bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reavaliação das condições de cristalização de granitos alcalinos ediacaranos dos domínios Rio Piranhas-Seridó e São José do Campestre, Província Borborema, NE-Brasil
Authors: Dalan Clarissa De Aguiar , Vilalva Frederico Castro Jobim , Nascimento Marcos Antônio Leite 
Published: May 2019

As condições de cristalização (P, T, ƒO2) de granitos alcalinos (tipo-A) nos domínios Rio Piranhas-Seridó e São José do Campestre (NE da Província Borborema) foram reavaliadas a partir da aplicação simultânea de múltiplos geobaromômetros e geotermômetros e modelagens de cristalização. Os corpos estudados são os plútons Caxexa, Serra do Algodão, Serra do Boqueirão, Olho D’Água, Japi e Serra Negra do Norte e o stock Flores. Os resultados mostram pressões de alojamento entre 3,0 e 3,7 kbar (~11–14 km em profundidade), à exceção do plúton Japi, com pressões médias de 5,3 kbar (~20 km). Os modelamentos resultam em temperaturas de liquidus entre 885–917 e 818ºC para o stock Flores, e solidus entre 660 e 700ºC. Egirina-augita, magnésio-ferri-hornblenda e biotita cristalizam-se entre 813–822, 728–751 e 750–789ºC, respectivamente. Entre os acessórios, o geotermômetro Zr-em-titanita retorna temperaturas da ordem de 780ºC (máximas de 830ºC) para o plúton Caxexa. A cristalização ocorreu sob condições essencialmente oxidantes para a maioria dos plútons (+1,0 < ΔQFM < +2,1), à exceção do stock Flores, formado sob condições levemente mais reduzidas (ΔQFM ≈ 0,0). Os plútons associados a zonas de cisalhamento regionais são mais enriquecidos em álcalis e, em média, mais profundos, reforçando o papel do controle estrutural na colocação e no contraste químico entre os granitos. As novas estimativas são mais acuradas e contribuem para o melhor entendimento da evolução do magmatismo granítico alcalino na porção setentrional da Província Borborema.
Heart Rate Reserve in Fontan Patients: Chronotropic Incompetence or Hemodynamic Limitation?
Authors: Claessen Guido , La Gerche Andre , Van De Bruaene Alexander , Claeys Mathias , Willems Rik , Dymarkowski Steven , Bogaert Jan , Claus Piet , Budts Werner , Heidbuchel Hein , Gewillig Marc 
Published: May 2019

Background

Patients with a Fontan circulation achieve lower peak heart rates (
HR
) during exercise. Whether this impaired chronotropic response reflects pathology of the sinoatrial node or is a consequence of altered cardiac hemodynamics is uncertain. We evaluated the adequacy of
HR
acceleration throughout exercise relative to metabolic demand and cardiac output in patients with a Fontan circulation relative to healthy controls.

Methods and Results

Thirty subjects (20 healthy controls and 10 Fontan patients) underwent cardiac magnetic resonance imaging with simultaneous invasive pressure recording via a pulmonary and radial artery catheter during supine bicycle exercise to near maximal exertion. Adequacy of cardiac index, stroke volume, and
HR
reserve was assessed by determining the exercise‐induced increase (∆) in cardiac index, stroke volume, and
HR
relative to the increase in oxygen consumption (
VO
2
).
HR
reserve was lower in Fontan patients compared with controls (71±21 versus 92±15 bpm;
P
=0.001). In contrast, increases in
HR
relative to workload and
VO
2
were higher than in controls. The change in cardiac index relative to the change in
VO
2
(∆cardiac index/∆
VO
2
) was similar between groups, but Fontan patients had increased ∆
HR
/∆
VO
2
and reduced ∆ stroke volume/∆
VO
2
compared with controls. There was an early and marked reduction in stroke volume during exercise in Fontan patients corresponding with a plateau in cardiac output at a low peak
HR
.

Conclusions

In Fontan patients, the chronotropic response is appropriate relative to exercise intensity, implying normal sinoatrial function. However, premature reductions in ventricular filling and stroke volume cause an early plateau in cardiac output beyond which further increases in
HR
would be physiologically implausible. Thus, abnormal cardiac filling rather than sinoatrial node dysfunction explains the diminished
HR
reserve in Fontan patients.
Prospective Comparison of a Percutaneous Ventricular Assist Device and Venoarterial Extracorporeal Membrane Oxygenation for Patients With Cardiogenic Shock Following Acute Myocardial Infarction
Authors: Garan A. Reshad , Takeda Koji , Salna Michael , Vandenberge John , Doshi Darshan , Karmpaliotis Dimitri , Kirtane Ajay J. , Takayama Hiroo , Kurlansky Paul 
Published: May 2019

Background

Cardiogenic shock (
CS
) following acute myocardial infarction (
AMI
) portends a poor prognosis. Both venoarterial extracorporeal membrane oxygenation (
VA
‐
ECMO
) and a percutaneous ventricular assist device (
pVAD
) provide hemodynamic support for patients with
CS,
but little is known about the best device for this population. We sought to compare outcomes of
AMI
patients treated with these devices.

Methods and Results

Consecutive patients with
CS
following
AMI
from April 2015 to March 2017 were enrolled prospectively if they received either device for
AMI
‐related
CS
. If patients received both devices, they were analyzed according to the first used. The primary outcome was all‐cause mortality. In total, 51 patients received
VA
‐
ECMO
or
pVAD
following
AMI
; 20 received
VA
‐
ECMO,
and 31 received
pVAD
. The mean age was 62.1±10.1 years, and 39 (76.5%) were men. Twenty‐four (47.1%) patients were ultimately supported by both devices simultaneously (20
pVAD
‐first, 4
VA
‐
ECMO
‐first). Patients treated with
pVAD
or
VA
‐
ECMO
were similar in baseline characteristics at initial device insertion except that the latter were on more vasopressors and were more likely to have an intra‐aortic balloon pump. Seventeen (33.3%) had recent cardiopulmonary resuscitation, mean lactate was 4.86±3.96 mmol/L, and mean cardiac index was 1.70±0.42 L/min per m
2
. Of the 28 (54.9%) patients surviving to discharge, 11 had received
VA
‐
ECMO
first and 17 had
pVAD
first (
P
=0.99). Survival at 1 and 2 years did not differ significantly between device groups (
P
=0.42).

Conclusions

Following
AMI
‐related
CS
,
pVAD
‐ and
VA
‐
ECMO
‐treated patients had similar outcomes. The use of both devices simultaneously was common, with almost half of patients in persistent
CS
after first device deployment.
Australocorinae, a new subfamily of Geocoridae (Hemiptera: Heteroptera: Lygaeoidea) from Australia, with descriptions of a new genus and two new species
Authors: MALIPATIL M. B. 
Published: May 2019

Australocorinae subfam. nov., a new subfamily of family Geocoridae, is erected for Australocoris gen. nov. containing three species, A. kurandae Kirkaldy, 1908, A. fuscomaculatus sp. nov., and A. monticolus sp. nov., all from Queensland, Australia. Australocoris monticolus has been collected only from northern Queensland, near Julatten north of Cairns to Bellenden Ker Range area, and mostly at higher altitudes 800 to 1560 m; A. kurandae from usually lower altitudes of northern Queensland; and A. fuscomaculatus is known from southern Queensland. The affinities of the subfamily are discussed in relation to other subfamilies of Geocoridae as well as other related families of Lygaeoidea. Geocoridae is redefined to contain this new subfamily. A key to species is provided.
Contributing Factors to Spatiotemporal Variations of Outgoing Longwave Radiation (OLR) in the Tropics
Authors: Fajary Faiz R. , Hadi Tri W. , Yoden Shigeo 
Published: May 2019

Abstract
Factors governing spatiotemporal variations of the daily outgoing longwave radiation (OLR) are studied using 35-yr (1979–2013) data records by employing multiple linear regression, wavelet transforms, and bandpass filtering methods. From the regression coefficients of nine predictors and the explained variances, we found that the largest contributions to OLR variability are associated with the Madden–Julian oscillation and El Niño–Southern Oscillation (ENSO). The ENSO signatures on OLR show dipole patterns over the Maritime Continent (MC) and Pacific regions with an extension to the Atlantic. Subsequently, the third significant contribution of the Indian Ocean dipole is confined to the Indian Ocean and Africa. Then, the solar cycle and stratospheric aerosols show mainly negative correlations, while a positive linear trend is observed mainly in the Northern Hemisphere. Lastly, factors associated with the stratospheric quasi-biennial oscillation (QBO) are the least significant contributor to OLR. In terms of oscillatory signals, time–longitude variations of the annual cycle (AC) show pairs of contrasting phases that characterize monsoon systems, in which the MC and Pacific regions are found to be in the same phase group. The most consistent AC signals are found to correspond with North and South American monsoons that respectively exhibit weakening and strengthening trends. Wavelet spectra and filtered OLR signals in intraseasonal oscillation, QBO, and ENSO frequency bands show an interdependent relationship that largely varies with time scale and longitudes.
The most mentioned neuroimaging articles in online media: a bibliometric analysis of the top 100 articles with the highest Altmetric Attention Scores
Authors: Kim Eun Soo , Yoon Dae Young , Kim Hye Jeong , Lee Kwanseop , Kim Yerim , Bae Jong Seok , Lee Ju-Hun 
Published: May 2019

Background Alternative metrics (Altmetrics) based on mentions in online media is a new tool that can help identify articles that have the most influence on diverse public audiences. Purpose To determine the 100 most mentioned articles in the field of neuroimaging and to analyze their characteristics. Material and Methods We selected the 668 journals that were considered to potentially publish neuroimaging articles. Using the Altmetric.com search tool, we identified the 100 most mentioned neuroimaging articles based on the highest Altmetric Attention Scores (AAS) within selected journals. Each article was evaluated for several characteristics including AAS, number of citations, journal title, impact factor of journal, year of publication, authorship, country, type of document, disease entity, and imaging technique. Results The AAS for the top 100 articles were in the range of 145–1467. Frontiers in Human Neuroscience published the largest number of articles (n = 9), followed by Radiology (n = 8) and Neurology (n = 8). All articles were published during 2006–2018, with 56% of articles being published in 2016–2018. The majority of articles originated from the United States (n = 56), were original articles (n = 81), covered normal population (n = 67), and used functional magnetic resonance imaging (n = 56). Sasaki was the most prolific, authoring three of the most mentioned neuroimaging articles. Conclusion This study presents a detailed list of the 100 most mentioned neuroimaging articles in online media, thus providing useful information on the dissemination of neuroimaging research to the general public.
Are low-dose CT scans a satisfactory substitute for stereoradiographs for migration studies? A preclinical test of low-dose CT scanning protocols and their application in a pilot patient
Authors: Eriksson Thomas , Maguire Gerald Q , Noz Marilyn E , Zeleznik Michael P , Olivecrona Henrik , Shalabi Adel , Hänni Mari 
Published: May 2019

Background Computed tomography (CT) has the potential to acquire the data needed for migration studies of orthopedic joint implants of patients who have had tantalum beads implanted at the time of joint replacement surgery. This can be accomplished with the same precision as radiostereometric analysis (RSA). Switching to CT would increase availability without the need for the specific facilities required for RSA. However, higher effective dose is a concern. Purpose To investigate if migration measurements can be done with CT with an accuracy and effective dose comparable to that of conventional RSA. Material and Methods Fourteen scanning protocols were tested in a hip phantom that incorporated tantalum beads and an uncemented femoral stem. The protocols were graded for clinical practice according to the three parameters of image quality, effective dose, and robustness of numerical data. After grading, the two protocols that graded best overall were applied to a pilot patient. Results All protocols produced scans in which the numerical data were sufficient for a migration analysis at least as precise as would be expected using RSA. A protocol with an effective dose of 0.70 mSv was shown to be applicable in a pilot patient. Conclusion Low-dose CT scans with an effective dose comparable to a set of routine plain radiographs can be used for precise migration measurements.
Computer-assisted prediction of atherosclerotic intimal thickness based on weight of adrenal gland, interleukin-6 concentration, and neural networks
Authors: Meng Ling-bing , Zou Yang-fan , Shan Meng-jie , Zhang Meng , Qi Ruo-mei , Yu Ze-mou , Guo Peng , Zheng Qian-wei , Gong Tao 
Published: May 2019

Objective Atherosclerosis (AS) is the main pathological basis of ischemic cardio-cerebrovascular diseases, and the intimal thickness (IT) of large arteries is regarded as a powerful evaluation indicator for AS. We established an effective neural network model for automatic prediction of the IT and analyzed the high-risk warning indicators of IT. Methods The weight of the left adrenal (WLA) was evaluated. The serum interleukin-6 (IL-6) concentration was measured by enzyme-linked immunosorbent assay. The statistical methods included neural network modeling, a cubic spline interpolation algorithm, Spearman’s rho test, and linear fit. Results Thirty-seven rabbits were classified into a control group (n = 11), high-fat diet group (n = 13), and high-fat diet plus chronic stress group (n = 13). The neural network model was successfully established and verified by comparing the predicted IT with the actual IT. The high-risk warning indicator of IT was identified as follows: 0.445 g < WLA < 0.610 g and 60 ng/L< IL-6 < 80 ng/L. Conclusions The neural network model based on WLA and IL-6 could predict the IT of AS. When 0.445 g < WLA < 0.610 g and 60 ng/L < IL-6 < 80 ng/L, the risk to developing AS is very high.
CHA2DS2-Vasc score and CHA2DS2-Vasc-HS score are poor predictors of in-stent restenosis among patients with coronary drug-eluting stents
Authors: Zhao Sheng Gang , Xu Jian Jiang , Tao Zhen Hao , Jin Lei , Liu Qin , Zheng Wen Yue , Jiang Li Qin , Wang Ning Fu 
Published: May 2019

Objective To evaluate the ability of two scoring systems (CHA2DS2-VASc score and CHA2DS2-VASc+hyperlipidaemia+smoking [CHA2DS2-VASc-HS score]) to predict in-stent restenosis (ISR) among patients undergoing drug-eluting stent (DES) implantation. Methods This retrospective study enrolled patients who underwent coronary angiography to assess coronary artery disease severity secondary to a diagnosis of stable angina or acute coronary syndrome that subsequently underwent DES implantations. Demographic, clinical, angiographic and biochemical parameters were compared between those patients that experienced ISR and those that did not during the study follow-up period. Univariate and multivariate logistic regression analyses were used to evaluate associations between the baseline parameters, the two scoring systems and ISR risk. Results A total of 358 patients (non-ISR group n = 316; ISR group n = 42) participated in the study. Compared with the non-ISR group, more patients in the ISR group had diabetes mellitus and received stents with smaller diameters but longer lengths. There were no significant differences with regard the predictive ability for ISR of either the CHA2DS2-Vasc or the CHA2DS2-Vasc-HS scores. Multivariate logistic regression analyses demonstrated that stent diameter, follow-up duration and glycosylated haemoglobin were independent risk factors for ISR. Conclusions The CHA2DS2-Vasc and CHA2DS2-Vasc-HS scores did not predict ISR in patients after coronary DES placement.
Tumor blood supply may predict neoadjuvant chemotherapy response and survival in patients with gastric cancer
Authors: Ji Xiang , Yang Qiaoyun , Qin Hui , Zhou Jie , Liu Wenming 
Published: May 2019

Objectives We investigated the prognostic value of tumor blood supply in patients with advanced gastric cancer (GC) receiving neoadjuvant chemotherapy. Methods We retrospectively reviewed 53 patients with advanced GC treated with FLEEOX chemotherapy. The tumor computed tomography (CT) enhancement value was measured before chemotherapy (CT1; arterial phase CT–plain phase CT). The liver parenchyma CT enhancement value (CT2) was also measured using the same method, to eliminate individual differences. Tumor blood supply was defined as good or poor based on the median CT1/CT2 values. We evaluated the relationships between tumor blood supply and response to chemotherapy, clinicopathologic characteristics, and overall survival (OS). Results A good blood supply (GBS) was associated with significantly better clinical and pathological responses to chemotherapy than a poor blood supply (PBS). The 3-year OS was 65.8% for the entire cohort. Patients with a GBS had a significantly higher OS (78.57%) than those with a PBS (54.44%). Additionally, patients with Bormann type III GC had a better blood supply than those with type II GC. Conclusion Patients with advanced GC and a GBS are more likely to benefit from neoadjuvant chemotherapy than those with a PBS. Blood supply may thus be a predictor for chemotherapy response.
A web-based, branching logic questionnaire for the automated classification of migraine
Authors: Kaiser Eric A , Igdalova Aleksandra , Aguirre Geoffrey K , Cucchiara Brett 
Published: May 2019

Objective To identify migraineurs and headache-free individuals with an online questionnaire and automated analysis algorithm. Methods We created a branching-logic, web-based questionnaire – the Penn Online Evaluation of Migraine – to obtain standardized headache history from a previously studied cohort. Responses were analyzed with an automated algorithm to assign subjects to one of several categories based on ICHD-3 (beta) criteria. Following a pre-registered protocol, the primary outcome was sensitivity and specificity for assignment of headache-free, migraine without aura, and migraine with aura labels, as compared to a prior classification by neurologist interview. Results Of 118 subjects contacted, 90 (76%) completed the questionnaire; of these 31 were headache-free controls, 29 migraine without aura, and 30 migraine with aura. Mean age was 41 ± 6 years and 76% were female. There were no significant demographic differences between groups. The median time to complete the questionnaire was 2.5 minutes (IQR: 1.5–3.4 minutes). Sensitivity of the Penn Online Evaluation of Migraine tool was 42%, 59%, 70%, and 83%, and specificity was 100%, 84%, 93%, and 90% for headache-free controls, migraine without aura, migraine with aura, and migraine overall, respectively. Conclusions The Penn Online Evaluation of Migraine web-based questionnaire, and associated analysis routine, identifies headache-free and migraine subjects with good specificity. It may be useful for classifying subjects for large-scale research studies. Research study pre-registration: https://osf.io/sq9ef The following research study is a not a clinical trial.
The Effect of Ankle Bracing on Kinematics in Simulated Sprain and Drop Landings: A Double-Blind, Placebo-Controlled Study
Authors: Agres Alison N. , Chrysanthou Marios , Raffalt Peter C. 
Published: May 2019

Background: The efficacy of external ankle braces to protect against sudden inversion sprain has yet to be determined while taking into account the possible placebo effect of brace application. Purpose: To assess the protective effect of an external ankle brace on ankle kinematics during simulated inversion sprain and single-legged drop landings among individuals with a history of unilateral lateral ankle sprain. Hypothesis: The primary hypothesis was that active and placebo external braces would reduce inversion angle during simulated inversion sprain. Study Design: Controlled laboratory study. Methods: Sixteen participants with ankle instability and previous sprain performed single-legged drop landings and sudden inversion tilt perturbations. Kinematics of the affected limb were assessed in 3 conditions (active bracing, passive placebo bracing, and unbraced) across 2 measurement days. Participators and investigators were blinded to the brace type tested. The effect of bracing on kinematics was assessed with repeated measures analysis of variance with statistical parametric mapping, with post hoc tests performed for significant interactions. Results: Only active bracing reduced inversion angles during a sudden ankle inversion when compared with the unbraced condition. This reduction was apparent between 65 and 140 milliseconds after the initial fall. No significant differences in inversion angle were found between the passive placebo brace and unbraced conditions during sudden ankle inversion. Furthermore, no significant differences were found among all tested conditions in the sagittal plane kinematics at the knee and ankle. Conclusion: During an inversion sprain, only the actively protecting ankle brace limited inversion angles among participants. These results do not indicate a placebo effect of external bracing for patients with ankle instability and a history of unilateral ankle sprain. Furthermore, sagittal plane knee kinematics appear to remain unaffected by bracing during single-legged landing, owing to the limited effects of bracing on sagittal ankle kinematics. These results highlight the role of brace design on biomechanical function during sports-related and injury-prone movements. Clinical Relevance: Athletes prone to reinjury after lateral ankle sprain may benefit from brace designs that allow for full sagittal range of motion but restrict only frontal plane motion.