bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short-term stock indices as a tool for assessing and forecasting scientific and technological security
Authors: Ladynin A. I. 
Published: December 2024

Objectives. Ensuring scientific and technological sovereignty, defined as one of the objectives of the Concept of Technological Development for the period until 2030, approved by the Order of the Government of the Russian Federation No. 1315-r dated May 20, 2023, implies the use of effective mechanisms for managing the country’s economy. Under contemporary conditions, technology is a crucial element in the country’s economic development and a key component of scientific and technological security. Thus, the aim of the present work is to develop existing methods for analyzing economically significant information relating to the monitoring and diagnostics of scientific and technological security at the meso- and macrolevels.Methods. The developed method for scientific and technological security level monitoring and forecasting, which is based on the dynamics analysis of the values of corporate securities, includes economic and statistical analysis methods, machine learning and time series analysis tools.Results. The approach towards information processing and enhancement of analysis mechanisms in managerial decisions, which relies on diagnostic, analysis, and forecasting tools for socioeconomic system scientific and technological security, is based on information-processing, economic, and mathematical methods. The presented results constitute a developed method for the analysis of systemically important enterprises stock indices, supporting research and development to assess and predict scientific and technological security dynamics at meso- and macro levels of the economy. In order to verify the methodology, a numerical experiment was carried out using statistical data from systemically important companies.Conclusions. The developed methodology is aimed at improved managerial decision-making accuracy and speed when solving problems connected with scientific and technological security underpinning socioeconomic systems. The experimental results quantitatively confirm the significant contribution made by systemically important companies to Russian Federation’s scientific and technological security ensuring.
Contribution of interference to the magneto-optical transverse Kerr effect in white light
Authors: Gladyshev I. V. , Yurasov A. N. , Yashin M. M. 
Published: December 2024

Objectives. When measuring the transverse Kerr effect on thin-film structures, interference effects have a great influence on the result obtained. In conference presentations, some researchers have reported on the use of white light in experiments. In their opinion, despite the thickness of the studied layers being much less than the wavelength of light, white light can help avoid interference effects and/or resonant excitation of plasmon waves. The aim of the present work is to verify the validity of such statements using simulation.Methods. In order to solve this problem, the method of computer simulation was used. A numerical solution of equations was compiled for a model structure for various thicknesses and materials of layers.Results. The simulation results show that interference effects in different parts of the spectrum when using white light sources do not neutralize each other. The magnitude of the effect is affected not only by the thickness of the structure layers, but also by the shape of the source emission spectrum, as well as the sensitivity curve of the photodetector. In this case, the output of the measured value of the effect to a plateau at relatively large thicknesses of the magnetooptical film is due to the light being absorbed in the thickness of the magneto-optical film and is negligibility of the back reflection of light from the substrate.Conclusions. The presented technique takes into account the influence of interference effects when measuring the equatorial Kerr effect in white light or using other sources having a wide spectral range, thus improving the interpretation of experimental results. The results are relevant to the development and research of the physical foundations for creating new and improving existing devices in micro-, nano-, and solid-state electronics, as well as quantum devices, including optoelectronic devices and converters of physical quantities.
Cybersecurity of smart grids: Comparison of machine learning approaches training for anomaly detection
Authors: Kochergin S. V. , Artemova S. V. , Bakaev A. A. , Mityakov E. S. , Vegera Zh. G. , Maksimova E. A. 
Published: December 2024

Objectives. The transformation of modern electric grids into decentralized smart grids presents new challenges in the field of cybersecurity. The purpose of this work is to conduct research and analysis into the effectiveness of different machine-learning methods for identifying anomalies in decentralized smart networks, including cyberattacks and emergency modes, as well as to develop recommendations on the optimal combination of these methods for ensuring effective cybersecurity under conditions of changing electrical loads.Methods. We consider several machine learning methods for identifying anomalies in power systems that simulate network behavior under conditions of cyberattacks and emergency modes. The relative effectiveness of such methods as multifractal analysis using wavelets, the Isolation Forest model, local outlier factor (LOF), k-means clustering, and one-class support vector machine (One-Class SVM), is analyzed.Results. The comparison of machine learning methods reveals the varying effectiveness of anomaly detection methods used to detect cyber threats and deviations in electrical systems. Isolation Forest is best at detecting abrupt changes related to cyberattacks with high accuracy and a minimum of false positives. While LOF can also be effective in detecting cyberattacks, its increased sensitivity to minor deviations increases the number of false positives. K-means and One-Class SVMs are less effective in detecting abrupt anomalies but are useful for general clustering of data and detecting both abrupt and smooth changes, respectively.Conclusions. The obtained research results indicate the advantages of using a combination of machine learning algorithms to ensure the reliable protection of smart networks from cyberattacks taking into account the nature of the electrical load.
Sedación paliativa en pacientes pediátricos con cáncer avanzado en cuidado paliativo
Authors: Aedo M. Mónica , Rodríguez Z. Natalie , Palma T. Chery , Yohannessen V. Karla 
Published: December 2024

Los cuidados paliativos (CP) tienen un rol fundamental en la población pediátrica que padece cáncer, existiendo escasas publicaciones sobre el procedimiento de sedación paliativa (SP) en pediatría. Objetivo: Describir las características de los pacientes atendidos en la Unidad de CP del hospital de niños Dr. Roberto del Río, con diagnóstico oncológico en etapa avanzada que recibieron SP. Pacientes y Método: Estudio descriptivo retrospectivo. Se revisaron historias clínicas de niños, niñas y adolescentes (NNA) con cáncer avanzado que recibieron SP entre el 2003 y el 2021. Se caracterizaron variables demográficas y clínicas, asociadas a la práctica de SP. Resultados: Se incluyeron 204 pacientes con cáncer entre 2003-2021, el 22,5% recibió SP (46/204). Se revisaron 36 historias clínicas, edad promedio 8 años 7 meses, 56% hombres, 45% tumores sólidos. El síntoma refractario más frecuente fue disnea (50%). El 97% recibió midazolam en infusión continua. El tiempo transcurrido entre el inicio de SP y fallecimiento fue “mayor a 72 horas” en el 44% de los pacientes. La mayoría de los pacientes sedados (72%) fallecieron hospitalizados en unidades de baja complejidad. Conclusiones: La SP en NNA en CP por cáncer avanzado es una herramienta terapéutica, de uso ocasional, indicada frente a síntomas refractarios, permitiendo optimizar el manejo de pacientes en etapa de fin de vida. Se requieren más estudios multicéntricos para entregar orientaciones que incluyan pacientes con patología no oncológica.
Risk Factors, Causes, and Strategies for Reducing Medication Errors: A Narrative Review
Authors: Nadem Suha , Makarim M. Ali Hassan  , Amena Lafeta Muttlaq Al-Shareefi  
Published: December 2024

Abstract— Medication errors, which refer to any deviation from the prescribed medication regimen, can have seriously affected patient safety and treatment outcomes. It underscores the need for healthcare professionals to follow medication orders precisely and to be vigilant in preventing errors throughout the medication use. This process involves different stakeholders, including specialists, therapists, apothecaries, patients, and their relatives. Medication errors tend to be more prevalent in hospital settings due to various factors related to the complexity of patient care, the fast-paced environment, and the involvement of multiple healthcare professionals in the medication process. The current review was conducted for reporting medication errors, risk factors, causes, and strategies for reducing medication errors in previous articles from 2015 to 2023. The brief review showed that multiple studies have reported a high incidence of medication errors following hospital discharge. These errors can include prescribing errors, incorrect dosing, medicine interactions, and omissions or duplications of medication. Medication errors following hospital discharge can lead to adverse drug events, which can result in patient harm, hospital readmissions, and increased healthcare costs. Also; some studies have evaluated the effectiveness of transitional care interventions and strategies in reducing medication errors and adverse drug events (ADEs). These interventions can include medication reconciliation processes, post-discharge follow-up, patient education programs and electronic medication management system. By addressing these interventions, future studies and interventions can contribute to improving medication safety following hospital discharge and advancing the global safety agenda.
GC-MS Assay to Alkaloid Extract of T. foenum-graecum Seeds and Detection Effect of Extract as Antibacterialect Of Extract As Antibacterial
Authors: Sura Salim Nadhm  , AL-Waheeb Alla N. 
Published: December 2024

The need for standardized modern analytical procedures becomes urgent due to the rise in drug-resistant for pathogens. These procedures use to isolate new bioactive compounds from medicinal plants. The medicinal plant-derived compounds could provide a new method to fight pathogenic bacteria. This study sheds light on the antimicrobial activity of plant-derived components, their possible mechanisms of action, and their chemical potential. Five different plant extract concentrations were used:12.5, 25, 50, 100, and 200 mg/ ml. The maximum inhibition zone for the alkaloid extracted from seeds of Trigonella foenum against Klebsiella pneumonia was (21.0 ± 0.63) mm at 200 Mg ml1 dose. In comparison, the minimum inhibition zone for Pseudomonas aeruginosa was (6.16 ± 0.40) mm at 25 Mg ml1. According to the results of the gas chromatography-mass spectrometry (GC-MS) analysis, the chemical composition analysis of the Trigonella foenum extract had a high concentration of organic components with antimicrobial and antioxidant properties.
Presentación vol. 15 Núm. 1 (2023) revista El Taller de la Historia
Authors: Solano Sergio Paolo 
Published: December 2024

La revista El Taller de la Historia llega a la edición número 18, correspondiente al primer semestre del 2023. Esta entrega corresponde a la número siete desde que se semestralizó en el año 2020. Pese a las dificultades debido al incremento de la cantidad de revistas de historia en todo el mundo, muchas de ellas especializadas hasta por temas muy puntuales, El Taller de la Historia se ha mantenido con una alta calidad. De un total de 155 artículos publicados hasta el presente número, el 81,3 % corresponden a autores externos a la Universidad de Cartagena. Los nacionalidades de los autores son diversas: estadounidenses, mexicanos, guatemaltecos, costarricenses, venezolanos, brasileros, peruanos, uruguayos, argentinos, chilenos, españoles y franceses
Ecclesiae Filius
Authors: Nascimento Neto Josebias Costa do , Moura Filha Maria Berthilde de Barros Lima e , Valadares Pedro Henrique Cabral 
Published: December 2024

A cidade do Recife, capital de Pernambuco, assim como outras capitais luso-brasileiras, possui um rico conjunto de pátios católicos que moldaram seu tecido urbano. As pesquisas que analisam como esses espaços, entetanto, foram desenvolvidos e integrados ao contexto urbano ainda são esparsas. Logo, considerando o impacto das igrejas e seus pátios nas práticas sociais e configuração do espaço público; esta pesquisa visa construir uma narrativa acerca dessa herança socioespacial, atribuído ao pátio de São Pedro no Recife-PE, como resultado da hegemonia cristã na produção arquitetônica e urbanística do período colonial brasileiro. Partindo desse princípio, fez-se uma revisão bibliográfica acerca da construção e consolidação das cidades luso-brasileiras sob a ótica da contribuição e sua notória influência cultural, enquanto colônia de Portugal. Portanto, confirma-se a hipótese inicial do trabalho, tendo em vista que o Pátio de São Pedro transcende sua exordial função religiosa e se institui como um espaço multifacetado de memória e identidade na cidade do Recife. Desse modo, pode-se inferir que o objeto de pesquisa têm a sua relevância alicerçada em sua historiografia socioespacial, em seus usos e funções ao longo dos séculos, bem como também em seu traçado urbanístico que remonta a experiência do período colonial do Brasil. Logo, a história do Pátio está intrinsecamente ligada à história da sociedade recifense, sendo este um espaço onde, ao longo dos séculos, as celebrações, sejam profanas e/ou sagradas, os eventos culturais, os comércios e serviços de seu entorno; juntos fortaleceram os traços socioespaciais deste lugar. Assim, o tombamento do local pelo Instituto do Patrimônio Histórico e Artístico Nacional (Iphan) ratifica sua importância cultural, enquanto um bem patrimonial, e reafirma um compromisso com a preservação desse valioso conjunto edificado para as gerações descendentes.
Palavras-chave: Patrimônio cultural. Recife (PE). Pátio de São Pedro.
Cultura popular
Authors: Silva Natasha Hevelyn Oliveira da , Sousa João Morais de 
Published: December 2024

No contexto dos estudos culturais, este artigo tem como objetivo discutir o conceito de Cultura Popular, no recorte da manifestação popular do Coco de Roda em Igarassu, dentro de perspectiva sociológica que compreende a cultura popular como resistente ao mercado e às estruturas de poder dominantes. No aporte teórico, a cultura é compreendida como um sistema de símbolos (Geertz, 1978) construído mediante o processo de socialização, ou seja, trata-se dos costumes, hábitos, códigos e crenças que são aprendidos pelos sujeitos a partir da sua inserção na sociedade (Laraia, 2020). Faz-se necessário compreender a cultura como um processo social e material, de modo que as questões relativas à economia não estão separadas da cultura, compondo uma totalidade indissociável. Nessa ótica, a acepção da cultura está intimamente conectada aos conflitos sociais, às questões políticas e todo o arcabouço das relações de poder presente nas sociedades (Canclini, 1983; Williams, 2011). E a cultura popular como referente às tradições, costumes, usos e memórias das classes populares (Bosi, 2000), em que também prepondera o conflito e se estabelece um limiar entre agência e estrutura. Nesse sentido, a cultura popular é compreendida como tenaz e com capacidade para resistir e construir alternativas contra-hegemônicas (Gramsci, 1995; Thompson, 1998). No que tange à metodologia, utilizamos o método qualitativo (Minayo, 2001), uma vez que intentamos uma investigação dos aspectos simbólicos relativos à vivência dessa manifestação. Como técnica de coleta de dados utilizou-se a estratégia da observação direta e participante, e entrevistas semiestruturadas com fazedores do Coco de Roda em Igarassu. Para a análise de dados, foi utilizada a perspectiva crítica de Guareschi (2014) e análise de conteúdo (Bardin, 1997). O resultado desta pesquisa sugeriu que essas manifestações populares vêm resistindo e contribuindo para a formação de agências participativas, solidárias e contra-hegemônicas. Portanto, o impacto social deste trabalho está em desvelar essas realidade, promover visibilidade para a temática e fortalecer a construção de outros trabalhos e políticas públicas que valorizem a cultura popular como parte do desenvolvimento de uma sociedade humana, integrada e diversa.
Palavras-chave: Cultura. Cultura Popular. Resistência.
GEMBALAKANLAH DOMBA-DOMBA-KU: Peningkatan Kompetensi Pelayanan melalui pemahaman kembali “Poda Tohonan Hasintuaon” di HKBP Se Ressort Tanjung Balai Kabupaten Asahan
Authors: Simanjuntak Pahala Jannen , Simanjuntak Parlaungan Christopel , Sianturi Frans Julu 
Published: December 2024

Sebagai pelayan gereja tentu perlu penyegaran kembali ‘mangarataratai’ ulaon hasintuaon-nya agar tetap memiliki kualitas yang baik dan menuju pelayanan ke arah yang lebih baik. Kenapa ini penting karena kita adalah pelayan gereja yang membutuhkan penyegaran, seperti sebuah HP yang perlu dichas kembali untuk bisa bertahan dan berfungsi dengan baik. Atau seperti tanam-tanaman yang perlu disiram agar pertumbuhannya baik dan segar dilihat orang kemudian menghasilkan buah yang baik. Tentu sebagai pelayan gereja telah dipilih dan bersedia mempersembahkan waktu dan tenaga untuk kerajaan Tuhan. Namun kita menyadari kita lemah dan terkadang tidak berdaya dengan berbagai kesulitan yang kita jalani. Namun kita harus tetap percaya bahwa Allah di dalam Yesus Kristus akan selalu memampukan kita. Artikel ini merupakan sebuah Pengabdian kepada Masyarakat (Pkm) di gereja HKBP Suka Maju yang melibatkan seluruh majelis di resort Tanjung Balai. Melalui pembinaan dan ceramah yang disampaikan para majelis semakin menghargai dan menekuni panggilannya sebagai Majelis di gereja HKBP sesuai dengan dokumen-dokumen HKBP yang bersumber dari Alkitab sebagai Firman Tuhan.
The role of inflammasome dysregulation in obstructive and non-obstructive azoospermia: a comparative molecular analysis of blood, tissue, and seminal plasma
Authors: Mirghanizadeh Bafghi Seyyed AmirHossein , Fesahat Farzaneh , Zare Fateme , Imani Maryam , Vahidi Serajoddin , Ansariniya Hossein , ZareHoroki Ali , Hadinedoushan Hossein 
Published: December 2024

BackgroundTo address knowledge gaps, this study aimed to investigate the involvement of inflammasomes in the etiology of azoospermia. This study focused on the gene expression of key inflammasome components, including NLR family pyrin domain containing 3 (NLRP-3), CASPASE-1, Interleukin-1β (IL-1β), Interleukin-18 (IL-18), NLR family CARD domain-containing protein 4/ice protease-activating factor (NLRC-4/IPAF), and Absent in melanoma 2 (AIM-2).MethodsWe analyzed gene expression in blood and testicular tissue from patients with obstructive azoospermia (OA) and non-obstructive azoospermia (NOA). Additionally, we compared IL-1β and IL-18 expression levels in seminal plasma samples using the Enzyme-Linked Immunosorbent Assay (ELISA) method. For comparison, blood samples from normospermic (NS) individuals were also genetically evaluated.ResultsOur results indicated significantly higher gene expression of inflammasome components in NOA patients than those in OA patients either in blood or in testicular tissue. Both azoospermic groups exhibited higher mRNA levels of inflammasome genes comparing with those from blood samples of NS men. Seminal plasma samples showed significantly increased levels of IL-1β and IL-18 in NOA patients compared to men with OA. The ROC curve analysis indicated strong and significant predictive power of IL-18, AIM-2 and NLRC-4/IPAF gene expression profiles between NOA vs. NS patients and NOA vs. OA.ConclusionsOur findings highlight the role of hidden chronic inflammation in azoospermia, particularly within the NOA group. This study provides a foundation for further detailed research, which could aid in the development of diagnostic panels to differentiate between various azoospermic groups.
Intra-arterial cocktail therapy for patients with anterior circulation large vessel occlusion who achieved endovascular reperfusion
Authors: Zhao Zi-Ai , Hu Hai-Zhou , Li Wei , Qiu Jing , Zhao Yong-Gang , Nguyen Thanh N. , Chen Hui-Sheng 
Published: December 2024

BackgroundClinically ineffective reperfusion (CIR) refers to the discrepancy between successful reperfusion and a favorable functional outcome in patients with large vessel occlusion (LVO) stroke after endovascular treatment (EVT). The Improving Neuroprotective Strategy for Ischemic Stroke with Sufficient Recanalization after Thrombectomy by Intra-arterial Cocktail Therapy (INSIST-CT) trial aimed to explore the safety, feasibility, and efficacy of intra-arterial cocktail therapy using argatroban, dexamethasone, and edaravone in patients who achieved sufficient reperfusion after EVT.MethodsIn this prospective, single-arm, pilot study, eligible patients with anterior circulation LVO who achieved sufficient reperfusion after EVT were enrolled in the INSIST-CT trial. Consecutive patients who met the inclusion/exclusion criteria were included in the control group retrospectively. In the INSIST-CT group, argatroban, dexamethasone, and edaravone were continuously administered for 30 min into the culprit artery after sufficient recanalization. The primary endpoint was the proportion of favorable functional outcome, defined as a modified Rankin Scale (mRS) score of 0–2 at 90 days. The primary safety outcome was symptomatic intracranial hemorrhage (sICH). Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) analyses were performed to account for multiple confounders.ResultsA total of 30 patients were included in the INSIST-CT group, and 261 patients were included in the control group. The proportion of the patients with the primary endpoint was 60% in the INSIST-CT group and 55.9% in the control group (unadjusted odds ratio [OR] 1.18, 95% CI 0.55–2.61, p = 0.67; adjusted OR 1.42, 95% CI 0.62–3.26, p = 0.41). No significant difference in sICH at 48 h after treatment was observed between the two groups (unadjusted OR 0.96, 95% CI 0.15–3.56, p = 0.96; adjusted OR 0.82 95% CI 0.17–3.97, p = 0.809). Similar results were observed after the PSM and IPTW analyses.ConclusionIn anterior circulation, LVO patients who achieved sufficient reperfusion after EVT, bridging intra-arterial cocktail therapy with argatroban, dexamethasone, and edaravone may be safe and feasible. However, it did not improve the 90-day functional outcomes. A numerically higher probability of a favorable outcome in the INSIST-CT group suggests the potential promise of this cocktail therapy in reducing clinically ineffective reperfusion.Clinical trial registrationClinicalTrials.gov, NCT04202549.