bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Sharing Mind Map-oriented Approach to Enhance Collaborative Mobile Learning With Digital Archiving Systems
Authors: Chang Jui-Hung , Chiu Po-Sheng , Huang Yueh-Min 
Published: February 2018

<p class="3">With the advances in mobile network technology, the use of portable devices and mobile networks for learning is not limited by time and space. Such use, in combination with appropriate learning strategies, can achieve a better effect. Despite the effectiveness of mobile learning, students’ learning direction, progress, and achievement may differ. Thus, the enhancement of learners’ opinions on the usability and interactivity during mobile learning are challenging issues to overcome. This study developed a sharing mind map-oriented mobile learning system integrated with valuable information preserved in a digital archiving system. In addition to the functions of traditional mind maps, this system also enabled students to complete and record relevant information that they had found onto the mind map and further improve the integrity of their own knowledge. To investigate the effectiveness of this teaching approach, this study added digital archive data and used mind map sharing to help learners develop knowledge. By using the proposed approach, students were able to perform self-assessment on learning content, choose appropriate learning directions, and progress according to their level of learning. At the same time, they could collaboratively learn with peers to engage themselves more deeply in their learning. That is, their learning motivation could be constantly triggered through the observations and sharing of mind maps from one to another. This study selected sixth graders as its research subjects in two classes at the school where one researcher works. There were 31 and 30 valid samples in the experimental group and control group, respectively, with a total of 61 students. The experimental group was conducted by using sharing mind map with corresponding geographical archived information to investigate the effectiveness of sharing mind map (SMM) in mobile learning; on the other hand, the control group was conducted by using a traditional learning approach. The outcomes indicate that students’ learning performance could be enhanced by using archived information SMM mobile learning.</p>
PENGEMBANGAN E-BOOK BERBASIS PROBLEM BASED LEARNING-GIS UNTUK MENINGKATKAN KECAKAPAN BERFIKIR KERUANGAN PADA SISWA KELAS X SMA N 1
Authors: Yusup Yasin , Santoso Sigit , Istifarida Binti 
Published: February 2018

<p class="Default">Tujuan dari penelitian ini adalah: (1) Mengidentifikasi kebutuhan bel­ajar siswa kelas X SMAN 1 Sragen 2016/2017, (2) menentukan kelayakan Pem­belajaran Soal Berbasis GIS (PBL-GIS) e-book yang dikembangkan di SMA N 1 Sragen tahun 2016/2017, (3) menentukan perbedaan kemampuan berpikir spasial sebelum dan sesudah menggunakan e-book PBL-GIS pada materi pelajaran Lithosfer di kelas X IPS SMA N 1 Sragen 2016/2017. Penelitian ini merupakan penelitian dan pengembangan (R &amp; D). Tahapan R &amp; D yang digunakan dalam penelitian ini adalah model ADDIE (Analysis, Design, Development, Implementa­tion, Evaluation). Hasil penelitian menunjuk­kan: (1) kebutuhan siswa dalam proses pembelajaran antar media lain yang dikemas dengan kreatif dan tidak monoton dalam teks, namun perlu ditambahkan video, begitu pula penggunaan model pembelajaran outdoor bagi siswa untuk segera kenali kejadian yang terjadi di sekitarnya; (2) hasil validasi tim ahli menunjukkan nilai rata-rata 73,2% termasuk dalam kriteria yang memenuhi syarat. Uji coba tanggapan siswa menunjukkan respon positif dengan persentase 83,2% termasuk kriteria yang san­gat layak; (3) perhitungan efektivitas media pembelajaran menggunakan t-test dan hasil tarithmetic = 10,244&gt; ttabel = 1,67. Ini berarti hipotesis penelitian diterima atau dengan kata lain, ada perbedaan yang signifikan antara kemampuan berpikir spasial siswa sebe­lum dan sesudah menggunakan buku berbasis PBL-GIS dalam materi pelajaran litosfer di kelas X IPS SMAN 1 Sragen. di tahun 2016/2017.</p><p class="Default"> </p><p class="Default">Kata kunci: metode penelitian dan pengembangan, e-Book Problem Based Learning-GIS, Keterampilan Berpikir Spasial, Litosfer.</p><p class="Default"> </p>
CHEMICAL COMPOSITIONS AND BIOLOGICAL PROPERTIES OF ESSENTIAL OILS FROM ZANTHOXYLUM RHETSA (ROXB.) DC AND ZANTHOXYLUM LIMONELLA ALSTON
Authors: Wongkattiya Nalin , Akekawatchai Chareeporn , Sanguansermsri Phanchana , Fraser Ian Hamilton , Pratoomsoot Chayanin , Sanguansermsr Donruedee 
Published: February 2018

Background: Zanthoxylum rhetsa (Roxb.) DC and Zanthoxylum limonella Alston are spices for flavouring in indigenous Thai food. They are traditionally used as an aromatic, astringent, antimicrobial, antiseptic and antidiabetic agent. The purpose of this study is to examine their chemical compositions and evaluate antibacterial, antioxidant and anticancer properties of the essential oils.
Materials and Methods: The essential oils of Z. rhetsa and Z. limonella were analysed for phytochemical constituents by Gas chromatography–mass spectrometry (GC-MS). The antibacterial activity was determined against several bacteria using the microdilution method. Antioxidant capacity was determined by free radical scavenger 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2-azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) methods. The anticancer activity was determined with two breast cancer cell lines (MCF-7 and MDA-MB-231) and the normal African green monkey kidney epithelial (Vero) cell line and using MTT assay.
Results: Sabinene (22.51%) and terpinene-4-ol (32.33%) were found to be major components of Z. rhetsa essential oil while limonene (57.94%) and alpha-phelladrene (15.54%) were the major components of Z. limonella essential oil. Essential oil from Z. limonella exhibited broad spectrum antibacterial activity. Z. rhetsa and Z. limonella essential oils exhibited moderate antioxidant activity. The essential oil from Z. rhetsa possessed the ability to inhibit breast cancer cell (MCF-7 and MDA-MB-231) proliferation and cell viability.
Conclusion: This study suggest that the essential oils from Z. limonella and Z. rhetsa could be applied as safe antibacterial and antioxidant agents for food and have the potential for further development of new anticancer agents.
IN VITRO ANTI-INFLAMMATORY ACTIVITY OF THE COMPONENTS OF AMOMUM TSAO-KO IN MURINE MACROPHAGE RAW 264.7 CELLS
Authors: Choi Chun Whan , Shin Ju Young , Seo Changon , Hong Seong Su , Ahn Eun-Kyung , Jung Young Hoon , Oh Joa Sub 
Published: February 2018

Background: Plants still remain the prime source of drugs for the treatment of inflammation and can provide leads for the development of novel anti-inflammatory agents.
Material and methods: An in vitro bioassay guide revealed that the 80% ethanol (EtOH) extract of the whole plant, Amomum tsao-ko (Zingiberaceae), displayed anti-inflammatory activity after assessing its effects on murine macrophage RAW 264.7 cells.
Result: Phytochemical study of the 80% EtOH extract of Amomum tsao-ko led to the isolation of eight compounds: 4-hydroxy-3-methoxy-benzoic acid (1), meso-hannokinol (2), (+)-hannokinol (3), coumaric acid (4), 4-hydroxy-benzoic acid (5), (+)-epicatechin (6), (-)-catechin (7), and myrciaphenone A (8). The results indicated that two of the isolated components, (+)-epicatechin (6) and (-)-catechin (7), inhibited the production of nitric oxide (NO) significantly in lipopolysaccharide treated RAW 264.7 cells.
Conclusion: LPS-induced interleukin tumor necrosis factor-alpha (TNF-), IL-1β and IL-10 production was also decreased in a dose-dependent manner. In addition, western blot analysis revealed that (+)-epicatechin (6) and (-)-catechin (7) reduced the expression of inducible nitric oxide synthase and inhibited nuclear localization of nuclear factor kappa-B (NF-κB).
HEPATOPROTECTIVE ACTIVITY OF COSTUS SPECIOSUS (KOEN. EX. RETZ.) AGAINST PARACETAMOL-INDUCED LIVER INJURY IN MICE
Authors: AlSaadi Baiaan H. , AlHarbi Shoaa H. , Ibrahim Sabrin R. M. , El-Kholy Amal A. , El-Agamy Dina S. , Mohamed Gamal A. 
Published: February 2018

Background: Liver diseases are a common cause of mortality and morbidity over the world. It is caused mainly by toxic chemicals and chemotherapeutic agents. Costus speciosus (Koen ex. Retz.) (Zingiberaceae) is widely employed in various traditional medicines for the prevention and treatment of different aliments. The purpose of this study is to assess the protective effect of C. speciosus rhizomes MeOH extract against the injury of the liver induced by paracetamol (PA) in mice.
Material and Methods: The mice were pretreated for seven days with distilled H2O, silymarin 12 mg/kg or 100 and 200 mg/kg MeOH extract. Then, PA (750 mg/kg) was also intra-peritoneal administrated once a day. Animals were euthanatized 24 h after the damage inducement. The levels of the serum enzymes aspartate aminotransferase (AST), alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate aminotransferase, in addition to the tumor necrosis factor-alpha (TNF-α), were determined. Moreover, the histopathological examination was carried out.
Results: Administration of the MeOH extract (200 mg/kg) showed improvement in the toxic effects of PA through significant fall on the serum markers enzymes of liver damage: AST, ALT, and ALP, as well as TNF-α, compared to silymarin. In parallel, the histopathological profile in the mice` liver also proved that extract markedly minimized the PA toxicity and maintained the liver tissues` histoarchitecture to near the normal ones more than that achieved by silymarin.
Conclusion: The findings suggested that C. speciosus extract acts as a potential hepatoprotective agent against PA-induced liver toxicity. This hepato-protection effect may be due to the existence of steroids, saponins, different glycosides, and phenolic compounds in C. speciosus.
Tardive dyskinesia and dexmedetomidine
Authors: Palmer James 
Published: February 2018

SummaryA 52‐year‐old female patient presented for a caudal epidurogram and epidural steroid injection. Patient compliance was limited by severe tardive dyskinesia secondary to previous chlorpromazine treatment. Based on a report of effectiveness in propofol‐induced dyskinesias, an infusion of dexmedetomidine was used which effectively controlled the movements within a few minutes. The patient remained alert and comfortable throughout. This report highlights the pharmacology and clinical application of dexmedetomidine in this clinical scenario, and proposes potential mechanisms underlying this therapeutic effect.
A GESTÃO DO EQUIPAMENTOS DE PROTEÇÃO INDIVIDUAL NA SEGURANÇA COMPORTAMENTAL
Authors: Velloso de Souza Gustavo Augusto , Braga Enilson , Arvellos Luis , De Carvalho José Thomaz 
Published: February 2018

Resumo: Este trabalho buscou apresentar os equipamentos de proteção individual (EPI) na construção civil, onde a utilização do mesmo torna-se necessária cada vez mais para a saúde e segurança dos trabalhadores. A obrigatoriedade das empresas no cumprimento das leis relativas à Segurança e Medicina no Trabalho, trouxe preocupação em evitar acidentes ou doenças ocupacionais. As inovações tecnológicas e a disseminação de informações sobre prevenção destes riscos tornam-se decisivas para melhorar a qualidade de vida no ambiente de trabalho.Neste artigo foi apresentado os equipamentos de proteção individual (EPI) que podem neutralizar ou minimizar as doenças ocupacionais ou até mesmo evitar as lesões decorrentes dos acidentes. O estudo visa, a abordagem preventiva, onde os profissionais envolvidos na construção civil devem atuar de forma consciente, no que se refere a segurança no trabalho. Para que tal conscientização ocorra se faz necessário levar até profissionais treinamento e capacitação. O objetivo deste trabalho é obter conhecimento, por meio de revisão bibliográfica, no ambiente de trabalho na área da construção civil para que possa ser minimizado o risco de acidentes no trabalho, levando aos futuros leitores o conhecimento necessário dos equipamentos de proteção individual (EPI) no ambiente da construção civil. Desta forma foi desenvolver prevenção em relação aos acidentes, por meio da segurança comportamental através do 5S. Palavras-chave: normas regulamentadoras, segurança do trabalho, EPI, trabalho em altura e 5S.
Erythrocyte Associated Amyloid-β as Potential Biomarker to Diagnose Dementia
Authors: Lauriola Michele , Paroni Giulia , Ciccone Filomena , D`Onofrio Grazia , Cascavilla Leandro , Paris Francesco , Gravina Carolina , Urbano Maria , Seripa Davide , Greco Antonio 
Published: February 2018

Background:
Although it is known that Alzheimer's disease (AD) is associated with the progressive
accumulation of amyloid β-peptide (Aβ) in the human brain, its pathogenic role has to be completely
clarified. Aβ moves from the bloodbrain barrier to the plasma and an increased Aβ production in
brain could be associated with higher Aβ concentrations in blood. A recent study has evaluated Aβ40
and Aβ42 levels in human red blood cells (RBCs) with evidence of agedependent higher Aβ concentration
in RBCs.

Objective:
The aim of the study was to investigate if erythrocyte associated Aβ (iAβ) levels could be
different in subjects affected by dementia in comparison with controls and according to the patient’s
cognitive impairment or different dementia subtypes.

Method:
To answer these questions we assessed iAβ40 and iAβ42 levels in 116 patients: 32 healthy
controls, 39 with diagnosis of vascular dementia (VaD), 14 mild cognitive impairment (MCI) and 31
AD.

Results:
In this population we found significant differences in iAβ42 between controls and cognitive
impaired patients. Moreover, iAβ42 significantly differed between dementia vs MCI. AD also showed
different iAβ42 levels as compared to VaD. Conversely, no differences were found for iAβ40. All the
analyses were adjusted for potential confounders like age, gender and Hb concentration. A direct correlation
between increasing iAβ42 concentration and the progression of the cognitive decline using the
MMSE score as continuous variable was also found.

Conclusion:
Our findings support the evidence that iAβ42 could be an instrument to early recognize
dementia and predict cognitive impairment.
A Laminated Ring on Elastic Foundation Model and a Feedback Contact Algorithm for Tire-Road Contact Analysis
Authors: Wang Chunjian , Ayalew Beshah , Rhyne Timothy , Cron Steve , Adcox John 
Published: February 2018

ABSTRACTThis article proposes (1) a two-dimensional tire model that extends the deformable ring on elastic foundation (REF) model by treating the ring as a laminated beam and (2) a feedback compensation approach to solve the tire-road contact problem as facilitated by the laminated REF model. The internal layer of the laminated ring is formulated using the Timoshenko beam theory that can also be easily regressed to an Euler beam. The external layer of the laminated ring is modeled as a circular beam that primarily takes into account the strain energy contributed by the tire tread in the transverse or radial direction. The elastic foundations are assumed to have a predeformation in the radial direction, which can model tire inflation pressure in pneumatic tires or foundation precompression/pretension for nonpneumatic tires. The analytical solution for the static deformation response of this laminated REF model due to an arbitrary external force is detailed first. Then, a feedback p-controller algorithm that penalizes geometry errors in the contact region is outlined as a unified approach that can be used to solve frictionless contact problems between a tire and arbitrary road profiles. The performances of the proposed model and algorithm are compared against those obtained from a detailed finite element analysis. Both flat surface and cleat contact responses are shown to illustrate the utility of this laminated REF model and the contact algorithm.
Are You Sure You Have a Strategy
Authors: Kholid Arif Rozaq Muhammad 
Published: February 2018

Tujuan tulisan ini adalah untuk mendiskusikan alternatif dalam prosesformulasi strategi. Seniman dalam menghadapi era industri kreatif tentunya membutuhkan strategi tertentu. terutama konsep dasar dalam formulasi strategi pada tingkat strategi bisnis, khususnya dalam industri kreatif. Telaah literatur menitikberatkan pada pendekatan strategi, apakah menggunakan strategi darurat (emergent strategy) atau strategi yang terartikulasi (deliberate strategy), atau campuran keduanya. Tulisan menawarkan salah satu pendekatan formulasi yang dikemukakan oleh Hambrick dan Fredrickson, 2001 yang dikenal dengan istilah Strategic Diamonds. Sebuah simpulan mengindikasikan bahwa Strategic Diamonds (Hambrick, 2001) sangat berguna dalam mengindentifikasi apa sebenarnya yang menjadi inti dari sebuah strategi. Elemen-elemen dari Strategic Diamonds dapat dipertimbangkan sebagai “penghubung” atau “titik pusat” dalam merancang sebuah sistem yang komprehensif dan terintegrasi. Tulisan ini mengusulkan kepada pelaku bisnis atau seniman untuk engartikulasikan strategi secara jelas (deliberate view), dan mengikuti Lima Elemen yang dikenal dengan Strategic Diamonds: arena, vehicles, differentiators, staging and economic logic sebagai inti dari penyusun sebuah strategi.
Gerak Tari Baris Tunggal dalam Fotografi Ekspresi Menggunakan Teknik Strobo Light
Authors: Yana* Ida Bagus Candra 
Published: February 2018

Dance photography is a photo shoot on a dance movement which has a characteristic as it shows on a particular movement with unique costumes. The arts of dance photography specifically describes through a specific thematic effect with an aesthetic and creative oncoming. Based on the photographer experience to capture the light together with his aesthetic expression on movement photography, he finally presented the visual arts on Baris Tunggal Dance in art photography expressions using strobe light. Basically, the creative works focused on the dancer movements and transformed into photography expression which blended with aesthetic and creative idea (ideational) also the technical photo shoot capability (technical) of the photographer. The photo shoots technique chosen through a variety of consideration which oriented on practical implementations possibilities, resulting photographs in freeze, blurred, and multiple-images as art photography. The art photograph includes extrinsic and intrinsic aesthetic values through photo presentation. With the presence of this photography art works it was not only present Gerak Tari Baris Tunggal dalam Fotografi Ekspresi Menggunakan Teknik Strobo Light in the form of mere documentation but it was the art photography expression on creative and aesthetic level. Keywords: movements, Baris Tunggal Dance, photography expression, strobo-light * Dosen ISI Denpasar
NOVEL GADIS PANTAI KARYA PRAMOEDYA ANANTA TOER SEBAGAI DASAR PENCIPTAAN SKENARIO
Authors: Wibowo Philipus Nugroho Hari 
Published: February 2018

Penciptaan ini mengadaptasi novel Gadis Pantai karya Pramoedya Ananta Toer (Pram) menjadi skenario. Kepiawaian Pram dalam menulis novel tidak diragukan lagi. Banyak karya Pram yang menjadi best seller, dari tangannya lahir karya-karya yang hebat, berbagai penghargaan pernah ia dapatkan, hingga nominasi nobel. Karya Pram sampai saat ini belum ada yang berhasil difilmkan, mungkin masa lalu Pram yang dekat dengan Lekra yang membuat seperti ini. Ide menjadi hal yang paling penting dalam sebuah skenario (film), Ide mengadaptasi novel menjadi pilihan yang jitu. Mengingat banyak film yang memenangkan penghargaan merupakan film adaptasi dari novel-novel best seler.Gadis Pantai Pramoedya Ananta Toer’s Novel as a Basic Scenario Creation. The creation is adapting the novel Gadis Pantai by Pramoedya Ananta Toer into a scenario. There is no doubt about Pram expertise in writing novels, many works of Pram considered as best seller, many great works were born from his hands, he has received the various awards, moreover, he was nominated as a nobel nominee. To this moment, there is no such works of Pram which is successfully filmed,it is probably because in his past time, Pram has been considered as a person who is “near” to LEKRA. An idea becomes the most important thing in making a screenplay (movie), The idea of adapting the novel becomes a workable option. As there have been many films that are also adaptated from the best seller novels.
ESTETIKA FOTOGRAFI JURNALISTIK DALAM KAITAN NILAI KEBAIKAN DAN KEBENARAN, OLAH RASA, DAN SINESTESIA
Authors: Andrea Novan Jemmi 
Published: February 2018

Fotografi jurnalistik menjadi salah satu cabang dari pengelompokan besar di bidang fotografi, selain fotografi seni dan fotografi komersial. Sebagai salah satu bidang seni, fotografi jurnalistik tentunya memiliki konsep estetika tersendiri, bahkan konsep estetikanya sangat berkaitan dengan “rasa”, sebuah konsep abstrak mengenai proses peresapan sesuatu dalam diri manusia yang bahkan tidak dapat sepenuhnya dideskripsikan. Pemahaman konsep estetika merupakan proses dialektis berkaitan dengan persoalan lain seperti filsafat, sosial, politik, budaya, dan ekonomi sehingga nilai-nilai kebaikan dan kebenaran sering muncul dalam ragam diskusi estetika. Perkembangan pendekatan konsep proses penciptaan yang melibatkan penonton dan berupaya menyajikan berbagai rangsangan bagi pancaindera menuntut kemampuan dalam olah rasa lainnya, yaitu mengoneksikan pancaindera. Konsep yang berkaitan dengan hal tersebut dikenal dengan istilah synaesthesia (sinestesia), sebuah konsep di mana pancaindera bekerja bersama sekaligus saat merespons sebuah rangsangan sehingga akan menimbulkan sensasi yang melebihi ungkapan satu pancaindera saja. Pemahaman estetika dengan berbagai pendekatan tersebut merupakan proses apresiasi aktif yang bertujuan untuk mengungkap kemungkinan-kemungkinan pewacanaan baru dalam perkembangan fotografi jurnalistik. Photojournalism Aesthetic in Regards to the Value of Goodness and Truth, Feeling , and Synaesthesia. Photojournalism becomes one of the branches of a large group in the field of photography in addition to art photography and commercial photography. Great photojournalism is a strange sort of art. Photojournalism allows people to get close to events on the ground, so that people may better understand them as they unfold. This is an abstract concept about the impregnation which cannot be fully described. Understanding the concept of aesthetics is a dialectical process associated with other problems such as philosophy, social, political, cultural, and economic so that the values of goodness and truth often comes in a variety of aesthetic discussion. Developments in the approach to the concept and creation process that involves the audience and trying to present a wide range of stimuli for the senses require proficiency in another sense though, that connected the all senses. Concepts related to the case known as synaesthesia, a neurological phenomenon in which one or more sensory modalities are linked. Aesthetic understanding of the various approaches is an active appreciation process that aims to uncover the possibilities of a new discourse on development of photojournalism.