bluuebunny/crossref_metadata_2025_split huggingface dataset:
Number of Dental Stem Cells on Root Canal Dentin after Application of Triple Antibiotic Paste or Calcium Hydroxide: An In Vitro Study
Authors: Gougousis Konstantinos , Giannakoulas Dimitrios G. , Taraslia Vasiliki , Agrafioti Anastasia , Anastasiadou Ema , Kontakiotis Evangelos G. 
Published: September 2019

Abstract
Objective The aim of this study was to evaluate the viability of stem cells from exfoliated and deciduous teeth (SHED) on dentin surface treated with triple antibiotic paste or calcium hydroxide.
Materials and Methods Nine single-rooted extracted premolars were prepared appropriately and divided into three groups. In group A, the root canals were left empty, a triple antibiotic paste was placed in the root canals of group B, and calcium hydroxide was placed in the root canals of group C. After 1 week, the intracanal medicaments were removed, and stem cells were seeded on the treated surface of the specimens for 1 more week. The cells were stained and then observed under confocal microscope over the entire surface of each test material. Counting of the cells was made by Image J (3D) software, as well as manually.
Statistical Analysis To investigate any statistically significant differences between the experimental groups, statistical tests including Kruskal–Wallis and Mann–Whitney U-test were performed. Significance level was set to P < 0.05, and all analyses were performed with SPSS IBM program, v. 21.
Results Groups B and C showed statistically significantly higher number of cells compared to Group A, whereas cells developed in a substrate of calcium hydroxide residues appeared in majority with distinct cores and widened unlike other groups.
Conclusions The effect of calcium hydroxide manifested better results regarding the number of stems cells on root canal surfaces.
Quality of Life Assessment by the Endometriosis Health Profile (EHP-30) Questionnaire Prior to Treatment for Ovarian Endometriosis in Brazilian Women
Authors: Florentino André Vinícius de Assis , Pereira Ana Maria Gomes , Martins João Alfredo , Lopes Reginaldo Guedes Coelho , Arruda Raquel Martins 
Published: September 2019

Objective To evaluate the existence of an association between ultrasound findings and epidemiological and clinical factors using results obtained from the EHP-30 questionnaire in women with ovarian endometriosis.
Methods A cross-sectional observational study was performed between July 2012 and May 2015, in which patients with chronic pelvic pain suggestive of endometrioma, as indicated by the results from a transvaginal pelvic ultrasonography, completed the standardized Endometriosis Health Profile - 30 (EHP-30) questionnaire to access quality-of-life scores before beginning treatment for endometriosis. A total of 65 patients were included. The data was analyzed in the statistical program IBM SPSS Statistics for Windows, Version 22.0 (IBM Corp., Armonk, NY, USA) for the comparison of data through linear multiple regression.
Results The suitability of the linear regression model was confirmed by the histogram of the dependent variable and the residue distribution plot, confirming the trend of linearity as well as the homogeneous dispersion of the residues. The mean age of the patients was 39.7 ± 7.1 years old. The majority was Caucasian (64.5%), had completed higher education (56.5%) and was nulligravida (40.3%). Infertility was present in 48.4% of the patients studied. Out of the total sample, 80.6% of the cases were symptomatic and complained mainly of acyclic pain, 79% of dysmenorrhea, and 61.3% of dyspareunia. This reflects the negative influence of endometriosis on the quality of life of patients with this disease.
Conclusion Dyspareunia and acyclic pain were independent factors of correlation with high scores in the EHP-30 questionnaire, reflecting a worse quality of life.
Two-Year Outcomes of Infants with Stage 2 or Higher Retinopathy of Prematurity: Results from a Large Multicenter Registry
Authors: Tolia Veeral N. , Ahmad Kaashif A. , Jacob Jack , Kelleher Amy S. , McLane Nick , Arnold Robert W. , Clark Reese H. ,   for the MEDNAX ROP Registry Investigators
Published: September 2019

Objective To define the incidence of ophthalmologic morbidities in the first 2 years of life among infants diagnosed with stage 2 or higher retinopathy of prematurity (ROP).
Study Design We prospectively enrolled premature infants with stage 2 or higher ROP. The infants were followed up for 2 years, and we report on data collected from outpatient ophthalmology and primary care visits.
Results We enrolled 323 infants who met inclusion criteria, of which 112 (35%) received treatment with laser surgery (90) or bevacizumab (22). Two-year follow-up was available for 292 (90%) of the cohort. The most common ophthalmologic conditions at follow-up were hyperopia (35%), astigmatism (30%), strabismus (21.9%), myopia (19.2%), anisometropia (12%), and amblyopia (12%). Severe ophthalmologic morbidities such as retinal detachment and cataracts were rare, but occurred in both treated and untreated infants. Overall, 22.6% of the infants were wearing glasses at 2 years, including 8.5% of the untreated infants.
Conclusion Patients with stage 2 or higher ROP remain at significant risk for ophthalmological morbidity through 2 years of age. Infants with regression of subthreshold ROP who do not require treatment represent an underrecognized population at long-term ophthalmological risk.
ClinicalTrials.gov Identifier NCT01559571.
Prevalence of Sexual Dysfunctions and their Associated Factors in Pregnant Women in an Outpatient Prenatal Care Clinic
Authors: Guendler Julianna Azevedo , Katz Leila , Flamini Maria Eduarda Duarte Mello , Lemos Andrea , Amorim Melania Maria 
Published: September 2019

Objective To determine the prevalence of sexual dysfunction and its associated factors in pregnant women.
Methods A descriptive, cross-sectional study including 262 pregnant women aged 18 years or older with gestational age between 10 and 35 weeks. Women with urinary tract infections and conditions of gestational risk were excluded. The Pregnancy Sexual Response Inventory (PSRI) questionnaire was used. We performed a univariate descriptive analysis, and comparisons between the mean values of the sexual function domains were made using the Student t-test. The chi-squared test was used to determine the association between the independent and dependent variables. The prevalence ratios, with their respective 95% confidence intervals, were also estimated, and a multivariate analysis was performed.
Results A total of 64.9% of women reported a decrease in the frequency of sexual activity during pregnancy. Slightly more than half of the women (50.8%) were satisfied, and arousal was reported as excellent/good by 30.5% of them. The frequency of sexual difficulties/dysfunctions increased with pregnancy, rising from 5.7% to 58.8%, and pain during sexual intercourse was reported by 45.8% of them. Having higher education degree decreased the chance of being sexually dissatisfied by 50%. The total PSRI score showed a significant decrease from the prepregnancy period (mean score = 89.8, “excellent”) to the pregnancy period (mean score = 59.2, “good”).
Conclusion The mean sexual function score during pregnancy was classified as good, although most pregnant women reported at least one type of alteration in the sexual function domains, and the report of dissatisfaction was more frequent in women with lower schooling.
Ethanol as Dentin Pretreatment on the Bonding Performance of a Two-Step Etch-and-Rinse Adhesive: An In Vivo Study
Authors: Silva Francisco Cláudio Fernandes Alves , Feitosa Victor Pinheiro , Saboia Vicente de Paulo Aragão 
Published: September 2019

Abstract
Objective The aim of this study was to evaluate the use of 70 vol.% ethanol as a dentin pretreatment on the bond strength (BS) of a two-step etch-and-rinse adhesive.
Materials and Methods Resin composite Class I restorations were clinically bonded to acid-etched dentin of human sound third molars using Adper Single Bond 2 (SB, 3M ESPE) and randomly divided into two major groups: dentin saturated with water (control) or 70 vol.% ethanol (ethanol). The teeth were divided into two subgroups: immediately extracted and tested after 24 hours and extraction after 18 months. Bonded teeth (Adper SB 2) were cut into resin–dentin sticks that were tested by microtensile BS, and the failure mode was thereafter evaluated.
Statistical Analysis Data were statistically analyzed using two-way analysis of variance and Holm–Sidak post hoc test (α = 0.05). Additional bonded resin–dentin slabs from each group were examined under light microscopy (LM) using the Masson's trichrome staining technique.
Results The lowest BS was obtained by ethanol pretreated dentin after aging, while other groups presented similar BS. The LM analysis showed the presence of resin-sparse collagen fibrils in groups examined immediately (24 hours) and the presence of several gaps due to collagen degradation at the interfaces of ethanol pretreated aged specimens (18 months).
Conclusion The use of 70 vol.% ethanol in dentin before the application of a two-step etch-and-rinse adhesive should be avoided once it resulted in a significant drop on the BS.
Quantification of textual comprehension difficulty with an information theory-based algorithm
Authors: Ribeiro Louise Bogéa , Rodrigues Anderson Raiol , Costa Kauê Machado , da Silva Filho Manoel 
Published: September 2019

AbstractTextual comprehension is often not adequately acquired despite intense didactic efforts. Textual comprehension quality is mostly evaluated using subjective criteria. Starting from the assumption that word usage statistics may be used to infer the probability of successful semantic representations, we hypothesized that textual comprehension depended on words with high occurrence probability (high degree of familiarity), which is typically inversely proportional to their information entropy. We tested this hypothesis by quantifying word occurrences in a bank of words from Portuguese language academic theses and using information theory tools to infer degrees of textual familiarity. We found that the lower and upper bounds of the database were delimited by low-entropy words with the highest probabilities of causing incomprehension (i.e., nouns and adjectives) or facilitating semantic decoding (i.e., prepositions and conjunctions). We developed an openly available software suite called CalcuLetra for implementing these algorithms and tested it on publicly available denotative text samples (e.g., articles, essays, and abstracts). We propose that the quantitative model presented here may apply to other languages and could be a tool for supporting automated textual comprehension evaluations, and potentially assisting the development of teaching materials or the diagnosis of learning disorders.
Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood
Authors: Rasheed Mohammed Ata Ur , Hickman Carole J. , McGrew Marcia , Sowers Sun Bae , Mercader Sara , Hopkins Amy , Grimes Vickie , Yu Tianwei , Wrammert Jens , Mulligan Mark J. , Bellini William J. , Rota Paul A. , Orenstein Walter A. , Ahmed Rafi , Edupuganti Srilatha 
Published: September 2019

SignificanceThe live-attenuated mumps-measles-rubella (MMR) vaccine has been highly successful in the United States since its introduction 47 years ago. However, for the past decade, mumps outbreaks have been occurring among young adults who were vaccinated as children. Waning immunity has been proposed as a key contributing factor to mumps resurgence. In our sample (n= 71) of 18- to 23-year-old college students, the majority had detectable mumps IgG antibodies by enzyme-linked immunosorbent assay (ELISA) but the magnitude was lower than rubella. Neutralizing antibody titers were 6-fold lower to a circulating genotype G mumps strain versus the vaccine strain. Ten percent of our participants had no detectable memory B cells to mumps. Strategies are needed to improve immunity to the mumps vaccine.
CCA1 and LHY contribute to nonhost resistance to Pyricularia oryzae (syn. Magnaporthe oryzae) in Arabidopsis thaliana
Authors: Yamaura Saaya , Yamauchi Yuri , Makihara Motoi , Yamashino Takafumi , Ishikawa Atsushi 
Published: September 2019

ABSTRACT
The circadian clock enables plants to adapt to their environment and control numerous physiological processes, including plant–pathogen interactions. However, it is unknown if the circadian clock controls nonhost resistance (NHR) in plants. To find out, we analyzed microarray data with the web-based tool DIURNAL to reveal that NHR-related genes show rhythmic expression patterns in the absence of a pathogen challenge. Our clock mutant analyses found that cca1-1 lhy-11 double mutant showed compromised NHR to Pyricularia oryzae, suggesting that two components of the circadian clock, CCA1 and LHY, are involved in regulating penetration resistance in Arabidopsis thaliana. By analyzing pen2 double mutants, we revealed that CCA1 contributes to time-of-day-dependent penetration resistance as a positive regulator and that LHY regulates post-penetration resistance as a positive regulator. Taken together, our results suggest that the circadian clock regulates the time-of-day-dependent NHR to P. oryzae and thus enables A. thaliana to counteract pathogen attacks.
Abbreviations: EE: evening element; ETI: effector-triggered immunity; NHR: nonhost resistance; PAMP: pathogen-associated molecular pattern; PTI: PAMP-triggered immunity; SAR: systemic acquired resistance.
The very large electrode array for retinal stimulation (VLARS)—A concept study
Authors: Lohmann Tibor Karl , Haiss Florent , Schaffrath Kim , Schnitzler Anne-Christine , Waschkowski Florian , Barz Claudia , van der Meer Anna-Marina , Werner Claudia , Johnen Sandra , Laube Thomas , Bornfeld Norbert , Mazinani Babak Ebrahim , Rößler Gernot , Mokwa Wilfried , Walter Peter 
Published: September 2019

Abstract

Objective. The restoration of vision in blind patients suffering from degenerative retinal diseases like retinitis pigmentosa may be obtained by local electrical stimulation with retinal implants. In this study, a very large electrode array for retinal stimulation (VLARS) was introduced and tested regarding its safety in implantation and biocompatibility. Further, the array’s stimulation capabilities were tested in an acute setting. Approach. The polyimide-based implants have a diameter of 12 mm, cover approximately 110 mm2 of the retinal surface and carrying 250 iridium oxide coated gold electrodes. The implantation surgery was established in cadaveric porcine eyes. To analyze biocompatibility, ten rabbits were implanted with the VLARS device, and observed for 12 weeks using slit lamp examination, fundus photography, optical coherence tomography (OCT) as well as ultrasound imaging. After enucleation, histological examinations were performed. In acute stimulation experiments, electrodes recorded cortical field potentials upon retinal stimulation in the visual cortex in rabbits. Main results. Implantation studies in rabbits showed that the implantation surgery is safe but difficult. Retinal detachment induced by retinal tears was observed in five animals in varying severity. In five cases, corneal edema reduced the quality of the follow-up examinations. Findings in OCT-imaging and funduscopy suggested that peripheral fixation was insufficient in various animals. Results of the acute stimulation demonstrated the array’s ability to elicit cortical responses. Significance. Overall, it was possible to implant very large epiretinal arrays. On retinal stimulation with the VLARS responses in the visual cortex were recorded. The VLARS device offers the opportunity to restore a much larger field of visual perception when compared to current available retinal implants.
Shape effects on the diamagnetic susceptibility in Inhomogeneous Quantum Dots
Authors: M’zerd S. , Janati. Edrissi S. , Chrafih Y. , Rahmani K. , Khenfouch M. , Zorkani I. , Jorio A. 
Published: September 2019

Abstract
We have studied the magnetic field effects on the diamagnetic susceptibility and binding energy of a hydrogenic impurity in a Inhomogeneous Quantum Dots by taking into account various geometries of these systems like spherical, cylindrical and cubic inhomogeneous Quantum Dots. The calculation was performed with the use of a variational method in the effective mass approximation. We describe the effect of the quantum confinement by an infinite deep potential. In order to make a comparison of the geometry, the results obtained for these tree structures show that the diamagnetic susceptibility and the binding energy is proportional with the magnetic field and strongly depend on the position of the donor. There is more pronounced for the large spherical layer.
ELABORATION AND CHARACTERIZATION OF ZNO THIN FILMS STRUCTURAL AND OPTICAL STUDY
Authors: Adar M , Najih Y , Charafih Y , Rahmani K , Khaouch Z , Mabrouki M 
Published: September 2019

Abstract
The Nano-topographical structure of the solid surface is known as a necessary parameter in the physicochemical characterization and wetting properties. In this study, the physicochemical properties are evaluated by calculating the surface energy and by measuring the contact angle. The structural proprieties were determined using XDR. The optical proprieties were studied using the UV-visible technics. Substrates used in this study are the zinc oxide thin films deposited on the glass by sputtering under different powers (150, 200 and 250 watt). The Nano -topographic properties were examined using the atomic force microscopy (AFM) in order to calculate the roughness of different substrates. As results, the images obtained by atomic force microscopy showed that the growth of the power causes the growth of the roughness. XRD diagram assessment revealed that the deposited films have a preferential crystallographic direction according to the (002) plane while maintaining the initial orientation. The optical characterization showed that the bandwidth of these films is in the order of 3.28 eV. It is interesting to mention that the increase in RF power has slightly increased the energy of gap.
Synthesis, characterization and evaluation of bioactivity of glasses in the CaO-SiO2-P2O5-MgO system with different CaO/MgO ratios
Authors: Chajri S , Bouhazma S , Adouar I , Herradi S , Khaldi M , El Bali B , Lachkar M 
Published: September 2019

AbstractBioactive glasses (80Mg, 70Mg, 60Mg and 50Mg) in the system SiO2-CaO-P2O5-MgO were prepared by sol-gel method and then characterized. The structure of the synthesized samples has been studied by X-ray diffraction (XRD), Fourrier Transform Infrared Spectroscopy (FTIR) and Environmental Scanning Electron Microscopy (ESEM).In vitrobioactivity tests were performed in Simulated Body Fluid (SBF). The apparent density and wettability variation with time were measured. Thein vitrostudies showed the formation of an apatite-like layer covering areas of the material surface. The variation in the CaO/MgO ratio has an influence on the chemical durability and bioactivity. The XRD and FTIR analysis revealed that the samples with larger CaO/MgO ratio exhibited better bioactivity. The results showed that the 50Mg glass which has the higher content of CaO/MgO is hydrophilic sample for the two used fluids (water and SBF). The porosity and hydrophilicity increase with increased the rate of CaO/MgO. The surface of bioglasses became rougher with the increased CaO/MgO ratio, which may lead to a decrease in water contact angle.
Nanostructured Tungsten Trioxide (WO3): synthesis, structural and morphological investigations
Authors: Hatel R , Baitoul M 
Published: September 2019

Abstract
Tungsten trioxide (WO3) has attracted considerable attention due to its promising and remarkable properties. In this study, we have prepared WO3 nanostructures via a simple chemical method using tungsten carbide (WC) as a precursor. This novel approach has many advantages such as high yields, simple methodology and easy work up. The X-ray diffraction (XRD) pattern initially revealed the formation of the intermediate phase of tungsten trioxide hydrate (WO3.H2O), then the complete transformation to pure WO3 after annealing at 600°C for 5h in air atmosphere. The prepared WO3 nanostructures crystallized into a monoclinic phase. The Scanning electron microscopy (SEM) image indicates the exceptional porous morphology, which consisted of hollow sphere-like shape with a uniform distribution. Fourier transform infrared (FTIR) spectroscopy confirmed the structural composition and the purity of the formed WO3. The experimental results proved that our simple approach offers a promising route to prepare WO3 nanostructures as high performance material for advanced applications.
Study on the effect of Er dopant on the structural properties of ZnO nanorods synthesized via hydrothermal method
Authors: Achehboune M , Khenfouch M , Boukhoubza I , Mothudi B , Zorkani I , Jorio A 
Published: September 2019

Abstract
Rare earth Er-doped ZnO nanorods were prepared by a simple hydrothermal method in order to search for a new functional for potential application in optoelectronic. Nanorods were deposited onto glass substrates with zinc nitrate, hexamethylenetetramine and Erbium chloride as starting materials. The results obtained by XRD spectrum indicated the presence of hexagonal (wurtzite) structure for both pure and Er doped ZnO NRs with additional cubic phase of Er2O3 that appeared in the doped sample. The size and lattice strain of particles have increased after doping with Erbium. The increase of their sizes can be explained by the incorporation of Er atoms into ZnO lattice.
The Research on the Simulation of VHF Radio Broadcasting Loss
Authors: Li Ting , Zhang Han , Gao Xiufeng , Wang Shuai 
Published: September 2019

Abstract
VHF radio is a crucial part of the communication system in the battlefield. Since that the paper has adopted the idea of hierarchical modelling, and aiming at building up a simulation model of VHF radio accordingly, which is described with CCIR model, and the elevation data is presented with topographical map. Finally, the battlefield simulation of VHF radio is implemented with OMNET++. The result of simulation validated the credibility of the method, which would provide the simulation of battlefield in complicated electro-magnetic environment with new practical approaches.
SINR and MI-based Robust Transmitted Waveform Design in the Situation of Multiple Targets
Authors: Chen Xu , Wang Bin , Wu Rihan , Fan Ruiyi , Wang Lulu 
Published: September 2019

Abstract
Most of the previous researches on transmitted waveform design assume that the radar can perceive the real target spectrum, as the environments of the radar target become more and more complex, the real target spectrum cannot be accurately captured by radar in many cases and the required performances of detection and estimation for radar cannot be met. Therefore, under the complex electromagnetic environment and the scenario of multiple targets, to ensure the detection and estimation performance of radar system, the SINR and MI-based robust transmitted waveform design methods are proposed in this paper. Simulation results indicate that the designed robust transmitted waveforms ensure the detection and parameter estimation performance effectively and provide useful guidance for energy allocation of transmitted waveform.
Estimation of Intrinsic Dimension using Supervised Parameter Selection Method
Authors: Qiu Haiquan , Yang Shulun 
Published: September 2019

Abstract
In this paper, we propose a new method for estimating the intrinsic dimension of datasets. The new method uses the local information of different scales of the sample points (by adjacency matrix) to estimate the intrinsic dimension. The only parameter used in the new method is the scaling ratio k, which determines the adjacency matrix of different scales. We propose a parameter selection method based on the difference of estimated dimension and the classification accuracy of projection data. Experiments on real datasets demonstrate the effectiveness of the proposed method.