bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Palaeographic and Codicological (Re)assessment of the Opisthograph 4Q433a/4Q255
Authors: Aksu Ayhan 
Published: June 2019

AbstractA consideration of both the palaeographic and material features of a scroll provides scholars the opportunity to investigate the scribal culture in which a particular manuscript emerged. This article examines the papyrus opisthograph from Qumran containing 4QpapHodayot-like Text B, 4Q433a, and 4QpapSerekh ha-Yaḥada, 4Q255, on either side. There has been scholarly disagreement about this opisthograph with regard to a number of questions: (1) which of the two compositions was inscribed on the recto, (2) how the two compositions should be dated, and (3) which of the two texts was written first. This article looks at both compositions by means of palaeography and codicology. From this combined approach I deduce that 4Q433a was written first, on the recto of this papyrus manuscript. 4Q255 was added later, on the verso. Both compositions can be dated to the early first century BCE. This reconstruction makes it plausible that 4Q255 was a personal copy.
A New Architecture of Justice: Dan Kiley’s Design for the Nuremberg Trials
Authors: Somos Mark , Gostwyck-Lewis Morgan 
Published: June 2019

Abstract
Courtroom 600 in the Nuremberg Palace of Justice is one of the most iconic sites in the history of international criminal law. Yet the extensive literature on Courtroom 600 neglects the original 1945 drawings by the architect Dan Kiley, now in the archives of the Harvard Design School. This article revises our understanding of Courtroom 600 in light of these drawings. Among other findings it argues that Kiley, rather than Jackson or the Office of Strategic Services, was the main source of design decisions; that the secondary literature overemphasises film at the expense of architecture; and that the design of both Courtroom 600 and the entire reconstruction of the Palace of Justice offer valuable insights into this key moment in the history of international law.
Unintended Consequences of the Primacy of Politics in UN Peace Operations
Authors: Gauslå Engell Troels , Lindskov Jacobsen Katja 
Published: June 2019

Abstract
The trend towards a more robust use of force in UN peacekeeping operations has received considerable attention from scholars pointing to the risk of unintended consequences. Since the report of the High-Level Independent Panel on Peace Operations, the primacy of politics is expected from all UN peace operations. The unintended consequences stemming from this primacy of politics has received considerably less attention, especially in the context of the UN’s political missions. Through an analysis of the UN’s engagement with the crisis in Burundi in 2015–2016, the article shows how the UN’s political role was implemented in a specific case. The case demonstrates that unintended consequences from the primacy of politics have overlaps with those related to robust peacekeeping, but also differ on important aspects.
World Literatures, Cosmopolitan Publics
Authors: Szurmuk Mónica , Degiovanni Fernando 
Published: June 2019

Abstract
In this article we use the rich sources provided by the press coverage of the 1936 Congress of the PEN Club in Buenos Aires to examine international interactions around literature in times of violence and censorship. We contend that the Congress allows for a reading of the different worlds of literature beyond the traditional categories of text, reader, writer and critic. Our study moves away from canonical authors and literature as an institution to focus on World Literature as a form of experience. We focus on the producers and consumers of literature as embodied multilingual presences and thereby provide a more nuanced understanding of World Literature. Bruce Robbins’s notion of “cosmopolitanisms from below” allows us to rethink the notion of World Literature within the framework of a “lived” cosmopolitanism deployed at a time of political danger.
Types of Thyatirinae (Lepidoptera: Drepanidae) in the collection of the Zoological Institute of the Russian Academy of Sciences
Authors: MIRONOV VLADIMIR G. , ZOLOTUHIN VADIM V. 
Published: June 2019

The article deals with 14 taxa of the Thyatirinae moths, the types of most of which are kept in the collection of the Zoological Institute of the Russian Academy of Sciences (St. Petersburg). It is shown that the designation of lectotypes/holotypes of Thyatira hedemanni Christoph, 1885, Asphalia nigrofascicula Graeser, 1888, and Cymatophora or var. terrosa Graeser, 1888, by Laszlo & al. (2007) on the basis of specimens preserved in the collections of Berlin and London Museums was based on non-syntypic specimens, and that their designation as lectotypes needs to be corrected. Correct lectotypes are designated here for the taxa listed above as well for Gonophora dieckmanni Graeser, 1888, and Thyatira moellendorfi Fixsen, 1887; a lectotype of Cymatophora octogesima var. caucasica Krulikowsky, 1901, is designated from the collection of Kiev University. The following type localities are thereby fixed: Lagodekhi [Georgia] for Thyatira hedemanni Christoph, 1885, Pung Tung [Central Korea] for Thyatira moellendorfi Fixsen, 1887 and for Thyatira violacea Fixsen, 1887, Nikolaevsk-na-Amure [Far East of Russia] for Cymatophora or var. terrosa Graeser, 1888.
Evolution of the Warm-Core Structure during the Eyewall Replacement Cycle in a Numerically Simulated Tropical Cyclone
Authors: Wang Hui , Wang Yuqing , Xu Jing , Duan Yihong 
Published: June 2019

Abstract
This study examines the evolution of the warm-core structure during the secondary eyewall formation (SEF) and the subsequent eyewall replacement cycle (ERC) in a numerically simulated tropical cyclone (TC) under idealized conditions. Results show that prior to the SEF, the TC exhibited a double warm-core structure centered in the middle and upper troposphere in the eye region, and as the storm intensified with a rapid outward expansion of tangential winds, the warm core strengthened and a secondary off-center warm ring developed between 8- and 16-km heights near the outer edge of the eye. During the SEF, both the upper-level warm core and the secondary off-center warm ring rapidly strengthened. As the secondary eyewall intensified and contracted and the primary eyewall weakened and dissipated, the off-center warm ring extended inward and merged with the inner warm core to form a warm core typical of a single-eyewall TC. Results from the azimuthal-mean potential temperature budget indicate that the warming in the eye is due to subsidence and the warming above 14-km height outside the eye is largely contributed by radial warm advection in the outflow. The development of the off-center warm ring is largely due to the subsidence warming near the inner edge of the primary eyewall and in the moat area and the warming by diabatic heating in the upper part of the inner eyewall below 14-km height. Further analysis indicates that the eddy advection also played some role in the warming above 12-km height in the upper troposphere.
Attributing Historical and Future Evolution of Radiative Feedbacks to Regional Warming Patterns using a Green’s Function Approach: The Preeminence of the Western Pacific
Authors: Dong Yue , Proistosescu Cristian , Armour Kyle C. , Battisti David S. 
Published: June 2019

AbstractGlobal radiative feedbacks have been found to vary in global climate model (GCM) simulations. Atmospheric GCMs (AGCMs) driven with historical patterns of sea surface temperatures (SSTs) and sea ice concentrations produce radiative feedbacks that trend toward more negative values, implying low climate sensitivity, over recent decades. Freely evolving coupled GCMs driven by increasing CO2 produce radiative feedbacks that trend toward more positive values, implying increasing climate sensitivity, in the future. While this time variation in feedbacks has been linked to evolving SST patterns, the role of particular regions has not been quantified. Here, a Green’s function is derived from a suite of simulations within an AGCM (NCAR’s CAM4), allowing an attribution of global feedback changes to surface warming in each region. The results highlight the radiative response to surface warming in ascent regions of the western tropical Pacific as the dominant control on global radiative feedback changes. Historical warming from the 1950s to 2000s preferentially occurred in the western Pacific, yielding a strong global outgoing radiative response at the top of the atmosphere (TOA) and thus a strongly negative global feedback. Long-term warming in coupled GCMs occurs preferentially in tropical descent regions and in high latitudes, where surface warming yields small global TOA radiation change but large global surface air temperature change, and thus a less-negative global feedback. These results illuminate the importance of determining mechanisms of warm pool warming for understanding how feedbacks have varied historically and will evolve in the future.
Anticancer Therapy at the End of Life: Lessons From a Community Cancer Institute
Authors: Sivendran Shanthi , Lynch Selah , McNaughton Caitlyn , Wong Riley , Svetec Sarah , Moore Jason H. , Holliday Rachel , Oyer Randall A. , Newport Kristina 
Published: June 2019

Introduction: Studies have shown aggressive cancer care at the end of life is associated with decreased quality of life, decreased median survival, and increased cost of care. This study describes the patients most likely to receive systemic anticancer therapy at the end of life in a community cancer institute. Materials and Methods: We performed a retrospective cohort study of 201 patients who received systemic anticancer therapy in our institution and died between July 2016 and April 2017. Data collected included primary malignancy, hospice enrollment, healthcare utilization, Oncology Care Model (OCM) enrollment, and clinical assessments at last office visit prior to a treatment decision before death. We defined our outcome variable as the receipt of anticancer treatment in the last 14 days of a patient’s life. We evaluated 20 clinical exposure variables with respect to the outcome classes. Risk ratios along with their associated confidence intervals and P values were calculated. Significance was determined using the Benjamini-Hochberg procedure to account for multiple testing. Results: Of the 201 patients who died of cancer, 36 (17%) received anticancer therapy within the last 14 days of life. Several risk factors were significantly positively associated with receiving anticancer therapy at the end of life including hospitalization within 30 days of end of life, number of hospitalizations per patient (≥2), death in hospital, enrollment in OCM, and a diagnosis of hematologic malignancy. Conclusion: Our findings demonstrate those enrolled in the OCM and those with hematologic malignancies have a higher risk of receiving anticancer therapy in the last 14 days of life. These observations highlight the need for better identifying the needs of high-risk patients and providing good quality care throughout the disease trajectory to better align end-of-life care with patients’ wishes.
A VaR-based Downside Risk Analysis of Indian Equity Mutual Funds in the Pre- and Post-global Financial Crisis Periods
Authors: Deb Soumya Guha 
Published: June 2019

This article analyses downside risk of Indian equity mutual funds from 1999 to 2014 using a value at risk (VaR)-based approach. We use weekly return data of a sample of 349 equity mutual funds during the said period to estimate their weekly VaRs on a rolling basis using some parametric and non-parametric models. Moving average (MA), exponentially weighted MA and GARCH (1, 1) are the parametric models and historical simulation (HS) is the non-parametric model. We also carry out backtesting of the models using three popular approaches—two under the unconditional coverage approach, namely Jorion’s ‘Failure Rate’ approach and Kupiec’s proportion of ‘failures’ (POF) test, and one under the conditional coverage approach, namely the Christoffersen’s Independence test—to test the robustness of the VaR models. Our results show that Indian equity mutual funds exhibit considerable downside risk during the chosen period, in terms of the magnitude of the projected VaRs. Moreover, significant proportions of the funds ‘fail’ the predicted VaRs, particularly during times of crisis for some of the models, raising questions about their robustness in an investment setting in India. On the whole, both from failure proportion as well as backtesting perspective, the GARCH (1,1) seems to be the most robust of the models. JEL codes: G32, G15, G23
Titanium cage reconstruction of acetabular defects in revision hip arthroplasty results in favourable outcomes: up to 17 years follow-up
Authors: Akel İbrahim , Cağlar Ömür , Tokgözoğlu A Mazhar , Atilla Bülent 
Published: June 2019

Introduction: Titanium cages are valuable implant solutions in management of severe acetabular defects during total hip revisions. We aimed to report clinical and radiological results of our cases in which we used titanium cages for reconstruction of acetabular defects. Methods: Patients underwent titanium cage reconstruction and bone grafting for their acetabular defects with minimum 2 year-follow-up are included to the study. Analysis of patient records, modified Hospital for Special Surgery hip score and radiological examinations on plain X-rays were evaluated. Acetabular defects are classified according to Paprosky’s classification. Kaplan Meier survival analysis is performed. Results: Fifty-six hips of 54 patients (2 bilateral) aged between 29-79 (mean 57 years ) are followed up for 7.06 years ±3.72 (2-17 years). Five patients required revision surgeries at a mean of 2.6±2.2 years. Kaplan Meier’s analysis revealed a survival rate of 91,5 % and mean revision free duration was 15,66±0,56 years. HSS scores of the patients before revision surgery yielded a mean score of 27,9 ± 4,9 (14-38). HSS scores at final follow up showed a significant improvement at a mean score of 45,9 ± 7 (28-56) differences were statistically significant, p<0,001) Discussion: Titanium cages are successful for restoring bone stock in severe acetabular defects. It is critical to pay attention on meticulous bone grafting of the presented defects and obtain good hip mechanics during cage insertion. Mechanical reasons are the leading cause of failure in long term but restoration of the bone stock and improvement in defect severity were regularly observed even in failed cages.
Social Presence Theory: Relevance for HRD/VHRD Research and Practice
Authors: Bickle Jason T. , Hirudayaraj Malar , Doyle Alaina 
Published: June 2019

The ProblemSocial presence theory (SPT) is the degree to which a person is perceived to be a “real person” in their computer-mediated communication or virtual environments. The level of social presence influences the quality of virtual interactions and outcomes. SPT has not been examined within human resource development (HRD) or virtual human resource development (VHRD); therefore, it is not known if increased social presence could improve virtual teams/organizations and online instruction.The SolutionDesigning online environments and practices to increase social presence could enhance VHRD within virtual teams, online instructional design, and educational settings. Application of Community of Inquiry (CoI), Social Presence Model, and SPT-inspired instructional design through Gagne’s nine events are discussed with recommendations to improve HRD/VHRD by fostering trust, communication, collaboration, personal relationships, and learning within virtual resources and teams.The StakeholdersThe literature and application of SPT would benefit HRD/VHRD researchers, HR practitioners, educators, and team leaders/managers.
Tumour incidence in Fabry disease: A cross-sectional study
Authors: Rossi Federica , Auricchio Sara , Binaggia Agnese , L’imperio Vincenzo , Pagni Fabio , Pieruzzi Federico 
Published: June 2019

Background: Recently, a possible correlation between altered glycosphingolipid metabolism, that occurs in Fabry disease, and cancer development has been suggested. We analysed both incidence and prevalence of benign and malignant tumours in a Fabry patient cohort and compared them with the Italian general population. The analysis of major risk factors was performed. Methods: A total of 53 Fabry patients, followed by Nephrology Unit of San Gerardo Hospital (Monza, Italy), were retrospectively enrolled. Primary outcome was cancer development during the follow-up period (2007–2017). Cancer prevalence and incidence rate were calculated and compared to those in the Italian general population, acquired from public report on cancer estimates produced by the Cancer Registers’ Italian Association. Fisher’s exact test and multivariate analysis were performed to identify significant risk factors. Results: Nine (17%) patients were diagnosed with malignant neoplasia (stage T1–T3, N0M0). Most of them were female (77.8%) and were 59 ± 9 years old. In the benign tumour group, different lesions, ranging from adenoma to dysplasia, were recorded. Italian cancer prevalence is currently 5.5%, while in our population it was 17%; the incidence rate ratio of the Fabry population compared with the general population was 2.66 (95% confidence interval from 1.33 to 5.32). The risk factor analysis has revealed that older age was a negative factor for cancer onset, while enzyme replacement therapy had a protective role effect against cancer in Fabry patients. Conclusion: Cancer could be an important associated pathology in Fabry patients. Their altered glycosphingolipid metabolism may have an oncogenic role. Further studies are needed to clarify the relationships between Fabry disease and cancer onset. Tumours in Fabry subjects could be diagnosed at an early stage allowing patients to have a concrete chance of treatment success.
B-cell acute lymphoblastic leukemia with high mutation burden presenting in a child with constitutional mismatch repair deficiency
Authors: Oshrine Benjamin , Grana Nanette , Moore Colin , Nguyen Johnny , Crenshaw Melissa , Edwards Melissa , Sudhaman Sumedha , Forster Victoria J. , Tabori Uri 
Published: June 2019

Key Points
Constitutional mismatch repair deficiency syndrome should be considered in children with acute leukemia and characteristic skin lesions. The high mutation burden of CMMRD-related cancers contributes to treatment resistance, necessitating individualized treatment strategies.
Cardiac angiosarcoma in a female adolescent: a case report
Authors: Oliveira Wlisses Ramon , Machado Carla Pérez , Moreira Marcelo Mendes Las Casas , de Siqueira Elisa Carvalho , de Souza Fabrício Tinôco Alvim , Prado Fabiano Franco Monteiro , Álvares Maria Carolina Barbosa , Antunes Paulo Ramos Botelho , Faleiro Cláudia Souza Freitas 
Published: June 2019

AbstractWe report a rare case of cardiac angiosarcoma in a female adolescent patient that is an unusual case of cardiac angiosarcoma. As the initial symptoms are nonspecific our case demonstrated difficulty to establish the correct diagnosis. Our patient has in addition to these, malaise, diarrhea and hemoptysis which was mistakenly diagnosed with pneumonia. Here, we discuss aspects of computed tomography with a definitive diagnosis confirmed by immunohistochemistry, through a transthoracic radioguided biopsy. The patient presented improvement after urgent chemotherapy, however, she died 4 months after initial symptoms. In view of these aspects, it is clear the need for early diagnosis and a definition of optimized treatment in order to extend the survival of these patients.
Neighbourhood greenness and depression among older adults
Authors: Perrino Tatiana , Lombard Joanna , Rundek Tatjana , Wang Kefeng , Dong Chuanhui , Gutierrez Carolina Marinovic , Toro Matthew , Byrne Margaret M. , Nardi Maria I. , Kardys Jack , Szapocznik José , Brown Scott C. 
Published: June 2019

BackgroundNeighbourhood greenness or vegetative presence has been associated with indicators of health and well-being, but its relationship to depression in older adults has been less studied. Understanding the role of environmental factors in depression may inform and complement traditional depression interventions, including both prevention and treatment.AimsThis study examines the relationship between neighbourhood greenness and depression diagnoses among older adults in Miami-Dade County, Florida, USA.MethodAnalyses examined 249 405 beneficiaries enrolled in Medicare, a USA federal health insurance programme for older adults. Participants were 65 years and older, living in the same Miami location across 2 years (2010–2011). Multilevel analyses assessed the relationship between neighbourhood greenness, assessed by average block-level normalised difference vegetative index via satellite imagery, and depression diagnosis using USA Medicare claims data. Covariates were individual age, gender, race/ethnicity, number of comorbid health conditions and neighbourhood median household income.ResultsOver 9% of beneficiaries had a depression diagnosis. Higher levels of greenness were associated with lower odds of depression, even after adjusting for demographics and health comorbidities. When compared with individuals residing in the lowest tertile of greenness, individuals from the middle tertile (medium greenness) had 8% lower odds of depression (odds ratio 0.92; 95% CI 0.88, 0.96; P = 0.0004) and those from the high tertile (high greenness) had 16% lower odds of depression (odds ratio 0.84; 95% CI 0.79, 0.88; P < 0.0001).ConclusionsHigher levels of greenness may reduce depression odds among older adults. Increasing greenery – even to moderate levels – may enhance individual-level approaches to promoting wellness.Declaration of interestNone.