bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asymmetric Distribution of Glucose Transporter mRNA Provides Growth Advantage
Authors: Stahl Timo , Hümmer Stefan , Ehrenfeuchter Nikolaus , Fucile Geoffrey , Spang Anne 
Published: July 2018

AbstractAsymmetric localization of mRNA is important for cell fate decisions in eukaryotes and provides the means for localized protein synthesis in a variety of cell types. Here we show that hexose transporter mRNAs are retained in the mother cell ofS. cerevisiaeuntil metaphase-anaphase transition (MAT) and then are released into the bud. The retained mRNA was translationally inactive but bound to ribosomes before MAT. Importantly, when cells were shifted from starvation to glucose-rich conditions,HXT2mRNA, but none of the otherHXTmRNAs, was enriched in the bud after MAT. This enrichment was dependent on the Ras/cAMP/PKA pathway, the APC ortholog Kar9 and nuclear segregation into the bud. Competition experiments between strains that only expressed one hexose transporter at a time revealed thatHXT2only cells grow faster than their counterparts when released from starvation. Therefore, asymmetric distribution ofHXT2mRNA provides a growth advantage for young daughters, who are better prepared for nutritional changes in the environment. Our data provide evidence that asymmetric mRNA localization is an important factor in determining cellular fitness.
MemBright: a Family of Fluorescent Membrane Probes for Advanced Cellular Imaging and Neuroscience
Authors: Collot Mayeul , Ashokkumar Pichandi , Anton Halina , Boutant Emmanuel , Faklaris Orestis , Galli Thierry , Mély Yves , Danglot Lydia , Klymchenko Andrey S. 
Published: July 2018

AbstractThe proper staining of the plasma membrane (PM) is critical in bioimaging as it delimits the cell. Herein, we developed MemBright: a family of six cyanine-based fluorescent turn-on PM probes that emit from orange to near-infrared when reaching the PM, and enable homogeneous and selective PM staining with excellent contrast in mono and two-photon microscopy. These probes are compatible with long-term live cell imaging and immunostaining. Moreover, MemBright label neurons in a brighter manner than surrounding cells allowing identification of neurons in acute brain tissue section and neuromuscular-junctions without any use of transfection or transgenic animals. At last, MemBright were used in super-resolution imaging to unravel the dendritic spines’ neck. 3D multicolor dSTORM in combination with immunostaining revealed en-passant synapse displaying endogenous glutamate receptors clustered at the axonal-dendritic contact site. MemBright probes thus constitute a universal toolkit for cell biology and neuroscience biomembrane imaging with a variety of microscopy techniques.
Mapping and Analysis of QTL for Early Maturity Trait in Tetraploid Potato (Solanum tuberosum L.)
Authors: Li Xingcui , Xu Jianfei , Duan Shaoguang , Zhang Jiaojiao , Bian Chunsong , Hu Jun , Li Guangcun , Jin Liping 
Published: July 2018

AbstractMaturity is one of the important traits of potato. In order to get the genetic segment of potato early maturity trait, a tetraploid potato maturity segregation population of Zhongshu 19 × Zhongshu 3 was used for genetic analysis through the combination of high throughput simplified genome sequencing (2b-RAD) and bulked segregation analysis (BSA). A genetic segment related to the early maturity trait at the 3.7~4.2 Mb locus on the short arm of chromosome 5 was obtained and eight markers were developed based on this segment, while five of them were closely linked to the early maturity trait loci. Moreover, 42 SSR markers were developed based on the reference sequence of DM. Finally, a genetic map of chromosome 5 contained 50 markers was constructed using the Tetraploidmap software. The total map length was 172 cM with an average genetic distance of 3.44 cM. Combining with phenotypic data of the segregation population, we mapped the early maturity trait QTL with the contribution of 33.55% on the short arm of chromosome 5, located at 84cM between the flanking markers SSR5-85-1 and SCAR5-8 with the physical interval of 471kb. Gene annotation showed that there exist 34 genes in this region, 12 of them are unknown function. Among the other 22 annotated genes, E3 ubiquitin ligase gene PUB14 may be related to maturity and regulate tuber formation. Our fine mapping of the early maturity QTL made a solid foundation for cloning of the early maturity controlled gene or genes.Key messageEarly maturity site was mapped using a tetraploid potato segregation population derived from cv. Zhongshu 19 and Zhongshu 3. One major QTL with 33.55% contribution to early maturity was fine mapped in physical interval of 471kb on chromosome 5.
Contracting, property rights and liberty
Authors: Oldroyd David , Tyson Thomas , Fleischman Richard 
Published: July 2018

Purpose
The purpose of this paper is to focus on the labour contract system (LCS) established by the Freedmen’s Bureau after the American Civil War to normalise relations between freed-slaves and their former masters and to uphold their rights as free citizens. In particular, it explains the lack of accountability of employers under the LCS and how this contributed to the system’s failure.

Design/methodology/approach
The paper adopts an archive-based approach to develop and illustrate the labour contracting relationship between freed-persons and property owners and the role accounting played in sustaining this relationship in the immediate post-bellum period.

Findings
The paper finds that the LCS was coercive compared to contemporary business practice in the USA; did not conform to the high ideals of contracting as portrayed by the abolition movement; and was adopted by default rather than design. In the event, the reluctance of the federal government to infringe individual autonomy by imposing an over-arching system of regulation to hold employers to account for upholding their contractual obligations prevailed over the desire to defend the freed-people’s property rights.

Research limitations/implications
This research examines the relationship between labour contracting and property rights as well as the role of accounting in sustaining racial prejudice against freed-persons after the American Civil War. As in many archive-based studies, illustrations are selective and not randomised.

Originality/value
The paper examines the various accountings and accountabilities within the LCS in the context of the underlying ideological tensions and priorities in post-conflict US society.
Using information technology to achieve management innovation
Authors: Nieves Julia , Osorio Javier 
Published: July 2018

PurposeThe purpose of this paper is to assess the relationship between information technology (IT) use and management innovation through the mediator role of knowledge-based resources.Design/methodology/approachThe paper presents empirical evidence from a survey of 109 companies that run hotel establishments in the Spanish territory. A model of relationships is proposed and tested through a system of structural equations.FindingsThe use of IT favors the development of organizational knowledge and the ability to integrate this knowledge. Moreover, a positive and direct relationship was found between IT use and management innovation, and indirectly through organizational knowledge and knowledge integration capability.Research limitations/implicationsThe designed questionnaire did not include any questions related to specific IT tools that could contribute to better knowledge management practices in hospitality organizations, but rather generic questions about IT use. The large number of IT tools that can potentially support knowledge management practices in hospitality companies would make the questionnaire unwieldy for its target respondents.Originality/valueThis paper sheds light on a topic that has hardly been studied in the services literature. Specifically, it addresses the way organizations can facilitate management innovation through the use of IT, while considering the mediator role of knowledge-based resources.
Gender and professional trajectories: management life stories
Authors: Selva Clara 
Published: July 2018

Purpose
The purpose of this paper is to define the gender aspects regarded as relevant in a woman’s career, as well as the situations or elements, which are narrated, as an experience of success or failure in their professional development.

Design/methodology/approach
Through an approach similar to life stories and a longitudinal phenomenological perspective analysis, the author identifies the experiences and feelings of nine women who, in 1998, occupied mid-level positions.

Findings
The stories offer a reading of the trajectory at three different levels: the working environment, the experience undergone and the principles of action developed through their careers. These stories show and demonstrate that gender and subjectivity are intertwined, enacted upon and reproduced in the workplace.

Research limitations/implications
Despite having collected information on two occasions, allowing us to reconstruct their paths and isolate the gender issues from this set, this is not a purely longitudinal research as it includes a longitudinal phenomenological perspective.

Originality/value
The stories have helped to weave the experiences and feelings of more than a decade of professional development and have shown how subjectivity is committed to a world of prescriptions and proscriptions that confers differences applicable to both sexes, where being a woman explains some of the ways in which female roles are understood and interpreted in relation to themselves and their environment.
Distributional effect of the farmer pension program in Taiwan
Authors: Luh Yir-Hueih , Wei Min-Fang 
Published: July 2018

PurposeThe Old Farmer Pension Program (OFPP) represents Taiwan’s long-standing efforts aiming at improving farm household income and well-being; however, how effective the pension program is in terms of achieving the policy agenda has remained unclear. The paper aims to discuss this issue.Design/methodology/approachBased on data drawn from the Survey of Family Income and Expenditure during 1999–2013, two identification strategies are used to examine the effect of OFPP. First the authors apply the Blinder-Oaxaca decomposition to address the concern if the program reaches the socially/economically disadvantaged farm households. The second identification strategy involves using the static and dynamic decomposition approaches to identify the major factors contributing to farm household income inequality and the redistribution role of the OFPP.FindingsResults from the Blinder-Oaxaca decomposition indicate that about 60 percent of the income gap can be eliminated if the pension recipients’ socio-economic characteristics are the same as the non-recipient group, suggesting it is the disadvantaged group that receives the old farmer pension. Moreover, the results suggest the significant contributions of household investments in health and human capital as well as diversification toward nonfarm activities, to income inequality among Taiwan’s farm households. Results from the dynamic decomposition suggest that the first-wave adjustment of the OFPP enlarges farm household income inequality, the following two waves of adjustment, however, plays an equalizing role.Originality/valueThis study adds to the literature by providing a methodological refinement promoting the view that it calls for the use of the dynamic (change) decomposition framework to investigate the inequality-enlarging or inequality-equalizing role each income determinant plays.
The role of organisational culture in the internationalisation of new ventures
Authors: Kumar Nishant , Sharma Dharam Deo 
Published: July 2018

PurposeThe purpose of this paper is to explore how organisational culture affects the internationalisation proclivity of international new ventures (INVs).Design/methodology/approachIn this paper, a resource advantage (R-A) framework is adopted to examine how organisational culture can be a resource for INVs to leverage efficiently and/or effectively in order to make up for their challenges in internationalisation and create value for their international customers. In doing so, this study makes use of examples of five INVs from India, which have successfully achieved international business prowess and superior performance immediately after their foundation.FindingsThe findings reveal that an organisational culture including continuous learning, creativity and innovation, collaboration and sharing, and customer-centricity as traits have a positive influence on INV internationalisation proclivity. Most importantly, fostering a culture of collaboration and sharing can help INVs address resource limitations and augment opportunity discovery in the international market. Furthermore, INVs can benefit more from the “learning advantages of newness” by nurturing continuous learning as part of their culture.Research limitations/implicationsA key limitation of this study is that all the firms selected here are from a single country, India, and it may have effects on the way firms leverage these cultural traits.Practical implicationsFounders of INVs should develop organisational arrangements that encourage openness, creativity, and allows employees to contribute freely and fearlessly through new ideas, process innovations, and so on, and firms should recognise such contributions regularly. INVs can adopt policies and develop mechanisms that encourage employees to share knowledge and resources freely with others in the organisation.Social implicationsGrowth of INVs is closely linked to job creation and economic progress. Policy makers in emerging economies can benefit from this study by developing infrastructure and creating social conditions that support the survival and growth of INVs. Adopting the findings of this study could possibly help INVs succeed in international markets and avoid failures, and thus save societal resources.Originality/valueThe paper highlights the critical role of organisational culture in INVs’ internationalisation thrust. The paper develops testable propositions that delineate both the main effects as well as the other effects of organisational culture on INV internationalisation.
How can firms monitor the move toward optimal working capital?
Authors: Eldomiaty Tarek , Anwar Marwa , Ayman Ahmed 
Published: July 2018

Purpose
The purpose of this paper is to explore the potential benefits of an optimal vs observed working capital; the latter being measured by cash conversion cycle (CCC). Optimal CCC is defined and measured as the CCC that maximizes sales in the last four quarters. The initial exploratory results show that optimal CCC has been shorter than the observed. In addition, shorter CCC is accompanied by higher return on investment.

Design/methodology/approach
The authors use various statistical tools to analyze the differences between determinants of observed and optimal CCC. These statistical tools include Johansen cointegration test, linearity, normality tests, cointegration regression and Granger causality. The authors also use the benefits of discriminant analysis in order to reach a Z-score model that can be used for monitoring the move from an observed to optimal working capital.

Findings
The results show that: significant association exists between volatility of sales and CCC; sales volatility and lagged growth of sales carry relatively the highest weights when a firm moves from observed to optimal CCC; shorter CCC is associated significantly with higher profitability; the observed CCC adjusts to an optimal level; as inflation rises causing potential rise in cost of goods sold, firms prefer staying away from optimal levels of working capital; as economic growth slows down, firms stay at the current level of observed working capital; the results are subject to industry and size effects; and the DJIA and NASDAQ listed firms adjust observed CCC to optimal level slowly.

Originality/value
This paper offers three advances in the literature. The first advance is that the paper determines an optimal level of working capital empirically. To the best of the authors’ knowledge up to the date of submission, other related studies did not include an empirical solution to determine optimal working capital. The second advance is that the paper develops an empirical discriminant model that can be used for monitoring firms’ move from an observed to optimal working capital. The third advance is that optimal working capital shows the empirical integration between short-term and long-term investments that results in an improvement to firm’s liquidity and profitability.
Community interventions in construction health and safety and the implications
Authors: Umeokafor Nnedinma 
Published: July 2018

Purpose
The purpose of this study is to examine the involvement of communities – geographical or geopolitical units, which identifies culture, interest and ethnicity – in construction health and safety (H&S) and the implications. This stems from the unexamined hence poorly understood roles of many stakeholders in the construction H&S management and regulatory regime in Nigeria.

Design/methodology/approach
Interviews with contractors and key informants and a survey of contractors were conducted. Descriptive and inferential statistics and thematic analysis were used.

Findings
There is evidences of community interventions: negotiating with contractors on H&S issues; strongly stipulating that H&S measures are adopted and implemented; and enforcing H&S through both violent and non-violent means. These have no legal backing. There is a relationship between the locations of the projects, urban area and rural area, and six community intervention variables. The study also reveals that among the implications of community interventions in H&S are contractors contextualising H&S in these communities and the tension between parties in construction projects. Again, there is a relationship between the location of the projects and six of the implications including the tension between communities and contractors and between contractors and clients.

Practical implications
In adequately addressing construction safety, health and environment issues in Nigeria, geographic location and socio-cultural consideration are pertinent, a point for policymakers, communities and contractors.

Originality/value
The study draws attention to the geographic location and socio-cultural explanations for the differences in the H&S management, performance and attitudes of contractors in Nigeria. This is the first study that examines the involvement of communities in H&S and the implications.
The attributes of organizational change
Authors: Tang Jie , Mo Li , Liu Wen-Bin 
Published: July 2018

PurposeThe purpose of this paper is to explore the role of person-organization (P-O) value congruence on employees’ coping with organizational change and to test the moderating effect of change event attributesvis-à-visvalue congruence and coping strategies.Design/methodology/approachThis paper uses a four-dimensional design to examine relationships between P-O value congruence and employees’ coping strategies. It discusses moderating effects of change attributes based on an elaboration likelihood model. The sample includes 242 employees from 34 organizations in China. Data are analyzed by a structural equation model, dominance analysis and hierarchical regression analysis.FindingsThis paper provides empirical evidence that the four dimensions of P-O value congruence have different impacts on employees’ coping strategies with change; and the effects are moderated by employees’ perceived scope of change.Research limitations/implicationsFuture research should collect data at different time points during change processes to better understand the influence of value congruence on coping processes. To generalize robustly beyond this case-study requires research across a larger number of individuals and organizations.Practical implicationsAccording to this paper, value congruence between employees and organizations could be better ensured by considering it as an important factor in the recruitment and selection processes, which is more effective in the long run. This is particularly pertinent for those organizations which experience frequent changes.Originality/valueFirst, this paper considers the influences of stable organizational factors and attributes of change events on employees’ coping abilities; these are both ignored in previous studies. Second, it develops a four-dimensional coping with change structure and a two-dimensional measure of change attributes in a Chinese context which are reliable and can thus be employed in future studies.
SOX vs C-SOX: which one works better?
Authors: Bhabra Harjeet , Hossain Ashrafee Tanvir 
Published: July 2018

PurposeThe purpose of this paper is to analyze and compare the influence of the Sarbanes–Oxley (SOX) Act of the USA and the Canadian SOX (C-SOX) through the comparison of corporate acquisitions in these two countries.Design/methodology/approachThe final sample includes 1,187 merger and tender offers undertaken by publicly traded (TSX listed) Canadian firms between 1990 and 2016. The authors use standard event study methodology (Patell, 1976) and Berkovitch and Narayanan’s (1993) seminal method to examine announcement period performance and deal motive, respectively.FindingsThe findings support the pro-regulation hypothesis which states that stricter regulations are more useful. Cross-listed acquirers exposed to SOX regime performed much better (both short- and long-term) than non-cross-listed counterparts with only C-SOX exposure. These findings are both statistically and economically significant.Research limitations/implicationsThis study has direct implications as it provides evidence to the legislatures of the provinces, as well as to the federal government, that stricter regulations are effective and Canada should enact additional corporate legislation. Canada may have fared well in the past, but dynamics are changing and may further change in the future, and therefore, timely and stricter corporate legislation are more appropriate.Practical implicationsThis study has direct implications as it provides evidence to the legislatures of the provinces, as well as to the federal government, that stricter regulations are effective and Canada should enact additional corporate legislation. Canada may have fared well in the past, but dynamics are changing and may further change in the future, and therefore, timely and stricter corporate legislation are more appropriate.Originality/valueThis study contributes to the growing literature of SOX-related studies. This is the first study to investigate comprehensively the differences between the two laws enacted by these neighboring countries. As USA and Canada share largely integrated capital markets and are each other’s biggest trading partner, this genre of research has great value. It is a timely study as the Canadian Federal Government is looking into standardizing corporate legislation across provinces and territories.