bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on the Mechanism of Stress Sensitivity and Retrograde Condensation Coupling Effect on Reservoir Depletion Development in Fractured-Vuggy Carbonate Rocks
Authors: Liu Yang , Pan Yi , Xiong Yu , Sun Yang , Liang Bin , Sun Lei 
Published: November 2024

Summary
Deep and high-pressure carbonate gas condensate reservoirs develop a large number of cracks and holes, with strong interlayer heterogeneity and complex mechanisms. To clarify the fundamental reasons that affect the development efficiency of such condensate gas reservoirs, we take the typical fractured and vuggy carbonate rock reservoirs in China’s S condensate gas field as the object of study, and conduct experiments such as X-ray computed tomography (X-CT) scanning, high-temperature and high-pressure stress-sensitivity testing, and long-core depletion development experiments. From multiple parameters and perspectives, we describe the microscopic changes in the storage and seepage spaces of fractures and vuggy cores, as well as the changing patterns of the underground condensate oil and gas production. According to the research results, the increase in effective stress leads to the contraction and closure of the fractured and vuggy spaces in the core, resulting in a decrease in their size. Under deep, high-pressure conditions, carbonate reservoirs exhibit strong stress sensitivity, and the permeability of the core drops significantly with the increase in the formation’s effective stress. The coupling effect of stress sensitivity and retrograde condensation has different impacts on the development effect of different types of cores at different pressure stages. The vuggy cores experience greater changes in storage and seepage spaces, the overall permeability damage is strong, and the condensate oil recovery rate is ultimately lower than that of fractured cores. Therefore, it is of great significance to study the impact of stress sensitivity and retrograde condensation characteristics on the gas reservoir recovery rate. The research results can provide theoretical support for the efficient development of deep, fractured-vuggy carbonate condensate gas reservoirs.
Accounting for Negative Publicity in Project Economics
Authors: Holgate M. J. M. , Davies G. J. , Kerr S. A. , Johnston F. M. M. 
Published: November 2024

Management
Summary
The high-profile publicity generated by the Greenpeace campaign against deep-sea disposal of the Brent Spar demonstrated the power of public opinion to affect corporate image and operational decisions. Regulatory approval is not the only constraint on the granting a "license to operate," and corporations now ignore stakeholder values at their peril. Although quantifying soft issues, such as negative publicity and stakeholder concerns, is difficult, there is an increasing need to integrate conventional economics with public opinion when evaluating different possible development options. This paper seeks to set out a process for incorporating negative publicity directly into project economics.
We started with an outline study of the effects of two high-profile incidents of negative publicity: Hoover's "Free Flights to America" promotion and the ill-fated launch of Unilever's manganese accelerator soap powder. The results showed two distinct outcomes: the effect on corporate image and the direct effect on a project, such as the launch of a new product. The next step was to identify a number of possible outcomes to an escalating scenario of negative publicity within the oil and gas sector. The economic consequences of each possible outcome are expressed as risk-assessed values (RAV's) that are the product of the probability and the cost of each outcome. To show this, we took a hypothetical case of handling of sour gas in a new field development and looked at the possible outcomes from four options for handling the gas: flaring, gas reinjection, power generation and seawater absorption.
The method developed in this paper outlines a process for quantifying stakeholder values and potential negative publicity in the planning stages of potentially sensitive projects. The process provides a logical and transparent framework that encourages the exploration of these softer issues. It is designed to provide indicative, rather than definitive, values to show whether the inclusion of risk-assessed costs would alter the decision on the basis of conventional economics. The process also provides a guide for developing a consistent basis for decision making, checks the sensitivity of the development option to negative publicity, and highlights the cost critical areas.
Eye Yoga for Glaucoma: Recovery of Vascular Dysregulation and Visual Field Loss - A Randomized Controlled Trial
Authors: Zhou Wanshu , Fricke Luisa , Sabel Bernhard A. 
Published: November 2024

Abstract

Purpose
Because stress can aggravate primary open angle glaucoma (POAG) progress, we studied if stress reduction by eye muscle exercises and meditation (Eye Yoga, EY) and can normalize VD, intraocular pressure (IOP) and visual field (VF) function as a complementary, personalized approach of eye care.
Patients and Methods:
POAG patients were randomized 1:1 to an EY (n = 15) or control group (n = 12). While EY was practiced daily for one hours for one month at home using an iPod-audio guide, control patients read daily relaxing books. Outcome criteria were IOP, retinal vessel dynamics and VF recovery.
Results
After intervention, EY patients, but not controls, showed a 6.4% IOP reduction (p = 0.027). This was associated with VF improvement (mean deviation) which were greater in EY than controls (p < 0.001). Furthermore, in EY, but not controls, pattern deviation recovered in VF regions where microvessel (third order-branch) vasoconstriction improved (artery: p = 0.012; vein: p = 0.042) and EY mean artery diameter recovered significantly (p = 0.015). When pooling data of both groups, recovered VF regions, but not non-recovered fields, showed significantly larger arterial diameter gains (2.4 [-0.3-5.3] MU). Neither treatment had any adverse events.
Conclusions
Because EY is able to reduce vasoconstriction and improve VF function in POAG confirms the hypothesis that mental stress is a contributing, or even key mechanism of POAG, and improved blood flow a fundamental mechanism of vision recovery and restoration. Daily eye yoga home-exercises are a safe and effective complementary PPPM method which can be easily adopted for POAG care.
Trial Registration clinicaltrials.gov (NCT04037384)
Door-to-Door Overdose Harm Reduction: an Illinois Case Study
Authors: Mason Maryann , Johnson Bruce , Johnston Sean , Alexander Ursula , Ajala Oyindamola , Andrews Nia , Welch Sarah B. , Schaffner Chris 
Published: November 2024

Abstract

Background
Harm reduction for people who use drugs (PWUD) is an established evidence-based practice that encompasses a wide variety of services, delivery formats, and settings and has been named a priority in US drug policy. Harm reduction is focused on planning with communities and meeting PWUD where they are and encompasses a wide variety of interventions. We describe and report the feasibility, acceptability, and processes implementation outcomes for an innovative pilot drug overdose harm reduction intervention, Block-by-Block (BXB), focused on training for and distribution of naloxone and test strips in areas identified as high risk for fatal overdoses.
Case presentation
Begun in 2020, BXB operates in five pilot sites in four Illinois counties. Through partnerships with local organizations, BXB delivers harm reduction services in a private setting (home) or in a setting not specifically targeting PWUD (businesses, libraries, faith-based organizations, etc.) to reach PWUD and their friends, family and neighbors living in areas disproportionately affected by opioid overdose death. The intervention theory is based on acknowledgement that harm reduction services that require PWUD to visit a mobile unit, van or community organization, may not reach those in need or their friends, neighbors, and family for a variety of reasons including stigma associated with drug use, lack of awareness about these services, or where to locate them. Services delivered include education and training in the use of naloxone and fentanyl, xylazine and benzodiazepine test strips. Leave behind materials include naloxone, test strips and handouts with information on the intervention and local resources.
Conclusions
Results to date indicate that this intervention is feasible –over half (55%) of the doors approached were answered. Acceptability of the intervention as delivered is high --people at 75% of doors that were answered were interested in and received training and/or supplies. BXB is flexible in that it has been quickly adapted to changes in community conditions, the drug supply, and shifting high risk areas as they developed. This is a promising intervention that leverages available data and resources and is readily implementable in communities with support from a central program administrator and access to geo-coded data.
Investigation of the plasma reaction behavior of a Coke Oven Gas with trace oxygen in a coaxial DBD reactor
Authors: Nitsche Tim , Lohmann Heiko , Budt Marcus 
Published: November 2024

Abstract

The presented study shows experimental results with literature comparison for understanding of the oxygen removal in coke oven gas (COG) with plasma. The reaction of oxygen with the main COG components H2, CH4, and CO are investigated as well as the occurrence of potential side reactions as the splitting of CO2 and CH4. Further potential side reactions in the COG mixture known from literature as hydrogenation reactions are discussed in contrast to the observations of the experiments.
Addressing the role of COVID-19 pandemic-induced Mental Health Problems on the Emergence of suicide among Pregnant Women, Egypt: A case-control study”
Authors: Said Mervat , Fouad Eman , Hassan Walid , Al-Fath Amr Mostafa  Kamel Abu , Khalil Yomna Ahmed 
Published: November 2024

Abstract

Background
Before the emergence of the Coronavirus disease (COVID-19) pandemic, the research reported that pregnancy is associated with increased suicide risk. However, data regarding the impact of COVID-19 on suicidal risk is not conclusive, and most of the studies are derived from Western countries. This study aimed to identify the suicidal risk and clinical correlates among pregnant women in Egypt during the COVID-19 crisis. A case-control study design was used in this study and included 245 pregnant women, and an equal number of non-pregnant women served as the control group. Pregnant participants were recruited from the Outpatient Departments (OPD) attending antenatal care services within the Obstetrics and Gynecology clinic at Zagazig University Hospital (ZUH) in Sharkia, Egypt. The control group consisted of non-pregnant relatives accompanying the pregnant participants. Data were collected through interviews using a semi-structured questionnaire to gather sociodemographic and clinical information, along with the administration of the following scales: Depression, Anxiety, and Stress Scale-21 (DASS-21), Fear of COVID-19 Scale (FCV-19S), Impact of Event Scale-Revised (IES-R), and Beck Scale for Suicide Ideation (BSS).
Results
It indicated that the pregnant group had higher levels of anxiety, depression, and stress compared to the control group. Moderate to severe symptoms of Post-Traumatic Stress Symptoms (PTSS) were found in 18.1% of the pregnant women, compared to 12.2% in the non-pregnant group. Additionally, the pregnant group had a significantly higher mean total score on the BSS. Predictive factors for suicidal tendencies in the pregnant group included living in urban areas, a family history of suicide, changes in the employment status of the participants or their spouses, PTSS, and experiencing inter-partner violence (IPV) during the COVID-19 pandemic.
Conclusion
The COVID-19 pandemic has significantly impacted the mental well-being of pregnant women and increased the risk of suicide. Experiencing changes in employment status, particularly the husband, PTSS, and exposure to IPV are the most significant predictors of suicide during the COVID-19 crisis.
Design and Synthetic Utility of New HAT Organocatalysts Derived from Commercially Available Diamines
Authors: Maruoka Keiji , Jia JingWen , Kato Terumasa 
Published: November 2024

Abstract

A series of hydrogen-atom transfer (HAT) organocatalysts were conveniently prepared from commercially available diamine compounds, and their utility in photoinduced HAT catalysis ability was investigated. The combination of these readily available HAT organocatalysts with the Fukuzumi photoredox catalyst enables efficient and site-selective C−H alkylation of various functionalized substrates ranging from simple hydrocarbons to complex molecules. The site-selective C–H alkylation of multifunctional molecules has also been demonstrated. Notably, the sequential one-pot photoinduced dialkylations of bifunctional substrates can be realized. Mechanistic studies suggested that the 1-naphthylmethyl moiety on one nitrogen atom of the diamine compounds plays a crucial role in the reaction by inducing the facile generation of a cationic aminium radical on the other nitrogen of the diamine as an active intermediate for the HAT process.
The Impact of the African Continental Free Trade Area (AfCFTA) on the Ethiopian Economy
Authors: Mengistu Simachew , Fan Cui , Feleke Weldetensay 
Published: November 2024

Abstract

Using a GEPPML model, this study evaluates the possible effects of the AfCFTA on Ethiopia's economy. With fewer trade obstacles between member nations, the AfCFTA—the largest free trade area in the world by population—aims to improve intra-African and global commerce and spur economic growth. Ethiopia hopes to benefit from the AfCFTA by having more trade options, as the country is mostly dependent on agricultural exports. The study models the full implementation of the AfCFTA in both conditional and full endowment scenarios. The results showed that, under the full endowment scenario, the full implementation of AfCFTA raised Ethiopia's real GDP by 2.512% and total exports by 1.137%, greatly above average gains among member nations.
The Role of Enterprise Resource Planning In Cloud Computing services dissemination''A field study in the Yemeni governmental communication sector''
Authors: al-baham mohammed abdullah nasser , al-sanafi abdullah abdullah 
Published: November 2024

Abstract

The research aimed to discover The Role of Enterprise Resource Planning In Cloud Computing services dissemination in Yemeni governmental communication sector. The research used the descriptive analytical approach and the questionnaire as the main tool for data collection. The research population was all employees who use Enterprise Resource Planning in Yemeni governmental communication sector represented by (General Corporation for Telecommunications and Yemeni International Telecommunications Company- tell-Yemen) (the headquarters). The research concluded that there is an important role for Enterprise Resource Planning with its dimensions in disseminate Cloud Computing services in Yemeni governmental communication sector. The research recommended that, it is necessary for Yemeni governmental communication sector to make more studies to understand the relationship between customer relationship management, and Cloud Computing services dissemination, also make clear strategic plan for the transformation to the Cloud Computing, define the goals, the tasks, the activities, the responsibilities, the necessary steps to achieve it.
Optimising LED Light Spectra for Enhanced Shoot and Root Growth in Green and Red Pakchoi (Brassica rapa var. chinensis)
Authors: Kassim Rosniza , Singh Ajit , Yap Joshua 
Published: November 2024

Abstract

Light quality is a critical factor influencing plant growth, particularly in controlled environments where artificial lighting, such as LED lights, is used. This study investigates the effects of different LED light spectra on the shoot and root development of green and red pakchoi (Brassica rapa var. chinensis). Specifically, the study examines the impact of various combinations of red, blue, and green wavelengths on key growth parameters, including plant height, plant width, leaf number, leaf area, and root morphology. The results demonstrate that red-dominant light (100R) significantly enhances shoot elongation and leaf expansion, whereas the red-blue light combination (82R18B) promotes more vigorous and extensive root systems. Notably, the 82R18B light treatment was found to provide the most balanced growth between shoots and roots, producing plants with robust morphology and strong root structures essential for nutrient and water uptake. The study concludes with a recommendation for using the 82R18B light formulation in commercial pakchoi cultivation, as it optimizes both shoot and root development, leading to higher quality and more marketable crops. These results emphasise the significance of adjusting light spectra to optimise plant growth and productivity in controlled environment settings.
Enhanced Chromium removal from water using ball milled nano-biochar derived from Eichhornia crassipes (Water hyacinth)
Authors: M Mohanadevi , K Dhanabalan 
Published: November 2024

Abstract

Hexavalent chromium (Cr (VI)) contamination in water sources poses a significant threat to human health and the environment due to its toxicity and carcinogenicity. In recent years, biochar-based adsorbents have gained attention for their potential to effectively remove heavy metals from water. This study focuses on the synthesis and application of ball-milled nano-Eichhornia (water hyacinth) biochar (BMNEBC) as an innovative adsorbent for the removal of Cr (VI) from aqueous solutions. In this research, Eichhornia plant leaves were utilized as the precursor for biochar production through a pyrolysis process. The produced biochar was subjected to physical modification (ball milling) to obtain nano-sized particles, thereby increasing the surface area and porosity of the material. Batch adsorption experiments were conducted to evaluate the Cr (VI) removal efficiency of BMBNBC under various operating conditions, including initial Cr (VI) concentration, adsorbent dosage, contact time, and pH. The equilibrium adsorption data were fitted to different isotherm and kinetic models to analyze the adsorption mechanism and kinetics. The results indicated that BMBNBC exhibited a high affinity for Cr (VI) adsorption, with a maximum adsorption capacity of 293.2 mg/optimal operating conditions determined to achieve maximum removal efficiency, and the adsorption process was found to follow the Langmuir isotherm and pseudo-second-order kinetic model, suggesting monolayer adsorption and chemisorption as the predominant mechanisms.
Hydrogel containing decellularized spinal cord tissue induces M2 polarization in macrophages
Authors: Santos Marcelo Garrido dos , Franca Fernanda Stapenhorst , Pessi Augusto Vargas , Turck Patrick , Scholl Juliete , klein Adriane Bello , Figueiro Fabricio , Peres Alessandra , Pranke Patricia 
Published: November 2024

Abstract

Study design
Basic cellular study.
Objectives
The use of biomaterials for regeneration is a promising approach in the tissue engineering field, but some materials can cause an inflammatory response when introduced into an organism. Macrophages play a central role in controlling inflammation, and when exposed to a stimuli, they polarize into a pro-inflammatory (M1) or anti-inflammatory (M2) phenotype. In this study, an evaluation was madeof macrophage polarization and inflammatory response when exposed to a hydrogel, used to produce a bioink, containing Decellularized Spinal Cord Tissue (DSCT) using RAW 264.7 macrophages.
Setting
Stem Cells Research Institute, Brazil.
Methods
Macrophages were exposed to the hydrogel for 24 hours. Cell viability was analyzed by MTT and Live/Dead assay. Flow cytometry was used to evaluate macrophage polarization and mitochondrial membrane potential. Cytokines, ROS (reactive oxygen species) production, sulfhydryl compounds and TBARS were quantified to assess inflammatory response. PC12 cells were exposed to macrophage conditioned medium and MTT was used to analyze cell viability.
Results
Although macrophage exposure to the hydrogel altered its metabolic activity, no cytotoxic effect nor oxidative damage was shown. Hydrogel induced an increase in IL-10 levels. The presence of DSCT in the biomaterial induced a decrease in CD45 and CD69 expression as well as an increase in CD206, a classic M2 marker, in comparison to the controls and the hydrogel without DSCT.
Conclusion
The hydrogel induced M2 polarization in the macrophages and a decrease in the inflammatory response. This biomaterial may be a suitable alternative for spinal cord regeneration after SCI.
Overlap Syndrome Involving Multiple Sclerosis and Kikuchi–Fujimoto Disease Following COVID-19 Vaccination: A Case Report
Authors: Liu Ruihua , Zhao Pengyue , Zhang Yunting , Li Yan , Duan Zhihui , Li Shao , Shang Dandan , Du Yanjiao 
Published: November 2024

Abstract

Background: Multiple sclerosis (MS) is an immune-mediated disorder of the central nervous system, while Kikuchi–Fujimoto disease (KFD) is a rare type of lymphadenitis. The overlap of MS with KFD following COVID-19 vaccination has not been previously reported.
Case presentation: A 23-year-old Asian woman presented with lymphadenopathy and diplopia following COVID-19 vaccination. A biopsy of the cervical lymph node confirmed KFD, while magnetic resonance imaging (MRI) revealed demyelinating lesions consistent with MS. The presence of cerebrospinal fluid (CSF)-specific oligoclonal bands met the criteria for dissemination in time. The final diagnosis was MS overlapping with KFD. The patient was treated with intravenous methylprednisolone and intravenous immunoglobulin followed by dimethyl fumarate capsules to prevent recurrence. Three years later, she experienced dizziness and diplopia again. Follow-up MRI of the brain revealed multiple abnormal signals in both the cortical and subcortical regions, with some areas showing partial enhancement, suggesting a relapse of MS. After administering another steroid pulse therapy, the disease-modifying therapy was switched to ofatumumab. Follow-up assessment demonstrated significant improvement in the patient’s dizziness and diplopia.
Conclusion: This case is the first to describe the occurrence of MS overlapping with KFD following COVID-19 vaccination. This case demonstrates that shared pathogenic mechanisms and common genetic susceptibilities may contribute to the simultaneous development of both conditions. Close monitoring is essential to exclude the potential presence of lymphoproliferative disorders and autoimmune diseases.
Palladium-Catalyzed Enantioselective β-Hydride Elimination for the Construction of Remote Stereocenters
Authors: Zi Weiwei , Sun Shaozi , Sun Shengnan 
Published: November 2024

Abstract

The β-H elimination is a crucial elementary step in transition-metal catalysis, but controlling the stereochemistry of this process has been underdeveloped. The limited works reported so far have only focused on creating axial chirality in allenes, and no report has been able to build central chirality using asymmetric β-H elimination. In this study, we report a Trost ligand-enabled enantioselective desymmetric β-H elimination reaction from π-allyl-Pd. This transformation provides rapid access to cyclohexenes bearing a C4-remoted stereocenter, and total synthesis of (-)-oleuropeic acid and (-)-7-hydroxylterpineol was demonstrated. Computational studies have shown that the β-H elimination is the rate-determining step, and the non-covalent interactions between the amide moiety of the Trost ligand and the benzene and cyclohexane moieties of the substrate play a key role in stereocontrol during the β-H elimination.