bluuebunny/crossref_metadata_2025_split huggingface dataset:
Close female friendships and knowledge of recommended abortion methods in Nigeria and the Democratic Republic of the Congo among a representative sample of reproductive-aged women
Authors: Anjur-Dietrich Selena P. , Rhoades Alice , Akilimali Pierre Z. , OlaOlorun Funmilola M. , Omoluabi Elizabeth , Bell Suzanne O. 
Published: October 2024

IntroductionThere is a high incidence of unsafe abortion among women in Nigeria and the DRC. Low knowledge of recommended abortion methods [i.e., surgical and medication abortion (MA) pills] is a barrier for women accessing safe abortions. Women often rely on friends for information about abortion methods. Understanding characteristics of women with knowledge of recommended abortion methods, and MA specifically, and how it is influenced by close female friendships may help identify women most at risk of relying on unsafe abortion.MethodsWe used survey data from Performance Monitoring for Action from 11,106 women of reproductive age in Nigeria (April–May 2018) and 3,697 women in Kinshasa and Kongo Central, DRC, (December 2021–April 2022) to produce representative estimates of knowledge of abortion methods at the national and province levels, respectively. We performed bivariate and multivariate logistic regression to determine which characteristics were independently associated with knowing a recommended abortion method, with knowing of MA pills specifically, and to assess our hypothesis that having at least one female confidante would increase one's odds of knowing about these methods.ResultsA minority (26.9%) of women in Nigeria and the majority in Kinshasa (76.7%) and Kongo Central (58.1%) reported having knowledge of at least one recommended abortion method, while knowledge of MA pills was low in all sites. Having at least one close female confidante was associated with increased odds of knowing a recommend abortion method in Nigeria (aOR = 1.50, 95% CI 1.25–1.79) and in Kongo Central (aOR = 2.66, 95% CI 1.40–5.40), and with increased odds of knowing about MA specifically in Kinshasa (aOR = 1.44, 95% CI 1.08–1.93) and Kongo Central (aOR = 3.61, 95% CI 1.28–10.22), but not Nigeria.DiscussionIn legally restrictive contexts where knowledge of recommended abortion methods (particularly medication abortion) is low, having close female friends is related to increased knowledge of recommended abortion methods.
Kinematic analysis of the back squat at different load intensities in powerlifters and weightlifters
Authors: Giustino Valerio , Vicari Domenico Savio Salvatore , Figlioli Flavia , Gervasi Marco , Fernández Peña Eneko , Schifaudo Naima , Tedesco Mattia , Drid Patrik , Paoli Antonio , Battaglia Giuseppe , Bianco Antonino , Patti Antonino 
Published: October 2024

IntroductionThis study aimed to evaluate the angular kinematics of the hip, knee, ankle, and the linear kinematics of the barbell during the back squat (BS) at different load intensities in powerlifters and weightlifters.MethodsSeventeen athletes were recruited (n = 14 powerlifters; n = 3 weightlifters). The 1-RM of the BS of each participant was calculated and, 1-week after, each participant was asked to perform 5 trials of the BS at different load intensities (i.e., 60%, 70%, 80%, 90%, 100%) of the 1-RM. An action camera recorded the execution of each BS trial in the sagittal plane and, afterward, the videos were analyzed by measuring the range of motion (ROM) of hip, knee, and ankle for the angular kinematics, and the timing, distances, speeds, and accelerations of the barbell for the linear kinematics.ResultsRegarding the angular kinematics, no significant differences were found in the parameters in the starting and ending positions among the 5 trials, while a significant decrease was found in the hip relative angle (p = 0.026) in the maximum flexion position as load intensity increased. Regarding the linear kinematics, a significant difference was found in the descent acceleration (p = 0.049) in the descent phase, while a significant difference was found in the ascent speed (p &lt; .001) and vertical speed of ascent (p &lt; .001) in the ascent phase, which decreased as load intensity increased.DiscussionOur findings show that the angular and linear kinematics of BS change as load intensity increases.
The prevalence of non-sentinel lymph node metastasis among breast cancer patients with sentinel lymph node involvement and its impact on clinical decision-making: a single-centred retrospective study
Authors: Ding Jingxian , Jiang Xiaoliu , Huang Zhaohui , Ji Qiao , Long Jie , Cao Yali , Guo Yonghong 
Published: October 2024

BackgroundSentinel lymph node biopsy (SLNB) has become standard procedure for early breast cancer patients with clinically node negative disease. The patients with SLN metastasis normally underwent axillary lymph node dissection (ALND). However, the metastatic status of non-sentinel Lymph nodes (non-SLNs) varied significantly in different reports. Here, we evaluated the prevalence of non-SLNs metastasis among breast cancer patients with sentinel lymph node metastasis and its impact on clinical decision-making.Materials and MethodsWe identified 892 female patients with operable cT1-3N0 invasive breast cancer who underwent ALND in our center due to SLN metastasis from 2017 to 2023, retrospectively. The prevalence of non-SLN metastasis among different clinicopathological traits and its correlation with the number of positive SLNs were analyzed. The optimal clinical decision-making was generalized.ResultsThe median number of SLN+, SLN, non-SLN+ and non-SLN was 2, 4, 1 and 14 among the enrolled 892 female patients, respectively. 504 (56.50%) patients with SLN + had at least one metastatic lymph node in the harvested non-SLNs. Among the enrolled 892 female patients, 435 (48.77%) patients with 1 positive SLN, of which 180 (41.38%) had at least one additional metastatic non-SLNs. 242 (27.13%) patients with 2 positive SLNs, of which 146 (60.33%) had at least one metastatic non-SLNs. For the rest 215 (24.10%) patients with at least 3 metastatic SLNs, 178 (82.79%) had at least one metastatic non-SLNs. In the univariate analysis, the non-SLNs metastatic status was correlated with the number of SLNs+, tumor size, tumor grade, lymphovascular invasion (LVI) and molecular subtypes, but not histopathologic type. In the multivariate analysis, the risk of additional non-SLNs metastasis correlated with the number of SLNs+, SLNs, non-SLNs and LVI.ConclusionOmiting ALND in patients with higher non-SLNs + rate outside the American College of Surgeons Oncology Group (ACSOG) Z0011 and the European Organization for Research and Treatment of Cancer (EORTC) 10,981–22023 AMAROS criteria should be considered with caution in clinical decision-making. To evaluate whether axillary radiotherapy and ALND provides equivalent regional control in breast cancer patients with obvious residual metastatic lymph nodes undesected in the axilla, a well-matched prospective randomized controlled trial is an urgent need.
Activation of the Innate Immune System in Brain-Dead Donors Can Be Reduced by Luminal Intestinal Preservation During Organ Procurement Surgery - A Porcine Model
Authors: Weiss Marc Gjern , de Jong Anne Marye , Seegert Helene , Moeslund Niels , Maassen Hanno , Schjalm Camilla , de Boer Eline , Leuvenink Henri , Mollnes Tom Eirik , Eijken Marco , Keller Anna Krarup , Dijkstra Gerard , Jespersen Bente , Pischke Søren Erik 
Published: October 2024

Organs obtained from brain dead donors can have suboptimal outcomes. Activation of the innate immune system and translocation of intestinal bacteria could be causative. Thirty two pigs were assigned to control, brain death (BD), BD + luminal intestinal polyethylene glycol (PEG), and BD + luminal intestinal University of Wisconsin solution (UW) groups. Animals were observed for 360 min after BD before organ retrieval. 2,000 mL luminal intestinal preservation solution was instilled into the duodenum at the start of organ procurement. Repeated measurements of plasma C3a, Terminal Complement Complex (TCC), IL-8, TNF, and lipopolysaccharide binding protein were analysed by immunoassays. C3a was significantly higher in the BD groups compared to controls at 480 min after brain death. TCC was significantly higher in BD and BD + UW, but not BD + PEG, compared to controls at 480 min. TNF was significantly higher in the BD group compared to all other groups at 480 min. LPS binding protein increased following BD in all groups except BD + PEG, which at 480 min was significantly lower compared with all other groups. Brain death induced innate immune system activation was decreased by luminal preservation using PEG during organ procurement, possibly due to reduced bacterial translocation.
К ВОПРОСУ О НЕОБХОДИМОСТИ ПОВЫШЕНИЯ КАЧЕСТВА КАЗАХСТАНСКИХ НАУЧНЫХ ПУБЛИКАЦИЙ ДЛЯ УСПЕШНОЙ ИНТЕГРАЦИИ В МЕЖДУНАРОДНОЕ НАУЧНОЕ СООБЩЕСТВО
Authors: Т.К. Рахыпбеков , А.М. Гржибовский 
Published: October 2024

Данной статьей мы открываем серию публикаций об основных принципах планирования исследований в здравоохранении и статистической обработки биомедицинских данных. Настоящая статья представляет собой несистематический обзор литературы, направленный на изучение качества научных публикаций в Республике Казахстан и в других странах, подтверждая необходимость повышения качества казахстанских научных публикаций для успешной интеграции в международное научное сообщество. Серия публикаций на 2015 год включает статьи об основных принципах планирования исследований, расчета необходимого размера выборки и методах статистического анализа данных для поперечных, когортных, экологических и экспериментальных исследований, а также исследований типа «случай-контроль».
This is an introductory article which opens a series of publications about basic principles of research design in health sciences and statistical analysis of biomedical data. In this paper we present a non-systematic review of literature assessing scientific quality of publications in Kazakhstan and other countries justifying the need for improvement of quality of Kazakhstani research papers, which is a pre-requisite of successful integration in the international biomedical research community. The series will cover cross-sectional, cohort, cross-sectional, ecological and experimental studies, but does not substitute specialized literature in clinical epidemiology.
Осы мақаламен біз денсаулық сақтаудағы зерттеулерді жоспарлаудың негізгі принциптері және биомедициналық мәліметтердің статистикалық өңделуі туралы жарияланымдар топтамасын ашамыз. Осы мақала Халықаралық ғылыми қоғамдастықтатабысты интеграция үшін қазақстандық ғылыми жарияланымдардың сапасын арттыру қажеттілігін растай отырып, Қазақстан Республикасында және басқа мемлекеттерде ғылыми жарияланымдар сапасын зерделеуге бағытталған жүйелі емес әдебиетті шолудан тұрады. 2015 жылға жарияланымдар топтамасы зерттеулерді жоспарлаудың негізгі принциптері, көлденең, когортты, экологиялық және сараптамалық зерттеулер үшін қажетті таңдау көлемін есептеу және мәліметтердің статистикалық талдау әдістері туралы мақалалардан, сол сияқты«бақылау - жағдай» сынды зерттеулерден тұрады.
ҚАЗІРГІ УАҚЫТТАҒЫ МЕКТЕП ОҚУШЫЛАРЫНЫҢ ДЕНСАУЛЫҚ ЖАҒДАЙЫ
Authors: Г.К. Амантаева , А.Б. Досымханова , М.Б. Бейсенгазина , Н.Ж. Чайжунусова 
Published: October 2024

Бұл мақалада оқушылардың денсаулық жағдайы динамикасының жағымсыз тенденциясы және өскелең ұрпақ денсаулығын сақтау және қалыптастырудағы білім беру жүйесінің рөлі жөніндегі мәліметтерге талдау жасалған.
This article contains an analysis of the role of the negative tendencies in the dynamics of the pupils’ health status and the school education system in creating and maintaining the health of the younger generation.
В данной статье отражен анализ роли негативных тенденций динамики состояния здоровья школьников и системы образования в формировании и сохранении здоровья подрастающего поколения.
СИМУЛЯЦИОННЫЙ ТРЕНИНГ ДЛЯ ИНТЕРНОВ-ВРАЧЕЙ ОБЩЕЙ ПРАКТИКИ 6 КУРСА
Authors: Д.А. Муканова , Ж.И. Смагулова , А.Т. Рыспаева 
Published: October 2024

Одним из главных направлений в сфере высшего медицинского образования является усиление практической части подготовки будущих врачей при сохранении должного уровня теоретических знаний. Современный уровень развития технологий симуляционного обучения позволяют реализовать новый метод практической подготовки и объективной оценки уровня практических знаний и умений – симуляционный тренинг – реалистичное моделирование сценариев патологических состояний, медицинских манипуляций, неотложных вмешательств и иных клинических ситуаций. Цель: ознакомить читателей со значительным преимуществом симуляционного тренинга для интернов-врачей общей практики 6 курса, в сравнении с традиционной системой подготовки, имеющейся возможностью многократной отработки действий, доведения их до автоматизма, а также объективного контроля качества оказания медицинской помощи по результатам выполнения тренинга. [3]
One of the main directions in the field of higher medical education is to strengthen the practical part of training future doctors while maintaining the proper level of theoretical knowledge. The modern level of development of technologies for simulation training makes it possible to implement a new method of practical training and an objective assessment of the level of practical knowledge and skills - simulation training - realistic modeling of scenarios of pathological conditions, medical manipulations, urgent interventions and other clinical situations. Purpose: to familiarize readers with the significant advantage of simulation training for 6th-year general practitioners in comparison with the traditional teaching system, with the available opportunity of repeated practicing of practical skills, bringing them to automatism, also objective quality control of medical care based on the training results. [3]
Жоғары медициналық білім беру саласындағы басты бағыттардың бірі - теориялық білімнің тиісті деңгейін сақтай отырып болашақ дәрігерлерді даярлаудың тәжірибелік бөлігін күшейту. Симуляциялық оқыту технологияларын дамытудың заманауи деңгейі тәжірибелік сабақтардың жаңа әдісін және тәжірибеоік білім мен дағдылар деңгейін объективті бағалауды - симуляциялық оқыту - патологиялық жағдайлардың сценарийлерін, медициналық манипуляцияларды, жедел араласуды және басқа клиникалық жағдайларды шынайы модельдеуді жүзеге асыруға мүмкіндік береді. Мақсаты: 6-курстың жалпы практика дәрігерлеріне симуляциялық оқытудың маңызды артықшылығымен таныстыру, дәстүрлі оқыту жүйесімен салыстырғанда, әрекеттерді қайталап тәжірибеде қолдану мүмкіндігі, оларды автоматизмге келтіру, сонымен қатар оқыту нәтижелері бойынша медициналық көмек сапасын объективті бақылау. [3]
ПЕРВЫЙ ОПЫТ ПРЕПОДАВАНИЯ ПЕДИАТРИИ ОНЛАЙН В УСЛОВИЯХ ПАНДЕМИИ
Authors: Д.А. Ахметжанова , Ю.Ф. Лобанов , Б.Б. Дюсупова , Л.А. Строзенко , И.Ю. Болденкова , В.Э. Миллер , М.В. Оробей 
Published: October 2024

Дистанционное обучение в медицине в качестве основного метода до настоящего времени применялось только в сфере последипломного образования. Развитие пандемии COVID-19 потребовало использования беспрецедентных мер безопасности, в том числе в области образования. Цель работы: Оценка положительных и отрицательных факторов использования методик дистанционного обучения педиатров на примере Алтайского государственного медицинского университета и Медицинского университета Семей. Проведен анализ методологии и первых результатов дистанционного обучения образовательного процесса на кафедрах педиатрического профиля. Использованы различные образовательные платформы (Moodle и KEYPS). В результате определены сходные показатели удовлетворенности студентов процессом и практические идентичные проблемы обоих вузов, связанные с определенной недостаточностью технологической базы и подготовки профессорско-преподавательского состава к работе в новых условиях.
Distance learning in medicine as the main method until now has only been used in postgraduate education. The development of the COVID-19 pandemic required the use of unprecedented security measures, including in the field of education. Purpose of the work: Assessment of positive and negative factors in the use of distance learning methods for pediatricians on the example of Al-Thai State Medical University and Semey Medical University. The analysis of the methodology and the first results of distance learning of the educational process at the departments of the pediatric profile. Various educational platforms are used (Moodle and KEYPS). As a result, we have identified similar indicators of student satisfaction with the process and practically identical problems of both universities, associated with a certain lack of technological base and training of the teaching staff to work in new conditions.
Қашықтықтан оқыту медицинадағы негізгі әдіс ретінде осы уақытқа дейін тек жоғары оқу орнынан кейінгі білім беруде қолданылып келді. COVID-19 пандемиясының дамуы бұрын-соңды болмаған қауіпсіздік шараларын, соның ішінде білім беру саласында қолдануды талап етті. Жұмыстың мақсаты: Алтай мемлекеттік медициналық университеті мен Семей медициналық университеті мысалында педиатрларға қашықтықтан оқыту әдістерін қолданудағы жағымды және жағымсыз факторларды бағалау. Педиатрлық бейін кафедраларында оқу процесін қашықтықтан оқытудың әдістемесі мен алғашқы нәтижелерін талдау. Әр түрлі білім беру платформалары қолданылады (Moodle және KEYPS). Нәтижесінде біз студенттердің белгілі бір технологиялық базаның жетіспеушілігімен және оқытушылар құрамының жаңа жағдайда жұмыс істеуге даярлануымен байланысты екі университеттің үдерісіне және іс жүзінде бірдей мәселелеріне қанағаттанудың ұқсас көрсеткіштерін анықтадық.
КЛЕТОЧНЫЕ МЕХАНИЗМЫ ПАМЯТИ. ТЕОРИЯ ИЕРАРХИЧЕСКОЙ СИСТЕМЫ ОСЦИЛЛЯТОРОВ, ЯВЛЯЮЩИХСЯ РЕЦИПРОКНЫМИ ПОЛОЖИТЕЛЬНЫМИ ОБРАТНЫМИ СВЯЗЯМИ ИЛИ ТЕОРИЯ ЯЗЫКА
Authors: В.А. Сычев 
Published: October 2024

Данная теория является развитием Общей когнитивной теории. Общая когнитивная теория описывает принципы построения психики и взаимодействия людей в результате которого возникает культура. Теория говорит о том, что наша психика представляет собой иерархическую систему взаимно возбуждаемых групп (популяций) нейронов, сохраняющих последовательности сигналов рецепторов, совпадающих по времени с возбуждением популяций клеток, отвечающих за инстинкты (эмоции). Но в Общей когнитивной теории не описывается, каким именно образом сохраняются последовательности афферентных сигналов от рецепторов, последовательности таких последовательностей и следующие уровни иерархии. Данная статья, посвящена конкретным механизмам сохранения таких последовательностей.
This theory is a development of the General Cognitive Theory. General cognitive theory describes the principles of building the psyche and the interaction of people as a result of which culture arises. The theory suggests that our psyche is a hierarchical system of mutually excited groups (populations) of neurons that store sequences of receptor signals that coincide in time with the excitation of cell populations responsible for instincts (emotions). But the General Cognitive Theory does not describe exactly how the sequences of afferent signals from receptors, the sequences of such sequences, and the next levels of the hierarchy are stored. This article is devoted to specific mechanisms for saving such sequences.
ИЗМЕНЕНИЕ ЛАТЕРАЛЬНЫХ ПРЕДПОЧТЕНИЙ В ВЕСТИБУЛЯРНОЙ И СЛУХОВОЙ СИСТЕМЕ В ОНТОГЕНЕЗЕ
Authors: В.Л. Ефимова , Е.И. Николаева , Е.Г. Вергунов , Л.Г. Буйнов 
Published: October 2024

Поставлен вопрос относительно предпочтения левой или правой сторон в вестибулярной системе. Важным отличием вестибулярной системы от других систем является то, что она не имеет первичной локализации в коре головного мозга. Цель исследования: изучить специфику латеральных предпочтений в вестибулярной и слуховой системе в онтогенезе. Было обследовано 383 ребёнка (290 мальчиков, 93 девочки) в возрасте от 1,1 до 13,7 года (средний возраст 5,5±2,4 года; формат M±SD). Все дети посещали дошкольные учреждения общеразвивающего вида или общеобразовательные школы. Для проведения исследования были получены разрешения родителей. В процессе исследования был использован следующий набор методик: регистрация акустических стволовых вызванных потенциалов с использованием метода VI пика; оценка функции полукружных каналов вестибулярного аппарата путём регистрации длительности поствращательного нистагма, оценка отолитовой функции вестибулярного аппарата проводилась методом цервикальных вестибулярных миогенных вызванных потенциалов. Для оценки изменений выраженности асимметрии в онтогенезе был применён многомерный анализ. Данные свидетельствуют о том, что асимметрия в слуховой сфере закладывается при рождении, тогда как асимметричные изменения нистагма и вестибулярной функции постепенно усиливаются и связаны с постепенным преобладанием правого полушария в переработке информации.
The question was raised regarding the preference of the left or right sides in the vestibular system. An important difference between the vestibular system and other systems is that it does not have a primary localization in the cerebral cortex. The purpose of the study: to study the specifics of lateral preferences in the vestibular and auditory systems in ontogeny. We examined 383 children (290 boys, 93 girls) aged 1.1 to 13.7 years (mean age 5.5±2.4 years; M±SD format). All children attended preschool institutions of a general developmental type or general education schools. Parental permission was obtained for the study. During the study, the following set of techniques was used: registration of acoustic stem evoked potentials using the VI peak method; assessment of the function of the semicircular canals of the vestibular apparatus by recording the duration of postrotational nystagmus, assessment of the otolithic function of the vestibular apparatus was carried out by the method of cervical vestibular myogenic evoked potentials. To assess changes in the severity of asymmetry in ontogeny, a multivariate analysis was used. The data suggest that asymmetry in the auditory sphere is established at birth, while asymmetric changes in nystagmus and vestibular function gradually increase and are associated with the gradual predominance of the right hemisphere in information processing.
СТАБИЛОМЕТРИЯ В ОЦЕНКЕ ДИСПРАКСИИ У ДЕТЕЙ С РЕЧЕВЫМИ НАРУШЕНИЯМИ
Authors: О.М. Силантьева , О.В. Баландина , У.А. Насонова , А.В. Коткова 
Published: October 2024

В статье приведён обзор диагностических методик с использованием стабилометрических критериев у детей с нарушениями двигательных функций, которые обусловлены отставанием созревания структур головного мозга, ответственных за реализацию процессов управления построением движений, что приводит к нарушению тонкой моторики и поддержания статического и динамического баланса тела. Стабилометрия является методом функциональной диагностики опорно-двигательной системы и может быть использована в качестве объективного метода оценки развития детей младшего школьного возраста. Стабилометрическое тестирование подтвердило актуальность использования данного метода для диагностики диспраксии, а также выявления дефицита когнитивных функций.
The article provides a review of diagnostic techniques using stabilometry criteria in children with impaired motor functions, which are caused by delayed maturation of the brain structures responsible for the realization of control processes of movement construction, which leads to impairment of fine motor skills and maintenance of static and dynamic body balance. Stabilometry is a method of functional diagnostics of the musculoskeletal system and can be used as an objective method for assessing the development of children of primary school age. Stabilometry testing confirmed the relevance of using this method for diagnosing dyspraxia as well as detecting cognitive deficits.