bluuebunny/crossref_metadata_2025_split huggingface dataset:
QUANTIFICATION OF SONICATED IMPLANTS FROM PATIENTS WITH OSTEOARTICULAR IMPLANT INFECTIONS
Authors: Vidal Llanos Salar , Auñon Alvaro , García Antonio Blanco , Cañete Joaquín García , Parron Raul , Esteban-Moreno Jaime 
Published: November 2024

AimTo evaluate the bacterial counts of sonicatied implants in patients with osteoarticular infections. Various studies have demostrated the usefulness of sonication of retrieved implants in order to provide an accurate microbiological diagnosis. Although cutoff values for original sonicate counts have been established, the use of centrifugation may influence these valuesMethodA retrospective, single-center study, including sonication fluid samples from implants removed between January 2011 and October 2023, was performed. Patients were diagnosed with implant-associated infection based on the criteria available at the time of diagnosis. Osteoarticular implants were sonicated following the protocol described by Esteban et al. Sonicated fluid was centrifuged for 20 minutes at 3000 x g, and the sediment was resuspended in 5 mL of phosphate buffer solution. Ten µl of the sample were streaked onto each medium for quantitative culture. Bacterial counts exceeding 100,000 CFU/mL were considered as 100,000 CFU/mL for statistical analysis.ResultsThe study included 457 sonication fluid samples. Of these, 316 samples were from patients with prosthetic joint infection (PJI), with 26.3 % diagnosed with acute PJI and 73.7 % with chronic PJI. Additionally, 141 samples were from patients with osteosynthesis infection. The median CFU/ml in the sonication fluid was 40,000 CFU/mL (IQR 1,000 CFU/mL-100,000 CFU/mL). No statistically significant difference was observed between the different types of implants (prosthesis vs. osteosynthesis, p=0.218). A trend of higher counts was noted for acute PJI compared to chronic PJI (р=0.052). Most infections were monomicrobial, but 16.2% were polymicrobial. Statistically significant higher bacterial counts were observed in polymicrobial infections compared to monomicrobial infections (р<0.005). Among monomicrobial infections, no differences were found between Gram-negative and Gram-positive microorganisms (р=0.416). No differences were also found between joints (knee vs. hip) (p=0.353).ConclusionsSignificant variability was observed in the number of colonies detected in all samples, regardless of the type of implant, the number of microorganisms or the species identified. Higher counts were detected in polymicrobial infections, and a trend was also noted for higher counts in acute infections.
Evaluation of reliability generalization of Conner-Davison Resilience Scale (CD-RISC-10 and CD-RISC-25): A Meta-analysis
Authors: Wojujutari Ajele Kenni , Idemudia Erhabor Sunday , Ugwu Lawrence Ejike 
Published: November 2024

Background
Resilience, a critical multi-faceted construct in psychological research, is often measured using Conner-Davison Resilience Scale (CD-RISC-10 and CD-RISC-25). This reliability generalization (RG) meta-analysis delves into evaluate the level of reliability generalization estimate of both CD-RISC-10 and CD-RISC-25 in assessing resilience across diverse populations and settings.

Methods
A reliability generalization meta-analysis on the psychometric properties of CD-RISC-10 and CD-RISC-25 was conducted, encompassing 27 studies. The original versions’ psychometric properties were systematically retrieved from databases including PubMed, PsycINFO, Google Scholar, Web of Science, Science Direct, and Scopus, with a focus on studies published between 2018 and 2023. The study protocol, including the specific methods for the reliability generalization meta-analysis, was pre-registered in the Prospero database (registration number CRD42023479052). This pre-registration ensures transparency and minimizes the risk of bias in the study design and analysis.

Results
The analysis revealed a combined estimated overall estimate of Cronbach’s Alpha of 0.89 (95% CI [0.87, 0.91], z = 77.20, p < 0.05), indicating a high level of reliability for CD-RISC-10 and CD-RISC-25. CD-RISC-10 exhibited an overall estimate of Cronbach’s Alpha of 0.8732 (95% CI [0.85, 0.10], z = 69.81, p < 0.05), indicating a high level of reliability, while CD-RISC-25 also demonstrated an overall estimate of Cronbach’s Alpha of 0.8922 (95% CI [0.87, 0.91], z = 77.20, p < 0.001), indicating a high level of reliability. Furthermore, CD-RISC-10 displayed commendable reliability (ωα+ = 0.86), slightly lower compared to the impressive reliability of CD-RISC-25 (ωα+ = 0.89), with a significant difference (t = 0.1159, p > 0.001). The mixed-effects model revealed a non-significant moderating effect of the CD-RISC language version on reliability estimates (coefficient = -0.0017, p <0.05).

Conclusion
The results affirm the high overall reliability of both CD-RISC-10 and CD-RISC-25, with CD-RISC-25 exhibiting a slightly superior level. The non-significant moderating effect of language version suggests that the psychometric properties of these scales remain robust across different linguistic adaptations. These findings enhance our understanding of the CD-RISC scales, providing practitioners, researchers, and clinicians valuable insights for informed scale selection in diverse contexts. The commendable reliability of both scales underscores their utility in assessing and promoting resilience across varied populations and settings. Future research should explore specific contexts, demographics, and applications, enhancing their utility for diverse populations and settings.
Global prevalence of anemia in displaced and refugee children: A comprehensive systematic review and meta-analysis
Authors: Teketelew Bisrat Birke , Chane Elias , Angelo Abiy Ayele , Tamir Mebratu , Cherie Negesse , Nigus Mesele , Mulatie Zewudu , Berta Dereje Mengesha 
Published: November 2024

Background
Anemia due to living condition disproportionally affects the global refugee children. Nutritional deficiency particularly iron deficiency is the primary causes of anemia. Hence, we conducted a systemic review and meta-analysis on the prevalence of anemia among refugee children.

Methods
We searched systematically all relevant studies on the prevalence of anemia among refugee children including under the age of 18 years, which were conducted between 2009 and 2023 in English from PubMed, Embase, Scopus, Cochran library and other gray literatures such as google scholar. Two researchers independently screened articles based on their title and abstract. The Joana Brigg’s Institute (JBI) checklist was used to assess the quality of studies. Random effect model was utilized to calculate the pooled estimate of anemia. Higgins I2 statistics and Egger’s test were analyzed to check heterogeneity and publication bias, respectively. Subgroup analysis by continent, age group of the children and year of study was employed to identify the source of heterogeneity.

Result
A total of 14 studies were included in the final meta-analysis. Most of the studies were from Asian countries followed by African countries. The pooled prevalence of anemia among global refugee children was 36.54 with (95% CI: 23.79, 49.28). There was moderate level of heterogeneity between the studies (I2 = 68.91, P<0.001). The highest pooled prevalence of anemia in refugee children was reported in African, it was 56.1%, whereas the lowest pooled prevalence of anemia was in N. America, it was 12.66%. The prevalence of anemia was highest (53.88) in studies done among under-five refugee children.

Conclusion
The global prevalence of anemia among refugee children is found to be moderate public health problem. Anemia prevalence is more common in African refugee children. Intervention and prevention for should be focused especially for refugees found in low- and middle-income countries.
Analysis of serum vitamin D and calcium levels in elderly patients with stable and unstable intertrochanteric fractures: A multi-center prospective study
Authors: Alijanpour Kamran , Afzal Sina , Alijanpour Abolhasan , Barati Hasan , Gholinia Hemmat , Tavassoli Mehdi 
Published: November 2024

Background
Hip fractures are highly prevalent in the elderly, with intertrochanteric (IT) fractures of the femur constituting about half of the fractures in this region. We aimed to evaluate the levels of serum calcium and vitamin D in patients with stable or unstable IT fractures to study their contribution to the severity of IT fracture.

Materials and methods
Using a prospective cross-sectional design, we enrolled patients with IT fractures admitted to two referral orthopedic centers in 2022. Unstable IT fracture was defined as those with reverse obliquity or a trans-trochanteric pattern of fracture, a large or comminuted posteromedial fragment, and subtrochanteric extension of the fracture. Serum 25 (OH) vitamin D and calcium levels were the main study variables assessed by lab tests and compared among the two study groups: stable and unstable IT fractures.

Results
A total of 286 patients with a mean age of 70.5 ± 7.3 years and a female predominance (60.4%) were included in the final analysis. Among the patients, 139 (48.6%) had stable IT fractures, and 147 (51.4%) had unstable IT fractures. The mean serum level of vitamin D was significantly higher in the stable group (30.3 ± 7.0) compared to the unstable group (26.5 ± 6.1) (P-value = 0.007). Increasing age was associated with a decreasing level of serum vitamin D; however, the association was weak and not statistically significant (P-value = 0.319). The mean serum calcium level was higher among stable cases (8.6 ± 0.7) compared to unstable cases (8.4 ± 0.9); however, the difference was not statistically significant (P-value = 0.540). Vitamin D and calcium levels were almost similar among males and females.

Conclusion
Lower levels of serum vitamin D were significantly associated with unstable IT fractures, and supplementation with this element might prevent severe fractures of this type and other fragility hip fractures.
Work-related stress among financial professionals: The impact of age, work experience and education
Authors: Kutebayev Talgat , Utaliyeva Zhanna , Sautenkova Marina , Aizhanova Gulnara 
Published: November 2024

Objective
The aim of this study was to investigate the differences in the level and sources of work-related stress among financial professionals regarding age, work experience, and educational level.

Methods
A cross-sectional research design was employed among 702 financial professionals in Kazakhstan who worked in different corporate and government organizations. Data on work-related stress were collected via online questionnaires using the Job Stress Survey (JSS).

Results
The results showed that young financial professionals experienced higher stress than older professionals due to the lack of opportunity for advancement. Moreover, the study findings revealed that less experienced financial professionals reported higher levels of stress than more experienced professionals due to the meeting deadlines and conflicts with other departments. The study also found that financial professionals with a postgraduate degree stressed more than professionals with an undergraduate degree on major JSS scales. Furthermore, financial professionals with a postgraduate degree experienced higher stress due to the assignment of disagreeable duties, working overtime, lack of opportunity for advancement, inadequate support by supervisor, dealing with crisis situations, lack of recognition for good work, difficulty getting along with supervisor, insufficient personnel to adequately handle an assignment, lack of participation in policy-making decisions, inadequate salary, excessive paperwork, and covering work for another employee than professionals with undergraduate and vocational degrees.

Conclusion
The findings of this study provide valuable insights for organizations to eliminate and alleviate work-related stress.
Unikatowe znalezisko przyborów kupieckich z Jaryszek. Przyczynek do studiów nad rolą peryferycznego otoczenia Poznania we wczesnym średniowieczu
Authors: Waszczuk Kamilla , Żychliński Daniel , Kuzioła Aneta 
Published: November 2024

During research at an early medieval site located 11 km away from Poznań’s Ostrów Tumski (Cathedral Island), a set of tools for weighing bullion was found, consisting of balance scales, 10 standardised weights, and a decorative copper alloy necklace clasp. Due to the state of preservation, mechanical features and the place of uncovering, these artefacts prompted a multi-faceted analysis of the possible reasons why such valuable objects were left in one of the sites of the extensive settlement, located by the Kopel and Michałówka valley. As a result, new evidence has been obtained on the links between the main strongholds of the Polish state and the subordinate settlements, as well as on the existence of possibilities of communication between them (hitherto unconsidered) and on local variations in social stratification. At the same time, the need to carry out methodical research on archaeological sites and to exercise conservation protection over them was stressed, in the face of a threat of losing ample interpretative opportunities when the sites become victims of illegal forms of exploration
Property Rights, Fossil Fuel Imports, and Climate Change
Authors: Garcia-Gibson Francisco 
Published: November 2024

Abstract
Shmuel Nili claims that when a country buys fossil fuels from dictatorships it becomes complicit with property rights violations in those dictatorships. Thus, Nili argues, people who have a strong commitment to property rights should support a ban on fossil fuel imports from dictatorships, and a transition to renewable energy. This article critically discusses Nili’s argument. The argument fails to consider competing moral reasons that some people may have to oppose a ban on fossil fuel imports from dictatorships, such as moral preference for family and compatriots. The argument also mistakenly assumes that renewable energy would be overwhelmingly economically attractive when fossil fuel imports are forbidden, and that switching to renewable energy would not involve importing stolen goods too. The article ends more propositively, by elaborating an alternative argument that Nili dismisses too quickly, and which may help persuade those who are strongly committed to property rights of transitioning to renewable energy: the argument that transitioning would help avoid violating those rights through contributions to harmful climate change.
Past, Present, and Future: A Reply to Heyd and Benbaji
Authors: Zreik Raef 
Published: November 2024

Abstract
In this paper I respond to the replies of David Heyd and Yitzhak Benbaji to my paper ‘War and Self-Defense: Reflections on the War on Gaza’. Heyd’s relativizing of narrative overlooks the epistemic hierarchy among narratives and their important role in establishing facts, and his claim that Israel’s history is not colonialist in character fails because it is based on a misunderstanding of colonialism in general and settler colonialism in particular. Historically, I outline how Benbaji’s appeal to the legal status of the Mandate is problematic, because it ignores the illegitimacy of the legal regime behind it, such that accepting his argument would be to legitimize colonialism. Theoretically, I defend the view contrary to Benjabi, that instead of their being a moral tie between two equal sides, the Palestinians have always had fundamental legal and moral rights that the Zionist project violated ab initio and continues to violate.
Civic Friendship, the Burdens of Politics, and the Ethics of Attention
Authors: Kapelner Zsolt 
Published: November 2024

Abstract
In Philosophizing the Indefensible Shmuel Nili proposes strategic political theory as a productive and respectful manner for political philosophy to engage with unreasonable political views. One objection to his proposal he considers is that strategic political theory gives ‘excessive attention' to unreasonable views. In this paper I offer a perspective on this objection which Nili does not consider and which, I believe, has important consequences for his account. The strategic theorist pays engaged and respectful attention to unreasonable views for the sake of showing respect and upholding ties of civic friendship with unreasonable citizens. Yet such attention might inadvertently disrespect and damage ties of civic friendship with those disadvantaged by the indefensible policies of the unreasonable. I consider how this consideration bears on Nili’s argument for strategic theorizing based on the practical necessity to alleviate what he calls ‘the burdens of politics'.
Fosinopril inhibits Ang II-induced VSMC proliferation, phenotype transformation, migration, and oxidative stress through the TGF-β1/Smad signaling pathway
Authors: Chen Siqi , Ye Lingxiang 
Published: November 2024

Abstract
Fosinopril (FOS) is an angiotensin-converting enzyme inhibitor that can decrease angiotensin II (Ang II) formation, thereby reducing systemic vasoconstriction. This study investigated the impact of FOS on vascular smooth muscle cell (VSMC) phenotypic transformation in hypertension. Experiments using western blotting revealed that FOS inhibits the Ang II-induced downregulation of α-SMA and SM22α and the upregulation of OPN in VSMCs. In addition, CCK8 assays, EdU staining, and Transwell assays demonstrated that FOS reduces Ang II-induced increases in VSMC cell viability, proliferation, migration, and MMP2 and MMP9 expression. Moreover, immunofluorescence and ELISA experiments showed that FOS suppresses Ang II-induced increases in ROS levels, NAD(P)H activity, and NOX2 and NOX4 expression in VSMCs. Western blotting also indicated that FOS inhibits Ang II-induced increases in TGF-β1 and p-Smad2/3 expression in VSMCs. Finally, FOS mitigates Ang II-induced VSMC proliferation, phenotypic transformation, migration, and oxidative stress by inhibiting the TGF-β1/Smad signaling pathway. In conclusion, these results suggest that FOS could be effective in managing vascular diseases, including hypertension.
Review: Dicranostigma leptopodum: A peculiar plant of Papaveraceae
Authors: Tian Ye , Geng Yang , Zhang Yaolei , Zhao Zeyue , Ruan Lihong , Zhang Chuanbao 
Published: November 2024

Abstract

Dicranostigma leptopodum (Maxim.) Fedde, an intriguing plant of the Papaveraceae family, exhibits numerous physiological activities, including antitumor, cytotoxic, immune-boosting, antibacterial, antioxidant, insecticidal, smooth muscle modulation, antiarrhythmic, fluorescent probe capabilities, as well as hypolipidemic and hypoglycemic effects. The plant’s diverse pharmacological actions are believed to be attributed to its rich reservoir of alkaloids distributed throughout the entire plant. This review encompasses an exploration of the chemical constituents, pharmacological activities, species distribution, extraction and separation methodologies, and content determination of D. leptopodum, aiming to contribute to its further advancement in medicinal development.
Renal microangiopathy and immune complex glomerulonephritis induced by anti-tumour agents: A case report
Authors: Guo Li , Hao Zhen-Zhen , Zhang Qian , Liu Qiu-Ju , Gao Yan , Ran Lei 
Published: November 2024

Abstract
A 60-year-old woman with bilateral lower extremity oedema for several days was admitted to the hospital on 21 November 2023. Previously, after receiving rectal cancer resection in February 2023, she had been receiving drug chemotherapy, during which she had normal urinalysis and renal function. However, 10 days before admission, after the drug regimen was adjusted to tislelizumab + fruquintinib, she developed bilateral lower extremity oedema with foamy urine; this was later extended to facial oedema. After a histologic examination of renal biopsy, it was judged as drug-induced glomerular microangiopathy (GMA) with focal segmental glomerulosclerosis-like lesions accompanied by immune complex-mediated glomerulonephritis. The condition was controlled by stopping the anti-tumour drug, lowering glucose with linagliptin, and providing renal protection with Nephritis Rehabilitation Tablets, and the patient recovered well at the follow-up visit after 6 months. This case may be GMA induced by tislelizumab or fruquintinib and was examined in this study.
The fourth moment of the Hurwitz zeta function
Authors: Heap Winston , Sahay Anurag 
Published: November 2024

Abstract
We prove a sharp upper bound for the fourth moment of the Hurwitz zeta function

ζ
⁢

(
s
,
α
)

\zeta(s,\alpha)

on the critical line when the shift parameter 𝛼 is irrational and of irrationality exponent strictly less than 3.
As a consequence, we determine the order of magnitude of the

2
⁢
k

2k

th moment for all

0
⩽
k
⩽
2

0\leqslant k\leqslant 2

in this case.
In contrast to the Riemann zeta function and other 𝐿-functions from arithmetic, these grow like

T
⁢

(

log
⁡
T

)

k

T(\log T)^{k}

.
This suggests, and we conjecture, that the value distribution of

ζ
⁢

(
s
,
α
)

\zeta(s,\alpha)

on the critical line is Gaussian.
Existence of three solutions for two quasilinear Laplacian systems on graphs
Authors: Pang Yan , Zhang Xingyong 
Published: November 2024

Abstract
We deal with the existence of three distinct solutions for a poly-Laplacian system with a parameter on finite graphs and a

(

p
,
q

)

\left(p,q)

-Laplacian system with a parameter on locally finite graphs. The main tool is an abstract critical point theorem in [G. Bonanno and S. A. Marano, On the structure of the critical set of non-differentiable functions with a weak compactness condition, Appl. Anal. 89 (2010), no. 1, 1–10]. A key point in this study is that we overcome the difficulty to prove that the Gâteaux derivative of the variational functional for poly-Laplacian operator admits a continuous inverse, which is caused by the special definition of the poly-Laplacian operator on graph and mutual coupling of two variables in system.
A data augmentation approach to enhance breast cancer detection using generative adversarial and artificial neural networks
Authors: Alawee Wissam H. , Al-Haddad Luttfi A. , Basem Ali , Al-Haddad Abdullah A. 
Published: November 2024

Abstract
Breast cancer is globally known to be a major health concern that necessitates advancements in detection and classification methods. This study introduces a machine learning-based approach for breast cancer diagnosis using benign and malignant mammograms of breast cancer. A two-hidden-layer artificial neural network (ANN) model was designed to categorize breast cancer from mammographic images. Prior to analysis, the images were subjected to a sophisticated data augmentation process that leveraged data denoising, contrast enhancement, and the application of a generative adversarial network (GAN). This multi-enhancement preprocessing enriched the quality of the images and transformed them into a format more amenable to analysis by vectorizing the pixel data. The methodology involved rigorous training of the ANN on input images, resulting in a significant improvement in the model’s ability to classify breast cancer accurately. Experimental results demonstrate a notable enhancement in classification performance, with an increase in accuracy ranging from 22.5 to 42.5% compared to traditional scans. The final model achieved an impressive accuracy rate of unity, which considered all stages of image processing, including normal, contrast-enhanced, denoised, and GAN-enhanced scans. The outcomes of this research underlined the effectiveness of data augmentation and ANN in medical imaging. Future innovations in breast cancer diagnostics are elaborated by the potential to improve early detection and patient outcomes. The robust offered methodology for breast cancer detection is considered to be a significant contribution to biotechnological fields of interest.