bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two-Stage Estimation and Variance Modeling for Latency-Constrained Variational Quantum Algorithms
Authors: Ha Yunsoo , Shashaani Sara , Menickelly Matt 
Published: November 2024

The quantum approximate optimization algorithm (QAOA) has enjoyed increasing attention in noisy, intermediate-scale quantum computing with its application to combinatorial optimization problems. QAOA has the potential to demonstrate a quantum advantage for NP-hard combinatorial optimization problems. As a hybrid quantum-classical algorithm, the classical component of QAOA resembles a simulation optimization problem in which the simulation outcomes are attainable only through a quantum computer. The simulation that derives from QAOA exhibits two unique features that can have a substantial impact on the optimization process: (i) the variance of the stochastic objective values typically decreases in proportion to the optimality gap, and (ii) querying samples from a quantum computer introduces an additional latency overhead. In this paper, we introduce a novel stochastic trust-region method derived from a derivative-free, adaptive sampling trust-region optimization method intended to efficiently solve the classical optimization problem in QAOA by explicitly taking into account the two mentioned characteristics. The key idea behind the proposed algorithm involves constructing two separate local models in each iteration: a model of the objective function and a model of the variance of the objective function. Exploiting the variance model allows us to restrict the number of communications with the quantum computer and also helps navigate the nonconvex objective landscapes typical in QAOA optimization problems. We numerically demonstrate the superiority of our proposed algorithm using the SimOpt library and Qiskit when we consider a metric of computational burden that explicitly accounts for communication costs. History: Accepted by Giacomo Nannicini, Area Editor for Quantum Computing and Operations Research. Accepted for Special Issue. Funding: This material is based upon work supported by the U.S. Department of Energy, Office of Science, National Quantum Information Science Research Centers and the Office of Advanced Scientific Computing Research, Accelerated Research for Quantum Computing program under contract number DE-AC02-06CH11357. Y. Ha and S. Shashaani also gratefully acknowledge the U.S. National Science Foundation Division of Civil, Mechanical and Manufacturing Innovation Grant CMMI-2226347 and the U.S. Office of Naval Research [Grant N000142412398]. Supplemental Material: The software that supports the findings of this study is available within the paper and its Supplemental Information ( https://pubsonline.informs.org/doi/suppl/10.1287/ijoc.2024.0575 ) as well as from the IJOC GitHub software repository ( https://github.com/INFORMSJoC/2024.0575 ). The complete IJOC Software and Data Repository is available at https://informsjoc.github.io/ .
Dresdner Opernarchiv digital. Ein neues Musikprojekt an der SLUB Dresden
Authors: Geck Karl Wilhelm 
Published: November 2024

Das DFG-geförderte Projekt beschäftigt sich mit der Digitalisierung von 1282 Notenmanuskripten (Partituren, Stimmensätzen sowie Chor- und Soufflierauszügen). Dazu kommen 268 korrespondierende Librettodrucke der SLUB. Bei dem genannten Material handelt es sich um ca. 650 Werke. Die zu bearbeitenden Werke kulminieren in 900.00 Scans zu einer öffentlich zugängigen und detailreich strukturierten Dokumentation.
"Archiv der Stimmen." Ein DFG-Projekt der Mediathek der SLUB Dresden
Authors: Rohrmüller Marc 
Published: November 2024

Gefördert von der DFG und ausgeführt durch die Mitarbeiter der Mediathek der Sächsischen Staatsbibliothek- Landes- und Universitätsbibliothek (SLUB), werden über einen Zeitraum von 2 Jahren 8500 Schellackplatten aus den Jahren 1896-1960 digitalisiert.Die entstandene Sammlung „Archiv der Stimmen“ beherbergt rund 17000 Vokalstücke. Darunter befinden sich neben Raritäten und Einzelstücken Berühmtheiten von Mozart über Puccini bis Schubert. Besonders akustische Aufnahmen aus der Sammlung des Malers Paul Wilhelm stehen im Zentrum der Arbeit.
Das DFG-Projekt "Kompetenzzentrum Forschung und Information Musik" (KoFIM) an der Staatsbibliothek zu Berlin - Preußischer Kulturbesitz
Authors: Eckhardt Wolfgang , Fromme Daniel , Neumann Julia , Schwinger Tobias 
Published: November 2024

Um optimale Bedingungen für das wissenschaftliche Arbeiten mit Handschriften aus dem 17. bis zum frühen 19. Jahrhundert zu ermöglichen, arbeitet die Staatsbibliothek zu Berlin eng mit dem RISM-Zentrum in Frankfurt a.M. an der Bildung eines Kompetenzzentrums Forschung und Information Musik.( KoFIM)Inhalt dieser Arbeit sind: a) die Erschließung von über 10000 Musikautographen, b) die digitale Dokumentation von Schreiberhänden, c) die digitale Dokumentation von Wasserzeichen und d) die Erfassung von Kopisten. Dabei ist man weniger bemüht, bekannte und schon gut erschlossene Werke der „großen Komponisten" zu verzeichnen als vielmehr hochinteressante Quellen, die bislang nur in Zettelform erschlossen sind.
Rezensionen
Authors: Moths Angelika , Leibnitz Thomas , Sühring Peter , Gordienko Marina , Günther Georg , Pütz Elisabeth 
Published: November 2024

„Avec discrétion“ – Rethinkig Froberger. Hrsg. von Andreas Vejvar und Markus Grassl. (A. Moths)Alberto Fassone: Anton Bruckner und seine Zeit. (Th. Leibnitz)Verena Mogl: „Juden, die ins Lied sich retten“. Der Komponist Mieszysław Weinberg (1919–1996) in der Sowjetunion. (P. Sühring)Musikausstellungen – Intention, Realisierung, Interpretation. Ein interdisziplinäres Symposium. Hrsg. von Andreas Meyer. (M. Gordienko)
Jean-Michel Nectoux: Gabriel Fauré. Catalogue des oeuvres. Werkverzeichnis. (G. Günther)Peter Ryom: Antonio Vivaldi. Thematisch-systematisches Verzeichnis seiner Werke (RV). 2., überarb. Aufl. von Federico Maria Sardelli. (G. Günther)Volker Timmermann: „...wie ein Mann mit dem Kochlöffel“. Geigerinnen um 1800. (E. Pütz)
Rezensionen
Authors: Feß Eike , Mücke Panja , Sühring Peter , Wolf Hans-Peter , Schneider Ullrich , Leibnitz Thomas 
Published: November 2024

Klangbeschreibung. Zur Interpretation der Musik Wolfgang Rihms. Hrsg. von Thomas Seedorf. (E. Feß)
Hans Joachim Marx / Steffen Voss: Die G. F. Händel zugeschriebenen Kompositionen 1700–1800 (HWV Anh. B). (P. Mücke)
Musikphilologie. Grundlagen – Methoden – Praxis. Hrsg. von Bernhard R. Appel und Reinmar Emans. (P. Sühring)
Engelbert Humperdinck. Ein biografisch-musikalisches Lesebuch. Hrsg. von Tim Michalak und Christian Ubber. (H.-P. Wolf)
Barbara Meier: Alban Berg. Biographie. (U. Scheideler)
Eva Neumayr und Lars E. Laubhold: Dommusikarchiv Salzburg (A–Sd). Thematischer Katalog der musikalischen Quellen, Reihe A. (Th. Leibnitz)
Eva Neumayr, Lars E. Laubhold und Ernst Hintermaier: Musik am Dom zu Salzburg. Repertoire und liturgisch gebundene Praxis zwischen hochbarocker Repräsentation und Mozart-Kult. (Th. Leibnitz)
Rezensionen
Authors: Sühring Dr. Peter , Wolf Barbara , Scheideler Dr. Ullrich , Gerberding Heiderose , Loy Dr. Felix 
Published: November 2024

Felix Mendelssohn Bartholdy. Analytische und rezeptionsgeschichtliche Perspektiven. Hrsg. von Birger Petersen und Jan Philipp Sprick. (P. Sühring)
Andreas N. Tarkmann, Johannes Kohlmann: Praktische Instrumentenkunde. (B. Wolf)
Eleonore Büning: Sprechen wir über Beethoven. Ein Musikverführer. (U. Scheideler)
Bernd Weikl: Singen. In der Oper, als Therapie und in der Post- und Postpostmoderne. (B. Wolf)
Berit Sandberg und Dagmar Frick-Islitzer: Die Künstlerbrille. Was und wie Führungskräfte von Künstlern lernen können. (H. Gerberding)
Silke Leopold: Leopold Mozart. „Ein Mann von vielen Witz und Klugheit“. Eine Biographie. (F. Loy)
Rapid stochastic spatial light modulator calibration and pixel crosstalk optimization
Authors: Schroff P. , Haller E. , Kuhr S. , La Rooij A. 
Published: November 2024

Holographic light potentials generated by phase-modulating liquid-crystal spatial light modulators (SLMs) are widely used in quantum technology applications. Accurate calibration of the wavefront and intensity profile of the laser beam at the SLM display is key to the high fidelity of holographic potentials. Here, we present a new calibration technique that is faster than previous methods while maintaining the same level of accuracy. By employing stochastic optimization and random speckle intensity patterns, we calibrate a digital twin that accurately models the experimental setup. This approach allows us to measure the wavefront at the SLM to within λ/170 in ~ 5 minutes using only 10 SLM phase patterns, a significant speedup over state-of-the-art techniques. Additionally, our digital twin models pixel crosstalk on the liquid-crystal SLM, enabling rapid calibration of model parameters and reducing the error in light potentials by a factor of ~ 5 without losing efficiency. Our fast calibration technique will simplify the implementation of high-fidelity light potentials in, for example, quantum-gas microscopes and neutral-atom tweezer arrays where high-NA objectives and thermal lensing can deform the wavefront significantly. Applications in the field of holographic displays that require high image fidelity will benefit from the novel pixel crosstalk calibration, especially for displays with a large field of view and increased SLM diffraction angles.
Burden and risk factors of suspected cholangiocarcinoma in high Opisthorchis viverrini endemic rural communities in southern Lao PDR
Authors: Homsana Anousin , Southisavath Phonesavanh , Kling Kerstin , Hattendorf Jan , Vorasane Savina , Paris Daniel Henry , Probst-Hensch Nicole , Sayasone Somphou , Odermatt Peter 
Published: November 2024

Introduction
Cholangiocarcinoma (CCA) is a major contributor to hepatobiliary mortality in the Lao People’s Democratic Republic (Lao PDR). Infection with the carcinogenic trematode Opisthorchis viverrini (OV), acquired through consumption of insufficiently-cooked river fish, is a known risk factor for the development of CCA. Together with OV, other risk factors contribute to the pathogenesis of CCA. We conducted this study to identify the burden of CCA and identify risk factors in high-risk communities in Lao PDR.

Method
A cross-sectional study was performed in Champasack and Savannakhet provinces, southern Lao PDR, where OV infection is highly endemic. We assessed hepatobiliary morbidity with abdominal ultrasound (US). In addition, multiple risk factors known or suspected to be associated with CCA were assessed such as OV infection (examined by Kato-Katz technique for stool examination), lifestyle risks (e.g. smoking and alcohol consumption by face-to-face questionnaire), co-morbidity (e.g. diabetes mellitus) and hepatitis B infection status, both serologically tested.

Results
In 3,400 participants, the overall prevalence of suspected CCA was 7.2% (95% confidence interval [95% CI] 5.4−9.6). The suspected CCA prevalence increased with age, and was higher in men at all ages. Almost all participants (88.3%) were infected with OV. In the multivariate regression analysis, suspected CCA was positively associated with OV infection (adjusted odds ratio [aOR] 3.4, 95% CI 1.7−6.5), and a history of cholecystectomy (aOR 2.7, 95% CI 1.5−4.9).

Conclusion
Our CCA screening in high OV prevalence rural areas of Lao PDR uncovers a high public health burden, primarily driven by elevated OV infection rates. Urgent interventions are needed to curb OV infection in these communities. Age and gender disparities in suspected CCA prevalence highlight the need for targeted efforts. Beyond OV, notable factors like a history of cholecystectomy offer valuable insights for preventive strategies. This research enhances our understanding of hepatobiliary morbidity and informs public health initiatives in Lao PDR.
Significant difference in gut microbiota Bifidobacterium species but not Lactobacillus species in colorectal cancer patients in comparison with healthy volunteers using quantitative real-time PCR
Authors: Esfandiari Fahime , Bakhshi Bita , Shahbazi Tayebe , Derakhshan-nezhad Elahe , Bahroudi Mahboube , Minaeeian Sara , Boustanshenas Mina , Alborzi Forough , Behboudi Behnam , Fazeli Mohamad Sadegh 
Published: November 2024

Background
Colorectal cancer (CRC), with a growing incidence trend, is one of the most diagnosed cancers and the second cause of cancer-related deaths worldwide. The literature has frequently focused attention on the correlation between the gut microbiota imbalance and CRC. The genera Lactobacillus and Bifidobacterium have recently received increasing attention because of their potential in restoring alterations in the gut microflora. Therefore, this study aimed to quantitatively evaluate the presence of lactobacilli and bifidobacterial strains in the fecal samples of CRC patients compared to healthy volunteers.

Methods
From 2018 to 2019, 25 confirmed CRC patients and 25 age- and gender-matched control subjects were enrolled in the study. Bacterial DNA was extracted from the fecal samples and the presence of lactobacilli and bifidobacterial strains were quantitatively determined using quantitative real-time PCR using genus-specific 16S rDNA primers.

Results
A significant decline in the abundance of bifidobacteria in CRC patients compared to healthy individuals (p value<0.003) was observed; however, no significant difference was observed between the two groups regarding the abundance of lactobacilli (p value<0.163). Correlation analysis showed a positive association between the lack of genetic history of CRC and the numbers of gut bifidobacteria and lactobacilli.

Conclusion
As a putative gut probiotic, depletion of bifidobacteria showed significant correlation to the development and progression of CRC; therefore, therapeutic use of these probiotic bacteria could be considered a possible adjuvant approach in disease management through modulation of the microbiota.
Comparison of physician-delivered models of virtual and home-based in-person care for adults in the last 90 days of life with cancer and terminal noncancer illness during the COVID-19 pandemic
Authors: Akhter Rabia , Stukel Thérèse A. , Chung Hannah , Bell Chaim M. , Detsky Allan S. , Downar James , Isenberg Sarina R. , Lapp John , Mokhtarnia Media , Stall Nathan , Tanuseputro Peter , Quinn Kieran L. 
Published: November 2024

Objective
To measure the association between types of serious illness and the use of different physician-delivered care models near the EOL during the COVID-19 pandemic.

Design, setting and participants
Population-based cohort study using health administrative datasets in Ontario, Canada, for adults aged ≥18 years in their last 90 days of life who died of cancer or terminal noncancer illness and received physician-delivered care models near the end-of-life between March 14, 2020 and January 24, 2022.

Exposure
The type of serious illness (cancer or terminal noncancer illness).

Main outcome
Physician-delivered care models for adults in the last 90 days of life (exclusively virtual, exclusively home-based in-person, or mixed).

Results
The study included 75,930 adults (median age 78 years, 49% female, cancer n = 58,894 [78%], noncancer illness n = 17,036 [22%]). A higher proportion of people with cancer (39.3%) received mixed model of care compared to those with noncancer illnesses (chronic organ failure 24.4%, dementia 37.9%, multimorbidity 28%). Compared to people with cancer, people with chronic organ failure (adjusted odds ratio [aOR], 1.61, 95% CI: 1.54 to 1.68) and those with multimorbidity ([aOR], 1.49, 95% CI: 1.39 to 1.59) had a higher odds of receiving virtual care than a mixed model of care. People with dementia had a higher odds of home-based in-person care than a mixed model of care ([aOR], 1.47, 95% CI 1.27, 1.71) and virtual care ([aOR], 1.40, 95% CI 1.20–1.62) compared to people with cancer.

Conclusion
A person’s type of serious illness was associated with different care models near the end-of-life. This study demonstrates persistent disease-specific differences in care delivery or possibly the tailoring of models of care in the last 90 days of life based on a person’s specific care needs.
Factors associated with self-reported suboptimal antiretroviral adherence and limited retention in care among people living with HIV who attend a large ART clinic in Panama City, Panama
Authors: Gabster Amanda , Díaz Fernández Félix , Pascale Juan Miguel , Orillac Angelique , Moreno-Wynter Samuel , Xavier Hall Casey D. , Flores Millender Eugenia , Wong Frank (´Frankie´) , Jhangimal Mónica , Yu-Pon Anyi , Rodríguez-Vargas Cristel , Arjona-Miranda Diógenes , Fuentes Bárbara , Henostroza Germán , Araúz Ana Belén 
Published: November 2024

Background
The prevalence of HIV in Panama is estimated to be 1.0%; only 71% of individuals on antiretroviral treatment (ART) were virally suppressed in 2022. This study aimed to describe the prevalence of suboptimal adherence (≥1 missed doses in previous four weeks) and limited retention in HIV care (≥1 missed HIV care appointments in previous 12 months) among adults (aged ≥18 years) who attended the most populous urban ART Clinic in Panama City.

Methods
In this cross-sectional study, participants completed a self-administered questionnaire. Univariable and bivariable analyses were used to describe the prevalence of suboptimal adherence and limited retention in HIV care. Multivariable logistic regression identified factors associated with suboptimal adherence at p<0.05.

Results
We included 375 participants (209 identified as men, 158 as women, 8 another gender). Of those who responded, 37.3% (n = 125/335) reported suboptimal adherence: 28.6% (n = 53/185) of men, 49.0% (n = 71/145) women, 20.0% (n = 1/5) another gender; p<0.01; 18.6% (n = 69/371) reported limited retention in care:13.6% (n = 28/206) men, 24.2% (n = 38/157) women, 37.5% (n = 3/8) another gender, p = 0.01. In multivariable analyses, suboptimal adherence was associated with gender (49.0%women vs. 28.6% men, AOR = 1.86, 95%CI:0.97–3.57), depressive symptoms:46.2% severe symptoms vs. 28.1% minimal-mild, AOR = 2.19,95%CI:0.96–5.04), and lifetime intimate partner emotional violence (IPV) 48.2% vs.no emotional IPV 32.2%, OR = 1.96,95%CI:1.15–2.90, and lifetime physical IPV 46.9% vs.no physical IPV 32.6%, OR = 1.82, 95%CI:1.15–2.90. In unadjusted analyses, limited retention in care was associated with gender (24.2%women vs.13.6% men OR = 2.03, 95%CI:1.18–3.49), difficulty paying rent/mortgage/utilities (22.6% vs.14.9% no difficulty paying, OR = 1.67,95%CI = 0.98–2.83); no variables were associated in the multivariable model.

Conclusions
This study found high prevalence of suboptimal ART adherence and limited retention in care, especially among women; these factors were associated with severe depressive symptoms, as well as lifetime emotional and physical IPV. These results show the need for integrated mental health and IPV intervention for all individuals, including focused support for women.
Incidence of long-term conditions in the Latin American community of London: A validation and retrospective cohort study of 890,922 primary care records, 2005–2022
Authors: Scuffell James , Bailey James , Dodhia Hiten , Durbaba Stevo , Ashworth Mark 
Published: November 2024

Background
Minoritised populations in the United Kingdom frequently identify in multiple ethnic groupings and therefore little is known of their health needs. There were 136,062 Latin American people recorded in the 2021 UK Census across six different ethnic groups.

Aim
Characterise the incidence of long-term conditions (LTCs) and multiple LTCs (mLTCs) amongst the Latin American community of London. Compare the incidence of LTCs in the Latin American population to other ethnic groups.

Design and setting
Retrospective cohort study using pseudonymised primary care data from 890,922 individuals in an urban, superdiverse area of London from 2005–2022.

Method
Latin American individuals were identified using country of birth, language and ethnicity codes, and validated against Census findings. Multivariable competing risks regression models estimated the effect of being Latin American, compared to the White British ethnic group, on incidence of 32 LTCs and risk factors relevant to urban populations.

Results
28,617 Latin American people were identified in this cohort, 3.2% of total. In multivariable analysis, compared to the White British ethnic group, being Latin American was associated with twice the rate of HIV/AIDS (hazard ratio (HR) 2.00; 95% confidence interval (CI) 1.65–2.43), 60% increased rate of diabetes (HR 1.61; 95%CI 1.47–1.77) and almost twice the rate of systemic lupus erythematosus and rheumatoid arthritis (HRs 2.28; 95% CI 1.18–4.38 and 1.69; 95% CI 1.32–2.17 respectively).

Conclusion
Using commonly-recorded primary care codes accurately and reliably identifies markedly higher risks of HIV/AIDS, diabetes and joint disease among London’s Latin American population. These data can be used to target inclusive and equitable health interventions.
Gut microbiota markers in early childhood are linked to farm living, pets in household and allergy
Authors: Ljung Annika , Gio-Batta Monica , Hesselmar Bill , Imberg Henrik , Rabe Hardis , Nowrouzian Forough L. , Johansen Susanne , Törnhage Carl-Johan , Lindhagen Gunhild , Ceder Margareta , Lundell Anna-Carin , Rudin Anna , Wold Agnes E. , Adlerberth Ingegerd 
Published: November 2024

Background
Children growing up on farms or with pets have a lower risk of developing allergy, which may be linked to their gut microbiota development during infancy.

Methods
Children from the FARMFLORA birth cohort (N = 65), of whom 28 (43%) lived on a dairy farm and 40 (62%) had pets, provided fecal samples at intervals from 3 days to 18 months of age. Gut microbiota composition was characterized using quantitative microbial culture of various typical anaerobic and facultatively anaerobic bacteria, with colonization rate and population counts of bacterial groups determined at the genus or species level. Allergy was diagnosed at three and eight years of age by experienced pediatricians. Generalized estimating equations were used to identify associations between farm residence or pet ownership, gut microbiota development and allergy. Adjustments were made for important potential confounders.

Results
Growing up on a farm was associated with a higher ratio of anaerobic to facultative bacteria in the first week, smaller Escherichia coli populations in colonized children in the first months of life and less frequent colonization by Clostridioides difficile at 12 months of age. Having pets in the household was associated with more frequent colonization by Bifidobacterium, Lactobacillus and Bacteroides in the first months. A higher ratio of anaerobic to facultative bacteria at one week of age, early colonization by Bifidobacterium, Lactobacillus and Bacteroides, and reduced carriage of C. difficile at 4–12 months of age all correlated negatively with subsequent allergy diagnosis.

Conclusions
Our findings indicate that lower rates of allergy in children growing up on farms or with pets may be related to early establishment of typical anaerobic commensals in their gut microbiota. However, further studies are needed to validate our observations in this small birth cohort study.