bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypoxia-induced epigenetic silencing of polo-like kinase 2 promotes fibrosis in atrial fibrillation
Authors: Künzel Stephan Reinhard , Sekeres Karolina , Kämmerer Susanne , Kolanowski Tomasz , Meyer-Roxlau Stefanie , Piorkowski Christopher , Tugtekin Sems Malte , Rose-John Stefan , Yin Xiaoke , Mayr Manuel , Kuhlmann Jan Dominik , Wimberger Pauline , Grützmann Konrad , Herzog Natalie , Küpper Jan-Heiner , Guan Kaomei , Wagner Michael , Ravens Ursula , Weber Silvio , El-Armouche Ali 
Published: October 2018

AbstractFibrosis and inflammation promote atrial fibrillation (AF) and worsen its clinical outcome. The underlying molecular mechanisms, that are relevant for effective antifibrotic drug development, are still under debate. This study deciphers a novel mechanistic interplay between polo-like kinase 2 (PLK2) and the pro-inflammatory cytokine osteopontin (OPN) in the pathogenesis of atrial fibrosis. Compared to sinus rhythm (SR) controls, right atrial appendages and isolated right atrial fibroblasts from AF patients showed downregulation ofPLK2mRNA and protein levels, which were accompanied by remarkable hypoxia-sensitive DNA-methylation of thePLK2promotor. In an experimental setting, both, genetic deletion and pharmacological inhibition of PLK2 induced myofibroblast differentiation and reduced fibroblast proliferation. Notably, proteomics fromPLK2-deleted fibroblasts revealedde novosecretion of OPN. Accordingly, we observed higher OPN plasma levels in AF patients with atrial fibrosis compared to non-fibrosis AF patients. Hence, we provide evidence for PLK2 reactivation and/or OPN inhibition as potential novel targets to prevent fibrosis progression in AF.
High AOA short landing robust control for an aircraft
Authors: Tingting Yang , Aijun Li , Taimoor Muhammad , Amin Rooh ul 
Published: October 2018

Purpose
The purpose of this paper is to propose a high angle of attack short landing model for switched polytopic systems as well as to derive an equation for fluidic thrust vector deflection angle based on pressure to reduce the velocity during the landing phase of flight.

Design/methodology/approach
In this paper, robust control algorithm is proposed for a non-linear high angle of attack aircraft under the effects of non-linearities, tottering hysteresis, irregular and wing rock atmosphere. High angle of attack short landing flight under asynchronous switching is attained by using the robust controller method. Lyapunov function and the average dwell time scheme is used for obtaining the switched polytopic scheme. The asynchronous switching and loss of data are controlled asymptotically. The velocity of aircraft has been lucratively reduced during the landing phase of flight by using the robust controller technique.

Findings
The proposed algorithm based on robust controller including the effects of non-linearities guarantee the successful reduction of velocity for high angle of attack switched polytopic systems.

Practical implications
As the landing phase of an aircraft is one of the complicated stage, this algorithm plays a vital role in stable and short landing under the condition of high angle of attack (AOA).

Originality/value
In this paper, not only the velocity of flight has been reduced, but also the high angle of attack has been attained during the landing phase, because of which the duration of landing has been reduced as well, while in most of the previous research, it is based on low angle of attack and long landing duration.
A numerical study on the effects of design parameters on the acoustics noise of a high efficiency propeller
Authors: Ma Yunpeng , Guo Na 
Published: October 2018

PurposeA numerical study on the aerodynamic noise generation of a high efficiency propeller is carried out.Design/methodology/approachThree-dimensional numerical simulation based on Reynolds averaged N-S model is performed to obtain the aerodynamic performance of the propeller. Then, the result of the aerodynamic analysis is given as input of the acoustic calculation. The sound is calculated using the Farassat 1A which was derived from Ffowcs Williams–Hawkings equation and is compared with the measurements.FindingsMoreover, the fan is modified for noise reduction by changing its geometrical parameters such as span, chord length and torsion angle.Originality/valueThe variation trend of aerodynamic and acoustic are compared and discussed for different modification tasks. Some meaningful conclusions are drawn on the noise reduction of propeller.
Consumers’ behaviour in fast-food restaurants: a food value perspective from Spain
Authors: Izquierdo-Yusta Alicia , Gómez-Cantó Carmen M. , Pelegrin-Borondo Jorge , Martínez-Ruiz María Pilar 
Published: October 2018

Purpose
The purpose of this paper is to understand consumers’ behaviour in fast-food restaurants in Spain. To this end, the authors conducted a survey that combined a classification of food values, as proposed in the relevant literature, with a related model that links personal values to behaviour.

Design/methodology/approach
A sample of 400 consumers was gathered from two different, leading fast-food chains operating in Spain. With these data, respondents were grouped through hierarchical cluster analysis and K-measures, and in accordance with Lusk and Briggeman’s (2009) food values and the food-related lifestyle model. The authors validated these clusters by means of ANOVA and discriminant analysis, which led to useful observations about inter-group differences in consumers’ habits, as well as their satisfaction, trust and loyalty.

Findings
The results indicate that consumers can be clustered into three groups based their food values assessments: the “mainly utilitarian” group, the “mainly hedonic” group and the “ethical values” group. These groups not only demonstrate diverse habits, but also differ on key variables such as satisfaction, trust and loyalty.

Practical implications
The authors offer several managerial recommendations for designing and developing segmentation strategies in the fast-food industry. Any such strategies should acknowledge that all consumer groups appear to value restaurants’ efforts to provide them with both hedonic and utilitarian benefits, although the extent varies across groups.

Originality/value
Among the relevant literature, this research is the only one that examines the existence of distinct consumer groups based on their food values assessments. In addition, this paper analyses inter-group differences in terms of both diverse consumptions habits (frequency of visits, expenditure, etc.) and key marketing variables (satisfaction, trust and loyalty).
Are questionnaires a reliable method to measure food waste? A pilot study on Italian households
Authors: Giordano Claudia , Piras Simone , Boschini Matteo , Falasconi Luca 
Published: October 2018

Purpose
The purpose of this paper is to assess the reliability of questionnaires as a method of quantifying household food waste (FW), thus providing context regarding the validity of existing Italian estimates.

Design/methodology/approach
A total of 30 households were involved in a diary study that was conducted for one week. The participating households were first asked about their FW quantities in a questionnaire. Half of the households who filled their diaries properly were then audited through waste sorting analysis performed on their garbage. Non-parametric tests were used to test for differences in FW estimates between audited and non-audited households, as well as differences among estimates obtained through different quantification methodologies.

Findings
Edible FW was estimated to be 489 grams per week based on questionnaires, and 1,035 grams per week based on diaries. In the audited sub-sample of households, FW estimates were 334 grams per week based on questionnaires, 818 grams per week based on diaries and 1,058 grams per week based on waste sorting analysis.

Research limitations/implications
Given the small sample size in the present study, future studies can utilize larger samples to assess whether the differences identified in estimates can be replicated. Future studies can also inquire into the behavioral biases that led consumers to underestimate their FW.

Practical implications
Results of the present study point against the use of questionnaires to quantify household FW, hence raising some doubt on the reliability of existent Italian estimates. Where waste sorting is unfeasible, the use of adjustment methods or diaries is suggested to better inform policies.

Originality/value
This study is one of the first on FW quantification that tests three different methodologies on the same sample, and is the first to do so in Italy, where estimates are still very poor.
Effects of menu labelling on students′ food choice: a preliminary study
Authors: Krešić Greta , Liović Nikolina , Pleadin Jelka 
Published: October 2018

PurposeThe purpose of this paper is to assess the relationship between nutrition knowledge and grocery store nutrition label use, with using nutrition information disclosure on menu selection in a group of hospitality management students, who shall be responsible for menu labelling in their future careers.Design/methodology/approachA between-subject design included 324 students, who were randomly assigned to choose from a menu labelled as follows: unlabelled; kcal label only; graphical label providing information on the per cent of the recommended daily intake of energy and four nutrients. Their nutrition knowledge and habit of reading grocery store nutrition labels were tested using an additional questionnaire.FindingsThe results showed that the provision of energy value information resulted in the selection of less energetic, less fat and less salted food, while a graphical label additionally led to the selection of food having a lower saturated fatty acid (SFA) and sugar content. Multiple regression analysis showed that the habit of packaged food nutrition label reading was a significant predictor of choosing food having a lower energy (p<0.001), fat (p<0.001), SFA (p<0.001), sugar (p<0.001) and salt (p=0.003) content, while the influence of nutrition knowledge on food selection was proven insignificant.Originality/valueGiven the established positive impact of menu labelling, these findings support the future European policy mandating energy and nutrient content disclosure on menus, but also point to the need for more-intense consumer education.
Evaluating indicators of the agility of the green supply chain
Authors: Sayyadi Tooranloo Hossein , Alavi Masoume , Saghafi Sepideh 
Published: October 2018

PurposeNowadays, the main problem of industries is the issue of environmental pollution. The green supply chain (GSC) is one of the processes that can be effective to consider this issue and its practices in all working processes in every organizations, so that the concept of GSC has been emerged with the acceleration of the government regulations and rules to achieve environmental standards and the increasing demands of consumers to supply green products. Therefore, the organizations should move toward the development of environmental activities in today’s turbulent world. In other words, the current organizations should consider making their supply chain more agile and green to survive in the competition arena or in other words, they should consider making agile the GSC. The necessity of considering this issue needs to identify the evaluating indicators of the agility of the GSC. This study aims to consider this issue.Design/methodology/approachWith reviewing the research literature and having survey with the experts, totally 7 criteria and 37 sub-criteria were identified as the evaluating indicators of the agility of the GSC. The results from collecting research data and using the confirmatory-factor analysis suggest the suitability of the above-mentioned indicators.FindingsThe idea of the GSC is to remove or minimize the greenhouse, chemical/hazardous gases and waste throughout the supply chain. On one hand, the agility of the supply chain as an operational capability in quick response to the uncertain and turbulent markers not only improves the performance of the company but also leads to cost decrease and increase of the professional capabilities. Therefore, the organizations should step toward the development of the environmental activities in the today’s turbulent world. The importance of the issue of agility and considering the environment in the supply chain double the necessity of identification of the factors of agility of the GSC.Originality/valueThe present research considers the identification of the evaluating indicators of the agility of the GSC in industries.
This place is like the jungle: discussions about psychoactive substances on a cryptomarket
Authors: Rolando Sara , Beccaria Franca 
Published: October 2018

Purpose
The purpose of this paper is to analyse dynamics amongst members to better understand in what terms and to what extent marketplace forums can be seen as new forms of harm reduction.

Design/methodology/approach
This is a qualitative analysis focused on conversations about psychoactive substances on the forum community of AlphaBay Market. A sample consists of 100 online threads. The data, collected in July 2016, were analysed by applying the grounded theory approach with the support of Atlas.ti.

Findings
Conversations in the marketplace forum focus mostly on the purchase. Concerns and disputes are voiced in a significant proportion of them, and interactions are affected by a climate of distrust where stigmatisation processes can emerge between users of different drug categories. This casts a certain amount of doubt on the thesis that marketplace forums – like online forums – are new forms of harm reduction and peer-led communities.

Research limitations/implications
The study focuses on only one marketplace forum. Other such forums should be analysed to corroborate its findings.

Practical implications
Harm reduction interventions in the online environment should take different form according to the forum type, and take the differences and boundaries that separate users of different substances into account.

Originality/value
Thanks to its infrequently used qualitative approach, the study provides a more thorough understanding of the relationships on marketplace forums.
Paradox and legitimacy in construction: how CSR reports restrict CSR practice
Authors: Watts Greg , Fernie Scott , Dainty Andy 
Published: October 2018

PurposeCorporate social responsibility (CSR) is a prominent topic of debate, and yet remains subject to multiple interpretations. Despite this ambiguity, organisations need to communicate their CSR activity effectively in order to meet varied stakeholder demands, increase financial performance and in order to achieve legitimacy in the eyes of clients and various stakeholders. The purpose of this paper is to explore how CSR is communicated, and the impact such communication methods have on CSR practice. More specifically, it examines the disconnect between the rhetoric espoused in CSR reports and the actualities of the ways in which CSR is practiced.Design/methodology/approachA qualitative content analysis of 100 CSR reports published by nine construction contractors informed the design of qualitative interviews. In total, 17 interviews were then conducted with contractors and public body clients.FindingsStrategic ambiguity explains how contractors circumvent the problem of attending to conflicting stakeholder CSR needs. However, this results in a paradox where CSR is simultaneously sustained as a corporate metric and driver, whilst being simultaneously undermined in being seen as a rhetorical device. By examining this phenomenon through the lens of legitimacy, the study reveals how both the paradox and subsequent actions of clients that this provokes, act to restrict the development of CSR practice.Originality/valueThis is the first study to use the lens of legitimacy theory to analyse the relationship between CSR reporting and CSR practice in the construction industry. In revealing the CSR paradox and its ramifications the research provides a novel explanation of the lack of common understandings and manifestations of CSR within the construction sector.
Role of shopping quality, hedonic/utilitarian shopping experiences, trust, satisfaction and perceived barriers in triggering customer post-purchase intentions at airports
Authors: Han Heesup , Lee Myong Jae , Kim Wansoo 
Published: October 2018

Purpose
This paper aims to extend the knowledge of travelers’ shopping behaviors at airport duty-free stores by investigating the role of multiple quality factors, value dimensions, trust and satisfaction. Moreover, the influence of possible barriers to airport shopping is examined.

Design/methodology/approach
Quantitative data collection including a survey was used. A structural equation modeling was used for data analysis.

Findings
The results showed that the proposed conceptual framework provided sufficiently explained travelers’ post-purchase intentions for airport duty-free shopping. Hedonic value and trust in airport duty-free shopping were of greatest importance in determining intentions. The quality of products and physical environment also showed relative importance among cognitive drivers. The findings from the metric invariance test indicated the significant moderating impact of travelers’ perceived barriers to airport shopping. The mediating impact of study variables was also identified.

Practical implications
Findings help airport practitioners improve their knowledge of travelers’ shopping behaviors at airport duty-free stores and help them to develop efficient methods to facilitate air travelers’ commercial activities at an airport.

Originality/value
Non-aeronautical business is emerging as a means of revenue maximization in the airport industry, yet there is a lack of understanding about air travelers’ commercial activities at airports. This study filled this void through the development of sturdy framework for air travelers’ non-aeronautical commercial activities at an airport.
Efficiency improvements in the PV plants market: an application to the Spanish case
Authors: Arcos-Vargas Angel , Nuñez Fernando , Vivas Juan José 
Published: October 2018

Purpose
Spain has one of the greatest photovoltaic potentials in Europe. The boom suffered in the photovoltaic sector during the years 2007 and 2008 led to instability in the electrical system, prompting the legislator to develop a large number of legislative changes trying to control the electric system tariff deficit. These measures profoundly affected plant owners creating a non-transparent secondary market, which are not covered by the current exchange platforms. The purpose of this paper is to analyze the current situation of the photovoltaic market in Spain, try to understand it based on its historical sequence and propose efficiency improvement measures, based on the implementation of best practices and market mechanisms.

Design/methodology/approach
This paper studies the legislative evolution in the photovoltaic sector in Spain and its effect on owners and investors. The authors propose an intermediation system that improves the efficiency of the secondary market.

Findings
The authors propose an intermediation system that improves the efficiency of the secondary market.

Originality/value
The authors have not found any other paper that proposes the creation of a market for photovoltaic facilities to increase efficiency.
Moving later in life – preferences and opportunity
Authors: Kulander Maria 
Published: October 2018

Purpose
Statistics from Eurostat show that several European countries have an increasing proportion of elderly people, making their housing situation of increasing interest. For many years, it has been policy in Sweden to help elderly people remain in their current homes for as long as possible. This paper aims to find reasons why people want to move at different stages in life and investigate whether the pattern follows the life cycle in housing. Earlier research has been performed in the USA (Gibler and Clements III, 2011) and in China (Jia and Heath, 2016), but these questions remain understudied in Sweden.

Design/methodology/approach
A model of the demand for adapted houses is designed and tested on data gathered in Gävle in 2012. The method uses a binary choice model with stated preference data.

Findings
The results of this study show that earlier preferences and age determine the future living situation, but that senior living (rental or condominium) is most popular as a future home.

Practical implications
Not everyone has the economic resources to move according to their preferences; reasons include high monthly costs and taxes. Changes in the tax system may produce better moving chains and increase the supply of affordable housing.

Originality/value
The model in this paper could guide future studies within the area.
Analysing ar-rahnu in the context of informal credit market theory
Authors: Nik Azman Nik Hadiyan , Kassim Salina , Adeyemi Adewalee Abideen 
Published: October 2018

Purpose
This study aims to offer a new area of discourse by investigating the factors determining the usage of the Islamic non-bank financing product ar-rahnu (Islamic pawnbroking) among women micro-entrepreneurs in Malaysia within the framework of the informal credit market theory.

Design/methodology/approach
The study is based on primary data obtained by using self-administered questionnaires distributed in three states in Malaysia: Kedah, Kelantan and Terengganu. The questionnaires were distributed to a total of 750 participants, with each state contributing 250 respondents. Total number of respondents valid for data analysis was however 600.

Findings
Based on descriptive and inferential statistics by using the IBM statistical package for the social sciences and structural equation modelling analysis of moment structures, the results show that the main factor influencing women micro-entrepreneurs to use ar-rahnu is the service charge.

Research limitations/implications
This study only covers three states in Malaysia and is limited to examining the use of ar-rahnu by women micro-entrepreneurs in those states.

Practical implications
As micro-entrepreneur s often face constraints to obtaining financial access in the formal credit market, ar-rahnu provides an alternative mode of obtaining business financing to female micro-entrepreneurs, so they can sustain their operations and even expand their businesses. The significance of such factors like service fee, as revealed in this study, indicates that managers should focus on this element when offering Islamic financial products, especially to women micro-entrepreneurs.

Originality/value
The informal credit market theory is frequently used in conventional studies. This paper adds Sharīʿah compliance in the context of this theory as a new area to be considered when discussing Islamic financial products.