bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and outcomes of an immersive obesity summit workshop for medical resident and fellow education
Authors: Velazquez Amanda , Robinson Katie J. H. , Frederick Jennifer L. , Kushner Robert F. 
Published: June 2019

SummaryPhysicians need better training to manage patients with obesity. Our study capitalized on the intimate nature of an extracurricular obesity workshop, creating an interactive educational programme. We assessed the short‐ and long‐term impact of the workshop on trainees' knowledge, competence and confidence in caring for patients with obesity in an outpatient setting. This is a cross‐sectional study, involving regionally diverse mix of resident and fellow physicians. A live 2.5‐day continuing medical education summit was held 11 to 13 March 2016. Obesity‐related topics were reviewed using state‐of‐the art pedagogical techniques. Pre‐/post‐levels of knowledge, competence and clinical practice strategies were analysed. Sixty‐three candidates interested in additional obesity medicine training were nominated by US residency and fellowship programme directors and selected to attend the summit. On average, learners experienced a 110% relative increase in knowledge and competence. The overall effect size was 0.95, with participants being ~54% more knowledgeable about the management of patients with obesity. All participants self‐reported that this activity increased their knowledge about the subject matter, improving their performance in caring for patients when asked about their practice in a follow‐up survey 6 months following the workshop. This immersive summit promoted robust gains in knowledge and confidence, ultimately translating to reported practice improvements at the individual and health system levels. Future research is warranted on the sustainability of gained skills.
Light stability in cyan and magenta tones using standard and highly chromatic toner particles
Authors: Majnarić Igor , Morić Marko , Modrić Damir 
Published: June 2019

AbstractAn increasing requisite regarding the reproduction quality of electrophotographic printing machines demands improvement of new electrophotographic toner formulation, especially used pigments. The subject of this paper is a comparison of prints realised by depositing high chroma (HC) and standard emulsion aggregation (EA) toner on gloss fine art paper. HC toner has a different composition of the cyan and magenta tones compared with the corresponding standard EA toner tones and therefore behaves differently under real conditions. The patches used for this experiment were cyan and magenta tone prints with tone values (TVs) of 0, 20, 60 and 100%. Ultraviolet (UV) degradation was measured over time intervals of 0, 6, 12, 24, 48, 96, 144 and 240 h for all patches. Results (laboratory values) were calculated using colorimetric difference. Values were plotted as a function of time in tonal degradation graphs. A model was created using non‐linear regression‐based modelling. The experiment demonstrates that magenta patches are more susceptible to degradation in comparison with cyan patches. With the increase in tonal value, it is noticeable that the colorimetric difference is higher. Colorimetric differences calculated using HC magenta toner and standard EA cyan toner (100% TV) were higher than ∆E = 5, starting to appear after 6 h of exposure to UV radiance. After 12 h of exposure, colorimetric differences of standard magenta tones that were greater than ∆E = 5 also started to appear. Cyan patches (100% TV) printed with HC toner were more stable than the other patches, and after 240 h of exposure had not crossed the boundary of ∆E = 5.
Retraction of reconstructing disasters and adaptation scenario of nineteenth‐century Kashmir
Authors: Ahmad Bashir , Alam Akhtar , Bhat M. Sultan , Bhat Kurshid A. 
Published: June 2019

The above article from Disasters, published online on 24 June 2019 in Wiley Online Library (http://wileyonlinelibrary.com) has been withdrawn by agreement between the authors, the Journal Editors, Sara Pantuliano, John Twigg, Helen Young and Matthew Foley, and John Wiley & Sons Ltd., on behalf of Overseas Development Institute.ReferenceAhmad, B., Alam, A., Bhat, M. S. and Bhat, K. A. (2019), . Disasters. Accepted Author Manuscript. doi:10.1111/disa.12364
Upfront bortezomib, lenalidomide, and dexamethasone compared to bortezomib, cyclophosphamide, and dexamethasone in multiple myeloma
Authors: Uttervall Katarina , Borg Bruchfeld Johanna , Gran Charlotte , Wålinder Göran , Månsson Robert , Lund Johan , Gahrton Gösta , Alici Evren , Nahi Hareth 
Published: June 2019

AbstractObjectivesAt our center, patients with multiple myeloma (MM) were treated upfront with bortezomib, cyclophosphamide, and dexamethasone (VCD) until cyclophosphamide was replaced with lenalidomide in the combination (VRD). These treatments have never been compared head‐to‐head in large real‐life patient material.MethodA retrospective analysis of patients treated with VRD and VCD in the first line, both with and without subsequent high‐dose treatment (HDT) and autologous stem cell transplantation. A total of 681 patients were included, 117 receiving VRD (71 with, 46 without HDT) and 564 receiving VCD (351 with, 213 without HDT).ResultsOverall response rate (≥partial response) was higher with VRD compared to VCD in the entire VRD group (98% vs 88%, P < 0.001) and in the non‐HDT group (98% vs 79%, P < 0.001). Progression‐free survival (PFS) at 18 months was longer with VRD compared to VCD in the entire VRD group, the non‐HDT group and the HDT group (88% vs 63%, 82% vs 32% and 91% vs 73%, respectively). Overall survival at 18 months was better for VRD‐treated patients in the entire VRD group (95% vs 89%, P = 0.048).ConclusionUpfront VRD gives better responses and longer PFS compared to VCD in MM patients with or without subsequent HDT.
Expert system for problem solving in distance university education: The successful case of the subject “operations management”
Authors: de la Peña Esteban F. David , Lara Torralbo Juan A. , Lizcano Casas David , Martínez Rey María A. 
Published: June 2019

AbstractAcquiring the skills needed to solve certain types of problems is one of the main challenges of distance university education, demanding extra motivation from students to tackle it. New technology should be one of our great allies in addressing these problems. This article proposes an expert system with a web‐based problem‐solving simulator for a multidevice environment in order to allow students to access an unlimited number of problems with their corresponding solutions, immediately, anytime and anywhere. The types of problems that can be used are those based on quantitative methods with a fixed methodology to be followed. A successful case study was carried out for the subject Operations Management at the Distance University of Madrid (UDIMA), with three different problem simulators having been developed. The results were very satisfactory compared with previous academic years in terms of motivation. A decrease in students that did not sit the final examination was observed, as was an increase in the number of visits to the Moodle classroom. Students also responded positively in their assessments of the initiative.
Stem/progenitor cell‐mediated pulpal tissue regeneration: a systematic review and meta‐analysis
Authors: Fawzy El‐Sayed K. M. , Ahmed G. M. , Abouauf E. A. , Schwendicke F. 
Published: June 2019

AbstractBackgroundStem/progenitor cell‐mediated pulpal regeneration could represent a promising therapeutic alternative in the field of clinical endodontics.AimThe present study aimed to systematically assess and meta‐analyse dental pulpal tissue regeneration, pulpal vitality and apical healing after the transplantation of stem/progenitor cells versus no transplantation.Data sourcesMEDLINE, Cochrane CENTRAL and EMBASE were searched up to January 2019 for animal experiments and human trials evaluating the pulpal transplantation of stem/progenitor cells. Cross‐referencing and hand search were additionally performed.Study eligibility criteria, participants and interventionsBased on randomized controlled clinical trials (RCTs) or controlled clinical trials (CCTs), conducted in animals or humans, the effect of the transplantation of stem/progenitor cells compared to no transplantation on pulpal tissue regeneration, pulpal vitality and apical healing was examined.Study appraisal and synthesis methodsThe primary outcome was histologically determined pulpal tissue regeneration, whilst pulpal vitality and apical healing were secondary outcomes. The SYstematic Review Centre for Laboratory animal Experimentation (SYRCLE) guidelines and the revised Cochrane risk of bias tool (RoB 2.0) were used for risk‐of‐bias assessment. Pooled standardized differences in means (SDM) and 95% confidence intervals (95% CI) were calculated using random‐effects meta‐analyses.ResultsFrom 2834 identified articles, eight animal experiments (82 animals with 336 experimental pulpal defects) and one human trial (40 humans with 40 pulpal defects) were included. Risk of bias of most animal studies was high, whilst the human trial revealed ‘some concerns’. Stem/progenitor cell‐transplanted pulps demonstrated significantly increased pulpal tissue regeneration compared with controls (SDM [95%CI]: 6.29 [3.78–8.80]).LimitationsData on pulpal vitality and apical healing were sparse and inconsistent. Heterogeneity across studies was substantial, publication bias was present, and mainly indirect, surrogate outcome measures were applied. The overall strength of evidence was very low.Conclusions and implications of key findingsThe transplanation of stem/progenitor cells shows promise for pulp regeneration, whilst clinical routine application is still not in reach. Further investigations, employing a comprehensive set of outcomes including those demonstrating functional pulp regeneration relevant for patient‐centred care, are required.
A clinico‐demographic study of 344 patients with lichen planus pigmentosus seen in a tertiary care center in India over an 8‐year period
Authors: Vinay Keshavamurthy , Kumar Sheetanshu , Bishnoi Anuradha , Aggarwal Divya , Radotra Bishan Dass , Parsad Davinder , Sendhil Kumaran Muthu 
Published: June 2019

AbstractBackgroundLichen planus pigmentosus (LPP) is an acquired disorder of hyperpigmentation affecting certain racial and ethnic groups.ObjectiveTo retrospectively analyze the demographic and clinical characteristics of LPP.MethodsClinical and demographic records of all LPP patients attending our pigmentary clinic from January 2011 to June 2018 were reviewed.ResultsData of 344 LPP patients (229 females) were analyzed. Affected females had significantly higher age at onset (P < 0.002) but lesser disease duration at presentation (P < 0.001) as compared to males. Significant positive correlation between body surface area involvement and disease duration was observed (r = 0.72). Personal history of atopy and accompanying autoimmune diseases were observed in 49 (14.24%) and 45 (13.08%) patients, respectively. Observed morphological patterns of LPP included diffuse (n = 193, 56.1%); reticular (n = 45, 13.1%); blotchy (n = 41, 11.9%); and follicular (n = 28, 8.1%). All the patients had a chronic and indolent course of disease with approximately half (49.2%) reporting satisfactory improvement with treatment.ConclusionThis is the largest clinico‐demographic study till date on LPP. A longer disease duration was associated with more widespread disease. Although the disease improved over time as per patient and physician global assessment, a complete clearance was rarely attained.
Low concentration short time ozonation of rapeseed seeds reduces the stability of the oil and content of some antioxidant components
Authors: Jackowska Izabella , Bojanowska Monika , Staszowska‐Karkut Monika , Sachadyn‐Król Monika 
Published: June 2019

SummaryOzonation is an innovative way to preserve high quality of seed during storage and it is an alternative to harmful organophosphorus agents. Disclosure of changes in the rapeseed oil under the influence of oxidative action of ozone on the seeds was the aim of the work and is presented for the first time. Two ozone concentrations and different length of ozonation were applied. The changes in tocopherols, phenolics, flavonoids contents, antiradical activity and oxidative stability were examined. The average vitamin E concentration was 33 mg per 100 g of oil before and 31.7 after ozonation of seeds. The average content of phenolic compounds was 14.3 mg of sinapic acid g−1 and 16.9 after the ozone treatment. Changes in the flavonoids content and antioxidant activity were observed too. Ozonation caused a decrease in the vitamin E concentration which resulted also in reducing the quenching of free radicals and reduction of oil induction time.
Quality changes of pork during frozen storage: comparison of immersion solution freezing and air blast freezing
Authors: Hou Qin , Cheng Yu‐ping , Kang Da‐cheng , Zhang Wan‐gang , Zhou Guang‐hong 
Published: June 2019

SummaryThis study evaluated the effects of freezing method and storage time on the quality changes of pork longissimus thoracis (LT). The results showed that, compared to air blast freezing (AF), better microstructure was observed in pork under immersion solution freezing (ISF) mainly due to higher freezing rate. ISF group had significantly lower thawing loss at 1, 31 and 91 days and higher shear force at 1 day than AF (P < 0.05). A significant reduction in TBARS value at 61 and 91 days was observed in ISF samples (P < 0.05). No significant differences were observed between the two treatments in the colour, cooking loss and sulfhydryl groups (P > 0.05). All quality indicators were significantly affected by storage time (P < 0.05). It is concluded that ISF could maintain better microstructure, improve water‐holding capacity and inhibit lipid oxidation during pork LT frozen storage.
Effects of virgin coconut oil on the physicochemical, morphological and antibacterial properties of potato starch‐based biodegradable films
Authors: Fangfang Zhang , Xinpeng Bai , Wei Gao , Wang Guoding , Shi Zhenzhen , Jun Cao 
Published: June 2019

SummaryThis study investigated the effects of adding different concentrations of virgin coconut oil (VCO) on the optical, mechanical, thermodynamic and antimicrobial properties, as well as water vapour permeability and morphology of potato starch‐based biodegradable films. Increasing VCO concentrations caused a rise in the light transmittance of the films from 2.13 to 4.79 mm−1 and a decrease in water vapour transmittance from 6.77 to 2.12 (10−5 GPa−1 h−1 m−1). At a VCO concentration of 14 wt% (based on potato starch), the tensile strength reached its highest value (19.98 MPa). Scanning electron microscopy showed that the surface of the film became smoother as VCO concentration increased. The addition of VCO inhibited the growth of Listeria monocytogenes, Staphylococcus aureus and Escherichia coli. In conclusion, VCO supplementation improved the mechanical, antibacterial and water barrier properties of starch‐based films. These results could expand the scope of the application of starch‐based films in food packaging.
Thermal degradation kinetics of carotenoids, vitamin C and provitamin A in tree tomato juice
Authors: Ordóñez‐Santos Luis Eduardo , Martínez‐Girón Jader 
Published: June 2019

SummaryIn this research, the influence of temperature on the degradation of carotenoids, vitamin C and provitamin A in tree tomato juice was studied at 70, 80 and 90 °C. The thermal processing significantly reduced (P < 0.001) the concentration of the bioactive compounds, and the thermal degradation in the evaluated phytochemicals fit a kinetic first order, with the following activation energies (Ea, kJ mol−1): α‐carotene (69.75), β‐carotene (59.50), provitamin A (51.67), zeaxanthin (43.66), vitamin C (41.27), lycopene (18.84) and β‐cryptoxanthin (18.23). The kinetic study and thermodynamic analysis of the tree tomato juice showed that the degree of thermoresistance in the phytonutrients responded in the following order: β‐cryptoxanthin > lycopene > vitamin C > zeaxanthin > provitamin A > β‐carotene > α‐carotene. This study benefits engineering processes interested in the design and optimisation of thermal processes aimed at preserving the nutritional quality of tree tomato juice.
Burning out physical and emotional fatigue: Evaluating the effects of a programme aimed at reducing burnout among mental health nurses
Authors: Alenezi Atallah , McAndrew Sue , Fallon Paul 
Published: June 2019

AbstractBurnout is a common problem among mental health nurses. High levels of burnout result in job dissatisfaction, rapid turnover of staff, physical and psychological discomfort, and a reduction in the quality of patient care. While there is an abundance of research relating to burnout per se, research regarding the impact of burnout prevention programmes is lacking. This study aimed to measure the effects of a burnout prevention programme on mental health nurses working in Saudi Arabia (SA). A quasi‐experimental design was used to test the effectiveness of a two‐day burnout prevention workshop. The sample consisted of an intervention group (n = 154) and a control group (n = 142). Data collected using the Maslach Burnout Inventory (MBI) measured the effects of the workshop at 1‐, 3‐, and 6‐month intervals after completion of the programme. Data were analysed using the latest version of SPSS. Means, standard deviations, frequencies, and percentages were used to describe the sample and levels of burnout. A t‐test, ANOVA, multiple linear regression, and chi‐squared were used to measure the effect of the workshop before and at the three time points after exposure. Findings indicate the programme was effective with a significant reduction being reported 1 month after the intervention. However, although not returning to baseline scores, burnout scores had increased at 6 months. In conclusion, while the overall efficacy of the burnout reduction programme is evident, mental health nurses would benefit from having opportunity to use some of the strategies on a regular basis.
A safe and simple approach to avoid fast junctional rhythm during ablation in patients with atrioventricular nodal reentrant tachycardia
Authors: Tachibana Motomi , Banba Kimikazu , Matsumoto Kensuke , Ohara Minako , Nagase Satoshi 
Published: June 2019

AbstractIntroductionFast junctional rhythm (JR) during slow pathway modification for atrioventricular nodal reentrant tachycardia (AVNRT) is a predictor of serious atrioventricular block. This study investigated the boundary to avoid fast JR during ablation with three‐dimensional (3D) electroanatomical mapping in AVNRT patients.Methods and ResultsParticipants were 129 consecutive patients with common AVNRT who received anatomical ablation to an antegrade slow pathway at our institution between August 2013 and March 2019. Successfully ablated sites with JR were evaluated in terms of distances and angles in the left and right anterior oblique views (LAO and RAO, respectively) to the proximal His bundle (His) site using 3D mapping. We divided JR by heart rate: JR1 ≥150 bpm and JR2 <150 bpm. Average age was 61 ± 16 years; 41.1% of patients were male. The distance from the most proximal His to the JR1 and JR2 site was not significantly different (11.9 ± 4.4 vs 10.7 ± 4.5 mm, P = .24). JR1 predominantly appeared closer to the left ventricle than JR2 in LAO (110.5 ± 19.1° vs 77.5 ± 18.6°, P < .01), and was more posterior from the proximal His in RAO (30.8% vs 6.8%, P < .01). The vertical line drawn down from the proximal His in the LAO view was a good indicator of JR1 appearance (sensitivity and specificity 84.6% and 81.6%, respectively).ConclusionThe vertical line drawn down from the proximal His in the LAO view can be employed as a boundary to avoid fast JR during ablation in AVNRT.
European task force on atopic dermatitis position paper: treatment of parental atopic dermatitis during preconception, pregnancy and lactation period
Authors: Vestergaard C. , Wollenberg A. , Barbarot S. , Christen‐Zaech S. , Deleuran M. , Spuls P. , Flohr C. , Trzeciak M. , von Kobyletzki L. , Seneschal J. , Paul C. , Bieber T. , Werfel T. , Fölster‐Holst R. , Darsow U. , Gieler U. , Svensson Å. , Cork M. , Stalder J.‐F. , De Raeve L. , Kunz B. , Simon D. , Chernyshov P. , Hijnen D. , Gelmetti C. , Ring J. , Taieb A. , de Bruin‐Weller M. , Thyssen J.P. 
Published: June 2019

AbstractAtopic dermatitis (AD) is a common inflammatory skin disease that affects both children and adults, including a large number of adults of reproductive age. Several guidelines for the treatment of AD exist, yet specific recommendations for the treatment of pregnant or lactating women and for adults planning to have a child are often lacking. This position paper from the European Task force on Atopic Dermatitis (ETFAD) is based on up‐to‐date scientific literature on treating pregnant and lactating women as wells as adults with AD planning to have a child. It is based on the expert opinions of members of the ETFAD and on existing safety data on the proposed treatments, many of which are derived from patients with other inflammatory diseases or from transplantation medicine. For treating future parents, as well as pregnant and lactating women with AD, the use of topical treatments including moisturizers, topical corticosteroids, tacrolimus, antiseptics such as chlorhexidine, octenidine, potassium permanganate and sodium hypochlorite (bleach) is deemed to be safe. Ultraviolet (UV) therapy may also be used. Systemic treatment should be prescribed only after careful consideration. According to the opinion of the ETFAD, treatment should be restricted to systemic corticosteroids and cyclosporine A, and, in selected cases, azathioprine.
Secondary hosts of the Asian citrus psyllid, Diaphorina citri Kuwayama: Survivorship and preference
Authors: Johnston Nicholas , Stansly Philip A. , Stelinski Lukasz L. 
Published: June 2019

AbstractThe Asian citrus psyllid, Diaphorina citri Kuwayama, is the most economically important and difficult to manage citrus pest in Florida due to its role as vector of huanglongbing or citrus greening disease. Spread of the disease is a function of dispersal patterns and thus influenced by availability of suitable hosts. Young leaves of citrus or related plants are required for reproduction, but in their absence, secondary hosts may provide needed resources to enhance survival. Therefore, survivorship on and preference for three abundant weed species was investigated. The suitability of potential secondary host plants Bidens alba (L.), DC, Ludwigia octovalvis (Jacqu.) P. H. Raven, and Eupatorium capillifolium (Lam.) Small was compared to a reproductive host, Murraya paniculata (L.) Jack, in no‐choice tests by assessing survivorship of D. citri adults confined to these plants in cages. Preference was evaluated by choice tests where D. citri adults were released into cages containing all three secondary hosts alone or with M. paniculata. Both B. alba and E. capillifolium increased D. citri survivorship by twofold compared to starvation conditions with only water available. Choice trials revealed no difference in initial selection between true and secondary hosts; however, the true host was favoured over time. This result suggested that hosts were selected initially by sight, and only later by taste and/or smell. While secondary hosts are unable to support reproduction or long‐term survival, these findings establish the ability of D. citri to use secondary hosts that are ubiquitous in Florida citrus groves as temporary reservoirs for food and moisture when ideal host conditions are scarce or absent.