bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fecal microbiota transplantation in recurrent Clostridium difficile infection: the first prospective study of 30 patients in Romania
Authors: Mihaela Laszlo , Pascu Oliviu , Leucuta Daniel-Corneliu , Andreica Vasile 
Published: May 2018

Abstract
Introduction: The infection with Clostridium difficile has increased in incidence worldwide and it raises many problems with regard to therapy, resistance to treatment and especially recurrence. Recurrence is frequent in patients treated for Clostridium difficile infection, requiring vancomycin by mouth, with limited alternatives. The literature shows that one of the most efficient treatment methods in Clostridium difficile infection is the transplantation of gut microbiota, also known as fecal microbiota transplantation. Aim: We present our results following FMT performed in patients with recurrent Clostridium difficile infection, and propose a simple and effective protocol for fecal microbiota transplantation. Study design: The study was prospective. The phases of the FMT procedure: assessment of patient eligibility, patient’s consent, identification and screening of donors, discontinuation of antibiotics (vancomycin, metronidazole) 3 days prior to the procedure. Methods: Between 2013 and 2015, FMT was performed in 30 patients with recurrent Clostridium difficile infection, by direct infusion of extensively processed donor fecal matter via colonoscopy. We followed up the patients for 12 months. Results: Immediate post-transplantation outcome in what concerns stool frequency during the follow-up period (7 days) was encouraging in 93.33% of patients. The donors were healthy individuals (53% 1st degree relatives), previously screened for possible infections and infestations. This result was sustained at 6-month and 12-month follow-up. Post-transplantation recurrence occurred in 6.67% (2 patients), which responded well to treatment and did not require a new vancomycin course. Conclusions: Fecal microbiota transplantation via colonoscopy is effective, safe, easy to perform, it yields lasting results and is therefore a good option for recurrent or treatment-resistant Clostridium difficile infection.
Phenotypic and molecular identification of carbapenemase-producing Enterobacteriaceae - challenges in diagnosis and treatment
Authors: Főldes Annamária , Bilca Doina-Veronica , Székely Edit 
Published: May 2018

Abstract
Introduction: Infections due to carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CPCRE) are an emerging global public health threat. The purpose of this study was to investigate phenotypic and genotypic features of CP-CRE strains isolated from hospitalized patients. Material and methods: Between 1st of January - 1st of July 2017, in the Department of Microbiology, “Dr. Constantin Opriş” County Emergency Hospital Baia Mare, Romania, 1110 strains of Enterobacteriaceae were isolated from bronchial secretions, urine, wounds and blood cultures. Bacterial identification and antimicrobial susceptibility tests were performed by conventional methods, Vitek 2 Compact and M.I.C.E. strips. We analysed all Enterobacteriaceae strains non-susceptible to carbapenems according to CLSI 2017 criteria. The modified Hodge test (MHT), the modified carbapenem inactivation method (mCIM) and the combination disks test (KPC, MBL, OXA-48 Confirm kit, Rosco Diagnostica) were used for phenotypic confirmation, whereas a multiplex PCR assay for genes blaKPC, blaNDM and blaOXA-48 was used for genetic confirmation. Results: 19 non-duplicate strains isolated from 16 patients were phenotypically identified as CP-CRE: Klebsiella pneumoniae (n=14), Escherichia coli (n=2), Providencia stuartii (n=2) and Serratia marcescens (n=1). Most strains were isolated from bronchial secretions (n=9). The carbapenem-hydrolizing enzymes were identified by the combination disks test as: KPC (n=9), OXA-48-like (n=5) and MBL (n=5). Molecular confirmation was performed in 18 phenotypically positive isolates with 100% concordant results with mCIM and combination disks test. Discrepant results were noticed with the MHT in case of 4 NDM-producers confirmed by PCR. All CP-CRE strains were resistant to all tested cephems. Three out of 9 K. pneumoniae strains tested against colistin were found resistant. Conclusions: The most common carbapenemase detected was KPC. Therapeutic options were limited in all positive cases. Rapid and reliable detection of CP-CRE is critical for preventing the spread of these pathogens
Natural Fibers and Biopolymers Characterization: A Future Potential Composite Material
Authors: Lalit Ranakoti , Mayank Pokhriyal , Ankur Kumar 
Published: May 2018

Abstract
Now days, green composite materials are now gaining popularity for the various industrial applications. It is a combination of naturally occurring reinforcement like jute, sisal, flax, hemp, and kenaf; and matrix materials like biopolymers or bio resins which have been derived from starch, and vegetable oils. It is becoming more desirable due to its properties like biodegradability, renewability and environment friendly. The present paper presents the various natural fibers and their combinations with biopolymers. The paper also reflects the key issue related to hydrophilic nature of natural fibers and their remedies for a good fiber and bio polymer adhesion. Furthermore the strategy used and major attributes of the green composite are also discussed.
Neural Networks - A Way to Increase the Fuel Efficiency of Vehicles
Authors: Milesich Tomáš , Danko Ján , Bucha Jozef 
Published: May 2018

Abstract
This paper deals with the possibility of creating a vehicle model using a hierarchy of neural networks. Based on this model, it is possible to build an optimization cycle that looks for parameters which are influencing the driving of vehicles along given path. The given path must include a driving through the town, out of town and along the highway section, so the test track contains the greatest number of driving modes. Data for neural network are obtained from the CAN bus and the GPS sensor. Based on the built model and given route it is looking for such route drive, where it eventually came that the development of fuel consumption is lower than in unoptimized drive.
Press-Fit Evaluation and Study of Displacement in Temperature Changes
Authors: Šlesar Peter , Jančo Roland 
Published: May 2018

Abstract
The article is devoted to bearing analysis, which has a specific shape. The outer ring is the body directly and the inner ring is the case. To determine optimal radial clearance or overlap are used the thermal / structural analysis. The article is logically divided into two parts. In the first analysis, was monitored the impact of the press-fit of the case into the body. In the second analysis, there are presented attained results in graphical outputs of displacements in the orbits at different operating temperatures. At the end of the article were evaluated and researched individual effects on bearing deformation.
PENGARUH GEOMETRI TERAS TERHADAP KINERJA NEUTRONIK PADA REAKTOR PEMBIAK CEPAT DENGAN SIKLUS BAHAN BAKAR TERTUTUP
Authors: Fitriyani Dian 
Published: May 2018

Telah dilakukan penelitian tentang pengaruh geometri teras terhadap kinerja neutronik padaÂ reaktor pembiak cepat dengan siklus bahan bakar tertutup. Penelitian dilakukan melalui simulasiÂ komputasi dengan memvariasikan geometri teras untuk reaktor pembiak cepat berpendingin logamÂ cair (Pb-Bi) dengan bahan bakar UN-PuN (Nitrida) yang beroperasi selama 20 tahun. Analisisdilakukan terhadap hasil pengamatan perubahan harga faktor multiplikasi neutron (keff), perubahanÂ nilai Burnup, perubahan nilai Breeding Ratio, dan perubahan densitas bahan fertil dan fisil diÂ dalam teras reaktor. Dari keseluruhan model teras reaktor yang diamati, model G5 (Z>>X)Â memberikan hasil yang terbaik dengan mempertahankan harga keff dalam batas toleransi reaktifitasÂ ($) Â± 0,05 selama 13 tahun. Nilai breeding ratio (BR) untuk seluruh model teras masih dalamÂ rentang yang diharapkan (BR>1), namun nilai BR paling baik diberikan oleh model teras G1Â (Z<<X). Nilai burnup untuk keseluruhan model meningkat seiring dengan banyaknya nuklidaÂ yang berfisi di dalam teras reaktor dan yang paling baik diberikan oleh model teras G1. BeberapaÂ nuklida baru hasil transmutasi bahan bakar muncul di dalam teras reaktor, contohnya 241Am.
Penentuan Koefisien Absorbsi dan Impedansi Material Akustik Resonator Panel Kayu Lapis (Plywood) Berlubang dengan Menggunakan Metode Tabung
Authors: Yuliantika Sonya , - Elvaswer 
Published: May 2018

Penelitian ini untuk menentukan nilai koefisien absorbsi bunyi dan impedansi akustik dengan menggunakan metode tabung impedansi.Â Sampel yang digunakan yaitu material beton dan kayu lapis.Â Rentang frekuensi yang digunakan yaitu 500 Hz, 1000 Hz, 2000 Hz, 4000 Hz dan 8000 Hz.Â Hasil menunjukkan bahwa koefisien absorbsi bunyi beton 0,25 pada frekuensi 2000 Hz. Setelah dilapisi resonator panel kayu lapis meningkat menjadi 0,51.Â Beton yang dilapisi resonator panel kayu lapis berlubang didapatkan koefisien absorbsi bunyi paling tinggi yaitu 0,61.Â Â Impedansi akustik paling tinggi pada beton dilapisi resonator panel kayu lapis berlubang yaitu sebesar 0,97-i0,05.
Analisis Burn Up pada Reaktor Cepat Berpendingin Gas Menggunakan Bahan Bakar Uranium Alam
Authors: Irka Feriska Handayani , Suâ€™ud Zaki 
Published: May 2018

Burn up analysis of gas cooled fast reactor (GCFR) with natural uranium fuel has been done. Burn up modification used in order to make reactor can be operated with natural uranium without enrichment. The reactor core subdivided into 10 regions with the same volume in radial directions. Optimization evaluated by burning natural uranium for 100 years and put each of its burn up result per year in reactor with certain configuration. After 10 years burn up period, fuel from first region was shuffling radially to second region and so on fuel from 9thÂ shuffling to 10th and then fuel from 10th was carried out from reactor core and fresh uranium input to the first region. Calculation has been done by using SRAC system code with JENDL-32 as library, with cylindrical two dimensional R-Z core models. Shuffling method was used in order to make reactor can be operated using natural uranium. . This natural uranium initially being burned by guessed power level of burn up. The height andÂ diameter core are 350 cm and 240 cm respectively. The volume fraction for this design is 65% fuel, 10% cladding and 25% coolant; with output power 700 MWTh.Â The result show that reactor demonstrated excellent performance with effective multiplication factor 1,055
Karakterisasi Sensor Gas Liquefied Petroleum Gas (LPG) Dari Bahan Semikonduktor Heterokontak CUO/CUO(TIO2)
Authors: Zelvia Essy Puspa , Elvaswer Elvaswer 
Published: May 2018

Telah dilakukan karakterisasi sensor Liquefied Petroleum Gas (LPG) berupa pelet heterokontak dengan lapisan pertama pelet adalah 100% mol CuO dan lapisan kedua pelet adalah CuO yang dicampur 10% mol, 20% mol, 30% mol, 40% mol dan 50% mol TiO2. Tahap pembuatan sensor LPG terdiri atas pencampuran bahan, kalsinasi pada temperatur 500oC selama 4 jam, penggerusan, kompaksi, dan sintering pada temperatur 700oC selama 4 jam.Â Sensor LPG diuji pada temperatur ruang (27oC) dengan melihat karakteristik arus dan tegangan (I-V), nilai sensitivitas, nilai konduktivitas dan karakterisasiÂ XRD. Karakteristik I-V menunjukkan perubahan terbesar terjadi pada sampel CuO/CuO(20% mol TiO2). Nilai sensitivitas tertinggi dimiliki sampel CuO/CuO(20% mol TiO2) sebesar 11,94 pada tegangan 10 volt, dan merupakan sampel yang paling bagus digunakan sebagai sensor gas LPG. Nilai konduktivitas tertinggi dimiliki sampel CuO/CuO(10% mol TiO2) dengan nilai konduktivitas di udara sebesar 6,60557x10-5 Î©-1m-1 dan nilai konduktivitas di LPG 25,80712x10-5 Î©-1m-1.Â Kata kunci : heterokontak, sensor LPG, CuO/CuO(TiO2), karakterisasi I-V, sensitivitas, konduktivitas.
The Potential Anti-Diabetic Effects of Some Plant Species
Authors: GÜVEN Celal , TAŞKİN Eylem , KAYA Salih Tunç , SEVGİLER Yusuf 
Published: May 2018

Diabetes mellitus is a global disease, of which prevalence increases rapidly. It causes severe
microvascular and macrovascular complications such as retinopathy, nephropathy,
cardiomyopathy, neuropathy etc. These contribute to morbidity and mortality in diabetic patients.
Therefore, it is important to find an effective therapy method(s) for the protection of body from
diabetes-related complications. In this sense, herbal products are of great importance. Herein, this
review will highlight the potential usage of some herbals as a preventive and/or therapeutic
approach in diabetes and discusses the possible underlying mechanisms of anti-diabetic actions.&nbsp;
MOBİL TELEFON VE GOOGLE HARİTA DESTEKLİ YEREL SEYAHAT ROTASI OPTİMİZASYONU: BURDUR ÖRNEĞİ
Authors: İLKUÇAR Muhammer , ÇETİNKAYA Ahmet 
Published: May 2018

Kişi
başına düşen gelir düzeyinin yükselmesi ve ulaşım imkanlarının kolaylaşmasıyla
birlikte iş veya turizm amaçlı seyahatler de artmıştır. Günümüzde turizm
faaliyetleri doğa, tarih, kültür, alışveriş gibi farklı alternatifler
sunmaktadır. Dolayısıyla insanlar kendi seyahat anlayışına göre farklı turizm
destinasyonlarını oluşturmak istemekte ve buna yardımcı olacak uygulamalara
ihtiyaç duymaktadırlar. Bu çalışmada akıllı cep telefonu yardımı ile kendi gezi
planımızı kolay bir şekilde oluşturma imkanı sunan, android tabanlı, mobil
uygulama geliştirilmiştir. Kullanıcı kendine uygun gezi noktalarını uygulama
marifetiyle Google harita üzerinden seçerek gezi turunu oluşturabilmektedir.
Uygulama, seçilen gezi noktaları arasındaki mesafeleri Google haritalar
üzerinden tespit edip, başlangıç ve bitiş konumlarına göre, genetik
optimizasyon algoritması kullanılarak en kısa turu hesaplayıp, turun rotasını
harita üzerinden görsel olarak sunmaktadır. En kısa tur hesaplama işlemi,
parametrik fonksiyon haline getirilerek, istendiğinde farklı rotalar için
dinamik olarak kullanılabilecektir.
Başlangıç ve bitiş noktaları belirtilmez ise sistem bulunduğu konumu
başlangıç ve bitiş konumları olarak otomatik tanımlayıp buna göre hesaplama
yapacaktır. Sistem, tüm hesaplamaları
kendi içinde yapacak ve bilgileri yine kendi üzerinde tutacağından, bu işlemler
için ayrıca bir sunucu bilgisayara ihtiyaç duymayacaktır. Hesaplamalarda Google
haritadan elde edilecek mesafeler kullanıldığından başka yol nitelikleri
(kavşak sayısı, sinyalizasyon, trafik yoğunluğu vb.) dikkate alınmamıştır. Uygulama, Burdur ilinde bazı seyahat
noktaları tespit edilip, buralarla ilgili bilgiler sisteme yüklenip test
edilmiştir.
BÖLGESEL GELİŞMEDE BİR ARAÇ OLARAK GİRİŞİMCİLİK: İL BAZINDA GİRİŞİMCİLİK EKOSİSTEMİNİN ÖLÇÜMÜ
Authors: OĞUZTİMUR SENAY , Seçkin Ebru 
Published: May 2018

1970’lerden
itibaren esnek uzmanlaşma, bilgi ve iletişim teknolojilerindeki gelişmeler;
yenilikçilik, KOBİ’lerin gücünü artırmasına imkân vermiştir. Diğer taraftan
bölgelerin yarışabilmesi için kendi içsel dinamiklerini ortaya çıkaracak
girişimlerde bulunmalar, girişimciliğin önemini artırarak, bölgesel gelişmede
belirleyici kavramlardan biri haline getirmiştir. Bölgelerarası dengesizliği
gidermek ve geri kalmış bölgelerin kendi içsel potansiyelleri doğrultusunda
bölgedeki girişimciliği canlandırmak bölgesel gelişme politikaları arasında yer
bulmaya başlamıştır. Bu kapsamda, literatür taraması yapılarak bölgesel gelişme
için girişimciliğin neden önemli olduğu ve girişimciliği etkileyen çevresel
unsurların neler olduğu ele alınmıştır. Girişimciliği etkilen dört temel unsur
belirlenmiştir: (I) Ekonomik faktörler, (II) İnsan sermayesi, (III) Fiziksel
altyapı, (IV) Yenilikçilik. Bu dört
temel unsurun açılımları normalleştirilerek dört ayrı endeks
oluşturulmuştur. Ardından il bazında bu
dört endeksin birlikte ele alındığı beşinci ve genel düzeyi gösteren endeks
hesaplanmıştır. Böylece, tüm Türkiye’deki illerin girişimcilik düzeyi açısından
değerlendirmesi yapılmıştır. Sonuçta;
gelişmişlik düzeyi yüksek olan illerin girişimcilik kapasitesinin de yüksek
olduğu tespit edilmiştir.
Estudio experimental de acopladores bicónicos de fibra óptica aplicados al desarrollo de multiplexores por división de longitud de onda
Authors: Hernández-Arriaga M.V. , Bello-Jiménez M. , Ibarra-Escamilla B. , Loredo-Trejo A. 
Published: May 2018

Se reporta un estudio experimental de la t\'ecnica de fabricaci\'on de acopladores bic\'onicos de fibra \'optica y su aplicaci\'on al desarrollo de multiplexores por divisi\'on de longitud de onda (WDM, wavelengthdivisionmultiplexer). Los par\'ametros de fabricaci\'on requeridos para el WDM son obtenidos del an\'alisis te\'orico de la respuesta espectral de un acoplador d\'ebilmente fusionado. Como caso particular, se reporta el desarrollo de un WDM 1550/1850 nm, el cual es un dispositivo fundamental en el desarrollo de l\'aseres de fibra \'optica dopada con Tulio. Las dimensiones finales del dispositivo son una longitud total de 36.3 mm, una cintura uniforme de 6.5 mm de largo con una secci\'on transversal de 23 μm. El dispositivo exhibe bajas p\'erdidas por inserci\'on de 0.17 dB, un espaciamiento entre canales de 303.52 nm y ancho de banda de ± 50 nm. Este trabajo establece una gu\'ia de fabricaci\'on para el desarrollo de acopladores y dispositivos WDM de fibra \'optica.
Light Curves of Lucy Targets: Leucus and Polymele
Authors: Buie Marc W. , Zangari Amanda M. , Marchi Simone , Levison Harold F. , Mottola Stefano 
Published: May 2018

Abstract
We present new observations from 2016 of two Jupiter Trojan asteroids that are targets for the Lucy Discovery mission. The extremely long rotation period of (11351) Leucus is confirmed and refined to a secure value of 445.732 ± 0.021 hr with photometric parameters of H

r
= 11.046 ± 0.003 and G

r
= 0.58 ± 0.02 in the SDSS r′ filter. This leads to a geometric albedo of p

V
= 4.7%. The amplitude of the light curve was measured to be 0.61 mag, unchanged from the value of one-fourth of a revolution earlier, suggesting a low obliquity. The first light-curve observations for (15094) Polymele are also presented. This object is revealed to have a much shorter rotation period of 5.8607 ± 0.0005 hr with a very low amplitude of 0.09 mag. Its photometric parameters are H

r
= 11.691 ± 0.002 and G

r
= 0.22 ± 0.02. These values lead to a refined geometric albedo of p

V
= 7.3%. This object is either nearly spherical or was being viewed nearly pole-on in 2016. Further observations are required to fully determine the spin pole orientation and convex-hull shapes.
ALMA Survey of Lupus Protoplanetary Disks. II. Gas Disk Radii
Authors: Ansdell M. , Williams J. P. , Trapman L. , Terwisga S. E. van , Facchini S. , Manara C. F. , Marel N. van der , Miotello A. , Tazzari M. , Hogerheijde M. , Guidi G. , Testi L. , Dishoeck E. F. van 
Published: May 2018

Abstract
We present Atacama Large Millimeter/Sub-Millimeter Array (ALMA) Band 6 observations of a complete sample of protoplanetary disks in the young (∼1–3 Myr) Lupus star-forming region, covering the 1.33 mm continuum and the 12CO, 13CO, and C18O J = 2–1 lines. The spatial resolution is ∼0.″25 with a medium 3σ continuum sensitivity of 0.30 mJy, corresponding to M
dust ∼ 0.2 M
⊕. We apply Keplerian masking to enhance the signal-to-noise ratios of our 12CO zero-moment maps, enabling measurements of gas disk radii for 22 Lupus disks; we find that gas disks are universally larger than millimeter dust disks by a factor of two on average, likely due to a combination of the optically thick gas emission and the growth and inward drift of the dust. Using the gas disk radii, we calculate the dimensionless viscosity parameter, α
visc, finding a broad distribution and no correlations with other disk or stellar parameters, suggesting that viscous processes have not yet established quasi-steady states in Lupus disks. By combining our 1.33 mm continuum fluxes with our previous 890 μm continuum observations, we also calculate the millimeter spectral index, α
mm, for 70 Lupus disks; we find an anticorrelation between α
mm and millimeter flux for low-mass disks (M
dust ≲ 5), followed by a flattening as disks approach α
mm ≈ 2, which could indicate faster grain growth in higher-mass disks, but may also reflect their larger optically thick components. In sum, this work demonstrates the continuous stream of new insights into disk evolution and planet formation that can be gleaned from unbiased ALMA disk surveys.
Spectral Study of A1Π–X1Σ+ Transitions of CO Relevant to Interstellar Clouds
Authors: Cheng Junxia , Zhang Hong , Cheng Xinlu 
Published: May 2018

Abstract
Highly correlated ab initio calculations were performed for an accurate determination of the A
1Π–X
1Σ+ system of the CO molecule. A highly accurate multi-reference configuration interaction approach was used to investigate the potential energy curves (PECs) and the transition dipole moment curve (TDMC). The resultant PECs and TDMC found by using the aug-cc-pV5Z (aV5Z) basis set and 5330 active spaces are in good agreement with the experimental data. Moreover, the Einstein A coefficients, lifetimes, ro-vibrational intensities, absorption oscillator strengths, and integrated cross sections are calculated so that the vibrational bands include v″ = 0–39

v′ = 0–23. For applications in the atmosphere and interstellar clouds, we studied the transition lineshapes to Gaussian and Lorentzian profiles at different temperatures and pressures. The intensities were calculated at high temperature that was used to satisfy some astrophysical applications, such as in planetary atmospheres. The results are potentially useful for important SAO/NASA Astrophysics Data System and databases such as HITRAN, HITEMP, and the National Institute of Standards and Technology. Because the results from many laboratory techniques and our calculations now agree, analyses of interstellar CO based on absorption from A
1Π–X
1Σ+ are no longer hindered by present spectral parameters.
The Parallax of the Red Hypergiant VX Sgr with Accurate Tropospheric Delay Calibration
Authors: Xu 徐双 Shuangjing 敬 , Zhang 张 Bo 波 , Reid Mark J. , Menten Karl M. , Zheng 郑兴 Xingwu 武 , Wang 王广 Guangli 利 
Published: May 2018

Abstract
We report astrometric results of VLBI phase-referencing observations of 22 GHz H2O masers emission toward the red hypergiant VX Sgr, one of most massive and luminous red hypergiant stars in our Galaxy, using the Very Long Baseline Array. A background source, J1820−2528, projected 4.°4 from the target VX Sgr, was used as the phase reference. For the low decl. of these sources, such a large separation normally would seriously degrade the relative astrometry. We use a two-step method of tropospheric delay calibration, which combines the VLBI geodetic-block (or Global Positioning System) calibration with an image-optimization calibration, to obtain a trigonometric parallax of 0.64 ± 0.04 mas, corresponding to a distance of

kpc. The measured proper motion of VX Sgr is 0.36 ± 0.76 and −2.92 ± 0.78 mas yr−1 in the eastward and northward directions. The parallax and proper motion confirms that VX Sgr belong to the Sgr OB1 association. Rescaling bolometric luminosities in the literature to our parallax distance, we find that the luminosity of VX Sgr is (1.95 ± 0.62) × 105
L
⊙, where the uncertainty is dominated by differing photometry measurements.