bluuebunny/crossref_metadata_2025_split huggingface dataset:
Une lecture des Adages d’Erasme, entre bibliographie rêvée et bibliothèque idéale
Authors: Diu Isabelle 
Published: June 2019

Depuis leur première publication, en 1500, jusque leurs reprises, augmentations et adaptations, les Adages d’Érasme se présentent comme l’idéale bibliographie de lectures d’autorité et de traditions. Ces autorités et la manière dont elles sont mises en lumière par Érasme et ses imprimeurs constituent en effet une sorte de liste de lectures qu’il nous faut maintenant examiner. Érasme s’assigne en effet la tâche, même si elle n’est présentée qu’en creux, d’établir un véritable catalogue (catalogus ou recensio) des auteurs d’adages, anciens et modernes. Peut-on alors parler de la bibliographie comme la représentation textuelle d’une histoire littéraire qui se donne à lire ?AbstractAs of their first publication in 1500, up until their numerous reeditions, reimpressions, revisions, and augmentations, the Adages collected by Erasmus can be read as an ideal bibliography of authoritative sentences, anecdotes, and references. The reader is allowed to consider the Erasmian collection as a reading list for authorities but also for the art of publishing authorities. For Erasmus implicitly chooses to establish a catalogue (catalogus or recensio) of all ancient and modern authors of adages. Can we, then, consider bibliography as a performance, within the text, of literary history?
Logros y retos del Comité de Ética de la Investigación de la Facultad de Ciencias de La Salud ULS, Bogotá D.C
Authors: Rubio-Rincón Gina Sorel , Molina-Montoya Nancy Piedad , Jurado-Medina Sandra Patricia 
Published: June 2019

El comité de ética de la Facultad de Ciencias en la Salud (CEFCS) se constituyó con base en la normatividad nacional e internacional vigente en el año 2011. Es un organismo multidisciplinar, operativo, propositivo y consultivo que genera espacios de reflexión, análisis y discusión en torno a cuestiones éticas derivadas del desarrollo de investigaciones científicas como órgano asesor, de aval, seguimiento ético y de autorregulación. Objetivo: Presentar los logros y retos, del Comité de Ética de la Facultad de Ciencias de La Salud de La Universidad de La Salle, Bogotá. Materiales y métodos: Estudio basado en revisión documental de archivos y en las experiencias de los integrantes del comité. Resultados: Hasta el año 2017 se han evaluado 42 proyectos de investigación disciplinares en optometría, ciencias básicas, y salud ocupacional, con diseños descriptivos, analíticos y cualitativos. Logros: capacitación de la comunidad académica sobre la importancia del respeto a la dignidad y autonomía de los sujetos de investigación, sobre las buenas prácticas clínicas y el apoyo al desarrollo de asignaturas y la dinamización de la reflexión ética en investigación y publicaciones sobre el tema ético. Retos: aún se sigue observando resistencia por parte de los investigadores para responder a los requerimientos del Comité, siendo percibido en algunas ocasiones como un obstáculo para el desarrollo fluido de los proyectos; así mismo, existen dificultades en el seguimiento de los procesos de investigación y falta de autonomía económica del comité. Conclusiones: Este organismo ha venido teniendo visibilidad y reconocimiento ante la colectividad académica y científica con importantes logros y grandes desafíos para su futuro.
Vitamin D status and related factors among Korean stroke survivors: the Fourth and Fifth Korea National Health and Nutrition Examination Surveys
Authors: Lee Jung Soo , Kim Yeo Hyung 
Published: June 2019

Abstract
Background: The aim of this study was to investigate the vitamin D status and related factors in community-dwelling Korean stroke survivors.
Methods: Data of 23,872 individuals ≥20 years who participated in the Korea National Health and Nutrition Examination Surveys (KNHANES) were analyzed. Participants who had ever been diagnosed with stroke by a doctor were defined as stroke survivors (n = 431). The serum 25-hydroxyvitamin D (25(OH)D) level was measured by radioimmunoassay, and vitamin D deficiency was defined as 25(OH)D <20 ng/mL. The association between vitamin D and stroke status was analyzed using multivariable general linear models and logistic regression models adjusted for sociodemographic and clinical covariates.
Results: The adjusted mean 25(OH)D level of stroke survivors was significantly lower than that of nonstroke controls; however, after adjustment for SBP level and use of antihypertensive medication, the difference was no longer statistically significant. The burden of 25(OH)D deficiency was not higher in stroke survivors than in nonstroke controls (adjusted OR = 1.14; 95% CI, 0.81-1.62). Current smoking was independently associated with 25(OH)D deficiency among stroke survivors (adjusted OR = 3.17; 95% CI, 1.33-7.55).
Conclusions: These findings indicated that treatment of high blood pressure and smoking cessation may be important measures to control vitamin D levels in stroke survivors.
Factors Associated with Unsafe Induced Abortion among Women who attended Fitche Hospital, Oromia, Ethiopia: Cross-sectional study
Authors: Amhare Abebe Feyissa , Alemayehu Dereje Gobena , Bogale Alemtsehay Adam 
Published: June 2019

Abstract
Background

Unsafe induced abortion is one of the most medical and public health problems in developing countries including Ethiopia. Ethiopia has permitted abortion in specific legal circumstances when the conception of the fetus is caused by rape, incest, when continuation of pregnancy endangers the mother’s life. The aim of this study is to assess the magnitude and associated risk factors of unsafe induced abortion among women who received post abortion care service in Fitche Hospital.

Methods

Institutional based cross-sectional study was carried out among women who received post abortion care service at Fitche hospital from November 30, 2017 up to May 30, 2018. The data was collected using pre tested questionnaire and entered to EpiData version 3.1 software and analyzed using SPSS version 24. Descriptive statistics, multivariate logistic regression analysis and chi-square test were conducted.

Results

Three hundred and eight respondents (100% response rate) with mean age of 30 ± 9 years were participated in this study. From respondents, 45% had history of unsafe induced abortion and 27% of them reported the abortion was performed in house by traditional birth attendant. Single women were more likely practice unsafe induced abortion than widowed women [OR: 9.71; 95%CI (1.30 – 72.42)]. Women who had low monthly income [OR: 6.72; 95%CI (2.15 - 20.97)] and house wives [OR: 12.29; 95%CI (1.70 - 88.63)] were more likely practice unsafe induced abortion than counterparts. Failure of contraceptive methods, place of interference, method used for interference, a person who induced the abortion, a condition after procedure, and reasons to induce abortion were identified as association factors of unsafe induced abortion at P < 0.001.

Conclusion

The study assessed the magnitude and reported a significant association between unsafe induced abortion and socio-demographic factors, contraceptive practice, and abortion related items. These findings are positive enough to warrant a large-scale study to better understand the unsafe abortion vulnerability factors in Ethiopia.
Gene expression profile of human T cells following a single stimulation of peripheral blood mononuclear cells with anti-CD3 antibodies
Authors: Sousa Isabel Garcia , Simi Kelly Cristina Rodrigues , Almo Manuela Maragno do , Bezerra Maryani Andressa Gomes , Doose Gero , Raiol Taina , Stadler Peter F , Hoffmann Steve , Maranhão Andrea Queiroz , Brigido Marcelo M 
Published: June 2019

Abstract
Background: Anti-CD3 immunotherapy was initially approved for clinical use for renal transplantation rejection prevention. Subsequently, new generations of anti-CD3 antibodies have entered clinical trials for a broader spectrum of therapeutic applications, including cancer and autoimmune diseases. Despite their extensive use, little is known about the exact mechanism of these molecules, except that they are able to activate T cells, inducing an overall immunoregulatory and tolerogenic behavior. To better understand the effects of anti-CD3 antibodies on human T cells, PBMCs were stimulated, and then, we performed RNA-seq assays of enriched T cells to assess changes in their gene expression profiles. In this study, three different anti-CD3 antibodies were used for the stimulation: two recombinant antibody fragments, namely, a humanized and a chimeric FvFc molecule, and the prototype mouse mAb OKT3.
Results: Gene Ontology categories and individual immunoregulatory markers were compared, suggesting a similarity in modulated gene sets, mainly those for immunoregulatory and inflammatory terms. Upregulation of interleukin receptors, such as IL2RA, IL1R, IL12RB2, IL18R1, IL21R and IL23R, and of inhibitory molecules, such as FOXP3, CTLA4, TNFRSF18, LAG3 and PDCD1, were also observed, suggesting an inhibitory and exhausted phenotype.
Conclusions: In conclusion, we used a deep transcriptome sequencing method for comparing three anti-CD3 antibodies in terms of Gene Ontology enrichment and immunological marker expression. The present data showed that both recombinant antibodies induced a compatible expression profile, suggesting that they might be candidates for a closer evaluation with respect to their therapeutic value. Moreover, the proposed methodology is amenable to be more generally applied for molecular comparison of cell receptor dependent antibody therapy.
Partners in Crime: NGF and BDNF in Visceral Dysfunction
Authors: Coelho Ana , Oliveira Raquel , Antunes-Lopes Tiago , Cruz Célia Duarte 
Published: June 2019

:Neurotrophins (NTs), particularly Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF), have attracted increasing attention in the context of visceral function for some years. Here, we examined the current literature and presented a thorough review of the subject.:After initial studies linking of NGF to cystitis, it is now well-established that this neurotrophin (NT) is a key modulator of bladder pathologies, including Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC) and Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS. NGF is upregulated in bladder tissue and its blockade results in major improvements on urodynamic parameters and pain. Further studies expanded showed that NGF is also an intervenient in other visceral dysfunctions such as endometriosis and Irritable Bowel Syndrome (IBS).:More recently, BDNF was also shown to play an important role in the same visceral dysfunctions, suggesting that both NTs are determinant factors in visceral pathophysiological mechanisms. Manipulation of NGF and BDNF improves visceral function and reduce pain, suggesting that clinical modulation of these NTs may be important; however, much is still to be investigated before this step is taken.:Another active area of research is centered on urinary NGF and BDNF. Several studies show that both NTs can be found in the urine of patients with visceral dysfunction in much higher concentration than in healthy individuals, suggesting that they could be used as potential biomarkers. However, there are still technical difficulties to be overcome, including the lack of a large multicentre placebo-controlled studies to prove the relevance of urinary NTs as clinical biomarkers.
Application of Multinomial Regression Model to Identify Parameters Impacting Traffic Barrier Crash Severity
Authors: Rezapour Mahdi , Molan Amirarsalan Mehrara , Ksaibati Khaled 
Published: June 2019

Background:
Run Off The Road (ROTR) crashes are some of the most severe crashes that could occur on roadways. The main countermeasure that can be taken to address this type of crashe is traffic barrier installation. Although ROTR crashes can be mitigated significantly by traffic barriers, still traffic barrier crashes resulted in considerable amount of severe crashes. Besides, the types of traffic barriers, driver actions and performance play an important role in the severity of these crashes.

Methods:
This study was conducted by incorporating only traffic barrier crashes in Wyoming. Based on the literature review there are unique contributory factors in different crash types. Therefore, in addition to focusing on traffic barrier crashes, crashes were divided into two different highway classes: interstate and non-interstate highways.

Results:
The result of proportional odds assumption was an indication that multinomial logistic regression model is appropriate for both non-interstate and interstates crashes involved with traffic barriers. The results indicated that road surface conditions, age, driver restraint and negotiating a curve were some of the factors that impact the severity of traffic barrier crashes on non-interstate highways. On the other hand, the results of interstate barrier crashes indicated that besides types of barriers, driver condition, citation record, speed limit compliance were some of the factors that impacted the interstate traffic barrier crash severity.

Conclusion:
The results of this study would provide the policymakers with the directions to take appropriate countermeasures to alleviate the severity of traffic barrier crashes.
Hypertension and its Relation with Waist to Hip Ratio in Women Referred to Bojnurd Urban Health Centers in 2014
Authors: Lashkardoost Hossein , Hoseyni Fateme , Rabbani Elham , Moqadam Farzane Q , Hosseini Leila , Azizi Salimeh , Hamedi Andishe 
Published: June 2019

Introduction:
North Khorasan province has one of the highest rates of hypertension. One of the main causes of hypertension is obesity. Obesity is one of the most important public health problems around the world as a risk factor for non-communicable diseases. Since a similar study was not conducted in Bojnurd, we examined the relationship between waist to hip ratio with hypertension.

Methods:
The present cross-sectional study was conducted on women referring to Bojnurd health centers. To analyze the data, we used t-test, chi-square, multiple logistic regression and Pearson correlation in Stata 12 software.

Results:
In this cross-sectional study, the prevalence of systolic blood pressure was 14.78% and diastolic blood pressure was 15.65%. So waist to the hips showed the highest correlation with the changes in hypertension.

Conclusion:
There are significant relationships between the age and the number of pregnancies with the risk of hypertension. Since a significant percentage of people are unaware of the existence of hypertension, changing diet and having regular physical activity along with social support is an important strategy.
High Input Impedances Voltage-mode First-order Filters with Grounded Capacitors using CCIIs
Authors: Horng Jiun-Wei , Tsai Chun-Yang , Chen Te-Chi , Wu Chang-Ming 
Published: June 2019

Background:
Three high input impedances voltage-mode first-order filters are presented.

Methods:
The first proposed circuit uses one multi-output second-generation current conveyor, two
resistors and one grounded capacitor. The second proposed circuit uses two second-generation current
conveyors, three resistors and one grounded capacitor. The third proposed circuit uses one
multi-output second-generation current conveyor, one resistor and two grounded capacitors.

Results:
First-order lowpass and allpass filters can be simultaneously obtained in the first proposed
circuit. First-order lowpass, highpass and allpass filters can be simultaneously obtained in the second
proposed circuit. The third proposed circuit can realize first-order allpass filter.

Conclusion:
All the proposed circuits have the advantages of high input impedances and using only
grounded capacitors.
Utilização da dieta cetogênica como estratégia para o manejo de pacientes com epilepsia refratária: uma revisão da literatura
Authors: Dos Santos Douglas Kovacs , Errante Paolo Ruggero , Pontes-Junior Luis Carlos Barbosa , Raphael Junior Alexandre , Raphael Junior Alexandre , Colombo-Souza Patrícia , Ferraz Renato Ribeiro Nogueira , Menezes-Rodrigues Francisco Sandro 
Published: June 2019

Introdução: A epilepsia é uma doença que afeta milhões de pessoas em todas as partes do mundo. Crises epilépticas se apresentam nos pacientes de forma parcial ou generalizada, dependendo do grau de atividade da doença. Atualmente, há muitos fármacos disponíveis no mercado, os quais possuem diversos mecanismos de ação e que podem ser utilizados de forma isolada ou concomitante. No entanto, em alguns pacientes, principalmente, em crianças e adolescentes, esses fármacos se mostram ineficazes e incapazes de promover o controle tanto da frequência quanto da intensidade das crises epilépticas, a quais são denominadas de epilepsia refratária. Assim, a busca por tratamentos alternativos capazes de controlar as frequência e intensidade das crises epilépticas refratárias é incessante e intensa e, dentre as estratégias usadas, atualmente, destaca-se a dieta cetogênica (DC), que consiste numa elevada ingestão de lipídios e baixa ingestão de carboidratos e proteínas e que tem fornecido uma melhora na qualidade de vida de pacientes, principalmente, em crianças e adolescentes com epilepsia refratária. Objetivo: Realizar uma revisão da literatura sobre os benefícios causados pela utilização da DC, como tratamento adjuvante e/ou alternativo, no tratamento da epilepsia refratária, principalmente, em crianças e adolescentes. Metodologia: O estudo foi realizado por meio de uma revisão bibliográfica e integrativa da literatura, através da compilação de artigos científicos e livros sobre o tema proposto. As informações foram pesquisadas na base de dados Google acadêmico, Scielo e PubMed. As palavras-chave utilizadas para a busca dos artigos científicos foram: Epilepsia, Epilepsia refratária, Dieta cetogênica. Para a elaboração deste estudo foram pesquisadas publicações a partir de 2008 a 2018, levando em consideração o fator atualidade e relevância do tema, cujo título estabelecia a relação com o estudo. Das publicações encontradas, 22 foram utilizadas. Conclusão: Conclui-se que a DC se apresenta como uma importante opção terapêutica muito segura, barata e eficaz e que, por isso, pode ser utilizada no manejo de pacientes com epilepsia refratária, principalmente, em crianças e adolescentes.
Komunikasi Keluarga Dalam Menanamkan Nilai-Nilai Keislaman Pada Remaja Di Desa Tanjung Aman Lampung Utara
Authors: Sarwinda Sarwinda 
Published: June 2019

Penelitian ini membahas tentang proses komunikasi antara orang tua dengan remaja yang kurang baik dalam memberikan pemahaman tentang nilai-nilai keislaman. Adapun permasalahannya bagaimana komunikasi keluarga dalam menanamkan nilai-nilai keislaman pada remaja, dan bagaimana peran orang tua dalam menanamkan nilai-nilai keislaman pada remaja di Desa Tanjung Aman Kotabumi Lampung Utara. Penelitian ini bertujuan untuk menambah wawasan kepada keluarga bahwa penting komunikasi dalam keluarga dalam menanamkan nilai-nilai keislaman pada anak remja dan meningkatkan pemahaman remaja tentang nilai-nilai agama itu sendiri.
Metode yang digunakan dalam penelitian ini yaitu dengan interview, obsevasi, dan dokumentasi. Peneliti langsung turun ke lapangan dan melakukan interview kepada orang tua dalam menanamkan nilai-nilai keislaman pada anaknya, bahkan ada yang orang tuanya mengajak dan memberi contoh langsung pada anaknya dalam melakukan solat diawal waktu dan melaksanakan pengajian rutin. Temuan yang didapat dalam hal ini orang tua tidak serta merta hanya bertanya atau memberikan perintah saja tetapi mengajak untuk solat dan mengaji bersama-sama, komunikasi yang dibangun adalah dalam bentuk perhatian dan pengawasan, serta pengetauan agama orang tua juga berpengaruh terhadap nilai-nilai keislaman anaknya.
Temuan dalam proses komunikasi keluarga dalam menanamkan nilai-nilai keislaman pada remaja di Desa Tanjung Aman berjalan dengan baik, orang tua sebagai komunikator menyampaikan pesan berupa nilai-nilai keislaman pada anak remaja sebagai komunikan, dan dari pesan yang diterima anak itu memberikan feedback sehingga terjadilah komunikasi yang harmonis. Peran orang tua sendiri dalam menanamkan nilai keislaman pada anaknya yaitu sebagai pemberi arahan pada anak dan juga mendidik anak dengan cara yang baik sesuai dengan perintah Allah SWT.

Kata kunci : Komunikasi Keluarga Dalam Menanamkan Nilai-Nilai Keislaman
Diagnostic capabilities of monitoring of redox potential in blood plasma of lung transplant patients
Authors: Evseev A. K. , Pervakova E. I. , Goroncharovskaya I. V. , Tarabrin E. A. , Khubutiya M. Sh. , Goldin M. M. 
Published: June 2019

Introduction. Monitoring of redox potential (platinum electrode open circuit potential) in biological media (serum, blood plasma) is one of the promising methods for diagnosing and predicting the development of complications in patients in the early post-transplantation period. The study of the diagnostic capabilities of this technique in patients after lung transplantation is highly relevant.The objective was to assess the diagnostic and prognostic capabilities of monitoring platinum electrode open circuit potential in blood plasma of lung transplant patients.Material and methods. The data obtained at monitoring of platinum electrode open circuit potential in blood plasma and clinical laboratory test results of 14 patients after double lung transplantation surgery were analyzed. The platinum electrode open circuit potential value in the blood plasma was measured by the potentiometric method.Results. The study demonstrated the differences in the dynamics and values of platinum electrode open circuit potential in the blood plasma between the lung transplant patients with a favorable outcome and those with a fatal outcome. Wave-like segments on the relationship curves of the platinum electrode open circuit potential in blood plasma to time coincided with inflammatory markers (C-reactive protein, stab neutrophils, erythrocyte sedimentation rate) activation. Statistically significant correlations between platinum electrode open circuit potential values in blood plasma and clinical laboratory test results were revealed.Conclusion. The informative value and diagnostic capabilities of the technique of the platinum electrode open circuit potential measurement in blood plasma of lung transplant patients have prospects of using its results as a criterion for assessing the patient’s condition and improving the quality of therapy.
Pulmonary and intestinal tuberculosis in a kidney transplant recipient
Authors: Kantariya R. O. , Vatazin A. V. , Zul’karnayev A. B. , Stepanov V. A. 
Published: June 2019

Introduction. Tuberculosis is one of the most common infections in the general population, as well as among the recipients of solid organs. In kidney transplant recipients, the diagnosis of tuberculosis is often extremely difficult to make because of unclear clinical and radiological symptoms, and a highly frequent atypical (extrapulmonary) localization. The tuberculosis treatment in patients on drug immunosuppression is a significant problem.Clinical case. At five years after renal transplantation, the patient noted the onset of fever up to 38 degrees C. It was suspicious of respiratory infection. Chest X-ray, computed tomography, and ultrasound examination of the graft revealed no pathology. Antibacterial and antiviral therapy brought stable improvement. A repeated computer tomography demonstrated an enhanced pulmonary pattern in S6 of the left lung with visualization of small grouped lesions located peribronchially, the terminal ileitis in the abdominal cavity: (an intensive contrast accumulation in the mucosa of the affected part of the small intestine, the mesentery hypervascularity at this level). A colonoenteroscopy with a ileum intestine biopsy was performed; the findings were highly consistent with a tuberculous process. A targeted treatment of tuberculosis was carried out, which had a marked positive trend.Conclusion. Thus, the diagnosis of tuberculosis in kidney transplant recipients is complex; the clinical signs and instrumental test results are often ambiguous, which greatly complicates the timely diagnosis. An integrated approach with the use of modern diagnostic methods is required.