bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiology and Perioperative Complications in Patients With Sickle Cell Disease After Orthopaedic Surgery: 26 Years' Experience at a Major Academic Center
Authors: Cusano Joseph , Curry Emily J. , Kingston Kiera A. , Klings Elizabeth , Li Xinning 
Published: March 2019

Introduction:
Surgical management of patients with sickle cell disease (SCD) poses a unique challenge to orthopaedic surgeons due to increased operative and perioperative risk. Studies evaluating perioperative complications among patients with SCD undergoing orthopaedic surgery have been limited. We sought to review the clinical characteristics and perioperative complications in our patients with SCD who required orthopaedic surgery.

Methods:
Our institution has one of the largest sickle cell centers in the Northeastern United States. We performed a retrospective chart review of all patients referred to the Orthopaedic Surgery Department between 1990 and 2016 and analyzed the demographics, comorbidities, surgical intervention, and perioperative complications.

Results:
In total, 96 orthopaedic surgeries were surveyed across 26 years performed at our institution. The majority of the patients with SCD were African American (90.3%) and women (60.4%). The most common surgical intervention was for hip osteonecrosis. Only 11.5% of the patients (11 of 96) experienced a perioperative complication, with the vasoocclusive event being the most common (7 patients; 64%).

Discussion:
These data suggest that orthopaedic surgery for a patient with SCD is safe but does require careful multidisciplinary consultation including hematology and anesthesia to medically optimize the patient before surgical intervention.
Effect of Dentin Desensitizers and Nd:YAG Laser Pre-Treatment on Microshear Bond Strength of Adhesive Resin Cement to Dentin
Authors: SARI Fatih , ŞAHİN Onur , ÖZDEMİR Ali Kemal 
Published: March 2019

Objectives:
The aim of this study was to evaluate how microshear bond strength of different
adhesive resin cements are affected by dentin desensitizers application and
preparation depth. Materials and Methods: One hundred and forty-four maxillary incisors were randomly divided into
two groups according to dentin preparation depth (0.8 and 1 mm) and each group subdivided
into four dentin desensitizers, Nd:YAG (Neodymium-doped Yttrium aluminum Garnet)
laser and control groups. The dentin desensitizers used were Gluma [Glutaraldehyde/
Hydroxyethyl methacrylate (HEMA)], BisBlock (Oxalate) Vivasens-Potassium
Fluoride (KF) and Admira Protect (Ormocer/HEMA), respectively. Three dual cure resin based luting cement
(RelyX ARC; Variolink II and Maxcem Elite) were used to create a 0,7 mm
diameter and 1 mm height cylindirical shape buid-up in tygon tubes (n=10). Micro-shear
bond strength (µSBS) test was performed at a crosshead of speed of 0.5 mm/min
using a Universal testing device. Then tooth surface was investigated by
steromicroscope and scanning electron microscopy (SEM). Data were analyzed using
Kruskal-Wallis, Mann-Whitney U and Chi-Square (X2) tests. (p = 0.05)Results: There
was no statistically difference between the groups at 0.8 mm preparation depth.
At 1 mm preparation dept RelyX ARC + Gluma groups’ mean bond strength value (23.96
± 6.66 MPa) was found statistically lower according to the other groups (p&lt;0.05). RelyX ARC + Laser groups’
mean bond strength value (37.33 ± 7.39 MPa) was found statistically higher
according to the other groups (p&lt;0.05).

Conclusions:
The use of desensitizing agents affected the bond strength of the resin cements
to superficial dentin. Gluma desensitizer affected negatively µSBS of RelyX ARC
resin cement at 1 mm depth. Application of Nd:YAG laser to superficial dentin
showed positive effects to the dentin surface and bond strength. Other
desensitizing agents showed no significant effects on the resin bond strength (p&gt;0.05).
Développement d’un modèle de notation de crédit économétrique général pour des financements de projet
Authors: Rhainds Simon 
Published: March 2019

Dans cet article, nous décrivons le processus de développement d’un modèle de notation de crédit de financement de projet. Tout d’abord, nous présentons chacune des étapes du développement du modèle menant à la sélection des facteurs quantitatifs et macroéconomiques pertinents dans l’établissement des cotes de crédit des financements de projet. Ensuite, des facteurs qualitatifs, dont les poids sont déterminés par jugement d’expert, sont ajoutés au modèle quantitatif afin d’obtenir le modèle final. Plusieurs tests de performance sont effectués sur ce modèle afin de valider le choix des facteurs et le poids de chacun d’eux dans le modèle. L’un de ces tests consiste à comparer la performance du modèle final à celle de plusieurs modèles alternatifs dont les poids des facteurs qualitatifs sont déterminés aléatoirement. Nous constatons que le modèle final surpasse la majorité des modèles alternatifs et surpasse grandement le modèle contenant seulement les facteurs quantitatifs et macroéconomiques.
Expérimentation autour des réfections de rues à Québec : implications citoyennes et nouvelles collaborations municipales
Authors: Bizier Christian , Cloutier Geneviève 
Published: March 2019

À Québec, des comités citoyens réagissent dès la fin des années 1960 aux opérations de rénovation urbaine qui transforment les quartiers populaires de la Basse-Ville. Ces comités s’opposent d’abord aux grands projets d’autoroutes urbaines qui menacent l’accessibilité au logement, et ils visent à protéger l’identité populaire des quartiers. Avec le temps, leurs revendications s’étendent à la réfection des rues et à l’aménagement urbain en général. À partir de 2014, avec un projet pilote, la Ville de Québec expérimente de nouvelles façons d’aborder les réfections de rues, avec l’objectif d’évaluer la pertinence d’une démarche participative et intégrée. Dans cet article, nous défendons l’hypothèse qu’une série de revendications citoyennes, formulées de manière de plus en plus « experte », a pu favoriser l’émergence de cette pratique d’expérimentation municipale.
Patrimoine et participation citoyenne : une relation complexe à revisiter. Le cas du Vieux-Québec
Authors: Berthold Étienne 
Published: March 2019

Jusqu’à présent, les chercheurs se sont peu intéressés aux rapports qui unissent les processus de conservation et de mise en valeur du patrimoine (processus dits de patrimonialisation) et la participation citoyenne. Lorsqu’ils s’y sont intéressés, ils les ont surtout abordés dans la perspective des conflits qui sont susceptibles d’opposer les groupes de pression et les autorités politiques. Sur la base d’une approche qui prend appui sur l’analyse de discours, nous proposons, dans cet article, qu’en matière de patrimonialisation, la participation citoyenne s’inscrit plutôt dans une série de rapports complexes avec l’action publique, marqués tout autant par des partages que par des négociations et des tensions. Pour ce faire, nous prenons appui sur le cas du Vieux-Québec, quartier historique d’une superficie de 1,5 km2qu’un important processus de patrimonialisation déployé à compter de l’après-guerre a érigé en « berceau de l’Amérique française ».
Évolution et défis actuels de la participation publique en aménagement du territoire : l’expérience de l’Office de consultation publique de Montréal (OCPM)
Authors: Ollivier Dominique , Naud Élise , Grenier Guy 
Published: March 2019

Au cours des 15 dernières années, l’Office de consultation publique de Montréal (OCPM) a organisé une vingtaine d’exercices d’amont ou d’aval sur des projets de planification détaillée, notamment des programmes particuliers d’urbanisme (PPU) ou des plans de développement urbain, économique, et social (PDUES). Ce type de consultation a donné lieu à de nombreuses initiatives innovantes visant à mobiliser le public et l’inciter à participer au débat. Cet article fait le point sur les pratiques de l’OCPM en ce qui a trait à l’engagement citoyen dans la planification du territoire et présente les leçons tirées du passé tant en ce qui concerne l’évolution des méthodes de participation citoyenne que les effets de cette participation sur les projets. En cette période d’explosion des méthodes d’engagement numérique, les auteurs désirent aussi faire ressortir des expérimentations, mises de l’avant à l’Office, jugées porteuses pour la participation et évaluer l’évolution de la participation depuis l’avènement de ces méthodes.
Alterations in Center of Pressure During Single-Limb Loading in Individuals with Patellofemoral Pain
Authors: Gwynne Craig R. 
Published: March 2019

Background
Altered foot loading during weightbearing is suggested to play a role in the development of patellofemoral pain (PFP). This study aimed to determine foot-loading characteristics associated with PFP by assessing center of pressure (COP) during single-limb loading in individuals with PFP compared with noninjured controls.

Methods
Thirty recreationally active patients with PFP and 30 noninjured control participants had barefoot plantar pressure assessed during single-limb squats (SLSs) from which COP parameters (COP velocity and COP index) were obtained. Groups were compared using independent t tests.

Results
Individuals with PFP demonstrated a greater COP index (P = .042), indicating a more lateral foot-loading pattern, and exhibited increased overall COP velocity (P = .013) and anteroposterior COP velocity during SLSs compared with control participants (P = .033).

Conclusions
Greater lateral foot loading and increased COP velocity during SLSs demonstrated by individuals with PFP may indicate reduced dynamic balance in this patient group, which may be implicated in the development of PFP.
Identification and characterization of glycosylation sites on Litopenaeus vannamei hemocyanin
Authors: Zhang Zehui , Li Ruiwei , Aweya Jude Juventus , Wang Fan , Zhong Mingqi , Zhang Yueling 
Published: March 2019

The respiratory glycoprotein hemocyanin has been implicated in immune‐related functions. Using lectin blotting, we show that the binding of shrimp (Litopenaeus vannamei) hemocyanin to concanavalin A decreases markedly with O‐glycosidase treatment but not with PNGase F. Twelve O‐glycosylation sites, three on the large hemocyanin subunit and nine on the small hemocyanin subunit (HMCs), were identified by LC‐MS/MS. Importantly, when the glycosylation sites at Thr‐537, Ser‐539, and Thr‐542 on the C terminus of HMCs were replaced with alanine, the resultant mutant hemocyanin had reduced carbohydrate content, coupled with a fourfold reduction in bacterial agglutination and 0.2‐fold reduction in antibacterial activities toward Vibrio parahaemolyticus and Staphylococcus aureus. These results suggest that the glycosylation sites on shrimp hemocyanin are closely related to its immunological functions.
Distributed adaptive control for multiple nonholonomic systems with nonlinearly parameterized uncertainties
Authors: Gu Jianzhong , Li Wuquan , Yang Hongyong 
Published: March 2019

SummaryThis paper investigates the distributed adaptive control problem for multiple nonholonomic systems with nonlinearly parameterized uncertainties. Under the assumption that the graph topology is directed and the leader is globally reachable, distributed adaptive controllers are designed recursively by using backstepping technique and algebra graph theory. It is shown that all the followers' outputs will exponentially converge to the reference output signal while all the signals of the closed‐loop system are bounded. Finally, two simulation examples are given to demonstrate the effectiveness of the control scheme.
Self‐Powered Distributed Water Level Sensors Based on Liquid–Solid Triboelectric Nanogenerators for Ship Draft Detecting
Authors: Zhang Xiangqian , Yu Min , Ma Ziran , Ouyang Han , Zou Yang , Zhang Steven L. , Niu Hukai , Pan Xinxiang , Xu Minyi , Li Zhou , Wang Zhong Lin 
Published: March 2019

AbstractShip draft measurement is of great significance for ensuring navigation safety and facilitating ship control. In this work, a self‐powered water level sensor based on a liquid–solid tubular triboelectric nanogenerator (LST‐TENG) is proposed and analyzed. The LST‐TENG is made of multiple copper electrodes uniformly distributed along a polytetrafluoroethylene (PTFE) tube. When water flows into the PTFE tube, it induces alternating flows of electrons between the main electrode and the distributed bottom electrodes. The obvious peaks in the derivative of open‐circuit voltage with respect to time are found to correspond with the electrode distribution. Then it can be utilized as a robust and sensitive indicator for detecting the water level as the number of obvious peaks in the derivative of open‐circuit voltage is directly related to the water level height. The ship draft is successfully detected using the LST‐TENG with an accuracy of 10 mm. It shows that the water level sensor has stable performance for liquid–solid interface monitoring. Therefore, this LST‐TENG is self‐powered, robust, and accurate for extensive applications in marine industry.
Oxidative N‐Heterocyclic Carbene‐Catalyzed [8+2] Annulation of Tropone and Aldehydes: Synthesis of Cycloheptatriene‐Fused Furanones
Authors: Xia Fei , Gao Zhong‐Hua , Zhang Chun‐Lin , Ye Song 
Published: March 2019

AbstractThe N‐heterocyclic carbene catalyzed [8+2] oxidative annulation of tropone with aldehydes was developed, giving cycloheptatriene‐fused furanones in moderate to good yields. Further reduction of the cycloadducts afforded cycloheptane‐fused furanones and dihydrofuranones in good yields.magnified image
A meta‐analysis of whole genome duplication and the effects on flowering traits in plants
Authors: Porturas Laura D. , Anneberg Thomas J. , Curé Anne E. , Wang Shengpei , Althoff David M. , Segraves Kari A. 
Published: March 2019

Premise of the StudyPolyploidy, or whole genome duplication (WGD), is common in plants despite theory suggesting that polyploid establishment is challenging and polyploids should be evolutionarily transitory. There is renewed interest in understanding the mechanisms that could facilitate polyploid establishment and explain their pervasiveness in nature. In particular, premating isolation from their diploid progenitors is suggested to be a crucial factor. To evaluate how changes in assortative mating occur, we need to understand the phenotypic effects ofWGDon reproductive traits.MethodsWe used literature surveys and a meta‐analysis to assess howWGDaffects floral morphology, flowering phenology, and reproductive output in plants. We focused specifically on comparisons of newly generated polyploids (neopolyploids) and their parents to mitigate potential confounding effects of adaptation and drift that may be present in ancient polyploids.Key ResultsThe results indicated that across a broad representation of angiosperms, floral morphology traits increased in size, reproductive output decreased, and flowering phenology was unaffected byWGD. Additionally, we found that increased trait variation afterWGDwas uncommon for the phenotypic traits examined.ConclusionsOur results suggest that the phenotypic effects on traits important to premating isolation of neopolyploids are small, in general. Changes in flowering phenology, reproductive output, and phenotypic variation resulting fromWGDmay be less critical in facilitating premating isolation and neopolyploid establishment. However, floral traits for which size is an important component of function (e.g., pollen transfer) could be strongly influenced byWGD.
Calochortus gunnisonii furthers evidence for the complex genetic legacy of historical climate change in the southern Rocky Mountains
Authors: Fuller Ryan S. , McGlaughlin Mitchell E. 
Published: March 2019

Premise of the StudyClimate cycles of the Quaternary have impacted plants at a global scale, leaving behind a complex genetic legacy. Species of the northern Rocky Mountains of North America were exposed to more uniform glacial patterns than the central and southern ranges, where synergistic relationships between temperature and precipitation caused differences in the timing and extent of glacier onset. We examined the genetic impacts of climate oscillations on Calochortus gunnisonii (Liliaceae) in the central and southern Rocky Mountains.MethodsPopulations were sampled from disjunct mountain ranges across the basins of Wyoming and northern and central Colorado. Allelic data from nuclear microsatellites and plastid sequences (trnV‐ndhC, petA‐psbJ, and rpl16) were used to examine patterns of genetic structure between and among populations along the southern Rocky Mountain corridor.Key ResultsWe infer considerable population structure concordant with mountain range of origin. Clustering analysis supports separate north and south genetic clusters on either side of major basins in Wyoming, suggesting that populations were maintained in two distinct refugia. Additionally, populations within the Sierra Madre Range of southern Wyoming show localized, divergent genetic signal indicative of a third potential glacial refugium. By contrast, recent genetic admixture is observed in the Laramie, Medicine Bow, and Front ranges, where population expansion from glacial refugia has likely occurred.ConclusionsWe conclude that during climate cycles of the Quaternary, C. gunnisonii experienced periods of population expansion and reduction, habitat fragmentation, isolation in three or more refugia, and admixture mirroring genetic impacts of other southern Rocky Mountains organisms.
Heteranthery in Clarkia: pollen performance of dimorphic anthers contradicts expectations
Authors: Peach Kristen , Mazer Susan J. 
Published: March 2019

Premise of the StudyWild plant species that require the services of pollen‐feeding insects for reliable pollination may evolve features that attract and reward their mutualistic partners. Heterantherous species have been proposed to exhibit a “division of labor” whereby “feeding anthers” (which produce pollen that may be consumed by an insect) are distinguished from “reproductive anthers” (which produce pollen more likely to contribute to reproduction). In some heterantherous species, including Clarkia unguiculata (Onagraceae), these two anther types differ with respect to stamen length, anther size, pollen production, and pollen color.MethodsThe primary goal of this study was to test one component of the “division of labor” hypothesis by comparing the performance of the pollen produced by each type of anther in C. unguiculata. To achieve this goal, under greenhouse conditions, we hand pollinated and assessed pollen performance (using epifluorescence microscopy) within ~228 flowers.Key ResultsThe pollen produced by the two anther types differed significantly with respect to both stigma and style penetration. The inner series of anthers produce pollen with higher performance than the outer series of longer, dark red anthers.ConclusionsThese findings contradict previous descriptions of the genus, reporting that the inner diminutive series of anthers in Clarkia produce “abortive and nonfunctional” pollen. We outline the future research required to demonstrate the ecological function of heteranthery in this iconic wildflower group.
Low water access as a gendered physiological stressor: Blood pressure evidence from Nepal
Authors: Brewis Alexandra , Choudhary Neetu , Wutich Amber 
Published: March 2019

AbstractObjectivesThe study aims to test novel proposed biocultural pathways linking the stressful lived experience of water insecurity to elevated blood pressure, a risk factor for chronic disease. Using the case of Nepal, where women have primary responsibility for managing household water, allows testing for potentially gendered mechanisms that exacerbate negative physiological consequences of water insecurity for women relative to men.MethodsData are from the nationally representative 2016 Nepal Demographic and Health Survey (DHS), N = 8633 women and 6209 men. Multiple regression models tested effects of low household water access on systolic and diastolic blood pressure, as stress biomarkers, comparing women to men. Key covariates included HFIAS food insecurity scores, household wealth class (high, medium, low), and body mass index.ResultsIn this cross‐sectional study, low water access was consistently associated with higher women's systolic and diastolic blood pressure across all wealth levels. The strongest results were for the lowest wealth households, where low water access is concentrated. Higher food insecurity was also associated with higher systolic blood pressure values in women in these households. Men showed no such effects.ConclusionsThis is the first study, to our knowledge, to demonstrate a consistent and direct association between living with water insecurity and elevated blood pressure measures. Findings support the proposition that the stress of living with water insecurity could manifest as chronic disease risk. In the Nepali case, the proposed mechanism appears highly gendered, reflecting the culturally prescribed responsibilities women particularly face for managing household water. Living with food insecurity compounds further the apparent effects.
Actininopathy: A new muscular dystrophy caused by ACTN2 dominant mutations
Authors: Savarese Marco , Palmio Johanna , Poza Juan José , Weinberg Jan , Olive Montse , Cobo Ana Maria , Vihola Anna , Jonson Per Harald , Sarparanta Jaakko , García‐Bragado Federico , Urtizberea Jon Andoni , Hackman Peter , Udd Bjarne 
Published: March 2019

ObjectiveTo clinically and pathologically characterize a cohort of patients presenting with a novel form of distal myopathy and to identify the genetic cause of this new muscular dystrophy.MethodsWe studied 4 families (3 from Spain and 1 from Sweden) suffering from an autosomal dominant distal myopathy. Affected members showed adult onset asymmetric distal muscle weakness with initial involvement of ankle dorsiflexion later progressing also to proximal limb muscles.ResultsIn all 3 Spanish families, we identified a unique missense variant in the ACTN2 gene cosegregating with the disease. The affected members of the Swedish family carry a different ACTN2 missense variant.Interpretation
ACTN2 encodes for alpha actinin2, which is highly expressed in the sarcomeric Z‐disk with a major structural and functional role. Actininopathy is thus a new genetically determined distal myopathy. ANN NEUROL 2019;85:899–906.
Durch sichtbares Licht vermittelte Synthese von β‐Chlorketonen aus Arylcyclopropanen
Authors: Petzold Daniel , Singh Pardeep , Almqvist Fredrik , König Burkhard 
Published: March 2019

AbstractIn diesem Beitrag berichten wir über die durch sichtbares Licht vermittelte Synthese von β‐Chlorketonen aus Arylcyclopropanen, Sauerstoff, Salzsäure und Salpetersäure. Die katalysatorfreie Methode verwendet preisgünstige Standard‐Laborreagenzien und toleriert viele verschiedene funktionelle Gruppen. Darüber hinaus ist die Maßstabsvergrößerung der Reaktion und die späte Funktionalisierung von bioaktiven Verbindungen möglich, wodurch der Cyclopropanring als maskiertes β‐Chlorketon in einer Reaktionssequenz verwendet werden kann. Als Mechanismus schlagen wir eine lichtgetriebene Radikalkette vor, die durch die Reaktion von verdünnter Salzsäure und Salpetersäure zu elementarem Chlor ausgelöst wird. Die mechanistische Hypothese wird durch 18O‐Markierungs‐ und UV/Vis‐Experimente sowie cyclovoltammetrische Messungen und diverse Kontrollreaktionen gestützt.