bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supply chain management in Latin America: current research and future directions
Authors: Tanco Martin , Escuder Matias , Heckmann Gerardo , Jurburg Daniel , Velazquez Josue 
Published: October 2018

PurposeFor the past 20 years, Latin American countries have gone from being a low-cost region to significant players in the world economy, with five of its countries ranked among the world’s 50th largest by gross domestic product. This paper aims to study the contribution of Latin American researchers in the field of supply chain management (SCM) to aid an understanding of the Latin American impact within global supply chains (SCs).Design/methodology/approachThe authors present a study which includes a bibliometric analysis of the papers authored by Latin American researchers in the SCM field and which were exclusively published in journals included in the Journal Citation Reports. In addition, the authors conducted a survey to Latin American researchers and consultants to gain greater understanding of the main difficulties, which in their opinion, have negatively affected the SCM area in Latin America within the past five years, and identify possible misalignment between Latin American research and the challenges for SC in the region.FindingsThe results show that Latin American research on SCM in the past nine years is not significant for the field considering the number of papers, citations and the papers published in top journals. Another interesting finding is the lack of collaboration among researchers from different Latin American countries, as well as with corporate. Finally, survey results reveal significant differences regarding the main difficulties each country perceived as relevant.Practical implicationsComparing results from both analyses, relevant misalignments stand out between published research and the main difficulties detected. These suggest a challenging opportunity for Latin America, emphasizing the need to increase research contribution of the scientific community, through collaboration and alignment toward overcoming the most troublesome difficulties for Latin America. Therefore, the authors suggest future regional research directions which could also help global companies to tackle the challenges faced and optimize performance of their Latin American SCs.Originality/valueTo the best of the authors’ knowledge, no previous research on the quality and impact of Latin American research in SCM has been conducted. Also, misalignments between researchers and practitioners in the region, which allow identifying weaknesses of Latin American SCs, have not been studied before.
Maternal near‐miss and death among women with hypertensive disorders in pregnancy: a secondary analysis of the Nigeria Near‐miss and Maternal Death Survey
Authors: Adamu AN , Okusanya BO , Tukur J , Ashimi AO , Oguntayo OA , Tunau KA , Ekele BA , Oladapo OT 
Published: October 2018

ObjectiveTo investigate life‐threatening maternal complications related to hypertensive disorders of pregnancy (HDP) in Nigerian public tertiary hospitals.DesignSecondary analysis of a nationwide cross‐sectional study.SettingForty‐two tertiary hospitals.PopulationWomen admitted for pregnancy, childbirth or puerperal complications.MethodAll cases of severe maternal outcome (SMO: maternal near‐miss or maternal death) due to HDP were prospectively identified using the WHO criteria over a 1‐year period.Main outcome measuresIncidence of SMO, health service events, case fatality rate, and mortality index (% of maternal death/SMO).ResultsOut of 100 107 admissions for maternal complications, 6753 (6.8%) women had HDP. Pre‐eclampsia (PE) (54.5%) and eclampsia (E) (30.4%) were the most common HDP recorded. SMO occurred in 587 women with HDP: 298 maternal near‐misses and 289 maternal deaths. The majority (93%) of the women with SMO due to HDP were admitted in a critical condition. The median diagnosis–definitive intervention interval was over 4 hours in a quarter of women who died from HDP. For PE and E, case fatality rates were 1.9 and 10.4%, respectively, although both conditions had a similar mortality index of 49.3%. Lack of antenatal care and place of residence further than 5 km from the hospital were associated with maternal death.ConclusionsSevere maternal outcomes from HDP were due to late presentations and health system challenges. To reduce maternal deaths from HDP, health system strengthening that would engender early hospital presentation and prompt treatment is recommended.FundingThe original research that generated the data for this secondary analysis was funded by the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), a co‐sponsored programme executed by the World Health Organization (WHO). We have no other funding issue to declare for our study.Tweetable abstractEclampsia is the leading cause of maternal death in Nigerian hospitals.
Effects of organic acid and medium chain fatty acid blends on the performance of sows and their piglets
Authors: Lan Ruixia , Kim Inho 
Published: October 2018

AbstractThis study was aimed to evaluate the effects of organic acid (OA) and medium‐chain fatty acid (MCFA) blends on production performance of sows and their litters. A total of 36 sows (Landrace × Yorkshire, average parity is 3.3, SE = 0.2) were randomly allocated to three treatments with 12 replicates. Dietary treatments were as follows: CON, basal diet; MC1, CON + 0.1% OA, and MCFA blends; MC2, CON + 0.2% OA, and MCFA blends. During lactation, no differences were observed in body weight (BW) loss, average daily feed intake, backfat thickness, digestibility of dry matter, nitrogen, or energy of sows. There were linear increase (p < 0.05) in BW and average daily gain of sucking piglets. On parturition and weaning day, there was a linear increase (p < 0.05) in fecal Lactobacillus counts, as well as a linear decrease (p < 0.05) in fecal Escherichia coli counts of sows on weaning day. The sucking piglets also had a linear increase (p < 0.05) in fecal Lactobacillus counts and a linear decrease (p < 0.05) in fecal E. coli counts. In conclusion, dietary supplementation of OA and MCFA blends in sows exerts beneficial effects to sows shifted fecal microbiota by increasing Lactobacillus and decreased E. coli counts. It also improved the performance of piglets.
Hispaglabridin B, a constituent of liquorice identified by a bioinformatics and machine learning approach, relieves protein‐energy wasting by inhibiting forkhead box O1
Authors: Huang Zeng‐Yan , Wang Ling‐Jun , Wang Jia‐Jia , Feng Wen‐Jun , Yang Zhong‐Qi , Ni Shi‐Hao , Huang Yu‐Sheng , Li Huan , Yang Yi , Wang Ming‐Qing , Hu Rong , Wan Heng , Wen Chan‐Juan , Xian Shao‐Xiang , Lu Lu 
Published: October 2018

Background and PurposeLiquorice is the root of Glycyrrhiza glabra, which is a popular food in Europe and China that has previously shown benefits for skeletal fatigue and nutrient metabolism. However, the mechanism and active ingredients remain largely unclear. The aim of this study was to investigate the active ingredients of liquorice for muscle wasting and elucidate the underlying mechanisms.Experimental ApproachRNA‐Seq and bioinformatics analysis were applied to predict the main target of liquorice. A machine learning model and a docking tool were used to predict active ingredients. Isotope labelling experiments, immunostaining, Western blots, qRT‐PCR, ChIP‐PCR and luciferase reporters were utilized to test the pharmacological effects in vitro and in vivo. The reverse effects were verified through recombination‐based overexpression.Key ResultsThe liposoluble constituents of liquorice improved muscle wasting by inhibiting protein catabolism and fibre atrophy. We further identified FoxO1 as the target of liposoluble constituents of liquorice. In addition, hispaglabridin B (HB) was predicted as an inhibitor of FoxO1. Further studies determined that HB improved muscle wasting by inhibiting catabolism in vivo and in vitro. HB also markedly suppressed the transcriptional activity of FoxO1, with decreased expression of the muscle‐specific E3 ubiquitin ligases MuRF1 and Atrogin‐1.Conclusions and ImplicationsHB can serve as a novel natural food extract for preventing muscle wasting in chronic kidney disease and possibly other catabolic conditions.
Myocardial perfusion assessed with cardiac computed tomography in women without coronary heart disease
Authors: Bechsgaard Daria Frestad , Gustafsson Ida , Linde Jesper James , Kofoed Klaus Fuglsang , Prescott Eva , Hove Jens Dahlgaard 
Published: October 2018

SummaryPurposeCombined coronary CT angiography and CT perfusion (CTP) is a novel, non‐invasive, ‘one‐stop’ diagnostic tool to rule out ischaemia in patients suspected for coronary artery disease (CAD). However, the normal myocardial perfusion pattern by static CTP in humans is poorly described. We aimed to investigate global and regional myocardial perfusion during rest and adenosine‐induced hyperaemia in asymptomatic women without history of coronary heart disease (CHD).MethodsUsing a 320‐row CT scanner with a static protocol, semi‐quantitative assessment of rest and stress CTP was performed in 34 asymptomatic middle‐aged women without obstructive CAD (<50% stenosis) or history of CHD, and with normal exercise stress test and left ventricular (LV) function. Using a 16‐segment model, we assessed global and regional values of LV myocardial perfusion reserve (MPR) and transmural perfusion ratio (TPR).ResultsMean±SD age was 56 ± 13 years. Resting and hyperaemic myocardial perfusion was heterogeneously distributed throughout the LV myocardium. During hyperaemia, global MPR increased by median (IQR) 158% (144–176) with the highest increase in the right coronary artery territory (171%; P<0.02). Rest and stress segmental TPR values ranged between 0.93‐1.26 and 0.99‐1.13, respectively, with the lowest values detected in the inferoseptal segments. No differences in perfusion parameters were found between participants with normal epicardial arteries and participants with non‐significant epicardial atheromatosis (all P>0.05). Global perfusion parameters were not associated with age or menopausal status (all P>0.05).ConclusionsThis descriptive study presents data on global and regional myocardial perfusion in a cohort of healthy middle‐aged women.
Reliability and predictive validity of the Standardized Infant NeuroDevelopmental Assessment neurological scale
Authors: Hadders‐Algra Mijna , Tacke Uta , Pietz Joachim , Rupp André , Philippi Heike 
Published: October 2018

AimTo assess reliability and predictive validity of the neurological scale of the Standardized Infant NeuroDevelopmental Assessment (SINDA), a recently developed assessment for infants aged 6 weeks to 12 months.MethodTo assess reliability, three assessors independently rated video‐recorded neurological assessments of 24 infants twice. Item difficulty and discrimination were determined. To evaluate predictive validity, 181 infants (median gestational age 30wks [range 22–41wks]; 92 males, 89 females) attending a non‐academic outpatient clinic were assessed withSINDA's neurological scale (28 dichotomized items). Atypical neurodevelopmental outcome at 24 months or older corrected age implied a Bayley Mental Developmental Index or Psychomotor Developmental Index lower than 70 or a diagnosis of cerebral palsy (CP). Predictive values were calculated fromSINDA(2–12mo corrected age, median 3mo) and typical versus atypical outcome.ResultsIntraclass correlation coefficients of intrarater and interrater agreement of the neurological score varied between 0.923 and 0.965. Item difficulty and discrimination were satisfactory. At 24 months or older, 56 children (31%) had an atypical outcome (29 hadCP). Atypical neurological scores (below 25th centile, ≤21) predicted atypical outcome andCPwith sensitivities of 89% and 100%, and specificities of 94% and 81% respectively.InterpretationSINDA's neurological scale is reliable and in a non‐academic outpatient setting has a satisfactory predictive validity for atypical developmental outcome, includingCP, at 24 months or older.What this paper addsThe Standardized Infant NeuroDevelopmental Assessment's neurological scale has a good to excellent reliability.The scale has promising predictive validity for cerebral palsy.The scale has promising predictive validity for other types of atypical developmental outcome.
Predictors of virological failure in HIV‐1‐infected patients switching to dolutegravir maintenance monotherapy
Authors: Wijting IEA , Rutsaert SL , Rokx C , Burger DM , Verbon A , van Kampen JJA , Boucher CAB , Rijnders BJA , Vandekerckhove L 
Published: October 2018

ObjectivesThe Dolutegravir Monotherapy for HIV (DOMONO; NCT02401828) study showed that maintenance monotherapy with dolutegravir (DTG) is associated with virological failure (VF) and leads to DTG resistance and as a result should not be used. However, data on clinical and virological factors associated with VF during DTG monotherapy are lacking. We identified factors associated with VF during DTG monotherapy.MethodsA randomized trial was carried out in which patients on combination antiretroviral therapy (cART) with an HIV‐1 RNA zenith < 100 000 copies/mL and a CD4 T‐cell nadir ≥ 200 cells/μL, who had never experienced VF, switched to DTG monotherapy. Clinical and virological factors were compared between patients with and without VF, using univariate analyses.ResultsEight of the 95 patients developed VF during DTG monotherapy. A total of 78 participants had reached week 48 when the study was discontinued. The median CD4 T‐cell nadir was lower in patients with VF than in patients without VF [260 (interquartile range (IQR) 223–320) versus 380 (IQR 290–520) cells/μL, respectively; P = 0.011]. Patients with VF had a longer time between HIV diagnosis and cART initiation than those without VF [median 49 (IQR 27–64) versus 15 (IQR 1–38) months, respectively; P = 0.015]. The median total peripheral blood mononuclear cell (PBMC) HIV DNA copy number was higher in patients with VF than in those without VF [417 (range 85–4151) versus 147 (range 16–4132) copies/106 PBMCs, respectively; P = 0.022].ConclusionsA lower CD4 nadir, a longer time between HIV diagnosis and cART initiation, and a higher HIV DNA copy number at the time of DTG monotherapy initiation were associated with VF. While there clearly is no future role for DTG monotherapy, ongoing and future studies on the efficacy of maintenance dual therapy (e.g. DTG lamivudine) may have to take these variables into account in their study design and analysis.
Market Excess Returns, Variance and the Third Cumulant
Authors: Zhang Jin E. , Chang Eric C. , Zhao Huimin 
Published: October 2018

AbstractIn this paper, we develop an equilibrium asset pricing model for market excess returns, variance and the third cumulant by using a jump‐diffusion process with stochastic variance and jump intensity in Cox et al. (1985) production economy. Empirical evidence with the S&P 500 index and options from January, 1996 to December, 2005 strongly supports our model prediction that the lower the third cumulant, the higher the market excess returns. Consistent with existing literature, the theoretical mean–variance relation is supported only by regressions on risk‐neutral variance. We further demonstrate empirically that the third cumulant explains significantly the variance risk premium.
Contracting Sequentially with Multiple Lenders: The Role of Menus
Authors: ATTAR ANDREA , CASAMATTA CATHERINE , CHASSAGNON ARNOLD , DÉCAMPS JEAN PAUL 
Published: October 2018

AbstractWe study a credit market in which multiple lenders sequentially offer financing to a single borrower under moral hazard. We show that restricting lenders to post single offers involves a loss of generality: none of the equilibrium outcomes arising in this scenario survives if lenders offer menus of contracts. This result challenges the approach followed in standard models of multiple lending. From a theoretical perspective, we offer new insights on equilibrium robustness in sequential common agency games.
A Tale of Two Growth Engines: Interactive Effects of Monetary Policy and Intellectual Property Rights
Authors: CHU ANGUS C. , LAI CHING‐CHONG , LIAO CHIH‐HSING 
Published: October 2018

AbstractHow do intellectual property rights that determine the market power of firms influence the growth and welfare effects of monetary policy? To analyze this question, we develop a monetary hybrid endogenous growth model in which R&D and capital accumulation are both engines of long‐run economic growth. We find that monetary expansion hurts economic growth and social welfare by reducing R&D and capital accumulation. Furthermore, a larger market power of firms strengthens these growth and welfare effects of monetary policy through the R&D channel but weakens these effects through the capital‐accumulation channel. Therefore, whether the market power of firms amplifies or mitigates the welfare cost of inflation depends on the relative importance of the two growth engines. Finally, we calibrate the model using data in the United States and the Euro Area to quantitatively evaluate and compare the welfare cost of inflation in these two economies and find that the R&D channel dominates in both economies.
Validation of the Nursing Diagnosis “Labile Emotional Control” in Traumatic Brain Injury
Authors: Santos Ana Carla Ferreira Silva dos , Hora Mota Edilene Curvelo , Santos Valmira dos , Cartaxo Freitas Carla Kalline Alves , Barreiro Maria do Socorro Claudino , Santos Lyvia de Jesus Andrade dos , de Andrade Joseilze Santos , Vasconcelos Geferson Messias Teles , Freitas João Paulo Almeida 
Published: October 2018

AbstractObjectiveTo validate the defining characteristics of the nursing diagnosis “labile emotional control” in traumatic brain injury (TBI) outpatients.DesignThis was a descriptive, cross‐sectional, quantitative study.MethodsThirty‐one Brazilian nurses who were experts in the area of TBI answered a semistructured questionnaire on the diagnosis “labile emotional control” based on NANDA‐International (NANDA‐I) Taxonomy II (2015–2017) using a Likert‐type scale to rate the 13 defining characteristics. Based on Fehring's model, the weighted average of ≥80 was used to define the main characteristic and the mean of ≥0.50 was considered for total content validation.ResultsOut of the 13 defining characteristics of the nursing diagnosis studied, “leaving a social situation” (0.80) and “expression of emotions inconsistent with the triggering factor” (0.81) were classified as principal characteristics, while the 11 others were classified as secondary characteristics. The diagnosis “labile emotional control” obtained a total score of 0.69, which was considered valid according to NANDA‐I Taxonomy II.ConclusionsBecause this is a new diagnosis with subjective characteristics, there is a need to train nurses to recognize the defining characteristics for the diagnosis.Clinical RelevanceThe validation of this diagnosis helps nurses understand and identify the subjective characteristics of the emotional impressions expressed by patients with TBI. These defining characteristics will help improve TBI nurses’ clinical practice.
Pseudo‐nitzschia nanaoensis sp. nov. (Bacillariophyceae) from the Chinese coast of the South China Sea
Authors: Li Yang , Dong Huan Chang , Teng Sing Tung , Bates Stephen S. , Lim Po Teen 
Published: October 2018

Pseudo‐nitzschia nanaoensis sp. nov. is described from waters around Nan'ao Island (South China Sea), using morphological data and molecular evidence. This species is morphologically most similar to P. brasiliana, but differs by a denser arrangement of fibulae, interstriae, and poroids, as well as by the structure of the valvocopula and the narrow second band. Pseudo‐nitzschia nanaoensis constitutes a monophyletic lineage and is well differentiated from other species on the LSU and ITS2 sequence‐structure trees. Pseudo‐nitzschia nanaoensis makes up the basal node on the LSU tree, and forms a sister clade with a group of P. pungens and P. multiseries on the ITS2 tree. The ability of cultured strains to produce domoic acid was assessed, including its possible induction by the presence of a copepod and brine shrimp, by liquid chromatography–tandem mass spectrometry. However, no strains showed detectable domoic acid.
First record of dwarf Victorian mouthbrooder Pseudocrenilabrus multicolor victoriae (Schöller, 1903) in Lake Naivasha, Kenya, including data on its molecular identification: Management implications
Authors: Otachi Elick O. , Rindoria Nehemiah M. , Medhanit Meri M. , Ayeka Peter A. , Wąs‐Barcz Anna 
Published: October 2018

AbstractThe present study describes the first record of 83 Dwarf Victorian mouthbrooder (Pseudocrenilabrus multicolor victoriae Seegers, 2000) newly discovered in Lake Naivasha, Kenya, in January 2016. Membership of the species was determined on the basis of morphometric characteristics and molecular analysis. The average length (±SD) of the fish was 6.95 ± 0.86 cm, and average weight was 5.59 ± 1.99 g. The body is normal/fusiform, the dorsal head profile convex‐shaped, the mouth is terminal with bright blue lips, and the anal fin with a reddish tip, being distinctive features of the fish. The sequences of subunit I cytochrome oxidase (COI) and cytochrome b (cyt b) genes obtained in the present study were compared with records deposited in BoldSystem and NCBI databases. Using two genetic markers enabled unambiguous determination of the species membership. The queried specimen was assigned to the Cichlidae family, as Pseudocrenilabrus multicolor victoriae (100–96.68% similarity). These results constitute the baseline study for this fish in Lake Naivasha.
Making anthropology relevant: Collaborative assessment in support of graduate and undergraduate success beyond the university
Authors: RICKE AUDREY 
Published: October 2018

AbstractWhile team‐based and interdisciplinary research is increasingly common for anthropologists and other researchers, pedagogical strategies for integrating hands‐on training in this area is underexplored. As anthropologists reflect on how to prepare the next generation of researchers, this article addresses a strategy for designing and assessing undergraduate assignments that provides undergraduate and graduate students experiences that are transferable to interdisciplinary and team‐based projects. I argue that a collaborative assessment approach to undergraduate applied anthropology assignments based on a model for developing team‐based codebooks by MacQueen et al. (2008) can support graduate and undergraduate students in acquiring skills for their future careers. Drawing on several years of experience teaching medium‐to‐large enrolling introductory cultural anthropology courses, this article illustrates how a collaborative assessment approach offers graduate teaching assistants hands‐on experience with navigating team‐based projects and codebook development as well as supports undergraduate students in refining their critical thinking and writing skills interdisciplinarily.
China’s rise, asymmetric trade shocks and exchange rate regimes
Authors: Caselli Francesca G. 
Published: October 2018

AbstractChina’s rapid growth provides a natural experiment to study the effects of asymmetric trade shocks on the competitiveness of OECD countries. The different levels of exposure to Chinese trade competition, as measured using an index of export similarity, triggered asymmetric shocks as China’s trade surged. Motivated by a Ricardian framework, this paper finds that countries with exports similar to those of China experience a loss in competitiveness compared with countries with a different trade structure. Once an additional layer of distinction is introduced between fixed and flexible exchange rate regimes, I find that countries with a fixed exchange rate and with relatively high similarity to China experience a real appreciation.