bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERBEDAAN HASIL BELAJAR IPA BIOLOGI MENGGUNAKAN MODEL PEMBELAJARAN KOOPERATIF TIPE TEAM ASSISTED INDIVIDUALIZATION DENGAN TIPE MIND MAPPING PADA SISWA KELAS VII SMP NEGERI 19 MATARAM
Authors: Setiya Ningrum Arilda , Lestari Nur , Kusmiyati Kusmiyati 
Published: April 2018

Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar IPA Biologi pada siswa kelas VII menggunakan model pembelajaran tipe Team Asissted Indovidualization (TAI) dengan model pembelajaran Mind Mapping di SMPN 19 Mataram tahun ajaran 2017/2018. Jenis penelitian ini adalah penelitian komparatif. Desain penelitian yang digunakan adalah pretest-postest non-control group design. Populasinya adalah seluruh kelas VII SMP Negeri 19 Mataram. Penentuan sampel dilakukan dengan teknik simple random sampling dan diperoleh kelas VII C sebagai kelas eksperimen I dan kelas VII D sebagai kelas eksperimen II. Instrumen yang digunakan untuk mengukur hasil belajar adalah tes objektif dan tes subjektif untuk hasil belajar kognitif, lembar observasi siswa untuk hasil belajar afektif dan psikomotorik. Data yang diperoleh dianalisis dengan uji-t polled varians dengan taraf signifikansi 5%. Data yang diuji dengan uji-t adalah data gain score. Hasil uji-t untuk data hasil belajar kognitif didapatkan bahwa thitung > ttabel yakni 2,16 > 1,99. Hasil analisis data menunjukkan terdapat perbedaan hasil belajar siswa menggunakan model pembelajaran Team Assisted Individualization (TAI) dengan model pembelajaran Mind Mapping di SMP Negeri 19 Mataram tahun ajaran 2017/2018.ÃÂ This research aimed to determine the difference of science biology learning outcomes in VII grade students through the application of Team Assisted Individualization (TAI) learning model with Mind Mapping learning model at SMPN 19 Mataram academic year 2017/2018. The type of research was a comparative research. Pretest-posttest non-control group design was used as the design of this research. The population is the entire class VII SMP Negeri 19 Mataram. Samples were determined by simple random sampling technique that has chosen VII C as experiment class I and VII D as experiment class II. Objective and subjective tests were used to measure student achievement for cognitive student achievement, student observation sheets for effective and psychomotor student achievement. The data obtained were analyzed by t-test polled variance with a significance level of 5 %. The data tested by the t-test is the gain score data. Result of t-test for cognitive learning has found tcount ÃÂ > ÃÂ ttable that 2,16 > 1,99. The data analysis showed a difference in student learning result using TAI learning model with Mind Mapping learning model at SMP Negeri 19 Mataram academic year 2017/2018.
Hubungan Pengetahuan Ibu Tentang Pemberian Makanan Bayi dan Anak (PMBA) dengan Status Gizi Bayi Bawah Dua Tahun (Baduta)
Authors: Sari Fatimah , Ernawati Evy 
Published: April 2018

Background: The paradigm of the first 1000 days of life is the period of conception and giving opportunities in saving the lives and future of children. Breast milk is recommended as one of the exclusive source of nutrition in the first 6 months. Nutrition deficiency is suspected due to a lack of understanding of parents on proper nutritious food or due to the influence of advertising. They want to break the cycle of malnutrition that causes stunting.
Objective: This research aims to know the relationship of the level of knowledge of the feeding of infants and children (PMBA) with the nutritional status of infants under two years (BADUTA).
Method: This research is using descriptive analytic method with cross-sectional approach. Research subjects were mothers who had Baduta in the village of Pandes Wedi Klaten Regency in Central Java. The way of determining the sample by the total sampling techniques. Instrument research using questionnaires conducted test validity and reabilitas. Analysis of data for the purpose of hypothesis testing using statistical tests Spearman Rho.
Result: Mothers with good level of knowledge in feeding on baduta were as much as 100%. Whilst Baduta with good nutritional status were as much as 66.67%. Nutritional status of less baduta that is as much as 10 (33.33%). The results obtained bivariat relationship level of knowledge of mothers with nutritional Status Baduta the value of p = 0,272, since the p value > 0.05 (0,272 > 0.05) it can be stated there was no relationship between the level of knowledge of parents against the nutritional status of infants under two years of age.
Conclusion: There is no relationship of the level of knowledge with nutritional status baduta with a value of p = 0.272.
Ekstraksi Tanin pada Daun Ketapang (Terminalia Catappa L) dengan Variasi Pelarut, Konsentrasi Pelarut dan Lama Waktu Ekstraksi
Authors: Dhora Anna 
Published: April 2018

Tanaman ketapang (Terminalia catappa L) termasuk jenis tanaman yang sangat mudah tumbuh dan terdapat hampir di sebagian besar wilayah Indonesia. Selama ini pemanfaatan tanaman ketapang lebih banyak sebagai tanaman peneduh jalan. Dalam ketapang terkandung zat tanin yang setelah diekstrak dapat dimanfaatkan lebih lanjut. Tanin merupakan salah satu zat yang terdapat dalam tumbuhan dan memiliki banyak manfaat. Adanya tannin dalam beberapa bagian dari tumbuhan, memberikan manfaat tersendiri salah satunya sebagai pelindung bagi tumbuhan tersebut. Manfaat tanin antara lain dipakai dalam industri farmasi, industri pengolahan kulit, industri minuman dan industri pembuatan tinta. Tujuan secara umum yang diinginkan dari dilaksanakannya penelitian ini adalah meningkatkan nilai ekonomis dari tanaman ketapang, serta mengetahui variabel pemakaian pelarut dan waktu ekstraksi yang digunakan agar memberikan kemampuan maksimal untuk mengekstrak tanin dari daun ketapang. Metode yang diterapkan adalah metode sokletasi pada proses ekstraksi dan metode volumetri untuk proses analisa. Pelarut yang digunakan adalah etanol dan metanol yang dikombinasikan dengan aquadest, dengan lama waktu operasi ekstraksi 3 dan 4 jam. Dari penelitian yang telah dilakukan diketahui bahwa pemakaian pelarut metanol dan air dengan perbandingan 6 : 4 dengan waktu ekstraksi 4 jam, menghasilkan kadar tanin tertinggi sebesar 28,90 %. Sedangkan pada pemakaian pelarut campuran etanol dan air, menghasilkan kadar tanin tertinggi pada perbandingan 6 : 4 pada waktu ekstraksi 4 jam dengan kadar tanin 37, 17.Kata kunci: ketapang, tanin, etanol, metanol sokletasi
Involvement of the Spinal Cord in Mitochondrial Disorders
Authors: Finsterer Josef , Zarrouk-Mahjoub Sinda 
Published: April 2018

ABSTRACTThis review aims at summarising and discussing the current status concerning the clinical presentation, pathogenesis, diagnosis, and treatment of spinal cord affection in mitochondrial disorders (MIDs). A literature search using the database Pubmed was carried out by application of appropriate search terms and their combinations. Involvement of the spinal cord in MIDs is more frequent than anticipated. It occurs in specific and non-specific MIDs. Among the specific MIDs it has been most frequently described in LBSL, LS, MERRF, KSS, IOSCA, MIRAS, and PCH and only rarely in MELAS, CPEO, and LHON. Clinically, spinal cord involvement manifests as monoparesis, paraparesis, quadruparesis, sensory disturbances, hypotonia, spasticity, urinary or defecation dysfunction, spinal column deformities, or as transverse syndrome. Diagnosing spinal cord involvement in MIDs requires a thoroughly taken history, clinical exam, and imaging studies. Additionally, transcranial magnetic stimulation, somato-sensory-evoked potentials, and cerebrospinal fluid can be supportive. Treatment is generally not at variance compared to the underlying MID but occasionally surgical stabilisation of the spinal column may be necessary. It is concluded that spinal cord involvement in MIDs is more frequent than anticipated but may be missed if cerebral manifestations prevail. Spinal cord involvement in MIDs may strongly determine the mobility of these patients.
Practical consensus recommendations on Her2 +ve breast cancer with solitary brain mets
Authors: Rohatgi Nitesh , Munshi A. , Bajpai P. , Singh M. , Sahai S. , Ahmad M. , Singh K. , Singh H. , Parikh Purvish M. , Aggarwal S. 
Published: April 2018

AbstractBreast cancer is a common cause of brain metastases, with metastases occurring in at least 10–16% of patients. Longer survival of patients with metastatic breast cancer and the use of better imaging techniques are associated with an increased incidence of brain metastases. Current therapies include surgery, whole-brain radiation therapy, stereotactic radiosurgery, chemotherapy and targeted therapies. However, the timing and appropriate use of these therapies is controversial and careful patient selection by using available prognostic tools is extremely important. Expert oncologist discussed on the mode of treatment to extend the OS and improve the quality of life ofHER2-positivebreast cancer patients with Solitary brain metastases. This expert group used data from published literature, practical experience and opinion of a large group of academic oncologists to arrive at this practical consensus recommendations for the benefit of community oncologists.
The regional climate model REMO (v2015) coupled with the 1-D freshwater lake model FLake (v1): Fenno-Scandinavian climate and lakes
Authors: Pietikäinen Joni-Pekka , Markkanen Tiina , Sieck Kevin , Jacob Daniela , Korhonen Johanna , Räisänen Petri , Gao Yao , Ahola Jaakko , Korhonen Hannele , Laaksonen Ari , Kaurola Jussi 
Published: April 2018

Abstract. The regional climate model REMO was coupled with the FLake lake model to include an interactive treatment of lakes. Using this new version, the Fenno-Scandinavian climate and lake characteristics were studied in a set of 35-year hindcast simulations. Additionally, sensitivity tests related to the parameterization of snow albedo were conducted. Our results show that overall the new model version improves the representation of the Fenno-Scandinavian climate in terms of 2 m temperature and precipitation, but the downside is that an existing wintertime cold bias in the model is enhanced. The lake surface water temperature, ice depth and ice season length were analyzed in detail for 10 Finnish, 4 Swedish and 2 Russian lakes and 1 Estonian lake. The results show that the model can reproduce these characteristics with reasonably high accuracy. The cold bias during winter causes overestimation of ice layer thickness, for example, at several of the studied lakes, but overall the values from the model are realistic and represent the lake physics well in a long-term simulation. We also analyzed the snow depth on ice from 10 Finnish lakes and vertical temperature profiles from 5 Finnish lakes and the model results are realistic.
Microfluidic enrichment of plasma cells improves treatment of multiple myeloma
Authors: Zeng Yunjing , Gao Li , Luo Xiaoqing , Chen Yan , Kabeer Mustafa H. , Chen Xuelian , Stucky Andres , Loudon William G. , Li Shengwen C. , Zhang Xi , Zhong Jiang F. 
Published: April 2018

Cytogenetic alterations form the basis for risk stratification for multiple myeloma (MM) and guide the selection of therapy; however, current pathology assays performed on bone marrow samples can produce false‐negatives due to the unpredictable distribution and rarity of MM cells. Here, we report on a microfluidic device used to facilitate CD45 depletion to enhance the detection of cytogenetic alterations in plasma cells (PCs). Bone marrow samples from 48 patients with MM were each divided into two aliquots. One aliquot was subjected to classic flow cytometry and fluorescent in situ hybridization (FISH). The other first went through CD45+ cell depletion, further enriched by microfluidic size selection. The enriched samples were then analyzed using flow cytometry and FISH and compared to those analyzed using the classic method only. Unlike the traditional method, the microfluidic device removed the CD45+ leukocytes and specifically selected PCs from the remaining white blood cells. Therefore, the microfluidic method (MF‐CD45‐TACs) significantly increased the percentage of CD38+/CD138+ cells to 37.7 ± 20.4% (P < 0.001) from 10.3 ± 8.5% in bone marrow. After the MF‐CD45‐TAC enrichment, the detection rate of IgH rearrangement, del(13q14), del(17p), and 1q21 gains, rose to 56.3% (P < 0.001), 37.5% (P < 0.001), 22.9% (P < 0.001), and 41.7% (P = 0.001), respectively; all rates of detection were significantly increased compared to the classically analyzed samples. In this clinical trial, this microfluidic‐assisted assay provided a precise detection of cytogenetic alterations in PCs and improved clinical outcomes.
Novel Scale‐Like Structures of Graphite/TiC/Ti3C2 Hybrids for Electromagnetic Absorption
Authors: Li Mian , Han Meikang , Zhou Jie , Deng Qihuang , Zhou Xiaobing , Xue Jianmin , Du Shiyu , Yin Xiaowei , Huang Qing 
Published: April 2018

AbstractElectromagnetic (EM) absorbing and shielding materials have attracted great interests due to the increasing electromagnetic pollutions in the past years. Microstructure plays a crucial role in determining the performance of the above materials. Herein, a scale‐like structure based on Ti3C2 Mxenes is proposed to approach improved EM absorption properties. For the first time, graphite/TiC/Ti3AlC2 (G/TiC/Ti3AlC2) hybrids are fabricated in a molten salts bath and graphite/TiC/Ti3C2 (G/TiC/Ti3C2) hybrids are obtained after Al atoms are etched from G/TiC/Ti3AlC2. In G/TiC/Ti3C2, Ti3C2 sheets are perpendicular to the plane of G/TiC, which like a bionic structure of fish scale. The scale‐like G/TiC/Ti3C2 hybrids are dispersed in paraffin matrix to evaluate the EM properties. Owing to the structure‐induced EM absorption mechanism, G/TiC/Ti3C2 show much enhanced EM absorption ability than those materials without structure design, e.g., G/TiC/Ti3AlC2, pure Ti3C2, G/TiC, and the simple mixture of G/TiC with Ti3C2 (G/TiC+Ti3C2). The minimum reflection coefficient (RC) of G/TiC/Ti3C2 with the sample thickness of 2.1 mm reaches −63 dB and the effective absorption bandwidth (the frequency where RC is lower than −10 dB) is more than 3.5 GHz. The results indicate that the scale‐like structure can greatly improve the EM absorption ability.
Clinical significance of esophageal invasion length for the prediction of mediastinal lymph node metastasis in Siewert type II adenocarcinoma: A retrospective single‐institution study
Authors: Koyanagi Kazuo , Kato Fumihiko , Kanamori Jun , Daiko Hiroyuki , Ozawa Soji , Tachimori Yuji 
Published: April 2018

AbstractAimThis study investigated whether esophageal invasion length (EIL) of a tumor from the esophagogastric junction could be a possible indicator of mediastinal lymph node metastasis and survival in patients with Siewert type II adenocarcinoma.MethodsOne hundred and sixty‐eight patients with Siewert type II tumor who underwent surgery were enrolled. Metastatic stations and recurrent lymph node sites were classified into cervical, upper/middle/lower mediastinal, and abdominal zones. EIL was correlated with overall metastasis or recurrence in individual zones and with survival.ResultsSiewert type II patients with an EIL of more than 25 mm (>25 mm EIL group) had a higher incidence of overall metastasis or recurrence in the upper and middle mediastinal zones than those with an EIL of less than or equal to 25 mm (≤25 mm EIL group) (P = .001 and P < .001). Disease‐free and overall survival in the >25 mm EIL group were significantly lower than those of the ≤25 mm EIL group (P < .001). None of the Siewert type II patients with metastasis or recurrence in the upper and middle mediastinal zones survived for more than 5 years. Only an EIL of more than 25 mm was a significant preoperative predictor of overall metastasis or recurrence in the upper and middle mediastinal zones (odds ratio, 8.85; 95% CI, 2.31‐33.3; P = .001).ConclusionA multimodal‐therapeutic strategy should be investigated in Siewert type II patients once the tumor has invaded more than 25 mm to the esophageal wall.
Bio‐inspired Domino oxa‐Michael/Diels–Alder/oxa‐Michael Dimerization of para‐Quinols
Authors: Green Nicholas J. , Connolly Catherine A. , Rietdijk Koen P. W. , Nichol Gary S. , Duarte Fernanda , Lawrence Andrew L. 
Published: April 2018

AbstractA bio‐inspired, pyrrolidine‐mediated, dimerization of para‐quinols has been developed. It represents one of the most complex, yet general, dimerization reactions ever disclosed, selectively forming four new bonds, four new rings, and eight new contiguous stereogenic centres. The para‐quinol starting materials are easily handled, bench‐stable compounds, accessed in just one step from aromatic feedstocks. The reaction can be scaled up to give grams of polycyclic material, primed for further elaboration.
Selective Monomethylation of Amines with Methanol as the C1 Source
Authors: Choi Geunho , Hong Soon Hyeok 
Published: April 2018

AbstractThe N‐monomethyl functionality is a common motif in a variety of synthetic and natural compounds. However, facile access to such compounds remains a fundamental challenge in organic synthesis owing to selectivity issues caused by overmethylation. To address this issue, we have developed a method for the selective, catalytic monomethylation of various structurally and functionally diverse amines, including typically problematic primary aliphatic amines, using methanol as the methylating agent, which is a sustainable chemical feedstock. Kinetic control of the aliphatic amine monomethylation was achieved by using a readily available ruthenium catalyst at an adequate temperature under hydrogen pressure. Various substrates including bio‐related molecules and pharmaceuticals were selectively monomethylated, demonstrating the general utility of the developed method.
Electrospinning of plant oil‐based, non‐isocyanate polyurethanes for biomedical applications
Authors: Aduba Donald C. , Zhang Keren , Kanitkar Akanksha , Sirrine Justin M. , Verbridge Scott S. , Long Timothy E. 
Published: April 2018

ABSTRACTNon‐isocyanate polyurethanes (NIPU) have rapidly emerged as a sustainable, less toxic, and environmentally friendly alternative to traditional isocyanate‐based thermoplastic polyurethane (TPU) synthesis. TPU is widely used in the medical industry due to its excellent mechanical properties and elasticity. However, little work has been done to synthesize and electrospin NIPU into fibrous mats for biomedical applications. In this work, melt polymerization of a plant oil‐based cyclic carbonate monomer with polyether soft segments and various diamines yielded isocyanate‐free, segmented poly(amide hydroxyurethane)s (PAHUs). Electrospinning of segmented PAHUs afforded ductile, free‐standing fibrous mats with Young's modulus values between 7 and 8 MPa, suitable for tissue scaffold applications. PAHU fiber mats exhibited 3–4 times greater water uptake than the electrospun TPU control, demonstrating potential utility in drug delivery. Fibroblasts adhered to electrospun PAHU fibrous mats with viability values over 90% after 72‐h, validating its biocompatibility. The results highlight the high performance and potential of electrospun isocyanate‐free polyurethanes mats for biomedical application. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46464.
Iron phthalocyanine coatings on the surface of carbon fibers and their improved interfacial interactions with poly(arylene ether)nitrile
Authors: Xu Mingzhen , Chen Lin , Qin Meng , Han Zengmao , Pan Hai , Lei Yangxue , Liu Xiaobo 
Published: April 2018

ABSTRACTRiveted carbon fibers (CFs) were fabricated via in situ thermopolymerization. Iron phthalocyanine was like rivets distributed on the surface of the acidulated CFs. The rivets were characterized by scanning electron microscopy (SEM) and distributed uniformly on the surface of the CFs with a uniform microsphere size of 120 nm. Next, the pristine and riveted CFs were used to prepare fiber‐reinforced poly(arylene ether)nitrile (PEN)‐based composites with a hot‐press molding technique. The creep behaviors of PEN on the pristine and riveted CFs were investigated by dynamic rheological measurements. Among the samples, the viscosities changed with the frequency, and the stress relaxation and Cole–Cole plots are presented and discussed in detail. These results indicated better interlocking between the PEN chains and the rivets on the surface of the CFs. The dynamic mechanical properties of the composites were examined in three‐point bending mode with a dynamic mechanical analyzer. The results indicate that the reduction of the tan δ peak height may have been due to the improved interfacial adhesion between the CFs and PEN. Additionally, the interfacial morphologies of the CF‐reinforced PEN composites were monitored; this also confirmed the improved adhesion between the PEN chains and the riveted CFs in comparison with that of the pristine CFs. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46466.
Influences of the chain structure of PE‐b‐PEG on the properties of PE/PE‐b‐PEG blend membranes prepared by TIPS
Authors: Zhong Wentao , He Feng , Li Peiyuan , Fu Zhisheng , Zhang Peibin , Zhu Liang , Fan Zhiqiang , Zhu Liping 
Published: April 2018

ABSTRACTIn this article, a series of diblock copolymer polyethylene‐b‐ poly(ethylene glycol)s (PE‐b‐PEGs) with various molecular weight of polyethylene segment was blended with linear low‐density PE. The PE/PE‐b‐PEG blend porous membranes with high porosity were obtained by thermally induced phase separation (TIPS) process. The isothermal crystallization kinetics of PE/LP/PE‐b‐PEG blends indicated that the introduction of PE‐b‐PEG could inhibit the growth rate of polyethylene crystals which could increase the pore size and porosity of the membranes. The PE/PE‐b‐PEG blend membranes with PE1300‐b‐PEG2200 showed the largest pore size and porosity due to its crystallization behavior during TIPS. The surface of the membranes became smoother and the morphology of the membranes could be effectively tuned by introducing PE‐b‐PEG. Compared with the PE membrane, the PE/PE‐b‐PEG blend membranes exhibited higher hydrophilicity (the water contact angle decreased from 112° to 84°), water permeability (the permeation flux increased from 80 to 440 L/m2 h under 0.1 MPa), rejection performance (completely reject carbon particles in the filtration of carbon ink solution), and fouling resistance (the value of protein adsorption dropped from 0.25 to 0.05 mg/cm2). The hydrophilicity and fouling resistance of PE/PE‐b‐PEG blend membranes increased as the length of PE segment in PE‐b‐PEGs decreased. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46499.