bluuebunny/crossref_metadata_2025_split huggingface dataset:
Density difference in pressure‐filtrated wet cakes produced from spontaneous gelling slurries
Authors: Di Zhengxian , Shimai Shunzo , Zhao Jin , Jin Dongliang , Zhang Jian , Zhou Guohong , Liu Juan , Wang Shiwei 
Published: August 2019

AbstractPressure filtration is a key process in ceramic forming; however, the influences of density difference in different parts of a pressure‐filtrated wet cake on subsequent drying and sintering have not yet been explored. In the present work, alumina slurries dispersed by copolymers of isobutylene and maleic anhydride (PIBM) and ammonium salt of polyacrylic acid (PAANH4) were pressure filtrated to examine the impacts of density difference in the as‐prepared wet cakes. In comparison to the wet cake produced from PAANH4, the wet cake with PIBM had much higher bulk density and smaller density difference between its upper and bottom parts (height of ~23 mm). Furthermore, in order to reveal the differences between these two wet cakes, the nature of agglomerates in their slurries was investigated. The slurry with PIBM contained agglomerates with a wider size distribution, bigger average size, and higher sphericity, producing a wet cake with a higher particle packing density and more homogeneous packing structure after pressure filtration. Hence, almost no deformation occurred in a large wet cake (280 mm × 130 mm × 20 mm) with PIBM, whereas that with PAANH4experienced a severe deformation after sintering.
Supraventricular tachycardia with atrial activation earliest at the His bundle region—What is the mechanism?
Authors: Chen Qiufan , Liu Qiang , Jiang Chenyang 
Published: August 2019

AbstractA 70‐year‐old man with recurrent symptomatic supraventricular tachycardia was referred for catheter ablation. Atrial activation was earliest at the His bundle region with HA longer than AH.
A high BNP level predicts an improvement in exercise tolerance after a successful catheter ablation of persistent atrial fibrillation
Authors: Katsumata Yoshinori , Tamura Yuichi , Kimura Takehiro , Kohsaka Shun , Sadahiro Taketaro , Nishiyama Takahiko , Aizawa Yoshiyasu , Azuma Koichiro , Fukuda Keiichi , Takatsuki Seiji 
Published: August 2019

AbstractIntroductionRestoration of sinus rhythm (SR) by catheter ablation (CA) of atrial fibrillation (AF) improves exercise tolerance. However, it is still unclear what characteristics of patients are contributing to an improvement in exercise tolerance after CA of AF without heart failure.Methods and resultsThis study consisted of 51 consecutive patients with persistent or long‐standing persistent AF without heart failure who were restored to SR for over 6 months by a successful CA. Exercise tolerance was evaluated by cardiopulmonary exercise testing before and 3 and 6 months after CA. The clinical characteristics contributing to an improvement in exercise tolerance was elucidated. The peak oxygen uptake (VO2)% significantly increased from 101.4 ± 20.3% to 110.9 ± 19.9% 3 months after the CA (P < .001). The improvement rate in the peak VO2% exhibited a positive correlation to the baseline brain natriuretic peptide (BNP; ρ = 0.39, P < .01), but not to the age, AF duration, left ventricular ejection fraction, or left atrial size. The linear regression analysis revealed that the baseline BNP was an independent predictor of an improvement in the peak VO2% (coefficients = 0.32; 95% conﬁdence interval = 0.08, 0.54; P = .01). The peak VO2% improved significantly in the patients whose baseline BNP level was greater than 100 pg/mL, compared to the others (P < .01). These favorable findings were also observed 6 months after the CA.ConclusionElimination of persistent AF by CA was associated with an improvement in exercise tolerance. This was particularly true in patients with high BNP values at baseline.
Impaired orthostatic blood pressure stabilization and reduced hemoglobin in chronic kidney disease
Authors: Liu Wenjin , Wang Lulu , Huang Xiaoqin , He Weichun , Song Zongwei , Yang Junwei 
Published: August 2019

AbstractImpaired orthostatic blood pressure (BP) stabilization is prevalent in patients with chronic kidney disease (CKD) and is associated with adverse outcomes. We aimed to test the hypothesis that reduced hemoglobin is an important contributor to orthostatic intolerance in CKD in the present study. This study included 262 patients with non‐dialysis‐dependent CKD. Seated and standing BP was measured, and orthostatic BP reduction was calculated for both systolic BP (∆ SBP) and diastolic BP (∆ DBP). The association between orthostatic BP reduction and hemoglobin was determined by multiple linear regression models. We also performed mediation analysis to test to what extent the effect of renal dysfunction on impaired orthostatic BP stabilization can be explained by reduced hemoglobin. The mean age of the patients was 57.7 (±14.5) years, and 61.5% were male. Both ∆ SBP and ∆ DBP correlated negatively with estimated glomerular filtration rate (eGFR). With adjustment for age and sex, hemoglobin level was negatively associated with ∆ SBP (β = −1.4, SE = 0.4, P < .001) and ∆ DBP (β = −0.6, SE = 0.2, P = .009). The associations remained significant with further adjustment for additional covariates. When eGFR was introduced as a covariate, it did not eliminate the significance (both P < .05). The associations remained essentially unchanged in a sensitivity analysis excluding those with concurrent erythropoietin use. Mediation analysis demonstrated that reduced hemoglobin accounted for 35.4% (P = .004) of the effect of eGFR on ∆ SBP and 47.7% (P = .032) on ∆ DBP. Our study suggests that reduced hemoglobin is a potentially important contributor to the development of orthostatic hypotension in CKD.
Dent disease: A window into calcium and phosphate transport
Authors: Anglani Franca , Gianesello Lisa , Beara‐Lasic Lada , Lieske John 
Published: August 2019

AbstractThis review examines calcium and phosphate transport in the kidney through the lens of the rare X‐linked genetic disorder Dent disease. Dent disease type 1 (DD1) is caused by mutations in the CLCN5 gene encoding ClC‐5, a Cl−/H+ antiporter localized to early endosomes of the proximal tubule (PT). Phenotypic features commonly include low molecular weight proteinuria (LMWP), hypercalciuria, focal global sclerosis and chronic kidney disease; calcium nephrolithiasis, nephrocalcinosis and hypophosphatemic rickets are less commonly observed. Although it is not surprising that abnormal endosomal function and recycling in the PT could result in LMWP, it is less clear how ClC‐5 dysfunction disturbs calcium and phosphate metabolism. It is known that the majority of calcium and phosphate transport occurs in PT cells, and PT endocytosis is essential for calcium and phosphorus reabsorption in this nephron segment. Evidence from ClC‐5 KO models suggests that ClC‐5 mediates parathormone endocytosis from tubular fluid. In addition, ClC‐5 dysfunction alters expression of the sodium/proton exchanger NHE3 on the PT apical surface thus altering transcellular sodium movement and hence paracellular calcium reabsorption. A potential role for NHE3 dysfunction in the DD1 phenotype has never been investigated, either in DD models or in patients with DD1, even though patients with DD1 exhibit renal sodium and potassium wasting, especially when exposed to even a low dose of thiazide diuretic. Thus, insights from the rare disease DD1 may inform possible underlying mechanisms for the phenotype of hypercalciuria and idiopathic calcium stones.
Symptom‐specific effects of cognitive‐behavioral therapy, sertraline, and their combination in a large randomized controlled trial of pediatric anxiety disorders
Authors: Cervin Matti , Storch Eric A. , Piacentini John , Birmaher Boris , Compton Scott N. , Albano Anne Marie , Gosch Elizabeth , Walkup John T. , Kendall Philip C. 
Published: August 2019

BackgroundPediatric anxiety disorders are highly prevalent and associated with significant functional disabilities and lifelong morbidity. Cognitive‐behavioral therapy (CBT), sertraline, and their combination are effective treatments, but little is known about how these treatments exert their effects.MethodsUsing network intervention analysis (NIA), we analyzed data from the largest randomized controlled treatment trial of pediatric anxiety disorders (Child/Adolescent Anxiety Multimodal Study, NCT00052078, clinicaltrials.gov/ct2/show/NCT00052078) and outlined the causal symptom domain‐specific effects of CBT, sertraline, and their combination over the course of the 12‐week treatment while taking into account both specificity and overlap between symptom domains.ResultsAll active treatments produced positive effects with the most pronounced and consistent effects emerging in relation to psychological distress, family interference, and avoidance. Psychological distress was consistently the most and physical symptoms the least central symptom domain in the disorder network.ConclusionsAll active treatments showed beneficial effects when compared to placebo, and NIA identified that these effects were exerted similarly across treatments and primarily through a reduction of psychological distress, family interference, and avoidance. CBT and sertraline may have differential mechanisms of action in relation to psychological distress. Given the lack of causal effects on interference outside family and physical symptoms, interventions tailored to target these domains may aid in the building of more effective treatments. Psychological distress and avoidance should remain key treatment focuses because of their central roles in the disorder network. The findings inform and promote developing more effective interventions.
We know DAAs work, so now what? Simplifying models of care to enhance the hepatitis C cascade
Authors: Lazarus J. V. , Pericàs J. M. , Picchio C. , Cernosa J. , Hoekstra M. , Luhmann N. , Maticic M. , Read P. , Robinson E. M. , Dillon J. F. 
Published: August 2019

AbstractGlobally, some 71 million people are chronically infected with hepatitis C virus (HCV). Marginalized populations, particularly people who inject drugs (PWID), have low testing, linkage to care and treatment rates for HCV. Several models of care (MoCs) and service delivery interventions have the potential to improve outcomes across the HCV cascade of care, but much of the relevant research was carried out when interferon‐based treatment was the standard of care. Often it was not practical to scale‐up these earlier models and interventions because the clinical care needs of patients taking interferon‐based regimens imposed too much of a financial and human resource burden on health systems. Despite the adoption of highly effective, all‐oral direct‐acting antiviral (DAA) therapies in recent years, approaches to HCV testing and treatment have evolved slowly and often remain rooted in earlier paradigms. The effectiveness of DAAs allows for simpler approaches and has encouraged countries where the drugs are widely available to set their sights on the ambitious World Health Organization (WHO) HCV elimination targets. Since a large proportion of chronically HCV‐infected people are not currently accessing treatment, there is an urgent need to identify and implement existing simplified MoCs that speak to specific populations’ needs. This article aims to: (i) review the evidence on MoCs for HCV; and (ii) distil the findings into recommendations for how stakeholders can simplify the path taken by chronically HCV‐infected individuals from testing to cure and subsequent care and monitoring.
Linking customer participation to service employees’ work‐to‐family enrichment: The role of job crafting and OBSE
Authors: Loi Raymond , Xu Angela J. , Chow Cheris W.C. , Chan Wilco W.H. 
Published: August 2019

Building on work–home resources model, we develop a conceptual model examining job crafting as the mediator between perceived customer participation and service employees’ work‐to‐family enrichment, and organization‐based self‐esteem (OBSE) as the moderator on this indirect relationship. Using two‐wave survey data collected from hotel service employees, we found that customer participation can enrich employees’ family role through increased cognitive and relational job crafting. In addition, employees’ OBSE accentuates the positive linkage between customer participation and employees’ relational crafting, and subsequently their work‐to‐family enrichment. This study makes important contributions to extant literature on work‐to‐family enrichment and job crafting as well. It also carries important implications for organizations to support employees’ proactive participation in job crafting and enrich employees’ family life.Practitioner points

Organizations should well manage customer participation in order to enhance service employees’ job crafting.

Managers should be aware of how different types of job crafting can enrich their employees’ family domain.

To cultivate effective work‐to‐family enrichment, organizations should develop employees’ self‐worth and sense of competence within the organization.
Using decalcified collagen scaffolds to improve healing after transoral partial glossectomy for squamous cell carcinoma
Authors: Tahim Arpan , Sadiq Zaid 
Published: August 2019

AbstractIntroductionTransoral partial glossectomy procedures for small squamous cell carcinomas of the anterior tongue often leave significant defects which are challenging to reconstruct. Post‐operative scarring leads to adhesions, reduced tongue mobility and limitations of function. We present a series of cases where a decalcified collagen scaffold was successfully used in this challenging reconstructive setting.MethodsAfter standard oncological diagnostic and workup, five patients underwent transoral partial glossectomy procedures. Decalcified collagen scaffolds were used to reconstruct the surgical defect using a standard protocol. Demographic and outcome data were collected retrospectively.ResultsThe median length of post‐operative stay was 5 days. There was no reported post‐operative bleeds or infection. Histological margins were clear. Scaffolds remained in situ at 1 week, and functional recovery was apparent at 6 weeks post‐procedure.DiscussionThese results suggest such scaffolds could be used as an adjunct to help reconstruct the anterior tongue after oncological resection.ConclusionThe study supports a call for further exploration and research into the use of these scaffolds as a potentially beneficial avenue for reconstructing the tongue.
Silicone Additive Manufactured Indices Performed from a Virtual Diagnostic Waxing for Direct Composite Diastema Closure Combined with Resin Infiltration Technique on White Spot Lesions: A Case Report
Authors: Revilla‐León Marta , Fountain Joshua , Piedra‐Cascón Wenceslao , Zandinejad Amirali , Özcan Mutlu 
Published: August 2019

AbstractThe present article describes the resin infiltration technique to address white spots lesions presented on anterior and premolar teeth of a young patient after orthodontic treatment and the digital workflow for planning a diastema closure on the maxillary anterior teeth using facial photographs, an intraoral scanner, a facially driven diagnostic waxing using a dental computer‐aided design (CAD) software, and 3‐piece additive manufactured (AM) clear silicone indices. The virtual design of the silicone indices was completed using an open‐source CAD software and included a flexible clear buccal piece, flexible clear lingual piece, and rigid clear custom tray. The unique 3‐piece index design allows a horizontal path of insertion, controlled uniform thickness of the indices, flexible and rigid material properties combination, accurate translation of the diagnostic waxing into the patient´s mouth, and digital storage of the designs.
Self–other personality agreement and internalizing problems in adolescence
Authors: Luan Ziyan , Bleidorn Wiebke 
Published: August 2019

AbstractObjectiveAchieving a clear self‐view is a lifelong task that is particularly salient during adolescence. Theory and research suggest that close others’ perceptions of individuals’ personality may influence the formation and maintenance of coherent self‐views. The degree to which adolescents develop a stable and coherent self‐view, in turn, may have perennial influences on their mental health and well‐being. This 1‐year longitudinal study investigated the associations between the agreement of self‐ and other‐rated Big Five personality traits and internalizing problems in adolescence.MethodParticipants were 570 Dutch adolescents (51% girls), their mothers, friends, and siblings. We examined the cross‐sectional and longitudinal associations between self–other personality agreement and internalizing problems using polynomial regression analyses and response surface analyses.ResultsResults indicated strong main effects of self‐ and other‐rated personality traits on internalizing problems but provided little evidence for longitudinal associations between self–other personality agreement and internalizing problems.ConclusionOur results cast doubt on the generalizability of the beneficial effects of self–other agreement documented in the adult literature to adolescents but highlight the importance of self‐ and other‐rated personality in youth's mental health development. Discussion focuses on the theoretical implications and recommendations for future investigations of self–other agreement.
Mummified fossil of Keteleeria from the Late Pleistocene of Maoming Basin, South China, and its phytogeographical and paleoecological implications
Authors: Huang Lu‐Liang , Jin Jian‐Hua , Oskolski Alexei A. 
Published: August 2019

AbstractKeteleeria is a small genus of Pinaceae now mainly restricted to eastern Asia. Although this genus has been documented with a wide distribution in the geologic record of Europe, North America, and Asia, its history in low‐latitude areas (including South China) has remained obscure. In this paper, a fossil wood of Keteleeria sp. is described from the Late Pleistocene (29–27 ka BP) of the Maoming Basin, South China. This wood is the most ancient megafossil evidence of Keteleeria within the modern distribution area of this genus. The fossil records of Keteleeria suggests that this thermophyllous genus migrated into South China by the Middle Pleistocene escaping from glacial cooling and became widespread over this region in the Late Pleistocene beginning from the interglacial stage preceding the Last Glacial Maximum. The analysis of growth rings in the fossil wood and its comparison with those of modern Keteleeria davidiana (Bertrand) Beissner indicates that in the Late Pleistocene of Maoming Basin (29–27 ka BP) there was a humid climate with less pronounced seasonality of precipitation than that seen in the subtropical monsoonal climate of modern northeastern Vietnam. Apparently, the Maoming Basin was influenced by interglacial regime with summer–monsoon circulation. The previously proposed method to distinguish between evergreen and deciduous conifers based on growth ring anatomy, is not reliable because of the wide variance and ambiguity in its results.
Improvement of gel properties of mackerel mince by phlorotannin extracts from sporophyll of Undaria pinnatifidai and UVA induced cross‐linking
Authors: Jiang Di , Bai Ying , He Baoyu , Sui Yue , Dong Xiufang , Yu Chenxu , Qi Hang 
Published: August 2019

AbstractThe effects of phlorotannin extracts (PTE) (from sporophyll of Undaria pinnatifida) added at different concentration (0, 1.6, 8, and 40 mg/g protein) with and without ultraviolet A (UVA) irradiation treatment on gel properties of mackerel (Scomberomorus niphonius) mince (MM) were investigated. The results indicated that both the breaking force and water‐holding capacity (WHC) of the MM gel increased with addition of PTE, and the highest breaking force and WHC were observed with 40 mg/g PTE under UVA irradiation. Low‐field nuclear magnetic resonance revealed that free water significantly decreased in this PTE‐MM gel as well. UVA irradiation treatment led to reduction of total sulfhydryls and free amines in the PTE‐MM gel, indicating more cross‐linking between proteins. Electrophoresis results indicated that myosin heavy chains were aggregated in the UVA‐treated PTE‐MM gel. The microstructure of the UVA‐treated PTE‐MM gel showed that protein formed more evenly distributed cross‐linked structures and was more compact than the untreated control gel. As a conclusion, PTE addition with UVA irradiation is shown to improve gelling properties of mackerel mince.
Sexual dimorphism in the size and shape of the raptorial pedipalps of Giant Whip Spiders (Arachnida: Amblypygi)
Authors: McLean C.J. , Garwood R.J. , Brassey C.A. 
Published: August 2019

AbstractSexual dimorphism in the form of elaborate crests, horns and swellings can be a clear indicator of the differing evolutionary pressures to which males and females are subject. However, dimorphism can also be expressed in more subtle shape differences not outwardly obvious to the observer. Whip spiders (Amblypygi) possess a unique pair of spined pedipalps hypothesized to primarily function in prey capture, but also serving multiple other functions. Little is known regarding the intraspecific shape variation of these limbs and its potential causes. Because a role during courtship and male contest has also been hypothesized, sexual selection may contribute to shape differences. As such, we hypothesize that sexual dimorphism will be present in the size and shape of amblypygid pedipalps, with male contest selecting for longer and thicker pedipalps, and larger spines in males. This study aims to test this hypothesis, by quantifying the contribution of ontogeny and sexual dimorphism to shape within the raptorial pedipalps of Damon variegatus. Discriminant function analysis using GMM landmark data reveals statistically significant sexual shape dimorphism in both the tibia and femur of the pedipalp. Contrary to our hypothesis, males display a more gracile pedipalp morphology with reduced spination. Sex differences in the allometric slope and overall size were also found in a number of linear appendicular metrics using Type‐II regression. Males have statistically longer pedipalp tibiae, whip femora, and leg two femora. We propose that males have evolved a longer pedipalps in the context of display contest rather than physical aggression. The elongation of structures used in display‐based contest and courtship found herein further emphasizes the contribution of visual cues to the evolution of morphology more broadly.