bluuebunny/crossref_metadata_2025_split huggingface dataset:
An adaptive approach for handling two‐dimension influence maximization in social networks
Authors: He Qiang , Wang Xingwei , Huang Min , Cai Yuliang , Zhang Chuangchuang , Ma Lianbo 
Published: August 2018

SummaryTo synthetically and dynamically make strategic choices in social networks, a novel adaptive approach to deal with two‐dimension influence maximization problem (TIMP) is proposed with game‐based diffusion model, which can achieve trade‐off between diffusion time and the number of active nodes. At first, TIMP model is synthetically formulated, and diffusion time and the number of active nodes are defined mathematically. In particular, budget efficiency is presented to describe TIMP in order that an appropriate trade‐off between diffusion time and the number of active nodes can be reached. Then, an adaptive heuristic (A‐Heuristic) scheme is proposed to dynamically determine the initial seed nodes (ie, the most influential nodes). Finally, experiments are performed, and their results verify the superior performance of the proposed scheme in terms of budget efficiency, running time, and the number of active nodes.
Neuropathy following spinal nerve injury shares features with the irritable nociceptor phenotype: A back‐translational study of oxcarbazepine
Authors: Patel Ryan , Kucharczyk Mateusz , Montagut‐Bordas Carlota , Lockwood Stevie , Dickenson Anthony H. 
Published: August 2018

AbstractBackgroundThe term ‘irritable nociceptor’ was coined to describe neuropathic patients characterized by evoked hypersensitivity and preservation of primary afferent fibres. Oxcarbazepine is largely ineffectual in an overall patient population, but has clear efficacy in a subgroup with the irritable nociceptor profile. We examine whether neuropathy in rats induced by spinal nerve injury shares overlapping pharmacological sensitivity with the irritable nociceptor phenotype using drugs that target sodium channels.MethodsIn vivo electrophysiology was performed in anaesthetized spinal nerve ligated (SNL) and sham‐operated rats to record from wide dynamic range (WDR) neurones in the ventral posterolateral thalamus (VPL) and dorsal horn.ResultsIn neuropathic rats, spontaneous activity in the VPL was substantially attenuated by spinal lidocaine, an effect that was absent in sham rats. The former measure was in part dependent on ongoing peripheral activity as intraplantar lidocaine also reduced aberrant spontaneous thalamic firing. Systemic oxcarbazepine had no effect on wind‐up of dorsal horn neurones in sham and SNL rats. However, in SNL rats, oxcarbazepine markedly inhibited punctate mechanical‐, dynamic brush‐ and cold‐evoked neuronal responses in the VPL and dorsal horn, with minimal effects on heat‐evoked responses. In addition, oxcarbazepine inhibited spontaneous activity in the VPL. Intraplantar injection of the active metabolite licarbazepine replicated the effects of systemic oxcarbazepine, supporting a peripheral locus of action.ConclusionsWe provide evidence that ongoing activity in primary afferent fibres drives spontaneous thalamic firing after spinal nerve injury and that oxcarbazepine through a peripheral mechanism exhibits modality‐selective inhibitory effects on sensory neuronal processing.SignificanceThe inhibitory effects of lidocaine and oxcarbazepine in this rat model of neuropathy resemble the clinical observations in the irritable nociceptor patient subgroup and support a mechanism‐based rationale for bench‐to‐bedside translation when screening novel drugs.
A Novel Biomass Derived Carbon Quantum Dots for Highly Sensitive and Selective Detection of Hydrazine
Authors: Sha Rinky , Jones S. Solomon , Vishnu Nandimalla , Soundiraraju Bhuvaneswari , Badhulika Sushmee 
Published: August 2018

AbstractWe report for the first time, carbon quantum dots (CQD) based highly sensitive and selective electrochemical sensor for detection of hydrazine. CQD was synthesized by pyrolysis method using a natural precursor, chia seeds. The sensing ability was studied in terms of oxygen‐rich functional groups present on the surface of CQD.
CO2 adsorption testing on fly ash derived cancrinite‐type zeolite and its amine‐functionalized derivatives
Authors: Dindi Abdallah , Viet Quang Dang , Abu‐Zahra Mohammad R.M. 
Published: August 2018

Fly ash was converted to a Cancrinite‐type zeolite and then functionalized with various amines to investigate its ability to adsorb CO2. Fly ash was first subjected to thermal‐alkaline treatment followed by hydrothermal treatment to remove unburned carbon and transform it into a cancrinite‐type zeolite before being functionalized with either 3‐aminopropyltriethoxysilane (APTES), diethanolamine (DEA), or monoethanolamine (MEA). The resulting Cancrinite and its functionalized products were characterized by various techniques to confirm the success of fly ash to Cancrinite transformation and functionalization method. Cancrinite has significant improvement in surface area (77.7 m2 g−1) in comparison with original fly ash (11.2 m2 g−1), but its CO2 adsorption is very poor, about 6.6 mg g−1. Amine functionalization caused a reduction in the surface area and porosity of the fly ash Cancrinite, however, it enhanced the CO2 adsorption significantly. While the sorbents impregnated with DEA and MEA had higher CO2 adsorption capacities (49 and 84 mg CO2/g adsorbent respectively) than the sorbent grafted with APTES (24 mg CO2/g adsorbent), the grafted sorbent was more stable over multiple adsorption–desorption cycles. This study demonstrated that fly ash‐derived Cancrinite‐type zeolite has low CO2 adsorption in spite of its high surface area, however, its CO2 adsorption can be improved by amine‐functionalization. © 2018 American Institute of Chemical Engineers Environ Prog, 38: 77–88, 2019
Distribution of health facilities in Nigeria: Implications and options for Universal Health Coverage
Authors: Makinde Olusesan Ayodeji , Sule Abayomi , Ayankogbe Olayinka , Boone David 
Published: August 2018

SummaryBackgroundNigeria is considering adopting Universal Health Coverage (UHC) as an official policy target to ensure access to quality health care services for her population without financial hardship. To facilitate discussion on the topic, the President of Nigeria convened a UHC summit in March 2014 to discuss Nigeria's options and strategies to achieve UHC. A strategy for achieving UHC requires analysis of the available infrastructure to deliver the services. We review the geographic and sectoral distribution of health facilities in Nigeria and discuss implications on the UHC strategy selected.MethodsSecondary analysis of data from the Federal Ministry of Health's facility register was performed to assess the geographic and sectoral distribution of health facilities in Nigeria. Additionally, an extensive literature review was conducted to understand UHC strategies used by various countries and the associated health facility requirements.ResultsPrimary health facilities make up 88% of health facilities in Nigeria while secondary and tertiary health facilities make up 12% and 0.25%, respectively. There are more government‐owned health facilities than privately owned health facilities (67% vs 33%). Secondary health facilities are predominantly privately owned. The ratio of public to private health facilities is much higher in the northern part of the country than in the southern part.ConclusionsThe distribution of health facilities across Nigeria is nonuniform. As such, a UHC strategy must be responsive to the variation in health facility distribution across the country. Additional investments are needed in some parts of the country to improve access to tertiary health facilities and leverage private sector capacity.
DOES FATHERS' PRENATAL MENTAL HEALTH BEAR A RELATIONSHIP TO PARENTING STRESS AT 6 MONTHS?
Authors: Skjothaug Thomas , Smith Lars , Wentzel‐Larsen Tore , Moe Vibeke 
Published: August 2018

ABSTRACTThis study aimed to explore fathers’ mental health and retrospectively reported adverse childhood experiences during pregnancy, as well as various pathways predicting self‐reported stress at 6 months’ postpartum as assessed by the Parenting Stress Index (PSI; R.R. Abidin, ). A total of 835 fathers contributed data to the study. Data collection comprised five time points during pregnancy and one at 6 months’ postpartum. The main analyses were performed using linear regression and path analyses. First, linear regression analyses showed that paternal anxiety symptoms during pregnancy predicted stress scores in the PSI child domain at 6 months (coefficient = 0.36). Second, path analyses showed that depressive symptoms during pregnancy predicted parenting stress in the child domain, mediated by spousal disharmony at 6 months’ postpartum (coefficient = 0.77). Third, adverse childhood experiences scores predicted parenting stress in the child domain by two different pathways: one mediated by anxiety symptoms in pregnancy (coefficient = 0.29) and the other by depressive symptoms in pregnancy and experienced spousal disharmony at 6 months’ postpartum (coefficient = 0.77). The findings suggest that fathers’ symptoms of anxiety and depression during pregnancy as well as adverse childhood experiences predict paternal stress and a negative perception of their children's behavior at 6 months’ postpartum.
Mass spectrometry‐based proteomic analysis reveals the interacting partners of lipin1
Authors: Wang Jian , Wang Song , Yan Chongjia , Deng Yunxia , Huang Zhiwei , Shi Ping 
Published: August 2018

AbstractAs a lipin family founding member, lipin1 exerts dual functions as a phosphatidate phosphatase enzyme and/or a co‐transcriptional regulator in lipid metabolism. In fact, it is also involved in many other cell processes. In this study, we utilized pull down assay coupled with mass spectrometry (MS) to unravel protein–protein interaction networks of lipin1 in 293T human embryonic kidney cells. Pull‐down assay on the Ni2+‐chelating column was used to isolate lipin1 complexes from 293T cells transfected with 6‐His tagged lipin1. The lipin1 complexes were analyzed on Q Exactive mass spectrometer. A total of 30 proteins were identified from label free quantitation of the MS data by Proteome Discoverer platform. The physical interaction between lipin1 and eEF1A1 was further affirmed in 293T cells transfected with 6‐His tagged lipin1 and hepatocyte SMMC7721 cells by protein immunoprecipitation and immunofluorescence microscopy. Lipin1 also interacted with HIST1H2BK, which was confirmed in SMMC7721 cells by protein immunoprecipitation. Our proteomic analysis implicated lipin1 in novel roles in various cellular processes. © 2018 IUBMB Life, 70(8):753–762, 2018
Metabolomic study for essential hypertension patients based on dried blood spot mass spectrometry approach
Authors: Bai Qianru , Peng Baohua , Wu Xue , Cao Yunfeng , Sun Xiaoyu , Hong Mo , Na Rongmei , Liu Baiting , Li Qianxiao , Li Zhu , Fang Weiyi , Zhu Ning , Zong Chengguo , Yu Qin 
Published: August 2018

AbstractHypertension is an increasingly serious public‐health challenge worldwide. The traditional blood pressure measurement method could easily and reliably detect blood pressure. However, the delayed symptom onset may influence the screening of essential hypertension (EH). In addition, EH is significantly associated to cardiovascular disease, stroke and kidney disease. Hence, it is urgent to define associated biomarkers with early diagnosis potential for EH. A dried blood spot method integrated with direct infusion mass spectrometry (MS) metabolomic analysis was applied for the detection of metabolites toward 87 EH patients and 91 healthy controls (HC). Multiple algorithms were run on training set (62 EH and 64 HC) for selecting differential metabolites as potential biomarkers. A test set (25 EH and 27 HC) was used to verify and evaluate selected potential biomarkers. A novel blood biomarker model based on Gly, Orn, C10, Orn/Cit, Phe/Tyr, and C5‐OH/C8 exhibited potential to differentiate EH patients from HC individuals, with a sensitivity of 0.8400 and a specificity of 0.8889 in test set. The metabolomic analysis of EH is beneficial to the definition of disease‐associated biomarkers and the development of new diagnostic approaches. © 2018 IUBMB Life, 70(8):777–785, 2018
College Student Writers' Use and Modification of Planning and Evaluation Strategies After a Semester of Instruction
Authors: Traga Philippakos Zoi A. , MacArthur Charles A. , Munsell Sarah 
Published: August 2018

AbstractThe purpose of this study was to investigate how students in a developmental writing course at a community college used and adapted cognitive writing strategies learned in the course. The students participated in a funded research project for the development and evaluation of a writing curriculum based on self‐regulated strategy instruction. The authors investigated students’ application of the planning and revising strategies using think‐aloud protocols. The results showed that students remembered the strategies but did not use them consistently. Also, students tended to use an outline but not always effectively. Finally, reading comprehension seemed to impact their use of revision strategies. Limitations and implications for future research are discussed.
Military and Premilitary Trauma, Attachment Orientations, and Posttraumatic Stress Disorder Severity Among Male and Female Veterans
Authors: Bannister Jenny A. , Lopez Frederick G. , Menefee Deleene S. , Norton Peter J. , Wanner Jill 
Published: August 2018

AbstractSamples in prior studies examining attachment theory in the military have been predominantly composed of male combat veterans. Given the rates of sexual trauma among female veterans and differences in the association between attachment and posttraumatic stress disorder (PTSD) severity for sexual trauma survivors, it was necessary to consider the attachment characteristics of veterans within a mixed‐sex sample. Participants were a mixed‐sex veteran sample seeking inpatient trauma‐related treatment (N = 469). Using independent samples t tests, we examined sex differences in attachment. Consistent with our hypothesis, women reported a higher level of attachment anxiety than did men, t(351) = −2.12, p = .034. Women also reported a higher level of attachment avoidance, t(351) = −2.44, p = .015. Using hierarchical regression, we examined the contribution of attachment anxiety and avoidance to PTSD severity, partialing out variance accounted for by demographic variables and traumatic experiences. Consistent with our hypotheses, attachment avoidance predicted PTSD severity on the Clinician‐Administered PTSD Scale for DSM‐IV (CAPS), β = .20, p < .001, and the PTSD Checklist–Civilian Version (PCL‐C), β = .18, p < .001. Attachment anxiety did not predict CAPS severity but did predict PCL‐C severity, β = .11, p = .020. These results suggest the association between attachment avoidance and PTSD is not exclusive to combat trauma and may apply more generally to the larger veteran population. Higher levels of attachment anxiety and avoidance among female veterans potentially implicate the presence of greater attachment fearfulness among this particular subpopulation of veterans.
Detection of Second Primary Malignancies of the Esophagus and Hypophraynx in Oral Squamous Cell Carcinoma Patients
Authors: Matsui Toshihiro , Okada Takuya , Kawada Kenro , Okuda Masahumi , Ogo Taichi , Nakajima Yutaka , Kume Yuichiro , Ryotokuji Tairo , Hoshino Akihiro , Tokairin Yutaka , Michi Yasuyuki , Harada Hiroyuki , Nakajima Yasuaki , Kawano Tatsuyuki 
Published: August 2018

ObjectiveTo assess the usefulness of modified esophagogastroduodenoscopy (EGD) for the detection of second primary malignancies of the esophagus or hypopharynx in patients with oral squamous cell carcinoma and determine the association between the oral lesion subsite and esophageal or hypopharyngeal lesion occurrence.Study DesignRetrospective review.MethodsIn total, 166 patients with oral squamous cell carcinoma without any established symptoms of esophageal or hypopharyngeal squamous cell carcinoma underwent modified EGD based on the Valsalva maneuver and U‐turn method, image‐enhanced endoscopy, and chromoendoscopy using Lugol's iodine for diagnosis. All suspected lesions were biopsied to determine the clinical stages and duplication rates. Odds ratios for the occurrence of duplicate lesions according to the oral lesion subsite were determined.ResultsIn total, 37 esophageal and 16 hypopharyngeal lesions were detected. According to the Union for International Cancer Control/American Joint Committee on Cancer classification (2009), 75.7% and 5.4% esophageal lesions were classified as stage IA and IB, respectively, and 50% and 18.8% hypopharyngeal lesions as stage II and stage I, respectively. Approximately 59.1% and 50% esophageal and hypopharyngeal lesions, respectively, were successfully treated by endoscopic resection. Oral lesions involving the floor of the mouth were more frequently accompanied by second primary malignancies of the esophagus or hypopharynx.ConclusionsModified EGD is an effective noninvasive technique for early diagnosis and treatment of second primary malignancies of the esophagus and hypopharynx in patients with oral squamous cell carcinoma. In particular, patients with floor of the mouth lesions need close monitoring for hypopharyngeal and esophageal lesions.Level of Evidence3b.
Stimuli‐Responsive Ruthenium‐Containing Polymers
Authors: Zhou Hongwei , Chen Mingsen , Liu Yuanli , Wu Si 
Published: August 2018

AbstractRuthenium‐containing polymers (RCPs) are a type of functional metallopolymer. Stimuli‐responsive RCPs in which the responsive behaviors derive from the structure variation of Ru complexes are reviewed in this Feature Article, with particular focus on redox responsive RCPs and photoresponsive RCPs. On the basis of the recent progress, the response principle, syntheses, structures, properties, applications, and remaining challenges of such stimuli‐responsive RCPs are discussed.
High‐Performance Polymer Solar Cells Achieved by Introducing Side‐Chain Heteroatom on Small‐Molecule Electron Acceptor
Authors: Zhang Jianyun , Liu Feng , Chen Shanshan , Yang Changduk , Zhu Xiaozhang , Zhu Daoben 
Published: August 2018

AbstractSide chains of photovoltaic materials play an important role in determining charge transport property, film morphology, and the corresponding device performance. In this work, two new acceptor materials, ATT‐6 and ATT‐7 with different side chains, m‐hexylphenyl and m‐hexyloxyphenyl on the indacenodithiophene, are designed and synthesized for applications in non‐fullerene polymer solar cells. ATT‐7 shows a higher absorption coefficient, increased crystallinity, and improved electron mobility in comparison with ATT‐6. Using wide‐bandgap polymer poly[(2,6‐(4,8‐bis(5‐(2‐ethylhexyl)thiophen‐2‐yl)‐benzo[1,2‐b:4,5‐b′]dithiophene))‐alt‐(5,5‐(1′,3′‐di‐2‐thienyl‐5′,7′‐bis(2‐ethylhexyl)benzo[1′,2′‐c:4′,5′‐c′]dithiophene‐4,8‐dione)] (PBDB‐T) as donor, optimized devices based on PBDB‐T:ATT‐7 and PBDB‐T:ATT‐6 delivers power conversion efficiencies of 10.30% and 8.39%, respectively. The higher performance of ATT‐7‐based device can be attributed to efficient exciton dissociation, reduced bimolecular recombination, and enhanced and balanced charge carrier mobilities. These results indicate that side‐chain modification is an easy but efficient way in the design of high‐performance non‐fullerene acceptors.
One‐Pot Synthesis of Block Copolymers by a Combination of Living Cationic and Controlled Radical Polymerization
Authors: Trützschler Anne‐Kristin , Leiske Meike N. , Strumpf Maria , Brendel Johannes C. , Schubert Ulrich S. 
Published: August 2018

AbstractThe reversible addition–fragmentation chain‐transfer (RAFT) process represents a sophisticated polymerization technique for the preparation of tailored and well‐defined polymers from acrylates, acrylamides, and (meth)acrylates. The direct switching from other methods, such as cationic polymerizations, without the need for tedious functionalization and purification steps remains challenging. Within this study, it is demonstrated that poly(2‐oxazoline) (P(Ox)) macro chain‐transfer agents (macro‐CTAs) can be prepared through the quenching of the cationic ring‐opening polymerization with a carbonotrithioate salt. The end‐functionalization of the P(Ox)s is observed to be almost quantitative and the macro‐CTAs could be directly used for RAFT polymerization without further purification. This one‐pot procedure could be extended to a variety of (multi)block copolymers consisting of different 2‐oxazolines and acrylates with good‐to‐excellent control. Kinetic studies revealed the controlled polymerization of block copolymers, which are further accessible for α‐ and ω‐end‐functionalization. The simplicity and versatility of the approach promise a straightforward access to block copolymers from cationic and controlled radical polymerizations.
Block Copolymers by Mechanistic Transformation from PROAD to Iniferter Process
Authors: Ciftci Mustafa , Yagci Yusuf 
Published: August 2018

AbstractA facile strategy for synthesizing block copolymers by the combination of two different living polymerization techniques, namely, photoinduced radical oxidation/addition/deactivation (PROAD) and iniferter processes is described. In the first step, PROAD polymerization of isobutyl vinyl ether using bromotriphenylmethane, dimanganese decacarbonyl (Mn2(CO)10), and diphenyliodonium bromide (Ph2I+Br−) is carried out to yield polymers with triphenylmethyl (trityl) end groups. These prepolymers are used as macroiniferters in thermally induced free radical polymerization of vinyl monomers such as methyl methacrylate, tert‐butyl acrylate, and styrene, resulting in the formation of corresponding block copolymers free from homopolymers. The precursor polymer and final block copolymers are characterized by 1H NMR, FT‐IR, GPC, and DSC analyses.
Hyperbranched Polymers Formed Through Self‐Condensing Vinyl Polymerization in a Continuous Stirred‐Tank Reactor (CSTR): 1. Molecular Weight Distribution
Authors: Tobita Hidetaka 
Published: August 2018

AbstractA new Monte Carlo simulation algorithm, based on the random sampling technique, is proposed for the self‐condensing vinyl polymerization conducted in a continuous stirred‐tank reactor. In order to highlight the most fundamental aspects of the reaction system, the kinetic rate constants are assumed to be constant, and the size and structure dependence is neglected. With this ideal model, the high molecular weight (MW) tail of the weight fraction distribution W(P) is shown to follow the power law, W(P) ∝ P
−α. The power exponent is represented by α = 1/(ηξ) for ξ < 1/(2η), where ξ and η are defined in the text. For ξ ≥ 1/(2η), the weight‐average MW cannot reach the steady state because of the power exponent with α ≤ 2.