bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vitamin D deficiency is associated with ethnicity and knee pain in a multi‐ethnic South‐East Asian nation: Results from Malaysian Elders Longitudinal Research (MELoR)
Authors: Mat Sumaiyah , Jaafar Mohamad Hasif , Sockalingam Sargunan , Raja Jasmin , Kamaruzzaman Shahrul Bahyah , Chin Ai‐Vyrn , Abbas Azlina Amir , Chan Chee Ken , Hairi Noran Naqiah , Othman Sajaratulnisah , Cumming Robert , Tan Maw Pin 
Published: April 2018

AbstractAimTo determine the association between vitamin D and knee pain among participants of the Malaysian Elders Longitudinal Research (MELoR) study.MethodThis was a cross‐sectional study from the MELoR study consisting of a representative group of 1011 community‐dwelling older persons (57% female), mean age 86.5 (54–94) years; 313 were Malays, 367 Chinese and 330 Indians. Participants were asked if they had knee pain. Levels of serum 25‐hydroxy cholecalciferol (25‐[OH]D), an indicator of vitamin D status, were measured using routine laboratory techniques.ResultsIn unadjusted analysis, presence of knee pain was significantly associated with vitamin D deficiency (odds ratio [OR] 1.42; 95% confidence interval (CI) 1.08–1.85, P 0.011). Vitamin D levels were significantly associated with ethnicity differences where Malays (OR 7.08; 95% CI 4.94–10.15) and Indians (OR 6.10; 95% CI 4.28–9.71) have lower levels of vitamin D compared to Chinese. Subsequent multivariate analysis revealed that the association between vitamin D deficiency and knee pain was confounded by ethnic differences.ConclusionA previous study suggested that vitamin D deficiency was associated with knee pain. This relationship was reproduced in our study, but we further established that the association was explained by ethnic variations. As vitamin D status is dependent on skin tone, diet and sunlight exposure, which are all effected by ethnicity, future studies are now required to determine whether a true relationship exists between vitamin D and knee pain.
Fingerprints of partial oxidation of biogenic magnetite from cultivated and natural marine magnetotactic bacteria using synchrotron radiation
Authors: Rodelli D. , Jovane L. , Roberts A.P. , Cypriano J. , Abreu F. , Lins U. 
Published: April 2018

SummaryMagnetotactic bacteria are a multi‐phyletic group of bacteria that synthesize membrane‐bound magnetic minerals. Understanding the preservation of these minerals in various environments (e.g., with varying oxygen concentrations and iron supply) is important for understanding their role as carriers of primary magnetizations in sediments and sedimentary rocks. Here we present X‐ray near edge structure (XANES) spectra for Fe in magnetotactic bacteria samples from recent sediments to assess surface oxidation and crystal structure changes in bacterial magnetite during early burial. Our results are compared with a XANES spectrum of cultivated Magnetofaba australis samples, and with magnetic properties, and indicate that oxidation of magnetite to maghemite increases with depth in the sediment due to longer exposure to molecular oxygen. These results are relevant to understanding magnetic signatures carried by magnetofossils in oxic sediments and sedimentary rocks of different ages.
Intra‐ and Interindividual Variability in the Behavioral, Affective, and Perceptual Effects of Alcohol Consumption in a Social Context
Authors: Franzen Minita , Sadikaj Gentiana , Moskowitz Debbie. S. , Ostafin Brian D. , aan het Rot Marije 
Published: April 2018

BackgroundWe examined the influence of interindividual differences in alcohol use on the intraindividual associations of drinking occurrence with interpersonal behaviors, affect, and perceptions of others during naturally occurring social interactions.MethodsFor 14 consecutive days, 219 psychology freshmen (55% female; Mage = 20.7 years, SD = 2.18) recorded their behaviors, affect, and perceptions in social interactions soon after an interpersonal event occurred. Interpersonal behaviors and perceptions were assessed in terms of dominance–submissiveness and agreeableness–quarrelsomeness. Participants also reported the number of alcoholic drinks consumed within 3 hours of each interaction. We considered the intraindividual associations of (i) having a drinking episode and (ii) the number of drinks during an episode with behaviors, affect, and perceptions and examined interindividual differences in drinking frequency and intensity during social interactions as potential moderators of these associations.ResultsSocial drinking frequency and intensity moderated the associations between drinking episode and behaviors, affect, and perceptions in social interactions. During a drinking episode, more frequent social drinkers perceived others as more dominant than less frequent social drinkers. During a drinking episode in which more alcohol was consumed than usual, more frequent social drinkers also reported behaving more dominantly and experiencing less pleasant affect.ConclusionsAs more frequent social drinkers had different interpersonal responses to drinking than less frequent social drinkers, including when they had consumed larger amounts of alcohol than usual, our results suggest a differential susceptibility to the effects of alcohol during naturally occurring social interactions among drinkers with varying drinking frequency.
Nurse‐led multidisciplinary initiatives to improve outcomes and reduce hospital admissions for older adults: The Care coordination through Emergency Department, Residential Aged Care and Primary Health Collaboration project
Authors: Marsden Elizabeth , Craswell Alison , Taylor Andrea , Coates Kaye , Crilly Julia , Broadbent Marc , Glenwright Amanda , Johnston Colleen , Wallis Marianne 
Published: April 2018

ObjectivesThis article describes the Care coordination through Emergency Department, Residential Aged Care and Primary Health Collaboration (CEDRiC) project.MethodsCEDRiC is designed to improve the health outcomes for older people with an acute illness. It attempts this via enhanced primary care in residential aged care facilities, focused and streamlined care in the emergency department and enhanced intersectoral communication and referral.ResultsImplementing this approach has the potential to decrease inappropriate hospital admissions while improving care for older people in residential aged care and community settings.ConclusionThis article discusses an innovative way of caring for older adults in an ageing population utilising the existing evidence. A formal evaluation is currently underway.
Stabilisation of acute‐on‐chronic liver failure patients before liver transplantation predicts post‐transplant survival
Authors: Huebener P. , Sterneck M. R. , Bangert K. , Drolz A. , Lohse A. W. , Kluge S. , Fischer L. , Fuhrmann V. 
Published: April 2018

SummaryBackgroundAcute‐on‐chronic liver failure (ACLF) is a severe complication of liver cirrhosis associated with excess short‐term mortality rates. Orthotopic liver transplantation (OLT) is a potentially life‐saving therapeutic modality for acute‐on‐chronic liver failure patients, but selection of transplant candidates with an acceptable post‐transplant outcome is difficult.AimTo assess the risk of liver transplantation in patients with ACLF, and to determine parameters that predict post‐transplant survival in this patient cohort.MethodsWe retrospectively analysed all 250 patients with cirrhosis who underwent their first liver transplantation between 2009 and 2014 at our institution, and assessed post‐transplant outcomes.ResultsOf 250 cirrhotic liver transplant recipients, 98 patients fulfilled the diagnostic criteria for acute‐on‐chronic liver failure in the 3‐month pre‐transplant period. Compared to non‐ACLF patients, ACLF was associated with significantly higher short‐term morbidity and mortality after liver transplantation (90‐day patient survival 96.1% non‐ACLF vs 72.4% ACLF patients, P < 0.0001). Clinical improvement in the pre‐transplant period, as defined by recovery of at least one previously failed organ system, was observed in 37 of 98 acute‐on‐chronic liver failure patients, mostly within several days after diagnosis. Most notably, clinical improvement prior to liver transplantation was associated with excellent post‐transplant survival rates that approximated non‐ACLF transplant recipients. Following the 90‐day post‐transplant period, patient survival and long‐term graft functions were comparable between ACLF and non‐ACLF liver transplant recipients for up to 5 years.ConclusionsAcute‐on‐chronic liver failure predicts adverse outcome after orthotopic liver transplantation. Given the dismal prognosis without transplantation, however, our results indicate that ACLF patients can be transplanted with comparably good outcomes, in particular patients who improve under conservative therapeutic measures.
Outcomes of early versus delayed laparoscopic cholecystectomy for acute cholecystitis performed at a single institution
Authors: Kohga Atsushi , Suzuki Kenji , Okumura Takuya , Yamashita Kimihiro , Isogaki Jun , Kawabe Akihiro , Kimura Taizo 
Published: April 2018

AbstractIntroductionDebate continues regarding the clinical outcomes of early laparoscopic cholecystectomy (ELC) versus delayed laparoscopic cholecystectomy (DLC) for acute cholecystitis (AC). The aim of this retrospective study was to compare clinical outcomes of ELC and DLC.MethodsThis study consisted of 465 patients who had undergone laparoscopic cholecystectomy for AC between January 2000 and February 2017. Patients were divided between an ELC group (patients who underwent laparoscopic cholecystectomy within 6 days of symptom onset, n = 288) and a DLC group (patients who underwent laparoscopic cholecystectomy at least 7 days from symptom onset, n = 177), and clinical outcomes were compared.ResultsOperation time (105 vs 124 min), length of postoperative hospital stay (4 vs 4 days), conversion rate (1.3% vs 10.7%), bile leak (0.3% vs 3.3%), residual calculus (2.4% vs 6.7%), and readmission (1.0% vs 6.7%) were significantly better in the ELC group. A history of upper abdominal surgery, grade II or grade III AC, preoperative percutaneous transhepatic gallbladder drainage, and time between symptom onset and surgery of more than 7 days were independent risk factors for conversion.ConclusionsELC for AC yields more favorable clinical outcomes than DLC.
Bond offerings in China
Authors: Klein Paul‐Olivier , Weill Laurent 
Published: April 2018

AbstractThis study appraises the value created by a bond offering in China, where high levels of state ownership and insider ownership raise concerns about the use of the proceeds. To estimate the impact of a bond issue on the firm's value, we apply an event‐study methodology on a sample of 481 issues of 347 Chinese companies over the period 2009–2013. It turns out that state ownership has a positive impact on the value of a bond offering for shareholders, which is consistent with an implicit guarantee of the issue by the state. For privately owned companies, insider ownership exerts a nonlinear impact on the firm's value, supporting an aligning effect in the use of the proceeds. Overall, the study confirms the key role of ownership structure in Chinese firms.
A Review of Recent Research on Individual‐Level Score Reports
Authors: Gotch Chad M. , Roduta Roberts Mary 
Published: April 2018

AbstractAs the primary interface between test developers and multiple educational stakeholders, score reports are a critical component to the success (or failure) of any assessment program. The purpose of this review is to document recent research on individual‐level score reporting to advance the research and practice of score reporting. We conducted a search for research studies published or presented between 2005 and 2015, examining 60 scholarly works for (1) the research focus, (2) stated or implied theoretical frameworks of communication, and (3) the characteristics of data sets employed in the studies. Results show that research on score properties, especially subscores, and score report design/layout are well‐represented in the literature base. The predominant approach to score reporting has been through a cybernetics tradition of communication. Data sets were often small or localized to a single context. We present example research questions from novel communication frameworks, and encourage our colleagues to adopt new roles in their relationships to stakeholders to advance score reporting research and practice.
Innovation in local economic development strategy: The Wireless Research Center of North Carolina
Authors: Clayton Paige A. 
Published: April 2018

AbstractInnovation in local economic development strategy is necessary to support struggling regions and foster growth across municipalities with varying resources and needs. This paper presents a case of innovation in local economic development strategy to illustrate how institutional entrepreneurship can be used as a tool to help local governments innovatively approach economic development strategy. Through the creation of the Wireless Research Center of North Carolina, institutional entrepreneurs transformed the institutionalized role for local government in economic development, while simultaneously creating a new institutional form that would support local development goals.
Screening for oropharyngeal dysphagia in older adults: A systematic review of self‐reported questionnaires
Authors: Magalhães Junior Hipólito V. , Pernambuco Leandro de Araújo , Lima Kenio C. , Ferreira Maria Angela F. 
Published: April 2018

BackgroundOropharyngeal dysphagia is a swallowing disorder with signs and symptoms which may be present in older adults, but they are rarely noticed as a health concern by older people. The earliest possible identification of this clinical condition is needed by self‐reported population‐based screening questionnaire, which are valid and reliable for preventing risks to nutritional status, increased morbidity and mortality.ObjectiveThe aim of this systematic review was to identify self‐reported screening questionnaires for oropharyngeal dysphagia in older adults to evaluate their methodological quality for population‐based studies.MethodsAn extensive search of electronic databases (PubMed (MEDLINE), Ovid MEDLINE(R), Scopus, Cochrane Library, CINAHL, Web of Science (WOS), PsycINFO (APA), Lilacs and Scielo) was conducted in the period from April to May 2017 using previously established search strategies by the two evaluators. The methodological quality and the psychometric properties of the included studies were evaluated by the COSMIN (Consensus based Standards for the selection of health Measurement Instruments) checklist and the quality criteria of Terwee and colleagues, respectively.ResultsThe analysed information was extracted from three articles which had conducted studies on the prevalence of oropharyngeal dysphagia by self‐reported screening questionnaires, showing poor methodological quality and flaws in the methodological description to demonstrate its psychometric properties.ConclusionThis study did not find any self‐reported screening questionnaires for oropharyngeal dysphagia with suitable methodological quality and appropriate evidence in its psychometric properties for elders. Therefore, the self‐reported questionnaires within the diagnostic proposal require greater details in its process for obtaining valid and reliable evidence.
Effects of intermediate energy heavy‐ion irradiation on the microstructure of rutile TiO2 single crystal
Authors: Smith Kassiopeia A. , Savva Andreas I. , Wu Yaqiao , Tenne Dmitri A. , Butt Darryl P. , Xiong Hui , Wharry Janelle P. 
Published: April 2018

AbstractThis study reports the microstructure evolution of single crystal rutile TiO2 under 3 MeV Nb+ ion irradiation, with the irradiating ions incident on the {100} plane. A complex, multi‐layered microstructure evolution is observed with 4 distinct regions: (i) short‐range disorder in the first 60 nm below the specimen surface, (ii) dislocation loops oriented parallel to the incident ion beam direction, located along the increasing slope of the irradiation damage profile at ~60‐650 nm from the surface, (iii) loops oriented perpendicular to the incident ion beam direction, at depths encompassing the ion implantation and irradiation damage peaks ~650‐1250 nm, and (iv) a high density of nano‐scale atomic rearrangements with long‐range order, located at depths ~1250‐1750 nm. These results present evidence that multiple defect mechanisms occur during irradiation including ion channeling, nuclear stopping, and electronic stopping interactions as a function of depth and disorder accumulation.
Morphological Redescription ofOpalina undulataNie 1932 fromFejervarya limnochariswith Molecular Phylogenetic Study of Opalinids (Heterokonta, Opalinea)
Authors: Li Ming , Ponce‐Gordo Francisco , Grim J. Norman , Li Can , Zou Hong , Li Wenxiang , Wu Shangong , Wang Guitang 
Published: April 2018

AbstractThe redescription ofOpalina undulataNie 1932, collected from the rectum of the frogFejervarya limnocharis, is presented in this paper based on detailed morphological information and molecular data. Our results revealed that specimens collected from Diaocha Lake in late August were larger and had more nuclei than those collected from the same site in early May. We sequenced theirSSU rDNA‐ITS1‐5.8SrDNA‐ITS2‐LSU rDNA(5′ end) and found that they were completely identical, which means that the two populations belonged to the same species. These facts gave us a hint that body dimension and number of nuclei are not reliable taxonomic parameters for opalinids during their life cycle. Therefore, we recommended that the specific identification of opalinids based on morphological features should be carried out during seasons except spring. Meanwhile, our molecular phylogenetic analysis confirmed the monophyly of Opalinata. Within Opalinata, Opalinea were monophyletic with all opalinid species grouping together. Karotomorpha and Proteromonas did not group together confirming the paraphyly of Proteromonadea.
A new procedure for surface contamination of food products using absorbent paper
Authors: Tucci Patrizia , Sperandii Anna Franca , Salini Romolo , Centorotola Gabriella , Neri Diana , Iannetti Luigi , Migliorati Giacomo , Pomilio Francesco 
Published: April 2018

AbstractA new method was developed for artificial contamination of food products during challenge test studies, in products where superficial contamination is needed. Rinds of Gorgonzola cheese wheels were divided into quarters and then squares with 12 cm of side and contaminated with absorbent paper soaked with a bacterial suspension of Listeria monocytogenes left in contact with the surface of the blue‐veined cheese, in order to achieve homogenous contamination of the whole surface. To verify the performance of the method of contamination, after 24 hr L. monocytogenes was enumerated to evaluate surface contamination. With the method described, an average concentration of about 5 log10cfu/cm2 or MPN/cm2 was obtained starting from a contaminated suspension of 8 log10cfu/ml. The homogeneity of the contamination was demonstrated by the application of statistical tests.Practical applicationsChallenge tests are carried out to simulate contaminations as they happen during the processing and aging of cheeses, cured meats or ready‐to‐eat foods, for cross contamination studies, for applications of predictive microbiology, and to evaluate potential dragging of bacteria during the cutting of slices. In all cases, the inoculum should be applied on the product using the appropriate technique, in order to mimic natural contamination. This study reports a new method of contamination that allows the achievement of homogeneous microbial distribution on the whole flat surface of foods, using absorbent paper soaked with a bacterial suspension of Listeria monocytogenes. It was tested in the framework of challenge tests aimed to quantify the dragging of bacteria from Gorgonzola cheese rinds to paste during different processing steps. The procedure could be, however, profitably used also in other food products, when uniform surface contamination is required.
Development of colloidal gold‐based immunochromatographic strip test using two monoclonal antibodies for detection of Vibrio parahaemolyticus
Authors: Ding Chengchao , Li Jianwu , Liu Xiao , Liu Qing 
Published: April 2018

AbstractA rapid and sensitive colloidal gold‐based immunochromatographic test strip (ICTS) for the detection of Vibrio parahaemolyticus (VP) was developed. It was based on sandwich principle with two monoclonal antibodies (Mabs), namely H7 and C9. The Mab H7 gold nanoparticle (AuNPs‐Mab H7) conjugate was transferred onto a glass fiber pad as conjugate pad. Mab C9 containing 1% (M/V) bovine serum albumin and the goat anti‐mouse immunoglobulinG (IgG) antibody were sprayed onto a nitrocellulose membrane in strips at T and C line positions, respectively. The ICTS was assessed for the ability to detect VP, 50 μl aliquot of test sample was applied to the sample pad. The results were observable within 10 min after adding the sample. The sensitivity of the test was determined to be 104 CFU/ml. Detection of VP after 25‐week storage could be accomplished with similar sensitivities. The positive rate was 100% in seafood with the ICTS. The VP ICTS provided several advantages over other detection methods, including the short time, low cost, convenient to use, and not requiring sophisticated equipment. Furthermore, the results could be imaged and transformed into a two‐dimensional bar code by using a smart cell phone for more vividly, clearly and permanently being observed.Practical applicationsDuring the past two decades, Vibrio parahaemolyticus (VP) has been one of the most common causes of the bacterial foodborne outbreaks, which caused abdominal cramps, vomiting, nausea, headaches, fever, and chills. Therefore, the detection of VP is crucial to public food safety. This study obtained two different monoclonal antibodies (Mabs; Mab H7 and C9) of VP with high specificity and no cross‐reactions were found with other foodborne pathogens. The AuNPs‐based immunochromatographic test strip (ICTS) was developed with the Mabs (Mab H7 and C9) and the ICTS was evaluated with high sensitivity, high specificity, low cost, and rapid speed for VP detection. The accuracy rate of immunochromatographic strip for detection VP was 100% in seafood samples.
SIP1 participates in regulation of flowering time in rice by recruiting OsTrx1 to Ehd1
Authors: Jiang Pengfei , Wang Shiliang , Zheng Han , Li Hao , Zhang Fei , Su Yanhua , Xu Zuntao , Lin Haiyan , Qian Qian , Ding Yong 
Published: April 2018

Summary

Flowering time (heading date) in rice (Oryza sativa) is an important agronomic trait that determines yield. The levels of histone H3 lysine 4 trimethylation (H3K4me3) modulated by TRITHORAX‐like proteins regulate gene transcription, flowering time and environmental stress responses. However, plant TRITHORAX‐like proteins have no known DNA‐binding domain, and therefore the mechanism that gives sequence specificity to these proteins remains unclear.

Here, we show that the rice TRITHORAX‐like protein OsTrx1 is recruited to its target, Early heading date 1 (Ehd1), by the C2H2 zinc finger protein SDG723/OsTrx1/OsSET33 Interaction Protein 1 (SIP1).

SIP1 binds to the promoter of Ehd1 and interacts with OsTrx1. Mutations in SIP1 led to a late heading date under long‐day and short‐day conditions. Defects in OsTrx1 or SIP1 led to reduced H3K4me3 levels at Ehd1, thus reducing Ehd1 expression.

Together, our results show that the transcription factor SIP1 interacts with OxTrx1, allowing OsTrx1 to specifically target Ehd1, altering H3K4me3 levels, increasing Ehd1 expression and thereby promoting flowering.