bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perioperative Use of Systemic Steroids Within Otolaryngology–Head and Neck Surgery: Evidence‐Based Guidance for Clinicians
Authors: Ikeda Allison K. , Gray Raluca , Lee Victoria , Dixon Johns James , Briggs Selena , Raol Nikhila R. , Megwalu Uchechukwu C. , Joe Stephanie , Garritano Frank , Brenner Michael J. , McCoul Edward D. 
Published: December 2024

AbstractObjectiveTo review and synthesize the available evidence for use of perioperative systemic steroids for otolaryngologic surgical procedures.Data SourcesA comprehensive literature review with evidence‐informed recommendations.Review MethodsDatabases were queried for medical subject heading terms and keywords related to perioperative systemic corticosteroids use for comprehensive otolaryngology and subspecialty procedures including otologic, sinonasal, sleep, laryngeal, head and neck, facial plastics, and pediatric surgery. Perioperative period included preoperative (up to 7 days prior to surgery), intraoperative (on the day of surgery), and postoperative (initiated within 24 hours after surgery) timeframes.ConclusionsEvidence from clinical practice guidelines, systematic reviews, and original research studies supports perioperative systemic corticosteroid use for specific otolaryngologic indications. Numerous studies support perioperative steroid use for nausea, vomiting, or edema in tonsillectomy, rhinoplasty, and thyroidectomy, although formal guideline recommendations are limited. Strong evidence supports perioperative steroid use before and after endoscopic sinus surgery for chronic rhinosinusitis with polyposis and fungal sinusitis. Evidence of benefit is sparse or absent on systemic perioperative steroid use for the middle and inner ear, laryngeal, salivary gland surgery, and reconstructive facial plastic surgery.Implications for PracticeAlthough perioperative administration of systemic steroids is routinely performed for many otolaryngologic surgeries, high‐level evidence is limited to specific contexts. Evidence supports the benefit for reducing nausea, vomiting, or edema for several otolaryngologic procedures, as well as for either chronic rhinosinusitis with polyposis or fungal sinusitis. However, these benefits need to be weighed against risks, and further investigations are needed to define the role for perioperative steroids in otolaryngology.
Standardized List Evaluating Apnea (SLEAP): A Comprehensive Survey to Define the Quality of Life in OSA
Authors: Abdelwahab Mohamed , Saltychev Mikhail , Lechner Matt , Adibi Elahe , Wadsworth Elizabeth Walker , Fleury Thomaz , Rakha Abdelwahab , Khafagy Yasser , Abdelfattah Ahmed , Al‐Sayed Ahmed A. , Chou Courtney , Ali Ban , Liu Stanley , Kushida Clete , Capasso Robson 
Published: December 2024

AbstractObjectiveTo develop and validate a patient‐reported outcome measure (PROM) to evaluate the quality of life (QoL) among patients with obstructive sleep apnea (OSA).Study DesignA prospective cohort study.SettingsTertiary referral center.MethodsWe developed a 15‐item English questionnaire that was administered to 176 adults with OSA and 22 adult controls without symptoms of OSA in a tertiary sleep surgery clinic between June 2021 and December 2021. The internal consistency and test‐retest reliability were measured using the Cronbach's α and the intraclass correlation coefficient, respectively. The 2‐sample Wilcoxon rank‐sum (Mann‐Whitney) test was applied to compare the 2 groups. Convergent validity of the test scores of the questionnaire was compared to previously validated outcome measures and objective sleep study outcomes using the Spearman correlation coefficient.ResultsOf the 198 respondents (176 cases and 22 controls); 71% were men and 29% were women. The internal consistency was excellent with the α of .92 (lower 95% confidence limit of 0.90). All the test‐retest correlations were positive, significant, and strong ranging from 0.50 to 0.90. The differences between cases and controls were statistically significant for all the items and for the total score. The total score of the questionnaire with the Epworth Sleepiness Scale and objective OSA measures was moderate to strong.Conclusions and RelevanceThe new tool provides a validated PROM to evaluate the QoL among OSA patients specifically, with excellent internal consistency, reasonable test‐retest reliability, discriminant validity, and construct validity.Level of EvidenceLevel 4.
Study on mechanical performance of carbon fiber reinforced polyetherketoneketone prepreg and its composites prepared by slurry method
Authors: Cheng Dongcai , Shen Wensi , Chen Yuxi , Zhang Weijian , Huang Yuexing , He Yuzhao , Yu Lichao , Shen Linfeng 
Published: December 2024

AbstractThe increasing demand for high‐performance materials in aerospace, automotive, and industrial applications has driven research into carbon fiber reinforced polyetherketoneketone (CF/PEKK) composites. This study introduces a novel slurry method for preparing CF/PEKK prepregs and investigates the impact of fiber surface treatments—desized and non‐desized carbon fibers—on the mechanical properties of the resulting composites. CF/PEKK prepregs were successfully prepared by dispersing PEKK powder in deionized water to create a slurry, which was used to impregnate carbon fibers. After hot‐pressing, mechanical testing revealed that composites with desized fibers outperformed those with non‐desized fibers in tensile strength (3.29%), flexural strength (22.12%), and interlaminar shear strength (18.29%). Furthermore, desized composites exhibited improved impact toughness (24.29%) and reduced fiber pull‐out during tensile testing. Scanning electron microscopy (SEM) analysis confirmed enhanced fiber‐matrix bonding in desized composites, with fewer voids and better fiber dispersion. These findings underscore the effectiveness of the slurry method and fiber desizing in improving the mechanical performance of CF/PEKK composites, offering potential for advanced applications in high‐performance sectors.Highlights
Thermoplastic CF/PEKK prepregs successfully developed using slurry method.
Novel slurry method enhances prepreg quality in CF/PEKK composites.
Desized carbon fibers improve interfacial bonding and strength.
Desized composites exhibit reduced fiber pull‐out during tensile testing.
Understanding the dielectric properties of silicone rubber‐BN nanocomposites under DC voltage
Authors: Krupanandam Ganesan , Dhivakar J Manoj , Kornhuber Stefan , Sarathi Ramanujam 
Published: December 2024

AbstractThe present study explores the dielectric and structural properties of silicone rubber composites with low‐weight percentages of boron nitride (BN) fillers aimed at insulation applications. The incorporation of BN fillers into the silicone rubber matrix significantly enhances the glass transition temperature (Tg), melting temperature (Tm), and crystallization temperature (Tc). Notably, the dielectric constant increases while the loss factor remains minimal with a low concentration of BN fillers with silicone rubber matrix. J–V characteristics from space charge limited current (SCLC) measurements were employed to evaluate trap density. The addition of 3 wt% BN filler notably improves the crossover voltage and trap density in the silicone rubber matrix. A strong correlation has been observed between trap density values derived from SCLC measurements and surface potential decay experiments. Furthermore, the SCLC measurements at different temperatures exhibit an Arrhenius behavior, providing insights into the charge transport and trapping mechanisms. Overall, the experiment results indicate that the inclusion of 3 wt % of BN filler has significant improvement in dielectric as well as charge trap characteristics.Highlights
BN filler impacts permittivity and tan (δ) based on concentration levels.
Differential scanning calorimetry shows crystallinity changes with increased BN filler in silicone rubber.
Surface potential relates to J–V characteristics, following SCLC mechanism.
Arrhenius relation to temperature‐based SCLC shows thermally activated conduction.
Trap density trends align in SCLC and surface potential decay methods.
Synergistic Effect of Ag, Sb Dual‐Cation Substitution on Cu2ZnSn (S, Se)4 High‐Efficiency Solar Cells
Authors: Wang Tianyue , Sui Yingrui , Miao Chang , Cui Yue , Wang Zhanwu , Yang Lili , Wang Fengyou , Liu Xiaoyan , Yao Bin 
Published: December 2024

ABSTRACTThe poor crystal quality inside an absorber layer and the presence of various harmful defects are the main obstacles restricting the properties of Cu2ZnSn (S, Se)4 (CZTSSe) thin‐film solar cells. Cation doping has attracted considerable research attention as a viable strategy to overcome this challenge. In this paper, based on Sb‐substituted CZTSSe system, we prove that Ag partially substituting Cu may be a feasible strategy. After a series of characterization of the films, it was discovered that the crystal quality and crystallinity of the films were further improved by introducing Ag into Cu2Zn(Sb, Sn) (S, Se)4 (CZTSSSe), and the concentrations of CuZn accepter defects and 2[CuZn + SnZn] defect clusters were effectively inhibited. At the same time, the carrier concentration is increased. The results show that when the Ag doping ratio is 15%, the photovoltaic conversion efficiency (PCE) reaches 8.34%, compared with the single‐doped Sb element, the efficiency is increased by 24%. For the first time, this study investigates the collaborative effect of Sb, Ag dual‐cation substitution in CZTSSe. The solar cell performance enhancement mechanism offers new potential for the advancement of CZTSSe thin‐film solar cell technology in the future.
Registration of four durum wheat lines carrying Sr13 alleles for resistance to stem rust
Authors: Klindworth Daryl L. , Rouse Matthew N. , Olivera Pablo D. , Jin Yue , Chu Chenggen , Friesen Timothy L. , Zhong Shaobin , Faris Justin D. , Fiedler Jason D. , Haugrud Amanda R. Peters , Gu Yong Q. , Elias Elias M. , Liu Shuyu , Cai Xiwen , Xu Steven S. 
Published: December 2024

AbstractFour durum wheat (Triticum turgidum ssp. durum) lines Rusty‐KLB (Reg. no. GP‐1098, PI 705448), Rusty‐14803 (Reg. no. GP‐1097, PI 705447), Rusty‐ST464C1 (Reg. no. GP‐1099, PI 705449), and CAT‐A1 (Reg. no. GP‐1096, PI 705446), which carry stem rust resistance gene Sr13 alleles Sr13a, Sr13b, Sr13c, and Sr13d, respectively, are released by USDA‐ARS. These alleles originated from cultivated emmer wheat (T. turgidum ssp. dicoccum) landrace Khapli (CItr 4013), T. turgidum ssp. polonicum accession CItr 14803, durum landrace ST464 (PI 191365), and durum line Camadi Abdu tipo #103 (PI 192168), respectively. Rusty‐KLB, Rusty‐14803, and Rusty‐ST464C1 are near‐isogenic lines with the pedigrees Rusty*7/KL‐B, Rusty*4/3/Rusty/CItr 14803//2*Rusty, and Rusty*7/ST464‐C1, respectively. KL‐B, ST464‐C1, and CAT‐A1 are monogenic lines with the pedigrees Marruecos 9623//Khapli/Marruecos 9623, Marruecos 9623*2/ST464, and Marruecos 9623*2/Camadi Abdu tipo #103, respectively. Sr13 can be detected by perfect markers including Kompetitive allele specific polymerase chain reaction (KASP) marker KASPSr13 and semi‐thermal asymmetric reverse polymerase chain reaction (STARP) markers rwgsnp37. Specific alleles can be identified via STARP markers rwgsnp38, rwgsnp39, and rwgsnp40. The Sr13 alleles provide a moderate level of resistance, typically an infection type 2, to a broad spectrum of stem rust races. Sr13c was effective against all 15 stem rust races tested while Sr13a was ineffective only against race TCMJC. Sr13b was ineffective against JRCQC, QCCJC, QFCSC, and TTRTF. Sr13d is notable in being the only Sr13 allele ineffective to TTKSK (Ug99) and TKTTF. These lines are useful for studying the host‐stem rust pathogen interactions, identifying new genes, and breeding durum and bread wheat cultivars with stem rust resistance.
Intergenerational Care in Local, Long‐Distance, and Transnational Families: The Role of Geographical Distance and Cross‐Border Separation on Subjective Care Burden
Authors: Schiefer David , Nowicka Magdalena 
Published: December 2024

ABSTRACTTransnational family research documented well the challenges that migrated adult children experience when they want to provide care to their stayed‐behind families. Yet similar results are provided by research on long‐distance carers who are not international migrants. So far, it remains unclear how challenges of providing support to family members relate to the geographical distance between them, or rather to the cross‐border character of migration, it is when the (expected) caregivers and care‐receivers live in two different nation‐states. This article thus investigates the role of geographical distance and cross‐border separation on perceived intergenerational care burden of residents in Germany who feel in responsibility or provide care to their parents. We use data from a survey with 2900 migrant and nonmigrant residents in Germany. Findings reveal that geographical distance and cross‐border separation constitute two independent, accumulating stressors for burden experienced by individuals caring for their parents. Furthermore, we can show that the link between cross‐border separation and intergenerational care burden is due to increased time and financial costs but particularly due to legal restrictions to mobility such as non‐German citizenship or visa restrictions. The study represents one of the initial attempts to elucidate the mechanisms underlying distance and cross‐border separation in transnational intergenerational care, demonstrating that general theoretical frameworks for understanding burden in intergenerational care relationships can be applied to cross‐border family constellations.
The Nexus Between Traditional Chinese Medicine and Immunoporosis: Implications in the Treatment and Management of Osteoporosis
Authors: Ding Xiaolei , Yang Jie , Wei Yuchi , Wang Mingyue , Peng Zeyu , He Rong , Li Xiangyan , Zhao Daqing , Leng Xiangyang , Dong Haisi 
Published: December 2024

ABSTRACTOsteoporosis (OP) is a globally prevalent bone disease characterized by reduced bone mass and heightened fracture risk, posing a significant health and economic challenge to aging societies worldwide. Osteoimmunology—an emerging field of study—investigates the intricate relationship between the skeletal and the immune systems, providing insights into the immune system's impact on bone health and disease progression. Recent research has demonstrated the essential roles played by various immune cells (T cells, B cells, macrophages, dendritic cells, mast cells, granulocytes, and innate lymphoid cells) in regulating bone metabolism, homeostasis, formation, and remodeling through interactions with osteoclasts (OC) and osteoblasts (OB). These findings underscore that osteoimmunology provides an essential theoretical framework for understanding the pathogenesis of various skeletal disorders, including OP. Traditional Chinese medicine (TCM) and its active ingredients have significant clinical value in OP treatment. Unfortunately, despite their striking multieffect pathways in the pharmacological field, current research has not yet summarized them in a comprehensive and detailed manner with respect to their interventional roles in immune bone diseases, especially OP. Consequently, this review addresses recent studies on the mechanisms by which immune cells and their communication molecules contribute to OP development. Additionally, it explores the potential therapeutic benefits of TCM and its active components in treating OP from the perspective of osteoimmunology. The objective is to provide a comprehensive framework that enhances the understanding of the therapeutic mechanisms of TCM in treating immune‐related bone diseases and to facilitate the development of novel therapeutic strategies.
Cupressus torulosa, a Source of Antioxidant Polyphenols: An Analytical and Pharmacological Study
Authors: Khanna Radhika , Chitme H. R. , Bhadoriya Khushaboo , Varshney V. K. 
Published: December 2024

ABSTRACTIntroductionCupressus torulosa (family Cupressaceae), widely distributed in the northwestern Himalayan region of India, is a coniferous aromatic tree traditionally used for its aerial parts. Its needles are renowned for their anti‐inflammatory, anticonvulsant, antimicrobial, and wound‐healing properties. Antioxidants from this plant are vital in combating oxidative stress, which are implicated in these diseases.MethodsThis study employed a range of methods, including in vitro, in vivo, and ex vivo assays; biochemical estimations such as Total Phenolics Content and Total Flavonoids Content; and UPLC‐QTOF‐MS analysis, to evaluate the antioxidant potential of Cupressus torulosa needles.ResultsInitial screenings demonstrated promising antioxidant activity of 25% aqueous methanol extract of the needles, with SGOT and SGPT values of 55.28±57.07 and 52.27±19.50 IU/L, respectively, when compared to the positive control glibenclamide. Fractionation of the extract into ethyl acetate and butanol fractions revealed that the ethyl acetate fraction showed notable activity, with an EC50 value of 85.6 μg/mL in the DPPH assay, indicating effective free radical scavenging and reduced oxidative damage. UPLC‐QTOF‐MS characterization of ethyl acetate fraction in negative ion mode identified 34 metabolites, including 10 key antioxidant compounds.ConclusionThese findings underscore C. torulosa’s potential as a source of bioactive antioxidants, highlighting its value for pharmaceutical and nutraceutical applications. The research provides a foundation for further isolation, characterization, and clinical testing of these compounds, enhancing our understanding of natural antioxidants in addressing oxidative stress‐related conditions.
Hemoptysis caused by bronchial artery‐pulmonary artery fistula complicated with Dieulafoy disease: A case report
Authors: Lv Chongqing , Feng Tao , Wang Shishou , Lin Chen 
Published: December 2024

AbstractBronchial artery‐pulmonary artery fistula (BPF) is a rare vascular malformation of the bronchial arteries, associated with congenital heart disease, pulmonary hypertension, or pulmonary infections. It typically presents in adulthood and has a low incidence. Another rare vascular anomaly, bronchial Dieulafoy disease (BDD), is characterized by an abnormally developed artery within the submucosa of the bronchial tree. This condition is thought to arise from a combination of congenital dysplasia and chronic airway inflammation or injury. Both BPF and BDD are uncommon causes of hemoptysis, and their simultaneous occurrence is exceptionally rare. This report discusses a case of BPF complicated by BDD in a patient who presented with recurrent hemoptysis. The diagnosis was established through bronchial artery angiography, bronchoscopy, and surgical pathology. By examining the clinical features, imaging findings, and diagnostic criteria of these conditions, this case report aims to enhance clinicians' understanding of cryptogenic hemoptysis and provide valuable insights for clinical practice.
A case of silicosis with Mycobacterium avium infection relapsed with lymphadenitis 1 year after the completion of initial treatment
Authors: Hatakeyama Taku , Yokoo Keiki , Tatsuhige Ryota , Nagao Takayuki , Kikuchi Koki , Ota Satoshi , Yamada Gen , Chiba Hirofumi 
Published: December 2024

AbstractA 71‐year‐old man with silicosis was treated for Mycobacterium avium infection. Antimycobacterial treatment for M. avium was terminated 1 year after a negative test result for the bacteria on sputum examination. One year following the treatment, the patient developed pneumonitis. In the sputum culture, growth of M. avium was not detected. Pneumonitis did not improve despite sufficient antibacterial therapy. Chest computed tomography scan revealed aggravated shadows of pneumonitis and swelling of supraclavicular lymph nodes. A lymph node biopsy was performed, and polymerase chain reaction testing revealed M. avium infection. We diagnosed the patient with pneumonitis and lymphadenitis due to recurrent M. avium infection. Antimycobacterial treatment with rifampicin, ethambutol, clarithromycin, and amikacin was initiated. Pneumonitis and the general status of the patient improved following the treatment. Lymphadenitis is rare in adults in the absence of any immunodeficiency condition. We speculate that silicosis is a risk factor for mycobacterial infection recurrence.
A case of pulmonary vein thrombosis with transient ischemic attacks diagnosed by contrast‐enhanced computed tomography
Authors: Ogata Yoshimasa , Aita Keisuke , Maeda Juri , Shiragami Risa , Hagiya Masaaki , Shuto Kiyohiko , Nakamura Fumitaka , Yamaguchi Masao 
Published: December 2024

AbstractPulmonary vein thrombosis (PVT) is rarer than pulmonary artery thrombosis (PAT). PVT is potentially fatal but is often overlooked due to its nonspecific symptoms. We present a case with PVT accompanied by paroxysmal atrial fibrillation. The symptoms were limited to transient ischemic attacks. Contrast‐enhanced computed tomography (CT), which showed a thrombus in the right pulmonary vein trunk, was useful in diagnosing PVT. After switching the patient's anticoagulant from dabigatran etexilate to apixaban, the thrombus disappeared within 5 months. Contrast‐enhanced CT is a useful and common tool for diagnosis and follow‐up of PVT.
High Performance Bounded Finite Time Control for Linear Systems With Input Saturation
Authors: Ma Wenyu , Liu Guangyu 
Published: December 2024

ABSTRACTReal‐world dynamical controlled systems are often subject to input saturation due to the physical constraints of actuators. This causes the response performance of the system to be degraded. To this end, we propose a high‐performance bounded finite time control (HP‐BFTC) method based on sliding mode control for finite time tracking of linear systems with input saturation. In this method, a novel concept of rate regulation finite‐time stability is proposed to achieve better steady‐state performance. A bounded controller based on sliding mode control is proposed to achieve finite‐time stability in rate regulation, wherein a finite time approach rate based on an inverse tangent function is presented to alleviate chattering caused by sign function, and two control parameters are introduced to improve response performance. The rate regulation finite‐time stability of the system is proved in the estimated domain of attraction. In addition, a parameter tuning principle is given to enhance the response performance of the closed‐loop system in transient and steady state. The superiority of the proposed method in performance is verified by a case study.
Superior Salting‐Out of MgSO4 to Improve the Synthesis of 5‐Hydroxymethylfurfural
Authors: Cao Zhi , Liu Chao , Cao Haitao , Fan Zhongxiang , Shi Yixiang , Shen Tao 
Published: December 2024

AbstractThe effect of salts on the 5‐hydroxymethylfurfural (HMF) synthesis over the catalyst of AlCl3‐HCl was investigated. An unprecedented R (distribution coefficient) value of 30.48 was achieved in the H2O/THF system when MgSO4 was used as a salting‐out agent. Results indicated that the excellent salting‐out effect of MgSO4 on HMF was attributed to the synergistic effect of Mg2+ and SO42−. MgSO4 showed more efficiency on the HMF synthesis than other salts in the ChCl‐H2O/THF biphasic system. A 78.1% yield of HMF was achieved from glucose under optimal conditions, and higher than 95.0% of the produced HMF was partitioned into the organic phase due to the excellent salting‐out effect of MgSO4. During the recyclability of the aqueous phase, a remarkably high yield of HMF (78.0%) and conversion of glucose (93.8%) were achieved even after 10 cycles. The MgSO4 also showed efficiency to improve the synthesis of HMF from other sugars. Finally, the salting‐out effect of MgSO4 on sugar dehydration was investigated in other biphasic systems, and the yield of HMF showed an obvious increase compared with the literature reports.