bluuebunny/crossref_metadata_2025_split huggingface dataset:
The protective effect of resveratrol against risperidone-induced brain damage and metabolic side effects
Authors: Taştemir Korkmaz Deniz , Bilgiç Sedat , Azırak Sebile , Güvenç Ayşe Nilay , Kocaman Nevin , Özer Mehmet Kaya 
Published: September 2018

Purpose: The aim of this study was to investigate the protective effect of resveratrol (RSV) against risperidone (RIS) on weight gain/loss via of the expression of some various neurotransmitter receptors. Materials and Methods: Thirty five female Spraque-Dawley rats were divided into 5 groups (n=7): Control, RIS, RIS+RSV-1, RIS+RSV-2, RIS+RSV-3. Rats were treated orally with RIS (2 mg/kg/day) and RSV (20, 40 and 80 mg/kg/day) for 14 days. On treatment day 15, blood and brain tissues were removed for analysis. Results: The reduced neuropeptide Y1 expression levels in the RSV groups correlated with the RSV-induced weight loss. The Dopamine D1 receptor and seratonin 5-HT2c expression levels decreased significantly with RSV treatment. In addition, the RSV increased the glucose, triiodothyronine, tetraiodothyronine, and total antioxidant status, and decreased the cholesterol, triglyceride, high density lipoproteins, low density lipoproteins, thyroid-stimulating hormone, oxidative stress index, and total oxidant status levels significantly. Conclusion: The daily treatment with RSV increased the antioxidant capacity, protected the apoptotic cell injury, and the possibility of death. RSV could be an effective course of therapy to enhance therapeutic efficacy.
Tzanck yaymasının üç günden daha eski herpes lezyonlarının tanısındaki rolü
Authors: FETTAHLIOĞLU KARAMAN Bilge 
Published: September 2018

Amaç: Herpetik infeksiyonların tanısında Tzanck yayması için en uygun lezyonların 1-3 günlük olduğu bildirilmiştir. Bu çalışmada, daha uzun süreli lezyonlardan yayma yapmanın ek yarar sağlayıp sağlamayacağını değerlendirmek amaçlanmıştır.Gereç ve Yöntem: Hasta kayıtları geriye dönük olarak incelendi. Hasta dosyasında "Tzanck" sözcüğü geçen ve bu işlemin herpetik infeksiyon tanısı için yapıldığı hastalar seçildi. Lezyonların kaçıncı gününde yayma yapıldığı belirtilen hastalar çalışmaya dahil edildi. Bulgular: Yüzs eksen hastanın 65'inde bu işlem, herpetik infeksiyon tanısı için yapılmıştı. Ön tanı, hastaların 31 (%47.7)'inde herpes simpleks, 26 (%26.0)'sında herpes zoster ve 8 (%12.3)'inde varisella idi. Kesin tanı ise 16 (%34.8)'sında herpes simpleks, 26 (%56.5)'sında herpes zoster ve 4 (%8.7)'ünde varisella idi. Toplam 33 (10’u herpes simpleks, 20’si herpes zoster ve 3’ü varisella) hastada Tzanck yayma sonucu pozitif olarak kaydedilmişti. Yalnız kesin tanısı da herpetik infeksiyon olan 46 hasta ele alınacak olursa, 1-3 günlük lezyonlarda %75 (15/20), 4-6 günlük lezyonlarda %67 (10/15) ve 7-25 günlük lezyonlarda %73 (8/11) oranında pozitiflik elde edilmişti. Sonuç: Tzanck yaymasında pozitifliğin en çok veziküllerden elde edildiği, ancak püstül ve erozyon gibi öteki lezyonlardan elde edilen pozitifliğin de azımsanamayacağı, üstelik bir vezikülün üç günden uzun sürebileceği görüldü. Bu verilerin ışığında, Tzanck yaymasının daha eski lezyonlarda da yapılmasının tanıya katkı sağlayabileceği gösterilmiştir.
F-18-FDG PET/BT’de kolanjiosellüler kanseri taklit eden Fasciola hepatica vakası
Authors: KAÇMAZ Hüseyin , TUNCEL Elif Tuğba , EBİK Berat , UÇMAK Feyzullah , KAYA Muhsin , YALÇIN Kendal 
Published: September 2018

İnsan fasioliazisi, Fasciola hepatica ve Fasciola gigantica’nın neden olduğu, dünya genelinde nadir görülen zoonotik bir hastalıktır. Genellikle çiftlik hayvanlarını etkileyen bir trematod olup insan rastlantısal ara konakçıdır. Spesifik olmayan semptom ve bulgularının birçok hepatobiliyer hastalıkta izlenebilmesi nedeniyle fasioliazisin tanı ve tedavisi gecikebilmektedir. Elli üç yaşında kadın hasta 18-Florodeoksi-glukoz pozitron emisyon bilgisayaralı tomo-grafi incelemesinde ekstrahepatik safra yollarında yüksek florodeoksi-glukoz tutulumu nedeniyle kliniğimize başvurdu. Hastada son 3 aydır süren karın ağrısı, kaşıntı ve halsizlik yakınmaları mevcuttu. Kolanjiyosellüler kanseri taklit eden ve serolojik olarak tanısı konan biliyer fasioliazisli bu vakayı sunacağız.
Yaşam Tarzının Yeşil Otel Tercihinde Rolü
Authors: YILDIRIM Hacı Mehmet , SÜNNETÇİOĞLU Ayşe , ATAY Lütfi 
Published: September 2018

Tüketicilerin
davranışlarını belirleyen onlara yön veren önemli psikografik değişkenlerden
biri olan yaşam tarzı, seyahat davranışının anlaşılması ve tanımlanabilmesi
için bir araç olarak değerlendirilmektedir.
Yapılan bu çalışma tüketicilerin yaşam tarzının yeşil otel tercih etme
davranışındaki rolünü açıklamak amaçlanmaktadır. Araştırmanın örneklemi,
kolayda örnekleme yöntemi ile ulaşılan 219 akademisyenden oluşmaktadır. Araştırmada
veri toplama aracı olarak anket kullanılmıştır. Çalışmada yaşam tarzı
boyutlarını ortaya koyabilmek amacıyla açımlayıcı faktör analizi uygulanmıştır.
Tüketicilerin hangi yaşam tarzı boyutunda kümelendiğini belirlemek için kümeleme
analizi, yaşam tarzının yeşil otel tercih etme eğilimini nasıl etkilediğini
ortaya koymak için ise, basit regresyon analizi uygulanmıştır. Gerçekleştirilen
analizler sonucunda, yaşam tarzının yeşil otel tercih etme davranışındaki rolü ortaya
koyularak, yaşam tarzının yeşil otel tercih etme eğiliminin açıklayıcısı olarak
tespit edilmiştir.
Grief and Women: Stillbirth in the Social Context of India
Authors: Roberts Lisa R. , Anderson Barbara A. , Lee Jerry W. , Montgomery Susanne B. 
Published: September 2018

INTRODUCTION: Few in Western society would argue the potentially devastating impact of stillbirth related grief; but in many developing countries where stillbirth remains the highest in the world, perinatal grief is barely recognized as an issue. The purpose of this study was to explore how poor, rural central Indian women perceive and cope with stillbirths.METHODS: Seventeen key informant interviews and two focus groups (N = 33) with local health care providers, family members, and women who experienced stillbirth were conducted over a 1-month period in 2011 and then systematically coded for emerging themes using grounded theory methods to explore how women experienced stillbirth.RESULTS: Although usually never talked about and not recognized as an issue, perinatal grief emerged as a significant shared experience by all. The perceptions of stillbirth-related grief emerged in three major themes and bear evidence of gender and power issues and indicate that local social norms negatively factor heavily into their perinatal grief experiences.DISCUSSION: The findings in this richly textured study add to the limited literature regarding rural, central Indian women’s experiences with stillbirth and factors influencing their resulting perinatal grief. In light of the void of recognition of this phenomenon in Indian society, a better understanding of the context in which poor Indian women experience perinatal grief will be a first step toward developing much needed culturally rooted interventions to positively impact the women’s abilities to better cope with stillbirth in the context of their realities.
Making a Difference: The Experiences of Midwives Working With Women Who Use Illicit Drugs
Authors: Miles Maureen , Chapman Ysanne , Francis Karen 
Published: September 2018

AIM:This article describes the experiences of midwives who choose to work with pregnant women who use illicit drugs.BACKGROUND:Pregnant women who use illicit drugs present complex challenges for those who choose to work with them. Society’s views on illicit drug use fluctuate from acceptance and harm minimization to reprimand and retribution.METHOD:Qualitative interviews were conducted between June and August 2009 with 12 Australian midwives. A thematic analysis method informed by hermeneutic phenomenology was applied to interpret this data to explicate lived experiences and gain deeper understanding and meanings of this phenomenon.FINDINGS:Three major themes encapsulated the experience: making a difference, making partnerships, and learning to let go. The focus of this article, “making a difference,” included two subthemes of “working on the margins” and “transition and transformation.” The midwives were both rewarded and challenged by the needs of women who use illicit drugs and by the systems in which they worked.CONCLUSIONS:The midwives acknowledged that their aspirations “to make a difference” was not always sufficient when working with women who use illicit drugs. They also require the establishment of maternity services that are compassionate and accessible, including woman–care provider partnerships and continuity of the care environments.
A Cognitive Approach to the Treatment of Primary Inferences in Obsessive-Compulsive Disorder
Authors: O’Connor Kieron , Robillard Sophie 
Published: September 2018

In this article, it is argued that obsessive-compulsive disorder (OCD) with overt compulsions, where there is overvalued ideation, is primarily a disorder of the imagination and hence, by implication, psychological therapy should principally address the client’s imagination, rather than other cognitive processes. According to this model, the OCD client imagines a state of affairs which is then taken ‘as if it were a reality and does so because of the persuasive influence of an imaginary narrative fiction. This narrative is replayed, often in condensed form, in the OCD context and leads the client into a chain of maladaptive inferences about a possible state of affairs. The client then acts in accordance with what might be present rather than what is actually present. An inference-based approach (IBA) which directly addresses and challenges the imaginary narrative of the client is outlined, with clinical illustrations. The IBA approach complements other cognitive-behavioral therapy (CBT) and can be used in conjunction with existing CBT methods which focus more on modifying the interpretations and secondary appraisals subsequent to primary inferences.
The Impact of Depressive Illness on Spouses of Depressed Patients
Authors: Dudek Dominika , Zieba Andrzej , Jawor Miroslawa , Szymaczek Maria , Opila Janusz , Dattilio Frank M. 
Published: September 2018

This study examines the impact of major depressive illness on spouses of depressed patients. The aim of the study was to attempt to conceptualize the gender differences in the manner in which spouses experience their partnera’s disorder. Forty-eight spouses of depressed patients (22 females and 26 males) and 48 married couples with no mental health diagnosis were selected to participate in this study. The occurrence of depressive symptoms was assessed through the use of the Hamilton Depression Rating Scale (HDRS) and the Beck Depression Inventory (BDI). Thinking styles were assessed using the Rosenberg Scale (RS), Hopelessness Scale (HS), and the Automatic Thoughts Questionnaire (ATQ). Perception of the marital relationships was evaluated with the Dyadic Adjustment Scale (DAS) Results indicate more depressive symptomatology and distorted thinking patterns with the female spouses of depressed patients. The perceived quality of marital relationships by female spouses was rated to be poorer than that of male counterparts and controls. The results suggest that there exist clear differences in thinking style and perception of marital relationships between female and male spouses who are married to depressed partners.
Keeping Nursing Human
Authors: Adamski Kathy , White Linda , Dording Wendy , Schroeder Marilyn , Savett Laurence 
Published: September 2018

Stories from the experiences of four nurses at United Hospital in St. Paul, Minnesota - their collective years of service total 100 - teach many useful lessons. The power of their individual stories and those of their patients becomes evident in this two-hour conversation, which took place earlier this year. Like most good nurses, they are models for their colleagues and for those just starting their careers. Their insights are fascinating and very, very wise. We hope that they stimulate individual reflection among the readers, discussion with kindred souls and an even greater appreciation of the richness of the nursing profession. The moderator of the conversation is Laurence Savett, an internist who practiced for 28 years at United and worked with all four of these nurses. He teaches courses for aspiring health professionals at two Minnesota colleges.
Learning Situations in Nursing Education: A Concept Analysis
Authors: Shahsavari Hooman , Zare Zahra , Parsa-Yekta Zohreh , Griffiths Pauline , Vaismoradi Mojtaba 
Published: September 2018

Background and purpose:The nursing student requires opportunities to learn within authentic contexts so as to enable safe and competent practice. One strategy to facilitate such learning is the creation of learning situations. A lack of studies on the learning situation in nursing and other health care fields has resulted in insufficient knowledge of the characteristics of the learning situation, its antecedents, and consequences. Nurse educators need to have comprehensive and practical knowledge of the definition and characteristics of the learning situation so as to enable their students to achieve enhanced learning outcomes. The aim of this study was to clarify the concept of the learning situation as it relates to the education of nurses and improve understanding of its characteristics, antecedents, and consequences.Methods:The Bonis method of concept analysis, as derived from the Rodgers’ evolutionary method, provided the framework for analysis. Data collection and analysis were undertaken in two phases: “interdisciplinary” and “intra-disciplinary.” The data source was a search of the literature, encompassing nursing and allied health care professions, published from 1975 to 2016.Results:No agreement on the conceptual phenomenon was discovered in the international literature. The concept of a learning situation was used generally in two ways and thus classified into the themes of: “formal/informal learning situation” and “biologic/nonbiologic learning situation.” Antecedents to the creation of a learning situation included personal and environmental factors. The characteristics of a learning situation were described in terms of being complex, dynamic, and offering potential and effective learning opportunities. Consequences of the learning situation included enhancement of the students’ learning, professionalization, and socialization into the professional role.Implication for Practice:The nurse educator, when considering the application of the concept of a learning situation in their educational planning, must acknowledge that the application of this concept will include the student’s clinical learning experiences. More studies are required to determine factors influencing the creation of a successful learning situation from the perspectives of nurse educators and nursing students, clinical nurses and patients.
The Effects of Religious and Cultural Beliefs on Muslim Transplant Candidates During the Pretransplant Waiting Period
Authors: Sheikhalipour Zahra , Zamanzadeh Vahid , Borimnejad Leili , Valizadeh Leila , Newton Sarah , Shahbazi Mohammad , Zomorrodi Afshar , Nazari Mojtaba 
Published: September 2018

Background:Awaiting organ transplantation can be stressful, and pretransplant candidates’ religious and cultural beliefs can influence how they adapt to the stress. While little is known about the effect religious and cultural beliefs have on the pretransplant waiting period, virtually nothing is known regarding whether and how Shia Muslim patients’ religious and cultural beliefs facilitate more positive patient outcomes while they await transplantation. Therefore, it is important for nurses and other health care providers to understand transplant candidates’ experiences dealing with the stressors that present themselves during the pretransplant waiting period, especially how their religious and cultural beliefs affect their adaptation to the stressors.Aim:The purpose of this study was to explore the lived experience of Shia Muslim organ transplant candidates regarding how their religious and cultural beliefs affect their adaptation to the pretransplant waiting period.Sample:A purposeful sample of 11 Shia Muslim organ transplant candidates who were on an organ transplant waiting list in Iran (kidney,n= 4; heart,n= 4; liver,n= 3) was recruited.Method:A qualitative research design using the hermeneutical phenomenological approach was utilized in this study. In-depth unstructured interviews were conducted by one of the authors (ZS) in different locations across Iran.Results:Data analysis led to the development of six themes: “the misty road of organ transplantation,” “to accede to organ transplantation despite religious conflict,” “one step away from death,” “the master key of liberation,” “fear of the unknown,” and “reliance on God.”Nursing Implications:The findings of this study will help nurses understand the religious and cultural meaning associated with stressors experienced by Shia Muslim patients awaiting organ transplant. This information can assist nurses to develop plans of care that include patient-specific interventions that take into consideration the patients’ religious and cultural beliefs.Conclusion:Shia Muslim patients awaiting organ transplantation experience feelings that are often in conflict with their religious and cultural beliefs. However, the patients’ reliance on God during the pretransplant waiting period facilitated healthier attitudes regarding transplantation.
Becoming a Mother: Women’s Journeys From Expectation to Experience in Three European Countries
Authors: Luyben Ans G. , Kinn Sue R. , Fleming Valerie E. M. 
Published: September 2018

OBJECTIVE:To investigate important aspects of provision of routine antenatal care from women’s points of view in the Netherlands, Scotland, and Switzerland and to construct a conceptual model of care during pregnancy, informed by women.DESIGN:Grounded theory using semistructured interviews to explore women’s views. The interviews were undertaken in Dutch, English, and German.FINDINGS:In the main study, one single cross-national model emerged, which had implications for women beyond the antenatal period. “Mothering the mother” emerged as a core category. There were two subcategories: “creating a bond” and “becoming a mother.” The subcategory of “becoming a mother,” which incorporated the stages of “expecting,” “familiarizing,” and “embarking on motherhood,” is reported in this article. Women defined becoming a mother as the aim of provision of maternity care in which they described their journeys from creating expectations in early pregnancy to completing the experience approximately a year after childbirth. Mismatches between expectation and experience at the end of these journeys indicated cross-national differences in the provision of maternity care, particularly regarding the woman–care provider relationships.CONCLUSION:The findings from this study suggest that an essential aim of the maternity services was to support women in the process of becoming a mother, in the context of their own social world. Supportive conditions include woman–care provider partnerships, involvement of women’s individual social worlds in care provision, and continuity of the care providing process. These conditions should be taken into account, while designing effective models of maternity care.
General Practitioner Involvement in Remote and Rural Maternity Care: Too Big a Challenge?
Authors: Caldow Jan , Hundley Vanora , Teijlingen Edwin van , Reid John , Kiger Alice , Tucker Janet , Ireland Jilly , Harris Fiona , Farmer Jane , Bryers Helen 
Published: September 2018

BACKGROUND:In the United Kingdom, general practitioner (GP) involvement in maternity care has declined significantly over the past decade. This is particularly so in remote and rural areas where midwives have stepped up and taken over units to ensure that women in these areas continue to have a service. A recent report by the King’s Fund argues for a greater role for the GP in maternity care provision; however, this raises questions about whether GPs have the skills and training to provide such care.AIM:To explore the views of GPs on the skills and training required to deliver safe and appropriate local intrapartum services in remote and rural settings.METHODS: Mixed-method study consisting of qualitative interviews with a purposive sample of GPs in six remote and rural sites. To triangulate the interview findings and identify features that might have been missed in the interviews, a questionnaire was developed using initial key themes identified.FINDINGS:Maternity care accounted for less than 10% of most remote and rural GPs’ workload, yet interviewees reported that their role required them to be competent in a wide range of procedures. This was seen as a major barrier to recruitment and retention in rural areas. Although self-reported competence and confidence was high, several GPs felt de-skilled and felt that they were fighting a losing battle to maintain skills. GPs regarded isolation, need for comprehensive expertise, limited resources, and transportation difficulties as factors affecting the decline in their contribution to remote and rural maternity care.CONCLUSION:Although rural GPs and midwives might traditionally have been in competition, providing a woman-centered service in remote areas may be easier to achieve through collaborative working. However, if GPs are to play a greater role, then they will need to be prepared to make a strategic commitment to the maintenance of remote and rural maternity care. This will require innovative methods of training, special consideration of educational needs, and incentives for practitioners to settle in rural areas, but it may already be too late for GPs to have a substantial input into maternity care.
Competence and Competency: Core Concepts for International Midwifery Practice
Authors: Fullerton Judith T. , Ghérissi Atf , Johnson Peter G. , Thompson Joyce B. 
Published: September 2018

The global health community has implemented several initiatives over the past in the interest of accelerating country-by-country progress toward the Millennium Development Goal of improving maternal health. Skilled attendance at every birth has been recognized as an essential component of approaches for reducing maternal and perinatal morbidity and mortality.Midwives have been acknowledged as a preferred cadre of skilled birth attendant. The International Confederation of Midwives (ICM) speaks for the global community of fully qualified (professional) midwives. The ICM document entitledEssential Competencies for Basic Midwifery Practiceis a core policy statement that defines the domains and scope of practice for those individuals who meet the international definition of midwife. This article explores the meaning of competence and competency as core concepts for the midwifery profession. An understanding of the meaning of these terms can help midwives speaking individually at the clinical practice level and midwifery associations speaking at the policy level to articulate more clearly the distinction of fully qualified midwives within the skilled birth attendant and sexual and reproductive health workforce. Competence and competency are fundamental to the domains of midwifery education, legislation, and regulation, and to the deployment and retention of professional midwives.