bluuebunny/crossref_metadata_2025_split huggingface dataset:
La révolution informationnelle
Authors: Victor Raoul 
Published: May 2019

Ce texte de Raoul Victor 1 , adapté d’une présentation faite au forum de la revue Controverses le 13 juin 2013, explicite la nature de la révolution technologique en cours. Faisant écho aux analyses d’André Gorz, il montre que la révolution informationnelle fait germer un nouveau mode de production que le capitalisme tente d’asservir tout en le développant malgré lui. Mais les rapports sociaux post-capitalistes qui s’expriment d’ores et déjà ne sauraient devenir dominants, même à long terme, sans être portés politiquement. Dès lors, une révolution institutionnelle et sociale peut et doit être stratégiquement pensée et agie.
O centenário de Mario Bunge: contextualizando sua obra sobre modelos científicos na filosofia da ciência e como referencial na pesquisa em ensino
Authors: Machado Juliana , Braga Marco 
Published: May 2019

O ano de 2019 marca o centenário de nascimento do físico e filósofo da ciência argentino Mario Augusto Bunge, prolífico autor de uma vastíssima obra que cobre um amplo espectro de interesses. Neste artigo, discutimos sua obra sobre modelos científicos no contexto da filosofia da ciência a partir do século XX. Ao caracterizar a concepção epistemológica do autor, procuramos enfatizar aspectos dessa concepção que se destacam na sua teoria sobre os modelos especificamente quanto à problemática da relação entre o conhecimento e a realidade e argumentamos em favor da fecundidade das ideias bungeanas como referencial para o ensino relativamente a essa problemática. Finalmente, abordamos uma objeção frequentemente feita a esse referencial.
APRESENTAÇÃO DA EDIÇÃO ESPECIAL
Authors: Ipar Carlos Edmundo De Abreu e Lima , Duarte Lauren Da Cunha , Vilasbôas Fernanda Da Silva 
Published: May 2019

apresentação da edição especial 2019

Desde sua fundação em 2006, o Centro Tecnológico de Pedras, Gemas e Joias do Rio Grande do Sul (CT-Pedras) vem atuando no desenvolvimento de atividades que visam contribuir para o avanço científico e tecnológico da cadeia produtiva de gemas e joias, objetivando a apresentação de temas relevantes ao setor e incentivando a discussão desses temas entre a comunidade, empresários e pesquisadores. Com isso, formou-se uma grande rede de instituições e pesquisadores parceiros que abrange todo o Brasil, incluindo a Universidade de Passo Fundo (UPF), entidade mantenedora do CT-Pedras, Universidade Federal do Rio Grande do Sul (UFRGS), principal instituição colaboradora no desenvolvimento dos projetos de pesquisa, além de outras instituições que foram parceiras em diversos projetos desenvolvidos para o setor como a UFSM, UNIVATES, UEMG, UFRJ, SENAI-RS, entre tantos outros.
Dada a intensa gama de ações executadas por toda a rede de parceiros, tendo como agente centralizador o CT-Pedras, o ano de 2019 marca a oitava edição do evento anual “MOSTRA DE PESQUISAS, PRODUTOS E TECNOLOGIAS APLICADAS AO ARRANJO PRODUTIVO DE GEMAS E JOIAS DO RIO GRANDE DO SUL”, tradicionalmente realizado junto a EXPOSOL 2019 – Feira Internacional de Pedras Preciosas, em Soledade/RS.
O ano de 2019 destaca-se pela a conquista de mais uma importante parceria para a divulgação do conhecimento técnico-científico do setor de Gemas e Joias - a Revista de Ciências Exatas Aplicadas e Tecnológicas da Universidade de Passo Fundo (CIATEC-UPF). A publicação dos trabalhos do evento em uma edição especial deste periódico vem para consolidar a qualidade do evento e originalidade das pesquisas, confirmando sua crescente relevância científica para a comunidade acadêmica, assim como a aplicabilidade de seus resultados em benefício da cadeia produtiva de gemas e joias e setores afins.
Os principais temas abordados na VIII edição deste evento e desta edição especial da Revista incluem processos de análise e identificação de gemas, pesquisas sobre irradiação em ametista e quartzo incolor, técnicas de análise via microtomografia de raios-x, perfuração em ágata via jato de água abrasiva, epidemiologia da silicose, estabilização do solo com resíduos do beneficiamento de ágata, padronização e otimização do processo de tingimento a partir da rodamina-B, adsorção da rodamina-B em carvão mineral ativado e tratamento de efluentes oriundo de indústrias de tingimento.
A organização compartilhada desta Mostra com o CT-Pedras, seus mantenedores e apoiadores, como a Universidade de Passo Fundo (UPF), a Universidade Federal do Rio Grande do Sul (UFRGS), o Sindicato das Indústrias (SINDIPEDRAS) e a Prefeitura Municipal de Soledade cada vez mais conduz a resultados de excelência acadêmica e de fundamental relevância profissional e industrial para o setor.

Soledade, abril de 2019

Carlos Edmundo de Abreu e Lima Ipar
Lauren da Cunha Duarte
Fernanda da Silva Vilasbôas
Organizadores
Efeito antimicrobiano e modulador do extrato hidroalcoólico de Genipa americana (Jenipapo)
Authors: Sousa Júnior Dárcio Luiz de , Benjamim Ítalo Mykaell da Silva , Teotônio Luiz Eduardo Oliveira , Gonçalves Filipe Joaquim , Salviano Carla Morgana Tôrres , Leandro Renata Correia , Lopes Maria Janice Pereira , Aquino Pedro Everson Alexandre de , Leite Nadghia Figueiredo 
Published: May 2019

Genipa americana, pertencente à família Rubiaceae, árvore de grande porte que é encontrada em várias áreas do Brasil, popularmente conhecida como Jenipapeiro sendo utilizada para no combate à doenças hepáticas e inflamatórias, além de reduzir o colesterol. Este estudo tem como principal objetivo avaliar a prospecção fitoquímica, antibacteriana e modulatória do extrato hidroalcoólico da casca do caule de Genipa americana frente a cepas de bactérias padrões e multirresistentes. Para a análise da atividade antibacteriana do extrato hidroalcoólico, foi realizado o teste de microdiluição em caldo para determinação da concentração inibitória mínima (CIM), e a modulação de antimicrobianos por meio de gentamicina, amicacina e clindamicina. Os resultados obtidos da CIM pelas bactérias Escherichia coli, Staphylococcus aureus e Pseudomonas aeruginosa foram ≥ 1024µg/mL. Na modulação modificação da concentração de dois antibióticos para cada cepa bacteriana. Assim, é fato rematar que este extrato tem notável atividade moduladora principalmente quando testados contra bactérias de interesse clínico como a P. aeruginosa, bactérias oportunista, ressaltando que deve-se ser realizados mais estudo sobre o potencial desta espécie, que possui compostos fitoquímicos importantes capazes de reduzir a resistência a antimicrobianos.
Relationship among HbA1c and Some Markers of Endothelial Damage in Type 2 Diabetes Mellitus
Authors: Ositadinma Ifeanyichukwu Martin , Martina Ngwu Amauche , Chekwube Eluke Blessing 
Published: May 2019

Background: A number of processes regulating the thrombolytic balance are impaired in diabetic patients as a result of dysfunction of endothelial cells leading to a hypercoagulative state. Von Willebrand factor (VWF) is an important marker of endothelial dysfunction. Plasminogen activator inhibitor-1 antigen (PAI-1-Ag), the major physiological inhibitor of tissue plasminogen activator (tPA), is mainly produced by endothelium. The aim of this study is to measure plasma levels of von Willebrand factor, Plasminogen activator inhibitor-1 antigen in type 2 diabetes mellitus patients and to correlate with glycated haemoglobin (HbA1c).
Study Design: This prospective cohort study was conducted on 30 diagnosed type 2 DM patients who were about to start treatment.
Place and Duration of Study: Medical outpatient (MOP) clinic of Enugu State University of Science and Technology Teaching Hospital (ESUTTH), between January and December 2016.
Methodology: We included 30 patients (13 men, 17 women; age range 40-80 years) with type 2 diabetes mellitus. Blood samples were drawn from the patients before they commenced treatment, six months into the treatment and at twelve months of the treatment. Blood samples were also drawn from 25 age matched non diabetic patients. Plasma von Willebrand factor and Plasminogen activator inhibitor-1 antigen levels were determined by Enzyme linked immunosorbent assay. Glycated haemoglobin (HbA1c) and fasting blood sugar (FBS) levels were also evaluated along with them.
Results: This study was conducted on 30 type 2 DM patients consisting of 13 males and 17 females. At treatment naïve, mean levels of vWF were significantly increased (45.48 +/- 6.46) in male type 2 Diabetic patients compared to the control (20.45 +/- 0.26). Six months into treatment mean levels of vWF were significantly increased (48.18 +/- 4.99) in female type 2 Diabetic patients compared to the control (37.64 +/- 7.93). The plasma levels of vWF were significantly and positively correlated with HbA1c at six months into treatment in male type 2 DM patients. The plasma levels of vWF were also significantly and positively correlated with PAI-1 at six and twelve months into treatment in both genders.
Conclusion: There was strong significant positive correlation between plasma levels of vWF and PAI-1 in type 2 diabetes mellitus patients.
Assessment of Mitigation Measures in Preventing Bacterial Infections in Selected Public Health Centres in Akure, Ondo State
Authors: Omoya F. O. , Momoh A. O. , Ajayi K. O. 
Published: May 2019

Introduction: Hospital acquired infection (or nosocomial) is an infection whose development is favored by hospital environment. They are usually acquired by either a patient during a hospital visit (or when hospitalized), hospital staff or patients’ relatives that visit when the patient is on admission in the hospital. Nosocomial infections can cause severe pneumonia and infection of the urinary tract, wounds, blood stream and other parts of the body. Nosocomial infections are commonly encountered in Africa and in Nigeria in particular. Factors such as hospital hygiene / cleanliness, personal hygiene of patients, overcrowding hospital wards and illiteracy increases the risk of nosocomial infection.
Methods: The assessment of mitigation measures put in place to reduce bacteria present in surfaces of facilities (pillow, bed sheets, door handles, toilet seats and the floor) in wards of selected basic health centres (Arakale, Aule, Ayedun, Isolo, Oba-Ile and Orita-Obele) in Akure was evaluated using both questionnaire and on-sight assessment techniques.
Results: The results showed that there was a direct relationship between the hand washing or sanitizer used and the bacterial load present in the various surfaces examined.
Conclusion: Therefore, adequate ward hygiene in these health centres is necessary to reduce the risk of nosocomial infections for both patients and visitors.
The cognitive load of narrative lies
Authors: Bird Lisa , Gretton Matthew , Cockerell Robert , Heathcote Andrew 
Published: May 2019

SummaryLying is assumed to increase cognitive load, and it has been shown to slow response times to simple questions. We employed a dual‐task methodology, the detection response task (DRT), to assess cognitive load in telling narrative lies in a live, open‐question interview. The DRT requires participants to press a button in response to a tactile stimulus every 3–5 s while performing a primary task, in this case, recounting either truthful or deceitful narratives. We found weak support for slowing in the time to initiate a narrative response when lying. In contrast, we found strong support for an increase in cognitive load when producing a narrative lie, as measured by both slowed DRT responses and increased response omissions, although this effect decreased with time on task. We advocate dual‐task methodologies such as the DRT for increasing understanding of the assumptions made by theories of deception and for refining lie detection techniques.
Versatile and Enantioselective Total Synthesis of Naturally Active Gnetulin
Authors: Shang Changhui , Kang Yulong , Yang Qingyun , Zhu Qibin , Yao Chunsuo 
Published: May 2019

AbstractA versatile and efficient enantioselective total synthesis of natural isorhapontigenin dimers (−)‐gnetulin, (+)‐gnetulin, and (±)‐gentulin was proposed. By using this method, we were able to synthesize the dimers from commercial available achiral materials in 13 steps, and achieve a 7%–9% overall yield with >98% enantiomeric excess. The key features of the method include the stereocontrolled enantioselective conjugate reduction of 3‐arylindenone catalyzed by methyloxazaborolidine (Me‐CBS) and the α‐arylation of 3‐aryl‐1‐indanones. Benzylic sulfide was accessed in excellent yield through the InCl3‐catalyzed thio‐etherification reaction between 2,3‐diarylindanol and bezylic thiol. The method is practical and might thus be useful in the enantioselective synthesis of the optical antipodes of natural indane derivatives with or without methoxy groups at aromatic rings.magnified image
Acromesomelic dysplasia Maroteaux‐type in patients from Vietnam
Authors: Tran Thinh Huy , Cao My Ha , Luong Long Hoang , Le Phuong Thi , Vu Dung Chi , Ta Thanh Dat , Bui The‐Hung , Nguyen Duc Hinh , Van Ta Thanh , Tran Van Khanh 
Published: May 2019

AbstractAcromesomelic dysplasias are rare skeletal disorders leading to severe short stature and abnormal skeletal morphology. Acromesomelic dysplasia Maroteaux‐type is caused by homozygous or compound heterozygous pathogenic variants in NPR2 that encodes for natriuretic peptide receptor B. Here, we reported the first AMDM case in South East Asia and identified a novel pathogenic variant in NPR2 (c. 152T>C, p. (Leu51Pro)). Further analyses reveal the parents and two other family members were heterozygous for the variant. The clinical report highlights the importance of molecular genetic testing in diagnosing rare hereditable disease affecting skeletal abnormalities.
Properties of a novel inherently flame‐retardant rigid polyurethane foam composite bearing imide and oxazolidinone
Authors: Jia Daikun , Hu Jin , He Jiyu , Yang Rongjie 
Published: May 2019

ABSTRACTA novel inherently flame‐retardant rigid polyurethane (PU) foam with imide and oxazolidinone was prepared by using 3,3′,4,4′‐biphenyltetracarboxylic dianhydride (PTDA) and 9,10‐dihydro‐9‐oxa‐(10‐glycidoxypropylene)‐10‐phosphap‐henanthrene‐10‐oxide (e‐DOPO) as reactive flame retardants. The physical and mechanical properties of the prepared PU foams were investigated. The compressive strength was improved to 0.22 MPa, the thermal conductivity decreased, and the density hardly changed. Thermogravimetric (TG) analysis and TG analysis coupled with Fourier transform infrared spectroscopy indicated that the PTDA and e‐DOPO showed a small improvement in thermal properties. The fire behaviors were evaluated based on the limited oxygen index (LOI), cone‐calorimetry experiment, and smoke‐density test. The LOI of the PU foam with PTDA and e‐DOPO reached 22.4%. The peak of heat release rate and total heat release decreased to 227.50 kW m−2 and 11.27 MJ m−2 from 281.28 kW m−2 and 14.05 MJ m−2, respectively. The morphologies of the PU foam and residues after the cone‐calorimetry test were characterized by scanning electron microscopy. X‐ray photoelectron spectroscopy analysis indicated that PTDA and e‐DOPO lead to an increase in graphite in the residue and the formation of a better barrier to prevent burning by the condensed‐phase mechanism. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47943.
Selective Synthesis of Secondary and Tertiary Amines by Reductive N‐Alkylation of Nitriles and N‐Alkylation of Amines and Ammonium Formate Catalyzed by Ruthenium Complex
Authors: Alshakova Iryna D. , Nikonov Georgii I. 
Published: May 2019

AbstractA new ruthenium catalytic system for the syntheses of secondary and tertiary amines via reductive N‐alkylation of nitriles and N‐alkylation of primary amines is proposed. Isomeric complexes 8 catalyze transfer hydrogenation and N‐alkylation of nitriles in ethanol to give secondary amines. Unsymmetrical secondary amines can be produced by N‐alkylation of primary amines with alcohols via the borrowing hydrogen methodology. Aliphatic amines were obtained with excellent yields, while only moderate conversions were observed for anilines. Based on kinetic and mechanistic studies, it is suggested that the rate determining step is the hydrogenation of intermediate imine to amine. Finally, ammonium formate was applied as the amination reagent for alcohols in the presence of ruthenium catalyst 8. Secondary amines were obtained from primary alcohols within 24 hours at 100 °C, and tertiary amines can be produced after prolonged heating. Secondary alcohols can only be converted to secondary amines with moderate yield. Based on mechanistic studies, the process is suggested to proceed through an ammonium alkoxy carbonate intermediate, where carbonate acts as an efficient leaving group.
Selective Hydrogenation of CO2 Dictated by Isomers in Au28(SR)20 Nanoclusters: Which One is Better?
Authors: Xu Jiayu , Chen Mingyang , Zhu Yan 
Published: May 2019

AbstractIt is a challenge to make clear how isomerism in a heterogeneous catalyst induces distinct differences in catalytic properties, as attainment of the structural isomerism in a conventional catalyst is difficult. By successfully identifying the isomerism in the atomically precise Au nanoclusters, an exciting opportunity for unravelling catalysis of isomeric catalysts is opened up. Herein, we report that the isomerism in the Au28(SR)20 nanoclusters with different surface atom arrangements can indeed render different catalytic behaviors in the selective hydrogenation of CO2. We anticipate that our studies will serve as a starting point for fundamental investigations about how to control the catalytic activity and selectivity by the isomerism‐induced catalysis.
5 nm Ordered Structures Self‐Assembled by C2‐Symmetric Hybrids with Polyhedral Oligomeric Silsesquioxane and Hexa‐peri‐Hexabenzocoronene.
Authors: Zhang Wei , Pan Hongbing , Lyu Xiaolin , Gu Kehua , Xiao Anqi , Shen Zhihao , Fan Xing‐he 
Published: May 2019

AbstractHybrids consisting of polyhedral oligomeric silsesquioxane (POSS) and hexa‐peri‐hexabenzocoronene (HBC) with a dumbbell topology and C2 symmetry were designed and synthesized. They self‐assemble into 5 nm ordered structures. In particular, the increased steric effect with increasing POSS units stabilizes a square columnar phase (Colsqu) which is important in nanotemplating. These hybrids containing discotic liquid crystal HBC and POSS units have an excellent etching contrast and present an approach to obtain 5 nm nanopatterns.
One‐Pot Synthesis of Sulfur and Nitrogen Co‐Functionalized Graphene Material using Deep Eutectic Solvents for Supercapacitors
Authors: Wadekar Pravin H. , Khose Rahul V. , Pethsangave Dattatray A. , Some Surajit 
Published: May 2019

AbstractA green approach to the synthesis of sulfur and nitrogen co‐functionalized reduced graphene oxide (SN‐rGO) is presented; it involves the reduction of graphene oxide (GO) using a deep eutectic solvent (DES) as chemical reducing agent and dopant. For the first time, a DES of choline chloride and sodium sulfide comprising cheap and safe components is introduced, and is both highly effective and reusable as a reducing agent for the production of SN‐rGO. The DES is utilized as a solvent as well as reducing agent and dopant to generate SN‐rGO. This DES is highly efficient in removing oxygen functionalities from GO and for subsequent sulfur and nitrogen functionalization for high energy‐storage efficiency. The reduction ability of this DES is confirmed with five consecutive cycles, which adds to its sustainability and recyclability in the development of energy‐storage devices. SN‐rGO exhibits a high specific capacitance of 509 F g−1at 1 A g−1, which corresponds to high energy and power densities of 57.3 Wh kg−1and 1804.7 W kg−1, respectively. This simple and green method for direct reduction of GO with sulfur and nitrogen functionalization on the graphene surface can provide cost‐effective bulk production of a nanocarbon template for energy storage applications.
Selecting costimulatory domains for chimeric antigen receptors: functional and clinical considerations
Authors: Weinkove Robert , George Philip , Dasyam Nathaniel , McLellan Alexander D 
Published: May 2019

AbstractCostimulatory signals are required to achieve robust chimeric antigen receptor (CAR) T cell expansion, function, persistence and antitumor activity. These can be provided by incorporating intracellular signalling domains from one or more T cell costimulatory molecules, such as CD28 or 4‐1BB, into the CAR. The selection and positioning of costimulatory domains within a CAR construct influence CAR T cell function and fate, and clinical experience of autologous anti‐CD19 CAR T cell therapies suggests that costimulatory domains have differential impacts on CAR T cell kinetics, cytotoxic function and potentially safety profile. The clinical impacts of combining costimulatory domains and of alternative costimulatory domains are not yet clearly established, and may be construct‐ and disease‐specific. The aim of this review is to summarise the function and effect of established and emerging costimulatory domains and their combinations within CAR T cells.
Improved detection of influenza A virus from blue‐winged teals by sequencing directly from swab material
Authors: Ferreri Lucas M. , Ortiz Lucia , Geiger Ginger , Barriga Gonzalo P. , Poulson Rebecca , Gonzalez‐Reiche Ana Silvia , Crum Jo Anne , Stallknecht David , Moran David , Cordon‐Rosales Celia , Rajao Daniela , Perez Daniel R. 
Published: May 2019

AbstractThe greatest diversity of influenza A virus (IAV) is found in wild aquatic birds of the orders Anseriformes and Charadriiformes. In these birds, IAV replication occurs mostly in the intestinal tract. Fecal, cloacal, and/or tracheal swabs are typically collected and tested by real‐time RT‐PCR (rRT‐PCR) and/or by virus isolation in embryonated chicken eggs in order to determine the presence of IAV. Virus isolation may impose bottlenecks that select variant populations that are different from those circulating in nature, and such bottlenecks may result in artifactual representation of subtype diversity and/or underrepresented mixed infections. The advent of next‐generation sequencing (NGS) technologies provides an opportunity to explore to what extent IAV subtype diversity is affected by virus isolation in eggs. In the present work, we evaluated the advantage of sequencing by NGS directly from swab material of IAV rRT‐PCR‐positive swabs collected during the 2013–14 surveillance season in Guatemala and compared to results from NGS after virus isolation. The results highlight the benefit of sequencing IAV genomes directly from swabs to better understand subtype diversity and detection of alternative amino acid motifs that could otherwise escape detection using traditional methods of virus isolation. In addition, NGS sequencing data from swabs revealed reduced presence of defective interfering particles compared to virus isolates. We propose an alternative workflow in which original swab samples positive for IAV by rRT‐PCR are first subjected to NGS before attempting viral isolation. This approach should speed the processing of samples and better capture natural IAV diversity.OPEN RESEARCH BADGES

This article has earned an Open Data Badge for making publicly available the digitally‐shareable data necessary to reproduce the reported results. The data is available at https://doi.org/10.5061/dryad.3h2n106.