The Fisher exact test was used to compare the distribution of allelic and genotype frequency between cases and controls, and the Bonferroni correction was set at P<0.05.

Results:
The minor allele frequency of rs75932628-T was 0.009 in cases and was not found in any healthy controls which suggests a significant association between rs75932628-T and LOAD risk in our sample (P=0.010). The rs143332484-T variant did not exhibit a significant association (P=0.160), whereas rs104894002 and rs142232675 were not found.

Conclusions:
Our findings suggest that the rs75932628-T variant of TREM2 is an important risk factor for LOAD in the Colombian population.
Aggregates dramatically alter fibrin ultrastructure
Authors: García X. , Seyve L. , Tellier Z. , Chevreux G. , Bihoreau N. , Polack B. , Caton F. 
Published: October 2018

AbstractAmong the many factors influencing fibrin formation and structure (concentration, temperature, composition, pH,…), it has been suggested that the polydispersity of fibrinogen may play an important role. We propose here a detailed investigation of the influence of this parameter on fibrin multiscale structure.Two commercial fibrinogen preparations were used, a monodisperse and a polydisperse one. First, the respective compositions of both fibrinogen preparations were thoroughly determined by measuring the FXIII, fibronectin, α,β and γ intact-chains contents, theγ/γ’ chains ratio, the N-glycosylation and the post-translational modifications. Slight variations between the composition of the two fibrinogen preparations were found which are much smaller than the compositional variations necessary to alter significantly fibrin multiscale structure as observed in the literature. Conversely, MALLS coupled SEC and DLS measurements showed that the polydisperse preparation contains significant amounts of aggregates while the other preparation is essentially monodisperse.The multiscale structure of the fibrins produced from those two fibrinogen preparations was determined by using X-ray scattering, spectrophotometry, and confocal microscopy. Results show that fibers from the monodisperse fibrinogen present a crystalline longitudinal and lateral structure and form a needle-like network. The internal structure of fibers produced from the polydisperse fibrinogen looks amorphous with star-like branching nodes. The multiscale structure of mixtures between the two preparations shows a smooth evolution, demonstrating that the quantity of aggregates is a major determining factor for fibrin multiscale structure. Indeed, the effect of a few percent in mass of aggregates is larger than any other effect due to compositional differences under the same reaction conditions. Finally we propose a mechanistic interpretation of our results which points at a direct role of the aggregates during polymerization which disrupt the ideal ordering of monomers inside fibrin protofibrils and fibers.
Spring mineral water-borne bacteria reshape gut microbiota profiles and confer health benefits
Authors: Chen YP , Tan LL , Chen DM , Xu Q , Song JP , Zeng QP 
Published: October 2018

BackgroundAlthough dietary patterns are recognized to affect health by interfering with gut microbiota homeostasis, whether live or dead bacteria-bearing spring mineral water (MW) would also exert beneficial effects on health upon curing gut dysbiosis remains unknown.ResultsDue to harboring live bacteria, the heated but unboiled MW from Bama, where centenarians are ubiquitously inhabited, reshapes the gut microbiota from a traveler-type to a local resident-type except for Prevotella. While chondroitin sulfate, a component occurring in livestock and poultry meats, increases the richness of sulfatase-secreting bacteria and sulfate-reducing bacteria, Bama MW dampens the overgrowth of those colon-thinning bacteria and hampers the overexpression of multiple genes responsible for anti-inflammation, anti-oxidation, anti-hypoxia, anti-mutagenesis, and anti-tumorigenesis.ConclusionsBama spring MW prevents the early-phase onset of breast cancer by curating gut dysbiosis. MW also compromises chromosomal DNA damage and ameliorate mitochondrial dysfunctions, implying it may extend lifespan.
Evaluating Kupferstein’s claims of the relationship of behavioral intervention to PTSS for individuals with autism
Authors: Leaf Justin Barrett , Ross Robert K. , Cihon Joseph H. , Weiss Mary Jane 
Published: October 2018

Purpose
Kupferstein (2018) surveyed 460 respondents and found that 46 percent of respondents met the diagnostic threshold for posttraumatic stress disorder after exposure to applied-behavior-analysis-based intervention. The purpose of this paper is to provide an evaluation a critical analysis of Kupferstein (2018) including the experimental methods and discussion of the results.

Design/methodology/approach
The authors evaluated the Kupferstein’s methodological rigor with respect to the use of hypothesis testing, use of indirect measures, selection of respondents, ambiguity in definitions, measurement system, and framing of the experimental question when conducting the correlational analysis in addition to Kupferstein’s analysis and discussion of the results.

Findings
Based upon the analysis, Kupferstein’s results should be viewed with extreme caution due to several methodological and conceptual flaws including, but not limited to, leading questions used within a non-validated survey, failure to confirm diagnosis, and incomplete description of interventions.

Originality/value
It is the authors’ hope that this analysis provides caregivers, clinicians, and service providers with a scientific lens which will useful in viewing the limitations and methodological flaws of Kupferstein.
Publishing research in the international context
Authors: Shehata Ahmed Maher khafaga , Eldakar Metwaly Ali Mohamed 
Published: October 2018

PurposeThe purpose of this paper is to report the findings of a study to explore the Egyptian social science scholars’ academic writing behaviour in local and international context. Understanding the challenges that scholars in social science and humanities face while publishing in the international outlets would help to suggest strategies to improve academic writing in non-Arabic journals.Design/methodology/approachThis study deployed mixed methods approach. The quantitative data were collected using an online questionnaire. Interviews were conducted with a group of scholars in the five faculties to elucidate the publishing behaviour of the sample.FindingsThe interviews and the questionnaire showed that social science scholars in Egypt prefer local publishing outlets. The number of scholars who publish internationally is very low compared to scholars who publish locally. Scholars who tried to publish internationally faced many challenges, such as language barriers, lack of academic writing skills and lack of appropriate training.Research limitations/implicationsThis study was conducted in one university in Egypt. While the results can be generalised to Egyptian and Middle East universities, it cannot be generalised to non-Arab communities because of the differences in culture and education system.Originality/valueThis study provides insight on publishing practices in the international context among social science scholars in Egypt using a mixed methods approach. This helped to capture the scholarly publishing practices and the attitude toward international publishing and the main challenges that scholars face who attempt to publish in international outlets.
MHD stagnation-point flow and heat transfer of a nanofluid over a stretching/shrinking sheet with melting, convective heat transfer and second-order slip
Authors: Pop Ioan , Roşca Natalia C. , Roşca Alin V. 
Published: October 2018

PurposeThe purpose of this paper is to study the effects of MHD, suction, second-order slip and melting on the stagnation-point and heat transfer of a nanofluid past a stretching/shrinking sheet.Design/methodology/approachUsing appropriate variables, the governing partial differential equations were transformed into ordinary (similarity) differential equations, which are then solved numerically using the function bvp4c from Matlab.FindingsIt is found that dual (upper and lower branch) solutions exist for some values of the governing parameters. From the stability analysis, it is found that the upper branch solution is stable, while the lower branch solution is unstable. The sample velocity, temperature and concentration profiles along both solution branches are graphically presented.Originality/valueThe results of the paper are new and original with many practical applications of nanofluids in the modern industry.
Can the offence behaviours of stranger rapists discriminate between UK and non-UK nationals
Authors: Almond Louise , McManus Michelle , Curtis Gemma 
Published: October 2018

Purpose
Currently, no research is available for behavioural investigative advisors’ to provide justifications to infer from the crime scene that an offender is a UK or non-UK national. The paper aims to discuss these issues.

Design/methodology/approach
Data were obtained from National Crime Agency and consisted of 651 stranger rapes, 434 UK nationals and 217 non-UK nationals. All cases were coded for 70 offence behaviour variables. χ2 analyses were conducted to identify significant associations between offence behaviours and offender nationality. Significant associations were then entered into a logistic regression analysis to assess their combined predictive ability of offender nationality.

Findings
Analyses revealed 11 offence behaviours with significant associations to offender nationality: confidence, darkness, offender kisses victim, victim performs sex acts, requests sex acts, apologises, destroys forensics, block entry/exit, weapon – firearm, vaginal penetration – hands/fist/digital, and violence: minimal. From this, seven variables held predictive ability within the logistic regression, with five predicting the non-UK grouping and two the UK grouping.

Research limitations/implications
Future research should test the distinctions between UK and non-UK national stranger rapists and explore the impact of length of residency.

Practical implications
Results indicated that on the whole UK and non-UK stranger rapists display similar behaviours, but there were some distinct behaviours within stranger rape crime scenes, particularly the use of firearms. The ability to use crime scene behaviours to narrow suspect pools by criminal conviction is only useful when police have access to full criminal histories. Unfortunately, the ability to access and search non-UK databases is not always possible. Therefore, this study may be the first step for BIAs to utilise in identifying the likely offender nationality, before using further models that narrow down to criminal history.

Originality/value
This is the first study to examine whether it is possible to differentiate stranger rapists nationality using their offence behaviours.
Teachers’ intergenerational advice and information seeking: content matters!
Authors: Geeraerts Kendra , Vanhoof Jan , Van den Bossche Piet 
Published: October 2018

PurposeThe purpose of this paper is to investigate the role of generation in teachers’ advice and information-seeking interactions in Flemish secondary school teams, and moreover how the content of advice shapes these interactions. Four content-related advice and information-seeking networks are investigated in this study: subject-matter knowledge, classroom management, innovative teaching methods and ICT.Design/methodology/approachData were collected from 660 teachers in ten secondary education schools in Flanders (Belgium) by using an online socio-metric survey. Social network analysis was conducted, more specifically quadratic assignment procedure and multilevel P2 modeling.FindingsThe findings underline the importance of investigating content-related advice networks. Generation affects the formation of interactions. First, the results revealed that older teachers are less likely to ask advice on subject-matter knowledge, classroom management and innovative teaching methods. Second, the data showed that older teachers are more likely to be asked for advice on subject-matter knowledge. Third, young teachers are more likely to be asked for advice on innovative teaching methods and ICT. Fourth, homophily effects occurred for the youngest teachers when advice is about subject-matter knowledge, and for the oldest teachers for advice about classroom management.Originality/valueThis study is innovative due to its application of social network analysis to investigate intergenerational knowledge flows, and due to its clear focus on content-related advice-seeking interactions that go beyond the approach of general advice and information-seeking interactions.
A method to improve the cured bonding strength at the weak juncture of the porous hydrogel scaffold
Authors: Liu Wangyu , Sun Dong , Tang Aimin , Li Mingke 
Published: October 2018

Purpose
Hydrogel is an excellent material for the fabrication of porous scaffold by mask-prototyping method. Different from the common commercial resin, hydrogel is hydrophilic and hyperelastic, so that it cannot bear the conventional post-curing process to improve its mechanical properties. The purpose of this paper is to put forward a method to improve the curing bonding strength at the weak juncture of the porous hydrogel scaffold.

Design/methodology/approach
The working curve of the resin was obtained through the single layer cure experiment, and the energy accumulation model has been set up by MATLAB. Aimed at the specificity of material, a new method of partial curing on different kind of structure has been proposed. Under the same condition, only the tn2 needs to be changed to fabricate different test specimens with different accumulated energy between two layers. The tensile test is carried out with the authors’ preferred equipment.

Findings
The analysis reveals that accumulated energy can be changed by adjusting the key parameters, and the tensile test shows that when the accumulated energy is bigger, the ultimate tensile strength is higher.

Research limitations/implications
Subject to the equipment accuracy and specificity of material, some errors coming from the experiment and test might exist, but the authors believe they will not change their findings and conclusions in this paper.

Practical implications
The research provides a method which is different from the common methods but friendlier to improve the bonding strength of the hydrogel scaffold.

Social implications
This work can help to adjust the mechanical property of the scaffold used in tissue engineering.

Originality/value
This method can improve the bonding strength at weak juncture and give a direction for the design of porous scaffold.
A novel one-variable first-order shear deformation theory for biaxial buckling of a size-dependent plate based on Eringen’s nonlocal differential law
Authors: Malikan Mohammad , Nguyen Van Bac 
Published: October 2018

PurposeThis paper aims to present a new one-variable first-order shear deformation theory (OVFSDT) using nonlocal elasticity concepts for buckling of graphene sheets.Design/methodology/approachThe FSDT had errors in its assumptions owing to the assumption of constant shear stress distribution along the thickness of the plate, even though by using the shear correction factor (SCF), it has been slightly corrected, the errors have been remained owing to the fact that the exact value of SCF has not already been accurately identified. By using two-variable first-order shear deformation theories, these errors decreased further by removing the SCF. To consider nanoscale effects on the plate, Eringen’s nonlocal elasticity theory was adopted. The critical buckling loads were computed by Navier’s approach. The obtained numerical results were then compared with previous studies’ results using molecular dynamics simulations and other plate theories for validation which also showed the accuracy and simplicity of the proposed theory.FindingsIn comparing the biaxial buckling results of the proposed theory with the two-variable shear deformation theories and exact results, it revealed that the two-variable plate theories were not appropriate for the investigation of asymmetrical analyses.Originality/valueA formulation for FSDT was innovated by reconsidering its errors to improve the FSDT for investigation of mechanical behavior of nanoplates.
An Application of MRI to Measure Flow Distribution in Fuel Cell Channels
Authors: Thandi Rajan , Beedie David , Glover Paul , Kannangara Chathura Kasun , Versteeg Henk 
Published: October 2018

This paper presents an application of MRI to measure flow distribution in fuel cell channels. Solid Oxide Fuel Cells (SOFC) are able to efficiently produce electricity directly from the oxidation of the natural gas by electrochemical conversion. The distribution of fuel gas between the high numbers of parallel flow paths within the fuel cell assembly is critically important to ensure high efficiency and uniform conditions within the fuel cell assembly. Practical approaches in conjunction with numerical models are needed to understand and control the physical processes taking place within fuel cells in order to design them to be efficient and reliable. The paper outlines a non-invasive experiment using magnetic resonance imaging (MRI) to measure the distribution of flow within an SOFC subassembly.
The method quantifies the flow distribution by modelling the gas using water at Reynolds similar conditions. Water has a magnetic moment that can be imaged using an MRI scanner. Two-dimensional cross-section scans were taken perpendicular to the direction of flow in the fuel cell channel to measure area and velocity. The study evaluated a range of image resolutions and outlined how the data was processed to provide mass flow rates in each channel using the known fluid properties.
At the highest image resolution the total mass flow rate was within 1% of the independent measurement from the experimental rig. The distribution of flow between the channels showed a similar trend to the computational model. The initial results demonstrate the feasibility for the method to measure flow in the SOFC channels.
FluxTracer: A 3D-Partitioning and Radiant Flux Computer Tool to Analyse the Optical Behaviour of Light Collection and Concentration Subsystems Using High Performance Computers
Authors: Blanco Manuel , Votyakov Evgeny , Christou Chariton , Papanicolas Costas N. , Corsi Clotilde , Pye John 
Published: October 2018

The light collection and concentration subsystem (LCCS) of any concentrating solar thermal (CST) system is composed of the surfaces that collect and concentrate the sunlight and of the input surfaces of the receivers, or receivers’ envelopes, where the light is concentrated. For all commercial CST technologies the LCCS is, together with the power block, the subsystem that has more influence in the overall performance and cost. Thus, its optimization is critical to increase the cost-competitiveness of these systems. This optimization requires, in many cases, the optimization of the position, geometry and size of a very large number of solar collecting and concentrating surfaces as well as the optimization of the shape and size of the input surfaces of the receivers where the sunlight is concentrated. Because a full optimization requires the exploration of a configuration space with a very large number of dimensions, the traditional approach consist in making many initial assumptions to drastically reduce the number of dimensions of the configuration space to a handful, so that the optimization can be carried out using conventional high-end workstations in a matter of hours.
However, to achieve relevant breakthroughs and to substantially increase the cost-competitiveness of CST systems a bolder approach is needed, where sophisticated design and analysis tools, engineered from the start to be used in High Performance Computers (HPC), will be combined with sophisticated optimization strategies targeted to explore and find optimal solutions in very high dimensional configuration spaces.
This paper presents the first of a series of such design and analysis tools. The tool, call Flux Tracer, partitions the three-dimensional space in which the LCC subsystem under analysis is immersed into volumetric pixels (voxels) and computes the radiant energy flux that traverses each voxel as a function of time. It integrates the energy density in every voxel overtime, providing detailed information regarding how the radiant energy flows in space in a given LCC subsystem and in a given period of time. This information is the cornerstone of the highly sophisticated computational LCC subsystem optimization framework The Cyprus Institute (CYI) is developing, in collaboration with the Australian National University (ANU), targeted to be used in HPC’s.