bluuebunny/crossref_metadata_2025_split huggingface dataset:
Group-IV pentaoctite: a new 2D material family
Authors: Kegler Vanessa D , de Oliveira Igor S S , Pacine Dominike , Nunes Ricardo W , Pereira Teldo A S , Lima Erika N 
Published: November 2024

Abstract
This study investigates the structural, mechanical, and electronic properties of novel two-dimensional (2D) pentaoctite (PO) monolayers composed of group-IV elements (PO-C, PO-Si, PO-Ge, and PO-Sn) using first-principles calculations. Stability is explored through phonon spectra and ab initio molecular dynamics simulations, confirming that all proposed structures are dynamically and thermally stable. Mechanical analysis shows that the PO-C monolayer exhibits exceptional rigidity, while the others demonstrate greater flexibility, making them suitable for applications in foldable materials. The electronic properties show semimetallic behavior for PO-C, while PO-Si, PO-Ge, and PO-Sn possess narrow band gaps, positioning them as promising candidates for semiconductor applications. Additionally, PO-C, PO-Si, and PO-Ge exhibit potential as an efficient catalyst for the hydrogen evolution reaction (HER). These findings suggest a wide range of technological applications, from nanoelectronics and nanomechanics to metal-free catalysis in sustainable energy production.
Emergence of temporal noise hierarchy in co-regulated genes of multi-output feed-forward loop
Authors: Nandi Mintu 
Published: November 2024

Abstract
Natural variations in gene expression, called noise, are fundamental to biological systems. The expression noise can be beneficial or detrimental to cellular functions. While the impact of noise on individual genes is well-established, our understanding of how noise behaves when multiple genes are co-expressed by shared regulatory elements within transcription networks remains elusive. This lack of understanding extends to how the architecture and regulatory features of these networks influence noise. To address this gap, we study the multi-output feed-forward loop motif. The motif is prevalent in bacteria and yeast and influences co-expression of multiple genes by shared transcription factors (TFs). Focusing on a two-output variant of the motif, the present study explores the interplay between its architecture, co-expression (symmetric and asymmetric) patterns of the two genes, and the associated noise dynamics. We employ a stochastic modeling approach to investigate how the binding affinities of the TFs influence symmetric and asymmetric expression patterns and the resulting noise dynamics in the co-expressed genes. This knowledge could guide the development of strategies for manipulating gene expression patterns through targeted modulation of TF binding affinities.
Planar structure of organic photodetector for low dark current
Authors: Nofil Mohammad , Md Sabri Amirul Ashraf , Natashah Fadlan Arif , Bawazeer Tahani M , Alsoufi Mohammad S , Roslan Nur Adilah , Supangat Azzuliani 
Published: November 2024

Abstract
The focus of this study is on investigating the vanadyl 2,9,16,23-tetraphenoxy-29H, 31H-phthalocyanine (VOPcPhO) and its blend with o-xylenyl C60 bis-adduct (OXCBA), for use as a lateral ultraviolet organic photodetector. The research focuses on improving dark current reduction, which is a challenge in lateral organic photodetector. By integrating the OXCBA, low dark current values of 4.83 nA⋅cm−2 (

D

shot

*

=
1.414
×

10

11

Jones

) have been achieved as compared to the stand-alone VoPcPhO device of 14.06 nA⋅cm−2. The major contributing factors to dark current reduction are due to the efficient charge transfer at the photoactive-electrode interface, the deep highest occupied molecular orbital (HOMO) level of OXCBA, which leads to favorable energy level alignments hindering hole injection, and the occurrence of bulk heterojunction vertical phase segregation between VOPcPhO and OXCBA. These findings shed light on the relationship between the organic photoconductor’s material composition, morphology, and performance metrics and open new avenues for metal phthalocyanine-based lateral ultraviolet organic photodetectors with low dark current and enhanced performance.
Moderate electron–spin interaction in Fe-intercalated NbSe2
Authors: Liu 刘 Qiao-Yu 乔宇 , Bai 白 Jian-Li 建利 , Dong 董 Qing-Xin 庆新 , Zhang 张 Li-Bo 黎博 , Cheng 程 Jing-Wen 靖雯 , Liu 刘 Pin-Yu 品宇 , Li 李 Cun-Dong 存东 , Huang 黄 Yu 宇 , Sun 孙 Ying-Rui 英睿 , Ren 任 Zhi-An 治安 , Chen 陈 Gen-Fu 根富 
Published: November 2024

Abstract
The interaction between charge and spin degrees of freedom has always been the central issue of condensed matter physics, and transition metal dichalcogenides (TMDs) provide an ideal platform to study it benefiting from their highly tunable properties. In this article, the influence of Fe intercalation in NbSe2 was elaborately investigated using a combination of techniques. Magnetic studies have shown that the insertion of Fe atoms induces an antiferromagnetic state in which the easy axis aligns out of the plane. The sign reversal of the magnetoresistance across the Neel temperature can be satisfactorily explained by the moderate interaction between electrons and local spins. The Hall and Seebeck measurements reveal a multi-band nature, and the contribution of various phonon scattering processes is discussed based on the thermal conductivity and specific heat data.
Multi-layer ear-scalp distillation framework for ear-EEG classification enhancement
Authors: Sun Ying , Zhang Feiyang , Li Ziyu , Liu Xiaolin , Zheng Dezhi , Zhang Shuailei , Fan Shangchun , Wu Xia 
Published: November 2024

Abstract

B
a
c
k
g
r
o
u
n
d
.

Ear-electroencephalography (ear-EEG) holds significant promise as a practical tool in brain–computer interfaces (BCIs) due to its enhanced unobtrusiveness, comfort, and mobility compared to traditional steady-state visual evoked potential (SSVEP)-based BCI systems. However, achieving accurate SSVEP classification with ear-EEG remains a major challenge due to the significant attenuation and distortion of the signal amplitude.

O
b
j
e
c
t
i
v
e
.

Our aim is to enhance the classification performance of SSVEP using ear-EEG and to increase its practical application value.

A
p
p
r
o
a
c
h
.

To address this challenge, we focus on enhancing ear-EEG feature representations by training the model to learn features similar to those of scalp-EEG. We introduce a novel framework, termed multi-layer ear-scalp distillation (MESD), designed to optimize SSVEP target classification in ear-EEG data. This framework combines signals from the scalp to obtain multi-layer distilled knowledge through the cooperation of mid-layer feature distillation and output layer response distillation.

M
a
i
n

r
e
s
u
l
t
s
.

We improve the classification of the initial 1 s data and achieved a maximum classification accuracy of 81.1%. We evaluate the proposed MESD framework through single-session, cross-session, and cross-subject transfer decoding, comparing it with baseline methods. The results demonstrate that the proposed framework achieves the best classification results in all experiments.

S
i
g
n
i
f
i
c
a
n
c
e
.

Our study enhances the classification accuracy of SSVEP based on ear-EEG within a short time window. These results offer insights for the application of ear-EEG brain–computer interfaces in tasks such as auxiliary control and rehabilitation training in future endeavors.
Intra-urban variations in land surface phenology in a semi-arid environment
Authors: Crawford Ben , Kelsey Kathy , Ibsen Peter , Rees Amanda , Charobee Amanda 
Published: November 2024

Abstract
Urban vegetation is growing in importance as cities use ‘green infrastructure’ to mitigate the impacts of climate change, reduce extreme heat, and improve human health and comfort. However, due to the heterogeneity of city landscapes, urban vegetation experiences a diverse range of environmental conditions, potentially leading to differences in growing season timing and length within cities. Here, we investigate physical drivers of urban land surface phenology and timing within a semi-arid city (Denver, CO, USA) using four years (2018–2021) of remotely sensed vegetation indices, modelled air temperature, and land cover datasets. Within the metropolitan region study area, satellite-based vegetation index measurements indicate that growing season length is variable on sub-neighborhood spatial scales. This variability is largely due to differences in the timing of fall senescence, as opposed to early season growth. Areas with substantial fractions of irrigated land cover tend to remain greener for longer, while unirrigated and cooler areas are correlated with an earlier end to the growing season (up to ∼two months shorter). These findings complement those from non-arid cities where surface and air temperature are the dominant environmental control on phenological timing. Results here indicate the importance of soil moisture for phenology in semi-arid regions and suggest unique semi-arid urban growing season dynamics and temperature-vegetation feedbacks. These interactions have implications for water, heat, and vegetation management strategies to maximize ecosystem services in water-limited environments.
Current fluctuations of a self-interacting diffusion on a ring
Authors: Coghi Francesco 
Published: November 2024

Abstract
We investigate fluctuations in the average speed or current of a self-interacting diffusion (SID) on a ring, mimicking the non-Markovian behaviour of an agent influenced by its own path. We derive the SID’s phase diagram, showing a delocalisation-localisation phase transition from self-repelling to self-attracting. Current fluctuations are analysed using: (i) an adiabatic approximation, where the system reaches its stationary distribution before developing current fluctuations, and (ii) an original extension of level 2.5 large deviations for Markov processes combined with perturbation theory. Both methods provide lower bounds to current fluctuations, with the former tighter than the latter in all localised regimes, and both equally tight in the self-repelling region. Both methods accurately estimate the asymptotic variance and suggest a phase transition at the onset of the localised regime.
Modern Sources of Controls in Case-Control Studies
Authors: Banack Hailey R , Fox Matthew P , Platt Robert W , Garber Michael D , Li Xiaojuan , Schildcrout Jonathan , Matthay Ellicott C 
Published: November 2024

Abstract
In 1992, Wacholder and colleagues developed a theoretical framework for case-control studies to minimize bias in control selection. They described three comparability principles (study base, deconfounding, and comparable accuracy) to reduce the potential for selection bias, confounding, and information bias in case-control studies. Wacholder et al. explained how these principles apply to traditional sources of controls for case-control studies, including population controls, hospital controls, controls from a medical practice, friend or relative controls, and deceased controls. The goal of the current manuscript is to extend this seminal work on case-control studies by providing a modern perspective on sources of controls. Today, there are many more potential sources of controls for case-control studies than there were in the 1990s. This is due to technological advances in computing power, internet access, and availability of ‘big data’ resources. These advances have vastly expanded the quantity and diversity of data available for case-control studies. In this manuscript, we discuss control selection from electronic health records, health insurance claims databases, publicly available online data sources, and social media-based data. We focus on practical considerations for unbiased control selection, emphasizing the strengths and weaknesses of each modern source of controls for case-control studies.
STRprofiler: efficient comparisons of short tandem repeat profiles for biomedical model authentication
Authors: Andrews Jared M , Lloyd Michael W , Neuhauser Steven B , Bundy Margaret , Jocoy Emily L , Airhart Susan D , Bult Carol J , Evrard Yvonne A , Chuang Jeffrey H , Baker Suzanne 
Published: November 2024

Abstract

Summary
Short tandem repeat (STR) profiling is commonly performed for authentication of biomedical models of human origin, yet no tools exist to easily compare sets of STR profiles to each other or an existing database in a high-throughput manner. Here, we present STRprofiler, a Python package, command line tool, and Shiny application providing methods for STR profile comparison and cross-contamination detection. STRprofiler can be run with custom databases or used to query against the Cellosaurus cell line database.

Availability and implementation
STRprofiler is freely available as a Python package with a rich CLI from PyPI https://pypi.org/project/strprofiler/ with source code available under the MIT license on GitHub https://github.com/j-andrews7/strprofiler and at https://zenodo.org/records/10989034. A web server hosting an example STRprofiler Shiny application backed by a database with data from the National Cancer Institute-funded PDXNet consortium and The Jackson Laboratory PDX program is available at https://sj-bakerlab.shinyapps.io/strprofiler/. Full documentation is available at https://strprofiler.readthedocs.io/en/latest/.
Application of prelithiated nanoporous carbon anode for high-power lithium-ion capacitor
Authors: Okabe Jugo , Notohara Hiroo , Urita Koki , Moriguchi Isamu 
Published: November 2024

Abstract
Prelithiated nanoporous carbons were applied as an anode material in lithium-ion capacitors to achieve high-power performance. Nanoporous carbon anodes with different pore structures, graphitization degrees, and prelithiation conditions were comparatively investigated for their rate performance, self-discharge property, and full-cell performance. Prelithiated nanoporous carbon anode prepared under optimized condition exhibited high power and energy densities.
Preoperative evaluation of lingual cortical plate thickness and the anatomical relationship of the lingual nerve to the lingual cortical plate via 3T MRI nerve-bone fusion
Authors: Jiang Dongmei , Hong Junhuan , Yan Yalan , Huang Hao , You Peiying , Huang Weilin , Zhao Xiance , She Dejun , Cao Dairong 
Published: November 2024

Abstract

Objectives
To evaluate the reliability of 3T MRI nerve-bone fusion in assessing the lingual nerve (LN) and its anatomical relationship to the lingual cortical plate prior to the impacted mandibular third molar (IMTM) extraction.

Methods
The MRI nerve and bone sequences used in this study were 3D T2-weighted fast field echo (3D-T2-FFE) and fast field echo resembling a CT using restricted echo-spacing (FRACTURE), respectively. Both sequences were performed in 25 subjects, and the resulting 3D-T2-FFE/FRACTURE fusion images were assessed by 2 independent observers. Semi-quantitative analyses included assessments of overall image quality, image artefacts, nerve continuity, and the detectability of 5 intermediate points (IPs). Quantitative analyses included measurements of the lingual cortical plate thickness (LCPT), vertical distance (V1* and V2*), and the closest horizontal distance (CHD) between the LN and the lingual cortical plate. Reliability was evaluated using weighted Cohen’s kappa coefficient (κ), intraclass correlation coefficient (ICC), and Bland-Altman plots. Differences in LCPT between 3D-T2-FFE/FRACTURE fusion images and cone-beam computed tomography (CBCT) were compared using independent samples t-tests or Mann-Whitney U tests.

Results
The fusion images demonstrated that the LN continuity score was 3.00 (1.00) (good), with 88% (44/50) of LNs displayed continuously at the IMTM level. Intra-reader agreement for nerve continuity was moderate (κ = 0.527), as was inter-reader agreement (κ = 0.428). The intra-reader and inter-reader agreement for LCPT measurements at the neck, mid-root, and apex of the IMTM were all moderate (ICC &gt; 0.60). Intra-reader agreements for V1*, V2*, and CHD were moderate to excellent (ICC = 0.904, 0.967, and 0.723, respectively), and inter-reader agreements for V1*, V2*, and CHD were also moderate to excellent (ICC = 0.948, 0.941 and 0.623, respectively). The reliability of LCPT measurements between 3D-T2-FFE/FRACTURE fusion and CBCT was moderate (ICC = 0.609-0.796).

Conclusions
The 3D-T2-FFE/FRACTURE fusion technique demonstrated potential feasibility for the identification of the LN and its relationship to the lingual cortical plate, as well as for the measurement of LCPT. This study has generated a dataset that is capable of simultaneously defining the LN and LCPT.
High prevalence of esophageal motility disorders in patients with rheumatologic diseases
Authors: Reddy Sumana , Patel Beyla , Dellon Evan S , Eluri Swathi 
Published: November 2024

Summary
While it is commonly known that patients with rheumatologic diseases can have esophageal dysfunction, this association is insufficiently understood. The aim is to determine the prevalence and characteristics of esophageal motility disorders in patients with rheumatic diseases. This is a single-center retrospective study of adults with rheumatologic disease who underwent high-resolution esophageal manometry (HREM). Those with and without a motility disorder (defined per Chicago classification CCv3.0 criteria, given the timing of the prior studies) were compared and multivariable logistic regression was used to determine odds of motility disorder by rheumatic disease. Of 289 patients, the mean age was 60.5 ± 13.8 years. Rheumatic diseases included Raynaud’s (42%), rheumatoid arthritis (RA) (39%), Sjogren’s (21%), systemic lupus erythematous (19%), systemic sclerosis (17%), and mixed connective tissue disease (13%). On HREM, 58% had an esophageal motility disorder: achalasia (5%), EGJ outflow obstruction (20%), jackhammer (8%), diffuse esophageal spasm (1%), ineffective esophageal motility (28%), and fragmented peristalsis (2%). Of note, 50% of the sample with a normal barium swallow had an esophageal dysmotility disorder on HREM. Those with psoriatic arthritis were less likely to have esophageal dysmotility (73% vs. 27%; P = 0.04). There was decreased odds of esophageal hypocontractility in those with RA (OR [95%CI]: 0.27 [0.12–0.58]) and increased odds (OR [95%CI]: 3.13 [1.16–8.41]) of esophageal hypocontractility among those with scleroderma. Esophageal motor disorders were found in more than half of patients with rheumatologic diseases who underwent HREM. HREM should be considered in patients with rheumatic conditions presenting with esophageal symptoms.
Democracia global y Estados no representativos
Authors: Kristan M Victoria 
Published: November 2024

Abstract
Can the current international system provide sufficient protection for individual freedom in a globalized world? This article aims to show that only a legitimate international system could offer such protection. However, the current international system lacks legitimacy because it is composed of a large number of non-representative states that dominate their people. Consequently, this paper analyzes the possibility of international interventions as a means to transform non-democratic states into democratic ones, based on the distinction between dominating and non-dominating interventions, according to whether the freedom as status is compromised, and in turn between interventions that strengthen and weaken global democracy.
Development of High-Titer Antidrug Antibodies in a Phase 1b/2a Infant Clesrovimab Trial Are Associated With RSV Exposure Beyond Day 150
Authors: Thambi Nithya , Phuah Jia Yao , Staupe Ryan P , Tobias Lori M , Cao Yu , McKelvey Troy , Railkar Radha A , Aliprantis Antonios O , Arriola Carmen Sofia , Maas Brian M , Vora Kalpit A 
Published: November 2024

Abstract

Background
Clesrovimab is a human half-life–extended monoclonal antibody in phase 3 evaluation for the prevention of respiratory syncytial virus (RSV) disease in infants. Antidrug antibodies (ADA) were observed at late time points in a phase 1b/2a study where clesrovimab was well tolerated with an extended half-life of approximately 45 days.

Methods
Serum samples at days 150, 365, and 545 postdose were assayed for ADA titers. Samples with high ADA titers were characterized for their binding specificity to the Fab or the YTE portion of clesrovimab. RSV serum neutralization (SNA) titers were also measured on ADA-positive and ADA-negative infants. Additionally, a D25 (site Ø) competitive enzyme-linked immunosorbent assay (ELISA) was performed on ADA-positive available samples to determine RSV exposure. Local surveillance data was used to ascertain RSV circulation during the trial.

Results
High ADA titers were observed in a minority of infants at days 365 and 545 for all doses tested. Additionally, all high-titer ADA-positive infants had ADA directed towards the YTE epitope of clesrovimab. Moreover, these infants demonstrated robust RSV-SNA and had D25 competitive antibodies suggesting an RSV exposure after day 150, coinciding with the epidemiological data.

Conclusions
RSV exposure in infants beyond day 150 after dosing is associated with ADA development and high RSV-SNA titers with no impact on pharmacokinetics.

Clinical Trials Registration
NCT03524118.
Norovirus Surveillance and Outbreak Investigations in Peru: 25 Years of Experience at NAMRU SOUTH
Authors: Neyra Joan , Gonzales Miriam , La Rosa Sayda , Ponce Diana , Tecco Anilu , Romero Candice , Soto Giselle 
Published: November 2024

Abstract
Norovirus is the worldwide leading cause of gastroenteric diseases. It affects mainly infants and older adults, but the findings are mainly derived from outbreak investigations rather than population-based cohorts. The U. S. Naval Medical Research Unit SOUTH (NAMRU SOUTH) developed and conducted research studies in the last 20 years focusing on the military and general populations afflicted by this pathogen. For the latter, studies included all age groups in 2 main communities in Peru, representing people from the highlands and tropical areas. The results helped elucidate the incidence of norovirus infection among different age groups as well as identifying risk factors, seasonality, and economic burden on the patient. The collected data demonstrate an increase of norovirus cases, not only in the previously reported age groups but also in adults. Consequently, this increase of norovirus cases in adults may impair the occupational productivity in civilian populations and operational readiness among service members.