bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Pre‐emptive strike”—the case for early treatment of hepatic sinusoidal obstruction syndrome with defibrotide
Authors: Rajagopal Revathi , Phillips Marianne B. , Gottardo Nicholas G. 
Published: March 2018

AbstractThe initial signs of hepatic sinusoidal obstruction syndrome (HSOS) can be challenging to recognize in children, especially outside the hematopoietic stem cell transplantation setting. To assist clinicians to promptly identify HSOS, the European Society for Blood and Marrow Transplantation has proposed pediatric HSOS diagnostic criteria which emphasize unexplained consumptive and transfusion‐refractory thrombocytopenia. To highlight the importance of these “bellwether” early signs of HSOS and the efficacy of pre‐emptive treatment with defibrotide, we describe the case of a child with a right 11th rib primitive neuroectodermal tumor who developed HSOS following focal radiotherapy and actinomycin‐D treatment.
The promise of piezoelectric polymers
Authors: Usher Timothy D , Cousins Kimberley R , Zhang Renwu , Ducharme Stephen 
Published: March 2018

AbstractRecent advances provide new opportunities in the field of polymer piezoelectric materials. Piezoelectric materials provide unique insights to the fundamental understanding of the solid state. In addition, piezoelectric materials have a wide range of applications, representing billions of dollars of commercial applications. However, inorganic piezoelectric materials have limitations that polymer ferroelectric materials can overcome, if certain challenges can be addressed. This mini‐review is a practical summary of the current research and future directions in the investigation and application of piezoelectric materials with an emphasis on polymeric piezoelectric materials. We will assume that the reader is well versed in the subject of polymers, but not as familiar with piezoelectric materials. © 2018 Society of Chemical Industry
Flame retardant polycyanurate thermosets from the cyanate esters of triphenylphosphine oxide
Authors: Davis Matthew C. , Garrison Michael D. , Ghiassi Kamran B. , Groshens Thomas J. , Redeker Neil D. 
Published: March 2018

ABSTRACTThree cyanate esters containing phosphorus are synthesized in good overall yields starting from bromoanisoles. Di‐ and tricyanates with meta configuration are most stable while para is less so. The para dicyanate ester isomer is particularly affected by water from the atmosphere. The meta dicyanate ester 2 has good thermal properties with glass transition at 268 °C and char yield of 65% in air at 600 °C. All three phosphorus‐containing cyanate esters are low flammability in an open flame. They make highly combustible cyanate esters resins less flammable simply by blending. Mixing 10 wt% dicyanate ester 2 into bisphenol A or E dicyanate esters makes them rate V‐0. Published 2018.† J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 1100–1110
Water exercise in coronary artery disease patients, effects on heart rate variability, and body composition: A randomized controlled trial
Authors: Fiogbé Elie , Ferreira Rafaela , Sindorf Márcio Antônio Gonçalves , Tavares Silvia Aparecida , de Souza Keiti Passoni , de Castro Cesar Marcelo , Lopes Charles Ricardo , Moreno Marlene Aparecida 
Published: March 2018

AbstractBackground and PurposeIt is important to assess the effectiveness and efficiency of water‐based training programs in order to prescribe it as an alternative in cardiac rehabilitation for patients who have coronary artery disease (CAD). In these patients, autonomic dysfunction is an important physiological change strongly associated with adverse outcomes, morbidity, and mortality. Given that the beneficial effects of physical training in CAD patients have been traditionally evidenced with programs involving land‐based aerobic exercises, this study aims to evaluate the effects of water aerobic exercise training (WAET) on the autonomic modulation of heart rate (HR) and body composition, in the rehabilitation of CAD patients.MethodsTwenty‐six male subjects with CAD were randomly divided into a training group (n = 14), submitted to the WAET, and a control group (n = 12). The WAET consisted of 3 weekly sessions on alternate days, totalling 48 sessions. The analysis of HR variability was used to evaluate the autonomic modulation of HR, from the recording of R‐R intervals for 15 min, at rest in the supine position, and the body composition was evaluated through the bioelectrical impedance analysis.ResultsOnly the training group participants had improvement in the HR variability indices; patterns without variation decreased (0V, p = .005) and an increase of patterns of two different variations (p < .001), Shannon entropy (p = .02), and normalized conditional entropy (p = .03), whereas the control group had an increase of 0V (p = .04) and a decrease of normalized conditional entropy (p = .01). All body composition variables remained unchanged.ConclusionsThe WAET protocol improved the cardiac autonomic modulation of patients with CAD and can be considered as exercise training strategy in cardiac rehabilitation programs.
Molecular characterization and evolution of a chemosensory receptor gene family in three notorious rice planthoppers, Nilaparvata lugens, Sogatella furcifera and Laodelphax striatellus, based on genome and transcriptome analyses
Authors: He Peng , Engsontia Patamarerk , Chen Guang‐Lei , Yin Qian , Wang Jun , Lu Xu , Zhang Ya‐Nan , Li Zhao‐Qun , He Ming 
Published: March 2018

AbstractBACKGROUNDThe white‐backed planthopper (WBPH) Sogatella furcifera, the brown planthopper (BPH) Nilaparvata lugens, and the small brown planthopper (SBPH) Laodelphax striatellus (Hemiptera: Delphacidae) are rice pests that damage rice plants by sap‐sucking and by transmitting viruses. Host‐seeking behavior involves chemosensory receptor genes that include odorant receptors (ORs), ionotropic receptors (IRs) and gustatory receptors (GRs).RESULTSWe used genome and transcriptome data to identify 141 ORs, 28 GRs and 25 IRs in BPH; 135 ORs, 18 GRs and 16 IRs in WBPH; and 37 ORs, 14 GRs and 6 IRs in SBPH. A phylogenetic analysis identified several specific OR clades of rice planthoppers, the results indicating that these OR members might be used to respond to specific host volatiles. OR co‐receptor (Orco) is the most conserved and essential OR gene among these species and RNA interference (RNAi) can decrease their mRNA expression level to <50%. RNAi knockdown rice planthoppers were anosmia and were unable to seek or locate rice plants in behavioral tests.CONCLUSIONThe results demonstrate the importance of the planthopper Orco genes in locating rice plants. This information may aid in the development of RNAi‐based transgenic rice and other pest management technologies. © 2018 Society of Chemical Industry
Performance evaluation of EWMA and CUSUM control charts to detect anomalies in social networks using average and standard deviation of degree measures
Authors: Hosseini Seyed Soheil , Noorossana Rassoul 
Published: March 2018

AbstractDetection of communication outbreak among members of a network or a subgroup of a network has been a topic of interest in the literature of social network analysis. One approach to monitoring changes in a social network is to monitor graph measures related to the network representation in each period and detecting anomalies by applying a control chart. In this paper, we compare the performance of average degree and standard deviation of degree measures of a network for detecting outbreaks on a weighted undirected network using exponentially weighted moving average and cumulative sum control charts. Evaluation results indicate that average degree measure is better in detecting small changes than standard deviation of degree measure. Whereas for greater changes and outbreaks consisting of more members of the network, the opposite is true. In addition, exponentially weighted moving average control charts perform better than cumulative sum in detecting smaller changes and outbreaks consisting of less members of the network.
Cd(II) Pseudohalide Complexes with N, N′‐Bis(3‐ethoxysalicylidenimino) 1,3‐Diaminopropane: Crystal Structures, Hirshfeld Surface, Antibacterial and Anti‐Biofilm Properties
Authors: Majumdar Dhrubajyoti , Biswas Jayanta Kumar , Mondal Monojit , Babu Manabolu Surya Surendra , Das Sourav , Metre Ramesh K. , SreeKumar Sreejith S. , Bankura Kalipada , Mishra Dipankar 
Published: March 2018

AbstractSelf‐assemblies of N2O4 donor Schiff base ligands, that is, N,N′‐Bis(3‐ethoxysalicylidenimino) 1, 3‐diaminopropane (H2LOEt) with cadmium acetate salts in presence of auxiliary co‐ligands thiocyanato/azido/chloride allow the formation of three anion control complexes, specifically, [Cd2LOEt(μ1,3‐SCN)(η1‐SCN)]n (1), {Cd4(LOEt)2(μ1,1‐N3)3(η1‐N3)]2 (2) and [Cd2(LOEt)(Cl)2.CH3OH].CH3OH] (3). Crystal structures of complexes 1–3 were determined by single‐crystal X‐ray diffraction studies. The single‐crystal X‐ray diffraction analysis confirmed that complex 1 is an one‐dimensional polymeric chain in which Cd(II) ions are bridged by one thiocyanate group bonding in an end‐to‐end fashion. Complex 2 is a centrosymmetric octanuclear complex with double end‐on azide (μ1,1‐N3−) as linker. On the other hand, 3 is a dinuclear complex with terminally bound Cl− ions. Analysis of the structure revealed that all the complexes possess a 4‐membered Cd2 (μ2‐O)2 core fastened by the combined coordination action of a doubly deprotonated ligand. Complexes 1–3 have been successfully characterized by elemental analyses, IR and UV‐Vis spectroscopy. The luminescent properties of complexes 1–3 have been studied in DMSO solution. The antibacterial and antibiofilm potential for complexes 1–3 were investigated against Gram‐positive and Gram‐negative bacterial strains. Intermolecular interactions with respect to percentages of hydrogen bonding of cadmium complexes were quantified by Hirshfeld surface.
New Examples of Phase Control in the Preparation of Copper Sulfide Nanoparticles and Deposition of Thin Films by AACVD from Bis(piperidinedithiocarbamato)copper(II) Complex
Authors: Khan Malik D. , Akhtar Masood , Malik Mohammad A. , Revaprasadu Neerish , O'Brien Paul 
Published: March 2018

AbstractBis(piperidinedithiocarbamato)copper(II) was used as a precursor for the synthesis of copper sulfide nanoparticles in solutions of different compositions derived from: dodecanethiol (DT), oleylamine (OLA) and trioctylphosphine (TOP) which can be viewed as components acting as, solvents, surfactants or ligands. The powder‐X‐Ray diffraction of the nanoparticles showed predominately roxbyite, and/or djurleite phase based on the solvent mixture used, and covellite or dignite in OLA depending on the temperature. The morphology changed from spherical to hexagonal discs with variation of the solvent from DT to DT/TOP (2:1) mixture. Thin films of copper sulfide were also deposited by the Aerosol Assisted Chemical Vapour Deposition (AACVD). Djurleite was the only phase deposited by AACVD (350, 400 and 450 °C). Cubes, short rods and spherical microstructures were observed in the SEM images, with average size increasing with temperature.
Water‐Soluble Copper Complex Derived from Ligand TETATA Having NNN Donors: Studies on Rapid Degradation of Organic Dyes, Catecholase and Phenoxazinone Synthase Activities
Authors: Singh Ovender , Maji Ankur , Singh Udai P. , Ghosh Kaushik 
Published: March 2018

AbstractWater‐soluble copper complex [Cu(TETATA)(Cl2)] (1) derived from tridentate ligand (TETATA) (L=2‐(2‐((2‐((2‐aminoethyl)amino)ethyl)‐ amino)ethyl)isoindoline‐1,3‐dione) having NNN donor, was synthesized, characterized and its molecular structure was determined using X‐ray crystallography. This water soluble copper complex was found to be an efficient catalyst for rapid degradation of organic dyes like orange II, rhodamine B and methylene blue dyes were investigated. This catalyst was also utilised for the oxidation of catechol, giving rise to catecholase activity as well as oxidative coupling of 2‐aminophenol providing phenoxazinone synthase activity. DFT and TD‐DFT calculations were performed to understand the electronic properties of this molecule using B3LYP/LANL2DZ basis set.
Green Synthesis of 1,4‐Dihydropyridine Derivative in Water
Authors: Isomura Shigeki , Horigome Ami , Kubo Kotaro , Yoshizawa Yukari , Okuno Yoshinori , Okayasu Misaki , Azumaya Isao , Sato Yasuo 
Published: March 2018

AbstractA simple and environmentally clean synthesis of 4‐methoxycarbonylmethyl‐1,4‐dihydropyridine‐3,5‐dicarboxylic acid dimethyl ester was achieved by heating methyl propiolate with an amine salt in water. Excess amine salt accelerated the reaction in the case of aliphatic amines, while stoichiometric amounts of propiolate ester and amine salt resulted in low yield. In the case of aniline, a 1:3 ratio of amine salt and methyl propiolate afforded 77% yield in 24 h. The free amine is proposed to serve as nucleophile for Michael addition reaction, and the liberated proton acts as an electrophilic catalyst.
Impact of the Type of Reactor and the Catalytic Conditions on the Photocatalytic Production of Hydrogen Using a Fully Noble‐Metal‐Free System
Authors: Reim Immanuel , Wriedt Benjamin , Tastan Ümit , Ziegenbalg Dirk , Karnahl Michael 
Published: March 2018

AbstractFor efficient photocatalytic hydrogen production not only the photocatalytic system itself, but also the reactor design and appropriate catalytic conditions play a central role for achieving high overall activity and long lifetimes. To investigate these points further, a fully noble‐metal‐free system for the light‐driven reduction of protons to hydrogen, consisting of a copper photosensitizer and an iron carbonyl catalyst, was chosen as a model. The traditional batch reactor was replaced by a semi‐batch photoreactor with a continuously perfused gas phase in combination with in situ gas chromatography. This allowed for the time resolved analysis of all gases formed and enabled a systematic investigation of the impact of different light sources, light intensities and carrier gases. The results revealed a significant change in activity due to CO removal from the catalyst caused by the continuous gas flow. This effect can be counteracted by supplying additional CO through the gas phase.
Electrochemical Detection of Pseudomonas aeruginosa in Polymicrobial Environments
Authors: Santiveri Clara Romero , Sismaet Hunter J. , Kimani Martin , Goluch Edgar D. 
Published: March 2018

AbstractA major cause of hospital‐acquired infections is Pseudomonas aeruginosa, a gram‐negative bacterial pathogen. This bacterium secretes a unique, redox‐active molecule known as pyocyanin that can serve as a useful biomarker for identification and detection of this opportunistic pathogen. This current study investigates the impact to pyocyanin production and ability to electrochemically distinguish pyocyanin when P. aeruginosa is co‐cultured with other bacterial pathogens. To accomplish this, P. aeruginosa was co‐cultured with up to four different clinically‐relevant bacteria typically found in a wound infection. P. aeruginosa’s production of pyocyanin was electrochemically monitored over a three day period and the results demonstrated that pyocyanin can be readily measured and that there were no observed enhancements or inhibitory effects to the production of pyocyanin. This information is valuable in the development of this sensing platform for clinical point‐of‐care diagnostics, where polymicrobial growth at the site of infection is common.
Sandwich‐like MoS2@SnO2@C with High Capacity and Stability for Sodium/Potassium Ion Batteries
Authors: Chen Zhi , Yin Dangui , Zhang Ming 
Published: March 2018

AbstractSandwich‐like MoS2@SnO2@C nanosheets are prepared by facile hydrothermal reactions. SnO2 nanosheets can attach to exfoliated MoS2 nanosheets to prevent restacking of adjacent MoS2 nanosheets, and carbon transformed from polyvinylpyrrolidone is coated on MoS2@SnO2, forming a sandwich structure to maintain cycling stability. As an anode for sodium‐ion batteries, the electrode greatly deliverers a high initial discharge specific capacity of 530 mA h g−1 and maintains at 396 mA h g−1 after 150 cycles at 0.1 A g−1. Even at a large current density of 1 A g−1, it can hold 230 mA h g−1 after 450 cycles. Besides, as an anode for K+ storage, the electrode also shows a discharge capacity of 312 mA h g−1 after 25 cycles at 0.05 A g−1. This work may provide a new strategy to prepare other composites which can be applied to new kind of rechargeable batteries.
NiO as a Bifunctional Promoter for RuO2 toward Superior Overall Water Splitting
Authors: Liu Jinlong , Zheng Yao , Jiao Yan , Wang Zhenyu , Lu Zhouguang , Vasileff Anthony , Qiao Shi‐Zhang 
Published: March 2018

AbstractConventional development of nanomaterials for efficient electrocatalysis is largely based on performance‐oriented trial‐and‐error/iterative approaches, while a rational design approach at the atomic/molecular level is yet to be found. Here, inspired by a fundamental understanding of the mechanism for both oxygen and hydrogen evolution half reactions (OER/HER), a unique strategy is presented to engineer RuO2 for superior alkaline water electrolysis through coupling with NiO as an efficient bifunctional promoter. Benefitting from desired potential‐induced interfacial synergies, NiO‐derived NiOOH improves the oxygen binding energy of RuO2 for enhanced OER, and NiO also promotes water dissociation for enhanced HER on RuO2‐derived Ru. The resulting hybrid material exhibits remarkable bifunctional activities, affording 2.6 times higher OER activity than that of RuO2 and an HER activity comparable to Pt/C. As a result, the simple system requires only 1.5 V to deliver 10 mA cm−2 for overall alkaline water splitting, outperforming the benchmark PtC/NF||IrO2/NF couple with high mass loading. Comprehensive electrochemical investigation reveals the unique and critical role of NiO on the optimized RuO2/NiO interface for synergistically enhanced activities, which may be extended to broader (electro)catalytic systems.
Etching‐Assisted Crumpled Graphene Wrapped Spiky Iron Oxide Particles for High‐Performance Li‐Ion Hybrid Supercapacitor
Authors: Kim Eunji , Kim Hyeri , Park Byung‐Jun , Han Young‐Hee , Park Jong Hyuk , Cho Jinhan , Lee Sang‐Soo , Son Jeong Gon 
Published: March 2018

AbstractFrom graphene oxide wrapped iron oxide particles with etching/reduction process, high‐performance anode and cathode materials of lithium‐ion hybrid supercapacitors are obtained in the same process with different etching conditions, which consist of partially etched crumpled graphene (CG) wrapped spiky iron oxide particles (CG@SF) for a battery‐type anode, and fully etched CG for a capacitive‐type cathode. The CG is formed along the shape of spikily etched particles, resulting in high specific surface area and electrical conductivity, thus the CG‐based cathode exhibits remarkable capacitive performance of 210 F g−1 and excellent rate capabilities. The CG@SF can also be ideal anode materials owing to spiky and porous morphology of the particles and tightly attached crumpled graphene onto the spiky particles, which provides structural stability and low contact resistance during repetitive lithiation/delithiation processes. The CG@SF anode shows a particularly high capacitive performance of 1420 mAh g−1 after 270 cycles, continuously increases capacity beyond the 270th cycle, and also maintains a high capacity of 170 mAh g−1 at extremely high speeds of 100 C. The full‐cell exhibits a higher energy density up to 121 Wh kg−1 and maintains high energy density of 60.1 Wh kg−1 at 18.0 kW kg−1. This system could thus be a practical energy storage system to fill the gap between batteries and supercapacitors.
Model‐based systems engineering for life‐sciences instrumentation development
Authors: Patou François , Dimaki Maria , Maier Anja , Svendsen Winnie E. , Madsen Jan 
Published: March 2018

AbstractNext‐generation genome sequencing machines and Point‐of‐Care (PoC) in vitro diagnostics devices are precursors of an emerging class of Cyber‐Physical Systems (CPS), one that harnesses biomolecular‐scale mechanisms to enable novel “wet‐technology” applications in medicine, biotechnology, and environmental science. Although many such applications exist, testifying the importance of innovative life‐sciences instrumentation, recent events have highlighted the difficulties that designing organizations face in their attempt to guarantee safety, reliability, and performance of this special class of CPS. New regulations and increasing competition pressure innovators to rethink their design and engineering practices, and to better address the above challenges. The pace of innovation will be determined by how organizations manage to ensure the satisfaction of aforementioned constraints while also streamlining product development, maintaining high cost‐efficiency and shortening time‐to‐market. Model‐Based Systems Engineering provides a valuable framework for addressing these challenges. In this paper, we demonstrate that existing and readily available model‐based development frameworks can be adopted early in the life‐sciences instrumentation design process. Such frameworks are specifically helpful in describing and characterizing CPS including elements of a biological nature both at the architectural and performance level. We present the SysML model of a smartphone‐based PoC diagnostics system designed for detecting a particular molecular marker. By modeling components and behaviors spanning across the biological, physical‐nonbiological, and computational domains, we were able to characterize the important systemic relations involved in the specification of our system's Limit of Detection. Our results illustrate the suitability of such an approach and call for further work toward formalisms enabling the formal verification of systems including biomolecular components.
Factors Regulating Year‐Class Strength of Silver Carp Throughout the Mississippi River Basin
Authors: Sullivan Christopher J. , Weber Michael J. , Pierce Clay L. , Wahl David H. , Phelps Quinton E. , Camacho Carlos A. , Colombo Robert E. 
Published: March 2018

AbstractRecruitment of many fish populations is inherently highly variable interannually. However, this variability can be synchronous at broad geographic scales due to fish dispersal and climatic conditions. Herein, we investigated recruitment synchrony of Silver Carp Hypophthalmichthys molitrix across the Mississippi River basin. Year‐class strength (YCS) and synchrony of nine populations (maximum linear distance = 806.4 km) were indexed using catch‐curve residuals correlated between sites and related to local and regional climatic conditions. Overall, Silver Carp YCS was not synchronous among populations, suggesting that local environmental factors are more important determinants of YCS than large‐scale environmental factors. Variation in Silver Carp YCS was influenced by river base flow and discharge variability at each site, indicating that extended periods of static local discharge benefit YCS. Furthermore, river discharge and air temperature were correlated and synchronized among sites, but only similarities in river discharge were correlated with Silver Carp population synchrony, indicating that similarities in discharge (i.e., major flood) among sites can positively synchronize Silver Carp YCS. The positive correlation between Silver Carp YCS and river discharge synchrony suggests that regional flood regimes are an important force determining the degree of population synchrony among Mississippi River Silver Carp populations.