bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relevance of Trace Elements and Oxidative Stress in Chronic Obstructive Pulmonary Disease
Authors: Das Sonu , Varghese Jinsu , Adiody Supriya , John Mathew 
Published: November 2024

ABSTRACT

Background and Aims:
Chronic Obstructive Pulmonary Disease (COPD) is a progressive and nonreversible lung disease caused by long-term exposure to harmful particles and gases, especially cigarette smoke. Emerging evidence suggests that trace minerals, including iron, copper, zinc, and the heavy metal cadmium, may also contribute to the pathogenesis and progression of this complex disease. The study was done in a tertiary care hospital in Kerala and assessed the role of trace elements and oxidative stress in the pathophysiology of COPD.

Materials and Methods:
The study comprised two groups, consisting of 30 healthy controls and 30 COPD samples. Plasma samples collected from the participants were used for the analysis of oxidative stress parameters such as lipid peroxidation, superoxide dismutase (SOD) activity, catalase activity, and glutathione concentration. The oxidative stress index (OSI) was calculated from the total oxidant status (TOS)/total antioxidant status (TAS) ratio. Plasma levels of iron, copper, zinc, and cadmium were analyzed and correlated with OSI to determine the interplay of environmental exposure to toxicants and their role in inducing oxidative stress.

Results:
The results showed an increase in plasma iron and copper levels in COPD with respect to healthy control, whereas cadmium showed an increasing trend. The OSI values obtained from the TOS/TAS ratio were higher in COPD with respect to control and showed a positive correlation to plasma levels of copper and cadmium. Pro-oxidant TBARS concentration was higher with a concurrent decrease in antioxidant enzymes SOD and catalase activity in COPD with respect to healthy controls.

Conclusion:
The study, carried out in a tertiary care hospital in Kerala, shed light on the role of plasma trace element/heavy metal imbalance in inducing oxidative stress in COPD. A significant increase in plasma iron levels may activate Fenton chemistry, thereby inducing oxidative stress, playing a major role in COPD pathophysiology. Copper and cadmium levels also positively correlated with OSI in COPD, indicating that trace elements in higher levels can lead to disease progression in COPD pathophysiology.
An Assessment of Level of Reflective Thinking among Phase I and Phase II Medical Students—A Cross-sectional Descriptive Study
Authors: Umesh B Veena , Basavarajegowda Abhishekh , Nalini YC 
Published: November 2024

ABSTRACT

Introduction:
As part of a competency-based curriculum, reflective writing (RW) is advocated right from the first MBBS, where students are expected to write reflections on the foundation course, early clinical exposure (ECE), self-directed learning (SDL), and AETCOM module in their log books. RW aimed to develop reflective thinking/reflective capacity among medical graduates to assist students in internalizing their learning in both cognitive and affective domains. The main objective of the study was to assess and compare the level of reflective thinking among first and second CBME batches of medical students using a self-administered structured questionnaire.

Methodology:
A self-administered questionnaire was shared with the students through Google Forms. A questionnaire was administered after the students were exposed to writing their reflections in the log books for each of their experiences in the foundation course, early clinical exposure, etc.

Results:
There were a total of 210 participants in the study, of which 151 of them belonged to Phase I, and 59 belonged to Phase II of MBBS. A mean score was then calculated for first- and second-year students for each of the four scales (understanding, habitual action, reflection, and critical reflection). The mean scores for habitual action and critical reflection are higher than those for understanding and reflection among Phase II medical students when compared to Phase I.

Conclusions:
This study provided insights from the students on their knowledge, attitude, and practice of reflective thinking among medical Phase I and Phase II medical students.
Expansile Lytic Lesion of the Proximal Phalanx of the Hand: A Diagnostic Enigma – A Case Report on Management with a Novel Technique
Authors: Manjunath N. , Reddy Danduru Vasudeva , Leo Latheesh 
Published: November 2024

Abstract
Expansile lesions in the hand mostly involve phalanges and metacarpals. Among them, majority comprising enchondroma and less incidence of aneurysmal bone cyst, giant cell tumor.The incidence of GCTs of hand bones is reported to be 2%. The authors report a case of an expansile lytic lesion involving the proximal phalanx of the right middle finger in a 22-year-old male. The lesion was excised en bloc, with reconstruction via a nonvascularized proximal phalanx graft of the 2nd toe and A2 pulley reconstruction via palmaris longus tendon. The diagnosis was confirmed by histopathological examination as GCT. The patient was followed for 10 months after surgery without any evidence of recurrence.
EXECUTION OF MORTGAGE RIGHTS THROUGH AUCTION IMPLEMENTATION WITHOUT COURT DECISION (STUDY OF SUPREME COURT DECISION NUMBER 3600 K/PDT/2020)
Authors: Dona Rahma , Setyono Yoni Agus 
Published: November 2024

The Law on Dependent Rights provides convenience and certainty for Holders of Dependent Rights to carry out execution through public auctions. The execution of the right of dependency can be carried out in two ways, namely the Execution Parate based on Article 6 of the Law on the Rights of Dependency, or through the Fiat of the District Court Execution based on Article 14 paragraphs (2) and (3) of the Law on the Rights of Dependency. In this writing, the main focus is to analyze the lawsuit against the defendant who is considered an unlawful act in the execution of the right of dependency through the implementation of an auction. This paper is expected to provide a comprehensive overview of the legal consequences arising from the existence of a civil lawsuit against the auction of the execution of the Right of Dependency and whether it is possible to conduct an auction without a court determination. The research used the doctrinal research method with the type of research used by the author based on its nature as an explanatory research, using case data in the Supreme Court Decision Number 3600 K/Pdt/2020 associated with principles, legal norms and laws and regulations. Lawsuits and fights create legal uncertainty for the Holder of Dependent Rights, auction buyers and other parties related to the execution of Dependent Rights.
The Interplay Between Social Support, Emotional Distress, and Psychosocial Quality of Life Among Cancer Survivors: Advancing Progress Toward SDG 3
Authors: Ngwira Flemmings Fishani , Kondowe Wellman , Mkandawire Jessie 
Published: November 2024

Objective: Cancer survivors face unique psychosocial stressors which impact their health and well-being. This study explores the prevalence and effects of perceived social support and emotional distress on survivors' psychosocial quality of life (QoL) in achieving sustainable development goal (SDG) 3: good health and well-being.

Theoretical Framework: This study employs the social support theory which emphasizes the importance of social support systems in improving psychological well-being and coping with stress. The study further uses the stress and coping theory which focuses on how individuals cope with stress.

Method: This study recruited 120 cancer patients receiving treatment at Queen Elizabeth Central Hospital and Kamuzu Central Hospital. Perceived social support and emotional distress were measured using the Berlin Social Support Scales (BSSS) and the Depression Anxiety and Stress Scales (DASS-21). Data analysis was performed using IBM® SPSS® Statistics version 22.

Results and Discussion: Survivors reported higher emotional support but lower informational support, with moderate levels of instrumental support, anxiety, depression, and QoL. Social support was positively linked to QoL, while emotional distress negatively impacted it. Additionally, anxiety and depression partially mediated the relationship between social support and QoL.

Research Implications: This study emphasizes the importance of social support in improving cancer survivors' quality of life and reducing emotional distress. It suggests that healthcare providers should focus on both emotional and instrumental support to better address survivors' mental health needs.

Originality/Value: The study highlights the greater importance of social support, and by focusing on cancer survivors in Malawi, the research contributes important regional data to the global understanding of cancer survivorship.
Strategic Model for Reducing Stunting Rates Through Parenting Improvement In Indonesia: Supporting SDG 3 to Promote Good Health and Well-Being
Authors: Kania Ikeu , Karmila Mila , Rismayanti Ema , Ardiyanti Handrini , Tarigan Herlina , Supriliyani Ni Wayan 
Published: November 2024

Objective: Stunting remains a critical issue in Indonesia, with significant implications for the health and development of children under five. Poor parenting practices, including inadequate feeding, exclusive breastfeeding, and unhealthy living conditions, contribute to high stunting rates. This research aims to develop an innovative strategy for parenting improvement involving all stakeholders to reduce stunting rates, thereby supporting the achievement of SDG 3 for good health and well-being.

Theoretical Framework: Stunting is a condition where a child's height is below the development standard by more than two standard deviations, leading to long-term consequences such as reduced cognitive skills, frequent illnesses, and higher risk of diseases. Factors affecting nutritional status include food intake, infectious diseases, food availability, parenting practices, environmental sanitation, and access to healthcare. Effective parenting counseling is essential to enhance parenting practices and prevent stunting. Avoiding punishment and ostracism is crucial in child-rearing.

Method: The study employed a qualitative approach using case studies, with data collected through in-depth interviews with key members of the stunting task force across three provinces.
Results and Discussion: The findings indicate that parents lack awareness and responsibility regarding government standards for childcare, exclusive breastfeeding, and healthcare utilization. The study proposes a strategic model for stunting reduction through improved parenting practices, involving Penta Helix elements such as the community, universities, media, businesses, and government. This model aims to create a synergistic system involving all stakeholders.

Research Implications: The proposed model is expected to enhance multi-sectoral collaboration and effectively reduce stunting rates.

Originality/Value: The study contributes an integrated approach to stunting reduction, emphasizing the role of parenting improvement in achieving SDG 3.
Evaluation Methods of General Requirements Courses and their Role in Improving Academic Performance and Graduate Attributes Among Taif University Students: Implications for Achieving SDG 4
Authors: Saleh Shoeb Gamal , Okiely Samir Mohammed Akel 
Published: November 2024

Objectives: This study aims to investigate the impact of different evaluation methods on academic performance and graduate attributes among Taif University students.

Theoretical Framework: The research aligns with the strategic goal of Taif University, represented by the Deanship of Ancillary Studies, to equip graduates with competitive attributes that meet labor market demands through enhanced academic performance.

Method: Employing an analytical descriptive approach, the study utilized the Graduate Attribute Scale and analyzed the academic results of a randomly selected sample of 459 students. The participants’ performance in various general requirement courses was assessed across Levels One, Three, Five, Two, Four, and Six during the first semester.

Results and Discussion: The findings indicated a significant improvement in students’ academic performance at Level Five compared to Levels One and Three. This improvement was attributed to the diversity in evaluation methods applied. Additionally, graduate attributes demonstrated notable enhancement at Level Six compared to Levels Two and Four, correlating with the varied evaluation strategies implemented in general requirements courses. The study suggests that diversifying assessment approaches can positively influence both academic performance and the development of graduate attributes.

Research Implications: These results underscore the importance of implementing varied evaluation methods in university curricula to boost student capabilities and prepare them effectively for professional challenges.

Originality/Value: The study contributes to the academic field by providing empirical evidence on the positive role of diverse evaluation methods in enhancing student performance and graduate attributes, offering insights for curriculum designers and policymakers at higher education institutions. This aligns with the Sustainable Development Goal (SDG) 4, which promotes quality education and lifelong learning opportunities for all.
Fuzzy Quadripartitioned Neutrosophic Matrices in Strategy Finding
Authors: P.Sheeba Maybell  , S.Indhumathi  
Published: November 2024

Researchers have primarily proposed fuzzy oriented matrix theories have to model uncertainty for real-world decision- making (DM). Fuzzy neutrosophic soft matrix (FNSM) theory has been developed recently by combining the fuzzy neutrosophic set and soft set to handle the indeterminate information parametrically. The concept of fuzzy Quadripartitioned neutrosophic soft matrices are discussed. Some properties of trace, Determinant of a Fuzzy Quadripartitioned Neutrosophic Soft Matrix with some examples were discussed. An application of FQNSMS for Dimensionality reduction in data mining were discussed with an algorithm.
Effect of Student Welfare on Academic Achievement in Secondary Schools in Kakamega County, Kenya
Authors: Kisiang’ani Electine Ayiela , Wamocha Lydia , Buhere Pamela 
Published: November 2024

This study sought to investigate the effect of student welfare on student academic achievement in Kakamega County, Kenya. The research employed the production function theory. The study was conducted using a survey research design. This study took place in Kakamega County, which has thirteen sub-counties. The study focused on 423 secondary schools, which included 2 national schools, 2 national special schools, 28 extra county schools, 45 county schools, and 346 sub county schools. The target population included 423 Principals, 5514 teachers, and 182,893 learners, for a total of 188,830 respondents in Kakamega County secondary schools. Purposive sampling was used to choose special and national schools. The Yamane formula was used to determine a sample of 440 respondents. The study gathered data through interviews and questionnaires. A pilot study was conducted in Bungoma County to test the instruments' validity and reliability. Cronbach's alpha was employed as a statistical tool to assess reliability. The study analyzed data using a Regression analysis. The results indicated that most of the institutions have resources that included classrooms, laboratories, libraries and others however they were not adequate. The results further revealed that most of the schools have adequate number of teachers while a sizeable were still struggling with fewer teachers. On the study’s hypothesis, H01 that state that there is no statistically significant effect of student welfare on student academic achievements in Kakamega County, Kenya was rejected at p=0.000. The study found that most respondents in Kakamega County, Kenya have adequate institutional resources such as classrooms, laboratories, and libraries. However, the principals disagreed, stating that these facilities are not sufficient. The study found that when institutional resources are absent, the average student academic achievement score improves by 6.93%. The analysis also revealed a statistically significant relationship between institutional resources and academic achievement, rejecting the null hypothesis that there is no significant effect. The findings suggest that enhancing institutional resources significantly boosts academic achievement among students in the region. The study thus recommends that the Ministry of Education and other stakeholders to enhance funding for school infrastructure, learning materials, and teacher training to improve student achievement. That schools should invest in nutritional support, mental health services, financial assistance, and co-curricular activities to create a supportive learning environment. This can be achieved through clear policies and robust school guidance and counselling programmes.
ABORDAGEM DO ENFERMEIRO NA ESTRATÉGIA SAÚDE FAMÍLIA PARA A PRÁTICA DE EXERCÍCIOS FÍSICOS NA PREVENÇÃO DA OBESIDADE EM ADULTOS
Authors: Reis Denise Gomes dos , Santos Carlos Oliveira 
Published: November 2024

Introdução: A obesidade é um problema de saúde pública crescente e global que afeta milhões de adultos em todo o mundo com impacto significativo na qualidade de vida e no aumento de doenças crônicas. O enfermeiro, como membro indispensável da Estratégia saúde em família, desempenha um papel crucial na implementação dessas intervenções, como a promoção de hábitos saudáveis, da prática de exercícios físicos e mudanças no estilo de vida. Objetivo: Este trabalho tem como objetivo principal descrever a importância da abordagem do enfermeiro na ESF, para a adesão da prática de exercícios físicos na população adulta, contribuindo para prevenção de doenças crônicas e outros agravos causados em decorrência desta doença como a hipertensão arterial sistêmica e diabetes mellitus. Materiais e Métodos: Este estudo foi desenvolvido a partir de uma revisão bibliográfica narrativa, efetuada na base de dados científicos como Medical Literature Analysis and Retrievel System Online (Medline) via United States National Library of Medicine (Pubmed), Scielo, Google Acadêmico com as seguintes palavras-chaves: ‘‘enfermagem’’, ‘‘obesidade’’, ‘‘prevenção’’, ‘‘estratégia saúde família’’. Resultados: Os resultados da revisão de literatura demonstram que a atuação dos enfermeiros da Estratégia de Saúde da Família (ESF) na promoção da prática de exercícios físicos como forma de prevenção da obesidade em adultos tem sido objeto de diversos estudos. Conclusão: O presente estudo evidenciou a importância da atuação do enfermeiro na Estratégia Saúde da Família (ESF) como promotor de saúde e agente facilitador na adoção de hábitos saudáveis, especialmente no incentivo à prática de exercícios físicos para a prevenção da obesidade em adultos. Conclui-se que a abordagem do enfermeiro na ESF deve ser ampliada e fortalecida para a prevenção da obesidade, uma vez que sua atuação educativa, aliada ao acompanhamento regular e ao apoio motivacional, pode gerar mudanças comportamentais significativas na população.
Pendekatan Integratif antara Perdata dan Pidana dalam Pengadilan Keluarga di Indonesia
Authors: Arrasyid Fauzan 
Published: November 2024

High rates of domestic violence and divorce highlight the need for a responsive and integrated justice system. This research aims to offer a family court model that integrates civil and criminal approaches in Indonesia. This normative legal research uses a comparative approach by comparing family court systems in other countries. Secondary data from various previous studies relevant to the subject matter. Data were collected through documentation techniques, and data were analysed using reduction, presentation, and verification techniques. The results of this study concluded that the existence of a family court system in Indonesia that combines civil and criminal approaches can demonstrate efficiency, consistency of decisions, and a focus on child welfare. The findings of this study can contribute to the paradigm of improving justice and welfare in the family court system in Indonesia.
A disciplina de Educação Especial na perspectiva inclusiva nos cursos de licenciatura em matemática: uma revisão sistemática de literatura
Authors: Melado Kariele Coutinho , Pinto Antônio Henrique , Thiengo Edmar Reis 
Published: November 2024

Este artigo apresenta uma Revisão Sistemática de Literatura, em âmbito nacional, que analisou o panorama de produções científicas, no período de 2008 a 2023, no que se refere à licenciatura em matemática com foco na disciplina de Educação Especial, na perspectiva inclusiva. Procedeu-se a um estudo qualitativo, seguindo a metodologia de Galvão e Ricarte, e as fases e etapas de seleção e análise de pesquisas em bases de dados por meio da planilha BUSCAd. Os resultados revelaram uma carência de trabalhos envolvendo a abordagem inclusiva na graduação em matemática, apontando uma insuficiência na formação inicial no que se refere ao trabalho com pessoas com deficiência. Ademais, não se verificaram pesquisas que abordam a formação inicial em matemática, fundamentada em políticas públicas inclusivas, em concepções sócio-históricas e nas relações da sociedade com este público, o que evidencia a necessidade de investigação nesse campo.
The Effectiveness of Autologous Composition Based on Dendritic Cells in the Treatment of Pulmonary Tuberculosis with Extremely Drug Resistance After an Ineffective Course of Polychemotherapy
Authors: Filatov M. V. , Starshinova A. A. , Nazarenko M. M. , Zinchenko Yu. S. , Istomina E. V. , Belaeva E. N. , Landa S. B. , Burdakov V. V. , Pavlova M. V. , Yablonskiy P. K. 
Published: November 2024

Despite the introduction of new anti-tuberculosis drugs, the problem of treating tuberculosis patients with a broad drug-resistant pathogen (XDR MBT) remains relevant.Aim of the study. Тo increase the effectiveness of treatment of this category of patients using an autologous composition based on dendritic cells activated by a specific antigen.Research materials and methods. А prospective study conducted in 2016-2019 included 52 patients, 36 (69.2%) men and 16 (30.8%) women, average age 43.2 ± 1.5 years. All patients received antituberculosis therapy in accordance with existing regulatory documents and recommendations. The main group consisted of 25 patients (48.1%) who agreed to immunotherapy with the introduction of an autologous composition with activated specific peptides ESAT-6 and SFP-10 dendritic cells against the background of anti-tuberculosis therapy. Statistical processing of the material carried out using the Statistica 10.0 application software package.Results. In 70.0% of cases (n = 14), there were no adverse reactions to suspension administration in patients of the main group. One patient (7.2%) had a general reaction in the form of tremor, chills after the first injection. In 5 (38.7%) patients on the 8th and 9th administration, a skin reaction was noted at the injection sites in the form of a papule, with a final regression of these changes after 8 weeks. By 18– 24 months of the course, anti-tuberculosis therapy in combination with immunotherapy in the first month of treatment allowed to obtain a positive effect according to clinical, bacteriological and radiological data in 64% of cases. It was not possible to obtain this result during therapy at the previous stages of treatment. In the comparison group, a positive result achieved only in 45.5% of cases.Conclusion. The results of the study suggest a positive effect of complex treatment with the inclusion of immunotherapy with an autologous composition based on dendritic cells in the most severe contingent of patients with pulmonary tuberculosis with broad drug resistance of the pathogen, even with an ineffective course of chemotherapy at the previous stage in 64% of cases.