bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clothes, condoms, and customer satisfaction: The effect of employee mere presence on customer satisfaction depends on the shopping situation
Authors: Otterbring Tobias , Lu Chaoren 
Published: April 2018

AbstractFew studies have examined how customers respond to the mere presence of others in the shopping environment, and only one article (Söderlund, ) has investigated the unique impact that employee presence has on key customer outcomes. Söderlund () found that customers entering a store with an employee present (vs. absent) reported significantly higher levels of customer satisfaction, with their increased levels of pleasurable feelings mediating this effect. However, similar to the majority of theorizing on customer satisfaction, that article was restricted to data collected in a Western society. Given the rapid economic growth in many Asian regions, there is a need to examine the applicability of such Western‐based findings from an Asian perspective, and hence include participants from Eastern societies. Accordingly, the present research investigated whether Söderlund's () results could be replicated among Asian customers. The current work also sought to extend prior findings beyond pleasure and customer satisfaction while simultaneously documenting a boundary condition for the hitherto positive employee mere presence effects. To this end, two between‐subjects experiments with a total sample of 498 Chinese customers were conducted. Study 1, which involved a shopping situation in a clothing store, replicated Söderlund's () main results and further found that employee mere presence (vs. absence) had a significant positive impact on customers’ loyalty intentions. These results were reversed in Study 2, in which the shopping situation involved the purchase of an embarrassing product. Under such circumstances, employee presence (vs. absence) consistently produced negative effects on customers’ levels of pleasure, satisfaction, and loyalty intentions.
Efficient Charge Transport in Disordered Conjugated Polymer Microstructures
Authors: Noriega Rodrigo 
Published: April 2018

AbstractA new class of conjugated polymers with high charge mobilities exhibits the apparently conflicting morphological features of increased order at the molecular scale while lacking long‐range order and crystallinity. To exploit their unique properties, mechanistic insights for charge transport events taking place from the molecular to the device scale must be uncovered. Thus, a central contributor to the continued progress in conjugated optoelectronic materials will be the development of advanced characterization tools, particularly those targeted to measuring the charge‐transfer processes in heterogeneous, anisotropic, and hierarchically structured materials. This feature article describes the morphological properties that make partially ordered polymers an intriguing materials system to explore connections between chemical identity, solid‐phase microstructure, and hierarchical charge transport. To this end, recent directions in materials development and new opportunities for characterization are discussed.
Recent Advances in Cyclodextrin‐Based Light‐Responsive Supramolecular Systems
Authors: Zhang Xiaojin , Ma Xin , Wang Kang , Lin Shijun , Zhu Shitai , Dai Yu , Xia Fan 
Published: April 2018

AbstractCyclodextrins (CDs), one of the host molecules in supramolecular chemistry, can host guest molecules to form inclusion complexes via non‐covalent and reversible host‐guest interactions. CD‐based light‐responsive supramolecular systems are typically constructed using CDs and guest molecules with light‐responsive moieties, including azobenzene, arylazopyrazole, o‐nitrobenzyl ester, pyrenylmethyl ester, coumarin, and anthracene. To date, numerous efforts have been reported on the topic of CD‐based light‐responsive supramolecular systems, but these have not yet been highlighted in a separated review. This review summarizes the efforts reported over the past ten years. The main text of this review is divided into five sections (vesicles, micelles, gels, capturers, and nanovalves) according to the formation of self‐assemblies. This feature article aims to afford a comprehensive understanding of the light‐responsive moieties used in the construction of CD‐based light‐responsive supramolecular systems and to provide a helpful guide for the further design of CD‐based light‐responsive supramolecular systems.
Multiple Machine Learning Based‐Chemoinformatics Models for Identification of Histone Acetyl Transferase Inhibitors
Authors: Krishna Shagun , Kumar Sushil , Singh Deependra Kumar , Lakra Amar Deep , Banerjee Dibyendu , Siddiqi Mohammad Imran 
Published: April 2018

AbstractThe histone acetyl transferase (HAT) are involved in acetylation of histones that lead to transcription activation in numerous gene regulatory mechanisms. There are very few GCN5 HAT inhibitors reported despite of their role in cancer progression. In this study, we have utilized in‐silico virtual screening approaches based on various machine learning algorithm to identify potent inhibitors of GCN5 HAT from commercially available Maybridge library. We have generated predictive chemoinformatics models based on k‐Nearest neighbour, naïve Bayesian, Random Forest and Support Vector Machine. Based on statistical parameters, the RF and SVM models have shown comparative performance. Therefore, we performed the virtual screening with these two models and the consensus hits were selected for further evaluation using molecular docking into the active site of GCN‐5 HAT. Finally, a set of 10 molecules were selected and subjected to biological evaluation. Subsequently, inhibition of acetylation shown by three out of the ten molecules in the in‐vitro experiments validated their utility as potential HAT inhibitors. Furthermore, the selected hits have also shown weak cell growth decrease in MCF‐7 cancer cell lines, which suggests that after subsequent structural optimization the identified molecules may further be explored for the development of anti‐cancer agents.
Site‐Specific Surface Functionalization via Microchannel Cantilever Spotting (µCS): Comparison between Azide–Alkyne and Thiol–Alkyne Click Chemistry Reactions
Authors: Dadfar Seyed Mohammad Mahdi , Sekula‐Neuner Sylwia , Bog Uwe , Trouillet Vanessa , Hirtz Michael 
Published: April 2018

AbstractDifferent types of click chemistry reactions are proposed and used for the functionalization of surfaces and materials, and covalent attachment of organic molecules. In the present work, two different catalyst‐free click approaches, namely azide–alkyne and thiol–alkyne click chemistry are studied and compared for the immobilization of microarrays of azide or thiol inks on functionalized glass surfaces. For this purpose, the surface of glass is first functionalized with dibenzocyclooctyne‐acid (DBCO‐acid), a cyclooctyne with a carboxyl group. Then, the DBCO‐terminated surfaces are functionalized via microchannel cantilever spotting with different fluorescent and nonfluorescent azide and thiol inks. Although both routes work reliably for surface functionalization, the protein binding experiments reveal that using a thiol–alkyne route will obtain the highest surface density of molecular immobilization in such spotting approaches. The obtained achievements and results from this work can be used for design and manufacturing of microscale patterns suitable for biomedical and biological applications.
Co3O4 Nanosheets as Active Material for Hybrid Zn Batteries
Authors: Tan Peng , Chen Bin , Xu Haoran , Cai Weizi , He Wei , Liu Meilin , Shao Zongping , Ni Meng 
Published: April 2018

AbstractThe rapid development of electric vehicles and modern personal electronic devices is severely hindered by the limited energy and power density of the existing power sources. Here a novel hybrid Zn battery is reported which is composed of a nanostructured transition metal oxide‐based positive electrode (i.e., Co3O4 nanosheets grown on carbon cloth) and a Zn foil negative electrode in an aqueous alkaline electrolyte. The hybrid battery configuration successfully combines the unique advantages of a Zn–Co3O4 battery and a Zn–air battery, achieving a high voltage of 1.85 V in the Zn–Co3O4 battery region and a high capacity of 792 mAh gZn−1. In addition, the battery shows high stability while maintaining high energy efficiency (higher than 70%) for over 200 cycles and high rate capabilities. Furthermore, the high flexibility of the carbon cloth substrate allows the construction of a flexible battery with a gel electrolyte, demonstrating not only good rechargeability and stability, but also reasonable mechanical deformation without noticeable degradation in performance. This work also provides an inspiring example for further explorations of high‐performance hybrid and flexible battery systems.
Synergistic potential of fenvalerate and triadimefon on endocrine disruption and oxidative stress during rare minnow embryo development
Authors: Wu Shenggan , Hu Gaojie , Zhao Xueping , Wang Qiang , Jiang Jinhua 
Published: April 2018

AbstractPyrethroids have been reported to interact synergistically when co‐exposed with azoles fungicides in different organisms. In the present study, we investigated the mixture toxicity of fenvalerate (FEN) and triadimefon (TDF) toward embryos of Gobiocypris rarus after 96 h exposure. Results demonstrated that TDF enhanced the acute toxicity of FEN. Exposure to binary mixtures of FEN and TDF resulted in synergistic responses of endocrine disruption by inducing the transcripts of several genes including vtg, erα, erβ1, erβ2, cyp19a, cyp1a, cyp4, cyp11a, gnrh3, gnrhr1a, star, and dmrt1. Furthermore, FEN and TDF mixture increased the VTG level and aromatase activity in rare minnow embryos. FEN and TDF co‐exposure also regulated the mRNA of vezf, hsp70, p53, gadd45α, induced the synthesis of ROS and activity of GST, suggesting the synergistic potential of oxidative stress induced by FEN and TDF co‐exposure. The results indicated that binary mixtures of FEN and TDF could simultaneously induce endocrine disruption and oxidative stress in a synergistic manner during rare minnow embryo development.
EPA proposes TSCA user fees
Authors: Bergeson Lynn L. 
Published: April 2018

AbstractWe all knew it was coming, and the proposal has finally arrived. On February 8, 2018, the US Environmental Protection Agency (EPA) announced that EPA Administrator Scott Pruitt signed a proposed rule regarding user fees for the administration of the Toxic Substances Control Act (TSCA). As amended by the Frank Lautenberg Chemical Safety for the 21st Century Act, TSCA provides the EPA the authority to levy fees on certain chemical manufacturers, including importers and processors, to “provide a sustainable source of funding to defray resources that are available for implementation of new responsibilities under the amended law” (EPA, 2018a, p. 1). The EPA states in its press release that these fees:
would go toward developing risk evaluations for existing chemicals; collecting and reviewing toxicity and exposure data and other information; reviewing Confidential Business Information (CBI); and, making determinations in a timely and transparent manner with respect to the safety of new chemicals before they enter the marketplace. (EPA, , p. 1)This column summarizes the proposal and explains why it is significant.
A simple recipe for estimating atmospheric stability solely based on surface‐layer wind speed profile
Authors: Basu Sukanta 
Published: April 2018

AbstractThe wind energy community is gradually recognizing the significance of atmospheric stability in both power production and structural loading. However, estimating stability requires temperature gradient data which are not commonly measured by the wind farm developers or operators. To circumvent this problem, we propose a simple approach á la Swinbank, to estimate stability from only 3 levels of wind speed measurements. As such, this approach is ideally suited for sodar‐ and lidar‐based wind measurements owing to their high vertical resolution in the surface layer.
Genetic Counselors’ Experience with and Opinions on the Management of Newborn Screening Incidental Carrier Findings
Authors: Leppert Kristen , Bisordi Katharine , Nieto Jessica , Maloney Kristin , Guan Yue , Dixon Shannan , Egense Alena 
Published: April 2018

AbstractNewborn screening (NBS) is a public health program whose aim is to identify infants who will be clinically affected with a serious metabolic, genetic, or endocrine disorder; however, the technology utilized by many NBS programs also detects infants who are heterozygous carriers for autosomal recessive conditions. Discussion surrounding disclosure of these incidental carrier findings remains controversial. The purpose of this study was to assess genetic counselors’ attitudes about disclosure of carrier status results generated by NBS and to gather data on their experiences with incidental carrier findings. An electronic survey was distributed to genetic counselors of all specialties via the NSGC listserv, and a total of 235 survey responses were analyzed. Quantitative data were analyzed using IBM SPSS v24, and qualitative data were manually analyzed for thematic analysis. Results show that the counselor participants were overall in favor of routine disclosure. Those with experience in NBS were much more likely to strongly agree with one or more reasons for disclosure (p < 0.001), whereas those with five or fewer years of experience were more likely to strongly agree with one or more reasons for non‐disclosure (p = 0.031). Qualitative analysis identified key motivating factors for disclosure, including helping parents to understand a positive screen, parents may otherwise be unaware of reproductive risk and they may not otherwise have access to this information, and, while genetic testing is inherently a complex and ambiguous process, this does not justify non‐disclosure. The main motivating factor for non‐disclosure was the need for better counseling and informed consent. The data suggest that implementation of an “opt‐in/out” policy for parents to decide whether or not to receive incidental findings would be beneficial. The results of this study support the continued disclosure of incidental carrier findings; however, additional research is necessary to further determine and implement the most effective disclosure practices.
Visual evoked potentials are similar in polysomnographically defined quiet and active sleep in healthy newborns
Authors: Cubero‐Rego Lourdes , Corsi‐Cabrera María , Ricardo‐Garcell Josefina , Cruz‐Martínez Rogelio , Harmony Thalía 
Published: April 2018

AbstractMorphology and late components of evoked potentials change depending on wake‐sleep stages in adults. Visual Evoked potentials (VEPs) have been frequently studied in newborns to identify abnormal development of visual pathways; however, large variability has been reported and there is uncertainty as to the effect of sleep stages on VEPs in neonates.ObjectiveTo describe the characteristics of VEPs in one month old, healthy full‐term newborns during active sleep (AS) and quiet sleep (QS), defined by simultaneous polysomnography (PSG).MethodsVEPs were obtained by monocular LEDs stimulation of each eye during AS and QS, in 20 healthy full‐term newborns (gestational age 37–40 weeks) with normal birth weights and normal prenatal Doppler ultrasound indices. Latencies and amplitudes of N2, P2 and N3 components in AS and QS were compared, and their association with absolute power of EEG frequency bands, assessed.ResultsThere were no significant differences in VEP morphology, latencies and amplitudes between sleep states. Typical wave forms were obtained in all newborns in AS; however, no VEPs could be identified clearly in 3 newborns in QS; QS VEPs were less reliable than in AS: more averaging was required; correlation was significantly lower between the VEP averages; and a larger number of babies needed more than two averages to obtain replicable responses needed for clinical purposes.ConclusionsThese results indicate that changes in amplitude and latency of some VEP components observed in NREM and REM sleep in adults are not yet present in one month old newborns probably due to immaturity of cortical and sleep mechanisms. VEPs are more reliable during AS than QS in newborns. Systematic VEP recording during AS, and polysomnographic control to identify this stage, are highly recommended as methods that can increase there liability of neonatal VEPs.
Declining Sexual Activity and Desire in Men—Findings From Representative German Surveys, 2005 and 2016
Authors: Beutel Manfred E. , Burghardt Juliane , Tibubos Ana N. , Klein Eva M. , Schmutzer Gabriele , Brähler Elmar 
Published: April 2018

AbstractBackgroundSurveys have indicated an increase of sexual activity in aging men; recently, however, a decrease of sexual activity has been reported in young men.AimTo assess (i) sexual activity and desire and their determinants across the age range in a population-based male sample and (ii) their changes over 11 years.MethodsA representative survey of men (N = 1,095) 18 to 93 years old from 2016 was compared with a survey from 2005 (N = 1,106 men) with the same age range. Samples were drawn from the German population at random using standardized sampling procedures. Questions were filled out by participants in the presence of a trained interviewer. Sexual activity was compared using logistic regression with the factors survey (2005 vs 2016), living with a partner (yes vs no), and age. Frequency of sexual desire was compared using analysis of covariance with the factors survey (2005 vs 2016), living with a partner (yes vs no), and the covariate age.OutcomesSexual activity was assessed as having been intimate with someone in the past year; frequency of sexual desire was evaluated within the past 4 weeks.ResultsThe great majority of men cohabiting with a partner in 2016 was sexually active and indicated sexual desire until 70 years of age; half did so at an older age. Across the age range, men living without a partner reported considerably less sexual activity and desire. Compared with 2005, fewer men reported living with a partner. The overall proportion of men reporting sexual activity deceased from 81% to 73% in 2016 and absent sexual desire increased from 8% to 13%.Clinical TranslationThe findings highlight the relevance of living with a partner for sexual activity and desire. We advocate using a measure of sexual activity that encompasses many variants of intimate behavior.Strengths and LimitationsLarge and methodologically comparable population-based samples were compared. However, interpretations are limited by the absence of longitudinal data. We did not assess the effect of having a partner living elsewhere.ConclusionSexual activity and desire decreased, especially in the young and middle-age groups. The decrease of men living with a partner contributed to this decreased sexual activity and desire. There was a generation effect, with younger and middle-age men living without a partner becoming less sexually active and experiencing less desire compared with the previous survey. The findings unveil changes in sexual activity and desire in a short time span.
Underwater Photo-Elicitation: A New Experiential Marine Education Technique
Authors: Andrews Steve , Stocker Laura , Oechel Walter 
Published: April 2018

AbstractUnderwater photo-elicitation is a novel experiential marine education technique that combines direct experience in the marine environment with the use of digital underwater cameras. A program called Show Us Your Ocean! (SUYO!) was created, utilising a mixed methodology (qualitative and quantitative methods) to test the efficacy of this technique. Participants (adults and high school students) snorkelled, explored the ocean, and captured images both in and out of the water. Underwater photo-elicitation was proven effective at increasing awareness, eliciting emotional reactions, and fostering a sense of connection to the ocean. However, it was not necessarily effective for raising awareness of environmental issues nor for motivating pro-environmental behaviour. Interestingly, while some attitudes about and behaviours toward the ocean did become more environmentally sensitive, others appeared to shift unexpectedly away from environmental concern. This result was perhaps due to the lack in the program of an ecological knowledge-based component. Participants enjoying the beauty of the ocean did not realise the threats facing it or what to do about these. If the goal is to achieve significant attitude change and cultivate pro-environmental behaviour, this new approach should be supplemented with critical thinking/action competence and ecological/ocean literacy.
Can composite digital monitoring biomarkers come of age? A framework for utilization
Authors: Kovalchick Christopher , Sirkar Rhea , Regele Oliver B. , Kourtis Lampros C. , Schiller Marie , Wolpert Howard , Alden Rhett G. , Jones Graham B. , Wright Justin M. 
Published: April 2018

IntroductionThe application of digital monitoring biomarkers in health, wellness and disease management is reviewed. Harnessing the near limitless capacity of these approaches in the managed healthcare continuum will benefit from a systems-based architecture which presents data quality, quantity, and ease of capture within a decision-making dashboard.MethodsA framework was developed which stratifies key components and advances the concept of contextualized biomarkers. The framework codifies how direct, indirect, composite, and contextualized composite data can drive innovation for the application of digital biomarkers in healthcare.ResultsThe de novo framework implies consideration of physiological, behavioral, and environmental factors in the context of biomarker capture and analysis. Application in disease and wellness is highlighted, and incorporation in clinical feedback loops and closed-loop systems is illustrated.ConclusionsThe study of contextualized biomarkers has the potential to offer rich and insightful data for clinical decision making. Moreover, advancement of the field will benefit from innovation at the intersection of medicine, engineering, and science. Technological developments in this dynamic field will thus fuel its logical evolution guided by inputs from patients, physicians, healthcare providers, end-payors, actuarists, medical device manufacturers, and drug companies.
INEQUALITIES ASSOCIATED WITH RATIOS OF GAMMA FUNCTIONS
Authors: CRINGANU JENICA 
Published: April 2018

We use properties of the gamma function to estimate the products$\prod _{k=1}^{n}(4k-3)/4k$and$\prod _{k=1}^{n}(4k-1)/4k$, motivated by the work of Chen and Qi [‘Completely monotonic function associated with the gamma function and proof of Wallis’ inequality’,Tamkang J. Math.36(4) (2005), 303–307] and Morticiet al.[‘Completely monotonic functions and inequalities associated to some ratio of gamma function’,Appl. Math. Comput.240(2014), 168–174].
In vivoexperiences with magnetic resonance imaging scans in Vibrant Soundbridge type 503 implantees
Authors: Todt I , Mittmann P , Ernst A , Mutze S , Rademacher G 
Published: April 2018

AbstractObjective:To observe the effects of magnetic resonance imaging scans in Vibrant Soundbridge 503 implantees at 1.5Tin vivo.Methods:In a prospective case study of five Vibrant Soundbridge 503 implantees, 1.5T magnetic resonance imaging scans were performed with and without a headband. The degree of pain was evaluated using a visual analogue scale. Scan-related pure tone audiogram and audio processor fitting changes were assessed.Results:In all patients, magnetic resonance imaging scans were performed without any degree of pain or change in pure tone audiogram or audio processor fitting, even without a headband.Conclusion:In this series, 1.5T magnetic resonance imaging scans were performed with the Vibrant Soundbridge 503 without complications. Limitations persist in terms of magnetic artefacts.