bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survival Comparisons Between Early Male and Female Breast Cancer Patients
Authors: Wang Kang , Wang Qiu-Juan , Xiong Yong-Fu , Shi Yang , Yang Wen-Jing , Zhang Xiang , Li Hong-Yuan 
Published: June 2018

AbstractWe aimed to compare the overall survival (OS) and standardized mortality rate (SMR) of the male breast cancer (MBC) with female breast cancer (FBC) after propensity score matching. Based on the Surveillance, Epidemiology, and End Results (SEER), the early breast cancer patients (T1–2N0–2M0) were extracted from 1998–2007. This study included 1,111 and 2,151 patients with early MBC and FBC, respectively, whose clinicopathological characteristics were well balanced. At a mean follow-up time of 97 months, 10-year OS rate was 58.3% in the MBC group and 68.7% in the FBC (log-rank test, P < 0.001; hazard ratio (HR) = 1.45, 95% confidence interval (CI) = 1.29 to 1.64). Adjusted HR for OS between MBC and FBC were revealed from propensity score matched-multivariable Cox proportional hazards models (HR = 1.53, 95% CI = 1.35 to 1.73). Similar adjusted SMRs between MBC and FBC ((SMR = 1.98, 95% CI = 1.83,2.14) for FBC and (SMR = 2.07, 95% CI = 1.88–2.28) for MBC) were observed. The nomogram was constructed for FBC, and predicted probabilities were generally good (C-index = 0.71), whose area under curve is higher than TNM stage classification (0.74 vs 0.62). OS was significantly decreased among early MBC patients compared with FBC, but similar SMRs and its trends by age groups were observed between MBC and FBC except for young patients.
Fabrication and thermal properties of tetradecanol/graphene aerogel form-stable composite phase change materials
Authors: Mu Boyuan , Li Min 
Published: June 2018

AbstractIn this study, tetradecanol/graphene aerogel form-stable composite phase change materials were prepared by physical absorption. Two kinds of graphene aerogels were prepared using vitamin C and ethylenediamine to enhance the thermal conductivity of tetradecanol and prevent its leakage during phase transition. The form-stable composite phase change material exhibited excellent thermal energy storage capacity. The latent heat of the tetradecanol/graphene aerogel composite phase change materials with 5 wt.% graphene aerogel was similar to the theoretical latent heat of pure tetradecanol. The thermal conductivity of the tetradecanol/graphene aerogel composite phase change material improved gradually as the graphene aerogel content increased. The prepared tetradecanol/graphene aerogel composite phase change materials exhibited good thermal reliability and thermal stability, and no chemical reaction occurred between tetradecanol and the graphene aerogel. In addition, the latent heat and thermal conductivity of the tetradecanol/ethylenediamine-graphene aerogel composites were higher than those of tetradecanol/vitamin C-graphene aerogel composites, and the flexible shape of the ethylenediamine-graphene aerogel is suitable for application of the tetradecanol/ethylenediamine-graphene aerogel composite.
NMR studies of excluded volume interactions in peptide dendrimers
Authors: Sheveleva Nadezhda N. , Markelov Denis A. , Vovk Mikhail A. , Mikhailova Maria E. , Tarasenko Irina I. , Neelov Igor M. , Lähderanta Erkki 
Published: June 2018

AbstractPeptide dendrimers are good candidates for diverse biomedical applications due to their biocompatibility and low toxicity. The local orientational mobility of groups with different radial localization inside dendrimers is important characteristic for drug and gene delivery, synthesis of nanoparticles, and other specific purposes. In this paper we focus on the validation of two theoretical assumptions for dendrimers: (i) independence of NMR relaxations on excluded volume effects and (ii) similarity of mobilities of side and terminal segments of dendrimers. For this purpose we study 1H NMR spin-lattice relaxation time, T1H, of two similar peptide dendrimers of the second generation, with and without side fragments in their inner segments. Temperature dependences of 1/T1H in the temperature range from 283 to 343 K were measured for inner and terminal groups of the dendrimers dissolved in deuterated water. We have shown that the 1/T1H temperature dependences of inner groups for both dendrimers (with and without side fragments) practically coincide despite different densities of atoms inside these dendrimers. This result confirms the first theoretical assumption. The second assumption is confirmed by the 1/T1H temperature dependences of terminal groups which are similar for both dendrimers.
Electrochemical properties of novel FeV2O4 as an anode for Na-ion batteries
Authors: Maggay Irish Valerie B. , De Juan Lyn Marie Z. , Lu Jeng-Shin , Nguyen Mai Thanh , Yonezawa Tetsu , Chan Ting-Shan , Liu Wei-Ren 
Published: June 2018

AbstractSpinel based transition metal oxide – FeV2O4 is applied as a novel anode for sodium-ion battery. The electrochemical tests indicate that FeV2O4 is generally controlled by pseudo-capacitive process. Using cost-effective and eco-friendly aqueous based binders, Sodium-Carboxymethylcellulose/Styrene butadiene rubber, a highly stable capacity of ~97 mAh∙g−1 is obtained after 200 cycles. This is attributed to the strong hydrogen bonding of carboxyl and hydroxyl groups indicating superior binding with the active material and current collector which is confirmed by the ex-situ cross-section images of the electrode. Meanwhile, only ~27 mAh∙g−1 is provided by the electrode using poly(vinylidene difluoride) due to severe detachment of the electrode material from the Cu foil after 200 cycles. The obtained results provide an insight into the possible applications of FeV2O4 as an anode material and the use of water-based binders to obtain highly stable electrochemical tests for sodium-ion battery.
Enhanced non-Markovian behavior in quantum walks with Markovian disorder
Authors: Kumar N. Pradeep , Banerjee Subhashish , Chandrashekar C. M. 
Published: June 2018

AbstractNon-Markovian quantum effects are typically observed in systems interacting with structured reservoirs. Discrete-time quantum walks are prime example of such systems in which, quantum memory arises due to the controlled interaction between the coin and position degrees of freedom. Here we show that the information backflow that quantifies memory effects can be enhanced when the particle is subjected to uncorrelated static or dynamic disorder. The presence of disorder in the system leads to localization effects in 1-dimensional quantum walks. We shown that it is possible to infer about the nature of localization in position space by monitoring the information backflow in the reduced system. Further, we study other useful properties of quantum walk such as entanglement, interference and its connection to quantum non-Markovianity.
Establishment of a novel mouse xenograft model of human uterine leiomyoma
Authors: Suzuki Yusuke , Ii Masaaki , Saito Takashi , Terai Yoshito , Tabata Yasuhiko , Ohmichi Masahide , Asahi Michio 
Published: June 2018

AbstractUterine leiomyoma is the most common benign tumour in women, and an appropriate animal model for leiomyoma would be useful for exploring new therapeutic strategies. Therefore, we have been challenged to develop a new simple mouse model for human leiomyoma. Leiomyoma tissues were harvested from myomas resected by different surgical procedures with or without gonadotropin-releasing hormone agonist (GnRHa) treatment and were subcutaneously implanted into BALB/c nude mice with an estradiol/progesterone-releasing pellet. The implanted leiomyoma tissues that were obtained from the marginal site of large myomas resected by abdominal myomectomy with GnRHa treatment exhibited sufficient tumour growth in the transplanted mice. The leiomyomas that were treated with GnRHa highly expressed the estrogen/progesterone receptor genes, insulin-like growth factor 2 (IGF2) and embryonic smooth muscle myosin heavy chain (SMemb), which suggests that these factors are critical in the establishment of a mouse model of growing leiomyoma. As a result, this model will be useful for the development of new therapeutic strategies.
Heterogeneity of interactions of microbial communities in regions of Taihu Lake with different nutrient loadings: A network analysis
Authors: Cao Xinyi , Zhao Dayong , Xu Huimin , Huang Rui , Zeng Jin , Yu Zhongbo 
Published: June 2018

AbstractTo investigate the differences in the interactions of microbial communities in two regions in Taihu Lake with different nutrient loadings [Meiliang Bay (MLB) and Xukou Bay (XKB)], water samples were collected and both intra- and inter-kingdom microbial community interactions were examined with network analysis. It is demonstrated that all of the bacterioplankton, microeukaryotes and inter-kingdom communities networks in Taihu Lake were non-random. For the networks of bacterioplankton and inter-kingdom community in XKB, higher clustering coefficient and average degree but lower average path length indexes were observed, indicating the nodes in XKB were more clustered and closely connected with plenty edges than those of MLB. The bacterioplankton and inter-kingdom networks were considerably larger and more complex with more module hubs and connectors in XKB compared with those of MLB, whereas the microeukaryotes networks were comparable and had no module hubs or connectors in the two lake zones. The phyla of Acidobacteria, Cyanobacteria and Planctomycetes maintained greater cooperation with other phyla in XKB, rather than competition. The relationships between microbial communities and environmental factors in MLB were weaker. Compared with the microbial community networks of XKB, less modules in networks of MLB were significantly correlated with total phosphorous and total nitrogen.
Familial hypercholesterolemia in very young myocardial infarction
Authors: Li Sha , Zhang Hui-Wen , Guo Yuan-Lin , Wu Na-Qiong , Zhu Cheng-Gang , Zhao Xi , Sun Di , Gao Xiong-Yi , Gao Ying , Zhang Yan , Qing Ping , Li Xiao-Lin , Sun Jing , Liu Geng , Dong Qian , Xu Rui-Xia , Cui Chuan-Jue , Li Jian-Jun 
Published: June 2018

AbstractFamilial hypercholesterolemia (FH) is one of the most common causes of premature myocardial infarction (MI). However, The patterns of FH remained unrecognized in clinical care, especially in very young patients (VYPs, ≤35 years) with MI. The present study enrolled a total of 1,093 VYPs (≤35 years) presenting a first MI. Clinical diagnosis of FH was made using Dutch Lipid Clinic Network criteria. Coronary severity was assessed by Gensini score (GS). Patients were followed for a median of 40-months with cardiac death, stroke, MI, post-discharge revascularization or unstable angina as primary endpoints. The detected rates of definite/probable FH were 6.5%. The prevalence reached up to 10.3% in patients ≤25 years. The FH had similar levels of comorbidities but was younger, more likely to be very high risk (VHR) and had higher GS (p < 0.05) than unlikely FH. Notably, the FH on prior lipid-lowering medication presented a lower GS compared to those untreated. Differences in event rates were similar in FH as unlikely FH (11.8% vs. 8.1%, adjusted hazard ratio 1.35 [0.64–2.86], p = 0.434) but patients on treatment improved outcome (6.5% vs. 10.5%, adjusted hazard ratio 0.35[0.13–0.95], p = 0.039). The early identification and treatment might be critical to reduce cardiovascular risk in VYPs with MI.
Calcium leaching behavior of cementitious materials in hydrochloric acid solution
Authors: Yang Huashan , Che Yujun , Leng Faguang 
Published: June 2018

AbstractThe calcium leaching behavior of cement paste and silica fume modified calcium hydroxide paste, exposed to hydrochloric acid solution, is reported in this paper. The kinetic of degradation was assessed by the changes of pH of hydrochloric acid solution with time. The changes of compressive strength of specimens in hydrochloric acid with time were tested. Hydration products of leached specimens were also analyzed by X-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric (TG), and atomic force microscope (AFM). Tests results show that there is a dynamic equilibrium in the supply and consumption of calcium hydroxide in hydrochloric acid solution, which govern the stability of hydration products such as calcium silicate hydrate (C-S-H). The decrease of compressive strength indicates that C-S-H are decomposed due to the lower concentration of calcium hydroxide in the pore solution than the equilibrium concentration of the hydration products. Furthermore, the hydration of unhydrated clinker delayed the decomposition of C-S-H in hydrochloric acid solution due to the increase of calcium hydroxide in pore solution of cementitious materials.
Linkage disequilibrium in Brazilian Santa Inês breed, Ovis aries
Authors: Alvarenga Amanda Botelho , Rovadoscki Gregori Alberto , Petrini Juliana , Coutinho Luiz Lehmann , Morota Gota , Spangler Matthew L. , Pinto Luís Fernando Batista , Carvalho Gleidson Giordano Pinto , Mourão Gerson Barreto 
Published: June 2018

AbstractFor genomic selection to be successful, there must be sufficient linkage disequilibrium between the markers and the causal mutations. The objectives of this study were to evaluate the extent of LD in ovine using the Santa Inês breed and to infer the minimum number of markers required to reach reasonable prediction accuracy. In total, 38,168 SNPs and 395 samples were used. The mean LD between adjacent marker pairs measured by r2 and |D′| were 0.166 and 0.617, respectively. LD values between adjacent marker pairs ranged from 0.135 to 0.194 and from 0.568 to 0.650 for r2 for |D′| across all chromosomes. The average r2 between all pairwise SNPs on each chromosome was 0.018. SNPs separated by between 0.10 to 0.20 Mb had an estimated average r2 equal to 0.1033. The identified haplotype blocks consisted of 2 to 21 markers. Moreover, estimates of average coefficients of inbreeding and effective population size were 0.04 and 96, respectively. LD estimated in this study was lower than that reported in other species and was characterized by short haplotype blocks. Our results suggest that the use of a higher density SNP panel is recommended for the implementation of genomic selection in the Santa Inês breed.
Characterization of ladybird Henosepilachna vigintioctopunctata transcriptomes across various life stages
Authors: Zhang Qi-Lin , Wang Feng , Guo Jun , Deng Xian-Yu , Chen Jun-Yuan , Lin Lian-Bing 
Published: June 2018

AbstractHenosepilachna vigintioctopunctata is a vegetable pest that has spread worldwide. It belongs to the Coccinellidae family, whose members exhibit remarkable diversity, both in terms of their diets and the colored spots that appear on the elytra in the adult stage. Transcriptomic data from H. vigintioctopunctata at different life stages would be useful for further investigating the genetic basis of this dietary diversity and the formation of the colored spots in ladybird beetles, as well as revealing the population dynamics of H. vigintioctopunctata, which could be useful in pest control. Here, we generated a comprehensive RNA-seq data set (a total of ~24 Gb of clean data) for H. vigintioctopunctata by sequencing samples collected at different life stages. We characterized the transcriptomes of each of the four life stages (egg, larva, pupa, adult) and generated a high-coverage pool by combining all the RNA-seq reads. Furthermore, we identified a catalog of simple sequence repeat (SSR) markers. This represents the first study to collect transcriptome data from all life stages of a ladybird beetle.
A simple flash carbonization route for conversion of biomass to porous carbons with high CO2 storage capacity
Authors: Hirst Edward A. , Taylor Alison , Mokaya Robert 
Published: June 2018

Flash carbonization is an attractive yet simple route for the preparation of biomass (sawdust) derived carbons that exhibit attractive CO2 uptake of up to 5.0 mmol g−1 (at 25 °C and 1 bar), and exceptional working capacity for pressure or vacuum swing adsorption processes under simulated flue gas conditions.
Receptive Language Skills in Slovak-Speaking Children With Intellectual Disability: Understanding Words, Sentences, and Stories
Authors: Polišenská Kamila , Kapalková Svetlana , Novotková Monika 
Published: June 2018

PurposeThe study aims to describe receptive language skills in children with intellectual disability (ID) and to contribute to the debate on deviant versus delayed language development. This is the 1st study of receptive skills in children with ID who speak a Slavic language, providing insight into how language development is affected by disability and also language typology.MethodTwenty-eight Slovak-speaking children participated in the study (14 children with ID and 14 typically developing [TD] children matched on nonverbal reasoning abilities). The children were assessed by receptive language tasks targeting words, sentences, and stories, and the groups were compared quantitatively and qualitatively.ResultsThe groups showed similar language profiles, with a better understanding of words, followed by sentences, with the poorest comprehension for stories. Nouns were comprehended better than verbs; sentence constructions also showed a qualitatively similar picture, although some dissimilarities emerged. Verb comprehension was strongly related to sentence comprehension in both groups and related to story comprehension in the TD group only.ConclusionThe findings appear to support the view that receptive language skills follow the same developmental route in children with ID as seen in younger TD children, suggesting that language development is a robust process and does not seem to be differentially affected by ID even when delayed.
Duration and Voice Quality of Early Infant Vocalizations
Authors: Gregory Adele , Tabain Marija , Robb Michael 
Published: June 2018

Purpose
Infant vocal durations have been studied from a variety of perspectives, including medical, social, and linguistic. The resultant developmental profile across the first 6 months of life, however, is still far from clear. The purpose of this study was to evaluate the durational properties of infant vocalizations from the unique perspective of voice quality. By considering an infant's modal and nonmodal voice qualities, the developmental range of vocalizations produced by infants during the early months of life was captured.

Method
Four Australian English–speaking infants were recorded for approximately 1 hr per week during the first 6 months of life. A total of 6,309 vocalizations were perceptually identified and labeled according to voice quality. The duration of each vocalization was subsequently measured.

Results
A nonlinear curve was evident for the duration of all vocalizations combined. Duration increased significantly between Months 3 and 5. Modal voice was the only voice quality that displayed a linear increase in duration across the study. All other voice qualities displayed polynomial trends.

Conclusions
Based on the current results, the inconsistent pattern of vocal duration development found previously can be reconciled when voice quality properties of vocalizations are taken into account. A nonlinear curve is evident when a broad corpus of infant vocalizations is used, whereas a narrow corpus containing predominantly modal vocalizations displays a linear trend. The results demonstrate the necessity of including nonmodal voice qualities in infant duration experiments so as to not overstate the linear nature of duration increases.
Anatomy of the massive star-forming region S106
Authors: Schneider N. , Röllig M. , Simon R. , Wiesemeyer H. , Gusdorf A. , Stutzki J. , Güsten R. , Bontemps S. , Comerón F. , Csengeri T. , Adams J. D. , Richter H. 
Published: June 2018

The central area (40″ × 40″) of the bipolar nebula S106 was mapped in the [O I] line at 63.2 μm (4.74 THz) with high angular (6″) and spectral (0.24 MHz) resolution, using the GREAT heterodyne receiver on board SOFIA. The spatial and spectral emission distribution of [O I] is compared to emission in the CO 16 →15, [C II] 158 μm, and CO 11 →10 lines, mm-molecular lines, and continuum. The [O I] emission is composed of several velocity components in the range from –30 to 25 km s−1. The high-velocity blue- and red-shifted emission (v = −30 to –9 km s−1 and 8 to 25 km s−1) can be explained as arising from accelerated photodissociated gas associated with a dark lane close to the massive binary system S106 IR, and from shocks caused by the stellar wind and/or a disk–envelope interaction. At velocities from –9 to –4 km s−1 and from 0.5 to 8 km s−1 line wings are observed in most of the lines that we attribute to cooling in photodissociation regions (PDRs) created by the ionizing radiation impinging on the cavity walls. The velocity range from –4 to 0.5 km s−1 is dominated by emission from the clumpy molecular cloud, and the [O I], [C II], and high-J CO lines are excited in PDRs on clump surfaces that are illuminated by the central stars. Modelling the line emission in the different velocity ranges with the KOSMA-τ code constrains a radiation field χ of a few times 104 and densities n of a few times 104 cm−3. Considering self-absorption of the [O I] line results in higher densities (up to 106 cm−3) only for the gas component seen at high blue- and red velocities. We thus confirm the scenario found in other studies that the emission of these lines can be explained by a two-phase PDR, but attribute the high-density gas to the high-velocity component only. The dark lane has a mass of ~275 M⊙ and shows a velocity difference of ~1.4 km s−1 along its projected length of ~1 pc, determined from H13CO+ 1 →0 mapping. Its nature depends on the geometry and can be interpreted as a massive accretion flow (infall rate of ~2.5 × 10−4 M⊙ yr−1), or the remains of it, linked to S106 IR/FIR. The most likely explanation is that the binary system is at a stage of its evolution where gas accretion is counteracted by the stellar winds and radiation, leading to the very complex observed spatial and kinematic emission distribution of the various tracers.
Knowledge of endoscopic ultrasound-delivered fiducial composition and dimension necessary when planning proton beam radiotherapy
Authors: Gleeson Ferga , Tryggestad Erik , Remmes Nicholas , Beltran Chris , Kruse Jon , Haddock Michael , Hallemeier Christopher , Storm Andrew , Levy Michael 
Published: June 2018

Abstract
Background and study aims Little consideration has been given to selection of endoscopic ultrasound-guided fiducials for proton radiotherapy and the resulting perturbations in the therapy dose and pattern. Our aim was to assess the impact of perturbations caused by six fiducials of different composition and dimensions in a phantom gel model.
Materials and methods The phantom was submerged in a water bath and irradiated with a uniform 10 cm × 10 cm field of 119.7 MeV monoenergetic spot scanning protons delivered through a 45 mm range shifter. The proton “Bragg Peak” was evaluated.
Results Dose perturbations manifesting as dose reductions up to 30 % were observed. A carbon composite (1 × 5 mm) and gold (0.4 × 10 mm) fiducial with backload potential rather than dedicated EUS pre-loaded gold fiducial needles had the best performance in terms of minimizing the dose perturbation.
Conclusions Our data demonstrate that a carbon composite fiducial has a less untoward effect on proton therapy dose distribution than dedicated EUS pre-loaded gold fiducial needles. Such information is important to consider when selecting fiducials specifically for proton therapy.