bluuebunny/crossref_metadata_2025_split huggingface dataset:
Entre deusas, ciborgues e o perigo de (querer) ver tudo
Authors: Albuquerque Mariana Imbelloni Braga 
Published: April 2019

RESUMO
O presente artigo propõe um diálogo entre as propostas de conhecimento localizado e a crítica a determinados usos da teoria intersecional não comprometidos com a justiça social. A partir deste diálogo, pensa as implicações do conhecimento localizado nas discussões feministas racializadas.
PALAVRAS- CHAVE: Conhecimento Localizado. Intersecionalidade. Agenciamento.
Terminologiedatenaustausch mit TERMDAT – Passgenaue Schnittstellen für die Terminologiedatenbank der Schweizerischen Bundeskanzlei
Authors: Reineke Detlef 
Published: April 2019

Abstract
The terminology database TERMDAT is at the very heart of the Terminology Section of the Swiss Federal Chancellery’s Central Language Services. It provides Swiss legal and administrative terminology predominantly for the four national languages German, French, Italian, and Romansh (plus English). However, data exchange with cooperating actors (Federal Departments, cantons, external service providers, etc.) constitutes a particular challenge, since these actors operate with different systems and data models. The present article describes a solution developed within a pilot project aiming at providing means to substantially improve data flow within a highly heterogeneous database landscape.
The Immigrant Parent Disadvantage: Parent Linguistic Capital and Student School Performance
Authors: Fontana Jason J. 
Published: April 2019

Researchers, teachers and policy makers continue to wrestle with understanding why children of immigrants perform more poorly in school than their counterparts with native born parents. While parental involvement through checking of homework and participation in school events have been identified as relevant factors, the findings of research are not conclusive. This study re-examines the relationships of these two factors with school performance among the children of Spanish-speaking immigrants by introducing a third variable: parental English proficiency. The results reveal that after controlling for parental English proficiency, homework checking no longer has a significant impact and the effect of parental school involvement is reduced; English language abilities of parents, on the other hand, have a significant effect on student performance. This finding suggests that improving parental English proficiency and cultural awareness can produce a positive impact on the school performance of the children of non-native English speaking parents.
A Horse Derby, A Missed Connection, and Hiking through the Alps: John Dewey's 1928 visit to the Soviet Union
Authors: Ryabyy Vladislav 
Published: April 2019

After December 6, 1917, the government of the United States led by President Woodrow Wilson decided not to recognize the new government of Russia, which was led by the Bolshevik Party. Some of the reasons for this lack of recognition came from the Bolshevik government’srefusal to honor prior debits owed by the Tsarist government and the seizure of American property. The next three presidents would continue this policy.1 For the next sixteen years, many Americans visited and wrote about the Soviet Union. Amongst those visitors was a delegation of twenty-five who visited the Soviet Union in the summer of 1928. Their stated purpose was to,“study methods of public instruction in Soviet Russia this summer.” 2 The most influential amongst the twenty-five was John Dewey, a professor of philosophy at Colombia University and one of the leading educational reformers in the United States. In the time during and after this trip Dewey wrote a series of articles for the “New Republic” and later collected these articles andplaced them in his book, Impressions of the Revolutionary World.3 This book also dealt with his travels to China in 1920, Turkey in 1924, and Mexico in 1926. This book does not tell the full story of the trip. By analyzing his letters that he sent during this time, one can recreate a partial itinerary of his daily activities and those that he met with. Those letters also reveal that this trip influenced not only the twenty-five educators from the United States but also had an impact on Soviet educators because they had the ability to finally meet the man that they had studied for so long. The United States Department of State was also interested in this trip and used it to learn more about the Soviet Union. The Department of State was also dealing with anticommunism at this time and this caused Dewey’s trip to be closely monitored. The New York Times and other newspapers reported on this trip and the aftermath of this trip can be seen through these reports. This trip impacted not only those within the Soviet Union but also the State Departments and the American public’s view of the Soviet Union.
Degree of MDM2 Amplification Affects Clinical Outcomes in Dedifferentiated Liposarcoma
Authors: Bill Kate Lynn J. , Seligson Nathan D. , Hays John L. , Awasthi Achal , Demoret Bryce , Stets Colin W. , Duggan Megan C. , Bupathi Manojkumar , Brock Guy N. , Millis Sherri Z. , Shakya Reena , Timmers Cynthia D. , Wakely Paul E. , Pollock Raphael E. , Chen James L. 
Published: April 2019

Abstract

Background
Dedifferentiated liposarcomas (DDLPS) are mesenchymal tumors associated with universally poor response to treatment. Genomic amplification of murine double minute 2 (MDM2) is used as a diagnostic biomarker; however, no established biomarkers exist to guide DDLPS treatment. In the largest study of its kind, we report that the extent of MDM2 amplification, not simply the presence of MDM2 amplification, may be biologically important to the actions of DDLPS.

Patients and Methods
The distribution of MDM2 amplification in DDLPS was assessed using data from a commercial sequencing laboratory (n = 642) and The Cancer Genome Atlas (n = 57). Data from two retrospective clinical trials (n = 15, n = 16) and one prospective clinical trial (n = 25) were used to test MDM2’s utility as a clinical biomarker. in vitro and in vivo assessments were conducted in DDLPS cell lines.

Results
Genomic MDM2 amplification follows a highly reproducible log-normal distribution. In patients with DDLPS treated with complete tumor resection, elevated MDM2 was associated with shortened time to recurrence as measured by genomic amplification (p = .003) and mRNA expression (p = .04). In patients requiring systemic therapy, higher MDM2 amplification was associated with reduced overall survival (p = .04). Doxorubicin treatment of DDLPS cells in vitro demonstrated variable sensitivity based on baseline MDM2 levels, and doxorubicin treatment elevated MDM2 expression. In vivo, treatment with doxorubicin followed by an MDM2 inhibitor improved doxorubicin sensitivity.

Conclusion
MDM2 amplification levels in DDLPS follow a reproducible distribution and are associated with clinical outcomes and drug sensitivity. These results suggest that a prospective study of MDM2 as a predictive biomarker in DDLPS is warranted.
El tratamiento de la mitología en los dramas con música realizados para ámbitos privados en la primera mitad del siglo XVIII
Authors: Presas Villalba Adela 
Published: April 2019

RESUMENAparte de las funciones teatrales y cortesanas, de gran aparato escénico, existió durante el siglo XVIII la costumbre de representar zarzuelas, y otros tipos de obras dramáticas con música, tanto en casas particulares como en ámbitos privados, escolares o culturales. Es además constatable que estas obras estuvieron siempre basadas en la mitología, y aunque este es un rasgo común en el teatro músico del siglo XVII y de la primera mitad del XVIII en España, es interesante observar si recibe, en este caso, un tratamiento diferenciado. En el presente artículo se plantea la interacción que se produce entre el elemento musical (formato y contenido textual) y la temática mitológica en estas obras dedicadas a un público diferente al de los teatros, ya sean cortesanos o populares, y para un entorno privado que contaba, además, con unas limitaciones evidentes tanto en el aspecto escenográfico como, especialmente, en el musical.PALABRAS CLAVEZarzuela, mitología, teatro musical español, siglo XVIII, funciones privadas. TITLEThe treatment of mythology in dramas with music made for private circles in the fi rst half of the 18th centuryABSTRACTApart from the theatrical and court performances, of great scenic apparatus, there was during the eighteenth century the custom of representing zarzuelas, and other types of dramatic works with music, both in homes as well as in private school and cultural areas. It is also verifiable that these works were always based on mythology, and although this is a common feature in the music theatre of the seventeenth century and first half of the eighteenth century in Spain, it is interesting to note whether it receives, in this case, a differentiated treatment. This article puts forward the interaction between the musical element (format and textual content) and the mythological subject in these works devoted to a different audience than that of the theatres, either court or popular, and for a private milieu which had, in addition, obvious limitations both in the scenography and, especially, in the musical features.KEY WORDSZarzuela, mythology, Spanish musical theatre, eighteenth century, private performance.
La tradición clásica en la obra poética de Manuel Fermín de Laviano. Apuntes para su estudio
Authors: Escalante Varona Alberto 
Published: April 2019

RESUMENEn este artículo se propone un estudio de dos poemas de Manuel Fermín de Laviano como ejemplo de poemas de encomio, dentro de la tradición dieciochesca: los "Endecasílabos a los Infantes Gemelos" y el "Canto al Arco del Duque de Híjar". Se rastrea la influencia de la tradición clásica en la composición de estos textos. Para ello, se propone un modelo de análisis atendiendo a la incidencia genérica y relación cultural entre los textos clásicos y la literatura occidental moderna. A continuación, se comentan ambos poemas: editamos también el "Canto".PALABRAS CLAVEGenethliakón, géneros epidícticos, poesía de circunstancias, Carlos IV. TITLEThe Classical Tradition in Manuel Fermín de Laviano’s Poetic Texts. Some Notes for its StudysABSTRACTIn this paper, we study two poems by Manuel Fermín de Laviano, as encomium poems in the Spanish Enlightenment tradition: the "Endecasílabos a los Infantes Gemelos" and the "Canto al Arco del Duque de Híjar". We search for the influence of Classical Tradition in the writing process of these texts. For that purpose, we analyse both poems due to its generic characteristics and the cultural relationship between them and classical literature. At last, we comment them, and we edite the "Canto".KEY WORDSGenethliakon, epideictic genres, circumstances poetry, Charles IV.
Two mathematical approaches to study the phosphorus eutrophication of a wetland in Puerto Rico
Authors: Paredes Gutiérrez Marlio , Torres Velasquez Brenda Carolina , Sanchez Colon Yashira Marie , Schaffner Gibbs Fred Charles 
Published: April 2019

Introduction: Laguna Cartagena (LC), a wetland in Lajas, Puerto Rico, has been negatively impacted by nutrients, mainly phosphorus run-off from agricultural activities until the end of sugar cane cultivation in the late 1900s. This led to P concentration remain high at hypereutrophic state that was irremediable even after a 5-fold reduction in source water nutrient concentration.
Objective: The main goal of this research paper is to apply two different mathematical approaches to assess the eutrophication level of a wetland in Puerto Rico.
Method: Grey Cluster Method (GCM) was used to classify LC’s eutrophic state by applying the International and Chinese trophic standards and two parameters, total phosphorous (TP) and total nitrogen (TN). Mean TP and TN from LC consolidated bottom substrate and flocculence samples were used to classify LC. To address whether LC can recover, soluble reactive phosphorus (SRP) and TP from LC inlet, outlet and center water samples were used to model (differential equation) the input and loss of phosphorus in LC and determine whether an equilibrium point exists. GCM analysis classified LC as a eutrophic wetland using the International standard and hypereutrophic using the Chinese standard.
Results: Trophic state classification did not vary with use of consolidated bottom substrate versus flocculence samples. The differential equation model showed that SRP and TP levels within LC were higher than levels of SRP and TP entering LC, which could be caused by a nutrient recycling process within LC that may predict failure of remediation efforts. An equilibrium point was found at the eutrophic level, which means that even if there is a reduction in phosphorus input, there will not be a change in LC’s eutrophic state.
Conclusions: Chinese trophic standard indicated LC was in a hypertrophic state. Similar results were found using the international standard. The differential equation model showed that LC is irreversible.
Therapeutic evaluation of efficacy of intralesional bleomycin in common warts including palmo-plantar and periungual warts: a prospective study
Authors: Kumar Prabal , Mehta Karaninder Singh , Mahajan Vikram , Chauhan Pushpinder Singh 
Published: April 2019

<p class="abstract"><strong>Background:</strong> Commonly used destructive treatment modalities for common warts though effective, are associated with pigmentary changes, scarring and recurrences. Treatment with immune modulators or immunotherapy has shown variable results. We evaluated efficacy and safety of intralesional bleomycin for treating common warts including palmoplantar and periungual warts.</p><p class="abstract"><strong>Methods:</strong> Two hundred patients with common, palmar, plantar and periungual warts (having 753 warts) were treated with two intralesional injections of bleomycin 1 mg/ml at two weekly intervals. They were followed up at 4weeks and 12 weeks for cure, adverse effects and partial clearance or recurrence.<strong></strong></p><p class="abstract"><strong>Results:</strong> Only 183 (M: F 95:88) patients having 703 warts completed the study. Overall, complete clearance in 669 (95.16%) warts in 156 (85.2%) patients and partial clearance in 24 (3.4%) warts in 21 (11.4%) patients were observed. Patients with complete/partial clearance were highly satisfied from the treatment. Recurrence was seen in 6 (3.27%) patients. Most patients had injection site pain for 2-3 days not warranting discontinuation of treatment. Other adverse effects included temporary hyperpigmentation in 46, altered skin texture in 12 and injection site infection in 6 patients, respectively.</p><p><strong>Conclusions:</strong> Intralesional bleomycin appears effective, safe, and acceptable treatment modality for common warts including palmoplantar and periungual warts. It carries the advantage of low dose, insignificant adverse effects and high patient satisfaction. </p>
The Diagnostic Accuracy of an Intelligent and Automated Fundus Disease Image Assessment System with Lesion Quantitative Function (SmartEye) in Diabetic Patients
Authors: XU Yi , WANG Yongyi , LIU Bin , TANG Lin , LV Liangqing , LU Lina , KE Xin , LING Saiguang , ZOU Haidong 
Published: April 2019

Abstract
Background

With the diabetes mellitus (DM) prevalence increasing annually, the human grading of retinal images to evaluate DR has posed a substantial burden worldwide. SmartEye is a recently developed fundus image processing and analysis system with lesion quantification function for DR screening. It is sensitive to the lesion area and can automatically identify the lesion position and size. We reported the diabetic retinopathy (DR) grading results of SmartEye versus ophthalmologists in analyzing images captured with non-mydriatic fundus cameras in community healthcare centers, as well as DR lesion quantitative analysis results on different disease stages.

Methods

This is a cross-sectional study. All the fundus images were collected from the Shanghai Diabetic Eye Study in Diabetics (SDES) program from Apr 2016 to Aug 2017. 19904 fundus images were acquired from 6013 diabetic patients. The grading results of ophthalmologists and SmartEye are compared. Lesion quantification of several images at different DR stages is also presented.

Results

The sensitivity for diagnosing no DR, mild NPDR (non-proliferative diabetic retinopathy), moderate NPDR, severe NPDR, PDR (proliferative diabetic retinopathy) are 86.19%, 83.18%, 88.64%, 89.59%, and 85.02%. The specificity are 63.07%, 70.96%, 64.16%, 70.38%, and 74.79%, respectively. The AUC are PDR, 0.80 (0.79, 0.81); severe NPDR, 0.80 (0.79, 0.80); moderate NPDR, 0.77 (0.76, 0.77); and mild NPDR, 0.78 (0.77, 0.79). Lesion quantification results showed that the total hemorrhage area, maximum hemorrhage area, total exudation area, and maximum exudation area increase with DR severity.

Conclusions

SmartEye has a high diagnostic accuracy in DR screening program using non-mydriatic fundus cameras. SmartEye quantitative analysis may be an innovative and promising method of DR diagnosis and grading.
Improving Perception and Confidence Toward Bystander Cardiopulmonary Resuscitation and Public Access Automated External Defibrillator Program: How Does Training Program Help?
Authors: Liaw Siew Yee , Chew Keng Sheng , Zahedi Ahmad Zulkarnain Ahmad , Wong Shirly Siew Ling , Singmamae Nariman , Kaushal Dev Nath , Chan Hiang Chuan 
Published: April 2019

Abstract
Background: In conjunction with an automated external defibrillator (AED) placement program at various locations within a public university in Malaysia, a series of structured training programs were conducted. The objectives of this study is to (1) evaluate the effectiveness of a structured training program in improving the perception of the importance of AED and CPR (2) evaluate the confidence of the employees in using an AED and performing bystander CPR (3) identify the fears and concerns of these employees in using AED and performing CPR (4) determine the perception of these employees towards the strategy of the AEDs placed at various locations within the university.
Methods: In this single center observational study, a validated questionnaire aimed to assess the university employees' attitude and confidence in handling AED and performing CPR before (pre-test) and immediately after (post-test) the training program was conducted.
Results: A total of 184 participants participated om this study. Using Wilcoxon signed-rank test, the training programs appeared to have improved the perception that “using AED is important for unresponsive victims” (z = 4.32, p<0.001) and that “AED practice drills should be performed on a regular basis” (z = -2.41, p = 0.02) as well as increased the confidence to perform CPR (z = -8.56, p<0.001), use AED (z = -8.93, p<0.001), identify victims with no signs of life (z = -7.88, p<0.001) and the willingness to perform CPR and AED without hesitancy (z = -8.91, p<0.001). Fears and concerns on performing CPR and using AED also appeared to have been significantly reduced and the perception on placement strategies of these AEDs were generally positive.
Conclusion: Using the theory of planned behavior as the explanatory framework, training programs appears to be helpful in improving the perception and the confidence of the participants towards performing CPR and using AED through the promotion of positive attitude, positive societal expectation and a positive sense of empowerment. But whether this positive effect will translate into actual CPR performance and AED application in a real cardiac arrest is yet to be seen.
Cytomegalovirus Seroprevalence and Titres in Solid Organ Transplant Recipients and Non-transplant Individuals in Seoul, South Korea
Authors: La Yeonju , Kwon Da Eun , Yoo Seul Gi , Lee Kyoung Hwa , Han Sang Hoon , Song Young Goo 
Published: April 2019

Abstract
Background: Cytomegalovirus (CMV) can cause poor outcomes in solid organ transplant (SOT) recipients and have relation to cardiovascular diseases (CVD) in general population. The anti-CMV immunoglobulin G (IgG) seroepidemiology is useful for identifying the risk of post-SOT CMV infection or disease as well as immunosenescence or CVD. However, recent CMV seroprevalence and titre have not been fully evaluated with respect to age distribution and comparison between SOT recipients and non-transplant individuals.
Methods: We retrospectively retrieved all anti-CMV IgG results from 12658 individuals aged of > one years screened between July 2006 and Nov. 2017 at the Severance Hospital at Seoul. The cohort excluding hematopoietic stem cell transplant recipients and subjects with equivocal values included 2184 SOT recipients and 9738 non-transplant individuals. All IgG results in SOT recipients were measured at pre-transplant period, and only first values among subjects with repeated tests were included in the analyses.
Results: The overall IgG seroprevalence and titres were significantly higher among SOT recipients relative to non-transplant individuals (98.7% vs. 94.8%, p < 0.001 and 64.7 ± 44.3 vs. 54.7 ± 38.9 arbitrary units [aU]/mL, p < 0.001, respectively). The lowest seropositive rates were observed among both SOT recipients and non-transplant individuals aged 11–15 years (70.6% and 70.2%, respectively). The frequency of seropositivity among adults aged ≥ 41 years increased to ≥ 99% in both groups. Age and SOT group were independently associated factors with higher CMV seroprevalence (OR, 1.12, 95% CI, 1.11-1.12, p < 0.001 and OR 2.43, 95% CI, 1.65-3.59, p < 0.001, respectively). Although liver (99.7%, 80.1 ± 54.5 aU/mL) and lung (100%, 84.3 ± 68.3 aU/mL) transplants had significantly higher seropositive rates and titres compared to kidney (98.3%, 59.4 ± 36.1 aU/mL) and heart (97.0%, 58.1 ± 46.9 aU/mL) transplant (overall p = 0.024 and < 0.001, respectively), the different transplant organs did not affect the seroprevalence in multivariate regression analysis.
Conclusions: CMV seropositivity was lowest among school-aged children. IgG testing revealed that most adult SOT recipients in South Korea faced an intermediate serostatus risk of post-transplant CMV infection and disease.