bluuebunny/crossref_metadata_2025_split huggingface dataset:
Viajar con la tradición: Los pescadores artesanales ante la pesca-turismo en la Comunidad Valenciana (España)
Authors: Herrera-Racionero Paloma , Miret-Pastor Luis , Lizcano Emmánuel 
Published: June 2018

<p>A pesar del potencial de los puertos españoles, la pesca-turismo no acaba de implantarse en nuestro país. Solucionados, en principio, los problemas legislativos, la actitud de los pescadores frente a esta actividad parece uno de los asuntos clave que determinará su éxito o fracaso. Este trabajo se centra en analizar la percepción que los pescadores tienen de la pesca-turismo, concretamente, en las oportunidades y amenazas que perciben. Para ello se ha llevado a cabo un estudio cualitativo basado en el análisis en profundidad de 32 entrevistas a pescadores de la Comunidad Valenciana (España). </p>
Los Baños de Mula (Murcia): Un entorno rural en declive. Propuestas patrimoniales y didácticas
Authors: López Fernández José Antonio , Canales Martínez Gregorio , Vera Muñoz María Isabel 
Published: June 2018

<p>El entorno rural de Los Baños, pedanía del municipio de Mula (Región de Murcia) presenta un claro declive demográfico y económico. Uno de los principales factores de este proceso reside en la escasa actualización del uso de sus aguas termales, dispuestas tradicionalmente en paradores y casas de baños de forma independiente. Sin embargo, la singularidad patrimonial de su arquitectura urbana e hidráulica, los recursos arqueológicos y naturales que circundan el área, además de la importancia actual del turismo de salud, son aspectos a tener en cuenta en la promoción y desarrollo de este territorio. En este trabajo se proponen una serie de actuaciones que podrían mejorar notablemente la situación social y económica de este paraje tan atractivo y único. </p>
Las romerías, oportunidad turística y relaciones sociales entre locales y visitantes. El caso de la Cerdanya en Cataluña
Authors: Prat Forga José María , Cànoves Valiente Gemma 
Published: June 2018

<p>En los estos últimos años se están desarrollando nuevas actividades alrededor del turismo cultural-religioso con el objetivo de dar a conocer y mantener vivo el folklore propio de las generaciones pasadas. Entre estos fenómenos histórico-culturales y turísticos están las romerías. Se trata de excursiones grupales, generalmente a pie, a ermitas y santuarios donde, además de las actividades puramente religiosas, también se aprovecha para realizar otros actos festivos vinculados con las tradiciones del lugar. De este modo, con las romerías, algunos lugares religiosos en los territorios de interior se han convertido en puntos de encuentro entre los turistas y la población local, con una triple función: revalorizar el patrimonio local, atraer visitantes y ser lugar de encuentro entre la comunidad local y los turistas. En este trabajo, a partir de documentación y estadísticas sobre el tema y de entrevistas a participantes, se ha analizado el caso de las romerías en la Cerdanya española (los llamados “aplecs”), y se ha confirmado que se trata de unos eventos populares que permiten revalorizar turísticamente el territorio, ayudando a reafirmar la identidad local, conservando el patrimonio material e inmaterial y favoreciendo las relaciones sociales entre gente con diferentes intereses y motivaciones. </p>
Equal Education, Unequal Jobs: College and University Students with Disabilities
Authors: Stewart Jennifer M. , Schwartz Saul 
Published: June 2018

Are students with a permanent disability more likely to drop out of post-secondary education than students without a permanent disability? Once they are out of postsecondary education, do their experiences in the labour market differ? Answers to these questions are necessary to evaluate current policies and to develop new policies.
This paper addresses these two questions using a unique data set that combines administrative records from the Canada Student Loans Program with survey responses. Our measure of permanent disability is an objective one that requires a physician’s diagnosis. The survey data supply information on the students’ education and labour market status.
Simple descriptive statistics suggest that, compared to students without a permanent disability, students with a permanent disability are equally likely to drop out of postsecondary education, but less likely to be in the labour force and more likely to be unemployed. We use propensity score matching to address potential selection into the group of students who documented their disability. The results using propensity score matching are consistent with the descriptive statistics.
Our story is one of an underpublicized success—the rising number of students with disabilities in postsecondary institutions and their equal likelihood of graduation—and a persistent problem—the continued disadvantage that people with disabilities, even those with the same educational attainment as people without disabilities, face in the labour market.
The impact of the Wenchuan earthquake on early puberty: a natural experiment
Authors: Lian Qiguo , Zuo Xiayun , Mao Yanyan , Zhang Yan , Luo Shan , Zhang Shucheng , Lou Chaohua , Tu Xiaowen , Zhou Weijin 
Published: June 2018

BackgroundThe factors influencing pubertal timing have gained much attention due to a secular trend toward earlier pubertal onset in many countries. However, no studies have investigated the association between the Great earthquake and early puberty. We aimed to assess whether the Wenchuan earthquake is associated with early puberty, in both boys and girls.MethodsWe used data from two circles of a survey on reproductive health in China to explore the impact of the Wenchuan earthquake on early puberty , and a total of 9,785 adolescents (4,830 boys, 49.36%) aged 12–20 years from 29 schools in eight provinces were recruited. Wenchuan earthquake exposure was defined as those Sichuan students who had not experienced oigarche/menarche before May 12, 2008. Early puberty was identified as a reported onset of oigarche/menarche at 11 years or earlier. We tested the association between the Wenchuan earthquake and early puberty in boys and girls. Then, subgroup analysis stratified by the age at earthquake exposure also was performed.ResultsIn total, 8,883 adolescents (4,543 boys, 51.14%) with a mean (SD) age of 15.13 (1.81) were included in the final sample. In general, children exposed to the earthquake had three times greater risk of early puberty (boys, RR [95% CI] = 3.18 [2.21–4.57]; girls: RR [95%CI] =3.16 [2.65–3.78]). Subgroup analysis showed that the adjusted RR was 1.90 [1.19–3.03] for boys and 2.22 [1.75–2.80] for girls. Earthquake exposure predicted almost a fourfold (RR [95%CI] = 3.91 [1.31–11.72]) increased risk of early puberty in preschool girls, whereas the increase was about twofold (RR [95%CI] = 2.09 [1.65–2.64]) in schoolgirls. Among boys, only older age at earthquake exposure was linked to early puberty (RR [95%CI] = 1.93 [1.18–3.16]).ConclusionsWenchuan earthquake exposure increased the risk of early puberty in boys and girls, and preschoolers were more at risk than schoolchildren. The implications are relevant to support policies for those survivors, especially children, to better rebuild after disasters.
Bibliometric analysis of research on the role of intestinal microbiota in obesity
Authors: Yao Haiqiang , Wan Jin-Yi , Wang Chong-Zhi , Li Lingru , Wang Ji , Li Yingshuai , Huang Wei-Hua , Zeng Jinxiang , Wang Qi , Yuan Chun-Su 
Published: June 2018

Background
Obesity is a key public health problem. The advancement of gut microbiota research sheds new light on this field. This article aims to present the research trends in global intestinal microbiota studies within the domain of obesity research.

Methods
Bibliographic information of the publications on intestinal microbiota and obesity was retrieved from the Scopus database, and then analyzed by using bibliometric approaches.

Results
A total of 3,446 references were retrieved; the data indicated a steady growth and an exponential increase in publication numbers. The references were written in 23 different languages (93.8% in English). A number of 3,056 English journal papers were included in the further analyses. Among the 940 journals, the most prolific ones were PLOS ONE, Scientific Reports, and British Journal of Nutrition. North America and Europe were the highest publication output areas. The US (995 publications) ranked first in the number of publications, followed by the China (243 publications) and France (242 publications). The publication numbers were significantly correlated with gross domestic product (GDP), human development index (HDI), and population number (PN). International collaboration analysis also shows that most of the collaborations are among developed countries.

Discussion
This comprehensive bibliometric study indicates that gut microbiota is a significant topic in the obesity research. The structured information may be helpful in understanding research trends, and locating research hot spots and gaps in this domain.
Achilles and tail tendons of perlecan exon 3 null heparan sulphate deficient mice display surprising improvement in tendon tensile properties and altered collagen fibril organisation compared to C57BL/6 wild type mice
Authors: Shu Cindy C. , Smith Margaret M. , Appleyard Richard C. , Little Christopher B. , Melrose James 
Published: June 2018

The aim of this study was to determine the role of the perlecan (Hspg2) heparan sulphate (HS) side chains on cell and matrix homeostasis in tail and Achilles tendons in 3 and 12 week oldHspg2exon 3 null HS deficient (Hspg2Δ3 − ∕Δ3 −) and C57 BL/6 Wild Type (WT) mice. Perlecan has important cell regulatory and matrix organizational properties through HS mediated interactions with a range of growth factors and morphogens and with structural extracellular matrix glycoproteins which define tissue function and allow the resident cells to regulate tissue homeostasis. It was expected that ablation of the HS chains on perlecan would severely disrupt normal tendon organization and functional properties and it was envisaged that this study would better define the role of HS in normal tendon function and in tendon repair processes. Tail and Achilles tendons from each genotype were biomechanically tested (ultimate tensile stress (UTS), tensile modulus (TM)) and glycosaminoglycan (GAG) and collagen (hydroxyproline) compositional analyses were undertaken. Tenocytes were isolated from tail tendons from each mouse genotype and grown in monolayer culture. These cultures were undertaken in the presence of FGF-2 to assess the cell signaling properties of each genotype. Total RNA was isolated from 3–12 week old tail and Achilles tendons and qRT-PCR was undertaken to assess the expression of the following genesVcan, Bgn, Dcn, Lum, Hspg2, Ltbp1, Ltbp2, Eln and Fbn1.Type VI collagen and perlecan were immunolocalised in tail tendon and collagen fibrils were imaged using transmission electron microscopy (TEM). FGF-2 stimulated tenocyte monolayers displayed elevatedAdamts4,Mmp2, 3, 13 mRNA levelscompared to WT mice. Non-stimulated tendonCol1A1, Vcan, Bgn, Dcn, Lum, Hspg2, Ltbp1, Ltbp2, Eln and Fbn1 mRNA levelsshowed no major differences between the two genotypes other than a decline with ageing while LTBP2 expression increased. Eln expression also declined to a greater extent in the perlecan exon 3 null mice (P < 0.05). Type VI collagen and perlecan were immunolocalised in tail tendon and collagen fibrils imaged using transmission electron microscopy (TEM). This indicated a more compact form of collagen localization in the perlecan exon 3 null mice. Collagen fibrils were also smaller by TEM, which may facilitate a more condensed fibril packing accounting for the superior UTS displayed by the perlecan exon 3 null mice. The amplified catabolic phenotype ofHspg2Δ3 − ∕Δ3 −mice may account for the age-dependent decline in GAG observed in tail tendon over 3 to 12 weeks. After Achilles tenotomyHspg2Δ3 − ∕Δ3 −and WT mice had similar rates of recovery of UTS and TM over 12 weeks post operatively indicating that a deficiency of HS was not detrimental to tendon repair.
Holographic Recording and Hierarchical Surface Patterning on Periodic Submicrometer Pillar Arrays of Azo Molecular Glass via Polarized Light Irradiation
Authors: Hsu Chungen , Xu Zeda , Wang Xiaogong 
Published: June 2018

AbstractPeriodic submiocrometer pillar arrays are fabricated from a photoresponsive azo molecular glass (IA‐Chol) by soft‐lithographic hot embossing with elastomeric poly(dimethylsiloxane) (PDMS) modes. Through deformation of each submicrometer‐sized pillar in response to the local amplitude and polarization of the superimposed electric waves, optical holograms are recorded on the IA‐Chol pillar arrays. When the interference pattern is formed by two polarized beams with opposite‐circular polarizations, the recorded patterns mainly reflect the polarization state variations with spatial phase difference of the interfering waves. When two plane waves with the same linear polarizations are superimposed, where the polarization direction is almost the same as the writing beams, the intensity variation of the superimposed electric waves is recorded by the pillar arrays changing spatially with the phase variations. Various ordered surface patterns with distinct hierarchical configurations are successfully developed by the intensity and polarization modulations of the interfering waves. This approach not only allows to directly visualize the intensity and polarization of the coherent light captured by the holograms, but also provides a powerful platform to fabricate various complex surface patterns. The submicrometer pillar arrays can also be used to record polarization hologram and the images are reconstructed by reference light in diffracted spots.
Dopant‐Free Hydrogels with Intrinsic Photoluminescence and Biodegradable Properties
Authors: Tsou Yung‐Hao , Zhang Xue‐Qing , Bai Xin , Zhu He , Li Zhongyu , Liu Yanlan , Shi Jinjun , Xu Xiaoyang 
Published: June 2018

AbstractPhotoluminescent hydrogels that function as both injectable scaffolds and fluorescent imaging probes hold great potential for therapeutics delivery and tissue engineering. Current fluorescent hydrogels are fabricated by either conjugating or doping a fluorescent dye, fluorescent protein, lanthanide chelate, or quantum dot into polymeric hydrogel matrix. Their biomedical applications are severely limited due to drawbacks such as photostability, carcinogenesis, and toxicity associated with the above‐mentioned dopants. Here, a successful development of dopant‐free photoluminescent hydrogels in situ formed by crosslinking of biocompatible polymer precursors is reported, which can be synthesized by incorporating an amino acid to a citric acid based polyester oligomer followed by functionalization of multivalent crosslinking group through a convenient transesterification reaction using Candida Antarctica Lipase B as a catalyst. It is demonstrated that the newly developed hydrogels possess tunable degradation, intrinsic photoluminescence, mechanical properties, and exhibit sustained release of various molecular weight dextrans. In vivo study shows that the hydrogels formed in situ following subcutaneous injection exhibit excellent biocompatibility and emit strong fluorescence under visible light excitation without the need of using any traditional organic dyes. Their in vivo degradation profiles are then depicted by noninvasively monitoring fluorescence intensity of the injected hydrogel implants.
Engineering the Future of Silk Materials through Advanced Manufacturing
Authors: Zhou Zhitao , Zhang Shaoqing , Cao Yunteng , Marelli Benedetto , Xia Xiaoxia , Tao Tiger H. 
Published: June 2018

AbstractSilk is a natural fiber renowned for its outstanding mechanical properties that have enabled the manufacturing of ultralight and ultrastrong textiles. Recent advances in silk processing and manufacturing have underpinned a re‐interpretation of silk from textiles to technological materials. Here, it is argued that silk materials—optimized by selective pressure to work in the environment at the biotic–abiotic interface—can be harnessed by human micro‐ and nanomanufacturing technology to impart new functionalities and opportunities. A critical overview of recent progress in silk technology is presented with emphasis on high‐tech applications enabled by recent innovations in multilevel modifications, multiscale manufacturing, and multimodal characterization of silk materials. These advances have enabled successful demonstrations of silk materials across several disciplines, including tissue engineering, drug delivery, implantable medical devices, and biodissolvable/degradable devices.
Silicon Oxide (SiOx): A Promising Material for Resistance Switching?
Authors: Mehonic Adnan , Shluger Alexander L. , Gao David , Valov Ilia , Miranda Enrique , Ielmini Daniele , Bricalli Alessandro , Ambrosi Elia , Li Can , Yang J. Joshua , Xia Qiangfei , Kenyon Anthony J. 
Published: June 2018

AbstractInterest in resistance switching is currently growing apace. The promise of novel high‐density, low‐power, high‐speed nonvolatile memory devices is appealing enough, but beyond that there are exciting future possibilities for applications in hardware acceleration for machine learning and artificial intelligence, and for neuromorphic computing. A very wide range of material systems exhibit resistance switching, a number of which—primarily transition metal oxides—are currently being investigated as complementary metal–oxide–semiconductor (CMOS)‐compatible technologies. Here, the case is made for silicon oxide, perhaps the most CMOS‐compatible dielectric, yet one that has had comparatively little attention as a resistance‐switching material. Herein, a taxonomy of switching mechanisms in silicon oxide is presented, and the current state of the art in modeling, understanding fundamental switching mechanisms, and exciting device applications is summarized. In conclusion, silicon oxide is an excellent choice for resistance‐switching technologies, offering a number of compelling advantages over competing material systems.
Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles
Authors: Myerson Jacob W. , Braender Bruce , Mcpherson Olivia , Glassman Patrick M. , Kiseleva Raisa Y. , Shuvaev Vladimir V. , Marcos‐Contreras Oscar , Grady Martha E. , Lee Hyun‐Su , Greineder Colin F. , Stan Radu V. , Composto Russell J. , Eckmann David M. , Muzykantov Vladimir R. 
Published: June 2018

AbstractMolecular targeting of nanoparticle drug carriers promises maximized therapeutic impact to sites of disease or injury with minimized systemic effects. Precise targeting demands addressing to subcellular features. Caveolae, invaginations in cell membranes implicated in transcytosis and inflammatory signaling, are appealing subcellular targets. Caveolar geometry has been reported to impose a ≈50 nm size cutoff on nanocarrier access to plasmalemma vesicle associated protein (PLVAP), a marker found in caveolae in the lungs. The use of deformable nanocarriers to overcome that size cutoff is explored in this study. Lysozyme‐dextran nanogels (NGs) are synthesized with ≈150 or ≈300 nm mean diameter. Atomic force microscopy indicates the NGs deform on complementary surfaces. Quartz crystal microbalance data indicate that NGs form softer monolayers (≈60 kPa) than polystyrene particles (≈8 MPa). NGs deform during flow through microfluidic channels, and modeling of NG extrusion through porous filters yields sieving diameters less than 25 nm for NGs with 150 and 300 nm hydrodynamic diameters. NGs of 150 and 300 nm diameter target PLVAP in mouse lungs while counterpart rigid polystyrene particles do not. The data in this study indicate a role for mechanical deformability in targeting large high‐payload drug‐delivery vehicles to sterically obscured targets like PLVAP.
Second Harmonic Generation in Atomically Thin MoTe2
Authors: Song Yu , Tian Ruijuan , Yang Jiulong , Yin Rui , Zhao Jianlin , Gan Xuetao 
Published: June 2018

AbstractOptical second harmonic generations (SHGs) from atomically thin MoTe2 flakes with 2H and 1T′ phases are studied. From 2H‐MoTe2 samples with odd (even) numbers of layers, strong (negligible) SHGs are observed due to the layer‐dependent broken inversion symmetry. When pumped by a telecom‐band laser, SHG from a monolayer 2H‐MoTe2 is about one order of magnitude stronger than that from a monolayer WS2; an extremely high second‐order nonlinear susceptibility of 2.5 nm V−1 is estimated, presenting the highest value among those reported in 2D materials. SHG measurements in MoTe2 are also demonstrated as an efficient way to distinguish the 2H‐to‐1T′ phase transition. Compared with the SHG in 2H‐MoTe2, 1T′‐MoTe2's SHG has much lower efficiency and the polarization dependence is changed from a six‐fold pattern to a two‐lobe pattern.
Phosphine‐Free NNN‐Manganese Complex Catalyzed α‐Alkylation of Ketones with Primary Alcohols and Friedländer Quinoline Synthesis
Authors: Barman Milan K. , Jana Akash , Maji Biplab 
Published: June 2018

AbstractHerein, we report a very simple and inexpensive catalytic system based on Earth's abundant transition metal manganese and on a bench‐stable phosphine‐free NNN‐pincer ligand for an atom‐efficient α‐alkylations of ketones with primary alcohols via hydrogen‐autotransfer C−C bond formation protocol. The precatalyst could be generated in situ and could be activated by using catalytic amount of base under milder conditions. A range of ketones were efficiently diversified with a broad range of primary alcohols in good to excellent isolated yields. Remarkably, this catalyst could also be employed for the synthesis of quinoline derivatives using 2‐aminobenzyl alcohol as an alkylating agent. The later reaction is highly benign producing only hydrogen and water as byproducts.magnified image
Integrating Solar Energy in Rome's Built Environment: A Perspective for Distributed Generation on Global Scale
Authors: Ciriminna Rosaria , Pecoraino Mario , Meneguzzo Francesco , Pagliaro Mario 
Published: June 2018

AbstractLarge‐scale integration of solar energy technologies in Rome's built environment epitomizes the needed general adoption of distributed generation via functionalization of buildings of all size and end use across the world, to become active energy generators and no longer energy users only. This essay identifies selected technology solutions and critical policy and educational initiatives to effectively achieve within the next decade (2018–2027) the widespread uptake of decentralized solar energy systems in the built environment on a global scale.