bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of Immune thrombocytopenic purpura during pregnancy: A single center experience
Authors: Poudyal B.S. , Sampurna T. , Neupane S. , Shrestha P.R. , Chitrakar N. , Pariyar J. , Maharjan K.K. , Mishra Rupesh 
Published: May 2019

Background: Immune thrombocytopenic Purpura (ITP) is the second most common cause of an isolated low platelet count during pregnancy. It account for about 3% of thrombocytopenic cases during delivery. Treatment is indicated, if there is an evidence of bleeding or platelet count is less than 30,000/µl. Herein, we presented a medical record of twenty-four pregnant women, who were diagnosed with ITP during pregnancy.
Method: A total number of twenty four pregnant women diagnosed with primary ITP and having platelet count of less than 30000/µl were enrolled in the study. Oral prednisolone (1mg/kg) was started in all patients with an aim to keep the platelet count above 50000/µl during delivery. Steroid was continued for 21 consecutive days and were tapered (10 mg) every week, if platelet counts were above 30000/µl.
Data pertaining to the ITP during pregnancy was recorded for age, platelet count, mode of delivery and complications related to steroid therapy and were analyzed by simple statistical analysis.
Result: ITP was observed in about 58%, 25% and 17% of the cases during first, second and third trimester respectively. About, 63% of patients presented with purpuric rash, 18% presented with mucosal bleed, one present presented with hematuria and others were asymptomatic. More than two third of cases responded to the steroid and in those cases platelet counts were above 50,000/µl at the time of delivery. All subjects delivered a healthy child. There was no maternal mortality and post-partum hemorrhage was absent in all patients.
Conclusion: Steroid is the treatment of choice for all cases of ITP. ITP is no longer a contraindication to the continuation of pregnancy, the tradition and tendency to advice for abortion in these pregnant mothers, may not be justifiable.
Delivery Profile and indications of Cesarean Section in a rural referral Hospital: what could be the implications?
Authors: Shrestha U. , Aryal Binod 
Published: May 2019

Introduction: There is huge difference in cesarean section rate between rural (3.5%) and urban (15%) areas of Nepal. The national CS rate is around 5% whereas global CS rate is 26%. The objective of this study is to find out the delivery profile and rate and indications of CS in a rural university hospital.
Methodology: This is a three -year’s retrospective cross-sectional study done from January 2016 to January 2019 (Magh 2072 to Poush 2075) at Karnali Academy of Health Sciences, Jumla. The data was retrieved from hospital birth profile records and analyzed using SPSS 20. Permission was taken from Institutional review committee (IRC) to conduct the study.
Results: Total number of delivery during this period was 1841 out of which 172 were Cesarean delivery giving a CS rate of 9.3%. The most common indication of CS were fetal distress (33.7%), previous CS (9.3%), failed induction of labor (9.3%). Non progress of Labor (8.1%) and post term pregnancy (8.1%). Majority of the CS were done as an emergency procedure.
Conclusion: The CS rate at KAHS teaching hospital was within WHO recommendation of between 5-15% and was very low in comparison to other centers situated in urban areas of the country. The indications of CS was also similar to the other national and international statistics.
Utilization of Family Planning Services in Karnali Academy of Health Science, Jumla
Authors: Shrestha Sharmila , Chaulagain S. , Pandey K. 
Published: May 2019

Introduction: Family planning is an integral part of maternal health as its uptake is a significant factor in the reduction of maternal mortality and in ensuring positive child health outcomes specially in developing countries, however, its usage remains low.
Objectives: To describe prevalence and pattern of contraceptive use, among women accessing family planning facilities.
Study design: A retrospective review of hospital records of family planning clinic clients at the teaching hospital was conducted.
Results: Total 2811 clients accepted a family planning service during the period. Contraceptive prevalence rate was 21%. Modal age group of clients (81%) was below 20 years old. Injection Depo was the most common method (69%) and implant was less used method (8%) among the temporary method of family planning.
Conclusion: There is an identified need for promotion of uptake of family planning methods. Involvement of young women, uneducated women and men in contraception counseling and services is essential to improve its uptake and continuity.
Comprehensive Emergency Obstetrical and Neonatal Care (CEmONC) at Karnali Academy of Health Sciences, Teaching Hospital, Jumla
Authors: Bhattarai Saraswoti Kumari Gautam , Dahal M. 
Published: May 2019

Introduction: Providers skilled in emergency obstetric and newborn care (EmONC) services are essential, particularly in countries like Nepal with a high burden of maternal and newborn mortality. So this study aims to find out the status of comprehensive emergency obstetrical and neonatal care (CEmONC) service.
Method: A retrospective cross-sectional study was conducted using secondary data sources at maternity ward of KAHS teaching hospital, Jumla. Total 291 women admitted in maternity ward for childbirth were included in the study of six month period of 2075. Sampling technique was census for the study who were admitted for child birth purpose. Cases were selected from the record of the maternity ward. The data was collected by using structured tool. Ethical approval was taken from the ethical review committee of KAHS for ethical clearance. Data was analyzed by using descriptive statistics.
Result: There were 291 women admitted in the maternity ward for the purpose of childbirth during six-month period. Among them 224(76.97%) women delivered baby by spontaneous vaginal delivery; 61(20.96%) delivered with C/S and 6(2.06%) were delivered with instrumental delivery. Regarding the indication of 61 cesarean section (C/S) delivery; 22.95% with fetal distress, 16.39% with cephalopelvic disproportion and 11.47% with meconium stained liquor
Conclusions: About one third childbirth was done by cesarean section with indication of fetal distress, cephalo-pelvic disproportion and meconium stained liquor in higher proportion. Although CEONC service is effective, the rate of cesarean section can be reduced by providing good quality antenatal care.
Health scenario of Karnali Province
Authors: Paudel Tarun , Amgain K. , Sanjel S. 
Published: May 2019

Introduction: Although Karnali is an old civilization of Nepal, this province has low human development indexes and the indicators of health are low. This study was carried out to comprehend the trend of public health indicators and disease pattern of Karnali Province.
Methods: Descriptive study using provincial three years’ health data were reviewed from all the 10 districts of Karnali Province using per forma. Data entered in Microsoft Excel software were transferred into the statistical package for social sciences version 21 and descriptive analysis was carried out.
Results: Previous three years’ data were analyzed. The last years’ results were BCG coverage was 106.0%, DPT/Hepa B was 93.0%, 95.0%, tetanus toxoid (TT) 2 & tetanus toxoid 2+ was 82.0%, 0-11 months' growth monitoring was 126.0%, 0-23 months' underweight children was 8.0%, pneumonia among new acute respiratory infection was 24.0% prevalence of acute respiratory infection was 949/1,000, prevalence of diarrhea was 709/1,000 and severe dehydration among diarrhea was 0.9%. Four Antenatal chick up was 55.0% institutional delivery was 67.0%, delivery by skill birth attendant was 56.0%, health examination within 24 hours of delivery was 65.0%, and contraceptive prevalence (CPR) rate was 35.0%. Likewise, treatment success rate of tuberculosis was 86.0%, new case detection for rate/100,000 tuberculosis was 0.5, HIV Incidence rate/10,000 was 5.3 and outpatient department attendance was 83.0%. Among top 10 diseases, respiratory infection was the first with 14.8%, followed by acute peptic disorders 10.4%, headache 7.9%, worm infestations 7.2% and fall injuries/ fractures found 5.9%.
Conclusions: The indicators of health condition of Karnali Province are markedly low in comparison to the other provinces as well as the national figure. The utilization of public health services has to be reinforced in the province and districts.
Complex partial seizure with postictal aggression as a presentation of atypical eclampsia: a case report
Authors: Agrawal Pawan Kumar Bajaj , Gauchan B. , Dhungana S.K. , Wong L. 
Published: May 2019

Background: Complex partial seizure with sudden onset in near term pregnancy can be challenging to the attending clinician and it is essential to proceed with a presumptive diagnosis of eclampsia, especially in resource poor settings. Unlike generalized tonic clonic seizures, which are more common in eclampsia, complex partial seizures may not jeopardize the fetus with the same severity. However the associated postictal aggression manifested in self-inflicted trauma poses an imminent risk onto the fetus.
Case presentation: A nineteen year old gravida two para one living zero woman presented with seizure at thirty six weeks and three days of gestation in a district hospital. The blood pressure recordings during her entire pregnancy were normal and proteinuria was not present. Her previous pregnancy had a similar course, with self-inflicted trauma to her abdomen in a postictal state and resulted in loss of fetus. She did not have any seizures in between then and the current admission. While being managed in the labor ward, the family physicians witnessed complex partial seizure with postictal aggression. The delivery was expedited with caesarean section and she had no further seizure activity.
Conclusion: Complex partial seizures with postictal aggression in pregnancy are rare but can be an atypical presentation of eclampsia and poses a diagnostic dilemma to the clinician.
Effect of steel casting speed mode on quality of continuously casted billet
Authors: Stolyarov A. M. , Retunskaya A. M. , Potapov M. G. , Potapova M. V. 
Published: May 2019

The speed of billet withdrawal from a continuous caster (CC) mold has a decisive effect on the CC productivity. However, increase of the speed results in an increase of pollution of the CC metal by non-metallic inclusion and increase of surface defects of CC billet. Estimation of steel casting speed mode impact on the degree of different defects formation presented for long products CC billets, casted at a five-strand CC of radial type. Defects of CC billet from Ст3сп steel grade studied for a billet having section of 150×150 mm. The purpose of the study was to determine the degree of influence of withdrawal speed, metal chemical composition and billets cross section dimensions on billets quality. Array of industrial data of more than 550 billets studied, 80.4% of which were casted by an open stream and the balance – by a closed stream. As a result of the CC billets quality study it was confirmed, that during metal casting by an open stream the degree of evolution of form defect, like rhombic defects, internal and surface defects is higher comparing with those when casting by a closed stream. General tendency of increase of the CC metal pollution by non-metallic inclusions at the increase of billet withdrawal speed. The tendency is similar for both casting by an open and by a closed stream. However, during casting by an open stream the increase takes place rather evenly. During casting by a closed stream a sharp increase of billets with defects were observed at the billets withdrawal speed exceeding 2.4 m/min. Linear dependencies of billets withdrawal speed while casting by a closed stream on the degree of liquation cracks evolution and general strips, edge point pollutions and peripheral fine structure metal zone thickness determined. To improve the long products billets surface, casted by a closed stream, it was recommended to restrict the withdrawal speed of the billet from a carbon steel of general quality by the value of 2.4 m/min.
Elaboration of a technology of long rail lashes production without induction heat treatment application
Authors: Kozyrev N. A. , Shevchenko R. A. , Krat’ko S. N. , Kryukov R. E. , Mikhno A. R. 
Published: May 2019

Welding butts of rail lashes after resistance butt-welding are subjected to heat treatment to eliminate heat-affected zones. At present facilities of induction heating are used in Russia for the heat treatment and compressed air as a quenching media. However, this method of quenching has significant drawbacks, including appearance of new heat-affected zones at the local heating of the welded butts, deterioration of the welded butts’ straightness after cooling. Shlatter Company proposed a solution of this problem by application of the process of resistance butt-welding by rails fusion. Theoretical calculations and laboratory studies of the thermal cycle of rail steel samples welding were made in the Siberian State Industrial University, which showed a principal possibility of this method application under industrial conditions. The method assumes after the welded butt settling and cooling to keep the preset temperature from the moment of its reaching by passing alternative electric current pulses through the welded butt. The temperature of exposure is selected based on obtaining necessary fine grain seam metal structure. The duration of exposure is determined by latency period of the structure formation and is controlled by the number of current pulses. The carried out industrial experiments at the МСР-6301 resistance butt welding machine resulted in determining parameters of cooling time after settling, heating and cooling after the heating, as well as the number of heating pulses. A method of resistance butt welding was tested, enabling to obtain the welded joint of details of the P65 ДТ350 category rail steel. The welded joint had mechanical properties exceeding technical requirements of СТО РЖД 1.08.002–2009 specifications.
COMPARISON OF THE EFFECT OF FOREIGN DEBT ON ECONOMIC GROWTH OF INDONESIA IN THREE PERIODS OF GOVERNMENT
Authors: Ningsih Endang Kusdiah , Naruliza Esty , Mario Asma 
Published: May 2019

This purpose of this articel is to determine the ratio of the effect of foreign debt on economic growth. Since the reign of the Old Order up to the reign of the Reform Order to date, the Indonesian government has always done debt (overseas loans). So as if the growth that accomplished by the Indonesian economy each year can not be separated from foreign debt.The data used are secondary data obtained from the Central Bureau of Statistics and Bank Indonesia. The analysis technique to be used is Quantitative Descriptive Method. The results of hypothesis test show that the effect of foreign debt on economic growth only during the Reform Order.
PENGARUH BUDAYA ORGANISASI DAN MOTIVASI KERJA TERHADAP KINERJA KARYAWAN PADA BANK MANDIRI CLUSTER PAMULANG
Authors: Nurdina Anisa 
Published: May 2019

ABSTRAK Yang melatar belakangi permasalahan dalam penelitian ini adalah rekapitulasi absen karyawan periode januari sampai desember di cluster Pamulang yang masih cukup tinggi tingkat absensinya. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh budaya organisasi dan motivasi kerja secara bersama-sama (simultan) terhadap kinerja karyawan. Metode yang digunakan dalam penelitian ini adalah metode Survey dengan bentuk koresional . Populasi dalam penelitian ini adalah 110 karyawan dengan sampel sebanyak 87 karyawan yang diambil dengan menggunakan teknik Simple Random Sampling. Analisis data yang digunakan adalah analisis korelasi ganda dan regresi ganda dengan bantuan komputer Apikasi SPSS 17. Hasil penelitian menunjukkan, budaya organisasi berada pada kategori cukup kuat sama seperti motivasi kerja dan kinerja. Harga koefisien regresi dalam penelitian ini Ho ditolak dan Ha diterima, artinya budaya organisasi dan motivasi kerja berpengaruh signifikan terhadap kinerja karyawan pada Bank Mandiri Cluster Pamulang, serta memiliki pengaruh 31,47% terhadap kinerja karyawan sisanya 68,53% dipengaruhi oleh faktor-faktor lainnya.Kata Kunci : Budaya Organisasi, Motivasi Kerja, Kinerja Karyawan
PERBANDINGAN TINGKAT EFISIENSI BANK SKALA BESAR DAN SKALA KECIL
Authors: LISDAWATI LISDAWATI 
Published: May 2019

ABSTRAKTujuan penelitian ini adalah untuk melihat apakah tingkat efisiensi bank berskala besar dan skala kecil berbeda secara signifikan, untuk mendapatkan gambaran umum tentang tingkat efisiensi pada industri perbankan, juga bertujuan untuk membandingkan efisiensi perbankan berskala besar dan kecil yaitu masing masing terdiri dari 5 bank .Alat analisis yang digunakan yaitu rasio-rasio perbankan dan uji beda. Hasil penelitian ini menunjukan nilai BOPO bank skala besar berada pada 60% – 90 % sedangkan nilai BOPO bank skala kecil berada antara 70% – 90%. Hal ini menunjukan bahwa secara umum bank skala kecil mengalami unefisiensi. Dengan menggunakan uji beda menunjukan adanya perbedaan yang signifikan antara bank skala kecil dan bank skala besar.Kata Kunci : Bank Skala Besar, Bank Skala Kecil, Efisiensi.
ANALISIS KEPUASAN JAMA’AH PADA KINERJA DEWAN KEMAKMURAN MASJID AL-HIDAYAH PERIODE TAHUN 2017
Authors: Pasaribu Veta Lidya Delimah , Krisnaldy Krisnaldy , Senen Senen 
Published: May 2019

ABSTRAK Penelitian ini bertujuan Untuk pemahaman tentang bagaimana mengembangkan dan mengelola masjid, sehingga lebih banyak berperan dalam mengatasi problem umat dan masyarakat. serta memberikan gambaran umum tentang kemakmuran umat dan masyarakat melalui sebuah manajemen organisasi berbasis, Penelitian ini akan dilaksanakan dalam waktu kurang lebih 6 (enam) bulan sejak ditanda tanganinya kontrak perjanjian penelitian. Sebagai lokasi penelitianya di Masjid AL-HIDAYAH, yang beralamatkan di Jl. Anggur V Pamulang Permai I,Blok A35-A50 Kelurahan Pamulang Barat.Kecamatan Pamulang.Tangerang Selatan.Dalam penelitian ini proses pengumpulan data menggunakan 3 (Tiga) metode pokok yang saling berkaitan dan melengkapi, yaitu; Metode Wawancara Metode wawancara merupakan metode pengumpulan data dengan jalan komunikasi, yakni melalui kontak atau hubungan pribadi anatara pengumpul data (pewawancara) dengan sumber data (responden) Dalam penelitian ini juga , foto yang akan digunakan adalah foto pribadi yang dihasilkan oleh peneliti sendiri pada saat proses observasi dan kegiatan penelitian atau wawancara berlangsung, serta dokumen foto supervisi yang dimiliki oleh Jamaah Aktif, Pendiri Masjid, Pengurus Masjid.Hasil dari peneltian ini menunjukan penilaian kinerja DKM merupakan sarana untuk memperbaiki Jajaran DKM yang tidak melakukan tugasnya dengan baik dan membuat mereka mengetahui posisi dan perannya dalam menciptakan tercapainya tujuan dari pelayanan di Masjid terhadap Jamaah dan pada pelaksanaanya kegiatan pelayanan jamaah yang dilaksanakan di Dewan kemakmuran masjid , sangat dibutuhkan untuk masyarakat ataupun jamaah sekitar Masjid Al hidayah. Ada beberapa faktor yang harus menjadi perhatian dalam kegiatan pelayanan yang dilaksanakan di Masjid Al Hidayah Kata Kunci : Analisa, Kinerja, Kepuasan Jamaah,
PENGARUH KOMPENSASI TERHADAP KINERJA GURU PADA YAYASAN PENDIDIKAN WASKITO
Authors: Gandung Muhammad 
Published: May 2019

ABSTRAKTujuan penelitian untuk mengetahui kompensasi yang diberikan Yayasan Pendidikan Waskito serta untuk mengetahui kinerja guru Yayasan Pendidikan Waskito dan seberapa besar pengaruh kompenasi terhadap kinerja guru Yayasan Pendidikan Waskito. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif hal ini dimaksudkan untuk menghitung dari angket data kompensasi yang diterima guru sebagai variabel bebas (X) yang sudah diketahui dan menghitung angket data kinerja karyawan sebagai variabel tetap (Y) yang belum diketahui dari hasil angket yang disebarkan ke guru, salah satu metode yang digunakan oleh penulis adalah dengan menggunakan model-model matematika dan statistik. Dengan mentabulasi perolehan kuesioner yang kemudian menggunakan analisis korelasi product moment, Validias, Reabilitas, Determinasi dan Uji Signifikansi. Berdasarkan hasil yang diperoleh dan sudah diolah terlebih dahulu melalui perhitungan korelasi antara kompensasi terhadap kinerja karyawan diperoleh nilai rxy determinasi sebesar 0,708 dengab korelasi determinasi sebesar 50% sedangkan 50% dipengaruhi oleh faktor lain. Kemudian dari perhitungan uji keberartian Koefisien Korelasi (Uji-t) diperoleh nilai t hitung = 3,304 dan t tabel = 2,000. Ternyata t hitung > t tabel. Dengan demikian Ho ditolak, artinya terdapat hubungan yang berarti antara Kompensasi dan Kinerja Guru. Berdasarkan hasil tanggapan responden yang diperoleh dalam penelitian maka dapat diketahui bahwa kompensasi yang diberikan oleh Yayasan Pendidikan Waskito telah dilaksanakan dengan baik sehingga kinerja guru semakin membaik. Kebijakan tersebut hendaknya dipertahankan oleh perusahaan agar semangat kerja para guru tetap tinggi sehingga tujuan Yayasan Pendidikan Waskito dan keinginan para guru dapat tercapai dengan baik. Kata kunci : Kompensasi, Kinerja
PTM AND CELL CYCLE GATING MECHANISMS DEVIATED FOR PROGRESSION OF CANCER
Authors: Beeram Eswari 
Published: May 2019

Post translational modifications like phosphorylation, Glycosylation and ADP ribosylation serves as biomarkers and are mainly involved in regulation of signalling pathways, cell polarity and cell cycle progression. So, this review helps in finding the biomarkers in understanding of cancer genome and also the deviations observed in gating mechanisms. Mucin 3 is mainly involved in EMT transition and Phosphorylation is also required for effective complex formation between catenin and cadherin. Hyaluron acts as medium for the tumors cells and aids in their movement and responsible for metastatic development. Epigenetic modification like methylation is helpful for cancerous genome to develop additional mutations for survival of the genome.
Key words: Cyclin D, PTMs, Gating, Glycosylation, Phosphorylation.