bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elicitation of Health-related Quality-of-life Concepts Associated with Overactive Bladder: A Qualitative Study
Authors: Hawken Natalia , Hakimi Zalmai , Aballéa Samuel , Nazir Jameel , O. Odeyemi Isaac A. , Toumi Mondher 
Published: October 2019

Background: Overactive bladder (OAB) is a symptom-defined disorder. A range of instruments are available for assessing OAB symptom bother, urinary urgency and the effects of symptoms on health-related quality of life (HRQoL), but few have been specifically designed and validated for this condition. HRQoL instruments should capture the concepts that are most relevant to patients. To our knowledge, there is no existing published conceptual framework for OAB.

Objectives: We performed a qualitative study to explore the impact of symptoms of OAB on affected patients and to develop a conceptual framework for OAB.

Methods: Patients diagnosed with OAB living in the United Kingdom were interviewed on the telephone by a trained psychologist using an interview discussion guide. Interview transcripts were analyzed thematically by two psychologists. Data collection and analysis was completed when data saturation, i.e. when little or no new information was obtained, was achieved.

Results: A total of 30 patients were interviewed. Fifteen patients (50%) had urge incontinence (i.e. OAB-wet). Interview data showed that OAB affected role functioning, sleep quality, social functioning, and emotional/mental functioning. In addition, patients often adopted non-medical coping strategies to manage their symptoms (e.g. planning activities). Factors which affected more than 50% of patients were going for a short walk, waking up at night, travelling/holidays, socializing/going out, embarrassment/shame, need to plan activities, and restriction of places visited. More patients with OAB-wet reported impairment of social and emotional/mental functioning than patients with OAB-dry. A conceptual framework for adults with OAB depicting the relationships between OAB concepts (or outcomes) was developed.

Conclusions: OAB has a profound effect on patient HRQoL and negatively affects a broad range of functions, including daily and work activities, leisure and social activities, psychological well-being, and sleep capacity. The conceptual framework emerging from this study supports the utilization of existing disease-specific HRQoL instruments, but identifies that work-related effects, which are relevant for OAB patients, are missing from currently available measures.
Est-il trop tard pour l’effondrement ?
Authors: Allard Laurence , Monnin Alexandre , Tasset Cyprien 
Published: October 2019

Cette introduction invite à décadrer et à recadrer la thématique de l’effondrement, popularisée et médiatisée par la théorie dite « collapsologie », vers le plan des acteurs, des terrains, des temporalités, et des régimes d’énonciation. Nous appelons à documenter empiriquement ce que fait l’effondrement, et ce qu’en font celles et ceux à qui cette idée « fait » quelque chose. En effet, l’effondrisme pose la question des façons de se positionner non pas uniquement par rapport à une théorie, mais également par rapport à des expériences individuelles et collectives. Le dossier vise à comprendre comment la réception de la « collapsologie » donne lieu à des jeux complexes entre désemparement et capacités d’agir. L’atterrissage sur un sol anthropocénique de plus en plus critique mérite une décisive discussion collective. L’hypothèse de cette majeure est que les expériences effondristes ont une valeur d’expérimentation à cet égard, notamment en créant un zone discursive et praxique où des cultures et des expériences politiques différentes sont amenées à se rencontrer et à collaborer.
Sur les traversées
Authors: Kandé Sylvie , Bertho Elara 
Published: October 2019

Dans cet entretien, la poétesse explore ce que signifie l’écriture de l’histoire des « sans histoires ». À travers la nouvelle qu’elle livre à Multitudes , intitulée précisément « sans histoire/s », et son recueil La quête infinie de l’autre rive (2011), l’auteur analyse le pouvoir de « considération » de la littérature, reliant les pensées de Marielle Macé avec celles d’Édouard Glissant.
Sur une nette inversion du schème de la fin des temps
Authors: Latour Bruno 
Published: October 2019

En partant de l’encyclique Laudato si’ , la contribution retrace l’originalité de la proposition du pape François. L’irruption de l’Anthropocène comme définition nouvelle de la géo-histoire a pour effet imprévu de modifier la répartition des figures de l’espace et de temps qui ont servi à recueillir la prédication évangélique dans les époques précédentes. L’Anthropocène oblige à reprendre par de nouvelles figures de l’espace et du temps, le schème de la fin du temps, renouvelant ainsi les expressions traditionnelles de l’apocalypse : c’est désormais l’immanence et non plus la transcendance qui devient la figure centrale. La question se pose de savoir si les rituels peuvent se nourrir de cette inversion pour renouveler la prédication.
Association between weight loss and clinical-pathologic factors in oncological patients in chemotherapy treatment: a longitudinal study
Authors: Pinheiro Débora Fernandes , Benincá Simone Carla , Mazur Caryna Eurich , Meira Elisângela , Wouk Jessica 
Published: October 2019

The present study aimed to evaluate the nutritional state and WL of individuals with cancer. Is a longitudinal observational study was performed with patients assisted in the oncological ambulatory. Sample was composed of 402 patients, with an average of 58.46±13.60 years old, 56.5% women and the majority elderly (51.74%). Regarding tumor localization, 12.9% were found in the head and neck, 22.6% in mamas, 10.2% in the lungs, 29.4% in the gastrointestinal tract (GI tract) and 29.4% in other body parts. A gradual fall of nutritional state in relation to BMI was observed, and the patients were advancing to malnutrition. When severe and not severe WL were correlated, a statistical difference was demonstrated regarding age, current and habitual weight, as well as the corresponding BMI (p<0.05). Overweight and obese patients presented a higher severe WL than the other group (p<0.05). However, 67.34% of patients presented WL and a following nutritional state alteration, being cancer in the GI tract with a significant difference, 37.44% (p<0.05) with severe WL (p<0.000). Patients diagnosed with cancer, especially in the GI tract, treated with chemotherapy have higher chances of WL, which trigger a reduction of survival rate, being obesity and age reliable predictors of a consequent severe WL.
YUKARIYA DOĞRU HAREKETLİLİKTE BİR İMKÂN VE SINIRLILIK OLARAK TÜRKİYE’DE MESLEK LİSELERİ: ESKİŞEHİR ÖRNEĞİ ÜZERİNE SOSYOLOJİK BİR ARAŞTIRMA
Authors: YAZGAN Çağdaş Ümit , SUĞUR Nadir 
Published: October 2019

Türkiye’de
meslek liseleri, çoğunluğu düşük gelir gruplarından gelen genç nüfusa mesleki
ve teknik beceriler kazandırarak istihdam olasılığını artıran ve yoksulluktan
kurtulma şansı tanıyan çeşitli avantajlarla ilişkilendirilebilmektedir. Bu
okullar aynı zamanda kentsel alanda genç nüfusun yukarıya doğru sosyal
hareketliliğini engelleyen bir bariyer ya da eşitsizliği kuşaktan kuşağa
aktaran bir yoksulluk tuzağı olma gibi bir takım sosyal ve ekonomik
dezavantajlara da konu olabilmektedir. Bu araştırma, avantaj ve dezavantajlar
bağlamında, öğrencilerin eğitim almakta oldukları meslek liseleri ile ilgili görüşlerini
ortaya çıkarmayı ve bu görüşleri temel sosyolojik yaklaşımlar çerçevesinde değerlendirmeyi
amaçlamaktadır.

Araştırma,
2016 Aralık-2017 Ocak aylarında Eskişehir İl Milli Eğitim Müdürlüğü’ne bağlı 7
adet mesleki ve teknik Anadolu lisesinde yürütülmüştür. Nicel veriler 12.
sınıfta eğitim gören 796 öğrenciden anket tekniği ile nitel veriler ise 9
öğretmen, 8 mezun, 8 öğrenci olmak üzere 25 kişiden yarı yapılandırılmış görüşme
tekniği ile toplanmıştır.
Öğrencilerin
çoğunluğu istihdam hızı ve kolaylığı, işgücü piyasasında tutunabilme, ön lisans
programlarına yerleşebilme imkânları bakımından meslek liselerini daha
avantajlı bulmaktadır. Araştırma kapsamındaki öğrenciler meslek liselerini
kentsel alandaki rekabete dayalı iş gücü piyasasında iş bulmanın en kolay, en
hızlı ve en ucuz yolu olarak görmektedir. Anadolu liseleri ise üniversiteye
giriş sınavlarında daha iyi puan alabilme bakımından avantajlı görülmektedir. Öğrenciler
için Anadolu liseleri, lisans düzeyindeki yükseköğretim programlarına girişi
kolaylaştırması bakımından, daha iyi bir çalışma hayatı, görece yüksek ücret,
daha iyi çalışma koşulları ve yüksek sosyal statü anlamına gelmektedir. Bulgular
bütünlüklü olarak değerlendirildiğinde, öğrencilerin çoğunluğu için meslek liselerinin
umut ve umutsuzluğun kesiştiği bir konumda yer aldığı görülmektedir.
Eosinophil Density in Common Benign and Malignant Salivary Gland Tumors with Congo Red Staining
Authors: Seifi Safoura , Azizi Zahra , Ghanghermeh Alten , Eftekharian Shahriar , Salehinejad Jahanshah , Gholinia Hemmat 
Published: October 2019

Abstract
Purpose: Eosinophils are multifunctional leukocytes with unknown mechanisms in salivary gland tumors. Some researchers associate eosinophils with tumor progression and others have proposed them as antitumoral. The present study was conducted to compare the density of eosinophils in common salivary gland tumors and its relationship with the degree of differentiation in malignant salivary gland tumors. Materials and Methods: In this present descriptive-analytical, cross-sectional study, 15 cases of pleomorphic adenoma, 15 cases of adenoid cystic carcinoma (ACC), 30 cases of mucoepidermoid carcinoma (MEC), and 5 cases of normal salivary glands were extracted. Sections were prepared of these cases for Congo red staining. The malignant salivary gland tumors were classified as high-grade and low-grade malignancies. The slides were observed under ×10, and the highest-density areas were selected and counted in ten microscopic fields under ×40. Results: The density of the eosinophils was 4.5 ± 5.6 in the pleomorphic adenoma, 16.2 ± 6.01 in the low-grade MEC, 1.05 ± 1.1 in the high-grade MEC (Grade III), and the ACC, and 0.4 ± 0.89 in the normal salivary gland. Eosinophil density was significantly higher in low-grade malignancies compared to in benign or high-grade malignant neoplasms and normal salivary gland (P < 0.001). Conclusion: This is suggested which the density of eosinophils is associated with the process of tumorigenesis and the degree of malignancy in malignant salivary gland tumors.
Hodgkin Lymphoma Presenting as Immune Thrombocytopenia
Authors: Jain Mili , Pandey Neetu , Verma Nishant , Kumar Ashutosh 
Published: October 2019

AbstractImmune thrombocytopenia (ITP) in lymphoid malignancies has been observed primarily in relation to chronic lymphoproliferative disorders. ITP in Hodgkin lymphoma (HL) is a rare presentation, most often reported at follow-up. We report a case of a 12-year-old female presenting with symptomatic thrombocytopenia at the time of diagnosis of HL. The patient had stage III B bulky disease with HL mixed cellularity subtype on histology. The patient was treated with adriamycin, bleomycin, vinblastine, and dacarbazine regime along with local radiation therapy and is in complete remission at 18 months of follow-up. The treatment of underlying lymphoma in such cases resolves thrombocytopenia.
Assessment of Chemotherapy-Induced Febrile Neutropenia in Cancer Patients
Authors: Philip Malona Lilly , Saj Neethu , Sebastian Antony Mathew , Mateti Uday Venkat , Shetty Vijith 
Published: October 2019

Abstract
Purpose: Chemotherapy-induced febrile neutropenia (CIFN) is an adverse drug reaction which needs medical attention. The treatment options for the CIFN are mandatory to improve treatment outcomes and quality of life. Methods: A prospective observational study was conducted in the in-patients and out-patients of oncology department who received chemotherapy from October 2016 to March 2017. The information such as demographics (age, gender, and comorbidities), complaints on admission, hematological investigations (neutrophil counts, platelet counts, hemoglobin levels, erythrocyte sedimentation rate, and white blood cells), type of tumor, stage of cancer, prophylaxis, cycle of antineoplastic chemotherapy that cause febrile neutropenia, treatment history, and outcome data were obtained from the patient's clinical record. The Multinational Association for Supportive Care in Cancer score and Absolute Neutrophil Count grading was used to predict the patient's risk of developing CIFN. Results: Out of 200 patients, 19 patients developed 22 episodes of CIFN. The overall occurrence of CIFN during the study was 9.5%. The higher incidence of CIFN has been observed among male gender (57.89%), stage III patients (42.10%), solid tumor (73.68%), and double chemotherapy regimen (59.1%). The higher incidence of CIFN was developed in I cycle (36.36%) followed by II cycle (22.72%) and VI cycle (18.18%). Conclusions: The incidence of CIFN during the study was 9.5%. In the 19 chemotherapy-induced FN patients, there has no significant effect of prophylaxis to prevent the febrile neutropenia.
Tracking down global NH3 point sources with wind-adjusted superresolution
Authors: Clarisse Lieven , Van Damme Martin , Clerbaux Cathy , Coheur Pierre-François 
Published: October 2019

Abstract. As a precursor of atmospheric aerosols, ammonia (NH3) is one of the primary gaseous air pollutants. Given its short atmospheric lifetime, ambient NH3 concentrations are dominated by local sources. In a recent study, Van Damme et al. (2018) have highlighted the importance of NH3 point sources, especially those associated with feedlots and industrial ammonia production. Their emissions were shown to be largely underestimated in bottom-up emission inventories. The discovery was made possible thanks to the use of oversampling techniques applied to 9 years of global daily IASI NH3 satellite measurements. Oversampling allows one to increase the spatial resolution of averaged satellite data beyond what the satellites natively offer. Here we apply for the first time superresolution techniques, which are commonplace in many fields that rely on imaging, to measurements of an atmospheric sounder, whose images consist of just single pixels. We demonstrate the principle on synthetic data and on IASI measurements of a surface parameter. Superresolution is a priori less suitable to be applied on measurements of variable atmospheric constituents, in particular those affected by transport. However, by first applying the wind-rotation technique, which was introduced in the study of other primary pollutants, superresolution becomes highly effective in mapping NH3 at a very high spatial resolution. We show that plume transport can be revealed in greater detail than what was previously thought to be possible. Next, using this wind-adjusted superresolution technique, we introduce a new type of NH3 map that allows tracking down point sources more easily than the regular oversampled average. On a subset of known emitters, the source could be located within a median distance of 1.5 km. We subsequently present a new global point-source catalog consisting of more than 500 localized and categorized point sources. Compared to our previous catalog, the number of identified sources more than doubled. In addition, we refined the classification of industries into five categories – fertilizer, coking, soda ash, geothermal and explosives industries – and introduced a new urban category for isolated NH3 hotspots over cities. The latter mainly consists of African megacities, as clear isolation of such urban hotspots is almost never possible elsewhere due to the presence of a diffuse background with higher concentrations. The techniques presented in this paper can most likely be exploited in the study of point sources of other short-lived atmospheric pollutants such as SO2 and NO2.
Enraciner, explorer, pénétrer le secret dans la fiction du XVIIIe siècle
Authors: Daguisé Floriane 
Published: October 2019

L’étymologie du terme « secret », issu du participe passé du verbe secernere signifiant « mettre à part », « séparer », invite à penser le secret en termes d’espace. Le Dictionnaire de Trévoux confirme son affinité avec le domaine privé en spécifiant l’usage de l’adjectif appliqué à un lieu : « Un lieu secret, c’est le privé », c’est-à-dire un espace solitaire, isolé. Au cours du xviiie siècle, les habitations, en particulier urbaines, connaissent des évolutions, selon un double mouvement de clôture et d’ouverture : l’espace devient labyrinthe, fondé sur les plis et replis architecturaux, tendu vers une dispersion illimitée, entre miniaturisation et circulation. Dans sa mise en scène récurrente de la préservation et de la surprise du secret, les fictions du xviiie siècle rendent compte des aménagements contemporains, en exploitent le potentiel dramatique et en traduisent la nature symbolique. Si la critique a bien mis en évidence l’usage libertin de l’espace, dans la gradation spatialisée du désir, il apparaît que le secret tenu caché ou mis à découvert dans les œuvres du xviiie siècle offre le spectacle du secret en une pratique spatialisée et contrôlée. L’espace n’est pas seulement un outil pour accéder au secret, mais un instrument pour séduire et contraindre, en somme pour captiver.
HL7 Terminology Management for Disease Surveillance
Authors: Roberts Emily , Jeppson Theron , Boulton Rachelle , Ridderhoff Josh 
Published: October 2019

Objective: The objective of this abstract is to illustrate how the Utah Department of Health processes a high volume of electronic data. We do this by translating what reporters send within an HL7 message into "epidemiologist" language for consumption into our disease surveillance system.Introduction: In 2013, the Utah Department of Health (UDOH) began working with hospital and reference laboratories to implement electronic laboratory reporting (ELR) of reportable communicable disease data. Laboratories utilize HL7 message structure and standard terminologies such as LOINC and SNOMED to send data to UDOH. These messages must be evaluated for validity, translated, and entered into Utah’s communicable disease surveillance system (UT-NEDSS), where they can be accessed by local and state investigators and epidemiologists. Despite the development and use of standardized terminologies, reporters may use different, outdated versions of these terminologies, may not use the appropriate codes, or may send local, home-grown terminologies. These variations cause problems when trying to interpret test results and automate data processing. UDOH has developed a two-step translation process that allows us to first standardize and clean incoming messages, and then translate them for consumption by UT-NEDSS. These processes allow us to efficiently manage several different terminologies and helps to standardize incoming data, maintain data quality, and streamline the data entry process.Methods: UDOH uses the Electronic Message Staging Area (EMSA) to receive ELR messages, manage terminologies such as LOINC and SNOMED, translate messages, and automatically enter laboratory data into UT-NEDSS. LOINCs and other terms, such as facility name, sent by reporting facilities in an HL7 message are considered child terms. All child terms are mapped to a master LOINC or term and each master LOINC or term is mapped to a specific value within UT-NEDSS. In EMSA, the rules engine used for automated processing of electronic data is set to run at the master level and these rules will determine how the message is processed. No rules are set up or run on child terms.Results: As of 09/20/2017, EMSA contains 2,613 unique child LOINCs that are mapped to 906 master LOINCs. Those 906 master LOINCs are mapped to 179 UT-NEDSS test types and 2003 child facility names are mapped to 1043 master facility namesConclusions: Mapping child terminologies from an HL7 message to a master vocabulary helps us to standardize incoming data, allows us to accept non-standard terminologies and correct reporting errors. Translating this data into a format that is understandable to epidemiologists and investigators enables UT-NEDSS to work effectively in identifying outbreaks and improving health outcomes. This framework is working for ELR and will continue to grow and accept more data and the different terminologies that come with that.
Leveraging the NSSP R Studio Server to Automate QA Monitoring and Reporting
Authors: Rock Peter J , Singleton Michael D 
Published: October 2019

Objective: The aim of this project was to develop a nimble system to both monitor and report on the quality of Kentucky emergency department syndromic surveillance (SyS) data at system-wide and facility levels.Introduction: In 2016, the CDC funded 12 states, under the Enhanced State Opioid Overdose Surveillance (ESOOS) program, to utilize SyS to increase timeliness of state data on drug overdose events. In order to operationalize the objectives of the grant, there was a need to assess and monitor the quality of Kentucky’s SyS data, with limited resources. We leveraged the NSSP’s R Studio Server to automate quality assurance (QA) monitoring and reporting to meet these objectives.Methods: Using the R Server, we pulled data from the process messages table, aggregating messages to single patient encounters. In addition to compiling the code on a powerful remote server, the server can access the process table messages relatively quickly. We developed an R Markdown report to produce a report that includes a variety of system- and facility-level metrics that highlight key indicators of system performance and data flows. By using R, we were able to create an auto-generating QA report that runs weekly and e-mails for analyst review. Quality metrics included: % completeness of chief complaint and discharge diagnosis codes (overall and by facility)[Fig 1 & Fig 2]; visit trend by day of visit (with interactive spark lines)[Fig 2]; maximum date of message created, date message arrived at NSSP server, date of visit, and total messages[Fig 3]; message arrived trend (interactive sparklines)[Fig 3]; volume and type of error messages failing to process[Fig 4]; message volume by ADT type[Fig 5]; and volume of patient class by type by day[not shown]. Our SyS analyst reviews the report and delivers it to stakeholders with general comments about ongoing and newly emerging data quality concerns.Results: The report has proven to be beneficial in ongoing QA monitoring. The report is shared weekly with key stakeholders at the Kentucky Department for Public Health, Kentucky Health Information Exchange, NSSP, and regional ESSENCE users. Findings are reviewed at monthly SyS stakeholder meetings. The report has identified numerous errors, dead feeds, and other systems changes in near real-time; leading to corrective action and general data quality enhancement. Weekly monitoring of QA has improved data feed stability and communication of identified issue with key stakeholders.Conclusions: The R Studio Server provides a nimble platform to develop, refine, and automate a QA reporting system that can lead to improved SyS data quality. In Kentucky, in addition to improving overall data quality, these weekly reports and subsequent communication have help built relationships among key stakeholders and elevated the importance of syndromic surveillance data locally. Continual monitoring of data is critical to ensure quality and therefor the validity of the data.