bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic Outcomes in AIDS-Associated Kaposi's Sarcoma Patients on Antiretroviral Therapy Treated with Chemotherapy at Two Tertiary Hospitals in Lusaka, Zambia
Authors: Mtonga Watson , Mujajati Aaron , Munkombwe Derick , Kalungia Aubrey , Muungo Lungwani Tyson , West John , Wood Charles , Ngalamika Owen 
Published: July 2018

The incidence of HIV-associated Kaposi’s sarcoma (KS) remains high in Zambia in the antiretroviral therapy era. The most efficacious treatment regimen for KS has yet to be established. In both developed and developing countries, treatment regimens have had limited efficacy. Late presentation in Africa affects therapeutic outcomes.Objective:The aim of this study was to determine therapeutic outcomes of epidemic KS patients on combination antiretroviral therapy (cART) after completion of six cycles of Adriamycin, Bleomycin, and Vincristine (ABV) chemotherapy.Methods:This was a descriptive cross-sectional study. Study participants were drawn from a study database of confirmed incident KS patients seen at the Skin Clinic of the University Teaching Hospitals (UTH) during the period between August, 2015 and September, 2016.Results:Of the 38 successfully recruited study participants, a complete response was documented in 18 (47%) after 6 cycles of ABV whereas 20 (53%) experienced a partial response. KS recurrence was observed in 8 (44%) of the individuals that experienced an initial complete response. At the time of the study, clinical assessment revealed that KS lesions had completely regressed in 21 (55%) of all the patients.Conclusion:ABV chemotherapy appears ineffective in long-term resolution of epidemic KS patients on ART. Recurrence rates are high after chemotherapy in patients that experience initially favorable responses to treatment. There is a need to diagnose KS earlier, and to develop more efficacious treatment options in order to reduce recurrence rates for epidemic KS.
Micropollutants in wastewater and their degradation by ferrates (VI)
Authors: Kubiňáková Emília , Fašková Lucia , Králiková Eva , Híveša Ján , Mackuľak Tomáš 
Published: July 2018

Abstract
In recent years, the occurrence of micropollutants (MPs) in sewage-, surface-, ground- and drinking water, and their removal processes are widely discussed. The content of various chemical organic/inorganic pollutants (pharmaceuticals, drugs, pesticides, hormones, heavy metals etc.) has increased over the years. Most of these compounds are not eliminated or biotransformed in traditional wastewater treatment plants. Several advanced oxidation processes (AOPs) for the removal of resistant micropollutants from water sources have been studied. Ferrate (VI) has aroused interest as an alternative oxidizing agent in drinking water preoxidation treatment. Electrochemically prepared potassium ferrate was used to remove the studied organic micropollutants. The effect of ferrate on two widely occurring organic micropollutants in water sources, carbamazepine and caffeine, was investigated. High performance liquid chromatography (HPLC) was used for sample analysis.
Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience
Authors: Hasković Edhem , Bureković Azra , Husić Adnan , Fočak Muhamed , Islamagić Erna 
Published: July 2018

Abstract
The aim of this study was to analyze the values of biochemical parameters in patients with diabetic ketoacidosis and ketonuria. In this prospective comparative study conducted at the Clinical Center of the University of Sarajevo, hundred patients of both genders with diabetes mellitus were enrolled. Newly diagnosed diabetic patients with complications like acute ketoacidosis (n = 50) and ketonuria (n = 50) were included in this study and compared. The values of biochemical parameters in these patients were analyzed. We found that mean values of pH, base excess, hydrogencarbonate, sodium, glucose, urea and creatinine concentrations in patients with ketoacidosis were significantly different compared to patients with ketonuria. The values of potassium and calcium serum concentrations were not significantly different. Also, values of pH, base excess, as well as concentrations of hydrogencarbonate, sodium, potassium, calcium, glucose, urea and creatinine were not significantly different between male and female patients with diabetic ketoacidosis. In patients with diabetic ketonuria we found a correlation between admission glucose concentration and acid-base balance.
Redox imbalance caused by pesticides: a review of OPENTOX-related research
Authors: Čermak Ana Marija Marjanović , Pavičić Ivan , Želježić Davor 
Published: July 2018

Abstract
Pesticides are a highly diverse group of compounds and the most important chemical stressors in the environment. Mechanisms that could explain pesticide toxicity are constantly being studied and their interactions at the cellular level are often observed in well-controlled in vitro studies. Several pesticide groups have been found to impair the redox balance in the cell, but the mechanisms leading to oxidative stress for certain pesticides are only partly understood. As our scientific project “Organic pollutants in environment – markers and biomarkers of toxicity (OPENTOX)” is dedicated to studying toxic effects of selected insecticides and herbicides, this review is focused on reporting the knowledge regarding oxidative stress-related phenomena at the cellular level. We wanted to single out the most important facts relevant to the evaluation of our own findings from studies conducted on in vitro cell models.
Aquaporin 2 Expression in Human Fetal Kidney Development
Authors: Ráduly Gergő , Pap Zsuzsánna , Dénes Loránd , Szántó Annamária , Pávai Zoltán 
Published: July 2018

Abstract

Introduction: The metanephrogenic zone, renal cortex and renal pyramids develop into their final form by week 13. The metanephric kidney produces large quantities of diluted urine in order to maintain volumes of amniotic fluid. Aquaporins are transmembrane protein channels that enable water transport through biological membranes. Aquaporin 2 (AQP2) is a water channel found in the supranuclear region and apical area of the cell membrane of the kidneys collecting tubule cells. Its main function is reabsorption of water through vasopressin stimulation.

Materials and methods: Immunohistochemistry was used to study fetal renal tissue of 34 post-mortem fetuses of 9 weeks to 24 weeks gestational age.

Results: AQP2 expression is present in connecting tubules and collecting tubules during the targeted time period. From week 9 to 12, the expression is cytoplasmic. From week 13 to 20 the enhancement of expression in the apical cell membrane occurs with the advancement of fetal age. At the end of the studied period, from week 21 to 24, both cytoplasmic and apical expression were observed. In animal studies AQP2 expression has an increasing trend during development. In contradiction with these results, other authors described low AQP2 levels in the human fetal kidney.

Conclusions: This study helps to understand the amniotic fluid’s homeostasis during pregnancy. In the beginning of the fetal period AQP2 protein is present in the cytoplasm of epithelial cells of the collecting duct and distal connecting duct. During the fetal period, AQP2 expression in collecting ducts becomes more enhanced in the apical membrane of the cells.
Testing the validity of the Linder hypothesis for Croatia
Authors: Jošić Hrvoje , Metelko Matej 
Published: July 2018

Abstract
This paper presents empirical evidence on the validity of the Linder hypothesis in the case of Croatia. According to the Linder hypothesis, one of the new theories of international trade, countries with a similar level of income per capita should trade more. In order to investigate the trade pattern of Croatia's international trade, a panel regression model is formulated including 184 Croatia's import partner countries in the period from 2000 to 2016. The Linder effect was displayed and calculated using the Linder variable expressed as an absolute difference between GDP per capita of the importing and the exporting country. The cross-country panel regression model is estimated using Pooled OLS, Fixed and Random effects models. Results of the analysis have shown that the validity of the Linder hypothesis for Croatia cannot be accepted. Instead, the structure of Croatia's trade is in line with the gravity model of international trade.
Collection Dilemmas and Performance Measures of the Value-Added Tax in Germany and Poland
Authors: Hybka Małgorzata Magdalena 
Published: July 2018

Abstract
In the European Union Member States, value-added tax (VAT) is undergoing a continuous process of harmonization, which was initiated in the 1960s by the introduction of the First and Second Council Directives and which resulted in the implementation of the common tax assessment base. Currently, the European Union VAT system faces multiple challenges related in particular to the negative side effects of certain design features and progressing globalization. The main aim of this article is to discuss some dilemmas of the common VAT model. Particular attention is placed on the fiscal consequences of VAT preferences, as well as on the origins, components, and implications of the VAT gap. For the purpose of this analysis, 2 neighboring countries were selected, namely, Germany and Poland. On the basis of the national and Eurostat data, the author calculates the most significant VAT performance indicators and reviews the factors decreasing VAT efficiency in these countries in comparison to other European Union Member States.
Hyperbaric Oxygen Therapy (HBOT) in Pediatrics
Authors: Kuchar Ernest , Carowicz Grzegorz 
Published: July 2018

Abstract
Therapy with hyperbaric oxygen (HBOT) was first used in pediatrics in Russia in the 1920s (1927). At present, HBOT is used in children in similar indications as in adults, as well as in perinatal, neurologic and neuro-developmental conditions, even though there is only limited evidence of it offering any benefit for such conditions. The aim of this publication is to present current indications and risks of the use of HBOT in children.
Heading Control System Design for a Micro-USV Based on an Adaptive Expert S-PID Algorithm
Authors: Miao Runlong , Dong Zaopeng , Wan Lei , Zeng Jiangfeng 
Published: July 2018

Abstract
The process of heading control system design for a kind of micro-unmanned surface vessel (micro-USV) is addressed in this paper and a novel adaptive expert S-PID algorithm is proposed. First, a motion control system for the micro-USV is designed based on STM32-ARM and the PC monitoring system is developed based on Labwindows/CVI. Second, by combining the expert control technology, S plane and PID control algorithms, an adaptive expert S-PID control algorithm is proposed for heading control of the micro-USV. Third, based on SL micro-USV developed in this paper, a large number of pool experiments and lake experiments are carried out, to verify the effectiveness and reliability of the motion control system designed and the heading control algorithm proposed. A great amount of comparative experiment results shows the superiority of the proposed adaptive expert S-PID algorithm in terms of heading control of the SL micro-USV.
Steam Turbine Stage Modernisation in Front of the Extraction Point
Authors: Szymaniak Mariusz 
Published: July 2018

Abstract
The paper presents modernisation of the steam turbine stage situated in front of the turbine extraction point, based on a 225 MW turbine LP stage as an example. The modernised design is intended to better control the steam flow in this area. In the presented design a special ring is used to drive the steam leakage flow directly to the heat exchanger. The performed experiments and numerical analyses confirmed measurable exploitation and efficiency advantages of the introduced modernisation. So far, it has been successfully applied in a number of turbines working in inland power plants, but its use can be easily extended, without need for further modification and without advantage loss, to marine turbines, especially those used as main propulsion in sea-going vessels.
A New Approach of Coastal Cliff Monitoring using Mobile Laser Scanning
Authors: Ossowski Rafał , Tysiąc Paweł 
Published: July 2018

Abstract
The article proposes a new approach of coastal cliff monitoring which bases on a new comprehensive monitoring system, being a combination of mobile scanning from the sea with the geotechnical stability analysis. Mobile laser scanning is an innovative solution for 3D data collection which allows the monitored object geometry to be precisely measured, thus providing opportunities for series of analyses contributing to the development of an improved monitoring system. The authors present selected cliff profiles obtained from mobile scanning in the area of Jastrzebia Gora, complemented by relevant geotechnical analyses. The analysis of current cliff geometry is accompanied by calculations of hypothetical cliff profile changes resulting from possible action of nature forces. Finally, a comprehensive strategy for coastal cliff monitoring is proposed.
THE ANALYSIS OF NURSING STUDENT SOFT SKILLS DEVELOPMENT BETWEEN LECTURE AND PROBLEM BASED LEARNING APPROACHES 2011
Authors: Syarif Hilman 
Published: July 2018

Introduction: Student Centered Learning (SCL) is an effective method to develop student's soft skills and hard skills which are very important to support their successful carrier later. This research was conducted to identify the differences of developed soft skills between students who learn with PBL method and lecturing method. Methods: Descriptive comparative method was used in this study. The samples consisted of 15 students who learned with PBL method and 15 students who learned with lecturing method. The sample for this research was selected by random sampling method. Results: The result showed that the average of student's soft skills score in PBL method was 122.63, while student's soft skills score in lecturing method was 116.27. Discussion & Conclusion: There was significant difference of student's soft skills in PBL method and lecturing method (p value = 0.038; α = 0.05). This study recommends nursing program management, faculty of medicine at the University of Syiah Kuala keeps PBL method running and develops other methods which facilitate hard skills and soft skills are development. Keywords: nursing students, soft skill, PBL
THE APPLICATION OF TRANSCULTURAL NURSING MODEL IN PERSPECTIVE OF MADURA CULTURE IMPROVING BREASTFEEDING MOTHER’S BEHAVIOR IN JEMBER
Authors: Azza Awatiful , Susilo Cipto 
Published: July 2018

Background and objective : Breastfeeding is one of the development tasks for women after childbirth. Many factors can affect mother’s success in breastfeeding exclusively, such as family support as well as local cultural influences. This research aims to apply the transcultural nursing model in Madura cultural perspective in breastfeeding mothers.Method: This research was conducted in Public Health Centre of Pakusari Suboh Jember. The data were collected using questionnaires, and focus group discuss. The research design was question-experimental research of post test design with control by using Paired Samples Test analysis. In addition, the researchers also performed a qualitative analysis to explore the Maduranese culture. The samples were breastfeeding mothers who had infants aged 1-6 months and 50 samples were then divided into two, i.e., treatment and control groups. Also, another data source were health professionals.Result: The result showed that the maternal age range between 15-34 years with an average age of 27 years. Besides, the average of the respondents’ education background was that 60% of them did not pass elementary school, both in treatment group and control group. The results of the analysis on cultural modifications was p-value of 0.001, which means that there is the effects of applying transcultural nursing model in improving milk production.Conclusion and recomendation : An application of cultural modifications that is able to increase milk production. Therefore, it needs a good cooperation for all the components of society in supporting breastfeeding mothers by modifying less the local culture that becomes favorable for health.
CLINICAL LEARNING METHOD MIND MAPPING INCREASE CRITICAL THINKING COMPETENCE AMONG NURSING STUDENTS IN THE INTERNSHIP PROGRAM OF MEDICAL SURGICAL UNIT
Authors: Widyaningsih Susana , Hastuti Y , Mirzah S , Sujianto U 
Published: July 2018

Background: Clinical learning in internship program is a very imperative. Taking care of patients in the clinil will train the students to sharpen their critical thinking. Critical thinking competence among nursing students is important to provide a holistic nursing care. Mind Mapping is a method used in the clinical learning using a creative colorful diagram. It contains a main idea and key data of patients who were taken care of by the students in the medical surgical unit. Objective: This study aims to enhance critical thinking competence among nursing students in the intership program, medical surgical cycle. Method: The design of this study was a quasi experiment with one group pre and post test. The Mind Mapping method was given before the participants started their medical surgical clinical cycle. The guidance to develop the mind mapping (coaching) was given for approximately 60 minutes every week, for a total of 5 weeks clinical practice. The level of critical thinking competence was measured using Critical Thinking Disposition Self-Rating Form (CTDSR) which contains of 20 statements with dicotomous response. Wilcoxon Match Paired Test was used to analyse the data. Result: There 23 students enrolled in this study. Those participants were from 3 different groups. The coaching program was conducted from June-September 2016. The GPA of the respondents was above 3.0. The analysis result showed that the mean rank of post test was significantly higher than the mean rank of the pretest (Z=-2.034, P<0.05). Conclusion: The clinical learning as well as coaching in the internship program using Mind Mapping method is strongly suggested. This method will enhance the critical thinking competence among students in taking care of their patients.Key words: Mind Mapping case, Critical Thinking
THE PROVISON OF ORIENTATION TO THE ANXIETY LEVELS OF THE NEW PATIENT AT THE PONEK (OBGYN) GENERAL HOSPITAL JOMBANG
Authors: Rodiyah Rodiyah , Praningsih Supriliyah 
Published: July 2018

Introduction. Patients who first entered hospital usually has the anxiety because of hospital environment is different with their previous environment. The aim of this study was to analyze the effectof orientation to the level of anxiety in new patient in PONEK ward general hospital Jombang.Method. The type of this research was quasy experimental study with before and after with control design. The number of sample for the experimental group was 30 people control group was 30 subjects with quota sampling method. The independent variable in this study was the orientation and the dependent variable was patient’s anxiety. Research instrument used booklet. The data were processed and analyzed with the Wilcoxon sign rank test and mann whitney test, the alternative hypothesis was accepted if p<0,05.Result. Based on the analysis was of mann whitney test p- value of 0,000 is < α 0,05 this was conclude that there was an effect of new orientation to the level anxiety level of the new patients at the ponek ward general hospital jombang. Discussion. Health workers actively participate in providing orientation the new patients, therefore it can reduce the anxiety that occur when is admitted hospital and should be used as amandatory orientation program the new patient admission.Key word: providing orientation, level of anxiety, new patient.
Application of “Six Rights” on Medication Administration by Nurse and Patient Satisfaction
Authors: Kartika Imelda Rahmayunia , Melani Vivi 
Published: July 2018

Introduction: Giving the medications, nurse should pay attention to the principles of “six of rights", namely: right of patient, right medication, right dose, right way, right time, and right documentation. There are more than a half of nurses in a ward who are not provide medications in accordance with the Standard Operational Procedure (SOP). The purpose of this study was to determine of the relationship between applications of Standard Operational Procedure (SOP) six rights of medication administration by nurses and patient satisfaction. Methods: This study was using cross sectional design.There were 30 respondents taken by accidental sampling. This research was conducted in February 2017. Data collection used questionnaires and observation. Chi-Square test was used to analyze data. It can be known from 30 respondents who had six right in application of medication administration was performed good (50%) then respondents were satisfied (50%). Results: The results showed the significant relationship between the six rights of medication administration by nurse and the level of patient satisfaction (p = 0.003).Conclusion: It can be inferred that the higher interaction that occurs between nurse and patient in applying the principles of medication administration, it will higher patient satisfaction. Nurses suggested applying the six rights during medication administration.
PENINGKATAN HASIL BELAJAR MATERI PERUBAHAN PERTUMBUHAN HEWAN MELALUI METODE DISKUSI DENGAN MEDIA GAMBAR PADA SISWA KELAS II SD NEGERI BINTORO 16 SEMESTER I TAHUN PELAJARAN 2015/2016
Authors: Astuti Sri Juni 
Published: July 2018

Berdasarkan hasil temuan yang diperoleh peneliti, bahwa sebagian besar hasil belajar siswa kurang maksimal. Dari hasil analisis penguasaan butir soal tes formatif pada pembelajaran IPA tentang pertumbuhan pada hewan menunjukkan rendahnya tingkat penguasaan siswa terhadap materi pelajaran tersebut. Untuk mata pelajaran IPA hanya 3 siswa dari 16 siswa yang memperoleh nilai 62 ke atas, atau ada 18,75% yang mencapai ketuntasan belajar. Oleh karena itu, tujuan penelitian ini adalah: 1) menjelaskan peningkatan kemampuan mengidentifikasi perubahan pada pertumbuhan hewan melalui penerapan metode diskusi dan penggunaan media gambar pada siswa kelas II semester I SDN Bintoro 16 Demak; 2) mendeskripsikan perkembangan karakter keberanian siswa dalam pembelajaran mengidentifikasi perubahan pada pertumbuhan hewan melalui penerapan metode diskusi dan penggunaan media gambar. Subjek penelitian ini adalah siswa kelas II SDN Bintoro 16 Demak Tahun pelajaran 2015/2016 yang berjumlah 16 siswa. Desain penelitian adalah penelitian tindakan kelas terdiri atas dua siklus yaitu siklus I dan siklus II. Pengumpulan data diperoleh dari hasil tes, observasi, jurnal. Analisis data meliputi data kualitatif dan data kuantitatif. Berdasarkan analisis data penelitian hasil tes formatif dari siklus I ke siklus II mengalami peningkatan. Peningkatan ini dapat diketahui dari hasil tes siklus I sebesar 62,5% dan siklus II sebesar 75%, ada peningkatan sebesar 12,5% dan batas tuntas belajar secara klasikal yang memperoleh nilai lebih dari 62 lebih dari 72%. Perilaku siswa saat mengikuti kegiatan pembelajaran yaitu sebagian besar siswa sangat senang dan tertarik, lebih aktif dalam pembelajaran, sangat antusias dan serius dalam mengerjakan tugas tanpa menjumpai hal-hal yang menyulitkan sehingga hasil yang diperoleh lebih maksimal.