bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Tumor-Immune Response Is Not Compromised by Mesenchymal Stromal Cells in Humanized Mice
Authors: Moquin-Beaudry Gaël , Colas Chloé , Li Yuanyi , Bazin Renée , Guimond Jean V. , Haddad Elie , Beauséjour Christian 
Published: October 2019

Abstract
Therapeutic uses of mesenchymal stromal cells (MSCs) have emerged over the past decade. Yet, their effect on tumor growth remains highly debated, particularly in an immune competent environment. In this study, we wanted to investigate the impact of human umbilical cord–derived MSCs (hUC-MSCs) on tumor growth in humanized mice generated by the human adoptive transfer of PBMCs or the cotransplantation of hematopoietic stem cells and human thymic tissue (human BLT [Hu-BLT]). Our results showed that the growth and immune rejection of engineered human fibroblastic tumors was not altered by the injection of hUC-MSCs in immune-deficient or humanized mice, respectively. This was observed whether tumor cells were injected s.c. or i.v. and independently of the injection route of the hUC-MSCs. Moreover, only in Hu-BLT mice did hUC-MSCs have some effects on the tumor-immune infiltrate, yet without altering tumor growth. These results demonstrate that hUC-MSCs do not promote fibroblastic tumor growth and neither do they prevent tumor infiltration and rejection by immune cells in humanized mice.
On ideal sequence covering maps
Authors: Pal Sudip Kumar , Adhikary Nayan , Samanta Upasana 
Published: October 2019

<p> In this paper we introduce the concept of ideal sequence covering map which is a generalization of sequence covering map, and investigate some of its properties. The present article contributes to the problem of characterization to the certain images of metric spaces which posed by Y. Tanaka [22], in more general form. The entire investigation is performed in the setting of ideal convergence extending the recent results in [11,15,16]. </p>
The early history of the Jicamarca Radio Observatory and the incoherent scatter technique
Authors: Woodman Ronald F. , Farley Donald T. , Balsley Ben B. , Milla Marco A. 
Published: October 2019

Abstract. The purpose of these historical notes is to present the early history of the Jicamarca Radio Observatory (JRO), a research facility that has been conducting observations and studies of the equatorial ionosphere for more than 50 years. We have limited the scope of these notes to the period of the construction of the observatory and roughly the first decade of its operation. Specifically, this period corresponds to the directorships under Kenneth Bowles, Donald Farley, and Tor Hagfors and the first period of Ronald Woodman, i.e., the years between 1960 and 1974. Within this time frame, we will emphasize observational and instrumental developments which led to define the capabilities of the Jicamarca incoherent scatter (IS) radar to measure the different physical parameters of the ionosphere. At the same time, we partially cover the early history of the IS technique which has been used by many other observatories built since. We will also briefly mention the observatory's early and most important contributions to our understanding of the physical mechanisms behind the many peculiar phenomena that occur at the magnetic Equator. Finally, we will put special emphasis on the important developments of the instrument and its observing techniques that frame the capabilities of the radar at that time.
Predictability of non-phase-locked baroclinic tides in the Caribbean Sea
Authors: Zaron Edward D. 
Published: October 2019

Abstract. The predictability of the sea surface height expression of baroclinic tides is examined with 96 h forecasts
produced by the AMSEAS operational forecast model during 2013–2014.
The phase-locked tide, both barotropic and baroclinic, is identified by harmonic analysis of the
2-year record and found to agree well with observations from tide gauges
and satellite altimetry within the Caribbean Sea.
The non-phase-locked baroclinic tide, which is
created by time-variable mesoscale stratification and currents, may be identified from
residual sea level anomalies (SLAs) near the tidal frequencies.
The predictability of the non-phase-locked tide is assessed by measuring the difference
between a forecast – centered at T+36, T+60, or T+84 h – and
the model's later verifying analysis for the same time.
Within the Caribbean Sea, where a baroclinic tidal sea level range of ±5 cm is typical,
the forecast error for the non-phase-locked tidal SLA is correlated with the forecast
error for the subtidal (mesoscale) SLA.
Root mean square values of the former range from 0.5 to
2 cm, while the latter ranges from 1 to 6 cm, for a typical
84 h forecast.
The spatial and temporal variability of the forecast error is related to the
dynamical origins of the non-phase-locked tide and is briefly surveyed
within the model.
Déjà vu
Authors: Feenstra A.A. 
Published: October 2019

Déjà vu
In dit redactioneel worden de nieuwe ATV-richtlijnen voor vervolging van fiscale delicten en douanedelicten van Curaçao besproken. Het valt op dat deze ATV-richtlijnen de ontwikkelingen die hebben geleid tot het huidige AAFD-protocol in Nederland niet hebben gevolgd. Niettemin vormen deze richtlijnen recht in de zin van artikel 79 RO en kan in een strafrechtelijke vervolging om opheldering worden gevraagd als deze richtlijnen niet lijken te zijn gevolgd.
De evenredigheidstoetsing van de Wet Bibob: wie het meerdere mag, mag ook het mindere?
Authors: van der Vorm B. 
Published: October 2019

De evenredigheidstoetsing van de Wet Bibob: wie het meerdere mag, mag ook het mindere?
Door het college van gedeputeerde staten van Groningen is een advies aangevraagd bij het Landelijk Bureau Bibob. Op grond hiervan wordt de omgevingsvergunning verleend voor de duur van vijf jaren. De Afdeling overweegt dat deze vergunningverlening voor de duur van vijf jaren in strijd is met de voorgeschreven evenredigheidstoetsing van artikel 3, vijfde lid, Wet Bibob.
Motivational profiles related to the academic satisfaction of university students
Authors: Vergara-Morales Jorge , Del Valle Milenko , Díaz Alejandro , Matos Lennia , Pérez María-Victoria 
Published: October 2019

Los objetivos del estudio fueron identificar los perfiles motivacionales de estudiantes universitarios y evaluar sus diferencias en cuanto a la satisfacción académica. Los participantes fueron 882 estudiantes con edades comprendidas entre los 17 y 50 años, procedentes de nueve universidades chilenas. Los perfiles motivacionales se identificaron mediante análisis de conglomerados, siguiendo la combinación de métodos jerárquicos y no jerárquicos. El análisis de conglomerados se realizó incluyendo las siguientes variables motivacionales: (1) motivación autónoma, (2) motivación controlada, (3) percepción de apoyo a la autonomía, y (4) percepción de control de la autonomía. Las diferencias entre los perfiles se evaluaron a través de la prueba Anova unifactorial, considerando el cálculo del tamaño del efecto y el análisis post-hoc de Games-Howell. Los resultados del análisis de conglomerados apoyaron una solución de cuatro perfiles motivacionales: mala calidad (n = 167), baja cantidad (n = 144), buena calidad (n = 333), y alta cantidad (n = 238). Además, los estudiantes agrupados en los perfiles con mayores niveles de autonomía para el aprendizaje, presentaron los niveles más altos de satisfacción académica. Como conclusión, se destaca la importancia que tienen los factores motivacionales para facilitar el desarrollo del bienestar de los estudiantes universitarios.
The aims of the study were to identify the motivational profiles of university students and to assess their differences according the academic satisfaction. The participants were 882 students aged 17 to 50, from nine Chilean universities. Motivational profiles were identified by cluster analysis, following the combination of hierarchical and non-hierarchical methods. The cluster analysis was perform including the following motivational variables: (1) autonomous motivation, (2) controlled motivation, (3) perception of autonomy support, and (4) perception of autonomy control. The differences among the profiles were assessed through the one way Anova test, considering the effect size calculation, and the Games-Howell post-hoc analysis. The cluster analysis results supported a four motivational profiles solution: poor quality (n = 167), low quantity (n = 144), good quality (n = 333), and high quantity (n = 238). Moreover, students grouped into profiles with higher levels of autonomy for learning, presented the highest levels of academic satisfaction. In conclusion, the importance of motivational factors to facilitate the development of university students’ well-being is highlighted.
A predictive study of antecedent variables of Passion towards Work
Authors: Serrano-Fernández María-José , Boada-Grau Joan , Gil-Ripoll Carme , Vigil-Colet Andreu 
Published: October 2019

Antecedentes: El objetivo de este estudio fue realizar un estudio correlacional-predictivo de las variables antecedentes de la Pasión por el trabajo. Método: Los participantes han sido 513 trabajadores (48,1 % hombres, 51,9 % mujeres), obtenidos mediante un muestreo no probabilístico. Se han utilizado los programas FACTOR (versión 7.2) y SPSS 20.0. Resultados: se determina la capacidad predictiva de variables como Personalidad, Engagement, Autoeficacia, ICO, Satisfacción por la vida y Estilo de vida sobre la Pasión por el trabajo. Conclusiones: La Pasión por el Trabajo se puede predecir de la siguiente manera: La Pasión Armoniosa de forma directa con las variables Dedicación, Crecimiento, Actividad física, Satisfacción con la vida y Responsabilidad excesiva, y de manera inversa con el Vigor. Mientras que la Pasión Obsesiva a través de las variables Absorción y Responsabilidad excesiva y de manera negativa la Satisfacción con la vida, la Apertura a la experiencia y la Amabilidad.
The aim of this study was to conduct a correlational-predictive study of the antecedent variables of Passion towards Work. The participants were 513 workers (48.1% male, 51.9% female), obtained through non-probability sampling. We used the FACTOR 7.2 and SPSS 22.0. In the results we find that variables such as Personality, Engagement, Self-efficacy, obsessive-compulsive component, Life satisfaction and Lifestyle were predictive of Passion towards Work. In conclusion Passion towards Work can be predicted as follows: The variables Dedication, Growth, Physical activity, Satisfaction with life and Excessive responsibility were direct predictors of Harmonious Passion whereas Vigor was an inverse predictor. Similarly, the variables Absorption and Excessive responsibility were predictors of Obsessive Passion, whereas Satisfaction with life, Openness to experience and Kindness were negative predictors.
Work Ethic: analysis of differences between four generational cohorts
Authors: Zúñiga Diana Carolina , Aguado Garcia David , Rodriguez Barroso Jesus , De Miguel Calvo Jesus Maria 
Published: October 2019

Las organizaciones enfrentan el reto de gestionar una fuerza laboral multigeneracional con características propias que difieren en el valor que le otorgan al trabajo. La incorporación al mercado laboral de las generaciones más jóvenes hace imprescindible el estudio de sus diferentes actitudes hacia el trabajo en comparación con las generaciones antecesoras. El propósito de la investigación fue analizar a través del constructo de la ética protestante las diferencias existentes en las actitudes hacia el trabajo de cuatro generaciones (Baby Boomers, Generación X, Generación Y, y Generación Z).
La muestra de 624 participantes ecuatorianos (BB 11.2%; GX 11.2%, GY 58.5% y GZ 19.1%) se agrupó por cohortes. Se aplicó el Cuestionario Multidimensional Ética del Trabajo (MWEP). Los resultados mostraron que los BB y la GX tiene una mayor creencia en la importancia del trabajo y más tolerancia a la utilización improductiva del tiempo de trabajo que las generaciones Y y Z. En el aplazamiento de las recompensas la GZ muestra puntuaciones superiores a las obtenidas por los BB, GX y GY. No se encuentran diferencias significativas en las dimensiones de autoconfianza, ocio y moralidad-ética.
Enterprises face the challenge of managing a multigenerational workforce which has its characteristics that differ in the value they grant to work. Incorporation of younger generations into the labour market requires to study all their attitudes towards work, contrasting them with previous generations. The purpose of this research was to analyse, through the Protestant Ethic construct, the differences of four age groups in attitudes towards work (Baby Boomers, Generation X, Generation Y, and Generation Z).
Cohorts grouped the sample of 624 Ecuadorians (BB 11.2%; Gen X 11.2%, Gen Y 58.5% and Gen Z 19.1%). The Multidimensional Work Ethic Profile (MWEP) was applied. The results showed that BB and Gen X believe more in the importance of work than generations Y and Z. At the same time, BB and Gen X are more tolerant to the unproductive use of time than generations Y and Z. Gen Z has higher scores than BB, Gen X and Gen Y in the postponement of rewards dimension. Besides, there are no meaningful differences in self-reliance, leisure and morality/ethics dimensions.
Influence of personality variables, impulsivity, perfectionism, self-esteem and self-efficacy in Work Craving
Authors: Serrano-Fernández María-José , Boada-Grau Joan , Assens-Serra Jordi , Boada-Cuerva Maria , Vigil-Colet Andreu 
Published: October 2019

Antecedentes: Estudios recientes has sugerido que hay relación entre algunas variables de personalidad y la adicción al trabajo. En el presente trabajo nos hemos planteado el objetivo de realizar un estudio Predictivo de las variables antecedentes del Work Craving a través de las variables Impulsividad, Personalidad, Perfeccionismo, autoestima y Autoeficacia. Método: Los participantes han sido 332 trabajadores, obtenidos mediante un muestreo no probabilístico. Se han utilizado los programas FACTOR (versión 7.2) y SPSS 23.0. Resultados: se determina la capacidad predictiva de variables de personalidad y autoestima sobre el Work Craving. Conclusiones: El Work Craving se puede predecir a través de determinadas variables (Estabilidad emocional, Perfeccionismo y autoestima), contribuyendo la presente investigación a un mayor conocimiento de la Adicción al Trabajo y a la potenciación de un estilo de vida saludable que se puede ver afectado por la Adicción al Trabajo.
Background: Recent studies have suggested a relationship between certain personality variables and work addiction. In the present work we conduct a predictive study of the background variables of work craving through the variables Impulsivity, Personality, Perfectionism, Self-esteem and Self-efficacy. Method: The participants were 332 workers obtained by non-probability sampling. We used the FACTOR programs (version 7.2) and SPSS 23.0. Results: The predictive capacity of personality variables and self-esteem is determined on the work craving. Conclusions: Work craving can be predicted through certain variables (Emotional Stability, Perfectionism and Self-esteem). This research contributes to greater knowledge of work addiction and to the empowerment of a healthy lifestyle that can be affected by addiction to work. No funding has been received to make this article.
Sobre Dewey, jogos digitais e ensino de História
Authors: Pedrosa Stella Maria Peixoto de Azevedo , Soares Kauan Pessanha 
Published: October 2019

O artigo associa a filosofia progressista de John Dewey, talvez o mais influente filósofo da educação no século XX, às concepções de jogos digitais e ao processo ensino-aprendizagem da História, considerando o jogo como uma possibilidade para o ensino dos conteúdos curriculares desta disciplina. Dewey defendeu a afinidade de todo conhecimento com o conhecimento prévio e, em termos historicistas, via a disciplina História como um produto do desenvolvimento histórico. Em sua perspectiva, para a compreensão de qualquer porção do conhecimento e sua relação com um indivíduo ou sociedade, deve-se entender sua história e, nesse sentido, considera o currículo organizado como uma história reencenada e cuidadosamente selecionada. Deste modo, os jogos digitais podem contribuir para o ensino dos conteúdos curriculares de História, visto que muitas de suas temáticas envolvem, de forma lúdica, importantes fatos históricos da humanidade, proporcionando o contato e ampliando o interesse pelo conhecimento histórico. Sob o enfoque deweyano, buscando-se integrar a “vida real” com as atividades escolares, discute-se de que modo os jogos digitais podem colaborar para que suas narrativas sejam relacionadas ao processo de ensino-aprendizagem. Em síntese, no artigo a perspectiva de Dewey é relacionada às concepções de jogos digitais e ao ensino da História, sendo, o jogo apresentado como uma possibilidade para a aprendizagem da História.
Ensino de dança na escola: desafios e perspectivas na visão de professores
Authors: Batalha Cecília Silvano , Cruz Giseli Barreto da 
Published: October 2019

O presente estudo trata de uma pesquisa, desenvolvida no Estado do Rio de Janeiro, cujo objetivo consistiu em compreender como professores com formação superior em dança, que atuaram ou estão atuando na educação básica, no contexto da escola pública, concebem o ensino de dança e, além disso, o que fazem (se fazem) a favor da sua inserção enquanto área de conhecimento no currículo escolar. A abordagem se atém a parte dos resultados obtidos, detendo-se especificamente nos aspectos referentes à inserção da dança no currículo escolar, considerando quatro eixos analíticos: i - produção do conhecimento por meio do corpo; ii - possibilidade de trabalhar questões sociais e humanas; iii - questões multiculturais presentes na inserção da dança no currículo; iv - dificuldades estruturais para o ensino de dança na escola. O referencial teórico baseia-se em Cochran-Smith e Lytle (1999; 2002), Gauthier (2006) e Schön (2000); Canen/Ivenicki (2012; 2014); Marques (2010a; 2011; 2012); Strazzacappa (2010); Strazzacappa e Morandi (2012). Metodologicamente, adota-se a análise documental e a entrevista semiestruturada. Os resultados da pesquisa indicam que a inserção da dança no currículo é um desafio evidente para os professores, ainda que se reconheça que este ensino possa ser um espaço potente para a produção do conhecimento por meio do corpo, possibilitando uma formação mais abrangente.
Rede social e comunicação ubíqua: o que podemos aprender com Black Mirror?
Authors: Couto Junior Dilton Ribeiro , Santos Rosemary dos , Velloso Luciana 
Published: October 2019

Este texto busca tecer reflexões em torno de práticas sociais mediadas pelo digital em rede retratadas no episódio intitulado Queda Livre da série Black Mirror. A proposta é discutir a relação entre interconectividade, popularidade e visibilidade na era da comunicação ubíqua com a intenção de ressignificar nossa própria experiência humana, que vem sendo cada vez mais mediada pelos processos comunicacionais digitais. Buscar inspiração na ficção de Black Mirror pode se constituir como um caminho potente para refletirmos sobre nossa humanização numa era marcada pela intensa produção e compartilhamento de dados entre usuárias/os geograficamente dispersas/os. Para além do caráter ficcional da série e das situações expressas no episódio, há ali um alerta para os extremos a que o uso dos dispositivos digitais pode nos levar, fazendo-nos refletir sobre a importância de se colocar em prática uma educação que amplie nossa visão sobre o potencial da interconectividade e seus desdobramentos. Que esses novos fenômenos ciberculturais nos permitam tecer reflexões profícuas para uma melhor compreensão das práticas sociais contemporâneas, pelas relações que vimos estabelecendo com as redes sociais, com a emergência da comunicação ubíqua e com a ressignificacão de novas experiências sociais que emergem atravessadas pelo digital em rede na vida cotidiana.
Demographics and Pattern of Ocular Diseases in Patients with Chronic Kidney Disease at the University of Port Harcourt Teaching Hospital
Authors: O. Aliu Rachael , Awoyesuku Elizabeth A. , Pedro-Egbe Chinyere N. 
Published: October 2019

Aims: To determine the demographics and pattern of ocular diseases in patients with Chronic Kidney Disease at the University of Port Harcourt Teaching Hospital.
Study Design: This was a hospital-based cross-sectional study.
Place and Duration of Study: This study was carried out at the Dialysis clinic of the University of Port Harcourt Teaching Hospital, Rivers State, Nigeria from February 2013 to February 2014.
Methodology: The Sample size was estimated to be 85 adult patients and cconsecutive adult patients with chronic renal failure who are having haemodialysis were enrolled into the study. The patients who met the inclusion criteria were randomly booked at the Dialysis Clinic and had no prior knowledge of the study; hence there was no bias in case selection. Ethical approval was obtained from the institutions ethical committee. Each participant had a comprehensive ocular examination including fundus photography. Subjects needing further evaluation and treatment were referred to the Eye Clinic of the Ophthalmology Department of the University of Port Harcourt Teaching Hospital, Port Harcourt.
Results: A total of 170 eyes of 85 persons were examined in this study (100% coverage). A total of 30 (35.4%) females and 55 (64.6%) males were examined giving a male to female ratio of 1.8:1.
Approximately half of the study subjects (54.1%) had no previous eye problem prior to developing chronic renal failure while about a quarter (n= 20, 23.5%) had refractive error and difficulty in reading near prints .After diagnosis of chronic kidney disease however a total of 40 (47%) of study subjects had visual impairment while 2(2.4%) were blind and 43(50.6%) of the study population however had normal vision.
Conclusion: Chronic Kidney disease is an important cause of ocular morbidity in our environment with majority of those affected being males in the third to fifth decades of life. Posterior segment disorders were the commonest disorders seen.
Seed‐Induced Vertical Growth of 2D Bi2O2Se Nanoplates by Chemical Vapor Transport
Authors: Wu Zhen , Liu Guoliang , Wang Yuxi , Yang Xin , Wei Tianqi , Wang Qianjin , Liang Jie , Xu Ning , Li Zizhong , Zhu Bin , Qi Heshan , Deng Yu , Zhu Jia 
Published: October 2019

AbstractAs two‐dimensional (2D) layered materials attract more attention owing to their unique optical, electrical, and thermal properties, there are persistent efforts to grow high‐quality 2D layered materials for fundamental research and device applications. While large‐area 2D layered materials with high crystal quality can be obtained through chemical vapor transport, the strong binding between 2D layered materials and substrates poses a significant challenge for attempts to reveal their intrinsic properties and to use these 2D building blocks for constructing advanced heterostructured devices. Therefore, it would be ideal to grow high‐quality 2D materials with minimized contact and binding with substrate. Through both calculation and experiment, it is demonstrated that by introducing a seed layer at the nucleation stage, the crystallographic disregistry and the corresponding adhesion energy between 2D materials and substrate can be altered, resulting in a change of crystal surface in contact with the substrate, and therefore vertical growth of 2D materials on substrates. As an example, it is demonstrated that with Bi2O3 serving as a seed layer, vertical growth of 2D plates of Bi2O2Se on mica substrates can be realized. These vertically grown 2D nanoplates of Bi2O2Se can be conveniently transferred with their thermal properties investigated for the first time.