bluuebunny/crossref_metadata_2025_split huggingface dataset:
Shipping Routes and Spice Trade in Southeast Sulawesi in the 17th and 18th Century
Authors: Zuhdi Susanto 
Published: November 2018

This paper discusses the dynamics of sea voyage and trade formed in the network of Southeast Sulawesi waters in the 17th and 18th century. Buton was chosen as a port that played the role in that network. Southeast Sulawesi as the concept of region will be positioned in the eastern and southern part of Sulawesi network, and other parts of the Nation. In addition to the strategic location connecting Makassar to North Maluku and Central Maluku, also spices as the commodities transported through this line, Buton has its own trade commodities, such as slaves, and iron tools (knives, machetes). Although it is not in large in numbers, cloves from Buton were also the target of VOC. As a collecting center port, Buton plays a role in the network of "feeder point" ports such as Raha and Tukangbesi Islands (now Wakatobi), with the entrepot, Makassar. The changes after Makassar fell into VOC’s hands has made Buton contributing more as a supplier. Although Buton was an ally of VOC, marked by a contract signed in 1613, but in some respects there was resistance, both openly as Buton War in 1755 and rebel against the ban on growing cloves (extirpation) and illegal trade (sluijkhandel). Literature review and tracking down of primary sources in the form of archives and oral tradition are important steps for further study.
Personalplanung in Großstadtbibliotheken in Nordrhein-Westfalen
Authors: Büchel Claudia 
Published: November 2018

Zusammenfassung
Der demografische Wandel hat auch die Öffentlichen Bibliotheken erreicht. Zum aktuellen Zeitpunkt zeichnet sich ab, dass zur Bewältigung der zukünftigen Ausrichtung der Bibliotheken die ausschließliche Besetzung mit bibliotheksspezifischen Fachpersonal nicht sinnvoll ist. Der Fachkräftemangel verschärft die Situation, bietet aber auch Chancen, die Einsatzbereiche in Bibliotheken für andere Professionen zu öffnen. Mit Hilfe einer Online-Umfrage wurde im Rahmen eines Praxisprojektes ermittelt, wie sich der demografische Wandel in den Großstadtbibliotheken in Nordrhein-Westfalen darstellt und welche Konsequenzen sich daraus für die Einrichtungen ergeben.
Erfahrungen aus der Ausbildungspraxis der Badischen Landesbibliothek
Authors: Fischer Michael 
Published: November 2018

Zusammenfassung
Ausgehend von der aktuellen Situation der bibliothekarischen Ausbildung in den verschiedenen Qualifikationsniveaus skizziert der Beitrag die im letzten Jahr an der Badischen Landesbibliothek erfolgten Änderungen der Ausbildungsinhalte und -organisation.
Electro-spun PLA-PEG-yarns for tissue engineering applications
Authors: Kruse Magnus , Greuel Marc , Kreimendahl Franziska , Schneiders Thomas , Bauer Benedict , Gries Thomas , Jockenhoevel Stefan 
Published: November 2018

AbstractElectro-spinning is widely used in tissue-engineered applications mostly in form of non-woven structures. The development of e-spun yarn opens the door for textile fabrics which combine the micro to nanoscale dimension of electro-spun filaments with three-dimensional (3D) drapable textile fabrics. Therefore, the aim of the study was the implementation of a process for electro-spun yarns. Polylactic acid (PLA) and polyethylene glycol (PEG) were spun from chloroform solutions with varying PLA/PEG ratios (100:0, 90:10, 75:25 and 50:50). The yarn samples produced were analyzed regarding their morphology, tensile strength, water uptake and cytocompatibility. It was found that the yarn diameter decreased when the funnel collector rotation was increasd, however, the fiber diameter was not influenced. The tensile strength was also found to be dependent on the PEG content. While samples composed of 100% PLA showed a tensile strength of 2.5±0.7 cN/tex, the tensile strength increased with a decreasing PLA content (PLA 75%/PEG 25%) to 6.2±0.5 cN/tex. The variation of the PEG content also influenced the viscosity of the spinning solutions. The investigation of the cytocompatibility with endothelial cells was conducted for PLA/PEG 90:10 and 75:25 and indicated that the samples are cytocompatible.
Normative Reference Values for High School–Aged American Football Players: Proagility Drill and 40-Yard Dash Split Times
Authors: McKay Brianna D. , Miramonti Amelia A. , Gillen Zachary M. , Leutzinger Todd J. , Mendez Alegra I. , Jenkins Nathaniel D.M. , Cramer Joel T. 
Published: November 2018

Abstract
McKay, BD, Miramonti, AA, Gillen, ZM, Leutzinger, TJ, Mendez, AI, Jenkins, NDM, and Cramer, JT. Normative reference values for high school–aged American football players: Proagility drill and 40-yard dash split times. J Strength Cond Res 34(4): 1184–1187, 2020—The purpose of this short report was to provide test- and position-specific normative reference values for the 10- and 20-yd split times (10YD and 20YD) during the 40-yd dash (40YD) as well as 10-yd split times during the proagility drill (PA) based on a large, nationally representative sample of high school–aged American football players in their freshman, sophomore, and junior classes. Cross-sectional performance data were obtained from 12 different high school American football recruiting combines between March 7, 2015, and January 9, 2016, across the United States. The sample included (n = 7,478) high school–aged American football athletes in their freshman (n = 1,185), sophomore (n = 2,514), and junior (n = 3,779) classes. Each player self-classified their American football positions as defensive back, defensive end, defensive linemen, linebacker, offensive linemen (OL), quarterback (QB), running back, tight end, or wide receiver. The results of the freshman, sophomore, and junior class were aggregated to generate test- and position-specific normative values. Mean differences were found among classes for all positions and all measurements (p ≤ 0.05) except for OL and QB PA split time (p > 0.05). Greater percent differences for all 3 variables were observed between freshman and sophomore years than between sophomore and junior years. These normative reference values will be useful for athletes, parents, coaches, and high school strength and conditioning professionals to set realistic goals for young American football athletes.
CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans
Authors: Au Vinci , Li-Leger Erica , Raymant Greta , Flibotte Stephane , Chen George , Martin Kiana , Fernando Lisa , Doell Claudia , Rosell Federico I , Wang Su , Edgley Mark L , Rougvie Ann E , Hutter Harald , Moerman Donald G 
Published: November 2018

Abstract
The Caenorhabditis elegans Gene Knockout Consortium is tasked with obtaining null mutations in each of the more than 20,000 open reading frames (ORFs) of this organism. To date, approximately 15,000 ORFs have associated putative null alleles. As there has been substantial success in using CRISPR/Cas9 in C. elegans, this appears to be the most promising technique to complete the task. To enhance the efficiency of using CRISPR/Cas9 to generate gene deletions in C. elegans we provide a web-based interface to access our database of guide RNAs (http://genome.sfu.ca/crispr). When coupled with previously developed selection vectors, optimization for homology arm length, and the use of purified Cas9 protein, we demonstrate a robust and effective protocol for generating deletions for this large-scale project. Debate and speculation in the larger scientific community concerning off-target effects due to non-specific Cas9 cutting has prompted us to investigate through whole genome sequencing the occurrence of single nucleotide variants and indels accompanying targeted deletions. We did not detect any off-site variants above the natural spontaneous mutation rate and therefore conclude that this modified protocol does not generate off-target events to any significant degree in C. elegans. We did, however, observe a number of non-specific alterations at the target site itself following the Cas9-induced double-strand break and offer a protocol for best practice quality control for such events.
A cohort study of patients seeking Internet gaming disorder treatment
Authors: Han Doug Hyun , Yoo Minkyoung , Renshaw Perry F. , Petry Nancy M. 
Published: November 2018

Background and aims
Although Internet gaming disorder (IGD) is included as a condition in the fifth edition of Diagnostic and Statistical Manual of Mental Disorders, little is known about its nature or treatment response. This study is a follow-up of 755 patients who received professional treatment for IGD over a 5-year period.

Methods
The initial recommended treatment course lasted for 8 weeks, with additional care provided as needed. Treatment completion rates in the complete sample, as well as baseline predictors of treatment completion and long-term recovery among the 367 patients who completed the follow-up, are reported.

Results
Nearly two thirds of patients who initiated treatment for IGD completed the 8-week psychotherapy. Of these, about two thirds who had not recovered completely by the end were offered additional care. Independent predictors of extended treatment were higher baseline scores on the Young Internet Addiction Scale, Beck Depression Inventory (BDI), and Korean-Attention Deficit Hyperactivity Disorder-Rating Scale (K-ADHD-RS). Between 1 and 5 years later, 33.5% of the complete sample was considered as recovered from IGD. Significant predictors of recovery from IGD were older age, earlier admission to the clinic, lower baseline scores on the BDI and K-ADHD-RS, and no offer of extended treatment.

Discussion and conclusions
The majority of the patients seeking treatment for IGD continued experiencing difficulties and randomized controlled trials of interventions, which are needed to be conducted to improve outcomes. Age, family, social factors, and psychological symptoms should be considered, while designing and evaluating interventions, because they impact initial and sustained response to treatment for IGD.
Short version of the Smartphone Addiction Scale in Chinese adults: Psychometric properties, sociodemographic, and health behavioral correlates
Authors: Luk Tzu Tsun , Wang Man Ping , Shen Chen , Wan Alice , Chau Pui Hing , Oliffe John , Viswanath Kasisomayajula , Chan Sophia Siu-chee , Lam Tai Hing 
Published: November 2018

Background and aims
Problematic smartphone use (PSU) is an emerging but understudied public health issue. Little is known about the epidemiology of PSU at the population level. We evaluated the psychometric properties of the Smartphone Addiction Scale – Short Version (SAS-SV) and examined its associated sociodemographic factors and health behaviors in Chinese adults in Hong Kong.

Methods
A random sample of 3,211 adults aged ≥18 years (mean ± SD: 43.3 ± 15.7, 45.3% men) participated in a population-based telephone survey in Hong Kong and completed the Chinese SAS-SV. Multivariable linear regressions examined the associations of sociodemographic factors, health behaviors, and chronic disease status with SAS-SV score. Data were weighted by age, sex, and education attainment distributions of the Hong Kong general population.

Results
The Chinese SAS-SV is internally consistent (Cronbach’s α = .844) and stable over 1 week (intraclass correlation coefficient = .76, p < .001). Confirmatory factor analysis supported a unidimensional structure established by previous studies. The weighted prevalence of PSU was 38.5% (95% confidence interval: 36.9%, 40.2%). Female sex, younger age, being married/cohabitated or divorced/separated (vs. unmarried), and lower education level were associated with a higher SAS-SV score (all ps <.05). Current smoking, weekly to daily alcohol drinking, and physical inactivity predict greater PSU after controlling for sociodemographic factors and mutual adjustment.

Discussion and conclusions
The Chinese SAS-SV was found valid and reliable for assessing PSU in Hong Kong adults. Several sociodemographic and health behavioral factors were associated with PSU at the population level, which may have implication for prevention of PSU and future research.
Forecast of Ugra transport development
Authors: Bolshanik Petr V. 
Published: November 2018

Background: The transport industry is leading in the overall structure of the country's economy. In parts of the regions, this industry can be a branch of specialization.
Aim: To forecast further development of the industry in the territory of Ugra.
Method: Analysis based on a questionnaire survey of organizations related to the transport industry in Ugra.
To analyze the further development of the transport industry of Ugra, the methods of SWOT analysis and rating ranking were used.
Results: The study revealed the main and secondary factors of the transport industry of Ugra. The analysis allowed to determine the strengths and weaknesses of transport, opportunities and threats to its development. On the basis of the analysis three rows of the forecast of transport development are given: pessimistic, moderate and optimistic.
Conclusion: Thus, based on the analysis of the data presented, the following conclusions can be drawn:
First, regional or inter-municipal highways, as well as the federal highway, perform a clearly expressed system-forming, supporting role in the common network of Ugra roads - on 8 km of these roads 8.8 km of private and local roads (for example, in Russia this ratio is 2.8 km);
These roads, in comparison with the average indicators for regional or intermunicipal motorways of Russia, have higher loads, both from single types of motor transport, and the total load from all types of motor transport.
Secondly, measurements of traffic on the bridge over the Ob River in Surgut showed that 44 % of passenger cars and 69 % of trucks, as well as 54 % of buses in the transport stream, consisted of transport from 32 other regions of the country.
Taking into account that Rosstat cites the volumes of cargo transportation by organizations in the place of their registration, it is possible to assume with full justification that the actual volume of transported goods along the roads of Yugra is much larger. Above and the dynamics of growth in the volumes of goods transported by road.
Thirdly, the industrial orientation of economic development predetermines the vastness of economic ties between Ugra and other regions of the country, which places regional inter-regional importance for the main regional roads, and therefore the construction and maintenance of such highways should be carried out not only at the expense of the budget of the Autonomous Okrug, but also of the federal budget.
Service experiences Maglev vehicles Shanghai
Authors: Rampelmann Reinhard , Köhler Reiner 
Published: November 2018

In the late 1990s thyssenkrupp Transrapid GmbH successfully qualified the Maglev Vehicle TR08 and obtained the type approval certificate. Based on that design, in 2001-2003 three five-car vehicles for the first commercial high speed Maglev Line in Shanghai have been manufactured and set into operation. The VIP-Run took place over 15 years ago and the commercial operation has been running for almost 15 years at great availability.
The Transrapid system concept of small autonomous redundant electronics based modules facilitates significantly smooth maintenance - diagnosis, testing and system inspection.
Thanks to intelligent diagnostics, the use of easily interchangeable plug-in units, the dimensioning of the spare parts inventory according to the expected failure rates and the replenishment lead time, the maintenance efforts are still within the forecast range at the beginning of the project. Furthermore, the maintenance concept is essentially unchanged since the beginning.
There are no special materials that are subject to a potential shortage or price leap, but all according to normal industrial base.
Thanks to the low level of stress to components on board, most electrical and electronic units are still on-board as original equipment, which are 15 years old and at no end of life is visible.
But in case of repair or replacement, the challenge is the adaptation to the volatile market of electronic components. This includes the necessary lead-time for adaptive development and qualification, which has to be considered.
On the side of the vehicle supplier, a small smart team of electronics experts is managing obsolescence and compensates discontinuation.
The paper tells how it works and appreciates trustful cooperation of the supplier in Europe with the operator in China.
Volatile compounds of the Lavandula angustifolia Mill. (Lamiaceae) Species Cultured in Turkey
Authors: KÜÇÜK Sevim , ÇETİNTAŞ Esra , KÜRKÇÜOĞLU Mine 
Published: November 2018

The genus Lavandula L. (Lamiaceae) is represented in Turkey by 3 taxa (Lavandula angustifolia Mill. subsp. angustifolia, L. pedunculata (Mill.)
subsp. cariensis (Boiss.), L. stoechas L. subsp. stoechas). L. angustifolia is
locally known as “lavanta”, L.
pedunculata subsp. cariensis is locally known as “karan”, L. stoechas subsp. stoechas . is locally known as “karabaş” ( Mill, 1982; Dirmenci, 2012). Within this family there
are many medical species such as
Lavandula L., Lavandula angustifolia Mill.
known as medical lavender, is conducting culture and research studies in many
places in the world. It is also known as the ‘’English lavender’2 or L. officinalis. Lavender is used in
aromatherapy. Its sedative nature, on inhalation has been shown both in animals
and man. Experimental studies in humans and animals have shown that the
sedative effect comes from linalool and linalyl acetate. Tanins contained in
flowers of lavender is showned antidiarrheal effect. Essential oil of lavender
is used in various skin diseases and wound healing. Essential oil of lavender
shortens the sleeping period, prolongs the sleeping period. In addition, it
also shows antimicrobial, antiinflammatory, fungicidal, insecticidal and
acaricidal effects (Zeybek and Haksel, 2010). In this study, we were made to
create sources Lavandula agriculture in Turkey. We collected four different
provinces in the Lavandula (5 samples
and 1 commercial oil). The results of a total five local and commercial are
given below. The flowers of Lavandula were water distilled for 3 h using a
Clevenger type apparatus.
The essential oils were analyzed by GC and GC-MS simultaneously. The main constituents were identified as linalool 31.9 –
50.0 % and linalyl acetate 15.4 – 42.0 %.
Influence of Process Models on Requirement Volatility, and Strategies for its Management – An Empirical Investigation
Authors: Thakurta Rahul 
Published: November 2018

The current research aims to investigate the preparedness among organizations in managing requirement volatility, and how it is influenced by process factors characterizing a software project. A combination of interviews and survey organized in two phases has been used to assess the level of awareness related to requirement volatility, and the current level of organizational competencies in dealing with the problem. Frameworks regarded suitable for handling volatility has been presented. Factors governing process model selection and usage and their applicability under requirement volatility have also been explored.
Concerns were raised over the high percentage of projects found affected because of requirement volatility. Two widely used approaches for managing projects under volatility were found to be involving the business side and resorting to iterative project development. Difference in usage of the approaches based on process models could be observed. Influence of business/customers, project complexity and managerial preferences emerged as the top three factors guiding process model selection. The variation of these factors under requirement volatility has been pointed out. The results also highlight incongruence between perception and practice related to process model usage in projects endangered because of requirement volatility.
Evaluation of the effectiveness of aprepitant for prevention of nausea and vomiting in patients with breast cancer
Authors: Koroleva I. A. , Kopp M. V. , Koroleva A. M. 
Published: November 2018

Chemotherapy regimen AС (doxorubicin and cyclophosphamide) is the most often used in adjuvant chemotherapy of breast cancer. AC regimen is high emetogenic. Objective – to evaluate the effectiveness of the combination of aprepitant, ondansetron and dexamethasone for the prevention of nausea and vomiting in patients with breast cancer receiving chemotherapy regimen AC. Materials and methods:64 female patients with breast cancer received adjuvant chemotherapy regimen AC: doxorubicin 60 mg/m2, cyclophosphamide 600 mg/m2 in day 1, each 21 day 4 cycle. Patients of Group 1 (n=34) received an triple-therapy regimen ( aprepitant 125 mg p.o. in day 1, 80 mg in days 2 and 3, ondansetron 8 mg i.v. in 1 day, dexamethasone 12 mg i.v.in 1 day, then to 8 mg/day p.o. in days 2–4) for prevention of nausea and vomiting. Patients of Group 2 (n = 30) received ondansetron 8 mg i.v. in 1 day, dexamethasone 12 mg i.v.in 1 day, then to 8 mg/day p.o. in days 2-4). The quality of life of patients was assessed by Functional Living Index of emesis (FLIE). Results: During the first cycle of chemotherapy complete control of nausea and vomiting was achieved at 20 (58,8%) patients of Group 1 and at 4 (13.3%) %) patients of Group 2 (p<0.05). The average score on the Functional Living Index of emesis (FLIE) scale in Group 1 was 19.88, in Group 2-38.03 (p<0.05). Conclusion: Adequate regimen for prevention of nausea and vomiting is combination of NK1 receptor antagonist, 5-HT3 receptor antagonist and dexamethasone.
RECONSIDERING THE THEORY OF THE ENERGY PRODUCTION CYCLES: THE CASE OF KUZBASS COAL PRODUCTION CYCLE
Authors: Шерин Егор , Sherin Egor 
Published: November 2018

The paper considers the theory of energy production cycles. It indicates its relevance and the possibility of successful application for the analysis of the territorial structure and assessment of the prospects for modernization of the economy. At the same time, questions are raised about the inconsistency of this concept with modern market conditions. An attempt is made to rethink the theory of energy production cycles, on the basis of which the concept «coal cycle of productions» is formulated and the author’s generalized scheme of this cycle is given. Next, the research compares a general scheme of the coal production cycle with the production cycle actually formed around Kuznetsk coals. On the basis of this comparison, the degree of completeness and the reserves for further modernization of this cycle of production were revealed. Among the possible directions of coal use, the most promising for introduction in the Kuzbass are indicated, namely: coal semi-coking, gasification (including underground coal) and preparation of water-coal fuel. The research has revealed some positive effects from this complication of the existing coal production cycle in the Kuzbass.