bluuebunny/crossref_metadata_2025_split huggingface dataset:
Person-Centered Integrated Care for Chronic Kidney Disease
Authors: Valentijn Pim P. , Pereira Fernando Abdalla , Ruospo Marinella , Palmer Suetonia C. , Hegbrant Jörgen , Sterner Christina W. , Vrijhoef Hubertus J.M. , Ruwaard Dirk , Strippoli Giovanni F.M. 
Published: February 2018

Background and objectivesThe effectiveness of person-centered integrated care strategies for CKD is uncertain. We conducted a systematic review and meta-analysis of randomized, controlled trials to assess the effect of person-centered integrated care for CKD.Design, setting, participants, & measurementsWe searched MEDLINE, Embase, and Cochrane Central Register of Controlled Trials (from inception to April of 2016), and selected randomized, controlled trials of person-centered integrated care interventions with a minimum follow-up of 3 months. Random-effects meta-analysis was used to assess the effect of person-centered integrated care.ResultsWe included 14 eligible studies covering 4693 participants with a mean follow-up of 12 months. In moderate quality evidence, person-centered integrated care probably had no effect on all-cause mortality (relative risk [RR], 0.86; 95% confidence interval [95% CI], 0.68 to 1.08) or health-related quality of life (standardized mean difference, 0.02; 95% CI, −0.05 to 0.10). The effects on renal replacement therapy (RRT) (RR, 1.00; 95% CI, 0.65 to 1.55), serum creatinine levels (mean difference, 0.59 mg/dl; 95% CI, −0.38 to 0.36), and eGFR (mean difference, 1.51 ml/min per 1.73 m2; 95% CI, −3.25 to 6.27) were very uncertain. Quantitative analysis suggested that person-centered integrated care interventions may reduce all-cause hospitalization (RR, 0.38; 95% CI, 0.15 to 0.95) and improve BP control (RR, 1.20; 95% CI, 1.00 to 1.44), although the certainty of the evidence was very low.ConclusionsPerson-centered integrated care may have little effect on mortality or quality of life. The effects on serum creatinine, eGFR, and RRT are uncertain, although person-centered integrated care may lead to fewer hospitalizations and improved BP control.
Benchmarking data from the experience gained in engine performance and emissions testing on alternative fuels for aviation
Authors: Chishty Wajid A. , Chan Tak , Canteenwalla Pervez , Davison Craig R. , Chalmers Jennifer 
Published: February 2018

Abstract
Alternative fuel for aviation has been the centre of serious focus for the last decade, owing mostly to the challenges posed by the price of conventional petroleum fuel, energy security and environmental concerns. The downslide in the oil prices in the recent months and the fact that energy security is not considered a major threat in commercial aviation, these factors have worked negatively for the promotion of alternative fuels. However, the continuous commitment to environmental stewardship by Governments and the industry have kept the momentum going towards the transparent integration of renewable alternatives in the aviation market. On the regulatory side, much progress have been made in the same timeframe with five alternative fuels being certified as synthetic blending components for aviation turbine fuels for use in civil aircraft and engines. Another seven alternative fuels are in the various stages of certification protocol. This progress has been made possible because of the extensive performance testing, both at full engine conditions and at engine components level. This article presents the results of engine performance and air pollutant emissions measurements gathered from the alternative fuels qualification testing conducted at the National Research Council Canada over the last seven years. This benchmarking data was collected on various engine platforms at full engine operation at sea level and/or altitude conditions using a variety of aviation alternative fuels and their blends. In order to provide a reference comparison basis, the results collected using the alternative fuels are compared with baseline Jet-A1 or JP-8 conventional fuels.
Case Study of Load Shifting Using Thermal Energy Ice Storage in Public Facilities
Authors: Whitcraft Dan , Sullivan Kenneth T. , Saseendran Anusree , Smithwick Jake 
Published: February 2018

ABSTRACT
Energy management is becoming increasingly important in the building sector due to the fact that it accounts for 50% of total energy consumption in industrial nations. The objective of this study was to compare a partial thermal energy storage system and a traditional air-cooled chiller system in a building retrofit in Alachua County, Florida in order to identify energy and cost savings and to quantify those savings. Initial costs, maintenance costs, energy consumption and utility rates were used to draw comparisons between the two systems. Findings include annual utility costs and annual operating costs for the two systems, and their simple payback period. The Thermal Energy System (TES) was found to be more beneficial in the long run, despite its higher cost of installation. Practical implications of implementing an advanced system such as TES are discussed to better prepare building professionals considering TES.
Antisense Inhibition of Protein Tyrosine Phosphatase 1B With IONIS-PTP-1BRx Improves Insulin Sensitivity and Reduces Weight in Overweight Patients With Type 2 Diabetes
Authors: Digenio Andres , Pham Nguyen C. , Watts Lynnetta M. , Morgan Erin S. , Jung Shiangtung W. , Baker Brenda F. , Geary Richard S. , Bhanot Sanjay 
Published: February 2018

OBJECTIVE
To evaluate safety and efficacy of IONIS-PTP-1BRx, a second-generation 2′-O-methoxyethyl antisense inhibitor of protein tyrosine phosphatase 1B, as add-on therapy in overweight patients with type 2 diabetes inadequately controlled with metformin with or without sulfonylurea therapy.

RESEARCH DESIGN AND METHODS
In this phase II, double-blind, randomized, placebo-controlled, multicenter trial, overweight and obese patients (BMI ≥27 kg/m2) with type 2 diabetes (HbA1c ≥7.5% [58 mmol/mol] and ≤10.5% [91 mmol/mol]) on a stable dose of metformin alone or with sulfonylurea were randomized 2:1 to IONIS-PTP-1BRx 200 mg (n = 62) or placebo (n = 30) once weekly for 26 weeks.

RESULTS
Mean baseline HbA1c was 8.6% (70 mmol/mol) and 8.7% (72 mmol/mol) in placebo and active treatment, respectively. At week 27, IONIS-PTP-1BRx reduced mean HbA1c levels by −0.44% (−4.8 mmol/mol; P = 0.074) from baseline and improved leptin (−4.4 ng/mL; P = 0.007) and adiponectin (0.99 μg/mL; P = 0.026) levels compared with placebo. By week 36, mean HbA1c was significantly reduced (−0.69% [−7.5 mmol/mol]; P = 0.034) and accompanied by reductions in fructosamine (−33.2 μmol/L; P = 0.005) and glycated albumin (−1.6%; P = 0.031) versus placebo. Despite both treatment groups receiving similar lifestyle counseling, mean body weight significantly decreased from baseline to week 27 with IONIS-PTP-1BRx versus placebo (−2.6 kg; P = 0.002) independent of HbA1c reduction (R2 = 0.0020). No safety concerns were identified in the study.

CONCLUSIONS
Compared with placebo, IONIS-PTP-1BRx treatment for 26 weeks produced prolonged reductions in HbA1c, improved medium-term glycemic parameters, reduced leptin and increased adiponectin levels, and resulted in a distinct body weight–reducing effect.
Limb- and Person-Level Risk Factors for Lower-Limb Amputation in the Prospective Seattle Diabetic Foot Study
Authors: Boyko Edward J. , Seelig Amber D. , Ahroni Jessie H. 
Published: February 2018

OBJECTIVE
Diabetes is the leading cause of nontraumatic lower-limb amputations in the U.S., but no research has prospectively examined associations between limb-specific measurements and amputation risk among patients without foot ulcer. We investigated amputation risk by limb in relation to the same limb- and person-level factors.

RESEARCH DESIGN AND METHODS
We conducted a 22-year prospective study among 1,461 male patients with diabetes without foot ulcer (mean age 62.4 years), with 2,893 lower limbs among subjects recruited between 1990 and 2002 from one Department of Veterans Affairs general internal medicine clinic. The following information was collected: demographic, lifestyle, and diabetes characteristics; visual acuity; kidney function (estimated glomerular filtration rate [eGFR]); and lower-limb measurements including presence of Charcot deformity, sensory neuropathy by 10-g monofilament, dorsal foot transcutaneous oximetry (TcPO2) at 44°C, and ankle-brachial index (ABI).

RESULTS
Over 25,735 limb-years, 136 amputations occurred. A multivariable Cox model identified multiple independent risk factors: sensory neuropathy (hazard ratio 3.09 [95% CI 2.02–4.74]), ABI ≤0.5 vs. &gt;0.9 to &lt;1.3 (3.98 [2.31–6.85]), ABI ≥1.3 vs. &gt;0.9 to &lt;1.3 (2.20 [1.18–4.09]), 1-SD decrease in eGFR (1.18 [1.00–1.38]), poor vision (1.70 [1.05–2.73]), body weight in 21.4-kg increments (0.78 [0.61–0.98]), and age &gt;70 years vs. &lt;57 years (0.13 [0.04–0.38]). Although TcPO2 was not significantly associated with amputation overall, TcPO2 &lt;26 mmHg significantly predicted a higher risk in the ABI ≥1.3 category.

CONCLUSIONS
Arterial disease and neuropathy emerged as the only limb-specific risk factors for amputation, but these and several person-level factors may be amenable to prevention or treatment interventions to potentially reduce diabetic amputation risk.
Physiological performance of sunflower genotypes under combined salt and drought stress environment
Authors: Umar Muhammad , Siddiqui Zamin Shaheed 
Published: February 2018

AbstractThe physiological performance of some sunflower genotypes (S.28111, SF0049, Hysun-33, Hysun-39) under salt, drought stress separately and in combination was examined. Salt, drought and a combination of these stresses were applied to plants by gradual increments. The plants were exposed to stress for two weeks. Relative water content, osmotic potential, stomatal conductance, performance index, dark adapted quantum yield and chlorophyll contents were reduced upon salinity and drought stresses. However, when plants were subjected to a combination of these stresses, a greater reduction in all tested attributes was observed. Proline and carotenoid contents in drought stress were elevated compared to salt stress. Superoxide dismutase (SOD) and catalase (CAT) showed the highest activity in individual salt and drought stress with less accumulation of H2O2. Combined stress reduced the activity of antioxidant enzymes which ultimately decreased the physiological performance of sunflower plants. However, among the tested genotypes, S.28111 and SF0049 were found to be more tolerant to drought, salt and combined stress than both Hysun genotypes. The physiological performance of genotypes against salinity and drought individually and in combination is discussed in detail.
A new addition to the alien flora of Tunisia, Amaranthus spinosus L. (Amaranthaceae s.l.), with notes on A. diacanthus Raf.
Authors: Iamonico Duilio , Mokni Ridha El 
Published: February 2018

Abstract
Amaranthus spinosus L. (Amaranthaceae s.l.), a species native to the Neotropics, has been found in four localities (Bizerta, Bir Bouregba, Hammamet, and Nabeul) of N. Tunisia. Our discovery represents the first record at national level, and the second one for N. Africa. Morphological characters and ecological data are given. Nomenclatural notes are provided for the name A. diacanthus, which was regarded by some authors as heterotypic synonym of A. spinosus. A neotype is designated in the present paper based on a specimen preserved at LSU.
Photosynthetic performance of two freshwater red algal species
Authors: Pálmai Tamás , Szabó Beáta , Hubai Katalin Eszter , Padisák Judit 
Published: February 2018

Abstract
Photosynthetic performances of two freshwater red algal populations from freshwaters of the Carpathian basin were measured in this study. Populations were collected from different habitats: Bangia atropurpurea from Lake Balaton and Batrachospermum gelatinosum from the Tapolca stream. Their photosynthesis was studied in a wide range of temperature (5–35 °C) and light intensity (0–1150 μmol m−2 s−1) in a photosynthetron. We found both species’ photosynthesis maxima at 25 °C but B. atropurpurea had significantly higher photosynthetic production. Low and medium values were calculated for the species’ photoadaptation parameters. Compensation light intensities determined in this study were similar to those obtained in previous studies. Both species utilized light efficiently; photoinhibition was detected only at two measuring temperatures for Bangia and at four measuring temperatures for Batrachospermum. P-T characteristics of the species revealed that both have temperature optima at 25 °C under high and medium light intensities but there are no such remarkable optima at low irradiance. The biomass specific respiration of both species increased with increasing temperature. We confirmed the good light utilization of these red algal species but found temperature optima higher than reported previously.
Bryophytes and heavy metals: a review
Authors: Stanković Jelena D. , Sabovljević Aneta D. , Sabovljević Marko S. 
Published: February 2018

Abstract
Bryophytes, a group of terrestrial plants widely used in biomonitoring, are reviewed for their relation to heavy metals. In the present article, we summarized the knowledge on heavy metals pollution and accumulation effects on bryophytes. Mechanisms of tolerance and resistance are given as well.
Analysis of Road Traffic Safety in Minna Niger State, Nigeria
Authors: Oyetubo Adebayo Owolabi , Afolabi Oluwaseyi Joseph , Ohida Muhammed Etudaiye 
Published: February 2018

Abstract
Road traffic accident is one of the major causes of death in Nigeria. Road accidents have taken away so many lives in Nigeria today that hardly does any single disease match its mortality prowess. People have died prematurely and properties worth several millions of Naira have been lost as a result of road traffic accident. This paper gives a full discussion on road traffic safety issues and the methodology used were through the collection of data using questionnaire and accident information from the Nigeria Police Force, FRSC etc. The primary information for this research was sourced through the use of structured questionnaire, personal observation and interviews of road users in the study area. Secondary data emanated from published and unpublished sources such as government records, internet, journals, books etc. The findings were presented in descriptive and inferential form using frequencies, percentages, tables, mean and chi-square analytical techniques. The findings from the study revealed among many others; that Male involved more in road accident compare to female counterpart in Minna Niger State. Private car had more accident compare to Taxi, The number of accident in each zone does not depend on the population of that zone, etc.
Prevalence of Gastrointestinal Parasitism Infections in Cattle of Bass Kabylie Area: Case of Bejaia Province, Algeria
Authors: Moussouni Lotfi , Benhanifia Mokhtar , Saidi Mokhtar , Ayad Abdelhanine 
Published: February 2018

Abstract
The objective of this study was to determine the prevalence, identification of species and the dynamics of gastrointestinal (GI) parasites during humid and dry seasons in local cattle of different ages. The study was carried out in the Province of Bejaia, Algeria from December 2013 to June 2014. A total of 143 fecal samples were collected from different cattle herds. Fecal samples were visually examined then observed using flotation and sedimentation microscopic techniques. Eggs and worms were identified according to standard procedures. 63% of the cattle examined were found positive with one or more parasite species. Our results revealed that the eggs of Eimeria spp. are predominant (43.87%) followed by Strongylus spp. (30.32%) and Fasciola hepatica (12.25%). Eggs of Strongyloides papillosus, Moniezia benedeni, Paramphistomum daubneyi. and Toxocara vitulorum represent 1.29%, 1.93%, 1.93% and 6.45%, respectively. There is a significant difference between the sex of the animal and the prevalence rate of Strongyle spp. and Eimeria spp. (P< 0.01
). As for the body condition score, there is a statically significant (P< 0.01
) difference between the prevalence rate of GI parasite and the nutritional status of cattle. In conclusion, our preliminary investigation demonstrated highly prevalent and that abundance of the polyparasitism nature of the disease in Bass Kabylie area. Also, there was a relationship between the distribution of GI parasitism in cattle and the factors analyzed (body condition score, age and sex). Further studies are need for planning future research and to design rational and sustainable locally GI parasites control programmes.
APLIKASI SIG UNTUK PEMETAAN ZONA KETERPAPARAN PERMUKIMAN TERHADAP TSUNAMI
Authors: Hadi Fakhri 
Published: February 2018

<p>Kota Pariaman merupakan salah satu kota di Indonesia yang terindikasi rawan terhadap bencana tsunami dikarenakan lokasinya yang berada di pinggir pantai serta berbatasan langsung dengan Samudera Hindia. Permukiman merupakan salah satu aset yang harus dijaga. Pemetaan zona keterpaparan permukiman terhadap tsunami diperlukan demi menjaga penduduk yang bertempat tinggal di kota tersebut serta sebagai acuan dalam mitigasi bencana dan meminimalkan kerugian akibat bencana tersebut. Pemetaan ini bertujuan untuk menaksir tingkat keterpaparan permukiman terhadap bencana tsunami. Tingkat keterpaparan dilihat dari dua komponen, yaitu tingkat bahaya (<em>hazard</em>), serta <em>element at risk. </em>Tingkat bahaya tsunami dilihat dari<em> </em>jarak dari garis pantai, ketinggian, wilayah lereng, serta jarak dari sungai sedangkan <em>Element at risk </em>atau elemen yang terkena bencana tsunami yaitu permukiman. Pemetaan keterpaparan ini menggunakan teknik <em>overlay</em>, metode skoring dan pembobotan dengan menggunakan <em>software ArcMap 10.1 </em>sebagai salah satu pendekatan berbasis Sistem Informasi Geografis (SIG). Hasil penelitian menunjukkan bahwa tingkat keterpaparan permukiman di Kota Pariaman terhadap tsunami didominasi oleh tingkat keterpaparan sedang dengan luas 963,07 hektar, kemudian disusul oleh tingkat keterpaparan tinggi dengan luas 572,60 hektar, serta tingkat keterpaparan rendah dengan luas 121,98 hektar. Permukiman di Kota Pariaman yang terpapar tinggi terhadap tsunami cenderung berada di wilayah yang landai, serta dekat dengan pantai.</p><p class="abstract"><strong>Kata Kunci: </strong>Keterpaparan, Permukiman, SIG, Tsunami</p>
PEMETAAN BANDARA UNTUK PEMBANGUNAN INFRASTRUKTUR LANJUTAN
Authors: Sitanggang Maludin 
Published: February 2018

<p>Bandara sebagai pelabuhan udara merupakan fasilitas tempat pesawat terbang untuk lepas landas dan mendarat yang dilengkapi berbagai fasilitas, baik untuk operator layanan penerbangan maupun bagi penggunanya. Hal ini mempercepat arus lalu lintas penumpang, kargo dan servis melalui transportasi udara di setiap pelosok guna mempercepat perekonomian. Naik turun penumpang, bongkar muat barang, dan tempat perpindahan intra dan antarmoda transportasi harus dilengkapi dengan fasilitas keselamatan dan keamanan penerbangan, serta fasilitas penunjang lainnya. Dengan berkembangnya dunia penerbangan, keberadaan bandar udara menjadi sangat strategis. Di beberapa wilayah Indonesia, banyak direncanakan membangun bandara internasional, tentu keberadaan bandara menjadi kebutuhan masyarakat. Selain manfaatnya yang banyak, keberadaan bandara akan dirasakan menjadi masalah bahkan mengganggu terhadap sebagian masyarakat, terutama yang tinggal di sekitar bandara. Pengaruh aktivitas bandara terhadap lingkungan dan fasilitas umum lainnya akan terjadi perubahan drastis. Sehingga pembangunan bandara ditinjau dari aspek fisik, aspek sosial dan aspek ekonomi, serta geliat pariwisata. Dengan adanya bandara, wujud fisik perkembangan kota memiliki intensitas kegiatan yang tinggi sehingga keberadaan fasilitas bandara bisa tidak lagi berada di pusat kota. Dengan banyaknya bandara, maka perlu dilakukan pemetaan agar tidak mengganggu pembangunan infrastruktur dalam wilayah potensial tertentu. Oleh karena itu pembangunan infrastruksur lanjutan disuatu wilayah akan pesat dengan adanya pemetaan bandara yang sudah ada maupun yang akan di bangun.</p><strong>Kata kunci </strong>: pesawat, wilayah, infrastruktur
PENGARUH CAMPURAN COCOPEAT DAN ROCK PHOSPHATE TERHADAP PERTUMBUHAN DAN HASIL TIGA VARIETAS PADI GOGO (Oryza sativa L.) PADA MEDIUM ULTISOL
Authors: Yulia Rahmi , Nelvia Nelvia , Ariani Erlida 
Published: February 2018

The research aims to study the effect of mixture of cocopeat and rock phosphate on growth and yield of three varieties of upland rice in Ultisols medium. The research was conducted at the Green House of the Faculty of Agriculture, University of Riau, Pekanbaru from March to August 2017. The research used Split Plot Design. The main plot were upland rice consist of three varieties (Situ Bagendit, Situ Patenggang and Inpago 8). The subplots were mixture of cocopeat 10 t ha-1 with rock phosphate (RP) doses 0, 30, 45, and 60 P2O5 kg ha-1. The parameters observed were plant height, number of maximum tillers and productive tillers, panicle length, flowering age, number of grain panicle-1, weight of dry milled grain and weight of 1000 grain. The results showed that the application of mixture of cocopeat doses 10 t ha-1 and RP doses 30 – 60 P2O5 kg ha-1 have effect to plant height, panicle length, and weight 1000 grain for Situ Bagendit, Situ Patenggang and Inpago 8 compare to without RP, but tended increase number of maximum and productive tillers and decrease flowering age. The application cocopeat doses 10 t ha-1 and RP doses 30 P2O5 kg ha-1 increased number of filled grain panicle-1 and weight of dry milled grain on three varieties, weight of dry milled grain Situ Patenggang > Inpago 8 > Situ Bagendit on each doses of RP and have number of productive tillers of these varieties 1,5 – 2 is greater than its descriptions.Keywords : rock phosphate, ultisol, upland rice
Mejora de los procesos de lectura a través del Programa MATEL
Authors: Molina Roldan Rosa M. , Pérez Segura Francisco , Molina Roldán Adela M. 
Published: February 2018

Introducción. En la presente investigación pretendimos estudiar la relación existente entre la comprensión, la velocidad y la eficacia lectora. El hecho que motivó la investigación, fue la constatación de la relación existente entre déficit de lectura y fracaso escolar, en un grupo de alumnos de Educación Secundaria Obligatoria pertenecientes a un Colegio Público Rural (Almería, España). Método. Ante tal situación, un grupo de profesores del centro junto al Equipo de Orientación Educativa, decidimos poner en marcha un proceso de investigación-acción, a través del cual aplicamos y evaluamos el Programa MATEL, cuya propuesta es conseguir eficacia lectora en los alumnos implicados a través de la práctica de una serie de estrategias que conducen a la mejora de la comprensión y la velocidad lectoras. Resultados. Comprobamos que la comprensión y la velocidad están asociadas a la eficacia lectora, no produciéndose tal asociación entre velocidad y comprensión lectoras. Las diferen-cias de medias entre las mediciones efectuadas constatan un efecto del tratamiento en la variabilidad de los resultados (velocidad, comprensión y efectividad). Discusión. Los resultados mostraron, tras la aplicación del Programa durante un curso esco-lar, que la instrucción fue efectiva de manera diferencial, ya que por una parte los alumnos consiguieron mejorar significativamente su eficacia lectora, y por otra, aumentar también sig-nificativamente su velocidad lectora. En el caso de la comprensión lectora, aunque se produjo un aumento significativo en la mayoría de los momentos de la investigación, bajó en el mo-mento final.