bluuebunny/crossref_metadata_2025_split huggingface dataset:
Birlikte Yaşama Tecrübesine ve Ortak Yaşam Alanına İşaret Eden Kavramsal Bir Çalışma: Ebrulî Kültür (Mardin Örneği)
Authors: Yeşilmen Halit 
Published: May 2019

Bir toplumdaki etnik ve dini çeşitliliği ifade etmek
için genellikle çokkültürlülük kavramı kullanılmaktadır. Bu kavram, iç dinamikleri tanımlamada yetersizdir. Bu nedenle Mardin
örneğinde yeni bir kavrama odaklanılmıştır: Ebrulî kültür. Kavramsallaştırmada
“değer” yaklaşımı esas alınmıştır. Makalede
ebrulî kültür kavramını açıklamak ve bundan hareketle farklı etno-dini
grupların yüzyıllara dayanan etkileşim dinamiğine işaret etmek amaçlanmıştır. Bu amaçla Batı ülkeleri için kullanılması uygun olan mozaik,
gökkuşağı ve melez gibi kavramlar sorgulanmıştır. Bu kavramlar, Türkiye’deki sosyo-kültürel
dinamikleri tanımlamada yetersiz olarak değerlendirilmiştir. Ayrıca
Türkiye’deki farklı etno-dini gruplar arası etkileşimin “değer” üzerinden inşa
edildiği vurgulanmıştır. Fakat bu etkileşim biçimi, uzun tarihi geçmişe
dayanmasına rağmen günümüzde değişmektedir. Bununla
birlikte, sosyo-kültürel alana dönük iyileştirmelerin “değer” merkezli
yaklaşımlarla ele alınması gerektiği sonucuna ulaşılmıştır.
Desmoplastic Fibroma: A Rare Pathological Midshaft Femoral Fracture Treated With Resection, Acute Shortening, and Re-lengthening
Authors: Stevens Jarrad , Moin Sarah , Salter Donald , Patton James T. 
Published: May 2019

Case:
We report a rare case of desmoplastic fibroma (DF) of the midshaft femur presenting as a pathological fracture. This rare benign bone tumor was treated with an acute en bloc excision and femoral shortening over an intramedullary nail. Once union of the acute shortening had been achieved, further surgery was undertaken to lengthen the femur with the use of Intramedullary Skeletal Kinetic Distractors. At 3 years after fracture, our patient had achieved equal leg lengths, had normal knee function, and was disease free.

Conclusions:
DF resulting in pathological fracture of the midshaft femur is extremely rare and has not been reported to occur in the femoral diaphysis. This location is important as preservation of the joint above and below is preferable and en bloc excision is recommended. Restoration of bone stock after en bloc excision is difficult and recurrence needs to be monitored.
Bilateral Extensor Mechanism Allograft Reconstruction for Chronic Spontaneous Rupture
Authors: Lamberti Alfredo , Loconte Francesco , Spinarelli Antonio , Baldini Andrea 
Published: May 2019

Case:
A 51-year-old woman, affected by end-stage renal disease, presented with 16-month-old ruptures of the right patellar tendon and the left quadriceps tendon. Since she had been nonambulatory for more than a year, the authors decided to perform a bilateral one-staged reconstruction with an Achilles tendon allograft on the right side and a full extensor mechanism allograft on the left side, achieving excellent clinical and functional results at 57 months’ follow-up.

Conclusions:
Bilateral spontaneous rupture of the extensor mechanism of the knee is a rare but dramatic occurrence. Allograft can be considered as a treatment option in case of chronic lesion or delayed reconstruction, with satisfactory midterm outcomes.
Evaluación formativa y compartida en 1º de Educación Primaria: una experiencia de éxito en el área de matemáticas
Authors: García-Herranz Sofía , López-Pastor Víctor M. 
Published: May 2019

A lo largo del siguiente trabajo mostramos una experiencia de evaluación formativa y compartida puesta en práctica en la asignatura de matemáticas en el 1º curso de Educación Primaria. Exponemos los resultados obtenidos al aplicar una nueva forma de evaluar, entendiendo la evaluación como una herramienta que permite generar aprendizaje y donde los alumnos cobran un papel destacado. En el estudio se muestran las principales actividades de aprendizaje puestas en práctica durante el curso escolar y los instrumentos empleados tanto por parte de los alumnos en su proceso de evaluación (caras, Óscar, estrellas, etc.) como por el docente (escalas verbales, filmaciones, diario, etc.); además de dar a conocer las principales ventajas e inconvenientes encontradas tras la aplicación de la experiencia. Finalmente, los resultados de la investigación muestran como a través de este sistema de evaluación se produce una mejora significativa en el nivel general de la clase, una mayor motivación, autonomía y compromiso hacia la tarea por parte de los alumnos, además de fortalecerse otros ámbitos del desarrollo; siendo clave la participación de la familia en todo el proceso.
Biochemical Effects of Piper Guineense (African Black Pepper) in Female Diabetics: Opportunities for Diabetes Treatment
Authors: Amadi Gordon , Iwuji Samuel C. , Azeez Taofik O. , Nwaokoro Chidozie J. , Wodu Chioma O. 
Published: May 2019

Objectives: To investigate the biochemical effects of oral doses of Piper guineense (P. guineense) leaf extract on female diabetics using experimental animals.
Methods: The animals, albino wistar rats, were divided into six groups (n=7). Animals in group 1 received water and feed only. Animals in groups 2 to 6 were induced with diabetes using alloxan. Methanolic leave extracts of P. Guineense were administered to groups 2 to 4 in 40 mg/kg, 80 mg/kg and 100 mg/kg body weights representing low, medium and high doses respectively. Group 5 animals were treated with 10 mg/kg body weight of Glibenclamide (Antidiabetic drug) and group 6 animals were left untreated. All treatments were carried out orally and lasted for a period of 14 days. At the end of the 14 days, the animals were humanely sacrificed through cardiac puncture and the blood samples collected for the analyses of some liver and kidney function parameters using assay kits.
Results: The results showed that the oral doses of methanolic leave extract of P. guineense had no negative alterations on the biochemical parameters analyzed namely, 1) Lipid profile (Triglyceride, Low Density Lipoprotein, Total Cholesterol and High Density Lipoprotein levels), 2) electrolytes profile (Sodium, Potassium, Chloride, Bicarbonate, 3) Urea) and 4) Creatinine levels. Furthermore, there was a significant reduction in the urea levels of treated animals and marked but insignificant reduction in the total cholesterol level and increase in High Density Lipoprotein at P<0.05.
Conclusion and Implication for Translation: The reported antidiabetic P. guineense leaf extract caused no adverse biochemical changes in female diabetic rats. This implied that the extract may not distort the lipid and electrolyte profiles of female diabetics and could be pharmacologically safe in the management of female diabetics. It further implied that the Piper, Uziza, commonly taken after childbirth by nursing mothers in some tropical countries may maintain the lipid and electrolyte balance and consequently, prevent hypercholesterolemia and hypertension.
Keywords: • Diabetes • Piper guineense • Lipids • Electrolytes • Methanolic extracts • Black pepper

© 2019 Gordon et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Stochastic Oilfield Optimization Under Uncertain Future Development Plans
Authors: Jahandideh Atefeh , Jafarpour Behnam 
Published: May 2019

Summary
Reservoir simulation is a valuable tool for performance prediction, production optimization, and field-development decision making. In recent years, significant progress has been made in developing automated workflows for optimization of production and field development by combining reservoir simulation with numerical optimization schemes. Although optimization under geologic uncertainty has received considerable attention, the uncertainty associated with future development activities has not yet been considered in field-development optimization. In practice, reservoirs undergo extensive development activities throughout their life cycle. Disregarding the possibility of future developments can lead to field-performance predictions and optimization results that might be far from optimal. This paper presents a stochastic optimization formulation to account for the uncertainty in future development activities while optimizing current decision variables (e.g., well controls and locations). A motivating example is presented first to demonstrate the significance of including the uncertainty in future drilling plans in oilfield-development optimization. Because future decisions might not be implemented as planned, a stochastic optimization framework is developed to incorporate future drilling activities as uncertain (random) variables. A multistage stochastic programming framework is introduced, in which the decision maker selects an optimal strategy for the current stage decisions while accounting for the uncertainty in future development activities. For optimization, a sequential approach is adopted whereby well locations and controls are repeatedly optimized until improvements in the objective function fall below a threshold. Case studies are presented to demonstrate the advantages of treating future field-development activities as uncertain events in the optimization of current decision variables. In developing real fields, where various unpredictable external factors can cast uncertainty regarding future drilling activities, the proposed approach provides solutions that are more robust and can hedge against changes/uncertainty in future development plans better than conventional workflows.
A Novel Approach for Estimating Formation Permeability and Revisiting After-Closure Analysis of Diagnostic Fracture-Injection Tests
Authors: Wang HanYi , Sharma Mukul M. 
Published: May 2019

Summary
Estimating reservoir-flow capacity is crucial for production estimation, hydraulic-fracturing design, and field development. Laboratory experiments can be used to measure the permeability of rock samples, but the results might not be representative at a field scale because of reservoir heterogeneity and pre-existing natural-fracture systems. Diagnostic fracture-injection tests (DFITs) have now become standard practice to estimate formation pore pressure and formation permeability. However, in low-permeability reservoirs, after-closure radial flow is often absent and this can result in significant uncertainties in interpreting DFIT data. In addition, the established methods for analyzing DFIT data make two oversimplified assumptions: Carter leakoff and constant fracture compliance (or stiffness) during fracture closure. However, both assumptions are violated during fracture closure; therefore, G-function-based models and subsequent related work can lead to an incorrect interpretation and are not capable of consistently fitting both before- and after-closure data coherently. Moreover, current after-closure analysis relies on classic well-test solutions with a constant injection rate. In reality, a “constant injection rate” does not equal “constant leakoff rate into the formation,” because more than 90% of the injected fluid stays inside the fracture at the end of pumping instead of leaking into the formation. The variable leakoff rate clearly violates the constant-rate boundary condition used in existing well-test solutions.
In this study, we extend our previous work and derive time-convolution solutions to pressure-transient behavior of a closing fracture with infinite and finite fracture conductivity. We show that the G-function and the square-root-of-time models are only special cases of our general solutions. In addition, we found that after-closure linear-flow and bilinear-flow analysis can be used to infer pore pressure reliably but fail to estimate other parameters correctly. Most importantly, we present a new approach to history match the entire duration of DFIT data to estimate formation-flow capacity, even without knowing closure stress and the roughness properties of the fracture surface. Our approach adds significant value to DFIT interpretation and uncertainty analysis, especially in unconventional reservoirs where the absence of after-closure radial flow is the norm. Two representative field cases are also presented and discussed.
Optical coherence tomography angiography of myopic choroidal neovascularization treated by anti-VEGF therapy
Authors: Mao Jianbo , Shao Yirun , Liu Chenyi , Zhang Caiyun , Chen Yiqi , Zhang Yun , Xu Zhaokai , Shen Lijun 
Published: May 2019

Abstract
Background: To analyze the efficiency of anti-vascular endothelial growth factor (anti-VEGF) therapy for myopic choroidal neovascularization (CNV) by optical coherence tomography angiography (OCTA) and to determine the reduction ratio of CNV lesions after anti-VEGF therapy.
Methods: A total of 41 patients (41 eyes) with myopic CNV who were treated with anti-VEGF were included in the study. The best corrected visual acuity (BCVA), superficial vessel density, deep vessel density, the area of foveal avascular zone (FAZ), central macular thickness (CMT) and the area and the flow area of CNV lesion at baseline and at the follow-up after 1, 2, 3 and 6 months were measured.
Results: After treatment, BCVA improved (F=6.848, P<0.05), while the CMT (F=2.489, P<0.05), the area (F=3.125, P<0.05) and the flow area (F=3.558, P<0.05) of CNV lesion reduced. On the other hand, superficial vessel density, deep vessel density and the area of FAZ had no change. The mean reduction ratio of lesions was 50.32% (7.07% to 100%). Only in two cases, 100% lesion regression was observed (4.88%). There was a negative correlation between the CNV lesion area and reduction ratio (r=–0.380，P=0.042) and the flow lesion area and reduction ratio (r=–0.402, P=0.030).
Conclusions: Anti-VEGF therapy is efficient for myopic CNV without affecting superficial vessel density and deep vessel density of retina, but it is unable to completely eliminate CNV lesions in most cases. The mean reduction ratio is 50.32%, and the bigger myopic CNV lesions have a lower reduction ratio.
Assessment of morphological and functional alterations in patients with early stage of non-proliferative diabetic retinopathy by optical coherence tomography angiography and microperimetry
Authors: Zhu Dandan , Liu Xun 
Published: May 2019

Abstract
Background

To analyze the optical coherence tomography angiography(OCTA) and microperimetry features in diabetic patients without diabetic retinopathy(NDR group) and patients with early stage of non-proliferative diabetic retinopathy(NPDR group).

Methods

This was a cross-sectional study including 24 eyes of the NDR group, 24 eyes of the NPDR group, and 24 eyes of healthy volunteers(control group). OCTA was used to measure foveal avascular zone(FAZ), vessel flow density of superficial capillary plexus(SCP) and deep capillary plexus(DCP) in the macular area(3×3mm). The latest version of microperimeter, MP-3, was used to quantitate retinal light sensitivity and fixation stability in the central 10° of the macular region.

Results

The NPDR group had a larger FAZ area, reduced vessel flow densities of both SCP and DCP, deceased retinal sensitivity and less stable fixation compared with the control group. Statistical differences were only found in the FAZ area, vessel flow density of DCP and retinal sensitivity between the NDR and the NDPR group.

Conclusions

The FAZ enlargement, vessel flow density decrease and retinal sensitivity reduction may be morphological and functional indicators of progression of diabetic retinopathy. Microvascular alterations in deep capillary plexus may precede superficial capillary alterations in diabetic retinopathy.
Internal limiting membrane insertion technique combined with nerve growth factor injection for large macular hole
Authors: Zhang Luyi , Li Xiaoxia , Yang Xiaoli , Shen Yu , Wu Miaoqin 
Published: May 2019

Abstract
Background

The study was proposed to determine whether the nerve growth factor (NGF) combined with an internal limiting membrane (ILM) insertion technique was effective in the large idiopathic full-thickness macular hole (iFTMH) surgery.

Methods

A subset of 18 eyes (July 2015-October 2017) diagnosed as a large iFTMH were enrolled in this study. The subjects were treated using ILM insertion technique alone (ILM group) or ILM combined with NGF injection (NGF group) and the follow-up period was 6 months. Macular hole closure rates, best-corrected visual acuity (BCVA, improvements using ETDRS), and optical coherence tomography (OCT) findings were analyzed at 1, 3, and 6 months postoperatively.

Results

We found that macular hole in both groups are fully closed. In comparison to ILM insertion group, the NGF group had better BCVA at the 3-month (48.00 ± 2.392 vs 58.22 ± 2.957, 95% confidence interval (CI): 2.159 to 18.29). The mean external limiting membrane (ELM, 422.2 ± 96 vs 674.9 ± 103.6, 95% CI: -47.26 to 552.8) and ellipsoid zone (EZ, 496.7 ± 101.6 vs 766.7 ± 111.8, 95% CI: -50.29 to 590.4) defects were significantly smaller in the NGF group at the 6-month follow-up examination. Complete recovery of ELM and EZ was observed in the NGF group in one eye of a patient and two eyes of two patients, respectively. In comparison to that, one eye’s ELM and another eye’s EZ was completely recovered in the ILM insertion group.

Conclusion

Our results indicated that ILM insertion with NGF injection might be an effective technique for the initial surgical treatment of eyes with large MHs. The proposed approach yielded better recovery of the photoreceptor layers and consequently superior postoperative visual acuity.
Differentially expressed microRNAs under imidacloprid exposure and identification in Sitobion avenae
Authors: Chen Xi-Ling , Zhang Baizhong , Liu Junjie , Lu Liuyang , Xie Lanfen , Zhang Shouping 
Published: May 2019

Abstract
Backgroud: MicroRNAs (miRNAs), which are as short single-stranded non-coding RNAs, coudl regulate the expression of target genes, especially regulation or metabolism of endogenous or xenobiotic compounds.
Results: The de novo assembly of the transcriptomes was obtained through Illumina short-read sequencing technology in Sitobion avenae. 57 miRNAs, of which 36 were known and 21 were novel were identified. Quantitative expression levels of miRNA showed that the expression of 5 miRNAs were significant up-regulation, and the expression of 11 miRNAs were significant down-regulation in the nymph of S. avenae treated by imidacloprid in comparison with the control, respectively. The candidate transcript target genes in S. avenae that could be regulated by these miRNAs were also carried out. The functions of the miRNAs, which could potentially regulate the target genes participated in the metabolism, regulatory or detoxification of S. avenae were clarified based on Gene Ontology and KEGG pathway. The effects of the miRNAs identified api-miR-1000, api-miR-316, and api-miR-iab-4 on susceptibility of S. avenae to imidacloprid was determined. The abundance of api-miR-1000, api-miR-316, and api-miR-iab-4 modulated by the addition of their own inhibitors to the artificial diet could change significantly the susceptibility of S. avenae to imidacloprid, which further proved that the regulatory affect of these miRNAs on regulation or metabolism of insecticides.
Conclusion: It suggested that differentially expressed microRNAs under the stress of imidacloprid could play critical regulatory role in the resistance of S. avenae to imidacloprid.
De novo transcriptome assembly of four organs of Collichthys lucidus and identification of genes involved in sex determination and reproduction
Authors: Song Wei , Zhang Yi-Bing , Zhang Xiao-Juan , Gui Jianfang 
Published: May 2019

Abstract
Background

Spinyhead croaker (Collichthys lucidus) is an important kind of fish for commercial fishery because of its delicious meat and abundant resource. However, the resource has been declining with the overfishing and environmental disruption. Unfortunately, the mechanism of sex determination and reproduction in Collichthys lucidus is still confusing, which has largely hindered molecular regulation and reproduction studies.

Results

Based on transcripts sequencing in brain, liver, ovary and testis, a de novo transcriptome assembly of Collichthys lucidus was performed. Totally, 131,168 non-redundant unigenes with an average length of 644 bp and an N50 value of 1033 bp, among which 2,143, 304, 333 and 556 were found specifically expressing in brain, liver, ovary and testis, respectively. Importantly, 1288 genes were differently expressed between ovary and testis, including 442 up- and 846 down-regulated in ovary. The differently expressed genes were involved in function of sexual reproduction, sex differentiation, development of primary male sexual characteristics, female gamete generation, and male sex differentiation. HYAL and SYCP3, two genes which were reported to play dominant roles in reproduction, may regulated the key of fertilization and meiosis in Collichthys lucidus. Meanwhile, 35,476 simple sequence repeats (SSRs) were identified, which would contribute to further genetic and mechanism researches.

Conclusions

The studies of genetic information, molecular regulation and reproduction of Collichthys lucidus would be expand due to the sequencing and de novo assembling on the transcripts of major organs. In addition, the identification of candidate genes involved in reproduction will be useful for protecting the resource of Collichthys lucidus.
STARY FORDON – A DISCUSSION ON BEAUTY OF PUBLIC SPACE DESIGN AND USERS EXPECTATIONS
Authors: RACZYŃSKA-MĄKOWSKA Ewa 
Published: May 2019

Abstract
The aim of the research conducted by the author in 2016 and 2017, was to define the performance path for the development of public space, and namely the Stary Fordon Town Square, today’s district of Bydgodszcz, which before 1973 was an independent town. A design and conceptual programme was performed whilst stimulating the residents’ activity and in dialogue with them, together with the Design Specialization students from the UTP University of Science and Technology in Bydgoszcz. Student design and research suggestions made it possible to organise a national architectural design competition in 2017 for a Town Square design. The competition objectives were formed on the basis of research, which were used in the process of creating student concepts, which constituted an interim phase between subjectification of residents’ expectations and the final design. This method gave rise to a design of an accepted space, which was expected by all interested parties. Post factum discussions and even protests frequently seen in such undertakings were avoided by the application of the participation method in the initial phase of preparations. Nevertheless, this is the most appropriate solution for cooperation between a university and the local administration.
THE COMPARATIVE ANALYSIS OF MUNICIPAL SOLID WASTE MANAGEMENT IN THE EIGHT CITIES OF UKRAINE
Authors: PAVLIUK Nonna 
Published: May 2019

Abstract
A simplified solid waste management system has existed for many years in Ukraine being. The system factually coming to MSW collection and their removal to landfills and dumps. This has resulted in accumulation of 223 million tons MSW on territory of more than 8.5 ha.
Signing on 27th June 2014 EU-Ukraine Association Agreement obliged Ukraine to approximate legislation to EU demands in the Field of Waste Management [1]. On 8th November 2017 National Waste Management Strategy has been accepted for this purpose binding until 2030 [2].
This paper makes a comparative study of Municipal Solid Waste (hereinafter referred to as MSW) Management in Ukraine. This paper represents the analysis of the waste composition from the eight cities from different regions of Ukraine. The comparative analysis takes into account dependence of the amount and waste composition on income and population level. The approaches of the World Bank basic report are used in this study [3]. The study reveals prospects for development of techniques on material and energy use of MSW potential in Ukraine.