bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survival analysis to evaluate associations between periodontal disease and the risk of development of chronic azotemic kidney disease in cats evaluated at primary care veterinary hospitals
Authors: Trevejo Rosalie T. , Lefebvre Sandra L. , Yang Mingyin , Rhoads Catherine , Goldstein Gary , Lund Elizabeth M. 
Published: March 2018

Abstract
OBJECTIVE To examine potential associations between periodontal disease (PD) and the risk of development of chronic azotemic kidney disease (CKD) among cats and determine whether the risk of CKD increases with severity of PD.
DESIGN Retrospective cohort study.
ANIMALS 169, 242 cats.
PROCEDURES Cats were evaluated ≥ 3 times at any of 829 hospitals from January 1, 2002, through June 30, 2013. Cats with an initial diagnosis of PD of any stage (n = 56,414) were frequency matched with cats that had no history or evidence of PD (112,828) by age and year of study entry. Data on signalment, PD, and other conditions potentially related to CKD were extracted from electronic medical records. Cox proportional hazards modeling was used to estimate the association of PD with CKD after controlling for covariates.
RESULTS PD was associated with increased risk of CKD; risk was highest for cats with stage 3 or 4 PD. Risk of CKD increased with age. Purebred cats had greater risk of CKD than mixed-breed cats. General anesthesia within the year before study exit and diagnosis of cystitis at any point prior to study exit (including prior to study entry) were each associated with increased CKD risk. Diagnosis of diabetes mellitus or hepatic lipidosis at any point prior to study exit was associated with decreased CKD risk.
CONCLUSIONS AND CLINICAL RELEVANCE The findings supported the benefit of maintaining good oral health and can be useful to veterinarians for educating owners on the importance of preventing PD in cats.
AUTEKOLOGI BEGONIA DI SEBAGIAN KAWASAN TAMAN NASIONAL GUNUNG MERAPI
Authors: Undaharta NKE. , Sutomo Sutomo 
Published: March 2018

Penelitian dilakukan pada bulan September 2013 di Taman Nasional Gunung Merapi, Yogyakarta dengantujuan untuk mengetahui data ekologi Begonia di habitat alaminya serta tumbuhan bawah yang ada di sekitarnya.Pengambilan sampel dilakukan dengan membuat plot ukuran 2 x 2 m secara purposive sampling. Data lingkunganyang diperoleh masing-masing plot pada habitat Begonia dianalisis menggunakan Canonical CorespondenceAnalysis (CCA) dengan program Canoco untuk mengetahui seberapa besar pengaruh faktor-faktor ini terhadapkeberadaan Begonia. Data kelimpahan (abudance) vegetasi ditabulasikan ke dalam format excel spreadsheet yangdiinput ke dalam software PRIMER. Data dilakukan pre-treatment dengan square root transformation kemudian dihitung matriks kemiripan atau resemblance matrix berdasarkan indeks kemiripan Bray-Curtis sebagai dasar analisis Non Metric Multidimensional Scaling ordination/NMDS untuk mengetahui sebaran kelimpahan Begonia.Sebanyak 3 jenis Begonia yang dapat ditemukan di sebagian kawasan Taman Nasional Merapi diantaranya Begoniamultangula Blume, B. hirtella Link dan B. tenuifolia Draynd. Begonia hanya dijumpai di Bukit Plawangan danBukit Pranajiwa. Tumbuh secara mengelompok pada ketinggian 1004-1164 m dpl. Tumbuh pada kemiringan lahan27-40%, pH tanah 6.6-6.9, kelembaban tanah 10-19%. Begonia memiliki preferensi asosiasi dengan ketinggiantempat dan kelembaban tanah. Sumbu altitude lebih signifikan berperan dalam distribusi Begonia di lokasi studidibandingkan sumbu lingkungan kelembaban tanah. Hasil penelitian ini diharapkan dapat memberikan informasiyang bermanfaat dalam melakukan aklimatisasi dan konservasi Begonia.
Bio-composite materials: a short review of recent trends, mechanical and chemical properties, and applications
Authors: YILDIZHAN Şafak , ÇALIK Ahmet , ÖZCANLI Mustafa , SERİN Hasan 
Published: March 2018

Recently, the
attraction on the bio-composite (known as green composites) materials has
significantly increased due to the potential of being substitute to
conventional materials used in manufacturing industries. Bio-composite
materials are produced with natural fibres or natural resins instead of
synthesized fibres (carbon, glass, etc fibres) or resins (poly vinyl alcohol, epoxy,
etc resins ). The bio-based fibres such as jute, sisal, flax, hemp, bamboo,
hair, wool, silk etc., are obtained from plants or animals. Also, natural matrix
materials such as natural rubber, polyester, etc., are produced from plants.
The advantages of bio-composites such as the ease of disposal and being able to
composted characteristics of bio-composites after the expiration date which is
not generally possible with conventional synthetic materials, being renewable,
sustainable have attracted many researcher. Furthermore, the comparable
mechanical properties of bio-composites make feasible for application to many
different products. This study reviews the, recent trends, mechanical and
chemical properties, and application of bio-composites in recent years.
Surface Composition of (99942) Apophis
Authors: Reddy Vishnu , Sanchez Juan A. , Furfaro Roberto , Binzel Richard P. , Burbine Thomas H. , Le Corre Lucille , Hardersen Paul S. , Bottke William F. , Brozovic Marina 
Published: March 2018

Abstract
On 2029 April 13, near-Earth asteroid (NEA) (99942) Apophis will pass at a distance of ∼6 Earth radii from Earth. This event will provide researchers with a unique opportunity to study the effects of tidal forces experienced by an asteroid during a close encounter with a terrestrial planet. Binzel et al. predicted that close flybys of terrestrial planets by NEAs would cause resurfacing of their regolith due to seismic shaking. In this work, we present the best pre-encounter near-infrared spectra of Apophis obtained so far. These new data were obtained during the 2013 apparition using the NASA Infrared Telescope Facility (IRTF). We found that our spectral data is consistent with previous observations by Binzel et al. but with a much higher signal-to-noise ratio. Spectral band parameters were extracted from the spectra and were used to determine the composition of the asteroid. Using a naïve Bayes classifier, we computed the likelihood of Apophis being an LL chondrite to be >99% based on mol% of Fa versus Fs. Using the same method, we estimated a probability of 89% for Apophis being an LL chondrite based on ol/(ol+px) and Fs. The results from the dynamical model indicate that the most likely source region for Apophis is the ν
6 resonance in the inner main belt. Data presented in this study (especially Band I depth) could serve as a baseline to verify seismic shaking during the 2029 encounter.
Multiple-component Decomposition from Millimeter Single-channel Data
Authors: Rodríguez-Montoya Iván , Sánchez-Argüelles David , Aretxaga Itziar , Bertone Emanuele , Chávez-Dagostino Miguel , Hughes David H. , Montaña Alfredo , Wilson Grant W. , Zeballos Milagros 
Published: March 2018

Abstract
We present an implementation of a blind source separation algorithm to remove foregrounds off millimeter surveys made by single-channel instruments. In order to make possible such a decomposition over single-wavelength data, we generate levels of artificial redundancy, then perform a blind decomposition, calibrate the resulting maps, and lastly measure physical information. We simulate the reduction pipeline using mock data: atmospheric fluctuations, extended astrophysical foregrounds, and point-like sources, but we apply the same methodology to the Aztronomical Thermal Emission Camera/ASTE survey of the Great Observatories Origins Deep Survey–South (GOODS-S). In both applications, our technique robustly decomposes redundant maps into their underlying components, reducing flux bias, improving signal-to-noise ratio, and minimizing information loss. In particular, GOODS-S is decomposed into four independent physical components: one of them is the already-known map of point sources, two are atmospheric and systematic foregrounds, and the fourth component is an extended emission that can be interpreted as the confusion background of faint sources.
Testing Off the Clock: Allowing Extended Time for All Students on Tests
Authors: Birkhead Susan F. 
Published: March 2018

Background:
Standardized time allotments are typically imposed for administration of nursing tests. There is little evidence to guide the determination of time allotment. When time allotted for tests is too limited, construct irrelevant variance in test scores may be introduced and the reliability of tests may be negatively impacted.

Method:
For test administration, we establish a standard time allotment and offer all students the option of extended time.

Results:
Many of the students use extended time, reporting that extended time reduces stress. Program outcomes have not been negatively affected. Data are provided to guide calculation of time allotment.

Conclusion:

Extended time may help relieve test anxiety and facilitate success for students with undiagnosed learning disabilities or non-native English speakers. Time allotment should be based on the item composition of tests using published mean item response times. Further research is needed. [
J Nurs Educ.
2018;57(3):166–169.]
Escape Room Recruitment Event: Description and Lessons Learned
Authors: Connelly Liane , Burbach Beth E. , Kennedy Colleen , Walters Lisa 
Published: March 2018

Background:
The U.S. nursing workforce is facing a severe shortage of professionals due to an anticipated retirement of more than 500,000 RNs in the next 5 years.

Method:
An Escape to Nursing event was created and delivered in a rural medical center college of nursing in the spring of 2017. This faculty team developed four distinct rooms that were designed with key nursing concepts and patient health conditions. Recruits worked in teams to solve the patient health care puzzle, which then enabled them to proceed to the next room.

Results:
Feedback was positive from the recruits, including comments about expanding the game to more health care scenarios and reaching out to more recruits. Additional recruitment may lead to better turnout of recruits.

Conclusion:

Linear, sequential formatting for the escape room game design is recommended for use with recruits into nursing. The use of escape rooms for recruitment is a positive activity. [
J Nurs Educ.
2018;57(3):184–187.]
RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
Authors: Sun Chenming , Chen Shi-You 
Published: March 2018

Abstract
Systemic sclerosis (SSc) is a multisystem autoimmune disorder that is characterized by inflammation and fibrosis in the skin and internal organs. Previous studies indicate that inflammatory cells and cytokines play essential roles in the pathogenesis of SSc; however, the mechanisms that underlie the inflammation-driven development of SSc are not fully understood. In this study, we show that response gene to complement 32 (RGC32) is abundantly expressed in mouse macrophages in the early stage of bleomycin-induced SSc. Importantly, RGC32 is required to induce the inflammatory response during the onset of SSc, because RGC32 deficiency in mice significantly ameliorates skin and lung sclerosis and inhibits the expression of inflammatory mediators inducible NO synthase (iNOS) and IL-1β in macrophages. RGC32 appears to be a novel regulator for the differentiation of classically activated macrophages (M1 macrophages). IFN-γ and LPS stimulation induces RGC32 expression in primary peritoneal macrophages and bone marrow–derived macrophages. RGC32 deficiency impairs the polarization of M1 macrophages and attenuates iNOS and IL-1β production. Mechanistically, RGC32 interacts with NF-κB proteins and promotes iNOS and IL-1β expression by binding to their promoters. Collectively, our data reveal that RGC32 promotes the onset of SSc by regulating the inflammatory response of M1 macrophages, and it may serve as a promising therapeutic target for treating SSc.
MTOR Suppresses Cigarette Smoke–Induced Epithelial Cell Death and Airway Inflammation in Chronic Obstructive Pulmonary Disease
Authors: Wang Yong , Liu Juan , Zhou Jie-Sen , Huang Hua-Qiong , Li Zhou-Yang , Xu Xu-Chen , Lai Tian-Wen , Hu Yue , Zhou Hong-Bin , Chen Hai-Pin , Ying Song-Min , Li Wen , Shen Hua-Hao , Chen Zhi-Hua 
Published: March 2018

AbstractAirway epithelial cell death and inflammation are pathological features of chronic obstructive pulmonary disease (COPD). Mechanistic target of rapamycin (MTOR) is involved in inflammation and multiple cellular processes, e.g., autophagy and apoptosis, but little is known about its function in COPD pathogenesis. In this article, we illustrate how MTOR regulates cigarette smoke (CS)–induced cell death, airway inflammation, and emphysema. Expression of MTOR was significantly decreased and its suppressive signaling protein, tuberous sclerosis 2 (TSC2), was increased in the airway epithelium of human COPD and in mouse lungs with chronic CS exposure. In human bronchial epithelial cells, CS extract (CSE) activated TSC2, inhibited MTOR, and induced autophagy. The TSC2–MTOR axis orchestrated CSE-induced autophagy, apoptosis, and necroptosis in human bronchial epithelial cells; all of which cooperatively regulated CSE-induced inflammatory cytokines IL-6 and IL-8 through the NF-κB pathway. Mice with a specific knockdown of Mtor in bronchial or alveolar epithelial cells exhibited significantly augmented airway inflammation and airspace enlargement in response to CS exposure, accompanied with enhanced levels of autophagy, apoptosis, and necroptosis in the lungs. Taken together, these data demonstrate that MTOR suppresses CS-induced inflammation and emphysema—likely through modulation of autophagy, apoptosis, and necroptosis—and thus suggest that activation of MTOR may represent a novel therapeutic strategy for COPD.
Caracterización mecánica y reológica de un hormigón autocompactante elaborado con finos de recuperación procedentes de la fabricación de mezclas asfálticas
Authors: Castillo Mingorance Juan Manuel , Martínez-Echevarría Romero María José , Rodríguez Montero José , López Alonso Mónica 
Published: March 2018

En el trabajo que se presenta, se estudia la valorización de un fíller de recuperación, procedente de plantas de fabricación de aglomerados asfálticos, para su uso en la elaboración de hormigones autocompactantes (HAC) con aplicaciones estructurales. En primer lugar, se ha caracterizado el fíller para determinar su aplicabilidad en este tipo de hormigones. Posteriormente se han diseñado hormigones autocompactantes con los requisitos que exige su aplicación estructural en una clase IIb de exposición ambiental. Se ha partido del método de dosificación de Okamura, modificando las proporciones hasta seleccionar, mediante su ajuste con amasadas de prueba, la dosificación más conveniente que cumpla los requisitos normalizados de autocompactabilidad. Una vez logradas las propiedades de autocompactabilidad, el trabajo se ha centrado en la evaluación de las características mecánicas del hormigón seleccionado, determinando, entre otras, las resistencias a compresión y tracción, el módulo de deformación, el coeficiente de Poisson y la fluencia. Como referencia, se ha elaborado otro HAC, con la misma dosificación que el seleccionado pero empleando en su confección un fíller comercial, con el fin de evaluar los efectos del fíller objeto de estudio. Finalmente se estudia el comportamiento de las armaduras embebidas en el seno de este hormigón mediante la determinación del contenido crítico de cloruros que provocaría una corrosión intolerable. Los resultados obtenidos hasta la fecha están indicando que el hormigón elaborado con el fíller de recuperación satisface plenamente los requisitos de autocompactabilidad exigidos por la normativa actual, si bien exige una mayor dosis de aditivo superplastificante para lograrla. Asimismo este hormigón ha alcanzado valores de resistencia superiores a los mínimos establecidos para su aplicación estructural, sin embargo, se han observado en él mayores deformaciones instantáneas y a largo plazo que en el hormigón de referencia. El umbral de cloruros determinado, cuyo valor ha resultado ser ligeramente superior al establecido para hormigones convencionales, permite predecir un comportamiento satisfactorio de este HAC frente a la corrosión del acero de las barras corrugadas.DOI:http://dx.doi.org/10.4995/HAC2018.2018.5320
Empleo de residuos de industria cementera y arrocera en micro-hormigón para paneles de viviendas de interés social en Uruguay
Authors: Rodriguez de Sensale Gemma Paula , Sabalsagaray Curuchet Blanca Stela , Boiani Casella Alba Gabriela 
Published: March 2018

Sistemas constructivos no tradicionales se están utilizando actualmente en Uruguay para construcción de viviendas de interés social con subsidio gubernamental. Tal es el caso de un sistema denominado Emmedue (M2) que se basa en el empleo de paneles auto-portantes formados por poliestireno expandido y mallas de acero cuya morfología de diseño les permite recibir micro-hormigón en en obra. En este sistema para el micro-hormigón se limita la granulometría de los agregados para permitir la proyección en el panel (en especial sobre el panel vertical y el inferior de la losa). El micro-hormigón proyectado en cada cara de los paneles verticales, no puede ser inferior a 3cm de espesor y la carpeta de compresión en los paneles losa no menor a 5cm, siendo exigida una resistencia mínima para este micro-hormigón de fck= 25 MPa a los 28 días de edad. La ceniza de cáscara de arroz y el polvo de electro-filtro de industria cementera son residuos muy abundantes en nuestro país que no tienen aplicación específica. Por eso en este trabajo primeramente a partir de un micro-hormigón tomado como referencia, se estudia la variación de la resistencia a compresión a los 28 días de edad cuando se realizan mezclas binarias sustituyendo 5, 10, 15, 20 y 25% de cemento por estos residuos. Luego se estudia la incidencia económica que se produce por el empleo de esos residuos en la construcción de viviendas dúplex de 2 y 3 dormitorios, basadas en el sistema de paneles mencionado manteniendo la resistencia a compresión del micro-hormigón no inferior a 25MPa. Los resultados alcanzados permiten concluir que si bien el polvo de electro-filtro baja la resistencia y la ceniza de cáscara de arroz la sube, en relación a la referencia, hay porcentajes óptimos produciendo beneficios económicos y medioambientales su empleo.DOI:http://dx.doi.org/10.4995/HAC2018.2018.5936
Superficial temporal artery flap for reconstruction of complex facial defects: A new algorithm
Authors: Elbanoby Tarek M. , Zidan Serag M. , Elbatawy Amr M. , Aly Gaber M. , Sholkamy Khallad 
Published: March 2018

Background A variety of island flaps can be based on the superficial temporal artery with variable tissue composition. They can be used for defect reconstruction, cavity resurfacing, facial hair restoration, or contracture release.
Methods Seventy-two patients underwent facial reconstruction using a superficial temporal artery island flap from October 2010 to October 2014. The defects had various etiologies, including trauma, burns, tumors, exposed hardware, and congenital causes. We classified the patients by indication into 5 groups: cavity resurfacing, contracture release, facial hair restoration, skin coverage, and combined. The demographic data of the patients, defect characteristics, operative procedures, postoperative results, and complications were retrospectively documented. The follow-up period ranged from 24 to 54 months.
Results A total of 24 females and 48 males were included in this study. The mean age of the patients was 33.7±15.6 years. The flaps were used for contracture release in 13 cases, cavity resurfacing in 10 cases, skin coverage in 17 cases, facial hair restoration in 19 cases, and combined defects in 13 cases. No major complications were reported. Conclusion: Based on our experiences with the use of superficial temporal artery island flaps, we have developed a detailed approach for the optimal management of patients with composite facial defects. The aim of this article is to provide the reader with a systematic algorithm to use for such patients.
Possible errors in pain treatment with ozone [abstract]
Authors: Tiron Stefan 
Published: March 2018

This presentation is made based on (more than) 3000 patient’s experience.

The pain treatment with ozone is an excellent one. So … why don’t we have 100% results?

WRONG DIAGNOSIS :
- Treatment of an irradiate pain like a local one: every pain in
• Upper limb (with no evident cause): must be treated like an irradiate cervical problem, and treated in cervical region.
• Lower limb ( with no evident cause ) : must be treated like an irradiate lombar problem and treated in lombar region
- Traumatical or surgical scars in cervical or abdominal region can explain cervical or lombar pain. The treatment must begin with subcutaneous ozone injections in the pericicatricial region.
- Pain given by chronic fatigue syndrome.
- Treatment in diseases when the ozone treatment is inefficient ( lombar stenosis, torticolis … )

TECHNICAL ERRORS:
- position of the needle ( paravertebral )
- wrong concentration of ozone
Advertisement call of Brachycephalus albolineatus (Anura: Brachycephalidae)
Authors: Bornschein Marcos R. , Ribeiro Luiz Fernando , Rollo Jr. Mario M. , Confetti André E. , Pie Marcio R. 
Published: March 2018

Background. Brachycephalus are among the smallest terrestrial vertebrates in the world. The genus encompasses 34 species endemic to the Brazilian Atlantic Rainforest, occurring mostly in montane forests, with many species showing microendemic distributions to single mountaintops. It includes diurnal species living in the leaf litter and calling during the day, mainly during the warmer months of the year. The natural history of the vast majority of the species is unknown, such as their advertisement call, which has been described only for seven species of the genus. In the present study, we describe the advertisement call of Brachycephalus albolineatus, a recently described microendemic species from Santa Catarina, southern Brazil.
Methods. We analyzed 34 advertisement calls from 20 individuals of B. albolineatus, recorded between 5–6 February 2016 in the type locality of the species, Morro Boa Vista, on the border between the municipalities of Jaraguá do Sul and Massaranduba, Santa Catarina, southern Brazil. We collected five individuals as vouchers (they are from the type series of the species). We used the note-centered approach sensu Köhler et al. (2017) to describe the advertisement calls of the species.
Results. Brachycephalus albolineatus have a long advertisement call of 40–191 s (mean of 88 s) composed of 7–26 notes (mean of 14 notes) emitted at a rate of 6–13 notes per minute (mean of 9 notes per minute) and at a note dominant frequency of 5–7 kHz (mean of 6 kHz). Advertisement calls are composed of isolated notes and note groups (two notes involved in each particular note group); the former is composed by one to three pulses (mean of 2.0) and the note groups by two or three pulses in each note (mean of 2.7). Most advertisement calls present both isolated notes and note groups, with a few cases showing only the former. Note groups are emitted invariably in the last third of the advertisement call. Most isolated notes escalate their number of pulses along the advertisement call (1 to 2, 1 to 3 or 2 to 3). Note duration of isolated notes varies from 0.002–0.037 s (mean of 0.020 s) and duration of note group vary from 0.360–0.578 s (mean of 0.465 s).
Discussion. Individuals increase the complexity of their calls as is proceeds, incorporating note groups and pulses per note. Intra-individual variation analysis also demonstrated that less structured advertisement calls (i.e. with notes with fewer pulses) are not stereotyped. It is possible that isolated notes and note groups could have distinct function, perhaps territorial defense and mating, respectively. We believe that using a note-centered approach facilitates comparisons with calls of congeners, as well as underscores the considerable differences in call structure between species in a single group and among species groups.