bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Update on Core Jasmonate Signalling Networks, Physiological Scenarios, and Health Applications
Authors: Pérez‐Salamó Imma , Krasauskas Jovaras , Gates Shannah , Díaz‐Sánchez Eva K. , Devoto Alessandra 
Published: May 2019

AbstractJasmonic acid, its precursors in the biosynthetic pathway and derivatives are lipid‐derived signalling molecules. Together with other plant hormones, they regulate responses to stress (biotic and abiotic), mediate defence (against pathogens and herbivores), and a plethora of processes including growth and reproductive development in different plant species.The discovery of jasmonates is more recent than that of auxin, abscisic acid, cytokinins, gibberellic acid, ethylene, and salicylic acid; however, their role in regulating plant developmental plasticity is second to none. Since the 1990s, research made substantial advances and added to the crosstalk with the abovementioned other hormones and signalling pathways. Building on the knowledge of over two decades, an update on the research in JAs signalling components regulating plant responses to developmental and environmental cues is provided here. Information inArabidopsis thalianais integrated with reports on other plants. Recent findings in the regulation of plant responses to biotics and abiotic stressors and evidence implicating JAs in the regulation of the trade‐off between growth and stress will be reported. Health applications for JAs and JAs‐induced secondary metabolism, bridging the gap between biotechnology and traditional medicine, will illustrate the practical and societal relevance of investigating the functions of such compounds.
Plant Pangenome: Impacts on Phenotypes and Evolution
Authors: Tranchant‐Dubreuil Christine , Rouard Mathieu , Sabot Francois 
Published: May 2019

AbstractWith the emergence of low‐cost high‐throughput sequencing technologies, numerous studies have shown that a single genome is not enough to identify all the genes present in a species. Recently, the pangenome concept has become widely used to investigate genome composition of a collection of individuals. The pangenome consists in the core genome, which encompasses all the sequences shared by all the individuals, and the dispensable genome, composed of sequences present in only some individuals. Pangenomic analyses open new ways to investigate and compare multiple genomes of closely related individuals at once, and more broadly new opportunities for optimising breeding and studying evolution. This emerging concept combined with the power of the third‐generation sequencing technologies gives unprecedented opportunities to uncover new genes, to fully explore genetic diversity and to advance knowledge about the evolutionary forces that shape genome organisation and dynamics.
Phytobiomes, the Reason Why Microbiologists and Botanists Should Work Together
Authors: Snoeijenbos Michelle , Cárdenas Martha , Guevara‐Suarez Marcela , Bernal Adriana , Jiménez Pedro , Restrepo Silvia 
Published: May 2019

Abstract
Phytobiomes consist of plants, their environment, and their associated communities of macro and microorganisms. Within the phytobiome, the microbiome consists of the microorganisms associated with the plants comprising the endophytes and epiphytes. Endophytes are microorganisms, mainly consisting of bacteria and fungi, which colonise internal plant tissues without causing any disease symptom or tissue damage in different hosts. All these organisms associated to the plant contribute to its fitness. In this article, we revised a total of 103 studies containing the terms phytobiomes and microbiomes and endophytes, with the aims of reviewing: (i) the evolution of the term endophyte and the evolution of the endophyte condition; (ii) the current literature on studies considering the endophyte community within phytobiomes; and (iii) the literature on the bacteria living in fungal endophytes. In our analyses, we highlighted the biases that have been introduced in the phytobiomes' studies. For example, the presence of endohyphal bacteria could have contributed to overestimating the number of bacterial endophytes in the scientific literature. This is the first article that includes studies that evaluate endophytes that are not considered alone but belonging to a complex interacting community, the phytobiome.
Targeted Exfoliation and Reassembly of Polymeric Carbon Nitride for Efficient Photocatalysis
Authors: Li Yunxiang , Ouyang Shuxin , Xu Hua , Hou Weishu , Zhao Ming , Chen Huayu , Ye Jinhua 
Published: May 2019

AbstractSwitching the properties of photocatalytic materials targetedly and exerting these advantages fully in different photoredox reactions are crucial for the sufficient utilization of solar energy but still presents a significant challenge. This study presents a facile, green, and reversible exfoliation–reassembly strategy to switch the features of polymeric carbon nitride (CN) favorably for different photoredox reactions. The giant expansion effect of in situ‐generated H2O molecules confined to the interlayer results in the mass production of ultrathin polymeric CN nanosheets, giving a high yield, i.e., up to 48%, of ultrathin nanosheets in a mild solution (pH ≈1.3). Interestingly, the exfoliation–reassembly process as well as the properties of CN are largely reversible via alternating the interlayer groups. Moreover, the exfoliated and reassembled CN achieve a superior photocatalytic activity for isopropanol degradation (acetone: 345 µmol h−1; CO2: 23 µmol h−1) and H2 evolution (1370 µmol h−1), resulting in a high apparent quantum yield of 27% and 46%, respectively, at ≈420 nm.
Restricting Lattice Flexibility in Polycrystalline Metal–Organic Framework Membranes for Carbon Capture
Authors: Babu Deepu J. , He Guangwei , Hao Jian , Vahdat Mohammad Tohidi , Schouwink Pascal Alexander , Mensi Mounir , Agrawal Kumar Varoon 
Published: May 2019

AbstractAlthough polycrystalline metal‐organic framework (MOF) membranes offer several advantages over other nanoporous membranes, thus far they have not yielded good CO2 separation performance, crucial for energy‐efficient carbon capture. ZIF‐8, one of the most popular MOFs, has a crystallographically determined pore aperture of 0.34 nm, ideal for CO2/N2 and CO2/CH4 separation; however, its flexible lattice restricts the corresponding separation selectivities to below 5. A novel postsynthetic rapid heat treatment (RHT), implemented in a few seconds at 360 °C, which drastically improves the carbon capture performance of the ZIF‐8 membranes, is reported. Lattice stiffening is confirmed by the appearance of a temperature‐activated transport, attributed to a stronger interaction of gas molecules with the pore aperture, with activation energy increasing with the molecular size (CH4 > CO2 > H2). Unprecedented CO2/CH4, CO2/N2, and H2/CH4 selectivities exceeding 30, 30, and 175, respectively, and complete blockage of C3H6, are achieved. Spectroscopic and X‐ray diffraction studies confirm that while the coordination environment and crystallinity are unaffected, lattice distortion and strain are incorporated in the ZIF‐8 lattice, increasing the lattice stiffness. Overall, RHT treatment is a facile and versatile technique that can vastly improve the gas‐separation performance of the MOF membranes.
Modular and Reconfigurable Wireless E‐Tattoos for Personalized Sensing
Authors: Jeong Hyoyoung , Wang Liu , Ha Taewoo , Mitbander Ruchika , Yang Xiangxing , Dai Zhaohe , Qiao Shutao , Shen Linxiao , Sun Nan , Lu Nanshu 
Published: May 2019

AbstractIn the past few years, ultrathin and ultrasoft epidermal electronics (a.k.a. e‐tattoos) emerged as the next‐generation wearables for telemedicine, mobile health, performance tracking, human‐machine interface (HMI), and so on. However, it is not possible to build an all‐purpose e‐tattoo that can accommodate such a wide range of applications. Thus, the design, fabrication, and validation of modular and reconfigurable wireless e‐tattoos for personalized sensing are reported. Such e‐tattoos feature a multilayer stack of stretchable layers of distinct functionalities—a near field communication (NFC) layer capable of wireless power harvesting and data transmission, a functional circuit layer, and a passive electrode/sensor layer. These layers can be disassembled and swapped out multiple times to form different e‐tattoos of different sensing capabilities. Such modular and wireless e‐tattoos can be rapid‐prototyped via a dry, digital, and cost‐effective fabrication process—the “cut‐solder‐paste” process. They have been successfully applied to wirelessly measure a variety of biometrics.
In Situ Fine‐Tuning of Microfluidic Chips by Swelling and Its Application to Droplet Microfluidics
Authors: González‐Estefan Juan H. , Gonidec Mathieu , Vu Thi Thiet , Daro Nathalie , Chastanet Guillaume 
Published: May 2019

AbstractOver the last two decades, polydimethylsiloxane (PDMS) has been widely used as the material of choice for fast‐throughput prototyping of microfluidic devices due to the ease of fabrication of PDMS devices by soft‐lithography replica molding methods. Nevertheless, PDMS is known to swell significantly in a variety of organic solvents which has sometimes limited its use in synthetic chemistry and has led the microfluidic community to consider PDMS as being “incompatible” with such solvents. Nevertheless, as shown here, when analyzed deeper and controlled properly, the solvent‐induced swelling of PDMS actually constitutes a potentially useful phenomenon that can become a simple tool to control and adjust finely and dynamically the geometry of microfluidic chips in situ. In this paper, this method is applied to the control of the behavior of a variety of droplet generators. The simplicity and efficiency of this approach make it a great asset for droplet microfluidics synthesis, for which microreactor sizes are a critical parameter that is often overlooked due to its complex implementation. In a more general sense, it is expected that integrating swelling into design should allow to adjust the function of many different types of chips exhibiting geometry‐driven functions.
Optimized‐Surface Wettability: A New Experimental 3D Modeling Approach Predicting Favorable Biomaterial–Cell Interactions
Authors: do Nascimento Rodney Marcelo , Sarig Udi , da Cruz Nilson Cristino , de Carvalho Vanessa Rafaela , Eyssartier Camille , Siad Larbi , Ganghoffer Jean‐François , Hernandes Antônio Carlos , Rahouadj Rachid 
Published: May 2019

AbstractDespite several decades of research on biomedical implant materials, the identification of predictive and robust in vitro characteristics of cell support ability and viabilities—as indicators of biocompatibility and future implant‐tissue integration—remain elusive. This study addresses the phenomenology of cell–implant interfaces based on experimental, theoretical, and numerical analysis of cell response to functionalized bioceramic coatings of commercial titanium implants, cp‐Ti. A variable spectrum of coatings having differing surface wettabilities, with optimized solid tension values, is obtained. Measured values are modeled and correlated to cell support ability and viabilities. The contributions of different surface aspects to cell viability are decoupled, resulting in the identification of the polar component of the surface free energy as a significant and major cell–substrate effector. Furthermore, results of this study and the suggested model establish the thermodynamic interfacial free energy as an omnipotent measure that can be fully correlated to the morphology of an individual cell under numerical simulation matching empirical observations. Collectively, the 3D model reported herein can offer a new generic theoretical framework, using implementable mathematical simulation, toward the objective of rational biomaterial design that can improve next‐generation metal and ceramic implants.
Polyelemental, Multicomponent Perovskite Semiconductor Libraries through Combinatorial Screening
Authors: Saliba Michael 
Published: May 2019

AbstractRecently, perovskites with multiple cations, metals, and anions have shown very high efficiencies and stabilities for perovskite solar cells. The novel materials frequently exhibit unexpected and beneficial properties, outperforming simpler counterparts. The trend of increasing material complexity requires a systematic strategy to explore polyelemental “multicomponent engineering.” Here, a combinatorial approach is introduced to generate all possible, unique combinations within a set of available components. Thus, with each new component, the combinatorial framework can generate the full theoretical parameter space. Based on reported components, the experimental parameter space can then be identified. The exceptional material versatility of perovskites is suited for high‐throughput screening, machine‐learning, or data mining, laying the foundation for a “perovskite genome project” that thoroughly catalogues the entire material family for desired properties. This can provide the framework for theoretical simulations toward understanding the fundamental working principles of perovskite materials enabling the “next big thing” after perovskites. Finally, informed by literature, a promising candidate list for future material exploration is presented including novel organic‐free, Pb‐free, and all‐inorganic perovskites. These compounds are primary contenders toward stable, high efficiency, and reproducible materials for rapid industrialization of perovskite solar cells, lasers, light‐emitting diodes, photo detectors, or particle detectors.
A Green and Sustainable Approach for Selective Halogenation of Anilides, Benzanilides, Sulphonamides and Heterocycles†
Authors: Lakshmireddy V. M. , Naga Veera Y. , Reddy T. J. , Rao V. J. , China Raju B. 
Published: May 2019

AbstractAn efficient green and sustainable protocol has been devised for the selective oxidative halogenation of acetanilides, benzanilides, sulphonamides, and heterocyclic compounds, using easily available NaX as a halogen source and Oxone as a powerful oxidant. Reaction products were analyzed by GC‐MS. Defined experimental conditions provided the mono and dihalo compounds. The present protocol is simple and environmentally benign to conduct the laboratory scale halogenations and can be extended to prepare industrially important compounds.
Individual acquisition of “stick pounding” behavior by naïve chimpanzees
Authors: Bandini Elisa , Tennie Claudio 
Published: May 2019

AbstractMany studies investigating culture in nonhuman animals tend to focus on the inferred need of social learning mechanisms that transmit the form of a behavior to explain the population differences observed in wild animal behavioral repertoires. This research focus often results in studies overlooking the possibility of individuals being able to develop behavioral forms without requiring social learning. The disregard of individual learning abilities is most clearly observed in the nonhuman great ape literature, where there is a persistent claim that chimpanzee behaviors, in particular, require various forms of social learning mechanisms. These special social learning abilities have been argued to explain the acquisition of the relatively large behavioral repertoires observed across chimpanzee populations. However, current evidence suggests that although low‐fidelity social learning plays a role in harmonizing and stabilizing the frequency of behaviors within chimpanzee populations, some (if not all) of the forms that chimpanzee behaviors take may develop independently of social learning. If so, they would be latent solutions—behavioral forms that can (re‐)emerge even in the absence of observational opportunities, via individual (re)innovations. Through a combination of individual and low‐fidelity social learning, the population‐wide patterns of behaviors observed in great ape species are then established and stably maintained. This is the Zone of Latent Solutions (ZLS) hypothesis. The current study experimentally tested the ZLS hypothesis for pestle pounding, a wild chimpanzee behavior. We tested the reinnovation of this behavior in semi‐wild chimpanzees at Chimfunshi Wildlife Orphanage in Zambia, Africa, (N = 90, tested in four social groups). Crucially, all subjects were naïve to stick pounding before testing. Three out of the four tested groups reinnovated stick pounding—clearly demonstrating that this behavioral form does not require social learning. These findings provide support for the ZLS hypothesis alongside further evidence for the individual learning abilities of chimpanzees.
Nasal saline irrigation: a clinical update
Authors: Succar Eric F. , Turner Justin H. , Chandra Rakesh K. 
Published: May 2019

BackgroundNasal saline irrigation (NSI) plays an important role in the treatment of chronic rhinosinusitis (CRS). It is a beneficial low‐risk treatment that serves an adjunctive function in the medical and surgical management of CRS. NSI is hypothesized to function by thinning mucous, improving mucociliary clearance, decreasing edema, and reducing antigen load in the nasal and sinus cavities. Although its use in CRS is nearly universal, significant variety exists with regard to delivery volume, delivery pressure, frequency of use, duration of use, composition, and hygiene recommendations. Evidence is limited regarding the most optimal methods of NSI delivery. In addition, use of NSI has recently come under increasing scrutiny due to potential associations with cases of primary amebic meningoencephalitis.MethodsIn this review we provide a clinical update summarizing use of NSI for treatment of CRS, including current recommendations for use, and data regarding overall efficacy, available delivery devices, solution composition, and hygiene.ResultsCurrent evidence and recommendations for nasal saline delivery methods, composition, and hygiene are presented.ConclusionThe most recent consensus statements and Cochrane Review recommend the use of NSI for CRS based on a preponderance of lower level evidence. A conclusion regarding the optimal method of delivery and solution composition cannot be drawn based on the current literature.
Topical antibiotic therapy in chronic rhinosinusitis: an update
Authors: Carlton Daniel A. , Beahm D. David , Chiu Alexander G. 
Published: May 2019

BackgroundTopical antibiotic therapies have been investigated for their use in chronic rhinosinusitis (CRS). However, society guidelines and evidence‐based medicine reviews have recommended against the use of topical antibiotic therapy based on randomized controlled trials (RCTs). The purpose of this article is to review recent clinical research published since the aforementioned guidelines were published.MethodsA structured literature review was performed on clinical studies published in the last 5 years investigating the use of topical antibiotic therapies.ResultsOne double‐blinded, randomized controlled trial (DB‐RCT) supported the use of tobramycin using a vibrating aerosolizer; 1 non‐blinded non‐randomized controlled prospective trial lent support to use of topical ofloxacin for its anti‐biofilm properties; and 1 meta‐analysis found mupirocin irrigations to be beneficial in the short term. One Cochrane Review was unable to make a recommendation as no trial met the inclusion criteria. An additional systematic review found limited evidence to support the use of topical antibiotics with the exception of mupirocin irrigations that may be considered in Staphylococcus aureus infections. Two retrospective studies found that topical antibiotics change bacterial cultures of the sinuses.ConclusionThere is additional evidence to support continuing investigation of topical antibiotic therapies. Further, larger RCTs are required to establish the efficacy of topical antibiotic therapies.
Sulfur‐Based Electrodes that Function via Multielectron Reactions for Room‐Temperature Sodium‐Ion Storage
Authors: Wang Yun‐Xiao , Lai Wei‐Hong , Wang Yun‐Xia , Chou Shu‐Lei , Ai Xinping , Yang Hanxi , Cao Yuliang 
Published: May 2019

AbstractEmerging rechargeable sodium‐ion storage systems—sodium‐ion and room‐temperature sodium–sulfur (RT‐NaS) batteries—are gaining extensive research interest as low‐cost options for large‐scale energy‐storage applications. Owing to their abundance, easy accessibility, and unique physical and chemical properties, sulfur‐based materials, in particular metal sulfides (MSx) and elemental sulfur (S), are currently regarded as promising electrode candidates for Na‐storage technologies with high capacity and excellent redox reversibility based on multielectron conversion reactions. Here, we present current understanding of Na‐storage mechanisms of the S‐based electrode materials. Recent progress and strategies for improving electronic conductivity and tolerating volume variations of the MSx anodes in Na‐ion batteries are reviewed. In addition, current advances on S cathodes in RT‐NaS batteries are presented. We outline a novel emerging concept of integrating MSx electrocatalysts into conventional carbonaceous matrices as effective polarized S hosts in RT‐NaS batteries as well. This comprehensive progress report could provide guidance for research toward the development of S‐based materials for the future Na‐storage techniques.
miR‐455‐5p Overexpression Reduces Rat Lung Alveolar Type II Cell Proliferation by Downregulating STRA6
Authors: Zheng Jintao , He Qiuming , Tang Huajian , Xia Huimin 
Published: May 2019

ABSTRACTmiR‐455‐5p and retinoid signaling pathway and its membrane receptor, STRA6, are associated with lung development. Software copredictions indicate that the miRNA upstream of the STRA6 gene is miR‐455‐5p. We hypothesized that miR‐455‐5p participates in rat lung alveolar Type II cell proliferation by targeting STRA6 and designed this study to investigate the effects of miR‐455‐5p overexpression on rat lung alveolar Type II cells. Dual luciferase reporter gene assay was utilized to confirm the relationship between miR‐455‐5p and STRA6. An miR‐455‐5p‐expressing adenoviral vector was constructed and transfected into rat lung alveolar Type II cells. STRA6 protein expression was detected in rat lung alveolar Type II cells by Western blotting at 72 hr posttransfection. Retinol concentration was detected by ELISA at 72 hr posttransfection. The cell proliferation was detected by CCK8 assay at 24, 48, and 72 hr posttransfection. Our results showed that STRA6 is a target gene of miR‐455‐5p. STRA6 protein expression was significantly lower in the miR‐455‐5p‐overexpression group than in the NC group (0.615 ± 0.131 vs. 0.958 ± 0.246, P = 0.029). Similar results were observed for retinol concentration (2.985 ± 0.061 vs. 3.949 ± 0.118, P = 0.000). Rat lung alveolar Type II cell proliferation was lower in the miR‐455‐5p‐overexpression group than in the NC group at 24, 48, and 72 hr posttransfection (24 hr: 0.280 ± 0.184 vs. 1.354 ± 0.169 P = 0.026; 48 hr: 0.881 ± 0.016 vs. 1.992 ± 0.050 P = 0.001; 72 hr: 2.105 ± 0.148 vs. 2.937 ± 0.079 P = 0.016). In summary, miR‐455‐5p is associated with lung development. miR‐455‐5p overexpression downregulates STRA6, leading to reduced retinol concentration and rat lung alveolar Type II cell proliferation. Anat Rec, 302:2062–2069, 2019. © 2019 The Authors. The Anatomical Record published by Wiley Periodicals, Inc. on behalf of American Association of Anatomists.