bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relation between digital transformation and internationalization – a systematic literature review
Authors: Nunes Moema Pereira , Malagri Claudia Natali Alba , Steinbruch Fernanda Kalil , Schreiber Dusan , Damacena Claudio 
Published: October 2024

PurposeTo identify and analyze the relevant themes in the literature on digital transformation and internationalization, revealing opportunities for future studies.Design/methodology/approachA systematic literature review was developed using the Scopus and Web of Science databases. Initially, 156 publications were identified. Based on inclusion/exclusion criteria, a final sample of 74 articles was reached. A bibliometric and qualitative analysis were developed.FindingsEight main themes related to internationalization, such as internationalization strategy, internationalized companies, marketing-related issues, export, global supply chain, entrepreneurship and new ventures, SMEs internationalization and internationalization of educational institutions, were identified. Eight main themes related to digital transformation were also identified, including internationalization drivers, digital technologies, business model innovation, digitalization, Industry 4.0, digital platforms and e-commerce, people and digital transformation and digital institutional environment.Originality/valueIn recent years, the term digital transformation has become part of the daily lives of many organizations and of life in society itself. For internationalized companies, this discussion has also become present. Although a relationship between digital transformation and internationalization is often presented, the dimensions of analysis of this relationship are still very fragmented, and this study presents a systemic view of the themes. These themes represent opportunities for future studies.
Worldwide publications on deviance: a Web of Science evidence from 1965 to 2024
Authors: Ashraf Muhammad Umair , Ali Nusrat , Hafeez Muhammad Rashid , Hussain Siraj , Imran Muhammad 
Published: October 2024

Purpose
Deviance includes behaviors that deviate from societal norms. Scholars belonging to various disciplines have extensively studied this phenomenon. This study aims to understand the length and breadth of the deviance landscape.

Design/methodology/approach
Through a systematic analysis of publications, authors, journals and countries involved in research, this investigation unveils the inherently interdisciplinary nature of the subject. It unveils the prominent journals and influential authors who have made significant contributions to the field, shedding light on the evolving trends and shifting emphases over time.

Findings
The findings underscore the ever-growing relevance and importance of deviance research in contemporary society. They emphasize the pressing need for ongoing exploration to grapple with the intricate challenges posed by deviant behaviors.

Originality/value
This comprehensive bibliometric analysis serves as an invaluable resource, catering to the needs of researchers and practitioners with a vested interest in comprehending and advancing the study of deviance in its myriad manifestations.
Citation classics on distance and online learning: a bibliometric analysis
Authors: Sahoo Sidhartha , Pandey Shriram , Mishra Sanjaya 
Published: October 2024

Purpose
The purpose of this study is to identify seminal research works on distance and online learning that have had significant impact on the domain.

Design/methodology/approach
The authors used the SCOPUS database for this study as the data source, and a well-defined search strategy retrieved the items for analysis. First, the authors identified the h-index (n = 207) of the discipline to determine the threshold for listing the top works. The authors critically analysed these classic publications using several bibliometric parameters to present the analysis. To understand the primary focus of the classic research works, the authors also carried out a keyword cluster analysis using VOSviewer.

Findings
While the USA produced maximum classic research, authors from Canada have maximum research visibility in terms of citations (n = 474.06). Canada also received the highest value of RCI (1.30), followed by Taiwan and Australia. The majority of the classics are published in 67 scientific journals. Of these, Computers and Education published the highest number with a quarter of the total citations (n = 19,403). Although e-learning was the nucleus of the research theme, the authors observed that students, learning systems, online learning, blended learning, learning management systems and computer-aided instructions dominated their influence in the research cluster.

Originality/value
To the best of the authors’ knowledge, this is the first of its kind work in the field of distance and online learning. Findings of this study would be useful to faculty, researchers and students in the discipline to focus on the seminal works and understand their implications better in the context of the growing significance of the discipline.
Narratives of growth of formative technological innovation systems based on a knowledge perspective: the case of medical devices
Authors: Avila-Robinson Alfonso , Miyazaki Kumiko , Islam Nazrul , Sengoku Shintaro 
Published: October 2024

Purpose
This study aims to analyze the narratives of growth during the initial stages of development of the medical device technological innovation system (TIS). This paper used micro/nanofluidic-based point-of-care testing (mnPOCT), a breakthrough technology in the health-care sector.

Design/methodology/approach
This study presents a framework that includes measures of knowledge breadth and sharing mechanisms based on cognitive and actor-based networks. The framework integrates bibliometric, network and statistics-based approaches with a focus on the first decade of mnPOCT development.

Findings
In addition to the typical patterns of technological emergence, the mnPOCT sector exhibits distinctive characteristics. This paper observed significant scientific content and a high geographic concentration. Although small- and medium-sized enterprises, particularly startups, detonate knowledge development, large companies play a subtle yet impactful role as innovation mediators. Interfirm alliances are sparse, reflecting the complementarities between startups and large firms throughout the innovation value chain. These alliances show a significant correlation with SME knowledge creation.

Research limitations/implications
This study provides researchers and practitioners with guidelines for assessing the dynamics of the growth of technologies in the earliest stages of growth through knowledge and implications for research strategy toward the development and deployment of effective system interventions.

Originality/value
The study of formative TISs presents challenges because of the nascent characteristics and uncertainties surrounding emerging technologies. Current discussions on the narratives of growth of emerging TISs are limited to broad descriptions, which hinder understanding of these formative stages. This study offers a unique approach to assessing the initial stages of technological evolution. Moreover, it contributes to the existing literature by providing guidelines for managing new technologies for R&D researchers and practitioners.
Banks’ financial performance analysis: an experience from an Islamic economy
Authors: Mashayekhi Bita , Ghasemi Dashtaki Samira , Ahmadi Hossein 
Published: October 2024

Purpose
This study aims to analyze the performance efficiency of private commercial banks in Iran as an Islamic economy.

Design/methodology/approach
A meticulously chosen sample comprising 15 private banks from 2020 to 2023 has been examined. This study uses data envelopment analysis (DEA) models, specifically the Constant Returns to Scale (CCR) with input orientation and the Variable Returns to Scale (BCC) with input orientation, to scrutinize performance efficiency relative to the banking sector’s average efficiency ratio.

Findings
The findings indicate that the performance of decision making units is superior in BCC models when determined with CCR models. The CCR-I analysis spanning 2020–2023 reveals that only two banks consistently demonstrated full efficiency performance, attaining a 100% efficiency score across all years. The observed fluctuations in banks’ efficiency performance are attributed to disparities between the growth or reduction in inputs and the corresponding augmentation or diminution in outputs.

Research limitations/implications
This paper has some limitations. First, selecting inputs and outputs for the DEA models is crucial, as this study’s results are sensitive to these choices. Second, this research focused exclusively on the efficiency of private banks and did not assess the efficiency of governmental banks.

Practical implications
The insights from this study can be valuable for bank managers in evaluating performance, regulators in maintaining financial stability and investors and market analysts in enhancing their investment strategies through bank performance analysis.

Originality/value
To the best of the authors’ knowledge, this study is the first to propose a framework for evaluating and forecasting commercial bank performance in an Islamic background. This model for prediction performance would be helpful for future research on the banking sector. In addition to improving Islamic banking literature, this research contributes to the literature regarding the analysis methods usually used.
Free to have imbalance? Freelancers’ work–life balance and the moderating role of three key work facets
Authors: Flatøy Christer André 
Published: October 2024

PurposeThe purpose of this paper is to enrich the HRM literature on freelancers’ work–life balance. To do so, we investigate the difference in freelance and employed journalists’ work–life balance and the moderating role of work-scheduling autonomy, job-income security and collegial informational support, drawing on a theory novel to the HRM literature, that is, the Stress of Higher Status Theory.Design/methodology/approachData were collected with a survey questionnaire that was administered to a sample of 1,166 journalists, including 118 freelancers, in Norway in 2021. We analysed this data using a stepwise regression analysis.FindingsWe report three main findings: First, we find evidence indicating that freelance journalists have less work–life balance than employed journalists. Second, our results provide support for the Stress of Higher Status Theory and testify to the relevance this theory has for high-skill workers. Third, only collegial support significantly (positively) moderates freelancers’ work–life balance.Originality/valueThis study adds to the existing literature on freelancing and work–life balance, demonstrating that individuals’ work arrangements have the potential to shape their work facets and work–life balance. The theoretical and practical implications of this are discussed.
Review of the fluoropyrimidine antidote uridine triacetate
Authors: Thompson Jack T. , Wood David M. , Dargan Paul I. 
Published: October 2024

AbstractIn 2015, the United States Food and Drug Administration (FDA) approved uridine triacetate to treat overdose and severe toxicity of the fluoropyrimidine chemotherapy agents 5‐fluorouracil (5‐FU) and its oral prodrug capecitabine. Uridine triacetate is as an oral prodrug of uridine that competes with cytotoxic fluoropyrimidine metabolites for incorporation into nucleotides. Two million people worldwide start fluoropyrimidine chemotherapy each year, with 20‐30% developing severe or life‐threatening adverse effects, often attributable to a genetic predisposition such as dihydropyrimidine dehydrogenase deficiency. Whilst genetic prescreening is recommended prior to starting fluoropyrimidine agents, this only prevents 20‐30% of early‐onset life‐threatening toxicity and so does not obviate the need for an antidote. Initial in‐human studies established that uridine triacetate more than doubles the maximum tolerated weekly 5‐FU bolus dose. A lack of clinical equipoise meant a placebo‐controlled phase III trial was not ethical and so the phase III trials used historical controls. These found that uridine triacetate improved survival in those with fluoropyrimidine overdose and severe toxicity from 16% to 94%, with 34% able to resume chemotherapy within 30 days. Five case reports of delayed fluoropyrimidine toxicity demonstrate improvement following uridine triacetate treatment 120‐504 h after last fluoropyrimidine administration, suggesting efficacy beyond the FDA licencing indications. Mechanistically uridine triacetate would be expected to be effective for overdose and severe toxicity of tegafur (a 5‐FU prodrug), but there are no published case reports describing this. Uridine triacetate is available internationally through an expanded access scheme and has been available in the UK since 2019 on a named patient basis.
Effects of age, sex, daily dose, comorbidity and co‐medication on venlafaxine‐associated cardiovascular adverse events: A pharmacovigilance analysis of the FDA Adverse Event Reporting System database
Authors: Wang Zhanzhang , Lu Haoyang , Li Yuandan , Huang Shanqing , Zhang Ming , Wen Yuguan , Shang Dewei 
Published: October 2024

AbstractAimsThis study aimed to provide a comprehensive view of cardiovascular adverse events (AEs) associated with venlafaxine (VEN) therapy.MethodsCardiovascular AE reports for patients receiving VEN therapy were retrieved from January 2004 to December 2023 from the FDA Adverse Event Reporting System database. Effects of age, sex and daily VEN dose on the occurrence of different types of cardiovascular AEs and the influence of demographics, VEN dose, comorbidity and co‐medication on death in patients with cardiovascular AEs were analysed by multivariate logistic regression analysis.ResultsThe study included 16 110 AE reports following VEN treatment (median age: 51 years, females: 69.78%, median VEN daily dose: 100 mg/day). VEN daily dose was associated with increased risks of cardiac arrhythmias, embolic and thrombotic events, torsade de pointes/QT prolongation, ischaemic heart disease, cardiac failure, cardiomyopathy and overall cardiovascular events. The elderly (≥ 75 years), male sex, comorbidity (infections and infestations, cardiac disorders, nervous system disorders) and co‐medication (quetiapine and clozapine) were related to death following VEN‐associated cardiovascular AEs; however, the risk of cardiovascular death did not increase with regular VEN doses.ConclusionsOur study confirmed the association of cardiovascular AEs with VEN therapy and revealed the influencing factors for the risk of VEN‐related cardiovascular AEs and death due to these events. Based on the obtained evidence, the cardiovascular health of late‐elderly patients with complex comorbidity and polytherapy should be closely monitored when they receive VEN therapy. As an exploratory study, prospective studies are needed to validate our findings in the future.
Trauma and social pathways to psychosis: Examining the role of attachment, social rank and dissociation in a clinical sample
Authors: Grady Shelley , Crowley Niall , Scott Seamus , Ndukwe Charles Ifegwu , Donohoe Rebecca , Gaynor Keith 
Published: October 2024

AbstractObjectivesThe trauma and social pathways model of psychosis proposes interactions between trauma, attachment, social rank and dissociation in pathways to psychosis, though this model has yet to be empirically investigated. The primary aim of this study was to examine the overall predictive value of the trauma and social pathways model using regression analysis. A secondary aim was to delineate hypothesized pathways between trauma and positive symptoms of psychosis using serial mediation analysis.MethodThis was a cross‐sectional study of people attending mental health services for a psychosis‐related diagnosis (N = 71). Measures of trauma, positive symptoms of psychosis, attachment, social comparison and dissociation were completed.ResultsA model of recurrent trauma, insecure attachment, social rank and dissociation predicted 23.2% of the variance in positive symptoms of psychosis. Recurrent trauma, attachment and dissociation contributed significantly to the model, while social rank did not. Further, serial mediation analysis indicated that the sequence of disorganized attachment and dissociation fully mediated the relationship between recurrent trauma and positive symptoms.ConclusionsResults provide preliminary support for the trauma and social pathways model of psychosis, specifically as it relates to recurrent trauma, insecure attachment and dissociation. Results did not support the social rank component of this model, however. These findings provide clear targets for the development of next‐wave psychological interventions that focus on trauma‐related variables in psychosis. Future studies should replicate these findings with a larger clinical sample, and consider a measure of shame to further elucidate social processes in pathways to psychosis.
The Association Between Latino Cultural Concepts and Fatherhood Identity on Stigma for Fathers With a Child With a Disability
Authors: Mogro‐Wilson Cristina , Longo Emily , Loomis Alysse , Rose Devon Musson 
Published: October 2024

ABSTRACTThis study focuses on Latino fathers and investigates the role that cultural concepts and fatherhood identity play in the stigma associated with having a child with a disability. Disability stigma is a widely held concept that acknowledges the role of culture; however, there is a lack of information on Latino fathers. Using a panel survey provider a US cross‐sectional survey was completed by 92 Latino fathers who had a child with a disability. Multiple regression was used to investigate the relationship of cultural Latino constructs (personalismo, machismo, caballerismo and respeto) and fatherhood identity on the stigma experiences of Latino fathers who have a child with a disability while controlling for the child's age and acculturation (R2 = 0.43, p < 0.001). Latino fathers with higher levels of personalismo (p = 0.05), and fatherhood identity (p < 0.001) had lower levels of stigma. Latino fathers with high levels of machismo had high levels of stigma (p < 0.001). There was no significant relationship between caballerismo and respeto towards stigma. Specific recommendations for Latino fathers include (1) the development of personalismo by focusing on the child–parent relationship; (2) a re‐frame of machismo to focus instead on caballerismo characteristics to de‐emphasize harmful effects on stigma experiences; and (3) heightening the identity as a father as a protective mechanism to strengthen resilience from stigma.
Role of Hippocampal Glutamatergic Synaptic Alterations in Sevoflurane‐Induced Cognitive Dysfunction in Aged Mice
Authors: Niu Yixuan , Liao Guoying , Miao Zhengjie , Xu Jinnan , Cheng Yanyong , Wang Fan , Qi Chuanyu , Chen Tiannan , Gao Yi , Zhang Lei , Jiang Hong , Yan Jia 
Published: October 2024

ABSTRACTAimsPerioperative neurocognitive disorders (PND), including postoperative delirium (POD) and postoperative cognitive dysfunction (POCD), are common following anesthesia and surgery in older patients and significantly increase morbidity and mortality. However, the underlying mechanism of PND is unclear. Our study aims to analyze the differentially expressed genes (DEGs) in excitatory neurons and investigate the role of hippocampal glutamatergic synaptic alterations in sevoflurane‐induced cognitive dysfunction in aged mice.MethodsWe performed single‐nucleus RNA sequencing (snRNA‐seq) technology to examine the alterations of excitatory neurons in hippocampus induced by sevoflurane in aged mice. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of DEGs were performed in excitatory neurons. At last, immunofluorescence staining was used to validate sevoflurane‐induced alternation of glutamatergic synapses in the hippocampus of aged mice.ResultsThis study demonstrates that DEGs in excitatory neurons are associated with reduction of glutamatergic synapses and cognitive dysfunction. After immunofluorescence staining validation, we also confirmed that sevoflurane anesthesia decreased the density of glutamatergic synapses in the hippocampus of aged mice.ConclusionsOur findings demonstrated a key role of hippocampal glutamatergic synaptic alterations in sevoflurane‐induced cognitive dysfunction in aged mice.
Knockdown of tyrosine hydroxylase gene affects larval survival, pupation and adult eclosion in Plagiodera versicolora
Authors: Liu Xiaolong , Wang Xin , Zhang Qi , Ze Longji , Zhang Hainan , Lu Min 
Published: October 2024

AbstractIn insects, tyrosine hydroxylase (TH) plays essential roles in cuticle tanning and cuticle pigmentation. Plagiodera versicolora (Coleoptera: Chrysomelidae) is a leaf‐eating forest pest in salicaceous trees worldwide. However, the function of PverTH in P. versicolora is still unknown. In this study, we obtained a PverTH gene from transcriptome analysis. The expression analysis of PverTH showed that the highest expression was found in epidermis of larvae. In this study, we used RNA interference (RNAi) technology to knockdown the PverTH gene. The results showed that ingestion of dsTH led to cuticle coloration became lighter in larvae, pupae and adults. Knockdown of PverTH gene inhibited larval growth, and consequently caused higher mortality. In addition, RNAi of TH disrupted the cuticle tanning, caused lower pupation rate, lower eclosion rate and higher deformity rate. This study indicates that PverTH is vital for the cuticular pigments and cuticle tanning. Moreover, this research suggested that the development of PverTH gene as a potential target gene to control P. versicolora.
An Exploratory Study on the Suicidal Behaviours of People With Intellectual Disability or Autism: Examining Their Understanding of Suicide and Death, and the Perceptions of Their Direct Support Staff
Authors: Persechino Sarrah Thomas , Morin Diane , Bardon Cécile 
Published: October 2024

ABSTRACTBackgroundIndividuals with intellectual disability or autism exhibit suicidal behaviours at an equal or greater rate than the general population, yet little is known about associated risk factors. This study explores suicidality in these populations, focusing on their understanding of suicide and death and perceptions of their direct support staff regarding their suicidality.MethodSemi‐structured interviews from 23 suicidal and non‐suicidal participants and their support staff were analysed qualitatively to extract common themes and compare between groups.ResultsA breadth of suicidal behaviours was documented. Generally, suicidal participants demonstrated a more elaborate understanding of suicide and death than non‐suicidal participants. While staff often acknowledged never having discussed the topic with their client, most assumed they understood death accurately.ConclusionResults suggest interactions between conceptions of death and suicidal behaviour and a need for discussion around death and suicide in clinical settings. Implications for future research and clinical practice are discussed.