bluuebunny/crossref_metadata_2025_split huggingface dataset:
International multicentre validation of the arteriovenous malformation-related intracerebral haemorrhage (AVICH) score
Authors: Neidert Marian C. , Lawton Michael T. , Kim Louis J. , Nerva John D. , Kurisu Kaoru , Ikawa Fusao , Konczalla Juergen , Dinc Nazife , Seifert Volker , Habdank-Kolaczkowski Julian , Hatano Taketo , Hayase Makoto , Podlesek Dino , Schackert Gabriele , Wanet Thomas , Gläsker Sven , Griessenauer Christoph J. , Ogilvy Christopher S. , Kneist Andreas , Sure Ulrich , Seifert Burkhardt , Regli Luca , Bozinov Oliver , Burkhardt Jan-Karl 
Published: October 2018

ObjectiveThe recently published arteriovenous malformation-related intracerebral haemorrhage (AVICH) score showed better outcome prediction for patients with arteriovenous malformation (AVM)-related intracerebral haemorrhage (ICH) than other AVM or ICH scores. Here we present the results of a multicentre, external validation of the AVICH score.MethodsAll participating centres (n=11) provided anonymous data on 325 patients to form the Spetzler-Martin (SM) grade, the supplemented SM (sSM) grade, the ICH score and the AVICH score. Modified Rankin score (mRS) at last follow-up (mean 25.6 months) was dichotomized into favourable (mRS 0-2, n=210) and unfavourable (mRS 3-6;n=115). Univariate and AUROC analyses were performed to validate the AVICH score.ResultsExcept nidus structure and AVM size, all single parameters forming the SM, sSM, ICH and AVICH score and the scores itself were significantly different between both outcome groups in the univariate analysis. The AVICH score was confirmed to be the highest predictive outcome score with an AUROC of 0.765 compared with 0.705 for the ICH score and 0.682 for the sSM grade.ConclusionThe multicentre-validated AVICH score predicts clinical outcome superior to pre-existing scores. We suggest the routine use of this score for future clinical outcome prediction and in clinical research.Trial registration numberNCT02920645.
Higher order, multifeatural object encoding by the oculomotor system
Authors: Kehoe Devin H. , Aybulut Selvi , Fallah Mazyar 
Published: October 2018

Previous behavioral and physiological research has demonstrated that as the behavioral relevance of potential saccade goals increases, they elicit more competition during target selection processing as evidenced by increased saccade curvature and neural activity. However, these effects have only been demonstrated for lower order feature singletons, and it remains unclear whether more complicated featural differences between higher order objects also elicit vector modulation. Therefore, we measured human saccades curvature elicited by distractors bilaterally flanking a target during a visual search saccade task and systematically varied subsets of features shared between the two distractors and the target, referred to as objective similarity (OS). Our results demonstrate that saccades deviated away from the distractor highest in OS to the target and that there was a linear relationship between the magnitude of saccade deviation and the number of feature differences between the most similar distractor and the target. Furthermore, an analysis of curvature over the time course of the saccade demonstrated that curvature only occurred in the first 20–30 ms of the movement. Given the multifeatural complexity of the novel stimuli, these results suggest that saccadic target selection processing involves dynamically reweighting vector representations for movement planning to several possible targets based on their behavioral relevance. NEW & NOTEWORTHY We demonstrate that small featural differences between unfamiliar, higher order object representations modulate vector weights during saccadic target selection processing. Such effects have previously only been demonstrated for familiar, simple feature singletons (e.g., color) in which features characterize entire objects. The complexity and novelty of our stimuli suggest that the oculomotor system dynamically receives visual/cognitive information processed in the higher order representational networks of the cortical visual processing hierarchy and integrates this information for saccadic movement planning.
Multichannel Works for Nonstationary Audiences
Authors: Moeller John D. 
Published: October 2018

Abstract
There is interest in our era in the topic of sound spatialization, as evidenced by the writings, compositions, and facilities dedicated to the practice. One frequently expressed goal is to elevate space in importance as a compositional parameter. There are many approaches that make this possible, one of which is to create multichannel compositions for listeners who move physically through the presentation space. This article is an examination of such works. This article will discuss several elements in relation to navigable sonic creations using a variety of case studies, including my 96-channel piece for mobile audiences, First Vision.
Ein “Ocean von Gelehrsamkeit”
Authors: Weiß Alexander 
Published: October 2018

Abstract
The State Library Berlin and the University Library Heidelberg hold a number of letters which Adolf von Harnack received from the Scottish classicist Sir William Mitchell Ramsay. The correspondence between these two outstanding scholars is of great importance for the history of the disciplines concerned, Classics and History of the Early Church, as well as for the biographies of the two correspondents. In this article Ramsay’s letters are edited with introduction and commentary.
Seeing the Empire Through Lists and Charts: French Colonial Records in the Eighteenth Century
Authors: Houllemare Marie 
Published: October 2018

Abstract
By looking at list-making and comparative assessments of trade, this article on central administrative practices of record management aims at discussing the mobilization of archives in French colonial supervision in the eighteenth century. A Bureau des Colonies was created in the French Secretariat of the Marine in 1710: from the very outset, its main mission was to deal with the colonial records, mostly correspondence, through which the colonies were administered. Archives had been collected and classified in the Bureau des archives from 1699 onwards. But this implied an effort in the organization of papers: throughout the eighteenth century, the imperial administration created several other documentary tools that produced a simplified and ideal vision of the empire and of its place in the global order. Looking at the kinds of papers produced by the colonial administration and where these records were kept provides insight into how the central authorities understood the colonial empire. The paperwork shaped the way administrators understood empire, through operations carried out by the clerks on the records. Records were collected from all the colonies and actors, with a growing sense of being a unique agency possessing relevant records that were reduced to similar storage units by agents without field experience. In fact, archives became crucial in strengthening the empire as a political unity, under a centralized metropolitan direction, mainly after the Seven Years’ War.
The Adagia as an Institutio Principis
Authors: Gordeziani Lika 
Published: October 2018

Abstract
One of the most important topics in the complex didactic work of Erasmus, Adagia, is the question of good government. In this collection of proverbs, Erasmus uses ancient wisdom to establish some crucial principles of political education. He discusses different cases of good and bad rulers and proposes some instructions for his readers. It is not enough to properly instruct a prince; the society he governs must first be instructed. Thus, the Adages serve not only as an institutio principis, but also as a sort of institutio populi.
The Paradoxical Role of the Shanson in Putin’s Russia
Authors: Gordiienko Anastasiia 
Published: October 2018

This study analyzes the colorful phenomenon of the Russian shanson in the context of contemporary Russian culture and politics. It targets shanson’s complex symbiotic relationship with Putin’s regime and its paradoxical place within Russian culture and politics today.
The musical genre has undergone a veritable sea change over time, evolving from a subcultural form mocking official powers to a “normalized” cultural product that now bears the Kremlin’s stamp of approval. Faced with the new post-Soviet economic reality, the underworld song underwent changes that transformed it into a commercially successful genre currently acknowledged, and even deployed, by the Russian authorities. While such shifts often mark a subculture’s lifecycle, what is particularly striking in this case is the shanson’s continued bond with the underworld. Such a paradox, I contend, may be illuminated, if only in part, by the specific nature of Putin’s cultivated public persona and particular features of the Putin regime.
The polyphasic approach revealed new species of Chloroidium (Trebouxiophyceae, Chlorophyta)
Authors: DARIENKO TATYANA , LUKEŠOVÁ ALENA , PRÖSCHOLD THOMAS 
Published: October 2018

Chlorella-like coccoid green algae are widely distributed in many types of habitats such as freshwater, terrestrial and marine. One group of terrestrial microalgae belonging to the Trebouxiophyceae forms the monophyletic lineage of the Watanabea clade. This clade exclusively comprises of ellipsoid and spherical coccoid green algae, which traditionally have been assigned as different species of Chlorella. Within this clade, seven out of ten genera are described mainly based on phylogenetic analyses of SSU and rbcL sequences. Most of the genera are represented by only one or two species that are rarely found in natural samples. In contrast, the genus Chloroidium is widely distributed across different habitats. We investigated 34 new isolates, which were originally assigned as Chloroidium or Chlorella, using an integrative approach. The phylogenetic analyses of SSU and ITS rDNA sequences revealed nine lineages, eight of which were highly supported in all of our bootstrap and Bayesian analyses. The ITS-2/CBC approach clearly demonstrated that these nine lineages represent individual species. The haplotype network analyses revealed that three out of them were widely distributed and showed no preference for any habitat. The comprehensive study of SSU and rbcL datasets also revealed that no clear synapomorphy could be found to support the assigned genus Parachloroidium. As a result of our findings, we proposed that both species belonging to Parachloroidium be transferred to Chloroidium. In addition, we re-established two species originally described by Chodat as new members of Chloroidium (C. lichenum, C. viscosum). Two of the nine lineages (C. antarcticum, C. arboriculum) were newly described in this study.
Crime Prevention and the Coproduction of Security: Outcomes of Citizen Participation at the Neighborhood Level in Neoliberal Chile
Authors: Trebilcock Maria Paz , Luneke Alejandra 
Published: October 2018

A study of the implications of the coproduction-of-security policy implemented by Chile’s postdictatorship governments shows that the appeal for citizen participation in security provision has resulted in individual practices of home defense and protection rather than the development of the associative programs promoted by the state. This has come about in a context of extreme fear of crime and mistrust of the institutions in charge of security. The fact that the discourse of security coproduction is interwoven with the individuation and privatization that characterize Chilean society calls for a review of the agenda of citizen participation in security issues. Un estudio de las implicaciones de la política de coproducción de seguridad implementada por los gobiernos postdictadura de Chile muestra que el llamado a la participación ciudadana en provisión de seguridad ha resultado en prácticas individuales de defensa y protección del hogar más que en el desarrollo de programas asociativos promovidos por el estado. Esto ha ocurrido en un contexto de miedo extremo al crimen y desconfianza de las instituciones a cargo de la seguridad. El hecho de que el discurso de la coproducción de seguridad esté entrelazado con la individuación y la privatización que caracteriza a la sociedad chilena requiere una revisión de la agenda de participación ciudadana en temas de seguridad.
New daily persistent headache (NDPH) triggered by a single Valsalva event: A case series
Authors: Rozen Todd D 
Published: October 2018

Objective To describe a new subtype of new daily persistent headache that is triggered by a single Valsalva event. Methods A case series of patients was evaluated in an academic headache clinic over a 3-year time period. Results A total of seven patients (four female and three male) were diagnosed with this new subtype of new daily persistent headache. The headaches all began after a single Valsalva event. Average age at time of headache onset was 41 years (males: 39 years; females: 43 years) with an age range of 20–62 years. All patients developed their syndrome during the months of September to February with November and February being the most cited months (5/7 patients). Immediate worsening in the Trendelenburg position occurred in all patients and appeared to be an almost diagnostic test for the syndrome. No patient had papilledema on funduscopic exam. Five out of seven patients had no prior headache history including cough, exercise or migraine. Four of seven patients were of normal weight, while one was overweight and two were obese. A crowded posterior fossa was identified in five of seven patients on brain MRI. On cerebrospinal fluid pressure/volume lowering medication (acetazolamide, indomethacin and/or spironolactone), five out of seven patients achieved 90% plus improvement in headache frequency while three patients became pain free. Three patients were able to taper off medication without headache recurrence. Conclusion New daily persistent headache after a single Valsalva event appears to be a unique subtype of new daily persistent headache that is responsive to cerebrospinal fluid pressure/volume lowering medications. An abnormal reset of cerebrospinal fluid pressure/intracranial pressure to an elevated state is the presumed pathogenesis and may relate to the patient's baseline neuroanatomy of a crowded posterior fossa. There appears to be a circadian periodicity to the onset of the syndrome. Worsening in the Trendelenburg position is a probable diagnostic test. Defining new daily persistent headache subtypes by triggering event appears to be making a positive inroad in the understanding of this condition and helps present new effective therapies.
How Low-Income Smokers in New York Access Cheaper Cigarettes
Authors: Curry Laurel , Schmitt Carol L. , Henes Amy , Ortega-Peluso Christina , Battles Haven 
Published: October 2018

Purpose: To understand the tobacco acquisition practices of low-income smokers in New York State in light of high cigarette prices due to high cigarette taxes. Design: Eight focus groups with low-income smokers were conducted in spring 2015 and 2016 (n = 74). Setting: New York City (NYC) and Buffalo, New York. Participants: Low-income adults aged 18 to 65 who smoke cigarettes regularly. Method: Qualitative analysis of focus group transcripts that explored differences and similarities by region. We used the interview guide—which covered the process of acquiring cigarettes and the impact of cigarette prices—as a framework for analysis to generate themes and subthemes (deductive coding). We also generated themes and subthemes that emerged during focus group discussions (inductive coding). Results: Some smokers in Western New York have switched to untaxed cigarettes from Native American reservations, whereas low-income smokers in NYC described convenient sources of bootlegged cigarettes (packs or loosies) in their local neighborhood stores, through acquaintances, or on the street. Familiarity with the retailer was key to accessing bootlegged cigarettes from retailers. Conclusions: Smokers in this study could access cheaper cigarettes, which discouraged quit attempts and allowed them to continue smoking. The availability of lower priced cigarettes may attenuate public health efforts aimed at reducing smoking prevalence through price and tax increases.
GATA3 rs3824662 gene polymorphism as possible risk factor for systemic lupus erythematosus
Authors: Mosaad Y M , Hammad A , Elghzaly A A , Tawhid Z M E , Hammad E M , Showma A , Abdelsalam R , Elmoughy A , Fawzy I M , Anber N 
Published: October 2018

Background There is no report about the association between GATA3 rs3824662 polymorphism and systemic lupus erythematosus (SLE). Objective To investigate the possible role of GATA3 rs3824662 polymorphism as a susceptibility risk factor for either adult SLE (aSLE) or pediatric SLE (pSLE) and to evaluate its role in the development of lupus nephritis (LN) in pSLE. Methods Typing of GATA3 rs3824662 polymorphism was done using real-time polymerase chain reaction for three groups; 104 pSLE patients, 140 aSLE patients and 436 age- and sex-matched healthy controls. Results Non-significant differences were found between SLE patients and healthy controls for the allele and genotype frequencies of GATA3 rs3824662 ( p > 0.05). In pSLE; the AC genotype was associated with LN ( p = 0.04); the A allele and AC genotype were associated with persistent proteinuria ( p = 0.036 and 0.01, respectively) and both the A allele and AA genotype were associated with higher chronicity index ( p = 0.031 and 0.04, respectively). In aSLE; the C allele was associated with cellular cast ( p = 0.03) and thrombocytopenia ( p = 0.01). Logistic regression analysis revealed significant association between the AC+AA genotypes and the prediction of LN and renal active disease in pSLE ( p = 0.04 and 0.01, respectively). Conclusion GATA3 rs3824662 is not associated with susceptibility to SLE either in adult or in pediatric patients; however, in pSLE patients, the heterozygous AC genotype could be considered a risk factor for LN. At the same time, the AC and AA genotypes could be considered as predictors for LN and active renal disease. However, the small sample size is a limiting factor of the present study when interpreting the positive association.
Implementation and evaluation of Stanford Health Care store-and-forward teledermatology consultation workflow built within an existing electronic health record system
Authors: Kim Grace E , Afanasiev Olga K , O’Dell Chris , Sharp Christopher , Ko Justin M 
Published: October 2018

Introduction Teledermatology services that function separately from patients’ primary electronic health record (EHR) can lead to fragmented care, poor provider communication, privacy concerns and billing challenges. This study addresses these challenges by developing PhotoCareMD, a store-and-forward (SAF) teledermatology consultation workflow built entirely within an existing Epic-based EHR. Methods Thirty-six primary care physicians (PCPs) from eight outpatient clinics submitted 215 electronic consults (eConsults) for 211 patients to a Stanford Health Care dermatologist via PhotoCareMD. Comparisons were made with in-person referrals for this same dermatologist prior to initiation of PhotoCareMD. Results Compared to traditional in-person dermatology clinic visits, eConsults decreased the time to diagnosis and treatment from 23 days to 16 hours. The majority (73%) of eConsults were resolved electronically. In-person referrals from PhotoCareMD (27%) had a 50% lower cancellation rate compared with traditional referrals (11% versus 22%). The average in-person visit and documentation was 25 minutes compared with 8 minutes for an eConsult. PhotoCareMD saved 13 additional clinic hours to be made available to the dermatologist over the course of the pilot. At four patients per hour, this opens 52 dermatology clinic slots. Over 96% of patients had a favourable experience and 95% felt this service saved them time. Among PCPs, 100% would recommend PhotoCareMD to their colleagues and 95% said PhotoCareMD was a helpful educational tool. Discussion An internal SAF teledermatology workflow can be effectively implemented to increase access to and quality of dermatologic care. Our workflow can serve as a successful model for other hospitals and specialties.
Glial fibrillary acidic protein for the early diagnosis of intracerebral hemorrhage: Systematic review and meta-analysis of diagnostic test accuracy
Authors: Perry Luke A , Lucarelli Tom , Penny-Dimri Jahan C , McInnes Matthew DF , Mondello Stefania , Bustamante Alejandro , Montaner Joan , Foerch Christian , Kwan Patrick , Davis Stephen , Yan Bernard 
Published: October 2018

Background and aims Glial fibrillary acidic protein (GFAP) has shown promise in several studies for its ability to diagnose intracerebral hemorrhage (ICH). We evaluated the diagnostic accuracy of blood GFAP level to differentiate (ICH) from acute ischemic stroke (AIS) and stroke mimics, both overall, and in the first three hours after symptom onset. Methods We searched multiple databases, without language restriction, from inception until December 2017. Hierarchical summary receiver operating characteristic (HSROC) modeling was used to meta-analyze results. We conducted subgroup analyses restricted to blood samples collected within 0–60, 60–120, and 120–180 min time groups after symptom onset, to evaluate diagnostic accuracy in the early pre-hospital phase. Between and within study heterogeneity was explored using meta-regression. Results The search identified 199 potentially relevant citations from which 11 studies involving 1297 participants (350 ICH, 947 AIS, or mimic) were included. The pooled sensitivity, specificity, and area under the HSROC curve were 0.756 (95% CI 0.630–0.849), 0.945 (95% CI 0.858–0.980), and 0.904 (95% CI 0.878–0.931), respectively. Differences in assays used, but not the other covariates, partially explained between-study heterogeneity ( p = 0.034). The summary estimates for the 0–60, 60–120, and 120–180 min subgroups were comparable to the primary analysis and there was no statistically significant difference in diagnostic accuracy between subgroups. Conclusions GFAP is a promising diagnostic biomarker for ICH diagnosis in the early pre-hospital phase. Test accuracy is affected by assay subtype, but there are still unexplained sources of heterogeneity. High quality, international multi-center trials are warranted to develop and validate a point-of-care GFAP assay for the rapid triage and evaluation of acute stroke in the pre-hospital setting.
Calcified brain metastatic adenocarcinoma: A case report and review of the literature
Authors: Bahrami Eshagh , Taheri Morteza , Benam Mohsen 
Published: October 2018

Introduction Calcification in brain metastasis occurs rarely so it is reported in approximately 1% of surgical and 6.6% of autopsy specimens. Here we report a new case of brain metastasis with calcification. Case presentation A 44-year-old woman presented with a generalized tonic–clonic seizure with no neurological deficit on physical examination. Brain imaging demonstrated a hyperdense lesion on computed tomography scan and hyposignal and rim enhancement on T1, T2 and T1 with gadolinium injection sequence images in the right parieto-occipital lobe. Intraoperatively, there was a well-defined solid homogenous calcified mass within brain parenchyma. The lesion that resembled a meningioma was totally resected. The histopathological examination revealed metastatic adenocarcinoma. Conclusion Metastatic brain lesions should be in the differential diagnosis of a solitary calcified brain mass, although it occurs rarely. It is important to differentiate it radiologically from intralesional haemorrhage.