bluuebunny/crossref_metadata_2025_split huggingface dataset:
SECRETORY STRUCTURES AND ESSENTIAL OIL COMPOSITION OF SELECTED INDUSTRIAL SPECIES OF LAMIACEAE
Authors: Kowalski Radosław , Kowalska Grażyna , Jankowska Monika , Nawrocka Agnieszka , Kałwa Klaudia , Pankiewicz Urszula , Włodarczyk-Stasiak Marzena 
Published: April 2019

The objective of the study was to perform micromorphological analyses of the secretory structures of leaves and stems of oil-bearing industrial plants from the Lamiaceae family such as lemon balm (Melissa officinalis L.), peppermint (Mentha × piperita L.), sage (Salvia officinalis L.), marjoram (Origanum majorana L., syn. Origanum dubium Boiss.), rosemary (Rosmarinus officinalis L.) and common thyme (Thymus vulgaris L.) using light microscope and scanning electron microscope. In addition, an estimation of the content of volatile substances in the plant species under study was performed using GC-MS, as well as the qualitative and quantitative analysis of essential oil, that is an important component in terms of the estimation of raw material applicability for use in the industry. In the epidermal cells of studied plants, 2 types of Lamiaceae-type glandular trichomes were identified: short- and long-stalked capitate glandular trichomes with single- and bicellular secretory capitulum, and peltate glandular trichomes with eight- and over a dozen-cell secretory capitulum. Capitate trichomes were densely distributed on the surface of the epidermis, while peltate trichomes were sparse, though regular, and were situated in depressions. Glandular trichomes were found more frequently on leaves than on stems. The cuticle of the abaxial of leaf was characterized in most cases by the occurrence of larger average diameter peltate trichomes compared to the cuticle of the adaxial side of leaf. Peppermint produced the largest structures accumulating essential oil on the leaves (average diameter of peltate trichomes – 78.48 µm on the adaxial side of leaf, up to 96.43 µm), while on the stem, the highest average diameter of the peltate trichomes was observed in sage (an average of 75.53 µm, up to 85.99 µm). The lemon balm was characterized by the presence of capitate and peltate trichomes with the smallest diameter (an average of 44.26 µm). Lemon balm was characterized by the greatest density of glandular trichomes compared to other plant species. Among the plants studied, the highest content of oil was noted in the case of thyme and peppermint (2.22% and 2.20% v/w, respectively), and the lowest in green parts of lemon balm (0.17% v/w). The isolated essential oils contained predominantly components from the groups of monoterpenes and sesquiterpenes, and it is the presence of those substances that determines the possibility of utilizing the plants studied for a variety of purposes.
INFLUENCES OF PRE-SOWING TREATMENTS ON THE GERMINATION AND EMERGENCE OF DIFFERENT MULBERRY SPECIES SEEDS
Authors: Gündüz Kazim , Karaat Fırat Ege , Uzunoğlu Fulya , Mavi Kazım 
Published: April 2019

Morus genus includes more than 20 species, some of which are commercially important mulberries with different fruit color and shape. Even though the trees of those species are propagated by rooting of cuttings in practice, mulberry seeds are of importance for breeding studies and rootstock seedling propagation. For that reason, this study was conducted to improve the seed performance of four mulberry species by different pre-sowing treatments including; 3% KNO3, GA3 at 500 ppm, organic priming with herbal tea brewed from marigold flowers petals and hydro priming. Results of the parameters of emergence characteristics and seedling vigor were evaluated. According to the results that varied between different species and pre-treatments, since emergence percentage and time, and seedling vigor were improved by the treatments, it was concluded that pre-sowing applications, especially GA3 and hydro priming, were beneficial in improving the seed performance of mulberry species included in the study.
Effects of orally administered raltegravir in cats with experimentally induced ocular and respiratory feline herpesvirus-1 infection
Authors: Spertus Chloe B. , Pennington Matthew R. , Van de Walle Gerlinde R. , Badanes Zachary I. , Judd Bonnie E. , Mohammed Hussni O. , Ledbetter Eric C. 
Published: April 2019

Abstract

OBJECTIVE
To determine the effects of orally administered raltegravir in cats with experimentally induced ocular and respiratory feline herpesvirus-1 (FHV-1) infection.

ANIMALS
14 healthy 6-month-old unvaccinated specific pathogen–free cats.

PROCEDURES
On day 0, all cats were experimentally inoculated by topical application of 0.1 mL of a solution containing 106 plaque-forming units of FHV-1 strain FH2CS to the inferior conjunctival fornix of each eye. Cats were randomly assigned to receive either raltegravir (80 mg; n = 7) or lactose (250 mg; vehicle; 7), PO, every 12 hours for 14 days beginning on day 1. Cats were assigned clinical ocular and respiratory disease scores every other day from days 0 to 30. Conjunctival swab specimens were collected for detection of FHV-1 by virus isolation and real-time PCR assay at 3-day intervals from days 0 to 30. Confocal microscopy was performed on days 0 and 10 to assess corneal epithelial leukocyte infiltration. The assessed variables and duration of FHV-1 shedding were compared between the 2 treatment groups.

RESULTS
Cats in both groups developed moderate to severe conjunctivitis and ulcerative keratitis characteristic of FHV-1 infection. Median duration of FHV-1 shedding was shorter and signs of ocular and respiratory disease were less severe for raltegravir-treated cats than for vehicle-treated cats. However, the mean conjunctival FHV-1 titer and corneal epithelial leukocyte count did not differ between the 2 groups.

CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested orally administered raltegravir might be effective for alleviation of ocular and respiratory signs of FHV-1 infection in cats. (Am J Vet Res 2019;80:490–497)
Pharmacokinetics and competitive pharmacodynamics of ADP-induced platelet activation after oral administration of clopidogrel to horses
Authors: Norris Jeffrey W. , Watson Johanna L. , Tablin Fern , Kozikowski Tania A. , Knych Heather K. 
Published: April 2019

Abstract

OBJECTIVE
To determine pharmacokinetics and pharmacodynamics after oral administration of a single dose of clopidogrel to horses.

ANIMALS
6 healthy adult horses.

PROCEDURES
Blood samples were collected before and at various times up to 24 hours after oral administration of clopidogrel (2 mg/kg). Reactivity of platelets from each blood sample was determined by optical aggregometry and phosphorylation of vasodilator-stimulated phosphoprotein (VASP). Concentrations of clopidogrel and the clopidogrel active metabolite derivative (CAMD) were measured in each blood sample by use of liquid chromatography–tandem mass spectrometry, and pharmacokinetic parameters were determined with a noncompartmental model.

RESULTS
Compared with results for preadministration samples, platelet aggregation in response to 12.5μM ADP decreased significantly within 4 hours after clopidogrel administration for 5 of 6 horses. After 24 hours, platelet aggregation was identical to that measured before administration. Platelet aggregation in response to 25μM ADP was identical between samples obtained before and after administration. Phosphorylation of VASP in response to ADP (20μM) and prostaglandin E1 (3.3μM) was also unchanged by administration of clopidogrel. Time to maximum concentration of clopidogrel and CAMD was 0.54 and 0.71 hours, respectively, and calculated terminal-phase half-life of clopidogrel and CAMD was 1.81 and 0.97 hours, respectively.

CONCLUSIONS AND CLINICAL RELEVANCE
Clopidogrel or CAMD caused competitive inhibition of ADP-induced platelet aggregation during the first 24 hours after clopidogrel administration. Because CAMD was rapidly eliminated from horses, clopidogrel administration may be needed more frequently than in other species in which clopidogrel causes irreversible platelet inhibition. (Am J Vet Res 2019;80:505–512)
Effect of metformin gel against imiquimod–induced psoriasis in mice
Authors: Haider F. Alsaedi  , Haider Falih Shamikh Al-Saedi  , Adeeb Ahmed Kadhim  Al-Zubaidy  , Mukhallad Abdul Kareem Ramadhan  , Hussein Abdelamir Mohammad  
Published: April 2019

Imiquimod-induced psoriasis is an animal model of psoriasis. The antidiabetic metformin had anti-inflammatory, immunomodulation, antiangiogenesis and antiproliferative effect. The objective of this study was to evaluate the possible beneficial effect of metformin gel against imiquimod-induced psoriasis-like form by scoring the erythema and scaling besides measuring of tissue homogenate levels of IL17/IL23. Swiss albino mice were used in this experiment imiquimod 5% cream applied on shaved back of mice for six days, and this is an induction group and compared with a negative control group that involved mice treated with ointment base only for six days. Third group; metformin 10% gel applied on the back of mice with imiquimod for six days. The fourth group included used of metformin 15% gel with imiquimod for six days. This data was analysed for significant level when p ≥ 0.05 by using either ANOVA test for biochemical parameters levels evaluation. Furthermore, imiquimod 5% cream of induction group caused an elevation of inflammatory parameters; IL17 and IL23 in skin tissue homogenate when being compared to IL17 and IL23 level of the control group. Whereas, metformin 10% gels showed levels of IL17 and IL23 with significant different from induction group. In addition, metformin 15% gels exerted a significantly low level of IL17 and IL23. The possible considerable antipsoriatic activity of topical metformin gel through reducing scaling and erythema and mediated through modest anti-inflammatory effects by suppressing levels of IL17/23.
Detection of BCR-ABL gene in Chronic Myeloid Leukemia patients treated with Tyrosine Kinase Inhibitors Drugs by Gene Expert System
Authors: Maysaa Ali Abdul Khaleq  , Hussein Ali Saheb  , Ahmed M Sultan  , Mohsen A. N. Alrodhan  
Published: April 2019

Chronic myeloid leukaemia (CML) is one of the human fatalities caused by genetic mutation and chromosomal translocation, a BCR-ABL fusion gene and as a result, Philadelphia chromosome is formed. The irregular tyrosine kinase activity of the encoded protein by this gene causes the establishment of the disease. This study was conducted at the period from September 2016 to February 2017,100 Iraqi CML patients were divided into two groups, first group of 50 patients were received Imatinib 400-800 mg/day, second group of another 50 patients were received 800 mg/day Nilotinib, WBC were microscopically counted using improved Neubauer ruled hemocytometer counting chamber. The results of WBC count in different disease duration and stages of treatment in the group of patients treated with Imatinib showed that highest WBC count was observed in newly diagnosed patients while there was a significant reduction in the WBC count after one month, after one year and final dose of treatment were 11.8, 6.4 and 8.1 respectively, on the other hand the results of WBC count in the group of patients treated with Nilotinib showed that the highest WBC count was observed in newly diagnosed patients 87.54± 8.71 whereas the WBC count after one month, one year and at the final dose of treatment were 7.3, 6.8, 7.9 respectively with significant reduction in the WBC count. The results of the CML patient’s distribution according to BCR-ABL gene analysis in the patient's group treated with Imatinib showed that high concentration in newly diagnosed patients 4.753 as compared with significant reduction with other stages of treatment after one month and after one year 0.94 and 0.09 respectively.
An experimental study to assess the effectiveness of fresh amla juice with elemental iron versus elemental iron supplementation on anemia among adolescent girls in selected school at Chennai
Authors: Devi JK  , Jainvanitha  , Fabiola Dharaj  , Vasantha S  
Published: April 2019

The present study was undertaken to assess the effectiveness of fresh amla juice with elemental iron versus elemental iron supplementation on anaemia among adolescent girls in selected school at Chennai. A total of 50 adolescent girls within the age group of 13-16years.with mild to moderate anaemia from selected schools in Chennai were part of the study after obtaining the written informed consent and assent as per guidelines. After recruiting, the participants were randomly grouped into two groups. Group 1: (n=25) 20ml fresh amla juice was given before lunch daily for 30 days and elemental iron 100 mg per week. Group 2: (n=25) 100mg of elemental iron per week for 30 days. Result – after intervention in the experimental group I the mean haemoglobin level increased (1.03gm/dl) than in control group II. The present study provides further evidence for the beneficial effects of amla juice in the management of anaemia. It concluded that fresh amla juice helps in iron absorption thereby increasing the HB level in experimental group I. We recommend further detailed studies in this area to recommend amla juice as a nutritive supplement for the management of anaemia.
Por uma educação científica que problematize a mídia
Authors: Cardoso Danilo , Gurgel Ivã 
Published: April 2019

O objetivo do trabalho é defender que umas das finalidades mais importantes para o ensino de ciências é a de problematizar a mídia. Para isso, primeiramente é feita uma discussão teórica sobre a epistemologia e a educação freireana. Nela, dá-se destaque ao papel da problematização no processo de conscientização. Em seguida, é realizada uma discussão sobre o papel da mídia na sociedade, ressaltando-se seus usos políticos. A partir desta discussão faz-se uma revisão de artigos sobre Educação e Mídia e Mídias e Ensino de Ciências com o objetivo de destacar as principais potencialidades desta aproximação. Por fim, argumenta-se que somente uma educação científica que problematize a mídia permite uma formação cidadã e crítica.
A CRISE NA EDUCAÇÃO DE HANNAH ARENDT E A CRÍTICA ÀS CONCEPÇÕES EDUCACIONAIS DO PRAGMATISMO
Authors: Andrade Flávio Rovani de 
Published: April 2019

Este artigo procura expor a crítica da filósofa Hannah Arendt (1906-1975) às concepções educacionais do Pragmatismo, em especial ao pragmatismo de John Dewey (1859-1952). Primeiramente, é exposta brevemente a teoria educacional de Hannah Arendt com base no texto A crise na educação, seu único texto eminentemente educacional. Por se articular com o todo de sua obra, faz-se também incursões na vasta obra da autora, a fim de ampliar a compreensão do sentido da educação no conjunto da filosofia e da teoria política arendtiana. Posteriormente, é tratada a crítica objeto deste artigo, propriamente dita, com base numa análise do texto Democracia e Educação, de Dewey, à luz da teoria arendtiana
Filosofía, educación e infancia
Authors: Duhart Olga Grau 
Published: April 2019

El texto propone una perspectiva de articulación de la filosofía, la educación y la infancia en una suerte de trama de potencias que pueden concurrir fructíferamente en una propuesta que legitime y visibilice a niñas y niños como sujetos pensantes y productores de cultura. Se hace referencia al programa de Filosofía para Niños del filósofo Matthew Lipman y al valor de su proyecto educativo, como también al aporte de otros filósofos, especialmente el de Walter Kohan, que nos permiten pensar la relación entre filosofía, educación e infancia con mayor complejidad. Finalmente, se reflexiona sobre la significación de las preposiciones en las expresiones de filosofía con o para niños y niñas.
Simón Rodríguez, la bildung de un extraño
Authors: Valera-Villegas Gregorio 
Published: April 2019

Este trabajo es un ejercicio de aproximación a la bildung de un personaje, Simón Rodríguez. La bildung de un extaño según nuestra mirada. Un ejercicio otro, distinto, al menos, sobre un venezolano, latinoamericano por antonomasia, un pensador cosmopolita; del cual se ha dicho que fue el filósofo (el Sócrates de Caracas y/o de América), un político, un educador. En él realizamos una suerte de hermenéutica del texto escrito, narrado, y de la acción contada por testigos oculares. La carta, la biografía, el ensayo filosófico y pedagógico no sirvieron de pretextos para presentar a un Rodríguez, además del estraño, escritor. Finalmente, puede decirse, que se intenta contribuir, en alguna medida, con el estudio de la vida, del pensamiento y de la obra del así llamado, Don Simón Rodríguez.
Filosofia no Ensino Médio.
Authors: Tomazetti Elisete Medianeira , Marçal Katiuska I. , Ribeiro Tatiana De Melo 
Published: April 2019

Neste espaço relataremos o desenvolvimento do projeto de pesquisa Filosofia, Cultura Juvenil e Ensino Médio desenvolvido no período de junho de 2004 a junho de 2009, na Universidade Federal de Santa Maria (UFSM), no Rio Grande do Sul. A coordenação foi realizada pela professora Elisete Medianeira Tomazetti, vinculada ao Departamento de Metodologia e Ensino (MEN), do Centro Educação e responsável pelas disciplinas de Didática da Filosofia, Pesquisa para o Ensino de Filosofia e Estágio Curricular Supervisionado, do Curso de Filosofia da UFSM. Desde seu início o projeto contou com vários alunos do Curso de Filosofia da UFSM. Alguns se agregavam ao grupo durante certo período e assim que concluíam seu curso e precisavam buscar emprego, em outras localidades, acabavam deixando o grupo. Outros, devido a bolsas de iniciação científica, oriundas de diferentes editais, permaneceram durante todo o período de desenvolvimento da pesquisa, nas diferentes etapas. O desenvolvimento da pesquisa procurou sempre fomentar o interesse dos alunos em dar continuidade a seus estudos de pós-graduação strictu sensu, seguindo com pesquisas na mesma temática. Muitos trabalhos, a partir desta pesquisa, foram elaborados e apresentados pelos participantes do grupo de pesquisa em eventos da área, ajudando a fortalecer esse campo teórico, ainda com certa carência de estudos e pesquisa significativos no contexto brasileiro. Da mesma forma, a pesquisa ajudou tornar mais visível a problemática do ensino de filosofia na Escola Básica no contexto do Curso de Filosofia e do Programa de Pós-Graduação em Educação da UFSM, principalmente.
Ela pinta como se estivesse bordando: pinturas e vestimentas na obra de Maria Auxiliadora
Authors: Negreiros Hanayrá 
Published: April 2019

“O pessoal é político”. É através dessa breve, porém assertiva frase, que começamos a ler o texto curatorial que nos introduz à vida, às cores e às texturas de Maria Auxiliadora – mulher negra, mineira, artista plástica e detentora de muitas histórias e memórias.
Análisis espectral de las lesiones melanocíticas adquiridas
Authors: Álvarez Iriana , Vivas Sandra , Muñoz Aarón 
Published: April 2019

Introducción. A lo largo de la historia se han establecido distintos métodos para obtener información morfológica de las lesiones pigmentadas. La regla de oro para el diagnóstico es la biopsia; sin embargo, se han desarrollado técnicas ópticas no invasivas como la espectrofotometría de reflexión difusa. Objetivo. Caracterizar las lesiones melanocíticas adquiridas con espectrofotometría de reflexión difusa. Materiales y métodos. Se hizo un estudio de tipo validación prospectiva, con diseño de cohorte. La población estuvo constituida por 63 pacientes con lesiones pigmentadas adquiridas que acudieron a la consulta del Servicio de Dermatología, Ciudad Hospitalaria Dr. Enrique Tejera. La muestra incluyó 120 nevos clasificados por su diagnóstico clínico e histopatológico. Resultados. Se evidenciaron diferencias de reflectancia entre cada una de las lesiones estudiadas, y el nevo displásico fue el que presentó mayor absorción de melanina, lo cual se relaciona con que, de estas, es la lesión de mayor profundidad en la piel.Conclusión. Los nevos melanocíticos estudiados se caracterizan por presentar un espectro definido. Se recomienda incluir la espectrofotometría de reflexión difusa como método accesorio de diagnóstico y seguimiento en la consulta dermatológica.
Designing Dialogue Journal to Guide Teaching Practice Process through Online Tutorial at Universitas Terbuka
Authors: Andayani A. , Julaeha Siti 
Published: April 2019

During this time, PGSD Program at UT provides the face-to-face tutorial (TTM) for practice courses such as the Strengthening of Teaching Skill (PKM). By reason of the students are spread far apart and the number is less, so it is inefficient to organize TTM for PKM. Therefore, in the year of 2017, it was conducted a trial of an online tutorial for PKM. Whereas the tutor manages the online tutorial activity from a distance, the supervisor guides the teaching practice activities of the students directly in the classroom. The challenges occur due to student failure in interpreting tutor direction, and uncontrolled validity of teaching practice process. To answer the challenge, a Dialogue Journal is designed, as an instrument that presents the validity of the supervision process. Through a descriptive method approach, it will be developed the pattern of online tutorial activities for PKM conducted by UT. In addition, some concepts of online dialogue and teaching supervision activities will be reviewed as well. Based on reviews of a document and the results of observation of the ongoing online tutorial, the hypothetical design of the dialog journal will be proposed as well as to be presented the pattern of the online tutorial with journal dialogue for PKM.
Practices of Human Resource Management in Tribhuvan University
Authors: Shrestha Milan 
Published: April 2019

Human Resource Management (HRM) has been a crucial issue for Tribhuvan University (TU) due to the presence of a high number of students and teachers within the University Structure. The main purpose of this study was to explore the practices of the HRM in the TU. I adopted socio-constructivism as a research paradigm and narrative inquiry as the research design which is qualitative in nature. It used in-depth interview technique to collect information which was supported by literature review. TU conducts its overall human resource activities in coordination with executive bodies, campus chief, and line agencies like TUSC. The executive body is responsible for the entire HRM practices and other bodies have their own peculiar functions. For Instance, TUSC conducts the job design, job analysis, selection, recruitment, and performance appraisal process in the entire TU. HRM practices are familiar to the rules and regulations of TU and adopt them.
Pembelajaran Kitab Kuning pada Pondok Pesantren Hidayatullah Ternate
Authors: Bachrong Faizal 
Published: April 2019

Pengkajian kitab kuning di Pesantren merupakan unsur penting dari padanya, dan hal ini secara umum cenderung mengalami kemunduran, karena berbagai hal. Karena itu pengkajian tentang pemanfaatan kitab kuning di pesantren penting dilakukan. Penelitian ini menyoroti realitas pengkajian kitab kuning di pesantren. Fokus penelitian ini adalah PP HIdayatullah Ternate. Karena penelitian ini merupakan penelitian kualitatif, maka teknik pengumpulan datanya adalah wawancara, observasi dan studi dokumen dan pustaka. Analisis datanya adalah deskreprif kualitatif. PP Hidayatullah Ternate termasuk pondok pesantren kombinasi yang selain membina satuan pendidikan formal berupa sekolah dan madrasah, juga membina kepesantrenan, termasuk pengajian kitab. Santri yang dibina di dalamnya laki-laki dan perempuan. Dalam program kepesantrenan selain salat berjemaah, hafalan Al Alquran dan hadits, juga ada taklim diniyah (pengkajian kitab) dan ada halaqah diniyah. Pengkajian kitab memilih 5 kitab yang digariskan oleh Pengurus Pusat Hidayatullah berkaitan dengan Aqidah, Fiqih, Tafsir. Sirah dan Bahasa Arab. Para pengajarnya adalah kader-kader Hidayatullah sendiri dan lainnya. Pengkajian kitab ini dengan metode ceramah dan kitab pegangannya adalah terjemahannya. Santri hanya mendengar tanpa memiliki kitabnya. Kendala utama adalah kemampuan berbahasa Arab uantuk pengkajian kitab, terutama bagi santri yang dapat digolongkan tidak memilikinya.
Kata Kunci: Pondok Pesantren, Hidayatullah Ternate, Pengkajian kitab.