bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcomes of the amphilimus-eluting polymer-free stent for chronic total occlusion treatment: a multicentre experience
Authors: Maeremans Joren , Cottens Daan , Azzalini Lorenzo , Pereira Bruno , Godino Cosmo , Carlino Mauro , Colombo Antonio , Frambach Peter , Bellini Barbara , Candilio Luciano , Briguori Carlo , Pierri Adele , Lamers Scott , Roux Lien , Duponselle Jolien , Vrolix Mathias , Dens Jo 
Published: August 2018

Aims
Late stent thrombosis and delayed vessel wall healing remain an important issue in coronary vessels treated with drug-eluting stents (DES), especially when long-vessel segments need to be covered, like in chronic total occlusions (CTO). Avoiding polymer use to avoid chronic inflammatory responses is a potential solution to reduce target vessel failure (TVF). We aimed to validate the clinical safety and efficacy at 1 year of the polymer-free Cre8 DES vs. nonpolymer-free DES for the percutaneous treatment of CTO.

Methods
Between September 2011 and August 2016, patients were prospectively enrolled in three CTO centres. The primary endpoint was major adverse cardiac and cerebrovascular events (MACCE), including cardiac death, any myocardial infarction, stent thrombosis, TVF and target vessel revascularization.

Results
A total of 102 Cre8 and 133 non-Cre8 patients were enrolled. At 1 year, a low cumulative MACCE was observed in the Cre8 group (6.9%, respectively). Moreover, a numerical trend towards better MACCE was observed in the Cre8 group vs. the non-Cre8 group (6.9 vs. 14.3%; P = 0.065). The clinically driven TVF rate was not statistically different between Cre8 and non-Cre8 patients (6.9 vs. 9.8%; P = 0.373). A borderline significant difference regarding mortality was observed in favour of Cre8 patients (0 vs. 3.8%; P = 0.049).

Conclusion
Low rates of MACCE and TVF up to 1 year were observed in the Cre8 group, supportive of the use of polymer-free DES for lesions with high complexity.
Luce Irigaray
Authors: Karcher Katharina , Karcher Katharina 
Published: August 2018

Luce Irigaray is the Director of Research in Philosophy at the Centre National de la Recherche Scientifique de Paris. A doctor in linguistics and philosophy, a leading cultural theorist, an experienced therapist and author of more than 30 books on a range of subjects, Luce Irigaray truly is an interdisciplinary thinker. Thanks to support from the French Embassy in London, the Institute of Advanced Study, the Centre for the Study of Women and Gender, the Society for Women in Philosophy (SWIP), and the Departments of English and History, she visited the University of Warwick on 7 June 2013. A lecture and roundtable discussion was attended by students and academics from many different departments, forming questions and ideas across and beyond disciplines. The day concluded with a reception and animated conversations that carried on until late in the evening. Before leaving Warwick, Luce Irigaray kindly agreed to give an exclusive interview to ‘Exchanges’, some of which is included in this discussion of her ideas.
Community-based prevalence versus hospital-based incidence of genital Human Papillomavirus infection in Central Vietnam
Authors: Nguyen Vu Quoc Huy , Ngo Viet Quynh Tram , Le Minh Tam , Nguyen Hoang Bach , Phan Van Bao Thang , Truong Quang Vinh , Cao Ngoc Thanh , Cappuccinelli Piero 
Published: August 2018

Introduction: This study aims to determine the genital HPV prevalence in reproductive-age women in Thua Thien Hue Province and comparison with HPV incidence in Hue University Hospital, Vietnam.
Methodology: Cross-sectional study on 1,034 women of reproductive age from 11 communes/wards of three districts representing three different geographic areas of Thua Thien Hue Province, Vietnam. The hospital-based group included 102 women with cervicitis and/or abnormal Pap smear result coming to Hue University Hospital. Extracting DNA from cervical samples, performing the real-time PCR for detecting HPV and the reverse dot-blot assay for HPV typing in HPV positive cases.
Results: In community, HPV prevalence was 0.9%. Mean-age of HPV positive group was 37.9 ± 6.2 years. The detected low-risk types were 6 and 11; high-risk types include 16, 18, 33, 45, 52, and 58. Single-type infection was found in 66.7% of cases. In hospital-based group, 41.2% of women have been infected with HPV, 6 different HPV types were detected. HPV18 was the most frequent high-risk type (33.3%), followed by HPV16 (15.1%); HPV6 was the most frequent among low-risk HPV types (31.2%). Single-type infection rate was 33,3%; 2 and 3 types co-infections were 28,6% and 38.1%, respectively.
Conclusions: Routine screening of high-risk HPV infection in women with symptomatic gynecologic infection and/or abnormal Pap smear appears to be benefit in early detection and prevention of cervical cancer, due to the high incidence of HPV infection.
Assessment of different storage conditions for Staphylococcus hyicus survival
Authors: Ludwig Takeuti Karine , Bernardi Mari Lourdes , Micke Moreno Andrea , Emilio Santos Neves de Barcellos David 
Published: August 2018

Introduction: Collecting swabs from skin lesions for bacteriological examination is frequently performed to the diagnosis of exudative epidermitis. This method is fast and non-invasive, but it depends directly on the viability of bacteria in clinical samples, which can be influenced by storage and shipment temperatures and the time of transportation. The aim of this study was to assess the capacity of four commercial transport media and swabs with no transport medium to preserve Staphylococcus hyicus (S. hyicus) for up to 10 days at room temperature and under refrigeration.
Methodology: Samples were stored in swabs with no transport medium and four transport media (Amies, Amies with charcoal, Cary Blair and Stuart) for 10 days at room temperature and under refrigeration. Swabs were plated in Tween 80 Agar and colonies counted.
Results: Samples kept in transport media showed better performance (P < 0.05) under refrigeration. Storage under refrigeration in Amies medium showed better results than all other transport media and swabs (P < 0.05). Amies medium and swabs with no transport medium showed comparable results in room temperature (P > 0.05). In additional, refrigerated Amies medium and swabs with no transport medium at room temperature showed high performance for up to nine and three storage days, respectively.
Conclusions: The recovery of S. hyicus in samples stored in Amies medium under refrigeration was higher when compared to other transport media. In addition, swabs with no transport medium could also be indicated when samples are stored at room temperature within three days.
Posture adjustment of workpiece based on stepwise matching by self-adaptive differential evolution algorithm
Authors: Jiang Lei , Li Yong , Zou Yisheng , Tang Kun , Fu Yulong , Ma Shuwen 
Published: August 2018

Abstract. The workpiece contour errors from previous process affect current and
subsequent process. In order to improve the uniformity of workpiece allowance
distribution, a stepwise workpiece matching adjustment method with contact
inspection is developed. This method includes two stepwise registration
processes. At first, some pairs of measured points on the theoretical and
actual surfaces are selected to build the corresponding local coordinate
systems, and then the rough matching matrixes are obtained by the coordinate
systems alignment. During the fine matching process, the objective function
based on the least square method is established by the measured point sets
adjusted through the rough matching. The fine matching matrixes can be
obtained by self-adaptive differential evolution algorithm. The posture
adjustment can be realized by transforming coordinate systems of 5 axis
machine tool, of which adjusted values can be calculated by the matching
matrixes and the machine tool topology. At last, some experiments were
presented to demonstrate the performance of the method.
Aspects d’oralité dans l’écriture romanesque d’Alain Mabanckou
Authors: Ouadiabantou Patrick Armand 
Published: August 2018

L’objectif principal de cet article est de montrer, à partir d’illustrations tirées des romans African Psycho, Verre Cassé, Mémoires de porc-épicet Black Bazard’Alain Mabanckou, que l’oralité influe profondément sur l’orthographe. Cet auteur transcrit les sons dans le tissu textuel de ses romans. À l’ère de nouvelles technologies de l’information et de la communication, mieux de l’internet, rendu performant par la structuration de la fibre optique, l’envoi des messages (sms) téléphoniques consacre un culte à la perversion orthographique dans les structures phrastiques. Cette tendance à travestir l’orthographe, de plus en plus répandue chez les auteurs francophones, présage une variété de langue française affranchie des normes rigoureuses qui, jusqu’ici, l’ont régie, comme le signale Charles Bally (1932; p. 25 ) : « Il y a une pathologie linguistique qui est une exagération du fonctionnement normal » du français. Le français moderne est-il vu comme une langue peu rigoureuse, moins surveillée donc licencieuse?
Des fous rires autour du Führer chez Timur Vermes et François Saintonge
Authors: Bergeron Patrick 
Published: August 2018

La représentation comique d’Adolf Hitler n’est pas un phénomène nouveau puisque des exemples de ridiculisation du Führer s’observent dès le début des années 1940, notamment dans des films de propagande antinazie comme The Great Dictator de Charlie Chaplin. Ce qu’il y a de plus troublant, trois quarts de siècle après la fin de la Seconde Guerre mondiale, c’est le traitement frivole et décontextualisé que suscite le tyran nazi. Pour en rendre compte, nous avons choisi d’analyser deux romans récents – Il est de retour de Timur Vermes et Dolfi et Marylin de François Saintonge – parce qu’ils permettent de réfléchir aux principaux enjeux qui émanent de cette forme particulière d’humour noir. Rire d’Hitler, ou autour de lui, ne fait pas que nous amener aux limites de l’acceptabilité sociale en matière comique; cela vient également tester notre lucidité devant les dangers que l’Histoire se répète.
Polymeric Graphene Bulk Materials with a 3D Cross‐Linked Monolithic Graphene Network
Authors: Chen Wangqiao , Xiao Peishuang , Chen Honghui , Zhang Hongtao , Zhang Qichun , Chen Yongsheng 
Published: August 2018

AbstractAlthough many great potential applications are proposed for graphene, till now none are yet realized as a stellar application. The most challenging issue for such practical applications is to figure out how to prepare graphene bulk materials while maintaining the unique two‐dimensional (2D) structure and the many excellent properties of graphene sheets. Herein, such polymeric graphene bulk materials containing three‐dimensional (3D) cross‐linked networks with graphene sheets as the building unit are reviewed. The theoretical research on various proposed structures of graphene bulk materials is summarized first. Then, the synthesis or fabrication of these graphene materials is described, which comprises mainly two approaches: chemical vapor deposition and cross‐linking using graphene oxide directly. Finally, some exotic and exciting potential applications of these graphene bulk materials are presented.
Toothed Substrate Design to Improve Stretchability of Serpentine Interconnect for Stretchable Electronics
Authors: Zhao Qian , Liang Ziwei , Lu Bingwei , Chen Ying , Ma Yinji , Feng Xue 
Published: August 2018

AbstractIntegration of deformable serpentine interconnects and inorganic functional materials with soft elastomeric substrate enables the electronics to deform into arbitrary desired shapes. Conventionally, the serpentine interconnects are bonded to a planar substrate, which limits the out‐of‐plane buckling of the serpentine interconnects, and thus restricts their stretchability. An integrated system combining serpentine interconnects with toothed substrate is proposed here to release part of the serpentine interconnects from the substrate. The advantage of this integrated system is its superior stretchability compared with the serpentine interconnects on a conventional planar substrate. Moreover, the position deviation of the serpentine interconnects to the toothed substrate influences the stretchability only in one direction, and the influence is predictable and ranges in an acceptable region. Combined analytical models and numerical simulations establish the stretchability of the integrated system, and the considerations that dictate roof collapse between the freestanding part of the serpentine interconnects and substrates. Examples of serpentine interconnects bonded on toothed and planar substrates are prepared, and low‐cycle fatigue tests are used to confirm the superior stretchability of toothed substrate by examining fatigue cracks associated with plastic deformation.
P53 protein overexpression in de novo acute myeloid leukemia patients with normal diploid karyotype correlates with FLT3 internal tandem duplication and worse relapse‐free survival
Authors: Assi Rita , Gur Hatice D. , Loghavi Sanam , Konoplev Sergej N. , Konopleva Marina , Daver Naval , Tashakori Mehrnoosh , Kadia Tapan , Routbort Mark , Salem Alireza , Kanagal‐Shamanna Rashmi , Quesada Andres , Jabbour Elias J. , Kornblau Steven M. , Medeiros L. Jeffrey , Kantarjian Hagop , Khoury Joseph D. 
Published: August 2018

AbstractAlthough ~50% of acute myeloid leukemia (AML) patients have a normal diploid karyotype by conventional cytogenetics at diagnosis, this patient subset has a variable disease course and outcome. Aberrant overexpression of the p53 protein is usually associated with TP53 alterations and a complex karyotype, but the prevalence and impact of p53 overexpression in AML with diploid cytogenetics is unknown. We examined 100 newly diagnosed AML patients to evaluate the impact of p53 expression status quantified in bone marrow core biopsy samples using immunohistochemistry and computer‐assisted image analysis. A total of 24 patients had p53 overexpression defined as 3+ staining intensity in ≥5% of cells; this finding correlated with lower platelet counts (P = .002), absence of CD34 expression in blasts (P = .009), higher bone marrow blast counts (P = .04), and a higher frequency of FLT3 internal tandem duplication (P = .007). Overexpression of p53 independently predicted for shorter leukemia‐free survival in patients who underwent allogeneic stem cell transplantation by univariate (P = .021) and multivariate analyses (P = .004). There was no correlation between MDM2 and p53 protein expression in this cohort. We conclude that p53 expression evaluated by immunohistochemistry in bone marrow biopsy specimens at the time of AML diagnosis may indicate distinct clinical characteristics in patients with normal diploid cytogenetics and is a potentially valuable tool that can enhance risk‐stratification.
Stickiness of the Hydrogen Bond
Authors: Fernández Ariel 
Published: August 2018

AbstractThe dielectric response of bulk water follows laws of continuum electrostatics, a scheme often extrapolated without justification to treat confined interfacial water, where the Debye polarization ansatz breaks down and discrete effects matter. Reconciling the discrete behavior with the continuum equations requires a conceptual leap, all the more so when assessing the electrostatic impact of exclusion of individual water molecules. This work takes up the challenge and identifies the nanoscale stickiness of a preformed water‐embedded hydrogen bond as phenomena not encompassed by continuum laws but quantitatively predictable when adopting a nanoscale theory of dielectric response holding down to molecular dimensions. Nanoscale stickiness is known to drive basic cellular events and has been measured using a molecular force probe but its physical underpinnings and computation have been lacking so far. The findings reported may impact molecular design in bio‐nanotechnology and shed light on standing challenges in biophysics, especially on the protein folding problem, where organized compaction of the protein chain following nucleating intramolecular hydrogen bonding demands explanation.
Synthesis, characterization and biological applications of some substituted pyrazoline based palladium (II) compounds
Authors: Thakor Khyati P. , Lunagariya Miral V. , Bhatt Bhupesh S. , Patel Mohan N. 
Published: August 2018

Palladium (II) complexes of the type [PdLCl2] (where L = substituted pyrazoline ligands) have been synthesized. The metal complexes (5a‐5f) have been characterized by various spectroscopic and analytical techniques like 1H‐NMR, 13C‐NMR, LC–MS, IR, Energy‐dispersive X‐ray (EDX), electronic spectroscopy, thermogravimetric analysis (TGA), elemental analysis and conductance measurement. Complexes to herring sperm DNA (HS‐DNA) binding has been explored by absorption titration and binding constant (Kb) as well as Gibb's free energy have been evaluated. Complex 5b shows the highest binding constant value. So, thermodynamic parameters of 5b‐HS DNA complex at different temperature have been evaluated. Also, Viscosity measurement and molecular modeling studies have been performed to know the binding mode of complexes. Based on the observations, an intercalative binding mode of DNA has been proposed. Further confirmation of intercalative mode of DNA binding has been taken by fluorescence spectroscopy and results are in a good agreement with absorption titration, viscosity measurement and molecular modeling data. Antibacterial activity of the complexes has been screened against pathogenic bacteria such as S. aureus, E. coli, B. subtilis, S. marcescens and P. aeruginosa. Cytotoxicity is performed on brine shrimp and S. pombe. Gel electrophoresis assay demonstrates that all the complexes can cleave the pUC19 plasmid DNA. Anti‐tuberculosis activity has been carried out using mycobacterium tuberculosis H37Rv bacteria by L.J. Medium conventional method.
Go with the Flow—Microfluidics Approaches for Amyloid Research
Authors: Zilberzwige‐Tal Shai , Gazit Ehud 
Published: August 2018

AbstractThe rapid development of cost‐efficient microfluidic devices has received tremendous attention from scientists of diverse fields. The growing potential of utilizing microfluidic platforms has further advanced the ability to integrate existing technology into microfluidic devices. Thus, allowing scientists to approach questions in fundamental fields, such as amyloid research, using new and otherwise unachievable conditions. Amyloids are associated with neurodegeneration and are in the forefront of many research efforts worldwide. The newly emerged microfluidic technology can serve as a novel research tool providing a platform for developing new methods in this field. In this review, we summarize the recent progress in amyloid research using microfluidic approaches. These approaches are driven from various fields, including physical chemistry, electrochemistry, biochemistry, and cell biology. Moreover, the new insights into novel microfluidic approaches for amyloid research reviewed here can be easily modified for other research interests.
Optimal consumption analysis for a stochastic growth model with technological shocks
Authors: Yuan Weipeng , Lai Shaoyong , Hu Hanlei 
Published: August 2018

AbstractAn optimal consumption problem of maximizing the expected discounted value of utility is discussed for an economic growth model with the random technological shocks. Applying the technique of dynamic programming principle, we derive the Hamilton‐Jacobi‐Bellman equation corresponding to the optimization problem and prove that the value function is a unique viscosity solution to the equation. Moreover, the optimal consumption policy is given in a feedback form under weak assumptions.
Zur Validierung von prognostizierten Verschattungszeiten im Umfeld städtischer Bebauung
Authors: Lung Thomas 
Published: August 2018

AbstractEs wird ein Prognosemodell zur Berechnung von Verschattungszeiten für komplexe Bebauungsstrukturen vorgestellt, das ausschließlich auf mathematisch‐physikalischen Gesetzmäßigkeiten beruht und keine Konventionswerte, Normvorgaben oder Hypothesen verwendet. Eine Überprüfung der prognostizierten Verschattungszeiten durch Beobachtungen der Schattenperioden im Umfeld von vier Berliner Hochbauten ergab gute Übereinstimmungen innerhalb der zu erwartenden Fehlermargen, die in der Hauptsache durch Koordinatenrundung der Gebäudekubatur und des Beobachterortes auf ganze Meter bedingt sind. Dabei dient das hier vorgestellte Berechnungsmodell nicht der Visualisierung von Gebäudeschatten für Verschattungsstudien, sondern der präzisen und validierten Errechnung von Verschattungszeiten an vorgegebenen Aufpunkten auf der Grundlage eines möglichst einfach und schnell zu erstellenden digitalen dreidimensionalen Gebäudemodells. Es ist sowohl für Bestandssituationen als auch für bauvorhabenbezogene Neu‐ oder Umbauten nutzbar. Das Prognosemodell ProShad wird auch dazu eingesetzt, Verschattungszeiten im Umfeld von Gebäudekomplexen als dreidimensionale Matrix zu berechnen, so dass Horizontal‐ und Vertikalschnitte durch den Schatten(stunden)raum z. B. als Bodenschattenkarten oder Fassadenverschattungen in Isoflächendarstellung von Intervallen der Verschattungsstunden eine flächendeckende Übersicht geben.
Electrochemical Performance and Ageing Mechanisms of Sol‐Gel Synthesized Na2/3[Mn3/5Fe2/5]O2 for Sodium‐Ion Batteries
Authors: Nayak Prasant K. , Yang Liangtao , Pollok Kilian , Langenhorst Falko , Wondraczek Lothar , Adelhelm Philipp 
Published: August 2018

AbstractMn and Fe based layered oxide materials are potential cost‐effective cathodes for application in Na‐ion batteries. In the present study, Na2/3[Mn3/5Fe2/5]O2 is synthesized by a sol‐gel method using citric acid as chelating agent, followed by annealing at 900 °C for 12 h. The prepared oxide material is characterized by XRD, SEM and TEM. The electrochemical performance of this cathode material is tested through galvanostatic charge‐discharge cycling in the two potential ranges of 2.0–4.2 V and 1.5–4.2 V in Na‐ion half‐cells using Na foil as the counter and reference electrodes. The material exhibits an initial capacity of about 130 mAh g−1 when cycled at 15 mA g−1 in the potential range of 2.0–4.2 V. The capacity decreases to about 105 mAh g−1 upon cycling retaining about 80 % capacity after 100 cycles. When cycled in the potential range of 1.5–4.2 V, a higher initial capacity of about 150 mAh g−1 is found, which decreases to 90 mAh g−1, thus retaining about 60 % capacity after 100 cycles. These results indicate that Na2/3[Mn3/5Fe2/5]O2 can be a potential cathode material for Na‐ion batteries, when cycled in the potential range of 2.0–4.2 V. TEM analysis of cycled materials shows the formation of secondary Mn−Fe oxide phases along with a change in the oxidation states of the transition metals. The amount of these secondary phases is larger for the sample cycled between 1.5–4.2 V, indicating their crucial role in the ageing mechanism.