bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of a single preoperative dose of antibiotics on the early implant failure rate. A randomized clinical trial
Authors: Kashani Hossein , Hilon Jack , Rasoul Mahdi Hasan , Friberg Bertil 
Published: March 2019

AbstractBackgroundThe use of a preoperative single dose of antibiotics as routine in conjunction with implant surgery is controversial, in light of the unclear effect on early implant failure rate and risk for development of resistant bacterial strains.PurposeThis randomized clinical trial compared the early implant failure rates in two different patient cohorts: One group receiving a single dose of preoperative antibiotics (AB group) and one group receiving no antibiotics, prior to implant surgery (noAB group).Materials and MethodsPatients were referred for treatment at four specialist clinics in the county council of West Sweden, Vastra Gotaland and randomly assigned into one of the two groups. A total of 447 patients received 963 implants were included in the study.Of these, 223 patients (535 implants) belonged to the AB‐group and 224 patients (428 implants) to the noAB‐group. Four commercial implant brands were utilized, albeit one system was only represented with four implants.The outcome was evaluated after 4 months using either a one‐stage or two‐stage procedure. The surgical procedures were performed by experienced implant surgeons and the surgical protocol for implant placement follows standard. Failure was defined as removal of an implant for any reason. The study outcomes were statistically analyzed to evaluate the differences between the two groups.ResultsTwelve implants failed in 11 patients for the AB group, and 32 implants failed in 29 patients for the noAB group. Preoperative antibiotics, AB group, had significantly (P < 0.0011) lower implant failure 2.2% compared to 7.5% in the noAB group analyzed on implant level adjusted for dependence within patients, OR = 0.30, 95% confidence interval (0.14‐0.62).ConclusionAdministration of a single dose of antibiotics in conjunction with implant placement surgery resulted in a statistically significant lower early implant failure rate compared to when no antibiotics were used.
Effects of air abrasive decontamination on titanium surfaces: A systematic review of in vitro studies
Authors: Moharrami Mohammad , Perrotti Vittoria , Iaculli Flavia , Love Robert M. , Quaranta Alessandro 
Published: March 2019

AbstractBackgroundAir abrasion (AA) is one of the decontamination methods that have demonstrated promising results in treating peri‐implant diseases.PurposeThis systematic review aimed at evaluating the in vitro effect of AA on surface change, cleaning efficacy, and biocompatibility of titanium surfaces and at comparing it with other decontamination methods.Materials and MethodsA comprehensive search was conducted up to April 2018 using PubMed, Scopus, and Google Scholar databases to identify studies on the decontamination effect of AA. All types of titanium surfaces, abrasive powders, contaminated surfaces, and measuring methods were included.ResultsOverall, 1502 articles were identified. After screening the titles and abstracts, and carefully reading the full‐texts, 48 articles published between 1989 and 2018 were selected. AA was considered almost safe, particularly for the nonmodified surfaces. Nevertheless, harder powders such as sodium bicarbonate tended to damage the surface more than glycine. AA resulted in surface change similar to plastic curettes and Er: YAG lasers. Regarding the cleaning efficacy, there was no significant difference between glycine and sodium bicarbonate, but different mixtures of calcium phosphate, hydroxyapatite, and erythritol were superior to glycine. AA was superior or equal to all other decontamination methods in cleaning. Regarding biocompatibility, AA was more successful in preserving biocompatibility for noncontaminated surfaces compared with contaminated surfaces and when used with erythritol and osteoinductive powders.ConclusionsAA can efficiently remove contamination without serious damage to the surface. The main drawback of the AA method seems to be its limitation in restoring the biocompatibility of the surface.
Twenty‐first Century Industrial Policy in a Small Developing Country: The Challenges of Reviving Manufacturing in Rwanda
Authors: Behuria Pritish 
Published: March 2019

ABSTRACTThe Rwandan government — widely lauded for its political commitment to development — has refocused its efforts on reviving growth in the manufacturing sector. This article examines how pressures from different levels — international, regional and domestic — have shaped the evolving political economy of two priority sectors (apparel and cement). To achieve its goals of manufacturing sector growth, the Rwandan government aims to access foreign markets (on preferential terms) and larger regional markets while developing effective state–business relationships with locally based firms. Despite the government's political commitment to reviving its manufacturing sector, its strategy has been both shaped and impeded by shifting pressures at the international level (through Rwanda's recent suspension from the African Growth and Opportunity Act), the regional level (through competition from regional firms) and the domestic level (through over‐reliance on single firms). Within the current industrial policy literature, there is limited reflection on how developing countries are dealing with the multi‐scalar challenges of enacting industrial policy in a much‐changed global trading environment. This article contributes to the industrial policy literature by addressing this lacuna.
Beyond Color‐Blind and Color‐Conscious: Approaches to Racial Socialization Among Parents of Transracially Adopted Children
Authors: Killian Caitlin , Khanna Nikki 
Published: March 2019

ObjectiveTo examine how parents of transracially adopted children think about and practice ethnic–racial socialization.BackgroundPrevious research has highlighted how some parents are color‐blind and others are color‐conscious, yet these 2 categorizations fail to cover the range and fluidity of adoptive parents' approaches to ethnic socialization.MethodSemistructured interviews were conducted with 34 parents of children with Asian, Latino, and Black ancestry. Parents were recruited through adoption agencies and support groups, personal contacts, and snowball sampling and were asked about attempts and concerns in ethnically and racially socializing their children. Interviews were recorded, transcribed, and coded for common themes using the grounded theory method.ResultsSome parents downplayed race/ethnicity, but our findings elucidate their range of motivations from “protecting” their children from a racialized society to prioritizing other goals. More parents attempted to ethnically socialize but did so in varied ways, such as buying consumer items or forging relationships with people of their children's ethnic group. Compared with “color‐conscious” parents of Asian and Latino children, “color‐conscious” parents of Black children were more likely to emphasize preparation for bias.ConclusionAdoptive parents can vacillate between minimizing the impact of race to talking about steps taken to ethnically socialize children. Some parents note a profound change in their perspective at some point after adopting their children.ImplicationsDelving into more than 2 approaches to ethnic socialization and identifying changes over time affords a deeper understanding of parents' perspectives and behaviors and helps researchers interpret the mixed results found in past studies.
The impact of business group affiliation on stock price informativeness: Evidence from an emerging market
Authors: Küllü A. Melih , Dyer Doug , Yilmaz Gokhan , Sharma Zenu 
Published: March 2019

AbstractThis paper examines the relationship between business group affiliation and stock price informativeness in an emerging market setting. We use stock price synchronicity as a measure, and study the impact of group affiliation‐specifically the extent of affiliation, ownership structure and existence of group bank‐on firm specific information content. Results reveal that the amount of firm‐specific information capitalized into stock prices tends to be lower(higher)when the firm is group‐affiliated(unaffiliated), indirectly(directly)owned, and affiliated group has(does not have)a group bank. Additionally, the extent of group affiliation maintains a non‐linear relationship with synchronicity, suggesting that the perception of higher versus lower levels of group ownership differs.
What is the impact of problem loans on Japanese bank productivity growth?
Authors: Mamatzakis Emmanuel , Matousek Roman , Vu Anh Nguyet 
Published: March 2019

AbstractThis paper examines for the first time the impact of problem loans on Japanese productivity growth. We exploit a new data set of Japanese problem loans classified into two categories: bankrupt and restructured loans. We opt for a novel and flexible productivity growth decomposition that allows to measure the direct impact of these problem loans on productivity growth. The results reveal that Japanese bank productivity growth was severely constrained by bankrupt and restructured loans early in 2000s, whilst some persistence of the negative impact of problem loans on productivity growth is observed in the late 2000s. Thereafter, there is only some partial recovery in the productivity growth from 2012 to 2015. Further, we also perform cluster analysis to examine convergence or divergence across regions and over time. We observe limited convergence, though Regional Banks seem to form clusters in some regions.
SCFFbxw7 ubiquitylates KLF7 for degradation in a manner dependent on GSK‐3‐mediated phosphorylation
Authors: Sugiyama Shigeaki , Yumimoto Kanae , Inoue Ippei , Nakayama Keiichi I. 
Published: March 2019

AbstractThe biological relation between ubiquitin ligases and their substrates has been largely unclear. We previously developed a method—differential proteomics‐based identification of ubiquitylation substrates (DiPIUS)—for the comprehensive identification of substrates for a given ubiquitin ligase. We have now applied DiPIUS to the F‐box protein Fbxw7 in three cell lines (mHepa, Neuro2A and C2C12) and thereby identified Krüppel‐like factor 7 (KLF7) as a candidate substrate of the SCFFbxw7 ubiquitin ligase complex. KLF7 was shown to interact with Fbxw7 and to undergo Fbxw7‐mediated polyubiquitylation. The stability of KLF7 was increased by depletion of Fbxw7, mutation of a putative Cdc4 phosphodegron (CPD) of KLF7 or exposure to inhibitors of glycogen synthase kinase‐3 (GSK‐3). Over‐expression of Fbxw7 in Neuro2A cells down‐regulated expression of the p21Cip1 gene, which is a transcriptional target of KLF7 in neuronal differentiation and maintenance. Despite the presence of an almost identical CPD sequence in KLF6, the closest paralog of KLF7, mutation of this sequence affected neither the interaction of KLF6 with Fbxw7 nor its half‐life. Our results suggest that KLF7, but not KLF6, is a bona fide substrate of SCFFbxw7, and that control of KLF7 abundance by SCFFbxw7 might contribute to the regulation of neuronal differentiation and maintenance.
Magnetic Resonance Imaging of Nonaqueous Phase Liquid Distribution in Unconsolidated Soils Using Discriminatory Freezing
Authors: Kiaalhosseini Saeed , Kohn Benjamin , Watson A. Ted , Sale Tom C. , Blotevogel Jens 
Published: March 2019

AbstractOrganic contaminants present as nonaqueous phase liquids (NAPLs) in the subsurface often pose a long‐term risk to human health and the environment. Investigating the distribution of NAPLs in porous media remains a major challenge in risk assessment and management of contaminated sites. Conventional soil coring and monitoring wells have been widely used over past decades as the primary means of subsurface investigation to determine NAPL extent. Known limitations of conventional approaches have led us to explore an alternative or a complementary technique to provide high‐quality information of NAPL source zone architecture. This work advances an imaging tool for a variety of organic NAPL contaminants in unconsolidated soils through magnetic resonance imaging (MRI) of frozen cores. Using trichloroethylene (TCE) ando‐xylene as model species, we illustrate that discriminatory freezing of water, while keeping the NAPL in a liquid state, enables high‐resolution qualitative delineation of NAPL distribution within porous media. This novel approach may help improve site conceptual models and consequentially lead to highly tailored, more efficient remedial measures.
Core–shell NTC materials with low thermal constant and high resistivity for wide‐temperature thermistor ceramics
Authors: Liu Ting , Zhang Huimin , Ma Panfei , Chang Aimin , Jiang Hui 
Published: March 2019

AbstractCore–shell structures have been proposed to improve the electrical properties of negative‐temperature coefficient (NTC) thermistor ceramics. In this work, Al2O3‐modified Co1.5Mn1.2Ni0.3O4 NTC thermistor ceramics with adjustable electrical properties were prepared through citrate‐chelation followed by conventional sintering. Co1.5Mn1.2Ni0.3O4 powder was coated with a thin Al2O3 shell layer to form a core–shell structure. Resistivity (ρ) increased rapidly with increasing thickness of the Al2O3 layer, and the thermal constant (B) varied moderately between 3706 and 3846 K. In particular, Co1.5Mn1.2Ni0.3O4@Al2O3 ceramic with 0.08 wt% Al2O3 showed the increase of ρ double, and the change in its B was less than 140 K. The Co1.5Mn1.2Ni0.3O4@Al2O3 NTC ceramics showed high stability, and their grain size was relatively uniform due to the protection offered by the shell. The aging coefficient of the ceramic was less than 0.2% after aging for 500 hours at 125°C. Taken together, the results indicate that as‐prepared Co1.5Mn1.2Ni0.3O4@Al2O3 NTC ceramics with a core–shell structure may be promising candidates for application as wide‐temperature NTC thermistor ceramics.
A nondestructive intelligent approach to real‐time evaluation of chicken meat freshness based on computer vision technique
Authors: Taheri‐Garavand Amin , Fatahi Soodabeh , Shahbazi Feizollah , de la Guardia Miguel 
Published: March 2019

AbstractIn this study, the capability of a procedure based on combination of computer vision (CV) and artificial intelligence techniques examined for intelligent and nondestructive prediction of chicken meat freshness during the spoilage process at 4°C. The proposed system comprises the following stages: capture images, image preprocessing, image processing, computing channels, feature extraction, feature selection by a hybrid of genetic algorithm (GA) and artificial neuronal network (ANN), and prediction by using ANN. The number of neurons in input layer was determined 33 (selected features) and freshness used as the output. The ideal ANN model was obtained with 33‐10‐1 topology. The high performance of the model was provided with a correlation coefficient of 0.98734 and MSE of 0.002045. The encouraging results of the current study obviously indicated the high potential of CV‐based system combined with an intelligence method as a smart, nondestructive, and reliable technique for online evaluation of chicken meat freshness.Practical applicationDiagnosis and estimation of chicken meat freshness are considered a significant concern in meat quality for consumers. Computer Vision as a novel nondestructive technique can be utilized to evaluate the quality of products. We present the potential of computer vision‐based method as a smart, nondestructive, and reliable method for online prediction of the freshness of chicken meat.
Treatment Modalities and Survival in Older Adults with Metastatic Colorectal Cancer in Real Life
Authors: Gouverneur Amandine , Bezin Julien , Jové Jérémy , Bosco‐Lévy Pauline , Fourrier‐Réglat Annie , Noize Pernelle 
Published: March 2019

OBJECTIVESMetastatic colorectal cancer (mCRC) is increasingly treated with targeted therapies, but little is known about real‐life mCRC treatment in older adults. The aims were to describe the real‐life first‐line treatment modalities in older adult mCRC patients, to identify factors associated with treatment modalities, and to evaluate survival with regard to treatment modalities.PATIENTS AND METHODSA cohort of mCRC patients aged 65 years and older at diagnosis was identified between 2009 and 2013 using French national healthcare insurance system claims data. Treatment modalities were: treatment with one or more anticancer medication vs best supportive care and, among treated patients, treatment with targeted therapy vs conventional chemotherapy alone. Multivariate logistic regression was used to identify factors associated with treatment by anticancer medication and by targeted therapy. Cox proportional hazards models were used to assess the independent effect of treatment modalities on overall survival while adjusting for baseline covariates identified with logistic regression.RESULTSA total of 503 patients were included with a median age of 78 years (54% were men). Of these, 299 (59%) were treated with anticancer medications. Among treated patients, 131 (44%) received targeted therapy. In multivariate analysis, age 75 years or older, renal failure, malnutrition, and five or more concomitant medications were associated with a lower likelihood of treatment with anticancer medications. Among treated patients, age 75 years or older, history of cancer, lymph node metastases, and a single metastatic site were associated with a lower likelihood of treatment with targeted therapy. Multivariate Cox proportional hazards models found that treatment with any anticancer medication tended to be associated with a lower risk of death; treatment with targeted therapy was not significantly associated.CONCLUSIONA more appropriate prescription of anticancer medications in the older adult will require the definition of more explicit criteria to avoid undertreatment. The real benefit of targeted therapies vs conventional chemotherapy alone needs to be confirmed in this population. J Am Geriatr Soc 67:913–919, 2019.
Comparison of three different apex locators in determining the working length of mandibular first molar teeth with irreversible pulpitis compared with an intraoral periapical radiograph: A block randomized, controlled, clinical trial
Authors: Vanitha Sadashivam , Sherwood I. Anand 
Published: March 2019

AbstractAimThe aim of the present study was to assess the clinical accuracy APEX and 0.5 marks of three different apex locators – iPex II, Root ZX, and Apex ID – before and after canal preparation in the mandibular first molar.MethodsSixty patients between the ages of 13‐60 years participated in the study. After access gaining and canal preparation stages files were inserted with the apex locator clip attached until the electronic apex locators (EALs) shows readings of APEX and 0.5 marks and same is confirmed with periapical radiographs. Eighteen apex locator readings were recorded from each tooth, and 1080 readings were obtained from the 60 patients.ResultsDifferences among readings from apex locators and radiographic readings were assessed using paired t test. Only in two patients (1 male and 1 female) were the APEX mark readings different from the radiograph estimation. When the 0.5 mark readings of three different EALs were compared with each other, we could observe that the readings from Root ZX differed significantly (P < 0.05).ConclusionsIn the present study, we observed the negligible differences in readings between the EAL at the APEX mark readings, coinciding with the radiographic observation. Clinically, we recommend the apical foramen be located with the apex locators’ APEX mark readings prior to identifying the apical constriction position.
AGAMOUS AND TERMINAL FLOWER controls floral organ identity and inflorescence development in Medicago truncatula
Authors: Zhu Butuo , Li Hui , Hou Yifeng , Zhang Pengcheng , Xia Xiuzhi , Wang Na , Wang Hui , Mysore Kirankumar S. , Wen Jiangqi , Pei Yanxi , Niu Lifang , Lin Hao 
Published: March 2019

SummaryAngiosperms integrate a multitude of endogenous and environmental signals to control floral development, thereby ensuring reproductive success. Here, we report the identification of AGAMOUS AND TERMINAL FLOWER (AGTFL), a novel regulator of floral development in Medicago truncatula. Mutation of AGTFL led to the transformation of carpels and stamens into numerous sepals and petals and altered primary inflorescence identity. AGTFL encodes a nucleus‐localized protein containing a putative Myb/SANT‐like DNA‐binding domain and a PKc kinase domain. Molecular and genetic analyses revealed that AGTFL regulates the transcription of MtAGs and MtTFL1 to control floral organ identity and inflorescence development.
External vascular compression by hyaluronic acid filler documented with high‐frequency ultrasound
Authors: Lima Vanessa Guimaraes de Freitas , Regattieri Neysa Aparecida Tinoco , Pompeu Marcelo Faro , Costa Izelda Maria Carvalho 
Published: March 2019

SummaryWe present a case report of a hyaluronic acid filler‐induced complication documented using high‐frequency ultrasound. We regard the scientific value of the case as indicating the benefit that ultrasound provides for the management and documentation of this complication. This technology has been becoming increasingly widespread in the care of patients who experience unwanted effects of hyaluronic acid filler because it can be used for the high‐resolution visualization of skin layers as well as the differentiation of filler types and their relationships with adjacent tissues (via gray scale or B‐mode ultrasound) and blood vessels (via color Doppler ultrasound). In addition, it was possible to conclude that external vascular compression causes clinical repercussions, a fact that is often questioned by some dermatologists. This questioning is based on the vast vascularization and anastomosis of arteries of the face, which should permit compensation for vascular compression. However, in this case, there was no doubt that compression caused a region of low output with the clinical manifestation of peri‐oral pallor. Ultrasound was used to document the compression of a vessel by the filler; after application of hyaluronidase, increased vessel lumen and clinical reversal of hypoperfusion in the affected area were observed.
Intergenerational Transmission of Female Genital Cutting: Community and Marriage Dynamics
Authors: Boyle Elizabeth Heger , Svec Joseph 
Published: March 2019

AbstractObjectiveThis study examined how characteristics of households and communities are implicated in the intergenerational transmission of gender inequality and particularly female genital cutting (FGC).BackgroundHuman capital perspectives suggest that socioeconomic inequality predicts FGC continuation. This study contributes to discussions of institutional change by examining the association of decisions to forego FGC with household decision making patterns and community gender norms.MethodMultilevel logistic regression was deployed to analyze a pooled sample (N = 12,144) of six demographic and health surveys from Burkina Faso, Egypt, Guinea, Kenya, Mali, and Nigeria. A series of models examined how decision making styles, both at the household and community levels (2,524 demographic and health survey cluster aggregations), and community levels of FGC correspond with the risk of having a daughter cut.ResultsThe results show that daughters are less likely to be cut when parents make key household decisions jointly. Autonomous decision making by women at the community level was associated with lower odds of daughters being cut. However, at the community level, the impacts of women's household decision making were attenuated when FGC was more prevalent.ConclusionThe findings suggest that women's decision making status is an important factor in FGC abandonment, although that association is less robust when FGC is highly institutionalized. This study provides new insights into how women, families, and communities can disrupt the intergenerational transmission of behaviors associated with institutionalized gender inequality.