bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reviu Implementasi Thorcon Molten Salt Reactor di Indonesia
Authors: Lumbanraja Sahala Maruli , Liun Edwaren 
Published: February 2019

REVIU IMPLEMENTASI THORCON MOLTEN SALT REACTOR DI INDONESIA. Thorcon Molten Salt Reactor (Thorcon MSR) merupakan jenis PLTN generasi ke-4 yang dirancang oleh Martingle Inc. Amerika Serikat. PLTN ini berbahan bakar, dan berpendingin garam cair , beroperasi pada temperatur tinggi dan tekanannya mendekati tekanan atmosfir. PLTN ini berdaya 1000 MWe yang dihasilkan oleh 4 modul dengan daya masing-masing 250 MWe. Makalah ini bertujuan untuk menguraikan dan memberi gambaran tentang kelayakan ThorCon MSR kepada pemangku kepentingan ketika akan diimplementasikan di Indonesia. Metodologi yang digunakan adalah mempelajari berbagai pustaka tentang teknologi Thorcon, ketersediaan SDM, partisipasi nasional dan regulasinya, serta dilakukan dengan analisis SWOT (Strength, Weaknesses, Opportunities, Threats). Jenis PLTN ini layak diimplementasikan dalam jangka panjang di Indonesia karena mempunyai aspek keselamatan tinggi, dan mudah dikonstruksi tetapi berbagai kendala masih perlu diselesaikan seperti status teknologi masih desain konsep, SDM belum tersedia, dan belum mendapat sertifikasi dari lembaga yang berwenang.
Spesifikasi, Kode dan Standar Baja Nasional dan Potensinya untuk Mendukung Program PLTN Tipe LWR di Indonesia
Authors: Dewi Dharu , Sriyana Sriyana 
Published: February 2019

SPESIFIKASI, KODE DAN STANDAR BAJA NASIONAL DAN POTENSINYA UNTUK MENDUKUNG PROGRAM PLTN TIPE LWR DI INDONESIA. Spesifikasi, kode dan standar baja nasional sangat penting diidentifkasi agar dapat dicocokkan atau dibandingkan dengan spesifikasi, kode dan standar internasional untuk komponen PLTN sehingga industri baja diharapkan dapat berpartisipasi dalam pembangunan Pembangkit Listrik Tenaga Nuklir (PLTN). Spesifikasi kode dan standar baja mengacu pada ASTM, ASME, AISC dan lain - lain. Tujuan studi ini adalah mengidentifikasi spesifikasi, kode dan standar baja yang dimiliki industri nasional dan kemudian dicocokkan dengan spesifikasi, kode dan standar baja sesuai standar internasional untuk PLTN. Metodologi penelitian adalah kajian literatur, pengiriman kuesioner, survei dan kunjungan teknis ke industri baja. Disimpulkan bahwa baja struktur pada dasarnya memenuhi persyaratan untuk konstruksi PLTN.Kata kunci: spesifikasi, kode, standar, baja, industriSPECIFICATION, CODE AND STANDARD OF NATIONAL STEEL AND THE POTENCY TO SUPPORT THE NUCLEAR POWER PROGRAMME OF LWR TYPE IN INDONESIA. Specification, codes and standards are important to identify in order to be matched or compared to international specifications, codes and standards for NPP components so that the steel industry is expected to participate in the construction of Nuclear Power Plants (NPPs). The specifications, code and standards of steel refer to ASTM, ASME, AISC and others. The purpose of this study is to identify specifications, codes and steel standards owned by national industries and then compared it to international standards for nuclear power plants. The research methodology is literature review, questionnaire submission, surveys and technical visits to the steel industry. It was concluded that the structural steel basically meets the requirements for NPP construction.Keywords: specification, code, standard, steel, industry
Cociente emocional de los estudiantes de Administración y Gestión Comercial de una universidad privada
Authors: Rojas Samanez Lita Regina , Arias Chávez Dennis , Norabuena Figueroa Roger Pedro , Mescua Figueroa Augusto César , Palacios Garay Jessica Paola , Caurcel Cara María Jesús 
Published: February 2019

La investigación tiene como objetivo determinar la dimensión predominante del cociente emocional de los estudiantes de Administración y Gestión Comercial de una universidad peruana privada. La investigación es de tipo sustantiva y de diseño no experimental, de nivel descriptivo-explicativo y de corte transversal. El instrumento utilizado para evaluar la variable ha sido el cuestionario del cuadro de Cociente Emocional (CE) (Cooper y Sawaf, 1997), el cual está conformado por 262 preguntas aplicadas sobre una muestra de 86 estudiantes universitarios. Los resultados permitieron determinar que la dimensión “Valores y creencias” (B = 1.814) presenta mayor coeficiente y, por ende, aporta más al cociente emocional de los estudiantes analizados. Esta predominancia parte del resultado de la dimensión que presenta un odds ratio (Exp(B)) = 6.134, lo que evidencia que esta es una dimensión de riesgo, lo que llevaría a que un estudiante tenga 6.134 de veces de posibilidad de presentar niveles bajos de cociente emocional respecto a otro con niveles altos de cociente emocional por causa de la dimensión “Valores y creencias”.
The Analysis of Osteoblast Cell Number on Femur Fractures Provided Red Spinach Extract (Amaranthus tricolor L.)
Authors: Nugroho Ferdian , Prasetyo Aris , Hasan Muhammad 
Published: February 2019

Bone fracture is a musculoskeletal injury with a high incidence rate. The healing process of the fracture can be inhibited by oxidative stress, which occurs due to Reactive Oxygen Species (ROS) that exceeds the antioxidant capacity in the body that neutralizes it. Antioxidants that have red spinach have the potential to suppress the level of oxidative stress. This study aims to determine the effect of red spinach ethanol extract on the healing process of fracture in male Wistar rats through osteoblast cell count. A sample of 30 male Wistar rats was divided into five groups; negative control group, positive control group, and three groups of red spinach ethanol treatment with doses of 35.4 mg / 150 g body weight (BW), 70.8 mg / 150 gBW, and 141.6 mg / 150gBW induced fracture, splinted, then treated for one week. One Way Anova test results showed a significance of 0.000 (p <0.05) in which there was a significant difference in the osteoblast level between the treatment group and the control group. The result of LSD test between P1 group and P3 group showed significantly different result where the increase of osteoblast cell number was in line with the increase of the dose of red spinach ethanol extract. The conclusion is that red spinach ethanol extract has a positive impact during the fracture healing process with osteoblast cell number parameters.
Keywords: Red spinach ethanolic extract, fracture healing process, osteoblast, oxidative stress
Antibiotic Sensitivity Test on Staphylococcus Aureus Detected in Sputum of Patients with Pneumonia Treated in Hospitals
Authors: Agustina Dini , Mufida Diana Chusna , A.S. Hanifa Rizki , Dharmawan Dion Krismashogi 
Published: February 2019

Pneumonia is a respiratory tract infection that attacks the pulmonary parenchyma. This disease can be caused by bacteria, one of which is Staphylococcus aureus. Antibiotics have an important role to play in reducing the morbidity and mortality incidence of pneumonia, but currently, the incidence of resistance antibiotics is increased. The purpose of this study was to determine the sensitivity of antibiotics Staphylococcus aureus in pneumatic sputum patients. The design of this study was observational descriptive, using sputum samples from pneumonia patients in Subandi and Paru Jember hospitals in November to December 2018. The identification of bacteria in sputum was continued by testing the sensitivity of bacteria to antibiotics. The antibiotics used in this study were chloramphenicol, gentamicin, amikacin, levofloxacin, ampicillin-sulbactam, cotrimoxazole, and ciprofloxacin — data obtained in the frequency distribution table. Of the ten sputum that was successfully cultured, four Gram-negative bacilli bacteria and six Gram-positive coccus bacteria were obtained. The results approved the six Gram-positive coccus bacteria, detected as Staphylococcus aureus. The antibiotic resistance of Staphylococcus aureus to ampicillin-sulbactam was high.
Keywords: antibiotic sensitivity, bacteria, pneumonia
Intra-operative red blood cell transfusion and mortality after cardiac surgery
Authors: Vlot Eline A , Verwijmeren Lisa , de Garde Ewoudt M.W. Van , Kloppenburg Geoffrey T.L. , Dongen Eric P.A. Van , Noordzij Peter G. 
Published: February 2019

Abstract
Background

Anemia in cardiac surgery patients has been associated with poor outcomes. Transfusion of red blood cells during surgery is common practice for perioperative anemia, but may come with risks. Little is known about the association between intra-operative transfusion and mortality in patients undergoing cardiac surgery.

Methods

Single centre historical cohort study in 2933 adult patients undergoing coronary surgery with or without aortic valve replacement from June 2011 until September 2014. To estimate the odds ratio for mortality in patients receiving intra-operative transfusion, a propensity score based logistic regression analysis was performed.

Results

Intra-operative transfusion was associated with a more than three-fold increased risk of 30-day mortality. Patients in the highest quartile of probability of transfusion were older (age 75 vs 66; P<0.001), had a higher EuroSCORE (6 vs 3; P<0.001), had lower preoperative hemoglobin levels (7.6 vs 8.9 mmol/l; P<0.001), had combined surgery more often (CABG + AVR in 33.4% of cases vs 6.6% (P<0.001) and a longer duration of surgery (224 vs 188 minutes; P<0.001). The association between intra-operative transfusion and mortality persisted after adjustment for these risk factors (adjusted OR 2.6; P=0.007).

Conclusions

Intra-operative transfusion of red blood cells was found to be associated with increased mortality in adults undergoing coronary surgery. Preoperative patient optimization may improve perioperative outcomes by reducing the likelihood of requiring transfusion and thus its associated risk.
Pilot-scale study to investigate the impact of rotating belt filter upstream of a MBR for nitrogen removal
Authors: Razafimanantsoa V. A. , Adyasari D. , Sahu A. K. , Rusten B. , Bilstad T. , Ydstebø L. 
Published: February 2019

Abstract
The goal of this study was to investigate what kind of impact the removal of particulate organic matter with 33μm rotating belt filter (RBF) (as a primary treatment) will have on the membrane bioreactor (MBR) performance. Two small MBR pilot plants were operated in parallel, where one train treated 2mm screened municipal wastewater (Train A) and the other train treated wastewater that had passed through a RBF with a 33μm filter cloth (Train B). The RBF was operated without a filter mat on the belt. About one third of the organic matter was removed by the fine mesh filter. The assessment of the overall performance showed that the two pilot plants achieved approximately the same removal efficiencies with regard to total suspended solids (TSS), chemical oxygen demand (COD), total phosphorus and total nitrogen. It was also observed that the system with 33μm RBF as a primary treatment produced more sludge, which could be used for biogas production, and required about 30% less aeration downstream. Transmembrane pressure was significantly lower for the train receiving 33μm primary treated wastewater compared to the control receiving 2mm screened wastewater.
Gedunin, A Neem Limonoid in Combination with Epalrestat Inhibits Cancer Hallmarks by Attenuating Aldose Reductase-Driven Oncogenic Signaling in SCC131 Oral Cancer Cells
Authors: Tanagala Kranthi K.K. , Baba Abdul B. , Kowshik Jaganathan , Reddy Geereddy B. , Nagini Siddavaram 
Published: February 2019

Background and Objectives: Aldose Reductase (AR), a polyol pathway enzyme that mediates
diabetic complications is implicated in tumour development and progression. This study was undertaken to
determine whether gedunin, a neem limonoid prevents the hallmarks of cancer by inhibiting AR and the associated
downstream PI3K/Akt/mTOR/ERK/NF-κB signalling axis in the SCC131 oral cancer cell line.

Methods:
The expression of AR and key molecules involved in cell proliferation, apoptosis, autophagy, invasion
and angiogenesis was analysed by qRT-PCR, and immunoblotting. ROS generation and cell cycle were
analysed by FACS. Alamar blue assay and scratch assay were used to evaluate cell proliferation and migration
in the endothelial cell line Eahy926.

Results:
Gedunin and the AR inhibitor epalrestat inhibited AR expression and ROS generation. Cell cycle arrest
at G1/S was associated with cell death by autophagy with subsequent switch over to apoptosis. Furthermore,
hypoxia-induced cell migration was inhibited in Eahy926 cells with downregulation of pro-invasive and proangiogenic
proteins in SCC131 as well as Eahy926 cells. Co-inactivation of Akt and ERK was coupled with
abrogation of IKK/NF-κB signaling. However, the combination of gedunin and epalrestat was more effective
than single agents.

Conclusion:
Inhibition of AR-mediated ROS signalling may be a key mechanism by which gedunin and epalrestat
exert their anticancer effects. Our results provide compelling evidence that the combination of gedunin
and epalrestat modulates expression of key oncogenic signalling kinases and transcription factors primarily by
influencing phosphorylation and subcellular localisation. AR inhibitors such as gedunin and epalrestat are novel
candidate agents for cancer prevention and therapy.
Current Review on Plant based Pharmaceutical Excipients
Authors: Pal Rashmi Saxena , Pal Yogendra , Wal Ankita , Wal Pranay 
Published: February 2019

Background:
Plants act as a major source of medicines and are used to formulate various pharmaceutical preparations. Apart from this, they act as excellent pharmaceutical aids as well as excipients.

Objective:
An effort has been made for the complete study of plants under different categories of plant-based thickeners, emulsifiers, suspenders, binders, etc.

Materials and Methods:
The herbs were differentiated on the basis of their role as flavoring, sweetening, colouring, gelling, thickening, emulsifying, suspending and binding agents.

Results:
The use of natural excipients to impart the goodness of natural bioactive agents has been hampered by synthetic materials. However, advantages offered by these natural excipients are enormous as being non-toxic, affordable and easily available. The activity of the excipients partly determines the quality of medicines.

Conclusion:
The herbal excipients act better in many ways when compared to their synthetic substitutes.
Effect of Etidronate and Ibandronate on Cytosolic Ca2+ in HT29 and Parasite Cell Line from Echinococcus Granulosus sensu lato
Authors: Ferrulli Mariana , Rojo Fernando Gabriel Pérez , Herrera Lilian Andrea Granada , Maglioco Andrea , Roldán Emilio AJ , Fuchs Alicia Graciela 
Published: February 2019

Background:
The bisphosphonates are synthetic analogs of pyrophosphate in which two phosphates are connected through carbon instead of oxygen. They are approved compounds for the treatment of hypercalcemia, bone diseases and they have been proposed to treat infectious diseases. Bisphosphonates’ main mechanisms of action are on calcium metabolism, inhibition of protein prenylation and on ATP synthesis. In a previous work, the antiparasitic activity of bisphosphonates on a cell line from Echinococcus granulosus, sensu lato protoscoleces, 30 µM etidronate and ibandronate have antiproliferative activity after 72 h of incubation, decreasing intracellular ATP and only etidronate increased intracellular total calcium concentration.

Objective:
This work studied the effect of etidronate and ibandronate on cytoplasmic ionic calcium concentration in parasitic cell line and in HT29, cell line from human colon adenocarcinoma.

Methods:
Ionic calcium was measured by spectrofluorometric, labeling cells with Fluo-4AM. Cells were suspended in Na+ or K+ rich buffer and two calcium salts were used Cl- or Gluc-, anion permeable and impermeable, respectively.

Results:

Remarkable differences between cell lines were shown with the effect of bisphosphonates on intracellular ionic calcium concentration in hyperpolarized cells and these differences were smoothed on depolarized cells, in spite of the similar cellular response to calcium salts in absence of bisphosphonates.

Conclusion:
The bisphosphonates, mainly etidronate, decreased intracellular ionic calcium on parasitic cells explaining other aspects of their antiproliferative effect. Results suggested that other mechanism, such as Cl- and Na+ interchange are differentially affected by bisphosphonates, depending on cell line origin.
Category Classification of the Training Set Combined with Sentence Multiplication for Semantic Data Extraction Using GENI Algorithm
Authors: Shanmugam Saravana Kumar Coimbatore , Rajendran Santhosh , Padmanabhan Amudhavalli , Chellan Kalaiarasan 
Published: February 2019

Background:
Increase in the internet data has increased the priority in the data extraction accuracy.
Accuracy here lies with what data the user has requested for and what has been retrieved. The same large
data sets that need to be analyzed make the required information retrieval a challenging task.

Objective:
To propose a new algorithm in an improved way than the traditional methods to classify the category
or group to which each training sentence belongs.

Method:
Identifying the category to which the input sentence belongs is achieved by analyzing the Noun
and Verb of each training sentence. NLP is applied to each training sentence and the group or category classification
is achieved using the proposed GENI algorithm so that the classifier is trained efficiently to extract
the user requested information.

Results:
The input sentences are transformed into a data table by applying GENI algorithm for group categorization.
Plotting the graph in R tool, the accuracy of the group extracted by the Classifier involving GENI
approach is higher than that of Naive Bayes & Decision Trees.

Conclusion:
It remains a challenging task to extract the user-requested data, when the user query is complex.
Existing techniques are based more on the fixed attributes, and when we move with respect to the fixed
attributes, it becomes too complex or impossible for us to determine the common group from the base sentence.
Existing techniques are more suitable to a smaller dataset, whereas the proposed GENI algorithm does
not hold any restrictions for the Group categorization of larger data sets.
FAKTOR DOMINAN PREMENSTRUAL SYNDROME PADA MAHASISWI (STUDI PADA MAHASISWI FAKULTAS KESEHATAN MASYARAKAT DAN DEPARTEMEN ARSITEKTUR FAKULTAS TEKNIK, UNIVERSITAS INDONESIA)
Authors: Ilmi Ayatun Fil , Utari Diah Mulyawati 
Published: February 2019

Latar belakang. Premenstrual syndrome (PMS) merupakan kumpulan gejala fisik, psikologis, dan emosi, yang dialami wanita pada 7-14 hari sebelum mentruasi akibat perubahan hormonal yang berhubungan dengan siklus ovulasi. Gejala yang sering dirasakan adalah perubahan mood, nyeri sendi atau otot, dan nyeri perut. PMS pada remaja putri dapat mengganggu aktivitas dan konsentrasi belajar. Tujuan. Tujuan penelitian ini adalah mengetahui faktor dominan yang berhubungan dengan gejala premenstrual syndrome pada mahasiswi Universitas Indonesia. Metode. Desain studi dalam penelitian ini adalah cross sectional dengan consecutive sampling technique. Sampel penelitian berjumlah 130 mahasiswi yang berasal dari S1 reguler Fakultas Kesehatan Masyarakat dan Departemen Arsitek Fakultas Teknik angkatan 2015/2016. Variabel yang diteliti terdiri dari gejala premenstrual syndrome, tingkat stres, aktivitas fisik, asupan gizi mikro (piridoksin, vitamin D, kalsium dan magnesium), pola tidur, dan status gizi. Hasil. Hasil penelitian menunjukan sebanyak 36,9 persen mahasiswi mengalami gejala PMS sedang hingga berat. Terdapat hubungan yang signifikan antara tingkat stres (p=0,001), asupan piridoksin (p=0,003), asupan magnesium (p=0,044), pola tidur (p=0,006) dengan gejala premenstrual syndrome. Faktor yang paling dominan mempengaruhi gejala PMS adalah pola tidur (OR=3,580). Mahasiswi dengan pola tidur yang buruk berisiko mengalami premenstrual syndrome 3,580 kali lebih tinggi dibandingkan dengan mahasiswi yang memiliki pola tidur yang baik. Kesimpulan. Disarankan pihak kampus dapat memberikan promosi kesehatan yang berhubungan dengan gejala premenstrual syndrome, pentingnya pola tidur yang baik dan cukup, pengendalian stres, dan pentingnya asupan gizi mikro.
PROJETO CRAZY STORIES: A INTERDISCIPLINARIDADE NO ENSINO DE INGLÊS COMO LÍNGUA ADICIONAL
Authors: Vanzin de Gasperi Fernando , Welp Anamaria 
Published: February 2019

Este artigo relata a experiência com o desenvolvimento de um projeto pedagógico durante o estágio de docência em língua inglesa. O objetivo foi elaborar e aplicar uma sequência didática para o ensino de inglês como língua adicional em uma turma de sexto ano de uma escola da rede pública de educação básica, utilizando-se de um projeto interdisciplinar com o componente curricular artes. Os projetos interdisciplinares têm sido apontados como práticas desejáveis e eficientes para o desenvolvimento de conhecimento relevante para os alunos por aproximar o conteúdo a sua realidade. A sequência didática foi planejada dentro da abordagem de projetos de trabalho, uma proposta colaborativamente construída e organizada com a participação de professores e alunos. Dessa forma, o projeto foi planejado previamente, mas construído aula a aula, culminando na encenação de um texto teatral ,escrito pelos alunos, e em um livro contendo as histórias encenadas. O projeto foi desenvolvido em 11 aulas de inglês e três aulas de artes. Este artigo apresenta o desenvolvimento do projeto e, com base nos estudos sobre interdisciplinaridade e educação por projetos, apresenta reflexões sobre seu desenvolvimento.
Palavras-chave: língua adicional, educação por projetos, interdisciplinaridade, sequência didática.
O PRECONCEITO RACIAL OITOCENTISTA NA PRIMEIRA OBRA NATURALISTA DE ALUÍZIO AZEVEDO
Authors: Ferreira Gileno Alves , Chaves Cleide De Lima 
Published: February 2019

RESUMO:
O trabalho aqui apresentado objetiva investigar o preconceito racial da sociedade maranhense sobre o personagem principal, Dr. Raimundo, na obra O mulato do abolicionista Aluísio Azevedo. Outrossim, estudar o uso da linguagem em que, preconceituosamente, no século XIX, se submetiam, ao sabor do cientificismo, negros e descendentes. A partir da literatura historiográfica e antropológica sobre o tema do racismo brasileiro, bem como a análise da linguagem empregada no romance, buscou-se analisar tal ocorrência na composição naturalista. Na produção azevediana, que opera eminentemente como crítica social, averiguar determinada prática que perpassa gerações no Brasil e no mundo.
POÉTICAS PERIFÉRICAS E AS INSCRIÇÕES DA NEGRITUDE NO BRASIL
Authors: Fonseca Silvana Carvalho da 
Published: February 2019

O presente artigo tem como objetivo buscar nas inscrições periféricas do movimento hip hop no Brasil, possíveis reelaborações das identidades negras, a patir da recosntrução da memória coletiva afrodiaspórica e denúncia contra o racismo brasileiro, que organizou no âmbito de todas as relações sociais a falsa democratização racial através de um discurso de nação multiétinica que apagou a comunidade negra sistematicamente do cenário nacional.