bluuebunny/crossref_metadata_2025_split huggingface dataset:
PO-186 Effects of Shaolin Ba Duan Jin on Hypertensive Patients
Authors: Hua Xianfeng 
Published: October 2018

Objective To investigate the effects of Shaolin Ba Duan Jin on patients with hypertension.
Methods In the hypertensive patients detected in the national physical fitness test of public officials in Guiyang City, 40 patients with hypertension were selected. The experiment was started after Shaolin Ba Duan Jin has been practiced for seven days and the subjects had learned it.

Experimental method:

Frequency of subjects practicing Ba Duan Jin is 7 days a week, subjects practice once a day, practicing time is 6:00-7:30 am or 18:00 -19:30 pm, practicing lasts 1.5 hours each time (practicing has 3 groups, 14 minutes in each group；subjects rest 2 minutes between groups,；preparing part is 8 minutes；ending part is 5 minutes), record the blood pressure of the subjects before and after each experiment, and fill in the quality of life scale (WHOQOL-BREF scale) regularly for a period of 12 weeks.

Questionnaire method:

Fill in the quality of life scale every three weeks and measure heart rate and blood pressure before and after each exercise.

Mathematical statistics:

The paired sample t test was used to analyze the changes in blood pressure before and after the 12-week experiment.
Results 1) The systolic and diastolic blood pressures of the subjects were significantly lower than before the experiment (P <0.01).
2) The WHOQOL-BREF scale after 12 weeks has improved significantly in all areas than before the experiment.
Conclusions 1) Martial arts Ba Duan Jin has a good influence on the circulatory system of hypertensive patients. The performance is that the heart rate is slow and the systolic and diastolic blood pressures have a downward trend.
2) Martial arts Ba Duan Jin has significant improvement in the physiology, psychology, social relations, environment and other fields .
PO-192 Comparative Study on Screening Results of Functional Movements of Middle-aged and Old Women before and after Square Dance Exercise
Authors: Chen Xiujuan , Tan Jingjing 
Published: October 2018

Objective This study will conduct a functional action screening (FMS) test for middle-aged and older women who participate in square dances, and explore the influence of square dance exercise on the screening results of middle-aged and older women, and provide reference for women's square dance exercise.
Methods Experimental method: A 12-week weekly square dance exercise was conducted on middle-aged and elderly women who participated in the square dance exercise. The functional action screening results of the experimental subjects before and after the experiment were tested and compared.
Results 3.1 Functional screening results of middle-aged and older women before exercise
The average functional screening results of middle-aged and older women before exercise were 13.70±2.518. The shoulder flexibility score of middle-aged and old women was 2.55±0.711, the average score of leg flexibility was 2.55±0.506, and the average score of trunk stability of middle-aged and old women was 1.79±0.485, and the rotational stability was 1.70±0.529. The scores of the front and rear leg squatting modes were 1.58±0.663, the scores of the hurdles were 1.97±0.305, and the scores of the squatting mode were 1.76±0.792.
3.2 Changes in functional action screening results of middle-aged and elderly women after the experiment
After exercise, the squat action mode score was 1.39±1.088, the hurdle step action mode score was 2.30±0.529, the front and rear leg squat action mode was 1.82±0.769, and the shoulder flexibility was 2.36±0.895. The knee lift leg score was 2.36±0.549, the trunk stability score was 1.52±0.870, the rotational stability score was 1.88±0.415, and the total score was 13.67±2.847.
3.3 Comparison of screening results before and after exercise
After the experiment, the total scores of FMS test indicators, shoulder flexibility, trunk stability, rotational stability, squat movement mode and front and rear leg squat mode were not significantly changed (P = 0.951, 0.311, 0.119, 0.056, 0.070 and 0.118 respectively).
The hurdle step movement mode was significantly improved, and the mean increased from 1.97 to 2.30 points (p<0.01).
Conclusions 4.1 The functional quality of middle-aged and older women who participate in square dance exercises is generally not high.
4.2 Once a week, 2 hours of 12-week square dance exercise can effectively improve the walking movement mode of middle-aged and older women.
4.3 Once a week, 2 hours of 12-week square dance exercise can not effectively improve the upper and lower limb flexibility, core stability and squat and front and rear leg movement modes of middle-aged and older women.
4.4 Middle-aged and older women who participate in square dance exercise need to add functional training in a targeted manner, instead of relying solely on square dance.
PO-196 The Change of Biochemical Indicators of Urine of Young soccer Athletes after Match
Authors: Yang Yanan , Song Yan , Wang Lu 
Published: October 2018

Objective It is an important content in scientific training that Scientific and effective assessment of athletes' physical function changes. By analyzing the changes of several urine biochemical indexes after the athletes' competition, the physical function and recovery of the athletes are timely understood and the basis of scientific training is provided for the coaches.
Methods Urine biochemical indexes after 5 warm-up matches of 10 first athletes were measured with ten portable urine test instruments, including nitrite (NIT), acid alkalinity (pH), urine sugar (GLU), urine protein (PRO), urinary occult blood (BLD), urinary ketone body (KET), urinary bilirubin (BIL), urinary bilirubin (URO), urine specific gravity (SG), white blood cell (WBC). And statistics the positive rate.
Results The urine protein and urine bilirubin were found in different degrees after the competition. The urine protein of the backfielder and the back waist was (+ + +) or (+ +). Some of the next day morning recovered normal or weak positive, the urine protein of a few athletes was (+); some of the players' Urine Bilirubin (+), the few accompanied by urinary occult blood, the positive rate was low, most of them were low. The morning urine of a number of athletes returned to normal.After the competition, the urine specific gravity of athletes was more than 1.030, and no change was observed in the morning. Other indicators did not change significantly after the match and the following morning.
Conclusions Changes in urine biochemical indicators reflect the athletes' body by the competition load stimulation, in which urine protein and urine bilirubin are more sensitive to exercise load. The difference of the change degree of urine biochemical indexes in different position athletes suggests the individual differences of athletes, and also suggests the development trend of the competition, which is in line with the competitive level of the other players.
PO-103 The mechanism of long-term regular exercise intervention on liver injury in patients with NAFLD based on miR-146a regulation of TLR4/NF-KB signaling pathway
Authors: Peng Qi , Chen Jiaqin , Chen Wei , Shao Chang Feng , Yuan Afang 
Published: October 2018

Objective To investigate the effects of long-term regular exercise on hepatic function in patients with non-alcoholic fatty liver (NAFLD) using blood biochemistry and liver fibrosis markers, and to compare the differential expression of cytokines related to TLR4/NF-KB signaling pathway. A preliminary discussion was made on its regulation mechanism.
Methods Forty patients with NAFLD diagnosed in the Hunan Normal University School of Medicine, according to the degree of steatosis and exercise intervention, the patients were divided into control group (NAFLD group) 20 cases and long-term regular exercise group 20 cases, and the same time in our hospital Twenty patients with physical examination were normal controls; general data of all subjects, ALT, AST, GGT, serum type III procollagen (PCIII), hyaluronan (HA), and type IV collagen (CIV) were examined; Fluorescent quantitative PCR was used to detect the differential expression of TLR4/NF-KB signaling pathway-related cytokines and miR-146a in the blood of each group of subjects, revealing the effects and possible mechanisms of long-term regular exercise on liver fibrosis.
Results Compared with the normal group, the levels of serum ALT, AST, GGT, PCIII, HA, and CIV in the non-alcoholic fatty liver patients were significantly lower in the long-term regular exercise group than in the control group; blood TLR4, NF-KB, MY-D88 Compared with the control group, the gene expression level was significantly downregulated in the long-term regular exercise group.
Conclusions Long-term regular exercise can effectively reduce nonalcoholic inflammatory liver injury and has a clear anti-fibrotic effect. Its mechanism may be related to long-term regular exercise through regulating the TLR4/NF-KB signaling pathway related factors and the regulation of molecular miR-146a, reducing inflammation and preventing the formation of fibrosis.
PO-105 Exercise regulates HMGB1 / TLR4 / NF- κ B pathway by H2S to improve OJ intestinal injury
Authors: Shao Changfeng , Chen Jiaqin , Chen Wei , Peng Qi , Li Di , Yuan Afang 
Published: October 2018

Objective To study the effect of aerobic exercise on the damage of intestinal mucosal barrier function caused by obstructive jaundice（OJ）and to explore its mechanism of action.
Methods 50 male KM mice were randomly divided into 5 groups: sham operation group (S), model group (M), exercise group (TM), DL-Propargylglycine + exercise (PT) group and sodium hydrosulfide + exercise (NT) group.In addition to the S group which are in the common bile duct to the abdominal wall hanging 48 hours to build mouse obstructive jaundice model. In the PT group, PAG (40 mg/kg) was intraperitoneally injected 7 days after surgery; NaHS (50 μmol/kg) was intraperitoneally injected in the NT group 7 days after surgery; TM group, NT group and PT group were graded at 0%, and the speed was 10m/min no weight training (30min/day).After 6 weeks, HE staining was used to observe the morphological changes of the intestinal mucosa.Biochemical analysis was used to detect the concentration of hydrogen sulfide (H2S) in blood and ileum, and total bilirubin (TBIL), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) Liver function, diamine oxidase (DAO), D-lactic acid intestinal barrier function biochemical index; qRT-PCR and immunohistochemical staining were used to observe the expression changes of H2S-mediated related channel mRNA and protein（HMGB1, TLR4 and NF-Kbp6）in intestinal tissues.
Results HE staining showed that the intestinal mucosa of group M was atrophied and the villus was broken.Compared with M group, the intestinal mucosa arrangement in TM group was relatively regular. Compared with TM group, intestinal mucosa atrophy in PT group, fluff hair loss, sparseness and disorder, partial mucosa The layer was separated from the lamina propria and the gland was severely damaged. The intestinal mucosa of the NT group was relatively regular, and the changes of intestinal mucosa atrophy were restored. Serum test results showed that H2S levels were higher in the TM group than in the M group; compared with the TM group, the PT group decreased and the NT group increased. DAO level: The TM group was lower than the M group; compared with the TM group, the PT group was elevated and the NT group was decreased. Changes in serum D-lactic acid levels were similar to DAO. The results of qRT-PCR and immunohistochemical staining showed that the expressions of HMGB1, TLR4 and NF-Kbp6 mRNA and protein in the intestinal tissues of mice in TM group were significantly lower than those in M group and PT group, and the mRNA and protein expression levels in NT group were the lowest.
Conclusions Aerobic exercise inhibits the HMGB1 / TLR4 / NF-κB signaling pathway through the H2S / CSE system, thereby exerting a protective effect on the intestinal mucosal barrier.
PO-113 Long-term Various Load Training Effects on Free Radical Metabolism in the Brain of Aging Mice
Authors: Wei Cuilan , Li Xue 
Published: October 2018

Objective To investigate the effects of long-term various load aerobic exercise on the free radical metabolism of the brain in aging mice through the establishment of different swimming exercise models.
Methods sixty 3-month-old male Kunming mice were randomly and equally divided into five groups, which were the control group (group C), 10 minute exercise group (group E1), 30 minute exercise group (group E2), 60 minute exercise group (group E3), and 90 minute exercise group (group E4). Group C had regular feeding during the natural aging time in 8 months without any exercise intervention. All other exercise groups performed different load swimming exercise (from 10 to 90 minutes as mentioned above) during the same 8 month period. All subjects were decapitated after exercise on the last day of the 8th month; and the brain tissues were harvested as samples. The malondialdehyde (MDA) amount was measured by the Thiobarbituric Acid method, and the superoxide dismutase (SOD) activity level was measured with Xanthine Oxidase method.
Results group E3 demonstrated significantly higher SOD activity level and lower MDA amount than the other groups.
Conclusions Long-term, medium-load aerobic exercise had greatly impacted the metabolism of free radicals in the brain of the mouse, evidenced by increased SOD activity level and decreased MDA production. These effects may indicate that this exercise model may be beneficial in slowing down brain aging by eliminating free radicals and improving brain anti-oxidation ability.
PO-115 Effects of Phosphatidylserine on Mental States in Elite Shooters
Authors: Lu Jiaojiao , An Yan 
Published: October 2018

Objective The purpose of this study was to examine effects of a short-term oral supplementation of PS on biochemical stress indicators, whole brain neurotransmitters, mood states, and sleep quality in elite shooters.
Methods Eighteen shooters including 9 males and 9 females participated in the study. They were randomly assigned into either of the three groups: 1) those who ingested PS at 400 mg∙day-1 (n=6) (PS-400); 2) those who ingested PS at 800 mg∙day-1 (n=6) (PS-800); 3) those who with no supplement (n=6) (CON). PS supplementation lasted for 14 days and was administered in a double-blinded fashion. Within a week prior to the supplementation, serial venous blood samples were taken for measuring serum levels testosterone (T), cortisol (C), blood urea nitrogen (BUN), and creatine kinase (CK). Subjects also completed the Profile of Mood States (POMS) scale and the Pittsburgh Sleep Quality Index (PSQI) questionnaire and undertook electroencephalogram that determined activation values of six neurotransmitters in whole brain, including inhibition of medium (INH), five hydroxy-tryptamine (5-HT), acetylcholine (ACH), dopamine (DA), norepinephrine (NE), and excited medium (EXC). Subjects repeated the same testing protocols and all variables were measured again after 14 days of supplementation.
Results No between-group differences in all variables were observed at the baseline prior to the start of supplementation. After supplementation, both C and C increase were lower (P=0.025, P=0.016, respectively) in PS 800 than CON, while no significant differences in C and C increase were seen between PS-400 and CON and between PS-800 and PS-400. 5-HT and DA were higher (P=0.049, P=0.019, respectively) in PS-800 than CON, while no differences in 5-HT and DA were observed between PS-400 and CON and between PS-800 and PS-400. All neurotransmitters were increased by supplementation in PS-800, with ACH and DA reaching statistical significance (P=0.050,P=0.029, respectively). A synchronized trend of INH, 5-HT, ACH, DA，NE, and EXC were observed in a few brain regions (P<0.05). PS Supplementation decreased panic score of POMS following both PS-400 and PS-800, with a greater decrease seen in PS-800. The panic score post-supplementation was lower in PS-800 than PS-400 (P=0.016) or CON (P=0.027). Although results of PSQI indicated an improved sleep quality following supplementation in both PS-400 and PS-800, these improvements did not reach statistical significance and no differences in PSQI were seen across the three groups.
Conclusions It appears that supplementation with phosphatidylserine at 800 mg∙day-1 for 14 days can reduce stress hormones, modulate central neurotransmitters, and mitigate negative emotions, thereby alleviating stress levels among elite shooters.
PO-229 Physiology of Aerobic Exercise in Atherosclerosis
Authors: Xie Jinfeng 
Published: October 2018

Objective -
Methods -
Results -
Conclusions Clinicians has always been excessively reliant on drugs to treat patients with Atherosclerosis.Resently, it is advocated to do aerobic exercise. Such knowledge should aid in preventing and treating dyslipidemia, oxidative stress,inflammation, vascular endothelial dysfunction while reducing the risks of atherosclerosis.
PO-232 The Regulation of Vimentin in Skeletal Muscle Fibrosis Affected by High-load Exercise
Authors: Liu Xiaoran 
Published: October 2018

Objective Long-term movement could induce micro-damage of skeletal muscle, increase collagen significantly, and appear skeletal muscle fibrosis. Vimentin is one of the most important proteins in evaluating the fibrosis after muscle injury. TGF-β1 could up-regulate Vimentin expression, promoting cell migration and accelerating fibrosis and injury repair. This study mainly explored the role of TGF-β1/Vim in skeletal muscle fibrosis affected by a bout of high-load exercise. And we tried to find whether the expression of vimentin could regulate the regeneration of muscle fiber and the remodeling of connective tissue.
Methods SD rats were divided into 7groups: control group, immediately, 6-hour, 12-hour, 24-hour, 48-hour and 72-hour after group. Western Blot was used to detect TGF-β1, vimentin, RhoA, ROCK1 and CTGF(connective tissue growth factor) expressions. Electron microscopy was used to observe the changes of collagen in skeletal muscle.
Results Vimentin protein exprsssion increased quickly at 6-hour after exerciese. At 48-hour, the vimentin expression reached the peak. And then the expression of vimentin gradually decreased.
The expressions of TGF-β1, RhoA, ROCK1 and CTGF gradually increased after exercise. The peak of these expressions appeared at 12-hour respectively. Then these protein expressions declined slowly. Collagen in skeletal muscle became long and thick in 48-hour and 72-hour after exercise.
Conclusions A bout of high-load exercise could induce skeletal muscle fibrosis. RhoA-ROCK1 maybe affect TGF-β1/Vim expressions as main regulators, and then the protein expression vimentin could regulate the regeneration of muscle fiber and the remodeling of connective tissue as an important evaluation factor.
PO-233 The Neuroprotective Effects of Aerobic Exercise and Oral Resveratrol on Hippocampal Neurons in Diabetic Rats
Authors: Li Han 
Published: October 2018

Objective The purpose of this study is to explore the effects of aerobic exercise combined with oral resveratrol on ethology and BDNF and CREB proteins of hippocampus neurons in diabetic rats, in order to provide a theoretical basis for revealing the neuroprotective mechanism of exercise and resveratrol.
Methods 45 male Sprague Dawley rats, aged 8 weeks, were randomly divided into 5 groups: normal control (NC), diabetes control (DC), diabetes exercise (DE), diabetes resveratrol (DR) and diabetes exercise and resveratrol (DER). Exercise-related groups performed 8-week swimming training (60min/d，5d/week). Morris maze test, 7d. Escape latency time, strategy of finding platform performance, the protein expression of BDNF and CREB from hippocampus neurons were measured.
Results 1）Compared with DM, DR and RE groups, the escape latency of DRE group was significantly shortened (p<0.01), and the strategy of finding platform performance was remarkably improved (p<0.05). 2) Compared with NC group, the protein expression of BDNF of DM group was obviously decreased (p <0.01), while in DRE group was improved significantly than that in DE group (p< 0.05). 3) The level of CREB expression in DM group clearly lower than in group NC (p<0.01), and the expression of CREB in DER and DE groups were remarkably increased (P <0.01) .
Conclusions Eight weeks of swimming training and/or oral resveratrol could increase the expression level of BDNF and CREB protein in the hippocampal neurons of diabetic rats, and improve the ability of spatial learning from behavioral study. It is suggested that the aerobic exercise training and the SIRT1 mechanism of resveratrol perhaps improve the situation of high glucose and indirectly stimulate the expression of BDNF and CREB protein. As a result, that leads to improve the impair of learning and memory which caused by diabetes.
PO-244 The Differences of 18~60 Years Old Adults’ Basal Metabolism depend on Their BMI in Nanjing
Authors: Ai Lei 
Published: October 2018

Objective By comparing the differences of adults’ basic metabolic values depend on their BMI, we try to make clear the relationship between different somatotype and human daily total energy expenditure(EE) because basic metabolism accounts for the 60~70% of the EE. Then we can provide a reference including reasonable energy intake and suitable physical activity load for adults of different somatotype.
Methods A self-made health questionnaire was used to select these who are aged of 18~60 years old with no bad hobby and no bad habits (women were not in the period of menstruation), we totally recruited 181 volunteers of which 81 were normal somatotype(18.5≤BMI＜24, 33 Male 39.76±12.23 years old, BMI21.90±1.40 vs Female 39.69±13.05 years old, BMI21.38±1.40) and 72 were overweight somatotype (24≤BMI＜28, 49 Male 40±13.38 years old, BMI25.26±1.15 vs Female 40.61±10.72 years old, BMI25.53±1.09) and 28 were obese somatotype (28≤BMI, 18 Male 39.33±14.23 years old, BMI30.14±2.22 vs female 41±12.10 years old, BMI29.36± 1.25), and the basic metabolic value was measured by respiratory chamber.
Results The basal metabolic values of male and female aged of 18~60 years old in Nanjing were 2077.10±262.12Kcal and 1682.87±203.69Kcal respectively. The basic metabolic values of male and female with normal BMI are 2046.41±242.73Kcal and 1628.65±184.28kcal respectively. The basic metabolic values of male and female with overweight BMI are 2061.10±232.90Kcal and 1741.10±220.14Kcal respectively. The basal metabolic values of male and female with obese BMI are 2176.92±350.64Kcal and 1809.20±175.82Kcal. The basic metabolic values of adults with different sex but in the same BMI all reached a statistically significant difference (P≤0.01). To those adults with same sex but in different BMI, the basic metabolic values between normal BMI and overweight BMI or obese BMI all reached a statistically significant difference for female (P≤0.05), but there were no statistically significant difference for male (P > 0.05).
Conclusions For 18~60 years old adults, it is important to actively control their weight if they find their BMI are overweight, especially for women, because women are significantly more easy to return to normal BMI compare with men, but the advantages depend on different sex will disappeared if they keep on develop into obese BMI.