bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visas and Non-discrimination
Authors: den Heijer Maarten 
Published: January 2019

Abstract
The article examines whether the EU visa policy discriminates on racial or religious grounds. That the EU’s selection of countries whose nationals are subject to the visa obligation strongly correlates with global ethnic and religious demarcations fuels concerns about discrimination. The article juxtaposes the standards that have evolved in European non-discrimination law for justifying disparate racial and religious effects of immigration policies with the legislative history of the Visa list regulation. It argues that the progressive refinement of visa liberalisation dialogues by the European Commission including benchmarks on risks associated with visa travel provides no basis for allegations that current decision-making is based on ulterior motives. However, the placement of the large majority of countries on the ‘black list’ dates from the intergovernmental Schengen era and has never been properly justified. The article recommends to rectify this omission and to fundamentally rethink the balancing of the positive and negative criteria for the visa obligation.
Reciprocal Interactions Between Audition and Touch in Flutter Frequency Perception
Authors: Convento Silvia , Wegner-Clemens Kira A. , Yau Jeffrey M. 
Published: January 2019

Abstract
In both audition and touch, sensory cues comprising repeating events are perceived either as a continuous signal or as a stream of temporally discrete events (flutter), depending on the events’ repetition rate. At high repetition rates (>100 Hz), auditory and tactile cues interact reciprocally in pitch processing. The frequency of a cue experienced in one modality systematically biases the perceived frequency of a cue experienced in the other modality. Here, we tested whether audition and touch also interact in the processing of low-frequency stimulation. We also tested whether multisensory interactions occurred if the stimulation in one modality comprised click trains and the stimulation in the other modality comprised amplitude-modulated signals. We found that auditory cues bias touch and tactile cues bias audition on a flutter discrimination task. Even though participants were instructed to attend to a single sensory modality and ignore the other cue, the flutter rate in the attended modality is perceived to be similar to that of the distractor modality. Moreover, we observed similar interaction patterns regardless of stimulus type and whether the same stimulus types were experienced by both senses. Combined with earlier studies, our results suggest that the nervous system extracts and combines temporal rate information from multisensory environmental signals, regardless of stimulus type, in both the low- and high temporal frequency domains. This function likely reflects the importance of temporal frequency as a fundamental feature of our multisensory experience.
Northeast Atlantic Storm Activity and Its Uncertainty from the Late Nineteenth to the Twenty-First Century
Authors: Krueger Oliver , Feser Frauke , Weisse Ralf 
Published: January 2019

AbstractGeostrophic wind speeds calculated from mean sea level pressure readings are used to derive time series of northeast Atlantic storminess. The technique of geostrophic wind speed triangles provides relatively homogeneous long-term storm activity data and is thus suited for statistical analyses. This study makes use of historical air pressure data available from the International Surface Pressure Databank (ISPD) complemented with data from the Danish and Norwegian Meteorological Institutes. For the first time, the time series of northeast Atlantic storminess is extended until the most recent year available, that is, 2016. A multidecadal increasing trend in storm activity starting in the mid-1960s and lasting until the 1990s, whose high storminess levels are comparable to those found in the late nineteenth century, initiated debate over whether this would already be a sign of climate change. This study confirms that long-term storminess levels have returned to average values in recent years and that the multidecadal increase is part of an extended interdecadal oscillation. In addition, new storm activity uncertainty estimates were developed and novel insights into the connection with the North Atlantic Oscillation (NAO) are provided.
Design and Preliminary Testing of the Volcanic Ash Plume Receiver Network
Authors: Rainville Nicholas , Palo Scott , Larson Kristine M. , Mattia Mario 
Published: January 2019

AbstractThe presence of volcanic ash in the signal path between a GPS satellite and a ground-based receiver strongly correlates with a decrease in GPS signal strength. This effect has been seen in data collected from GPS sites located near active volcanoes; however, the sparse placement of existing GPS sites limits the applicability of this technique as an ash plume detection method to relatively few well-instrumented volcanoes. This deficiency has motivated the development of a low-cost distributed sensor system based on navigation-grade GPS receivers, which can take advantage of attenuated GPS signals to increase the quality and availability of real-time ash plume observations during an eruption. This GPS-based system has been designed specifically to meet remote sensing needs while operating autonomously in difficult conditions and minimizing on-site infrastructure requirements. Prototypes of this system have undergone long-term testing and the data collected from this testing have been used to develop the additional processing steps necessary to account for the different behavior of navigation grade GPS equipment compared to the geodetic equipment used at existing GPS sites.
Treatment Outcomes of Angiolytic Laser-Assisted Glottoplasty in Patients With Sulcus Vocalis
Authors: Park Young Min , Lim Jae-Yol , Kang Min Seok , Choi Hong-Shik 
Published: January 2019

Objective: We have been performing glottoplasty using angiolytic laser, including pulsed dye laser (PDL) or potassium titanyl phosphate (KTP) laser, for the treatment of sulcus vocalis. In this study, we retrospectively reviewed the treatment results of sulcus vocalis patients who had undergone glottoplasty using angiolytic laser and evaluated the efficacy and safety of this surgical technique. Methods: From January 2008 to April 2016, 79 patients with sulcus vocalis who underwent angiolytic LASER-assisted glottoplasty were enrolled in the study. Results: Of the 79 patients who participated in this study, 55 were male, and 24 were female. PDL was used for glottoplasty in 68 patients, and KTP was used in the remaining 11 patients. Seventy-seven patients underwent surgery for bilateral vocal cord lesions, and only 2 patients underwent surgery for unilateral vocal cord lesion. After glottoplasty using angiolytic laser, most patients showed continuous improvement of the GRBAS (grade, roughness, breathiness, asthenia, strain) score and Voice Handicap Index score until 6 months after the operation. In addition, we observed improvement of objective voice indices such as noise to harmonic ratio, jitter, shimmer, and maximal phonation time postoperatively. Conclusions: Based on these results, we confirmed the efficacy and safety of glottoplasty using angiolytic laser in sulcus vocalis patients. Further studies are needed to confirm appropriate laser settings such as frequency of treatments and total energy delivered to the lesion. Also, multi-institutional studies are needed to confirm the efficacy and safety of the operation.
Predicting the Outcome of Unilateral Vocal Fold Paralysis: A Multivariate Discriminating Model Including Grade of Dysphonia, Jitter, Shimmer, and Voice Handicap Index-10
Authors: Lovato Andrea , Barillari Maria Rosaria , Giacomelli Luciano , Gamberini Lisa , de Filippis Cosimo 
Published: January 2019

Objectives: The aim of this study was to investigate if any clinical and phoniatric characteristics or quality-of-life measures could predict the outcome of unilateral vocal fold paralysis (UVFP) initially managed with speech therapy. Methods: Forty-six patients with UVFP were evaluated using laryngostroboscopy, the GIRBAS (grade, instability, roughness, breathiness, asthenia, and strain) scale, acoustic analysis, and the Voice Handicap Index-10 (VHI-10) questionnaire. Treatment was speech therapy according to a 3-phase protocol. The main outcome measure was incomplete vocal fold mobility 12 months after symptom onset. Univariate and multivariate modeling ( k-nearest neighbors model) were applied. Results: Fifteen patients had incomplete motion recovery 12 months after the onset of UVFP. On univariate analysis, time to diagnosis (0.01), global grade of dysphonia (0.018), jitter (0.01), shimmer (0.012), and VHI-10 score (0.006) were associated with the outcome of vocal fold paralysis. Using a k-nearest neighbors multivariate discriminating model, the best discrimination of UVFP outcome was achieved with 4 parameters: global grade of dysphonia 2 or 3, jitter > 2.46%, shimmer > 6.97%, and VHI-10 score > 13. The model’s misclassification rate for incomplete motion recovery was only 6%. The model showed sensitivity of 93% and specificity of 74%. Conclusions: Delayed diagnosis and speech therapy was associated with negative outcomes. Higher grade of dysphonia, jitter, shimmer, and VHI-10 score on initial phoniatric assessment may help clinicians in predicting the outcomes of UVFP patients.
Addressing Mental Health Literacy in a UK university campus population: Positive replication of a Canadian intervention
Authors: Hunt Sarah , Wei Yifeng , Kutcher Stan 
Published: January 2019

Objectives: Mental health concerns on university campuses are increasing in the UK. Improving mental health literacy (MHL) for students may be a useful part of an integrated approach to effectively address these concerns. This study evaluated a previously demonstrated effective Canadian campus MHL resource in a UK student sample. Design: This cross-sectional study conducted on one UK campus reports on student’s opinions about the impact of the Transitions (2nd edition) resource as well as applying a standard measure of MHL. Methods: Online survey using a convenience sample of students during semester 1 conducted over a 1-week period at a large UK university. Results: Use of Transitions (2nd edition) improved student self-reported mental health knowledge, decreased stigma and increased help-seeking intent. Significant ( p < .05) improvement in a standard MHL assessment was also found. Conclusions: These results suggest that the Transitions resource may be a helpful intervention in addressing student mental health in a UK university campus setting.
Evaluation of Gesture-Based In-Vehicle Interaction: User Experience and the Potential to Reduce Driver Distraction
Authors: Graichen Lisa , Graichen Matthias , Krems Josef F. 
Published: January 2019

Objective: We observe the effects of in-vehicle system gesture-based interaction versus touch-based interaction on driver distraction and user experience. Background: Driver distraction is a major problem for traffic safety, as it is a contributing factor to a number of accidents. Visual distraction in particular has a highly negative impact on the driver. One possibility for reducing visual driver distraction is to use new forms of interaction in the vehicle, such as gesture-based interaction. Method: In this experiment, participants drove on a motorway or in a city scenario while using touch-based interaction or gesture-based interaction. Subjective data, such as acceptance and workload, and objective data, including glance behavior, were gathered. Results: As a result, participants rated their subjective impressions of safe driving as higher when using gesture-based interaction. More specifically, acceptance and attractiveness were higher, and workload was lower. The participants performed significantly fewer glances to the display and the glances were much shorter. Conclusion: Gestures are a positive alternative for in-vehicle interaction since effects on driver distraction are less significant when compared to touch-based interaction. Application: Potential application of this research includes interaction design of typical in-vehicle information and entertainment functions.
Machine Learning to Predict Delays in Adjuvant Radiation following Surgery for Head and Neck Cancer
Authors: Shew Matthew , New Jacob , Bur Andrés M. 
Published: January 2019

ObjectiveTo apply a novel methodology with machine learning (ML) to a large national cancer registry to help identify patients who are high risk for delayed adjuvant radiation.Study DesignObservational cohort study.SettingNational Cancer Database (NCDB).Subjects and MethodsA total of 76,573 patients were identified from the NCDB who had invasive head and neck cancer and underwent surgery, followed by radiation. The model was constructed from 80% of the patient data and subsequently evaluated and scored with the remaining 20%. Permutation feature importance analysis was used to understand the weighted model construction.ResultsA total of 76,573 patients met inclusion and exclusion criteria. Our ML model was able to predict whether patients would start adjuvant therapy beyond 50 days after surgery with an overall accuracy of 64.41% and a precision of 58.5%. The 2 most important variables used to build the model were treating facility and urban versus rural demographics.ConclusionStatistics can provide inferences within an overall system, while ML is a novel methodology that can make predictions. We can identify patients who are “high risk” for delayed radiation using information from >75,000 patient experiences, which has the potential for a direct impact on clinical care. Our inability to achieve greater accuracy is due to limitations of the data captured by the NCDB, and we need to continue to identify new variables that are correlated with delayed radiation therapy. ML will prove to be a valuable clinical tool in years to come, but its utility is limited by available data.
Mental Health and Happiness: Evidence From the U.S. Data
Authors: Makki Nazgol , Mohanty Madhu S. 
Published: January 2019

The current study examines the role of poor mental health characterized by depression in the determination of an individual’s happiness measured by self-satisfaction and job satisfaction. Using two samples from the National Longitudinal Survey of Youth, 1979 (NLSY79) and following an ordered probit approach, the study demonstrates that, other variables held constant, an individual suffering from mental depression is likely to have lower levels of self-satisfaction and job satisfaction than those with better mental health. The significance of this variable in both self-satisfaction and job satisfaction regressions indicates that metal health status is an important covariate of an individual’s overall well-being, and should not, therefore, be omitted when estimating relevant happiness equations. JEL Classification Codes: A12, J28, Z13
Expression of vitamin D receptor in renal tissue of lupus nephritis and its association with renal injury activity
Authors: Sun J , Zhang S , Liu J S , Gui M , Zhang H 
Published: January 2019

Objective Vitamin D receptor (VDR) has potent anti-inflammatory activities. VDR gene polymorphism has been linked with systemic lupus erythematosus (SLE). However, its expression in the kidney has not been evaluated. This study aimed to investigate the relationship between VDR expression and renal pathology as well as clinical manifestations in lupus nephritis (LN). Methods A total of 20 renal biopsy specimens from 35 patients with LN were classified according to the International Society of Nephrology/Renal Pathology Society 2003 LN-type standards pathological type, and the activity index and chronicity index were determined. Five normal renal tissue samples were obtained from surrounding areas distal to nephronophthisis or renal tumors (>2 cm). The expression of VDR was assessed by immunohistochemistry. The relationships between VDR expression and histological injury index, proteinuria and Systemic Lupus International Collaborating Clinics (SLICC) renal activity scores were analyzed. Results As compared to the control group, the expression of VDR in the LN group was lower ( p < 0.001) and negatively correlated with activity index (r = –0.548, p = 0.012) but not with chronicity index (r = –0.277, p = 0.236). The expression of VDR in renal tissue was also associated with SLICC renal activity scores (r = –0.470, p = 0.037). Conclusion The down-regulation of VDR expression in renal tissues of LN patients was negatively correlated with renal activity and injury severity.
Pharmacist-led telehealth disease management program for patients with diabetes and depression
Authors: Cohen Lisa B , Taveira Tracey H , Wu Wen-Chih , Pirraglia Paul A 
Published: January 2019

Introduction The aim of this study was to determine whether a pharmacist-led telehealth disease management program is superior to usual care of nurse-led telehealth in improving diabetes medication adherence, haemoglobin A1C (A1C), and depression scores in patients with concomitant diabetes and depression. Methods Patients with diabetes and depression were randomized to pharmacist-led or nurse-led telehealth. Veterans with type 1 or type 2 diabetes, an A1C ≥ 7.5%, diagnosis of depression, and access to a landline phone were invited to participate. Patients were randomized to usual care of nurse-led telehealth or pharmacist-led telehealth. Patients were shown how to use the telehealth equipment by the nurse or pharmacist. In the pharmacist-led group, the patients received an in-depth medication review in addition to the instruction on the telehealth equipment. Results After six months, the pharmacist-led telehealth arm showed significant improvements for cardiovascular medication adherence (14.0; 95% confidence interval (CI) 0.4 to 27.6), antidepressant medication adherence (26.0; 95% CI 0.9 to 51.2), and overall medication adherence combined (13.9; 95% CI 6.6 to 21.2) from baseline to six-month follow-up. There was a significant difference in A1C between each group at the six-month follow-up in the nurse-led telehealth group (6.9 ± 0.9) as compared to the pharmacist-led telehealth group (8.8 ± 2.0). There was no significance in the change in patient health questionnaire-9 (PHQ-9) and Center for Epidemiologic Studies Depression Scale (CES-D) from baseline to follow-up in both groups. Discussion Pharmacist-led telehealth was efficacious in improving medication adherence for cardiovascular, antidepressants, and overall medications over a six-month period as compared to nurse-led telehealth. There was no significant improvement in overall depression scores.
The educational gradient in premature cardiovascular mortality: Examining mediation by risk factors in cohorts born in the 1930s, 1940s and 1950s
Authors: Ariansen Inger , Strand Bjørn Heine , Kjøllesdal Marte Karoline Råberg , Steingrímsdóttir Ólöf Anna , Mortensen Laust Hvas , Stigum Hein , Graff-Iversen Sidsel , Næss Øyvind 
Published: January 2019

Aims Educational inequality in cardiovascular disease and in modifiable risk factors changes over time and between birth cohorts. We aimed to assess how cardiovascular disease risk factors mediate educational differences in premature cardiovascular disease mortality and how this varies over birth cohorts and sex. Methods We followed 360,008 40–45-year-olds born in the 1930s, 1940s or 1950s from Norwegian health examination surveys (1974–1997) for premature cardiovascular disease mortality. Cox proportional hazard and Aalen’s additive survival analyses provided hazard ratios and rate differences of excess deaths in participants with basic versus tertiary education. Results Relative educational differences in premature cardiovascular disease mortality were stable, whereas absolute differences narrowed from the 1930s to the 1950s cohorts; rate differences per 100 000 person years declined from 170 (95% confidence interval 117, 224) to 49 (36, 61) in men and from 60 (34, 85) to 23 (16, 29) in women. Cardiovascular disease risk factors attenuated rate differences by 69% in both cohorts in men, and in women by 102% in 1930s and 61% in 1950s cohorts. Smoking had the single strongest influence on the educational differences for men in all three cohorts, and for women in the two most recent cohorts. Conclusion Smoking appeared to be the driving force behind educational differences in premature cardiovascular disease mortality in the 1930s to 1950s birth cohorts for men and in the two recent birth cohorts for women. This suggests that strategies for smoking prevention and cessation might have the strongest impact for reducing educational inequality in premature cardiovascular disease mortality.
Tailoring in the digital era: Stimulating dialogues on health topics in collaboration with social media influencers
Authors: Lutkenhaus Roel O , Jansz Jeroen , Bouman Martine PA 
Published: January 2019

In today’s media landscape, audiences increasingly turn to online communities for media consumption and to exchange information about specific niche interests such as health-related topics. This calls for a segmented approach in which interventions are targeted at online communities, tailored to their specific cultures and health-related perceptions, and leverage the dynamics of conversation and social influence in online networks. Strategies drawn from the field of influencer marketing provide interesting opportunities to reach and engage with audiences in a personally relevant manner, including with those who may disagree with an intervention’s message. This article reflects on what health communicators might learn from influencer strategies and proposes digital methods to target and tailor health communication in the digital era. More concretely, we present methods to: (a) identify online communities engaging on a specific health issue; (b) map community specific cultures and health-related perceptions; and (c) identify influencers as potential collaboration partners. As such, we adopt a slightly different take on tailoring by putting the creative and cultural competences of social influencers central, and by aligning our methods with a media mapping protocol to create influencer strategies that are tailored to the cultures and health-related perceptions of multiple online audience segments. We illustrate the potential of these methods with a study of how vaccination is discussed among Dutch Twitter users.