bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of intrafractional spinal cord and spinal canal movement during stereotactic MR-guided online adaptive radiotherapy for kidney cancer
Authors: Yamamoto Takaya , Tanaka Shohei , Takahashi Noriyoshi , Umezawa Rei , Suzuki Yu , Kishida Keita , Omata So , Takeda Kazuya , Harada Hinako , Sato Kiyokazu , Katsuta Yoshiyuki , Kadoya Noriyuki , Jingu Keiichi 
Published: October 2024

Background and purpose
This study aimed to investigate the intrafractional movement of the spinal cord and spinal canal during MR-guided online adaptive radiotherapy (MRgART) for kidney cancer.

Materials and methods
All patients who received stereotactic MRgART for kidney cancer between February 2022 and February 2024 were included in this study. Patients received 30–42 Gy in 3-fraction MRgART for kidney cancer using the Elekta Unity, which is equipped with a linear accelerator and a 1.5 Tesla MRI. MRI scans were performed at three points during each fraction: for online planning, position verification, and posttreatment assessment. The spinal cord was contoured from the upper edge of Th12 to the medullary cone, and the spinal canal was contoured from Th12 to L3, using the first MRI. These contours were adjusted to the second and third MR images via deformable image registration, and movements were measured. Margins were determined via the formula “1.3×Σ+0.5×σ” and 95% prediction intervals.

Results
A total of 22 patients (66 fractions) were analyzed. The median interval between the first and third MRI scans were 38 minutes. The mean ± standard deviation of the spinal cord movements after this interval were −0.01 ± 0.06 for the x-axis (right–left), 0.01 ± 0.14 for the y-axis (caudal–cranial), 0.07 ± 0.05 for the z-axis (posterior–anterior), and 0.15 ± 0.08 for the 3D distance, respectively. The correlation coefficients of the 3D distance between the spinal cord and the spinal canal was high (0.92). The calculated planning organ at risk volume margin for all directions was 0.11 cm for spinal cord. The 95% prediction intervals for the x-axis, y-axis, and z-axis were −0.11–0.09 cm, −0.23–0.25 cm and −0.14–0.03 cm, respectively.

Conclusions
Margins are necessary in MRgART to compensate for intrafractional movement and ensure safe treatment delivery.
Kurdistan + 100: Stories from a Future State, Orsola Casagrande and Mustafa Gundogdu (eds) (2023)
Authors: Havolli Din 
Published: October 2024

Review of: Kurdistan + 100: Stories from a Future State, Orsola Casagrande and Mustafa Gundogdu (eds) (2023)
Manchester: Comma Press, 236 pp.,
ISBN 978-1-91269-736-6, p/bk, £10.99
Seriously Mad: Mental Distress and the Broadway Musical, Aleksei Grinenko (2024)
Authors: Barr Lindsey R. 
Published: October 2024

Review of: Seriously Mad: Mental Distress and the Broadway Musical, Aleksei Grinenko (2024)
Ann Arbor: University of Michigan Press, 271 pp.,
ISBN 978-0-47205-644-6, p/bk, $39.95
Influence of cam profile errors in a modulator on the dynamic response of the heald frame
Authors: Yin Honghuan , Yu Hongbin , Zhang Weiye 
Published: October 2024

Abstract
This research endeavors to analyze the dynamic characteristics of the dobby, particularly the influence of a modulator on the dynamic response of the heald frame. By constructing precise kinematic and dynamic mathematical models and employing efficient computational algorithms, this study delves into the motion behavior of dobby. Component elastic deformation is considered, and a detailed analysis of the heald frame’s vibrational properties is conducted. With the establishment of dynamic and kinematic equations, coupled with Taylor series expansion and partial derivative techniques, the displacement errors were accurately calculated. The implementation of the fourth-order Runge–Kutta method facilitated numerical simulation, allowing for the analysis of the effect of cam profile errors on vibrational characteristics. The findings indicate that cam profile machining and system errors significantly influence the vibration amplitude under high-speed conditions. Consequently, this research highlights the imperative to control operating speeds in the design and operation of dobby and enhance vibration stability through precise machining of cam profiles, using high-precision equipment, and regular maintenance, which are essential for optimized design and improved stability and reliability.
Utility of dairy microbiome as a tool for authentication and traceability
Authors: Alvanou Maria V. , Loukovitis Dimitrios , Melfou Katerina , Giantsis Ioannis A. 
Published: October 2024

Abstract
Milk microbiome contributes substantially to the formation of specific organoleptic and physicochemical characteristics of dairy products. The assessment of the composition and abundance of milk microbiota is a challenging task strongly influenced by many environmental factors. Specific dairy products may be designated by the Protected Designation of Origin (PDO) and Protected Geographical Indication (PGI) labeling, which however, occasionally fail to differentiate them according to specific quality characteristics, which are defined by different microbiota-driven reactions. Combining the above limitations, the scope of the present study, was to summarize the existing information toward three main issues. First, to assess the influence level of the diet type and grazing to rumen–GI tract, mammary gland, and udder microbiome formation in ruminants. Second, to discuss the factors affecting milk microbiota, as well as the effect of the endo-mammary route on milk microbial taxa. Lastly, to evaluate “milk microbiome” as a tool for product differentiation, according to origin, which will contribute to a more robust PDO and PGI labeling. Although the limitations are still a matter of fact (especially considering the sample collection, process, evaluation, and avoidance of its contamination), significant progress has been made, regarding the identification of the factors affecting dairy products’ microbiota and its core composition. In conclusion, although so far not totally efficient in dairy products molecular identification, with the progress in soil, water, plant, and animal host’s microbiota assembly’s characterization, microbiomics could provide a powerful tool for authentication and traceability of dairy products.
Floer homology and right-veering monodromy
Authors: Baldwin John A. , Ni Yi , Sivek Steven 
Published: October 2024

Abstract
We prove that the knot Floer complex of a fibered knot detects whether the monodromy of its fibration is right-veering.
In particular, this leads to a purely knot Floer-theoretic characterization of tight contact structures, by the work of Honda–Kazez–Matić.
Our proof makes use of the relationship between the Heegaard Floer homology of mapping tori and the symplectic Floer homology of area-preserving surface diffeomorphisms.
We describe applications of this work to Dehn surgeries and taut foliations.
Time dependent model to analyze the magnetic refrigeration performance of gadolinium near the room temperature
Authors: Niu Jimei , Zheng Zhigang 
Published: October 2024

Abstract
A practical time-dependent model has been constructed to forecast the effectiveness and productivity of a magnetic regenerative refrigerator, as well as to assess its cycle efficiency. The model incorporates many irreversible factors, including the cycle frequency, heat transfer efficiency, and heat leak. Furthermore, it is utilized to scrutinize a magnetic refrigerator that employs spherical Gd particles as the magnetic substance and water as the heat transfer medium. The different cycle steps of the magnetic refrigerator are examined, while the cooling capacity and temperature differential between the two heat exchangers are appraised. The results also show that the magnetic refrigerator can obtain a temperature span of 5 K under 0.8 T magnetic field after 30 cycles in a particular situation. The findings provide valuable information for the future planning and advancement of magnetic refrigeration technology at room temperature.
Nanoscale engineering of semiconductor photocatalysts boosting charge separation for solar-driven H2 production: Recent advances and future perspective
Authors: Khan Khakemin , Rehman Zia Ur , Yao Shanshan , Bajpai Om Prakash , Miotello Antonio , Nawaz Mohsan , Orlandi Michele , Khan Khalid Ali , Alanazi Abdulaziz A. , Zaki Magdi E. A. 
Published: October 2024

Abstract
Photocatalytic hydrogen (H₂) production is regarded as an efficient method for generating renewable energy. Despite recent advancements in photocatalytic water splitting, the solar-to-hydrogen conversion efficiency of photocatalysts remains well below the 10% target needed for commercial viability due to ongoing scientific challenges. This review comprehensively analyzes recent advancements in nanoscale engineering of photocatalytic materials, emphasizing techniques to enhance photogenerated charge separation for efficient solar hydrogen production. Here we highlight the nanoscale engineering strategies for effective charge separation including crystal engineering, junction engineering, doping-induced charge separation, tailoring optoelectronic properties, hierarchical architecture, defects engineering, various types of heterojunctions, and polarity-induced charge separation, and discuss their unique properties including ferroelectric on spatial charge separation along with the fundamental principles of light-induced charge separation/transfer mechanisms, and the techniques for investigation. This study, critically assesses strategies for effective photogenerated charge separation to enhance photocatalytic hydrogen production and offers guidance for future research to design efficient energy materials for solar energy conversion.
The Pastoral Usefulness of Female Scriptural Speech in Origen of Alexandria
Authors: De Cock Miriam 
Published: October 2024

Abstract
In this article, I wish to build on the little work previously done on the theme of Origen and women by focusing on Origen’s exegetical treatment of the speech uttered by a selection of female scriptural characters. I focus on their speech as a way of applying the observations made by Mark Randall James in his 2021 monograph, Learning the Language of Scripture: Origen, Wisdom, and the Logic of Interpretation, concerning one of Origen’s primary exegetical goals, namely, to teach his pastoral-exegetical audience to become those who speak the words of scripture. I therefore focus on Origen’s exegetical treatment of Mary and Elizabeth in his Homilies on Luke, the mother of the 7 martyrs in his Exhortation to Martyrdom, the Samaritan woman at the well in the Commentary on John, the Canaanite woman in the Commentary on Matthew, and finally the bride of the Song of Songs in the Commentary on the Song of Songs. I demonstrate that Origen’s approach to this female scriptural speech was textured and complex. In some cases, Origen was not prepared to provide fitting contexts in which their words might be spoken by his audience, but in others, he could be found teaching his audience to use female characters’ words as exemplary prayers, as words of encouragement in the face of a situation that may lead to martyrdom, as exemplary modes of proclaiming Christ, and even in difficult exegetical contexts. This focus on female utterances in the scriptural record allows us to see how thoroughly pastoral was Origen’s exegesis, thus moving us beyond the idea that Origen used “the feminine” only for the sake of understanding complex theological and philosophical ideas.
The Impact of Competition Intensity on Software Security: An Empirical Analysis of Web Browser Patch Releases
Authors: Jo Arrah-Marie 
Published: October 2024

Abstract
This paper investigates the relationship between competition intensity and the security level provided by software vendors, in particular when the software is free of charge to users. We examine the case of web browsers, a key component of internet security where vendors compete on quality and generate revenue through advertising. Using a pooled cross-sectional dataset on web browser security patch releases from 2009 to 2018, we analyze how competition affects the promptness of these releases. Our findings reveal that higher market concentration can enhance a vendor’s responsiveness in addressing vulnerabilities, though this positive effect weakens when a vendor becomes excessively dominant.
A case of severe Covid-19 infection as the first manifestation of Cushing’s disease
Authors: Guia Lopes Maria Leonor , Cidade José Pedro , Antunes Carolina , Limbert Clotilde , Sequeira Duarte João 
Published: October 2024

Summary
Cushing's disease (CD) is characterized by distinct syndromic features, often accompanied by obesity and depression. However, considering its gradual onset of symptoms, it is usually associated with diagnostic delays. In rare instances, CD may lead to severe infections due to the observed immunosuppression in affected individuals. We present a rare case of an undiagnosed CD in a 20-year-old male with a medical history of depression and obesity, complicated by severe COVID-19 infection. He presented to the Emergency Room with respiratory distress, hypertensive crisis, and fever, ultimately receiving the diagnosis of SARS-CoV-2 pneumonia. The patient required mechanical ventilation and intensive care unit (ICU) admission due to severe acute respiratory distress syndrome (ARDS). During ICU care, he received remdesivir and dexamethasone, subsequently developing severe hyperglycemia and worsened hypertension, requiring insulin and multiple antihypertensive agents to manage metabolic disruption. Upon physical examination, classic signs of hypercortisolism were noted. Subsequent laboratory tests and pituitary magnetic resonance imaging confirmed the diagnosis of CD. The patient underwent surgical resection with significant improvements in body composition and metabolic parameters postoperatively. After surgery, remission of hypercortisolism was evident, accompanied by notable improvements in mood and overall health. This case underscores the importance of recognizing hypercortisolism in the context of metabolic, physical, and mood changes. Timely diagnosis of CD is crucial to mitigate complications such as severe opportunistic infections and their outcomes.

Learning points

Despite some hallmark features such as proximal myopathy, easy bruising, purple striae, and facial plethora, Cushing’s disease (CD) is a challenging diagnosis due to its nonspecific signs and symptoms and gradual onset.

The case emphasizes the importance of recognizing subtle signs of CD, such as social isolation, depressive symptoms, and changes in body composition, which may be confounded by external factors like the COVID-19 pandemic.

Patients with CD are prone to severe infections due to chronic hypercortisolism-induced immunosuppression.

CD diagnostic delays are common, leading to worsening of metabolic and immune dysfunction over time. Heightened clinical suspicion and early intervention are essential to prevent diagnostic delays and optimize patient outcomes.
Impact of shading devices on daylight performance using simulation analysis
Authors: Shih Rowell Ray Lim 
Published: October 2024

AbstractThis study examines the impact of various external shading devices on key lighting metrics, such as spatial daylight autonomy, annual sunlight exposure, and mean illuminance in classrooms. By comparing the performance of different shading options, the study offers insights into optimizing natural lighting, enhancing visual comfort, and improving sustainability in educational buildings in warm, humid climates. The findings provide valuable guidance for architects, designers, and school facility managers aiming to improve energy efficiency and occupant comfort in educational environments.
Modelos mentales en estudiantes universitarios acerca de Evolución
Authors: Díaz-Castro Ingry Johana 
Published: October 2024

La evolución no se abarca a profundidad porque las teorías propuestas son controvertidas y muchas veces se opone a las concepciones de docentes y estudiantes, lo que evidencia que en las áreas disciplinares de botánica y zoología no se implementa a profundidad el tema. Por lo tanto, se pretende conocer los modelos mentales de seis estudiantes de cuarto semestre de la Licenciatura en Biología de la Universidad Distrital Francisco José de Caldas sobre la evolución, tomando las percepciones como modelos mentales, según la teoría de Johnson- Laird, complementándose con la propuesta de preguntas mediadoras realizada por Márquez et al. (2004).

La información recopilada se obtiene mediante la investigación cualitativa, desde un paradigma hermenéutico interpretativo, usando el estudio de caso como tipo de investigación y la triangulación de datos para el análisis de la información. La indagación se desarrolla en tres fases que permiten conocer los modelos mentales de los estudiantes mediante un esquema gráfico, uno conceptual y una entrevista, que son trianguladas para el análisis de los datos obtenidos. Se demuestra la afinidad de los sujetos por el modelo sintético, por lo cual es necesario obtener modelos deducidos y subcategorías para acoger y categorizar todos los datos obtenidos. Finalmente, se establece el uso de conceptos que no solo se enmarcan en un modelo único establecido, lo que evidencia que los estudiantes usan los modelos mentales de acuerdo con el fenómeno al cual quieren darle explicación.
Generierung gekoppelter Materialflussmodelle
Authors: Kienzlen Annika , Verl Alexander 
Published: October 2024

In einer Produktionsanlage werden Stückgüter auf unterschiedliche Weise gehandhabt. Um den Transport zu testen und zu optimieren, kann eine virtuelle Inbetriebnahme (VIBN) durchgeführt werden. Basierend auf der Stückgüterart, den benötigten Arbeitsschritten und der Handhabung, sind dafür unterschiedliche Materialflussmodelle geeignet. Um den Modellierungsaufwand zu minimieren, soll eine gemeinsame Modellbasis entwickelt werden, aus der verschiedene Modelle generiert werden können. Das Ziel ist eine einmalige Modellierung des gesamten Materialflusses für eine Multi-Skalen-Materialflusssimulation.
Integration von K¨unstlicher Intelligenz in die Produktion
Authors: Schieseck Marvin , Topalis Philip , Gehlhoff Felix , Fay Alexander , Zech Tom , Ortloff Richard 
Published: October 2024

Dieser Artikel soll als Leitfaden fu¨r Praktiker dienen, die ihre eigenen KI-Anwendungen entwickeln wollen. Er deckt den ganzen Prozess von der Konzeption bis zur Realisierung ab. Um dies zu erreichen, wird eine bestehende Entwicklungsmethodik erweitert, um einen strukturierten Ansatz fu¨r den KI-Entwicklungsprozess zu bieten. Diese Struktur wird durch spezielle Schritte erreicht, die jeweils von spezifischen Handlungsempfehlungen begleitet werden. Daru¨ber hinaus wird jeder Schritt mit Methoden und Praktiken aus Forschung und Praxis angereichert, einschließlich grafischer Modellierungsansätze und Dokumentationstechniken. Dies gewährleistet einen robusten und gut dokumentierten Entwicklungsprozess, der die erfolgreiche Implementierung von KI-Lösungen im industriellen Umfeld erleichtert.
СРАВНИТЕЛЬНЫЙ АНАЛИЗ МЕТОДОВ ОЦЕНКИ ЭКОНОМИЧЕСКОЙ ЭФФЕКТИВНОСТИ ИНВЕСТИЦИЙ
Authors: Л.А. Селютин 
Published: October 2024

В статье представлен сравнительный обзор методов оценки экономической эффективности инвестиций. Актуальность темы обусловлена меняющимися экономическими условиями в современном мире, которые влияют на инвестиционную среду. Анализ методов оценки позволяет понять их устойчивость к переменам и возможность адекватно оценивать инвестиционные вложения. В статье рассматриваются ключевые характеристики инвестиций, подчеркивается важность экономической оценки инвестиций. Подробно анализируются различные методы инвестиционной оценки – статистический и динамические. Приводятся преимущества и недостатки каждого из методов с учетом специфики их применения при принятии инвестиционных решений. Также даются выводы относительно каждого метода при их использовании в процессе оценки инвестиций. Несмотря на свои ограничения, статические методы ценятся за их простоту, в то время как динамические методы эффективны с точки зрения определения реальной эффективности инвестиций, то есть с учетом стоимости денег во времени. В заключение подчеркивается взаимосвязь этих методов и необходимость их совместного рассмотрения для комплексной оценки эффективности инвестиций.
The article presents a comparative review of methods for assessing the economic efficiency of investments. The relevance of the topic is due to the changing economic conditions in the modern world, which affect the investment environment. Evaluation methods are analyzed to understand their resilience to change and the ability to adequately evaluate investment investments. The article considers the key characteristics of investments, emphasizes the importance of economic evaluation of investments. Different methods of investment evaluation – statistical and dynamic – are analyzed in detail. Advantages and disadvantages of each method are given, taking into account the specifics of their application in making investment decisions. The conclusions are also given regarding each method used in the investment appraisal process. Despite their limitations, the static methods are valued for their simplicity, while dynamic methods are effective in determining the real effectiveness of investments, i. e. taking into account the time value of money. In conclusion, the article emphasizes the interrelationship of these methods and the need to consider them together for a comprehensive evaluation of investment performance.
ТВОРЧЕСКИЙ ХАРАКТЕР ПРОИЗВЕДЕНИЯ КАК КРИТЕРИЙ ЕГО ОХРАНОСПОСОБНОСТИ
Authors: А.В. Павлов 
Published: October 2024

В статье рассматривается проблема применения критерия творчества к оценке охраноспособности произведения. Анализируются различные подходы современных авторов, специалистов по авторскому праву, к применению критерия творчества к произведениям разных видов (в том числе доктринальные подходы, применяемые в странах общего права) и делается вывод о том, что требует серьезного учета зарубежный опыт и необходим переход от подходов к формированию единого критерия творческого характера произведения к дифференцированному подходу в зависимости от специфики отдельных видов произведений.
The article addresses the problem of applying the criterion of creativity to the assessment of the work’s protectability. The author analyzes various approaches of modern copyright experts to the application of the creativity criterion to works of various types (including doctrinal approaches used in common law countries) and concludes that foreign experience requires serious consideration. It is necessary to make a transition from approaches using a single criterion of the creative nature of a work to a differentiated approach, which depends on the specifics of individual types of works.