bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current approaches to neurosurgical treatment for drug-resistant focal epilepsy in adults
Authors: Narodova E. A. , Narodov A. A. , Shnayder N. A. , Dmitrenko D. V. , Strotskaya I. G. 
Published: July 2018

The review is dedicated to the problems of current neurosurgical treatment for drug-resistant epilepsy in the adult population of Russia and foreign countries. The literature published in the period 2010–2017 was sought in Russian and foreign databases. This review included 58 only full-text publications. The search results have shown that despite advances in neurosurgery for drug-resistant epilepsy and the development of new surgical procedures, the problem of this disease has not yet been fully resolved today. This is evidenced by fairly high global prevalence rates in patients with postoperative epilepsy resistant to antiepileptic therapy. The literature analysis has revealed that the mean prevalence of postoperative epilepsy is 69%. This indicator may vary according to the type of an epileptogenic structural lesion and its location in the brain. However, despite the rapid development of epilepsy surgery, currently there is still a low surgical activity in the treatment of patients with drugresistant epilepsy. Of importance is also the presence of postoperative complications, including various infectious complications and neurological deficit. Taking into account the high rate of postoperative epilepsy, it is concluded that it is appropriate to develop postoperative rehabilitation methods for patients with drug-resistant epilepsy.
A review of seismic observations of Kepler and K2-Observed sdBV stars
Authors: Reed Michael D. , Baran Andrzej S. , Telting John H. , Østensen Roy H. , Jeffery Christopher S. , Kern Joshua W. , Ketzer Laura , Crooke John , Slayton A. 
Published: July 2018

Abstract
This paper reviews recent seismic findings from Kepler and K2 data. Using three years of short cadence Kepler (K1) data, it is possible to examine time evolution of pulsations in an unprecedented way. While K2 observations are shorter, only three months, they are important as they are finding more sdBV stars than K1 did. Most importantly, K2 is discovering more p−mode pulsators with coverage not possible to get from the ground.
National surveys on 15 quality indicators for the total testing process in clinical laboratories of China from 2015 to 2017
Authors: Duan Min , Ma Xudong , Fan Jing , Guo Yanhong , Wang Wei , Zhao Haijian , Ye Yuanyuan , Fei Yang , He Falin , Wang Zhiguo , Zhang Zongjiu 
Published: July 2018

AbstractBackgroundAs effective quality management tools, quality indicators (QIs) are widely used in laboratory medicine. This study aimed to analyze the results of QIs, identify errors and provide quality specifications (QSs) based on the state-of-the-art.MethodsClinical laboratories all over China participated in the QIs survey organized by the National Health Commission of People’ Republic of China from 2015 to 2017. Most of these QIs were selected from a common model of QIs (MQI) established by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All participants were asked to submit general information and original QIs data through a medical quality control data collection system. The results of QIs were reported in percentages and sigma, except turnaround time (TAT) which was measured in minutes. The 25th, 50th and 75th percentiles were, respectively, calculated as three levels of QSs, which were defined starting from the model proposed during the 1st Strategic Conference of the EFLM on “Defining analytical performance 15 years after the Stockholm Conference on Quality Specification in Laboratory Medicine”.ResultsA total of 76 clinical laboratories from 25 provinces in China continuously participated in this survey and submitted complete data for all QIs from 2015 to 2017. In general, the performance of all reported QIs have improved or at least kept stable over time. Defect percentages of blood culture contamination were the largest in the pre-analytical phase. Intra-laboratory TAT was always larger than pre-examination TAT. Percentage of tests covered by inter-laboratory comparison was relatively low than others in the intra-analytical phase. The performances of critical values notification and timely critical values notification were the best with 6.0σ. The median sigma level of incorrect laboratory reports varied from 5.5σ to 5.7σ.ConclusionsQSs of QIs provide useful guidance for laboratories to improve testing quality. Laboratories should take continuous quality improvement measures in all phases of total testing process to ensure safe and effective tests.
Quasi 3-D trigonometric plate theory for bending analysis of EG plates resting on Pasternak foundations
Authors: Radwan Ahmed F. , Zenkour Ashraf M. 
Published: July 2018

Abstract
This paper deals with the bending analysis of exponentially graded material (EGM) plates resting on two-parameter elastic foundations according to a trigonometric shear deformation plate theory (TPT) using Navier’s technique. The normal and shear deformations are both includes. The present TPT does not need a shear correction factors. The material properties of plate like, Lamé’s coefficients convert exponentially in a given constant orientation. The equilibrium equations according to the EG plate resting on Pasternak foundations are presented. Numerical results for the EG thick plate on elastic foundations are presented. A good comparison of results with those being in the literature. The influences played by Winkler and Pasternak parameters, side-to-thickness ratio, inhomogeneity parameter and aspect ratio on the bending responses of EG plates are debated.
Surfactants in Klodnica River (Katowice, Poland). Part II. Quaternary Ammonium Compounds
Authors: Ruman Marek , Olkowska Ewa , Pytel Sławomir , Polkowska Żaneta 
Published: July 2018

Abstract
The paper presents methods of determination of analytes of the cation group (alkyl benzyl dimethyl ammonium (BDDA-C12-C16), alkyl trimethyl ammonium (TMA), hexadecyl piridinium (HP)) in surface water and bottom sediment samples. In the sample preparation phase the solid phase extraction (SPE) or accelerated solvent extraction/ultrasound assisted extraction (ASE/UAE)-SPE technique was used and in the identification phase and quantitative determination of analytes phase - ion chromatography technique (combined with a conductivity detector (CD)). The determined concentrations were in the range below the determined method detection limit (MDL) or method quantification limit (MQL) figures up to 0.142 ±0.023 mg/dm3 or 2014 ±10 μg/kg (liquid and solid samples, respectively). Comparing concentrations of individual analytes found in liquid and solid environmental samples we may notice that surfactants containing a shorter alkyl chain in their molecules were found in higher concentrations in liquid samples (hydrophobicity increasing with the chain length).
Sustainability of Waste Materials in Affinity with Ecologically Sustainable Development: A Case Study of Kosovo
Authors: Bajçinovci Bujar 
Published: July 2018

Abstract
Using our natural resources, we produce much waste that can be recycled as a useful resource, which further contributes to climate change. Kosovo, generally produces a huge amount of waste, particularly Prishtina as the capital its capital city. The study presented in this paper investigated the high-rise buildings in Ulpiana neighbourhood of the city of Prishtina and waste disposals in Kosovo, focusing on the challenges of urban waste management, particularly on the recycling of high-rise urban generated waste. The research methods consist of empirical observation through urban spatial zone. Researched model of high-rise buildings, surveyed the land use, and recycling process of a total generated waste of 778.8 kg daily/per one structure. According to the conceptual and calculated findings strengthened with awareness for sustainable consumption, and proper urban strategy for implementing the recycling waste materials, it is indicated that the waste amount can be decreased and recycled for about 25 % from the total waste generated daily.
Response of Pulses to Seed or Soil Application of Rhizobial Inoculants
Authors: Martyniuk Stefan , Kozieł Monika , Gałązka Anna 
Published: July 2018

Abstract
In micro-plot experiments growth, nodulation and seed yields of pea, yellow lupine and soybean grown in a soil colonized by high populations of pea and lupine rhizobia and low population of soybean rhizobia as influenced by seed or soil application of rhizobial inoculants were studied. The studied inoculation method had no significant effects on root nodule numbers, plant growth at the flowering stage and on seed yields of pea and yellow lupine in comparison to uninoculated control treatments. In the case of soybean seed and soil inoculation with soybean rhizobia (Bradyrhizobium japonicum) resulted in a significant increase of nodulation intensity, fresh and dry mass of shoots at the flowering stage as well as pod numbers and soybean seed yields at harvest. Soybean grown on plots in which soil was inoculated with the symbiotic bacteria gave seed yield by about 57 % higher as compared to that of soybean grown from seed inoculated with the rhizobia and by 169 % higher than when this crop was grown on the control (uninoculated) plots.
On the Attempt to Implement Social Addressability within a Robotic System
Authors: Graf Philipp , Marquardt Manuela , Compagna Diego 
Published: July 2018

Abstract
We conducted a Human-Robot Interaction (HRI) study during a science event, using a mixed method experimental approach with quantitative and qualitative data (adapted version of Godspeed Questionnaire and audio-visual material analysed videographically). The main purpose of the research was to gather insight into the relevance of the so-called “point of interaction” for a successful and user-friendly interaction with a non-anthropomorphic robot. We elaborate on this concept with reference to sociological theories under the heading of “addressability” and “social address” and generate hypotheses informed by former research and theoretical reflections. We implement an interface on our robot system, comprising two LEDs, which indicate the status of the robot/interaction, and which might possibly serve as basal form of embodied social address. In one experimental condition, the movements were accompanied by a light choreography, the other one was conducted without the LEDs. Our findings suggest a potential relevance of social address for the interaction partner to receive additional information, especially if the situation is a contingent one. Nevertheless, the overall rating on the Godspeed scales showed no significant differences between the light conditions. Several possible reasons for this are discussed. Limitations and advantages are pointed out in the conclusion.
Wicked, Open, Collaborative: Why Research through Design Matters for HCI Research
Authors: Berger Arne , Totzauer Sören , Lefeuvre Kevin , Storz Michael , Kurze Albrecht , Bischof Andreas 
Published: July 2018

Abstract
In contrast to the first and second wave of Human Computer Interaction, the third wave grapples with wicked problems. However, re-solutions to wicked problems embodied in artifacts frame and change the understanding of the problem itself. Research through Design (RtD) is a constructive methodology to understand this interplay of problem framing through designing artifacts. RtD is also suited to resurface the theory within those artifacts through annotation. These annotations expose and emphasize qualities, values and assumptions held within artifacts by its creators. In addition to those modes for annotation, we will suggest two additional abstract frames through which RtD artifacts can be further annotated: Open Research Agenda and Interdisciplinarity. We will apply both frames to one research artifact, Loaded Dice to distill qualities from this artifact’s framing. Through this we will show how creating and deploying an artifact can change its environment which also includes its creators.
Modeling of Fluid Bed Reactor of Ethylene Di Chloride Production in Abadan Petrochemical Based on Three-Phase Hydrodynamic Model
Authors: Faghih Seyed Mohammad , Kianfar Ehsan 
Published: July 2018

Abstract
The catalytic process of ethylene oxychlorination can be split into two steps,uiz.ethylenechlorination with the reduction of cupric chloride and reoxidation of the cuprous chloride by hydrogen chloride and oxygen. The transient process of 1,2-dichloroethane formation was observed by selected ion chromatography using a mass spectrometer. While the reaction exhibited first-order kinetics in regard to the concentration of cupric chloride, the dependency on ethylene concentration was interpreted by a Wachi & Yousuke and Carrubba mechanism. Optimal performance was achieved by impregnating ea. 5 wt % of copper into y-alumina powder and 64% of the copper contained in the alumina powder contributed to the formation of 1,2-dichloroethane.this study, constant adverse reactions were calculated due to the experimental data obtained from Abadan Petrochemical Unit and the speed equation of Wachi was modified. The reaction occurs at three phases of bubble, cloud, and emulsion and by increasing temperature and input gas velocity and keeping all the other parameters constant in several steps, the substrate was investigated and the conversion of ethylene and gross value for each test were calculated. Thus, with the determination of kinetic and dynamic parameters, the proper mathematical model was chosen and using this model, the conversion percent of ethylene was calculated and its actual amount and the percentage of error were calculated and compared based on information obtained from Abadan Petrochemical reactor under different conditions.
Integrationsmechanismen des Blended Learning im Fremdsprachenunterricht. Eine explorative Fallstudie
Authors: Pust Daniel 
Published: July 2018

ZusammenfassungVerzahnung ist in Bezug auf Blended Learning (BL) ein Schlagwort, das die komplexe Relation von Präsenz- und Online-Lernen versinnbildlicht. Dass das Verhältnis der Lernmodi zueinander ein kritischer Faktor ist und deren wechselseitiger Einbeziehung eine wesentliche Funktion zukommt, darauf weisen mehrere Studien hin, die Probleme im Lernprozess auf ein Defizit an Integration zurückführen. Nach wie vor ist das Phänomen der Integration in BL-Umgebungen theoretisch nur ansatzweise erforscht. Um diese Forschungslücke zu schließen, untersucht diese Fallstudie mittels eines theoriegenerierenden Ansatzes Verfahren und Techniken, die Verbindungen zwischen den unterschiedlichen Lernmodi des BL etablieren. Auf Grundlage empirischer Daten, die zu einer BL-Unterrichtseinheit in einem DaF-Sprachkurs an einer irischen Universität erhoben wurden, wird ein Modell zu Integrationsmechanismen entwickelt, das Lehrenden wie Forschenden als Werkzeug dazu dienen kann, Integration in BL-Arrangements quantitativ wie auch qualitativ zu erfassen.
Effect of mud pack to eyes on psychological variables in healthy volunteers: a pilot randomized controlled trial
Authors: Jogdand Reshma , Mooventhan A. , Manjunath NK 
Published: July 2018

Abstract

Background
Mud pack is one of the fundamental therapeutic procedures used in naturopathy to treat various diseases. There is a lack of scientific evidence for the use of mud-pack application in psychological variables. The present study aims at evaluating the effect of mud pack to eyes on psychological variables in healthy volunteers.

Materials and methods
Sixty healthy individuals with the age varied from 18 to 21 years were recruited and randomly divided into either mud-pack group (n=30) or wet-pack group (n=30). Mud-pack group received mud pack to eyes and wet-pack group received wet pack to eyes for a duration of 30 min/session (a total of 15 sessions). Psychological assessments like Mindful Attention Awareness Scale (MAAS), Perservative Thinking Questionnaire (PTQ) and Positive and Negative Affect Scale (PANAS) were taken before and after the intervention. Statistical analysis was performed using statistical package for the social sciences, version 16.

Results
Result of this study showed a significant reduction in PTQ score and PANAS negative score in both mud-pack and wet-pack groups. But, a significant increase in MAAS score was observed only in the mud-pack group, unlike wet-pack group. However, there was no significant difference found in between group analysis.

Conclusions
Result suggests that though both mud pack and wet pack to eyes reduced the scores of PTQ and negative affects, only mud pack to eyes increased the state of mindfulness in healthy individuals.
In vitro anticholinesterase, antimonoamine oxidase and antioxidant properties of alkaloid extracts from kola nuts (Cola acuminata and Cola nitida)
Authors: Oboh Ganiyu , Ademosun Ayokunle O. , Ogunsuyi Opeyemi B. , Oyedola Esther T. , Olasehinde Tosin A. , Oyeleye Sunday I. 
Published: July 2018

Abstract

Background
The development of cholinesterase (ChE) and monoamine oxidase (MAO) inhibitors for management of neurodegenerative diseases such as Alzheimer’s disease (AD) has come with their undesirable side effects. Hence, research for potent but natural ChE and MAO inhibitors with little or no side effects is essential. This study investigated the potentials of alkaloid extracts from two Cola species as nutraceuticals for prevention and management of AD.

Methods
Alkaloid extracts were obtained from two Cola species (Cola nitida [KN] and Cola acuminata [KA]) by solvent extraction method. The extracts were characterized for their alkaloid contents using gas chromatography (GC). The effects of the extracts on ChE and MAO activities were investigated in vitro. Also, the extracts’ ability to inhibit Fe2+-induced lipid peroxidation in rat brain homogenate, scavenge DPPH and OH radicals, as well as chelate Fe2+ were determined.

Results
GC characterization revealed the presence of augustamine and undulatine as the predominant alkaloids in the extracts. There was no significant (P > 0.05) difference in the inhibitory effects of the extracts on ChE activities. However, KA extract exhibited significantly higher (P < 0.05) MAO inhibitory effect than KN. Also, KA extract inhibited Fe2+- induced malondialdehyde (MDA) production in rat brain homogenate more significantly than KN, while there was no significant difference in DPPH and OH radicals scavenging, as well as Fe2+-chelating abilities of the extracts.

Conclusions
Our findings revealed that KN and KA alkaloid extracts exhibited significant effect in vitro on biological pathways that may contribute to neuroprotection for the management of neurodegenerative diseases.
Testicular and spermatotoxic potential of methanol extract of red cultivar Allium cepa in rats
Authors: Adeoye Oyewusi J. , Olayinka Oridupa A. , Bernard Saba A. , Sikiru Olurode A. , Kofoworola Oyewusi I. , Olufemi Olukunle J. , Adekunle Adebiyi A. 
Published: July 2018

Abstract

Background
In both human and animals, especially in food and companion animal breeding farms, infertility is normally a challenge of great concern. Males have been found to be solely responsible for about 20–30% of infertility cases. Allium cepa (Onion), being one of the highly consumed spices worldwide, is usually overlooked as a possible reproductive toxicant. Most research on A. cepa document its medicinal effects. This study focused on toxicity potential of A. cepa to the male reproductive system. Spermatozoa morphological characteristics and testicular histopathology of male Wistar rats were accessed following administration of A. cepa methanol extract for 14 and 28 days.

Methods
The rats (55) were divided into groups A, B and C of 25, 25 and 5 rats, respectively. Group C served as the control and was administered distilled water (10 ml/kg), while groups A and B were subdivided into five groups of five rats each. Group A and B were administered A. cepa extract at various graded doses for 14 days and 28 days, respectively.

Results
The results revealed significantly increased (p < 0.05) percentage spermatozoa abnormalities, with significantly lower spermatozoa concentration, mass activity and percentage sperm motility when compared with the control group.

Conclusions
Conclusively, excessive (>100 mg/kg) and prolonged (>7 days) consumption or administration of Allium cepa (onion), including nutraceutical preparations of A. cepa has spermatotoxic effect and may damage germinal epithelial cells of the testicles. Toxicity of A. cepa is dose-dependent and beneficial effects may be maximized at doses ≤100 mg/kg for ≤7 consecutive days.
Incorporating SDC Module for ISI Compensation for a Long-Haul Co-OFDM System
Authors: Chauhan Anu , Vaish Arti 
Published: July 2018

Abstract
With the increase in demand of bandwidth hungry applications, it is recommended to develop a high data rate system for long-haul coherent optical orthogonal frequency division multiplexing (CO-OFDM). At a very high data rate, CO-OFDM signal experiences deterioration. At 50 Gbps, the signal experiences ISI effect and in order to overcome this ISI effect, a prolonged system has been developed to reach optimal ISI compensation technique. One of the prominent and competent techniques to enhance system performance is (SDCM) symmetrical dispersion compensation module. In order to make system more bandwidth efficient 4-QAM (Quadrature Amplitude Modulation) with gray coding is applied and manual adjustments are done at receiver phase to decrease error vector magnitude (EVM). OFDM data stream is successfully transmitted over a distance of 4,000 km to compete the demand of long-haul CO-OFDM system. With different launch powers and laser linewidths, the performance of the system is enhanced in terms of Q-factor, SNR and EVM.
Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation
Authors: Rognlien Anne Gro W. , Wollen Embjørg J. , Atneosen-Åsegg Monica , Suganthan Rajikala , Bjørås Magnar , Saugstad Ola Didrik 
Published: July 2018

Abstract

Background
8-Oxoguanine DNA-glycosylase 1 (OGG1) and mutY DNA glycosylase (MUTYH) are crucial in the repair of the oxidative DNA lesion 7,8-dihydro-8-oxoguanine caused by hypoxia-reoxygenation injury. Our objective was to compare the gene expression changes after hypoxia-reoxygenation in neonatal Ogg1-Mutyh double knockout mice (OM) and wildtype mice (WT), and study the gene response in OM after hyperoxic reoxygenation compared to normoxic.

Methods
Postnatal day 7 mice were subjected to 2 h of hypoxia (8% O2) followed by reoxygenation in either 60% O2 or air, and sacrificed right after completed reoxygenation (T0h) or after 72 h (T72h). The gene expression of 44 a priori selected genes was examined in the hippocampus/striatum and lung.

Results
We found that OM had an altered gene response compared to WT in 21 genes in the brain and 24 genes in the lung. OM had a lower expression than WT of inflammatory genes in the brain at T0h, and higher expression at T72h in both the brain and lung. In the lung of OM, five genes were differentially expressed after hyperoxic reoxygenation compared to normoxic.

Conclusion
For the first time, we report that Ogg1 and Mutyh in combination protect against late inflammatory gene activation in the hippocampus/striatum and lung after neonatal hypoxia-reoxygenation.