bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complementors' engagement in an ecosystem: A study of publishers' e‐book offerings on Amazon Kindle
Authors: Wang Richard D. , Miller Cameron D. 
Published: August 2019

AbstractResearch SummaryIn ecosystems, tensions between value creation and appropriation can arise when complementors form relationships with a partner that benefits from network effects. While creating value collectively, these relationships strengthen the network effects, which increase the partner's ability to appropriate value. We posit that complementors strategize their product offerings to benefit from the relationship with the partner while preserving bargaining power by keeping relationships with other partners as outside options. We examine book publishers' product portfolios in the Amazon Kindle e‐book and the printed book ecosystems. Our results illuminate specific product offering decisions by large publishers that are more protective of the printed book ecosystem and less conducive to Kindle's success. This research adds to the literature on interorganizational relationships, platform ecosystems, and managing digital innovations.Managerial SummaryHow do book publishers deal with Amazon? This paper compares book publishers' product offerings on Amazon's Kindle digital platform and in the physical print channel. We find that publishers offer high demand products as e‐books on Kindle to benefit from logistics savings. Yet, relative to small publishers, large publishers product decisions that support Kindle less, such as withholding some of their greatest revenue generating books. Such decisions could both limit Kindle's attractiveness to the consumers and preserve the economic viability of the print channel as an outside option. These findings improve our understanding of how companies can leverage their product portfolios to both benefit from digital technology efficiencies and maintain their bargaining power vis‐à‐vis digital platforms.
Accessed or latent resources? Exploring new secondary science teachers' networks of resources
Authors: Navy Shannon L. , Nixon Ryan S. , Luft Julie A. , Jurkiewicz Melissa A. 
Published: August 2019

AbstractAlthough new teachers clearly need resources and support, little is known about the types of resources new science teachers' access during their early years of teaching. To increase knowledge of their needs, the study described in this article focused on the primary resources (i.e., human, material, and social) and secondary resources (i.e., strategic and symbolic) new science teachers' access and how those resources interact in new teachers' instructional contexts. The participants for this qualitative study were 15 new secondary science teachers in the United States, and data sources included a contextual interview, teaching observations, and a follow‐up interview. Findings revealed that these teachers had a variety of resources available to them, of which social resources were particularly important. Some resources were not accessed and remained latent resources. In addition, some interactions of resources in the new teachers' context led to the development of the network of resources model to represent how resources can interact in contexts to support a new teacher. This model highlights the importance of considering the interaction of multiple resources in a teaching context.
Effects of environmental chemicals on the proliferation and differentiation of neural stem cells
Authors: Huang Min , Li Yingying , Wu Kexin , Hao Shaowen , Cai Qian , Zhou Zhi‐jun , Yang Hui‐fang 
Published: August 2019

AbstractThe objective of the present study was to explore the effects of environmental chemicals, such as methyl mercury, paraquat, and bisphenol A, on cell proliferation and apoptosis, as well as the expression levels of neuronal differentiation‐related genes in neural stem cells (NSCs). NSCs originated from human umbilical cord blood (HUCB‐NSCs) were used as cell models in the current study. CCK‐8 and flow cytometry experiments were performed to assess the effects of methyl mercury, paraquat, and bisphenol A on the proliferation and apoptosis of HUCB‐NSCs at different processes, including proliferation and differentiation stages. The expressions of neuronal differentiation‐related genes were determined by reverse transcription‐polymerase chain reaction and western blot analysis. The results showed that methyl mercury, paraquat, and bisphenol A treatments significantly inhibited cell proliferation and induced cell apoptosis in HUCB‐NSCs, as well as decreased the expressions of Oct4, Gdf3, and Sox1, whereas increased Pax6 and Ngn1 expressions at both mRNA and protein levels. In conclusion, this study demonstrates that environmental chemicals can impair the proliferation and differentiation of NSCs, which may cause abnormal development of the nervous system.
Correction to: Mathematics and Computation in Music
Authors: Montiel Mariana , Gomez-Martin Francisco , Agustín-Aquino Octavio A. 
Published: August 2019

Maria Mannone was not given credit for the cover logo in the original version. This was corrected.The original version of chapter 14, “Distant Neighbors and Interscalar Contiguities” was revised. This chapter was previously published non-open access. It was changed to open access retrospectively under a CC BY 4.0 license. The book has also been updated with the change.
Effects of primary care cost-sharing among young adults: varying impact across income groups and gender
Authors: Johansson Naimi , Jakobsson Niklas , Svensson Mikael 
Published: August 2019

AbstractWe estimate the price sensitivity in health care among adolescents and young adults, and assess how it varies across income groups and gender, using a regression discontinuity design. We use the age differential cost-sharing in Swedish primary care as our identification strategy. At the 20th birthday, the copayment increases from €0 to approx. €10 per primary care physician visit and close to this threshold the copayment faced by each person is distributed almost as good as if randomized. The analysis is performed using high-quality health care and economic register data of 73,000 individuals aged 18–22. Our results show that the copayment decreases the average number of visits by 7%. Among women visits are reduced by 9%, for low-income individuals by 11%, and for low-income women by 14%. In conclusion, modest copayments have significant utilization effects, and even in a policy context with relatively low income inequalities, the effect is substantially larger in low-income groups and among women.
A Systematic Review of eHealth Interventions Addressing HIV/STI Prevention Among Men Who Have Sex With Men
Authors: Nguyen Long Hoang , Tran Bach Xuan , Rocha Luis E. C. , Nguyen Huong Lan Thi , Yang Cui , Latkin Carl A. , Thorson Anna , Strömdahl Susanne 
Published: August 2019

Abstract
A systematic review was conducted to summarize and appraise the eHealth interventions addressing HIV/STI prevention among men who have sex with men (MSM), and characterize features of successful eHealth interventions. Fifty-five articles (17 pilots and 38 full efficacy trials) were included with the predominance of web-based interventions in the United States-based settings. Intervention modalities include web-based, short message service (SMS)/text messges/email reminder, online video-based, computer-assisted, multimedia-based, social network, live chat and chat room, virtual simulation intervention, and smartphone applications. Forty-nine eHealth interventions achieved a short-term behaviour change among participants. Four studies were conducted with 12-month follow-ups; and only one of them could maintain the behaviour change over this longer time period which could be due to the lack of booster interventions. Our study suggests that eHealth interventions can achieve short term behaviour change among MSM, however limited interventions could maintain behaviour change over 12 months. Further eHealth intervention strategies to promote HIV prevention among MSM should be conducted and rigorously evaluated.
Direct and indirect effects of strength‐based parenting on adolescents’ school outcomes: Exploring the role of mental toughness
Authors: Sağkal Ali Serdar 
Published: August 2019

ABSTRACTIntroductionStrength‐based parenting defined as recognizing and cultivating strengths in children is potentially linked to important child and adolescent outcomes. In this study, direct and indirect effects (via mental toughness) of strength‐based parenting on adolescents’ school outcomes, particularly, school engagement and burnout were examined.MethodsThe sample consisted of 350 high school students (ages 14–18 years; 49.7% female) using multistage cluster sampling from central school district of city of Aydın, Turkey. Participants completed a battery of questionnaires that assess strength‐based parenting, mental toughness, school engagement, and burnout.ResultsResults showed that strength‐based parenting is significantly and directly related to higher levels of school engagement, but not to school burnout. Furthermore, indirect effects of strength‐based parenting on both school engagement and burnout through the mechanism of mental toughness were statistically significant. A series of multigroup post hoc analyses suggested that the structural model was robust across gender and age.ConclusionsThe present findings suggest that strength‐based parenting plays a crucial role on adolescents’ school outcomes and these links are mediated by mental toughness. Implications and suggestions for future research are also discussed.
Cost‐effectiveness of a collaborative dementia care management—Results of a cluster‐randomized controlled trial
Authors: Michalowsky Bernhard , Xie Feng , Eichler Tilly , Hertel Johannes , Kaczynski Anika , Kilimann Ingo , Teipel Stefan , Wucherer Diana , Zwingmann Ina , Thyrian Jochen René , Hoffmann Wolfgang 
Published: August 2019

AbstractIntroductionThe purpose of this study was to determine the cost‐effectiveness of collaborative dementia care management (DCM).MethodsThe cost‐effectiveness analysis was based on the data of 444 patients of a cluster‐randomized, controlled trial, conceptualized to evaluate a collaborative DCM that aimed to optimize treatment and care in dementia. Health‐care resource use, costs, quality‐adjusted life years (QALYs), and incremental cost per QALY gained were measured over a 24‐month time horizon.ResultsDCM increased QALYs (+0.05) and decreased costs (−569€) due to a lower hospitalization and a delayed institutionalization (7 months) compared with usual care. The probability of DCM being cost‐effective was 88% at willingness‐to‐pay thresholds of 40,000€ per QALY gained and higher in patients living alone compared to those not living alone (96% vs. 26%).DiscussionDCM is likely to be a cost‐effective strategy in treating dementia and thus beneficial for public health‐care payers and patients, especially for those living alone.
Middle‐ and High‐Latitude Mesosphere and Lower Thermosphere Mean Winds and Tides in Response to Strong Polar‐Night Jet Oscillations
Authors: Conte J. Federico , Chau Jorge L. , Peters Dieter H. W. 
Published: August 2019

AbstractThe dynamical behavior of the mesosphere and lower thermosphere (MLT) region during strongly disturbed wintertime conditions commonly known as polar‐night jet oscillations (PJOs) is described in detail and compared to other wintertime conditions. For this purpose, wind measurements provided by two specular meteor radars located at Andenes (69°N, 16°E) and Juliusruh (54°N, 13°E) are used to estimate horizontal mean winds and tides as an observational basis. Winds and tidal main features are analyzed and compared for three different cases: major sudden stratospheric warming (SSW) with (a) strong PJO event, (b) non‐PJO event, and (c) no major SSWs. We show that the distinction into strong PJOs, non‐PJOs, and winters with no major SSWs is better suited to identify differences in the behavior of the mean winds and tides during the boreal winter. To assess the impact of the stratospheric disturbed conditions on the MLT region, we investigate the 30‐year nudged simulation by the Extended Canadian Middle Atmosphere Model. Analysis of geopotential height disturbances suggests that changes in the location of the polar vortex at mesospheric heights are responsible for the jets observed in the MLT mean winds during strong PJOs, which in turn influence the evolution of semidiurnal tides by increasing or decreasing their amplitudes depending on the tidal component.
Research Applications for the Geostationary Lightning Mapper Operational Lightning Flash Data Product
Authors: Peterson Michael 
Published: August 2019

AbstractThe Lightning Cluster Filter Algorithm in the Geostationary Lightning Mapper (GLM) ground system identifies lightning flashes from the stream of event detections. It excels at clustering simple flashes but experiences anomalies with complex flashes that last longer than 3 s or contain more than 100 groups, leading to flashes being artificially split. We develop a technique that corrects these anomalies and apply it to the 2018 GLM data to document all lightning across the Americas. We produce statistics describing the characteristics and frequencies of reclustered GLM flashes and thunderstorm area features. The average GLM Americas flash rate in 2018 was 11.7 flashes per second with the greatest flash rate densities occurring over Lake Maracaibo (157 flashes per km2/year). Lloró, Chocó, Colombia had the most thunderstorm activity with 256 thunder days. The longest GLM flash spanned 673 km, the largest flash covered 114,997 km2, and the longest‐lasting flash had a 13.496‐s duration. The first case occurred over Rio Grande do Sul in Brazil, while the other two cases occurred in the central United States. All three extreme flashes are located in the stratiform regions of Mesoscale Convective Systems. The highest flash rate for a thunderstorm area feature was 17.6 flashes per second, while the largest thunderstorm was 216,865 km2 in size. Both storms occurred in South America. These initial results demonstrate the value that the development of a reprocessed GLM science product would offer and how such a product might be created at a reduced computational cost.
Volcanic Eruption Signatures in the Isotope‐Enabled Last Millennium Ensemble
Authors: Stevenson S. , Otto‐Bliesner B. L. , Brady E. C. , Nusbaumer J. , Tabor C. , Tomas R. , Noone D. C. , Liu Z. 
Published: August 2019

AbstractExplosive volcanic eruptions are one of the largest natural climate perturbations, but few observational constraints exist on either the climate responses to eruptions or the properties (size, hemispheric aerosol distribution, etc.) of the eruptions themselves. Paleoclimate records are thus important sources of information on past eruptions, often through the measurement of oxygen isotopic ratios (δ18O) in natural archives. However, since many processes affect δ18O, the dynamical interpretation of these records can be quite complex. Here we present results from new, isotope‐enabled members of the Community Earth System Model Last Millennium Ensemble, documenting eruption‐induced δ18O variations throughout the climate system. Eruptions create significant perturbations in the δ18O of precipitation and soil moisture in central/eastern North America, via excitation of the Atlantic Multidecadal Oscillation. Monsoon Asia and Australia also exhibit strong precipitation and soil δ18O anomalies; in these cases, δ18O may reflect changes to El Niño‐Southern Oscillation phase following eruptions. Salinity and seawater δ18O patterns demonstrate the importance of both local hydrologic shifts and the phasing of the El Niño‐Southern Oscillation response, both along the equator and in the subtropics. In all cases, the responses are highly sensitive to eruption latitude, which points to the utility of isotopic records in constraining aerosol distribution patterns associated with past eruptions. This is most effective using precipitation δ18O; all Southern eruptions and the majority (66%) of Northern eruptions can be correctly identified. This work thus serves as a starting point for new, quantitative uses of isotopic records for understanding volcanic impacts on climate.
Analysis of Flow Resistance Equations in Gravel‐Bed Rivers With Intermittent Regimes: Calabrian fiumare Data Set
Authors: Mendicino G. , Colosimo F. 
Published: August 2019

AbstractThis study addresses the evaluation of flow resistance in natural gravel‐bed rivers. Through a new data set collected on 136 reaches of 78 gravel‐bed rivers (Calabrian fiumare) in southern Italy, different conventional flow resistance equations to predict mean flow velocity in gravel‐bed rivers were tested in their original form. These equations have shown considerable disagreement with observed data, especially in river reaches characterized by high bed load conditions and for the domains of intermediate‐ and large‐scale roughness. This disagreement produced in almost all the cases an underestimation of the flow resistance, which can be corrected by introducing the Froude number and a particular form of the Shields sediment mobility parameter into the Manning, Chezy, and Darcy‐Weisbach equations. Through analyses carried out both on the whole data set and on its subsets, we propose a semiempirical approach with which, on the one hand, the tractive forces exerted by the flow on the bed are taken into account by considering the ratio between the sediment mobility parameter and its critical value, and on the other hand, water surface distortions are evaluated using the Froude number. This approach has been further validated using a literature‐based data set showing, even in this case, excellent performances. Finally, the literature‐based data set allowed us to improve the performances of the proposed approach in the field of large‐scale roughness. Efficiency tests indicate that the new equations can better reproduce the flow velocity in river reach where conventional flow resistance equations are not able to explain the entire dissipative process.
On the Field Estimation of Moisture Content Using Electrical Geophysics: The Impact of Petrophysical Model Uncertainty
Authors: Tso Chak‐Hau Michael , Kuras Oliver , Binley Andrew 
Published: August 2019

AbstractThe spatiotemporal distribution of pore water in the vadose zone can have a critical control on many processes in the near‐surface Earth, such as the onset of landslides, crop yield, groundwater recharge, and runoff generation. Electrical geophysics has been widely used to monitor the moisture content (θ) distribution in the vadose zone at field sites, and often resistivity (ρ) or conductivity (σ) is converted to moisture contents through petrophysical relationships (e.g., Archie's law). Though both the petrophysical relationships (i.e., choices of appropriate model and parameterization) and the derived moisture content are known to be subject to uncertainty, they are commonly treated as exact and error‐free. This study examines the impact of uncertain petrophysical relationships on the moisture content estimates derived from electrical geophysics. We show from a collection of data from multiple core samples that significant variability in the θ(ρ) relationship can exist. Using rules of error propagation, we demonstrate the combined effect of inversion and uncertain petrophysical parameterization on moisture content estimates and derive their uncertainty bounds. Through investigation of a water injection experiment, we observe that the petrophysical uncertainty yields a large range of estimated total moisture volume within the water plume. The estimates of changes in water volume, however, generally agree within (large) uncertainty bounds. Our results caution against solely relying on electrical geophysics to estimate moisture content in the field. The uncertainty propagation approach is transferrable to other field studies of moisture content estimation.
Water Vapor Sorption Properties of Illinois Shales Under Dynamic Water Vapor Conditions: Experimentation and Modeling
Authors: Sang Guijie , Liu Shimin , Elsworth Derek 
Published: August 2019

AbstractWater vapor adsorption/desorption isotherms are measured on five shales from Illinois basin by dynamic vapor sorption method. The experimental adsorption data are modeled by the Guggenheim, Anderson, and De Boer model and the Freundlich model over the entire range of measured relative humidity (Rh) values (0–0.95). Modeling results show that shale hydration is controlled by surface chemistry at low Rh through a strong intermolecular bonding, while is mainly influenced by the pore structure at high Rh (>0.9) through capillary condensation. This is consistent with the progressive decrease of isosteric heat of adsorption with water content, obtained by the Clausius‐Clapeyron equation. Exceptionally, for the one shale containing 8.6% montmorillonite, mesopore condensation only accounts for 33% of the measured water adsorption even at Rh ~0.95 due to the limited external pores and the important role of clay swelling. The specific surface area defined by Guggenheim, Anderson, and De Boer analysis as available for water adsorption is larger than that available for low‐pressure N2 adsorption due to the complex surface chemistry. The one shale rich in expansive montmorillonite and with a large interlayer capacity for water but inaccessible to N2 molecules conditions this result. Among the other four shales, one with high kerogen content behaves the highest water adsorption, possibly due to the high content of oxygen‐containing functional groups and the potentially high pore volume of kerogen. These findings contribute to a better understanding of water storage and transport behavior in shales and impact behavior relevant to structures and reservoirs founded in such media.
CCT α is a novel biomarker for diagnosis of laryngeal squamous cell cancer
Authors: Yang Jingpu , Zhang Zhuping , Zhao Yin , Cheng Jinzhang , Zhao Chang , Wang Zonggui 
Published: August 2019

AbstractCholine phosphate-based delivery systems can target the acidic tumor microenvironment. In this study, we set out to evaluate the diagnostic value of Choline phosphate cytidylyltransferase-α (CCTα) in laryngeal squamous cell cancer (LSCC). The expression of CCTα was detected using immunohistochemistry in 50 LSCC patients’ tissues and 16 vocal polyps as control group. Then, clinical data was collected and we used receiver operating characteristic curve (ROC) to estimate the potential of CCTα as diagnostic biomarker. We found CCTα levels to be significantly high in the tissues derived from LSCC patients, (p < 0.001). Further, we observed a positive correlation of CCTα with tumor size (p < 0.001), TNM stage (p < 0.001), lymph node metastasis (p < 0.001) as well as the grade of LSCC malignancy (p < 0.001). Furthermore, AUC was determined to be 0.939 by ROC, and the optimal cutoff value 3.100, with 76.0% sensitivity and 100% specificity. We also found an epigenetic basis of CCTα over-expression in LSCC tissues with significantly reduced methylation of CCTα in LSCC tissues, compared to vocal polyps (p < 0.001). These results support epigenetically-induced over-expression of CCTα as a potential diagnostic marker for LSCC.