bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ecological Momentary Assessments and Interventions in Alzheimer’s Caregiving
Authors: Lazzari Carlo 
Published: July 2018

Background:
Caregivers of persons with Alzheimer’s Disease (AD) often experience feelings
of lack of support and information from specialists when operating in real scenarios, inclusive of old-age
psychiatric wards, care homes, community, and patient’s home.

Objective:
AD caregivers can provide narrative about what issues need to be addressed in Ecological
Momentary Assessment (EMA) to capture real-time and real-scenario needs in AD caregiving, and Ecological
Momentary Interventions (EMI) as online e-learning to assist in areas of concerns.

Method:
Twelve focus group discussions took place with AD caregivers for a total of 62 people interviewed.
Once major themes in surveys and learning were identified by using discourse analysis, AD
caregivers expressed the likelihood that these themes (where 0 meant “nil” and 1 meant “completely”)
would address their focal needs in caregiving and topics in learning. Z scores for proportions and
Cohen’s d effect size were calculated for each item reporting the averaged scores.

Results:
AD caregivers indicated that the major areas of concern that could benefit from an EMA/EMI
online platform were: support (d=3.08), collaboration (d=1.85), medication review (d=1.21), dealing
with grief and mourning, and time (d=0.97). Moreover, they identified personal resources available to
provide help to colleagues: support (d=1.34), information (d=0.97), collaboration (d=2.06), hospital admission
(d=3.08), and hospital discharge (d=5.50).

Conclusion:
Focus groups and narratives can be the initial stage in creating a dedicated AD app supporting
EMA/EMI in AD care.
Oral Acute and Repeated-Doses Toxicity Study of Valepotriates from Valeriana glechomifolia (Meyer) in Mice
Authors: de Almeida Tielle Moraes , von Poser Gilsane Lino , Müller Liz Girardi , Pereira Paula Reis , Cassel Eduardo , Vargas Rubem Mario Figueiro , da Silva Nunes Nilson Junior , Driemeier David , Dallegrave Eliane , de Faria Valle Stella , Kuze Rates Stela Maris 
Published: July 2018

Background:Species of Valeriana show sedative, hypnotic, anxiolytic, antidepressant and anti-inflammatory properties, which are associated with valepotriates. However, data about toxicity and safety of these compounds are still limited. The aim of this study was to investigate the toxicity of a valepotriate-enriched fraction (VAL) from Valeriana glechomifolia Meyer based on the Organization for Economic Cooperation and Development (OECD) guidelines 423 and 407.Methods:In the acute study, CF1 mice were treated with a single dose of VAL (2000 mg/kg, p.o.) and observed for 14 days. In the repeated dose study, CF1 mice received single daily doses of VAL (30, 150 or 300 mg/kg, p.o.) or vehicle for 28 days. These doses were chosen based on previous results by our group and according to Guideline 407- OECD.Results:The acute study allowed to classify VAL in the hazard category 5. The repeat-dose study has shown that VAL 300 mg/kg delayed weight gain and reduced food consumption in the first week, probably due to transient sedative effects. The other doses had no effect on animals’ ponderal evolution. At the end of the treatment, all groups had equal body weight and food consumption. None of the doses altered any behavioral, urinary, biochemical, hematological, anatomic or histological parameters.Conclusion:A valepotriate-enriched fraction from Valeriana glechomifolia presents relatively low oral acute toxicity and does not induce evident toxicity after oral repeated treatment (at least up to 300 mg/kg) in mice.<P&gt;
Folate Nutritional Status among Psoriasis Patients not Exposed to Antifolate Drug
Authors: Tomita Luciana Y. , da Costa Andréia C. , Andreoni Solange , Oyafuso Luiza K.M. , D’Almeida Vânia , Fonseca Fernando L.A. , Rocha Ana C.L. , Kobata Clarice 
Published: July 2018

Background:Folic acid fortification program has been established to prevent tube defects. However, concern has been raised among patients using anti-folate drug, i.e. psoriatic patients, a common, chronic, autoimmune inflammatory skin disease associated with obesity and smoking.Objective:To investigate dietary and circulating folate, vitamin B12 (B12) and homocysteine (hcy) in psoriatic subjects exposed to the national mandatory folic acid fortification program.Methods:Cross-sectional study using the Food Frequency Questionnaire, plasma folate, B12, hcy and psoriasis severity using the Psoriasis Area and Severity Index score. Median, interquartile ranges (IQRs) and linear regression models were conducted to investigate factors associated with plasma folate, B12 and hcy.Results:82 (73%) mild psoriasis, 18 (16%) moderate and 12 (11%) severe psoriasis. 58% female, 61% non-white, 31% former smokers, and 20% current smokers. Median (IQRs) were 51 (40, 60) years. Only 32% reached the Estimated Average Requirement of folate intake. Folate and B12 deficiencies were observed in 9% and 6% of the blood sample respectively, but hyperhomocysteinaemia in 21%. Severity of psoriasis was negatively correlated with folate and B12 concentrations. In a multiple linear regression model, folate intake contributed positively to 14% of serum folate, and negative predictors were psoriasis severity, smoking habits and saturated fatty acid explaining 29% of circulating folate.Conclusion:Only one third reached dietary intake of folate, but deficiencies of folate and B12 were low. Psoriasis severity was negatively correlated with circulating folate and B12. Stopping smoking and a folate rich diet may be important targets for managing psoriasis.
ÖĞRETMENLERİN OKUL YAŞAM KALİTESİ ALGILARI İLE MESLEKİ MOTİVASYON DÜZEYLERİNİN İNCELENMESİ
Authors: Sarı Mediha , Canoğulları Emre , Yıldız Emine 
Published: July 2018

Bu çalışmanın amacı
öğretmenlerin okullarındaki yaşam kalitesine ilişkin algıları ile mesleki
motivasyon düzeylerinin incelenmesidir. Çalışmada ele alınan bu iki değişken
öğretmenlerin cinsiyeti, kıdemi ve mezun olduğu okul türü bakımından
incelenmiştir. Daha sonra öğretmenlerin okul yaşam kalitesi algıları ile
mesleki motivasyon düzeyleri arasındaki istatistiksel ilişkiler
irdelenmiştir.

Katılımcılar Adana il
merkezinde yer alan beş ilkokulda görev yapan 134 öğretmendir. Okul Yaşam
Kalitesi Ölçeği ile İlkokul Öğretmeni Motivasyon Ölçeği kullanılarak toplanan
verilerin analizinde betimsel istatistikler incelenmiş, t-testi, tek yönlü
varyans, korelasyon ve regresyon analizleri yapılmıştır. Analizler sonucunda,
öğretmenlerin okul yaşam kalitesi algılarının orta düzeyde, motivasyon
düzeylerinin ise ortanın hafif üzerinde olduğu belirlenmiştir. Çalışmada cinsiyete
göre anlamlı fark bulunmamışken, öğretmenlerin okul yaşam kalitesi algılarında
kıdeme göre anlamlı farklar bulunmuştur. Ayrıca öğretmenlerin okul yaşam
kalitesi algıları ile mesleki motivasyon düzeyleri arasında pozitif yönde
anlamlı ilişkiler bulunduğu ve OYKÖ puanlarının öğretmen motivasyonunu anlamlı
bir şekilde yordadığı belirlenmiştir
HUBUNGAN STATUS GIZI DENGAN PNEUMONIA BALITA DI PUSKESMAS UMBAN SARI PEKANBARU TAHUN 2016
Authors: Piliang Nelfi Sarlis , Filda Mutya 
Published: July 2018

<p><em>According to the health ministry Indonesia, pneumonia is an cause death to two infants after diarrhea. Pneumonia is an acute infection of the respiratory system that has symptoms cough, fever and shortness of breath</em>. <em>This</em><em> research aims to determine the relationship of nutritional status with the incidence of pneumonia in toddlers in health center Umban Sari Pekanbaru year 2016. </em><em>This type of research is quantitative with correlation analysis. Research design cross sectional. Population in this research is population of all under five working area of Puskesmas Umban Sari Pekanbaru year 2016 in November to December. Sampling technique sampel use Simple Random Sampling with the number of samples 187 people. It is hoped that this research can beused as input for health workers, especially midwives in improving health service for children, by way of providing education to mothers who have children under five about the provision of nutritional in take to their children and identification risk factor that occur when a poorly metabolized intake leads to infection.</em></p><p> </p><p>Menurut Kementerian Kesehatan, <em>pneumonia </em>merupakan penyebab kematian kedua balita setelah diare. Pneumonia merupakan infeksi akut pada sistem pernafasan yang mempunyai gejala batuk, demam dan sesak nafas. Penelitian ini bertujuan untuk mengetahui hubungan status gizi dengan kejadian <em>pneumonia </em>pada balita di Puskesmas Umban Sari Pekanbaru Tahun 2016. Jenis penelitian ini adalah kuantitatif dengan analisis korelasi. Desain penelitian <em>cross sectional</em>. Populasi dalam penelitian ini adalah populasi seluruh balita di wilayah Kerja Puskesmas Umban Sari Pekanbaru Tahun 2016 pada bulan November sampai Desember. Teknik pengambilan sampel menggunakan <em>Simple Random Sampling </em>dengan jumlah sampel 187 orang. Adapun hasil <em>bivariat </em>dari uji <em>Chi-square </em>menunjukkan hasil bahwa terdapat hubungan yang bermakna antara status gizi dengan kejadian <em>pneumonia </em>pada balita. Diharapkan penelitian ini dapat dijadikan masukkan bagi tenaga kesehatan khususnya bidan dalam meningkatkan pelayanan kesehatan bagi balita.</p>
FAKTOR RISIKO UTAMA MATERNAL PENYEBAB ABORTUS DI PUSKESMAS KECAMATAN IV KOTO KABUPATEN AGAM
Authors: Putri Lydia Mardison 
Published: July 2018

<p><em>The purpose of this study to determine the main factors abortion in area of Agam Regency with 119 pregnant mothers in 2016 by using cross sectional approach and logistic binary regression test analysis. The results found that 14.3% of mothers encountered abortion. There were six variables that had significant relationship to major risk factors; mother’s education level (OR 6.161), mother’s occupation (OR 8,000), family economic status (OR 0.138), mother’s psychology (OR 5,497), husband’s role (OR 0, 95) and Ante Natal Care (ANC) quality (OR 10,714). Meanwhile mother’s age and parity were considered insignificant. The result of logistic regression test found that ANC quality p = 0,021, 95% CI, Exp B 6.871 was the major risk factor of abortion and the confounding factors were mother’s education level, family economic status and husband role due to change of OR&gt; 10% in Agam regency in 2016. Concultion is the implementation quality of ANC can decrease abortion. Researcher expects that the Head of Health Department do coaching health workers to improve the quality of integrated ANC.</em></p><p><em><br /></em></p><p><em><br /></em>Tujuan penelitian ini untuk mengetahui faktor utama abortus di wilayah kabupaten Agam kepada 119 ibu hamil tahun 2016 dengan pendekatan <em>cross sectional</em> dan menggunakan analisis uji <em>regresi logistic binary</em>. Hasil penelitian ditemukan 14,3% ibu mengalami abortus, variabel tingkat pendidikan ibu (OR 6.161), pekerjaan ibu (OR 8.000), status ekonomi keluarga ibu (OR 0.138), kondisi psikologis ibu (OR 5,497), peran suami (OR 0,95) dan kualitas Ante Natal Care (ANC) (OR 10,714)terdapat hubungan yang bermakna sebagai faktor risiko abortus. Dan variabelusia ibu, paritas tidak menjadi faktor risiko penyebab abortus. Hasil uji <em>regersi logistic</em> ditemukan kualitas ANC p=0,021, CI 95%, Exp B 6.871 adalah faktor risiko utama abortus dan variabel tingkat pendidikan ibu, status ekonomi keluarga dan peran suami menjadi faktor <em>confounding </em>karena perubahan OR&gt; 10% di Kecamatan IV Koto tahun 2016. Kesimpulan pelaksanaan ANC berkualitas dapat menurunkan kejadian abortus, Harapan peneliti kepada dinas kesehatan untuk melakukan pembinaan sumber daya kesehatan untuk meningkatkankan kualitas ANC terpadu.</p>
REITERATIONS IN 'PRIANGAN SI JELITA' AND THEIR IMPLICATIONS TOWARD INDONESIAN LANGUAGE LEARNING AT SECONDARY SCHOOLS (REITERASI DALAM 'PRIANGAN SI JELITA' DAN IMPLIKASINYA PADA PEMBELAJARAN BAHASA INDONESIA DI SMP)
Authors: Muhyidin Asep 
Published: July 2018

This research studied the use of reiterationÂ in che ollection of poems Priangan Si Jelita. The object of this research is reiteration which consist of repetition, synonymy, metonymy, and hyponymy. This research used both theoretical and methodological approaches. The former was discourse analysis whereas the latter was qualitative-descriptive approach. The result of analysis shows that the strength and beauty of the forms and meanings of the poems in Priangan Si Jelita are mostly built by the lexical cohesive elements within, particularly reiteration covering repetition, synonymy, metonymy, and hyponymy. The most dominant reiteration in the poems is repetition. This research has an implication toward Indonesian language learning for class IXÂ students of junior high school in the material of paraphrasing poems in accordance with the structure and principles of texts in written form
Reflexiones acerca de la metodología cualitativa para el estudio de las organizaciones
Authors: Fassio Adriana 
Published: July 2018

En este artículo se aborda la discusión sobre la complementariedad/ antagonismo de las perspectivas cualitativas y cuantitativas, a partir de lo cual se profundiza sobre algunas características de la metodología y técnicas cualitativas y su puesta en juego para el diagnóstico organizacional.Se reflexiona sobre los componentes y secuencia de las decisiones que se toman a lo largo de una investigación organizacional desde la perspectiva cualitativa, así como sobre los alcances y dificultades que se enfrentan.
Actitud hacia la marca ante un evento inesperado: Rol del pensamiento holístico y analítico
Authors: López Hurtado Jonnathan 
Published: July 2018

Este trabajo intenta comprender el rol del pensamiento holístico y analítico como moderadores de la actitud hacia la marca adoptada por un individuo ante un suceso inesperado que involucra la reasignación de recursos en alternativas diferentes a las inicialmente consideradas por el decisor.Para tal fin, se abordan las teorías que componen este escenario y los efectos producidos ante dicha situación. Adicionalmente, el presente artículo propone un marco integrado de análisis compuesto por seis hipótesis, las cuales deben ser llevadas a una fase de trabajo de campo que confirme o modifique lo que hasta ahora corresponde a nociones de carácter predictivo.
Metodologia estatística para validação de analistas em ensaios microbiológicos quantitativos
Authors: TAKADA Veruska Norie , OLIVEIRA Anderson Castro Soares de , PASCOA Marcelino Alves Rosa de , MARTINS Marcelo Aparecido 
Published: July 2018

Todo alimento é um excelente meio de cultura para o desenvolvimento de microrganismos. A preocupação com a contaminação e proliferação destes em alimentos com relação à saúde pública é crescente no mundo, implicando em desenvolvimento de métodos de controle em empresas alimentícias. Por esta razão tem-se tornado frequente a prática de se analisar os alimentos para o consumo e a verificação da existência de bactérias responsáveis por intoxicação e infecção por alimentos. Deste modo, Controle de Qualidade é a forma geralmente utilizada para descrever todas as medidas tomadas que irão garantir a qualidade das práticas realizadas no laboratório. Neste contexto este trabalho tem como objetivo estabelecer um protocolo estatístico de validação de analistas, como parte de um sistema de controle de qualidade para análises microbiológicas quantitativas de alimentos.Para tanto foram realizadas simulações de qualificação dos analistas considerando um delineamento inteiramente casualizado e posterior análise dos dados por meio dos testes ANOVA e ANDEV. Os resultados mostram que a ANDEV é melhor que a ANOVA na detecção da variabilidade entre os analistas, tendo apresentado uma taxa menor de erro do tipo I, além de possuir um poder maior. Desta forma a ANDEV necessita uma quantidade menor de repetições, se adequando melhor à rotina e a realidade entre custo-benefício dos laboratórios.
Investigating Fast Mapping task components: no evidence for the role of semantic referent nor semantic inference in healthy adults
Authors: Cooper Elisa , Greve Andrea , Henson Richard 
Published: July 2018

Fast Mapping (FM) is an incidental learning process that is hypothesised to allow rapid, cortical-based memory formation, independent of the normal, hippocampally-dependent episodic memory system. It is believed to underlie the rapid vocabulary learning in infants that occurs separately from intentional memorisation strategies. Interest in adult FM learningwas stimulated by a report in which adults with amnesia following hippocampal damage showed a normal ability to learn new object-name associations after an incidental FM task,despite their impaired memory under a conventional intentional memorisation task. This remarkable finding has important implications for memory rehabilitation, and has led to a number of neuropsychological and neuroimaging studies in other patients and controls. Given this growing interest in adult FM, we conducted four behavioural experiments with healthy adults (N=24 young or older adults in Experiment 1-3 using within-participantdesigns; N=195 young adults in Experiment 4 using a between-participant design) that attempted to dissect which component(s) of the FM task are important for memory. Two key components of the FM task have been claimed to support FM learning: i) provision of a known semantic referent and ii) requirement that the new association be inferred. Experiment 1 provided no evidence that removing the semantic referent impaired memory performance, while Experiment 2 provided no evidence that removing the semantic inference impaired performance. Experiment 3 was a replication of Experiment 2 with older participants, basedon the hypothesis (from studies of amnesic individuals) that FM would be more effective following the hippocampal atrophy typical of increasing age, but again found no evidence that semantic inference is beneficial. Given potential concerns about contamination between tasks when each participant performed multiple variants of the FM task, we ran a final between-participant design in which each participant only ever did one condition. Despite 80% power and despite being able to detect better memory following intentional memorisation in the explicit encoding (EE) control condition than in each of the FMconditions, we again found no evidence of differences between any FM conditions. We conclude that there is no evidence that the components hypothesized to be critical for FM are relevant to healthy adults.
Factors contributing the outcome of Schizophrenia in developing and developed countries: A brief review
Authors: Rahman Mahmudur 
Published: July 2018

AbstractAccording to WHO,schizophrenia is a severe form of mental illness affecting about 7 per thousandof the adult population, mostly in the age group 15-35 years. Though theincidence is low (3-10,000), the prevalence is high due to chronicity. Schizophrenia is occurring in both developingand developed countries.The remission rate is higher in developing countries compared to the developedones. There are some compelling factors that may influence the outcome ofschizophrenia includes gender, employment, marital status, family support,illness myths, family burden, duration of untreated psychosis etc. In this review we have discussed the epidemiology,pathophysiology, diagnosis, treatment and finally the factors that influencethe outcome of schizophrenia in developing and developed countries. Mahmudur Rahman B. Pharm. (Hons.), M. Pharm (Thesis), M.Sc. in Pharm (Thesis), RegPharmBDPhD StudentSouthern Cross Plant Science | Southern Cross UniversityLismore, NSW 2480, Australiahttp://scu.edu.au/scps/index.php/166Assistant Professor (on leave),Department of Pharmacy. Northern University Bangladesh. 24, Mirpur Road, Globe Centre, Dhaka-1205, Bangladesh.http://www.nub.ac.bd/pims/faculty-member/mr28vw4a/mr.-mahmudur-rahmanURL: https://www.researchgate.net/profile/Mahmudur_Rahman3?hl=enhttps://scholar.google.com./citations?hl=en&user=17qL1a8AAAAJCallSend SMSCall from mobileAdd to SkypeYou'll need Skype Credit
Pitting Corrosion on a Water Pipe of the Grade 1.4301
Authors: Strobl S. , Linhardt P. , Ball G. , Haubner R. 
Published: July 2018

Abstract
Pipes made of stainless steel in the drinking water supply system showed pitting corrosion in the heat-affected zone (HAZ) of the welded joints. This was very surprising considering the chemical composition of the fresh water and the fact that no microbiologically influenced corrosion (MIC) had been found.
Testing for pitting corrosion showed no increased sensitivity of the HAZ. The Electrochemical Potentiodynamic Reactivation test (EPR test), however, was positive for the tube interior and only within the HAZ. Metallographic examinations were carried out to clarify if sensitization or intergranular attack, a type of corrosion, were the cause.
The holes showed an irregular propagation which can be explained by segregation lines in the steel. It is noticeable that the holes preferably propagate in the mid-thickness region of the steel sheet. The metallographic samples showed no preferred corrosive attack along the grain boundaries (intergranular attack) and also no sensitization of the steel.
Technique: open lumbar decompression and fusion with the Excelsius GPS robot
Authors: Zygourakis Corinna C. , Ahmed A. Karim , Kalb Samuel , Zhu Alex M. , Bydon Ali , Crawford Neil R. , Theodore Nicholas 
Published: July 2018

The Excelsius GPS (Globus Medical, Inc.) was approved by the FDA in 2017. This novel robot allows for real-time intraoperative imaging, registration, and direct screw insertion through a rigid external arm—without the need for interspinous clamps or K-wires. The authors present one of the first operative cases utilizing the Excelsius GPS robotic system in spinal surgery. A 75-year-old man presented with severe lower back pain and left leg radiculopathy. He had previously undergone 3 decompressive surgeries from L3 to L5, with evidence of instability and loss of sagittal balance. Robotic assistance was utilized to perform a revision decompression with instrumented fusion from L3 to S1. The usage of robotic assistance in spinal surgery may be an invaluable resource in minimally invasive cases, minimizing the need for fluoroscopy, or in those with abnormal anatomical landmarks.The video can be found here: https://youtu.be/yVI-sJWf9Iw.
Recent Advances in the Discovery and Delivery of TLR7/8 Agonists as Vaccine Adjuvants
Authors: Dowling David J 
Published: July 2018

Abstract
The need for new adjuvants is absolutely cardinal to the development of new vaccines and to further optimizing current immunization approaches. However, only a few classes of adjuvants are presently incorporated in vaccines approved for human use. Recent advances in the discovery and delivery of TLR agonists as vaccine adjuvants have begun to open up a new toolbox for vaccinologists. At the forefront of this movement is the use of synthetic small molecule TLR7/8 agonist–based adjuvants. In this review, we emphasize the importance of vaccine formulation science in driving recent developments in TLR7/8 adjuvanticity, summarize some of the most current and notable studies in this field, and discuss desirable attributes of next generation TLR7/8 adjuvants for use in enhancing vaccine responses in vulnerable populations, such as the very young. Finally, we explore advances that may further edge the development of TLR7/8 adjuvant–based vaccine formulations toward clinical human evaluation.