bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE RELATION BETWEEN HELICOBACTER PYLORI SEROPOSITIVITY AND IRON DEFICIENCY ANEMIA IN IRAQ-KURDISTAN-SULAIMANI CITY
Authors: Rashid Nawshirwan , Ahmed Fidan , Abdullah Basil , Yassin Ahmed , Al-Ani Mouroge 
Published: June 2018

Background
Iron deficiency is the most common cause of anaemia worldwide and is seen in general practice. The cause of iron deficiency anemia changes in different age groups, whether due to blood loss, gastrointestinal causes or increase in body demand for iron.
Objectives
This study was designed to determine any relation between Helicobacter pylori positive subjects serologically in Sulaymaniyah city/Iraqi Kurdistan with Iron deficiency anemia.
Patients and Methods
The current study enrolled one hundred twenty female volunteers (eighty female with positive H. pylori serology, either both or any one of IgG & IgM positive) and forty subjects with negative serology. Then, contributors divided to four groups according to the age. H. pylori was detected serologically by using anti-H. pylori IgG and IgM antibodies ELISA kit.
Results
Hemoglobin level, mean corpuscular volume, white blood cells, platelets counts, serum ferritin and total iron binding capacity, were measured. Hemoglobin level and mean corpuscular volume in all patients considerably decreased (P < 0.01) compared with all control groups. While, the outcome of white blood cells and platelets counts demonstrated no considerable changes in all patient groups compare with all control groups. Serum ferritin in all patient categories significantly reduced (P < 0.01) compared with all control groups. While, TIBC levels significantly raised in patient groups compare with control groups.
Conclusion
There is a relation between Helicobacter pylori positive serology and iron deficiency anemia in Kurdistan- Sulaimania city.
INSULIN-LIKE GROWTH FACTOR-1 AND BREAST CANCER RISK IN KURDISH WOMEN
Authors: Abdulla Parween , Ismael Bahez , Namiq Kadhim , Awrahman Zmnako , Sadiq Shanya 
Published: June 2018

Background
Insulin-like growth factor -1 (IGF-1) has mitogenic and antiapoptotic effects on breast cancer cells. High-circulating IGF-1 was found to be associated with increased risk of breast cancer in several previous epidemiological studies, mostly conducted in the Caucasian populations. Little is known about the association between IGF-1 and breast cancer in Kurdish women whose dietary habits and genetic basis differ considerably from their Caucasian counterparts. IGF-1 levels can vary substantially among individuals and have been shown to be regulated in part by diet, age, lifestyle and anthropometric indices. Nutrition and energy balance have an important influence on IGF-1 levels which are decreased in energy-restricted diets and transiently increased with intense physical activity. Despite the number of factors that can influence IGF-1 levels, it has been estimated that up to 60% of the variability has a genetic basis, also age have been shown in some studies to be an important factor. Determinants of IGF-1 levels within racial and ethnic groups are unclear.
Research Goal
To investigate the association between IGF-1 and breast cancer in Kurdish women.
Methods
a population-based case-control study was conducted to assess the associations of IGF-1 with breast cancer risk in Kurdish women. The study included 131 incidents of premenopausal ER (+) and PR(+) breast cancer patients diagnosed between June 2016 and March 2017 at Hiwa Cancer Hospital, Slemani, Kurdistan of Iraq and 130 age-matched controls selected randomly from the general population at Marital Screening Center/ Slemani General Hospital.
Results
The results showed no statistically significant differences exist between the case and control in this study.
Conclusion
We have investigated a lack of correlation between circulating IGF-1 levels and breast cancer among Kurdish women patients.
CONGENITAL LUMBAR HERNIA: A CASE SERIES STUDY
Authors: Ameen Nian , Mohammed Mohammed 
Published: June 2018

Background
Congenital lumbar hernia is a rare anomaly with only 45 cases reported in the English-language literature, usually presents since birth either isolated or, less commonly, in association with other congenital malformations.
Objectives
This study done to record the prevalence rate of this very rare congenital anomaly at Sulaimani province, with reviewing the important clinical and anatomical aspects, along with the current surgical management of this malformation.
Methods
A case series study on just four cases presented over period of 10 years (May 2007 to June 2017), data were collected regarding the age at presentation, sex, associated anomalies, surgical management, and outcome, with measuring the prevalence rate.
Results
During the study period only four patients were recorded to have congenital lumber hernia. Male to female ratio was 1:1. All of them presented during infancy, with unilateral, and right sided CLH. One female presented with recurrence after a previous surgical correction. Lumbocostvertiberal syndrome was an associated anomaly in a female patient; bilateral undescended testes in a male patient. Three cases were managed with open surgical repair; without post operative morbidity and mortality. The recurrent case’s father declined further surgery.
Conclusion
CLH is a rare condition. The diagnosis is usually clinical. Due to the high frequency of associated congenital anomalies, a proper physical examination supplemented by plain X-ray and US study is important in every case. The treatment is surgical repair as soon as possible. There is a high chance of recurrence if big defect not corrected with meshplasty.
MITOCHONDRIAL ENZYMES CORRELATION WITH BREAST CANCER CLINICOPATHOLOGICAL PARAMETERS/ A STUDY IN SULAIMANI CITY-IRAQ
Authors: Yasseen Hadeel , Sahib Rawand , Ezzaddin Shahow 
Published: June 2018

Background
Thousands of researches are done for breast cancer, but still cancer epithelial cells relationship with the surrounding stromal cells is a great topic for researchers which is termed the tumor microenvironment.
Objectives
This study is designed to confirm that presence of the two main mitochondrial enzymes that act in ketone bodies production and utilization and their correlation with the clinicopathological parameters and tumor aggressiveness.
Materials and Methods
This cross sectional study was carried out in Iraq in which 40 selected cases of breast invasive ductal carcinoma not otherwise specified were stained immunohistochemically for two mitochondrial enzymes; HMGCS2 and ACAT1involved in ketone bodies production and utilization respectively and correlate their positivity with clinicopathological parameters of the breast cancer as patient’s age, estrogen and progesterone receptors, HER2, molecular types, tumor grade and lymph node metastasis.
Results
Out of 40 cases, 50% are in the age range of 41-50 years. Grade I seen in 7%, grade II in 23% and grade III in 70% of cases. Regarding lymph node status, 10% are N2 while 28% are N3. ACAT1 shows stromal significant positivity with N3 only (P. = 0.01). HMGCS2 shows a highly significant epithelial positivity with N2 (P. = 0.004) and a significant stromal positivity with low grade tumors (P. = 0.04).
Conclusion
No significant correlation between ketone bodies production or utilization with the studied clinicopathological parameters apart from tumor grade and lymph node status, indicating that aggressive and metastatic tumors are more capable of self dependence for feeding themselves with ketone bodies.
RISK FACTORS OF COLORECTAL CANCER IN SULAIMANI CITY
Authors: Hassan Mohammed , Ismail Kameran , Ramzi Zhian , Al-Hadithi Tariq 
Published: June 2018

Background
The risk of developing colorectal cancer is influenced by both environmental and genetic factors. Globally, colorectal cancer is the third most commonly diagnosed cancer in males and the second in females.
Objectives
This study was conducted to determine the risk factors of colorectal cancer in a sample of colorectal cancer patients in Sulaimani city.
Methods
A case-control study was carried out between December, 2014 and March, 2016. The cases were interviewed in Hewa hospital in Sulaimani city, which is the only health institution dealing with cancer patients in the city. A sample of 200 cases whom diagnosed and registered at the hospital was selected. Those cases were compared with 400 controls free from cancer matched in age (± 2 years) and gender. Controls were collected from patients attending Karezawshk and Xabat public clinics.
Results
Patients with colorectal cancer have a mean ± SD age of 53.85 ± 15.9 years (ranged from 18 to 90 years) and the controls have a mean ± SD age of 53.69 ± 13.7 years (ranged from 19 to 87 years). Male: female ratio was 1.1:1. Logistic regression analysis revealed that there are positive statistical significant associations of colorectal cancer with family history of CRC (OR=8.489, 95% CI=3.285-21.941), smoking (OR=3.392, 95% CI=1.774-6.485), overweight and obesity (OR=6.034, 95% CI=3.386-10.755), drinking of carbonated beverages (OR=5.822, 95% CI=3.286-10.314) and canned juice (OR=3.448, 95% CI=1.972-6.028). However, negative statistical significant association between colorectal cancer and practicing exercise (OR=0.535, 95% CI= 0.290-0.987) and drinking of fresh juice (OR=0.283, 95% CI=0.163-0.491) was detected.
Conclusion
The most common risk factors for colorectal cancer are family history of colorectal cancer, smoking, overweight, obesity, drinking of carbonated beverages, and canned juice, while practicing exercise and drinking of fresh juice are decreasing the risk for colorectal cancer.
Conversa com Aldyr Schlee (parte II): a criação da camisa canarinho e seu recente uso político [c/ áudio]
Authors: Guimarães Gustavo Cerqueira , Schlee Aldyr Garcia , Piazzi Giulia 
Published: June 2018

Entrevista com Aldyr Schlee, escritor, jornalista, professor e desenhista, criador do uniforme da seleção brasileira de futebol, em 1953, realizada por Gustavo Cerqueira e editada por ele, em parceria com Giulia Piazzi. Neste diálogo do escritor com a revista FuLiA / UFMG, o foco é a criação do desenho da camisa canarinho e seu recente uso político nas manifestações populares, vinculadas ao golpe. Áudios: https://soundcloud.com/user-530005952/schlee-sobre-a-criacao-da-camisa-canarinho.https://soundcloud.com/user-530005952/trecho-da-conversa-com-aldyr-schlee-parte-ii-a-criacao-da-camisa-canarinho.
CARACTERIZAÇÃO DE AMINOÁCIDOS NA Bertholletia excelsa: VIABILIDADE NUTRICIONAL PARA INCORPORAÇÃO NA DIETA DE FILHOTES DE PEIXE-BOI DA AMAZÔNIA EM CATIVEIRO
Authors: BARBOSA Paula de Sousa , MACHADO Olga Lima Tavares , SILVA Vera Maria Ferreira da , Junior Geraldo PEREIRA , ARAÚJO Jucélia Da Silva 
Published: June 2018

<p align="center">A maioria dos filhotes de <em>Trichechus inunguis</em> órfãos que chegam aos centros de pesquisa e reabilitação é lactante. Essa condição dificulta o processo de reabilitação, sendo necessário oferecer uma dieta láctea artificial adequada. Com o intuito de incrementar o teor de aminoácidos no sucedâneo lácteo buscou-se dentre os alimentos habitualmente amazônicos um ingrediente capaz de fornecer os nutrientes necessários para potencializar o sucedâneo utilizado, sendo facilmente adquiro, apresentar alto valor biológico, rápida manipulação, perecibilidade reduzida e baixo custo de obtenção. Dentre os alimentos que preenchem esses pré-requisitos, destaca-se a castanha-do-Brasil. Avaliou-se neste estudo a viabilidade nutricional em termos de aminoácidos da <em>Bertholletia excelsa, </em>para a possível suplementação no sucedâneo lácteo fornecido aos filhotes de peixe-boi da Amazônia em cativeiro. As amêndoas foram descascadas, maceradas e em seguida foi pesado 27 mg, digerido em HCl 6 M, aquecido a 150 <sup>o</sup>C por 90 minutos e analisado por Cromatografia Líquida de Alta Eficiência por troca iônica. Os resultados demonstraram uma concentração elevada de aminoácidos não essenciais, dentre eles arginina e ácido glutâmico + glutamina. Os aminoácidos em menor concentração foram prolina, alanina e tirosina. Dentre os aminoácidos essenciais, a valina e a leucina apresentaram as maiores concentrações, entretanto os aminoácidos menos abundantes foram à histidina, isoleucina. Os demais aminoácidos apresentaram teores equivalentes na análise da composição em aminoácidos da castanha. Concluiu-se nesse trabalho que a castanha do Brasil é uma fonte potencial de enriquecimento nutricional na dieta láctea de filhotes de <em>T.inunguis</em> em cativeiro.</p>
EVENTOS ADVERSOS E DEMAIS INCIDENTES NO CUIDADO ESTÉTICO REALIZADO PELO BIOMÉDICO
Authors: VIANNA VIEIRA Kennya Kattllem , MENDES JÚNIOR Walter Vieira 
Published: June 2018

<p>A dimensão da qualidade “Segurança do Paciente” passou a ser conhecida após a publicação do relatório <em>To Err is Human</em> do <em>Institute of Medicine</em>, que expôs as consequências do cuidado inseguro. Objetivo: Identificar os eventos adversos e demais incidentes no cuidado estético que pode ser realizado pelo Biomédico. Materiais e Métodos: Revisão integrativa, consultando as bases de dados Pubmed, Lilacs e Scielo nos idiomas inglês, espanhol e português. Resultados: Foram selecionados 31 estudos com vários tipos de eventos adversos relacionados ao tratamento estético: infecção; queimadura de pele; disfunção de músculo; dano que obrigou a procura de serviço de emergência; deformidade e dor. Conclusão: A diversidade de eventos adversos encontrada neste estudo mostra a necessidade do tema segurança do paciente ser introduzido na graduação do Biomédico.</p>
TERAPIA ANTIRRETROVIRAL: UM COMPARATIVO ENTRE CARACTERÍSTICAS EPIDEMIOLÓGICAS DE PACIENTES PORTADORES DE HIV
Authors: SILVA Claudinei Mesquita da , JORGE Alex Sandro , MATZECH Jakeline Aparecida , PEDER Leyde Daiane de , HORVATH Josana Dranka , TEIXEIRA Jorge Juarez Vieira , BERTOLINI Dennis Armando 
Published: June 2018

<p>Introdução: Entre os anos de 1996 a 2012, o uso da TARV (terapia antirretroviral) evitou a morte de 6,6 milhões de pessoas com o Vírus da Imunodeficiência Humana (HIV)/Síndrome da Imunodeficiência Adquirida (aids) no mundo e seu uso é fundamental para controle da replicação viral, diminuindo a transmissibilidade e retardando o desenvolvimento da aids. Objetivos: Comparar as características epidemiológicas, clínicas e laboratoriais de pacientes portadores do vírus HIV/aids em relação ao uso da terapia antirretroviral. Materiais e Métodos: Estudo transversal e descritivo realizado com 1184 prontuários de pacientes com HIV/aids, atendidos no período de janeiro de 2005 a dezembro de 2014, em um centro de referência pertencente à 10<sup>a</sup> Regional de Saúde (RS) do Paraná (PR), Brasil. Resultados: Observou-se que os pacientes com faixa etária de 18 e 39 anos, com diagnóstico maior que 5 anos, solteiros, com menor tempo de educação, com um ou nenhum parceiro sexual são os que possuem maior adesão à TARV, porém a diferença não foi significativa quando comparada aos indivíduos que não estão em tratamento. Pacientes em terapia possuem maiores níveis de linfócitos T CD4+ e menores de carga viral. Conclusão: Nenhuma das características sociodemográficas dos indivíduos atuou como facilitador à adesão. Pacientes em uso da TARV possuem significativamente menor carga viral, comparados aos não aderentes, reforçando a importância do tratamento em pacientes portadores de HIV/aids.</p>
RELATO DE CASO: RESPOSTA COMPLETA COM QUIMIOTERAPIA DE SEGUNDA LINHA EM CÂNCER DE BEXIGA ESTADIO IV
Authors: FREITAS Carla Simone Moreira de , GONÇALVES Paula Fontes Passalini 
Published: June 2018

<p>O câncer de bexiga é a neoplasia mais comum do sistema urinário, sendo raro ocorrer casos de resposta completa a quimioterapia em tumores avançados, quando não realizado cirurgia com intuito curativo. Objetivo: relatar o caso de um paciente que apresentou resposta completa da neoplasia vesical em estadio IV após quimioterapia de 2ª linha. Metodologia: relato de caso. <strong></strong></p>
APENDICITE AGUDA EM GESTANTE DE 32 SEMANAS: RELATO DE CASO
Authors: RIOS Davi Muzi , VIEIRA Vitória Conrado , SILVA João Romário Gomes da , XIMENES Luciana , ALTOÉ Gisela Machado , CERQUEIRA Jocieli Locatelli , ARAÚJO Lucas Wilson Ferreira de 
Published: June 2018

<p>Incidindo em 1 dentre 1500 gestações anualmente, a apendicite constitui-se em emergência cirúrgica em nosso meio, sendo a indicação mais comum de cirurgia por condições não obstétricas durante a gestação. Pode apresentar clínica inespecífica, devido às alterações anatômicas e fisiológicas advindas com a gravidez. Auxiliando na investigação diagnóstica dispomos de exames laboratoriais, e de imagem, sendo a ultrassonografia a primeira escolha. O tratamento é realizado por meio de antibióticoterapia associado à apendicectomia, podendo ser por via laparoscópica ou por laparotomia. Apresenta baixa mortalidade materna, excetuando casos de perfuração apendicular. O risco de óbito fetal eleva-se nos casos de apendicite perfurada, peritonite generalizada ou abscesso. O presente estudo tem por objetivo relatar um caso de apendicite aguda ocorrido numa gestante de 32 semanas que fora internada na maternidade do Hospital São José do Avaí, Itaperuna-RJ. Será realizada breve revisão bibliográfica em livros conceituados, além de plataformas <em>online</em> como <em>Medline</em> e <em>Scielo</em>, acerca do tema em pauta, observando as características gerais desta patologia e as suas peculiaridades durante o período gestacional, além de análise da conduta tomada comparando com a literatura. Concluímos que a apendicite é uma patologia relativamente comum dentre as gestantes, que embora apresente diagnóstico dificultado, este deve ser sempre suspeitado em quadros de dores abdominais e devidamente excluídos ou confirmados com a utilização de exames adequados, pois o retardo no seu diagnóstico pode elevar o risco de perfuração do apêndice, com consequente aumento do risco de óbito fetal.</p><p><strong> </strong></p><p><strong>Palavras chave: </strong>gestação, apendicite, diagnóstico.</p>
SÍNDROME DE STEVENS-JOHNSON E NECRÓLISE EPIDÉRMICA TÓXICA: RELATO DE CASO
Authors: SOUZA Maria Cristina Almeida , CORREIA Ana Paula Santos , MAGRANI Gefson , CÔRTES JÚNIOR João Carlos Souza , CÔRTES Paula Pitta de Resende 
Published: June 2018

<p>A Síndrome de Stevens-Johnson (SSJ) e a Necrólise Epidérmica Tóxica (NET) são reações mucocutâneas agudas, caracterizadas por máculas eritematosas, localizadas principalmente no tronco e em membros proximais, que evoluem progressivamente para bolhas flácidas confluentes, levando ao destacamento epidérmico. As drogas são os principais agentes etiológicos. As complicações mais frequentes são a sepse, a ceratoconjuntivite, a hiper ou hipopigmentação da pele e as complicações oculares. Numerosos casos necessitam de internação em unidades de terapia intensiva. Manifestações clínicas da SSJ e da NET são descritas por meio de relato de caso de uma paciente atendida na Unidade de Pronto Atendimento (UPA), diagnosticada com Síndrome de Stevens Johnson, que posteriormente evoluiu para NET.</p><p> </p>
Comparison of femoral block and adductor canal block in the postoperative analgesia of patients undergoing arthroscopic knee surgery
Authors: KUCUR TÜLÜBAŞ Evrim , BOSTANCI İpek , SERTÇAKACILAR Gökhan , PEKTAŞ Yaser , EDİPOĞLU Erdem 
Published: June 2018

Objectives: The aim of the study was to compare adductor canal block and femoral nerve block in the
postoperative analgesia of patients undergoing elective arthroscopic knee
surgery with respect to opioid use and Visual Analogue Scale (VAS), which is a
unidimensional measurement of pain intensity. Method:. The study was
designed and conducted prospectively between April 2016 and November 2016 in a
tertiary care hospital but the results were evaluated retrospectively. Prior to
the induction of general anesthesia for knee surgery, (the first) 20
consecutive patients underwent femoral nerve block, and (the second) 20 consecutive
patients received adductor canal block. Patients receiving adductor canal block
for analgesia were referred to as Group A and patients receiving femoral nerve
block for analgesia were defined as Group F. Pain was evaluated using the VAS
score.The results were compared statistically. Results: Both the femoral
nerve block and adductor canal block groups showed similar results in terms of
VAS and opioid use (p &lt; 0.05). Conclusion: In the postoperative analgesia of patients undergoing elective arthroscopic knee
surgery, no difference was found between adductor canal block and femoral nerve
block in terms of opioid use and VAS scores.
Significance of thiol/disulphide homeostasis and ischemia modified albumin levels in chronic obstructive pulmonary disease
Authors: EROĞLU Oğuz , DİNDAR BADEM Nermin , BACCIOĞLU Ayşe , CÖMERTPAY Ertan , NEŞELİOĞLU Salim , EREL Özcan 
Published: June 2018

Objectives: The
severity of inflammation occurring during chronic obstructive pulmonary disease
(COPD) is closely associated with oxidative stress. The aim of this study was
to investigate the diagnostic value of Thiol/disulphide homeostasis (TDH) and
ischemia modified albumin (IMA) levels in evaluating oxidative stress in COPD
patients. Methods: This
prospective study was performed with COPD patients presenting to the Kırıkkale
University Hospital and with healthy volunteers. Subjects’ demographic data
(age, sex, body mass index, and smoking status), native thiol (NT), total thiol
(TT), disulphide (Ds), IMA levels and Ds/NT, Ds/TT and NT/TT ratios were
recorded. Statistical analysis was performed with SPSS 21.0 software. Results: One hundred ninety
subjects were enrolled in the study, 141 COPD patients and 49 healthy
volunteers. No difference was determined between the patient and control groups
in terms of age, sex or body mass index. The antioxidant markers; NT and TT
levels and NT/TT ratio were significantly lower in the patient group compared
to the control group (p &lt; 0.001, p &lt; 0.001, and p
&lt; 0.003, respectively). The oxidant markers; IMA levels and Ds/NT and Ds/TT
ratios were significantly higher in the patient group (p = 0.006, p
= 0.003, and p = 0.003, respectively). Significant negative correlation
was determined between antioxidant and oxidant parameters. Sensitivity values
were NT: 87.2%, TT: 83.3%, Ds/NT ratio: 68.1%, Ds/TT ratio: 68.1%, and IMA:
77.8%. Conclusions: TDH was
impaired in favor oxidants in COPD patients. TDH parameters and IMA can be used
to monitor oxidative stress emerging in COPD.
How can we Engineer Stock Markets like NSEIL with BSE SENSEX index data using String Theory
Authors: Mallick Soumitra 
Published: June 2018

<span class="fontstyle0">This paper considers the problem of sustainably developing<br />stock exchanges like NSEIL and measurable index systems like BSE SENSEX by developing strategies to achieve sales volume which achieve optimal<br />growth rates. Experimental data on BSE SENSEX and Companies over time<br />are used which closely mimics now active NSEIL. This requires consideration<br />of consumer choice in intertemporal markets with endogenous stock market<br />products. A sequence of five steps is derived to characterize the venturing<br />technology which will achieve such desired stock market sales volume with<br />fixed prices and hence the optimal growth rate. It is derived how String Theory is sufficient to build such stock markets in value and volumes by using<br />depositories. </span>