bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of complete blood cell and inflammatory parameters in patients with alopecia areata: Their association with disease severity
Authors: İslamoğlu Zeynep Gizem Kaya , Demirbaş Abdullah 
Published: September 2019

AbstractBackgroundAlopecia areata (AA) is a chronic inflammatory disease characterized by non‐cicatricial hair loss. The cause of the disease is still unknown. It can appear at any age and occurs in 0.2% of the general population. Red cell distribution width (RDW), mean platelet volume (MPV), plateletcrit (PCT), the ratio of neutrophils to lymphocytes (NLR), and the ratio of platelets to lymphocytes (PLR) have all been reported as inflammatory markers in recent studies. However, these parameters have not been investigated in AA patients.AimWe investigated the haematological and inflammatory parameters of AA and considered their association with disease severity.Patients/MethodsOne hundred and five patients with AA and 108 healthy controls were enrolled in the study. RDW, MPV, PCT, NLR, PLR, erythrocyte sedimentation rate (ESR), and C‐reactive protein (CRP) were studied retrospectively. Disease severity was evaluated by using the Severity of Alopecia Tool (SALT) score.ResultsThere were no statistically significant differences between RDW, MPV, PCT, NLR, and PLR levels in AA patients and in healthy controls. Only the CRP values were significantly higher in the AA group.ConclusionComplete blood count (CBC) parameters are low‐cost tests that can be used to define inflammation levels in inflammatory diseases. Our study shows that CRP can be used as a marker in diagnosing AA.
Minilifting technique for treatments of the lower third of the face and anterior cervical neck with tumescent anesthesia
Authors: Borges Juliano , Loureiro Fabiana 
Published: September 2019

AbstractBackgroundMinimally invasive surgical techniques with a low rate of complications and rapid return to daily activities are in high demand for dermatological procedures and include lasers, microfocused ultrasound, botulinum toxin, suture strings, and filling techniques with hyaluronic acid. The facelift, on the other hand, has been criticized for complications such as bruising, relatively slow recovery rates (lasting up to a month), facial nerve lesions, and flap necrosis. Earliest descriptions of the facelift technique described a procedure associated with skin traction and detachment. However, authors did not describe a method for SMAS plication, which is still somewhat controversial.AimsDescribe a surgical technique that reduce the signs of aging on the lower third of the face and neck with low rate of complications.MethodsThe minilifting technique described herein is capable of repositioning the superficial muscular aponeurotic system (SMAS) and removing excess skin from the neck and lower third of the face with minimal detachment, local tumescent anesthesia, a few complications, and a relatively fast return to daily activities (15 days).ConclusionPerformance of a deep dissection and excision of part of the SMAS with posterior sutures is believed to be an optimal approach, whereas authors believe that a superficial dissection is safer and provides similar outcomes compared to deep dissection. This procedure produces extremely natural and long‐lasting results.
The Effect of Risk Aversion and Loss Aversion on Equity‐Linked Life Insurance With Surrender Guarantees
Authors: Hilpert Christian 
Published: September 2019

AbstractWe price equity‐linked life insurance with surrender guarantees and account for risk preferences in the form of risk‐averse and loss‐averse policyholders in continuous time. Risk‐averse policyholders surrender their policy for higher equity index values. Compared to optimally surrendered policies, this behavior creates substantial policy value losses. In contrast, loss‐averse policyholders surrender once the surrender benefit realizes a gain but keep under‐performing policies. This disposition effect reduces the policy value relative to both optimally surrendered policies and policies surrendered by risk‐averse policyholders. Insurers in competitive markets need to estimate their policyholders’ risk preferences accurately.
Effect of protease derived from Pseudoalteromonas arctica supplementation on growth performance, nutrient digestibility, meat quality, noxious gas emission and blood profiles in finishing pigs
Authors: Liu Xiao , Yin Jia , Kim In Ho 
Published: September 2019

AbstractThis study was conducted to evaluate the effects of dietary supplementation of protease derived from Pseudoalteromonas arctica (PPA) in finishing pigs. A total of 160 pigs were used in this 10‐week trial. Dietary treatment groups were as follows: CON (basal diet); TRT1 (basal diet + 0.1% PPA); TRT2 (basal diet + 0.2% PPA); and TRT3 (basal diet + 0.3% PPA). During weeks 1–5, pigs fed with different levels of PPA‐supplemented diet showed linear increase (p < .05) in the apparent total tract digestibility (ATTD) of nitrogen (N) and linear decrease (p < .05) in the concentrations of serum total protein. During weeks 6–10, pigs fed with different levels of PPA‐supplemented diet showed a linear decrease in feed conversion ratio (p < .05). During the overall period, there was a linear decrease in feed conversion ratio (p < .05) associated with the inclusion of PPA. Pigs fed diets with 0.2% PPA supplementation had lower (p < .05) feed conversion ratio than those fed CON diet during weeks 6–10 and the overall period, and had higher (p < .05) ATTD of N than those fed CON diet during weeks 1–5. Pigs fed diets with PPA supplementation had lower (p < .05) concentrations of serum total protein than those fed CON diet on week 5. In conclusion, dietary supplementation with PPA diet has beneficial effects on growth performance, nutrient digestibility, backfat thickness and the concentrations of serum total protein.
Use of cyclooxygenase inhibitor and the risk of hepatocellular carcinoma in patients with chronic hepatitis B: A nested case‐control study using a nationwide population‐based data
Authors: Cho Kyoung Sun , Sohn Won , Lee Yeong Chan , Chi Sang Ah , Cho Ju‐Yeon , Kim Kyunga , Paik Yong‐Han 
Published: September 2019

AbstractThe study aimed to investigate the relationship between the use of COX inhibitors and the risk of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B (CHB) using a nationwide population‐based data. A nested case‐control study was conducted using the National Health Insurance Service–National Sample Cohort (NHIS‐NSC) from 2002 to 2013 in Korea. We compared the use of COX inhibitors between HCC cases and matched controls by categorizing 5 groups according to the cumulative defined daily dose (cDDD, <28, 28‐90, 91‐180, 181‐360, and >360) adjusting the use of antiviral agents. A total of 4980 patients with CHB were analysed as 996 HCC cases and 3984 matched controls. The number of COX inhibitor users (≥28 cDDD) was 358 patients (36%) and 1814 patients (45%) in the HCC group and control group, respectively. The use of COX inhibitors was significantly associated with a decreased risk of HCC development compared with nonusers (adjusted odds ratio [OR] 0.62, 95% confidence interval [CI] 0.52‐0.73, P < .001). There was a dose‐dependent inverse relationship between the use of COX inhibitors and the risk of HCC. The adjusted ORs were 0.75 (95% CI: 0.63‐0.90), 0.41 (95% CI: 0.31‐0.56), 0.38 (95% CI: 0.25‐0.57) and 0.49 (95% CI: 0.31‐0.79) for the 28‐90, 91‐180, 181‐360 and >360 cDDDs, respectively (P < .01). In conclusion, the use of COX inhibitors was associated with a reduced risk of HCC in CHB. COX inhibitor may have a chemopreventive role in HCC development in patients with chronic liver disease.
Data linkage to monitor hepatitis C‐associated end‐stage liver disease and hepatocellular carcinoma inpatient stays in England
Authors: Ireland Georgina , Simmons Ruth , Hickman Matthew , Harris Ross , Ramsay Mary , Sabin Caroline , Mandal Sema 
Published: September 2019

AbstractPersons with chronic hepatitis C (HCV) infection are at increased risk of end‐stage liver disease (ESLD) and hepatocellular carcinoma (HCC). The impact of hepatitis treatment scale‐up and elimination strategies on ESLD and HCC incidence is a critical measure of progress towards WHO targets. Data from national laboratory surveillance of HCV diagnoses were linked to inpatient care records in Hospital Episode Statistics (HES). For persons first diagnosed with HCV between 1998 and 2016, we describe the characteristics of those with ESLD and HCC and estimate incidence. Of persons diagnosed with HCV between 1998 and 2016 (104 674), 9.1% (9525) had an admission for ESLD and 2.5% (2610) for HCC. The majority of persons with ESLD and HCC were male (70.7% and 82.7%) and of white ethnicity (89.9% and 82.7%). Crude incidence of ESLD and HCC admission was 10.4 and 3.2 per 1000 person‐years, respectively. When compared to 2011‐2013, incidence of ESLD and HCC admissions in 2014‐2017 were lower (ESLD incidence rate ratio [IRR]: 0.81; 95% Confidence interval [CI]: 0.76‐0.86; HCC IRR: 0.90; 95% CI: 0.82‐1.00, P = .045). Data linkage showed considerable underreporting of HCV in HES coding for ESLD and HCC (16.0% and 11.3%, respectively). In conclusion, we found a decline in incidence of ESLD and HCC‐related inpatient admissions since 2011‐2013. Linked analysis is required for the continued monitoring of ESLD and HCC inpatient incidence. However, HES data quality issues around completeness of identifiers contribute to uncertainty in linkage and may limit our ability to robustly monitor progress towards WHO elimination goals.
ARCTIC HUNTERS, AMERICAN EXPLORERS, ADVENTURERS, AND ANTHROPOLOGISTS: The ex‐Museum of the American Indian Collection of Kayaks at the Canadian Canoe Museum
Authors: Brydon Sherry 
Published: September 2019

AbstractThis case study introduces a legacy collection of historic Indigenous Arctic watercraft from North America and Greenland, composed of ten kayaks and an umiak, that were originally at the Museum of the American Indian/Heye Foundation (whose collections now form the core collection of the National Museum of the American Indian) in New York City. The collection was formed in the early twentieth century, sold to the Kanawa International Museum of Canoes, Kayaks and Rowing Craft in the 1970s, and acquired by the Canadian Canoe Museum in the 1990s. The museum catalog cards that accompanied the transfer of the MAI collection contain information about provenance and location. This article examines the provenance information, archival documentation, and related primary sources to explore the background of some of the early‐twentieth‐century Arctic hunters and non‐Indigenous explorers and adventurers associated with these heritage items.
The pay premium for high‐potential women: A constructive replication and refinement
Authors: Dreher George F. , Carter Nancy M. , Dworkin Terry 
Published: September 2019

AbstractIn this constructive replication, we revisit a provocative study by Leslie, Manchester, and Dahm (2017). They found that gender and being designated a high‐potential employee interacted in accounting for pay and that this resulted in a reversal in the commonly observed gender pay gap favoring men. Our primary aim was to examine important boundary conditions associated with their work by (a) conducting a study using a sample that would better generalize across industries and to individuals who aspire to reach senior management, (b) adding critical control variables to the statistical models used in the pay equation, and (c) by introducing a different conceptualization of the high‐potential construct. Also, to better understand the consequences of their study, we considered an additional dependent variable that addressed pay satisfaction. Even after making these model additions, the gender by high‐potential interaction term was significant—ruling out four plausible third‐variable explanations for the Leslie et al. finding. Moreover, these confirming results were observed using a sample that represented individuals employed in a wide range of industries, who had the educational backgrounds, career histories, and motivational states typically required of candidates competing for senior executive roles. Furthermore, high‐potential women did not report higher levels of pay satisfaction, suggesting that high‐potential women did not perceive their pay premium to be an inequitable advantage and that there may be limited positive return associated with using a pay premium to retain high‐potential talent.
Use of the aqueous biphasic system as an alternative for concentration of Ascaris lumbricoides eggs, with non‐toxic separation of faecal residues and fats
Authors: Rosa Stefany Laryssa , dos Santos Bianca Martins , Soares Felipe Augusto , Loiola Saulo Hudson Nery , Inácio Sandra Valéria , Suzuki Celso Tetsuo Nagase , Sabadini Edvaldo , Falcão Alexandre Xavier , Bresciani Kátia Denise Saraiva , Gomes Jancarlo Ferreira 
Published: September 2019

AbstractObjectivesHuman enteroparasites are considered a serious public health problem in underdeveloped countries located in world regions with tropical, subtropical and equatorial climates. These parasites are commonly diagnosed by the Parasitological Examination of Faeces (PEF), performed by conventional techniques and/or commercial kits that result in tests with low‐to‐moderate sensitivity, due to the use of destructive chemical solvents to parasite structures, and to present excess adipose substance and digestive residues in their microscopic slides. In order to improve the efficacy of these tests/examinations, this study aimed to investigate a new alternative for the PEF, with the use of Aqueous Biphasic System (ABS).MethodsFor this, four ABSs containing poly (ethylene glycol), PEG (PEG‐4000 and PEG‐6000), dipotassium phosphate and sodium citrate at different concentrations in the biphasic systems were evaluated with faecal samples containing eggs of Ascaris lumbricoides.ResultsThe ABS consisting of PEG‐4000 and dipotassium phosphate, at concentrations of 55% w/w and 20% w/w, respectively, achieved 100% satisfactory results compared to the conventional TF‐Test technique in terms of preservation and concentration of A. lumbricoides eggs, with adequate separation of digestive residues, without using a centrifuge or chemical solvents that may cause harm to the parasites.ConclusionsThis study presents ABS as a new low‐cost technical principle for the detection of parasite eggs in PEF. The new technique is simple, fast, non‐toxic, not harmful to the parasite and does not require a centrifuge.
Characterization of reemergent anti‐B red blood cell antibodies in a patient with recurrent acute myeloid leukemia with ABO‐incompatible allogeneic peripheral blood stem cell transplantation
Authors: Tajima Katsushi , Takizawa Kazuya , Yasuda Takeshi , Tsumanuma Riko , Okuyama Shuhei , Kumagai Hiroaki , Omoto Eijiro , Okumura Wataru 
Published: September 2019

AbstractBACKGROUNDIsohemagglutinins against ABO antigens absent on both recipient and donor red blood cells (RBCs) increase or decrease after ABO‐incompatible hematopoietic stem cell transplantation (HSCT). However, few reports have described the changes in the isohemagglutinin titers and the characteristics in patients with recurrent hematologic conditions after ABO‐incompatible HSCT.CASE REPORTA 59‐year‐old female with acute erythroid leukemia received a peripheral blood stem cell transplant from her HLA‐haploidentical daughter. The patient was typed as group O with anti‐ A (4+) and B (4+) isohemagglutinins, while the donor was typed as group B. The bone marrow cells achieved complete donor cell chimerism on Day 13 after HSCT. On Day 120, the patient showed 97% B RBC type with persistent anti‐A (3+) and without anti‐B antibodies. On Day 375, her leukemia relapsed, and recipient type O RBCs and anti‐B antibodies sequentially reemerged. However, clinicolaboratory hemolysis and erythroid aplasia were not detected in the patient.RESULTSThe post‐HSCT sera agglutinated the allo B RBCs, but not the donor B RBCs, while the pre‐HSCT sera agglutinated both RBCs. The burst‐forming/colony‐forming units of erythroid formation from the donor peripheral blood stem cells were impaired by only the pre‐HSCT sera and not by the post‐HSCT sera.CONCLUSIONTo our knowledge, this is the first report investigating the characteristic changes of isohemagglutinins between the pre‐ and post‐HSCT sera in a patient with recurrent acute myeloid leukemia. The present study suggests that the plasma cells producing anti‐donor B RBCs in the patient have been selectively eliminated or induced into an anergic state by the post‐HSCT immunologic reconstruction.
An Alternative Approach to Substructuring in Vibratory Systems Containing Soft Rubber Isolators
Authors: Marques Viviane Cassol , Brennan Michael John 
Published: September 2019

Abstract
Built-up structures, such as airplanes, ships, and even refrigeration systems, which have many components, can be substructured to speed up and facilitate the process of calculating the vibratory response of the complete system. In many structures, there are rubber isolators that connect component parts, and these connections can each occur over a finite distributed area. It is often convenient and intuitive to substructure the system at the isolators. However, in previous work, it has been shown that the frequency response of the complete system does not always agree with the frequency response of the system calculated from the mobilities of the subsystems. It was thought that this was due to the distributed area connection of the isolators, and this motivated the study reported in this article. An investigation into some issues that occur when substructuring a system that contains soft distributed isolators is described. Using finite element models, it is shown that if a system is substructured, such that the interface between the substructures occurs at a soft rubber isolator, then there is a limited frequency range over which the frequency response function of the assembled system is accurate. It is further shown that it is far better to substructure the system, at stiff, discrete connections, if possible. The frequency range over which the frequency response of the assembled system should then be more accurate over a much wider frequency range.
Wavelet Features and Hidden Markov Model-Based Aerodynamic Instability Detection for Compressors
Authors: Wang Jiaqi , Chen Jin , Dong Guangming , Hua Hongxing 
Published: September 2019

AbstractA reliable technique is introduced to detect aerodynamic instability of compressors based on wavelet features and hidden Markov model (HMM). A single sensor is sufficient for stall warning if the position of the sensor is carefully selected. The method involves obtaining high-response pressure signal near the rotor tip close to the leading edge. Rotating instabilities band wavelet features are then extracted and trained for the HMM; using data under normal operating conditions, the performance index (PI) is calculated. Unsteady behaviors in prestall processes are discussed and casing wall pressure maps are implemented to explore the mechanism of tip leakage vortex (TLV), which are helpful in explaining the various PI results from different feature selections and probe locations. Experimental results show that the trend indices of PI suitably characterize the compressor aerodynamic instability in subsonic operation.
Experimentally Measured Hydroelastic Effects on Impact-Induced Loads During Flat Water Entry and Related Uncertainties
Authors: Tödter Simon , el Moctar Ould , Neugebauer Jens , Schellin Thomas E. 
Published: September 2019

Abstract
Extensive water entry experiments were performed to identify uncertainties associated with measured impact-induced loads acting on flat bottom ship structures. Of primary concern was the influence of air trapping on elastic structural deformations. The experimental measurements supplied the benchmark data suitable to validate computational fluid dynamics (CFD) predictions. Two bodies were tested. One body was fitted with stiffened, rigid bottom plating, and the other body was fitted with thin elastic plating. A large number of 30 repetitive runs recorded bottom pressures and forces acting on the flat bottom plating and monitored impact-induced elastic bottom strains. For each test case, high-speed videos of water entry sequences were evaluated. The resulting average peak values standard deviations quantified the uncertainty of these measurements.
The relationship between active learning, course innovation, and teaching Earth systems thinking: A structural equation modeling approach
Authors: Soltis Nicholas A. , McNeal Karen S. , Forbes Cory T. , Lally Diane 
Published: September 2019

AbstractEarth systems thinking (EST), or thinking of the Earth as a complex system made up of interworking subsystems, has been shown to reflect the highest level of knowing and understanding in the geosciences. Previous work has found four frameworks of EST that repeatedly appear in the geoscience education literature. This study aims to quantitatively build on this work by employing structural equation modeling to understand the current state of EST teaching as shown by the 2016 iteration of the National Geoscience Faculty Survey (United States; n = 2615). Exploratory and confirmatory factor analyses were conducted on survey items to understand and develop three models, one for EST teaching practices, one for course changes, and one for active-learning teaching practices. Analyses revealed that reported EST teaching practices relate back to the four EST frameworks proposed in the literature. The three models explored in this study were used to build a full structural model, where it was hypothesized that active-learning teaching practices would predict EST course changes and EST teaching. However, the model revealed that EST course changes mediate, or bring about, the relationship between active-learning teaching practices and EST teaching. In other words, the relationship between active-learning and EST teaching practices is not direct. This implies the need for continued efforts to provide professional development opportunities in both active-learning teaching practices and EST, as active-learning practices are not sufficient to implicitly teach EST skills. Results also revealed that the teaching approaches that emphasize modeling and complexity sciences had the weakest relationship to the broader EST teaching practices, suggesting a need for more professional development opportunities as they relate to systems modeling, quantitative reasoning, and complexity sciences in the context of the Earth sciences.