bluuebunny/crossref_metadata_2025_split huggingface dataset:
Individual trust: does quality of local institutions matter?
Authors: Camussi Silvia , Mancini Anna Laura 
Published: October 2018

AbstractThis paper contributes to the literature on the determinants of trust by investigating how the quality of local services influences individuals’ generalized trust and trust in local governments. Using data from Italian national statistical office (Istat) Aspects of Daily Life survey, after building a new measure for the quality of local services, we study its effect on individuals’ trust using linear regressions techniques. Our findings suggest that good local public services have a positive impact on individuals’ trust, the effect being stronger for trust in local institutions. Our results are robust to potential endogeneity issues, tested using a two-step GMM estimation procedure, and to potential omitted variables bias, according to the method proposed by Altonji et al. (2005).
Prevalence of Bullying and Cyberbullying in the Last Stage of Primary Education in the Basque Country
Authors: Machimbarrena Juan Manuel , Garaigordobil Maite 
Published: October 2018

AbstractBullying and cyberbullying pose a serious problem in our schools. Despite this research area’s increasing relevance, most research into cyberbullying in the present day has focused only on adolescents. However, given the long-lasting effects of victimization, it is necessary to understand its prevalence throughout the different educational stages of students. This study aims to clarify the prevalence of bullying and cyberbullying among students in the 5th and 6th grades. A sample of 1,993 (Mage = 10.68, SD = 0.71; range 9–13) students completed the “Cyberbullying: Screening of Peer-Harassment” test. The results reveal that 20.3% (n = 404) were pure victims, 6.1% (n = 121) pure bullies, 23.9% (n = 476) bully-victims, and 28.9% (n = 575) pure bystanders of bullying. With respect to cyberbullying, 13.4% (n = 267) were pure cybervictims, 0.7% (n = 13) pure cyberbullies, 3.1% cyberbully-victims (n = 62), and 25.6% (n = 510) pure cyberbystanders. In addition, the results reveal that verbal aggression and offensive or insulting messages were the most prevalent forms of aggression in bullying and cyberbullying, respectively. 36.6% of the sample had suffered verbal aggression and 8.4% had received offending or insulting messages. These data show that bullying and cyberbullying are considerably prevalent in this educational stage.
Consequences of Abrading Bed Load on Vertical and Lateral Bedrock Erosion in a Curved Experimental Channel
Authors: Mishra Jagriti , Inoue Takuya , Shimizu Yasuyuki , Sumner Tamaki , Nelson Jonathan M. 
Published: October 2018

AbstractIn this study, we conducted multiple physical experiments to estimate the efficacy and spatial pattern of erosion by abrading sediment moving through a simple U‐shaped channel bend with erodible bed and banks. The experiments showed that in the bend, lateral abrasion followed a monotonically increasing linear relationship with sediment feed rate. However, vertical incision had a more complex relation with the sediment feed rate, with an initial increase in abrasion as the feed rate increased followed by a decrease in abrasion of the bed as cover effects became dominant at higher feed rates. Bank erosion was large in places where the width and the lateral slope of the point bar were relatively large. On the other hand, in places where the width of the point bar was smaller, the bedrock bed was eroded primarily along the boundary of the point bar, resulting in a bedrock bench near the outer bank.
Conditional Causal Mediation Analysis of Factors Associated With Cover Crop Adoption in Iowa, USA
Authors: Lee Danhyang , Arbuckle J. Gordon , Zhu Zhengyuan , Nowatzke Laurie 
Published: October 2018

AbstractThe Iowa Nutrient Reduction Strategy is a statewide effort that aims to encourage voluntary adoption of conservation practices by farmers to reduce the loss of nitrogen and phosphorus that contribute to water quality impairments in the Upper Midwest and drive hypoxic conditions in the Gulf of Mexico. This work is an analysis of the first 2 years (2015–2016) of a 5‐year survey of Iowa farmers. We employ causal mediation analysis to examine the direct and indirect effects of key explanatory variables (e.g., information sources, nutrient management influences, involvement in watershed management activities, and conservation technical assistance) and two causally ordered mediators (farmers' awareness of and attitudes toward the Nutrient Reduction Strategy) on cover crop use. Results showed that participation in watershed activities and receipt of cost share or technical assistance had positive direct effects on cover crop use, while low levels of perceived nutrient loss mitigation self‐efficacy had a negative direct effect. Information and influence of public sector soil and water conservation entities had positive indirect effects on cover crop use through awareness and attitudes, while influence of private sector agribusiness entities had negative indirect effects through those mediators. These results suggest that current strategies such as engaging farmers in watershed management activities and public sector cost share and technical assistance are increasing adoption of cover crops, but the data also point to a need to increase engagement with private sector actors to help them improve their effectiveness as conservation technical assistance providers.
Evolution of 21st Century Sea Level Rise Projections
Authors: Garner Andra J. , Weiss Jeremy L. , Parris Adam , Kopp Robert E. , Horton Radley M. , Overpeck Jonathan T. , Horton Benjamin P. 
Published: October 2018

AbstractThe modern era of scientific global‐mean sea level rise (SLR) projections began in the early 1980s. In subsequent decades, understanding of driving processes has improved, and new methodologies have been developed. Nonetheless, despite more than 70 studies, future SLR remains deeply uncertain. To facilitate understanding of the historical development of SLR projections and contextualize current projections, we have compiled a comprehensive database of 21st century global SLR projections. Although central estimates of 21st century global‐mean SLR have been relatively consistent, the range of projected SLR has varied greatly over time. Among studies providing multiple estimates, the range of upper projections shrank from 1.3–1.8 m during the 1980s to 0.6–0.9 m in 2007, before expanding again to 0.5–2.5 m since 2013. Upper projections of SLR from individual studies are generally higher than upper projections from the Intergovernmental Panel on Climate Change, potentially due to differing percentile bounds or a predisposition of consensus‐based approaches toward relatively conservative outcomes.
Morphodynamic Feedback Loops Control Stable Fringing Flats
Authors: Maan D. C. , van Prooijen B. C. , Zhu Q. , Wang Z. B. 
Published: October 2018

We apply a 2‐D horizontal process‐based model (Delft3D) to study the feedback mechanisms that control the long‐term evolution of a fringing intertidal flat in the Western Scheldt Estuary. The hydrodynamic model is validated using a comparison with measurements on the intertidal flat and the sediment transport module is calibrated against long‐term morphology data. First, the processes that lead to net sediment exchange between channel and flat are studied. Then, long‐term simulations are performed and the dependency of sediment fluxes on the tidal flat bathymetry, and the corresponding morphodynamic feedback mechanisms are explained. In the long run, relatively stable states can be approached, which are shown to be typical for wave‐dominated fringing mudflats. The system behavior can be explained by the typical feedback mechanisms between the intertidal bathymetry and the hydrodynamic forces on the flat. In the subtidal domain, the impact of small (5–10 cm) wind waves increases with a rising elevation due to decreasing water depths. In the intertidal domain, the wave impact increases with increasing cross‐sectional slope due to wave shoaling. These relationships result in negative (stabilizing) morphodynamic feedback loops. The tidal current velocities and tide‐induced bed shear stresses, on the other hand, are largely determined by the typical horizontal geometry. A stabilizing feedback loop fails, so that there is no trend toward an equilibrium state in the absence of wind waves.
Numerical Modeling of Iceberg Capsizing Responsible for Glacial Earthquakes
Authors: Sergeant Amandine , Yastrebov Vladislav A. , Mangeney Anne , Castelnau Olivier , Montagner Jean‐Paul , Stutzmann Eléonore 
Published: October 2018

The capsizing of icebergs calved from marine‐terminating glaciers generate horizontal forces on the glacier front, producing long‐period seismic signals referred to asglacial earthquakes. These forces can be estimated by broadband seismic inversion, but their interpretation in terms of magnitude and waveform variability is not straightforward. We present a numerical model for fluid drag that can be used to study buoyancy‐driven iceberg capsize dynamics and the generated contact forces on a calving face using the finite‐element approach. We investigate the sensitivity of the force to drag effects, iceberg geometry, calving style, and initial buoyancy. We show that there is no simple relationship between force amplitude and iceberg volume, and similar force magnitudes can be reached for different iceberg sizes. The force history and spectral content varies with the iceberg attributes. The iceberg aspect ratio primarily controls the capsize dynamics, the force shape, and force frequency, whereas the iceberg height has a stronger impact on the force magnitude. Iceberg hydrostatic imbalance generates contact forces with specific frequency peaks that explain the variability in glacial earthquake dominant frequency. For similar icebergs, top‐out and bottom‐out events have significantly different capsize dynamics leading to larger top‐out forces especially for thin icebergs. For realistic iceberg dimensions, we find contact‐force magnitudes that range between 5.6 × 1011and 2 × 1014 kg·m, consistent with seismic observations. This study provides a useful framework for interpreting glacial earthquake sources and estimating the ice mass loss from coupled analysis of seismic signals and modeling results.
The Low‐Resolution Version of HadGEM3 GC3.1: Development and Evaluation for Global Climate
Authors: Kuhlbrodt Till , Jones Colin G. , Sellar Alistair , Storkey Dave , Blockley Ed , Stringer Marc , Hill Richard , Graham Tim , Ridley Jeff , Blaker Adam , Calvert Daley , Copsey Dan , Ellis Richard , Hewitt Helene , Hyder Patrick , Ineson Sarah , Mulcahy Jane , Siahaan Antony , Walton Jeremy 
Published: October 2018

AbstractA new climate model, HadGEM3 N96ORCA1, is presented that is part of the GC3.1 configuration of HadGEM3. N96ORCA1 has a horizontal resolution of ~135 km in the atmosphere and 1° in the ocean and requires an order of magnitude less computing power than its medium‐resolution counterpart, N216ORCA025, while retaining a high degree of performance traceability. Scientific performance is compared to both observations and the N216ORCA025 model. N96ORCA1 reproduces observed climate mean and variability almost as well as N216ORCA025. Patterns of biases are similar across the two models. In the northwest Atlantic, N96ORCA1 shows a cold surface bias of up to 6 K, typical of ocean models of this resolution. The strength of the Atlantic meridional overturning circulation (16 to 17 Sv) matches observations. In the Southern Ocean, a warm surface bias (up to 2 K) is smaller than in N216ORCA025 and linked to improved ocean circulation. Model El Niño/Southern Oscillation and Atlantic Multidecadal Variability are close to observations. Both the cold bias in the Northern Hemisphere (N96ORCA1) and the warm bias in the Southern Hemisphere (N216ORCA025) develop in the first few decades of the simulations. As in many comparable climate models, simulated interhemispheric gradients of top‐of‐atmosphere radiation are larger than observations suggest, with contributions from both hemispheres. HadGEM3 GC3.1 N96ORCA1 constitutes the physical core of the UK Earth System Model (UKESM1) and will be used extensively in the Coupled Model Intercomparison Project 6 (CMIP6), both as part of the UK Earth System Model and as a stand‐alone coupled climate model.
Space Weather Modeling Capabilities Assessment: Neutral Density for Orbit Determination at low Earth orbit
Authors: Bruinsma S. , Sutton E. , Solomon S. C. , Fuller‐Rowell T. , Fedrizzi M. 
Published: October 2018

AbstractThe specification and prediction of density changes in the thermosphere is a key challenge for space weather observations and modeling, because it is one result of complex interactions between the Sun and the terrestrial atmosphere and also because it is of operational importance for tracking objects orbiting in near‐Earth space. For low Earth orbit, neutral density variation is the most important uncertainty for propagation and prediction of orbital elements. A recent international conference conducted under the auspices of the National Aeronautics and Space Administration Community Coordinated Modeling Center included a workshop on neutral density modeling, using both empirical and numerical methods, and resulted in organization of an initial effort in model comparison and evaluation. Here we report on the exploitable density data sets available, the selected years and storm events, and the metrics for complete model assessment. Comparisons between five models (three empirical and two numerical) and neutral density data sets that include measurements by the CHAMP, GRACE, and GOCE satellites are presented as examples of the assessment procedure that will be implemented at Community Coordinated Modeling Center. The models in general performed reasonably well, although seasonal errors sometimes are present, and impulsive geomagnetic storm events remain challenging. Numerical models are still catching up to empirical methods on a statistical basis, but hold great potential for describing these short‐term variations.
Wetting Behavior of Tight Rocks: From Core Scale to Pore Scale
Authors: Habibi Ali , Dehghanpour Hassan 
Published: October 2018

AbstractPrevious measurements show mixed‐wet behavior of tight siltstone core plugs, initially saturated with air. However, the same plugs show water‐wet behavior when saturated with oil or water. This study aims at explaining these observations by investigating the effects of mineral heterogeneity and intermolecular forces acting on solid/liquid and liquid/liquid interfaces. First, we conduct pore‐scale visualizations to characterize the minerals surrounding the pores of the tight rock samples. Thin‐section and scanning electron microscopy/energy dispersive X‐ray spectroscopy analyses show the existence of multimineral pores, which can be responsible for the mixed‐wet behavior. Next, we apply the DLVO theory to investigate the intermolecular forces acting on solid/liquid and liquid/liquid interfaces. We use disjoining pressure‐distance profiles and contact angles calculated for different minerals to evaluate the stability of the thin film covering the rock grains and to explain the wettability of the core plugs during spontaneous imbibition tests. The disjoining pressure values calculated for the dry core plugs suggest similar wetting affinities toward oil and water. However, the contact angles calculated for the water‐saturated core plugs suggest the water‐wet behavior, which agrees with the countercurrent imbibition results. Finally, we measure the adhesion forces between the tip of a cantilever and (1) pure quartz slide, (2) pure calcite crystal, and (3) the rock thin section using an atomic force microscope. The values of adhesion forces measured for the thin section composed of multimineral pores are between those measured for pure quartz slide and pure calcite crystal.
Automatic Image‐Based Water Stage Measurement for Long‐Term Observations in Ungauged Catchments
Authors: Eltner Anette , Elias Melanie , Sardemann Hannes , Spieler Diana 
Published: October 2018

AbstractSmall‐scale and headwater catchments are mostly ungauged, even though their observation could help to improve the understanding of hydrological processes. However, it is expensive to build and maintain conventional measurement networks. Thus, the heterogeneous characteristics and behavior of catchments are currently not fully observed. This study introduces a method to capture water stage with a flexible low‐cost camera setup. By considering the temporal signature of the water surface, water lines are automatically retrieved via image processing. The image coordinates are projected into object space to estimate the actual water stage. This requires high‐resolution 3D models of the river bed and bank area, which are calculated in a local coordinate system with structure from motion, employing terrestrial as well as unmanned aerial vehicle imagery. A medium‐ and a small‐scale catchment are investigated to assess the accuracy and reliability of the introduced method. Results reveal that the average deviation between the water stages measured with the camera gauge and a reference gauge are below 6 mm in the medium‐scale catchment. Trends of water stage changes are captured reliably in both catchments. The developed approach uses a low‐cost camera design in combination with image‐based water level measurements and high‐resolution topography from structure from motion. In future, adding tracking algorithms can help to densify existing gauging networks.
Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats
Authors: Wan Yun-Qiang , Feng Jian-Guo , Li Mao , Wang Mao-Zhou , Liu Li , Liu Xueru , Duan Xiao-Xia , Zhang Chun-Xiang , Wang Xiao-Bin 
Published: October 2018

AbstractKetamine has a rapid, obvious, and persistent antidepressant effect, but its underlying molecular mechanisms remain unknown. Recently, microRNAs (miRNAs) have emerged as important modulators of ketamine’s antidepressant effect. We investigated the alteration in miR-29b-3p in the brain of rats subjected to ketamine administration and chronic unpredictable mild stress (CUMS), and a sucrose preference test and forced swimming test were used to evaluate the rats’ depressive-like state. We used recombination adeno-associated virus (rAAV) or lentivirus-expressing miR-29b-3p to observe the change in metabotropic glutamate receptor 4 (GRM4). Cell culture and electrophysiological recordings were used to evaluate the function of miR-29b-3p. Ketamine dramatically increased miR-29b-3p expression in the prefrontal cortex of the normal rats. The dual luciferase reporter test confirmed that GRM4 was the target of miR-29b-3p. The miR-29b-3p levels were downregulated, while the GRM4 levels were upregulated in the prefrontal cortex of the depressive-like rats. The ketamine treatment increased miR-29b-3p expression and decreased GRM4 expression in the prefrontal cortex of the depressive-like rats and primary neurons. By overexpressing and silencing miR-29b-3p, we further validated that miR-29b-3p could negatively regulate GRM4. The silencing of miR-29b-3p suppressed the Ca2+ influx in the prefrontal cortex neurons. The miR-29b-3p overexpression contributed to cell survival, cytodendrite growth, increases in extracellular glutamate concentration, and cell apoptosis inhibition. The overexpression of miR-29b-3p by rAAV resulted in a noticeable relief of the depressive behaviors of the CUMS rats and a lower expression of GRM4. The miR-29b-3p/GRM4 pathway acts as a critical mediator of ketamine’s antidepressant effect in depressive-like rats and could be considered a potential therapeutic target for treating major depression disorder.
Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease
Authors: Kim Hyun-Taek , Yin Wenguang , Jin Young-June , Panza Paolo , Gunawan Felix , Grohmann Beate , Buettner Carmen , Sokol Anna M. , Preussner Jens , Guenther Stefan , Kostin Sawa , Ruppert Clemens , Bhagwat Aditya M. , Ma Xuefei , Graumann Johannes , Looso Mario , Guenther Andreas , Adelstein Robert S. , Offermanns Stefan , Stainier Didier Y. R. 
Published: October 2018

AbstractImpaired alveolar formation and maintenance are features of many pulmonary diseases that are associated with significant morbidity and mortality. In a forward genetic screen for modulators of mouse lung development, we identified the non-muscle myosin II heavy chain gene, Myh10. Myh10 mutant pups exhibit cyanosis and respiratory distress, and die shortly after birth from differentiation defects in alveolar epithelium and mesenchyme. From omics analyses and follow up studies, we find decreased Thrombospondin expression accompanied with increased matrix metalloproteinase activity in both mutant lungs and cultured mutant fibroblasts, as well as disrupted extracellular matrix (ECM) remodeling. Loss of Myh10 specifically in mesenchymal cells results in ECM deposition defects and alveolar simplification. Notably, MYH10 expression is downregulated in the lung of emphysema patients. Altogether, our findings reveal critical roles for Myh10 in alveologenesis at least in part via the regulation of ECM remodeling, which may contribute to the pathogenesis of emphysema.
A computational framework to study sub-cellular RNA localization
Authors: Samacoits Aubin , Chouaib Racha , Safieddine Adham , Traboulsi Abdel-Meneem , Ouyang Wei , Zimmer Christophe , Peter Marion , Bertrand Edouard , Walter Thomas , Mueller Florian 
Published: October 2018

AbstractRNA localization is a crucial process for cellular function and can be quantitatively studied by single molecule FISH (smFISH). Here, we present an integrated analysis framework to analyze sub-cellular RNA localization. Using simulated images, we design and validate a set of features describing different RNA localization patterns including polarized distribution, accumulation in cell extensions or foci, at the cell membrane or nuclear envelope. These features are largely invariant to RNA levels, work in multiple cell lines, and can measure localization strength in perturbation experiments. Most importantly, they allow classification by supervised and unsupervised learning at unprecedented accuracy. We successfully validate our approach on representative experimental data. This analysis reveals a surprisingly high degree of localization heterogeneity at the single cell level, indicating a dynamic and plastic nature of RNA localization.
Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon
Authors: Sahlin Kristoffer , Tomaszkiewicz Marta , Makova Kateryna D. , Medvedev Paul 
Published: October 2018

AbstractA significant portion of genes in vertebrate genomes belongs to multigene families, with each family containing several gene copies whose presence/absence, as well as isoform structure, can be highly variable across individuals. Existing de novo techniques for assaying the sequences of such highly-similar gene families fall short of reconstructing end-to-end transcripts with nucleotide-level precision or assigning alternatively spliced transcripts to their respective gene copies. We present IsoCon, a high-precision method using long PacBio Iso-Seq reads to tackle this challenge. We apply IsoCon to nine Y chromosome ampliconic gene families and show that it outperforms existing methods on both experimental and simulated data. IsoCon has allowed us to detect an unprecedented number of novel isoforms and has opened the door for unraveling the structure of many multigene families and gaining a deeper understanding of genome evolution and human diseases.