bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determination of electrical parameters for the electrochemical treatment of soils contaminated with oil
Authors: Meshalkin V P , Shulaev N S , Chelnokov V V , Pryanichnikova V V , Kadyrov R R 
Published: June 2019

Abstract
The electrochemical method of soil cleaning by passing small amperage has rather high efficiency for oil products, phenols, salts, heavy metals, and other chemicals pollution. Cleaning can be realized through a whole complex of physical, chemical and biological processes. The most important are the electrokinetic movement of the pollutant, the oxidation and evaporation of the components. The arrangement of anodes and cathodes that reduces the resistance between the electrodes by creating in the interelectrode space an electric field close to homogeneous is considered. This calculation allows to determine the number of electrodes, the amperage between them, the voltage depending on the properties of the soil, the area, the depth of contamination of the treated area, the geometric parameters of the electrodes and the required degree of cleaning.
About the assessment of the chrisothal asbestos dust slip into the atmosphere as a random function
Authors: Burkhanova R A , Ostaali M , Nikolenko M A , Lupinogin V V , Azarov V N 
Published: June 2019

Abstract
The paper presents the study of the fractional efficiency of asbestos-cement dust slip from the aspiration system as a random function. Total slip was considered as a random variable. Also dispersed analysis of dust from the aspiration systems serving the process equipment and processes was performed. Examples of the function of the dust passage in the production of asbestos-cement products before cleaning in the CSF apparatus and after cleaning showed that the total dust slip in CSF apparatuses as a random value corresponds to the normal distribution law. The density characteristics and the distribution function for the total asbestos cement dust slip penetration are determined. The range of variation of the random dust slip function for CSF-150 and CSF-300 apparatuses is presented. Recommendations are given to reduce the negative impact of the dust factor in the air of enterprise working areas.
Construction-technical inspection of cemetery church of St. Peter and Paul in Želiv
Authors: Daňková J , Mec P , Majstríková T , Škopcová M 
Published: June 2019

Abstract
This article deals with the construction-technical inspection of Cemetery Church of St. Peter and Paul in Želiv. The church is a cultural heritage and its history dates back almost for 900 years. The construction-technical inspection was performed with the goals to survey construction structures and define their major defects and failures before the commencement of constructional renovation. The survey also included measuring humidity of masonry and wooden parts of the structure.
Crystallization process in the preparation of the tetracalcium ferroaluminate
Authors: Ravaszová S , Dvořák K 
Published: June 2019

Abstract
The study of the origin, stability and properties of various calcium silicate polymorphs is important for a better understanding of the processes involved in the production of Portland clinker. At the same time, the synthetic pure clinker phases can serve in further investigations, such as hydration or the effects of plasticisers. The aim of this article is to prepare the pure phase of tetracalcium ferroaluminate and to observe the crystallization process based on the calculation of the size of the crystallite using the simplest method, the Scherrer’s equation. Based on the results of the X-Ray analysis, the temperature of 1350 °C with a soaking time of 3 hours is sufficient to produce the tetracalcium ferroaluminate pure phase. This firing mode is also characterized by a very good development of the crystalline structure.
Electronic waste as a filler in concrete
Authors: Junak J , Junakova N , Csiszar V 
Published: June 2019

Abstract
Electrical appliances are becoming an everyday part of our lives. The more we use them, the more we contribute to the emergence of new waste - electronic waste (WEEE). E-waste is a significant source of plastics, metals and others. Electronic waste (cables) as a volume substitute for natural aggregates (5, 10 and 20%) in our experimental work was used. Flexural and compression was observed on prepared samples, beams 100x100x400 mm. The use of electrical waste as a filler has resulted in a slight reduction in the resulting strengths (about 10%), but the properties of the concrete with dispersed reinforcement have been founded. Flexural strengths ranged from 3.5 to 5.1 MPa and compressive strengths were in the range of 15.2 to 28.2 MPa after 28/60 days of curing.
Alternative reuse of bottom sediments in construction materials: overview
Authors: Junakova N , Junak J 
Published: June 2019

Abstract
In this paper, the paths of management of the dredged bottom sediments are discussed. Focus is made on the possibility of a recycling method, which consists of the reuse of sediments as a raw material in constructions. The results of selected studies concentrated on the sustainable sediment reuse as a raw material to manufacture lightweight aggregates, bricks and concrete are summarized.
Influence of type and composition of aggregate on mechanical parameters of concrete
Authors: Tazky M , Osuska L , Bodnarova L 
Published: June 2019

Abstract
The paper deals with a thorough analysis of the influence of the type of aggregate and its resulting grain size curve on the basic strength parameters of concrete. From the point of view of the type, natural crushed aggregate of amphibolitic type, natural crushed aggregate of granodioritic type and natural mined sedimentary aggregate of the psammitic type were monitored. The same concrete strength class was proposed for the analysis of the impact of individual types of aggregates. In one case it was a concrete mixture with a maximum aggregate grain size Dmax 16 mm with a continuous grain size curve and in the second case a concrete mixture with a maximum grain size Dmax of 22 mm with a discontinuous grain size curve, in the absence of a 4-8 mm fiction. In both cases, the mixture of individual aggregate fractions was determined so that the resulting grain size curve of the mixture was the same for all aggregate types. Thanks to this approach it was possible to directly monitor the influence of the type of aggregate and the grain size curves on the resulting concrete parameters. The results of the experiment show that a significant impact while maintaining the same grain size curves of the resulting aggregate mixture can be seen mainly in the type of aggregate. The absence of a 4-8 mm fraction when designing a concrete mixture with a Dmax of 22 mm proves to be completely problem-free from the point of view of concrete parameters in both fresh and hardened condition. A part of the research was also verification of the possibility of using natural crushed sand of fraction 0-4 mm for production of high-strength situ ready-mixed concretes.
Evaluation of the South Korean national long-term care insurance-funded cognitive function training programme for older people with mild dementia
Authors: Ju Yeong Jun , Nam Chung Mo , Lee Sang Gyu , Park Sohee , Hahm Myung-Il , Park Eun-Cheol 
Published: June 2019

Abstract

Objectives
despite the extensive literature on the effectiveness of cognitive training, its effectiveness has not been demonstrated within a population-based long-term care system. To provide cognitive training services to older people with mild dementia, Korea introduced a special dementia rating, as a long-term care grades, in the national long-term care insurance in July 2014. These services are only offered to those with the special dementia rating. This study evaluated the national long-term care insurance-funded cognitive function training programme for older people with mild dementia.

Methods
data were derived from the Korean National Health Insurance Elderly Cohort database between 2008 and 2015. We compared changes in function between the intervention (n = 352) and control (n = 1952) groups before (2014) and after (2015) introduction of the cognitive function training programme. Difference-in-differences analysis was performed, to compare changes in each score between the intervention and control groups before and after introduction of the cognitive function training programme.

Results
introduction of the cognitive function training programme was associated with significantly less cognitive function decline in the intervention group than in the control groups (β = –3.39; standard errors [SE] = 1.14; P = 0.003). A subgroup analysis revealed that this effect increased in subjects in the youngest group, low income bracket, who had a primary caregiver, who were supported in multiple activities of daily living by the primary caregiver, or who were not living alone.

Conclusions
introduction of the cognitive function training programme was associated with positive effects on cognitive function.
New horizons in radiotherapy for older people
Authors: Cree Anthea , O’Donovan Anita , O’Hanlon Shane 
Published: June 2019

Abstract
Radiotherapy is an effective, albeit underutilised, treatment for cancer in older adults, especially for those who are surgically inoperable or for whom chemotherapy poses too great a risk. It is estimated that approximately half of patients with cancer could benefit from radiotherapeutic management. This article synthesises the basics of how radiotherapy works, recent developments in the field and considers how this treatment modality may be adapted in an older patient population or may evolve in the future.
Technological advances of relevance include Intensity Modulated Radiotherapy (IMRT), Volumetric Modulated Arc therapy (VMAT), Stereotactic Ablative Body Radiotherapy (SABR), proton therapy, MR guided radiotherapy, as well as better image guidance during irradiation in order to improve precision and accuracy.
New approaches for better integration of geriatric medicine principles into the oncologic assessment and workup will also be considered, in order to provide more age attuned care. For more informed decision making, a baseline assessment of older radiotherapy patients should encompass some form of Comprehensive Geriatric Assessment. This can facilitate the optimal radiotherapy regime to be selected, to avoid overly toxic regimes in patients with frailty.
The review discusses how these new initiatives and technologies have potential for effective oncologic management and can help to reduce the toxicity of treatment for older adults. It concludes by highlighting the need for more evidence in this patient population including better patient selection and support for treatment to enhance person-centred care.
Anticipating Armageddon: Nuclear Risk and the Neoliberal Sensibility in Thatcher’s Britain
Authors: Boucher Ellen 
Published: June 2019

Abstract
At the height of the “Second Cold War” of the early 1980s, Britons from all walks of life engaged in a wide-ranging public discussion about the likelihood of nuclear Armageddon. Historians have generally understood this cultural conversation as having been motivated by deeply seated fears of nuclear war. This article, however, shifts the focus from fear to risk. It traces the precise ways that British men, women, and children conceptualized the nature of nuclear warfare and debated how its associated risks could be managed. While left-wing activists espoused unilateral disarmament as the best way to alleviate the nuclear threat, a wide swath of the British public turned instead to “self-help” strategies that aligned with the neoliberal ideals of personal autonomy, self-reliance, and individualism. The nuclear risk debate thus reveals the contours of an emerging “neoliberal sensibility” of the period. It also illuminates how the prospect of nuclear war offered Britons a means to articulate and define their expectations of the state amidst Thatcher’s broader prioritization of individual accountability over governmental responsibility.
Embolism resistance in petioles and leaflets of palms
Authors: Emilio Thaise , Lamarque Laurent J , Torres-Ruiz José M , King Andrew , Charrier Guillaume , Burlett Régis , Conejero Maria , Rudall Paula J , Baker William J , Delzon Sylvain 
Published: June 2019

AbstractBackground and aimsHydraulic studies are currently biased towards conifers and dicotyledonous angiosperms; responses of arborescent monocots to increasing temperature and drought remain poorly known. This study aims to assess xylem resistance to drought-induced embolism in palms.MethodsWe quantified embolism resistance via P50 (xylem pressure inducing 50 % embolism or loss of hydraulic conductivity) in petioles and leaflets of six palm species differing in habitat and phylogenetic relatedness using three techniques: in vivo X-ray-based microcomputed tomography, the in situ flow centrifuge technique and the optical vulnerability method.Key resultsOur results show that P50 of petioles varies greatly in the palm family, from −2.2 ± 0.4 MPa in Dypsis baronii to −5.8 ± 0.3 MPa in Rhapis excelsa (mean ± s.e.). No difference or weak differences were found between petioles and leaf blades within species. Surprisingly, where differences occurred, leaflets were less vulnerable to embolism than petioles. Embolism resistance was not correlated with conduit size (r = 0.37, P = 0.11).ConclusionsThis study represents the first estimate of drought-induced xylem embolism in palms across biomes and provides the first step towards understanding hydraulic adaptations in long-lived arborescent monocots. It showed an almost 3-fold range of embolism resistance between palm species, as large as that reported in all angiosperms. We found little evidence for hydraulic segmentation between leaflets and petioles in palms, suggesting that when it happens, hydraulic segregation may lack a clear relationship with organ cost or replaceability.
MutEx: a multifaceted gateway for exploring integrative pan-cancer genomic data
Authors: Ping Jie , Oyebamiji Olufunmilola , Yu Hui , Ness Scott , Chien Jeremy , Ye Fei , Kang Huining , Samuels David , Ivanov Sergey , Chen Danqian , Zhao Ying-yong , Guo Yan 
Published: June 2019

AbstractSomatic mutation and gene expression dysregulation are considered two major tumorigenesis factors. While independent investigations of either factor pervade, studies of associations between somatic mutations and gene expression changes have been sporadic and nonsystematic. Utilizing genomic data collected from 11 315 subjects of 33 distinct cancer types, we constructed MutEx, a pan-cancer integrative genomic database. This database records the relationships among gene expression, somatic mutation and survival data for cancer patients. MutEx can be used to swiftly explore the relationship between these genomic/clinic features within and across cancer types and, more importantly, search for corroborating evidence for hypothesis inception. Our database also incorporated Gene Ontology and several pathway databases to enhance functional annotation, and elastic net and a gene expression composite score to aid in survival analysis. To demonstrate the usability of MutEx, we provide several application examples, including top somatic mutations associated with the most extensive expression dysregulation in breast cancer, differential mutational burden downstream of DNA mismatch repair gene mutations and composite gene expression score-based survival difference in breast cancer. MutEx can be accessed at http://www.innovebioinfo.com/Databases/Mutationdb_About.php.
DEUS: an R package for accurate small RNA profiling based on differential expression of unique sequences
Authors: Jeske Tim , Huypens Peter , Stirm Laura , Höckele Selina , Wurmser Christine M , Böhm Anja , Weigert Cora , Staiger Harald , Klein Christoph , Beckers Johannes , Hastreiter Maximilian 
Published: June 2019

Abstract

Summary
Despite their fundamental role in various biological processes, the analysis of small RNA sequencing data remains a challenging task. Major obstacles arise when short RNA sequences map to multiple locations in the genome, align to regions that are not annotated or underwent post-transcriptional changes which hamper accurate mapping. In order to tackle these issues, we present a novel profiling strategy that circumvents the need for read mapping to a reference genome by utilizing the actual read sequences to determine expression intensities. After differential expression analysis of individual sequence counts, significant sequences are annotated against user defined feature databases and clustered by sequence similarity. This strategy enables a more comprehensive and concise representation of small RNA populations without any data loss or data distortion.

Availability and implementation
Code and documentation of our R package at http://ibis.helmholtz-muenchen.de/deus/.

Supplementary information
Supplementary data are available at Bioinformatics online.
CaPSSA: visual evaluation of cancer biomarker genes for patient stratification and survival analysis using mutation and expression data
Authors: Jang Yeongjun , Seo Jihae , Jang Insu , Lee Byungwook , Kim Sun , Lee Sanghyuk 
Published: June 2019

Abstract

Summary
Predictive biomarkers for patient stratification play critical roles in realizing the paradigm of precision medicine. Molecular characteristics such as somatic mutations and expression signatures represent the primary source of putative biomarker genes for patient stratification. However, evaluation of such candidate biomarkers is still cumbersome and requires multistep procedures especially when using massive public omics data. Here, we present an interactive web application that divides patients from large cohorts (e.g. The Cancer Genome Atlas, TCGA) dynamically into two groups according to the mutation, copy number variation or gene expression of query genes. It further supports users to examine the prognostic value of resulting patient groups based on survival analysis and their association with the clinical features as well as the previously annotated molecular subtypes, facilitated with a rich and interactive visualization. Importantly, we also support custom omics data with clinical information.

Availability and implementation
CaPSSA (Cancer Patient Stratification and Survival Analysis) runs on a web-browser and is freely available without restrictions at http://www.kobic.re.kr/capssa/. The source code is available on https://github.com/yjjang/capssa.

Supplementary information
Supplementary data are available at Bioinformatics online.
Bayesian GWAS with Structured and Non-Local Priors
Authors: Kaplan Adam , Lock Eric F , Fiecas Mark ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: June 2019

AbstractMotivationThe flexibility of a Bayesian framework is promising for GWAS, but current approaches can benefit from more informative prior models. We introduce a novel Bayesian approach to GWAS, called Structured and Non-Local Priors (SNLPs) GWAS, that improves over existing methods in two important ways. First, we describe a model that allows for a marker’s gene-parent membership and other characteristics to influence its probability of association with an outcome. Second, we describe a non-local alternative model for differential minor allele rates at each marker, in which the null and alternative hypotheses have no common support.ResultsWe employ a non-parametric model that allows for clustering of the genes in tandem with a regression model for marker-level covariates, and demonstrate how incorporating these additional characteristics can improve power. We further demonstrate that our non-local alternative model gives symmetric rates of convergence for the null and alternative hypotheses, whereas commonly used local alternative models have asymptotic rates that favor the alternative hypothesis over the null. We demonstrate the robustness and flexibility of our structured and non-local model for different data generating scenarios and signal-to-noise ratios. We apply our Bayesian GWAS method to single nucleotide polymorphisms data collected from a pool of Alzheimer’s disease and cognitively normal patients from the Alzheimer’s Database Neuroimaging Initiative.Availability and implementationR code to perform the SNLPs method is available at https://github.com/lockEF/BayesianScreening.
Economics and ‘bad’ management: the limits to performativity
Authors: Spencer David A 
Published: June 2019

Abstract
The performative power of mainstream economic theories (notably agency theory and transaction cost economics) has been criticised by researchers within management studies. The latter blame these theories for creating ‘bad’ management in real-world organisations and call for their removal from business schools. This paper questions this line of criticism. It argues that mainstream economic theories have condoned more than created ‘bad’ management. It also questions whether ‘bad’ management can be negated by ousting these theories from business schools. Rather it is argued that ‘bad’ management has deep roots within organisations—specifically, it reflects on how organisations are run by and in the interests of capital owners. The possibilities for securing comparatively enlightened or ‘good’ forms of management are seen as necessarily limited by capitalist ownership relations. The paper argues that the transformation of management will require wider reforms in—and importantly beyond—business schools.
Effect of hyperglycaemic conditions on the response of human periodontal ligament fibroblasts to mechanical stretching
Authors: Papadopoulou Adamantia , Todaro Alexia , Eliades Theodore , Kletsas Dimitris 
Published: June 2019

Summary

Objectives
The aim of the present study was to investigate the impact of high glucose concentration on the response of human periodontal ligament fibroblasts (PDLFs) to cyclic tensile strain.

Materials and Methods
Human PDLFs were incubated under normal or high glucose conditions, and then were subjected to cyclic tensile stretching (8 per cent extension, 1 Hz). Gene expression was determined by quantitative real-time polymerase chain reaction. Intracellular reactive oxygen species (ROS) were determined by the 2’,7’-dichlorofluorescein-diacetate assay, activation of mitogen-activated protein kinase (MAPK) was monitored by western analysis and osteoblastic differentiation was estimated with Alizarin Red-S staining.

Results
Cyclic tensile stretching of PDLF leads to an immediate activation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK), as well as to the increased expression of the transcription factor c-fos, known to regulate many osteogenesis-related genes. At later time points, the alkaline phosphatase and osteopontin genes were also upregulated. Hyperglycaemic conditions inhibited these effects. High glucose conditions were unable to increase ROS levels, but they increased the medium’s osmolality. Finally, increase of osmolality mimics the inhibitory effect of hyperglycaemia on MAPK activation, c-fos and osteoblast-specific gene markers’ upregulation, as well as osteogenic differentiation capacity.

Conclusion
Our findings indicate that under high glucose conditions, human PDLFs fail to adequately respond to mechanical deformation, while their strain-elicited osteoblast differentiation ability is deteriorated. The aforementioned effects are most probably mediated by the increased osmolality under hyperglycaemic conditions.