bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospektive 4-Jahres-Analyse geschlossener Drainagesysteme an einem dermatochirurgischen Zentrum – Notwendigkeit einer individualisierten Anwendung
Authors: Simgen J. , Gräber S. , Vogt T. , Müller C. S. L. 
Published: August 2019

Zusammenfassung
Hintergrund Aktuell sind die Indikationen zum Einsatz von Wund-Drainagen und die dabei eingesetzten Systeme in der Dermatochirurgie nicht klar definiert. Es existieren bislang keine publizierten Daten über die Verwendung von Drainagesystemen in der Dermatochirurgie.
Fragestellung Ziel der vorliegenden retrospektiven Studie war die Deskription des Patientenkollektivs, welches mit Wunddrainagen versorgt wurde, die Ableitung von Indikationen und assoziierten Komplikationen im Zusammenhang mit Wunddrainagen.
Methode Es wurden 495 Patienten in die Studie eingeschlossen, welche im Rahmen eines dermatochirurgischen Eingriffs im Zeitraum zwischen 2010 und 2014 mit Hoch- oder Niedervakuum-Drainage-Systemen therapiert wurden.
Ergebnisse Am häufigsten wurden Eingriffe am Lymphgefäßsystem beobachtet (n = 321; 64,8 %), v. a. Sentinel-Lymphknotenbiopsien wurden mit einer Drainage versorgt. Insgesamt kam es in 11,5 % der 495 Fälle (n = 57) zu postoperativen Komplikationen. Patienten mit Drainage-Versorgung unterschieden sich signifikant im Body Mass Index (p = 0,022), in operativer Defektgröße (p < 0,001) und Operationszeit (p < 0,001) von solchen ohne. Die Komplikationsraten bei Operationen mit Drainage unterschieden sich nicht signifikant (p = 0,118) von Operationen ohne Drainagen.
Schlussfolgerungen Mit dieser retrospektiven Analyse beschreiben wir die dermatochirurgischen Situationen, in denen Wunddrainagen verwendet wurden und vergleichen diese sowie assoziierte Komplikationen zwischen Eingriffen mit und ohne Wunddrainage. Wir favorisieren eine individualisierte Indikationsstellung unter Berücksichtigung patientenseitiger Faktoren anstelle fixer Regularien.
Stille Wasser
Authors: Textor Reinhard 
Published: August 2019

SummaryDie Psyche verschiebt unerwünschte oder angstbesetzte gedankliche oder emotionale Inhalte ins Unbewusste, wobei auch diese Verdrängung unbewusst geschieht. In den ersten beiden Lebensjahren vollziehen sich alle Entwicklungsschritte unbewusst, bis sich schließlich ein Selbst-Bewusstsein entwickelt und somit auch Neurosen entstehen können. Im Fallbeispiel äußerte sich ein unbewusster innerer Konflikt in scheinbar unerklärlichen Aggressionsausbrüchen - die nach dem Aufspüren der Ursache und lebenspraktischen Selbstbehauptungsübungen verschwanden.
Leser-Trélat-Syndrom assoziiert mit malignem Melanom
Authors: Troyanova-Slavkova S. , Kutzner H. , Kowalzick L. 
Published: August 2019

ZusammenfassungDas Leser-Trélat-Syndrom ist ein sehr seltenes paraneoplastisches Syndrom, gekennzeichnet durch akut exanthematisch auftretende, zahllose Verrucae seborrhoicae mit intensivem Pruritus auf nicht entzündlich veränderter Haut. Hier berichten wir über den Fall eines 68-jährigen Patienten, der aufgrund plötzlich aufgetretener, zahlreicher, juckender, dunkler seborrhoischer Keratosen bei uns vorstellig war. Während der klinischen Untersuchung fiel bei dem Patienten ein dunkel pigmentierter Naevus am linken Oberarm auf, der im Verlauf histologisch als malignes Melanom gesichert wurde. Die Pathogenese des Leser-Trélat-Syndroms ist noch nicht vollständig geklärt, das Auftreten dieses Syndroms wird v. a. bei Adenokarzinomen des Gastrointestinaltraktes, seltener bei Lymphomen und Leukämien beobachtet. Bis jetzt sind in der Literatur insgesamt 4 Fälle beschrieben, die eine Assoziation mit malignem Melanom darstellen.
„Das Beste aber ist das Wasser“
Authors: Bierbach Elvira 
Published: August 2019

SummaryDer Mensch besteht zu einem hohen Anteil aus Wasser. Dehydratation und Exsikkose führen zu gravierenden Einschränkungen der Körperfunktionen und unbehandelt zum Tod. Abgesehen von den etwa 125 l Trinkwasser zum Trinken, Kochen, Waschen etc. verbraucht jeder Westeuropäer täglich rund 3900 l virtuelles Wasser für Konsumgüter. Therapeutisch wird Wasser vielseitig eingesetzt – von Wickeln, Güssen und Bädern über Wassergymnastik bis hin zu Trinkkuren mit Heilwasser.
Automated classification of gastric neoplasms in endoscopic images using a convolutional neural network
Authors: Cho Bum-Joo , Bang Chang Seok , Park Se Woo , Yang Young Joo , Seo Seung In , Lim Hyun , Shin Woon Geon , Hong Ji Taek , Yoo Yong Tak , Hong Seok Hwan , Choi Jae Ho , Lee Jae Jun , Baik Gwang Ho 
Published: August 2019

Abstract
Background Visual inspection, lesion detection, and differentiation between malignant and benign features are key aspects of an endoscopist’s role. The use of machine learning for the recognition and differentiation of images has been increasingly adopted in clinical practice. This study aimed to establish convolutional neural network (CNN) models to automatically classify gastric neoplasms based on endoscopic images.
Methods Endoscopic white-light images of pathologically confirmed gastric lesions were collected and classified into five categories: advanced gastric cancer, early gastric cancer, high grade dysplasia, low grade dysplasia, and non-neoplasm. Three pretrained CNN models were fine-tuned using a training dataset. The classifying performance of the models was evaluated using a test dataset and a prospective validation dataset.
Results A total of 5017 images were collected from 1269 patients, among which 812 images from 212 patients were used as the test dataset. An additional 200 images from 200 patients were collected and used for prospective validation. For the five-category classification, the weighted average accuracy of the Inception-Resnet-v2 model reached 84.6 %. The mean area under the curve (AUC) of the model for differentiating gastric cancer and neoplasm was 0.877 and 0.927, respectively. In prospective validation, the Inception-Resnet-v2 model showed lower performance compared with the endoscopist with the best performance (five-category accuracy 76.4 % vs. 87.6 %; cancer 76.0 % vs. 97.5 %; neoplasm 73.5 % vs. 96.5 %; P  < 0.001). However, there was no statistical difference between the Inception-Resnet-v2 model and the endoscopist with the worst performance in the differentiation of gastric cancer (accuracy 76.0 % vs. 82.0 %) and neoplasm (AUC 0.776 vs. 0.865).
Conclusion The evaluated deep-learning models have the potential for clinical application in classifying gastric cancer or neoplasm on endoscopic white-light images.
venenkleber.koeln – Erfahrungen und Ergebnisse nach 1015 Stammvenenbehandlungen – Die bessere Alternative zur Stripping Operation?
Authors: Fuchs J. 
Published: August 2019

ZusammenfassungEndovenöse Methoden in der Behandlung inkompetenter Venen haben sich in Deutschland etabliert. Obwohl sie eine effektive Alternative zur chirurgischen Therapie darstellen, handelt es sich unverständlicherweise nicht um Eingriffe der ersten Wahl. Ganz im Gegensatz zu internationalen Empfehlungen. Risiken und Nebenwirkungen lassen sich durch die nicht-thermischen Verfahren weiter reduzieren. Ist die Varizen-Verklebung mit Cyanoacrylat eine weitere Verbesserung? Nach 1015 Prozeduren mit dem Venenkleber an inkompetenten Stammvenen werden die eigenen Ergebnisse vorgestellt und diskutiert.
Workplace Exposures
Authors: Lee Janet T. , Gaertner Wolfgang B. 
Published: August 2019

AbstractWorkplace exposure in colorectal surgery is unique compared with other surgical specialties and generally underreported. Although the most common device-associated exposure in surgery is suture needle injury, colorectal surgeons are increasingly exposed to gastrointestinal-related infectious agents, radiation, and other hazards in multiple different clinical settings. Highlighting the unique workplace exposures in colorectal surgery may help increase awareness, improve education, and identify possible targets for early intervention in order to minimize these risks.
Transition to Surgical Practice: The Early Years
Authors: Paquette Ian M. 
Published: August 2019

AbstractThe transition from years of surgical training to independent surgical practice is a time to enjoy the well-earned achievement of completion of training. The early years of clinical practice bring about many challenges to the young surgeon. These include transitioning to a more independent role in the operating room, running an office and understanding the business aspects of medicine, building clinical networks to sustain a clinical practice, and building a professional and academic reputation. This article will discuss aspects that are unique to the early career surgeon. Where possible, I will use the available literature to augment the discussion, whereas, in other areas, I will offer my thoughts from personal experience on the topic.
Simulation Of Coffee Stain Effects Using ANSYS Fluent
Authors: Singh Amardeep 
Published: August 2019

AbstractThe following project takes an investigative look in the commonly observed coffee stain effect in fluid dynamics that explains the arrangement and alignment of particles and droplets when subjected to an evaporative flux. The primary objective of the paper deals with the methodology and results obtained by the simulation of the effect in ANSYS fluent and the parameters used to produce the effect. The latter part of the project studies the relation between surface energies and contact angles for droplets and seeks to develop a relationship between both. The coffee stain effect has been further replicated using Surface Evolver, Energy 2D and the FEA Multiphysics Toolbox from MATLAB. Coffee stain simulations are a greater way of interpreting a widely known phenomenon that have captivated the interests of researchers and the following report intends to understand such dynamics and replicate them in software environments.
Development of Daptomycin Susceptibility Breakpoints for Enterococcus faecium and Revision of the Breakpoints for Other Enterococcal Species by the Clinical and Laboratory Standards Institute
Authors: Satlin Michael J , Nicolau David P , Humphries Romney M , Kuti Joseph L , Campeau Shelley A , Lewis II James S , Weinstein Melvin P , Jorgensen James H 
Published: August 2019

Abstract
Daptomycin is one of the few treatment options for infections caused by enterococci that are resistant to ampicillin and vancomycin, such as vancomycin-resistant Enterococcus faecium. The emergence and clinical significance of daptomycin-resistant enterococci and evolving microbiologic, pharmacokinetic-pharmacodynamic, and clinical data indicated that the pre-2019 Clinical and Laboratory Standards Institute (CLSI) susceptible-only breakpoint of ≤4 μg/mL for daptomycin and enterococci was no longer appropriate. After analyzing data that are outlined in this article, the CLSI Subcommittee on Antimicrobial Susceptibility Testing established new breakpoints for daptomycin and enterococci. For E. faecium, a susceptible dose-dependent (SDD) breakpoint of ≤4 μg/mL was established based on an increased dosage of 8–12 mg/kg/day (≥8 μg/mL-resistant). CLSI suggests infectious diseases consultation to guide daptomycin use for the SDD category. For Enterococcus faecalis and other enterococcal species, revised breakpoints of ≤2 μg/mL-susceptible, 4 μg/mL-intermediate, and ≥8 μg/mL-resistant were established based on a standard dosage of 6 mg/kg/day.
Development and prognostic validation of partition values to grade right ventricular dysfunction severity using 3D echocardiography
Authors: Muraru Denisa , Badano Luigi P , Nagata Yasufumi , Surkova Elena , Nabeshima Yosuke , Genovese Davide , Otsuji Yutaka , Guida Valentina , Azzolina Danila , Palermo Chiara , Takeuchi Masaaki 
Published: August 2019

Abstract

Aims
Transthoracic 3D echocardiography (3DE) has been shown to be feasible and accurate to measure right ventricular (RV) ejection fraction (EF) when compared with cardiac magnetic resonance (CMR). However, RV EF, either measured with CMR or 3DE, has always been reported as normal (RV EF &gt; 45%) or abnormal (RV EF ≤ 45%). We therefore sought to identify the partition values of RV EF to stratify RV dysfunction in mildly, moderately, or severely reduced as we are used to do with the left ventricle.

Methods and results
We used 3DE to measure RV EF in 412 consecutive patients (55 ± 18 years, 65% men) with various cardiac conditions who were followed for 3.7 ± 1.4 years to obtain the partition values which defined mild, moderate, and severe reduction of RV EF (derivation cohort). Then, the prognostic value of these partition values was tested in an independent population of 446 patients (67 ± 14 years, 58% men) (validation cohort). During follow-up, we recorded 59 cardiac deaths (14%) in the derivation cohort. Using K-Adaptive partitioning for survival data algorithm we identified four groups of patients with significantly different mortality according to RV EF: very low &gt; 46%, 40.9% &lt; low ≤ 46%, 32.1% &lt; moderate ≤ 40.9%, and high ≤ 32.1%. To make the partition values easier to remember, we approximated them to 45%, 40%, and 30%. During 4.1 ± 1.2 year follow-up, 38 cardiac deaths and 88 major adverse cardiac events (MACE) (cardiac death, non-fatal myocardial infarction, ventricular fibrillation, or admission for heart failure) occurred in the validation cohort. The partition values of RV EF identified in the derivation cohort were able to stratify both the risk of cardiac death (log-rank = 100.1; P &lt; 0.0001) and MACEs (log-rank = 117.6; P &lt; 0.0001) in the validation cohort too.

Conclusion
Our study confirms the independent prognostic value of RV EF in patients with heart diseases, and identifies the partition values of RV EF to stratify the risk of cardiac death and MACE.
Cardiac mucormycosis: a case report
Authors: Krishnappa Darshan , Naganur Sanjeev , Palanisamy Dinesh , Kasinadhuni Ganesh 
Published: August 2019

Abstract

Background
Mucormycosis is an invasive fungal infection (IFI) most commonly seen in immunocompromised patients. Diabetic ketoacidosis, haematopoietic transplantation, iron overload states, and deferoxamine therapy are considered to be some of the classical risk factors. While cutaneous and rhino-sinusoidal forms may be seen in immunocompetent (IC) individuals, cardiac and mediastinal involvement is rare. In this report, we describe a young patient without predisposing factors who presented as mediastinal mucormycosis with extensive cardiac involvement.

Case summary
A 19-year-old male presented with complaints of dry cough and dyspnoea on exertion over the last 4 months. Echocardiography showed diffuse infiltration of both atria along with multiple pedunculated freely mobile masses. A computed tomography chest was done to further delineate the true extent of the disease and revealed diffuse infiltration of the mediastinum, bilateral atria and interatrial septum, pulmonary veins, and superior vena cava. A fine needle aspiration cytology from a mediastinal mass revealed broad aseptate fungal hyphae with right angled branching consistent with Mucor. Extensive evaluation could not find any predisposing factors. The patient was started on Amphotericin B and surgical debridement was contemplated. However, owing to the diffuse infiltration around the heart and mediastinal vasculature, debridement could not be performed and the patient eventually succumbed to the illness.

Discussion
Mediastinal mucormycosis though rare in IC patients, is a rapidly progressive condition with a high fatality. A high index of suspicion needs to be maintained in individuals presenting with infiltrative disorders of the mediastinum for early diagnosis and prompt treatment.
The Quiet Expansion of Universal Jurisdiction
Authors: Langer Máximo , Eason Mackenzie 
Published: August 2019

Abstract
Based on an original worldwide survey of all universal jurisdiction complaints over core international crimes presented between 1961 and 2017 and against widespread perception by international criminal law experts that universal jurisdiction is in decline, this article shows that universal jurisdiction practice has been quietly expanding as there has been a significant growth in the number of universal jurisdiction trials, in the frequency with which these trials take place year by year and in the geographical scope of universal jurisdiction litigation. This expansion is likely the result of, among other factors, the adoption of International Criminal Court implementing statutes, the creation of specialized international crimes units by states, institutional learning by states and non-governmental organizations (NGOs), technological changes, new migration and refugee waves to universal jurisdiction states, criticisms of international criminal law as neo-colonial and the search of new venues by human rights NGOs. The expansion of universal jurisdiction has been quiet because most tried defendants have been low-level, universal jurisdiction states have not made an effort to publicize these trials and observers have wrongly assumed that Belgium and Spain were representative of universal jurisdiction trends. The article finally assesses positive and negative aspects of the quiet expansion of universal jurisdiction for its defenders and critics.
Precision nomenclature for the new genomics
Authors: Lewin Harris A , Graves Jennifer A Marshall , Ryder Oliver A , Graphodatsky Alexander S , O'Brien Stephen J 
Published: August 2019

Abstract
The confluence of two scientific disciplines may lead to nomenclature conflicts that require new terms while respecting historical definitions. This is the situation with the current state of cytology and genomics, which offer examples of distinct nomenclature and vocabularies that require reconciliation. In this article, we propose the new terms C-scaffold (for chromosome-scale assemblies of sequenced DNA fragments, commonly named scaffolds) and scaffotype (the resulting collection of C-scaffolds that represent an organism's genome). This nomenclature avoids conflict with the historical definitions of the terms chromosome (a microscopic body made of DNA and protein) and karyotype (the collection of images of all chromosomes of an organism or species). As large-scale sequencing projects progress, adoption of this nomenclature will assist end users to properly classify genome assemblies, thus facilitating genomic analysis.
Wildlife Habitat Management and Changing Forest Practices in the Northeast
Authors: Crawford Hewlette S. 
Published: August 2019

Abstract
Increasingly intensive management of northeastern industrial forestlands will substantially affect wildlife habitat. Opportunities for increasing wildlife habitat values on the best forest sites may be impractical because high timber management costs preclude loss of wood products to favor wildlife. Wildlife habitat can be enhanced on low-quality timber sites, but inherent site productivity will limit gains. The most practical opportunity for increasing wildlife habitat values usually is on intermediate-quality sites. Increased habitat value can be accomplished by coordinating timber and wildlife-habitat management goals. Gains in wildlife habitat value must be quantified to help offset losses in timber values. Citation: Northern Journal of Applied Forestry, April 1984. NJ 1:12-14.
Inventory Design and the Ten-Plots-per-Stand Syndrome
Authors: Ek Alan R. , Rose Dietmar W. , Gregersen Hans M. 
Published: August 2019

Abstract
Common Lake States practices of stand description and inventory, and continuous forest inventory (CFI) are criticized. The origin of current practices is discussed and suggestions are made for refinement of practices in light of emerging forest sampling and managment decision-making techniques. Emphasis is placed on developing data of varying precision levels that meet the requirements for specific forest managment and planning problems. North. J. Appl. For. 1:76-79, Dec. 1984.
Willingness of Michigan Landowners to Sell Fuelwood
Authors: Parker Richard G. 
Published: August 2019

Abstract
Foresters who work with private landowners are involved almost daily with buying, selling, processing, and marketing fuelwood. In a Michigan case study, approximately 20% of the landowners questioned holding over 35% of the forest land said they would sell fuelwood immediately at the market price. Another 25% would sell now, but only at a higher price, whereas 20% were willing to sell but later, generally to meet economic goals. More than 30% said they would never sell fuelwood, but, given the opportunity, evidence suggests some would sell. Owners of small holdings and absentee owners were less willing to sell. Timber stand improvement and wildlife habitat improvement proved strong nonprice incentives. This information should be useful in assessing timber supplies and in designing efforts to interest landowners in improved forest practice. North, J. Appl. For. 1:85-87, Dec. 1984.
Variation in Diameter Growth of Red Maple Progenies Grown in Ohio, Michigan, and Minnesota
Authors: Townsend Alden M. , Bentz Susan E. , Douglass Larry W. 
Published: August 2019

Abstract
Significant variation in diameter (dbh) growth was found among 19-yr-old red maple progenies grown in Ohio, Michigan, and Minnesota, from seed collected in 50 provenances scattered throughout the species' range. Both the provenance of origin, and one-parent families within provenances, were significant sources of variation in all three plantations. The fastest growing trees in Ohio and Michigan generally were from north central or east central portions of the range, whereas the largest trees in the Minnesota plantation were from northern Maine, northern Michigan, northern Ontario, and northern Wisconsin. Trees from southern seedlots grew most slowly in all plantings. Average diameter growth rate of seedlings from the same provenance was most often similar in Ohio and Michigan; less consistency was found between Ohio and Minnesota and between Michigan and Minnesota. Provenances from near Bethel, Maine; Houghton, Michigan; Rhinelander, Wisconsin; and Chalk River, Ontario yielded trees which showed above-average growth in all three plantations. North. J. Appl. For. 10(1): 28-31.
Comparison of the Centroid Method and Taper Systems for Estimating Tree Volumes
Authors: Patterson David W. , Wiant Harry V. , Wood Geoffrey B. 
Published: August 2019

Abstract
There is a need to be able to accurately determine the volumes of trees. Current methods include the use of volume tables or taper systems which should be tested for applicability before use in a given stand. This can be costly and time consuming. The objective of this study was tocompare the estimates made using accepted taper systems and the more "generic" centroid method and determine which gives the best results. Twenty trees each of northern red oak and red pine and 19 yellow-poplar trees were harvested. Diameter measurements were taken every 4 in. with calipersfor the first 40 ft of each stem. These measurements were used to calculate the "true" or control volumes. The appropriate taper system for each species and the centroid method were used to estimate the tree volumes, and these estimates were compared with the control volumes. The centroidmethod was less biased than taper systems for all three species. Precision was better for the centroid method than taper systems for yellow-poplar and red pine, but not for northern red oak. North. J. Appl. For. 10(1): 8-9.