bluuebunny/crossref_metadata_2025_split huggingface dataset:
One-year test-retest reliability of ten vision tests in Canadian athletes
Authors: Aloosh Mehdi , Leclerc Suzanne , Long Stephanie , Zhong Guowei , Brophy James M. , Schuster Tibor , Steele Russell , Shrier Ian 
Published: July 2019

Background: Vision tests are increasingly being suggested for use in concussion management and baseline testing. Concussions, however, often occur months after baseline testing and reliability studies generally examine intervals limited to days or one week. Therefore, our objective was to determine the one-year test-retest reliability of these tests. Methods: We assessed one-year test-retest reliability of ten vision tests in elite Canadian athletes followed by the Institut National du Sport du Quebec. We included athletes who completed two baseline (preseason) annual evaluations by one clinician within 365±30 days. We excluded athletes with any concussion or vision training in between the annual evaluations or presented with any factor that is believed to affect the tests (e.g. migraines, etc.). Data were collected from clinical charts. We evaluated test-retest reliability using Intraclass Correlation Coefficient (ICC) and 95% limits of agreement (LoA). Results: We examined nine female and seven male athletes with a mean age of 22.7 (SD 4.5) years. Among the vision tests, we observed excellent test-retest reliability in Positive Fusional Vergence at 30cm (ICC=0.93) but this dropped to 0.55 when an outlier was excluded. There was moderate reliability in Negative Fusional Vergence at 30cm (ICC=0.78), Phoria at 30cm (ICC=0.68), Near Point of Convergence break (ICC=0.65) and Saccade (ICC=0.56). The ICC for Positive Fusional Vergence at 3m (ICC=0.56) also decreased to 0.45 after removing one outlier. We found poor reliability in Near Point of Convergence (ICC=0.47), Gross Stereoscopic Acuity (ICC=0.03) and Negative Fusional Vergence at 3m (ICC=0.0). ICC for Phoria at 3m was not appropriate because scores were identical in 14/16 athletes. 95% LoA of the majority of tests were ±40% to ±90%. Conclusions: Four tests had moderate one-year test-retest reliability. The remaining tests had poor reliability. The tests would therefore be useful only if concussion has a moderate-large effect on scores.
Public health research needs for molecular epidemiology and to emphasize homeostasis – could the omnipotent endopeptidase inhibitor α-2-macroglobulin be a meaningful biomarker?
Authors: Schelp Frank Peter , Kraiklang Ratthaphol , Muktabhant Benja , Chupanit Pornpimon , Sanchaisuriya Pattara 
Published: July 2019

Public health authorities in low- and middle-income countries face dramatic challenges in handling rapidly increasing non-communicable diseases (NCDs), due to the epidemiological- and particularly nutritional transition. Among major reasons for the development of NCDs are smoking and alcohol, but overnutrition and obesity are also major threats to population health. Obesity is related to diabetes and cancer, but also has a genetic background. It is difficult to recommend a healthy nutrition. This is because of conflicting nutritional conceptions, and given the complexity of human metabolism understanding this topic can be difficult for the laymen. Public health measures advocating physical activity and refraining from high intake of energy, sugar and soft drinks need to be enhanced by supporting the ‘intrinsic motivation’ to preserve a good health. The mission of public health should be to increase awareness about the complexity of human metabolism, and the involvement of genetic and epigenetics in health and diseases. To maintain homeostasis, means to keep an optimal relationship between catabolism and synthesis, seems to be of particular interest. Preconditions for this is, that public health institutions within the administration- and academic sector follow up developments in life science and molecular biology and conduct population-based research making use of molecular epidemiology, especially those related to key metabolic steps and maintenance of ‘homeostasis’, in balancing catabolism and anabolism. A prospective biomarker for this situation might be α-2-macroglobulin.
Comparison of Gradient Estimation in Cooperative Multi-Agent Source Seeking
Authors: Sahal Mochammad 
Published: July 2019

Agent-based source seeking problem is addressed in this paper. This problem is relevant in, e.g., in hazardous gas leak in a chemical disaster. In the cooperative search, agents develop a formation to effectively search the source by communicating one to another via a communication topology. The source, or the search target, is represented by a scalar field y which might describe a temperature level, hazardous concentration of substances or vapor. Every agent has the information on its own position and the value of y at any instance. The agents are identical modeled as single and double integrator. Consensus filter is used to control the agent formation and comparison three types of gradient estimation are employed to search the source. Experiments show that the proposed schemes give good performance to solve cooperative search for source seeking problem
A Usage of McCall's Software Quality Analysis on the Bonus System of PT Surya Pratama Alam
Authors: Siregar Maria Ulfah , Arif Ahmad Hasan 
Published: July 2019

This research is to analyse the software quality of the Bonus System of PT Surya Pratama Alam Yogyakarta. The goal of this study is to determine the level of users’ satisfaction in the use of the system. Method of analysis used is McCall method which is based on operation products with usability factors. The metrics used are Operability metrics and Training metrics. In the operability metrics, the researchers refer to the J.R. Lewis Questionnaires. Based on the conducted research, researchers can state that the results of software quality measurements of the Bonus System of PT Surya Pratama Alam Yogyakarta is 74.72 % with standard deviation ±14.39 % for Operability metrics and 4.41 seconds with standard deviation ± 1.36 seconds for Training metrics. Based on these two metrics, it can be concluded that the Bonus System of PT Surya Pratama Alam Yogyakarta already has good usability value.
Kiai Fauzan: Pemikiran dan Peranannya di Kabupaten Jepara 1942-1972
Authors: Dalhar M. , Rochwulaningsih Yety , Puguh Dhanang Respati 
Published: July 2019

This study focuses on the life, ideas, and role of Kiai Ahmad Fauzan in developing Islamic teachings and national values. Islam and nationalism are two things that interconnected and not contradictory. In Indonesian history, the two of them caused turmoil, even opposition. The purpose of this study is to prove the return of the Moslem spirit which is in line with the development of local religious leaders, primarily through case studies of local scholars in Jepara, such as Kiai Ahmad Fauzan. This study used a historical method, including heuristics, source criticism, interpretation, and historiography. Kiai Ahmad Fauzan was a leader of the Nahdlatul Ulama (NU) who fought through education and politics to uphold the AhlussunahwalJamaah(Aswaja) ideology in Jepara. Fauzan's Islamic and national ideas can be seen from syair[poems] conveyed to the public. Syairbecame a media for propaganda for Kiai Ahmad Fauzan in spreading the religious understanding of Islam Aswaja. It is delivered to the community as reminder and awareness of harmonious religious and national values. His role in the religious and socio-political fields was seen when Japan began occupying Jepara in 1942. He was the target of arrest because of his role as a cleric. Its leadership formed from religious roles carried out mainly through madrasa and da'wah by traveling from one village to another. Kiai Ahmad Fauzan was involved in socio-religious organizations such as the Indonesian Islamic Assembly (MIAI), Indonesian Muslim Council (Masyumi), and NU, especially during the 1955 elections. Kiai Ahmad Fauzan was also trusted by the government to be the first leader of the Ministry of Religion in Jepara after independence revolution.
Clinical biomarker innovation: when is it worthwhile?
Authors: Kluytmans Anouck , Deinum Jaap , Jenniskens Kevin , van Herwaarden Antonius Eduard , Gloerich Jolein , van Gool Alain J. , van der Wilt Gert Jan , Grutters Janneke P.C. 
Published: July 2019

Abstract

Background
Choosing which biomarker tests to select for further research and development is not only a matter of diagnostic accuracy, but also of the clinical and monetary benefits downstream. Early health economic modeling provides tools to assess the potential effects of biomarker innovation and support decision-making.

Methods
We applied early health economic modeling to the case of diagnosing primary aldosteronism in patients with resistant hypertension. We simulated a cohort of patients using a Markov cohort state-transition model. Using the headroom method, we compared the currently used aldosterone-to-renin ratio to a hypothetical new test with perfect diagnostic properties to determine the headroom based on quality-adjusted life-years (QALYs) and costs, followed by threshold analyses to determine the minimal diagnostic accuracy for a cost-effective product.

Results
Our model indicated that a perfect diagnostic test would yield 0.027 QALYs and increase costs by €43 per patient. At a cost-effectiveness threshold of €20,000 per QALY, the maximum price for this perfect test to be cost-effective is €498 (95% confidence interval [CI]: €275–€808). The value of the perfect test was most strongly influenced by the sensitivity of the current biomarker test. Threshold analysis showed the novel test needs a sensitivity of at least 0.9 and a specificity of at least 0.7 to be cost-effective.

Conclusions
Our model-based approach evaluated the added value of a clinical biomarker innovation, prior to extensive investment in development, clinical studies and implementation. We conclude that early health economic modeling can be a valuable tool when prioritizing biomarker innovations in the laboratory.
Challenges and opportunities for integrating genetic testing into a diagnostic workflow: heritable long QT syndrome as a model
Authors: Lubin Ira M. , Lockhart Edward R. , Frank Julie , See Vincent Y. , Vashist Sudhir , Greene Carol 
Published: July 2019

Abstract

Background
An increasing number of diagnostic evaluations incorporate genetic testing to facilitate accurate and timely diagnoses. The increasing number and complexity of genetic tests continue to pose challenges in deciding when to test, selecting the correct test(s), and using results to inform medical diagnoses, especially for medical professionals lacking genetic expertise. Careful consideration of a diagnostic workflow can be helpful in understanding the appropriate uses of genetic testing within a broader diagnostic workup.

Content
The diagnosis of long QT syndrome (LQTS), a life-threatening cardiac arrhythmia, provides an example for this approach. Electrocardiography is the preferred means for diagnosing LQTS but can be uninformative for some patients due to the variable presentation of the condition. Family history and genetic testing can augment physiological testing to inform a diagnosis and subsequent therapy. Clinical and laboratory professionals informed by peer- reviewed literature and professional recommendations constructed a generalized LQTS diagnostic workflow. This workflow served to explore decisions regarding the use of genetic testing for diagnosing LQTS.

Summary and outlook
Understanding the complexities and approaches to integrating genetic testing into a broader diagnostic evaluation is anticipated to support appropriate test utilization, optimize diagnostic evaluation, and facilitate a multidisciplinary approach essential for achieving accurate and timely diagnoses.
Plasmonic optical tweezers based on nanostructures: fundamentals, advances and prospects
Authors: Kotsifaki Domna G. , Chormaic Síle Nic 
Published: July 2019

Abstract
The ability of metallic nanostructures to confine light at the sub-wavelength scale enables new perspectives and opportunities in the field of nanotechnology. Making use of this unique advantage, nano-optical trapping techniques have been developed to tackle new challenges in a wide range of areas from biology to quantum optics. In this work, starting from basic theories, we present a review of research progress in near-field optical manipulation techniques based on metallic nanostructures, with an emphasis on some of the most promising advances in molecular technology, such as the precise control of single biomolecules. We also provide an overview of possible future research directions of nanomanipulation techniques.
Books in Riga Sent by Martin Ludwig Rhesa to Abraham Jakob Penzel
Authors: Kazakėnaitė Ernesta 
Published: July 2019

Martin Ludwig Rhesa sent Lithuanian books to Abraham Jakob Penzel in Jena twice: in May 1818 and in the spring of 1819. Although this is a well-known fact, there is a lack of knowledge concerning which and how many books were in those two packages. Rhesa himself, in a letter to Scheffner dated April 1819, mentioned the following three books from the second package:Martin Ludwig Rhesa sent Lithuanian books to Abraham Jakob Penzel in Jena twice: in May 1818 and in the spring of 1819. Although this is a well-known fact, there is a lack of knowledge concerning which and how many books were in those two packages. Rhesa himself, in a letter to Scheffner dated April 1819, mentioned the following three books from the second package:1) A new edition of the Lithuanian Bible published by Rhesa (1816);2) Gottfried Ostermeyer’s Erste Littauische Liedergeschichte (1793);3) Gotthard Friedrich Stender’s Neue vollständigere Lettische Grammatik, Nebst einem hinlänglichen Lexico.But it is a mere drop in the ocean, as it is known that Rhesa not only bought books for this occasion, but also added 12 books from his own book collection, and a bundle from Ostermeyer.We also know little about the content of the first package sent to Penzel in May 1819. There are few books in the Latvian Academic Library that have inscriptions with the name Penzel in them. As it is clear from the published copies of the inscriptions (see pictures in this paper), in all of those, Rhesa is mentioned as a sender – all except for one book without any coherent record, which this paper concludes is also one of the books sent by Rhesa. This paper concludes that the following is the list of the books from 1818 (the first three in the list were noticed years ago by Tumelis and Jovaišas):
1) May 29, 1818 Christian Daniel Hassenstein Nuſidawimai βwento Karawimo (1814) (LU AB sign: D6 5813);2) May 31, 1818 Nathaniel Friedrich Ostermeyer Graudenimo balsas (1818) (LU AB sign: D6 5787);3) June 1, 1818 Nathaniel Friedrich Ostermeyer Nedel=Dienos knygeles, krikſʒ́ćʒoniems ſuraβytos (1818), (LU AB sign: D6 5517);4) June 2, 1818 Adam Friedrich Schimmelpfennig Iß naujo pérveiʒdėtos ir pagérintos giesmiû=Knygos (1791), kartu su Danielio Kleino Naujos labbay priwalingos ir Dußoms naudingos Maldû Knygélos (LU AB sign: D6 5515);5) (without a provenance of Penzel himself) Christian Daniel Hassenstein Kaip krikßcʒonißzka Wiera bey Baznycʒia, Ʒmonû pagadinta (1818) (LU AB sign: D6 5518);6) (supposedly) Christian Donaleitis Das Jahr in Vier Gesängen: Ein Ländliches Epos (1818).
Bản chất của mô hình Sinmap và yêu cầu khi áp dụng vào thực tế (Lấy ví dụ ở thung lũng sông Kỳ Cùng - Lạng Sơn)
Authors: Tuân Lê Cảnh , Ngọc Nguyễn Linh , Bào Đặng Văn , Nam Nguyễn Xuân 
Published: July 2019

The nature and requirement of SINMAP model for practical application (example in Ky Cung river valley - Lang Son)
Pre-Truth Life in Post-Truth Times
Authors: Backström Joel 
Published: July 2019

Clearing philosophical ground for diagnoses of the contemporary ‘post-truth’-problematic, this article discusses the systematic and ineliminable ambivalence of claims to truth in public discourse and collective life generally, where truth cannot ultimately be disentangled from untruth. Truth becomes a problem in the relevant sense only where matters are morally-existentially charged, so that acknowledging truth threatens, e.g., loss of self-respect, and self-deception becomes tempting, individually and collectively. To the extent that our life is marked by injustice and destructiveness, it is necessarily also marked by systematic falsification, a conspiracy to deny the truth about it, about us. Collective life exhibits pervasive hostility to interpersonal (moral) understanding, which is repressed through collectively established fake ‘understandings’ and regimes of respectability. The fact/opinion and fact/value distinctions function as defences against understanding, while meaning and truth are seen as things to be determined rather than understood, and the concept of representatability, how things can be made to appear, becomes central. However, standard philosophical views on truth, meaning and morality render the problematic sketched here invisible, because they effectively move – as Wittgenstein arguably realised – wholly within the collective perspective that needs to be problematised.
Keywords: moral understanding, self-deception, collective life, representation, conspiracy theories, political corrrectness
Psikoloji, Mitoloji ve Din
Authors: PATACI Bilal 
Published: July 2019

Mitoloji, psikoloji ve din üçgeninin kesişim
kümesine odaklanarak insan yapısını inceleyen Gülüşan Göcen’in bu eseri, modern
psikolojinin mitosa nasıl yaklaştığı ve din psikolojisinin sahip olduğu yöntem
ve yaklaşımlar çerçevesinde mitosların nasıl ele alınabileceği sorularına yanıt
aramaktadır. Oldukça yoğun ve uzun soluklu bir araştırmanın ürünü olduğu
kolaylıkla farkedilen eserde Göcen; ilk bölümde kitap süresince peşinde olacağı
soruları, konu ve sınırlılıkları izah etmekte, ikinci bölümde ise mitosun ne’liği,
işlevi, yapısı ve özellikleri gibi
başlıklardaki tartışmalara değinerek “mit ve din”, “mit ve psikoloji”
ilişkilerini bütün boyutlarıyla gözler önüne sermektedir. Üçüncü bölümü modern
psikologların mitosları okuma biçimlerine ayıran yazar, son bölümde ise mitosu
daha dar bir perspektiften - din psikolojisinin sınırları dahilinde - ele
almaktadır
Разработка кросскультурного содержания обучения фонетическому аспекту английского языка
Authors: Фатхулина Галия Гализяновна 
Published: July 2019

<p>Статья посвящена актуальной теме обучения иностранному языку не только как средству коммуникации, но и как способу взаимодействия, взаимопонимания и взаимопроникновения различных культур. Теория межкультурной коммуникации как основа современной лингводидактики предполагает усиление межкультурного компонента в содержании предмета «Иностранный язык». Цель статьи — предложить вариант содержания обучения фонетическому аспекту иноязычной речи с учетом межкультурного аспекта.</p>
Дискуссионные вопросы феномена Нового времени в зеркале современности
Authors: Антипов Антон Александрович 
Published: July 2019

<p>Статья посвящена феномену Нового времени и его влиянию на формирование и пути разрешения проблем современного мира. В работе рассмотрены мировоззренческие, психологические и социально-политические истоки модерна и показано, что опосредованное влияние Античности, принципиально новый формат науки-силы и философии деятельного рационального субъекта, социально-политические процессы между государством и обществом, героизм и мещанство в совокупности стали теми ключевыми факторам, которые привели к формированию буржуазной капиталистической эпохи.</p><p>Основными антиномиями, которые рождает нововременной дискурс, являются антиномии о наличии/отсутствии капиталистического духа, ценности рационализма и влиянии глобализации на культуру. Анализ антиномий показал, что утверждение наличия капиталистического духа является умозрительным и необходимо говорить о социально-исторических, политических условиях, которые сформировали определенные поведенческие реакции.</p><p>В заключении подчеркивается, что модерн изменил не сущность человека, а средства и условия человеческого бытия, конструкцию реальности, вытеснил созерцательное и установил потребительское отношение человека к миру, поставив при этом вопрос о будущем культуры и человека в условиях сконструированной им «второй природы».</p>
Implementation of Relating, Experiencing, Applying, Cooperating, Transferring (REACT) Model to Students Learning Achievement in Chemical Basic Law Material at 10th Grade Students of SMA Negeri 1 Kalasan
Authors: Cahyaningrum Ristanti , Febriana Beta Wulan 
Published: July 2019

This study aimed to determine the significant differences of learning achievement at 10th grade students of SMA Negeri 1 Kalasan between the application of conventional learning models with learning models Relating, Experiencing, Applying, Cooperating, Transferring (REACT) in the domain of knowledge, attitudes, and skill on the Basic Chemical Law materials. This study also aimed to know students’ response to learning using REACT model. This research was an experimental using Quasi Experimental Design, namely Posttest Only with Nonequivalent Groups Design. The population in this study was all students of 10th grade SMA 1 Kalasan in the academic year 2017/2018. This study used two classes as the study sample. The data were analyzed using Independent Samples T-Test parametric test for the knowledge and attitude domain, and Mann Whitney U non parametric test for the skill domain. The results of this study can be concluded that (1) there was no significant difference in student learning achievement in the knowledge domain, (2) there was no significant difference in student learning achievement in the attitude domain, and (3) there was significant differences in student learning achievement in the skill domain between the application of conventional learning models with REACT learning models in the Chemical Basic Law and (4) students gave a good response to the REACT learning model performed.
Gambaran Mengenai Metode Mengajar Sesuai dan Tidak Sesuai Dikembangkan dalam Program TK
Authors: Yenny Yenny 
Published: July 2019

<span lang="IN">With the increasing understanding of how young children develop and learn, there has been a greater emphasis on the education of young children. This study aims to obtain a description of appropriate and inappropriate teaching methods developed in a kindergarten program, specifically in the village of South Meruya. This research is qualitative descriptive, using interview method to teaching method of kindergarten teacher. The subjects consisted of 8 kindergarten teachers, consisting of 4 teachers of kindergarten and 4 teachers of kindergarten. The results obtained from this research are the kindergarten teachers in Meruya Selatan Village have shown appropriate teaching methods developed in the kindergarten program almost on all components except the teaching strategy component (addressing the ideas conveyed by the children), content and curriculum approach (aesthetic expression), reciprocal relationship with parents, and program policies (teacher-child ratio). </span>