bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mild water stress-induced priming enhance tolerance to Rosellinia necatrix in susceptible avocado rootstocks
Authors: Martínez-Ferri Elsa , Moreno-Ortega Guillermo , Berg Noelani van den , Prieto Clara Pliego 
Published: July 2019

Abstract
Background: White root rot (WRR) disease caused by Rosellinia necatrix is one of the most important threats affecting avocado orchards in temperate regions. The eradication of WRR is a difficult task and environmentally friendly control methods are needed to lessen its impact. Priming plants with a stressor (biotic or abiotic) can be an strategy to enhance plant defense/tolerance against future stress episodes but, despite the known underlying common mechanisms, few studies use abiotic-priming for improving tolerance to forthcoming biotic-stress and vice versa (‘cross-factor priming’). To assess whether cross-factor priming can be a potential method for enhancing avocado tolerance to WRR disease, ‘Dusa’ avocado rootstocks, susceptible to R. necatrix, were subjected to two levels of water stress (mild-WS and severe-WS) and, after drought-recovery, inoculated with R. necatrix. Physiological response and expression of plant defense related genes after drought-priming as well as the disease progression were evaluated.
Results: Water stressed avocado plants showed lower water potential and stomatal limitations of photosynthesis compared to control plants. In addition, NPQ and qN values increased, indicating the ongoing of energy dissipating mechanisms closely related to the relief of oxidative stress. This response was proportional to the severity of the water stress and was accompanied by the deregulation of pathogen defense related genes in the roots. After re-watering, leaf photosynthesis and plant water status recovered rapidly in both treatments, but roots of mild-WS primed plants showed a higher number of overexpressed genes related with plant defense than severe-WS primed plants. Disease progression after inoculating primed-plants with R. necatrix was significantly delayed in mild-WS primed plants.
Conclusions: These findings demonstrate that mild-WS can induce a primed state in the WRR susceptible avocado rootstock ‘Dusa’ and reveal that ‘cross-factor priming’ with water stress (abiotic stressor) is effective for increasing avocado tolerance against R. necatrix (biotic stressor), underpinning that plant responses against biotic and abiotic stress rely on common mechanisms. Potential applications of these results may involve an enhancement of WRR tolerance of current avocado groves and optimization of water use via low frequency deficit irrigation strategies.
Risk factors associated with Fatal Dengue Hemorrhagic Fever in Adults; A case control study
Authors: Medagama Arjuna , Dalugama Chamara , Meiyalakan Gukes , Lakmali Darshani 
Published: July 2019

Abstract
Background

Dengue is endemic in most parts of the tropics with a significant mortality of 1-5%. Although individual case reports and case series have been published, large-scale case controls studies are few. The objective of this study was to find clinical and laboratory predictors of mortality in dengue.

Methods

Hospital case record based case control study was performed.

Results

Twenty fatalities with 80 controls were analyzed. Clinical parameters of postural dizziness (OR 3.2; 95% CI 1.1 - 8.9), bleeding (OR 31.9; 95% CI 6.08 - 167.34), presence of plasma leakage (OR 64.6; 95% CI 7.45 – 560.5), abdominal tenderness (OR 2.24; 95% CI 0.79 – 6.38) and signs of cardio-respiratory instability at admission increased the risk of dying from dengue. Altered consciousness was exclusively seen in 20% of cases. Laboratory parameters of elevated CRP (OR 1.652; 95% CI 1.28 – 2.14), AST or ALT> 500IU/L (OR 52.5; 95% CI 12.52 – 220.1) and acute kidney injury (AKI) (OR 103.5; 95% CI 13.26 – 807.78) during hospital stay increased the odds of dying. Need for assisted ventilation and multi organ dysfunction (MOD) were exclusively seen in the cases. Multivariate logistic regression revealed bleeding at admission, AKI and elevated hepatic transaminase >500IU/L to be independent predictors of mortality.

Conclusions

This case-control study revealed that mortality from dengue could be predicted using clinical parameters at admission and low cost routine laboratory investigations.
Association of Central Serous Chorioretinopathy with single-nucleotide polymorphisms in Complement Factor H Gene in a Chinese population
Authors: linghu dandan , xu hui , cao yu , qu jinfeng , jin enzhong , gao tingting , yao yuou , huang lvzhen , zhao mingwei 
Published: July 2019

Abstract
Background: To analyze the association between central serous chorioretinopathy (CSCR) and single-nucleotide polymorphisms in the complement factor H (CFH) gene in patients of Chinese descent.
Methods: 437 CSCR patients and 510 controls were enrolled from the Department of Ophthalmology, People's Hospital of Peking University. We genotyped each patient for six single-nucleotide polymorphism (SNP) markers in CFH (rs800292, rs1061170, rs3753396, rs2284664, rs1329428, and rs1065489), and assessed each SNP's associations with CSCR. We also performed a meta-analysis of CFH SNPs associations with CSCR.
Results: In our Chinese population sample, two CFH SNPs—rs800292 and rs1065489—were significantly associated with CSCR. We found that rs800292 had the strongest association, and rs1065489 had the second strongest association. From a meta-analysis of all existing case-control studies on CFH SNPs and CSCR, we also found significant associations between CFH SNPs rs1329428, rs1065489, rs2284664, and rs800292, and CSCR.
Conclusions: Our results show a significant association between CSCR and two SNPs in the CFH gene, rs800292 and rs1065489, in a Chinese population. These findings suggest a role for CFH in CSCR pathogenesis. Further investigation into how CFH contributes to CSCR will improve our understanding of CSCR, and of CFH as a potential therapeutic target.
DEFORMATION FEATURES OF UNIAXIAL COMPRESSION OF SAMPLES FROM THE POTATO TUBERS FLESH
Authors: Zhukov V. G. , Lukin N. D. 
Published: July 2019

The article analyzes the deformation mechanism under uniaxial compression of cylindrical samples cut from the pulp of potato tuber. In its typical S-shaped stress-strain diagram, three characteristic zones of different types of dominant deformation can be distinguished. Clarified the boundary between the second and third zones. The rationale for changing the type of deformations in each zone by adding a new type to the previous one is presented. Grounded elastic deformation in the first zone, which is associated with stretching of the cell membranes. In the second zone, the destruction of individual cells distributed in the sample volume occurs and in the third zone — the predominant gradual unification of these destructions. An explanation is given of the characteristic brittle fracture of the sample with significant residual deformations at the end of the third zone. The erroneous determination of the deformations of the second and third zones as plastic (yield) was noted. In this regard, a new term was introduced — modulus of rigidity Z. The change in the modulus of stiffness Z with increasing irreversible deformations indicates structural changes in the flesh of the sample due to its gradually collapsing cell structure. The reason for straightening diagrams for samples from fresh, hard potato tubers is explained. Taking into account the type of deformations by zones allows us to reasonably proceed to the creation of criteria for quantitative assessments of the degree of flaccidity of potato tubers.
Alginate-based biotechnology: a review on the arsenic removal technologies and future possibilities
Authors: Chowdhury Shakhawat , Chowdhury Imran Rahman , Kabir Fayzul , Mazumder Mohammad Abu Jafar , Zahir Md. Hasan , Alhooshani Khalid 
Published: July 2019

Abstract
The alginate-based adsorption technologies have emerged as potential methods for arsenic removal from drinking water. The adsorbents (iron oxide, hydroxide, nano zero valent iron (nZVI), industrial waste, minerals, magnetite, goethite, zirconium oxide, etc.) are impregnated into alginate beads to produce the media. The biocompatibility, rough surface with large area, and amorphous and high water permeable bead structure improve arsenic adsorption efficiency while the regeneration process is simpler than the conventional adsorbents. In recent years, studies have reported laboratory-scale applications of alginate beads, encapsulated and impregnated with adsorbents, for arsenic removal from drinking water. The arsenic removal efficiencies were reported to be over 95% with a wide range of concentrations (10–1,000 parts per billion) and pH (3.0–7.5). However, commercial- and/or mass-scale applications have not been reported yet, due possibly to overall cost, complexity, reusability, and arsenic waste-laden sludge management. In this paper, research achievement on arsenic removal using alginate-based adsorbents has been reviewed. The review was performed in context to alginate bead development, adsorbent encapsulation and impregnation, application, performance, and regeneration. The advantages and limitations of the methods were analyzed and the scopes of future research were identified for mass scale domestic and industrial applications.
Determination of best groyne combination for mitigating bank erosion
Authors: Bora Kaushik , Kalita Hriday Mani 
Published: July 2019

Abstract
This paper presents a novel approach for determining the best combination of groynes in terms of their number, lengths and positions for controlling bank erosion. The vulnerable bank is considered to be protected if a very small value of water flow speed is achieved on the near bank area. A linked simulation–optimization model is developed in this regard which minimizes the total construction cost of the groyne project. At the same time, a constraint in terms of low flow speed in a predefined zone is incorporated, which helps in bank erosion prevention. In the simulation model, the depth-averaged shallow water equations are solved using a finite difference scheme. The optimization problem is formulated in three different approaches to tackle different types of in situ field problems. Genetic algorithm (GA) is used to solve the optimization problem. The proposed optimization model is used in two hypothetical test cases including one straight channel and one meandering channel. The results obtained with all the three formulations are found to be logical and establish the potential of the present model for application in real cases.
Effect of operating conditions on N2O production in an anammox sequencing batch reactor containing granular sludge
Authors: Pereira Tiago Duarte Santos , dos Santos Carla Eloísa Diniz , Lu Xi , Al-Hazmi Hussein E. , Majtacz Joanna , Pires Eduardo Cleto , Damianovic Márcia Helena Rissato Zamariolli , Makinia Jacek 
Published: July 2019

Abstract
Nitrous oxide (N2O) is one of the gases with the greatest impact in the atmosphere due to its persistence and significant contribution to the greenhouse effect. This study provides an insight into the dynamics of N2O production in wastewater nitrogen removal systems. A 10 L sequencing batch reactor containing enriched anammox biomass was subjected to different operational conditions, i.e., temperature, feed time, NO2−/NH4+ ratio and the initial concentrations of NH4+ and NO2−. Tests showed no significant differences in maximum N2O production when the system was operated with a shorter feed time and no increase in the operating temperature. A higher N2O production was observed when the initial NO2−/NH4+ ratio increased from 1.3 to 1.7 and 1.9. The highest initial concentration of NO2− was linked to an increase in residual N2O at the end of the batch cycle, probably due to heterotrophic denitrifying metabolism.
Resenha: A matemática nos anos iniciais do ensino fundamental – Tecendo fios do ensino fundamental
Authors: Souza Mônica Tavares de Oliveira 
Published: July 2019

Esta resenha tem como objetivo apresentar a obra “A Matemática nos anos iniciais do ensino fundamental – Tecendo fios do ensino fundamental” de Adair Mendes Nacarato, Brenda Leme da Silva Mengali e Cármen Lúcia Brancaglion Passos que discutem o ensino de Matemática nos anos iniciais do Ensino Fundamental num movimento indissociável entre o ensinar e o aprender.
Palavras Chaves: Ensino-aprendizagem; Matemática; Educação.
Erros e violações no preparo e administração de medicamentos na unidade de terapia intensiva
Authors: Cangussu Mauro Elisa Aparecida , Carreiro Mônica de Almeida 
Published: July 2019

Objetivo: Analisar a produção científica nacional sobre os erros na Administração de Medicamentos na Unidade de Tratamento Intensivo. Metodologia: Trata-se de uma revisão integrativa. A busca foi realizada nas bases de dados de saúde LILACS, Sciello, Mediline e BDENF, durante o mês de setembro de 2018, com os descritores Erros de Medicação, Segurança do Paciente, violação, UTI, administração de medicamentos, preparo de medicamentos, mediados pelo operador boleano “and” para ampliar a busca de estudos. Como critérios de inclusão foram utilizados estudos originais, dissertação e tese, de 2013 a 2017, na UTI. Foram excluídos do estudo editoriais, cartas ao editor, publicações repetidas e outras formas de publicações não disponíveis na internet, artigos que abordem outros aspectos de erros e violações não relacionados ao preparo e administração de medicamentos na UTI. Resultados: A amostra foi composta por 13 artigos. A análise dos dados identificou ocorrências de erros no ambiente, técnicas de preparo e administração de medicamentos. Conclusão: Poucos foram os estudos encontrados, porém enfatiza-se a necessidade de explorar mais a temática, considerando o seu impacto na qualidade da assistência e segurança do paciente.
Cuidados de Enfermagem para detecção de violência contra idosos
Authors: Azevedo Caterine Oliveira , Silva Thiago Augusto Soares Monteiro da 
Published: July 2019

Trata-se de um estudo exploratório de caráter descritivo com abordagem qualitativa realizado com 20 enfermeiros de um Hospital Universitário da Região Centro-Sul Fluminense do Estado do Rio de Janeiro. Foi utilizado um questionário semiestruturado com perguntas abertas e fechadas. A estratégia analítica usada para analisar os dados foi a análise de conteúdo. Os dados foram analisados e discutidos levando-se em consideração o conteúdo teórico apresentado na revisão de literatura. Constatou-se que os enfermeiros têm conhecimento abrangente sobre o conceito de violência, que ao identificarem situação de violência contra a pessoa idosa, eles se valem de diversas estratégias de proteção ao idoso e, consequentemente de enfrentamento da violência. Porém ficou evidente que diversos fatores intrínsecos ao idoso contribuem para dificultar a identificação da violência pelos enfermeiros, como medo, vergonha e omissão por medo do agressor ou por não querer denunciá-los por questões de afinidades parentais. Quanto ao reconhecimento dos sinais físicas evidentes, considera-se que este demanda muita cautela e conhecimento por parte dos enfermeiros para não confundir esses sinais com sinais decorrentes do próprio envelhecimento, com suposta violência. Diante da fragilidade da situação, o enfermeiro precisar ter além do conhecimento técnico-científico, sensibilidade para abordar adequadamente o idoso, de forma que consiga colher dele a maior quantidade possível de informações sobre a violência sofrida.
Manejo cirúrgico do paciente submetido à terapia anticoagulante oral
Authors: Da Silva Thaís Evellyn , Araújo Emanuele Castro de , Rocha Marcela Paschoal , Oliveira Leandro Moraes Coelho de 
Published: July 2019

Resumo
Introdução: Bem se sabe que quando um paciente está submetido à terapia anticoagulante, seus níveis de coagulação ficam alterados, aumentando o risco de intercorrências transoperatórias. Dessa forma, tem-se levantado muitos questionamentos, tanto na área médica como na odontológica, quanto à melhor conduta a se seguir para a realização de um tratamento cirúrgico-odontológico seguro em pacientes anticoagulados. Com o objetivo de realizar uma revisão de literatura abordando as peculiaridades inerentes ao atendimento adequado e com segurança desses pacientes, elucidando o método de diagnóstico, os exames pré-operatórios a serem solicitados, bem como os riscos existentes na manutenção ou interrupção da terapia anticoagulante a qual os pacientes estão sendo submetidos. Materiais e Métodos: Foi realizada uma busca na base de dados Scientific Electronic Library Online (SCIELO), PubMed e Google acadêmico com os descritores: “surgery oral”, “anticoagulants” e “toothextraction”, no mês de Setembro de 2018, onde foram levantados 25 artigos e foram selecionados 18 artigos de acordo com os critérios de inclusão. Conclusão: Foi observado que a manutençãodaterapêutica anticoagulante oral vem sendo preconizada, considerando o valor da Razão normalizada internacional (RNI) dentro do adequado como de sumaimportância, assim como o uso de alguma medida hemostática local, bem como as devidas instruções para o período de pós-operatório.
Descritores: Cirurgia bucal. Anticoagulantes. Extração dentária.
Estudo da adição de argila expandida e EPS como agregados na elaboração de concreto leve
Authors: Costa Maldonado Moncada Julio Ernesto , Flor Leonardo , Silva Viviane , Pacheco Jonas 
Published: July 2019

O presente trabalho apresenta uma análise comparativa entre o concreto convencional e o concreto leve com a substituição do agregado graúdo pela argila expandida e poliestireno expandido. Observa-se que o emprego destes elementos em materiais cimentícios viabiliza a redução do peso próprio de estruturas em concreto, assegurando uma minoração econômica no custo total da obra onde for aplicado o concreto leve. Para a realização deste estudo o fator água aglomerante atribuído ao concreto leve foi superior em relação ao traço elaborado para concreto convencional por possuir um agregado poroso. O projeto experimental realizou-se em laboratório à uma temperatura de 24,5°C e humidade relativa do ar de 71%Rh, obedecendo às normas regulamentadoras. O fator de eficiência obtido no concreto leve foi superior em todos os ensaios realizados, no entanto sua resistência mecânica à compressão apresentou um resultado inferior ao concreto convencional, porém ambos os concretos possuem função estrutural que estabelece como um valor mínimo a resistência de 20 MPa de acordo com a NBR 6118:2014. Contudo, observou-se que a adição de argila expandida e poliestireno expandido é viável, pois reduz a massa específica do concreto o que gera um alívio de carregamento nas estruturas reduzindo o custo global da construção. A segurança estrutural mantém-se garantida pelo fator eficiência.
Palavras chaves: concreto, agregado, eficiência
Phytochemical Profiles and Antibacterial Activities of Hydroalcoholic Extracts of Origanum vulgare and Hypericum perforatum and Carvacrol and Hypericin as a Promising Anti-Staphylococcus aureus
Authors: Bahmani Mahmoud , Taherikalani Morovat , Khaksarian Mojtaba , Soroush Setareh , Ashrafi Behnam , Heydari Rouhollah 
Published: July 2019

Objective:
Staphylococcus aureus, a Gram-positive bacteria, is ranked second among the
causes of hospital infections and is one of the three main causes of food poisoning. In recent times, the
spread of antibiotic resistance in S. aureus has become very worrisome. Therefore, research for new
effective drugs is important. The present study aims to investigate the phytochemical profiles and antibacterial
effects of hydroalcoholic extracts of Origanum vulgare (Lamiaceae family) and Hypericum
perforatum (Clusiaceae family) and their active compounds on S. aureus (ATCC 12600) in vitro.

Methods:
The identification of phytochemical compounds in both plants was performed by Highperformance
liquid chromatography (HPLC), headspace-solid-phase microextraction (HS-SPME) and
Fourier-transform infrared spectroscopy (FTIR). To investigate microbial susceptibility, minimum inhibitory
concentration (MIC), minimum bactericidal concentration (MBC) and disc diffusion method
(DAD) were used. Finally, the results of the study were compared with methicillin.

Results:
Of the 42 combinations of O. vulgare, carvacrol (48%) and of the 38 combinations of H. perforatum,
hypericin (46.2%) were the most abundant. The MIC, MBC and DAD of O. vulgare and H.
perforatum, carvacrol, hypericin and methicillin were 625, 625, 312.5, 78.12 and 384 µg/mL, 10000,
10000, 2500, 2500 and 384 µg/mL, and 15.66 ± 4.49, 12.66 ± 0.47 and 22 ± 0.81 mm, respectively.

Conclusion:
Due to the significant effects of O. vulgare and H. perforatum and their active components
against S. aureus, it is expected that in the future, hypericin, carvacrol and their derivatives can
be used as effective antibacterial agents against S. aureus.
The Pattern of Non-AIDS-defining Cancers in the HIV Population: Epidemiology, Risk Factors and Prognosis. A Review
Authors: Franzetti Marco , Ricci Elena , Bonfanti Paolo 
Published: July 2019

:
The advent of highly active antiretroviral therapy (HAART) has significantly reduced the
incidence of AIDS events, including AIDS-defining malignancies. Nevertheless, several cohort studies
conducted in the post-HAART period have reported an increasing risk of non-AIDS-defining
cancers (NADC).

:
Overall, the potential mechanisms leading to an increased risk of developing NADCs probably involve
multiple known and unknown factors. In addition to ageing, chronic inflammation and ongoing
immune system dysregulation, other contributing factors are co-infection with potentially oncogenic
viruses (HBV, HCV, HPV, EBV) and high-risk behaviours such as tobacco smoking.

:
As a consequence of these risk factors, high standardized incidence ratios have been consistently reported,
mainly in cohort studies regarding smoking-related cancers (lung cancer, but also pharyngeal
and kidney cancer), due to the far more common cigarette smoking habit in the HIV-population.
Also in the setting of infection-related malignancies, the high frequency of liver cancer, as a consequence
of HBV and HCV co-infection is well known. Similarly, HPV infection accounts for the
higher risk of anal cancer. On the same line, Hodgkin lymphoma is more frequent in the HIV population,
due to the dysregulation and proliferation of EBV-infected lymphocytes.

:
Several studies addressed the direct relationship between immunosuppression and cancer progression,
showing that subjects with HIV infection experience higher cancer-specific mortality, as compared
to the general population, independently of cancer stage or cancer treatment.

:
In the HIV population, for many NADCs, the prognosis is still worse as compared to the general
population. However, an improvement has been reported over the last decades, mainly thanks to
more available and adequate treatment chances.