bluuebunny/crossref_metadata_2025_split huggingface dataset:
CLASP mediates microtubule repair by promoting tubulin incorporation into damaged lattices
Authors: Aher Amol , Rai Dipti , Schaedel Laura , Gaillard Jeremie , John Karin , Blanchoin Laurent , Thery Manuel , Akhmanova Anna 
Published: October 2019

SummaryMicrotubule network plays a key role in cell division, motility and intracellular trafficking. Microtubule lattices are generally regarded as stable structures that undergo turnover through dynamic instability of their ends [1]. However, recent evidence suggests that microtubules also exchange tubulin dimers at the sites of lattice defects, which can either be induced by mechanical stress or occur spontaneously during polymerization [2–4]. Tubulin incorporation can restore microtubule integrity; moreover, “islands” of freshly incorporated GTP-tubulin can inhibit microtubule disassembly and promote rescues [3–7]. Microtubule repair occurs in vitro in the presence of tubulin alone [2–4, 8]. However, in cells, it is likely to be regulated by specific factors, the nature of which is currently unknown. CLASP is an interesting candidate for microtubule repair, because it induces microtubule nucleation, stimulates rescue and suppresses catastrophes by stabilizing incomplete growing plus ends with lagging protofilaments and promoting their conversion into complete ones [9–16]. Here, we used in vitro reconstitution assays combined with laser microsurgery and microfluidics to show that CLASP2α indeed stimulates microtubule lattice repair. CLASP2α promoted tubulin incorporation into damaged lattice sites thereby restoring microtubule integrity. Furthermore, it induced the formation of complete tubes from partial protofilament assemblies and inhibited microtubule softening caused by hydrodynamic flow-induced bending. A single CLASP2α domain, TOG2, which suppresses catastrophes when tethered to microtubules, was sufficient to stimulate microtubule repair, indicating that catastrophe suppression and lattice repair are mechanistically similar. Our results suggest that the cellular machinery controlling microtubule nucleation and growth can also help to maintain microtubule integrity.
Application of formal methods to modelling and analysis aspects of business process reengineering
Authors: Haseeb Junaid , Ahmad Naveed , Malik Saif U.R. , Anjum Adeel 
Published: October 2019

Purpose
Business process (BP) reengineering is defined as reinventing BPs either structurally or technically to achieve dramatic improvements in performance. In any business process reengineering (BPR) project, process modeling is used to reason about problems found in existing (as-is) process and helps to design target (to-be) process. BP model notation is a widely accepted standard for process modeling. “Expressiveness” and “missing formal semantics” are two problems reported to its modeling practices. In existing studies, solutions to these problems are also proposed but still have certain limitations. The paper aims to discuss this issue.

Design/methodology/approach
In proposed methodology, a meta-model is formally defined that is composed of commonly used modeling elements and their well-formedness rules to check for syntactic and structural correctness of process models. Proposed solution also check semantics of process models and allows to compare as-is and to-be process models for gap identification which is another important aspect of BPR. To achieve the first goal, Z specification is used to provide formal specifications of modeling constructs and their rules and Z3 (an SMT solver) is used for comparisons and verifying properties.

Findings
Proposed method addresses both “expressiveness” and “missing formal semantics” of BPR models. The results of its evaluation clearly indicate that using formally specified meta-model, BPR model is syntactically and structurally correct. Moreover, formal modeling of BPs in Z3 helped to compare processes and to check control flow properties.

Research limitations/implications
Although the proposed method is tested on an example that is widely used in BPR literature, the example is only covering modeling elements which are part of the proposed subset and are reported in literature as frequently used modeling elements. A separate detailed study is required to test it on more complex systems.

Practical implications
Specifying process models using Z specification and Z3 solver requires certain expertise.

Originality/value
The proposed method adds value to BPR body of knowledge as it proposes a method to ensure structural and syntactic correctness of models, highlighting the importance of verifying run time properties and providing a direction toward comparing process models for gap analysis.
Cross-cultural professional experiences of female expatriates
Authors: France Tami , Booysen Lize , Baron Carol 
Published: October 2019

Purpose
In this world of global interconnectedness, women continue to develop cross-cultural careers and their experiences impact global scholarship and practice. The purpose of this paper is to explore the relationships, resources and characteristics that support female expatriate success, with specific focus on the role of mentor/coach relationships. The sample included 102 women from the USA, Canada, Australia and the UK working or formerly working in Mainland China, Hong Kong, Macau or Taiwan.

Design/methodology/approach
This three phase sequential mixed-methods exploratory research study included 10 one-on-one semi-structured interviews, 102 survey respondents and 3 facilitated focus groups attended by nine professional women.

Findings
This research offers evidence that resiliency-based characteristics must be cultivated and developed to support expatriate cross-cultural success. These characteristics can be cultivated through relying on multiple relationships, such as mentors, coaches, host country liaisons, expatriate colleagues, friends and family as well as by supporting and mentoring others. These characteristics can also be developed through specific cultural experiences, knowledge and skill building resources, as well as developing an informed view of self and identity clarity through reflective activities.

Originality/value
Based on the overall findings, a cross-cultural professional success model was designed and implications for scholarship, organizational effectiveness and cross-cultural leadership practice are presented.
Do management earnings forecasts fully reflect information in past earnings changes?
Authors: Gong Guojin , Li Yue , Zhou Ling 
Published: October 2019

Purpose
It has been widely documented that investors and analysts underreact to information in past earnings changes, a fundamental performance indicator. The purpose of this paper is to examine whether managers’ voluntary disclosure efficiently incorporates information in past earnings changes, whether analysts recognize and fully anticipate the potential inefficiency in management forecasts and whether managers’ potential forecasting inefficiency entirely results from intentional disclosure strategies or at least partly reflects managers’ unintentional information processing biases.

Design/methodology/approach
Archival data were used to empirically test the relation between management earnings forecast errors and past earnings changes.

Findings
Results show that managers underreact to past earnings changes when projecting future earnings and analysts recognize, but fail to fully anticipate, the predictable bias associated with past earnings changes in management forecasts. Moreover, analysts appear to underreact more to past earnings changes when management forecasts exhibit greater underestimation of earnings change persistence. Further analyses suggest that the underestimation of earnings change persistence is at least partly attributable to managers’ unintentional information processing bias.

Originality/value
This study contributes to the voluntary disclosure literature by demonstrating the limitation in the informational value of management forecasts. The findings indicate that the effectiveness of voluntary disclosure in mitigating market mispricing is inherently limited by the inefficiency in management forecasts. This study can help market participants to better use management forecasts to form more accurate earnings expectations. Moreover, our evidence suggests a managerial information processing bias with respect to past earnings changes, which may affect managers' operational, investment or financing decisions.
Optimization of wear parameters of Mg-(5.6Ti+3Al)-2.5B4C composite
Authors: S. Sathish , V. Anandakrishnan , Manoj Gupta 
Published: October 2019

Purpose
The purpose of this study is to analyse and optimize the wear parameters of magnesium metal-metal composite. Materials with lesser weight attract both the researcher and industrialists, as it exhibits the performance improvement in the automotive and aerospace industries. The enrichment of mechanical and tribological properties of the existing magnesium focussed the development of new metal–metal composite.

Design/methodology/approach
Metal–metal composite with magnesium matrix was synthesized through the disintegrated melt deposition technique with the addition of titanium, aluminium and boron carbide particles. The wear performance of the composite was experimented with the dry sliding wear test by considering load, sliding velocity and sliding distance.

Findings
The wear rate of the composite is analysed statistically, and the significance of wear parameters on the wear performance of metal–metal composite is observed. The worn pin surface and the wear debris collected during the wear experiments were exposed to the microscopy analysis to seize the dominating wear mechanisms.

Originality/value
The wear performance of the developed magnesium composite was analysed and discussed in detail with the support of scientific evidence, i.e. worn surface and debris analysis express the wear mechanisms.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-08-2019-0326/
Spatio-temporal variations in agricultural diversification in India
Authors: Anwer Md Ejaz , Sahoo Bimal Kishore , Mohapatra Simantini 
Published: October 2019

PurposeAgriculture diversification acts as income enhancing as well as distress mitigating strategy. India has witnessed rise in per-capita income which in turn has increased the demand for food particularly high-valued food items but agricultural production has failed to keep pace with the growing demand. The purpose of this paper is to examine spatio-temporal variations in agricultural diversification (AD) in India. Second, the authors try to identify the determinants of AD. Third, the authors examine the convergence hypothesis with reference to agriculture diversification across Indian states.Design/methodology/approachThe study is based on the panel data constituting 20 major states of India during 1990–1991 to 2013–2014. It uses Simpson Diversification Index to measure AD. The heteroskedasticity-corrected panel regression model is applied to find out the determinants of AD. The fixed-effects model is used to examineβ-convergence in AD across the sample states. Alternative time series models are applied to examineσ-convergence in AD.FindingsThe rising per-capita income and urbanization are driving dietary diversity towards high-valued crops and providing ample opportunity for AD. But poor and inadequate cold storage facility and rising cost of cultivation are posing major hindrance to it. Small land holding and road length have negatively influenced AD which is contrary to the traditional wisdom. The study found divergence in diversification and rising inequality in diversification.Research limitations/implicationsThe study is based on secondary data. A primary study to complement this could have been better. It is only based on one country.Social implicationsFood inflation has serious adverse effect on the society at large. It is necessary to promote AD for controlling food price inflation. Minimum support price provided by the government should be extended to all crops; otherwise, it will fuel inflation. Given the fact fragmentation of land holding is adversely affecting AD, community based farming and consolidation of farm land should be the way forward to improve farmers’ income as well as reduce risk.Originality/valueTo best of the authors’ study, this is the first study that examines determinants of AD and convergence in AD during the high growth period of India.
International expansion for knowledge acquisition or knowledge acquisition for international expansion?
Authors: Kogut Clarice Secches , Cotta de Mello Renato Dourado , Rocha Angela da 
Published: October 2019

PurposeStarting from the knowledge-based view as a theoretical perspective, this study aims to examine how an emerging market multinational enterprise (EMMNE) engages in reverse knowledge transfer (RKT) processes and how such processes are managed by headquarters. Therefore, this paper captures the perspective of top management concerning RKT and the processes used to create, transfer and integrate knowledge.Design/methodology/approachThe study uses a longitudinal design based on the case method of investigation. The case selected for the study was a Brazilian company theoretically sampled for being a domestically, regionally and globally important, information-rich company that operates in an industry in which technology plays a crucial role. The company was also selected for having had asset-seeking motives in at least some of its foreign market entries and for having successfully absorbed foreign-acquired capabilities.FindingsThe study provides counterfactual evidence to the springboard perspective, considering timing and speed of the internationalization and catch-up processes and the size of acquisitions. The study also highlights differences to other emerging market multinational enterprises, concerning the internationalization trajectory and catch-up moves, and to traditional MNEs, regarding RKT challenges and practices.Research limitations/implicationsThe main limitations of the study relate to the case study method, which does not allow for statistical generalization, although it does support analytical generalization.Originality/valueThe study contributes to the literature by shedding light on the process by which a Latin American multinational firm developed technological capabilities to compete globally, focusing on the symbiotic, self-nurturing relationship between internationalization processes and technology acquisition and integration processes. Moreover, the work provides novel theoretical insights regarding timing, location, size and execution of the RKT activities. Finally, the paper contributes to the understanding of the relational aspects of the RKT process by focusing on building human relationships as the major force behind knowledge integration and examining the resistance of the acquired companies from developed markets to adopt the parent company’s best practices, or to contribute to its integrated knowledge, when the parent company is an EMMNE.
What citation patterns reveal about reading research and practice in academic libraries
Authors: Dali Keren , McNiff Lindsay 
Published: October 2019

Purpose
At the turn of the twenty-first century, academic libraries revived their tradition of working with readers, which resulted in a surge of publications in this area. However, the nature and thematic coverage of these publications has not changed dramatically in the past 18 years, signaling little advancement in the reach and scope of this professional activity. This paper aims to address the following research problem: What do citation patterns reveal about reading research and practice in academic libraries and do they point to interdisciplinary research and the presence of an evidence base or do they carry a mark of an inward disciplinary orientation?

Design/methodology/approach
This is a qualitative exploratory study, also involving descriptive statistics, that uses bibliographic and citation analysis as a method.

Findings
The study discovers a disconnect between the diversity of interdisciplinary research cited in the published work on reading in academic libraries and the sameness of respective professional practices; it describes a relatively small community of reading researchers in academic libraries, emerging as leaders who can change the direction and scope of reading practices; and it highlights a preference of academic librarians for relying on interdisciplinary knowledge about reading over building on the readers’ advisory experience of public librarians.

Originality/value
Translating the incredible wealth of interdisciplinary reading knowledge possessed by academic librarians into practical applications promises to advance and diversify reading practices in academic libraries. One method that could aid in this effort is more intentional learning from the readers’ advisory practices of public librarians.
At the nexus of three kingdoms: the genome of the mycorrhizal fungus Gigaspora margarita provides insights into plant, endobacterial and fungal interactions
Authors: Venice Francesco , Ghignone Stefano , Salvioli di Fossalunga Alessandra , Amselem Joëlle , Novero Mara , Xianan Xie , Sędzielewska Toro Kinga , Morin Emmanuelle , Lipzen Anna , Grigoriev Igor V. , Henrissat Bernard , Martin Francis M. , Bonfante Paola 
Published: October 2019

SummaryAs members of the plant microbiota, arbuscular mycorrhizal fungi (AMF, Glomeromycotina) symbiotically colonize plant roots. AMF also possess their own microbiota, hosting some uncultivable endobacteria. Ongoing research has revealed the genetics underlying plant responses to colonization by AMF, but the fungal side of the relationship remains in the dark. Here, we sequenced the genome of Gigaspora margarita, a member of the Gigasporaceae in an early diverging group of the Glomeromycotina. In contrast to other AMF, G. margarita may host distinct endobacterial populations and possesses the largest fungal genome so far annotated (773.104 Mbp), with more than 64% transposable elements. Other unique traits of the G. margarita genome include the expansion of genes for inorganic phosphate metabolism, the presence of genes for production of secondary metabolites and a considerable number of potential horizontal gene transfer events. The sequencing of G. margarita genome reveals the importance of its immune system, shedding light on the evolutionary pathways that allowed early diverging fungi to interact with both plants and bacteria.
Variation in menopausal vasomotor symptoms outcomes in clinical trials: a systematic review
Authors: Iliodromiti S , Wang W , Lumsden MA , Hunter MS , Bell R , Mishra G , Hickey M 
Published: October 2019

BackgroundThere is substantial variation in how menopausal vasomotor symptoms are reported and measured among intervention studies. This has prevented meaningful comparisons between treatments and limited data synthesis.ObjectivesTo review systematically the outcome reporting and measures used to assess menopausal vasomotor symptoms from randomised controlled trials of treatments.Search strategyWe searched MEDLINE, Embase, and Cochrane Central Register of Controlled Trials from inception to May 2018.Selection criteriaRandomised controlled trials with a primary outcome of menopausal vasomotor symptoms in women and a sample size of at least 20 women per study arm.Data collection and analysisData about study characteristics, primary vasomotor‐related outcomes and methods of measuring them.Main resultsThe search identified 5591 studies, 214 of which were included. Forty‐nine different primary reported outcomes were identified for vasomotor symptoms and 16 different tools had been used to measure these outcomes. The most commonly reported outcomes were frequency (97/214), severity (116/214), and intensity (28/114) of vasomotor symptoms or a composite of these outcomes (68/214). There was little consistency in how the frequency and severity/intensity of vasomotor symptoms were defined.ConclusionsThere is substantial variation in how menopausal vasomotor symptoms have been reported and measured in treatment trials. Future studies should include standardised outcome measures which reflect the priorities of patients, clinicians, and researchers. This is most effectively achieved through the development of a Core Outcome Set. This systematic review is the first step towards development of a Core Outcome Set for menopausal vasomotor symptoms.Tweetable summaryMenopausal hot flushes and night sweats have been reported in 49 different ways in clinical research. A core outcome set is urgently required.
Petitioning and Petitioners to the Westminster Parliament, 1660–1788
Authors: Loft Philip 
Published: October 2019

AbstractNarratives of the mid‐18th‐century state as drifting towards oligarchy and closure have long been superseded by accounts stressing its responsiveness to outside interests and opinion. Participatory election rituals, crowd activity and the expansion of print media demonstrate that political activism was not limited to a narrow circle of elites, even after the passage of the 1716 Septennial Act. Additionally, as an institution after 1688 the Westminster parliament rendered itself useful to propertied society through its passage of greater amounts of legislation. However, while the strength of party and trajectory of electoral participation is well mapped, as are addresses to the crown, the petitioning of interest groups has had few systematic quantitative surveys. This article first sets out the chronology of petitioning to both houses of parliament from 1660 to 1788, demonstrating that petitioning was at its height before 1722, rather than rising to its greatest levels with the reform movements in the 1780s. Second, the article demonstrates the role of petitioning in expanding the political nation beyond the boundaries of parliamentary boroughs, and why, on occasion, petitioning involved women and illiterate men. Third, in order to emphasize the continuity in petitioning and its contribution to the formation of public opinion, the article compares the different roles that concurrent subscription practices envisaged for the public. Finally, the article argues that despite the rising tendency to cite numerical strength to arbitrate political divisions, petitioners continued to legitimise their voices on the basis of representing collections of reasons and interests rather than opinion.