bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Rare Cause of Inguinal Herniation: Bladder Herniation
Authors: TÜRKOĞLU Sefa , BEDEL Cihan 
Published: January 2019

Urinary
bladder presenting as an inguinal hernia is an uncommon condition found in
about 1-3% of inguinal hernia. Most
are asymptomatic, but symptoms such as dysuria, urgency, nocturia and
haematuria can be seen.
Computed tomography seems the best imaging choice to outline the details of
herniation. This study aims
to raise awareness for emergency physicians for the inguinal bladder herniation and to avoid misdiagnosis.
A comparative study of sublingual versus oral misoprostol following oral mifepristone for second trimester termination of pregnancy
Authors: Gupta Ruchi , Banerjee Krishna Priya , Pant Reena 
Published: January 2019

Background: The objective of this study is to assess the effectualness and safety of sublingual versus oral misoprostol following oral mifepristone for second trimester termination of pregnancy.Methods: This institution based contingent study was conducted on 220 women requesting for mid-trimester termination of pregnancy between 12-20 weeks with legal indication as per Govt. MTP act. After excluding the women as per exclusion criteria, they were randomly allocated into two groups (Group A Sublingual, Group B Oral), the women received 200 mg oral mifepristone followed by sublingual or oral misoprostol 400µg three hourly for a maximum of 5 doses 48 hours later. The course of misoprostol was reiterated if women failed to abort in 24 hours.Results: The mean induction-abortion interval of Group-A and Group -B was 4.02±1.39 hours and 6.44±1.79 hours respectively. The mean dose of misoprostol in Group–A and Group-B was 680±220.4µg and 1003.6±274.9µg. Hence mean Induction-abortion interval and dose were shortened in Group-A as compare to Group-B (p <0.05). There was 100% success rate noticed via both routes. Evacuation was done in 4 (3.64%) women in Group-B as compare to only 1 (0.91%) in Group-A . The acceptability was significantly more in Group-B (100%) as compare Group-A (52.73%), probably because of unpleasant taste of sublingual misoprostol. All side effects (Nausea, pain, headache, and diarrhea) were common in both the Groups, only fever was significantly more common in sublingual group as compare to oral group (p<0.05).Conclusions: From present study authors conclude that, sublingual misoprostol when combined with mifepristone is effective for medical abortion in second trimester in terms of effectualness, endurability and success rate than oral route.
An observational study to compare between conventional condom balloon catheter with CG balloon
Authors: Xess Somila , Baghel Preeti 
Published: January 2019

Background: Postpartum haemorrhage (PPH) is a life-threatening complication of delivery. The most common cause of PPH is uterine atony. Intrauterine balloon tamponade has been suggested as an effective, easily administered minimally invasive treatment option to control uterine bleeding while preserving the mother’s ability to bear additional children.Methods: Twenty women with normal vaginal delivery were studied over a period of six months, 10 were inserted conventional balloon tamponade and rest 10 were inserted CG balloon and outcome studied in terms of time to assemble, leakage, expulsion, lumen occlusion, volume of fluid used, time to arrest bleeding, cost, drainage port, inflation deflation interval.Results: Most of the women were para 4 or more, unbooked belonging to age group of 20-30. Mean time to assemble Condom balloon tamponade was 1.8min and that in CG balloon was 1.2 minute. There was leakage and expulsion in two and lumen occlusion in three in the conventional balloon catheter. In the second group there was no leakage ,lumen occlusion or expulsion . There is uterine drainage port present in CG balloon which is characteristic of it which helps in determining the actual blood loss in real time. The inflation deflation interval and mean volume of fluid are almost same in both the groups.Conclusions: Both conventional balloon and CG balloon are effective and lifesaving in low resource setting with few advantages of CG balloon over conventional balloon tamponade.
Prospective study of maternal perception of decreased fetal movement in third trimester and evaluation of its correlation with perinatal compromise
Authors: Nandi Nupur , Agarwal Ritika 
Published: January 2019

Background: Intrauterine fetal movements are sign of fetal life and well being. Perception of decreased fetal movements by the expecting mother is a common concern for both the mother and her obstetrician. Inadequate evaluation of reported decreased fetal movements may lead to catastrophic perinatal outcome. These necessitates us to identify the mothers perceiving decreased fetal movements, evaluating them to identify any risk factor, and follow up them to know the correlation with perinatal outcome.Methods: Antenatal mothers with singleton pregnancy at third trimester are recruited from OPD/ Emergency of Obstetrics and Gynaecology departments of Teerthankar Mahaveer Medical College and Research Center, Moradabad, Uttar Pradesh, India. Both case and control group comprise of 80 mothers matched by demographic profile, with perception of decreased fetal movements only in case group. They were evaluated thoroughly to identify risk factor if any and were followed up till delivery to know the perinatal outcome.Results: Majority of women reporting reduced fetal movements were between 20-30 years of age group (73%), Primigravida (80%), 72.5% were at term pregnancy. Common (46%) pattern of decreased movements was both in frequency and as well as intensity. 62% women with decreased fetal movements had anteriorly placed placenta. In the study group, 48.75% women were identified with risk factor, and association of more than one antenatal risk factor was significantly high (p value 0.0026). LBW was more common (21.25%), many neonates were associated with low Apgar score in the study group.Conclusions: Pregnant mothers reported with decreased fetal movement in third trimester should be evaluated adequately for identification of risk factors, as well as for fetal surveillance. Record of fetal movement for 2 hours while the mother is in rest, Cardiotocography, elaborative USG, BPP should be monitored to have good perinatal outcome by providing timely intervention.
Cerebral venous sinus thrombosis a study to assess clinical profile among female patients in a tertiary care hospital
Authors: Gujjar Amruth , Babu Sudindra , E. Kalinga B. 
Published: January 2019

Background: The Incidence of Cerebral Venous Thrombosis (CVT) is around 3-4 cases among one million population affecting children and young adults. In India the puerperal CVT is 10-12 times more common than western countries. Even though there is apparent “rarity” of the condition but advances in knowledge and available investigation in terms of imaging (CT scan/MRI) diagnosis can be done early for appropriate treatment and decreasing the morbidity and mortality.Methods: A prospective study was conducted at Karnataka Institute of Medical Sciences, Hubli, Karnataka from December 2014 to November 2015. A total of 36 patients were included in the study.Results: Mean age of females in the study was 27.06±9.033years. 75% had seizures, 47.2% had headache, 19.4% had focal neurological deficit, 13.9% had altered sensorium, 8.3% had cranial nerve deficits 5.6% had speech deficits. 72.22% of patients and were in peripartum period and 27.8% were non-pregnant. 72.2% had superior sagittal sinus involvement, 47.2% had transverse sinus, 47.2% had sigmoid sinus, and 13.9% had internal jugular vein and 5.6% straight sinus. 47.2% had single sinus involvement, and 52.8% had multiple sinus involvement. 94.4% patients were managed conservatively and 5.6% were managed by neurosurgical intervention. 94.4% patients survived and 5.6% had mortality.Conclusions: Cerebral venous sinus thrombosis is most common in young females during peripartum period. Early diagnosis, treatment and if necessary neurosurgical intervention has good outcome.
Ultrasonographic and fine needle aspiration cytology correlation of thyroid gland lesions: a study of 100 cases
Authors: Patel Nehal R. , Patel Alpesh V. , Patel Vaibhav V. , Vadher Payal R. , Kakadia Manali B. 
Published: January 2019

<p class="abstract"><strong>Background:</strong> Thyroid gland is unique among endocrine organs as it is the largest endocrine gland in the body and the first to develop in the fetal life. There is approximately 4-5% incidence of clinically apparent thyroid lesions in general population. The goal of USG and FNAC diagnosis work up now is to select those patients for surgery who have a high likelihood of harboring malignancy in the nodule. Ultrasonography is the single most valuable imaging modality in the evaluation of the thyroid gland. Indications for thyroid USG include evaluation for palpable thyroid lesion or suspected thyroid enlargement and workup of thyroid lesions discovered incidentally.The present study is undertaken to evaluate the utility of FNAC in preoperative diagnosis of various thyroid lesions and to evaluate the efficacy of in USG and FNAC differentiating between benign and malignant lesions.</p><p class="abstract"><strong>Methods:</strong> A retrospective clinical study, 100patients, in the age group of equal to or above 18 years, with thyroid swellings, referred to the department of ENT, sent for USG and FNAC at radiology and pathology department during the period from July 2014 to July 2016. </p><p class="abstract"><strong>Results:</strong> Out of 100 cases, 6% were malignant, 94% were benign on grey scale ultrasound. Out of 6 malignant cases 2 cases were confirmed malignant by FNAC.</p><p class="abstract"><strong>Conclusions:</strong> High resolution grey scale ultrasound has emerged as initial imaging modality of choice for the evaluation of patients with thyroid enlargement. Ultrasound can detect solitary nodule, multiple nodules and diffuse thyroid enlargement. It can also differentiate solid and cystic lesions.</p>
Neurotrofiny: ewolucja podejść do eksperymentalnej naprawy ośrodkowego układu nerwowego
Authors: Skup Małgorzata 
Published: January 2019

Neurotrophins (NT) were âbrought to life” by Rita Levi-Montalcini and Stanley Cohen, thanks to their discovery of the nerve growth factor (NGF) isolated from the malignant tumor. A hint got from the cancer studies on the presence of NTs and other molecules like metalloproteases, which control neuronal remodeling and extracellular matrix in tumors, was the stimulus to investigate the role of these molecules in physiology and post-lesion plasticity of the nervous system. NTs have long been identified as drivers of neurogenesis during development and regeneration of the nervous system. Thousands of investigations spanned from early sixties till now provided strong evidence that this small family of molecules is indispensable for central and peripheral nervous system maintenance throughout the whole life of different animal species. In mammals NTs regulate sensation, movement, behavior, and cognition. A problem, which accompanies the majority of experimental therapies using NTs following injury of the nervous system, stems from unspecific and uncontrolled stimulation of the whole circuitry of preserved neurons. Among the already identified causes of clinical trial failure with the use of NT therapy in the treatment of neurodegenerative diseases are: (1) disregarding neuronal preferences to selected NTs; (2) poor knowledge on NT pharmacokinetics (3) uncontrolled spread of NTs when administered systemically, which could have unpredictable effects on other than intended neuronal populations (4) limitations of tissue penetration of some NTs (5) disturbances of the balance between signal transmission through their Trk and LNGTR receptors. I present our contribution to the field and efforts to control spatially and temporally postinjury NT signaling.
Postpartum Maternal Health at a Time of Rapid Societal Change in Abu Dhabi, United Arab Emirates
Authors: Gardner Hazel , Green Katherine , Gardner Andrew Somerville , Geddes Donna 
Published: January 2019

Background. Abu Dhabi has undergone a rapid transition from a subsistence economy to a wealthy modern state over the last 50 years. This paper presents an insight into the health status of Emirati mothers during this transition through a prospective longitudinal study of mothers who gave birth in a government maternity hospital in the Emirate of Abu Dhabi.Methods. 125 women were interviewed within the first week after birth, as part of a larger study encompassing a wide range of cultural, social, and behavioural aspects of health. They were then re-interviewed at three, six and 15 months postpartum. A food frequency questionnaire was also administered to the mothers at birth. Data were analysed using univariate statistics.Results. Over 70% of the mothers had BMI in the overweight and obese categories, and approximately half of the women were dissatisfied with their weight. Contributing factors were likely to be diets high in fats and sugar, low levels of exercise and women’s limited involvement in household food purchasing and preparation. Iron deficiency anaemia, diabetes, asthma and fertility problems were found to be the most common concerns amongst the participants prior to conception. Anaemia rates were high during pregnancy, with 35% having haemoglobin < 11 g/dL, and were positively associated with parity. Belief in traditional and herbal medicines was strong, with 43% of women using a variety of remedies during pregnancy.Conclusions. Policies and support mechanisms to encourage women to make better dietary choices and to provide more opportunities for exercising are required to improve the health of mothers in the UAE. The development of good quality health care has resulted in the better maternal health outcomes, although traditional practices in relation to herbal medicines are still common.
The Impact of Skipping Breakfast on the Body Weight of Children and Young People in Saudi Arabia; A Systematic Review
Authors: Alhilabi Hanan Saleem , Payne Anne 
Published: January 2019

Aim: To review evidence on the impact of skipping breakfast on the body weight of children and young people of Saudi Arabia. Method: A systematic search of the Cochrane Library, EBSCO (AMED, MEDLINE, and CINAHL), Web of Science, SCOPUS, PubMed, and EMBASE was conducted in March 2018 to identify primary published research. Additional studies were identified by hand searching in other sources such as subject-specific journals and grey literature. Any observational study, published in the English language in the last 20 years (1998-2018), involving healthy children and/or young people (5-24 years) in Saudi Arabia was included and the effect of skipping breakfast on their body weight was evaluated. Pre-defined information was extracted from each study onto a data extraction form for evaluation, following the Cochrane method for undertaking a systematic review. Study quality was evaluated using a Quality Assessment Tool for Quantitative Studies. Results: Eight studies met the inclusion criteria, of which seven graded weak in quality assessment, while one paper scored moderate. Six studies show that regular breakfast consumption has a protective effect against overweight/obesity, of which three studies tested the correlation, while controlling for confounding variables. Two of the eight studies demonstrated no significant correlation. Breakfast intake was also found to have a positive association with student's academic performance, with two out of three trials demonstrating a significant relationship, but in linking regular breakfast habit with socioeconomic status, no effect was found. Conclusion: The findings suggest that skipping breakfast is associated with a higher risk of overweight and obesity in children and adolescents in Saudi Arabia and thus breakfast consumption is associated with a reduced risk of overweight and obesity. However, in view of the array of methods used to define breakfast skipping and overweight/obesity, as well as the less robust nature of observational studies we cannot conclusively assume this relationship, suggesting further more controlled studies are required. Key words: Obesity, overweight, breakfast, breakfast skipping, children, young people, Saudi Arabia.
Effects of caloric restriction on anthropometrical and specific performance in highly-trained university judo athletes
Authors: CHRARA Lalia , A.Raoui RIAD , Belkadi Adel , ASLI Hocine , BENBERNOU Othman 
Published: January 2019

Purpose:The purpose of this study was to determine the ultimate body mass, performance, and nutritional characteristics of the Algerian judo junior athletes, and also analysing the impact of nutritional intakes on stabilising Weight loss according to special performance of judo athletes. Material:Twenty-one male university athletes (aged: 21.45 ± 1.32; height: 1.81 ± 0.45 m; and body mass: 73.9 ± 4.1 kg) participated in this study during a period of stabilising Weight loss before and after 15 days of caloric restriction. Athletes were submitted to anthropometrical measurements and performed the Special Judo Fitness Test. Values for nutrient intakes were obtained from a 15 day food record kept during a training camp period of Weight maintenance and after a 15-day caloric restriction.Results:caloric restriction resulted in significant decreases in body mass (73.73 ± 2.1) and performance. However, Special Judo Fitness Test index increased significantly (14.00 ± 1.75) during caloric restriction in comparison to stabilising Weight loss.Conclusion:Exercise and caloric restriction lead to determine the ultimate Weight and physical performance. The present study provides baseline nutritional data that can be used in the prescription of individual training programs for university judo Athletes.
Food Safety Knowledge among Chicken Shawerma Food Handlers in Amman- Jordan
Authors: M Al-Nasraween , L Al Omari , M Al-Jaghbeer , R Al-Qutob , V Berggren , H Taha 
Published: January 2019

Aims: Several food poisoning outbreaks in Jordan were due to Salmonella species isolated from chicken shawerma. This study aimed to assess the food safety knowledge among chicken shawerma food handlers in Jordan. Methods: Forty chicken shawerma restaurants in Amman were selected randomly and 120 food handlers (Egyptians 53%, Jordanians 26% and Syrians 19%) were interviewed using a structured questionnaire. Descriptive and multivariate data analysis was conducted to assess their knowledge about food safety. Results: Low overall mean score of food safety knowledge (40%); the mean percent of correct answers about transportation, receiving of chicken shawerma, storage, preparation, selling, and controlling microorganisms were: 63%, 54%, 45%, 31%, and 26%, respectively. Ninety percent of the participants had no previous training in food safety concepts. Better food safety knowledge was significantly associated (p > 0.05) with higher educational levels, receiving special training in food safety and having a Jordanian nationality. Conclusions: This study recommends establishing a comprehensive food safety program in Jordan to build the capacity of the food handlers and enforce periodic evaluation of their food safety knowledge and evidence-based best practices.
Validation of the Persian version of dysphagia in multiple sclerosis questionnaire for the assessment of dysphagia in multiple sclerosis
Authors: Jafari Zahra , Shahbodaghi Mohammad Rahim , Maroufizadeh Saman , Naser Moghadasi Abdorreza 
Published: January 2019

Background: About one third of patients with multiple sclerosis (MS) experience dysphagia. Dysphagia can cause complications such as malnutrition, lung infections, aspiration pneumonia and dehydration, thus it is very helpful to diagnose dysphagia as soon as possible. The aim in this study was to translate dysphagia in multiple sclerosis (DYMUS) questionnaire into Farsi and and validate it.
Methods: Forward-backward method was used to translate original English version of DYMUS into farsi, and then the questionnaire (one for each patient) was filled in through asking questions from 200 patients with MS by a speech and language pathologist. Confirmatory factor analysis (CFA) was used to examine the construct validity. Internal consistency and test-retest reliability of the DYMUS were evaluated using Cronbach’s alpha and the intraclass correlation coefficient (ICC), respectively.
Results: CFA showed that a two-factor model of DYMUS including “dysphagia for solid” and “dysphagia for liquid” fitted the data well [relative chi-square [χ2/degree of freedom (df) = 1.55, CFI = 0.967, Tucker-Lewis index (TLI) = 0.957, root mean square error of approximation (RMSEA) = 0.053, and weighted root mean square residual (WRMR) = 0.874]. The Cronbach’s alpha for total score and liquid and solid subscales were 0.776, 0.557, and 0.725, respectively. The DYMUS showed
adequate test-retest reliability for the total and subscales (ICC: 0.880-0.956). Moreover, this study has shown a significant relationship between DYMUS score and Expanded Disability Status Scale (EDSS) score, disease duration, type of MS, and self-reported dysphagia.
Conclusion: The Persian version of DYMUS is a reliable and valid tool to screen dysphagia among patients with MS.
Polymorphisms of serotonin transporter gene and psychological status in patients with multiple sclerosis
Authors: Farjadian Shirin , Fakhraei Bahareh , Niknam Zahra , Nasiri Mahboubeh , Azad Aslan , Farjam Mojtaba , Nikseresht Alireza 
Published: January 2019

Background: Multiple sclerosis (MS) is the most common neuroinflammatory disease in young adults. Anxiety and depression may predispose individuals to MS and flare-ups. Serotonin transmission is modified in some brain regions of patients with MS, and these changes may contribute to their psychiatric abnormalities. We studied the frequencies of common polymorphisms of the serotonin reuptake transporter (SERT) gene in patients with MS according to their psychological status.
Methods: The 5-HTTLPR, rs25531, and STin2VNTR polymorphisms of the SERT gene were genotyped by polymerase chain reaction (PCR)-based methods in 100 patients with MS and 100 healthy controls.
Results: There were no remarkable differences in SERT gene polymorphisms between patients with MS and healthy controls. Unlike the control group, 41% of the patients showed some degree of depression based on Beck Depression Inventory (BDI), but no association was observed between SERT gene polymorphisms after the patients were stratified by depression status.
Conclusion: In addition to SERT gene
polymorphisms, modulation of serotonin at the synapses may also be regulated by genetic variations in tryptophan hydroxylase type 2 and serotonin receptors. Further studies with functional brain imaging of the serotonergic system in patients with MS can provide information on the role of serotonin in this disease.