bluuebunny/crossref_metadata_2025_split huggingface dataset:
A mindfulness-based intervention for Substance Use Disorder in a Brazilian vulnerable population: a feasibility mixed method study
Authors: Machado Mayra Pires Alves , Opaleye Emérita Sátiro , Bedendo Andre , Bowen Sarah , Noto Ana Regina 
Published: October 2024

IntroductionSubstance Use Disorder (SUD) is a chronic condition that impacts various facets of an individual’s life, and society as a whole. The Mindfulness-Based Relapse Prevention (MBRP) protocol is an innovative intervention that can help to prevent relapse, particularly when used as a post-treatment approach. However, although there is significant evidence of its effectiveness in studies from high-income countries (HICs), there is a dearth of studies examining its feasibility and efficacy in low- and middle-income countries (LMICs). Thus, this study investigates the feasibility of MBRP as an adjunct to outpatient treatment for SUD in a socially vulnerable Brazilian population.MethodsThe study employed a mixed-methods design in eight Psychosocial Care Centers for Alcohol and Drugs (CAPS-ad) in the city of São Paulo, and involved 140 participants, 24 healthcare professionals and 7 CAPS-ad managers. In total, 17 MBRP intervention groups were conducted. The study assessed qualitative indicators of acceptability, demand, implementation, adaptation, integration, and limited efficacy testing through group interviews, in-depth interviews and field diary records. It also included limited efficacy testing of the protocol using a quantitative pre-post pilot study to investigate consumption behavior, using the Timeline Followback (TLFB) assessment method; depression, using the Center for Epidemiologic Studies Depression (CES-D) scale; anxiety, using the state trait anxiety index (STAXI-2); craving, using the Penn Alcohol Craving Scale (PACS); readiness to change, using the Readiness-to-Change Ruler (RCR); and severity of dependence, using the Severity of Dependence Scale (SDS). The qualitative data were triangulated with the quantitative data to comprehensively evaluate the feasibility of the intervention.ResultsThe sample comprised socially vulnerable participants with a high dropout rate, primarily due to social factors. Despite facing challenges in respect of regular engagement and initial cultural misperceptions of meditation, the intervention showed positive acceptance and mental health benefits, including impacts on consumption behavior.DiscussionThe study emphasizes the importance of adapting the format of the protocol to better suit vulnerable populations, and to ensure its effective integration into the public healthcare system. Future research should explore protocol modifications, assess its effectiveness in different contexts, and conduct cost-benefit analyses for broader implementation.
Frailty and suicidal ideation among older adults living alone in the community: a moderated mediation model of perceived burdensomeness and positive emotions
Authors: Yang Yang , Zhang Xinyue , Zhang Dan , Su Yonggang 
Published: October 2024

BackgroundSuicide rates among older adults individuals living alone in the community are comparatively high. The prevalence of suicidal ideation among older adults living alone in the community was assessed using the interpersonal-psychological theory of suicide and the broaden-and-build theory of positive affect.ObjectivesThe research objectives of this study was examine to the prevalence of suicidal ideation among older adults living alone in the community. It was examined whether perceived burdensomeness mediated the relation between frailty and suicidal ideation, and whether positive emotions moderated either the indirect or direct effect of a mediation model.MethodsThe model was tested on 893 older adults people living alone in the community in Xintai City, China. An assessment of participants’ frailty, suicidal ideation, perceived burdensomeness, and positive emotions was conducted.ResultsThe results demonstrated that perceived burdensomeness acted as a partly mediating factor in the relationship between frailty and suicidal ideation. In addition, the direct and indirect effects of the mediation model were moderated by positive emotions. When levels of positive emotion were high, fragility had a weaker effect on suicidal ideation, and perceived burdensomeness had a weaker effect on suicidal ideation.ConclusionResults emphasize that interventions aimed at improving positive emotions could have a protective effect on frail older people living alone in the community who are at risk of suicide.
Perceived protective behavioral changes in Chinese residents post-dynamic zero-COVID policy lifting: a cross-sectional study
Authors: Song Yuan-Yuan , Xu Ling , Liu Dan , Feng Mei , Yang Cui , Jiang Yan , Wu Ying 
Published: October 2024

ObjectiveTo investigate how Chinese residents perceived changes in their protective behaviors in the early stage after the lifting of the dynamic zero-COVID policy, and to explore the associations between the overall perceived change and factors such as demographic and health-related information, COVID-19 related perceptions, negative emotions, and coping styles.MethodsThis cross-sectional study involved 798 Chinese residents who completed an online questionnaire between 16 and 25 December 2022. The questionnaire covered demographic and health-related information, COVID-19 related perceptions, negative emotions, coping styles, and perceived changes in protective behaviors. Multiple linear stepwise regression analysis was used to determine the factors associated with the overall perceived change in protective behaviors.ResultsThe mean score for perceived protective behavioral change among participants was 61.38 (SD = 10.20), which was significantly higher than the hypothesized no-change value of 49 (p &lt; 0.001). The mean scores for each of the 15 behaviors (excluding the two vaccination-related items) were significantly greater than the hypothesized no-change value of 3 (p &lt; 0.001). The mean scores for the two vaccination-related items were significantly greater than the hypothesized no-change value of 2 (p &lt; 0.001). Among all behaviors, avoiding dining out or gathering with friends had the highest mean score (Mean = 4.16), while engaging in regular physical activity had the lowest (Mean = 3.32). Avoiding dining out or gathering with friends had the highest percentage of individuals reporting an increase (71.3%), whereas maintaining a social distance of more than 1 m had the highest percentage of individuals reporting a decrease (17.5%). Regression analysis indicated that age, worry, positive coping, female sex, negative coping, and perceived severity were associated with the overall perceived change in protective behaviors, with worry being the most predictive variable.ConclusionThis study suggested that Chinese residents perceived an increase in their protective behaviors in the early stage after the policy change, with varying magnitudes across behaviors. We identified some potentially modifiable factors associated with perceived protective behavioral change, with worry emerging as the strongest predictor, followed by positive coping, negative coping, and perceived severity. These insights offer valuable information for developing effective communication strategies, psychological support, and comprehensive models in health behavior research.
The variability of competitive performance and pacing strategies in different rounds of the 400 m and 800 m freestyle swimming races at the 2017–2024 World Swimming Championships
Authors: Fang Junhui , Li Yunpeng , Cheng Yan 
Published: October 2024

IntroductionThis study aims to analyze the competitive performance and pacing strategies (PS) of medalists and non-medalists in different rounds of the 400 m and 800 m freestyle at the World Swimming Championships.MethodThe 2017–2024 World Swimming Championships and 161 elite swimmers were selected. First, intra-athlete coefficients of variability (CVs) were evaluated using linear mixed effects modeling and changes in competitive performance (Δ); second, descriptive statistics of position lap time; finally, a computer algorithm was used to obtain PS, then a two-way ANOVA was performed.Result(i) The PS was effective in 87.5% of the swimmers in the finals compared to the heats (CVs &gt; 0.5%), but 73.8% of the males and 86.8% of the females showed an improvement in performance prior to the finals (Δ &lt; 0); (ii) Gold medalists had an average position no lower than the top 2 and established themselves in the top 3 positions more than 90% of the time, aiming to remain in the top 3 until the final 100 m if they were to win a medal; (iii) The female swimmers in 400 m were more in the heats utilize the inverted-J (race velocity change curve profile as inverted-J), men for the fast-start-even, in the final, female remain the inverted-J, men change to the U-shaped (race velocity change curve profile as U-shaped), and in the 800 m, the swimmers were unified adopt the U-shaped.DiscussionThe elite swimmers who qualified for the finals performed better in the heats and semifinals because their PS were more effective. Others, however, did not have a chance to reach the finals because their PS efficiency was lower, and their competitive performance improved less or even regressed.
Cost-consequence analysis of the enhanced recovery after surgery protocol in major lung resection with minimally invasive technique (VATS)
Authors: Buja Alessandra , De Luca Giuseppe , Dal Moro Stefano , Mammana Marco , Zanovello Anna , Miola Stefano , Boemo Deris Gianni , Storti Ilaria , Bovo Pietro , Zorzetto Fabio , Schiavon Marco , Rea Federico 
Published: October 2024

BackgroundERAS is an evidence-based multimodal perioperative protocol focused on stress reduction and promoting a return to function. The aim of this work is to perform a cost-consequence analysis for the implementation of ERAS in major lung resection by means of minimally invasive surgery (VATS) from the public health service perspective, evaluating resource consumption and clinical outcomes with respect to a control group of past patients, which did not adopt an ERAS protocol.MethodsOutcome differences (re-intervention rates, major and minor intraoperative and postoperative complications, readmissions, and mortality) as well as the costs of preoperative, operative, and postoperative care were estimated. The sample consisted of 64 consecutive patients enrolled in the ERAS programme between April 2021 and August 2022, compared to a control group (historical cohort) comprising 31 patients treated from April 2020 to December 2020, prior to the implementation of the ERAS programme. The study sample comprises patients who fulfil the established ERAS protocol inclusion criteria, including general criteria (acceptance of the protocol, proximity of residence, absence of contraindications to physiotherapy and early mobilisation), surgical criteria (anatomical lung resection up to lobectomy, absence of extensive resection, good possibility of conducting the operation in VATS) and anaesthesiologic criteria (ASA ≤2). Costs were quantified using the national health system perspective.ResultsThe average length-of-stay was at least one day shorter in the ERAS group [&lt;0.001. Average total costs including entire pathway healthcare costs were substantially reduced for ERAS-VATS patients (mean: € 5,955.71 vs. €6,529.41 Δ = −573.70 p = 0.018)]. Specifically, the median costs of the admission phase were significantly different between the two groups (median: €4,648.82 vs. €5,596.58, p = 0.008), with a reduction in hospital stay expenditure in the ERAS-VATS group (median: €1,599.62 vs. €2,399.43, p = 0.025). No significant differences were found regarding major clinical outcomes.ConclusionsThe implementation of an ERAS programme is a dominant strategy, representing an intervention capable of reducing overall costs in the context of elective anatomical lung resection with VATS without any significant differences in major complications and re-intervention rates.
Effects of a synergic interaction between magnesium sulphate and ketamine on the perioperative nociception in dogs undergoing tibial plateau leveling osteotomy: a pilot study
Authors: Galosi Margherita , Pennasilico Luca , Piccionello Angela Palumbo , Serino Federica , Tosi Francesca , Sassaroli Sara , Riccio Valentina , Angorini Alessio , Salvaggio Alberto , Di Bella Caterina 
Published: October 2024

IntroductionMagnesium Sulphate (MgSO4) is commonly used in human medicine for the management of perioperative pain in different types of procedures. However, in veterinary medicine, the use of MgSO4 has not been evaluated for its analgesic efficacy in dogs, which has generated conflicts of opinion in this area of veterinary anesthesiology. The aim of this study was to evaluate the perioperative analgesic efficacy of MgSO4 in combination with Ketamine in dogs undergoing Tibial Plateau Leveling Osteotomy (TPLO). Our hypothesis is that MgSO4 plus ketamine have a synergistic action in the management of intra-and postoperative pain.MethodsTwenty adult mixed breed dogs with average age 5.9 ± 2.6 years and weight 27.8 ± 9.2 kg were included in this prospective, clinical, randomized study. Dogs were randomly assigned to two groups. The MK group received ketamine (0.5 mg/kg as starting bolus followed by continuous infusion rate at 1 mg/kg/h). At the end of the ketamine bolus, MgSO4 (50 mg/kg over 15 min) was administered by the same route, followed by a constant rate infusion (CRI) at 15 mg/kg/h, IV. K group received a bolus of ketamine followed by a CRI at the same dosage described in MK group. Main cardiorespiratory parameters were recorded 10 min before the start of surgery (BASE), after the ketamine bolus (T1) and the MgSO4 bolus (T2), during the skin incision (SKIN), the osteotomy (OSTEOTOMY) and skin suturing (SUTURE). In the postoperative period, the short form of Glasgow Composite Pain scale (SF-CMPS) was used to assess pain at 30, 60, 120, and 180 min after extubation (Post30, Post60, Post120, and Post180, respectively). The main blood electrolytes (Mg2+, Ca2+, Na+, K+) were analyzed at BASE, T2, OSTEOTOMY, SUTURE and T3 (one hour after stopping MgSO4 infusion). Number of rescue analgesia and administration times were recorded both in the intra-and postoperative period.ResultsIn K group 7 out of 10 dogs required intraoperatory rescue analgesia compared to MK group (3/10). Furthermore, mean arterial pressure (MAP) and heart rate (HR) were significantly higher at OSTEOTOMY compared to BASE time in both groups. In the postoperative period, at T120, ICMPS-SF score was higher in K group than MK group.ConclusionThe administration of MgSO4 could guarantee better analgesia in the perioperative period in dogs undergoing TPLO, performing a synergistic action with ketamine.
Artificial intelligence-based automated determination in breast and colon cancer and distinction between atypical and typical mitosis using a cloud-based platform
Authors: Bakoglu Nilay , Cesmecioglu Emine , Sakamoto Hirotsugu , Yoshida Masao , Ohnishi Takashi , Lee Seung-Yi , Smith Lindsey , Yagi Yukako 
Published: October 2024

Artificial intelligence (AI) technology in pathology has been utilized in many areas and requires supervised machine learning. Notably, the annotations that define the ground truth for the identification of different confusing process pathologies, vary from study to study. In this study, we present our findings in the detection of invasive breast cancer for the IHC/ISH assessment system, along with the automated analysis of each tissue layer, cancer type, etc. in colorectal specimens. Additionally, models for the detection of atypical and typical mitosis in several organs were developed using existing whole-slide image (WSI) sets from other AI projects. All H&amp;E slides were scanned by different scanners with a resolution of 0.12–0.50 μm/pixel, and then uploaded to a cloud-based AI platform. Convolutional neural networks (CNN) training sets consisted of invasive carcinoma, atypical and typical mitosis, and colonic tissue elements (mucosa-epithelium, lamina propria, muscularis mucosa, submucosa, muscularis propria, subserosa, vessels, and lymph nodes). In total, 59 WSIs from 59 breast cases, 217 WSIs from 54 colon cases, and 28 WSIs from 23 different types of tumor cases with relatively higher amounts of mitosis were annotated for the training. The harmonic average of precision and sensitivity was scored as F1 by AI. The final AI models of the Breast Project showed an F1 score of 94.49% for Invasive carcinoma. The mitosis project showed F1 scores of 80.18%, 97.40%, and 97.68% for mitosis, atypical, and typical mitosis layers, respectively. Overall F1 scores for the current results of the colon project were 90.02% for invasive carcinoma, 94.81% for the submucosa layer, and 98.02% for vessels and lymph nodes. After the training and optimization of the AI models and validation of each model, external validators evaluated the results of the AI models via blind-reader tasks. The AI models developed in this study were able to identify tumor foci, distinguish in situ areas, define colonic layers, detect vessels and lymph nodes, and catch the difference between atypical and typical mitosis. All results were exported for integration into our in-house applications for breast cancer and AI model development for both whole-block and whole-slide image-based 3D imaging assessment.
The Correlation Between Mastery of Vocabulary and Reading Comprehension of the 2012/2013 Year Students at SMP Sacrojes
Authors: Xavier Marie 
Published: October 2024

This research deals with the student’s mastery of vocabulary and reading comprehension. It is aimed at finding out whether there is a high correlation between the mastery of vocabulary and reading comprehension. In this research the population was taken from the 2012/2013 year students of SMP Sacrojes. The total number of the samples was 20 students. After the data had been collected, the writer analyzed the data by using the formula of Pearson Product Moment. After calculating the correlation of mastery vocabulary and reading comprehension test, it was obtained that the correlation coefficient was 0,57. It means that there is a high correlation between mastery of vocabulary and reading comprehension. It implies that the higher the student’s mastery on vocabulary, the better they can comprehend the reading texts.
ТЕХНИКО-ЭКОНОМИЧЕСКАЯ ОЦЕНКА УСТРОЙСТВА ДЛЯ ОБРАБОТКИ ТОПЛИВА ДИЗЕЛЬНЫХ ДВИГАТЕЛЕЙ АВТОТРАКТОРНЫХ АГРЕГАТОВ ВОЛНАМИ СВЧ ДИАПАЗОНА
Authors: В.Е. Сорокин , А.Н. Бачурин , И.А. Успенский , И.А. Юхин 
Published: October 2024

Проблема и цель. Целью исследования являлась оценка технико-экономических показателей устройства для обработки дизельного топлива. Методология. Основана на определении затрат на внедрение устройства в топливную систему дизельных двигателей, проведении производственных испытаний на тракторе МТЗ-80 для сравнения изменений расхода топлива с включенным и выключенным устройством, оценена экономическая эффективность использования данного устройства. Результаты. Рассчитана удельная мощность устройства СВЧ обработки топлива для дизельного двигателя Д-243, приведена принципиальная конструкция устройства. При проведении производственных испытаний на тракторе МТЗ-80 зафиксировано среднее снижение расхода топлива на 1,18 л/ч или 6,3 % при выполнении им различных видов работ. По полученным данным топливной экономичности оценена экономическая эффективность использования данного устройства. Заключение. Показана техническая возможность использования устройства для обработки топлива волнами сверхвысокого диапазона на автотракторных агрегатах, что экономически обосновано сокращением затрат денежных средств на покупку дизельного топлива в размере 44880 руб. в год при сроке окупаемости устройства 7,5 месяцев.
Problem and purpose. The purpose of the study was to evaluate the technical and economic indicators of the device for processing diesel fuel. Methods. It is based on determining the costs of introducing the device into the fuel system of diesel engines, conducting production tests on the MTZ-80 tractor to compare fuel consumption changes with the device turned on and off, and the economic efficiency of using this device is estimated. Results. The technical feasibility of using a device for processing fuel with ultrahigh-range waves on tractor units is shown, which is economically justified by reducing the cost of funds for the purchase of diesel fuel in the amount of 44880 rubles per year with a payback period of 7.5 months for the device. Conclusion. The possibility of using a device for processing diesel fuel with microwave waves on tractor units is shown. At the same time, the cost of manufacturing and installing one device for microwave fuel treatment will amount to 23001 rubles, estimated annual savings - 44880 rubles, the payback period of the device is 7.5 months.
РАСЧЕТ ТЕПЛООБМЕННОГО АППАРАТА ДЛЯ СУБСТРАТА БИОГАЗОВОЙ УСТАНОВКИ
Authors: К.О. Оковитая , А.В. Нуждин , О.А. Суржко 
Published: October 2024

Проблема и цель. В статье изучена проблема оптимизации получения биогаза в соответствии с требованиями наилучших доступных технологий. Предложена и обоснована целесообразность использования двухстадийной биогазовой установки с теплообменным аппаратом. Проведено сравнение эффективности двух типов теплообменных аппаратов: кожухотрубного односекционного теплообменного аппарата и конструкции типа «труба в трубе». Целью работы является расчет теплообменных аппаратов биогазовой установки, предназначенной для получения биогаза из свекловичного жома. Методология. Эксплутационные параметры были установлены в ходе проектировочного расчета, основной целью которого являлось определение площади поверхности теплообмена и выбор наиболее эффективного аппарата. Результаты. На основании полученных результатов были построены графики зависимостей коэффициентов теплопередачи от скорости потока субстрата из реактора. Благодаря этим данным установлено минимальное значение площади поверхности теплообмена. Заключение. Выполненные проектировочные расчеты секционного кожухотрубного односекционного теплообменного аппарата и подогревателя типа «труба в трубе» показали возможность их использования для подогрева субстрата. Результаты расчета позволили сделать вывод, что использование в составе двухстадийной биогазовой установки с подогревателем типа «труба в трубе» более целесообразно.
Problem and purpose. The article studies the problem of optimizing the production of biogas in accordance with the requirements of the best available technologies. The feasibility of using a two-stage biogas plant with a heat exchanger is proposed and justifed. A comparison was made of the efciency of two types of heat exchangers: a shell-and-tube single-section heat exchanger and a “pipe-in-pipe” design. The purpose of the work is to calculate the heat exchangers of a biogas plant designed to produce biogas from beet pulp. Methodology. The operational parameters were established during the design calculation, the main purpose of which was to determine the heat exchange surface area and select the most efcient apparatus. Results. Based on the results obtained, graphs of the heat transfer coefcients were constructed, which showed the dependence of the linear heat transfer coefcient on the speed of the substrate. Thanks to these data, the minimum value of the heat exchange surface area was established. Conclusion. Performed design calculations of a sectional shell-and-tube single-section heat exchanger for beet pulp and a “pipe-in-pipe” heater showed the possibility of their use for heating the substrate. The calculation results allowed us to conclude that use as part of a two-stage biogas plant with a “pipe-in-pipe” heater is more appropriate.