bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematic evaluation of therapeutic effectiveness of Azvudine in treating COVID-19 hospitalized patients: a retrospective cohort study
Authors: Xu Yingkai , Huang Yuan , Yuan Zihan , Liu Wanbing , Wang Li , Liu Lei 
Published: November 2024

BackgroundAzvudine, a repurposed oral small molecule antiviral drug, has potential effects in combating the SARS-CoV-2 virus. However, studies on its clinical efficacy in patients with COVID-19 are still limited and controversial, and further research and validation are necessary.MethodsA retrospective cohort study was conducted on COVID-19 patients who were hospitalized in the General Hospital of Central Theater Command from 1 December 2022 to 31 January 2023. We included 132 patients treated with Azvudine and 132 controls after screening and propensity score matching. The primary outcomes including all-cause mortality and a composite outcome of disease progression such as non-invasive respiratory support, invasive respiratory support, admission to intensive care unit (ICU), and death were compared.ResultsAzvudine recipients had a much lower incidence rate of composite disease progression outcome than controls (13.9075/1000 person-days versus 25.7731/1000 person-days, P&lt;0.05). Azvudine recipients also possessed a lower all-cause mortality rate than controls (2.6797/1000 person-days versus 8.5910/1000 person-days, P&lt;0.01). Azvudine treatment significantly reduced the risk of composite disease progression (HR: 0.37, 95% CI: 0.16-0.84, P=0.017) and all-cause death (HR: 0.25, 95% CI: 0.08-0.81, P=0.021) after adjusting potential confounding factors such as age, sex, severity of COVID-19, complications, concomitant therapy, time from symptoms to treatment, and important laboratory indicators. The subgroup analyses of composite disease progression outcome and all-cause death indicated robustness of Azvudine’s in treating COVID-19 patients in general.ConclusionOur study demonstrates that Azvudine has a significant positive impact on the clinical recovery of hospitalized patients with COVID-19. These findings provide important support for the use of Azvudine as a therapeutic option for COVID-19, given the current divergent views on its therapeutic efficacy and its importance in public health and medical care.
Role of Social Support and Cognitive Emotion Regulation in Mental Health Outcomes of Women Behind Bars
Authors: Maryam Rabia , Khawar Rabia , Mehmmod Syeda  Huma , Hussain Samavia 
Published: November 2024

Purpose:This research was carried out to find the role of social support and cognitive emotion regulation approaches in mental health outcomes of women behind bars.
Method:Female prisoners (n=200) were approached from four district jails of Punjab with purposive sampling technique. Cognitive Emotion Regulation Questionnaire (CERQ; Garnefski, Kraaij & Spinhoven, 2001), General Health Questionnaire- 28 (GHQ-28; Goldberg ,1978) and Multidimensional Scale of Perceived Social Support (MSPSS, Zimet, Dahlem, Zimet & Farley, 1988) were used to measure coping strategies, mental health and communal support provided to female prisoners.
Results: Regression analysis revealed that perception of social support from significant others considerably predicted adaptive cognitive emotion regulation approaches whereas, lack of perceived social support lead towards maladaptive cognitive emotion regulation strategies and poorer mental health outcomes. It was also indicated from the results that somatic symptoms were predominant psychological problem among female prisoners, followed by anxiety insomnia, social dysfunction and severe depression. Limitations and suggestions were also discussed.
Conclusion: This study proved to be a significant addition in forensic psychology and help forensic psychologist to understand mental health problems of female prisoners and to make interventions.
Family Attitude toward Achievement as Predictor of Impostor Phenomenon among students: Role of Narcissism
Authors: Rubab Anam , Malik Sadia , Wajahat Mobina 
Published: November 2024

Background. Impostor is a motivational phenomenon for people who succeed, one’s view other factors attribute to their success such as luck (Feenstra et al., 2020). The present study is to investigate the relationship among family attitude towards achievement, impostor phenomenon and moderating role of narcissism.
Method. A correlation research design was used in present study. Through convenience sampling data was collected from 400 students (Male = 200 and Female = 200). Clance impostor phenomenon scale (Clance, 1987), Mixed Message about Achievement scale (Thompson & Dinnel, 2001) and Narcissism (subscale of short dark triad scale) (Jones & Paulhusin, 2014) were used. A correlation research design was used in present study.
Results. Result indicated that mixed message from family and family achievement values have positive relationship with impostor phenomenon and narcissism. On other hand, mixed message from family, family achievement values and narcissism positively predict impostor. Further results indicated narcissism not moderate between mixed message from family, family achievement values and impostor phenomenon.
Conclusion. Finding indicates family attitude toward achievement more prone to develop impostor feelings and narcissism personality. Hence, in present age there is dire need to create awareness about the importance of family attitude related to achievement and impostor phenomenon. This research is also beneficial in clinical and academic setting to do further research and develop psychotherapy.
Keywords. Family attitude toward achievements, narcissism, impostor phenomenon
A importância do cirurgião-dentista no âmbito esportivo
Authors: Fortes Júlia Rodrigues de Lima , Calixto Jeovana Carla Ricardo , Barbosa Cayo Lucas Correia de Oliveira , Gomes Ittalo Henrique Santos , Pontes Danilo Barros , Barros José Victor Curvelo , Lima Anniely Hellen Cedro , Macêdo Lucas Fortes Cavalcanti de 
Published: November 2024

Introdução: A odontologia do esporte é uma especialidade que vem atualmente promovendo a interação entre os cuidados de saúde geral com a saúde bucal dos atletas, sendo responsável primordialmente pela atuação em prevenção, diagnóstico e tratamentos das doenças orais em atletas, constituindo-se como uma nova forma de atuação profissional para o cirurgião dentista (Carvalho, 2020). A odontologia esportiva, durante muitos anos ficou sem a devida atenção e geralmente era relegada ao terceiro plano de atenção a saúde dos atletas. Mas hoje a odontologia esportiva vem crescendo de forma tão visível e se mostrando em uma expansão tão grandiosa em comparação a outras especialidades odontológicas (SOUZA, 2014). Metodologia: O trabalho refere-se de uma pesquisa de revisão integrativa de literatura, para identificar a importância dó cirurgião-dentista no âmbito esportivo, a partir de coleta de dados realizados a partir de fontes secundárias, por meio de levantamento bibliográfico, tendo características, descritivas, retrospectiva, com abordagem qualitativa. Conclusão: A odontologia do esporte tem se consolidado como uma especialidade essencial para a manutenção da saúde bucal e o aprimoramento do desempenho dos atletas. Este artigo demonstrou que a saúde oral não apenas afeta a função mastigatória, mas também tem um impacto significativo na performance atlética.
Ectopia testicular transversa: revisão da literatura
Authors: Wanderley Alana Emilly Andrade de Souza , Loureiro Norma Caroline Furtado Montenegro , Souza Ana Paula Maia de 
Published: November 2024

O objetivo deste estudo é realizar uma revisão integrativa da literatura para compreender os achados de imagem nos diferentes métodos de diagnóstico utilizados na ectopia testicular transversa. A metodologia se caracteriza como uma revisão integrativa da literatura. Foram selecionados artigos na base de dados PubMed/MedLine e Scopus, com critérios específicos de inclusão e exclusão, abrangendo o período até 2023 e utilizando descritores: "Transverse Testicular Ectopia" ; "Crossed Testicular Ectopia" e "Diagnosis" ou "Imaging Exams". Como resultados foram encontrados 220 artigos na pesquisa ampla, destes, 25 tinham relação direta com o tema desta revisão, atenderam aos critérios de seleção deste estudo e compuseram a revisão. A revisão abordou métodos de imagem na ectopia testicular transversa, destacando ultrassonografia, tomografia e ressonância magnética. Achados incluem testículos ectópicos em locais anômalos e complicações associadas.Conclui- se que a ectopia testicular transversa, embora rara, é clinicamente relevante, apresentando desafios diagnósticos e terapêuticos. Destaca-se o papel crucial da ultrassonografia, tomografia e ressonância magnética na identificação e caracterização dos testículos ectópicos. Há limitações na disponibilidade de estudos específicos, destacando a necessidade contínua de pesquisa na área.
Elephantiasis and its cure: case report
Authors: Godoy Jose Maria Pereira de , Godoy Henrique Jose Pereira de , Ana Carolina Pereira de Godoy  , Godoy Maria de Fatima Guerreiro 
Published: November 2024

Introduction: Lymphedema is a clinical condition stemming from a lymphatic system failure. The insufficiency of the lymphatic system can causes the abnormal accumulation of protein-rich fluid in the interstitial, which triggers a adverse consequence such a and fibrosis. This study describes a case of a patient who has been cured of elephantiasis for ten years but continues to have lymphedema. Description case: Patient information: A 78-year-old woman had a history of bilateral lower limb lymphedema, clinical diagnosis that had been worsening throughout her life bilateral despite undergoing treatment and had progressed to stage III (elephantiasis). Clinical findings: The patient was sent to the Clínica Godoy-Sao Jose do Rio Preto-Brazil ten years ago and reported having undergone several forms of treatment, but without impeding the progression of the condition. Therapeutic intervention: The patient was submitted to intensive treatment for three weeks, during which time a 21-kilogram reduction in weight and a 66-cm reduction in circumference occurred. After three weeks, the patient began undergoing treatment at home with laced compression stockings. At the follow-up evaluation, electrical bioimpedance analysis, perimeter measurements and volumetry were performed, which revealed the reduction in lymphedema to standards of normality. The patient has completed 10 years of treatment and has maintained the results using compression stockings. Conclusion: Elephantiasis is curable, but lymphedema is not. Like any other chronic disease, constant treatment is needed to maintain the results.
ИННОВАЦИОННАЯ ТЕРАПИЯ РЕВМАТИЧЕСКИХ ЗАБОЛЕВАНИЙ
Authors: Р.Л. Иванова 
Published: November 2024

В статье по результатам международного опыта и собственных исследований представлены современные направления в лечении аутоиммунных ревматических заболеваний с использованием генно-инженерных биологических антицитокиновых препаратов, ингибиторов внутриклеточных ферментов – киназ для лечения по принципу «treat to target». Данные этой статьи будут полезны или интересны для интернов, резидентов и врачей – ревматологов, а также для преподавателей медицинских университетов.
Based on the results of international experience and personal research, the article represents modern methods of treatment of autoimmune rheumatic diseases using genetically-engineered anti-cytokine drugs, inhibitors of intracellular enzyme-kinase for treatment on “treat to target” principle. The article findings will be helpful for interns, residents and rheumatologist physicians, as well as teacher of medical universities.
Мақалада халықаралық тәжірибеге және өз зерттеулеріне негізделген аутоиммунды ревматикалық ауруларды заманауи бағытта емдеудің генетикалық инженерлі биологиялық антицитокиндік препараттарды қолдануы, «мақсатты емдеу» принцип бойынша емдеуге арналған жасушааралық ферменттердің ингибиторлары - киназалар көрсетілген. Осы мақаланың деректері интерндерге, резиденттерге және ревматологтарға, сондай-ақ медициналық жоғары оқу орындарының оқытушыларына пайдалы немесе қызықты болады.
PENGARUH PENYALURAN ZIS DAN PEMBIAYAAN PERBANKAN SYARIAH TERHADAP INDEKS PEMBANGUNAN MANUSIA (IPM) DI INDONESIA
Authors: Firmansyah Herlan , Hertikawati Lilis , Aprilia Ellsa 
Published: November 2024

Penelitian ini dilatarbelakangi oleh IPM Indonesia yang tidak meningkat secara signifikan, mengindikasikan pelaksanaan pembangunan manusia di Indonesia berkembang dengan lambat. Sebagai negara dengan mayoritas masyarakatnya beragama Islam, Indonesia menjadikan penyaluran ZIS dan pembiayaan perbankan syariah sebagai salah satu aspek yang diharapkan dapat meningkatkan kualitas hidup manusia. Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh Penyaluran ZIS dan Pembiayaan Perbankan Syariah terhadap Indeks Pembangunan Manusia (IPM) di Indonesia. Metode penelitian yang digunakan adalah analisis deskriptif dan asosiatif dengan pendekatan kuantitatif. Teknik analisa yang digunakan analisis regresi berganda. Berdasarkan hasil uji statistik t diperoleh terdapat pengaruh signifikan antara penyaluran ZIS terhadap IPM, dengan hasil perhitungan SE X1 menunjukkan adanya kontribusi atau pengaruh variabel penyaluran ZIS terhadap variabel IPM sebesar 62,27%. Hasil uji t pembiayaan perbankan syariah diperoleh pengaruh tidak signifikan antara pembiayaan perbankan syariah terhadap IPM. Kemudian secara simultan kedua variabel berpengaruh signifikan terhadap IPM, diketahui dari nilai uji Fhitung sebesar 4,335 > Ftabel 3,59 dengan nilai R Square sebesar 35,1%, hal ini berarti penyaluran ZIS dan pembiayaan perbankan syariah memberikan kontribusi 35,1% sedangkan sisanya 64,9% merupakan pengaruh faktor lain. This research is motivated by Indonesia's HDI which has not increased significantly, indicating that the implementation of human development in Indonesia is developing slowly. As a country with a majority Muslim population, Indonesia makes the distribution of ZIS and sharia banking financing one of the aspects that are expected to improve the quality of human life. This research aims to find out how big is the influence of ZIS Distribution and Sharia Banking Financing on the Human Development Index (HDI) in Indonesia. The research method used is descriptive and associative analysis with a quantitative approach. The analysis techniques is multiple regression analysis. Based on the results of the t statistical test, it was found that there was a significant influence between ZIS distribution on HDI, with the SE X1 calculation results showing that there was a contribution or influence of the ZIS distribution variable on the HDI variable of 62.27%. The results of the t test for sharia banking financing showed that there was no significant effect between sharia banking financing on HDI. Then simultaneously both variables have a significant effect on HDI, it is known from the Fcount test value of 4.335 > Ftable 3.59 with an R Square value of 35.1%, this means that ZIS distribution and sharia banking financing contribute 35.1% while the remaining 64 .9% is the influence of other factors.
Implementasi Value Stream Mapping dalam Optimalisasi Proses Bisnis: Tinjauan Pustaka
Authors: Herlianti Rosi , Hasbullah Hasbullah 
Published: November 2024

Lean is a problem-solving approach that focuses on eliminating waste. One of the tools used in Lean is Value Stream Mapping (VSM). VSM is an effective tool in improving operational efficiency and quality in various sectors, both manufacturing and services. However, the application of VSM has not been widely implemented in testing laboratories. Therefore, this paper aims to explore the application of VSM in testing laboratories. The analysis was carried out based on the definition, objectives, benefits, and application of VSM, especially in the context of testing laboratories. Through the screening stage using the PRISMA method, there were 30 articles that were closely related to the application of VSM. The paper found that VSM helps identify and eliminate waste in the testing process, reduces cycle time, and improves the quality of results. In addition, VSM also supports sustainability by reducing resource use and environmental impacts. In conclusion, VSM is a very useful tool for testing laboratories to achieve increased efficiency, quality, and sustainability. Future developments include integrating the VSM-based Lean approach with digitalization. Lean merupakan salah satu pendekatan pemecahan masalah yang berfokus pada eliminasi pemborosan. Salah satu alat yang digunakan dalam Lean adalah Value Stream Mapping (VSM). VSM merupakan alat yang efektif dalam meningkatkan efisiensi dan kualitas operasional di berbagai sektor, baik manufaktur maupun jasa. Namun, penerapan VSM sampai saat ini belum banyak dilakukan di laboratorium pengujian. Oleh karena itu makalah ini bertujuan untuk mengeksplorasi penerapan VSM di laboratorium pengujian. Analisis dilakukan berdasarkan definisi, tujuan, manfaat, dan penerapan VSM khususnya dalam konteks laboratorium pengujian. Melalui tahapan penyaringan dengan metode PRISMA, terdapatlah 30 artikel yang sangat berkaitan dengan penerapan VSM. Makalah menemukan bahwa VSM membantu mengidentifikasi dan mengeliminasi pemborosan dalam proses pengujian, mengurangi waktu siklus, dan meningkatkan kualitas hasil. Selain itu, VSM juga mendukung keberlanjutan dengan mengurangi penggunaan sumber daya dan dampak lingkungan. Kesimpulannya, VSM adalah alat yang sangat bermanfaat bagi laboratorium pengujian untuk mencapai peningkatan efisiensi, kualitas, dan keberlanjutan. Pengembangan ke depannya melakukan integrasi pendekatan Lean berbasis VSM dengan digitalisasi.
Hubungan antara Motivasi Belajar dengan Self Directed Learning Readiness pada Mahasiswa Tahun Pertama Fakultas Kedokteran Universitas Sam Ratulangi
Authors: Ngongoloy Johanes J. F. , Berhimpon Siemona , Pangemanan Damajanty 
Published: November 2024

Abstract: Learning methods of Student Centered Learning indirectly demand students to study independently. Self-directed learning readiness (SDLR) or the readiness of students to the independence learning is something that medical students must have. Self-directed learning readiness is influenced by several factors, one of them is motivation to learn. This study aimed to determine the relationship between learning motivation and SDLR of first year students at the Faculty of Medicine, Universitas Sam Ratulangi. This was an observational and analytical study using a cross-sectional design. There were two types of questionnaires which were the motivated strategies for learning questionnaire (MSLQ) to assess learning motivation and the self-directed learning readiness scale (SDLRS) to assess readiness for independent learning. The Spearman test showed that there was a significant relationship between learning motivation and SDLR (p-value=0.000), with a strong and positive correlation (r=0.557) among the first-year students of Faculty of Medicine Universitas Sam Ratulangi. In conclusion, there is a significant relationship between learning motivation and self-directed learning readiness (SDLR) with a strong and positive correlation.
Keywords: medical students; learning motivation; learning methods

Abstrak: Metode pembelajaran Student Centered Learning secara tidak langsung menuntut mahasiswa untuk belajar secara mandiri. Self-directed learning readiness (SDLR) atau kesiapan belajar mandiri merupakan hal yang harus dimiliki mahasiswa fakultas kedokteran. Tingkat SDLR dipengaruhi oleh beberapa faktor, salah satunya ialah motivasi belajar. Penelitian ini bertujuan untuk mengetahui hubungan antara motivasi belajar dengan SDLR mahasiswa tahun pertama Fakultas Kedokteran Universitas Sam Ratulangi. Jenis penelitian ialah observasional analitik dengan desain potong lintang. Terdapat dua jenis kuisioner yang digunakan yaitu Motivated Strategies for Learning Questionnaire (MSLQ) untuk menilai motivasi belajar dan Self Directed Learning Readiness Scale (SDLRS) untuk menilai kesiapan belajar mandiri. Hasil analisis data menggunakan uji korelasi Spearman menunjukkan bahwa terdapat hubungan bermakna antara motivasi belajar dan SDLR (p=0,000), kekuatan korelasi kuat (r=0,557), dan hubungannya berpola positif yang berarti semakin tinggi motivasi belajar maka akan semakin tinggi juga tingkat SDLR. Simpulan penelitian ini ialah terdapat hubungan bermakna antara motivasi belajar dan self-directed learning readiness (SDLR) dengan tingkat keeratan kuat dan memiliki arah positif.
Kata kunci: mahasiswa kedokteran; motivasi belajar; metode pembelajaran
Non-destructive orientation mapping of die-attach lead-free solder
Authors: Hayashi Yujiro , Kimura Hidehiko 
Published: November 2024

Abstract
Thermo-mechanical fatigue poses a serious challenge to the electrical operation of power semiconductor modules, manifested by the degradation of die-attach lead-free solder. So far, orientation microscopy (OM) using electron backscatter diffraction is considered a sensitive approach to characterizing the degradation of solder. However, its destructive character inhibits assessing solder inside the power modules. We propose a non-destructive OM method based on X-ray diffraction and successfully observed the changes in the orientation of the solder caused by thermo-mechanical fatigue. The proposed non-destructive OM method can facilitate the development of reliable power modules by evaluating the degradation of the solder inside the power modules.
Gysinite-(Ce), PbCe(CO3)2(OH)(H2O), a New Member of the Ancylite Group
Authors: Kampf Anthony R. , Möhn Gerhard , Ma Chi , Désor Joy , Groß Manfred 
Published: November 2024

Abstract
The new mineral gysinite-(Ce), PbCe(CO3)2(OH)(H2O) (IMA2023-035), was found at the Abendröthe Mine, St. Andreasberg, Braunlage, Goslar district, Lower Saxony, Germany, where it occurs in a single vug in association with albite, calcite, and mimetite. It is a secondary oxidation-zone mineral presumably crystallized from hydrothermal solutions. Gysinite-(Ce) occurs in intergrowths of equant pseudo-octahedral crystals, up to about 0.7 mm in maximum dimension. The color is brownish yellow, the streak is pale yellow, and the luster is vitreous to subadamantine. The mineral is brittle with curved, irregular fracture and no cleavage. The Mohs hardness is about 3½. The calculated density is 5.136 g/cm3. The mineral is biaxial (−) with α = 1.750(5), β = 1.825(5), γ = 1.860(5). The 2V is 65.1(4)° with no observable dispersion. The optical orientation is X = c; Y = a; Z = b by analogy with gysinite-(Nd) and there is no pleochroism. Electron probe microanalyses provided the empirical formula (Pb0.930Ce0.434La0.349Nd0.196Pr0.048Gd0.037Sm0.007)Σ2.000(CO3)2(OH)1.074(H2O)0.926. Gysinite-(Ce) is orthorhombic, Pmcn, a = 5.0780(4), b = 8.6689(6), c = 7.3255(6) Å, V = 322.47(4) Å3, and Z = 2. Gysinite-(Ce) is isostructural with gysinite-(La), gysinite-(Nd), and other members of the ancylite group. The crystal structure (R1 = 0.0268 for 396 I &gt; 2σI) is a framework consisting of edge-sharing (PbCe)O8(OH)(H2O) polyhedra and CO3 triangles.