bluuebunny/crossref_metadata_2025_split huggingface dataset:
Covalent Organic Framework Encapsulating Layered Oxide Perovskite for Efficient Photosynthesis of H2O2
Authors: Teng Yuan , Zhao Jing , Ye Zi‐Ming , Tan Chao‐Wen , Ning Ling‐Ling , Zhou Yi‐Yang , Wu Zhilian , Kuang Dai‐Bin , Li Youji 
Published: December 2024

AbstractDriving efficient artificial photosynthesis of H2O2 is highly desirable in both academic and industrial fields. Here, a new core–shell Bi3TiNbO9@C4N heterojunction is constructed for efficient photocatalytic H2O2 production by in situ encapsulating an ultrathin layer of covalent organic framework material (C4N) on Aurivillius‐type Bi3TiNbO9 microsheets. The porous C4N layer is found to enhance visible‐light absorption ability and facilitate the adsorption and activation of the reactants and intermediates. The hybrid heterojunction follows an S‐scheme charge transfer with the assistance of a strong internal electric field (IEF), which promotes the spatial separation of photogenerated carriers effectively and maintains their strong redox abilities. As a result, the optimized Bi3TiNbO9@C4N unveils a high H2O2 yield rate of 1.25(2) mmol g−1 h−1 in the absence of sacrificial agents and cocatalyst, 10.9 and 3.5 folds higher than those of pristine Bi3TiNbO9 and C4N catalysts, respectively. This work provides an in situ encapsulating strategy to decorate covalent organic frameworks (COFs) on oxide perovskites for artificial photosynthesis of H2O2, which may stimulate the intensive investigation interests of functional materials/COFs heterojunction materials for various photocatalysis applications.
Voltage Noise Failure Induced by Li Dendritic Micro‐Penetration in All‐Solid‐State Li‐Metal Battery with Composite Solid Electrolyte
Authors: Yun Heejun , Lee Eunji , Han Juyeon , Jang Eunbin , Cho Jinil , Kim Heebae , Lee Jeewon , Min Byeongyun , Lee Jemin , Piao Yuanzhe , Yoo Jeeyoung , Kim Youn Sang 
Published: December 2024

AbstractAll‐solid‐state Li‐metal batteries (ASSLBs) are the most attractive next‐generation batteries due to intrinsic safety and high energy density. Particularly, composite solid electrolyte (CSE)‐based ASSLBs, highly compatible with conventional Li‐ion batteries, are nearing commercialization. However, the understanding of ASSLBs’ failure remains deficient, thereby considerably hindering their advancement. Herein, the unrecognized failing mode of ASSLBs, voltage noise failure (VNF), characterized by irregular charging voltage configuration, is identified using comprehensive techniques, including laser‐induced breakdown spectroscopy. The VNF originates from micro‐penetration of Li dendrites, which is demonstrated through direct observation of 3D Li concentration map in CSE. In this phenomenon, the transition metals, dissolved from the cathode, hop to the anode and serve as seeds for dendritic growth in VNF. Inspired by this mechanism and with the aid of DFT calculations, a transition metal scavenging layer is proposed using Prussian blue analogue at the cathode‐CSE interface. Consequently, ASSLBs with transition metal scavenging layer exhibit superior capacity (189 mAh g−1 at 0.5 C, NCM811) and stable cyclability (1200 cycles without failure).
Evolution of Supramolecular Coordination Assemblies Visually Monitored by Time‐Dependent Multicolor Fluorescence
Authors: Xu Hanren , Wang Qian , Qi Zhen , Li Xianghao , Lei Yifan , An Hongyu , Tian He , Qu Da‐Hui 
Published: December 2024

AbstractSupramolecular coordination assemblies play an important role in both material science and biological systems. Despite significant efforts in their development, most existing examples are thermodynamically controlled, which lack the adaptability and autonomy essential for the creation of advanced materials. In this work, we have developed non‐equilibrium coordination assembly systems that can evolve over time through a combination of thermodynamic and kinetic controls. The introduction of zinc ions resulted in the formation of metastable fiber assemblies in a kinetically trapped state, which autonomously converted to thermodynamically stable nanosheets over time. This evolution process can be regulated by external stimuli and visually monitored by the time‐dependent multicolor fluorescence. The construction strategy was versatile across other various ions such as Ca2+, Mg2+, and Al3+, offering inspiring insights for the design of complex systems that operated both in and out of their thermodynamic equilibrium.
Investigating Interaction Dynamics of an Enantioselective Peptide‐Catalyzed Acylation Reaction
Authors: Brauser Matthias , Petzold Katja , Thiele Christina M. 
Published: December 2024

AbstractModern nuclear magnetic resonance (NMR) methods like carbon relaxation dispersion in the rotating frame (13C−R1ρ) and proton chemical exchange saturation transfer (1H‐CEST) are key methods to investigate molecular recognition in biomacromolecules and to detect molecular motions on the μs to s timescale, revealing transient conformational states. Changes in kinetics can be linked to binding, folding, or catalytic events. Here, we investigated whether these methods allow detection of changes in the dynamics of a small, highly selective peptide catalyst during recognition of its enantiomeric substrates. The flexible tetrapeptide Boc‐l‐(π‐Me)−His−AGly‐l−Cha−l‐Phe−OMe, used for the monoacetylation of cycloalkane‐diols, is probed at natural abundance using 13C‐R1ρ and 1H‐CEST. Indeed, we detected differences in dynamics of the peptide upon interaction with the diol. Importantly, these differ depending on the enantiomer of the substrate used. These enantiospecific influences of the substrates on the dynamics of the peptide are rationalized using computational techniques. We find that even though one enantiomer reacts faster, as confirmed by reaction monitoring, the other is more tightly bound in DCM (as confirmed by 1H‐saturation transfer difference (STD) measurements). These findings provide insights into the recognition of the substrates and explain the selectivity differences observed between the solvents toluene and DCM.
Concise Three Step Synthesis of the Bioactive Alkaloid Huajiaosimuline via a Zn(OTf)2‐Promoted Meinwald Rearrangement
Authors: Adessi Tonino G. , Centurión Enzo F. G. , Horra Camila De La , Chocan Camila , Bajicoff Sofía , Blank Viviana , Roguin Leonor , Riveira Martín J. 
Published: December 2024

ABSTRACTThe synthesis of the biologically active alkaloid huajiaosimulne, isolated from the roots of Zanthoxylum simulans, is reported. The natural product was assembled from simple commercial reagents via initial domino Knoevenagel/oxa‐6π‐electrocyclization followed by epoxidation and an epoxide/ketone rearrangement promoted by Zn(OTf)2. In vitro cytotoxicity assays identified natural products huajiaosimuline and simulansine as moderate antiproliferative agents against murine colon cancer CT26 cells.
Flavin‐Dependent Nitroreductases: Privileged Enzymes for Chemical and Photochemical Synthesis
Authors: Russo Sara , Luján Alejandro Prats , Fraaije Marco W. , Poelarends Gerrit J. 
Published: December 2024

AbstractNitroreductases, present within both prokaryotes and eukaryotes, form a group of flavin‐dependent enzymes capable of reducing nitro compounds using NAD(P)H as reducing agent. These enzymes have been widely studied due to their diverse roles in bioremediation, cancer therapy, cell ablation, and antimicrobial resistance. In recent times, the versatility of nitroreductases has been expanded toward the synthesis of highly valuable compounds such as aromatic and aliphatic amines, azoxy and azobenzenes, as well as N‐heterocycles. This review examines the biological role and diversity of flavin‐dependent nitroreductases, and highlights their current and potential future application as biocatalysts for the sustainable synthesis of nitrogen‐containing pharmaceutical compounds and bulk chemicals.
Amorphous Al2O3‐Supported NiMo Nanocatalysts: Boosting Type 2 Sites for Hydrodesulfurization Reaction
Authors: Arora Shalini , Khan Rashmi , Sivakumar Sri 
Published: December 2024

AbstractHerein, we report superior hydrodesulfurization (HDS) catalytic activity of ultrasmall NiMo supported on amorphous‐Al2O3 (A‐Al2O3) catalysts with enhanced type 2 sites. A‐Al2O3 was chosen as support because it has lower surface energy, better physicochemical properties, and enhanced acidic sites than the crystalline alumina phase. At 20% metal oxide composition, NiMo supported on A‐Al2O3 catalyst showed weak metal–support interaction, a higher sulfidation degree (80%), and a higher amount of NiMoS sites (14.9 × 1019 sites/mg) with optimum stacking degree (2.5), leading to 1.4 and 1.2 times higher reaction rate constant and turnover frequency (TOF), respectively, than wet‐impregnated NiMo supported on γ‐Al2O3 catalysts. Further, the Density Functional Theory (DFT) study supports the formation of a higher degree of type 2 sites (by confirming weaker active metal interaction for A‐Al2O3 surface than crystalline γ‐Al2O3), which leads to increased HDS catalytic activity.
Influence of External Factors on Recovery and Persistence Parameters of Chemical Weapons–Related Alcohols and Thiols in Concrete Samples
Authors: Rozsypal Tomáš , Pavlík Jakub , Kareš Ondřej , Štoller Jiří 
Published: December 2024

ABSTRACTThe contamination of materials in urban areas by chemical weapons is a critical issue, especially as these materials can serve as key evidence in forensic investigations. Concrete, commonly found in urban environments, is highly porous and can retain chemical residues. However, its alkaline nature accelerates the degradation of chemical warfare agents, complicating the recovery of usable evidence. This study explores the recovery and persistence of alcohols and thiols, final degradation products of nerve and blistering agents, from two types of concrete matrices: lightweight concrete formworks and dense, steel‐reinforced concrete blocks. Using an optimized method, uncrushed concrete fragments (up to 85 g) were extracted with acetone, monitoring two critical parameters: apparent recovery and persistence. The influence of external conditions, such as water addition, temperatures between 5°C and 35°C, and varying airflow speeds (1.7–5.1 m·s−1), was systematically evaluated. Reference conditions involved dried concrete at 22°C with no airflow. The findings revealed that alcohol recovery aligned with the volatility of the compounds, with denser concrete exhibiting lower recoveries but greater persistence. Thiols quickly converted to disulfides. Notably, temperature and moisture had the most profound effects on the recovery and persistence of the chemicals. These results highlight the importance of considering environmental factors when assessing chemical warfare agents and their degradation products in concrete, offering insights relevant to forensic science, environmental safety, and military defense. The study demonstrates how concrete's properties and external conditions can alter the forensic traceability of chemical contaminants.
Beyond Collective Victimhood: How Diverse Conflict Knowledge Relates to Community Cohesion
Authors: Penić Sandra , Elcheroth Guy , Bilali Rezarta 
Published: December 2024

ABSTRACTIn conflict‐affected societies, collective victimization can undermine social cohesion or foster narrow ingroup bonding and parochialism. We examine whether the possibility to know and freely communicate about diverse conflict experiences, which go beyond collective (ingroup) victimhood, can serve as a resource for community cohesion (i.e., community attachment and efficacy). Nationally representative surveys from two conflict‐ridden societies, Sri Lanka (N = 1188) and the Occupied Palestinian Territory (N = 1000), reveal that individuals with broader knowledge of diverse conflict experiences exhibit stronger attachment to their local communities and perceive them as more efficacious, but only when they believe knowledge of these experiences can be shared within their community. Conversely, diverse conflict knowledge is related to a lower sense of community cohesion when individuals perceive diverse conflict experiences as unspeakable in their community. The findings contribute to our understanding of the potential effects of violent conflict on social cohesion and highlight the importance of openness to discuss the full range of conflict experiences.
How Do People Morally Judge Corruption? A Comparison Between the Netherlands and Indonesia
Authors: Aurelia Meta Zahro , van Prooijen Jan‐Willem , Van Lange Paul A. M. 
Published: December 2024

ABSTRACTExtant research on corruption has uncovered the important role of norms. Yet, little is known about how people view specific acts of corruption in countries that differ in the prevalence of corruption. The present research examines moral judgements of four different types of corrupt acts in a high‐ versus low‐corruption country, thereby providing a critical test of two opposing hypotheses. The descriptive norms approach predicts that citizens of a high‐corruption country will be morally more lenient than citizens of a low‐corruption country. The relative deprivation approach predicts the opposite, that citizens of a high‐corruption country will morally condemn corrupt acts stronger than citizens of a low‐corruption country. Drawing samples from the Netherlands and Indonesia (a low‐ vs. high‐corruption country), two experiments (total N = 477) show that Dutch participants are often more morally permissive towards corruption than Indonesians, although specific results varied for the four types of corruption. This largely supported the relative deprivation approach. In addition, Indonesian participants expressed more disappointment and anger towards corruption than Dutch participants. This research suggests that feeling deprived through regular corruption experiences leads people to condemn corrupt acts more strongly.
Clinical characteristics of 30 children with severe acute SARS‐CoV‐2 infection
Authors: Li Weijun , Zhu Danping , Xiao Weiqiang , Liang Defeng , Deng Huarong , Zheng Jipeng , Wang Qiang , Liu Guangming , Li Peiqing 
Published: December 2024

AbstractBackgroundTo describe the characteristics of pediatric patients with severe COVID‐19 in China and identify the clinical variables associated with cardiovascular involvement, severe neurological complications, and disease prognosis.MethodsA retrospective surveillance study were conducted from December 1 to 31, 2022, in Guangzhou Women and Children's Medical Center. Clinical and laboratory characteristics were abstracted by medical record review and were further analyzed according to different manifestations.ResultsA total of 30 children (median age, 27.5 months; 36.7% female) met the criteria for the diagnosis of severe COVID‐19. The top five presented symptoms were fever, convulsions, cough, polypnea, and fatigue. Compared with shock absent patients, the cardiovascular involved patients had different laboratory features, including elevated aspartate aminotransferase (AST), lactic acid levels, and abnormalities in coagulation parameters. Higher levels of alanine aminotransferase, AST, lactic dehydrogenase, creatinine, lactic acid, and abnormal coagulant function were more common in patients with severe neurological complications and patients who died during hospitalization. Higher lymphocyte counts and serum sodium concentrations were also observed in non‐survivors.ConclusionSevere COVID‐19 pediatric patients had varied clinical characteristics. Laboratory features associated with cardiovascular involvement, severe neurological complications, and adverse outcomes may facilitate early identification of the severe patients.
Recurrent spontaneous ovarian hyperstimulation in a young nonpregnant Chinese woman with Rathke cleft cyst and a KISS1R variant: A rare case report and literature review
Authors: Lin Yueming , Qiao Huimin , Ding Miao , Zhou Shengning , Wu Yingchen 
Published: December 2024

AbstractUnexplained spontaneous ovarian hyperstimulation syndrome (sOHSS) in a nonpregnant young woman is rare, with fewer than five cases documented in the literature. Although four distinct causative types of sOHSS have been identified, some cases remain beyond the scope of our current understanding. A young Chinese woman with sOHSS presented on multiple occasions with sOHSS between the ages of 18.6 and 20.6 years, with acute abdominal discomfort, ascites, hemoconcentration, and pronounced ovarian enlargement coinciding with minor ovulatory anomalies. During the most recent episode, concern regarding a malignant ovarian neoplasm led to emergent unilateral salpingo‐oophorectomy. Remarkably, her menstrual cycle normalized after surgery, with no subsequent recurrence of sOHSS. Subsequent diagnostic evaluations identified a Rathke cleft cyst (RCC) in the pituitary gland and a heterozygous mutation in the KISS1R gene. Neither of these findings corresponded with any of the four informally recognized causes of sOHSS, suggesting a hitherto unrecognized pathology. RCCs may cause OHSS by disrupting the endocrine system, while interactions between the kisspeptin system and estradiol may reach a critical threshold, culminating in sOHSS. This case provides important insights into sOHSS and will hopefully spearhead further research into pituitary anomalies and the intricacies of the kisspeptin system. Clinicians are urged to maintain a high level of vigilance for similar presentations and ensure timely and tailored therapeutic interventions.
Best practices for associational advocacy in the counseling profession: A grounded theory investigation
Authors: Pester Boyd Danielle , Nice Matthew L. , Hays Danica G. , Lenz A. Stephen 
Published: December 2024

AbstractThrough this grounded theory study, the authors present the model for advancing professions (MAP) through advocacy, which identifies how counseling‐related professional organizations develop, implement, assess, and sustain public policy and advocacy initiatives, grounded in 11 participants’ experiences across six professional associations. Although previous models supported the work of individual advocacy within the field of counseling, the MAP through advocacy provides a clear and robust associational infrastructure and a set of best practices to guide counseling organizations in public policy and advocacy initiatives that advance the profession. Implications for the counseling profession and how the model can inform and enhance the mission of the ACA, and its divisions, regions, and state organizations are discussed.
Opening wedge high tibial osteotomy yields comparable to superior outcomes to unicompartmental knee arthroplasty at 2 years of follow‐up in patients suffering from Ahlbäck III knee osteoarthritis: A propensity score‐matched analysis
Authors: Onishi Shintaro , Jacquet Christophe , Nakayama Hiroshi , Argenson Jean Noël , Ollivier Matthieu 
Published: December 2024

AbstractPurposeTo compare the clinical outcomes between opening wedge high tibial osteotomy (OWHTO) and unicompartmental knee arthroplasty (UKA) in patients with Ahlbäck Grade 3 medial compartmental knee osteoarthritis (OA) using a propensity score matching (PSM) analysis.MethodsThis retrospective study included all OWHTO and UKA procedures performed between 2016 and 2021 at a single institution. Inclusion criteria were patients diagnosed with medial knee OA, specifically Ahlbäck Grade 3 arthritis. Clinical outcomes were assessed using the Knee Injury and Osteoarthritis Outcome Score (KOOS). Radiographic parameters included hip–knee–ankle (HKA), medial proximal tibial angle (MPTA), lateral distal femoral angle (LDFA) and joint line convergence angle (JLCA). Primary outcomes included improvement in clinical scores at 3, 12 and 24 months post‐operatively. Secondary outcomes included radiographic parameters, complication rates and re‐intervention rates. One‐to‐one PSM was conducted based on gender, age and preoperative KOOS pain scores.ResultsAfter evaluating eligibility using PSM, a total of 50 knees in the UKA group and 50 knees in the OWHTO group were included. There was no significant difference between groups in preoperative overall KOOS, but the UKA group had better overall KOOS at 3 months (p < 0.001). However, the overall KOOS at 12 and 24 months were superior in the OWHTO group compared to the UKA group (12 months; 84.6 ± 4.9 vs. 86.4 ± 2.9, p = 0.022, 24 months; 84.9 ± 5.3 vs. 87.0 ± 3.7, p = 0.022). As for post‐operative radiological parameters, HKA, MPTA, LDFA and JLCA were higher in the OWHTO group at 24 months post‐operatively. No significant differences were noted in the rates of complication or re‐intervention between groups.ConclusionsOWHTO can provide outcomes equal to or better than UKA at 24 months post‐operatively in patients with advanced knee OA.Level of EvidenceLevel Ⅲ, Prospective designed retrospective comparative study.
Vocal cord dysfunction: Does laryngeal adduction on laryngoscopy predict disease severity and response to laryngeal retraining therapy?
Authors: Ahmadian David , Wehbi Nader , Gleadhill Claire M. , Monahan Natalie , Gallego Charles J. , Skirko Jonathan R. , Yip Helena T. 
Published: December 2024

AbstractIntroductionVocal cord dysfunction (VCD) is a complex disorder characterized by episodic adduction of the vocal folds during inspiration and expiration, which can lead to dyspnea, wheezing, cough, and acute‐onset respiratory distress. Currently, there is a lack of standardized criteria among treating physicians across multiple disciplines, including otolaryngologists, pulmonologists, allergists, and speech and language pathologists, for diagnosis and treatment of VCD, although laryngeal‐respiratory retraining therapy (LRT) has emerged as the preferred treatment modality.ObjectiveIn the present study, we examined the efficacy of LRT in patients presenting with a clinical diagnosis of VCD in the presence and absence of laryngeal adduction on laryngoscopy.ResultsOverall, 74.1% of the cohort showed a response to LRT, of which 62.1% were partial and 12.1% were significant responses. When comparing between patients with and without laryngeal adduction on laryngoscopy, there were no significant differences in the number of sessions of LRT undertaken, mean time to response, and overall response rate between the groups.ConclusionOur findings suggest that LRT should be utilized for all patients presenting with symptoms of VCD, even in the absence of laryngeal adduction on laryngoscopy.