bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison between use of combination of mifepristone and misoprostol versus misoprostol alone in the management of intrauterine fetal death
Authors: Talasani Sreeveena , Venkamolla Pran Hitha , Betha Kalpana 
Published: June 2018

Background: Intrauterine fetal death (IUFD) is estimated to occur in 1% of all pregnancies. The advent of prostaglandins has revolutionized the management of IUFD. There are limited studies using a combined regimen of mifepristone and misoprost for induction of labor in IUFD. Hence this study was undertaken to assess the efficacy and safety of combined regimen with misoprostol alone, in the management of IUFD.Methods: This hospital based prospective study included 60 pregnant women with IUFD admitted at Mediciti Institute of Medical Sciences, during the period January 2015 to July 2016. An ultrasound scan was performed to confirm IUFD and localize the placenta. Women were divided alternatively into 2 groups with 30 in each group (group 1- women received 200 mg mifepristone orally followed by misoprostol after 24 hours & in group 2, 100 µg misoprostol every 6 hourly for a maximum of 4 doses between gestational age 24-26 weeks, 25-50 µg 4 hourly for a maximum of 6 doses beyond 26 weeks).Results: The mean induction to delivery interval was 10 hours in group 1 and 16.3 hours in group 2 (p value 0.007). Mean dose of misoprostol required in group 1 was 1.87 and 2.67 in group 2 (p value 0.008). With respect to side effects, the two groups did not differ significantly.Conclusions: The combined regimen was more effective than misoprostol for the induction of labour in IUFD, in terms of higher rate of successful delivery and shorter induction to delivery interval.
Analise dos benefícios da cinesioterapia laboral a curto, médio e longo prazo: uma revisão de literatura
Authors: Iackstet Leandro , Gonçalves Ana Carolina Barbosa Faria , Soares Silvia Fiorillo Cabrera 
Published: June 2018

A revolução industrial trouxe o desenvolvimento e o capitalismo para a humanidade, a busca pelo lucro promoveu o aumento na jornada de trabalho e consigo as lesões e doenças relacionadas ao trabalho. A falta de organização associada ao grande esforço do trabalhador ocasionou o cansaço físico e mental o que o tornou suscetível a desenvolver LER/DORT. Devido a isso, o fisioterapeuta atua nas empresas aplicando a cinesioterapia laboral para prevenir e minimizar tais problemas de saúde e promover o bem estar, saúde e produtividade para a empresa. Dentro deste contexto este estudo tem como objetivo realizar uma revisão de literatura a fim de verificar os benefícios da cinesioterapia laboral a curto, médio e longo prazo, e verificar se a implantação de um projeto de cinesioterapia laboral promove melhora nas condições de trabalho, bem como a redução da fadiga no trabalho e aumenta da eficácia e produtividade. Como metodologia foi realizada uma revisão de literatura, com pesquisa em bases de dados e os artigos selecionados foram analisados. Como resultados, verificou-se que a prática da cinesioterapia laboral traz benefícios ao trabalhador verificados em curto prazo (à partir de um mês de implantação), melhorando a saúde e a qualidade de vida dos trabalhadores, promovendo impacto positivo no seu dia a dia e em sua jornada de trabalho, além de contribuir para a empresa no sentido de maior eficácia no trabalho e redução do absenteísmo e afastamentos médicos.Descritores: Técnicas de Exercício e de Movimento; Exposição Ocupacional; Ergonomia; Revisão.
Implante imediato associado à infecção periapical crônica: relato de caso clinico
Authors: Mattos Thiago Borges , Mendes Felipe Campos , Suzuki Thaís Yumi Umeda , Gulinelli Jéssica Lemos , Galito Paola Ferreira , Santos Pâmela Leticia 
Published: June 2018

A busca por novas técnicas cirúrgicas preservando a integridade dos tecidos periodontais associado à reabilitação com implantes dentários favorece a qualidade estética e funcional, garantindo assim a satisfação dos pacientes. O objetivo do trabalho foi demonstrar a reabilitação com implante imediato em alvéolo com infecção associado a provisionalização imediata e proservação de 36 meses após a reabilitação final. Paciente apresentou-se com elemento 24 com mobilidade grau III, defeitos ósseos ao redor do dente, drenagem purulenta e bolsa profunda à sondagem de (>7 mm). Foi utilizado o protocolo de regeneração óssea guiada (ROG) com o substituto ósseo para preenchimento do “gap” entre o implante e o osso alveolar, com o uso de tela de titânio para ganho ósseo vertical e horizontal e membranas autólogas de fibrina obtidas através do processo de centrifugação e preparo. Após o período de osseointegração, foram realizados procedimentos de moldagem personalizada para a reabilitação final com prótese metalocerâmica. No período de 36 meses de acompanhamento clínico e radiográfico não há sintomatologia dolorosa, infecção, mobilidade do implante e perda óssea peri-implantar acentuada. O paciente apresentou-se satisfeito com relação à estética e função protética.Descritores: Infecção; Implantes Dentários; Reabilitação Oral.
Formation of Regular Domain Structures in Quenched Ferroelectrics Under the Influence of an External High-frequency Electric Field
Authors: Stefanovich L.I. , Mazur O.Y. , Sobolev V.V. 
Published: June 2018

Introduction:
Within the framework of the phenomenological theory of phase transitions of
the second kind of Ginzburg-Landau, the kinetics of ordering of a rapidly quenched highly nonequilibrium
domain structure is considered using the lithium tantalate and lithium niobate crystals as an example.

Experimental:
Using the statistical approach, evolution equations describing the formation of the domain
structure under the influence of a high-frequency alternating electric field in the form of a standing
wave were obtained. Numerical analysis has shown the possibility of forming thermodynamically
stable mono- and polydomain structures. It turned out that the process of relaxation of the system to
the state of thermodynamic equilibrium can proceed directly or with the formation of intermediate
quasi-stationary polydomain asymmetric phases.

Results:
It is shown that the formation of Regular Domain Structures (RDS) is of a threshold character
and occurs under the influence of an alternating electric field with an amplitude less than the critical
value, whose value depends on the field frequency. The conditions for the formation of RDSs with a
micrometer spatial scale were determined.

Conclusion:
As shown by numerical studies, the RDSs obtained retain their stability, i.e. do not disappear
even after turning off the external electric field. Qualitative analysis using lithium niobate crystals
as an example has shown the possibility of RDSs formation in high-frequency fields with small amplitude
under resonance conditions
Heat and Mass Transfer Characteristics of Nanofluids in a Rotating System: A Convective Boundary Layer Flow
Authors: Parvathi M. , Leelaratnam A. , Raju M.C. 
Published: June 2018

Introduction:
Convective heat and mass transfer in nanofluids is a topic of major contemporary
interest in both science and technology. In view of this, an unsteady MHD free convective flow of
nanofluids through a porous medium bound by a moving vertical semi-infinite permeable flat plate with
a constant heat source and convective boundary condition in a rotating frame of reference is studied
theoretically.

Experimental:
The novelty is the consideration of constant heat source and convective boundary condition
in a rotating frame. The velocity along the plate i.e., slip velocity is assumed to oscillate in time
with constant frequency so that the solutions of the boundary layer are of the same oscillatory type. The
dimensionless governing equations for this investigation are solved analytically using small perturbation
approximation. Two types of nanofluids, namely Cu-water and Al2O3-water are used.

Results:
The effects of various parameters on the flow, heat and mass transfer characteristics are discussed
through graphs and tables.

Conclusion:
An increase in the convective parameter and nanoparticle volume fraction leads to increase
the thermal boundary layer thickness but opposite effect occurs for heat generation.
[INCISO]
Authors: Aspillaga Carina 
Published: June 2018

La sección [INCISO] sólo tiene numeración interna y no es indexada. Recoge manifestaciones artísticas de la región de Valparaíso, Chile, expuestas en el formato de la revista Panambí, tales como fotografías, dibujos, manifiestos, escritos experimentales, partituras o expresiones similares. Una de estas imágenes se incluye en la portada de la revista, distribuyéndose las demás a lo largo de las páginas interiores, en diálogo con las demás contribuciones. La publicación en [INCISO] se realiza por invitación expresa de los editores. No obstante, los interesados pueden escribirnos para eventualmente publicar sus trabajos. Para ello, se requiere únicamente indicar nombre, afiliación institucional, organizacional u ocupación del autor y correo electrónico. Se entiende que la contribución es objeto de una construcción artística desde su comienzo.En Panambí n. 6, la invitada es Carina Aspillaga, actriz y directora teatral, quien nos presenta [Teatro La Washa: Caótica / MaríaClara].
Intellectual Property Rights, Innovation and Healthcare: Unanswered questions in Theory and Policy
Authors: Srinivas Smita 
Published: June 2018

Intellectual property regimes are usually presumed to exert positiveinducements on technological innovation. However, given the dire nature ofaccess to critical health technologies for most of the world’s population, it isworth revisiting this assumption for health technologies. This paper situatesintellectual property rights (IPRs) for health technologies at the intersectionof three fields: innovation studies, welfare theories, and international politicaleconomy. It revisits the conceptual underpinnings of property rights with particularrelevance for needs of today’s industrializing, or so-called “developing”countries. This paper argues that the debates on IPR have poorly exploredcounterfactuals in pharmaceuticals and biotechnologies where other meansof inducement may exist and innovations may arise in conditions where IPR iseither absent or irrelevant. To do this, it first discusses utility as a basis for IPRsand the challenges –philosophical, theoretical and most importantly, practical- intranslating this to real-world use. It draws on history to analyze pharmaceuticalprior drug generations and alternate inducements. The article offers a novelconceptual framework to study innovation in developing contexts where IPR can be specifically situated. If the real goal is accessible and affordable healthcare- anissue of immense importance worldwide- then we may need to cease barking upthe wrong tree of intellectual property rights.
Taxa de Juros e Regime de Metas de Inflação: Uma Análise Empírica para a Economia Brasileira
Authors: Oliveira Luma De , Abrita Mateus Boldrine 
Published: June 2018

Este artigo tem como principal objetivo verificar como variáveis macroeconômicas selecionadas respondem a choques na taxa de juros básica da economia brasileira, com o propósito de verificar a eficácia do Regime de Metas de Inflação. Ou seja, analisar variáveis, como a taxa de desemprego, a produção industrial, o índice de credibilidade e a taxa de inflação, respondem a mudanças no principal instrumento de política monetária e quais os custos socioeconômicos alcançados por estas mudanças. Portanto, foi desenvolvido um modelo de Vetores Autoregressivos para a economia brasileira no período de janeiro de 2002 a outubro de 2013 e, assim, analisadas as principais ferramentas provenientes deste modelo. Os principais resultados alcançados foram que: existe uma grande defasagem entre mudanças na taxa de juros e a resposta da taxa de inflação; a variação em relação à taxa de desemprego a mudanças nos juros é mínima; e, a produção industrial é altamente prejudicada por alterações na taxa de juros.
OPTIMIZATION OF GOODS DISTRIBUTION ROUTE ASSISTED BY GOOGLE MAP WITH CHEAPEST INSERTION HEURISTIC ALGORITHM (CIH)
Authors: Hignasari L. Virginayoga , Mahira Eka Diana 
Published: June 2018

In the distribution of goods, the efficiency of goods delivery one of which was determined by the path that passed to deliver the goods. The problem of choosing the shortest route was known as the Traveling Salesman Problem (TSP). To solve the problem of choosing the shortest route in the distribution of goods, the algorithm to be used was Cheapest Insertion Heuristic (CIH). This study aims to determine the minimum distance traveled by using the CIH algorithm. Researchers determine the route and distance of each place visited by using google map. The concept in the CIH algorithm was to insert an unexpired city with an additional minimum distance until all cities are passed to get the solution of the problem. The step completion problem with CIH algorithm was: 1) search, 2) making sub tour; 3) change the direction of the relationship, 4) repeat the steps so that all places are included in the sub tour. Theoretically, the total distance calculated using the CIH algorithm is 20.2 km, while the total distance calculated previously traveled with the ordered route is 25.2 km. There was a difference of 5 km with the application of CIH algorithm. The difference between the distance certainly has an impact on the optimal distribution of goods to the destination. Therefore, CIH algorithm application can provide a solution for determining the shortest route from the distribution of goods delivery.
Influence of Thermal Stress on Simulated Localized and Generalized Wear of Nanofilled Resin Composites
Authors: Tsujimoto A , Barkmeier WW , Takamizawa T , Latta MA , Miyazaki M 
Published: June 2018

SUMMARY

Objective:
This study investigated the influence of thermal stress on the simulated localized and generalized wear of nanofilled resin composites.

Methods:
Six nanofilled resin composites were evaluated and then subjected to a wear challenge of 400,000 cycles in a Leinfelder-Suzuki (Alabama) wear simulation device after 24 hours of water storage (24-hour group) and 24 hours of water storage and 10,000 thermal cycles (TC group). Simulated localized wear was generated using a stainless-steel ball bearing, and simulated generalized wear was generated using a flat-ended stainless-steel cylinder. Wear testing was accomplished in a water slurry of polymethyl methacrylate beads. Simulated localized and generalized wear was determined using a noncontact profilometer (Proscan 2100) in conjunction with Proscan and AnSur 3D software.

Results:
Wear was significantly different (p&lt;0.05) among the resin composites for both simulated localized and generalized wear of either the 24-hour group or the TC group. The simulated localized wear of the TC group was significantly greater than that of the 24-hour group; however, the simulated generalized wear of most of the resin composites of the TC group was not significantly different from that of the 24-hour group.

Conclusion:
The simulated localized and generalized wear of nanofilled resin composites is material dependent. The simulated localized wear of nanofilled resin composites appears to be influenced by thermal stress, whereas this effect is not as apparent in simulated generalized wear testing.
Rickets: Historical, Epidemiological, Pathophysiological, and Pathological Perspectives
Authors: Walker Alfredo , el Demellawy Dina , Davila Jorge 
Published: June 2018

Rickets was a common metabolic disease of bone a century ago in Europe, North America, and East Asia (mainly due to vitamin D deficiency) but was largely eradicated in growing children by use of cod liver oil and the introduction of vitamin D fortification of milk in the 1930s in the United States. Vitamin D deficiency (VDD) remains the most common form of metabolic bone disease that is entirely preventable and treatable. Historically, rickets has appeared in sporadic epidemics and, despite the introduction of numerous preventive strategies, VDD has remained a global health problem amongst children. Moreover, developed countries such as Canada, Australia, the United Kingdom, and the United States have not been exempt from this. The radiological and histological features of rickets are both distinctive and characteristic and they reflect the underlying pathophysiological issue of decreased mineralization of bone as a result of VDD. The radiological features include 1) metaphyseal cupping and fraying, 2) poor mineralization of epiphyseal centers, 3) irregular and widened epiphyseal plates, 4) increased distance between the end of shaft and epiphyseal center, 5) cortical spurs at right angles to the metaphysis, 6) coarse trabeculation, and 7) periosteal reactions. Fractures may also be evident. The histological features of rickets reflect the failure of cartilage to mineralize and undergo resorption. This results in 1) disordered proliferation of chondrocytes in the hypertrophic zone secondary to a lack of apoptosis, 2) loss of the columnar arrangement of chondrocytes that results in thickening and disorganization of the hypertrophic zone, 3) tongue-like projections of cartilage that extend into the spongiosa, 4) irregularity of the limit between the proliferative and hypertrophic zones, and 5) penetration of blood vessels into the hypertrophic zone. The case of a premature 3-month-old female infant, born in the winter months in the arctic region of Canada who died from a lobar pneumonia with an incidental finding of radiological and pathological evidence of rickets, is presented. The case is used to review the entity of rickets from historical, pathophysiological, radiological, and histological perspectives.
Analysis of the Medical Assistance in Dying Cases in Ontario: Understanding the Patient Demographics of Case Uptake in Ontario since the Royal Assent and Amendments of Bill C-14 in Canada
Authors: Rosso Alexandra E. , Huyer Dirk , Walker Alfredo 
Published: June 2018

On June 17, 2016, the Canadian government legalized medical assistance in dying (MAID) across the country by giving Royal Assent to Bill C-14. This Act made amendments to the Criminal Code and other Acts relating to MAID, allowing physicians and nurse practitioners to offer clinician-administered and self-administered MAID in conjunction with pharmacists being able to dispense the necessary medications. The eligibility criteria for MAID indicates that the individual 1) must be a recipient of publicly funded health services in Canada, 2) be at least 18 years of age, 3) be capable of health-related decision-making, and 4) has a grievous and irremediable medical condition. Because this is a new practice in Canadian health care, there are no published Canadian statistics on MAID cases to date, and this paper constitutes the first analysis of MAID cases in both the province of Ontario and Canada. Internationally, there are only a few jurisdictions with similar legislation already in place (US, the Netherlands, Belgium, Luxembourg, Switzerland, Columbia, Japan, and the United Kingdom). The published statistics on MAID cases from these jurisdictions were reviewed and used to establish the current global practices and demographics of MAID and will provide useful comparisons for Canada. This analysis will 1) outline the Canadian legislative approach to MAID, 2) provide an understanding of which patient populations in Ontario are using MAID and under what circumstances, and 3) determine if patterns exist between the internationally published MAID patient demographics and the Canadian MAID data. Selected patient demographics of the first 100 MAID cases in Ontario were reviewed and analyzed using anonymized data obtained from the Office of the Chief Coroner for Ontario so that an insight into the provision of MAID in Ontario could be obtained. Demographic factors such as age, sex, the primary medical diagnosis that prompted the request for MAID, the patient rationale for making a MAID request, the place where MAID was administered, the nature of MAID drug regimen used, and the status/specialty of medical personnel who administered the MAID drug regimen were analyzed. The analysis revealed that the majority of the first 100 MAID recipients were older adults (only 5.2% of patients were aged 35-54 years, with no younger adults between ages 18-34 years) who were afflicted with cancer (64%) and had opted for clinician-administered MAID (99%) that had been delivered in either a hospital (38.8%) or private residence (44.9%). Although the cohort was small, these Ontario MAID demographics reflect similar observations as those published internationally, but further analysis of both larger and annual case uptake in both Ontario and Canada will be conducted as the number of cases increases.
Trends in United States Mass Fatality Incidents and Recommendations for Medical Examiners and Coroners
Authors: Carroll Emily , Johnson Amy , DePaolo Frank , Adams Bradley J. , Mazone Dennis , Sampson Barbara 
Published: June 2018

It is imperative that medicolegal jurisdictions prepare for the occurrence of a mass fatality incident. Despite the trend to plan for catastrophic and complicated incidents, this analysis of recent mass fatality events seeks to better inform authorities regarding the scale and types of incidents that could potentially impact their jurisdiction. The guidance provided by this study serves as a tool to guide the development of plans, acquisition of appropriate resources, and training of staff. To perform this analysis, data were collected from mass fatality incidents occurring in the United States from January 1, 2000 to December 31, 2016 that resulted in ten or more fatalities. Specific data points were collected for each incident including the date, location, number of fatalities, incident type (e.g., man-made or natural), incident subtype, and description (e.g., mass shooting, hurricane, aviation). A total of 137 incidents fit the criteria for inclusion in the analysis, resulting in a total of 8462 fatalities. The average number of incidents was eight per year during the study period. The analysis demonstrates that most mass fatality incidents (88.8%) result in between ten and 50 fatalities and are variable based on incident type and geographic location. This study includes several large-scale incidents, which as outliers have influenced fatality management operations and preparedness efforts on a national level. In particular, the World Trade Center attack of September 11, 2001 and subsequent remains recovery and identification operations have served to inform the New York City Office of Chief Medical Examiner of the capabilities required to manage a complex, protracted victim identification process involving extensive body fragmentation and commingling. While the World Trade Center attack has been shown to be outside the normal trends of mass fatality incidents, it has nonetheless offered the medicolegal community several invaluable lessons.