bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of primary and secondary delays in the effective resonance frequency of acoustically interacting microbubbles
Authors: Haghi Hossein , Kolios Michael C. 
Published: November 2024

<p>Acoustically excited microbubbles (MBs) are known to be nonlinear oscillators with complex dynamics. This has enabled their use in a wide range of applications from medicine to industry and underwater acoustics. To better utilize their potential in applications and possibly invent new ones a comprehensive understanding of their dynamics is required. In this work, we explore the effect of bubble-bubble interactions on the resonance frequency of MB suspensions. MBs oscillate in response to an external acoustic wave and since bubbles in a cluster are at different locations compared to the excitation source, they are excited at different times. In this work we refer to these delays as primary delays. Interactions between the scattered pressure fields from adjacent bubbles have also been shown to alter the dynamics of MBs that exist within clusters. These secondary waves generated by MBs reach MBs in their proximity at different times that depend on their spatial location in the cluster. Here we refer to these delays as secondary delays. Inclusion of the secondary delays modifies the class of the differential equations governing the oscillations of interacting MBs in a cluster from ordinary differential equations to neutral delay differential equations. Previous work has not considered the all the delays associated with the bubble distances when modeling the interactions between bubbles. In this work we investigate the effect of both the primary and secondary delays on the effective resonance frequency of MB clusters. It is shown that primary delays cause spreading the resonance frequency of identical MBs within a range where the closest MB to the acoustic source exhibits the lowest resonance frequency and the furthest MB resonates at the highest frequency. This range has been shown to be up to 0.12 MHz for the examples investigated in this work. The effect of secondary delays is shown to be very significant. In the absence of secondary delays, the ordinary differential equation model predicts a decrease of up to 26% in the resonance frequency of 4 identical interacting MBs as the inter-bubble distances are decreased. However, we show that inclusion of the secondary delays result in the increase of the resonance frequency of MBs if they are situated close to each other. This increase is shown to be significant and for the case of 4 identical interacting MBs we show an increase of 58% in the resonance frequency.</p>
Are we there yet? Forty years of Employment Equity - the good, the bad and the ugly
Authors: Cukier Wendy 
Published: November 2024

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<p>Canada’s Employment Equity (EE) Act from 1986 was designed to help “level the playing field” for groups that were historically discriminated against. It required federally regulated corporations and federal contractors to track and report on the proportion of “designated groups” and their strategies to advance inclusion. The designated groups were initially identified as women, Aboriginal peoples, persons with disabilities, and members of visible minorities, although the terms have been updated to “racialized people” and Indigenous peoples recognizing shifting norms. The Act also requires disclosure of policies, but reporting and monitoring of the policies is uneven."</p>
Career Satisfaction: A Look behind the Races
Authors: Yap Margaret , Cukier Wendy , Holmes Mark Robert , Hannan Charity-Ann 
Published: November 2024

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<p>Previous studies have largely focused on the career success of white employees (Heslin, 2005). Using recent survey data, this paper examines the career satisfaction levels of white/Caucasian and visible minority managerial, professional and executive employees in the information and communications technology [ICT] and financial services sectors in corporate Canada. Given that the demographic makeup of organizations in Canada is drastically changing with the aging population and the increasing participation of visible minorities in the labour force, it is crucial for managers and organizations to understand their employees’ level of career satisfaction. Studies have found that employees who are more satisfied with their careers are more engaged and thus are more likely to actively contribute to the organization’s success (Peluchette, 1993; Harter, Schmidt and Hayes, 2002). Findings from this paper showed that the average career satisfaction scores were lower for visible minority employees than for white/Caucasian employees. In addition, variations were found between white/Caucasian employees and Chinese, South Asian and Black visible minority employees. While Black employees were 13.0% less satisfied than white/Caucasian employees, Chinese employees were only 8.3% less satisfied than their white/Caucasian counterparts, and the difference between South Asian and white/Caucasian employees was found to be insignificant. Decomposition analyses show that over 58% to 82% of the difference in career of satisfaction scores, depending on the ethnic group, can be accounted for by factors included in this paper. Of the unexplained portion, most of the differences in career satisfaction between white/Caucasian and minority groups are attributable to higher returns to white/Caucasian employees’ human capital and demographic characteristics.</p>
Measuring Knowledge Translation Uptake Using Citation Metrics: A Case Study of a Pan-Canadian Network of Pharmacoepidemiology Researchers
Authors: Rothfus Melissa , Sketris Ingrid S. , Traynor Robyn , Helwig Melissa , Stewart Samuel A 
Published: November 2024

<p>Collecting citation metric data is important, as research funders are increasingly demanding impact assessment, but there is limited consensus on the most rigorous and accurate approach. We compared three sources of citation counts (Google Scholar, Web of Science, Scopus) to determine their reliability, comprehensiveness, and currency. We identified each tool’s strengths and limitations, particularly when considering team outputs. Citation counts varied, with poor overall agreement: Fleiss’ kappa, 0.075 (95% CI [0.01, 0.12]). Researchers, funders, and administrators need to understand each tool’s unique strengths and limitations and develop guidelines for use within specific contexts.</p>
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Hubungan Teknik Mencuci Wajah dengan Keberhasilan Pengobatan Acne Vulgaris di Poli Dermatologi RSUD Dr. H. Abdul Moeloek Provinsi Lampung
Authors: Fadhillah Ummul , Yuliana Dewi , Sujiah Sujiah 
Published: November 2024

ABSTRACT One of the most common skin problems is acne vuilgaris. The prevalence of acnve vulgaris worldwide in 2022 was approximaitely 80%, in Indonesia aroiund 85%, while in Lampung Province it was around 69.7%. Data from the Dermatology Polyclinic of Dr. H. Abdul Moeloek Regional iGenerval Hospital, Lampung Province in 2022 showied an increase in cases from 274 to 327 patients. Washingv the face using tihe correct technique is the most imiportant factor in supporitiing the success of acne vulgaris treatment. This research was conductevdi with the aim of determining the relationship between face washing technvique and the sucicess of acne vulgaris treatment. The results of the univariate analysis showed that the majority of responidents iperformed face washingi technique propierly (67.1%), and thie majority showevdv success in acne vulgaris treatment i71.4%). The results of the bivariate analysis revealed a relationship between face wasvvhing technique and the success of acnei vulgaris treatment (p-value = 0.001, OR = 7.429). Therefore, iit is reciommended fior healthcare professionais to assist patienvts in understanding the importance of washing the face with the correct techniqiue as part of acnve vulgaris trveatment. Keywords: Face Washing Technique, Treatment Success, Acne Vulgaris ABSTRAK Salah satu perimasalahan kulit yang paling serinig ditemukan adialah acne vulgaris. Prevalensi acne vulgaris di Duinia tahun 2022 sekitar 80%, di Indonesia sekitar 85%, sedangkanv di Provinsi Lampung sekitar 69,7%. iData di Poli Deirmatologi RSUD dr. vH. Abdvul iMoeloek Provinsi Lampung tahun 2022 manunjiukan peningkatan kasus dari 274 menjadi 327 pasiien. Mencuci iwajah meinggunakan tekniik yang bienar merupakan vhal yang paling pevnting untuk dapat mieinunjang keberhasilan pengobatan acne vulgaris. Penelitian dilakukan dengan tujuan dikietahuinyai hubungain teknik miencuci wajah diengan keberhasilain pengobatan acne vulgaris. Hasil analisis univariat diperolehi bavhwa sebagian besar responiden melakukain teknik mevncuci wajah dengain baiki (67,1%i), dan sebagian ibesar menunjukan adanya keberhasilan dalam pengobatan acne vulgaris (71,4%). Hasil analisis biivariat diperoleh advanya hubunvgan teknik mencuci wajah dengain keberhasilan pengobiatan acne vulgaris (ip-value = 0,001, OR= 7,429). Oleh karenia itu, disarankan bagi tenagia kesehatan davpat membantu pasien dalam memahami pentinignya mencuci wajah dengavn teknik yang tepat sebagiai bagian dvari periawatan acnei vulgaris. Kata Kunci: Teknik Mencucii Wajah, Keberhasilan Pengobvatan, Acne Vulgaris
Perbedaan Tekanan Darah dan Frekuensi Nadi Sebelum dan Sesudah Minum Teh pada Mahasiswa/i Fakultas Kedokteran Universitas Tarumanagara Tahun Angkatan 2021
Authors: Evangelia Laura , Lontoh Susy Olivia 
Published: November 2024

ABSTRACT Tea is one of the caffeinated drinks most frequently consumed among medical students. Caffeine consumption is one of the external factors that plays a role in increasing blood pressure. Caffeine consumed as much as 300 mg can increase systolic blood pressure by 5-15 mmHg and diastolic 5-10 mmHg within 15 minutes and this increase in blood pressure lasts up to 2 hours. Research on the effects of tea on blood pressure and pulse rate among medical students is limited. To determine the difference in mean blood pressure and pulse frequency before and after drinking tea in students of the Faculty of Medicine, Tarumanagara University. This research used an observational experimental research design with pre-test and post-test. The research subjects were students from the Faculty of Medicine, Tarumanagara University class of 2021 who met the inclusion criteria with a sample size of 55 students. Data collection was carried out using a simple non random consecutive sampling technique. The results showed that there was a difference in mean blood pressure and pulse frequency after drinking tea compared to before drinking tea (p < 0.05). Tea consumption can cause an increase in blood pressure and pulse rate after 5, 10, and 15 minutes of drinking tea. This can happen because tea contains caffeine which causes an increase in blood pressure in the short term. Keywords: Tea, Caffeine, Blood Pressure, Pulse ABSTRAK Teh merupakan salah satu minuman berkafein yang paling sering dikonsumsi di kalangan mahasiswa kedokteran. Konsumsi kafein menjadi salah satu faktor eksternal yang berperan meningkatkan tekanan darah. Kafein yang dikonsumsi sebanyak 300 mg dapat meningkatkan tekanan darah sistolik 5-15 mmHg dan diastolik 5-10 mmHg dalam waktu 15 menit dan peningkatan tekanan darah ini bertahan hingga 2 jam. Penelitian mengenai efek teh terhadap tekanan darah dan denyut nadi di kalangan mahasiswa kedokteran masih terbatas. Untuk mengetahui perbedaan rerata tekanan darah dan frekuensi nadi sebelum dan sesudah minum teh pada mahasiswa/i Fakultas Kedokteran Universitas Tarumanagara. Penelitian ini menggunakan desain penelitian eksperimen observasional dengan pre test dan post test. Pengumpulan data dilakukan dengan teknik non random consecutive sampling. Hasil penelitian menunjukkan bahwa terdapat perbedaan rerata tekanan darah dan frekuensi nadi sesudah minum teh dibandingkan sebelum minum teh (p < 0,05). Konsumsi teh dapat menyebabkan peningkatan tekanan darah serta frekuensi nadi setelah 5, 10, dan 15 menit mengonsumsi teh. Hal ini dapat terjadi karena teh mengandung kafein yang menyebabkan peningkatan tekanan darah dalam jangka pendek. Kata Kunci: Teh, Kafein, Tekanan Darah, Denyut Nadi
Bibliometric Analysis of Influencing Factors on Nurse Performance
Authors: Adelina I Dewa Ayu Yulia , Noor Zairin , Noor Meitria Syahadatina , Wydiamala Erida , Marlinae Lenie 
Published: November 2024

ABSTRACT Nurse performance is a key factor in determining the success of patient recovery and patient satisfaction with the services provided. This article provides a bibiometric analysis of nurse performance by analysing publication trends, geographical contributions, journal types and research topic networks. Data were collected using the Publish or Perish (PoP) application and visualised using VOSViewer. The results showed that the publication trend related to nurse performance has increased with research topics including nursing, workload, hospital, stress and performance quality. The United States, Iran, China, Australia and Brazil were identified as the main contributors to these publications. This analysis provides a visual overview of research topics related to nurse performance, as well as identifying potential areas for further research. Keywords: Nurse, Workload, Hospital, Stress, Quality, Work Environment, Nurse Performance
Utilization of biodegradable carrier-based nano herbicide formulations for sustainable weed management in agriculture
Authors: Jayasoorya Rajasekaran , Kumar Pradeesh 
Published: November 2024

Recently, the injudicious use of herbicides in agriculture is causing numerous hazards that affect the environment and living organisms. To achieve the SDG 2030 agenda goal 12- “Ensure sustainable consumption and production patterns,” there is an urgent need to shift towards using toxic-free agricultural inputs. Various techniques are widely adopted to control weed growth and development, but farmers mostly rely on herbicide application. Nanotechnology-enabled herbicide formulations are more sustainable and efficient in weed control than traditional sources. The nanoherbicides enable lesser application frequency and minimum quantity requirement, thereby preventing herbicide accumulation in soil and water bodies. Mainly nano-mediated biodegradable carrier-based herbicides possess properties of prolonged release, targeted inhibition, reduced mobility in soil, better adhesion to the plant surface, and retards rapid degradation of active ingredients (AIs), which increase herbicide use efficiency against weeds. Biodegradable carrier materials are cost-effective and readily available from living/non-living organisms and mineral sources, which can be an alternate source for metal/metal-oxide carrier materials. Materials like chitosan, plant derivatives, clay particles, and synthetic polymers are notable carrier materials reported for encapsulating or loading herbicide molecules. Applying nano-mediated herbicides is an innovative methodology for controlling weeds while considering environmental safety. This review focused mainly on recent advances in biodegradable carrier-based herbicide application in agriculture to mitigate the crisis in sustainable weed management. The ultimate objective of this manuscript is to serve as a source of reference material for exploring the nano-based herbicide formulations, their mobility, fate, and future perspectives.
Reducing ammonia volatilization in rice paddy: the importance of lower fertilizer rates and soil incorporation
Authors: Canatoy Ronley C. , Cho Song Rae , Galgo Snowie Jane C. , Kim Pil Joo , Kim Gil Won 
Published: November 2024

In rice paddies, which exhibit higher ammonia (NH₃) emission factors than upland soils, identifying key drivers of NH₃ flux intensity is crucial. Contrary to the commonly held view that NH₃ flux is primarily governed by soil ammonium (NH₄⁺) concentrations, we found no significant relationship between NH₃ flux and NH₄⁺ levels in the soil during rice cultivation. To pinpoint a primary factor influencing NH₃ flux intensity under conventional rice cropping practices, we conducted a 2-year field study applying four nitrogen (N) fertilization rates (0, 45, 90, and 180 kg N ha⁻¹) using urea [(NH₂)₂CO], the most common N fertilizer. NH₃ emissions were tracked using the ventilation method. Following N application, NH₃ flux sharply increased but rapidly returned to baseline. Half of the N applied as a basal fertilizer was incorporated within the soil, contributing only 10% of total NH₃ emissions. In contrast, top-dressed applications—20% of total N at the tillering stage and 30% at panicle initiation—accounted for approximately 90% of NH₃ loss. Seasonal NH₃ flux increased quadratically with rising N application rates, correlating strongly with NH₄⁺ concentrations in floodwater rather than soil. Grain yield responded quadratically to N levels, peaking at 120 kg N ha⁻¹ with a 37% increase over control yields. NH₃ flux intensity, defined as seasonal NH₃ flux per unit of grain yield, showed a quadratic response to N fertilization, decreasing with initial fertilizer additions (up to 38 kg N ha⁻¹) but then sharply increased with further N fertilization increase. Hence, reducing NH₄⁺ concentrations in floodwater through moderated N application and deeper fertilizer placement could be essential for minimizing NH₃ volatilization in rice systems.
Exploring the therapeutic potency of cryptotanshinone in cervical cancer: a multi-omics and network pharmacology approach
Authors: Lu Zenghong , Zhu Gangfeng , Feng Xiaofei , Xiang Yi , Chen Cixiang , Yuan Huiting , Chen Zhixing 
Published: November 2024

IntroductionCervical cancer remains a significant challenge in oncology with an escalating demand for novel therapeutic strategies that can navigate the complexities of its pathophysiology. This study elucidated the antineoplastic effects of cryptotanshinone, a derivative of danshen (Salvia miltiorrhiza), a herb widely utilized in traditional Chinese medicine practices.MethodsEmploying a comprehensive multi-omics approach, including transcriptomic, proteomic, and bioinformatics analyses, we investigated the potential effects of cryptotanshinone on cervical cancer through data mining and computational analysis.Results and DiscussionOur results demonstrated that the potential of cryptotanshinone to disrupted cancer cell proliferation and induced apoptosis may be ascribed to its modulation of gene expression and interaction with specific protein networks. Furthermore, network pharmacology and pathway enrichment analyses identified critical hubs and signaling pathways, suggesting a multi-targeted mechanism of action. Furthermore, the establishment of a prognostic model, which is founded upon differentially expressed genes linked to cryptotanshinone treatment, underscores its promising role as both a prognostic biomarker and a therapeutic agent. These insights pave the way for the integration of cryptotanshinone into therapeutic regimens, offering a promising avenue for enhancing the efficacy of cervical cancer treatment and patient outcomes.
T-cell receptor and B-cell receptor repertoires profiling in pleural tuberculosis
Authors: Du Fengjiao , Deng Yunyun , Deng Ling , Du Boping , Xing Aiying , Tao Hong , Li Hua , Xie Li , Zhang Xinyong , Sun Tao , Li Hao 
Published: November 2024

BackgroundTuberculosis (TB) is a leading cause of death worldwide from a single infectious agent. In China the most common extra-pulmonary TB (EPTB) is pleural tuberculosis (PLTB). An important clinical feature of PLTB is that the lymphocytes associated with TB will accumulate in the pleural fluid. The adaptive immune repertoires play important roles in Mycobacterium tuberculosis (Mtb) infection.MethodsIn this study, 10 PLTB patients were enrolled, and their Peripheral Blood Mononuclear Cells(PBMCs) and Pleural Effusion Mononuclear Cells(PEMCs) were collected. After T cells were purified from PBMCs and PEMCs, high-throughput immunosequencing of the TCRβ chain (TRB), TCRγ chain(TRG), and B cell receptor(BCR) immunoglobulin heavy chain (IGH) were conducted on these samples.ResultsThe TRB, TRG, and BCR IGH repertoires were characterized between the pleural effusion and blood in PLTB patients, and the shared clones were analyzed and collected. The binding activity of antibodies in plasma and pleural effusion to Mtb antigens was tested which indicates that different antibodies responses to Mtb antigens in plasma and pleural effusion in PLTB patients. Moreover, GLIPH2 was used to identify the specificity groups of TRB clusters and Mtb-specific TRB sequences were analyzed and collected by VJ mapping.ConclusionWe characterize the adaptive immune repertoires and identify the shared clones and Mtb-specific clones in pleural effusion and blood in PLTB patients which can give important clues for TB diagnosis, treatment, and vaccine development.
Emerging roles of mechanosensitive ion channels in ventilator induced lung injury: a systematic review
Authors: Liu Gang , Dong Bin-bin , Devanarayana Shalika , Chen Rong-Chang , Liu Qi 
Published: November 2024

BackgroundThe pathogenetic mechanisms of ventilator-induced lung injury (VILI) still need to be elucidated. The mechanical forces during mechanical ventilation are continually sensed and transmitted by mechanosensitive ion channels (MSICs) in pulmonary endothelial, epithelial, and immune cells. In recent years, MSICs have been shown to be involved in VILI.MethodsA systematic search across PubMed, the Cochrane Library, Web of Science, and ScienceDirect was performed from inception to March 2024, and the review was conducted in accordance with PRISMA guidelines. The potential eligible studies were evaluated by two authors independently. Study characteristics, quality assessment, and potential mechanisms were analyzed.ResultsWe included 23 eligible studies, most of which were performed with murine animals in vivo. At the in vitro level, 52% and 48% of the experiments were conducted with human or animal cells, respectively. No clinical studies were found. The most reported MSICs include Piezo channels, transient receptor potential channels, potassium channels, and stretch-activated sodium channels. Piezo1 has been the most concerned channel in the recent five years. This study found that signal pathways, such as RhoA/ROCK1, could be enhanced by cyclic stretch-activated MSICs, which contribute to VILI through dysregulated inflammation and immune responses mediated by ion transport. The review indicates the emerging role of MSICs in the pathogenesis of VILI, especially as a signal-transmitting link between mechanical stretch and pathogenesis such as inflammation, disruption of cell junctions, and edema formation.ConclusionsMechanical stretch stimulates MSICs to increase transcellular ion exchange and subsequently generates VILI through inflammation and other pathogeneses mediated by MSICs signal-transmitting pathways. These findings make it possible to identify potential therapeutic targets for the prevention of lung injury through further exploration and more studies.Systematic review registrationhttps://inplasy.com/inplasy-2024-10-0115/, identifier INPLASY2024100115.