bluuebunny/crossref_metadata_2025_split huggingface dataset:
Never too old for an inherited condition
Authors: Robinson Philip 
Published: October 2018

AbstractPrimary ciliary dyskinesia is an uncommon, inherited condition causing progressive suppurative airway lung disease with subsequent bronchiectasis, chronic rhinitis‐sinusitis, deafness and reduced fertility. Diagnosis is often delayed by lack of awareness of the condition in the medical community and limited access to the few centres in Australia able to do full diagnostic testing. This report details the late diagnosis of primary ciliary dyskinesia in two adults who have had long‐standing interactions with medical services but in whom the diagnosis was never considered or even dismissed. Greater awareness of the condition will reduce time to diagnosis, prevent administration of ineffective therapy and allow earlier institution of targeted therapy.
Low rates of eligibility for lung cancer screening in patients undergoing computed tomography coronary angiography
Authors: Lyne Christopher , Zaw Shane , King Bridget , See Katharine , Manners David , Al‐Kaisey Ahmed , Joshi Subodh , Farouque Omar , Irving Louis , Johnson Douglas , Steinfort Daniel 
Published: October 2018

AbstractIncidental findings, including pulmonary nodules, on computed tomography coronary angiography (CTCA) are common. Previous authors have suggested CTCA could allow opportunistic screening for lung cancer, though the lung cancer risk profile of this patient group has not previously been established. Smoking histories of 229 patients undergoing CTCA at two tertiary hospitals were reviewed and only 25% were current or former smokers aged 55–80 years old. Less than half of this group were eligible for screening based on the PLCOm2012 risk model. We conclude that routine screening in the form of full thoracic field imaging, of individuals undergoing CTCA is not appropriate as it would likely result in net harm.
Three‐dimensional (3D) flexible nanofibrous network knitting on hierarchical porous architecture
Authors: Ren Bo , Liu Jingjing , Huo Wenlong , Gan Ke , Yan Shu , Chen Yugu , Lu Yuju , Yang Jinlong , Huang Yong 
Published: October 2018

AbstractHierarchical structured porous ceramics have attracted tremendous research interests because of their numerous excellent properties including robust mechanical strength and large surface area. In this work, silicon carbide (SiC)‐based porous ceramics with three levels of pore hierarchy are fabricated from silicon particle‐stabilized foams and a subsequent one‐step calcination after they were embedded with coke. Three‐dimensional (3D) flexible nanofibrous network is adhered and wrapped on cell walls of porous ceramics, which is readily fine‐tuned and tailored by the temperature to provide optimized pore structure. The resultant SiC‐based porous ceramics present a density of 1.03 g/cm3 at a porosity of 72% with a large quantity of hierarchical micro‐ and macropores. This hierarchical structure leads to robust compressive strength (23.52 MPa) and large surface area (64.32 m2/g). The fabrication method is straightforward and sought‐after, providing a facile technical route for advanced hierarchical porous ceramics used in filtration and catalysis fields.
Transparent red ‐emitting silicone resin for color conversion and encapsulation of NUV light‐emitting diodes
Authors: Chen Hong , Wang Yao , Lin Jianhui , Shuai Minmin , Zhu Haidi , Zhang Wengong , Ling Qidan 
Published: October 2018

AbstractHerein, a novel transparent phenyl vinyl silicone resin nanocomposite containing exfoliated fluorescent Eu‐containing hydrotalcite‐like compound (EFHSN) is developed to serve as a dual role of color conversion and encapsulation material. Excited by near‐NUV light, the EFHSN emits a strong characteristic red light (614 nm). Meanwhile, the EFHSN shows not only excellent transparency (T > 95%) in the UV‐Vis region and high refractive index (1.46) but also superior thermal stability, which could meet the need of commercial encapsulation materials and optical application. Therefore, the EFHSN is expected to be used in InGaN‐based NUV light‐emitting diodes and flexible optoelectronic device.
Enhancing validity through cognitive interviewing. A methodological example using the Epilepsy Monitoring Unit Comfort Questionnaire
Authors: Egger‐Rainer Andrea 
Published: October 2018

AbstractAimsTo identify problematic items, assess completeness and user‐friendliness, and undertake modifications to enhance face validity of the newly developed Epilepsy Monitoring Unit Comfort Questionnaire.DesignQualitative‐descriptive cross‐sectional study.MethodsFive iterative rounds of cognitive interviewing were conducted with members of the target population between July ‐ November 2017. Think‐aloud technique, verbal probing, and observation were used, to assess how respondents understood and answered questions. Data analysis was based on the framework method; an eight‐column framework matrix was created for this purpose.ResultsIn 25 interviews, problems regarding completeness of the item pool, comprehension of items, retrieval of information, judgment while finding answers and reporting the appropriate responses could be detected. According to the results, 27 items remained unchanged, 11 items were reworded, and six items were added. Instructions section of the questionnaire was reworked, too.ConclusionAlthough time‐consuming, cognitive interviewing turned out to be a valuable approach for revealing problems in an instrument, which would, otherwise, remain undetected and threaten validity.
Bibliometric analysis of six nursing journals from the Web of Science, 2012–2017
Authors: Giménez‐Espert María del Carmen , Prado‐Gascó Vicente Javier 
Published: October 2018

AbstractAimThe purpose of this study was to perform a bibliometric analysis of the six most important nursing journals according to the impact factor of the Science Citation Index through Web of Science®. The following journals were included: International Journal of Nursing Studies, Nurse Education Today, Journal of Nursing Scholarship, Nursing Outlook, Worldviews on Evidence‐Based Nursing and the Journal of Advanced Nursing.BackgroundIn the nursing field, bibliometric analysis and maps have been used to analyse the production of some journals but not for the comparison of different journals.Design/MethodUsing descriptive bibliometrics, we studied scientific production of different journals and bibliometric maps were used to visualize the content of published articles.ResultsThe six journals included showed that 3,937 articles were written by 1,1371 authors from 2,980 institutions and 84 countries from 2012 – 2017. Journal of Advanced Nursing had a greater number of publications and citations. The most prolific authors showed a tendency to publish first in Journal of Advanced Nursing and then in International Journal of Nursing Studies and Nurse Education Today. The frequency of citation was higher in International Journal of Nursing Studies followed by Journal of Advanced Nursing. The most collaborative authors and those with the most co‐citations published more than half of their publications in Journal of Advanced Nursing. The topics most commonly researched by these authors were job satisfaction, collaborative practices, and nurse leaders.ConclusionThis bibliometric analysis contributes to the understanding of the current state of nursing research and its evolution.
The effectiveness of peer support on self‐efficacy and quality of life in adults with type 2 diabetes: A systematic review and meta‐analysis
Authors: Kong Ling‐Na , Hu Ping , Yang Li , Cui Dan 
Published: October 2018

AbstractBackgroundPeer support has been suggested as a promising approach for diabetes management. No conclusive evidence exists on the effects of peer support on self‐efficacy and quality of life in adults with type 2 diabetes.ObjectiveTo assess the effectiveness of peer support on self‐efficacy and the quality of life in adults with type 2 diabetes.DesignA systematic review and meta‐analysis of randomized controlled studies.Data sourcesWe searched PubMed, Embase, Cochrane Central Register of Controlled Trials and Allied Health Literature database guide for relevant literatures from inception to 30 September 2017.Review methodsThe review was conducted according to the guidelines of Cochrane Collaboration. The outcomes were self‐efficacy and quality of life. The standardized mean difference and 95% confidence intervals were calculated for pooled results.ResultsA total of 15 studies met the inclusion criteria. The pooled results revealed that peer support did not significantly improve self‐efficacy and quality of life in adults with type 2 diabetes, but significantly improved self‐efficacy and quality of life in studies with intervention duration ≤6 months. There was no evidence of publication bias.ConclusionPeer support intervention did not lead to better effects on the improvement in self‐efficacy and quality of life among adults with type 2 diabetes. However, peer support with intervention duration not more than 6 months had positive effects on self‐efficacy and quality of life. More high‐quality studies with large sample size are needed to support or counter the results.
Music intervention for pain and anxiety management of the primiparous women during labour: A systematic review and meta‐analysis
Authors: Chuang Ching‐Hui , Chen Po‐Cheng , Lee ChihChen Sophia , Chen Chung‐Hey , Tu Yu‐Kang , Wu Shih‐Chung 
Published: October 2018

AbstractAimsTo determine the effect of music on the management of pain and anxiety in primiparous women during labour.BackgroundMusic is cost‐effective intervention in clinical practice to reduce pain, stress, and anxiety. However, a systematic review with meta‐analysis for investigating its effects during labour is still lacking.DesignA systematic review with meta‐analysis.Data sourcesMEDLINE, EMBASE, and CINAHL databases.Review methodsRandomized controlled trials or quasi‐experimental trials concerning the effects of music among primiparous women who were expected to give normal spontaneous delivery were searched and screened up to 31 July 2017. The recruited trials for this review were compliant with the standards of the Cochrane Handbook for Systematic Reviews of Interventions.ResultsA total of 392 primiparous pregnant women (197 in the music intervention group and 195 in the routine care group) from five studies were included in this review. Music as an intervention seemed to lower the pain scores for primiparous women during labour, but the effect was not statistically significant. However, there was a significant benefit of music intervention compared with routine care for primiparous women during labour. In the sensitivity analysis, music intervention showed significant effect on the improvement of pain and anxiety for primiparous women during labour.ConclusionMusic intervention may be an effective intervention for the management of pain and anxiety for primiparous women during labour.
Mexican‐American adolescents’ perceptions about causes of perinatal depression, self‐help strategies, and how to obtain mental health information
Authors: Recto Pamela , Dimmitt Champion Jane 
Published: October 2018

AbstractProblemPerinatal depression is a public health concern as it is associated with adverse pregnancy outcomes. Previous studies have recommended further examination of perinatal depression among Mexican‐American adolescents. Thus, the purpose of this study was to understand pregnant and postpartum Mexican‐American adolescents’ knowledge and beliefs concerning perinatal depression.MethodsThis qualitative descriptive study examined perceptions about the causes of perinatal depression, self‐help strategies, and how to obtain mental health information. Data were analyzed using deductive and inductive qualitative content analysis. A convenience sample, consisiting of 20 pregnant and postpartum adolescents, self‐identified as Mexican‐Americans, between the ages of 15 and 19 years was interviewed.FindingsThe quality of relationships with their family and significant other and difficulties in transitioning to motherhood were described as potential causes for depression. Journaling, exercising, and spending time with friends and family were identified as self‐help strategies. Healthcare providers, the internet, and mothers who have experienced depression were stated as helpful sources of mental health information.ConclusionAn assessment of their psychosocial environment is indicated to identify risk or protective factors for perinatal depression. Its consideration and inclusion in interventions may optimize mental health among perinatal adolescents.
Postablation cerebral embolisms in balloon‐based atrial fibrillation ablation with periprocedural direct oral anticoagulants: A comparison between cryoballoon and HotBalloon ablation
Authors: Nakamura Kohki , Sasaki Takehito , Take Yutaka , Okazaki Yoshinori , Inoue Mitsuho , Motoda Hiroyuki , Miki Yuko , Niijima Katsura , Yamashita Eiji , Koyama Keiko , Funabashi Nobusada , Naito Shigeto 
Published: October 2018

AbstractIntroductionThis prospective observational study aimed to investigate the incidence of symptomatic and silent cerebral embolisms after balloon‐based ablation of atrial fibrillation (AF) in patients receiving periprocedural anticoagulation with direct oral anticoagulants (DOACs), and compare that between cryoballoon and HotBalloon ablation (CBA and HBA).Methods and ResultsWe enrolled 123 consecutive AF patients who underwent a balloon‐based pulmonary vein isolation (PVI) and brain magnetic resonance (MR) imaging after the ablation procedure (CBA, n = 65; HBA,
n = 58). The DOACs were continued in 62 patients throughout the periprocedural period and discontinued in 61 on the procedural day. Intravenous heparin was infused to maintain an activated clotting time of 300 to 400 seconds during the procedure. No symptomatic embolisms occurred in this series. Silent cerebral ischemic lesions (SCILs) were observed on MR imaging in 22 patients (17.9%), and the incidence of SCILs did not significantly differ between the CBA and HBA groups (21.5 vs 13.8%;
P = 0.263). According to a multivariate logistic regression analysis, an older age was an independent positive predictor of SCILs (odds ratio, 1.062; 95% CI, 1.001‐1.126;
P = 0.046), but neither the balloon catheter type nor periprocedural continuation or discontinuation of the DOACs were significant predictors. The incidence of major and minor bleeding complications was comparable between the CBA and HBA groups (1.5 vs 0%,
P = 0.528; 7.7 vs 5.2%,
P = 0.424).ConclusionsBoth CBA and HBA of AF revealed a similar incidence of postablation cerebral embolisms. Elderly patients may be at a risk of SCILs after a balloon‐based PVI with periprocedural DOAC treatment.
Targeted ablation of specific electrogram patterns in low‐voltage areas after pulmonary vein antral isolation in persistent atrial fibrillation: Termination to an organized rhythm reduces atrial fibrillation recurrence
Authors: Efremidis Michael , Vlachos Konstantinos , Letsas Konstantinos P. , Bazoukis George , Martin Ruairidh , Frontera Antonio , Asvestas Dimitrios , Saplaouras Athanasios , Kitamura Τakeshi , Georgopoulos Stamatios , Valkanas Kosmas , Karamichalakis Nikolaos , Takigawa Masateru , Sideris Antonios , Derval Nicolas , Sacher Frederic , Jais Pierre 
Published: October 2018

AbstractBackgroundAblation strategies have been developed to improve outcomes in patients with persistent atrial fibrillation (PsAF). However, the impact of atrial fibrillation (AF) termination on late AF recurrence is not well known. The aim of our study was to evaluate the impact of AF termination to atrial tachycardia (AT) or sinus rhythm (SR) during catheter ablation on late AF recurrence after the 3‐month blanking period.Methods and ResultsWe prospectively recruited 140 patients (mean age: 58.5 ± 12.3 years old, 74.3% males) with uninterrupted PsAF of a mean duration of 3.7 months. Pulmonary vein antral isolation (PVAI) was the first ablation step, and if AF did not terminate (to SR or AT), we ablated low‐voltage areas less than 0.4 mV with specific electrogram characteristics. We successfully converted AF to AT or SR in 56 patients (40%) during PVAI (n = 24) or low‐voltage ablation (
n = 32). The remaining 84 patients (60%) were electrically cardioverted to SR at the end of the procedure. One hundred patients (71.4%) maintained SR after a single procedure during a mean follow‐up of 21.1 ± 0.8 months. Of the 56 patients with AF termination, 46 (82.1%) had no recurrence, while in the group of 84 patients without AF termination, 54 patients (64.3%) remained in SR (
P < 0.02).ConclusionAblation of PVAI and specific electrograms in low‐voltage areas less than 0.4 mV can lead to encouraging outcomes with a low recurrence rate as well as a lower need for redo procedures.
Interesting case of dual tachycardia in a patient with surgical closure of atrial septal defect
Authors: Mohanan Nair Krishna Kumar , Namboodiri Narayanan , Kevadiya Hiren , Valaparambil Ajitkumar 
Published: October 2018

AbstractA 34‐year‐old gentleman, who had undergone pericardial patch closure of ostium secundum atrial septal defect (ASD) at 8 years of age, was evaluated for shortness of breath. Electrocardiogram revealed typical atrial flutter with varying atrioventricular conduction. Echocardiogram showed no residual ASD or pulmonary hypertension and good biventricular function. He was taken for an electrophysiological study with the intention of radiofrequency ablation of the typical flutter.
The antidepressant drug, sertraline, hinders bone healing and osseointegration in rats’ tibiae
Authors: Abu Nada Lina , Al Subaie Ahmed , Mansour Alaa , Wu Xixi , Abdallah Mohamed‐Nur , Al‐Waeli Haider , Ersheidat Ala’ , Stone Laura S. , Murshed Monzur , Tamimi Faleh 
Published: October 2018

AbstractAimSelective serotonin reuptake inhibitors (SSRIs) are one of the most common antidepressant drugs. SSRI use is associated with increased risk of bone fracture and titanium implant failure. The aim of this in vivo study was to investigate the effect of SSRIs on osseointegration and bone healing.Materials and MethodsOn a total of 24 Sprague‐Dawley rats, a custom‐made titanium implant was placed in the left tibia, while a unicortical defect was created in the right tibia. Rats were assigned randomly into two groups and received a daily dose of either sertraline (5 mg/kg) or saline. After two weeks, they were euthanized and bone healing and osseointegration were assessed by micro‐CT and histology.ResultsBone formation in bone defects was significantly lower (p < 0.05) in sertraline‐treated rats (BV/TV = 20.67 ± 11.98%) compared to the controls (BV/TV = 37.87 ± 9.56%). Furthermore, the percentage of osseointegration was significantly lower (p < 0.05) in sertraline‐treated rats (34.40 ± 7.17%) compared to the controls (54.37 ± 8.58%).ConclusionSertraline hinders bone healing and implant osseointegration.
Association between periodontitis and risk of Alzheimer′s disease, mild cognitive impairment and subjective cognitive decline: A case–control study
Authors: Holmer Jacob , Eriksdotter Maria , Schultzberg Marianne , Pussinen Pirkko J. , Buhlin Kåre 
Published: October 2018

AbstractAimsTo test the hypothesis that periodontal disease contributes to increased risk of mild cognitive impairment (MCI), subjective cognitive decline (SCD) and Alzheimer′s disease (AD).Materials and methodsThis case–control study was conducted over a 3‐year period in the municipality of Huddinge, Sweden. In total, 154 cases were consecutively enrolled from the Karolinska Memory Clinic at the Karolinska University Hospital and allotted to three diagnostic groups: AD, MCI and SCD, collectively referred to as “cases.” Seventy‐six cognitively healthy age‐ and gender‐matched controls were randomly sampled through the Swedish population register. All cases and controls underwent clinical and radiographic oral examinations. Statistical analysis was based on logistic regression models adjusted for potential confounders.ResultsPoor oral health and marginal alveolar bone loss were more prevalent among cases than among controls. The cases group was associated with generalized marginal alveolar bone loss (odds ratio [OR] = 5.81; 95% confidence interval [CI] = 1.14–29.68), increased number of deep periodontal pockets (OR = 8.43; CI 4.00–17.76) and dental caries (OR = 3.36; CI 1.20–9.43).ConclusionThe results suggest that marginal periodontitis is associated with early cognitive impairment and AD. However, the study design does not preclude noncausal explanations.
Prevalence and risk indicators of peri‐implant diseases in Spain
Authors: Rodrigo Daniel , Sanz‐Sánchez Ignacio , Figuero Elena , Llodrá Juan Carlos , Bravo Manuel , Caffesse Raul G. , Vallcorba Nuria , Guerrero Adrián , Herrera David 
Published: October 2018

AbstractAimTo evaluate the prevalence of peri‐implant diseases in Spain, as well as the associated risk indicators.Material and MethodsThis is a cross‐sectional study using a network of sentinel dentists, who randomly selected 10 patients with implants (placed, at least, 5 years before), which were clinically and radiographically evaluated. Case definitions were established for peri‐implant mucositis [bleeding on probing (BOP) and no bone level ≥2 mm] and peri‐implantitis (BOP plus bone level ≥2 mm). Potential predictor variables, at univariate and multivariate levels, were explored by means of binary logistic regression.ResultsA total of 49 sentinel dentists provided complete data from 474 implants in 275 patients. At implant level, prevalences for peri‐implant mucositis and peri‐implantitis were 27% (95% confidence interval [CI] 22–32) and 20% (95% CI: 15–24), respectively, with 17% of implants (14–21) with bone level ≥2 mm without BOP. At patient level, prevalences were 27% (22–32), 24% (19–29) and 18% (13–22), respectively. In the multiple regression analysis, statistically significant associations for peri‐implantitis (p < 0.10) were found for gender, peri‐implant supportive therapy, implant location, diameter and surface, type of prosthesis and access to interproximal hygiene.ConclusionsIn this representative subject sample across Spain, the prevalence of peri‐implant diseases was high (51%).
A 5‐year prospective study on the clinical and aesthetic outcomes of alveolar ridge preservation and connective tissue graft at the buccal aspect of single implants
Authors: Eghbali Aryan , Seyssens Lorenz , De Bruyckere Thomas , Younes Faris , Cleymaet Roberto , Cosyn Jan 
Published: October 2018

AbstractAimTo evaluate the 5‐year aesthetic outcome of single implants following alveolar ridge preservation (ARP) and connective tissue graft (CTG) at the buccal aspect.Materials and MethodsThirty‐seven periodontally healthy non‐smoking patients received flapless tooth extraction, ARP with a deproteinized bovine bone mineral with 10% collagen (DBBMC), implant placement (4–6 months later), a provisional screw‐retained crown and CTG at the buccal mucosa (3 months later) and a permanent crown (3 months later). The aesthetic results were the primary outcome and the clinical results the secondary outcome of the study. Both outcomes were compared to those after 1 year. Mucosal thickness (MT) was registered using a non‐invasive ultrasonic device.ResultsThirty‐two patients attended the 5‐year re‐assessment, and all implants survived. Mean marginal bone loss was 0.53 mm at 1 year and 0.47 mm at 5 years (p = 0.439). Mesial Papilla showed a further re‐growth between 1 and 5 years (p = 0.043). Mid‐facial recession amounted to 0.05 mm and 0.12 mm at 1 and 5 years, respectively (p = 0.161). The Pink Esthetic Score was 11.00 and 11.17 at 1 and 5 years, respectively (p = 0.596). MT gain amounted to 0.97 mm (relative stability: 90.5%) and 0.91 mm (relative stability: 85%) at 1 and 5 years, respectively (p = 0.249).ConclusionARP and CTG resulted in favourable clinical and aesthetic outcomes. CTG substantially increased MT with acceptable stability over a 5‐year period.