bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of a UV spectrophotometric method for simultaneous estimation of teneligliptin hydrobromide hydrate and pioglitazone hydrochloride in pharmaceutical dosage form
Authors: Gupta Ravi Shankar , Tiwari Akhilesh , Patel Sanjeev Kumar , Karthikeyan Chandrabose , Gupta Deepak Kumar , Soni Pranay , Joshi Megha 
Published: November 2024

Abstract
Background
This study presents the development and validation of a UV spectrophotometric method for the simultaneous estimation of teneligliptin hydrobromide hydrate (TEN) and pioglitazone hydrochloride (PIO) in pharmaceutical dosage forms. The method measures absorbance at 243 nm for TEN and 265 nm for PIO. Validation was conducted according to ICH guidelines, covering specificity, linearity, range, precision, accuracy, limit of detection, limit of quantification, and robustness.

Results
The method exhibited linearity in the 2–25 µg/ml concentration range for both TEN and PIO, with correlation coefficients close to 1. Precision studies showed low % RSD values, indicating excellent repeatability and minimal intra- and inter-day variability. Accuracy was confirmed through recovery studies, with results within the 98–102% range. The method demonstrated sensitivity with low LOD and LOQ values. Robustness testing showed stability and consistency under varying conditions. Analysis of tablet formulations confirmed the accurate quantification of both drugs.

Conclusion
The developed UV spectrophotometric method offers a simple, sensitive, and cost-effective solution for the simultaneous estimation of TEN and PIO in pharmaceutical formulations. It is suitable for routine analysis and quality assessment of tablet dosage forms.
THE DOCTRINE OF THE VIRGIN BIRTH IN CHRISTIANITY FROM THE PERSPECTIVE OF COMPARATIVE RELIGION: APPROACHES AND INTERPRETATIONS
Authors: Sobolev Yuri V. 
Published: November 2024

The article offers an examination of the doctrine of the virgin birth in Christianity within the framework of intra-confessional discussion. Paying attention to the emphasis of the doctrine of the virgin birth in the modern Protestant tradition, the question of the place and significance of the doctrine of the virgin birth in the church tradition (Orthodox and Catholic) is introduced into the problem field of the study. Separately, the question of the possibility of the new birth in an age of “the waning of faith” is raised. The interdisciplinary approach in the study allows us to identify a number of important provisions that determine the difference and commonality in the interpretations of the two traditions: the authority of holy theological exegesis, the significance and place of the oral tradition in modern Protestant communities, the primary and secondary in the understanding of the hierophanic, the rational and mystical in the spiritual experience of the believing Christian. The works of such scholars and researchers as: M. Weber, D. Melton, M. Eliade, M. Foucault, L. Harrison, D. Bogolepov, S. Horuzhiy, I. Yablokov. An important place in the study of the issue is occupied by the holy theological heritage - the works of John Chrysostom and Simeon the New Theologian. As methods of research were used: the method of comparative religious studies, hermeneutic-textual analysis, socio-historical and cultural approaches. In the course of the work, a number of important conclusions have been drawn about the understanding and place of the doctrine of the virgin birth in Christian doctrine. The most important of which are: the significance of explicitness and understanding of the virgin birth in Protestantism; the complexity and implicitness of the Church's exegesis of the virgin birth, expressed in two main vectors of understanding of this question. These articles can be used in the research activities of philosophers-religionists on the history of Christianity. The practical value of the study lies in the possibility of incorporating the results into classes in philosophy, religious studies and theology, as well as directly in missionary activities.
Geoestrategias de paz y espacios de desenzarzamiento: diferentes procesos, diferentes espacios, a diferentes escalas y con diferentes calendarios
Authors: Cairo Carou Heriberto 
Published: November 2024

La paz se construye en lugares específicos, que no son intercambiables, a través de prácticas espaciales definidas que construyen estructuras espaciales a diferentes escalas. Existe una gran cantidad de literatura sobre los procesos utilizados para construir la paz —el cómo de la construcción de la paz—; sin embargo, hay poca investigación que examine la cuestión de dónde ocurren la paz y la consolidación de la paz. Las zonas libres de armas nucleares (ZLAN) y las zonas de paz regionales (ZdeP) —y también las ZdeP locales— son espacios delimitados. Es decir, tienen un carácter principalmente territorial, aunque no en los habituales términos militaristas, porque todas ellas son iniciativas de desarme, por lo que son formas alternativas de entender la defensa. Las ZLAN son un concepto relacionado con la política de seguridad, de hecho, es una política de seguridad alternativa. En efecto, si entendemos el territorio como tecnología política, las zlan y las ZdeP son tecnologías olíticas pacifistas, que destacan entre las que se proponen en este trabajo.
Staggered Health Policy Adoption: Spillover Effects and Their Implications
Authors: Elenev Vadim , Quintero Luis , Rebucci Alessandro , Simeonova Emilia 
Published: November 2024

This paper investigates the direct and spillover effects on mobility caused by the staggered adoption of stay-at-home orders (SHOs) implemented by U.S. counties to contain COVID-19 at the beginning of the pandemic. We find that mobility in neighboring counties declines by a third to a half as much as in the counties that implement the SHOs. Furthermore, these spillovers are concentrated in counties that share media markets with treated counties. Using directional mobility data, we also find that declines in internal mobility in the neighbor counties account for a much larger proportion of the overall decline in mobility than decreases in traffic originating in the treated counties. Together, these results provide strong evidence that SHOs operate through information sharing and voluntary social distancing. Based on our estimates and a simple model of staggered SHO adoption, we construct counterfactual scenarios that separate the impact of policy coordination from that of adoption timing. We find that staggered implementation of SHOs could yield mobility reductions that are larger than coordinated but delayed SHO adoption. This paper was accepted by Carri Chan, healthcare management. Funding: The authors gratefully acknowledge funding from the Hopkins Business of Health Initiative pilot grant program. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2023.01033 .
A Gilded Awakening: Othering the New Woman Narrative in Anzia Yezierska’s Short Fiction
Authors: Abizanda-Cardona María 
Published: November 2024

The Progressive Era’s New Woman, epitomized in Edna Pontellier’s awakening, has been hailed as an icon of feminist rebellion. Recent scholarship, however, has interrogated the subversive potential of this icon, exposing its conservatist purchase on classism, eugenics, and white supremacism. Drawing from this intersectional inquiry into New Woman activism and literary production, this paper examines the short fiction of the Polish-American New Woman writer Anzia Yezierska (1880-1970). Through the appropriation of the awakening narrative, Yezierska sheds light on the failure of the first-wave feminist project to empower women in outsider locations and proposes alternative paths to liberation construed upon the working-class, Jewish values of community and solidarity, thus putting forward an alternative to the exclusionary designs of white feminism and anticipating intersectional demands by second and third wave feminism.
De las mutilaciones físicas, psíquicas y textuales a la "clitorrevolución"
Authors: García Hubard Gabriela 
Published: November 2024

Enfatizando las complejas interrelaciones disciplinares que se han ido tejiendo históricamente en torno al placer femenino, este texto ofrece un recorrido por algunos de los momentos clave de las mutilaciones físicas, psíquicas y textuales del clítoris, principalmente en Europa y Estados Unidos. En un primer momento exhibe que las mutilaciones genitales están presentes en muchas culturas desde la Antigüedad, solo que, bajo el cobijo de la medicina y con un afán de “curar”, se les llama clitorectomías. En un segundo momento muestra que la historia del clítoris tiene distintas aristas, y aunque la más dolorosa es la de las extirpaciones físicas, sería ingenuo pensar que las ablaciones del clítoris no tienen relación con las mutilaciones psíquicas teorizadas por Freud, y con las textuales, que van desde borrar el clítoris de las anatomías hasta la poca presencia que tiene el órgano del placer femenino en la literatura y el cine. Finalmente, se evoca la clitorrevolución, impulsada principalmente desde las artes plásticas.
El adulterio como síntoma: narrativas de la histeria en las novelas decimonónicas
Authors: Nastasescu Diana 
Published: November 2024

La histeria, retirada de los manuales psiquiátricos y tradicionalmente un misterio para los expertos, ha evolucionado hasta ser entendida como una manifestación de emocionalidad y sexualidad femeninas excesivas. Figuras como Freud la reenfocaron hacia la salud mental, añadiéndole dimensiones psicológicas y alejándola del misticismo. Este artículo plantea una revisión de la histeria en las novelas de adulterio de la segunda mitad del siglo XIX para destacar cómo la literatura ha reflejado y perpetuado el estigma de esta enfermedad en las mujeres a partir de las protagonistas de La Regenta, Vilaniu, El primo Basílio, Cécile y Effi Briest. Con un marco teórico extraído de la crítica literaria feminista y de la literatura comparada, se han analizado las tensiones sociales de la época materializadas en la sintomatología histérica y en la sexualidad femenina.
Between Sickness and Sin: The Pathologization of Illicit Love in James Joyce’s Dubliners
Authors: Aláez Corral Máximo 
Published: November 2024

Illicit or non-normative sentimental relationships appear repeatedly in many of the short stories that comprise James Joyce’s Dubliners (1914). This type of emotional link did not have any room in end-of-century Catholic Ireland, and any unorthodox relationship was regarded or punished as sinful and socially unacceptable, following the strict morality of the times. In this article, I intend to analyse some of the most significant stories in Dubliners, in order to dissect the ways in which late nineteenth-century Dublin’s double standards punished any subject steering away from established social norms concerning marriage and acceptable relationships, either by forcing the reclusion of the subjects to the domestic/private sphere or by imposing a normative marriage on them, or even by pushing them to the brink of madness, alcoholism, or suicide.
Characterization of the translational shear properties of the magnetorheological elastomers embedding the tilt chain-like structure
Authors: Lin Dezhao , Gong Di , Yang Fan , Li Ruihong , Zhang Weiqiang 
Published: November 2024

Abstract
In this study, the translational shear characteristics of the magnetorheological elastomers (MREs) with different chain-like structure angles (0°–90° with 15° increment) are tested and analyzed in detail. The experiments are performed under board ranges of strain amplitudes (1–20%), excitation frequencies (0.1–50 Hz), and magnetic fields (0–375 mT). The measured force-displacement data are utilized to analyze the role of chain-like structure angles on the viscoelastic properties together with their dependency on the excitation conditions, mass ratio of magnetic particles, and the magnetic field. The results illustrate that compared with the isotropic MREs and anisotropic MREs with symmetrical chain-like structures, the anisotropic MREs with the tilt chain-like structure can provide more significant variations in the average storage and loss moduli with a slight effect on the zero-field viscoelastic properties, and it exhibits higher frequency and strain dependencies. It can also suggest that the MREs with 30° chain-like structure have the largest MR effect. Besides, the mass ratio of the magnetic particles leads to an increase in the shear modulus of the MREs with the tilt chain-like structure. The test results can provide the fundamental characteristics of MREs for the application design.
Metaphorical meanings of color symbols in literature
Authors: Zhao Qian , Castaneda Abdullah Amalia Qistina 
Published: November 2024

Abstract
In literature, color words serve as important carriers for writers to convey their emotions. In this paper, color words in literary works written by over 30 famous writers from different countries and regions in world literature are selected as the research object. According to the frequency of their use in the selected literary works, our analysis divides the different color symbols into two types: high-frequency and low-frequency. Among the various color symbols, red, blue, white, black, and yellow are classified as high-frequency color symbols. Purple, gray, green, and brown belong to low-frequency color symbols. Comparatively speaking, the metaphorical meanings of high-frequency color symbols are richer and more diverse, while the symbolic meanings of low-frequency color symbols are relatively simple. Through the analysis of the color symbols in the literary works, we find that there is a benign interaction between color symbols and literary works. On the one hand, writers convey their pursuit of art and aesthetics through color symbols. Color symbols become a perfect medium for them to express ideas, show themes, and construct characters. On the other hand, literary works also expand and enrich the metaphorical meaning of color symbols.
Predicting stability factors for rotational failures in earth slopes and embankments using artificial intelligence techniques
Authors: Cemiloglu Ahmed , Cao Yingying , Sabonchi Arkan K. S. , Nanehkaran Yaser A. 
Published: November 2024

Abstract
This study focuses on slope stability analysis, a critical process for understanding the conditions, durability, mass properties, and failure mechanisms of slopes. The research specifically addresses rotational-type failure, the primary instability mechanism affecting earth slopes. Identifying and understanding key factors such as slope height, slope angle, density, cohesion, friction, water pore pressure, and tensile cracks are essential for effective stabilization strategies. The objective of this study is to develop accurate predictive models for slope stability analysis using advanced intelligent techniques, including data mining mapping and complex decision tree regression (DTR). The models were validated using performance metrics such as mean absolute error (MAE), mean squared error (MSE), root mean square error (RMSE), and the coefficient of determination (R²). Additionally, overall accuracy was assessed using a confusion matrix. The predictive model was tested on a dataset of 120 slope cases, achieving an accuracy of approximately 91.07% with DTR. The error rates for the training set were MAE = 0.1242, MSE = 0.1722, and RMSE = 0.1098, demonstrating the model’s capability to effectively analyze and predict slope stability in earth slopes and embankments. The study concludes that these intelligent techniques offer a reliable approach for stability analysis, contributing to safer and more efficient slope management.
Physical intrinsic characteristics of spheroidal particles in coal gasification fine slag
Authors: Li Yijin , Mao Lirui 
Published: November 2024

Abstract
Spheroidal particles constitute the primary particulate signature within coal gasification fine slag (FS) residues. This research endeavor is centered on elucidating the physical configuration and intrinsic attributes of these spheroidal particles and deducing their primary genesis mechanisms through the application of optical microscopy (OM), scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM-EDX), transmission electron microscopy, and field-emission scanning electron microscopy. Notably, the spheroidal particles prevalent in FS predominantly comprise inorganic constituents like aluminum, silicon, and calcium. These particles exhibit a relatively uniform morphology with smooth exteriors and a spectrum of sizes. They predominantly manifest in encapsulated, adhered, and dispersed structural forms. The formation trajectory of these spheroidal particles encompasses multiple phases, encompassing the melting of the ash matrix derived from coal, the coalescence of the liquid phase, internal nucleation processes, layer-by-layer deposition, the bridging and aggregation of minute particles, and growth via precursor-mediated pathways.
Optimization of the road bump and pothole detection technology using convolutional neural network
Authors: Ding Haiping , Tang Qianlong 
Published: November 2024

Abstract
In highway bridge engineering, it is essential to use modern image processing methods to effectively detect and classify road bumps and potholes, considering the unique characteristics of bridge surfaces. Accurate identification and handling of road surface irregularities are crucial for preserving the longevity and security of transportation infrastructure. The study proposes a Convolutional Neural Network for Highway Anomaly Detection (BCNN-HAD) that uses the “BridgeGuard-Vision” (BGV) method, a computer vision technology for highway bridges to increase the accuracy and efficiency of automated image processing for more accurate detection of road irregularities in highway surveillance. Through model training using datasets that imitate various environmental conditions frequently seen on highway bridges, the proposed approach obtains dependable characteristics from photos taken close to bridges, improving flexibility and accuracy. The training method considers variations in lighting, weather conditions, and bridge materials, ensuring the model performs well in various real-world situations. In addition, this work explores the combination of sensor fusion techniques, combining data from many sources such as bridge structural health monitoring systems, cameras, accelerometers, and Global Positioning System. This comprehensive method, represented by BGV-YOLOv5, aims to offer a complete understanding of the bridge surroundings, therefore helping to detect road irregularities and further developing the field of bridge health monitoring. Expected results involve developing a personalized and effective system for detecting road bumps and potholes to tackle specific difficulties in highway bridge situations. In addition, the project seeks to provide a structure for smart transportation systems in the field of bridge engineering. This project seeks to address the particular requirements of highway bridge engineers, improving road safety and infrastructure maintenance methods in highway bridge engineering with the overall objective of establishing a safer and longer-lasting transportation network.
Gestational weight gain and obstetric outcomes in women with obesity in an inner-city population
Authors: Mathur Deepali , Haugland Megan , Leubner Megan , Hovstadius Sara , Wakefield Dorothy , Figueroa Reinaldo 
Published: November 2024

Abstract

Objectives
To describe maternal and perinatal outcomes in patients with BMI ≥30 kg/m2 by BMI class and gestational weight gain.

Methods
Retrospective review of singleton pregnancies with pre-pregnancy BMI ≥30 kg/m2 who received care at our institution between January 1, 2016 and December 31, 2021. Patients were divided into three categories based on BMI (kg/m2): Class I (BMI 30.0–34.9), Class II (BMI 35–39.9), and Class III (BMI≥40) obesity. For gestational weight gain analysis, pregnancies were stratified into three groups: <11 pounds, 11–20 pounds, and >20 pounds. Maternal demographics and outcomes were compared using chi-square analysis, analysis of variance, nonparametric tests, and multivariable regression analysis.

Results
Of 641 patients included, 299 (46.6 %) were in Class I, 209 (32.6 %) in Class II, and 133 (20.7 %) in Class III. Readmission within 6 weeks postpartum, the only outcome found to have a significant difference between BMI categories, was higher in the Class III group (p=0.01). One hundred sixty-two (25.3 %) patients gained <11 pounds, 164 (25.6 %) gained 11–20 pounds, and 313 (48.8 %) gained ≥20 pounds. Greater gestational weight gain was associated with increased rates of cesarean delivery (p<0.001), higher quantitative blood loss (p=0.006), longer length of hospitalization (p=0.03), and higher birthweights (p<0.001).

Conclusions
This represents a unique and actionable opportunity for clinicians to counsel and support their patients in adhering to optimal weight gain targets throughout their pregnancy. Future studies are needed to determine the optimal gestational weight gain recommendations for obese patients.
Hemolytic disease of the fetus and newborn: pregnant person’s and fetal immune systems interaction
Authors: Voto Liliana , Gonzalez Carlos Alberto , Gonzalez Silvana 
Published: November 2024

Abstract
There exists a need to research new diagnostic and therapeutic approaches that consider hemolytic disease of fetus and newborn (HDFN)’s physiopathology and focus not only on the pregnant person’s immune system but also on the fetal immune system. This implies, in the final sense, to view the fetus as our patient. In spite of having found a safe and efficient method of prevention of HDFN more than 50 years ago, HDFN continues to be a relevant cause of perinatal morbidity and mortality, due to lack of access to immunoprophylaxis. In light of the above, we should strive to prevent sensitization and HDFN by ensuring certain health policies across the globe, especially in countries and regions of high morbidity and mortality.
Role of COX6C and NDUFB3 in septic shock and stroke
Authors: Tian Wenbin , Zhang Pei , Yu Ning , Zhu Junyu , Liu Chao , Liu Xuefang , Liu Ya 
Published: November 2024

Abstract

Background
Septic shock is a clinical syndrome characterized by acute circulatory disturbance. Stroke is an acute cerebrovascular disease caused by brain tissue damage. However, the relationship of COX6C and NDUFB3 to them is unclear.

Method
The stroke dataset GSE58294 and the septic shock dataset GSE15491 were downloaded from the gene expression omnibus database. Screening of differentially expressed genes (DEGs), weighted gene co-expression network analysis, construction and analysis of protein–protein interaction network, functional enrichment analysis, gene set enrichment analysis, immune infiltration analysis, and comparative toxicogenomics database (CTD) analysis were performed. Gene expression heat map was drawn. TargetScan screened miRNAs regulating central DEGs.

Results
A total of 664 DEGs were obtained. Gene ontology analysis showed that they were mainly enriched in leukocyte activation, intracellular vesicle, neutrophil activation, and cytokine receptor activity. According to Kyoto Encyclopedia of Genes and Genomes analysis, they are mainly enriched in metabolic pathways, phagosomes, and Staphylococcus aureus infection. Core genes (UQCRQ, USMG5 [ATP5MD], COX6C, NDUFB3, ATP5L [ATP5MG], COX7C, NDUFA1, NDUFA4) were highly expressed in septic shock and stroke samples. CTD analysis found that eight core genes are associated with liver enlargement, inflammation, proliferation, fibrosis, and necrosis.

Conclusion
COX6C and NDUFB3 genes are highly expressed in septic shock and stroke. The higher the COX6C and NDUFB3 genes, the worse the prognosis.