bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementing ‘The Zones of Regulation’ for Autistic Students: Teacher Perceptions and Practices
Authors: Love Abigail M. A. , Gibbs Vicki , Roxburgh Danielle G. , Dorn Elizabeth A. , Cai Ru Ying 
Published: November 2024

AbstractThe Zones of Regulation (The Zones) is an 18-lesson curriculum that is aimed at helping students develop an awareness of emotions and skills for regulation. Although used by schools globally, no peer-reviewed evidence currently exists to support the use of The Zones. The purpose of this study was to examine the experiences of teachers implementing The Zones curriculum with autistic students. Feedback was gathered from 26 teachers throughout their implementation of The Zones. In this study, we employed a qualitative methodology to analyse the feedback from teachers. Descriptive statistics were used to report on acceptability, appropriateness, and feasibility. Our findings revealed that teachers described high levels of acceptability, appropriateness, and feasibility when reflecting on the delivery of The Zones. However, teachers reported that The Zones was not suitable for all students and classrooms. For students for whom The Zones was deemed appropriate, teachers modified the lessons and required peer support to deliver these modifications. With modifications, the teachers observed growth in areas such as students’ comprehension of others’ emotions and improved language around emotions. This study highlights the importance of further research to refine and tailor interventions like The Zones to better meet the diverse needs of autistic students in educational settings.
How Does Media Coverage of Corporate Social Irresponsibility Influence Cross-Border Acquisition Completion? Evidence from Chinese MNEs
Authors: Oh Won-Yong , Zeng Rong (Ratchel) , Oh Chang Hoon 
Published: November 2024

Abstract
Previous studies have found that media coverage of a firm's corporate social irresponsibility (CSiR) often delays or blocks the completion of a cross-border acquisition when the acquiror is a multinational enterprise (MNE) from an emerging market. Drawing from the attention-based view, we argue that the effects of Chinese MNEs’ CSiR on deal completion vary depending on several contextual factors, as these factors garner more attention by making the deals more salient to stakeholders. Using a sample of cross-border acquisitions by Chinese MNEs from 2013 to 2020, we find that CSiR media coverage per se does not decrease the likelihood of a deal's completion. However, consistent with attention-based arguments, we find that CSiR media coverage negatively affects the deal's completion when the acquirors are state-owned enterprises and when the target country has high institutional quality. Our findings enhance our understanding of the effects of CSiR on cross-border acquisitions by highlighting the moderating roles of contextual factors related to stakeholder attention. Thus, it is important for MNEs to recognize the boundary conditions that may influence the potential sanctions from local stakeholders. Based on these findings, this study contributes to the literature on CSiR, cross-border acquisitions, and stakeholder attention.
Novel dissolved organic 14C analyses method applied in a case study at a LILW waste repository
Authors: Molnár A , Veres M , Varga T , Turza P , Jull A J T , Janovics R , Molnár M 
Published: November 2024

AbstractA routine chemical procedure was developed at the Ede Hertelendi Laboratory of Environmental Studies (HEKAL), in Debrecen which can measure the dissolved organic radiocarbon content of groundwater as well as the inorganic and total fraction. The typical background of this non-purgeable dissolved organic radiocarbon preparation is 0.73 ± 0.14 percent modern carbon (pMC), using a carbon contamination correction on fossil dissolved material (potassium hydrogen phthalate) samples.
Older mothers produce smaller eggs without compromising offspring quality: a study of a thelytokous mite predator (Acari: Phytoseiidae)
Authors: Zhang Keshi , Liu Zhenguo , Zhang Zhi-Qiang 
Published: November 2024

AbstractNegative relationships between the parental age and offspring life history traits have been widely observed across diverse animal taxa. However, there is a lack of studies examining the influence of parental age on offspring performance using mites, particularly phytoseiid predators as subjects. This study explored the influence of maternal age on offspring life history traits in Amblyseius herbicolus (Chant) (Acari: Mesostigmata), a phytoseiid predatory mite reproducing through thelytokous parthenogenesis. We hypothesised that increased maternal age negatively impacts offspring traits, including developmental duration, body size, fecundity and lifespan. Amblyseius herbicolus was reared under controlled laboratory conditions, and the life history traits of offspring from mothers of varying ages were analysed using linear mixed-effect models. Our results showed that the increase in maternal age significantly reduced individual egg volume, but did not significantly affect offspring developmental duration, body size, fecundity or lifespan. These findings indicate that while older A. herbicolus females produced smaller eggs, the subsequent performance (i.e. body size, fecundity and lifespan) of offspring remained largely unaffected, suggesting possible compensatory mechanisms in the offspring or alternative maternal provisioning strategies. The results of this study offer useful insights into the reproductive strategies of phytoseiid predators and asexually reproducing species, enhancing our understanding of how maternal age affects offspring fitness. Further studies can examine how offspring of A. herbicolus from mothers of different ages perform under adverse environmental conditions.
Mythical Mythology: Mythical Objects, Intentional Identity, and Referential Anti-Realism
Authors: Alward Peter 
Published: November 2024

Abstract
I defend a referential anti-realist solution to the problem of intentional identity. I develop Nathan Salmon's referential realist solution to the problem — according to which mythical objects exist and we can refer to them by using mythical-object names — and consider David Braun's objections to it. I argue that Salmon's solution yields the real identity, rather than the intentional identity, of the objects of multiple subjects’ thoughts. And I develop a referential anti-realist variant of Salmon's view — according to which mythical objects do not exist nor are they otherwise real but we can nevertheless refer to them — which avoids this worry.
Product of polynomial values being large power
Authors: Mazumdar Eshita , Roy Arindam 
Published: November 2024

AbstractErdös and Selfridge first showed that the product of consecutive integers cannot be a perfect power. Later, this result was generalized to polynomial values by various authors. They demonstrated that the product of consecutive polynomial values cannot be the perfect power for a suitable polynomial. In this article, we consider a related problem to the product of consecutive integers. We consider all sequences of polynomial values from a given interval whose products are almost perfect powers. We study the size of these powers and give an asymptotic result. We also define a group theoretic invariant, which is a natural generalization of the Davenport constant. We provide a non-trivial upper bound of this group theoretic invariant.
Prevalence study of Echinococcus granulosus in guanaco (Lama guanicoe) from the Chilean Patagonia unexpectedly reveals the southernmost limit of Taenia omissa
Authors: Alvarez Rojas Cristian A. , Alvarez Juan Francisco , Iglesias Juliana , Koehler Anson V. , Bonacic Cristian 
Published: November 2024

Abstract
This study presents the first detection of Taenia omissa metacestodes in guanaco (Lama guanicoe) within the Chilean Patagonia, marking the southernmost record of natural infection in an intermediate host on the continent. Taenia omissa was found in the continental part of the Magallanes region where the top predators are pumas (Puma concolor). Conversely, all metacestodes found in guanacos collected from Tierra del Fuego Island, where no pumas exist, were identified solely as Echinococcus granulosus sensu stricto. Additionally, this research highlights a tissue preference of T. omissa for liver, contrasting with E. granulosus, which predominantly affects the lungs in guanacos. We also report the infection of T. pisiformis in 1 guanaco. Our findings emphasize the need for accurate identification of metacestodes during meat inspection in an area where T. omissa and E. granulosus overlap. This research also contributes to increase the knowledge of parasite–host dynamics in wildlife and underscores the importance of considering broader spectrum intermediate hosts in the epidemiology of parasitic infections.
Functional gradient dysfunction in drug-naïve first-episode schizophrenia and its correlation with specific transcriptional patterns and treatment predictions
Authors: Yao Guanqun , Luo Jing , Li Jing , Feng Kun , Liu Pozi , Xu Yong 
Published: November 2024

AbstractBackgroundFirst-episode schizophrenia (FES) is a progressive psychiatric disorder influenced by genetics, environmental factors, and brain function. The functional gradient deficits of drug-naïve FES and its relationship to gene expression profiles and treatment outcomes are unknown.MethodsIn this study, we engaged a cohort of 116 FES and 100 healthy controls (HC), aged 7 to 30 years, including 15 FES over an 8-week antipsychotic medication regimen. Our examination focused on primary-to-transmodal alterations in voxel-based connection gradients in FES. Then, we employed network topology, Neurosynth, postmortem gene expression, and support vector regression to evaluate integration and segregation functions, meta-analytic cognitive terms, transcriptional patterns, and treatment predictions.ResultsFES displayed diminished global connectome gradients (Cohen's d = 0.32–0.57) correlated with compensatory integration and segregation functions (Cohen's d = 0.31–0.36). Predominant alterations were observed in the default (67.6%) and sensorimotor (21.9%) network, related to high-order cognitive functions. Furthermore, we identified notable overlaps between partial least squares (PLS1) weighted genes and dysregulated genes in other psychiatric conditions. Genes linked with gradient alterations were enriched in synaptic signaling, neurodevelopment process, specific astrocytes, cortical layers (layer II and IV), and developmental phases from late/mid fetal to young adulthood. Additionally, the onset age influenced the severity of FES, with discernible differences in connection gradients between minor- and adult-FES. Moreover, the connectivity gradients of FES at baseline significantly predicted treatment outcomes.ConclusionsThese results offer significant theoretical foundations for elucidating the intricate interplay between macroscopic functional connection gradient changes and microscopic transcriptional patterns during the onset and progression of FES.
Effects of aerobic exercise on hippocampal formation volume in people with schizophrenia – a systematic review and meta-analysis with original data from a randomized-controlled trial
Authors: Roell Lukas , Fischer Tim , Keeser Daniel , Papazov Boris , Lembeck Moritz , Papazova Irina , Greska David , Muenz Susanne , Schneider-Axmann Thomas , Sykorova Eliska , Thieme Cristina E. , Vogel Bob O. , Mohnke Sebastian , Huppertz Charlotte , Roeh Astrid , Keller-Varady Katriona , Malchow Berend , Stoecklein Sophia , Ertl-Wagner Birgit , Henkel Karsten , Wolfarth Bernd , Tantchik Wladimir , Walter Henrik , Hirjak Dusan , Schmitt Andrea , Hasan Alkomiet , Meyer-Lindenberg Andreas , Falkai Peter , Maurus Isabel 
Published: November 2024

AbstractBackgroundThe hippocampal formation represents a key region in the pathophysiology of schizophrenia. Aerobic exercise poses a promising add-on treatment to potentially counteract structural impairments of the hippocampal formation and associated symptomatic burden. However, current evidence regarding exercise effects on the hippocampal formation in schizophrenia is largely heterogeneous. Therefore, we conducted a systematic review and meta-analysis to assess the impact of aerobic exercise on total hippocampal formation volume. Additionally, we used data from a recent multicenter randomized-controlled trial to examine the effects of aerobic exercise on hippocampal formation subfield volumes and their respective clinical implications.MethodsThe meta-analysis comprised six studies that investigated the influence of aerobic exercise on total hippocampal formation volume compared to a control condition with a total of 186 people with schizophrenia (100 male, 86 female), while original data from 29 patients (20 male, 9 female) was considered to explore effects of six months of aerobic exercise on hippocampal formation subfield volumes.ResultsOur meta-analysis did not demonstrate a significant effect of aerobic exercise on total hippocampal formation volume in people with schizophrenia (g = 0.33 [−0.12 to 0.77]), p = 0.15), but our original data suggested significant volume increases in certain hippocampal subfields, namely the cornu ammonis and dentate gyrus.ConclusionsDriven by the necessity of better understanding the pathophysiology of schizophrenia, the present work underlines the importance to focus on hippocampal formation subfields and to characterize subgroups of patients that show neuroplastic responses to aerobic exercise accompanied by corresponding clinical improvements.
The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety
Authors: Monistrol-Mula Anna , Felez-Nobrega Mireia , Byrne Enda M. , Lind Penelope A. , Hickie Ian B. , Martin Nicholas G. , Medland Sarah E. , Colodro-Conde Lucía , Mitchell Brittany L. 
Published: November 2024

AbstractBackgroundGenetic vulnerability to mental disorders has been associated with coronavirus disease-19 (COVID-19) outcomes. We explored whether polygenic risk scores (PRSs) for several mental disorders predicted poorer clinical and psychological COVID-19 outcomes in people with pre-existing depression.MethodsData from three assessments of the Australian Genetics of Depression Study (N = 4405; 52.2 years ± 14.9; 76.2% females) were analyzed. Outcomes included COVID-19 clinical outcomes (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] infection and long COVID, noting the low incidence of COVID-19 cases in Australia at that time) and COVID-19 psychological outcomes (COVID-related stress and COVID-19 burnout). Predictors included PRS for depression, bipolar disorder, schizophrenia, and anxiety. The associations between these PRSs and the outcomes were assessed with adjusted linear/logistic/multinomial regressions. Mediation (N = 4338) and moderation (N = 3326) analyses were performed to explore the potential influence of anxiety symptoms and resilience on the identified associations between the PRSs and COVID-19 psychological outcomes.ResultsNone of the selected PRS predicted SARS-CoV-2 infection or long COVID. In contrast, the depression PRS predicted higher levels of COVID-19 burnout. Anxiety symptoms fully mediated the association between the depression PRS and COVID-19 burnout. Resilience did not moderate this association.ConclusionsA higher genetic risk for depression predicted higher COVID-19 burnout and this association was fully mediated by anxiety symptoms. Interventions targeting anxiety symptoms may be effective in mitigating the psychological effects of a pandemic among people with depression.
Diagnostic profiles among suicide decedents with and without borderline personality disorder
Authors: Kaufman Erin A. , Coon Hilary , Shabalin Andrey A. , Monson Eric T. , Chen Danli , Staley Michael J. , Keeshin Brooks R. , Docherty Anna R. , Bakian Amanda V. , DiBlasi Emily 
Published: November 2024

AbstractBackgroundBorderline personality disorder (BPD) is a debilitating condition characterized by pervasive instability across multiple major domains of functioning. The majority of persons with BPD engage in self-injury and up to 10% die by suicide – rendering persons with this condition at exceptionally elevated risk of comorbidity and premature mortality. Better characterization of clinical risk factors among persons with BPD who die by suicide is urgently needed.MethodsWe examined patterns of medical and psychiatric diagnoses (1580 to 1700 Phecodes) among persons with BPD who died by suicide (n = 379) via a large suicide death data resource and biobank. In phenotype-based phenome-wide association tests, we compared these individuals to three other groups: (1) persons who died by suicide without a history of BPD (n = 9468), (2) persons still living with a history of BPD diagnosis (n = 280), and (3) persons who died by suicide with a different personality disorder (other PD n = 589).ResultsMultivariable logistic regression models revealed that persons with BPD who died by suicide were more likely to present with co-occurring psychiatric diagnoses, and have a documented history of self-harm in the medical system prior to death, relative to suicides without BPD. Posttraumatic stress disorder was more elevated among those with BPD who died by suicide relative to the other PD group.ConclusionsWe found significant differences among persons with BPD who died by suicide and all other comparison groups. Such differences may be clinically informative for identifying high-risk subtypes and providing targeted intervention approaches.
Exosc10 deficiency in the initial segment is dispensable for sperm maturation and male fertility in mice
Authors: Zhou Meiyang , Yu Junjie , Xu Yu , Li Hong , Feng Yan-Qin , Wang Xiao , Qiu Fanyi , Li Nana , Wang Zhengpin 
Published: November 2024

SummaryEXOSC10 is an exosome-associated ribonuclease that degrades and processes a wide range of transcripts in the nucleus. The initial segment (IS) of the epididymis is crucial for sperm transport and maturation in mice by affecting the absorption and secretion that is required for male fertility. However, the role of EXOSC10 ribonuclease-mediated RNA metabolism within the IS in the regulation of gene expression and sperm maturation remains unknown. Herein, we established an Exosc10 conditional knockout (Exosc10 cKO) mouse model by crossing Exosc10F/F mice with Lcn9-Cre mice which expressed recombinase in the principal cells of IS as early as post-natal day 17. Morphological and histological analyses revealed that Exosc10 cKO males had normal spermatogenesis and development of IS. Moreover, the sperm concentration, morphology, motility, and frequency of acrosome reactions in the cauda epididymides of Exosc10 cKO mice were comparable with those of control mice. Thus, Exosc10 cKO males had normal fertility. Collectively, our genetic mouse model and findings demonstrate that loss of EXOSC10 in the IS of epididymis is dispensable for sperm maturation and male fertility.
Sinus node dysfunction in children: different aetiologies, similar clinical course in two-centre experience
Authors: Tunca Sahin Gulhan , Kurt Cemil Cihad , Kafali Hasan Candas , Sevinc Sengul Fatma , Haydin Sertac , Ozgur Senem , Guzeltas Alper , Ergul Yakup 
Published: November 2024

AbstractAim:This study aims to evaluate the clinical characteristics and outcomes of children diagnosed with sinus node dysfunction.Methods:This was a retrospective review of patients diagnosed with sinus node dysfunction in two tertiary paediatric cardiology centres in Turkey from January 2011 to June 2022.Results:In all, 77 patients (50, 64.9% males) were included, with a mean age of 8.2 ± 6.3 years and a mean weight of 28.2 ± 18.8 kg. While age-incompatible bradycardia and pauses were the most common rhythm disturbances, syncope, presyncope, and dizziness (n:33, 43%) were the most frequent initial symptoms. Structural heart disease was present in 58 (75.3%) of the 77 patients, 47 (61%) of whom were congenital. The most commonly associated CHDs were transposition of the great arteries (n:8), atrial septal defect (n:7), and atrioventricular septal defect (n:5). Seven of them also had left atrial isomerism. The remaining 19 patients were isolated. Four patients had SCN5A mutation (two of them were siblings) and two of them had Emery–Dreifuss muscular dystrophy.Conclusion:Although sinus node dysfunction is rare in children, it has been diagnosed with increasing frequency with structural heart disease, especially in patients who have undergone corrective cardiac surgery related to atrial tissue. Since sinus node dysfunction can occur at any time postoperatively, these patients should be kept under constant control. If symptomatic sinus node dysfunction is confirmed, permanent pacing is an effective therapeutic modality.
The Matter and Form of Kant’s Moral Law
Authors: Biondi Zachary 
Published: November 2024

Abstract
There is an interpretative puzzle at the centre of Kant’s Groundwork for the Metaphysics of Morals. The text presents the single principle of morality (G, 4: 392), but instead of providing a definitive statement of the principle, we find a three-step sequence of formulas. The puzzle concerns the formula relation: given the contrast between the moral law’s individuality and the plurality of formulas, how do the formulas relate to each other and the moral law? This paper takes the first step towards a new account by focusing on G, 4: 436, a passage in which Kant makes claims about the matter and form of the moral law. By understanding the hylomorphism entailed by these claims, it is possible to achieve new perspectives on common questions about Kant’s ethics, in particular, the role of the formulas in deriving or explaining duties and how the formulas are used in the argument of Groundwork II and its transition from popular moral philosophy to metaphysics of morals.
Asymptotic behavior of bond yields and volatilities for the extended 3/2 model under the real-world measure
Authors: Fergusson Kevin 
Published: November 2024

AbstractThe extended
$3/2$
short rate model is a mean reverting model of the short rate which, for suitably chosen parameters, permits a sensible term structure of bond yields and closed-form valuation formulae of zero-coupon bonds and options. This article supplies proofs of the formulae for the expected present values of future cash flows under the real-world probability measure, known as actuarial valuation. Finally, we give formulae for asymptotic levels of bond yields and formulae for bond option prices for the extended
$3/2$
model, under particular conditions on its parameters.