bluuebunny/crossref_metadata_2025_split huggingface dataset:
OSTEOTOMY OF THE CALCANEUS AND CONCOMITANT PLANTAR STRIPPING IN CHILDREN WITH TALIPES CAVO-VARUS
Authors: Dekel S. , Weissman S. L. 
Published: February 2018

1. Thirty-three children with thirty-eight feet affected by a cavo-varus deformity and treated by calcaneal osteotomy with concomitant stripping of plantar muscles were reviewed two to ten years after operation. 2. Out of twenty-six patients who were over eleven years old at the time of the review, fourteen (with eighteen feet) did not need any further treatment. In three other patients the deformity had recurred to a slight degree but did not warrant tarsal reconstruction. In the remaining nine patients the recurrence was marked and necessitated tarsal reconstruction. 3. The combined procedure is of value when there is progressive deformity in children too young for tarsal reconstruction.
RESIDUAL ADDUCTION OF THE FOREFOOT IN TREATED CONGENITAL CLUB FOOT
Authors: Lowe L. W. , Hannon M. A. 
Published: February 2018

1. Seventy-three congenital club feet in fifty-one children have been reviewed between the ages of four and fourteen years to determine the incidence of residual adduction ofthe forefoot. 2. A radiological method of measuring metatarsus varus, based on the naviculo-metatarsal angle, is described. 3. On clinical examination 52 per cent of the feet had residual adduction of the forefoot, and metatarsus varus was present in 74 per cent of these. 4. There was no residual adduction in 48 per cent but only 45 per cent of these showed normal radiographic features. In the remainder various forms of spurious correction were seen. 5. For early treatment, detachment of the origin of the abductor hallucis muscle is recommended at the time of extended posterior release, with tenotomy of the tendon of insertion as an additional measure.
ANTERIOR APPROACH TO SCOLIOSIS
Authors: Dwyer A. F. , Schafer Michael F. 
Published: February 2018

1. The equipment used in the correction of scoliosis by the anterior route is described. 2. The important points in surgical technique are emphasised. 3. The results of operation on fifty-one patients are analysed. 4. Attention is drawn to the high rate of fusion, the stability of correction, and the brevity of the period of convalescence.
THE EFFECT OF HIGH FEMORAL OSTEOTOMY ON OSTEOARTHRITIS OF THE HIP
Authors: Byers Paul D. 
Published: February 2018

1. Osteotomy for osteoarthritis of the hip induces a fibrin layer over the exposed bone which forms the basis of a fibrocellular protective mantle that can differentiate towards cartilage. 2. The process is accompanied by bone remodelling, which reduces sclerosis, resolves osteolytic foci and, in company with bone formation in the fibrous mantle, restores the subchondral plate. 3. Many important aspects of the pathogenesis of osteoarthritis and of its partial repair by osteotomy remain to be elucidated.
ULTRA-STRUCTURE, IN VITRO CULTIVATION AND METABOLISM OF CELLS ISOLATED FROM ARTHRITIC HUMAN BONE
Authors: Bard D. R. , Dickens M. J. , Edwards J. , Smith Audrey U. 
Published: February 2018

1. Methods for culturing cells isolated from slices of arthritic human or normal mammalian cancellous bone are described. 2. The capacity of the cultured cells to take up and hydroxylate labelled proline has been investigated. 3. Sections of the partially decalcified bone and of the isolated cells have been examined by transmission electron microscopy. 4. The possible significance of the results and observations are discussed. We are deeply grateful to Dame Janet Vaughan, who very kindly read this manuscript and made several valuable suggestions and criticisms. We are much obliged to Dr Sylvia Fitton-Jackson for her advice on the techniques of tissue culture and for giving us the composition of her chemically defined medium. Dr Palfrey kindly allowed one of us, M. J. Dickens, to learn transmission electron microscopy in his department at St Thomas's Hospital Medical School under the expert tuition of Mr G. Maxwell. Mr R. Hockhan and Mr M. Hepburn of the University of Surrey Structural Studies Unit helpfully instructed in the operation of the transmission electron microscope. Our special thanks are due to Mr E. P. Morris for his competent and enthusiastic technical assistance.
THE INCIDENCE OF MALIGNANT PRIMARY BONE TUMOURS IN RELATION TO AGE, SEX AND SITE
Authors: Larsson Sven-Erik , Lorentzon Ronny 
Published: February 2018

1. The incidence of osteogenic sarcoma, chondrosarcoma and Ewing's sarcoma in relation to age, sex and site is analysed in a study of 832 malignant primary bone tumours diagnosed in Sweden in 1958-68. The results are compared with those in other series. 2. The adolescent incidence peak for osteogenic sarcoma is caused by tumours localised to the long bones of the lower limb. The peak incidence occurs at a mean age of twelve years for girls and sixteen years for boys and is associated with the maximum growth velocity for the adolescent growth spurt. 3. Ewing's sarcoma, showing no sex difference with regard to its incidence peak, seems not to be associated with bone growth. 4. In the adult, the incidence of osteogenic sarcoma parallels that of chondrosarcoma, thus showing a successive increase with increasing age. In Sweden, where Paget's disease is uncommon, the incidence of osteogenic sarcoma over the age of thirty is only one-third of that during adolescence. 5. In osteogenic sarcoma and chondrosarcoma but not in Ewing's sarcoma, the characteristic predominance of males over females is valid only for localisations to the long bones of the lower limb, the pelvis and the spinal column and not for other sites. Internal factors such as age, sex, bone growth and maturation and also weight-bearing seems to be of importance in modifying the response of the tissue to a causative external factor, like a common virus.
INJURIES OF THE MIDTARSAL JOINT
Authors: Main B. J. , Jowett R. L. 
Published: February 2018

Injuries involving the midtarsal joint, which are frequently misdiagnosed, have been studied to clarify the mechanism, classification and treatment. The necessity for routine antero-posterior, lateral and oblique radiographs is emphasised. Seventy-one injuries have been classified according to the direction of the deforming force : medial, longitudinal compression, lateral, plantar and crush types are described. Included in the medial and lateral types is a hitherto undescribed tarsal rotation or " swivel" injury. The mechanism whereby longitudinal compression causes fractures of the body of the navicular is described, and two varieties having different prognoses are defined : one due to purely longitudinal compression and the other due to longitudinal compression with a medial component. The results of treatment have been assessed clinically and radiologically. Reduction, open if necessary, with internal fixation, is recommended for displaced fractures : primary arthrodesis is not indicated. For severe persistent symptoms from medial and longitudinal force injuries triple arthrodesis is recommended, and from lateral force injuries, calcaneo-cuboid arthrodesis.
THE PATHOLOGICAL BASIS FOR SKELETAL SCINTIGRAPHY
Authors: Galasko C. S. B. 
Published: February 2018

Skeletal scintigraphy, which has now been established as a useful and accurate method of detecting early skeletal metastases and assessing their response to treatment, has been investigated for its pathological basis. Histological examination of several hundred necropsy specimens, from sixty-eight patients who died from malignant disease, showed a significant increase of osteoid and immature woven bone in the presence of metastatic cancer. Tumour-cell suspensions of the VX2 carcinoma were injected into the medullary cavity or on to the periosteal surface of the ilia or tibiae of New Zealand white rabbits. A combination of bone destruction and new bone formation, similar to the autopsy material, was seen. There were at least two mechanisms for the new bone production. Initially, intramembranous ossification was seen in the fibrous stroma surrounding the tumour. Once the cortex was involved and cortical bone destruction had occurred, large amounts of woven bone resembling fracture callus were laid down. The new bone had a markedly increased avidity for boneseeking isotopes, indicating why skeletal scintigraphy was useful. A further twenty rabbits, in whose ilia the VX2 carcinoma was growing, were treated by local irradiation. When treatment was successful the tumour was destroyed, the production of new bone ceased, and the lesion lost its increased avidity for bone-seeking isotopes, indicating that skeletal scintigraphy could be used to assess the response of skeletal metastases to therapy.
INTERCALARY REPLACEMENT OF CANINE FEMORA USING A NEW BIOACTIVE BONE CEMENT
Authors: Senaha Y. , Nakamura T. , Tamura J. , Kawanabe K. , Iida H. , Yamamuro T. 
Published: February 2018

We have developed a bioactive bone cement (BA cement) consisting of Bis-GMA resin and bioactive glass powder. It has high compressive and tensile strengths, a low curing temperature and its bioactivity allows it to bond directly with bone. We operated on the 18 femora of nine mongrel dogs for intercalary replacement of part of the bone by a metal prosthesis using either PMMA cement or BA cement for fixation. Three dogs were killed at each of 4, 12 and 26 weeks after surgery for the evaluation of fixation strength by a push-out test and for histological examination by Giemsa surface staining and SEM. Fixation strengths with PMMA cement at 4, 12 and 26 weeks after surgery were 46.8 ± 18.9, 50.0 ± 24.7, and 58.2 ± 28.9 kgf (mean ±SD), respectively. Those with BA cement were 56.8 ± 26.1, 67.2 ± 19.2, and 72.8 ± 22.2 kgf, respectively. Fibrous tissue intervened between bone and PMMA cement but BA cement had bonded directly to bone at 12 and 26 weeks. This suggests that BA cement will be useful in providing long-lasting fixation of implants to bone under weight-bearing conditions.
KNEE JOINT LOADING AND TIBIAL COMPONENT LOOSENING
Authors: Hilding M. B. , Lanshammar H. , Ryd L. 
Published: February 2018

We report a prospective study of gait and tibial component migration in 45 patients with osteoarthritis treated by total knee arthroplasty (TKA). Migration was measured over two years using roentgen stereophotogrammetry. We used the previously established threshold of 200 μm migration in the second postoperative year to distinguish two groups: a risk group of 15 patients and a stable group of 28 patients. We performed gait analysis before operation and at six months and at two years after TKA. On all three occasions we found significant differences between the two groups in the mean sagittal plane moments of the knee joint. The risk group walked with higher peak flexion moments than the stable group. The two groups were not discriminated by any clinical or radiological criteria or other gait characteristics. The relationship which we have found between gait with increased flexion moments and risk of tibial component loosening warrants further study as regards the aetiology of prosthetic loosening and possible methods of influencing its incidence.
RADIOLOGICAL EVALUATION OF THE INTERFACES AFTER CEMENTED TOTAL HIP REPLACEMENT
Authors: McCaskie A. W. , Brown A. R. , Thompson J. R. , Gregg P. J. 
Published: February 2018

Three radiological methods are commonly used to assess the outcome of total hip replacement (THR). They aim to record the appearance of lucent areas and migration of the prosthesis in a reproducible manner. Two of them were designed to monitor the implant through time and one to grade the quality of cementing. We have measured the level of inter- and intraobserver agreement in all three systems. We randomised 30 patients to receive either finger packing or retrograde gun cementing during Charnley hip replacements. The postoperative departmental radiographs were evaluated in a blinded study by two orthopaedic trainees, two consultants and two experts in THR. The trainees and consultants repeated the exercise at least two weeks later. We used the unweighted kappa statistic to establish the levels of agreement. In general, intraobserver agreement was moderate but interobserver agreement was poor, with levels similar to or less than those expected by chance. Our results indicate that such systems cannot provide reliable data from centres in different parts of the world, with various levels of surgeon evaluating radiographs at differing time intervals. We discuss the problem and suggest some methods of improvement.
SURGICAL EXPERIENCE RELATED TO DISLOCATIONS AFTER TOTAL HIP ARTHROPLASTY
Authors: Hedlundh U. , Ahnfelt L. , Hybbinette C.-H. , Weckström J. , Fredin H. 
Published: February 2018

We studied the effect of surgical experience on the dislocation rate after 4230 primary total hip arthroplasties (THAs) all performed using the posterior approach at three orthopaedic centres at major county hospitals. There were 129 postoperative (3%) dislocations. Twice the number of dislocations were registered for inexperienced surgeons as for their more experienced colleagues. This frequency of dislocation levelled off with increasing numbers of operations and remained constant after approximately 30. For every ten primary THAs performed annually, the risk of dislocation decreased by 50%.
THE FREQUENCY OF VENOUS THROMBOSIS IN CEMENTED AND NON-CEMENTED HIP ARTHROPLASTY
Authors: Laupacis A. , Rorabeck C. , Bourne R. , Tugwell P. , Bullas R. , Rankin R. , Vellet A. D. , Feeny D. , Wong C. 
Published: February 2018

We randomised 250 patients undergoing unilateral, elective hip arthroplasty for osteoarthritis to receive either a cemented or a non-cemented Mallory Head prosthesis. Aspirin was used as prophylaxis against thromboembolism during the first half of the study and adjusted-dose warfarin during the second half. Postoperatively, all patients were asked to have bilateral venography and 80% agreed. All were evaluated clinically for pulmonary embolism. There was no difference in the frequency of deep-venous thrombosis between the two groups (50% cemented v 47% non-cemented, p = 0.73; 95% CI of the difference −13.6% to 19.3%). Three of the 64 patients (5%) in whom venography had demonstrated isolated distal thrombi developed pulmonary emboli.
PATELLAR RESURFACING VERSUS RETENTION IN TOTAL KNEE ARTHROPLASTY
Authors: Feller J. A. , Bartlett R. J. , Lang D. M. 
Published: February 2018

We studied 40 patients in whom the patella was not severely deformed and who were undergoing primary total knee arthroplasty (TKA) for osteoarthritis by one surgeon using one type of prosthesis. They were randomly allocated either to have the patella retained or resurfaced with a cemented, all-polyethylene component regardless of the state of the patellar articular cartilage. Apart from removal of osteophytes, no surgery was undertaken on the retained patellae. All 38 surviving patients were evaluated at three years using the HSS knee score and a new, specifically designed Patellar score (maximum score of 30). No TKA was revised, but two patients in the resurfacing group had a further unrelated procedure. The mean HSS and Patellar scores at follow-up were 89 and 28 in the patellar retention group and 83 and 26 in the patellar resurfacing group. Statistically significant lower scores for both were recorded in women and in heavier patients. Stair-climbing ability was significantly better in the retention group. Although there were no complications related to patellar resurfacing, in the medium term we did not find any significant benefit from resurfacing the patella during TKA for osteoarthritis if it was not severely deformed.
ANALGESIC EFFECT OF EXTRACORPOREAL SHOCK-WAVE THERAPY ON CHRONIC TENNIS ELBOW
Authors: Rompe J. D. , Hopf C. , Küllmer K. , Heine J. , Bürger R. 
Published: February 2018

We report a controlled, prospective study to investigate the effect of treatment by low-energy extracorporeal shock waves on pain in tennis elbow. We assigned at random 100 patients who had had symptoms for more than 12 months to two groups to receive low-energy shock-wave therapy. Group I received a total of 3000 impulses of 0.08 mJ/mm2 and group II, the control group, 30 impulses. The patients were reviewed after 3, 6 and 24 weeks. There was significant alleviation of pain and improvement of function after treatment in group I in which there was a good or excellent outcome in 48% and an acceptable result in 42% at the final review, compared with 6% and 24%, respectively, in group II.
STRUCTURAL BULK ALLOGRAFTS IN ACETABULAR RECONSTRUCTION
Authors: Hooten J. P. , Engh C. A. , Heekin R. D. , Vinh T. N. 
Published: February 2018

Two acetabula which contained large bone allografts introduced at revision arthroplasty were obtained at post-mortem. The allografts had been placed in superior defects to support cementless acetabular components, and both hips were functioning well at the time of death. Clinical radiographs demonstrated apparent healing of graft to host bone, no graft collapse and stability of the acetabular components. Microscopic examination of sections through these specimens showed that the bulk allografts were encapsulated in fibrous tissue. Vascularity was increased at the host-graft interface, but there was limited evidence of bone union between the graft and the host. In the few areas where union had occurred, revascularisation extended no more than 2 mm beyond the graft-host interface. Within the body of the graft, the acellular matrix of trabecular bone maintained structural integrity up to 48 months after surgery. In areas where the allograft was adjacent to an implant, there was fibrous tissue orientated parallel to the implant surface. The acetabulum which contained a porous-coated component showed evidence of bone growth into the porous surface where it was in contact with viable host bone. No ingrowth occurred in areas where the porous coating was in contact with the graft. Although the grafts were functioning well, allograft revascularisation and remodelling were minimal, and the radiological appearance of healing did not correlate with histological findings.
PROSPECTIVE CLINICAL AND JOINT SIMULATOR STUDIES OF A NEW TOTAL HIP ARTHROPLASTY USING ALUMINA CERAMIC HEADS AND CROSS-LINKED POLYETHYLENE CUPS
Authors: Wroblewski B. M. , Siney P. D. , Dowson D. , Collins S. N. 
Published: February 2018

We report the findings from independent prospective clinical and laboratory-based joint-simulator studies of the performance of ceramic femoral heads of 22.225 mm diameter in cross-linked polyethylene (XLP) acetabular cups. We found remarkable qualitative and quantitative agreement between the clinical and simulator results for the wear characteristics with time, and confirmed that ceramic femoral heads penetrate the XLP cups at only about half the rate of otherwise comparable metal heads. In the clinical study, 19 hips in 17 patients were followed for an average of 77 months. In the hip-joint simulator a similar prosthesis was tested for 7.3 million cycles. Both clinical and simulator results showed relatively high rates of penetration over the first 18 months or 1.5 million cycles, followed by a very much lower wear thereafter. Once an initial bedding-in of 0.2 mm to 0.4 mm had taken place the subsequent rates of penetration were very small. The initial clinical wear during bedding-in averaged 0.29 mm/year; subsequent progression was an order of magnitude lower at about 0.022 mm/year, lower than the 0.07 mm/year in metal-to-UHMWP Charnley LFAs. Our results show the excellent tribological features of alumina-ceramic-to-XLP implants, and also confirm the value of well-designed joint simulators for the evaluation of total joint replacements.
ANTERIOR RELEASE FOR FIXED FLEXION DEFORMITY OF THE HIP IN SPINA BIFIDA
Authors: Frawley P. A. , Broughton N. S. , Menelaus M. B. 
Published: February 2018

We reviewed the results of anterior hip release for fixed flexion deformity in 57 hips in 38 children with spina bifida at an average follow-up of 8.9 years (2 to 22). The indication for this operation was a fixed flexion deformity of more than 30° which interfered with function. In 43 hips there was a good outcome in that the fixed flexion deformity remained less than 30° at follow-up. Four hips had a good initial result but deteriorated after an average of five years, and ten had a poor outcome with deformity of over 30°. Six hips required a repeated anterior hip release and two of these were successful. The success of anterior hip release could not be related to the neurological level or the age at operation. Successful surgery correlated with the walking ability of the child at the latest follow-up.
BIOMECHANICAL PROPERTIES OF CORTICAL ALLOGRAFT BONE USING A NEW METHOD OF BONE STRENGTH MEASUREMENT
Authors: Hamer A. J. , Strachan J. R. , Black M. M. , Ibbotson C. J. , Stockley I. , Elson R. A. 
Published: February 2018

There have been conflicting reports on the effects of gamma irradiation on the material properties of cortical allograft bone. To investigate changes which result from the method of preparation, test samples must be produced with similar mechanical properties to minimise variations other than those resulting from treatment. We describe a new method for the comparative measurement of bone strength using standard bone samples. We used 233 samples from six cadavers to study the effects of irradiation at a standard dose (28 kGy) alone and combined with deep freezing. We also investigated the effects of varying the dose from 6.8 to 60 kGy (n = 132). None of the treatments had any effect on the elastic behaviour of the samples, but there was a reduction in strength to 64% of control values (p < 0.01) after irradiation with 28 kGy. There was also a dose-dependent reduction in strength and in the ability of the samples to absorb work before failure We suggest that irradiation may cause an alteration in the bone matrix of allograft bone, but provided it is used in situations in which loading is within its elastic region, then failure should not occur.
PATHOLOGICAL FRACTURES OF THE PROXIMAL FEMUR WITH IMPENDING SHAFT FRACTURES TREATED BY THR AND CEMENTED INTRAMEDULLARY NAILING
Authors: Voggenreiter G. , Assenmacher S. , Klaes W. , Schmit-Neuerburg K.-P. 
Published: February 2018

We have used total hip replacement combined with cemented intramedullary nailing to treat a selected group of nine patients with pathological fractures of the proximal femur and impending fractures of the shaft due to metastases. One patient died from cardiopulmonary failure on the third postoperative day, but the others were able to walk within the first week after operation. Complications included one recurrent dislocation of the THR and one fracture of an osteolytic lesion of the femoral shaft during nail insertion. Both were managed successfully. The hybrid osteosynthesis which we describe is an alternative to the use of tumour or long-stem prostheses; it has the advantage of preserving bone stock and muscle attachments.
MAGNETIC RESONANCE IMAGING OF PATELLAR TENDONITIS
Authors: Johnson D. P. , Wakeley C. J. , Watt I. 
Published: February 2018

The radiological and MRI appearances of 24 knees with patellar tendonitis resistant to conservative therapy were analysed to identify the characteristic MRI appearance and to determine if the patellar morphology was abnormal. A significant thickening of the tendon was found in all cases; this was a more reliable diagnostic feature than a high signal within the superior posterior and central aspect of the tendon at its proximal attachment The site of the lesion shown by MRI is more compatible with impingement of the inferior pole of the patella against the patellar tendon than a stress overload of the tendon. There were no significant differences in the length of the patella, inferior pole or length of the articular surface when the patellar morphology was compared with that of a matched control group.