bluuebunny/crossref_metadata_2025_split huggingface dataset:
Increased Prevalence of Concomitant Psychiatric Diagnoses Among Patients Undergoing Hip Arthroscopic Surgery
Authors: Iglinski-Benjamin Kag C. , Xiao Michelle , Safran Marc R. , Abrams Geoffrey D. 
Published: January 2019

Background: Active patients with musculoskeletal pain are not immune to psychological or psychiatric disease. Observations suggest that patients undergoing hip arthroscopic surgery may have an increased prevalence of comorbid psychiatric conditions. Hypothesis: Patients undergoing hip arthroscopic surgery have an increased prevalence of concomitant psychiatric diagnoses compared with the general population as well as those undergoing anterior cruciate ligament (ACL) reconstruction. Study Design: Case-control study; Level of evidence, 3. Methods: A retrospective review of a medical claims database spanning from 2007 to 2016 was utilized to identify patients with a Current Procedural Terminology (CPT) code indicating that they had undergone hip arthroscopic surgery. This group was then dichotomized to those with or without an International Classification of Diseases, 9th Revision (ICD-9) and 10th Revision (ICD-10) diagnosis code indicating a psychological or psychiatric condition at any time before hip arthroscopic surgery or up to 2 years after hip arthrscopic surgery. As a control, ICD-9 and ICD-10 diagnosis codes for psychological or psychiatric conditions were determined in patients without a CPT code for hip arthroscopic surgery (general population) as well as for 2 surgical groups: those undergoing ACL reconstruction and those undergoing shoulder stabilization surgery. Prevalence was determined in all groups and compared using chi-square analysis. Results: There were 22,676,069 patients in the database, with 2428 undergoing hip arthroscopic surgery. Those undergoing hip arthroscopic surgery had a 3-fold increased prevalence of concomitant psychiatric diagnoses compared with the general population (52% vs 17%, respectively; P < .0001). There was a significant difference in the prevalence of psychiatric diagnoses in the hip arthroscopic surgery group between male and female patients (46% vs 56%, respectively; P = .0061), with depression and anxiety being the 2 most common comorbid conditions. Those undergoing hip arthroscopic surgery also had a significantly increased prevalence of concomitant psychiatric diagnoses versus those undergoing ACL reconstruction (52% vs 28%, respectively; P < .0001) as well as those undergoing shoulder stabilization surgery (52% vs 42%, respectively; P < .0001). Conclusion: Patients undergoing hip arthroscopic surgery had an increased prevalence of comorbid psychiatric conditions compared with the general population as well as those undergoing ACL reconstruction or shoulder stabilization surgery. Depression and anxiety were the most prevalent concomitant psychiatric diagnoses.
EGFR plasma mutation in prediction models for resistance with EGFR TKI and survival of non‐small cell lung cancer
Authors: Phan Thang Thanh , Tran Bich‐Thu , Nguyen Son Truong , Ho Toan Trong , Nguyen Hang Thuy , Le Vu Thuong , Le Anh Tuan 
Published: January 2019

AbstractBackgroundThis study aims to clarify the prognostic role of epidermal growth factor receptor (EGFR) mutations in plasma of non‐small cell lung cancer (NSCLC) for resistance to tyrosine kinase inhibitor (TKI), in correlation with clinical characteristics. A total of 94 Adenocarcinoma, clinical stage IV NSCLC patients with either E19del or L858R mutation were admitted to the prospective study from Jan‐2016 to Jul‐2018. EGFR mutations in plasma were detected by scorpions ARMS method. The Kaplan–Meier and Cox regression methods were used to estimate and test the difference of progression‐free survival (PFS) and overall survival (OS) between groups. The prognostic power of each factor was appraised by the Bayesian Model Averaging (BMA) method.ResultsAmong 94 patients, 28 cases still are good responses according to the RECIST criteria and negative for EGFR mutations in plasma. Of 66 resistant patients, EGFR mutations were positive in plasma of 57 cases (86.4%) which was higher than the value of pre‐treatment (48.5%). Of which, 17 patients (25.8%) have the occurrence of EGFR mutations in plasma earlier than progression 2.1 (0.6–7.9) months. The secondary T790M mutation was found in the plasma of 32 cases (48.5%). Median PFS and OS for the study subjects were 12.9 (11.0–14.2) and 29.5 (25.2–41.3) months, respectively. The post‐treatment EGFR plasma test with brain and new metastasis were detected as independent prognostic factors for worse PFS (P = 0.008, 0.016 and 0.028, respectively). While EGFR plasma (P = 0.044) with bone metastasis at baseline (P = 0.012), new metastasis (P = 0.003), and high cfDNA concentration (P = 0.004) serve as the worse survival factors, surgery treatment helps to prolong OS in NSCLC treated with EGFR TKI (P = 0.012). BMA analysis identified EGFR plasma test as the strongest prognostic factor for both PFS and OS (possibility of 100% and 99.7%, respectively).ConclusionsEGFR plasma test is the powerfully prognostic factor for early resistance with EGFR TKI and worse survival in NSCLC regardless of clinical characteristics.
After Trans Studies
Authors: Chu Andrea Long , Harsin Drager Emmett 
Published: January 2019

Abstract
This dialogue contends with the state of trans studies today. While the authors differ in their levels of optimism for its future, they both agree that if trans studies is to survive, it must be able articulate a fresh set of reading practices distinct from, or even at odds with, those of queer studies. Revisiting Sandy Stone's field-defining 1991 essay “The Empire Strikes Back,” they note that trans studies paradoxically begins with a call to abandon the figure of the transsexual, imagined solely as a normative medical category. In contrast, the authors argue that the critical value of the transsexual lies precisely in her being an obstacle to romantic narratives of antinormative queerness.
β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin
Authors: Cui Shuang , Li Liang , Yu Ruth T. , Downes Michael , Evans Ronald M. , Hulin Julie-Ann , Makarenkova Helen P. , Meech Robyn 
Published: January 2019

ABSTRACT
Canonical Wnts promote myoblast differentiation; however, the role of β-catenin in adult myogenesis has been contentious, and its mechanism(s) unclear. Using CRISPR-generated β-catenin-null primary adult mouse myoblasts, we found that β-catenin was essential for morphological differentiation and timely deployment of the myogenic gene program. Alignment, elongation and fusion were grossly impaired in null cells, and myogenic gene expression was not coordinated with cytoskeletal and membrane remodeling events. Rescue studies and genome-wide analyses extended previous findings that a β-catenin-TCF/LEF interaction is not required for differentiation, and that β-catenin enhances MyoD binding to myogenic loci. We mapped cellular pathways controlled by β-catenin and defined novel targets in myoblasts, including the fusogenic genes myomaker and myomixer. We also showed that interaction of β-catenin with α-catenin was important for efficient differentiation. Overall the study suggests dual roles for β-catenin: a TCF/LEF-independent nuclear function that coordinates an extensive network of myogenic genes in cooperation with MyoD; and an α-catenin-dependent membrane function that helps control cell-cell interactions. β-Catenin-TCF/LEF complexes may function primarily in feedback regulation to control levels of β-catenin and thus prevent precocious/excessive myoblast fusion.
Implementation of shared decision-making in healthcare policy and practice: a complex adaptive systems perspective
Authors: Munro Sarah , Kornelsen Jude , Wilcox Elizabeth , Kaufman Sarah , Bansback Nick , Corbett Kitty , Janssen Patricia 
Published: January 2019

Background:Despite the suggested benefits of shared decision-making (SDM), its implementation in policy and practice has been slow and inconsistent. Use of complex adaptive systems (CAS) theory may provide understanding of how healthcare system factors influence implementation of SDM.
Methods:Using the example of choice of mode of birth after a previous caesarean section, in-depth, semi-structured interviews were conducted with patients, providers, and decision makers in British Columbia, Canada, to explore the system characteristics and processes that influence implementation of SDM. Implementation and knowledge translation principles guided study design, and constructionist grounded theory informed iterative data collection and analysis.
Findings:Analysis of interviews (n=58) revealed that patients formed early preferences for mode of delivery (after the primary caesarean) through careful deliberation of social risks and benefits. Physicians acted as information providers of clinical risks and benefits, while decision makers revealed concerns related to liability and patient safety. These concerns stemmed from perceptions of limited access to surgical resources, which had resulted from budget constraints.
Discussion and conclusions:To facilitate the effective implementation of SDM in policy and practice it may be critical to initiate SDM once patients become aware of their healthcare options, assist patients to address the social risks that influence their preferences, manage perceptions of risk related to patient safety and litigation among physicians, and enhance access to healthcare resources.
Evidence to support delivery of effective health services: a responsive programme of rapid evidence synthesis
Authors: Chambers Duncan , Booth Andrew , Rodgers Mark , Preston Louise , Dalton Jane , Goyder Elizabeth , Thomas Sian , Parker Gillian , Street Andrew , Eastwood Alison 
Published: January 2019

Background
Two UK academic centres were commissioned to provide a responsive rapid evidence synthesis service. The service covered topics identified by the National Institute for Health Research Health Services & Delivery Research (NIHR HSDR) programme as priorities for the National Health Service or to inform research commissioning.

Aims and objectives
To describe and evaluate the review teams’ interactions with the evidence users the programme aimed to serve, primarily NHS clinicians, commissioners and managers. We particularly aim to highlight the barriers and facilitators to the impact that this type of programme may have on the uptake and use of research evidence by decision makers.

Methods
Narrative review of stakeholder interactions at different stages of the review process: prioritisation and defining scope; dealing with unexpected results; dissemination of findings; and measuring impact, illustrated by examples from the first three years of the service (2014–17).

Conclusions
Timely production of high-quality outputs was facilitated by: initial mapping and scoping of the available published evidence; early engagement with stakeholders to optimise their involvement within limited time and resources; and willingness to consider creative solutions and different ways of working to overcome problems encountered in specific projects.
Prende la computadora, usa el diccionario de colocaciones de sustantivo + verbo y mejora tu aprendizaje
Authors: Jordan de Mogendorff Ivonne , Bevilacqua Cleci 
Published: January 2019

Este trabajo presenta una propuesta inicial de diccionario pedagógico bilingüe de colocaciones formadas por sustantivo + verbo en lengua española. Su objetivo es auxiliar a los alumnos de español, hablantes de portugués brasilero, en sus producciones orales y escritas. Estos estudiantes tienen dificultad especial con aquellas colocaciones en las que el verbo o el sustantivo es diferente en las dos lenguas como en “prender la computadora” (español) y “ligar o computador” (portugués) o “tener éxito” (español) y "ter sucesso" (portugués). Los estudiantes, generalmente no las trabajan de forma clara y explícita en los niveles iniciales de enseñanza, y por ese motivo, hacen la transferencia de su lengua materna para el español. Este trabajo aporta un panorama general sobre la Fraseología, deslinda su objeto de estudio y detalla las características de las colocaciones. Posteriormente, se expone la metodología que se emplea para la selección de las colocaciones y se presenta una propuesta de diccionario de colocaciones de sustantivo + verbo divergentes entre ambas lenguas. Se espera que este diccionario auxilie a los alumnos brasileros a mejorar su dominio colocacional y, por ende, su competencia comunicativa.
Beneficial effects of Spirogyra Neglecta Extract on antioxidant and anti-inflammatory factors in streptozotocin-induced diabetic rats
Authors: Mesbahzadeh Behzad , Rajaei Seyed Ali , Tarahomi Parnia , Seyedinia Seyed Ali , Rahmani Mehrnoush , Rezamohamadi Fatemeh , Kakar Muhammad Azam , Moradi-Kor Nasroallah 
Published: January 2019

AbstractObjectivesThis study was conducted to evaluate the effects of oral supplementation ofSpirogyraalgae on oxidative damages and inflammatory responses in streptozotocin (STZ)-induced diabetic rats.MethodsDiabetes was induced by administration of 55 mg/kg of streptozotocin. A total of sixty-four rats were divided into eight groups of eight rats each as follows:1) non-diabetic control; 2, 3, and 4) non-diabetic rats treated with 15, 30, and 45 mg ofSpirogyraalgae/kg/d; 5) control diabetic; and 6, 7, and 8) diabetic rats treated with 15, 30, and 45 mg ofSpirogyraalgae extract. At the end of the trial, the serum concentrations of glucose, interleukin-6 (IL-6), tumor necrosis factor-a (TNF-a), malondialdehyde (MDA), glutathione (GSH), total antioxidant status (TAS), C-reactive protein (CRP), insulin, triglycerides, and cholesterol were examined by specified procedures.ResultsOur findings indicated that the administration of STZ significantly increased the serum concentrations of glucose, triglycerides, cholesterol, CRP, IL-6, TNF-a, and MDA and decreased the serum levels of GSH and TAS (P<0.05) in diabetic rats. Oral administration ofSpirogyraalleviated adverse effects of diabetes on oxidative stress and inflammatory factors in diabetic rats (P<0.05).ConclusionIt can be stated thatSpirogyraalgae extract can be used for treatment of diabetes likely due to prevention of oxidative stress and alleviation of inflammation in the rat model.
Production and Analysis of Recycled Ammonium Perrhenate from CMSX-4 superalloys
Authors: Gonzalez-Rodriguez J. , Pepper Katherine , Baron M.G. , Mamo S.K. , Simons A.M. 
Published: January 2019

AbstractThe process to extract rhenium from a superalloy is an immense technical challenge due the complex chemistry involved. Being one of the rarest elements in the earth’s crust the scarcity and cost of rhenium makes it advantageous to recover the element from scrap superalloy. In this research the separation and monitoring of the different stages of the recycling process to extract rhenium from CMSX-4 superalloys using a distillation process were performed. This novel method combining distillation and use of exchange resins was used to separate rhenium from a complex mixture of metals in the CMSX-4 superalloy. The identification and quantitation of perrhenate and contaminants were performed by atomic absorption spectroscopy (AAS), Fourier transform infrared spectroscopy (FTIR), ion chromatography (IC) and Scanning Electron Microscopy- Energy Dispersive X-Ray (SEM-EDX). Perrhenate ions were extracted with purity close to 93%. The analytical characteristics for a novel infrared method to quickly identify perrhenate anions from CMSX-4 are presented. The main characteristics of the analytical validation were: LoD: 0.5% w/w; LoQ: 1.5% w/w; linear range 1.5-100% w/w; correlation coefficient R2 = 0.9905; precision (%RSD) for 10%w/w = 6.6 and 75%w/w = 4.1, respectively; accuracy (%) for 10% w/w 99.6% and 75% w/w=101.1, respectively.
Control of Integrating Process with Time Delay
Authors: Raza Ashraf , Anwar Nishat 
Published: January 2019

Abstract
This paper addresses the control of integrating processes with time delay. Two different control structures, namely single feedback loop (SFBL) and double feedback loop (DFBL) have been considered. In the SFBL, the controller has been designed using direct synthesis approach for the desired regulatory performance. In the DFBL, the inner loop controller is the proportional only controller which stabilizes the inner loop. The outer loop controller of DFBL has been designed through direct synthesis approach to achieve desired servo performance. Both the proposed control scheme works satisfactorily for low order as well as high order integrating process which may have a time delay and inverse response dynamics. Simulation of various examples shows improved performance when compared with the recently reported method.
A Design of the Beam-Adjustable Metasurface Based on the Plasma Metamaterial with the Dielectric Matching Layers
Authors: Zhang Hai-Feng , Ma Yu , Zhang Hao 
Published: January 2019

Abstract
In this paper, a beam-adjustable metasurface (BAM) is realized based on the plasma metamaterial with a dielectric matching layer technique, which is a novel phase compensation method. In order to realize phase compensation from 0° to 360°, the dielectric matching layers are added above the BAM to compensate the phase. The added dielectric layers can have different refractive indices or different thicknesses. Compared with the conventional phase compensation methods, such a method has an universal adaptability, and the phase curve of unit cell does not need to cover 0° ~ 360°. The elements of the BAM can be reconstructed by adjusting the excitation region of the plasma resonance structures to achieve spatial beam scanning. The simulation results show that the proposed BAM has a good performance. It provides that such a novel idea can help to design the novel BAMs to obtain the adjustable and scannable reflective beam in space.
Design of Balanced Filter with Wide Stopband by Using Discriminating Coupling
Authors: Cao Qingchun , Liu Hui , Gao Li 
Published: January 2019

Abstract
This paper presents a novel balanced filter with enhanced stopband by using discriminating coupling. The proposed design utilizes third-order quarter-wavelength coupled resonators to obtain the filtering responses. Discriminating coupling is applied between feedline and resonator. The circuit is theoretically analyzed and implemented for demonstration. The operating frequency is located at 2.4 GHz and the common-mode rejection is larger than 20 dB up to 9 GHz (3.75f0). Due to discriminating coupling, the differential mode out-of-band rejection is larger than 20 dB up to 18 GHz (7.5f0), which shows wide stopband.
Hydrogenation of Dibenzo-18-Crown-6 Ether Using γ-Al2O3 Supported Ru-Pd and Ru-Ni Bimetallic Nanoalloy Catalysts
Authors: Suryawanshi Yogeshwar R. , Chakraborty Mousumi , Jauhari Smita , Mukhopadhyay Sulekha , Shenoy Kalsanka. T. 
Published: January 2019

AbstractRuthenium-palladium (Ru-Pd) and ruthenium-nickel (Ru-Ni) bimetallic nanoalloy particles with various metal compositions were synthesized by microwave irradiated (MWI) solvothermal technique using PVP (poly-N-vinyl-2-pyrrolidone) as capping agent and ethylene glycol as a solvent as well as reducing agent. Synthesized bimetallic nanoalloy particles were subsequently impregenated onto γ-Al2O3support to obtain supported nanoalloy catalysts. Agglomeration of nanoalloyparticles were restricted by using excess solvent during synthesis, then distilled and recovered after completion of reaction. Hydrogenation of Dibenzo-18-crown-6 ether (DB18C6) was carried out at 9 MPa, 120°C and 3.5 h using synthesized bimetallic nanoalloy catalysts. It was observed that bimetallic nanolloycatalyst synthesized by MWI using Ru:Pd 3:1 % (w/w), exhibited higher catalytic activity and resulted 98.9 % conversion of DB18C6 with 100 % selectivity towards cis-syn-cis dicyclohexano-18-crown-6 ether (CSC DCH18C6).
A Multi-Objective Framework to Improve Voltage Stability in A Distribution Network
Authors: Aravinth Arputha , Vatul Vikas Anand , Narayanan K , Muthukumar K , Senjyu Tomonobu 
Published: January 2019

Abstract
This paper investigates the performance of a radial system while installing a Distributed Generator (DG) in existing Distribution Network (DN). The investigation has been performed with various types of DG units for different topologies of the DN. The present work uses a Voltage Stability Index (VSI) for identifying the location for installing a DG in the DN. A multi-objective framework is proposed to evaluate the size of the DG to be installed by reducing power loss and deviation in bus voltage. Genetic Algorithm (GA) is used to optimize the size of DG. The proposed method has been tested with different types of DG units on standard systems (IEEE-33 bus and IEEE-69) with different radial topologies of DN.
The TRAP-BATH split in RP: A linguistic index for English learners
Authors: Yang James H. 
Published: January 2019

Abstract
Received Pronunciation (RP) holds prestige not only in the UK, but also in many Outer and Expanding Circle countries and, even in the US, but the TRAP-BATH split (TBS) in RP, which refers to the shift from the vowel /a/ to /ɑː/, has still remained ambiguous because this sound shift contains inconsistent realizations that occur in identical codas, as illustrated in such lexical pairs as class but gas, path but math, last but enthusiast. What makes this sound feature more complicated is sociolinguistic variation. Although earlier discoveries have enhanced our understanding of the TBS, neither a definitive word list nor lexical frequency are provided for learners to enunciate BATH words. To provide RP learners with a linguistic index to learn BATH lexical set, this study expanded Wells’s study by including additional 16 phonetic environments, which generated a total of 304 relevant words for examining their pronunciation defined by dictionaries. The findings show that 13 out of the 30 environments can trigger the TBS more than 50% of the time. In particular, seven of them can completely predict the TBS (over 91%), and one of them can fully do so (83%). This feature appears as a regular conditioned sound pattern if well-defined by its phonetic environments.
The effects of a Melissa officinalis L. based product on metabolic parameters in patients with type 2 diabetes mellitus: A randomized double-blinded controlled clinical trial
Authors: Nayebi Neda , Esteghamati Alireza , Meysamie Alipasha , Khalili Nahid , Kamalinejad Mohammad , Emtiazy Majid , Hashempur Mohammad Hashem 
Published: January 2019

Abstract

Background
Diabetic patients are at increased risk for coronary artery disease. Since phytotherapy has been greatly common, finding safe and effective treatments is of importance. This study aimed to evaluate the effects of a Melissa officinalis L. based product (MO) in patients with type 2 diabetes.

Methods
A randomized double-blinded controlled study was conducted with 37 dyslipidemic diabetic patients, assigned to either MO or placebo (P) groups receiving two 500 mg capsules daily for 3 months. Finally, 32 cases completed the study and were included in the analysis; MO (n=16) and P (n=16).

Results
Safe and significant effects in terms of decreasing the serum level of triglyceride (TG) in all patients after 2 months (p-value=0.02) and in patients with higher baseline serum levels of TG (TG≥200 mg/dl) after 3 months (p-value=0.04) were shown in the MO group. However, no metabolic significant changes were seen compared to the control group. Significant decrease in both systolic and diastolic blood pressure from baseline values were also found in patients with higher systolic blood pressure (SBP≥130 mmHg) (p-value=0.02) and those with higher diastolic blood pressure (DBP≥85 mmHg) (p-value=0.02) in the MO group.

Conclusion
This study showed that MO might be safe and beneficial in decreasing the serum TG level in dyslipidemic diabetic patients. Although, larger long-term studies are required.