bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vitamin B12 partially rescues embryonic cell migration defects inC. elegansephrin mutants by improving both propionic acid breakdown and one-carbon cycle metabolic pathways
Authors: Ganjawala Tushar H. , Hsiao Erin , Amom Prativa , Molaei Radmehr , Goodwin Samantha , Zacharias Amanda L. 
Published: November 2024

ABSTRACTSuccessful cell migration followed by tissue fusion is required for organogenesis in a number of tissues, many of which are susceptible to gene-environment interactions that can result in congenital anomalies. InC. elegansembryogenesis, one such event is the closure of the ventral cleft, which must occur as the first step in morphogenesis, otherwise embryos arrest; this process depends on ephrin signaling, but no single gene mutation is fully penetrant embryonic lethal. We exposed hermaphrodites mutant forvab-1, theC. elegansephrin receptor, to various environmental conditions and found that vitamin B12 supplementation could partially rescue the embryonic lethality of multiple alleles from 40% survival to 63% survival. Analysis ofvab-1mutant phenotypes showed that vitamin B12 reduced the frequency of ventral cleft closure failure by promoting more normal cell positions and increased migration by the precursor cells of those that adhere to close the cleft. We found that vitamin B12 partially rescued the embryonic lethality of other ephrin pathway mutants, but not mutants that have ventral cleft defects due to cell adhesion or cell fate defects. We found that rescue by vitamin B12 depends on its functions in both mitochondrial propionic acid breakdown and the one-carbon cycle, and that antioxidant treatment can also partially rescue ephrin pathway mutants. These results are distinct from the larval response to vitamin B12, which depends only on the one-carbon cycle, emphasizing the unique metabolism of embryos and particularly the metabolic needs of migrating cells. Overall, our findings highlight theC. elegansembryo as a model system to investigate gene-environment interactions and developmental metabolism.
Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase
Authors: Orofiamma Laura A , Delos Santos Ralph Christian , Mehrabi Ayshin , Leshchyshyn Nikol , Hesketh Geoffrey G , Rahmani Sadia , Patel Aesha , Fekri Farnaz , Ata Rehman , Ratcliffe Colin DH , Crupi Mathieu JF , Mulligan Lois , Park Morag , Gingras Anne-Claude , Antonescu Costin N 
Published: November 2024

SummaryThe cell surface abundance of many proteins is controlled by clathrin-mediated endocytosis (CME). CME is driven by the assembly of clathrin and other proteins on the inner leaflet of the plasma membrane into clathrin-coated pits (CCPs). Regulation of CCP dynamics allows for control of the function of specific cell surface proteins, impacting a range of cellular outcomes. AMP-activated protein kinase (AMPK) becomes activated upon metabolic insufficiency and facilitates cellular adaptation to nutrient stress. Here, we examined how AMPK regulates CME and the cell surface membrane traffic of β1-integrin. We find that AMPK controls CCP dynamics and regulates the abundance of the endocytic adaptor protein Dab2 within CCPs in a manner that requires the GTPase Arf6, thus selectively promoting the CCP recruitment and internalization of β1-integrin. This reveals a novel signaling pathway for cargo-selective metabolic regulation of CME by AMPK, impacting the function of cell surface proteins such as integrins.
Financial mechanisms for energy transitions: a review article
Authors: Long Pham Dinh , Tram Nguyen Huynh Mai , Ngoc Pham Thi Bich 
Published: November 2024

PurposeThe transition from fossil fuel-based energy systems to renewable energy sources, commonly referred to as the energy transition, is essential for combating climate change. However, comprehensive studies that thoroughly examine the financial mechanisms involved in this process are lacking. Despite the availability of various financial tools, there is a notable absence of extensive research that synthesizes and categorizes these mechanisms into broad groups.Design/methodology/approachA systematic literature review is used to explore a comprehensive framework for financial mechanisms related to the energy transition and their application across six stages of the process.FindingsThe framework of financial mechanisms for energy transition encompasses these six factors: public financing mechanisms, private financing mechanisms, market-based mechanisms, innovative financing mechanisms, risk mitigation instruments and institutional support and capacity building.Originality/valueThis is the first study that thoroughly reviewed the financial mechanisms involved in the energy transition process.
Strategic human capital analytics and new venture performance: role of dual nationality founding member
Authors: Faiz Misbah , Sarwar Naukhez , Tariq Adeel , Dias Jordão Ricardo Vinícius , Memon Mumtaz Ali 
Published: November 2024

PurposeStrategic human capital analytics (SHCA) has proven to be promising for improved organizational performance; however, research remains unclear about its influence on new venture performance. Building on the dynamic capabilities view (DCV), this study investigates the relationship between SHCA and new venture performance via generative capabilities with the moderating role of dual nationality founding members.Design/methodology/approachA quantitative research study has been carried out. Data was collected via a survey form from 313 founding members of new tech ventures and analyzed using Hayes process macro model.FindingsResearch results show that the generative capability mediates the linkages between SHCA and new venture performance. Whereas, the dual nationality of a founding member strengthens the linkages between SHCA and generative capability due to their diverse perspective, larger networks, cognitive flexibility, and resilience, which are important for generative capabilities and SHCA.Originality/valueThe originality of these results lies in the exploration of the linkages between dual nationality and generative capability, as well as the special elements, such as diverse perspectives, larger networks, cognitive flexibility, and resilience, which are highlighted as possible advantages of dual nationality in the context of SHCA and new venture performance.
With Latour in our hands: discovering the politics of organizing and the aesthetic matter of things
Authors: Raviola Elena , Gasparin Marta 
Published: November 2024

PurposeThe purpose of this paper is to pay tribute to the work of Bruno Latour and its relevance for organization scholars particularly, by relentlessly going beyond the reified category of “organization.” We rely in particular on our own experiences of conducting fieldwork with Latour in our hands and expose our journeys, sometimes feeling naked, embarrassed and naive. By following traces of actions, paying attention to things and appreciating plurality, with Latour we have discovered the politics of organizing and the aesthetic matter of things.Design/methodology/approachWe use our own methodological experience to describe how Latour’s work has helped us concretely. We structure our methodological reasoning around three excursions in the field, corresponding to our different fieldwork journeys. For each excursion, we rely on descriptions and reflect on how we have traced actions, paid attention to things and appreciated plurality, as set out in the introduction.FindingsWe render through excursions our Latour moments, that is, critical moments in fieldwork, where we get stuck and embarrassed and where Latour’s texts with simple questions help us move. Against the critique of ANT as being apolitical and unable to account for the body, we explain how we have precisely, through our ANT investigations, intersected between politics, aesthetics and organizing through three main ways of displacing us in the field: leaving a priori categories and questioning what we see; placing our view somewhere and moving it in an oligopticon-like way; and “thick thinging.”Originality/valueThe paper is a tribute to Latour’s work and wants to contribute to emphasizing his relevance for understanding not only organization in general but also the politics and aesthetics of organizing. We reassemble our fieldwork journeys and, despite their being personal to us, we believe that our learnings are recognizable and recognized by other scholars. We conclude with a research suggestion relevant to organization scholars.
Nordic legal overseers and institutional openness in crises: Challenges and adaptation during the COVID‐19 pandemic
Authors: Erkkilä Tero , Mölsä Juho , Vähäniitty Ella 
Published: November 2024

AbstractWe analyze challenges and adaptation strategies of Nordic legal overseers, the Parliamentary Ombudsmen and Chancellors of Justice in Denmark, Finland, Norway and Sweden, amid the COVID‐19 crisis. We study how the accountability capacities of the legal overseers were affected when standard practices of inclusive decision‐making were severed, and how they adapted to these challenges. Furthermore, we seek to understand what explains observed variation in the degree of challenges and needed adaptation measures. The observed challenges include increased and sometimes politicized caseload, limited expertise in medical field and conflicting or underdefined mandates among the institutions. The challenges and adaptation were conditioned by institutional traditions and ad‐hoc arrangements in crisis management. In Finland and Sweden, the legal overseers became prominent sites for legal and public accountabilities of crisis governance and experienced more acute organizational challenges from increased and politicized caseloads as actors were seeking alternative accountability forums when participation and openness were severed. In Norway and Denmark, where other institutions were prominent in overseeing crisis governance and its legality, the legal overseers had a more pressing need to adapt for an evolving organizational landscape with new ad‐hoc arrangements to oversee crisis management. Contributing to institutional approach on accountability and ombudsman research, we find a dynamic relationship between the government openness and legal oversight where the constraints for openness in crisis governance led to various challenges for the legal overseers' accountability capacities but to which they adapted by promoting openness as a right as well as an enabling mechanism for other accountability institutions.
Border fortification and legibility: Evidence from Afghanistan
Authors: Blair Christopher W. 
Published: November 2024

AbstractStates often fortify their borders against militant threats. How do these efforts shape civilian welfare and perceptions in borderland communities? I conceptualize border fortification as a legibility‐building endeavor. By bolstering state reach in areas of weak historical penetration, fortification enhances the government's capacity for monitoring, administration, and control. Yet, expanding state authority also disrupts traditional cross‐border markets. A trade‐off between security and corruption emerges in consequence. I provide evidence for this theory in a difference‐in‐differences framework, combining administrative records on violence and representative data from a NATO‐commissioned survey fielded across Afghanistan. Fortification facilitates government information‐collection, improving security provision and fostering civilian reliance on state forces. Enhanced state capacity is countervailed by negative economic impacts. By disturbing the informal borderland economy, fortification fuels criminalization and local opposition. Civilians rely on illicit economic entrepreneurs to sustain traditional market access. Higher smuggling rents fuel official corruption and bribe‐taking. The findings point to a key dilemma inherent in border fortification strategies.
The indispensable function of agricultural cooperatives in South Sudan
Authors: Francesconi Nicola , Miteng Justin , Wouterse Fleur 
Published: November 2024

AbstractMost of South Sudan's rural population ekes out a living from farming in a fragile context characterized by compounding and interrelated shocks. The productivity of maize, a key staple, has remained comparatively low. South Sudan is currently transforming its agricultural sector to be at the centre of its economic activity. Programming has zoomed in on seed‐related interventions. Cooperatives, which are longstanding and widespread in the country, are leveraged to distribute seed and, by mitigating production risk, could contribute to resilient development. To shed light on the key functions of cooperatives and how their role can be enhanced, we analysed recent data from 1247 maize‐producing households and 126 agricultural cooperatives from South Sudan. We find that through their services cooperatives contribute to both increasing maize yields and reducing their variability. Yield increases associated with seed production and/or distribution services are substantial but exclusive to members. Managerial capital in the form of a hired manager instead also generates spillover effects to the broader community. Our findings point to the relevance of cooperatives as indispensable stakeholders for the resilient development of the country and the need for investments to strengthen their managerial capital and enhance the provision of services related to seed production and/or distribution.
Faience beads excavated from Laolongtou cemetery, Yanyuan: new evidence of the cultural exchange between the south‐western and north‐western parts of China
Authors: Liu Yunling , Tian Jianbo , Zhou Zhiqing , Hao Xiaoxiao , Li Haichao 
Published: November 2024

AbstractAncient Chinese beads provide important evidence of cultural exchanges. This study used a scanning electron microscope with an energy‐dispersive spectrometer to analyse the microstructure and chemical composition of faience beads excavated from Laolongtou cemetery in Yanyuan county, China. Based on the analysis results, two glazing methods (efflorescence and cementation) and two bead types (high‐Pb and high‐K beads) were identified. A comparison of the chemical compositions of samples unearthed at the Laolongtou cemetery and samples from north‐western China indicated close regional contact. Bronze wares and burial customs in Laolongtou cemetery also revealed that the Yanyuan region might be a significant node in the Southern Silk Road between the south‐western and north‐western parts of China and even in Southeast Asia.
Effects of manakin gut passage on germination of a neotropical melastome shrub (Melastomataceae)
Authors: Rompf Katherine , Anderson H. Luke , Karubian Jordan 
Published: November 2024

AbstractGut passage is an important but understudied component of animal‐mediated seed dispersal that can impact germination and survival. Melastomataceae plants are abundant and ecologically important throughout the tropics, but studies have obtained contrasting results regarding effects of avian gut passage on melastome germination. We conducted a paired germination experiment to test how gut passage by four species of manakins—key avian dispersers of melastomes—affects germination of the pioneer melastome shrub Miconia rubescens. Manakin gut passage accelerated M. rubescens germination, with gut‐passed seeds germinating an average of 5.1 days earlier than controls, and percent germination of gut‐passed seeds was significantly higher at 20 and 40 days post‐planting. Interestingly, manakin species varied in their gut passage effects, with L. velutina having stronger overall germination effects than M. manacus. Within species, greater body mass was correlated with higher percent germination and shorter times to first germination. Within M. manacus, seeds passed by females had significantly shorter times to first germination than seeds passed by males. Because control seeds were manually depulped in the experiment, the observed gut passage effects are likely attributable to minor scarification of the seed coat during gut transit. Our results suggest manakin gut passage can have biologically meaningful impacts on melastome germination, and the magnitude of these effects can vary based on manakin species, mass, and sex. This study refines our understanding of the “quality” component of seed disperser effectiveness in an iconic dispersal mutualism, with implications for plant community composition and recovery of deforested neotropical ecosystems.Abstract in Spanish is available with online material.
Nothing to hide: How governments justify the adoption of ag‐gag laws
Authors: Weiler Anelyse M. , Zavitz Tayler 
Published: November 2024

AbstractMainstream practices for producing meat, eggs, and dairy raise numerous concerns regarding public health, animal welfare, and environmental integrity. However, governments worldwide have expanded anti‐whistleblower legislation that constrains informed public debate. Since 2019, several Canadian provinces have adopted so‐called “ag‐gag” laws designed to prevent hidden‐camera investigations on farms and meat processing facilities. How do governments across Canada justify ag‐gag laws as serving the public interest? To what extent do agricultural industry interests shape government adoption of ag‐gag laws? Using Freedom of Information requests and debate records from provincial legislatures, we find that biosecurity is the most prominent justification for ag‐gag laws, and that governments exhibit a close, collaborative relationship with industry actors. This case demonstrates that when it comes to contested sites of capital accumulation, governments are drawing on new spatial‐legal tools to protect the status quo interests of private industry by dissuading dissent, debate, and public scrutiny.
The fertility gap and economic freedom
Authors: Piano Clara E. , Stone Lyman R. 
Published: November 2024

AbstractThe difference between desired fertility and achieved fertility is called the fertility gap. This paper investigates the relationship between economic freedom and the fertility gap across the United States since greater economic freedom may empower individuals to choose work more compatible with their family goals. We test this hypothesis using individual measures of fertility preferences from a nationally representative survey of reproductive‐aged women (2020–2024) and find evidence that women are more likely to achieve their family goals in states with greater economic freedom. This effect is strongest when focusing on variation in labor market freedom.
Specialization trends in economics research: A large‐scale study using natural language processing and citation analysis
Authors: Galiani Sebastian , Gálvez Ramiro H. , Nachman Ian 
Published: November 2024

AbstractThis article conducts a comprehensive analysis of specialization trends within and across fields of economics research. We collect data on 24,273 articles published between 1970 and 2016 in general research economics outlets and employ machine learning techniques to enrich the collected data. Results indicate that theory and econometric methods papers are becoming increasingly specialized, with a narrowing scope and steady or declining citations from outside economics and from other fields of economics research. Conversely, applied papers are covering a broader range of topics, receiving more extramural citations from fields like medicine, and psychology. Trends in applied theory articles are unclear.
Calculative Practices Shaping the Global Accountability Forum for Climate Agenda
Authors: Soares Thiago Vitor Ferreira , Aquino André Carlos Busanelli de 
Published: November 2024

ABSTRACTCalculative practices are everywhere, including the enactment and diffusion of sustainable development goals, such as quantifying and monetizing carbon markets, criteria for allocating donations for sustainability programs, and performance measurement of compromises and goals. We critically explore the performativity and counter‐performativity from the calculative practices orbiting and shaping the annual debate on climate governance and how they are related to the vulnerability of populations. Our qualitative analysis comprised a comprehensive set of documents produced by enrolled participants of meetings and workshops between two annual Conferences of the Parties of the United Nations. We identified and exemplified three calculative practices, and despite their intended performativity, some counter‐effects, like social exclusion and criticism by stakeholders, arise.
Sustainability and Performance Evaluation in Third Sector Partnerships: The Case of Turin Fast Track City
Authors: Amelio Stefano , Gazzola Patrizia , Biancone Paolo , Brescia Valerio 
Published: November 2024

ABSTRACTCOVID‐19 radically changed how public services (activities of general interest) are pursued and administered. The search for resilient models has prompted public administration to test new regulatory approaches and to involve the third sector in the provision of primary services. This study investigates the sustainability and capacity of these models, specifically the implementation of a co‐planning and co‐design model aimed at measuring the possible creation of value and achieving common objectives. On the basis of an analysis of the development of the Turin Fast Track City project, the study employs a longitudinal method to identify not only the sustainability of the model but also new effective performance measurement tools, such as SIA analysis and integrated social accounting using financial and non‐financial elements. The study also highlights critical elements aimed at supporting future investigations.
The life cycle of intermittent streams: How do fish communities respond to annual cycles of wetting and drying?
Authors: Kelly Benjamin T. , Bruckerhoff Lindsey A. 
Published: November 2024

Abstract

Intermittent streams periodically cease to flow but still support diverse aquatic assemblages. Community dynamics within intermittent streams are likely driven by a wide range of factors, including drying regime, refuge availability, and connectivity with perennial systems.

We compared fish community dynamics over the course of a drying and rewetting period to quantify differences in fish community composition and recovery trajectories across a gradient of drying. We predicted that shifts in fish community structure as streams dry and rewet would be similar across streams with similar drying regimes and streams with more severe drying would be less likely to recover when streams rewetted.

Seasonal shifts in community composition were variable in streams that retained isolated pools, with similar patterns occurring in streams of similar size.

Despite a lack of synchrony in shifts in community composition among sites, fish communities exhibited recovery post‐drying across all drying regimes.

The quick recovery of stream fish communities after drying may suggest intermittent streams provide beneficial habitats or resources and highlight the importance of network connectivity to allow community recovery after drying.
Meter Against Essentialism
Authors: Eldridge Hannah Vandegrift 
Published: November 2024

AbstractRecent scholarship on poetic materiality has found itself caught between celebration of the way rhythm might link language and the body, on the one hand, and critiques of the way such a link can lead and has led to various types of essentialism, on the other. Rhythm has a long history of activating essentialist tropes of primitivism and savagery, which in turn see certain groups (children, women, the “insane,” or racialized others) as fully determined by sensory language and bodily rhythm. In the face of this history and its afterlives, I argue for meter as a resource to help readers and scholars of poetry identify and critique essentializing approaches while upholding at least the possibility of claims for the affective and somatic efficacy of poetic language.