bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Iconic Logic of Peirce's Graphs
Authors: Shin Sun-Joo 
Published: December 2018

A case study of multimodal systems and a new interpretation of Charles S. Peirce's theory of reasoning and signs based on an analysis of his system of Existential Graphs.
At the dawn of modern logic, Charles S. Peirce invented two types of logical systems, one symbolic and the other graphical. In this book Sun-Joo Shin explores the philosophical roots of the birth of Peirce's Existential Graphs in his theory of representation and logical notation. Shin demonstrates that Peirce is the first philosopher to lay a solid philosophical foundation for multimodal representation systems.
Shin analyzes Peirce's well-known, but much-criticized nonsymbolic representation system. She presents a new approach to his graphical system based on her discovery of its unique nature and on a reconstruction of Peirce's theory of representation. By seeking to understand graphical systems on their own terms, she uncovers the reasons why graphical systems, and Existential Graphs in particular, have been underappreciated among logicians. Drawing on perspectives from the philosophy of mind, cognitive science, logic, and computer science, Shin provides evidence for a genuinely interdisciplinary project on multimodal reasoning.
Bradford Books imprint
Natural Ethical Facts
Authors: Casebeer William D. 
Published: December 2018

In Natural Ethical Facts William Casebeer argues that we can articulate a fully naturalized ethical theory using concepts from evolutionary biology and cognitive science, and that we can study moral cognition just as we study other forms of cognition. His goal is to show that we have "softly fixed" human natures, that these natures are evolved, and that our lives go well or badly depending on how we satisfy the functional demands of these natures. Natural Ethical Facts is a comprehensive examination of what a plausible moral science would look like. Casebeer begins by discussing the nature of ethics and the possible relationship between science and ethics. He then addresses David Hume's naturalistic fallacy and G. E. Moore's open-question argument, drawing on the work of John Dewey and W. V. O. Quine. He then proposes a functional account of ethics, offering corresponding biological and moral descriptions. Discussing in detail the neural correlates of moral cognition, he argues that neural networks can be used to model ethical function. He then discusses the impact his views of moral epistemology and ontology will have on traditional ethical theory and moral education, concluding that there is room for other moral theories as long as they take into consideration the functional aspect of ethics; the pragmatic neo-Aristotelian virtue theory he proposes thus serves as a moral "big tent." Finally, he addresses objections to ethical naturalism that may arise, and calls for a reconciliation of the sciences and the humanities. "Living well," Casebeer writes, "depends upon reweaving our ethical theories into the warp and woof of our scientific heritage, attending to the myriad consequences such a project will have for the way we live our lives and the manner in which we structure our collective moral institutions."
Bradford Books imprint
Looking Within
Authors: Blizzard Deborah 
Published: December 2018

An ethnographic study of fetoscopy that considers both the broader cultural context of this high-risk obstetrical procedure and the patient's individual experience.
In Looking Within, Deborah Blizzard examines the high-risk in utero surgery known as fetoscopy, considering it as both cutting-edge medical technology and as a sociocultural construction of patients, their social networks, and medical providers. She looks at the way individual experiences shape these procedures and how fetoscopy affects individuals (both patients and providers) on a personal, emotional level. Based on an eleven-month ethnographic study of the fetoscopy practice at a community-based hospital and further interviews with former patients, Looking Within offers a vivid picture of the sometimes conflicted, often desperate, and always emotional lives of those undergoing fetoscopy, and challenges current assumptions about normal and appropriate pregnancy experiences. To convey the complex reality of fetoscopy, Blizzard draws from the experiences of the real patients she interviewed for the book to present the fictional case of Melinda and Joe, taking them through the entire process, from diagnosis to decision to outcome. She then discusses the emergence of fetoscopy as an accepted form of high-risk obstetrical care, how fetoscopy programs are established at hospitals, and why otherwise healthy women consent to surgery. Blizzard examines the use of fetoscopy in single-fetus and in twin pregnancies, looking at how religion, culture, society, and medical science inform any understanding of who or what is in utero (a baby? a tumor? a mass?). She also discusses definitions of loss and success, and the narratives patients and their social networks construct to make sense of them. Looking Within will help physicians and nurses improve the development and delivery of fetoscopy procedures, help patients understand this new technology, and help scholars evaluate fetoscopy's bioethical, social, and cultural implications.
The Microsoft Antitrust Cases
Authors: Gavil Andrew I. , First Harry 
Published: December 2018

A comprehensive account of the decades-long, multiple antitrust actions against Microsoft and an assessment of the effectiveness of antitrust law in the digital age.
For more than two decades, the U.S. Department of Justice, various states, the European Commission, and many private litigants pursued antitrust actions against the tech giant Microsoft. In investigating and prosecuting Microsoft, federal and state prosecutors were playing their traditional role of reining in a corporate power intent on eliminating competition. Seen from another perspective, however, the government's prosecution of Microsoft—in which it deployed the century-old Sherman Antitrust Act in the volatile and evolving global business environment of the digital era—was unprecedented.
In this book, two experts on competition policy offer a comprehensive account of the multiple antitrust actions against Microsoft—from beginning to end—and an assessment of the effectiveness of antitrust law in the twenty-first century. Gavil and First describe in detail the cases that the Department of Justice and the states initiated in 1998, accusing Microsoft of obstructing browser competition and perpetuating its Windows monopoly. They cover the private litigation that followed, and the European Commission cases decided in 2004 and 2009. They also consider broader issues of competition policy in the age of globalization, addressing the adequacy of today's antitrust laws, their enforcement by multiple parties around the world, and the difficulty of obtaining effective remedies—all lessons learned from the Microsoft cases.
Midbrain Mutiny
Authors: Ross Don , Sharp Carla , Vuchinich Rudy E. , Spurrett David 
Published: December 2018

An analysis of how economic theories can be used to understand disordered and pathological gambling that calls on empirical evidence about behavior and the brain and argues that addictive gambling is the basic form of all addiction.
The explanatory power of economic theory is tested by the phenomenon of irrational consumption, examples of which include such addictive behaviors as disordered and pathological gambling. Midbrain Mutiny examines different economic models of disordered gambling, using the frameworks of neuroeconomics (which analyzes decision making in the brain) and picoeconomics (which analyzes patterns of consumption behavior), and drawing on empirical evidence about behavior and the brain.
The book describes addiction in neuroeconomic terms as chronic disruption of the balance between the midbrain dopamine system and the prefrontal and frontal serotonergic system, and reviews recent evidence from trials testing the effectiveness of antiaddiction drugs. The authors argue that the best way to understand disordered and addictive gambling is with a hybrid picoeconomic-neuroeconomic model.
Bradford Books imprint
Quest to Learn
Authors: Salen Tekinbaş Katie , Torres Robert , Wolozin Loretta , Rufo-Tepper Rebecca , Shapiro Arana 
Published: December 2018

The design for Quest to Learn, an innovative school in New York City that offers a “game-like” approach to learning.
Quest to Learn, an innovative school for grades 6 to 12 in New York City, grew out of the idea that gaming and game design offer a promising new paradigm for curriculum and learning. The designers of Quest to Learn developed an approach to learning that draws from what games do best: drop kids into inquiry-based, complex problem spaces that are built to help players understand how they are doing, what they need to work on, and where to go next. Content is not treated as dry information but as a living resource; students are encouraged to interact with the larger world in ways that feel relevant, exciting, and empowering. Quest to Learn opened in the fall of 2009 with 76 sixth graders. In their first semester, these students learned—among other things—to convert fractions into decimals in order to break a piece of code found in a library book; to use atlases and read maps to create a location guide for a reality television series; and to create video tutorials for a hapless group of fictional inventors. This research and development document outlines the learning framework for the school, making the original design available to others in the field. Elements in development include a detailed curriculum map, a budget, and samples of student and teacher handbooks.
Politics of Urban Runoff
Authors: Karvonen Andrew 
Published: December 2018

A study of urban stormwater runoff that explores the relationships among nature, technology, and society in cities.
When rain falls on the city, it creates urban runoff that cause flooding, erosion, and water pollution. Municipal engineers manage a complex network of technical and natural systems to treat and remove these temporary water flows from cities as quickly as possible. Urban runoff is frequently discussed in terms of technical expertise and environmental management, but it encompasses a multitude of such nontechnical issues as land use, quality of life, governance, aesthetics, and community identity, and is central to the larger debates on creating more sustainable and livable cities. In this book, Andrew Karvonen uses urban runoff as a lens to view the relationships among nature, technology, and society. Offering theoretical insights from urban environmental history, human geography, landscape and ecological planning, and science and technology studies as well as empirical evidence from case studies, Karvonen proposes a new relational politics of urban nature.
After describing the evolution of urban runoff practices, Karvonen analyzes the urban runoff activities in Austin and Seattle—two cities known for their highly contested public debates over runoff issues and exemplary storm water management practices. The Austin case study highlights the tensions among urban development, property rights, land use planning, and citizen activism; the Seattle case study explores the city's long-standing reputation for being in harmony with nature. Drawing on these accounts, Karvonen suggests a new relational politics of urban nature that is situated, inclusive, and action-oriented to address the tensions among nature, technology, and society.
Game After
Authors: Guins Raiford 
Published: December 2018

A cultural study of video game afterlife, whether as emulation or artifact, in an archival box or at the bottom of a landfill.
We purchase video games to play them, not to save them. What happens to video games when they are out of date, broken, nonfunctional, or obsolete? Should a game be considered an “ex-game” if it exists only as emulation, as an artifact in museum displays, in an archival box, or at the bottom of a landfill? In Game After, Raiford Guins focuses on video games not as hermetically sealed within time capsules of the past but on their material remains: how and where video games persist in the present. Guins meticulously investigates the complex life cycles of video games, to show how their meanings, uses, and values shift in an afterlife of disposal, ruins and remains, museums, archives, and private collections.
Guins looks closely at video games as museum objects, discussing the recontextualization of the Pong and Brown Box prototypes and engaging with curatorial and archival practices across a range of cultural institutions; aging coin-op arcade cabinets; the documentation role of game cartridge artwork and packaging; the journey of a game from flawed product to trash to memorialized relic, as seen in the history of Atari's infamous E.T. The Extra-Terrestrial; and conservation, restoration, and re-creation stories told by experts including Van Burnham, Gene Lewin, and Peter Takacs.
The afterlife of video games—whether behind glass in display cases or recreated as an iPad app—offers a new way to explore the diverse topography of game history.
Ethics, Sexual Orientation, and Choices about Children
Authors: Murphy Timothy F. 
Published: December 2018

A critical review of the debate over the still-hypothetical possibility of prenatal intervention by parents to select the sexual orientation of their children.
Parents routinely turn to prenatal testing to screen for genetic or chromosomal disorders or to learn their child's sex. What if they could use similar prenatal interventions to learn (or change) their child's sexual orientation? Bioethicists have debated the moral implications of this still-hypothetical possibility for several decades. Some commentators fear that any scientific efforts to understand the origins of homosexuality could mean the end of gay and lesbian people, if parents shy away from having homosexual children. Others defend parents' rights to choose the traits of their children in general and see no reason to treat sexual orientation differently. In this book, Timothy Murphy traces the controversy over prenatal selection of sexual orientation, offering a critical review of the literature and presenting his own argument in favor of parents' reproductive liberty.
Arguing against commentators who want to restrict the scientific study of sexual orientation or technologies that emerge from that study, Murphy proposes a defense of parents' right to choose. This, he argues, is the only view that helps protect children from hurtful family environments, that is consistent with the increasing powers of prenatal interventions, and that respects human futures as something other than accidents of the genetic lottery.
A Fragmented Continent
Authors: Edwards Guy , Roberts J. Timmons 
Published: December 2018

How Latin American countries became leading voices and innovators on addressing climate change—and what threatens their leadership.
Latin American countries have increased their influence at the United Nations climate change negotiations and offered potential solutions on coping with global warming. But in the face of competing priorities, sometimes these climate policies are jettisoned, undermined, or simply ignored.
A Fragmented Continent focuses on Latin America's three major blocs at the U.N. climate negotiations and how they attempt to balance climate action with building prosperity. Brazil has reduced its deforestation but continues its drive for economic growth and global recognition. A leftist group led by Venezuela, Bolivia, and Ecuador decries the injustice of climate change but is highly dependent on the export of fossil fuels. A new group, including Chile, Costa Rica, and Peru and supported by Mexico, offers sharp reductions in their carbon emissions in return for greater action by others; these countries now have to deliver on their promises. Weaving together issues of politics and economy, trade, foreign policy, civil society, and environmental protection, A Fragmented Continent offers a long-missing perspective on one of this century's greatest challenges and neglected regions.
Collaborative Media
Authors: Löwgren Jonas , Reimer Bo 
Published: December 2018

A thorough analysis of contemporary digital media practices, showing how people increasingly not only consume but also produce and even design media.
With many new forms of digital media–including such popular social media as Facebook, Twitter, and Flickr—the people formerly known as the audience no longer only consume but also produce and even design media. Jonas Löwgren and Bo Reimer term this phenomenon collaborative media, and in this book they investigate the qualities and characteristics of these forms of media in terms of what they enable people to do. They do so through an interdisciplinary research approach that combines the social sciences and humanities traditions of empirical and theoretical work with practice-based, design-oriented interventions.
Löwgren and Reimer offer analysis and a series of illuminating case studies—examples of projects in collaborative media that range from small multidisciplinary research experiments to commercial projects used by millions of people. Löwgren and Reimer discuss the case studies at three levels of analysis: society and the role of collaborative media in societal change; institutions and the relationship of collaborative media with established media structures; and tribes, the nurturing of small communities within a large technical infrastructure. They conclude by advocating an interventionist turn within social analysis and media design.
Differential regulation of brain‐derived neurotrophic factor (BDNF) expression in sensory neuron axons by miRNA‐206
Authors: Shrestha Shiva , Phay Monichan , Kim Hak Hee , Pouladvand Pedram , Lee Seung Joon , Yoo Soonmoon 
Published: December 2018

Distinct subcellular localization and subsequent translational control of 3′ UTR variants of mRNA encoding brain‐derived neurotrophic factor (BDNF) are critical for the development and plasticity of neurons. Although the processes that lead to preferential localization of BDNF have been well studied, it is still not clear how neurons ensure differential BDNF production in a spatial‐specific manner. Here, we identified that microRNA (miRNA)‐206 has the potential to specifically regulate BDNF with a long 3′ UTR without affecting its short 3′ UTR counterpart. Overexpression of miRNA‐206 in sensory neurons resulted in a 30% and 45% reduction of BDNF protein expression in the cell bodies and axons, respectively. The work described in the present study indicates that miRNAs can differentially and specifically regulate the expression of transcript variants with different localization patterns.
A novel and innovative device to retract rectum during radiation therapy of pelvic tumors
Authors: Parsai E. Ishmael , Jahadakbar Ahmadreza , Lavvafi Hossein , Elahinia Mohammad 
Published: December 2018

AbstractAn effective radiotherapy treatment entails maximizing radiation dose to the tumor while sparing the surrounding and normal tissues. With the advent of SBRT with extreme hypo‐fractionation in treating tumors including prostate where ablative dose is delivered in smaller number of fractions, rectum remains a dose‐limiting organ and at the risk of rectal toxicity or secondary cancer. The same limitation of rectal toxicity exists for high‐dose rate (HDR) treatments of cervical, endometrial, or prostate cancer when creating even a short distance between the anterior rectal wall and field of radiation is ideal in delivering ablative dose to the target. An effective solution to such problem is to physically displace rectum as the organ at risk. This research presents an organ retractor device that is designed to displace the rectum away from the path of radiation beam employing a Nitinol shape memory alloy that is designed for displacing the rectum upon actuation. A control system regulates the motion in a reproducible and safe manner by creating the desirable shape in moving the anterior rectal wall. The study finds the novel organ retractor device to be a promising tool that can be applied in a clinical setting for minimizing dose to the rectum during treatment of pelvic tumors, and creating the potential to deliver an ablative dose to tumor volume or to escalate the dose when needed.
Mild malformations of cortical development in sleep‐related hypermotor epilepsy due to KCNT1 mutations
Authors: Rubboli Guido , Plazzi Giuseppe , Picard Fabienne , Nobili Lino , Hirsch Edouard , Chelly Jamel , Prayson Richard A. , Boutonnat Jean , Bramerio Manuela , Kahane Philippe , Dibbens Leanne M. , Gardella Elena , Baulac Stéphanie , Møller Rikke S. 
Published: December 2018

AbstractMutations in the sodium‐activated potassium channel gene KCNT1 have been associated with nonlesional sleep‐related hypermotor epilepsy (SHE). We report the co‐occurrence of mild malformation of cortical development (mMCD) and KCNT1 mutations in four patients with SHE. Focal cortical dysplasia type I was neuropathologically diagnosed after epilepsy surgery in three unrelated MRI‐negative patients, periventricular nodular heterotopia was detected in one patient by MRI. Our findings suggest that KCNT1 epileptogenicity may result not only from dysregulated excitability by controlling Na+K+ transport, but also from mMCD. Therefore, pathogenic variants in KCNT1 may encompass both lesional and nonlesional epilepsies.
Regional surname affinity: A spatial network approach
Authors: Shi Yongbin , Li Le , Wang Yougui , Chen Jiawei , Yuan Yida , Stanley H. E. 
Published: December 2018

AbstractObjectiveWe investigate surname affinities among areas of modern‐day China, by constructing a spatial network, and making community detection. It reports a geographical genealogy of the Chinese population that is result of population origins, historical migrations, and societal evolutions.Materials and methodsWe acquire data from the census records supplied by China's National Citizen Identity Information System, including the surname and regional information of 1.28 billion registered Chinese citizens. We propose a multilayer minimum spanning tree (MMST) to construct a spatial network based on the matrix of isonymic distances, which is often used to characterize the dissimilarity of surname structure among areas. We use the fast unfolding algorithm to detect network communities.ResultsWe obtain a 10‐layer MMST network of 362 prefecture nodes and 3,610 edges derived from the matrix of the Euclidean distances among these areas. These prefectures are divided into eight groups in the spatial network via community detection. We measure the partition by comparing the inter‐distances and intra‐distances of the communities and obtain meaningful regional ethnicity classification.DiscussionThe visualization of the resulting communities on the map indicates that the prefectures in the same community are usually geographically adjacent. The formation of this partition is influenced by geographical factors, historic migrations, trade and economic factors, as well as isolation of culture and language. The MMST algorithm proves to be effective in geo‐genealogy and ethnicity classification for it retains essential information about surname affinity and highlights the geographical consanguinity of the population.