bluuebunny/crossref_metadata_2025_split huggingface dataset:
On Analytical Extension of Generalized Hypergeometric Function 3F2
Authors: Dmytryshyn Roman , Oleksyn Volodymyra 
Published: November 2024

The paper considers the generalized hypergeometric function F23, which is important in various fields of mathematics, physics, and economics. The method is used, according to which the domains of the analytical continuation of the special functions are the domains of convergence of their expansions into a special family of functions, namely branched continued fractions. These expansions have wide domains of convergence and better computational properties, particularly compared with series, making them effective tools for representing special functions. New domains of the analytical continuation of the generalized hypergeometric function F23 with real and complex parameters have been established. The paper also includes examples of the presentation and extension of some special functions.
A New Heterometallic Silver/Cadmium Thiocyanate Directed by Benzyl Viologen Possessing Photocurrent Response and Photocatalytic Degradation on Rhodamine B in Artificial Seawater
Authors: Zhuang Xueqiang , Huang Xihe , Li Haohong , Lin Tianjin , Gao Yali 
Published: November 2024

The search for new heterometallic metal pseudohalides will be significant for the development of novel functional materials. In this work, a new silver/cadmium heterometallic thiocyanate templated by benzyl viologen has been synthesized and structurally determined, i.e., {(BV)[Ag2Cd(SCN)6]}n (BV2+ = benzyl viologen). The interesting 1-D double chain [Ag2Cd(SCN)6]n2n− was constructed from the CdN6 octahedron and Ag2SCN6 dimers via μ2-SCN and μ3-S,S N SCN bridge, in which the Ag···Ag interaction can be found. Inter-molecular C-H···S/N hydrogen bonds between BV2+ cations and [Ag2Cd(SCN)6]n2n− chains contribute to the formation of a stable 3-D network. The short S···N distance implies the strong charge transfer (CT) interactions between the electron-rich silver/cadmium thiocyanate donor and BV2+ acceptor. This hybrid can exhibit a photo-generated current performance with an intensity of 1.75 × 10−8 A. Interestingly, this hybrid can present good photocatalytic degradation performance on rhodamine B in artificial seawater with a degradation ratio of 86.5% in 240 min. This work provides a new catalyst way for the organic dye-type ocean pollutant treatments.
Follow the Path: Unveiling an Azole Resistant Candida parapsilosis Outbreak by FTIR Spectroscopy and STR Analysis
Authors: De Carolis Elena , Magrì Carlotta , Camarlinghi Giulio , Ivagnes Vittorio , Spruijtenburg Bram , Meijer Eelco F. J. , Scarselli Cristiano , Parisio Eva Maria , Sanguinetti Maurizio 
Published: November 2024

Accurate identification and rapid genotyping of Candida parapsilosis, a significant opportunistic pathogen in healthcare settings, is crucial for managing outbreaks, timely intervention, and effective infection control measures. This study includes 24 clinical samples and 2 positive environmental surveillance swabs collected during a fluconazole-resistant Candida parapsilosis outbreak at the Tuscany Rehabilitation Clinic (Clinica di Riabilitazione Toscana, CRT), located in the province of Arezzo, Italy. Fourier-transform infrared (FTIR) spectroscopy, genetic sequencing of the ERG11 gene, and short tandem repeat (STR) analysis was applied to track the fluconazole-resistant C. parapsilosis outbreak at the CRT facility. FTIR analysis clustered the isolates into two major groups, correlating with resistance-associated ERG11 mutations (Y132F and R398I), azole resistance levels, and year of isolation. The combined use of FTIR spectroscopy and STR typing provided a comprehensive approach to identify and track fluconazole-resistant C. parapsilosis isolates, which identified specific clusters of genetically similar isolates. By comparison with feasible molecular techniques, we conclude that FTIR spectroscopy applied in real time can inform targeted infection control strategies and aid in the effective management of nosocomial infections.
Metagenomic Analysis of Sediment Bacterial Diversity and Composition in Natural Lakes and Artificial Waterpoints of Tabuk Region in King Salman Bin Abdulaziz Royal Natural Reserve, Saudi Arabia
Authors: Al-Awthan Yahya S. , Mir Rashid , Alharbi Basmah M. , Alatawi Abdulaziz S. , Almutairi Fahad M. , Khafaga Tamer , Shohdi Wael M. , Fakhry Amal M. , Alatawi Mashari M. 
Published: November 2024

The Tabuk region is located in the northern part of Saudi Arabia, and it has an area of 117,000 km2 between longitudes 26° N and 29° N and latitudes 34° E and 38° E. King Salman Bin Abdulaziz Royal Natural Reserve (KSRNR) is the largest natural reserve in Saudi Arabia and covers about 130,700 km2. It represents a new tourist attraction area in the Tabuk region. Human activities around the lake may lead to changes in water quality, with subsequent changes in microenvironment components, including microbial diversity. The current study was designed to assess possible changes in bacterial communities of the water sediment at some natural lakes and artificial waterpoints of KSRNR. Water samples were collected from ten different locations within KSRNR: W1, W2, W3 (at the border of the royal reserve); W4, W5, W6, W7 (at the middle); and W8, W9, and W10 (artificial waterpoints). The total DNA of the samples was extracted and subjected to 16S rRNA sequencing and metagenomic analysis; also, the environmental parameters (temperature and humidity) were recorded for all locations. Metagenomic sequencing yielded a total of 24,696 operational taxonomic units (OTUs), which were subsequently annotated to 193 phyla, 215 classes, 445 orders, 947 families, and 3960 genera. At the phylum level, Pseudomonadota dominated the microbial communities across all samples. At the class level, Gammaproteobacteria, Clostridia, Alphaproteobacteria, Bacilli, and Betaproteobacteria were the most prevalent. The dominant families included Enterobacteriaceae, Pseudomonadaceae, Clostridiaceae, Comamonadaceae, and Moraxellaceae. At the genus level, Pseudomonas, Clostridium, Acinetobacter, Paenibacillus, and Acidovorax exhibited the highest relative abundances. The most abundant species were Hungatella xylanolytica, Pseudescherichia vulneris, Pseudorhizobium tarimense, Paenibacillus sp. Yn15, and Enterobacter sp. Sa187. The observed species richness revealed substantial heterogeneity across samples using species richness estimators, Chao1 and ACE, indicating particularly high diversity in samples W3, W5, and W6. Current study results help in recognizing the structure of bacterial communities at the Tubaiq area in relation to their surroundings for planning for environmental protection and future restoration of affected ecosystems. The findings highlight the dominance of various bacterial phyla, classes, families, and genera, with remarkable species richness in some areas. These results underscore the influence of human activities on microbial diversity, as well as the significance of monitoring and conserving the reserve’s natural ecosystems.
Alteration in the Gut Microbiota of Chickens Resistant to Eimeria tenella Infection
Authors: Qiao Yu , Feng Qian , Wang Qingjie , Zhao Qiping , Zhu Shunhai , Zhao Fanghe , Wang Zhongchuang , Zhang Ruiting , Wang Jinwen , Yu Yu , Han Hongyu , Dong Hui 
Published: November 2024

Avian coccidiosis, caused by several species of Eimeria, is a widespread and economically important poultry disease that inflicts severe losses in the poultry industry. Understanding the interplay between Eimeria and gut microbiota is critical for controlling coccidiosis and developing innovative treatments to ensure good poultry health. In the present study, chickens were immunized six times with a low dose of Eimeria tenella, resulting in complete immunity against Eimeria infection. The results of fecal microbiota transplantation showed that the gut microbiota of immunized chickens induced a certain degree of resistance to coccidial infection. To investigate the types of intestinal microbiota involved in the development of resistance to Eimeria, the intestinal contents and fecal samples from both immunized and unimmunized groups were collected for 16S rRNA gene sequencing. The results showed that, at the genus level, the abundance of the Eubacterium coprostanoligenes group, Erysipelatoclostridium, Shuttleworthia, and Colidextribacter was significantly increased in the intestinal content of immunized chickens, whereas the abundance of Eisenbergiella was significantly decreased. In fecal samples, the abundance of Clostridiaceae and Muribaculaceae significantly increased, whereas that of Bacillales significantly decreased. These findings will help to elucidate the interactions between E. tenella and the gut microbiota of chickens, providing a basis for isolating E. tenella-resistant strains from the gut microbiome and developing new vaccines against coccidiosis.
Identification of Target Gene and Interacting Protein of Two LaSCL6 Alternative Splicing Variants Provides Novel Insights into Larch Somatic Embryogenesis
Authors: Zang Qiao-Lu , Ye Zha-Long , Qi Li-Wang , Li Wan-Feng 
Published: November 2024

Somatic embryogenesis is valuable for clonal propagation and genetic improvement, and it also serves as an ideal system for studying plant development mechanisms. In Larix kaempferi, microRNA171 and its target gene L. kaempferi SCARECROW-LIKE6 (LaSCL6), which has two alternative splicing variants, can regulate somatic embryogenesis; however, the underlying molecular mechanism is still unknown. In this study, we overexpressed these two LaSCL6 variants in Oryza sativa and Arabidopsis thaliana and then used the RNA-Seq method to screen genes from O. sativa and A. thaliana, whose expression patterns are related to those of LaSCL6 variants. The screened genes were then used to search L. kaempferi proteins to identify the candidate target genes of LaSCL6. After yeast one-hybrid and dual- luciferase transcriptional activity assays, cytochrome P450, family 89, subfamily A, polypeptide 5 (CYP89A5), and wall-associated receptor kinase-like 20 (WAKL20) were confirmed to be the target genes of LaSCL6-var1; in addition, WAKL20 and UDP-glycosyltransferase 85A3 (UGT85A3) were confirmed to be the target genes of LaSCL6-var2. Moreover, APETALA2-like protein 2, a transcription factor from the AP2/ERF family, was shown to interact with LaSCL6-var1 and LaSCL6-var2. Taken together, our results suggest a regulatory network of miR171-LaSCL6. The findings presented here not only provide novel insights into the regulation of the miR171-LaSCL6 module but also explain the mechanism underlying larch somatic embryogenesis and other biological processes.
Results on Third-Order Differential Subordination for Analytic Functions Related to a New Integral Operator
Authors: Maktoof Sara Falih , Atshan Waggas Galib , Alkiffai Ameera N. 
Published: November 2024

In this paper, we aim to give some results for third-order differential subordination for analytic functions in the open unit disk U=z:z∈C and z<1 involving the new integral operator μα,nm(f∗g). The results are obtained by examining pertinent classes of acceptable functions. New findings on differential subordination have been obtained. Additionally, some specific cases are documented. This work investigates appropriate classes of admissible functions, presents a novel of new integral operator, and discusses the properties of third-order differential subordination. The properties and results of the differential subordination are symmetrical to the properties of the differential superordination to form the sandwich theorems.
Malaria Vectors and Plasmodium Transmission in Malaria-Endemic Localities of Colombia
Authors: Piedrahita Stefani , Correa Margarita M. 
Published: November 2024

Anopheles species composition, abundance, and Plasmodium natural infection are important aspects to assess malaria transmission risk. In this study, these aspects were evaluated in a large number of localities in the most important malaria-endemic regions of Colombia. Mosquitoes were collected from 2012 to 2015 in 55 localities of northwestern and western Colombia. Anopheles species composition, abundance, and Plasmodium infection were estimated. A total of 13,218 Anopheles specimens were evaluated. The highest species richness was detected in the northwest, where the main vectors, An. albimanus (27.8%) and An. nuneztovari (26.7%), were the most abundant species. In the west, An. nuneztovari predominated (51.6%), followed by An. darlingi (29.2%). Six species were infected with Plasmodium, An. darlingi, An. nuneztovari, An. albimanus, An. calderoni, An. triannulatus, and An. braziliensis. Results showed that in these localities the main Colombian vectors are widely spread, which suggests a high malaria risk. Notably, this study is the first to report An. braziliensis from Colombia as being naturally infected with Plasmodium. Infection results for species that are suspected local vectors indicate the importance of conducting further studies to assess their epidemiological importance. This information provides the basis for the application of directed vector control strategies that are species-specific.
Preloading Clearance Effects on Hydrodynamic Characteristics of Preloading Spiral Case and Concrete in Pump Mode
Authors: Zhang Shaozheng , Zhang Xiaopeng , Luo Yutong , Gao Tiankuo , Wang Zhengwei 
Published: November 2024

The spiral case plays a role in providing stable and uniform water flow in the pump-turbine unit, and the overall structure with the surrounding concrete is an important foundation for the safe and stable operation of the unit and power plant. In order to clarify the comprehensive bearing capacity of preloading steel spiral case under pump operating conditions, this study is based on the theory of the fluid–structure coupling and contact model and uses ANSYS CFX 2021 R1 and mechanical to analyze the flow fluctuation characteristics and dynamic structural response of a preloading steel spiral case and surrounding concrete under different preloading pressures in the intermediate head pump condition. The results indicate that the main frequency of pressure fluctuations inside the main frequency (1 fn) of pressure fluctuations inside the spiral case is influenced by the unstable flow. The contact state between the preloading steel spiral case and concrete is closely related to the relative magnitude of preloading pressure and hydraulic pressure. Higher preloading pressure can lead to an increase in initial preloading clearance, resulting in a decrease in contact area. The vortex motion inside the spiral case is the main factor affecting the distribution of deformation. The rotor–stator interaction also has a certain impact on the vibration of the spiral case structure, even though the influence of rotor–stator interaction on pressure fluctuation inside the spiral case is already small. The monitoring points where the maximum values of static stress and dynamic stress are located are different. Increasing the preloading pressure value does not always guarantee the safety of concrete structures, as the sticking contact area in early contact transfers most of the stress of the spiral case, resulting in significant stress concentration. Under the working conditions of this study, the concrete in contact with the inner edge and nose vane is subjected to excessive loads. Therefore, it is necessary to reinforce the structure with steel bars or other methods to improve its tensile strength. A minimum preloading pressure value of 3.2 MPa is beneficial for reducing the risk of concrete cracking. The research results can provide a deeper understanding of the behavior of preloading steel spiral cases under pump conditions and guide optimization design.
ИССЛЕДОВАНИЯ ТИПА «СЛУЧАЙ-КОНТРОЛЬ» В ЗДРАВООХРАНЕНИИ
Authors: А.М. Гржибовский , С.В. Иванов , М.А. Горбатова 
Published: October 2024

В настоящей работе представлены основные принципы планирования, проведения и статистической обработки данных исследований типа «случай-контроль» в здравоохранении. Приведены практические примеры расчета размера выборки и оценки связи между факторами риска с помощью онлайн-калькуляторов и пакета для обработки эпидемиологических данных Epi Info. Авторы представляют практические примеры использования исследований типа «случай-контроль» в литературе, а также достоинства и недостатки данного типа исследований. Настоящая статья призвана дать общие сведения об исследованиях типа «случай-контроль», и не заменяет прочтения специализированной литературы по клинической эпидемиологии.
In this paper we present basic principles of planning and carrying out case-control studies in health sciences as well as analyzing the data collected in these studies. We present practical examples of sample size and effect measures calculation for matched and unmatched case-control studies using online calculators and Epi Info software. Examples of studies using case-control design from international peer-reviewed literature are also presented. This article provides general introduction to case-control studies and does not substitute specialized literature in clinical epidemiology.
Осы жұмыста денсаулық сақтаудағы көлденең «жағдай-бақылау» жоспарлау, өткізу және статистикалық өңдеудің негізгі принциптері көрсетілген. Epi Info эпидемиологиялық мәліметтерді өңдеу үшін онлайн-калькуляторлар мен пакет көмегімен қауіп факторлары арасындағы байланысты таңдау және бағалау мөлшері есебінің практикалық мысалдары келтірілген. Авторлар әдебиеттегі көлденең «жағдай-бақылау» зерттеулерді пайдаланудың практикалық мысалдарын, сол сияқты осы зерттеу түрлері қасиеттері мен жетіспеушіліктерін келтіреді. Осы мақала көлденең «жағдай-бақылау»зерттеулер туралы жалпы мәліметтер беруге бейімделген, және клиникалық эпидемиология бойынша мамандандырылған әдебиетті оқуды ауыстырмайды.
ОСОБЕННОСТИ ЛЕЧЕНИЯ ХРОНИЧЕСКОГО ГЕПАТИТА С У ВИЧ-ИНФИЦИРОВАННЫХ БОЛЬНЫХ: ОБЗОР ЛИТЕРАТУРЫ
Authors: Н.Е. Сарсекеева , Б.Н. Кошерова 
Published: October 2024

Карагандинский государственный медицинский университет, г. Караганда, Казахстан Состояние иммунодефицита при ВИЧ-инфекции способствует прогрессированию вирусного гепатита. В настоящее время инфекция, вызванная вирусом гепатита С, широко распространена среди ВИЧ-инфицированных пациентов. В статье представлен обзор данных литературы об особенностях лечения хронического гепатита С у ВИЧ-инфицированных больных.
The immunodeficiency condition associated with HIV-infection is contributing to the progress of viral hepatitis. At present, an infection caused by the hepatitis C virus is common among HIV-infected patients. The article provides an overview of the literature about the features of the treatment of chronic hepatitis C in HIV-infected patients. Keywords: chronic hepatitis C, HIV infection, treatment.
АИВ-инфекциясымен астасқан иммун жетіспеушіліктің жағдайы вирустық гепатиттің ағымын тездетуге жәрдемдеседі. Қазіргі уақытта АИВ-инфекцияланған науқастар арасынан С вирусті гепатитті тудырған індет кеңінен тарап отыр. Мақалада АИВ-инфекцияланған науқастардағы созылмалы C гепатитінің емдеу ерекшеліктері туралы әдебиеттің тізімі берілген.
АРТЕРИАЛДЫ ГИПЕРТОНИЯ ДАМУЫНДА БІРҚАТАР ГЕНДЕР ПОЛИМОРФИЗМІНІҢ ОРНЫ
Authors: А.М. Марқабаева 
Published: October 2024

Семей қаласының Мемлекеттік медицина университеті, Семей қ, Қазақстан Әдебиеттік шолуда артериалды гипертония дамуындағы молекулалық – генетикалық механизмдерді зерттеу нәтижесі мен қан айналым жүйесі ауруларында гендер полиморфизмініңорны туралы жазылған. Ангиотензиноген, азот тотығы және эндотелин – 1 мысалға ала отырып артериалды қан қысымының молекулалық - генетикалық реттелуіне жаңаша көзқараспен қарау.
Semey State Medical University, Semey City, Kazakhstan The review presents results of the study of molecular and genetic mechanisms of hypertension. Also new look at the molecular and genetic regulation of blood pressure by the example of the angiotensinogen, nitric oxide and endothelin-1 genes polymorphisms.
Государственный медицинский университет города Семей, г. Семей, Казахстан В обзоре представлены результаты изучения молекулярно-генетических механизмов развития артериальной гипертензии и патофизиологическая роль полиморфизма генов при болезнях системы кровообращения. Представлен новый взгляд на молекулярно-генетическую регуляцию артериального давления на примере полиморфизма генов ангиотензиногена, оксида азота и эндотелина-1.
КОРРЕЛЯЦИОННЫЙ АНАЛИЗ ДАННЫХ С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS
Authors: А.М. Гржибовский , С.В. Иванов , М.А. Горбатова 
Published: November 2024

В настоящей работе представлены общие сведения о выполнении корреляционного анализа данных с использованием параметрических и непараметрических методов. Приведены алгоритмы расчета коэффициентов корреляции Пирсона, Спирмена и Кендалла с использованием программного обеспечения Statistica 10 и SPSS 20 и интерпретация полученных результатов анализа. Настоящая статья призвана дать общие сведения о корреляционном анализе,и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии.
In this paper we present the main principles of correlation analysis using parametric and non-parametric methods. Algorithms for calculations of Pearson’s, Spearmen’s and Kendall’s coefficients using Statistica 10 and SPSS 20 software are presented. Special emphasis is given to interpretation of results of statistical analysis. The article complements, but does not substitute specialized literature on biostatistics and clinical epidemiology.
Осы жұмыста параметрлік және параметрлік емес әдістерді қолданумен корреляциялық талдау мәліметтерін орындау туралы жалпы мәліметтер ұсынылды.Statistica 10 және SPSS 20 бағдарламалыққамсындандырудықолданумен Пирсонның, Спирменның және Кендаллдың корреляциялары коэфициенттерін есептеу алгоритмдері және алынған талдау нәтижелері интерпретациясы келтірілген. Осы мақала корреляциялық мәліметтерді талдау туралы жалпы мәліметтер беруге талап етілген және статистика және клиникалық эпидемиология бойынша мамандандырылған әдебиетті оқудың орнын толтырмайды.
ПРИМЕНЕНИЕ АНАЛИЗА ВЫЖИВАЕМОСТИ В ЗДРАВООХРАНЕНИИ С ИСПОЛЬЗОВАНИЕМ ПАКЕТА СТАТИСТИЧЕСКИХ ПРОГРАММ SPSS
Authors: Е.Е. Шарашова , К.К. Холматова , М.А. Горбатова , А.М. Гржибовский 
Published: November 2024

В статье представлены теоретические основы проведения двух методов анализа выживаемости для прогнозирования значения одной зависимой дихотомической переменной на основании одной или двух независимых за определенный временной интервал при использовании пакета прикладных статистических программ SPSS. На практических примерах описаны принципы проведения анализа Каплана-Мейера и использования таблиц дожития для одной и нескольких групп пациентов и варианты интерпретации полученной информации.
In this paper we present theoretical basis of the two methods of survival analysis for the prognosis of survival dependent on one or two independent variables during the time period with the use of SPSS software. We describe the main principles of Kaplan-Meier analysis and survival tables for one or several groups. Special emphasis is given to interpretation of the results and practical examples.
Мақалада SPSS қолданбалы статистиалық бағдарламалар пакетін пайдалану кезінде нақты уақыт арасында бір немесе екі тәуелсіздік негізінде бір тәуелді дихотомиялық ауыспалыны ңмәнін баолжау үшін өміршеңдікті талдаудың екі әдісін өткізудің теориялық негіздері көрсетілген. Бір немесе бінеше топтар үшін өміршеңдік кестелерін пайдалану мен Каплан –Мейерге талдау өткізу принциптері тәжірибелік үлгілерде суреттелген.