bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan antara kadar procalcitonin dengan kriteria Anthonisen pada PPOK eksaserbasi akut
Authors: Megasari Ariska , Rai Ida Bagus Ngurah , Suryana Ketut 
Published: September 2019

Background: COPD exacerbations can be caused by infections and environmental pollutants. One guideline for antibiotic administration in acute exacerbation COPD is in patients with Anthonisen criteria types 1 and 2 based on patients' subjective complaints (increased dyspneu, increased sputum volume and sputum purulence). Procalcitonin (PCT) is an objective and specific marker of bacterial infections that are not affected much by disease condition or steroid drugs that are widely used by COPD patients. This study was conducted to determine the relationship between procalcitonin levels and Anthonisen criteria in acute exacerbation of COPD.
Methods: This study used an analytical cross sectional design at Sanglah General Hospital and Wangaya Hospital in March-May 2018. Data analysis used the Bivariate Spearman correlation test, and Kruskal-wallis to determine the median PCT level difference according to Anthonisen type.
Result: Total subjects were 43 samples of acute exacerbation COPD patients, with median PCT levels were 0.18 (0.02-47.8) ng/ml. Spearman correlation analysis showed no significant correlation between serum PCT levels and Anthonisen type (r = -0,175, p = 0.26). We also found a significant correlation between Anthonisen criteria with WBC and neutrophil count. After excluding several outliers data, there was a significant difference in median PCT value based on the Anthonisen type. The median PCT was higher in Anthonisen type 1 compared to type 2 and 3 (p = 0.029).
Conclusion: there was no relationship between levels of PCT with Anthonisen type but we found significant higher PCT level in Anthonisen type 1 after excluding extreme value.
Hubungan Radioterapi dengan Kejadian Depresi pada Pasien Lansia dengan Kanker Kepala Leher
Authors: Sekarnegari Gendis 
Published: September 2019

Latar belakang : Laju pertumbuhan penduduk usia lanjut mengalami peningkatan yang konstan terutama di negara-negara berkembang. Pertumbuhan ini diiringi dengan prevalensi penyakit yang meningkat, salah satunya kanker kepala dan leher. Radioterapi yang merupakan modalitas utama kanker kepala dan leher dapat memberikan efek yang buruk bagi keadaan psikososial pasien, termasuk depresi. Penelitian ini bertujuan untuk mengukur hubungan antara radioterapi dengan skor Geriatric Depression Scale (GDS) pada dua kelompok sampel; pasien yang belum dan sedang menjalani radioterapi. Metode : Penelitian ini menggunakan desain cross-sectional pada 28 pasien usia lanjut dengan kanker kepala dan leher di Instalasi Radioterapi RSUP Dr. Kariadi Semarang sejak bulan April hingga Agustus 2015. Karakteristik sosiodemografis dan data klinis yang mencakup diagnosis kanker, stadium dan frekuensi radioterapi adalah data sekunder yang diambil dari catatan medik, diikuti oleh wawancara berbasis kuesioner. Analisis statistik menggunakan Independent T-test dan uji korelasi Pearson. Hasil : Rerata total skor GDS berbeda secara signifikan pada pasien yang belum menjalani terapi dan pada pasien yang sedang menjalani terapi dengan skor masing-masing 2,64 dan 6,64 (p=0,01). Terdapat hubungan signifikan positif kuat antara radioterapi dengan kejadian depresi (p=0,006, r=0,507). Stadium kanker memiliki korelasi yang sangat lemah terhadap skor GDS (r=0,141) Simpulan : Terdapat hubungan antara kejadian depresi dengan paparan terhadap radioterapi pada pasien usia lanjut dengan kanker kepala dan leher
Pengembangan Modul Mata Kuliah Strategi Belajar dan Pembelajaran Pada FKIP-Universitas Baturaja
Authors: Agustina Nora , Adesti Anita 
Published: September 2019

Tujuan dari penelitian ini adalah untuk mengembangkan modul pembelajaran yang valid dan praktis pada mata kuliah Strategi belajar dan pembelajaran pada Program Studi Teknologi Pendidikan FKIP Universitas Baturaja. Metode penelitian menggunakan Metode Pengembangan dengan model desain pengembangan produk Rowntree. Pengumpulan data dilakukan melalui (1) uji para ahli (expert) meliputi uji ahli media, ahli desain dan ahli materi, kemudian (2) uji Lapangan meliputi: uji perorangan (one to one), uji kelompok kecil (Small Group) dan Uji Lapangan (field tes), Subjek penelitian terdiri dari 20 orang responden. Berdasarkan hasil penelitian telah dihasilkan pengembangan modul pada mata kuliah Strategi Belajar dan Pembelajaran yang teruji validitasnya. Pengembangan modul yang dihasilkan dari aspek Materi sudah tepat dengan pembelajaran, menggunakan media cetak, gambar yang tepat, dan jelas dalam uraian materi, soal latihan dan soal evaluasi. Dari aspek Desain pembelajaran, Pengembangan modul yang dihasilkan memiliki kesesuaian pendekatan dalam pembelajaran, efektif dan efisien dalam pencapaian kompetensi, sesuai dengan karakteristik sasaran, soal latihan dan soal evaluasi sesuai dengan RPS. Dari aspek Media modul yang dihasilkan memiliki kemenarikan dan kemudahan dalam memahami materi sehingga diharapkan dapat mendorong mahasiswa untuk lebih termotivasi dalam belajar. Jadi dapat disimpulkan bahwa perkuliahan pada mata kuliah Strategi Belajar dan Pembelajaran menggunakan modul dapat meningkatkan aktivitas belajar mahasiswa.
Kata kunci : Pengembangan, Modul Pembelajaran, Strategi Belajar dan Pembelajaran
Over de Tiffany/Swatch-procedures en het Nederlandse materiële recht bezien vanuit internationale partijen
Authors: Luycks J.M. , Hendrikx A.M.M. 
Published: September 2019

Over de Tiffany/Swatch-procedures en het Nederlandse materiële recht bezien vanuit internationale partijen
Deze bijdrage bevat een beschouwing naar aanleiding van de arbitrage en vernietigingsprocedure tussen Tiffany en Swatch. Het Nederlandse materiële recht bezien vanuit internationale partijen staat centraal, waarbij de focus ligt op het onderscheid tussen de uitleg en aanvulling van een overeenkomst en de gevolgen van een door partijen gemaakte rechtskeuze.
Herziening consumentenrechten: verkenning van Richtlijn 2019/771
Authors: Spanjaard J.H.M. 
Published: September 2019

Herziening consumentenrechten: verkenning van Richtlijn 2019/771
Op 20 mei 2019 werd de Richtlijn Consumentenkoop aangenomen. Deze richtlijn gaat invloed hebben op de wettelijke regeling over conformiteit bij consumentenkoop. De richtlijn voorziet in een eigen conformiteitsregel en een eigen toepassingsbereik. In deze bijdrage wordt de richtlijn verkend en de invloed op de bestaande regeling besproken.
Nanotherapy in Joints: Increasing Endogenous Hyaluronan Production by Delivering Hyaluronan Synthase 2
Authors: Li Huimin , Guo Huilin , Lei Chang , Liu Li , Xu Liqin , Feng Yaping , Ke Jin , Fang Wei , Song Hao , Xu Chun , Yu Chengzhong , Long Xing 
Published: September 2019

AbstractOsteoarthritis (OA) is a common joint degenerative disease that causes pain, joint damage, and dysfunction. External hyaluronic acid (HA) supplement is a common method for the management of osteoarthritis which requires multi‐injections. It is demonstrated that biodegradable mesoporous silica nanoparticles successfully deliver an enzyme, hyaluronan synthase type 2 (HAS2), into synoviocytes from the temporomandibular joint (TMJ) and generate endogenous HA with high molecular weights. In a rat TMJ osteoarthritis inflammation model, this strategy promotes endogenous HA production and inhibits the synovial inflammation of OA for more than 3 weeks with one‐shot administration. Such nanotherapy also helps repairing the bone defects in a rat OA bone defect model.
Recent Advanced Materials for Electrochemical and Photoelectrochemical Synthesis of Ammonia from Dinitrogen: One Step Closer to a Sustainable Energy Future
Authors: Yan Zihao , Ji Mengxia , Xia Jiexiang , Zhu Huiyuan 
Published: September 2019

AbstractAmmonia (NH3), an important raw material for chemical industry and agriculture, is also considered to be an intriguing energy storage and transportation media for chemical conversion schemes. The world's primary NH3 supply is based on the natural nitrogen fixation by diazotrophs through an enzymatic nitrogenase process and the industrial nitrogen fixation through a traditional Haber–Bosch process. The natural synthesis of NH3 can hardly meet the rapidly growing global demand. Meanwhile, the industrial NH3 production is still dominated by the high‐temperature and high‐pressure reaction between nitrogen and hydrogen (N2 + 3H2 → 2NH3), requiring intensive energy input and generating massive CO2. Therefore, seeking a breakthrough in the development of catalysts toward efficient ammonia synthesis has become the frontier of energy and chemical conversion schemes. This review summarizes and discusses the recent progress on developing new strategies to optimize the efficiency of NH3 production coupled with renewable energy sources, with a specific focus on electrocatalytic and photoelectrocatalytic conversion of N2 to NH3. The most recent advances in the development of catalytic materials, the design of the reaction systems, and the computational insights for electrochemical and photoelectrochemical ammonia synthesis are covered.
Aqueous‐Phase Oxidation of N‐Substituted N‐PhosphonomethylGlycines into Glyphosate with Hydrogen Peroxide in the Presence of Carbon‐Supported Gold Catalysts
Authors: Pyrjaev Pavel A. , Yushchenko Dmitry Yu. , Moroz Boris L. , Pai Zinaida P. , Bukhtiyarov Valerii I. 
Published: September 2019

AbstractThe catalytic performance of carbon‐supported gold nanoparticles has been studied for the oxidative dealkylation of a series of N‐substituted N‐phosphonomethyl glycines into N‐phosphonomethyl glycine (“glyphosate”) using dilute (0.11 m) aqueous H2O2 solution as oxidant. It was shown that the electron‐donating inductive (+I) effect of the hydrocarbon substituent at the nitrogen atom greatly influences both the substrate reactivity and product distribution. Gold nanoparticles of 1.5‐2.5 nm in diameter synthesized by “cationic adsorption” technique on the mesoporous Sibunit carbons, which are pre‐oxidized with HNO3 and containing a lot of surface acidic groups, were found to catalyze the formation of glyphosate from N‐isopropyl‐N‐phosphonomethyl glycine at 70 °C with selectivity up to 94% at 98% substrate conversion. Oxidation of other substrates containing the substituents with a weaker +I effect than that of iPr group resulted a large amount of undesirable N‐decarboxymethylation product in addition to glyphosate. Considering the literature data and our own experimental results, assumptions about the reaction mechanism and causes of the observed trends are made.
Potential and Limitations in Estimating Sensible-Heat-Flux Profiles from Consecutive Temperature Profiles Using Remotely-Piloted Aircraft Systems
Authors: Båserud Line , Reuder Joachim , Jonassen Marius O. , Bonin Timothy A. , Chilson Phillip B. , Jiménez Maria A. , Durand Pierre 
Published: September 2019

Abstract
Profiles of the sensible heat flux are key to understanding atmospheric-boundary-layer (ABL) structure and development. Based on temperature profiling by a remotely-piloted aircraft system (RPAS), the Small Unmanned Meteorological Observer (SUMO) platform, during the Boundary Layer Late Afternoon and Sunset Turbulence (BLLAST) field campaign, 108 heat-flux profiles are estimated using a simplified version of the prognostic equation for potential temperature $$\theta $$θ that relates the tendency in $$\theta $$θ to the flux divergence over the time span between two consecutive flights. We validate for the first time RPAS-based heat-flux profiles against a network of 12 ground-based eddy-covariance stations (2–60 m above ground), in addition to a comparison with fluxes from a manned aircraft and a tethered balloon, enabling the detailed investigation of the potential and limitations related to this technique for obtaining fluxes from RPAS platforms. We find that appropriate treatment of horizontal advection is crucial for obtaining realistic flux values, and present correction methods specific to the state of the ABL. Advection from a mesoscale model is also tested as another correction method. The SUMO heat-flux estimates with appropriate corrections compare well with the reference measurements, with differences in the performance depending on the time of day, since the evening period shows the best results (94$$\%$$% within the spread of ground stations), and the afternoon period shows the poorest results (63$$\%$$% within the spread). The diurnal cycle of the heat flux is captured by the SUMO platform for several days, with the flux values from the manned aircraft and tethered balloon coinciding well with those from the SUMO platform.
Central configurations in planar n-body problem with equal masses for $$n=5,6,7$$
Authors: Moczurad Małgorzata , Zgliczyński Piotr 
Published: September 2019

Abstract
We give a computer-assisted proof of the full listing of central configuration for n-body problem for Newtonian potential on the plane for $$n=5,6,7$$

n
=
5
,
6
,
7

with equal masses. We show all these central configurations have a reflective symmetry with respect to some line. For $$n=8,9,10$$

n
=
8
,
9
,
10

, we establish the existence of central configurations without any reflectional symmetry.
Resolvent Decomposition Theorems and Their Application in Denumerable Markov Processes with Instantaneous States
Authors: Chen Anyue 
Published: September 2019

Abstract
The basic aim of this paper is to provide a fundamental tool, the resolvent decomposition theorem, in the construction theory of denumerable Markov processes. We present a detailed analytic proof of this extremely useful tool and explain its clear probabilistic interpretation. We then apply this tool to investigate the basic problems of existence and uniqueness criteria for denumerable Markov processes with instantaneous states to which few results have been obtained even until now. Although the complete answers regarding these existence and uniqueness criteria will be given in a subsequent paper, we shall, in this paper, present part solutions of these very important problems that are closely linked with the subtle Williams S and N conditions.
Distinguishing between basic psychological needs and basic wellness enhancers: the case of beneficence as a candidate psychological need
Authors: Martela Frank , Ryan Richard M. 
Published: September 2019

AbstractIn order to be considered a basic psychological need, a candidate need should fulfill several criteria, including need satisfaction having a unique positive effect on well-being, and need frustration having a unique effect on ill-being, properties demonstrated by autonomy, competence and relatedness. Previous research has demonstrated that beneficence satisfaction—the sense of having a positive impact on other people—can have a unique positive effect on well-being. In the present study, we examined whether beneficence frustration—the sense of having a negative impact on other people—would be uniquely connected to ill-being. In the first study (N = 332;Mage = 38) we developed a scale to assess beneficence frustration. Then, in two subsequent cross-sectional studies (N = 444 and N = 426;Mage = 38/36) beneficence frustration is correlated with indicators of ill-being (negative affect, depression, anxiety, physical symptoms), but this connection disappears when controlling for the effects of autonomy, competence and relatedness need frustrations. The three needs fully mediate relations between beneficence frustration and all assessed well-being and ill-being indicators in both studies. This leads us to suggest a distinction between basic psychological needs and basic wellness enhancers, the satisfaction of which may improve well-being, but the neglect or frustration of which might not uniquely impact ill-being.
Comparison of quantum cascade structures for detection of nitric oxide at ~ 5.2 μm
Authors: Kolek Andrzej , Hałdaś Grzegorz , Bugajski Maciej 
Published: September 2019

Abstract
Nonequilibrium Green’s function method is used to calculate electronic and optical characteristics of various quantum cascade structures emitting light at ~ 5.2 μm wavelength. Basing on these simulations, the choice of optimal design can be done.
OsbHLH058 and OsbHLH059 transcription factors positively regulate iron deficiency responses in rice
Authors: Kobayashi Takanori , Ozu Asami , Kobayashi Subaru , An Gynheung , Jeon Jong-Seong , Nishizawa Naoko K. 
Published: September 2019

Abstract

Key message
Subgroup IVc basic helix-loop-helix transcription factors OsbHLH058 and OsbHLH059 positively regulate major iron deficiency responses in rice in a similar but distinct manner, putatively under partial control by OsHRZs.

Abstract
Under low iron availability, plants transcriptionally induce the expression of genes involved in iron uptake and translocation. OsHRZ1 and OsHRZ2 ubiquitin ligases negatively regulate this iron deficiency response in rice. The basic helix-loop-helix (bHLH) transcription factor OsbHLH060 interacts with OsHRZ1, and positively regulates iron deficiency-inducible genes. However, the functions of three other subgroup IVc bHLH transcription factors in rice, OsbHLH057, OsbHLH058, and OsbHLH059, have not yet been characterized. In the present study, we investigated the functions of OsbHLH058 and OsbHLH059 related to iron deficiency response. OsbHLH058 expression was repressed under iron deficiency, whereas the expression of OsbHLH057 and OsbHLH060 was moderately induced. Yeast two-hybrid analysis indicated that OsbHLH058 interacts with OsHRZ1 and OsHRZ2 more strongly than OsbHLH060, whereas OsbHLH059 showed no interaction. An in vitro ubiquitination assay detected no OsbHLH058 and OsbHLH060 ubiquitination by OsHRZ1 and OsHRZ2. Transgenic rice lines overexpressing OsbHLH058 showed tolerance for iron deficiency and higher iron concentration in seeds. These lines also showed enhanced expression of many iron deficiency-inducible genes involved in iron uptake and translocation under iron-sufficient conditions. Conversely, OsbHLH058 knockdown lines showed susceptibility to iron deficiency and reduced expression of many iron deficiency-inducible genes. OsbHLH059 knockdown lines were also susceptible to iron deficiency, and formed characteristic brownish regions in iron-deficient new leaves. OsbHLH059 knockdown lines also showed reduced expression of many iron deficiency-inducible genes. These results indicate that OsbHLH058 and OsbHLH059 positively regulate major iron deficiency responses in a similar but distinct manner, and that this function may be partially controlled by OsHRZs.
The German value of time and value of reliability study: the survey work
Authors: Dubernet Ilka , Axhausen Kay W. 
Published: September 2019

AbstractIn 2012 Germany’s Federal Ministry of Transport and Digital Infrastructure (BMVI) initiated several projects in preparation of the new Federal Transport Infrastructure Plan (BVWP) 2030. This included an update of the general methodology and in particular of its cost–benefit analysis which is used to evaluate the effects of hundreds of German infrastructure projects under study. As part of the work the first official values of time (VOT) and values of reliability (VOR) for personal and business travel for Germany derived from a stated preference survey were estimated. From May 2012 until January 2013 nationwide data of more than 3000 participants was collected in a combined two-stage revealed and stated preference survey. This paper discusses the survey design, reports experience of the field phase and analyses the response behaviour of the sample. The stated choice experiments address mode, route, time of departure, workplace and residential location choice. The complex multi-attribute experiments of different types cover various aspects of short and long-term travel choice attributes which the respondent has to take into consideration during his decision process. Furthermore overlapping variables of the stated and revealed preference experiments enabled a joint estimation of the whole data for deriving the VOTs and VORs. Additionally numerous socio-demographic and attitudinal questions plus the large sample size for business and non-business trips make it a unique dataset offering various aspects of travel behaviour and their valuations to explore.
Just about managing: dealing with the threats to industrial systems
Authors: Barda Ilan 
Published: September 2019

Although studies and surveys from analyst firms Gartner and IDC differ slightly, there is an assumption that organisations spend around 10% of their IT budgets on cyber security. 1, 2 When differentiated by industry sector, financial services tend to spend more, leisure and hospitality slightly less. Industrial sectors including manufacturers that deploy industrial control system (ICS) solutions sit somewhere in the middle but often face a set of cyber security challenges that are harder to overcome. This includes budgets for upgrades often measured in five- to 10-year cycles that impose a major obstacle in the fast-changing world of IT-related security. Industrial firms face some particularly difficult cyber security challenges. These include upgrades often measured in five- to 10-year cycles. Many manufacturers that have operated within closed networks have failed to adapt to targeted threats. Underfunding of cyber security along with archaic security principles that lag 10 years behind the mainstream computing world can make industrial organisations easy targets. Firms need to look at holistic solutions that include people, skills and technologies across the organisation, says Ilan Barda of Radiflow.
CATSLife: A Study of Lifespan Behavioral Development and Cognitive Functioning
Authors: Wadsworth Sally J. , Corley Robin P. , Munoz Elizabeth , Trubenstein B. Paige , Knaap Elijah , DeFries John C. , Plomin Robert , Reynolds Chandra A. ,   The CATSLife Team
Published: September 2019

AbstractThe purpose of this update is to provide the most current information about both the Colorado Adoption Project (CAP) and the Longitudinal Twin Study (LTS) and to introduce the Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife), a product of their merger and a unique study of lifespan behavioral development and cognitive aging. The primary objective of CATSLife is to assess the unique saliency of early childhood genetic and environmental factors to adult cognitive maintenance and change, as well as proximal influences and innovations that emerge across development. CATSLife is currently assessing up to 1600 individuals on the cusp of middle age, targeting those between 30 and 40 years of age. The ongoing CATSLife data collection is described as well as the longitudinal data available from the earlier CAP and LTS assessments. We illustrate CATSLife via current projects and publications, highlighting the measurement of genetic, biochemical, social, sociodemographic and environmental indices, including geospatial features, and their impact on cognitive maintenance in middle adulthood. CATSLife provides an unparalleled opportunity to assess prospectively the etiologies of cognitive change and test the saliency of early childhood versus proximal influences on the genesis of cognitive decline.