bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review
Authors: Álvarez-Martínez Francisco Javier , Barrajón-Catalán Enrique , Encinar José Antonio , Rodríguez-Díaz Juan Carlos , Micol Vicente 
Published: October 2018

Background:Multi-drug-resistant bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSA) disseminate rapidly amongst patients in healthcare facilities and suppose an increasingly important cause of community-associated infections and associated mortality. The development of effective therapeutic options against resistant bacteria is a public health priority. Plant polyphenols are structurally diverse compounds that have been used for centuries for medicinal purposes, including infections treatment and possess, not only antimicrobial activity, but also antioxidant, anti-inflammatory and anticancer activities among others. Based on the existing evidence on the polyphenols’ antibacterial capacity, polyphenols may be postulated as an alternative or complementary therapy for infectious diseases.Objective:To review the antimicrobial activity of plant polyphenols against Gram-positive bacteria, especially against S. aureus and its resistant strains. Determine the main bacterial molecular targets of polyphenols and their potential mechanism of action.Methodology:The most relevant reports on plant polyphenols’ antibacterial activity and their putative molecular targets were studied. We also performed virtual screening of thousand different polyphenols against proteins involved in the peptidoglycan biosynthesis to find potential valuable bioactive compounds. The bibliographic information used in this review was obtained from MEDLINE via PubMed.Results:Several polyphenols: phenolic acids, flavonoids (especially flavonols), tannins, lignans, stilbenes and combinations of these in botanical mixtures, have exhibited significant antibacterial activity against resistant and non-resistant Gram-positive bacteria at low μg/mL range MIC values. Their mechanism of action is quite diverse, targeting cell wall, lipid membrane, membrane receptors and ion channels, bacteria metabolites and biofilm formation. Synergic effects were also demonstrated for some combinations of polyphenols and antibiotics.Conclusion:Plant polyphenols mean a promising source of antibacterial agents, either alone or in combination with existing antibiotics, for the development of new antibiotic therapies.
Electrocardiogram Fiducial Points Detection and Estimation Methodology for Automatic Diagnose
Authors: Yáñez de la Rivera René , Soto-Bajo Moisés , Fraguela-Collar Andrés 
Published: October 2018

Background:The estimation of fiducial points is specially important in the analysis and automatic diagnose of Electrocardiographic (ECG) signals.Objective:A new algorithm which could be easily implemented is presented to accomplish this task.Methods:Its methodology is rather simple, and starts from some ideas available in the literature combined with new approachs provided by the authors. First, aQRScomplex detection algorithm is presented based on the computation of energy maxima in ECG signals which allow the measurement of cardiac frequency (in beats per minute) and the estimation of R peaks temporal positions (in number of samples). From these ones, an estimation of fiducial points Q, S, J, P and T waves onset and offset points are worked out, supported in a simple modified slope method with constraints.The location process of fiducial points is assisted with the help of the so called curvature filters, which allow to improve the accuracy in this task.Results:The procedure is simulated in Matlab and GNU Octave by using test signals from the MIT medical database, Cardiosim II equipment patterns and synthetic signals developed by the authors.Conclusion:One of the novelties of this work is the global strategy. Also, another significant innovation is the introduction of the curvature filters. We think this concept will prove to be a useful tool in signal processing, not only in ECG analysis.
NAVAL HYGIENIST PROFESSOR I. V. PETREEV (SCIENTIFIC AND HISTORICAL REVIEW IN VIEW OF 55TH ANNIVERSARY OF THE BIRTH)
Authors: Grebenkov S. V. 
Published: October 2018

Scientific and historical reviewis dedicated to naval hygienist, head of a Department of Naval and Radiation Hygiene (2006–2013) in Military Medical Academy named after S. M. Kirov, holder of Habilitation degree in Medicine, professor Igor Vitalievich Petreev who turned 55 years. He has been working in Military Medical Academy for over 25 years. His contribution to the development of hygieology is that he formed a concept of multi-level optimization of hygienic quality forming for military personnel (2007) in the habilitational thesis. Also here viewed and explainedlist and types of advanced means intended on prevention of world ocean waters pollution from naval ships and vessels (1995). In addition he was initiator and co-author of two-volume guidance on naval and radiation hygiene, multimedia reference-training program «Environmental and health basics of health protection in military» (2001, 2002, 2007) and more than 20 guides. Also he co-authored biography monographs «Notebook of naval hygienists» (2012), «The first Russian Department of hygiene» (2015) and set of articles round the history of a Department of Naval and Radiation Hygiene. His military history sheet states only 2 home stations: Pacific Fleet — chief medical officer of submarine from 1988 to 1992 (Bolshoi Kamen and Petropavlovsk-Kamchatsky-53) and Military Medical Academy named after S. M. Kirov (Leningrad, Saint-Petersburg) — cadet (1982), adjunct (1992), lecturer (1995), as sistant professor (2003), chief of a department (2006), head of a department (2011) of Naval and Radiation Hygiene, since 2013 — professor of a Department (of common and military hygiene with the course of naval and radiation hygiene). Military service of professor I. V. Petreev ended in 2011 when the only one in the country Department of Naval and Radiation Hygiene became civil. After demobilization Igor Vitalievich teaches in Military Medical Academy to the present day.
CONCEPTUAL APPROACHES TO DEVELOPMENT OF MARINE MEDICINE IN ATLANTIC REGIONAL DIRECTION OF NATIONAL NAVAL POLICY OF THE RUSSIAN FEDERATION
Authors: Mosyagin I. G. , Boyko I. M. 
Published: October 2018

The paper represents fundamental principles of concept of development of naval medicine in one of six main regional directions of national naval policy of the Russian Federation — Atlantic regional direction that includes the Atlantic Ocean, rims of the Black Sea, Azov Sea, Baltic Sea and Mediterranean Sea. Attention is drawn to the notion of «Marine medicine», its role and place in national health care is argued. The necessity of practical implementation of the Convention of the International Labor Organization, ratified by the Russian Federation in 2012, No. 186 «On labor in maritime navigation», is primarily emphasized, first of all, the creation of national and regional centers of maritime medicine, bringing various issues of medical provision of subjects of marine activity in line with international standards. The author notes that the problem of adaptation the national medical education to the international system of education in the field of maritime health care in the coming years will require the introduction of additions to the list of medical specialties and qualification requirements in the part related to marine medicine. It is on the basis of the national and regional centers of maritime medicine in the Russian Federation that it is proposed to organize training (postgraduate training, retraining) of the medical staff. It is noted that the Russian Federation, based on wide and positive experience of medical provision of seafarers in the Soviet Union, taking into account the organizational, scientific, methodological and practical features of the activities of the international centers of maritime medicine, will consistently and steadily develop the medical supply system of the state’s maritime power.
Peningkatan Kemampuan Kognitif dan Afektif Siswa Pada Materi Substansi Genetik Menggunakan Model Picture and Picture dan Media Audiovisual Serta Papan Tempel di Kelas XII SMA Negeri 11 Muaro Jambi
Authors: Aina Mia 
Published: October 2018

Penelitian ini merupakan Penelitian Tindakan Kelas (PTK) yang bertujuan untuk meningkatkan kemampuan kognitif dan afektif siswa pada materi substansi genetik dengan menggunakan model pembelajaran picture and picture, media papan tempel dan media audiovisual. Penelitian Tindakan Kelas ini dilakukan sebanyak tiga siklus. Berdasarkan hasil Penelitian Tindakan Kelas (PTK) pada kelas XII SMA N 11 Muaro Jambi dengan menggunakan model pembelajaran picture and picture, media papan tempel dan video pada materi substansi genetik dapat meningkatkan kognitif dan afektif siswa dalam pembelajaran. Hal ini terlihat pada kelulusan klasikal kognitif siswa setiap siklusnya secara berturut-turut yaitu 17.3%, 39.1%, dan 43.4%. sedangkan untuk afektif yaitu 0%, 21.7%, dan 43.4%. Dari setiap perlakuan yang dihasilkan pada setiap siklusnya, dapat dikatakan bahwa penerapan model picture and picture, media papan tempel dan video cocok digunakan untuk mengajarkan materi substansi genetik di kelas XII IPA SMA N 11 Muaro Jambi, hal ini dapat terlihat dari terjadinya peningkatan baik ranah kognitif ataupun ranah afektif dari setiap siklusnya, sehingga dapat dikatakan bahwa penerapan model picture and picture, media papan tempel dan video dapat meningkatkan kognitif dan afektif siswa pada materi substansi genetik di kelas XII SMA N 11 Muaro Jambi.
Aspect Analysis in Higher Order Thinking Skills on the Evaluation Instrument of Protist Topic for the Grade 10 Senior Highschool Students
Authors: Putri Riri Rahmadani , Ahda Yuni , D Rahmawati 
Published: October 2018

Higher order thinking skills are essential for student future. The 2013 Curriculum demands the existence of an evaluation instrument to train student higher order thinking, not only the thinking skill in the lower cognitive domain, but also in a higher domain. One of the efforts to enhance higher order thinking skills is to engage students with the questions integrated by cognitive C4-C6. This study analysed aspects of higher order thinking in an evaluation instrument. This study used descriptive method by collecting evaluation instrument data used by teachers to evaluate a learning process. Evaluation instruments used by teachers at schools are still in the C1-C3 cognitive level (C1 47%, C2 47%, and C3 6%), the evaluation instruments are not eligible according to the standard applied. The skills demanded by the Fundamental Competency of the 2013 Curriculum. Higher order thinking skills of students are still relatively low, with the percentage mean of 52.03%. The low cognitive level obtained in the evaluation instrument used by the teachers is the reason of the low thinking level of the students.
Development of Teaching Problem Learning Model and Ability to Sharing Ability to Biological Competence Class VII Students of MTsN Pakan Rabaa
Authors: Sari Yulia Ratna , Ahda Yuni , Sumarmin Ramadhan 
Published: October 2018

The lack of student understanding on the topic of Biology presented by teacher may lead them towards a low achievement. This case could be seen from the low students’ average learning outcomes in the 7th grade Biology at MTsN Pakan Rabaa according to Minimum Completeness Criteria ( MCC ). One of the reasons is the traditional method of question and answer applied by the teachers. Biology teachers only emphasizes learning on cognitive aspects. The low level of student learning outcomes are also determined by the students’ prerequisite knowledge. In order to solve this problem, the use of Problem Based Learning and initial ability learning model was applied. The purpose of this study is to evaluate the effect of Problem Based Learning and Initial Ability learning models based on the competence of the student learning styles of 7th Grade Biology at MTsN Pakan Rabaa in 2014/2015 academic year. This research applied quasi experiment which used the static group comparison design. The population was all of the 7th grade MTsN Pakan Rabaa students in academic year of 2014/2015. Sampling technique used was saturated sampling technique and the participants for the experimental class were class VII A, with VII B as the control class. The research findings showed that (1) the students’ cognitive domain was significantly affected after the implementation of problem based learning model, except for those with high cognitive domain levels. (2) The students’ cognitive domain were improved significantly for both students with high and low ability. (3) The students’ psychomotor domain ability were improved significantly for both students with high and low ability (4) there was no interaction between the model of problem-based learning with the initial ability of students to learn biology cognitive competence of students.
POWER POINT: ISTRUCTIONAL DESIGN AND THE ROLE IN TEACHING AND LEARNING
Authors: Wijayanto Rhendy 
Published: October 2018

ABSTRACT
Instructional design is undoubtfully an important part of a teaching learning process. An integration between the teacher and the tools maximize the learning impact of the process. Several characteristics of a good instructional design are considered essential in achieving desired goals. In order to construct such instrument certain steps such as Analyze, Design, Develop, Implement, and Evaluate should be followed. Internal process of learning should also be considered so that the information effectively reached the desired outcome. In First Aid block , a PowerPoint Presentation was chosen because of its versatility to accommodate various type of modality in instructional design.

Keyword: Instructional design, powepoint, lecture, , teaching learning

ABSTRAK
Media pembelajaran tidak dapat dipungkiri memainkan peranan penting dalam proses belajar. Integrasi antara dosen dan materi akan memaksimalkan efek pembelajaran. Beberapa karakteristik dari media pembelajaran yang baik dianggap sangat penting untuk mencapai tujuan yang diinginkan. Dalam rangka mengembangkan media tersebut, langkah-langkah Analisis, Desain, Develop, Implementasi dan Evaluasi haruslah diikuti. Proses pembelajaran internal juga harus dipertimbangkan agar informasi dapat secara efektif mencapai hasil yang diinginkan. Dalam Blok Pertolongan Pertama, presentasi dengan PowerPoint dipilih karena kefleksibelannya dalam mengakomodasi berbagai modalitas media pembelajaran.

Kata Kunci: Media pembelajaran, powerpoint, kuliah, proses belajar
Diagnóstico de helmintiasis por videocápsula endoscópica
Authors: Arango Molano Lázaro Antonio , Jaramillo Mario , Ferreira Julián , Carvajal Jhon , Cardozo Marcos 
Published: October 2018

La helmintiasis corresponde a una parasitosis intestinal altamente prevalente en países en desarrollo, y que viene aumentando en los países desarrollados. Teniendo en cuenta el ciclo de vida de los helmintos, su presentación se relaciona con situaciones ambientales y socioeconómicas de alto riesgo. Por tanto, su presencia endémica puede considerarse un problema de salud pública. Para el diagnóstico, se disponen de varios elementos incluyendo estudio de materia fecal, endoscopia e imágenes diagnósticas como estudios de Rayos X de vías digestivas, TAC y Resonancia nuclear. En la actualidad existen reportes de diagnóstico de helmintiasis por cápsula endoscópica, que también han permitido el estudio de la ecología y patología in situ de éstos parásitos. Se presenta un caso clínico de helmintiasis compatible con estrongiloidosis, diagnosticado por cápsula endoscópica por el grupo de gastroenterología clínico quirúrgica de la universidad de Caldas, Colombia.
As mulheres do Harvard College Observatory: Henrietta Swan Leavitt - a mulher que descobriu como medir a distância das galáxias
Authors: De Barros Magali Conceição 
Published: October 2018

ResumoNo final do século XIX e início do século XX, algumas mudanças ocorreram na área da astronomia, entre elas, o desenvolvimento técnico/tecnológico, o aparecimento de novos observatórios e juntamente com eles o aperfeiçoamento dos telescópios e a introdução da fotografia na astronomia, que possibilitou o registro das observações que antes eram feitas através de desenhos. Outra mudança que ocorreu foi a entrada de mulheres na astronomia, o registro fotográfico de observações astronômicas permitiu, que em um ambiente masculino, mulheres pudessem adentrar e fazer suas pesquisas, pois embora não lhes fosse permitido fazer observações noturnas elas poderiam utilizar as chapas fotográficas. Para exemplificar a importância do trabalho feminino nesta época, vamos mostrar a pesquisa e de Henrietta Swan Leavitt que descobriu a Relação Período-Luminosidade de Estrelas Variáveis.Palavras-chave: História da Ciência; Mulheres na Astronomia; Régua Cósmica; Henrietta Swan Leavitt; Relação Período-luminosidade.AbstractIn the late 19th and early 20th, some changes occurred in the area of astronomy, among them technical / technological development, the appearance of new observatories and together with them the improvement of telescopes and the introduction of photography in astronomy that made possible the registration from earlier observations made through drawings. Another change that occurred was the entry of women into astronomy, the photographic record of astronomical observations allowed that in a masculine environment women could enter and do their research, because although they were not allowed to make nocturnal observations they could use photographic plates. To exemplify the importance of female work at this time, let's show the research and from Henrietta Swan Leavitt who discovered the Period-Luminosity Relationship of Variable Stars.Keywords: History of Science; Women in Astronomy; Cosmic Ruler; Henrietta Swan Leavitt; Period-luminosity relationship.
INSTABILITAS RENDEMEN CPO PADA INDUSTRI MINYAK SAWIT [CPO Yield Instability on Palm Oil Industry]
Authors: Subagya Fradana , Suwondo Endy 
Published: October 2018

The problem faced by the palm oil industry today is the instability of the Crude Palm Oil (CPO) yield. The condition of Fresh Fruit Bunches (FFB) starting from the time of harvesting to transporting to the factory, including during stockpiling at the palm oil mill, is an influential factor affecting the yield of CPO. This study aimed to find the factors causing instability of CPO yield in the palm oil industry. I-MR control maps and fishbone diagrams were used to analyze the factors that cause low CPO yields. From the data analysis for three years, the evidence of CPO yield was not statistically controlled. The causative factor of CPO yield instability included the quality of raw materials, production equipment, character of workers, and environmental conditions, with the dominating factor was the low quality of raw materials.
Circuitos Integrados Fotónicos para la Generación de Frecuencias Ópticas (OFCG)
Authors: Corral Carrera Vinicio Fabián , Carpintero Guillermo , Guzmán Robinson 
Published: October 2018

Se presentan los avances realizados en el desarrollo de generadores de peines de frecuencias ópticas (OFCG, Optical Frequency Comb Generator) mediante circuitos integrados fotónicos (PIC, Photonic Integrated Circuits). Estos son diseñados y fabricados en un proceso de oblea multi-proyecto de una plataforma genérica de integración. Se muestran los resultados experimentales de las diferentes clases de OFCG destacando los anchos de banda logrados, en el orden de THz. Se resalta la factibilidad de disponer circuitos fotónicos miniaturizados en sistemas de banda ancha y otras aplicaciones futuras en el marco de la nanotecnología.
Pervivencia clásica y configuración de un modelo. Apostillas a un Crucificado montañesino
Authors: Ramírez González Sergio 
Published: October 2018

Mediante su estudio histórico, estilístico e iconográfico, el presente trabajo pretende dar a conocer una interesante escultura de Cristo Crucificado que fue dada por desaparecida, a raíz de los sucesos de la Guerra Civil española, cuya hechura sigue muy estrechamente los modelos de Juan Martínez Montañés, posteriormente secundados por otros artistas del círculo hispalense del Seiscientos.
Futurism en la Tate
Authors: Martínez Silvente María Jesús 
Published: October 2018

Si jugáramos a elegir el motivo cultural que se ha repetido con más frecuencia durante este año nos quedaríamos, sin duda, con los homenajes al centenario del nacimiento del futurismo que han tenido lugar en diferentes ciudades europeas como Milán, Roma, Florencia o París. El más reciente ha sido la excelente FUTURISM de la Tate Modern en Londres.
Ana Rita Sá Carneiro y Ramona Pérez Bertruy: Jardines históricos brasileños y mexicanos
Authors: Morales Folguera José Miguel 
Published: October 2018

El origen de este libro, editado conjuntamente por dos editoriales universitarias de Brasil y México, se halla en un encuentro celebrado en Sevilla en el mes de julio del año 2006 con el nombre de Jardines Históricos Iberoamericanos.
González Torres, Javier: Emblemata Eucharistica. Símbolos animados de la iconografía cristológica y sacramental
Authors: Sánchez López Juan Antonio 
Published: October 2018

Desde los inicios de la Historia, la vida del ser humano ha permanecido estrechamente ligada a los animales. Más allá de las actividades económicas o de mera subsistencia, las relaciones del hombre con el animal se adentran hasta lo más profundo de su conciencia, imaginario y capacidades cognoscitivas.
AZNAR, Yato Y MARTÍNEZ, Pablo (eds.), Arte actual. Lecturas para un espectador inquieto.
Authors: Miranda Carlos 
Published: October 2018

La transformación de la función social del museo actual es un debate que responde a evidentes necesidades de canalización de las modificaciones que le exige hoy el propio contexto sociocultural en el que se inscribe, lo cual implica de modo particular a esa institución cuya identidad proviene precisamente de esta condición: el centro de arte contemporáneo. El CA2M, bajo la batuta de Ferran Barenblit desde su fundación en 2008, viene prestando especial atención a esta dimensión mediadora que se le presupone, para lo cual despliega todo un rico aparato de actividades de las cuales la publicación que aquí me ocupa no es sino un fruto más, si bien especialmente apetitoso, permítaseme la expresión.
Karakteristik Agronomis Tiga Varietas Padi (Oryza sativa L.) pada Dua Sistem Tanam Benih di Lahan Pasang Surut
Authors: Kriswantoro Haris , Safriyani Etty , , Purwaningsih , Herlinda Dan Siti 
Published: October 2018

<p>ABSTRACT<br /><br />The efforts to develop and increase rice production in tidal land need appropriate technologies including adaptable superior varieties and efficient seed planting system. This study was aimed to measure the agronomic characteristic of the three rice varieties on the systems of in-row direct seeding and broadcast in tidal land. The experiment was carried out at type B of tidal land in Sidoharjo Village, Air Saleh Subdistrict, Banyuasin District, from January to April 2016. The experiment was conducted using split plot design with four replications. The main plot was seed planting system, consisted of in-row direct seeding system and broadcast system; whereas subplot was three rice varieties, consisted of Inpari 22, Inpara 4, and Ciherang. Result of LSD test on interaction showed that though the best growth was obtained from the combination of Inpari 22 and in-row direct seeding and very significant with the others, but its yield was not significant with the combination of Inpara 4 and in-row direct seeding. It was concluded that Inpari 22 and Inpara 4 with in-row direct seeding system showed better growth and higher yield than Inpari 22, Inpara 4 and Ciherang with broadcast system in tidal lands. Ciherang was not suitable in tidal land, while Inpari 22 was suitable.<br /><br />Keywords: broadcast system, in-row direct seeding system, production</p>