bluuebunny/crossref_metadata_2025_split huggingface dataset:
Non-spectrality of self-affine measures on the three-dimensional Sierpinski gasket
Authors: Lu Zheng-Yi , Dong Xin-Han , Zhang Peng-Fei 
Published: July 2019

Abstract
Let

μ

M
,
D

{\mu_{M,D}}

be a self-affine measure generated by an expanding diagonal matrix

M
∈

M
3

⁢

(
ℝ
)

{M\in M_{3}(\mathbb{R})}

with entries

ρ
1

,

ρ
2

,

ρ
3

{\rho_{1},\rho_{2},\rho_{3}}

and the digit set

D
=

{

(
0
,
0
,
0
)

t

,

(
1
,
0
,
0
)

t

,

(
0
,
1
,
0
)

t

,

(
0
,
0
,
1
)

t

}

{D=\{(0,0,0)^{t},(1,0,0)^{t},(0,1,0)^{t},(0,0,1)^{t}\}}

.
In this paper, we prove that for any

ρ
1

,

ρ
2

,

ρ
3

∈

(
1
,
∞
)

{\rho_{1},\rho_{2},\rho_{3}\in(1,\infty)}

, if

ρ
1

,

ρ
2

,

ρ
3

∈

{

±

x

1
r

:

x
∈

ℚ
+

,

r
∈

ℤ
+

}

{\rho_{1},\rho_{2},\rho_{3}\in\{\pm x^{\frac{1}{r}}:x\in\mathbb{Q}^{+},r\in%
\mathbb{Z}^{+}\}}

, then

L
2

⁢

(

μ

M
,
D

)

{L^{2}(\mu_{M,D})}

contains an infinite orthogonal set of exponential functions if and only if there exist two numbers of

ρ
1

,

ρ
2

,

ρ
3

{\rho_{1},\rho_{2},\rho_{3}}

that are in the set

{

±

(

p
q

)

1
r

:

p
∈

2
⁢

ℤ
+

,

q
∈

2
⁢

ℤ
+

-

1
⁢
and
⁢
r

∈

ℤ
+

}

{\{\pm(\frac{p}{q})^{\frac{1}{r}}:p\in 2\mathbb{Z}^{+},q\in 2\mathbb{Z}^{+}-1%
\text{ and }r\in\mathbb{Z}^{+}\}}

.
In particular, if

ρ
1

,

ρ
2

,

ρ
3

∈

{

p
q

:

p
,
q

∈

2
⁢
ℤ

+
1

}

{\rho_{1},\rho_{2},\rho_{3}\in\{\frac{p}{q}:p,q\in 2\mathbb{Z}+1\}}

, then there exist at most 4 mutually orthogonal exponential functions in

L
2

⁢

(

μ

M
,
D

)

{L^{2}(\mu_{M,D})}

, and the number 4 is the best possible.
Synthesis of vitamin E succinate catalyzed by nano-SiO2 immobilized DMAP derivative in mixed solvent system
Authors: Chen Dan , Li Binglin , Li Bin , Zhang Xiaoli , Wei Longhui , Zheng Wenwen 
Published: July 2019

Abstract
Catalytic efficiency in synthesis of vitamin E succinate was dramatically increased via the preparation of robust catalyst and the improvement of reaction system. 4-dimethylaminopyridine (DMAP) was covalently immobilized on nano-SiO2 to avoid the catalyst contamination of the product and permit the easy recycling of DMAP. Then, a hexane-acetone mixed solvent system was firstly introduced to replace the traditional single-solvent system, which was employed to improve the activity of immobilized DMAP derivative and the substrate solubility of the reaction system. The highest vitamin E succinate yield of 94% was achieved. In addition, the recyclability and stability of the immobilized DMAP derivative was excellent, the yield of vitamin E succinate had no obvious loss and remained 90% after recycling 20 times. The excellent results make this technology be a promising candidate for the industrial production of vitamin E succinate.
Biofabrication of highly pure copper oxide nanoparticles using wheat seed extract and their catalytic activity: A mechanistic approach
Authors: Buazar Foad , Sweidi Sajjad , Badri Mohammad , Kroushawi Feisal 
Published: July 2019

Abstract
A facile novel green methodology is presented for the synthesis of highly stable and well-dispersed copper oxide nanoparticles using aqueous wheat seed extract. Under optimal reaction conditions, the wheat seed extract-derived electron-rich biomolecules were functioned as a reducing and capping/ stabilizing agent. The ultraviolet-visible absorption peak at 300 nm was confirmed the formation of copper oxide nanoparticles. Fourier-transform infrared spectroscopy analysis determined Cu–O bonds in nanosample, indicating the active role of functional groups in the wheat seed extract in bio-reduction of Cu cations. X-ray diffraction pattern results demonstrated the monoclinic structure of highly pure biosynthesized copper oxide nanoparticles with a crystallite size of 20.76 nm. The stability of copper oxide nanoparticles was confirmed after 3 months’ storage of product with no sedimentation or suspension. Transmission electron microscopy results showed the spherical shape of nano-particle with an average size of 22 ± 1.5 nm. X-ray photo-electron spectroscopy analyses revealed only copper and oxygen elements in the sample, confirming the purity of copper oxide nanoparticles. Bio-assisted copper oxide nanoparticles demonstrated significant catalytic efficiency and reusability toward 4-nitrophenol removal by an average of 97.6% from aqueous solutions after successive 5 days’ exposure to UV irradiation.
Lie Symmetries, One-Dimensional Optimal System and Group Invariant Solutions for the Ripa System
Authors: Kumar Pradhan Pabitra , Pandey Manoj 
Published: July 2019

Abstract
A complete symmetry group classification for the system of shallow water equations with the horizontal temperature gradient, also known as Ripa system, is presented. A rigorous and systematic procedure based on the general invariants of the adjoint representation is used to construct the one-dimensional optimal system of the Lie algebra. The complete inequivalence class of the group invariant solutions are obtained by using the one-dimensional optimal system. One such solution of the Ripa system is used to study the evolutionary behaviour of the discontinuity wave.
Methods for the Study of Physical and Chemical Stability and Container-Content Interactions: Report of a GERPAC Workshop
Authors: Sautou Valérie , Lagarce Frédéric 
Published: July 2019

Abstract
This opinion paper describes the discussions of the attendees of the last GERPAC European conference workshop on the question of chemical stability and container-content interactions. Pharmacists discussed the steps to implement to carry out those studies that are particulary important to asses the quality of the compounded preparations in hospital pharmacies.
Indentation Creep Response and Rupture Mechanisms in GLARE: Experimental and Statistical Evaluation
Authors: Thirukumaran M. , Winowlin Jappes J. T. , Siva I. , Anand Kumar S. , Amico Sandro C. 
Published: July 2019

Abstract
Fiber metal laminates (FMLs) are structural materials that play a vital role in the aviation sector, in which they are exposed to cyclic long-term loading. This article investigates creep response and rupture mechanisms of glass laminate aluminum reinforced epoxy (GLARE) FMLs based on microindentation creep testing. Specimens were manufactured by compression molding, and experiments were conducted under different test parameters, namely, aluminum surface treatment (in terms of surface roughness), creep chamber temperature, indentation load, and run time. In addition, rupture mechanisms were analyzed using scanning electron microscopy. The individual interaction of control parameters on creep strain and mass loss response was studied using Taguchi method. Among the studied factors, specimen condition and creep chamber temperature predominantly control creep rupture, whereas load and time were less important, as confirmed by statistical predictions using linear regression.
The Statistical Scale Effect as a Source of Positive Genetic Correlation Between Mean and Variability: A Simulation Study
Authors: Tatliyer Adile , Cervantes Isabel , Formoso-Rafferty Nora , Gutiérrez Juan Pablo 
Published: July 2019

AbstractThe selection objective for animal production is the highest income with the lowest production cost, while ensuring the highest animal welfare. A selection experiment for environmental variability of birth weight in mice showed a correlated response in the mean after 20 generations starting from a crossed panmictic population. The relationship between the birth weight and its environmental variability explained the correlated response. The scale effect represents a potential cause of this correlation. The relationship between the mean and the variability implies: the higher the mean, the higher the variability. The study was to quantify by simulation the genetic correlation between a trait and its environmental variability. This can be attributable to the scale effect in a range of coefficients of variation and heritabilities between 0.05 and 0.50. The resulting genetic correlation ranged from 0.1335 to 0.7021 being the highest for the highest heritability and the lowest CV. The scale effect for a trait with heritability between 0.25 and 0.35 and CV between 0.15 and 0.25 generated a genetic correlation between 0.43 and 0.57. The genetic coefficient of variation (GCV) affecting residual variability was modulated by the strength reducing the impact of the scale effect. GCV ranged from 0.0050 to 1.4984. The strength of the scale effect might be in the range between 0 and 1. The scale effect would explain many reported genetic correlation and the additive genetic variance for the variability. This is relevant when increasing the mean of a trait jointly with the reduction of its variability.
Spread of a surface plume in unsteady and steady flows
Authors: Anwar H. O. 
Published: July 2019

A series of laboratory measurements was undertaken in unsteady and steady flows to determine the spread and mixing of surface plumes, emitting from a heat source without momentum. Instantaneous temperatures were measured in the vertical and lateral directions at various downstream sections; similar measurements were made when the ambient currents were steady. The mean temperature profiles in the lateral and vertical directions were of the Gaussian form in steady and unsteady flows. The outstanding results were those obtained when the flow was unsteady; the plume dilution, the plume spread and the turbulence intensity of temperature fluctuations were then larger than when the current was steady - their values were the maximum in decelerating flow. Instantaneous velocities were measured at a section upstream from the heat source in unsteady and steady flows; the results showed that the mean velocity profiles were logarithmic irrespective of the flow state. Both the turbulence intensity in the mean flow direction and the Reynolds shear stress in the decelerating flows were substantially larger than those measured when the flows were accelerating. These results agreed reasonably well with those obtained in estuarine flows. The temperature rise at the heat source was 10°C, hence the present results are also applicable to the case in which buoyancy is produced by a difference in concentration of dissolved materials.
PENGEMBANGAN WISATA SEBAGAI DAYA TARIK SITUS RUMAH SANDI DI PERBUKITAN MENOREH KULON PROGO
Authors: Atmoko Temoteus Prasetyo Hadi 
Published: July 2019

ABSTRAKPenelitian ini bertujuan untuk mengetahui bagaimana pengembangan wisata sebagai daya tarik situs Rumah Sandi di Perbukitan Menoreh Kulon Progo. Penelitan ini menggunakan metode penelitian deskriptif kualitatif. Hasil penelitian ini didapat strategi yang dapat disusun dalam pengembanagn situs Rumah Sandi yaitu penambahan jumlah sumberdaya manusia, pengidentifikasian para stakeholder sebagai mitra dalam pengembangan situs Rumah Sandi agar mampu beradaptasi dan dapat memenuhi kebutuhan pendidikan secara optimal, peningkatan kesadaran masyarakat terkait situs Rumah Sandi dan pelestariannya serta peningkatan kualitas pelayanan dengan merencanakan dan merumuskan sesuai kebutuhan pendidikan. Kata kunci: Daya Tarik, Pariwisata, Pengembangan DEVELOPMENT OF TOURISM AS ATTRACTION OF SITUS RUMAH SANDI IN MENOREH HILL KULON PROGO ABSTRACTThis study aims to find out how tourism is developed as an attraction for Situs Rumah Sandi in Menoreh Hills Kulon Progo. This research uses descriptive qualitative research methods. The results of this study obtained a strategy that can be developed in developing the Situs Rumah Sandi, namely increasing the number of human resources, identifying stakeholders as partners in developing Situs Rumah Sandi to be able to adapt and be able to meet education needs optimally, increase public awareness about Situs Rumah Sandi and their preservation and improving service quality by planning and formulating according to educational needs. Keywords: Attraction, Development, Tourism
The efficacy of bleb needling revision with 5-fluorouracil in encapsulated bleb after unsuccessful trabeculectomy
Authors: OKKA Mehmet , MİRZA Enver , OLTULU Refik , BELVİRANLI Selman , GÜNDÜZ Mehmet Kemal 
Published: July 2019

Objectives: To investigate the efficacy of the bleb needling
revision (BNR) procedure with the adjunctive use of 5-Fluorouracil (5-FU) in
encapsulated bleb after unsuccessful trabeculectomy. Methods: We reviewed 16 eyes of 15 subjects who underwent BNR
procedure due to encapsulated
bleb after unsuccessful trabeculectomy. Demographic data, type of glaucoma,
intraocular pressure (IOP) values of pre-BNR, IOP values of post-BNR at first
day, first week and first month, follow up time and complications were recorded
from patients’ files, retrospectively.
Results: The mean follow up time was
53.1 ± 26.4 weeks. The average
time between previous unsuccessful trabeculectomy and BNR was 11.12 ± 8.79 weeks. The mean IOP
of pre-BNR was 26.0 ± 4.4 mmHg and
significantly decreased to 12.4 ± 5.0 mmHg post-BNR at the first day (p &lt;
0.001). The mean IOP values of post-BNR at the first week was 13.3 ± 4.9 mmHg
and at the first month was 14.8 ± 4.8 mmHg. According to the mean IOP of
pre-BNR, the mean IOP values of
post-BNR at the first week and at the first month were significantly lower (p &lt;
0.001 and p &lt; 0.001, respectively). Seven (44%) eyes were achieved success and
eight (50%) eyes were achieved qualified success. One (6%) eye was
classified as the failure.

Conclusion: The bleb needling revision procedure with the
adjunctive use of 5-FU in encapsulated bleb after unsuccessful trabeculectomy
is a simple, useful and repeatable method to restore the dysfunctional bleb.
Implementation of the education for sustainable development strategy in mathematics education through stakeholder cooperation
Authors: Vintere Anna 
Published: July 2019

The author has identified different stakeholder cooperation opportunities to implement strategy for Education for Sustainable Development (ESD) in mathematics education. Measurement for the implementation of the ESD strategy in the mathematics education at Latvia University of Agriculture made by four input indicators determined by the objectives of the UNECE Strategy for ESD: promoting sustainable development through formal, non-formal and informal education, equipping educators with the competence to include ESD in their teaching, teaching tools and materials and research on ESD. The measures have been described based on the experience in different cooperation networks: Baltic Network in AGROMETRICS, Latviaâ€“Lithuania cross-border network for adapting mathematical competences in the socio-economical development (MATNET) and cross-border network for raising competencies in data analysis technologies (LV-LT-BY DATA ANALYSIS), as well as in cooperation with study program directors, professional associations, employers, authorities, etc.
Keywords: Sustainable development, education for sustainable development, mathematics education, competencies, stakeholder cooperation.
KINETIKA PENGERINGAN TEMU HITAM (Curcuma aeruginosa Roxb.) MENGGUNAKAN CABINET DRYER DENGAN PERLAKUAN PENDAHULUAN BLANCHING
Authors: Sujarwo Baskoro Aji , Amanto Bambang Sigit , Siswanti Siswanti 
Published: July 2019

<p>Temu Hitam (Curcuma aeruginosa Roxb.) merupakan salah satu tanaman herbal yang memiliki banyak khasiat. Tujuan dari penelitian ini untuk mengetahui proses pendahuluan berupa blanching dan juga penggunaan variasi suhu pengering dapat berpengaruh terhadap kinetika pengeringan, kualitas mutu produk simplisia temu<br />hitam dan juga efisiensi alat pengering cabinet dryer. Dari penelitian ini diketahui bahwa perlakuan suhu dan perlakuan pendahuluan blanching terhadap simplisia Temu hitam berpengaruh terhadap kinetika pengeringan. Hasil menunjukkan bahwa semakin tinggi suhu pengeringan maka semakin cepat juga pengeringan berlangsung<br />sampai dengan batas kadar air aman produk simplisia yaitu ≤ 10%. Kualitas mutu produk simplisia temu hitam menunjukkan bahwa penggunaan masing – masing suhu telah memenuhi standar kadar air maksimum simplisia. Untuk kadar kurkumin terbaik sebesar 8,48 % pada penggunaan suhu pengering 50C hal ini menunjukkan<br />penggunaan suhu tinggi pada proses pengeringan dapat mempengaruhi kandungan kurkumin dalam temu hitam. <br />Kata kunci : Temu Hitam, Blanching, Kurkumin, Kinetika Pengeringan, cabinet dryer</p>
SIFAT FISIK, KIMIA, DAN ORGANOLEPTIK PADA PEMBUATAN DODOL YANG DISUBSTITUSI DENGAN WORTEL (Daucus carota, Linn) Basito 1
Authors: Basito Basito 
Published: July 2019

<p>Dodol merupakan makanan semi basah yang pembuatannya dari tepung beras ketan, santan kelapa, dan gula dengan atau tanpa penambahan bahan makanan dan bahan tambahan makanan lain yang diijinkan. Untuk memperbaiki nilai gizi pada dodol dapat dilakukan dengan menambah bahan – bahan lain sebagai sumber vitamin salah satunya adalah wortel. Umbi wortel mengandung karoten dalam jumlah yang tinggi, sehingga berpotensi sebagai sumber vitamin A. Penelitian ini bertujuan untuk mengetahui pengaruh substitusi wortel<br />dalam pembuatan dodol terhadap sifat kimia, fisik dan organoleptik dodol. <br /> Penelitian ini menggunakan Rancangan Acak Lengkap Faktorial dengan 3 kali ulangan. Ada 2 variabel dalam rancangan penelitian ini yaitu variabel tetap dan variabel tidak tetap. Variabel tetap dalam penelitian ini adalah variasi bentuk penambahan wortel (bubur wortel dan tepung wortel) dan variasi konsentrasi wortel dan tepung beras ketan (40:60, 30:70, 20:80, dan 0:100 (kontrol)). Sedangkan variabel tidak tetap yang diamati adalah sifat kimia meliputi: kadar air, karoten dan sifat fisik meliputi: tekstur, serta sifat organoleptik (warna,<br />aroma, rasa, tekstur, dan keseluruhan). Data yang diperoleh dianalisis dengan menggunakan Metode Univariate kemudian dilanjutkan dengan menggunakan Uji Duncan Multiple Range Test (DMRT) pada taraf signifikasi 5%. Dari hasil penelitian dapat disimpulkan bahwa substitusi wortel dalam bentuk bubur maupun tepung<br />wortel pada pembuatan dodol dengan variasi konsentrasi wortel dan tepung ketan berpengaruh terhadap kadar air, karoten dan tekstur dodol yang dihasilkan. Pada uji organoleptik menunjukkan bahwa dodol yang disukai adalah dodol dengan penambahan wortel dalam bentuk bubur wortel dengan konsentrasi bubur wortel dan tepung ketan 30:70. Dodol tersebut mengandung air 17,57%, karoten 9,26 µg/g, dan memiliki tingkat kekerasan 2,24 N serta tingkat elastisitas 6,16 mm. <br />Kata kunci: dodol, wortel, sifat kimia, sifat fisik, sifat organoleptik</p>
UJI POTENSI ANTIDIARE Lactobacillus sp INDIGENOUS SEBAGAI KULTUR STARTER PADA YOGURT DENGAN SUPLEMENTASI EKSTRAK UBI JALAR UNGU
Authors: Tari Intan Niken , Handayani Catur Budi 
Published: July 2019

<p><em>Penelitian ini dilakukan dengan tujuan melihat trend sifat anti diare baik secara kualitatif maupun secara kuantitatif dari BAL pada yogurt dengan suplementasi ubi jalar ungu selama satu minggu penyimpanan. Adapun perlakuan tersebut sebagai berikut : S0= Kontrol ( berupa kultur komersial St dan Lb, S1= Kultur komersial + probiotik Lactobacillus plantarum Dad 13, yaitu St : Lb : Dad 13= 1:1:0.5, S2= Kultur komersial + probiotik Lactobacillus plantarum Mut7, yaitu St : Lb : Mut7 = 1:1:0.5, S3= Kultur komersial+ probiotik Lactobacillus acidophilus SNP-2 yaitu St : Lb : SNP-2 = 1:1:0.5. Hasil penelitian menunjukkan bahwa aktifitas antidiare secara kualitatif lactobacillus sp indigenous terhadap EPEC ATCC 35281 terbesar terjadi pada perlakuan Y1 (yogurt dengan probiotik lactobacillus plantarum Dad 13 dan suplementasi ekstrak ubi jalar ungu) dengan diameter zona hambat sebesar 12, 8 mm. Aktifitas antidiare secara kuantitatif lactobacillus plantarum sp indigenous terhadap EPEC ATCC 35281 selama 1minggu penyimpanan terbesar, juga terjadi pada perlakuan Y1 (yogurt dengan probiotik Llactobacillus plantarum Dad 13 dan suplementasi ekstrak ubi jalar ungu) dengan kemampuan penurunan jumlah koloni EPEC ATCC 35281 sebesar 5 log cycle (dari mula-mula 1,05. 10<sup>7</sup> CFU/ml menjadi 8,5. 10<sup>2</sup> CFU/ml)</em></p>
Clinical evaluation of transarterial infusion chemotherapy for advanced esophageal cancer
Authors: Zeng Yan-Wei , Yin Mei-Pan , Zhao Yue , He Wei , Ma Yao-Zhen , Li Chun-Xia , Wu Gang 
Published: July 2019

Abstract
Background:Most esophageal cancer patients were diagnosed at an advanced stage where there are few effective treatment. Transarterial infusion chemotherapy(TAI) is a local chemotherapy method wherein chemotherapeutic drugs are directly injected into tumor vessels. Methods: TAI was performed on advanced esophageal carcinoma patients once a month, and each patient underwent 1–3 treatments. The clinical results, complications, and effectiveness rates of each treatment episode were recorded and analyzed. Results: TAI was successfully performed in all patients, and no severe complications such as paraplegia or death were noted. Complete response (CR), partial response (PR), and stable disease (SD) were noted in 17.3% (13/75), 77.3% (58/75), and 5.3% (4/75) of cases after TAI, respectively. The total treatment efficacy (CR+PR) was 94.7%. All cases exhibited improvement in clinical stages, with a marked decrease in dysphagia. Subsequent treatments were administered to 13 patients, including radical radiation in 7 and chemotherapy in 6. During follow-up, death was caused by progressive carcinoma in 20, tumor-related pneumatic infection and respiratory failure in 11, and gastrointestinal hemorrhage in 17. The median survival time was 15 months and the 1-year survival rate was 58.1%. Conclusions: TAI chemotherapy may be safely used for advanced esophageal carcinoma treatment.
Nuclear Factor I A Promotes Temozolomide Resistance in Glioblastoma via Transcriptional Regulation of Nuclear Factor κB Pathway
Authors: Yu Xiao , Wang Maode , Zuo Jie , Wahafu Alafate , Li Ruichun , Wu Wei , Liu Chao , Xie Wanfu , Wang Jia 
Published: July 2019

Abstract
Background: Glioma is one of the most common primary brain tumors in human with severe mortality based on its therapy resistance and recurrence. Many molecular pathways and regulation factors have been proved to be required for GBM growth and therapy resistance, however, the underlying molecular mechanisms still remains unclear.
Methods: Nuclear factor I-A (NFIA) was identified as a key candidate kinase encoding gene in chemoresistance regulation by using kinome-wide bioinformatic analysis. Afterwards, the potential biological functions of NFIA in oncogenesis and chemoresistance were clarified by qRT-PCR, western blotting and in vivo xenograft models followed by temozolomide (TMZ) resistant U87 cell induction. Additionally, immunohistochemistry (IHC) assays were performed to explore the clinical significance of AURKB in glioma patients. At last, lentiviral silencing of NFIA was used to explore the potential downstream targets for NFIA in acquired TMZ resistance in GBM..
Results: We identified NFIA was the most correlated gene for TMZ resistance in GBM. Clinically, elevated NFIA expression was significantly correlated to adverse outcomes of glioma patients especially in GBM patients. Moreover, NFIA was functionally required for TMZ resistance of U87 cells while suppression of NFIA via lentivirus infection reduced cell proliferation, tumorigenesis as well as resistance to TMZ in GBM cells. Lastly, NFIA promoted acquired TMZ resistance in GBM via transcription activity thus regulated the expression of nuclear factor κB (NF-kB).
Conclusions: Altogether, our study suggests that NFIA-dependent transcriptional regulation of NF-kB contributes to the acquired TMZ resistance in GBM, indicating that NFIA-NF-κB axis could be a new therapeutic target for TMZ resistant GBM.