bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alternative Treatment of a Bleeding Rectal Varix Using an Over-the-Scope Clip
Authors: Sánchez-Luna Sergio A. , Gulati Rishabh , Rustagi Tarun 
Published: September 2019

ABSTRACT
Portal hypertension with the subsequent development of portosystemic shunts such as rectal varices is a well-known complication of liver cirrhosis. We discuss the classic options for management of bleeding rectal varices. We present an alternative and not previously described use of an over-the-scope clip to manage bleeding from a rectal varix refractory to management with endoscopic banding.
OSTEOPOROSIS TREATMENT ADHERENCE: RESULTS FROM A RETROSPECTIVE COHORT STUDY
Authors: Nikitinskaya O. A. , Toroptsova N. V. , Nasonov E. L. 
Published: September 2019

Treatment adherence in patients with osteoporosis (OP) is rather low throughout the world, and 50 to 75% of patients stop taking anti-osteoporotic drugs within a year after therapy prescription.Objective: to establish determinants that affect patient adherence to OP therapy.Subjects and methods. The investigation enrolled 150 women older than 50 years (mean age, 68.8±9.4 years) with OP duration of ≥3 years who had made an outpatient visit to the V.A. Nasonova Research Institute of Rheumatology. Their examination consisted of a survey using a specially designed questionnaire. Treatment adherence was evaluated, by using the data on the duration of treatment for OP within 3 years prior to the study inclusion, as well as by calculating the drug use index.Results and discussion.During 3 years, 94 (63%) female patients were adherent to OP treatment, including those who took zoledronic acid (78%), denosumab (75%), and alendronate or ibandronate (60%); therapy with antiosteoporotic drugs was changed in 53% of patients. The most common reason for missing or discontinuing treatment was poor drug tolerance (33%); and that for self-replacement of recommended drugs was their cost (75%). Age, education, marital status, income, duration of disease and length of treatment, a familial history of fractures or a hip fracture, the number of concomitant diseases, and the total number of drugs taken did not affect medication adherence. Patients who were more adherent to OP treatment were those who underwent determination of serum vitamin D levels (p=0.009), calculation of a 10-year absolute osteoporotic fracture risk according to the FRAX® algorithm (p=0.022), an annual bone densitometry examination (p=0.0158) and, more often than annually, biochemical blood tests (p=0.0043), as well as those who had visited their physician 3 times or more during the estimated period (p=0.003). There were more people adherent to OP treatment among the patients receiving the parenteral formulations of drugs than among those who took drugs as tablets (p=0.036). Educational materials, brochures, and lectures on OP and a follow-up in a specialized center did not ensure that treatment adherence could be significantly increased (p>0.05).Conclusion. Patient adherence to OP therapy is positively influenced by determination of serum vitamin D levels, calculation of a 10-year absolute osteoporotic fracture risk (FRAX®), annual therapeutic monitoring using bone densitometry and results of biochemical blood tests, regular visits to a physician who follows up the patient for OP, as well as simplification of a dosing regimen and administration of the parenteral formulations of drugs used to treat OP.
COMPARATIVE ANALYSIS OF MAIN CLINICAL MANIFESTATIONS IN MALES AND FEMALES WITH EARLY AXIAL SPONDYLOARTHRITIS
Authors: Rumyantseva D. G. , Dubinina T. V. , Demina A. B. , Smirnov A. V. , Erdes Sh. 
Published: September 2019

Currently, there have been a small number of works on differences between males and females with axial spondyloarthritis (axSpA) and there have been no studies estimating a gender difference in radiographic sacroiliitis progression in axSpA.Objective: to compare the main clinical manifestations of sacroiliitis and its radiological progression in axSpA in men and women over time during a 2-year follow-up period.Subjects and methods. The investigation was conducted using the Moscow cohort from the early SpondyloArthritis (CoRSAr) study, which currently consisted of 175 patients. The analysis included 68 patients followed up for ≥2 years. Their mean age at the time of inclusion in the cohort was 28.5±5.8 years; the mean disease duration was 24.1±15.4 months. 92.6% of patients were HLA-B27-positive.Results and discussion. Among the 68 patients followed up over 2 years, there were 33 (48.5%) men and 35 (51.5%) women. At baseline, the females were older than the males (p<0.01), while the disease duration was the same and averaged about 2 years. Among the males, there were more patients with ankylosing spondylitis (AS) than those among the females (75.5 and 42.8%, respectively; p<0.05), and the men had a higher total score of radiological sacroiliitis (tsrSI) than the women. The level of C-reactive protein (CRP) was also higher in the men than in the women (12.8 and 4.3 mg/l, respectively; p<0.05). Two years later, AS was present in 90.9% of the males and in 60.0% of the females (p<0.05).Conclusion. Women fall ill with axSpA later than men, and the latter are more frequently observed to have HLA-B27, higher tsrSI and elevated CRP levels. Progression from non-radiological axSpa to AS was more common in men.
ENDOTHELIAL DYSFUNCTION AND NEUROHUMORAL REGULATION OF BLOOD PRESSURE IN PATIENTS WITH SYSTEMIC SCLEROSIS
Authors: Shilkina N. P. , Yunonin I. E. , Stolyarova S. A. , Vinogradov A. A. 
Published: September 2019

Objective: to investigate the effect of endothelial dysfunction, catecholamines, and renin on the diurnal blood pressure (BP) profile in patients with systemic sclerosis (SS).Subjects and methods. Twenty-five patients with SS underwent determination of the blood count of desquamated endotheliocytes by the method described by J. Hladovec (1978), the plasma levels of endothelin-1 (ET-1), adrenaline, norepinephrine, and renin by enzyme immunoassay. All the patients underwent 24-hour BP monitoring with calculating the time index, daily index, the magnitude and rate of a morning rise in BP, as well as its daily variability.Results and discussion. Hypertension was detected in 8 (32%) patients with SS. All the patients with SS showed signs of endothelial dysfunction, as evidenced by considerable differences in endothelial activation measures compared with the control group: the mean level of ET-1 was 5.8±2.3 and 0.48±0.21 fmol/ml (p<0.05); the number of desquamated endotheliocytes was 4.50 [3.00; 7.00] and 2.10 [1.00; 3.20] • 104/l, respectively (p<0.05). The levels of adrenaline and norepinephrine in SS were significantly higher than those in the control. There were positive correlations between endothelial dysfunction and the degree of an increase in BP. Endothelial dysfunction was found to have a negative impact on the diurnal BP profile in the presence of pathological types of night-peaker and non-dipper. Conclusion. Two mechanisms, such as endothelial dysfunction and sympathoadrenal activation, are responsible for the pathogenesis of clinical symptoms of SS, including hypertension.
RARE RHEUMATIC DISEASES. RELAPSING POLYCHONDRITIS: A CLINICAL CASE
Authors: Semizarova I. V. , Eliseeva L. N. , Davydova A. F. , Baste Z. A. , Kisian Zh. A. 
Published: September 2019

The diagnosis of a disease accompanied by febrile syndrome presents special problems in clinical practice. The traditional diagnostic algorithm in this case involves the exclusion of infections, cancer, and rheumatic diseases. The causes of fever can be severe types of rheumatoid arthritis, systemic vasculitis, and diffuse connective tissue diseases, as well as rare diseases, the difficulty of diagnosis of which is due to low awareness of the disease and the absence of specific clinical, laboratory, and instrumental signs. These also include relapsing polychondritis (RPC) in particular. RPC is a rare systemic inflammatory disease of cartilage tissue, which leads to its structural changes resulting in complete destruction. Cartilages of the acoustic apparatus, nose, trachea, and joints are mainly affected. The severity of cardiovascular injury in RPC has recently been emphasized. This disease is observed with equal frequency in men and women, primarily at the age of 40–60 years, predominantly in white people, but it also occurs in other populations. The etiology of RPC is unknown. There are no pathognomonic laboratory and instrumental tests for the diagnosis of RPC. A unified approach to treating this condition has not been elaborated. The available data on the pathogenesis, various clinical manifestations and treatment options of the disease are analyzed. The authors’ own observations of RPC are depicted.
More than an Artist in the Making: Samuel Beckett’s “Assumption” Revisited
Authors: Fernández José Francisco 
Published: September 2019

Abstract
Samuel Beckett’s first published short story, “Assumption” (1929), is usually described as an apprentice work, “a piece of marginally interesting juvenilia” (Pattie 2000: 52), a beginner’s attempt toward a modernist short story in which the influence of James Joyce is clear. Indeed, it has been claimed that Joyce’s A Portrait of the Artist as a Young Man is the model underlying Beckett’s early foray into creative fiction. The current paper seeks to reassess the established critical appreciation of “Assumption”, that of being a parody of Joyce’s novel by a playful disciple; instead, I will argue that Beckett was in fact questioning the very principles of his master’s art. If Portrait is the epitome of the Künstlerroman, Beckett in his short piece debunked the myth of the young artist by consciously downgrading the aesthetic concerns of his protagonist and by disrupting the revered categories of modernist fiction.This essay is part of the research project FF I 2016-76477-P, funded by the Spanish Ministerio de Ciencia, Innovación y Universidades and by AEI / FEDER. The author would also like to thank CEI Patrimonio (Universidad de Almería) for their support..
John Barth and David Foster Wallace: An Abortive Patricide
Authors: Ziegler Heide 
Published: September 2019

Abstract
David Foster Wallace initially saw himself as a late postmodernist; indeed, he literally wrote a text in the margins of his copy of John Barth’s Lost in the Funhouse. Later on, probably under the influence of Harold Bloom’s The Anxiety of Influence, he wanted to become one of those “strong poets” who need to commit a literary patricide so as to clear imaginative space for themselves. What has been more or less overlooked so far (or perhaps simply taken for granted, given the widespread recognition and influence of Creative Writing Seminars in the U. S.) is that Wallace used the model of teacher and student to create his own relationship between Author and Reader, turning the story into a battleground between them. This essay attempts to show that Wallace’s “homicidal” as well as “fawning” attitude towards Barth actually raises the status of the author he means to succeed.
False Generosity of the State: Parasitic Subjectivity in J. M. Coetzee’s Life and Times of Michael K
Authors: Keramatfar Hossein , Bavakhani Sara 
Published: September 2019

Abstract
This paper holds that J. M. Coetzee’s novel, Life and Times of Michael K, demonstrates how apartheid, in order to preserve its domination over the nonwhite population of South Africa, as with other authoritarian regimes, commonly encouraged dependency. Its various institutions and camps aimed precisely to create a culture of dependence and to fashion subjects utterly dependent on the state. A dependent subject is a powerless, exploitable, and controllable subject; this is the right kind of subject for colonizers. The black majority of South Africa, then, could only have a parasitic existence, completely dependent on their white masters. The novel narrates how dependence is created through the false generosity of the state. As Paulo Freire in Pedagogy of the Oppressed argued, false charity is a state strategy that serves to reproduce the relations of domination. Coetzee’s novel, thus, suggests that to undermine the structure of domination, the oppressed have to reject the culture of dependence and the parasitic subjectivity that arise from the false generosity of the state.
Research on elastic recoil and restoration of vessel pulsatility of Zn-Cu biodegradable coronary stents
Authors: Zhou Chao , Feng Xiangyi , Shi Zhangzhi , Song Caixia , Cui Xiaoshan , Zhang Junwei , Li Ting , Toft Egon Steen , GE Junbo , Wang Luning , Zhang Haijun 
Published: September 2019

AbstractCoronary stents made of zinc (Zn)-0.8 copper (Cu) (in wt%) alloy were developed as biodegradable metal stents (Zn-Cu stents) in this study. The mechanical properties of the Zn-Cu stents and the possible gain effects were characterized by in vitro and in vivo experiments compared with 316L stainless steel stents (316L stents). Young’s modulus of the as-extruded Zn-0.8Cu alloy and properties of the stents, including their intrinsic elastic recoil, stent trackability were evaluated compared with 316L stents. In vivo study was also conducted to evaluate restoration of pulsatility of vessel segment implanted stents. Both Zn-Cu stents and 316L stents have good acute lumen gain. By comparison, the advantages of Zn-Cu stents are as follows: (I) Zn-Cu stents have less intrinsic elastic recoil than 316L stents; (II) stent trackability indicates that Zn-Cu stents have a smaller push force when passing through curved blood vessels, which may cause less mechanical stimulation to blood vessels; (III) in vivo study suggests that Zn-Cu stents implantation better facilitates the recovery of vascular pulsatility.
Modelling a production process using a Sankey diagram and Computerized Relative Allocation of Facilities Technique (CRAFT)
Authors: Rudolf Kampf , Martina Hlatká 
Published: September 2019

Abstract
This paper constitutes a partial output of carried out research and is focused on modelling the production process of car seat manufacturing. Given that manufacturing companies are currently struggling with a shortage of qualified workforce, it is the job of every business to keep their current employees. Companies make efforts to operate the most efficient production processes at very low cost and with labour saving. In order to produce at low cost, the work environment must be designed efficiently. There are many ways to do this. In this paper focused on optimizing production processes, Computerized Relative Allocation of Facilities Technique (CRAFT) and a Sankey diagram will be used.
Synthesis and characterization of Cu doped chromium oxide (Cr2O3) thin films
Authors: Zekaik Ahlam , Benhebal Hadj , Benrabah Bedhiaf 
Published: September 2019

AbstractCu-doped Cr2O3thin films were deposited onto glass substrate by the sol–gel dip-coating (SGDC) process using dopant values of 0, 3, 6, 9 and 12%. The Chromium (III) Nitrate Nonahydrate [Cr(NO3)3·9H2O] was used as a Cr source, whilst for the dopant, the corresponding nitrate (Cu(NO3)2) was used. The crystal structure, as well as the optical and electrical properties were examined. XRD data showed that the films with a high degree of crystallinity were rhombohedral Cr2O3phase. The crystallite size reduces with increase in Cu doping proportion. The AFM results indicate a decrease in the surface roughness of the doped Cr2O3: Cu thin films. The UV-Vis spectra of the Cu doped-Cr2O3films showed high transparency in the visible region. The optical band gap of Cr2O3thin films decreases with increasing in Cu doping rate. The Nyquist plot shows that the equivalent circuit of Cu doped-Cr2O3films is a parallel circuit RpCp. As the concentration of Cu increases, Resistance RPregresses while capacitance Cpincreases.
Developing an Accurate Heat Transfer Simulation Model of Alaska Pollock Surimi Paste by Estimating the Thermal Diffusivities at Various Moisture and Salt Contents
Authors: Park Hyeon W. , Lee Myeong G. , Park Jae W. , Yoon Won B. 
Published: September 2019

Abstract
Alaska pollock (AP) surimi paste was prepared (0–3% salt and 76–84% moisture). The density, specific heat, and thermal conductivity were measured and modelled in temperatures between 25 and 90 °C (R
2 > 0.92). The thermal diffusivity (α) function showed a strong dependence on the moisture content and a unique salt dependence at 84% of the moisture content and applied to the heat transfer simulation of surimi paste. The simulation model coupled with the empirical thermal properties accurately predicted the heat penetration curves during heating with RMSE values ranging from 0.43 to 1.22 °C. The salt dependence on thermal diffusivity was identified and modeled only at 84% moisture content. With a model for 84% moisture content, the RMSE value of 3% salt content decreased from 1.11 °C to 0.56 °C. This study demonstrated that an accurate prediction of the heat transfer of the surimi paste needs to be coupled with the nonlinear thermal diffusivity functions.
A review on the management of asthma in the Avicenna’s Canon of Medicine
Authors: Amini Fatemeh , Jaladat Amir Mohammad , Atarzadeh Fatemeh , Mosavat Seyed Hamdollah , Parvizi Mohammad Mahdi , Zamani Nasrindokht 
Published: September 2019

Abstract

Introduction
In this study, we attempted to identify medicinal plants for treating asthma by investigating Persian Medicine (PM) sources.

Methods
In the present review study, materials concerning asthma were assessed by the (most) reliable source of PM (Canon of Medicine) written by Avicenna. Recommended medicinal plants for treating asthma were extracted from this book. Likewise, the electronic databases were used for investigating the pharmacological properties of offered herbs.

Results
The signs and symptoms of “Rabv” discussed by Avicenna are very similar to the asthma in modern medicine. Avicenna dichotomized asthma causing into pulmonary and non-pulmonary ones, including asthma with the heart, liver, or stomach origin. Overall, 14 medicinal plants were mentioned for the treatment of asthma presented in Canon of Medicine, including celery, juniper, dodder, chamomile, fennel, quince seed, black caraway, lavender, hyssop, squill, anise, absinthe, asafoetida, and common polypody.

Conclusions
PM prescribes medicinal plants for treating asthma, based on each patient’s symptoms and trigger factors.
Antimalarial plants with potential male-factor antifertility properties
Authors: Adewole Kayode Ezekiel , Attah Alfred Francis 
Published: September 2019

Abstract
Malaria, caused mainly by Plasmodium falciparum among other Plasmodium species, is one of the main causes of death from parasitic diseases. Malaria is still a health problem mainly because of the cost of effective antimalarial drugs and the growing parasite resistance to conventional antimalarial drugs, making a great proportion of the people in malaria endemic countries dependent on plants for its treatment. Corollary, a large number of the rural populations consume antimalarial herbal preparations in large or excessive quantities despite the fact that it has been reported that some of them could cause male-factor infertility, a growing global health concern. Few studies have compiled information on the scientifically validated male-factor antifertility effects of these antimalarial plant remedies. The aim of this review therefore is to compile information on commonly used antimalarial plant remedies that have been experimentally validated as having male-factor antifertility effects. Thus, antimalarial plant remedies with experimentally confirmed male-factor antifertility potentials and compounds isolated from them are identified and discussed. The male-factor antifertility effects of these plants include reduction of sperm quality, regulation of reproductive hormone levels and induction of lipid peroxidation. Indiscriminate use of such antimalarial plants is discouraged when male contraception is not desired.
Coupling of deterministically activated quantum emitters in hexagonal boron nitride to plasmonic surface lattice resonances
Authors: Proscia Nicholas V. , Collison Robert J. , Meriles Carlos A. , Menon Vinod M. 
Published: September 2019

Abstract
The cooperative phenomena stemming from the radiation field-mediated coupling between individual quantum emitters are presently attracting broad interest for applications related to on-chip photonic quantum memories and long-range entanglement. Common to these applications is the generation of electro-magnetic modes over macroscopic distances. Much research, however, is still needed before such systems can be deployed in the form of practical devices, starting with the investigation of alternate physical platforms. Quantum emitters in two-dimensional (2D) systems provide an intriguing route because these materials can be adapted to arbitrarily shaped substrates to form hybrid systems wherein emitters are near-field-coupled to suitable optical modes. Here, we report a scalable coupling method allowing color center ensembles in a van der Waals material (hexagonal boron nitride) to couple to a delocalized high-quality plasmonic surface lattice resonance. This type of architecture is promising for photonic applications, especially given the ability of the hexagonal boron nitride emitters to operate as single-photon sources at room temperature.
Principles and techniques of the quantum diamond microscope
Authors: Levine Edlyn V. , Turner Matthew J. , Kehayias Pauli , Hart Connor A. , Langellier Nicholas , Trubko Raisa , Glenn David R. , Fu Roger R. , Walsworth Ronald L. 
Published: September 2019

AbstractWe provide an overview of the experimental techniques, measurement modalities, and diverse applications of the quantum diamond microscope (QDM). The QDM employs a dense layer of fluorescent nitrogen-vacancy (NV) color centers near the surface of a transparent diamond chip on which a sample of interest is placed. NV electronic spins are coherently probed with microwaves and optically initialized and read out to provide spatially resolved maps of local magnetic fields. NV fluorescence is measured simultaneously across the diamond surface, resulting in a wide-field, two-dimensional magnetic field image with adjustable spatial pixel size set by the parameters of the imaging system. NV measurement protocols are tailored for imaging of broadband and narrowband fields, from DC to GHz frequencies. Here we summarize the physical principles common to diverse implementations of the QDM and review example applications of the technology in geoscience, biology, and materials science.
Powerless? Modelling God’s Acting in the World in Eschatological Terms
Authors: Teuchert Lisanne 
Published: September 2019

Summary
This essay deals with the fundamental problem in which the doctrine of providence, that is God’s acting in nature, history and individual life, is still stuck: the dilemma of theism or deism, God’s superiority or powerlessness. I introduce an eschatological perspective to find alternative approaches to power. I name six concrete modes of action, four of them drawn from different authors and theories such as Romano Guardini, Open Theism and Christian Link. Two more are developed out of the latter.
Covenant Relation as Prolegomena to Knowledge of God: An Exegetical Study of John 5
Authors: Shannon Nathan D. 
Published: September 2019

Summary
The classical view of the Creator-creature relation conveys ontological asymmetry by affirming a real creature-Creator relation and a rational Creator-creature relation. But the hermeneutical implications of this view obscure the Creator-creature symmetry of biblical religion. In this article I propose a real covenant relation as a divine initiative establishing a relation within which Creator-creature intercourse is possible, actual, and real. I defend the notion of real covenant relation through a study of John 5, and I develop it theologically with reference to Reformed biblical and covenant theology. A real covenant relation preserves ontological asymmetry, vindicates religious symmetry, and affirms rather than obscures the anthropomorphic tenor of biblical revelation.