bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Chronic Kidney Disease and Poor Diagnostic Accuracy of Dipstick Proteinuria in Human Immunodeficiency Virus-Infected Individuals: A Multicenter Study in Japan
Authors: Yanagisawa Naoki , Muramatsu Takashi , Koibuchi Tomohiko , Inui Akihiro , Ainoda Yusuke , Naito Toshio , Nitta Kosaku , Ajisawa Atsushi , Fukutake Katsuyuki , Iwamoto Aikichi , Ando Minoru 
Published: September 2018

AbstractBackgroundChronic kidney disease (CKD) has become one of the common comorbid conditions affecting the human immunodeficiency virus (HIV) population. Human immunodeficiency virus-infected individuals are at increased risk of developing CKD, and they are likely to experience faster progression of renal dysfunction compared with HIV-uninfected individuals. Albuminuria represents not only kidney damage but also manifests metabolic syndrome and vascular dysfunction.MethodsWe conducted a multicenter, cross-sectional study involving 2135 HIV-infected individuals in Japan to test the prevalence of CKD and proteinuria/albuminuria. Urine sample was analyzed by both dipstick test and albumin-to-creatinine ratio (ACR) assay. Chronic kidney disease was classified according to the Kidney Disease Outcomes Quality Initiative (K/DOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. The diagnostic performance of dipstick test to detect albuminuria (ACR ≥30 mg/g) was evaluated.ResultsThe prevalence of CKD, evaluated by K/DOQI and KDIGO guidelines, was 15.8% and 20.4%, respectively. Age, total cholesterol level, prevalence of hypertension, diabetes mellitus, and hepatitis C infection tended to increase, whereas levels of hemoglobin, serum albumin, and CD4 cell count tended to decrease as CKD risk grades progressed. Proteinuria and albuminuria were present in 8.9% and 14.5% of individuals, respectively. Dipstick test ≥1+ to detect albuminuria had an overall sensitivity of 44.9% and specificity of 97.2%.ConclusionsThe KDIGO guideline may enable physicians to capture HIV-infected patients at increased risk more effectively. The sensitivity of dipstick proteinuria to detect albuminuria is so poor that it may not serve as an alternative in HIV-infected individuals.
WALL THICKNESS OPTIMISATION OF AN IONISATION CHAMBER FOR DIRECTIONAL DOSE EQUIVALENT RATE MEASUREMENT AT LOW AND MEDIUM PHOTON ENERGIES
Authors: Singh Sunil K , Kulkarni M S 
Published: September 2018

Abstract
A thin and plane wall ionisation chamber having 900 cc volume was designed and fabricated to study the calibration coefficient dependency on ionisation chamber wall thickness for directional dose equivalent rate (Ḣ′(d)) at various low and medium energy X-ray beam qualities. Optimised wall thickness was established through measurements to achieve a near flat energy response using the developed ionisation chamber. The measurement shows that in the energy range 12–213 keV, the average calibration coefficient for directional dose equivalent rate lies within ±10% for wall thickness 1.2 mg/cm2 and 480 mg/cm2 (4 mm poly methyl methacrylate) for skin and eye lens dose monitoring, respectively. The study could be useful for the estimation of skin and eye lens doses for the paramedical staff and patient during the interventional radiology and interventional cardiology procedures by monitoring the directional dose equivalent rate.
Prevalence of subclinical ketosis and production diseases in dairy cows in Central and South America, Africa, Asia, Australia, New Zealand, and Eastern Europe1
Authors: Brunner Nikolaus , Groeger Stephan , Canelas Raposo Joao , Bruckmaier Rupert M , Gross Josef J 
Published: September 2018

Abstract
Subclinical ketosis (SCK) and periparturient diseases considerably account for economic and welfare losses in dairy cows. The majority of scientific reports investigating the prevalence of SCK and production diseases are based on empirical studies conducted in Western Europe and North America. The present study surveyed the prevalence of SCK and production-related clinical diseases in early lactating cows in various countries across the world other than those in North America and Western Europe. Twelve countries of South and Central America (Argentina, Brazil, Chile, Colombia, Mexico), Africa (South Africa), Asia (Thailand, China), Eastern Europe (Russia, Ukraine), Australia, and New Zealand were assessed, and data from a total of 8,902 cows kept at 541 commercial dairy farms were obtained. A minimum of five cows per farm were blood sampled and examined once after parturition up to day 21 of lactation. Blood concentration of β-hydroxybutyrate was measured (threshold for SCK: 1.2 mmol/L), and the presence of production-related diseases such as milk fever, retained placenta, mastitis, metritis, displaced abomasum, lameness, and clinical ketosis was recorded. More than 95% of all cows were examined in their second week of lactation. Across all investigated countries, the SCK prevalence was 24.1%, ranging from 8.3% up to 40.1%. The prevalence of production-related diseases detected during the first 21 d of lactation was relatively low (&lt;5%). Calculated odds ratios did not indicate an elevated risk for production diseases in cows with SCK. Despite differences in production systems across countries and variation between individual farms within a region, the present study data on SCK prevalence align with observations in Western European and North American dairy herds. At the very early stage of sampling and clinical examination for detection of SCK, it cannot be excluded that certain production diseases such as displaced abomasum, lameness, and mastitis have developed later.
Self-perceived Impact of Glaucomatous Visual Field Loss and Visual Disabilities on Driving Difficulty and Cessation
Authors: Tam Alex L.C. , Trope Graham E. , Buys Yvonne M. , Yang Yelin , Shen Carl , Jin Ya-Ping 
Published: September 2018

Purpose:
To investigate if glaucoma severity and the presence of self-reported glare and difficulty with dark adaptation are associated with driving difficulty or cessation.

Patients and Methods:
Individuals with glaucoma, age 50+ and visual acuity in the better eye ≥20/50 were included. Glaucoma severity was defined by the visual field mean deviation (MD) in the better eye and was classified into 2 groups: mild (MD>−6 dB) and moderate/severe (MD≤−6 dB). Patient responses to the glare and dark adaptation subscales in Glaucoma Quality of Life-15 questionnaire were used to measure relevant visual disability. Associations were assessed utilizing prevalence ratios (PR).

Results:
A total of 99 participants (57% female) were included with 19% (19/99) reporting driving cessation. Patients with moderate/severe glaucoma when compared with mild glaucoma reported a significantly higher percentage of driving cessation (33% vs. 8%; P=0.002), presence of glare (27% vs. 6%; P=0.012), and difficulty with dark adaptation (31% vs. 10%; P=0.011).
Individuals with self-perceived difficulty with dark adaptation were about 4 times more likely than those without to have difficulty driving at night (adjusted PR=3.94; P<0.0001) or in poor driving conditions (adjusted PR=4.09; P=0.0002). Self-reported glare was associated with an increased risk of driving difficulty in poor driving conditions (PR=4.17; P=0.05).

Conclusions:
Patients with moderate/severe glaucomatous visual field loss reported significantly higher percentage of driving cessation, presence of glare and difficulty with dark adaptation. Difficulty with dark adaptation was significantly associated with difficulty driving at night or in poor driving conditions. Further studies are needed to confirm these findings.
Posttraumatic headache in pediatrics: an update and review
Authors: Blume Heidi K. 
Published: September 2018

Purpose of reviewHeadache following concussion and mild traumatic brain injury is very common in pediatrics. There is significant concern about appropriate management of acute and persistent headache following mild head injuries in children among affected youth, their families and care providers.Recent findingsThe current article will review definitions and diagnoses of posttraumatic headache (PTHA), recent research regarding risk factors for persistence of postconcussion symptoms and headaches, current recommendations for the evaluation of youth with PTHA, recent data regarding efficacy of treatment options for PTHA, and current recommendations for the treatment of acute and persistent PTHA.SummaryPTHA is common following concussion in pediatrics. Some of the most consistent risk factors for persistent symptoms following concussion include female sex, adolescent age, prior concussion with prolonged recovery, prior headache history and high number of acute symptoms, particularly migrainous symptoms, following concussion. There are few prospective studies of the treatment of PTHA in pediatrics; however, a recent study found that short-term use of ibuprofen for those with acute PTHA following concussion may be associated with lower risk of symptoms and better function 1 week after injury. Currently complete rest or cocooning following concussion is not recommended as it may actually be associated with longer recovery time; a gradual return to cognitive and physical activity appears to be most effective strategy but more study is needed.
Guideline Assessment Project: Filling the GAP in Surgical Guidelines
Authors: Antoniou Stavros A. , Tsokani Sofia , Mavridis Dimitrios , López-Cano Manuel , Antoniou George A. , Stefanidis Dimitrios , Francis Nader K. , Smart Neil , Muysoms Filip E. , Morales-Conde Salvador , Bonjer Hendrik Jaap , Brouwers Melissa C. 
Published: September 2018

Objective:
The aim of the study was to identify clinical practice guidelines published by surgical scientific organizations, assess their quality, and investigate the association between defined factors and quality. The ultimate objective was to develop a framework to improve the quality of surgical guidelines.

Summary Background Data:
Evidence on the quality of surgical guidelines is lacking.

Methods:
We searched MEDLINE for clinical practice guidelines published by surgical scientific organizations with an international scope between 2008 and 2017. We investigated the association between the following factors and guideline quality, as assessed using the AGREE II instrument: number of guidelines published within the study period by a scientific organization, the presence of a guidelines committee, applying the GRADE methodology, consensus project design, and the presence of intersociety collaboration.

Results:
Ten surgical scientific organizations developed 67 guidelines over the study period. The median overall score using AGREE II tool was 4 out of a maximum of 7, whereas 27 (40%) guidelines were not considered suitable for use. Guidelines produced by a scientific organization with an output of ≥9 guidelines over the study period [odds ratio (OR) 3.79, 95% confidence interval (CI), 1.01–12.66, P = 0.048], the presence of a guidelines committee (OR 4.15, 95% CI, 1.47–11.77, P = 0.007), and applying the GRADE methodology (OR 8.17, 95% CI, 2.54–26.29, P < 0.0001) were associated with higher odds of being recommended for use.

Conclusions:
Development by a guidelines committee, routine guideline output, and adhering to the GRADE methodology were found to be associated with higher guideline quality in the field of surgery.
A remorin from Nicotiana benthamiana interacts with the Pseudomonas type-III effector protein HopZ1a and is phosphorylated by the immune-related kinase PBS1
Authors: Albers Philip , Üstün Suayib , Witzel Katja , Kraner Max , Börnke Frederik 
Published: September 2018

AbstractThe plasma membrane is at the interface of plant-pathogen interactions and thus many bacterial type-III effector proteins (T3Es) target membrane-associated processes to interfere with immunity. The Pseudomonas syringae T3E is a host cell plasma membrane (PM)-localized effector protein that has several immunity associated host targets but also activates effector triggered immunity (ETI) in resistant backgrounds. Although HopZ1a has been shown to interfere with early defense signaling at the PM, no dedicated plasma membrane-associated HopZ1a target protein has been identified until now. We show here, that HopZ1a interacts with the PM-associated remorin protein NbREM4 from Nicotiana benthamiana in several independent assays. NbREM4 re-localizes to membrane sub-domains after treatment with the bacterial elicitor flg22 and transient overexpression of NbREM4 in N. benthamiana induces the expression of a subset of defense related genes. We can further show that NbREM4 interacts with the immune-related receptor-like cytoplasmic kinase PBS1 and is phosphorylated by PBS1 on several residues in vitro. Thus, we conclude that NbREM4 is associated with early defense signaling at the PM. The possible relevance of the HopZ1a/NbREM4 interaction for HopZ1a virulence and avirulence functions is discussed.
Translation in the “contact zone” between accounting and human resource management
Authors: Ejiogu Amanze Rajesh , Ejiogu Chibuzo 
Published: September 2018

PurposeThe purpose of this paper is to develop an understanding of the process through which ideas are translated across disciplines. It does this by focussing on how the idea that people are corporate assets was translated between the accounting and human resource management (HRM) disciplines.Design/methodology/approachThis paper is based on the interpretation of a historical case study of the travel of ideas between the accounting and HRM disciplines. Translation is used as an analytical lens as opposed to being the object of the study and is theorised drawing on insights from the Scandinavian Institutionalist School, Skopos theory and linguistic translation techniques.FindingsTranslation by individual translators involved the translator stepping across disciplinary boundaries. However, translation performed by interdisciplinary teams occurs in the “contact zone” between disciplines. In this zone, both disciplines are, at once, source and target. Ideas are translated by editing and fusing them. In both cases, translation is value laden as the motives of the translators determine the translation techniques used. Legitimacy and gravitas of the translator, as well as contextual opportunities, influence the spread of the idea while disciplinary norms limit its ability to become institutionalised. Also, differential application of the same translation rule leads to heterogeneous outcomes.Originality/valueThis is the first accounting translation study to use the theories of the Scandinavian Institutionalist School or indeed combine these with linguistic translation techniques. It is also the first study in accounting which explores the translation of ideas across disciplines.
Data-driven innovation: switching the perspective on Big Data
Authors: Trabucchi Daniel , Buganza Tommaso 
Published: September 2018

Purpose
The pervasive spread of digital technologies brought an incredible boost in data availability. Companies are dealing with massive amount of data that wait to be exploited. At the same time, scholars are providing different strategies and methods to help companies capture the value embedded in their data to foster innovation and improve the efficiency of existing processes. In these research studies, data are the by-product of something else, and they are a silent asset that needs to be exploited. What if data might be considered the final goal? The paper aims to discuss these issues.

Design/methodology/approach
The research is based on an exploratory multiple case study analysis, on the basis of three cases used as an illustration for new ideas. In particular, the gathered data are analyzed according to models previously presented in the literature review, building on and expanding them.

Findings
The research proposes a data-driven approach to innovation, offering a peculiar view of the innovation process. The trigger point is the need of data that let begin the entire development process of a complex system. In this perspective, the application that data are a by-product of the entire innovation process and not the primary output is peculiar since the vast majority of the literature consider data as the by-product of the primary product.

Research limitations/implications
Future research is needed to assess the replicability of the model outside the mobile app industry and to measure its performances. Nevertheless, this paper provides insights both for scholars and managers, enlarging the discussion on digital innovation and digital business models.

Practical implications
The results provide a development process to foster innovation relying on the need of data as the trigger point, guiding entrepreneurs and managers in the building process of the entire digital system.

Originality/value
Previous research studies often considered Big Data (BD) in innovation as a way to enlarge the current product offer or to make the innovation process more effective or efficient; this paper changes the perspective by considering BD as the trigger and the enabler of the entire digital innovation process.
Boundary integration and innovative work behavior among nursing staff
Authors: Yasir Muhammad , Majid Abdul 
Published: September 2018

PurposeThe purpose of this paper is to investigate the impact of boundary integration (BI) on innovative work behavior (IWB) of nursing staff. Furthermore, in order to understand the constructive role of BI, this study also examines the mediating role of work-to-family enrichment (WFE) and moderating role of co-worker and supervisor support.Design/methodology/approachData were collected from 786 nurses and 144 doctors (nurse supervisors) through self-administered questionnaires from public sector hospitals in Pakistan. Descriptive statistics, correlation, Baron and Kenny approach (Causal steps approach), PROCESS Macro (Normal Test Theory) developed by Hayes and hierarchical regression approaches were used to analyze the collected data that provide several interesting results for the formulated hypotheses.FindingsResults indicated that BI among nursing staff is positively related to doctors’ rating of innovative behaviors. Moreover, WFE mediates the relationship of BI and IWB. Furthermore, the results also confirmed that the relationship between BI and IWB is stronger among those nurses who frequently received support from co-workers and supervisors.Originality/valueEmployees’ involvement in innovative work is of crucial importance for organization’s strength, especially in health care sector. Although researchers have identified various antecedents of nurses’ IWB, however, it is still unclear how BI influences IWB. Moreover, this study focuses on another important element of workplace support and argues that nurses who can successfully manage work and family matters through the integration of boundaries have greater opportunities to achieve enrichment and respond more effectively to demonstrate IWB.
Understanding undergraduates’ money management behaviour: a study beyond financial literacy
Authors: Bamforth Jill , Jebarajakirthy Charles , Geursen Gus 
Published: September 2018

Purpose
The money management behavior of undergraduates determines their smooth transition into adulthood. Economic, social and psychological factors also affect undergraduates’ money management behavior. Therefore, the purpose of this paper is to investigate how undergraduates manage and respond to economic, social and psychological factors affecting their money management behavior, and to examine whether this response changes as they make progress in their degree.

Design/methodology/approach
Adopting a qualitative exploratory approach, this study examined Australian undergraduates as they face many challenges to their money management behavior. The data were collected using six focus group discussions, held in three Australian universities, in which 47 undergraduates participated.

Findings
The findings have shown that their approach to manage spending, income, saving, peer relationships and stress changes as they make progress in their degree. However, they shared similar approaches to investment, followed parental money management advice and used technology for cost reduction, irrespective of the progress in their degree.

Research limitations/implications
This study was conducted with the data collected from a relatively small sample of respondents and was limited only to undergraduates. Moreover, this study was conducted in Australia, indicating that some of the results might be specific to the Australian context.

Practical implications
The findings of this study can be utilized by governments, financial institutions, educational institutions and parents who are interested in inculcating prudent money management behavior in undergraduates.

Originality/value
This study extends the scope of the literature beyond financial literacy, and has shown how undergraduates respond to economic, social and psychological aspects relating to money management behavior and how these responses vary as they make progress in their degree. This study has applied a qualitative exploratory approach, in contrast to quantitative methods which have generally been applied for studies relating to undergraduates’ money management behavior.
Type and wearing method-dependent COP and muscle fatigue measurement of baby carriers for the development of smart baby carriers
Authors: Lee Heeran , Hong Kyung Hwa 
Published: September 2018

Purpose
The purpose of this paper is to investigate how the center of pressure (COP) changes depending on the type and wearing method of baby carriers, which is fundamental research for the development of smart baby carriers. In addition, the most comfortable and least burdensome type and method of wearing baby carriers is suggested.

Design/methodology/approach
The COP and muscle fatigue were measured depending on the three types and wearing method of baby carriers. And then, the subjective stability, comfort, and fatigue were analyzed.

Findings
The results of this study show that horizontal changes to the COP are greater and when baby carriers are worn loosely, subjective comfort is worse. Furthermore, when the shoulder straps are worn loosely, the center of mass moves downwards, lowering the muscle fatigue of the shoulders, but greatly raising the muscle fatigue of the waist and thighs. Comparison of the shapes of baby carriers showed that X-type produced greater muscle fatigue in the shoulders, waist, and thighs, as well as greater subjective fatigue in the shoulders. However, subjective fatigue in the waist decreases when baby carriers without waist support are worn.

Originality/value
It is expected that changes in COP values based on the type and method of wearing baby carriers will be applied as fundamental data for the development of automatic-adjusting smart baby carriers that prevent muscular pain and concentrated pressure.