bluuebunny/crossref_metadata_2025_split huggingface dataset:
Socioeconomic Determinants of Inequalities in the Use of Modern Contraception among Currently Married Women
Authors: Pokhrel Taranath , Aryal Kabita , Adhikari Ramesh , Dulal Bishnu Prasad , Karki Deepak Kumar , Dahal Harsha Raj , Dangol Milima Singh , Poudel Pradeep , Bhattarai Navaraj , Lamichhane Prabhat 
Published: November 2024

Background: Despite interventions for over four decades, the unmet need for family planning is high in Nepal. This study aims to examine the status and the socioeconomic determinants of inequalities in modern contraception among currently married women.Methods: We applied a mixed-method design. We interviewed key informants for qualitative information and analyzed secondary data from the Nepal Multiple Indicator Cluster Survey, 2019, and different rounds of Nepal Demographic and Health Surveys. We calculated ratios, differences in percentages, and concentration indices to analyse the inequality. We ran a binary logistic regression model to estimate the adjusted effect of each factor on the use of modern contraception. Results: The richest-to-poorest difference in using modern contraception has decreased over 13 years. The richest-to-poorest difference decreased from 23.6 percentage points in 2006 to 13.3 percentage points in 2011 and further to 1.2 percentage points in 2016. The richest-to-poorest difference was negative in 2019, indicating poor people are using more contraception than the richest. Multivariate analysis showed the wealth is a significant predictor for using contraception. Women of richer households (aOR=1.29, 95% CI=1.13-1.48), middle (aOR=1.21, 95% CI=1.05-1.40), poorer (aOR=1.36, 95% CI 1.17-1.58) and poorest (aOR=1.18, 95% CI=1.05-1.34) were more likely to use contraception than women from the richest households. Conclusions: Poor people are increasingly using the modern contraception, and the gap between the poor and rich people has decreased. However, the trend of contraception use in each wealth quintile indicates that Nepal struggles to meet the sustainable development goal target of reducing the unmet need for family planning to less than 10% by 2030.Keywords: Contraception; inequalities; married women; nepal; wealth status.
Detection of Colonic Polyps During Colonoscopy in a Tertiary Care Center of Nepal
Authors: Koirala Dinesh , Pathak Rahul , Kafle Bhandari Brindeswari , Jha Anurag , Hamal Rabin , Gnawali Arun , Pandey Rajesh , Bhusal Mohan 
Published: November 2024

Background: Colorectal cancer is the third leading cause of cancer death in the world. Most colon cancer develop from the polyps. Data on the prevalence of colorectal polyps in Nepal is lacking. The objective was to determine the prevalence of colorectal polyps, site of occurrence and adenomas among various age groups. All polyps after removal by polypectomy was sent for histopathological examination.Methods: Study was done in 1027 consecutive patients who underwent colonoscopy in the pre-specified time after excluding patients with colorectal cancer, Inflammatory Bowel Disease and polyposis syndromes. Results: Among 1027 patients, the mean age was 45 years. 292 (28.43%) were below 40 years, whereas, 735 (71.57%) were above 40 years. Polyps were detected in 12.95% of overall patients and in 9.73% of patients over age 40. The most common location of polyps was rectum (46.62%). 43.61% were adenomatous polyps, 11.28% were hyperplastic polyps, 18.05% were juvenile polyps, 22.56% were inflammatory polyps and 1.50% were malignant adenocarcinoma. Polyp detection rate was 12.95%, whereas adenoma detection rate was 5.84%. 46.55% had advanced adenomas. A positive correlation between the size of polyp and adenomatous variety was found [Chi-square value ?2 = 8.42 (>3.841), p value <0.05]. Prevalence of adenomatous polyps was significantly higher above the age of 40 [Chi-square value ?2 = 11.53 (>3.841), p value<0.05]. Conclusions: The prevalence of polyp increases with age. With increasing age and size of polyp, the prevalence of adenomatous polyp increases significantly. One out of every eight people over 40 years had a colonic polyp.Keywords: Colorectal cancer; colonoscopy; colonic polyp; screening
Overcoming cultural taboo: A qualitative study of the untold lived experience of older adults’ sexual life in Cebu, Philippines
Authors: Sta. Teresa Marjorie R. , Ragay Alain Kenneth S. , Machacon Alberich F. 
Published: November 2024

Background: The craving for sexuality and closeness continues into old age, although the means of expressing it may change. Beyond direct sexual encounters, older adults can express their sexuality through gentle affection, warm embraces, holding hands, and other intimate gestures. However, aging can also impact their sexual experiences.
Objective: This study aimed to explore the lived experiences of sexuality among older adults living in the countryside of Cebu, Philippines, during their senior years.
Methods: A qualitative descriptive phenomenological design was employed. Purposive sampling was used to select ten participants. Data were collected from September to December 2023, and Colaizzi’s method of data analysis was applied to ensure thorough interpretation.
Results: Three major themes emerged: 1) Being Centered: An actualized form of sexuality in later years; 2) Being Connected: A strong sense of intimacy in later years; and 3) Being Conveyed: Diversifying expressions of sexuality in later years.
Conclusion: Despite advancing age, older adults can remain active in their intimate relationships and achieve a healthy marital life characterized by life satisfaction. They express their love for their partners by being centered, connected, and attuned to each other’s needs and feelings. These findings highlight the importance for geriatric nurses to recognize and support the sexual health and intimacy needs of older adults, facilitating discussions and providing resources that promote overall well-being and quality of life.
Lower accuracy of estimated delivery date using last menstrual period recall and related factors of adverse events during childbirth: A sub-analysis of a birth cohort study in Makassar, Indonesia
Authors: Wijaya Eri , Ansariadi  , Hadju Veni , Sjahril Rizalinda , Adisasmita Asri C , Mallongi Anwar , Stang  
Published: November 2024

Background: Early pregnancy ultrasound provides a more accurate estimate of the estimated delivery date (EDD) than the last menstrual period (LMP). However, LMP-based EDD calculation remains common in resource-limited settings. Inaccurate EDDs can contribute to adverse birth outcomes. However, research examining the accuracy of LMP-based EDDs and their association with delivery-related adverse events is limited.
Objective: This study aimed to evaluate the accuracy of self-reported LMP in predicting EDD and its association with adverse events during delivery.
Methods: Data were analyzed from 171 pregnant women participating in the Indonesian Birth Cohort Study based in Makassar, Indonesia. This study utilized a prospective cohort design, employing descriptive statistics and Poisson regression analysis in Stata. Adverse events were defined as any unexpected negative occurrence during delivery, including issues related to healthcare access, birth attendance, and the medical condition of the mother and newborn.
Results: Mode of delivery and categorized differences between actual delivery date and estimated delivery date (ADD-EDD) were significantly associated with adverse events during delivery. Cesarean delivery was associated with a higher risk of adverse events compared to vaginal birth (Adjusted Risk Ratio [ARR] 1.11, 95% CI: 1.02–1.22, p <0.001). Additionally, ADD-EDD differences of ≤-15 days (ARR 1.49, 95% CI: 1.35–1.65), -14 to -8 days (ARR 1.33, 95% CI: 1.19–1.49), and ≥15 days (ARR 1.37, 95% CI: 1.20–1.58) showed an increased risk (all p <0.001). An ADD-EDD difference of 8 to 14 days was marginally significant (ARR 1.20, 95% CI: 1.00–1.44, p = 0.046). The ADD-EDD distribution showed notable gaps, with ADD deviations occurring as early as 109 days before and as late as 45 days after the EDD. On average, the ADD occurred approximately one week earlier (-7.15 days) than the EDD.
Conclusion: Lower accuracy of LMP-based EDDs and delivery mode is associated with increased adverse events during delivery. Transitioning from LMP-based EDDs to more accurate methods is necessary to improve maternal and neonatal care outcomes. Integrating routine early ultrasound for EDD calculation can better equip healthcare providers and nurses to plan deliveries, reduce risks, and improve patient outcomes in resource-limited settings.
Kepuasan Kerja Sebagai Penguat Loyalitas Kerja Pegawai dalam Kerangka Kesehatan Sosial di Sekolah
Authors: Abidin Faris , Kattari Raisah Putri 
Published: November 2024

<p align="center"><em>Work loyalty is one of the elements used in employee assessment which includes loyalty to work, position and organization. Job satisfaction is one of the factors that can influence employee loyalty in working. This study aimed to analyze the relationship between job satisfaction and employee work loyalty in Senior High Schools in Mataram City. This study involved 54 employees working in Senior High Schools in Mataram City, who were selected using consecutive sampling techniques. The focus of the study was job satisfaction and loyalty, which were measured by filling out a questionnaire. The data were then analyzed using the Pearson correlation test. The results showed that the correlation coefficient between job satisfaction and work loyalty was 0.573, while the p value was 0.000; so it could be interpreted that there was a positive correlation between job satisfaction and employee work loyalty. Furthermore, it was concluded that job satisfaction is a reinforcement for work loyalty.</em></p><p><strong><em>Keywords</em></strong><em>: social health; work loyalty; job satisfaction; employees</em></p><p> </p><p align="center"><strong>ABSTRAK</strong></p><p> </p><p>Loyalitas kerja merupakan salah satu unsur yang digunakan dalam penilaian karyawan yang mencakup kesetiaan terhadap pekerjaan, jabatan dan organisasi. Kepuasan kerja merupakan salah satu faktor yang dapat mempengaruhi loyalitas karyawan dalam bekerja. Penelitian ini bertujuan untuk menganalisis hubungan antara kepuasan kerja dan loyalitas kerja pegawai di Sekolah Menengah Atas Kota Mataram. Penelitian ini melibatkan 54 pegawai yang bekerja di Sekolah Menengah Atas Kota Mataram, yang dipilih dengan teknik <em>consequtive sampling</em>. Fokus penelitian adalah kepuasan kerja dan loyalitas, yang diukur melalui pengisian kuesioner. Data kemudian dianalisis menggunakan uji korelasi Pearson. Hasil penelitian menunjukkan bahwa koefisien korelasi antara kepuasan kerja dengan loyalitas kerja adalah 0,573, sedangkan nilai p adalah 0,000; sehingga bisa diinterpretasikan bahwa ada korelasi positif antara kepuasan kerja dan loyalitas kerja karyawan. Selanjutnya disimpulkan bahwa kepuasan kerja merupakan penguat bagi loyalitas kerja.</p><strong>Kata kunci</strong>: kesehatan sosial; loyalitas kerja; kepuasan kerja; pegawai
Diabetes Self Management, Usia, HbA1c dan Lama Menderita Terbukti Berdampak pada Fungsi Seksual
Authors: Puspitasari Widya , Irawati Diana , Untari Dyah 
Published: November 2024

<p align="center"><em>Diabetes mellitus as a metabolic disease that causes increased blood glucose levels, has an impact on sexual dysfunction in men and women. Sexual dysfunction can be prevented with proper diabetes self-management. The purpose of this study was to analyze the effect of diabetes self-management, age, HbA1c, duration of diabetes mellitus and mental health on sexual function of patients. This study was conducted at the dr. Chasbullah Abdulmadjid Hospital in Bekasi City, by implementing a cross-sectional design. The sample was 148 patients with diabetes mellitus selected using the consecutive sampling method. The specific measuring instruments used in measuring the variables were DSMI, FSFI and IIEF. The results of the analysis showed that the p value for each factor was diabetes self-management = 0.001, age = 0.046, HbA1c = 0.023; duration of diabetes mellitus = 0.038 and mental health = 0.298. Thus it can be concluded that the factors that affect the sexual function of patients with diabetes mellitus are diabetes self-management, age, HbA1c and duration of diabetes mellitus.</em></p><p><strong><em>Keywords</em></strong><em>: diabetes mellitus; sexual function; self management; age; HbA1c; duration of diabetes; mental health</em></p><p><strong><em> </em></strong></p><p align="center"><strong>ABSTRAK</strong></p><p><strong><em> </em></strong></p><p>Diabetes mellitus sebagai penyakit metabolik yang mengakibatkan peningkatan kadar glukosa darah, berdampak pada gangguan fungsi seksual pada pria dan wanita. Gangguan fungsi seksual dapat dicegah dengan <em>diabetes</em> <em>self management</em> yang tepat. Tujuan dari penelitian ini adalah menganalisis pengaruh <em>diabetes</em> <em>self management</em>, usia, HbA1c, lama menderita diabetes mellitus dan kondisi kejiwaan terhadap fungsi seksual penderita. Studi ini dilaksanakan di RSUD dr Chasbullah Abdulmadjid Kota Bekasi, dengan menerapkan rancangan <em>cross-sectional. </em>Sampel adalah 148 penderita diabetes<em> </em>mellitus yang dipilih menggunakan metode <em>consecutive sampling</em>. Alat ukur khusus yang digunakan dalam pengukuran variabel adalah DSMI, FSFI dan IIEF. Hasil analisis menunjukkan bahwa nilai p untuk masing-masing faktor adalah <em>diabetes</em> <em>self management </em>= 0,001, usia = 0,046, HbA1c = 0,023; lama menderita diabetes mellitus = 0,038 dan kondisi kejiwaan = 0,298. Dengan demikian bisa disimpulkan bahwa faktor yang berdampak pada fungsi seksual penderita diabetes mellitus adalah <em>diabetes</em> <em>self management</em>, usia, HbA1c dan lama menderita diabetes mellitus.</p><p><strong>Kata kunci:</strong> diabetes mellitus; fungsi seksual; <em>self management; </em>usia; HbA1c;<em> </em>lama menderita diabetes;<em> </em>kejiwaan</p><p><strong><em> </em></strong></p>
Virgin Coconut Oil (VCO) Terbukti Efektif untuk Menurunkan Derajat Diapers Rash pada Bayi
Authors: Sofyan Evi , Purwati Nyimas Heny , Apriliawati Anita , Pramono Prastowo Sidi 
Published: November 2024

<p> <em>Skin disorders that often occur in infants include atopic dermatitis, seborrhea, boils, miliariasis, allergies, and inflammation in the form of skin rashes known as diaper rash. One nursing intervention that can be done is the use of virgin coconut oil. This study aimed to test the effectiveness of virgin coconut oil to reduce the degree of diaper rash in infants. This study applied a pretest and posttest with control group design. The sample was selected using a purposive sampling technique so that 36 respondents were divided into the treatment group and the control group. Diaper rash was measured through observation using the New DDS, then the data obtained were analyzed using a paired samples t-test. The results of the analysis showed that the p value for the control group and the treatment group were each less than 0.05, but there was a greater decrease in the treatment group. Based on the results of the study, it was concluded that virgin coconut oil is effective in reducing the degree of diaper rash and can be an independent nursing intervention.</em></p><p><strong><em>Keywords</em></strong><em>: diapers rash; virgin coconut oil; infants</em></p><p> </p><p align="center"><strong>ABSTRAK</strong></p><p> </p><p>Gangguan kulit yang sering timbul pada bayi antara lain dermatitis atopik, seborrhea, bisul, miliariasis, alergi, dan peradangan berupa ruam kulit yang dikenal dengan <em>diapers rash</em>. Salah satu intervensi keperawatan yang bisa dilakukan yaitu penggunaan <em>virgin coconut oil</em>. Penelitian ini bertujuan untuk menguji efektivitas <em>virgin coconut oil</em> untuk menurunkan derajat <em>diapers rash</em> pada bayi. Penelitian ini menerapkan rancangan <em>pretest and posttest with control group</em>. Sampel dipilih dengan teknik <em>purposive sampling </em>sehingga didapatkan 36 responden yang di bagi kelompok perlakuan dan kelompok kontrol. <em>Diaper rash</em> diukur melalui observasi menggunakan <em>New DDS</em>, lalu data yang diperoleh dianalisis menggunakan <em>paired samples t-test</em>. Hasil analisis menunjukkan bahwa nilai p untuk kelompok kontrol maupun kelompok perlakuan masing-masing adalah kurang dari 0,05, namun terjadi penurunan lebih banyak pada kelompok perlakuan. Berdasarkan hasil penelitian disimpulkan bahwa <em>virgin coconut oil</em> efektif untuk menurunkan derajat <em>diapers rash</em> dan bisa menjadi intervensi mandiri keperawatan.</p><p><strong>Kata kunci:</strong> <em>diapers rash;</em> <em>virgin coconut oil</em>; bayi</p>
Cytotoxicity of natural and synthetic cannabinoids and their synergistic antiproliferative effects with cisplatin in human ovarian cancer cells
Authors: Chen Ying , Li Huifang , Liu Jia , Ni Jie , Deng Qicheng , He Haotian , Wu Panpan , Wan Yinsheng , Seeram Navindra P. , Liu Chang , Ma Hang , Zhu Weipei 
Published: November 2024

IntroductionCannabinoids are reported to suppress the growth of ovarian cancer cells, but it is unclear whether structural modifications can improve their cytotoxic effects.MethodsHerein, an investigation into the antiproliferative effects of natural cannabinoids on human ovarian cancer Caov-3 cells identified cannabidiol (CBD) as the most promising cannabinoid. Furthermore, chemical modifications of CBD yielded a group of derivatives with enhanced cytotoxicity in Caov-3 cells.ResultsTwo CBD piperazinyl derivatives (19 and 21) showed augmented antiproliferative effects with an IC50 of 5.5 and 4.1 µM, respectively, compared to CBD’s IC50 of 22.9 µM. Further studies suggest that modulation of apoptosis and ferroptosis may contribute to the cytotoxic effects of CBD and its derivatives. In addition, CBD and its derivatives (19 and 21) were explored for their potential synergistic antiproliferative effects in combination with chemotherapeutic agent cisplatin. Compounds 19 or 21 (5 µM) combined with cisplatin (1 µM) showed a synergistic effect with a combination index of 0.23 and 0.72, respectively. This effect was supported by elevated levels of reactive oxygen species in Caov-3 cells treated with cisplatin combined with 19 or 21.DiscussionFindings from this study suggest that CBD derivatives with enhanced antiproliferative effects may exert synergistic effects with chemotherapeutic drugs, providing insight into the development of cannabinoid-based adjuvant agents for the management of ovarian cancer.
Sinais e sintomas relacionados ao climatério: análise de uma população atendida em um hospital de ensino da zona da Mata Mineira
Authors: Couri Ana Beatriz Baldanza Rodrigues Raymundo , Fiche Ana Clara Netto Armando , Pinheiro Leonardo Sotto Maior do Valle , Figueiredo Ana Cláudia Dias de Sousa 
Published: November 2024

Introdução: A transição entre o estágio reprodutivo e o não reprodutivo é denominada climatério. O envelhecimento leva à falência ovariana progressiva, determinando a interrupção dos ciclos ovulatórios e a parada do sangramento menstrual. Durante esse período, surgem alterações no sistema vasomotor, neuropsíquico e urogenital, afetando a qualidade de vida da mulher. Objetivo: Identificar a ocorrência de sinais e sintomas nas mulheres no climatério que frequentam o ambulatório de um hospital de ensino. Métodos: Este estudo observacional incluiu 104 mulheres entre 40 a 65 anos, atendidas em um hospital de ensino na cidade de Juiz de Fora-MG. Após explicação e assinatura do TCLE, as pacientes receberam dois questionários impressos, um de identificação e o MRS (Menopause Rating Scale), cujas respostas foram registradas para análise. Resultados: A faixa etária média das participantes foi de 51.875 anos, e 72.12% delas possuía companheiro fixo. Os sintomas mais comuns foram esgotamento físico e mental (82/104); ansiedade (81/104); falta de ar, suores, calores (80/104); irritabilidade (75/104); problemas musculares e das articulações (75/104). De maneira geral e concordante a outros estudos, os sintomas de climatério tendem a aumentar em incidência e severidade conforme o avançar de idade, com forte correlação entre sintomas neuropsíquicos. Conclusão: Os dados encontrados reforçam a importância de cuidados contínuos e individualizados para melhorar a qualidade de vida das mulheres durante o climatério, dado o impacto significativo dessa fase em sua saúde.
Perfil epidemiológico: análise das internações hospitalares por glaucoma no Espírito Santo no período de 2013 a 2022
Authors: Soares Luise Schwan , Moussallem Lara Bunjes , Miranda Gabriely Miliorini de , Ferraz Marcela Gomes , Queiroz Gradiva Antônia Gonçalves de Barros Silveira de , Pansini Karielly Gasperazzo , Soares Fábio Braga 
Published: November 2024

Introdução: O glaucoma, neuropatia óptica progressiva, é a principal causa de cegueira irreversível em aspecto mundial e no Brasil. Torna-se fundamental traçar um perfil epidemiológico a fim de corroborar com dados capazes de auxiliar na prevenção dessa doença. Objetivo: Identificar o perfil de internações hospitalares por glaucoma no Espírito Santo de 2013 até 2022. Método: Estudo transversal observacional de agregado temporal com dados obtidos no Departamento de Informática do Sistema Único de Saúde do Brasil (DATASUS) - Sistema de Informações Hospitalares do SUS (SIH/SIS). Foram coletadas informações dos pacientes internados por glaucoma no estado do Espírito Santo (ES) de janeiro de 2013 até dezembro de 2022. Resultados e Discussão: Os anos com maior número de internações por glaucoma no ES foram 2015, 2016 e 2017 com 22, 24, 23 casos respectivamente. O caráter dessas internações se divide em 69,6% eletivos e 30,4% nas urgências, o que pode ser explicado pelo maior número de casos de glaucoma de ângulo aberto em contraponto com os casos de urgência no glaucoma de ângulo fechado. Observou-se um pico bimodal entre as idades, com maior prevalência em crianças <4 anos (31 internações), e adultos entre 50-69 anos (44 internações). A cor/raça branca apresentou 46,4% das internações por glaucoma, discordando da literatura e demonstrando a importância de outros fatores de risco. Conclusão: Destaca-se a necessidade de atenção contínua à gestão do glaucoma, fornecendo um sólido ponto de partida para a formulação de políticas de saúde direcionadas à assistência oftalmológica no ES.