bluuebunny/crossref_metadata_2025_split huggingface dataset:
GnuR Represses the Expression of Glucose and Gluconate Catabolism in Pseudomonas putida KT2440
Authors: Chen Wenbo , Ma Rao , Feng Yong , Xiao Yunzhu , Sekowska Agnieszka , Danchin Antoine , You Conghui 
Published: November 2024

ABSTRACTIn Pseudomonas putida KT2440, a prime chassis for biotechnology, the clustered distribution of glucose catabolism genes and four related transcription factors (TFs) may facilitate the tight regulation of glucose catabolism. However, the genes under the direct control of these TFs remain unidentified, leaving their regulatory roles elusive. Furthermore, the carbon source gluconate was metabolised similarly to glucose in KT2440, but the responses of these catabolic and TF genes to gluconate were unclear. Here, these mysteries were unravelled through multi‐omics analysis integrated with physiological studies. First, we found that the expression of these catabolic and TF genes were significantly induced by both glucose and gluconate in KT2440. The independent responses of these genes to glucose and gluconate were differentiated in the gcd deletion mutant. We then defined the regulon of GnuR, one of the four related TFs, and discovered that GnuR directly repressed the expression of catabolic genes involved in the Entner–Doudoroff and the peripheral glucose and gluconate metabolism pathways. These results were further confirmed by physiological studies. Finally, a regulatory mode of an incoherent feedforward loop involving GnuR is proposed.
Rare Causes and Differential Diagnosis in Patients With Silver‐Russell Syndrome
Authors: Braga Barbara Leitao , da Cunha Scalco Renata , Homma Thais Kataoka , Freire Bruna Lucheze , Cellin Laurana De Polli , Canton Ana Pinheiro Machado , Lerario Antônio Marcondes , de Assis Funari Mariana Ferreira , de Souza Vinicius , Bertola Debora Romeo , Malaquias Alexsandra Christianne , Mendonca Berenice Bilharinho , de Lima Jorge Alexander Augusto 
Published: November 2024

ABSTRACTSilver‐Russell syndrome (SRS) is an imprinting disorder mainly characterized by pre‐ and postnatal growth restriction. Most SRS cases are due to 11p15.5 loss of methylation (11p15.5 LOM) or maternal uniparental disomy of chromosome 7 [UPD(7)mat], but several patients remain molecularly undiagnosed. This study describes the molecular investigation of children with a clinical diagnosis or suspicion of SRS at a tertiary center specialized in growth disorders. Thirty‐nine patients were evaluated with multiplex ligation‐dependent probe amplification, chromosomal microarray and/or massively parallel sequencing. The most common result was 11p15.5 LOM (n = 17; 43.5%), followed by UPD(7)mat (n = 2; 5.1%). Additionally, we found maternal duplications of the imprinting centers in 11p15.5 (n = 2; 5.1%), and genetic defects in SRS‐causing genes (IGF2 and HMGA2) (n = 3; 7.7%; two mutations and one deletion). Alternative molecular diagnoses included UPD(14)mat (n = 1; 2,6%), UPD(20)mat (n = 1;2,6%), copy number variants (n = 2; 5.1%), and mutations in genes associated with other growth disorders (n = 4; 10.3%), leading to diagnoses of Temple syndrome, Mulchandani‐Bhoj‐Conlin syndrome, IGF‐1 resistance (IGF1R), Bloom syndrome (BLM), Gabriele‐De Vries syndrome (YY1), Intellectual developmental disorder autosomal dominant 50 with behavioral abnormalities (NAA15), and Intellectual developmental disorder 64 (ZNF292). These findings underscore the importance of establishing the molecular diagnosis of SRS and its differential diagnoses to guide appropriate management and genetic counseling.
Machine learning‐aided prediction of windstorm‐induced vibration responses of long‐span suspension bridges
Authors: Entezami Alireza , Sarmadi Hassan 
Published: November 2024

AbstractLong‐span suspension bridges are significantly susceptible to windstorm‐induced vibrations, leading to critical challenges of field measurements along with multicollinearity and nonlinearity between wind features and bridge dynamic responses. To address these issues, this article proposes an innovative machine learning‐assisted predictive method by integrating a predictor selector developed from regularized neighborhood components analysis and kernel regression modeling through a regularized support vector machine adjusted by Bayesian hyperparameter optimization. The crux of the proposed method lies in advanced machine learning algorithms including metric learning, kernel learning, and hybrid learning integrated in a regularized framework. Utilizing the Hardanger Bridge subjected to different windstorms, the performance of the proposed method is validated and then compared with state‐of‐the‐art regression techniques. Results highlight the effectiveness and practicality of the proposed method with the minimum and maximum R‐squared rates of 89% and 98%, respectively. It also surpasses the state‐of‐the‐art regression techniques in predicting bridge dynamics under different windstorms.
Social virtual reality for L2 Spanish development: Learning how to interact with others in a high‐immersion virtual space
Authors: Taguchi Naoko , Hanks Elizabeth 
Published: November 2024

AbstractResearch indicates that high‐immersion virtual reality (VR) has several unique affordances for language learning that contribute to learning outcomes, such as boosting learners’ confidence, engagement, and motivation. However, little is known about the extent to which VR promotes language skills, in particular learners’ verbal interaction using a second language (L2). The present study uses an intervention design to examine the impact of high‐immersion VR on L2 Spanish learners’ interactional development and perceptions of VR experience. Twenty‐six beginning‐level Spanish learners engaged in four social VR sessions over a 2‐week period. Learners’ perceptions of social VR were assessed through surveys and focus group interviews, and their changes in interaction‐involved language performance were evaluated. The results reinforce previous research in showing that learners felt a heightened sense of presence in VR and that interacting in Spanish in the immersive virtual space was more enjoyable and less nerve‐wracking than face‐to‐face conversation, albeit equally beneficial to learning. Quantitative analyses of learners’ interaction revealed significant improvement in terms of their engagement, clarity, and content appropriateness. However, participants reported that technical issues could at times limit the pedagogical usefulness of VR. These findings reinforce the use of social VR in L2 instruction and provide novel insights about performance gains and Spanish L2 pedagogy in a virtual space.
Rapidly Progressive Idiopathic Pyoderma Gangrenosum in a Pediatric Patient Successfully Treated With Infliximab
Authors: Perry Nikhita J. , Wang Stephanie , Smith Robert , Duffy Robert , Queenan Maria , Perman Marissa J. , Lerman Melissa A. , Larijani Mary 
Published: November 2024

ABSTRACTPyoderma gangrenosum (PG) is a rare skin disorder with poorly understood pathophysiology. PG infrequently occurs in children, and approximately 4% of patients with PG are infants and children. First line therapy is topical and systemic corticosteroids, which typically yields rapid response. We report a case of rapidly progressive pediatric PG of unknown inciting cause that ultimately required multi‐modal therapy with systemic and topical corticosteroids, high‐dose infliximab, and colchicine.
Chemical activation of ABA signaling in grapevine through the iSB09 and AMF4 ABA receptor agonists enhances water use efficiency
Authors: Bono Mar , Ferrer‐Gallego Raul , Pou Alicia , Rivera‐Moreno Maria , Benavente Juan L. , Mayordomo Cristian , Deis Leonor , Carbonell‐Bejerano Pablo , Pizzio Gaston A. , Navarro‐Payá David , Matus José Tomás , Martinez‐Zapater Jose Miguel , Albert Armando , Intrigliolo Diego S. , Rodriguez Pedro L. 
Published: November 2024

AbstractGrapevine (Vitis vinifera L.) is the world's third most valuable horticultural crop, and the current environmental scenario is massively shifting the grape cultivation landscape. The increase in heatwaves and drought episodes alter fruit ripening, compromise grape yield and vine survival, intensifying the pressure on using limited water resources. ABA is a key phytohormone that reduces canopy transpiration and helps plants to cope with water deficit. However, the exogenous application of ABA is impractical because it suffers fast catabolism, and UV‐induced isomerization abolishes its bioactivity. Consequently, there is an emerging field for developing molecules that act as ABA receptor agonists and modulate ABA signaling but have a longer half‐life. We have explored the foliar application of the iSB09 and AMF4 agonists in the two grapevine cultivars cv. ‘Bobal’ and ‘Tempranillo’ to induce an ABA‐like response to facilitate plant adaptation to drought. The results indicate that iSB09 and AMF4 act through the VviPYL1‐like, VviPYL4‐like, and VviPYL8‐like ABA receptors to trigger stomatal closure, reduce plant transpiration, and increase water use efficiency. Structural and bioinformatic analysis of VviPYL1 in complex with ABA or these agonists revealed key structural determinants for efficient ligand binding, providing a mechanistic framework to understand receptor activation by the ligands. Physiological analyses further demonstrated that iSB09 has a more sustained effect on reducing transpiration than ABA, and agonist spraying of grapevine leaves protected PSII during drought stress. These findings offer innovative approaches to strengthen the vine's response to water stress and reduce plant consumptive water use under limited soil water conditions.
Higgs bundles in the Hitchin section over non‐compact hyperbolic surfaces
Authors: Li Qiongling , Mochizuki Takuro 
Published: November 2024

AbstractLet be an arbitrary non‐compact hyperbolic Riemann surface, that is, not the complex plane or punctured plane. Let be , or . We show that, on a Higgs bundle in the ‐Hitchin section over , there always exists a harmonic metric satisfying certain nice properties. Moreover, when the Higgs field has bounded spectral curve with respect to the complete hyperbolic metric on , such a harmonic metric is unique. As a result, we obtain a new proof of the existence and uniqueness of a harmonic metric for Higgs bundles in the ‐Hitchin section over a compact hyperbolic Riemann surface. Moreover, we show an existence result of harmonic metrics for a more general family of Higgs bundles that admit a full holomorphic filtration.
Thermal Characteristics and Dryer Performance Analysis of Double Pass Solar Collector Powered by Copper and Iron Oxide
Authors: Venkatesh R. , Venkatasubramanian R. , Singh Pradeep Kumar , Mayiladuthurai Vaidyanathan Ishwarya , Deshwal Deepti , Bhimeshwar Reddy S. D. V. V. S. , Soudagar Manzoore Elahi M. , Al Obaid Sami , Alharbi Sulaiman Ali 
Published: November 2024

Abstract
Solar renewable energy is prospective for various engineering applications including heat exchanger and air dryer applications. The drying of agricultural products is influenced by the weather, which can limit their dryness on cloudy days and reduce drying efficiency, often necessitating additional measures to complete the drying process. This research aims to enrich the functional characteristics of a double-pass solar collector configured with a dryer unit for drying agriculture products, namely, potato chips, banana chips, and red chilies. The solar collector features a hybrid black paint coating prepared by mixing copper oxide (CuO) and iron oxide (Fe3O4) via a spray pyrolysis route with 0.3 µm thickness. The effect of hybrid coating on air temperature, energy input, thermal efficiency, drying rate, moisture ratio, and exergy efficiency of the solar-coupled dryer was estimated and compared with non-coating conditions. The result of hybrid nano-enhanced coating shows superior thermal performance and dryer performance than other coating conditions. The peak air temperature, energy input, and average efficiency are about 66.5 °C, 359.7 W, and 69.7%, respectively. Furthermore, the red chilies show a better average drying rate, moisture ratio, and exergy efficiency of about 0.81 kg/h, 0.39, and 8.4%, respectively.
Numerical Investigations on Minimization of Convective Heat Losses From Hemispherical Cavity Receiver Using Air Curtain
Authors: Sandeep Raj R. , Dinesh N. , Vikram T. Srihari 
Published: November 2024

Abstract
In the present work, numerical investigations are carried out to study the effect of placing an air curtain at the aperture of the hemispherical cavity receiver of solar parabolic dish collector system to reduce convective heat losses. The effect of parameters like jet angle, jet velocity, cavity inclination, and surface temperature on convective heat loss is considered. The effect of jet angle and velocity plays an important role in controlling the heat losses from the receiver. At jet angle of −20 deg, air impinges inside the receiver surface thus diluting hot air inside the receiver. However, for jet angle of 0 deg and 20 deg, jet controls air escaping out of the receiver. There lies optimum jet velocity which can sustain hot air from leaving receiver. This study shows that using an air curtain for the hemispherical cavity receiver minimizes the convective heat losses up to 45% at optimum jet conditions. The convective heat loss is minimum (192 W) for the jet velocity of 2.5 m/s and jet angle of 20 deg which implies that the best containment effect from the air curtain can be obtained at this condition. Further, an artificial neural network model is formulated to predict the heat losses from the receiver for a range of functional parameters based on numerical simulations.
Tailoring the Tribomechanical and Corrosion Behavior of Reverse Pulse Deposited Ni–Co–P Coating Through Cobalt Content Modulation
Authors: Chakraborti Anurag , Das Suman Kalyan , Sahoo Prasanta 
Published: November 2024

Abstract
This study explores the influence of cobalt content on the tribomechanical and corrosion properties of Ni–Co–P coatings deposited through reverse pulse electroplating. The ratio of Co salt concentration to the total Ni and Co salt concentration was varied in the electrolyte to achieve different Co levels within relatively low cobalt (≤36 wt%) regime. X-ray diffraction revealed crystallite sizes of 1–3 nm in the deposited layers suggesting a mixture of amorphous and nanocrystalline structure. Critical loads in scratch adhesion tests are found to be in between 10.5 N and 15.1 N implying adequate adhesive bonding between the deposits and the substrates. Microhardness and pin-on-disc tribo test results demonstrate a positive correlation between Co content and both hardness and wear resistance of the coatings. However, incorporating small amounts of Co (≤6.2 wt%) exhibited minimal impact on these properties. Interestingly, corrosion resistance in saline medium peaked at the second-highest Co level (26.2 wt% of Co), followed by a decrease with further increase of Co. These findings indicate an optimal Co concentration for achieving a balance between wear resistance and corrosion protection in Ni–Co–P coatings.
An Extended Operational Modal Analysis Method Enabling the Separation of Whirling Direction Information in Rotating Machinery (Full Operational Modal Analysis Method)
Authors: Goto Daiki , Inoue Tsuyoshi , Kimura Shogo , Heya Akira , Nakamura Shinsaku , Watanabe Yusuke 
Published: November 2024

Abstract
Operational modal analysis (OMA) has recently been applied to the condition monitoring of rotating machinery. Conventional OMA is based on a one-dimensional signal. The natural modes of a rotating machinery can be classified into two types: a forward whirling mode and a backward whirling mode. Although the magnitudes of the natural frequencies of these two modes are separated by the gyroscopic effect, they can become close to each other and difficult to distinguish. This characteristic may make it difficult to apply conventional OMA based on a one-dimensional signal to rotating machinery. To monitor and diagnose the rotating machinery in the operating condition with high precision, it is necessary to develop the OMA method that can separate this information of the forward and backward whirling modes and can accurately estimate the vibration characteristics of each mode. However, only one previous report has addressed the application of OMA to rotating machinery with the capability of separating whirling direction information, and this approach requires an excitation signal. In this study, a novel OMA method, referred to as full OMA, has been developed, which is capable of separating forward and backward whirling direction information without the need for an excitation signal. To achieve this, signal data in both the x and y directions are acquired, and their autocorrelation and cross-correlation functions are calculated and combined as complex numbers. Spectral analysis of these functions yields a pseudo–full frequency response function (FRF), from which modal parameters for each whirling direction can be estimated. The validity and usefulness of the proposed full OMA method have been confirmed through both theoretical analysis and experimental validation. This full OMA method enables the accurate estimation of vibration characteristics for each whirling direction, even when the forward and backward natural frequencies are in close proximity. Consequently, the proposed full OMA method is highly effective for monitoring and diagnosing rotating machinery.
North Korea in the Twilight of Communism: Ideological Transformation and International Relations during the Cold War's Final Decade
Authors: Stock Thomas 
Published: November 2024

Abstract
The 1980s were a time of considerable ideological transformations in North Korea and the Soviet Union. North Korean leaders revived orthodox Marxism-Leninism, whereas the opposite was true in the Soviet Union, as Mikhail Gorbachev ushered in a fundamental reassessment of Marxism-Leninism that led to the downfall of ideological orthodoxy. Previous scholarship has barely explored this revival and the impact of Soviet ideological changes on North Korea. Drawing on newly released archival evidence and North Korean party publications, this article explores these interrelated and often contradictory phenomena. North Korea's revival of Marxism-Leninism, far from being superficial, was profound and strategically designed to link North Korean foreign policy much more closely with state ideology. The reoriented North Korean policy actively reached out to the Communist world to attain economic and diplomatic superiority vis-à-vis South Korea. Soviet ideological changes under Gorbachev threatened to undermine the DPRK's foreign policy goals and new ideological commitments, thus resulting in sharp ideological disagreements and ultimately the end of North Korea's Marxist-Leninist renaissance.
Sex-typed or Androgynous: Gender Representations in One Sentence Is Ten Thousand Sentences and The Blind Assassin
Authors: Shirazi Mozhgan , Hadaegh Bahee 
Published: November 2024

Abstract
Although the gender landscape has been experiencing a significant amount of change and flexibility in many parts of the world over the past few decades, societal messages regarding gender roles and expectations can still remain conventional. It is likely that such a perplexing paradox becomes reinforced while portraying male or female characters in fiction. Inspired by Sandra Bem’s gender schema theory introduced in 1981, this research aims to examine gender representations in the protagonists of two novels, namely The Blind Assassin and One Sentence Is Ten Thousand Sentences. Iris Chase and Yung Baishun (Wu Moxi) are analyzed according to a modified version of The Bem Sex-Role Inventory (BRSI) to see whether they’re sex-typed (masculine or feminine) or androgynous. The results calculated in an “androgyny ratio” (AR) indicate that while Atwood’s character is marked as feminine, Yung Baishun is characterized as androgynous according to BRSI.
Providence Community: Building Vulnerable Community to Overcome the Cycle of Violence
Authors: Panuntun Daniel Fajar , Alakaman Marlen Tineke , Sembiring Raharja 
Published: November 2024

Abstract
Is it possible to overcome the inclination of a victim of violence to become a perpetrator? The objective of the article is to present a conceptual framework for a community that has the potential to interfere with the continuing cycle of violence in situations where the victim transitions into the perpetrator. We can address these inquiries by discussing providence Theology, vulnerable communities, trauma survivors, and the act of remembering to establish connections between these three aspects. Providence Theology embodies the Christian community as a person’s providence capable of imagining the past, remembering the future, and enacting the present as a vulnerable community. Ultimately, we designate the concept as the vulnerable providence community by linking the imagination of past events with remembering God’s future providence to enact the present and break out from the cycle of violence.
Diabolus in Machina? Complex Digital Systems Interpreted through Early Modern Demonology
Authors: Wiesenfeldt Gerhard , Sinanan Jolynna 
Published: November 2024

Abstract
Based on the characterisation of complex technology as inherently magical, we interpret the engagement with digital systems within the framework of medieval and early modern demonological thought. By presenting a historicising argument that demonic understandings are inherent to the navigation of technological systems, we provide an ontological approach to the debate on the intentionality of technology. In the demonological vision of technology, we engage in digital systems beyond our control, producing moral dilemmas stemming from our inability to clearly discern good and evil demons – the invisible control of our digital lives and the irresponsible transgression of our expertise in decision making. Our trust in the digital systems we engage with, but do not control, is based on faith in the benevolence of demons. We argue that the attribution of intentionality to complex digital systems is unavoidable, even though it may be misguided. Using the epistemological framework of demonology enables us to better understand the consequences and functions of such attributions. This in turn provides a new perspective on the morality and agency of technological systems.
No Home Field Advantage: Themes in Journalistic Coverage of Western Visitors to Qatar for the 2022 World Cup
Authors: Moore Rick Clifton 
Published: November 2024

Abstract
This study expands upon research examining how journalists describe the cultural clashes between Islam and “the West.” Much of the recent scholarship in this area has focused on how media represent Muslim immigration to European and North American countries. In contrast, this investigation analyzes media portrayals of Islam within the framework of Western tourists visiting Qatar for the fifa World Cup. Using qualitative analysis, I examine three themes Western journalists used in describing conflicts presumed to occur when Western soccer fans visit a Muslim-majority country. While the themes might suggest a continued vision of a clash of civilizations, there was little in the news reports that suggested blatant Islamophobia. In fact, the findings hint that the modern West might sometimes treat the Muslim faith in a way that does not reveal open hostility, but subtly chips away at some of the distinctiveness of the religion.