bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cloud service composition using minimal unsatisfiability and genetic algorithm
Authors: Ait Wakrime Abderrahim , Rekik Mouna , Jabbour Said 
Published: April 2019

SummaryThe software‐as‐a‐service layer of cloud computing has evolved much interest among the researchers in the academic and industry worlds. It is based on service‐oriented architectures and web service (WS) technology, which are used to offer a remotely accessible application. When a single WS is unable to satisfy all the customer's requirements, a WS composition (WSC) method is applied to connect together various available WSs for building distributed application, using discovery, compatibility checking, selection, and deployment steps. This paper has two‐fold contributions: The major one is the proposition of a new algorithm based on minimally unsatisfiable subset formal algorithm to compose WSs. This contribution ensures a faster WSC, which is prominent in an online context. The second contribution is the proposition of a new penalty‐based genetic algorithm to identify near‐optimal solutions whenever an exact one is not identified using our formal algorithm. Indeed, in some cases, many available WSs provide overlapping/identical functionality; in this context, the choice of participated services is given using quality of service. This work proposes a WSC ensuring to find out an exact or a near‐optimal solution according to the user need. A set of experimentations is applied to validate our contributions.
Crystal Structure Characterization, Independent Gradient Model Analysis, and Gas‐Phase‐Mediated Transformation of Nicosulfuron DMF Solvate and Hydrate
Authors: Chen Liang , Zhou Ling , Zhang Xia , Yang Yongfan , Zhang Shihao , Yang Wenchao , Xie Chuang , Hou Baohong , Bao Ying , Yin Qiuxiang 
Published: April 2019

AbstractThis review presents a comprehensive crystallographic study of nicosulfuron solvates and their transformation. N,N‐dimethylformamide solvate and hydrate are prepared and characterized by single‐crystal X‐ray diffraction. Although the crystal systems are different, their space conformations are quite similar. Independent gradient model simulation reveals that the nicosulfuron dimer structure is dominated by dispersion energy and the solvent molecules combine with the solute molecules by electrostatic energy. Dynamic vapor sorption is used for observation of the gas‐phase‐mediated transformation from the N,N‐dimethylformamide solvate to the hydrate, which is found to be dominated by the diffusion of water molecules and desorption of N,N‐dimethylformamide molecules.
Investigation of Perovskite Oxide SrCo0.8Cu0.1Nb0.1O3–δ as a Cathode Material for Room Temperature Direct Ammonia Fuel Cells
Authors: Zou Peimiao , Chen Shigang , Lan Rong , Tao Shanwen 
Published: April 2019

AbstractSingle‐phase perovskite oxide SrCo0.8Cu0.1Nb0.1O3–δ was synthesized using a Pechini method. X‐ray diffraction (XRD) analysis indicated a cubic structure with a=3.8806(7) Å. The oxide material was combined with active carbon, forming a composite electrode to be used as the cathode in a room temperature ammonia fuel cell based on an anion membrane electrolyte and NiCu/C anode. An open circuit voltage (OCV) of 0.19 V was observed with dilute 0.02 m (340 ppm) ammonia solution as the fuel. The power density and OCV were improved upon the addition of 1 m NaOH to the fuel, suggesting that the addition of NaOH, which could be achieved through the introduction of alkaline waste to the fuel stream, could improve performance when wastewater is used as the fuel. It was found that the SrCo0.8Cu0.1Nb0.1O3−δ cathode was converted from irregular shape into shuttle‐shape during the fuel cell measurements. As the key catalysts for electrode materials for this fuel cell are all inexpensive, after further development, this could be a promising technology for removal of ammonia from wastewater.
Simultaneous Mapping of Oxygen Reduction Activity and Hydrogen Peroxide Generation on Electrocatalytic Surfaces
Authors: Kolagatla Srikanth , Subramanian Palaniappan , Schechter Alex 
Published: April 2019

AbstractElectrochemical scanning probe microscopies have become valuable experimental tools, owing to their capability of capturing topographic features in addition to mapping the electrochemical activity of nanoscale oxygen reduction catalysts. However, most scanning probe techniques lack the ability to correlate topographic features with the electrochemical oxygen reduction and peroxide formation in real time. In this report, we show that it is indeed possible to construct high‐resolution catalytic current maps at an electrified solid–liquid interface by placing a specially made Au‐coated SiO2 Pt atomic force microscopy and scanning electrochemical microscopy (AFM–SECM) dual electrode tip approximately 4–8 nm above the reaction center. The catalytic current measured every 16 nm and high collection efficiency (≈90 %) of the reverse current of peroxide byproducts was also demonstrated with the help of the dual electrode tip. Simultaneous oxygen reduction and intermediate peroxide oxidation current mapping was demonstrated using this Au‐coated SiO2 Pt probe on two model surfaces, namely highly oriented pyrolytic graphite and Pt nanoparticles (NPs) supported on a glassy carbon surface.
Ectopic breast tissue lesion in axilla: Cytology report of two cases
Authors: Nigam Jitendra Singh , Garg Pooja , Talukder Shibojit 
Published: April 2019

AbstractEctopic breast tissue (EBT) predominantly seen along the primitive embryonic milk lines that extend from axilla to groin. Axillary breast tissue is one of the common variant of EBT seen in 2% to 6% of women. Phyllodes tumour in EBT is uncommon. The various cystic, inflammatory and neoplastic lesions may occur in EBT similar to breast counterpart. Therefore, EBT should be carefully investigated as it may affect the management of the patient. We report two cases (axillary phyllodes tumour and axillary fibroadenoma) of axillary EBT diagnosed on cytology.
Anti‐inflammatory effects of Vicenin‐2 on dextran sulfate sodium‐induced colitis in mice
Authors: Yin Yuti , Ye Lei , Niu Zhongbao , Fang Wenhui 
Published: April 2019

AbstractThe objective of the present work was to evaluate the anti‐inflammatory effects of Vicenin‐2 on dextran sulfate sodium (DSS)‐induced colitis model. Colitis was induced in C57BL/6J mice by administration of 2% DSS in drinking water for 7 days. In addition to DSS, Vicenin‐2 (50 mg kg−1/day−1) was administrated orally to the test group. The ulceration extent and severity were assessed macroscopically, histopathologically, and by disease activity index. The Vicenin‐2 treated group showed significant differences in physiological parameters including bodyweight, colon weight, and colon length, compared to DSS‐induced colitis group. In addition, Vicenin‐2 treatment effectively reduced stool consistency and bleeding scores. Myeloperoxidase (MPO) activity, expressions of pro‐inflammatory cytokines, and specific key inflammatory markers (iNOS and COX‐2) significantly increased in DSS‐induced colitis colon tissues. However, administration of Vicenin‐2 effectively reduced the MPO activity, attenuated the expression of pro‐inflammatory cytokines and key inflammatory markers, in DSS‐induced colitis mice. These results were comparable with sulfasalazine, an anti‐inflammatory drug used routinely for ulcerative colitis (UC). These findings suggest that Vicenin‐2 effectively suppresses DSS‐induced colitis by attenuating expressions of key inflammatory mediators and found to be an attractive therapeutic drug for treating UC.
Actomyosin contraction during cellularization is regulated in part by Src64 control of Actin 5C protein levels
Authors: Carter Tammy Y. , Gadwala Swetha , Chougule Ashish B. , Bui Anh P. N. , Sanders Alex C. , Chaerkady Raghothama , Cormier Nathaly , Cole Robert N. , Thomas Jeffrey H. 
Published: April 2019

SummarySrc64 is required for actomyosin contraction during cellularization of the Drosophila embryonic blastoderm. The mechanism of actomyosin ring constriction is poorly understood even though a number of cytoskeletal regulators have been implicated in the assembly, organization, and contraction of these microfilament rings. How these cytoskeletal processes are regulated during development is even less well understood. To investigate the role of Src64 as an upstream regulator of actomyosin contraction, we conducted a proteomics screen to identify proteins whose expression levels are controlled by src64. Global levels of actin are reduced in src64 mutant embryos. Furthermore, we show that reduction of the actin isoform Actin 5C causes defects in actomyosin contraction during cellularization similar to those caused by src64 mutation, indicating that a relatively high level of Actin 5C is required for normal actomyosin contraction and furrow canal structure. However, reduction of Actin 5C levels only slows down actomyosin ring constriction rather than preventing it, suggesting that src64 acts not only to modulate actin levels, but also to regulate the actomyosin cytoskeleton by other means.
Disaggregating the predictive effects of impaired psychosocial functioning on future DSM‐5 eating disorder onset in high‐risk female adolescents
Authors: Mehl Annette , Rohde Paul , Gau Jeff M. , Stice Eric 
Published: April 2019

AbstractObjectiveImpaired psychosocial functioning previously emerged as the only risk factor to predict future onset of each of the four Diagnostic and Statistical Manual of Mental Disorder (5th ed.) (DSM‐5) eating disorders. The goal of this follow‐up report was to refine understanding of this newly identified risk factor.MethodCombining data from women at risk for eating disorders because of body image concerns (N = 1,153, mean age = 18.5 years, SD = 4.2), we investigated which subdomain(s) and individual item(s) of psychosocial functioning (friends, family, school, and work) at baseline predicted onset of any eating disorder, using Cox regression (CRA) and classification tree analysis (CTA).ResultsPsychosocial impairment with friends, family, and at school, but not at work, significantly increased risk for disorder onset over 3‐year follow‐up in univariate models. A one‐unit increase in each domain raw score was associated with a 107, 22, and 43% increased hazard of eating disorder onset, respectively. Multivariate CRA found friends functioning, with a 92% increased hazard of disorder onset, contributed the strongest unique effect. CTA suggested that loneliness was the most potent risk factor with a threefold increased onset risk (eating disorder incidence for high vs. low scorers was 27 and 8%). Three friends functioning items and one school functioning item produced additional CTA branches.DiscussionResults refine understanding of the relation of psychosocial impairment to future onset of eating disorders, suggesting that peer functioning is the most critical. Data imply it would be useful to target young women with impaired psychosocial functioning in prevention programs.
Landscape patterns in top‐down control of decomposition: omnivory disrupts a tropical detrital‐based trophic cascade
Authors: Simon Troy N. , Binderup Andrew J. , Flecker Alex S. , Gilliam James F. , Marshall Michael C. , Thomas Steven A.  , Travis Joseph , Reznick David N. , Pringle Catherine M. 
Published: April 2019

AbstractDetrital‐based trophic cascades are often considered weak or absent in tropical stream ecosystems because of the prevalence of omnivorous macroconsumers and the dearth of leaf‐shredding insects. In this study, we isolate top‐down effects of three macroconsumer species on detrital processing in headwater streams draining Trinidad's northern mountains. We separated effects of different macroconsumers by experimentally manipulating their temporal access to isolated benthic habitat over the diel cycle. We found no evidence that omnivorous macroconsumers, including a freshwater crab (Eudaniela garmani) and guppy (Poecilia reticulata), increased leaf decomposition via consumption. By contrast, above a waterfall excluding guppies, the insectivorous killifish, Anablepsoides hartii, reduced the biomass of the leaf‐shredding insect Phylloicus hansoni 4‐fold, which consequently reduced leaf decomposition rates 1.6‐fold. This detrital cascade did not occur below the barrier waterfall, where omnivorous guppies join the assemblage and reduce killifish densities; here killifish had no significant effects on Phylloicus or decomposition rates. These patterns of detrital processing were also observed in upstream–downstream comparisons in a landscape study across paired reaches of six streams. Above waterfalls, where killifish were present, but guppies absent, leaf decomposition rates and Phylloicus biomass were 2.5‐ and ~35‐fold lower, respectively, compared to measurements below waterfalls. Moreover, the strength of top‐down control by killifish is reflected by the 20‐ and 5‐fold reductions in variability (±SE) surrounding mean Phylloicus biomass and leaf decomposition rates in upstream relative to downstream reaches where no top‐down control was detected. Findings show a clear, detrital‐based trophic cascade among killifish, a leaf‐shredding insect, and leaf decomposition rates. Results also show how omnivorous guppies disrupt this cascade by depressing killifish densities, thereby releasing invertebrate shredders from predation, and significantly increasing decomposition rates. Moreover, this combination of direct and indirect trophic interactions drives patterns in decomposition rates in stream networks at a landscape scale, resulting in significantly lower rates of decomposition above vs. below barrier waterfalls. Our findings reveal that omnivory can result in significant indirect effects on a key ecosystem process, illustrating the importance of these hidden trophic pathways in detrital‐based systems and suggesting that resource control in tropical systems may be even more complex than previously envisioned.
Minimization of Interferences in Flow Injection Amperometric Glucose Biosensor Based on Oxidation of Enzymatically‐produced H2O2
Authors: Karakaya Serkan , Dilgin Yusuf 
Published: April 2019

AbstractOne of the major problems in amperometric biosensors based on detection of H2O2 produced by enzymatic reaction between oxidase enzymes and substrate is the interference of redox active compounds such as ascorbic acid (AA), dopamine (DA) and uric acid (UA). To minimize these interferences, sodium bismuthate was used for the first time as an insoluble pre‐oxidant in the flow injection (FI) amperometric glucose biosensor at a Glucose oxidase (GOx) immobilized Pt/Pd bimetallic modified pre‐anodized pencil graphite electrode (p.PGE). In this context, these interfering compounds were injected into a flow injection analysis (FIA) system using an injector which was filled with NaBiO3. Thus, these interferents were converted into their redox inactive oxidized forms before reaching the electrode in the flow cell. While glucose was not influenced by the pre‐oxidant in the injector, the huge oxidation peak currents of the interferents decreased significantly in the biosensor. FI amperometric current time curves showed that the AA, DA and UA were minimized by 96 %, 86 %, and 98 % respectively, in the presence of an equivalent concentration of interferences in a 1.0 mM glucose solution. The proposed FI amperometric glucose biosensor exhibits a wide linear range (0.01–10 mM, R2=0.9994) with a detection limit of 2.4×10−3 mM. Glucose levels in the artificial serum and two real samples were successfully determined using the fabricated FI amperometric biosensor.
Aptamer functionalized magnetic graphene oxide nanocomposites for highly selective capture of histones
Authors: Chen Yuanbo , Jiang Bo , Hu Yechen , Deng Nan , Zhao Baofeng , Li Xiao , Liang Zhen , Zhang Lihua , Zhang Yukui 
Published: April 2019

AbstractThe binding coverage of aptamer was an important restricted factor for aptamer‐based affinity enrichment strategy for capturing target molecules. Herein, we designed and prepared aptamer functionalized graphene oxide based nanocomposites (GO/NH2‐NTA/Fe3O4/PEI/Au), and the coverage density of aptamer was high to 33.1 nmol/mg. The high aptamer coverage density was contributed to the large surface area of graphene oxide. The successive modification of Nα,Nα‐Bis(carboxymethyl)‐L‐lysine, magnetic nanoparticles, polyethylenimine, and Au nanoparticles ensured the histone purification with fast speed and high purity. Histones could be captured rapidly and specifically from nucleoproteins by our aptamer based purification strategy, while traditional acid‐extraction could not specifically enrich histones. Compared with traditional acid‐extraction method, rapid and efficient discovery of histones and their post‐translational modifications, such as several kinds of methylation at H3.1K9 and H3.1K27, were achieved confidently. It demonstrated that our aptamer functionalized magnetic graphene oxide nanocomposites have a great potential for histone analysis.
A fully portable microchip real‐time polymerase chain reaction for rapid detection of pathogen
Authors: Tong Rui , Zhang Lijuan , Song Qi , Hu Chuandeng , Chen Xuee , Lou Kai , Gong Xiuqing , Gao Yibo , Wen Weijia 
Published: April 2019

AbstractPoint‐of‐care detection for pathogen is of critical need for wide epidemic warning and medical diagnosis. In this work, we have designed and developed a fully portable and integrated microchip based real‐time polymerase chain reaction machine for rapid pathogen detection. The instrument consists of three functional components including heating, optical, and electrical modules, which are integrated into a portable compact box. The microchip is consumable material replaceable to meet various detection needs. Consequently, we demonstrated the outstanding performance of this portable machine for rapid detection of Salmonella and Escherichia coli O157:H7 with the advantage of time‐saving (∼25 min), less samples consumption, portability, and user‐friendly operation.
Predictive control based on occupant behavior prediction for domestic hot water system using data mining algorithm
Authors: Cao Sheng , Hou Shengya , Yu Lijun , Lu Jie 
Published: April 2019

AbstractDomestic hot water systems are a primary source of energy consumption in buildings, and present a promising future in terms of energy saving. Predictive control methods have been used to reduce energy consumption during an operation period. However, current methods lack consideration of occupant behavior, which significantly influences the prediction results. In this study, a data‐based predictive method is proposed to predict the shower behavior of occupants. A dataset was collected from seven occupants and was trained using support vector machine (SVM) to learn their showering habits. These results were used to predict the hot water demand. A comparative analysis shows that, in this way, the prediction results are more reliable under predictive control than predicting the hot water demand directly using SVM. A simulation of a domestic hot water system was then conducted. The results indicate that the proposed approach can reduce the heat loss from a hot water storage tank (ST) by up to 33% compared to a traditional control method, while maintaining a high assurance of the hot water supply (an insufficient hot water supply of less than 1%) with little change to the original system.
Single image defocus estimation by modified gaussian function
Authors: Hassan Haseeb , Bashir Ali Kashif , Abbasi Rashid , Ahmad Waqas , Luo Bin 
Published: April 2019

AbstractThis article presents an algorithm to estimate the defocus blur from a single image. Most of the existing methods estimate the defocus blur at edge locations, which further involves the reblurring process. For this purpose, existing methods use the traditional Gaussian function in the phase of reblurring but it is found that the traditional Gaussian kernel is sensitive to the edges and can cause loss of edges information. Hence, there are more chances of missing spatially varying blur at edge locations. We offer the repeated averaging filters as an alternative to the traditional Gaussian function, which is more effective, and estimate the spatially varying defocus blur at edge locations. By using repeated averaging filters, a blur sparse map is computed. The obtained sparse map is propagated by integration of superpixels segmentation and transductive inference to estimate full defocus blur map. Our adopted method of repeated averaging filters has less computational time of defocus blur map estimation and has better visual estimates of the final defocus recovered map. Moreover, it has surpassed many previous state‐of‐the‐art proposed systems in terms of quantative analysis.
Grape peel (Syrah var.) jam as a polyphenol‐enriched functional food ingredient
Authors: Amorim Frederico Lopes , de Cerqueira Silva Mariana Barros , Cirqueira Marina Gonçalves , Oliveira Roseane Santos , Machado Bruna Aparecida Souza , Gomes Raquel Gutierres , de Souza Carolina Oliveira , Druzian Janice Izabel , de Souza Ferreira Ederlan , Umsza‐Guez Marcelo Andrés 
Published: April 2019

AbstractIn this study, we evaluated the effects of the storage time on the physicochemical properties, bioactive compound content, and antioxidant capacity of jam prepared from grape peel extract to explore its potential as a supplementary food and/or functional ingredient. The ethanolic extract from Syrah var. grape peel exhibited high bioactive compound concentrations and antioxidant activity. The jam stability (prepared with 8.9% of extract) at 14°C was evaluated at 0, 15, 30, 45, and 60 days. The jam was found to contain high concentrations of polyphenolic compounds (137.0 ± 3.2 mg of gallic acid equivalent/100 g), total flavonoids (128.5 ± 23.0 mg of equivalent/100 g), and total anthocyanins (92.5 ± 4.0 mg of cyanidin equivalent/100 g). However, a large reduction in the flavonoid (70%–90%), anthocyanin (29%–35%), and phenolic (23%–30%) content was observed during storage. The free radical‐scavenging activity (DPPH−), ferric reducing antioxidant power (FRAP), and β‐carotene‐linoleic acid assays revealed the great antioxidant potential of the jam prepared from grape peel extract, which exhibited significant levels of radical‐neutralizing activity, especially as determined by the DPPH method with EC50 values ranging from 2.3 ± 0.1 to 3.9 ± 0.1 µg/ml. High R2 values (p > 0.90) were obtained for the correlation between the DPPH results and the concentrations of the compounds of interest. In summary, the high bioactive compound contents and antioxidant capacity of the jam produced from grape peel suggest that it may provide health benefits as a source of natural antioxidants upon incorporation to several food industry products.