bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novas práticas pedagógicas: considerações sobre transformações escolares a partir da atuação de docentes do Núcleo Takinahakỹ
Authors: NAZARENO Elias 
Published: December 2018

Desde o início do processo de colonização do Brasil, aproximadamente em 1532, a educação escolar indígena foi considerada como estratégica para o projeto de colonização e subalternização dos povos indígenas brasileiros. Não por acaso, essa tarefa foi delegada às ordens religiosas, sobretudo à jesuíta, pois elas detinham, além do monopólio em relação à produção do conhecimento e sua divulgação, o poder espiritual, por meio do cristianismo, e a chancela, por parte do Estado português, para que atuassem de forma uníssona com os interesses políticos, econômicos e expansionistas desse Estado. Temos, assim, dois pilares básicos em tal projeto de colonização: a educação escolar, com base nos valores ocidentais, e a cristianização ou catequização dos povos indígenas. New pedagogical practices: considerations about school transformations based on the work of teachers of the Takinahaky Nucleus
EMPOWERMENT OF FISHING COMMUNITY BUSINESS GROUPS IN KALIBARU VILLAGE, CILINCING, NORTH JAKARTA
Authors: Giyatmi Giyatmi , Basriman Iman , Siswanto Abdul Harif , Irianto Hari Eko 
Published: December 2018

The purpose of this activity was to empower fishing communities in Kalibaru, Cilincing through introducing knowledge of food handling and processing technologies, especially green mussels-based products. The partner involved in this study was the Annisa Bakti Business Group having 15 members of single parents. The profession of family members was green mussels peeler. Peeling process performed was through boiling, peeling the shell, icing, and then selling. The handling of green mussels with peeling was mainly intended to solve the problem overproduction which was not absorbed by the market as life green mussels. The appearance of peeled green mussels were usually pale, and the peeler usually introduced synthetic dyes to make them more attractive. The types of dyes used are generally not allowed for food because they are harmful to health. Based on those facts, the community empowerment efforts were carried out through the following ways: (1) Building motivation to develop the business; (2) More hygienic handling of green mussels; (3) Training on oyster (mussels) sauce processing; (4) Development of processed mussels product business, through introducing simple business feasibility study, business management, and simple financial bookkeeping. The program is expected to have an impact on improving the welfare of partners, especially the Annisa Bakti. Business Groups.
Detecting Outliers In Multiple Linear Regression
Authors: عبد السلام ايهاب 
Published: December 2018

It is well-known that the existence of outliers in the data will adversely affect the efficiency of estimation and results of the current study. In this paper four methods will be studied to detect outliers for the multiple linear regression model in two cases : first, in real data; and secondly, after adding the outliers to data and the attempt to detect it. The study is conducted for samples with different sizes, and uses three measures for comparing between these methods . These three measures are : the mask, dumping and standard error of the estimate.
متطلبات ادارة الموهبة في منظمات الاحتواء العالي : دراسة ميدانية في وزارة العلوم والتكنولوجيا
Authors: ابراهيم نور خليل , سعد خالد سلمان 
Published: December 2018

تشكل الموارد البشرية اليوم أهم الموارد التي تمتلكها المنظمة، اذ قد تمتلك الموارد المالية والتكنولوجية المتطورة للوصول إلى أهدافها، الا أنها لا تتمكن من استخدامها بالكفاءة والفاعلية المطلوبة وبالجودة المنشودة ما لم يكن هناك موارد بشرية ذات مهارات وخبرات ومواهب جيدة قادرة على توجيهها واستغلالها بالشكل الأمثل الذي يتوافق مع متطلبات السوق، حيث ان الأسواق اليوم ومنظمات الإعمال فيه تتنافس بطبيعة المواهب الكامنة فيها ، لذا فان مهمة استقطاب وتطوير الموارد الموهوبة والحفاظ عليها من التحديات التي تواجه المنظمات.
وسعى البحث إلى تحقيق مجموعة من الأهداف منها تشخيص متطلبات إدارة الموهبة في منظمات الاحتواء العالي كما انطلقت مشكلة البحث من واقع المنظمات وأهميتها في ظل تزايد المنافسة على المواهب، وان الشكل الوحيد القوي وغير قابل للتقليد في الميزة التنافسية هي الموهبة التي تستطيع المنظمة امتلاكها من خلال ثقافتها وان جاذبية القيم القوية والمواهب المنفتحة والتحيز الفكري والممارسات القوية، ستجلب وتحتفظ بأفضل الإفراد فيها، ان منظمات اليوم أخذت تحقيق التغير الثقافي لاعن طريق المصادفه، بل من خلال اعتماد إستراتيجية محددة للاحتواء العالي وخطة عمل قابلة للقياس. ولذا، فان ممارسات الاحتواء العالي تكمن في ايجاد الاحتواء العالي والموهبة ونشرهما او اشاعتهما بين العاملين. وذلك من خلال اختبار العاملين المناسبين للمنظمة والالتزام في التدريب وتطوير المهارات واعتماد نظم المشاركة في اتخاذ القرار ومشاركة المعلومات وكذلك نظم المشاركة في العوائد
PENERAPAN METODE CERTAINTY FACTOR UNTUK SISTEM PAKAR DIAGNOSA PENYAKIT DIABETES MELITUS PADA RSUD BUMI PANUA KABUPATEN POHUWATO
Authors: Riadi Annahl 
Published: December 2018

Diabetes Melitus (DM) atau biasa disebut diabetes merupakan penyakit gangguan metabolik menahun akibat pankreas tidak memproduksi cukup insulin atau tubuh tidak dapat menggunakan insulin yang diproduksi secara efektif. Penderita Diabetes Melitus di Kabupaten Pohuwato mengalami peningkatan sebanyak 8,5% setiap Tahun. Sistem pakar adalah program komputer yang menirukan penalaran seorang pakar dengan keahlian pada suatu wilayah pengetahuan tertentu. Sistem pakar mencoba mencari solusi, memberikan saran atau kesimpulan yang konsisten terhadap permasalahan yang ditemukannya. Penelitian ini akan dirancang menggunakan Aplikasi Dreamweaver dan bahasa pemrograman PHP, serta database MySQL. Harapan penulis, sistem ini dapat membantu masyarakat dalam mendiagnosa penyakit Diabetes Melitus. Melalui aplikasi ini, pengguna dapat melakukan konsultasi dengan sistem layaknya berkonsultasi dengan seorang pakar untuk mendiagnosa gejala yang terjadi pada pengguna serta menemukan solusi atas permasalahan yang dihadapi. Hasil pengujian sistem diperoleh nilai Cylomatic complexity = 5 dengan jumlah Region (R)= 5, Node (N)= 10, Edge (E)=13 Predicate Node (P) = 4.
Assessment of Proteinuria in Nephrotic Syndrome in Children by Using Spot Urinary Protein/Creatinine Ratio
Authors: Hossain Delowar , Zahiruddin - , Hoque Monimul 
Published: December 2018

Background: Quantification of proteinuria is usually predicted upon 24-hour urine collection. Multiple factors influence urine collection and the rate of protein and creatinine excretion. A spot urine protein-creatinine (P-C) ratio has been shown over the years to be a reliable alternative to the 24-hour collection for detection and follow up of proteinuria. The objective of the study was to evaluate the accuracy of urine protein creatinine ratio (UP/UC) in a spot sample for quantitative measurement of proteinuria in comparison with 24 hours urinary protein excretion in children of nephrotic syndrome having normal Glomerular Filtration Rate (GFR).
Methodology: This was a prospective study conducted in the department of paediatrics, Sir Salimullah Medical College & Mitford Hospital Dhaka over a period of six months from January 2003. Fifty cases of Nephrotic syndrome were included who were on initial attack and relapse cases noted down into the proforma with respect to history, examination and investigation. All the patients were advised regarding 24 hours urine collection. They were asked to give a 24 hours urine sample starting at 9.00 am for total protein excretion rate. A spot urine sample was obtained and urine protein/creatinine ratio was calculated. The data was analyzed by linear regression and by calculating the correlation coefficient between urinary protein/ creatinine ratio and 24-hour urinary protein.
Results: Sample size was fifty. Urine total protein in a timed 24-hour sample of nephrotic syndrome patients was in the range of 300-3150mg/m2/hour with the mean value of 1725 mg/m2/hour. While as U(Pr/Cr) ratio ranged from 3.1-27.5 with the mean value of 15.2. A significant correlation was found between timed 24-hour urinary protein and UP/UC ratio (r=0.622, p=<.001.)
Conclusions: Spot urine protein-creatinine ratio is highly reliable and rapid test for quantification of proteinuria in children with nephrotic syndrome.
Bangladesh J Child Health 2018; VOL 42 (3) :108-111
Neonatal Pneumonia in NICU of a Tertiary Care Center
Authors: Mannan MA , Nahar Nazmun , Ahmed Firoz , Jahan Ismat , Mosleh Taskina , Khan Kamrul Ahsan , Dey Sanjoy Kumer , Shahidullah Mohammod 
Published: December 2018

Background: Pneumonia is one of the causes of neonatal infection and responsible for significant morbidity and mortality, especially in developing countries. The study was aimed to reveal frequency and outcome of pneumonia among hospitalized sick newborn of neonatal intensive care unit.
Methodology: This observational study was carried out in the NICU of Bangabandhu Sheikh Mujib Medical University (BSMMU) on 94 neonates with the diagnosis of pneumonia admitted from July 2012 to June 2014. All studied neonates were subjected to history taking, clinical examination, routine investigations, chest radiography and blood culture and sensitivity.
Results: Incidence of neonatal pneumonia was 43% among admitted neonates with respiratory distress. Mean birth weight and gestational age were 2392±854 and 33±3.9 weeks respectively. Of enrolled infants with pneumonia, 38 (40.4%) were early onset, 24 (25%) were hospital acquired pneumonia and community acquired pneumonia was documented in 14 (14.8 %) and the rest 18 (19%) were ventilator associated pneumonia. Blood culture was positive in 18 (19%) of cases with neonatal pneumonia; most common pathogen isolated was acinetobacter. Mean duration of hospital stay was 19±8 days. Most of the neonatal pneumonia were cured 72 (76%) with therapy, whereas 17 (18%) died during their hospital course.
Conclusion: Overall incidence among admitted sick neonates was 8.4% which constituted 34% of distressed neonate.
Bangladesh J Child Health 2018; VOL 42 (3) :112-117
Progressive Myoclonic Epilepsy: Review Article with A Case Report of Lafora Disease
Authors: Banu Selina Husna , Koli Mashaya Zaman 
Published: December 2018

Progressive myoclonic epilepsy (PME) is an autosomal recessive, apparently a rare complex epilepsy syndrome. Among different types of PME, lafora body disease is more quickly progressive usually fatal within 2nd and 3rd decade. They are characterized by childhood or adolescent onset difficult to control multiple type seizures including myoclonous, generalized tonic clonic, absences, psychomotor regression with ataxia, dementia, dysarthria, visual hallucinations, and other general features. Early suspicion is important that leads to the rational diagnostic workout. The electro-clinical criteria would help a lot to exclude the benign epilepsy syndrome such as juvenile myoclonic epilepsy (JME) and suspect PME at the early stage of the complex epilepsy syndrome. Diagnosis is further clarified and confirmed by finding lafora body in skin and genetic study. Genetic mutation found in more than 87% cases in EPM2A gene or the EPM2B also known as NHLRC1 gene and are inherited in an autosomal recessive manner. EMP2A gene is located on chromosome 6q24. They are reported from Mediterranean basin, central Asia, India, Pakistan, northern Africa and Middle East where consanguineous marriage is common. We report a diagnosed case for the first time in Bangladesh. With the detail clinical history, rational use of the available investigation tools and clinical suspicion, diagnosis of the disorder at its early stage is possible. The rapid progress in genetic therapy would be a great hope in near future.
Bangladesh J Child Health 2018; VOL 42 (3) :138-147
The Mismeasure of Mergers: Revised Limits on Self-interacting Dark Matter in Merging Galaxy Clusters
Authors: Wittman David , Golovich Nathan , Dawson William A. 
Published: December 2018

Abstract
In an influential recent paper, Harvey et al. derive an upper limit to the self-interaction cross section of dark matter (DM) (

σ

DM

/

m

< 0.47 cm2 g−1 at 95% confidence) by averaging the DM–galaxy offsets in a sample of merging galaxy clusters. Using much more comprehensive data on the same clusters, we identify several substantial errors in their offset measurements. Correcting these errors relaxes the upper limit on

σ

DM

/

m

to ≲2 cm2 g−1, following the Harvey et al. prescription for relating offsets to cross sections in a simple solid-body scattering model. Furthermore, many clusters in the sample violate the assumptions behind this prescription, so even this revised upper limit should be used with caution. Although this particular sample does not tightly constrain self-interacting DM models when analyzed this way, we discuss how merger ensembles may be used more effectively in the future. We conclude that errors inherent in using single-band imaging to identify mass and light peaks do not necessarily average out in a sample of this size, particularly when a handful of substructures constitute a majority of the weight in the ensemble.
Photospheric Emission from Variable Engine Gamma-Ray Burst Simulations
Authors: Parsotan Tyler , López-Cámara Diego , Lazzati Davide 
Published: December 2018

Abstract
By coupling radiation transfer calculations to hydrodynamic simulations, there have been major advancements in understanding the long gamma-ray burst (LGRB) prompt emission. Building upon these achievements, we present an analysis of photospheric emission acquired by using the Monte Carlo Radiation Transfer (MCRaT) code on hydrodynamic simulations with variable jet profiles. MCRaT propagates and Compton-scatters individual photons that have been injected into the collimated outflow in order to produce synthetic light curves and spectra. These light curves and spectra allow us to compare our results to LGRB observational data. We find excellent agreement between our fitted time-resolved β parameters and those that are observed. Additionally, our simulations show that photospheric emission, under certain conditions, is able to create the observationally expected Band α parameter. Finally, we show that the simulations are consistent with the Golenetskii correlation but exhibit some strain with the Amati and Yonetoku correlations.
A SOFIA Survey of [C ii] in the Galaxy M51. I. [C ii] as a Tracer of Star Formation
Authors: Pineda Jorge L. , Fischer Christian , Kapala Maria , Stutzki Jürgen , Buchbender Christof , Goldsmith Paul F. , Ziebart Monika , Glover Simon C. O. , Klessen Ralf S. , Koda Jin , Kramer Carsten , Mookerjea Bhaswati , Sandstrom Karin , Scoville Nick , Smith Rowan 
Published: December 2018

Abstract
We present a [C ii] 158 μm map of the entire M51 (including M51b) grand design spiral galaxy observed with the Far Infrared Field-Imaging Line Spectrometer (FIFI-LS) instrument on board the Stratospheric Observatory For Infrared Astronomy (SOFIA). We compare the [C ii] emission with the total far-infrared (TIR) intensity and star formation rate (SFR) surface density maps (derived using Hα and 24 μm emission) to study the relationship between [C ii] and the star formation activity in a variety of environments within M51 on scales of 16″ corresponding to ∼660 pc. We find that [C ii] and the SFR surface density are well correlated in the central, spiral arm, and inter-arm regions. The correlation is in good agreement with that found for a larger sample of nearby galaxies at kpc scales. We find that the SFR, and [C ii] and TIR luminosities in M51, are dominated by the extended emission in M51's disk. The companion galaxy M51b, however, shows a deficit of [C ii] emission compared with the TIR emission and SFR surface density, with [C ii] emission detected only in the SW part of this galaxy. The [C ii] deficit is associated with an enhanced dust temperature in this galaxy. We interpret the faint [C ii] emission in M51b to be a result of suppressed star formation in this galaxy, while the bright mid- and far-infrared emission, which drive the TIR and SFR values, are powered by other mechanisms. A similar but less-pronounced effect is seen at the location of the black hole in M51's center. The observed [C ii] deficit in M51b suggests that this galaxy is a valuable laboratory to study the origin of the apparent [C ii] deficit observed in ultra-luminous galaxies.
Observations of Spin-down in Post-mass-transfer Stars and the Possibility for Blue Straggler Gyrochronology
Authors: Leiner Emily , Mathieu Robert D. , Gosnell Natalie M. , Sills Alison 
Published: December 2018

Abstract
Blue stragglers and other mass transfer/collision products are likely born with rapid rotation rates due to angular momentum transfer during mass-transfer, merger, or collisional formation. However, less is known about the angular momentum evolution of these stars as they age. Here we compare rotation rates and post-formation ages of mass-transfer products to models of angular momentum evolution for normal main-sequence (MS) stars and collisionally formed blue stragglers. In our sample, we include both F- and G-type blue stragglers in the cluster NGC 188 and post-mass-transfer GK MS stars in the field, all binaries with white dwarf (WD) companions. We compare ages derived from WD cooling models to photometric rotation periods and/or spectral v sin i measurements. We demonstrate that these systems have rapid rotation rates soon after formation. They then spin down as they age, much like standard solar-type MS stars do. We discuss the physical implications of this result, which suggests that the spin-down of post-mass transfer stars can be described by standard magnetic-braking prescriptions. This opens up the possibility of using gyrochronology as a method to determine the time since formation of blue straggler stars and other post-mass-transfer binaries.
Charcot–Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1β Inflammation in Human Macrophages
Authors: Rodríguez-Alcázar Juan Francisco , Ataide Marco Antonio , Engels Gudrun , Schmitt-Mabmunyo Christine , Garbi Natalio , Kastenmüller Wolfgang , Latz Eicke , Franklin Bernardo S. 
Published: December 2018

Abstract
Charcot–Leyden crystals (CLCs) are Galectin-10 protein crystals that can form after eosinophils degranulate. CLCs can appear and persist in tissues from patients with eosinophilic disorders, such as asthma, allergic reactions, and fungal and helminthic infections. Despite abundant reports of their occurrence in human disease, the inflammatory potential of CLCs has remained unknown. In this article, we show that CLCs induce the release of the proinflammatory cytokine IL-1β upon their phagocytosis by primary human macrophages in vitro. Chemical inhibition and small interfering RNA knockdown of NLRP3 in primary human macrophages abrogated their IL-1β response to CLCs. Using C57BL/6 ASC-mCitrine transgenic inflammasome reporter mice, we showed that the instillation of CLCs into the lungs promoted the assembly of ASC complexes in infiltrating immune cells (neutrophils and inflammatory monocytes) and resulted in IL-1β accumulation into the bronchoalveolar lavage fluid. Our findings reveal that CLCs are recognized by the NLRP3 inflammasome, which may sustain inflammation that follows eosinophilic inflammatory processes.
The Vacuolar Pathway of Long Peptide Cross-Presentation Can Be TAP Dependent
Authors: Ma Wenbin , Stroobant Vincent , Heirman Carlo , Sun Zhaojun , Thielemans Kris , Mulder Arend , van der Bruggen Pierre , Van den Eynde Benoît J. 
Published: December 2018

Abstract
The intracellular pathway of cross-presentation, which allows MHC class I–restricted presentation of peptides derived from exogenous Ags, remains poorly defined and may vary with the nature of the exogenous Ag and the type of APC. It can be cytosolic, characterized by proteasome and TAP dependency, or vacuolar, usually believed to be proteasome and TAP independent. Cross-presentation is particularly effective with long synthetic peptides, and we previously reported that the HLA-A2–restricted cross-presentation of a long peptide derived from melanoma Ag gp100 by human monocyte-derived immature dendritic cells occurred in a vacuolar pathway, making use of newly synthesized HLA-A2 molecules that follow a nonclassical secretion route. In this article, we show that the HLA-A1–restricted cross-presentation of a long peptide derived from tumor Ag MAGE-A3 by human monocyte-derived immature dendritic cells also follows a vacuolar pathway. However, as opposed to the HLA-A2–restricted peptide, cross-presentation of the HLA-A1–restricted peptide is TAP dependent. We show that this paradoxical TAP-dependency is indirect and reflects the need for TAP to load HLA-A1 molecules with peptides in the endoplasmic reticulum, to allow them to escape the endoplasmic reticulum and reach the vacuole, where peptide exchange with the cross-presented peptide likely occurs. Our results confirm and extend the involvement of the vacuolar pathway in the cross-presentation of long peptides, and indicate that TAP-dependency can no longer be used as a key criterion to distinguish the cytosolic from the vacuolar pathway of cross-presentation. They also stress the existence of an alternative secretory route for MHC class I, which will be worthy of further studies.
Adult education in Croatia after 1990
Authors: Žiljak Tihomir 
Published: December 2018

The main goal of the paper is to explain key elements of three cycles of adult education policy in Croatia from 1990 to 2018. The first cycles encompasses changes in the 1990s. The second begins in 2000 and is marked by the process of Europeanization within the process of Croatia’s accession to the European Union. The third begins with the accession of Croatia into the EU (2013) and with the passing of the Strategy of Education, Science and Technology (2014). In each cycle adult education policy instruments, actors, goals are analysed. In the last two cycles similar policy goals, instruments, actors as part of Europeanisation adult education policy are maintained, while first cycle is marked by political, ideological and institutional severing ties from the socialist education system. Final results of those processes are not satisfactory, and adult education is still marginalized with small participation in adult education.
High prevalence of anti-HEV antibodies among patients with immunosuppression and hepatic disorders in eastern Poland
Authors: Parfieniuk-Kowerda Anna , Jaroszewicz Jerzy , Łapiński Tadeusz W. , Łucejko Mariusz , Maciaszek Magdalena , Świderska Magdalena , Grzeszczuk Anna , Naumnik Beata , Rowiński Mirosław , Flisiak Robert 
Published: December 2018

IntroductionThe incidence of hepatitis E virus (HEV) infections in Poland is largely unknown. This study aimed to describe seroprevalence of markers of HEV infection among patients with immunodeficiency of diverse etiology and patients with advanced chronic liver diseases.Material and methodsFour hundred fifty patients were enrolled; among them, 180 persons were solid organ transplant recipients, 90 patients were HIV-infected and 180 persons had confirmed liver cirrhosis of different etiology. Serum anti-HEV-IgG, IgM antibodies and HEV-antigen were detected by ELISA (Wantai, China).ResultsIn the group of transplant recipients, serum anti-HEV-IgG antibodies were detected in 40.6%, IgM in 1.1% and HEV-Ag in 2.8% of subjects. In the HIV-infected population 37.7% had anti-HEV-IgG, 1.1% had anti-HEV-IgM and none had HEV-Ag. Among patients with advanced chronic liver diseases the highest prevalence of anti-HEV-IgG was recorded in alcohol-related liver cirrhosis (52.1%) (p = 0.049). In the population of all liver cirrhotics anti-HEV-IgG seroprevalence was 48.3%, anti-HEV-IgM seroprevalence was 5.0% and HEV-Ag seroprevalence was 1.7%. Older age and male gender were significant risk factors associated with increased anti-HEV-IgG prevalence, p = 0.0004 and p = 0.02, respectively.ConclusionsIn this large cohort a high seroprevalence of anti-HEV-IgG was detected in comparison to other European countries, with the highest rates in patients with alcoholic liver disease and in transplant recipients.