bluuebunny/crossref_metadata_2025_split huggingface dataset:
A model‐driven framework to enhance the consistency of logical integrity constraints: Introducing integrity regression testing
Authors: Nooraei Abadeh Maryam , Ajoudanian Shohreh 
Published: October 2018

SummaryAlthough the importance of models continuously grows in software development, common development approaches are less able to integrate the automatic management of model integrity into the development process. These critically important constraints may ensure the coherence of models in the evolution process to prevent manipulations that could violate defined constraints on a model. This paper proposes an integrity framework in the context of model‐driven architecture to achieve sufficient structural code coverage at a higher program representation level than machine code. Our framework offers to propagate the modifications from a platform‐independent specification to the corresponding test template model while keeping the consistency and integrity constraints after system evolution. To examine the efficiency of the proposed framework, a quantitative analysis plan is evaluated based on two experimental case studies. In addition, we propose coverage criteria for integrity regression testing (IRT), derived from logic coverage criteria that apply different conceptual levels of testing for the formulation of integrity requirements. The defined criteria for IRT reduce the inherent complexity and cost of verifying complex design changes in regression testing while keeping the fault detection capability with respect to the changes. The framework aims to keep pace with IRT in a formal way. The framework can solve a number of restricted outlooks in model integrity and some limiting factors of incremental maintenance and retesting. The framework satisfies several valuable quality attributes in software testing, such as safety percentage, precision, abstract fault detection performance measurable coverage level, and generality.
CD276 (B7-H3) Maintains Proliferation and Regulates Differentiation in Angiogenic Function in Late Endothelial Progenitor Cells
Authors: Son YeonSung , Kwon Sang-Mo , Cho Je-Yoel 
Published: October 2018

Abstract
Endothelial progenitor cells (EPCs) provide an important source of recovery from blood vessel dysfunction. Late EPCs (LEPCs) are circulating blood cells that are capable of promoting vascular repair. Using transcriptome analysis, we identified distinctive LEPC profiles and found that CD276 (B7-H3) mRNA is strongly expressed in LEPCs. CD276 protein is present abundantly on the cell surface of LEPC when analyzed by fluorescence-activated cell sorter and immunocytochemistry. CD276, a B7 family member, is a type I transmembrane glycoprotein. The role of CD276 in LEPCs remains unknown. CD276 knockdown by lentivirus transduction in LEPCs significantly decreased proliferation and increased apoptosis of LEPCs in vitro. After CD276 silencing, the cell cycle of LEPCs was prone to remain at the G0/G1 phase, and the cell migration rates as well as transwell and wound-healing migration were decreased. CD276 knockdown in LEPCs increased the G1 phase regulators cyclin D2/D3/E1-cyclin-dependent kinases (CDK2/4/6), but decreased the S-G2-M phase regulators cyclin A/B-CDK1. However, LEPCs with CD276 knockdown resulted in increased tube formation in vitro and angiogenesis in a Matrigel plug assay in vivo. FoxC1/C2, an upstream signal of Notch in arterial cell proliferation, and Hey1/2, which is known to promote arterial differentiation in the vasculature, were upregulated in CD276 knockdown LEPCs. In LEPCS, CD276 has a positive effect on proliferation and migration of endothelial cells, but negative effects on angiogenesis, particularly endothelial cell differentiation. Our data indicate, for therapeutic purpose, that CD276 can be used to acquire and maintain cell populations of LEPCs and blocking CD276 will promote angiogenetic differentiation. We found that CD276 (B7-H3) is enriched on the cell membrane of LEPCs. CD276 knockdown reduced proliferation and migration of LEPCs by increasing cell cycle inhibitors such as p21cip1 and pRb and decreasing pErk1/2 and pAkt but promoted angiogenesis and endothelial cell differentiation by elevating vascular endothelial growth factor-vascular endothelial growth factor receptor 1 and p-p38. Stem Cells 2019;37:382–394
Electromagnetic Relationship between Microwaves and Flow Reactor Systems
Authors: Sugiyama Jun‐ichi 
Published: October 2018

AbstractOne of the important points in handling microwaves is that the order of magnitude is decimeter order. Laboratory equipment is not too big for wavelength, so intensity nonuniformity may occur. Another important point is that microwave propagation changes with material parameter changes. To heat material in the planned shape, the consideration with electromagnetism about the equipment and the system will be necessary. Herein, the phenomena which should be considered when a flow reactor is irradiated with a microwave is described.
Narrative and Cognitive Modelling: Insights from Beckett Exploring Mind’s Complexity
Authors: Bernini Marco 
Published: October 2018

AbstractComplex systems exacerbate a common problem for scientific enquiry: the difficulty of creating models able to discriminate fundamental elements or patterns from random behaviours or corollary components in the event or process at issue. This chapter argues that a similar tension between order and randomness has been a chief modelling problem of Samuel Beckett’s narratives, tied to his interest in a specific kind of complex system (the mind) and its emergent properties (consciousness and the narrative sense of self). Bulding on narratology, complex system frameworks, cognitive theories of emergence and of scientific modelling, this chapter introduces the idea of “fictional cognitive modelling”. Through this concept, the chapter analyses Beckett’s treatment of narrative devices as formal tools for the creation of “exploratory models” able to atomise the emerging unity of conscious experience and of a narrative sense of self into its core components (defined as the “narrative dynamic core”). It concludes by suggesting that Beckett’s narrative method shows how literature can occupy a proper position in the investigation and exploration of complex systems.
On instabilities of scalar hairy regular compact reflecting stars
Authors: Peng Yan 
Published: October 2018

AbstractWe study the system constructed by charged scalar fields linearly coupled to asymptotically flat horizonless compact reflecting stars. We obtain bounds on the charge of the scalar field, below which the scalar hairy star is expected to suffer from nonlinear instabilities. It means that scalar hairy regular configurations are unstable for scalar fields of small charge. For the highly-charged star, there are also bounds on radii of regular compact reflecting stars. When the star radius is below the bound, the hairy star is always unstable.
Women and ‘the philosophical personality’: evaluating whether gender differences in the Cognitive Reflection Test have significance for explaining the gender gap in Philosophy
Authors: Easton Christina 
Published: October 2018

AbstractThe Cognitive Reflection Test (CRT) is purported to test our inclination to overcome impulsive, intuitive thought with effortful, rational reflection. Research suggests that philosophers tend to perform better on this test than non-philosophers, and that men tend to perform better than women. Taken together, these findings could be interpreted as partially explaining the gender gap that exists in Philosophy: there are fewer women in Philosophy because women are less likely to possess the ideal ‘philosophical personality’. If this explanation for the gender gap in Philosophy is accepted, it might be seen to exonerate Philosophy departments of the need to put in place much-needed strategies for promoting gender diversity. This paper discusses a number of reasons for thinking that this would be the wrong conclusion to draw from the research. Firstly, the CRT may not track what it is claimed it tracks. Secondly, the trait tracked by the CRT may not be something that we should value in philosophers. Thirdly, even if we accept that the CRT tracks a trait that has value, this trait might be of limited importance to good philosophising. Lastly, the causal story linking the gender gap in CRT score and the gender gap in Philosophy is likely to be far more complex than this explanation implies.
Gender differences in giving in the Dictator Game: the role of reluctant altruism
Authors: Klinowski David 
Published: October 2018

AbstractThe Dictator Game has been a helpful tool to study whether men or women are more generous. But recent work suggests that motivations other than generosity also influence behavior in this game. Image concerns and expectations management may cause dictators to “give reluctantly”; that is, to share money with the recipient if asked to, but to renege on their gifts if they can do so without being detected. We provide evidence from two separate experiments that females are more likely than males to give reluctantly in the Dictator Game. After accounting for retraction of gifts, males and females transfer similar amounts to the recipient in expectation. The results suggest that gender differences in non-payoff-related motivations may play a role in producing gender differences in giving in the Dictator Game.
The predictive capacity of DSM-5 symptom severity and impulsivity on response to cognitive-behavioral therapy for gambling disorder: A 2-year longitudinal study
Authors: Mestre-Bach Gemma , Steward Trevor , Granero Roser , Fernández-Aranda Fernando , del Pino-Gutiérrez Amparo , Mallorquí-Bagué Núria , Mena-Moreno Teresa , Vintró-Alcaraz Cristina , Moragas Laura , Aymamí Neus , Gómez-Peña Mónica , Sánchez-González Jéssica , Agüera Zaida , Lozano-Madrid María , Menchón José M. , Jiménez-Murcia Susana 
Published: October 2018

AbstractBackground:DSM-5 proposed a new operational system by using the number of fulfilled criteria as an indicator of gambling disorder severity. This method has proven to be controversial among researchers and clinicians alike, due to the lack of studies indicating whether severity, as measured by these criteria, is clinically relevant in terms of treatment outcome. Additionally, numerous studies have highlighted the associations between gambling disorder and impulsivity, though few have examined the impact of impulsivity on long-term treatment outcomes.Methods:In this study, we aimed to assess the predictive value of DSM-5 severity levels on response to cognitive-behavioral therapy (CBT) in a sample of male adults seeking treatment for gambling disorder (n = 398). Furthermore, we explored longitudinal predictors of CBT treatment response at a follow-up, considering UPPS-P impulsivity traits.Results:Our study failed to identify differences in treatment outcomes between patients categorized by DSM-5 severity levels. Higher baseline scores in negative urgency predicted relapse during CBT treatment, and higher levels of sensation seeking were predictive of drop-out from short-term treatment, as well as of drop-out at 24-months.Conclusions:These noteworthy findings raise questions regarding the clinical utility of DSM-5 severity categories and lend support to the implementation of dimensional approaches for gambling disorder.
Gender identities in adolescent population: Methodological issues and prevalence across age groups
Authors: Kaltiala-Heino Riittakerttu , Lindberg Nina 
Published: October 2018

AbstractBackground:Increasing numbers of adolescents are seeking treatment from gender identity services, particularly natal girls. It is known from survey studies some adolescents exaggerate their belonging to minorities, thereby distorting prevalence estimates and findings on related problems. The aim of the present study was to explore the susceptibility of gender identity to mischievous responding, and prevalences of cis-gender, opposite-sex and other/ non-binary gender identities as corrected for likely mischievous responding among Finnish adolescents.Method:The School Health Promotion Survey 2017 data was used, comprising data on 135,760 adolescents under 21 years (mean 15.73, ds 1.3 years), 50.6% females and 49.4% males. Sex and perceived gender were elicited and gender identities classified based thereon. Likely mischievous responding was analysed using inappropriate responses to biodata and handicaps.Results:Of the participants, 3.5% had most likely given facetious responses, boys more commonly than girls, and younger adolescents more commonly than older. This particularly concerned reporting of non-binary gender identity. Corrected prevalence of opposite-sex identification was 0.6% and that of non-binary identification was 3.3%. In boys, displaying non-binary gender identity increased from early to late adolescence, while among girls, opposite-sex and non-binary identifications decreased in prevalence from younger to older age groups.Conclusion:Prevalence of gender identities contrary to one’s natal sex was more common than expected.
Still ‘Minding the Gap’ Sixteen Years Later: (Re)Storying Pro-Environmental Behaviour
Authors: Siegel Lisa , Cutter-Mackenzie-Knowles Amy , Bellert Anne 
Published: October 2018

AbstractIn their seminal 2002 paper, Kollmuss and Agyeman asked the important question ‘Why do people act environmentally and what are the barriers to pro-environmental behaviour?’ The article has had a remarkably high rate of readership, with 64,900 electronic views to date, and 16 years later, this question remains significant. But are environmental educators and researchers any closer to understanding why people engage in pro-environmental behaviour? For this special issue of theAustralian Journal of Environmental Educationand its focus on ecologising education, it is timely not only to re-explore but to (re)story the concepts of environmental knowledge, environmental awareness and pro-environmental behaviour, in order to generate fertile ground for the creation of new understandings and practices in environmental education. After considering relevant literature published between 2000 and 2018, this article offers an original framework for considering the complex, varied, and interconnected influences on the development of pro-environmental behaviour by (re)storying the development of pro-environmental behaviour through articulating it as a living forest.
Coupled aeropropulsive design optimisation of a boundary-layer ingestion propulsor
Authors: Gray Justin S. , Martins Joaquim R. R. A. 
Published: October 2018

AbstractAirframe–propulsion integration concepts that use boundary-layer ingestion (BLI) have the potential to reduce aircraft fuel burn. One concept that has been recently explored is NASA’s STARC-ABL aircraft configuration, which offers the potential for fuel burn reduction by using a turboelectric propulsion system with an aft-mounted electrically driven BLI propulsor. So far, attempts to quantify this potential fuel burn reduction have not considered the full coupling between the aerodynamic and propulsive performance. To address the need for a more careful quantification of the aeropropulsive benefit of the STARC-ABL concept, we run a series of design optimisations based on a fully coupled aeropropulsive model. A 1D thermodynamic cycle analysis is coupled to a Reynolds-averaged Navier–Stokes simulation to model the aft propulsor at a cruise condition and the effects variation in propulsor design on overall performance. A series of design optimisation studies are performed to minimise the required cruise power, assuming different relative sizes of the BLI propulsor. The design variables consist of the fan pressure ratio, static pressure at the fan face, and 311 variables that control the shape of both the nacelle and the fuselage. The power required by the BLI propulsor is compared with a podded configuration. The results show that the BLI configuration offers 6–9% reduction in required power at cruise, depending on assumptions made about the efficiency of power transmission system between the under-wing engines and the aft propulsor. Additionally, the results indicate that the power transmission efficiency directly affects the relative size of the under-wing engines and the aft propulsor. This design optimisation, based on computational fluid dynamics, is shown to be essential to evaluate current BLI concepts and provides a powerful tool for the design of future concepts.
Clinical research coordinators’ instructional preferences for competency content delivery
Authors: Kolb H. Robert , Kuang Huan , Behar-Horenstein Linda S. 
Published: October 2018

IntroductionA lack of standardized clinical research coordinator (CRC) training programs requires determining appropriate approaches for content delivery. The purpose of this study was to assess CRCs preferred training delivery methods related to the 8 designated Joint Task Force Clinical Trial Competency domains.MethodsRepeated measures analysis of variance and split-plot analysis of variance were adopted to compare the group means among 5 training delivery methods by 8 competency content domains and to examine whether demographic variables caused different preference patterns on the training delivery methods.ResultsParticipants reported a preference for online video; mentoring/coaching was the least preferred. Significant training delivery method preferences were reported for 3 content domains: participant safety considerations, medicines development and regulation, and clinical trials operations.DiscussionObserved statistical differences in the training delivery methods by the content domains provides guidance for program development. Ensuring that standardized educational training is aligned with the needs of adult learners may help ensure that CRCs are appropriately prepared for the workforce.
Simulating climatic mass balance, seasonal snow development and associated freshwater runoff in the Kongsfjord basin, Svalbard (1980–2016)
Authors: PRAMANIK ANKIT , VAN PELT WARD , KOHLER JACK , SCHULER THOMAS V. 
Published: October 2018

ABSTRACTThe Kongsfjord basin in northwest Svalbard is the site of a number of interdisciplinary studies concerned with the effect of fresh water from seasonal snow and glacier melt on the physical and biological environment. We use an energy-balance model coupled with a subsurface snow model to simulate the long-term climatic mass-balance evolution of the glaciers and the seasonal snow development of nonglacierized parts of the Kongsfjord basin. Runoff from both glacierized and nonglacierized parts of the basin is simulated to quantify the fresh water flux to the fjord. The model is calibrated with long-term mass-balance data measured at four glaciers, and with automatic weather station data. The simulated area-averaged climatic mass balance for the whole basin is positive (+0.23 m w.e. a−1) over the period 1980–2016; however, the trend for net mass balance is not statistically significant over the simulation period, despite the observed ongoing summer warming. Refreezing equals 0.24 m w.e. a−1, which is equivalent to 17% of the total mass gain from precipitation and moisture deposition. Total runoff comprises contributions from seasonal snow in the nonglacierized area (16%) and glacier discharge (84%). Model time series shows a significant increasing trend for annual glacier runoff (6.83 × 106 m3 a−1) over the simulation period.
Ice-rise stratigraphy reveals changes in surface mass balance over the last millennia in Dronning Maud Land
Authors: GOEL VIKRAM , MARTÍN CARLOS , MATSUOKA KENICHI 
Published: October 2018

ABSTRACTWe use ice flow modelling to simulate the englacial stratigraphy of Blåskimen Island, an ice rise in Dronning Maud Land and elucidate the evolution of this data-sparse region. We apply a thermo-mechanically coupled Elmer/Ice model to a profile along flowlines and through the ice-rise summit, where surface mass balance (SMB), flow velocity and ice stratigraphy were recently measured. We conclude that: (i) the ice rise is presently thickening at a rate of 0.5~0.6 m ice equivalent per year (mieq a−1), which is twice an earlier estimate using the field data and the input–output method; (ii) present thickening started 20–40 years in the past, before which the ice rise was in a steady state; (iii) SMB contrast between the upwind and downwind slopes was stronger than the present value by ~23% (or 0.15 mieq a−1) prior to ~1100 years ago. Since then, this contrast has been decreasing overall. We surmise that these SMB changes are likely a result of synoptic-scale atmospheric changes, rather than local atmospheric changes controlled by local ice topography. Our technique effectively assimilates geophysical data, avoiding the complexity of ice flow beneath the ice divide. Thus, it could be applied to other ice rises to elucidate the recent glacial retreat.
Does Blind Tasting Work? Investigating the Impact of Training on Blind Tasting Accuracy and Wine Preference
Authors: Wang Qian Janice , Prešern Domen 
Published: October 2018

AbstractWe analyzed data from Oxford University Blind Tasting Society's 2018 training season to assess whether blind tasting training improves accuracy. Over time, guesses for grape variety increased in terms of accuracy as well as within-group agreement. Moreover, for grape variety, location, and vintage, the chances of the most common within-group guess being correct were significantly higher than the underlying frequency distribution. Finally, we observed a shift in preference towards older wines, with those with little initial experience gaining a preference for greater acidity and alcohol, and decreasing their preference for oak. Our results have important implications for growing wine markets with an increasingly educated consumer population. (JEL Classifications: C91, C92, D83, L15, L66).
Early deglaciation and paleolake history of Río Cisnes Glacier, Patagonian Ice Sheet (44°S)
Authors: García Juan-Luis , Maldonado Antonio , de Porras María Eugenia , Nuevo Delaunay Amalia , Reyes Omar , Ebensperger Claudia A. , Binnie Steven A. , Lüthgens Christopher , Méndez César 
Published: October 2018

AbstractThe timing, structure, and landscape change during the Patagonian Ice Sheet deglaciation remains unresolved. In this article, we provide a geomorphic, stratigraphic, and geochronological deglacial record of Río Cisnes Glacier at 44°S and also from the nearby Río Ñirehuao and Río El Toqui valleys (45°S) in Chilean Patagonia. Our 14C, 10Be, and optically stimulated luminescence data indicate that after the last glacial maximum, Río Cisnes Glacier experienced ~100 km deglaciation between >19.0 and 12.3 ka, accompanied by the formation of large glacial paleolakes. Deglaciation was interrupted by several ice readvances, and by 16.9±0.3 ka, Río Cisnes Glacier extended only ~40% of its full glacial extent. The deglaciation of Río Cisnes Glacier and other sensitive Patagonian glaciers occurred at least 1 ka earlier than the ca. 17.8 ka normally assumed for the local termination, coincident with West Antarctic isotope records. This early deglaciation can be linked to an orbital forcing–driven decline of Southern Ocean sea ice associated with a distinct atmospheric warming that is apparent for West Antarctica through Patagonia.