bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sulfur, Nitrogen Dual Doped Reduced Graphene Oxide Supported Two‐Dimensional Sb2S3 Nanostructures for the Anode Material of Sodium‐Ion Battery
Authors: Bag Sourav , Roy Amlan , Mitra Sagar 
Published: June 2019

AbstractDeveloping alternative of Li‐based energy storage system are inevitable and demanding because of depleting Li source and increasing cost. In this aspect Na‐based electrochemical energy storage devices such as Na‐ion batteries has drawn significant attention due to ubiquity, low cost and less toxic nature. Development of electrode material with novel architecture and high specific capacity is important and challenging too. Herein, we have demonstrated a novel two‐dimensional nanostructured hybrid anode material based on Sb2S3 and, sulfur and nitrogen dual doped reduced graphene oxide for Na‐ion battery. Hybrid material was synthesized by solvothermal process. X‐ray diffraction pattern, Raman and FTIR spectral, and microscopic measurements exhibits successful synthesis of crystalline and two‐dimensional layered structure material. The hybrid material shows excellent properties towards Na+ storage properties. A specific capacity of 507 mA h g−1 at a current density of 100 mA g−1 was also obtained after continuous 150 charge‐discharge cycles. The specific capacity, and electrochemical properties of hybrid material over performs free‐Sb2S3. The excellent electrochemical properties of the hybrid material are attributed to easy ion diffusion through the two‐dimensional layered structure.
Ball Milling Modified SAPO‐11 Based Catalysts for n‐Decane Hydroisomerization
Authors: Ferreira Luisa , Ribeiro Filipa , Fernandes Auguste , Martins Angela 
Published: June 2019

AbstractBifunctional Pt/SAPO‐11 catalysts were prepared using as acid matrix the microporous silico‐aluminophosphate, SAPO‐11, synthesized under microwave radiation. After synthesis, the material was physically modified using a ball mill, changing the grinding time but keeping frequency constant. The metal function (0.5 wt.% Pt) was introduced through mechanical mixture with commercial Pt loaded alumina. The catalysts were characterized by several techniques: powder X‐Ray Diffraction, pyridine adsorption followed by infrared spectroscopy, low temperature N2 adsorption, Hg intrusion porosimetry and electronic microscopy (SEM). The characterization data show modifications of structural and textural properties of the samples as the milling time increases. The catalytic behaviour of Pt/SAPO‐11 materials was studied for hydroisomerization of long chain n‐alkanes, using n‐decane as model molecule, aiming to increase the production of mono‐branched isomers. The catalytic results show that, under optimized milling conditions (60 min; 50 Hz) the selectivity into mono‐branched isomers increased when compared with parent catalyst.
Mito‐docking: A Novel In Vivo Method to Detect Protein–Protein Interactions
Authors: Shao Wei , He Lihong , Deng Fei , Wang Hualin , Vlak Just M. , Hu Zhihong , Wang Manli 
Published: June 2019

AbstractMany methods have been developed to detect protein–protein interactions (PPIs) and explore cellular processes. However, effective methods for detecting complicated PPIs under physical conditions are still in demand. Here, a simple and efficient mitochondria‐docking (Mito‐docking) method for PPI detection in vivo is developed. The strategy is to anchor a “bait” protein to mitochondrial outer membrane (MOM), and then trap the “prey” protein onto MOM. In this way, interacting signals are enriched to allow easy detection. This method efficiently detects the well‐known interaction between two G protein subunits (Gγ2 with Gβ1) and is successfully applied to investigate the recognition of importin α superfamily members for the classical nuclear localization signal (NLS) of simian virus 40 (SV40) large T antigen, which are highly dynamic and not easily visualized by conventional methods. As far as is known, this is the first time that the interaction between human importin α receptors with NLSs has been visualized. The results prove that Mito‐docking can be used as a simple, straightforward, and intuitive method to study PPIs qualitatively and quantitatively in vivo.
Phylogenetic relationships of the Early Miocene diving and flightless duck Cayaoa bruneti (Aves, Anatidae) from Patagonia: homology or convergence?
Authors: De Mendoza Ricardo S. 
Published: June 2019

AbstractCayaoa bruneti, from the early Miocene Gaiman Formation of Chubut, Argentina, provides the earliest evidence for diving behaviour and the earliest example of flight loss within Anseriformes. It is also the only known diving duck from South America. A new phylogenetic analysis using only morphological characters places Cayaoa bruneti as part of a single radiation of diving ducks within Anatinae, as sister group to the Erismaturinae. Partition analysis of subsets of characters shows that the humerus and femur have the strongest effect in generating this phylogeny, while the skull characters result in groupings closer to those seen in analyses with molecular data. When the analysis is constrained by enforcing the molecular tree as a backbone, Cayaoa bruneti emerges as a basal branch within the Erismaturinae. These results make Cayaoa bruneti an independent and early example of the recurring evolution of flightlessness in large marine Anatidae.
Recent Progress and Emerging Applications of Rare Earth Doped Phosphor Materials for Dye‐Sensitized and Perovskite Solar Cells: A Review
Authors: Rajeswari Ramireddy , Islavath Nanaji , Raghavender M. , Giribabu Lingamallu 
Published: June 2019

AbstractAlthough the efficiency of Dye‐sensitized and Perovskite solar cell is still below the performance level of market dominance silicon solar cells, in last few years they have grabbed significant attention because of their fabrication ease using low‐cost materials, and henceforth these cells are considered as a promising alternative to commercial photovoltaic devices. However, third generation solar cells have significant absorption in the visible region of solar spectrum, which confines their power conversion efficiency. Subsequently, the performance of current photovoltaics is significantly hampered by the transmission loss of sub‐band‐gap photons. To overcome these issues, rare earth doped luminescent materials is the favorable route followed to convert these transmitted sub‐band‐gap photons into above‐band‐gap light, where solar cells typically have significant light‐scattering effects. Moreover, the rare earth based down/up conversion material facilitates the improvement in sensitization, light‐scattering and device stability of these devices. This review provides insight into the application of various down/up conversion materials for Dye‐sensitized and perovskite solar cell applications. Additionally, the paper discusses the techniques to improve the photovoltaic performance in terms of current density and photo voltage in detail.
Geraniin inhibits oral cancer cell migration by suppressing matrix metalloproteinase‐2 activation through the FAK/Src and ERK pathways
Authors: Yeh Chia‐Ming , Hsieh Ming‐Ju , Yang Jia‐Sin , Yang Shun‐Fa , Chuang Yi‐Ting , Su Shih‐Chi , Liang Meng‐Yuan , Chen Mu‐Kuan , Lin Chiao‐Wen 
Published: June 2019

AbstractGeraniin has been reported to have numerous biological activities, including antiviral, antihypertensive, antihyperglycaemic, liver protective, antidiabetic, and apoptotic activities. However, the anti‐migration effects of geraniin on oral cancer remain elusive. In this study, we revealed the potential antitumor mechanisms of geraniin through the inhibition of the migration and invasion of human oral cancer cell lines SCC‐9 and SCC‐14. The results of gelatin zymography and Western blot assays revealed that geraniin significantly reduced the activity and expression of matrix metalloproteinase‐2 (MMP‐2) of oral cancer cells in a concentration‐dependent manner. Furthermore, geraniin potently suppressed the phosphorylation of focal adhesion kinase (FAK), Src, and extracellular signal‐regulated kinase (ERK)1/2 but did not affect the phosphorylation of p38 mitogen‐activated protein kinase (MAPK) and c‐Jun N‐terminal kinase 1/2. Moreover, blocking the MAPK/ERK1/2 pathway significantly enhanced the anti‐migration ability of geraniin in oral cancer cells. In conclusion, we demonstrated that geraniin inhibits the motility of SCC‐9 and SCC‐14 cells in vitro through a molecular mechanism that involves the attenuation of MMP‐2 expression and activity mediated by decreased FAK/Src and ERK1/2 pathways.
Return to Sport and Sports-Specific Outcomes following Ulnar Collateral Ligament Reconstruction in Adolescent Athletes: A Systematic Review
Authors: Glogovac Georgina , Kakazu Rafael , Aretakis Alexander Constantine , Grawe Brian M. 
Published: June 2019

Background The incidence of elbow injuries and ulnar collateral ligament (UCL) reconstruction in adolescent athletes is increasing. Knowledge and expectations of outcomes following this procedure are necessary for proper counseling and decision-making in this age group. Questions/Purposes We sought to report patient-reported outcomes, rate of return to sport, and rate of complications and reoperation following UCL reconstruction in adolescent athletes. Methods A systematic review was conducted for adolescent athletes undergoing UCL reconstruction. The primary outcome measure was patient-reported outcome scores, specifically the Conway Scale, the Andrews-Timmerman score, and the Kerlan-Jobe Orthopaedic Clinic (KJOC) score. Secondary outcome measures included return to sport, rate of subsequent procedures, and complication rate. A descriptive analysis was performed. Results Seven studies met the inclusion criteria. The average patient-reported outcome scores ranged from 81 to 87% (Conway, “excellent”), 83.6 to 92.7 (Andrews-Timmerman), and 76 to 89.3 (KJOC). The average rates of return to sport were 84% to preinjury level or higher, 93% to any level, and 57% to a higher level. Complication rates ranged from 0.7 to 11%. Rate of subsequent elbow procedures ranged from 0 to 10%. Conclusions This systematic review demonstrates favorable outcomes in adolescent athletes following UCL reconstruction. Patient-reported outcome scores and rates of return to sport were comparable with those reported in adult athletes. The procedure is not without risk of complications, and patients and parents should be counseled regarding this risk prior to surgery.
Characterization and functional analysis of pollen-specific PwSWEET1 in Picea wilsonii
Authors: Zhou Yanni , Cui Xiaoyue , Hu Anni , Miao Yahui , Zhang Lingyun 
Published: June 2019

AbstractSWEET transporters play a pivotal role in sugar transport in plants. However, their functions in pollen tube growth, especially in coniferous species remain unknown. Here, we used RT-qPCR to reveal that a SWEET1 gene was specifically expressed in pollen and pollen tubes of Picea wilsonii. A pollen germination assay showed that PwSWEET1 was induced by H3BO3 but not by Ca2+. In a sugar specificity experiment, sucrose (Suc) and glucose (Glc) were effective sugars for pollen germination and pollen tube growth. PwSWEET1 expression was induced most by Suc and Glc. Heterologous expression of PwSWEET1 in yeast showed that PwSWEET1 can restore the glucose absorption in yeast strain EBY.VW4000, which has a hexose absorption defect, and the absorption of glucose is pH-independent. This evidence supports the involvment of PwSWEET1 in boron-dependent glucose transport in pollen germination and pollen tube growth of Picea wilsonii.
H3K27me3 Signal in the Cis Regulatory Elements Reveals the Differentiation Potential of Progenitors during Drosophila Neuroglial Development
Authors: Chen Xiaolong , Ye Youqiong , Gu Liang , Sun Jin , Du Yanhua , Liu Wen-Ju , Li Wei , Zhang Xiaobai , Jiang Cizhong 
Published: June 2019

Abstract
Drosophila neural development undergoes extensive chromatin remodeling and precise epigenetic regulation. However, the roles of chromatin remodeling in establishment and maintenance of cell identity during cell fate transition remain enigmatic. Here, we compared the changes in gene expression, as well as the dynamics of nucleosome positioning and key histone modifications between the four major neural cell types during Drosophila neural development. We find that the neural progenitors can be separated from the terminally differentiated cells based on their gene expression profiles, whereas nucleosome distribution in the flanking regions of transcription start sites fails to identify the relationships between the progenitors and the differentiated cells. H3K27me3 signal in promoters and enhancers can not only distinguish the progenitors from the differentiated cells but also identify the differentiation path of the neural stem cells (NSCs) to the intermediate progenitor cells to the glial cells. In contrast, H3K9ac signal fails to identify the differentiation path, although it activates distinct sets of genes with neuron-specific and glia-related functions during the differentiation of the NSCs into neurons and glia, respectively. Together, our study provides novel insights into the crucial roles of chromatin remodeling in determining cell type during Drosophila neural development.
Applying behavioural insights to child protection: venturing beyond the low-hanging fruit
Authors: BOLTON ANNALESE , NEWELL BEN R. , GANDEVIA SIMON , PEEK JAMES , BERROCAL CAPDEVILA ELENA 
Published: June 2019

AbstractWe explore whether simple behavioural insights techniques can be successful for addressing a policy issue within one of society's more complex and difficult sectors: child protection. Child protection reporting practices in New South Wales, Australia, reveal that the public's primary response is to report to the statutory authority, who only deal with cases of the highest risk. As a result, a large volume of statutory resources are spent processing lower-risk reports that lead to no benefits for lower-risk families and slow down response times for families that require a statutory response most. Our goal was to reduce lower-risk reporting by encouraging alternative responses to these situations. To do this, we altered report feedback for cases deemed lower risk in order to make alternative responses more salient and we added a persuasive message framed as a gain or loss. We then examined subsequent reporting accuracy. We found that our trial was linked to a modest improvement in reporting accuracy, though the results may have been diluted by a spill-over effect. We discuss how facilitating a greater behavioural change likely requires multi-organization collaborations, extending the range of insights drawn from behavioural science and/or addressing issues from multiple angles.
Efficacy of intervention at traffic schools reducing impulsive action, and association with candidate gene variants
Authors: Luht Kadi , Tokko Tõnis , Eensoo Diva , Vaht Mariliis , Harro Jaanus 
Published: June 2019

AbstractObjectiveRoad traffic injuries are the leading cause of death among young people. Recognition of the contribution of impulsive behaviour may help novice drivers to behave more safely. Previously a brief intervention focusing on impulsive traffic behaviour conducted by psychologists in driving schools had been effective. The aim of this study was an independent re-evaluation of the effect of the intervention, as conducted by driving school teachers, and assessment of the potential associations with candidate genotypes.MethodsDriving school students (mean age 22.5, SD=7.9) were divided into intervention (n=704) and control (n=737) groups. Driving school teachers were trained to administer the intervention which consisted of a lecture and group work (1.5 h in total) on impulsivity. Traffic offences and crashes were monitored during 3 years, using police and traffic insurance fund databases. Functional polymorphisms of the dopamine transporter (DAT) and serotonin transporter genes (DAT1VNTR and 5-HTTLPR) were assessed.ResultsThe intervention significantly lowered general traffic risk and prevalence of traffic accidents.DAT1VNTR 9R carriers, particularly males, had higher general traffic risk in the whole sample. Female 5-HTTLPR s’ allele carriers of the intervention group had the lowest general traffic risk. Intervention was most effective in femaleDAT1VNTR 10R/10R homozygotes.ConclusionsBrief impulsivity-centred intervention appears as a promising strategy for preventing risk-taking behaviour in novice drivers and can be fully integrated to driving school curriculum.
Effects of prophylactic administration of glutamine on CD4+T cell polarisation and kidney injury in mice with polymicrobial sepsis
Authors: Hou Yu-Chen , Wu Jin-Ming , Chen Kuen-Yuan , Chen Po-Da , Lei Cing-Syuan , Yeh Sung-Ling , Lin Ming-Tsan 
Published: June 2019

AbstractThe present study investigated the effects of glutamine (GLN) pretreatment on CD4+T cell polarisation and remote kidney injury in mice with gut-derived polymicrobial sepsis. Mice were randomly assigned to three groups: normal control fed with American Institute of Nutrition (AIN)-93G diet and two sepsis groups provided with either AIN-93G-based diet or identical components, except part of casein was replaced by GLN. Mice were given their respective diets for 2 weeks. Then, mice in the sepsis groups were performed with caecal ligation and puncture and were killed 72 h after the surgery. Blood, spleens and kidneys were collected for further examination. The results showed that sepsis resulted in decreased circulating and splenic total T lymphocyte and CD4+T cell percentages, whereas IL-4-, and forkhead box p3 (Foxp3)-expressing CD4+T cells percentages were up-regulated. Compared with the sepsis control group, pretreatment with GLN maintained blood T and CD4+T cells and reduced percentages of IL-4- and Foxp3-expressing CD4+T cells. Also, a more pronounced activation and increased anti-apoptotic Bcl-2 gene expression of splenic CD4+T cells were observed. Concomitant with the decreased plasma IL-6, keratinocyte-derived chemokine (KC) levels, the gene expression of KC, macrophage inflammatory protein-2 and renal injury biomarker kidney injury molecule-1 (Kim-1) were down-regulated when GLN was administered. These findings suggest that antecedent of GLN administration elicit a more balanced blood T helper cell polarisation, sustained T cell populations, prevented splenic CD4+T cell apoptosis and attenuated kidney injury at late phase of polymicrobial sepsis. GLN may have benefits in subjects at risk of abdominal infection.
Does food insulin index in the context of mixed meals affect postprandial metabolic responses and appetite in obese adolescents with insulin resistance? A randomised cross-over trial
Authors: Caferoglu Z. , Hatipoglu N. , Gokmen Ozel H. 
Published: June 2019

AbstractThe food insulin index (II) is a novel classification to rank foods based on their physiological insulin demand relative to an isoenergetic reference food and may be a valid predictor of postprandial insulin responses and appetite. The present study aimed to compare the postprandial metabolic responses and appetite sensations to two macronutrient- and glycaemic index-matched meals with either high or low II in obese adolescents with insulin resistance (IR). A randomised, single-blind and cross-over trial included fifteen obese adolescents aged 12–18 years with IR. All participants were provided with two different breakfasts: low glycaemic index, low insulin index (LGI-LII) and low glycaemic index, high insulin index (LGI-HII), with a 1-week washout period between meals. At time 0 (just before breakfast), 15, 30, 45, 60, 90, 120, 180 and 240 min after the meal, serum glucose, insulin and C-peptide levels and appetite scores were measured. At the end of 4 h, participants were served ad libitum lunch. Early (0–30 min), late (45–240 min) and total (0–240 min) postprandial insulin responses were lowered by 56·1, 34·6 and 35·6 % after the LGI-LII meal v. LGI-HII meal (P < 0·05). The feeling of hunger was also decreased by 25·8 and 27·5 % after the LGI-LII meal v. LGI-HII meal during the late and total responses (P < 0·05). The calculation II of meals or diets may be a useful dietary approach to reduce postprandial hyperinsulinaemia and the perceived hunger in obese adolescents with IR.
Expenditure in Life Assurance Offices
Authors: Harding H. R. , Strachan T. Y. 
Published: June 2019

A paper bearing the title “Life Offices:—in reference to Expenses, New Business, Profit divided, and Competition”, was read before the Institute at its Ordinary Sessional Meeting on 25 March last, and was followed by a discussion, of which a summary is appended hereto.From the nature of the subject it was necessary that the author should quote from the Board of Trade Returns of the various life offices, and these quotations being in such a form as to enable anyone versed in the business of life insurance to identify in various instances the companies to which they related, it was considered by the Council of the Institute desirable that, acting in conformity with its practice not to give countenance to criticisms upon the affairs of individual life offices, only an abstract of the leading features of the paper should be given instead of printing the paper and tables in extenso.
The effect of Xenopus laevis egg extracts with/without BRG1 on the development of preimplantation cloned mouse embryos
Authors: Chiang Chien-Yueh , Chen Xin-Yu , Lin Chun-Ting , Tang Pin-Chi 
Published: June 2019

SummaryMuch effort has been devoted to improving the efficiency of animal cloning. The aim of this study was to investigate the effect of BRG1 contained in Xenopus egg extracts on the development of cloned mouse embryos. The results showed that mouse NIH/3T3 cells were able to express pluripotent genes after treatment with egg extracts, indicating that the egg extracts contained reprogramming factors. After co-injection of Xenopus egg extracts and single mouse cumulus cells into enucleated mouse oocytes, statistically higher pronucleus formation and development rates were observed in the egg Extract− co-injected group compared with those in the no egg extract-injected (NT) group (38–66% vs 18–34%, P<0.001). Removal of BRG1 protein from Xenopus egg extracts was conducted, and the BRG1-depleted extracts were co-injected with single donor cells into recipient oocytes. The results showed that the percentages of pronucleus formation were significantly higher in both BRG1-depleted and BRG1-intact groups than that in the nuclear transfer (NT) group (94, 64% vs 50%, P<0.05). Furthermore, percentages in the BRG1-depleted group were even higher than in the BRG1-intact group (94% vs 64%). More confined expression of Oct4 in the inner cell mass (ICM) was observed in the blastocyst derived from the egg extract-injected groups. However, Nanog expression was more contracted in the ICM of cloned blastocysts in the BRG1-depleted group than in the BGR1-intact group. Based on the present study, BRG1 might not play an essential role in reprogramming, but the factors enhancing pronucleus formation and development of cloned mouse embryos are contained in Xenopus egg extracts.