bluuebunny/crossref_metadata_2025_split huggingface dataset:
Female Sexual Function at Three Months Post-delivery in Spontaneous Labor and Cesarean Section
Authors: Suntoro Suntoro , Kayika I Putu G 
Published: October 2018

Objective: To study the comparison of encouragement, stimuli, orgasm,
pain and satisfaction of female sexual function at 3 months
postpartum between spontaneous delivery and cesarean section in Dr.
Cipto Mangunkusumo Hospital in Jakarta.

Method: This was an observational research, sexual function was
measured at three months post-delivery with Female Sexual Function
Index (FSFI) questionnaire. The study design used was cross sectional
with consecutive sampling. Analysis for comparative nonpaired
categorical variables was done using Chi square or Fisher analysis.
Analysis for confounding variables was carried out using multivariate
logistic regression.

Result: From 150 respondents, 43.3% had sexual dysfunction, with
52% of the spontaneous labor group and 34% of the cesarean section
group. Bivariate analysis showed that occurrence of sexual dysfunction
at three months post-spontaneous labor was 1.5 times higher
(95% CI 1.02-3.19) compared with cesarean section. Sexual encouragement
shows a two-fold difference (95% CI 1.17-3.40) compared
to cesarean section. However, orgasm disturbance was 8 times higher
(95% CI 1.90-3.58) in the spontaneous labor group, with confounding
variable of perineal rupture. Disturbance of sexual stimuli, satisfaction,
and pain were not significantly different between spontaneous
labor and cesarean section. Multivariate analysis found that spontaneous
labor was statistically significant for sexual dysfunction at
three months post-delivery in patients with sexual encouragement
(RR=2.716, p=0.008) and orgasm accession dysfunction (RR=
6.952, p=0.031). However, the more than 30 years old of age variable
was statistically significant in sexual dysfunction variable with RR=
2.60 and p=0.021.

Conclusion: Spontaneous labor is statistically significant for sexual
dysfunction at three months post-delivery, especially for sexual encouragement
and orgasm accession. Meanwhile, the variables with the
age of 30 years old or older of age were influential on sexual dysfunction,
especially to the sexual stimuli variable.

Keywords: labor method, sexual dysfunction, three months postdelivery
Endometrial Histology in Abnormal Uterine Bleeding with Risk Factors
Authors: Hasan Rudy , Suparman Eddy , Lengkong Rudy A 
Published: October 2018

Objective: To determine the endometrial histology in abnormal
uterine bleeding (AUB) patients with risk factors.

Method: This study involved 30 patients with complaints of AUB,
aged over 35 years with associated risk factors of parity, obesity and
fasting blood glucose in the outpatient clinic at Prof. Dr. R. D. Kandou
General Hospital Manado, from July 2013 until October 2013.
Patients who agreed to be involved in this study, underwent dilatation
and curettage (D&C) to assess the endometrial histology that was
grouped as the hyperplasia and non-hyperplasia groups.

Result: From the results of the study, 7 patients were in the 35-40
years age group (23.3%) and in the 41-50 years age group were 23 patients
(76.7%). Based on parity, 11 patients (36.7%) were nulliparous
and 19 patients (63.3%) were multiparous. Based on the BMI, 16 patients
(53.5%) were obese and 14 patients (46.7%) were non-obese.
And based on the results of fasting blood sugar, similar results was
obtained in normal and abnormal fasting blood glucose with the results
of 15 patients in each groups (50%). And from all of patients
who underwent D&C, endometrial hyperplasia was shown in 21 patients
(70%) and non-hyperplasia endometrium in 9 patients (30%).
From the results of Fischer exact test, a significantly high association
was obtained between BMI and fasting blood glucose with the occurrence
of endometrial hyperplasia.

Conclusion: There is a significant relationship between BMI and high
fasting blood glucose with endometrial hyperplasia.
[Indones J Obstet Gynecol 2015; 3: 146-150]
Keywords: age, AUB, BMI, endometrial hyperplasia, fasting blood
sugar, parity
p53 Gene Codon 72 Polymorphisms among Cervical Carcinoma Patients
Authors: Basyar Rustham , Saleh Agustria Z , Sastradinata Irawan , Yuwono Yuwono 
Published: October 2018

Objective: To identify the association between p53 gene codon 72
polymorphism and cervical carcinoma.
Method: An analytic observational study with case-control design,
from November 2013 until March 2014 in the Department of Obstetrics
and Gynecology and Microbiology Laboratory Faculty of Medicine,
Sriwijaya University, Dr. Moh. Hoesin Hospital Palembang.
Result: In total there are 100 samples analyzed consisting of 50 subjects
and 50 control groups. Genotype distribution in subject group
are 54% Arg/Arg, 42% Pro/Arg and 4% Pro/Pro, and in control
group are 36% Arg/Arg, 46% Pro/Arg and 18% Pro/Pro. Arg/Arg
genotype is at risk of cervical carcinoma 6.7 times higher compared
with Pro/Pro genotype (p=0.013; OR 6.75; 95% CI 1.34-34.94). Arg
allele in the p53 gene codon 72 increase the risk of cervical carcinoma
2.6 times more than Pro allele.
Conclusion: Proline mutation to Arginine in gene p53 P72R is one of
the risk factor for cervical carcinoma.

Keywords: arginine, cervical carcinoma, gene p53 codon 72, polymorphism,
proline
PPARy Expression in Eutopic and Ectopic Endometrium of Reproductive Age Women with Endometriosis
Authors: Dilmy Adya F , Natadisastra Muharam , Sumapradja Kanadi 
Published: October 2018

Objective: To evaluate the expression of PPARy receptor and to
compare its expression in eutopic and ectopic endometrium in
women with endometriosis.
Method: This is a cross sectional study. Ten female subjects with endometriosis
that underwent laparoscopy or laparotomy who fulfilled
the inclusion criteria were recruited by consecutive sampling.
Two samples were taken, eutopic endometrium and ectopic endometrium
from endometriosis cyst wall during surgery of each
subject. PPARy expression was examined by two-step RT-qPCR. Our
data was statistically examined using the paired t-test and Pearson’s
correlation test.
Result: PPARy was found to be expressed in eutopic and ectopic endometrium
of women with endometriosis using the RT-qPCR method.
The expression of PPARy was not statistically different in
eutopic and ectopic endometrium (1.16 relative fold vs 1.25 relative
fold; p=0.26). By Pearson’s correlation there was a weak positive
correlation between PPARy expression of eutopic and ectopic endometrium
(r=0.16).
Conclusion: PPARy was detected by two-step RT-qPCR in eutopic
and ectopic endometrium of women with endometriosis. Semiquantification
of PPARy expression showed that there was no significant
difference between PPARy expression in eutopic and ectopic endometrium
of women with endometriosis. There was a weak positive
correlation between PPARy expression in eutopic and ectopic endometrium
of women with endometriosis.
[Indones J Obstet Gynecol 2015; 3-4: 200-205]
Keywords: endometriosis, PPARy, two-step RT-qPCR
Necessidade de leitos hospitalares para o SUS no estado do Paraná
Authors: Correa Barbosa Thamyres , Patricia Raksa Vivian , Letícia Unicki Ribeiro Annanda 
Published: October 2018

Este estudo tem como objetivo avaliar se a quantidade de leitos hospitalares SUS existentes no estado do Paraná está adequada à legislação vigente, assim como apresentar as alterações propostas pela Portaria GM/MS n°1631/15 em relação à anterior, Portaria GM/MS n.º 1.101/02, no que tange a programação de leitos hospitalares. O método utilizado foi pesquisa quanti-qualitativa com objetivos exploratórios e descritivos, que utilizou pesquisa biblio­gráfica e documental como procedimento de coleta de dados e o método comparativo para tratamento e análise dos dados. Destaca-se que a Portaria vigente considera a população de referência para cada leito-especialidade e pondera a redução da taxa de natalidade e ampliação proporcional da faixa etária de idosos para o cálculo da necessidade de leitos hospitalares. Conclui-se que o estado do Paraná atende ao quantitativo de leitos SUS estabelecido com base no cenário mínimo recomendado pela legislação vigente.
I-123-MIBG scintigraphy in patients with neuroblastoma
Authors: Amthauer Holger , Furth Christian , Hundsdoerfer Patrick , Wedel Florian , Schatka Imke , Rogasch Julian M.M. 
Published: October 2018

SummaryAim: According to German guidelines, I-123-MIBG scintigraphy in neuroblastoma (NB) is preferably performed as early (about 4 h p.i.) and late (24 h p.i.) planar imaging and single- photon emission computed tomography (SPECT) or SPECT/CT 24 h p.i. This study evaluated if the work-up could be reduced to a single timepoint.Methods: Retrospective analysis of 37 examinations in 26 patients (f:8; m:18; age, 0.5–23.5a) with NB (initial, 15; restaging, 22). All 74 (early + late) pairs of ventral/dorsal planar whole-body images were reviewed by 3 independent readers in random order blinded to clinical data (1, certainly physiological; 2, likely physiological; 3, likely malignant; 4, certainly malignant). CT/MRI or SPECT served as standard of reference if planar images were equivocal.Results: Two-hundred malignant lesions were rated (1–23 lesions per examination). The lesions’ mean score was higher at late vs. early imaging for all readers (3.6 vs. 3.4, 3.7 vs. 3.2, 3.5 vs. 3.2; each p < 0.01). Fifty-one lesions (25.5 %) were considerably underrated at early vs. late imaging (score difference ≥2) by any reader (29/153 skeletal lesions, 12/28 primary tumors [PT], 10/18 abdominal lymph nodes [LN]). Early image did not detect any lesion in 6 patients with PT only. In contrast, 9 lesions (4.5 %) were underrated by late vs. early imaging: 5 skeletal lesions (pelvis, 2; femoral shaft, 3), 1 PT, 3 LN, and 0/1 liver lesions. Tumor spread was underestimated thereby at late vs. early imaging in 1 patient (LN) but SPECT was correct.Conclusion: The early planar image provided no relevant information over the late image in any patient and may only be performed after weighting of risks (stress) and benefits – especially if SPECT or SPECT/CT is routinely performed. Vice versa, early planar image alone does not suffice.
Entwicklung eines kompetenzbasierten Lernzielkatalogs Nuklearmedizin für das Studium der Humanmedizin in Deutschland
Authors: Brenner Winfried , Buck Andreas , Franzius Christiane , Freudenberg Lutz , Gotthardt Martin , Lindner Oliver , Mottaghy Felix , Hellwig Dirk , Marienhagen Jörg 
Published: October 2018

Zusammenfassung
Ziele: Umsetzung der Vorgaben des Nationalen Kompetenzbasierten Lernzielkatalogs Medizin (NKLM, 2015) für ein Curriculum Nuklearmedizin im Auftrag des Ausschusses Fort- und Weiterbildung der Deutschen Gesellschaft für Nuklearmedizin (DGN). Methoden: 100 Lernziele (LZ) in 7 Domänen wurden in einem Delphi-Verfahren unter Einbeziehung aller habilitierten Mitglieder der DGN als Experten durch einen Fragebogen einer Priorisierung in 3 Kategorien (A, B und C) unterzogen. Kategorie A definierte für die jeden Arzt unerlässlichen LZ. Die Priorisierung} erfolgte durch Rangbildung nach dem Anteil der A- Klassifikationen. Eine LZ-Liste mit den Rangplätzen 1–5 in jeder Domäne wurde in der 2. Stufe des Delphi-Verfahrens den Experten der ersten Runde als Kern-Curriculum mit der Frage nach Akzeptanz bzw. Modifikationen vorgelegt. Ergebnisse: Die Ergebnisse der 1. Stufe des Delphi-Verfahrens) zeigte einen Rücklauf der Fragebögen von 29 % (55 von 184). Die 2. Runde erbrachte einen Rücklauf von 30,9 % (57 von 184) und eine uneingeschränkte Akzeptanz der vorgeschlagenen LZ in allen LZ-Domänen bei im Median 72 % der befragten Experten (61 % – 81 %). Die vorliegende Endfassung enthält 37 kompetenzbasierte LZ in den LZ-Domänen „Gesetzliche Grundlagen und Strahlenschutz”, „naturwissenschaftliche Grundlagen”, Indikationen und Kontraindikationen zu „PET/CT”, „Szintigraphie und SPECT”, „Patientenvorbereitung”, „Befundanalyse und -interpretation” sowie „Therapie”. Ausblick: Der kompetenzbasierte LZ-Katalog Nuklearmedizin beschreibt die Kenntnisse und Kompetenzen, über die jeder Arzt am Ende seines Studiums verfügen sollte. Der LZ-Katalog ist ein lebendes Dokument, das fortlaufend an den Fortschritt der medizinischen und technologischen Entwicklung angepasst werden muss.
Application of Accelerated Time Models to Compare Performance of Two Comorbidity-adjusting Methods with APACHE II in Predicting Short-term Mortality Among the Critically Ill
Authors: Bish Melanie , Fletcher Jason , Knott Cameron , Stephenson John , Mnatzaganian George 
Published: October 2018

Summary
Objective: This study aimed to determine how the abilities of the Charlson Index and Elixhauser comorbidities compared with the chronic health components of the Acute Physiology and Chronic Health Evaluation (APACHE II) to predict in-hospital 30 day mortality among adult critically ill patients treated inside and outside of Intensive Care Unit (ICU).
Methods: A total of 701 critically ill patients, identified in a prevalence study design on four randomly selected days in five acute care hospitals, were followed up from the date of becoming critically ill for 30 days or until death, whichever occurred first. Multiple data sources including administrative, clinical, pathology, microbiology and laboratory patient records captured the presence of acute and chronic illnesses. The exponential, Gompertz, Weibull, and log-logistic distributions were assessed as candidate parametric distributions available for the modelling of survival data. Of these, the log-logistic distribution provided the best fit and was used to construct a series of parametric survival models.
Results: Of the 701 patients identified in the initial prevalence study, 637 (90.9%) had complete data for all fields used to calculate APACHE II score. Controlling for age, sex and Acute Physiology Score (APS), the chronic health components of the APACHE II score, as a group, were better predictors of survival than Elixhauser comorbidities and Charlson Index. Of the APACHE II chronic health components, only the relatively uncommon conditions of liver failure (3.4%) and immunodeficiency (9.6%) were statistically associated with inferior patient survival with acceleration factors of 0.35 (95% CI 0.17, 0.72) for liver failure, and 0.42 (95% CI 0.26, 0.72) for immunodeficiency. Sensitivity analyses on an imputed dataset that also included the 64 individuals with imputed APACHE II score showed identical results.
Conclusion: Our study suggests that, in acute critical illness, most co-existing comorbidities are not major determinants of shortterm survival, indicating that observed variations in ICU patient 30-day mortality may not be confounded by lack of adjustment to pre-existing comorbidities.
A Comparison of Angular Values of the Pelvic Limb with Normal and Medial Patellar Luxation Stifles in Chihuahua Dogs Using Radiography and Computed Tomography
Authors: Phetkaew Thitaporn , Kalpravidh Marissak , Penchome Rampaipat , Wangdee Chalika 
Published: October 2018

Objective This article aimed to determine and compare the angular values of the pelvic limb in normal and medial patellar luxation (MPL) stifles in Chihuahuas using radiography and computed tomographic (CT) scan, to identify the relationship between pelvic limb angles and severity of MPL. In addition, radiographic and CT images were compared to determine the more suitable method of limb deformity assessment.
Methods Sixty hindlimbs of Chihuahuas were divided into normal and grade 1, 2, 3 and 4 MPL groups. The pelvic limb angles in frontal and sagittal planes were evaluated on radiography and CT scan. Femoral and tibial torsion angles (FTA and TTA) were evaluated only by CT scan. All angles were compared among normal and MPL stifles and between radiography and CT scan.
Results Based on the CT scan, the mechanical lateral distal femoral angle (mLDFA), anatomical caudal proximal femoral angle (aCdPFA), and TTA were related to the severity of MPL. The mLDFA and TTA were significantly increased (p < 0.05) in grade 4 MPL, while the aCdPFA was significantly decreased in grade 2, 3 and 4 MPL groups. There were significant differences of many angles between radiography and CT scan.
Clinical Significance The angles related to MPL in Chihuahuas are aLDFA, mLDFA, aCdPFA and TTA. Radiography had some limitations for evaluating pelvic limb angles. The caudocranial radiograph is recommended for the assessment of the distal femoral angles, while the craniocaudal radiograph is for the tibial angles.
The Environments of the Most Energetic Gamma-Ray Bursts
Authors: Gompertz B. P. , Fruchter A. S. , Pe’er A. 
Published: October 2018

Abstract
We analyze the properties of a sample of long gamma-ray bursts (LGRBs) detected by the Fermi satellite that have a spectroscopic redshift and good follow-up coverage at both X-ray and optical/near infrared wavelengths. The evolution of LGRB afterglows depends on the density profile of the external medium, enabling us to separate wind or interstellar medium (ISM)-like environments based on the observations. We do this by identifying the environment that provides the best agreement between estimates of p, the index of the underlying power-law distribution of electron energies, as determined by the behavior of the afterglow in different spectral/temporal regimes. At 11 rest-frame hours after trigger, we find a roughly even split between ISM-like and wind-like environments. We further find a 2σ separation in the prompt emission energy distributions of wind-like and ISM-like bursts. We investigate the underlying physical parameters of the shock, and calculate the (degenerate) product of density and magnetic field energy (ϵ

B
). We show that ϵ

B
must be

to avoid implied densities comparable to the intergalactic medium. Finally, we find that the most precisely constrained observations disagree on p by more than would be expected based on observational errors alone. This suggests additional sources of error that are not incorporated in the standard afterglow theory. For the first time, we provide a measurement of this intrinsic error that can be represented as an error in the estimate of p of magnitude 0.25 ± 0.04. When this error is included in the fits, the number of LGRBs with an identified environment drops substantially, but the equal division between the two types remains.
The First Glitch in a Central Compact Object Pulsar: 1E 1207.4–5209
Authors: Gotthelf E. V. , Halpern J. P. 
Published: October 2018

Abstract
Since its discovery as a pulsar in 2000, the central compact object (CCO) 1E 1207.4−5209 in the supernova remnant PKS 1209−51/52 had been a stable 0.424 s rotator with an extremely small spin-down rate and weak (

G) surface dipole magnetic field. In 2016 we observed a glitch from 1E 1207.4−5209 of at least

, which is typical in size for the general pulsar population. However, glitch activity is closely correlated with spin-down rate

, and pulsars with

as small as that of 1E 1207.4−5209 are never seen to glitch. Unlike in glitches of ordinary pulsars, there may have been a large increase in

as well. The thermal X-ray spectrum of 1E 1207.4−5209, with its unique cyclotron absorption lines that measure the surface magnetic field strength, did not show any measurable change after the glitch, which rules out a major disruption in the dipole field as a cause or result of the glitch. A leading theory of the origin and evolution of CCOs, involving the prompt burial of the magnetic field by the fallback of supernova ejecta, might hold the explanation for the glitch.
Extremely Dense Cores Associated with Chandra Sources in Ophiuchus A: Forming Brown Dwarfs Unveiled?
Authors: Kawabe Ryohei , Hara Chihomi , Nakamura Fumitaka , Saigo Kazuya , Kamazaki Takeshi , Shimajiri Yoshito , Tomida Kengo , Takakuwa Shigehisa , Tsuboi Yohko , Machida Masahiro N. , Francesco James Di , Friesen Rachel , Hirano Naomi , Oasa Yumiko , Tamura Motohide , Tamura Yoichi , Tsukagoshi Takashi , Wilner David 
Published: October 2018

Abstract
On the basis of various data such as ALMA, JVLA, Chandra, Herschel, and Spitzer, we confirmed that two protostellar candidates in Oph A are bona fide protostars or proto-brown dwarfs (proto-BDs) in extremely early evolutionary stages. Both objects are barely visible across infrared (IR; i.e., near-IR to far-IR) bands. The physical nature of the cores is very similar to that expected in first hydrostatic cores (FHSCs), objects theoretically predicted in the evolutionary phase prior to stellar core formation with gas densities of ∼1011–12 cm−3. This suggests that the evolutionary stage is close to the FHSC formation phase. The two objects are associated with faint X-ray sources, suggesting that they are in very early phase of stellar core formation with magnetic activity. In addition, we found the CO outflow components around both sources, which may originate from the young outflows driven by these sources. The masses of these objects are calculated to be ∼0.01–0.03 M
⊙ from the dust continuum emission. These physical properties are consistent with that expected from the numerical model of forming brown dwarfs. These facts (the X-ray detection, CO outflow association, and FHSC-like spectral energy distributions) strongly indicate that the two objects are proto-BDs or will be in the very early phase of protostars, which will evolve to more massive protostars if they gain enough mass from their surroundings. The ages of these two objects are likely to be within ∼103 years after the protostellar core (or second core) formation, taking into account the outflow dynamical times (≲500 years).
NLTE Line Formation for Mg i and Mg ii in the Atmospheres of B–A–F–G–K Stars
Authors: Alexeeva Sofya , Ryabchikova Tatiana , Mashonkina Lyudmila , Hu Shaoming 
Published: October 2018

Abstract
Non-local thermodynamical equilibrium (NLTE) line formation for Mg i and Mg ii lines is considered in classical 1D LTE model atmospheres of the Sun and 17 stars with reliable atmospheric parameters and in a broad range of spectral types: 3900 K ≤

≤ 17,500 K, 1.1 ≤ log g ≤ 4.7, and −2.6 ≤ [Fe/H] ≤ +0.4. We find that, for each star, NLTE leads to smaller line-to-line scatter. For 10 stars, NLTE leads to consistent abundances of Mg i and Mg ii, while the difference in LTE abundance varies between −0.21 and +0.23 dex. We obtain an abundance discrepancy between Mg i and Mg ii in two very metal-poor stars, HD 140283 and HD 84937. The origin of these abundance differences remains unclear. Our standard NLTE modeling predicts Mg i emission lines at 7.736, 11.789, 12.224, and 12.321 μm in the atmospheres with

≤ 7000 K. We reproduce well the Mg i 12.2 and 12.3 μm emission lines in Procyon. However, for the Sun and three K-giants, the predicted Mg i emission lines are too weak compared with the observations. For stars with 7000 K ≤

≤ 17,500 K, we recommend the Mg ii 3848, 3850, 4384, 4390, 4427, and 4433 Å lines for Mg abundance determinations even at the LTE assumption due to their small NLTE effects. The Mg i 4167, 4571, 4702, 5528, 5167, 5172, and 5183 Å lines can be safely used in the LTE analysis of stars with 7000 K <

≤ 8000 K. For the hotter stars, with

from 8000 K to 9500 K, the NLTE effects are minor only for Mg i 4167, 4702, and 4528 Å.
150 years of new beetles (Coleoptera) described in The Canadian Entomologist and associated publications (1868–2017)
Authors: Bouchard P. , Brunke A.J. , Davies A.E. , Douglas H. , Smith A.B.T. , Manoogian J. 
Published: October 2018

AbstractThe Canadian Entomologist and its associated publications (Supplements of The Canadian Entomologist and Memoirs of the Entomological Society of Canada) have served as important outlets for taxonomic contributions on arthropods since 1868. A survey of beetle (Coleoptera) publications therein has revealed that 2276 species-group, 136 genus-group, and seven family-group taxa were first described in 492 scientific articles. New beetles were described in 67 families by 165 authors. We document trends of beetle descriptions over time, by taxonomic group and by the origin of the new taxa. We also provide biographical notices of the entomologists who described the new taxa. We believe that The Canadian Entomologist will continue to be coveted as a suitable outlet for taxonomic works in the future.