bluuebunny/crossref_metadata_2025_split huggingface dataset:
The troublesome guidance towards academic literacy.
Authors: Greek Marit , Jonsmoen Kari Mari 
Published: May 2018

According to research findings, students having graduated from upper secondary school, ought to be sufficiently prepared for meeting the demands of higher education, and for further developing their textual competences within the discipline specific contexts. Nevertheless, according to lecturers and librarians in higher education, students are still in need of guidance in their textual work. The question is what the students need and who are qualified for guiding the students. The overall goal is to promote a meaningful writing process, when assisting the students towards the planned academic learning outcome. The article discusses «Writing courses» as a phenomenon, in light of writing theory and literacy research. According to international research findings, writing in higher education is part of a disciplinary discourse, and disciplinary literacy skills are essential for building textual competences within a specific disciplinary community. Thus the essential factors in guiding students in their writing process, are genre conventions, text organization and argumentation. However, the students also need guidance in searching relevant literature as well as dealing with sources in a correct manner. The article emphasizes the significance of textual knowledge when guiding the students in higher education. However, librarians and lecturers possess different knowledge, and are part of different disciplinary discourses. There is therefore a need for debating what guidance in writing is to be, and how lecturers and librarians can complement each other and together offer constructive and relevant guidance.
Tracking State-Level Health Impact Assessment Legislation from 2012-2016
Authors: Waimberg Joshua , Cloud Lindsay K. , Campbell Andrew T. , Lindberg Ruth , Pollack Keshia M. 
Published: June 2018

Background: To collect and analyze state-level Health Impact Assessment (HIA) legislative activity.
Methods: Two longitudinal datasets examining state-level HIA legislation across the United States between January 1, 2012 and December 31, 2016 were developed using the policy surveillance process. One dataset captures the characteristics of all HIA bills that were introduced and failed, or introduced and were still under consideration, during the time period of the study; the second dataset captures the characteristics of all HIA laws that were enacted or amended, including statutes and regulations.
Results: Forty-three HIA bills were introduced that require, encourage, or incentivize the use of an HIA, and three of these bills were enacted or amended into law, between January 1, 2012 and December 31, 2016.
Conclusions: Additional research is necessary to understand the factors that drive success or failure of HIA legislation, and the impacts of such legislation when implemented on decision-making, health determinants and outcomes, and health equity.
Policy Implications: Although legislation can encourage further use of HIAs, they need to provide sufficient clarity, guidance, and resources to effectively foster use of HIAs.
Thyroid dysfunction in patients with diabetes mellitus at Puducherry, India: a retrospective study
Authors: Hussain K. Shaik Anwar 
Published: June 2018

Background: There is a complex interrelationship in the co-existence of thyroid dysfunction among diabetic patients and may be related to the development of cardiovascular diseases and other complications of long term metabolic derangements. The prevalence of thyroid dysfunction varies from 10 to 24% among diabetic patients. The objective of the present study was to determine the prevalence of thyroid dysfunction among the patients with diabetes mellitus in a tertiary care hospital at Puducherry, India.Methods: This retrospective study was conducted during June 2018 analysing the records of diabetes patients attending to the diabetes OPD, Department of General Medicine in the past one year and their association with thyroid dysfunction was studied.Results: Among the study participants (n=200), 14.5% (n=29) were Type I diabetics and 85.5% (n=171) were type II Diabetes patients. The prevalence of Thyroid Dysfunction (TD) among the study participants was 28.5% (n=57). The proportion of TD was higher among type 1 DM compared to type 2 (p<0.001). The prevalence of subclinical hypothyroidism was more (n=7, 24.1%) among type 1DM compared to type II DM patients (p=0.05).Conclusions: There was a higher prevalence of TD among the diabetics. TD was more frequent among type 1 DM compared to Type 2 DM patients and the most frequent TD associated with diabetes was subclinical hypothyroidism.
On Generalized Pseudo-Projectively Recurrent Manifolds
Authors: Singh J. P. , Lalmalsawma C. 
Published: June 2018

<p>The object of the present paper is to study generalized pseudo-projectively recurrent manifolds. Some geometric properties of generalized pseudo-projectively recurrent manifolds have been studied under certain curvature conditions. Finally the existence of generalized pseudo-projectively recurrent manifold is shown by examples.</p>
Dietary supplement use among patients with chronic kidney disease
Authors: Jakimowicz-Tylicka Marzena , Chmielewski Michal , Kuźmiuk-Glembin Izabella , Skonieczny Piotr , Dijakiewicz Grażyna , Zdrojewska Grażyna , Rutkowski Bolesław , Tylicki Leszek , Dębska-Ślizień Alicja 
Published: May 2018

Background: Dietary supplements (DS) are available over the counter, and no detailed data on their use is available. Patients with impaired renal function are at risk of toxicity associated with DS. The aim of the study was to evaluate the prevalence and characteristics of DS use in patients with chronic kidney disease (CKD).Material and methods: A cross-sectional controlled survey study in 180 CKD patients (stage 1-5, dialysis, kidney transplant), 60 patients without CKD served as controls.Results: Self-medication with DS did not differ between subjects with and without CKD. In the CKD group, 20% admitted to use DS regularly, 22% did not take them at all. In the controls, this was 17% and 13%, respectively (NS). The DS use was higher among women as compared to men (89% vs. 70%; p<0.005), and people living in cities in comparison to patients living in villages (81% vs. 63%; p<0.05). DS agents most commonly used were: vitamins, mineral substances and herbs. Major indications for self-medication with DS included: musculoskeletal issues, general health improvement and prevention of urinary tract infections. Subgroup analyses revealed that dialysis patients were characterized by a significantly higher DS use in comparison to CKD stage 1-5 subjects and renal transplant recipients. The decision on introducing DS was made by the physician in 54% of cases; by a pharmacist in 9% of cases, and by the patients themselves in 37%. Only 21% of patients with CKD, and 27% of subjects without CKD declared knowledge of any possible side-effects associated with DS (NS).Conclusions: The use of DS among patients with CKD is similar to patients without CKD, and is most prevalent among patients on dialysis. Vitamins and minerals are the most commonly used DS. The knowledge on the side-effects of DS is very limited.
Treatment of Non-erosive Effect of Clinical Study of Gastroesophageal Reflux Disease
Authors: Liu Qian 
Published: May 2018

<p class="18">Abstract: Objective: To observe the clinical effect of “Chaihu Shugan Powder Zuojin Pill” in the treatment of non-erosive gastroesophageal reflux disease. Methods: Sixty patients with non-erosive gastroesophageal reflux disease were randomly divided into treatment group and control group (30 cases in each group). The patients were treated with “Zaohu Shugan Powder” and “Zangjin Pills” and omeprazole respectively. For 8 weeks, the clinical efficacy and changes in clinical symptoms were observed. Results: The total effective rate was 93.3% in the treatment group and 80.0% in the control group. There was significant difference between the two groups before and after treatment (P &lt;0.05). Conclusion: “Chaihu Shugan Powder Zuojin Pill” can effectively improve the clinical symptoms of non-erosive gastroesophageal reflux disease.</p>
IMPLEMENTATION OF SYARI'AH ECONOMIC PRINCIPLES ON THE MANAGEMENT OF SYARI'AH MUTUAL FUND IN INDONESIA
Authors: Rodliyah Nunung , Ramasari Risti Dwi 
Published: June 2018

Syari’ah Financial Institution is one of the institutions of Islamic doctrine that is currently mushrooming in the midst of modern Indonesian society. Along with the growth of syari'ah financial institutions, MUI issued that interest is usury which is unlawful. The entry of syari'ah financial institutions in Indonesia made a new breakthrough in the syari'ah capital market. One of the products of syari'ah capital market is Syari'ah Mutual Fund. Syari'ah mutual funds are defined as mutual funds as referred to in the Capital Market Law and its implementing regulations whose management does not conflict with the principles of syari'ah in the capital market. The problem of this research is how is the interpretation of the regulation of syari'ah economic principle in Indonesia and how is the management of Syari'ah Mutual Funds based on syari'ah economic principle in Indonesia. This research is normative research with descriptive research type. The approach used is normative juridical. The data collection was done by literature study and document study. The data used are secondary data consisting of primary legal materials, secondary legal materials, and tertiary legal materials. The collected data is then analyzed qualitatively. The findings of the research show that there are 3 (three) principles of syari'ah economy namely the principles of Tauhid, Justice, and Benefits. The regulation of syari'ah economic principles in Indonesia is regulated in the DSN-MUI and compilation of Islamic law. Basically syari'ah economic principles are in the field of Bank financial institutions and Non-Bank financial institutions. The arrangement of syari'ah economic principles, as well as regulated in law but also governed by Syar'i Law and Fiqh law through Ijtihad, by the method of Mashlahah Mursalah. Implementation of investments in Syari'ah Mutual Fund transaction mechanism in investing through Syari’ah Mutual Funds should pay attention to things that are not against the Islamic Syari'ah. Implementation of the transaction contract should not be contrary to the Islamic Syari'ah, whether prohibited because (1) Forbidden in addition to the substance, which contains tadlis, ihtikar, ba'i najasy, garar, and usury, as well (2) Because unauthorized, i.e. the order and conditions are not met, there ta'alluq, and there are two contracts in one transaction simultaneously. The idea of syari’ah economic principles recommends to the Syari’ah Banking Supervisory Board to make further regulation in the development of investing through Syari’ah Mutual Funds in Indonesia.
Performance of modified twin pit toilet in Mulbagal town, Karnataka, India
Authors: Rao Sudhakar M. , Arkenadan Lydia , Mogili Nitish V. 
Published: May 2018

Abstract
Transformation of ammonium to nitrate upon sewage discharge to sub-surface environment exposes about 65 million households in rural and urban India to risks of drinking nitrate contaminated groundwater. Building on earlier research, a twin pit is modified in Mulbagal town, Karnataka, to remove nitrate in pit toilet sewage and is functional for nearly one year. The first pit serves as an anaerobic chamber, while the second pit facilitates aerobic reactions in the upper half and is equipped with a bio-barrier in its lower half. Quality of treated sewage is monitored by soil water samplers installed adjacent to the pit. After anaerobic digestion in pit 1, sewage flows into the aerobic chamber (upper half of pit 2), where COD/N ratio of 1.49 to 1.73 facilitates aerobic conversion of ammonium to nitrite and nitrate ions. Annamox reactions in a bio-barrier chamber (lower half of pit 2) reduce ammonium and nitrite concentrations, while denitrification reactions in the bio-barrier remove nitrite and nitrate from pit toilet sewage. Besides nitrate, the modified twin pit reduces COD (chemical oxygen demand), ammonium, and thermotolerant coliform levels in the discharged sewage.
Farmers' adaptation choices to climate change: a case study of wheat growers in Western Iran
Authors: Azadi Yousof , Yazdanpanah Masoud , Forouzani Masoumeh , Mahmoudi Hossein 
Published: June 2018

AbstractClimate change is expected to disproportionately affect farmers by further exacerbating the risks that they face. These risks have a huge negative impact on their livelihood. However, mounting evidence has revealed that farmers can effectively manage this negative impact by adapting their farming practices to climate change. The objectives of this study were to evaluate the farmers' ongoing adaptation measures, and to identify factors that influence their choice of adaptation methods in wheat production in the Kermanshah district in Western Iran. A sample of 350 farmers living in this region was selected through a multi-stage stratified and random sampling method. Principal component analysis revealed that three components play a role in the farmers' decisions on adaptation methods, namely, farm production practices, farm financial management, and government programs and insurance. The relative influence of the factors listed under each of the three components was assessed using a multiple linear regression analysis. Our analysis showed that these factors accounted for 50%, 25%, and 40% of the adaptation responses analyzed, respectively. In sum, our findings yield recommendations for agriculture extension and risk communication strategies that could promote adaptation behavior among Iranian farmers.
Humic acid degradation by fenton-like process using Fe2+ and Mn4+
Authors: Sarmento Antover Panazzolo , Borges Alisson Carraro , de Matos Antonio Teixeira , Romualdo Lincoln Lucílio 
Published: May 2018

Abstract
This study investigates the Humic Acid (HA) degradation in aqueous solution by a Fenton-Like process using Fe2+ and Mn4+ as a catalyst. The effect of the independent factors: pH, [H2O2], [Fe2+], [Mn4+] and t (reaction time) at the efficiency of HA degradation were evaluated, aiming at obtaining the optimum conditions. The statistic arrangement adopted was the Central Composite Design, and the response variable was the HA relative concentration after the treatments. The inferences were made using variance analysis, the Pareto chart, the response surface method and the desirability function. The variables which were more significant at the HA degradation were: [Fe2+] (linear and square effects), pH (square effect) and the interactions between [Fe2+] vs [H2O2] and [Fe2+] vs t. The addition of Mn4+ did not provide a significant improvement to the efficiency of HA degradation. Nevertheless, it was observed that the conventional Fenton process proved to be an efficient alternative for the HA degradation. The optimal and most economical condition is pH 5, [H2O2] of 6.17 mmol L−1, [Fe2+] of 0.54 mmol L−1, reaction time of 120 min and no added Mn4+.
Enhanced biotreatment of acid mine drainage in the presence of zero-valent iron and zero-valent copper
Authors: Hu Xiaobing , Lin Biaosheng , Gao Fengqing 
Published: June 2018

Abstract
Batch laboratorial experiments were conducted to evaluate the potential of Fe0, Cu0 and sulfate-reducing bacteria (SRB) for reduction and removal of sulfate and heavy metals from synthetic acid mine drainage. The variation in solution pH indicates that the Fe0/Cu0 bimetallic system provided favorable conditions for SRB growth and sulfate reduction. When the SO42− concentration of wastewater was 3,000 mg/L, the SO42− removal efficiency was 51.6% for the SRB system, 76.3% for the Fe + SRB system, and 92.0% for the Fe/Cu + SRB system. Moreover, Pb2+, Cu2+ and Zn2+ ions were completely removed. The results demonstrate that the Fe/Cu + SRB system had apparent advantages over the SRB system, especially at low pH. This study demonstrates that an Fe/Cu + SRB system could be a promising technology for treating wastewater containing high concentrations of sulfate and heavy metals.
Graphene oxide edge grafting of polyaniline nanocomposite: an efficient adsorbent for methylene blue and methyl orange
Authors: Wang Hefang , Duan Mengmeng , Guo Yong , Wang Cunyue , Shi Zetao , Liu Jidong , Lv Jianhua 
Published: June 2018

Abstract
Polyaniline (PANI) chains were grafted at the edge of graphene oxide (GO) sheets by in-situ chemical oxidation polymerization. The obtained GO-PANI composite was used for the adsorption of cationic methylene blue (MB) and anionic methyl orange (MO) dyes from aqueous solutions. The structure of the GO-PANI composite was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electronic micrograph (SEM), X-ray photoelectron spectroscopy (XPS) and zeta potentials. GO-PANI exhibited a high adsorption capacity for MB (962 mg/g) and MO (885 mg/g) compared with other reported absorbents, which was due to adsorption through strong π-π stacking and anion–cation interactions. The nanocomposite could be recycled five times without significant loss in removal abilities for MB (87.8%) and MO (75.0%), respectively. GO-PANI composite is a promising adsorbent for the adsorption of anionic and cationic dyes from aqueous solutions.
Influence of Oxidative Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate Dehydrogenase
Authors: Muronetz Vladimir I. , Melnikova Aleksandra K. , Saso Luciano , Schmalhausen Elena V. 
Published: May 2018

Background:Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) is a unique enzyme that, besides its main function in glycolysis (catalysis of glyceraldehyde-3-phosphate oxidation), possesses a number of non-glycolytic activities. The present review summarizes information on the role of oxidative stress in the regulation of the enzymatic activity as well as non-glycolytic functions of GAPDH.Methods:Based on the analysis of literature data and the results obtained in our research group, mechanisms of the regulation of GAPDH functions through the oxidation of the sulfhydryl groups in the active site of the enzyme have been suggested.Results:Mechanism of GAPDH oxidation includes consecutive oxidation of the catalytic Cysteine (Cys150) into sulfenic, sulfinic, and sulfonic acid derivatives, resulting in the complete inactivation of the enzyme. The cysteine sulfenic acid reacts with reduced glutathione (GSH) to form a mixed disulfide (S-glutathionylated GAPDH) that further reacts with Cys154 yielding the disulfide bond in the active site of the enzyme. In contrast to the sulfinic and sulfonic acids, the mixed disulfide and the intramolecular disulfide bond are reversible oxidation products that can be reduced in the presence of GSH or thioredoxin.Conclusion:Oxidation of sulfhydryl groups in the active site of GAPDH is unavoidable due to the enhanced reactivity of Cys150. The irreversible oxidation of Cys150 is prevented by Sglutathionylation and disulfide bonding with Cys154. The oxidation/reduction of the sulfhydryl groups in the active site of GAPDH can be used for regulation of glycolysis and numerous side activities of this enzyme including the induction of apoptosis.
Biological Consequences of Dysfunctional HDL
Authors: Pirillo Angela , Catapano Alberico Luigi , Norata Giuseppe Danilo 
Published: May 2018

:Epidemiological studies have suggested an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and the risk of cardiovascular disease. HDLs promote reverse cholesterol transport (RCT) and possess several putative atheroprotective functions, associated to the anti-inflammatory, anti-thrombotic and anti-oxidant properties as well as to the ability to support endothelial physiology.:The assumption that increasing HDL-C levels would be beneficial on cardiovascular disease (CVD), however, has been questioned as, in most clinical trials, HDL-C-raising therapies did not result in improved cardiovascular outcomes. These findings, together with the observations from Mendelian randomization studies showing that polymorphisms mainly or solely associated with increased HDL-C levels did not decrease the risk of myocardial infarction, shift the focus from HDL-C levels toward HDL functional properties. Indeed, HDL from atherosclerotic patients not only exhibit impaired atheroprotective functions but also acquire pro-atherogenic properties and are referred to as “dysfunctional” HDL; this occurs even in the presence of normal or elevated HDL-C levels. Pharmacological approaches aimed at restoring HDL functions may therefore impact more significantly on CVD outcome than drugs used so far to increase HDL-C levels. The aim of this review is to discuss the pathological conditions leading to the formation of dysfunctional HDL and their role in atherosclerosis and beyond.
The Therapeutic Impact of New Migraine Discoveries
Authors: Vécsei László , Lukács Melinda , Tajti János , Fülöp Ferenc , Toldi József , Edvinsson Lars 
Published: May 2018

Background:
Migraine is one of the most disabling neurological conditions and
associated with high socio-economic costs. Though certain aspects of the pathomechanism of
migraine are still incompletely understood, the leading hypothesis implicates the role of the
activation of the trigeminovascular system. Triptans are considered to be the current gold
standard therapy for migraine attacks; however, their use in clinical practice is limited. Prophylactic
treatment includes non-specific approaches for migraine prevention. All these support
the need for future studies in order to develop innovative anti-migraine drugs.

Objective:
The present study is a review of the current literature regarding new therapeutic
lines in migraine research.

Methods:
A systematic literature search in the database of PUBMED was conducted concerning
therapeutic strategies in a migraine published until July 2017.

Results:
Ongoing clinical trials with 5-HT1F receptor agonists and glutamate receptor antagonists
offer promising new aspects for acute migraine treatment. Monoclonal antibodies against
CGRP and the CGRP receptor are revolutionary in preventive treatment; however, further
long-term studies are needed to test their tolerability. Preclinical studies show positive results
with PACAP- and kynurenic acid-related treatments. Other promising therapeutic strategies
(such as those targeting TRPV1, substance P, NOS, or orexin) have failed to show efficacy in
clinical trials.

Conclusion:
Due to their side-effects, current therapeutic approaches are not suitable for all
migraine patients. Especially frequent episodic and chronic migraine represents a therapeutic
challenge for researchers. Clinical and preclinical studies are needed to untangle the pathophysiology
of migraine in order to develop new and migraine-specific therapies.