bluuebunny/crossref_metadata_2025_split huggingface dataset:
Türkçeyi Yabancı Dil Olarak Öğrenen Öğrencilerin Okuma Kaygıları
Authors: BAĞCI Hasan , BAZ Dilek 
Published: December 2018

Bu çalışmada, Türkçeyi yabancı dil olarak
öğrenenlerin okuma kaygı düzeylerini tespit etmek ve öğrencilerin okuma
kaygılarının cinsiyet, ana dili alfabesi, okumayı sevme durumları, okuma
alışkanlığı kazanma durumları, süreli yayın takip etme değişkenlerine göre
incelenmesi amaçlanmıştır. Çalışmada Türkçeyi yabancı dil olarak öğrenen
öğrencilerin okuma kaygısını belirlemek için Altunkaya ve Erdem (2017)
tarafından geliştirilen “Yabancı Dil Olarak Türkçe Öğrenenlere Yönelik Okuma
Kaygısı Ölçeği” kullanılmıştır.
Araştırmanın çalışma grubunu, 2017-2018 Eğitim-Öğretim yılı ikinci yarıyılında
Burdur Mehmet Akif Ersoy Üniversitesi, Malatya İnönü Üniversitesi ve Mersin
Üniversitesi Türkçe Öğretim Merkezlerinde öğrenim gören 170 yabancı uyruklu
öğrenci oluşturmaktadır. Çalışmadan elde edilen veriler spss 21.00 programı
yardımıyla istatistiki olarak değerlendirilerek bulgular, alanda yapılmış diğer
çalışmaların sonuçlarıyla karşılaştırılmış ve bu alanda çalışanlara bazı
önerilerde bulunulmuştur.
A utilidade como critério de classificação do direito e no direito
Authors: Costa Valterlei Aparecido da , Timm do Valle Maurício Dalri 
Published: December 2018

O presente artigo tem por objeto examinar as classificações do direito realizadas pela doutrina, bem como as classificações contidas no direito. E o foco principal é a utilidade como valor do ato classificatório. Para tanto, utiliza a lógica e a semiótica. Conclui que o ato lógico de classificar é a aplicação de uma diferença sobre o gênero, cujo produto é então julgado pelos pares do classificador como útil ou inútil. (Classificação do direito). Já quanto às classificações no direito, infere não serem elas realmente classificações, mas atos volitivos com função prescritiva, e não explicativa, do mundo.
Direito Fundamental à Sáude: microcefalia e políticas sanitárias para combate do Zika Virus
Authors: Maciel-Lima Sandra , Oliveira Francisco Cardozo , Domingos Isabela Moreira 
Published: December 2018

O presente artigo retrata o Direito fundamental à saúde e Políticas de Saneamento Básico como mecanismos propulsores para o desenvolvimento humano. A partir da análise do Plano de Enfrentamento Nacional para o Combate ao Vírus Zika (ZIKV), busca-se abordar a microcefalia como uma emergência sanitária de alcance global. Até a presente data, mais de 48 países já notificaram a transmissão do vírus Zika: América do Norte; América Central; Caribe e, em especial, a América do Sul, com maior número de incidência. Razão pela qual, requer a mobilização das autoridades públicas e a sociedade através de movimentos de conscientização, investimento em tecnologia, pesquisas e infraestrutura básica para a eliminação do vetor Aedes Aegypti no território brasileiro.
MODFLOW/MT3DMS Based Modeling Leachate Pollution Transfer in Solid Waste Disposal of Bahar Plain Deep Aquifer
Authors: Tizro Abdollah Taheri , Sarhadi Behzad , Mohamadi Mohamad 
Published: December 2018

Background and purpose: This paper presents a case study in simulation of process governing leachate occurrence and subsequent transport, and investigates its migration away from the landfill to control environmental adverse effects on a deep aquifer.Materials and Methods: The landfill examined in this study was an area of 240 ha and received 500 ton/day of solid waste generated from Hamedan and its surrounding including Bahar, and Jurghan. Based on the finite difference technique, leachate transport and penetration into the Hamedan plain aquifer was simulated exerting MODFLOW and MT3DMS codes in GMS Software.Results: It was concluded that landfill geological structure had the greatest influence on the transfer of urban solid waste leachate in traditional disposal sites. A low permeable conglomerate layer prohibited leachate migration to the main semi-confined aquifer. The results also indicated that urban solid waste leachate was only excited to migrate toward recharging waterways of aquifer by surface flows flooding as well as severe rainfalls.Conclusion: Geological structure of the landfill area had the greatest influence on the development of leachate pollution of municipal solid waste in traditional disposal sites. The spread of pollution to the deep aquifer near the waste disposal site was practically inhibited by an impermeable conglomerate layer in the municipal waste disposal.
Substance Use Disorders in the Elderly People Referring to Addiction Treatment Clinics, 2017
Authors: Saberi Mohammad , FaniSaberi Lale , Mousavinasab Nouroeddin , Zarghami Mehran , Taraghi Zohreh 
Published: December 2018

Background and Purpose: Addiction is regarded as a disorder of brain function. The current paper aimed at investigating the substance use disorders characteristics among elderly people.Materials and Methods: In this descriptive-correlation study, 200 elderlies referred to Amol Addiction Treatment Clinics were selected by multi-stage cluster sampling. The data collection tool was the demographic questionnaire, and alcohol, smoking, and substance involvement screening test (ASSIST) developed by the WHO. The collected data were analyzed using descriptive and inferential tests, such as independent t-test and ANOVA using SPSS Software (V.21).Results: All study sample elders (100%) consumed opioids, 65% tobacco products, 31% alcoholic beverages, and 26.5% sedatives or sleeping pills. There was a significant correlation between mean of tobacco products consumption and gender (P=0.001), income (P=0.030), and job (P<0.001). There was also a significant correlation between the mean of cannabis consumption and gender (P=0.013), and income (P=0.011). Also there was a significant correlation between mean of sedatives consumption and job (P=0.039); as well as a significant correlation between the mean of alcoholic beverages consumption and marriage (P=0.037). However, there were not documented any significant relationship between education, housing status, number of children, death of loved ones, and the severity of substance use disordersConclusion: Recognition of factors affecting substance use disorders among older people seems necessary.
Effects of Solvents on the In-vitro Antioxidant Activity of Dennettia tripetala G. Baker and Milicia excelsa (Welw.) C. Berg Root Extracts
Authors: Ekere Nwachukwu , Okparanozie Tochukwu , Agbo Matthias 
Published: December 2018

Background and Purpose: The root extracts of Dennettia tripetala G. Baker and Milicia excelsa (Welw.) C. Berg was investigated for their in-vitro antioxidant activities.Materials and Methods: The pulverized roots of Dennettia tripetala and Milicia excelsa were extracted separately by cold maceration using ethyl acetate, methanol, n-butanol and water respectively as the extracting solvents. In-vitro antioxidant, the activity of root extracts was then investigated using DPPH model. The results obtained was analyzed using One-way Analysis of Variance (ANOVA) involving GraphPad Prism 5 Software.Results: The antioxidant assay of various extracts, using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging model, revealed that the ethanol and n-butanol extracts of D. tripetala had better radical scavenging activity with IC50 values of 2.02 and 0.631 µg/mL for ethanol and n-butanol extracts, respectively. The methanol and ethanol extracts of M. excelsa showed higher radical scavenging capacity with IC50 of 0.194 and 8.84 µg/mL compared to that of the ascorbic acid which had IC50 value of 4.60 µg/mL.Conclusion: The radical scavenging ability of the extracts could be attributed to the presence of flavonoids and phenolics.
Frequency and Correlates of Sexual Dysfunction among Women Attending Outpatient Gynecological Clinics
Authors: Hamidi Madani Ali , Nargess Tavakoli Lahijani Seyedeh , Farzan Alireza , Esmaeili Samaneh , Hamidi Madani Zahra 
Published: December 2018

Background and purpose: Female sexual dysfunction (FSD) is a high-frequent multifactorial problem and may have a major effect on the quality of life. This study was conducted to investigate frequency of female sexual dysfunction and its correlated factors in women attending outpatient gynecological clinics.Methods: A total of 300 married women attending four gynecological outpatient clinics in Rasht, Iran were assessed. Sexual function was evaluated through Female Sexual Function Index (FSFI) questionnaire. Demographic characteristics, obstetric and surgical history, some medical conditions and body mass index (BMI), life style variants, knowledge about sexuality, and help-seeking behavior were assessed by a self-created questionnaire. Statistical analysis included Fisher exact test Chi-square and Spearman’s correlation coefficients.Results: 76.67% of all women in this study reported sexual dysfunction in at least one domain. The total frequency of FSD according to the low total FSFI score was 18.3%. The most frequent dysfunction was desire disorders (63.7%). The frequencies of other sexual disorders were as follows: pain disorders (35.7%), arousal disorders (34.7%), orgasmic disorders (16%), lubrication disorders (10.7%), and satisfaction disorders (10.7%). Age, number of deliveries, number of children, number of abortions, menopause, mode of delivery, episiotomy, anemia, psychiatric disease, psychotropic medication use, poor sexual knowledge, and husband’s age showed a significant statistical correlation with low total FSFI score. Women who thought they had a sexual problem involved 15.3% of all subjects, of which 67.4% have had no professional consultation about it.Conclusion: FSD is highly frequent in women referred to gynecological clinics. Thus, more attention to the state of women’s sexual health is recommended.
A Review of the Effects of Climate Change with an Emphasis on Burden of Waterborne Diseases
Authors: Gholami-Borujen Fathollahi , Ali Zazouli Mohammad , Fallahi Sahar 
Published: December 2018

Background and Purpose: Climate change has major impact on water cycle, resulting in effects on water resources, the frequency and severity of droughts, floods due to severe rainfall, natural environments, society, and economics and human health. In this paper, surveys on different models of climate change as well as the effects of climate change on the burden of waterborne diseases and also, the strengths and weaknesses of the study methodology have been reviewed.Materials and Methods: The key words “climate change”, “water borne disease”, “temperature change”, burden of disease” were used in combination with the Boolean operators “OR” and “AND”. The researchers did electronic search on PubMed, Science Direct, Springer Link, and Google Scholar. The search was conducted with publication year limitation between January 2005 to June 2017.Results: From 152 original articles, 54 papers were about modeling of climate change, 74 papers indicated the effect of climate change on infection disease, and 24 papers surveyed the water quality impact. The reviewed literature showed that, most studies had been conducted in rich countries, and the estimates of the burden of disease due to climate change were uncertain for the following reasons: 1- Uncertainty about the climate changes due to changes in greenhouse gas emissions 2- Uncertainty about the direct and indirect relationship between the climate and human health 3-Uncertainty about the relationship between climate and health as a result of socioeconomic changes in the future.Conclusion: Uncertainty in these estimates has led to little studies in this regard.
EFFECTS OF STRESS ON RISK OF ARTERIAL HYPERTENSION IN GENERAL MALE POPULATION OF 25–64 YEARS OLD: 14 YEARS OF FOLLOW UP (EPIDEMIOLOGICAL STUDY ON THE BASIS OF THE WHO PROGRAM «MONICA — PSYCHOSOCIAL»)
Authors: Gafarov V. V. , Gromova E. A. , Gagulin I. V. , Gafarova A. V. 
Published: December 2018

Objective. To study the effects of stress at home and at work on the 14-year risk of hypertension in men aged 25–64 years.Design and methods. In the framework of the WHO program «MONICA — PSYCHOSOCIAL» a screening study was performed in 1994, and 657 males aged 25–64 years (mean age — 44,3 ± 0,4 years), the citizens of Novosibirsk were included.Results. The greatest risk of hypertension was observed during the 10-year period in men experiencing stress at home (5-fold increase) and at work (6,8 times higher). Those most at risk of hypertension were the divorced and widowed men, and those with physical labor.
INTERRELATION BETWEEN POLYFUNCTIONAL MONITORING DATA IN YOUNG MEN WITH PRE- OR MILD HYPERTENSION WITH DIFFERENT BLOOD PRESSURE DAILY PROFILE
Authors: Kazidaeva E. N. , Venevtseva Yu. L. 
Published: December 2018

Objective. To examine the clinical signiﬁ cance of polyfunctional 24-hour Holter monitoring with simultaneous recording of electrocardiogram, blood pressure (BP) and respiratory efforts by respiratory inductance plethysmography (Incart, Russia) and functional features of young men with prehypertension or mild arterial hypertension with different proﬁ le of night arterial blood pressure (BP) decline («dippers», «non-dippers», «over-dippers»).Design and methods. We examined 43 adolescents and young men aged 16–26 years (mean age 19,4 ± 0,5 years). All of them underwent echocardiography («Vivid 7», GE); 48,8 % of patients were overweight or obese (body mass index, BMI > 24,9 kg/m2), and BMI was comparable in all groups. Results. Breathing disturbances (apnea/hypopnea episodes) were found in 86 % patients and were positively related with high frequency (HF) spectrum power of heart rate variability (HRV) at night-time and were not related with BMI, BP or type of night BP decline. The analysis of echocardiography revealed that in «non-dippers» (n = 18) left ventricular myocardial mass index (LVMMI) was higher (94,3 ± 16,6 g/m2) than in «over-dippers» (n = 15; 77,8 ± 10,3 g/m2, р < 0,001). In daytime «non-dippers» had lower HRV (total power spectrum and power in all three groups) and power spectrum of VLF and LF spectrum at night. The frequency of repolarization instability (transient T-wave inversion) and early repolarization syndrome was higher in «over-dippers» (66,7 %, р < 0,01). Circadian index of HR was also higher (150 %) in «over-dippers». The number of sleep apnea in «non-dippers» and «dippers» was higher (39,7 ± 29,7 and 37,1 ± 18,1 episodes per hour of sleep) than in «over-dippers» (22,3 ± 12,0 episodes per hour of sleep, р < 0,05), but the last group had more hypopneas.Conclusion. Breathing disturbances were a frequent, and, probably, physiological, ﬁ nding at polyfunctional 24-hour Holter monitoring in young overweight men with pre- or mild hypertension. There is a relationship between LVMMI and nocturnal BP dipping even in young men. Young «non-dippers» demonstrate the same clinical pattern as the older ones. «Over-dipper» type is characterized predominantly by lower HR at night and ECG repolarization abnormalities.
QUALITY OF LIFE AS A FACTOR OF CLINICAL EFFECTIVENESS OF ANTIHYPERTENSIVE THERAPY IN YOUNG MEN
Authors: Sinenkova O. Y. , Kolomeets D. V. 
Published: December 2018

Objective.To evaluate the quality of life by questionnaire SF-36 in young men of military age.Designand methods.The MOS SF-36 was used in 148 young men of military age (aged from 18 to 27 years old) for quality of life assessment.Results and conclusion.Quality of life in hypertensive subjects was worse than in healthy ones. Quality of life signifi cantly increased in most subjects after 24 weeks of antihypertensive therapy.
CIRCADIAN BLOOD PRESSURE PROFILE AND LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN CHRONIC PROSTATITIS
Authors: Zaytsev D. N. 
Published: December 2018

Objective.To study the relationship between diastolic left ventricular dysfunction and the circadian bloodpressure prof le in patients with chronic prostatitis.Design and methods.Eighty-two patients with chronic prostatitis underwent ambulatory blood pressure monitoring and echocardiography.Results and conclusion.The disturbances of circadian blood pressure profile in patients with chronic prostatitis include the abnormal nocturnal decrease in systolic and/or diastolic blood pressure, instable nocturnal systolic hypertension and an abnormality of the morning blood pressure surge. In patients with abnormal circadian blood pressure profile left ventricular diastolic dysfunction with increased myocardial mass and thickness of the posterior wall of the left ventricle was more prevalent.
HEART RATE VARIABILITY AND ENDOTHELIAL FUNCTION IN SUBJECTS WITH HYPERTENSION AND ITS ASSOCIATION WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES MELLITUS
Authors: Grigoricheva E. A. , Melnikov I. Y. 
Published: December 2018

and their relationship to nitric oxide production by endothelium.Design and methods.The study involved 141 patients with hypertension, including isolated hypertension, and associated with coronary heart disease and type 2 diabetes mellitus. Methods of investigation included the evaluation of clinical and conventional instrumentation and laboratory parameters with the additional study of heart rate variability. To assess endothelial function we determined the level of the final stable metabolites of nitric oxide: nitrite and nitrate anions (NO2 - and NO3 -) in blood plasma. Results and conclusions.According to the analysis of heart rate variability we found apparent disturbances of heart rhythm regulation in hypertensive patients: decreased overall heart rate variability, decreased amplitude of parasympathetic, sympathetic and humoral waves, reduced proportion of sympathetic, parasympathetic waves and increase of humoral waves. Co-existing diabetes mellitus led to more apparent disturbances of autonomic regulation of heart rhythm. High heart rate and low heart rate variability in hypertensive patients are associated with an increase of the final metabolites of nitric oxide in the blood plasma.
THE IMPACT OF ANTI B-CELL THERAPY ON ARTERIAL STIFFNESS IN SYSTEMIC SCLERODERMA
Authors: Maslyanskiy A. L. , Kolesovа E. P. , Penin I. N. , Cheshuina M. D. , Lapin S. V. , Konradi A. O. 
Published: December 2018

Background.Arterial wall stiffness is an independent predictor of cardiovascular mortality in different patient populations. Currently, there are several studies that show an increase of arterial wall stiffness in systemic sclerosis (SSc). The effect of immunosuppressive therapy on vascular wall stiffness in SSc patients is not investigated. The authors of this paper attempted to study the effect of rituximab and cyclophosphamide combination therapy on vascular stiffness in 5 patients with diffuse form of SSc.Design and methods.We assessed arterial stiffness in 5 patients with diffuse form of SSc before and after 6 months after combined immunosuppressive therapy.Conclusion.The parameters of arterial stiffness decreased in all patients with the moderate effect of the therapy.
A FIXED COMBINATION OF PERINDOPRIL AND AMLODIPINE IN HYPERTENSIVE PATIENTS WITH ACUTE CORONARY SYNDROME: A CLINICAL EXPERIENCE
Authors: Podolskaya A. A. , Ahmetzyanov V. F. , Aglullina E. L. 
Published: December 2018

Objective. To assess the eficacy and tolerability of a ixed combination of perindopril and amlodipine in patients with acute coronary syndrome and hypertension III stage 2 and 3 degree.Results and conclusion. The drug (perindopril plus amlodipine 10/5 mg) was shown to provide a high 24-hour antihypertensive eficacy, leading to a signiicant decrease in blood pressure and heart rate. The drug was well tolerated, and the drug withdrawal was not required.
THE RATIO OF SYSTEMIC INFLAMMATION, OXIDATIVE STRESS AND GLUTATHIONE REDOX STATUS INDICATORS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES MELLITUS
Authors: Moiseenok A. G. , Buko I. V. , Gorudko I. V. , Konstantinova E. E. , Tsapaeva N. L. , Mrochek A. G. 
Published: December 2018

Objective. To study and compare indicators of systemic inlammation and red blood cells glutathione redox potential by chronic oxidative stress (OS) in patients with coronary heart disease (CHD), type 2 diabetes mellitus (T2DM) and the combination of both diseases.Design and methods. The study included 35 patients with CHD and newly diagnosed T2DM, 109 patients with CHD, 19 patients with T2DM, and 89 healthy individuals. Systemic inlammation indicators were measured including concentration of interleukin (IL) 6 and 8, myeloperoxidase (MPO) and OS in plasma, oxidized (GSSG) and reduced (GSH) glutathione, as well as their ratio and redox potential (E), the activity of glutathione reductase (GR) and glutathione peroxidase (GP) in red blood cells.Results. Signiicant growth of systemic inlammation (IL-6, IL-8, MPO) indicators on the weakening antioxidant defense enzyme has been registered in patients with a combination of CHD and T2DM, a 3,4-fold reduction of GSH level, 5,8-fold of 2GSH/GSSH in red blood cells and E values towards the oxidized state at 36,3 mV were noted. These changes were less pronounced in CHD group and were absent in T2DM group. All subjects showed a decreased activity of GP and increased level of glycosylated hemoglobin. The correlation of E and activity GR have been found in patients with carbohydrate metabolism disorder. High positive relationship between IL concentration and red blood cells GR, E indicators has been identiied in patients with CHD and T2DM. There is a need to control and correct cellular redox potential in patients with CHD and T2DM.Conclusion. The combination of CHD and T2DM contributes to the decrease of red blood cells redox status glutathione secondary to the increased systemic inlammatory response and chronic OS indicators.
PERSONAL DETERMINANTS OF BEHAVIOR ASSOCIATED WITH HEALTH IN INDIVIDUALS WITH DIFFERENT RISK OF DEVELOPING METABOLIC SYNDROME
Authors: Dolganova N. P. , Rotar O. P. , Moguchaya E. V. , Boiarinova M. A. , Kolesova E. P. , Erina A. M. , Dubinina E. A. , Konradi A. O. , Alekhin A. N. 
Published: December 2018

Objective. To study personal characteristics affecting health behavior in individuals with different risk of metabolic syndrome (MS).Design and methods. We examined 138 respondents (aged 20–62 years) with the use of the medical examination, interview, observation and personality questionnaires (coping style, locus of control, alexithymia), and personality and behavioral characteristics of patients with different risk of MS were identiied. Results. Subjects with MS and single components of MS are characterized by emotional eating behavior, lack of sleep, lack of exercise, alexithymia, more external locus of control, avoidant coping strategies. The study showed a signiicant role of internal attitudes in the formation of health-promoting eating behavior, and the correlation between coping style and characteristics of eating behavior and smoking. Conclusion. The data support the importance of corrective measures aimed at changing not only the lifestyle, but also personal attitudes, and behavioral patterns that have an impact on health.
THE EFFECT OF THE HYPERLEPTINEMIA ON THE QUALITY OF LIFE OF HYPERTENSIVE PATIENTS WITH METABOLIC SYNDROME
Authors: Bespalova I. D. , Kalyuzhin V. V. , Medyantsev Y. A. , Osikhov I. A. , Murashev B. Y. , Ryazantseva N. V. 
Published: December 2018

Objective. To study interconnection between hyperleptinemia, the quality of life (QOL) and the severity of metabolic disorders in patients with essential hypertension with metabolic syndrome (MS). Design and methods.We have examined 46 patients with essential hypertension (blood pressure < 180/110 mm Hg), accompanied by MS. Along with complete clinical, laboratory and instrumental examination, customary in a specialized cardiologic clinic, the QOL research was carried out using MOS SF-36questionnaire. Besides, the concentration of leptin in blood serum was determined.Results and conclusions. Patients with essential hypertension with hyperleptinemia show higher intensity of clinical and laboratory markers of MS, higher activity of the systemic inlammatory response and increased QOL. A statistically signiicant inverse correlation between serum leptin level and QOL scales (SF-36) was detected.