bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS PENGARUH THE BIG FIVE PERSONALITY TERHADAP KINERJA PERAWAT MELALUI ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB) SEBAGAI VARIABEL MEDIASI
Authors: Pahriani Rika , Pratiwi Reski Dewi , Nuryadin Aftiyana Ameliya 
Published: November 2024

Kinerja tenaga keperawatan masih menjadi perhatian utamanya di negara-negara berkembang seperti Indonesia, Philipina, Thailand dan Malaysia. Namun pada kenyataanya kinerja perawat di Indonesia masih cukup memprihatinkan dibandingkan dengan negara-negara ASEAN lainnya. Terjadinya penurunan kinerja perawat saat ini, berdampak pada rendahnya pelayanan kesehatan yang diterima masyarakat. Sehingga sebagian rumah sakit mengalami penurunan tingkat kunjungan pasien yang berdampak pada buruknya produktivitas rumah sakit. Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh the big five personality terhadap kinerja perawat melalui OCB sebagai variabel mediasi di Rumah Sakit TK. II 14.05.01 Pelamonia Makassar. Jenis penelitian ini yaitu kuantitatif dengan menggunakan pendekatan cross sectional study. Penelitian ini dilakukan di ruang rawat inap dan ruang rawat jalan dengan sampel sebanyak 138 responden. Analisis yang digunakan dalam penelitian ini adalah analisis jalur (path analysis). Hasil penelitian ini menunjukkan bahwa terdapat pengaruh langsung secara signifikan antara the big five personality terhadap OCB, OCB terhadap kinerja perawat dengan nilai signifikansi sebesar 0,000 (<0,05). Tidak terdapat pengaruh secara signifikan antara the big personality terhadap kinerja perawat dengan nilai signifikansi sebesar 0,374 (>0,05). Terdapat pengaruh the big five personality terhadap kinerja perawat melalui OCB sebagai variabel mediasi dengan nilai signifikansi sebesar <0,000 (<0,05). Dapat disimpulkan bahwa OCB berpengaruh penuh sebagai variabel mediasi antara the big five personality terhadap kinerja perawat.
Pengaruh Managemen Complain Terhadap Loyalitas Di Moderasi Dengan Kepuasan
Authors: Rauf Rabihatun , Rauf Rabihatun , Parenta Mappamiring 
Published: November 2024

Penelitian ini bertujuan untuk mengetahui Manajemen Complain terhadap loyalitas serta variaabel kepuasan dapat memoderasi variabel complain terhadap loyalitas pasien. Penelitian ini diadakan di Rumah Sakit Syech Yusuf sampel pada penelitian ini berjumlah 240 responden. Penelitian ini menggunakan desain penelitian kuantitatif dengan metode penelitian pendekatan cross sectional study. Teknik analisis yang di gunakan adalah path analysis dengan menggunakas software WarpPls 7.0. Hasil penelitian menujukkan bahwa variabel complain terhadap kepuasan berpengaruh positif dengan nilai path coeffisient nya sebesar 0.393 yang jika dipersentasikan sebesar 39,3% dan nilai P-Value nya sebesar <0.001 yang menandakan variabel complain terhadap loyalitas berpengaruh signifikan dan variabel Kepuasan signifikan memoderasi pengaruh variabel manajemen complain terhadap loyalitas dengan nilai P- Value sebesar 0.001 serta berpengaruh positif dengan nilai path coeffisient 0.387 yang apabila dipersentasikan sebesar 38,7%.
Rational Design of Carbon‐Rich Materials for Energy Storage and Conversion
Authors: Kong Debin , Gao Yang , Xiao Zhichang , Xu Xiaohui , Li Xianglong , Zhi Linjie 
Published: October 2018

AbstractCarbon‐rich materials have drawn tremendous attention toward a wide spectrum of energy applications due to their superior electronic mobility, good mechanical strength, ultrahigh surface area, and more importantly, abundant diversity in structure and components. Herein, rationally designed and bottom‐up constructed carbon‐rich materials for energy storage and conversion are discussed. The fundamental design principles are itemized for the targeted preparation of carbon‐rich materials and the latest remarkable advances are summarized in terms of emerging dimensions including sp2 carbon fragment manipulation, pore structure modulation, topological defect engineering, heteroatom incorporation, and edge chemical regulation. In this respect, the corresponding structure–property relationships of the resultant carbon‐rich materials are comprehensively discussed. Finally, critical perspectives on future challenges of carbon‐rich materials are presented. The progress highlighted here will provide meaningful guidance on the precise design and targeted synthesis of carbon‐rich materials, which are of critical importance for the achievement of performance characteristics highly desirable for urgent energy deployment.
Graphen‐ähnlicher Kohlenstoff aus Biomasse: effiziente metallfreie Kohlenstoffkatalysatoren für Epoxidierungen
Authors: Wen Guodong , Gu Qingqing , Liu Yuefeng , Schlögl Robert , Wang Congxin , Tian Zhijian , Su Dang Sheng 
Published: October 2018

AbstractN‐dotierte graphenartige Kohlenstoffe (NG) wurden über eine metallfreie Syntheseroute durch Pyrolyse aus Glucose, Fructose und 5‐Hydroxymethylfurfural (5‐HMF) synthetisiert, welche günstig aus weithin verfügbarer Biomasse gewonnen werden können. Vor allem durch den Einsatz von 5‐HMF als Kohlenstoffquelle konnte ein NG mit einer gut entwickelten, dünnen Schichtstruktur mit großer lateraler Ausdehnung hergestellt werden. Der von 5‐HMF abgeleitete NG zeigte im Vergleich zu herkömmlichen Kohlenstoffkatalysatoren eine überlegene Leistung bei Epoxidierungen, vergleichbar mit der eines Cobaltkatalysators. Charakterisierungen der NGs mittels TEM und XPS sowie EPR‐Analysen ergaben, dass die katalytischen Eigenschaften auf ein hohes Aktivierungsvermögen sowohl für Alkene als auch für O2 zurückzuführen sind. Die Fähigkeit zur Substrataktivierung konnte dabei einerseits auf die graphitische Schichtstruktur und andererseits auf in das Graphitgitter eingebundene N‐Spezies zurückgeführt werden.
Investigation of the Locked‐Unlocked Mechanism in Living Anionic Polymerization Realized with 1‐(Tri‐isopropoxymethylsilylphenyl)‐1‐phenylethylene
Authors: Liu Pibo , Ma Hongwei , Han Li , Shen Heyu , Yang Lincan , Li Chao , Hao Xinyu , Li Yang 
Published: October 2018

AbstractReported is an intriguing advance in living anionic polymerization (LAP) by a “locked‐unlocked” mechanism in which the living anionic species can be quantitatively locked by end‐capping with 1‐(tri‐isopropoxymethylsilylphenyl)‐1‐phenylethylene (DPE‐Si(O‐iPr)3) and can be unlocked by adding the key, sodium 2,3‐dimethylpentan‐3‐olate (NaODP). These new insights into this mechanism were carefully confirmed by designing reactions involving sequential feeding of quantitative DPE‐Si(O‐iPr)3 and traditional monomers mixed with NaODP, and subsequently characterizing the corresponding samples, taken during the feeding process, by GPC, NMR, and MALDI‐TOF‐MS techniques. The switch from the locked to unlocked state was clearly confirmed by these characterization techniques. The putative locked‐unlocked mechanism in the LAP was simulated by the Gaussian method. This intriguing mechanistic finding of LAP reactions is expected to supplement the existing knowledge and facilitate the tailoring of specific structures for these polymerizations.
Measuring Therapeutic Changes for a British Chinese Family UsingSCORE‐15
Authors: Teh Yang Yang , Lek Evonne 
Published: October 2018

This paper details the findings and reflections of family therapy treatment outcomes for a British‐Chinese family usingSCORE‐15, a reliable and valid systemic outcome measure developed in theUK. It aims to examine the clinical usefulness ofSCORE‐15 through its application to a single case study. The two culture‐specific treatments were conducted at the Marlborough Cultural Therapy Centre (MCTC), which was part of the Marlborough Family Service in London.MCTCwas a mental health specialist service for ethnic minorities in their preferred languages that operated for 18 years within the mainstream mental health setting of the National Health Service (NHS). The overall family functioning was found to have improved and problem severity decreased, apart from some aspects rated by the mother. Reflections and discussions with the family with regard to theSCORE‐15 findings facilitated understanding and feedback about clinical changes in the systemic intervention.
Seasonal differences in drivers of species richness of waders in inland wetlands of La Mancha Húmeda Biosphere Reserve
Authors: Gonçalves Maycon Sanyvan Sigales , Gil‐Delgado José Antonio , Gosálvez Rafael U. , López‐Iborra Germán Manuel , Ponz Adrián , Velasco Ángel 
Published: October 2018

Abstract

Temporary inland wetlands are among the most threatened ecosystems worldwide, and recognition of the factors that determine species richness in different seasons is key for developing conservation plans for these systems. La Mancha Húmeda Biosphere Reserve in central Spain has many inland wetlands of this type, but the driving ecological processes of species richness are poorly understood.
This study examines the association of landscape and local variables with species richness patterns of inland wetlands of La Mancha Húmeda Biosphere Reserve during winter and the breeding season. The number of lakes in several increasing radii was a proxy of connectivity, and maximum flooded surface and shoreline length were surrogates of the species–area relationship.
Other landscape and local habitat variables, such as hydroperiod (length of inundation period), distance from human settlements, shoreline development index, vegetation surface cover, average lake depth, number of islands and surface area of islands were also analysed. Hierarchical partitioning analysis was used to evaluate the contribution of the environmental variables to explain the species richness of waders.
Species richness (26 species, four threatened in Europe) had different associations with the variables during the wintering and breeding seasons. The richness of breeding and wintering species was positively associated with hydroperiod and maximum flooded surface area respectively. No variable measured was negatively associated with species richness in any season.
Hydroperiod and flooded surface area are altered directly by human activities. Water extraction for irrigation reduces hydroperiod in some wetlands, whereas wastewater input extends hydroperiod in others, promoting wader concentrations in lakes flooded in summer and potentially favouring botulism outbreaks. In addition, the lack of protection and management on most of the lakes in La Mancha Húmeda Biosphere Reserve also favours encroachment of agriculture, destroying and degrading habitat for wintering and breeding waders.
Maxilloturbinal Aids in Nasophonation in Horseshoe Bats (Chiroptera: Rhinolophidae)
Authors: Curtis Abigail A. , Smith Timothy D. , Bhatnagar Kunwar P. , Brown Alexis M. , Simmons Nancy B. 
Published: October 2018

ABSTRACTHorseshoe bats (Family Rhinolophidae) show an impressive array of morphological traits associated with use of high duty cycle echolocation calls that they emit via their nostrils (nasophonation). Delicate maxilloturbinal bones inside the nasal fossa of horseshoe bats have a unique elongated strand‐like shape unknown in other mammals. Maxilloturbinal strands also vary considerably in length and cross‐sectional shape. In other mammals, maxilloturbinals help direct respired air and prevent respiratory heat and water loss. We investigated whether strand‐shaped maxilloturbinals in horseshoe bats perform a similar function to those of other mammals, or whether they were shaped for a role in nasophonation. Using histology, we studied the mucosa of the nasal fossa in Rhinolophus lepidus, which we compared with Hipposideros lankadiva (Hipposideridae) and Megaderma lyra (Megadermatidae). Using micro‐CT scans of 30 horseshoe bat species, we quantified maxilloturbinal surface area and skull shape within a phylogenetic context. Histological results showed horseshoe bat maxilloturbinals are covered in a thin, poorly vascularized, sparsely ciliated mucosa poorly suited for preventing respiratory heat and water loss. Maxilloturbinal surface area was correlated with basicranial width, but exceptionally long and dorsoventrally flat maxilloturbinals did not show enhanced surface area for heat and moisture exchange. Skull shape variation appears to be driven by structures linked to nasophonation, including maxilloturbinals. Resting echolocation call frequency better predicted skull shape than did skull size, and was specifically correlated with dimensions of the rostral inflations, palate, and maxilloturbinals. These traits appear to form a morphological complex, indicating a nasophonatory role for the strand‐shaped rhinolophid maxilloturbinals. Anat Rec, 2018. © 2018 American Association for Anatomy.
Landmark Typology in Applied Morphometrics Studies: What's the Point?
Authors: Wärmländer Sebastian K. T. S. , Garvin Heather , Guyomarc'h Pierre , Petaros Anja , Sholts Sabrina B. 
Published: October 2018

ABSTRACTLandmarks are the hallmark of biological shape analysis as discrete anatomical points of correspondence. Various systems have been developed for their classification. In the most widely used system, developed by Bookstein in the 1990s, landmarks are divided into three distinct types based on their anatomical locations and biological significance. As Bookstein and others have argued that different landmark types possess different qualities, e.g., that Type 3 landmarks contain deficient information about shape variation and are less reliably measured, researchers began using landmark types as justification for selecting or avoiding particular landmarks for measurement or analysis. Here, we demonstrate considerable variation in landmark classifications among 17 studies using geometric morphometrics (GM), due to disagreement in the application of both Bookstein's landmark typology and individual landmark definitions. A review of the literature furthermore shows little correlation between landmark type and measurement reproducibility, especially when factors such as differences in measurement tools (calipers, digitizer, or computer software) and data sources (dry crania, 3D models, or 2D images) are considered. Although landmark typology is valuable when teaching biological shape analysis, we find that employing it in research design introduces confusion without providing useful information. Instead, researchers should choose landmark configurations based on their ability to test specific research hypotheses, and research papers should include justifications of landmark choices along with landmark definitions, details on landmark collection methods, and appropriate interobserver and intraobserver analyses. Hence, while the landmarks themselves are crucial for GM, we argue that their typology is of little use in applied studies. Anat Rec, 302:1144–1153, 2019. © 2018 Wiley Periodicals, Inc.
The impact of low temperature on fraction unbound for plasma and tissue
Authors: Ryu Sangwoo , Novak Jonathan J. , Patel Roshan , Yates Phillip , Di Li 
Published: October 2018

AbstractThe effect of low temperature (4 °C) on plasma protein binding and tissue binding was evaluated for the first time using a large set of structurally diverse compounds covering a wide range of physiochemical properties and fraction unbound values. These results show that temperature has little effect on plasma protein binding and tissue binding and that the measured binding values at 4 °C are equivalent, on average, to those at physiological temperature (37 °C). The exception is indomethacin, where binding component(s) changed during long incubation at 37 °C. These data suggest that binding experiments can be conducted at 4 °C for unstable compounds in early drug discovery. Furthermore, plasma protein binding and tissue binding are likely to have little change during hypothermia conditions.
CYP2J2 is the major enzyme in human liver microsomes responsible for hydroxylation of SYL‐927, a novel and selective sphingosine 1‐phosphate receptor 1 (S1P1) agonist
Authors: Yang Shu , Hu Jinping , Li Yan , Zhao Zhigang 
Published: October 2018

AbstractSYL‐927, a novel and selective S1P1 agonist, is transferred to its active phosphate for the regulation of lymphocyte recirculation. This in vitro metabolism study is to elucidate the P450‐mediated oxidation pathway of SYL‐927 in human liver microsomes (HLMs). The results demonstrated that the ω‐1 hydroxylated metabolite SYL‐927‐M was formed after incubation of SYL‐927 with HLMs. Recombinant human CYP1A1 and CYP2J2 can efficiently catalyse SYL‐927‐M formation, followed by markedly less substrate conversion with CYP1A2, CYP2C19 and CYP2D6. Inhibition studies with chemical inhibitors and antibodies suggested that arachidonic acid, the substrate of CYP2J2, and CYP2J2‐specific antibody effectively inhibited the formation of SYL‐927‐M in HLMs whereas no significant inhibition was observed with the inhibitors for CYP1A1, CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP2E1 and CYP3A4, demonstrating that CYP2J2 was primarily responsible for the formation of SYL‐927‐M.
Effect of Gd3+, Bi3+, or Sm3+ on luminescent properties of La2−xMgTiO6:xEu3+ phosphors
Authors: Xie Huidong , Su Binbin , Tan Yurong , Zhao Yajuan , Chai Shouning 
Published: October 2018

AbstractSingle phase of Bi3+, Gd3+, Sm3+ and Eu3+ co‐doped La2MgTiO6 red phosphors were synthesized by high temperature solid‐state method. The phase composition, morphology and fluorescent properties of the phosphors were analyzed by X‐ray diffraction (XRD), scanning electron microscopy (SEM) and fluorescence spectrometer. The La2‐xMgTiO6:xEu3+ phosphors can be excited by UV (396 nm) and blue (465 nm) light‐emitting diode (LED) chips and show a strong red emitting with dominated wavelength at 615 nm. The optimum doping concentration of Eu3+ ion for La2MgTiO6 is x = 0.5. The luminescent intensities of 5D0 → 7F2 transition of Eu3+ in La1.5‐yMgTiO6:0.5Eu3+, yBi3+/Gd3+/Sm3+ were 1.31 times, 1.32 times and 1.88 times that of La1.5MgTiO6:0.5Eu3+ at y = 0.08, 0.06, 0.06 for Bi3+, Gd3+, or Sm3+ sensitizer, respectively. The chromaticity coordinates of La1.44MgTiO6:0.5Eu3+, 0.06Sm3+, (0.6342, 0.3513) were very close to those of the National Television Standard Committee (NTSC) standard red light coordinates.
Gram‐scale production of carrier‐free fluorescent berberine microrods for selective liver cancer therapy
Authors: Zheng Xiao , Zhang Fan , Shao Dan , Zhang Zhanqiang , Cui Lianzhi , Zhang Jing , Dawulieti Jianati , Meng Zhaojie , Zhang Ming , Chen Li 
Published: October 2018

AbstractBerberine, a widely used isoquinoline alkaloid in traditional Chinese medicine, has been proved to be a potential candidate in liver cancer therapy. However, the low therapeutic dose in the tumor target which is due to the poor solubility and oral bioavailability has limited its clinical application. In this study, fluorescent self‐carried Berberine microrods (Ber‐MRs) were prepared in gram‐scale through a facile and cheap antisolvent precipitation method. Ber‐MRs exhibited good optical properties, pH‐responsive drug release behavior and selective and safe antitumor performance in vitro and in vivo without obvious toxicity. These findings have demonstrated that Ber‐MRs are promising for efficient and safe liver cancer therapy. © 2018 BioFactors, 44(5):496–502, 2018
Spatial distribution of mammography adherence in a Swiss urban population and its association with socioeconomic status
Authors: Sandoval José Luis , Himsl Rebecca , Theler Jean‐Marc , Gaspoz Jean‐Michel , Joost Stéphane , Guessous Idris 
Published: October 2018

AbstractPurposeLocal physical and social environment has a defining influence on individual behavior and health‐related outcomes. However, it remains undetermined if its impact is independent of individual socioeconomic status. In this study, we evaluated the spatial distribution of mammography adherence in the state of Geneva (Switzerland) using individual‐level data and assessed its independence from socioeconomic status (SES).MethodsGeoreferenced individual‐level data from the population‐based cross‐sectional Bus Santé study (n = 5002) were used to calculate local indicators of spatial association (LISA) and investigate the spatial dependence of mammography adherence. Spatial clusters are reported without adjustment; adjusted for neighborhood income and individual educational attainment; and demographic factors (age and Swiss nationality). The association between adjusted clusters and the proximity to the nearest screening center was also evaluated.ResultsMammography adherence was not randomly distributed throughout Geneva with clusters geographically coinciding with known SES distributions. After adjustment for SES indicators, clusters were reduced to 56.2% of their original size (n = 1033). Adjustment for age and nationality further reduced the number of individuals exhibiting spatially dependent behavior (36.5% of the initial size). The identified SES‐independent hot spots and cold spots of mammography adherence were not explained by proximity to the nearest screening center.ConclusionsSES and demographic factors play an important role in shaping the spatial distribution of mammography adherence. However, the spatial clusters persisted after confounder adjustment indicating that additional neighborhood‐level determinants could influence mammography adherence and be the object of targeted public health interventions.
A novel unembalmed human cadaveric limb model for assessing conformational changes in self‐expanding nitinol stents in the popliteal artery
Authors: Shurtleff Eric , Vanderhyde Mariam , Fitzwater Fallon , Masoomi Reza , Maletsky Lorin , Thomas Pamela , Vamanan Karthik , Gupta Kamal 
Published: October 2018

AbstractObjectiveTo develop an unembalmed human cadaveric lower limb model as a more realistic environment for testing self‐expanding nitinol stents. We studied conformational changes and strain induced by knee flexion in nitinol stents deployed in the popliteal artery (PA).MethodsOne Lifestent® each was deployed into one limb of four cadavers (control group), while the contralateral leg received a different stent (Absolute®, Protégé Everflex®, Supera®, and Gore Viabahn®). The limbs were mounted on a quasi‐static knee rig (QKR) and X‐ray imaging was performed at pre‐defined knee flexion angles. A least‐squares solution to the equation of a circle was used to assess radius of curvature at flexion points (FP), and nominal strain was calculated for each stented artery.ResultsThere were differences but also some similarities in conformational changes seen in the various stents. Knee flexion produced at least two FP in all stents. The mean radius of curvature decreased with increasing degrees of flexion but more so in distal (main) than proximal (accessory) FP (22 mm vs. 11 mm) in all stents. Supera® stent had the greatest relative radii of curvatures, and Absolute® stent had the highest strain value in comparison to the contralateral PA as the control group.ConclusionThis study describes a novel human cadaveric limb model for testing self‐expanding nitinol stents implanted in the PA. Several parameters of conformational change in the stented PA such as FP formation, FP translocation and strain induced by axial compression were described. These may be useful for developing new stents for the PA location.
A double‐hit High‐grade B‐cell lymphoma with three‐way translocation t(3;8;14)(q27;q24;q32) involving BCL6, MYC, and IGH
Authors: De Paoli Elena , Bandiera Laura , Ravano Emanuele , Cesana Clara , Grillo Giovanni , Mancini Valentina , De Canal Gabriella , Bonoldi Emanuela , Soriani Silvia 
Published: October 2018

Key Clinical MessageWe describe an High‐grade B‐cell lymphoma case, in which a complex translocation t(3;8;14) with effects on the genes BCL6, MYC, and IGH, was detected. This case could be the first double‐hit lymphoma with a single chromosome rearrangement causing the double effect with three genes involved.