bluuebunny/crossref_metadata_2025_split huggingface dataset:
Archaeobotanical Investigations at the Mid-5th Millennium BCE Pile-Dwelling Site of Ploča Mičov Grad, Lake Ohrid, North Macedonia
Authors: Holguin Amy , Antolín Ferran , Charles Mike , Jesus Ana , Martínez Grau Héctor , Soteras Raül , Steiner Bigna L. , Stroud Elizabeth , Bogaard Amy 
Published: November 2024

AbstractAbundant, well-preserved, waterlogged macrobotanical remains were found in a thick cultural organic layer associated with the Late Neolithic pile-dwelling site of Ploča Mičov Grad, Lake Ohrid, North Macedonia. Located in a biogeographically transitional zone between Mediterranean, alpine and continental regions, and on a topographically accessible link between imposing mountain ranges, the site presents a valuable opportunity to explore how, with the movement of people, plant foods and/or ideas, new subsistence strategies were established in the area. Here, we present the first archaeobotanical results from this lakeshore settlement to investigate changing subsistence strategies. We find that during the Late Neolithic occupation phase lasting an estimated 100 years, populations at the site of Ploča Mičov Grad cultivated a range of cereals (particularly einkorn, emmer, and barley), pulses (including lentil, pea, and bitter vetch) and oil-seed crops (flax and opium poppy), alongside a variety of collected fruits and nuts (such as almond, pistachio, blackberries and strawberry). Crop processing techniques are inferred from the partially charred glume bases consistent with singeing of cereal ears to remove awns before dehusking and from the weed seeds which resemble those found in fine-sieving by-products. Using functional weed ecology, we infer that theagrosystem at Ploča Mičov Grad resembles high-input practices suggesting that cultivation was small-scale and labour-intensive. Such inferences are often not possible due to the preservation conditions of terrestrial assemblages, resulting in a lack of extensive weed datasets in the southwestern Balkans and southern Europe more broadly. Archaeobotanical research on wetland prehistoric sites from this region is currently limited. Our new work highlights the potential of such sites in this area for better understanding of the spread ofagriculture and patterns of plant food use during the Neolithic in the southwestern Balkans.
Neolithic and Bronze Age Pile-Dwellings at Lake Ohrid: Underwater Excavations at Ploča Mičov Grad (North Macedonia)
Authors: Reich Johannes , Hostettler Marco , Ballmer Ariane , Hafner Albert 
Published: November 2024

AbstractOne of the regions of Europe where archaeological lakeshore sites or so-called pile-dwellings are found is the tripoint of Albania, Greece and North Macedonia, which includes dozens of known lakeshore sites on and in different lakes. One of the aims of the ERC Synergy Project EXPLO is the systematic underwater archaeological investigation of key pile-dwelling sites in this region. Currently, more than a dozen prehistoric lake- or river shore sites from the Neolithic and the Bronze and Iron Ages are known in the area surrounding the lakes of Ohrid, Prespa and Maliq (Fig. 5.1) (Naumov in Plattform 23:10–20, 2016; Andoni et al. in New Archaeological Discoveries in the Albanian Regions. Procedings of the International Conference, Tirana 30–31 January 2017. Botimet Albanologjike, Tirana, pp 123–140, 2017; Oberweiler et al. in Bulletin Archéologique Des Écoles Françaises à L’étranger 2020; Lera et al. in Bulletin archéologique des Écoles françaises à l’étranger 2020). Several of these sites still show waterlogged archaeological layers, in which organic matter and wooden construction elements are well preserved. However, only a few are systematically investigated and the number of absolute dates for most of the sites is still rather low. This paper summarises the recent archaeological fieldwork conducted by the University of Bern in partnership with the Museum of Ohrid and the Center for Prehistoric Research in Skopje on the site Ploča Mičov Grad in North Macedonia based on the publications of Hafner et al. (J Archaeol Sci Rep 38, 2021) and Reich et al. (J Archaeol Sci Rep 39, 2021) as well as new preliminary results of the ongoing research. We focus on ongoing research that has provided the first absolute chronologies of Neolithic and Bronze Age settlements at Lake Ohrid (Hafner et al. J Archaeol Sci Rep 38, 2021). The main methodology relies on both dendrochronological and radiocarbon datings. This high precision dating, in combination with studies of the material culture, contributes to a better chronological understanding of the prehistory of the surrounding basins and the southwestern Balkans in general.
Imagining Schooling as a Positive Experience: Conclusions and Practical Recommendations
Authors: Hargreaves Eleanore , Buchanan Denise , Quick Laura 
Published: November 2024

AbstractThis final chapter brings together our interpretations of CLIPS children’s life-histories and suggests implications for imagining schooling as a positive experience which promotes wellbeing. We indicate how the theories of Fraser from political science and Ryan and Deci from social psychology enriched our understandings of both wellbeing; and social justice synergies between the two; when applied to the CLIPS data. Watkins’ pedagogical distinction between learning and performance in schooling allowed us to draw well-targeted implications out of our data—in particular because children’s own voices informed and directed these. This rich set of sources added insights into our psychological understandings of children’s motivational Orientations in schooling which appear to be dependent on all children being constantly supported to have a strong Sense of Competence, Autonomy (Agency) and Relatedness. They highlight too how influences of a global performative schooling system influence individual children’s everyday experiences, often leading those who are lower-attainers in mathematics and English to experience status subordination. In this chapter, we present some implications of the life-histories in relation specifically to the following aspects of social justice: Redistribution, suggesting transformative remedies at national or international level; and Recognition and Representation, providing affirmative remedies at school and classroom level.
Sense of Competence and CLIPS children’s Experiences of the Policy Focus on Mathematics and English
Authors: Hargreaves Eleanore , Buchanan Denise , Quick Laura 
Published: November 2024

AbstractChapter 7 focuses on the Sense of Competence. This is, a key theme in our study of a group of children who have been categorised systemically as lacking in competence in relation to two prioritised subjects: mathematics and English. In this chapter, we look first at the historical background to the focus on such narrow areas of competence in the primary-school curriculum and then on the wider influences leading to this curriculum narrowing. We review literature indicating how demotivating the two ‘core’ subjects may be to some children. We then provide verbatim quotations from our sample of 23 children to illustrate which factors particularly eroded their Sense of Competence in these two areas—which all the children had found tricky—and we compare these experiences to other areas of learning that the children were intentionally engaged with, such as nature study, art, computers and sport. We portray some troubling descriptions by the children of the anxiety, distress and fear that accompanied many of their experiences of mathematics and English at school. We conclude by pointing out how policy documents emphasising grades in mathematics and English often fail to take account of the children’s needs for wellbeing to accompany their school-work, which is only likely to be experienced when competence, autonomy and relatedness are all promoted on an ongoing basis.
Project Case: Sino-German Platform for Precision Oncology—Tailor-Made Trainings for Medical Professionals
Authors: Porsche Sabine , Cui Shuo 
Published: November 2024

AbstractMalignant tumour has been the leading cause of death among disease-related deaths for a decade in China, and the incidence and mortality rate of all types of cancers in China are both higher than the worldwide average level (National Bureau of Statistics of China (2020). Annual data, statistical database. Retrieved from: http://www.stats.gov.cn/english/Statisticaldata/AnnualData/ [06.11.2020].). According to the National Cancer Center, 7.5 people were diagnosed with cancer every minute, and there were 2.338 million cancer deaths in 2015 (National Cancer Centre (2019). National cancer report. Retrieved from: https://www.cn-healthcare.com/article/20190623/content-520594.html. [06.11.2020].). In 2018, the three leading forms of cancer among new cases were lung (18.1 per cent), colorectum (12.2 per cent) and stomach (10.6 per cent) (International Agency for Research on Cancer, WHO (2018). Number of new cases in 2018, both sexes, all ages. Retrieved from: https://gco.iarc.fr/today/data/factsheets/populations/160-china-fact-sheets.pdf [06.11.2020].).
Multidisciplinary Investigation on How Avatars and Devices Affect Human Physiology
Authors: Kawaoka Shinpei , Izumi Yoshihiro , Nakata Keisuke , Haruno Masahiko , Tanaka Toshiko , Sumioka Hidenobu , Achanccaray David , Nakae Aya 
Published: November 2024

AbstractThe development of Cybernetic Avatars (CAs) will change our lives dramatically. Such a rapid evolution of new technologies is advantageous but also raises concerns, such as addiction. Herein, we present a new scientific issue regarding how to investigate the effects that using CAs throughout our lives has on our physiology. In this chapter, we discuss how avatars and devices affect human physiology at multiple levels, from gene expression to brain activity. We insist that our multidisciplinary investigation of how CAs affect us will be critical for the further development of our CA society.
Field Experiments in the Real World
Authors: Miyashita Takahiro , Kumazaki Hirokazu , Nishio Shuichi , Hirano Takashi , Arakawa Shinichi , Sodeyama Yoshinao 
Published: November 2024

AbstractThis chapter explores social-field experiments of cybernetic avatars (CAs). Previous chapters introduced the research and development initiatives necessary to achieve a society where individuals can actively participate remotely by operating CAs. To understand the feasibility of social participation through CA utilization, one approach is to conduct experiments in real-world scenarios and evaluate their effectiveness. In the Avatar Symbiotic Society Project, a variety of real-world validation experiments are being conducted across different countries, industries, sectors, teleoperators, and user demographics. This chapter outlines the essential elements for conducting social–field experiments and highlights those done in the fields of nursing care, mental health, and elderly support.
Machine Learning Algorithms to Predict the Risk of Rupture of Intracranial Aneurysms: a Systematic Review
Authors: Daga Karan , Agarwal Siddharth , Moti Zaeem , Lee Matthew B. K. , Din Munaib , Wood David , Modat Marc , Booth Thomas C. 
Published: November 2024

Abstract

Purpose
Subarachnoid haemorrhage is a potentially fatal consequence of intracranial aneurysm rupture, however, it is difficult to predict if aneurysms will rupture. Prophylactic treatment of an intracranial aneurysm also involves risk, hence identifying rupture-prone aneurysms is of substantial clinical importance. This systematic review aims to evaluate the performance of machine learning algorithms for predicting intracranial aneurysm rupture risk.

Methods
MEDLINE, Embase, Cochrane Library and Web of Science were searched until December 2023. Studies incorporating any machine learning algorithm to predict the risk of rupture of an intracranial aneurysm were included. Risk of bias was assessed using the Prediction Model Risk of Bias Assessment Tool (PROBAST). PROSPERO registration: CRD42023452509.

Results
Out of 10,307 records screened, 20 studies met the eligibility criteria for this review incorporating a total of 20,286 aneurysm cases. The machine learning models gave a 0.66–0.90 range for performance accuracy. The models were compared to current clinical standards in six studies and gave mixed results. Most studies posed high or unclear risks of bias and concerns for applicability, limiting the inferences that can be drawn from them. There was insufficient homogenous data for a meta-analysis.

Conclusions
Machine learning can be applied to predict the risk of rupture for intracranial aneurysms. However, the evidence does not comprehensively demonstrate superiority to existing practice, limiting its role as a clinical adjunct. Further prospective multicentre studies of recent machine learning tools are needed to prove clinical validation before they are implemented in the clinic.
“I spend more time on the ecosystem than on the disease”: caring for the communicative loop with everyday ADM technology through maintenance and modification work
Authors: Scott Hansen Sne , Langstrup Henriette 
Published: November 2024

AbstractAutomated decision-making (ADM) systems can be worn in and on the body for various purposes, such as for tracking and managing chronic conditions. One case in point is do-it-yourself open-source artificial pancreas systems, through which users engage in what is referred to as “looping”; combining continuous glucose monitors and insulin pumps placed on the body with digital communication technologies to develop an ADM system for personal diabetes management. The idea behind these personalized systems is to delegate decision-making regarding insulin to an algorithm that can make autonomous decisions. Based on interviews and photo diaries with Danish “loopers”, this paper highlights two interrelated narratives of how users have to care for the loop by maintaining a stable communication circuit between body and ADM system, and by modifying the loop through analysis and reflection. It shows how the human takes turns with the ADM system through practical doings and anticipation to safeguard continuous management of chronic disease.
Spin-Bounded Correlations: Rotation Boxes Within and Beyond Quantum Theory
Authors: Aloy Albert , Galley Thomas D. , Jones Caroline L. , Ludescher Stefan L. , Müller Markus P. 
Published: November 2024

AbstractHow can detector click probabilities respond to spatial rotations around a fixed axis, in any possible physical theory? Here, we give a thorough mathematical analysis of this question in terms of “rotation boxes”, which are analogous to the well-known notion of non-local boxes. We prove that quantum theory admits the most general rotational correlations for spins 0, 1/2, and 1, but we describe a metrological game where beyond-quantum resources of spin 3/2 outperform all quantum resources of the same spin. We prove a multitude of fundamental results about these correlations, including an exact convex characterization of the spin-1 correlations, a Tsirelson-type inequality for spins 3/2 and higher, and a proof that the general spin-J correlations provide an efficient outer SDP approximation to the quantum set. Furthermore, we review and consolidate earlier results that hint at a wealth of applications of this formalism: a theory-agnostic semi-device-independent randomness generator, an exact characterization of the quantum (2, 2, 2)-Bell correlations in terms of local symmetries, and the derivation of multipartite Bell witnesses. Our results illuminate the foundational question of how space constrains the structure of quantum theory, they build a bridge between semi-device-independent quantum information and spacetime physics, and they demonstrate interesting relations to topics such as entanglement witnesses, spectrahedra, and orbitopes.
The parasitic copepod, Sarcotretes scopeli Jungersen, 1911 castrate its mesopelagic fish host Benthosema glaciale
Authors: Andersen Ø. , Glenner H. , Salvanes A. G. V. 
Published: November 2024

AbstractThe mesopelagic fish Benthosema glaciale [Actinopterygii: Myctophiformes: Myctophidae], abundant in open ocean and deep fjords, is targeted for future exploitation despite existing knowledge gaps on population vital rates. Among these gaps, the vulnerability to pathogens is poorly understood. Parasites rely on the metabolic energy of their host and infections might compromise host physiology and behaviour, which in turn, may affect growth and survival. Parasitic infections by the copepod Sarcotretes scopeli [Crustacea: Copepoda: Pennellidae] have frequently been recorded from the North Atlantic, including west Norwegian fjords. In this paper we present data on how S. scopeli infection affect reproductive investment, energetic status, and growth of its host, the mesopelagic fish B. glaciale. Our results indicate that (i) S. scopeli reduce reproductive investment (measured as gonadosomatic index GSI) of both female and male B. glaciale; (ii) that the energy storage (hepatosomatic index HSI) appeared unaffected in female B. glaciale, while infected male hosts have higher HSI than uninfected, and (iii) that infected fish are in poorer condition than uninfected. These findings may indicate that S. scopeli could have a significant regulatory impact on B. glaciale populations.
Towards streamlined product information: reporting of transporter-mediated drug interactions
Authors: Asmar Valeria , Bergman Erik , Lindhagen Elin , Sherwood Kim , Westman Gabriel , Gaugaz Fabienne Zdenka 
Published: November 2024

Abstract
Purpose
The purpose of this study is to investigate the reporting of risks associated with transporter-mediated drug-drug interactions (DDIs) in medicinal product information and to identify suitable wording for future standardisation of summaries of product characteristics (SmPCs).

Methods
The SmPCs of medicinal products approved in the European Union from 2012 to 2023 were screened for warnings on Organic Anion Transporting Polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3), and Breast Cancer Resistance Protein (BCRP). An in-house search engine for product information was used. Warnings were categorised into different DDI scenarios based on the SmPC texts.

Results
A total of 192 out of 859 approved medicinal products had SmPC text pertaining to OATP1B1, 1B3 and/or BCRP. The majority of products had text for all three transporters Most texts were located in SmPC Sect. 5.2, followed by Sect. 4.5. Numerous interaction-texts either concluded that the interaction lacked clinical relevance or lacked information on the clinical relevance of the finding. The highest number of SmPC texts indicating a clinically relevant interaction with outlined clinical consequences was found for BCRP. The article also presents SmPC texts for each DDI scenario, which the authors consider as examples of explicit wordings with actionable recommendations.

Conclusion
A potential for improvement of SmPC text for transporter-mediated DDI was identified: Warnings without clinical relevance could be omitted, and some warnings with clinical relevance could be updated to provide actionable recommendations to the prescribers. A selection of unambiguous texts was identified as starting point to generate standard texts.
The impact of different radiology report formats on patient information processing: a systematic review
Authors: van der Mee F. A. M. , Ottenheijm R. P. G. , Gentry E. G. S. , Nobel J. M. , Zijta F. M. , Cals J. W. L. , Jansen J. 
Published: November 2024

Abstract
Background
Since radiology reports are primarily written for health professionals, patients may experience difficulties understanding jargon and terminology used, leading to anxiety and confusion.

Objectives
This review evaluates the impact of different radiology report formats on outcomes related to patient information processing, including perception, decision (behavioral intention), action (actual health behavior), and memory (recall of information).

Methods
PubMed, Web of Science, EMBASE, and PsycInfo were searched for relevant qualitative and quantitative articles describing or comparing ways of presenting diagnostic radiology reports to patients. Two reviewers independently screened for relevant articles and extracted data from those included. The quality of articles was assessed using the Mixed Methods Appraisal Tool.

Results
Eighteen studies, two qualitative and sixteen quantitative, were included. Sixteen studies compared multiple presentation formats, most frequently traditional unmodified reports (n = 15), or reports with anatomic illustrations (n = 8), lay summaries (n = 6) or glossaries (n = 6). Glossaries, illustrations, lay summaries, lay reports or lay conclusions all significantly improved participants’ cognitive perception and perception of communication of radiology reports, compared to traditional reports. Furthermore, these formats increased affective perception (e.g., reduced anxiety and worry), although only significant for lay reports and conclusions.

Conclusion
Modifying traditional radiology reports with glossaries, illustrations or lay language enhances patient information processing.

Key Points
QuestionIdentifying the impact of different radiology report formats on outcomes related to patient information processing to enhance patient engagement through online access to radiology reports.
FindingsLay language summaries, glossaries with patient-oriented definitions, and anatomic illustrations increase patients’ satisfaction with and understanding of their radiology reports.
Clinical relevanceTo increase patients’ satisfaction, perceived usefulness and understanding with radiology reports, the use of lay language summaries, glossaries with patient-oriented definitions, and anatomic illustrations is recommended. These modifications decrease patients’ unnecessary insecurity, confusion, anxiety and physician consultations after viewing reports.
Advancements in non-destructive archaeometric analysis of ancient ferrous artefacts: insights from SR-X-Ray diffraction investigation using model alloys
Authors: Galai Leila , Bérard Emilie , Réguer Solenn , Foy Eddy , Mocuta Cristian , Toffolon-Masclet Caroline , Guilbert Thomas , Dillmann Philippe 
Published: November 2024

AbstractThe exploration of archaeological heritage aims at understanding past societies through the study of ancient materials. While archaeometric analysis provides valuable insights, invasive sampling raises ethical concerns and is often restricted, necessitating the development of non-invasive techniques. This study presents a methodology based on X-Ray Diffraction using synchrotron radiation. The approach involves the elaboration and characterization of model alloys, with X-ray data analysis using Rietveld refinement and Williamson-Hall plot method. Phase identification along with crystallographical investigations conducted on three medieval armours provides insights into manufacturing techniques and highlights the method’s limitation.