bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of gaps in the asteroseismic characterization of pulsating stars
Authors: Pascual-Granado J. , Suárez J. C. , Garrido R. , Moya A. , García Hernández A. , Rodón J. R. , Lares-Martiz M. 
Published: February 2018

Context. It is known that the observed distribution of frequencies in CoRoT and Kepler δ Scuti stars has no parallelism with any theoretical model. Pre-whitening is a widespread technique in the analysis of time series with gaps from pulsating stars located in the classical instability strip, such as δ Scuti stars. However, some studies have pointed out that this technique might introduce biases in the results of the frequency analysis. Aims. This work aims at studying the biases that can result from pre-whitening in asteroseismology. The results will depend on the intrinsic range and distribution of frequencies of the stars. The periodic nature of the gaps in CoRoT observations, only in the range of the pulsational frequency content of the δ Scuti stars, is shown to be crucial to determining their oscillation frequencies, the first step in performing asteroseismology of these objects. Hence, here we focus on the impact of pre-whitening on the asteroseismic characterization of δ Scuti stars.
Methods. We select a sample of 15 δ Scuti stars observed by the CoRoT satellite, for which ultra-high-quality photometric data have been obtained by its seismic channel. In order to study the impact on the asteroseismic characterization of δ Scuti stars we perform the pre-whitening procedure on three datasets: gapped data, linearly interpolated data, and data with gaps interpolated using Autoregressive and Moving Average models (ARMA).
Results. The different results obtained show that at least in some cases pre-whitening is not an efficient procedure for the deconvolution of the spectral window. Therefore, in order to reduce the effect of the spectral window to a minimum, in addition to performing a pre-whitening of the data, it is necessary to interpolate with an algorithm that is aimed to preserve the original frequency content.
Graft-Sparing Strategy for Thoracic Prosthetic Graft Infection
Authors: Yoshida Takeshi , Kakii Bunpachi , Furui Masato , Uchino Gaku 
Published: February 2018

Objective Thoracic prosthetic graft infection is a rare but serious complication with no standard management. We reported our surgical experience on graft-sparing strategy for thoracic prosthetic graft infection.
Methods This study included patients who underwent graft-sparing surgery for thoracic prosthetic graft infection at Matsubara Tokushukai Hospital in Japan from January 2000 to October 2017.
Results There were 17 patients included in the analyses, with a mean age at surgery of 71.0 ± 10.5 years; 11 were men. In-hospital mortality was observed in five patients (29.4%).
Conclusions Graft-sparing surgery for thoracic prosthetic graft infection is an alternative option particularly for early graft infection after hemiarch replacement.
Nuss Procedure for a Patient with Negative Haller Index
Authors: Dore Mariela , Triana Junco Paloma , De La Torre Carlos , Vilanova-Sánchez Alejandra , Bret Monserrat , Gonzalez Gaspar , Nuñez Cerezo Vanesa , Jimenez Gomez Javier , Luis Encinas Jose , Hernandez Francisco , Martínez Martínez Leopoldo , Lopez Santamaria Manuel 
Published: February 2018

Introduction Minimally invasive repair for pectus excavatum (MIRPE) is controversial in extremely severe cases of pectus excavatum (PE) and an open repair is usually favored. Our aim is to describe a case of a patient with an extremely severe PE that underwent a minimally invasive approach.
Case report An 8-year-old girl with severe sternum depression was assessed. She had a history of exercise intolerance, nocturnal dyspnea, fatigue, and shortness of breath. Chest computed tomography showed that sternum depression was posterior to the anterior vertebral column; therefore, Haller and correction index could not be measured. Spirometry indicated an obstructive ventilation pattern (forced expiratory volume in 1 second = 74.4%), and echocardiogram revealed a dilated inferior vena cava, mitral valve prolapse with normal ventricular function. After multidisciplinary committee evaluation, a MIRPE approach was performed.All symptoms had disappeared at the 3-month postoperative follow-up; the desired sternum shape was achieved and normalization of cardiopulmonary function was observed. The Nuss bars were removed after a 2-year period. After 18-month follow-up, the patient can carry out normal exercise and is content with the cosmetic result.
Conclusion Nuss procedure is feasible in our 8-year-old patient. In this case, both the Haller and correction index were not useful to assess the severity of PE. Therefore, under these circumstances, other radiologic parameters have to be taken into consideration for patient evaluation.
Angiosarcoma of the Left Atrium: A Case Report
Authors: Schlachtenberger Georg , Gerfer Stephen , Kröner Axel , Wahlers Thorsten 
Published: February 2018

Background Primary cardiac tumors are rare, and many diagnosed tumors are benign with an incidence of 0.001% to 0.03%. The primary angiosarcoma is one of the malignant entities.
Discussion We discuss a case report of a 76-year-old male who underwent a preoperative diagnosis for an upcoming shoulder operation when his cardiologist diagnosed a large cardiac tumor. The patient was referred to our department where he received further diagnostics. The transesophageal echocardiography and the cardiac-magnetic resonance imaging showed a massive tumor with a dimension of 8.6 × 5.6 cm with no signs of malignity.
Method The operation was performed by standard median sternotomy. The tumor was adherent to the septum and the left atrium, and we were able to remove the specimen in toto. Pathological examinations showed an angiosarcoma with neovascularization and core expression of ERG+ and cytoplasmic expression of CD31+/CD34+, due to the size of the mass. The resection of primary cardiac tumors is mostly the therapy of choice, but in this case concerning an angiosarcoma the prognosis is poor, considering that the angiosarcoma responds very badly to chemotherapy and radiotherapy.
Which is the Best Minimal Invasive Approach for the Treatment of Spontaneous Pneumothorax? Uniport, Two, or Three Ports: A Prospective Randomized Trail
Authors: Kocaturk Celalettin , Akin Hasan , Erdogan Sertan , Bilen Salih , Karapinar Kemal , Sezen Celal , Saydam Ozkan , Kutluk Ali 
Published: February 2018

Objective Video-assisted thoracoscopic surgery (VATS) has become the standard treatment method for primary spontaneous pneumothorax. Concerns about lesser pain and better cosmesis led to the evolution of uniportal access. This study prospectively compared the results of the uniportal, two-port, and three-port thoracoscopic surgery.
Material and Methods One hundred and thirty-five patients were randomized into three groups according to the port numbers. The groups were compared regarding the operation time, hospital stay, amount of drainage, area of pleurectomy, complications, recurrences, and pain scores.
Results Except for the amount of drainage (p = 0.03), no factors were found to be statistically significant. The overall recurrence rate was 5%. Although the first and second week pain scores were not statistically significant, the single-incision group patients had significantly less pain at 4, 24, and 72 hours (p < 0.05).
Conclusion The study indicated that uniportal VATS approach is less painful and has better cosmetic results, besides it is as efficient as two- or three-port VATS approach.
TechnoCare – die Rolle assistiver Technologien in der Organisation von
Care
Authors: Kollewe Carolin 
Published: February 2018

Zusammenfassung
Technik mit Folgen Assistiven Technologien des Ambient Assisted Living (AAL – Umgebungsunterstütztes
Wohnen) wird gemeinhin in der Zukunft ein großes Potenzial in der Gestaltung von Pflege und Unterstützung
älterer und alter Menschen zugeschrieben. Sie sollen dazu beitragen, dass Menschen so lange wie möglich
selbstbestimmt und selbstständig in ihrer Wohnung bleiben können. Zu fragen ist jedoch auch, welchen Einfluss
diese Technologien auf die Pflege und Betreuung alter Menschen haben. Strukturieren solche Technologien
Arbeitsprozesse in der Pflege?
Was ist Gerontologische Pflege?
Authors: Brandenburg Hermann 
Published: February 2018

Zusammenfassung
Begriffsbestimmung Gerontologische Pflege beschreibt, analysiert und betrachtet in kritischer Weise
Pflegesituationen alter Menschen. Und das in ihrem Umfeld: im Kontext von Familie, Institutionen und der
Gesellschaft. Themenbereiche, die berührt werden, sind Klinik, Sozial- und Kulturwissenschaft, Ethik und
Politik.
Hilfreiche Technik zum Menschen bringen
Authors: Degen Lukas , Stephan René 
Published: February 2018

Zusammenfassung
Technische Alltagshilfen Das Projekt „Besser leben im Alter durch Technik“ (BLIADT) sowie weitere
Projekte und Direktbeauftragungen des FZI Forschungszentrum Informatik Karlsruhe haben sich zum Ziel gesetzt,
die Möglichkeiten technischer Assistenzsysteme der breiten Öffentlichkeit näherzubringen. Ein Dreiklang aus
persönlicher Beratung, öffentlicher Datenbank im Internet sowie bundesweiten Veranstaltungen stellt sicher,
dass Fachzielgruppen und die breite Öffentlichkeit einen umfassenden Zugang zu Informationen über
Möglichkeiten und Verfügbarkeit technischer Alltagshilfen haben.
Assessment Tinetti-Test (Performance Oriented Mobility Assessment – POMA)
Authors: Zemke Jens 
Published: February 2018

Zusammenfassung
Standarduntersuchung Der Tinetti-Test ermöglicht eine rasche und unkomplizierte Beurteilung des Gang-
und Balanceverhaltens älterer Patienten. Wie auch der Timed „Up & Go“-Test (TUG) gehört der Tinetti-Test
zu den Standarduntersuchungen im geriatrischen Mobilitätsassessment (AGAST 1995, Arbeitsgruppe Geriatrisches
Assessment) und ist Bestandteil des § 113a SGB XI Expertenstandards zur Sicherung und Weiterentwicklung der
Qualität in der Pflege.
Alt werden können im Quartier: Chancen und Herausforderungen für Menschen mit geistiger
Behinderung und für andere
Authors: Heine Michael 
Published: February 2018

Zusammenfassung
Praktizierte Teilhabe Es sind diese vier Säulen, auf denen eine erfolgreiche Quartiersentwicklung
beruht: Vernetzung und Kooperation, Information, Partizipation, Begegnung initiieren. Hier dargestellt am
Beispiel des Quartiers am Ledenhof, ein Konversionsprojekt des Landschaftsverbands Rheinland (LVR) in
Bonn-Vilich.
Mehr als vier Räder – Rollstuhlversorgung in der geriatrischen Klinik
Authors: Wittmershaus Caren 
Published: February 2018

Zusammenfassung
Individuelle Anpassung Mobilität stellt für geriatrische Patienten ein hohes Gut dar, das in der
Rollstuhlversorgung mit Respekt bedacht werden muss. Rollstuhlversorgung ist ein interdisziplinärer Prozess,
der sich an den Bedarfen des Nutzers und seines Umfelds orientiert und ein breites Wissen über Ausstattung und
Versorgungswege voraussetzt. Wenn eine gute Versorgung den Erhalt der Lebensqualität und den Schutz vor
Folgeerkrankungen gewährleisten soll, ist nur eine individuell angepasste Ausstattung zielführend.
Frakturen der Arme
Authors: Maier Klaus-Jürgen , Knobe Matthias 
Published: February 2018

Zusammenfassung
Fallbeispiele Wie proximale Oberarmfrakturen, handgelenknahe Unterarmfrakturen und periprothetische
Frakturen diagnostiziert und die Patienten am besten therapiert werden können, stellen unsere Autoren anhand
praktischer Beispiele dar.
Bedeutung des faszialen Bindegewebes bei Muskelverletzungen
Authors: Wilke Jan , Banzer Winfried 
Published: February 2018

SummaryFaszien sind keine passiven Muskelhüllen, sondern mechanisch bedeutsame Kraftüberträger innerhalb des Bewegungssystems. Mehrere Studien zeigen zudem, dass es bei Muskelverletzungen im Sport auch zu Läsionen der Faszie kommen kann. Wenngleich die klinische Relevanz dieser Schädigungen noch nicht abschließend geklärt ist, sollte in der Diagnostik und Therapie daher auch das Bindegewebe berücksichtigt werden.
Wirkeffekte differenter iterativer Ganzkörper-Hyperthermie-Verfahren auf Schmerzen und Zytokine bei rheumatischen Erkrankungen – eine aktuelle Literaturübersicht
Authors: Lange Uwe , Dischereit Gabriel 
Published: February 2018

ZusammenfassungPatienten mit rheumatischen Erkrankungen profitieren empirisch häufig sehr gut von seriellen Ganzkörper-Hyperthermie-Applikationen, ohne dass die zugrundeliegenden Wirkmechanismen im Detail bekannt sind. Trotz deutlicher Fortschritte der medikamentösen Therapieoptionen in den letzten Jahren, besteht nach den aktuellen Daten der Kerndokumentation der Arbeitsgemeinschaft Regionaler Kooperativer Rheumazentren (AGRZ) bei einem nicht unerheblichen Anteil der Patienten weiterhin eine moderate bis hohe Krankheitsaktivität mit konsekutiv mäßig bis starken Schmerzen. Dargestellt werden in diesem Artikel Studien zu differenten iterativen Ganzkörper-Hyperthermie-Applikationen und deren Einfluss auf das Schmerzempfinden sowie auf molekulare Modulatoren der Schmerzentstehung. Zusammengefasst illustrieren die objektivierten Befunde eine klinisch deutliche, mittelfristige Schmerzlinderung mit Einfluss auf hyperalgetische und analgetische Mediatoren. Erstmals bieten sich somit Erklärungen für die subjektive Schmerzlinderung.
Rainfall statistics, stationarity, and climate change
Authors: Sun Fubao , Roderick Michael L. , Farquhar Graham D. 
Published: February 2018

Significance
Precipitation shows large year-to-year variations, and there is interest in whether there have been long-lasting changes. We use a global land-based database (1940–2009) of annual precipitation and find evidence for changes at around 14% of the global land surface. In contrast, around 76% of the global land shows little or no change. Our results emphasize the importance of fully accounting for natural variability when assessing long-term precipitation change.
Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion
Authors: Lee James , Sutterlin Holly A. , Wzorek Joseph S. , Mandler Michael D. , Hagan Christine L. , Grabowicz Marcin , Tomasek David , May Mary D. , Hart Elizabeth M. , Silhavy Thomas J. , Kahne Daniel 
Published: February 2018

Significance
The outer membrane of Gram-negative bacteria, mitochondria, and chloroplasts contains proteins that adopt β-barrel structures. To maintain the integrity of this structure, the β-barrel assembly machine (Bam) folds and inserts integral membrane proteins into the outer membranes of Gram-negative bacteria. By studying the assembly of an essential β-barrel substrate we found that the two essential components of the complex, BamA and BamD, coordinate with each other upon substrate binding to facilitate folding and insertion. These results could enable the design of strategies to combat Gram-negative pathogens.
Desynchrony between brain and peripheral clocks caused by CK1δ/ε disruption in GABA neurons does not lead to adverse metabolic outcomes
Authors: van der Vinne Vincent , Swoap Steven J. , Vajtay Thomas J. , Weaver David R. 
Published: February 2018

Significance
Circadian clocks throughout the body control mammalian physiology. Disruption of circadian rhythms associated with modern 24/7 societies results in adverse metabolic consequences, but the underlying mechanisms are unknown. Internal desynchrony between the phase of central and peripheral clocks is believed to be a major contributor to these adverse consequences. Here, in the first direct test of this assumption, we show that a ∼6-h phase misalignment between circadian clocks in brain and peripheral tissues is insufficient to induce obesity and glucose intolerance in mice. These results suggest that the adverse consequences of circadian disruption may arise by multiple mechanisms, rather than arising from internal desynchrony alone.
Fast flow-based algorithm for creating density-equalizing map projections
Authors: Gastner Michael T. , Seguy Vivien , More Pratyush 
Published: February 2018

SignificanceGeographic maps are a popular means to visualize spatial statistics. Conventionally, each map region is displayed with an area proportional to the actual land area. But equal-area maps can grossly misrepresent demographic data: Densely populated cities should be given more prominence than large, but sparsely populated territories. Cartograms solve this problem by rescaling map regions in proportion to, for example, population or gross domestic products. Until now, it has generally been cumbersome or slow to calculate map projections for contiguous cartograms. Here we describe and benchmark a fast flow-based algorithm that computes cartograms in a matter of seconds, yet maintains the strengths of previous methods—a development which may lead to a more widespread adoption of cartograms.
Prospective forecasts of annual dengue hemorrhagic fever incidence in Thailand, 2010–2014
Authors: Lauer Stephen A. , Sakrejda Krzysztof , Ray Evan L. , Keegan Lindsay T. , Bi Qifang , Suangtho Paphanij , Hinjoy Soawapak , Iamsirithaworn Sopon , Suthachana Suthanun , Laosiritaworn Yongjua , Cummings Derek A.T. , Lessler Justin , Reich Nicholas G. 
Published: February 2018

SignificanceDengue hemorrhagic fever poses a major problem for public health officials in Thailand. The number and location of cases vary dramatically from year to year, which makes planning prevention and treatment activities before the dengue season difficult. We develop statistical models with biologically motivated covariates to make forecasts for each Thai province every year. The forecasts from our models have less error than those of a baseline model on out-of-sample data. Furthermore, the forecasts from a model based on incidence occurring before the start of the rainy season successfully order provinces by outbreak risk. These early, accurate forecasts of dengue hemorrhagic fever incidence could help public health officials determine where to allocate their resources in the future.
OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes
Authors: Beliveau Brian J. , Kishi Jocelyn Y. , Nir Guy , Sasaki Hiroshi M. , Saka Sinem K. , Nguyen Son C. , Wu Chao-ting , Yin Peng 
Published: February 2018

Significance
FISH enables researchers to visualize the subcellular distribution of RNA and DNA molecules in individual cells. The recent development of FISH methods employing probes composed of synthetic DNA oligonucleotides (oligos) allows researchers to tightly control aspects of probe design such as binding energy and genomic specificity. Although oligo FISH probes are central to many recently developed massively multiplexed and superresolution imaging methods, no dedicated computational utility exists to facilitate the design of such probes on the genome-wide scale. Here, we introduce a streamlined pipeline for the rapid, genome-scale design of oligo FISH probes and validate our approach by using conventional and superresolution imaging. Our method provides a framework with which to design oligo-based hybridization experiments.
Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light
Authors: Prasse Carsten , Ford Breanna , Nomura Daniel K. , Sedlak David L. 
Published: February 2018

Significance
Phenols are common anthropogenic and natural chemicals that contaminate drinking water sources. To reduce exposure to these compounds, hydroxyl radicals are often used as chemical oxidants during water treatment. Although this treatment process removes phenols, we have found that it unexpectedly produces toxic transformation products. We identify these products and simultaneously assess their toxicity with a technique that detects products formed when the transformation products react with amino acids and peptides. Our results highlight the potential risks of using oxidative treatment on alternative drinking water sources, such as contaminated groundwater and recycled municipal wastewater. They also suggest that these reactions produce these toxic transformation products in other situations, including in clouds and sunlit surface waters and within living cells.
Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Authors: Wang Yi , Jin Jing , Chung Matthew Wai Heng , Feng Ling , Sun Hongyan , Hao Quan 
Published: February 2018

Significance
Posttranslational modifications (PTMs) on histone lysines regulate gene expression and physiological functions. Succinylation is a newly discovered PTM with distinctive features. However, rarely studies have shown the function of succinylation on histone lysines. Our biochemical and structural studies demonstrate that GAS41, an oncogene-coded protein, can act as the reader of succinylation on histone H3K122. The functional significance of the pH-dependent histidine of GAS41 recognizing succinyl lysine (Ksuc) could have implications in local pH-dysregulated circumstances. The mechanism illustrated by the structures also provides an important insight into the development of specific regulators targeting the GAS41 YEATS domain in the future.
Environmental enrichment and exercise are better than social enrichment to reduce memory deficits in amyloid beta neurotoxicity
Authors: Prado Lima Mariza G. , Schimidt Helen L. , Garcia Alexandre , Daré Letícia R. , Carpes Felipe P. , Izquierdo Ivan , Mello-Carpes Pâmela B. 
Published: February 2018

SignificanceEnvironmental enrichment (EE) is a neuroprotective strategy successfully employed in the treatment of cognitive deficits in different models of brain injury or disease, including Alzheimer’s disease. However, the models used to study the effects of EE include different aspects or components that go beyond the environmental changes, as animals submitted to EE also increase physical activity levels and social interaction. Here we show that EE neuroprotection in memory deficits related to amyloid-β neurotoxicity, rather than resulting from EE per se, may rely on increased physical activity and social interaction.
The timescale of early land plant evolution
Authors: Morris Jennifer L. , Puttick Mark N. , Clark James W. , Edwards Dianne , Kenrick Paul , Pressel Silvia , Wellman Charles H. , Yang Ziheng , Schneider Harald , Donoghue Philip C. J. 
Published: February 2018

Significance
Establishing the timescale of early land plant evolution is essential to testing hypotheses on the coevolution of land plants and Earth’s System. Here, we establish a timescale for early land plant evolution that integrates over competing hypotheses on bryophyte−tracheophyte relationships. We estimate land plants to have emerged in a middle Cambrian–Early Ordovocian interval, and vascular plants to have emerged in the Late Ordovician−Silurian. This timescale implies an early establishment of terrestrial ecosystems by land plants that is in close accord with recent estimates for the origin of terrestrial animal lineages. Biogeochemical models that are constrained by the fossil record of early land plants, or attempt to explain their impact, must consider a much earlier, middle Cambrian–Early Ordovician, origin.
Variational structure of Luttinger–Ward formalism and bold diagrammatic expansion for Euclidean lattice field theory
Authors: Lin Lin , Lindsey Michael 
Published: February 2018

Significance
Many-body perturbation theory is one of the pillars of quantum many-body physics and has been used extensively to predict ground-state and excited-state electronic properties of real materials in the past few decades. Nonetheless, few practically used methods in many-body perturbation theory have been justified on a rigorous basis. We present a variational formalism that can be used for the rigorous study of a number of many-body perturbation methods in Euclidean lattice field theory. In particular, this perspective allows us to justify the widely used bold Feynman diagrammatic expansion, without relying on formal arguments such as partial resummation of Feynman diagrams to infinite order.