bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genesis and mineralization age of the quartz‐vein‐type scheelite deposits in Eastern Yanbian, Northeast China: Constraints on the regional tectonic setting
Authors: Chen Cong , Ren Yun‐sheng , Wu Tao‐tao , Yang Qun , Shang Qing‐qing 
Published: February 2019

The Eastern Yanbian area, Northeast China is tectonically located in the easternmost margin of the Xing'an Mongolian Orogenic Belt, which is a key area for providing important evidence of mineral deposits to constrain the tectonic evolution of the Paleo‐Asian Ocean. Five quartz‐vein‐type scheelite deposits have been identified in the eastern Yanbian area. These deposits are hosted within the late Palaeozoic metamorphic and granitic rocks and form under the identical hydrothermal mineralization. Zircon U–Pb ages and whole‐rock geochemistry of the ore‐hosting biotite granite and Sm–Nd ages of scheelite crystals within quartz veins are presented in this paper. Zircon U–Pb dating of the biotite granite yields a weighted mean age of 251.9 ± 2.2 Ma (mean standard weighted deviation (MSWD) = 4), and Sm–Nd dating of scheelite samples yields an isochron age of 251.7 ± 2.9 Ma (MSWD = 0.87), which constrains the scheelite mineralization in Eastern Yanbian to the late Permian. Our results, integrated with published geochronological data, indicate three periods of Phanerozoic W mineralization in Northeast China, (a) Cambrian, (b) late Permian (this work), and (c) Jurassic. Geochemical data reveal that the biotite granite is a calc‐alkaline I‐type granite, and it exhibits enrichment in large‐ion lithophile and light rare earth elements and depletion in high‐field‐strength and heavy rare earth elements (especially in Nb and Ta), consistent with the characteristics of arc magma. The subduction‐related biotite granite intrusion and quartz‐vein‐type scheelite mineralization together indicate that the Paleo‐Asian Ocean had not closed before the late Permian in the Eastern Yanbian area, and its final closure occurred in the Early‐Middle Triassic. The late Permian subduction of the Paleo‐Asian Ocean induced the partial melting of the lower crust, thus forming the magmatic arc activity and related quartz‐vein‐type scheelite mineralization, which clearly justifies the proposed tectonic–metallogenic model.
Evaluation of dalbavancin on length of stay in acute bacterial skin and skin structure infections
Authors: Jones Bruce M. , Hersey Roby , Taylor Colleen , Bland Christopher M. 
Published: February 2019

PurposeAcute bacterial skin and skin structure infections (ABSSSI) are common reasons for hospital admission. A pathway to shift care to the outpatient setting sooner could decrease length of stay (LOS). Our not‐for‐profit community health system has developed a novel practice of partnering with hospitalists as part of a multidisciplinary early discharge of hospitalized patients with dalbavancin for ABSSSI. The primary purpose of this study was to evaluate outcomes associated with this process.MethodsThis was a retrospective evaluation of an ongoing, prospective process between March 2016 and March 2017. The process involves the hospitalist or infectious diseases pharmacist evaluating patients as possible candidates for dalbavancin therapy. Patients were included if their infection was consistent with cellulitis, abscess, or post‐operative wound infection and they received dalbavancin immediately after discharge from the hospital. The primary outcome was hospital LOS with secondary outcomes of direct cost per case and 30‐day readmission rate. Hospital LOS and 30‐day readmission rate were benchmarked to national averages and internal data from the same time frame the year prior.ResultsForty four patients were identified who had received dalbavancin during the time period and met criteria for study inclusion. For the primary outcome of hospital LOS, patients discharged to receive dalbavancin had a mean LOS of 4.3 days similar to published national average (4.95 days in 2011) and lower than internal data (8 days). For secondary outcomes, mean total direct cost per case was $2989 and five patients (11.4%) were readmitted within 30 days similar to published national (16%) and internal data (8.6%).ConclusionPatients discharged to receive dalbavancin had a LOS and overall 30‐day readmission rate below published national data for ABSSSI. Further study is needed to evaluate this process as an effective means to shorten LOS in the management of ABSSSI.
Ultrastructure of the scolex of Orygmatobothrium schmittii (Cestoda: Phyllobothriidea)
Authors: Mutti Leonardo Damian , Ivanov Verónica A. 
Published: February 2019

AbstractThe ultrastructure of the scolex of Orygmatobothrium schmittii (Cestoda: Phyllobothriidae) was studied using histochemistry, scanning, and transmission electron microscopy. The central bothridial structure resulted in a glandulomuscular organ formed by a mass of syncytial glands and radial muscles, with glycoprotein secretions potentially adhesive. Among the sensory receptors found on the scolex, a particular type was found surrounding the glandulomuscular organ, which might be related in the regulation of the secretions. The internal structure of the microtriches revealed a diversity of configurations according to their morphotype and distribution on the scolex. Microtriches with larger caps are thought to be useful for attachment purposes. In addition, the thick bounding membranes of the attachment organs and the circular musculature in the bothridia, seem to aid to the attachment of the scolex to the mucosa of the host.
Bracketing of premature beats arising from the left bundle branch
Authors: Park Jeong‐Wook , Ha Yeong‐Woong , Kim Sung‐Hwan , Oh Yong‐Seog 
Published: February 2019

AbstractFascicular premature ventricular contractions (PVCs) can arise from anywhere in the His Purkinje system, but PVCs originating from the left bundle branch (LBB) are rarely reported. We report the case of PVC arising from the LBB, and also describe the electrophysiological features that might indicate the bracketing of the fascicular PVC focus.
Effects of additional ablation of low‐voltage areas after Box isolation for persistent atrial fibrillation
Authors: Kumagai Koichiro , Toyama Hideko , Zhang Bo 
Published: February 2019

AbstractBackgroundPrevious studies reported that ablation of low‐voltage areas (LVAs) after pulmonary vein isolation (PVI) improves the success rate in persistent atrial fibrillation (PerAF) patients with LVAs. However, the need for LVA ablation in addition to the posterior left atrial isolation, Box isolation (BOXI), for PerAF is unclear. We evaluated the effects of LVA ablation after BOXI for PerAF with LVAs.MethodsIn 115 patients with PerAF (75 longstanding PerAF), LA voltage maps were created during sinus rhythm after PVI. Subsequently, BOXI was performed. In 61 patients without LVAs (<0.5 mV), BOXI alone was performed. Fifty‐four patients with LVAs were randomly assigned to BOXI plus LVA ablation (33 patients) or BOXI alone (21 patients).ResultsThe rate of AF termination or cardioversion after BOXI was significantly higher than that after PVI (100% vs 88%, P < 0.001). The inducibility of atrial tachyarrhythmia after BOXI was significantly lower than that after PVI (27% vs 100%, P < 0.001). During 24 ± 9 months of follow‐up after a single procedure, atrial tachyarrhythmia‐free rate in the patients with LVAs, was significantly lower than that without LVAs (65% vs 82%, P = 0.043). However, the success rate was not significantly different between the BOXI plus LVA ablation group and the BOXI alone group of patients with LVAs (67% vs 62%, P = 0.722).ConclusionBOXI facilitates AF termination and its non‐inducibility. Among patients with PerAF, BOXI alone may be adequate in cases without LVAs. Although cases with LVAs have higher risk of AF recurrence, additional LVA ablation does not improve the outcomes much.
Development of a Stimuli‐Responsive Gemini Zwitterionic Viscoelastic Surfactant for Self‐Diverting Acid
Authors: Zhang Wenlong , Mao Jincheng , Yang Xiaojiang , Zhang Heng , Yang Bo , Zhang Zhaoyang , Zhang Yang , Zhao Jinzhou 
Published: February 2019

AbstractA Gemini zwitterionic viscoelastic surfactant named self diverting acid ‐ gemini sulfonated surfactant (SDA‐GS), which has double quaternary ammonium groups, double sulfonate groups, and two hydrophobic tails, was synthesized from oleylamidopropyl dimethylamine, 1,3‐propanesultone, and 2, 2‐bis(bromomethyl)propane‐1, 3‐diol. The viscosity of an SDA‐GS aqueous solution varies with acid and calcium chloride concentrations. With a decrease in the HCl concentration, the viscosity of the acid solution prepared with SDA‐GS increases to a maximum value, followed by a decrease, which results from the aggregation of the surfactant into wormlike micelles and the following disaggregation. Calcium ions generated by the reaction of acid and calcium carbonate can enhance the aggregation of the surfactant to increase the peak viscosity of the acid solution. The peak viscosity of the acid solution prepared by 5 wt.% SDA‐GS without calcium ions could only reach 73.2 mPa.s when the HCl concentration was 4 wt.%, but that of the acid solution with calcium carbonate powder added could reach over 200 mPa.s when the HCl concentration was consumed to 4 wt.% and the calcium chloride concentration 21.6 wt.%. The viscoelastic measurements proved that calcium ions can drive the growth of the wormlike micelle. The acid and Ca2+ response of SDA‐GS can be applied in self‐diverting acid to improve the acid displacement in the heterogeneous reservoir. Experimental evaluation showed that the acid solution prepared by SDA‐GS and the selected corrosion inhibitor showed a good corrosion inhibition performance and a viscosity variation that makes it an efficient self‐diverting acid. The spent acid (21.6 wt.%) with 4 wt.% HCl retained high viscosity over 80 mPa.s at a 170 s−1 shearing rate and at 120°C after 90 min. The parallel core flood tests to simulate in situ application of SDA‐GS acid showed that the permeability improvement ratios (K1/K0) of the cores could reach 182.3 and 278.4 at 60 and 90°C, respectively.
Identification and characterization of forced degradation products and stability‐indicating assay for notoginsenosidefc by using UHPLC‐Q‐TOF‐MS and UHPLC‐MS/MS: Insights into stability profile and degradation pathways
Authors: Ma Chao , Guan Huida , Ju Zhengcai , Li Shuping , Deng Gang , Zhang Yunpeng , Lin Qiyan , Cheng Xuemei , Yang Li , Wang Zhengtao , Wang Changhong 
Published: February 2019

AbstractNotoginsenoside Fc, a protopanaxadiol‐type saponin, shows multi‐pharmacological activities. Chemical stability evaluation plays a crucial role in drug development. In this study, the forced degradation behavior of Notoginsenoside Fc was investigated under hydrolytic and oxidative conditions. A specific ultra high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry was developed for the separation, identification, and characterization of the degradation products of Notoginsenoside Fc. Fifty potential degradation products were formed via deglycosylation, dehydration, hydration, isomerization, side‐chain cleaving, oxidation, and superoxidation. Notoginsenoside Fc was subjected to different pH solutions, temperatures, and time periods to assess its stability. A sensitive ultra high performance liquid chromatography‐tandem mass spectrometry was developed for the quantification of Notoginsenoside Fc, notoginsenoside ST‐4, notoginsenoside Ft1, and relative quantification of notoginsenoside Ft2, 20(R)‐notoginsenoside Ft2, notoginsenoside SFt3, and notoginsenoside SFt4. The assay was linear over the concentration range (R2 > 0.997) with the lowest limit of quantification of 0.02 μg/mL for Notoginsenoside Fc, Notoginsenoside ST‐4, and Notoginsenoside Ft1. The intra‐day precision, inter‐day precision, and accuracy of the three analytes were within accepted levels. The degradation kinetics of Notoginsenoside Fc in pH 1 and 3 solutions fits to first‐ and second‐order kinetics, respectively. The degradation of Notoginsenoside Fc is pH‐, temperature‐, and time‐dependent.
Exploring the role of atmospheric cues and authentic pride on perceived authenticity assessment of museum visitors
Authors: Loureiro Sandra Maria Correia 
Published: February 2019

AbstractThe current study aims to investigate the relationships between authenticity and related constructs, such as atmospheric cues, place attachment, authentic pride, and word of mouth. We tested the proposed model using a sample of 387 visitors who experienced the National Museum of Ancient Art in Lisbon, Portugal. Atmospheric cues revealed to be a more important driver to perceived authenticity than place attachment. Perceived authenticity seems to be a better predictor of authentic pride than word of mouth. The results allow to highlight several implications and suggestions for further research.
Implementation of the Current Dystonia Classification from 2013 to 2018
Authors: Sasikumar Sanskriti , Albanese Alberto , Krauss Joachim K. , Fasano Alfonso 
Published: February 2019

ABSTRACTBackgroundThere is a discrepancy in the way dystonia is classified in the literature, as articles continue to reference the old criteria or fail to use the 2013 criteria correctly.MethodsWe performed a systematic review of the dystonia literature and distinguished between studies that use the new classification correctly, made errors in implementing the new classification, or continued to use the old classification methods.ResultsOf the 990 articles included in the study, 59.8% used the classification correctly, 31.3% used mixed terminology, and 8.9% continued to use the old classification. Articles relating to surgery were significantly less likely to use the new classification correctly. There is an upward trend in the annual rate of articles properly referencing the new classification.ConclusionsThe 2013 classification has been well received in scientific literature, and more studies are adapting to its use.
Home Parenteral and Enteral Nutrition During Natural Disasters: A Guide for Clinicians and Consumers
Authors: Ireton‐Jones Carol , Nishikawa Kari , Nishikawa Reid 
Published: February 2019

AbstractNatural disasters are most often weather related but can also be unrelated to weather. Either way, these disrupt “normal” life for a short or extended period of time. When someone depends on electricity, clean water, and transportation services for life‐sustaining therapies such as home nutrition support, it is important to have a plan in place—even if it is never used. Understanding supply needs, access to home utilities, and when to change location should be discussed, determined, and defined. In this article, the authors strive to provide this information for home parenteral and enteral nutrition support patients (consumers), caregivers, and clinicians.
Fundamental problems with pediatric adaptive dosing of carboplatin using nuclear‐medicine‐based estimates of renal function
Authors: Adamson Peter C. , Veal Gareth J. , Womer Richard B. , Meany Holly J. , Bernhardt M. Brooke , Frazier A. Lindsay , Balis Frank M. 
Published: February 2019

AbstractBackgroundCarboplatin is often adaptively dosed based on glomerular filtration rate (GFR), usually estimated by nuclear medicine tests. At least five pediatric adaptive dosing formulas have been developed. In an effort to standardize dosing in Children's Oncology Group protocols, we explored methodologic variation in GFR estimation and adaptive‐dosing formula performance.ProcedureNuclear medicine GFR data from published series of ≥100 children with cancer were compared. Data from patients for whom body surface area, weight, GFR, and tracer half‐life were available were used to compare formulas.ResultsDifferences in methods used to estimate GFR in children with cancer resulted in highly variable population results, with median GFRs ranging from 96 to 150 mL/min/1.73m2. The choice of adaptive formula had a major impact on calculated dose. When targeting an area under the curve of 7.9 mg/mL • min, the median difference between the formula yielding the lowest and highest carboplatin dose for individual subjects was 289 (range 96‐1 737) mg/m2.ConclusionsWide variation in GFR obtained with nuclear‐medicine‐based tests in children with cancer primarily results from systematic methodologic errors. Formulas for calculating carboplatin dose produce additional and substantial variation that may place children with cancer at unnecessary risk for excessive toxicity or underdosing. These findings indicate a need for the development of a uniform, validated method for GFR determination in children that should be utilized in all centers. Currently, adaptive dosing of carboplatin based on GFR has serious limitations and in most clinical settings should arguably not be used in place of body‐surface‐area‐based dosing.
Rapid thermal processing of cost‐effective contacts for silicon solar cells
Authors: Unsur Veysel , Klein Talysa , van Hest Maikel F.A.M. , Al Jassim Mowafak , Ebong Aba 
Published: February 2019

AbstractThis paper reports on the investigation of rapid thermal processing (RTP) of contacting the Al‐BSF solar cell with Ag, Cu, and Ni in conjunction with aerosol printing technique. The study showed a liftoff and delamination, respectively, for the bi and tri stack layers of Ag frit/Ni and Ag frit/Ni/Cu fired above 790°C peak firing temperature. The 770°C peak firing temperature gave excellent electrical performance for both bi and tri stack layer contacts, which is not favorable to forming thick back surface field (BSF) required for high open circuit voltage (VOC). This suggests that the bilayer and trilayer contacts involving Ag frit are limited to low peak firing temperature, but Ni frit, on the other hand, showed a wider firing temperature range. This is supported by low reverse saturation current density (J02) of 1.1 × 10−11 A/cm2 and high shunt resistance (RSH) of 5750 Ω·cm2 for the Ni frit fired at 800°C peak firing temperature. More so, the adhesion of Ni Frit to silicon is better than Ag counterpart as evidenced in the SEM micrograph. Thus, by adopting RTP Ni/Cu contacts, the cost of metallization of solar cell can be dropped from 35% of total processing cost to only 5% to 6%, which is approximately 30% drop in the total cost of processing.
Completing the Immunological Fingerprint by Refractory Proteins: Autoantibody Screening via an Improved Immunoblotting Technique
Authors: Moritz Christian P. , Tholance Yannick , Rosier Carole , Reynaud‐Federspiel Evelyne , Svahn Juliette , Camdessanché Jean‐Philippe , Antoine Jean‐Christophe 
Published: February 2019

PurposeIdentifying autoantigens of serological autoantibodies requires expensive methods, such as protein microarrays or IP+MS. Thus, sera are commonly pre‐screened for interesting immunopatterns via immunocytochemistry/immunohistochemistry. However, distinguishing immunopatterns can be difficult and intracellular antigens are less accessible. Therefore, a simple and cheap immunoblot screening able to distinguish immunopatterns and to detect refractory proteins is presented.Experimental DesignFive steps of immunoblotting‐based autoantigen screening are revised: (1) choice of protein source, (2) protein extraction, (3) protein separation, (4) protein transfer, (5) antigen detection. Thereafter, 52 patients' sera with chronic inflammatory demyelinating polyneuropathy (CIDP) and 45 controls were screened.ResultsThe protein source impacts the detected antigen set. Steps 2‐4 can be adapted for refractory proteins. Furthermore, longitudinal cutting of protein lanes saves ≥75% of time and material and allows for exact comparison of band patterns. As the latter are individually specific and temporarily constant, we call them “immunological fingerprints”. In a proof‐of‐principle, a 155 kDa immunoband was detected with two anti‐neurofascin‐155‐positive CIDP sera and two further immunobands (120/220 kDa) specific to a subgroup of 3‐6 of 52 CIDP patients.Conclusions and Clinical RelevanceAdapted immunoblotting is a cheap and simple method for accurate serum screening including refractory and intracellular antigens.
Corporate social responsibility and the role of rural women in sustainable agricultural development in sub‐Saharan Africa: Evidence from the Niger Delta in Nigeria
Authors: Uduji Joseph Ikechukwu , Okolo‐Obasi Elda N. , Asongu Simplice A. 
Published: February 2019

AbstractLow productivity among female farmers when compared with their male counterparts is considered an outcome of limited access to agricultural land and inputs. The objective of this investigation was to assess the impact of multinational oil companies' (MOCs') corporate social responsibility (CSR) on rural women's access to modern agricultural inputs in the Niger Delta, Nigeria. A total of 700 rural female farmers were sampled across the region. Results from the use of a logit model indicated that CSR recorded significant success in agricultural development generally, but has undermined equality. This implies that if a woman's agricultural productivity is continuously hindered by unequal access to agricultural resources (or opportunities) and widespread inequality will limit poverty reduction efforts in Nigeria. The results also showed that women depended on CSR of MOCs for policy dialogue and advocacy for women's access to agricultural land and inputs. Supporting agricultural initiatives that focus on empowering women would boost food security in sub‐Saharan Africa.
Lycopsid megaspores from the Upper Triassic of Svalbard and their relationship to the floras and palaeoenvironments of northern Pangaea
Authors: Paterson Niall W. , Morris Peter H. , Mangerud Gunn 
Published: February 2019

AbstractTriassic megaspore assemblages from Svalbard, Arctic Norway, are described for the first time based on the analysis of the Upper Triassic (Carnian–Norian/Rhaetian) Kapp Toscana Group on the island of Hopen. Two megaspore zones are described: the late Carnian ‘Dijkstraisporites beutleriZone’ (undifferentiated De Geerdalen Formation), and the Norian/Rhaetian ‘D. beutleri–Verrutriletes preutilisZone’ (Svenskøya Formation). Megaspores are attributed to heterosporous lycopsids, and probably correspond to the microsporeAratrisporites, which was observed in palynological preparations. Megaspore occurrence was highest in delta‐plain and associated with lake‐mire deposits. However, their close association with marine microfossils suggests episodic marine influence and is consistent with previous interpretations that some Triassic lycopsids occupied marginal marine habitats. The absence of megaspores in the overlying Hopen Member and Flatsalen Formation is probably related to a marine transgression during the early Norian, as indicated by the recovery of low diversity assemblages of agglutinated foraminifera. The transition to ostracod‐dominated microfaunas in the middle part of the formation is consistent with a regionally extensive maximum flooding surface, prior to a return to megaspore‐dominated assemblages in the fluvio‐deltaic deposits of the Svenskøya Formation. Despite the abundance of their mega and microspores, lycopsid fossils are almost entirely absent within palaeobotanical collections from the island, which we ascribe to their herbaceous habit and consequent low preservation potential. The results of this study show lycopsids to be an important component of the local ecosystem and thus contribute to a more complete understanding of the Late Triassic floras of northern‐most Pangaea.