bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proving in Geometry: A Sociocultural Approach to Constructing Mathematical Arguments Through Multimodal Literacies
Authors: Taylor Christine 
Published: June 2018

AbstractMultimodal literacies have been incorporated as social learning practices in content areas, but research regarding multimodality within secondary mathematics instruction has often lacked the sociocultural lens. The author describes practitioner action research in the form of a case study (with one focal participant) from a public high school. The author explored the use of multimodal literacies through geometry students’ projects, work samples, classroom videos, and interviews. Students created and presented arguments (through PowerPoint, Word, videos, and storybooks) on court cases in efforts to relate proving and justifying in geometry to evidence and claims in court. Findings reveal ways that multimodal literacies served as a vehicle for students to engage with their social context of learning in a mathematics classroom, demonstrating that sociocultural approaches to multimodal literacies can apprentice students into disciplinary literacy practices of mathematics. Moreover, these sociocultural perspectives toward multimodal literacies pose possible instructional applications in multiple content areas.
Prevalence of combined and noncombined dyslipidemia in an Iranian population
Authors: Darroudi Susan , Saberi‐Karimian Maryam , Tayefi Maryam , Arekhi Soheil , Motamedzadeh Torghabeh Ali , Seyedzadeh Sani Seyed Mohammad Reza , Moohebati Mohsen , Heidari‐Bakavoli Alireza , Ebrahimi Mahmoud , Azarpajouh Mahmoud Reza , Safarian Mohammad , A. Ferns Gordon , Esmaeili Habibollah , Parizadeh Mohammad Reza , Mokhber Naghme , Mahdizadeh Adeleh , Mahmoudi Ali Asghar , Sahebkar Amir Hossein , Ghayour‐Mobarhan Majid 
Published: June 2018

BackgroundCombination of dyslipidemic phenotypes, including elevated plasma levels of low‐density lipoprotein cholesterol (LDL‐C), elevated plasma triglycerides (TG), and decreased low‐density lipoprotein cholesterol (HDL‐C) concentrations, is important because of the association of individual phenotypes with increased risk of cardiovascular disease (CVD). We investigated the prevalence of combined dyslipidemias and their effects on CVD risk in an Iranian large population.MethodA total of 9847 individuals were recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) cohort study. Anthropometric parameters and biochemical indices were measured in all of the subjects. Different types of combined dyslipidemias including high TG + low HDL‐C, high TG + low HDL‐C + high LDL‐C, low HDL‐C + high LDL‐C, high TG + high LDL‐C, and finally high TG + high LDL‐C + low HDL‐C were considered. Ten‐year CVD risk was calculated using the QRISK2 risk algorithm and adjustments were made as suggested by the Joint British Societies’ (JBS2). Logistic regression analyses were performed to determine the association between different combined dyslipidemias and categorical QRISK.ResultsA total of 3952 males and 5895 females were included in this current study. Among the included subjects, 83.4% had one form of dyslipidemia, and 16.6% subjects were not dyslipidemic. The mean age was 48.88 ± 7.9 and 47.02 ± 8.54 years for dyslipidemic and nondyslipidemic groups, respectively. The results showed that the frequency of dyslipidemia was 98%, 87.1%, and 90% in subjects with metabolic syndrome, CVD, and diabetes, respectively. Our results suggested that around 15.7% of study population were at 10 years CVD risk (high ≥20) and it was higher in men than women (P < .001). Moreover, risk of CVD was higher in TG↑ & HDL↓ & LDL↑ group than other groups.ConclusionPrevalence of dyslipidemia was 83.4% among Iranian adults. The results showed that individuals with increased plasma TG and LDL‐C, and low HDL‐C levels had the highest 10 years CVD risk compared to other combined dyslipidemic phenotypes.
Significant association of PRMT6 hypomethylation with colorectal cancer
Authors: Pan Ranran , Yu Hang , Dai Jie , Zhou Cong , Ying Xiuru , Zhong Jie , Zhao Jun , Zhang Yihan , Wu Boyi , Mao Yiyi , Wu Dongping , Ying Jieer , Duan Shiwei 
Published: June 2018

BackgroundProtein arginine N‐methyltransferase 6 (PRMT6) was deemed to be indispensable in the variety of biological processes. Upregulated PRMT6 was found in various human diseases including cancer. Herein, we investigated the performance of PRMT6 methylation in the diagnosis for CRC.MethodsA quantitative methylation‐specific polymerase chain reaction (qMSP) method was used to measure PRMT6 promoter methylation. The percentage of methylated reference (PMR) was applied to represent gene methylation level.ResultsOur data indicated that PRMT6 promoter methylation levels were significantly lower in CRC tissues than those in paired nontumor tissues (median PMR: 36.93% vs 63.12%, P = 1E‐6) and normal intestinal tissues (median PMR: 36.93% vs 506.55%, P = 8E‐12). We further examined the potential role of PRMT6 hypomethylation by the receiver operating characteristic (ROC) curve. Our results showed that the area under the curve (AUC) was 0.644 (95% CI = 0.596‐0.733) between CRC tissues and paired nontumor tissues, 0.958 (95% CI = 0.919‐0.998) between CRC tissues and normal intestinal tissues, and 0.899 (95% CI = 0.825‐0.972) between paired nontumor tissues and normal intestinal tissues.ConclusionOur study firstly indicated that the hypomethylation of PRMT6 promoter could be a novel diagnostic biomarker for CRC.
Purification, characterization and potential applications of a novel halotolerant metalloprotease from marine bacterium Vibrio sp. LA‐05
Authors: Zhang Hong , Li Hui , Lang Dietmar A , Xu Hai , Zhu Hu 
Published: June 2018

AbstractBACKGROUNDMany reported proteases showed low activity and stability under harsh operating conditions, e.g. high pH, salinity and surfactants, which hinders expansion of their applications in industry. Here, a novel halotolerant metalloprotease from marine bacterium Vibrio sp. LA‐05 endowed with superior properties was purified and characterized, and its industrial application also evaluated.RESULTSThe protease was active and stable at 25–40°C and pH 6.0–10.0. Moreover, it was remarkably stable in high salt solution, tolerant to denaturing agents, organic solvents, surfactants and bleaching agents, and quite compatible and stable with many commercial detergents. Its residual activities were above 22% even after co‐incubation with 20% NaCl for 480 h. Except Ariel and Tide, the residual activities were all above 55% after co‐incubation with five other liquid detergents for 240 h. The corresponding theoretical analyses show that it is a metalloprotease containing 1 mol of zinc ion per mole of protease, the mature active protease predominantly in α‐helix form consists of 321 amino acids, and the central zinc ion along with 11 other conserved and crucial amino acid residues forms the catalytic domain.CONCLUSIONThese excellent properties indicated that the protease has considerable potential as a bio‐additive in the application of detergent formulations. © 2018 Society of Chemical Industry
Thyroid follicular carcinoma in a teenager: A case report
Authors: Oka Kosuke , Shien Tadahiko , Otsuka Fumio 
Published: June 2018

AbstractA 19‐year‐old girl complained of an enlarged cervical mass. Based on clinical and cytological assessments, it was diagnosed as thyroid follicular carcinoma and left thyroidectomy was performed. Although thyroid neoplasms are rare in young people, differentiation is needed when the rapid growth of a goiter is detected.
Transcriptome profiles of isolated murine Achilles tendon proper‐ and peritenon‐derived progenitor cells
Authors: Mienaltowski Michael J. , Cánovas Angela , Fates Valerie A. , Hampton Angela R. , Pechanec Monica Y. , Islas‐Trejo Alma , Medrano Juan F. 
Published: June 2018

ABSTRACTProgenitor cells of the tendon proper and peritenon have unique properties that could impact their utilization in tendon repair strategies. While a few markers have been found to aid in distinguishing progenitors cells from each region, there is great value in identifying more markers. In this study, we hypothesized that RNAseq could be used to improve our understanding of those markers that define these cell types. Transcriptome profiles were generated for pools of mouse Achilles tendon progenitor cells from both regions and catalogues of potential markers were generated. Moreover, common (e.g., glycoprotein, signaling, and proteinaceous extracellular matrix) and unique (e.g., cartilage development versus angiogenesis and muscle contraction) biological processes and molecular functions were described for progenitors from each region. Real‐time quantitative PCR of a subset of genes was used to gain insight into the heterogeneity amongst individual progenitor colonies from each region. Markers like Scx, Mkx, Thbs4, and Wnt10a were consistently able to distinguish tendon proper progenitors from peritenon progenitors; expression variability for other genes suggested greater cell type complexity for potential peritenon progenitor markers. This is the first effort to define Achilles tendon progenitor markers by region. Further efforts to investigate the value of these cataloged markers are required by screening more individual colonies of progenitors for more markers. Clinical Significance: Findings from this study advance efforts in the discernment of cell type specific markers for tendon proper and peritenon progenitor cells; insight into marker sets could improve tracking and sorting strategies for these cells for future therapeutic strategies. © 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:1409–1418, 2019.
Dental prostheses and tooth‐related factors
Authors: Ercoli Carlo , Caton Jack G. 
Published: June 2018

AbstractObjectivesThis narrative review summarizes the current evidence about the role that the fabrication and presence of dental prostheses and tooth‐related factors have on the initiation and progression of gingivitis and periodontitis.FindingsPlacement of restoration margins within the junctional epithelium and supracrestal connective tissue attachment can be associated with gingival inflammation and, potentially, recession. The presence of fixed prostheses finish lines within the gingival sulcus or the wearing of partial, removable dental prostheses does not cause gingivitis if patients are compliant with self‐performed plaque control and periodic maintenance. However, hypersensitivity reactions to the prosthesis dental material can be present. Procedures adopted for the fabrication of dental restorations and fixed prostheses have the potential to cause traumatic loss of periodontal supporting tissues. Tooth anatomic factors, root abnormalities, and fractures can act as plaque‐retentive factors and increase the likelihood of gingivitis and periodontitis.ConclusionsTooth anatomic factors, such as root abnormalities and fractures, and tooth relationships in the dental arch and with the opposing dentition can enhance plaque retention. Restoration margins located within the gingival sulcus do not cause gingivitis if patients are compliant with self‐performed plaque control and periodic maintenance. Tooth‐supported and/or tooth‐retained restorations and their design, fabrication, delivery, and materials have often been associated with plaque retention and loss of attachment. Hypersensitivity reactions can occur to dental materials. Restoration margins placed within the junctional epithelium and supracrestal connective tissue attachment can be associated with inflammation and, potentially, recession. However, the evidence in several of the reviewed areas, especially related to the biologic mechanisms by which these factors affect the periodontium, is not conclusive. This highlights the need for additional well‐controlled animal studies to elucidate biologic mechanisms, as well as longitudinal prospective human trials. Adequate periodontal assessment and treatment, appropriate instructions, and motivation in self‐performed plaque control and compliance to maintenance protocols appear to be the most important factors to limit or avoid potential negative effects on the periodontium caused by fixed and removable prostheses.
Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions
Authors: Papapanou Panos N. , Sanz Mariano , Buduneli Nurcan , Dietrich Thomas , Feres Magda , Fine Daniel H. , Flemmig Thomas F. , Garcia Raul , Giannobile William V. , Graziani Filippo , Greenwell Henry , Herrera David , Kao Richard T. , Kebschull Moritz , Kinane Denis F. , Kirkwood Keith L. , Kocher Thomas , Kornman Kenneth S. , Kumar Purnima S. , Loos Bruno G. , Machtei Eli , Meng Huanxin , Mombelli Andrea , Needleman Ian , Offenbacher Steven , Seymour Gregory J. , Teles Ricardo , Tonetti Maurizio S. 
Published: June 2018

AbstractA new periodontitis classification scheme has been adopted, in which forms of the disease previously recognized as “chronic” or “aggressive” are now grouped under a single category (“periodontitis”) and are further characterized based on a multi‐dimensional staging and grading system. Staging is largely dependent upon the severity of disease at presentation as well as on the complexity of disease management, while grading provides supplemental information about biological features of the disease including a history‐based analysis of the rate of periodontitis progression; assessment of the risk for further progression; analysis of possible poor outcomes of treatment; and assessment of the risk that the disease or its treatment may negatively affect the general health of the patient.Necrotizing periodontal diseases, whose characteristic clinical phenotype includes typical features (papilla necrosis, bleeding, and pain) and are associated with host immune response impairments, remain a distinct periodontitis category.Endodontic‐periodontal lesions, defined by a pathological communication between the pulpal and periodontal tissues at a given tooth, occur in either an acute or a chronic form, and are classified according to signs and symptoms that have direct impact on their prognosis and treatment.Periodontal abscesses are defined as acute lesions characterized by localized accumulation of pus within the gingival wall of the periodontal pocket/sulcus, rapid tissue destruction and are associated with risk for systemic dissemination.
Hypercrosslinked polymeric restricted access materials for analysis of biological fluids
Authors: Popov Alekxander , Blinnikova Zinaida K. , Tsyurupa Maria P. , Davankov Vadim A. 
Published: June 2018

AbstractNew restricted access materials based on microporous hypercrosslinked polystyrene have been developed. The materials are aimed to use as packings for solid‐phase extraction cartridges to isolate low‐molecular‐weight analytes from biological fluids (for instance, blood plasma or serum). Two features distinguish these polymers from all known restricted access materials. The first one consists of the microporous hypercrosslinked polystyrene that not only exclude proteins from the sorbent phase but also do not adsorb them on the bead outer surface, and so they do not cause coagulation of blood protein components. Therefore, these materials do not require any chemical modification. The second distinguishing feature is the ability of hypercrosslinked sorbents to take up a wide variety of polar and nonpolar organic compounds. The sorbents were obtained in the form of beads of 60–70 μm in diameter by cross‐linking styrene copolymers with 1, 2, and 3% divinylbenzene with monochlorodimethyl ether to 100, 150, and 200% cross‐linking degree. The sorbents exhibit all typical properties of hypercrosslinked networks. They do not take up albumin, the major blood protein, and cytochrome C, representative of smaller protein molecules, but are capable of adsorbing drugs, vitamins, and phenyl carboxylic acids (markers of sepsis) from model aqueous solutions.
Influence of climate and land use changes on recent trends of soil erosion rates within the Russian Plain
Authors: Golosov Valentin , Yermolaev Oleg , Litvin Leonid , Chizhikova Nelli , Kiryukhina Zoya , Safina Gusel 
Published: June 2018

AbstractThe Russian Plain (within the Russian Federation) occupies an area of approximately 3.5 × 106 km2. Water erosion is the main land degradation factor within the Russian Plain. Previous quantitative assessments of erosion rates for the entire area of the Russian Plain were undertaken in the 1980s. The application of erosion models and analysis of different factor dynamics allow for the evaluation of the mean annual total soil losses and erosion rates for the post‐Union of Soviet Socialist Republics period, as well as the determination of the trends of erosion rates and soil losses for different landscape zones, for 1980 and 2012. The significant reductions of cultivated land area in all of the landscape zones after 1991 are the main reason behind the 46% reduction in the total annual soil losses in 2012 compared with 1980. The most significant decrease in the soil erosion rate for cultivated lands (from 7.3 Mg ha−1 yr−1 in 1980 to 4.1 Mg ha−1 yr−1 in 2012) was identified in the forest zone of the Russian Plain. Soil erosion rates slightly decreased in the forest‐steppe zone and increased in the steppe zone (from 3.9 to 4.6 Mg ha−1 yr−1). We attribute the decreasing erosion rates in the forest and forest‐steppe zones to the reduction of surface runoff during snowmelt. The increased use of perennial grasses in crop rotations promoted the reduction of erosion rates in the forest zone. The increasing erosion rates in the steppe zone were attributed to the increasing frequency of heavy rainstorms.
Angular Optical Transparency Induced by Photonic Topological Transitions in Metamaterials
Authors: Huo Pengcheng , Liang Yuzhang , Zhang Si , Lu Yanqing , Xu Ting 
Published: June 2018

AbstractPhotonic topological transitions (PTTs) in metamaterials open a new realm of research with a number of interesting optical phenomena and provide an efficient route to manipulate light–matter interactions at nanoscale. Here, it is shown that, by tailoring the topology of anisotropic metamaterial's equi‐frequency surface, a narrow angular optical transparency window appears around the PTT frequency, which makes the metamaterial strongly discriminate the light based primarily on the angle of incidence. In experimental implementation, a large‐scale nanowire metamaterial is fabricated by bottom‐up approach and achieves a highly transparent window with a narrow angular range at visible frequency. Based on this angular transparency effect, the metamaterial is further demonstrated to be capable of significantly suppressing the diffraction and interference of the light scattered from arbitrarily shaped objects and projecting their diffraction‐limited images into far field. These features make the metamaterials hold promise for a series of angle‐dependent optical applications.
Identification and characterization of new Muscodor endophytes from gramineous plants in Xishuangbanna, China
Authors: Mao Li‐Juan , Chen Jia‐Jie , Xia Chen‐Yang , Feng Xiao‐Xiao , Kong De‐Dong , Qi Zhen‐Yu , Liu Feng , Chen Dian , Lin Fu‐Cheng , Zhang Chu‐Long 
Published: June 2018

AbstractThe endophytic fungi Muscodor spp. produce volatile organic compounds (VOCs) which can inhibit and even kill pathogenic fungi, bacteria, and nematodes. Nine endophytic fungal strains, isolated from the shoots of gramineous plants including Arthraxon hispidus, Eleusine indica, Oplismenus undulatifolius, and Oryza granulata, were identified as Muscodor through phylogenetic analysis of the internal transcribed spacer. Through an SPSS K‐means cluster analysis, the nine Muscodor strains were divided into four groups based on the antifungal activities of the VOCs produced by these fungi determined by a two‐section confrontation test. The first group contains the strains Y‐L‐54, W‐S‐41, Y‐S‐35, W‐T‐27, and Y‐L‐56, which showed the strongest activity. The second and third groups contain W‐S‐35 and Y‐L‐43, which showed stronger and moderate activity, respectively. The fourth group contains W‐S‐38 and N‐L‐7, which were the weakest in inhibiting the tested pathogens. Thirty‐five compounds and the relative amounts of VOCs were determined by SPME‐GC‐MS and comparison with the NIST14 mass spectrometry database and Agilent MassHunter qualitative and quantitative analyses. These 35 compounds were classified into two different categories: (a) the product of fatty acid degradation, and (b) the intermediate and final metabolite of the metabolic pathway with the precursor of mevalonic acid. SPSS clustering analysis showed that the chemical components of VOCs might be correlated with their bioactivity rather than their phylogenetic assignment and some of the identified compounds might be responsible for antifungal activity. In conclusion, new Muscodor endophytes were recorded in tropical gramineous plants and a number of strains showed remarkable bioactive properties. Therefore, they have important potential applications in the fields of plant disease control.
Towards perfect NMR: Spin‐echo versus perfect‐echo building blocks
Authors: Parella Teodor 
Published: June 2018

AbstractThe development of new tools to improve the quality of nuclear magnetic resonance (NMR) spectra is a challenging task. The concept of “perfect NMR” includes the design of robust pulse sequences that allow an investigator to obtain undistorted pure in‐phase signals, with pure absorption lineshapes that are free of phase anomalies derived from undesired J modulations. Here, alternative NMR building blocks to the spin‐echo that are based on a general double SE module, known as a perfect‐echo, are reviewed. Several implementations to minimize/remove unwanted dispersive contributions in homonuclear and heteronuclear NMR experiments are described and illustrated with some examples of broad interest for small molecules.
Chemomechanical and morphological properties with proliferation of keratinocyte cells of electrospun poyhydroxyalkanoate fibers incorporated with essential oil
Authors: Tanadchangsaeng Nuttapol , Kitmongkolpaisarn Stayu , Boonyagul Sani , Koobkokkruad Thongchai 
Published: June 2018

Delivery systems based on electrospun polymeric nanofibers have shown potential for delivery of bioactive and plant extract formulations. This research focused on the fabrication of polyhydroxyalkanoate (PHA) copolymer nanofibers as a vehicle for loading of the Thai traditional herbal extract of Plai oil (Zingiber cassumunar Roxb). Nanofibers were formed by dissolving PHA and Plai oil together in dichloromethane solvent, with the PHA concentration being varied (5, 8, and 10%), followed by electrospinning for 4 hours. Based on the submicron diameters of the nanofibers, 8% PHA proved to be the optimal concentration. The concentration of Plai oil (10, 20, and 30%) was used, and hence, the solution viscosity influenced the nanofiber synthesis and physical properties of the nanofibers were obtained. Scanning electron microscope results indicated that the average diameters of cylindrical PHA nanofibers loaded with Plai oil (10%, 20%, and 30%) were 1.10, 1.01, and 1.11 μm, respectively, highlighting that fibers composed of 20% Plai oil were classifiable as nanofibers. Tensile testing of 20% Plai oil‐loaded nanofibers indicated that stiffness and elongation at break were within the acceptable range. Fourier transform infrared and differential scanning calorimetry measurements highlighted the presence of terpenen‐4‐ol, a component found in Plai oil, in the nanofiber film samples of PHA/Plai oil, confirming its inclusion in the systems. In addition, cell proliferation was set up to confirm the morphology and toxicity of skin keratinocyte cell line, and the results show that the HaCaT cells were attached on the PHA nanofibers which the nanofibers containing 20% Plai oil may affect cell behavior in spite the fact that it is not toxic to the cells.