bluuebunny/crossref_metadata_2025_split huggingface dataset:
C’est la vie ! Quatorze années de détention politique
Authors: Tedjabayu  , Chambert-Loir Traduit et introduit par Henri 
Published: June 2019

Cet article présente deux extraits des mémoires de Tedjabayu, qui a passé quatorze ans en prison, à Java, et au bagne de Buru, entre 1965 et 1979. Tedjabayu est l’aîné des huit enfants de Sudjojono et Mia Bustam. Il avait 21 ans lorsqu’il a été arrêté ; il était étudiant en géographie à l’Université Gadjah Mada et membre du CGMI (Fédération des mouvements étudiants d’Indonésie, d’obédience communiste). Les mémoires, inédits jusqu’à aujourd’hui, ont été écrits en 2014-2017 ; ils sont accompagnés d’un journal, tenu à Buru en 1978‒1979. Ce texte constitue un document important sur la vie à Buru, à côté de la douzaine de souvenirs déjà publiés sur ce bagne, où le régime de Soeharto envoya 12.000 hommes entre 1969 et 1979. En dépit de tous les mauvais traitements qu’il a subis, Tedjabayu relate ses années de détention avec la volonté de toujours privilégier la beauté de la nature, le bonheur de l’amitié et l’émerveillement de vivre.
SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses
Authors: Tomic Adriana , Tomic Ivan , Rosenberg-Hasson Yael , Dekker Cornelia L. , Maecker Holden T. , Davis Mark M. 
Published: June 2019

AbstractMachine learning holds considerable promise for understanding complex biological processes such as vaccine responses. Capturing interindividual variability is essential to increase the statistical power necessary for building more accurate predictive models. However, available approaches have difficulty coping with incomplete datasets which is often the case when combining studies. Additionally, there are hundreds of algorithms available and no simple way to find the optimal one. In this study, we developed Sequential Iterative Modeling “OverNight” (SIMON), an automated machine learning system that compares results from 128 different algorithms and is particularly suitable for datasets containing many missing values. We applied SIMON to data from five clinical studies of seasonal influenza vaccination. The results reveal previously unrecognized CD4+ and CD8+ T cell subsets strongly associated with a robust Ab response to influenza Ags. These results demonstrate that SIMON can greatly speed up the choice of analysis modalities. Hence, it is a highly useful approach for data-driven hypothesis generation from disparate clinical datasets. Our strategy could be used to gain biological insight from ever-expanding heterogeneous datasets that are publicly available.
Capturing Upper Limb Gross Motor Categories Using the Kinect® Sensor
Authors: Seo Na Jin , Crocher Vincent , Spaho Egli , Ewert Charles R. , Fathi Mojtaba F. , Hur Pilwon , Lum Sara A. , Humanitzki Elizabeth M. , Kelly Abigail L. , Ramakrishnan Viswanathan , Woodbury Michelle L. 
Published: June 2019

AbstractImportance: Along with growth in telerehabilitation, a concurrent need has arisen for standardized methods of tele-evaluation.Objective: To examine the feasibility of using the Kinect sensor in an objective, computerized clinical assessment of upper limb motor categories.Design: We developed a computerized Mallet classification using the Kinect sensor. Accuracy of computer scoring was assessed on the basis of reference scores determined collaboratively by multiple evaluators from reviewing video recording of movements. In addition, using the reference score, we assessed the accuracy of the typical clinical procedure in which scores were determined immediately on the basis of visual observation. The accuracy of the computer scores was compared with that of the typical clinical procedure.Setting: Research laboratory.Participants: Seven patients with stroke and 10 healthy adult participants. Healthy participants intentionally achieved predetermined scores.Outcomes and Measures: Accuracy of the computer scores in comparison with accuracy of the typical clinical procedure (immediate visual assessment).Results: The computerized assessment placed participants’ upper limb movements in motor categories as accurately as did typical clinical procedures.Conclusions and Relevance: Computerized clinical assessment using the Kinect sensor promises to facilitate tele-evaluation and complement telehealth applications.What This Article Adds: Computerized clinical assessment can enable patients to conduct evaluations remotely in their homes without therapists present.
Onomástica Turca
Authors: Boray Sibel 
Published: June 2019

Después de que entrase en vigor la “Ley del apellido” en 1934, todos los ciudadanos turcos empezaron a llevar nombre y un apellido. El nombre podía contener varias palabras pero el apellido tenía que ser una única palabra. Según esta ley el padre de cada familia tenía que elegir un apellido para su familia.
En este artículo se estudia las preferencias de la elección de los nombres entre los ciudadanos de la República de Turquía hoy en día.
Mamluk Popular Tales and Political Nostalogia
Authors: Shaikh Ahmad Khaled 
Published: June 2019

Remarks on Jane Hathaway’s "nostalgia" theory (see infra, n. 6) concerning the impression left by the Mamluk sultans left on historiography. Our remarks are based on manuscripts (especially the unpublished BNF arabe 3651) that did not become part of The Arabian Nights but help in understanding how that collection formed and took shape.
Normanitas and Memorial Traditions in the Apulian Architecture of Emperor Frederick II
Authors: Nancarrow Jane-Heloise 
Published: June 2019

ABSTRACT
From 1225 to 1250, Frederick II, Holy Roman Emperor, built or renovated at least seventy defensive structures in the southern Italian province of Apulia. These buildings blended Roman, Islamic, or Byzantine elements with newer Gothic architecture; however, many of these architectural traits had already been adapted by the Norman lords of southern Italy in the preceding two centuries. Thus we must consider Frederick's originality in light of this less studied trend in the existing Romanesque canon. Frederick's replication of Norman architectural practices was based on the fact that they previously been used as a tool of empire, and it echoes his reuse of Roman remains. This article considers several aspects of Frederick's architectural program, including topographical layout and geographical positioning, his appropriation of Roman and Norman remains, and his adoption of classical and Norman artistic and engineering practices as nuanced processes of architectural spoliation and innovation.
The Theory and Practice of War and Government Practiced by King Pere III “the Ceremonious” of Aragon (1336–87)
Authors: Kagay Donald J. 
Published: June 2019

ABSTRACT
This article focuses on the development of war theory during the thirteenth and fourteenth centuries and how it affected the practical ruling philosophy of one Iberian king—Pere III of Aragon (r. 1336–87). Though familiar with the many warfare manuals of his era, Pere was directly influenced by the religious work of his uncle, Prince Pere d'Aragó (1305–81) and the chivalric autobiography of his great-great grandfather, Jaume I (r. 1214–76). King Pere III used these works to better understand war and to try to improve his own performance as both king and commander, both of which avocations he thought and wrote about in great detail.
Russian definitional generic sentences
Authors: Seres Daria , Espinal M.Teresa 
Published: June 2019

In this article we analyse Russian definitional sentences, which are a type of generic sentence. We focus on the structure and meaning of canonical definitions, which express an identity/identification relation between two nominal concepts. In Russian such definitions are given in the form of a bi-nominative structure: NP1 – èto NP2 (‘NP1 is NP2’). We argue that definitional sentences are copular, and they are non-predicational, showing similarities to equative, identificational and specificational sentences. We also argue that (i) both NPs in definitional sentences are kind-referring, whereas èto is non-referential; (ii) a copula be maps a kind entity (the denotation of NP2) to itself (identity function); and (iii) the neuter element èto introduces a presentational function that maps the kind entity in postcopular position to a function that looks for another kind entity (the one corresponding to NP1) and composes a definitional generic sentence.
Stochastic and deterministic drivers of seasonal variation of fungal community in tobacco field soil
Authors: Li Xing , Li Tianming , Meng Delong , Liu Tianbo , Liu Yongjun , Yin Huaqun , Deng Jie , Zeng Songrong , Shen Li 
Published: June 2019

Background
The soil fungal community plays an important role in global carbon cycling and shows obvious seasonal variations, however, drivers, particularly stochastic drivers, of the seasonal variation in the fungal community have never been addressed in sufficient detail.

Methods
We investigated the soil fungal community variation between summer growing (SG) and winter fallow (WF) stage, through high throughput sequencing of internal transcribed spacer (ITS) amplicons. Subsequently, we assessed the contribution of different ecological processes to community assembly using null-model-based statistical framework.

Results
The results showed that the fungal community diversity decreased significantly after tobacco cropping in the SG stage and the composition showed a clear turnover between the WF and SG stages. The variation in community composition was largely attributable to the presence of a small portion of Dothideomycetes in the WF stage that dominated the soil fungal community in the SG stage. The organic matter, temperature, and water content were the main deterministic factors that regulated the fungal community; these factors explained 34.02% of the fungal community variation. Together with the result that the fungal community was mainly assembled by the dispersal process, our results suggested that the stochastic factors played important roles in driving the seasonal variation of fungal community. The dispersal limitation dominated the fungal community assembly during the WF stage when homogenizing dispersal was the main assembly process of the fungal community in the SG stage. Thus, we proposed that the dispersal processes are important drivers for seasonal variation of fungal community in tobacco planted soil.
Association between complementary and alternative medicine use and prolonged time to conventional treatment among Thai cancer patients in a tertiary-care hospital
Authors: Chotipanich Adit , Sooksrisawat Chulaporn , Jittiworapan Benjamabhon 
Published: June 2019

Objectives
The purpose of this study is to investigate the patterns of complementary and alternative medicine use and its association with time to conventional treatment.

Design
A cross-sectional study design was designed.

Setting and participants
The study was performed at the Chonburi Cancer Hospital, with chart reviews and interviews performed for 426 patients with various cancers between May and December 2018.

Results
The results indicated that 192 of the 426 patients (45.1%) reported using complementary and alternative medicines; herbal products were the most common type. Approximately 34.3% of these medicines involved unlabeled herbal products with unidentifiable components. The rates of complementary and alternative medicine use were significantly elevated for men and patients with stage IV cancer. The multivariable linear regression analysis of the relationship between factors and the time until conventional treatment was received revealed that the regression coefficient of the use of complementary and alternative medicine was 56.3 (95% confidence interval [27.9–84.6]). This coefficient reflected an additional 56.3 days of time until conventional treatment, relative to patients who did not use complementary and alternative medicine.

Conclusions
The present study revealed that complementary and alternative medicine use was fairly common among Thai patients with cancer and was associated with a prolonged time to receiving conventional treatment.
Do intraspecific life history patterns follow interspecific predictions? A test using latitudinal variation in ringed seals
Authors: Ferguson Steven H. , Yurkowski David J. , Young Brent G. , Willing Cornelia , Zhu Xinhua , Muir Derek C. G. , Fisk Aaron T. , Thiemann Gregory W. 
Published: June 2019

AbstractMammals adapted to unpredictable and low‐energy environments often evolve a “bet‐hedging” life history strategy characterized by less costly reproductive outputs over a longer and slower‐growing life. In contrast, species adapted to more predictable (i.e., low variation) and higher energy environments may evolve greater fecundity over a shorter and faster‐growing life. We tested whether this known interspecific pattern also occurs within a species. We compared life history traits of the ringed seal (Pusa hispida) in the Canadian High Arctic to those closer to the southern limit of the species' circumpolar distribution. We found that northern seals grew slower than southern seals (Brody growth coefficient), achieved a greater asymptotic body weight (82 and 69 kg vs. 74 and 54 kg female and male, respectively), reached sexual maturity later (6.1 years vs. 4.5 years), had lower fecundity (1.8 years vs. 1.3 years interbirth interval), longer average lifespan (5 years vs. 3 years median age), and greater movements (1,269 vs. 681 km). Mating systems also likely differed with northern seals showing morphological evidence of a promiscuous mating system with potential sperm competition as indicated by greater relative testes size. The northern region was also characterized by more unpredictable environmental timing of seasonal events, such as spring sea ice breakup. Life history variation between the intraspecific groups of seals appears to agree with interspecific patterns and provides a better understanding of how species' life history parameters shift in concert with environmental conditions.
Mutations in TOP2B cause autosomal‐dominant hereditary hearing loss via inhibition of the PI3K‐Akt signalling pathway
Authors: Xia Wenjun , Hu Jiongjiong , Ma Jing , Huang Jianbo , Jing Tianrui , Deng Lisha , Zhang Jin , Jiang Nan , Ma Duan , Ma Zhaoxin 
Published: June 2019

Hereditary hearing impairment is a clinically and genetically heterogeneous disease. Whole‐exome sequencing was performed on seven affected and six unaffected members in a large Chinese family with autosomal‐dominant nonsyndromic hearing loss. The pathogenic variant of the gene encoding human topoisomerase IIβ TOP2B (c.G4837C:p.D1613H) was cosegregated with hearing loss in this pedigree and another two variants of TOP2B were detected in 66 sporadic patients with hearing loss. top2b knockdown led to significant defects in zebrafish inner ears and caused downregulation of akt which resulted in inactivation of PI3K‐Akt signalling. As a result, supporting cell and hair cell numbers were reduced through inhibition of the PI3K‐Akt pathway. Therefore, we hypothesized that mutations in TOP2B can cause autosomal‐dominant nonsyndromic hearing impairment through inhibition of the PI3K‐Akt signalling pathway.DatabaseThe whole‐exome sequence data in the study are available at the Sequence Read Archive database (NCBI) under the accession numbers SRR9050868, SRR9050867, SRR90508676, SRR90508675, SRR90508674, SRR90508673, SRR90508672, SRR90508671, SRR90508679, SRR90508670, SRR9050859. SRR9050858 and SRR9050857, respectively.
Validity and Reliability of Screening Measures for Depression and Anxiety Disorders in Rheumatoid Arthritis
Authors: Hitchon Carol A. , Zhang Lixia , Peschken Christine A. , Lix Lisa M. , Graff Lesley A. , Fisk John D. , Patten Scott B. , Bolton James , Sareen Jitender , El‐Gabalawy Renée , Marriott James , Bernstein Charles N. , Marrie Ruth Ann 
Published: June 2019

ObjectiveTo test the validity and reliability of screening instruments for depression and anxiety in rheumatoid arthritis (RA).MethodsParticipants with RA completed the Patient Health Questionnaire (PHQ‐2 or PHQ‐9), the Patient Reported Outcomes Measurement Information System depression short form 8a and anxiety short form 8a, the Hospital Anxiety and Depression Scale anxiety score (HADS‐A) and depression score (HADS‐D), the Overall Anxiety Severity and Impairment Scale, the Generalized Anxiety Disorder 2‐ and 7‐item scales, and the Kessler‐6 scale. Clinical depression and anxiety disorders were confirmed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I Disorders (SCID‐1) research version. We reported sensitivity, specificity, positive predictive value, and negative predictive value using SCID‐1 diagnoses as the criterion standard. Test–retest reliability was assessed with the intraclass correlation coefficient.ResultsOf 150 participants, 11.3% had SCID‐1–diagnosed depression, 7.3% had SCID‐1–diagnosed generalized anxiety disorder, and 19.3% had any SCID‐1–diagnosed anxiety disorder. For depression, sensitivity ranged from HADS‐D (cut point 11; 35%) to PHQ‐2 (88%) and PHQ‐9 (87%). Specificity ranged from PHQ‐9 (77%) and PHQ‐2 (84%) to HADS‐D (cut point 11; 94%). Positive predictive value ranged from 30% to 43%. Negative predictive value ranged from 92% to 98%. For generalized anxiety disorder, sensitivity ranged from HADS‐A (cut point 11; 45%) to HADS‐A (cut point 8; 91%). Specificity ranged from 81% to 89% for all measures except the HADS‐A (cut point 8; 63%). Intraclass correlation coefficient estimates ranging from 0.69 to 0.88 confirmed good test–retest reliability.ConclusionDepression screening instruments had good diagnostic performance; anxiety instruments were more variable. Identified depression and anxiety require clinical confirmation.
Photo‐Fenton‐like Metal–Protein Self‐Assemblies as Multifunctional Tumor Theranostic Agent
Authors: Li Tianliang , Zhou Jia , Wang Lirui , Zhang Hanfu , Song Cunfeng , de la Fuente Jesús M. , Pan Yunxiang , Song Jie , Zhang Chunlei , Cui Daxiang 
Published: June 2019

AbstractEmerging Fenton‐like activity of copper ions has inspired great exploration for tumor microenvironment‐activated tumor therapy due to the toxic ·OH production for chemodynamic therapy and extra oxygen generation for photodynamic therapy (PDT). Still, the ·OH produced by copper ions is not satisfied even when copper ions are placed in a low pH environment (pH ≈ 5.0). To amplify its Fenton‐like activity, in this work, one kind of Cu2+–protein self‐assemblies (C‐m‐ABs) loaded with photosensitizer indocyanine green (ICG) is constructed, which can catalyze H2O2 generating more amounts of ·OH under light irradiation once Cu2+ is reduced to Cu+ by glutathione. Such fantastic phenomena confirms that C‐m‐ABs can act as a photo‐Fenton‐like agent. Furthermore, C‐m‐ABs can dramatically accelerate O2 generation (catalase activity) to enhance the PDT of ICG. After loading with the anticancer drug doxorubicin, C‐m‐ABs are further self‐assembled into novel nanobelts, which simultaneously exhibit superior photo‐heat conversion effects, enhanced r1 relaxation (21.416 s−1 mm−1) and stimuli‐responsive drug release behaviors. High cytotoxicity in vitro, effective tumor accumulation capacity observed by fluorescence/photoacoustic/magnetic resonance imaging, and enhanced chemo‐/photodynamic/photothermal therapeutic performance are achieved. Based on these results, a photo‐Fenton‐like metal–protein self‐assemblies demonstrate great potential for tumor theranostics.
Human Ocular Angiogenesis‐Inspired Vascular Models on an Injection‐Molded Microfluidic Chip
Authors: Ko Jihoon , Lee Younggyun , Lee Somin , Lee Seung‐Ryeol , Jeon Noo Li 
Published: June 2019

AbstractAngiogenic sprouting, which is the growth of new blood vessels from pre‐existing vessels, is orchestrated by cues from the cellular microenvironment, such as spatially controlled gradients of angiogenic factors. However, current in vitro models are less scalable for in‐depth studies of angiogenesis. In this study, a plastic‐based microfluidic chip is developed to reconstruct in vitro 3D vascular networks. The main disadvantages of the preexisting system are identified, namely, the low productivity and difficulty of experiments, and a breakthrough is suggested while minimizing disadvantages. The selection of plastic materials contributes to the productivity and usability of in vitro devices. By adopting this material, this chip offers simple fluid patterning, facilitating the construction of a cell‐culture microenvironment. Compared with previous systems, the chip, which can form both inward and outwardly radial vascular sprouting, demonstrates the growth of functional, morphologically integral microvessels. The developed angiogenic model yields dose‐dependent results for antiangiogenic drug screening. This model may contribute significantly not only to vascular studies under normal and pathological conditions, but also to fundamental research on the ocular neovascularization. Furthermore, it can be applied as a tool for more practical, extended preclinical research, providing an alternative to animal experiments.
Molecular Beam Epitaxy Scalable Growth of Wafer‐Scale Continuous Semiconducting Monolayer MoTe2 on Inert Amorphous Dielectrics
Authors: He Qingyuan , Li Pengji , Wu Zhiheng , Yuan Bin , Luo Zhongtao , Yang Wenlong , Liu Jie , Cao Guoqin , Zhang Wenfeng , Shen Yonglong , Zhang Peng , Liu Suilin , Shao Guosheng , Yao Zhiqiang 
Published: June 2019

AbstractMonolayer MoTe2, with the narrowest direct bandgap of ≈1.1 eV among Mo‐ and W‐based transition metal dichalcogenides, has attracted increasing attention as a promising candidate for applications in novel near‐infrared electronics and optoelectronics. Realizing 2D lateral growth is an essential prerequisite for uniform thickness and property control over the large scale, while it is not successful yet. Here, layer‐by‐layer growth of 2 in. wafer‐scale continuous monolayer 2H‐MoTe2 films on inert SiO2 dielectrics by molecular beam epitaxy is reported. A single‐step Mo‐flux controlled nucleation and growth process is developed to suppress island growth. Atomically flat 2H‐MoTe2 with 100% monolayer coverage is successfully grown on inert 2 in. SiO2/Si wafer, which exhibits highly uniform in‐plane structural continuity and excellent phonon‐limited carrier transport behavior. The dynamics‐controlled growth recipe is also extended to fabricate continuous monolayer 2H‐MoTe2 on atomic‐layer‐deposited Al2O3 dielectric. With the breakthrough in growth of wafer‐scale continuous 2H‐MoTe2 monolayers on device compatible dielectrics, batch fabrication of high‐mobility monolayer 2H‐MoTe2 field‐effect transistors and the three‐level integration of vertically stacked monolayer 2H‐MoTe2 transistor arrays for 3D circuitry are successfully demonstrated. This work provides novel insights into the scalable synthesis of monolayer 2H‐MoTe2 films on universal substrates and paves the way for the ultimate miniaturization of electronics.