bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concise Review: Stem Cell Fate Guided By Bioactive Molecules for Tendon Regeneration
Authors: Zhang Yan-Jie , Chen Xiao , Li Gang , Chan Kai-Ming , Heng Boon Chin , Yin Zi , Ouyang Hong-Wei 
Published: March 2018

AbstractTendon disorders, which are commonly presented in the clinical setting, disrupt the patients’ normal work and life routines, and they damage the careers of athletes. However, there is still no effective treatment for tendon disorders. In the field of tissue engineering, the potential of the therapeutic application of exogenous stem cells to treat tendon pathology has been demonstrated to be promising. With the development of stem cell biology and chemical biology, strategies that use inductive tenogenic factors to program stem cell fate in situ are the most easily and readily translatable to clinical applications. In this review, we focus on bioactive molecules that can potentially induce tenogenesis in adult stem cells, and we summarize the various differentiation factors found in comparative studies. Moreover, we discuss the molecular regulatory mechanisms of tenogenesis, and we examine the various challenges in developing standardized protocols for achieving efficient and reproducible tenogenesis. Finally, we discuss and predict future directions for tendon regeneration.
Surface analytical characterization of LiNi0.8‐yMnyCo0.2O2 (0 ≤ y ≤ 0.4) compounds for lithium‐ion battery electrodes
Authors: Azmi R. , Masoumi M. , Ehrenberg H. , Trouillet V. , Bruns M. 
Published: March 2018

This study presents the quantitative chemical state elucidation of newly developed LiNi0.8‐yMnyCo0.2O2 (0 ≤ y ≤ 0.4) cathode materials for Li‐ion batteries utilizing X‐ray photoelectron spectroscopy. For reliable quantification of the chemical states of the transition metals, namely Mn, Co, and Ni, in particular, the complex peak structures consisting of significant photoelectron multiplet splitting, shake‐up satellites, and additional Auger and photoelectron peak overlaps were incorporated. The template approach that has been used enables the unambiguous elucidation of the transition metals' oxidation states; even gradual changes in the Ni2+/Ni3+ ratio depending on the Ni content in the novel LiNi0.8‐yMnyCo0.2O2 compound series can clearly be evidenced. In all cases, special care was taken with respect to air sensitivity, contamination during sample handling, and probable method‐induced sample decomposition.
Formation of Metal Nanoparticles Directly from Bulk Sources Using Ultrasound and Application to E‐Waste Upcycling
Authors: Watt John , Austin Mariah J. , Simocko Chester K. , Pete Douglas V. , Chavez Jonathan , Ammerman Lauren M. , Huber Dale L. 
Published: March 2018

AbstractA method for creating nanoparticles directly from bulk metal by applying ultrasound to the surface in the presence of a two‐part surfactant system is presented. Implosive collapse of cavitation bubbles near the bulk metal surface generates powerful microjets, leading to material ejection. This liberated material is captured and stabilized by a surfactant bilayer in the form of nanoparticles. The method is characterized in detail using gold, but is also demonstrated on other metals and alloys, and is generally applicable. It is shown that nanoparticles can be produced regardless of the bulk metal form factor, and the method is extended to an environmentally important problem, the reclamation of gold from an electronic waste stream.
Facile Ionic Liquid‐Assisted Strategy for Direct Precipitation of Eu2+‐Activated Nanophosphors under Ambient Conditions
Authors: Terraschke Huayna , Olchowka Jacob , Geringer Eugenie , Rodrigues Aline Varella , Wickleder Claudia 
Published: March 2018

AbstractThis work describes a novel ionic liquid (IL)‐assisted synthesis strategy for a direct and easy production of Eu2+‐doped nanoparticles (NPs), where ILs are also used as fluoride sources to avoid the use of elemental fluorine or toxic hydrofluoric acid. Up to now, the direct synthesis of Eu2+‐doped nanophosphors consisted of an enormous challenge, due to the oxidation to Eu3+ observed in hydrous solution, which is commonly used for the preparation of NPs, generating lattice defects and undesired particle growth or agglomeration by additional reducing steps at high temperatures. In contrast, ILs, unless containing ClO4
– or NO3
– anions, do not present an oxidizing character, allowing the direct precipitation of NPs, e.g., using Eu2+ containing starting materials. Here, the undoped and Eu2+‐doped BaFCl NPs have been prepared under atmospheric conditions for the first time using ILs as solvents and also as fluoride source, applying sonochemical and microwave‐assisted approaches. In general, this method bears an enormous potential for an easy synthesis of fluoride materials compared to inconvenient solid‐state methods. In addition, the IL plays the role of a strongly attached protecting shell which represents ≈7–8% of the total NPs weight.
Pine‐Needle‐Like Cu–Co Skeleton Composited with Li4Ti5O12 Forming Core–Branch Arrays for High‐Rate Lithium Ion Storage
Authors: Zhou Cheng‐ao , Xia Xinhui , Wang Yadong , Yao Zhujun , Wu Jianbo , Wang Xiuli , Tu Jiangping 
Published: March 2018

AbstractHigh‐performance of lithium‐ion batteries (LIBs) rely largely on the scrupulous design of nanoarchitectures and smart hybridization of bespoke active materials. In this work, the pine‐needle‐like Cu–Co skeleton is reported to support highly active Li4Ti5O12 (LTO) forming Cu–Co/LTO core–branch arrays via a united hydrothermal‐atomic layer deposition (ALD) method. ALD‐formed LTO layer is uniformly anchored on the pine‐needle‐like heterostructured Cu–Co backbone, which consists of branched Co nanowires (diameters in 20 nm) and Cu nanowires (250–300 nm) core. The designed Cu–Co/LTO core–branch arrays show combined advantages of large porosity, high electrical conductivity, and good adhesion. Due to the unique positive features, the Cu–Co/LTO electrodes are demonstrated with enhanced electrochemical performance including excellent high‐rate capacity (155 mAh g−1 at 20 C) and noticeable long‐term cycles (144 mAh g−1 at 20 C after 3000 cycles). Additionally, the full cell assembled with activated carbon positive electrode and Cu–Co/LTO negative electrode exhibits high power/energy densities (41.6 Wh kg−1 at 7.5 kW kg−1). The design protocol combining binder‐free characteristics and array configuration opens a new door for construction of advanced electrodes for application in high‐rate electrochemical energy storage.
Analysis of the changes in communication and social interactions during the transformation of a traditional team into an agile team
Authors: Espinosa‐Curiel Ismael Edrein , Rodríguez‐Jacobo Josefina , Vázquez‐Alfaro Erika , Fernández‐Zepeda José Alberto , Fajardo‐Delgado Daniel 
Published: March 2018

AbstractTraditional software teams that implement agile methodologies frequently experience difficulty working efficiently as agile teams. While agile methodologies support and promote social activities and behaviors, the understanding of the social phenomena and challenges that arise during the transformation of traditional teams into agile teams is limited. We conducted an extensive 10‐month case study in a software enterprise to analyze the changes in the communication and social interactions of employees during the transformation process, and to delineate the social challenges that arise during this process. Using social interaction registers, we collected data on the communication and social interactions of employees, first when they worked as a traditional team and then as an agile team. Then, we processed the data using social network analysis methods to identify the differences between these 2 types of teams and to create graphs of communication and social interaction networks. We identified that the transformation process influences formal, informal, oral, and written communication and increases conjunctive and disjunctive social interactions. Further, from the results of interviews conducted with all the enterprise members, we identified 5 social challenges to transforming a traditional team into an agile one. The results of this research suggest that the transformation process requires broad changes in the relationships and interactions among employees.
Perovskite Solar Absorbers: Materials by Design
Authors: Xu Qiaoling , Yang Dongwen , Lv Jian , Sun Yi‐Yang , Zhang Lijun 
Published: March 2018

AbstractSolar‐cell materials with a tetrahedral diamond structure and its derived structures (i.e., zinc blende and chalcopyrite) are the most successful family of materials, with power conversion efficiencies exceeding 20%. Recent breakthroughs based on lead halide perovskites have inspired intensive research on low‐cost photovoltaics beyond diamond‐structured materials. While research has focused on addressing the key challenges faced by lead halide perovskites, that is, the stability and toxicity issues, it is of greater interest to develop perovskites into a new family of solar‐cell materials. Here, the recent efforts toward this goal are reviewed. The focus is on computational materials design, including single, double, 2D, and nonhalide perovskites and perovskite‐like materials. Meanwhile, related experiments are also reviewed with a hope that such this will help identify potential issues as well as enlightening ideas to achieve further computation‐driven materials discovery.
Immunostimulation and Immunosuppression: Nanotechnology on the Brink
Authors: Fontana Flavia , Figueiredo Patrícia , Bauleth‐Ramos Tomás , Correia Alexandra , Santos Hélder A. 
Published: March 2018

AbstractImmunotherapy is revolutionizing current therapies in cancer and in autoimmune diseases, showing impressive results in clinical trials. Recently, the development of innovative nano‐biomaterials has been focusing on the interactions between such materials and the immune system, both in the adaptive and innate branches. Biomaterials can display immunostimulative, neutral, or immunosuppressive interactions. Nanoparticles displaying immunostimulative potential are employed in the formulation of cancer vaccines, while immunosuppressive materials are being researched for the development of vaccines able to induce tolerance in autoimmune diseases. Here, the properties influencing the immunomodulation effect of nanomaterials are analyzed, followed by a detailed review of the recent applications of nanomaterials for the delivery of antigens, adjuvants, chemotherapeutics, and immunomodulatory drugs.
The drop that makes a vase overflow: Understanding Maya society through daily water management
Authors: Ertsen Maurits W. , Wouters Kyra 
Published: March 2018

Water is an important key to understand Maya society, especially water availability within a context of climatic changes. Increasing drought would have pushed the Maya water systems into collapse. This paper studies the Maya water systems from an action‐oriented perspective, in order to understand what challenges the Maya had to overcome when dealing with water. The systems found at Tikal serve as main example, allowing comparisons with other Maya sites. In this analysis, hydraulic‐ and agent‐based elements are combined in a model to investigate the performance of the water system within extreme weather conditions and changing human agency. The results suggest that the Tikal water system was able to cope with most of the extreme situations. Furthermore, model results allow proposing that the Maya did not anticipate on short‐term changes in external conditions. Generally, in Tikal surpluses of water may have been as important as shortages of water. The extensive system of drains and canals present at Tikal may have been built to move water from the center of the city rather than to supply water to lower situated reservoirs during the dry season. Such a water‐removal system could be less centrally orientated and organized than is often argued. This could also mean that organizational structures of water systems of different city centers (Tikal, Calakmul, and Caracol) were more similar than usually assumed.This article is categorized under:Human Water > Water as Imagined and RepresentedEngineering Water > Planning WaterScience of Water > Water Quality
Hospital Teaching Status and Patients’ Outcomes After Colon Cancer Surgery
Authors: van Groningen Julia T. , Eddes Eric H. , Fabry Hans F. J. , van Tilburg Marc W. A. , van Nieuwenhoven Ernst J. , Snel Yvonne , Marang‐van de Mheen Perla J. , de Noo Mirre E. ,   Dutch Surgical Colorectal Cancer Audit Group and the Co‐operating General Hospitals
Published: March 2018

AbstractBackground and objectivesIt is increasingly accepted that quality of colon cancer surgery might be secured by combining volume standards with audit implementation. However, debate remains about other structural factors also influencing this quality, such as hospital teaching status. This study evaluates short‐term outcomes after colon cancer surgery of patients treated in general, teaching or academic hospitals.MethodsAll patients (n = 23,593) registered in the Dutch Colorectal Audit undergoing colon cancer surgery between 2011 and 2014 were included. Patients were divided into groups based on teaching status of their hospital. Main outcome measures were serious complications, failure to rescue (FTR) and 30‐day or in‐hospital mortality. Multivariate logistic regression models on these outcome measures and with hospital teaching status as primary determinant were used, adjusted for case‐mix, year of surgery and hospital volume.ResultsPatients treated in teaching and academic hospitals showed higher adjusted serious complication rates, compared to patients treated in general hospitals (odds ratio 1.25 95% CI [1.11–1.39] and OR 1.23 [1.05–1.46]). However, patients treated in teaching hospitals had lower adjusted FTR rates than patients treated in general hospitals (OR 0.63 [0.44–0.89]). However, for all outcomes there was considerable between‐hospitals variation within each type of teaching status.ConclusionOn average, patients treated in general hospitals had lower serious complication rates, but patients treated in teaching hospitals had more favorable FTR rates. Given the hospital variation within each hospital teaching type, it is possible to deliver excellent care regardless of the hospital teaching type.
Identifying Factors Underlying the Decision for Sickle Cell Carrier Screening Among African Americans Within Middle Reproductive Age
Authors: Mayo‐Gamble Tilicia L. , Middlestadt Susan E. , Lin Hsien‐Chang , Cunningham‐Erves Jennifer , Barnes Priscilla , Jackson Pamela Braboy 
Published: March 2018

AbstractGuidelines recommend that African Americans know their sickle cell trait status to inform reproductive health decisions. Few studies have applied a behavioral theory to identify factors associated with sickle cell trait screening to inform intervention targets to increase this behavior. We applied a Sickle Cell Trait Screening Framework to identify factors associated with African Americans’ intention to ask for sickle cell trait screening. Participants (N = 300), ages 18 to 35, completed a cross‐sectional survey. A three‐step sequential ordinary least squares regression analysis identified factors influencing intention. Results indicated socio‐demographic factors (age, education), knowledge and fear beliefs (screening knowledge, perceived threat), and reasoned action approach (RAA) constructs were associated with intention. RAA constructs influenced intention over knowledge and fear beliefs with an increase in R2 of .468. Perceived behavioral control was more predictive of intention (β = .576, p < .001). Attitude and perceived norm also had significant weights (β = .325 and β = .192, both p < .001, respectively). Findings from this study can inform strategies (e.g., eliminating costs associated with screening, reducing fear of painful tests) to increase sickle cell trait screening among African Americans. Ultimately, more sickle cell carriers will become aware of their trait status and be able to make informed reproductive health decisions.
Memory concerns in the early Alzheimer's disease prodrome: Regional association with tau deposition
Authors: Swinford Cecily G. , Risacher Shannon L. , Charil Arnaud , Schwarz Adam J. , Saykin Andrew J. ,   Alzheimer's Disease Neuroimaging Initiative
Published: March 2018

AbstractIntroductionRelationship between self– and informant memory concerns and tau aggregation was assessed in adults at risk for Alzheimer's disease (AD).MethodsRegional mean standardized uptake value ratios were extracted from [18F]flortaucipir positron emission tomography (PET) scans of 82 at‐risk adults in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. Associations between self– and informant ECog memory scores and tau aggregation were analyzed on both regional and voxelwise bases. Analyses were completed both on the whole sample and restricted to amyloid‐positive individuals only.ResultsMemory concerns were associated with tau aggregation. Self‐perception was more associated with frontal tau. In contrast, informant scores were more associated with parietal tau. This source‐by‐region interaction was more prominent in amyloid‐positive participants and observed in both regional and voxelwise analyses.DiscussionQuantitative assessment of perceived memory functioning may be useful for screening older adults at risk for Alzheimer's disease. Individuals and their informants may provide complementary information relating to the anatomical distribution of tau.
Luxação anterior isolada da cabeça radial com apresentação atípica em um adulto: Relato de caso
Authors: Kansay Rajeev , Gupta Sandeep , Soni Ashwani , Malhotra Anubhav , Garg Sudhir Kumar 
Published: March 2018

ResumoA literatura sobre a luxação anterior isolada da cabeça do rádio é escassa, com apenas cinco casos relatados no mundo inteiro até hoje. Em todos esses casos, os pacientes apresentaram movimentos de supinação–pronação restritos do antebraço, e manutenção da flexão–extensão do cotovelo. Os autores apresentam um caso incomum de luxação de cabeça radial anterior isolada em um paciente do sexo masculino de 18 anos, que apresentou movimentos de supinação–pronação no antebraço e restrição na flexão–extensão do cotovelo. A redução fechada foi tentada, mas sem sucesso. Assim, foi feita a redução aberta. No entanto, a redução foi instável devido à ruptura do ligamento anular. Por isso, o reparo do ligamento anular foi realizado, e um fio de Kirschner rádio-ulnar foi inserido para manter a redução da articulação rádio-ulnar proximal, evitando estresse sobre o ligamento anular, facilitando sua cicatrização. Aos 12 meses de acompanhamento, o paciente apresentava função normal do cotovelo e amplitude de movimento completa.
A case of giant cell arteritis and polymyalgia rheumatica misdiagnosed as temporomandibular dysfunction
Authors: Nys Margaux , Van der Cruyssen Fráderic , David Karel , Politis Constantinus 
Published: March 2018

AbstractWe report the case of a 83‐year‐old man who presented with bilateral scalp ulcerations, temporomandibular joint pain, anorexia, and generalized discomfort. The aspecific presentation and timing of the symptoms led to a referral delay of 117 days. A temporal artery biopsy confirmed the diagnosis of giant cell arteritis (GCA). FDG‐PET showed increased uptake at the large vessels, shoulders, and hips, suggesting concomitant polymyalgia rheumatica. Initiation of methylprednisolone resulted in resolution of the muscle‐related complaints and healing of the ulcerations. This report highlights the importance of prompt diagnosis and the rarity of bilateral scalp necrosis in GCA, with an incidence of <5%.
Masked AES PUF: a new PUF against hybrid SCA/MLAs
Authors: Yu Weize , Chen Jia 
Published: March 2018

A masked advanced encryption standard (AES) physical unclonable function (PUF) architecture is proposed for hardware authentication against hybrid side‐channel (SCA) and machine‐learning attacks (MLAs). The random mismatches of the load capacitance of the masked substitution‐boxes in the AES cryptographic circuit induced by the fabrication process are utilised for generating the critical‐authentication data against SCAs. Moreover, a mask data is added to the input challenge data to mask the actual input data of the proposed PUF against MLAs. As demonstrated in the results, the masked AES PUF proposed shows a nearly 51.1% uniformity, 50.7% inter‐Hamming distance, and 98.1% reliability. Furthermore, if a hybrid SCA/MLA is performed on the proposed PUF by combining the corresponding side‐channel leakage with the deep neural network algorithm, the prediction rate of the output responses of the masked AES PUF is only 55.2% after 100,000 number of challenge‐to‐response pairs are used for training.
Single‐channel 100 Gbit/s transmission using III–V UTC‐PDs for future IEEE 802.15.3d wireless links in the 300 GHz band
Authors: Chinni V.K. , Latzel P. , Zégaoui M. , Coinon C. , Wallart X. , Peytavit E. , Lampin J.F. , Engenhardt K. , Szriftgiser P. , Zaknoune M. , Ducournau G. 
Published: March 2018

The achievement of single‐channel 100 Gbit/s transmission, using linear unitravelling carrier photodiodes and QAM‐16 modulation format is reported. The wireless link has been done in the indoor case, considering the recent frequency standardised 300 GHz bands.
Ich würde dich so gerne verstehen!
Authors: Bär Marion 
Published: March 2018

Zusammenfassung
Hermeneutische Kompetenz in der Pflege von Menschen mit Demenz Bei der Pflege von Menschen mit Demenz kommen Pflegende immer wieder an ihre Grenzen.
Hilfreich ist, die eigene Haltung zu überprüfen und den Blickwinkel zu ändern. Unsere Autorin erläutert anhand eines Fallbeispiels, wie die Schlüsselkompetenz
„Verstehen“ trainiert werden kann und bedürfnisorientierte Pflege gelingt.
Tourism demand modelling and forecasting.
Authors: Witt S. F. , Moutinho L. , Huarng KunHuang Huarng KunHuang , Yu HuiKuang [Yu H. K. T. ] 
Published: March 2018

Abstract

This chapter examines several tourism demand forecasting methods (qualitative and quantitative) and provides examples which illustrate potential applications of the various methods. The main methods described are: Delphi and jury of executive opinion; cross-impact analysis; probability forecasting; econometric forecasting; and fuzzy time series forecasting.
Strategic thinking in tourism.
Authors: Vargas-Sánchez A. , Moutinho L. 
Published: March 2018

Abstract

This chapter introduces the nascent issue of strategic thinking in tourism. There is an initial section on the meaning of management. The chapter then delves into the changing fortunes of strategic planning as well as into the underpinnings of systems thinking. Sense and respond systems, strategic agility and value-based management are also covered. The chapter ends with the introduction of a novel concept: betapreneurship.
Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases
Authors: Watanabe Yuko , Furukawa Eri , Tatsukawa Hideki , Hashimoto Hisashi , Kamei Yasuhiro , Taniguchi Yoshihito , Hitomi Kiyotaka 
Published: March 2018

Abstract
Transglutaminase (TG) is an essential enzyme to catalyze cross-linking reactions of epidermal proteins. Recently, we biochemically characterized human skin TG orthologues for medaka (Oryzias latipes), a model fish. By genome editing, gene-modified fishes for the two orthologues were obtained, both of which lack the ordinal enzymes. These fish appeared to exhibit higher susceptibility to osmolality at the period of larvae.