bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lanthanide Coordination Polymers and MOFs based on the Dicyanodihydridoborate Anion
Authors: Zottnick Sven H. , Daul Wiebke G. , Kerpen Christoph , Finze Maik , Müller‐Buschbaum Klaus 
Published: August 2018

AbstractNew lanthanide cyanoborates were synthesized from anhydrous lanthanide chlorides and the acid H[BH2(CN)2] in either acetonitrile or pyridine. Reactions in acetonitrile lead to three‐dimensional, anionic metal‐organic frameworks (MOFs) 3∞[Ln2{BH2(CN)2}9]⋅[Ln(CH3CN)9] (Ln=Ce, Eu, Tb) which incorporate complex cations [Ln(CH3CN)9]3+ in the pores of the framework for charge compensation. In contrast, the reactions in pyridine result in the formation of one‐dimensional coordination polymers 1∞[H(py)2][LnCl2{BH2(CN)2}2(py)2]⋅0.5 py (Ln=Ce, Pr, py=pyridine) with [H(py)2]+ as counter ions for the anionic strand structure. The products show intense photoluminescence, for Ce3+ based on 5d–4f transitions in the blue spectral region, whereas the Eu3+ and Tb3+ compounds exhibit characteristic photoluminescence based on 4f–4f transitions of the respective lanthanide ions. The observed photoluminescence is mainly attributed to a direct excitation of the lanthanide ions and sensitization of the lanthanide ions by the [BH2(CN)2]− anions. These results mark the utilized borate anions as versatile building block for new coordination compounds.
Chiral separation and determination of amino acid enantiomers in fruit juice by open‐tubular nano liquid chromatography
Authors: Aydoğan Cemil 
Published: August 2018

AbstractA novel chiral porous‐layer stationary phase was developed for use in open‐tubular nano liquid chromatography. The stationary phase was prepared by an in‐situ polymerization of 3‐chloro‐2‐hydroxypropylmethacrylate (HPMA‐Cl) and ethylene dimethacrylate (EDMA). The reactive chloro groups at the surface of the porous stationary phase were reacted with β‐Cyclodextrin (β‐CD). The resulting morphology was characterized by using scanning electron microscopy (SEM) and Fourier‐transform infrared spectroscopy (FT‐IR). The chromatographic performance of the column was evaluated by hydrophilic interaction chromatography (HILIC). Amino acids were used as test solutes. The running buffer conditions for the enantioseparation were found to be 85% acetonitrile (ACN):10%MeOH: 5% H2O at 0.1% v/v trifluoro acetic acid (TFA) (flow rate: 800 nL/min). The enantioseparation provided high theoretical plate numbers up to 26 000 platesm−1. A good retention capacity within satisfactory retention times was also achieved. Real sample applicability of this column to the separation of amino acid enantiomers in fruit juice sample was demonstrated.
A fundamental equation for describing the rate of bedrock erosion by sediment‐laden fluid flows in fluvial, coastal, and aeolian environments
Authors: Sunamura Tsuguo 
Published: August 2018

AbstractA major physical process shaping bedrock landforms in fluvial, coastal, and aeolian environments is abrasion by sediment‐carrying fluid flows. A unifying formula to describe the rate of abrasion occurring in these environments has not been presented, the exploration of which is the purpose of this study. Considering the threshold concept the formulation is made including erosivity of fluid flows and erodibility of bedrock. The formula is described as dΓ/dt=C[(FA/FR) – 1], whereΓis the amount of erosion, i.e. eroded length (distance), volume, mass, or weight,tis the time, dΓ/dtis the erosion rate,FA(=Ax [fluid force]) is the assailing force of sediment‐laden fluid flows used as an index of the flow erosivity,FR(=Bx [bedrock strength]) is the resisting force representing the bedrock erodibility,Cis a coefficient with the same unit as that of dΓ/dt, andAandBare dimensionless coefficients. The equation is confirmed by existing laboratory abrasion data and its applicability is examined using existing laboratory data of fluvial and aeolian abrasion experiments and field data from a coastal area. Examinations applying fluvial and aeolian abrasion data indicate that the coefficientCis found to represent the amount of sediment working as abrasives in fluid flows and the hardness of sediment relative to bedrock; andAis presented to reflect the particle size of the sediment. The coefficientBis a conversion factor from conventional mechanical strength of rocks to the resisting force. Selecting appropriate physical quantities forFAandFRenables the application of this equation to abrasion studies on various landforms in these environments. © 2018 John Wiley & Sons, Ltd.
Synthesis of butenolides by reactions of 3‐alkenoic acids with diphenyl sulfoxide/oxalyl chloride
Authors: Ding Rui , Li Yaxi , Liu Yongguo , Sun Baoguo , Yang Shaoxiang , Tian Hongyu 
Published: August 2018

AbstractButenolides are of high interest as potential flavouring compounds. Efficient and general methods for the production of these compounds remain to be developed. A series of butenolides were prepared starting from 3‐alkenoic acids with diphenyl sulfoxide/oxalyl chloride, followed by treatment with bases. The 3‐alkenoic acids with alkyl substitutents on the double bond were converted into the corresponding 2‐butenolides with yields of greater than 77%, whereas those with aryl groups on the double bond produced the corresponding 3‐butenolides with yields of about 80%. The butenolides were produced by β eliminations of the corresponding chlorolactones, which were generated from the chlorolactonization of 3‐alkenoic acids. The chlorodiphenylsulfonium salt produced from the reaction between diphenyl sulfoxide and oxalyl chloride was supposed to be the chlorinating reagent for the chlorolactonization. This is a very simple and convenient method for the preparation of butenolides.
Commercial Interests, the Technological Imperative, and Advocates: Three Forces Driving Genomic Sequencing in Newborns
Authors: Pereira Stacey , Clayton Ellen Wright 
Published: August 2018

AbstractWhile the NSIGHT program was driven by a desire to define and gather data about both the benefits and harms of introducing genomic sequencing into the care of newborns, it remains to be seen how much influence these data will have in shaping the use of this technology in newborns. Ultimately, three additional forces—commercial interests, the technological imperative, and advocates—may play a significant role in shaping the use of sequencing in newborns. Policy‐makers and clinicians should be aware of the effects of these additional forces when considering the appropriate use of this technology in clinical practice and public health screening programs.
Epistemic layers in development planning: A case study of the health sector in the Gunungkidul District, Indonesia
Authors: Purwaningrum Farah , Short Stephanie Doris 
Published: August 2018

SummaryThe paper analyses how knowledge systems and epistemic cultures contribute to development planning through conduct of a microqualitative sociological case study of the health sector in Indonesia. The data were attained from 37 in‐depth interviews and a stakeholder engagement workshop conducted in Gunungkidul, Yogyakarta, complemented with documentary media analysis. Our findings show that centralisation continues to exist in the development planning practice within the decentralisation era. This is shown through dependence on budget prescriptions and indicators from the centre in Jakarta. Further, this study demonstrates how the integration of indicators in the development planning process is hampered by myopic practices of government officials at the district level where there is evidence of an absence of verified knowledge in the Health Bureau of the District of Gunungkidul. Furthermore, there is dependence on data and information from volunteers in the Health Integrated Service Post (Posyandu) at the local village level. This study reveals, therefore, that development planning operates at three levels, yet with different knowledge systems and epistemic cultures at each level: central, district, and village.
Stock prices' interdependence during the South Sea boom and bust
Authors: Choudhry Taufiq 
Published: August 2018

AbstractThis paper empirically investigates interdependence between major companies' stock prices during the 1720 South Sea boom and bust. This was one of the first documented major financial crashes in the European market. Empirical tests are conducted by means of rolling coefficients, multivariate cointegration, rolling cointegration, and causality tests. Results indicate a substantial interdependence among the stock prices during the boom but not during the bust period. This result implies the failure of the efficient market hypothesis and the diminishing ability of the investors to reduce portfolio risk via diversification during the boom period. The causality test results provide ample evidence of short‐term interaction between shares during the period of increasing prices.
A large posterior encephalocele associated with severe ventriculomegaly, cerebellar atrophy and transposition of the great arteries
Authors: Inan Cihan , Cenk Sayin Niyazi , Gurkan Hakan , Erzincan Selen Gursoy , Uzun Isil , Sutcu Havva , Atli Emine Ikbal , Varol Fusun 
Published: August 2018

AbstractPosterior encephalocele is a neural tube defect, which is a sac‐like protrusion of the neural tissue and cerebrospinal fluid through a defect in the occipital bone. This embryonic anomaly may coexist with cortical dysplasia, agenesis of the corpus callosum, hydrocephalus, microcephaly, craniofacial abnormalities, ventricular and atrial septal defect. We report a case of a large posterior encephalocele in a fetus accompanied by unexpected major abnormalities including transposition of the great arteries, severe ventriculomegaly and cerebellar atrophy. Postnatal surgical corrections of the posterior encephalocele and then of the transposition of the great arteries were performed but the neonate died 2 months after delivery.
Application of continuum damage mechanics model in terms of fatigue life assessment for low cycle and quasi static loadings
Authors: Skibicki D. , Ligaj B. 
Published: August 2018

AbstractThe aim of this study is to test the classical Lemaitre model based on continuum damage mechanics (CDM) approach in the range of low cycle and quasi‐static fatigue life. Study is carried out with the use of results of experimental tests for C45 steel (according to AISI: 1045 steel) carried out under variable‐amplitude loading. Loading programs are of two‐step character and include blocks of cycles of different lengths and R =  ‐1 coefficients. Fatigue lives are calculated according to Lemaitre model from experimentally obtained stress and strain histories recorded during fatigue tests. The results are compared with experimental tests results and with fatigue lives calculated with the use of by traditional fatigue approach based on Palmgren‐Miner damage summation hypothesis. Experimental test of fatigue life calculation results for C45 steel reveals that continuum damage method, using the recorded stresses and strains, predicts fatigue life better as compared to the remaining methods. The study also contains many detailed analyses of experimental results.
Untersuchungen zum Elektronenstrahl‐Randschichtumschmelzen einer sprühkompaktierten übereutektischen eisenhaltigen Al‐Si‐Legierung
Authors: Hegelmann E. , Jung A. , Hengst P. , Buchwalder A. , Zenker R. 
Published: August 2018

AbstractIm vorliegenden Beitrag wird der Einfluss verschiedener Strahlführungstechniken auf das Behandlungsergebnis des Elektronenstrahl‐Randschichtumschmelzens einer sprühkompaktierten übereutektischen Aluminiumlegierung (AlSi17Fe5Cu4Mg) untersucht. Durch Nutzung der verfahrensspezifischen hohen Erwärm‐ und Abkühlraten beim Elektronenstrahlumschmelzen einerseits und dem hohen Legierungsgehalt des Werkstoffs andererseits, konnte das Randschichtgefüge so modifiziert werden, dass eine ca. 3‐fach höhere Härte (284 HV 0,1) im Vergleich zum Grundwerkstoff eingestellt wurde (104 HV 0,1). Das liegt deutlich über dem Niveau einer konventionellen Wärmebehandlung (ca. 170 HV 0,1). Als härtesteigernde Mechanismen konnten dabei neben der Phasenneubildung, die Kornfeinung und die Übersättigung des Aluminiummischkristalls ermittelt werden. Es wird dargelegt, welche Einflüsse die Strahlführung sowohl auf die Oberflächendeformation als auch die Gefügebildung hat. Letzteres beeinflusst im entscheidendem Maße das Verschleißverhalten unter abrasiven (Ritztest) sowie abrasiv‐adhäsiven (Stift‐Scheibe) Beanspruchungsbedingungen. Umschmelzschichten, die mittels einer Mäandertechnik erzeugt wurden, zeigten eine deutliche Verbesserung hinsichtlich des Verschleißverhaltens.
Common holdings and strategic manager compensation: The case of an asymmetric triopoly
Authors: Neus Werner , Stadler Manfred 
Published: August 2018

AbstractWe study an asymmetric triopoly in a heterogeneous product market where quantity decisions are delegated to managers. The two biggest firms are commonly owned by shareholders such as index funds, whereas the smallest firm is owned by independent shareholders. Under such a common holding owner structure, the owners have an incentive to coordinate when designing their manager compensation schemes. This coordination leads to a reallocation of production and induces a redistribution of profits. The trade volume in the market is reduced so that shareholder coordination is detrimental to consumer surplus as well as welfare.
Children with HbSβ0 thalassemia have higher hemoglobin levels and lower incidence rate of acute chest syndrome compared to children with HbSS
Authors: Day Melissa E. , Rodeghier Mark , DeBaun Michael R. 
Published: August 2018

AbstractBackgroundBased on the presumed clinical similarity between the two most severe sickle cell disease (SCD) genotypes, hemoglobin (Hb) Sβ0 thalassemia and HbSS, randomized controlled trials (RCTs) have included both genotypes. Our group has demonstrated that healthcare providers inadequately distinguish the two diagnoses through clinical and laboratory parameters.ProcedureIn a retrospective cohort study utilizing data from the Silent Cerebral Infarct Transfusion trial (NCT00072761), we tested the hypothesis that children with genotypic diagnoses of HbSβ0 thalassemia, when compared to HbSS, have significantly different rates of SCD comorbidities. Exclusion criteria included those with previous overt stroke or treatment with hydroxyurea or regular blood transfusion therapy.ResultsAmong children with HbSβ0 thalassemia (n = 22) and HbSS (n = 786), the mean hemoglobin was higher in children with HbSβ0 thalassemia (9.2 g/dl) compared to HbSS (8.1 g/dl, P < 0.001). In children with HbSβ0 thalassemia, when compared to HbSS, the incidence rate of acute chest syndrome (ACS) was 3.0 and 14.4 events per 100 patient‐years (P = 0.028), and mean transcranial Doppler (TCD) velocities were 112.6 and 135.6 cm/sec, respectively (P = 0.026). The number of children with HbSβ0 thalassemia and HbSS with conditional TCD velocities were zero (0%) and 26 (4.9%), respectively (P = 1.00), and the number with silent cerebral infarcts were five (27.8%) and 209 (30.8%), respectively (P = 0.78).ConclusionsWe have provided preliminary evidence that clinically relevant differences occur in ACS rates and TCD velocities between children with HbSβ0 thalassemia and HbSS. Future SCD RCTs should consider balanced allocation of these SCD genotypes, particularly when ACS and abnormal TCD velocities are primary outcome measures.
Acquired ornithine transcarbamylase deficiency in pediatric and adolescent patients with fibrolamellar hepatocellular carcinoma
Authors: Bartlett Allison L. , Leslie Nancy D. , Gupta Anita , Geller James I. 
Published: August 2018

AbstractOrnithine transcarbamylase deficiency (OTCD) disrupts the metabolic pathway responsible for converting nitrogenous waste to urea, allowing for excretion. When impaired, ammonia levels accumulate in the blood resulting in severe, sometimes life‐threatening toxicities. Abnormalities of the urea cycle are often inherited, though there are some rarer acquired forms. We describe two cases of acquired OTCD in pediatric patients with fibrolamellar hepatocellular carcinoma (FL‐HCC). We detail its presentation and management, explore potential underlying pathophysiology, and propose a practice change to optimize care of FL‐HCC patients.
Chromosomal microarray analysis on uncultured chorionic villus sampling can be complicated by confined placental mosaicism for aneuploidy and microdeletions
Authors: Gu Shen , Jernegan Madison , Van den Veyver Ignatia B. , Peacock Sandra , Smith Janice , Breman Amy 
Published: August 2018

AbstractObjectiveThis study aims to establish the incidence and implications of confined placental mosaicism (CPM) in the context of prenatal chromosomal microarray analysis (CMA).MethodsWe retrospectively reviewed prenatal array data on 1382 consecutive chorionic villus sampling (CVS) specimens spanning the past 6 years, focusing on those for which whole CVS biopsy (both cytotrophoblast and mesenchymal cells) was used for CMA and cultured cells (primarily mesenchyme) was also analyzed or amniotic fluid (AF)/newborn blood was used for confirmation, to determine the frequency of mosaic abnormal findings that were the result of CPM.ResultsOut of a total of 1382 consecutive CVS cases, we identified 42 (42/1382 = 3.0%) cases with abnormal array findings suggestive of mosaicism. Among them, 10 cases were unequivocally interpreted as CPM based on a normal AF/newborn blood confirmatory result. In addition, another 10 cases were interpreted as provisional CPM based on normal results on cultured cells. Notably, 40% (8/20) of the cases revealed complex findings, including multiple mosaic aneuploidies, mosaic submicroscopic copy number variation (CNV), and mosaic aneuploidy plus mosaic CNV.ConclusionAbnormal CMA results from CVS specimens should be interpreted with caution when mosaicism is evident or suspected. Furthermore, confirmatory testing on amniotic fluid, which contains cells derived from the fetus, is recommended in these cases.
Degradable alternating polyperoxides from poly(ethylene glycol)‐substituted styrenic monomers with water solubility and thermoresponsiveness
Authors: Mete Sourav , Choudhury Neha , De Priyadarsi 
Published: August 2018

ABSTRACTWater soluble alternating copolymers were prepared by oxidative free radical copolymerization of 4‐vinylbenzyl methoxypoly(oxyethylene) ether (PEGSt) and molecular oxygen at 50 °C. NMR spectroscopy established alternate sequence of PEGSt and peroxy bonds (OO) along the polymer main‐chain. The obtained polymers show temperature induced hydrophilic to hydrophobic phase separation, confirmed by UV‐visible spectroscopy and dynamic light scattering. The cloud point temperature (TCP) of the polymers can be tuned by changing the chain length of side‐chain poly(ethylene oxide) and incorporation of hydrophobic methyl methacrylate in the copolyperoxides. Exothermic degradation of these polyperoxides was confirmed by differential scanning calorimetry and the degradation products have been characterized by electron impact mass spectroscopy. Finally, N,N‐dimethylacrylamide was polymerized in the presence of these polyperoxides in toluene, highlighting their potential as polymeric free radical initiator during polymerization of vinyl monomers. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 2030–2038
Characterization of the two conformations adopted by the T3SS inner‐membrane protein PrgK
Authors: Bergeron Julien R. C. , Brockerman Jacob A. , Vuckovic Marija , Deng Wanyin , Okon Mark , Finlay B. Brett , McIntosh Lawrence P. , Strynadka Natalie C. J. 
Published: August 2018

AbstractThe pathogenic bacterium Salmonella enterica serovar Typhimurium utilizes two type III secretion systems (T3SS) to inject effector proteins into target cells upon infection. The T3SS secretion apparatus (the injectisome) is a large macromolecular assembly composed of over twenty proteins, many in highly oligomeric states. A sub‐structure of the injectisome, termed the basal body, spans both membranes and the periplasmic space of the bacterium. It is primarily composed of three integral membranes proteins, InvG, PrgH, and PrgK, that form ring structures through which components are secreted. In particular, PrgK possesses a periplasmic region consisting of two globular domains joined by a linker polypeptide. We showed previously that in isolation, this region adopts two distinct conformations, of with only one is observed in the assembled basal body complex. Here, using NMR spectroscopy, we further characterize these two conformations. In particular, we demonstrate that the interaction of the linker region with the first globular domain, as found in the intact basal body, is dependent upon the cis conformation of the Leu77‐Pro78 peptide. Furthermore, this interaction is pH‐dependent due to coupling with hydrogen bond formation between Tyr75 and His42 in its neutral Nδ1H tautomeric form. This pH‐dependent interaction may play a role in the regulation of the secretion apparatus disassembly in the context of bacterial infection.
Liposome encapsulation and EDTA formulation of dsRNA targeting essential genes increase oral RNAi‐caused mortality in the Neotropical stink bug Euschistus heros
Authors: Castellanos Nathaly L , Smagghe Guy , Sharma Rohit , Oliveira Eugênio E , Christiaens Olivier 
Published: August 2018

AbstractBACKGROUNDThe Neotropical stink bug Euschistus heros is a major pest in soybean fields. Development of highly species‐specific pesticides based on RNA interference (RNAi) could provide a new sustainable and environmentally friendly control strategy.RESULTSHere, the potential of RNAi as a pest control tool against E. heros was assessed. First, target gene selection using a microinjection approach was performed. Seven of the 15 candidate genes tested exhibited > 95% mortality after hemolymph injection of 27.5 ng dsRNA. Subsequently, dsRNA was administered orally using different formulations: naked dsRNA, liposome‐encapsulated‐dsRNA and dsRNA formulated with EDTA. Liposome‐encapsulated dsRNA targeting vATPase A and muscle actin led to significant mortality after 14 days (45% and 42%, respectively), whereas EDTA‐formulated dsRNA did so for only one of the target genes. Ex vivo analysis of the dsRNA stability in collected saliva indicated a strong dsRNA‐degrading capacity by E. heros saliva, which could explain the need for dsRNA formulations.CONCLUSIONThe results demonstrate that continuous ingestion of dsRNA with EDTA or liposome‐encapsulated dsRNA can prevent dsRNA from being degraded enzymatically and suggest great potential for using these formulations in dsRNA delivery to use RNAi as a functional genomics tool or for pest management of stink bugs. © 2018 Society of Chemical Industry
Resilient control for wireless networked control systems under DoS attack via a hierarchical game
Authors: Yuan Huanhuan , Xia Yuanqing , Yang Hongjiu , Yuan Yuan 
Published: August 2018

SummaryIn this paper, the resilient control problem is investigated for a wireless networked control system (WNCS) under denial‐of‐service (DoS) attack via a hierarchical game approach. In the presence of a wireless network, a DoS attacker leads to extra packet dropout in the cyber layer of WNCS by launching interference power. A zero‐sum Markov game is exploited to model the interaction between the transmitter and the DoS attacker under dynamic network environment. Additionally, with the attack‐induced packet loss, an H∞ minimax controller is designed in the physical layer by using a delta operator approach. Both value iteration and Q‐learning methods are used to solve the hierarchical game problem for the WNCS. The proposed method is applied to a load frequency control system to illustrate the effectiveness.