bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH METODE EKSPERIMEN TERHADAP KONSENTRASI ANAK BERKEBUTUHAN KHUSUS DALAM PEMBELAJARAN SAINS
Authors: Khamidun Diana , Khoiroh Elif Mauzidatuf 
Published: July 2018

The research objective is to provide accurate information and picture about the influence of the experimental method to the concentration of children with disabilities in beginning science activities. The research was carried out in the Training Park and Observation of Foreign School in Semarang, with a total sample 14 early age children with special needs. This study used an experimental design providing a group with treatment to see the influence. T-test was used to prove the hypothesis that the experimental method can have a significant influence on the concentration of children with disabilities to learn beginning science. Experimental method as a learning method in preschool classes in the institution of early childhood development, can influence the children’s ability/concentration in learning. This method gives children the opportunity to know and interact with the environment and enable them to focus and concentrate on learning activities in the classroom.
MENINGKATKAN KEMAMPUAN BERBICARA ANAK MELALUI BERMAIN RODA GAMBAR
Authors: Wulandari Addiniah Sukmawati 
Published: July 2018

The purpose of this research is to improve speaking skills of children aged 6-7 years by playing a picture wheel in SDN Rawamangun 15 Pagi, Jakarta Timur. This research using action research method that was done by two cycle consisting of planning, acting, observing, and reflecting. The research subject are children aged 6-7 years who had problem in the ability of speaking as many as 8 childrens. The analysis of data was obtained from the comparison between the ability of childrens speaking before and after implemetation of the action. The final result from the overall analysis of data percentage reach to 78,3%. Based on the percentage of end the cycle of this research, so it was stated that the hypothesis can be accepted. Then it can be concluded that playing a picture wheel can improved children speaking ability of aged 6-7 years. The implication of this research is playing a picture wheel can be alternative for improving children speaking ability of aged 6-7 years. The reach of children speaking ability can showed by word producing, conveying the idea, asking the question, expressing emotion, and conveying the information.
PENGEMBANGAN KARAKTER ANAK USIA DINI MELALUI SIMULASI KECAKAPAN HIDUP
Authors: Widayati Tri 
Published: July 2018

The purposes of this research were do describe the process of character building through life skill simulation and to develop the childrenâ€™s character through life skill simulation. This action research was conducted in three early childhood education institutions for six months started from March through July 2013. The researcher did the research in collaboration with the local teachers to assess, plan, implement, observe, and do reflection. T test indicated a significant difference between the character development degree before and after the simulation. The hindrances in developing the character through life skill simulation are the childrenâ€™s shy feeling and low self-confidence as well as the teachersâ€™ limitation in designing the simple, interesting, and easy simulation scenario.
Assessment of Nature Tourism Potential, in Rural Development in West Wollega Zone in The Case of Sayo Nole and Nole Kaba Districts, Ethiopia
Authors: Soressa Temesgen 
Published: July 2018

<p>Tourism is not just the temporary movement of people to destinations outside their normal places. Tourism includes many geographic, economic, environmental, social, cultural and political dimensions. A tourism industry has a strong relationship with those dimensions because of its dependency and impact on it, and the interests of its stakeholders (Kauffmann 2008).</p><p>As stated by Sinha (2007) the study of tourism is the study of people away from their usual habitat of the establishments which responds to the requirement of travelers and the impact of that they have on the economic physical and social well-being of their hosts. Tourism is an attractive tool for economic development, specifically in the developing world. Viewed as an export industry of three Gs -- "get them in, get their Money, and get them out" – tourism has assisted many developing countries to move away from a dependency on agriculture and manufacturing (Tooman, 1997. </p><p>Chosen forits ability to bring in needed foreign exchange earnings, income and employment, tourism has become a popular addition to economic development policies in many African, Asian, South and Central American countries. Although tourism seems to beading substantially to the economic growth of many of these regions, many developing countries are not reaping full benefits from tourism (Vaugeois, 1990).</p><p>Tourism in Ethiopia dates back to the pre-Axumite period when the first illustrated travel guides to Ethiopia can be found in the friezes of the pyramids and ancient sites of Egypt. These depicted travels to the land of Punt, which the Egyptians knew was the source of the Nile, and where they traded for gold, incense, ivory and slaves. The fourth century Persian historian Mani described the Kingdom of Axum as being one of the four great empires of the world, ranking it alongside China, Persia and Rome (World Bank, 2006). Modern tourism in Ethiopia can be said to have started with the formation of a government body to develop and control it in 1961: The Ethiopian Tourist Organization (Y.Mulualem, 2010).</p>
Muslim Education in Murshidabad, a Bengal District during 1704-1947: A Review
Authors: Rumi Emili 
Published: July 2018

<p>The historic city of Murshidabad-the earstwhile nawabi capital –a city founded in the year 1704 by Murshid Quli Khan, the Mughal diwan of Bengal. In 1704 Murshid Quli Khan transferred the capital of Bengal from Dhaka to Murshidabad and named the city after his name .The town is situated on the left bank of river Bhagirathi. It is the northern most district of the Presidency Division of West Bengal and lies between 23 o 43’ and 24 o 52’ north latitude and 87 0 49’ and 88 0 44’ east longitude .<strong> </strong>Under the Nawabs Murshidabad’s glory reached to the highest peak in almost all arenas. As a trading centre Murshidabad became famous. Many scholars came here and settled and they mixed with the local people freely and there developed a cosmopolitan culture. According o Sushil Chaudhury ‘‘It was a golden day of Murshidabad under the Nawabs’’.<strong> </strong>By the middle of the 18<sup>th</sup> century Murshidabad became one of the greatest centre of culture and education as the nawabs were the patrons of learned persons. But after the battle of Plassey the scenario of Murshidabad started changing .With the establishment of the British power we see gradual decline of its culture and education. Many of the British policies directly affected Murshidabad such as the shifting of court to Calcutta, introduction of permanent settlement, introduction of western education and declaration of English as the official language instead of Persian. Murshidabad is the only district of West Bengal where Muslims outnumbered the Hindus since 1901 and formed the majority community. Presently this district is a backward district of West Bengal .When we enquire the causes of this backwardness we find education as one of the major causes. The present paper is a modest attempt to analyse the educational progress in Murshidabad under the Nawabs and also under the British. The paper will also enquire the causes of educational backwardness of this district.</p>
Promoting English Vocabulary for Autistic Students by Using Speech Therapy (An Action Research in Sunan Muria Extraordinary School, Kudus)
Authors: Romadlon Farid Noor 
Published: July 2018

The opportunity to learn English should be given to all learners since English has been widely spread globally. Learners should be exposed to English as early as possible and be prevalent for all, including disabled students. Students who need special treatment in learning should also get equal opportunity to study, especially English. One type of disabled students who need special attention in English learning is those who have autism. Autistic students are in need of special treatment learning English since they have more difficulties in perceiving and producing language code. Therefore, English teachers should have awareness of the characteristics of autistic students concerning speech difficulties. It is highly necessary for autistic students to have intensive therapy and in other sides, they also have a right to learn foreign languages like English. Speech therapy as one of the therapies used to assist the autistic students in producing language codes is potentially in line with English learning. In this case, speech therapy can be done while teaching English to autistic students because speech therapy often requires graded language teaching. This study focuses on how speech therapy is integrated with English teaching for autistic students in Second Grader of Junior High School students to improve their English proficiency and speech competence as well. The study is an ongoing classroom action research conducted in SMP Sunan Muria in Kudus Regence, Central Java, Indonesia.
Novel Benzylidenehydrazide-1,2,3-Triazole Conjugates as Antitubercular Agents: Synthesis and Molecular Docking
Authors: Shaikh Mubarak H. , Subhedar Dnyaneshwar D. , Nawale Laxman , Sarkar Dhiman , Khan Firoz A. Kalam , Sangshetti Jaiprakash N. , Shingate Bapurao B. 
Published: July 2018

Background & Objectives:Novel 1,2,3-triazole based benzylidenehydrazide derivatives were synthesized and evaluated for antitubercular activity against Mycobacterium tuberculosis (MTB) H37Ra, M. bovis BCG and cytotoxic activity. Most of the derivatives exhibited promising in vitro potency against MTB characterized by lower MIC values.Methods:Among all the synthesized derivatives, compound 6a and 6j were the most active against active and dormant MTB H37Ra, respectively. Compound 6d was significantly active against dormant and active M. bovis BCG.Results:The structure activity relationship has been explored on the basis of anti-tubercular activity data. The active compounds were also tested against THP-1, A549 and Panc-1 cell lines and showed no significant cytotoxicity. Further, the synthesized compounds were found to have potential antioxidant with IC50 range = 11.19-56.64 µg/mL. The molecular docking study of synthesized compounds was performed against DprE1 enzyme of MTB to understand the binding interactions.Conclusion:Furthermore, synthesized compounds were also analysed for ADME properties and the potency of compounds indicated that, this series can be considered as a starting point for the developement of novel and more potent anti-tubercular agents in future.
Metformin one in a Million Efficient Medicines for Rheumatoid Arthritis Complications: Inflammation, Osteoblastogenesis, Cardiovascular Disease, Malignancies
Authors: Rajaei Elham , Haybar Habib , Mowla Karim , Zayeri Zeinab D. 
Published: July 2018

Background:
Rheumatoid arthritis is a widespread autoimmune disease and inflammation
and bone destruction are two main issues in rheumatoid arthritis.

Objective:
To discussing metformin effects on rheumatoid arthritis complications.

Methods:
: We conducted a narrative literature search including clinical trials, experimental studies
on laboratory animals and cell lines. Our search covered Medline, PubMed and Google Scholar databases
from 1999 until 2018. We used the terms” Metformin; Rheumatoid arthritis; Cardiovascular
disease; Cancer; Osteoblastogenesis.

Discussion:
Inflammatory pro-cytokines such as Interlukin-6 play important roles in T. helper 17
cell lineage differentiation. Interlukin-6 and Tumor Necrosis Factor-α activate Janus kinase receptors
signal through signaling transducer and activator of transcription signaling pathway which
plays important role in inflammation, bone destruction and cancer in rheumatoid arthritis patients.
Interlukin-6 and Tumor Necrosis Factor-α synergistically activate signaling transducer and activator
of transcription and Nuclear Factor-kβ pathways and both cytokines increase the chance of cancer
development in rheumatoid arthritis patients. Metformin is AMPK activators that can suppress
mTOR, STAT3 and HIF-1 so AMPK activation plays important role in suppressing inflammation
and osteoclastogenesis and decreasing cancer.

Conclusion:
Metformin effect on AMPK and mTOR pathways gives the capability to change
Treg/Th17 balance and decrease Th17 differentiation and inflammation, osteoclastogenesis and
cancers in RA patients. Metformin can be useful in protecting bones especially in first stages of RA
and it can decrease inflammation, CVD and cancer in RA patients so Metformin beside DAMARs
can be useful in increasing RA patients’ life quality with less harm and cost.</P>
Significance of miR-15a-5p and CNKSR3 as Novel Prognostic Biomarkers in Non-Small Cell Lung Cancer
Authors: Ergun Sercan , Güney Serkan , Temiz Ebru , Petrovic Nina , Gunes Sezgin 
Published: July 2018

Background:
In recent years, targeted cancer treatment methods at various molecular levels have
been developed for Non-Small Cell Lung Cancer (NSCLC), one of two major subtypes of lung cancer. miRNAbased
clinical trials are currently the preferred targeted therapeutic strategy. Also, ceRNAs (competing endogenous
RNA) would be the newest and the most effective approach to uncover novel interactions between mRNAs
and miRNAs in NSCLC carcinogenesis. There are many factors influencing the efficiency of a miRNA to suppress
or silence translation of the target mRNA. The most effective event is the presence of other RNAs showing
ceRNA activity. These RNAs contain binding sites for specific miRNAs and enable miRNAs to bind these
pseudo targets, instead of the original binding sites on the target mRNA. Therefore, the mRNA of the target
gene is less affected by this miRNA, while the amount of miRNA remains the same in the media.

Method:
For this project, we determined that five clinically important different oncogenes (PDL1, FGFR1,
DDX3X, SLC1A5, FXR1 ) are involved in the pathogenesis of NSCLC. For this purpose, we transfected model
NSCLC cell line, A549, with miRNAs (miR-150-5p, miR-15a-5p, miR-503-5p) targeting these oncogenes to
investigate whether these oncogenes will be suppressed at the mRNA level and also how the suppression efficiency
of these miRNA on the oncogenes will be affected by possible ceRNA (CNKSR3, POU2F1, HIPK2)
activities.

Results:
miR-15a-5p was determined to have the most suppressive effect on the five genes and three potential
ceRNAs (p<0.05). Furthermore, CNKSR3 was the ceRNA most affected by all three miRNAs (p<0.05).

Conclusion:
CNKSR3 was affected more than the oncogenes known to act on NSCLC and this might make it a
stronger and novel marker for use in possible treatment regimens designed using miR-15a-5p silencing effect on
oncogenes in NSCLC pathogenesis. According to the literature, this is the first study associating NSCLC with
miR-15a-5p and CNKSR3.
Internalisasi nilai-nilai kejuangan Jenderal Soedirman dalam pendidikan karakter di SMA Taruna Nusantara
Authors: Wibowo Mokhammad Unggul , Suryo Djoko , Siswoyo Dwi 
Published: July 2018

Penelitian ini bertujuan untuk mendeskripsikan: (1) nilai-nilai kejuangan Jenderal Soedirman yang diinternalisasi; (2) proses internalisasi nilai-nilai kejuangan Jenderal Soedirman; dan (3) efektivitas internalisasi nilai-nilai kejuangan Jenderal Soedirman di SMA Taruna Nusantara. Penelitian ini adalah deskriptif kualitatif dengan pendekatan fenomenologi. Pengumpulan data menggunakan wawancara, observasi, dan studi dokumentasi. Analisis data menggunakan model analisis data kualitatif Miles & Huberman. Hasil penelitian menunjukkan bahwa nilai-nilai kejuangan Jenderal Soedirman yang diinternalisasi di SMA Taruna Nusantara belum dirumuskan secara eksplisit. Internalisasi nilai-nilai kejuangan Jenderal Soedirman dilaksanakan pada tahapan pertama pendidikan karakter, menggunakan pendekatan inspiratif dan pola tindak pengajaran, pengasuhan, dan pelatihan. Internalisasi nilai-nilai kejuangan Jenderal Soedirman di SMA Taruna Nusantara telah memberikan pengetahuan moral (moral knowing) kepada para siswa. Nilai-nilai tersebut diinternalisasi oleh para siswa sehingga mereka memiliki perasaan moral (moral feeling). Dalam menghadapi permasalahan hidup, mereka mengaktualisasikan nilai-nilai kejuangan Jenderal Soedirman tersebut sebagai perilaku moral (moral action).Kata kunci: nilai kejuangan, internalisasi nilai, dan pendidikan karakter THE GENERAL SUDIRMAN STRUGGLE VALUES INTERNALIZATION IN CHARACTER EDUCATION IN TARUNA NUSANTARA SENIOR HIGH SCHOOLAbstractThis study aims to describe: (1) the General Sudirman struggle values which are internalized; (2) the process of the General Sudirman struggle value internalization; and (3) the effectiveness of the General Sudirman struggle values internalization in Taruna Nusantara Senior High School. This study is a qualitative descriptive by using phenomenology approach. Data collection using interviews, observation, and documentation studies. The data analysis used Miles & Huberman qualitative data analysis model. The study findings are the General Sudirman struggle values which are internalized in Taruna Nusantara Senior High School have not explicitly formulated. The General Sudirman struggle values internalization done in the first step of character education, using inspirative and teaching pattern approach, parenting, and training. The General Sudirman struggle values internalization in Taruna Nusantara Senior High School Magelang has effectively given moral knowing. Those values then internalized by the students so that they have moral feeling. In facing life problem, they actualize the General Sudirman Struggle Values as moral action.Keywords: struggle values, value internalization, character education
Metabolic Syndrome and Benign Prostatic Hyperplasia
Authors: Chhetri Raj Kumar , Baral Suman , Thapa Neeraj 
Published: July 2018

Introduction: Metabolic syndrome is defined as the presence of at least 3 of the following parameters: (1) waist circumference ≥ 90 cm, (2) triglycerides > 150 mg/dl or treatment for hypertriglyceridemia, (3) HDL-cholesterol < 40 mg/dl or treatment for reduced HDL-cholesterol, (4) blood pressure ≥ 130/85 mmHg or current use of antihypertensive medications, (5) fasting blood glucose ≥ 110 mg/dl or previous diagnosis of type-2 diabetes mellitus. It is closely associated with many diseases and recent studies have also shown its association with benign prostatic hyperplasia and lower urinary tract symptoms. Our study aimed to investigate association between metabolic syndrome and its components with benign prostatic hyperplasia among patients managed surgically in a tertiary centre in Western Nepal.
Methods: One hundred and four patients above 50 years with benign prostatic hyperplasia managed in the department of Surgery over one year were included in the study.
Results: Twenty-seven patients had metabolic syndrome (25.96%). There was association between metabolic syndrome and mean prostate size and among components of metabolic syndrome, high serum triglyceride and low HDL Cholesterol were found to be associated. There was increase in mean prostate size with increase in number of metabolic syndrome components which was statistically significant.
Conclusion: Metabolic syndrome along with its two components, serum triglyceride and HDL Cholesterol were associated with increase in mean prostate size.
REVIEW: Photojournalism—a welcome celebration and challenge
Authors: Peacock Colin 
Published: July 2018

Conflict, Custom and Conscience: Photojournalism and the Pacific Media Centre 2007-2017, edited by Jim Marbrook, Del Abcede, Natalie Robertson and David Robie. Auckland: Pacific Media Centre. 2017. 78 pages. ISBN 978-1-927184-45-5.
At an event marking 10 years of the Pacific Media Centre in Auckland in November 2017, Radio New Zealand journalist Johnny Blades said New Zealand’s role in establishing a ceasefire in Bougainville in 1998—and paving the way for a subsequent peace agreement—was an achievement New Zealanders should be proud of. 'We should be shouting about it from the rooftops,' he said. But sadly, he added, too few people seemed to know much about it these days.
Eksklusi sosial pada masyarakat Petani
Authors: Yunita, S.Sos., M.Si Desi 
Published: July 2018

Konsep eksklusi sosial yang digunakan oleh para sosiolog barat, saat ini juga telah berkembang dan menjadi kajian keilmuan sosial di Indonesia. Pertumbuhan penduduk dan kebijakan pembangunan yang dikembangkan oleh pemerintah di daerah pedesaan telah menimbulkan perubahan pada masyarakat petani. Artikel ini berfokus pada perubahan-perubahan yang menjadi pendorong terjadinya eksklusi sosial pada masyarakat petani, dan memperlihatkan bentuk-bentuk eksklusi sosial apa saja yang terjadi pada masyarakat petani khususnya di wilayah Jawa Barat.
O capitalismo como religião: intersecções e reflexões da religião de mercado a partir do pensamento de Agamben e Benjamin / Capitalism as religion: intersections and reflections of market religion from the thought of Agamben and Benjamin
Authors: Costa Otávio Barduzzi Rodrigues da 
Published: July 2018

Este artigo quer tecer considerações sobre o capitalismo como religião. Através da analise bibliográfica de vários autores, mas em especial de Giorgio Agamben e Walter Benjamin vai analisar como se dá a dinâmica do entendimento do capitalismo enquanto religião. Evidenciada a estreita conexão que existe entre a concepção do homem como animal industrioso e a exploração e concentração de renda como fim último, a maquina como o meio mais eficaz e o estado totalitário como promotor mais potente, não se torna difícil abrir uma inquisição cruel propriamente contra a concepção moderna do homem, o bem-estar, as máquinas e os estados capitalistas.AbstractThis article wants to make considerations about capitalism as a religion. Through the bibliographical analysis of several authors, but especially of Giorgio Agamben and Walter Benjamin will analyze how the dynamics of the understanding of capitalism as a religion occurs. Given the close connection between the conception of man as an industrious animal and the exploitation and concentration of income as the ultimate goal, the machine as the most effective means and the totalitarian state as the most powerful promoter, it is not difficult to open a cruel inquisition properly Against the modern conception of man, the welfare, the machines and the capitalist states.
The Agendas of Public Administration Reforms in Lithuania: Windows of Opportunity in the Period 2004 – 2017
Authors: Nakrošis Vitalis 
Published: July 2018

Abstract
The article analyses changes in the reform agendas of the Lithuanian government in the period 2004 – 2017. Instead of exploring the systemic and formal agendas of administrative reforms based on government strategies and programmes, it focuses on the institutional and actual agendas of Lithuanian authorities using a set of 20 reform initiatives. In addition to the analysis of the institutional context, we also assess a coupling logic and the exercise of political or bureaucratic entrepreneurship during reform policy making. The article finds that budgetary constraints and the reform policy priorities of the Lithuanian governments explain the ambitious agendas of administrative reforms during the 2008 – 2012 government and, to a lesser extent, during the 2016 – 2020 government. The political logic of coupling and political entrepreneurship dominated the flow of the reform process when these governments were in office, producing the top-down approach to reform policy making. In contrast, the 2004 – 2006, 2006 – 2008 and 2012 – 2016 governments relied strongly on a policy-centred logic of coupling together with bureaucratic entrepreneurship, which resulted in the bottom-up approach to administrative reforms in the country.