bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analytic structure of nonhydrodynamic modes in kinetic theory
Authors: Kurkela Aleksi , Wiedemann Urs Achim 
Published: September 2019

Abstract
How physical systems approach hydrodynamic behavior is governed by the decay of nonhydrodynamic modes. Here, we start from a relativistic kinetic theory that encodes relaxation mechanisms governed by different timescales thus sharing essential features of generic weakly coupled nonequilibrium systems. By analytically solving for the retarded correlation functions, we clarify how branch cuts arise generically from noncollective particle excitations, how they interface with poles arising from collective hydrodynamic excitations, and to what extent the appearance of poles remains at best an ambiguous signature for the onset of fluid dynamic behavior. We observe that processes that are slower than the hydrodynamic relaxation timescale can make a system that has already reached fluid dynamic behavior to fall out of hydrodynamics at late times. In addition, the analytical control over this model allows us to explicitly demonstrate how the hydrodynamic gradient expansion of the correlation function can be resummed such that the complete and exact non-analytic form of the correlation function can be recovered.
Sets of Pictures Avoiding Overlaps
Authors: Anselmo Marcella , Giammarresi Dora , Madonia Maria 
Published: September 2019

A string set avoids overlaps if it has the property that the prefix of each string in the set does not coincide with the suffix of any string in the set. The problem of avoiding overlaps in strings is extensively investigated since it plays an important role in the context of string matching and coding. The notion of overlap can be extended naturally to two dimensions; two pictures [Formula: see text] and [Formula: see text] have an overlap if one can put one corner of [Formula: see text] on some position in [Formula: see text] in such a way that all symbols in the common positions coincide. A picture with no self-overlaps is called unbordered and it is a generalization in two dimensions of an unbordered (or bifix-free) string.We first investigate the problem of generating all unbordered pictures of fixed size. Then, we study particular sets of unbordered pictures that are non-overlapping each others. We show that the frame of the pictures has a special role in defining these sets. In particular, we prove that there exist kinds of synchronization frames that can be put around the pictures of any set to make it non-overlapping. Finally, we present a construction of non-expandable non-overlapping sets of pictures which starts from some property of frame-completeness.
Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy
Authors: Chelko Stephen P. , Asimaki Angeliki , Lowenthal Justin , Bueno-Beti Carlos , Bedja Djahida , Scalco Arianna , Amat-Alarcon Nuria , Andersen Peter , Judge Daniel P. , Tung Leslie , Saffitz Jeffrey E. 
Published: September 2019

Background:
Inflammation is a prominent feature of arrhythmogenic cardiomyopathy (ACM), but whether it contributes to the disease phenotype is not known.

Methods:
To define the role of inflammation in the pathogenesis of ACM, we characterized nuclear factor-κB signaling in ACM models in vitro and in vivo and in cardiac myocytes from patient induced pluripotent stem cells.

Results:

Activation of nuclear factor-κB signaling, indicated by increased expression and nuclear accumulation of phospho-RelA/p65, occurred in both an in vitro model of ACM (expression of

JUP
2157del2

in neonatal rat ventricular myocytes) and a robust murine model of ACM (homozygous knock-in of mutant desmoglein-2 [
Dsg2

mut/mu
t

]) that recapitulates the cardiac manifestations seen in patients with ACM. Bay 11-7082, a small-molecule inhibitor of nuclear factor-κB signaling, prevented the development of ACM disease features in vitro (abnormal redistribution of intercalated disk proteins, myocyte apoptosis, release of inflammatory cytokines) and in vivo (myocardial necrosis and fibrosis, left ventricular contractile dysfunction, electrocardiographic abnormalities). Hearts of
Dsg2
mut/mut
mice expressed markedly increased levels of inflammatory cytokines and chemotactic molecules that were attenuated by Bay 11-7082. Salutary effects of Bay 11-7082 correlated with the extent to which production of selected cytokines had been blocked. Nuclear factor-κB signaling was also activated in cardiac myocytes derived from a patient with ACM. These cells produced and secreted abundant inflammatory cytokines under basal conditions, and this was also greatly reduced by Bay 11-7082.

Conclusions:
Inflammatory signaling is activated in ACM and drives key features of the disease. Targeting inflammatory pathways may be an effective new mechanism-based therapy for ACM.
Trade and stowaways: molecular evidence for human-mediated translocation of eastern skinks into the western Mediterranean
Authors: Bisbal-Chinesta Josep Francesc , Tamar Karin , Gálvez Ángel , Albero Luís , Vicent-Castelló Pablo , Martín-Burgos Laura , Alonso Miguel , Sánchez Rubén , Ortega Carlos , Gómez Antonio , Candel David , Cervera Miguel , Carranza Salvador , Blain Hugues-Alexandre 
Published: September 2019

Abstract
Human movements in the regions surrounding the Mediterranean Sea have caused a great impact in the composition of terrestrial fauna due to the introductions of several allochthonous species, intentionally or not. Reptiles are one of the groups where this anthropic impact is most evident, owing to the extensive intra-Mediterranean dispersals of recent chronologies. Chalcides ocellatus is a widespread skink with a natural distribution that covers almost the entire Mediterranean Basin. Two hypotheses have been proposed to explain its origin: natural dispersions and human translocations. Previous molecular data suggest the occurrence of a recent dispersal phenomenon across the Mediterranean Sea. In this study we present the first record of this species in the Iberian Peninsula, in Serra del Molar (South-east Spain). We combined molecular analyses and archaeological records to study the origin of this population. The molecular results indicate that the population is phylogenetically closely related to specimens from north-eastern Egypt and southern Red Sea. We suggest that the species arrived at the Iberian Peninsula most likely through human-mediated dispersal by using the trade routes. Between the Iron to Middle Ages, even now, the region surrounding Serra del Molar has been the destination of human groups and commercial goods of Egyptian origins, in which Chalcides ocellatus could have arrived as stowaways. The regional geomorphological evolution would have restricted its expansion out of Serra del Molar. These findings provide new data about the impact of human movements on faunal introductions and present new information relating to mechanisms of long-distance translocations.
Predicting the Atlantic Multidecadal Variability from Initialized Simulations
Authors: Si Dong , Hu Aixue , Wang Huijun , Chao Qingchen 
Published: September 2019

AbstractIn contrast to dominant interannual time-scale variability in other ocean basins, the leading observed mode variability in the Atlantic is characterized as a basinwide seesaw-like sea surface temperature variability between the North and South Atlantic on a multidecadal time scale (approximately 60–80 years), known as the Atlantic multidecadal variability (AMV). AMV has been identified as a key driver for climate shifts that occurred in the mid-1960s and late 1990s. Here we attempt to predict the summer AMV by analyzing decadal prediction experiments from two climate models. Results show that these climate models with proper initialization do a better job than uninitialized historical runs, and are capable of predicting the observed AMV time evolution. Our models predict that the AMV will be in a neutral to slightly negative phase, leading to a warm–dry trend over western Europe and North Africa and a cold–wet trend (cold relative to the warming trend) over southeastern China and Indochina in the next few years.
Climatological Changes in the Extratropical Transition of Tropical Cyclones in High-Resolution Global Simulations
Authors: Michaelis Allison C. , Lackmann Gary M. 
Published: September 2019

Abstract
Tropical cyclones (TCs) undergoing extratropical transition (ET) can develop into intense cyclonic systems accompanied by high-impact weather in areas far removed from the original TC. This study presents an analysis of multiseasonal global simulations representative of present-day and projected future climates using the Model for Prediction Across Scales–Atmosphere (MPAS-A), with high resolution (15-km grid) throughout the Northern Hemisphere. TCs are tracked as minima in sea level pressure (SLP) accompanied by a warm core, and TC tracks are extended into the extratropical phase based on local minima in SLP and use of a cyclone phase space method. The present-day simulations adequately represent observed ET characteristics such as frequency, location, and seasonal cycles throughout the Northern Hemisphere. The most significant changes in future ET events occur in the North Atlantic (NATL) basin. Here, a more favorable background environment, a shift toward stronger TC warm cores in the lower troposphere, and a significant poleward shift in TC location lead to a ~40% increase in the number of NATL ET events and a ~6% increase in the fraction of TCs undergoing ET. This equates to approximately 1–2 additional ET events per year in this region. In the future simulations, ET in the NATL occurs markedly farther north by ~4°–5°N, and the resultant extratropical cyclones are stronger by ~6 hPa. These changes hold potentially important implications for areas directly affected by ET events, such as eastern North America, as well as for regions indirectly impacted by downstream effects, including western Europe.
An Analysis of Moisture Sources of Torrential Rainfall Events over Xinjiang, China
Authors: Zhou Yu-shu , Xie Ze-ming , Liu Xin 
Published: September 2019

Abstract
Water vapor is a primary rainfall source for the development of torrential rainfall events. By using a Lagrangian flexible particle dispersion model (FLEXPART), the water vapor transports associated with torrential rainfall over Xinjiang, China, during April–September of 2008–15 are examined in this study. The results show that water vapor related to torrential rainfall events is mostly transported by westerly winds. The moisture sources for the development of torrential rainfall over four areas (Altay, Ili Valley, Hami, and Aksu-Kashgar) are mainly from Xinjiang and central Asia. The north Asia area and the Mediterranean/Black/Caspian Sea region are also important contributors to moisture source over the Altay area. Over Ili Valley, both the central Asia area and Xinjiang contribute 40% of water vapor to rainfall sources. Over the Hami area, 70% of the moisture source is from the Xinjiang. Over the Aksu-Kashgar area, the central Asia region is the most important moisture source area.
Spatial and Temporal Variations in Precipitation Amount, Frequency, Intensity, and Persistence in China, 1973–2016
Authors: Shang Hua , Xu Ming , Zhao Fen , Tijjani Sadiya Baba 
Published: September 2019

Abstract
In this paper, we examined the spatial and temporal variations in precipitation amount, frequency, and intensity in China based on daily precipitation data from 2050 weather stations from 1973 to 2016. We used two Markov chain parameters to quantify the wet persistence and dry persistence that characterizes the temporal pattern of wet and dry days, respectively. We found that China’s annual precipitation changed little from 1973 to 2016, but varied dramatically from 524 to 688 mm yr−1, with an average of 592 mm yr−1, during this period. China’s precipitation frequency, the number of days with effective precipitation (&gt;0.1 mm day−1) in a year, significantly decreased at a rate of 0.9 days decade−1 from 1973 to 2016, but precipitation intensity significantly increased at a rate of 0.12 mm day−1 decade−1 during the same period. Of the changes in China’s total precipitation amount, precipitation intensity played a dominant role, contributing 70.8%, while precipitation frequency contributed the remaining 29.2%. Little change was found in the wet persistence in China over the period of 1973–2016, but the dry persistence significantly increased with an average increasing trend of 1.62 × 10−3 probability per decade during the same period, and no significant correlations were found between these two variables. China’s precipitation also changed nonuniformly in space, with increasing trends in precipitation amount, frequency, intensity, and wet persistence in western and northeastern China but decreasing trends in the Sichuan basin, northeast of Inner Mongolia, and the Beijing–Tianjin–Hebei region.
Simultaneous Assimilation of Radar and All-Sky Satellite Infrared Radiance Observations for Convection-Allowing Ensemble Analysis and Prediction of Severe Thunderstorms
Authors: Zhang Yunji , Stensrud David J. , Zhang Fuqing 
Published: September 2019

Abstract
This study explores the benefits of assimilating infrared (IR) brightness temperature (BT) observations from geostationary satellites jointly with radial velocity (Vr) and reflectivity (Z) observations from Doppler weather radars within an ensemble Kalman filter (EnKF) data assimilation system to the convection-allowing ensemble analysis and prediction of a tornadic supercell thunderstorm event on 12 June 2017 across Wyoming and Nebraska. While radar observations sample the three-dimensional storm structures with high fidelity, BT observations provide information about clouds prior to the formation of precipitation particles when in-storm radar observations are not yet available and also provide information on the environment outside the thunderstorms. To better understand the strengths and limitations of each observation type, the satellite and Doppler radar observations are assimilated separately and jointly, and the ensemble analyses and forecasts are compared with available observations. Results show that assimilating BT observations has the potential to increase the forecast and warning lead times of severe weather events compared with radar observations and may also potentially complement the sparse surface observations in some regions as revealed by the probabilistic prediction of mesocyclone tracks initialized from EnKF analyses as various times. Additionally, the assimilation of both BT and Vr observations yields the best ensemble forecasts, providing higher confidence, improved accuracy, and longer lead times on the probabilistic prediction of midlevel mesocyclones.
DTI histogram parameters correlate with the extent of myoinvasion and tumor type in endometrial carcinoma: a preliminary analysis
Authors: Ghosh Adarsh , Singh Tulika , Singla Veenu , Bagga Rashmi , Srinivasan Radhika , Khandelwal Niranjan 
Published: September 2019

Background Myoinvasion and tumor-type determines surgical planning in endometrial carcinoma. Purpose To evaluate whole tumor diffusion tensor imaging histogram texture parameters in evaluating myoinvasion and tumor type in endometrial carcinoma. Material and Methods Twenty-seven patients with endometrial carcinoma underwent diffusion tensor imaging on a 1.5-T MRI system using echo-planar imaging sequence with 0 and 700 s/mm2 b values. Whole tumor histogram parameters were obtained from fractional anisotropy, mean diffusivity maps. Mann–Whitney U test and receiver operating characteristic curve analyses were used Results The mean fractional anisotropy of tumors with no myoinvasion was significantly higher than tumors which underwent myoinvasion, suggesting higher anisotropy in tumors which did not invade the myometrium. Voxel-wise heterogeneity in distribution of fractional anisotropy and mean diffusivity was seen in the form of higher uniformity and lower entropy of tumors with superficial <50% myoinvasion versus >50% myoinvasion. Uniformity, entropy, and energy of voxel-wise fractional anisotropy distribution gave an area under the curve of 0.827, 0.821, and 0.796, respectively, in predicting the presence of deep myometrial invasion while energy, entropy, and uniformity of mean diffusivity distribution in tumor gave an area under the curve of 0.84, 0.815, and 0.809 respectively. Tumor type was predicted with an area under the curve of 0.747, 0.759, and 0.765 for the uniformity, energy, and entropy of voxel-wise fractional anisotropy distribution. A logistic regression combining all the important histogram parameters obtained 94% and 88% sensitivity and 88% and 80% specificity in predicting deep myoinvasion and tumor type, respectively. Conclusion Diffusion tensor histogram analysis can better characterize endometrial carcinomas and can be used as a quantitative marker of tumor behavior.
Association between asymptomatic sexually transmitted infections and high-risk human papillomavirus in cervical lesions
Authors: Wang Lei , Zhu Lizhe , Li Han , Ma Nan , Huang Huifang , Zhang Xiaoling , Li Ying , Fang Jing 
Published: September 2019

Objective This study aimed to determine the association of asymptomatic sexually transmitted infections (STIs), including Ureaplasma urealyticum (UU), Mycoplasma hominis (MH), Mycoplasma genitalium, Chlamydia trachomatis, and herpes simplex virus type 2, with high-risk human papillomavirus (hrHPV) in cervical intraepithelial lesions and neoplasms. Methods A total of 320 hrHPV-positive and 160 hrHPV-negative women were divided into high-grade squamous intraepithelial lesion (HSIL) + invasive cervical cancer and low-grade squamous intraepithelial lesion + normal subgroups, respectively, on the basis of pathological cervical lesions. Cervical brush specimens were amplified and hybridized using polymerase chain reaction kits. Results MH was associated with hrHPV infection, but not with specific hrHPV genotypes or with single or multiple genotypes. Coinfection of hrHPV and UU serotype 14 (Uup14) showed an increased risk of HSILs and cervical carcinoma (odds ratio [OR]: 12.541, 95% confidence interval [CI]: 3.625–43.390). U. urealyticum biovar (Uuu) and Uup1 infections showed a similar increased risk (OR: 11.646, 95% CI: 1.493–90.850; OR: 7.474, 95% CI: 1.140–49.015, respectively) without hrHPV. Conclusions Asymptomatic STIs are widespread. This study shows an association between UU subtypes and cervical cancer, providing new insight into cervical lesion etiology. Screening for MH, Uup14, Uup1, and Uuu is important under different hrHPV statuses.
Three-Dimensional Analysis of the First Metatarsal Bone in Minimally Invasive Distal Linear Metatarsal Osteotomy for Hallux Valgus
Authors: Seki Hiroyuki , Oki Satoshi , Suda Yasunori , Takeshima Kenichiro , Kokubo Tetsuro , Nagura Takeo , Ishii Ken 
Published: September 2019

Background: Modified Bösch osteotomy (distal linear metatarsal osteotomy [DLMO]) is one of the minimally invasive correctional surgeries for hallux valgus. The 3-dimensional correctional angles and distances of the first metatarsal bone in DLMO have not been clarified. The purpose of this study was to analyze the 3-dimensional postoperative morphological changes of the first metatarsal bone in DLMO. Methods: Twenty patients (30 feet) who underwent DLMO were enrolled. Preoperative plain radiographs and computed tomography (CT) scans of the feet were examined. Postoperative radiographs and CT scans were also obtained after bone union. The surface data of the pre- and postoperative first metatarsals were reconstructed from the CT data. The positions of the distal ends of the first metatarsals described with respect to the proximal ends were calculated using CT surface-matching technique. Results: The distal end of the first metatarsal after DLMO was significantly supinated (10.2 ± 6.0 degrees, P < .001), adducted (6.0 ± 11.8 degrees, P = .004), dorsiflexed (11.1 ± 10.9, P < .001), shortened (7.4 ± 2.5 mm, P < .001), elevated (2.3 ± 3.1 mm, P = .001), and laterally shifted (8.2 ± 3.0 mm, P < .001) compared to the preoperative metatarsal distal end. Supination correction demonstrated a significant correlation with adduction correction ( r = 0.659, P < .001) on correlation analyses between these parameters. Conclusion: The 3-dimensional corrections of the first metatarsal bone after DLMO were evaluated. Pronation and abduction were successfully corrected. Furthermore, adduction correction might be an important factor affecting correction of pronation. Level of Evidence: Level IV, retrospective case series.
Review of Calcaneal Osteotomies Fixed With a Calcaneal Slide Plate
Authors: Haggerty Erin K. , Chen Stephanie , Thordarson David B. 
Published: September 2019

Background: The calcaneal slide osteotomy is a common procedure used for the surgical correction of heel varus and valgus deformities. A variety of fixation methods exist including screws and plates. The literature shows a high rate of hardware prominence with screws leading to subsequent removal of hardware. Few studies have examined the use of plates for fixation of a calcaneal osteotomy. The purpose of this study was to assess outcomes following fixation of a calcaneal osteotomy with a calcaneal slide plate. Methods: This is a retrospective consecutive case series of all patients who underwent either a medial or lateral calcaneal slide osteotomy using the specialized calcaneal slide plate between September 2013 and December 2018 by a single surgeon. The primary outcome measures were the rate of hardware removal, healing of the calcaneal osteotomy, and any associated complications such as infection or incision healing delays. Patient baseline demographics and procedure-related data were recorded. The minimum follow-up was 4 months. A total of 81 procedures were performed using this calcaneal slide plate. Results: All of the patients had one or more additional procedures at the same time as the calcaneal osteotomy. All of the calcaneal osteotomies healed without displacement. Only 1 patient (1.2%) returned to the operating room and had removal of the calcaneal slide plate, which was after osteotomy union for an infected wound. There were no cases of hardware failure or removal due to it being symptomatic. Conclusion: A specialized calcaneal slide plate was an effective fixation device for both medial and lateral calcaneal slide osteotomies for a variety of foot and ankle conditions. The union rate was 100% and none of the patients had hardware symptoms, which is an improvement on published reports of symptomatic hardware after calcaneal slide osteotomy. Level of Evidence: Level IV, retrospective case series.