bluuebunny/crossref_metadata_2025_split huggingface dataset:
Measuring child and adolescent emotional lability: How do questionnaire‐based ratings relate to experienced and observed emotion in everyday life and experimental settings?
Authors: Van Liefferinge Dagmar , Sonuga‐Barke Edmund , Danckaerts Marina , Fayn Kirill , Van Broeck Nady , van der Oord Saskia 
Published: May 2018

AbstractObjectivesEmotional lability (EL) is an important trans‐diagnostic concept that is associated with significant functional impairment in childhood and adolescence. EL is typically measured with questionnaires, although little is known about the ecological validity of these ratings. In this paper, we undertook 2 studies addressing this issue by examining the relationship between rating‐based measures of EL and directly measured emotional expressions and experiences. Furthermore, the associations between directly measured emotional expressions and experiences and attention‐deficit/hyperactivity disorder (ADHD) symptomatology were also examined, given the clear association of EL with ADHD in former research.MethodsIn Study 1, we examined the relationship between parental report of children's EL and ADHD, and children's emotional expressions in an experimental context (N = 67). In Study 2, we examined the relationship between parental ratings and real‐time measures of emotional experiences in daily life in adolescents (N = 65).ResultsEL ratings were associated with different elements of real‐time emotional experiences and expressions. Elements of emotional expressions but not emotional experiences were also associated with ADHD symptom reports.ConclusionsThese studies provide evidence for the ecological validity of EL ratings. Furthermore, they add evidence for the associations between EL and ADHD.
Precision of Calcified Structures Used for Estimating Age of Chain Pickerel
Authors: Bauerlien Cory J. , Cornett Marinda R. , Zielonka Emily A. , Crane Derek P. , Bulak James S. 
Published: May 2018

Abstract
With the exception of Northern Pike Esox lucius, there is a paucity of information on the precision of age estimates based on calcified structures for esocid species, especially Chain Pickerel E. niger. We estimated ages for 42 Chain Pickerel from Stevens Creek Reservoir on the Savannah River, South Carolina–Georgia. Ages were estimated using sectioned pelvic, pectoral, dorsal, and anal fin rays, scales, cleithra (sectioned and whole), and otoliths to assess precision between repeated readings (four readers). Precision was evaluated by calculating agreement among readers, CV, and mean absolute difference (MAD) in estimates between reader pairs. We tested for differences in precision of estimates among structures using linear mixed models with CV or MAD as the response. Finally, we used age bias plots to evaluate whether there were structure or reader-related systematic biases in estimates. Coefficient of variation and MAD were significantly related to structure type (CV: P = 0.006, MAD: P = 0.001) and mean estimated age (CV: P &lt; 0.001, MAD: P = 0.025). Precision was poor for all structures and poorest for age-0 fish; however, all analyses indicated that otoliths provided the most precise estimates. We observed agreement in estimates among all readers for 40% of the otoliths examined and consensus agreement for 74% of the estimates. Coefficient of variation for otoliths declined from 67% for fish with a mean estimated age of 0 years to 5% for age-4 fish. Conversely, MAD for otoliths increased from 0.34 years for fish with a mean estimated age of 0 to 0.46 years for age-4 fish. Estimates from all structures, except pectoral rays, were negatively biased compared with estimates from otoliths. We recommend the use of otoliths for age estimation of Chain Pickerel, but managers and researchers should be cognizant of and evaluate the potential effects of variability in age estimates among readers on their analyses.
Direct error in constitutive equation formulation for inverse heat conduction problem
Authors: Babaniyi Olalekan A. , Oberai Assad A. , Barbone Paul E. 
Published: May 2018

SummaryWe present a mixed numerical formulation that handles discontinuities well for scalar hyperbolic partial differential equations. The formulation is based on a least‐square error in the constitutive equation. It is motivated by scalar inverse diffusion problems with interior data and applies to convection of a passive scalar in a discontinuous compressible flow field. We motivate the need for a mixed formulation by discretizing using an irreducible finite element method and discuss some of the limitations of that approach. We then develop and prove that the mixed formulation is well posed and verify that it works for problems with continuous and discontinuous thermal conductivity distributions.
Trends in invasive prenatal diagnostic testing at a single institution
Authors: Awomolo Adeola , Palomares Kristy , Garcia Guadalupe Herrera , Rosen Todd , Duzyj Christina , Ashkinadze Elena 
Published: May 2018

AbstractObjectiveAs diagnostic methodologies evolve, we sought to determine whether invasive testing rates would decline, whether there would be a shift in indications for invasive testing, and whether the diagnostic yield would increase.MethodsWe conducted a retrospective, observational study from 2006 through 2015. We quantified the number of invasive procedures per year and examined what percentage of these procedures yielded abnormal results. We also examined the indications for testing and determined the trend of these indications during the study period.ResultsThe number of amniocenteses showed a steady decline (P < .05). The number of CVS procedures has increased and was recently equivalent to amniocentesis. The percentage of abnormal results steadily increased from 11.4% to 27.0% (P < .001). The abnormal aneuploidy screening indication remained constant over time. Advanced maternal age (AMA) as the sole indication substantially declined from 42.3% to 15.52% (P < .001). Testing for a known single gene disorder steadily increased from 3.0% to 9.20% (P = .018).ConclusionOur study showed a significant decline in the number of amniocenteses, a steady increase in the percentage of abnormal results from invasive testing, and a decline in AMA as the sole indication for invasive testing.
Tumor heterogeneity, aggressiveness, and immune cell composition in a novel syngeneic PSA‐targeted Pten knockout mouse prostate cancer (MuCaP) model
Authors: van Duijn Petra W. , Marques Rute B. , Ziel‐van der Made Angelique C.J. , van Zoggel Hanneke J.A.A. , Aghai Ashraf , Berrevoets Cor , Debets Reno , Jenster Guido , Trapman Jan , van Weerden Wytske M. 
Published: May 2018

BackgroundProstate cancer is recognized as a heterogeneous disease demanding appropriate preclinical models that reflect tumor complexity. Previously, we established the PSA‐Cre;PtenLoxP/LoxP genetic engineered mouse model (GEMM) for prostate cancer reflecting the various stages of tumor development. Prostate tumors in this Pten KO model slowly develop, requiring more than 10 months. In order to enhance its practical utility, we established a syngeneic panel of cell lines derived from PSA‐Cre targeted Pten KO tumors, designated the mouse prostate cancer (MuCap) model.MethodsFour different MuCaP epithelial cell lines were established from three independent primary Pten KO mouse prostate tumors. Tumorigenic capacity of the MuCaP cell lines was determined by subcutaneous inoculation of these cell lines in immunocompetent mice. Response to PI3K‐targeted therapy was validated in ex vivo tissue slices of the established MuCaP tumors.ResultsThe MuCaP cell lines were all tumorigenic in immunocompetent mice after subcutaneous inoculation. Interestingly, these syngrafted tumors represented different tumor growth rates and morphologies. Treatment with the specific PI3K inhibitor GDC0941 resulted in responses very similar between syngeneic MuCaP and primary Pten KO prostate tumors. Finally, immunoprofiling of the different syngeneic MuCaP tumors demonstrated differential numbers of tumor infiltrating lymphocytes and distinct immune gene profiles with expression of CD8, INFy, and PD1 being inversely related to tumor aggressiveness.ConclusionsCollectively, we present here a well‐defined MuCaP platform of in vitro and in vivo mouse prostate cancer models that may support preclinical assessment of (immune)‐therapies for prostate cancer.
Rapid Sonochemical Synthesis of an Intercalated Superconductor
Authors: Yang Zhanhai , He Junbao , Zang Xiaoling , Wang Xusheng , Ren Zhian , Xue Mianqi , Chen Genfu 
Published: May 2018

AbstractThe synthesis of new superconducting materials is a perennially topic of intense interest since the discovery of superconducting materials. To capture possible superconductors abundantly and effectively, wet‐chemical technique, as one of the most common chemical synthesis method, has been introduced to seek new superconductors and achieved great success in almost every category. However, conventional liquid‐phase method imposes requirements on the undesirable reaction time, which dramatically sacrifices the innovative efficiency of superconductors. To facilitate the synthesis process, through the application of sonochemical method, here we successfully bulid a fast‐synthesis and easy‐implementation procedure to explore intercalated superconductors.
Water‐Mediated Synthesis of Anthelmintic Piperidinols and Their Molecular Docking Studies
Authors: Jagadale Megha B. , Salunkhe Rajashri S. , Rajmane Mohan M. , Dhanavade Maruti J. , Sonawane Kailas D. , Rashinkar Gajanan S. 
Published: May 2018

AbstractA simple, inexpensive and environmentally benign protocol for the synthesis of piperidinols is reported by reactions of Mannich bases with primary alkyl amines in water. The synthesized piperidinols displayed potential anthelmintic activity against Indian adult earthworm. The activity profile of piperidinols was correlated with their molecular docking results.
A De Novo Approach for the Stereoselective Synthesis of Cyclopenta[c]pyranone Scaffold Present in Iridoids: Formal Syntheses of Isoboonein, Iridomyrmecin and Isoiridomyrmecin
Authors: Kaurav Manvendra Singh , Kumar Virendra , Kumar Dileep , Khan Tabrez 
Published: May 2018

AbstractA conceptually new intramolecular Pauson‐Khand reaction (IPKR) based general strategy has been demonstrated for the formal syntheses of isoboonein, iridomyrmecin and isoiridomyrmecin from very cheap, commercially available starting material.
New Chloro‐Based Azo‐Azomethine Dyes: Synthesis, Biological and Optical Spectroscopic Studies for Detection of some Transition Metal Ions
Authors: Shaghaghi Zohreh , Rezanezhad Rezvaneh 
Published: May 2018

AbstractTwo new chromogenic receptors 1,2‐[1‐(3‐imino‐4‐hydroxophenylazobenzene)]‐4‐chlorobenzene (1 a) and 1,2‐[1‐(3‐imino‐4‐hydroxophenylazo‐4‐nitrobenzene)]‐4‐chlorobenzene (1 b) have been designed and chearcterized for detection of some transition metal ions in DMSO solution by UV/Vis spectroscopy. Upon addition of Cd2+, Zn2+ and Cu2+ ions to 1 a in DMSO, the peak at 460 nm increases in intensity, while the band at 352 nm decreases in intensity and approximately disappears. n→π* transition of azo groups of 1 a decreases in intensity after adding Hg2+ ions and does not change after adding Ni2+ ions. This indicates high tendency of 1 a towards Cd2+, Zn2+ and Cu2+ against Ni2+ and Hg2+ions. Compound 1 b shows some color changes after addition of metal ions. Upon addition of all metal ions to 1 b in DMSO, the band at 560 nm increases in intensity with the hypsochromic shift for Cu2+, Zn2+, Co2+ and Ni2+. But the largest blue shift (‐67 nm) is seen after adding Cu2+ ion with remarkable color change from violet‐green to orange. Benesi‐ Hildebrand plot and Job′s method are used for determination of binding constant (Ka) and stoichiometry of formed complexes with 1 b. Then, complex Cu(II) with 1 b is synthezied for recognition of binding sites of ligand. The results indicate that 1 b behaves as one tetradentate ligand with N and O donor atoms when bound to Cu(II). Moreover, the study of antioxidant properties of 1 a and 1 b with DPPH method reveals good and significant activity.
An Approach for Synthesis of Dithioacetals by CuI‐Catalyzed C‐S Coupling Reaction of N‐Tosylhydrazone with Disulfides
Authors: Zhang Zhang , Kong Peng , Wang Xi–Cun 
Published: May 2018

AbstractA copper (I) catalyzed C−S bond formation by reaction of N‐tosylhydrazones and disulfides is developed. A variety of N‐tosylhydrazones underwent coupling reaction with various disulfides successfully to afford the corresponding dithioacetals in moderate to good yields.
Direct C‐H Bond Arylation of C2‐Blocked Pyrrole with Aryl Halides Using Palladium(II)‐N‐Heterocyclic Carbene Catalysts
Authors: Kaloğlu Murat , Kaloğlu Nazan , Özdemir İsmail 
Published: May 2018

AbstractHerein we report synthesis of seven new palladium(II)‐NHC complexes with the general formula [PdX2(NHC)2], (NHC=1,3‐dialkylbenzimidazol‐2‐ylidene, X=Cl or Br). The structures of all the new compounds were characterized by 1H NMR, 13C NMR, FT‐IR spectroscopy and elemental analysis techniques. The catalytic activities of palladium(II)‐NHC complexes were tested in the direct C−H bond arylation of C2‐blocked pyrrole with various aryl halides in presence of 1 mol% catalyst loading at 120 °C for 1–16 h. Under the given conditions, palladium(II)‐NHC complexes showed the good catalytic performance for the direct C−H bond arylation of C2‐blocked pyrrole with aryl bromides, and with readily available and inexpensive aryl chlorides. In all cases, the C−H bond arylation regioselectively produced C5‐arylated products in moderate to high yields.
A Straightforward Synthesis of α‐Amino Diaryl Ketones from (Hetero)Arylacetonitriles Promoted by N‐Bromosuccinimide
Authors: Kumar Yogesh , Jaiswal Yogesh , Thakur Rima , Kumar Amit 
Published: May 2018

AbstractA facile and straightforward approach has been developed for the synthesis of α‐amino diaryl ketones. This strategy utilizes simple, cheap, stable, non‐toxic arylacetonitriles as a key starting material and is effectively promoted by N‐Bromosuccinimide. This reaction proceeds via the involvement of three consecutive steps in a one‐pot manner without isolating any intermediates and displays remarkable functional group tolerance. Gram‐scale syntheses of α‐amino ketone demonstrate the practicality of the protocol.
Rational Design of Hierarchically Core–Shell Structured Ni3S2@NiMoO4 Nanowires for Electrochemical Energy Storage
Authors: Chen Fangshuai , Ji Shan , Liu Quanbing , Wang Hui , Liu Hao , Brett Dan J. L. , Wang Guoxiu , Wang Rongfang 
Published: May 2018

AbstractRational design and controllable synthesis of nanostructured materials with unique microstructure and excellent electrochemical performance for energy storage are crucially desired. In this paper, a facile method is reported for general synthesis of hierarchically core–shell structured Ni3S2@NiMoO4 nanowires (NWs) as a binder‐free electrode for asymmetric supercapacitors. Due to the intimate contact between Ni3S2 and NiMoO4, the hierarchical structured electrodes provide a promising unique structure for asymmetric supercapacitors. The as‐prepared binder‐free Ni3S2@NiMoO4 electrode can significantly improve the electrical conductivity between Ni3S2 and NiMoO4, and effectively avoid the aggregation of NiMoO4 nanosheets, which provide more active space for storing charge. The Ni3S2@NiMoO4 electrode presents a high areal capacity of 1327.3 µAh cm−2 and 67.8% retention of its initial capacity when current density increases from 2 to 40 mA cm−2. In a two‐electrode Ni3S2@NiMoO4//active carbon cell, the active materials deliver a high energy density of 121.5 Wh kg−1 at a power density of 2.285 kW kg−1 with excellent cycling stability.
Excellent Fog‐Droplets Collector via Integrative Janus Membrane and Conical Spine with Micro/Nanostructures
Authors: Zhou Hu , Zhang Miaoxin , Li Chang , Gao Chunlei , Zheng Yongmei 
Published: May 2018

AbstractInspired by a cactus spine and trichomes integrated fog collection system, a strategy is presented to design a micro/nanostructured conical spine and Janus membrane integrative system (MNCS+JM). In this strategy, the surface of conical spine can be covered with rough micro and nanostructure (MNCS), so that the tiny fog‐droplets can be captured, coalesced, and transported. Janus membrane (JM) with inside hydrophobic surface and outside hydrophilic surface is further used to control the water collection in process of droplet transport when the Janus membrane is vertically placed with different positions on the MNCS, thus MNCS+JM propel the droplet continuously for transport–coalescence–transport in a circle of droplet transport and collection. It is demonstrated that a higher fog collection rate can be achieved effectively, which is attributed to a cooperation effect between the Laplace pressure in difference and the released surface energy in droplet coalescence, in addition to wettability force of superhydrophobic–hydrophilic difference in the Janus membrane. This strategy of MNCS+JM offers an insight into the surface of materials to control the droplet transport for water collection in efficiency, which is significant to be extended into the realms of applications such as high‐efficiency water collection systems, microfluidics devices, and others.
A graph grammar‐based approach for graph layout
Authors: Liu Yufeng , Zeng Xiaoqin , Zou Yang , Zhang Kang 
Published: May 2018

SummaryAs a two‐dimensional formal tool, graph grammars are capable of handling the layout problems of visual programming languages. Based on an edge‐based graph grammar (EGG), this paper proposes a novel layout approach that uses the unique features of EGG and overcomes the weakness of existing layout approaches. In order to make the approach rigorous yet concise, the graph grammar mechanisms with layout constraints and quantitative analysis techniques are combined together as an integrity. First, the basic notions of EGG are briefly introduced; second, the layout approach is presented that consists of two phases, ie, bottom‐up parsing and top‐down derivation. Finally, a case study is given by taking the standard flowchart as an example to demonstrate the working process of the proposed approach.
Formally modeling and analyzing cost‐aware job scheduling for cloud data center
Authors: Fan Guisheng , Chen Liqiong , Yu Huiqun , Liu Dongmei 
Published: May 2018

SummaryWith the rapid development of cloud computing, many distributed data centers have been deployed. This means larger energy consumption requirements from the data center. How to reduce the cost of data center has received significant attention recently. Although there are several efforts in studying energy consumption of the data center, very few have considered modeling and analyzing cost‐aware job scheduling for the cloud data center. To address this emerging problem, we propose a systematic approach that considers both basic elements and their relationships in cloud data center. First, we present a formal language to describe the cloud data center, and a job scheduling net is proposed to formally model the basic elements such as user request, Web portal, data center, and server. Second, we minimize the total cost of the cloud data center by considering the multidimensional resource and local electricity price on the basis of the state space of constructed model. The dynamic job scheduling algorithm and its specific execution steps are proposed based on the alternating direction method of multipliers algorithm. Third, the operational semantics and related theories of Petri nets for establishing the correctness of our proposed method are presented. Finally, a series of simulations are performed to illustrate that the proposed method can guarantee the correct behavior of job scheduling in the cloud data center while meeting the required cost.
An energy‐aware resource provisioning scheme for real‐time applications in a cloud data center
Authors: Faragardi Hamid Reza , Dehnavi Saeid , Nolte Thomas , Kargahi Mehdi , Fahringer Thomas 
Published: May 2018

SummaryBased on a pay‐as‐you‐go model, cloud computing provides the possibility of hosting pervasive applications from both academic and business domains. However, data centers hosting cloud applications consume huge amounts of electrical energy, contributing to high operational costs and large carbon footprints to the environment. Energy‐aware resource provisioning is an effective solution to diminish the energy consumption of cloud data centers. Recently, a growing trend has emerged, where cloud technology is used to run periodic real‐time applications such as multimedia, telecommunication, video gaming, and industrial applications. In order for a real‐time application to be able to use cloud services, cloud providers have to be able to provide timing guarantees. In this paper, we introduce an energy‐aware resource provisioning mechanism for cloud data centers, which are capable of serving real‐time periodic tasks following the Software as a Service model. The proposed method is compared against an energy‐aware version of the RT‐OpenStack. RT‐OpenStack is a recently proposed approach to provide a time‐predictable version of OpenStack. The experimental results manifest that our proposed resource provisioning method outperforms energy‐aware version of the RT‐OpenStack by 16.01%, 25.45%, and 25.45% in terms of energy consumption, number of used servers, and average utilization of used servers, respectively. Moreover, from the scalability perspective, the preference of the proposed method for large‐scale data centers is more considerable.
Corrections to: Enhanced lincomycin production by co‑overexpression of metK1 and metK2 in Streptomyces lincolnensis
Authors: Xu Yurong , Tan Guoqing , Ke Meilan , Li Jie , Tang Yaqian , Meng Sitong , Niu Jingjing , Wang Yansheng , Liu Ruihua , Wu Hang , Bai Linquan , Zhang Lixin , Zhang Buchang 
Published: May 2018

Abstract
In the online published article, row value “pIB139-metK1-metK2” in table 1 has been processed incorrectly. The correct table is given below
Recent review of transcatheter closure of atrial septal defect
Authors: Yang Ming‐Chun , Wu Jiunn‐Ren 
Published: May 2018

AbstractAtrial septal defect (ASD) is one of the two most common congenital heart diseases in children and adult. After the application of catheter intervention for ASD, this became an alternative treatment other than surgery from late 1990. In 2001, the procedure was further approved by the US Food and Drug Administration (FDA), and become the first choice for most cases of secundum type of ASD worldwide. The success rate is more than 98% in literature reviews, with low complication rates in percutaneous ASD closure. Major complications are around 1%, including device embolization, cardiac erosions, new‐onset atrial arrhythmia, and other comorbidities. We reviewed indications for percutaneous secundum type ASD closure, technique, successful rate and major complications in this article. To complete the catheter intervention with difficult ASD conditions, various procedural techniques have been developed recently. We also report a challenging case by a current balloon‐assisted technique for huge ASD closure.