bluuebunny/crossref_metadata_2025_split huggingface dataset:
ВИКОРИСТАННЯ КРИПТОВАЛЮТИ З МЕТОЮ ЛЕГАЛІЗАЦІЇ КОШТІВ, ЗДОБУТИХ ЗЛОЧИННИМ ШЛЯХОМ: БІБЛІОМЕТРИЧНИЙ АНАЛІЗ
Authors: БОГДАН Едуард 
Published: November 2024

У статті проведено аналіз наукових публікацій щодо використання криптовалют для легалізації коштів, здобутих злочинним шляхом, через бібліометричний підхід та виявлено основні тенденції в науковому дискурсі, включно з найважливішими авторами, джерелами, тематиками та країнами, що активно досліджують цю проблему. Методологія дослідження передбачає проведення бібліометричного аналізу за допомогою бази даних Scopus і програмного забезпечення Biblioshiny для визначення основних тенденцій у наукових публікаціях, ідентифікації провідних авторів, журналів та ключових тем. Результати аналізу показують, що з 2016 року кількість досліджень на цю тему стрімко зросла, що свідчить про посилений інтерес наукової спільноти до фінансових злочинів, пов'язаних із криптовалютами. Найбільшу кількість публікацій розміщено в таких журналах, як Journal of Money Laundering Control та Journal of Financial Crime. Середня кількість цитувань на одну статтю становить 10,95, що свідчить про великий інтерес до теми.У той же час, найбільш цитовані роботи стосуються питань анонімності криптовалют, регуляторних викликів та технологічних інновацій у виявленні підозрілих транзакцій. Близько 17% документів мають міжнародне співавторство, що свідчить про необхідність глобальних зусиль для вирішення питань фінансових злочинів через криптовалюти. Дослідження вперше узагальнює науковий дискурс з теми відмивання грошей через криптовалюти на основі великої кількості публікацій. Це дозволяє виявити ключові теми, авторів та джерела, які домінують у цій сфері, та встановити, як дослідження розвивалося з часом. Практична значущість результатів дослідження полягає в тому, що вони можуть бути використані для вдосконалення регуляторних та правових механізмів, спрямованих на боротьбу з фінансовими злочинами, зокрема відмиванням коштів через криптовалютні мережі.
Strategi Bersaing d'BestO dan Sabana di Era Digitalisasi Pasar dalam Perspektif Konsumen
Authors: Kholik Muhammad Imam Akbar , Fadhila Muhammad Nauval , Adji Muhammad Irvansyah Putra , Alfitrah Muhammad Firzy , Zidan Ibnu , Aminda Renea Shinta , Ariani Maria Bernadette Nani 
Published: November 2024

Era digital terus-menerus berkembang dengan seiring waktu. Perkembangan ini tentu saja tidak dapat dihindari oleh manusia sehingga manusia harus mengikuti arus perkembangan digital. Industri e-commerce menjadi salah satu sektor yang berkembang pesat. Maka dari itu untuk bisa berhasil dalam persaingan para pelaku usaha atau perusahaan e-commerce harus memiliki strategi pemasaran yang efektif agar menarik dan mempertahankan pelanggan. Di era digital seperti sekarang membuat informasi lebih cepat dan juga akurat, oleh karena itu banyak sekali jenis usaha yang ada. Disini kelompok kami memilih d'BestO dan sabana menjadi bahan penelitian karena sudah banyaknya UMKM mikro maupun makro yang berjualan fried chicken. Oleh karena itu Penelitian ini untuk mengetahui strategi pemasaran yang dilakukan oleh para pelaku usaha d'BestO dan Sabana yang bersaing dalam era digitalisasi pasar dalam perspektif konsumen. Disini kami melakukan penelitian dengan menggunakan pendekatan kuantitatif melalui kuesioner secara terstruktur terhadap konsumen d'BestO dan Sabana. Dari hasil penelitian penerapan teknologi dalam industri kuliner juga mendapatkan respon positif bagi para konsumen.
Analisis Faktor yang Mempengaruhi Konsumsi Daging di Pulau Jawa
Authors: Reza Umamah  , Vikko Hilmi Pradana  , Nesya Zuhrah  , Heikelindra Kurniawan  , Silva Syalikha  
Published: November 2024

Konsumsi biasanya diartikan sebagai penggunaan barang dan jasa yang secara langsung akan memenuhi kebutuhan manusia. Seseorang harus memperoleh pendapatan untuk dapat mengkonsumsinya, dan besar kecilnya pendapatan sangat mempengaruhi tingkat konsumsinya. Masyarakat Indonesia biasanya mengonsumsi daging sapi pada hari raya dan hari raya keagamaan, khususnya di daerah pedesaan. Penelitian ini membahas tentang bagaimana faktor-faktor yang dapat mempengaruhi konsumsi daging sapi di Pulau Jawa. Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh Faktor-faktor yang ada, dalam penelitian ini membahas tiga faktor yaitu harga daripada daging sapi tersebut, jumlah penduduk dan juga dari faktor Produk Domestik Regional Bruto (PDRB). Peneliti menganggap ketiga faktor ini memberikan pengaruh yang cukup besar terhadap tingkat konsumsi daging sapi di Pulau Jawa. Data yang dianalisis dalam penelitian ini berasal dari web resmi Badan Pusat Statistik (BPS), data faktor-faktor yang akan dianalisis mencakup periode 2020 hingga tahun 2023. Penelitian ini memberikan sebuah fakta baru bahwa faktor yang paling signifikan pengaruhnya adalah faktor harga daging sapi, harga daging sapi menjadi faktor yang paling berpengaruh terhadap konsumsi daging sapi di Pulau Jawa.
Revisión bibliográfica del efecto de la adición de estiércol bovino en la producción agrícola
Authors: Paredes Peralta Armando Vinicio , Guzmán Brito Zoila Rosa 
Published: November 2024

Introducción: el uso de estiércol bovino como abono orgánico, es una excelente alternativa para disminuir la utilización irrazonable de fertilizantes químicos, su aplicación en la producción agrícola brinda importantes beneficios tanto desde el punto de vista económico como en la producción de los diferentes cultivos. Objetivo: el propósito del presente estudio de revisión bibliográfica fue investigar el efecto de la adición de estiércol bovino en la producción agrícola. Metodología: se recopiló información de fuentes bibliográficas confiables utilizando buscadores tales como Google académico, PubMed, Scopus, entre otros. Diferentes estudios indican que la incorporación de estiércol bovino en un suelo mejora su estructura y agrega una cantidad sustancial de materia orgánica. Resultados: el mayor contenido de materia orgánica alcanzada fue de 59.61%, y en nitrógeno fue de 2.78%, así mismo, las investigaciones indicaron que dosis elevadas de estiércol bovino influye de manera negativa en algunas propiedades como la conductividad eléctrica, donde se consiguió valores de 3.6- 4.3 dS/m, resultados que fueron mayores a los que se consiguió en un suelo sin la aplicación de estiércol bovino. Conclusiones: Las diferentes investigaciones revelaron que el estiércol bovino, cuando se utiliza como fertilizante orgánico, mejora la productividad de los cultivos, hasta el punto de superar a los fertilizantes químicos. Área de estudio: Ciencia y Tecnología. Área de estudio específica: Agropecuaria. Tipo de estudio: revisión bibliográfica.
Strategic Localization for Ukraine's Defense Industry
Authors: McCarthy Michael J. , Yemchura Taras 
Published: November 2024

Purpose: to evaluate the options for strategic localization for the defence industrial sector of Ukraine and to provide practical recommendations for the implementation of the policy.
Method: comparative analysis, synthesis, and case studies.
Findings: Rebuilding Ukraine’s degraded defence industry is vital for its long-term security and strategic interests, and a robust Ukrainian defence industry supports partner nation security interests as well. While continued foreign assistance remains essential in the short term, Ukraine needs to progressively localize repair, assembly, and repair capabilities for its most critical military equipment.
Theoretical implications: The paper enhances our understanding of key concepts relating to the contributions of the local defence industry to the security of Ukraine, and how those industries can be developed to support the capabilities of the Armed Forces of Ukraine. The Russia-Ukraine war serves as a contemporary case study to explore these theories in practice. The paper provides new insights for understanding the practical application of the policy of localization.
Value: Examining the practical implications of the policy of localization in Ukraine’s defence industry in the context of the Russia-Ukraine war involves understanding how these theories translate into real-world recommendations, both for Ukraine and for its international partners. that can contribute to the development and sustainment of Ukraine’s military capabilities.
Research limitations: The classification of much information relating to Ukraine’s defence industry and defence capabilities, along with the contributions of international partners, forms a limitation on the scope and depth of the study.
Russian multicenter observational HDQ study on the validation of the questionnaire for hemorrhoidal disease
Authors: Shelygin Yu. A. , Stoyko Yu. M. , Kostarev Ivan V. , Zagriadskiǐ E. A. , Bogomazov A. M. , Golovko E. B. , Khomitskaya Yu. V. , Kvasnikov B. B. , Linnik O. Zh. 
Published: November 2024

AIM: to develop and validate hemorrhoidal disease (HD) specific national questionnaire.MATERIALS AND METHODS: the Russian questionnaire, which included questions on the most typical HD symptoms, was developed by leading national specialists-proctologists. The regression analysis was used to evaluate linear and nonlinear relationships between the fact of the HD presence, objectively confirmed by a doctor, and the patients’ answers to the questions from the questionnaire. The final version of the questionnaire included only questions regarding clinical characteristics typical for hemorrhoids that were significantly associated with the presence of the disease. Validation of the questionnaire was performed on both training and test samples of patients to determine its sensitivity (Se) and specificity (Sp) in identifying patients with HD.RESULTS: initially, 7 main domains reflecting the presence and severity of symptoms typical for HD were included in the questionnaire. A training sample of patients was used to search for linear and nonlinear relationships between objectively confirmed hemorrhoids and responses to questions in the initial questionnaire. The final version of the questionnaire, consisting only of questions regarding symptoms that have demonstrated to be significant predictors of hemorrhoids, was validated on a training sample (Se = 86.5%, Sp = 73.4%, and the probability of identifying a patient with HD, according to Bayes’ theorem = 66.6%). After the developed version of the questionnaire was validated on a test sample, the final screening questionnaire for HD demonstrated Se 83.7%, Sp 74.1%, and the probability of identifying patients with HD with a positive questionnaire result, calculated according to Bayes’ theorem, was 67%.CONCLUSION: the first national questionnaire for screening HD has diagnostic characteristics indicating its high accuracy in identifying patients with HD and allowing it to be recommended for use in the general population.
Rectal foreign bodies. Diagnostic program and emergency care
Authors: Egorkin M. A. , Bolkvadze E. E. , Obukhov V. K. , Gorbunov I. N. , Evloeev M. Ya. 
Published: November 2024

AIM: to estimate clinical approaches to rectal foreign bodies (RFBs).PATIENTS AND METHODS: the retrospective cohort study included 47 patients (2022-2024) with suspected RFBs. Two clinical cases are presented. Case No. 1. Patient N., a 41-year-old male, was presented with RFB (a glass tumbler), introduced into the rectum without his consent. Because of RFB migration to the upper parts of the colon and risk of the intestinal perforation a laparotomy with removal of the intact foreign body was done. Case No. 2. Patient A, a 26-year-old male, was presented with RFB (a 80.0 × 7.0 cm dildo) that was transanally removed in the emergency room without anesthesia. No post-op complications developed. No any literature data of successful transanal removal of a larger RFB was found [1–5].RESULTS: out of 47 patients, the manual transanal removal of RFBs was successful in 46 (97.9%) cases. One (2.1%) patient required laparotomy due to the high risk of rectal injury and retrograde migration of RFB to the proximal colon. A variety of RFBs (size, shape, and material), an individual, structured approach to the diagnosis and treatment is required.CONCLUSION: clinical approach to RFBs depends on risk of intestinal perforation.
Prediction of anorectal dysfunction in the combined treatment of rectal cancer
Authors: Bondarenko O. K. , Gevorkyan Yu. A. , Soldatkina N. V. , Gusareva M. A. , Kosheleva N. G. , Petrov D. S. , Savchenko D. A. , Rozenko L. Y. , Kit O. I. 
Published: November 2024

AIM: to assess the risk of severe low anterior resection syndrome (LARS) in patients with rectal cancer after combined treatment.PATIENTS AND METHODS: from July 2022 to November 2023, 50 patients with rectal cancer underwent radiation with a total focal dose of 50–54 Gy with radiomodification with capecitabine and low anterior rectal resection with preventive ileostomy. The ileostomy was closed after 4 months. Prior to and after radiation, the anorectal function was assessed using high-resolution anorectal manometry (HRAM) and the LARS scale.RESULTS: the most significant predicting factors for severe LARS were maximal contraction pressure and first sensation volume. Three months after ileostomy closure, the patients were divided into groups depending on the HRAM parameters. Group 1: nine patients with severe LARS (34 points on the LARS scale), with a decrease in maximal contraction pressure by ≥ 30% and an increased first sensation volume by ≥ 60%, according to HRAM. Group 2: four patients out of 36 had severe LARS (31 points on the LARS scale), with a decrease in maximal contraction pressure by 5–29% and an increased first sensation volume by 10–59%, according to HRAM. Group 3: in 5 patients with a decreased maximal contraction pressure by ≤ 4% and an increased volume of the first sensation by ≤ 9%, LARS did not develop.CONCLUSION: a decrease in the maximal contraction pressure by 30% or more and an increase in the volume of the first sensation by 60% or more after radiation therapy can increase the risk of severe LARS. This group of patients requires prevention and correction of anorectal dysfunction.
Risk for nitrogen leaching after application of solid manure in autumn differs between manure types
Authors: Delin Sofia , Mårtensson Kristina , Johnsson Holger 
Published: November 2024

Manure application performed in autumn requires regulation due to the risk of nitrogen (N) leaching during winter. On the other hand, application of manure in spring can pose some practical problems depending on the risk for N immobilization and the difficulty in ploughing heavy clay soils during this time of year. The risk for leaching is likely to differ between different soil texture and manure characteristics. In this study, we sought to estimate the risk for nitrogen leaching depending on the carbon/nitrogen ratio (C/N) of the manure, time for manure application, and soil type. We combined 3-year lysimeter experiments with 2-year field plot experiments and laboratory soil incubations and compared results with those from an empirical model. We compared effects of manure application on two soils (silty clay and loamy sand) and solid manures with different representing C/N ratios. In incubations, only manure with a C/N-ratio below 14 contributed with significant amounts of leachable N during the first months after application. In the lysimeter study, N leaching was unaffected by the timing of the application of the manure with C/N-ratio 18. However, regarding manure with C/N-ratio 10, N leaching was elevated with 10–15 kg N per ha after manure application in October compared to November and March on both soil types. The mineral N analyses from soil profiles in the field experiments showed a similar pattern, however, the increase was higher on the loamy sand compared to the silty clay. The ammonia emissions did not differ between manure types, but were on average 24% of applied NH4-N after application in October when air temperature was on average 12°C compared to only 3% of applied NH4-N in November and March when air temperature was on average 5°C. Similar to lysimeter results, the modelled N leaching was higher the earlier the manure application occurred in autumn. However, the model also predicted increased leaching for the manure with a high C/N-ratio, and a smaller effect on leaching on clay soil. Considering this, the model calculations overestimated the leaching effects from manure with a high C/N-ratio and underestimated the leaching effects on clay soil.
The variant c.274A>G (p.Asn92Asp) in KRT17 in a patient with pachyonychia congenita and a novel clinical feature of acne inversa
Authors: Wang Huaiyu , Zhu Changhua , Dong Linxin , Wu Baofeng , Liu Jingjing , Lin Lihang , Lin Daoyao , Chen Xiangqi , Xiao Xuemin 
Published: November 2024

IntroductionThe occurrence of pachyonychia congenita (PC) and acne inversa (AI) may be related to gene mutations. The aim of this study is to identify the genetic cause in a patient with PC and AI, and to explore the possible molecular mechanism of their co-occurrence.MethodsThe clinical data of the proband were collected, and the genomic DNA of the proband and unaffected parents were extracted. The variant sites of the proband were identified by whole-exome sequencing, and then the variant sites of the proband and his parents were verified by Sanger sequencing.ResultsA heterozygous variant in KRT17 gene was found in the patient, resulting in a missense amino acid variant (p.N92D). The variant was not found in his parents or 100 unrelated healthy controls. In addition, this variant was not found in the gnomad v4 database. The three-dimensional structure analysis of the protein suggested that the polarity of amino acids changed after the variant. After lentiviral plasmid transfection into HaCaT cells, the expression level of NOTCH signaling decreased in the constructed c.274A&gt;G (p.Asn92Asp) of KRT-17 mutant cells compared to that in the wild-type. Subsequent verification confirmed that differences in the expression levels of p-PI3K, AKT and p-AKT between the groups were not statistically significant.DiscussionAlthough this variant has been reported previously, our findings could expand the spectrum of co-occurrence of PC and AI with KRT17 gene variants, and elucidated the possible pathogenesis at the protein level, thereby laying a foundation for the genetic diagnosis and genetic counseling provided to individuals with PC.
Comprehensive analysis of molecular mechanisms underlying kidney stones: gene expression profiles and potential diagnostic markers
Authors: Aji Kaisaier , Aikebaier Aierken , Abula Asimujiang , Song Guang Lu 
Published: November 2024

BackgroundThe study aimed to investigate the molecular mechanisms underlying kidney stones by analyzing gene expression profiles. They focused on identifying differentially expressed genes (DEGs), performing gene set enrichment analysis (GSEA), weighted gene co-expression network analysis (WGCNA), functional enrichment analysis, and screening optimal feature genes using various machine learning algorithms.MethodsData from the GSE73680 dataset, comprising normal renal papillary tissues and Randall’s Plaque (RP) tissues, were downloaded from the GEO database. DEGs were identified using the limma R package, followed by GSEA and WGCNA to explore functional modules. Functional enrichment analysis was conducted using KEGG and Disease Ontology. Various machine learning algorithms were used for screening the most suitable feature genes, which were then assessed for their expression and diagnostic significance through Wilcoxon rank-sum tests and ROC curves. GSEA and correlation analysis were performed on optimal feature genes, and immune cell infiltration was assessed using the CIBERSORT algorithm.Results412 DEGs were identified, with 194 downregulated and 218 upregulated genes in kidney stone samples. GSEA revealed enriched pathways related to metabolic processes, immune response, and disease states. WGCNA identified modules correlated with kidney stones, particularly the yellow module. Functional enrichment analysis highlighted pathways involved in metabolism, immune response, and disease pathology. Through machine learning algorithms, KLK1 and MMP10 were identified as optimal feature genes, significantly upregulated in kidney stone samples, with high diagnostic value. GSEA further elucidated their biological functions and pathway associations.ConclusionThe study comprehensively analyzed gene expression profiles to uncover molecular mechanisms underlying kidney stones. KLK1 and MMP10 were identified as potential diagnostic markers and key players in kidney stone progression. Functional enrichment analysis provided insights into their roles in metabolic processes, immune response, and disease pathology. These results contribute significantly to a better understanding of kidney stone pathogenesis and may inform future diagnostic and therapeutic strategies.
Prevalence of paucibacillary cases of leprosy in Brazil: a 20-year systematic review and meta-analysis
Authors: Brito Gonçalves Bruna Eduarda , Raiol André Matheus Porto , Brito Ana Vitória Cruz , Silva Marcos Jessé Abrahão , Sardinha Daniele Melo , Lima Karla Valéria Batista , Lima Luana Nepomuceno Gondim Costa 
Published: November 2024

IntroductionLeprosy is a chronic infectious disease caused by the agent Mycobacterium leprae, characterized by its high disabling power. Data points to Brazil being the second country with the highest number of cases in the world, behind only India, representing a major challenge for public health. This work aims to determine the prevalence of paucibacillary (PB) cases in relation to leprosy cases in Brazil, using data published in the literature.MethodsThis is a systematic review and meta-analysis carried out with studies from the last 20 years, being developed based on the Preferred Reporting Items for Systematic Review and Meta-analyzes (PRISMA).The search was carried out in the databases: PUBMED, SciELO, LILACS (via VHL)and Science Direct in October 2023, using the following descriptors (((“Brazil” [Mesh]) AND (“Leprosy, paucibacillary” [Mesh])) AND “Epidemiology” [Mesh]), in English, Portuguese and Spanish. Original studies of the analytical case–control, cohort, cross-sectional, epidemiological types were selected, as well as articles with satisfactory information for numerical extraction with separate data on the paucibacillary and multibacillary clinical forms. The methodological quality assessment followed the JBI critical appraisal checklist. Statistical analysis was performed using the Comprehensive Meta-Analyses-CMA software, version 3.0 (Biostat, Engewood, NJ, United States).ResultsThe meta-analysis of the 48 studies obtained a paucibacillary prevalence rate in Brazil of 50.5% or 0.505 (95% CI = 0.502–0.509).The differences in the analyzes were statistically significant (Q-value 4302.681;df 47; I 98.905), with a high heterogeneity value evidenced by I2 (98.905). This analysis demonstrated that the frequency in the Midwest region was the highest and the South region was the lowest (21.4%). Begg’s (Kendall Tau p = 0.35) and Egger’s tests (p = 0.20) were performed, in which no high publication bias was noted. Subgroup analysis indicated that paucibacillary cases varied from region to region, with the Midwest region having the highest prevalence and the South region having the lowest.ConclusionThe results stand out significantly for the research gaps that investigate PB cases, requiring more research aimed at investigating the paucibacillary clinical form that can contribute to the early diagnosis of leprosy.Systematic review registrationPROSPERO code: CRD42024514106.