bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vaidya Brahmasree O. Kesavan Nadar Swami: The pioneer who has elevated the prominence of Marma Sastra in the curriculum of Ayurveda
Authors: Chandrika Soumya Mohanan , Peethambaran Sinimol Thekkekkottumughath , Nalinakshan Sreedeepthi Girija 
Published: November 2024

Abstract
This article aims to bring up the professional reminiscences of the great Ayurvedic luminary Brahmasree O. Kesavan Nadar Swami. He was an outstanding Kalari (one of the martial arts of Kerala) and Marma (traditional science dealing with vital energy points of the body) practitioner who lived in the Indian princely state of Travancore of southern India during the era of His Highness Maharaja Sree Chithira Thirunal Balarama Varma. He flourished to be an eminent scholar of Agasthya Marmasastra. Considering his excellence as a Marma practitioner, he was appointed as a “Granted physician” to the Royal family of Travancore, and he continued his journey as a Marma Vaidya (physician) of the Government Ayurveda College, Thiruvananthapuram, and retired as the Chief Marma physician. The anecdote collected through his descendants is being published to shed light on his life profile and bring this eminent personality’s memoir to the mainstream.
Arya Vaidyan N Rama Varier: Proponent of Ayurveda traditions in Tami Nadu
Authors: Kusuma Ganji , Pattona Aswathi Mohan , Ilavarasan Raju 
Published: November 2024

Abstract
Arya Vaidyan N. Rama Varier, the founder of Arya Vaidya Nilayam (AVN), was born in 1903 in South Malabar in the Madras Presidency. He studied Ayurveda at Arya Vaidya Patashala, Kottakkal. He was among the first few disciples of Late Vaidyaratnam P.S. Varier, a legendary figure in the field of Ayurveda from Kottakkal, Kerala. After relocating to Madurai, Tamil Nadu, he established a clinic with a modest capital and prepared medicines for his practice. His effective treatment and compassion for patients made him a popular physician in the area. He established AVN in 1930, popularizing authentic Ayurveda in Madurai and its surroundings. Varier took the initiative to develop the Ayurveda system in Tamil Nadu and was awarded the title of “Ayurveda Vachaspati” by the Madurai Swadeshi Vaidya Sabha in recognition of his meritorious services to Ayurveda and humanity. Arya Vaidyan N. Rama Varier inspired people from all walks of life to strive for excellence and make a positive impact on the world.
Comparison of the effect of self-care education with two methods, teach-back and smartphone application, on the adherence to treatment in patients with inflammatory bowel disease
Authors: Manzari Zahra Sadat , Ghaderi Mohammad Sajjad , Vossoughinia Hassan , Rafiei Hossein , Mafi Mohamad Hossein 
Published: November 2024

Abstract

Background:
Self-care is one of the basic principles in the management of chronic diseases, which influences follow-up and adherence to treatment. Therefore, the current study was conducted with the aim of comparing the effect of teach-back (TB) and a smartphone application on adherence to treatment in patients with inflammatory bowel disease (IBD).

Methods:
The current clinical trial was conducted among 80 patients with IBD in Mashhad, Iran, in 2021–2022. Self-care education (diet, personal and social relationships, medications, sleep, physical activity, sexual relationships, etc.) was provided through TB method in one group and by using a smartphone application in another group. The control group only received the routine education. A checklist for demographic information and the adherence questionnaire in patients with chronic diseases were used for data collection.

Results:
Patients’ mean age was 38.73 ± 10.32 years. The majority of patients had ulcerative colitis (81%) and were married (67%). Mean and standard deviation score of adherence to treatment were the same in all three groups before the intervention (P = 0.668). The mean post-test scores of adherence to treatment in the TB, application, and control groups were 170.04 ± 14.19, 167.99 ± 11.59, and 159.60 ± 10.94, respectively. The difference was statistically significant (P = 0.003). A significant difference was observed in regards to the mean post-test scores of adherence to treatment between TB and control groups (P = 0.004) and app and control groups (P = 0.048). However, the difference between TB and app groups was not significant (P = 0.989).

Conclusions:
TB method and smartphone application have the same effect on adherence to treatment in patients with IBD. Due to the usability and cost-effectiveness of smartphone applications, this method can be used by health-care providers to educate this group of patients.
Minimally Invasive Techniques in Radical Cystectomy: Is It Justified
Authors: Kaul Naresh Kumar , Narain Tushar Aditya 
Published: November 2024

Summary
Over the past two decades there has been a gradual shift towards the use of minimally invasive radical cystectomy in the surgical management of muscle invasive bladder cancer. Though there has been some reluctance in the use of intracorporeal diversion, with advent of robotic technology most high volume centres are performing completely minimally invasive radical cystectomy. Most studies show similar oncological efficiency between minimally invasive techniques and open techniques with lesser complications and hospital stay as well as better quality of life measures. In this chapter we try to compare minimally invasive techniques with open techniques and justify the use of minimally invasive radical cystectomy more so with intracorporeal diversion.
Muscle-invasive Bladder Cancer: How to Select Patients for Neoadjuvant Chemotherapy
Authors: Xing Eunice Yun , Sarwar Naveed 
Published: November 2024

Summary
Approximately 25% of patients with bladder cancer present with muscle-invasive disease. International guidelines recommend cisplatin-based neoadjuvant chemotherapy (NAC) for patients suitable for radical treatment. However, appropriate candidate selection for NAC is crucial to ensure that the benefits outweigh potential toxicities and delays to radical cystectomy (RC). Patients should meet eligibility criteria for cisplatin therapy, and factors such as age, comorbidities, and nutritional status should be evaluated in conjunction. Timely initiation of NAC following diagnosis is essential. The use of NAC for T2 tumors and variant histology remains contentious. It is important to recognize that disease often undergoes upstaging post-RC, and variant histologies are associated with more aggressive clinical courses. These factors necessitate an individualized assessment to determine the appropriateness of NAC. Although biomarkers are not yet routinely used, they may play a pivotal role in optimizing patient selection for NAC in the near future.
Ovarian Toxicity Linked to Early-stage Breast Cancer Treatment
Authors: Echavarria Isabel , Jerez Yolanda , Bringas Marianela , López-Tarruella Sara , Martin Miguel 
Published: November 2024

Abstract
Breast cancer (BC) is the most diagnosed cancer in young women. Advances in treatment have significantly improved long-term outcomes. In modern societies, many women are delaying childbirth, leading to a growing number of BC survivors who want to have children after their treatment. Fertility concerns are crucial for young BC patients, impacting their treatment decisions and adherence. The treatment for early-stage BC is complex and includes various therapies such as chemotherapy, endocrine therapy, anti-HER2 therapies, immunotherapy, and targeted agents. All of these treatments carry the potential risk of damaging the ovaries and causing fertility issues, which need to be carefully evaluated. In this review, we will explore the risk of ovarian damage associated with BC treatments, including newer agents such as CDK4/6 and Poly (ADP-ribose) Polymerases (PARP) inhibitors, as well as immunotherapy, along with recommendations for an accurate assessment regarding the risk of gonadotoxicity.
Богословие времени преподобного Максима Исповедника и причинная механика Н. A. Козырева (1908–1983)
Authors: В. В. Василик 
Published: November 2024

В статье рассматривается богословие времени преподобного Максима Исповедника в сравнении с т. н. причинной механикой астронома Н. А. Козырева (1908–1983). В учении преподобного Максима существуют две категории темпоральности: καιρός, отвечающая за дискретное, конечное, тленное время, и αἰὼν («век»), отражающая время, устремленное в вечность, сохраняющее, обновляющее и животворящее мир. В причинной механике Н. А. Козырева существует понятие хода времени, «плотности времени», представление о том, что время вносит в мир (прежде всего в звезды) энергию и обновляет его. Богословие эона преподобного Максима Исповедника и теория времени Н. А. Козырева обладают значительным сходством в представлении о времени как о некоем активном начале, организующим процессы этого мира и создающим причинно-следственные связи, обновляющим и животворящим мир, обладающим своим «ходом», то есть энергией, обладающим своей плотностью, подобно «одебелевшим», «уплотненным» логосам. Ряд духовных процессов, в частности интуиция, связаны со временем, организующим причинно-следственные связи.
The article examines the theology of time of St. Maximus the Confessor in comparison with the so-called causal mechanics of the astronomer N. A. Kozyrev (1908–1983). In the teachings of St. Maximus, there are two categories of temporality: καιρός, responsible for discrete, finite, perishable time, and αἰὼν (“century”), reflecting time directed toward eternity, preserving, renewing, and life-giving the world. In the causal mechanics of N. A. Kozyrev, there is a concept of the passage of time, “the density of time,” the idea that time brings energy into the world (primarily into the stars) and renews it. The theology of aeon of St. Maximus the Confessor and the theory of time of N. A. Kozyrev have significant similarities in the idea of time as a certain active principle, organizing the processes of this world and creating cause-and-effect relationships, renewing and life-giving the world, possessing its own “course”, that is, energy, possessing its own density, like “obese”, “densified” logoi. A number of spiritual processes, in particular intuition, are associated with time, organizing cause-and-effect relationships.
«Богоматерь Умиление с пророками и святыми женами» из Белозерска: палеографический и графикоорфографический анализ надписей на иконе
Authors: К. С. Гулидова , А. А. Макарова 
Published: November 2024

Икона «Богоматерь Умиление» («Белозерская»), хранящаяся в Государственном Русском музее — известный памятник древнерусского домонгольского искусства. В обширной библиографии, посвященной этому уникальному образу, рассматривались вопросы, связанные со стилистическими и иконографическими особенностями, исследовалась история его бытования. Между тем, памятник сохранил первоначальные именующие надписи, которые до сих пор не привлекали внимание филологов. В статье предпринята попытка восполнить этот пробел. Надписи рассмотрены с точки зрения палеографических и графико-орфографических особенностей.
The monumental icon titled, “Our Lady of Tenderness” (“Belozerskaya”), which is in the collection of the State Russian Museum, is a famous example of ancient, pre-Mongol, Russian art. An extensive bibliography dedicated to this unique image examines issues related to its stylistic and iconographic features and explores the history of its existence. Meanwhile, this monumental icon has preserved the original naming inscriptions, which have not yet attracted the attention of philologists. This article attempts to fill this gap. The inscriptions are considered from the point of view of paleographic and graphico-orthographic features.
Возможно ли богословие эволюции? Рецензия на книгу: Russo M. A. Evolutionary History in Theological Perspective Exploring the Scientific Story of the Cosmos. NY; London: Lexington Books/Fortress Academic, 2024. 191 p.
Authors: Д. В. Кирьянов 
Published: November 2024

Эволюционная биология стала неотъемлемой частью научной картины мира. Огромный массив данных, полученных физическими, химическими и биологическими науками, свидетельствует об эволюции космоса и жизни. Являются ли попытки секулярного осмысления космической и биологической эволюции успешными? Может ли христианское богословие придать смысл всей космической истории и ответить на те вопросы, которые не могут быть решены в рамках секулярных подходов? Насколько удачными являются попытки построения богословия эволюции? В настоящей статье представлен анализ ключевых богословских идей теистического эволюционизма в попытке придать смысл эволюции космоса и жизни.
Evolutionary biology is an integral part of contemporary science. Vast amounts of data from physical, chemical and biological sciences provide evidence to cosmic and biological evolution. But question arises: can secular understanding of cosmic and biological evolution give sense to its whole history and meaning of human life? Can Christian theology give sense to the entire cosmic history and answer those questions that cannot be resolved within the framework of secular approaches? How successful are attempts to build theology of evolution? This article presents an analysis of the key theological ideas of theistic evolutionism in an attempt to make sense of the evolution of the cosmos and life.
The Power of Overconfidence and Herding Bias, Investment Sentiment, Over/Underreaction in Influencing SDGs from Investment Decisions
Authors: Wijaya Liliana Inggrit , Sutejo Bertha Silvia , Tanumulya Gerard Nico 
Published: November 2024

Objective: The era of globalization makes investment activities in Indonesia easier with many digital platforms. The number of investors also increases every year because many people are starting to realize the importance of investing. In addition, it is also necessary to understand how to maintain SDGs from these investment decisions. This study aims to test the strength of overconfidence, herding bias, investment sentiment, and over/under reaction in influencing investment decisions in Indonesia.

Method: This research is explanatory research with primary data. Primary data was obtained by distributing questionnaires to 350 investors in Indonesia from December 2023 to February 2024. Hypothesis testing in this research used Structural Equation Modelling (SEM) with SmartPLS3 software.

Results and Discussion: The findings of this study reveal that overconfidence, investor sentiment, and over/underreaction all have a significant favorable impact on investing decisions. Meanwhile, herding bias no has effect on investment decisions. The prospect theory posits that humans choose among numerous alternatives based on the likelihood of upcoming or known dangers, supporting H1's findings. Meanwhile, H3 and H4 are based on behavioral finance theory, which describes how psychological aspects influence investing decisions. The MGA analysis of age, gender, and education level can substantially impact the relationship between overconfidence, herding, investing sentiment, and over/underreaction to investment decisions. MGA analysis of age, gender, and education level can substantially impact the relationship between overconfidence, herding, investing sentiment, and over/underreaction to investment decisions.

Originality/Value: This study emphasizes novelty by expanding the discussion on investment decisions with multigroup analysis. Multigroup analysis is an added value because it sees the influence of overconfidence, investor sentiment, and over/underreaction on investment decisions more specifically related to demographic factors, namely age, gender, and education level.
Clinical Data Standards and Data Anonymization Considerations for Academic Organizations: International Cross-Sectional Survey
Authors: Gaudesi Davide , Ittenbach Richard , Cameron Stephen , Yu Hong , Adegoke Olusegun , Miyaji Tempei , Bragat Alexander John Ching , Rostami Reza 
Published: November 2024

Introduction: Clinical Data Management (CDM) is a critical aspect of clinical research, and the use of clinical data standards is essential to ensure the quality and consistency of one’s data.
Objectives: We aim to obtain a snapshot of practice patterns among CDM professionals at academic institutions regarding the implementation and use of clinical data standards.
Methods: A survey of 14 questions on clinical data standards and anonymization was sent to over 300 academic clinical institutions worldwide. Data were obtained from a total of 50 institutions.
Results: Sixty-six percent of institutions reported implementing data standards while only 22% of reporting institutions offered data standards training and 20% offered training in anonymization. The findings presented here will be useful to research administrators striving to improve upon and streamline the use, implementation, and training of clinical data standards in academic research today.
Trendek, kihívások és válaszok a szemészeti ellátás közfinanszírozásában 2008-tól napjainkig, Magyarországon
Authors: Dózsa Csaba , Tóth Melanie , Sipos István , Cseh Borbála 
Published: November 2024

A szemészeti ellátás nem tartozik a kiemelt prioritású egészségügyi ellátások közé (nem szerepel a haláloki statisztikában) mégis szinte mindenki életében idővel nagy szerepet játszik az életminőség megőrzésében az életkor előrehaladtával. Közép-Kelet-európai egyetemek kutatói a Visegrad Fund (V4) keretében pályázott kis összegű támogatásból 2010-2021. között a Visegrádi országokra vonatkozóan szisztematikus elemzést végeztek és összehasonlították a szemészeti ellátások finanszírozási módszereit és trendjeit. Az elemzések 6 féle szembetegségre, illetve kezelésre terjedtek ki: szürkehályog (cataracta) műtétek, zöldhályog (glaucoma) kezelés, időskori makula degeneráció (AMD), cukorbeteg (diabetic) makula ödéma (DME) kezelése (intravitrealis injekciók), vitrectomia (PPV), valamint szaruhártya átültetés (KP, cornea transzplantáció). Az elemzések egyik fő célja az volt, hogy megfelelő tanulságokkal, jó gyakorlatokkal szolgáljanak ukrán finanszírozási szakemberek számára, akik hasonló finanszírozási és ellátásfejlesztési programon dolgoznak. Jelen tanulmány célja annak bemutatása, hogy a szemészeti ellátások területén a projekt keretében milyen meghatározó trendeket, kihívásokat tártunk fel a visegrádi országokban, és ez alapján milyen egészségpolitikai és egészségbiztosítási finanszírozási feladatokat fogalmazhatunk meg a döntéshozók számára Magyarországon a következő évekre vonatkozóan.
Betegkockázatok csökkentésének folyamata egy laboratóriumi hálózatban
Authors: Szlatinszki Nóra , Barna T. Katalin , Csernák Zsolt 
Published: November 2024

Az egészségügyi szolgáltatók hatékony működése megköveteli tevékenységük folyamatos elemzését, javítását és fejlesztését. A SYNLAB Hungary Kft. 2013-ban célul tűzte ki a betegbiztonság növelését, majd 2017-ben munkacsoportot indított a kritikus betegállapotot jelző laboratóriumi eredmények kezelésének hálózaton belüli egységesítésére. A betegbiztonsággal kapcsolatos kockázatokat Failure Mode and Effects Analysis módszer alkalmazásával becsültük meg és hasonlítottuk össze. Célkitűzésünk volt, hogy a laboratóriumok a kritikus kockázatot jelző laboratóriumi eredmények kezelésének (KKE) folyamatát indikátorokkal monitorozzák. A KKE-k közlésének megbízhatósága érdekében teljesítmény célokat fogalmaztunk meg. Mindkét indikátor esetében célnak tűztük ki az eredmények 100%-ának sikeres, és a lehető legrövidebb időn belül történő közlését a felelős ellátó felé (az ellenőrzést követő nem több, mint 1 órán belül). A dunaújvárosi laboratóriumban a 2017-2021 közötti időszakban, összesen 13198 riasztási eredmény közlési körülményeit vizsgálták: ebből sikeres volt 12574 (megbízhatóság 95%). Mivel a riasztási eredmények felesleges ismétlése a leletkiadást késlelteti, ezáltal betegbiztonsági kockázatot jelent. A dunaújvárosi laboratórium 30 hónap alatt összesen 1844 megismételt riasztási eredményt vizsgált meg a Clinical Laboratory Improvement Amendments nemzetközi ajánlása alapján a megengedhető totális hiba nagyságára nézve. Ebből 929 hematológiai, 915 pedig kémiai vizsgálat volt. Tanulmányunk eredményei alapján elmondhatjuk, hogy elsősorban azokat az eredményeket szükséges megismételni, amelyek a delta ellenőrzés alapján (kritikus vagy jelentős differencia) nem korrelálnak a páciens korábbi, vagy jelenlegi állapotával. A delta ellenőrzést vagy az automatának, vagy az informatikai rendszernek kell biztosítani. Mindezen intézkedésekkel a KKE-k kezelésével kapcsolatos betegkockázatok csökkenthetőek, az FMEA tábla használatával pedig a maradék kockázatok is nyomon követhetőek a folyamatos fejlesztés érdekében.
ЦИФРОВАЯ ТРАНСФОРМАЦИЯ ТРАНСПОРТНО-ЛОГИСТИЧЕСКИХ СИСТЕМ ПОСТАВОК
Authors: Ю.А. Маликова 
Published: November 2024

В настоящее время после того как российские транспортно-логистические цепочки были перестроены с Запада на Восток, на страницах печати и в выступлениях экспертов прослеживается мнение о том, что новые системы поставок преодолели негативные тенденции и вышли на траекторию устойчивого развития. Однако, если обратиться к цифровым составляющим сложившихся сегодня транспортно-логистических систем, не трудно усмотреть ситуации, требующие решения целого ряда структурных проблем, включая инициативы по внедрению новейших технологий и построение инновационных экосистем для объединения участников рынка транспортно-логистических услуг. В статье предпринята попытка исследовать данные вопросы.At present after Russian transport and logistics chains have been rebuilt from West to East, there is an opinion in the press and in expert speeches that new supply chains have overcome negative trends and entered a sustainable development trajectory. However, if we turn to the digital components of today's transport and logistics systems, it is not difficult to see situations that require solving a number of structural problems, including initiatives to introduce the latest technologies and build innovative ecosystems to unite participants in the transport and logistics services market. The article attempts to explore these issues.
НОВЫЕ КОНТУРЫ МИРОВОГО ПОРЯДКА: ГЛОБАЛЬНАЯ ТРАНСФОРМАЦИЯ И СТРАНЫ АФРИКИ
Authors: О.А. Миронова 
Published: November 2024

В статье рассматривается современное положение стран Африканского континента, их ресурсное обеспечение, проблемы и перспективы в условиях современной глобальной трансформации и формирования контуров нового миропорядка. На основе анализа перспектив формирования многополярного полицентричного мира по мере выхода мир-системы из состояния бифуркации автор предполагает, что для Африки большую вероятность представляет попадание в зону неоколониальных интересов одного из потенциальных полюсов, чем превращение в самостоятельный полюс. Делается вывод о важности сотрудничества между Россией и Африкой, которое может помочь странам Черного континента в обретении своей идентичности и консолидации на основе панафриканской идеи.
Article examines the current situation of countries of African continent, their resource provision, problems and prospects in context of modern global transformation and formation of contours of new world order. Based on analysis of prospects for formation of multipolar polycentric world as the world system exits the state of bifurcation, author suggests that for Africa it is more likely that one of potential poles will fall into the zone of neocolonial interests than becoming an independent pole. Conclusion is made about the importance of cooperation between Russia and Africa, which can help the countries of Black continent to gain their identity and consolidate on basis of pan-African idea.