bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative Monitoring with Cortical Estimulation
Authors: Sato Henry Koiti , Coelho Neto Maurício , Da Silva Jr Erasmo Barros , Da Silva Junior Luis Fernando Moura , Ramina Ricardo 
Published: April 2019

Introduction: Resection of gliomas in eloquent areas such as motor and supplementary motor areas has always been a main challenge for the surgeon due to the risk of severe neurological sequelae. An important tool used during the procedure to avoid postoperative deficits is the intraoperative cortical stimulation of eloquent areas as a safe option of functional area mapping. Methods: In this study, authors examined 50 patients with gliomas located in the motor and supplementary motor area that have undergone surgery with cortical stimulation, using clinical assessment of muscle strength in the pre- and immediate postoperative assessments and three months after surgery as parameters. Results: There was significant difference (p<0.001) between the preoperative and immediate postoperative assessments regarding the occurrence of severe neurological deficit, demonstrating a worsening of the neurological status after surgery. Concerning the comparison between the immediate postoperative period and the assessment performed three months after surgery, it was observed that all the patients who had severe deficit (11 cases) improved (p<0.001). No statistical difference was found between the malignancy grade and the evolution of the neurological deficit in the assessments performed in the three evaluated periods. Conclusion: In the immediate postoperative period following surgical resection of glial tumors in the motor and supplementary motor areas with intraoperative cortical monitoring, most patients have significant alterations in their muscle strength. However, three months after surgery there was significant improvement of these neurological deficits and no patient had severe sequelae.
Perfuração Intestinal como uma Rara Complicação da Derivação Ventrículo-Peritoneal
Authors: De Sousa Camila Moura , Lopes Janine Lemos de Melo Lobo Jofili , Braga Francisca Das Chagas Sheyla Almeida Gomes , Araújo Elis Raquel Da Silva , Dias Jefferson Fonseca , Sousa Emerson Brandão , Brito Jose Nazareno Pearce de Oliveira , Tavares Cléciton Braga 
Published: April 2019

A derivação ventriculoperitoneal (DVP) é o método de tratamento mais utilizado para o controle da hidrocefalia. Suas complicações mais frequentes são mau funcionamento do sistema e infecções. Já a perfuração intestinal espontânea, provocada pelo deslocamento do cateter distal da DVP, é uma complicação incomum e a exteriorização do cateter distal pelo ânus ainda mais infrequente. Esse trabalho tem como objetivo realizar uma revisão narrativa da literatura indexada sobre esta rara complicação, descrevendo os sinais e sintomas, as formas de diagnóstico e tratamento. Vários mecanismos têm sido propostos para justificar essa complicação, tais como a rejeição do catéter pela parede colônica, a fragilidade das alças entéricas, a perfuração direta por um trocarte durante a inserção do catéter peritoneal, dentre outros. Trata-se de uma complicação geralmente assintomática. Na maioria dos casos é necessário exteriorizar a DVP ou extrair o shunt e, em situações selecionadas, laparotomias e fechamentosdas perfurações
Morning Glory Syndrome
Authors: Cohen Moysés Isaac , Da Silva Matos Cleomir , De Amorim Róbson Luiz Oliveira , Ferreira Wander Da Silva , Cohen Jacob Moysés , Cohen Marcos Jacob , Cohen Sabrina Veloso Avi , Martins Henrique Oliveira , Amaral do Couto Ingrid Soani , Souza Marcos Robert Da Silva , Santos Júnior Alcimar Lavareda da Silva 
Published: April 2019

Morning Glory Syndrome is a very rare condition. It is characterized by an enlarged and funnel-shaped optic disc excavated and is associated with other craniofacial anomalies such as hypertelorism, cleft lip, cleft palate, and basal encephalocele. CaseReport. A case of a 30 year-old man who came for neurosurgical evaluation after a magnetic resonance imaging (MRI) scan that showed spheno-ethmoidal encephalocele is reported. Conclusions. There is a high association between basal encephalocele,midface abnormalities and Morning Glory Syndrome. A neurosurgical, ophtalmological and endocrinological evaluation must always be done. The patients present with ophtalmic signs and/or strabismus or poor vision. An image study should always be performed to delineate the extent of the lesion and a complete hormone screening should be carried out to exclude pituitary deficiency.
Metástase Intramedular de Melanoma
Authors: Ruschel Leonardo Gilmone , De Carvalho Nick Dorneli , Ramina Ricardo 
Published: April 2019

Introdução: Metástases intramedulares compõem uma condição rara; o melanoma é a minoria destes casos e ainda carecem dados na literatura para melhor entendimento. Assim como outras lesões intramedulares apresentam-se clinicamente com sintomas compressivos da medula espinal. A ressonância magnética (RM) é considerada o melhor exame para sua identificação, e o melhor tratamento é a ressecção cirúrgica. Método: Foram relatados dois casos de metástase intramedular de melanoma e realizada uma revisão sistemática da literatura sobre o assunto. Discussão: A metástase intramedular por melanoma apresentam melhorsobrevida quando comparada a outros tumores primários. A maioria dos casos encontrados na literatura tem apresentação medular alta, assim como os dois casos relatados. Alguns sinais no exame de imagem têm ajudado na diferenciação entre o tumor primário e essas metástases. Em relação à histologia não foi estabelecido um tipo mais prevalente para essa metástase e nos casos que apresentamos a evolução clinica dos pacientes foi bastante distinta, o que nos levou a descrever sobre o assunto. Conclusão: A ressecção microcirúrgica aliada à neuromonitorizaçã o, visando a preservaçã o da qualidade de vida e funçã oneurológica, seguida de radiaçã o e/ou quimioterapia mostrou-se como o melhor tratamento em casos selecionados.
Disreflexia Autonômica em Lesado Medular
Authors: Pereira Carlos Umberto , Pereira Francisco De Assis , Oliveira Debora Moura da Paixão , Rabelo Nicollas Nunes 
Published: April 2019

A disreflexia autonômica é considerada uma emergência médica. É uma síndrome que ocorre em pacientes com traumatismo raquimedular (TRM) acima do nível da sexta vértebra torácica (T6). Ocorre entre 40% a 90% dos pacientes com TRM acimade T6. O diagnóstico é clínico e apresenta como principais sintomas cefaleia, sudorese e piloereção. Encontra-se associado a crise hipertensiva e bradicardia. Quando o diagnóstico ou tratamento é incorreto pode ocasionar consequências graves parao paciente. É importante reconhecer esta síndrome, principalmente nas emergências, onde seu diagnóstico tem sido pouco reconhecido, assim como, levar seu conhecimento aos familiares e cuidadores destes pacientes.
Schwannoma Esporádico do Nervo Troclear
Authors: Constanzo Felipe , Spadoni Mariana Basso , Peruffo Letícia Chaffin Barbosa , Ramina Ricardo 
Published: April 2019

Introdução: Os schwannomas intracranianos representam 8% dos tumores do compartimento craniano. Habitualmente se originam dos nervos vestibular, trigeminal ou facial. Os schwannomas do nervo troclear são entidades raras, com menos de100 casos na literatura, e 33% com confirmação histológica. Relato de Caso: Mulher de 32 anos, com história de três meses de parestesias dimidiadas à esquerda, sem diplopia ou outras queixas visuais. A ressonância magnética evidenciou lesão sólidocísticaocupando a cisterna ambiens e do ângulo pontocerebelar à direita. Foi submetida a ressecção microcirúrgica da lesão, confirmada histopatológicamente como schwannoma, e com identificação da origem na porção cisternal do nervo troclear. Após cirurgia, a paciente apresentou melhora completa dos sintomas pré-operatórios, sem novos déficits. Revisão da Literatura: Foram usadas as bases de dados on-line PubMed, MEDLINE e Web of Science, resultando em 94 pacientes com 95 schwannomas encontrados na literatura. Do total, 33% tinham confirmação histológica. 42% foram submetidos a cirurgia, 16% a radiocirurgia, e 42% não foram tratados. Ressecção completa da lesão foi obtida em 58% dos pacientes tratados cirurgicamente. Conclusão: Os schwannomas de nervo troclear são lesões raras que devem fazer parte do diagnóstico diferencial das lesões tumorais, que ocupam a cisterna do ângulo pontocerebelar.
Transient Bobbing Following Fourth Ventricle Decompression in an Epidermoid Tumor
Authors: Olijnyk Leonardo , Mesquita Jr Ademar , Cardoso Geniffer , Raupp Gustavo Dos Santos , Gomes Matheus Ferreira , Fernandes Matheus Vanzin , Spassim Alex , Da Silva Carlos Eduardo 
Published: April 2019

The ocular bobbing (OB) refers to a distinct pattern of spontaneous vertical eye movements that occurs in various diseases of the posterior fossa pathologies. We describe a case of 42-years-old female submitted to epidermoid tumor removal through a subocciptal approach, presenting an OB during the postoperative period.The clinical aspects of the ocular bobbing are reviewed and discussed. There are other presentations or etiologies for OB, therefore differential diagnosis should always be carefully considered.
Traumatismo Raquimedular por Arma Branca
Authors: Pereira Carlos Umberto , Barbosa Breno José Alencar Pires , Dezena Roberto Alexandre , Santos João Manoel Da Silva , Dos Santos Yves Glauber Silva , De Carvalho Jamerson Ademir Cantarelli , Resende Laise Oliveira 
Published: April 2019

Introdução: Traumatismo raquimedular (TRM) por arma branca é pouco relatado na literatura médica. Seu tratamento é controverso. Os autores apresentam uma série de casos, discutem seu tratamento e prognóstico. Métodos: No período de janeiro de 2009 a dezembro de 2013, foram analisados doze pacientes vítimas de TRM por arma branca, quanto ao gênero, idade, localização anatômica da lesão, quadro neurológico, exames de imagem, tratamento e sequelas. Resultados: Quanto ao gênero, foram dez vítimas do sexo masculino e duas do sexo feminino. As idades variaram entre 16 e 54 anos, com média de 28 anos. Houve predomínio da localização cervical com cinco casos, seguido de dorsal com quatro e lombar com três. A tomografia computadorizada foi o exame de eleição. Oito pacientes apresentavam déficit motor e os demais eram assintomáticos. Cinco pacientes foram submetidos à intervenção cirúrgica, sendo três para retirada do corpo estranho e em dois para correção da dura-máter. Cinco pacientes apresentaram sequelas: paresia em membros inferiores em três e de membros superiores em dois. Não houve óbitos. Conclusão: TRM por arma branca é menos frequente que por arma de fogo e a literatura relata melhor prognóstico naqueles casos, fato evidenciado em nossos pacientes. Antibioticoterapia sistêmica profilática e fisioterapia motora têm sido preconizadas de rotina com resultados excelentes.
Meduloblastomas
Authors: Krebs Cláudio Luiz Liess , Gluszczuk Paulo , Suarez Juan Marcos Mira , Gallo Pasqualle 
Published: April 2019

Os autores apresentam 17 casos de meduloblastomas operados no Serviço de Neurocirurgia do Hospital Cristo Redentor no período de 11 anos (1976-1986). Foi observada maior incidência em pacientes jovens (10 meses a 29 anos de idade) e no sexo masculino (2:1). Os sinais e sintomas mais comuns foram os relativos a hipertensão intracraniana (HIC) e distúbrios cerebelares, sendo que o intervalo de tempo médio entre o início da sintomatologia e a hospitalização foi de dois meses e meio. Todos os pacientes foram submetidos a uma craniectomia suboccipital em posição sentada, sendo a derivação ventrículo-peritoneal (DVP) realizada previamente em cinco casos. A mortalidade pós-operatória foi de 29,4%
Screening and evaluation of upland rice (Oryza sativa L.) varieties in inundated soil
Authors: Adigbo Sunday Ojo , Osadebay Philip Joseph , Iseghohi Innocent , Alarima Cornelius Idowu , Agbenin Nnennaya Ogechi , Odedina Joy Nwakaego , Fabunmi Thomas Oladeji 
Published: April 2019

Abstract
Poor germination and subsequent low grain yield of dry seeded upland rice in the existing anaerobic and short niche between lowland rice and dry season crops in the inland valley necessitate the screening of 19 rice varieties. The identification of vigorous growth and short duration upland rice variety in anaerobic condition would optimize this niche. The potted experiment was carried out in the screen house of the Department of Crop Science and Horticulture, Federal University Oye-Ekiti, Ikole campus in 2015 to screen and evaluate the performance of upland rice varieties in inundated soils with a view to selecting the suitable variety or varieties that will fit into the existing niche in the inland valley. The experiment was laid in a complete randomization design and replicated three times. The number of leaves, biomass and grain weight plant−1 of the varieties were significantly (P ≤ 0.05 %) different. The number of tillers observed in WAB 56-104, NERICA 4, NERICA 6, NERICA 3, NERICA 5, NERICA 10, NERICA 9, ARICA 4 NERICA 1, FARO 63, FARO 65 and NERICA 8 varieties were significantly (P < 0.05) lower than those of Igbemo varieties. The numbers of days to 50 % flowering of NERICA 1, NERICA 2, NERICA 10, NERICA 5, NERICA 9, NERICA 3, NERICA 7, NERICA 8, ARICA 4 and WAB 56-104 varieties were the lowest. Although Igbemo brown, Igbemo white varieties had the highest grain yields per plant, their maturity period exceeded the short period. Thus, NERICA 2 and NERICA 5 varieties which had lower number of days to flowering could be considered as candidate varieties that can be optimized in the niche in question.
Exploring morphological variation in tomato (Solanum lycopersicum): A combined study of disease resistance, genetic divergence and association of characters
Authors: Kouam Eric Bertrand , Dongmo Joseph Roger , Djeugap Joseph Fovo 
Published: April 2019

Abstract
Genetic variation of quantitative traits is a prevalent characteristic among cultivated tomato varieties. Twenty tomato genotypes comprising indigenous varieties and commercial cultivars, cultured in the Western Region of Cameroon were evaluated using fourteen quantitative traits for disease resistance, phenotypic divergence and heritability estimates. The experiment was carried out using a randomized completed blocks design with three replications. Data collections were disease characteristics, plant development features and yield attributes. The analysis of variance revealed significant variation among genotypes for all the experimental quantitative traits. Hybrid varieties had significantly more fruit yield (1066.00 g/plant), single fruit weight (57.28 g), fruit diameter (4.47 cm) and pericarp thickness (0.54 cm) compared to standard and indigenous varieties. These indigenous varieties were significantly more resistant to late blight, alternaria leaf spot and viral diseases. They also had significantly higher collar diameter (16.30 mm), number of primary branches per plant (8.45), number of fruit per plant (31.58) and plant height (88.33 cm) compared to standard and hybrid plants. The genotype local 2 was the third most productive (1576.39 g / plant) after Rio Semagri (1984.80 g/plant) and Sakato F1 (1691.69 g/plant). Heritability and genetic advance estimates were high for twelve of the fourteen studied quantitative traits. Fruit yield showed significant positive correlations with single fruit weight and number of fruit per plant. However, significant negative correlation was found between fruit yield and time to 50 % flowering, 50 % fruiting, 50 % maturity and viral disease. The first three and the first four components in the principal component analysis explained, respectively, 77.85 % and 88.38 % of the total variation observed among genotypes. The first component determined 41.42 % of the total variation, dominated by the collar diameter, the number of primary branches per plant and plant height. This study clearly indicated that indigenous varieties are the most disease resistant genotypes and are having substantial fruit yield (945.30 g/plant) similar to standard varieties and at a touching distance to hybrid cultivars.
Determinants of technical efficiency in duck production in southwest Nigeria
Authors: Baruwa Olayinka Isiaka , Tijani Akeem Abiade , Alimi Taiwo 
Published: April 2019

Abstract
The need to complement the supply of animal products with other sources of poultry necessitates exploring the potentials of domestic duck production. Studies conducted on indigenous ducks in Nigeria have paid less attention to the resource requirements and its determinants to duck production. This study therefore estimated technical efficiencies of domestic duck producers in South-western Nigeria, and identified some socio-economic factors, which influence them. A combination of purposive and random sampling was employed. Stochastic frontier production function approach using a translog production function was used to estimate the technical efficiencies of indigenous duck producers, while inefficiency model was used to determine the socio-economic factors affecting the technical efficiencies. The results showed that the level of technical efficiency ranged from 48% to 96% with a mean of 83.3%, which suggests that average duck output was 16.7% short of the maximum possible level. This implies that productive efficiency could still be improved using the subsisting resource base. The study concluded that mounting capacity building programmes for duck farmers generally, and availability of credit could increase the productivity of duck enterprise if monitored.
In vitro response of three contrasting cassava (Manihot esculenta Crantz) varieties to mannitol-induced drought stress
Authors: Jolayemi Okanlawon Lekan , Opabode Jelili Titilola , Badara Gueye 
Published: April 2019

Abstract

In vitro selection of drought-tolerant cassava varieties is essential for rapid breeding for drought tolerance. The objectives of this study were to determine the response of three contrasting cassava varieties to mannitol-induced drought stress to establish its suitability for in vitro screening and examine relationships among growth parameters. Plantlets were raised from nodal segments on Murashige and Skoog (MS) medium containing 0 (control), 5, 10, 15, 20, 25 and 30 g/l mannitol. Variety CH 140 had the highest survival of explants and frequency of root formation, while MV 99/0395 recorded the highest number of chlorotic leaves and the lowest survival of explants. The lowest numbers of leaves were produced at 25 and 30 g/l mannitol by the three varieties. In CH 140, the highest number of leaves was produced in medium free of mannitol, while the highest number of leaves was produced at 5 and 10 g/l mannitol in MV 99/0395 and TMS 01/1206, respectively. In TMS 01/1206, number of roots produced decreased as the concentration of mannitol in culture media increased, whereas in CH140, number of roots increased as the concentration of mannitol increased before decreasing; while in MV 99/0395, number of roots was not affected by an increase in mannitol concentration. As the concentration of mannitol in the culture media increased shoot height of plantlets decreased with a sharp decline at 20 mg/l mannitol. Concentration of mannitol and survival of explants had significant negative correlation with all parameters. However, frequency of root formation only had significant positive correlation with shoot length. The study concluded that differential responses were expressed by the three varieties to mannitol-induced drought stress and mannitol at 20 g/l concentration was a suitable in vitro drought inducing-agent for screening cassava varieties for drought tolerance.
A Comparison of Social Learning Systems: Crochet Alongs and Moocs
Authors: Williams Shirley , Highwood E.J. 
Published: April 2019

Abstract
Essentially social learning is a system where the learning occurs with and from others. Internet-based technologies have provided environments within which social learning can take place among very large groups covering various topics, ranging from academic to leisure.
In general MOOCs are academic-related courses offered by educational institutions, following a model of formal education, however they also take advantage of the concept of social learning, encouraging participants to learn together and from each other.
Crochet Alongs (CALs) are non-formal courses offered outside educational institutions. CALs give crocheters the opportunity to learn more about their craft within an Internet-based social learning system, while working independently on their own instantiation of a pattern released at intervals. Participants offer support to each other via social media, sometimes seeking help in overcoming problems and other times just to share success.
There is a considerable body of research into the MOOC phenomena, there is no such body of research into CALs, or other Internet-based craft courses. There are a number of similarities between MOOCs and CALs with some CALs attracting thousands of participants to freely available online courses. Contrasting MOOCs and CALs offers educationalists to explore alternatives approaches to social learning.
Optimisation of Widefield Fluorescence Fret System for Studying Separate Molecule Interactions
Authors: Hippe Laura , Svirskis Šimons , Murovska Modra , Kālis Mārtiņš 
Published: April 2019

Abstract
The Förster Resonance Energy Transfer (FRET) method has wide application in modern science for studying protein–protein interactions and conformational changes. FRET allows to assess molecular interactions by measuring energy transfer between acceptor and donor fluorophores coupled to the molecule(s) of interest. The method demands high precision in experimental design, experimental settings and correct data interpretation. Therefore, we tested several parameters to estimate FRET measurement accuracy in our Nikon wide-field fluorescence FRET system. The experiments were performed in a HEK-293 cell line transfected with DNA constructs expressing Calcium Release-Activated Channel (CRAC) subunits STIM1 and ORAI1 coupled to donor fluorophore Cyan Fluorescent Protein (CFP) and acceptor fluorophore Yellow Fluorescent Protein (YFP), respectively. Exposure time and approach of data analysis varied throughout experiments in order to optimise FRET data quality. Dependence of FRETeff values on measurement quality and donor/acceptor fluorophore ratio in the cells was estimated. We demonstrated that, using the wide-field fluorescence FRET system, minimising the exposure of fluorophores before measurement using neutral density (ND) filters considerably minimises undesirable photo-bleaching of the fluorophores. There was a strong correlation between the CFP/YFP ratio in the cells and the observed FRET level, suggesting that only cells with certain donor/acceptor ratio might be comparable. We also showed impact of FRET measurement quality, defined as accordance of FRET pixels to Gaussian distribution, on FRET artefacts. Knowledge obtained during our experiments may be important for approbating similar wide-field fluorescence FRET systems to study two separate molecule interactions and for understanding the correct setup of the experiments and data interpretation.