bluuebunny/crossref_metadata_2025_split huggingface dataset:
Making an exciting brand big: Brand personality, logo size and brand evaluation
Authors: Cai Yuanyuan , Mo Tingting 
Published: August 2019

AbstractThis research examines how brand personality (excitement) and logo size used in product design (big versus small) interacts in affecting consumer brand evaluation. We first demonstrate that combining a big logo and a high‐excitement brand (versus a small logo combined with a high‐excitement brand) leads to high processing fluency, further resulting in more favourable brand evaluation (Study 1). We then determine the consumption situation as a moderator of such an interaction effect: the influence of the big logo and high‐excitement‐brand combination on brand evaluation is significantly weakened in a private consumption situation (a T‐shirt worn at home) compared to a public consumption situation (a T‐shirt worn outside, Study 2a), and becomes insignificant for a private product category (slippers, Study 2b).
Reservation based resource allocation in 5G new radio standard
Authors: Saravanan Mohan , Kalidoss Rajakani , Partibane Bactavatchalame , Vishvaksenan Kuttathati Srinivasan 
Published: August 2019

SummaryIn fifth generation new radio, due to the increase in the number of mobile devices, there exist a demand for a large amount of spectrum. Resource scheduling service plays an important role to fulfill the demand for a large spectrum. To cater this spectrum crisis, a flexible and reliable reservation‐based spectrum sharing technique is proposed. The computational results shows that compared with existing techniques, the reservation‐based resource allocation (RBRA) technique can significantly increase the resource effective utilization, where not only the user with best channel characteristics is allocated the free spectrum but also a user with acceptable channel characteristics is assigned with free spectrum thereby maintaining the fairness.
Nexus of institutional pressures, environmentally friendly business strategies, and environmental performance
Authors: Majid Abdul , Yasir Muhammad , Yasir Muhammad , Javed Asad 
Published: August 2019

AbstractInstitutional pressures (IP) have a strong effect on organizational strategies and decision making. IP in terms of coercive, mimetic, and normative forces have a direct effect on organizations to develop environmentally friendly business strategies (EFBS) and improve environmental performance (EP). The aim of this study is to examine the effect of IP on EP. Moreover, the mediating role of EFBS in the relationship between IP and EP has also been tested. Results reveal that IP significantly and positively affect EFBS. Moreover, the relationship between EFBS and EP is also significantly positive. However, the direct relationship between IP and EP is weak. The results of the study also confirm that EFBS mediate the relationship between IP and EP. These findings suggest that managers should develop green strategies for the improvement of environmental performance. This study not only offers the empirical evidence to validate the findings of past researchers but also provides insight how IP flourish the mechanism of environmentally friendly business strategies. Furthermore, this study highlighted some interesting facts that should be meaningful options for managers to enhance the environmental performance.
Lossless Compression of Cytometric Data
Authors: Bras Anne E. , van der Velden Vincent H. J. 
Published: August 2019

AbstractNowadays, most cytometrists apply lossless compression by storing their FCS files in ZIP archives. Unfortunately, ZIP only achieves modest space savings in cytometric data, due to DEFLATE being used as the underlying lossless compression algorithm (LCA). Presumably, other modern LCA can outperform DEFLATE, especially in terms of space savings. Twenty‐one codecs (programs implementing LCA) were evaluated in 167,131 publicly available FCS files. Within floating‐point data, as produced by modern instruments, most favorable compression ratios (CRs) were achieved by ZPAQ (median 0.469), BCM (median 0.523), and LZMA (median 0.545). In comparison, the DEFLATE‐based codecs only achieved median CR of 0.728 under the most optimal conditions. By default, ZIP offers nine compression level (CL) settings, where lower ZIP‐CL optimizes for time efficiency, while higher ZIP‐CL optimizes for space efficiency. Interestingly, the third ZIP‐CL already resulted in near optimal CR in 90% of the files with floating‐point data, as produced by digital cytometers. LZMA is well established, widely supported, and actively maintained (in sharp contrast to ZPAQ and BCM) and therefore arguably the most attractive alternative for ZIP. Within floating‐point data, by shifting from ZIP (under optimal conditions) to LZMA (at default settings), the median CR can be improved by 25%. Based on our results, cytometrists can benefit from state‐of‐the‐art compression by choosing the appropriate codec for their situation. Our results are likely to speed‐up the adaptation of modern codecs, as CR around 0.5 were beyond all expectations, and such space savings will benefit the field of cytometry. © 2019 International Society for Advancement of Cytometry
Pulsed resource availability changes dietary niche breadth and partitioning between generalist rodent consumers
Authors: Stephens Ryan B. , Hobbie Erik A. , Lee Thomas D. , Rowe Rebecca J. 
Published: August 2019

AbstractIdentifying the mechanisms that structure niche breadth and overlap between species is important for determining how species interact and assessing their functional role in an ecosystem. Without manipulative experiments, assessing the role of foraging ecology and interspecific competition in structuring diet is challenging. Systems with regular pulses of resources act as a natural experiment to investigate the factors that influence the dietary niches of consumers. We used natural pulses of mast‐fruiting of American beech (Fagus grandifolia) to test whether optimal foraging or competition structure the dietary niche breadth and overlap between two congener rodent species (Peromyscus leucopus and P. maniculatus), both of which are generalist consumers. We reconstructed diets seasonally over a 2‐year period using stable isotope analysis (δ13C, δ15N) of hair and of potential dietary items and measured niche dynamics using standard ellipse area calculated within a Bayesian framework. Changes in niche breadth were generally consistent with predictions of optimal foraging theory, with both species consuming more beechnuts (a high‐quality food resource) and having a narrower niche breadth during masting seasons compared to nonmasting seasons when dietary niches expanded and more fungi (a low‐quality food source) were consumed. In contrast, changes in dietary niche overlap were consistent with competition theory, with higher diet overlap during masting seasons than during nonmasting seasons. Overall, dietary niche dynamics were closely tied to beech masting, underscoring that food availability influences competition. Diet plasticity and niche partitioning between the two Peromyscus species may reflect differences in foraging strategies, thereby reducing competition when food availability is low. Such dietary shifts may have important implications for changes in ecosystem function, including the dispersal of fungal spores.
A highly sensitive MEMS silicon‐hair device reproducing the function of hair follicle
Authors: Hamamoto Koki , Terao Kyohei , Shimokawa Fusao , Takao Hidekuni 
Published: August 2019

AbstractThis paper reports a highly sensitive MEMS silicon‐hair device with novel functions of hair follicle. Human hairy skin has peculiar receptor called hair follicle. Therefore, a highly sensitive sensor reproducing the function of hair follicle is demanded in order to quantify peculiar sense in hairy skin such as wind, static electricity, and perception of the liquid surface. The developed device in this study has fine silicon‐hair with 10 µm width and 5 mm length. Moreover, it detects two‐axis force and one‐axis moment applied to silicon‐hair by piezoresistors. The MEMS silicon‐hair device has realized resolutions of 5 µN axial force, 1 µN shear force, and 3nN·m moment. Also, the device in this study precisely acquired surface tension close to the physical property of water and ethanol water solution. In addition, the MEMS silicon‐hair device was successful in detecting 0.1 µN electrostatic attraction. Resolutions of shear force and moment have been improved by 10‐fold using the resonance‐drive of silicon‐hair.
Actor relations in climate policymaking: Governing decarbonisation in a corporatist green state
Authors: Kronsell Annica , Khan Jamil , Hildingsson Roger 
Published: August 2019

AbstractThis article focuses on the role of actor relations in advancing climate policymaking and argues that attempts to understand decisions to decarbonise in a green state should explore the institutional conditions for policymaking. The article explores the climate policy model in Sweden in terms of the societal actors included in the policy process, the nature of this inclusion, and its relevance for the prospects of decarbonisation. It uses three perspectives in the analysis: corporatism, sustainable transition studies, and ecological democracy. The findings largely support existing research that states characterised by corporatist policymaking are suited for environmental governance and for climate policymaking. However, as a model of governance of actor relations, the Swedish climate policymaking model has both its merits and demerits. Although it has potential to reach decarbonisation objectives, it does this in the context of including mainly established economic interests, that is, incumbents. This stands in contrast with what is argued in sustainable transition studies that incumbents obstruct change, in the Swedish case they are viewed as potential change agents. Finally, although the character of the actor relations is deliberative, it is a top–down exclusive kind of deliberation that remains far from ideals of ecological democracy.
Bystander Ethics and Good Samaritanism: A Paradox for Learning Health Organizations
Authors: Sabin James E. , Cocoros Noelle M. , Garcia Crystal J. , Goldsack Jennifer C. , Haynes Kevin , Lin Nancy D. , McCall Debbe , Nair Vinit , Pokorney Sean D. , McMahill‐Walraven Cheryl N. , Granger Christopher B. , Platt Richard 
Published: August 2019

AbstractIn 2012, a U.S. Institute of Medicine report called for a different approach to health care: “Left unchanged, health care will continue to underperform; cause unnecessary harm; and strain national, state, and family budgets.” The answer, they suggested, would be a “continuously learning” health system. Ethicists and researchers urged the creation of “learning health organizations” that would integrate knowledge from patient‐care data to continuously improve the quality of care. Our experience with an ongoing research study on atrial fibrillation—a trial known as IMPACT‐AFib—gave us some insight into one of the challenges that will have to be dealt with in creating these organizations. Although the proposed educational intervention study placed no restrictions on what providers and health plans could do, the oversight team argued that the ethical principle of beneficence did not allow the researchers to be “bystanders” in relation to a control group receiving suboptimal care. In response, the researchers designed a “workaround” that allowed the project to go forward. We believe the experience suggests that what we call “bystander ethics” will create challenges for the kinds of quality improvement research that LHOs are designed to do.
The Haves, the Have‐nots, and the Will‐nots
Authors: Mehlman Maxwell J. 
Published: August 2019

AbstractWhat if science enabled us to live an extended lifespan? Well, not us, but people in the future, and perhaps not everybody in the future, at least not at first. Should we allow and encourage science to develop this capability, or should we try to prevent or inhibit it? John Davis's book New Methuselahs: The Ethics of Life Extension is a thorough exploration of these questions. He presents the arguments for and against developing this capacity, and he considers three perspectives: those of individuals who will be able to extend their lives (the Haves), individuals who will not because they can't afford to (the Have‐nots), and individuals who will not extend their lives because they are opposed to doing so (the Will‐nots). Davis is a philosopher, and the bulk of this book is for the cognoscenti.
The Harms of a Penal Colony
Authors: Strong Justin 
Published: August 2019

AbstractMore than just a jail, Rikers has become a site of shifting discourse on punishment and justice in the United States. In the book Life and Death in Rikers Island, Homer Venters argues that the systematic failures of jails to provide appropriate safety and care constitute human rights violations and public health risks. The former chief medical officer and commissioner of correctional health services for the NYC Health and Hospitals system, Venters offers critical insight on the Rikers jail system. “Because jails are chaotic and concealed from outside view,” he asserts, “we only become aware of them when very bad outcomes occur, such as deaths.” Life and Death's success lies in how it blends Venters's experiences on the ground as a health care professional with the empirical data he's been able to collect and analyze over the tenure of his career. According to Venters, all suicides, homicides, and accidental deaths in jail are jail attributable, as they reflect system‐wide failures in safety.
Incentivizing organ donation through a nonmonetary posthumous award
Authors: Bedendo Mascia , Siming Linus 
Published: August 2019

AbstractSince 2013, The Order of St John Award for Organ Donation has been offered to the families of deceased solid organ donors in the United Kingdom to honor the donors and inspire others to donate. We evaluate the effects of this award using a difference‐in‐differences approach that builds on the fact that solid organ donors are eligible for the award, whereas cornea‐only donors are not. We find that the introduction of the award led to an increase in the number of deceased solid organ donors.
Magnetohydrodynamic bio‐nanoconvective Naiver slip flow of micropolar fluid in a stretchable horizontal channel
Authors: Zohra Fatema T. , Uddin Mohammed J. , Ismail Ahamd I. M. 
Published: August 2019

AbstractThe purpose of this paper is to formulate and analyze a nano‐bio transport model for magnetohydrodynamic convective flow, heat, and mass diffusion of micropolar fluid containing gyrotactic microorganisms through a horizontal channel. Both the walls are considered to be stretched, and the Navier slip boundary condition is taken into account. The governing bio‐nano transport partial differential equations are rendered to ordinary differential equations using similarity variables. The resulting normalized self‐similar boundary value problem is solved computationally with the Matlab bvp4c function. The effect of the controlling parameters on the nondimensional velocity, temperature, nanoparticle concentration, and motile microorganism density functions, and their gradients at the wall are visualized graphically and in a tabular form and expounded at length. Validation with a previous simpler model is included. All physical quantities, except the local Nusselt number, increases with an increase in the velocity slip and magnetic parameters. The present problem finds applications in industries related to pharmaceutical, nanofluidic devices, microbial enhanced oil recovery, modeling oil, and gas‐bearing sedimentary basins.
Improved exposure of bioactive peptides to the outermost surface of the polylactic acid nanofiber scaffold
Authors: Hsu Yu‐I , Yamaoka Tetsuji 
Published: August 2019

AbstractWe recently reported a novel method to modify the polylactic acid (PLLA) nanofiber scaffold with IKVAV peptide/oligo (d‐lactic acid) (ODLA) heteroconjugates. However, a part of the IKVAV sequence was not exposed to the outermost surface and therefore, cell adhesion was not optimized. In this study, we evaluated two strategies to improve the exposing efficiency of IKVAV. One strategy introduced a hydrophilic diethylene glycol (diEG) segment between IKVAV and ODLA. In the second method, these modified nanofibers were heated to a given temperature and cooled to room temperature in water. The IKVAV peptides at the outermost surface were quantified by the fluorescein isothiocyanate staining method. After being heated above the PLLA glass transition temperature, the exposing efficiency of the IKVAV sequence on the PLLA/ODLA–diEG–IKVAV nanofiber was three times higher than that on the PLLA/ODLA–IKVAV unheated nanofiber. Moreover, nearly 100% of the PC‐12 cells seeded onto the PLLA/ODLA–diEG–IKVAV nanofiber and were well distributed, while only 50% of the PC‐12 cells seeded onto the PLLA and PLLA/ODLA–IKVAV nanofibers. These strategies markedly enhanced the exposing efficiency of the bioactive peptides; therefore, their use can be applicable to other nanofiber scaffolds.
Diagnostic performance of multiparametric MRI in the evaluation of treatment response in glioma patients at 3T
Authors: Liu Jie , Li Cong , Chen Yinsheng , Lv Xiaofei , Lv Yanchun , Zhou Jian , Xi Shaoyan , Dou Weiqiang , Qian Long , Zheng Hairong , Wu Yin , Chen Zhongping 
Published: August 2019

BackgroundMRI is one of the most important techniques to assess the treatment response of gliomas. However, differentiating tumor recurrence (TuR) from treatment effects (TrE) remains challenging.PurposeTo compare the diagnostic performance of MR diffusion‐weighted imaging (DWI), arterial spin labeling (ASL), proton MR spectroscopy (MRS), and amide proton transfer (APT) imaging in differentiating between TuR and TrE in posttreatment glioma patients.Study TypeProspective.PopulationThirty patients with suspected tumor progression.Field Strength/SequenceDWI, ASL, proton MRS, and APT imaging were performed at 3T MR.AssessmentMR indices, including ADC, relative cerebral blood flow (rCBF), ratios of Cho/Cr, Cho/NAA, and NAA/Cr and APT‐weighted (APTw) effect were obtained from DWI, ASL, proton MRS, and APT imaging, respectively. Indices were measured in the contralateral normal‐appearing white matter and lesions defined on the Gd‐enhanced T1w image. TuR or TrE was either determined histologically or clinically from longitudinal MRI follow‐up for at least 6 months.Statistical TestsThe diagnostic performance of the indices was evaluated using Student's t‐test, receiver operating characteristic (ROC) curve, and multivariate logistic regression analyses.ResultsAmong the 30 patients, 16 were diagnosed as having TuR and the rest having TrE. The recurrent tumors showed a significantly higher APTw effect (1.56 ± 1.14%) and rCBF (1.44 ± 0.61) compared with lesions representing treatment effects (–0.44 ± 1.34% and 0.72 ± 0.25, respectively, with P < 0.001). The areas under the curve (AUCs) were 0.87 and 0.90 for APTw and rCBF, respectively, in differentiating between TuR and TrE. Combining APTw and rCBF achieved a higher AUC of 0.93. MRS index ratios of Cho/Cr (P = 0.25), Cho/NAA (P = 0.16), and NAA/Cr (P = 0.86) and ADC (P = 0.37) showed no significant differences between TuR and TrE lesions, with AUCs lower than 0.70.Data ConclusionCompared with DWI and MRS, ASL and APT imaging techniques showed better diagnostic capability in distinguishing TuR from TrE.Level of Evidence: 1Technical Efficacy: Stage 4J. Magn. Reson. Imaging 2020;51:1154–1161.
Multifunctional Cationic PeptoStars as siRNA Carrier: Influence of Architecture and Histidine Modification on Knockdown Potential
Authors: Holm Regina , Schwiertz David , Weber Benjamin , Schultze Jennifer , Kuhn Jasmin , Koynov Kaloian , Lächelt Ulrich , Barz Matthias 
Published: August 2019

AbstractRNA interference provides enormous potential for the treatment of several diseases, including cancer. Nevertheless, successful therapies based on siRNA require overcoming various challenges, such as poor pharmacokinetic characteristics of the small RNA molecule and inefficient cytosolic accumulation. In this respect, the development of functional siRNA carrier systems is a major task in biomedical research. To provide such a desired system, the synthesis of 3‐arm and 6‐arm PeptoStars is aimed for. The different branched polypept(o)idic architectures share a stealth‐like polysarcosine corona for efficient shielding and a multifunctional polylysine core, which can be independently varied in size and functionality for siRNA complexation‐, transport and intra cellular release. The special feature of star‐like polypept(o)ides is in their uniform small size (<20 nm) and a core–shell structure, which implies a high stability and stealth‐like properties and thus, they may combine long circulation times and a deep penetration of cancerous tissue. Initial toxicity and complement studies demonstrate well tolerated cationic PeptoStars with high complexation capability toward siRNA (N/P ratio up to 3:1), which can lead to potent RNAi for optimized systems. Here, the synthetic development of 3‐arm and 6‐arm polypept(o)idic star polymers, their modification with endosomolytic moieties, and first in vitro insights on RNA interference are reported on.
miR‐1249‐3p accelerates the malignancy phenotype of hepatocellular carcinoma by directly targeting HNRNPK
Authors: Shu Hongchun , Hu Jia , Deng Huiqiu 
Published: August 2019

AbstractBackgroundmicroRNAs (miRNAs) have been implicated to play crucial roles in carcinogenesis. miR‐1249‐3p was reported to be abnormally expressed in multiple human cancers. However, its biological role and the associated underlying mechanisms in hepatocellular carcinoma (HCC) remain largely unknown.MethodsmiR‐1249‐3p expression level in HCC cell lines and normal cell line was measured by quantitative real‐time PCR. Role of miR‐1249‐3p on HCC cell proliferation, colony formation, and invasion was examined by cell counting kit‐8 assay, colony formation assay, and transwell invasion assay, respectively. Luciferase activity reporter assay and western blot were performed to validate whether heterogeneous nuclear ribonucleoprotein K (HNRNPK) was a direct target of miR‐1249‐3p. Effect of miR‐1249‐3p on overall survival of HCC patients was analyzed at KM Plotter website.ResultsWe found miR‐1249‐3p expression level was increased, while HNRNPK expression level was decreased in HCC cell lines compared with normal cell line. Knockdown miR‐1249‐3p expression inhibits HCC cell proliferation, colony formation, and cell invasion through regulating HNRNPK in vitro. We also showed high miR‐1249‐3p expression was a predictor for poor overall survival of HCC patients.ConclusionsThese findings about miR‐1249‐3p/HNRNPK pair provide a novel therapeutic method for HCC patients.