bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between Uric Acid with Thyroid Disorders of Diabetic Patients in Iraq
Authors: Falih Israa , Tahir Noor , Taha Nada Razooqe , Al-Auqbi Tawfeeq F. R. 
Published: December 2024

Uric acid is the product of purine metabolism. its raised can lead to complications associated with metabolic diseases. We seek to shed light on the association between thyroid disorders in diabetes and hyperuricemia. The aim of this study is to demonstrate the association of uric acid with diabetes and its chronic complications through aspects of pathogenesis and clinical research Anthropometric, clinical, and hormonal measurements. patients (140) were divided into three groups. Sixty T2DM with euthyroidism (G1), fifty T2DM with hypothyroidism (G2), and Thirty T2DM with hyperthyroidism (G3). A high significant correlation (P < 0.01, P= 1) between uric acid Vs. G1, G2, and G3 groups. Uric acid significantly differed at (P< 0.05) between (G1 Vs. G2), and (G1 Vs. G3) .A negative correlation between uric acid and thyroids hormones at G1, G2, and G3 groups. The study showed the effect of uric acid through the correlation coefficient for both clinical and hormonal indicators in diabetic patients with thyroid dysfunction.
TOXICITY OF THE HERBICIDE 2, 4-D DIMETHYL AMINE SALT ON BEHAVIORAL, HISTOLOGICAL AND OXIDATIVE STRESS BIOMARKERS OF AFRICAN CATFISH CLARIAS GARIEPINUS (BURCHELL, 1822) FINGERLINGS
Authors: Hamisu Y. , Auta J. , Bawa Bolanle S. 
Published: December 2024

The aim of this paper was to assess the toxicological impacts of the Herbicide 2, 4-D Dimethyl amine salt on Clarias gariepinus fingerlings. The fishes were exposed to lethal concentration of 0.00, 1.34, 1.42, 1.48, 1.54 and 1.60ml/L for 96 hours as well as sub-lethal concentrations of 0.00, 0.069, 0.138 and 0.276ml/l of 2, 4-D Dimethyl amine salt for 8 weeks. The value of 96 hours LC50 was 1.385ml/L. Respiratory disturbance, loss of equilibrium, and sudden fish death were observed in 96hrs of exposed fish, and these varied greatly with increase in concentration of the toxicant, with a trend of significant (p<0.05) increase in mortality with increasing concentrations. As the concentration of 2, 4-D dimethyl amine salt increased the beats of the tail and opercular ventilation increased at 12 and 24 but decreased at 72 and 96 hours. The lethal exposure of Clarias gariepinus fingerlings to 2, 4-D dimethyl amine salt indicate significant changes in enzymes activity of liver for SOD and CAT. at 1.36, 1.42, 1.48, 1.54 and 1.6ml/L while sub-lethal show no significant changes. The changes for lethal and sub-lethal in gills were characterized by, inflammation of primary and secondary lamella, vacuolation, filament atropy. The liver showed, necrosis, adipocyte infiltration, and lymphocyte hyperplasia in fish exposed lethal and sub lethal concentrations of 2, 4-D Dimethyl amine salt.
Optimalisasi Jurnal Mahasiswa: Inisiatif Pelatihan dalam Memulai dan Mengelola Jurnal Ilmiah
Authors: Anggraini Melaty , Rachmawati Iva 
Published: December 2024

Penelitian ini membahas inisiatif pelatihan untuk mahasiswa dalam memulai dan mengelola jurnal akademik. Fokus utamanya adalah pada peningkatan pemahaman dan keterampilan mahasiswa dalam mengelola proses publikasi jurnal ilmiah. Pelatihan ini dirancang untuk memberikan wawasan tentang langkah-langkah awal dalam memulai jurnal mahasiswa, termasuk pemilihan topik, perencanaan konten, dan struktur artikel. Selain itu, pelatihan juga memberikan panduan praktis tentang pengelolaan jurnal secara efisien menggunakan platform online, seperti Open Journal Systems (OJS). Metode pelatihan melibatkan workshop interaktif, diskusi kelompok, dan sesi praktik langsung untuk mendorong partisipasi aktif dan pemahaman yang mendalam bagi mahasiswa jurusan ilmu hubungan internasional UPNâ€Veteranâ€Yogyakarta, dan Universitas Mitra pengabdian yaitu Universitas Sebelas Maret. Evaluasi efektivitas pelatihan dilakukan melalui survei prapostes dan survei pascapostes untuk mengukur peningkatan pengetahuan dan keterampilan mahasiswa. Hasil penelitian menunjukkan bahwa pelatihan ini berhasil meningkatkan pemahaman dan keterampilan mahasiswa dalam memulai dan mengelola jurnal akademik. Implikasinya, pelatihan semacam ini dapat menjadi landasan yang kuat untuk mengembangkan kultur publikasi ilmiah di kalangan mahasiswa serta meningkatkan kontribusi mereka dalam dunia akademik.

Keywords: Academic Writing, Publikasi Ilmiah, Jurnal Mahasiswa.
Contribuições do Museu da Natureza, Piauí, Brasil, para a formação de educadores do campo
Authors: Leite dos Santos Silva Alexandre , Machado dos Reis Flávia , Gomes Lopes Suzana , Gimenez Pinheiro Tamaris 
Published: December 2024

Os museus de ciências podem contribuir de forma singular para a formação inicial e continuada de professores. Neste trabalho, destaca-se o Museu da Natureza, inaugurado em 2018 pela Fundação do Museu do Homem Americano e localizado ao lado do Parque Nacional da Serra da Capivara, no município piauiense Coronel José Dias. O objetivo deste artigo é apresentar os resultados de uma pesquisa sobre as contribuições do Museu da Natureza na formação de educadores do campo. Ocorreu no âmbito do tempo comunidade da disciplina Geociências do Curso de Licenciatura em Educação do Campo, na Universidade Federal do Piauí. Na metodologia, foi realizada a Análise Temática dos relatórios de visita de 29 licenciandos. Os resultados mostraram que a visita ao referido museu contribuiu para proporcionar a aprendizagem prática, sinestésica e estimulante, com potencialidades para a sala de aula; com vistas a promover a educação contextualizada e para estimular o pensamento crítico, com destaque para a educação ambiental.
Palavras-chave: educação museal. Educação no campo. Ensino de Ciências.
Perspectivas Educacionais na Sociedade Globalizada
Authors: Vasel Carmen , Bispo Milhomens Raphael 
Published: December 2024

Este trabalho apresentou argumentos e experiência de ensino a partir dos Caminhos Educacionais na era globalizada. Para tanto, utilizou textos analisados e debatidos em aula durante o primeiro semestre de 2024. O objetivo foi compreender o conceito de Tecnologia da Informação e Comunicação (TIC), os tipos de ferramentas digitais de comunicação, suas características a fim de atestar a sua aplicabilidade na educação. O estudo apontou para o desafio dos docentes nas unidades escolares em tempos da era tecnológica, que exige práticas, estratégias voltadas a alcançar a emancipação do aluno e a conquista da autonomia.
Palavras-chave: Educação. Tecnologia. Globalização. Ensino. Docente.
A Study on the impact of digital marketing on export growth
Authors: Moiz Sarwari Abdul , Rasuli Juma 
Published: December 2024

O principal objetivo do marketing é ajudar empresas a aumentar o seu desempenho, colocando seus bens e serviços à disposição dos clientes. Atualmente, empresas competem intensamente entre si para se expandirem e garantirem sua existência a longo prazo no mercado. De acordo com o estudo de Ayyagari, Beck e Demirgüç (2007), a expansão das empresas é crucial para a economia de cada nação como um todo, pelo que devem ser levados em conta também fatores motivacionais adicionais. O recrutamento e a fidelização de clientes são essenciais para muitas empresas afegãs que exportam mercadorias para a Índia. Consequentemente, para atrair clientes em toda a Índia, incluindo nas zonas rurais, as empresas devem ter um objetivo e uma estratégia de marketing claros. Os comerciantes afegãos sempre se basearam no marketing boca-a-boca para divulgar seus produtos e serviços. O paradigma do marketing mudou, deixando de ser o fornecimento de conectividade e passando a ser a venda de mercadorias, à medida que o marketing digital ganhou proeminência. As melhorias tecnológicas, os novos canais de marketing e a mudança em curso no ambiente midiático contribuíram para esta transformação (Bhattacharya e Bolton, 2000). O objetivo deste estudo é determinar o efeito do marketing digital no crescimento das exportações do Afeganistão para a Índia. Criamos o modelo de regressão linear simples para compreender melhor como o marketing digital afeta o crescimento das exportações e as vendas. Os dados, tanto a nível quantitativo como qualitativo, foram recolhidos através de um questionário semi-estruturado e a dimensão da amostra foi de 60 comerciantes.
Palavras-chave: Marketing digital. Estratégia de marketing. Taxa de crescimento das exportações. Aumento das vendas. Experiências da empresa. Fatores.
Políticas públicas no contexto da pesca artesanal em Pernambuco, Brasil
Authors: Ferreira Beatriz Mesquita Pedrosa , Costa Weruska de Melo 
Published: December 2024

O trabalho descreveu a pesca artesanal e suas políticas públicas no Estado de Pernambuco, Brasil, iniciando com o contexto histórico da governança nacional, que culminou com a criação, a partir da demanda dos movimentos sociais, da Secretaria de Pesca Artesanal no recente Ministério da Pesca e Aquicultura. Pernambuco, por outro lado, apesar de ser um estado que se destacou em políticas públicas na pesca, atualmente tem a principal política que promove a participação por meio do Comitê deliberativo ameaçada, visto a inatividade do Comitê. O artigo também mostra como cinco Diagnósticos da Pesca Artesanal realizados ao longo do tempo indicaram as mudanças ocorridas nos últimos trinta anos.
Palavras-chave: Pescadores. Descentralização. Comunidades tradicionais. Governança.
Association of humidity and precipitation with asthma: a systematic review and meta-analysis
Authors: Gu Wangyang , Xie Dan , Li Qinpeng , Feng Huike , Xue Yihao , Chen Yang , Tang Jingyi , Zhou Yushi , Wang Dan , Tong Shilu , Liu Shijian 
Published: December 2024

IntroductionThe relationship of asthma with humidity and precipitation remains controversial. The objective of this study was to investigate the association of increased humidity and precipitation with asthma risk.MethodsA comprehensive systematic search was conducted across various databases, including PubMed, Embase, Cochrane Library, Web of Science, Chinese Wanfang, CQVIP, and CNKI. A total of 21 studies with 1,052,960 participants from 9 countries or regions were included. The fixed and random effect model were used to analyze the data.ResultsThe study revealed a pooled odds ratio (OR) of 1.0489 [95% confidence interval (CI): 1.0061, 1.0935] for the association between humidity and asthma risk. Specifically, among individuals under 18 years of age, the OR (95% CI) was 1.0898 (1.0290, 1.1541). Furthermore, the OR (95% CI) for developing countries or regions was 1.0927 (1.0220, 1.1684), while it was 1.1298 (0.9502, 1.3433) for regions with a high latitude (41°–51°). The pooled OR for precipitation and asthma risk was 0.9991 (0.9987, 0.9995). The OR (95%CI) values were 0.9991 (0.9987, 0.9995), 0.9991 (0.9987, 0.9995) and 0.9990 (0.9986, 0.9994) in people above the age of 18, developing countries or regions, and middle latitudes (31°–41°), respectively.DiscussionThe impact of humidity on asthma risk is particularly pronounced among individuals below 18 years of age, people living in developing countries or regions and in regions located in high latitudes. And the influence of precipitation on asthma persons over the age of 18, developing countries or regions, and middle latitudes significantly. Increased humidity appears to elevate asthma risk, and increased precipitation may reduce the risk. In addition, there appears to be a combined effect of humidity and precipitation on asthma.Systematic Review RegistrationPROSPERO, identifier, CRD42023482446.
A nomogram model to predict non-retrieval of short-term retrievable inferior vena cava filters
Authors: Qin Lihao , Gu Xiaocheng , Ni Caifang , Wang Kai , Xue Tongqing , Jia Zhongzhi , Wang Yun 
Published: December 2024

ObjectiveTo develop and validate a nomogram for predicting non-retrieval of the short-term retrievable inferior vena cava (IVC) filters.MethodsIn this study, univariate and multivariate logistic regression analyses were performed to identify predictive factors of short-term retrievable filter (Aegisy or OptEase) non-retrieval, and a nomogram was then established based on these factors. The nomogram was created based on data from a training cohort and validated based on data from a validation cohort. The predictive value of the nomogram was estimated using area under the curve (AUC) and calibration curve analysis (Hosmer-Lemeshow test).ResultsA total of 1,321 patients who had undergone placement of short-term retrievable filters (Aegisy or OptEase) were included in the analysis. The overall retrieval rate was 68.7%. Age, proximal and distal deep vein thrombosis (DVT) vs. distal DVT, active cancer, history of long-term immobilization, VTE was detected in the intensive care unit, active/recurrent bleeding, IVC thrombosis, and history of venous thromboembolism were independent predictive risk factors for non-retrieval of filters. Interventional therapy for DVT, acute fracture, and interval of ≥14 days between filter placement and patient discharge were independent protective factors for non-retrieval of filters. The nomogram based on these factors demonstrated good ability to predict the non-retrieval of filters (training cohort AUC = 0.870; validation cohort AUC = 0.813.ConclusionThis nomogram demonstrated strong predictive accuracy and discrimination capability. This model may help clinicians identify patients who are not candidates for short-term retrievable filter placement and help clinicians make timely, individualized decisions in filter choice strategies.
Case Report: Surgical treatment of type B aortic dissection in an adult with double aortic arch
Authors: Luo Chong , Bian Longrong , Liang Weitao , Wu Zhong 
Published: December 2024

BackgroundDouble aortic arch (DAA) with type B aortic dissection in adults is a rare aortic vascular disease. The abnormal anatomical structure of the aortic arch in such patients presents significant challenges in the selection of surgical approaches, and there is a notable lack of exploration into endovascular repair approaches that simultaneously preserve asymptomatic vascular rings.Case descriptionA 43-year-old female patient was admitted due to recurrent chest and back pain lasting for over a month. Computed tomography angiography (CTA) indicated a double aortic arch anomaly with localized dissection of the descending aorta. Esophagography with barium swallow revealed vascular indentation on the upper and middle thoracic esophagus, with mild to moderate local narrowing. Based on a comprehensive preoperative evaluation of the imaging and the patient's clinical history, a thoracic endovascular aortic repair (TEVAR) procedure was performed. Considering that the deformity did not cause any clinical symptoms and that the vessel diameter and distance from the proximal anchoring area were sufficient, the posterior section of the dominant arch was chosen as the proximal anchorage zone, and a stent with proximal bare zone was deployed to maintain blood flow to the distal non-dominant arch and preserve the integrity of the vascular ring. Follow-up CTA scans at one- and six-month post-operation showed that the aortic stent was well-positioned, with no visible primary lesion. The patient reported complete resolution of chest pain and no difficulties with swallowing or breathing.ConclusionIn adult patients with DAA complicated by aortic dissection, the abnormal anatomy of the aortic arch poses significant challenges in making treatment decisions. After a comprehensive, multidimensional evaluation of the patient's medical history, CTA, and esophagography, we successfully performed TEVAR procedure. This case provides new insights into the surgical strategy for treating such rare conditions.
Influence of differential source patterns in the detection of signals of disproportionate reporting for PARP inhibitors
Authors: Mestres Jordi 
Published: December 2024

IntroductionCurrent individual case safety report (ICSR) databases contain almost 56 million unique spontaneous declarations of drug-event associations by health professionals but also by patients themselves. These databases have become a useful source for detecting signals of disproportionate reporting (SDR). However, since health professionals use a medical jargon that is often distant from the more colloquial terms used by patients, they usually report more frequently certain adverse events than patients and vice versa. The main objective of this work is to illustrate the existence of different reporting patterns among drugs within a class and to analyze their potential impact on SDR detection.MethodsFour ICSR databases were considered, namely, FAERS, VAERS, JADER, and VigiBase, with reports up until March 2024. They were all integrated in a single database following a careful deduplication and COVID-19 correction protocol. Measures of reporting odds ratio, proportional reporting ratio and empirical Bayesian geometric mean were used to evaluate disproportionate reporting.ResultsThe reporting patterns of four marketed oncology drugs, namely, olaparib, rucaparib, niraparib, and talazoparib, and an investigational drug, veliparib, were compared to those of a diverse set of eight clinically observed SDR, namely, fatigue, asthenia, anaemia, thrombocytopenia, neutropenia, insomnia, intestinal obstruction, and pneumonitis. The source pattern analysis revealed that olaparib and talazoparib are most frequently reported by physicians, and physicians are the main reporters of events such as neutropenia and pneumonitis, predisposing these events to be detected as SDR for those PARP inhibitors. In contrast, rucaparib and niraparib are most frequently reported by American consumers, and American consumers are the main reporters of events such as insomnia and intestinal obstruction, facilitating their detection as SDR for those two drugs. SDR detection was found to be robust to ICSR data completeness.DiscussionMatched reporting patterns between drugs and events may predispose certain drugs to be disproportionally associated with adverse events. Therefore, SDR detected from matched drug-event source patterns in ICSR databases should be challenged during signal validation. Class SDR for drugs with differential source patterns (such as fatigue, asthenia, anaemia, thrombocytopenia, and neutropenia for all PARP inhibitors) usually involve correcting opposite drug-event source patterns.
Undergraduate university students mentoring program: experiences of mentors and mentees
Authors: Al-Aqeel Sinaa , Alhumaid Hana Khalid 
Published: December 2024

IntroductionResearch on the impact of mentoring on students and mentors is limited. Therefore, this study explored the experiences of mentors and mentees involved in a mentoring program for undergraduate students at a governmental academic institution in Saudi Arabia. The program connected undergraduate students with peer students, academic staff, or alumni based on their needs.MethodsUsing an online survey (n = 80) and a focus group (n = 24), we examined mentees and mentors' perceptions of their mentoring experiences. Descriptive statistics were used to summarize participants' responses to the survey. The focus group data were analyzed using six phases of thematic analysis.Results and discussionThe findings showed that the participants' mentoring experience was positive, with some challenges, such as limited time, unmet expectations of mentees, and a lack of student engagement. The motivation to volunteer as a mentor focused mainly on wanting to help others and appreciating the value of mentoring based on the mentors' previous experiences.
Internal structure of giant hail in a catastrophic event in Catalonia (NE Iberian Peninsula)
Authors: Farnell Barqué Carme , Rigo Tomeu , Martin-Vide Javier , Úbeda Xavier 
Published: December 2024

IntroductionOn 30 August 2022, a giant hail-bearing supercell hit Catalonia (NE Iberian Peninsula), producing stones 12 cm in diameter. This is the most severe episode ever recorded in the country. Seventy people were injured, resulting in one fatality; several buildings were severely damaged, which resulted in substantial financial losses (more than €6M).MethodsIn the present study, we analyze the stones collected during fieldwork to gather information on their growth processes. This analysis was conducted considering two lines of investigation. In this paper we focus on the innovative and never-before-used technique of the Computed Tomography Scan, which was utilized to analyze hailstones and their interiors, the outcomes were groundbreaking. It makes it possible to obtain a complete 3D view of the interior of the stone, without producing any alteration in the structure. Through this technology, the different layer densities have been quantified. This is the main novelty of the study and opens a promising door to more analyses in this field.ResultsThe analysis has revealed some interesting results that help to verify previous theories. For instance, the nuclei can be placed far from the stone center, even if the hailstone is externally spherical.DiscussionBesides, a thicker hailstone layer in one direction indicates the falling direction. Finally, the different layer densities show growth process variations.
Ecological risk and chemical speciation of heavy metals in surface sediments of the Pearl River Estuary for comprehensive assessment
Authors: Liu Zhiyan , Wu Qian , He Chao , Zhang Peng , Wang Xiaoqin , Luo Zifen , Yang Liaoyuan , Huang Chaoqing 
Published: December 2024

The Pearl River Estuary, a vital ecological and economic zone in Southern China, has been heavily impacted by industrial discharges, leading to significant heavy metal contamination. To address the ecological implications of different chemical forms of heavy metals, this study systematically evaluated the total concentrations and chemical speciation of Cu, Zn, Cd, and Pb in surface sediments (0–2 cm) collected from 17 sites. Chemical speciation was determined using a modified BCR sequential extraction procedure, and pollution and ecological risks were assessed via the geo-accumulation index (Igeo), potential ecological risk index (RI), and risk assessment code (RAC). The results showed that all four metals exceeded background values, with Cd presenting the highest enrichment (39 times) and contributing 97% of the ecological risk. Speciation analysis revealed that Cd predominantly exists in bioavailable forms, posing severe ecological threats. This study highlights the urgent need for targeted remediation strategies to mitigate Cd contamination and its ecological impact on the estuary.