bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functionalization of 2D materials for enhancing OER/ORR catalytic activity in Li–oxygen batteries
Authors: Ostadhossein Alireza , Guo Jack , Simeski Filip , Ihme Matthias 
Published: August 2019

AbstractA major barrier toward the practical application of lithium-oxygen batteries is the high overpotential caused by the precipitation of oxygen-reduction products at the cathode, resulting in poor cyclability. By combining first-principle calculations and reactive molecular dynamics simulations, we show that surface functionalization of 2D MXene nanosheets offers a high degree of tunability of the catalytic activity for oxygen-reduction and oxygen-evolution reactions (ORR/OER). We show that the controlled creation of active vacancy sites on the MXene surface enhances ORR in excess of a factor of 60 compared to graphene-based cathode materials. Furthermore, we find that increasing the ratio of fluorine vs. oxygen termination of the functionalized Ti4N3-MXene catalyst reduces the charge overpotential by up to 70% and 80% compared with commercial platinum-on-carbon and graphene catalysts, respectively. These results provide direct guidance toward the rational design of functionalized 2D materials for modulating the catalytic activity for a wide range of electrocatalytic applications.
Common responses of fish embryos to metals: an integrated analysis of transcriptomes and methylomes in zebrafish embryos under the stress of copper ions or silver nanoparticles
Authors: Tai ZhiPeng , Guan PengPeng , Wang ZiYang , Li LingYa , Zhang Ting , Li GuoLiang , Liu Jing-Xia 
Published: August 2019

AbstractRecently, the responses of embryos to Cu2+ or AgNP stresses have been investigated, but few studies have been performed on the common responses of embryos to both Cu2+ and AgNPs, the same kind of stressor metal. In this study, a large number of commonly down-regulated and up-regulated differentially expressed genes (DEGs) were revealed in both Cu2+- and AgNP-stressed embryos. The down-regulated DEGs were enriched in myosin complex and muscle structure development, ion transport and metal ion binding, transmission of nerve impulses, etc., and the up-regulated DEGs were enriched in heart development, iron ion binding, etc. Based on the whole-genome bisulfite sequencing (WGBS) in both Cu2+- and AgNP-stressed embryos, a total of 57 and 64 differentially methylated genes (DMGs) were identified in Cu2+ embryos and AgNP embryos, with 15 and 12 of them being common ion-relevant genes, respectively. The correlation of the gene transcriptional expression and the methylated status of some common DMGs were further verified. The integrated analysis of transcriptomes and methylomes in zebrafish embryos stressed with Cu2+ or AgNPs revealed for the first time their common transcriptional and methylomic responses to the same kind of stressor metals, and revealed that ion-relevant genes were mostly differentially expressed and methylated genes in both Cu2+- and AgNP-stressed embryos.
Radiation phenomenon for large meteoroids
Authors: Park C. 
Published: August 2019

Aims. The relationship between the intrinsic properties of a large meteoroid, that is, mass, density, chemical composition, and flight velocity, and its spectrum are identified.
Methods. Assuming thermochemical equilibrium and inviscid flow and using a quasi-one-dimensional approach, the flow-field and radiative transfer problems are solved from the ablating wall of a meteoroid to the observer on the ground.
Results. The study discovers that the precursor region immediately ahead of the shock layer absorbs nitrogen and oxygen lines, and thereby modifies the spectrum received by the ground observer. The study leads to a computer code with which the observed spectra and light-curves for Benesov and Sumava meteoroids are numerically and approximately reproduced with the help of a meteoroid fragmentation theory. Luminous efficiency value is obtained as a byproduct.
Onset of planet formation in the warm inner disk
Authors: Demirci Tunahan , Krause Corinna , Teiser Jens , Wurm Gerhard 
Published: August 2019

Aims. Collisional growth of dust occurs in all regions of protoplanetary disks with certain materials dominating between various condensation lines. The sticking properties of the prevalent dust species depend on the specific temperatures. The inner disk is the realm of silicates spanning a wide range of temperatures from room temperature up to sublimation beyond 1500 K.
Methods. For the first time, we carried out laboratory collision experiments with hot levitated basalt dust aggregates of 1 mm in size. The aggregates are compact with a filling factor of 0.37 ± 0.06. The constituent grains have a wide size distribution that peaks at about 0.6 μm. Temperatures in the experiments are varied between approximately 600 and 1100 K.
Results. Collisions are slow with velocities between 0.002 and 0.15 m s−1, i.e., relevant for protoplanetary disks. Aside from variations of the coefficients of restitution due to varying collision velocities, the experiments show low sticking probability below 900 K and an increasing sticking probability starting at 900 K.
Conclusions. This implies that dust can grow to larger size in hot regions, which might change planet formation. One scenario is an enhanced probability for local planetesimal formation. Another scenario is a reduction of planetesimal formation as larger grains are more readily removed as a consequence of radial drift. However, the increased growth at high temperatures likely changes planetesimal formation one way or the other.
Retrofit solutions for an historic building integrated with geothermal heat pumps
Authors: Carnieletto Laura , Emmi Giuseppe , Artuzzi Marco , Piazza Maria Celeste , Zarrella Angelo , De Carli Michele 
Published: August 2019

Since the beginning of this century, according to EPBD Directive, Italian legislation has been focusing on existing buildings’ retrofit, as they represent a large part of the national building stock. In this context, the most difficult challenge is preserving heritage and obtaining energy saving at the same time, which is the aim of the European Standard EN 16883 published in 2017. Currently there are few energy efficiency actions that can be applied to improve the energy performance of these buildings, due to the strict regulation on ‘protected status’.
The case study presented in this paper gives an overview of refurbishment solutions that can get around Italian legislation for one of the oldest heritage buildings in Padova. The building complex that can be seen nowadays is the result of the grouping of several surrounding buildings, renaissance palaces and medieval towers. Energy simulations have been implemented using EnergyPlus software. The thermal behaviour of the building has been investigated considering the peculiarities of the envelope and real weather data. Internal loads and generation system schedules have been estimated based on the information obtained from the system monitoring the energy consumption. Envelope and system retrofit have been considered.
Energy Modeling with Nonlinear-Autoregressive Exogenous Neural Network
Authors: Syed Asad Hussain , Richard Kwok Kit Yuen , Eric Wai Ming Lee 
Published: August 2019

The model-based predictive control (MPC) is considered to be an effective tool for optimal control of building heating, ventilation, and air-conditioning (HVAC) systems. MPC need to update the operating set points of the local control loops that have a significant influence on the energy performance of the system. Performance of MPC relies on the accuracy of the system performance model. There are two commonly used modeling approach – conventional or analytical approach that is the way of process modeling for some time, but it tends to increase the online computational load as it requires a full mathematical description of the real system. Furthermore, such techniques rely on different simplifying assumptions that limit the accuracy of the performance model. A second commonly used technique is the data-driven approach. The neural network (NN) is the most potent data-driven approach. NN can accurately model complex nonlinear systems without even knowing the structure of the system and it also addresses the problem of the online computational load since the computational load moves to the offline training step.
In order to set up neural network model-based predictive control (NNMPC), it is important to build a reliable energy model of HVAC system that can be used to perform multi-step-ahead prediction of system energy performance. In this paper, the energy modeling of the chiller plant is conducted. Data for the training of chiller plant energy model is generated from HVAC testbed build in TRNSYS simulation environment. The nonlinear-autoregressive neural network with exogenous input (NARX) is used to model the energy performance of the chiller plant. The NARX is a powerful method for forecasting of time series data and dynamic control problems. NARX model is first trained in the open-loop form with the actual output instead of feedback, using back-propagation with the Levenberg-Marquardt method; this model can be used to perform only one-step-ahead prediction. Open-loop NARX model is transformed into a closed-loop form, by connecting the internal feedback, i.e. actual output is replaced by predicted output, to perform multi-step-ahead prediction (for predictive control).
Comparative analysis of developed NARX-based chiller model is carried out with respect to process data from testbed, which demonstrated the good accuracy of the NARX-based chiller model.
Vulnerabilities and resilience in Danish housing stock: A comparative study of architectural answers to climate change in Danish housing in relation to other oceanic climates
Authors: Poulsen Rydborg Mikkel , Lauring Michael , Brunsgaard Camilla 
Published: August 2019

Climate change will affect the same climate zones relatively similarly. When considering how to design residential architecture for future climates it is therefore relevant to understand how residential architecture can adapt within the specific climate zone.
Denmark is placed within the oceanic climate zone and shares many of the same problems that countries in similar climates do. However, the architectural responses have developed radically different. Denmark has been building heating efficient housing for the last decade, which have lately caused increased overheating problems and surging energy demands for cooling.
This paper compares the architecture of different oceanic zones with Danish architecture. The strategies for adapting to climate change represents a broad variety.
Western European tradition has itself created varied methods for coping with the climatic struggles their societies meet. Danish architecture has for centuries been focused on heavy robust constructions that would withstand the large amount of precipitation and wind that is predominant in the country. In Holland flood danger has been a constant threat to society, which has led both to defensive and reactive measures in the form of dykes and amphibious housing. On the other side of the globe, New Zealand’s traditional architecture has adapted to similar problems but with a much lighter construction, leading to architecture that is resilient to lateral forces like wind and earthquakes. While lacking the thermal properties of northern European houses the New Zealand homes show a remarkable flexibility and mobility through simple timber-frame constructions.
The vulnerabilities in the Danish building stock is due to an unwillingness to invest in adaptive measures. It might be necessary to integrate a flexible building style to future sustainable housing and build up a different expectation for how a house is used. In the face of climate change, architecture need to be adapted to the problems apparent on the building site and draw on experiences from other cultures that might have faced similar problems in the past. Danish architects might likewise use the non-rocky ground for water retention through planting and landscaping strategies in relation to architecture.
Experimental study of radiator, underfloor, ceiling and air heater systems heat emission performance in TUT nZEB test facility
Authors: Võsa Karl-Villem , Ferrantelli Andrea , Kurnitski Jarek 
Published: August 2019

This paper reports the results of different heat emitter system measurements, which were carried out at the nZEB test facility near Tallinn University of Technology in early 2018. Radiators, underfloor heating, air heaters and radiant ceiling panels are studied as coupled with different control schemes ranging from ON-OFF to PI-type control. The objective is to assess and quantify the control accuracy and thermal comfort parameters among different configurations.
Scheduled heating dummies are used to simulate internal heat gains within the otherwise unoccupied test rooms. Along with outdoor temperature variation, the heating demand is therefore constantly changing and the control systems are continuously adjusting the heat output to maintain the desired indoor air temperatures. Control accuracy is then determined from the temperature deviations against this set value. Air stratification within the room is assessed with vertical temperature gradient calculations from measured air temperatures at different heights. The operative temperature at the point of expected occupancy is calculated from surrounding air and enclosing surface temperatures.
The quantified results provide a comprehensive comparison between the different system configurations, enabling further energy simulations in related software packages since these parameters directly influence the energy usage within a system.
Hypothesis for a more efficient and sustainable development of a district heating in Padova, integrating renewable energies and existing generation plant
Authors: Carnieletto Laura , Graci Samantha , De Carli Michele 
Published: August 2019

The present paper shows the background analysis to develop the optimization strategy of a neighborhood heating network sited in Padua, including it in a wider project of district renovation. The case study accounts several different end users: scholastic and offices buildings, a social housing residence and residential buildings.
The analysis starts from a systematic assessment of the buildings, evaluating the need of refurbishment of the envelope and of the distribution system. Further analysis focuses on the optimization of the existing heat generation system, integrating three condensing boilers, with an air to water heat pump and a ground source heat pump, which work more efficiently during base-load periods. The management of the district heating network have been investigated using the dynamic simulation tool TRNSYS, the control strategy of the delivery temperature has been tested based on the outside temperature and verifying to satisfy comfort conditions inside the buildings.
A sustainable solution is the recovery and drainage of rainwater, that can be reused for the toilets’ flushing. Therefore, the project solution identified aims at a more rational use of energy sources, which is the simplest and cheapest way to proceed on the decarbonization path that is a mid-term target for the Padua administration.
The Effect of Zinc Supplementation on Serum Leptin Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Khorshidi Masoud , Zarezadeh Meysam , Sadeghi Alireza , Teymouri Alireza , Emami Mohammad Reza , Kord-Varkaneh Hamed , Aryaeian Naheed , Rahmani Jamal , Mousavi Seyed Mohammad 
Published: August 2019

AbstractRecently, obesity has become a common worldwide concern. Leptin, as an adipocytokine, plays a major role in the etiology of obesity. Prior studies have demonstrated that zinc potentially affects serum leptin levels. However, clinical trials carried out in this regard are not consistent. Therefore, current meta-analysis was conducted to ascertain the actual effect of zinc supplementation on serum leptin levels in adults. Databases of PubMed, SCOPUS, and Google Scholar were methodically searched to identify relevant articles up to April 2018. Clinical trials that examined the effect of zinc supplementation on serum leptin concentrations as outcome variables in human adults were included. The mean difference (SD) of leptin changes in the intervention and placebo groups were used to calculate the overall effect size. Totally, 663 articles were identified, of which 6 studies were eligible randomized controlled trials (RCTs) with 7 treatment arms. The analysis suggested that zinc supplementation exerts no significant effect on overall serum leptin (WMD: 0.74 ng/ml; 95% CI: −1.39 to 2.87, p=0.49). Nevertheless, sex and duration of intervention seemed to impact the extent of zinc’s influence. In trials with female subjects, zinc consumption led to a significant decrease in serum leptin level (WMD: −1.93 ng/ml; 95% CI: −3.72 to −0.14, p=0.03) as well as trials that lasted for more than 6 weeks (WMD: −1.71 ng/ml; 95% CI: −3.07 to −0.35, p=0.01), in comparison to the control group. Zinc supplementation did not significantly improve leptin concentrations, but it may result in a decreased circulating leptin level in studies with a duration of more than 6 weeks especially among females.
Eine seltene kutane Manifestation eines systemischen B-Zell-Lymphoms unter dem klinischen Bild einer seltenen Infektionserkrankung
Authors: Konschake W. , Arnold A. , Daeschlein G. , Jünger M. , Lutze S. 
Published: August 2019

ZusammenfassungDargestellt wird der seltene Fall eines diffus großzelligen B-Zell-Lymphoms unter dem klinischen Verdacht einer kutanen Anthrax-Infektion. Bei Aufnahme präsentierte der 82-jährige Patient an der Stirn rechtsseitig oberhalb der Augenbraue eine ca. 3,5 cm messende ulzerierte Plaque mit zentral festhaftender schwarzer Nekrose und erhabenem livid-erythematösen Randwall. Wir sahen im Verlauf des stationären Aufenthaltes eine fulminante AZ-Verschlechterung des Patienten mit rezidivierenden Fieberschüben bis 40,0 °C und plötzlich disseminierter Aussaat neuer kutaner Herde ähnlich der Morphe der primären Läsion. In der CT zeigten sich multiple pulmonale und hepatische Rundherde sowie einzelne in den Nieren sowie in der rechten Nebenniere. In der Biopsie eines Leberrundherdes und in einer Hautbiopsie wurde die Diagnose eines diffus großzelligen B-Zell-Lymphoms vom ABC-Subtyp gesichert. Bei rezidivierenden Fieberschüben über 39 °C unter eskalierter Antibiose sowie persistierender nicht invasiver Beatmung wurde der Patient im Verlauf auf eine Intensivstation verlegt und verstarb nach 6-wöchiger Krankheitsdauer. Die Autoren schlussfolgern, dass bei sich extrem fulminant darstellenden Krankheitsverläufen, die klinisch einer dermatologischen Infektionserkrankung entsprechen können, jedoch unkontrollierbar unter antimikrobieller Therapie verlaufen, immer an die kutane Manifestation eines systemischen Lymphoms gedacht werden sollte. Hier können auch die primär der Infektionserkrankung zugeordnete B-Symptomatik und die elevierten Akute-Phase-Proteine auftreten. Lymphom-Manifestationen erscheinen an der Haut häufig unspezifisch mit ekzematöser, lichenoider oder pruriginös-nodulärer Morphe. Der Verlauf machte die Einordnung der Dignität der Erkrankung in unserem Fall dann möglich.
Rationale Diagnostik chronisch-entzündlicher Darmerkrankungen
Authors: Lügering Andreas 
Published: August 2019

ZUSAMMENFASSUNGSicherung der Diagnose und Objektivierung des entzündlichen Schadens chronisch-entzündlicher Darmerkrankungen sind Kernelemente bei Erstdiagnose und für die Verlaufsbeurteilung. Neben dem Goldstandard der Endoskopie nehmen konsequent wiederholbare, nicht-invasive Verfahren wie das fäkale Calprotectin und der Darmultraschall zentrale Rollen ein, um das Therapieergebnis langfristig zu optimieren, Komplikationen zu verhindern und teils erhebliche Kosten sinnvoll einzusetzen.
Patientensicherheit in der Therapie der chronisch-entzündlichen Darmerkrankungen
Authors: Bokemeyer Arne , Bettenworth Dominik 
Published: August 2019

ZUSAMMENFASSUNGDer Phänotyp chronisch-entzündlicher Darmerkrankungen zeigt eine hohe Heterogenität. Bei Patienten mit steroidabhängigem/-refraktärem Verlauf oder bei Vorliegen von klinischen Prädiktoren für einen komplizierten Krankheitsverlauf, stellen immunsuppressive und/oder immunmodulierende Substanzen wertvolle Therapieoptionen dar. Um das Auftreten potenzieller Nebenwirkungen dieser Therapien zu minimieren, sind vor Therapiebeginn eine Reihe von Maßnahmen ratsam. So sollte neben einer dezidierten Anamnese inklusive Erhebung des Impfstatus, ein laborchemisches Screening auf infektiologische Erkrankungen sowie ergänzend eine bildgebende Umfelddiagnostik erfolgen. Weiterhin bedarf es auch nach begonnener immunsuppressiver/immunmodulierender Therapie regelmäßiger Kontrollen, um medikamentös-bedingte Nebenwirkungen frühzeitig zu erkennen. Unter adäquater Vorbereitung und Surveillance einer immunsuppressiven Behandlung überwiegt der therapeutische Nutzen klar dem potenziellen Risiko für medikamentös-bedingte Nebenwirkungen.
Durch malignes Melanom ein zum damaligen Zeitpunkt lebensbedrohliches Phäochromozytom entdeckt – Glück im Unglück: 14 Jahre Rezidivfreiheit
Authors: Vavouli M. , Shab C. 
Published: August 2019

ZusammenfassungDas Phäochromozytom ist ein seltener Tumor, der in den meisten Fällen zu spät entdeckt wird. Oft handelt es sich hierbei um einen Zufallsbefund. Wir berichten über einen Fall eines malignen Melanoms, das durch sein Staging geholfen hat, ein Phäochromozytom rechtzeitig zu entdecken. In diesem Fall führte das maligne Melanom glücklicherweise zur frühzeitigen Phäochromozytom-Diagnose mit 14 Jahren Überleben ohne Rückfall.
Audiology Private Practice: What Students Should Consider
Authors: Kassa Mary 
Published: August 2019

AbstractStudents who have graduated from a Doctor of Audiology program are qualified to practice as audiologists as determined by university standards, national examination, and state licensure; however, being qualified to practice audiology does not necessarily mean a person is ready to open a private practice. Students may have had a few business or clinic management courses and may have had the opportunity to rotate through private practices; however, these few experiences would not sufficiently prepare them for the realities of owning and operating a business. This article will describe the attributes of an entrepreneur as well as some of the important issues students may wish to consider prior to taking on the responsibility of being the owner of an audiology private practice.
Resale Product and Accessory Opportunities for Audiology Practices
Authors: Bankaitis Smith A. U. 
Published: August 2019

AbstractPatients need and/or want access to any number of products, including consumables and durable goods, and accessories as part of their audiology care. Audiologists have an opportunity to offer products and accessories for resale from their clinical office. Several methods for reselling items to established patients including an overview of an ecommerce approach successfully implemented by several individual audiology private practices will be reviewed. Upon completion, readers will be familiar with the general steps for incorporating an e-shop within an existing business Web site. Additionally, insights as to effective tactics for generating e-shop revenue will be shared.
Head Injury: A Rare Cause of Bilateral Internuclear Ophthalmoplegia
Authors: Swain Srikant Kumar , Mohanty Sureswar , Panda Adya Kinkar 
Published: August 2019

AbstractRare case of bilateral internuclear ophthalmoplegia (INO) following head injury in 25-year-old male is being reported. The site of the lesion in the mid-brain as detected in the magnetic resonance imaging (MRI) correlates well with the clinical presentation. The patient recovered on conservative treatment with a course of dexamethasone (for brainstem contusion).