bluuebunny/crossref_metadata_2025_split huggingface dataset:
ISO 9001 Certification and Organizational Performance Among Manufacturing Companies: A Systematic Literature Review and Research Agenda
Authors: Ayyadi Ismail , Oulhadj Badia 
Published: November 2024

ABSTRACTIndustrial enterprises are pivotal in the socio‐economic landscape, yet navigating the economic and non‐economic facets of modern organizational performance presents a considerable challenge. This article embarks on a systematic literature review to probe the question: Does ISO 9001 certification play a role in mitigating the complexities of organizational performance in industrial enterprises? To address this objective, we adopted the systematic literature review protocol delineated by Petticrew and Roberts (2006). A comprehensive analysis encompassed 94 primary studies spanning 60 contexts, conducted over the period from 2000 to 2023. The findings indicate that the efficacy of ISO 9001 certification is contingent upon the extent of its direct and indirect influence on the various dimensions of organizational performance. Furthermore, the motivations for embracing this international standard, coupled with the organizational perception of the QMS, are pivotal factors. Based on these insights, we have proposed a theoretical model and formulated recommendations aimed at refining the scope and impact of future research endeavors.
Will more multinational corporations inflow approach closer toward carbon neutrality? Novel propensity score matching‐difference‐in‐difference evidence across 35 developing countries
Authors: Ali Sajjad , Ghimire Amogh , Long Xingle , Chen Lili 
Published: November 2024

AbstractThis paper mainly investigates the roles of multinational corporations (MNCs) inflow on carbon neutrality across 35 developing countries. First, we testify the role of MNCs inflow on carbon neutrality. Next, we compare the heterogenous effects of the Kyoto Protocol and the Paris Agreement on CO2 emissions. Third, this study employs the propensity score matching (PSM) difference‐in‐difference (DID) with relatively higher internal validity to evaluate the policy shock impacts of the Kyoto Protocol and Paris Agreement. Furthermore, we also explore the impact of trade competitiveness on CO2 emissions to verify the structure, technique, and scale effects of international trade. Finally, we also analyze how human capital impacts CO2 emissions from the perspective of endogenous growth, departing from exogenous growth. The findings indicate that MNCs inflow has mixed effect on CO2 emissions, due to pollution haven and halo effect. Kyoto Protocol increased CO2 emissions, whereas Paris Agreement decreased CO2 emissions. Human capital decreased CO2 emissions according to the DID model, suggesting its crucial role in achieving carbon neutrality through endogenous growth mechanisms. Renewable energy consumption reduced CO2 emissions, highlighting the importance of sustainable energy practices. Urbanization decreased more CO2 emissions in the model of Paris Agreement over that of Kyoto Protocol. Trade competitiveness exhibits mixed effects on CO2 emissions. It is better to facilitate the cleaner MNCs inflow across developing countries, aiming to decrease cross‐border pollution.
Lichen and Its Microbiome as an Untapped Source of Anti‐Biofilm Compounds
Authors: Millot Marion , Imbert Christine , Pouget Christelle , Girardot Marion , Mambu Lengo 
Published: November 2024

ABSTRACTLichen substances have been first described in the 1870s, and around 10 000 compounds have been isolated and characterized. Most of them have been evaluated for their activity on planktonic microorganisms (bacteria and fungi). More recently, microorganisms colonizing the lichen thallus have been isolated and identified using DNA sequencing, giving access to a wide diversity of culturable microorganisms. The increasing research in lichen‐associated microbiomes in recent years has emphasized a wide range of metabolites as a potential source of bioactive compounds. In parallel, humans are facing microbial resistance to conventional antimicrobial drugs. One of the reasons is the biofilm lifestyle of microorganisms. Indeed, the aggregation of microbial communities inside biofilms is now well known and characterized, and some possible ways to fight and destroy biofilms are identified (quorum sensing inhibitors, etc.). The present review aims to summarize the anti‐biofilm potential of lichen metabolites and those from their associated microorganisms (bacteria and/or fungi). Are the metabolites isolated from lichens and their associated fungi displaying any anti‐biofilm activity? This literature synthesis highlights the metabolites of interest as new anti‐biofilm drugs and shows the lack of current biological research dealing with biofilm and lichen metabolites. Acetone and ethyl acetate extracts are the most studied sources of anti‐biofilm agents. Only two lichen metabolites, usnic acid and evernic acid, have been evaluated both as antifungal and antibacterial biofilm compounds. Terpenoids from lichens are still poorly explored for this activity.
Comparative Phytochemical and Biological Studies on Salvia hispanica L., Sesamum indicum L., and Linum usitatissimum L.: A Focus on the Effect of Their Fixed Oil on the Peritoneal Fat
Authors: Abdel Raoof Gehan F. , Mahmoud Mourad Rasha M. , Mohamed Nagy Hala M. 
Published: November 2024

ABSTRACTThe current research was undertaken to investigate the effect of fixed oils of Linum usitatissimum L. (flaxseed), Sesamum indicum L. (sesame), and Salvia hispanica L. (chia) seeds on the chemical profile and weight of the peritoneal fat of rats fed normal (10% fat) or high‐fat diet (HFD) (20% fat). Additionally, to analyze the phytoconstituents of these fixed oils, gas chromatography–mass spectrometry (GC/MS) was applied to analyze the experimental oils and the peritoneal fats. Our results revealed a remarkable effect of the experimental oils on the fatty acid profile of peritoneal fat in groups fed on HFD; they limited the increase in saturated fatty acids. Moreover, adding these oils to HFD limited the increase in body weight and decreased the percentage of peritoneal fat. In addition, oleic acid was the major fatty acid in sesame and flaxseed oils (44.2% and 33.69%, respectively). However, linolenic acid was represented as a major fatty acid in chia oil (50.69%). So, we can conclude that sesame, flaxseed, and chia oils can be used as a healthy oil source in food due to their nutritional benefits and remarkable role in controlling the adverse effect of HFD on the quantity and quality of peritoneal fat.
Assessment of Bioactivity of Homalomena aromatica Essential Oil From Northeast India Through Combinative In Vitro and In Silico Approaches
Authors: Gupta Tanmita , Jayaprakash Prajisha , Tamang Raghu , Sarma Neelav , Begum Twahira , Lal Mohan 
Published: November 2024

ABSTRACTHomalomena aromatica Schott is a valuable medicinal aromatic plant having wide range of applications in ethnobotany, pharmacology, perfumery and flavor industry. Traditionally, various part of H. aromatica such as leaves and rhizomes were applied to treat joint pain, skin diseases, colds, asthma, diarrhea, and jaundice. Whole herbs extracts are used to address muscle weakness, rheumatism, and allergies, purify the blood, treat deafness, and promote wound healing, especially in postpartum women. The present study is subjected to assess anti‐inflammatory, anti‐diabetic, tyrosinase inhibitory, acetylcholinesterase (AChE), antimicrobial, and genotoxic efficacies of H. aromatica rhizome essential oil (HAEO). To validate the findings of biological assays, in silico methods including Prediction of Activity Spectra for Substances (PASS) tool, target prediction, and molecular docking were employed. Using Clevenger apparatus dry rhizome of HAEO was extracted. The chemical profiling was performed using gas chromatography/mass spectrometry (GC/MS) where HAEO yield was 1.09% ± 0.641% (v/w) with 12 compounds where linalool was identified as major compound (76.29%). Anti‐inflammatory activity showed IC50 value for protease inhibitory assay 19.59 µL/mL and albumin denaturation assay 32.16 µL/mL. The IC50 value for α‐amylase inhibitory activity showed 29.84 µL/mL, whereas tyrosinase inhibitory activity showed 73.62 µL/mL. Acetylcholinesterase inhibitory (AChEase) activity revealed an IC50 value of 38.13 µL/mL. Antimicrobial activity showed minimal inhibitory concentration (MIC) values of 10 ± 0.47 and 45 ± 0.47 µg/mL against Staphylococcus aureus and Candida albicans. Genotoxicity analysis showed HAEO has moderate toxic effect. In silico results identified six potential targets via Swiss target prediction: (AChE, CYP51, peroxisome proliferator‐activated receptor [PPAR], cyclooxygenase‐2 [COX‐2], and tyrosinase‐related protein 1 [TYRP1]). Additionally, molecular docking studies revealed Linalool −7.4 kcal/mol, Spathulenol −8.5 kcal/mol, aromadendrene oxide‐(2) −8.3 kcal/mol better docking scores. For the first time, this study reports on anti‐diabetic, anti‐tyrosinase, acetylcholinesterase inhibitory activities and genotoxicity of HAEO. In silico investigation supports these activities by evaluating binding affinities and interactions between compounds and their respective targets through molecular docking. From the current reports, HAEO can be used for development of natural drugs in near future.
Prospects of Corn (Zea mays L.) Polysaccharides: Structural Features, Bioactivities, and Applications
Authors: Xu Yi , Wang Yonghua , Wang Xiaoyue , Xu Yuyu , Tian Yang , Wang Ming 
Published: November 2024

ABSTRACTOver the past few years, the identification and study of bioactive and health‐promoting new ingredients from natural sources have garnered significant interest. Corn has increasingly come into focus due to its substantial nutritional and medicinal benefits. Research studies have shown that corn polysaccharide exhibits antitumor, antioxidative, hepatoprotective, renoprotective, hypoglycemic, immunomodulatory, and various other beneficial effects. Furthermore, variations in extraction materials and methods can result in differences in the structural and biological properties of corn polysaccharides. This article reviews the latest advancements in the extraction and purification techniques, structural characteristics, biological activities, structural modifications, and toxicological assessments of corn polysaccharides. The aim is to furnish evidence that supports the further development of corn polysaccharides as therapeutic agents and functional food ingredients.
Respiratory Failure Following a Venomous Snakebite: Importance of Ambu Bag Ventilation in a Poor‐Resource Setting
Authors: Matin Abdul , Sobuj Sarwar Alam , Saha Prity , Sami Chowdhury Adnan 
Published: November 2024

ABSTRACTVenomous snakebites are critical medical emergency. Most fatalities resulted from respiratory failure attributable to abrupt neuromuscular paralysis. A 35‐year‐old male was treated for a snakebite on the dorsum of his right foot, which occurred seven hours prior to hospital admission during sleep. The patient exhibited symptoms of headache, myalgia, extremity weakness, and altered consciousness. No hemorrhagic or myotoxic symptoms were observed. He subsequently had respiratory failure, necessitating emergency bedside intubation with an Ambu bag, followed by treatment initiated in the district hospital and continued in the intensive care unit of a medical college hospital. Timely diagnosis, immediate transport to a medical facility, and rapid bedside intubation can save the lives of individuals experiencing respiratory failure due to venomous snake bites.
Design Concepts of High‐Entropy Materials for Zinc Ion Batteries
Authors: Sun Kaisheng , Li Jiaru , Li Liang , Chao Danming 
Published: November 2024

AbstractZinc‐ion batteries have emerged as strong candidates for replacing Li/Na‐ion batteries owing to their high safety and environmental friendliness. However, the large electrostatic repulsion between the cathode and Zn2+, the irreversible growth of zinc dendrites at the anode, and the hydrogen precipitation side reaction in the aqueous electrolyte have hindered the practical application of zinc ion batteries. Fortunately, the emergence of the revolutionary concept of high entropy has provided new opportunities for the development of battery materials. High‐entropy materials, with their unique atomic structures and uniform distribution of multiple elements, offer flexible options for material compositions and electronic structures, thus attracting significant attention in battery systems. In this concept article, we summarize the definitions and intrinsic structural characteristics of high‐entropy materials and provide a detailed overview of the latest design concepts from the perspectives of cathodes, anodes, and electrolytes. Finally, we outline the challenges faced by high‐entropy materials and potential solutions to guide researchers in developing efficient and stable zinc‐ion batteries.
Free‐Standing Nanocomposite Au@Graphene Oxide Continuous Flow Synthesis in Water for Degradation of Organic Dyes
Authors: Alotaibi Badriah M. , Chen Xianjue , Alharbi Thaar M. D. , Heydari Amir , Raston Colin L. 
Published: November 2024

AbstractWe have developed a rapid and facile method for preparing free‐standing nanocomposite of gold nanoparticles with graphene oxide (Au@GO) in water under continuous flow in the absence of harsh reducing agents and any other auxiliary substances, as a method with favourable green chemistry metrics. This uses a vortex fluidic device (VFD) where induced mechanical energy and photo‐contact electrification associated with the dynamic thin film in the rapidly rotating tube tilted at 45° while simultaneously UV irradiated (λ=254 nm, 20 W) results in decomposition of water to hydrogen and hydrogen peroxide with growth of the gold nanoparticles on the surface of the GO. We have established that the resulting Au@GO composite sheets rapidly catalyse the degradation of commercial dyes like methyl orange (MO) and methylene blue (MB) using the hydrogen peroxide generated in situ in the VFD. This process relies on active radicals generated through liquid‐solid photo‐contact electrification of water in the VFD which dramatically minimises the generation of waste in industrial applications, with the reaction having implications for wastewater treatment.
Supramolecular Chiral Assembly of Dendritic Amphiphiles in Aqueous Media
Authors: Yan Jiatao , Ren Liangxuan , Lu Xueting , Li Wen , Zhang Afang 
Published: November 2024

AbstractDendritic amphiphiles are a promising class of topological blocks for self‐assembly to construct chiral supramolecular aggregates in aqueous media. Their unique dendritic geometry, structure variability and multivalence can mediate the assemblies with versatile morphologies and functions. The bulky dendritic moieties also enable the appropriate association‐repulsion balance to control supramolecular growth, and simultaneously shield the assemblies with enhanced stabilities. Moreover, the crowded packing of dendritic segments facilitates the efficient chirality transfer from molecular level to supramolecular level, to achieve chirality amplification or enhancement. Dendritic moieties also provide chances to stabilize the assemblies in aqueous media through shielding and cooperative effects. The dendritic assemblies can be intriguingly made responsive to external stimuli including temperature, light, solvents or guests to switch their nanostructures or supramolecular chirality. Various dendritic amphiphiles bearing peptide or aromatic motifs have been reported in supramolecular chiral assembly, and their functional applications investigated. This review summarizes the significant progresses with a particular focus on the dendritic structural effects on supramolecular chiral assembly and the stimuli‐responsiveness in aqueous media.
A Photolockable Polyaromatic Capsule Designed via Regiochemical Substitution
Authors: Catti Lorenzo , Yasugami Shiina , Aoyama Shinji , Kishida Natsuki , Yoshizawa Michito 
Published: November 2024

AbstractPhotocontrol over host frameworks is an elegant way to manipulate host‐guest composites, yet the majority of previous systems suffer from long irradiation time and narrow guest scope, and are restricted to intramolecular photoreactions in organic solvents. Herein we present a photolockable polyaromatic capsule with high guest binding abilities in water. The capsule assembles from bent amphiphiles featuring two 2‐subsutituted anthracene panels, which shows high stability against dilution and undergoes intermolecular [4+4] photo‐oligomerization upon short light irradiation (<10 min). The photolocked capsule provides a roughly spherical framework, with an average, core diameter of ~3 nm, composed of amphiphilic oligomers (e. g., trimer). The new capsule shows improved host ability (up to 10‐fold) in water toward various hydrophobic compounds (e. g., organic and metal‐complex dyes), as compared with an analogous, non‐photolockable capsule with 9‐subsutituted anthracene panels. In addition, the resultant dye‐loaded capsules are also successfully photolocked via short irradiation with high retention of the bound dyes.
Isolation of a Staudinger‐type Intermediate Utilizing a Five‐Membered Phosphorus‐Centered Biradicaloid
Authors: Pilopp Y. , Bresien J. , Lüdtke K. P. , Schulz A. 
Published: November 2024

AbstractThe Staudinger reaction provides chemists with a valuable tool for the reduction of azides, which are notoriously unstable and can decompose explosively. By providing a controlled method for the conversion of azides to amines, the reaction opened up new avenues for the synthesis of various amine‐containing compounds that are widely used in natural products, pharmaceuticals and polymers. The Staudinger reaction begins with the nucleophilic attack of a trivalent phosphine (usually triphenylphosphine), leading to the formation of a triazenide intermediate, a highly reactive species. Here we report how a divalent phosphorus‐centered biradicaloid reacts with covalent azides and show that it is possible to capture and fully characterize the transient intermediate. The experimental data is supported by quantum chemical calculations of the reaction paths and in terms of thermodynamics and chemical bonding.
Imaging Dihydrogen Bond‐Driven Assembly of Borazine on Au(111)
Authors: Zeilerbauer Matthias , Thaler Marco , Obwaller Barbara , Ončák Milan , Patera Laerte L. 
Published: November 2024

AbstractDihydrogen bonding (DHB) is a peculiar type of attractive interaction occurring between a partially positively charged hydrogen atom and a partially negatively charged hydrogen atom. Borazine represents a prototypical molecule exhibiting dihydrogen bonding in both gas phase, as well as in its crystalline form. For borazine assemblies on solid surfaces, a direct observation and characterization of dihydrogen bonding has remained elusive, possibly due to an intricate interplay of substrate‐molecule and intermolecular interactions. Here we present evidence of dihydrogen bonding occurring in borazine assemblies on a Au(111) surface. By means of low‐temperature scanning tunneling microscopy, we unveiled distinct configurations, exhibiting single and double dihydrogen bonding. Density functional theory calculations elucidate the interplay between substrate adsorption and intermolecular interactions to stabilize the formation of borazine dimers on Au(111). The dimers constitute the building blocks for the formation of larger assemblies.
Beyond Tuskegee: A contemporary qualitative assessment of barriers to research participation among Black women
Authors: Bontemps‐Jones Jeuneviette E. , McCullough Lauren E. , Kirkland Elizabeth G. , Teras Lauren R. , Briggs Peter , Whitt‐Glover Melicia C. , Arline‐Bradley Shavon , Winn Jamal , Lett Jason , Patel Alpa V. 
Published: November 2024

AbstractBackgroundHealth care inequities have partially contributed to the existing racial gaps in health. Despite having lower incidence rates of breast cancer, Black women have a 41% higher mortality rate than White women. Black individuals remain underrepresented in research. Diversity in research is paramount to the improvement of clinical care practices and subgroup‐specific guidelines.MethodsBlack women from various community venues across geographic regions of the United States were invited via email, online fliers, social media platforms, and word of mouth to participate in focus groups. Six online focus groups of six to 10 Black women aged 25–65 years (N = 38) with and without a history of cancer were conducted with an in‐depth semistructured discussion guide.ResultsMost participants were college educated (32 of 38; 84.2%), aged 50 years or older (31 of 38; 81.6%), and had an annual income of $50,000 or more (26 of 38; 68.4%). Several barriers to research participation were identified. They included a lack of empathy and respect in health care settings, apprehension regarding the sharing of personal information, mistrust of medical research, and logistical/technical barriers. Alternatively, building individual and community trust and communicating the value of conducting research beneficial to the Black community were viewed as facilitators to research participation.ConclusionsSuccessful engagement of Black women in research requires the acknowledgment and consideration of the numerous barriers that affect their ability to participate. Black women are more inclined to participate in research when the research team is knowledgeable, has experience within their communities, and engages trusted community partners. Additionally, the research must be meaningful and impactful to future generations of Black women.
Development of a Master Equation‐Based Microkinetic Model to Investigate Gas Phase Cluster Reactions Across a Wide Pressure and Temperature Range
Authors: Szalay Máté , Höltzl Tibor 
Published: November 2024

AbstractSmall gas‐phase metal clusters serve as model systems for complex catalytic reactions, enabling the exploration of the impacts of the size, doping, charge state and other factors under clean conditions. Although the mechanisms of reactions involving metal clusters are known in many cases, they are not always sufficient to interpret the experimental results, as those can be strongly influenced by the chemical kinetics under specific conditions. Therefore, our objective here is to develop a model that utilizes quantum chemical computations to comprehend and predict the precise kinetics of gas‐phase cluster reactions, particularly under low‐pressure conditions. In this study, we demonstrate that master equation simulations, utilizing reaction paths computed through quantum chemistry, can effectively elucidate the findings of previous experiments. Furthermore, these simulations can accurately predict the kinetics spanning from low‐pressure conditions (typically observed in gas‐phase cluster experiments) to atmospheric or higher pressures (typical for catalytic experiments). The models are tested for simple elementary steps (Cu4+H2). We highlight the importance of the reaction mechanism simplification in Cu4++H2 and provide an interpretation for the previously observed product branching in Pt++CH4.