bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosocial Risk Factors in Ambulatory Patients With Arterial Hypertension and Ischemic Heart Disease of 30 Cities in Russia: Data from the КОМЕТА (Сomet) Study
Authors: Pogosova N. V. , Boitsov S. A. , Oganov R. G. , Kostyuk G. P. , Sokolova O. Yu. , Yufereva Yu. M. , Kursakov A. A. , Ausheva A. K. , Vygodin V. A. , Karpova A. V. , Arutyunov A. А. , Isakova S. S. 
Published: November 2018

Background.Psychosocial (PS) risk factors (RF) make a substantial contribution in populational burden of cardio-vascular diseases (CVD) and their complications.Purpose.The KOMETA (Comet) study was directed to obtaining actual information on PSRF among ambulatory patients with arterial hypertension (AH) and / or ischemic heart disease (IHD) in 30 cities of Russian Federation.Materials and methods.This multicenter cross-sectional study was conducted in 2016–2017. Doctors participating in the study (n=325) recruited in state polyclinics 2775 patients aged ≥55 years with AH and / or IHD. Information collected from these patients comprised social-demographic and clinical characteristics, data on RF, adherence to therapy. Assessment of PSRF was carried out with consideration of levels of anxiety, depression and stress, presence of personality type D. Results. Population of patients studied (72 % women) was characterized by considerable prevalence of PSRFs. Low levels of education and income were found in 24.5 and 44.2 % of patients, respectively; 25.2 % of patients reported living alone, 6.3 % – felt social isolation. Elevated, extremely high levels of stress, type D personality were detected in 67.8, 10, and 37.6 % of patients, respectively; clinically significant symptoms of anxiety and depression were found in 25.5 and 16.3 %, respectively. Most RFs were significantly more often detected in women, and older people. One third of patients (33.1 %) during a year preceding inclusion took some psychotropic drugs mainly herbal or barbiturate-containing (27.1 %). Moreover, 30 % of patients had lowering of cognitive functioning.Conclusion.In this large-scale study we revealed high prevalence of PSRFs among ambulatory patients with AH and / or IHD in Russia. Despite positive dynamics of prevalence of states of anxiety and depression relative to earlier studies in this country their negative impact on prognosis of CVD and quality of life of affected patients requires optimization of efforts for organization of adequate care and directed to timely diagnosis and correction of these states.
Study the effect of mifepristone on clinical symptoms and its side effects in patients with fibroid uterus
Authors: Seher Umbreen , Chauhan Nidhi , Mangla Mishu 
Published: November 2018

Background: Fibroid can lead to a variety of clinical symptoms including pain, menorrhagia, and lump in abdomen. The availability of a safe and efficient medical management options for symptomatic fibroid is of considerable clinical and public health importance. The present study is designed to see the safety and efficacy of mifepristone in the medical management of uterine fibroids.Methods: The study was conducted in the Department of Obstetrics and Gynaecology, Himalayan Institute of Medical Sciences, Swami Ram Nagar, Dehradun over a period of 12 months. A total of 40 patients were included in the study.Results: Amount of bleeding was assessed by PBAC score, which significantly reduced by 83.9% at the end of treatment. And 62% patients developed amenorrhoea due to mifepristone. Similarly, pain abdomen/dysmenorrhoea was assessed by Numeric Pain Rating Scale, which also showed a significant reduction in 55% patients with no pain at the end of 3 months.Conclusions: The study clearly shows that Mifepristone is a safe and effective option to manage fibroid uterus and its associated symptoms.
PAP smear in pregnancy: a hospital-based study
Authors: Priya S. Senthil , Shankar R. 
Published: November 2018

Background: Pregnant and non-pregnant women are at similar risk for CIN and cervical cancer. The incidence of abnormal cervical cytologic findings during pregnancy is 0.72 to 1.67%. Approximately 86% of all squamous intraepithelial lesions (SIL) indentified during pregnancy are classified as low-grade SIL, whereas 14% are high- grade SIL. The aim of this study is to assess the incidence of Pap smear abnormalities among antenatal woman presenting to present hospital.Methods: A prospective study was conducted in present medical college hospital in the department of Obstetrics and Gynecology for a period of one year from Jan 2017 to Dec 2017. A total of 200 antenatal women were included in the study. Ayre’s spatula was used to conduct smear tests in this study. All smears were immediately sprayed with a fixative and sent to the department of Pathology. The cytological results were reported based on the Bethesda classification system 2001.Results: The pap smear report revealed that 26% of the subjects had inflammatory changes and for 66% it showed negative for intraepithelial lesion and for only 1% of the subjects had signs related to carcinoma cervix in which one patient had Atypical Squamous Cell of Undetermined Significance (ASCUS) and another patient had Low-grade Squamous Intraepithelial Lesion (LSIL) and no satisfactory sample was able to be obtained in 6% of the subjects. In present study authors found a statistically significant association between the age at marriage and the pap smear report, lower the age at marriage (<20 years) higher the incidence of inflammatory changes in the cervix and both the patients who were reported with ASCUS and LSIL were in the age of 15 and 16 years respectively.Conclusions: Clinicians should make every effort to educate, counsel and screen pregnant women if they have not had a Pap test in the past.
Mimicking reproductive endocrinology to achieve successful pregnancy in frozen embryo replacement cycle in luteinized unruptured follicle (LUF
Authors: Jain Namita , Malik Sonia , Prakash Ved 
Published: November 2018

Frozen embryo replacement cycles are commonly performed in all ART centres for various indications. In FER cycles, aim is to achieve the synchronization between the endometrium and the embryo. It can be undertaken in a natural or in an artificially prepared endometrium. Artificial preparation utilizes either the ovulation induction agents or hormones. Luteinized unruptured follicle is commonly encountered nowadays due to better resonance USG machines and frequent monitoring. It is still unclear among the practitioners whether to perform an embryo transfer in LUF. In this case report, authors are highlighting that in case of FER cycles using ovulation induction agent, despite inability to ovulate (LUF), if authors are able to achieve optimum synchronization between endometrium and the embryo using USG and serum hormonal levels, successful outcome could be expected.
Comparison of carbetocin with other uterotonic agents in preventing postpartum hemorrhage
Authors: Carlisa Belinda 
Published: November 2018

Postpartum hemorrhage (PPH) is defined as blood loss of at least 500 ml or more after vaginal delivery and 1000 ml or more after abdominal delivery. It contributes up to 28% of maternal mortality worldwide and 30.3% of maternal death in Indonesia. 70% cases of PPH are caused by uterine atony. PPH can be prevented by doing routine use of uterotonic agents in active management of third stage of labour. Uterotonic agents that currently available are oxytocin, carbetocin, methylergometrine, syntometrine, misoprostol and carboprost. Carbetocin (a long-acting synthetic analogue of oxytocin) is a new drug which has stronger ability to induce uterine contraction than oxytocin. It does not induce hypertension like methylergometrine and syntometrine. Therefore, carbetocin can be considered as an alternative drug to oxytocin in women with severe preeclampsia. However, more studies are needed to assess the efficacy and safety of carbetocin for prevention of PPH in preeclamptic women. Compared to methylergometrine and syntometrine, carbetocin is more effective in reducing postpartum blood loss. Adverse effects like nausea and vomiting were lower in women treated with carbetocin. Compared to misoprostol, carbetocin is also superior in reducing blood loss. Adverse effects like shivering, fever and metallic taste were higher in women treated with misoprostol. Further studies are needed to assess the superiority between carbetocin and carboprost since there is no published literature yet regarding this topic. In conclusion, carbetocin is superior to other uterotonic agents in preventing postpartum hemorrhage with fewer adverse effects.
Cancer vaccines: a newer front of immunotherapy
Authors: Puri Sonia , Goel Naveen Krishan , Chadha Veenal , Bhandari Praizy 
Published: November 2018

Vaccines have been used as a promising instrument over the years to combat the dreadful communicable diseases. But now owing to epidemiological transition as the burden of non-communicable diseases has increased, efforts are now being made globally to use this weapon for non-communicable diseases like cancer. Cancer vaccines belong to a class of substances known as “biological response modifiers”. These work by stimulating or restoring the immune system’s ability to fight infections and disease. There are two broad types of cancer vaccines: Preventive (or prophylactic) vaccines and Treatment or therapeutic vaccines. Cancer treatment vaccines are made up of cancer cells, parts of cells or pure antigens. Sometimes a patient’s own immune cells are removed and exposed to these substances in the lab to create the vaccine. Cancer treatment vaccines differ from the vaccines that work against viruses. These vaccines try to get the immune system to mount an attack against cancer cells in the body. Instead of preventing disease, they are meant to get the immune system to attack a disease that already exists. Preventive vaccines are intended to prevent cancer from developing in healthy people. And in fact, many evidence-based studies have proven the decrease in morbidity and mortality in various cancers by usage of some of the vaccines like cervical cancer vaccine etc. The biggest challenges currently facing preventive anti-cancer vaccines are clinical, social, and economic in nature. This article is an effort to highlight the advances in various cancer vaccines, so done, to use them on preventive and therapeutic front.
A Conservative Treatment Approach to Unilateral Sinusitis with a Cutaneous Fistula
Authors: Ventin Ramón , Martín Silvia , Juarez Inma , Mesalles Antonio , Lopez del Moral Javier , Lopez Piriz Roberto 
Published: November 2018

Abstract:
The rehabilitation of severely resorbed maxillae containing zygoma implants is a non-grafting treatment option that presents many advantages for patients. It is not, however, free from complications and the most frequent of those reported in the literature is sinusitis. A cutaneous fistula is a less frequent complication, but one that requires more than routine dental treatment and usually calls for maxillofacial surgery. Here, we present the case of a 64-year-old male suffering from sinusitis and with a cutaneous periorbital fistula as a complication; this occurred 8 years after the patient received dental rehabilitation with zygomatic implants. This clinical report suggests that the trans-sinusal hemisection of zygomatic implants to release the apical portion combined with transnasal inferior antrostomy offers a viable and effective mid-way treatment option between surgical procedures and the total removal of the implants. Keeping the prosthesis functional is the main advantage of this conservative approach to the treatment of sinusitis involving a cutaneous fistula in association with the restoration of zygomatic implants.
Accidents Increase in Inadequate Housing Conditions: A Cross-Sectional Study from Turkey
Authors: TEMEL Fehminaz , ACAR VAİZOĞLU Songül 
Published: November 2018

Objectives: Housing is
an important determinant of health, and substandard housing is a major public
health issue. The aim of this study was to determine the prevalence of home
accidents, and to evaluate the associations between housing conditions and home
accidents in a health centre region in Ankara. Methods: In this
cross-sectional research, we collected data from a representative sample of 210
houses using two standard questionnaires, which was used in the WHO’s Large
Analysis and Review of European Housing and Health Status (LARES) project. In
total, 528 people participated. Home accidents were self-reported and questioned for the previous year. We
developed a composite index to assess the overall housing conditions. Housing
conditions were accepted “inadequate” if the score was below the median. We
developed a logistic regression model to predict the housing-related factors in
accidents.Results: Of the
participants, 60.4% were female, 89.0% had health insurance, and 56.1% were
married. Fifty-eight point three percent of the respondents were living in
inadequate housing conditions. The prevalence of home accidents during previous
year was 21.2%. The first three most common accident types were falls, cuts,
collision/striking and the mostly injured body parts were arm/upper limb,
leg/lower limb, surface area of the body. Some of the items which have been
involved in these accidents were construction features, kitchen equipment, and
knives. The accidents were more common among females, people who reported
fatigue, in kitchens with too little workplace and houses with noise
problems(p&lt;0.05). The odds of home accidents were 1.8 times more (95%
CI:1.1-2.8) among residents living in inadequate housing conditions. The
logistic model showed that, accidents were 2.1 times more (95% CI: 1.1-4.2) in
those living in houses where adaptations for physical constraints were lacking,
and 1.9 times more among females (95% CI: 1.1-3.3).

Conclusion: Home
accidents were common and related to housing conditions. We recommended that
factors that can cause accidents in residential buildings be taken into
consideration during the construction phase through cooperation of the
municipality, the construction sector and the health personnel. This will
enable everyone to benefit from these arrangements in the house.
La caja sin atributos, la ciudad cacofónica. La redefinición de la idea de significado en el cerramiento arquitectónico contemporáneo
Authors: Sánchez Lampreave Ricardo 
Published: November 2018

Resumen Durante la década final del siglo XIX y las primeras del pasado, y trascendiendo sus específicos valores, las culturas pictórica y literaria adelantaron lo que supondría la pérdida de capacidad significante de una arquitectura sin atributos. Desde entonces proliferaron las confiadas en que su cerramiento pudiera convertirse en un eficaz mecanismo de significación, y no ya su forma. Una extrañeza que inicialmente acarreó notables dificultades para que la arquitectura pudiera seguir expresando sus contenidos, abocada a redefinir la idea misma de significado. Dada su menguante posibilidad comunicativa y consiguiente reducción a mero soporte, los “textos” quedaron encargados de negociar con las técnicas de significación mediática la búsqueda de la máxima persuasión y la más rápida información en el complejo marco de la ciudad. La interpretación moderna de la arquitectura como una máquina terminó por convertir en cacofónica la anhelada sinfonía de la gran ciudad.AbstractIn the course of the last decade of the nineteenth-century and the early decades of the latter, and going beyond its specific values, visual and literary cultures put forward what would entail the loss of the signifier for a meaningless architecture without qualities. Since then, architectures that proclaimed its building envelope as an effective mechanism of meaning,and not exclusively its form, have proliferated. An oddity that initially led to considerable difficulties in order to allow architecture to continue expressing its contents, compelled to redefine the very notion of meaning. Given its diminishing communicative feasibility and its fall into a simple medium, “texts” were tasked to negotiate with media significance techniques in the search for maximum persuasion and prompt information within the city complex framework. A modern interpretation of architecture as machine ended up turning to cacophonous the big city longed-for symphony.
El discurso arquitectónico de Hassan Fathy Lo vernáculo desde una perspectiva moderna
Authors: Moreno Moreno María Pura 
Published: November 2018

Resumen La condición de arquitectura alternativa apunta a procesos individualistasalejados de convencionalismos de contexto. La internacionalización de los postulados modernos condujo a la crítica a eludir en sus análisis construcciones de revitalización de una arquitectura considerada comoexcesivamente identitaria. Este artículo analiza el esfuerzo del arquitectoegipcio Hassan Fathy (1900-1989) por reivindicar, a todas las escalas, lasabiduría de la edificación tradicional durante un periodo coincidente con la modernidad occidental. La escasez de hierro y cemento en Egipto, tras la II Guerra Mundial, fomentó la recuperación de una construcción de bajo coste adaptada a las circunstancias y recursos materiales del lugar. La durabilidad de la arquitectura popular que permanecía conservada desde tiempos remotos, y sobre todo su eficacia en el control climático, fomentó en Fathy el deseo de aprendizaje de métodos y dispositivos tradicionales tanto constructivos como espaciales que fueron reinterpretados con una lectura moderna, desde el ámbito doméstico al urbano, en la morfología y materialización de sus proyectos.AbstractThe “alternative” architectural condition points to individualistic processes that give results far removed from the conventionalisms of context. The internationalization of the modern postulates led the critique to leave constructive procedures in the analyses of revitalization of an architecture considered as excessively identitarian, to one side.This article analyses the effort of the Egyptian architect Hassan Fathy (1900-1989) to defend at all levels, during a period coinciding with Western modernity, the wisdom of traditional inherited edification.The scarcity of iron and cement in Egypt, after the Second World War, boosted the recovery of a low-cost construction adapted to the climatic conditions and the material resources available locally. Popular architecture’s durability, especially its utilitarian aspect, preservedsince ancient times and, in particular, its effectiveness in climate control, inspired in Fathy the desire to learn traditional constructive and spatial devices. The questioning of the figure of the “Muallim”, or Master Mason, which had become a source of inherited knowledge, with regards vernacular constructive systems, added to his own analysis of popular architecture, gave him a knowledge of autochthonous materials and passive mechanisms of environmental control that were reinterpreted with a modern reading in the materialization of both his domestic and urban projects.
Identifying untapped potential: a geospatial analysis of Florida and California's 2009 recycled water production
Authors: Archer Jana E. , Luffman Ingrid , Andrew Joyner T. , Nandi A. 
Published: November 2018

AbstractIncreased water demand attributed to population expansion and reduced freshwater availability caused by saltwater intrusion and drought, may lead to water shortages. These may be addressed, in part, by use of recycled water. Spatial patterns of recycled water use in Florida and California during 2009 were analyzed to detect gaps in distribution and identify potential areas for expansion. Databases of recycled water products and distribution centers for both states were developed by combining the 2008 Clean Water Needs Survey database with Florida's 2009 Reuse Inventory and California's 2009 Recycling Survey, respectively. Florida had over twice the number of distribution centers (n = 426) than California (n = 228) and produced a larger volume of recycled water (674.85 vs. 597.48 mgd (3.78 mL/d = 1 mgd), respectively). Kernel Density Estimation shows the majority of distribution in central Florida (Orlando and Tampa), California's Central Valley region (Fresno and Bakersfield), and around major cities in California. Areas for growth were identified in the panhandle and southern regions of Florida, and northern, southwestern, and coastal California. Recycled water is an essential component of integrated water management and broader adoption of recycled water will increase water conservation in water-stressed coastal communities by allocating the recycled water for purposes that once used potable freshwater.
Развитие взглядов на взаимосвязь произвольного движения и его мысленного образа
Authors: Kaminskiy Igor V. , Leonov Sergey V. 
Published: November 2018

Введение. Широко известно, что проработка двигательного навыка посредством мысленного представления способствует повышению его скоординированности и результативности. Однако образ рассматривался как гипотетическая основа произвольного движения еще до начала своего практического применения. Статья впервые представляет текущее понимание образа движения как разрешения противоречий, присущих более ранним взглядам, и рассматривает совместимость последних с современной точкой зрения, чем обосновывает необходимость пересмотра некоторых существующих рекомендаций по применению мысленного образа в спорте.
Теоретическое обоснование. Отправной точкой в рассмотрении мысленного образа как основы произвольного движения явилась идеомоторная теория. Моторным эффектам, описанным как неконтролируемое выражение доминирующей идеи, посвящены работы Т. Лэйкока и У. Б. Карпентера. Однако их видение как проявления системной роли образа в контроле движения пришло благодаря трудам И. Ф. Гербарта, Г. Р. Лотце и Э. Харлесса. Экспериментальное подтверждение подобных явлений было получено в ряде инструментальных исследований непроизвольной двигательной активности при ее мысленном представлении, которые поддержали научный интерес к идеомоторной теории в условиях ее критики со стороны бихевиоризма. Разрешение противоречий было предложено на современном этапе М. Джиннеродом, рассматривающим двигательный образ как осознанную репрезентацию лежащих в основе соответствующего движения нейрофизиологических процессов, которая формируется при отсутствии инактивирующей обратной связи от исполнительных органов.
Результаты и их обсуждение. Современное понимание двигательного образа фокусируется на его эквивалентности фактическому движению с точки зрения реализующих его центральных нейрофизиологических процессов и присущих ему свойств, в т. ч. формирования навыка при повторении соответствующего движения. Важную роль в двигательном обучении, особенно на начальных этапах, которую подчеркивал еще П. Ф. Лесгафт, играют когнитивный анализ движения и познание его смысловой структуры с помощью образа. При этом, как показывают исследования, когнитивные и моторные процессы тесно переплетены между собой.