bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Medication Beliefs, Self-efficacy, and Adherence in a Diverse Cohort of Adults with Rheumatoid Arthritis
Authors: McCulley Caroline , Katz Patricia , Trupin Laura , Yelin Edward H. , Barton Jennifer L. 
Published: September 2018

Objective.Rheumatoid arthritis (RA) patients’ adherence to disease-modifying antirheumatic drugs (DMARD) is often suboptimal. We examined associations among medication beliefs, self-efficacy, and adherence to medications in RA.Methods.Data were from a longitudinal observational cohort of persons with RA. Subjects completed telephone interviews on self-reported adherence, self-efficacy, demographics, and the Beliefs about Medicines Questionnaire (BMQ), which assesses beliefs in necessity and beliefs about taking medication. Bivariate and multivariate logistic regression identified correlates of poor adherence to synthetic DMARD and prednisone as well as to biologic therapy, including medication concerns and necessity.Results.There were 362 patients who reported taking a synthetic DMARD and/or prednisone. Of these, 14% and 21% reported poor adherence to oral DMARD or prednisone, and biologics, respectively. There were 64% who reported concern about taking medicines, 81% about longterm effects, and 47% about becoming too dependent on medicines. In multivariate analyses, the BMQ necessity score was independently associated with better adherence to oral DMARD or prednisone (adjusted OR 0.61, 95% CI 0.41–0.91), while self-efficacy was associated with greater odds of poor adherence to oral medications (adjusted OR 1.23, 95% CI 1.01–1.59). Beliefs in medicines and self-efficacy were not associated with adherence to biologics.Conclusion.In a diverse cohort of patients with RA, stronger beliefs in the necessity of medication were associated with better adherence to oral DMARD or prednisone, while higher self-efficacy was associated with poor adherence. Providers can play important roles in eliciting patient beliefs about medications to improve adherence and ultimately health outcomes.
Cinéma et audiovisuel en Côte d’Ivoire (2002-2018)
Authors: Boni Assié Jean-Baptiste 
Published: September 2018

Si la majorité des films ivoiriens est destinée à la télévision, des réalisateurs visent à convertir leur production pour le grand écran. Ces productions, prisées du public, sont réalisées dans un contexte sociétal particulier. En 2008, en effet, ont été créés l’Office national du cinéma de Côte d’Ivoire et le Fonds de soutien à l’industrie cinématographique. Mais si la politique du ministère ivoirien de la Culture fait sens, elle n’en demeure pas moins tâtonnante et inaboutie. Résultat : un regard hâtif aurait tôt fait de conclure à l’immobilisme et même au recul de la production cinématographique en termes de quantité et de qualité. Pourtant, des films de bonne facture voient le jour, dans un univers dominé par le télévisuel. Cet essai dresse un état des lieux de la production cinématographique ivoirienne de 2000 à 2018.
Donnie Yen's star persona in amateur-produced videos on YouTube
Authors: Lau Dorothy 
Published: September 2018

Amateur-produced, web-based videos have become an emergent locus of emulating, multiplying, and reinventing the appeal of martial arts stars, which was once a product of professionals of industrial mechanism. The constellation of user-generated practices on platforms such as YouTube, Twitter, Wikipedia, and Facebook that depend on amateur content has become a vital force driving popular construction that blurs the line between the professional and the amateur. Celebrated transnational Chinese actor Donnie Yen, who has gained huge fame thanks to his work in martial arts hits, was cast in the Star Wars feature Rogue One (2016). An analysis of two videos on YouTube that (re)narrativize Yen's persona in Rogue One shows how video makers working outside the film industry open up new aspects of articulating and understanding the star. Amateur video producers unsettle Yen's status, which is principally anchored on his martial authenticity and acrobatic skills, by either mixing the active body with other generic components like sci-fi or virtualizing the warrior figure in other media contexts, such as video games and virtual reality. The outcome is a composite, multidirectional intertext that engenders novel dimensions of a star text, negotiating and refashioning the martial arts personality. Digital creative texts have discursive power that changes and challenges the industrial structure of cultural production in a volatile media environment.
Fan film on the final frontier: Axanar Productions and the limits of fair use in the digital age
Authors: Lerner Sarah Elizabeth 
Published: September 2018

In an analysis of the copyright case Paramount/CBS v. Axanar Productions Inc. and Alec Peters (2016), which centers on a high-budget Star Trek fan film, I consider how the case frames digital-age media fandom's challenges to the law, and concomitantly, how the case frames the law's challenges to media fandom. Even while legal action of this kind does not dampen participatory culture on the whole, it raises questions about the legal definition of a fan and the limits of fair use doctrine, and it delineates the changing relationships between media industries and fans. Paramount/CBS v. Axanar Productions reveals the tension between the gift-giving ethos of fandom and online crowdfunding as a type of gift; it also reveals the negative industrial and legal reactions to fan filmmaking and crowdfunding as threats to the way film has traditionally been constituted. I analyze Axanar's use of Kickstarter and Indiegogo campaigns, the introduction of Paramount/CBS's restrictive fan film guidelines, and finally, the rejected fair use argument proposed by the defense. I take up the rejected fair use argument by situating it alongside the case history of appropriation art in order to consider another way to argue for fan films as transformative works.
Guerre, guerre civile, guerre révolutionnaire : la violence en héritage dans l'Italie républicaine, 1945-1980
Authors: Cirefice Virgile , Quang Grégoire Le 
Published: September 2018

La fin du deuxième conflit mondial est pour l'Italie une étape clé qui met un terme à deux décennies de fascisme, couronnées par un épisode de violences fratricide à la signification multiple : guerre de libération, guerre civile et, en partie, guerre de classe. Si la compréhension de la nature du totalitarisme fasciste et de la guerre civile a été profondément renouvelée par l'historiographie récente, la portée de cet héritage conflictuel sur le long terme est un terrain d'étude seulement partiellement défriché. C'est d'abord la question des modalités du retour à la paix qui se posent, entre épuration limitée et contestation parfois radicale de l'ordre démocratique mis en place à la Libération. Le processus de transition démocratique est en effet menacé par la permanence de formes de violences politiques et par des rhétoriques de criminalisation de l'ennemi qui se renforcent avec l'entrée en Guerre froide, mais continuent de puiser largement dans les modèles et les cultures politiques héritées de la période de guerre. Au cours des années 1960 puis 1970, la rhétorique anticommuniste et la résurgence d'un antifascisme de combat contribuent également à dramatiser les oppositions politiques, et ce jusqu'aux violences de matrices terroristes qui culminent à la fin des années 1970. En résulte un brouillage persistant entre guerre et paix dans la péninsule italienne qui permet d'interroger sur plus de trois décennies l’héritage de la guerre mondiale.
La violence politique dans le périodique satirique Simplicisssimus de l’avant à l’après Première Guerre mondiale
Authors: Cohen-Avenel Pascale 
Published: September 2018

La violence politique est particulièrement présente entre 1919 et 1923 dans Simplicissimus, qui fut la revue satirique la plus célèbre et la plus brillante d’Allemagne au début du XXe siècle. Cette violence caractérise avant tout les caricatures sur l’occupation des bords du Rhin, puis de la Ruhr, par les troupes françaises d’Afrique, sur le référendum d’autodétermination en Silésie, mais aussi sur la révolution de 1918, les affrontements entre partis et les putschs avortés de 1920 et 1923, ainsi que sur les guerres dans le reste du monde, en particulier entre la Chine et le Japon. Cependant ces images renvoient largement à des représentations de la violence antérieures à la Première Guerre mondiale : en Allemagne, du fait de l’oppression du pays par la Prusse, à l’étranger avec les guerres des Balkans. Si la violence nait de la guerre, la Première Guerre mondiale n’en est qu’un avatar parmi d’autres. Dans le cas des expressionnistes allemands, la confrontation directe avec la guerre marque au contraire le coup d’arrêt de leur fascination pour la violence.
Republication: Conservative Management of Skeletal Class II Malocclusion with Gummy Smile, Deep Bite, and a Palatally Impacted Maxillary Canine
Authors: Wong Ariel , Chang Chris , Eugene Roberts W. 
Published: September 2018

A 21-year-old female presented with chief complaints of crooked teeth, canine impaction, deep bite, and “gummy smile” (excessive maxillary gingival exposure when smiling). Increased facial convexity (15.5°), increased lower facial height (56%), and incompetent protrusive lips (E-line to upper left 2 mm, E-line to lower left 2 mm) were associated with a severe Class II malocclusion (nearly a full cusp bilaterally). There was 7.5 mm of overjet, 100% anterior deepbite, and a left posterior buccal crossbite. Cephalometrics revealed a skeletal discrepancy due to a protrusive maxilla and a retrusive mandible (SNA 85°, SNB 78°, and ANB 7°). Cone-beam computed tomography imaging revealed a palatally impacted right maxillary canine (UR3) near to the adjacent lateral incisor (UR2). The retained right primary canine (URc) was extracted. A simplified open-window technique was utilized to surgically expose its impacted successor. A maxillary anterior mini-screw provided anchorage to align the UR3 in its correct anatomical position. Nonextraction treatment with a passive self-ligating fixed appliance was indicated to align and level both arches. Anchorage provided by infrazygomatic crest bone screws, and maxillary anterior miniscrews were used for the correction of Class II malocclusion and gummy smile. To achieve more esthetic crown lengths in the maxillary anterior segment, gingivectomy was performed with a diode laser 2 months after fixed appliances were removed. This challenging skeletal Class II malocclusion with a Discrepancy Index of 38 was treated in 32 months to excellent outcomes: Cast-radiograph evaluation score of 25 and an pink and white dental esthetic score of 2. All facial and dental corrections were stable at the 6 months follow-up evaluation (Int J Orthod Implantol 2017;48:24-46).
Republished with permission from: Ariel Wong, Chang CH, Roberts WE. Conservative Management of Skeletal Class II Malocclusion with Gummy Smile, Deep Bite, and a Palatally Impacted Maxillary Canine. Int J Orthod Implantol 2017;48:24-46.
ADHESIVE FRICTION BEHAVIOR OF ROUGH RUBBER SURFACES SLIDING AGAINST SMOOTH RIGID SURFACES
Authors: Devalba David Stratford , Thomas Alan G. , Busfield James J. C. 
Published: September 2018

ABSTRACT
A model for the characterization and prediction of the adhesional friction experienced by a rough rubber surface sliding against a smooth rigid surface using fracture mechanics based peeling behavior is supported by experimental results. The friction is characterized by the strain energy release rate associated with the unpeeling of the asperities. This peeling energy of the rubber and rigid surface interface is used to derive a general relation for the frictional shear stress. Peeling characteristics are first found using rolling experiments, then this information is used to predict the results of sliding experiments. The velocity dependence of the friction is explained by relation to the dynamic viscoelastic properties of the rubber. The experiments compare favorably with the theoretical prediction derived using the model.
EFFECTS OF 4,4′-BISMALEIMIDODIPHENYLMETHANE CURING AGENT ON MORPHOLOGICAL, RHEOLOGICAL, AND MECHANICAL PROPERTIES OF DYNAMICALLY VULCANIZED BIIR/POLYPROPYLENE ELASTOMERS
Authors: Wang Fang , Zhang Aiming , Zhou Tao 
Published: September 2018

ABSTRACT
The morphological, rheological, and mechanical properties of BIIR/polypropylene (PP) blends with various amounts of 4,4′-bismaleimidodiphenylmethane (BMI) curing agent were studied. As the level of BMI curing agent increased, the rubber single particle size decreased, but the interaction among the particles strengthened to form aggregates. The rheological properties were determined with a high-pressure capillary rheometer and a rotational rheometer. It was found that the rheological behavior was affected by both the BMI content and the morphology of the blends. The increased BMI content led to the smaller vulcanized BIIR rubber particles dispersing in the PP continuous phase because of the improvement in cross-linking speed and degree as well as the viscosity of BIIR. The dynamic vulcanization strongly improved the elasticity of the blends. The storage modulus, loss modulus, and complex viscosity of cured BIIR/PP blends were all obviously higher than those of the uncured blend, whereas the values of tan δ showed the opposite trend. The as-prepared BIIR/PP thermoplastic vulcanizate exhibited suitable hardness and good mechanical properties.
The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo
Authors: Yu Ming , Wang Hao , Liu Jianwei , Qin Huamin , Liu Shuai , Yan Qiu 
Published: September 2018

The receptive uterine endometrium specifically expresses certain glycosyltransferases, and the corresponding oligosaccharides play important roles in accepting the embryo. The sialyltransferase β‐galactoside‐α2,3‐sialyltransferase III (ST3Gal3) is the key enzyme responsible for sialyl Lewis X (sLeX) oligosaccharide biosynthesis, but the expression and function of ST3Gal3 in the receptive endometrium is still elusive. Here, we found that human endometrial tissues at secretory phase expressed a 4‐fold higher ST3Gal3 level relative to the tissues at proliferative phase. Meanwhile, downregulation of ST3Gal3 or sLeX epitope blockage significantly impaired the receptive ability of human endometrial RL95‐2 cells to trophoblastic cells in vitro and inhibited implantation in pregnant mice. This study suggests that ST3Gal3 facilitates endometrial receptivity through increasing sLeX oligosaccharide, which gives a better understanding of the glycobiology of implantation.
Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations
Authors: Macheleidt Iris F. , Dalvi Priya S. , Lim So‐Young , Meemboor Sonja , Meder Lydia , Käsgen Olivia , Müller Marion , Kleemann Karolin , Wang Lingyu , Nürnberg Peter , Rüsseler Vanessa , Schäfer Stephan C. , Mahabir Esther , Büttner Reinhard , Odenthal Margarete 
Published: September 2018

Lung adenocarcinoma (LUAD) is the most prevalent subtype of non‐small cell lung cancer. Despite the development of novel targeted and immune therapies, the 5‐year survival rate is still only 21%, indicating the need for more efficient treatment regimens. Lysine‐specific demethylase 1 (LSD1) is an epigenetic eraser that modifies histone 3 methylation status, and is highly overexpressed in LUAD. Using representative human cell culture systems and two autochthonous transgenic mouse models, we investigated inhibition of LSD1 as a novel therapeutic option for treating LUAD. The reversible LSD1 inhibitor HCI‐2509 significantly reduced cell growth with an IC50 of 0.3–5 μmin vitro, which was linked to an enhancement of histone 3 lysine methylation. Most importantly, growth arrest, as well as inhibition of the invasion capacities, was independent of the underlying driver mutations. Subsequent expression profiling revealed that the cell cycle and replication machinery were prominently affected after LSD1 inhibition. In addition, our data provide evidence that LSD1 blockade significantly interferes with EGFR downstream signaling. Finally, our in vitro results were confirmed by preclinical therapeutic approaches, including the use of two autochthonous transgenic LUAD mouse models driven by either EGFR or KRAS mutations. Importantly, LSD1 inhibition resulted in significantly lower tumor formation and a strong reduction in tumor progression, which were independent of the underlying mutational background of the mouse models. Hence, our findings provide substantial evidence indicating that tumor growth of LUAD can be markedly decreased by HCI‐2509 treatment, suggesting its use as a single agent maintenance therapy or combined therapeutical application in novel concerted drug approaches.
Clutch Wet
Authors: Fujii Yuji , Kapas Nimrod , Tseng Jau‐Wen 
Published: September 2018

AbstractA wet clutch, which is a type of an oil‐lubricated friction device, is widely utilized in contemporary drivetrain systems as a torque‐transmission or torque‐holding device. It is most commonly employed in a planetary gear‐based automatic transmission as a means to alter torque paths for automated gear ratio changing. A wet clutch is also found as a vehicle launch device in a lay shaft automatic transmission, as a torque split device in a torque transfer case, and, most recently, as a torque‐coupling device in a gasoline‐electric hybrid drive. Although the wet clutch technology has been around over 100 years, its design continues to evolve even today to meet ever‐demanding challenges in fuel economy improvement, drivability enhancement, and shift quality refinement. This chapter describes a wet clutch structure, components, construction materials, and key geometric features. The operating mechanisms and characteristics are presented in details for open clutch, engagement, and release processes. A clutch design process and evaluation methods are discussed in relation to fuel economy, automatic shift quality, and durability requirements. This chapter is concluded with a summary of future trends in wet clutch technologies.
Phenotypic expansion in DDX3X – a common cause of intellectual disability in females
Authors: Wang Xia , Posey Jennifer E. , Rosenfeld Jill A. , Bacino Carlos A. , Scaglia Fernando , Immken LaDonna , Harris Jill M. , Hickey Scott E. , Mosher Theresa M. , Slavotinek Anne , Zhang Jing , Beuten Joke , Leduc Magalie S. , He Weimin , Vetrini Francesco , Walkiewicz Magdalena A. , Bi Weimin , Xiao Rui , Liu Pengfei , Shao Yunru , Gezdirici Alper , Gulec Elif Y. , Jiang Yunyun , Darilek Sandra A. , Hansen Adam W. , Khayat Michael M. , Pehlivan Davut , Piard Juliette , Muzny Donna M. , Hanchard Neil , Belmont John W. , Van Maldergem Lionel , Gibbs Richard A. , Eldomery Mohammad K. , Akdemir Zeynep C. , Adesina Adekunle M. , Chen Shan , Lee Yi‐Chien ,   Undiagnosed Diseases Network, Lee Brendan , Lupski James R. , Eng Christine M. , Xia Fan , Yang Yaping , Graham Brett H. , Moretti Paolo 
Published: September 2018

AbstractDe novo variants in DDX3X account for 1–3% of unexplained intellectual disability (ID) cases and are amongst the most common causes of ID especially in females. Forty‐seven patients (44 females, 3 males) have been described. We identified 31 additional individuals carrying 29 unique DDX3X variants, including 30 postnatal individuals with complex clinical presentations of developmental delay or ID, and one fetus with abnormal ultrasound findings. Rare or novel phenotypes observed include respiratory problems, congenital heart disease, skeletal muscle mitochondrial DNA depletion, and late‐onset neurologic decline. Our findings expand the spectrum of DNA variants and phenotypes associated with DDX3X disorders.
The influence of mindfulness on young adolescents' eyewitness memory and suggestibility
Authors: Qi Hongyuan , Zhang Huan Huan , Hanceroglu Lerna , Caggianiello Julia , Roberts Kim P. 
Published: September 2018

AbstractRecent research has linked mindfulness to adults' false memory formation. This study investigated the effects of mindfulness on adolescents' event memory and suggestibility by using an “extensive” 8‐week mindfulness program, an active control group, and a participatory to‐be‐remembered event. Students aged 13 to 14 were randomly assigned to a mindfulness or active control condition (socioemotional learning). After the seventh week, students participated in a target event and were immediately interviewed during which misleading information was presented. A week later, those in the mindfulness condition incorrectly reported more false information compared with those in the control group. Mindful practice did not affect memory encoding but had a negative effect during retention and retrieval. These findings suggest that adolescents who are exposed to mindfulness exercises may be susceptible to memory intrusions. Professionals should therefore be especially careful to avoid using suggestive and leading questions during investigative interviews with mindful adolescents.
Modular Antigen‐Specific T‐cell Biofactories for Calibrated In Vivo Synthesis of Engineered Proteins
Authors: Repellin Claire E. , Patel Puja , Beviglia Lucia , Javitz Harold , Sambucetti Lidia , Bhatnagar Parijat 
Published: September 2018

AbstractAn artificial cell‐signaling pathway is developed that capitalizes on the T‐cell's innate extravasation ability and transforms it into a vector (T‐cell Biofactory) for synthesizing calibrated amounts of engineered proteins in vivo. The modularity of this pathway enables reprogramming of the T‐cell Biofactory to target biomarkers on different disease cells, e.g. cancer, viral infections, autoimmune disorders. It can be expected that the T‐cell Biofactory leads to a “living drug” that extravasates to the disease sites, assesses the disease burden, synthesizes the calibrated amount of engineered therapeutic proteins upon stimulation by the diseased cells, and reduces targeting of normal cells.
Recent Progress in Rechargeable Potassium Batteries
Authors: Hwang Jang‐Yeon , Myung Seung‐Taek , Sun Yang‐Kook 
Published: September 2018

AbstractThe topic of sustainable and eco‐friendly energy storage technologies is an issue of global significance. To date, this heavy burden is solely addressed by lithium‐ion battery technology. However, the ongoing depletion of limited global lithium resources has restricted their future availability for Li‐ion battery technology, and hence, a significant price increase is expected. This grim situation is the driving force for the development of the “beyond Li‐ion battery” strategy involving alternatives that have several advantages over conventional Li‐ion batteries in terms of cost, durability, safety, and sustainability. Potassium, the closest neighboring alkali element after sodium, offers some unique advantages over lithium and sodium as a charge carrier in rechargeable batteries. Potassium intercalation chemistry in potassium‐ion batteries (KIBs) is successfully demonstrated to be compatible with Li‐ion batteries and sodium‐ion batteries. In addition to KIBs, potassium–sulfur and potassium–oxygen batteries have emerged as new energy‐storage systems due to their low costs and high specific energy densities. This review covers the key technological developments and scientific challenges for a broad range of rechargeable potassium batteries, while also providing valuable insight into the scientific and practical issues concerning the development of potassium‐based rechargeable batteries.