bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les parents funambules : entre désir d’enfant et désir d’accueil, un équilibre à négocier dans la famille d’accueil régulière au Québec
Authors: Boyer Ariane , Noël Raphaële 
Published: May 2019

Cadre de la recherche : Chaque année au Québec, des milliers d’enfants sont pris en charge par la protection de la jeunesse suite à la compromission de leur sécurité ou de leur développement. Parmi les sujets qui ont choisi de les accueillir, les familles d’accueil régulières reçoivent les enfants pour une durée de temps variable et s’exposent ainsi à leur départ. Ils ne souhaitent pas d’emblée les adopter ou ne peuvent pas accéder à une reconnaissance légale d’un statut parental.
Objectifs : Cette recherche qualitative inductive vise à explorer les aspects affectifs et psychiques du vécu et de l’expérience des parents d’accueil.
Méthodologie : Des entretiens non directifs ont été effectués auprès de dix parents de familles d’accueil régulières québécoises. Chaque participant a été rencontré à deux reprises. Une analyse par catégories conceptualisantes a été appliquée à l’ensemble des transcriptions d’entretien. L’articulation des catégories est présentée dans un modèle intégrateur.
Résultats : Les participants présentent des trajectoires de vie dans lesquelles prédomine le don de soi. Ils se trouvent dans une position complexe de parent et de non-parent face aux enfants qu’ils accueillent. De plus, ils soulignent la difficulté d’établir un lien de proximité avec des enfants qui peuvent partir à tout moment. Différents défis relatifs à la relation avec l’institution sont également soulevés. Les résultats sont discutés à partir de la catégorie intégratrice des parents funambules, ainsi que du concept de désir d’accueil.
Conclusions : Les résultats mettent à jour des caractéristiques ayant mené des couples vers l’accueil d’enfants en difficulté et décrivent la complexité de la position de parent d’accueil. Ils soulèvent également une certaine précarité inhérente à cette position qui résulte notamment d’une oscillation entre désir d’accueil et désir d’enfant, d’où l’appellation de parent funambule.
Contributions : La présente étude permet de contribuer aux connaissances concernant les aspects affectifs et psychiques de l’expérience des parents d’accueil québécois. Elle soulève la nécessité de penser un accompagnement spécifique à ces enjeux.
Genetic variation and forensic efficiency of 30 indels for three ethnic groups in Guangxi: relationships with other populations
Authors: Du Weian , Feng Chunlei , Yao Ting , Xiao Cheng , Huang Hongyan , Wu Weibin , Zhu Linnan , Qiao Honghua , Liu Chao , Chen Ling 
Published: May 2019

AimIn this study, we used a series of diallelic genetic marker insertion/deletion polymorphism (indel) to investigate three populations of Yao, Kelao, and Zhuang groups in the Guangxi region of China and to evaluate their efficiency in forensic application.ResultNo deviations for all 30 loci were observed from the Hardy–Weinberg equilibrium after Bonferroni correction (p> 0.05/30 = 0.0017). The allele frequencies of the short allele (DIP-) for the above three populations were in the range of 0.0520–0.9480, 0.0950–0.8780, and 0.0850–0.915, respectively. The observed heterozygosity of the 30 loci for the three populations was in the ranges 0.0802–0.5802, 0.1908–0.6053, and 0.1400–0.5600, respectively. The cumulative power of exclusion and combined discrimination power for Yao, Kelao, and Zhuang groups were (0.9843 and 0.9999999999433), (0.9972 and 0.9999999999184), and (0.9845 and 0.9999999999608), respectively. The DA distance, principal component analysis, and cluster analysis indicated a clear regional distribution. In addition, Zhuang groups had close genetic relationships with the Yao and Kelao populations in the Guangxi region.ConclusionThis study indicated that the 30 loci were qualified for personal identification; moreover, they could be used as complementary genetic markers for paternity testing in forensic cases for the studied populations.
Prognostic factors and outcomes of early-stage small cell neuroendocrine carcinoma of the cervix: 37 cases from a single center
Authors: Zhang Dandan , Ma Xiaoxin 
Published: May 2019

Background
The objective of this study is to investigate small cell neuroendocrine carcinoma of the cervix (SCCC), using a retrospective clinicopathological characteristic and treatment approach.

Method
We retrospectively analyzed cases of early-stage SCCC, identified between 2006 and 2016, in women who received radical surgery and adjuvant chemotherapy with or without radiotherapy. Kaplan–Meier and one-way ANOVA analyses were performed.

Result
A total of 37 cases of SCCC are presented in this study, of which 21 had stage IB1 SCCC, 12 had stage IB2, 3 had stage IIA1, and 1 had stage IIA2. All patients were treated with radical surgery and adjuvant chemotherapy, specifically, 26 with radical surgery followed by adjuvant chemotherapy plus radiation and 11 with neoadjuvant chemotherapy (NACT) followed by radical surgery. After a median follow-up time of 27 months (range, 8–115 months), the 2-year and 5-year disease-free survival rate for all patients was 51.9% and 34.1%, respectively, and the overall survival rate was 60.3% and 38.6%, respectively. Univariate analysis showed that International Federation of Gynecology and Obstetrics (FIGO) stage and tumor size may be a predictor of a poor prognosis. NACT and adjuvant radiation did not improve survival over adjuvant chemotherapy alone but should not be a significant independent prognostic factor for survival.

Conclusion
Even in patients with early-stage SCCC, the prognosis is poor, although FIGO stage and tumor size may act as surrogate factors prognostic of survival.
Transcriptome analysis ofChelidonium majuselaiosomes and seeds provide insights into fatty acid biosynthesis
Authors: Wu Jiayue , Peng Linlin , Dong Shubin , Xia Xiaofei , Zhao Liangcheng 
Published: May 2019

BackgroundElaiosomes are specialized fleshy and edible seed appendages dispersed by ants. Lipids are the primary components of elaiosomes.Chelidonium majusis a well-known plant, the seeds of which are dispersed by ants. Previous studies have identified the presence of primary fatty acids in its elaiosomes and seeds. However, the molecular mechanisms underlying fatty acid biosynthesis in elaiosomes remain unknown.MethodsIn order to gain a comprehensive transcriptional profile of the elaiosomes and seeds ofC. majus, and understand the expression patterns of genes associated with fatty acid biosynthesis, four different developmental stages, including the flower-bud (Ch01), flowering (Ch02), young seed (Ch03), and mature seed (Ch04) stages, were chosen to perform whole-transcriptome profiling through the RNA-seq technology (Illumina NGS sequencing).ResultsA total of 63,064 unigenes were generated from 12 libraries. Of these, 7,323, 258, and 11,540 unigenes were annotated with 25 Cluster of Orthologous Groups, 43 Gene Ontology terms, and 373 Kyoto Encyclopedia of Genes and Genomes pathways, respectively. In addition, 322 genes were involved in lipid transport and metabolism, and 508 genes were involved in the lipid metabolism pathways. A total of 41 significantly differentially expressed genes (DEGs) involved in the lipid metabolism pathways were identified, most of which were upregulated in Ch03 compared to Ch02, indicating that fatty acid biosynthesis primarily occurs during the flowering to the young seed stages. Of the DEGs, acyl-ACP thioesterases, acyl carrier protein desaturase (DESA1), and malonyl CoA-ACP transacylase were involved in palmitic acid synthesis; stearoyl-CoA desaturase andDESA1were involved in oleic acid synthesis, and acyl-lipid omega-6 desaturase was involved in linoleic acid synthesis.
Physical and Mechanical Properties of Heat Treated Daniella oliveri (Africa Balsam Tree) Wood
Authors: Iyiola Ebenezer Adeyemi , Olufemi Babatola , Oyerinde Victoria Olubukola , Owoyemi J. M. , Samuel Ayanleye 
Published: May 2019

Aims: This work investigated the effect of thermal modification on some of the physical properties and mechanical properties of Daniella oliveri wood.
Study Design: The study design used for this experiment was 3 x4 Factorial experiment in Completely Randomized Design.
Place and Duration of Study: The study was conducted at the Federal University of Technology, Akure wood laboratory and the study lasted for 6 months.
Methodology: Wood samples were thermally treated at the temperature of 120, 140, 160 and 180°C, for different durations of 1, 1.5 and 2 hours in a muffle furnace. The planks were air-dried to reduce the moisture content and then machined into the required dimensions in the direction parallel to grain with a circular saw. Thirty-nine defect-free samples of dimensions 20 mm × 20 mm × 60 mm were prepared for dimensional stability and compression test, static bending tests and the hardness tests to make a total of 117 samples.
Results: The result showed that the average weight loss of the treated wood samples varied from 3.79% at 120°C for 1 hour to 7.51% at 180°C for 2 hours. The treatment led to reduction in density from 528 to 459 kg/m3 at 180°C for 2 hours. The heat treatment also led to reduction in water absorption and volumetric swelling of the treated samples. The mean value for Modulus of elasticity (MOE) ranges from 2.17x103 N/mm2 to 2.96 x 103 N/mm2 for the treated samples while the untreated was 2.22x103 N/mm2. Heat treatment brought about improvement in the maximum compressive strength and the Janka hardness parallel to the grain of wood samples. The value of compressive strength increased from 26.58 N/mm2 to 41.71 N/mm2 and hardness from 69.24 N to 75.5 N. It can therefore be concluded that thermal modification greatly enhanced the dimensional stability and mechanical properties of wood samples.
Internodular functional connectivity in heterotopia‐related epilepsy
Authors: Khoo Hui Ming , von Ellenrieder Nicolás , Zazubovits Natalja , Hall Jeffery A. , Dubeau François , Gotman Jean 
Published: May 2019

AbstractObjectiveA vast network involving the nodules and overlying cortices is believed to be responsible for the epileptogenicity in gray matter heterotopia with multiple nodules, which often associated with difficult‐to‐treat epilepsy. We sought to determine if functional magnetic resonance imaging (fMRI) could detect internodular functional connectivity (FC), and if this connectivity reflects an actual synchronized neuronal activity and partakes in epileptogenicity.MethodsWe studied 16 epilepsy patients with multiple heterotopic nodules; eight underwent subsequent intracerebral EEG. We examined the internodular FC using fMRI and its correspondence with internodular synchrony of intracerebral interictal activity. We then compared the spreading speed of ictal activity between connected and unconnected nodules; and the FC among possible combinations of nodule pairs in terms of their involvement at seizure onset.ResultsSeventy nodules were studied: 83% have significant connection to at least one other nodule. Among the 49 pairs studied with intracerebral EEG, (1) synchronized interictal activity is more prevalent in fMRI‐connected pairs (P < 0.05), (2) ictal activity spreads faster between connected pairs (P < 0.0001), and (3) stronger FC was observed between pairs in which both nodules were involved at seizure onset (P < 0.01).InterpretationfMRI could reliably and noninvasively detect the FC between heterotopic nodules. These functional connections correspond to the synchrony of interictal epileptic activity between the nodules and to the ability of nodules to generate synchronous seizure onsets or rapid seizure spread. These findings may help in understanding the complexity of the epileptogenic network in multiple heterotopic nodules and better targeting the likely epileptogenic nodules.
Information leakage in the Response Time‐Based Concealed Information Test
Authors: Lukács Gáspár , Ansorge Ulrich 
Published: May 2019

SummaryThe Response Time‐Based Concealed Information Test (RT‐CIT) can reveal when a person recognizes a relevant (probe) item among other, irrelevant items, based on comparatively slow responses to the probe item. For example, if a person is concealing his or her true identity, one can use the suspected identity details as probes, and other, random details as irrelevants. However, in our study, we show that even when participants are merely informed about such probes (i.e., the relevant identity details) before performing the RT‐CIT, their responses will also be slower to these details. Hence, it is more difficult to distinguish such innocent but pre‐informed persons from actually guilty persons. At the same time, we introduce a CIT version with familiarity‐related inducer stimuli, but with no targets, that elicits probe‐minus‐irrelevant RT differences only among guilty participants but not among informed innocent participants. Implications for the theory and the application of CITs are discussed.
Stable, High‐Sensitivity and Fast‐Response Photodetectors Based on Lead‐Free Cs2AgBiBr6 Double Perovskite Films
Authors: Yang Jie , Bao Chunxiong , Ning Weihua , Wu Bo , Ji Fuxiang , Yan Zhibo , Tao Youtian , Liu Jun‐Ming , Sum Tze Chien , Bai Sai , Wang Jianpu , Huang Wei , Zhang Wenjing , Gao Feng 
Published: May 2019

AbstractSolution‐processed metal halide perovskites (MHPs) have demonstrated great advances on achieving high‐performance photodetectors. However, the intrinsic material instability and the toxicity of lead still hinder the practical applications of MHPs‐based photodetectors. In this work, the first highly sensitive and fast‐response lead‐free perovskite photodetectors based on Cs2AgBiBr6 double perovskite films are demonstrated. A convenient solution method is developed to deposit high‐quality Cs2AgBiBr6 film with large grain sizes, low trap densities, and long charge carrier lifetimes. Incorporated within a photodiode device architecture comprised of optimized hole‐ and electron‐transporting layers, lead‐free perovskite photodetectors are achieved exhibiting a high detectivity of 3.29 × 1012 Jones, a large linear dynamic range of 193 dB, and a fast response time of ≈17 ns. All the key figures of merit of the devices are comparable with the reported best‐performing photodetectors based on lead halide perovskites. In addition, the resulting devices exhibit excellent thermal and environmental stability. The nonencapsulated devices show negligible degradation after thermal stressing at 150 °C and less than 5% degradation in the photoresponsivity after storage in ambient air for ≈2300 h. The results demonstrate the great potential of the lead‐free Cs2AgBiBr6 double perovskite in applications for environmentally friendly and high‐performance photodetectors.
Strategy for Controlling the Electrical Conductivity of Indium Tin Oxide (ITO) Nanobranches
Authors: Lee Dong Kyu , Choi Kyoung Soon , Lee Jaeyeong , Kim Youngho , Oh Sein , Shin Hojun , Jeon Cheolho , Yu Hak Ki 
Published: May 2019

AbstractThe electronic properties of indium tin oxide (ITO) nanobranches fabricated by electron beam evaporation are controlled using the following two methods: i) The growth direction of the rods and branches is controlled by an epitaxial relationship with a yttria‐stabilized zirconia substrate. The aligned growth of ITO nanobranches causes low sheet resistance because of the high density and good connectivity of the branches. ii) Heterojunction metal‐oxide nanoparticles are coated on the surface of the nanobranches to form a depletion region in the near surface for band bending. The morphology of the metal oxide also affects the electronic properties of the nanobranches. The sheet resistance of Fe2O3‐coated nanobranches (Fe2O3: film shape) increases linearly with the number of coatings. In the case of Mn2O3 (Mn2O3: nanoparticle shape), the sheet resistance is dramatically increased and saturated with the increase in the number of coatings.
Expansions and contractions of the FMR1 CGG repeat in 5,508 transmissions of normal, intermediate, and premutation alleles
Authors: Nolin Sarah L. , Glicksman Anne , Tortora Nicole , Allen Emily , Macpherson James , Mila Montserrat , Vianna‐Morgante Angela M. , Sherman Stephanie L. , Dobkin Carl , Latham Gary J. , Hadd Andrew G. 
Published: May 2019

AbstractInstability of the FMR1 repeat, commonly observed in transmissions of premutation alleles (55–200 repeats), is influenced by the size of the repeat, its internal structure and the sex of the transmitting parent. We assessed these three factors in unstable transmissions of 14/3,335 normal (~5 to 44 repeats), 54/293 intermediate (45–54 repeats), and 1561/1,880 premutation alleles. While most unstable transmissions led to expansions, contractions to smaller repeats were observed in all size classes. For normal alleles, instability was more frequent in paternal transmissions and in alleles with long 3′ uninterrupted repeat lengths. For premutation alleles, contractions also occurred more often in paternal than maternal transmissions and the frequency of paternal contractions increased linearly with repeat size. All paternal premutation allele contractions were transmitted as premutation alleles, but maternal premutation allele contractions were transmitted as premutation, intermediate, or normal alleles. The eight losses of AGG interruptions in the FMR1 repeat occurred exclusively in contractions of maternal premutation alleles. We propose a refined model of FMR1 repeat progression from normal to premutation size and suggest that most normal alleles without AGG interruptions are derived from contractions of maternal premutation alleles.
Isotopic equifinality and rethinking the diet of Australopithecus anamensis
Authors: Quinn Rhonda L. 
Published: May 2019

AbstractObjectivesAustralopithecus anamensis has comparable δ13Cenamel values to Ardipithecus ramidus, and both have been characterized as C3 feeders in open woodland habitats similar to “savanna” chimps. Unlike Ar. ramidus and “savanna” chimps, A. anamensis shows a derived dentognathic morphology for tough foods and a dental microwear pattern similar to the C3–C4‐mixed‐feeding A. afarensis. Here I test the hypothesis that changing the variables (ε*enamel‐diet, δ13CC3, δ13CC4 values) used to calculate the percentage of dietary C4 foods (%C4 diet) by 1–2‰ does not make a substantial difference for hominin diet reconstructions [van der Merwe, Masao, & Bamford, 2008, South African Journal of Science 104:153–155].Materials and MethodsI estimate vegetation structures for A. anamensis with pedogenic carbonate and faunal enamel δ13C values from the Pliocene Omo‐Turkana Basin (4.2–3.9 Ma). I recalculate A. anamensis' %C4 diet based on new body size‐dependent estimates of the ε*enamel‐diet value and alternative δ13CC3 and δ13CC4 values.ResultsThe Pliocene Omo‐Turkana Basin shows evidence for dietary resources with a wide range of δ13C values including canopy‐driven 13C depleted ground C3 foods. Alternative equation variables changed by 1–2‰ yield higher C4 estimates for A. anamensis (15–31%) than previously thought (0–10%). The choice of δ13CC3 and δ13CC4 values for estimating %C4 is not a perfunctory task and potentially explains the δ13C isotopic equifinality of A. anamensis and “savanna” chimps.DiscussionMy integrative diet model reconciles the carbon isotopic data with the dentognathic and microwear evidence of A. anamensis' diet and suggests that “savanna” chimps are not proper dietary analogs of A. anamensis. A foraging strategy across heterogeneous habitats of the Pliocene Omo‐Turkana Basin incorporating an array of 13C‐depleted and 13C‐enriched C3 foods and a portion of C4 resources may have served as one of the selective pressures for A. anamensis, the earliest habitual biped [van der Merwe et al., 2008, South African Journal of Science 104:153–155].
Those who died very young—Inferences from δ15N and δ13C in bone collagen and the absence of a neonatal line in enamel related to the possible onset of breastfeeding
Authors: Siebke Inga , Moghaddam Negahnaz , Cunningham Craig A. , Witzel Carsten , Lösch Sandra 
Published: May 2019

AbstractObjectivesStable isotope analysis has often been used in neonatal remains from archeological contexts to investigate the presence of a signal of breastfeeding and weaning in past populations. Tooth histology on the other hand might be used as an indicator of birth survival. This pilot study aimed to investigate the feasibility of using stable nitrogen (δ15N) and carbon (δ13C) isotope values from neonatal bone collagen to elucidate if values deviating from the adult female average could indicate breastfeeding and co‐occur with the presence of a neonatal line (NNL). The combination of these independent indicators might be useful in clarifying the fate of individuals who died around birth.Materials and MethodsBone collagen from 21 archeological human and animal specimens was extracted and analyzed via mass‐spectrometry for δ15N and δ13C. A verification of the stable isotope results was undertaken using tooth histology on three individuals who were investigated for the presence of a NNL as an indicator of live birth and short survival.ResultsThe biological age of the human samples varied between 8.5 lunar months (Lm) and 2 postnatal months (Pm) of age. All except one individual exhibited elevated δ15N values compared to the female average. The histological analyses revealed no NNL for this and two further individuals (n = 3).DiscussionThe results indicate that elevated nitrogen values of very young infants relative to a female average in archeological contexts are not necessarily associated with a breastfeeding onset signal, and therefore cannot be used exclusively as a proxy of birth survival. The elevation might be possible due to various reasons; one could be nutritional, in particular maternal stress during pregnancy or a metabolic disorder of mother and/or her child. In those cases, the evaluation of a NNL might reveal a false breastfeeding signal as seen for two individuals in our sample who have elevated nitrogen values despite the fact no NNL could be observed. Overall, our data support the growing awareness that bone collagen δ15N values of neonates/infants should not be used as a proxy for breastfeeding or birth survival on its own.