bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical features and treatment of patients with lung adenocarcinoma with bone marrow metastasis
Authors: Wang Di , Luo Yang , Shen Di , Yang Lin , Liu Hui-Ying , Che Yi-Qun 
Published: April 2019

Background: Bone marrow metastasis occurs in lung adenocarcinoma patients with a poor prognosis due to the late course and lack of definitive treatments, although reports on this are limited. This study analyzed the clinical manifestation, laboratory examination, treatment, and prognosis of patients with lung adenocarcinoma with bone marrow metastasis. Methods: All patients were confirmed to have bone marrow infiltration by bone marrow aspiration. The clinical data of 12 patients with lung adenocarcinoma with bone marrow metastasis were analyzed retrospectively. The prognostic factors were analyzed by Kaplan-Meier statistics. Results: The common biomarker abnormalities in 12 patients were elevated carcinoembryonic antigen in 12 cases (100%), elevated lactate dehydrogenase in 9 cases (75%), increased alkaline phosphatase and anemia in 8 cases each (66.7%), and thrombocytopenia in 4 cases (33.3%). After diagnosis of bone marrow metastasis, 5 patients were treated with platinum-based chemotherapy, 3 patients received chemotherapy and targeted drug tyrosine kinase inhibitor (TKI) therapy, 2 patients received simple TKI therapy, and 2 patients received only best supportive care (BSC) therapy. The median duration of survival after the diagnosis of bone marrow involvement was 422 days. The survival time of patients receiving TKI therapy after bone marrow metastasis was significantly better than that of patients receiving only BSC and chemotherapy (χ2=4.636, P=0.031). Conclusions: The survival period of patients with lung adenocarcinoma with bone marrow metastasis is short, and targeted drug TKI treatment can prolong the survival time for patients with EGFR mutation–carrying lung adenocarcinoma with bone marrow metastasis.
A RANZCP trainee’s experience of working with patients with an intellectual disability: a case series
Authors: Naveed Sheikh 
Published: April 2019

Objectives: This study aimed to highlight the interplay of intellectual disability and psychiatric presentation using a case series. Methods: A brief review of the current literature and an illustrative case series of five intellectually disabled patients with psychiatric patients whose diagnosis were clarified over time who presented with a psychiatric illness are provided. Results: The presence of intellectual disability often compounds the difficulty of establishment of mental-health diagnosis. Conclusions: More focus is required on training and skills development across mental-health services regarding the assessment of psychiatric disorders in people with an intellectual disability.
A Scoping Review of Contemporary Social Work Practice With Veterans
Authors: Bloeser Katharine J. , Bausman Margaret 
Published: April 2019

Objective: Social work served U.S. veterans and service members throughout its history as a profession. Social workers continue to support the physical and psychological health of veterans in both the public and private sectors. This scoping review sought to characterize the social work research on practice with veterans. Methods: Both academic sources and gray literature were reviewed. Results: A total of 536 items were reviewed to determine methodology, sample, social work’s role in the research, content area, and publication type. The largest category of research methodology was descriptive studies (50%). An additional 9% of studies were experimental in nature. Most of the peer-reviewed empirical literature came from U.S. Department of Veterans Affairs settings. A slight majority, 58% of peer-reviewed articles, identified a social worker as an author. The most frequently used key words in social work journals reflected mental health (33%), most focused on post-traumatic stress disorder (41%). Conclusions: Characterizing the social work literature continues to be a challenge. Social workers practice in a variety of arenas with veterans and should be afforded opportunities to engage in research especially endeavors that focus on marginalized populations of veterans.
User involvement in social work innovation: A systematic and narrative review
Authors: Müller Maja , Pihl-Thingvad Signe 
Published: April 2019

Summary This article focuses on user involvement in social work innovations in the public sector and provides an overview of how public innovation via user involvement in social work has been studied to date. Through analyses based on a systematic review combined with a narrative review of the identified literature, we offer a typology of social work innovations. The article concludes by discussing possibilities and barriers inherent in user involvement in social work and suggesting topics for future research. Findings Through a systematic review we identify the relevant literature describing different kinds of user involvement in social work innovation. In the narrative review, we analyze the literature and identify three types of innovation: user-centered innovation, co-produced innovation, and citizen-driven innovation. With empirical examples we illustrate the different types of innovation and the citizen’s role in the different innovation processes. Application The typology provides an analytic tool to differentiate types of innovation and user involvement, but it may also function as inspiration to practitioners to reflect more about the roles of users and frontline workers and to be more aware of existing barriers when designing new social initiatives in the public sector.
Surgical Treatment of Severe Hallux Abductovalgus With Dislocation of the First Metatarsophalangeal Joint: A Case Presentation and Surgical Technique
Authors: Tootle Kevin , Hollnagel JennaLou , Kinmon Kyle 
Published: April 2019

Severe hallux abductovalgus deformity with dislocation and contracture at the first metatarsophalangeal joint is difficult to manage, especially in the presence of concomitant, long-standing rheumatoid arthritis. This article highlights a novel surgical technique that may be used to successfully address this challenging condition while minimizing the likelihood of complications. Levels of Evidence: Level IV
Effectiveness and safety of physician–pharmacist collaborative care for rheumatoid arthritis patients: The Changi General Hospital’s experience
Authors: Lee Elena Meishan , Vasudevan Archana Ramaswamy , Wee Ian Yew Jin , Yeow Serene Dingju , Dinh Vinh Thuc Uyen 
Published: April 2019

Background: Increasing demand for follow-up of rheumatoid arthritis has encouraged pharmacists to collaborate with physicians to assist with patient care. Objective: The aim of this study was to assess the effectiveness and safety of the collaborative care model in a rheumatoid arthritis clinic. Methods: We performed a retrospective review of patient case notes and medication records from March 2013 to February 2016. The effectiveness and safety of collaborative care was examined in pre-implementation (standard care) versus post-implementation (collaborative care) cohorts. All patients were assessed for 12 months. Effectiveness of clinic was measured using the percentage of patients that achieved optimal doses of non-biologic disease-modifying anti-rheumatic drugs (nb-DMARDs). Clinic safety performance was evaluated based on the percentage of patients in each cohort that achieved compliance to in-house hospital guidelines on nb-DMARD monitoring. Other clinic safety factors monitored included the incidence and characteristics of nb-DMARD-associated adverse drug events. Results: Thirty-eight patients who had received standard care and collaborative care were reviewed. More patients receiving collaborative care achieved nb-DMARD dose optimization within a year of initiation of therapy (68.4% vs 39.5%; p-value < 0.05). Compliance to safety recommendations from hospital guidelines on nb-DMARD monitoring was significantly higher in the collaborative care group (70.6% vs 44.1%; p-value < 0.05). Collaborative care resulted in a higher incidence of nb-DMARD-associated adverse drug events being detected (26.3% vs 18.4%; p-value < 0.05). The most common adverse drug events were gastrointestinal (29.4%), dermatological (17.6%), and hematologic (17.6%), the majority being mild in severity. Conclusion: Collaborative rheumatoid arthritis care contributed to improvements in nb-DMARD dose optimization, compliance to hospital guidelines on monitoring, and the detection of nb-DMARD-related adverse drug events.
On Fights and Break-ups Between Couples
Authors: Mukherjee Conan 
Published: April 2019

We present a new economic model of romantic relationships by theorizing breakup as an intertemporal process, unlike the traditional static approach in terms of outside options. Contrary to Becker (2009), our approach underlines the possibility of divorces even when outside options are less than gains from marriage. This allows us to provide a rationale for the anti-Benthamite legally mandated separation periods during divorce proceedings, within the Benthamite paradigm. Further, we provide a rational explanation for the curious tendency of partners of being in long periods of acrimonious fight before making up by undertaking actions that they could have undertaken right at the start of their fight. Finally, in line with a UK government report (1989), our paper posits that unions without legal recognition are likely to be more unstable in comparison to legally recognized marriages. JEL codes: K36, C72,D90
Volatile organic compound profiles in outlet air from extracorporeal life-support devices differ from breath profiles in critically ill patients
Authors: Leopold Jan Hendrik , Philipp Alois , Bein Thomas , Redel Andreas , Gruber Michael , Schultz Marcus J. , Abu-Hanna Ameen , Brinkman Paul , Janssen Hans-Gerd , Bos Lieuwe D.J. 
Published: April 2019

IntroductionIt is highly uncertain whether volatile organic compounds (VOCs) in exhaled breath of critically ill intensive care unit patients are formed in the lung locally, in the air compartment or lung tissue, or elsewhere in the body and transported to the lungviathe bloodstream. We compared VOC mixtures in exhaled breath and in air coming from extracorporeal support devices in critically ill patients to address this issue.MethodsFirst, we investigated whether it was safe to connect an electronic nose (eNose) or a gas sampling pump to extracorporeal support membranes. Then, breath and air from extracorporeal support devices were collected simultaneously for continuous monitoring of VOC mixtures using an eNose. In addition, samples for gas chromatography/mass spectrometry (GC-MS) analysis were taken daily at the two measurement sites.Results10 critically ill patients were monitored for a median (interquartile range) duration of 73 (72–113) h; in total, we had 887 h of air sampling. The eNose signals of breath correlated moderately with signals of air from the extracorporeal support devices (R2=0.25–0.44). After GC-MS analysis, 96 VOCs were found both in breath and air from the extracorporeal support devices; of these, 29 (30%) showed a significant correlation (p<0.05) between the two measurement sites, of which 17 were identified. VOCs that did not correlate were found in a higher concentration in breath than in air from the extracorporeal support devices.ConclusionThis study suggests VOC analysis in the extracorporeal circulation is safe, and that VOCs of nonpulmonary origin can be measured in the breath and in the extracorporeal circulation of critically ill patients. For VOCs that did not correlate between the two measurement sites, the breath concentration was higher, suggesting pulmonary production of these molecules in a highly selected population of patients that received extracorporeal support.
The characterisation of interstitial lung disease multidisciplinary team meetings: a global study
Authors: Richeldi Luca , Launders Naomi , Martinez Fernando , Walsh Simon L.F. , Myers Jeffrey , Wang Bonnie , Jones Mark , Chisholm Alison , Flaherty Kevin R. 
Published: April 2019

Multidisciplinary team (MDT) diagnosis of interstitial lung disease (ILD) has been proposed as a gold standard, but there are no formal recommendations for MDT process or composition and limited knowledge regarding prevalence in routine practice.We performed a systematic evaluation of ILD diagnostic practice across a range of healthcare settings around the world. Electronic questionnaires were distributed across all global regionsviasociety and collaborators networks.Responses from 457 unique centres across 64 countries were included in the analysis. Of the 350 (76.6%) centres holding formal meetings, the majority held face-to-face MDT meetings (80%), for a minimum of 30 min (93%), and discussed diagnosis (96.9%) and patient management (94.9%) at the meetings. Compared with non-academic and academic non-ILD centres, ILD academic centres reported a higher ILD caseload, held more formal MDT meetings, and were more likely to include histopathology and rheumatology specialists in their diagnostic team. Of the centres holding MDT meetings, 5.5% routinely discussed all new cases at such meetings.An MDT approach to ILD diagnosis is consistently interpreted and widely implemented across a range of routine care settings around the world. This observation will inform future ILD diagnostic agreement studies and diagnostic pathway recommendations.
On Understanding Mattessich and Ijiri: A Study of Accounting Thought by Nohora García
Authors: Fukui Yoshitaka , Saito Shizuki 
Published: March 2019

Abstract
Nohora García’s meticulously researched work on Richard Mattessich and Yuji Ijiri cannot be timelier when the marginal productivity of mainstream empirical accounting studies seems to become smaller and smaller. It is high time to revisit neglected but important contributions of axiomatic approach in the 1960s and 1970s in order to enrich our understanding of accounting phenomena.
Proposals to recognize Petalonia tenella comb. nov. and to resurrect Hapterophycus canaliculatus (Scytosiphonaceae, Phaeophyceae)
Authors: Santiañez Wilfred John E. , Kogame Kazuhiro 
Published: March 2019

Abstract
The brown algal family Scytosiphonaceae has recently received considerable attention resulting in the description of several new genera and species. However, members of the genus Scytosiphon and Petalonia remain polyphyletic. By integrating multi-gene phylogenetic data (mitochondrial cox3 and plastid psaA and rbcL genes) with their known morpho-anatomies and life histories, we herein resurrect Hapterophycus canaliculatus, currently considered a member of genus Scytosiphon, and transfer Scytosiphon tenellus to the genus Petalonia.
Enhancement of Heat Transfer Performance Using Ultrasonic Evaporation
Authors: Song Jitian , Feng Yongxia , Tian Wei , Liu Jianbo , Wang Yening , Xu Xiaofei 
Published: March 2019

Abstract
The ultrasonic evaporator is a new type of evaporation equipment which uses ultrasonic technology to assist evaporation of liquid materials. Due to the lack of mechanism of ultrasonic technology to enhance the heat transfer in evaporation process, there are few reports on the use of ultrasonic evaporator in industrial production. The tap water was selected as experimental material and the heat transfer performance of ultrasonic evaporator was studied. It could be obtained from the single factor analysis that the heat transfer coefficient increased first and then decreased with the increase of ultrasonic power density. The increase of heat transfer due to the increase of temperature difference is basically stable at 20 %. When the ultrasonic wave acts on evaporator, the heat transfer coefficient would increase about 17.06 %–29.85 %. According to the orthogonal test and analysis of variance, it can be obtained that the influence of temperature difference on heat transfer coefficient is the largest, the second is feed flow rate, and evaporation time has the least influence.
Crystal structure of aqua-2,2′,2′′-(((nitrilo-κN-tris(ethane-2,1-diyl))tris(azanylylidene-κ3
N′,N′′,N′′′))tris(methanylylidene))tris(4-chlorophenolato-κ3
O,O′,O′′)neodymium(III), C27H26Cl3N4NdO4
Authors: Lee See Mun , Lo Kong Mun , Tiekink Edward R.T. 
Published: March 2019

Abstract
C27H26Cl3N4NdO4, monoclinic, P21/c (no. 14), a = 13.6408(1) Å, b = 20.3377(2) Å, c = 10.7272(1) Å, β = 109.896(1)°, V = 2798.34(5) Å3, Z = 4, R
gt(F) = 0.0258, wR
ref(F
2) = 0.0590, T = 100(2) K.
Harmonic waves solution in dual-phase-lag magneto-thermoelasticity
Authors: Rafiq Muhammad , Singh Baljeet , Arifa Samreen , Nazeer Muhammad , Usman Muhammad , Arif Shoaib , Bibi Mairaj , Jahangir Adnan 
Published: March 2019

Abstract
The current work analyzes the transmission behavior of plane harmonic waves in an isotropic medium. The observation is made for homogeneous type solid in the context of generalized dual phase lag model of thermoelasticity. Concept micro-temperature, where the microelements have different temperatures has also been considered. The basic focus of thework is to predict the influence of initially applied magnetic field on plane waves through the elastic solid. We have made an attempt to find exact solution of the problem using an analytical technique of a normal mode analysis method. The theoretical results are obtained for a generalized solid in order to test the numerical calculation of a magnesium crystal. It is found that the magnetic field reduces the strength of the attenuation factor.
Multiplicative topological indices of honeycomb derived networks
Authors: Tang Jiang-Hua , Habib Mustafa , Younas Muhammad , Yousaf Muhammad , Nazeer Waqas 
Published: March 2019

Abstract
Topological indices are the numerical values associated with chemical structures that correlate physico-chemical properties with structural properties. There are various classes of topological indices such as degree based topological indices, distance based topological indices and counting related topological indices. Among these classes, degree based topological indices are of great importance and play a vital role in chemical graph theory, particularly in chemistry. In this report, we have computed the multiplicative degree based topological indices of honeycomb derived networks of dimensions I, 2, 3 and 4.
A Centrifugal Compressor Performance Map Empirical Prediction Method for Automotive Turbochargers
Authors: Fatsis Antonios , Vlachakis Nikolaos , Leontis George 
Published: March 2019

Abstract
Centrifugal compressor performance map prediction is of primary importance for safe and effective operation of turbochargers. This article is a contribution on compressor map prediction using empirical relations based on automotive turbocharger manufacturers’ performance maps. The present method evaluates the minimum and the maximum air flow rates, as well as the maximum compressor pressure ratio by original empirical equations exploiting impeller geometrical data. Newly introduced equations based on the mass flows and the maximum pressure ratio acquired above provide the compressor characteristic lines. The method is validated by applying it to various commercial automotive turbochargers with known performance maps from their manufacturers. At intermediate values of impeller speed, where the turbocharger is expected to match the engine, the computed compressor map agrees to the manufacturer’s data, while, differences are observed at the maximum impeller speed line. From the cases examined, it can be stated that the present model can be applied to predict small diameter, high rotational speed compressor performance, particularly at the high efficiency region that the turbocharger is supposed to match the IC engine.
Different substituent effects on the supramolecular arrays in some (E)-halo- and nitro-benzaldehyde oximes: confirmation of attractive π(C=N)···π(phenyl) interactions
Authors: Gomes Ligia R. , Low John N. , van Mourik Tanja , Früchtl Herbert , de Souza Marcus V.N. , da Costa Cristiane F. , Wardell James L. 
Published: March 2019

Abstract
The crystal structures and Hirshfeld surface analyses are reported for four aldoximes, (E)-X–C6H4CH=N–OH [X = 3-Cl (1), 4-F (2), 2-O2N (3) and 4-O2N (4)]. The strong classical O–H · · · N hydrogen bonds involving the oxime group generate C(3) chains in compound 1, in contrast to the R2
2(6) dimers formed in compounds 2–4; such arrangements have been shown to be the most frequently found for oximes other than salicylaldoximes (2-hydroxybenzaldehyde oximes). In general, weaker intermolecular interactions involving the X substituents, as well as C–H · · · O and π · · · π interactions have significant effects on the supramolecular arrays generated in the aggegation. A further important interaction in compound 1, and to a lesser extent in compound 4, is a π(C=N) · · · π(phenyl) molecular stacking. A data base search has indicated that short Cg(C=N) · · · Cg(phenyl) distances, <3.3 Å (Cg = centre of gravity), have been found in various compounds, including other oximes. A theoretical study was carried out starting from the crystal structure data of compound 1, with optimisation at the BLYP-D3/def2-DZVP level, as well as at the higher PBE0/ma-def2-TZVP level. Breakdown of the interaction energy into separate contributions was achieved using SAPT (using the jun-cc-pvdz basis set). Overall, the calculations indicate that the π(C=N) ·· · π(phenyl) interaction is attractive, with a magnitude of 14–18 kJ mol−1.
The Effect of Consanguinity on Between-Individual Identity-by-Descent Sharing
Authors: Severson Alissa L , Carmi Shai , Rosenberg Noah A 
Published: March 2019

Abstract
Consanguineous unions increase the rate at which identical genomic segments are paired within individuals to produce runs of homozygosity (ROH). The extent to which such unions affect identity-by-descent (IBD) genomic sharing between rather than within individuals in a population, however, is not immediately evident from within-individual ROH levels. Using the fact that the time to the most recent common ancestor (TMRCA) for a pair of genomes at a specific locus is inversely related to the extent of IBD sharing between the genomes in the neighborhood of the locus, we study IBD sharing for a pair of genomes sampled either within the same individual or in different individuals. We develop a coalescent model for a set of mating pairs in a diploid population, treating the fraction of consanguineous unions as a parameter. Considering mating models that include unions between sibs, first cousins, and nth cousins, we determine the effect of the consanguinity rate on the mean TMRCA for pairs of lineages sampled either within the same individual or in different individuals. The results indicate that consanguinity not only increases ROH sharing between the two genomes within an individual, it also increases IBD sharing between individuals in the population, the magnitude of the effect increasing with the kinship coefficient of the type of consanguineous union. Considering computations of ROH and between-individual IBD in Jewish populations whose consanguinity rates have been estimated from demographic data, we find that, in accord with the theoretical results, increases in consanguinity and ROH levels inflate levels of IBD sharing between individuals in a population. The results contribute more generally to the interpretation of runs of homozygosity, IBD sharing between individuals, and the relationship between ROH and IBD.