bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual Emotion Analysis Using Skill-Based Multi-Teacher Knowledge Distillation
Authors: Cladière Tristan , Alata Olivier , Ducottet Christophe , Konik Hubert , Legrand Anne-Claire 
Published: November 2024

Abstract

The biggest challenge in Visual Emotion Analysis (VEA) is bridging the affective gap between the features extracted from an image and the emotion it expresses. It is therefore essential to rely on multiple cues to have decent predictions. Recent approaches use deep learning models to extract rich features in an automated manner, through complex frameworks built with multi-branch convolutional neural networks and fusion or attention modules. This paper explores a different approach, by introducing a three-step training scheme and leveraging Knowledge Distillation (KD), which reconciles effectiveness and simplicity, and thus achieves promising performances despite using a very basic CNN. KD is involved in the first step, where a student model learns to extract the most relevant features on its own, by reproducing those of several teachers specialized in different tasks. The proposed Skill-based Multi-teacher Knowledge Distillation (SMKD) loss also ensures that for each instance, the student focuses more or less on the teachers depending on their capacity to obtain a good prediction, i.e. their relevance. The two remaining steps serve respectively to train the student's classifier and to fine-tune the whole model, both for the VEA task. Experiments on two VEA databases demonstrate the gain in performance offered by our approach, where the students consistently outperform their teachers, and also state-of-the-art methods.
Application of Decision Analytic Modelling to Cardiovascular Disease Prevention in Sub-Saharan Africa: A Systematic Review
Authors: Oguta James Odhiambo , Breeze Penny , Wambiya Elvis , Kibe Peter , Akoth Catherine , Otieno Peter , Dodd Peter J. 
Published: November 2024

Abstract

Background
This systematic review sought to examine the application of decision analytic models (DAMs) to evaluate cardiovascular disease (CVD) prevention interventions in sub-Saharan Africa (SSA), a region which has experienced an increasing CVD burden in the last two decades.
Methods
We searched seven databases and identified model-based economic evaluations of interventions targeting CVD prevention among adult populations in SSA. All articles were screened by two reviewers, data extracted, and narrative synthesis performed. Quality assessment was performed using Philips checklist.
Results
The review included 27 articles from eight SSA countries. Majority of the studies evaluated interventions for primary CVD prevention, with primordial prevention interventions being the least evaluated. Markov models were the most commonly used modelling method. Seven studies incorporated equity dimensions in the modelling, which were assessed mainly through subgroup analysis. The mean quality score of the papers was 68.9% and most studies reported data challenges while only three studies conducted model validation.
Conclusion
The review finds few studies modelling the impact of interventions targeting primordial prevention and those evaluating equitable strategies for improving access to CVD prevention. There is a need for increased transparency in model building, validation and documentation.
Suppressing localized-rail bending modal vibration by designing high-frequency vibration-absorbing fasteners
Authors: Tao Zhecheng , Li Dadi , Wei Lai , Ma Chaozhi , Qu Sheng , Gao Hao , Zhu Bin , Dai Huanyun , Ye Yunguang 
Published: November 2024

Abstract

Since the view that the localized rail 3rd-order bending mode (B3 mode) can cause high-order polygonization (mainly 18~23) of high-speed train wheels was put forward in 2017, many scholars have attempted to link a connection between the localized rail bending modes and wheel polygonization phenomenon and polygonal wheel passing frequency (PWP frequency). Since most of the reported studies did not consider the multi-component assembly characteristics of the fastener system, the phenomenon of localized rail bending modes could not be accurately reproduced by many theoretical models, which hindered scholars from exploring the solution to the polygonal wheel problem. To advance the research on this scientific issue, this paper first establishes a flexible track model considering the structural and parametric characteristics of fasteners, verifies the model by using vehicle tracking test data, and then investigates the influence of fastener parameter matching on the localized rail bending modes, and obtains the following conclusions: (1) There is nearly 1:1 mapping relationship between the localized rail bending modal frequency and PWP frequency, which supports that the localized rail bending mode is one of the causes of wheel polygonization; (2) The iron plate of the fastener system plays a role of dynamic vibration absorber (DVA) in the vehicle-rail coupled system, and the quality of the iron plate and the stiffness of the upper/lower rubber pads significantly influence the localized rail bending modal frequency. Finally, this paper proposes a design principle of a high-frequency vibration-absorbing fastener, which provides a feasible solution to mitigate the localized rail bending modal vibration and high-order wheel polygonization. Meanwhile, it points out that this measure may induce other high-frequency vibration problems, e.g., aggravating modal vibration above 800 Hz. Further, this paper proposes a concept of differentiated arrangement of fasteners, suggesting that different high-frequency vibration-absorbing fasteners be installed in different sections of the whole line to make the localized rail bending modal frequency of the whole line disordered, thus disrupting and further mitigating the development of the wheel polygonization.
Co-loading Radio-photosensitizer Agents on Polymer and Lipid-based Nanocarriers for Radio-photodynamic Therapy Purposes: Review
Authors: Moloudi Kave , Abrahamse Heidi , George Blassan P. 
Published: November 2024

Abstract:
Polymer and lipid-based nanocarriers are a state-of-art in nanomedicine and in co-drug delivery of
drugs that could merges various diagnostic and treatment modalities such radiotherapy (RT), photodynamic
therapy (PDT) and chemotherapy (CT) in cancer therapy. Among various shapes and nanostructures, polymer
and lipid-based nanocarriers have the potential to carry two drugs in same time to cells. However, hydrophobic
and hydrophilic drug can be loaded in between layers as well as in the core of these nanocarriers, simultaneously.
This advantage of NPs can be employed in combination therapy. Radiosensitizer and photosensitizer
agents play a critical role in radio-photodynamic therapy (RT-PDT) of cancer. Co-delivery of these agents to
cancerous cells is advantageous to cancer therapy but still remain as a challenge of RT-PDT. However, in this
review, we have highlighted the challenges of RT-PDT and role of polymer and lipid-based nanocarriers to codelivery
of hydrophobic and hydrophilic agents as radio-photosensitizers. Hence, the different kinds of Poly
(lactic-co-glycolic acid) nanoparticles (NPs) have been categorized. Then, the biophysical mechanism of radio-
photosensitizer agents with co-loading on polymer and lipid-based nanocarriers in RT-PDT treatment of
cancer has been outlined. Finally, attention has been drawn to polymer and lipid-based nanocarriers in codrugs
delivery. Taken together, this work presents the latest updates on this area and highlighted the pros and
cons of co-delivery for RT-PDT purposes.
Sialic Acids and Cancer: Pathophysiological Association between Metastatic Progress and Treatment
Authors: Lu Da-Yong , Lu Ting-Ren 
Published: November 2024

Abstract:
Neoplasm metastasis is a multi-step process with a high rate of cancer mortality
(>60%). Several complex pathogenesis pathways and key therapeutic targets are unclear to us
now. To change this scenario, effective drug targets and underlying mechanisms should be
found, and high-quality metastasis treatment should be supported. Aberrant tumor sialylation
was proposed as a putative drug target candidate to bridge the gaps between metastatic spread
and drug responses (genetic, molecular, and animal models). More recently, several promising
therapeutic mechanisms and benefits against neoplasm metastasis have been observed by potential
association for the target of higher levels and diverse forms of sialic acids (sia) analogues,
antigens, glycan, sialylation enzymes, and conjugates. Subsequently, sia-related pathophysiology
in cancer diagnosis, prognosis, and therapeutic responses has been reviewed. New algorithms,
computation, experimental evaluations, and modern technology might see breakthroughs
in therapeutic targets, responses, and immune regulation via sialylation enzymes, associated
genes, different glycol conjugates, and other hallmarks of cancer.
Redes sociotécnicas como plataformas jornalísticas: análise do jornal O Povo no Instagram
Authors: Almeida Paulo Henrique Soares de 
Published: November 2024

Desde a popularização da internet, as redes sociotécnicas vêm impactando o jornalismo de diferentes maneiras, levando a importância de estudos cada vez mais urgentes sobre como os veículos de comunicação lidam com esses recursos digitais. Para discutir o tema, este artigo faz uma análise de como jornal O Povo utiliza o Instagram para produção de notícia e interação com o público. Por meio da Análise de Conteúdo, o estudo verifica de que forma o veículo se adapta à ferramenta em rede e os recursos utilizados, considerando aspectos como volume, frequência, formato do material produzido e tipos de narrativas. A conclusão mostra que o jornal utiliza o Instagram com coerência, no entanto, ainda é possível explorar melhor os recursos entregues pelo aplicativo, principalmente quanto à produção de conteúdos exclusivos e a interação com o usuário.
Influenciadores e engajadores na gestão da comunicação interna: um modelo para identificá-los nas organizações contemporâneas
Authors: Silva Marcelo Pereira da , Jerônimo Luciana Saraiva de Oliveira , Almeida Fernanda Aquino de Moraes Rêgo 
Published: November 2024

Investigamos o processo de influência em ambientes de trabalho e propomos um modelo de identificação de influenciadores que auxiliem na gestão da comunicação interna das organizações. Desta análise emergem três dimensões de reconhecimento de engajadores: 1. O influenciador sem autoridade; 2. Obediência aos princípios psicológicos; 3. Capacidade de planejar pequenas mudanças. Inferimos que o modelo que apresentamos pode contribuir de modo propositivo com a gestão da comunicação interna já que baseado em significados que constroem vínculos afetivos, simbólicos e relacionais entre as organizações e seus públicos interlocutores.
CONSTRUÇÃO DA IMAGEM DO BRASIL NO ENFRENTAMENTO À COVID-19 PELA REVISTA VEJA
Authors: Moura Adriano 
Published: November 2024

Resumo: Buscamos analisar, sob a luz da semiótica francesa, com base nos trabalhos de Greimas (1977), Greimas e Fontanille (1993) e Fiorin (2002), a construção da imagem do Brasil por parte da revista Veja, no que tange ao combate ao novo coronavírus por parte do governo brasileiro. O nosso corpus foi composto por três capas publicadas pelo semanário, respectivamente, nas edições 2676, de 04 de março de 2020; 2728, de 10 de março de 2021; e 2743, de 23 de junho de 2021. A seleção das capas se deu por meio de um recorte qualitativo, levando em consideração aquelas que abordaram o combate à pandemia por parte do Governo Federal. Além disso, a escolha das publicações respeitou um recorte cronológico: a primeira capa foi publicada logo depois do anúncio do primeiro caso de Covid-19 no Brasil; a publicação da segunda ocorreu aproximadamente um ano após o início da pandemia; e a terceira foi publicada, justamente, depois de o país atingir a vergonhosa marca de 500.000 mortes em decorrência do contágio pelo SARS-CoV-2. Buscamos evidenciar os actantes partícipes dessas narrativas; o contexto de publicação das capas; as principais estratégias discursivas de que lançou mão o sujeito enunciador; e estabelecer a oposição elementar que subjaz a superfície verbo-visual. Após as análises, comprovamos que, no início da pandemia, Veja se mostrava otimista em relação à forma como o país conduziria o combate à pandemia; porém, esse discurso foi-se modificando à medida que o governo foi demonstrando sua inabilidade na contenção do número de contaminados e, consequentemente, de mortes provocadas pela Covid-19.
Palavras-chave: Semiótica. Brasil. Revista Veja. Pandemia. Covid-19.
PROFESSOR DE LÍNGUA PORTUGUESA COMO ELABORADOR DE SEU PRÓPRIO MATERIAL DIDÁTICO PARA O ALUNO SURDO
Authors: Cabral Danúbia , De Fátima da Silva Araújo Frutuoso Aline 
Published: November 2024

A presente pesquisa tem como objetivo analisar o perfil necessário para o professor de Língua Portuguesa (LP) como elaborador do seu próprio material didático para o aluno surdo. Enfatizamos as características e a relevância dele ser produtor do seu material didático, assim como ter as competências e as habilidades necessárias para o Ensino do Português como segunda língua para o aluno surdo. Desse modo, nossa abordagem foi de cunho qualitativo, tendo como tipo de pesquisa a bibliográfica e exploratória. Elaborada a partir de trabalhos acadêmicos nos anos de 2014-2020. Utilizamos os seguintes autores para nortear essa pesquisa: Máximo (2020), Liberali (2008), Geraldi (1996), Koch (2006), Bezerra (2002), Botelho (2005). Como resultados obtidos, constatamos a necessidade do professor ser autônomo, inovador e responsável, mantendo uma postura reflexiva e crítica na sua prática em sala de aula. Assim, o professor ter domínio da Língua de Sinais e da cultura surda contribuirá para que possa ser um exímio produtor de material didático.

Palavras-chaves: Professor de LP. Elaboração de material didático. Aluno surdo. Competências/ habilidades.
Flip the Script: Changing Documentation Standards and Establishing Best Practices for Pharmacists in a Primary Care Setting
Authors: Domanski Nicole , Leung Carmen 
Published: November 2024

Background
Documentation of clinical encounters continues to be a challenge to implement in practice and there is a lack of literature or evidence regarding documentation best practices in pharmacy. In order to inform documentation practices at an academic pharmacy clinic, a quality assurance (QA) initiative was implemented at the UBC Pharmacists Clinic (Clinic).
Goals:
The goal of this QA initiative was to determine what facilitators and barriers existed for the pharmacists in a primary care setting and improve the efficiency of consultation note writing.
Description:
Phase 1 conducted an online survey among Clinic pharmacists to assess each clinician’s documentation practice at baseline. Phase 2 implemented new interventions that could advance these skills. There were four main interventions introduced: 1) revised consultation note templates, 2) a documentation “checklist” to standardize expectations for documentation, 3) a “decision tree” to guide what type of note should be sent following consultations, 4) a documentation “guide” providing tips and examples to improve writing skills and 5) a peer-feedback workshop, where clinicians exchanged consultation notes, provided 1:1 feedback and shared main learning outcomes in a group discussion. During Phase 3, pharmacists re-answered the same survey questions 10 months later. This allowed for a direct comparison of documentation practices and skills before and after the interventions.
Effectiveness:
After the interventions, pharmacists reduced the time to complete their notes by nearly 14 min (from 48 to 34 minutes). In addition, the Clinic has since changed their approach to documentation by starting consultation notes with the clinical assessment and recommendation, followed by subjective and objective information, as opposed to the traditional SOAP format that the previous template followed. The revised note structure resulted in an increased uptake of template use from 37% to 100%. Furthermore, prior to the interventions and workshop, the majority of pharmacists ranked writing consultation notes as the most burdensome aspect of their daily workflow. Afterwards, the level of burden in writing consultation notes reduced significantly. Based on the results of the surveys as well as feedback acquired during this process, the traditional format of the Clinic’s consultation note template was permanently changed, to allow for the most important element, the recommendations, to be documented first. These findings can be used to inform how students are taught documentation and improve the quality of documentation by pharmacists in team-based or primary care settings.
Implementing a Pharmacist-Led Primary Care Pharmacogenomics Medication Management Service
Authors: Taylor Kathryn , Umbreit Audrey , Lea Catherine , Holm Emily , Kosloski Tarpenning Kimberly 
Published: November 2024

Background: Pharmacogenomics (PGx) is a tool to guide optimal medication selection. Increased demand for personalized medicine and the growing occurrence of chronic diseases are drivers for pharmacogenomic medication management services. A review of implementation models identified a paucity of models delivering these services utilizing pharmacists in primary care. Standardization of this process remains a barrier to widespread implementation within health systems.
Purpose: Describe the process and measure the outcomes of developing an institutional guidance document and applying it to implement a pharmacogenomics medication management service at clinic sites within an integrated health system in the United States.
Method: A task force of pharmacists reviewed literature, guidelines, and institutional policies to create a comprehensive guidance document. The document included six minimum practice requirements for implementation in the primary care setting, and six additional recommendations. A retrospective chart review of all PGx visit types occurring from January 1, 2022 through September 30, 2022 was conducted.
Results: A pharmacist-led pharmacogenomics medication management service is now offered at all primary care sites within the health system. During the study timeframe, 1378 patients had a PGx visit, resulting in 1939 PGx visits. Of those visits, 1777 (92%) were referred by a primary care provider and 1675 (86.7%) were conducted by a primary care pharmacist. Twenty-nine primary care pharmacists offered the PGX service and 25 (89%) completed at least one visit. Patients were referred by providers from 56 of the 64 (87.5%) primary care departments.
Conclusions: Developing an institutional process and guidance document for the implementation of a new pharmacist-led pharmacogenomics medication management service at clinic sites within an integrated health system was beneficial in developing and standardizing the workflow. Dissemination of workflow expectations to the primary care providers and pharmacists resulted in adoption of the service.
Teaching Homeopathy in U.S. Pharmacy Schools
Authors: Khader Esra'a , Doucette William 
Published: November 2024

Objectives: Pharmacists often advise patients on the use of over-the counter (OTC) medications. Such a class of medications that is growing in popularity is homeopathic products. Little is known about student pharmacists are being educated about homeopathy. The objectives of this study were to describe homeopathic topics being taught in pharmacy schools and to evaluate faculty views about pharmacists’ roles in counseling patients about homeopathic products.
Method: A mixed method design collected information about teaching homeopathy in US pharmacy schools. Online surveys were distributed to 3,300 pharmacy practice faculty members representing all schools accredited in the US. Frequencies were calculated to describe faculty characteristics and their responses. Moreover, 18 interviews of faculty involved with teaching homeopathy were conducted to learn about homeopathy teaching and expectations about roles of pharmacists in counseling patients.
Results: Survey data were collected from 365 respondents, with 51.2% of the respondents teaching in public universities, 49.6% having PGY1 training and 35.8% being associate professors. Over half (84 of 137) of the responding schools of pharmacy reported teaching homeopathy to pharmacy students. In addition, most interviewed faculty emphasized that pharmacists should be knowledgeable and able to counsel patients effectively on homeopathic products.
Conclusion: Over half of schools of pharmacy are teaching students about homeopathy topics. Further, there was support for pharmacists being able to counsel effectively about homeopathic products.
Accessibility of Diabetes Therapy Management for Patients with Visual Impairment
Authors: Nguyen Cambrey , Lim Lisa , Conard Emily , Nkemdirim Okere Arinze 
Published: November 2024

Introduction: According to the Centers for Disease Control, 11.8% of adults diagnosed with diabetes have severe vision difficulty or blindness, a complication of uncontrolled diabetes. The study evaluated the accessibility features of the most commonly used injectable products for diabetes and blood glucose monitors and obtained recommendations from manufacturers regarding use of these products in patients with visual disabilities. Additionally, accessibility of the medication guides was assessed using a checklist and screen reader.
Methods: Selection of the most commonly prescribed insulin products, GLP-1 receptor agonist drugs, and blood glucose monitors were identified from the ClinCalc DrugStats database and ADA list. The accessibility features of these products were determined from the medication guides and verification of the information with the manufacturers were done in August 2022. All medication guides were then assessed using a checklist and tested with a screen reader for accessibility. Descriptive statistics were used to report the data.
Results: No injectable products or glucose monitoring systems were fully accessible and manufacturers advised to use the product with caution and/or required assistance from a caregiver or family member. In evaluating the 14 medication guides for accessibility using the checklist, the most common issues were lack of structured headings to help with navigation, no descriptions for images, and tables did not have appropriate headers.
Conclusions: Due to the lack of accessible features on diabetes medical devices and glucose monitoring systems, healthcare professionals can seek alternatives to assist this patient population to effectively manage their therapy.