bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonisothermal crystallization kinetics of PLA/nanosized YVO4 composites as a novel nucleating agent
Authors: El‐Taweel Safaa H. , Abboudi Mostafa 
Published: August 2019

ABSTRACTThe influence of nanosized YVO4 particles as a novel and efficient nucleating agent on the nonisothermal crystallization behaviors of poly(lactic acid) (PLA) was studied. A modified Avrami model was utilized to describe the nonisothermal crystallization kinetics of pure PLA and PLA nanocomposites. The differential isoconversional Friedmann formula was employed to calculate the effective activation energies (EX(t)) of nonisothermal crystallization from the glass state. The results showed that modified Avrami methods describe the nonisothermal crystallization kinetics of pure PLA and PLA nanocomposites well. The crystallization rate of PLA/1 mass% YVO4 was faster than that of pure PLA sample by factor 5 × 103 at a heating rate of 1 K min−1. While the values of Lauritzen–Hoffman parameters (Kg and U*) of the PLA/YVO4 nanocomposites were lower than those of pure PLA, indicating the nucleation efficiency of nanosized YVO4 particles for PLA. Scanning electron microscopy images reflect the uniform dispersion of 1 mass% YVO4 in PLA matrix. Thermogravimetric analysis results revealed that the thermal degradation parameters are slightly lowered by 7 °C on increasing the mass percentage of YVO4 in the PLA nanocomposites. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48340.
Failure mechanism of rigid polyurethane foam under high temperature vibration condition by experimental and finite element method
Authors: Wu Jiacheng , He Yannan , Yu Zhiqiang 
Published: August 2019

ABSTRACTThe failure mechanism of rigid polyurethane foam (RPUF) under room temperature (RT) and high temperature vibration conditions was investigated by experiment and finite element stimulation. Damaged RPUF specimens were prepared at different vibration amplitudes ranging from 0 to 19.879 mm at RT and 150 °C for different vibration times. The tensile test was utilized to evaluate the vibration damage degree of RPUFs, and the results exhibited that tensile strength decreased gradually with the increase of vibration amplitude and time at both RT and 150 °C. Thermogravimetric analysis and Fourier transform infrared spectroscopy illustrated that thermal degradation of RPUF is attributed to the decomposition of carbonyl urethane groups at 150 °C. The scanning electron microscopy analysis of the tensile fracture surfaces revealed that the vibration failure of RPUF mainly resulted from the existence of microcracks in cell structure. A finite element simulation was established by ABAQUS to study stress distribution of RPUF under different vibration loads, which then demonstrated that the microcracks are most likely to exist on the junction of two microcell units, which is due to convergence of stress in the process of vibration. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48343.
Functionalization of halloysite nanotubes with polyethyleneimine and various ionic liquid forms with antimicrobial activity
Authors: Suner Selin Sagbas , Sahiner Mehtap , Akcali Alper , Sahiner Nurettin 
Published: August 2019

ABSTRACTHalloysite nanotube (HNT), a natural clay, was modified with branched polyethyleneimine (PEI) to form PEI‐HNT using epichlorohydrin (ECH) as coupling agent, then protonated with HCl to obtain H‐PEI‐HNTs providing [NH3]+[Cl]− functionality for potential antimicrobial properties. Upon PEI modification, zeta potential value of HNTs was increased to +37.3 mV from −34.5 mV and to +41.1 mV for H‐PEI‐HNTs. Only 1.87 wt % H‐element in HNT was increased to 3.03 wt % upon PEI modification along with newly generated elements of N and C at 2.99 and 9.93 wt %, respectively. Moreover, ionic liquid (IL) forms of HNTs with [NH3]+[N(CN)2]−, [NH3]+[PF6]− and [NH3]+[BF4]− functionality were generated via anion exchange of H‐PEI‐HNTs with sodium dicyanamide (SDC), ammonium hexafluorophosphate (AHFP), and sodium tetrafluoroborate (STFB). The antimicrobial properties of the modified, protonated, and IL forms of HNTs were determined via macro dilution, diffusion and agar screening tests against Escherichia coli ATCC 8739, Pseudomonas aeruginosa ATCC 10145, Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 6538 strains, and Candida albicans ATCC 10231 strains. It was found that H‐PEI‐HNTs possesses potent antimicrobial effect compared with the other forms of HNTs with 2–4 mg mL−1 MIC and 8–16 mg mL−1 MBC values via the macro dilution method. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48352.
Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors
Authors: Schulert Grant S. , Yasin Shima , Carey Brenna , Chalk Claudia , Do Thuy , Schapiro Andrew H. , Husami Ammar , Watts Allen , Brunner Hermine I. , Huggins Jennifer , Mellins Elizabeth D. , Morgan Esi M. , Ting Tracy , Trapnell Bruce C. , Wikenheiser‐Brokamp Kathryn A. , Towe Christopher , Grom Alexei A. 
Published: August 2019

ObjectiveSystemic juvenile idiopathic arthritis (JIA) is associated with a recently recognized, albeit poorly defined and characterized, lung disease (LD). The objective of this study was to describe the clinical characteristics, risk factors, and histopathologic and immunologic features of this novel inflammatory LD associated with systemic JIA (designated SJIA‐LD).MethodsClinical data collected since 2010 were abstracted from the medical records of patients with systemic JIA from the Cincinnati Children's Hospital Medical Center. Epidemiologic, cellular, biochemical, genomic, and transcriptional profiling analyses were performed.ResultsEighteen patients with SJIA‐LD were identified. Radiographic findings included diffuse ground‐glass opacities, subpleural reticulation, interlobular septal thickening, and lymphadenopathy. Pathologic findings included patchy, but extensive, lymphoplasmacytic infiltrates and mixed features of pulmonary alveolar proteinosis (PAP) and endogenous lipoid pneumonia. Compared to systemic JIA patients without LD, those with SJIA‐LD were younger at the diagnosis of systemic JIA (odds ratio [OR] 6.5, P = 0.007), more often had prior episodes of macrophage activation syndrome (MAS) (OR 14.5, P < 0.001), had a greater frequency of adverse reactions to biologic therapy (OR 13.6, P < 0.001), and had higher serum levels of interleukin‐18 (IL‐18) (median 27,612 pg/ml versus 5,413 pg/ml; P = 0.047). Patients with SJIA‐LD lacked genetic, serologic, or functional evidence of granulocyte–macrophage colony‐stimulating factor pathway dysfunction, a feature that is typical of familial or autoimmune PAP. Moreover, bronchoalveolar lavage (BAL) fluid from patients with SJIA‐LD rarely demonstrated proteinaceous material and had less lipid‐laden macrophages than that seen in patients with primary PAP (mean 10.5% in patients with SJIA‐LD versus 66.1% in patients with primary PAP; P < 0.001). BAL fluid from patients with SJIA‐LD contained elevated levels of IL‐18 and the interferon‐γ–induced chemokines CXCL9 and CXCL10. Transcriptional profiling of the lung tissue from patients with SJIA‐LD identified up‐regulated type II interferon and T cell activation networks. This signature was also present in SJIA‐LD human lung tissue sections that lacked substantial histopathologic findings, suggesting that this activation signature may precede and drive the lung pathology in SJIA‐LD.ConclusionPulmonary disease is increasingly detected in children with systemic JIA, particularly in association with MAS. This entity has distinct clinical and immunologic features and represents an uncharacterized inflammatory LD.
Large‐Scale Screening and Design of Metal–Organic Frameworks for CH4/N2 Separation
Authors: Yan Tongan , Lan Youshi , Liu Dahuan , Yang Qingyuan , Zhong Chongli 
Published: August 2019

AbstractCH4/N2 separation is one of the great challenges in gas separation, which is of scientific and practical importance, such as in the upgrading of unconventional natural gas. Unfortunately, the separation performance is still quite low so far mainly due to their very close physical properties. In this work, a high‐throughput computational screening method was performed to develop metal–organic frameworks (MOFs) for efficient CH4/N2 separation. General designing rules as well as the correlation between selectivity and our proposed adsorbility (AD) parameter were obtained by carrying out systematic GCMC simulations of the existing 5109 CoRE MOFs. With the aid of this information, five virtual MOFs were screened out from the large database with 303 991 generated MOFs constructed in our previous work, exhibiting much higher selectivities than all the reported values. Among them, the selectivity of Zn‐PYZ‐BPY‐1 can reach over 29.0, about 2.4 times of the highest value reported in the literature. These results may not only suggest promising candidates for CH4/N2 separation but also provide useful information for large screening of MOFs for other specific separation mixtures.
Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Thymus
Authors: Li Xiao , He Ting , Wang Xiuhuan , Shen Meng , Yan Xin , Fan Shusheng , Wang Le , Wang Xiaoping , Xu Xiao , Sui Hong , She Gaimei 
Published: August 2019

AbstractThe genus Thymus (Lamiaceae) comprises about 214 species throughout the world, mainly found in North Africa, Europe, and temperate Asia zone. They are traditionally used as food additives and folk medicines. This review comprehensively summarizes information about traditional uses, chemical constituents, and biological activities of this genus and provides recommendations for future investigations. All information was gathered from scientific databases including Google Scholar, Sci‐Finder, Web of Science, ScienceDirect, and CNKI. Volatile oils are the most concerned constituents of this genus. Flavonoids, phenylpropanoids, tannins, organic acids, terpenoids, and phytosterols were also summarized. This genus plants possessed a variety of activities including antimicrobial, antioxidant, anti‐inflammatory, cytotoxic, analgesic, and antidiabetic. In brief, this review will be helpful to provide valuable data for explorations and create more interests towards Thymus genus in the future.
Aureonitols A and B, Two New C13‐Polyketides from Chaetomium globosum, an Endophytic Fungus in Salvia miltiorrhiza
Authors: Yang Sheng‐Xiang , Zhao Wen‐Ting , Chen Heng‐Ye , Zhang Lei , Liu Ting‐Kai , Chen He‐Ping , Yang Jian , Yang Xiao‐Long 
Published: August 2019

AbstractTwo new C13‐polyketides, aureonitols A and B (1 and 2), along with five known compounds (3–7), were isolated from the solid fermentation culture of the plant endophytic fungus Chaetomium globosum from the aerial parts of Salvia miltiorrhiza. The structures and absolute configurations of 1 and 2 were determined by comprehensive spectroscopic data analysis and computed methods. Compound 5 was found to display the remarkable antimicrobial activities against four multidrug‐resistant bacteria (Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, and Staphylococcus epidermidis) with MIC values of 3.13–6.25 μg/mL (ciprofloxacin: 0.78–1.56 μg/mL), and also against all tested fungal strains with MIC values of 3.13–25 μg/mL (ketoconazole: 0.78–12.50 μg/mL).
Sprouting of oats: A new approach to quantify compositional changes
Authors: Krapf Julia , Kandzia Franziska , Brühan Juliane , Walther Goeran , Flöter Eckhard 
Published: August 2019

AbstractBackground and objectivesThe aim of this research was to gain a deeper insight into the effect caused by the addition of sprouted oat to food products. The effect of temperature and duration of the sprouting process was systematically studied by sprouting oat grains between 10 and 30°C for up to 3 days.FindingsOverall, it was found that temperatures between 20 and 25°C yield the most dramatic changes in the properties of sprouted oats. Based on the data, a simple system to characterize the sprouting progress by a visual inspection of the lengths of the coleoptile and radicles was developed. This degree of sprouting (DoS) was correlated with further grain properties.ConclusionsIt was found that an exponential relationship between the DoS and grain properties existed. Furthermore, the observed increase in the reducing sugar content (up to 14.6 g/100 g) with increasing DoS was closely related to the increase in α‐amylase activity (up to 25 U/g).Significance and noveltyThe good predictive power found indicates that the application of the concept degree of sprouting could develop into a reliable characterization method for sprouted grains usable for product development and specification.
A case of recalcitrant acute generalized exanthematous pustulosis with Sjogren's syndrome: Successfully treated with low‐dose cyclosporine
Authors: İslamoğlu Zeynep Gizem Kaya , Karabağli Pınar 
Published: August 2019

AbstractAcute generalized exanthematous pustulosis (AGEP) is a reaction attributed mainly to drugs. Hydroxychloroquine is a rare cause of AGEP especially used in rheumatology and dermatology. Systemic corticosteroids are the first‐line treatment agents in AGEP. But cyclosporine can be a good choice for patients resistant to systemic corticosteroid treatment in AGEP.
Three‐Dimensional Porous TiNb2O7/CNT‐KB Composite Microspheres as Lithium‐Ion Battery Anode Material
Authors: Liu Min , Dong Houcai , Zhang Shuo , Chen Xi , Sun Yiping , Gao Shan , Xu Jiaqiang , Wu Xiaodong , Yuan Anbao , Lu Wei 
Published: August 2019

AbstractNano‐TiNb2O7/multiwalled carbon nanotube and ketjen black (TiNb2O7/CNT‐KB) composite microspheres with porous three‐dimensional (3D) hierarchical heterostructure are fabricated by spray drying and solvothermal method. This composite material exhibits a high reversible charge specific capacity of 327.8 mAh g−1 at the current rate of 0.1 C and 151.1 mAh g−1 at 20 C rate. When it is cycled at a high current rate of 5 C for 1000 cycles, the charge capacity is dropped from the maximum value of 220.8 mAh g−1 (6th cycle) to the end value of 145.4 mAh g−1, with capacity retention of 65.9 %. The TiNb2O7/CNT‐KB composite material demonstrates much superior electrochemical performance over the bare TiNb2O7 material, and this result should be attributed to its particular porous 3D hierarchical structure, which possesses enhanced electrical conductivity as well as the ability for accommodating volume change and preventing particle aggregation of the electrode active material during the discharge and charge cycles.
Static and dynamic behavior of cellular glass products used for the bottom insulation of flat bottom tanks
Authors: Waas Till , Hertle Robert , Krol Marian 
Published: August 2019

AbstractThis paper gives a general introduction to the design of load bearing insulation systems made from cellular glass for flat bottom tanks used to store cryogenic liquids. The mechanical properties of cellular glass are summarized and the current situation of the set of rules and regulations regarding design and construction of bottom insulation systems is presented. The intention of this paper is to bring attention to the dynamic behavior of cellular glass bottom insulation systems under horizontal earthquake acceleration. Within this paper, the basic results of cyclic shear force tests performed on cellular glass blocks are presented. The intention of these tests was to determine the dynamic behavior of a bottom insulation system exposed to shear inducing seismic actions. A procedure for implementing the dynamic properties of cellular glass into a multi modal dynamic model is presented and verified by a dynamic calculation.
C−H and C−M Activation, Aromaticity Tuning, and Co⋅⋅⋅Ru Interactions Confined in the Azuliporphyrin Framework
Authors: Białek Michał J. , Chmielewski Piotr J. , Latos‐Grażyński Lechosław 
Published: August 2019

AbstractTaking advantage of the specific properties of azuliporphyrin and the reactivity of cobalt(II), activation of an azulene C(sp2)−H bond occurred and organometallic complexes with Co−C bonding were formed. The system allowed for macrocyclic aromaticity tuning through metal coordination and oxidation. Thanks to the CoII−C and parallel tested CuII−C reactivity and the affinity of metal centers to dioxygen, oxygen atom insertion into the M−C bond could be investigated. Insertion starts with an oxygen molecule coordination and leads to monomeric and dimeric complexes of specific electronic structures. Formation of unique paramagnetic σ/π‐hybrid bimetallic complexes enabled spectroscopic and theoretical investigations of peculiar CoII⋅⋅⋅Ru0 interactions.
Chirality‐Controlled Self‐Assembly of Amphiphilic Dibenzo[6]helicenes into Langmuir–Blodgett Thin Films
Authors: Holec Jan , Rybáček Jiří , Vacek Jaroslav , Karras Manfred , Bednárová Lucie , Buděšínský Miloš , Slušná Michaela , Holý Petr , Schmidt Bernd , Stará Irena G. , Starý Ivo 
Published: August 2019

AbstractInvited for the cover of this issue is Bernd Schmidt and co‐workers at University of Potsdam and Irena G. Stará, Ivo Starý and co‐workers at IOCB Prague. The image depicts two assemblies of an amphiphilic helicene molecule that float on the water surface and differ in chirality: The racemic “raft” is more stable than the enantiopure one. Read the full text of the article at 10.1002/chem.201901695.
Two cases of eczematous eruptions caused by everolimus
Authors: Habu Minako , Tohyama Mikiko , Sayama Koji 
Published: August 2019

AbstractObjectiveEverolimus, an inhibitor of the mammalian target of rapamycin, has been used in the treatment of several types of tumor. Erythematous maculopapular and acneiform rashes are the major dermatological adverse events associated with everolimus therapy, but we encountered two cases of eczematous eruption caused by everolimus.MethodWe assessed the clinical features and laboratory findings of the two cases.ResultsA 52‐year‐old woman and a 59‐year‐old man developed pruritic papules and erythema over their entire bodies after initiation of everolimus therapy. Both patients exhibited peripheral eosinophilia and increased serum thymus and activation‐regulated chemokine (TARC) levels. A skin biopsy from one patient revealed the features of chronic dermatitis. Both the skin manifestations and the pruritis disappeared rapidly after the discontinuation of everolimus treatment. The peripheral blood eosinophil and serum TARC levels also decreased.ConclusionEczematous eruption associated with an elevated serum TARC level is a dermatological event associated with everolimus therapy.
Modelling coke formation in an industrial ethane‐cracking furnace for ethylene production
Authors: Karimi Hadiseh , Olayiwola Bolaji , Farag Hany , McAuley Kimberley B. 
Published: August 2019

AbstractThe development of a model for predicting coke formation in an industrial ethylene cracking furnace is described. Expressions for predicting the rates of catalytic and pyrolytic coke formation are developed and a differential equation is derived to predict changes in coke thickness with time and position. An expression is developed to account for a decline in the rate of catalytic coke formation with increasing thickness of the coke layer. The proposed coke model equations are used to extend a previously developed ethane pyrolysis furnace model that ignored coke. Three model parameters related to coke formation are estimated using industrial data to obtain reliable model predictions. Two of these parameters are coefficients that appear in the catalytic and pyrolytic coke formation rate expressions. The third is a characteristic‐length parameter used to reduce the rate of catalytic coke formation as the coke layer grows. The resulting dynamic model matches the industrial data well and can be used to simulate furnace operation and predict coke thickness profiles over a variety of the operating conditions, thereby helping process engineers who plan the decoking process.
Underutilization of guideline‐recommended supportive care among older adults with multiple myeloma in the United States
Authors: Giri Smith , Zhu Weiwei , Wang Rong , Zeidan Amer , Podoltsev Nikolai , Gore Steven D. , Neparidze Natalia , Ma Xiaomei , Gross Cary P. , Davidoff Amy J. , Huntington Scott F. 
Published: August 2019

BackgroundWith improving survival for patients with multiple myeloma (MM), supportive care that is focused on optimizing quality of life and minimizing treatment‐related toxicities is increasingly important. The extent to which patients with MM are receiving recommended supportive care is unknown.MethodsThis study used the Surveillance, Epidemiology, and End Results–Medicare database to identify older adults (age ≥66 years) diagnosed with MM in 2008‐2013 who had received active treatment and survived 1 year or longer after their diagnosis. Outcomes of interest included guideline‐recommended supportive care, which was defined as 1) bone‐modifying drugs (BMDs) within the 12 months after the diagnosis, 2) influenza vaccination in the first season after the diagnosis, and 3) concomitant use of prophylactic antivirals with proteasome inhibitors. Multivariable logistic regression models were used to evaluate associations between patient/facility‐level characteristics and supportive care use.ResultsAmong 1996 patients receiving MM‐directed therapy, 64%, 52%, and 49% received BMDs, an influenza vaccination, and antiviral prophylaxis, respectively. Non‐Hispanic black patients (odds ratio [OR] vs white patients, 0.63; 95% confidence interval [CI], 0.46‐0.88) and patients with baseline renal impairment (OR, 0.43; 95% CI, 0.34‐0.54) had lower odds of BMDs. Non‐Hispanic blacks (OR, 0.52; 95% CI, 0.37‐0.73) and those with dual Medicaid enrollment (OR, 0.76; 95% CI, 0.58‐0.99) had lower odds of influenza vaccination. Treatment in a community‐based setting was associated with reduced odds of antiviral prophylaxis (OR, 0.58; 95% CI, 0.46‐0.72).ConclusionsSubstantial underutilization of guideline‐recommended supportive care was observed among older adults with MM in the United States, and this was associated with both patient and facility characteristics. Targeted interventions are needed to improve supportive care for patients with MM.
Global Bifurcation of Rotating Vortex Patches
Authors: Hassainia Zineb , Masmoudi Nader , Wheeler Miles H. 
Published: August 2019

AbstractWe rigorously construct continuous curves of rotating vortex patch solutions to the two‐dimensional Euler equations. The curves are large in that, as the parameter tends to infinity, the minimum along the interface of the angular fluid velocity in the rotating frame becomes arbitrarily small. This is consistent with the conjectured existence [30, 38] of singular limiting patches with 90 corners at which the relative fluid velocity vanishes. For solutions close to the disk, we prove that there are “cat's‐eyes”‐type structures in the flow, and provide numerical evidence that these structures persist along the entire solution curves and are related to the formation of corners. We also show, for any rotating vortex patch, that the boundary is analytic as soon as it is sufficiently regular. © 2019 Wiley Periodicals, Inc.