bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Climatology of Extreme South American Andean Cold Surges
Authors: Prince Kevin C. , Evans Clark 
Published: August 2018

AbstractCold surges represent one of several phenomena by which midlatitude features can modulate the atmosphere, both dynamically and thermodynamically, deep into the tropics. This study involves the construction of a climatology of the strongest South American cold surges that follow along the Andes Mountains to quantify the extent to which these surges modulate the atmosphere from the midlatitudes to the tropics. Cold surges occurring during June–September (austral winter) from 1980 to 2017 are considered. In this study, cold-surge events are identified using standardized anomalies of 925-hPa meridional wind and 925-hPa temperature. As compared with previous cold-surge investigations, the use of standardized anomalies better enables spatial variation in cold-surge intensity and impacts to be quantified. A strong cold surge is defined as one in which the 925-hPa temperature is at least 3 standardized anomalies below 0 and the 925-hPa meridional wind is at least 3 standardized anomalies above 0 on the meso-α scale or larger. Using these criteria, 67 events are identified. The composite cold surge is characterized by highly anomalous cold, southerly flow that originates in northern Argentina and progresses northward, significantly modulating lower-tropospheric kinematic and thermodynamic fields across the entire Amazon basin over a period of 2 to as many as 8 days.
Modulation of Mean Wind and Turbulence in the Atmospheric Boundary Layer by Baroclinicity
Authors: Momen Mostafa , Bou-Zeid Elie , Parlange Marc B. , Giometto Marco 
Published: August 2018

Abstract
This paper investigates the effects of baroclinic pressure gradients on mean flow and turbulence in the diabatic atmospheric boundary layer (ABL). Large-eddy simulations are conducted where the direction of the baroclinicity, its strength, and the surface buoyancy flux are systematically varied to examine their interacting effects. The thermal wind vector, which represents the vertical change in the geostrophic wind vector resulting from horizontal temperature gradients, significantly influences the velocity profiles, the Ekman turning, and the strength and location of the low-level jet (LLJ). For instance, cold advection and positive (negative) geostrophic shear increased (decreased) friction velocity and changed the LLJ elevation. Given the baroclinicity strength and direction under neutral conditions, a simple reduced model is proposed and validated here to predict the general trends of baroclinic mean winds. The baroclinic effects on turbulence intensity and structure are even more intricate, with turbulent kinetic energy (TKE) profiles displaying an increase of TKE magnitude with height for some cases. When a fixed destabilizing surface heat flux is added, a positive geostrophic shear favors streamwise aligned roll-type structures, which are typical of neutral ABLs. Conversely, a negative geostrophic shear promotes cell-type structures, which are typical of strongly unstable ABLs. Furthermore, baroclinicity increases shear in the outer ABL and tends to make the outer flow more neutral by decreasing the Richardson flux number. These findings are consequential for meteorological measurements and the wind-energy industry, among others: baroclinicity alters the mean wind profiles, the TKE, coherent structures, and the stability of the ABL, and its effects need to be considered.
Wind Speed Measured from Underwater Gliders Using Passive Acoustics
Authors: Cauchy Pierre , Heywood Karen J. , Merchant Nathan D. , Queste Bastien Y. , Testor Pierre 
Published: August 2018

AbstractWind speed measurements are needed to understand ocean–atmosphere coupling processes and their effects on climate. Satellite observations provide sufficient spatial and temporal coverage but are lacking adequate calibration, while ship- and mooring-based observations are spatially limited and have technical shortcomings. However, wind-generated underwater noise can be used to measure wind speed, a method known as Weather Observations Through Ambient Noise (WOTAN). Here, we adapt the WOTAN technique for application to ocean gliders, enabling calibrated wind speed measurements to be combined with contemporaneous oceanographic profiles over extended spatial and temporal scales. We demonstrate the methodology in three glider surveys in the Mediterranean Sea during winter 2012/13. Wind speeds ranged from 2 to 21.5 m s−1, and the relationship to underwater ambient noise measured from the glider was quantified. A two-regime linear model is proposed, which validates a previous linear model for light winds (below 12 m s−1) and identifies a regime change in the noise generation mechanism at higher wind speeds. This proposed model improves on previous work by extending the validated model range to strong winds of up to 21.5 m s−1. The acquisition, data processing, and calibration steps are described. Future applications for glider-based wind speed observations and the development of a global wind speed estimation model are discussed.
Angle of Camera View Influences Resumption Lag in a Visual-Motor Task
Authors: Lodinger Natalie R. , DeLucia Patricia R. 
Published: August 2018

Objective: To determine whether top-view and side-view camera angles, which putatively impose different cognitive demands, differentially affect the resumption lag in a visual-motor task relevant to laparoscopic surgery. Background: Prior research showed that the time to resume a primary task after performing an interrupting task (resumption lag) increases with increases in the subjective workload of the primary task. Camera views used in laparoscopic surgery provide different views of the anatomy and have different cognitive costs and associated levels of workload. Method: Participants completed a peg transfer task while interrupted with a mental rotation task of different durations and angles of stimulus rotation. Results: Participants required significantly more time to resume the peg transfer task when using a side view than a top view and when interrupted for a longer duration. Participants’ ratings of subjective workload were consistent with these patterns of performance data; the side view resulted in longer resumption lags and was rated as greater in mental demand. Additionally, the time needed to resume the peg transfer task decreased across trials for both views. Conclusion: More time is required to resume an interrupted visual-motor task when it is more cognitively demanding than when it is less cognitively demanding possibly due to needing more time to learn the visual-motor mapping of the task higher in cognitive demand. Application: Training for laparoscopic surgery should include interruptions to allow surgeons to practice resuming a surgery-related task after an interruption and consequently shorten the time needed to resume the surgery-related task.
One-year follow-up of the XEN® implant with mitomycin-C in pseudoexfoliative glaucoma patients
Authors: Ibáñez-Muñoz Ana , Soto-Biforcos Víctor Santiago , Chacón-González María , Rúa-Galisteo Oscar , Arrieta-Los Santos Alexandra , Lizuain-Abadía María Ester , Del Río Mayor José Luis 
Published: August 2018

Purpose: To evaluate the intraocular pressure–lowering effect, the safety profile, and the success rate of the XEN45 Gel Stent (Allergan, Dublin, Ireland) in patients with pseudoexfoliative glaucoma. Methods: Retrospective study conducted on patients with pseudoexfoliative glaucoma, with or without cataract, who underwent XEN45 implantation surgery with subconjunctival mitomycin-C and had a minimum postoperative follow-up period of 12 months. The primary outcome measure was intraocular pressure reduction at 1 year as compared to baseline. Complete success was defined as a postoperative intraocular pressure reduction of ⩾20% from preoperative baseline at 12 months without any glaucoma medications. Qualified success was defined as a postoperative intraocular pressure reduction of ⩾20% at 12 months with medications. Results: Of the 24 screened patients, 21 eyes of 20 patients met the inclusion/exclusion criteria and were included in the study. A total of 13 (62%) eyes underwent XEN alone surgery and 8 (38%) eyes had combined XEN + cataract surgery. Mean intraocular pressure was significantly reduced from 21.1 (3.8) mmHg at baseline to 15.2 (3.9) mmHg at 1 year, p < 0.001. Mean antiglaucoma medications dropped from 2.95 (0.97) preoperatively to 1.23 (1.22) at month 12 (p < 0.001). Of the 21 eyes included in the study, 18 (85.7%) were considered as success, 6 (28.6%) as complete success, and 12 (57.1%) as qualified success. Five eyes required needling revision. Complications included uveitis, choroidal detachment, hyphema, and cystoid macular edema in 2, 1, 1, and 1 eye, respectively. Conclusion: XEN45 Gel Stent implant significantly reduced the intraocular pressure and the number of antiglaucoma medications in patients with pseudoexfoliative glaucoma.
Maturational Changes of Delta Waves in Monozygotic and Dizygotic Infant Twins
Authors: Vucinovic Mirjana , Kardum Goran , Vukovic Jonatan , Vucinovic Ana 
Published: August 2018

Aims: To compare developmental changes of delta 1 (0.5-2.0 Hz) and delta 2 (2.25-3.75 Hz) power spectra between healthy monozygotic (MZ) and dizygotic (DZ) twin pairs and among MZ and DZ twin groups during active/REM (AS/REM) and quiet/NREM (QS/NREM) sleep stages at 38th, 46th, and 52nd weeks of postmenstrual age (PMA). Materials and methods: Electroencephalography (EEG) recordings were analyzed using fast Fourier transforms. Differences in the developmental changes of delta power within twin pairs and between twin groups were estimated by calculating mean absolute differences of relative spectral values in delta 1 (0.5-2 Hz) and delta 2 (2.25-3.75 Hz) frequencies. Results: A review of electrodes showed that relative delta 1 power decreased, whereas delta 2 power increased from 38th toward 52nd week of PMA regardless of zygosity, sleep stages, and electrode position. Twin groups did not significantly differ ( P > .05) in within-pair MZ and DZ similarity for delta 1 and delta 2 power spectra; similarity between MZ twin partners for delta 1 and delta 2 power spectra was as high as that of DZ twin partners on each electrode position, sleep stage, and period of measurement. Conclusions: Developmental changes of delta 1 and delta 2 power spectra occurred equally in MZ and DZ twin groups during AS and QS sleep stages at 38th, 46th, and 52th PMA. The rhythm of EEG maturation evidenced by the maturation of delta 1 and delta 2 power spectra was not dependent on zygosity.
Wound Healing of the Nasal and Paranasal Mucosa: A Review
Authors: Watelet Jean-Baptiste , Bachert Claus , Gevaert Philippe , Van Cauwenberge Paul 
Published: August 2018

Background Wound healing is a highly coordinated process involving clot formation, inflammatory reaction, immune response, and, finally, tissue remodeling and maturation. Only few data regarding the specific healing of the nasal or sinusal mucosa are available. Methods After a short summary of the general principles of wound healing, the most important data regarding in vitro or in vivo models of wound healing of the nasal and paranasal mucosa are discussed. Attention is paid to clinical application. Main Findings First observations regarding the specific regulation of epithelial regeneration by growth factors have underlined the complex relationship between extracellular matrix and epithelium during the repair process. However, only poor and aspecific correlations can be described between endoscopically and histomorphologically defined postoperative phases.
The Effect of a Dissolvable Hyaluronic Acid–Based Pack on the Healing of the Nasal Mucosa of Sheep
Authors: McIntosh David , Cowin Allison , Adams Damian , Rayner Tim , Wormald Peter-John 
Published: August 2018

Introduction There is a paucity of knowledge about the healing of the nasal respiratory mucosa after endoscopic sinus surgery (ESS). Nasal packs often are placed after ESS in an attempt to reduce adhesions but the effect of these packs on the healing of the nasal mucosa is not known. Methods A standardized normal animal model (the sheep) was used to examine the healing of the nasal epithelium after ESS. A full-thickness wound was created in the nasal mucosa and either packed with a dissolvable hyaluronic acid–based pack or left unpacked to serve as control. The wounded areas were biopsied at 28, 56, 84, and 112 days postinjury and epithelialization, and cilial regeneration was assessed by light microscopy and scanning electron microscopy. Results The wounds with the dissolvable hyaluronic acid–based packs showed no differences in reepithelialization up to 84 days postwounding. However, a significant increase in reepithelialization was observed on day 84 in packed wounds compared with unpacked controls, indicating an increased rate of healing at that time point. In addition, there was a significant increase in the epithelial height in the packed wounds on day 28, indicating that packing was affecting the epithelial maturity of the mucosa. No significant difference was observed in cilial regeneration between the packed and control wounds. Conclusions Application of the hyaluronic acid–based nasal packs to wounds after ESS may improve reepithelialization of the nasal mucosa but appears to have minimal effect on reciliation at the time points studied in normal-healing wounds.
Sinus Inflammation Associated with Contralateral Inverted Papilloma
Authors: Orlandi Richard R. , Rubin Adam , Terrell Jeffrey E. , Anzai Yoshimi , Bugdaj Melissa , Lanza Donald C. 
Published: August 2018

Objective To assess with computerized tomography (CT) the association of unilateral inverted papilloma (IP) and contralateral sinus inflammation. Design Retrospective analysis of CT findings in a sample of patients with unilateral IP, a sample with other unilateral sinonasal tumors, and normal controls. Patients and Methods Sixteen patients with unilateral IP comprised the study population. Nine patients with other unilateral sinonasal tumors (five with squamous papilloma, two with squamous cell carcinoma, and one each with adenocarcinoma and large cell carcinoma) were used as a comparison population. Patients undergoing maxillofacial CT for nontraumatic orbital conditions comprised the control sample (n = 12 sides). Each patient's preoperative CT scan was evaluated with a modified Lund-Mackay scoring system. The scores for the sides opposite the IPs were compared with the sides contralateral to other sinonasal tumors as well as to normal controls. Results Analysis of all three samples’ contralateral sides simultaneously using analysis of variance revealed a difference (p = 0.010). The contralateral sinus scores in IPs tended to be higher than the sides opposite the other sinonasal tumors (mean, 2.66 ± 1.07 versus 1.18 ± 0.76; p = 0.06). These in turn were higher than the normal controls (mean, 0.75 ± 0.48; p < 0.02). Conclusions Unilateral IPs are associated with contralateral inflammation as detected by CT. This degree of contralateral inflammation is greater than that seen in other sinonasal tumors. The etiology of this association is unclear. A recent histological review suggested IP is an inflammatory polyp and not a true papilloma. Our data further suggest inflammation may be involved in the pathogenesis of IP. Further work is needed to better understand the pathophysiology and behavior of IP and to define its relationship to sinus inflammation.
Pitfalls in the Endoscopic Drainage of Subperiosteal Orbital Abscesses Secondary to Sinusitis
Authors: Noordzij J. Pieter , Harrison Scott E. , Mason John C. , Hashisaki George T. , Reibel James F. , Gross Charles W. 
Published: August 2018

Objective To review the safety and efficacy of endoscopic drainage of subperiosteal orbital abscesses (SPOAs) secondary to sinusitis and to evaluate risk factors that may be associated with failure. Study Design Retrospective chart review. Methods: All patients admitted to the University of the Virginia Health System with a diagnosis of SPOA between 1992 and 1999 were reviewed. Results Seven of the 10 SPOAs identified, each located medially, resolved without complication after endoscopic drainage. The remaining three patients required a second drainage. One patient had an inferiorly located SPOA, which recurred laterally after endoscopic drainage. A second pediatric patient, who did not undergo a routine second-look procedure, developed middle turbinate lateralization and synechiae, which led to recurrent SPOAs. A third patient with a significant history of sinusitis was found to have an ethmoid sinus mucocele extending into the medial and posterior orbit. All patients eventually resolved their symptoms. Conclusions Endoscopic drainage of medial SPOAs appears to be safe and effective. However, several risk factors must be recognized when present. Management of these risk factors is discussed.
Endoscopic Transmaxillary Biopsy of Pterygopalatine Space Masses: A Preliminary Report
Authors: Lane Andrew P. , Bolger William E. 
Published: August 2018

Introduction Although masses in the pterygomaxillary space are uncommon, they frequently present diagnostic challenges when they occur. If a tissue biopsy is required for pathological analysis, the relative inaccessibility of this region can make the surgical approach more extensive and technically difficult than seems justified. In this study, we describe a series of four cases in which a transnasal endoscopic technique was used to biopsy masses of the pterygomaxillary space. Methods The four patients described in this report had lesions of the pterygomaxillary space that were detected radiographically. The surgical approach involved an endoscopic uncinectomy and a wide maxillary antrostomy to provide maximum exposure of the posterior maxillary sinus wall. Careful opening of the bone and underlying periosteum provided ready access to the pterygomaxillary space in an atraumatic fashion. Biopsy specimens were taken under direct endoscopic visualization using traditional biopsy forceps. Results In each case, satisfactory exposure of the mass was achieved and diagnostic biopsy specimens were obtained. There were no adverse sequelae related to the procedure. One patient was returned to the operating room 2 weeks later for a repeat biopsy so that additional diagnostic studies could be performed. This was obtained easily through the previous antrostomy and posterior maxillary wall opening. Conclusions The transnasal endoscopic approach to the pterygomaxillary space is a safe, relatively noninvasive technique that can be performed by otolaryngologists trained in endoscopic sinus surgery. This procedure allows adequate exposure of the pterygomaxillary space for biopsy while avoiding the morbidity of an open surgical approach. (American Journal of Rhinology 16, 109–112, 2002)
Eosinophilia in the Ethmoid Mucosa and Its Relationship to the Severity of Inflammation in Chronic Rhinosinusitis
Authors: Szucs Eva , Ravandi Saied , Goossens Anita , Beel Mieke , Clement Peter A.R. 
Published: August 2018

Background The aim of this study was to analyze histopathologically mucosal inflammation in patients with chronic rhinosinusitis. In addition, we assessed tissue eosinophilia in relation to the severity of inflammation and to the computer tomographic (CT) findings. Methods Forty-eight pathological sinus mucosa specimens obtained during functional endoscopic sinus surgery were stained by hematoxylin and eosin. Total inflammatory cells and eosinophils were quantified. The preoperative CT scans were scored by the staging system of Lund-MacKay. Results The grade of the eosinophilic infiltration in the diseased sinus mucosa correlated significantly with the severity of the mucosal inflammation. Allergy or asthma had no effect on the proportion of the eosinophilic infiltrate. The CT scan scores assessed by the Lund-MacKay system correlated significantly with the severity of the inflammatory cellular infiltrate. The correlation between the CT scan scores and the eosinophilic infiltrate of the mucosa was close to significant. Conclusion Eosinophilic mucosal inflammation represents the most severe inflammatory changes of the mucosa. Twenty to forty percent of the patients with chronic rhinosinusitis had no eosinophilic inflammation of the mucosa. The CT-staging system of Lund-Mackay correlated with the extent of mucosal inflammation.
Electrophoretic Evaluation of Nasal Discharge in Patients with Allergic Rhinitis and Vasomotor Rhinitis
Authors: Tosun Fuat , Sezen Ilhan , Gerek Mustafa , Özkaptan Yalçın , Yapar Mehmet , Çalışkaner Zafer , Akman Serif 
Published: August 2018

Background Allergic rhinitis and vasomotor rhinitis are two common diseases that have similar symptoms and physical findings. This study was designed to assess the efficacy of electrophoretic analysis of nasal discharge for the differential diagnosis of allergic rhinitis and vasomotor rhinitis. Methods Two different groups of patients with allergic rhinitis (n = 18) and with vasomotor rhinitis (n = 18) diagnosed by current methods and 10 healthy subjects as a control group were included in this study. Component analyses of proteins in nasal wash were made by sodium dodecyl sulfate–polyacrylamide gel electrophoresis. Results The mean levels of total protein, 66-kDa proteins and 26-kDa proteins (277.2 ± 9 μ/mL, 114.5 ± 9 μg/mL, and 67.0 μ 4 μg/mL, respectively), in nasal washing samples of patients with allergic rhinitis were found to be higher than in the samples, (222.0 ± 6 μg/mL, 65.6 ± 6 μg/mL, and 42.9 ± 4 μg/mL, respectively) obtained from patients with vasomotor rhinitis. The control group showed the lowest rate of these proteins (167.8 ± 7 μg/mL, 34.3 ± 3 μg/mL, and 25.0 ± 3 μg/mL, respectively). The differences between mean levels of these proteins in all groups were statistically significant (p < 0.05). Conclusions These findings indicate that electrophoretic analysis of nasal discharge can be used for the diagnosis of allergic rhinitis and vasomotor rhinitis. However, further studies are needed to standardize the technique of nasal wash and to determine the range of proteins in nasal secretions that will confirm the diagnosis.