bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of weather and climate on seed protein and oil content of soybean in the North Сaucasus
Authors: Novikova L. Yu. , Seferova I. V. , Nekrasov A. Yu. , Perchuk I. N. , Shelenga T. V. , Samsonova M. G. , Vishnyakova M. A. 
Published: September 2018

For a targeted search of initial breeding material for the quality of soybean seeds, it is necessary to know the patterns of the dependence of the corresponding seed characters on the weather and climatic conditions in a particular region. Global climatic change, the concretization of which is relevant, has a share in this dependence. Thus, the aim of this work was to identify the relationship between the variability of protein and oil content in soybean seeds with climatic parameters in the North Caucasus as well as trends in this variability over a long time period. The study of 1 442 soybean accessions from VIR collection in the Krasnodar region during 1987–2015 had been carried out and the tendencies of the variability of protein and oil content in seeds in this environment were estimated. The regression analysis in differences with forward stepwise selection of variables has been used to construct models for the dependence of the protein and oil content on generalized agrometeorological indices. During 1987–2015, for the period with temperatures above 10 °C, the sums of active temperatures increased by 218 °C/10 years and precipitation decreased by 20.9 mm/10 years. In the dynamics of protein content, a trend has been revealed as an increase by 2.5 % over 10 years, while there is no reliable trend in oil content. The maximum average mean of oil content and the smallest protein were in the middle-maturing accessions (22.2 and 38.8 %), and a relatively high protein content was detected, on average, in the early- (21.6 and 40.0 %) and late-maturing (20.2 and 39.9 %) varieties. The protein content had been increasing with a growth of the duration of the period with temperatures above 22 °C and decreasing with a raise in precipitation over a period of temperatures above 18 °C. The accumulation of oil in seeds was promoted by an increase of the hydrothermal coefficient over the period with temperatures above 19 °C, and, in late-maturating varieties, prevented by a prolonged autumn period with temperatures below 15 °C. Long-term growth in protein content is due to both climatic change and genetic improvement of varieties.
Analysis of mutations in CDC27, CTBP2, HYDIN and KMT5A genes in carotid paragangliomas
Authors: Lukyanova E. N. , Snezhkina A. V. , Kalinin D. V. , Pokrovsky A. V. , Golovyuk A. L. , Stepanov O. A. , Pudova E. A. , Razmakhaev G. S. , Orlova M. V. , Polyakov A. P. , Kiseleva M. V. , Kaprin A. D. , Kudryavtseva A. V. 
Published: September 2018

Carotid paragangliomas (CPGLs) are rare neuroendocrine tumors that arise from paraganglionic tissue of the carotid body localizing at the bifurcation of carotid artery. These tumors are slowly growing, but occasionally they become aggressive and metastatic. Surgical treatment remains high-risk and extremely challenging; radiation and chemotherapy are poorly effective. The study of molecular pathogenesis of CPGLs will allow developing novel therapeutic approaches and revealing biomarkers. Previously, we performed the exome sequencing of 52 CPGLs and estimated mutational load (ML). Paired histologically normal tissues or blood were unavailable, so potentially germline mutations were excluded from the analysis with strong filtering conditions using 1000 Genomes Project and ExAC databases. In this work, ten genes (ZNF717, CDC27, FRG2C, FAM104B, CTBP2, HLA-DRB1, HYDIN, KMT5A, MUC3A, and PRSS3) characterized by the highest level of mutational load were analyzed. Using several prediction algorithms (SIFT, PolyPhen-2, MutationTaster, and LRT), potentially pathogenic mutations were identified in four genes (CDC27, CTBP2, HYDIN, and KMT5A). Many of these mutations occurred in the majority of cases, and their mutation type was checked using exome sequencing data of blood prepared with the same exome enrichment kit that was used for preparation of exome libraries from CPGLs. The majority of the mutations were germline that can apparently be associated with annotation errors in 1000 Genomes Pro ject and ExAC. However, part of the mutations identified in CDC27, CTBP2, HYDIN, and KMT5A remain potentially pathogenic, and there is a large body of data on the involvement of these genes in the formation and progression of other tumors. This allows considering CDC27, CTBP2, HYDIN, and KMT5A genes as potentially associated with CPGL pathogenesis and requires taking them into account in further investigations. Thus, there is a necessity to improve the methods for identification of cancer-asso ciated genes as well as pathogenic mutations.
Inovação sustentável: quais ações tornam as empresas inovadoras e sustentáveis em destaques no mercado global
Authors: Unglaub Delton Lehr , Simprini Eduardo 
Published: September 2018

O objetivo deste estudo é verificar os fatores que permitiram empresas a se destacarem em ambos os ramos da inovação e da sustentabilidade. A pesquisa consistiu em analisar as práticas de empresas que obtiveram destaque global nos quesitos de sustentabilidade e inovação corporativa. Foram realizadas quatro etapas: 1) coleta de dados sobre a classificação (ranking) de empresas mais sustentáveis e de empresas mais inovadoras no mundo, 2) comparação entre ambas as classificações, 3) análise quantitativa das classificações e 4) análises qualitativas das informações obtidas nos sites das empresas inovadoras e sustentáveis. As principais contribuições deste estudo foram: a) a verificação da utilização de inovação para alcançar resultados expressivos no desenvolvimento sustentável e b) a confirmação da importância de inovar em processos e produtos sustentáveis para que as organizações ofertem novidades ao mercado, além de causarem um impacto em seu processo produtivo e no ambiente em que estão inseridas.
Lucro real x lucro presumido: um estudo de caso no setor da construção civil
Authors: Quagliato João Daniel , Gonçalves Liliane Lopes 
Published: September 2018

Devido à elevada carga tributária existente no Brasil, as empresas buscam soluções para reduzir o peso dos tributos sobre o custo de seus produtos e serviços, de maneira que possam manter-se atuantes de forma competitiva nomercado altamente concorrido. Uma dessas soluções é a análise tributária, quevisa identificar quais tributos deverão ser pagos e como podem ser minimizados,possibilitando reduzir os custos de produção, administração e comercializaçãoe, consequentemente, elevar os lucros da empresa. O trabalho utilizou-se do método exploratório-descritivo e natureza quanti-qualitativa, com base em pesquisa bibliográfica e documental. O presente estudo teve por objetivo analisar se a alteração do regime de tributação do Lucro Real Trimestral para o Lucro Presumido foi uma decisão acertada financeiramente para uma empresa do setor da construção civil, localizada em Monte Sião (MG). Para tal, foram analisados os anos de 2013 e 2014, em que a opção de regime tributário era o Lucro Real Trimestral, enquanto que no ano de 2015 os gestores decidiram alterar o regime, passando para o Lucro Presumido. Foram abordados os conceitos relativos à tributação conforme a legislação tributária nacional vigente. Os dados foram obtidos, sobretudo, das demonstrações contábeis e de documentos como balanço patrimonial e planilhas, disponibilizados pela contabilidade da empresa pesquisada. Este estudo possibilitou obter resultados que identificaram que o regime tributário que, comprovadamente, reduz custos relativos aos tributos é o Lucro Presumido, nos respectivos anos considerados, 2013 e 2014. Devido à política da empresa, os dados referentes ao ano-calendário de 2015 não foram concedidos, porém, se a empresa se mantiver nos mesmos padrões de receita, custos e despesas, provavelmente reduzirá a carga tributária, portanto, notou-se que foi uma decisão assertiva alcançando uma redução do ônus tributário.
Um estudo sobre a prevenção de fraude contábil em uma empresa de comércio exterior
Authors: Pereira Viviane Fernandes , Santos Adilson Das Neves , Da Rocha Luis Fernando 
Published: September 2018

A Contabilidade tem o propósito de fornecer informações úteis e tempestivas para a tomada de decisões de forma plena e adequada. Porém, a sociedade tem observado escândalos relacionados à fraude, como adulteração, manipulação e omissão de dados/fatos. O objetivo deste estudo é verificar se os procedimentos utilizados para a prevenção de fraude contábil em uma empresa de comércio exterior são suficientes para impossibilitar a sua ocorrência. Utilizou-se pesquisa bibliográfica, exploratória e qualitativa, o questionário em escala Likert foi aplicado em cinco profissionais da área contábil, cinco do fiscal e três do controle interno. Verificou-se que existem significativas falhas no que discerne aos controles primordiais para prevenção de fraudes, e que os níveis hierárquicos, em várias ocasiões, não indicam trabalhar/operar adequadamente, em razão das opiniões divergentes em relação à questões primordiais para a empresa. A fraude em si não foi detectada, mas existem muitas lacunas para que a mesma ocorra.
Âncoras de carreiras e gerações - ingressantes e egressos numa IES
Authors: Maciel Adayne Candido , Monberger Alan Aquino , Dos Reis Thompson Augusto , Cremonezi Graziela Graziano Oste 
Published: September 2018

O propósito deste estudo teve como finalidade correlacionar as gerações e as âncoras de carreiras ilustradas por Edgar H. Schein. As informações estatísticas geradas beneficiaram os membros participantes, a Instituição estudada e as organizações que compõem a Região Metropolitana de Campinas (RMC). A pesquisa fora aplicada em dois grupos de alunos, sendo eles ingressos e egressos do curso de Administração, do Centro Universtiário Adventista de São Paulo (Unasp), em Hortolândia, em que, por meio de 267 alunos, foi permitida a identificação do perfil mais predominante frente às gerações X, Y e Z. Os resultados apresentados indicam que, independente das gerações, a âncora de carreira mais frequente é o estilo de vida, o que apresenta que os futuros profissionais estão em busca de não somente manter uma relação fiel com o mundo profissional, mas também no âmbito famíliar, saúde e lazer — o verdadeiro equilibrista. Para assuntos subsequentes, pode-se abordar as diferenças entre os níveis de perfis dos alunos ingressantes e egressos estudados, e como os fatores sociais podem contribuir para com estes resultados.
“Doing the courses without stopping my life”: Time in a professional Master’s program
Authors: Oliphant Tami , Branch-Mueller Jennifer 
Published: September 2018

This study investigates how time intersects with student learning in Canada’s first, and only, Master of Library and Information Studies (MLIS) in an online teaching and learning stream. Thirty-two students responded to a survey that asked about their experiences, perceptions, and challenges after their first year of the program. Descriptive statistics and NVIVO 10 were used to analyze survey responses and to develop themes through open coding. The findings indicate that time shapes students’ decisions to pursue the MLIS online, their perception of what the degree might mean for their future, their experience in the program, the quality of their relationships, and their learning. The perceived flexibility of the MLIS program was incredibly important to students. However, the majority of students described themselves as “time poor” and many students underestimated the time commitment necessary to complete the program, to manage coursework, and to build and maintain relationships with others.
Rice Aboveground Nitrogen Content, Development, and Yield as Affected by Nitrogen Fertilization and Flood Timing
Authors: Richmond Tyler L. , Slaton Nathan A. , Hardke J. T. , Roberts Trenton L. , Norman R. J. 
Published: September 2018

Delaying fertilizer N and flooding delays maturity of drilled, delayed flood rice.
Delaying the permanent flood may increase uptake of native soil N in some soils.
The optimal preflood N and flood timing window is narrowest on the most N‐deficient soil.

Urea fertilizer is typically applied near the five‐leaf stage to rice (Oryza sativa L.) grown in a dry‐seeded, delayed‐flood production system. How long the preflood N can be delayed without adversely effecting yield is poorly understood. We examined the effects of delaying preflood N application and flooding on rice growth, aboveground N content, heading date, yield components, and grain yield. Trials were established on silt loam soils at the Pine Tree Research Station (PTRS) and Rice Research and Extension Center (RREC) during 2015 and 2016 and included up to five cultivars. Urea was applied at 0, 45, 90, 135, and 180 kg N ha−1 on five to seven different dates with applications beginning near the three‐leaf stage and ranging from 127 to 1035 growing degree units (GDU) among five site‐years (PTRS‐2015a, PTRS‐2015b, PTRS‐2016, RREC‐2015, RREC‐2016). Aboveground N content increased by 25 to 59 kg N ha−1 as N fertilization and flooding were delayed at PTRS‐2015a, PTRS‐2016, and RREC‐2016 due to increased uptake of soil N. Preflood N fertilization and flooding time had no effect on grain yield at the RREC. At the PTRS, relative grain yield of rice receiving no fertilizer N increased from 20 to 41% of the maximum yield as fertilization and flooding were delayed. Maximal relative yield (91%) was produced when fertilization and flooding were performed between 164 and 531 GDU and declined to 62% by 1035 GDU at PTRS. Delaying preflood N fertilization beyond 531 GDU may reduce grain yield on some silt loam soils.
A Global Meta‐Analysis to Predict Atrazine Sorption from Soil Properties
Authors: Ou Ling , Gannon Travis W. , Arellano Consuelo , Polizzotto Matthew L. 
Published: September 2018

Atrazine (2‐chloro‐4‐ethylamino‐6‐isopropylamino‐1,3,5‐triazine) is one of the most widely used herbicides worldwide, and groundwater contamination is of concern, especially in heavily used regions and in edaphic conditions prone to leaching. Soil sorption plays an essential role in atrazine environmental fate, yet consistent atrazine risk prediction remains limited. A quantitative meta‐analysis was conducted to characterize the effect of soil properties on atrazine sorption, using 378 previous observations in 48 publications from 1985 to 2015 globally, which included data on soil properties and sorption parameters. A supplemental regional study was conducted to test the derived meta‐analysis models. The meta‐analysis indicated that percentage organic C (OC) was the most important parameter for estimating atrazine sorption, followed by percentage silt, soil pH, and percentage clay. Meta‐analysis and supplemental study models were developed for Freundlich sorption coefficients (Kf) and sorption distribution coefficients (Kd) as a function of OC. The global meta‐analysis models generated positive linear trends for OC with Kf and Kd (R2 = 0.197 and 0.205, respectively). Organic C was highly correlated with Kf and Kd in supplemental experimental study models (R2 = 0.93 and 0.92, respectively), indicating accurate prediction of sorption within the evaluated region. Continental models were investigated, which improved the goodness of fit. Models developed via meta‐analysis may be used to predict atrazine sorption over wide ranges of data, whereas more accurate and refined prediction can be achieved by specific regional models through experimental studies. However, such models could be improved if standardized agroclimatic conditions, soil classification, and other key variables were more widely reported.Core Ideas
Meta‐analysis quantified soil properties governing atrazine sorption.
Organic C content had the highest correlation with atrazine soil sorption.
Meta‐analysis models showed similar trends to independent experimental results.
Continental and supplemental models improved fit compared with global models.
Standard climate and soil taxonomic data should be reported to optimize models.
A Coupled Soil Water Balance Model for Simulating Depression‐Focused Groundwater Recharge
Authors: Noorduijn Saskia L. , Hayashi Masaki , Mohammed Getachew A. , Mohammed Aaron A. 
Published: September 2018

Core Ideas
Ephemeral ponds in depressions are the foci of groundwater recharge in the Canadian Prairies.
Freeze–thaw processes influence snowmelt runoff and depression‐focused recharge.
A new water balance model was developed to represent these processes.
The water balance model successfully simulated the observed soil processes.
This model will provide a tool to estimate recharge in the prairie landscape.
In arid and semiarid environments, focused infiltration of rain and snowmelt water under topographic depressions is an important mechanism of groundwater recharge. Quantifying the aggregated recharge from numerous small depressions is a major challenge in water resource management. Building on field‐based investigations into the surface water–groundwater interaction of individual depressions and their catchments (i.e., uplands) in the Canadian Prairies, we have developed a simple water balance model to simulate groundwater recharge considering the hydrological coupling of a depression–upland system. The model is based on the Versatile Soil Moisture Budget (VSMB), which has been widely used in the Canadian Prairies to simulate soil moisture conditions. We evaluated the new model, VSMB Depression‐Upland System (VSMB‐DUS), using field data consisting of an artificial flooding experiment and long‐term monitoring of a depression in Alberta, Canada. The model captured surface water level, soil moisture, and groundwater responses to the artificial flooding with reasonable accuracy and represented the interannual variability of recharge fluxes during a 5‐yr period (2007–2011), including dry and wet years. Simulated annual recharge varied between 12 and 45 mm, and annual precipitation varied between 453 and 597 mm during the 5‐yr period. The VSMB‐DUS tends to over‐ or underestimate snowmelt runoff in individual years; however, simulated recharge was only slightly affected by the errors in snowmelt runoff estimation. Due to its computational efficiency and robust algorithms, the VSMB‐DUS will provide a useful tool for estimating aggregated recharge in a large‐scale model grid cell containing hundreds of depression‐upland systems.
Vaginal infections in patients of childbearing age: ways for optimization of treatment in the outpatient setting
Authors: Gorshkova O. V. , Chizhova G. V. , Molodtsova L. Yu. , Morozova O. N. 
Published: September 2018

Despite the considerable success in managing the medical process and medical screening of women of childbearing age, the treatment of vaginal infection remains an urgent problem that requires periodic correction of the prescribed therapy. This made the authors conduct a study, which was aimed at investigating the optimization aspects of the comprehensive therapy regimens for vaginal infections (VI) that combine the use of etiotropic drugs with the extract of Aloe Barbadenis Multi-Gyn ActiGel and systemic enzyme therapy as compared to the prescription of monotherapeutic etiotropic regimen. The study evaluated the effectiveness of different treatment regimens of VIs based on the dynamics of clinical and laboratory parameters, as well as the safety and tolerability of different therapies based on the registration of adverse events.Based on the study results, we would advise to include the plant extract of Aloe Barbadenis Multi-Gyn ActiGel and Wobenzym into the therapy of patients with VIs induced by the vaginal dysbiosis and caused by bacterial vaginosis and candidiasis vulvovaginitis-associated microorganisms to improve the elimination of the pathogen and provide a normal titre of lactobacilli with preservation of their functional activity, which eventually restores the impaired vaginal microcenosis and maintains a normal vaginal flora and simultaneously provides a high safety and good tolerability of the proposed treatment regimen.
ASSESSMENT OF EFFICIENCY OF ANTI-RELAPSE THERAPY WITH DIENOGEST AFTER SURGERY TREATMENT OF WOMEN WITH COLORECTAL ENDOMETRIOSIS
Authors: Lisovskaya E. V. , Chuprynin V. D. 
Published: September 2018

Purpose of research. To analyze reproductive outcomes and relapses of endometriosis in women after surgical treatment of colorectal endometriosis depending on hormonal therapy.Materials and methods. The article includes data on reproductive outcomes and recurrence of endometriosis in women undergoing surgical treatment for colorectal endometriosis in the surgical department of Kulakov National Medical Research Centre for Obstetrics, Gynaecology and Perinatology from 2014 to 2016. As an anti-relapse therapy, the first group of women received dienogest (DNG) at a dose of 2 mg/day, the second group included women who received a combined oral contraceptive containing DNG 2 mg + ethinyl estradiol (EE) 0.03 mg for the period of rehabilitation or prior to planning of pregnancy. The comparison group consisted of women who did not receive hormonal drugs in the postoperative period. Data on side effects and tolerability of the drug are also described.Results. During the follow up period from 12 to 48 months, 51 patients were selected for this study, 14 patients were included in the first group, 18 patients were in the second group, 19 patients were in the comparison group. There were no differences in the overall rate of pregnancy depending on the choice of tactics of postoperative management. The highest number of pregnancies (92.3%) occurred during the first year after surgery, which suggests the effect of the duration of hormone therapy on the probability of pregnancy. The lowest number of relapses was registered in the group of long-term monotherapy of DNG. In the group of DNG monotherapy a greater number of side effects were noted, which in most cases did not cause significant discomfort to patients.Conclusion. Long-term administration of DNG at a dose of 2 mg/day after surgical treatment of colorectal endometriosis is an effective means of preventing relapses with good tolerability. However, in some women planning a pregnancy, it may be rational to abandon hormone therapy in favor of earlier pregnancy planning.