bluuebunny/crossref_metadata_2025_split huggingface dataset:
Convective forces increase CXCR4-dependent glioblastoma cell invasion in GL261 murine model
Authors: Cornelison R. Chase , Brennan Caroline E. , Kingsmore Kathryn M. , Munson Jennifer M. 
Published: October 2018

AbstractGlioblastoma is the most common and malignant form of brain cancer. Its invasive nature limits treatment efficacy and promotes inevitable recurrence. Previous in vitro studies have shown that interstitial fluid flow, a factor characteristically increased in cancer, increases glioma cell invasion via CXCR4-CXCL12. It is currently unknown if these effects translate in vivo. Using the therapeutic technique of convection enhanced delivery (CED), we tested if convective flow alters glioma invasion in vivo using the syngeneic GL261 mouse model of glioblastoma. We first confirmed that GL261 invasion in vitro increased under flow in a CXCR4-CXCL12 dependent manner. Additionally, approximately 65.4% and 6.59% of GL261 express CXCR4 and CXCL12 in vivo, respectively, with 3.38% expressing both. Inducing convective flow within implanted tumors indeed increased glioma cell invasion over untreated controls, and administering CXCR4 antagonist AMD3100 (5 mg/kg) effectively eliminated this response. Therefore, glioma invasion is in fact stimulated by convective flow in vivo through CXCR4. We also analyzed patient samples to show that expression of CXCR4 and CXCL12 increase in patients following therapy. These results suggesting that targeting flow-stimulated invasion may prove beneficial as a second line of therapy, particularly in patients chosen to receive convection enhanced drug delivery.
Exploring perceptions of sustainable proteins and meat attachment
Authors: Circus Victoria Emma , Robison Rosie 
Published: October 2018

Purpose
The purpose of this paper is to explore consumer perceptions of more sustainable protein alternatives to conventional meat.

Design/methodology/approach
A mixed method design of interviews and an online survey identified key drivers and barriers to the consumption of laboratory-grown meat, edible insects and plant-based meat substitutes, with meat attachment accounted for in analyses. Differences between personal preference and perceptions of alternative proteins’ role in addressing global environmental concerns were also explored.

Findings
Findings indicated that plant-based substitutes were favoured for personal consumption for moral and ethical reasons and edible insects were least favoured due to aversion. Meat attachment was significantly associated with personal willingness to consume alternative proteins in each of the three cases. Results challenged previous research that had proposed that when considering the effectiveness of certain alternatives in addressing global environmental issues, people may advocate them but not want to consume them personally. Results imply that the congruity of these perceptions is more complex.

Research limitations/implications
Avenues for future research, including applications for exploring tailored marketing are suggested based on the preliminary findings of this study.

Originality/value
This study asked consumers to consider three alternative proteins alongside one another for the first time, exploring how meat attachment is associated with perceptions and quantifying the congruity of consumers’ personal perceptions and global perceptions of these alternative proteins.
Willingness of beef finishers to participate in supply chain collaborations
Authors: Feng Siyi , Patton Myles , Burgess Diane E. 
Published: October 2018

PurposeThe purpose of this paper is to examine the factors that influence beef farmers’ willingness to participate in supply chain collaboration initiatives and to identify attributes in formal and non-formal agreements that would encourage or discourage participation.Design/methodology/approachA face-to-face survey containing a choice experiment was carried out. Respondents were selected using stratified sampling among beef finishers in Northern Ireland. Logistic regressions were employed to examine the factors associated with willingness and agreement attributes.FindingsLarger and more specialised farms, as well as farmers with higher education attainment are shown to be more likely to participate in collaboration arrangements with downstream buyers. The choice experiment results suggest that farmers are in general willing to fulfil some feeding requirements in order to earn a premium, while a minimum price guarantee is not attractive. The positive valuation of data sharing between farms and abattoirs is found specifically among farmers with higher qualifications. Although education is shown to have positive impacts on both participation in collaboration agreements and the valuation of contract attributes, the level of education associated with the positive impacts differ. In addition, farmers who have enroled in agri-environmental schemes view the requirement of a written contract more favourably than those who have not.Originality/valueThe study adds to the understanding of how beef farmers view participation within supply chain collaborations and also how the potential features of the collaboration relate to characteristics of farmers and their farms.
New product announcement: spokesperson a manifestation of increasing firm value
Authors: Mann Bikram Jit Singh , Babbar Sonia 
Published: October 2018

PurposeBefore introducing new products, companies make announcements regarding the launch of the product which influences stock market yields of the announcing companies. Information content of the new product announcement has never been an exclusive focused stream of research. Therefore, an assessment of the impact of the content characteristics of the new product announcement on the shareholder value and the impact of source credibility (spokesperson) in making such announcements is a major gap in the existing literature. The paper aims to discuss these issues.Design/methodology/approachFirst, the standard event study methodology has been employed on the sample to measure the abnormal gains/losses accruing to the announcing firms. Second, moderated regression analysis (MRA) is employed to identify the characteristics of the new product announcement and to check the role of the spokesperson in creating shareholder value.FindingsThe results of the event study indicate that the abnormal returns are generated during the new product announcement. The results of MRA disclose the variables having a positive and a significant influence on the effective returns of the announcing companies. Likewise, the role of the spokesperson has come out brightly as a credible communicator.Originality/valueThe research provides a direction to the announcing companies regarding the content of the announcement leading to a positive perception among the investing community. Likewise, it also provides direction to the investor community about the characteristics of the announcement content they give weight age in forming a perception of strength in evaluating the new product announcement, to which they are largely unaware.
Transition in-and-out of exporting and its impact on employment growth
Authors: Lafuente Esteban , Vaillant Yancy , Moreno-Gómez Jorge 
Published: October 2018

PurposeThe purpose of this paper is to evaluate how different strategic choices related to the transitions in-and-out of exporting (export entry, export persistence, export exit) impact employment growth in Romanian small- and medium-sized businesses.Design/methodology/approachUsing linear regression models on a sample of 566 Romanian SMEs, The authors model employment growth as a function of three different dimensions of foreign market participation: export entry, persistence and exit.FindingsResults indicate that exporting is positively associated with employment growth. The findings reveal that the different strategic choices linked to exporting have a differentiating impact on employment growth: while employment growth is more pronounced among new exporters which points to the presence of an impulse effect of exporting, businesses that interrupt their exporting activities report employment losses.Research limitations/implicationsThis study underlines the relevance of distinguishing the specific impact of the different export behaviours related to the transitions in-and-out of exporting.Practical implicationsThe results of the study fuel the debate on the relevance of promoting policies that encourage exporting among small businesses operating in emerging economies.Originality/valueThis study presents an original analysis of the distinctive effect that different forms of export behaviour related to the transitions in-and-out of exporting have on employment growth. The relevance of this study not only flows from the particular empirical design that simultaneously evaluates different export choices and their specific impact on employment growth.
Futures market efficiency and effectiveness of hedge in Indian currency market
Authors: Kharbanda Varuna , Singh Archana 
Published: October 2018

PurposeCorporate treasurers manage the currency risk of their organization by hedging through futures contracts. The purpose of this paper is to evaluate the effectiveness of hedging by US currency futures contracts by taking into account the efficiency of the currency market.Design/methodology/approachThe static models for calculating hedge ratio are as popular as dynamic models. But the main disadvantage with the static models is that they do not consider important properties of time series like autocorrelation and heteroskedasticity of the residuals and also ignore the cointegration of the market variables which indicate short-run market disequilibrium. The present study, therefore, measures the hedging effectiveness in the US currency futures market using two dynamic models – constant conditional correlation multivariate generalized ARCH (CCC-MGARCH) and dynamic conditional correlation multivariate GARCH (DCC-MGARCH).FindingsThe study finds that both the dynamic models used in the study provide similar results. The relative comparison of CCC-MGARCH and DCC-MGARCH models shows that CCC-MGARCH provides better hedging effectiveness result, and thus, should be preferred over the other model.Practical implicationsThe findings of the study are important for the company treasurers since the new updated Indian accounting standards (Ind-AS), applicable from the financial year 2016–2017, make it mandatory for the companies to evaluate the effectiveness of hedges. These standards do not specify a quantitative method of evaluation but provide the flexibility to the companies in choosing an appropriate method which justifies their risk management objective. These results are also useful for the policy makers as they can specify and list the appropriate methods for evaluating the hedge effectiveness in the currency market.Originality/valueMajorly, the studies on Indian financial market limit themselves to either examining the efficiency of that market or to evaluate the effectiveness of the hedges undertaken. Moreover, most of such works focus on the stock market or the commodity market in India. This is one of the first studies which bring together the concepts of efficiency of the market and effectiveness of the hedges in the Indian currency futures market.
Macroeconomic determinants of stock market development in South Africa
Authors: Ho Sin-Yu 
Published: October 2018

PurposeThe purpose of this paper is to examine the macroeconomic determinants of stock market development in South Africa during the period 1975–2015. Specifically, it examines the impact of banking sector development, economic growth, inflation rate, real interest rate and trade openness on the development of the South African stock market.Design/methodology/approachThe author employs autoregressive distributed lag bounds testing procedure that allows the author to empirically investigate both the short- and long-run relationships between the stock market development and its determinants in the context of South Africa. In addition, the author also conducts a sensitivity analysis by accounting for the presence of structural breaks in the underlying series to check for the robustness of the estimation.FindingsThis paper confirms the findings by other studies that banking sector development and economic growth promote stock market development, while inflation rate and real interest rate inhibit stock market development. In addition, this paper finds an interesting result in the fact that trade openness has a negative impact on stock market development, which is different from the findings of many other studies.Originality/valueCurrently, while the theoretical and empirical literature presents diverse views on the relationship between each determinant and stock market development, no study has focussed on the South African stock market. Given the significant role that the South African stock market plays in Africa as measured by its market capitalisation and market capitalisation ratio, there is a need for a better understanding of the macroeconomic factors influencing its development.
Terrorism in OPEC countries and oil prices
Authors: Bassil Charbel , Hamadi Hassan , Bteich Marion 
Published: October 2018

Purpose
The purpose of this paper is to examine the impact of terrorism in the Organization of the Petroleum Exporting Countries (OPEC) on the return and volatility of world price of oil.

Design/methodology/approach
GARCH models and daily data from 1987 till 2015 will be used.

Findings
The empirical results reveal that terrorism in the OPEC affects positively oil returns and negatively its volatility. Results also show that the different characteristics of the attacks are likely to have different impact on the return and volatility of oil prices. In overall terms, terrorism has a much larger positive impact on the return of oil prices and negative impact on its volatility if it targets the oil industry in the OPEC. This marginal effect is even greater if those attacks were successful.

Originality/value
The distinguishing feature of this paper is that the authors use a framework that takes into account different attributes for terrorism the success of the attacks, the intensity of the attacks and the associated targets.
Yours ethically
Authors: Potdar Balkrushna , Guthrie John , Gnoth Juergen , Garry Tony 
Published: October 2018

Purpose
Corporate social responsibility (CSR) is increasingly considered a central tenant of marketing strategy and a source of competitive advantage within the retail sector. As such, it may affect a supermarket’s customer, employee, and other stakeholder attitudes and behaviours. This research explores how a supermarket’s involvement in CSR activities may influence employee engagement and how this may manifest itself in positive employee behaviours. Specifically, the purpose of this paper is to empirically examine the role of CSR and its impact on employee engagement and consequently, employee propensity to exhibit intervention behaviours to prevent in-store retail crime.

Design/methodology/approach
This research uses a phenomenological approach through semi-structured in-depth interviews with shop-floor employees of a national supermarket chain.

Findings
Findings suggest that external and internal CSR practices of supermarkets are important in shaping organisational engagement behaviours among employees. Additionally, heightened employee engagement may have a significant impact on employee propensity to engage in shoplifting prevention behaviours. A conceptual model is developed based on these findings.

Practical implications
Retail managers should fully communicate CSR practices to employees to increase employee engagement and consequential shoplifting intervention prevention behaviours.

Originality/value
The contribution of this paper is twofold. First and from a theoretical perspective, it offers both a conceptual foundation and empirical-based evaluation of CSR and its impact on employee engagement and specifically, shoplifting prevention behaviours. Second and from a pragmatic perspective, the conceptual model derived from this research may aid retailers in developing and communicating CSR strategies that engage employees and consequently lead to shoplifting prevention behaviours.
Green leasing in commercial real estate
Authors: Collins Dave , Junghans Antje , Haugen Tore 
Published: October 2018

PurposeThis paper aims to investigate the drivers and barriers for green leases and tenancies in sustainable “Building Research Establishment Environmental Assessment Method” (BREEAM) and “Leadership in Energy and Environmental Design” (LEED) certified office and office buildings in Norway, the UK and the USA. This study focuses on the differing perspectives between owners and tenants. It is then considered as to how these issues are dealt with during different phases of a buildings life cycle. This research is based on existing literature and semi-structured interviews that studied qualitative and quantitative elements in the context of ownership and tenancy of single and multi-tenanted sustainable office buildings.Design/methodology/approachUsing a mixed-method approach involving semi-structured interviews with both qualitative and quantitative elements along with desk research, this paper evaluates how green leases and tenancies in offices and office buildings that are BREEAM and LEED certified require a reconsideration and re-evaluation of the acquisition, operation and disposal of office buildings by building owners and their tenants. These stakeholder relationships are supported theoretically using a theoretical model that outlines the interrelation between the sustainable building and the relationships of the building owner, the user and the FM service provider.FindingsThe data gathered from the interviews justify and partly contradict some of the statements within existing literature, diminishing the importance of cost and the barrier of split incentive but instead illuminate the importance of less tangible considerations such as company policy or a sustainability strategy. The results also note the realisation of a changing market for commercial real estate driven by the sustainable business needs of tenants for the occupation of workspaces.Research limitations/implicationsThese findings have the potential to further develop theories and provide an insight into how the relationships between actors from a business, procurement and contractual perspective need to be developed to ensure more proactive development of green leasing of new and existing sustainable office buildings, along with where strategic attention is required during the building design, construction, operational and use phases.Originality/valueThis paper is based on original research through interviews and literature studies supported by an existing theoretical model. The results have been partly presented and initially discussed at the WBC World Congress 2016 in Tampere, Finland.
I’ll have the usual: how restaurant brand image, loyalty, and satisfaction keep customers coming back
Authors: Espinosa Jennifer A. , Ortinau David J. , Krey Nina , Monahan Lisa 
Published: October 2018

Purpose
The purpose of this paper is to study how repeat customers utilize their established overall restaurant brand image (ORBI), overall restaurant loyalty, satisfaction and behavioral intentions (revisit, recommend) to reengage with a casual-dining restaurant brand.

Design/methodology/approach
The study design consists of a mixed-methods, two-phase research approach that includes both qualitative and quantitative data. First, focus groups and in-depth interviews with adult customers reveal preliminary insights on restaurant dining patterns and familiarity with franchised casual dining restaurants. Second, an online self-administered survey tests the influence of ORBI on repeat customers’ overall restaurant loyalty, satisfaction and behavioral intentions.

Findings
For repeat customers, ORBI positively predicts loyalty and satisfaction. Loyalty and satisfaction mediate the relationship between ORBI and intentions to recommend, while loyalty alone mediates the relationship between ORBI and intentions to revisit a casual dining restaurant.

Practical implications
Managers looking to stimulate recommendation intentions can increase ORBI, loyalty or satisfaction among repeat customers; or choose some combination of these three predictors. To improve revisit intentions, managers should first increase loyalty, followed by ORBI. Importantly, management needs to tailor information given to repeat customers differently than other customers.

Originality/value
This paper provides a first conceptualization of how both loyalty and satisfaction jointly mediate the relationships between ORBI and two behavioral intentions (revisit, recommend). The results show that loyalty plays a significant role in these predictive relationships and is more important than satisfaction for enhancing intentions to revisit a restaurant.
A processing diagram for high-density Ti-6Al-4V by selective laser melting
Authors: Wang Yinmin (Morris) , Kamath Chandrika , Voisin Thomas , Li Zan 
Published: October 2018

Purpose
Density optimization is the first critical step in building additively manufactured parts with high-quality and good mechanical properties. The authors developed an approach that combines simulations and experiments to identify processing parameters for high-density Ti-6Al-4V using the laser powder-bed-fusion technique. A processing diagram based on the normalized energy density concept is constructed, illustrating an optimized processing window for high- or low-density samples. Excellent mechanical properties are obtained for Ti-6Al-4V samples built from the optimized window.

Design/methodology/approach
The authors use simple, but approximate, simulations and selective experiments to design parameters for a limited set of single track experiments. The resulting melt-pool characteristics are then used to identify processing parameters for high-density pillars. A processing diagram is built and excellent mechanical properties are achieved in samples built from this window.

Findings
The authors find that the laser linear input energy has a much stronger effect on the melt-pool depth than the melt-pool width. A processing diagram based on normalized energy density and normalized hatch spacing was constructed, qualitatively indicating that high-density samples are produced in a region when 1 < E* < 2. The onset of void formation and low-density samples occur as E* moves beyond a value of 2. The as-built SLM Ti-6Al-4V shows excellent mechanical performance.

Originality/value
A combined approach of computer simulations and selected experiments is applied to optimize the density of Ti-6Al-4V, via laser powder-bed-fusion (L-PBF) technique. A series of high-density samples are achieved. Some special issues are identified for L-PBF processes of Ti-6Al-4V, including the powder particle sticking and part swelling issues. A processing diagram is constructed for Ti-6Al-4V, based on the normalized energy density and normalized hatch spacing concept. The diagram illustrates windows with high- and low-density samples. Good mechanical properties are achieved during tensile tests of near fully dense Ti-6Al-4V samples. These good properties are attributed to the success of density optimization processes.