bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les histoires des marques sur leur site Internet : une histoire de transport narratif
Authors: de Pechpeyrou Pauline , Nicholson Patrick , Emeriau Sébastien 
Published: September 2019

Véritables vitrines et vecteurs d’image pour les marques, les sites institutionnels proposent pour la plupart une rubrique spécifique intitulée « Notre histoire ». Dans le nouveau contexte de communication digitale, les contenus que les marques y diffusent ont non seulement vocation à être traités favorablement mais aussi à être relayés par leurs lecteurs, en particulier sur les réseaux sociaux. L’une des conditions préalables à ce parcours des contenus est qu’ils suscitent de l’intérêt. Cet article mobilise de manière novatrice le concept de transport narratif pour expliquer l’intérêt porté à la lecture de l’histoire d’une marque. Les dimensions d’engagement émotionnel et de compréhension narrative ont une influence prépondérante sur l’intérêt suscité par de telles histoires et constituent donc des axes prioritaires pour orienter la communication de l’histoire des marques sur Internet.
Comment gérer les paradoxes des « ateliers putois » pour innover : le cas de l’automobile
Authors: Chen Yurong , Donada Carole 
Published: September 2019

Les « ateliers putois », plus connus sous l’anglicisme skunkworks , sont des structures organisationnelles secrètes, autonomes et parrainées par la direction générale des grandes entreprises dans le but d’innover rapidement et radicalement. Considérant les débats contradictoires sur leurs effets, cette étude interroge les conditions de réussite des skunkworks et le rôle que peut apporter le marketing dans leur succès. Deux études de cas dans l’industrie automobile ouvrent la discussion sur les caractéristiques paradoxales des skunkworks . Mises en regard avec la littérature sur le sujet, nos analyses conduisent à proposer deux pistes de recommandations managériales. L’une renvoie à l’inclusion systématique de la fonction marketing dès les premières phases de travail du skunkworks ; l’autre à la création de conditions favorables à l’intégration des bénéfices du skunkworks dans l’organisation centrale. Dans ces deux situations, le responsable marketing peut aider au rapprochement des objectifs d’innovation du skunkworks et de l’orientation marché de l’entreprise.
Les bibliothèques du Mali à l’ère du numérique
Authors: Sidibé Amadou Békaye 
Published: September 2019

Les bibliothèques, depuis quelques décennies, font face à de profonds changements qui menacent leur existence ou les obligent à se repenser totalement. Dans les pays développés, elles ont su marier numérique et pratiques bibliothéconomiques anciennes et inventer de nouveaux services. Un nouveau bibliothécaire est né et la diversification de ses services tend désormais à lui faire perdre son identité millénaire. En Afrique, particulièrement au Mali, la question des mutations dans les bibliothèques ne se pose pas dans les mêmes proportions. Certes, le pays dispose de plus en plus de bibliothécaires nouvellement formés, mais les bibliothèques sont rares, et quand elles existent, elles ne sont pas dotées d’infrastructures TIC qui permettent d’opérer des changements profonds. Dans beaucoup de bibliothèques du pays, les conditions basiques d’un bon fonctionnement (budget d’acquisition, par exemple) font défaut. Il existe aussi un déficit de coordination des bibliothèques. Dans ces conditions, les mutations perceptibles chez les autres ont du mal à se reproduire au Mali. Même s’il y a quelques services innovants dans de rares bibliothèques (bibliothèques numériques, comptes Facebook), la priorité ne serait-elle pas de faire un maillage territorial en bibliothèque, de créer les conditions pour leur bon fonctionnement et de veiller à ce qu’elles offrent les services fondamentaux aux populations ?
Neural canal ridges: A novel osteological correlate of post-cranial neurology in dinosaurs
Authors: Atterholt Jessie , Wedel Mathew J 
Published: September 2019

Bony ridges occur on the walls of the neural canal in caudal vertebrae of numerous sauropod dinosaurs. These neural canal ridges (NCRs) are anteroposteriorly elongated but do not extend to the ends of the canal. To date, we have observed NCRs in caudal vertebrae of Alamosaurus, Apatosaurus, Astrophocaudia,Brontomerus, Camarasaurus, and Diplodocus.
Numerous similar structures occur in extant vertebrates: (1) Neurocentral joints are ventral to NCRs in sauropod caudal vertebrae, and NCRs occur in unfused juvenile arches. Hypothesis rejected. (2) Attachment scars from ligamentum flavum occur at the ends of the dorsal roof of the canal, not the midpoint of the lateral edges, and this mammalian ligament was probably absent in dinosaurs. Hypothesis rejected. (3) Smooth ridges separate the spinal cord from the dorsal spinal vein and paramedullary airways in some crocodilians and birds, respectively. However, these septa persist to the ends of the canal, giving it an 8-shape, unlike the discrete NCRs of dinosaurs. Hypothesis rejected. (4) Bony attachments for denticulate ligaments occur in some non-mammalian vertebrates. The dura mater around the spinal cord fuses to the periosteum of the neural canal in non-mammals, so the denticulate ligaments that support the spinal cord can leave ossified attachment scars. These spinal cord supports have been identified in teleosts, salamanders, and a juvenile lizard, and they are the best match for the morphology of the NCRs in sauropod vertebrae.
Functions of NCRs remain obscure. Denticulate ligaments are largest in regions of the vertebral column that experience strong lateral flexion. The hypothesis that NCRs supported the spinal cord of sauropods during lateral tail-whipping is attractive, but inconsistent with our recent discovery of NCRs in a hadrosaur caudal. NCRs are a new osteological correlate of the peripheral nervous system in dinosaurs, and highlight the need for more study in this area.
Nonsteroidal Antiinflammatory Drug Use and Association With Incident Hypertension in Ankylosing Spondylitis
Authors: Liew Jean W. , Ward Michael M. , Reveille John D. , Weisman Michael , Brown Matthew A. , Lee MinJae , Rahbar Mohammed , Heckbert Susan R. , Gensler Lianne S. 
Published: September 2019

ObjectiveNonsteroidal antiinflammatory drugs (NSAIDs) increase blood pressure and potentially cardiovascular burden, which may limit their use in ankylosing spondylitis (AS). Our objective was to determine the association of NSAID use with incident hypertension in a longitudinal AS cohort.MethodsAdults with AS were enrolled in a prospective cohort study of patient outcomes and examined every 4–6 months. Hypertension was defined by patient‐reported hypertension; antihypertensive medication use; or, on 2 consecutive visits, systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg. Continuous NSAID use was dichotomized based on the validated NSAID index. We assessed the association of NSAID use as a time‐varying exposure with the incidence of hypertension using Cox proportional hazards models.ResultsOf the 1,282 patients in the cohort, 628 patients without baseline hypertension had at least 1 year of follow‐up and were included in the analysis. Of these, 72% were male, the mean age at baseline was 39 ± 13 years, and 200 patients used NSAIDs continuously. On follow‐up, 129 developed incident hypertension. After controlling for other variables, continuous NSAID use was associated with a hazard ratio of 1.12 for incident hypertension (95% confidence interval 1.04–1.20), compared to noncontinuous or no use. The association did not differ in subgroups defined by age, body mass index, biologic use, or disease activity.ConclusionIn our prospective, longitudinal AS cohort, continuous NSAID use was associated with a 12% increased risk for the development of incident hypertension, as compared to noncontinuous or no NSAID use.
Tough, Freestanding, and Colorless Photonic Paper Using Water as Ink
Authors: Xia Yongqing , Chen Binghe , Gao Shuai , Liu Yijing , Zeng Zhujun , Cao Meiwen , Wang Shengjie 
Published: September 2019

AbstractStructural colors arising from interactions of light with submicron scale periodic structures have been found in nature. Inspired by photonic materials, rewritable paper using water as ink is fabricated via entrapping amorphous colloids crystals film into hydrogel. This photonic paper is tough, free‐standing, transparent, and colorless in dry state, just like plastic sheet. Marks display using water as ink to write on the paper and disappear with the evaporation of water. The color of the marks similar to that of the initial PS colloids film and could be tuned by changing the size of the colloids. The photonic paper possesses high durability and can be rewritten over 70 cycles without significant color fading. Besides, the retention time of the written marks could be well controlled from minutes to weeks by using glycerol/water as ink. It is worth noting that long‐range order is not the necessary condition for the formation of photonic paper, which makes the preparation easy to achieve. More interesting, the wet hydrogel film is sensitive to strain, and has the potential to be mechanical sensor.
Incorporating CsF into the PbI2 Film for Stable Mixed Cation‐Halide Perovskite Solar Cells
Authors: Yi Xiaohui , Zhang Zhiming , Chang Ailing , Mao Yichen , Luan Yigang , Lin Tao , Wei Yuanzhi , Zhang Yanyan , Wang Fuyi , Cao Shaokui , Li Cheng , Wang Jizheng 
Published: September 2019

AbstractAdding a small amount of CsI into mixed cation‐halide perovskite film via a one‐step method has been demonstrated as an excellent strategy for high‐performance perovskite solar cells (PSCs). However, the one‐step method generally relies on an antisolvent washing process, which is hard to control and not suitable for fabricating large‐area devices. Here, CsF is employed and Cs is incorporated into perovskite film via a two‐step method. It is revealed that CsF can effectively diffuse into the PbI2 seed film, and drastically enhances perovskite crystallization, leading to high‐quality Cs‐doped perovskite film with a very long photoluminescence carrier lifetime (1413 ns), remarkable light stability, thermal stability, and humidity stability. The fabricated PSCs show power conversion efficiency (PCE) of over 21%, and they are highly thermally stable: in the aging test at 60 °C for 300 h, 96% of the original PCE remains. The CsF incorporation process provides a new avenue for stable high‐performance PSCs.
Working‐age people with disability and labour force participation: Geographic variations in Australia
Authors: Zhou Qingsheng , Llewellyn Gwynnyth , Stancliffe Roger , Fortune Nicola 
Published: September 2019

AbstractTo examine geographic variation in labour force participation rate (LFPR) of working‐age people with disability in Australia and associated factors. This study uses Australian Census 2016 data at Statistical Area Level 2 (SA2) and engages multiple linear regression to explore the relationship between the dependent variable,= LFPR of people with disability, and diverse independent variables that reflect collective characteristics of people with disability and their non‐disabled peers within SA2. While LFPRs for people with disability varied greatly by SA2, people with disability had considerably lower LFPR than their non‐disabled peers in all areas. The LFPRs tended to be higher in SA2s with higher percentages of people with disability who had completed year 12 or gained post‐school education, with higher household income, and where a higher proportion of people with disability mainly spoke English at home. These results indicate that where people live matters. Geographic variation in LFPR for people with disability is associated with geographic variation in their educational attainment and other social and community characteristics of the areas in which they live. This study contributes towards gaining a more sophisticated and nuanced understanding of the factors that influence LFPR of people with disability in relation to their local community environment.
Peptid‐basierte molekulare Strategien zum Einsatz bei Proteinfehlfaltung, Proteinaggregation und Zelldegeneration
Authors: Armiento Valentina , Spanopoulou Anna , Kapurniotu Aphrodite 
Published: September 2019

AbstractDie Proteinfehlfaltung in Amyloidfibrillen steht im Zusammenhang mit über 40 unheilbaren zell‐ und neurodegenerativen Krankheiten. Unter den vielen getesteten Amyloid‐inhibitorischen Molekülen fand jedoch bisher nur eines Anwendung im Patienten. In diesem Kurzaufsatz besprechen wir molekulare Strategien und peptidchemische Hilfsmittel, die bei der Entdeckung, dem Design und der Entwicklung Peptid‐basierter Leitstrukturen für Anti‐Amyloidwirkstoffe eingesetzt werden. Im Zentrum stehen zwei wichtige rationale Amyloidinhibitor‐Designstrategien: 1) Die älteste und bekannteste Strategie, die sich molekulare Erkennungselemente der Amyloidselbstassoziation zunutze macht, und 2) ein jüngerer Ansatz, der auf Kreuzamyloidwechselwirkungen beruht. Wir diskutieren, warum Peptid‐basierte Amyloidinhibitoren, insbesondere ihre fortgeschrittenen Generationen, vielversprechende Leitstrukturen oder Kandidaten für Anti‐Amyloidwirkstoffe und wertvolle Hilfsmittel bei der Aufklärung krankheitsrelevanter Zellschädigungsmechanismen werden können.
Strukturmodell von Polymermizellen in Abhängigkeit von der Curcumin‐Beladung mithilfe von Festkörper‐NMR‐Spektroskopie
Authors: Pöppler Ann‐Christin , Lübtow Michael M. , Schlauersbach Jonas , Wiest Johannes , Meinel Lorenz , Luxenhofer Robert 
Published: September 2019

AbstractDetaillierte Einblicke in die Struktur von mit Wirkstoffen beladenen Polymermizellen sind rar, aber wichtig um gezielt optimierte Transportsysteme entwickeln zu können. Wir konnten beobachten, dass eine Erhöhung der Curcumin‐Beladung von Triblockcopolymeren auf Basis von Poly(2‐oxazolinen) und Poly(2‐oxazinen) schlechtere Auflösungseigenschaften nach sich zieht. Mitthilfe von Festkörper‐NMR‐Spektroskopie und komplementären Techniken ist es möglich, ein ladungsabhängiges Strukturmodell auf molekularer Ebene zu erstellen, das eine Erklärung für die beobachteten Unterschiede liefert. Dabei belegen die Änderungen der chemischen Verschiebungen und Kreuzsignale in 2D‐NMR‐Experimenten die Beteiligung des hydrophoben Polymerblocks an der Koordination der Curcumin‐Moleküle, während bei höherer Beladung auch eine zunehmende Wechselwirkung mit dem hydrophilen Polymerblock beobachtet wird. Letztere könnte elementar für die Stabilisierung von ultrahochbeladenen Polymermizellen sowie das Design von verbesserten Wirkstofftransportsystemen sein.
Synthesis of Gb3 Glycosphingolipids with Labeled Head Groups: Distribution in Phase‐Separated Giant Unilamellar Vesicles
Authors: Sibold Jeremias , Kettelhoit Katharina , Vuong Loan , Liu Fangyuan , Werz Daniel B. , Steinem Claudia 
Published: September 2019

AbstractThe receptor lipid Gb3 is responsible for the specific internalization of Shiga toxin (STx) into cells. The head group of Gb3 defines the specificity of STx binding, and the backbone with different fatty acids is expected to influence its localization within membranes impacting membrane organization and protein internalization. To investigate this influence, a set of Gb3 glycosphingolipids labeled with a BODIPY fluorophore attached to the head group was synthesized. C24 fatty acids, saturated, unsaturated, α‐hydroxylated derivatives, and a combination thereof, were attached to the sphingosine backbone. The synthetic Gb3 glycosphingolipids were reconstituted into coexisting liquid‐ordered (lo)/liquid‐disordered (ld) giant unilamellar vesicles (GUVs), and STx binding was verified by fluorescence microscopy. Gb3 with the C24:0 fatty acid partitioned mostly in the lo phase, while the unsaturated C24:1 fatty acid distributes more into the ld phase. The α‐hydroxylation does not influence its partitioning.
Metal–Organic Frameworks Based Electrocatalysts for the Oxygen Reduction Reaction
Authors: Lu Xue Feng , Xia Bao Yu , Zang Shuang‐Quan , Lou Xiong Wen (David) 
Published: September 2019

AbstractIn view of the clean and sustainable energy, metal–organic frameworks (MOFs) based materials, including pristine MOFs, MOF composites, and their derivatives are emerging as unique electrocatalysts for oxygen reduction reaction (ORR). Thanks to their tunable compositions and diverse structures, efficient MOF‐based materials provide new opportunities to accelerate the sluggish ORR at the cathode in fuel cells and metal–air batteries. This Minireview first provides some introduction of ORR and MOFs, followed by the classification of MOF‐based electrocatalysts towards ORR. Recent breakthroughs in engineering MOF‐based ORR electrocatalysts are highlighted with an emphasis on synthesis strategy, component, morphology, structure, electrocatalytic performance, and reaction mechanism. Finally, some current challenges and future perspectives for MOF‐based ORR electrocatalysts are also discussed.
Stereoselektive C(sp3)‐C(sp2)‐Kreuzkupplungen von chiralen sekundären Alkylzinkreagenzien mit Alkenyl‐ und Arylhalogeniden
Authors: Skotnitzki Juri , Kremsmair Alexander , Keefer Daniel , Gong Ye , de Vivie‐Riedle Regina , Knochel Paul 
Published: September 2019

AbstractWir berichten über Palladium‐katalysierte Kreuzkupplungsreaktionen von chiralen sekundären nicht‐stabilisierten Dialkylzinkreagenzien – hergestellt aus einfach verfügbaren chiralen sekundären Alkyliodiden – mit Alkenyl‐ und Arylhalogeniden. Mit dieser Methode wurden α‐chirale Alkene und Arene mit sehr hoher Retention ihrer Konfiguration (dr bis zu 98:2) und guter Gesamtausbeute (bis zu 76 % über 3 Reaktionsschritte) hergestellt. Die konfigurationelle Stabilität dieser chiralen nicht‐stabilisierten Dialkylzinkreagenzien wurde bestimmt und überstieg mehrere Stunden bei 25 °C. DFT‐Berechnungen wurden durchgeführt um die Stereoretention während des katalytischen Zyklus zu erklären. Außerdem wurde die Kreuzkupplungsreaktion in der effizienten Totalsynthese der Sesquiterpene (S)‐ und (R)‐Curcumene mit Kontrolle der absoluten Stereochemie verwendet.
Mechanoluminescence or Room‐Temperature Phosphorescence: Molecular Packing‐Dependent Emission Response
Authors: Wang Jinfeng , Chai Zhaofei , Wang Jiaqiang , Wang Can , Han Mengmeng , Liao Qiuyan , Huang Arui , Lin Peixuan , Li Conggang , Li Qianqian , Li Zhen 
Published: September 2019

AbstractMechanoluminescence (ML) and room‐temperature photophosphorescence (RTP) were achieved in polymorphisms of a triphenylamine derivative with ortho‐substitution. This molecular packing‐dependent emission afforded crucial information to deeply understand the intrinsic mechanism of different emission forms and the possible packing–function relationship. With the incorporation of solid‐state 13C NMR spectra of single crystals, as well as the analysis of crystal structures, the preferred packing modes for ML and/or RTP were investigated in detail, which can guide the reasonable design of organic molecules with special light‐emission properties.
Peptide‐Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration
Authors: Armiento Valentina , Spanopoulou Anna , Kapurniotu Aphrodite 
Published: September 2019

AbstractProtein misfolding into amyloid fibrils is linked to more than 40 as yet incurable cell‐ and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and type 2 diabetes. So far, however, only one of the numerous anti‐amyloid molecules has reached patients. This Minireview gives an overview of molecular strategies and peptide chemistry “tools” to design, develop, and discover peptide‐based molecules as anti‐amyloid drug candidates. We focus on two major inhibitor rational design strategies: 1) the oldest and most common strategy, based on molecular recognition elements of amyloid self‐assembly, and 2) a more recent approach, based on cross‐amyloid interactions. We discuss why peptide‐based amyloid inhibitors, in particular their advanced generations, can be promising leads or candidates for anti‐amyloid drugs as well as valuable tools for deciphering amyloid‐mediated cell damage and its link to disease pathogenesis.
Stereoselective Csp3−Csp2 Cross‐Couplings of Chiral Secondary Alkylzinc Reagents with Alkenyl and Aryl Halides
Authors: Skotnitzki Juri , Kremsmair Alexander , Keefer Daniel , Gong Ye , de Vivie‐Riedle Regina , Knochel Paul 
Published: September 2019

AbstractWe report palladium‐catalyzed cross‐coupling reactions of chiral secondary non‐stabilized dialkylzinc reagents, prepared from readily available chiral secondary alkyl iodides, with alkenyl and aryl halides. This method provides α‐chiral alkenes and arenes with very high retention of configuration (dr up to 98:2) and satisfactory overall yields (up to 76 % for 3 reaction steps). The configurational stability of these chiral non‐stabilized dialkylzinc reagents was determined and exceeded several hours at 25 °C. DFT calculations were performed to rationalize the stereoretention during the catalytic cycle. Furthermore, the cross‐coupling reaction was applied in an efficient total synthesis of the sesquiterpenes (S)‐ and (R)‐curcumene with control of the absolute stereochemistry.
A Scalable Chemical Approach for the Synthesis of a Highly Tolerant and Efficient Oil Absorbent
Authors: Shome Arpita , Maji Kousik , Rather Adil Majeed , Yashwanth Arcot , Patel Deepak Kumar , Manna Uttam 
Published: September 2019

AbstractIn the past, bio‐inspired extreme water repellent property has been strategically embedded on commercially available sponges for developing selective oil absorbents. However, most of the reported materials lack physical and chemical durability, limiting their applicability at practically harsh settings. Herein, a stable dispersion of polymeric nanocomplexes was exploited to achieve a chemically reactive coating on the highly compressible melamine foam. A superhydrophobic melamine foam (SMF) was achieved after post‐covalent modification of the reactive coating through 1,4‐conjugate addition reaction at ambient conditions. The durability of the embedded extreme water repellent property in the as‐modified melamine foam has been elaborately demonstrated through exposing it to severe physical manipulations, chemically harsh aqueous media including pH 1, pH 12, surfactant contaminated water, river water, seawater and prolonged UV irradiation. Thus, the highly tolerant SMF was utilized as an efficient oil absorbent wherein oils of varying densities could be selectively recovered from an oil/water interface with high (e.g., 137 g g−1 for chloroform and 83 g g−1 for diesel) oil absorption capacity. Moreover, the selective oil absorption capacity of the as‐synthesized material remained unaffected at practically relevant severe chemical and physical settings, and the extreme water repellency of the material remained unaltered even after repetitive (at least 50 cycles) use for oil/water separation.
Creeping Clinical Attachment After Acellular Dermal Matrix Augmentation to Attain Root Coverage
Authors: Changi Khashayar Kordbacheh , Greenstein Gary , Tarnow Dennis , Royzman Daniel , Kang Philip 
Published: September 2019

IntroductionThis case report documents root coverage after using an acellular dermal matrix (ADM) combined with a tunneling procedure. The photographs and objective clinical measurements are presented to document a gain of new clinical attachment and subsequent creeping attachment.Case PresentationA 50‐year‐old male who demonstrated around 6 mm of recessions on the direct facial of teeth #6 through #11 had a root coverage procedure using an ADM. After 24 months, >90% of the recession defects at all sites were eliminated. It was noted that creeping clinical attachment began to appear 6 months after initial therapy on teeth #7 through# 11.ConclusionThe delayed creeping attachment seems to be due to the time necessary to vascularize the ADM and the rate of vascularization may vary with different thicknesses of inserted ADM.