bluuebunny/crossref_metadata_2025_split huggingface dataset:
PO-052 Study on the Expression of Inflammatory Factor, chemotactic factor in the Repair of Skeletal Muscle Contusion in Mic
Authors: Zhao Linlin , Xiao Weihua , Xu Xin 
Published: October 2018

Objective To investigate the regulation of muscle inflammatory factors and chemotactic factors during the repair of skeletal muscle contusion in mice.
Methods Forty C57 male mice were needed. Eight for control group (C, n=8) and thirty-tow for muscle contusion group (S, n=32). Subsequently, their gastrocnemius muscles were harvested at 0d, 1d, 3d, 7d, 14d after injury. Hematoxylinand eosin (HE) stain were used to assess the changes of muscle morphology. In addition, the gene expression of inflammatory factors and chemotactic factors was analyzed by real-time polymerase chain reaction.
Results 1、Morphology of skeletal muscles showed signs of regeneration at 3d post injury. The maximumamount of regeneration muscle fibers appeared during one week post contusion. Two weeks post-injury morphology of myofibers nearly recovered to normal. 2、After skeletal muscle injury, macrophage markers (CD68, CD163, CD206), a variety of inflammatory factors (IL-1, IL-6, IL-10) were up-regulated. 3、chemotactic factors (CCL2, CCL3, CCL5, CCL8, CXCL9, CXCL10, CXCL12, mRNA) were up-regulated。
Conclusions After skeletal muscle contusion, the expression of a variety of chemotactic factors is up-regulated, which promotes macrophage infiltration and produces a variety of inflammatory factors. They may be involved in the inflammatory response and regeneration process after skeletal muscle contusion.
PO-055 Changes of trace elements in skeletal muscle and serum of rats after exercise-induced injury
Authors: Liu Jingyun , Zuo Qun 
Published: October 2018

Objective This study is to investigate the changes of trace elements (Cu, Fe, Zn, Se, Mg) in serum and skeletal muscle of rats after skeletal muscle injury induced by downhill running, and to find out the change regularity of trace elements in the body after exercise injury. To provide experimental basis for how to use trace elements supplements reasonably.
Methods Fifty-four healthy male Sprague-Dawley rats aged 8 weeks were randomly divided into two groups: control group (C, N=6) and exercise group (E, N=48, include: 0 h group, 6 h group, 12 h group, 24 h group, 48 h group, 72 h group, 1- week group and 2- week group). The rats in exercise groups run down a 16°incline at 16m/min for 90 minutes. At the end of the exercise, the rats were killed at 0 h, 6 h, 12 h, 24 h, 48 h, 72 h, 1 week and 2 weeks, respectively. The serum was got from the inferior vena cava blood and diluted by 1% nitric acid. The muscle was got from the right side of the rat's sural which were digested by concentrated nitric acid and 30% hydrogen peroxide in 75℃water bath for 20mins. The content of trace elements in muscle and serum were measured by inductively coupled plasma atomic emission spectrometry (ICP-MS). All the data are analyzed and processed by SPSS22.0 statistical software.
Results (1) The contents of trace elements in serum showed: Cu, Zn, Mg, Se decreased immediately after exercise, but the Cu still increased to reach a peak at 24h after decreasing, and after 2 weeks the content of Cu was slightly lower than pre-exercise level. However, the content of Zn did not elevate again, it continued declined to the lowest at 24h which was significantly lower than control group (P < 0.05). And after 2 weeks, Zn did not return to the pre-exercise level. The changes of Mg, Se in serum was not statistically significant. There is no difference between 0h and control groups in content of Fe, after that Fe decreased continually and appeared the least value at 24h, the differences between immediate group and control group were statistically significant (P < 0.05). Fe returned to the pre-exercise level after 2 weeks. (2) The contents of trace elements in muscle showed: Most of trace elements increased to the maximum level at 6 h, after that Mg, Fe, Cu decreased to the lowest value at 72 h which were significant lower than 0h group or 6h group (P < 0. 05). ALL the trace elements were lower than pre-exercise level. There was no statistical difference in the content of Se in muscle.
Conclusions (1) The different changes of trace elements in skeletal muscle and serum after exercise injury may be due to the redistribution of trace elements caused by the body adaptability. (2) The most obviously changes of trace element in serum and muscle are Cu and Zn. Both of them did not return to the pre-exercise level after 2 weeks, it suggests that the supplement include Cu and Zn may play an important role in recovering after exercise-induced injury.
PO-060 Changes of Cardiovascular Function during Exercise Tolerance Testing in Sedentary Postmenopausal Women after Exercise Intervention
Authors: Zhang Peizhen 
Published: October 2018

Objective Previous studies suggested that being postmenopausal could increase the risk of cardiovascular disease(CVD). If we can master the change characteristics of postmenopausal women’ cardiovascular function when they doing exercise, we may prevent or reduce the risk of CVD which induced by exercise. To get a more accurate tolerant judgment of the intensity of exercise, we discussed the change of cardiovascular function in sedentary postmenopausal women during exercise tolerance testing after exercise intervention, wish to provide more reliable theory basis in preventing exercise emergence and make an appropriate exercise prescription.
Methods Thirty postmenopausal women participated the study. PAR-Q questionnaires and International Physical Activity Questionnaire-Short Forms were used to screen participants. They were randomly divided into control group(n=15) and experimental group (n=15). The experimental group had an exercise intervention with 3 months walking while the control group lived as usual. Using an exercise tolerance testing by cycle ergometer, let participants do one-time maximal graded exercise test to exhaustion, get the indicators of heart rate, blood pressure, VO2max, then analyzed the changes of cardiovascular function indexes before and after exercise intervention in experimental group, compared with control group in the same age categories, explored the similarities and differences between index variation.
Results (1) After 3 months of exercise intervention, the rest systolic blood pressure in the experimental group was significantly lower than that in the control group(P<0.05). (2) With the increase of exercise intensity, heart rate tend to rise in both two groups (P<0.05). After 3 months of exercise intervention, the amplitude of heart rate variation between two intensities got smaller in the experimental group. (3) With the enlargement of exercise intensity, systolic blood pressure tend to increase in both two groups (P<0.05). After 3 months of exercise intervention, the amplitude of systolic blood pressure variation between two grades got smaller in the experimental group. (4) The exercise intervention can effectively improve the cardiac functional capacity of postmenopausal women (P<0.05).
Conclusions Exercise for 3 month can efficiently increase the ability of postmenopausal women’s cardiovascular system in the quiet state, increase the reaction and adaptability of intensity stimulation of heart.
PO-065 The Role and Mechanism of Endocannabinoid System in Exercise-induced Antinociception
Authors: Xu Guoqin , Zhao Hong 
Published: October 2018

Objective As we all know, exercise can enhance the will, improve the mood, and counteract the bad feelings of the body, but the cause and mechanism of action have not been clear. The endocannabinoid system is an important regulatory system in the central nervous system that regulates cognition, mood and behavior. Endocannabinoids can exert physiological regulation through cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2). Cannabinoid receptors are widely distributed in the body and participate in the regulation of anti-nociceptive signals at multiple levels. This study will explore the role and mechanism of the endocannabinoid system in exercise-induced antinociception by literature research methods.
Methods Using endocannabinoid, exercise/sports and antinociception or emotion as keywords, using Pubmed, Medline, and Embase databases to search for nearly 15 years of research literature and the literatures from cross-references of journals, after excluding the literature that is not relevant to the research content, the 12 articles included were analyzed.
Results Exercise can activate the endocannabinoid system, the degree of activation is related to exercise intensity, and high-intensity exercise significantly increases endocannabinoid levels in the human body. Cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2) are widely distributed in the nervous system including the central nervous system and the peripheral nervous system. When exercise activates the endocannabinoid system, the increased endocannabinoid in the circulatory system activates CB1 and CB2 receptors, promotes hyperpolarization of the nervous system cells, reduces the rate of excitable cell release, and inhibits neurotransmitters, and reduce nociceptive impulses, thereby the body produces anti-nociception. Pretreatment with endocannabinoid metabolic enzyme inhibitors (MAFP, JZL184) and endocannabinoid reuptake inhibitors (VDM11) can be extended and enhanced the antinociceptive effect of exercise. Pretreatment with endocannabinoid receptor antagonists (AM251 and AM630) will inhibit the antinociception induced by aerobic exercise in mechanical and thermal nociceptive tests.
Conclusions Exercise can enhance the level of circulating endocannabinoids, activate the endocannabinoid system through endocannabinoid receptors, and then induce the body to produce anti-nociceptive effects. The degree of activation is related to exercise intensity. Studying the role and mechanism of the endocannabinoid system in exercise-induced antinociception can provide a theoretical basis for exercise to improve depression, anxiety and other emotions, improve the sense of life and prevent mental disorders.
PO-078 Effects of aerobic and resistance training on cardiac diastolic dysfunction in type 2 diabetic rats
Authors: Li Shunchang , Gao Derun , Laher Ismail , Su Quansheng 
Published: October 2018

Objective To compare the effects of two types of physical training on cardiac diastolic dysfunction in type 2 diabetes mellitus and investigate the role of passive tension regulators—titin and collagen.
Methods Sprague-Dawley (SD) male rats were divided into two groups: control and diabetes. Each group was subdivided into three subgroups: sedentary rats, rats submitted to aerobic trained and rats submitted to resistance training. Diabetic rats were induced by high-fat diet combined with low-dose injections of streptozocin (STZ). Aerobic trained rats ran on a treadmill at 21m/min for 60 min per day, while resistance trained rats climbed a ladder with incremental loads. The train period lasted for 8 weeks.
Results All diabetic rats had increased fasting blood glucose (FBG) and left ventricular end diastolic pressure (LVEDP), a lower down stroke of the pressure curve (dp/dt min), longer exponential time constants of relaxation (Tau) in relation to control rats, while the protein expression of titin was decreased significantly, and the expression of collagen I, TGFβ1 were increased slightly, the ratio of type I and III collagen was raised in diabetic rats. Both types of training promoted a decrease in FBG and HOMA-IR in diabetic rats. Aerobic exercise trained diabetic rats had significant higher –dp/dtmin, and shorter Tau, but -dp/dtmin and Tau in resistance exercise trained diabetic rats had no significant been improved, even more aggravation. Moreover, aerobic training increased the protein expression of titin and HSP27, and the amount of co-localization of titin and HSP27 elevated, the protein expression of collagen I, TGFβ1 were decreased, and the ratio of type I and type III got close to normal. Resistance training further decreased the expression of titin, collagen I, and TGFβ1, collagen volume fraction (CVF) was increased significantly, and the ratio of type I and III collagen was disturbed, but the co-localization of titin and HSP27 elevated slightly.
Conclusions Aerobic training ameliorates cardiac diastolic dysfunction in diabetes and this improvement may be related to increase titin repaired by HSP27, while resistance training aggravates the cardiac diastolic dysfunction in early diabetes mellitus and it could be caused by worsening myocardial interstitial fibrosis.
PO-082 16-Week high intensity interval training does not alter LKB1 and AMPKα protein in Rats Liver
Authors: Shao Jia , Su Hao , Jiang ZhongYe , Kong ZhenXing , Cao GuoHuan , Wen TianHao , Liu YiYi 
Published: October 2018

Objective Liver, as one of the most important organs involved in lipids and glucose metabolism, yet no study has examined the response of liver kinase B1 (LKB1) and AMP-activated protein kinase α(AMPKα) signaling after high intensity interval training. This study aims to evaluate the effect of 16-week high intensity interval training intervention on the expression of LKB1、AMPKα in liver of aging rats.
Methods 8 -month-old male Wistar rats（n=40）were randomly divided into control group (C) and HIIT group (H). Group H with 70%-90%-50%VO2max intensity training for 50min/ day, 5 days / week, lasted for 16 weeks. Rats were killed on 0, 8 and 16 weeks. We examined the protein expression of LKB1 and AMPKα in liver. Proteins were analyzed by western blot analysis. Data are mean±SD; for ANOVA, p<0.05 was significant.
Results The AMPKα levels in group C and group H increased with time and there was no significant difference between the groups. The content of LKB1 in group C and group H both increased first and then decreased, but there was no significant difference between the groups.
Conclusions 16-week high intensity interval training intervention had no effect on LKB1, AMPKα protein expression in aging rats.
PO-085 Investigation and assessment of nutritional status among Chinese elite artistic swimming athletes
Authors: Li Liang , Xu Jianfang , Fang Huayu , Wang Xiaojing 
Published: October 2018

Objective The sport of artistic swimming is unique which requires a mixture of endurance, power, acrobatics, ﬂexibility, and eurhythmics to produce an artistic performance. Optimal nutrition plays an important role in attaining high level of achievements for artistic swimming athletes, a poor nutritional status will significantly affect their health, athletic performance and post-exercise recovery. However, the assessment of nutritional status among artistic swimming athletes is very lack. The purpose of present study was to assess the nutritional status of Chinese elite artistic swimming athletes and provide suggestions for them to modify their dietary structures.
Methods During the summer training season before the 17th FINA World Championships, 17 Chinese elite artistic swimming female athletes participated in this study. After an overnight fast, the anthropometric data including height, weight, BMI, body fat percentage (BF%), and waist/hip ratio were collected in the early morning around 7 a.m. before breakfast. The 24 hours dietary recall was used to collect dietary intake data of individuals, the athletes were required to record their daily dietary intake in the structured questionnaire for 2 work days and 1 weekend day. During data processing, the cooked foods were converted into raw amounts of each food material by standardized recipe method, and the nutritive value was calculated by using a dietary nutrients analysis software.
Results The athletes were 19.6±1.7 years old and their training age was 10-12 years. The athletes’ BMI was 18.3±1.4 kg/m2, their BF% and waist/hip ratio was 16.6±2.6% and 0.85±0.02 respectively. Even the athletes’ body composition level was in the normal range, the BMI and BF% were lower than Russia and Spain artistic swimming athletes. The daily energy intake was 1528±276 kcal which was composed of 435±50 kcal breakfast, 477±62 kcal lunch, 402±49 kcal supper, and 214±22 kcal snacks. However, the energy intake was much lower than the recommendation of 3500 kcal/day. Carbohydrates provided approximately 51% of total energy which was lower than the practical demands, but both fats and proteins provided more energy (31.3% and 17% respectively) than the recommendations. In addition, the supplementation of many important vitamins and minerals, except vitamin E and sodium, were not reached the recommended level, for example, the consumption of vitamin C and calcium was only 46±12 mg and 430±72 mg per day.
Conclusions The data showed that the nutritional status was unsatisfactory among Chinese elite artistic swimming female athletes, the dietary energy intake and many important vitamins and minerals were much lower than the recommendations. In order to keep healthy and increase the exercise performance, it was suggested that the artistic swimming athletes should modify their dietary structures to supply more energies, vitamins and minerals according to their physical conditions and training arrangements.
PO-086 Exercise enhances cardiac antioxidant capacity in diabetic rats through the Keap1/Nrf2 signaling pathway
Authors: Wang Shiqiang 
Published: October 2018

Objective To investigate the effects of exercise on the myocardial oxidative stress injury of diabetic rats, and discussed the role of Keap1/Nrf2 signaling pathway in this process
Methods Tyep 2 diabetic rat model was established by streptozotocin injection through abdominal cavity and high fat diet. The all the diabetic rats were divided into three groups: control group (NC), diabetes group(T2DM) and diabetes exercise group, NC and T2DM group were kept quiet for 8 weeks, T2DME group was trained for 8 weeks. After the exercise, weight, heart weight and blood were measured. MDA, T-SOD and GSH-PX enzyme were measured by biochemical method. Ho-1, Keap1, Nrf2 gene and protein expression were detected by RT-PCR and WesternBlotting.
Results Compared with NC group, the weight of rats in the T2DM group significantly decreased [(528+/-71g vs 362+/-33g), P<0.05], HWI significantly increased [(2.845+/-0.22 vs 3.841+/-0.21, P <0.05], blood glucose was significantly increased [(6.4±3.8 vs 26±7.5mmol/L), P <0.01],T-SOD and GSH-PX activity decreased significantly (P<0.05), Ho-1 protein expression increased (P<0.01), Keap1 and Nrf2 showed no significant changes, and Nrf2 nuclear transposition decreased (P<0.05). Compared with the T2DM group, no significant change in body weight and heart weight in the T2DME group, with significant decrease in HWI[（3.841±0.21 vs 3.235±0.23），P＜0.05], with significant decrease in blood glucose [（26.0±7.5 vs 21.0±6.8），P＜0.05]. Ho-1 gene and protein expression increased significantly（P＜0.05and P＜0.01）, with no significant change of Keap1, while Nrf2 expression increased significantly (P < 0.05), and Nrf2 nuclear transposition increased significantly (P < 0.01).
Conclusions Exercise activates the myocardial Keap1/Nrf2 signaling pathway in rats, promotes the expression of downstream antioxidant enzymes, increases cardiac antioxidant capacity, and resists diabetic myocardial oxidative stress injury.
PO-004 The influence of lifestyle on the quality of life of breast cancer patients
Authors: Dong Heling , Tian Zhenxiang 
Published: October 2018

Objective To explore the effects of healthy lifestyle such as exercise and diet on health-related quality of life in patients with breast cancer.
Methods 427 breast cancer patients who met the inclusion criteria were investigated and analyzed. All the patients were collected in the department of oncology of a third-class first-class hospital from January 1, 2015 to June 30, 2016.
The cancer treatment quality of life core scale (EORTC QLQ-C30) and cancer treatment function evaluation system scale (FACT-B) were used to investigate and collect the questionnaire for statistical analysis of all data.
Results The scores of health-related quality of life were higher in regular exercise than those in non-regular exercise. Patients who ate more than 300g of vegetables per day had higher health-related quality of life scores. The scores of health-related quality of life were higher in patients who ate more than 200g fruit per day (p<0.05). Patients with two healthy lifestyles had higher health-related quality of life scores than patients with one healthy lifestyle (p<0.05).
Conclusions Multi-frequency exercise and adequate intake of vegetables and fruits play a positive role in the health-related quality of life of breast cancer patients. Breast cancer patients with two healthy lifestyles had significantly better health-related quality of life than patients with one healthy lifestyle. Healthy lifestyle with adequate exercise and adequate intake of fruits and vegetables should be paid more attention to in improving the health-related quality of life of breast cancer patients.
PO-005 The Dietary Nutrition Adjustment Continuous 16 Weeks and the Nutrition Supplement Plan after Weighing of Women's Wrestlers
Authors: Liao Jingjing 
Published: October 2018

Objective This study develops the nutrition supplement plan after weighing, and research how to supply nutrition in this important time on the basis of the dietary nutrition adjustment in pre-competition. Formulate the nutrition supplement plan for women’s wrestlers by quantized, and evaluate this plan.
Methods To prepare for the key players of the 13th National Games, a 16-week daily dietary adjustment was conducted according to the results of a nutrition survey on the slow-fall-weight control phase before the competition. Routine dietary adjustment was proved by changes in body composition and improvement of anaerobic capacity. The plan was developed, that includes weighing meals, liquid nutritional supplements and inorganic salts solutions after weighing, on the basis of the regulation on nutrition.
Results The balance between the total daily dietary intake and its ratio can make the athlete achieve the ideal effect of weight control in the normal training. Comparing the indicators before and after 16 weeks, it was found that after the athlete's diet was basically balanced and reasonable the body weight decreased significantly, the fat-free body weight remained unchanged, the body fat percentage decreased significantly, and the anaerobic capacity increased significantly. After weighing during the competition nutritional supplement plan can be executed, and the total body water, urine protein, urine specific gravity can be restored to normal levels developed, that includes weighing meals, liquid nutritional supplements and inorganic salts solutions after weighing, on the basis of the regulation on nutrition.
Conclusions This study through the understanding of the basic nutritional status of athletes before the game, according to the conditions of each athlete to give the corresponding dietary guidance, and use 16 weeks to supervise the implementation. Athletes' dietary structure and nutrient intake change significantly, and then the nutrition achieves balanced and reasonable. To investigate the nutritional situation this time, that combined with the characteristics of energy supply and nutritional, which for wrestling athletes, worked out the nutritional supplement plan after weighing by quantitative data. This plan can be performed well; the effect of supplement is improved obviously; and on discomfort appeared during the game by the athletes who performed it. This study is a preliminary exploration of the nutritional supplement plan for athletes during the important recovery phase of the game. Follow-up research will involve more projects in order to promote this special period to other weight-level projects eventually.