bluuebunny/crossref_metadata_2025_split huggingface dataset:
Automated Translation of Clinical Parameters in Evaluating Acute Radiation Injury: Results From a Mass Casualty Exercise
Authors: Dant James T. , Reeves Glen , Stricklin Daniela 
Published: March 2018

AbstractObjectiveA radiological disaster could result in a large number of patients potentially exposed to harmful levels of radiation. Currently, early triage of patients for radiation exposure relies heavily on a clinical evaluation of signs and symptoms. However, detailed clinical assessment takes significant time and requires specialized training to accurately interpret the results.MethodsDuring planning of a recent exercise, SMEs estimated that it would take up to 15 minutes per patient. Patient load would quickly overwhelm the number of qualified clinicians providing treatment. In this exercise organized by the NATO RTG HFM 222, we examined using automated translation of clinical data to facilitate clinic evaluations. We used two triage evaluation approaches; REAC/TS and METREPOL. These approaches allowed us to translate tabulated clinical data, first into categorical data for grouping patients, and then into recommendations for follow-up diagnostics and care.ResultsThe organizers provided clinical evaluations of 191 case studies that were estimated to require up to 50 total hours for completion. However, using our application, we were able to evaluate all cases in less than 2 minutes.ConclusionThis study clearly demonstrates the need for automated tools to help translate clinical data for effective patient triage after a nuclear or radiological incident. (Disaster Med Public Health Preparedness. 2018;12:569–573)
Zika Virus Preparedness and Response Efforts Through the Collaboration Between a Health Care Delivery System and a Local Public Health Department
Authors: Madad Syra , Tate Anna , Rand Maytal , Quinn Celia , Vora Neil M. , Allen Machelle , Cagliuso Nicholas V. , Rakeman Jennifer L. , Studer Sean , Masci Joseph , Varma Jay K. , Wilson Ross 
Published: March 2018

ABSTRACTThe Zika virus was largely unknown to many health care systems before the outbreak of 2015. The unique public health threat posed by the Zika virus and the evolving understanding of its pathology required continuous communication between a health care delivery system and a local public health department. By leveraging an existing relationship, NYC Health+Hospitals worked closely with New York City Department of Health and Mental Hygiene to ensure that Zika-related processes and procedures within NYC Health+Hospitals facilities aligned with the most current Zika virus guidance. Support given by the public health department included prenatal clinical and laboratory support and the sharing of data on NYC Health+Hospitals Zika virus screening and testing rates, thus enabling this health care delivery system to make informed decisions and practices. The close coordination, collaboration, and communication between the health care delivery system and the local public health department examined in this article demonstrate the importance of working together to combat a complex public health emergency and how this relationship can serve as a guide for other jurisdictions to optimize collaboration between external partners during major outbreaks, emerging threats, and disasters that affect public health. (Disaster Med Public Health Preparedness. 2018;12:689-691)
Hegel and Arguments for Natural Kind Essentialism
Authors: Knappik Franz 
Published: March 2018

AbstractNatural Kind Essentialism (NKE) is the view that the objects of sciences like physics, chemistry and biology fall into natural kinds, and that such kinds have essences—sets of properties possession of which is necessary and sufficient for kind-membership. Since Putnam and Kripke brought NKE back onto the philosophical agenda, it has found many advocates. But comparatively little attention has been paid to the question of how this view can be positively motivated. After illustrating the current need for an argument for NKE through critical discussions of Putnam’s, Kripke’s and Ellis’s arguments for NKE, this article aims to show that Hegel offers the resources for an original argument for the view. This argument works by deriving metaphysical implications from an account of what it means to understand an explanandum.
Warm-based basal sediment entrainment and far-field Pleistocene origin evidenced in central Transantarctic blue ice through stable isotopes and internal structures
Authors: GRALY JOSEPH A. , LICHT KATHY J. , KASSAB CHRISTINE M. , BIRD BROXTON W. , KAPLAN MICHAEL R. 
Published: March 2018

ABSTRACTStable isotopes of water (δ18O and δ2H) were measured in the debris-laden ice underlying an Antarctic blue ice moraine, and in adjoining Law Glacier in the central Transantarctic Mountains. Air bubble content and morphology were assessed in shallow ice core samples. Stable isotope measurements plot either on the meteoric waterline or are enriched from it. The data cluster in two groups: the ice underlying the moraine has a δ2H:δ18O slope of 5.35 ± 0.92; ice from adjoining portions of Law Glacier has a slope of 6.69 ± 1.39. This enrichment pattern suggests the moraine's underlying blue ice entrained sediment through refreezing processes acting in an open system. Glaciological conditions favorable to warm-based sediment entrainment occur 30–50 km upstream. Basal melting and refreezing are further evidenced by abundant vapor figures formed from internal melting of the ice crystals. Both the moraine ice and Law Glacier are sufficiently depleted of heavy isotopes that their ice cannot be sourced locally, but instead must be derived from far-field interior regions of the higher polar plateau. Modeled ice flow speeds suggest the ice must be at least 80 ka old, with Law Glacier's ice possibly dating to OIS 5 and moraine ice older still.
Controls on rapid supraglacial lake drainage in West Greenland: an Exploratory Data Analysis approach
Authors: WILLIAMSON ANDREW G. , WILLIS IAN C. , ARNOLD NEIL S. , BANWELL ALISON F. 
Published: March 2018

ABSTRACTThe controls on rapid surface lake drainage on the Greenland ice sheet (GrIS) remain uncertain, making it challenging to incorporate lake drainage into models of GrIS hydrology, and so to determine the ice-dynamic impact of meltwater reaching the ice-sheet bed. Here, we first use a lake area and volume tracking algorithm to identify rapidly draining lakes within West Greenland during summer 2014. Second, we derive hydrological, morphological, glaciological and surface-mass-balance data for various factors that may influence rapid lake drainage. Third, these factors are used within Exploratory Data Analysis to examine existing hypotheses for rapid lake drainage. This involves testing for statistical differences between the rapidly and non-rapidly draining lake types, as well as examining associations between lake size and the potential controlling factors. This study shows that the two lake types are statistically indistinguishable for almost all factors investigated, except lake area. Thus, we are unable to recommend an empirically supported, deterministic alternative to the fracture area threshold parameter for modelling rapid lake drainage within existing surface-hydrology models of the GrIS. However, if improved remotely sensed datasets (e.g. ice-velocity maps, climate model outputs) were included in future research, it may be possible to detect the causes of rapid drainage.
Clinical validation of the Psychotic Depression Assessment Scale (PDAS) against independent global severity ratings in older adults
Authors: Vermeulen Tom , Lemey Lieve , Van Diermen Linda , Schrijvers Didier , Madani Yamina , Sabbe Bernard , Van Den Bossche Maarten J.A. , van der Mast Roos C. , Østergaard Søren D. 
Published: March 2018

AbstractObjectivesAccording to a recent study, ratings on the Psychotic Depression Assessment Scale (PDAS) obtained via a dedicated semi-structured interview are valid measures of the severity of psychotic depression. This study aimed to further test the validity, scalability and responsiveness of the PDAS in older adults using independent ratings on the Clinical Global Impression Scale – Severity (CGI-S) and the Montgomery-Asberg Depression Rating Scale (MADRS) as references.MethodsRatings were performed at admission and discharge at two old age psychiatric wards in Flanders, Belgium. In total, 62 older adults (mean age: 74.3 years) with psychotic depression were included. The PDAS was rated by trained nurses using the semi-structured PDAS interview. Senior psychiatrists scored the participants on the CGI-S. Psychologists or experienced nurses rated participants on the MADRS. Clinical validity was assessed by correlating the PDAS total scores with CGI-S ratings and MADRS total scores. Mokken analysis was performed to assess the scalability of the PDAS. Responsiveness was assessed by comparing the proportion of participants in remission (PDAS total score <8 at study baseline and endpoint).ResultsThe Spearman correlation coefficients were 0.76 and 0.79 for the PDAS versus CGI-S and PDAS versus MADRS, respectively. The Mokken analysis yielded a Loevinger coefficient of 0.46, which is indicative of scalability. At admission, no participants met the PDAS remission criterion. At discharge, 54% (95% confidence interval: 47%–60%) of the patients met this criterion.ConclusionThe PDAS appears to be a clinically valid, scalable and responsive measure of the severity of psychotic depression in older adults.
Projections for Future Radiocarbon Content in Dissolved Inorganic Carbon in Hardwater Lakes: A Retrospective Approach
Authors: Blattmann Thomas M , Wessels Martin , McIntyre Cameron P , Eglinton Timothy I 
Published: March 2018

ABSTRACTInland water bodies contain significant amounts of carbon in the form of dissolved inorganic carbon (DIC) derived from a mixture of modern atmospheric and pre-aged sources, which needs to be considered in radiocarbon-based dating and natural isotope tracer studies. While reservoir effects in hardwater lakes are generally considered to be constant through time, a comparison of recent and historical DI14C data from 2013 and 1969 for Lake Constance reveals that this is not a valid assumption. We hypothesize that changes in atmospheric carbon contributions to lake water DIC have taken place due to anthropogenically forced eutrophication in the 20th century. A return to more oligotrophic conditions in the lake led to reoxygenation and enhanced terrigenous organic matter remineralization, contributing to lake water DIC. Such comparisons using DI14C measurements from different points in time enable nonlinear changes in lake water DIC source and signature to be disentangled from concurrent anthropogenically induced changes in atmospheric 14C. In the future, coeval changes in lake dynamics due to climate change are expected to further perturb these balances. Depending on the scenario, Lake Constance DI14C is projected to decrease from the 2013 measured value of 0.856 Fm to 0.54–0.62 Fm by the end of the century.
Choosing the Velvet Glove: Women Voters, Ambivalent Sexism, and Vote Choice in 2016
Authors: Frasure-Yokley Lorrie 
Published: March 2018

AbstractThis paper examines the extent to which ambivalent sexism toward women influenced vote choice among American women during the 2016 Presidential election. I examine how this varied between white women and women of color. The 2016 American National Election Study (ANES) features several measures from the Ambivalent Sexism Inventory (ASI)—a scale developed by Glick and Fiske (1996) to assess sexist attitudes toward women. An index of these measures is used to examine the extent to which ambivalent sexist attitudes influenced women's vote choice for Donald Trump, controlling for racial resentment, partisanship, attitudes toward immigrants, economic anxiety, and socio-demographics. On the one hand, my findings indicate that ambivalent sexism was a powerful influence on women's Presidential vote choice in 2016, controlling for other factors. However, this finding, based on a model ofall women votersis misleading, once an intersectional approach is undertaken. Once the data are disaggregated by gender and race, white women's political behavior proves very different than women of color. Among white women, ambivalent sexist views positively and significantly predicts vote choice for Trump, controlling for all other factors. However, for women of color, this relationship was negative and posed no statistical significant relationship to voting for Trump. Scholarship in gender and politics that does not account for group differences in race/ethnicity may present misleading results, which are either underestimated or overestimated.
Differential growth performance and intestinal immune gene expression in diverse genetic lines of growing chickens fed a high concentration of supplemental phytase
Authors: Jiang S. Q. , Lamont S. J. , Persia M. E. 
Published: March 2018

AbstractThe objective of the current experiment was to determine the effects of high-concentration phytase (5000 FTU/kg) feeding to diverse lines of chickens fed phosphorus (P) adequate maize–soybean meal diets (4.5 g/kg non-phytate P) on the performance and intestinal immune function. Performance was measured for outbred broiler (Ross 308) and inbred Fayoumi lines over 0–21 days, and duodenum and ileum were harvested for the determination of mucin-2, interleukin (IL)-1βand IgA mRNA by quantitative reverse transcription polymerase chain reaction. Over the 0–7-day period, there was a significant line × diet interaction, as high phytase supplementation increased broiler average daily gain (ADG), but had no effect on Fayoumi ADG. Treatment of diets with phytase increased expression of the mucin-2 gene in the duodenum mucosa. There were significant interactions between line and age, and line, diet and age on duodenal expression of the IL-1βgene as phytase supplementation of the broiler line reduced IL-1βin comparison to control fed broilers without change in the Fayoumi line. Overall, the addition of a high concentration of phytase to broilers fed adequate concentrations of non-phytate P resulted in improved growth performance early with a reduction in this effect over time. Mucosal mucin-2 expression was increased with high-concentration phytase feeding across both lines, but IL-1βmRNA expression was reduced in the duodenum of broilers fed high concentrations of phytase, suggesting that the increased performance noted might be related to decreased inflammation.
Co-occurrence of snow leopard Panthera uncia, Siberian ibex Capra sibirica and livestock: potential relationships and effects
Authors: Rovero Francesco , Augugliaro Claudio , Havmøller Rasmus Worsøe , Groff Claudio , Zimmermann Fridolin , Oberosler Valentina , Tenan Simone 
Published: March 2018

AbstractUnderstanding the impact of livestock on native wildlife is of increasing conservation relevance. For the Vulnerable snow leopard Panthera uncia, wild prey reduction, intensifying human–wildlife conflicts and retaliatory killings are severe threats potentially exacerbated by the presence of livestock. Elucidating patterns of co-occurrence of snow leopards, wild ungulate prey, and livestock, can be used to assess the compatibility of pastoralism with conservation. We used camera trapping to study the interactions of livestock, Siberian ibex Capra sibirica and snow leopards in a national park in the Altai mountains, Mongolia. We obtained 494 detections of wild mammals and 912 of domestic ungulates, dogs and humans. Snow leopards and Siberian ibex were recorded 14 and 33 times, respectively. Co-occurrence modelling showed that livestock had a higher estimated occupancy (0.65) than ibex, whose occupancy was lower in the presence of livestock (0.11) than in its absence (0.34–0.35 depending on scenarios modelled). Snow leopard occupancy did not appear to be affected by the presence of livestock or ibex but the robustness of such inference was limited by uncertainty around the estimates. Although our sampling at presumed snow leopard passing sites may have led to fewer ibex detections, results indicate that livestock may displace wild ungulates, but may not directly affect the occurrence of snow leopards. Snow leopards could still be threatened by livestock, as overstocking can trigger human–carnivore conflicts and hamper the conservation of large carnivores. Further research is needed to assess the generality and strength of our results.
What accounts for poor functioning in people with schizophrenia: a re-evaluation of the contributions of neurocognitive v. attitudinal and motivational factors
Authors: Beck Aaron T. , Himelstein Robyn , Bredemeier Keith , Silverstein Steven M. , Grant Paul 
Published: March 2018

AbstractBackgroundNeurocognitive deficits are often seen as core features of schizophrenia, and as primary determinants of poor functioning. Yet, our clinical observations suggest that individuals who score within the impaired range on standardized tests can reliably perform better in complex real-world situations, especially when performance is embedded within a positive socio-affective context.MethodsWe analyzed literature on the influence of non-neurocognitive factors on test performance in order to clarify their contributions.ResultsWe identified seven non-neurocognitive factors that significantly contribute to neurocognitive test performance: avolition, dysfunctional attitudes, effort, stress, negative emotions, asociality, and disorganized symptoms. We then proposed an alternative model based on dysfunctional (e.g. defeatist) attitudes and their consequences for motivation and sustained task engagement. We demonstrated that these factors account for substantial variance in negative symptoms, neurocognitive test performance, and functional outcomes. We then demonstrated that recovery-oriented cognitive therapy – which is derived from this alternative model and primarily targets dysfunctional beliefs – has been successful in the treatment of low functioning individuals with schizophrenia.ConclusionThe contributions of neurocognitive impairments to poor real-world functioning in people with schizophrenia may be overstated in the literature, and may even be limited relative to non-neurocognitive factors. We offer suggestions for further research to more precisely quantify the contributions of attitudinal/motivation v. neurocognitive factors in schizophrenia.
Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort
Authors: Escott-Price Valentina , Smith Daniel J. , Kendall Kimberley , Ward Joey , Kirov George , Owen Michael J. , Walters James , O'Donovan Michael C. 
Published: March 2018

AbstractBackgroundThere is strong evidence that people born in winter and in spring have a small increased risk of schizophrenia. As this ‘season of birth’ effect underpins some of the most influential hypotheses concerning potentially modifiable risk exposures, it is important to exclude other possible explanations for the phenomenon.MethodsHere we sought to determine whether the season of birth effect reflects gene-environment confounding rather than a pathogenic process indexing environmental exposure. We directly measured, in 136 538 participants from the UK Biobank (UKBB), the burdens of common schizophrenia risk alleles and of copy number variants known to increase the risk for the disorder, and tested whether these were correlated with a season of birth.ResultsNeither genetic measure was associated with season or month of birth within the UKBB sample.ConclusionsAs our study was highly powered to detect small effects, we conclude that the season of birth effect in schizophrenia reflects a true pathogenic effect of environmental exposure.
Living arrangement preferences and realities for elderly Chinese: implications for subjective wellbeing
Authors: CHEN TAICHANG 
Published: March 2018

ABSTRACTThis article investigates the determinants of preference for intergenerational co-residence and examines the effects of living arrangement concordance (i.e.having a match between preference and reality) on the subjective wellbeing (SWB) of older Chinese. Data were derived from the China Health and Retirement Longitudinal Study (CHARLS) national baseline conducted in 2011. This allows for two different measures of the affective approach to SWB: depression and happiness. This article found living arrangement preference is indicative of need, cultural norms and current living arrangement experiences. The results support the hypothesis of discrepancy theories that having living arrangement concordance improves older parents’ SWB (i.e.depressive symptoms and happiness). In addition, the previously predictive effects of the actual living arrangement on SWB lost significance when actual living arrangement and concordance were added simultaneously. Living in a preferred arrangement appears to be more important than living in a traditional arrangement from the point of view of older adults’ SWB. Programmes designed to improve wellbeing in later life should not assume that there is a one-size-fits-all model for all; instead, older people should be given more choices of living arrangements.
Social participation perspectives of people with cognitive problems and their care-givers: a descriptive qualitative study
Authors: DONKERS HANNEKE , VERNOOIJ-DASSEN MYRRA , VAN DER VEEN DINJA , VAN DER SANDEN MARIA NIJHUIS , GRAFF MAUD 
Published: March 2018

ABSTRACTThe aim of this study is to explore how community-dwelling older people with cognitive problems and their care-givers (dyads) perceive their own social participation, how care-givers evaluate the social participation of the people they care for and what factors they perceive as influential. In this qualitative study, we performed 13 semi-structured, in-depth interviews with dyads who participated in the Social Fitness Programme. We used content analysis to analyse the interviews thematically. Social participation perceptions include changes over time and a discrepancy in perspectives. All the people with cognitive problems and most care-givers perceived a decreased social participation. Most people with cognitive problems answered that they were satisfied, in contrast to most care-givers who were dissatisfied with the decreased social participation of the people they cared for. Analysing the influencing factors resulted in five themes: behavioural, physical, social environmental, physical environmental and activity-related. People with cognitive problems and their care-givers displayed a discrepancy in social participation perspectives. This becomes a major dilemma, especially for younger care-givers. A key element is a sometimes deliberate choice of people with cognitive problems to refrain from social participation to protect themselves from the consequences of cognitive problems and from encounters with others. This highlights the dynamics of social participation as an interaction between personal factors and the social and physical environment in which social participation occurs.