bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrasound is not associated with the presence of systemic autoimmunity or symptoms in individuals at risk for rheumatoid arthritis
Authors: Brulhart Laure , Alpízar-Rodríguez Deshiré , Nissen Michael S , Zufferey Pascal , Ciubotariu Ileana , Fleury Gregory , Lazarou Ilias , Gabay Cem , Finckh Axel 
Published: August 2019

ObjectiveTo identify whether musculoskeletal ultrasound (MSUS) abnormalities are associated with specific phases of rheumatoid arthritis (RA) development in individuals at risk of RA.MethodsThis is a prospective cohort study of individuals at risk of developing RA, namely first-degree relatives of patients with RA (RA-FDRs) without evidence of established rheumatic disease at inclusion. The inflammatory activity on MSUS was assessed according to a validated score (SONAR). Active MSUS was defined as a total B-mode score greater than 8, including at least one joint with significant synovitis (grade 2 or 3) or significant synovial hyperaemia (Doppler score greater than 1). We used logistic regression to analyse associations between MSUS findings and recognised preclinical phases of RA development, adjusting for other demographic and biological characteristics.ResultsA total of 273 RA-FDRs were analysed, of whom 23 (8%) were anticitrullinated protein autoantibodies-positive, 58 (21%) had unclassified arthritis and 96 (35%) had an active MSUS, which was only associated with unclassified arthritis (OR: 1.8, 95% CI 1.0 to 3.3).ConclusionIn individuals at risk of RA, active MSUS was associated with the presence of unclassified arthritis, but not with any of the earlier described phases of RA development. These findings do not support an indiscriminate use of ultrasound in a screening strategy for preclinical RA.
Peningkatan Stabilitas Lereng Lapisan Tanah Liat Penahan Lindi TPA dengan Penambahan Limbah Bangunan
Authors: Budihardjo Mochamad Arief 
Published: August 2019

Liner merupakan komponen terpenting dalam fasilitas tempat pengolahan akhir (TPA) sampah untuk mencegah lindi mencemari tanah. Bahan yang sering digunakan sebagai liner adalah tanah lempung yang memiliki permeabilitas rendah. Salah satu tanah lempung alami yang dapat digunakan sebagai liner TPA adalah bentonit. Bentonit memiliki permeabilitas yang sangat rendah, namun stabilitas gesernya tidak begitu kuat sehingga berpotensi mengalami keruntuhan apabila digunakan di daerah lereng.Di sisi lain, limbah bangunan yang berupa pecahan batu bata, campuran pasir dan semen, serta beton memiliki kuat geser yang tinggi dan berpotensi sebagai campuran bentonit. Pada penelitian ini, limbah bangunan sebanyak 5%, 10%, dan 15% ditambahkan pada bentonit untuk meningkatkan kekuatan geser bentonit sehingga didapatkan campuran bahan semi kedap dengan stabilitas yang lebih tinggi dan permeabilitas rendah. Hasil uji stabilitas geser yang dilakukan pada tegangan normal 50 kPa , 100 kPa, dan 200 kPa menunjukkan bahwa semakin meningkatnya konsentrasi campuran bahan bangunan, maka semakin meningkat pula nilai tegangan geser yang dihasilkan
Zinc deficiency in Japanese children with idiopathic short stature
Authors: Yoshida Kei , Urakami Tatsuhiko , Kuwabara Remi , Morioka Ichiro 
Published: August 2019

Abstract

Background and methods
We investigated the frequency of zinc deficiency in Japanese children with idiopathic short stature, and evaluated whether serum zinc levels correlated with background factors, including age and standard deviation scores (SDSs) for height and serum insulin-like growth factor (IGF)-1 levels. The study subjects consisted of 89 Japanese children.

Results
The mean serum zinc level was 79 ± 12 (49–108) μg/dL. Of all the children, 48.3% had a low zinc level, in the 60–80 μg/dL range, and 6.7% had zinc deficiency with a zinc level below 60 μg/dL. The majority with a low zinc level and zinc deficiency were asymptomatic other than for short stature. We found no significant correlations of serum zinc with age, or the SDSs for height and serum IGF-1 levels, in either the entire subject population or those with a zinc level below 80 μg/dL.

Conclusions
We found a low zinc level to be common in Japanese children with idiopathic short stature, whereas actual zinc deficiency was rare. However, other as yet unknown mechanisms not associated with the growth hormone (GH)-IGF-1 axis could be involved in growth retardation in idiopathic short stature.
Late Pleistocene and Holocene distribution history of the Eurasian beaver in Italy
Authors: Salari Leonardo , Masseti Marco , Silvestri Letizia 
Published: August 2019

Abstract
The genus Castor first appeared in the Palaearctic region during the Late Miocene, while the current species, Castor fiber, is widely accepted to have emerged in the Early Pleistocene. In the Last Glacial Maximum (Late Pleistocene), the beaver disappeared from most of the Western Palaearctic, only surviving in a few relic areas including the south-eastern Alpine Chain as shown by new data. After the subsequent extended repopulation in the warmer phases of the Lateglacial and in the early Holocene, the species once again disappeared locally from several countries, including Italy, between the 17th and the 20th centuries. Direct or indirect persecution by humans seems to be the main cause of beaver extinction in Europe. In Low Medieval Italy, it is more likely that the disappearance of the beaver between the 16th and 17th centuries was due to habitat alteration and human population pressure. Numerous reclamations have been carried out since the late Middle Ages, mostly in the easternmost area of the Po Valley, the last beaver refuge in Italy. Eurasian beaver was common in the northern and widespread in the central part of Italy, but always absent in southern Italy, probably due to unfavourable hydrological conditions of watercourses in the latter.
Green marketing orientation: evolution, conceptualization and potential benefits
Authors: Vilkaite-Vaitone Neringa , Skackauskiene Ilona 
Published: August 2019

Abstract
Global economic fluctuation, post-Brexit challenges, changes in the landscape of corporate social responsibility are pushing managers to build sustainability into the performance of marketing mix. Traditional marketing is no longer able to address all the issues in modern markets. This led to green marketing, a new marketing philosophy. The paper provides researchers and marketing managers with a comprehensive view of the concept of green marketing, its causes, contents, and outcomes. Authors suggest a structured and outcome-based viewpoint to the construct of green marketing. Theoretical presumptions confirm structuration of green marketing initiatives to strategic, tactical, and operational levels. It was found out that cohesive marketing activities in these levels have the crucial impact of green marketing in organizational, environmental, and social contexts. Strategic, tactical, and operational activities in the field of green marketing may lead to business development, improvement of the natural ecosystem, and increased quality of life. The findings of the research present opportunities for researchers and managers to apply green marketing orientation.
Untersuchungen an Systemen des Typs PCl3/MCl3/Aren (M = Al, Ga), I. Reaktionen mit Monohalogenbenzolen; Multikern-NMR-spektroskopische Charakterisierung von Aryldichlorhydrogenphosphoniumsalzen; Struktur des para-Fluorphenyldichlorphosphonium-tetrachloroaluminats
Authors: Frank Walter , Gelhausen Björn , Reiß Guido J. , Salzer Risto 
Published: August 2019

AbstractThe reactions of the monohalobenzenes with AlCl3 (GaCl3) and PCl3 have been monitored by 31P NMR spectroscopy. Primary product of the reaction with fluorobenzene and AlCl3 is the thermolabile para-fluorophenyldichlorophosphonium tetrachloroaluminate, which was characterized by 1H, 13C, 19F, 27Al and 31P NMR spectroscopy as well as by a crystal structure analysis (space group P21/c, a = 7.0720(10), b = 12.659(3), c = 15.413(3) Å, ß = 90.93(3)°, Z = 4, T = -110 °C). For the phosphonium ion we found a very good agreement of the experimental structural parameters and those obtained by ab initio quantum chemical calculations at the B3LYP 6-31++G(d,p) level of theory. Both, the experimentally determined and the calculated structure show a significant chinoid distortion of the para-disubstituted benzene ring. From the primary product the reaction proceeds to give exclusively para-fluorophenyl-(phenyl)dichlorophosphonium tetrachloroaluminate. With GaCl3 and fluorobenzene analogous tetrachlorogallates were observed, however, some by-products were recognized: para-ftuorophenylchlorofluorophosphonium and para-fluorophenyldifluorophosphonium tetrachlorogallate at the beginning of the reaction, bis(para-fluorophenyl)chlorophosphonium tetrachlorogallate at a later stage of the reaction. The reaction of chlorobenzene with PCl3 and AlCl3 yields analogous products as compared to the reaction with fluorobenzene. However, appreciable amounts of ortho- and some meta-chlorophenyldichlorophosphonium tetrachloroaluminate are by-products. If GaCl3 is used instead of AlCl3, numerous by-products and reaction intermediates are detectable. The major one is para-chlorophenyldihydrogenchlorophosphonium tetrachlorogallate. No principal differences were observed, when AlCl3 and GaCl3, respectively, reacted with bromobenzene and PCl3 giving phenylbromodichlorophosphonium and para-bromophenylbromodichlorophosphonium salts as well as some amounts of the ortho- and meta-bromophenyl derivatives. With iodobenzene the corresponding reactions exclusively give phenyldichloroiodophosphonium tetrachloroaluminate and -gallate, respectively.
REUNIÃO CLÍNICA INTERDISCIPLINAR - UMA ESTRATÉGIA DE ENSINO BASEADA EM PROBLEMAS NA GRADUAÇÃO EM FISIOTERAPIA: RELATO DE EXPERIÊNCIA
Authors: Fernandes Susi Mary de Souza , Rodrigues Étria , Graciani Zodja , Fernandes Marcelo , Salerno Gisela Rosa Franco , Vianna Denise Loureiro 
Published: August 2019

Atualmente busca-se um modelo de ensino superior inovador, capaz de capacitar os profissionais para responder demandas de saúde da sociedade. O Curso de Fisioterapia de uma universidade privada de São Paulo propõe nas diretrizes curriculares, consignada ao Projeto Pedagógico Institucional e às Diretrizes Nacionais para Cursos de Graduação em Fisioterapia, um currículo no qual as disciplinas são oferecidas obedecendo uma estrutura longitudinal de complexidade crescente e, metodologias ativas de ensino desenvolvidas em diferentes estratégias de ensino como: estudo de caso, solução de problemas e painel inseridos em todas as disciplinas do curso e concretizados no encontro de apresentação designado Reunião Clínica Interdisciplinar (RCI). A RCI tem se constituído como uma ferramenta de motivação, instrumentalização e capacitação dos professores, e proporcionado aos alunos o desenvolvimento de habilidades de argumentação, coerência e síntese, correlação teórico prática, postura profissional crítica e reflexiva observadas principalmente, nos alunos das últimas etapas.
QUALIDADE DE SONO E SUA RELAÇÃO COM FADIGA EM INDIVÍDUOS COM ESCLEROSE MÚLTIPLA
Authors: Luteski Bianca , Brandalize Danielle , Rossi Luciano Pavan , Brandalize Michelle 
Published: August 2019

Introdução: Oitenta por cento dos indivíduos com Esclerose Múltipla (EM) apresentam fadiga, a qual costuma ser um dos sintomas mais debilitantes. Além disso, problemas relacionados ao sono também são comuns nesses indivíduos. Objetivo: Verificar a relação entre qualidade de sono e fadiga em indivíduos com EM. Método: Dez indivíduos de ambos os sexos com idade média de 35.0 ± 8.77 anos com diagnóstico de EM do tipo remitente-recorrente e que apresentavam fadiga pela escala de severidade da fadiga (≥28) participaram do estudo. Os instrumentos utilizados foram o Índice de Qualidade do Sono de Pittsburgh (IQSP) e Escala Modificada de Impacto da Fadiga (MFIS), a qual avalia os efeitos da fadiga nas funções físicas, cognitivas e psicossociais. A duração de sono, a siesta e sonolência diurna foram obtidos através do auto-relato. Resultados: 70% dos participantes apresentaram qualidade de sono ruim (IQSP >5), as médias de duração de sono foram maiores nos finais de semana (9,6h) quando comparados aos dias de semana (7,8h). Todos os participantes relataram sonolência diurna e 90% relataram o hábito da siesta. Não houve correlação entre qualidade de sono e o escore total da fadiga (MFIS) (r=0.23, p=0.51), porém foi observada correlação entre qualidade de sono e o dominio fadiga psicossocial (r=0,69, p=0,026). Conclusão: Não houve correlação entre qualidade de sono e escore de fadiga total, entretanto, as formas de compensação do sono como a siesta podem ter influenciado nesse resultado. Contudo, houve correlação moderada entre qualidade de sono e fadiga psicossocial.
O Judiciário e a demarcação de terras indígenas: o caso de Pernambuco
Authors: Maia Fernando Joaquim Ferreira , Souza Júnior Gilberto Romeiro de 
Published: August 2019

Resumo: Neste artigo trata-se dos conflitos envolvendo terras indígenas em Pernambuco pelo Judiciário. A análise foi feita a partir das decisões em Pernambuco e que tratam dos processos de conflitos de terras indígenas. No estudo empregam-se as noções do direito do acesso à terra e o posicionamento dos juízes na resolução dos conflitos envolvendo terras indígenas. Analisa-se a atuação da jurisdição diante das questões de terras indígenas, bem como investigam-se os possíveis cenários desses conflitos no Estado. Utilizaram-se como instrumentos de pesquisa livros e artigos de Direito e Sociologia sobre conflitos ambientais sobre apropriação de terras, e as decisões judiciais acerca dos conflitos pelo direito à terra nas comunidades indígenas. Defende-se que o Judiciário age de forma incoerente ao aplicar a norma material ambiental nos conflitos envolvendo as terras indígenas. Portanto, os povos indígenas não encontram no Judiciário um campo favorável para defesa dos seus direitos relativos à terra. Palavras-chave: Análise judicial. Direito à terra. Indígenas. Conflito.
MODEL KEPEMIMPINAN CARE GROUP DALAM PENDIDIKAN HOLISTIS [A LEADERSHIP MODEL OF CARE GROUPS IN HOLISTIC EDUCATION]
Authors: Tjhin Nico Tanles , Hidayat Dylmoon 
Published: August 2019

<p>A study program at a private higher education institution, namely CT, a transformational holistic education organization, implements an academic and non-academic guidance program through small groups called CARE Groups (CG). However, regardless of there being a CG program, there are still many cases of CT students breaking rules. These range from general cases to more severe ones that result in warning letters. The discrepancy found in the range of cases is the topic of this study, which focuses on the perspective of the CG leadership. The qualitative method of case study was utilized so that the data may be accurate and in-depth for analysis, in order for there to be further discussion. The three main findings that answered the problem formulated in this study were the description of strategies and CT efforts in equipping CG Leader (CGL), an explanation of the reasons for the emergence of cases among students, and the formulation of an ideal profile for a CGL.</p><p><strong>BAHASA INDONESIA ABSTRAK:</strong> Sebuah program studi di suatu perguruan tinggi swasta, sebut saja CT, suatu lembaga pendidikan holistis yang transformasional menerapkan suatu program bimbingan akademik dan non-akademik berbentuk kelompok kecil bernama <em>CARE Group</em> (CG). Namun, terlepas dari adanya instrumen CG, kasus pelanggaran peraturan di kalangan mahasiswa CT kerap kali muncul, mulai dari kasus umum sampai kasus berat yang memiliki konsekuensi Surat Peringatan (SP). Kesenjangan tersebut menjadi topik pembahasan dalam studi ini, berfokus pada segi pandangan kepemimpinan CG. Metode penelitian kualitatif studi kasus digunakan agar mendapatkan data yang akurat dan mendalam untuk dianalisis dan dibahas lebih lanjut. Diperoleh tiga temuan utama yang menjawab rumusan masalah dari penelitian ini, yaitu deskripsi strategi dan upaya CT dalam memperlengkapi CG Leader (CGL), penjelasan akan alasan masih munculnya kasus di kalangan mahasiswa, dan rumusan sebuah profil ideal bagi seorang CGL.</p>
Neonatal sepsis and its associated factors in East Africa: a systematic review and meta-analysis, 2019
Authors: Abate Biruk Beletew , Kasie Ayelign Mengesha , Kassaw Mesfin , Getu Mikiyas Amare 
Published: August 2019

Abstract
Background : Neonatal sepsis is one of the leading causes of inflated death and illness of neonates. Different primary studies in Eastern Africa showed the burden of neonatal sepsis. However, inconsistency among those studies was seen and no review has been conducted to report the amalgamated magnitude and associated factors. Therefore, this review intended to estimate the national prevalence and associated factors of neonatal sepsis in Eastern Africa. Methods : Using PRISMA guideline, we systematically reviewed and meta-analyzed studies that assessed the prevalence and associated factors of neonatal sepsis from PubMed, Cochrane library, and Google Scholar. Heterogeneity across the studies was evaluated using the Q and the I 2 test. A weighted inverse variance random-effects model was applied to determine the prevalence and the effect size of associated factors. The subgroup analysis was done by country, study design, and year of publication. A funnel plot and Egger’s regression test were used to see publication bias. Result : A total of 26 studies with 11239 participants were used for analysis. The pooled prevalence of neonatal sepsis in East Africa was 29.65% (95% CI; 23.36–35.94).Home delivery(AOR =2.67; 95% CI: 1.15-4.00; I 2 = 0.0%; P=0.996), maternal history of UTI (AOR=2.083; 95% CI :0.24-3.93; I 2 = 69.1%; P=0.001),gestational age (preterm) (AOR=1.56; 95% CI: 1.04-2.08; I 2 = 27.8%;P=0.000) ,prolonged labor (AOR=3.23 ;95% CI: -0.04-6.51; I 2 = 62.7%; P=0.020) and PROM (AOR= 1.95; 95% CI: 0.53-3.37; I 2 = 43.2%; P=0.062) were identified factors of neonatal sepsis. Conclusions : The prevalence of neonatal sepsis in Eastern Africa remains high. This review may help policy-makers and program officers to design neonatal sepsis preventive interventions.
Pain Mechanisms in Low Back Pain: A Systematic Review With Meta-analysis of Mechanical Quantitative Sensory Testing Outcomes in People With Nonspecific Low Back Pain
Authors: den Bandt Hester L. , Paulis Winifred D. , Beckwée David , Ickmans Kelly , Nijs Jo , Voogt Lennard 
Published: August 2019

Background Mechanical quantitative sensory testing (QST) assesses sensory functioning and detects functional changes in (central) nociceptive processing. It has been hypothesized that these functional changes might be apparent in people with nonspecific low back pain (LBP), although the results are mixed. Objective The aim of this systematic review was to examine whether sensory function, measured with QST, was altered in people with nonspecific LBP. Methods This systematic review was conducted according to PRISMA guidelines. Six databases were searched for relevant literature. Studies comparing mechanical QST measures involving people with subacute and chronic LBP and healthy controls were included if (1) pressure pain thresholds (PPTs), (2) temporal summation, or (3) conditioned pain modulation were reported. Risk of bias was assessed using the Newcastle-Ottawa scale. When possible, the results from different studies were pooled. Results Twenty-four studies were included. Scores on the Newcastle-Ottawa scale varied between 1 and 6 points. People with nonspecific LBP, compared to healthy controls, had significantly lower PPTs at remote sites and increased temporal summation at the lower back. The PPTs measured at the scapula were significantly lower in patients with nonspecific LBP than in healthy controls (pooled mean difference, 119.2 kPa; 95% confidence interval: 91.8, 146.6 kPa; P<.001). Conclusion The PPT measurements at remote body parts were significantly lower in people with nonspecific LBP compared with healthy controls. Temporal summation and conditioned pain modulation measurements had mixed outcomes. Level of Evidence Therapy, level 3a. J Orthop Sports Phys Ther 2019;49(10):698–715. Epub 23 Aug 2019. doi:10.2519/jospt.2019.8876
STRATEGI PENGUATAN INSTITUSI PENDIDIKAN TINGGI AGAMA ISLAM INDONESIA: TELAAH HISTORIS TRANSFORMASI FA-UII KE PTAIN ERA MENTERI AGAMA K.H. A. WAHID HASYIM
Authors: Abror Darul 
Published: August 2019

This paper aims to discuss the politics of strengthening Islamic higher education institutions Era Minister of Religion K.H. A Wahid Hasyim which has never been studied by anyone. So this study becomes important to do. This paper uses "Interest Groups Theory" which has been incorporated in The Politics of Education Association (PEA) as its analytical tool so that it is relevant to the context of the discussion. The researcher uses the qualitative method "Library Research" with an educational political approach with a historical style. In this paper there are two important findings, First, the emergence of programs to strengthen Islamic higher education institutions in Indonesia on the basis of the construction of internal and external factors, namely the existence of praxis "Draw Motives" by using a rational and spiritual approach that is emphasized in the concept and practice. Second, in practice, is that the interaction pattern used by the Ministry of Religion KHA Wahid Hasyim in the process of strengthening Islamic higher education institutions in Indonesia is an interaction pattern of "Accommodative Compromising Associative".
Abstrak
Tulisan ini bertujuan untuk membahas tentang politik penguatan institusi pendidikan tinggi Islam Era Menteri Agama K.H.A. Wahid Hasyim yang belum pernah diteliti oleh siapapun. Sehingga kajian ini menjadi penting untuk dilakukan. Tulisan ini menggunakan “Interest Groups Theory” yang sudah tergabung dalam The Politics of Education Association (PEA) sebagai pisau analisisnya sehingga relevan dengan konteks pembahasan. Metode dalam penelitian ini menggunakan metode kualitatif “Library Reseach” dengan pendekatan politik pendidikan dengan corak historis. Sedangkan dalam pengumpulan data diperoleh melakukan studi dokumentasi dan wawancara, dan teknik analisa data yang digunakan dengan teknik analisis kualitatif melingkar dengan memerikan, menggolongkan dan menggabungkan. Dalam tulisan ini terdapat dua temuan penting, Pertama, munculnya program penguatan institusi pendidikan tinggi Islam di Indonesia atas dasar konstruksi faktor internal dan eksternalnya adalah adanya praksis “Motif Imbang” dengan menggunakan pendekatan rasional dengan spiritual yang ditegaskan dalam konsep dan praksisnya. Temuan kedua, pada praksisnya, pola interaksi yang digunakan era Menteri Agama K.H. A. Wahid Hasyim dalam proses penguatan institusi pendidikan tinggi Islam di Indonesia adalah pola interaksi “Asosiatif Akomodatif Kompromistis”.