bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variable Features of Juvenile Polyposis Syndrome With Gastric Involvement Among Patients With a Large Genomic Deletion of BMPR1A
Authors: Lieberman Sari , Beeri Rachel , Walsh Tom , Schechter Menachem , Keret Dan , Half Elizabet , Gulsuner Suleyman , Tomer Ariela , Jacob Harold , Cohen Shlomi , Basel-Salmon Lina , Mansur Mahmud , Berger Rachel , Katz Lior H. , Golomb Eliahu , Peretz Tamar , Levy Zohar , Kedar Inbal , King Mary-Claire , Levy-Lahad Ephrat , Goldberg Yael 
Published: June 2019

OBJECTIVES:
Loss-of-function mutations of BMPR1A cause juvenile polyposis syndrome (JPS), but large genomic deletions in BMPR1A are rare, reported in few families only, and data regarding the associated phenotype are limited.

METHODS:
We investigated clinical features and genomic data of 7 extended seemingly unrelated families with a genomic deletion of the entire coding region of BMPR1A. We defined mutation size, mutation prevalence, and tumor pathogenesis using whole-genome sequencing, targeted genotyping, and haplotype analysis.

RESULTS:
Patients with JPS from 7 families of Bukharin Jewish ancestry carried a deletion of 429 kb, encompassing the BMPR1A coding sequence and 8 downstream genes. Haplotype analysis and testing controls identified this as a common founder mutation occurring in 1/124 individuals of Bukharin origin. Tumor testing did not demonstrate loss of heterozygosity. Among carriers, JPS was almost fully penetrant, but clinical features varied widely, ranging from mild to very severe, including pan-enteric polyps, gastritis, and colorectal, esophageal, and testicular cancer, and carriers with phenotypes, which would not have raised suspicion of JPS.

DISCUSSION:
The phenotype in this large cohort was extremely variable, although all carriers shared the same variant and the same genetic background. New observations include a preponderance of adenomatous rather than juvenile polyps, possible association with testicular cancer, and unexpected upper gastrointestinal involvement.
BİST KİMYA, PETROL KAUÇUK VE PLASTİK ÜRÜNLER SEKTÖRÜNDEKİ İŞLETMELERİN FİNANSAL PERFORMANSLARININ HİBRİD ÇKKV YAKLAŞIMI ÇERÇEVESİNDE DEĞERLENDİRİLMESİ
Authors: ÇANAKÇIOĞLU Mustafa 
Published: July 2019

Bu çalışmada Borsa İstanbul (BIST) imalat sanayinde yer alan kimya, petrol kauçuk ve plastik ürünler sektöründe yer alan firmaların oran analizi yaklaşımı ile birbirleriyle karşılaştırmalı finansal performans analizi yapılmıştır. Çalışma kapsamında 30 işletmenin 2013-2017 tarihleri arasındaki temel mali tablolardan elde edilen 10 finansal oran kriteri kullanılmıştır. Elde edilen veriler “Çok Kriterli Karar Verme” (ÇKKV) yöntemlerinden Entropi ve Gri İlişkiler Analiz (GİA) ile değerlendirilmiştir. Belirlenen seçim kriterlerinin ağırlıkları Entropi tekniği kullanılarak hesaplanmıştır. Ardından GİA yöntemi kullanılarak karar seçeneklerinin göreli önem değerleri hesaplanmış, firmalar her yılın performans değerlerine göre sıralandırılmıştır. Son olarak Borda metodu kullanılarak firmalar tüm yıllara göre yeniden sıralandırılmıştır.
TÜKETİCİ ETNOSENTRİZMİ VE ÜLKE MENŞEİ ETKİSİNİN YABANCI MARKALI ÜRÜN SATIN ALMA NİYETİ ÜZERİNE ETKİSİ
Authors: AYDOĞAN Sibel 
Published: July 2019

Tüketici etnosentrizmi (etnik merkezcilik), tüketicilerin bireysel özelliklerine ve onların niyetlerine, tercihlerine, satın alma davranışlarını etkileyen tutumlarına odaklanır. Ürünün menşe ülkesi ve dolayısıyla menşe ükenin imajı satın alma aşamasında tüketici algısında olumlu ya da olumsuz çağrışımlar yapabilmekte ve bu da satın alma kararını etkileyebilmektedir. Eğer ürünün üretildiği ülke tüketici zihninde olumlu çağrışımlar yaratıyorsa bu durum ürünün imajının da olumlu olmasına neden olmakta ve satın almayı pozitif yönde etkilemektedir. Bu çalışmanın temel amacı öncelikle tüketicilerin etnosentrizm derecesini belirlemektir. Tüketici etnosentrizmi ile menşe ülkenin tüketicilerin yabancı markalı ürünlere yönelik satın alma niyetleri üzerindeki etkisinin değerlendirilmesi ise çalışmanın bir diğer amacıdır. Bu bağlamda kolayda örnekleme yöntemi ile 605 kişiye ulaşılmıştır. Çalışmaya göre, tüketici etnik merkezcilik ortalaması, orta düzeyde eğilimi gösteren 49,17 sayısıdır. Ülke Menşei Etkisi ile Tüketici Etnosentrizmi arasında pozitif yönlü bir ilişki görülmüştür. Tüketici Etnosentrizmi ile yabancı marka çay satın alma niyeti arasında ise negatif yönlü bir ilişki vardır.
Risk factors of regional lymph node metastasis in patients with cervical cancer
Authors: Wu Chunchun , Li Lichun , Xiao Xue , Sun Anyi , Lin Wenji , Li Ailu 
Published: June 2019

AbstractObjectivesTo explore the risk factors related to regional lymph node metastasis in cervical cancer and analyze the value of independent risk factors in predicting regional lymph node metastasis.MethodsWe retrospectively analyzed the clinical data of 699 patients who underwent surgery for stage IB1–IIA2 cervical cancer in Quanzhou First Hospital affiliated to Fujian Medical University from 2010 to 2016. The patients were divided into metastasis (n = 92) and non-metastasis (n = 607) groups based on the postoperative pathology of regional lymph node status. The relevant clinicopathological features of the metastasis and non-metastasis groups were compared through variance analysis and chi-square tests. Logistic regression was adopted to screen relevant independent risk factors of regional lymph node metastasis.ResultsIn univariate analysis, International Federation of Gynecology and Obstetrics (FIGO) stages, serum squamous cell carcinoma antigen (SCC-Ag), histological type of squamous carcinoma and maximal tumor diameter were related factors for lymphatic metastasis in patients with cervical cancer. In multivariate analysis, SCC-Ag and histological type of squamous carcinoma were independent prognostic factors for lymphatic metastasis in patients with cervical cancer. Pre-treatment SCC-Ag serum levels, as a predictor of lymph node metastasis of cervical cancer, revealed a sensitivity of 62.07% (95% confidence interval (CI): 51.03–72.62%), specificity of 65.15% (59.07–70.89%), and area under the receiver operating characteristic (ROC) curve of 0.69 (95% CI: 0.61–0.76).ConclusionsCervical cancer patients whose pathological type is squamous carcinoma with high levels of SSC-Ag pre-operation are more likely to be diagnosed with regional lymph node metastasis. Standardized lymph node dissection should be implemented during operation.
Values and Attitudes in Banat Multiethnic Communities
Authors: Dabu Ileana Simona 
Published: July 2019

Abstract
The Banat area is considered an area of interculturality and multilingualism, an area where there is an interference of cultures, a continuous dialogue between cultures and spiritualties. Banat, being a multicultural and multiethnic space, is a model of harmonious coexistence between the many ethnic groups that make it up. In the present research we have aimed at identifying the individual values of the inhabitants of the studied communities and the attitudes towards the others (Romanians, Serbs, Hungarians, Germans, Bulgarians and other ethnic groups), and also their attitudes towards work, land, church, trust in state institutions and traditional occupations.
Ex-Offender Reintegration and Sustained Peace in the Niger Delta Region of Nigeria: Adopting a Socio-Economic Change Model Approach
Authors: Ubleble Benjamin A. , Agomoh John M. , Chovwen Anthony 
Published: July 2019

Abstract
The Niger Delta of Nigeria rich in oil and gas resources has been plagued with series of armed conflicts characterised by massive youth restiveness. The peaceful coexistence of people in the region is often affected by the nature of oil and gas business determined by the political economy of the Nigerian state. By the statute of the Federal system of Government in Nigeria, all resources within the territorial boundary of the country belong to the Federal Government. The Government then pays a certain 13% derivation fund to the resource bearing states for development. The Federal Government equally sees to the development of the region through its statutory Agencies such as the Niger Delta Development Commission. All these efforts are yet to bring about infrastructural development and human capacity needs of the region. A consequence of this is the armed militancy and cult related violence that has engulfed the region. In this paper, an attempt is made to analyse the socioeconomic requisitions of a reintegration programme for ex-offenders seeking re-entry into mainstream society. An interventionist approach is recommended with effective monitoring and evaluation system for a socioeconomic reintegration of ex-offenders in the Niger Delta region of Nigeria.
Inverse problem for $2b$-order differential equation with a time-fractional derivative
Authors: Lopushansky A.O. , Lopushanska H.P. 
Published: July 2019

We study the inverse problem for a differential equation of order $2b$ with the Riemann-Liouville fractional derivative of order $\beta\in (0,1)$ in time and given Schwartz type distributions in the right-hand sides of the equation and the initial condition. The problem is to find the pair of functions $(u, g)$: a generalized solution $u$ to the Cauchy problem for such equation and the time dependent multiplier $g$ in the right-hand side of the equation. As an additional condition, we use an analog of the integral condition $$(u(\cdot,t),\varphi_0(\cdot))=F(t), \;\;\; t\in [0,T],$$ where the symbol $(u(\cdot,t),\varphi_0(\cdot))$ stands for the value of an unknown distribution $u$ on the given test function $\varphi_0$ for every $t\in [0,T]$, $F$ is a given continuous function.
We prove a theorem for the existence and uniqueness of a generalized solution of the Cauchy problem, obtain its representation using the Green's vector-function. The proof of the theorem is based on the properties of conjugate Green's operators of the Cauchy problem on spaces of the Schwartz type test functions and on the structure of the Schwartz type distributions.
We establish sufficient conditions for a unique solvability of the inverse problem and find a representation of anunknown function $g$ by means of a solution of a certain Volterra integral equation of the second kind with an integrable kernel.
Note on bases in algebras of analytic functions on Banach spaces
Authors: Chernega I.V. , Zagorodnyuk A.V. 
Published: July 2019

Let $\{P_n\}_{n=0}^\infty$ be a sequenceof continuous algebraically independent homogeneous polynomials on a complex Banach space $X.$ We consider the following question: Under which conditions polynomials $\{P_1^{k_1}\cdots P_n^{k_n}\}$ form a Schauder (perhaps absolute) basis in the minimal subalgebra of entire functions of bounded type on $X$ which contains the sequence $\{P_n\}_{n=0}^\infty$? In the paper we study the following examples: when $P_n$ are coordinate functionals on $c_0,$ and when $P_n$ are symmetric polynomials on $\ell_1$ and on $L_\infty[0,1].$ We can see that for some cases $\{P_1^{k_1}\cdots P_n^{k_n}\}$ is a Schauder basis which is not absolute but for some cases it is absolute.
Efecto de un programa adaptado de educación física en niños con discapacidad auditiva sobre la coordinación motora
Authors: Ochoa-Martínez Paulina Yesica , Hall-López Javier Arturo , Carmona López Abel Alberto , Morales Ramírez Mara Michell , Alarcón Meza Edgar Ismael , Sáenz-Lopez Buñuel Pedro 
Published: June 2019

Objetivo: evaluar el efecto de un programa de educación física adaptado en escolares con discapacidad auditiva sobre el cociente motor.
Método: el diseño del estudio fue cuasiexperimental, con muestreo por conveniencia, participando treinta y ocho niños con una edad promedio de 7.4±0.9 años, diagnosticados con debilidad o pérdida auditiva, de dos escuelas de la ciudad de Mexicali, Baja California. México. Los participantes fueron divididos aleatoriamente en un grupo experimental (n=23) y otro control (n=15), a los cuales se les evaluó el cociente motor mediante el test de coordinación corporal para niños KTK (Körperkoordinationstest für Kinder de Kiphard y Schiling), por sus siglas en alemán, mediante las pruebas: desplazamientos en equilibrio de espaldas, saltos monopódales, saltos laterales y transposición sobre plataforma. El programa se realizó durante 4 meses, 5 veces por semana, con una duración de 50 minutos por sesión, comunicándose con los alumnos mediante el lenguaje de señas mexicano y realizando una serie de tareas que enfatizaran la coordinación motora.
Resultados: al comparar los resultados entre grupos de la variable cociente motor, con el análisis de varianza (ANOVA) mixtas 2 x 2 se observó una interacción doblemente significativa entre los grupos y las mediciones (p = 0.01), los porcentajes de cambio (Δ %) fueron 26 % del grupo experimental y 6.5 %. del grupo control (Δ %).
Conclusión: se establece que la aplicación de un programa de educación física adaptado durante cuatro meses, mejora la coordinación motora en niños con discapacidad auditiva.
Use of the Statistical Comparison Method in a Company's Financial Status Analysis
Authors: Mackevičius Jonas , Tamulevičienė Daiva , Valkauskas Romualdas 
Published: July 2019

General economic, mathematical and heuristic study methods were used when analyzing the financial status of companies. In practice, the comparison method is the most widely applied one of all the general economic research methods. When it is applied, the actual indicators (absolute and relative) are compared to the ones planned inside the company; the indicators of the company are compared with the average ones of the industry or the best ones of other companies; indicators of different periods are compared. However, until now, the comparison method has barely been applied in practice using the averages of certain indicators and especially the multidimensional ones. The aim of the article is to develop a methodology for applying the statistical comparison method based on the calculation and evaluation of the multidimensional average. For achievement of the aim were used research methods: analysis of scientific literature, information collection, aggregation, detailing and summarizing. The article analyzes the significance, advantages and disadvantages of the traditional comparison method. The methodology for the comparison method based on the calculation of the multidimensional average and their comparison is proposed in the article. A concrete example of how to apply the comparison method using the multidimensional average calculation method to assess the financial position of companies is provided.
Attendance Recognation by Using Smart Meter Based On IoT Study Case : FST UIN Jakarta
Authors: Fahrianto Feri , Suseno Hendra Bayu , Reza Alfatta 
Published: June 2019

State Islamic University Syarif Hidayatullah Jakarta as rapidly growing university toward world-class research university placed in the edge of Jakarta has academic information centre running by Pustipanda (The Center of Information Technology and Database). The acadmic information system (AIS) has been used for recording an academic activity in university for almost a decade, this information system has a functionality for detecting the lecturer attandancity, but the attendance system needs to be input by admin. In this research, the system to detect attendancity from lecturer is build and synchronize to universisty academic information system. Internet of Things, based on ITU-T 2015, some objects are able to transmit data among object by using Internet connection. It means by this technology the Internet used has been widely changed, from human to machine communication now also become machine-to-machine communications. By using this technology a small object or device is able to implement into electrical system to detect an activity occured in the room. Things implemented in the room are able to monitor which electronic device is active and motion of moving objects, also the position of objects. The communication connection between smart phones and acces point in the class room is also monitored in order to identify the lecturer identity.
Identifikasi Molekuler Bakteri Endofit Penghasil L-asparaginase yang Diisolasi dari Mangrove Buta-Buta (Excoecaria agallocha)
Authors: Prihanto Asep Awaludin , Ardiansyah Randy Fahrudin , Pradarameswari Ken Audia 
Published: June 2019

AbstrakL-asparaginase (EC 3.5.1.1) adalah enzim yang menghidrolisis asam amino L-asparagin menjadi amonia dan asam aspartat. Enzim ini mempunyai manfaat utama dalam bidang farmasi dan industri pangan. Enzim L-asparaginase tersebar secara luas pada mikroorganisme. Mikroorganisme yang mempunyai potensi menghasilkan enzim ini adalah mikroorganisme endofit dari tumbuhan mangrove. Penelitian ini bertujuan untuk mengisolasi dan mengidentifikasi bakteri endofit penghasil L-asparaginase dari tumbuhan mangrove Buta-buta (E. agallocha). Skrining dilakukan dengan menggunakan medium selektif untuk mendapatkan bakteri penghasil enzim L-asparaginase. Identifikasi molekuler dilakukan dengan menggunakan analisis filogenetik berdasarkan data sekuen 16S rDNA. Dari hasil penelitian ini didapatkan lima isolat bakteri endofit penghasil enzim L-asparaginase, di mana isolat penghasil L-asparaginase tertinggi diidentifikasi secara molekuler. Hasil identifikasi filogenetik molekuler menunjukkan bahwa isolat kode D.104 teridentifikasi sebagai Enterobacter cloacae. Molecular Identification of L-asparaginase-Producing Endophytic Bacteria Isolated from Mangrove Buta-Buta (Excoecaria agallocha)AbstractL-asparaginase (EC 3.5.1.1) is an enzyme which hydrolyze amino acid L-asparagine to aspartate and ammonia. Two main applications of this enzyme are in the pharmaceutical and food industries. The enzyme is widely distributed on microorganism. A potential source of L-asparaginase-producing bacteria is an endophytic bacteria from mangrove plant. This study aimed to isolate and identify L-asparaginase-producing endophytic bacteria from a mangrove plant, E. agallocha (Buta-buta). A screening was carried out using a selective medium to obtain the L-asparaginase enzyme producing bacteria. Molecular identification was carried out using phylogenetic analysis based on 16S rDNA sequence data. In this study, five isolates of the L-asparaginase-producing endophytic bacteria were obtained. The molecular phylogenetic identification showed that the highest L-asparaginase-producing bacterial isolate (code D.104) was identified as Enterobacter cloacae.
Injury and illness profiles during the 2014 South African Ironman triathlon
Authors: Holtzhausen L , Smit C , Joubert G , Von Hagen K 
Published: June 2019

Background: There is a need for ongoing scrutiny of injury and illness profiles of ultra-distance athletes. This study aimed to record the medical history, illness and injuries of athletes receiving medical attention during the 2014 Ironman South Africa (IMSA) triathlon, and to investigate the temporal presentation of medical encounters.
Methods: This was a retrospective, cross-sectional study. All athletes who required medical attention at the main medical tent and all of the medical posts or mobile units along the route were included in this study A total of 2 331 athletes started the race. Data included age, gender, time and stage of the race when medical attention was required, pre-race medical history and medication use, illness and injuries treated, special investigations performed, and weather conditions.
Results: Overall, 179 athletes (7.7%) required medical attention. The incidence of medical encounters was 7.8%. A significantly higher percentage of younger participants encountered medical problems (P = 0.04). Most patient encounters (80.1%) occurred after the race. The median duration of treatment was 26 minutes. Medication was used by 35.1% of patients during the race. The most common medical encounters were exertion-related (71.2%), gastro-intestinal (16.4%), dermatological (11.9%), musculoskeletal (9.6%) and cardiorespiratory conditions (2.4%).
Conclusion: Medical encounters occurred more frequently in later stages of the race. Most medical conditions were exertion-related. Potential higher risk may be associated with medication use, recent illness, and in younger participants. Temporal stacking of medical personnel, planning of resources according to expected conditions, preventative measures for high-risk behaviour, and on-going data collection with comparable methodology are recommended.
Physical performance analysis of elite soccer players during the extra-time periods of the 2016 UEFA Euro Championship
Authors: Kubayi A , Toriola A 
Published: June 2019

Background: Despite the importance of extra-time in determining success in the knockout stages of soccer tournaments, there remains scant information on the physical demands of extra time on elite players.
Methods: This study investigated the physical performance profiles of all soccer players (N=59) who completed four matches that went to extra time at the 2016 UEFA Euro Championship. Players were categorised as follows: central defenders (CDs), wide defenders (WDs), central midfielders (CMs), wide midfielders (WMs), and attackers (ATs). Match activities were captured using a validated camera tracking system (InStat®).
Results: The findings showed that total distances covered by players during matches consistently decreased by 13% from the first half of the game (112.79±10.17 m) to extra time (103.17±6.39 m). The reduction of the total distance covered, especially in high-intensity running (i.e., high-speed running and sprinting), was more apparent in ATs than players in other positions.
Conclusion: Intervention strategies needed to sustain soccer players’ physical performance during extra-time periods and of post-match recovery modalities warrant further investigation.
The impact of anterior knee pain on the quality of life among runners in Ekurhuleni, Gauteng
Authors: Kunene S , Ramklass S , Taukobong N 
Published: June 2019

Background: Anterior knee pain (AKP) is the most common injury among runners and has a negative impact on the quality of life (QOL) of many athletes. Objective: To determine the impact of anterior knee pain on the QOL among runners in Ekurhuleni, Gauteng. Materials & methods: A cross–sectional study design was used. A population of 73 runners with AKP were included. Participants included runners aged 13 to 55-year-old. The SF-36 questionnaire was used to collect data. Ethical clearance, permission from club managers and consent from participants were obtained. Data were collected over six weeks and analysed using SPSS. Descriptive statistics included frequencies, means, standard deviations and ranges. Inferential statistics included Spearman's correlation calculation. Results: The lowest QOL scores were found among: role functioning/physical (62), role functioning/emotional (59), energy/fatigue (59), emotional well-being (68) and pain scales (63). Males, youth and runners with least experience presented with lowest scores. Significant correlation was found between: role functioning/physical and experience (p =.030; rs =-.221), role functioning/emotional and gender (p =.017; rs =-.247) and race (p =.012; rs =-.265), general health and experience (p =.021; rs =-.239), energy/fatigue and race (p =.012; rs =.264), emotional well-being and age (p =.020; rs =.241), general health and gender (p =.013; rs =.456), social functioning and age (p =.010; rs =.271) and energy/fatigue and experience (p =.001; rs =-.371). Discussion & Conclusion: This study highlights the need to improve QOL among running population with AKP. Multidimensional rehabilitation programmes are recommended.
Key words: anterior knee pain, quality of life, runners