bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pulmonary Atelectasis After Sedation With Propofol vs Propofol-Ketamine for Magnetic Resonance Imaging in Children
Authors: Bang Yu Jeong , Kim Jeayoun , Gil Nam-Su , Sim Woo Seog , Ahn Hyun Joo , Park Mi Hye , Lee Sangmin Maria , Kim Dong-Jae , Jeong Ji Seon 
Published: November 2024

ImportanceLittle is known about the impact of different anesthetic agents used for routine magnetic resonance imaging (MRI) sedation on pulmonary function in children.ObjectiveTo compare the incidence of pulmonary atelectasis after MRI sedation with propofol vs propofol-ketamine.Design, Setting, and ParticipantsThis double-masked randomized clinical trial screened 117 consecutive pediatric patients aged 3 to 12 years with American Society of Anesthesiologists physical status I to II undergoing elective MRI under deep sedation from November 2, 2022, to April 28, 2023, at a tertiary referral center. Four patients met the exclusion criteria, and 5 patients refused to participate. The participants and outcome assessors were masked to the group allocation.InterventionsDuring the MRI, the propofol group received 0.2 mL/kg of 1% propofol and 2 mL of 0.9% saline followed by a continuous infusion of propofol (200 μg/kg/min) and 0.9% saline (0.04 mL/kg/min). The propofol-ketamine group received 0.2 mL/kg of 0.5% propofol and 1 mg/kg of ketamine followed by a continuous infusion of propofol (100 μg/kg/min) and ketamine (20 μg/kg/min).Main Outcome and MeasureThe incidence of atelectasis assessed by lung ultrasonography examination.ResultsA total of 107 children (median [IQR] age, 5 [4-6] years; 62 male [57.9%]), with 54 in the propofol group and 53 in the propofol-ketamine group, were analyzed in this study. Notably, 48 (88.9%) and 31 (58.5%) patients had atelectasis in the propofol and propofol-ketamine groups, respectively (relative risk, 0.7; 95% CI, 0.5-0.8; P &amp;lt; .001). The incidence of desaturation and interruption of the MRI due to airway intervention or spontaneous movement did not significantly differ between the groups. The propofol-ketamine group showed a faster emergence time than the propofol group (15 [9-23] vs 25 [22-27] minutes in the propofol-ketamine vs propofol group; median difference in time, 9.0 minutes; 95% CI, 6.0-12.0 minutes; P &amp;lt; .001). No patient was withdrawn from the trial due to adverse effects.Conclusions and RelevanceIn this randomized clinical trial, the propofol-ketamine combination reduced sedation-induced atelectasis while allowing for faster emergence compared with propofol alone.Trial Registrationcris.nih.go.kr Identifier: KCT0007699
Because of Seeing Architecture: To Execute, It Is First Necessary To Conceive
Authors: Fiorenzoli Giuliano 
Published: November 2024

AbstractIn a world where the speed of architectural production is much accelerated, and the specificity of its representations requires a lack of ambiguity, the power and force of the hand‐drawing is still, to a few, a proving ground for testing interstitial ideas situated at the threshold of art and architecture. New York‐based Professor at the Pratt Institute School of Architecture and co‐founder of Atelier ZZiggurat, Giuliano Fiorenzoli reflects on some of his key projects, ideas and drawings – their dynamic constitutions and their symbiotic relationship with landscape/site and architecture.
The Temporalisation of Space and the Spatialisation of Time
Authors: Brown Daniel K 
Published: November 2024

AbstractThe use of machine analogies and allegories can help students liberate themselves from the tried and tested normative dogmas and doctrines propagated by architectural education. Daniel K Brown, Professor of Architecture at Victoria University of Wellington, New Zealand, and co‐guest‐editor of this AD, runs an extraordinary student design studio that has much success in conceptually intertwining machine aesthetics with history, culture and international literary narratives. Here he explains his modus operandi.
Regulating of Lithium‐Ion Dynamic Trajectory by Ferromagnetic CoF2 to Achieve Ultra‐Stable Deep Lithium Deposition Over 10000 h
Authors: Liu Ming , Ma Jiangshan , Zhang Xinyi , Wang Jie , Fan Yuqian , Song Ailing , Shao Guangjie , Ma Zhipeng 
Published: November 2024

AbstractCurrently, the realization of controllable Li electrodeposits to further extend the cycling life of Li metal anode remains challenging. Herein, it is reported that carbon nanosheet array‐loaded ferromagnetic CoF2 nanoparticles on carbon cloth (CC@CoF2/C) as an internal micro‐magnetic field source to manipulate the dynamic trajectory of Li+ deposition via the magnetohydrodynamic effect. This approach ensures uniform lithium‐ion distribution and improves deep plating capacity, achieving a prolonged cycle life of the dendrite‐free Li anode. Finite element simulations, in situ characterizations, and electrochemical tests confirm that magnetic CoF2 not only guides Li+ migration through Lorentz force to prevent dendritic growth but also improves uniform Li deposition due to the in situ conversion of LiF‐rich solid electrolyte interphase during electroplating. Meanwhile, a CC@CoF2/C‐based half‐cell operates stably over 10 000 h at 1 mA cm−2 with a low 7.8 mV overpotential. When matched with a commercial LiFePO4 cathode, the full cell reveals a high capacity of 122.96 mAh g−1 at a 2 C rate after 1000 cycles, retaining 91.95% capacity. The proposed strategy can be effectively expanded and adapted to investigate the deposition behavior of a wide range of metal anodes, offering a versatile and robust analytical framework for addressing diverse metal‐based electrochemical systems.
3D Capillary Transistors for Photothermal‐Responsive Unidirectional Liquid Transport
Authors: Liu Ruoyu , Zhou Yuning , Gao Ming , Shi Wenwan , Zhang Yuting , Liu Xiaojiang , Gu Zhongze 
Published: November 2024

AbstractUnidirectional liquid transport, a special self‐propelled wetting phenomenon observed in natural structures like the Nepenthes pitcher plant peristome, Araucaria leaves, and Crassula muscosa shoots, has inspired scientists to develop various novel microfluidic devices for liquid collection, physical/chemical reactions, and irrigation. Recently, the concept of capillary transistors is proposed to enable a programmable transport area and a significant increase in unidirectional capillary height, which is expected to greatly expand the applications of conventional microfluidic chips. In this work, using black resin as the three‐dimensional (3D) printing material, we construct microfluidic chips with capillary transistors for photothermal‐responsive unidirectional liquid transport. The transistors consist of asymmetric overhanging structures with connected overhangs, allowing for fast, long‐distance, and large‐area unidirectional liquid transport, with a unidirectional capillary height exceeding 90.0 mm—more than double the values reported in most previous studies. Furthermore, smart control of capillary height is achieved by applying external photothermal stimuli to the capillary transistors, demonstrating their potential applications in photothermal‐responsive unidirectional liquid transport and mixing in 3D space. It is envisioned that additional functions such as liquid patterning, desalination, and biochemical microreactions would be developed by engineering capillary transistors and their responsiveness.
D‐Band Center Modulation of Metallic Co‐Incorporated Co7Fe3 Alloy Heterostructure for Regulating Polysulfides in Highly Efficient Lithium‐Sulfur Batteries
Authors: Sun Lin , Xu Hongnan , Xie Jie , Yuan Yan , Wang Huaizhu , Wang Miao , Chen Xing , Jin Zhong 
Published: November 2024

AbstractLithium‐sulfur (Li‐S) batteries, with their high theoretical energy density and cost‐effectiveness, have become one of the most promising next‐generation energy storage devices. However, they still face challenges such as the “shuttle effect” caused by the dissolution of polysulfide intermediates and the slow sulfur conversion kinetics. In this study, based on the Co7Fe3 alloy catalyst, additional Co metal is introduced to form a Co7Fe3Co catalyst with a heterostructure through a simple heat treatment process. This catalyst is incorporated into Ketjenblack (KB) to form a sulfur‐infused cathode material (designated as S/KB/Co7Fe3Co). Li‐S batteries using S/KB/Co7Fe3Co as the cathode demonstrate outstanding electrochemical performance, maintaining a reversible specific capacity of over 500 mAh g−1 after 1000 cycles at a current density of 1 C, with a capacity decay rate of 0.046% per cycle. DFT theoretical calculations and experimental results both reveal that the introduction of additional Co effectively regulates the d‐band center of the material, enhancing the adsorption of polysulfide intermediates by Co7Fe3Co and promoting bidirectional catalytic sulfur conversion. This work highlights the importance of the simple construction of heterostructured catalytic materials and their role in improving the performance of Li‐S batteries.
Superior Charge Density of Triboelectric Nanogenerator via Trap Engineering
Authors: Liu Xiaoru , Zhao Zhihao , Zhang Baofeng , Hu Yuexiao , Qiao Wenyan , Gao Yikui , Wang Jing , Guo Ziting , Zhou Linglin , Wang Zhong Lin , Wang Jie 
Published: November 2024

AbstractTriboelectric nanogenerator (TENG) offers a novel approach for converting high‐entropy mechanical energy into electrical energy, yet achieving high charge density remains critical. Optimizations using dielectrics with high specific capacitance have mitigated air breakdown, but charge loss within dielectrics persists as a limiting factor. Here, based on poly(vinylidene fluoride–trifluoroethylene–chlorofluoroethylene) (P(VDF‐TrFE‐CFE)) with high specific capacitance, (P(VDF‐TrFE‐CFE)) composites’ trap density and energy are engineered using high‐polarity interfaces from barium titanate (BTO) nanoparticles and dense chain segment stacking induced by electrostatic interaction with polyetherimide (PEI) to enhance charge retention capability. With modified high interfacial traps, an ultrahigh charge density of 9.23 mC m−2 is achieved in external charge excitation (ECE) TENG using 0.2 vol% PEI/P(VDF‐TrFE‐CFE) film, marking the highest charge density reported for single‐unit TENGs. This work provides novel material strategies for high‐performance TENGs, paving the way for their large‐scale practical applications.
Modulating the Local Coordination Environment of M‐Nx Single‐Atom Site for Enhanced Electrocatalytic Oxygen Reduction
Authors: Bai Jirong , Sun Zhuangzhi , Zhang Hanyu , Lian Yuebin , Deng Yaoyao , Xiang Mei , Su Yaqiong 
Published: November 2024

AbstractEfficient, durable, and economical oxygen reduction catalysts are key for practical applications such as fuel cells and metal–air batteries. Single atom catalysts (SACs) have attracted sustained and widespread attention owing to their unique electronic properties and exceptional atomic utilization, positioning them as promising electrocatalysts in energy conversion and storage. However, the symmetric charge distribution of the metal site in the symmetric M‐N4 configuration of SACs is not conducive to electron transfer and transport in electrocatalytic reactions, resulting in a low adsorption energy for oxygen reduction reaction (ORR) related species (*OH, *O, and *OOH), which severely limits the intrinsic activity of the electrocatalysts. To overcome this limitation and improve the activity and durability, heteroatom doping can effectively modulate the local coordination environment (LCE) of the metal atom, including the coordinating atoms, coordination shells and coordination number. These modifications have significantly improved the performance of carbon supported SACs with M‐N4 configuration in the ORR. Based on this, a thorough summary of the major progress made in recent years in adjusting the LCE of SACs through doping with heteroatoms is provided and a perspective on the future development is offered here.
Boosting Hydrogen Transport in Mixed Matrix Membranes Through Continuous Spillover Via Pd‐Functionalized MOF Gel Networks
Authors: Zhang Keming , Tian Xiaohe , Xu Zhe , Huan Haishan , Zhang Rui , Feng Xiaoting , Wang Qingnan , Tang Yanting , Liu Chenlu , Wang Shaofei 
Published: November 2024

AbstractMembrane‐based gas separation offers notable energy efficiency benefits for hydrogen purification, yet it is often hindered by the inherent trade‐off between permeability and selectivity. To address this challenge, a novel mixed matrix membrane (MMM) design is presented to boost H2 separation performance via continuous hydrogen spillover mechanisms for the first time. The MMM incorporates a palladium‐functionalized ZIF‐67 gel (Pd@ZIF‐67 gel) network into a polymer of intrinsic microporosity (PIM‐1) matrix. The ZIF‐67 gel network serves as a uniform dispersion medium for palladium nanoparticles (Pd NPs), thereby generating a multitude of active sites. These exposed sites, in conjunction with the microporous structure of ZIF‐67, facilitate hydrogen dissociation and establish a continuous hydrogen spillover pathway throughout the membrane. This synergistic MMM design leads to substantial improvements in both hydrogen transport and selectivity. At an optimal loading of 28 wt% Pd@ZIF‐67 gel, the MMMs exhibit a H2 permeability of 3620 Barrer and a remarkable 417% enhancement in H2/CH4 selectivity (24.9), surpassing the 2008 upper bound. This approach paves the way for the development of advanced materials tailored for gas separation applications.
Engineering a Graphene Quantum Dot‐Enhanced Surface Plasmon Resonance Sensor for Ultra‐Sensitive Detection of Hg2⁺ Ions
Authors: Üzek Recep 
Published: November 2024

AbstractThe contamination of soil and water by heavy metals poses a significant environmental and public health concern worldwide. To address this issue, a novel graphene quantum dot (GQD)‐based surface plasmon resonance (SPR) sensor is developed for the detection of mercury ions (Hg2+), a notorious heavy metal pollutant. The thiol and amine‐functionalized GQDs (S,N‐GQDs), synthesized via pyrolysis of citric acid and L‐cysteine, are directly immobilized onto the SPR chip surface without prior pretreatment, demonstrating their potential as efficient sensing materials. The SPR sensor exhibits high sensitivity and selectivity toward Hg2+ ions, as confirmed by kinetic binding analysis and isotherm modeling. The Langmuir isotherm model, which accurately describes the interactions between Hg2+ and S,N‐GQDs, provides insights into the sensor's mechanism of action. Furthermore, the sensor demonstrates robustness and reusability, with recoveries ranging from 98% to 104% over multiple cycles of analysis. Given the presence of contaminants in tap water, the developed sensor system holds significant importance for environmental monitoring and public health protection, offering a rapid, accurate, and cost‐effective solution for detecting Hg2+ ions in such samples. Overall, this study represents a significant advancement in the field of heavy metal detection, with potential implications for addressing environmental pollution and ensuring water quality.
Enhanced Self‐Healing in Dual Network Entangled Hydrogels by Macromolecular Architecture and Alignment of Surface Functionalized hBN Nanosheets
Authors: Ratwani Chirag R. , Donato Katarzyna Z. , Grebenchuk Sergey , Mija Alice , Novoselov Kostya S. , Abdelkader Amr M. 
Published: November 2024

AbstractHydrogels have shown great promise as versatile biomaterials for various applications, ranging from tissue engineering to flexible electronics. Among their notable attributes, self‐healing capabilities stand out as a significant advantage, facilitating autonomous repair of mechanical damage and restoration of structural integrity. In this work, a dual network macromolecular biphasic composite is designed using an anisotropic structure which facilitates unidirectional chain diffusion and imparts superior self‐healing and mechanical properties. The resulting nanocomposite demonstrates significantly higher self‐healing efficiency (92%) compared to traditional polyvinyl alcohol (PVA) hydrogels, while also improving the tensile strength and elastic modulus, which typically compete with each other in soft materials. This improvement is attributed to enhanced barrier properties within the matrix due to the alignment of surface‐functionalized 2D hBN nanosheets along the biopolymer scaffold. The insights gained from this research can be leveraged to develop advanced self‐healing materials by using 2D nanofillers as “safety barriers” to define the movement of polymeric chains.
A Multi‐Volume Microfluidic Device for Automated and Wide Dynamic Range Digital LAMP Applications
Authors: Chen Kaiyue , Rong Nan , Zhang Chanqiong , Xu Jian , He Hao , Liu Wenying , Xu Yinjia , Wu Yanzhao , Ouyang Qi , Zhou Yunlong , Yu Yaojun , Yang Wei , Luo Chunxiong 
Published: November 2024

AbstractDigital nucleic acid quantification has emerged as an exceptionally valuable technique in molecular diagnosis, capturing significant attention in the biomedical field. This study introduces a novel multi‐volume digital loop‐mediated isothermal amplification (dLAMP) chip that offers an extensive detection range and user‐friendly operation. The chip consists of 1024 large chambers with the volume of 7.2 nL and 6400 small chambers with the volume of 0.064 nL. The ingenious combination of chambers with volume difference beyond a 100‐fold on the single chip enables a broad dynamic range exceeding 105 for nucleic acid quantification. Furthermore, this chip incorporates an automated strategy, enabling the rapid loading and partitioning of the reaction mixture into subvolumes within 4 min. In order to evaluate the quantitative capability of the multi‐volume dLAMP chip, a 10‐fold serial dilution of the β‐actin DNA template is measured. Additionally, the chip is tested for β‐actin DNA concentration in plasma samples from colorectal cancer patients and healthy individuals. By providing enhanced automation, wide dynamic range, and improved accuracy, this chip paves the way for broader applications and the advancement of biomedical research fields.
Impact of gastrectomy on efficacy and safety of second‐line chemotherapy patients with advanced gastric cancer: Exploratory analysis of two randomized phase III trials
Authors: Nishikawa Kazuhiro , Koizumi Wasaburo , Tsuburaya Akira , Suzuki Motoko , Morita Satoshi , Fujitani Kazumasa , Akamaru Yusuke , Shimada Ken , Hosaka Hisashi , Nishimura Ken , Yoshikawa Takaki , Tsujinaka Toshimasa , Sakamoto Junichi 
Published: November 2024

AbstractAimsSecond‐line chemotherapy (SLC) improves survival in advanced gastric cancer (AGC). Although many patients receiving SLC have undergone gastrectomy, the impact of gastrectomy on SLC remains unclear.Patients and MethodsThe objective was to evaluate the impact of gastrectomy on SLC for AGC. A total of 290 eligible patients registered in two randomized phase III trials evaluating SLC for patients with AGC was classified into the prior gastrectomy group (PGG; n = 187) or the no gastrectomy group (NGG; n = 103). We compared overall survival (OS), progression‐free survival (PFS), overall response rate (ORR), disease control rate (DCR), and safety between these two groups. Adjusted OS and adjusted PFS were estimated using inverse probability of treatment weighting (IPTW).ResultsThe PGG had better performance status (p = 0.001), more prior platinum agent (p < 0.001), and more frequent peritoneal metastasis (p = 0.006) than the NGG. The PGG had significantly better OS (13.8 vs. 9.3 mo; hazard ratio [HR]: 0.59; p < 0.001) and PFS (4.7 vs. 2.8 mo; HR: 0.58; p < 0.001) than the NGG. The PGG had significantly better adjusted OS (13.8 vs. 10.0 mo; IPTW HR: 0.66; p = 0.01) and adjusted PFS (4.3 vs. 3.2 mo; IPTW HR: 0.71; p = 0.027) than the NGG. No significant differences were observed in ORR and DCR. The incidence of Grade 3 or worse adverse events did not differ between the two groups except for a high incidence of anemia and diarrhea in the NGG.ConclusionPatients with previous gastrectomy are expected to have better survival outcomes when receiving second‐line irinotecan (IRI)‐based chemotherapy for AGC.
Numerical investigation of spindle position effects on steam ejector performance with a nonequilibrium condensation model
Authors: Ahmed Fareeha , Chen Weixiong 
Published: November 2024

AbstractThis research studied the performance of a spindle‐controlled steam ejector using models such as ideal gas and wet steam under various operating conditions based on computational fluid dynamics (CFD). A wet steam model incorporating nonequilibrium condensation was employed to simulate the complex flow phenomena within the ejector. The structure of the flow, entrainment ratio (Er), and shock wave characteristics of the steam ejector were examined in two different models. Results indicate that the spindle position has a substantial impact on steam ejector performance. For the ideal gas and wet steam models, the optimal spindle position (SP‐5) at a .1 MPa motive pressure achieves the highest entrainment ratios (Er) of 1.01 and 1.042, respectively. However, an ejector with a fixed geometry achieves Er values of only .517 and .549 for the ideal gas and wet steam models, under identical working conditions. This represents a substantial improvement of 89.8% over the fixed‐geometry ejector. The wet steam model consistently predicts 2%–4% higher Er values compared with the ideal gas model across all spindle positions. The study also reveals that increasing the motive pressure from .1 to .3 MPa reduces Er by up to 45.8% at the optimal spindle position, with the shock train length extending to 35% of the mixing chamber at .3 MPa. These findings offer insights for improving the design and optimization of variable‐geometry steam ejectors, potentially increasing efficiency in industrial applications.
Study on the characteristics of cavitation and COD removal of an addendum rotational hydrodynamic cavitation reactors
Authors: Zhou Faqi , Luo Zhiwei , Wu Xianbo , Xing Yiming , Fu Shuangcheng , Yuan Huixin 
Published: November 2024

AbstractThis paper presented an addendum rotational hydrodynamic cavitation reactors (ARHCR) that enabled circumferential shear cavitation, axial cavitation, and the Venturi effect, thus increasing cavitation efficiency. The experiments on hydroxyl (·OH) release and chemical oxygen demand (COD) removal demonstrate the feasibility of cavitation performance characterization and COD removal rate. The findings indicate that the COD removal rate can reach a maximum value of 28% or 30% with an increase in flow rate or rotating speed, respectively. Specifically, the maximum values were achieved at a rotation speed of 2,500 rpm or a flow rate of 1.0 m3·h−1. Based on the mechanism of the addendum cavitation, the wedge angles, and the crucial structural parameters, were examined for optimizing cavitation performance. The results revealed that the cavitation number and cavitation bubble were significantly influenced by wedge angles, as well as the efficiency of cavitation energy. The mechanical shear of fluid was enhanced by wedge angles, resulting in constant compression and release of fluid with increased kinetic energy. This led to stronger effects on bulge blocks, and the formation of vortexes that rebounded constantly, resulting in lower pressure areas and expanded regions of cavitation. Among the wedge angles tested, the wedge angle of 15° exhibited the highest cavitation bubbles with a maximum value of 46%. This was 31% higher than the grooves‐type cavitator reported. Furthermore, the cavitation performance was extremely improved with a wedge angle of 15°, as corresponding with the maximum efficiency of cavitation energy. These explorations provide references for the removal of COD in industrial and agricultural wastewater, as well as the development of novel reactors for wastewater treatment.