bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pilot training for clinical research professionals in using empathy to recognize and respond to implicit bias in research recruitment and retention
Authors: Adams Jennifer , Gonzalez Cristina M. , Gillespie Colleen , Holahan James , Minsky Maura , Datta Suchismita , Medina Rosario , Yakubov Amin , Byrnes Kimberly , Bredella Miriam A. 
Published: November 2024

Abstract
Recruiting and retaining research participants is challenging because it often requires overcoming structural barriers and addressing how histories of mistrust and individuals’ lived experiences affect their research engagement. We describe a pilot workshop designed to educate clinical research professionals on using empathy skills to recognize and mitigate bias to improve recruitment and retention. In a post-workshop survey (22/31 participants completed), 94% agreed the workshop helped them practice perspective-taking, recognize implicit bias, and identify opportunities for empathy. Participants reported increased confidence in key recruitment and retention skills (p < 0.05). Future studies will evaluate whether this translates into improved recruitment.
A review of reported stakeholder engagement in early-stage translational research
Authors: Concannon Thomas W. , Hughes Marguerite Fenwood , LaVertu Amy E. , Garlick Jonathan , Rushforth Alice M. 
Published: November 2024

Abstract

Background:
We conducted a scoping review of peer-reviewed literature to describe the nature and extent of reporting on the involvement of stakeholders in early-stage translational research.

Methods and results:
We conducted two literature searches in six databases, screened records and full-text articles, and abstracted and analyzed data from included publications. The literature searches yielded unduplicated 2,894 records. After screening, 13 articles were included.

Findings:
Our review of the literature yielded rare reports of engagement in early-stage translational research. Half of included articles reported on engagement with patients, clinicians, and researchers while fewer that one in three reported on engagement with policymakers, industry, and insurers. One in four reported engagement in the publication’s acknowledgments but not in the main text. More than half drew unmeasured conclusions about the outcomes of engagement.

Interpretation:
Our definition of early-stage translation pointed to a specific set of peer-reviewed research; our findings indicate a reporting gap and not necessarily a gap in practice. By addressing four themes–developing a shared language, identifying frameworks and principles, creating a repository of resources, and establishing a research agenda, research leaders can develop new insights about how to engage communities in early-stage translational research.
Calabresi’s invite: bridging Law & Society and Law & Economics through “situated valuation”
Authors: Tejani Riaz 
Published: November 2024

AbstractLaw & Society scholars often dismiss Law & Economics (L&E) as insoluble with our core beliefs about distributive justice, culture, and social solidarity. This reaction has yielded missed opportunities for new theory emergent between the fields. One such opportunity came in 1978, when Guido Calabresi and Philip Bobbitt argued that societies make “tragic choices” about scarce resource allocations so as to reconcile such choices with core culture, ethics, and values. In Calabresi’s later words, their book was a “more or less explicit appeal to anthropology for help.”1 Today, sociolegal studies remain well-poised to answer this appeal. Taking theory about moral costs from Calabresi in L&E and adding anthropological thought on the meaning of “value,” this essay presents situated valuation – a contextualized notion of value that accounts for the moral costs of inequalities while supporting principled scrutiny of redistributive policies meant to reduce inequality but sometimes worsening it. This discussion highlights the importance of interpretive social science in the study of distributive inequality, while showcasing a neglected but generative link between mutually imbricated interdisciplinary communities.
Are solidarity and identification as people of color distinct? Validating new measures across Asian, Black, Latino, and Multiracial Americans
Authors: Pérez Efrén , Goldman Seth K. , Huo Yuen J. , Nteta Tatishe , Tropp Linda R. 
Published: November 2024

Abstract
Mounting U.S. research suggests many non-White individuals feel solidarity with, and identify as, people of color (PoC). Yet measurement limitations prevent scholars from testing whether these constructs are empirically different. We explain why these concepts diverge and evaluate our claims with an expanded battery of measures across U.S. Asian, Black, Latino, and Multiracial adults (N = 3402). Using multi-group confirmatory factor analysis, we show these items capture related but distinct concepts among PoC (configural invariance). We then establish that these items uniformly measure each construct across PoC groups (metric invariance), with mean level differences validly reflecting actual heterogeneity between groups, rather than measurement artifacts (scalar invariance). Finally, consistent with our conceptualization, we show that solidarity among PoC mediates the association between PoC identification and support for policies that implicate various communities of color. We end with practical advice for using these items in surveys of racially diverse populations.
Gender, Paid Employment, and Deindustrialization in New Towns in North-West England, c. 1970–1990s
Authors: Pennington Eve 
Published: November 2024

Abstract
Existing research into the deindustrialization that afflicted northern England and Scotland during the twentieth century has focused predominantly on men’s experiences of unemployment and strikes. In contrast, this article examines the relationship between women’s employment and deindustrialization through the lens of three new towns in north-west England. Skelmersdale, Runcorn, and Central Lancashire were established during the 1960s and 1970s, partly with the aim of attracting employers and workers to a region experiencing industrial decline. Competing constructions of women’s work, both paid and unpaid, informed how the towns were planned, managed, and experienced. The new towns widened employment opportunities for female workers, but they did not significantly reshape gender roles because women remained responsible for housework and childcare while men were conceptualized as breadwinners. To explore this contradiction, the article analyses archival material produced by the development corporations that planned the new towns, alongside original oral history interviews conducted with women who lived and worked in them. It argues that even in situations of deindustrialization and rising male unemployment, women’s jobs did not displace men’s. Rather, the new towns represented a continuation of and a departure from existing patterns of employment, demonstrating that state-led urban development was fraught with gendered tensions.
Sleep and nutrition for athletes. The Nutrition Society, Scottish Section Conference 2024
Authors: Doherty Rónán , Madigan Sharon , Warrington Giles , Ellis Jason G 
Published: November 2024

Abstract
Sleep is vital for the maintenance of physical and mental health, recovery and performance in athletes. Sleep also has a restorative effect on the immune system and the endocrine system. Sleep must be of adequate duration, timing and quality to promote recovery following training and competition. Inadequate sleep adversely impacts carbohydrate metabolism, appetite, energy intake and protein synthesis affecting recovery from the energy demands of daily living and training/competition related fatigue. Sleep’s role in overall health and well-being has been established. Athletes have high sleep needs and are particularly vulnerable to sleep difficulties due to high training and competition demands, as such the implementation of the potential nutritional interventions to improve sleep duration and quality is commonplace. The use of certain nutrition strategies and supplements has an evidence base i.e. carbohydrate, caffeine, creatine, kiwifruit, magnesium, meal make-up and timing, protein and tart cherry. However, further research involving both foods and supplements is necessary to clarify the interactions between nutrition and the circadian system as there is potential to improve sleep and recovery. Additional research is necessary to clarify guidelines and develop products and protocols for foods and supplements to benefit athlete health, performance and/or recovery. The purpose of this review is to highlight the potential interaction between sleep and nutrition for athletes and how these interactions might benefit sleep and/or recovery.
Associations among environmental unpredictability, changes in resting-state functional connectivity, and adolescent psychopathology in the ABCD study
Authors: Yang Yumeng , Kong Tianjiao , Ji Feng , Liu Ran , Luo Liang 
Published: November 2024

AbstractBackgroundUnpredictability is a core but understudied dimension of adversities and has been receiving increasing attention recently. The effects of unpredictability on psychopathology and the underlying neural mechanisms, however, remain unclear. It is also unknown how unpredictability interacts with other dimensions of adversities in predicting brain development and psychopathology of youth.MethodsWe applied cluster robust standard errors to examine how unpredictability was associated with the developmental changes in resting-state functional connectivity (rsFC) of large-scale brain networks implicated in psychopathology, as well as the moderating role of deprivation, using data from the Adolescent Brain Cognitive Development (ABCD) study, which included four measurements from baseline (mean ± s.d. age, 119.13 ± 7.51 months; 2815 females) to 3-year follow-up (N = 5885).ResultsAfter controlling for threat, unpredictability was associated with a smaller increase in rsFC within default mode network (DMN) and a smaller decrease in rsFC between cingulo-opercular network (CON) and DMN. Neighborhood educational deprivation moderated the associations between unpredictability and changes in rsFC within DMN and fronto-parietal network (FPN), as well as between CON and DMN. A smaller decrease in rsFC between CON and DMN mediated the association between unpredictability and externalizing problems. Neighborhood educational deprivation moderated the indirect pathway from unpredictability to externalizing problems via a smaller decrease in CON-DMN rsFC.ConclusionsOur findings shed light on the neural mechanisms underlying the associations between unpredictability and adolescents' psychopathology and the moderating role of deprivation, highlighting the significance of providing stable environment and abundant educational opportunities to facilitate optimal development.
Theory driven psychological therapy for persecutory delusions: trajectories of patient outcomes
Authors: Jenner Lucy , Payne Mollie , Waite Felicity , Beckwith Helen , Diamond Rowan , Isham Louise , Collett Nicola , Emsley Richard , Freeman Daniel 
Published: November 2024

AbstractBackgroundWe aimed to identify the common types of outcome trajectories for patients with psychosis who take up specialist psychological therapy for persecutory delusions. Knowing the different potential responses to therapy can inform expectations. Further, determining predictors of different outcomes may help in understanding who may benefit.MethodsWe analyzed delusion conviction data from 767 therapy sessions with 64 patients with persistent persecutory delusions (held with at least 60% conviction) who received a six-month psychological intervention (Feeling Safe) during a clinical trial. Latent class trajectory analysis was conducted to identify groups with distinct outcome profiles. The trajectories were validated against independent assessments, including a longer-term follow-up six months after the end of therapy. We also tested potential predictors of the trajectories.ResultsThere were four outcome trajectories: (1) Very high delusion conviction/Little improvement (n = 14, 25%), (2) Very high delusion conviction/Large improvement (n = 9, 16%), (3) High delusion conviction/Moderate improvement (n = 17, 31%) and (4) High delusion conviction/Large improvement (n = 15, 27%). The groups did not differ in initial overall delusion severity. The trajectories were consistent with the independent assessments and sustained over time. Three factors predicted trajectories: persecutory delusion conviction, therapy expectations, and positive beliefs about other people.ConclusionsThere are variable responses to psychological therapy for persecutory delusions. Patients with very high delusion conviction can have excellent responses to therapy, though this may take a little longer to observe and such high conviction reduces the likelihood of positive responses. A trajectory approach requires testing in larger datasets but may prove highly informative.
Adenovirus 41 diversity in Arizona (USA) using wastewater-based epidemiology, long-range PCR, and pathogen sequencing between October 2019 and March 2020
Authors: Faleye Temitope O. C. , Skidmore Peter , Elyaderani Amir , Adhikari Sangeet , Kaiser Nicole , Smith Abriana , Yanez Allan , Perleberg Tyler , Driver Erin M. , Halden Rolf U. , Varsani Arvind , Scotch Matthew 
Published: November 2024

Abstract
By coupling long-range polymerase chain reaction, wastewater-based epidemiology, and pathogen sequencing, we show that adenovirus type 41 hexon-sequence lineages, described in children with hepatitis of unknown origin in the United States in 2021, were already circulating within the country in 2019. We also observed other lineages in the wastewater, whose complete genomes have yet to be documented from clinical samples.
Bioactive components in the marsupial pouch and milk
Authors: Jayamanna Mohottige Manujaya W. , Gardner Chloe E. , Nye-Wood Mitchell G. , Farquharson Katherine A. , Juhász Angéla , Belov Katherine , Hogg Carolyn J. , Peel Emma , Colgrave Michelle L. 
Published: November 2024

Abstract
Marsupials give birth to immunologically naïve young after a relatively short gestation period compared with eutherians. Consequently, the joey relies significantly on maternal protection, which is the focus of the present review. The milk and the pouch environment are essential contributors to maternal protection for the healthy development of joeys. In this review, we discuss bioactive components found in the marsupial pouch and milk that form cornerstones of maternal protection. These bioactive components include immune cells, immunoglobulins, the S100 family of calcium-binding proteins, lysozymes, whey proteins, antimicrobial peptides and other immune proteins. Furthermore, we investigated the possibility of the presence of plurifunctional components in milk and pouches that are potentially bioactive. These compounds include caseins, vitamins and minerals, oligosaccharides, lipids and microRNAs. Where applicable, this review addresses variability in bioactive components during different phases of lactation, designed to fulfil the immunological needs of the growing pouch young. Yet, there are numerous additional research opportunities to pursue, including uncovering novel bioactive components and investigating their modes of action, dynamics, stability and ability to penetrate the gut epithelium to facilitate systemic effects.
Mediterranean diet and oral health: is there an association? A scoping review
Authors: Popovac Aleksandra , Jaćimović Jelena , Trichopoulou Antonia , Peppa Eleni , Kotrokois Kostas , Stančić Ivica , Milić-Lemić Aleksandra , Kossioni Anastassia 
Published: November 2024

Abstract
As the Mediterranean diet (MDi) has demonstrated a powerful preventative effect on various medical conditions, a positive effect on oral health may also be speculated. Tooth loss, pain or tooth mobility may discourage the consumption of specific food types, affecting MDi adherence. The aim of this study was to investigate the association between adherence to MDi and oral health in adult populations. The study protocol was registered in Open Science Framework (https://osf.io/vxbnh/) and adhered to PRISMA-ScR guidelines. The principal research questions were: (1) Does better oral health enable adults to better adhere to MDi? and (2) Does better adherence to MDi enable adult individuals to have better oral health? The content of three databases, Clarivate Analytics’ Web of Science, Scopus and PubMed was searched without language, date or any other restrictions. The search results were imported into the Rayyan environment, and from the initial 1127 studies identified, only 20 remained after the exclusion process. Three articles composed the first group, revealing significant associations between various oral health parameters and adherence to MDi, with large variations in methodology and no safe conclusions. The studies investigating the effect of the level of adherence to MDi on various oral parameters were more numerous and revealed negative associations with the prevalence of periodontal disease and upper aero-digestive tract cancer. Further studies to explore the existence and direction of the association between oral health and MDi are needed, with public health interventions encouraging adherence to the MDi to reduce the burden of oral conditions and other non-communicable diseases.
Oocyte competence develops: nuclear maturation synchronously with cytoplasm maturation
Authors: Torkashvand Hossein , Shabani Ronak , Artimani Tayebe , Amiri Iraj , Pilehvari Shamim , Torkashvand Leila , Mehdizadeh Rana , Mehdizadeh Mehdi 
Published: November 2024

SummaryHuman oocyte maturation is a lengthy process that takes place over the course of which oocytes gain the inherent ability to support the next developmental stages in a progressive manner. This process includes intricate and distinct events related to nuclear and cytoplasmic maturation. Nuclear maturation includes mostly chromosome segregation, whereas rearrangement of organelles, storage of mRNAs and transcription factors occur during cytoplasmic maturation.Human oocyte maturation, both in vivo and in vitro, occurs through a process that is not yet fully understood. However, it is believed that the second messenger, cyclic adenosine monophosphate (cAMP), plays a pivotal role in the upkeep of the meiotic blocking of the human oocyte. Relatively high levels of cAMP in the human oocyte are required to maintain meiosis blocked, whereas lower levels of cAMP in the oocyte enable meiosis to resume. Oocyte cAMP concentration is controlled by a balance between adenylate cyclase and phosphodiesterases, the enzymes responsible for cAMP generation and breakdown.In addition to nuclear maturation, the female gamete requires a number of complicated structural and biochemical modifications in the cytoplasmic compartment to be able to fertilize normally. According to ultrastructural studies, during the transition from the germinal vesicle stage to metaphase II (MII), several organelles reorganize their positions. The cytoskeletal microfilaments and microtubules found in the cytoplasm facilitate these movements and regulate chromosomal segregation.The aim of this review is to focus on the nuclear and cytoplasmic maturation by investigating the changes that take place in the process of oocytes being competent for development.
A qualitative needs assessment of early participants in an Enhanced Recovery After Surgery program in CHD
Authors: Buehne Kristen L. , Winder Melissa , Marietta Jennifer , Park Jamie , Dwyer Murphy , Eckhauser Aaron W. , Hummel Kevin 
Published: November 2024

AbstractAlthough medical advancements have improved the mortality of CHD, morbidity still exists, impacting patient quality of life. Returning to baseline in the early surgical recovery phase is an area of potential improvement. This preliminary project aims to qualitatively understand CHD family perspectives concerning the immediate postoperative recovery phase. The participating patients enrolled in the Enhanced Recovery After Surgery program, a postsurgical symptom management tool utilised in adult centres and broadening into pediatrics. Twenty-three of 27 contacted families answered open-ended questions 1 to 3 months postoperatively regarding difficulties experienced during their first week home. They reviewed a list of symptoms including: difficulties with pain, nausea, activity, sleep, appetite, bowel or urinary systems, and taking medications. A qualitative thematic analysis was performed with the open responses, as well as a quantitative assessment of the types of issues that made recovery challenging. Participants struggled most with sleep (78%), returning to activity (70%), and pain (57%). Open-ended responses suggested that an inability to do daily activities, sleep (frequently impacted by pain), and inadequate resources most negatively impacted recovery. Given these findings, investigating postoperative sleep regimens and effective pain plan components may prove useful, in addition to the further development of early mobility programs. The positive and negative experiences highlighting the desire for readily available medical guidance enforce the need for open communication between families and team members, potentially aided by digital tools. Ultimately, further data could support the development of a standardised protocol to better the immediate postoperative quality of life for CHD families.
The Effects of Empathic Reactions to the Overturning of Roe v. Wade on Campaign Participation and Voter Turnout: Evidence from the 2022 U.S. Midterm Elections
Authors: Sirin Cigdem V. , Villalobos José D. 
Published: November 2024

AbstractIn June 2022, the U.S. Supreme Court’s Dobbs ruling overturned Roe v. Wade, reversing the nearly 50-year-old landmark decision that affirmed a woman’s constitutional right to abortion. Several months later, voters turned out in record numbers for the 2022 midterms, though a widely predicted “Red Wave” vote did not materialize. There has since been speculation that overturning Roe v. Wade played a crucial role in the midterms, generating a “Blue Tsunami” or “Roevember” driven largely by young, pro-choice women voting out of self-interest. We posit instead that group empathy was the key motivational mechanism in the link between opposition to Dobbs and voter mobilization in that election. Analyzing data from an original national survey, we find that opposition to overturning Roe v. Wade did not directly affect one’s likelihood to vote unless one is empathic toward groups in distress. Such opposition was actually demobilizing for those low in empathy. The findings indicate group empathy serves as a catalyst for people to act on their opposition to policies that harm disadvantaged groups, in this case women as a marginalized political minority losing their constitutional right to bodily autonomy and access to reproductive care.