bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of student use of videos to support learning in a simulation laboratory course: A perception and analytics approach
Authors: Botelho Michael G. 
Published: September 2019

AbstractAimThis paper evaluates the use of online video learning materials used for a simulation laboratory course for 2 consecutive cohorts of students using an evaluation and analytics approach.Methods100 online video clips were created to support students’ learning before, during and after the scheduled simulation laboratory teaching sessions in a fixed prosthodontics course. Videoed online presentations included screen‐captured PowerPoint presentations, simulation laboratory psychomotor and clinical skills demonstrations, individual student case consultations and whole‐class worksheet debriefings. Data files and access data were analyzed for 2 consecutive cohorts of 4th year students. An evaluation questionnaire was administered on the 2015 cohort.ResultsFeedback on learning resources were strongly positive. 100% of students reported that the videos helped in their learning, preparation for simulation laboratory classes, to refresh their memory prior to clinical care, prepare for the clinical competency test and prepare for examinations. In total, 4689 videos were accessed, 35% by class 2015 and 65% by 2016. 73% of these were watched during the simulation laboratory course, 13% were watched 2‐3 weeks before examinations and 14% during the remainder of the year.ConclusionVideos were reported to support student learning and were valued for a range of learning needs. However, significant differences between student consumption and strategies need to be designed to engage low consumers.
Clinical outcomes of patients with bilateral anterior disc displacement without reduction and erosive change of the temporomandibular joint after performance of unilateral arthrocentesis and stabilisation splint therapy
Authors: Heo Hyun‐A , Yoon Hyun‐Joong 
Published: September 2019

AbstractThe efficacy of a combination treatment of arthrocentesis and stabilisation splint for patients with bilateral anterior disc displacement without reduction (ADDWoR) and erosive change of the TMJ remains controversial. To evaluate clinical outcomes of patients with ADDWoR and erosive change of the TMJ after performance of unilateral arthrocentesis and stabilisation splint therapy. A retrospective study of 44 patients (37 females, 7 males, mean age of 34 years) with bilateral ADDWoR and erosive change of the TMJ were included in this study. Their clinical outcomes before and after arthrocentesis and stabilisation splint therapy were compared. Evaluation criteria were as follows: (a) Maximal mouth opening (MMO); (b) Right and left maximal lateral movement (RLM, LLM) and maximal protrusive movement (PM); (c) Visual analog scale (VAS) pain score during MMO, RLM, LLM and PM; and (d) VAS pain score during palpation of masticatory muscles. Wilcoxon signed‐rank test, Mc Nemar test and paired t test were used for statistical analysis. Differences in VAS pain score between arthrocentesis and non‐arthrocentesis sites were not statistically significant except MMO and LLM (P < .05) after 6 months. Differences in mean VAS pain scores for all variables between before arthrocentesis and 6 months follow‐up in the arthrocentesis site were statistically significant. (P < .01). Unilateral arthrocentesis on more symptomatic TMJ and subsequent stabilisation splint therapy was highly successful for pain and achievement of normal range of mandibular movements in patients with both ADDWoR and bony change.
Effect of Screw Channel Angulation on Reverse Torque Values of Dental Implant Abutment Screws
Authors: Hu Eric , Petrich Anton , Imamura Glen , Hamlin Christopher 
Published: September 2019

AbstractPurposeTo compare the reverse torque values (RTVs) of abutment screws tightened from three different angles.Materials and MethodsImplant abutment screws (n = 48), abutments (3), and regular platform implant analogs (3) were divided into three angulation groups (n = 16/group). Custom guides of 0°, 10°, and 20° were fabricated to verify driver angulation. The implant components for each group were assembled and all screws torqued to 35 Ncm using a universal screwdriver in a manual torque wrench at the appropriate angle. Torque was reapplied 10 minutes after initial torque. A digital gauge was then used to measure reverse torque at a position parallel (0°) to the implant analog. RTVs were recorded and compared using one‐way ANOVA and Tukey HSD post‐hoc comparisons (α = 0.05).ResultsAll mean RTVs fell below the targeted torque value of 35Ncm, with some values in each angulation group 10% below of the target value. Mean RTVs in descending order from targeted torque value were: 10° group = 32.07 ± 0.97 Ncm, 0° group = 31.16 ± 1.12 Ncm, and 20° group = 30.08 ± 0.88 Ncm. One‐way ANOVA revealed significant differences between angulation groups (F = 15.954, p < 0.001). Tukey HSD post hoc comparisons revealed that the mean RTVs of the three angulation groups were significantly different from each other (0° vs. 10°: p = 0.033; 0° vs. 20°: p = 0.011; 10° vs. 20°: p < 0.001).ConclusionsAll RTVs did not reach the targeted torque value of 35 Ncm. Mean screw RTVs were significantly influenced by screwdriver insertion angulation.
Evaluation of benazepril in cats with heart disease in a prospective, randomized, blinded, placebo‐controlled clinical trial
Authors: King Jonathan N. , Martin Mike , Chetboul Valérie , Ferasin Luca , French Anne T. , Strehlau Günther , Seewald Wolfgang , Smith Sarah G. W. , Swift Simon T. , Roberts Susan L. , Harvey Andrea M. , Little Christopher J. L. , Caney Sarah M. A. , Simpson Kerry E. , Sparkes Andrew H. , Mardell Eleanor J. , Bomassi Eric , Muller Claude , Sauvage John P. , Diquélou Armelle , Schneider Matthias A. , Brown Laurence J. , Clarke David D. , Rousselot Jean‐Francois 
Published: September 2019

AbstractBackgroundHeart disease is an important cause of morbidity and mortality in cats, but there is limited evidence of the benefit of any medication.HypothesisThe angiotensin‐converting enzyme inhibitor benazepril would delay the time to treatment failure in cats with heart disease of various etiologies.AnimalsOne hundred fifty‐one client‐owned cats.MethodsCats with heart disease, confirmed by echocardiography, with or without clinical signs of congestive heart failure, were recruited between 2002 and 2005 and randomized to benazepril or placebo in a prospective, multicenter, parallel‐group, blinded clinical trial. Benazepril (0.5‐1.0 mg/kg) or placebo was administered PO once daily for up to 2 years. The primary endpoint was treatment failure. Analyses were conducted separately for all‐cause treatment failure (main analysis) and heart disease‐related treatment failure (supportive analysis).ResultsNo benefit of benazepril versus placebo was detected for time to all‐cause treatment failure (P= .42) or time to treatment failure related to heart disease (P= .21). Hazard ratios (95% confidence interval [CI]) from multivariate analysis for benazepril compared with placebo were 1.00 (0.57‐1.74) for all‐cause failure, and 0.99 (0.50‐1.94) for forward selection and 0.93 (0.48‐1.81) for bidirectional selection models for heart disease‐related failure. There were no significant differences between groups over time after administration of the test articles in left atrium diameter, left ventricle wall thickness, quality of life scores, adverse events, or plasma biochemistry or hematology variables.Conclusions and Clinical RelevanceBenazepril was tolerated well in cats with heart disease, but no evidence of benefit was detected.
Responses of peatland vegetation to 15‐year water level drawdown as mediated by fertility level
Authors: Kokkonen Nicola A. K. , Laine Anna Maria , Laine Jukka , Vasander Harri , Kurki Kirsi , Gong Jinnan , Tuittila Eeva‐Stiina 
Published: September 2019

AbstractQuestionsPeatland ecosystems are a globally important carbon storage that is predicted to turn into a carbon source due to water level drawdown (WLD) associated with climate change. The predictions assume stable plant communities but how realistic is this assumption? If the vegetation is not stable, what are the nature and rate of changes?LocationPeatland complex in Southern Finland.MethodsWe conducted a water level drawdown (WLD of ~10 cm) experiment over 17 years in three peatland types differing in their fertility. On each peatland type, we included an adjacent forestry drained (FD, with water table ca. 40 cm lower than in control) area for comparison.ResultsPeatland type had a clear impact on the response to WLD: at the ecosystem level, the two minerotrophic fens underwent rapid species turnover, while the vegetation in nutrient‐poor bog was more resilient to change. In nutrient‐rich sites, WLD initiated tree canopy development and created understorey conditions that strengthened impact of WLD. In nutrient‐poor site, tree establishment was seen only in the FD area. In addition to high nutrient level, high wetness accelerated change at the plant community level, where we found three types of responses: accelerating change, decelerating change, and stability. Succession resulted in an overall loss of community heterogeneity.ConclusionsInteraction between hydrology, nutrient availability, and biological factors in boreal peatlands is important: the drop in water table required to achieve the shift from open peatland to forested system is inversely proportional to the nutrient level of the system. The results suggest that predictive models of peatland functions under climate change should consider compositional change for fens and their diverse plant communities but are more realistic for bogs. The response of bog vegetation to climate change may, however, be more dependent on changes in rainfall regime and therefore needs to be further addressed.
Reimagining the relationship between food sovereignty and intellectual property for plants: Lessons from Ecuador and Nepal
Authors: Jefferson David J. , Adhikari Kamalesh 
Published: September 2019

AbstractThe concept of food sovereignty is regularly conceived as one side of a binary. Thus, scholars frequently juxtapose food sovereignty—as embodied in small‐scale, customary, or peasant agriculture—against large‐scale, industrial, and global modes of food production. The logic of this dichotomy suggests that the realization of food sovereignty is incompatible with the recognition of intellectual property for plants and seeds. In contrast, we argue that food sovereignty and intellectual property are not necessarily mutually exclusive concepts. Instead, food sovereignty activists and lawmakers alike are reimagining intellectual property to move beyond a focus on exclusive ownership, thus deploying it in novel ways. Our argument draws on extensive fieldwork, based on which we relate the experiences of two case study countries, namely Ecuador and Nepal. We describe how these countries recently embedded rights related to food sovereignty in reformed constitutional frameworks. We also evaluate how these novel constitutional food sovereignty rights shaped the making of other national laws in Ecuador and Nepal, including frameworks whose purpose is to protect plant varieties as intellectual property. Throughout the article, we demonstrate that countries can both promote food sovereignty and protect plant varieties as intellectual property. One way that governments can achieve this goal is to ensure that all relevant laws and policies—including those which relate to intellectual property for plant varieties, seed certification, and commercialization, and access and use of native genetic resources—are tailored to the realities of local food and seed systems.
Assessing student expectations and perceptions of a short‐term international service‐learning experience
Authors: Knecht Linda D’Appolonia , Wilson Kristi Jo , Linton Mary Elizabeth , Koonmen Jamie M. , Johns Edgar F. 
Published: September 2019

AbstractObjectivesDespite nursing students’ need for cultural education, few studies have measured what students expect from international service‐learning experiences and how their perceptions of the actual experience compare to these expectations. To increase understanding of global nursing experiences, the purpose of this study was to examine the similarities and differences between nursing students’ anticipated (pre‐travel) personal and professional developmental expectations and reported (posttravel) personal and developmental outcomes.DesignThis study employed a mixed descriptive research design. Quantitative data was secured through survey methodology. Written responses to open‐ended questions provided qualitative data for analysis.SampleBetween 2012 and 2017, 43 undergraduate and graduate nursing students at a Midwestern university completed surveys and narratives about their participation in an international service‐learning course in Kenya.ResultsStudents’ anticipated learning was achieved through their international experiences. Participants also experienced personal growth, professional development, cultural competency enhancement, and transformation from the educational experience. They also described how their experiences would change their personal and professional lives.ConclusionThe depth and breadth of the growth and learning described by students is consistent with the expectations of high‐impact educational practices.
DermaTOP Blue and Antera 3D as methods to assess cosmetic solutions targeting eyelid sagging
Authors: Hurley Sarah , Messaraa Cyril , O’Connor Carla , Metois Adeline , Walsh Melissa , Mc Namee Deirdre , Mansfield Anna , Robertson Nicola , Doyle Leah , Mavon Alain 
Published: September 2019

AbstractBackgroundAs the eye contour ages, the skin on the lid becomes lax often causing a voluminous protrusion where the superior palpebral sulcus begins to sag onto the upper eyelid. This sagging feature may present a novel anti‐ageing target for cosmetic products when treating the eye area. A quantitative method to evaluate the volume of this sagging feature has not been previously established. We investigate the use of the DermaTOP fringe projector and Antera 3D Camera to this end.MethodsEyelid topographic measurements were collected on 20 female volunteers aged 50‐75 years with the DermaTOP and Antera 3D. The DermaTOP and Antera 3D measurements were assessed for reproducibility and product effect detection capabilities.ResultsThe DermaTOP and Antera 3D successfully measured sagging feature volume, demonstrated reproducibility of measurement and furthermore were suitably sensitive to allow for detection of sagging feature volume reduction after a single application of aqueous tightening serum. DermaTOP parameters were found to moderately correlated with the Antera 3D parameters.ConclusionBoth the DermaTOP and Antera 3D allow for quantitative measurement of eyelid sagging feature volume and in‐turn permit evaluation of anti‐ageing cosmetic preparations targeting the eyelid.
Structure–function analysis of ZAR1 immune receptor reveals key molecular interactions for activity
Authors: Baudin Maël , Schreiber Karl J. , Martin Eliza C. , Petrescu Andrei J. , Lewis Jennifer D. 
Published: September 2019

SummaryNLR (nucleotide‐binding [NB] leucine‐rich repeat [LRR] receptor) proteins are critical for inducing immune responses in response to pathogen proteins, and must be tightly modulated to prevent spurious activation in the absence of a pathogen. The ZAR1 NLR recognizes diverse effector proteins from Pseudomonas syringae, including HopZ1a, and Xanthomonas species. Receptor‐like cytoplasmic kinases (RLCKs) such as ZED1, interact with ZAR1 and provide specificity for different effector proteins, such as HopZ1a. We previously developed a transient expression system in Nicotiana benthamiana that allowed us to demonstrate that ZAR1 function is conserved from the Brassicaceae to the Solanaceae. Here, we combined structural modelling of ZAR1, with molecular and functional assays in our transient system, to show that multiple intramolecular and intermolecular interactions modulate ZAR1 activity. We identified determinants required for the formation of the ZARCC oligomer and its activity. Lastly, we characterized intramolecular interactions between ZAR1 subdomains that participate in keeping ZAR1 immune complexes inactive. This work identifies molecular constraints on immune receptor function and activation.
JAZ4 is involved in plant defense, growth, and development in Arabidopsis
Authors: Oblessuc Paula R. , Obulareddy Nisita , DeMott Logan , Matiolli Cleverson C. , Thompson Blaine K. , Melotto Maeli 
Published: September 2019

SummaryJasmonate zim‐domain (JAZ) proteins comprise a family of transcriptional repressors that modulate jasmonate (JA) responses. JAZ proteins form a co‐receptor complex with the F‐box protein coronatine insensitive1 (COI1) that recognizes both jasmonoyl‐l‐isoleucine (JA‐Ile) and the bacterial‐produced phytotoxin coronatine (COR). Although several JAZ family members have been placed in this pathway, the role of JAZ4 in this model remains elusive. In this study, we observed that the jaz4‐1 mutant of Arabidopsis is hyper‐susceptible to Pseudomonas syringae pv. tomato (Pst) DC3000, while Arabidopsis lines overexpressing a JAZ4 protein lacking the Jas domain (JAZ4∆Jas) have enhanced resistance to this bacterium. Our results show that the Jas domain of JAZ4 is required for its physical interaction with COI1, MYC2 or MYC3, but not with the repressor complex adaptor protein NINJA. Furthermore, JAZ4 degradation is induced by COR in a proteasome‐ and Jas domain‐dependent manner. Phenotypic evaluations revealed that expression of JAZ4∆Jas results in early flowering and increased length of root, hypocotyl, and petiole when compared with Col‐0 and jaz4‐1 plants, although JAZ4∆Jas lines remain sensitive to MeJA‐ and COR‐induced root and hypocotyl growth inhibition. Additionally, jaz4‐1 mutant plants have increased anthocyanin accumulation and late flowering compared with Col‐0, while JAZ4∆Jas lines showed no alteration in anthocyanin production. These findings suggest that JAZ4 participates in the canonical JA signaling pathway leading to plant defense response in addition to COI1/MYC‐independent functions in plant growth and development, supporting the notion that JAZ4‐mediated signaling may have distinct branches.
Cooling of Particulate Solids and Fluid in a Moving Bed Heat Exchanger
Authors: Turkyilmazoglu Mustafa 
Published: September 2019

Abstract
The current technical brief is to analytically solve the coupled energy equations governing the thermal phenomenon of particulate solids and cooling fluid present inside moving bed heat exchangers constructed via a parallel plate system. The prime concern is to analytically evaluate the cooling effects of a heat sink (absorbent) placed within the media on the particulate and fluid and hence to obtain the relevant temperature fields for the latter. In the absence of such a source term, the solutions collapse onto the recent literature. Results clearly demonstrate how an effective cooling can be achieved with a heat sink mounted on industrial moving bed heat exchangers. Particularly, the existence of an energy sink results in cooler solid particles as compared to the flowing fluid.
Organizational Failure Analysis for Industrial Safety
Authors: Robert Taylor J. 
Published: September 2019

Abstract
Organizational and management errors and failures represent a very significant causal influence in industrial accidents. A method, organizational failure analysis (OFA) is described for in-depth identification of organizational deficiencies and failures that can lead to accidents. The method was developed on the basis of an extensive data collection from safety management audits, accident and incident investigations, and emergency training exercises led by the author over a period of 26 years. From these data, a number of models of organizational performance and management behavior are derived. The models allow a semi-automated application of the method, which is important for the application to large organizations. The method is described with examples, and the results of several studies aimed at validating the method are given.
Adaptive Control of Microgas Turbine for Engine Degradation Compensation
Authors: Zaccaria Valentina , Ferrari Mario L. , Kyprianidis Konstantinos 
Published: September 2019

Abstract
Microgas turbine (MGT) engines in the range of 1–100 kW are playing a key role in distributed generation applications, due to the high reliability and quick load following that favor their integration with intermittent renewable sources. Micro-combined heat and power (CHP) systems based on gas turbine technology are obtaining a higher share in the market and are aiming at reducing the costs and increasing energy conversion efficiency. An effective control of system operating parameters during the whole engine lifetime is essential to maintain desired performance and at the same time guarantee safe operations. Because of the necessity to reduce the costs, fewer sensors are usually available than in standard industrial gas turbines, limiting the choice of control parameters. This aspect is aggravated by engine aging and deterioration phenomena that change operating performance from the expected one. In this situation, a control architecture designed for healthy operations may not be adequate anymore, because the relationship between measured parameters and unmeasured variables (e.g., turbine inlet temperature (TIT) or efficiency) varies depending on the level of engine deterioration. In this work, an adaptive control scheme is proposed to compensate the effects of engine degradation over the lifetime. Component degradation level is monitored by a diagnostic tool that estimates performance variations from the available measurements; then, the information on the gas turbine health condition is used by an observer-based model predictive controller to maintain the machine in a safe range of operation and limit the reduction in system efficiency.
A Methodology to Assess Subregional Geometric Complexity for Tetralogy of Fallot Patients
Authors: Louvelle Leslie M. , Doyle Matthew G. , Van Arsdell Glen S. , Amon Cristina H. 
Published: September 2019

Abstract
During surgical repair of tetralogy of fallot (TOF), pulmonary valve preservation (preservative repair) has demonstrated improved long-term outcomes compared to repairs that incise into the valve annulus (nonpreservative repair). Given the influence of geometry on hemodynamics, the success of preservative repair may be linked to the suitability of the preoperative patient geometry. However, the specific patient anatomies that may be predisposed to successful preservative repair are unknown due to significant interpatient variability in right ventricular outflow tract (RVOT) and pulmonary artery geometries, as well as the limitations in current methods of subregional geometric analysis. As a first step toward understanding the link between geometry and hemodynamics in TOF patients at a subregion level, we characterize the TOF geometry from the right ventricular infundibulum (INF) to the left and right pulmonary arteries. Our process consists of segmentation of magnetic resonance (MR) images and analysis of cross-sectional slices of the geometries along the centerlines. For the INF, main, left, and right pulmonary arteries individually, we quantify geometric parameters important in determining hemodynamic characteristics such as flow separation and recirculation, which can influence the degree of regurgitation. Specifically, we calculate the diameter along the subregion length, the average diameter, length, and tortuosity for each segment, as well as the bifurcation, left pulmonary artery (LPA) and right pulmonary artery (RPA) branch angles. This approach enables direct geometric comparisons within and among patients and allows for observation of the range in anatomic presentation. We have applied this approach to a dataset of 11 postoperative TOF patients, repaired with both preservative and nonpreservative surgical techniques.