bluuebunny/crossref_metadata_2025_split huggingface dataset:
Building brand and fan relationships through social media
Authors: Thompson Ashleigh-Jane , Martin Andrew J. , Gee Sarah , Geurin Andrea N. 
Published: May 2018

Purpose
As the popularity of social media increases, sports brands must develop specific strategies to use them to enhance fan loyalty and build brand equity. The purpose of this paper is to explore how two social media platforms were utilised by the Grand Slam tennis events to achieve branding and relationship marketing goals.

Design/methodology/approach
A content analytic design was employed to examine Twitter and Facebook posts from the official accounts during, and post-, each respective event.

Findings
Both sites were utilised to cultivate long-term relationships with fans and develop brand loyalty, rather than to undertake short-term marketing activations. However, these sites appear to serve a different purpose, and therefore unique strategies are required to leverage opportunities afforded by each. Interestingly, brand associations were utilised more frequently during the post-event time period.

Practical implications
This study offers practitioners with useful insight on branding and relationship-building strategies across two social platforms. These results suggest that strategies appear dependent on the event, timeframe and specific platform. Moreover, the events’ differences in post use and focus may also indicate some differences related to event branding in an international context. Furthermore, sport organisations should look to leverage creative strategies to overcome limitations that platform-specific functionality may impose.

Originality/value
This study offers unique insights brand-building efforts in an international event setting, which differ in a range of contextual factors that impact on social media utilisation.
Suffering in receivers: Negative effects of noise persist regardless of experience in female anurans
Authors: Senzaki Masayuki , Kadoya Taku , Francis Clinton D. , Ishiyama Nobuo , Nakamura Futoshi 
Published: May 2018

Abstract

Anthropogenic noise is widespread, and growing evidence suggests that it can negatively affect animals through many different mechanisms including masking of cues and signals, distraction, and aversion to noise.

Acoustic masking has received the most attention from researchers and recent evidence suggests that masking effects can be mitigated by alteration of signal frequencies or amplitudes by signalers. Additionally, alteration can be a learned response via prior experience with noise exposure. However, it remains unclear whether distraction or aversive effects due to noise can be mitigated by prior experience with noise, especially among signal receivers.

Here, we addressed this gap by separating mechanisms of noise disturbances on female phonotaxis towards male advertisement calls in anurans. To do this, we experimentally examined phonotaxis of gravid females that differ in their prior experience with noise under three acoustic manipulations: spectrally overlapping and non‐overlapping noise that either mask or do not mask male advertisement calls respectively, plus a silent control.

We confirm two experience‐dependent responses of noisy‐site individuals relative to quiet‐site individuals: faster initiation of phonotaxis under non‐overlapping noise and a stronger aversive response against overlapping noise. However, we showed that, for both noisy‐ versus quiet‐site individuals, both overlapping and non‐overlapping noise treatments resulted in delayed initiation and disorientation of phonotaxis relative to silent control treatments.

Our study provides the first evidence to demonstrate that, although prior experience appears to mitigate the negative effects of distraction or aversion to noise, prior experience falls short of fully compensating for disrupted orientation through phonotaxis. Additionally, although most studies have emphasized masking of biologically relevant cues and signals as the most prominent mechanism by which noise negatively affects wild organisms, we show that non‐overlapping noise, which cannot cause signal and cue masking, can have negative consequences via distraction or aversive responses. This finding suggests that noise impacts could extend well beyond contexts involving acoustic cue detection and discrimination and deserves increased attention by researchers.

A plain language summary is available for this article.
Grey wolf optimizer: a new strategy to invert geophysical data sets
Authors: Agarwal Aayush , Chandra Akash , Shalivahan Shalivahan , Singh Roshan K 
Published: May 2018

ABSTRACTThere is no meta‐heuristic approach best suited for solving all optimization problems making this field of study highly active. This results in enhancing current approaches and proposing new meta‐heuristic algorithms. Out of all meta‐heuristic algorithms, swarm intelligence is preferred as it can preserve information about the search space over the course of iterations and usually has fewer tuning parameters. Grey Wolves, considered as apex predators, motivated us to simulate Grey Wolves in the optimization of geophysical data sets. The grey wolf optimizer is a swarm‐based meta‐heuristic algorithm, inspired by mimicking the social leadership hierarchy and hunting behaviour of Grey Wolves. The leadership hierarchy is simulated by alpha, beta, delta and omega types of wolves. The three main phases of hunting, that is searching, encircling and attacking prey, is implemented to perform the optimization. To evaluate the efficacy of the grey wolf optimizer, we performed inversion on the total gradient of magnetic, gravity and self‐potential anomalies. The results have been compared with the particle swarm optimization technique. Global minimum for all the examples from grey wolf optimizer was obtained with seven wolves in a pack and 2000 iterations. Inversion was initially performed on thin dykes for noise‐free and noise‐corrupted (up to 20% random noise) synthetic data sets. The inversion on a single thin dyke was performed with a different search space. The results demonstrate that, compared with particle swarm optimization, the grey wolf optimizer is less sensitive to search space variations. Inversion of noise‐corrupted data shows that grey wolf optimizer has a better capability in handling noisy data as compared to particle swarm optimization. Practical applicability of the grey wolf optimizer has been demonstrated by adopting four profiles (i.e. surface magnetic, airborne magnetic, gravity and self‐potential) from the published literature. The grey wolf optimizer results show better data fit than the particle swarm optimizer results and match well with borehole data.
Glycyrrhetic Acid 3‐O‐Mono‐β‐d‐glucuronide (GAMG): An Innovative High‐Potency Sweetener with Improved Biological Activities
Authors: Guo Lichun , Katiyo Wendy , Lu Liushen , Zhang Xuan , Wang Mingming , Yan Jiai , Ma Xiaoyun , Yang Ruijin , Zou Long , Zhao Wei 
Published: May 2018

AbstractGlycyrrhetic acid 3‐O‐mono‐β‐d‐glucuronide (GAMG) is an important derivative of glycyrrhizin (GL) and has attracted considerable attention, especially in the food and pharmaceutical industries, due to its natural high sweetness and strong biological activities. The biotransformation process is becoming an efficient route for GAMG production with the advantages of mild reaction conditions, environmentally friendly process, and high production efficiency. Recent studies showed that several β‐glucuronidases (β‐GUS) are key GAMG‐producing enzymes, displaying a high potential to convert GL directly into the more valuable GAMG and providing new insights into the generation of high‐value compounds. This review provides details of the structural properties, health benefits, and potential applications of GAMG. The progress in the development of the biotransformation processes and fermentation strategies to improve the yield of GAMG is also discussed. This work further summarizes recent advances in the enzymatic synthesis of GAMG using β‐GUS with emphasis on the physicochemical and biological properties, molecular modifications, and enzymatic strategies to improve β‐GUS biocatalytic efficiencies. This information contributes to a better framework to explore production and application of bioactive GAMG.
Nonthermal Processes for Shelf‐Life Extension of Seafoods: A Revisit
Authors: Olatunde Oladipupo Odunayo , Benjakul Soottawat 
Published: May 2018

AbstractFor the past two decades, consumer demand for minimally processed seafoods with good sensory acceptability and nutritive properties has been increasing. Nonthermal food processing and preservation technologies have drawn the attention of food scientists and manufacturers because nutritional and sensory properties of such treated foods are minimally affected. More importantly, shelf‐life is extended as nonthermal treatments are capable of inhibiting or killing both spoilage and pathogenic organisms. They are also considered to be more energy‐efficient and to yield better quality when compared with conventional thermal processes. This review provides insight into the nonthermal processing technologies currently used for shelf‐life extension of seafoods. Both pretreatments such as acidic electrolyte water and ozonification and processing technologies, including high hydrostatic pressurization, ionizing radiation, cold plasma, ultraviolet light, and pulsed electric fields, as well as packaging technology, particularly modified atmosphere packaging, have been implemented to lower the microbial load in seafood. Thus, those technologies may be the ideal approach for the seafood industry, in which prime quality is maintained and safety is assured for consumers.
Potential Functional Byproducts from Guava Purée Processing
Authors: Lim Si Yi , Tham Paik Yean , Lim Hilary Yi Ler , Heng Wooi Shin , Chang Ying Ping 
Published: May 2018

AbstractThe valorization of guava waste requires compositional and functional studies. We tested three byproducts of guava purée processing, namely refiner, siever, and decanter. We analyzed the chemical composition and quantified the prebiotic activity score and selected carbohydrates; we also determined the water holding (WHC), oil holding (OHC), cation exchange capacities, bile acid binding, and glucose dialysis retardation (GDR) of the solid fraction and the antioxidative and α‐amylase inhibitory capacities (AIC) of the ethanolic extract. Refiner contained 7.7% lipid, 7.08% protein and a relatively high phytate content; it had a high prebiotic activity score and possessed the highest binding capacity with deoxycholic acid. Siever contained high levels of low molecular weight carbohydrates and total tannin but relatively low crude fiber and cellulose contents. It had the highest binding with chenodeoxycholic acid (74.8%), and exhibited the highest 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) radical scavenging capacity. Decanter was rich in cellulose and had a high prebiotic activity score. The WHC and OHC values of decanter were within a narrow range and also exhibited the highest binding with cholic acid (86.6%), and the highest values of GDR and AIC. The refiner waste could be included in animal feed but requires further processing to reduce the high phytate levels. All three guava byproducts had the potential to be a source of antioxidant dietary fiber (DF), a finding that warrants further in vivo study.Practical ApplicationTo differing extents, the guava byproducts exhibited useful physicochemical binding properties and so possessed the potential for health‐promoting activity. These byproducts could also be upgraded to other marketable products so the manufacturers of processed guava might be able to develop their businesses sustainably by making better use of them.
Characterization of Nanofibrillated Cellulose Produced by Different Methods from Cabbage Outer Leaves
Authors: Khukutapan Donnapa , Chiewchan Naphaporn , Devahastin Sakamon 
Published: May 2018

AbstractThe potential use of cabbage outer leaves as a starting material for the production of nanofibrillated cellulose (NFC) was investigated. Chemical‐free pretreatment methods, namely, autoclaving, ultrasonication (US), and high‐shear homogenization (HS), were applied to remove noncellulosic components from cabbage cell walls prior to defibrillation, which was conducted by subjecting a pretreated sample to HS and then high‐pressure homogenization. The sample undergone autoclaving at 130 °C for 2 hr was noted to contain a significantly higher cellulose content (36.5% dry mass) compared with the fresh leaves (12.48% dry mass). This led to an increase in the crystallinity index (CI) of the autoclaved cabbages from 30.8% to 50.7%. Further increase in the cellulose content (47.0% to 49.2% dry mass) was observed when subjecting the autoclaved sample to either US at 37 kHz for 1 hr, HS at 3800 × g for 15 min or HS followed by US at the aforementioned conditions. After pretreatment and defibrilllation, a suspension of NFC with the diameters of 4 to 50 nm was obtained, with the CI of 59.1% to 66.7%. Such a suspension exhibited a gel‐like behavior with tan δ in the range of 0.12 to 0.13; the suspension exhibited a similar behavior to that prepared by the conventional chemical pretreatment method.Practical ApplicationNFC could be produced from cabbage outer leaves, which are an abundantly available by‐product of a vegetable processing plant, via the combined hydrothermal and mechanical pretreatment without the use of any chemicals. This chemical‐free preparation process is highly desirable as it leaves no residues in the product and causes no chemical waste that needs to be treated. Cabbage‐based NFC also exhibits similar characteristics to that prepared via a chemically treated route.
Evaluation of Antioxidant Properties, Phenolic Compounds, Anthelmintic, and Cytotoxic Activities of Various Extracts Isolated from Nepeta cadmea: An Endemic Plant for Turkey
Authors: Kaska Arzu , Deniz Nahide , Çiçek Mehmet , Mammadov Ramazan 
Published: May 2018

AbstractNepeta cadmea Boiss. is a species endemic to Turkey that belongs to the Nepeta genus. Several species of this genus are used in folk medicine. This study was designed to investigate the phenolic compounds, antioxidant, anthelmintic, and cytotoxic activities of various extracts (ethanol, methanol, acetone, and water) of N. cadmea. The antioxidant activities of these extracts were analyzed using scavenging methods (DPPH, ABTS, and H2O2 scavenging activity), the β‐carotene/linoleic acid test system, the phosphomolybdenum method, and metal chelating activity. Among the 4 different extracts of N. cadmea that were evaluated, the water extract showed the highest amount of radical scavenging (DPPH, 25.54 μg/mL and ABTS, 14.51 μg/mL) and antioxidant activities (β‐carotene, 86.91%). In the metal chelating and H2O2 scavenging activities, the acetone extract was statistically different from the other extracts. For the phosphomolybdenum method, the antioxidant capacity of the extracts was in the range of 8.15 to 80.40 μg/mg. The phenolic content of the ethanol extract was examined using HPLC and determined some phenolics: epicatechin, chlorogenic, and caffeic acids. With regard to the anthelmintic properties, dose‐dependent activity was observed in each of the extracts of N. cadmea. All the extracts exhibited high cytotoxic activities. The results will provide additional information for further studies on the biological activities of N. cadmea, while also helping us to understand the importance of this species. Furthermore, based on the results obtained, N. cadmea may be considered as a potentially useful supplement for the human diet, as well as a natural antioxidant for medicinal applications.Practical ApplicationThe plants of the Nepeta genus have been extensively used as traditional herbal medicines. Nepeta cadmea Boiss., one of the species belonging to the Nepeta genus, is a species endemic to Turkey. In our study, we demonstrated the antioxidant capacities, total phenolic, flavonoid, tannin content, anthelmintic, and cytotoxic activities of various extracts of Nepeta cadmea. The present study could well supply valuable data for future investigations and further information on the potential use of this endemic plant for humans, in both dietary and pharmacological applications.
Clinical Predictors of Risk for Decreased Cardiac Tissue Perfusion After Percutaneous Coronary Intervention: A Retrospective Cohort Study
Authors: Monteiro Moreira Francine , Cristina Dias Cunha Nascimento Teresa , Murata Murakami Beatriz , Cristina Bergamasco Ellen , Takao Lopes Camila , Ribeiro dos Santos Eduarda 
Published: May 2018

OBJECTIVETo establish clinical predictors of risk for decreased cardiac tissue perfusion (DCTP) after percutaneous coronary intervention (PCI).METHODSData on demographic, anthropometric, clinical, and procedural variables were collected as explanatory from a database of 1,542 adult patients undergoing PCI. A diagnosis of periprocedural myocardial infarction was used to confirm DCTP. A multivariate logistic regression determined the predictors of DCTP.RESULTSThe independent predictors of risk for DCTP were age (OR = 1.02, CI 95% = 1.01–1.03, p = .008), multivessel disease (OR = 1.79, CI 95% = 1.30–2.46, p <.001) and intraprocedural lesion complications (OR = 4.56, CI 95% = 3.03–6.87, p <.001).CONCLUSION AND IMPLICATIONS FOR NURSING PRACTICEThese results increase the level of evidence of risk for DCTP by refining its risk factors and can support nurses’ clinical judgment.
Laparoscopic total gastrectomy for remnant gastric cancer: A single‐institution experience
Authors: Booka Eisuke , Kaihara Masaki , Mihara Koki , Nishiya Shin , Handa Kan , Ito Yasuhiro , Shibutani Shintaro , Egawa Tomohisa , Nagashima Atsushi 
Published: May 2018

AbstractIntroductionThe incidence of remnant gastric cancer is increasing because of past use of subtotal gastrectomy to treat peptic ulcer and increased survival rates after radical gastrectomy for gastric cancer. The feasibility and advantages of laparoscopic total gastrectomy (LTG) for remnant gastric cancer remain unclear. Therefore, we aimed to investigate the safety, feasibility, and clinical short‐term outcomes of LTG for remnant gastric cancer.MethodsPatients who underwent completion total gastrectomy for remnant gastric cancer between April 2007 and October 2017 were divided into two groups: the open total gastrectomy (OTG) group and the LTG group. Clinicopathological data and short‐term outcomes were analyzed.ResultsA total of 31 remnant gastrectomies (23 OTG, 8 LTG) were performed. Blood loss was significantly lower in the LTG group than in the OTG group (135.5 vs 568.3 mL, P = 0.013). However, there was no significant difference in the operation time, days to food intake, or length of hospital stay between the two groups. Additionally, there was no significant difference in the postoperative complications, number of retrieved lymph nodes, or pathological findings. Two LTG patients (25.0%) required conversion to open surgery. There was no mortality in either group.ConclusionsLTG for remnant gastric cancer can be a safe treatment option and may have an advantage of less blood loss than OTG.
Laparoscopic nephrectomy in a patient with severe scoliosis: A case report
Authors: Tamura Daichi , Ito Ayato , Kikuchi Daichi , Tsuyukubo Takashi , Kato Renpei , Kato Yoichiro , Konari Susumu , Omori So , Obara Wataru 
Published: May 2018

AbstractAlthough the role of laparoscopic nephrectomy (LN) has been established, few studies have reported cases of LN in individuals with scoliosis. Here we report a case of right LN in a patient with severe right convex scoliosis. A 26‐year‐old man presented with a fever. His medical history comprised severe right convex lumbar scoliosis. CT revealed right hydronephrosis and right kidney stones. Pyelonephritis requiring nephrectomy was diagnosed. Right LN was feasible with elaborate perioperative care. The postoperative course was uneventful with no relapse of urinary tract infection.
Laparoscopic abdominoperineal resection with lateral lymph node dissection for advanced rectal and prostate cancer with synchronous lateral lymph node metastases
Authors: Ishikawa Takahisa , Homma Shigenori , Nishikawa Makoto , Nakamoto Hiroki , Yokoyama Ryoji , Taketomi Akinobu 
Published: May 2018

AbstractHere we report a case of advanced rectal and prostate cancer with synchronous lateral lymph node (LLN) metastases that was treated with laparoscopic surgery. A 71‐year‐old man presented with fecal occult blood and was diagnosed with rectal cancer. A metastatic right LLN was suspected after CT examination of a 19‐mm lymph node (proximal internal iliac artery region) and a 13‐mm lymph node (distal internal iliac artery region) in the right lateral region. We planned neoadjuvant chemotherapy to suppress local and distant recurrence. This treatment decreased the size of the primary rectal tumor. We performed laparoscopic abdominoperineal resection and right LLN dissection. The histopathological diagnosis was LLN metastases from the rectal and prostate cancers. It is rare for synchronous metastases from rectal and prostate cancers to be observed in the LLN. It may be difficult to determine an appropriate treatment strategy in cases like this.
Synthesis and biological evaluation of novel N‐aryl‐ω‐(benzoazol‐2‐yl)‐sulfanylalkanamides as dual inhibitors of α‐glucosidase and protein tyrosine phosphatase 1B
Authors: Wang Mei‐Yan , Cheng Xian‐Chao , Chen Xiu‐Bo , Li Yu , Zang Lan‐Lan , Duan Yu‐Qing , Chen Ming‐Zhu , Yu Peng , Sun Hua , Wang Run‐Ling 
Published: May 2018

α‐Glucosidase is known to catalyze the digestion of carbohydrates and release free glucose into the digestive tract. Protein tyrosine phosphatase 1B (PTP1B) is engaged in the dephosphorylation of the insulin receptor and regulation of insulin sensitivity. Therefore, dual antagonists by targeting both α‐glucosidase and PTP1B may be potential candidates for type 2 diabetes therapy. In this work, three series of novel N‐aryl‐ω‐(benzoazol‐2‐yl)‐sulfanylalkanamides were synthesized and assayed for their α‐glucosidase and PTP1B inhibitory activities, respectively. Compound 3l, exhibiting the most effective α‐glucosidase inhibitory activity (IC50 = 10.96 μm (3l), IC50 = 51.32 μm (Acarbose), IC50 = 18.22 μm (Ursolic acid)) and potent PTP1B inhibitory activity (IC50 = 13.46 μm (3l), IC50 = 14.50 μm (Ursolic acid)), was identified as a novel dual inhibitor of α‐glucosidase and PTP1B. Furthermore, 3l is a highly selective PTP1B inhibitor because no inhibition was showed by 3l at 100 μm against PTP‐MEG2, TCPTP, SHP2, or SHP1. Subsequent kinetic analysis revealed 3l inhibited α‐glucosidase in a reversible and mixed manner. Molecular docking study indicated that hydrogen bonds, van der Waals, charge interactions and Pi‐cation interactions all contributed to affinity between 3l and α‐glucosidase/PTP1B.