bluuebunny/crossref_metadata_2025_split huggingface dataset:
A preliminary analysis of biomechanics and saccadic responses for concussion
Authors: Post Andrew , Hashim Eyesha , Ting Windsor Kwan-Chun , Hoshizaki T. Blaine , Gilchrist Michael D. , Cusimano Michael D. 
Published: July 2019

Background Concussion is an injury that occurs in non-sporting and sporting environments. To determine improved clinical methods for identifying this injury, it is important to develop and understand how the impact event results in quantifiable differences in brain functioning—functioning that has been quantified in the past using saccadic measures. The purpose of this research was to examine the relationships between oculomotor deficits, specifically antisaccade responses, and the biomechanics of impact for a concussion. Methods Participants underwent a diffusion tensor imaging protocol as well as saccadic testing to determine differences in brain functioning in comparison to controls. The injury event was then reconstructed in laboratory using physical and finite element models to determine the biomechanics of the impact and brain tissue strain. Relationships between the biomechanical variables and antisaccade responses were then examined. Results The diffusion tensor imaging analyses found that there was a decrease in radial diffusivity and axial diffusivity found in the cerebral peduncle (p < 0.05) and cingulum hippocampus (p < 0.05), respectively. There was an increase in the axial diffusivity for the corona radiata (p < 0.05). The saccadic testing found an increase in mean latency for the concussed group (p < 0.05). The results indicated no significant relationship between mean latency, duration, amplitude and peak velocity antisaccade measures and the biomechanical variables. This may have been influenced not only by a lack of sensitivity in biomechanical variable to antisaccade responses, but also to these responses being affected by factors other than injury such as attentiveness and wakefulness. Conclusion While the sample of this research was small, this research suggests that to improve the understanding of the relationship between impact biomechanics and concussion, methods that can quantify the damage to brain structures through imaging, such as diffusion tensor imaging, may be more appropriate.
‘A bridge to normal’: a qualitative study of Indonesian women’s attendance in a phase two cardiac rehabilitation programme
Authors: Sutantri Sutantri , Cuthill Fiona , Holloway Aisha 
Published: July 2019

Background: Cardiac rehabilitation is effective in reducing mortality and morbidity, in improving life expectancy and quality of life for people with cardiovascular disease. Despite these recognised benefits, women’s attendance rates in cardiac rehabilitation programmes remain suboptimal. Aims: This paper details the study that explored factors that influence women’s attendance of a phase two cardiac rehabilitation programme in Indonesia Methods: An exploratory qualitative research design was used in the study. Semi-structured interviews were used as the main method of data collection. Data were collected from June to September 2016. Twenty-three women aged between 30 and 66 years were interviewed. Transcribed interview data were analysed using a qualitative framework analysis. Results: Three major themes were inferred from the analysis: (a) a bridge to normal; (b) connecting with others; and (c) contextual factors. The first theme is illustrated by two subthemes: ‘making my heart work again’ and ‘performing social roles’. The second theme was illustrated by the following subthemes: ‘exchanging knowledge and experience’ and ‘developing a give-and-take relationship’. The third theme was illustrated by three subthemes: ‘recommendations from the staff’, ‘family support’ and ‘availability of health insurance’. Conclusion: Women’s attendance in cardiac rehabilitation in Indonesia is mainly influenced by their expectations and desire to be able to resume their previous social roles in the family and society. The findings of this study can assist healthcare professionals to understand better the needs of women and the fit between women’s needs and existing cardiac rehabilitation programmes. Such understanding could provide direction for more effective approaches to the cardiac rehabilitation programmes that are currently offered in Indonesia.
Dysfunctional Cav1.2 channel in Timothy syndrome, from cell to bedside
Authors: Han Dan , Xue Xiaolin , Yan Yang , Li Guoliang 
Published: July 2019

Timothy syndrome is a rare disorder caused by CACNA1C gene mutations and characterized by multi-organ system dysfunctions, including ventricular arrhythmias, syndactyly, dysmorphic facial features, intermittent hypoglycemia, immunodeficiency, developmental delay, and autism. Because of the low morbidity and high mortality at a young age, it remains a huge challenge to establish a diagnosis and treatment system to manage Timothy syndrome patients. Here, we aim to provide a detailed review of Timothy syndrome, discuss the mechanisms underlying dysfunctional Cav1.2 due to CACNA1C mutations, and provide some new emerging evidences in treating Timothy syndrome from cell to bedside, promoting the management of this rare disease. Impact statement The knowledge of Timothy syndrome (TS) caused by dysfunctional Cav1.2 channel due to CACNA1C mutations is rapidly evolving as novel technologies of electrophysiology are introduced and our understanding of the mechanisms of TS develops. In this review, we focus on the TS-related dysfunctional Cav1.2 and the underlying mechanisms. We update TS-related CACNA1C mutations in a precise way over the past 20 years and summarize all reported TS patients based on their clinical presentations and molecular mechanisms, respectively. We hope this review will provide a new comprehensive way to better understand the electrophysiological mechanisms underlying TS from cell to bedside, promoting the management of TS in practice.
The association of gout with an increased risk of hypertension and diabetes mellitus among stroke survivors in New Zealand: A cross-sectional study using routinely collected electronic health data
Authors: San Gabriel Dina Eufemia D , Slark Julia 
Published: July 2019

Background There is a paucity of data relating to the association of gout with the occurrence of hypertension and diabetes mellitus in patients with stroke. This study aimed to determine the association of gout with the risk of hypertension and diabetes mellitus in a cohort of stroke patients from Auckland, Aotearoa New Zealand. Methods A cross-sectional study was conducted among stroke survivors in South and East Auckland, New Zealand from the years 2010 to 2014. Electronic health record data were collected and analysed using Statistical Package for Social Science version 23. Multivariate logistic regression modelling adjusted for age, gender, and ethnicity was conducted to determine the association of gout with the risk of hypertension and diabetes mellitus in patients discharged with a diagnosis of stroke. Results The age-, gender-, and ethnicity-adjusted odds ratio for having hypertension and diabetes mellitus among stroke survivors with gout history were 3.25 (95% confidence interval 1.32–8.03) and 1.94 (95% confidence interval 1.12–3.36), respectively. Māori stroke survivors with gout history had the highest risk of having diabetes mellitus with age- and gender-adjusted odds ratio of 5.10 (95% confidence interval 1.90–18.93). Conclusion The findings from this study suggest gout may be independently associated with an increased risk of hypertension and diabetes mellitus in patients with stroke. Māori who are the indigenous population of New Zealand show a greater risk of diabetes mellitus associated with a gout diagnosis compared to other populations. This finding highlights the importance of the need for further research with Māori stroke survivors and other indigenous populations.
An evaluation of a digital pain management programme: clinical effectiveness and cost savings
Authors: Pimm Theo John , Williams Laura Juliette , Reay Megan , Pickering Stephen , Lota Ranjeeta , Coote Laura , Maloney Ciara , Hancock David , Sarhan Firas 
Published: July 2019

Introduction: Chronic pain is one of the most prevalent causes of disability worldwide, and digital interventions may be one of the ways to meet this need. Randomised controlled trials have demonstrated that digital interventions can be effective in treating chronic pain. This study aimed to establish the clinical effectiveness of a web-based pain management programme (PMP), specifically whether it would lead to improved clinical outcomes and reduced health care costs in a real-world clinical setting. Methods: Of 738 participants, 438 engaged with the programme and 300 did not. Two analyses were conducted: a within-subjects pre–post comparison of clinical outcomes for participants who completed the programme and a between-groups comparison of health care usage for those who engaged and those who did not. Results: Participants who completed the programme made significant improvements with regard to their perceived health status, level of disability, mood, confidence managing pain, problems in life due to pain and level of pain. Around one-third of participants made reliable changes in their levels of disability, depression and anxiety. There was no relationship between gender or age and engagement with the programme. Those who engaged with the programme demonstrated reduced health care costs in the year following referral, whereas health care costs of non-engagers increased. Limitations of the study include a high drop-out rate and a non-randomised comparison group. Results must therefore be interpreted with some caution. Conclusion: A web-based pain management programme can be clinically effective and may be a useful addition to the treatments offered by pain management services.
Neurology Clerkship: Predictors of Objective Structured Clinical Examination and Shelf Performance
Authors: Sampat Ajay , Rouleau Gerald , O’Brien Celia , Zadikoff Cindy 
Published: July 2019

Background: We sought to determine whether the following factors are associated with stronger performance on the medical school neurology clerkship: (1) structure of the outpatient rotation (working with a single general neurologist or multiple subspecialists), (2) dedicated shelf exam preparation, and (3) clerkships completed prior to neurology rotation. Methods: A total of 439 Feinberg medical students between 2014 and 2016 were analyzed based on the 3 variables of interest listed above. Student performance was evaluated using the National Board of Medical Examiner shelf exam and Objective Structured Clinical Examination/standardized evaluation scores. Univariate and multivariate analyses were conducted. Results: The format of the 2-week outpatient rotation did not significantly affect shelf examination ( P = .59), or standardized evaluation ( P = .34) scores. Taking a shelf pre-test correlated with overall higher standardized evaluation scores ( P < .01), and higher shelf examination scores ( P < .01). No individual clerkship correlated with better performance; however, the total number of core clerkships was associated with higher shelf examination scores ( P = .007). Each additional core clerkship taken prior to neurology was associated with 0.72 points greater shelf examination score. Conclusions: Greater attending continuity did not appear to be associated with stronger performance perhaps due to a difference in types of cases observed. Students who took a practice shelf exam did better on both their shelf exam and standardized evaluation, suggesting that acquisition of knowledge translates to a better clinical performance. No individual clerkship offers an advantage, but rather it is the total number of clerkships that is correlated with stronger performance.
Proper dissipative torques in antiferromagnetic dynamics
Authors: Yuan H. Y. , Liu Qian , Xia Ke , Yuan Zhe , Wang X. R. 
Published: July 2019

Abstract
There is little doubt that the magnetization dynamics of ferromagnetic systems is governed by the Landau-Lifshitz-Gilbert equation or its generalization with various spin torques. In contrast, there are several sets of dynamic equations for two-sublattice antiferromagnets (AFMs) in the literature that have different forms of dissipative torques and no proper dynamic equations for multi-sublattice AFMs and ferrimagnets in general. Here we introduce the general Rayleigh dissipation functional into the Lagrange equation and derive the proper form of the dissipative torques in the phenomenological equations for the AFMs with multiple sublattices. A new type of dissipative torque arising from the inter-sublattice drag effect is discovered which has important effects on the magnon lifetime and domain wall motion.
Hydrogen/Deuterium Isotopic Labeling Study of Enantioselective Hydrogenation of (E)-2-Methyl-2-butenoic Acid over a Cinchonidine-Modified Pd/C Catalyst
Authors: Sugimura Takashi , Tomatsuri Satoshi , Fujita Morifumi , Okamoto Yasuaki 
Published: July 2019

Abstract
In the enantioselecitve hydrogenation of (E)-2-methyl-2-butenoic acid (1) over a cinchonidine-modified Pd/C catalyst, the addition of hydrogen preferentially proceeds from the Re-Si enantioface of the C=C double bond of 1 to yield (S)-2-methylbutanoic acid ((S)-3). Double bond migration of 1 takes place under the reaction conditions and is followed by immediate hydrogenation to yield 3 in a poor enantiomeric purity. Deuterium labeling experiments at 0.1 MPa and 1.9 MPa of D2 verified the previous assumption of competitive double bond migration. The combination of isotopic labeling experiments and chiral analysis revealed that the double bond migration of 1 proceeds with the same enantiofacial differentiation as the hydrogenation of 1. Thus, interaction of 1 with cinchonidine adsorbed on the Pd surface may control the configuration of the double bond migration and the hydrogenation.
Preliminary assessment of the utilization of durian peel liquid smoke as a natural preservative for mackerel
Authors: Faisal Muhammad , Gani Asri , Mulana Farid 
Published: July 2019

Background: Durian peel is a type of biomass waste that contains cellulose, hemicelluloses, and lignin. The pyrolysis of these compounds results in production of liquid smoke which can be used as a natural preservative to replace current synthetic preservatives. This research assessed the ability of liquid smoke produced during pyrolysis of durian peel to preserve fish. Methods: Dry durian peel waste underwent batch reactor pyrolysis at 340°C and 380°C, resulting in production of liquid smoke (grade 3), charcoal, and tar. This liquid smoke was then distilled at 190°C to produce grade 1 liquid smoke, which was used to preserve mackerel. The preservation process was conducted by soaking the mackerel samples in liquid smoke at 0.5, 1, 2, and 3% concentration levels followed by observations every 6 hours. Tests to determine the total volatile base nitrogen (TVB-N) content, antibacterial quality of the liquid smoke and organoleptic quality of the fish were conducted in order to assess the preservation properties of the liquid smoke. Results: Tests on the antibacterial effects showed that the liquid smoke inhibited the growth of Escherichia coli and Staphylococcus aureus on fish even at low concentrations. At 54 hours, the TVB-N values remained below 30 mg nitrogen/g, indicating that the fish was still safe for human consumption. Results from the organoleptic tests showed that the concentration of liquid smoke influenced the preservation effects. Conclusions: At a concentration of 2–3%, the fish samples possessed acceptable flavor, taste, color and texture for up to 48 hours of soaking. However, the best conditions were obtained with a 3% concentration of liquid smoke (produced with 340°C pyrolysis), as the fish was still considered acceptable for up to 42 hours.
Twitter en tiempos electorales. Una revisión de #ColombiaDecide
Authors: Briceño Romero Ysabel Cristina , Calderón-Benavides Liliana , Manrique Johana Andrea , Camila Gélvez Salazar 
Published: July 2019

El siguiente artículo resume los resultados de una revisión de la etiqueta #ColombiaDecide en la red social Twitter, promovida por un medio de comunicación nacional en el contexto de las elecciones regionales de octubre de 2015. El estudio buscó analizar: 1) la tendencia de usuarios influyentes, según la noción de autoridad o liderazgo que califica a algunos actores sociales para informar, en los cuales la gente confía para reproducir sus mensajes; y 2) la tendencia de inclusión de usuarios en las conversaciones derivadas de Twitter. Los indicadores en esta revisión fueron: los mensajes con más rt (retuits) y los usuarios con más menciones (@) en el contenido derivado de la etiqueta analizada. Se realizó una cualificación de los usuarios destacados en ambos análisis, a partir de la revisión de 8039 tuits, de los cuales 4325 mensajes fueron replicados (rt) y 3527 tuvieron menciones (@). Igualmente, se efectuó una clasificación de los usuarios más destacados en las tendencias analizadas, según el perfil de las cuentas expresadas en la ‘bio’ de cada uno. Los resultados asoman que, aunque Twitter permite espacio para actores emergentes, aun los medios y periodistas se mantienen como líderes en los que los usuarios siguen confiando para reproducir contenido en el caso de una etiqueta que demanda información sobre resultados electorales; además, nos acercamos a captar una relación entre la tendencia de inclusión de candidatos electorales en las conversaciones derivadas de Twitter y los resultados de votación, para el caso de Bogotá.
Microwave Drying of Pitaya (Hylocereus) Peel and the Effects Compared with Hot-Air and Freeze-drying
Authors: Chew Ying Ming , King V. An-Erl 
Published: July 2019

Abstract. Microwave drying (MD) of pitaya peel was performed at 75, 225, 375, 525, and 750 W. The drying effects on the effective moisture diffusivity (De), total polyphenol content (TPC), betalain content, DPPH scavenging ability, and rehydration abilities of pitaya peel were examined. The data were compared with hot-air drying (HD) at 100°C for 4 h and freeze-drying (FD) for 24 h. The results showed that the MD kinetics of pitaya peel fit Fick’s law and the Arrhenius equation with an activation energy (Ea) of 34.08 W g-1. The De values of MD, which ranged from 2.35E-07 m2 s-1 (at 75 W) to 5.56E-06 m2 s-1 (at 750 W), indicated that the effectiveness of MD was appreciably higher than that of HD (2.44E-08 m2 s-1) and FD (4.43E-09 m2 s-1). Although MD resulted in decreased betacyanin (9.31 mg L-1 extract) and betaxanthin (6.58 mg L-1 extract) contents, the DPPH inhibition of pitaya peel remained at 75% due to an increase in TPC (115 mg GAE per 100 FW). MD of pitaya peel can also provide higher rehydration ability than HD and was comparable to FD. This study concludes that MD of pitaya peel was highly effective while maintaining high levels of TPC and DPPH inhibition. Keywords: Arrhenius equation, Effective moisture diffusivity, Fick’s law, Microwave drying, Pitaya peel.
Aspectos clínicos e epidemiológicos da introdução do vírus Chikungunya em Sergipe
Authors: Jesus Carlos Jivago Santos de , Santos Daiane Andrade , Góes Marco Aurélio de Oliveira 
Published: July 2019

Introdução: A Febre do Chikungunya é uma enfermidade febril aguda emergente que acarreta alta morbidade. Objetivo: Este estudo objetiva descrever os aspectos clínicos e epidemiológicos da introdução do Vírus Chikungunya (CHIKV)em Sergipe. Métodos: Trata-se de um estudo ecológico, com dados secundários do Sistema Nacional de Agravos de Notificação (SINAN) e do Laboratório Central de Sergipe (LACEN/SE), entre 2015-2017. Estudou-se variáveis sociodemográficas e clínicas dos casos confirmados de Chikungunya residentes no estado de Sergipe. Os dados foram tabulados pelo TABWIN e exportados para o Excel® 2016, para análise estatística utilizou-se o OpenEpi e teste qui-quadrado (p<0,05). Resultados: Demonstrou-se rápida expansão da enfermidade no território sergipano, atingindo nos 3 anos 82,7% dos municípios, com maior acometimento das microrregiões de saúde Grande Aracaju e Agreste Central. Dos 8806 casos confirmados verificou-se predominância em mulheres (60,79%), indivíduos de 20 a 59 anos (63,04%), pardos (27,46%), residentes em zona urbana (51,95%). Febre (83,8%), mialgia (77,9%) e artralgia (63,1%) estão entre os sintomas com maior frequência. Conclusão: O CHIKV apresenta grande potencial de disseminação no território e sua sintomatologia pode ser confundida com outros quadros infecciosos. Faz-se necessário o aprofundamentodo conhecimento sobre os diversos aspectos envolvidos no controle, diagnóstico e manejo clínico.
Reviews
Authors: Demaine Krystal , Weixiao Li , Rubin Rebecca , Elliott-Graves Leonie 
Published: July 2019

Rise Up! The Evolution and Revolution of Expressive Arts: Report on the 13th Biannual International Expressive Arts Therapy (IEATA) Conference, California, 28 February-3 March 2019
Rainbow of Creative Arts: International Summit of Creative Arts for Therapy and Education, Beijing, China, 9–10 March 2019
Art Therapy with Students at Risk: Fostering Resilience and Growth Through Self-Expression, Stella A. Stepney (2017) Springfield: Charles C Thomas Publisher Ltd., 309 pp., ISBN 978-0-39809-161-3, p/bk, $44.95
Combining the Creative Therapies with Technology: Using Social Media and Online Counseling to Treat Clients, Stephanie L. Brooke (ed.) (2017) Springfield: Charles C. Thomas Publishers Ltd, 311 pp., ISBN 978-0-39809-180-4, p/bk, $49.95
Reviews
Authors: Martinez Nicolas , Curtis Neal 
Published: July 2019

Why Comics? From Underground to Everywhere, Hillary Chute (2017) New York: Harper, 464 pp., ISBN 978-0-06247-680-7, h/bk, US$40
EC Comics: Race, Shock and Social Protest, Qiana Whitted (2019) New Brunswick: Rutgers University Press, 181 pp., ISBN 978-0-81356-631-3, p/bk, £25.50
Learning Resources by Environment sebagai Visualisasi Manajemen Sarana Prasarana Pendidikan di MIN Jejeran Bantul
Authors: Nadhiroh Siti , Jannah Rina Roudhotul 
Published: July 2019

This research based development and progress educational world wanted increase power creativeness and innovation from educators today. Visualize of educator’s credibility competence not only seen from the speed finish lessons. But, which the process optimize management of facilities and infrastructures, so as create learning resources by environment of school. The research is the qualitative study by taking background in MIN Jejeran Bantul Yogyakarta. The research results show that management of facilities and infrastructures includes activities of planning, pengiventarisan, the use of, maintenance, the removal of, and accountability also improve educator’s creativeness and enrich scientific who can be integrated to learning would also take morality school tuition to better understand in concrete terms and protecting the environment around.
The Role of Energy in a Real Business Cycle Model with an Endogenous Capital Utilization Rate in a Government Sector: Lessons from Bulgaria (1999–2016)
Authors: Vasilev Aleksandar 
Published: July 2019

Abstract
We introduce a pro-cyclical endogenous utilization rate of physical capital stock into a real business cycle model augmented with a government sector in detail. We calibrate the model to Bulgarian data for the period following the introduction of the currency board arrangement (1999–2016). We investigate the quantitative importance of the endogenous depreciation rate and the capital utilization mechanism working through the use of energy for cyclical fluctuations in Bulgaria. In particular, a positive shock to energy prices in the model works like a negative technological shock. Allowing for variations in factor utilization and the presence of energy as a factor of production improves the model performance against data, and in addition this extended setup dominates the standard RBC model framework with constant depreciation and a fixed utilization rate of physical capital (e.g., Vasilev (2009)).