bluuebunny/crossref_metadata_2025_split huggingface dataset:
Taste Threshold, Salivary Secretion, Blood Pressure and Blood Glucose in Smoking and Non-Smoking Women
Authors: Tjahajawati Sri , Rafisa Anggun , Pramesti Hening Tjaturina , Zubaedah Cucu 
Published: September 2019

Background: WHO reported that 2.7% of women are active smokers in Indonesia. Smoking can decrease taste sensitivity. The objective of this study was to obtain the taste threshold, salivary secretion, blood pressure and blood glucose in smoking and non-smoking women.
Materials and Methods: Subjects were 15 smoking women and 38 non-smoking women. The sweet and salt taste threshold was measured by dripping a solution of NaCl and glucose gradually starting from the lowest to the highest concentration. Blood glucose levels were measured using a glucometer device. Blood pressure was obtained by using a sphygmomanometer. Salivary volume is measured by spitting method. Salivary pH value was measured using pH paper test.
Results: The mean value of sweet taste threshold (0.04267 M), salt taste threshold (0.03267 M), salivary volume (2.78667 ml), blood glucose (112.83333 mg/dl) and systolic blood pressure (111.53333 mmHg) in smoking women were higher than the mean value of sweet taste threshold (0.03132 M), salt taste threshold (0.02513 M), salivary volume (2.73026 ml/5 min), blood glucose (107.36842 mg/dl) and systolic blood pressure (109.89474 mmHg) in non-smoking women. In contrast, the mean value of salivary pH (6.00) and diastolic blood pressure (73.46667mmHg) in smoking women were lower than the mean value of salivary pH (6.25) and diastolic blood pressure (76.18421 mmHg) in non-smoking women. There was a significant difference of sweet and salt taste threshold between smoking and non-smoking women (p<0.05).
Conclusion: Systolic blood pressure was the most contributing variable on explaining the difference in smoking and non-smoking women, followed by the sweet and salt taste threshold.
Sjögren's syndrome-literature review and clinical case presentation
Authors: Mihaylova Zornitsa , Stanimirov Pavel 
Published: September 2019

Sjögren's syndrome (SS) is a systemic disorder with clinical presentation of dry eyes, dry mouth and autoimmune disorder. Recently the number of patients with SS is increasing. In middle age female patients, having symptoms of dry mouth and salivary glands enlargement, SS should always be suspected. We present a clinical case report of a patient with SS. Based on the therapy and long term follow-up, we may conclude that via appropriate treatment significant improvement could be achieved.
The Negative Behaviors in Healthcare Survey: Instrument Development and Validation
Authors: Layne Diana M. , Nemeth Lynne S. , Mueller Martina , Wallston Kenneth A. 
Published: September 2019

Background and PurposeExamine the psychometric properties and factor structure of the Negative Behaviors in Healthcare (NBHC) Survey.MethodsA principal axis factor analysis with varimax rotation was conducted utilizing the 2012 NBHC survey data (n = 1,918) to explore the underlying structure of the NBHC instrument. A confirmatory factor analysis using AMOS 23 (Arbuckle, 2014) was then conducted using the 2014 NBHC survey data (n = 1,479).ResultsInternal consistency reliability was supported for four of the five identified factors, while construct validity for a five factor solution was established with acceptable model fit indices (Goodness of Fit Index [GFI] = 0.98; Relative Fit Index [RFI] = 0.98, Normed Fit Index [NFI] = 0.98, Root Mean Square Residual [RMR] = 0.05).ConclusionsThe NBHC instrument is a valid reliable instrument to assess negative behaviors among interprofessional healthcare team members, adding to a select few available instruments measuring negative behavior among interprofessional healthcare workers.
Evidence of Arabic Version of the Control Attitude Scale-Revised Efficacy to Measure Perceived Control in Acute Myocardial Infarction Patients
Authors: AbuRuz Mohannad Eid 
Published: September 2019

Background and PurposePerceived control plays a vital role in controlling negative consequences during disease process. The purpose of this study was to test the psychometric properties of the Arabic version of the Control Attitudes Scale-Revised (CAS-R) among patients with acute myocardial infarction (AMI).Methods375 patients with a confirmed diagnosis of AMI participated in this study. Reliability was assessed by Cronbach's alpha, item-total correlations, and interitem correlations. Construct validity was examined by hypotheses testing.ResultsCronbach's alpha was .85. All items were homogenous, since item-total correlation coefficients and interitem correlation coefficients were acceptable. Perceived control has a protective effect against anxiety and complications, supporting the construct validity.ConclusionsThe Arabic version of the CAS-R is a valid and reliable instrument to measure perceived control in patients with AMI.
Validation of the Assault (Violence) Response Scale: An Update
Authors: Lanza Marilyn , Schultz Mark 
Published: September 2019

Background and PurposeThe Assault (Violence) Response Questionnaire has been used widely in the United States, Europe, Asia, and Africa since the 1980s. The purpose is to update the ARQ.MethodSpecifically the ARQ-R has been expanded to include verbal assault and withholding information, more extensively tested for reliability and validity, and shortened.ResultsThe scale was reduced from 88 to 33 items and yet had the same high reliability and validity as did the larger scale.ConclusionsThe reduction in size makes it much less time consuming to complete, making it an instrument that very busy nurses can more easily use. The ARQ-R can be used for nurses measuring assault in both hospital and community settings.
Acidose Tubular Renal Distal: Expressão Clínica Variável na Mesma Família
Authors: Ramos Daniela , Reis Sofia , Cordinhã Carolina , Carmo Carmen do , Gomes Clara , Correia António Jorge 
Published: September 2019

A acidose tubular renal distal primária deve-se a um defeito genético caracterizado pela incapacidade de acidificar a urina. A sintomatologia é inespecífica e muito variável. Descrevem-se seis casos de acidose tubular renal distal numa família em que a doença afetou quatro gerações. O primeiro caso foi diagnosticado aos três anos por hematúria e urolitíase. Posteriormente foram estudados a irmã, os dois filhos e dois sobrinhos do caso índex. Apesar de assintomáticos, todos apresentavam nefrocalcinose e acidose metabólica hiperclorémica, à exceção de um caso com gasimetria normal mas com nefrocalcinose e incapacidade de acidificação urinária. Na evolução todos mantiveram nefrocalcinose, o caso índex desenvolveu hipertensão arterial mas nenhum evoluiu para insuficiência renal crónica. O diagnóstico da acidose tubular renal distal autossómica dominante é geralmente mais tardio e com sintomatologia mais ligeira. A doença pode contudo manifestar-se precocemente e com espectro de gravidade variável. O rastreio pela história familiar permite antecipar o diagnóstico e iniciar tratamento mais precocemente.
Doença Metabólica Óssea da Prematuridade em Recém-Nascidos de Muito Baixo Peso: Estudo Observacional Retrospetivo
Authors: Costa Raquel , Franco Catarina , Santos Nádia , Maio Patrícia , Vieira Filipa , Antunes Sónia , Martins Laura , Tuna Madalena Lopo 
Published: September 2019

Introdução: A doença metabólica óssea da prematuridade consiste numa diminuição da matriz óssea, relativamente ao nível esperado para a idade gestacional. O rastreio baseia-se no doseamento sérico da fosfatase alcalina e fósforo. O objetivo deste estudo é avaliar a prevalência da doença metabólica óssea da prematuridade, analisar os aspetos associados a maior risco para esta doença e descrever o crescimento estaturo-ponderal dos recém-nascidos com peso ao nascer inferior a 1500 g, com doença metabólica óssea da prematuridade.Material e Métodos: Estudo multicêntrico, retrospetivo, observacional e descritivo em três unidades de apoio perinatal diferenciado, entre 1 de maio de 2016 e 30 de abril de 2017; foi obtida uma amostra de conveniência de recém-nascidos com muito baixo peso ao nascer. Descrevem-se as variáveis demográficas, clínicas e laboratoriais dos recém-nascidos com e sem doença metabólica óssea da prematuridade.Resultados: Neste estudo foram incluídos 53 recém-nascidos: 30 do sexo masculino, 16 com idade gestacional ≤ 28 semanas. Foram diagnosticados cinco casos de doença metabólica óssea da prematuridade. Neste grupo, a maioria dos doentes era do sexo masculino e apresentavam idade gestacional e peso ao nascer inferior aos do grupo sem doença metabólica óssea da prematuridade. A duração média de nutrição parentérica foi superior nos recém-nascidos com doença metabólica óssea da prematuridade e a relação cálcio/fósforo utilizada foi inferior às recomendações nacionais. A evolução estaturo-ponderal foi semelhante nos recém-nascidos com e sem doença. Nenhum doente com doença metabólica óssea da prematuridade teve intervenção por medicina física e reabilitação.Discussão: A prevalência de doença metabólica óssea da prematuridade foi de 9,43%, valor inferior ao descrito na literatura. Contudo, apenas 50% dos recém-nascidos cumpriram o rastreio de acordo com as recomendações. Os principais fatores de risco identificados estão de acordo com a literatura.Conclusão: A doença metabólica óssea da prematuridade é uma comorbilidade frequente nos recém-nascidos de muito baixo peso, mas encontra-se subdiagnosticada. É fundamental rastrear os recém-nascidos em risco para esta patologia, utilizando marcadores bioquímicos, assim como estruturar intervenções nutricionais e estimulação física para evitar as consequências da doença a curto e longo prazo.
Recommendations from a Portuguese Expert Group for Discontinuation of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients in Clinical Practice
Authors: Almeida Antonio , Pierdomenico Francesca , Guerrero Blanca Polo , Saraiva Filipa , Montalvão Ana , Coutinho Jorge , Mariz Mário , Melo Teresa , Santos Maria João , Pereira Alexandra , Cerveira Nuno 
Published: September 2019

Until recently, the main goal of chronic myeloid leukemia therapy was disease control with the best overall survival, which required lifelong treatment. However, currently, the treatment-free remission concept is becoming an important goal in clinical practice, and several tyrosine kinase inhibitors discontinuation studies have shown that round 50% of patients with a durable deep molecular response beyond major molecular response successfully interrupt tyrosine kinase inhibitors for at least three years without loss of molecular response. However, and regardless of the existing evidence, the exact conditions for attempting treatment-free remission remain poorly defined. Different authors tried to guide the clinical decision regarding this topic but there are some points that differ, namely with respect to the recommended duration of tyrosine kinase inhibitors therapy and the appropriate molecular response prior to treatment-free remission. The goal of this article is to propose an algorithm to guide clinical practice in Portugal concerning chronic phase-chronic myeloid leukemia patients who wish to attempt treatment-free remission, since there are no national guidelines.
Vacinas Vivas em Crianças com Síndrome de DiGeorge/Deleção 22q11.2
Authors: Miranda Mariana , Martins Andreia Teixeira , Carvalho Sara , Serra-Caetano Ana , Esteves Isabel , Gonçalo Marques José 
Published: September 2019

Introdução: A síndrome de DiGeorge/deleção 22q11.2 pode apresentar um grau variável de imunodeficiência, condicionando a utilização de vacinas vivas. Este estudo teve como objetivo documentar os efeitos adversos de vacinas vivas e possível relação com alterações imunitárias em crianças com síndrome de DiGeorge/deleção 22q11.2 parcial.Material e Métodos: Foi realizado um estudo retrospetivo por revisão dos processos clínicos das crianças com deleção do cromossoma 22q11.2 e fenótipo de síndrome de DiGeorge, seguidos num centro de referência de imunodeficiências primárias. Foi realizada colheita de dados, incluindo: características demográficas; história médica; historial de vacinação com vacinas vivas; contagem de linfócitos T-CD4+ e respostas proliferativas linfocitárias a antigénios e mitogénios; reações adversas; falências vacinais.Resultados: Foram incluídas 23 crianças com síndrome de DiGeorge/deleção 22q11.2, 65,2% do sexo masculino e idade média de diagnóstico de 11,3 meses. Destas, 18 crianças (78%) receberam a vacina bacillus Calmette-Guérin: todas com evidência de atividade tímica; três apresentaram linfopénia T-CD4+ moderada e respostas proliferativas linfocitárias anormais; uma com respostas proliferativas linfocitárias anormais para mitogénios, quatro para derivado de proteína purificada e uma para toxóide tetânico. A vacina tríplice contra o sarampo, parotidite e rubéola foi administrada a 15 crianças, três com imunossupressão moderada e respostas proliferativas linfocitárias anormais. A vacina viva atenuada contra poliomielite foi administrada a quatro crianças sem imunossupressão e a vacina contra o rotavírus a três crianças, uma com imunossupressão moderada. Não foram reportadas reações adversas.Discussão: Estes dados estão de acordo com as conclusões de outros estudos internacionais.Conclusão: Na nossa amostra, as vacinas vivas atenuadas foram bem toleradas, incluindo em crianças com linfopénia T-CD4+ moderada e com respostas proliferativas linfocitárias a antigénios/mitogénios anormais.
In vitro protocol optimization for development of interspecific hybrids of oil palm (Elaeis oleifera (H.B.K) Cortés x Elaeis guineensis Jacq.)
Authors: Alves Sergio Agusto Oliveira , Lemos Oriel Filgueira de , Filho Benedito Gomes dos Santos , Silva André Luís Lopes da 
Published: September 2019

O dendezeiro (Elaeis guineensis) é a maior fonte de óleo vegetal no mundo. Porém, a doença do amarelecimento fatal está dizimando plantações no estado do Pará, Brasil. Para superar esse problema, híbridos interespecíficos de Elaeis oleifera x Elaeis guineensis são uma alternativa viável. Contudo alguns protocolos para o resgate in vitro desses embriões já foram estabelecidos, porém é necessário otimizá-los. O objetivo dessa pesquisa foi otimizar o protocolo in vitro para o cultivo de embriões interespecíficos de (Elaeis oleifera x Elaeis guineensis). A desinfestação das sementes foi realizada com 1 ou 2% de NaOCl por 20 ou 40 minutos. Embriões foram germinados in vitro na presença de 0; 0,1; 0,2 e 0,25% de carvão ativado e embriões foram cultivados na presença do ácido 2,4-diclorofenoxiacético (2,4–D) nas concentrações de 375, 500 e 625 μM para a indução de calos. A adição de 2,5% de carvão ativado é necessária para reduzir a oxidação fenólica dos embriões. A desinfestação das sementes pode ser realizada com 1% de NaOCl por 20 minutos. Diferentes variedades possuem diferentes concentrações ideais de 2,4–D para a indução de calos. As melhores concentrações de 2,4–D foram 375 e 625 μM para as variedades SJ-167 e SJ-165, respectivamente.
Inventário de biomassa em um plantio de Pinus elliottii engelm. aos 23 anos de idade
Authors: Giongo Marcos , Silva Damiana Beatriz da , Koehler Henrique Soares , Marchetti Marco 
Published: September 2019

O presente trabalho estimou a biomassa aérea de um povoamento de Pinus elliotti, com 23 anos de idade, localizado no município de Rio Branco do Sul - PR. Foram avaliadas separadamente a biomassa do fuste, galhos e acículas. A biomassa seca total estimada é composta por 85% de fuste, 10% de galhos e 5% de acículas. O modelo ajustado para a estimativa de biomassa seca aérea total, em função do diâmetro a altura do peito (DAP), apresentou um coeficiente de determinação (R²) de 0,91 e erro padrão da estimativa (Sxy) de 11,98%. Dentre os modelos ajustados para estimar as diferentes porções de biomassa na árvore, o que estima a biomassa do fuste foi o que apresentou melhor relação entre biomassa e o diâmetro à altura do peito.
Palavras-chaves: Modelagem, biomassa, reflorestamentos
Upper Devonian (Frasnian) stromatactis-bearing mud mounds, western Alberta, Canada: reef framework dominated by peloidal microcrystalline calcite
Authors: Zhou Kai , Pratt Brian R. 
Published: September 2019

ABSTRACT
Two well-preserved mud mounds, approximately 50 m thick, in the Mount Hawk Formation (Upper Devonian, Frasnian) in western Alberta provide an unparalleled opportunity to study the microstructure of this reef type in detail for this time interval. This reveals that they are composed dominantly of peloidal sediments—more than a quarter of mud mound volume—along with dense micrite, particulate micrite, bioclasts, and stromatactis cavities. Five types of peloids are differentiated: bacterial, cyanobacterial, bioclastic, intraclastic, and pseudo-peloids. Bacterial peloids were generated by bacterial metabolic activities with possibly some contribution from organomineralization in areas within spicular networks. Three subtypes of cyanobacterial peloids are distinguished based on whether they are physically reworked calcified filaments, aggregates of calcified coccoids, or precipitated within stromatolite-forming cyanobacterial mats or biofilms. Bioclastic peloids are fully micritized fragments of skeletons and shells. Intraclastic peloids are eroded fragments of early-lithified matrix. Pseudo-peloids represent artifacts of poorly preserved sponge spicular networks reflecting the interplay between dissolution of spicules and organomineralization. The distribution of the various peloid types shows specificity in different microfacies. They prove to be valuable paleoecological indicators, and taken together suggest that the mud mounds accreted within the photic zone above storm wave base but below the fair-weather wave base, during deposition of a transgressive and perhaps highstand systems tracts. They are the products reflecting a dynamic balance between constructional versus destructive processes. Bacterial peloids combined with dense micrite constitute the framework, which in turn makes up close to 40% of the mud mounds. This indicates that microbial activities are responsible for the early-indurated framework. The onset of bacterial peloid formation in the bedded sediment immediately underlying the mud mounds further demonstrates that it may have been a necessary precursor to mud-mound initiation. Bacterial peloids appear to characterize most Paleozoic and Mesozoic reefal mud mounds as an essential framework element.
Dual use of alternative forms of cigarettes and traditional smoked tobacco in Pregnant Smokers
Authors: Bertani Andre , Tanni Suzana Erico , Godoy Irma 
Published: September 2019

Abstract
Background to assess the prevalence of concomitant use of alternative forms of tobacco and analyze tobacco smoking characteristics in pregnant women. Methods: 127 pregnant women who smoked conventional cigarettes were evaluated during prenatal care. Those signing the informed consent form responded to a specific questionnaire containing questions related to general characteristics, comorbidities, gestational history, smoking history, secondhand smoke, degree of nicotine dependence, motivation stage and the prevalence of concomitant use of alternative forms of tobacco. They were separated into those who smoked conventional cigarettes only and those who smoked conventional cigarettes associated with straw cigarettes, waterpipe and/or e-cigarettes. Results: Mean age was 26.9 ± 6.6 years, most had only elementary education and belonged to economic classes C and D. Diagnosis of pulmonary disease was reported by 23.6% and cardiovascular diseases by 53.5%. Twenty-five (19.6%) smoked conventional cigarettes only and 102 also smoked alternative forms of tobacco. Those who smoked only conventional cigarettes had significantly lower smoke-load than those using alternative forms of tobacco. Those who smoked conventional cigarettes and waterpipe had higher nicotine dependence than other groups. Secondhand smoking was common (82.6%) and 59.1% were contemplative in relation to cessation. Conclusions: The prevalence of alternative tobacco forms is high and factors such as smoking during previous pregnancy, alcohol consumption during current pregnancy and high smoke-load may have contributed to the maintenance of smoking in the gestational period.
Evaluation study of using ampicillin susceptibility to predict imipenem susceptibility of E. faecalis and E. faecium
Authors: guo lanfang , Yin Dandan , Guo Yan , Zheng Yonggui , Shi Qingyu , Yang Yang , Zhu Demei , Hu Fupin 
Published: September 2019

Abstract
Objective: To evaluate ampicillin to predict activity of Enterococcus faecalis and Enterococcus faecium to imipenem.
Methods: A total of 127 non-duplicated strains of Enterococcus faecalis and 124 strains of Enterococcus faecium were collected from 23 hospitals in China. The antimicrobial susceptibility testing was determinated using broth microdilution and disk diffusion.
Results: For all E. faecalis , when using penicillin/ampicillin results to predict susceptibility to imipenem (called as penicillin-imipenem prediction mode and amipicillin-imipenem mode), the categorical agreement (CA) and major error (ME) rate was 88.9%/95.3% and 6.3%/0%, whereas it was 89.7%/96.8% and 8.7%/1.6%, when using that results of disk diffusion, respectively. No very major error (VME) rate was founded for both prediction modes. For penicillin susceptible, ampicillin susceptible E. faecalis , the CA rate of ampicillin-imipenem prediction mode based on results from broth microdilution and disk diffusion to was both 100%, and neither was founded with VME or ME rate. For penicillin resistant, ampicillin susceptible E. faecalis , the CA rate of ampicillin-imipenem prediction mode based on results from broth microdilution and disk diffusion was 57.1% and 81.8%, respectively. And neither was founded with VME or ME rate. For penicillin resistant, ampicillin resistant E. faecalis , the CA/ME/VME rate of ampicillin-imipenem prediction mode based on results from broth microdilution and disk diffusion was 100%/0%/0% and 77.8%/22.2%/0%, respectively. For all E. faecium , the CA rate of penicillin-imipenem and ampicillin-imipenem prediction mode based on results from broth microdilution was 100% and 99.2%, and it was both 99.2% based on results from disk diffusion. ME and VME rate for all four prediction modes was 0%. For penicillin resistant, ampicillin resistant E. faecium , the CA rate was 100%, as well as penicillin susceptible, ampicillin susceptible E. faecium . None of prediction mode was found with ME or VME rate.
Conclusion: For penicillin susceptible, ampicillin susceptible or penicillin resistant, ampicillin resistant E. faecalis and E. faecium , ampicillin susceptibility results of broth microdilution could accurately predict in vitro activity of imipenem. However, for penicillin resistant, ampicillin susceptible E. faecalis and E. faecium , using ampicillin results to predict imipemem susceptibility of was poorly consistent.