bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of Influences of Fracture Additives on Stability of Crude Oil Emulsion
Authors: Fang Hongbo , Wang Mingxia , Liu Xiaoyun , Jin Weinan , Ma Xiangyang , Meng Xiangyu , Yan Feng 
Published: November 2018

Background:
A hydraulic fracture is a key technology to increase production of the low permeability oil fields. Fracture additives such as gels, friction reducers, pH adjusters and clay stabilizers were injected into the underground. While more than 50% of the fracture fluid remains underground. The residue of fracture fluid comes out with the produced liquid (a mixture of crude oil and water) in the subsequent oil recovery process, which results in a highly stable crude oil-water emulsion.

Objective:

The stability and stable mechanism of the emulsion with fracture fluid have been experimentally investigated.

Materials and Methods:
The influences of fracture additives and components of crude oil on the stability of emulsion were investigated by bottle test and microscopic examination. The interfacial tension and modulus of dilation were explored by a spinning drop interfacial tension meter and an interface expansion rheometer, respectively.

Results:
The fracture additives played the key role on the emulsion stability. On one hand, the interface energy of oil-water was reduced by friction reducer (IFT was decreased from 24.0 mN/m to 1.9 mN/m), which was a favor for the formation of an emulsion. On the other hand, the dilational modulus of crude oil-water film was increased by hydroxypropyl guar and pH adjuster (Na2CO3) to form a viscoelastic film, which resulted in a highly stable emulsion.

Conclusion:
The residual fracture fluid accompanied by produced liquid resulted in a highly stable emulsion. The emulsion with fracture additives was difficult to be broken, which may affect the normal production of the oil field. A positive strategy such as developing demulsifier with high efficient should be put onto the schedule.
Guided Digital Cognitive Behavioral Program for Anxiety in Primary Care: Propensity-Matched Controlled Trial
Authors: Oser Megan , Wallace Meredith L , Solano Francis , Szigethy Eva Maria 
Published: November 2018

Background
Cognitive behavioral therapy (CBT) is the gold standard treatment for adult anxiety disorders but is often not readily available in a scalable manner in many clinical settings.

Objective
This study examines the feasibility, acceptability, and effectiveness of a coach-facilitated digital cognitive behavioral program for anxious adults in primary care.

Methods
In an open trial, patients who screened positive for anxiety (General Anxiety Disorder-7 [GAD7] score ≥5) were offered the digital cognitive behavioral program (active group, n=593). Primary outcomes included anxiety, quality of life (QoL), and ambulatory medical use over 6 months. Intent-to-treat (ITT) and modified intent-to-treat (mITT) analyses were completed. Subsequently, we compared the outcomes of participants with those of a matched control group receiving primary care as usual (CAU; n=316).

Results
More than half of the patients downloaded the cognitive behavioral mobile app program and about 60% of these were considered engaged, which was defined as completion of ≥3 techniques. The active group demonstrated medium size effects on reducing anxiety symptoms (effect size d=0.44; P<.001) and improving mental health QoL (d=0.49; P<.001) and showed significantly improved physical health QoL (d=0.39; P=.002) and a decreased likelihood of high utilization of outpatient medical care (odds ratio=0.49; P<.001). The active group did not significantly outperform the CAU group in anxiety reduction or QoL improvement (d=0.20; P=.07). However, intent-to-treat analysis showed that the active group had a significantly lower likelihood of high utilization of outpatient medical care than the enhanced CAU group (P<.0001; odds ratio=0.09).

Conclusions
A coach-facilitated digital cognitive behavioral program prescribed in primary care is feasible and acceptable. Primary care patients prescribed a digital cognitive behavioral program for anxiety experienced significant improvements in anxiety symptoms, QoL, and reduced medical utilization. This effect was observed even among patients with chronic medical conditions and behavioral health comorbidities. Although the primary outcomes in the active group did not improve significantly more than the CAU group, health care utilization declined, and some secondary outcomes improved in participants who engaged in the program compared to the CAU group.

Trial Registration
ClinicalTrials.gov NCT03186872; https://clinicaltrials.gov/ct2/show/NCT03186872
Etiological Profile and Neurodevelopment Outcome of Neonatal seizure
Authors: Dongol Singh Srijana , Shrestha Ranendra Prakash Bahadur , Shrestha Asim 
Published: November 2018

IntroductionNeonatal seizures are the most common manifestation of neurological disorders in newborn period. It is an important determinant of outcome as well. This study aims to delineate the etiological profile and neurodevelopmental outcome of neonatal seizure. It is also aimed to identify the predictors of neurodevelopmental outcome in survivors.
MethodsWe recruited consecutively 117 neonates with clinically proven seizures admitted in XXXXX hospital, between February 2014 to February 2016. All of them underwent neurological diagnostic testincluding complete blood count, electrolytes, EEG, CSF analysis, neuroimaging depending upon the etiology of seizure in newborn period. After discharge, all infant with neonatal seizure underwent regular neurological examination at least 3 times within first year of life. We tested prognostic value of adverse outcome including developmental delay, post neonatal seizure, vision and hearing impairment.ResultsDuring the study period among total 954 neonates admitted in NICU and neonatal ward, 117 (12.26%) developed clinical seizures. The most common cause of neonatal seizure was hypoxic ischemic encephalopathy 69(59%), followed by infection 20 (17.09%) and metabolic disturbances collectively constituted 16(13.7%). The outcomes were mortality 16(13.7%), post neonatal seizure 18(15.4%), developmental delay 31(26.5%), vision impairment 19(16.2%) and hearing impairment 26 (22.2%).Low Apgar score at 1 minute (p=0.03), low Apgar score at 5 minute (p=0.001), early onset seizure (p<0.001), intractable seizure (p<0.001)and more than one drug used for seizure control (p=0.001) were early prognostic factors for adverse outcome.Key words: hypoxic ischemic encephalopathy, Apgar score, seizure, developmental delay
PHYTOCHEMICAL TEST OF MANGROVE Avicennia alba, Rhizopora apiculata AND Sonneratia alba FROM MUSI RIVER ESTUARY, SOUTH SUMATERA
Authors: Rahmania Nadya , Herpandi Herpandi , Rozirwan Rozirwan 
Published: November 2018

Mangrove is one of the plants that has the potential to be developed into medicinal plants. However, further research is needed to prove scientifically the content of secondary metabolites in it. This study aims to identify the secondary metabolites contained from leaves and roots in Avicennia alba, Rhizopora apiculata and Sonneratia alba. The leaves and roots of mangroves extracted by maceration using ethyl acetate. The secondary metabolites contained in mangrove samples obtained by doing phytochemical tests through color tests. Phytochemical test results showed that secondary metabolites contained in mangrove Avicennia alba are flavonoids, steroids/triterpenoids, saponins, and tannins/phenols in leaf samples, whereas in its root samples it contains flavonoids and steroids/triterponoid compounds. Sonneratia alba contains flavonoids, steroids/teriterpenoids, saponins and tannins/phenols in its leaf samples, while the root samples contain flavonoids, steroids/teriterpenoids and tannins/phenols compounds. The leaf samples of mangrove Rhizopora apiculatacontains flavonoid and steroid/triterpenoid compounds whereas in its root samples contains flavonoids, steroids/triterpenoids, saponins as well as tannins/phenols.
Factores psicosociales que intervienen en la regulación de la fecundidad en mujeres, Tunja, Colombia, 2014-2016
Authors: Robles-Santos Ruth Jael , Flórez-Escobar Isabel Cristina 
Published: November 2018

Introducción. En Colombia, la regulación de la fecundidad es un derecho, pero es necesario tener acceso a la información y a los servicios para poder decidir libremente tener hijos o no. Se presentan los factores que intervienen, entre ellos los psicosociales, para el cumplimiento terapéutico de los métodos de regulación de la fecundidad.
Objetivo. Determinar los factores psicosociales en el cumplimiento de los métodos de regulación de la fecundidad y su asociación con variables sociodemográficas.
Materiales y métodos. Se llevó a cabo un estudio descriptivo transversal con enfoque cuantitativo, con una muestra de 318 mujeres y la aplicación de una encuesta.
Resultados. El 61,6 % de las mujeres de la muestra estaba entre los 20 y los 29 años de edad; el 42,3 % obtuvo información de los métodos de regulación de la fecundidad de profesionales de la salud; el 90,0 % siempre los utilizó durante las relaciones sexuales; el 81,4 % tuvo, en promedio, dos hijos; el 19,6 % declaró haber quedado embarazadas utilizándolos; el 91,3 % expresó que es una responsabilidad compartida por la pareja, apoyándolas a seguir las indicaciones del profesional en el 66,0 %; el 56,9 % asistió siempre al control de regulación de la fecundidad. Se encontró asociación entre el nivel educativo de las mujeres y la responsabilidad en el uso de los métodos; el 97,8 % tenía educación superior y consideraba que la responsabilidad es de la pareja, y el 80,1 % de las mujeres con hijos acudía siempre a los controles.
Conclusiones. Los factores psicosociales inciden en el cumplimiento de los métodos de regulación de la fecundidad, dado que un porcentaje significativo refirió como estado conyugal la unión libre, lo que les permitía autonomía para la elección del método y apoyo de la pareja. Las mujeres participaron voluntariamente en el programa y hubo satisfacción con la atención y con la información brindada por el proveedor del servicio.
Percepción de la calidad de la atención en un servicio de urgencias
Authors: Cobo-Mejía Elisa Andrea , Gómez-Martínez Flor Edilia , Rodríguez-Leal María Yohana 
Published: November 2018

Introducción. El reconocimiento de la percepción del usuario de la calidad del servicio de urgencias mediante el modelo evaluativo Service Performance, permite la orientación de acciones para mejorar los servicios prestados.
Objetivo. Determinar la percepción de la calidad de la atención del servicio de urgencias de una Empresa Social del Estado en Boyacá.
Método. Se hizo una investigación descriptiva de diseño transversal, con una muestra conformada por 108 usuarios que recibieron atención en el servicio de urgencias durante el segundo semestre del año 2017. Para la recolección de la información, se utilizó la encuesta Service Performance, la cual consta de 22 preguntas organizadas en cinco dimensiones que permiten evaluar la calidad del servicio según la percepción del usuario.
Resultados. La percepción de los usuarios sobre la calidad del servicio de urgencias, en cada una de las cinco dimensiones, obtuvo un puntaje promedio general de 4,09, siendo la dimensión de seguridad la más alta, con un promedio de 4,23, seguida de la empatía, con 4,18, la de capacidad de respuesta, con 4,14, la de fiabilidad, con 4,09 y, la más baja, los elementos tangibles, con 3,79.
Conclusiones. El conocer la percepción de la calidad del servicio de urgencias permite desarrollar acciones, establecer confianza y hacer el seguimiento de la calidad del servicio.
Medical exchange project for students and young doctors between Japan and Russia
Authors: Yamakawa S. , Razvina O. , Ito M. , Hibino H. , Someya T. , Ushiki T. 
Published: November 2018

Abstract
For more than 25 years Niigata University School of Medicine has been organizing medical exchanges with universities of the Russian Far East and Siberia. This exchange has turned out to be mutually beneficial for both universities, giving motivation to medical students and young doctors to strive for knowledge of international medicine. “Program for priority placement of foreign students sponsored by Japanese government” and “Re-inventing Japan project” initiated by Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) were adopted in 2014, so it gave us a perfect opportunity to expand the existing program. In 2017, the MEXT approved the application of Niigata University together with Hokkaido University for «Program of Globalization in the field of university education (in cooperation with Russia), the creation of a platform for interaction”. We hope advances in the field of medicine and medical care achieved as a result of such unique cooperation between Japan and Russia will greatly contribute not only to the welfare of citizens of both countries, but also to the development of industry and economy. We would like to share experience gained by our university in the sphere of Japanese-Russian medical exchanges and educational programs, as well to describe the prospects for further development.
Renoprotective potential of quercetin in experimental diabetic nephropathy: assesing antiapoptotic and antioxidant effects
Authors: TUNÇDEMİR Matem , BÜYÜKÇOLPAN MİRZATAŞ Eda , UZUN Hafize 
Published: November 2018

Aim: We investigated renoprotective
and anti-apoptotic effects of quercetin, a potent bioflavonoid, by evaluating expression
of apoptosis-regulatory genes that contribute to the kidney damage caused by
diabetes in rats.

Methods: Rats were divided
into 4 groups; Control, STZ-induced diabetic, STZ-induced diabetic+Quercetin
and Quercetin control. Values of fasting blood glucose, body weight and urine
microalbuminuria measured. Immunohistochemistry was performed using bax, bcl-2,
caspase-3 antibodies. For apoptosis detection, TUNEL method was applied.
Advanced oxidation protein products (AOPP), protein carbonyl oxidation (PCO),
malondialdehyde (MDA) and superoxide dismutase (SOD) activity were measured in
homogenized kidney tissues.

Results: Blood glucose and
microalbuminuria levels were significantly decreased in quercetin-treated
diabetic group compared to the untreated-diabetic group (p=0.020 and p=0.003; respectively). MDA, AOPP and PCO levels were significantly
decreased (p=0.001, p=0.0001 and p=0.0005; respectively); however, SOD activity
were found to increase in quercetin-treated diabetic group (p=0.005).
Immunostaining of bcl-2, bax and caspase-3 was decreased compared to the
untreated-diabetic group. Apoptotic cells especially increased in the kidney
tubuli of untreated-diabetic group and on the contrary, a significant decrease
was observed in the group that received a quercetin treatment (p=0.0001).

Conclusion:
Our results revealed that antiapoptotic effects of quercetin, which has predominantly
antioxidant effects, may be useful in reducing effects of diabetic
complications and preventing new complications.
A rare presentation of anthrax with sepsis: A case report
Authors: DÜLGER Mahmut , MURAT Kenan 
Published: November 2018

Anthrax is a zoonotic infection caused by Bacillus anthracis. Although the incidence of the disease is decreasing in our country, it is still endemic in certain regions of the country. The cutaneous form of the disease is the most common clinical form, which is usually benign and rarely causes bacteriemia and sepsis. In this case report, a cutaneous anthrax case who had positive blood and wound cultures and were complicated with sepsis are presented. A 39-years-old male patient living in Kars (Eastern Turkey) was admitted with systemic fever, chills,and a wound with swelling redness on the right arm. In his medical history, the patient stated an insect (fly) bite three days ago and consequent development of a lesion on his right arm. He also stated that he had slaughtered a lamb 10 days ago by himself. On admission, the patient was detected to have a 2-3 cm centrally necrotic and peripherally edematous wound confined to the right forehand. There was also fever, hyperemia and general edema confined to right arm up to the shoulder level. With the preliminary diagnosis of cutaneous anthrax, the patient was hospitalized, and ampicillin-sulbactam therapy was started, but due to the progression of the lesion and clinical deterioration, the treatment was changed to piperacillin-tazobactam and clindamycin. The swab samples from the wound were sent to the laboratory and revealed Gram-positive sporulated bacilli and following blood cultures were also positive for growth. The agent pathogen was identified as B.anthracis by Gram stains from wound samples and blood cultures which was susceptible to penicillin. MLVA method with 25 loci was used for genotyping, and it was determined that the genotype in our case is GK43 that is located in the major cluster A and subset 3. On the tenth day of hospitalization due to the widespread and necrotic lesions on his arm , compartment syndrome had been occurred. Escharatomy had been established for the treatment of comparment syndrome. After three weeks of antibiotherapy, the patient has been discharged from the hospital with good health.As a conclusion, this case report reminds need of
high attention to the clinical course of
cutaneous anthrax in order to avoid severe complications such as sepsis.
EFFECT OF PROFITABILITY, INVESTMENT DECISION ON COMPANY VALUE IN MANUFACTURING COMPANY LISTED IN INDONESIA STOCK EXCHANGE
Authors: Setiyorini Ayu Karnulis , Kartika Chandra 
Published: November 2018

Penelitian ini bertujuan untuk menguji pengaruh profitabilitas dan keputusan investasi terhadap nilai perusahaan. Return On Asset (ROA) digunakan sebagai proksi profitabilitas, Total Asset Growth (TAG) sebagai proksi keputusan investasi, dan Price Book Value (PBV) sebagai proksi nilai perusahaan. Metode pengambilan sampel menggunakan metode purposive sampling, yaitu menggunakan sampel dengan pertimbangan – pertimbangan tertentu , perusahaan yang terdaftar dalam Bursa Efek Indonesia selama periode 2017 – 2018. Sampel yang digunakan adalah 4 perusahaan yang terdaftar dalam Bursa Efek Indonesia. Metode analisis yang digunakan trianggulasi yaitu analisis regresi linier berganda. Hasil penelitian ini secara parsial menunjukkan bahwa profitabilitas (ROA) dan keputusan investasi (TAG) berpengaruh positif dan signifikan terhadap nilai perusahaan (PBV). Secara simultan, kedua variabel independen tersebut mempengaruhi variabel nilai perusahaan (PBV), namun nilai perusahaan tidak hanya dipengaruhi oleh social-faktor internal, nilai perusahaan juga dipengaruhi oleh social eksternal seperti tingkat suku bunga, tingkat inflasi, kurs mata uang dan situasi social politik.Kata Kunci: Nilai perusahaan (PBV), profitabilitas (ROA), keputusan investasi (TAG).
EARNINGS PER SHARE AND EARNINGS PER SHARE AND STOCK REMEDIES ON STOCK FINANCIAL RESPONSIBILITY COMPANY LISTED IN INDONESIA STOCK EXCHANGE DATE 31 MARCH 2017 FOR THE PERIOD 3 (THREE) MONTHS
Authors: Lestari Qurnia Putri , Kartika Chandra 
Published: November 2018

Penelitian ini bertujuan untuk menguji pengaruh earnings per share dan manajemen laba terhadap return saham pada perusahaan jasa keuangan milik BUMN yang terdaftar dibursa efek Indonesia pada tanggal 31 Maret 2017 untuk periode 3 (tiga) bulan. Metode pengambilan sampel menggunakan metode purposive sampling, yaitu menggunakan sampel dengan pertimbangan – pertimbangan tertentu , perusahaan jasa keuangan yang menerbitkan laporan keuangan pada tanggal 31 maret untuk periode 3 (tiga) bulan. Sampel yang digunakan adalah 4 perusahaan jasa keuangan milik BUMN. Metode analisis yang digunakan yaitu analisis regresi linier berganda. Hasil hipotesis 1, secara simultan EPS dan Manajemen Laba berpengaruh signifikan terhadap Return Saham. Hipotesis 2 & 3 , Penelitian ini menghasilkan secara empiris, berlawanan secara parsial tidak berpengaruh yang signifikan dari Manajemen Laba dan EPS terhadap Return saham.Kata Kunci: Earnings Per Share, Manajemen laba, Return saham
Cadre Deployment Policy and its Effects on Performance Management in South African Local Government: A Critical Review
Authors: Shava Elvin , Chamisa Shingirayi Florence 
Published: November 2018

The change from a politically-sanctioned racial segregation opened support of another popularity based administration which was an overwhelming procedure at all levels. In South Africa, the positive policies to turnaround the economy of the country came along with cadre deployment policy which advocates for ANC party loyalists to occupy a prominent position in the public sector. This political patronage via state jobs leads to poor institutional quality or performance of the nation as a whole. Focusing on the significant association between the demands of economic growth and expansion, this paper assesses the effects of the cadre deployment policy against performance management in the public sector. It presents a proposed framework based on the control theories illustrating how cadre deployment and performance management can contribute to the current knowledge of the African academic and administrative environment. The article adopted an extensive review of literature which was premised on various document sources that inform cadre deployment, Auditor General Reports, Annual Reports and relevant literature on the subject. Results of this study showed that cadre deployment exacerbated corruption, poor procurement systems and wasteful expenditure and the deteriorating State of Local Government. Â The article calls for the review and the changes of the authoritative structure governing local municipalities in order to supplement Section (152) of the Constitution of the Republic of South Africa. The article further directs the ANC led government to revise the cadre deployment policy to combat the challenges of severe skills shortage and poor service delivery in various municipalities across the country as a result of nepotism, politicization and hiring unqualified labour.
Elderly Fathers in Russia after Divorce: Gender Differences in the Intergenerational Transfers
Authors: Tretyakova Ekaterina 
Published: November 2018

Regarding the aging population, the question of care and financial support of the elderly becomes increasingly relevant. At the same time, the rise of divorce and separation becomes a very strong trend in modern society. Due to the absence of joint custody in Russia, the connection between fathers and children weakens after divorce and in this context the research question is: Do children help their elderly fathers after divorce, and what is the gender specificity in upward transfers after divorce? The object of this study is to examine the transfers that elderly Russian men and women receive from their children. This research is based on data from the “Comprehensive Monitoring of Living Conditions of the Population” conducted in Russia in 2014. The target sample consisted of 113 000 persons over 15 years old—37 787 of which were over retirement age. The survey covered all regions of the Russian Federation. The method used in this analysis is mainly descriptive statistics and correlation tables. According to the results there is a considerable gap between elderly men and women in getting help from their children due to weakened connections between children and their fathers after divorce. This problem can be solved by developing institutions of social protection, but unfortunately such institutions in Russia have not yet been sufficiently developed.
No exterior do cubo branco
Authors: Melo Havane 
Published: November 2018

O trabalho é um retorno das reflexões geradas pelo livro No Interior Do Cubo Branco: a ideologia do espaço da arte, de Brian O'Doherty (Martins Fontes, 2002). Provocados pelo autor, usamos de ironia para questionar se, de fato, podemos pensar fora de cubos e caixas ou se tudo não passa de um eterno retorno a essa forma geométrica básica, mesmo em meio ao caos e a bagunça.