bluuebunny/crossref_metadata_2025_split huggingface dataset:
O BELO ENQUANTO ESPLENDOR DO UM NO TRATADO I, 6 DE PLOTINO
Authors: Leonardi Vinícius José Henrique da Costa 
Published: July 2019

A partir do tratado Sobre o Belo (I, 6), de Plotino, é discutida no presente artigo a afinidade entre as vias estética e intelectiva como modo de acesso à união com o Um. Para tanto, propomos que o Belo seja entendido como um esplendor do Um, ou seja, como o que se manifesta concomitante e dependente do Um, atraindo para este o olhar daquele que empreende a ascensão filosófica. Assim, procuramos demonstrar que o Belo se fundamenta na intelecção da unidade, e que a ascensão ao Um é tanto estética quanto intelectiva.PALAVRAS-CHAVE: Estética. Alma. Experiência mística. Ascensão. Plotino. From the treaty On Beauty (I 6), by Plotinus, the affinity between the aesthetic and intellectual paths as a way of accessing the union with the One is discussed in this article. For that, we propose that the Beauty be understood as a splendor of the One, that is to say, as that one who manifests concomitant and dependent on the One, attracting to the latter the look of one who undertakes the philosophical ascension. Thus, we seek to demonstrate that the Beauty is based on the intellection of unity, and that the ascension to the One is both aesthetic and intellectual. Keywords: aesthetic; soul; mystical experience; ascension; Plotinus.
Developing a Theoretical Framework for Evaluating the Quality of mHealth Apps for Adolescent Users: A Systematic Review
Authors: Jeminiwa Ruth N. , Hohmann Natalie S. , Fox Brent I. 
Published: July 2019

OBJECTIVE To assess adolescents' preferred mobile app features and to propose a framework for evaluating health-related mobile apps for adolescents.
METHODS PubMed, CINAHL, PsycINFO, ERIC, HealthIT.gov, and ClinicalTrials.gov were systematically searched in August 2017. Studies pertaining to app development, feasibility, or usability that reported preferred app features and rating criteria on mHealth (mobile health) apps intended for adolescents were included. Quality assessment was performed using the Mixed Methods Appraisal Tool. Qualitative synthesis was performed to develop themes reflecting best practices for evaluating the quality of mHealth apps for adolescents. Using a grounded theory approach, we constructed a theoretical framework of rating criteria that can be used to inform development of an evaluation tool for mHealth apps targeted to adolescents.
RESULTS Thirteen articles were included. Most commonly preferred features include ability to track test results or self-management progress, connect to social media, and gain points or prizes through app gamification. Common rating criteria include degree of app customizability, ease of use, visual appeal, and interactivity. Five emerging dimensions were used in the theoretical framework: Technical Quality; Engagement; Support System; Autonomy; and Safety, Privacy, and Trust.
CONCLUSIONS We found that adolescents prefer mHealth apps that are customizable, offer peer support through social media, sustain engagement via gamification, and support the ability to visualize health trends via simplified graphs. Findings may help in the development of mHealth apps that are preferred by adolescents, as well as the development of a quality evaluation tool for mHealth apps targeted to this population.
Vancomycin Treatment Failure in Children With Methicillin-Resistant Staphylococcus aureus Bacteremia
Authors: Regen Rebecca B. , Schuman Sarah S. , Chhim Rebecca F. , Arnold Sandra R. , Lee Kelley R. 
Published: July 2019

OBJECTIVES Limited data exist regarding clinical outcomes of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections in children treated with vancomycin. Treatment success in adults correlates best with an area under the curve/minimum inhibitory concentration (AUC24/MIC) ratio ≥400. It is unknown if this relationship is useful in children.
METHODS Charts of children who received vancomycin ≥5 days for MRSA bacteremia with a steady state trough were reviewed. AUC24/MIC ratios were estimated using 2 different vancomycin clearance equations. Vancomycin treatment failure was defined as persistent bacteremia ≥7 days, recurrent bacteremia within 30 days, or 30-day mortality.
RESULTS There were 67 bacteremia episodes in 65 patients. Nine (13.4%) met failure criteria: persistent bacteremia (n = 6), recurrent bacteremia (n = 2), 30-day mortality (n = 1). There were no differences between patients receiving &lt;60 mg/kg/day and ≥60 mg/kg/day of vancomycin in median trough (11.9 versus 12.3 mg/L, p = 0.1). Troughs did not correlate well with AUC24/MIC ratios (R2 = 0.32 and 0.22). Patients receiving ≥60 mg/kg/day had greater probability of achieving ratios ≥400. There were no significant differences in median dose (p = 0.8), trough (p = 0.24), or AUC24/MIC ratios (p = 0.07 and p = 0.6) between patients with treatment success and failure.
CONCLUSIONS Treatment failure was lower than previously reported in children. AUC24/MIC ratios ≥400 were frequently achieved but were not associated with treatment success, dose, or troughs. Prospective studies using standard definitions of vancomycin treatment failure are needed to understand treatment failure in children with MRSA bacteremia.
Effectiveness of Levetiracetam as a First-Line Anticonvulsant for Neonatal Seizures
Authors: Kreimer Alexander M. , Littrell Robert A. , Gibson Julia B. , Leung Noelle R. 
Published: July 2019

OBJECTIVE Optimal treatment for neonatal seizures remains unclear, and management among US hospitals is highly varied. The purpose of this study was to evaluate the effectiveness of levetiracetam as a first-line treatment for seizures in a neonatal population.
METHODS A single-center, retrospective review of neonates at a tertiary medical center who received levetiracetam as a first-line agent after benzodiazepines for seizure control between 2015 and 2017 was conducted. Chart review was completed to analyze patient and treatment characteristics. The primary outcome was seizure control, defined as clinical seizure cessation and video electroencephalogram resolution, with no new seizures documented prior to discharge.
RESULTS A total of 36 patients met inclusion criteria. Seventeen patients (47%) had seizure control after intravenous levetiracetam as monotherapy. Eighteen patients required a second anticonvulsant, of which 13 (72%) had seizure control. In total, 30 patients (83%) had seizure control with levetiracetam monotherapy or combination therapy of levetiracetam plus fosphenytoin or phenobarbital.
CONCLUSIONS Levetiracetam monotherapy provided seizure control in about 50% of the patients reviewed. Overall, seizure control was observed in 83% of the study population that received either levetiracetam monotherapy or combination therapy of levetiracetam plus fosphenytoin or phenobarbital as a second-line agent. Further studies are warranted to directly compare historical therapies with levetiracetam for neonatal seizure control.
Limitações do gerenciamento dos resíduos sólidos urbanos em município de pequeno porte
Authors: Leite Ana Paula , Nogueira Thaís Helena Leite , Edwiges Thiago , Rech Angela Laufer 
Published: July 2019

A problemática envolvendo os resíduos sólidos é um dos problemas que a administração pública enfrenta, uma vez que o gerenciamento inadequado gera impactos negativos tanto econômicos, quanto ambientais e sociais. Assim, o objetivo do estudo consistiu em diagnosticar e propor diretrizes para o gerenciamento dos resíduos sólidos urbanos (RSU) do município de Matelândia/PR. Para tanto, realizou-se um levantamento quali-quantitativo dos RSU gerados no município por meio da determinação da composição gravimétrica dos resíduos destinados ao aterro sanitário municipal, foram obtidos dados de geração per capita diária e densidade dos resíduos; análise das condições ambientais da destinação adotada, conforme a avaliação de aterros de resíduos e condições das cooperativas de catadores, índice da qualidade dos resíduos (IQR) e índice de coleta seletiva (ICS), respectivamente. Os dados foram coletados in loco e análise da percepção ambiental dos munícipes desenvolvida com base na aplicação de entrevistas e elaboração de mapas temáticos gerados conforme as respostas obtidas. Os resultados mostraram que são dispostos, em média, 2,9 toneladas de resíduos no aterro sanitário, sendo que, 31% são resíduos orgânicos, 24% rejeitos, 18% outros, 9% plásticos, 8% papel e papelão, 4% metal e 1% vidro. A densidade dos resíduos foi calculada em 128 kg.m-3 e a geração per capita em 672 kg.dia-1. O IQR obtido foi de 5,0 e o ICS foi de 4,2, classificando as condições de operação como inadequadas, dentro das suas relativas faixas de classificação. Ao todo, foram entrevistadas 542 residências, destas, 66% afirmaram não saber a destinação final dada aos RSU, 22% indicaram o aterro sanitário e 12% o lixão. A regulamentação do cronograma da coleta convencional e seletiva, adequação da infraestrutura operacional do aterro sanitário e melhoria nas condições de trabalho dos associados da cooperativa de catadores foram as proposições estabelecidas de acordo com o diagnóstico. As informações levantadas dos RSU fornecem ao gestor público não apenas o volume de resíduos gerados, mas, um panorama do manejo que abrange desde a geração (nas residências) até a destinação final (aterro e associação de reciclagem). A partir dos aspectos, sejam estes positivos ou negativos, o gestor público tem suporte para realizar o planejamento de ações corretivas e/ou preventivas.
La sabiduría del corazón. “Una esfera giróvaga, una estrella viajera”
Authors: Twinch Cecilia 
Published: July 2019

El mundo entero es a la par incesante levante y poniente, una esfera giróvaga, una estrella viajera que se manifiesta entre la salida y la puesta por una auto-revelación divina, que es la orden dirigida a ella para que se torne manifiesta u oculta, y una revelación del ser individual (revelation of self), que es lo que el Real busca de ella y lo que ella busca del Real.Las obras de Ibn ʿArabī están a cada línea impregnadas de recuerdos del amor de Dios y de Su compasión hacia Su creación, así como de la belleza deslumbrante y el exquisito sabor de la realidad. Si consideramos que los escritos de Ibn ʿArabī son significativos para nosotros hoy en día, es preciso examinar lo que nos dicen acerca de nuestras preocupaciones actuales, ahora que cada vez nos hacemos más conscientes de la unidad de la humanidad, reunida en esta tierra donde continuamente está saliendo y poniéndose el sol para tantos seres humanos con quienes podemos entrar en contacto desde donde quiera que nos encontremos. Tanto es así que cada vez más lo local y particular se ve reflejado en lo global y universal [...]
Jung e o Islam: contribuições à diversidade religiosa
Authors: De Oliveira Marcos Fleury 
Published: July 2019

Muitos daqueles que já escutaram o canto do adān podem ter se sensibilizado bastante ou, pelo menos, podem ter sentido algo diferente, estranho, estrangeiro. Mas, antes de mais nada, devemos esclarecer que o adan não é propriamente considerado uma música, mas um chamado feito cinco vezes por dia em todo o mundo muçulmano para lembrar e congregar os fiéis nos horários de oração. Minha intenção aqui é justamente lembrar um pouco dessa estranheza porque ela é parte de um sentimento muito forte descrito por Jung ao ter contato pela primeira vez com os povos muçulmanos do norte da África, há quase um século atrás. Essa estranheza ainda hoje constitui-se como um sentimento que o “ocidente” experimenta em relação ao “oriente” e é também um sentimento que parte do ocidente experimenta também com relação aos muçulmanos e ao Islam. Independente do fato de que sejamos crentes ou ateus, o entendimento que temos sobre Deus, a religião ou a fé, terá um peso considerável no modo como enxergamos muitos dos conflitos atuais. Para trabalhar essa questão e apresentar alguns elementos importantes para a superação dessa dissociação histórica com o “outro”, o estranho, o estrangeiro (concreto e simbólico), vou trazer algumas ideias do psicólogo suíço Carl Gustav Jung e do místico andaluz Ibn ʿArabī. Tentarei mostrar como ideias e autores aparentemente tão dispares podem dialogar entre si e nos oferecer novas perspectivas para a reflexão contemporânea. Comecemos com Freud e Jung.
Dios con nosotros: sobre la noción de maʽiyya en el esoterismo islámico
Authors: Lameiro Máximo 
Published: July 2019

En el taṣawwuf esoterismo islámico se encuentra la noción denominada maʽiyya. Palabra árabe formada por la sustantivación o nominalización de la partícula maʽa: con. A partir de su fuente coránica la maʽiyya divina no sólo ha sido objeto de profundas elaboraciones teóricas, sino que ocupa un lugar dentro de las prácticas espirituales del taṣawwuf. Aquí, nos limitaremos a exponer muy someramente la significación teórica de la maʽiyya, especialmente respecto a la cuestión religiosa de la relación de Dios con la criatura, y a la cuestión ontológica del lugar de dicha criatura dentro del orden del ser. Pero, el modo en que la gnosis islámica entiende ambas cuestiones escapa de las representaciones religiosas y filosóficas ordinarias al respecto. Desde esta perspectiva se dice que Dios, al manifestarse a Sí mismo, conoce las innumerables posibilidades de ser implícitas sin dualidad ni extrinsecación en Su propia esencia, en tanto dicha esencia es infinita y no carece de nada ni está limitada por nada. Dios conoce en Sí mismo todo lo que puede ser, lo que ha de ser y lo que nunca será.
Gestación de la razón inspirada: agnosia infinita
Authors: Piñas Saura Carmen 
Published: July 2019

Ibn ʿArabī y María Zambrano hacen aparecer lo que quieren decir en el horizonte de nuestra conciencia sugiriendo, llamando nuestra atención hacia un lugar de resonancia poética que es receptáculo profundo donde la palabra como semilla comienza a germinar. En Zambrano este proceso se intensifica a raíz de su experiencia abisal; experiencia mística, su vivencia de la guerra civil. Al respecto, las palabras del maestro Agustín Andreu: “Ortega dedica la vida a aclarar la circunstancia, Machado entrega la vida a la circunstancia. Zambrano se come la vida y la circunstancia”.
IbnʿArabī: el viaje exterior y el viaje interior
Authors: Mora Fernando 
Published: July 2019

Ιbn ʿArabī fue un viajero incansable que recorrió todo el mundo musulmán de su época. Partiendo de su ciudad natal, Murcia, conoció todo Al-Ándalus y el Magreb almohades y el Oriente Medio abasí. En su peregrinación por la Vasta Tierra de Allah también realizó un viaje interior en una búsqueda, a todas luces consciente y precursora de su viaje exterior, del sello de la santidad muhammadí que le llevó a experimentar un Viaje Nocturno mahomético y la Ascensión. No obstante, esto sólo constituye la mitad del camino e Ibn ʿArabī lo recorrió entero: regresó a la vida cotidiana para ayudar a los demás con sus enseñanzas.
Arte y símbolo:La perspectiva metafísica
Authors: Martínez Albarracín Francisco 
Published: July 2019

En la obra del gran maestro sufí, Ibn ʿArabī, el simbolismo y el arte son de gran importancia. El árbol y la montaña son dos símbolos esenciales que se repiten en la obra del maestro. Nuestro artículo tiene como objetivo hacernos entender el arte del tiempo en el que vivió Ibn ʿArabī así como su propia concepción de la belleza o la poesía. Plantearemos aquí algunos rasgos principales de la concepción tradicional del arte, manifiesta en todo el mundo antiguo, así como el arte oriental y de la Edad Media. El arte, esencialmente, como representación de los objetos de acuerdo con su naturaleza, ya que ésta contiene de un modo virtual la belleza. El arte como expresión del conocimiento, al ser las obras de arte soportes para la contemplación en la medida en que expresan y aluden a realidades invisibles. Así, “la tarea del arte consiste en aprehender la verdad primordial, en hacer audible lo inaudible, en enunciar la palabra primordial. En la concepción metafísica del arte, los símbolos constituyen su lenguaje universal, su sustancia, pues el contenido de los símbolos es esencialmente metafísico. Un símbolo es el único medio de expresar lo que no puede ser percibido por los sentidos de otra forma. A través de los símbolos podemos tomar contacto con el latido cordial del Alma del mundo, que dibuja las formas de las cosas. Ibn ʿArabī abre nuestro universo a perspectivas infinitas, mediante una lógica oriental sustentada en una coherente angelología y una doctrina de los Nombres divinos. El símbolo “se sumerge en el inconsciente y se eleva a lo supraconsciente”; “se apoya en la experiencia íntima y en la tradición”. Tiene un valor de puente pues se trata de un lenguaje universal que habla a cada uno, como en un espejo, ya que el símbolo “se comunica sólo en proporción de la apertura y las capacidades personales”.En el Islam, el simbolismo no solo se encuentra en la literatura sino también en la arquitectura. En cuanto al simbolismo arquitectónico y arte islámico, todo edificio, construido según los criterios del arte tradicional, nos ofrece en su estructura y en la disposición de sus elementos un significado cósmico. En todas las construcciones encontramos referencias simbólicas cargadas de sentido. Así, el conjunto de un edificio expresa el equilibrio, esto es, el reflejo de la Unidad en el orden cósmico; la parte poligonal se puede poner en relación con las facetas de las cualidades divinas, mientras que la cúpula evoca la Unidad indiferenciad. Por otro lado, ese espíritu geométrico, tan característico del arte musulmán evoca el pasaje de la Unidad indivisible a la «Unidad en la multiplicidad» o a la «multiplicidad en la Unidad» como en la serie de figuras geométricas regulares contenidas en el círculo o la de los polígonos regulares contenidos en la esfera.
STROBE-MR: Guidelines for strengthening the reporting of Mendelian randomization studies
Authors: Davey Smith George , Davies Neil M , Dimou Niki , Egger Matthias , Gallo Valentina , Golub Robert , Higgins Julian PT , Langenberg Claudia , Loder Elizabeth W , Richards J Brent , Richmond Rebecca C , Skrivankova Veronika W , Swanson Sonja A , Timpson Nicholas J , Tybjaerg-Hansen Anne , VanderWeele Tyler J , Woolf Benjamin AR , Yarmolinsky James 
Published: July 2019

While the number of studies using Mendelian randomization (MR) methods has grown exponentially in the last decade, the quality of reporting of these studies often has been poor. Similar to other reporting guidelines such as CONSORT (Consolidated Standards of Reporting Trials) for randomised trials and STROBE (STrenghtening the Reporting of Observational studies in Epidemiology) for observational studies in epidemiology, the STROBE-MR working group aims to provide guidance to authors on how to improve reporting of MR studies and help readers, reviewers, and journal editors to evaluate the quality of the presented evidence.
Empirical evidence indicates that many reports of MR studies do not clearly state or examine the various assumptions of MR methods and report insufficient details on the data sources, which makes it hard to evaluate the quality and reliability of the results. The STROBE-MR guidance covers both one sample and two sample MR studies. At present, the draft checklist consists of 20 items, organized into the title and abstract, introduction, methods, results and discussion sections of articles.
As these guidelines aim to reach the entire MR community, we would like to give everyone the opportunity to contribute their comments. The following draft of the STROBE-MR checklist is open for public discussion and all feedback will be taken into account during its next revision. For feedback, please use the comment section below this post on PeerJ Preprints.
We hope the final guidelines will serve the entire community and contribute to improving the reporting of MR studies in the future.
Comparison of integrated PET/MRI with PET/CT in evaluation of endometrial cancer: a retrospective analysis of 81 cases
Authors: Bian Li-hua , Wang Min , Gong Jing , Liu Hong-hong , Wang Nan , Wen Na , Fan Wen-sheng , Xu Bai-xuan , Wang Ming-yang , Ye Ming-xia , Meng Yuan-guang 
Published: July 2019

Background
The objective of this study was to compare the diagnostic value of integrated PET/MRI with PET/CT for assessment of regional lymph node metastasis and deep myometrial invasion detection of endometrial cancer.

Methods
Eighty-one patients with biopsy-proven endometrial cancer underwent preoperative PET/CT (n = 37) and integrated PET/MRI (n = 44) for initial staging. The diagnostic performance of PET/CT and integrated PET/MRI for assessing the extent of the primary tumor and metastasis to the regional lymph nodes was evaluated by two experienced readers. Histopathological and follow-up imaging results were used as the gold standard. McNemar’s test was employed for statistical analysis.

Results
Integrated PET/MRI and PET/CT both detected 100% of the primary tumors. Integrated PET/MRI proved significantly more sensitivity and specificity than PET/CT in regional lymph node metastasis detection (P = 0.015 and P < 0.001, respectively). The overall accuracy of myometrial invasion detection for PET/CT and Integrated PET/MRI was 45.9% and 81.8%, respectively. Integrated PET/MRI proved significantly more accurate than PET/CT (P < 0.001).

Conclusion
Integrated PET/MRI, which complements the individual advantages of MRI and PET, is a valuable technique for the assessment of the lymph node metastasis and myometrial invasion in patients with endometrial cancer.
A green garlic (Allium sativum L.) based intercropping system reduces the strain of continuous monocropping in cucumber (Cucumis sativus L.) by adjusting the micro-ecological environment of soil
Authors: Xiao Xuemei , Cheng Zhihui , Lv Jian , Xie Jianming , Ma Ning , Yu Jihua 
Published: July 2019

The continuous cropping obstacle of cucumber (Cucumis sativus L.) under facility cultivation is more prevalent in China. This is associated with an imbalance in soil microbial and ecological environment in long-term monocultures. It was postulated that intercropping with green garlic would relieve the continuous cropping obstacle of cucumber by altering the soil micro-ecology status. A pot-based experiment was conducted to investigate the green garlic-cucumber intercropping and cucumber monocropping systems. The results showed that the cucumber shoot biomass was improved by intercropping with green garlic. However, the population of soil bacteria and actinomycetes increased, while the fungal population decreased. The fatty acid methyl ester (FAME) profiles indicated that soil contained more fungal FAME biomarkers (18:1ω9c, 18:2ω6, 9) and higher fungal:bacterial ratio in the monoculture system, whereas clustering of more bacterial FAME biomarkers (cy17:0, cy19:0, 16:1ω7c10, Me16:0, 10Me17:0, 10Me18:0) was observed under intercropping conditions. Moreover, significantly (P < 0.05) higher soil invertase and alkaline phosphatase activities, organic matter, and available N, P and K contents were observed under intercropping systems. These were high in both bulk and rhizosphere soils in the intercropping system when compared to monocropping system. These findings suggest that intercropping with green garlic can alleviate continuous cropping obstacle of cucumber by improving the diverse composition of soil microbial community, enzyme activities, and nutrient availability.