bluuebunny/crossref_metadata_2025_split huggingface dataset:
Markers of Poor Prognosis in Non-ST Segment Elevation Acute Coronary Syndromes Without Revascularization: A 3-Year Survival Analysis
Authors: Parkhomenko Alexander , Dovgan Natalia , Lutay Yaroslav , Kozhukhov Sergey 
Published: August 2018

Introduction: The non-ST elevation acute coronary syndrome (NSTE-ACS) account for more than 50% of the total number of patients with ACS. The mortality rates after NSTEMI are not significantly different when compared with patients with ST-segment elevation myocardial infarction. Aim: The aim of the present study was to investigate whether the assessment of clinical, laboratory and instrumental data during hospital stay provide any additional independent information in predicting the 3-year major cardiac events after NSTE-ACS. Methods: We observed 490 consecutive patients, who were admitted to the emergency cardiology department with NSTE-ACS. The patients' baseline characteristics, blood analysis, left ventricle (LV) and renal function data were assessed and analyzed. The median follow‑up time was 36 months. The endpoint was cardiovascular death. Results: The results of our study show that the risk of cardiovascular death during the three years follow-up after multivariate adjustment increases with older age (> 64 years), history of diabetes, prior myocardial infarction and history of angina pectoris, lower ejection fraction (<50%), degree of myocardial hypertrophy (the thickness of the interventricular septum >1.25 mm) of the LV and the degree of diastolic dysfunction (E-wave deceleration time (DT) < 150 ms), silent myocardial ischemia during first 24-hours, high pulse pressure on Day 1 (>49 mm Hg), glucose level > 7.5 mmol/l on admission and moderate kidney dysfunction (CrCl <60 ml/min). Conclusion: In patients with NSTE-ACS, we report the cardiovascular death risk factors within the 3-year follow-up period in the present study. We thus conclude that it is important to identify the patients with high risk of future cardiovascular complications.
Influence of technogenic loading of pyrogenic origin on the geochemical migration of heavy metals
Authors: Buts Y. , Asotskyi V. , Kraynyuk O. , Ponomarenko R. 
Published: August 2018

The study of geochemical aspects of the transformation of migration properties of heavy metals under the influence of anthropogenic loading of pyrogenic origin has been given insufficient attention. We studied the concentration of heavy metals in soils by atomic absorption analysis. The results indicate the transformation of their migration properties. The diversity and versatility of behaviour of chemical elements in environmental components after fire was noted. In different ecological conditions, it is possible to observe a wide range of quantitative values of geochemical migration or accumulation of any particular chemical element. The analytical results show that the contents of migrant elements, pH values, areas of disasters which are approximately in the same conditions, but passed by the grass or upper fire differ quite tangibly. Heavy metals that hit the environment can form difficult soluble hydroxides. In addition, in the soil solution, there is a probability of the formation of hydroxocomplexes with different amounts of hydroxide ions by metals. The range of precipitation of hydroxides and the region of predominance of soluble hydroxocomplexes have been studied by constructing concentration-logarithmicdiagrams. On the basis of the calculations it can be argued that the influence of technogenic loading of pyrogenic origin influences the geochemical migration of heavy metals . Compounds Fe3+ at the pH = 4.5-14, Cu2+ at pH = 7-14, Cr2+ at pH = 7-9, Zn2+ at pH= 8-11, Ni2+ at pH = 8-14 have the lowest migration potential. Compounds Pb2+ at pH = 9-12, Fe2+ - pH = 9.5-14 have the lowest migration potential also. In a more acidic environment, soluble substances are formed, but at a pH increase of only 0.5-1, they can decrease their mobility by an order of magnitude which contributes to their concentration in the soils after the fire. In a neutral soil reaction, most of the heavy metals (Al, Cr, Zn, Cu, Fe (II), Ni) are in a slightly soluble form (in the form of hydroxides), with insignificant, migration capacity which leads to the accumulation of these chemical elements in the soil. It is necessary to allocate heavy metals moving in a neutral environment (Fe (II), Cd, Co, Mg, Mn) into a separate group. Any increase in pH values contributes to their fixation. The obtained calculations can be used to predict the geochemical migration of heavy metals in soils which result from anthropogenic disasters of a pyrogenic origin.
METHODOLOGY FOR STUDYING THE PROBLEM OF WAR AND PEACE IN PERSONAL RELIGIOUS BELIEFS
Authors: Z. V. Shwed  
Published: August 2018

Purpose. The main purpose of this paper is to consider the methodological peculiarities in the formation and interpretation of war and peace, in the context of the spiritual (irrational) rethinking by humanity and the nature of social phenomena, among which a special place is occupied by the political and legal phenomena of the modern world. This involves solving the following tasks: firstly, to reveal the meaning of modern approaches in understanding the features of religious fundamentalism, and, secondly, to reconstruct the dynamics of transformations in representations of war and peace, in the context of the spiritual practices of the present. Theoretical basis. The author's analysis is based on the systematic reconstruction of modern theoretical models of understanding religious fundamentalism and its connection with the subject of modern anthropological research. The resulted fact that the taxonomy of different types of religious fundamentalism includes more political, legal and economic markers does not provide an answer to the question of what the qualitative influence of the fundamentalist ideas is on the spiritual component of a person's life. Appealing to the problem of religious fundamentalism, in the context of rethinking the phenomena of war and peace, is associated with the actualization of these phenomena in the communicational, media and ideological spheres. That is why, in the context of this analysis, we take into account the main modern approaches in the provisions of religious traditions. These articulate the problems of threat to the global world in the context of actualization and return of the religious factor into the everyday life of a person, including through politics. Originality. The author proves that when analyzing the religious aspect in the reinterpretation of ideas about war and peace, it is necessary to consider, as a doctrinal component, certain types of religious belief doctrines, as well as the individual psychological peculiarities of man. These peculiarities, which are manifested in different types of beliefs, can be verified by the clues in the analysis of religious practices, which represent the meaningful components of the religious doctrine. Conclusions. The reasons for forming ideas about war and peace in theistic religions are a number of provisions related to the nature of the world and of man. They are the result of the manifestation of the act of the Supernatural Essence. In the tradition of rethinking the vocation of man in the context of fundamentalist discourse, these ideas acquire the status of spiritually determined and politically achievable goals. These are conceived in connection with the establishment of the Divine Plan, and they overcome the gap between the material world and the ideal world order.
Dramatic Response to Concurrent Anti-PD-1 Therapy and Radiation in Resistant Tumors with Sarcomatoid Differentiation
Authors: Tolay Sameer , Nair Ranjit , McIntosh Alyson F. , Sopka Dennis M. , Nair Suresh G. 
Published: August 2018

Abstract
A substantial fraction of patients demonstrate resistance to immune checkpoint inhibitors, which limits their use. Use of radiation concurrently with checkpoint inhibitors has been shown to boost immune responsiveness, resulting in significant tumor regression in patients with metastatic melanoma. However, it is unknown whether radiation could play a role in reversing the inherent resistance to checkpoint inhibition in certain tumor types. Most trials testing this concurrent approach exclude such modestly responsive tumors and pursue checkpoint inhibition using anti-cytotoxic T-lymphocyte-associated protein 4 antibody (anti-CTLA-4, ipilimumab). The efficacy of anti-programmed-death-1 (anti-PD-1) therapy when used concurrently with radiation is less known but remains an attractive option due to less autoimmune toxicity compared with CTLA-4 inhibition. In this first reported experience, we have safely and effectively combined anti-PD-1 therapy (nivolumab) concurrently with radiation to treat two patients with relapsed sarcomatoid renal carcinoma and heavily pretreated pleomorphic sarcoma. Both patients experienced a dramatic response that was durable.
Koroner Anjiografi Laboratuvarına Sevki Yapılan Hastalarda; Depresyon, Anksiyete Ve Koroner Arter Hastalığı Ciddiyeti İlişkisi
Authors: AKKAYA Süleyaman , POLAT Cegerğun , EDE Hüseyin , ÖZTÜRK Önder 
Published: August 2018

AMAÇ: Bu çalışmanın amacı, koroner anjiyografi (KAG)
laboratuvarına sevk edilen hastalarda koroner arter hastalığı (KAH) varlığının
anksiyete ve depresyon gibi psikolojik bozuklıuklar ile ilişkisini
değerlendirmektir. YÖNTEM
VE GEREÇ: Koroner anjiografi
yapılan 163 hasta ardışık olarak çalışmaya dahil edildi. Tüm hastaların
sosyodemografik özellikleri, kardiyovasküler risk faktörleri, klinik
özellikleri ve mevcut kullandığı ilaçları kaydedildi. Koroner anjiyografi
sonrası anksiyete ve depresyon seviyeleri, Hastane Anksiyete ve Depresyon
Ölçeğine (HADÖ) göre incelendi. KAH ciddiyetini sınıflamak için KAG sonuçlarına
göre hastalar aşağıdaki gibi sınıflandırıldı: perkütan koroner girişim (PKG);
koroner by-pass greftleme (CABG); non-kritik koroner lezyonlar; normal koroner
arterler. Sosyodemografik özellikler, klinik özellikler, koroner arter
ciddiyeti HAD ölçümleriyle uygun biçimde karşılaştırıldı. BULGULAR: Çalışmaya 62 kadın hasta (%38) dahil
edildi. 62 hastaya PKG uygulanıken 30 hasta CABG’ye gönderildi. 55 hastad
non-kritik KAH varken 12 hastada normal koroner arterler (yavaş akım dahil)
mevcuttu. Sosyodemografik faktörler arasında sadece kadın hastalar, düşük
gelirli hastalar veya uyku sorunu olan hastalar sırasıyla erkek hastalara,
yüksek geliri olan hastalara veya uyku sorunu olmayanlara kıyasla daha yüksek
HAD değerlerine sahipti. Sosyodemografik özellikler, kardiyovasküler risk
faktörleri, klinik özellikler ve KAG sonuçlarını içeren çok değişkenli
regresyon analizinde, anksiyete için sadece uykusuzluk varlığı (β=0,243;
p&lt;0,05) ve KAG sonuçlarının (β=0,202; p&lt;0,05) bağımsız değişken olduğu
bulunurken buna karşın depresyon için sadece yaş bulundu.

SONUÇ: Çalışmada KAH’nin hastaların anksiyete seviyeleri
ile ilişkili olabileceğini bulduk.
Effect of calming conversation on anxiety levels in Cesarean section
Authors: Kocamer Şimşek Betül , Kocamer Şahin Şengül , AKYILMAZ Ahmet Aykut , ÖZKAPLAN Şükran Esra , Özdurak İbrahim Halil 
Published: August 2018

Purpose: The purpose of this study was to determine the level of anxiety of patients undergoing elective Caesarean section under spinal anesthesia to ascertain the factors related to anxiety and the effect of calming conversation on the anxiety level.Materials and Methods: The study included a total of 156 patients as Group 1 (96) and Group 2 (60). The patients in Group 1 were distracted with calming conversationting during the surgery and in Group 2, the patient’s questions were answered but the surgical team did not calming conversation. All patients completed the the State-Trait Anxiety Inventory (STAI) questionnaire preoperatively and postoperatively. Results: The preoperative STAI scores were similar in both groups. Although midazolam administration was higher in Group 2, the postoperative STAI scores were significantly lower in Group 1. In both groups, the anxiety scores decreased significantly in the postoperative period. Smoking was found to be related with higher STAI scores. Nausea was related with higher preoperative and postoperative STAI scores. Patients who were employed related lower STAI scores. Conclusion: Calming conversationting with patients, which is easy, has no cost and does not harm the infant or mother, decreased the STAI scores better than midazolam
High ferritin in homozygous and heterozygous β-thalassemia tends to decrease oxidative stress levels
Authors: Maskoen Ani Melani , Reniarti Lelani , Sumantri Nur Imaniati , Sahiratmadja Edhyana 
Published: August 2018

BackgroundIneffective erythropoiesis and multiple blood transfusions may cause iron overload, leading to high level of ferritin in β-thalassemia patients. Iron has the ability to catalyze the production of reactive oxygen species (ROS), which can be prevented by an adequate activity of superoxide dismutase (SOD) and glutathione peroxidase (GPx). The aim of this study was to explore the association between high ferritin levels and oxidative stress among β-thalassemia patients by measuring SOD and GPx levels. MethodsThis was a cross sectional study among β-thalassemia major patients. Ferritin, SOD, and GPx were measured and compared between β-thalassemia patients with homozygous IVS1nt5 and heterozygous IVS1nt5/HbE mutations, which were the most prevalent mutations found in our previous study. The Spearman correlation test was used to analyze the data. ResultsThe ferritin levels in all β-thalassemia major patients were very high (range: 791-12,340 µg/L). However, no significant differences were observed (p=0.318) between homozygous IVS1nt5 (n=45) compared to heterozygous IVS1nt5/HbE (n=13). The oxidative stress markers SOD and GPx were not significantly different between homozygous IVS1nt5 and heterozygous IVS1nt5/HbE (p=0.450 and p=0.323, respectively). The correlations between ferritin and SOD and GPx oxidative stress levels were not significant in both homozygous IVS1nt5 and heterozygous IVS1nt5/HbE mutations. ConclusionHigh ferritin levels in β-thalassemia patients tend to decrease the GPx level in all thalassemia patients and SOD level in half of the patients, indicating that GPx and SOD may play a role in the occurrence of oxidative stress among thalassemia patients. The mechanism of oxidative stress in thalassemia needs to be further explored.
EFFECT OF RENAL DYSFUNCTION ON THE CARDIACVASCULAR SYSTEM. THE POSSIBILI TIES OF EARLY DIAGNOSIS OF THE RENAL DYSFUNCTION
Authors: Imanov B. Zh. , Murkamilov I. T. , Sabirov I. S. , Sarybaev A. Sh. 
Published: August 2018

The review is devoted to the discussion of modern concepts of the role of renal dysfunction in the development of chronic myocardial dysfunction in the context of cardio-renal syndrome (RVC) type 4. At the beginning of the review, the definition of cattle is given, general questions of pathogenesis and diagnosis of the disease are addressed. It is indicated that in patients with the initial stage of CKD, cardiovascular disorders are already registered which in the late stages of development of renal dysfunction are the leading causes of death and the true severity of the disease in patients with renal dysfunction is associated with an increased risk of cardiovascular events, rather than an achievement terminal renal failure and requiring renal replacement therapy. The progression of renal pathology leads to damage to the heart through various mechanisms and factors, both traditional and non-traditional, some of which, at the culmination of the renal continuum, are the result of the dialysis procedure itself in patients with terminal renal dysfunction. Mechanisms for the development of congestive heart failure in type 4 cattle include pressure overload (arterial hypertension) and volume (anemia, edematous syndrome), which increase in proportion to the decrease in renal function. Increase in blood pressure, changes in intracardial hemodynamics, deterioration of arterial compliance contribute to the acceleration of cardiovascular events. The role of laboratory predictors of renal dysfunction in the progression of cardiovascular disorders is discussed. The general approaches of echocardiographic visualization of the heart cavities and its importance in the diagnosis of cardiovascular diseases are discussed. Special attention is paid to the development of pulmonary arterial hypertension, changes in the left and right ventricle of the myocardium with renal dysfunction.
THE EFFECT OF PHYSICAL ACTIVITY ON SUBOPTIMAL HEALTH STATUSE
Authors: Кrylova I. A. , Slobodjanjuk A. L. , Kupaev V. I. , Nurdinа M. S. 
Published: August 2018

The patient, who has risk factors but considers himself / herself to be healthy, does not consult a doctor, but is in a suboptimal status. The study of the patient’s health at different levels of physical activity is an important issue of preventive medicine.Material and methods. 351 people (133 men and 218 women) aged 18 to 75 years after obtaining voluntary informed consent to the study were examined. Patients were divided into 8 groups according to the international physical activity questionnaire (IPAQ). In addition to the classic clinical and laboratory examination, patients were interviewed using questionnaires: suboptimal health status (SHSQ-25), hospital anxiety and depression scale (HADS), stress susceptibility questionnaire (PSS). Statistical processing was carried out by programs Microsoft Excel 2010 and Statistica 10,0.Research result. When studying the values of discovering the fact of the differences in some indicators: increase of arterial pressure in 3 and 4 group physical activity, age of women, increasing of body mass in the 2, 3, 5 and 8 groups physical activity that proves the relationship of the presence of risk factors and physical activity level of the patient. Significant differences between the actual values of the mean age and the alarm level in groups with high and low suboptimal status were revealed. Significant differences in suboptimal status were revealed, which reflected the presence of risk factors for chronic noncommunicable diseases in groups with different physical activity (age of women over 45 years old, overweight, monthly use of alcohol, the presence of hypercholesterinemia and high level of depression). Significant differences in groups with high and low indicators of suboptimal status in the presence of risk factors for chronic noncommunicable diseases are revealed: age over 45 years, increased systolic and diastolic blood pressure, high levels of anxiety. Significantly differed in the indicators of suboptimal status of the group of physical activity: 2, 3, 6 and 7.Conclusion. In groups of patients who consider themselves healthy and do not see a doctor for 3 months or more, the risk factors of chronic non-communicable diseases, more common in groups of patients who are not engaged in physical activity, were identified. Differences in indicators of suboptimal health status in the presence of risk factors of chronic noncommunicable diseases are revealed. The SHSQ-25 questionnaire objectively reflected the main screening indicators of chronic disease risk factors, it is simple to use in primary health care, it is an economical and effective tool for screening subclinical, reversible stages of chronic diseases.
The Difference of Capital Input and Productivity in Service Industries: Based on Four Stages Bootstrap-DEA Model
Authors: Xi Wei , Cheng Xiran 
Published: August 2018

Abstract
Based on the concept of productive capital stock, this paper estimated capital input by three asset types of China’s 36 service industries in 2003–2015, and compared with the results of wealth capital stock. This study found that the wealth capital stock method underestimates the actual capital input in each sector in varying degrees, and it may interference the accuracy of productivity evaluation in sectors. According to the new estimation results of capital input, this paper further applied four stages bootstrap-DEA method to estimate industrial productivity, and calculated its confidence intervals. This study found that, the years of education and the average wage have a significant positive impact on the productivity of service industries; the productive services have a short board effect in the whole service industry.
Developing Students’ Reading Culture for Academic Reading Level through Metacognitive Strategies
Authors: Pranowo Pranowo 
Published: August 2018

The development of reading culture for this academic level used the metacognitive strategies. This research was a case study in wihich the data sources were randomly drawn from various print sources by cutting off the core of the text to be analyzed. The technique of data analysis was done with two steps. The first step was to identify each data based on the categories that contained in the cognitive domain. The second step was the results of the analysis of the cognitive domains viewed based on the metacognitive strategies that included the process of planning, monitoring, and evaluate. The results of the research are that reading culture at the academic level can be developed through metacognition strategy. The steps that can be done are the reader performs cognitive process starting from remembering, understanding, applying, analyzing, evaluating, and creating. Then, every cognitive process is reviewed that the Academic reading culture can be developed with metacognitive strategies that are the type of intensive reading includes, reading comprehension, reading critically, reading creatively, reading interpretative, and reading reflective.
Influence Analysis of DPS, EPS, and PBV toward Stock Price and Return
Authors: Laurens Sebastianus 
Published: August 2018

The research revealed whether there was a significant influence of DPS, EPS, and PBV towards stock price and return. This research used a quantitative method to determine the influence of the independent variable towards the dependent variable. The quantitative analysis was conducted with statistic technic calledmultiple linear regression with data taken from Indonesia Capital Market Directory year 2005 and 2008. The result shows similar results with the previous research that there is no influence between DPS and stock price as well as there is an influence on stock return. EPS shows that there is influence of stock price and return. For PBV, there is an influence on stock price, but there is no an influence on stock return.
Selective adsorption of organic dyes by porous hydrophilic silica aerogels from aqueous system
Authors: Wei Wei , Hu Huihui , Ji Xuelin , Yan Zaoxue , Sun Wei , Xie Jimin 
Published: August 2018

Abstract
Hydrophilic silica aerogel (HSA) was obtained by sol-gel method and dried at ambient conditions and further studied for the removal of organic dyes in water. Silica aerogel was characterized by its morphology, porous structure, specific surface area and particle size distribution by scanning electron microscopy, Brunauer–Emmett–Teller and pore size distribution. The HSA after calcination had a specific surface area of 888.73 m2/g and an average particle size of 2.6341 nm. Moreover, adsorption properties of the HSA toward organic dyes – adsorption conditions, kinetics data, and equilibrium model – were investigated. The removal rate of cationic dyes (rhodamine B (RhB), methylene blue (MB) and crystal violet (CV)) by HSA was up to 90%, while the removal rate of anionic dye (acid orange 7) was not more than 30%. The maximum adsorptions were: RhB 191.217 mg/g, MB 51.1601 mg/g and CV 24.85915 mg/g, respectively. Based on the adsorption mechanism of HSA for cationic/anionic dyes, the conclusion confirmed the prospect of HSA as effective adsorbent to treat cationic dyes wastewater.