bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a multicomponent psychological mobile application (app) for patients with acute myeloid leukemia (AML).
Authors: El-Jawahri Areej , Greer Joseph , Wright Emily M. , Vanbenschoten Olivia , Waldman Lauren , Temel Jennifer S. 
Published: November 2018

166 Background: Patients newly diagnosed with AML experience substantial psychological distress as they confront a life-threatening diagnosis requiring an urgent 4-6 week hospitalization to initiate chemotherapy. Interventions to address psychological distress in this population are lacking. Methods: We used a five-step app development process to create a psychological intervention app targeting patients’ needs during the initial hospitalization following a new diagnosis of AML. Patients, caregivers, oncologists, psychologists, and nurses served as stakeholders and were involved in 1) developing a conceptual framework for the intervention; 2) creating an intervention manual that incorporates medical information, psychoeducation, and psychosocial skill-building corresponding to the illness trajectory; 3) translating the intervention manual into a storyline with gamification to enhance patient engagement; 4) creating initial wireframes of the app modules; and 5) refining the app through iterative testing. Results: The app consists of five 20-minute modules which the patient will complete weekly over a 5-week period. The modules consist of 1) supportive psychotherapy to address the initial shock of diagnosis; 2) psychoeducation to manage expectations and mobilize social supports; 3) psychosocial skill-building to promote effective coping; 4) self-care to promote positive health behaviors; and 4) a summary module to reinforce learning points from prior modules. Two bonus modules are available for patients who wish to engage in additional cognitive-based restructuring strategies. We utilized gamification strategies to enhance patient engagement including a) creating an app storyline focused on the patient’s journey during hospitalization; 2) creating a guide character doctor that accompanies the patient through their journey; 3) incorporating videos of AML survivors; and 4) developing a point reward system for completing the modules. Conclusions: We developed a novel psychological intervention app for patients with AML using an iterative development process. Future studies should assess the efficacy of the app in improving outcomes for patients with AML.
Contemporarity
Authors: McFadden Patricia 
Published: November 2018

Abstract
This essay theorizes contemporarity as a new framework for Black feminist resistances—personal and sociopolitical—and explores reimagined lived realities as a crucial site for the generation of new feminist epistemologies and alternative ways of living. Given the failures of neocolonial and neoliberal state regimes across the African continent and the globe to respond equitably to the imperatives of human emancipation, the paper argues for a return to and closer interrogation of personal politics and feminist relationships to the self and the ecosystems that nurture both. The challenge is to find new sources of creative imaginaries and resistance that will lead to the unfolding of discourses, practices, and ways of living that offer an alternative to neoliberal capitalism. From the experience of sustaining oneself through ecological balance, a respectful interaction with nature, and nonmarket practices of sufficiency, the paper proposes to glean the knowledge and inherent integrity embedded in such processes to create new radical social knowledge and practices.
In vitro inhibitory and biofilm disruptive activities of ginger oil against Enterococcus faecalis
Authors: Mohd-Said Shahida , Kweh Wee Wee , Than Chong Yi , Zainal-Abidin Zamirah , Adnan Siti Noor Adnalizawati , Baharin Safura Anita , Soo Eason 
Published: November 2018

Background: This study investigated the antibacterial effect of ginger (Zingiber officinale) oil against a common resistant root canal pathogen known as Enterococcus faecalis. The aim of the study was to determine the inhibition of E. faecalis growth in culture suspension and ability to inhibit growth of bacteria through disruption of pre-formed monospecies biofilm. Methods: Ginger rhizome oil was prepared in two-fold concentration series from 0.04 to 5.00 mg/mL and mixed with brain heart infusion broth inoculated with E. faecalis in anaerobic condition. Among the antibacterial tests performed were the minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations using microdilution assays, and anti-biofilm assay on 3-day old pre-form monospecies biofilm on a 94 well-plate. Ampicillin was used as a positive control. Results: The result showed an in vitro dose-dependent bacteriostatic activity towards E. faecalis in suspension broth (MIC 0.04mg/mL) but no bactericidal activity within the tested concentration range. It was also found that the ginger oil inhibitory activity against E. faecalis was comparably less in anti-biofilm activity than against bacteria cultured in suspension solution. Conclusion: The study suggests that at determined concentrations, ginger oil has the potential to be used as an antibacterial agent in the management of root canal infections particularly where newly formed E. faecalis is involved.
ОЦЕНКА КОМПОНЕНТОВ СТРЕСС-РEЗИСТЕНТНОСТИ У ЮНОШЕЙ И ДЕВУШЕК ТУВИНСКОГО УНИВЕРСИТЕТА
Authors: Buduk-ool Larissa Kara Salona , Hovalyg Ayana Mangushevna 
Published: November 2018

Цель. Изучить показатели стресс-резистентности юношей и девушек Тувинского государственного университета.Материалы и методы. В исследовании приняли участие 236 студентов-первокурсников Тувинского государственного университета, средний возраст 19,40,1 лет. Определяли индексы стресса и морфофункционального состояния, скорость биологического старения, цену адаптации и адаптационные возможности организма. Оценка реактивной (РТ) и личностной (ЛТ) тревожности проводилась по опроснику Ч.Д. Спилбергера в модификации Ю.Л. Ханина [10] по «НС-Психотест» ООО «Нейрософт».Результаты. Высокий уровень РТ выявлен у 1,3% девушек (у юношей таковые отсутствуют), а ЛТ – у 45% девушек и всего 19,5% юношей (р≤0,05). У девушек выше (55,8%) доля лиц характеризующихся сниженным уровнем функционального состояния. 7,0% девушек и 13,6% юношей (р≤0,05)имеют скорость биологического старения выше возрастной нормы, 2,3% девушек характеризуются состоянием некомпенсированного дистресса, среди юношей таковые отсутствуют. Высокая цена адаптации, связанная с напряженным периодом жизни, с повышением затраты энергии наблюдается у 9,1% юношей и 7,0% девушек.Заключение. Таким образом, проведенное исследование показателей стрессоустойчивости позволило выявить более высокие ЛТ и РТ, стрессового напряжения в сочетании с низкими показателями адаптивных возможностей организма и морфофункционального состояния у девушек, однако у них меньше скорость биологического старения организма. Студенты-юноши при высоких показателях морфофункционального состояния, низкой тревожности и напряжения, характерных для состояния эустресса с оптимальным уровнем реагирования на стрессирующие факторы, обладают более высокими адаптивными возможностями организма.
Comparison of minimally invasive and non-invasive systems in lengthening total femoral prostheses
Authors: Medellin M. R. , Fujiwara T. , Clark R. , Jeys L. M. 
Published: November 2018

AimsThe aim of this study was to describe, analyze, and compare the survival, functional outcome, and complications of minimally invasive (MI) and non-invasive (NI) lengthening total femoral prostheses.Patients and MethodsA total of 24 lengthening total femoral prostheses, 11 MI and 13 NI, were implanted between 1991 and 2016. The characteristics, complications, and functional results were recorded. There were ten female patients and ten male patients. Their mean age at the time of surgery was 11 years (2 to 41). The mean follow-up was 13.2 years (seven months to 29.25 years). A survival analysis was performed, and the failures were classified according to the Modified Henderson System.ResultsThe overall implant survival was 79% at five, ten, and 20 years for MI prostheses, and 84% at five years and 70% at ten years for NI prostheses. At the final follow-up, 13 prostheses did not require further surgery. The overall complication rate was 46%. The mean revision-free implant survival for MI and NI prostheses was 59 months and 49 months, respectively. There were no statistically significant differences in the overall implant survival, revision-free survival, or the distribution of complications between the two types of prosthesis. Infection rates were also comparable in the groups (9% vs 7%; p = 0.902). The rate of leg-length discrepancy was 54% in MI prostheses and 23% in NI prostheses. In those with a MI prosthesis, there was a smaller mean range of movement of the knee (0° to 62° vs 0° to 83°; p = 0.047), the flexion contracture took a longer mean time to resolve after lengthening (3.3 months vs 1.07 months; p < 0.001) and there was a lower mean Musculoskeletal Tumor Society (MSTS) score (24.7 vs 27; p = 0.295).ConclusionThe survival and complications of MI and NI lengthening total femoral prostheses are comparable. However, patients with NI prosthesis have more accurate correction of leg-length discrepancy, a better range of movement of the knee and an improved overall function.
Prognostic factors for local recurrence in extremity-located giant cell tumours of bone with pathological fracture
Authors: Medellin M. R. , Fujiwara T. , Tillman R. M. , Jeys L. M. , Gregory J. , Stevenson J. D. , Parry M. , Abudu A. 
Published: November 2018

Aims The aim of this paper was to investigate the prognostic factors for local recurrence in patients with pathological fracture through giant cell tumours of bone (GCTB). Patients and Methods A total of 107 patients presenting with fractures through GCTB treated at our institution (Royal Orthopaedic Hospital, Birmingham, United Kingdom) between 1995 and 2016 were retrospectively studied. Of these patients, 57 were female (53%) and 50 were male (47%).The mean age at diagnosis was 33 years (14 to 86). A univariate analysis was performed, followed by multivariate analysis to identify risk factors based on the treatment and clinical characteristics. Results The initial surgical treatment was curettage with or without adjuvants in 55 patients (51%), en bloc resection with or without reconstruction in 45 patients (42%), and neoadjuvant denosumab, followed by resection (n = 3, 3%) or curettage (n = 4, 4%). The choice of treatment depended on tumour location, Campanacci tumour staging, intra-articular involvement, and fracture displacement. Neoadjuvant denosumab was used only in fractures through Campanacci stage 3 tumours. Local recurrence occurred in 28 patients (25%). Surgery more than six weeks after the fracture did not affect the risk of recurrence in any of the groups. In Campanacci stage 3 tumours not treated with denosumab, en bloc resection had lower local recurrences (13%), compared with curettage (39%). In tumours classified as Campanacci 2, intralesional curettage and en bloc resections had similar recurrence rates (21% and 24%, respectively). After univariate analysis, the type of surgical intervention, location, and the use of denosumab were independent factors predicting local recurrence. Further surgery was required 33% more often after intralesional curettage in comparison with resections (mean 1.59, 0 to 5 vs 1.06, 0 to 3 operations). All patients treated with denosumab followed by intralesional curettage developed local recurrence. Conclusion In patients with pathological fractures through GCTB not treated with denosumab, en bloc resection offers lower risks of local recurrence in tumours classified as Campanacci stage 3. Curettage or resections are both similar options in terms of the risk of local recurrence for tumours classified as Campanacci stage 2. The benefits of denosumab followed by intralesional curettage in these patients still remains unclear.
EQUAÇÃO DE LONGEVIDADE PARA SEMENTES DE JABUTICABA (Myrciaria jaboticaba (Vell.) O. Berg)
Authors: Sinício Roberto , Bhering Maria Carmem , Vidigal Déborah De Souza 
Published: November 2018

Objetivou-se equacionar o desvio padrão da frequência de distribuição de sementes mortas de jabuticaba durante o período de armazenamento (σ), com base no modelo de probit. Valores obtidos experimentalmente, adicionados a dados da literatura de curvas de sobrevivência de sementes de jabuticaba, armazenadas sob diferentes teores de água e temperaturas, foram transformados em probit e utilizados em regressões lineares e não lineares para determinação dos coeficientes de equação de longevidade. Os coeficientes da melhor equação obtida foram determinados usando os valores da perda de germinação, da germinação inicial no lugar de Ki, da temperatura, do teor médio de água das sementes e do período de armazenagem, para todas as curvas de sobrevivência, conforme segue: σ = 10 ( f0 + f1 m + f2 m2 + f3 m3 + f4 t2 + f5 m.t ) em que: f0 = -98,349, f1 = 6,0973, f2 = -0,12224, f3 = 0,00081249, f4 = 0,058075, f5 = 0,0099939.
A equação obtida foi ajustada com razoável precisão (coeficiente de determinação de 0,873, desvio padrão de 12,3% e grau de significância dos coeficientes da equação menor que 0,1% de probabilidade de erro no teste t, para 72 observações experimentais).
COMPORTAMENTO AGROCLIMÁTICO E EFEITOS DA ÉPOCA DE APLICAÇÃO DE ADUBAÇÃO NITROGENADA NA CULTURA DE ARROZ DE TERRAS ALTAS NO ESTADO DE MATO GROSSO - DOI: 10.13083/1414-3984.v22n03a04
Authors: Fenner William , Dallacort Rivanildo , Modolo Alcir José , Júnior Santino Seabra , Dias Vanessa Rakel de Moraes 
Published: November 2018

O objetivo do presente trabalho foi avaliar o parcelamento de doses de nitrogênio aplicadas em cobertura no sistema de sequeiro e o comportamento agronômico da cultura por meio do monitoramento climático. O trabalho foi realizado na área experimental do Campus da Universidade do Estado de Mato Grosso – UNEMAT, localizada no município de Tangará da Serra (Latitude 14o39’ S, Longitude 57o25’ W e altitude de 321,5 m). Foi adotado o delineamento inteiramente casualizado, com 5 tratamentos e 6 repetições. Os tratamentos se constituíram de doses de nitrogênio parceladas em cobertura em duas épocas (D1: 0/60, D2: 20/40, D3: 30/30, D4: 40/20; D5: 60/0 kg ha-1 de N), aplicados
a lanço no início da fase de perfilhamento e no início da diferenciação floral (15 e 45 dias após a emergência).
As variáveis analisadas foram altura de planta, número de perfilhos, espiguetas por panícula, panículas por m2,
produtividade e peso de 1000 grãos. Durante a pesquisa, também foi realizado o acompanhamento do comportamento
agronômico da cultura, analisando-se as variáveis: temperatura do ar, precipitação e cálculo da soma térmica e a
realização do balanço hídrico da cultura. A adoção do parcelamento de adubações nitrogenadas em cobertura não
proporcionou incrementos significativos na produtividade no arroz de sequeiro, quando a cultura sofre influência de baixos índices pluviométricos. Os meses de novembro e março apresentaram valores de precipitação abaixo dos ideais para a obtenção de produtividades satisfatórias no período analisado. Considerando-se apenas o fator temperatura do ar, no município de Tangará da Serra não há restrição ao cultivo do arroz.
INFLUÊNCIA DA EMBALAGEM E DO LOCALDE ARMAZENAMENTO NA QUALIDADE FISIOLÓGICA DE SEMENTES DE ABÓBORA ‘JACAREZINHO’ (Curcubita moschata Duch). - DOI: 10.13083/1414-3984.v22n04a02
Authors: Figueiredo Neto Acácio , Dantas Bárbara França , Almeida Francisco De Assis Cardoso , Lima Marcos Santos , Silva Fabrício Francisco Santos da 
Published: November 2018

As condições de armazenamento são determinantes para garantia da qualidade fisiológica das sementes e, embora a sua qualidade não possa ser melhorada, boas condições durante este período contribuirão para mantê-las viáveis por um tempo mais longo, retardando o processo de deterioração. A manutenção da viabilidade das sementes de frutos carnosos
através do armazenamento vem sendo uma das linhas de pesquisa mais importantes para as sementes de grande número de espécies. Diante do exposto, objetivou-se com o presente trabalho avaliar a influência dos diferentes tipos de embalagens, ambientes, e do período de armazenamento sobre a germinação e vigor das sementes de abóbora ‘Jacarezinho’. O trabalho foi conduzido no Laboratório de Análise de Sementes da Embrapa Semiárido, em Petrolina – PE. As sementes foram acondicionadas em embalagens de papel e de plástico (tereftalato de polietileno) e mantidas em ambiente de laboratório e em câmara fria com 10 oC e 45% de UR. As sementes foram avaliadas antes e durante o armazenamento por três, seis e doze meses. Foram avaliados o teor de água, a germinação e o vigor das sementes. Dentre os principais resultados, pode-se constatar que é viável armazenar sementes de abóbora ‘Jacarezinho’ com 6% de teor de água durante doze meses, pois a dormência endógena é superada após este período de conservação. A embalagem de plástico foi considerada a mais adequada assim como o ambiente de laboratório com 29 oC e 45% de UR para as condições climáticas de Petrolina - PE. Os maiores valores de germinação foram obtidos em embalagem de plástico (95%) para os doze meses e papel com 91%, no terceiro mês de armazenamento. A análise de correlação entre o peso seco das sementes (r = -0,80) e o teste frio (r = 0,76) com a emergência de plântulas em campo foi significante a 1% de probabilidade.
INFLUÊNCIA DA TEMPERATURA DE SECAGEM SOBRE AS PROPRIEDADES FÍSICAS DOS GRÃOS DE SOJA - DOI: 10.13083/1414-3984/reveng.v23n3p212-219
Authors: Botelho Fernando Mendes , Granella Suian José , Botelho Sílvia De Carvalho Campos , Garcia Taise Raquel Bechlin 
Published: November 2018

Objetivou-se com o presente trabalho avaliar o efeito da temperatura de secagem sobre algumas propriedades físicas de grãos de soja. Para avaliar o efeito da temperatura, amostras de grãos de soja com teor inicial de água de 0,244 (b.s.) foram secadas numa estufa com circulação forçada de ar nas temperaturas de 40, 50, 60, 70 e 80 °C até o teor final de água de 0,136 (b.s.), sendo então determinadas as propriedades físicas: ângulo de repouso, massa específica aparente, massa específica unitária, massa de mil grãos, cor e condutividade elétrica da solução dos exsudatos dos grãos. Notouse que, à exceção da porosidade, a temperatura do ar de secagem influenciou significativamente as propriedades físicas de grãos de soja, proporcionando aumento do ângulo de repouso e da condutividade elétrica da solução dos exsudatos. As massas específicas aparente e unitária, massa de mil grãos e a cor característica dos grãos de soja diminuíram com o aumento da temperatura do ar empregado na secagem. Concluiu-se que o aumento da temperatura do ar de secagem
diminuiu a qualidade dos grãos de soja analisados.
Cardiovascular Disease and Frailty: What Are the Mechanistic Links?
Authors: Stewart Ralph 
Published: November 2018

AbstractBACKGROUNDIn aging populations, cardiovascular disease (CVD) and frailty are common and often coexist. It is possible that common risk factors and pathophysiological pathways increase the risk of both CVD and frailty.CONTENTFrailty is a complex clinical syndrome with multiple causes and contributing factors. It is characterized by multisystem impairment that decreases physiological reserve and increases vulnerability to stress. Diverse methods have been used to evaluate frailty. Most include 1 or several measures related to reduced exercise, physical function, cognition, activities of daily living, comorbidities, deficits and/or markers of physiological dysfunction. CVD and frailty may be linked by several mechanisms. CVD can accelerate frailty, and frailty increases the risk of adverse outcomes in patients with CVD. Common pathophysiological pathways are also important. Low physical activity, poor nutrition, diabetes, hypertension, and smoking may increase the risk of both CVD and frailty. Further research is needed to evaluate whether biomarkers of dysfunction across multiple body systems, which are known to be associated with aging, and with CV and non-CV morbidity and mortality, are also associated with frailty.SUMMARYMultiple pathophysiological pathways are associated with both CVD and frailty, which interact to further increase the risk of adverse outcomes.
Minimally invasive approach to diastema closure using lithium disilicate porcelain veneers: clinical report
Authors: Buzetto Sofia Chane , Pedreira Priscila Regis , Damasceno Janaina Emanuela , Pierote Josué Junior Araujo , Marchi Giselle Maria , Paulillo Luiz Alexandre Maffei Sartini 
Published: November 2018

Numerous advances in dentistry techniques and material have allowed patients to have not only a functional but also an aesthetic smile in a conservative way. This case report describes a treatment with ceramic laminates to solve the aesthetic problems of an 18-year-old male dissatisfied with his smile. Following the correct protocols, using minimally invasive abrasions, ceramic laminates, and strong adhesion between porcelain and dental enamel can provide predictable results and clinical longevity through follow-up.KeywordsDental veneers; Ceramic; Dental materials.
Mandibular involvement as a first sign in Multiple Myeloma: a case report
Authors: Raut Mugdha , Bansal Shivani , Sharma Ankit , Desai Rajiv 
Published: November 2018

Objective: To report a case of Multiple myeloma (MM) in mandible with paraesthesia. Material and Methods: The present case report highlights the occurrence of a swelling in the left posterior mandibular region in a 70-year old female patient and draws attention to the first clinical sign of a widespread systemic disease manifesting in the head and neck region. Results: The initial presumptive diagnosis was invalidated by the histopathological examination and other diagnostic tests that revealed the features characteristic for MM. Conclusion: Being a rare disease, MM should be kept on forefront of differential diagnosis for jaw lesions in a geriatric patient with paraesthesia.Keywords: Multiple myeloma; Mandible; Paraesthesia.
Reflexões sobre ensino de biblioteconomia: ênfase curricular na função educacional do serviço de referência e da competência em informação
Authors: Mata Marta Leandro da , Gerlin Meri Nadia Marques 
Published: November 2018

As disciplinas de formação específica são o núcleo base da profissão, constituindo-se, principalmente, da área de organização e representação da informação e do conhecimento, permitindo a organização, a recuperação, a disseminação e o acesso à informação pelos usuários. À vista disso, o presente artigo pretende refletir sobre o percurso do ensino de Biblioteconomia no Brasil desde o estabelecimento da profissão com seu primeiro currículo mínimo até as Diretrizes Curriculares Nacionais, com ênfase curricular na formação de usuários, isto é, desde o oferecimento de disciplinas de Serviço de Referência, Educação de Usuários e Competência em Informação. Por meio de um levantamento teórico, no âmbito da Biblioteconomia e da Ciência da Informação, identificou-se que os bibliotecários, além de trabalharem com as atividades de organização e tratamento da informação nas unidades de informação, também devem dedicar-se aos serviços voltados aos usuários, por exemplo, na implementação de programas de competência em informação nas instituições de ensino, já que, estes profissionais possuem um papel fundamental em relação aos processos educativos do universo informacional, contribuindo para o processo de ensino-aprendizagem dos indivíduos.