bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mesoscopic approach for simulating nanofluid flow and heat transfer in a finned multi-pipe heat exchanger
Authors: Liu Jia-Bao , Bayati Morteza , Abbas Mazhar , Rahimi Alireza , Naderi Mohammad 
Published: July 2019

PurposeThe lattice Boltzmann method is used to simulate the nanofluid flow and heat transfer inside a finned multi-pipe heat exchanger.Design/methodology/approachThe heat exchanger is filled with CuO-water nanofluid. The Koo–Kleinstreuer–Li (KKL) model is used to estimate the dynamic viscosity and considering the Brownian motion in the simulation. On the other hand, the influence of nanoparticles’ shapes on the heat transfer rate is considered, and the best efficient shape is selected to be used in the investigation.FindingsThe Rayleigh number, nanoparticle concentration and the thermal arrangements of internal active fins and bodies are the governing parameters. In addition, the impacts of these two parameters on the nanofluid flow, heat transfer rate, local and total entropy generation and heatline visualization are analyzed, comprehensively.Originality/valueThe originality of this work is using of lattice Boltzmann method for simulation of nanofluid flow and heat transfer during natural convection in a heat exchanger. Furthermore, influence of the shape of nanoparticles on the thermo-physical properties of nanofluid is analyzed using Koo–Kleinstreuer–Li correlation.
Understanding the webrooming phenomenon
Authors: Aw Eugene Cheng-Xi 
Published: July 2019

PurposeThe purpose of this paper is to propose and empirically test a model encompassing antecedents of webrooming, an emerging shopping behaviour in omnichannel retailing. This study delineates the impacts of shopping motivation, perceived channel-related benefits and costs on webrooming intention.Design/methodology/approachA questionnaire-based survey was conducted using a purposive sampling technique. A total of 300 responses were collected, and data were analysed using Partial Least Square Structural Equation Modelling.FindingsShopping motivation, such as efficiency shopping and bargain hunting, negatively influenced webrooming intention. Immediate possession positively influenced webrooming intention. With regard to perceived costs of webrooming, purchase effort and expected price loss negatively influenced webrooming intention. An additional exploratory analysis uncovered the moderating role of efficiency shopping.Originality/valueThis study provides empirical evidence for the antecedents of webrooming intention and expands the understanding of this emerging yet largely unexplored cross-channel behaviour.
An empirical assessment of employer branding as a form of sport event sponsorship
Authors: Karjaluoto Heikki , Paakkonen Lasse 
Published: July 2019

PurposeThe purpose of this paper is to expand and test Backhaus and Tikoo’s (2004) employer branding (EB) conceptual framework from the perspective of internal EB in a sport event sponsorship context.Design/methodology/approachThis study developed a set of hypotheses, which were tested in the context of a business-to-business multinational organization’s sport event sponsorship project. Empirical data were collected from 716 employees of the case company after the sponsorship project was complete.FindingsThe results support all the hypotheses and reveal that a sport event sponsorship project can act as a means to achieving EB goals in the investigated context.Research limitations/implicationsThe sample of the study was limited to the existing personnel of one case company. The study measures the effects at a single point in time, thus the findings should be validated with longitudinal research design.Practical implicationsThe results propose that companies can benefit from integrating sport sponsorship with internal EB. Practitioners are advised to create sponsorship projects that involve current employees effectively.Originality/valueThe study adds to the literature by being among the first empirical studies to have tested the effects of EB among current employees via a sponsorship project.
Study on laser sintering of pine/co-PES composites and the investment casting process
Authors: Zhang Hui , Bourell David , Guo Yanling , Zhang Xiaodong , Zhuang Yu , Yu Yueqiang , Jiang Kaiyi , Helal Wasim M.K. 
Published: July 2019

Purpose
A pine/co-PES composite (PCPES composite) was proposed as the feedstock for powder bed fusion (laser sintering, LS). This paper aims to provide some necessary experimental data and the theoretical foundation for LS of pine/co-PES, especially for the application of using the laser-sintered pine/co-PES parts as complex structural patterns in investment casting.

Design/methodology/approach
The PCPES composites with different pine loadings were mixed mechanically. The composite’s preheating temperature and processing temperature during LS were determined experimentally based on the material’s thermal behavior. The effects of pine powder on the binding mechanism of PCPES composites were discussed through analyzing the microstructure of the laser-sintered parts’. Mechanical properties and dimensional precision of laser-sintered PCPES parts in different pine loadings were tested, and the parts’ mechanical properties were strengthened by wax-infiltration post-processing. The influence extents of process parameters on the mechanical properties of laser-sintered 20 Wt.% pine/co-PES parts were investigated using a 1/2 fractional factorials experiment.

Findings
20 Wt.% pine/co-PES is considered to be a promising wood-plastic composite for laser sintering. The relationship between mechanical strength of its laser-sintered parts and process parameters was built up using mathematical formulas. Experimental results show density, tensile strength, flexural strength and surface roughness of laser-sintered 20 Wt.% pine/co-PES parts are improved by 72.7-75.0%, 21.9-111.3%, 26.8-86.2%, 27.0-29.1% after post-process infiltration with a wax. A promising application of the wax-infiltrated laser-sintered parts is for investment casting cores and patterns.

Research limitations/implications
The proper process parameters and forming properties of laser-sintered parts are limited to the results of laser sintering experiments carried on using AFS 360 rapid prototyping device.

Originality/value
This investigation not only provides a new feedstock for laser sintering with the advantages of low cost and fabricability but also uses an advanced technique to produce personalized wood-plastic parts efficiently. Mathematical models between mechanical properties of laser-sintered PCPES parts and LS process parameters will guide the further LS experiments using the 20 Wt.% pine/co-PES composite. Besides, the laser-sintered PCPES parts after wax-infiltration post-processing are promising as complex structural patterns for use in investment casting.
Breaking a cycle of perceived failure: The process of making changes toward a more balanced lifestyle
Authors: Lund Kristine , Argentzell Elisabeth , Bejerholm Ulrika , Eklund Mona 
Published: July 2019

IntroductionBalancing Everyday Life (BEL) is a new lifestyle intervention for mental health services users, developed to support meaningful engagement in daily activities and a balanced lifestyle. This study aimed at exploring the BEL participants’ process of making lifestyle changes.MethodsThis constructivist grounded theory study took place in Sweden from 2013–2017 and explored the processes of 19 BEL participants when making lifestyle changes. Data were collected through 29 interviews.ResultsA process of breaking a cycle of perceived failure and making changes toward a more balanced lifestyle was constructed, consisting of five categories: Going at it gently: change is an on‐going process; Support for progress, permission to fail; Prioritising and setting boundaries; Adjusting for a sustainable balance; and Caring for a valued self. Each category included a strategy for change as well as a related inner change. Strategies involved learning and trying techniques for making changes toward a more balanced lifestyle, whereas the personal changes often involved a more self‐compassionate approach and allowing oneself to utilise these techniques.ConclusionThe results contribute to knowledge in the process of making lifestyle changes, specifically, how strategies for change and inner changes interact and can support personal recovery toward mental health. This knowledge could help to support clients in making personally meaningful changes toward a more balanced lifestyle as well as inform future research in the process of making change.
Sub‐optimal treatment of paediatric migraine in an emergency department: An observational study
Authors: Klim Sharon , Krieser David , Kelly Anne‐Maree 
Published: July 2019

AbstractObjectivesTo describe treatment of children presenting to an Australian ED with a final ED diagnosis of migraine.MethodsPlanned substudy of a retrospective cohort study of the epidemiology of headache in children was done. Primary outcome of interest was treatment administered in the ED.ResultsThirty‐five children were studied. The most commonly used medications were non‐steroidal anti‐inflammatory drugs, paracetamol and ondansetron. Specific antimigraine therapy was used uncommonly. Fourteen percent of children received an opiate.ConclusionTreatment of migraine in children was not consistent with the available evidence regarding agents' relative effectiveness. The use of opiates is concerningly high.
Performance of the revised 2016 fibromyalgia diagnostic criteria in Korean patients with fibromyalgia
Authors: Kang Ji‐Hyoun , An Minjeong , Choi Sung‐Eun , Xu Haimuzi , Park Dong‐Jin , Lee Jung‐Kil , Lee Shin‐Seok 
Published: July 2019

AbstractAimRecently, the revised 2016 version of the 2010/2011 fibromyalgia (FM) criteria was released. No study has yet assessed whether the 2016 criteria perform better than the previous criteria. Therefore, we validated a Korean version of the revised FM criteria and explored whether they were better than the previous criteria in terms of diagnostic accuracy.MethodsWe enrolled 86 FM patients and 89 patients with various rheumatological disorders, including rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and myofascial pain syndrome. All patients were invited to complete a questionnaire that included the revised Fibromyalgia Impact Questionnaire (FIQ), the EuroQol five‐dimensional questionnaire (EQ‐5D), and the Multidimensional Health Assessment Questionnaire (MD‐HAQ).ResultsThe test‐retest reliability of the revised criteria was assessed in 30 patients after 2 weeks; the Spearman coefficient ranged from 0.616 to 0.910 and the Cronbach's alpha was 0.942 (95% CI: 0.930‐0.964). The revised criteria correlated significantly with the revised FIQ score (P < .001), the EQ‐5D score (P < .001), and the MD‐HAQ score (P < .001). Using the revised criteria, FM was diagnosed in 94.2% of patients with a prior diagnosis of FM, and in 10.1% of those with other rheumatological disorders. The sensitivity and specificity of the revised criteria were 93.1% and 90.7%, respectively. The area under the receiver operating characteristic curve of the revised criteria was 0.966, higher than those of the 1990, 2010, and 2011 criteria.ConclusionThe revised criteria are reliable and valid when used to diagnose patients with FM, and are better than the previous criteria.
Missense mutation in DNAJB13 gene correlated with male fertility in asthenozoospermia
Authors: Li W. N. , Zhu L. , Jia M. M. , Yin S. L. , Lu G. X. , Liu G. 
Published: July 2019

AbstractBackgroundThe most common type of male infertility is asthenospermia. We cloned DnaJ heat shock protein family member B13 (Dnajb13/DNAJB13), a type II HSP40 family member that is highly expressed in the testis. DNAJB13 plays a crucial role in sperm flagellar function.ObjectivesThe aim of this study was to investigate whether a correlation exists between DNAJB13 and low sperm motility in infertile men.Materials and methodsIn the present study, we performed a mutation screening of the DNAJB13 gene in 92 idiopathic asthenozoospermia patients and 200 men with normal fertility. Additionally, we used immunoelectron microscopy, co‐immunoprecipitation, mass spectrometric detection, indirect immunofluorescence assay, transmission electron microscopy studies, isobaric tags for relative and absolute quantitation, and multiple reaction monitoring studies to analyze changes in DNAJB13 protein.ResultsA novel c.106T>C mutation of DNAJB13 was present in nearly 10% (9/92) of idiopathic asthenozoospermia patients and was absent in 200 fertile men. A computer‐assisted sperm analyzer and transmission electron microscopy analysis using samples from 9 patients with DNAJB13 mutations demonstrated that most spermatozoa were immotile due to sperm tail defects. Multiple reaction monitoring results indicated that DNAJB13 protein levels were reduced after gene mutation. We achieved a pregnancy rate of 100% in 8 patients with DNAJB13 mutations using ICSI.Discussion and conclusionThe DNAJB13 heterozygous variant may affect fertility. ICSI can help these patients with low fertility to father children.
Oral immunization of mice with Lactococcus lactis expressing Shiga toxin truncate confers enhanced protection against Shiga toxins of Escherichia coli O157:H7 and Shigella dysenteriae
Authors: Sreerohini Sagi , Balakrishna Konduru , Parida Manmohan 
Published: July 2019

Regardless of the communal impact of Shiga toxins, till today neither a specific treatment nor licensed vaccine is available. Lactococcus lactis (L. lactis), generally regarded as safe organism, is well known to provide a valuable approach regarding the oral delivery of vaccines. This study was undertaken to evaluate the protective efficacy of Stx2a1 expressed in nisin‐inducible L. lactis, against Shiga toxins (Stx1, Stx2) in mouse model. Oral immunization of BALB/c mice with LL‐Stx2a1 elicited significant serum antibody titer with elevated fecal and serum IgA, along with minimized intestinal and kidney damage resulting in survival of immunized animals at 84% and 100% when challenged with 10 × LD50 of Escherichia coli O157 and Shigella dysenteriae toxins, respectively. HeLa cells incubated with immune sera and toxin mixture revealed high neutralizing capacity with 90% cell survivability against both the toxins. Mice immunized passively with both toxins and antibody mixture survived the observation period of 15 days, and the controls administered with sham sera and toxins were succumbed to death within 3 days. Our results revealed protective efficacy and toxin neutralization ability of LL‐Stx2a1, proposing it as an oral vaccine candidate against Shiga toxicity mediated by E. coli O157 and S. dysenteriae.
Review article: diagnosis and management of intestinal failure‐associated liver disease in adults
Authors: Bond Ashley , Huijbers Angelique , Pironi Loris , Schneider Stephane M. , Wanten Geert , Lal Simon 
Published: July 2019

SummaryBackgroundHepatic disturbances in the context of intestinal failure and parenteral nutrition (PN) are frequently encountered and carry a significant burden of morbidity and sometimes mortality. The term intestinal failure‐associated liver disease (IFALD) refers to liver injury due to intestinal failure and associated PN, in the absence of another evident cause of liver disease, encompassing a spectrum of conditions from deranged liver enzymes, steatosis/ steatohepatitis, cholestasis as well as progressive fibrosis, cirrhosis and end‐stage liver disease.AimsTo present an up to date perspective on the diagnosis/definition, aetiologies and subsequent management of IFALD and to explore future consideration for the condition, including pharmacological therapiesResultsIn adults using long‐term PN for benign chronic intestinal failure, 1%‐4% of all deaths are attributed to IFALD. The aetiology of IFALD is multifactorial and can be broadly divided into nutritional factors (eg lipid emulsion type) and patient‐related factors (eg remaining bowel anatomy). Given its multifaceted aetiology, the management of IFALD requires clinicians to investigate a number of factors simultaneously. Patients with progressive liver disease should be considered for combined liver‐intestine transplantation, although multivisceral grafts have a worse prognosis. However, there is no established non‐invasive method to identify progressive IFALD such that liver biopsy, where appropriate, remains the gold standard.ConclusionA widely accepted definition of IFALD would aid in diagnosis, monitoring and subsequent management. Management can be complex with a number of factors to consider. In the future, dedicated pharmacological interventions may become more prominent in the management of IFALD.
A general framework for modeling population abundance data
Authors: Besbeas Panagiotis , Morgan Byron J. T. 
Published: July 2019

AbstractTime‐series data resulting from surveying wild animals are often described using state‐space population dynamics models, in particular with Gompertz, Beverton‐Holt, or Moran‐Ricker latent processes. We show how hidden Markov model methodology provides a flexible framework for fitting a wide range of models to such data. This general approach makes it possible to model abundance on the natural or log scale, include multiple observations at each sampling occasion and compare alternative models using information criteria. It also easily accommodates unequal sampling time intervals, should that possibility occur, and allows testing for density dependence using the bootstrap. The paper is illustrated by replicated time series of red kangaroo abundances, and a univariate time series of ibex counts which are an order of magnitude larger. In the analyses carried out, we fit different latent process and observation models using the hidden Markov framework. Results are robust with regard to the necessary discretization of the state variable. We find no effective difference between the three latent models of the paper in terms of maximized likelihood value for the two applications presented, and also others analyzed. Simulations suggest that ecological time series are not sufficiently informative to distinguish between alternative latent processes for modeling population survey data when data do not indicate strong density dependence.
Recalculating route: dispersal constraints will drive the redistribution of Amazon primates in the Anthropocene
Authors: Sales Lilian Patrícia , Ribeiro Bruno R. , Pires Mathias M. , Chapman Colin A. , Loyola Rafael 
Published: July 2019

Climate change will redistribute the global biodiversity in the Anthropocene. As climates change, species might move from one place to another, due to local extinctions and colonization of new environments. However, the existence of permeable migratory routes precedes faunal migrations in fragmented landscapes. Here, we investigate how dispersal will affect the outcome of climate change on the distribution of Amazon's primate species.We modeled the distribution of 80 Amazon primate species, using ecological niche models, and projected their potential distribution on scenarios of climate change. Then, we imposed landscape restrictions to primate dispersal, derived from a natural biogeographical barrier to primates (the main tributaries of the Amazon river) and an anthropogenic constraint to the migration of many canopy‐dependent animals (deforested areas). We also highlighted potential conflict zones, i.e. regions of high migration potential but predicted to be deforested.Species response to climate change varied across dispersal limitation scenarios. If species could occupy all newly suitable climate, almost 70% of species could expand ranges. Including dispersal barriers (natural and anthropogenic), however, led to range expansion in only less than 20% of the studied species. When species were not allowed to migrate, all of them lost an average of 90% of the suitable area, suggesting that climate may become unsuitable within their present distributions.All Amazon primate species may need to move as climate changes to avoid deleterious effects of exposure to non‐analog climates. The effect of climate change on the distribution of Amazon primates will ultimately depend on whether landscape permeability will allow climate‐driven faunal migrations. The network of protected areas in the Amazon could work as ‘stepping stones’ but most are outside important migratory routes. Therefore, protecting important dispersal corridors is foremost to allow effective migrations of the Amazon fauna in face of climate change and deforestation.
Susceptibility of Coulter pine (Pinus coulteri) to western dwarf mistletoe (Arceuthobium campylopodum) in southern California
Authors: Mathiasen Robert L. 
Published: July 2019

AbstractThe susceptibility of Coulter pine (Pinus coulteri) to western dwarf mistletoe (Arceuthobium campylopodum) was evaluated in southern California. Eight stands infested with western dwarf mistletoe and dominated by Coulter and Jeffrey pines (Pinus jeffreyi) were sampled. Infection of Coulter pine was evaluated using circular plots established around large, severely infected Jeffrey pines and with rectangular transects. A total of 25 plots and 10 transects were sampled. In each plot and transect, live trees > 5 cm in diameter at breast height (1.4 m above the ground) were assigned a dwarf mistletoe rating (6‐class system). Nearly 600 Jeffrey pines and more than 400 Coulter pines were evaluated. Infection of Jeffrey and Coulter pines in the plots and transects averaged 96% and 97%, respectively. These data indicate that Coulter pine should be classified as a principal host of WDM and not as a secondary host as previously reported.
Role of virological serum markers in patients with both hepatitis B virus infection and diffuse large B‐cell lymphoma
Authors: Zhou Xiang , Wuchter Patrick , Egerer Gerlinde , Kriegsmann Mark , Mataityte Aiste , Koelsche Christian , Witzens‐Harig Mathias , Kriegsmann Katharina 
Published: July 2019

AbstractBackgroundCausality between hepatitis B virus (HBV) infection and diffuse large B‐cell lymphoma (DLBCL) was reported in various studies. However, the implication of different virological serum markers of HBV infection in patients with both HBV infection and DLBCL is not fully understood. The aim of this study was to investigate the impact of HBV markers on overall survival (OS) and progression‐free survival (PFS) in patients with both HBV infection and DLBCL.MethodsIn this study, patients (n = 40) diagnosed with both HBV infection and DLBCL were identified between 2000 and 2017. Six patients with hepatitis C virus (HCV) and/or human immunodeficiency virus (HIV) co‐infection were excluded from this study. We retrospectively analyzed patients’ demographic characteristics, treatment, and the prognostic impact of different HBV markers at first diagnosis of DLBCL (HBsAg, anti‐HBs, HBeAg, anti‐HBe, and HBV‐DNA) on OS and PFS.ResultsThe majority of patients (n = 21, 62%) had advanced disease stage (III/IV) at diagnosis. In the first‐line therapy, 24 patients (70%) were treated with R‐CHOP regimen (rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone). HBeAg positive patients had a trend toward inferior OS and PFS compared with HBeAg negative patients. Anti‐HBe positive patients had a statistically significant better OS and PFS compared with anti‐HBe negative group (both P < .0001). Viremia with HBV‐DNA ≥ 2 × 107 IU/L had a significant negative impact on OS and PFS (both P < .0001).ConclusionHigh activity of viral replication is associated with a poor survival outcome of patients with both HBV infection and DLBCL.