bluuebunny/crossref_metadata_2025_split huggingface dataset:
Increased Growth Differentiation Factor 15 Is Associated with Unfavorable Clinical Outcomes of Acute Ischemic Stroke
Authors: Yin Jieyun , Zhu Zhengbao , Guo Daoxia , Wang Aili , Zeng Nimei , Zheng Xiaowei , Peng Yanbo , Zhong Chongke , Wang Guangli , Zhou Yiting , Chen Chung-Shiuan , Chen Jing , Zhang Yonghong , He Jiang 
Published: January 2019

Abstract

BACKGROUND
Growth differentiation factor 15 (GDF-15), a stress-responsive biomarker, is known to be independently associated with mortality and cardiovascular events in different disease settings, but data on the prognostic value of GDF-15 after stroke are limited.

METHODS
Baseline serum GDF-15 was measured in 3066 acute ischemic stroke patients from the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS). The primary outcome was a composite of death and major disability within 3 months. Secondary outcomes included death, major disability, vascular events, and stroke recurrence. The associations between GDF-15 and clinical outcomes after stroke were assessed by multivariate logistic regression or Cox proportional hazards models.

RESULTS
At 3 months' follow-up, 676 (22.05%), 86 (2.80%), 81 (2.64%), and 51 (1.66%) patients had experienced major disability, death, vascular events, or stroke recurrence, respectively. After adjusting for age, sex, current smoking, alcohol consumption, and baseline National Institutes of Health Stroke Scale score, the odds ratio/hazard ratio (95% CI) of 1 SD higher of base-10 log-transformed GDF-15 was 1.26 (1.15–1.39) for primary outcome, 1.13 (1.02–1.25) for major disability, 1.79 (1.48–2.16) for death, and 1.26 (1.00–1.58) for vascular events. The addition of GDF-15 to established risk factors improved risk prediction of the composite outcome of death and major disability (c-statistic, net reclassification index, and integrated discrimination improvement, all P &lt; 0.05).

CONCLUSIONS
High GDF-15 concentrations are independently associated with adverse clinical outcomes of acute ischemic stroke, suggesting that baseline serum GDF-15 could provide additional information to identify ischemic stroke patients at high risk of poor prognosis.
The crystal structure of 4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol, C15H11ClFN3O2
Authors: Li Yong , Wu Yun-Deng , Wang Jingjing 
Published: January 2019

Abstract
C15H11ClFN3O2, monoclinic, P21/c (no. 14), a = 12.9430(8) Å, b = 9.3196(5) Å, c = 12.5959(8) Å, β = 115.861(8)° V = 1367.21(16) Å3, Z = 4, R
gt(F) = 0.0512, wR
ref(F
2) = 0.1359, T = 296(2) K.
Modeling of Relative Exergy Destruction for Turboprop Engine Components Using Deep Learning Artificial Neural Networks
Authors: Baklacioglu Tolga , Turan Onder , Aydin Hakan 
Published: January 2019

Abstract
This study illustrates an deep learning approach supported by a metaheuristic design targeting the foremost features and parameters of artificial neural network (ANN) framework used in predicting relative exergy destruction (

(

f

r
e
l
,
d
e
s
t

*

)

(f_{rel, dest}^*)

) of a turboprop components. The development of deep ANN comprising of three-hidden layers using data obtained considering multiple engine input parameters was accomplished. Once the deep learning ANN frameworks were hybridized with a metaheuristic approach, such as genetic algorithms (GAs). The analysis of errors revealed a close fit involving the predicted values of the model and references made on data in

f

r
e
l
,
d
e
s
t

∗

f_{rel, dest}^*

for the engine main components. The use of appropriately chosen values in preceding networks weights produced more accurate testing results (Linear correlation coefficient values (R) for the engine components are found to be between 0.996497 and 0.998986) in networks using three hidden layers compared to those using lower hidden layers. Furthermore, optimizing deep ANNs using GAs delivers not only further improved accuracy (R is calculated to be in the range of 0.998929–0.999966 for the engine components) but also an effective utilization of time in the resulting models.
PENGARUH KEPRIBADIAN, PENDIDIKAN KEWIRAUSAHAAN, DAN LINGKUNGAN KELUARGA TERHADAP MINAT BERWIRAUSAHA
Authors: Indriyani Lisa , Margunani Margunani 
Published: January 2019

Penelitian bertujuan ingin mengetahui apakah kepribadian, pendidikan kewirausahaan, dan lingkungan keluarga berpengaruh terhadap minat berwirausaha siswa kelas XI kompetensi keahlian akuntansi SMK N 1 Demak tahun 2018. Jenis penelitian ini adalah penelitian kuantitatif. Populasi penelitian ini adalah siswa kelas XI kompetensi keahlian akuntansi SMK N 1 Demak tahun 2018 yang berjumlah 110 siswa. Teknik pengambilan sampel menggunakan teknik sampel jenuh. Teknik pengambilan data menggunakan angket/kuesioner dan teknik analisis data menggunakan analisis statistik deskriptif dan analisis regresi berganda. Hasil penelitian ini adalah kepribadian, pendidikan kewirausahaan, dan lingkungan berpengaruh signifikan secara simultan. Kepribadian secara parsial berpengaruh signifikan, pendidikan kewirausahaan secara parsial berpengaruh signifikan, dan lingkungan keluarga secara parsial berpengaruh signifikan. Kesimpulan dari penelitian ini adalah kepribadian, pendidikan kewirausahaan, dan lingkungan keluarga berpengaruh signifikan baik secara simultan maupun secara parsial. Saran penelitian ini adalah agar guru meningkatkan kualitas pendidikan kewirausahaan yang diterima oleh siswa serta keluarga berperan dalam memberikan pengetahuan dan keterampilan berwirausaha.

This research aims to test whether there is influence between personality, entrepreneurship education, and family environment to entrepreneurial interest are the students of class XI of accountary in SMK N 1 Demak at 2018. This type of research is quantitative research. Population and sample of this research are the student student of class XI of accountary in SMK N 1 Demak at 2018 which the number is to 110 student. The technique of collecting data is using quesioner. Data analysis technique usd is descriptive statistical analysis and multiple regression analysis. The result of this research is to indicate thar personality, entrepreneurship education, and family environment simultaneously giving a significant influence to the entrepreneurship interest. Partially, personality has a significant effect on the entrepreneurship interest. Entrepreneurship education is partially significant towards the interest in entrepreneurship. Family environment significantly affects entrepreneurship interest. Conclusion of this research is that personality, entrepreneurship education, and family environment have a significant effect on entrepreneurship interest either simultaneously or partially. The suggestion of this research is that the teacher to improve the quality of entrepreneurship education received by the student as well as the family environment in giving knowledge and entrepreneurship skill.
PENGARUH PKL, LINGKUNGAN KELUARGA, AKSES INFORMASI DAN EFIKASI DIRI TERHADAP KESIAPAN KERJA
Authors: Rahmayanti Devina , Bowo Prasetyo Ari , Sakitri Wijang 
Published: January 2019

Tujuan penelitian ini adalah untuk mengetahui apakah ada pengaruh secara simultan maupun parsial antara praktik kerja lapangan, lingkungan keluarga, akses informasi, dan efikasi diri terhadap kesiapan kerja siswa kelas XII di SMK Negeri 3 Jepara Tahun Ajaran 2018/2019. Metode pengumpulan data dengan wawancara, dokumentasi,dan angket/kuesioner. Teknik analisis data menggunakan analisis statistik deskriptif dan analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa ada pengaruh positif signifikan antara praktik kerja lapangan, lingkungan keluarga, akses informasi dan efikasi diri terhadap kesiapan kerja siswa SMK sebesar 75,2%. Secara parsial menunjukkan, ada pengaruh signifikan praktik kerja lapangan terhadap kesiapan kerja siswa sebesar 10,30%, ada pengaruh signifikan lingkungan keluarga terhadap kesiapan kerja sebesar 8,52%, ada pengaruh signifikan akses informasi terhadap kesiapan kerja siswa sebesar 21,16% dan ada pengaruh signifikan efikasi diri terhadap kesiapan kerja siswa sebesar 5,24%. Saran dari penelitian ini adalah sebaiknya praktik kerja lapangan selama tiga bulan digunakan siswa sebagai bekal memasuki dunia kerja serta memperbanyak pengalaman diluar sekolah untuk meningkatkan keyakinan diri memasuki dunia kerja.

The purpose of this study is to determine wheter there is a simultaneous or partial influences beetween field work practices, family environment, acces to information, and self-efficacy to the work readiness of XII grade students at SMK Negeri 3 Jepara in 2018/2019 school year. Data collection methods were interview, documentation acces, and quwstionanaire. Data analysis techniques used desciptive statistical analysis and multiple linear regression analysis. The results show that there is a significant positive effect between field work practices, family environment, acces to information and self efficacy to the readiness of vocational studens by 75,2 %. Partially, there is a significant effect of field work practices on the student work readiness of 10,30%, there is a significant influence on family work readiness of 8,52%, there is a significant influence of information acces to student work readiness of 21,16% and there is a significant effect of self-efficacy on student job readiness of 5,24%. Suggestions from this research are: the practice of field work for three months is used by students as provisions to enter work and to increase experience outside of school to increase sefl-confidence in entering the work.
PENGARUH KEPEMIMPINAN INSTRUKSIONAL GURU DAN FASILITAS KELAS TERHADAP PRESTASI BELAJAR SISWA MELALUI MOTIVASI BELAJAR
Authors: Utari Revindi Aryandwita , Widodo Joko 
Published: January 2019

Tujuan penelitian ini adalah untuk menganalisis pengaruh kepemimpinan instruksional guru dan fasilitas kelas terhadap prestasi belajar melalui motivasi belajar. Populasi dalam penelitian ini adalah seluruh siswa kelas X IPS SMA Muahmmadiyah 1 Pati yang berjumlah 48 orang. Metode pengambilan sampel menggunakan sampel jenuh. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah dokumentasi dan angket. Teknik analisis data menggunakan analisis deskriptif dan analisis jalur. Hasil penelitian menunjukan bahwa motivasi belajar dan kepemimpinan instruksional guru berpengaruh positif dan signifikan terhadap prestasi belajar. Fasilitas kelas tidak berpengaruh signifikan terhadap prestasi belajar. Kepemimpinan instruksional guru dan fasilitas kelas berpengaruh positif dan signifikan terhadap motivasi belajar. Kepemimpinan instruksional guru dan fasilitas kelas berpengaruh positif dan signifikan terhadap prestasi belajar melalui motivasi belajar. Saran dari penelitian ini adalah guru harus memiliki kepemimpinan instruksional dalam mengelola pembelajaran di kelas dengan cara meningkatkan keterampilan mengajar. Didukung dengan fasilitas kelas yang ada seperti memanfaatkan media pengajaran sehingga pembelajaran lebih menarik. Motivasi siswa dalam belajar juga akan meningkat dan prestasi belajar yang optimal diharapkan dapat tercapai.

This study aims to analyze the effect of teacher instructional leadershipand class facilities on learning achievement through learning motivation. The population of this study was students of class X IPS SMA Muhammadiyah 1 Pati as many as 48 students. The sampling methodused saturated sampling. Data collection techniques in this study usedquestionnairesand documentation. Data analysis method used descriptive analysis and path analysis. The study results show that learning motivation and teacher instructional leadership have a positive and significant effect to learning achievement. Class facilities don’t have a significant effect to learning achievement. Teacher instructional leadership and class facilities have a positive and significant effect to learning motivation. Teacher instructional leadership and class facilities have a positive and significant effect to learning achievement through learning motivation. The suggestions of this study are the teachers should have instructional leadership in managing of classroom and improving teaching skills. They also should by support class facilities such as teaching media so that teaching and learning will be more interesting. Then, the students’ motivation will increase. Finally, the optimal learning achievement can be achieved.
Century-long expansion of hydrating cement counteracting concrete shrinkage due to humidity drop from selfdesiccation or external drying
Authors: Rahimi-Aghdam Saeed , Masoero Enrico , Rasoolinejad Mohammad , Bažant Zdeněk P. 
Published: January 2019

AbstractA physically based model for auotgenous shrinkage and swelling of portland cement paste is necessary for computation of long-time hydgrothermal effects in concrete structures. The goal is to propose such a model. As known since 1887, the volume of cement hydration products is slightly smaller than the original volume of cement and water (chemical shrinkage). Nevertheless, this does not imply that the hydration reaction results in contraction of the concrete and cement paste. According to the authors’ recently proposed paradigm, the opposite is true for the entire lifetime of porous cement paste as a whole. The hydration process causespermanent volume expansionof the porous cement paste as a whole, due to the growth of C–S–H shells around anhydrous cement grains which pushes the neighbors apart, while the volume reduction of hydration products contributes to porosity. Additional expansion can happen due to the growth of ettringite and portlandite crystals. On the material scale, the expansion always dominates over the contraction, i.e., the hydration per se is, in the bulk, always and permanentlyexpansive, while the source of all of the observed shrinkage, both autogenous and drying, is the compressive elastic or viscoelastic strain in the solid skeleton caused by a decrease of chemical potential of pore water, along with the associated decrease in pore relative humidity. As a result, the selfdesiccation, shrinkage and swelling can all be predicted from one and the same unified model, in which, furthermore, the low-density and high-density C–S–H are distinguished. A new thermodynamic formulation of unsaturated poromechanics with capillarity and adsorption is presented. The recently formulated local continuum model for calculating the evolution of hydration degree and a new formulation of nonlinear desorption isotherm are important for realistic and efficient finite element analysis of shrinkage and swelling. Comparisons with the existing relevant experimental evidence validate the proposed model.
The “Authentic Indian”: Sarah Winnemucca's Resistance to Colonial Constructions of Indianness
Authors: Humud Sarah Bonnie 
Published: January 2019

Abstract

Sarah Winnemucca, a Northern Paiute author, lecturer, interpreter, and army scout, exploited the biopolitical fiction of ‘Indian authenticity’ to claim a political, activist space for herself and her agenda. Winnemucca's work has generated a great deal of controversy over the last century. The ‘authentic Indian’ stereotypes Winnemucca engages are so intrinsic to settler colonial biopower that dealing with either her lecture series or her autobiography within the traditional binary of assimilation/tradition has been counterproductive. I argue that her work constitutes a challenge to Indigenous authenticity as a strategy of settler biopolitics.
Increasing number of stray dogs- awaited human rabies disaster in Chamba town of Himachal Pradesh
Authors: Dhiman Arvind Kumar , Dixit Pragya 
Published: January 2019

Chamba is an ancient small town of Himachal Pradesh. The town is located at an altitude of 996 metres (3,268 ft) on the bank of the Ravi River.The population town is 19930 [Census 2011]. Since it is headquarter of district, the offices of various departments are situated here. There are large numbers of temples, palaces and because of its scenic beauty there is continuous visit of tourists to this place. All these conditions lead to heavy crowd of people in the town round the year.
Investigating the Professional Competency and Reflective Practices of State Islamic Primary School English Teachers
Authors: Rahmat Hery 
Published: January 2019

Continuous teacher reflection is part of the teachers’ education literature. However, in practice, teachers rarely carry out self-reflection processes to make a number of improvements toward their professional performance. This research aimed to know (1) the professional competency of State Primary Islamic School (MIN) English teachers in Mataram in conducting learning process; (2) the reflective practice of these teachers to improve their professional competencies in conducting learning process. This is a qualitative descriptive research as it describes data of the professional competency and the reflective practice of State Primary Islamic School (MIN) English teachers in Mataram in conducting learning process. To collect data, the reseracher uses observation, interview and dokumentation. The research informen are MIN headmasters, English language teachers, and some students. The data analysis technique used (1) data reduction; (2) data verification; and (3) Conclusion. The reserach result showed that (1) the professional competency of State Primary Islamic School (MIN) English teachers in Mataram in conducting learning process is good enough. It is indicated through implementation of three learning activities (Introduction Activity, Main Activity, and Closing Activity) with the supported activities; (2) There are 3 types of reflective practice done by English teachers of State Primary Islamic School (MIN) in Mataram through learning process namely (a) the use of learning media; (b) the addition of exercise score; and (c) the chianging of exercise content.
Operative Positioning Technique for an Intertrochanteric Fracture in a Patient with an Ipsilateral Below-the-Knee Amputation
Authors: Curley Andrew J. , Chang Edward S. 
Published: January 2019

Case:
A 56-year-old man with a remote history of a left below-the-knee amputation (BKA) presented to the emergency department with an ipsilateral intertrochanteric fracture (IT). This case produced an operative challenge because commonly used intraoperative traction methods could not be applied to a patient with a BKA.

Conclusion:
We describe a rarely utilized surgical technique of applying traction to an amputated extremity through an inverted boot on a fracture table during open reduction and internal fixation of an IT.
Unusual Horizontal Patellar Dislocation Reduced without General Anesthesia
Authors: Uluyardımcı Enes , Bozkurt İbrahim , Öçgüder Durmuş Ali , Yalçın Nadir 
Published: January 2019

Case:
Horizontal patellar dislocation is a rare clinical event, and there is no consensus on its management. We describe 2 relatively elderly patients with 2 different types of horizontal patellar dislocation who were successfully treated with closed reduction without general anesthesia.

Conclusion:
Appropriate and gently managed closed reduction without general anesthesia may be successful in cases of acute horizontal patellar dislocation, provided there are no osteophytes or an injury that requires surgical treatment. With closed reduction and subsequent rehabilitation, patients can regain functional capacity quickly.
A Desmoid Tumor Involving the Subscapularis Muscle
Authors: Ballatori Sarah E. , Hecht Jonathan L. , Lozano-Calderón Santiago A. 
Published: January 2019

Case:A 31-year-old woman developed worsening pain and paresthesia in the neck, shoulder, and arm over a period of 6 years. Magnetic resonance imaging revealed a soft-tissue mass in the subscapular region, with likely involvement of the scapula and the subscapularis muscle. The mass was resected, and the final histologic diagnosis was desmoid-type fibromatosis.Conclusion:Desmoid tumors with subscapularis muscle involvement are exceedingly rare. Although limited range of motion is the more common presentation for these tumors, this case demonstrates that desmoid tumors may present with primarily neurologic symptoms.
Trial Summary on the Comparison of Various Non‐Aflatoxigenic Strains of Aspergillus flavus on Mycotoxin Levels and Yield in Maize
Authors: Molo Megan S. , Heiniger Ron W. , Boerema Leah , Carbone Ignazio 
Published: January 2019

Core Ideas

Biocontrol strains are effective at reducing AF levels in maize.
Native and commercially available biocontrol strains are equally effective in reducing AF levels.
Deploying strains of opposite mating types in combination can lead to the greatest reduction in AF contamination.
The fungus Aspergillus flavus can contaminate maize (Zea mays L.) by producing aflatoxins (AFs), secondary metabolites that have been shown to have adverse health impacts for humans and animals when ingested in large quantities or over extended lengths of time. The FDA strictly regulates that corn contaminated with more than 20 parts per billion (ppb) AFs cannot be marketed for human consumption; therefore, AFs cost US corn growers billions of dollars every year. Current methods to curb aflatoxin contamination in fields involve dense applications of non‐aflatoxigenic biological control (biocontrol) strains, either Afla‐Guard or AF36, that outcompete native strains and reduce toxicity levels throughout the field. This fungus is heterothallic and sexual reproduction occurs between isolates of opposite mating types, either MAT1−1 or MAT1−2. Both biocontrol strains are of a single mating type MAT1−2. The implications of adding a strain of opposite mating type (MAT1−1) to this formulation are unknown. Here we examine the ability of native non‐aflatoxigenic strains applied singly and in combination to reduce AF concentrations in a cornfield in Rocky Mount, NC. We show that native, non‐aflatoxigenic A. flavus strains reduced aflatoxin levels and increased yield when compared with untreated controls. Moreover, the strain formulations that included sexually compatible MAT1−1 and MAT1−2 strains showed the greatest reduction in aflatoxin levels. We propose that using a combination of native isolates of opposite mating types reduces AF levels further than current biocontrol agents of a single mating‐type strain and could potentially provide a more long‐term form of control.
O efeito da governança tributária sobre o custo de capital das empresas brasileiras
Authors: Moreira Caritsa Scartaty , Silva Maurício Correa 
Published: January 2019

O mercado acionário brasileiro vive em crescimento constante, porém há conflitos de interesses entre o principal e o agente quanto à gestão dos recursos aplicados, que por sua vez originam o problema de agência. Então, a relação entre esse cenário de conflitos e a complexidade e obscuridade do sistema tributário brasileiro está diretamente relacionada ao investidor, uma vez que este busca o maior retorno possível de seus investimentos. Desse modo, boas práticas de governança tributária para a redução da carga tributária incidente sobre o lucro das companhias, pode ser uma estratégia a ser utilizada pelas empresas para reduzir a taxa mínima de retorno demandada pelos acionistas. Assim, esta pesquisa buscou analisar o efeito da Governança Tributária sobre o custo de capital próprio das empresas brasileiras listadas na B3. A amostra final resultou em um painel balanceado formado por 300 observações, cuja análise compreendeu 60 empresas no período de 2012 a 2016. Os dados analisados foram extraídos da Bloomberg® e do Formulário de Referência disponível no sítio eletrônico do Brasil, Bolsa e Balcão (B3). A metodologia utilizada foi a regressão múltipla do tipo pooled. Os resultados encontrados sugerem que as boas práticas de governança tributária influenciam, estatística e positivamente, o custo de capital das empresas brasileiras, isto é, à medida que não há redução dos fluxos de caixa provenientes do pagamento de tributos, os investidores aumentam a taxa de retorno esperada dos investimentos realizados. Concluindo, que a variação no custo de capital próprio das empresas pode ser explicada pela adoção da governança tributária.