bluuebunny/crossref_metadata_2025_split huggingface dataset:
Controllable synthesis and enhanced photocatalytic activity of B‐TiO2 nanospheres
Authors: Wang Shumin , Yan Xiaoxia , Deng Dongmei , He Haibo , Lei Yunyi , Shen Xia , Luo Liqiang 
Published: March 2019

A series of boron‐doped‐titanium dioxide (B‐TiO2) nanospheres were synthesised via a mild and facile spray‐drying process. The obtained nanospheres were relatively uniform with a size of about 100 nm. A strong absorption in the visible‐light range was observed due to the formation of Ti–O–B bonds, by narrowing the bandgap of B‐TiO2 from 3.1 to 2.8 eV. The as‐synthesised 3 wt% B‐TiO2 exhibited the greatest photocatalytic activity in the degradation of p‐nitrophenol. The photocatalytic performance was improved, which could be attributed to high absorption of the visible‐light region and efficient separation of photogenerated electron–hole pairs.
Langzeiterfahrung mit Collagenase Clostridium Histolyticum
(CCH, Xiapex®) zur Behandlung der Dupuytrenschen Kontraktur: Lessons
learned
Authors: Neuwirth Maximilian , Kalt Lukas , Pipam Wolfgang , Rab Matthias 
Published: March 2019

Zusammenfassung
Einleitung Neben den klassischen Therapieverfahren konnte sich CCH
(Collagenase Clostridium Histolyticum; Xiapex®) zur Behandlung der
Dupuytrenschen Kontraktur als einfache und zuverlässige Therapiealternative
etablieren. Ziel dieser Arbeit war die Analyse unserer Ergebnisse sowie die
Diskussion der von uns durchgeführten Modifikationen in der Anwendung.
Patienten und Methoden In die Studie eingeschlossen wurden 312 Finger, die
zwischen 2011 und 2018 mittels CCH behandelt wurden (256 Patienten; 225 Männer;
31 Frauen). Bei 157 Fingern (50,3 %) lag eine isolierte Gelenkskontraktur vor,
wohingegen bei 155 Fingern (49,7 %) multiple Gelenke betroffen waren. Das
Durchschnittsalter zum Zeitpunkt der Intervention lag bei 65,8 Jahren. Der
durchschnittliche Nachuntersuchungszeitraum betrug 41,2 Wochen. Im Rahmen einer
retrospektiven Datenanalyse wurden die von uns erzielten Ergebnisse ausgewertet
und der Einfluss der von uns durchgeführten technischen Modifikationen auf den
Therapieerfolg diskutiert.
Ergebnisse Der durchschnittliche, präinterventionelle Kontrakturgrad lag
bei 63,3 Grad. Die durchschnittliche Kontrakturreduktion zum Ausgangsbefund
betrug unmittelbar postinterventionell 94 % sowie 81 % zum Zeitpunkt der letzten
Nachuntersuchung. Hauteinrisse traten in 22,1 % auf. In 99,4 % zeigte sich ein
unauffälliger Behandlungsverlauf (minor Komplikationsrate: 0,6 %). Die
Rezidivrate lag bei 14,4 %. Die Verlängerung des Zeitintervalls zur Aufdehnung
(24 vs. 48 Stunden) zeigte keinen wesentlichen Einfluss auf die unmittelbare
Erfolgsrate sowie die Rate an Hautläsionen.
Schlussfolgerung Bei richtiger Indikationsstellung sowie routinierter
Anwendung ist die Erfolgsrate von CCH mit jener der gängigen
Therapiealternativen vergleichbar.
Detachable string magnetically controlled capsule endoscopy for complete viewing of the esophagus and stomach
Authors: Chen Yi-Zhi , Pan Jun , Luo Yuan-Yuan , Jiang Xi , Zou Wen-Bin , Qian Yang-Yang , Zhou Wei , Liu Xiao , Li Zhao-Shen , Liao Zhuan 
Published: March 2019

Abstract
Background Esophageal capsule endoscopy is reported to be insufficiently accurate to replace esophagogastroduodenoscopy (EGD) because the passage of the capsule through the esophagus is passive and precludes a thorough investigation. We developed a modified capsule endoscopy technique, called detachable string magnetically controlled capsule endoscopy (DS-MCE), and performed a pilot study to assess the feasibility and safety of this novel technique.
Methods 4 healthy volunteers and 21 patients with suspected esophageal disease first underwent DS-MCE followed by EGD within 1 week. Outcomes included technical success of DS-MCE, adverse events, discomfort, and diagnostic accuracy.
Results DS-MCE was successfully carried out in all 25 participants. No adverse events were observed. Mean overall discomfort score during DS-MCE was 0.96 (range 0 – 3). DS-MCE diagnoses were in accordance with EGD in all 25 participants. The per-patient sensitivity of DS-MCE for esophageal disease detection was 100 %. The accuracy of DS-MCE for grading esophageal varices and reflux esophagitis were 66.7 % and 100 %, respectively.
Conclusions DS-MCE was a feasible, safe, and well-tolerated method for viewing the esophagus and proceeding with gastric examination after string detachment.
Una masa renal poco común en una adolescente – presentación de caso y revisión de la literatura
Authors: Santafé Galvis Jhonatan Sair , Cruz Arévalo Dilma Alexandra , Salgado Tovar Javier Mauricio 
Published: March 2019

Introducción Las neoplasias renales en la población pediátrica y adolescente son raras, entre el 6% y el 7% de las masas en pediatría. En adolescentes plantea un desafío clínico importante. Presentan variables manifestaciones sistémicas inespecíficas o cuadros asintomáticos. En la literatura se han identificado el Carcinoma de Células Renales y el Tumor de Wilms como las masas renales más prevalentes en menores de 20 años, el Adenoma Metanéfrico es una entidad muy poco común en esa población.
Presentación de caso Adolescente, con dolor en flanco izquierdo y hematuria macroscópica monosintomática, estudios imagenológicos evidencian lesión de aspecto neoplásico renal izquierda, que al complementarse con estudios de inmunohistoquímica resulta en Adenoma Metanéfrico. Se realiza revisión de literatura publicada en las últimas tres décadas al respecto. La paciente es llevada a nefrectomía radical izquierda, y posteriormente el estudio anatomopatológico sugiere Adenoma Metanéfrico, con marcadores de inmunohistoquímica que corroboran el hallazgo.
Conclusiones Los tumores renales en adolescentes son raros. Se requiere de alta sospecha clínica, un examen físico meticuloso y el apoyo en imágenes diagnósticas. Generalmente, el estudio histopatológico determina el diagnóstico definitivo, no obstante, cuando persiste la confusión, se recurre a la inmunohistoquímica. El Carcinoma de Células Renales es el más prevalente de los tumores renales en adolescentes, pero existen entidades indistinguibles al estudio imagenológico que plantean un desafío clínico; es el objetivo brindar una herramienta de apoyo en el abordaje del Adenoma metanéfrico e instar al desarrollo de conocimiento sobre una entidad patológica en ese grupo etario que ha sido poco documentado que indudablemente redundará en mejores prácticas e impacto científico, social y económico.
Postpartum Depression: Epidemiological Clinical Profile of Patients Attended In a Reference Public Maternity in Salvador-BA
Authors: Araújo Ivan de Sousa , Aquino Karolina Sales , Fagundes Luciana Kelly Amado , Santos Vanessa Cruz 
Published: March 2019

Objective To evaluate the clinical epidemiological state of women with suspected postpartum depression (PPD) in a public maternity hospital in Salvador, state of Bahia, Brazil.
Methods A cross-sectional research was performed with puerperal patients attended at a public maternity hospital in Salvador, Bahia. Data collection was performed from June to September 2017. The Edinburgh Postnatal Depression Scale was used as a screening instrument, and, subsequently, women with positive scores answered a questionnaire to identify their clinical and epidemiological status.
Results Out of 151 postpartum women from the research, 30 (19.8%) presented suspicion of PPD. There was a prevalence of single mothers 13 (43.3%), women with complete fundamental education 15 (50.0%), women with black skin color 14 (46.7%), and those with a monthly family income of up to one minimum wage 18 (40.0%).
Conclusion Although PPD is an underdiagnosed disease, a high prevalence of the condition was found in our research. It is, then, considered that these results reinforce its significance as a public health problem, requiring prevention strategies, early diagnosis and effective treatment.
Quality of Life in Women with Defecatory Dysfunctions: Systematic Review of Questionnaires Validated in the Portuguese Language
Authors: Vasconcelos Neto José Ananias , Vasconcelos Camila Teixeira Moreira , Karbage Sara Arcanjo Lino , Farias Hérdeny Di Cárlly de Almeida Rocha , Machado Stéffany Gadelha de Macêdo , Saboia Dayana Maia 
Published: March 2019

Objective To identify the quality of life (QoL) assessment instruments related to the health of women with fecal incontinence (FI) or anal incontinence (AI).
Data Sources Systematic review conducted in the Virtual Health Library (VHL), PubMed and Cochrane Library databases. The descriptors used were: Questionnaire, Questionnaires, Quality of life, validation, validation Studies, anal incontinence, fecal incontinence and constipation. The search was performed between December 26, 2017 and the beginning of January 2018. The limits used were female gender.
Selection of Studies Initially, 5,143 articles were obtained in the search. The articles of validation for Portuguese of questionnaires for the evaluation of the impact of FI/AI on the QoL of women were considered eligible.
Data Collection The article search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guidelines.
Data Synthesis Of the 5,143 articles, only 2 fulfilled the inclusion and exclusion criteria: Fecal Incontinence Quality of Life (FIQL) and the Wexner scale (WS). The FIQL evaluates the QoL related to FI, not covering flatus incontinence. The WS assesses flatus incontinence and the severity of the AI. The WS obtained an interclass correlation coefficient (ICC) of 0.932 and a Cronbach α coefficient > 0.90. The FIQL obtained intraexaminer and interexaminer reproducibility ranging from 0.929 to 0.957 and from 0.944 to 0.969, respectively.
Conclusions The WS and the FIQL have satisfactory reliability and validity for use during gynecological consultations.
Intralabyrinthine Schwannomas: Disease Presentation, Tumor Management, and Hearing Rehabilitation
Authors: Choudhury Baishakhi , Carlson Matthew , Jethanamest Daniel 
Published: March 2019

AbstractIntralabyrinthine schwannomas (ILS) are rare tumors that frequently cause sensorineural hearing loss. The development and increased use of magnetic resonance imaging in recent years have facilitated the diagnosis of these tumors that present with otherwise nondiscriminant symptoms such as tinnitus, vertigo, and hearing loss. The following is a review of the presentation, pathophysiology, imaging, and treatment with a focused discussion on auditory rehabilitation options of ILS.
Hypothyroidism Increases 90-Day Complications and Cost Following Primary Total Hip Arthroplasty
Authors: Damodar Dhanur , Vakharia Ajit , Zachwieja Erik , Vakharia Rushabh , Hernandez Victor , Roche Martin W. 
Published: March 2019

AbstractHypothyroidism is common, and the incidence has been increasing annually in the United States. Abnormalities in thyroid hormone can have several effects on the endocrine, immune, and musculoskeletal systems of the body. The influence of hypothyroidism on outcomes following primary total hip arthroplasty (THA) is not well reported. The authors hypothesized that hypothyroidism was associated with a higher risk of postoperative complications and 90-day costs following primary THA. A retrospective review from 2005 to 2014 was performed using the Medicare Standard Analytical Files from the Pearl Diver database. Utilizing International Classification of Disease 9th revision (ICD-9) codes, the authors identified patients who underwent THA. Patients with a concurrent diagnosis of hypothyroidism were matched by age, gender, and Charlson's comorbidity index (CCI) to a control group. Ninety-day postoperative complications, readmission rates, complications related to implants, and cost of care were compared and assessed following primary THA between matched cohorts. Statistical analysis was performed using the programming language R (University of Auckland) to calculate odds ratios (OR) along with their respective 95% confidence intervals (95% CI), and p-values. A total of 383,898 patients underwent primary THA. Among them, 191,949 patients were diagnosed with hypothyroidism and 191,949 patients without hypothyroidism. Hypothyroidism was associated with greater odds of postoperative complications (p < 0.001), 90-day readmission rates (p < 0.001), implant related complications (p < 0.001), and total global 90-day episode of care cost (U.S. $17,549.96 vs. $16,645.01; p < 0.001). This study demonstrated an increased risk of postoperative complications (medical or implant related), increased readmission rates, and higher costs among patients with hypothyroidism following primary THA. Surgeons should counsel patients and determine strategies to medically optimize patients to mitigate risk and decrease cost.
Detection of Anti-Cardiolipin and Anti-β2glycoprotein I Antibodies Differs between Platforms without Influence on Association with Clinical Symptoms
Authors: Chayoua Walid , Kelchtermans Hilde , Moore Gary , Gris Jean-Christophe , Musial Jacek , Wahl Denis , Zuily Stéphane , Gianniello Francesca , Fontana Pierre , Remijn Jasper , Urbanus Rolf , de Laat Bas , Devreese Katrien 
Published: March 2019

Background The anti-phospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with persistent presence of anti-phospholipid antibodies (aPL). Laboratory criteria include aPL detection by coagulation tests for lupus anticoagulant (LAC) or solid phase assays measuring anti-β2 glycoprotein I (aβ2GPI) or anti-cardiolipin (aCL) immunoglobulin (Ig) G/IgM antibodies. External quality control programs illustrate that commercially available aPL assays produce variable results.
Objective We aimed to investigate the agreement and diagnostic accuracy of solid phase assays.
Materials and Methods In this multi-centre study, 1,168 patient samples were tested on one site for aCL and aβ2GPI IgG/IgM antibodies by four solid phase test systems. Samples included APS patients, controls and monoclonal antibodies (MoAB) against different epitopes of β2GPI. LAC was determined by the local centre.
Results aCL IgM assays resulted in the most discrepancies (60%), while aCL IgG and aβ2GPI IgM assays resulted in lower discrepancies (36%), suggesting better agreement. Discrepant samples displayed lower median aPL titers. Dependent on the solid phase test system, odds ratios (ORs) for thrombosis and pregnancy morbidity ranged from 1.98 to 2.56 and 3.42 to 4.78, respectively. Three platforms showed lower sensitivity for MoAB directed against the glycine (Gly) 40-arginine (Arg) 43 epitope of domain I of β2GPI.
Conclusion Poor agreement was observed between different commercially available aCL and aβ2GPI IgG/IgM assays, hampering uniformity in the identification of aPL-positive patients. Clinical association was globally concordant between solid phase test systems considering results of the four aPL together. An assay sensitive in detecting the MoAB against Gly40-Arg43 of domain I of β2GPI reached the highest OR for thrombosis.
Neonatal Outcomes Associated with Umbilical Cord Milking in Preterm Multiple Gestations
Authors: Rodriguez Christina E. , Metz Torri D. , Patel Shrena , Abbaszadeh Minda , Yoder Bradley A. , Bardsley Tyler , Clark Erin A. S. 
Published: March 2019

Objective Our aim was to evaluate the effect of umbilical cord milking on outcomes for preterm multiples.
Study Design We implemented a policy of cord milking in neonates born at less than 30 weeks' gestation in September 2011. We compared cord milking in multiples with a historical cohort. Multivariable logistic regression models estimated the effect of cord milking on a composite neonatal adverse outcome. Secondary outcomes were hematocrit at birth, need for blood transfusion, and inotrope use.
Results We identified 149 neonates (120 twins, 29 triplets), 51 historical controls, and 98 neonates with cord milking. Cord milking was associated with a lower rate of adverse composite neonatal outcome in univariable analysis (odds ratio [OR]: 0.36; 95% confidence interval [CI]: 0.15–0.84). However, in multivariable modeling, the effect was not significant (adjusted OR [aOR]: 0.54, 95% CI: 0.23–1.28). Hematocrit was 4.6 unit % (95% CI: 2–7.3) higher in the cord milking group, and cord milking was associated with a lower rate of blood transfusion (aOR: 0.28; 95% CI: 0.1–0.74; p = 0.01). There was no difference in inotrope administration.
Conclusion Umbilical cord milking was not associated with a decrease in composite neonatal adverse outcome. However, we observed an increase in hematocrit and decreased need for blood transfusion in neonates with cord milking.
Single-Step Resection of Sphenoorbital Meningiomas and Orbital Reconstruction Using Customized CAD/CAM Implants
Authors: Goertz Lukas , Stavrinou Pantelis , Stranjalis George , Timmer Marco , Goldbrunner Roland , Krischek Boris 
Published: March 2019

Abstract
Objective Computer-aided design and manufacturing (CAD/CAM) implants are fabricated based on volumetric analysis of computed tomography (CT) scans and are routinely used for the reconstruction of orbital fractures. We present three cases of patients with sphenoorbital meningiomas that underwent tumor resection, orbital decompression, and orbital reconstruction with patient specific porous titanium or acrylic implants in a single procedure.
Methods The extent of bone resection of the sphenoorbital meningiomas was planned in a virtual three-dimensional (3D) environment using preoperative thin-layer CT data. The anatomy of the orbital wall in the resection area was reconstructed by superimposing the contralateral unaffected orbit and by using the information of the neighboring bony structures. The customized implants and a corresponding craniotomy template were designed in the desired size and shape by the manufacturer.
Results All patients presented with a sphenoorbital meningioma and exophthalmos. After osteoclastic craniotomy with the drilling template, orbital decompression was performed. Implant fitting was tight in two cases and could be easily fixated with miniplates and screws. In the third patient, a reoperation was necessary for additional bone resection, as well as drilling and repositioning of the implant. The postoperative CT scans showed an accurate reconstruction of the orbital wall. After surgery, exophthalmos was substantially reduced and a satisfying cosmetic result could be finally achieved in all patients.
Conclusions The concept of preoperative 3D virtual treatment planning and single-step orbital reconstruction with CAD/CAM implants after tumor resection involving the orbit is well feasible and can lead to good cosmetic results.
The Outcomes of Isolated Distal Realignment Procedures in Patellofemoral Instability: A Systematic Review and Meta-analysis
Authors: Tan Si Heng Sharon , Lim Sheng Yang , Wong Keng Lin , Doshi Chintan , Lim Andrew Kean Seng , Hui James Hoipo 
Published: March 2019

AbstractDistal realignment procedures are now commonly performed routinely with proximal realignment procedures. Despite so, only a limited number of publications exist that have looked into the efficacy of isolated distal realignment procedures, and whether there is indeed a need for routine proximal realignment procedures to be added to the distal realignment procedures. The current systematic review and meta-analysis aims to evaluate the outcomes of isolated distal realignment procedures in the management of patellofemoral instability. The review was conducted using the preferred reporting items for systematic reviews and meta-analyses (PRSIMA) guidelines. All studies that reported the outcomes of isolated distal realignment procedures for patellofemoral instability were included. A total of six publications were included, with 347 knees. All studies consistently reported a decrease in the rates of patellofemoral instability or maltracking (odds ratio [OR]: < 0.01; 95% confidence interval [CI]: < 0.01–0.01) and an increase in the odds of having a good outcome (OR: 0.01; 95% CI: < 0.01–0.02) after distal realignment procedures. A total of 24 out of 306 patients (7.8%) had postoperative instability or maltracking, and a total of 220 out of 303 patients (72.6%) were rated to have good or excellent outcomes postoperatively. Isolated distal realignment procedures can lead to good outcomes when used in the management of patellofemoral instability. These include a significantly decreased rate of patellofemoral instability or maltracking and a significantly increased number of patients with excellent or good outcomes postoperatively. Comparisons between patients with and without additional proximal realignment procedures suggest that additional proximal realignment procedures do not definitely improve the outcomes of distal realignment procedures and, therefore, should not be routinely performed in all patients undergoing distal realignment procedures. The Level of Evidence for this study is IV.
Delayed Achievement of Oral Feedings Is Associated with Adverse Neurodevelopmental Outcomes at 18 to 26 Months Follow-up in Preterm Infants
Authors: Lainwala Shabnam , Kosyakova Natalia , Power Kimberly , Hussain Naveed , Moore James E. , Hagadorn James I. , Brownell Elizabeth A. 
Published: March 2019

Abstract
Objective This study aimed to compare neurodevelopmental outcomes in preterm infants at 18 to 26 months corrected age (CA) who did versus did not achieve full oral feedings at 40 weeks postmenstrual age (PMA).
Study Design This retrospective study included infants born between 2010 and 2015 with gestational age <32 weeks and followed between 18 and 26 months CA. Achievement of full oral feedings was defined as oral intake >130 mL/kg/d for >72 hours by 40 weeks PMA. Incidence of cognitive, language, or motor delay, or cerebral palsy at 18 to 26 months CA was compared in multivariable analyses for infants in the two feeding groups.
Results Of 372 included infants, those achieving full oral feedings had lower incidence of any adverse neurodevelopmental outcome (p < 0.001) compared with those who did not achieve full oral feedings. In multivariable analyses, achievement of full oral feedings by 40 weeks PMA was associated with decreased odds of cognitive, language, and motor delays, cerebral palsy, and any adverse neurodevelopmental outcome at follow-up.
Conclusion Achievement of full oral feedings by 40 weeks PMA was associated with better adjusted neurodevelopmental outcomes at 18 to 26 months CA. Inability to fully feed orally at 40 weeks PMA may be a simple, clinically useful marker for risk of adverse neurodevelopmental outcomes.