bluuebunny/crossref_metadata_2025_split huggingface dataset:
Could the Boom‐Bust in the Eurozone Periphery Have Been Prevented?
Authors: Bielecki Marcin , Brzoza‐Brzezina Michał , Kolasa Marcin , Makarski Krzysztof 
Published: October 2018

AbstractBoom‐bust cycles in the eurozone periphery almost toppled the single currency and recent experience suggests that they may return soon. We check whether monetary or macroprudential policy could have prevented the periphery's violent boom and bust after the euro adoption. We estimate a DSGE model for the two euro area regions, core and periphery, and conduct a series of historical counterfactual experiments in which monetary and macroprudential policy follow optimized rules that use area‐wide welfare as the criterion. We show that single monetary policy could have better stabilized output in both regions, but not the housing market or the periphery's trade balance. In contrast, region‐specific macroprudential policy could have substantially smoothed the credit cycle in the periphery and reduced the build‐up of external imbalances.
Overcoming barriers to diabetes care in the hospital: The power of qualitative observations to promote positive change
Authors: Pichardo‐Lowden Ariana , Farbaniec Michelle , Haidet Paul 
Published: October 2018

AbstractAimsDespite advocacy by diabetes societies and evidence about how to prevent the deleterious consequences of dysglycemia among hospitalized patients, deficits in clinical practice continue to present barriers to care. The purpose of this study was to examine inpatient rounding practices using a qualitative research lens to assess challenges on the care of hospitalized patients with diabetes and to develop ideas for positive changes in hospital management of diabetes and hyperglycemia.MethodsWe conducted an interpretive analysis of qualitative observations during medical and surgical inpatient rounds at an academic institution. We coded, analysed, and reported data as thematic findings.ResultsEmerging themes include omissions in discussions during rounds; unpreparedness to address diabetes or dysglycemia during rounds; identifying practice improvement opportunities to address diabetes issues: and recognizing accountability within the routine of practice.ConclusionsThis work guides clinicians and informs systems of practice about improvement strategies that can emerge from within hospital teams. These recommendations emphasize the interconnectedness of practice elements including thoughtful review of glucose status during rounds among patients with and without diabetes; fostering doctors and nurses to work in unison; promoting awareness and integration within and across disciplines; and advocating for better use of existing resources.
Intelligent models based nonlinear modeling for infrared drying of mahaleb puree
Authors: Isleroglu Hilal , Beyhan Selami 
Published: October 2018

AbstractIn this article, nonlinear regressor models namely polynomial regressor, artificial neural‐network (ANN) and least‐squares support vector machine (LS‐SVM) were designed and applied to model the drying kinetics and change of the antioxidant properties of mahaleb puree during infrared drying process. Temperature and time were used as the model inputs and moisture ratio, antioxidant capacity and total anthocyanin content were the outputs of nonlinear regressors. The regressor models were compared in terms of the root mean‐squared‐error (RMSE) and minimum‐descriptive‐length (MDL) criteria. According to statistical selection criteria, LS‐SVM was the best model to describe the infrared drying kinetics of mahaleb puree with the lowest RMSE and MDL values. ANN with Levenberg‐Marquardth optimization gave the best results to predict antioxidant capacity and total anthocyanin content during infrared drying process of mahaleb puree.Practical applications(a) Design and analysis of intelligent models for modeling of drying processes. (b) Design of automatic drying equipments by embedding intelligent models. (c) Prediction of moisture ratio, antioxidant capacity and total anthocyanin of drying mahaleb puree at any time and temperature.
Iron‐induced energy supply deficiency and mitochondrial fragmentation in neurons
Authors: Huang Xiao Tian , Liu Xing , Ye Chun Yan , Tao Ling Xue , Zhou Hu , Zhang Hai Yan 
Published: October 2018

AbstractIron dyshomeostasis and mitochondrial impairments are both vitally important for the progression of many neurodegenerative diseases, including Parkinson's disease and Alzheimer's disease. Nevertheless, how these two pathological phenomena are linked with one another remains unclear, especially in neurons. To address the question, a model of iron overload was established with exposure of rat primary cortical neurons to excessive iron. We first verified that iron overload resulted in a decrease in adenosine triphosphate (ATP) production in neurons. Meanwhile, the release of mitochondrial cytochrome c was significantly increased after iron overload and consequently triggered an apoptosis signal, as revealed by Caspase 3 cleavage. To explore the potential underlying molecular mechanisms, an unlabeled quantitative proteomics approach was applied to primary neurons. Gene Ontology enrichment analysis revealed that 58 mitochondria‐associated proteins were significantly altered, including three subunits of mitochondrial complex I and optic atrophy 1(OPA1). Increased NADH‐ubiquinone oxidoreductase 75 kDa subunit and decreased NADH‐ubiquinone oxidoreductase subunit A10 levels were further validated by a western blot, and more importantly, complex I activity markedly declined. Iron‐induced down‐regulation on the OPA1 level was also validated by a western blot, which was not reversed by the anti‐oxidant but was reversed by the iron chelator. Moreover, an OPA1‐associated key downstream effect, mitochondrial fragmentation, was found to be aggravated in neurons exposed to excessive iron, which is consistent with the down‐regulation of OPA1. Furthermore, the protein level of PTEN‐induced putative kinase 1, an important protein closely related to complex I activity and mitochondrial fragmentation, also significantly declined in neurons by iron overload. Thus, our findings may shed new light on the linkage between iron toxicity and mitochondrial impairments, such as energy supply deficiency and mitochondrial fragmentation, and further expand the toxic repertoire of iron in the central nerve system.
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Cover Image for this issue: doi: 10.1111/jnc.14205.
Description of a new diatom genus Dorofeyukea gen. nov. with remarks on phylogeny of the family Stauroneidaceae
Authors: Kulikovskiy Maxim , Maltsev Yevhen , Andreeva Svetlana , Glushchenko Anton , Gusev Evgeniy , Podunay Yulia , Ludwig Thelma Veiga , Tusset Eduardo , Kociolek John Patrick 
Published: October 2018

Type material of Navicula kotschyi was studied, and this species was transferred to Dorofeyukea gen. nov. as D. kotschyi comb. nov. Dorofeyukea was described on the basis of DNA sequence and morphological data. Additional species assigned to this genus that were previously included in Navicula include: D. ancisa comb. nov., D. grimmei comb. nov., D. ivatoensis comb. nov., D. orangiana comb. nov., D. rostellata comb. nov. & stat. nov., D. savannahiana comb. nov., D. tenuipunctata comb. nov., and D. texana comb. nov. All Dorofeyukea species share the same morphological features, including having a narrow stauroid fascia surrounded by 1–3 irregularly shortened striae, uniseriate, and weakly radiate striae, circular, or rectangular puncta in the striae that are covered internally by dome‐shaped hymenes, presence of a pseudoseptum at each apex and absence of septa. Partial DNA sequences of SSU and rbcL loci show Dorofeuykae belongs to the clade of stauroneioid diatoms together with Stauroneis, Prestauroneis, Craticula, Karayevia, Madinithidium, Fistulifera, Parlibellus, and, possibly, Schizostauron. A new species from the monoraphid genus Madinithidium, M. vietnamica sp. nov., was described based on valve and chloroplast morphology as well as DNA sequence data.
A computational fluid dynamics (CFD) based method for assessing the hydrodynamic impact of animal borne data loggers on host marine mammals
Authors: Kyte Adam , Pass Christopher , Pemberton Richard , Sharman Matthew , McKnight J. Chris 
Published: October 2018

AbstractAnimal‐borne data loggers (ABDLs) or “tags” are regularly used to elucidate animal ecology and physiology, but current literature highlights the need to assess associated deleterious impacts including increased resistive force to motion. Previous studies have used computational fluid dynamics (CFD) to estimate this impact, but many suffer limitations (e.g., inaccurate turbulence modeling, neglecting boundary layer transition, neglecting added mass effects, and analyzing the ABDL in isolation from the animal).A novel CFD‐based method is presented in which a “tag impact envelope” is defined utilizing simulations with and without transition modeling to define upper and lower drag limits, respectively, and added mass coefficients are found via simulations with sinusoidally varying inlet velocity, with modified Navier‐Stokes conservation of momentum equations enforcing a shift to the animal's noninertial reference frame. The method generates coefficients for calculating total resistive force for any velocity and acceleration combination, and is validated against theory for a prolate spheroid. An example case shows ABDL drag impact on a harp seal of 11.21%–16.24%, with negligible influence on added mass.By considering the effects of added mass and boundary layer transition, the approach presented is an enhancement to the CFD‐based ABDL impact assessment methods previously applied by researchers.
A calibrated model of local food system of Hawaii: What are the economic implications of the state's food goals and policies?
Authors: Khan Syed S. , Arita Shawn , Howitt Richard , Leung PingSun 
Published: October 2018

AbstractWe develop a fully calibrated positive mathematical programming model for Hawaii's local food systems—which captures the production and the consumer sides of the market. Then we use the model to assess two proposed policies—a general excise tax (GET) exemption on locally produced foods, and an investment in agricultural infrastructure. For the GET exemption case, our results indicate an economic gain of $118 per $100 cost. On the other hand, an investment in 1,200 acres of land injected to support local production may generate an economic gain of up to $357 per $100 annual cost of the investment. However, these estimates should be considered preliminary, and thus viewed with caution. Although the model is used to capture Hawaii's local food systems, we believe that our model is generalizable and can be adopted by other economies to assess their respective food localization policies.Recommendations for Resource Managers

Local food policies need to be based on quantitative terms instead of mere armchair speculation because often their potential outcomes may vary significantly.

The current modeling framework demonstrates the potential of using positive mathematical programming (PMP) in capturing the intricacies of local food systems. However, this exploratory exercise should be viewed as preliminary in nature and the ensuing results were taken with caution because many important factors such as labor availability may have been left out.

Thus, further model refinements are necessary to better capture the complexities of local food systems such as farm heterogeneity, availability of farm labor, water availability, and interisland transportation of farm products in the case of Hawaii.
Forecast Evaluation Under Asymmetric Loss: A Monte Carlo Analysis of the EKT Method
Authors: Krüger Jens J. , LeCrone Julian 
Published: October 2018

AbstractThis paper contributes to the literature on forecast evaluation by conducting an extensive Monte Carlo experiment using the evaluation procedure proposed by Elliott, Komunjer and Timmermann. We consider recent developments in weighting matrices for GMM estimation and testing. We pay special attention to the size and power properties of variants of the J‐test of forecast rationality. Proceeding from a baseline scenario to a more realistic setting, our results show that the approach leads to precise estimates of the degree of asymmetry of the loss function. For correctly specified models, we find the size of the J‐tests to be close to the nominal size, while the tests have high power against misspecified models. These findings are quite robust to inducing fat tails, serial correlation and outliers.
Herbivory elicits changes in green leaf volatile production via jasmonate signaling and the circadian clock
Authors: Joo Youngsung , Schuman Meredith C. , Goldberg Jay K. , Wissgott Antje , Kim Sang‐Gyu , Baldwin Ian T. 
Published: October 2018

AbstractThe timing of plant volatile emissions is important for a robust indirect defense response. Green leaf volatiles (GLVs) are emitted by plants upon damage but can be suppressed by herbivore‐associated elicitors, and the abundance and composition of GLVs vary depending on the timing of herbivore attack. We show that the GLV biosynthetic enzymeHYDROPEROXIDE LYASE(HPL) is transcriptionally regulated by the circadian clock inNicotiana attenuata. In accordance with transcript abundance ofNaHPL, GLV aldehyde pools in intact leaves peaked at night and at subjective night under diurnal and continuous light conditions, respectively. Moreover, although the basal abundance ofNaHPLtranscripts is upregulated by jasmonate (JA) signaling, JA does not regulate the reduction ofNaHPLtranscript abundance in damaged leaves by simulated herbivore treatment. Unexpectedly, the plant circadian clock was strongly altered whenManduca sextalarvae fed onN. attenuata, and this was also independent of JA signaling. Lastly, the temporal dynamics ofNaHPLtranscripts and total GLV emissions were strongly altered byM. sextalarval feeding. Our data suggest that the temporal dynamics of emitted GLV blends result from a combination of damage, JA signaling, herbivore‐associated elicitors, and the plant circadian clock.
The post‐gay debates: Competing visions of the future of homosexualities
Authors: Kampler Benjamin , Connell Catherine 
Published: October 2018

AbstractSexualities scholars and cultural critics debate whether or not the United States is moving toward a “post‐gay” future in which sexual orientation will cease to be relevant to a person's social position, life experiences, and conception of self. While some have argued that a post‐gay revolution is underway, others are more skeptical of this claim, particularly for rural, non‐White, poor, and otherwise marginalized queers. Further, recent political shifts may indicate that a backlash to the mainstreaming of nonheterosexualities has begun, meaning any progress of the past that might be labeled post‐gay has stalled or even lost ground in recent years. In addition to the question of whether there has been a post‐gay turn, there is disagreement over whether such a turn should be the end goal of sexualities activism. Some champion a post‐gay ethos as a means to alleviate sexuality‐based discrimination while others critique this kind of assimilation and argue it actually intensifies inequality and stratification. This article explores the history of these post‐gay debates and discovers significant conceptual confusion inherent in the use of the term, which limits its utility as a social scientific concept. In addition, we argue that despite the better intentions of some scholars who take it, the post‐gay position ultimately buttresses homonormative strategies of social and political activism that actively exclude marginalized queer and trans people. We suggest that to the extent the concept of post‐gay remains academically relevant, it is as a descriptor of a particular politics or discourse rather than as a statement of fact about the contemporary era.
Verb Movement in Narrow Syntax
Authors: Hosono Mayumi 
Published: October 2018

AbstractI argue that verb movement should be derived in narrow syntax. The derivational system ofLabeling Algorithmproposed by Chomsky (2013, 2015) allows movement to occur in narrow syntax without recourse to any movement‐triggering features, contra Chomsky (2001, 2004, 2008). In this system, (both external and internal) Merge is free, even if a new semantic effect does not occur on a raised category in its raised position, contra Chomsky (2001). Thus, verb movement, which does not change a semantic interpretation in the unmarked case, should be able to occur in narrow syntax without recourse to any driving features. As we see in the Icelandic data, it is actually difficult to claim that verb movement occurs in phonology, contra Chomsky (2001). I propose a way to carry out verb movement in narrow syntax in terms offeature inheritanceandcopy deletion. In the Romance languages as well as languages such as English, both φ‐features and tense are inherited by T, to which R(=V)+v* moves, whereas in the V2 languages, only φ‐features are inherited by T with tense remaining in C, to which R+v* directly moves. In all of those languages, it is a matter of morphophonology which copy of a verbal head, the one in a higher position or the one in the v* head position, is chosen to be pronounced. I also claim thatdois inserted in English to phonetically embody features such as [Q], [Foc(us)] and [Pol(arity)]. The feature that the inserteddoembodies is adjacent to tense and φ‐features in each of the relevant constructions, which accounts for why the inserteddocarries tense and agreement as pointed out by the traditional literature.
Dispersal and speciation of East African mountain bushcrickets of the genus Phlesirtes (Orthoptera: Tettigoniidae: Conocephalinae, Conocephalini) related to climate fluctuations
Authors: Hemp Claudia , Kuechler Stefan M. , Kehl Siegfried , Waegele Johann W. , Hemp Andreas 
Published: October 2018

AbstractA phylogeny of the genus Phlesirtes Bolivar is presented, based on new sequence data of three genes (16S rDNA, COI, H3). Species of the genus Phlesirtes (subtribe Karniellina of the Tribe Conocephalini) occupy habitats of montane to afroalpine grasslands in East Africa. Phlesirtes is the most species‐rich genus of the subtribe Karniellina, a group of small flightless Ensifera restricted to eastern Africa. Taken together, the biogeographical patterns seen in Phlesirtes and its molecular phylogeny suggest a migration scenario: the mountain ranges acting as stepping stones, enabling a spread of Phlesirtes ancestors during periods of favourable climatic conditions in the past. The Pleistocene inland volcanoes, such as Mt Kenya or Mt Kilimanjaro, allow us to date speciation processes within the genus Phlesirtes. It is suggested that cooler humid periods of the past 3 Ma boosted speciation of Phlesirtes in East Africa.
Serum IgE cross‐reactivity between fish and chicken meats in dogs
Authors: Bexley Jennifer , Kingswell Nicola , Olivry Thierry 
Published: October 2018

BackgroundIn humans, a cross‐reactive clinical allergy has been reported between three chicken and fish meat proteins: beta‐enolase, aldolase A and parvalbumin.ObjectiveTo evaluate if IgE cross‐reactivity between chicken and fish also existed in the dog.AnimalsSera from dogs with suspected allergic skin disease and with IgE against chicken and fish.Methods and materialsSera were analysed by ELISA and immunoblotting with chicken, white fish (haddock and cod) and salmon extracts. Reciprocal inhibition ELISAs and inhibition immunoblots were then performed. Protein sequencing of bands identified on multiple extracts was determined by mass spectrometry.ResultsOut of 53 archived canine sera tested by ELISA against chicken, white fish or salmon, 15 (28%), 12 (23%) and 26 (49%), respectively, had elevated IgE against one, two or all three of these extracts. Seven of the triple‐reactive sera were subjected to reciprocal inhibition ELISAs. A >50% inhibition was found between chicken–fish, chicken–salmon and fish–salmon in seven, four and five of seven dogs, respectively. Immunoblotting identified multiple IgE‐binding proteins of identical molecular weights in the three extracts; these were partially to fully cross‐reactive by inhibition immunoblotting. Mass spectrometry identified nine cross‐reactive proteins as: pyruvate kinase, creatine kinase, alpha‐actin, glyceraldehyde‐3‐phosphate dehydrogenase, beta‐enolase, aldolase, malate dehydrogenase, lactate dehydrogenase and triose‐phosphate isomerase 1. All of these have been reported previously as fish, shellfish and/or chicken allergens for humans.Conclusions and clinical importanceWhether any of these newly identified IgE cross‐reactive chicken–fish allergens is the cause of clinical allergy needs to be determined in dogs reacting to at least two of these common food sources.
The use of absorbable staples for skin closure after tibial plateau leveling osteotomy
Authors: Watson F. C. , McMullan W. , Jordan C. J. , Egan P. , Tuan J. , Solano M. A. , Fizpatrick N. 
Published: October 2018

AbstractObjectiveTo compare the use of stainless steel staples with absorbable staples for closure of skin incisions in dogs undergoing tibial plateau leveling osteotomy (TPLO).Study designProspective study.Sample populationClient‐owned dogs (n = 80).MethodsWith client consent, dogs were randomly assigned a staple type (stainless steel or absorbable) immediately prior to closure of a TPLO skin incision. Incisions were compared for length, staple type and number, and an inflammation‐infection score 2 weeks after surgery.ResultsOverall, 18.8% of incisions were diagnosed with inflammation or infection. No difference was found between inflammation‐infection scores, incision length, number of staples used, or general anesthetic time between the 2 staple groups. However, wound closure was faster with stainless steel staples (22.50 seconds; range, 11‐180) by approximately 30 seconds compared with absorbable staples (56.50 seconds; range, 18‐190;P < .001). Time taken to close the incision correlated negatively with the number of occasions that absorbable staples were used (P = .01).ConclusionAbsorbable skin staples were successfully used to close skin incisions after TPLO and were not associated with an increased level of inflammation or infection in our clinical setting.Clinical significanceAbsorbable staples may be considered to close surgical wounds when subsequent suture removal would be impractical, without specific concerns over inflammation or infection of the wound.