bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acquiring Feedback from Students in Co‐Taught Classes
Authors: King‐Sears Margaret E. , Brawand Anne , Johnson Todd M. 
Published: October 2019

AbstractAcquiring feedback from students with and without disabilities about their experiences in co‐taught settings can provide valuable information to co‐teachers. In this article, informal surveys, interviews, and illustrations, derived from research, are described for co‐teachers to acquire feedback from students. Examples of queries and response formats are provided. Emphasis is also on co‐teachers using students’ feedback to maintain effective practices and make instructional refinements.
Population‐based interventions addressing food insecurity in Australia: A systematic scoping review
Authors: Yii Vivien , Palermo Claire , Kleve Sue 
Published: October 2019

AbstractAimFood insecurity (FI) is a critical public health issue in Australia. Population‐based interventions aiming to address the socio‐ecological determinants of FI are critical for relieving and preventing it. This review aimed to map and summarise the characteristics of population‐based interventions addressing household and/or community FI in Australia.MethodsA systematic scoping review was undertaken. Five databases, selected for range and relevance to FI in Australia (“CINAHL plus”, “Ovid MEDLINE”, “Sociological Abstracts”, “Australian Public Affairs Information Service”, and “Rural and Remote Health”) were searched in May 2018 using the terms and relevant synonyms “FI” and “interventions”. In addition a systematic grey literature search using multiple Google searches was undertaken. Data synthesis included categorisation and counting intervention type. Interventions were defined and charted by influence of at least one dimension of food security and impact on the socioeconomic, cultural and environmental conditions.ResultsA total of 3565 published and grey literature records were identified, with the final 60 records describing 98 interventions. Few national interventions were identified, with approaches predominantly in Victoria, Northern Territory and Tasmania. Determinants related to living and working environments, food availability and food utilisation were most frequently addressed. Interventions addressing the key determinant of FI economic access were limited. A number of interventions did not appear to be associated with rigorous evaluation.ConclusionsWhile there is evidence of population responses to FI in Australia, the effectiveness of these remains limited. Importantly there is a lack of coordinated and coherent national responses that address the range of FI determinants.
The effect of different anthropogenic disturbances on litterfall of a dominant pioneer rain forest tree in Gabon
Authors: Midoko Iponga Donald , Mpikou Rykielle Grace J. , Loumeto Joël , Picard Nicolas 
Published: October 2019

AbstractTropical rain forests worldwide are affected by anthropogenic disturbances, and secondary forests that develop afterwards are often dominated by pioneer tree species, but the consequences of different anthropogenic disturbances on nutrient cycling are poorly understood. Because most nutrient cycling in tropical rain forests occurs through litterfall and in the soil organic layer, we measured litterfall of a widespread and dominant pioneer tree, okoume (Aucoumea klaineana, Burseraceae) in Gabon, in one forest previously disturbed by logging and in another by agriculture. Litterfall of okoume trees, measured over 14 months, was 18.2 Mg ha−1 year−1in the formerly logged forest, which was 72.6% greater than in the forest more recently disturbed by agriculture (10.6 Mg ha−1 year−1). Litter decomposition rates were more rapid in the formerly logged forest, and this may explain why litter thickness was 32% lower in the formerly logged forest, despite the greater litterfall within it. Our results highlight that two widespread anthropogenic disturbances in Gabonese rain forests have significantly different consequences on litterfall of a dominant tree and therefore are likely to have different effects on nutrient cycling and forest ecosystem function.
Dupilumab is very effective in a large cohort of difficult‐to‐treat adult atopic dermatitis patients: First clinical and biomarker results from the BioDay registry
Authors: Ariëns Lieneke F. M. , van der Schaft Jorien , Bakker Daphne S. , Balak Deepak , Romeijn Margreet L. E. , Kouwenhoven Tessa , Kamsteeg Marijke , Giovannone Barbara , Drylewicz Julia , van Amerongen Cynthia Catalina Aurora , Delemarre Evelien M. , Knol Edward F. , van Wijk Femke , Nierkens Stefan , Thijs Judith L. , Schuttelaar Marie L. A. , de Bruin‐Weller Marjolein S. 
Published: October 2019

AbstractIntroductionDupilumab has recently been approved for the treatment of moderate to severe atopic dermatitis (AD) in adults. Daily practice data on dupilumab treatment are scarce.ObjectiveTo study the effect of 16‐week treatment with dupilumab on clinical response and serum biomarkers in adult patients with moderate‐severe AD in daily practice.MethodsData were extracted from the BioDay registry, a prospective multicenter registry. Sixteen‐week clinical effectiveness of dupilumab was expressed as number of patients achieving EASI‐50 (Eczema Area and Severity Index) or EASI‐75, as well as patient‐reported outcomes measures (Patient‐Oriented Eczema Measure, Dermatology Life Quality Index, Numeric Rating Scale pruritus). Twenty‐one biomarkers were measured in patients treated with dupilumab without concomitant use of oral immunosuppressive drugs at five different time points (baseline, 4, 8, 12, and 16 weeks).ResultsIn total, 138 patients treated with dupilumab in daily practice were included. This cohort consisted of patients with very difficult‐to‐treat AD, including 84 (61%) patients who failed treatment on ≥2 immunosuppressive drugs. At week 16, the mean percent change in EASI score was 73%. The EASI‐50 and EASI‐75 were achieved by 114 (86%) and 82 (62%) patients after 16 weeks of treatment. The most reported side effect was conjunctivitis, occurring in 47 (34%) patients. During dupilumab treatment, disease severity‐related serum biomarkers (TARC, PARC, periostin, and IL‐22), eotaxin‐1, and eotaxin‐3 significantly decreased.ConclusionTreatment with dupilumab significantly improved disease severity and decreased severity‐related serum biomarkers in patients with very difficult‐to‐treat AD in a daily practice setting.
Letter: should we delay surgery, or stop anti‐TNF therapy prior to elective surgical procedures in Crohn’s disease patients receiving anti‐TNF agents? Authors’ reply
Authors: Lin Yang‐Sheng , Chen Ming‐Jen , Lin Wei‐Chen , Wang Yuan‐Hung , Chen Chiehfeng 
Published: October 2019

LINKED CONTENTThis article is linked to Line et al and Yamamoto and Kotze papers. To view these articles, visit https://doi.org/10.1111/apt.15184 and https://doi.org/10.1111/apt.15450.
The association of age with the clinicopathological characteristics and prognosis of colorectal cancer: a UK single‐centre retrospective study
Authors: Anele C. C. , Askari A. , Navaratne L. , Patel K. , Jenkin J. T. , Faiz O. D. , Latchford A. 
Published: October 2019

AbstractIntroductionColorectal cancer (CRC) is uncommon in patients under the age of 40 years and its association with poor histological features and survival is uncertain. This study aimed to evaluate age‐related differences in clinicopathological features and prognosis in patients diagnosed with CRC.MethodA single‐centre retrospective review of all patients diagnosed with CRC between 2004 and 2013 was performed. Patients were stratified into three age groups: (1) 18–40 years, (2) 41–60 years and (3)> 60 years. Clinicopathological characteristics and outcomes were compared between the three groups.ResultsA total of 1328 patients were included, of whom 57.2% were men. There were 28 (2.1%) patients in group 1, 287 (21.6%) in group 2 and 1013 (76.3%) in group 3. Group 1 had the highest proportion of rectal tumours (57.1% in group 1, 50.2% in group 2 and 31.9% in group 3; P < 0.001). Tumour histology and disease stage were comparable between the groups. Group 1 had significantly worse disease‐free survival (DFS) than the two older groups (44%, 78% and 77%, respectively; P = 0.022). Multivariate analysis demonstrated that age was not an independent prognostic factor whereas Stage III disease [hazard ratio (HR) 4.42; 95% CI 2.81–6.94; P < 0.001] and neoadjuvant chemotherapy (HR 1.65; 95% CI 1.06–2.58; P = 0.026) were associated with increased risk of recurrence.ConclusionPatients under the age of 40 are more likely to present with rectal cancer and have comparable histological features than the older groups. Despite higher rates of adjuvant and neoadjuvant treatment, the young group were found to have worse DFS.
Mechanical and electromechanical properties of piezoelectric ceramic fibers drawn by the alginate gelation method
Authors: Mensur‐Alkoy Ebru , Kaya Mustafa Yunus , Sarı Huseyin Alptekin , Pekel Ozan , Olukkent Recep , Tur Yahya K. , Sebastian Tutu , Clemens Frank J. , Alkoy Sedat 
Published: October 2019

AbstractPiezoelectric ceramic fibers are widely used in piezocomposite devices. The various methods that are used to draw ceramic fibers differ in the way the fiber form is obtained, which in return closely affects the density, uniformity and the properties of the fibers that are obtained at the end. In this study, the processing‐property relationship in the piezoceramic fibers drawn using the alginate gelation method is investigated, with a focus on the mechanical and electrical properties of individual fibers. Fibers with a Weibull strength of 65.3 MPa, remanent polarization of 22 μC/cm2 and a total bipolar field induced strain of 0.25% under an electric field of 2.5 kV/mm, piezoelectric coefficient of 300 pm/V and dielectric constant of 3323 were produced. 1‐3 piezocomposite devices prepared from these fibers had a 6 dB higher free‐field voltage sensitivity and a 50% wider bandwidth compared to a solid disk transducer of the same dimensions.
Relaciones laborales y medidas de ajuste frente a la crisis. Análisis microestadístico comparativo de Francia y Gran Bretaña
Authors: AMOSSÉ Thomas , ASKENAZY Philippe , CHEVALIER Martin , ERHEL Christine , PETIT Héloïse , REBÉRIOUX Antoine 
Published: October 2019

ResumenEn este estudio comparativo, los autores analizan los vínculos entre las relaciones laborales y los ajustes salariales o de plantilla tras la crisis de 2007–2008, a partir de dos encuestas comparables sobre empresas de Gran Bretaña (WERS) y de Francia (REPONSE) en 2010–2012. Pese a las diferencias contextuales (composición del tejido productivo, circunstancias temporales e intensidad de la crisis), los vínculos entre las relaciones laborales y las estrategias de ajuste son parecidos (la presencia sindical no logra evitar los ajustes). Por lo tanto, la diferenciación de los sistemas de relaciones laborales no permite explicar las divergencias entre las modalidades de ajuste a nivel macroeconómico.
El efecto de la polarización del mercado de trabajo sobre la inserción laboral de los estudiantes universitarios en la República de Corea. Repercusiones en el desempleo juvenil
Authors: CHUNG Sungyup 
Published: October 2019

ResumenSe estima el efecto del entorno del mercado de trabajo y de las variables macroeconómicas sobre las decisiones y los indicadores laborales de los estudiantes universitarios en la República de Corea, según datos de la encuesta sobre movilidad laboral de los graduados para 2005–2013. Los resultados indican que la polarización del mercado de trabajo, medida con el índice de polarización de Chung y Jung (2016), incide significativamente en el desempleo nominal y encubierto (por la prolongación de la etapa estudiantil y el traslado de universidad) de los universitarios. Se concluye que la estructura del mercado de trabajo es un elemento fundamental para entender el desempleo juvenil.
Alopecia totalis and universalis long‐term outcomes: a review
Authors: Burroway B. , Griggs J. , Tosti A. 
Published: October 2019

AbstractAlopecia totalis (AT) and universalis (AU) represent the most severe subtypes of alopecia areata with more dramatic features and worse prognosis. The goal of this review is to identify all studies with long‐term prognostic data on patients with AT and AU and provide a long‐term outcome estimate. The PubMed database was queried to identify all articles discussing the long‐term prognosis of AT and AU. A total of nine articles discussing long‐term recovery rates of AT and AU were identified. The articles described 689 (162 = AT, 245 = AU, 282 = not specified) total patients. Six of the nine studies identified complete recovery as a potential end point in a total of 375 (39 = AT, 75 = AU, 261 = not specified) patients. According to these studies 8.5% (32/375) of AT and AU patients achieved complete recovery. A larger proportion of patients will obtain at least transient recovery periods of partial or total hair regrowth. The poor long‐term outcomes of AT and AU may cause patients to lose hope with treatment. Response to treatment is often unpredictable, and physicians should be aware of the prognosis and its effects in order to properly counsel patients.
Resistance to Streptococcus iniae and its genetic associations with traits of economic importance in Asian seabass (Lates calcarifer)
Authors: Van Khang Pham , Van Nha Vo , Nguyen Nguyen Hong 
Published: October 2019

AbstractStreptococcus iniae is one of the most serious aquatic pathogens, causing significant economic losses in marine and freshwater species, including Asian seabass (Lates calcarifer). Controlling this gram‐positive bacterial pathogen has been an issue in aquaculture systems, due to the combined effects of aquaculture intensification and climatic impacts. To date, there have not been any genetic parameter estimates for S. iniae resistance in Asian seabass. The main aim of this study was to examine genetic variation in S. iniae resistance and its genetic correlations with growth and cannibalism in Asian seabass families produced from a breeding programme for high growth in 2016 and 2017. The study included a total of 5,835 individual fish that were offspring of 41 sires and 60 dams (31 half‐sib and 34 full‐sib families). The experimental fish were challenged by intraperitoneal injection with a volume containing 105 CFU (colony‐forming unit)/fish. Resistance to S. iniae was measured as survival rate at 6 hr, 3, 5, 7, 10 and 15 days post‐challenge test. There were significant variations in S. iniae resistance among families at different observation periods (ranging from 24.4% to 80%). Restricted maximum‐likelihood method and mixed model analysis were applied to estimate heritability for S. iniae resistance. The heritability for S. iniae resistance ranged from 7% to 18% across different statistical models used. The common full‐sib effects accounted for 0.1%–2% of the total variation in resistance to S. iniae. Genetic correlations of the S. iniae resistance at 6 hr and 3 days with later post‐challenge test periods were low to moderate. However, these estimates for S. iniae resistance between successive measurement times (5, 7, 10 and 15 days) were high and close to 1. The genetic correlations of resistance with body weights at 180, 270 and 360 days post‐hatch were not significant as well with cannibalism. It is concluded that there is substantial additive genetic variation in resistance to S. iniae, suggesting there is potential for genetic improvement of Asian seabass for resistance to S. iniae through selective breeding.
Benefits of an advanced quantitative precipitation information system
Authors: Johnson Lynn E. , Cifelli Robert , White Allen 
Published: October 2019

AbstractA reconnaissance‐level regional resource accounting approach was applied to quantify benefits associated with an advanced quantitative precipitation information (AQPI) system being developed for the San Francisco Bay area. The AQPI system would provide incrementally higher resolution monitoring of rainfall events and longer lead‐time forecasts compared to current practice. AQPI system costs were estimated to have initial costs of $66 M and $3.3 M annual operation and maintenance; these translate to a present value cost (at 10 years and 6%) of $90 M. Benefits were associated with avoided flood damages, increasing water supplies, and enhancement of ecological, recreational, and transportation services. Total incremental benefits are estimated to be $61 M/year. Taken by category about 48% of the benefits are for flood damage mitigation ($29 M/year), with water supply (32%, $19.5 M/year), ecosystem (3.3%, $2 M/year), recreation (7.6%, $4.6 M/year), and transportation (9.5%, $5.8 M/year). These translate to a present value benefit of $449 M which computes to a base‐level B/C ratio of 5 to 1. Sensitivity analysis indicates a range of B/C up to 10 and down to 2. Given that most of the benefits are dependent on appropriate actions by hazards and water management agencies and citizens, then the AQPI project development involves outreach and training to maximize responses.
Dedicated to the Mission: Strategies US Department of Veterans Affairs Home‐Based Primary Care Teams Apply to Keep Veterans at Home
Authors: Haverhals Leah M. , Manheim Chelsea , Gilman Carrie , Karuza Jurgis , Olsan Tobie , Edwards Samuel T. , Levy Cari R. , Gillespie Suzanne M. 
Published: October 2019

BACKGROUND/OBJECTIVESThe US Department of Veterans Affairs (VA) Home‐Based Primary Care (HBPC) Program provides interdisciplinary, long‐term primary care for frail, disabled, or chronically ill veterans. This research identifies strategies used by HBPC teams to support veterans in their homes, rather than in institutionalized care.DESIGNFocus groups and semistructured interviews were conducted with HBPC interdisciplinary team (IDT) members, including program directors, medical directors, and key staff, from September 2017 to March 2018. Field observations were gathered during visits to veterans’ homes and IDT meetings.SETTINGIn‐person site visits were conducted at eight HBPC Programs across the United States. Sites varied in location, setting, and primary care model.PARTICIPANTSA total of 105 HBPC professionals.MEASUREMENTQualitative thematic content analysis.RESULTSFour main strategies drive and support the shared mission of IDTs to support veterans at home: fostering frequent communication among IDT members, veterans, caregivers, and outside agencies; development of longitudinal, trusting, reliable relationships within IDTs and with veterans and caregivers; ongoing, consistent education for IDT members and veterans and caregivers; and collaboration within and outside IDTs. Adhering to this mission meant providing timely and efficient care that kept veterans in their homes and minimized the need for acute hospitalizations and nursing home placement.CONCLUSIONHBPC IDTs studied worked together across disciplines to effectively create a dedicated culture of caring for veterans, caregivers, and themselves, leading to keeping veterans at home. Focusing on the strategies identified in this research may be useful to achieve similar positive outcomes when caring for medically complex, homebound patients within and outside the VA. J Am Geriatr Soc 67:2511–2518, 2019
Wnt5a is involved in LOX‐1 and TLR4 induced host inflammatory response in peri‐implantitis
Authors: Zhang Qian , Liu Jie , Ma Lei , Bai Na , Xu Huirong 
Published: October 2019

AbstractBackground and objectivePeri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants, characterized by inflammation in the peri‐implant mucosa and subsequent progressive loss of supporting bone. Wnt5a is the activating ligand of the non‐canonical Wnt signaling pathways and plays important roles in leukocyte infiltration and cytokine/ chemokine production in inflammatory disorders. Previous studies showed that Wnt5a was significantly up‐regulated in gingival tissues of chronic and aggressive periodontitis. However, the roles and the regulatory mechanisms of Wnt5a in peri‐implantitis are not well known.MethodsThe expression of Wnt5a in gingival tissues collected from 8 healthy implant patients and 8 peri‐implantitis patients was analyzed by Western blotting and immunofluorescence. Porphyromonas gingivalis infected macrophages isolated from the peripheral blood of healthy volunteers were used as an in vitro cellular model of peri‐implantitis. Using neutralizing antibodies, inhibitors and siRNA, the production and roles of Wnt5a in peri‐implantitis were assessed by immunofluorescence, quantitative polymerase chain reaction (RT‐PCR) and Western blotting. Unpaired two‐tailed Student's t test was used to compare qRT‐PCR and Western blotting results. P ≤ .05 was considered statistically significant.ResultsWnt5a was highly expressed in the gingival tissues of peri‐implantitis patients. Compared to controls, Wnt5a increased in P gingivalis infected macrophages. Wnt5a production in response to P gingivalis infection was dependent on LOX‐1 and TLR4. Compared to controls, Wnt5a knockdown impaired IL‐1β, MCP‐1, and MMP2 production induced by P gingivalis infection.ConclusionOur results indicate that Wnt5a is involved in LOX‐1 and TLR4 induced inflammatory signature via inflammatory cytokines production in response to P gingivalis infection. These findings demonstrate that Wnt5a maybe an important component of the host immune response in peri‐implantitis.
Fragmentation reduces the importance of niche‐based factors relative to dispersal traits in structuring temperate forest understories
Authors: Sonnier Grégory , Johnson Sarah E. , Waller Donald M. 
Published: October 2019

AbstractAimThe relative importance of stochastic and deterministic niche processes can affect the assembly of communities in response to land use context and change. In this study, we quantified the relative importance of dispersal‐ vs niche‐based processes in structuring forest plant metacommunities and sought to understand how these processes have changed in these forests over the past 50 years.LocationWisconsin, USA.MethodsWe used plant understorey community survey data in both the 1950s and 2000s from 142 upland forest stands in southern and northern Wisconsin forests to relate compositional similarity to geographic and environmental distances among sites (reflecting dispersal and niche‐based processes, respectively). We then partitioned the variance to determine their relative importance over time. Finally, we classified species into three dispersal groups based on seed mass, dispersal mode, and plant height to assess how these affect community structure.ResultsBoth niche and dispersal processes influence the structure of Wisconsin's forest plant understories. Niche‐based processes related to environmental differences among sites dominate the mostly continuous northern upland forests. In contrast, dispersal processes dominate community assembly in the more fragmented southern upland forests. Dispersal processes increased in importance in both regions and especially in more fragmented southern upland forests over the past 50 years. We detected no differences among dispersal groups in how similarity decays with geographic distance.ConclusionsIn regions retaining heavy forest cover, niche‐based assembly still predominates while in areas with smaller scattered patches of forest, stochastic dispersal plays a greater role. Dispersal‐based processes increasingly dominate forest metacommunity dynamics in both regions.