bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cancer Epidemiology and Cancer Care: Transforming the Landscape
Authors: Moidu Mufeeda , Sasidharan Navami , Mohandas Sreelakshmi , Krishna Sathish Kumar , Song Yao , Kannan Ravi , Sreedevi Aswathy , Gouri Balagopal Prabhakar , George Paul 
Published: December 2024

Abstract
Cancer poses the highest clinical, social, and economic burden in terms of cause-specific disability-adjusted life years. Between 30% and 50% of these cancers can currently be prevented by avoiding risk factors and implementing existing evidence-based prevention strategies. The 6th Amrita International Public Health Conference centered around the theme of “Advancing Public Health Strategies for Cancer Control.” It was a holistic approach toward discussing explicit stratagems for cancer control. The objective of this study is to document the important discussions in the trends of cancer epidemiology with a special focus on molecular epidemiology and digital technologies for screening. A model for improving the accessibility and affordability of cancer care in India is also highlighted by experts.
Reasons of Hospitalization of Subjects with Type 2 Diabetes Compared to Non-diabetes General People: Experience from a Medical College Hospital of Dhaka City
Authors: Hasan Md Rakibul , Haque Parinda Tusmee , Munira Mahbuba , Bithi Tonima Islam , Karim Rezwana , Alam Mohammad Fakhrul , Kader M. A. , Mithila Maysha Ferdous 
Published: December 2024

Context:
Diabetes is one of the most common comorbidities among hospitalized patients; however, reasons of hospitalization among diabetes patients are not well studied in Bangladesh.

Aims:
The aim of this study was to determine the reasons of hospitalization among subjects with type 2 diabetes.

Materials and Methods:
This cross-section study was done among the patients who got admitted in the general medicine ward from June 2022 to May 2024. Samples were collected by consecutive convenient sampling. Patients, who got admitted with epidemic diseases, e.g., dengue fever and COVID-19 infections, were excluded from the study. Finally, we used data of 504 patients for analysis using SPSS version 23.0.

Results:
Infection is the most common cause of hospitalization for both diabetic and nondiabetic patients, though it was a little bit higher in the nondiabetes group (52.6% vs. 65.7%; P = 0.003). Among the infectious causes, genitourinary tract infection (54.9% vs. 29.7%; P < 0.0001) and respiratory tract infection (RTI) (24.8% vs. 21.8%; P < 0.0001) are most common for both groups and significantly more common among diabetes patients. Among the noninfectious causes of hospitalization, diabetes and its complications along with other endocrine diseases was the most common (19.2%), whereas gastrointestinal disease was the most common (30.2%) cause for hospitalization in the nondiabetes group. We also observed a significantly high frequency of hypertension, renal dysfunction, cardiovascular disease, and hypothyroidism in the diabetes group.

Conclusion:
Infection is the major cause of hospitalization for both diabetes and nondiabetes subjects. Genitourinary tract and RTI are the major forms of infection during hospitalization in diabetes subjects.
Exploring Choroidal Masses: A Comprehensive Guide
Authors: Raj Pragati , Kumar Roshan , Rajan Aditya , Kant Dev 
Published: December 2024

Abstract
Choroidal osteoma is a rare benign ossifying tumor that is generally a unilateral condition in the juxtapapillary and macular area. There are multiple choroidal conditions that could remain asymptomatic and identified as an incidental finding during regular checkup, like choroidal osteoma, choroidal hemangioma, choroidal melanoma, choroidal nevus, and choroidal metastasis. We carried out a number of investigations for making a distinguished diagnosis, such as B-scan, optical coherence tomography, FFA/ICGA, and sometimes X-ray/CT-scan other than clinical examination. We hereby report a case of choroidal osteoma in a 48-year-old relatively asymptomatic female and describe an approach to differentiate similar clinical entities of the choroid.
Comparative Efficacy of Cyclosporine 0.1% and Sodium Hyaluronate 0.1% in Moderate-to-Severe Dry Eyes
Authors: Agrawal Vironika , Kumar Nishant , Shahnawaz Asif 
Published: December 2024

Abstract

Background:
Dry eye disease (DED) is accompanied by hyperosmolarity of the tear film and inflammation of the ocular surface, which in the long term is responsible for loss of goblet cells, instability of the tear film, and disturbed mucin expression.

Aim:
We aimed to compare the efficacy of sodium hyaluronate (HA) 0.1% and cyclosporine 0.1% in treating moderate-to-severe DED in terms of ocular surface disease index (OSDI) score, tear film breakup time, and Schirmer’s test.

Settings and Design:
Hospital-based, randomized clinical trial.

Materials and Methods:
The study consisted of 90 patients with moderate-to-severe dry eye condition allotted to two groups A and B to receive either cyclosporine 0.1% twice or HA 0.1% thrice for a 6-month duration. In the first 4 weeks, these drugs were given along with carboxymethyl cellulose (0.5%) four times. OSDI, Schirmer’s test, and tear breakup time (TBUT) were performed at baseline visit and at 6 weeks, 3 months, and 6 months of treatment.

Results:
In the primary analysis, the mean change from baseline in TBUT, Schirmer’s, and OSDI score was increased in both the groups (P < 0.05), although no significant intergroup differences were observed at weeks 6 and 12. However, all these tests in the 0.1% cyclosporine group showed a significant tendency for better improvement at 6 months compared with the other group (P < 0.05). No serious adverse events were observed.

Conclusion:
Both cyclosporine 0.1% and HA 0.1% are effective in treating moderate-to-severe dry eye conditions, but comparatively, cyclosporine is superior than HA in the long run.
Idiopathic CNVM in a Young Female: A Chronological Case Study of Ranibizumab Biosimilars Efficacy Using OCT Angiography
Authors: Kumar Nilesh , Singh Kanhaiya , Sharma Ashish 
Published: December 2024

Abstract
Idiopathic choroidal neovascular membranes (CNVM) represent a rare, vision-threatening condition in young individuals without identifiable predisposing factors. The pathogenesis involves disruptions in angiogenic balance, leading to abnormal blood vessel growth in the subretinal space. Diagnosis hinges on imaging techniques such as optical coherence tomography angiography (OCTA), which provides a non-invasive alternative to fluorescein angiography.
This case report highlights the successful treatment of a 21-year-old female with idiopathic CNVM using a ranibizumab biosimilar. The patient presented with sudden metamorphopsia and visual disturbances. Initial imaging confirmed CNVM with associated subretinal and intraretinal fluid. Following three intravitreal injections of the biosimilar, substantial improvement in visual acuity and lesion size was documented using OCTA. The treatment demonstrated the biosimilar's efficacy and cost-effectiveness, enhancing accessibility for long-term therapy.
The report underscores the critical role of OCTA in diagnosis and monitoring, emphasizing the utility of biosimilars in expanding therapeutic options for retinal diseases. This case validates the safety and effectiveness of biosimilars for conditions beyond their approved indications, encouraging broader adoption in clinical practice.
Factors influencing individualized nursing care in acute medical and perioperative settings: A scoping review
Authors: Ramos Ana , Sá Eunice , Pombo Delmira , Sá Florinda , Ramos Filipe , Bernardo Fernanda , Mira Helena , Lopes Hélder , Santos Paula , Marcão Regina , Gomes Idalina 
Published: December 2024

ABSTRACT
Individualized nursing care addresses the needs, experiences, behaviors, feelings, and perceptions of patients and families, but its implementation in clinical practice contexts remains challenging. This review aims to map the factors that interfere with the individualization of nursing care, in acute medical and perioperative settings. Scoping review was conducted according to the Joanna Briggs Institute guidelines. The MEDLINE, CINAHL, Cochrane, SciELO, Scientific Repository of Open Access, and LILACS databases were searched for publications from January 2017 up to March 2023. Of the 124 articles selected, 17 met the inclusion criteria. The individualization of nursing care is complex and shaped by multiple variables in the care environment, nursing, and patient characteristics. The institutional organization, the nurses’ expertise, and the patient’s attributes were identified as variables that interfere with the individualization of nursing care. Individualized nursing care is responsible for better quality of care and health outcomes. The identification of the variables that affect individualized care contributes to planning programs to improve individualization, during hospitalization and the discharge.
Understanding the concept of health literacy: A strategy to improve nursing practice
Authors: Bello Cecilia Bukola , Akinwale Oladayo Damilola , Elemile Mayowa Grace 
Published: December 2024

ABSTRACT
Health literacy (HL) is an effective approach for improved health status and measures the capacity of individuals to engage in health promotion and disease prevention activities as low HL constitutes a global problem in health-care delivery. Nurses play a significant role in providing adequate information to the client and as such it becomes imperative for them to understand the concept of HL. Clinical approach of HL refers to ability to utilize literacy skills in relation to appointments, prescriptions, and instructions for self-management. Public health approach presents HL as means of empowering individuals to take control of their health and factors that influences health. HL is a hierarchy of skills that can be assessed and managed through health education and effective communication. Nurses’ understanding of the concept of HL and strategies to reduce HL demands is crucial to delivery of effective nursing practice. This review will provide a clear understanding of the concept of HL which is essential for nurses to effectively educate patients and provide holistic care. More so, nurses will be able to assess literacy level of the patients, plan and develop better educational program tailored to patients’ level of literacy. This could invariably improve patients’ comprehension and adherence to treatment plans and overall health outcomes.
Impact of educational interventions on mothers’ awareness and communication with their attention–deficit hyperactivity disorder children
Authors: Alseraty Wafaa Hassan Hassnan , Abdullhameed Sahar Mohamed , Alenezi Atallah 
Published: December 2024

ABSTRACT

Objective:
The objectives of this study are to evaluate the effects of the educational intervention on mothers’ knowledge, awareness, and communication difficulties experienced with their children and mothers’ capacity to successfully interact with their affected child before and after the intervention.

Materials and Methods:
A quasi-experimental research design was used. A total of 30 mothers and their children complaining of attention-deficit hyperactivity disorder from four Dawadmi primary schools were included. Data were collected through a self-developed questionnaire from September 2023 to January 2024 after study acceptance by Shaqra University’s scientific deanship. Intervention prepared according to subjects’ needs and current scientific base and demonstrated in 10 sessions in schools.

Results:
Regarding mothers’ age, more than one-fourth of them (26.7%) ranged from 31 to 35 year old, and about a third (36.7%) had secondary education. Regarding mother’s job, about 76.7% do not work, and the majority of affected children (66.6%) were male, there were significant improvements in mothers’ knowledge pre- and postintervention also a significant improvement in mothers’ awareness about symptoms of poor attention, hyperactivity, and impulsivity pre- and postintervention was found. Significant differences were found before and after the intervention regarding the impact of the intervention in decreasing mothers’ challenges.

Conclusion:
The study hypothesis was accepted, and the intervention improved mothers; knowledge, awareness, and communication challenges. The intervention should be conducted and followed up for a long period of time to manage all mother’s and children’s daily challenges, improve children’s daily activities, and stabilize effective communication patterns between children and their family members.
Significance of Functional Status Scale in decannulation after pediatric tracheostomy: A single-center, retrospective study
Authors: Teplitzky Taylor B. , Randolph Nicholas Paul , Li Ji , Pereira Kevin D. , Gopalakrishnan Mathangi , Holloway Adrian 
Published: December 2024

Abstract

Background:
Metrics to successfully predict pediatric decannulation have been ineffective. The Functional Status Scale (FSS) is a validated pediatric scoring system of functional outcomes. The objective of this study was to evaluate if the FSS over time predicts pediatric tracheostomy decannulation.

Subjects and Methods:
Chart review of patients admitted to the pediatric intensive care unit (PICU) and underwent tracheostomy at a tertiary care children’s hospital from 2010 to 2019. Baseline demographics, comorbidities, tracheostomy indication, decannulation status, and FSS scores were recorded at PICU discharge and 1 and 3 years after tracheostomy. Logistic regression was performed to assess the association of FSS components with decannulation status at 3 years.

Results:
Fifty-three patients met the inclusion criteria. Forty (75.5%) patients had complete data. There were no decannulations at 1 year. Nine (22.5%) patients were decannulated at 3 years. An abnormal 3-year FSS score in the feeding domain was significantly associated with persistent tracheostomy at 3 years, with an odds ratio of 7.4 (95% confidence interval: 1.5–36.6, P = 0.01).

Conclusions:
FSS score can predict decannulation in children discharged from the PICU. This information could modify caregiver expectations and guide rehabilitative efforts.
Nutrition in neonatal and pediatric patients on extracorporeal membrane oxygenation: A survey of current practice in the US and Canada
Authors: Furlong-Dillard Jamie M. , Facciolo Michael D. , Ozment Caroline P. ,   and the Pediatric ECMO (PediECMO) Subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and Extracorporeal Life Support Organization (ELSO)
Published: December 2024

Abstract

Background:
Patients requiring extracorporeal membrane oxygenation (ECMO) are at increased risk of malnutrition due to high rates of protein catabolism, unclear metabolic needs, and safety risks with both parenteral and enteral nutrition (EN). Malnourishment is associated with increased morbidity and mortality, and improved EN and protein intake are associated with decreased 60-day mortality. A standardized practice for nutrition therapy in this population is unestablished. We aim to provide an update on current nutritional practices in pediatric and neonatal patients receiving ECMO support.

Subjects and Methods:
An online survey was distributed to ECMO medical directors in the US and Canada who had previously participated in survey-based research and those who requested participation during a pediatric ECMO presentation of this study. Each medical director was asked to forward the survey to their center’s registered dietitians (RDs).

Results:
Of 100 institutions surveyed, 36 physicians and 19 RDs responded yielding a physician response rate of 36% and an RD response rate of 19%. Physicians report “always” providing nutrition parenterally 28% and enterally 17% of the time with 11% of institutions using a protocolized approach. Nutrition therapy aids reduction of morbidity and mortality; however, there is variability in its delivery.

Conclusions:
Compared to 2015, EN is reported to be less utilized (47% vs. 55%) with less protocol use (11% vs. 38%). These data support the need for the development of a stepwise nutritional support algorithm, which is congruent with the recommendations in the Extracorporeal Life Support Organization Nutrition Guidelines.
Successful management of uncommon complication after brachiocephalic vein catheterization: A case report
Authors: Mishra Namita , Qutub Danish , Bhadani Umesh 
Published: December 2024

Abstract
Central venous catheterization is an inextricable requirement in intensive care units, long surgeries, postoperative care, and as a part of malignancy treatment that delivers intravenous fluids, drugs, inotropic agents, and intravenous feeding. Recently, different approaches for brachiocephalic vein cannulation gained interest in children and adults. We aimed to describe the rare complication of pleural effusion occurred after brachiocephalic catheterization and managed the case related to cannulation. We tried to emphasize that great vigilance is required at the time of transferring the patient to prevent the displacement and dislodgement of catheter.
An extension of the Kantorovich inequality to Hilbert spaces
Authors: Roy Saikat , Sain Debmalya 
Published: December 2024

By using the singular value decomposition, we present an extension of the famous Kantorovich inequality for a class of operators on Hilbert spaces, including the invertible ones. In particular, this extends the Kantorovich inequality for positive definite matrices due to Greub and Rheinboldt. We also obtain a refinement of the finite-dimensional version of the Kantorovich inequality for invertible operators due to Strang.
The Widths of Strict Outerconfluent Graphs
Authors: Eppstein David 
Published: December 2024

Strict outerconfluent drawing is a style of graph drawing in which vertices are drawn on the boundary of a disk, adjacencies are indicated by the existence of smooth curves through a system of tracks within the disk, and no two adjacent vertices are connected by more than one of these smooth tracks. We investigate graph width parameters on the graphs that have drawings in this style. We prove that the clique-width of these graphs is unbounded, but their twin-width is bounded.Comment: Final version for DMTCS; 17 pages, 2 figures
Business Model Canvas and Competitiveness on Financial Performance of MSMEs
Authors: Budiman Nita Andriyani , Mulyani Sri , Fithri Diana Laily , Gunawan Budi , Nugraha Fajar 
Published: December 2024

Objective: This study reveals the effect of using the Business Model Canvas (BMC) and the competitiveness on the financial performance of MSMEs.

Method: We used purposive sampling to collect data from MSMEs located in Kudus Regency, Central Java province, Indonesia. Central Java is one of the most populous provinces in Indonesia that has thousands of MSME activities. Consideration for sample selection in this study was the age of MSMEs is more than 2 years and MSMEs engaged in services, goods, and production. The number of valid samples was 410 MSMEs. Data collection was carried out by distributing questionnaires to respondents.

Result: The result shows that the Business Model Canvas and competitiveness have a significant impact on the financial performance. This research result encourages MSME owners to increase their awareness of the essence of applying strategy and increasing competitiveness in business.

Research Implications: This research suggests that the focus of government is to increase public knowledge about business models and increase the competitiveness of MSMEs.
Peningkatan Motivasi Belajar Melalui Reward Asyik Di TK Asy - Syarifiyah Garut Kelompok Usia 5 - 6 Tahun
Authors: Fadilah Resti Nurul , Kasih Delina , Suhardjo Sudi 
Published: December 2024

RESTI. Peningkatan Motivasi Belajar Melalui Reward ―ASYIK di TK Asy Syarifiyah Garut Kelompok Usia 5 – 6 Tahun (2024). Skripsi. Bekasi: Bekasi: Universitas Panca Sakti Bekasi. 2024 Untuk anak usia dini, disiplin harus dilakukan secara spontan dan menyenangkan. Orang-orang yang paling banyak mempengaruhi kedisiplinan anak adalah guru, masyarakat, dan orang tua. Mendisiplinkan anak berarti mengajarkan mereka apa yang benar dan salah. Anak-anak harus dididik tentang disiplin. Kedisiplinan adalah perilaku berorientasi nilai yang dapat dilakukan secara spontan. Penelitian yang di gunakan yaitu penelitian tindakan kelas guna pendekatan kualitatif untuk menjelaskan masalah yang ada di TK Asy-Syarifiyah Kabupaten Garut, terutama kelompok usia 5-6 tahun. Peneliti menggunakan pendekatan kualitatif dalam perilaku belajar disiplin selanjutnya. Dengan menggunakan reward ASYIK untuk membuat anak termotivasi dan senang belajar tentang perilaku disiplin belajar. Pada penelitian tindakan ini peneliti menggunakan prosedur yang disarankan oleh Kemmis dan Mc Taggart. Menurut grafik 4.5, hasil menunjukkan peningkatan pada siklus pertama sebesar 34%, siklus kedua sebesar 57%, dan siklus ketiga sebesar 79%. Alangkah baiknya jika penghargaan ASYIK ini digunakan di sekolah untuk meningkatkan proses belajar yang aktif, efektif, kreatif, dan inovatif bagi anak usia dini. Untuk menerapkan Reward ASYIK, guru dan kepala sekolah serta orang tua harus berkolaborasi untuk membuat kegiatan pembelajaran yang akan dilaksanakan. Dengan metode reward ASYIK, sekolah dapat mengajarkan orangtua tentang apa itu pembelajaran, sehingga orangtua dapat memahami maksud dan tujuan dari metode ini. Penelitian terus dilakukan untuk meningkatkan keinginan orang tua untuk disiplin belajar pada anak usia dini.
Prosedur Polya dalam Pembelajaran Kooperatif TGT untuk Meningkatkan Motivasi dan Hasil Belajar Matematika Siswa Kelas 2 SD
Authors: Sianipar Sandri , Tj Hery Winoto , Andriono Takim 
Published: December 2024

Penelitian ini bertujuan untuk meningkatkan motivasi dan hasil belajar matematika siswa kelas 2 SD di Cita Hati Christian School melalui penerapan prosedur Polya, yaitu pemahaman masalah, menemukan rencana, melaksanakan rencana dan evaluasi. Prosedur Polya ini akan diterapkan dalam pembelajaran kooperatif tipe Teams Games Tournament (TGT). Penelitian ini menggunakan metode penelitian tindakan kelas (PTK) yang dilaksanakan dalam dua siklus. Setiap siklus terdiri dari perencanaan, pelaksanaan, observasi, dan refleksi. Subjek penelitian ini adalah siswa kelas 2 yang berjumlah 22 siswa. Instrumen yang digunakan dalam penelitian ini meliputi lembar observasi dan tes hasil belajar. Hasil penelitian menunjukkan bahwa penerapan prosedur Polya dalam pembelajaran kooperatif tipe TGT dapat meningkatkan motivasi dan hasil belajar siswa di pelajaran Matematika. Hal ini dibuktikan dengan adanya konsistensi skor rata-rata motivasi belajar siswa yaitu 100% pada siklus I dan siklus II. Selain itu, hasil belajar siswa juga mengalami peningkatan, dimana rata-rata nilai tes hasil belajar siswa meningkat dari 91% pada siklus I menjadi 95% pada siklus II. Dengan demikian, dapat disimpulkan bahwa penggunaan prosedur Polya dalam pembelajaran kooperatif tipe TGT efektif dalam meningkatkan motivasi dan hasil belajar matematika siswa kelas 2 di Cita Hati Christian School.