bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study
Authors: Rowsthorn Ella , Cribb Lachlan , Sinclair Benjamin , Pham William , Chong Trevor , Yiallourou Stephanie , Cavuoto Marina , Vivash Lucy , O’Brien Terence J. , Shao Xingfeng , Wang Danny J.J. , Law Meng , Pase Matthew P. , Harding Ian H. 
Published: November 2024

AbstractFluid transport in the neurovascular unit (NVU) is essential for maintaining brain health through nutrient delivery and waste clearance. NVU integrity and fluid regulation can be assessed through MRI measures, including water exchange rate through the NVU (BBB kw), enlarged perivascular spaces (ePVS), cerebral blood flow (CBF), free water (FW), and white matter hyperintensities (WMH). This study investigated relationships between these MRI measures using Bayesian mixed models, and their variation with chronological age or biological brain age (brainageR) using linear regression in 132 non-clinical older adults (mean age=67 years; 68% female). BBB kwpositively associated with CBF (β^=0.08, 95% credible interval (CI)=[0.02,0.15]). FW positively associated with both ePVS (β^=0.44, CI=[0.30,0.63]) and WMH (β^=0.13, CI=[0.04,0.21]). BBB kw, CBF and ePVS decreased with age, while FW and WMH increased (allp<.05). There were no associations with brain age (allp>.05). Relationships between FW, ePVS and WMH likely reflect interconnectivity of fluid regulation within different compartments, while the relationship between BBB kwand CBF indicates a link between NVU fluid flow and vessel function. While individual metrics of NVU integrity are associated with age, their inter-relationships appear stable, providing a baseline for future research in fluid transport and vascular health in neurodegenerative disease.Abstract FigureGraphical Abstract:Neurovascular function and the fluid transport system.The brain’s fluid transport system comprises the neurovascular unit, interstitial fluid exchange in the parenchyma and venous outflow.a.The flow of water molecules from the vessel to the perivascular space through the blood-brain barrier, and subsequently into the brain (facilitated by aquaporin-4 (AQP4) channels) in quantified by BBB kw.b.Greater cerebral blood flow rate (CBF) is associated with greater BBB kw, possibly due to vessel pulsations increasing osmotic pressure.c.Enlarged perivascular spaces (ePVS) may indicate reduced fluid flow within the NVU and are associated with (d.) increased extracellular free water (FW) in the parenchyma, suggesting a link between fluid regulation within the vasculature and the surrounding brain tissue. Greater white matter hyperintensity (WMH) volume also occurs alongside increase FW, in line with WMH reflecting more severe fluid flow stagnation occurring in concert with neuroinflammation and/or neuronal demyelination.
Refueling intellectual capital toward innovation performance of SMEs in Saudi Arabia: mediating the role of entrepreneurial opportunity recognition
Authors: AlMulhim Abdullah Fahad , Mohammed Sanaa Mostafa , Benlaria Houcine , Gheraia Zouheyr 
Published: November 2024

PurposeThe objectives of this research were to inspect the relationship of intellectual capital (IC), along with its dimensions (human, structural and internal and external relational capital) with innovation performance (IP), to explore entrepreneurial opportunity recognition (EOR) as a mediator between the IC and IP of small and medium-sized enterprises (SMEs) in Saudi Arabia.Design/methodology/approachThis research used data collected via a well-structured questionnaire. The sample size was comprised of 457 participants who were owners and/or managers of SMEs in Saudi Arabia. Further, the findings were extracted from data using partial least squares (PLS) techniques.FindingsThe results indicated that all dimensions of IC, including human capital (HC), structural capital (SC), internal relational capital (IRC) and external relational capital (ERC), had a significant relation with both IP and EOR. It was also shown that EOR positively influenced IP. Furthermore, the results showed that EOR played an important role as a mediator between IC (HC, SC, IRC and ERC) and IP.Practical implicationsThe present research offered a beneficial and novel managerial and theoretical strategy for improving a given firm’s IP with the support of IC and EOR. This finding offered a vision to the management teams of SMEs for full utilization of IC and IP. The present study also provided policymakers, administration and future studies with a path to improving the production and services of SMEs to secure market advantages.Originality/valueAccording to the author’s best knowledge, the present research represented the first attempt to expose the mediating role of the EOR relationship between IC and IP. Furthermore, the present study also developed the relationship between dynamic capabilities (DC) theory, intellectual capital-based view (ICV) theory and resource-based view (RBV) theory, with variables that reveal the theoretical foundation of the study. Finally, the results of this study were verified by the existing literature.
Empathetic concern and social entrepreneurial intention: a moderated mediation model of social entrepreneurial self-efficacy and perceived cultural support
Authors: Nguyen Thuy Thi , Nguyen Tuan-Duong , Mustafa Michael James 
Published: November 2024

Purpose
This study aims to explore whether social entrepreneurial self-efficacy (SESE) mediates the empathetic concern (EC)–social entrepreneurial intentions (SEIs) relationship. In addition, drawing on institutional theory, the authors propose that the EC–SESE–SEI relationship is contingent upon perceptions of cultural support (PCS) towards social entrepreneurship in a society.

Design/methodology/approach
Data from 232 Taiwanese business and management undergraduates were used to test the proposed relationships.

Findings
SESE was found to mediate the relationship between EC and SEI. However, cultural support towards social entrepreneurship in society had a negative moderating effect on the EC–SESE–SEI relationship, suggesting that the EC–SESE–SEI relationship was stronger under conditions of low, rather than high PCS.

Originality/value
This paper provides further insights into not only the link between EC and SEI but also the conditions under which EC is translated into SEI. It also enhances the recent limited knowledge about how context and cultural attitudes and values towards social entrepreneurship shapes SEI.
Managerial interlocking networks and firm risk spillover: evidence from China
Authors: Chen Lin , Niu Ruiyang , Yang Yajie , Zhao Longfeng , Xie Guanghua , Khan Inayat 
Published: November 2024

PurposeThis paper examines the effect of managerial interlocking networks (MINs) on firm risk spillover by using a sample of Chinese A-share listed firms.Design/methodology/approachApplying the complex network approach, we build managerial interlocking networks (MINs) and leverage degree centrality to quantify a manager’s network position. To gauge firm risk spillover, we utilize the conditional autoregressive value at risk (CAViaR) model to compute the value-at-risk. Subsequently, we employ ordinary least squares to investigate the influence of MINs on firm risk spillover.FindingsOur research uncovers a direct correlation between a firm risk spillover and the status of network positions within managerial interlocking networks; namely, the more central the position, the greater the risk spillover. This increase is believed to be due to central firms in MINs having greater connectedness and influence. This fosters a similarity in decision-making across different firms through interfirm managerial communication, thus amplifying the risk spillover. Economic policy uncertainty (EPU) and Guanxi culture furtherly intensify the effects of MINs. Additional analysis reveals that the impact of MINs on the firm risk spillover is significantly noticeable in non-state-owned enterprises, while good corporate governance diminishes the risk spillover prompted by MINs.Originality/valueOur findings offer fresh insights into the interfirm risk outcome associated with MINs and extend practical guidelines for attenuating firm risk spillover with a view toward mitigating systemic risk.
Networks for healthcare delivery: a systematic literature review
Authors: Gremyr Ida , Colldén Christian , Hjalmarsson Yommine , Schirone Marco , Hellström Andreas 
Published: November 2024

PurposeNetwork configurations have been proposed as an efficient form of organisation and a promising area of research; however, a lack of conceptual clarity can be noted. The purpose of this review is to allow for a broad appreciation of network configurations and provide guidance for future studies of the concept.Design/methodology/approachA systematic literature review was conducted based on the PRISMA method; Scopus, Web of Science, PubMed and the Cochrane Library were searched for conference proceedings and journal articles describing organisational networks to integrate resources aimed at care delivery. Around 80 articles were included in the final review and analysed thematically and by use of bibliographic coupling.FindingsThe last decades have seen an increase in the frequency of articles describing networks for healthcare delivery. The most common contexts are care for multiple and/or long-term conditions. Three clusters of articles were found, corresponding to different conceptualisations of networks in healthcare: efficiency-enhancing cooperation, efficiency-enhancing integration and involvement for cocreation.Research limitations/implicationsTo increase conceptual clarity and allow the research on network configurations in healthcare to produce meta-learnings and guidance to practice, scholars are advised to provide ample descriptions of studied networks and relate them to established network classifications.Originality/valueThe current review has only included articles including networks as a key concept, which provides a focused overview of the use of network configurations but limits the insights into similar approaches not described explicitly as networks.
Enabling crowdfunding platforms in Qatar: a regulatory framework for growth and sustainable innovation based on network analysis and Monte Carlo simulation
Authors: Syarif Muhammad Fazlurrahman , Aysan Ahmet Faruk 
Published: November 2024

Purpose
This study aims to explore the structure and dynamics of Qatar’s crowdfunding ecosystem to support economic diversification and enhance entrepreneurial activities. This research focuses on analyzing the development of the industry, its regulatory environment and the collaborative dynamics among stakeholders.

Design/methodology/approach
This study used network analysis and Monte Carlo simulations to examine the interplay between various stakeholders, including entrepreneurs, to understand their roles and interconnections. This study also simulated different economic scenarios to evaluate the potential impact of crowdfunding under various market conditions and regulatory frameworks.

Findings
The analysis reveals a moderate level of crowdfunding activity characterized by conservative fundraising outcomes. The key factors identified include the pivotal role of a supportive regulatory framework and the necessity of robust stakeholder collaboration and infrastructure to ensure the industry’s resilience and growth.

Research limitations/implications
The findings are constrained by the simulated scenarios and the current state of the crowdfunding market in Qatar, suggesting that further research could explore emerging trends as the market evolves.

Practical implications
This study provides actionable recommendations for policymakers and regulatory authorities to boost a conducive environment for crowdfunding platforms. This includes enhancing connectivity among stakeholders and building robust infrastructure to support industry growth.

Social implications
This study underlines the significant social benefits of crowdfunding, including promoting innovation, supporting economic growth and facilitating entrepreneurship. These elements are vital to Qatar’s broader economic diversification strategy.

Originality/value
This study provides original insights into the crowdfunding landscape in Qatar, particularly in terms of strategic planning and risk management, using advanced simulation techniques to predict the outcomes of different regulatory and economic scenarios.
Mechanism for developing brand equity of higher education institutes using intangible resources: a serial-multiple mediation analysis
Authors: Khanna Kritika , Singh Jagwinder , Bedi Sarbjit Singh 
Published: November 2024

PurposeThis study aims to build a comprehensive model for developing higher education institutes (HEIs) brand equity by examining the impact of HEIs intangible resources, brand management aspects, attachment strength and student’s contemporary citizenship behavior (CCB).Design/methodology/approachData were gathered through a self-administered questionnaire from Indian students and alumni (n = 703). The study examines the proposed comprehensive model through serial and multiple mediation analysis.FindingsThe study unfolded “service quality? brand image? attachment strength? word-of-mouth? brand equity” as the most significant path to develop HEI’s brand equity.Research limitations/implicationsThis study pioneers an empirically validated mechanism for developing brand equity in HEIs, addressing gaps identified by previous studies and offering a theoretical framework that elucidates how HEIs can leverage intangible resources through strategic brand management to foster attachment and influence positive student behaviors, thereby contributing to the development of HEI brand equity.Practical implicationsHEIs need to understand that relying solely on tangible aspects leads to short-lived effects. To maintain a lasting competitive advantage, HEIs should focus on crafting a rich historical narrative, retaining talented faculty and staff and earning respect from the public to build a lasting reputation.Originality/valueThis study develops the mechanism for developing brand equity of HEIs using its valuable, rare and inimitable intangible resources. Along with the introduction of novel constructs like competence, heritage and word-of-mouth to existing study, the proposed conceptual model is premised on the theory of self-congruence, social-exchange theory and CCB.
Green performance appraisal impact on organizational sustainability: exploring the role of green knowledge and behavior in Lebanese firms
Authors: Sadek Karim , Karkoulian Silva 
Published: November 2024

Purpose
This research aims to reveal the impact of Green Performance Appraisal (GPA) on Organizational Sustainability (OS) and to explore the effect of GPA on Employee Green Behavior (EGB). Moreover, it investigates the factors underlying the relationship between GPA, EGB and OS. Further, it intends to examine the role of Green Knowledge Usage (GKU) in the relationship between EGB and OS.

Design/methodology/approach
Partial Least Squares Structural Equation Modelling technique, SPSS and the Smart PLS 4 Software were used to test the hypotheses and the data collected via a cross sectional online survey conducted among Lebanese firms registered in the local chamber of commerce.

Findings
The results show that GPA plays a significant role in enhancing EGB and in promoting OS. It proves also that EGB partially mediates the relationship between GPA and OS. Further, it reveals the moderating role of GKU in reinforcing the relationship between EGB and OS.

Research limitations/implications
Although the study has some limitations related to the limited sample targeted and the cross-sectional data used, the findings provide various managerial implications and help in enhancing OS. It also advances green human resources management practices theoretically and practically.

Originality/value
This research aims to fill the gaps observed in the literature and explores the impact of GPA on OS examining the mediating role of EGB and the moderating effect of GKU.
Temporal dynamics of stream algae under the combined impacts of climate and land‐use stressors
Authors: Penk Marcin R. , Kelly Ann‐Marie , Kelly‐Quinn Mary , Piggott Jeremy J. 
Published: November 2024

Abstract

Ecosystems are increasingly challenged by the multiple facets of climate change, coupled with intensifying land‐use pressures. These co‐occurring stressors can interact in complex ways, but we lack an empirical understanding of the impact of higher‐order interactions on temporal patterns.

Using 128 flow‐through circular stream mesocosms, we investigated the individual and combined effects of two climatic stressors (CO2 enrichment, flow variability) and two land‐use‐related stressors (siltation, light—as lack of shading) on algal communities and net ecosystem productivity (NPP) in a full‐factorial design. The sediment pulses coincided with high flow to mimic erosion events, whereas CO2 and light disturbances were applied continuously, as they would in nature.

Sediment emerged as a key stressor for algal biomass. Land‐use stressors had more pervasive individual effects, whereas climate‐change‐related stressors were more important in up to three‐way interactions with other stressors. However, CO2 was a key driver of NPP, followed by sediment and light, whereas flow variability was only important in interactions with other stressors. The effects of sediment and flow on algal biomass depended strongly on their temporal patterns. The combined effect of an increasing number of stressors on algal biomass appeared to reach saturation with three active stressors, with no apparent additional effect caused by the fourth stressor.

Synthesis. Sediment emerged as a key stressor in streams. Despite the mounting evidence and the multitude of available mitigation strategies, this problem persists worldwide. The complex interactions uncovered in our study illustrate context‐dependency that can be masked in two‐factor experiments. Our findings also highlighted that temporal patterns of individual and co‐occurring stressors can determine the ecological outcome.
Influence of (ultra‐)processing methods on aquatic proteins and product quality
Authors: Chen Jingjing , Ma Huawei , Guo Ailing , Lv Min , Pan Qingyan , Ya Shiya , Wang Hui , Pan Chuanyan , Jiang Linyuan 
Published: November 2024

AbstractAquatic products are a high‐quality source of protein for humans, and the changes in protein during aquatic product processing are crucial for nutritional value, product performance, and consumer health. With the advancement of science and technology, aquatic product processing methods have become increasingly diverse. In addition to traditional methods such as thermal processing (steaming, roasting, and frying) and pickling, emerging non‐thermal processing technologies, such as high pressure, ultrasound, and irradiation, are also being applied. During (ultra‐)processing, aquatic products undergo complex biochemical reactions, among which protein oxidation significantly affects the quality of aquatic products. Protein oxidation can alter the molecular structure of proteins, thereby changing their functional properties and ultimately impacting product quality. This paper primarily explored the effects of protein changes under different processing methods on aquatic product quality and human health, as well as techniques for controlling protein oxidation. It aims to provide a theoretical basis for selecting appropriate processing methods, improving aquatic product quality, and controlling protein oxidation in aquatic products, and to offer scientific guidance for practical production.
How ultrasonication treatment drives the interplay between lysinoalanine inhibition and conformational performances: A case study on alkali‐extracted rice residue protein isolate
Authors: Liu Jiarui , Wang Yang , Shi Wangbin , Meng Xiangren , Mintah Benjamin Kumah , Dabbour Mokhtar , Zhang Zhaoli , He Ronghai , Ma Haile 
Published: November 2024

AbstractLysinoalanine (LAL) formed during alkaline extraction of rice residue protein (RRPI), which limited its application in the food industry. In this study, the influence of ultrasonication parameters (acoustic power density, ultrasound duration, and ultrasound temperature) on the inhibition of LAL formation and conformational attributes of RRPI during alkaline extraction was elucidated. The results suggested that the acoustic power density substantially modified the chemical interaction forces between RRPI molecules. At a power density of 60 W/L, the ionic bonds (14.37%) and hydrophobic interactions (49.28%) reached the maximum, while hydrogen bonds (15.29%) and disulfide bonds (21.06%) reached the minimum. Moreover, acoustic power density at 60 W/L caused a decrease of 18.02% and 12.2% in α‐helix, and β‐turn, respectively, shifting toward β‐sheet, random coil, with an increase of 7.31% and 36.16%. Following ultrasonication, the protein particle size distribution curve shifted in the direction of smaller particle size, forming a relatively concentrated and uniform protein distribution. Sonication power, temperature, and time decreased the absolute value of Zeta potential. Furthermore, significant destruction in microstructure was elicited by sonication, which made the structure looser and more microparticles. Pearson correlation analysis suggested that the inhibition in the levels of LAL was most influenced by the increase of sulfhydryl groups and Zeta potential, as well as the reduction of α‐helix content, in which the alteration of the total sulfhydryl group content had a great impact on the Zeta potential and the free sulfhydryl group. The principal component analysis demonstrated a notable correlation between the total sulfhydryl group and both the Zeta potential and free sulfhydryl group of RRPI.