bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASI sebagai faktor protektif terhadap autisme
Authors: Bawono Kornelius Dandung , Herini Elisabeth Siti , Wandita Setya 
Published: March 2019

Background: The prevalence of autism has risen in the last decades. Risk factors of autism remain controversial and were thought to be multifactorial. One hypothesis stated that it may be caused by leaky gut theory and long chain polyunsaturated fatty acid defi ciency. Optimal duration of breastfeeding has been proven to reduce risk of gastrointestinal infection and improve child’s cognitive ability.Objective: To study the protective effect of optimal duration of breastfeeding to reduce the risk of autism. Method: A matching case-control study was conducted in Yogyakarta and Magelang during 2008. Inclusion criteria of case group were all children with autism (diagnosed based on DSM-IV TR criteria), aged 3-10 years. Autistic children with distinct genetic disorder were excluded. Control group was matched on gender, age, and their residence. Breastfeeding pattern and other related information were obtained by direct interview. McNemar test, conditional multivariate logistic regression, and Maentel-Haenszel test were used to fi nd factors that are signifi cantly associated with autism.Result: There were 52 children with autism and 104 control subjects. The mean age was 5 years old. The analysis revealed that breastfeeding duration for less than 6 months was a signifi cant risk factor for autism (ORMH=2,05; RK 95%:1,03-5,01), as well as history of abnormal birth weight (OR=3,36; RK 95%:1,37-8,44). There was dose-effect gradient as breastfeeding duration affected risk of autism. There was no differences on the duration of exclusive breastfeeding between the two groups. Conclusion: Breastfeeding duration of less than 6 months was a signifi cant risk factor for autism.
Efek hipoglikemik tepung komposit (ubi jalar ungu, jagung kuning, dan kacang tunggak) pada tikus diabetes induksi streptozotocin
Authors: Djunaidi Carolina Sisca , Affandi Dian Rachmawanti , Praseptiangga Danar 
Published: March 2019

Background: The composite flour (50% sweet potato, 30% corn, and 20% cowpea) had proven that it could substitute 100% wheat flour for biscuit making. Intake of antioxidants, dietary fiber, and protein, had been known to reduce plasma glucose level. Objective: To evaluate the effect of composite flour diet on plasma glucose levels, body weight and food consumption of streptozotocin (STZ)-diabetic rats.Method: Thirty male Sprague-Dawley rats aged ± 2 months (± 200 grams), were divided into three groups of ten rats. They were (1) non-diabetic standard diet (ND-STD), (2) diabetic (65 mg/kg of body weight by STZ induction) standard diet (D-STD), and (3) diabetic composite flour diet (1,5 g/100 g of body weight/day) (D-CFD), for 4 weeks, 3 days after STZ induction. The plasma glucose obtained from GOD-PAP method were determined before induction, after induction and every week during diet intervention.Results: Plasma glucose levels was significantly lower in D-CFD when compared with D-STD (p<0,05). The weight of D-STD was found to be significantly decreased as compared to ND-STD (p<0,05). There were no changes in food consumption of ND-STD, D-STD and D-CFD (p<0,05).Conclusion: The composite flour could reduce plasma glucose level in diabetic rats and did not give negative effects on body weight and food consumption.
Thermogenic effect and substrate oxidation of protein from animal and plant sources in adults
Authors: Tsani Ahmed Fahmy Arif , Joo Lee Myung , Kyung Kim Eun 
Published: March 2019

Background: Changing nutrient source is one of the efforts to increase thermogenic effect (TEF) which may be significant for body weight reduction.Objective: The aim of this study was to investigate the effects of high protein diets using animal (chicken) and plant (tofu) sources on the thermogenic effect (TEF) and substrate oxidation.Method: Ten female adults (mean age 20.8+1.2 y) participated in two isocaloric diet ingestions. Each meal provided 30% of the daily basal energy need (32/26/42% as protein/fat/carbohydrates, respectively). Postprandial energy expenditure was measured by indirect calorimetry.Results: There were no significant differences in TEF and substrate oxidation. The postprandial fat oxidation rate was higher than that at the preprandial state, while carbohydrate and protein oxidation rates were lower.Conclusion: No differences were observed in TEF and substrate oxidation in animal- and plant-based diets. A high protein diet could be beneficial for weight loss, but animal protein does not appear to offer superior benefits compared to plant protein.
HIV INFECTION AMONG PREGNANT WOMEN IN THE REPUBLIC OF BASHKORTOSTAN
Authors: Latypov A. B. , Valishin D. A. , Yаpparov R. G. 
Published: March 2019

The aim of this study was to characterize the situation of HIV infection among pregnant women in the Republic of Bashkortostan in 2013-2017 on the basis of a comprehensive retrospective analysis of indicators.A comprehensive retrospective analysis of statistical data on 2734 cases of pregnancies of HIV-infected women who were on dispensary observation at the Republican center for prevention and control of AIDS and infectious diseases in the period from 2013 to 2017 was carried out. The prevalence of HIV infection in pregnant women during the study period tended to increase annually from 656.4 to 857.8 per 100 thousand pregnancies. The prevalence of HIV infection among pregnant women who have completed pregnancy by childbirth increased from 650.7 to 795.0 per 100 thousand women who gave birth. The incidence of HIV infection among pregnant women, reflecting the first identified cases, increased from 248.4 to 267.1 per 100 thousand pregnancies. The proportion of newly diagnosed HIV infections among pregnant women in the structure of the overall HIV incidence has decreased from 7.92% to 6.03%. The main route of HIV infection of pregnant women was sexual, the average for the period of its specific weight was 92.6±4.0%, the parenteral pathway accounted for 7.4±4.0%. There is a steady change in the age structure of HIV-infected pregnant women with first time established diagnosis, towards the age group of 21-30 years. If in 2013, the structure was dominated by pregnant women aged 31-40 years (60.2%), in 2017 the first place was the age group of 21-30 years (47.9%). On average, 24.7±2.3% of HIV-infected women were admitted to the study period under observation up to 12 weeks of pregnancy. The rate of vertical transmission of HIV infection averaged 2.9±1.0% over the period. Determination of the main trends of HIV infection among pregnant women, allows to assess the effectiveness of the implemented therapeutic and preventive measures, to develop and implement new methods of organization of medical care of this category of population, aimed at reducing the spread of the disease.
Intransitive Permutation Groups with Bounded Movement Having Maximum Degree
Authors: Razzagh Behnam 
Published: March 2019

Let G be a permutation group on a set withno fixed points in and let m be a positive integer. If for each subset T of the size |Tg\T| is bounded, for gEG, we define the movement of g as the max|Tg\T| over all subsets T of . In this paper we classified all of permutation groups on set of size 3m + 1 with 2 orbits such that has movement m . 2000 AMS classification subjects: 20B25
Quantitative analysis and resolution of pharmaceuticals in the environment using multivariate curve resolution-alternating least squares (MCR-ALS)
Authors: Mostafa Ahmed , Shaaban Heba 
Published: April 2019

Abstract
The study presents the application of multivariate curve resolution alternating least squares (MCR-ALS) with a correlation constraint for simultaneous resolution and quantification of ketoprofen, naproxen, paracetamol and caffeine as target analytes and triclosan as an interfering component in different water samples using UV-Vis spectrophotometric data. A multivariate regression model using the partial least squares regression (PLSR) algorithm was developed and calculated. The MCR-ALS results were compared with the PLSR obtained results. Both models were validated on external sample sets and were applied to the analysis of real water samples. Both models showed comparable and satisfactory results with the relative error of prediction of real water samples in the range of 1.70–9.75 % and 1.64–9.43 % for MCR-ALS and PLSR, resp. The obtained results show the potential of MCR-ALS with correlation constraint to be applied for the determination of different pharmaceuticals in complex environmental matrices.
Chemistry and pharmacological diversity of quinoxaline motifs as anticancer agents
Authors: Ajani Olayinka O. , Nlebemuo Martins T. , Adekoya Joseph A. , Ogunniran Kehinde O. , Siyanbola Tolutope O. , Ajanaku Christiana O. 
Published: April 2019

Abstract
Surpassing heart diseases, cancer is taking the lead as the deadliest disease because of its fast rate of spreading in all parts of the world. Tireless commitment to searching for novel therapeutic medicines is a worthwhile adventure in synthetic chemistry because of the drug resistance predicament and regular outbreak of new diseases due to abnormal cell growth and proliferation. Medicinal chemistry researchers and pharmacists have unveiled quinoxaline templates as precursors of importance and valuable intermediates in drug discovery because they have been established to possess diverse pharmacological potentials. Hence, this review highlights the current versatile routes to accessing functionalized quinoxaline motifs and harnessing their documented therapeutic potentials for anticancer drug development.
Epigenetic signature of chronic maternal stress load during pregnancy might be a potential biomarker for spontaneous preterm birth
Authors: Rogac M , Peterlin B 
Published: April 2019

Abstract
Preterm birth is the leading cause of mortality in newborn infants and can lead to significant neonatal morbidities. Spontaneous preterm birth accounts for at least 50.0% of all preterm births. We argue that chronic maternal stress load, which is an important risk factor for spontaneous preterm birth, could be represented by epigenetic signature of several specific genetic loci in the mother’s blood. A literature search was done in PubMed with the following keywords: “DNA methylation,” “epigenetics,” “maternal stress” and “preterm birth” from year 2000 to 2017. We suggest that these genetic loci might be related to vulnerability and hypersensibility of stress response during pregnancy in women with preterm births. The mother’s epi-genetic stress bioprofile was supposed to be a result of chronic maternal stress load since her birth. This epigenetic bioprofile might also be a potential biomarker for spontaneous preterm birth. DNA methylation changes are tissue-specific and human stress response manifests mostly through the central nervous system (CNS). Nevertheless, we found evidence that methylation changes of DNA isolated from blood leucocytes might be a reliable measure of stress-related epigenetic changes that occur in the CNS. Evaluating biological mechanisms through the development of simple assays based on epigenetic changes to measure chronic stress loads in expectant mothers can lead to our ability to prepare more effective measures for the prevention of preterm births, as well as leading to more effective treatment strategies for both expectant mothers and their newborns.
The Relations Between Safety Culture and Quality Culture
Authors: Wolniak Radosandław , Olkiewicz Marcin 
Published: March 2019

Abstract
The publication focuses on issues related to the culture of safety and the culture of quality. The aim of the publication is to analyze the literature on the subject of these two concepts and to present the relationship between the culture of quality and culture of safety. The integrated system should include the culture of an integrated management system, which will include issues related to individual partial cultures, for example the cultures of quality and safety presented in this publication. This concept includes all elements of the culture of quality and culture of occupational safety. This opens up new, interesting research fields, consistent with contemporary trends in both theory and practice of management sciences. Considering the practical dimension of management sciences, it is difficult to consider separately the “culture” of individual subsystems, where in most enterprises, especially industrial ones, these systems do not appear separately and are implemented in the form of an integrated system.
Operational Control in the Process Safety Assurance
Authors: Karkoszka Tatiana 
Published: March 2019

Abstract
The need of ensure the safety in the realised industrial processes results directly from their negative influence both on environment and workers’ health, and, as a result – the associated material losses. Safety management must be based on the risk management, results of which are the basis of risk acceptability assessment and taking action of the systemic character directed on risk minimisation. Those actions should guarantee technical condition of the used technological installations and monitoring and control equipment as well as organisational solutions, which in the effective manner are going to minimise the probability of occurrence of environmental and occupational accidents, and – in the case of their occurrence – minimise the influences. Therefore research on the practical solutions of process safety assurance, both in the regular conditions of work and in the time of the emergency are of the crucial meaning. That is why the value of the paper is being constituted by the authorial model of operational control, which aim is to guarantee the process safety from the perspective of the both: technical and occupational safety. The worked out model is the systemic tool giving the guidelines of operational management and allowing for the homogeneous management in the range of environmental safety and occupational safety and on the basis of – being the fundamental element of the model – risk management. The worked out model can be implemented in case of any organisation which wants to assure the safety of the realised processes by risk and system management.
The Role and Importance of Improvement Activities in Functioning of the Company in the Area of Safe and Healthy
Authors: Daroń Marta , Górska Monika 
Published: March 2019

Abstract
In the article there were presented issues related to the improvement of the occupational health and safety (OHS) management system in a selected energy industry company. The research entity belongs to the leading producers of electricity and heat in Poland. In the paper there were analyzed data on accidents in the research period covering the years 2012-2017. There was also made a short description of the company's activities regarding internal health and safety inspections carried out periodically. Furthermore, there were analyzed the activities improving the occupational health and safety management system in a selected research entity. In the paper there were also presented the sizes and types of activities (projects), that were aimed at improving the health and safety area and included in the company's business strategy. On the basis of the data and the analyzes carried out, it was possible to make a comprehensive assessment of the health and safety management system of the company and to indicate that corrective actions are continuous.
The Work Environment Management in the Aspect of the Safety Shaping at the Administration and Office Workplace
Authors: Niciejewska Marta , Kač Sonja Mlakar 
Published: March 2019

Abstract
The management of the work environment aims at shaping all elements of the work environment, also in the aspect of safety. All activities in the field of planning, organizing, conducting and controlling individual elements of the work environment are aimed at optimizing the working conditions. In office and administrative work many factors affect the level of occupational health and safety.In the paper, the selected physical factors of the work environment - lighting, noise and microclimate - at the office and administration position in order to shape a safe, ergonomic and optimal workplace have been analyzed. The article uses measurement methods using devices - noise, lighting and microclimate meters
Safety at the Workplace – Selected Issues of Personal Data Safety
Authors: Chmielarz Grzegorz 
Published: March 2019

Abstract
The paper presents the problem domain related to data safety management in the face of the threats that organisations of all types encounter in this scope. The Author’s particular concern are personal data management issues, which are of key importance for contemporary enterprises as they frequently determine wining the market advantage and growth in their competitiveness. Yet, incidents of personal data breaches, aimed at economic organisations have been on the increase in the recent years, leading not only to substantial financial losses, but what is worse, frequently resulting in damage to their reputation. Therefore, a vital issue for all enterprises is to make their employees acquainted with threats to data security and their potential harmful effects on the operations and financial results of organisations. The paper presents an analysis of breaches to personal data in organisations in a global dimension as well as analyses of their negative effects to their image and trust of their customers.
Institutional Aspects of Health and Safety at Work in Poland
Authors: Kozień Ewa , Kozień Adam 
Published: March 2019

Abstract
Health and safety at work have their legal basis in international and Polish law – source of law currently valid in Poland. For efficiently functioning system of health and safety at work it is necessary to build appropriate institutional environment. The purpose of the article is to analyse the institutional system of health and safety at work in Poland based on source of law currently valid in Poland and forming remarks de lege lata and de lege ferenda in this scope.
Safety of Formworks in the Engineering and General Construction Sector
Authors: Brózda Kinga , Selejdak Jacek 
Published: March 2019

Abstract
Formwork systems are necessarily used in the implementation of the RC (reinforced concrete) structures. Formworks are required regardless of whether a construction is monolithic or prefabricated and used to form the engineering and general structures or structural elements, such as abutments, supports and decks of the bridges, tanks and retaining walls, but also industrial and accommodation facilities etc. Ensuring the OHS (occupational health and safety) during transport, assembly and disassembly of formworks is a necessary condition for the execution of RC works in a safe and economical way. The paper presents the analysis of the safety requirements for formworks. Furthermore, the general requirements for the execution of the formwork structures were discussed. The most common organizational and technological mistakes and cased of neglects related to the operation of the formwork which lead to infringement of the OHS regulations were also identified.
Economic Aspects of Reducing Low-Stack Emission in Poland
Authors: Turek Marian , Michalak Aneta , Jonek-Kowalska Izabela 
Published: March 2019

Abstract
The objective of the paper is to present the problem of low-stack emission in the economic and financial context. The paper presents the results of preliminary research based on literature review and environmental reports. After completing the selection of publications and data extraction, which could help to describe the issue raised, their analysis, comparison and generalization was conducted. The aspects presented may constitute a starting point in building a model of pricing the economic results of low-stack emission. In the first place the phenomenon of smog was subject to analysis, as one of the most significant consequences of low-stack emission, influencing health of human beings, environment and tangible assets. Then an attempt was made to express the previously identified results of low-stack emission in the economic and financial categories, taking into consideration the costs incurred for the purposes of completing the undertakings aimed at decreasing low-stack emission, costs avoided due to the decrease of the number of illnesses caused by low-stack emission, costs avoided due to the restriction of the negative influence of low-stack emission on the environment and on tangible assets as well as economic benefits achieved thanks to the reduction of low-stack emission.
Sustainability Indicators and Environmental Safety Management as Illustrated with an Example of the Polish Energy Sector
Authors: Skrodzka Wioletta , Kiriliuk Olga 
Published: March 2019

Abstract
Power engineering is one of the key areas of sustainable development. Many countries create new concepts of environmental safety management and modify their energy systems to be in line with the goals of sustainable development in the EU. Sustainable development indicators can be a tool for monitoring the set goals of environmental safety management. The aim of the article is to assess the environmental safety management of the energy sector in Poland in relation to EU as well as presenting the concept of sustainable energy development and indicators used to assess the development of energy in the following dimensions: social, economic and ecological. The indicators used to assess the sustainable development of energy in the following dimensions were compared: sustainable consumption and production, marking the production and consumption of energy; organizations and sites with eco-management and audit scheme (EMAS); registration climate change, marking GHG emissions and the share of renewable energy in gross final energy consumption; sustainable transport, marking the energy consumption of transport relative to GDP. The article will test the hypothesis that the structure of obtaining energy in Poland and the tempo of change in this respect differ from the EU average.
Environmental Safety as a Challenge for Management Practice in the Brewing Industry in the Era of Craft Beer Revolution
Authors: Tomski Piotr , Dunay Anna 
Published: March 2019

Abstract
The objective of the present paper is the analysis of the selected problems of environmental safety associated with the operation of craft breweries in the conditions of craft beer revolution. The study is the author’s considerations on the selected issues associated with the impact on the natural environment and its protection, based on the review of the literature and the analysis of experiences of the existing craft breweries.
Basis of Biomass Grinders Sustainable Designing
Authors: Kruszelnicka Weronika , Tomporowski Andrzej , Flizikowski Józef , Kasner Robert , Cyganiuk Joanna 
Published: March 2019

Abstract
Grinding operations are one of the most commonly used preparation processes in many branches, for example in food, energy and chemical sectors. This paper focuses on the issues connected with design of technical objects in accordance with sustainable development assumptions. The aim of this study is to create methodology of sustainable design of grinding machine, including external influences involved in their operation, to increase safety, energy, economic and eco- efficiency. The problem formulated as a question: what techniques, equipment, methods, and ways should be used in design to obtain a new, better grinder structure? To resolve the problem, original methodology of sustainable design has been created.