bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percutaneous coronary intervention or coronary artery bypass graft in left main coronary artery disease: a comprehensive meta-analysis of adjusted observational studies and randomized controlled trials
Authors: Bertaina Maurizio , De Filippo Ovidio , Iannaccone Mario , Colombo Antonio , Stone Gregg , Serruys Patrick , Mancone Massimo , Omedè Pierluigi , Conrotto Federico , Pennone Mauro , Kimura Takeshi , Kawamoto Hiroyoshi , Zoccai Giuseppe Biondi , Sheiban Imad , Templin Christian , Benedetto Umberto , Cavalcante Rafael , D’Amico Maurizio , Gaudino Mario , Moretti Claudio , Gaita Fiorenzo , D’Ascenzo Fabrizio 
Published: August 2018

Background
Treatment of patients with ULMCA (unprotected left main coronary artery disease) with percutaneous coronary intervention (PCI) has been compared with coronary artery bypass graft (CABG), without conclusive results.

Methods
All randomized controlled trials (RCTs) and observational studies with multivariate analysis comparing PCI and CABG for ULMCA were included. Major cardiovascular events (MACEs, composite of all-cause death, MI, definite or probable ST, target vessel revascularization and stroke) were the primary end points, whereas its single components were the secondary ones, along with stent thrombosis, graft occlusion and in-hospital death and stroke. Subgroup analyses were performed according to Syntax score.

Results
Six RCTs (4717 patients) and 20 observational studies with multivariate adjustment (14 597 patients) were included. After 5 (3–5.5) years, MACE rate was higher for PCI [odds ratio (OR) 1.10, 95% confidence interval (CI) 1.07–1.14], without difference in death, whereas more relevant risk of MI was because of observational studies. Coronary stenting increased risk of revascularization (OR 1.52; 95% CI 1.34–1.72). At meta-regression, performance of PCI was improved by use of intra-coronary imaging and worsened by first generation stents, whereas two arterial grafts increased benefit of CABG. For patients with Syntax score less than 22, MACE rates did not differ, whereas for higher values, CABG reduced MACE because of lower risk of revascularization. Incidence of graft occlusion was 3.24% (2.25–4.23), whereas 2.13% (1.28–2.98: all CI 95%) of patients experienced stent thrombosis.

Conclusion
Surgical revascularization reduces risk of revascularization for ULMCA patients, especially for those with Syntax score greater than 22, with a higher risk of in-hospital death. Intra-coronary imaging and use of arterial grafts improved performance of revascularization strategies.
Measurement of platelet p-selectin expression by flow cytometry in patients with acute ischemic stroke
Authors: Kalmarova K , Kurca E , Nosal V , Dluha J , Ballova J , Sokol J , Skornova I , Stasko J , Zolkova J , Vadelova L 
Published: August 2018

Abstract
Aims: The aim of this study was to asses the platelet activation in the acute phase of ischemic stroke and transient ischemic attack (TIA) by defining p-selectin (CD62) expression by flow cytometry in vivo – without stimulation with agonists. We also studied whether antiplatelet therapy supresses the levels of baseline p-selectin expression and verified if there is a correlation between platelet CD62 expression and the type of ischemic stroke.
Methods: We determined the expression of platelet surface p-selectin using whole-blood flow cytometry within the first 48-hours after onset of cerebral symptoms in patients with atherothrombotic and lacunar ischemic stroke and in healthy volunteers. We studied the realationship between antiplatelet medication and the type of ischemic stroke to baseline p-selectin expression.
Results: Patients with acute cerebral ischemia have an excess of circulating platelets that express p-selectin, compared to healthy volunteers. The difference between average p-selectin expression in the group of healthy volunteers and the group of patients with stroke was statistically significant (p-value < 0,000001). Patients with stroke without antiplatelet medication showed a higher p-selectin expression than patients with antiplatelet medication (ASA, CLP, or ASA and CLP), hovewer, the difference was not statistically significant. There is no relationship between CD62 expression and the type of stroke.
Conclusions: We can conclude that p-selectin is a highly sensitive blood biomarker of increased platelet activation. Antiplatelet therapy suppresses baseline p-selectin expression only minimally, insignificantly according to our results.
Non-Syndromic 46,XY Disorders of Sex Development
Authors: Gecz J , Breza J , Banovcin P 
Published: August 2018

Abstract
Non-syndromic 46,XY DSD (disorders of sex development) represent a phenotypically diversiform group of disorders. We focus on the association between gene variants and the most frequent types of non-syndromic 46,XY DSD, options of molecular genetic testing which has surely taken its place in diagnostics of DSD in the past couple of years. We emphasize the need of molecular genetic testing in individuals with non-syndromic 46,XY DSD in Slovak Republic.
Primary Repair of Cleft Lip and Nose in the Neonatal Period
Authors: Valentova Strenacikova S , Malina R 
Published: August 2018

Abstract
Facial cleft malformations belong to the most common problems of the congenital facial anomalies. At the Clinic of Plastic, Aestetic and Reconstructive Surgery at the Faculty Hospital in Banská Bystrica we have been performing primary cleft lip repairs during the first week of life of a newborn since 1995. During this life period the fetal healing still persists. Modern anesthetic techniques have considerably reduced respiratory complications after the lip closure. The adequate postoperative sedation together with monitoring of the pacient remarkably reduces the occurrence of wound dehiscence. The advantages of the neonatal cleft lip repair are the scarless healing, no negative effect on the growth of the middle thirt of the face, as well as the pschychosocial effect on the family and the fact that the ortodontic aparat has not been needed.
Commemoration of Kárpáti Gizella, the first woman who took her degree in medical science in Kolozsvár at Ferenc József University
Authors: Mária Péter H. 
Published: August 2018

Abstract
On 31st of December 1895 Gyula Wlassics (1852-1937), minister of religion and education, published his Decree No 72 039, which allowed women to study medical science, pharmacy and humanities at universities. In Kolozsvár Gizella Kárpáti was the first woman who registered at the Faculty of Medicine of Ferenc József University.
Gizella Kárpáti was born in Kolozsvár on 3rd August 1884. After finishing secondary school in June 1902, in the autumn of the same year she registered at the Faculty of Medicine. The marks she got at the university examinations in the following 10 semesters proved that she could cope with her task. In the years spent at the university she met medical student József Szabó (born in 1882) whom she married later. They both started their medical career at Károly Lechner’s Neuro-Psychiatry Institute. From 1909 Gizella Kárpáti was a payed assistant, from 1911 she became assistant lecturer. Her husband became an assistant lecturer from the year 1908, then he was appointed lecturer and then honorary lecturer. Meanwhile he had to go to the front where he was followed by his wife. In 1919, after the professors of the university refused the act of swearing the oath of allegiance, they both made their escape from Kolozsvár together with the greater part of their fellow professors. After a short time they settled in Szeged, where József Szabó was appointed university professor. Here he published his book „Elmekórtan” in 1925. In the 1927-28 academic year he became dean, then vice-dean of the Faculty of Medicine, but in the year 1929 he died unexpectedly. In Szeged, Gizella Kárpáti being engaged in bringing up her two children, did not work as a physician. One of her children, Miklós, continued his parents’ profession, and became a physician. Gizella and her children returned to Kolozsvár for a short time, between 1940-1944, then they moved to Budapest and finally they settled in Szeged again. In 1929 József Szabó and in 1953 Gizella Kárpáti were entombed in one of the graves of honour of the Szeged central cemetery.
In memory of Fodor József
Authors: Zoltán Ábrám 
Published: August 2018

Abstract
Fodor József (1843–1901) is the founder of Hungarian hygiene who established the second hygiene department and hygiene institute in the world; he was a member of the Hungarian Academy of Sciences. He lived in the era of great microbiological discoveries, and his rich and multidisciplinary work has opened up new directions and approaches in science. For a short period of time he was professor at the newly established university from Cluj (Kolozsvár), later he had important contributions to the Hungarian public health act of 1876. His entire professional career represents a very special model by the messages left behind. He was proposed for Nobel Prize in medical (biological) sciences, but he suddenly died on 20 March 1901.
Accumulation of selected heavy metals in soils and common dandelion (Taraxacum officinale) near a road with high traffic intensity
Authors: Kajka Katarzyna , Rutkowska Beata 
Published: August 2018

Abstract
The aim of the study was to determine the levels of selected trace elements in soils and in the common dandelion depending on the distance from a traffic route. The study was conducted in Warsaw near one of the main roads in the suburb of Ursynów. Samples for testing were taken from the 0–25 cm layer at sites located directly alongside the roadway and at a distance of 30, 60 and 300 m from its edge. The amounts of Pb, Ni, Cu, Zn and Cd in the soils were determined by the AAS method, after extraction in HCl at a concentration of 1 mol·dm−3, and in the aboveground parts and roots of dandelion plants after wet mineralization in a mixture of HNO3 and HClO4 by the AAS method. On the basis of the results obtained, it was shown that the concentrations of the tested metals, both in the soils and in the biomass of the test plant, were highest directly at the edge of the roadway and decreased significantly with the distance away from the road. This correlation indicates a significant impact of road transport on heavy metal levels in the environment bordering a traffic route. It was also shown that dandelion plants accumulate higher amounts of heavy metals in the aboveground parts than in the roots, and the heavy metal contents in the dandelion biomass were found to be significantly positively correlated with the amounts of these elements in the soils.
Effect of variable content of organic matter and carbonates on results of determination of granulometric composition by means of Casagrande’s areometric method in modification by Prószyński
Authors: Warzyński Hubert , Sosnowska Agnieszka , Harasimiuk Andrzej 
Published: August 2018

Abstract
The paper discusses the issue of the admixtures’ effect on results of granulometric composition determinations by Casagrande’s areometric method in modification by Prószyński. An experiment was conducted involving preparation of samples with known granulometric composition and determination of their composition by means of the aerometric method. Three types of samples were prepared: base (control), containing organic matter, and containing carbonates. Results of the determinations showed a considerable effect of the admixture of organic matter and calcium carbonate on the accordance of determinations, depending on their percent content. The study results also confirmed known dependencies of disturbances in proportions between the sandy and silty-clayey fraction. A practical conclusion from the research is the determination of the threshold of the organic matter and carbonates percent content at which the determination should be absolutely preceded by processes of mineralisation and decalcification.
Aplikasi Legalitas Surat Izin Mengemudi (SIM) Berbasis Mobile (Studi Kasus : Polisi Resort Rengat)
Authors: Suryani Des , Yulianti Ana , Zulhelmi Muhammad 
Published: August 2018

Berdasarkan undang-undang nomor 22 tahun 2009 tentang lalu lintas dan angkutan jalan, maka setiap orang yang mengemudikan kendaraan bermotor di jalan wajib memiliki Surat Izin Mengemudi sesuai dengan jenis kendaraan bermotor yang dikemudikan. Dalam hal ini juga nantinya akan adanya sanksi pidana kurungan paling lama 1 (satu) bulan atau denda kepada setiap orang yang mengemudikan kendaraan bermotor di jalan yang tidak dapat menunjukkan Surat Izin Mengemudi yang sah. Dalam proses penegakkan hukum di jalan khususnya di Polres Rengat masih terdapat kendala untuk mengetahui legalitas Surat Izin Mengemudi (SIM) pengendara dimana harus mengecek masa berlaku dari SIM pengendara. Legalitas SIM masih dilakukan secara manual karena minimnya alat untuk membuktikan legalitas SIM pengendara. Dalam penelitian ini telah dibangun sebuah aplikasi yang dapat membantu pihak kepolisian untuk mengetahui legalitas SIM pengendara pada saat penegakkan hukum di jalan. Dalam aplikasi ini menggunakan sebuah database yang terdiri dari 7 (tujuh) table yang saling berelasi. Berdasarkan pengujian terhadap sistem tersebut diperoleh hasil 84%, sehingga sistem ini layak untuk diterapkan.
An Investigation of Thai Students’ English Language Problems and Their Learning Strategies at English Study Program of Teacher Training and Education Faculty of Riau Islamic University
Authors: Wahyuni Sri , Ilyas Muhammad 
Published: August 2018

The purpose of this study was to investigate the English language problems and learning strategies. The study employed a survey design which involved administering questionnaires of rating scales, using Rubin, J., & Thompson, I. (1994) and Rebecca Oxford (1990) Strategy Inventory for Language Learning (SILL), to measure English language problems and language learning strategies from 10 Thai students of English Study Program of Teacher Training and Education Faculty at Riau Islamic University. The result of this study revealed that the most serious problem of Thai students in English Language Learning is listening and writing skills while reading skill is the least problem. Another big problem involved being unable to write an essay within limited time and always have a listening problem. Beside, the problem least mentioned is unable to understand classroom lectures in English. All Participant reported a high frequency use of strategy on the SILL. The participants reported using social strategies most frequently and metacognitive strategies least frequently but in medium range. The most frequently used strategies involved asking lecture or classmate for helping. Not trying guess if they do not fully understand what is being said was the least frequently used.
Classroom Management Difficulties of Practice Teaching Program Faced by English College Students.
Authors: Khulaifiyah Khulaifiyah 
Published: August 2018

Classroom managementis avariety oftypesof activitiesthat intentionallydonebythe teacherin order to createoptimalconditionsfortheteaching and learning processinthe classroom, consist of pre-learning activity, opening, learning activity and closing.This research was to find English students difficulties in managing classroom on practice teaching. The target population of this research was the eight semester students English Academic Year 2012/2013 of FKIP UIR. It was a descriptive research. The instrument were questionaires and interviews.The result of quesionnare and interview of the research show that students who already done practice teaching program still had difficulties in;Pre-Learning, such as checking the readiness of students, space, tools and media.Opening the lesson when practice teaching such as giving apperceptions and delivering competencies (objectives to be achieved) and action plans, and got difficult in doing Learning activityin a systematicstructure and stages. The last, got difficult to closing and giving reflection or create a summary by involving students and do a follow-up to give direction or activity or task as part of remedial or enrichment.
Classroom Activities to Promote Students' Literacy Development
Authors: Rizqiani Diyah ayu 
Published: August 2018

Literacy leads students to academic success. The power of literacy does not only lie in the person’s ability to read and write, but also in the person’s capacity to apply these skills effectively for connecting, interpreting, and discerning the intricacies of the world. The purpose of this study was to describe various learning activities in grade one Ellipse Class. The study was descriptive, in which the researcher described the phenomena in the setting without attempting to make inferences or causal statements. The study was conducted at Budi Mulia Dua Pandeansari Elementary School in Yogyakarta. The instruments of this study were observation sheets, documentations, and interview protocols. The participants of this study were ten students and two classroom teachers of Ellipse Class. The results show that there are interactive activities which are able to promote students’ literacy development such as reading activities, diary writing, project-based activities, and story writing.

Literasi mendorong kesuksesan akademis siswa. Kekuatan literasi tidak hanya terletak pada kemampuan sesesorang untuk membaca dan menulis, tetapi juga terletak pada kemampuan seseorang untuk menggunakan ketrampilan-ketrampilan ini secara efektif untuk menghubungkan, menginterpretasikan, dan mengurai kerumitan dunia. Tujuan penelitian ini adalah untuk menggambarkan berbagai kegiatan di kelas yang dilaksanakan di Kelas Satu Ellipse. Penelitian ini merupakan penelitian deskriptif, peneliti mendeskripsikan fenomena di lapangan tanpa berusaha mencampuri fakta yang terjadi di lapangan. Penelitian ini diadakan di SD Budi Mulia Dua Pandeansari Yogyakarta. Dalam penelitian ini, peneliti menggunakan berbagai instrumen diantaranya lembar observasi, dokumentasi, dan pedoman wawancara. Subjek penelitian ini adalah sepuluh siswa kelas satu Kelas Ellipse. Hasil penelitian menunjukkan bahwa ditemukan berbagai kegiatan interaktif di kelas yang dapat menunjang perkembangan literasi siswa diantaranya kegiatan membaca, menulis buku harian, kegiatan berbasis projek, dan kegiatan menulis cerita.
An Analysis of Studies on Teaching and Learning Reading in Indonesia
Authors: Delfi Sofia , Yamat Hamidah 
Published: August 2018

Various studies on teaching and learning reading in Indonesia have been conducted. In order to know the strengths and the weaknesses of the studies, a thorough study is needed to be conducted. This article is based on a critical analysis on teaching and learning reading in Indonesia for a study “a Case Study on Two Indonesian Learners’ Extensive Reading in English Experiences towards Developing Reading Competency”. It aimed to answer: (1) What were the strengths and the weaknesses of the studies on teaching and learning reading in 2003 to 2013? (2) How were the studies similar and/ or different from the current study”? The critical analysis was conducted by studying twenty articles from 2003 until 2013. The studies were analyzed critically in terms of the strengths and the weaknesses. The findings of the analysis are; (1) The strengths of the studies on teaching and learning reading in 2003 to 2013 were in terms of the topic of the studies indicating that learning English in Indonesian context and the studies on extensive reading were developed gradually. The weaknesses were in terms of the focus of extensive reading and the variation of the research design. (2) The studies were similar with the current study in terms of the concept of extensive reading and the research design. This condition might be considered as an opportunity for the following researchers to conduct a research about learners’ experiences on extensive reading. It is suggested that that teachers, lecturers and the policy makers on language learning concern about how extensive reading is implemented.
Vakalarımız eşliğinde çocukluk çağı trombositozunun değerlendirilmesi
Authors: KARAHAN Feryal , KOZANOĞLU İNCE Banu , ULUKÖKSAL Utku , KARACAY Osen , TÜRKEGÜN Merve , ÜNAL Selma 
Published: August 2018

Amaç: Çalışmamızda polikliniğimize başvuran
hastalar arasında trombositoz sıklığını ve nedenlerini araştırmayı planladık. Yöntem: Mayıs 2014-Mayıs 2015 tarihleri
arasında Mersin Üniversitesi Tıp Fakültesi Çocuk Hematoloji BD’na başvuran,
3400 hastanın laboratuar parametreleri incelendi. Bu inceleme sırasında
trombositozu olan 319 (%11.0) hasta saptandı ve bu hastaların yaş, cinsiyet,
laboratuar parametreleri (hemoglobin, beyaz küre, trombositler) ve tanıları
dosyalarından kaydedildi. Bulgular: Çalışmanın konusunu oluşturan 319 trombositozlu hastanın
197’si (%61.8) erkek, 122’si (% 38.2) kız, yaşları ortalama 72.0±69.0 (1-216
ay) aydı. Hastalarımızın ortalama trombosit sayısı 596 430±286 120/μL (450
000-1 523 000) olarak bulundu. Hastaların hepsinde sekonder trombositoz
mevcutken en sık neden %37.9 ile enfeksiyonlardı. Diğer sık nedenler arasında
orak hücre anemisi (%21.2), demir eksikliği anemisi (%15.4), kollojen doku
hastalıkları (%6.6), hemolitik anemiler (%5.0), splenektomi (%4.4) ve diğer
nedenler (%9.7) olarak belirlendi. Tartışma:
Çalışmamızda en sık trombositoz nedeni, literatürle uyumlu olarak
enfeksiyonlara bağlı bulurken, demir eksikliği ve orak hücreli anemi sekonder
trombositozun diğer sık nedenleri arasında yer aldı. Bölgemizde demir eksikliği anemisinin %70-80
gibi çok yüksek oranlarda olması nedeniyle, bu yüksek oranları görmüş
olabileceğimiz ve bölgesel farklılıklara bağlı olarak orak hücreli anemi gibi
hemolitik anemilerin de ayırıcı tanıda akılda tutulması gerektiğini
düşünmekteyiz.
La Revolución Educativa, una re–organización… ¿educativa?
Authors: Velásquez Palacios Martha 
Published: August 2018

Las interacciones e interrelaciones entre agencias, agentes y discursos del campo educativo nacional obedecen tanto a condiciones particulares de su dinámica como a tendencias de carácter internacional, de allí que para analizar las tendencias educativas nacionales resulte necesario hacer referencia a las internacionales e incluso a tendencias no educativas. Las políticas públicas, en el país, y particularmente las de educación no son ajenas a esto, ellas están inmersas en esas pujas y pugnas propias de un campo. Para analizar la educación en el país y la reorganización educativa propuesta desde la perspectiva oficial en la política pública de la Revolución Educativa, entender la construcción de las nociones que circulan resulta fundamental; dentro de ese proceso, el análisis de la recontextualización de noción de “educación” se propone dentro de esta investigación como primera etapa. Si el asunto del que se habla es la educación, empecemos por ver desde dónde se
habla de el.