bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robot for health data acquisition among older adults: a pilot randomised controlled cross-over trial
Authors: Boumans Roel , van Meulen Fokke , Hindriks Koen , Neerincx Mark , Olde Rikkert Marcel G M 
Published: March 2019

Background /ObjectivesHealthcare professionals (HCP) are confronted with an increased demand for assessments of important health status measures, such as patient-reported outcome measurements (PROM), and the time this requires. The aim of this study was to investigate the effectiveness and acceptability of using an HCP robot assistant, and to test the hypothesis that a robot can autonomously acquire PROM data from older adults.DesignA pilot randomised controlled cross-over study where a social robot and a nurse administered three PROM questionnaires with a total of 52 questions.SettingA clinical outpatient setting with community-dwelling older adults.ParticipantsForty-two community-dwelling older adults (mean age: 77.1 years, SD: 5.7 years, 45% female).MeasurementsThe primary outcome was the task time required for robot–patient and nurse–patient interactions. Secondary outcomes were the similarity of the data and the percentage of robot interactions completed autonomously. The questionnaires resulted in two values (robot and nurse) for three indexes of frailty, well-being and resilience. The data similarity was determined by comparing these index values using Bland-Altman plots, Cohen’s kappa (κ) and intraclass correlation coefficients (ICC). Acceptability was assessed using questionnaires.ResultsThe mean robot interview duration was 16.57 min (SD=1.53 min), which was not significantly longer than the nurse interviews (14.92 min, SD=8.47 min; p=0.19). The three Bland-Altman plots showed moderate to substantial agreement between the frailty, well-being and resilience scores (κ=0.61, 0.50 and 0.45, and ICC=0.79, 0.86 and 0.66, respectively). The robot autonomously completed 39 of 42 interviews (92.8%).ConclusionSocial robots may effectively and acceptably assist HCPs by interviewing older adults.
Conservative treatment of anterior chronic exertional compartment syndrome in the military, with a mid-term follow-up
Authors: Zimmermann Wes O , Hutchinson Mark Robert , Van den Berg Ruud , Hoencamp Rigo , Backx Frank J G , Bakker Eric W P 
Published: March 2019

ObjectivesTo assess the outcome of conservative treatment for chronic exertional compartment syndrome (CECS) as it relates to the reduction in surgical fasciotomy and return to active duty in a military population.MethodsHistoric cohort. From 2015 to 2018, 75 surgically eligible patients with pressure-positive anterior CECS (Group 1), or with positive pressures and associated medial tibial stress syndrome (Group 2), underwent a conservative treatment programme emphasising gait retraining of running and marching. Treatment success was defined as return to duty, without surgery. Fifty patients from 2015 to 2017 were surveyed to assess mid-term outcomes.ResultsThe average duration of conservative treatment was 144.9 (±59.6) days. Initially, 65% (49/75) were able to return to duty; 28% (21/75) were referred for surgery and 7% (5/75) left the armed forces. There was no difference in outcomes between Group 1 and Group 2. Survey response rate, on average after 742 days (SD 267, range 381–1256), was 84% (42/50); 57% (24/42) had continued duty, without surgery; of them, 43% were at the same military specialty, 57% in a physically less demanding job.ConclusionA conservative treatment programme for anterior CECS was able to return 65 % of patients to active duty, without surgery. At 2 years, the success rate decreased slightly, but remained positive at 57%. In this high-risk group, initiating a conservative treatment protocol with an emphasis on gait retraining can significantly reduce the need for surgical fasciotomy. For those that fail conservative treatment, surgical release may still be indicated.
Machine Translation Evaluation: Unveiling the Role of Dense Sentence Vector Embedding for Morphologically Rich Language
Authors: Tripathi Samiksha , Kansal Vineet 
Published: March 2019

Machine Translation (MT) evaluation metrics like BiLingual Evaluation Understudy (BLEU) and Metric for Evaluation of Translation with Explicit Ordering (METEOR) are known to have poor performance for word-order and morphologically rich languages. Application of linguistic knowledge to evaluate MTs for morphologically rich language like Hindi as a target language, is shown to be more effective and accurate [S. Tripathi and V. Kansal, Using linguistic knowledge for machine translation evaluation with Hindi as a target language, Comput. Sist.21(4) (2017) 717–724]. Leveraging the recent progress made in the domain of word vector and sentence vector embedding [T. Mikolov and J. Dean, Distributed representations of words and phrases and their compositionality, Adv. Neural Inf. Process. Syst. 2 (2013) 3111–3119], authors have trained a large corpus of pre-processed Hindi text ([Formula: see text] million tokens) for obtaining the word vectors and sentence vector embedding for Hindi. The training has been performed on high end system configuration utilizing Google Cloud platform resources. This sentence vector embedding is further used to corroborate the findings through linguistic knowledge in evaluation metric. For morphologically rich language as target, evaluation metric of MT systems is considered as an optimal solution. In this paper, authors have demonstrated that MT evaluation using sentence embedding-based approach closely mirrors linguistic evaluation technique. The relevant codes used to generate the vector embedding for Hindi have been uploaded on code sharing platform Github. a
Productivity Assessment Based on Jump Diffusion Model Considering the Effort Management for OSS Project
Authors: Tamura Yoshinobu , Sone Hironobu , Yamada Shigeru 
Published: March 2019

Various open source software (OSS) projects are in action around the world. Many OSS are developed and maintained under these OSS projects. Considering the characteristics of OSS, the operation performance of OSS development will take an irregular fluctuation in the long term of operation, because several developers and many users are closely related to the maintenance of OSS. This paper focuses on the irregular fluctuation of the operation performance of OSS. We apply the jump diffusion process model to the noisy cases in the operation of OSS. In particular, the maintenance effort is estimated by the stochastic differential equation model in terms of OSS project management. Moreover, we discuss the method of maintenance effort management based on jump diffusion process model considering the irregular fluctuation of performance for OSS projects. In particular, we propose the method of productivity assessment based on the proposed jump diffusion models. Thereby, it is helpful for the OSS development managers to understand the effort status of OSS from the standpoint of OSS project management. Also, we analyze actual data to show numerical examples of the proposed method considering the characteristics of OSS projects.
Optimal Policy of Window Flow Control Based on Packet Transmission Interval with Explicit Congestion Notification
Authors: Kimura Mitsutaka , Imaizumi Mitsuhiro , Nakagawa Toshio 
Published: March 2019

This paper discusses a reliability problem of window flow control scheme with Explicit Congestion Notification (ECN) in the communication system, which is an essential issue in the long-distance transmission such as cloud computing. For example, there is a problem of reduction in transmission efficiency caused by a packet loss from network congestion. In order to solve the problem, recently, High-performance and Flexible Protocol (HpFP) has been proposed and performed a verification of effectiveness by simulation. 6 HpFP provides efficient packet communication by changing a packet transmission interval [T. Murata, T. Mizuhara, A. Takagi, K. Fukushima, K. Yamamoto, Y. Nagaya, K. Muranaga and E. Kimura, HpFP: A new protocol for LFNs with packet-loss based on UDP: A basic concept and detailed design of the protocol, IEICE Technical Report 115(484) IN2015-109, pp. 7–12 (2016)]. We have discussed the reliability model of a window flow control scheme based on a packet transmission interval. 7 We have proposed the model which judges the occurrence of congestion in a network by the number of retransmission [M. Kimura, M. Imaizumi and T. Nakagawa, Reliability modelling of window flow control scheme for a communication system based on packet transmission interval, in Proc. 23rd ISSAT Int. Conf. Reliability and Quality in Design (2017), pp. 171–175]. On the other hand, ECN mechanism for the detection of incipient congestion has been already proposed. ECN mechanism is efficient for the window flow control scheme because ECN bit is set in the packet header as an indication of congestion and is avoided unnecessary packet drops. We consider a stochastic model of a window flow control scheme based on a packet transmission interval with ECN. If ECN bit has been set during connection, a packet transmission interval is prolonged. We derive the mean time until packet transmissions succeed, and analytically discuss an optimal policy to maximize the amount of packets per unit of time until the transmission succeeds.
Discharge properties of morphologically identified vestibular neurons recorded during horizontal eye movements in the goldfish
Authors: Pastor A. M. , Calvo P. M. , de la Cruz R. R. , Baker R. , Straka H. 
Published: March 2019

Computational capability and connectivity are key elements for understanding how central vestibular neurons contribute to gaze-stabilizing eye movements during self-motion. In the well-characterized and segmentally distributed hindbrain oculomotor network of goldfish, we determined afferent and efferent connections along with discharge patterns of descending octaval nucleus (DO) neurons during different eye motions. Based on activity correlated with horizontal eye and head movements, DO neurons were categorized into two complementary groups that either increased discharge during both contraversive (type II) eye (e) and ipsiversive (type I) head (h) movements (eIIhI) or vice versa (eIhII). Matching time courses of slow-phase eye velocity and corresponding firing rates during prolonged visual and head rotation suggested direct causality in generating extraocular motor commands. The axons of the dominant eIIhI subgroup projected either ipsi- or contralaterally and terminated in the abducens nucleus, Area II, and Area I with additional recurrent collaterals of ipsilaterally projecting neurons within the parent nucleus. Distinct feedforward commissural pathways between bilateral DO neurons likely contribute to the generation of eye velocity signals in eIhII cells. The shared contribution of DO and Area II neurons to eye velocity storage likely represents an ancestral condition in goldfish that is clearly at variance with the task separation between mammalian medial vestibular and prepositus hypoglossi neurons. This difference in signal processing between fish and mammals might correlate with a larger repertoire of visuo-vestibular-driven eye movements in the latter species that potentially required a shift in sensitivity and connectivity within the hindbrain-cerebello-oculomotor network. NEW & NOTEWORTHY We describe the structure and function of neurons within the goldfish descending octaval nucleus. Our findings indicate that eye and head velocity signals are processed by vestibular and Area II velocity storage integrator circuitries whereas the velocity-to-position Area I neural integrator generates eye position solely. This ancestral condition differs from that of mammals, in which vestibular neurons generally lack eye position signals that are processed and stored within the nucleus prepositus hypoglossi.
Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells
Authors: Di Lorenzo Biagio , Simões André E. , Caiado Francisco , Tieppo Paola , Correia Daniel V. , Carvalho Tânia , da Silva Maria Gomes , Déchanet-Merville Julie , Schumacher Ton N. , Prinz Immo , Norell Haakan , Ravens Sarina , Vermijlen David , Silva-Santos Bruno 
Published: March 2019

Abstract
Acute myeloid leukemia (AML) remains a clinical challenge due to frequent chemotherapy resistance and deadly relapses. We are exploring the immunotherapeutic potential of peripheral blood Vδ1+ T cells, which associate with improved long-term survival of stem-cell transplant recipients but have not yet been applied as adoptive cell therapy. Using our clinical-grade protocol for expansion and differentiation of “Delta One T” (DOT) cells, we found DOT cells to be highly cytotoxic against AML primary samples and cell lines, including cells selected for resistance to standard chemotherapy. Unlike chemotherapy, DOT-cell targeting did not select for outgrowth of specific AML lineages, suggesting a broad recognition domain, an outcome that was consistent with the polyclonality of the DOT-cell T-cell receptor (TCR) repertoire. However, AML reactivity was only slightly impaired upon Vδ1+ TCR antibody blockade, whereas it was strongly dependent on expression of the NKp30 ligand, B7-H6. In contrast, DOT cells did not show reactivity against normal leukocytes, including CD33+ or CD123+ myeloid cells. Adoptive transfer of DOT cells in vivo reduced AML load in the blood and target organs of multiple human AML xenograft models and significantly prolonged host survival without detectable toxicity, thus providing proof-of-concept for DOT-cell application in AML treatment.
Machine Learning–Based Model for Prediction of Outcomes in Acute Stroke
Authors: Heo JoonNyung , Yoon Jihoon G. , Park Hyungjong , Kim Young Dae , Nam Hyo Suk , Heo Ji Hoe 
Published: March 2019

Background and Purpose—
The prediction of long-term outcomes in ischemic stroke patients may be useful in treatment decisions. Machine learning techniques are being increasingly adapted for use in the medical field because of their high accuracy. This study investigated the applicability of machine learning techniques to predict long-term outcomes in ischemic stroke patients.

Methods—
This was a retrospective study using a prospective cohort that enrolled patients with acute ischemic stroke. Favorable outcome was defined as modified Rankin Scale score 0, 1, or 2 at 3 months. We developed 3 machine learning models (deep neural network, random forest, and logistic regression) and compared their predictability. To evaluate the accuracy of the machine learning models, we also compared them to the Acute Stroke Registry and Analysis of Lausanne (ASTRAL) score.

Results—

A total of 2604 patients were included in this study, and 2043 (78%) of them had favorable outcomes. The area under the curve for the deep neural network model was significantly higher than that of the ASTRAL score (0.888 versus 0.839;
P
<0.001), while the areas under the curves of the random forest (0.857;
P
=0.136) and logistic regression (0.849;
P
=0.413) models were not significantly higher than that of the ASTRAL score. Using only the 6 variables that are used for the ASTRAL score, the performance of the machine learning models did not significantly differ from that of the ASTRAL score.

Conclusions—
Machine learning algorithms, particularly the deep neural network, can improve the prediction of long-term outcomes in ischemic stroke patients.
Validation of new genus the Miniagraecia (Orthoptera: Tettigoniidae)
Authors: RENTZ DCF , SU YOU NING , UESHIMA N. 
Published: March 2019

It has been pointed out that there is an error in our recent paper (Rentz et al., 2012). On p. 24 we designated Miniagraecia viridis Rentz, Su, Ueshima sp. nov. as the type species of the new genus Miniagraecia. However there is no such species. There was a manuscript change in the name of the species and we did not catch it in the type species designation. Miniagraecia is therefore a nomen nudum. Miniagraecia viridis is not a nominal species and Miniagraecia does not now have a fixed type species (International Code of Zoological Nomenclature, Article 67.1).
Taxonomic corrections of certain verified non-indigenous reptiles from Florida reported by Krysko et al. (2011)
Authors: KRYSKO KENNETH L. , SOMMA LOUIS A. , ROCHFORD MICHAEL R. , GILLETTE CHRISTOPHER R. , ENGE KEVIN M. , CUEVA DANIEL 
Published: March 2019

In a recent issue of Zootaxa, Krysko et al. (2011) compiled and evaluated vouchers (i.e., specimens and photographs), and confirmed three intercepted and 137 introduced species of non-indigenous amphibians and reptiles in Florida from 1863 through 2010. Trying to improve upon previous methodologies of reporting new non-indigenous species, we stressed the importance of providing all known data along with vouchers to help keep numbers of species consistent, accurately identify species, document when and where a particular species is found, and identify the invasion pathway and current invasion stage of each species. High resolution digital images of each of the 83 newly confirmed taxa were registered in MorphoBank (www.morphobank.org; project number p536). Physical voucher specimens are always preferred over photographs, as it can be quite difficult to accurately identify species that are morphologically similar or cryptic, especially in species that we are unfamiliar with or may originate in different countries. In this paper we attempt to correct the species names of four taxa as well as the family and authority names attributed to one species.
New synonymy for a species of mealybug in the genus Pseudococcus (Hemiptera: Pseudococcidae) that occurs on fruit trees in Chile
Authors: GONZÁLEZ ROBERTO H. , PRADO ERNESTO 
Published: March 2019

In July of 2011, we each became aware that we were studying the same Chilean mealybug species. The research by González (2011) emphasized the biology, economic importance, and control of the species on fruit, and described it as the new species Pseudococcus rubigena González. The research by Prado in Correa et al. (2011) provided a detailed description using molecular and morphological data and described the new species as P. meridionalis Prado. Based on the Principle of Priority (Article 23) in the International Code of Zoological Nomenclature (1999), one of these names must have precedence. Unfortunately, both papers were published at approximately the same time. The date of publication of the Correa et al. paper is clearly marked as June 22, 2011. The exact date of publication of the González book was not clear because it did not give a specific date, only 2011. To establish the exact date, a certificate of publication was requested from the publisher (Imprenta Italiana Ltda.) by González. In a letter dated November 23, 2011, Nelson Cannoni M., Gerente General, Impreta Italiana indicated “ULTIMO DESPACHO DE EJEMPLARES: 30 de junio de 2011.” This is considered the date of publication for the name P. rubigena which was predated by P. meridionalis by just nine days. Therefore the following synonymy is proposed.
Tennyson’s Poems
Authors: Winnick R. H. 
Published: March 2019

In Tennyson’s Poems: New Textual Parallels, R. H. Winnick identifies more than a thousand previously unknown instances in which Tennyson phrases of two or three to as many as several words are similar or identical to those occurring in prior works by other hands—discoveries aided by the proliferation of digitized texts and the related development of powerful search tools over the three decades since the most recent major edition of Tennyson’s poems was published.
Each of these instances may be deemed an allusion (meant to be recognized as such and pointing, for definable purposes, to a particular antecedent text), an echo (conscious or not, deliberate or not, meant to be noticed or not, meaningful or not), or merely accidental. Unless accidental, Winnick writes, these new textual parallels significantly expand our knowledge both of Tennyson’s reading and of his thematic intentions and artistic technique. Coupled with the thousand-plus textual parallels previously reported by Christopher Ricks and other scholars, he says, they suggest that a fundamental and lifelong aspect of Tennyson’s art was his habit of echoing any work, ancient or modern, which had the potential to enhance the resonance or deepen the meaning of his poems.
The new textual parallels Winnick has identified point most often to the King James Bible and to such canonical authors as Shakespeare, Milton, Dryden, Pope, Thomson, Cowper, Shelley, Byron, and Wordsworth. But they also point to many authors rarely if ever previously cited in Tennyson editions and studies, including Michael Drayton, Richard Blackmore, Isaac Watts, Erasmus Darwin, John Ogilvie, Anna Lætitia Barbauld, Letitia Elizabeth Landon, John Wilson, and—with surprising frequency—Felicia Hemans.
Tennyson’s Poems: New Textual Parallels is thus a major new resource for Tennyson scholars and students, an indispensable adjunct to the 1987 edition of Tennyson’s complete poems edited by Christopher Ricks.
MRI ultrasound fusion biopsy in prostate cancer detection: Are randomized clinical trials reproducible in everyday clinical practice?
Authors: Cattarino Susanna , Forte Valerio , Salciccia Stefano , Drudi Francesco Maria , Cantisani Valerio , Sciarra Alessandro , Fasulo Andrea , Ciccariello Mauro 
Published: March 2019

Introduction: The aim of this study was to evaluate the performance of multiparametric magnetic resonance imaging (mpMRI)–ultrasound (US) fusion-targeted biopsies (TB) in men with primary and repeated biopsies comparing the cancer detection rate (CDR) of random biopsies (RB) + TB versus only TB. Methods: The present study is a real-life study on patients with primary and prior negative prostate biopsies with suspicious PCa. A total of 130 men with prostate-specific antigen (PSA) value >2.5 ng/dL and/or abnormal digital rectal examination (DRE) were included in the study and subjected to mpMRI. Patients with >2 previous biopsies and/or with ⩾3 suspected lesions on MRI and/or prostate imaging-reporting and data system (PIRADS) value ⩾4 (n:30 pts) were subjected only to TB on the areas indicated by mpMRI. All the other patients (n:70 pts) were subjected to standard random laterally directed 10-core plus TB on the areas indicated by mpMRI. Results: The overall CDR was 53% (53/100). In relation to PIRADS score, the overall CDR was 0, 40% (12/30), 56.83% (29/51), and 84% (11/13) for PIRADS 2, 3, 4, and 5, respectively. According to biopsy modality, CDR for RB + TB was 50% (35/70) and CDR for TB was 60% (18/30) with a p-value of 0.3632. Discussion: MRI–US fusion biopsy is associated with a high CDR of clinically significant PCa (csPCa). MRI–US fusion biopsy could be a reasonable approach in patients with previous negative biopsy and high PIRADS score on MRI, to ensure a high CDR of csPCa and to reduce the diagnosis of clinically insignificant tumors.