bluuebunny/crossref_metadata_2025_split huggingface dataset:
A REVIEW ON AYURVEDA PERSPECTIVE AND THERAPEUTIC CONSIDERATION OF OLIGOZOOSPERMIA
Authors: Chouhan Bhupendra Singh , Rajput Surendra Singh , Dwivedi Ramakant , Singh AK 
Published: November 2018

Male infertility is one of the burning problems now a day’s and incidences of this problem increases day by day due to the disturbed pattern of living style. The Oligozoospermia is one of the conditions related to male infertility which associated with low sperm count. Ayurveda the science of Indian medical system described various terms related to male infertility such as; Kshina shukra, Kshina retasa, Alpa retasa and Shukra dosha which resembles conditions associated with oligozoospermia. Ayurveda also described various treatment modalities for the management of oligozoospermia such as use of herbs & formulation, conduction of balanced life style and diet control, etc. This article presented a conclusive review on ayurveda perspective of oligozoospermia and its management.
Keywords: Ayurveda, Male Infertility, Oligozoospermia, Sperm, Vajikarana.
NOOTROPICS AGENTS: PHARMACEUTICAL ASPECT, COMMON EXAMPLES AND THEIR APPLICATIONS
Authors: Vitthalrao Leena Sakhare 
Published: November 2018

Nootropics compounds are one of the important categories of medicinal agents act as cognitive enhancers and neuroprotective. These agents mainly used to improve memory related functioning of brain. Nootropic compounds exhibited various neural activities and boost functioning of central nervous system including improvement of intellectual, memory and learning capacity. These agents also offer significant relief in various neurodegenerative disorders such as parkinson disease and alzheimer disease. Drugs, nutraceuticals, supplements and functional foods may be used as nootropics agents to enhance concentration and memory. Various synthetic & semi synthetic agents, material from natural origin such as; herbs, animal products and minerals may also act as potent nootropic agents. This article presented a pharmaceutical consideration of nootropic agents in a view to explore this area for future perspective.
Keywords: Nootropics, Memory, Cognitive, Brain, Neuroprotective
CHEMICAL PENETRATION ENHANCERS FOR TRANSDERMAL DRUG DELIVERY SYSTEM
Authors: Kapoor Anupriya , Mishra Shashi Kiran , Verma Dharmesh Kumar , Pandey Prashant 
Published: November 2018

In present scenario more than 70% of the drugs that are taken by oral route are found to be less effective as desired, to overcome this constraint Transdermal drug delivery system has emerged as an innovative area of research, this system helps in delivering the drugs and macromolecules through skin into systemic circulation. At present, the worldwide market of Transdermal patch has reached 2 billion pounds. Many drugs like Estrogen, Progestrone, Nitroglycerine, Clonodine etc. are fabricated in form of Transdermal patches due to its ability to deliver the drug in non-invasive manner and also to overcome the problems associated with oral route. Although the Transdermal patches deliver the drug at predetermined rate1, the partitioning of drug from the system to the skin and then penetration through different layers of skin can be altered by adding penetration enhancers that can be physical or chemical in nature. This article deals with the role of different chemicals that can be used as penetration enhancer.
Keywords: Penetration enhancer, Layer of skin, Fatty alcohol and glycol
AN EXTENSIVE REVIEW ON CHEMOTHERAPY INDUCED NAUSEA AND VOMITING
Authors: Bhulakshmi P , Nagaraju GV , Srilaya K 
Published: November 2018

Chemotherapy induced nausea and vomiting is the among most feared and debilitating adverse events experienced by the cancer patients. Left unaddressed, CINV symptoms not only decrease quality of life, but may also affect patients’ willingness to continue chemotherapy treatment. However, adherence to guideline recommendations continues to be suboptimal therapy, and many patients still suffer unnecessarily from CINV. In addition, breakthrough/refractory CINV continues to present particular challenges. The development of effective CINV treatments with diverse mechanisms of action has expanded the options available for preventing symptoms. The US Food and Drug Administration have recently approved several new therapies for the management of CINV. NEPA is a fixed-dose combination of Netupitant (300 mg) plus Palonosetron (0.5 mg). In combination with Dexamethasone, NEPA has demonstrated superior efficacy to Palonosetron alone in patients receiving highly or moderately emetogenic chemotherapy. Rolapitant is a nextgeneration neurokinin-1receptor antagonist. Both palonosetron and rolapitant have proven particularly effective in controlling delayed CINV. Regimens that combine a serotonin 5-hydroxytryptamine–3 receptor antagonist, an NK1 receptor antagonist, and a corticosteroid now represent the standard of care for managing both acute and delayed CINV in patients receiving highly emetogenic chemotherapy.
Keywords: CINV, Seratonin, Dopamine, Neurokinin, Antiemetics.
ANTI-SOLAR STUDY OF ETHANOLIC EXTRACT OF LEAVES CASSIA FISTULA
Authors: Gharge Varsha , Lokhande Tulashiram , Hadpad Shobha 
Published: November 2018

Objective: The present study aimed at the phytochemical examination and anti-solar activity of Cassia Fistula (leaf) Ethanolic extract has more Flavonoid content based on this chemical substance photo protective activity was evaluated using UV visible spectrophotometry, where the method is diffused transmittance and the range of UV-visible about 200-400nm.
Methods: The pulverized dried Cassia Fistula was extracted with ethanol using soxhlet apparatus. Ethanolic extract were filtered & evaporated to dryness. The photo protective activity was evaluated by using UV visible spectrophotometer, where the method it is diffused transmittance and the range of UV-visible about 200-400nm.
Results: The UV scanning absorption spectra of the extract showed very strong absorption at 0.265 A with λ max at 268 nm.
Conclusion: The extract has an ability to absorb in the entire UV range.
Keyword: UV rays, Cassia Fistula, Flavonoid content, ethanolic Extract, Anti-Solar
CONCEPT AND MANAGEMENT OF PREMENSTRUAL SYNDROME (MUTLAZIMA QABL HAIZ ) IN UNANI SYSTEM OF MEDICINE
Authors: Naushin Sofia , Ali Mubarak , Mustehasan Dr 
Published: November 2018

Mutlazima Qabl Haiz (Premenstrual syndrome) refers to a combination of physical and emotional disturbances that occur after a woman ovulates and resolves with start of menstruation. More than 200 symptoms have been ascribed to PMS. Premenstrual Dysphoric Disorder ia a more severe form of premenstrual syndrome. The characteristic symptoms of premenstrual syndrome are mood swings, anxiety, and irritability and physical conditions – like headache, fatigue, bloating, sleep disturbances, nausea, and breast tenderness. 90% of the women all over the world experience these symptoms during their reproductive years. The PMS has unknown cause and does not have any specific proved diagnosis and medication in modern medicine. The main objective of this article is to review the potential treatment for premenstrual syndrome in unani medicine.
Keywords: Premenstrual Syndrome, Premenstrual Dysphoric Syndrome, Unani Management
Clinical and Histological Study on Direct Pulp Capping With CO2 Laser Irradiation in Human Teeth
Authors: Suzuki M , Kato C , Kawashima S , Shinkai K 
Published: November 2018

SUMMARYThe study aimed to histologically evaluate wound healing of exposed human pulp on direct pulp capping using super-pulsed CO2 laser preirradiation. In this single-blind clinical trial, 28 third molar teeth of 17 volunteers were randomly capped with either CO2 laser irradiation (n=14) or Dycal (calcium hydroxide cement; n=14) and restored using resin composite. The laser was operated in super-pulsed mode (pulse duration, 0.2 ms; interval, 5.8 ms; 0.003 J/pulse). The irradiation conditions were a power output of 0.5 W, an irradiation time of 15 seconds, repeat mode (10-ms irradiation and 10-ms intervals, for a total beam exposure time of 7.5 seconds), total applied energy of 3.75 J, and an activated air-cooling system. Each tooth was extracted at six or 12 months posttreatment and prepared for histological evaluation. We evaluated the parameters of pulp tissue disorganization, inflammatory cell infiltration, reparative dentin formation (RDF), and bacterial penetration. There were no significant differences between groups for all parameters at each postoperative period (Mann-Whitney U-test, p&gt;0.05). CO2 laser irradiation completely controlled bleeding and exudate from the exposed pulp. The CO2 laser group had a tendency to delay RDF compared with the Dycal group, but 4 of 7 teeth from the CO2 laser group showed a complete dentin bridge at 12 months posttreatment.
Some Ecological and Human Lessons of Biosphere 2
Authors: Nelson Mark 
Published: November 2018

Abstract
The Biosphere 2 project, a 1.2 hectare materially-closed mini-biosphere that supported teams of biospherian crews from 1991-1994 provides a host of ecological and human-biosphere lessons relevant to our global biospheric challenges. Because of its high visibility through worldwide media coverage, the project advanced public understanding of what a biosphere is and the roles that humans can constructively play in keeping ecosystems and atmosphere healthy. The present paper reviews the fairly recent scientific understanding of our global biosphere and some of the intriguing results from Biosphere 2. It also examines some of the reasons that Biosphere 2 aroused controversy because of narrow definitions and expectations of how science is to be conducted. The cooperation between engineers and ecologists and the requirement to design a technosphere for Biosphere 2 that supported the life inside without harming it has enormous relevance to what is required in our global home. There was an unexpected and profound connection that the ‘biospherian’ crew inside Biosphere 2 felt to their living biosphere. Biosphere 2 also demonstrated new kinds of roles that can be played by people aware of a biosphere as their life support system.
The Meccan Era in the Light of the Turkish Writings from the Prophet’s Birth Till the Rise of the Mission - I
Authors: Al Harthy Noura Ahmed Hamed Al 
Published: November 2018

Abstract
The prophet’s biography had a supreme place in the Turkish writings. In this vein, the present research’s title is “The Meccan Era in the Turkish Writings from the prophet’s birth till the Prophetic Immigration to Medina”. Therefore in this research, a great amount of information about the Meccan era in the Turkish Writings from the prophet’s birth till the Prophetic Immigration to Medina was collected. It also included prophet’s life before and after the mission till the immigration to Abyssinia, the boycott, passing the second Aqaba Pledge, the Prophet's stand towards some contemporary nations and finally, the conclusion and the list of citied works and references. Before the prophet Muhammad Ibn Abd Allah's (PBUH) birth, the Arabian Peninsula lived in full darkness then it was enlightened by Islam. The prophet (PBUH) was not detached from the universal arena; rather, he was aware of the surrounding nations led by the Persians and Romans during that time. The Turks became in contact with Arabs from the earlier ages of the Islamic history. Moreover, the prophet sat in the Turkish tent and it is noticed that the Turkish Literature has paid great attention to the prophet’s biography, as well as the Meccan and Medina eras, since his childhood till his prophecy and all the details that related to the holy prophetic immigration to Medina, as we will see in the followings researches.
A Systematic Review on Psychosocial Determinants of Elderly Subjective Wellbeing
Authors: Hamid Tengku Aizan , Hassan Sumara Masood Ul , Haron Sharifah Azizah , Ibrahim Rahimah 
Published: November 2018

Abstract
The persistent increase in longevity has impelled social scientists to concentrate on the factors that can improve later life health and wellbeing. Extant literature indicates that filial responsibility, self-esteem, emotional regulation, attachment, parent-adult child relationship quality and religiosity are among those contributing factors for elderly subjective wellbeing. A systematic review was conducted to synthesize available evidence regarding the psychosocial determinants of elderly subjective wellbeing. Google Scholar, Science Direct and PubMed were searched for potentially relevant articles published from 2011 to 2017. Eighteen out of 216 full-text papers met the inclusion criteria and were critically appraised. The internal validity and quality of selected studies were assessed using STROBE and SIGN checklists. The findings of the current review suggest that filial responsibility, emotional regulation, self-esteem, attachment, and parent-adult child relationship quality were consistent determinants of elderly wellbeing; whereas findings on religiosity were equivocal. Further, self-esteem and emotional regulation emerged as significant cognitive-emotional underlying factors for the association between family relations and elderly wellbeing. In conclusion, despite methodological limitations of selected studies, this review was able to identify a number of psychosocial determinants of elderly subjective wellbeing. A comprehensive knowledge of these determining factors can contribute to a better understanding of empirical connections and identification of gaps in literature as well as directions for future studies.
Linear Structural Analysis of Media Management Administration, Innovation and Early Childhood Creative Technology Under the Office of the Basic Education Commission in Thailand
Authors: Pengruck Luckana , Boonphak Kanchana , Sisan Boonchan 
Published: November 2018

Abstract
The promotion of technological prowess in children at an early age is integral to their creative development and future success. This research studied the relationship between media management administration, innovation, and early childhood creative technology in schools under the Office of the Basic Education Commission in Thailand to validate and confirm the linear relationship between flexibility, motivation, imagination, use of new approaches to problem solving, and vision. Questionnaires from respondents showed that the consistency was between 0.60-1.00, with a reliability of 0.890. Data were analyzed using mean standard deviation, and linear structural analysis and compliance with empirical data was checked based on the harmony index which was then compared to applicable criteria. The major findings show that the composition is in line with the empirical data and demonstrated linear structural relationships between the components of media management administration, innovation and early childhood creative technology.
Yumurtacı Tavuk Rasyonlarına Kişniş Yağı (Coriander Oil) İlavesinin Performans, Yumurta Kalite Özellikleri, Yumurta Sarısı TBARS Değerleri ve Bazı Serum Parametreleri Üzerine Etkisi
Authors: ÇİFTÇİ Mehmet Emin , MACİT Muhlis 
Published: November 2018

Yumurtacı tavuk rasyonlarına kişniş yağı ilavesinin performans, yumurta kalite özellikleri, yumurta sarısı Tiyobarbitürik asit reaktif madde (TBARS) değerleri ve bazı serum parametreleri üzerine etkisini belirlemek amacıyla yürütülen çalışmada, her biri 24 adet hayvandan oluşan 1 kontrol ve 3 deneme grubu olmak üzere toplam 96 adet 24 haftalık yaşta Lohmann beyaz yumurtacı tavuk kullanılmıştır. Kontrol grubu (K-0) ticari yumurtacı tavuk yemiyle, diğer gruplar ise bazal yeme sırasıyla %0,1 (KY-1), %0,3 (KY-2) ve %0,5 (KY-3) düzeylerinde kişniş yağı ilavesiyle oluşturulan rasyonlarla 2 haftası deneme rasyonlarına alıştırma periyodu olmak üzere toplam 12 hafta süreyle beslenmiştir. Performans özelliklerinden günlük yem tüketimi, yemden yararlanma oranı ve hasarlı yumurta oranına muamelelerin etkisinin olmadığı (P&gt;0,05); ancak kontrole göretüm grupların yumurta verimini artırdığı (P&lt;0,01), yumurta ağırlığını ise azalttığı (P&lt;0,01) tespit edilmiştir. Yumurta kalite kriterleri üzerine muamelelerin etkisinin olmadığı (P&gt;0,05) görülmüştür. Kişniş yağı serum kan parametrelerinden kolesterol değerini (P&lt;0,01) düşürmesine rağmen diğer kan parametreleri muamelelerden etkilenmemiştir (P&gt;0,05). Yumurtaların depolama süresince (0, 7, 14 ve 28 gün) yumurta sarısı TBARS değerleri bakımından gruplar arasında anlamlı bir fark gözlenmemiştir (P&gt;0,05). K-0, KY-1, KY- 2 ve KY-3 gruplarının 0, 7, 14 ve 28. günlerdeki TBARS değerleri üzerine depolama zamanının etkisinin önemli olduğu saptanmış ve 28. gündeki TBARS değerinin önemli derecede yüksek olduğu belirlenmiştir.
Pobreza multidimensional en Chiapas: generalizada pero heterogénea
Authors: Aguilar Estrada Alma Esther , Caamal Cahuich Ignacio , Ortiz Rosales Miguel Ángel 
Published: November 2018

Aunque Chiapas ha sido un estado prioritario en combate a la pobreza, el 76% de la población persiste en esta situación. El objetivo de este trabajo es distinguir perfiles de pobreza a nivel municipal para la entidad y proponer políticas públicas diferenciadas. La metodología combina análisis multivariado y sistemas de información geográfica. Se obtuvieron cuatro perfiles de pobreza que se presentan con mapas y propuestas de política pública diferenciadas. Se concluye que la pobreza es un tema de interés prioritario en Chiapas, y que para lograr resultados es necesario considerar las particularidades de cada perfil y priorizar acciones particulares.
Medellín en su contexto eclesial
Authors: Codina Víctor 
Published: November 2018

Medellín 1968 fue un tiempo de gracia, una irrupción del Espíritu para América Latina, fue una recepción creativa del Vaticano II por parte de la Iglesia local Latinoamericana que en el clamor de los pobres discernió un signo de los tiempos En Medellín se actualiza el deseo de Juan XXIII de que el rostro de la Iglesia conciliar fuera el dela Iglesia de los pobres, que el Vaticano II, seguramente muy centro-europeo, no logró plasmar.Abstract: Medellin 1968 was a time of grace, an eruption of the Spirit for Latin America. It was a creative reception of the Vatican II by the local Latin-American Church that perceived in the outcry of the poor a sign of the times. In Medellin, Pope John XXIII’s wish – that the face of the conciliar Church be that of the Church of the poor – was finally concretized. This was a wish that the naturally very Centro-European Vatican II was unable to fulfil.Keywords: Vatican II; Local church; Signs of the times; Poor; Justice.
Study of Stylistic Functions of Pronoun in School (Based on the Material of the «Solntse Mertvyh» by I.S. Shmelev)
Authors: Demidova E. B. , Sharlikova L. G. 
Published: November 2018

Works by I.S. Shmelev due to the large educational and aesthetic potential inherent in them, can be widely used in the educational process.Some forms of plural pronouns are sometimes used in the «Solntse Mertvyh» to refer to those who for some reason do not follow or can not be called their own name.According to FGOS pronouns, in view of the high degree of repeatability of their load this text, can be proposed as an object of linguistic analysis in school.
Hubungan Antara Hardiness Dengan Burnout Pada Santri Pondok Pesantren Persatuan Islam Putra Bangil
Authors: Fahmi Abd. Rochman , Widyastuti Widyastuti 
Published: November 2018

<p>Density of boarding activities demanding students to do more intense routines. These routines can be a pressure for students that experienced mental fatigue of Burnout. Burnout can be affected by external factors or internals. Internals factors become very important because individual assessnebt against external factors depend on its internal factors. The method of this research is quantitative correlational by using the boarding school’s students as subjects. Determination of the subject use proporsionate stratified random sampling. The method of data collection is spread the questioner wich contain Hardiness and Burnout scale based on aspects of each variables. This research analyze the relationship of Hardiness as internal factor with Burnout on boarding school’s students. This research use quantitative correlational method with a scale of Hardiness and Burnout that distribute on 97 boarding school’s students. The result of this research are calculated using the correlational product moment, then obtained a very significant result with a value of correlational is – 0,714. Based on the result , the correlation between Hardiness and Bunrout has proven with a negative direction of hypothesis. Based on simple regression analysis on the results, obtained F of 92,664 with sig = 0.000 which sig &lt;0.05. The effective contribution of Hardiness against Burnout is 50.5%, the meaning there is still a 49.5% chance of Burnout is affected by other variables.<strong></strong></p>
Evaluation of surgical outcomes of arthroscopic subtalar arthrodesis performed through two lateral portals
Authors: Villela Rafael Freitas , Magalhães João Murilo Brandão , Gomes Rogério de Andrade , Gomes Anderson Humberto , Coelho Bernardo Cardoso Pinto , Fonseca Wagner Vieira da 
Published: November 2018

Objective: The purpose of this study is to present the surgical outcomes of twelve patients undergoing arthroscopic subtalar arthrodesis using two lateral portals (anterior and medial) in the sinus tarsi. Methods: A retrospective study was conducted with twelve patients (7 men and 5 women) with a mean age of 55.1 (36-74) years who underwent arthroscopic subtalar arthrodesis through the sinus tarsi between May 2015 and December 2016. The post-surgical follow-up was 12 months. Consolidation time and postoperative complications were evaluated, and a validated functional questionnaire from the American OrthopedicFoot and Ankle Society (AOFAS) and the visual analog scale (VAS) for pain were applied both before and after surgery. Results: The mean bone fusion time was 11.5 weeks. Bone consolidation was observed in all analyzed patients. Four patients developed late complications, three of which were related to screw positioning in the calcaneus, while one was related to residual hindfoot varus deformity. Screw-related complications are common with all subtalar arthrodesis techniques, and such complications are considered less relevant when evaluating the effectiveness of the presented technique. The mean preoperative AOFAS score was 42.3 (27-66) points, while the mean postoperative score was 83 (73-94) points. The mean preoperative VAS score for pain was 8.1 (5-10) points, and the mean postoperative score was 2.1 (0-5) points. The above data are similar to those reported in other published studies and reflect high bone consolidation rates. Conclusion: Arthroscopic subtalar arthrodesis through two lateral portals in the sinus tarsi is a safe and effective technique for the treatment of primary and secondary disorders of the subtalar joint. Correct positioning of screws and hindfoot alignment must be carefully ensured to avoid complications related to the synthesis material and hindfoot varus deformity. Level of Evidence IV; Therapeutic Studies; Case Series.