bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychometric Properties of the Revised Death Attitude Profile in a Greek Sample of Nurses
Authors: Bellali Thalia , Giannopoulou Ioanna , Tsourti Zoi , Malliarou Maria , Sarafis Pavlos , Minasidou Evgenia , Papadatou Danai 
Published: September 2018

Background and Purpose:This study aimed to examine the psychometric properties of the Revised Death Attitude Profile (DAP-R) in a sample of Greek nurses and nursing students.Methods:A convenience sample (n = 934) was used from six National Health System hospitals, and two University Schools of Nursing in central and northern Greece completed the Greek version of the DAP-R (Gr-DAP-R).Results:Principal component analysis with varimax rotation revealed a six-factor solution, including approach acceptance, death avoidance, escape acceptance, neutral acceptance, fear of death, and after death concerns. The internal consistency for each of the subscales ranged from 0.64 to 0.88. Intercorrelations between the Gr-DAP-R subscales supported the relative independence of death attitudes dimensions.Conclusions:The Gr-DAP-R can be used as a research and clinical tool in assessing death attitudes among Greek nurses.
The Design and Testing of the Psychometric Properties of the Person Engagement Index Instrument to Measure a Person’s Capacity to Engage in Health Care
Authors: Swartwout Ellen , El-Zein Ashley , Barnett Scott D. , Drenkard Karen 
Published: September 2018

Background and Purpose:Patient engagement has been considered a powerful tool to improve health outcomes. A composite instrument to measure the factors that impact a person’s capacity to engage in his or her health care was an identified gap in the literature. This study developed and tested the psychometric properties of the Person Engagement Index (PEI) instrument.Methods:The instrument was tested among 338 medical–surgical inpatients at four health care systems (five facilities), with psychometric evaluation for validity, reliability, and exploratory factor analysis.Results:Exploratory factor analysis revealed a four-factor solution that accounted for 63.9% of the total variance. Internal consistency results were Cronbach’s α = .896 for the overall scale and each subscale: Engagement in Health Care = .885, Technology Use in Health Care = .854, Proactive Approach to Health Care = .728, and Psychosocial Support = .880.Conclusions:The results of the PEI study indicate that it is a valid and reliable instrument among the adult medical–surgical population. Further testing of the instrument is recommended among other populations and across the care continuum.
Transition From Hospital to Home in Parents of Preterm Infants: Revision, Modification, and Psychometric Testing of the Questionnaire
Authors: Boykova Marina 
Published: September 2018

Background and Purpose:Transition from hospital to home in parents of prematurely born infants can be challenging. This methodological study aimed to develop an instrument to measure transitional problems in parents after hospital discharge.Methods:Kenner’s Transition Questionnaire was modified based on findings of the literature review and a qualitative study. Content validity of the revised tool was determined by a panel of experts, and field testing was conducted via an online survey of parents of preterm infants (N = 704). Exploratory factor analysis (principal axis factoring and direct oblimin rotation) was performed.Results:Results showed four correlated factors in parental transition from hospital to home: Isolation, Worry, Confidence, and Professional Support (17 items total). Factor loadings ranged from .59 to .87, and reliability estimates ranged from .77 to .87.Conclusion:The revised instrument demonstrated adequate psychometric characteristics; further testingand validation of the instrument is warranted.
Collaboration Between Relatives of Older Patients and Nurses in Acute Medical Wards: Confirmatory Factor Analysis of the Revised Family Collaboration Scale
Authors: Lindhardt Tove , Sivertsen Ditte Maria , Smith Louise Lawson , Klausen Tobias Wirenfeldt , Andersen Ove 
Published: September 2018

Background:Relatives of older people are often involved in their care prior to hospital admission, and may hold valuable knowledge which, if involved, could improve decision-making related to care. Hence, collaboration is required and to monitor this, valid and feasible instruments are needed. The Family Collaboration Scale (FCS) was developed for this purpose, and has been found valid and reliable. Our study tested a shorter version, while assessing collaboration between nurses and 388 relatives.Results:The study provided support for reliability and construct validity of the revised scale. Its feasibility may benefit from adjustments, as older relatives, those with less education and those delivering extensive help, were less likely to complete the scale. Collaboration was rated as poor to average. Poor collaboration was significantly more often reported by women and relatives reporting guilt and powerlessness.
Symptom Clusters and Their Impacts on Hospital Readmission in Patients With Heart Failure: A Cross-Sectional Study
Authors: Son Youn-Jung , Won Mi Hwa 
Published: September 2018

Background and Purpose:Readmissions after hospitalization due to multiple symptoms in heart failure (HF) are common and costly. Patients have difficulty differentiating HF symptoms from comorbid illness or aging. Therefore, early identification of symptom clusters could improve symptom recognition and reduce hospital readmission. However, little is known about the relationship between symptom clusters and readmission in HF patients. This study aimed to identify symptom clusters among Korean patients with HF and the relationship between symptom clusters and hospital readmission.Methods:This cross-sectional study included 306 HF outpatients within 12 months after discharge. Exploratory factor analysis was used to identify the symptom clusters. Multiple logistic regression analysis was used to examine the effect of symptom clusters on readmission, after adjusting for sociodemographic and clinical characteristics.Results:Three symptom clusters were identified in HF patients: the “respiratory distress” cluster, “bodily pain and energy insufficiency” cluster, and “circulatory and gastrointestinal distress” cluster. Patients with class III or IV of HF functional class experienced three symptom clusters at a higher level. This study showed that the “bodily pain and energy insufficiency” cluster was the strongest predictor of hospital readmission in HF patients (adjusted odds ratio = 6.59, 95% confidence interval (CI) [1.29, 32.79]).Implications for Practice:A higher level of “bodily pain and energy insufficiency” cluster was associated with hospital readmission in Korean HF patients. Health-care providers should be encouraged to consider patients’ cultural backgrounds to recognize differences in symptom clusters. Further studies are needed to evaluate symptom clusters across international cohorts and their impacts on patients’ outcomes.
تأسيس مقاصد الشريعة التقدمية لرد الفكر الإرهابي والتطرفي (دراسة تحليلية أصولية)
Authors: Nawawi Nawawi 
Published: September 2018

<p align="center"><strong>ملخص</strong></p><p dir="RTL"><strong> </strong>يقوم هذا البحث على إظهار تأسيس مقاصد الشريعة التقدمية لرد الفكر الإرهابي والتطرفي, فإنه لا يكفى الرد له بمجرد مقاصد الشريعة القدامى, لأنها من قبيل الشريعة بالمعنى الضيق وهونطاق الفقه, الذي يمكن أن يفتح التطرف والتشدد, ولذا تتطلب لرده المقاصد الشاملة, التي تقوم على ثلاث دعامات<strong>, أولا</strong>: حفظ التسامح الذي بدوره احتفظت وحدة الأمم, <strong>وثانيا</strong>: نطاق دراستها التي لا تحتوي على الفقه فحسب, بل على العقيدة والتصوف حسب الشريعة بالمعنى الواسع, <strong>وثالثا</strong>: تقديم الأدلة الكلية على الأدلة الجزئية لأن الكلية أقرب الى القطعيات, وبصيغ هذه المقاصد تقوم عليها الحياة الإنسانية في المجتمع التعددي بحيث إذا اختلت واحدة منها, أتاحت إمكانية الفكر الإرهابي والتطرفي.</p>
Islamic Education Unifying Nation
Authors: Saekan Mukhamad 
Published: September 2018

<p>Islamic education for the nation of Indonesia becomes very important because it is known as a diverse nation in various aspects, such as religion, ethnic groups, languages, traditions and even colors. Once differences is not supported by human maturity, it easily leads to conflict of life. Maturity becomes the main factor to set it in order, safe, comfortable and peaceful atmosphere among humans. Maturity is also one indicator of educational success. It is characterized by three things: independence, stability and responsibility. These three are able to realize personal quality and also produce the social quality for humans. Based on Law number 20 year 2003 about National Education System, the position of Islamic education is very strategic because its essence contained also functioned as barometer in arranging the Indonesia national education system. They are found out as the unity of the nation, among others, spiritual power, the ability of self-control, personality, intelligence, noble morals and various life skills that are useful for individual, society and country.</p><pre> </pre>
Farklı Metal (Bakır, Çinko, Kurşun, Kalsiyum ve Mangan) Oksitlerin Sıcak Baca Gazı Kükürt Tutma Aktiviteleri
Authors: KANCA Arzu 
Published: September 2018

Bu çalışma, düşük sıcaklıklarda kükürt tutma aktivitesi bilinen beş metal oksitin (CuO, ZnO, PbO, CaO ve MnO) yüksek sıcaklıkta gösterecekleri kükürt giderme performanslarını test etmeyi amaçlamaktadır. Özellikle yüksek kükürt içeren linyitlerin enerji üretimi amacıyla kullanıldığı ülkemizde yüksek kükürt içeriğinin neden olduğu çevresel sorunlar linyit kullanımı için önemli bir sınırlayıcı engeldir. Bu engeli aşmak için önerilen çözümler ise genellikle açığa çıkan sıcak baca gazlarının soğutulması sonrasında kükürtün metal oksit temelli bir adsorbent yardımıyla tutulmasına dayanmaktadır. Yanma prosesine alternatif olan ve temiz kömür teknolojisi olarak bilinen gazlaştırma prosesleri ise sentez gazı (CO ve H2) üzerinden petrol üretimine imkan vermektedir. Kömürün gazlaştırılmasıyla enerji üreten sistemlerde sıcak baca gazlarının soğutulmasının neden olduğu enerji kayıplarını önlemek için, kükürtü sıcak baca gazlarından uzaklaştırmak gerekir. Bu sebeple kükürtün giderimi için kullanılan metal oksitlerin yüksek sıcaklıkta gösterdikleri kükürt giderim aktiviteleri hem çevresel bir sorunu gidermek hem de enerji verimini artırmak adına son derece önemlidir.
Forward osmosis treatment of effluents from dairy and automobile industry – results from short-term experiments to show general applicability
Authors: Haupt A. , Lerch A. 
Published: September 2018

Abstract
Forward osmosis (FO) is a potential membrane technology to treat wastewater energy efficiently with low fouling. In laboratory-scale experiments, six effluents from a dairy and an automobile production plant were tested to find out if FO is an applicable treatment technology. Permeate flux and reverse salt flux were determined in nine test series with three subsequent 5 h experiments each. In between, the membrane was cleaned with deionized water. Membrane performance tests before each experiment were used to monitor membrane performance and fouling. Samples were analysed and the T/M-value was introduced to indicate which substances caused fouling. Dairy cheese brine was a suitable DS. Here, permeate fluxes were 21.0 and 15.1 L/(m²·h). Automobile cooling tower water and wastewater from cathodic dip painting were also used as DS. However, permeate fluxes were below 1.1 L/(m²·h). The tested FS, reverse osmosis concentrate from dairy wastewater treatment, rinsing water and wastewater from automobile cathodic dip painting, as well as wastewater from automobile paint shop pre-treatment, showed good performance regarding the permeate flux of between 7.9 and 19.4 L/(m²·h). Membrane performance test showed that some of the effluents lead to permeate flux reduction due to fouling. Different cleaning-in-place methods were examined. Eventually, permeate flux was restored.
Effect of kaolin on floc properties for reactive orange removal in continuous coagulation process
Authors: Zhao Jianhai , Wang Anmin , Wei Lei , Ge Wenqi , Chi Yongzhi , Lai Yanping 
Published: September 2018

Abstract
Magnesium hydroxide was used as a coagulant for treating reactive orange wastewater in a real continuous process. Effects of kaolin on coagulation performance and floc properties were investigated with controlled experiments through floc size distribution, zeta potential, scanning electron microscopy and Fourier transform infrared spectroscopy. Kaolin had significant influence on magnesium hydroxide-reactive orange floc formation and growth. The results showed that average floc size reached 16.31, 12.88 and 20.50 μm, respectively, in the rapid mixer, flocculation basin and sedimentation tank when kaolin concentration was 10 mg/L and reactive orange initial concentration was 0.25 g/L. The floc size tended to increase with the increase of kaolin suspension to 10 mg/L. All of the flocs under investigation showed that floc breakage led to decreased average floc size and remained stable in the flocculation basin. Reactive orange and kaolin could be removed effectively in the continuous coagulation process. Reactive orange was adsorbed in the surface of magnesium hydroxide through charge neutralization and adsorption.
Arsenate removal from aqueous solution using chitosan-coated bentonite, chitosan-coated kaolinite and chitosan-coated sand: parametric, isotherm and thermodynamic studies
Authors: Futalan Cybelle M. , Huang Yu-Shen , Chen Jheng-Hong , Wan Meng-Wei 
Published: September 2018

AbstractIn the present work, the removal efficiency of As(V) from aqueous solution using chitosan-coated bentonite (CCB), chitosan-coated kaolinite (CCK) and chitosan-coated sand (CCS) was evaluated. The chitosan-based adsorbents were characterized using scanning electron microscopy, Fourier-transform infrared spectroscopy, the Brunauer-Emmett-Teller method and thermogravimetric analysis. Kinetic studies revealed that As(V) uptake using CCB, CCK and CCS fitted well with the pseudo-second order equation (R2 ≥ 0.9847; RMSE ≤ 9.1833). Equilibrium data show good correlation with the Langmuir model (R2 ≥ 0.9753; RMSE ≤ 8.5123; SSE ≤ 16.2651) for all adsorbents, which implies monolayer coverage onto homogenous energy sites. The Langmuir adsorption capacity for As(V) at pH 7.0 was determined to be 67.11, 64.85, and 16.78 mg/g for CCB, CCK and CCS, respectively. Thermodynamic studies show that As(V) uptake is exothermic in nature using CCK and endothermic using CCB and CCS. Moreover, adsorption of As(V) was feasible and spontaneous for CCB and CCS at 298 to 328 K. Results show that CCB is the most effective adsorbent in the removal of As(V) from water due to its high surface area and large pore diameter.
Preparation and characterization of chitosan/Fe2O3 nano composite for the adsorption of thorium (IV) ion from aqueous solution
Authors: Broujeni B. Rouhi , Nilchi A. , Hassani A. H. , Saberi R. 
Published: September 2018

Abstract
In this study, novel chitosan/Fe2O3nano composite Ch/Fe-Onc was synthesized and evaluated as an adsorbent for removing thorium (IV) (Th4+) ion from aqueous solution. The Ch/Fe-Onc was characterized by X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET), Fourier transform infrared (FTIR) and scanning electron microscopy (SEM). Response surface methodology (RSM) was used in the optimization of Th4+ adsorption for parameters such as pH, the initial metal ion concentration (Th4+ concentration) and contact time. The statistical measures (i.e. analysis of variance, R2, the lack of fit test and the P value) specify that the developed model is proper. Furthermore, the adsorption kinetics was well defined by the pseudo-second-order equation, while the adsorption isotherms were better fitted by the Langmuir model. The adsorption capacity of Ch/Fe-Onc was 430 mg Th4+g−1 composite which leads to 99% removal at 25 °C. Moreover, thermodynamic parameters which state the natural and endothermic nature of the reactions were determined. The loaded Th4+ can be easily regenerated with HNO3 and the Ch/Fe-Onc can be used repeatedly without any significant reduction in its adsorption capacity. The desorption level of Th4+ from the Ch/Fe-Onc by using 0.1 M HNO3, was more than 95%.
Evaluation of two statistical approaches for estimating pollutant loads at adjacent combined sewer overflow structures
Authors: Ly Duy Khiem , Maruéjouls Thibaud , Binet Guillaume , Litrico Xavier , Bertrand-Krajewski Jean-Luc 
Published: September 2018

Abstract
Quantifying pollutant loads from combined sewer overflows (CSOs) is necessary for assessing impacts of urban drainage on receiving water bodies. Based on data obtained at three adjacent CSO structures in the Louis Fargue catchment in Bordeaux, France, this study implements multiple linear regression (MLR) and random forest regression (RFR) approaches to develop statistical models for estimating emitted loads of total suspended solids (TSS). Comparison between hierarchical clustering selection and random selection of CSO events for model calibration is included in model development. The results indicate that selection of the model's explanatory variables depends on both the type of approach and the CSO structure. By using the cluster technique to select representative events for model calibration, model predictability is generally improved. For the available dataset, MLR may have advantages over RFR in terms of verification performance and lower range of error due to splitting events for calibration and verification. But RFR model uncertainty bands are considerably narrower than the MLR ones.
Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis
Authors: Orekhov Alexander N. , Oishi Yumiko , Nikiforov Nikita G. , Zhelankin Andrey V. , Dubrovsky Larisa , Sobenin Igor A. , Kel Alexander , Stelmashenko Daria , Makeev Vsevolod J. , Foxx Kathy , Jin Xueting , Kruth Howard S. , Bukrinsky Michael 
Published: September 2018

Background:
A hallmark of atherosclerosis is its complex pathogenesis, which is dependent on altered
cholesterol metabolism and inflammation. Both arms of pathogenesis involve myeloid cells. Monocytes migrating
into the arterial walls interact with modified low-density lipoprotein (LDL) particles, accumulate cholesterol and
convert into foam cells, which promote plaque formation and also contribute to inflammation by producing proinflammatory
cytokines. A number of studies characterized transcriptomics of macrophages following interaction
with modified LDL, and revealed alteration of the expression of genes responsible for inflammatory response and
cholesterol metabolism. However, it is still unclear how these two processes are related to each other to contribute
to atherosclerotic lesion formation.

Methods:
We attempted to identify the main mater regulator genes in macrophages treated with atherogenic
modified LDL using a bioinformatics approach.

Results:
We found that most of the identified genes were involved in inflammation, and none of them was
implicated in cholesterol metabolism. Among the key identified genes were interleukin (IL)-7, IL-7 receptor, IL-
15 and CXCL8.

Conclusion:
Our results indicate that activation of the inflammatory pathway is the primary response of the
immune cells to modified LDL, while the lipid metabolism genes may be a secondary response triggered by
inflammatory signalling.
Advanced Glycation End Products (AGEs), Glutathione and Breast Cancer: Factors, Mechanism and Therapeutic Interventions
Authors: Sharma Anil K. , Sharma Var R. , Gupta Girish K. , Ashraf Ghulam Md. , Kamal Mohammad A. 
Published: September 2018

Background:
Advanced Glycation End products (AGEs) are basically the end result of glycation of proteins
and/or lipids in the presence of sugars. Specific cases of hyperglycemia have been reported with increased propensity
of generation of AGEs. Many chronic and deadly diseases such as diabetes, cancer and neurodegenerative
disorders have been known to be caused as a result of generation of AGEs. The role of glutathione (GSH) metabolism
and its intricate association with AGEs have also been well established in breast cancer prognosis and treatment.
To understand the etiology, mechanism and production of AGEs along with clinical relevance of Receptors for Advanced
Glycation End-products (RAGE) and RAGE ligands, their interplay with GSH is of paramount importance
especially in relation to breast cancer.

Methods:
The available literature using PubMed, National Library of Medicine database, Web of Science and SCOPUS
indexed, Science Direct and other prestigious journals have been systematically reviewed using the keywords:
advanced glycation end-products, breast cancer, glutathione RAGE, and AGEs inhibitors. This narrative review of all
the relevant papers with significant citations has led us to have greater insight into the action mechanism and potential
therapeutic significance of AGEs inhibitors.

Results:
Targeting breast cancer with the specific immunoglobulins and with other therapeutic interventions is
needed to inhibit the generation of AGEs and manage glutathione expression, thus having strong implications in the
management of breast cancer. Many RAGE ligands such as HMGB1, S100P, S100A8, S100A9 etc. have been
known to enhance RAGE expression which may further lead to increased proliferation, migration and metastatic
nature of tumor cells. Hence, RAGE and RAGE ligands in a close linkup with GSH may prove to be effective therapeutic
markers of severity of breast cancer and for angiogenesis of tumor.

Conclusion:
This review provides a strong platform to comprehend the etiology, mechanism and production of
AGEs and glutathione along with the agents which can block their production, paving a way for the therapeutic intervention
and an amicable solution to treat and manage breast cancer.
Synthesis and Biological Evaluation of Novel Osthol Derivatives as Potent Cytotoxic Agents
Authors: Farooq Saleem , Banday Javid A. , Hussain Aashiq , Nazir Momina , Qurishi Mushtaq A. , Hamid Abid , Koul Surrinder 
Published: September 2018

Background:
Natural product, osthol has been found to have important biological and
pharmacological roles particularly having inhibitory effect on multiple types of cancer.

Objective:
The unmet needs in cancer therapeutics make its derivatization an important and exciting
field of research. Keeping this in view, a whole new series of diverse analogues of osthol (1)
were synthesized.

Method:
All the newly synthesized compounds were made through modification in the lactone
ring as well as in the side chain of the osthol molecule and were subjected to anti-proliferative
screening through 3-(4,5-Dimethylthiazol-yl)-diphenyl tetrazoliumbromide (MTT) against four
different human cancers of diverse origins viz. Colon (Colo-205), lung (A549), Leukemia (THP-
1) and breast (MCF-7) including SV40 transformed normal breast epithelial cell (fR-2).

Results:
Interestingly, among the tested molecules, most of the analogs displayed better antiproliferative
activity than the parent Osthol 1. However, among all the tested analogs, compound
28 exhibited the best results against leukemia (THP1) cell line with IC50 of 5µM.Compound 28
induced potent apoptotic effects and G1 phase arrest in leukemia cancer cells (THP1). The population
of apoptotic cells increased from 13.8% in negative control to 26.9% at 8μM concentration
of 28. Compound 28 also induced a remarkable decrease in mitochondrial membrane potential
(ΛΨm) leading to apoptosis of the cancer cells.

Conclusion:
A novel series of molecules derived from natural product osthol were synthesized,
wherein compound 28 was found to be most effective against leukemia and with 10 fold less toxicity
against normal cells. The compound induced cancer inhibition mainly through apoptosis and
thus has a potential in cancer therapeutics.