bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the impact of fibroblast proximity to a tumor on fibroblast extracellular vesicle production utilizing 3D bioprinted stromal models
Authors: Amens Jensen N. , Yang Jun , Hawthorne Lauren , Zorlutuna Pinar 
Published: December 2024

AbstractExtracellular vesicles (EVs) are an important carrier of cellular communication that are secreted from the cell. Different cells will produce EVs with different cargo such as cytokines, RNAs, or microRNAs (miRNA). EVs have been proven to play an important role in breast cancer tumorigenesis, progression, and metastasis. Although the role of cancer associated fibroblasts (CAFs), and EVs originated from them have been studied extensively, there is a lack in knowledge on the contribution of normal fibroblasts surrounding the tumor and their roles with respect to their proximity to the tumor. Here we investigate how the proximity of the tumor affects the EV production of the normal fibroblasts. We created stromal models by 3D bioprinting two different fibroblasts, normal human mammary fibroblasts (hMFs) and normal tumor adjacent fibroblasts (NTAF), within a collagen gel. After one week of culture, we isolated EVs from both the effluent media and the 3D stromal model, which were then characterized using nanoparticle tracking analysis (NTA), transmission electron microscopy (TEM), ELISA, zeta potential, and cytokine array analysis of the cargo. The EVs from each group were of consistent exosome size and displayed traditional exosome markers, however the EVs from different groups also displayed different cytokine profiles of their cargo, with the NTAF media group showing an upregulation of cytokines associated with breast cancer progression. After this, we used the EVs to treat breast cancer cells to investigate the effects the EVs from different tumor proximities have on the breast cancer cell behavior. The breast cancer cells treated with the NTAF groups had increased migration. Finally, we utilized a 3D breast tumor model to investigate the effects of the EVs on a tumor spheroid. Tumor spheroids treated with either NTAF EV groups showed increased proliferation, tumor radius, and local invasion. This study is the first to investigate the effect of proximity to a breast tumor on EV production and the first to utilize 3D bioprinting of stromal models specifically to obtain EVs. Overall, our results show that EVs from normal fibroblasts closer to a tumor produce EVs that promote breast cancer progression, regardless of the secretion location of the EVs. These cells have a distinct EV secretome different from normal human mammary fibroblasts, showing that the proximity to a tumor influences the normal fibroblasts surrounding the tumor.
Characteristics and HIV-related Engagement of Male Sexual Partners of Female Sex Workers in Sub-Saharan Africa (SSA): a Scoping Review
Authors: Maringwa Galven , Matambanadzo Primrose , Hargreaves James R. , Fearon Elizabeth , Cowan Frances M. 
Published: December 2024

ABSTRACTIntroductionUnderstanding the characteristics and behaviors of male sexual partners of female sex workers (FSWs) is crucial for comprehending the dynamics of HIV transmission. We aimed to explore and quantify the existing literature on male sexual partners of FSWs in SSA, where HIV prevalence is high and the dynamics of sex work are poorly understood. We focused on the proportions of men reporting sex with FSWs, along with their characteristics, HIV prevalence, and engagement with HIV services among the general population and specific subgroups.MethodsWe searched the literature in the EBSCOhost databases (Medline Complete, Global Health, and CINAHL). We included quantitative epidemiological peer-reviewed articles published in English between January 2010 and December 2023, following PRISMA guidelines for scoping reviews. The last search was performed on 09 October 2024. Eligible studies focused on men from the general population and subgroups of men who reported having sex with FSWs. The results were synthesized narratively to identify patterns and gaps in the literature.ResultsWe identified 2,067 articles and reviewed 15, including one meta-analysis. The general population meta-analysis and the articles among subgroups revealed variations in reporting sex with FSWs, differences in HIV prevalence, suboptimal HIV testing uptake, and inconsistent condom use. The proportion of general population men in SSA who had ever paid for sex was 8.5%, with a pooled HIV prevalence of 3.6% and 67.5% reported condom use at last paid sex. High-risk subgroups of men reported different rates of sex with FSWs, ranging from 6.6% to 74%. HIV prevalence also varied significantly, from 7.5% to 26%. Across these high-risk groups, suboptimal HIV testing uptake and inconsistent condom use were common, with no comparative data for men who did not have sex with FSWs.DiscussionMen who have sex with FSWs cannot be identified by specific characteristics. High-risk subgroups reported greater engagement with FSWs. Sex with an FSW was associated with higher HIV prevalence among men in the general population, with no data on subgroups. These findings highlight the need for tailored, occupation-specific interventions that address the unique needs of mobile and high-risk men.
A study on the capital accumulation system,
distribution regulation mechanism and stakeholder relationships from the
perspective of Marx’s theory of ground rent
Authors: Xie Di , Rong Ying 
Published: December 2024

Purpose
Ground rent has been playing a vital role in China’s economic and
social development, which has a clear practical logic. It is also necessary
to present the historical inevitability and institutional mechanisms that
realize this role of ground rent concerning its theoretical and historical
logic.

Design/methodology/approach
This paper draws on the theories of the French regulation school and the
social structure of accumulation theory to establish a preliminary
analytical framework. This paper explores the process of ground rent
formation under certain land institutional arrangements, as well as the
association between the capital accumulation system, the distribution
regulation mechanism and relevant stakeholder relationships. From the
perspective of historical materialism, the paper examines the functions of
ground rent in feudal and capitalist societies and their mapping association
between the capital accumulation system, distribution regulation mechanism
and stakeholders. This paper further investigates the inevitable trends in
the evolution of different social systems from the perspective of rent.
Additionally, based on Marx’s view on ground rent under socialism,
the paper elucidates the formation, types of rent and its engagement in
social production under the conditions of China’s socialist market
economy, identifying the inherent value orientation and distinct
institutional advantages.

Findings
Although considerable research has explored the reasons for the existence,
categories and functions of rent in a socialist market economy, there is a
relatively insufficient examination of its historical evolution and how it
influences real-world economic dynamics. Existing studies have primarily
focused on agricultural rent, lacking an in-depth analysis that puts the
behaviors of landowners, land operators and laborers in fundamental
contexts.

Originality/value
As China enters a new stage of development, it is imperative to improve the
public ownership of land from a new historical starting point, encourage the
rational use of ground rent leverage, and establish and enhance the capital
accumulation system, the distribution regulation mechanism and relevant
stakeholder relationships, enabling their more harmonious alignment with the
socialist market economy. The following effort should be made to ensure that
such actions will be put into place.
The thought of community with a shared future for
mankind and the construction of China’s international political
economy
Authors: Sun Jingyu 
Published: December 2024

Purpose
Central to this paper, Western international political economy cannot well
explain China’s peaceful development and its political and economic
ties with the outside world, and it is even more difficult to reflect the
characteristics of the times that the great changes unseen in a century and
socialism with Chinese characteristics have entered into a new era, which
are synchronously intertwined and mutually agitated. Constructing
China’s international political economy not only emphasizes the
Chinese perspective, Chinese discourse and Chinese narrative but also
examines the development trend and major problems facing the world from the
height of world history and applies the position, viewpoints and methods of
Marxist historical materialism to observe the times, interpret the times and
lead the times.

Design/methodology/approach
Looking back at the development of China’s international political
economy, from introducing Western international political economy to
increasingly emphasizing the Chinese perspective, Chinese discourse and
Chinese narrative, we analyze the distinctive features of China’s
international political economy from Western international political
economy.

Findings
The thought of community with a shared future for mankind is the latest
development and concentrated embodiment of Marxist thought on world history
in the 21st century, which gives China’s international political
economy a distinctive epochal, scientific and practical character,
stipulates the research stance and fundamental purpose, establishes the
research theme and main line and expands the research space for the
construction of Chinese international political economy.

Originality/value
The construction of China’s international political economy is not
only to create a “Chinese school” of international relations
but more importantly to construct a discourse and academic system of
China’s international political economy that can understand and grasp
the changes in the world, the times and history, providing academic support
for in-depth thinking and answering the question of “What is wrong
with the world? What should we do?” and contributing Chinese
wisdom.
A conservative degree adaptive HDG method for transient incompressible flows
Authors: Felipe Agustina , Sevilla Ruben , Hassan Oubay 
Published: December 2024

Purpose
This study aims to assess the accuracy of degree adaptive strategies in the context of incompressible Navier–Stokes flows using the high-order hybridisable discontinuous Galerkin (HDG) method.

Design/methodology/approach
The work presents a series of numerical examples to show the inability of standard degree adaptive processes to accurately capture aerodynamic quantities of interest, in particular the drag. A new conservative projection is proposed and the results between a standard degree adaptive procedure and the adaptive process enhanced with this correction are compared. The examples involve two transient problems where flow vortices or a gust needs to be accurately propagated over long distances.

Findings
The lack of robustness and accuracy of standard degree adaptive processes is linked to the violation of the free-divergence condition when projecting a solution from a space of polynomials of a given degree to a space of polynomials with a lower degree. Due to the coupling of velocity-pressure in incompressible flows, the violation of the incompressibility constraint leads to inaccurate pressure fields in the wake that have a sizeable effect on the drag. The new conservative projection proposed is found to remove all the numerical artefacts shown by the standard adaptive process.

Originality/value
This work proposes a new conservative projection for the degree adaptive process. The projection does not introduce a significant overhead because it requires to solve an element-by-element problem and only for those elements where the adaptive process lowers the degree of approximation. Numerical results show that, with the proposed projection, non-physical oscillations in the drag disappear and the results are in good agreement with reference solutions.
From reform to innovation: a review of Chinese auditing practices in a global context
Authors: Gui Carrie Q. , Lyu Meng , Zhang Joseph H. 
Published: December 2024

PurposeThis study aims to review and synthesize the burgeoning field of auditing research utilizing Chinese data. Over the past decades, there has been a remarkable rise in such research, driven by China’s abundant audit data, distinctive institutional features and enduring cultural influences. The purpose is to comprehensively review auditing studies featured in top-tier accounting journals, shedding light on the unique contributions made possible by Chinese data. By identifying key themes across domains, this paper aims to underscore the cultural and contextual disparities between China and Western countries, predominantly the USA, within the area of auditing.Design/methodology/approachThis study presents a systematic review of China-themed auditing research, primarily published in seven leading global accounting journals. The researchers conducted a comprehensive search of the websites of these journals, identifying relevant articles using search terms such as “China auditing,” “Chinese Stock Market and Accounting Research (CSMAR),” “institutional environment,” and “internal control.” After the initial search, 54 relevant articles were selected and reviewed. The study covers all China-specific auditing research, categorizing key themes into six areas to explore how scholars use Chinese data to address important auditing questions.FindingsThe findings reveal a significant increase in auditing research utilizing Chinese data, prominently featured in top-tier academic journals. This study categorizes six central themes, highlighting the broad range of topics explored using Chinese audit data. More importantly, the research identifies substantial cultural and contextual differences between China and Western nations, particularly the USA, that influence the auditing profession and markets. Exploring these themes underscores the invaluable insights derived from Chinese data, shedding light on areas not previously addressed by studies relying solely on Western datasets.Originality/valueThe value of this study lies in its comprehensive examination of seminal auditing studies using Chinese data, making a distinctive contribution to the auditing literature. This paper highlights the inadequacies of Western datasets in addressing certain auditing questions and emphasizes the unique advantages offered by China’s extensive public audit data, institutional characteristics and cultural determinants. The identified gap in the literature underscores the unexplored opportunities for further research in the Chinese auditing context. This study, therefore, provides a roadmap for future scholars, encouraging the exploration of new avenues and fostering a deeper understanding of the cultural nuances influencing auditing practices in China.
Drivers and outcomes of chatbot use in the business-to-business context: exploring business customers’ perspectives
Authors: Maga Sara , Bodlaj Mateja 
Published: December 2024

Purpose
Although chatbots are increasingly popular in the B2C literature, understanding of their use in a B2B perspective remains limited. The present study utilizes Uses and Gratification theory to explore what motivates business customers to use chatbots and how this use can affect professional relationships. This study aims to explore what motivates business customers to use chatbots and how this use can affect professional relationships. By utilizing Uses and gratifications theory, it seeks to deepen the currently limited understanding of the B2B perspective.

Design/methodology/approach
The study adopts an exploratory qualitative inquiry in the form of in-depth interviews with experts and business customers who had actual experience of using bots on their customer journey.

Findings
The study offers a much-needed examination of B2B customers’ perspectives about chatbots and proposes a model of the drivers and outcomes of chatbot use on the customer journey. Utilitarian and social motives are suggested to drive business customers to use chatbots, while the need to examine specific contingency factors to help determine a preference for chatbots is emphasized. Chatbots are shown to generate customer satisfaction with the firm and commitment to it, which adds to professional relationships.

Practical implications
Organizations relying on chatbots for customer interaction in B2B can use these results to build and maintain successful bots able to satisfy their customers’ needs and further contribute to building professional relationships.

Originality/value
The study identifies motives that explain why chatbots appeal to business customers, along with contingency factors that may further help distinguish their preference for technology vs. human interaction. It also suggests that chatbots can assist in building relationships between business customers and a selling firm.
Enterprise risk management effects on information systems-enabled strategic enterprise management: amplifying firm performance through strategic momentum and strategic flexibility in BRICS economies
Authors: Yoshikuni Adilson Carlos , Dwivedi Rajeev , Parisi Claudio , Oyadomari Jose Carlos Tiomatsu , Dultra-de-Lima Ronaldo Gomes 
Published: December 2024

PurposeEnterprise Risk Management (ERM) is a strategy and approach that enables organizations to manage risk strategically from a systems standpoint. The ERM assists businesses in structuring their systems to generate strategic flexibility (SF), which leads to increased firm performance (FP) through strategic enterprise management (IS-SEM) and strategic momentum (SM).Design/methodology/approachThe study is based on data gathered in Brazil and India. The complex link was discovered using partial least square structural equation modeling (PLS-SEM) using 330 Brazilian and Indian sample sizes.FindingsThe findings show that ERM influences IS-SEM and SM, which improves SF and FP. Furthermore, the study claims that IS-SEM can help improve strategic momentum and flexibility in the face of environmental uncertainty (ENU). Thus, it indicated that specific combinations of ENU connected with ERM and IS-SEM lead to obtaining high and extremely high levels fuzzy set qualitative comparative analysis (fsQCA) post hoc analysis of strategic momentum and flexibility.Practical implicationsThe findings help executives understand how ERM and accounting information systems (AIS) can help achieve SM and SF, hence promoting FP in situation specific ENU setups in developing economies. The findings enhance executives' comprehension of how ERM and IS-SEM can significantly contribute to achieving SM and SF, thereby driving FP in the situation-specific ENU configurations in developing economies. Originality/valueResearch indicated that specific combinations of (ENU) connected with ERM and IS-SEM lead to obtaining high and extremely high levels fuzzy set qualitative comparative analysis (fsQCA) post hoc analysis of strategic momentum and flexibility.
Triangulation and Delphi method analysis of alternative management scheme for sustainable public-rented flats
Authors: Arumsari Putri , Alisjahbana Sofia M. , Rarasati Ayomi Dita , Najid Najid 
Published: December 2024

Purpose
Currently, public-rented flats in Jakarta Province are managed by the Management Unit of Public-Rented Flats (MUPRF), which uses the Regional Revenue and Expenditure Budget (RREB) as the source of its financing. However, several previous studies have suggested that the MUPRF change its institutional scheme, to be more independent and not rely on the RREB as its source of finance. The study aims to identify three variable groups, public-rented flats’ characteristics, alternative institutional and financial schemes and challenges in the change of institutional and financial schemes.

Design/methodology/approach
This is a qualitative research, where both triangulation and the Delphi method are used to enrich findings. Triangulation is used to collect data from more than one source, and the Delphi method is used to gather opinions from experts and reach a consensus on the variables identified in the triangulation process.

Findings
Based on the findings there are 11 variables of public-rented flats’ characteristics, three variables of alternative institutional and financial schemes and four variables of challenges in the change of institutional and financial scheme.

Research limitations/implications
Through the triangulation process, only two sources were used, sources from previous research and regulations. In the Delphi method process, experts were staff from the Department of Community Housing and Settlement of the DKI Jakarta Province.

Originality/value
This research will be used as the basis on developing a system dynamics on how the MUPRF works as a system to figure out whether it can be changed into the alternative scheme proposed, with all the characteristics and challenges identified.
Technology-enabled engagement process of brand virtual-try-on services
Authors: Nawaz Muhammad Zahid , Guzmán Francisco , Nawaz Shahid 
Published: December 2024

Purpose
New-age technologies are driving brand digitalization and influencing consumer retail experiences and consumption patterns. Although past research addresses users’/consumers’ acceptance of these technologies in retail, it refrains from thoroughly studying interaction and engagement. Stemming from the technology acceptance model, the purpose of this paper is to empirically study the practicality of the technology-enabled engagement process comprising stages of interaction, psychological engagement, value-in-use and behavioral engagement during consumers’ interactions with augmented reality, artificial intelligence and machine learning based virtual try-on services.

Design/methodology/approach
Data from an online survey conducted in China of 339 consumers who experienced the virtual-try-on service is analyzed using partial least squares-structural equation modeling.

Findings
The results support the technology-enabled engagement process of brand virtual try-on services. Perceived ease of use and usefulness are robust antecedents of the framework during the interaction stage. Emotional and cognitive aspects contribute to the psychological engagement and value-in-use stages that convert into positive e-word of mouth and buying intentions about the brand in the behavioral engagement stage.

Originality/value
The research contributes to the technology acceptance model, information systems and technology marketing literature by testing a novel technology-enabled engagement process, which previously lacked empirical validation. Specifically, it uses technology acceptance model constructs as antecedents of the technology-enabled engagement process framework, with behavioral intentions in the form of e-word of mouth and buying intentions as precedents. It also provides insights into brands’ virtual try-on services in online retail environments. Practical implications for brand managers are discussed.