bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pratique de l’éducation thérapeutique du patient en Côte d’Ivoire : enquête auprès des professionnels de santé
Authors: Konan Yao Eugène , Kivits Joëlle , Tanguy Maurice , Guillemin Francis , Bénie Bi Vroh Joseph 
Published: September 2019

Introduction	: L’éducation du patient, ou éducation thérapeutique du patient, est une composante importante dans la prise en charge et le suivi des maladies chroniques. Elle joue un rôle important dans la baisse de la charge de morbidité, de mortalité et du poids socio-économique de ces pathologies et de leurs complications. En Côte d’Ivoire, il existe peu d’études permettant d’évaluer la pratique d’activités éducatives du patient.	Objectif	: Cette étude visait à explorer la pratique de l’éducation thérapeutique des patients atteints de maladies chroniques en Côte d’Ivoire.	Méthode	: Une étude qualitative a été menée par entretiens semi-directifs auprès de 24 professionnels de santé, dont 14 gestionnaires des structures sanitaires pour les entretiens individuels et 10 prestataires de soins pour les entretiens de groupe.	Résultats	: Le flou caractérise la notion d’« éducation du patient » avec une diversité des représentations chez les professionnels de santé. On constate qu’il n’y a pas de distinction véritable entre l’ETP et le concept plus large d’« éducation pour la santé ». L’absence de politique nationale d’ETP, le manque de formation en ETP et l’inexpérience de la pratique éducative amènent les professionnels de santé à conduire une démarche éducative non structurée.	Conclusion	: Ces résultats soulignent la nécessité pour la Côte d’Ivoire de disposer d’une politique nationale d’ETP permettant l’éducation des malades conformément aux recommandations internationales.
On modelling the kinematics and evolutionary properties of pressure-pulse-driven impulsive solar jets
Authors: Singh Balveer , Sharma Kushagra , Srivastava Abhishek K. 
Published: September 2019

Abstract. In this paper, we describe the kinematical and evolutionary properties of the impulsive cool jets in the solar atmosphere using numerical simulation by Godunov-type PLUTO code at two different quiet-Sun magnetic field strengths (B=56 gauss and B=112 gauss). These types of chromospheric jets originate due to a pressure pulse, which mimics the after-effects of the localized heating in the lower solar atmosphere. These jets may be responsible for the transport of mass and energy in the localized upper atmosphere (i.e. corona). The detection of the height–time profiles for the jets, which were developed by imposing different pressure pulses, exhibit asymmetric near-parabolic behaviour. This infers that the upward motion of the jet occurs under the influence of pressure perturbation. However, its downward motion is not only governed by the gravitational free fall, but also by the complex plasma motions near its base under the effect of counter-propagating pulses. The maximum height and lifetime of the jets with respect to the strength of the pressure pulse show a linear increasing trend. This suggests that if the extent of the heating and, thus, the pressure perturbations are longer, then more longer chromospheric jets can be triggered from the same location in the chromosphere. For a certain amplitude of pressure pulse, the strong magnetic field configuration (B=112 gauss) leads to more longer jets compared with the weaker field (B=56 gauss). This suggests that the strong magnetic field guides the pressure-pulse-driven jets more efficiency towards the higher corona. In conclusion, our model mimics the properties and evolution of the variety of the cool impulsive jets in the chromosphere (e.g. macrospicules, network jets, isolated repeated cool jets, confined and small surges, and so on.).
Shared Inuit Culture: European Museums and Arctic Communities
Authors: Buijs Cunera 
Published: September 2019

Since the 1980s, museum professionals have increasingly committed to sharing collections with the descendants of people and communities from whom the collected artifacts originated. As late as the 1970s, Indigenous people were not considered stakeholders in the collection and exhibition of their own cultural artifacts. Recently, however, exemplary cases of collection sharing have occurred in North American and European museums. Museums have become “contact zones” as issues of decolonization have come to the fore. This article discusses the sharing of material culture and “double” position of anthropological museums, rooted in their own (colonial) history but in possession of another’s culture. Ownership issues, access, and ethics are important for local communities but not always easy for museums to negotiate. This article describes thirteen examples of collaborative partnerships between museums, for the most part large, urban, European, postcolonial institutions, and Arctic Indigenous communities. I argue that open communication, collection research, and an increasing level of co-curation are prerequisites for changes in museum practice, and these changes will benefit both the institutions and the communities involved.
Deux musées pour un héritage : Les collections unangax̂ de l’île d’Unga
Authors: Salabelle Marie-Amélie , Alix Claire , McLain Allison Y. 
Published: September 2019

Cet article s’intéresse aux destins parallèles de deux collections unangax̂ (aléoutes) constituées dans la seconde moitié du XIXesiècle par le Français Alphonse Pinart et l’Américain William Dall. Fondées sur une rivalité entre ces deux personnages, ces collections, issues de leurs explorations respectives de cavernes funéraires de l’île d’Unga, forment un ensemble d’objets aussi unique qu’énigmatique, divisé entre le Château-Musée de Boulogne-sur-Mer (France) et le National Museum of Natural History de la Smithsonian Institution (États-Unis). Les auteures retracent ici le parcours singulier de ces objets qui, malgré leur caractère exceptionnel, restent à ce jour encore très peu étudiés.
Effect of Starter Solution and Age of Seedling on Growth and Yield of Broccoli (Brassica Oleracea Var. Italica)
Authors: Soniya Ismita Akter , Mostarin Tahmina , Khatun Khaleda , Haq Md. Ehsanul , Akhter Sanjida , Sharmin Iffat , Monira Shirajum , Parvin Anannya 
Published: September 2019

A study was conducted at central farm of Sher-e-Bangla Agricultural university, Dhaka during the period of October, 2017 to March, 2018 to investigate the influence of starter solution and age of seedling on the growth and yield of broccoli. The experiment consisted of two factors. Factor A: Four levels of starter solution as S0= 0% urea solution (control), S1= 1% urea solution, S2= 2% urea solution, S3= 3% urea solution and Factor B: Three levels of age of seedling as A1= 20 days of seedling, A2= 30 days of seedling, A3= 40 days of seedling. Application of the treatment influenced independently and also in combination on the growth and yield of broccoli. In case of starter solution, the highest yield (24.32 t/ha) was obtained from S2 (2% urea) treatment, whereas the lowest yield (13.21 t/ha) was recorded from S0 (0% urea) treatment. For three level of age of seedling the highest yield (20.75 t/ha) was obtained from A2 (30 days old seedling) treatment and the lowest yield (15.48 t/ha) was recorded from A3 (40 days old seedling) treatment. In case of combined effect the highest yield (26.91 t/ha) of broccoli was obtained from the treatment combination of S2A2 while the lowest (13.41 t/ha) was obtained from S0A3 treatment combination. Economic analysis revealed that S2A2 treatment combination was the best in respect of net return (3,24,890 tk) with benefit cost ratio of 2.5. So it may be concluded that 2% starter solution and 30 days age seedling was best for growth and yield of broccoli.
Redox Economic Synthesis of TrisubstitutedPiperidones via Ruthenium Catalyzed Atom‐Economic Couplings of N‐Protected 1,5‐Aminoalcohols and Michael Acceptors
Authors: Trost Barry M. , Sarkar Debayan , Bera Nabakumar 
Published: September 2019

AbstractAn efficient atom‐economic coupling of 1,5‐amino alcohols and Michael acceptors has been developed employing [CpRu(MeCN)3]PF6 as a key catalyst to synthesize α,β‐unsaturated ketones with exclusive generation of E‐geometrical isomers at room temperature without any co‐catalyst and additives. A base catalysed 6‐endo‐trig cyclization of the α,β‐unsaturated ketone delivers a direct access to tri‐substituted piperidones.magnified image
Free mucosal grafts and anterior pedicled flaps to prevent ostium restenosis after endoscopic modified Lothrop (frontal drillout) procedure: a randomized, controlled study
Authors: Wang Ying‐Piao , Shen Ping‐Hung , Hsieh Li‐Chun , Wormald Peter‐John 
Published: September 2019

BackgroundThe endoscopic modified Lothrop procedure (EMLP) is used to manage ongoing refractory frontal sinusitis after failed previous endoscopic sinus surgery (ESS), but this approach has a significant restenosis rate. We evaluated the potential benefits of mucosal grafts and pedicled flaps on the opening of the newly formed frontal ostium.MethodsFifty patients with refractory frontal sinusitis or mucoceles after ESS were randomized to undergo EMLP, either with (n = 27) or without (n = 23) mucosal grafts and pedicled flap reconstruction of the neo‐ostium. The frontal neo‐ostium was measured with Lindholm distending forceps, and anteroposterior (A‐P) and lateral dimensions were measured intraoperatively, and then again at 6 weeks, 6 months, and 12 months postoperatively. Olfaction outcomes were assessed using the Taiwan Smell Identification Test (TWSIT) and a smell visual analog scale (VAS) score preoperatively and at 6 months postsurgery.ResultsThe initial intraoperative mean lateral and A‐P dimensions were 23.2 ± 2.7 mm and 14.8 ± 2.3 mm and were significantly decreased at all time‐points postoperatively. The mucosal grafts and pedicled flaps had greater lateral and A‐P dimensions, and a greater percentage of intraoperative frontal neo‐ostium area at all time‐points postoperatively (all p < 0.05). At 6 months postoperatively, TWSIT (p = 0.027), but not the smell VAS score (p = 0.063), was significantly improved compared with baseline. TWSIT and smell VAS score changes did not differ between groups (p = 0.92 and p = 0.85, respectively).ConclusionThe use of mucosal grafts and pedicled flaps reduces stenosis of the frontal neo‐ostium postsurgery and should be considered after EMLP.
Impact of adjuvant chemotherapy on the survival of patients with breast cancer diagnosed by screening
Authors: Zarcos‐Pedrinaci Irene , Redondo Maximino , Louro Javier , Rivas‐Ruiz Francisco , Téllez Teresa , Pérez Diego , Medina Cano Francisco , Machan Kenza , Domingo Laia , Mar Vernet Maria , Padilla‐Ruiz Maria , Castells Xavier , Rueda Antonio , Sala María ,   REDISSEC‐CaMISS Group
Published: September 2019

AbstractThe aim of this study is to determine the survival of patients with breast cancer treated with adjuvant chemotherapy (ACh) after the diagnosis by screening, taking comorbidity into account. This multicenter cohort study examined a population of patients taking part in four national screening programs for the early detection of breast cancer (localized or locally advanced), during the period 2000‐2008. Of the 1248 cancers detected, 266 were prevalent (21.3%), 633 were incident (50.7%), and 349 were interval (27.9%). No significant differences were detected between the three groups in terms of the distribution of comorbidity according to the CCI. After a median follow‐up of 102 months, 22.1% of the patients with interval cancer had died. The corresponding figures for the incident and prevalent cancers were 10.4% and 7.9%, respectively (P < .001). The adjusted Cox regression analysis by the stage, CCI and group revealed no differences in the risk of recurrence between the different groups according to the ACh performed. However, there were significant differences in the overall survival; for the interval cancer group without ACh, the risk of death was higher (Hazard ratio: 2.5 [1.0‐6.2]) than for the other two groups. However, for the prevalent and incident groups that did not receive ACh, there was no greater risk of death. This study shows that adjuvant chemotherapy seems to benefit patients with interval breast cancer, who have a poorer prognosis than those with prevalent or incident cancer. However, the role of ACh is unclear with respect to prevalent and incident cancers when comorbidity is taken into account.
A Quencher‐Free Linear Probe from Serinol Nucleic Acid with a Fluorescent Uracil Analogue
Authors: Murayama Keiji , Asanuma Hiroyuki 
Published: September 2019

AbstractWith the goal of developing a quencher‐free probe composed of an artificial nucleic acid, the fluorescent nucleobase analogue 5‐(perylenylethynyl)uracil (PeU), which was incorporated into totally artificial serinol nucleic acid (SNA) as a substitute for thymine, has been synthesized. In the context of a 12‐mer duplex with RNA, these fluorophores reduce duplex stability slightly compared with that of an SNA without PeU modification; thus suggesting that structural distortion is not induced by the modification. If two PeUs were incorporated at separate positions in an SNA, the fluorescent emission at λ≈490 nm was clearly enhanced upon hybridization with complementary RNA. A quencher‐free SNA linear probe containing three PeUs, each separated by six nucleobases, has been designed. Detection of target RNA with high sensitivity and discrimination of a single‐base mismatch has also been demonstrated.
Biological Effects of a Simplified Synthetic Analogue of Ion‐Channel‐Forming Polytheonamide B on Plasma Membrane and Lysosomes
Authors: Xue Yun‐Wei , Hayata Atsushi , Itoh Hiroaki , Inoue Masayuki 
Published: September 2019

AbstractPolytheonamide B (1) is a linear 48‐mer natural peptide with alternating d‐ and l‐amino acid residues. Compound 1 forms conducting channels for monovalent ions and exhibits potent cytotoxicity against MCF‐7 cells. Previously, we reported that nanomolar concentrations of 1 induce plasma membrane depolarization and lysosomal pH disruption, which triggers apoptosis. Here, we report the cellular localization and biological action of a simplified synthetic analogue of 1, polytheonamide mimic 3. Compared with 1, the toxicity of 3 against MCF‐7 cells is 16 times weaker. Although its plasma membrane depolarization effect is only 3.6 times lower, more 3 (20‐fold) is required to neutralize lysosomal pH. Thus, the effective concentrations for lysosomal neutralization and cytotoxicity by 3 are comparable. These results strongly suggest that the activity of 3 against the lysosomal membrane is more important for apoptotic cell death than its effects on the plasma membrane, and provide valuable information regarding the unique behavior of polytheonamide‐based molecules.
Mass deworming for soil‐transmitted helminths and schistosomiasis among pregnant women: A systematic review and individual participant data meta‐analysis
Authors: Salam R. A. , Cousens S. , Welch V. , Gaffey M. , Middleton P. , Makrides M. , Arora P. , Bhutta Z. A. 
Published: September 2019

AbstractThe objective of the review is to use individual participant data (IPD) meta‐analysis to explore the effect of mass deworming during pregnancy. We developed a search strategy and searched the databases till March 2018. We included individually randomised controlled trials; cluster randomised controlled trials and quasi randomised studies providing preventive or therapeutic deworming drugs for soil transmitted helminthiases and schistosomiasis during pregnancy. All IPD were assessed for completeness, compared to published reports and entered into a common data spreadsheet. Out of the seven trials elgible for IPD, we received data from three trials; out of 8,515 potential IPD participants; data were captured for 5,957 participants. Findings from this IPD suggest that mass deworming during pregnancy reduces maternal anaemia by 23% (Risk ratio [RR]: 0.77, 95% confidence intreval [CI]: 0.73–0.81; three trials; 5,216 participants; moderate quality evidence). We did not find any evidence of an effect of mass deworming during pregnancy on any of the other outcomes. There was no evidence of effect modification; however these findings should be interpreted with caution due to small sample sizes. The quality of evidence was rated as moderate for our findings. Our analyses suggest that mass deworming during pregnancy is associated with reducing anaemia with no evidence of impact on any other maternal or pregnancy outcomes. Our analyses were limited by the availability of data for the impact by subgroups and effect modification. There is also a need to support and promote open data for future IPDs.
Thermal Properties of Ordered and Disordered DNA Chains: Efficient Energy Conversion
Authors: Ojeda Silva Judith Helena , Maiti Santanu K. 
Published: September 2019

AbstractConsidering the numerous possibilities of having suitable thermoelectric energy conversion at nano‐scale level, especially for molecular systems, in the present work we put forward a new proposal along this using a flat DNA segment as a functional element. It is modeled by coupling two chains to a form a two‐stranded ladder like geometry, with interactions to first neighbors, within the tight‐binding prescription. We critically investigate electrical and thermal properties of DNA molecule depending on the length of the system, temperature, molecule‐to‐lead coupling and the degree of (correlated) disorder. Our analysis might be helpful in analyzing thermoelectric signatures of correlated and uncorrelated disordered systems, and can be verified in laboratory.
Influence of Orientational Disorder on the Optical Absorption Properties of the Hybrid Metal‐Halide Perovskite CH3NH3PbI3
Authors: Martynow Miłosz , Głowienka Damian , Szmytkowski Jędrzej , Galagan Yulia , Guthmuller Julien 
Published: September 2019

AbstractAn experimental and theoretical investigation is reported to analyze the relation between the structural and absorption properties of CH3NH3PbI3 in the tetragonal phase. More than 3000 geometry optimizations were performed to reveal the structural disorder and identify structures with the lowest energies. The electronic structure calculations provide an averaged band gap of 1.674 eV, which is in excellent agreement with the experimental value of about 1.6 eV. The simulations of the absorption spectrum for three representative structures with lowest energy reproduced the absorption shoulders observed in the experimental spectra. These shoulders are assigned to excitations having similar orbital characters and involving transitions between hybridized 6s(Pb)/5p(I) orbitals and 6p(Pb) orbitals. The geometries of the three structures were analyzed and the effects of the inorganic frame and the CH3NH3+ cations on the absorption properties were estimated. It was found that both changes in the inorganic frame and the CH3NH3+ cations orientations impact the absorption spectra, by modifying the transitions energies and intensities. This highlights the role of CH3NH3+ cation in influencing the absorption properties of CH3NH3PbI3 and demonstrates that CH3NH3+ cation is one of the key elements explaining the broad and nearly constant absorption spectrum in the visible range.
A Sensitive Sensor Based on Single‐walled Carbon Nanotubes: Its Preparation, Characterization and Application in the Electrochemical Determination of Drug Clorsulon in Milk Samples
Authors: Rudnicki Konrad , Brycht Mariola , Leniart Andrzej , Domagała Sławomir , Kaczmarek Katarzyna , Kalcher Kurt , Skrzypek Sławomira 
Published: September 2019

AbstractWithin this paper, a glassy carbon electrode modified with single‐walled carbon nanotubes (SWCNTs−GCE) was prepared, and employed for the determination of clorsulon (Clo), which is a frequently used veterinary drug against common liver fluke. The comprehensive topographical and electrochemical characterizations of bare GCE and SWCNTs−GCE were performed by atomic force microscopy, electrochemical impedance spectroscopy, and cyclic voltammetry. Significantly enhanced electrochemical characteristics of SWCNTs−GCE toward a ferrocyanide/ferricyanide redox couple was observed when compared to bare GCE. Further, the prepared sensor was applied for the voltammetric determination of Clo, which was electrochemically investigated for the first time in this work. Voltammetric experiments were performed using square‐wave voltammetry with optimized parameters in phosphate buffer solution, pH 6.8, which was selected as the most suitable medium for the determination of Clo. The corresponding current at approx. +1.1 V increased linearly with Clo concentration within two linear dynamic ranges of 0.75–4.00 μmol L−1 (R2=0.9934) and 4.00–15.00 μmol L−1 (R2=0.9942) with a sensitivity for the first calibration range of 0.76 μA L μmol−1, a limit of detection of 0.19 μmol L−1, and a limit of quantification of 0.64 μmol L−1. The developed method was subsequently applied for quantitative analysis of Clo in milk samples with results proving high repeatability and recovery.
Performance of Hong Kong Liver Cancer staging system in patients of hepatocellular carcinoma treated with surgical resection: An Indian validation study
Authors: Patkar Shraddha , Parray Amir , Mahendra Balu , Kurunkar Sagar , Goel Mahesh 
Published: September 2019

AbstractBackgroundHong Kong Liver Cancer staging (HKLCS) system lacks external validation.Aims and MethodsWe conducted a study to validate the prognostic and clinical utility of HKLCS system in the patients with hepatocellular carcinoma (HCC) of heterogeneous etiologies treated with hepatic resection with curative intent at Tata Memorial Centre, Mumbai, India.ResultsA total of 144 patients underwent resection for HCC. Our patient cohort was comparable to the original developmental cohort in median age and gender distribution but differed in etiology, liver function status, and tumor venous invasion. On Kaplan‐Meier survival curve analysis for overall and disease‐free survival, we could achieve statistically significant separation of curves in both Barcelona Clinic Liver Cancer staging (BCLCS) and HKLCS staging systems (P < .000). Interstage discrimination between early and intermediate stages for survival was higher in HKLCS system (P value of .039 vs .091). The area under the receiver operating characteristic curve for the survival of BCLCS and HKLCS systems for the entire patient population was 0.66 and 0.60, respectively, which was not statistically significant (P = .31).ConclusionThe HKLCS system offered higher interstage discrimination power in the patients with HCC treated with resection and may be equally applicable to nonalcoholic steatosis‐related chronic liver disease and noncirrhotic patient population.