bluuebunny/crossref_metadata_2025_split huggingface dataset:
INTERLEUKIN LEVELS IN PATIENTS WITH ESSENTIAL HYPERTENSION COMBINED WITH TYPE 2 DIABETES MELLITUS
Authors: Shelest B.O. 
Published: June 2019

INTERLEUKIN LEVELS IN PATIENTS WITH ESSENTIAL HYPERTENSION COMBINED WITH TYPE 2 DIABETES MELLITUSShelest B.O.The problem of combined course of hypertension of diabetes mellitus type 2 and obesity is becoming more common. This variant of comorbidity crucially increases the risk of cardiovascular complications. Inflammation is considered as an important link between the progression of hypertension and the development of adverse events. This study is devoted to the question of the relationship between the pro-inflammatory marker interleukin-6 and the increased blood pressure in patients with concomitant diabetes and obesity. The treatment of such patients with combined pathology remains the actual and difficult issue of medical practice. The article analyses the dynamics of interleukin-6 in the process of treatment with a fixed triple antihypertensive combination. Key words: hypertension, interleukin-6, type 2 diabetes mellitus, obesity. РІВНІ ІНТЕРЛЕЙКІНІВ У ХВОРИХ НА ГІПЕРТОНІЧНУ ХВОРОБУ У ПОЄДНАННІ З ЦУКРОВИМ ДІАБЕТОМ 2 ТИПУ Шелест Б.О.Все більшого поширення набуває проблема поєднаного перебігу гіпертензії цукрового діабету 2 типу та ожиріння. Такий варіант коморбидности різко підвищує ризик кардіоваскулярних ускладнень. Важливою ланкою в прогресуванні гіпертензії і розвитку несприятливих подій відводиться запаленню. Дана робота присвячена питанню залежності прозапального маркера інтерлейкіну-6 і підвищених цифр артеріального тиску у хворих з супутнім цукровим діабетом 2 типу і ожирінням. Актуальним і складним питанням медичної практики залишається лікування таких пацієнтів з поєднаною патологією. У статті аналізується динаміка інтерлейкіну-6 в процесі лікування потрійною фіксованою антигіпертензивною комбінацією.Ключові слова: гіпертонічна хвороба, інтерлейкін-6, цукровий діабет 2 типу, ожиріння. УРОВЕНЬ ИНТЕРЛЕЙКИНОВ У ПАЦИЕНТОВ С ГИПЕРТОНИЧЕСКОЙ БОЛЕЗНЬЮ В СОЧЕТАНИИ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА. Шелест Б.А.Все большее распространение приобретает проблема сочетанного течения гипертензии сахарного диабета 2 типа и ожирения. Такой вариант коморбидности резко повышает риск кардиоваскулярных осложнений. Важным звеном в прогрессировании гипертензии и развитии неблагоприятных событий отводится воспалению. Даннаяработапосвящена вопросу зависимости провоспалительного маркера интерлейкина-6 и наличием повышенных цифр артериального давления у больных с сопутствующим сахарным диабетом и ожирением. Актуальным и сложным вопросом медицинской практики остается лечение таких пациентов с сочетанной патологией. В статье анализируется динамика интерлейкина-6 в процессе лечения фиксированной тройной антигипертензивной комбинацией. Ключевые слова: гипертоническая болезнь, интерлейкин-6, сахарный диабет 2 типа, ожирение.
Fluid Dynamic Aspects of Protostellar Disks Formation
Authors: Capitaine Gérard 
Published: June 2019

Abstract
An analysis is presented of fluid dynamic aspects of the interaction between a disk and the infall of material from a surrounding non-magnetized rotating molecular cloud. The study put emphasis on the accretion shock formed in the vicinity of the disk and the post-shock flow field. This post-shock flow is considered parallel to the disk symmetry plane involving a super-Keplerian azimuthal velocity field v ∼ 1/r (potential vortex). The relative rotation between fluid and the nearly Keplerian rotating thin disk induces along its symmetry plane a boundary layer capable of transporting large quantities of fluid inward. This radial flow results in an axial flow i.e., a mass ejection from the boundary layer with axial jet flow velocities of up to about 300 km s−1.
Millisecond Pulsars and Black Holes in Globular Clusters
Authors: Ye Claire S. , Kremer Kyle , Chatterjee Sourav , Rodriguez Carl L. , Rasio Frederic A. 
Published: June 2019

Abstract
Over 100 millisecond radio pulsars (MSPs) have been observed in globular clusters (GCs), motivating theoretical studies of the formation and evolution of these sources through stellar evolution coupled to stellar dynamics. Here we study MSPs in GCs using realistic N-body simulations with our Cluster Monte Carlo code. We show that neutron stars (NSs) formed in electron-capture supernovae (including both accretion-induced and merger-induced collapse of white dwarfs) can be spun up through mass transfer to form MSPs. Both NS formation and spin-up through accretion are greatly enhanced through dynamical interaction processes. We find that our models for average GCs at the present day with masses ≈2 × 105
M
⊙ can produce up to 10–20 MSPs, while a very massive GC model with mass ≈106
M
⊙ can produce close to 100. We show that the number of MSPs is anti-correlated with the total number of stellar-mass black holes (BHs) retained in the host cluster. The radial distributions are also affected: MSPs are more concentrated toward the center in a host cluster with a smaller number of retained BHs. As a result, the number of MSPs in a GC could be used to place constraints on its BH population. Some intrinsic properties of MSP systems in our models (such as the magnetic fields and spin periods) are in good overall agreement with observations, while others (such as the distribution of binary companion types) are less so, and we discuss the possible reasons for such discrepancies. Interestingly, our models also demonstrate the possibility of dynamically forming NS–NS and NS–BH binaries in GCs, although the predicted numbers are very small.
The critical role of abiotic factors and human activities in the supply of ecosystem services in the ES matrix
Authors: Maebe Laura , Claessens Hugues , Dufrêne Marc 
Published: June 2019

In Western Europe, ecosystems have been shaped to maximise the supply of one specific biomass provisioning ecosystem service (ES), such as food or timber, with detrimental impacts on other ES. The ES approach has therefore been established to better understand the multiple interactions between human society and ecosystems. A variety of methods have been developed to assess ES and their relationships, for instance the ES matrix model based on land cover classes. This popular, flexible and simple method allows combining different data sources and easily comparing ES. However, in general, this method poorly takes into account landscape heterogeneity while abiotic factors and human activities seem to play an important role in ES supply. The objective of this paper is twofold: (1) to extent the methodology based on the ES matrix model by including abiotic factors and human activities and (2) to test the impacts of these two types of factors on ES supply and their relationships.
The assessment focused on the capacity of the forest to supply six ES depending on six types of soil ranging from productive soils to more constraining or less productive soils (i.e. abiotic factors) and two contrasting forest management strategies (i.e. human activities). This amended ES matrix was applied on one hand, to map the supply of ES and their relationships in four municipalities in the Ardenne ecoregion (Southern Belgium) and on the other hand, to investigate the impacts of three scenarios (i.e. three different management strategies) on ES supply and their relationships.
The amended ES matrix shows large differences in ES supply between the two forest management strategies on the more constraining and less productive soils, creating differences in the spatial pattern of ES. The changes in ES supply amongst the three scenarios and the current supply were quantified to identify the best management options.
In conclusion, one particular forest is not like another in terms of ES supply and their relationships. To capture this heterogeneity, we propose an amended ES matrix including abiotic factors and human activities. The maps, based on this matrix, allow identifying the hotspots (i.e. high capacity to supply different ES) and coldspots (i.e. low capacity to supply different ES or strong trade-offs between provisioning ES and regulating/cultural ES). Forest management should be adapted to the abiotic conditions, in particular in the coldspots, to ensure a more balanced supply of ES.
Conceptual Frameworks in Undergraduate Nursing Curricula: Report of a National Survey
Authors: McEwen Melanie , Brown Sandra C 
Published: June 2019

ABSTRACT
A national survey was conducted to analyze the components of conceptual frameworks to assess how they are being used to organize the curricula of nursing programs and to determine whether there was a difference among types of programs (i.e., baccalaureate degree, associate degree, diploma). A stratified, random sample of 300 National League for Nursing Accrediting Committeeaccredited schools of nursing was selected based on percentages of each type of program. Questionnaires were returned from 160 programs.
The survey found that the conceptual frameworks of most nursing programs were eclectic and that the nursing process was the most commonly cited component for all types of programs. Significant differences were identified among the three types of programs in their use of simpleto-complex organization, the medical model, and the nursing process. Significant differences also were identified among the three types of programs in incorporation of the metaparadigm concepts of nursing, person, health, and environment, and the emphasis placed on critical thinking, problem solving, and therapeutic nursing interventions.
Equipamentos de saúde e processos de atenção: Tópicos para pensar ações do Estado voltadas aos povos indígenas
Authors: Silveira Nádia Heusi 
Published: June 2019

Este artigo aborda a ação do Estado tendo em vista o processo de discussão de uma política intersetorial direcionada ao problema do uso de álcool e drogas entre os Kaiowa e Guarani. Os agentes envolvidos realizaram uma serie de encontros e debates para consensuar diretrizes de ação, tendo como um dos eixos de debate a instalação ou não de Centro de Atenção Psicossocial Álcool e Drogas (CAPS AD) na Reserva Indígena de Dourados. Considerando convergências e divergências de pontos de vista a partir da unanimidade sobre a necessidade de implementar uma ação articulada entre vários órgãos de governo, o caráter desses encontros é analisado considerando a perpetuação do poder tutelar.
Extracellular Polyphosphate Promotes Macrophage and Fibrocyte Differentiation, Inhibits Leukocyte Proliferation, and Acts as a Chemotactic Agent for Neutrophils
Authors: Suess Patrick M. , Chinea Luis E. , Pilling Darrell , Gomer Richard H. 
Published: June 2019

AbstractFibrocytes are monocyte-derived fibroblast like cells that participate in wound healing, but little is known about what initiates fibrocyte differentiation. Blood platelets contain 60–100-mer polymers of phosphate groups called polyphosphate, and when activated, platelets induce blood clotting (the first step in wound healing) in part by the release of polyphosphate. We find that activated platelets release a factor that promotes fibrocyte differentiation. The factor is abolished by treating the crude platelet factor with the polyphosphate-degrading enzyme polyphosphatase, and polyphosphate promotes fibrocyte differentiation. Macrophages and recruited neutrophils also potentiate wound healing, and polyphosphate also promotes macrophage differentiation and induces chemoattraction of neutrophils. In support of the hypothesis that polyphosphate is a signal that affects leukocytes, we observe saturable binding of polyphosphate to these cells. Polyphosphate also inhibits leukocyte proliferation and proteasome activity. These results suggest new roles for extracellular polyphosphate as a mediator of wound healing and inflammation and also provide a potential link between platelet activation and the progression of fibrosing diseases.
Value Sets of Sparse Polynomials
Authors: Shparlinski Igor E. , Voloch José Felipe 
Published: June 2019

AbstractWe obtain a new lower bound on the size of the value set$\mathscr{V}(f)=f(\mathbb{F}_{p})$of a sparse polynomial$f\in \mathbb{F}_{p}[X]$over a finite field of$p$elements when$p$is prime. This bound is uniform with respect to the degree and depends on some natural arithmetic properties of the degrees of the monomial terms of$f$and the number of these terms. Our result is stronger than those that can be extracted from the bounds on multiplicities of individual values in$\mathscr{V}(f)$.
Gambling Among Emerging Adults: How Gender and Risk Level Influence Associated Problem Behaviours
Authors: Sanscartier Matthew D , Shen Jack , Edgerton Jason D 
Published: June 2019

This study investigates mental health and substance use problems associated with gambling among Canadian emerging adults (ages 18–20 years). Drawing on a cross-sectional wave of 624 (47.8% male) participants from the Manitoba Longitudinal Study of Young Adults, our findings suggest that among emerging adults, problem gambling should be understood as part of a wider syndrome. The profile of syndromic associations varies with both problem gambling risk level and gender. With respect to risk level, regression models indicate that, relative to no-risk gamblers, lower risk gamblers are more likely to use drugs and alcohol, whereas higher risk gamblers report greater symptoms of depression and anxiety. Males and females present different barriers to recovery: High-risk female gamblers are more likely to rely on escape-avoidance coping mechanisms, whereas their male counterparts tend to lack perceived social support. Given the centrality of these two variables and the lack of literature addressing how they interact, we conclude that further research is needed to understand how gender and gambling severity interact to simultaneously influence gambling-related behaviours among emerging adults. RésuméCette étude porte sur les problèmes de santé mentale et de toxicomanie associés au jeu chez les jeunes adultes canadiens (âgés de 18 à 20 ans). Fondés sur une vague transversale de 624 participants (47,8% d’hommes) de l’étude longitudinale des jeunes adultes du Manitoba (MLSYA), nos résultats laissent entendre que, parmi les jeunes adultes, le jeu problématique devrait être abordé comme faisant partie d’un syndrome plus vaste. Le profil des associations syndromiques varie selon le niveau de risque de jeu problématique et le genre. En ce qui concerne le niveau de risque, les modèles de régression indiquent que, par rapport aux joueurs sans risque, les joueurs à faible risque sont plus susceptibles de consommer de la drogue et de l’alcool, tandis que les joueurs à risque plus élevé montrent des symptômes plus importants de dépression et d’anxiété. En parallèle, les hommes et les femmes rencontrent différents obstacles au rétablissement : les joueuses à haut risque sont plus susceptibles de compter sur des mécanismes d’adaptation comme l’échappement ou l’évitement, tandis que leurs homologues masculins ont tendance à manquer de soutien social perçu. Compte tenu de la centralité de ces deux variables et du manque de littérature traitant de leurs interactions, nous concluons qu’il est nécessaire de poursuivre les recherches pour comprendre les interactions entre le genre et la gravité du jeu pathologique afin d’influencer simultanément les comportements liés au jeu chez les jeunes adultes.
La participación ciudadana en el combate contra la corrupción: Un análisis desde la carga de prevenir el daño en el panorama jurídico colombiano
Authors: Gallo Aponte William Iván 
Published: June 2019

El fenómeno de la corrupción penetra en lo más profundo de la conciencia de los pueblos, obstruyendo la estabilidad de las instituciones, el desarrollo económico y el progreso social. Por esta razón, es una
preocupación latente desde diferentes latitudes, y particularmente en Colombia. En este sentido, la actuación de los agentes públicos para contrarrestarla no es suficiente, por lo que se ve la necesidad de una activa participación e intervención ciudadana, que, además, constituye uno de los pilares del Derecho Administrativo contemporáneo. De esta manera, a través de un análisis de la carga de prevenir o mitigar el daño antijurídico, tanto en el derecho privado como en la contratación estatal, y con una presentación de los diferentes escenarios, instrumentos
y garantías a través de los cuales se desarrolla la participación ciudadana, se propone y justifica el empoderamiento de la población civil en el desarrollo de las actividades públicas para combatir la corrupción.
Interventions to address medication-related causes of hospital readmissions: A scoping review
Authors: Carroll Nathan W. , Joseph Reena , Puro Neeraj 
Published: June 2019

Unplanned readmissions pose a tremendous burden on patients, providers, and payers. A significant proportion of readmissions are medication-related. Despite the availability of literature regarding hospital-level strategies to reduce readmissions, little has been written about strategies aimed at medication-related readmissions. We sought to identify successful readmission reduction strategies by performing a scoping literature review of research published between 2000 and 2017. We identified 21 studies that met our inclusion criteria. From these studies, we identified 7 components frequently employed as a part of interventions to reduce medication-related readmissions: discharge planning, discharge education, post-discharge telephone calls, the use of a professional coordinator with clinical training to administer the intervention, patient education efforts, provider training efforts, and medication reconciliation. Thirty-eight percent of all the interventions identified were associated with a statistically significant reduction in readmissions. Of the 7 common intervention components we identified, none were consistently associated with intervention success in the full sample. However, interventions implemented by inpatient hospitals, in particular academic medical centers, had a higher success rate than interventions implemented by other providers. We examined a subsample of larger studies and found that discharge planning and medication reconciliation components were included in most of the successful interventions. Future research should look beyond simply identifying components included in an intervention and should instead seek to identify contextual factors that enable or inhibit the success of these components. Research examining discharge planning and medication reconciliation efforts will be particularly important.
AGRICULTURE IN THE FACE OF CLIMATE CHALLENGES – THE PROBLEM OF GREENHOUSE GAS EMISSIONS
Authors: Pondel Hanna 
Published: June 2019

Changes in seasonal weather cycles, a growing number of extreme phenomena, an upward trend in temperature and changes in the distribution of rainfall, significantly affect the functioning and effectiveness of agriculture. However, agriculture plays a major role in the emergence and intensification of these phenomena. The aim of the article is to present, analyse and evaluate the relations between agriculture and climate, with particular emphasis on greenhouse gas (GHG) emissions from agriculture in these relations. A cause-and-effect analysis was conducted based on literature studies, using the descriptive statistics method and analysis of the development trend. The basis for analysis were data on GHG emissions in the European Union (EU-28). The contribution of agriculture to the EU’s greenhouse gas emissions, albeit slightly but still increasing in recent years. The level of this emission is determined primarily by the type of agricultural activity conducted – animal production is definitely responsible for higher emissions than plant production. It is difficult to present a universal model of agricultural adaptation to climate change and a set of actions limiting the negative impact of agricultural production on climate. This is hindered by both the specificity of the agricultural sector and the large diversity of local conditions and applied farming practices. The opportunity to increase the effectiveness of actions taken may be a better connection between the implementation of objectives including the reduction of the causes and negative consequences of climate change and the objectives of sustainable agricultural development.
Sequencial luminoso controlado por Bluetooth
Authors: Reis Amanda Wohlfahrt , Iaronk Odair José , Tischer Celso Becker 
Published: June 2019

A utilização de microcontroladores teve crescimento nos últimos anos no desenvolvimento de sistemas eletrônicos devido a suas pequenas dimensões e capacidade de controlar processos. A aplicação de microcontroladores é significativa em diversos setores, tais como: industrias, residencial, entretenimento, telecomunicações, automotivas, transporte e aviação. O arduino é uma plataforma eletrônica de baixo custo, open source, de prototipagem projetada com um microcontrolador embutido baseado em hardware e software de fácil utilização, que pode ser programada a fim de configurar as entradas e saídas entre os componentes externos conectadas a plataforma. Assim, visando a transformação do entretenimento em uma forma de aprendizagem, este trabalho apresenta o desenvolvimento de um sequencial luminoso baseado em arduino programado em linguagem C. O sistema é composto por 25 LED’s distribuídos de forma estratégica para a visualização das sequencias pré-programadas. No projeto utilizou-se o arduino MEGA 2560 e um módulo Bluetooth para comunicação sem fio entre o microcontrolador e dispositivos multifuncionais como smartphone’s, um aplicativo desenvolvido no MIT APP INVENTOR controla o sistema, proporcionando ao usuário a capacidade de escolha da rotina além da velocidade e intensidade luminosa do conjunto.
Alt er sandt!
Authors: Zirak-Schmidt David Hasberg 
Published: June 2019

David Hasberg Zirak-Schmidt: “All is true! Memory, Oblivion and History in Shakespeare and Fletcher’s Henry VIII”
In this article I examine the dialectic of memory and oblivion in Shakespeare and Fletcher’s history play Henry VIII. Taking off from a close reading of the ambivalent apotheosis of Catherine of Aragon, the article argues that Henry VIII questions the relationship between fiction and historical truth. Through this process, I argue, that the play self-consciously reflects on the theater’s role and ability as a transmitter of historical knowledge and truth.
Middelalderens hang til det overnaturlige
Authors: Csúr Gábor Attila 
Published: June 2019

Gábor Attila Csúr: “The Inclination to the Supernatural in the Middle Ages – A Critical Reading of Medieval Religiousness in Danish Historical Novels”
The article focuses on Danish historical prose fiction from the last two centuries and analyzes how the phenomenon ‘medievalism’, i. e. the interpretation, reception and recreation of the Middle Age, has changed during this period. Stereotypes about medieval religious thought and belief and the role of the church have always been popular features of historical novels. By analyzing the depictions of religiousness, the article attempts to draw a line of development in understanding medieval culture and everyday life.