bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kept in the Dark: Exploring Children’s Preparation for Parental Incarceration and Reentry
Authors: Young Diane S. , Smith Carrie Jefferson 
Published: October 2018

Background:Parental incarceration is a challenging and pivotal experience for families. Efforts to prepare children can hinder or promote children’s abilities to adapt.Objective:This study addresses the research question: How informed and prepared are children for parental incarceration, family reentry, and re-incarceration?Methods:Fourteen young adults shared their experiences related to childhood parental incarceration and family reentry through individual interviews.Findings:Regardlessof the parent’s stage of criminal justice involvement – arrest,incarceration, reentry, or re-incarceration, participants reported receiving very little information about what was taking place, why, or what they could expect.Conclusions:Small efforts to prepare and inform children were perceived to be helpfulas children. Resources and brief interventions that mitigate this experience of being kept in the dark are described.
Руска национална библиотека у Санкт-Петербургу: историјат, организација и колекције публикација
Authors: Ђурашиновић Биљана 
Published: October 2018

У раду су описани историјат и делатност Руске националне библиотеке у Санкт-Петербургу, која је, кроз више од две стотине година постојања, у различитим друштвено-политичким околностима (од периода Царства до савременог доба), била једна од најзначајнијих установа културе. Иако је њен национални карактер био дефинисан одмах након оснивања, од краја 19. века она свој рад није темељила само на очувању најзначајнијих споменика руске историје и културе, већ и баштине целог света. Књижне колекције Библиотеке представљене су кроз опис најзначајнијих дела из различитих крајева света. За српску културу посебну вредност представљају неки од најстаријих сачуваних примерака српских средњовековних рукописа (Вуканово јеванђеље, Мирослављево јеванђеље и Радослављево јеванђеље).Поред националне библиотеке у раду је сажето представљен и развој других типова библиотека у Русији, установљених углавном у 18. веку.
Pendampingan Desain Layanan Madrasah berbasis Website pada YPI Nahdlotusy Syubban
Authors: Anwar Edi Daenuri 
Published: October 2018

<p>Community service has been done to the subject YPI Nahdlotusy Syubban Sarimulyo Winong. This foundation oversee its four units of education; TPQ / Madin, RA, MI and MTs. The approach on this research is partipatory action research/PAR. The focus in this community service is designing website to all unit if servicesof madrasah atYPINahdlotusy Syubban.With the approach of PAR it is expected the participants cooperate to make changes, to solve the existing problems.The Research is divided into three stages, mapping, acting and evaluatiing. The results of mapping been succeeded by sharing between researchers, the head of TPQ/ Madin, RA, MI and MTs and the head of Yayasan foundation. Finally website service with name www.yapinasya-pati.sch.id succesfully formed. The next stage is conducting workshop with the expert of designing web. The participants are the head of all each unit, admin of any units and several teachers. The output of this workshop is all participants have proficient in the management of the web.</p><p> </p><p>Pengabdian dengan subjek Yayasan Pendidikan Islam (YPI) Nahdlotusy Syubban Sarimulyo Winong Pati telah terlaksana. Yayasan ini menaungi empat unit pendidikan yaitu TPQ/Madin, RA, MI dan MTs. Pendekatan yang digunakan dalam pengabdian ini yaitu PAR ( partipatory action research). Fokus dampingan dalam pengabdian ini adalah desain website untuk layanan madrasah dari unit-unit YPI Nahdlotusy Syubban. Dengan pendekatan PAR diharapkan Subjek dampingan melakukan perubahan untuk memecahkan solusi dari problem yang ada. Pengabdian ini terbagi menjadi 3 tahap yaitu mapping lokasi, tindakan dan evaluasi. Hasil mapping lokasi yang dilanjutkan melalui sharing antara peneliti, kepala sekolah setiap unit YPI Nahdlotusy Syubban meliputi TPQ/Madin, RA, MI dan MTs beserta pengurus yayasan. Akhirnya diusulkan dibentuklah website layanan dengan nama www.yapinasya-pati.sch.id sebagai web layanan madrasah.Kemudian dilanjutkan tindakan berupa workshop dengan narasumber ahli desain web dan peserta masing kepala masing-masing unit, admin dari setiap unit dan beberapa guru. Output workshop berupa admin website dari masing-masing unit sudah mahir dalam manajemen web.</p>
Elucidation of Malaria on Metabolic Activities During Pregnancy
Authors: Baloch Saira , Pei Xiaofang , Chen Jiayi , Chen Yuhang , Muhammad Shafi , He Fangting , Ke Dong 
Published: October 2018

Background:Malaria is extended to more than 90 countries of the world, and is also considered as a major public health and socio-economical problem.Objective:The aim of this study is the elucidation of malaria on metabolic activities in pregnancy.Material and Methods:A total of 60 patients with gestational vivax malaria were recruited in this study, and 60 healthy pregnant women were selected as a control group. These women were selected using simple random sampling technique. A sample of 5 ml venous blood was drawn from each patient, centrifuged at 5000 rpm for 20 minutes to separate the serum. The serum samples were analyzed for enzyme activity such as Alkaline Phosphatase (ALP), Creatine Phospho Kinase (CPK), Lactate Dehydrogenase (LDH), and Serum Glutamic Oxaloacetic Transaminase / aspartate aminotransferase (SGOT/AST) by using kit method on Microlab 300 and trace metal content Magnesium, Iron, Copper and Zinc (Mg, Fe, Cu, and Zn) by Atomic Absorption Spectroscopy (Varian AAS Model A-20).Results:There was an increased level of Alkaline Phosphatase (ALP), Creatine Phospho Kinase (CPK), Lactate Dehydrogenase (LDH), and Serum Glutamic Oxaloacetic Transaminase / aspartate aminotransferase in sixty pregnant women suffering from vivax malaria as compared to the control subjects. Whereas, the low concentrations of serum iron, copper, magnesium and zinc were observed in patients as compared to the control subjects.Conclusion:The findings of this study suggest that in order to enhance the immunity and develop resistance towards malaria during pregnancy, it is necessary to balance enzyme activity and provide diverse metals in the therapy to cure this disease.
Design, Synthesis and Anticancer Evaluation of Novel Series of Indibulin Analogues
Authors: Moghadam Ebrahim S. , Saravani Farhad , Ostad Seyednasser , Tavajohi Shohreh , Hamedani Morteza P. , Amini Mohsen 
Published: October 2018

Background:
Cancer is an important cause of human death worldwide. During the last
decades, many anticancer agents with anti-tubulin mechanism have been synthesized or extracted
from nature and some of them also entered clinical use. Indibulin is one of the most potent tubulin
polymerization inhibitors with minimal peripheral neuropathy, which is a big problem by some of
the antimitotic agents such as taxanes and vinka alkaloids. With respect to this giant benefit, herein
we decided to design and synthesize novel indibulin related compounds and investigate their
anticancer activity against HT-29, Caco-2 and T47-D cancerous cell lines as well as NIH-T3T as
normal cell line.

Objective:
The aim of this study was to synthesize new anti-cancer agents and evaluates their cytotoxic
activity on diverse cancerous and normal cell lines.

Method:
Target compounds were synthesized in multistep reaction and cytotoxic activity was
investigated by MTT cell viability assay.

Results:
Herein, nine novel target compounds were synthesized in moderate to good yield. Some
of the compounds exerted good cytotoxic activity against cancerous cell lines. Annexin V/PI staining
showed that compound 4g could induce apoptosis and necrosis in HT-29 cell line.

Conclusion:
It is valuable to do further investigation on compound 4g which showed the highest
activity against HT-29 and Caco-2 (IC50 values are 6.9 and 7 &µM respectively). Also, synthesis of
new derivatives of current synthesized compounds is suggested.
Substance Use in Adolescents Presenting to the Emergency Department
Authors: Onigu-Otite Edore , Kurtzweil Miju , Tucci Veronica , Moukaddam Nidal 
Published: October 2018

Background:
Adolescent substance use is a dynamic public health problem.
Adolescence is a unique developmental period involving overlapping biological,
psychological, and social factors which increase the rates of initiation of substance use. The
developing adolescent brain is particularly susceptible to the effects of substances and most
adults with substance use disorders began to have symptoms and problems in their
adolescent years. Yet, for various reasons, most adolescents who use, misuse, abuse, or are
addicted to substances do not perceive the need for treatment.

Objective:
Drug and alcohol use among adolescents is a common presentation in hospital
Emergency Departments (EDs) and presents in different forms including in association with
intoxication, withdrawal states, or trauma associated with drug-related events. For many
adolescents with substance use, the Emergency Department (ED) is the first point of contact
with medical personnel and thus also serves as a potential entry point into treatment.

Methods:
This article reviews the common ways drug and alcohol problems present in the
ED, clinical assessment of the patient and family, screening, laboratory testing, brief
interventions in the ED, and referral to treatment beyond the ED.

Conclusion:
Guidelines on how to manage the shifting terrain of adolescent substance use
presenting in EDs across the nation continue to evolve. We highlight that considerable
further research is needed to inform effective ED protocols to address this important
individual and public health safety concern. Systems of care models which include
collaborative teams of diverse stake holders are needed to effectively manage adolescents
with substance use disorders.
Pengembangan multimedia pembelajaran interaktif IPA untuk meningkatkan pemahaman siswa pada materi Mikroorganisme SMP
Authors: Hotimah Hotimah , Muhtadi Ali 
Published: October 2018

Penelitian ini bertujuan: (1) untuk menghasilkan multimedia pembelajaran interaktif IPA pada materi mikroorganisme yang layak di SMP, dan (2) untuk mengetahui kelayakan multimedia pembelajaran interaktif IPA dalam peningkatan pemahaman siswa pada materi mikroorganisme. Penelitian pengembangan ini mengacu pada langkah yang dikembangkan oleh Alessi & Trollip. Desain pengembangan dikelompokkan menjadi tiga tahapan prosedur pengembangan, yang meliputi: (a) perencanaan, (b) desain, dan (c) pengembangan. Hasil penelitian menunjukkan hasil sebagai berikut. (1) Ahli materi menilai aspek pembelajaran dan aspek materi dengan kategori baik (skala 4,15), ahli media menilai aspek media dengan kategori baik (skala 4,2), dan siswa (pengguna) menilai aspek pembelajaran, aspek materi, dan aspek media dengan kategori sangat baik (skala 4,5), sehingga dapat disimpulkan bahwa produk multimedia pembelajaran interaktif ini dinilai layak digunakan siswa SMP. (2) Hasil uji coba lapangan (hasil pretes dan postes) menunjukkan bahwa multimedia interaktif IPA ini dapat meningkatkan pemahaman siswa pada materi mikroorganisme.Kata kunci: multimedia pembelajaran interaktif, mikroorganisme DEVELOPING INTERACTIVE MULTIMEDIA TO IMPROVING LEARNERS' UNDERSTANDING ON THE MICROORGANISMS TOPIC IN JUNIOR HIGH SCHOOLAbstractThis research aims to: (1) to produce an appropriate interactive learning multimedia of science for teaching on the microorganisms topic, for Junior High School students, and (2) to reveal the appropriate of interactive learning multimedia of science designed for teaching, toward the students understanding on the microorganisms topic. This development research refers to the stages developed by Alessi & Trollip. The development design used in this research is divided into 3 stages namely: (a) planning, (b) designing, and (c) developing. The results show the following results. (1) The material expert assessed the aspects of learning and material aspects with good category (scale 4.15), the media experts judged the aspects of the media in good category (scale 4.2), and students (user) assessed the aspects of learning, material, and media aspects with very good category (scale 4.5). Results suggest that interactive learning multimedia are considered good as a learning material for junior high school students. (2) The results of field trials (pretest and post test results) show that this medium is appropriate for improving learners' understanding on the microorganism topic.Keywords: interactive learning multimedia, microorganisms
Peningkatkan interaktivitas pembelajaran melalui penggunaan komunikasi asynchronous di Universitas Negeri Yogyakarta
Authors: Wahyuningsih Dian , Sungkono Sungkono 
Published: October 2018

Penelitian ini bertujuan untuk meningkatkan interaktivitas pembelajaran melalui penggunaan komunikasi asynchronous di Universitas Negeri Yogyakarta. Penelitian tindakan kelas ini dilaksanakan dalam dua siklus. Subjek penelitian ini adalah 32 orang mahasiswa Program Studi Teknologi Pendidikan UNY, yang menempuh mata kuliah Pengembangan E-learning Berbasis Web pada tahun ajaran 2015/2016. Data dikumpulkan menggunakan teknik wawancara, check list, dan dokumentasi, serta dianalisis secara deskriptif melalui teknik persentase. Hasil penelitian menunjukkan bahwa meningkatkan interaktivitas pembelajaran melalui penggunaan komukasi asynchronous pada mata kuliah pengembangan e-learning berbasis web di Prodi TP UNY dilakukan melalui 4 hal bahwa komunikasi asynchronous: (1) diterapkan secara konsisten pada mata kuliah e-Learning Berbasis Web, (2) digunakan menancap (embed) pada e-LearningUNY (Besmart), (3) dimanfaatan untuk menyelesaiakn tugas yang memerlukan kolaborasi, dan (4) menggunakan tipe yang berfariasi. Interaktivitas pembelajaran mahasiswa sebelum diterapkan komunikasi asynchronous berada di kategori sangat rendah dengan persentase 35%. Terjadi peningkatan interaktivitas pembelajaran mahasiswa setelah diterapkan komunikasi asynchronous di siklus pertama pada kategori rendah dengan persentase 60%, dan kembali meningkat di siklus kedua pada kategori sangat tinggi dengan persentase 82,33%.Kata kunci: interaktivitas pembelajaran, komunikasi asynchronous IMPROVING LEARNING INTERACTIVITY BY IMPLEMENTING ASYNCHRONOUS COMMUNICATION IN YOGYAKARTA STATE UNIVERSITYAbstractThis research aims to improve learning interactivity by asynchronous communication in web based e-learning development course. This study used a classroom action research (CAR) which is conducted in two cycles. The subjects were 32 students of Curriculum and Educational Technology Department Yogyakarat State University (YSU) who participated in the web based e-learning development course in academic year 2015/2016. The data were collected using percentage method by interview, check list and documentation. The result shows that, improving instructional interactivity by asynchronous communication in web based e-learning development course were conducted using four strategies, i.e: 1) asynchronous communication applied consistently on Web-based e-Learning courses, 2) embedding on e-Learning of Yogyakarta State University (Besmart), 3) utilized for completion of tasks that require collaboration, and 4) using a varied type of asynchronous mode. Learning interactivity was reach 35 % in a very low category before asynchronous communication were implemented. The result shows in the 1st cycle, instructional interactivity rose up to 60% in a low category. In the 2nd cycle, it provides dramatically improvement up to 82,33% in very high category.Keywords: instructional interactivity, asynchronous communication
Quality of HIV Websites With Information About Pre-Exposure Prophylaxis or Treatment as Prevention for Men Who Have Sex With Men: Systematic Evaluation
Authors: Silverman Taylor , Asante Nicole , van den Berg Jacob J 
Published: October 2018

Background
Knowledge and uptake of high-efficacy HIV prevention strategies such as pre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) remain low among men who have sex with men (MSM) who are at the highest risk for HIV infection in the United States. Electronic health (eHealth) interventions are promising tools for disseminating information about these critical yet underutilized strategies and addressing key barriers to uptake among target populations. However, existing HIV prevention websites are understudied and unevaluated.

Objective
This study aimed to systematically review and evaluate existing HIV websites that include information about PrEP or TasP for MSM.

Methods
From March 2018 to May 2018, 2 trained research assistants (RAs) entered relevant key words and phrases into 3 commonly used search engines and applied exclusion criteria to all returned results to identify 31 websites included in this review. RAs independently scored each website for authority, usability, interactivity, and PrEP/TasP-related content based on a standardized rating scale and then averaged the results.

Results
No website received a perfect score in any of the 4 categories, and the average website score was 62% (37/60). Less than a quarter of the websites (23%, 7/31) received a score of more than 75% (7.5/10) for content. Approximately two-thirds of the websites (65%, 20/31) received a score of 50% (5/10) or lower for interactivity. The average score in usability was 68% (6.8/10) and in authority was 69% (6.9/10). Other deficiencies observed included difficulty locating relevant content and lack of information targeting audiences with the highest likelihood of HIV infection.

Conclusions
Existing HIV prevention websites with information about PrEP or TasP for MSM fail to provide adequate content as well as present that content to users in an interactive and audience-conscious way. Future eHealth interventions should attempt to rectify these deficiencies to successfully engage and educate MSM at high risk for HIV regarding prevention strategies.
Principles of Textual Rhetoric in CakCuk Discourse
Authors: Subiyatningsih Foriyani 
Published: October 2018

This research aims to study how the creator of CakCuk creates language based on the principles and maxims of textual rhetoric in CakCuk designs. The data was collected using a method of observation, with a basic technique of recording followed by a technique of note-taking. The data analysis used a method of distribution, comparison, and contextual identity. The results of this study show that CakCuk discourse is a product of the language creativity of its creator through the utilization of principles or maxims of textual rhetoric. The key to this creativity is the creator’s ability to use maxims in order to achieve efficiency, clarity, effectiveness, and attractiveness in the text. The motivation underlying the choice of principles/maxims is: (i) the principle of processability in order to determine the main focus and weighting of the text; (ii) the principle of clarity in order to make the message clear; (iii) the principle of economy in order to keep the text as short as possible; (iv) the principle of expressiveness in order to make the text effective.
Daya Vermisidal Ekstrak Lima Jenis Etnofarmakologi terhadap Cacing Haemonchus contortus Secara In-vitro
Authors: Wirawan I Gusti Komang Oka , Kurniasih Kurniasih , Prastowo Joko , Nurcahyo Wisnu 
Published: October 2018

Research aimed to identify the most effective concentration of five extract types (EKBMCP, EKPAS, EDMSP, EBJCP, dan EDMCO) as vermicidal anthelmintic against H. contortus in-vitro. Research was consisted of seven groups, among them five groups were considered as treatment groups that named based on the extract type (EKBMCP, EKPAS, EDMSP, EBJCP, dan EDMCO). Each treatment group was consisted five subgroups of etnopharmacological concentration : 0,5%, 1,5%, 2,5%, 3,5% dari 0,2 g/mL. Other two group were regarded as a negative control by distilled water treatment, and a positive control by pyrantel pamoat 5%. Every single treatment group was quadruplet and exposure each concentration were performed in quadruplet with variation in exposure times i.e. : 1, 3, 5, and 7 hours. The research focused on several variables that were the percentage of live and dead H. contortus in the treatment groups, extract concentration, and treatment period by using selected etnopharmacological extract. The effective vermicidal anthelmentic concentration of each treatment was analyzed descriptively. The results showed that five etnopharmacological extract types that were EKBMCP, EKPAS, EDMSP, EBJCP, dan EDMCO had a potency as vermicidal anthelmentic. Among those treatment, EKPAS and EBJCP had the lowest concentration (2,5%) to produce optimum vermicidal effect (100%) with period five hours exposure. Other treatment groups with EKBMCP and EDMSP needed 3,5% concentration with exposure period seven hours to produce optimum vermicidal effect, respectively. Another treatment group with EDMCO needed 3,5% concentration with exposure time seven hours to produce optimum vermicidal effect.
AS INUNDAÇÕES DE 2009 NA AMAZÔNIA E SUAS RELAÇÕES COM O DESENVOLVIMENTO SUSTENTÁVEL: IMPACTOS AO PRODUTO INTERNO BRUTO MUNICIPAL
Authors: Nina Alex Santiago , Szlafsztein Cláudio Fabian 
Published: October 2018

Nos últimos anos, tem aumentado a frequência dos desastres naturais na Amazônia, concomitantemente com a necessidade de estimar os seus prejuízos econômicos. Este trabalho tem como objetivo verificar qual é o tipo e a intensidade do impacto das inundações de 2009, consideradas as maiores já registradas na Amazônia, no crescimento do Produto Interno Bruto (PIB) municipal. A metodologia consistiu na análise de correlação linear entre o desempenho econômico e algumas variáveis referentes ao tipo de inundação e indicadores socioeconômicos. Os resultados mostram que as inundações bruscas são as mais problemáticas em longo prazo. As principais estratégias a serem adotadas perpassam pela inclusão de ações de mitigação de desastres naturais ao planejamento do desenvolvimento sustentável da Amazônia. Palavras-chave: Produto Interno Bruto. Inundação. Amazônia. THE 2009 FLOODS IN THE AMAZON AND ITS RELATIONSHIP WITH SUSTAINABLE DEVELOPMENT: IMPACT ON THE MUNICIPAL GROSS DOMESTIC PRODUCT Abstract: In the last years, have been increase the frequency of natural disasters in Amazon, concomitantly whit the need of estimate their economic losses. This work have the objective of check what is the type and intensity of 2009 floods impacts, considered the major already registered in Amazon, to the increase of municipal Gross Domestic Product (GDP). The methodology was the linear correlation analysis between the economic performance and some variable relative to inundation type and socioeconomics indicators. The results bring which the fast floods are the major problem in the long term. The means strategies to be adopted are the inclusion of natural disasters mitigation actions in plan of sustainable development of Amazon. Keywords: Gross Domestic Product. Flood. Amazon. LAS INUNDACIONES DE 2009 EN LA AMAZONÍA Y SU RELACIÓN CON EL DESARROLLO SOSTENIBLE: IMPACTO EN EL PRODUCTO INTERNO BRUTO MUNICIPAL Resumen: En los últimos años ha aumentado la frecuencia de los desastres naturales en la Amazonia, concomitantemente con la necesidad de estimar sus prejuicios económicos. Este trabajo tiene como objetivo verificar cual es el tipo y la intensidad del impacto de las inundaciones de 2009, consideradas las mayores ya registradas en la Amazonia, al crecimiento del Producto Bruto Interno (PBI) municipal. La metodología consistió el análisis de correlación linear entre el desempeño económico y algunas variables referentes al tipo de inundación e indicadores socioeconómicos. Los resultados muestran que las inundaciones bruscas son las mas problemáticas a largo plazo. Las principales estrategias a ser adoptadas pasan por la inclusión de acciones de mitigación de desastres naturales a la planificación del desarrollo sostenible de la Amazonia. Palabras clave: Producto Interno Bruto. Inundaciones. Amazonia.