bluuebunny/crossref_metadata_2025_split huggingface dataset:
Project ECHO-Geriatrics: Training Future Primary Care Providers to Meet the Needs of Older Adults
Authors: Bennett Katherine A. , Ong Thuan , Verrall Aimee M. , Vitiello Michael V. , Marcum Zachary A. , Phelan Elizabeth A. 
Published: April 2018

ABSTRACTBackground Geriatrics training is essential for future primary care providers. The Extension for Community Healthcare Outcomes (ECHO) model improves access to specialty care via case-based videoconferencing, but Project ECHO has not previously been designed to target residents.Objective We designed Project ECHO-Geriatrics to deliver geriatrics education to primary care trainees using the ECHO model and evaluated self-rated geriatrics competency of trainees from the University of Washington Family Medicine Residency Network programs who participated between January 2016 and March 2017.Methods We assessed outcomes of Project ECHO-Geriatrics through anonymous surveys. Participants rated didactics, case discussions, and geriatrics-specific knowledge before and after sessions on a 5-point scale (1, low, to 5, high). Participants were asked whether they planned to do anything differently in their practice and, if yes, to describe this change.Results Fifteen sessions were held with 204 unique participants from 12 sites, with an average of 28 (range, 13–41) participants per session. From the 9 of 29 (31%) Family Medicine Residency Network programs that enrolled, 63% percent (116 of 184) of eligible residents attended. Sessions were highly rated (89% of responses were 4 or 5). Self-reported geriatrics-specific knowledge increased significantly (before 3.3 [SD = 0.89] versus after 4.0 [SD = 0.60], P &lt; .001). Sixty-five percent (118 of 181) of participants reported plans to change their practice.Conclusions Project ECHO-Geriatrics is an innovative, feasible way to train the future primary care workforce in geriatrics and grow the capacity to provide high-quality care to older adults.
Gradient flux measurements of sea–air DMS transfer during the Surface Ocean Aerosol Production (SOAP) experiment
Authors: Smith Murray J. , Walker Carolyn F. , Bell Thomas G. , Harvey Mike J. , Saltzman Eric S. , Law Cliff S. 
Published: April 2018

Abstract. Direct measurements of marine dimethylsulfide (DMS) fluxes are sparse, particularly in the
Southern Ocean. The Surface Ocean Aerosol Production (SOAP) voyage in
February–March 2012 examined the distribution and flux of DMS in a biologically active frontal system in the southwest Pacific Ocean.
Three distinct phytoplankton blooms were studied with oceanic DMS
concentrations as high as 25 nmol L−1. Measurements of DMS fluxes were
made using two independent methods: the eddy covariance (EC) technique using
atmospheric pressure chemical ionization–mass spectrometry (API-CIMS) and
the gradient flux (GF) technique from an autonomous catamaran platform.
Catamaran flux measurements are relatively unaffected by airflow distortion
and are made close to the water surface, where gas gradients are largest. Flux
measurements were complemented by near-surface hydrographic measurements to
elucidate physical factors influencing DMS emission. Individual DMS fluxes
derived by EC showed significant scatter and, at times, consistent departures
from the Coupled Ocean–Atmosphere Response Experiment gas transfer algorithm (COAREG). A direct comparison between the
two flux methods was carried out to separate instrumental effects from
environmental effects and showed good agreement with a regression slope of
0.96 (r2= 0.89). A period of abnormal downward atmospheric heat
flux enhanced near-surface ocean stratification and reduced turbulent
exchange, during which GF and EC transfer velocities showed good agreement
but modelled COAREG values were significantly higher. The transfer velocity
derived from near-surface ocean turbulence measurements on a spar buoy
compared well with the COAREG model in general but showed less variation.
This first direct comparison between EC and GF fluxes of DMS provides
confidence in compilation of flux estimates from both techniques, as well as in
the stable periods when the observations are not well predicted by the COAREG
model.
Tomographic retrievals of ozone with the OMPS Limb Profiler: algorithm description and preliminary results
Authors: Zawada Daniel J. , Rieger Landon A. , Bourassa Adam E. , Degenstein Douglas A. 
Published: April 2018

Abstract. Measurements of limb-scattered sunlight from the Ozone Mapping and Profiler Suite Limb Profiler (OMPS-LP) can be used to
obtain vertical profiles of ozone in the stratosphere. In this paper we describe a two-dimensional, or tomographic,
retrieval algorithm for OMPS-LP where variations are retrieved simultaneously in altitude and the along-orbital-track
dimension. The algorithm has been applied to measurements from the center slit for the full OMPS-LP mission to create the
publicly available University of Saskatchewan (USask) OMPS-LP 2D v1.0.2 dataset. Tropical ozone anomalies are compared with measurements from the
Microwave Limb Sounder (MLS), where differences are less than 5 % of the mean ozone value for the majority of the
stratosphere. Examples of near-coincident measurements with MLS are also shown, and agreement at the 5 % level is
observed for the majority of the stratosphere. Both simulated retrievals and coincident comparisons with MLS are shown at
the edge of the polar vortex, comparing the results to a traditional one-dimensional retrieval. The one-dimensional
retrieval is shown to consistently overestimate the amount of ozone in areas of large horizontal gradients relative to
both MLS and the two-dimensional retrieval.
Are post-dispersed seeds of &lt;i&gt;Eucalyptus globulus&lt;/i&gt; predated in the introduced range? Evidence from an experiment in Portugal
Authors: Deus Ernesto , Silva Joaquim S. , Marchante Hélia , Marchante Elizabete , Félix Catarina 
Published: April 2018

Abstract. Plantations of Eucalyptus globulus Labill. have been expanding rapidly worldwide. The species is considered invasive in several regions. While in the native range, post-dispersal seed predation is known to severely limit eucalypt recruitment, there is no experimental evidence of seed predation in the introduced range. We hypothesised that E. globulus seeds largely escape predation in Portugal, which may explain its prolific recruitment in some locations. We tested this hypothesis in central Portugal by exposing E. globulus seeds to the local fauna. For comparison purposes, we also used seeds from locally common species: Acacia dealbata Link (alien, larger, elaiosome-bearing seeds) and Cistus salviifolius L. (native, similarly sized seeds). We installed 30 feeding stations across three study sites, each one dominated by one study species. Each feeding station featured four feeders with different animal-access treatments: invertebrates; vertebrates; full access; no access (control). We placed five seeds of each plant species every day in each feeder and registered the number of seeds missing, eaten and elaiosome detached over 9 summer days. Eucalyptus globulus seeds were highly attractive to fauna in the three sites. Nearly half of E. globulus seeds were predated or removed, thus contradicting our hypothesis. Surprisingly, E. globulus and A. dealbata seeds were used by animals in similar proportions and C. salviifolius seeds were the least preferred. Vertebrates were the predominant seed predators and preferred the alien seeds. Invertebrates used all seed species in similar proportions. We found spatial variation regarding the predominant type of seed predators and the levels of seed predation according to the following patterns: predominance of vertebrates; predominance of invertebrates; negligible seed predator activity. Locations with negligible seed predation were abundant and scattered across the study area. Such spatial variation may help to explain the heterogeneous recruitment patterns of E. globulus seedlings found in previous studies.
Case Report: Combining Dalfampridine with Multicomponent Exercise and Gait Training in a Person with Multiple Sclerosis
Authors: Plummer Prudence , Bohling Corinne J. , Nickles L. Ellese , Williams Alexis A. , Thomas Amy , Markovic-Plese Silva , Giesser Barbara 
Published: April 2018

Abstract

Background:
Dalfampridine extended release (D-ER) improves gait speed in some people with multiple sclerosis (MS), but many patients who take D-ER demonstrate only small improvements of questionable clinical significance. Physical therapy (PT) may augment the treatment effects of D-ER on the nervous system and improve clinical outcomes. This case report describes the successful use of D-ER combined with multicomponent PT in a patient who did not have a clinically important change in gait speed with D-ER alone.

Methods:
A 59-year-old woman with a 6-year history of relapsing-remitting MS was prescribed D-ER by her neurologist. After 3 weeks of D-ER therapy (10 mg twice daily), she demonstrated only a 7.1% improvement in the Timed 25-Foot Walk test. She then commenced PT consisting of two 40-minute sessions per week for 6 weeks while continuing D-ER therapy. Training focused on gait, balance, coordination, functional strengthening, and dual-task performance.

Results:
After 6 weeks of D-ER + PT, she had a further 14.6% improvement in Timed 25-Foot Walk gait speed, for a total improvement of 20.7%, which elevated her above the clinically meaningful threshold of 20%. Similar patterns of improvement were also observed for self-selected gait speed in single- and dual-task conditions. Improvements in fast and dual-task gait speed were retained 3 weeks later.

Conclusions:
For this patient, combining PT with D-ER therapy improved gait speed more than the use of D-ER alone. Further investigation of D-ER + PT or PT as an alternative to D-ER in patients with submeaningful medication response is warranted.
Avaliação de Riscos Aplicada à Conservação e Restauração do Patrimônio Industrial Móvel: O Rolo Compactador da Escola de Belas Artes, Universidade Federal de Minas Gerais – Brasil
Authors: Silva Ronaldo 
Published: April 2018

Este artigo apresenta uma proposta de avaliação de riscos para a conservação de patrimônio industrial móvel segundo o modelo de gestão de riscos aplicado à conservação preventiva. O objeto de estudo consiste em um rolo compactador rodoviário a vapor alemão, da marca Schwartzkopff, que foi produzido em 1920 e utilizado durante as décadas 1940/1950 nas obras de implantação do Campus Pampulha da Universidade Federal de Minas Gerais (UFMG) em Belo Horizonte, Minas Gerais, Brasil. A metodologia de trabalho se baseia nos métodos do Instituto Canadense de Conservação (IIC) e do Instituto de Património Cul tu ral Espanhol (IPCE), com foco nos modelos de identificação de agentes de deterioração, de Michalski e de avaliação de riscos segundo o Método ABC (Michalski e Pedersoli Jr.). Busca-se assim propor reflexões acerca da preservação de elementos industriais como objetos patrimoniais não somente históricos, mas culturais e incluir a ciência e a tecnologia como fatores de representatividade e identidade de indivíduos, grupos e da sociedade.
<b>Hacia un diseño de investigación académica en danza performance tecnológica</b><br />
Authors: Ceriani Alejandra 
Published: April 2018

<p class="p1">Resumen</p><p class="p2">La investigación en Arte; y más específicamente, la investigación en Danza performances y Tecnologías de la Información y la Comunicación (TIC) -desde la academia<span class="Apple-converted-space"> </span>local-; es un asunto pendiente. Sus contenidos epistemológicos son aún discutibles, proviniendo durante los últimos años, tanto de las propias prácticas hibridas entre informáticos y artes escénicas (sobre todo referido a la producción de obra) como de políticas y estrategias educativas. Esto lo transforma en un argumento heterogéneo, lo que no siempre contribuye a la claridad del debate.</p><p class="p2">Lo esencial de la cuestión es si existe un fenómeno como la investigación transdisciplinar en danza performances y tecnología; según el cual el proceso de discrepancias metodológicas y materiales -entre lo corporal y lo puramente informático- es en sí mismo una parte primordial del resultado de dicha investigación. Y no, como ocurre generalmente, sea “la obra” el resultado “artístico” esperado.<span class="Apple-converted-space"> </span></p><p class="p3"><span class="s1">Palavras clave:<span class="Apple-converted-space"> </span></span>Corpo. Dança performance tecnológica. Investigação acadêmica. Investigação em arte. Metodologias.</p><p class="p3"> </p><p class="p3">PARA UM PROJETO DE INVESTIGAÇÃO ACADÊMICA NA DANÇA PERFORMANCE TECNOLÓGICA</p><p class="p1"><em>Resumo</em></p><p class="p2"><span class="s2"><em>Pesquisa em Arte, e mais especificamente, a pesquisa em performances de danç</em></span><em>a e tecnologias de informação e comunicação (TIC) - da academia local, é uma questão pendente. Os seus conteúdos epistemológicos que surgiram nos últimos anos, ainda são discutíveis tanto das práticas híbridas entre ciência da computação e as artes cênicas (principalmente referentes à produção de trabalho), quanto das políticas e estratégias educacionais. Isso o transforma em um argumento heterogêneo que nem sempre contribui para a clareza do debate.</em></p><p class="p2"><em>A essência da questão é saber se existe um fenômeno como a pesquisa transdisciplinar em performances de dança e tecnologia segundo a qual o processo de discrepâncias metodológicas e materiais - entre o corpóreo e o puramente informatizado - é, por si só, uma parte primordial do resultado da referida investigação, e não, como costuma acontecer, o resultado “artístico” é “o trabalho” esperado.</em></p><p class="p5"><span class="s1"><em>Palavras-chave:<span class="Apple-converted-space"> </span></em></span><em>Corpo. Dança desempenho tecnológico. Investigação académica. Investigação em arte. Metodologias.</em></p>
<b>Memória visual do I Fórum Negro das Artes Cênicas</b><br />[Fabrícia Dias]
Authors: Dias Fabrícia 
Published: April 2018

<p>Realizado em fevereiro de 2017, o I Fórum Negro das Artes Cênicas (FNAC) fomentou discussões<br />e iniciativas no âmbito do ensino das artes cênicas, sobretudo no contexto de articulação da<br />Escola de Teatro e do Programa de Pós-graduação da Universidade Federal da Bahia (UFBA).<br />Desenvolveu atividades dedicadas à formação, promovendo mesas de discussão, conferências,<br />atividades culturais e debates importantes a partir de ateliês temáticos – os ateliês foram espaços<br />de diálogo em que se propusessem sugestivas de inserção de temáticas negras (estética, poética,<br />ensino) no currículo acadêmico e na práxis docente. Esta breve curadoria fotográfica, tecida<br />durante a realização do FNAC por fotógrafos colaboradores da cidade de Salvador, homenageia<br />e busca inscrever na memória esse momento marcante, no qual professores, estudantes, arteeducadores, artistas e coletivos engajados com as pautas negras no âmbito acadêmico e cultural se debruçaram a refletir e propor ações a serem implantadas no ensino superior, promovendo a visibilidade e representatividade de negros e negras pesquisadores e fazedores das artes cênicas, nos âmbitos regional, nacional e internacional.</p>
American College of Rheumatology Provisional Criteria for Global Flares in Childhood‐Onset Systemic Lupus Erythematosus
Authors: Brunner Hermine I. , Holland Michael , Beresford Michael W. , Ardoin Stacy P. , Appenzeller Simone , Silva Clovis A. , Flores Francisco , Goilav Beatrice , Wenderfer Scott E. , Levy Deborah M. , Ravelli Angelo , Khunchandani Raju , Avcin Tadej , Klein‐Gitelman Marisa S. , Feldman Brian M. , Ruperto Nicolino , Ying Jun ,   the PRCSG and PRINTO Investigators
Published: April 2018

ObjectiveTo validate the preliminary criteria of global flare for childhood‐onset SLE (cSLE).MethodsPediatricians experienced in cSLE care (n = 268) rated unique patient profiles; results of standard cSLE laboratory testing and information about the cSLE flare descriptors were presented as follows: global assessment of patient well‐being, physician global assessment of disease activity (MD‐global), Disease Activity Index score, protein/creatinine ratio (PCR), and erythrocyte sedimentation rate (ESR). Using rater interpretation of the course of cSLE (baseline versus followup as the gold standard), performance (sensitivity, specificity, area under the receiver operating characteristic curve [AUC]) of the preliminary flare criteria was tested. An international consensus conference was held to rank the preliminary flare criteria as per the American College of Rheumatology recommendations and delineate threshold scores for minor, moderate, and major flares.ResultsThe accuracy of the 2 highest‐ranked candidate criteria that consider absolute changes (∆) of the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) or British Isles Lupus Assessment Group (BILAG) (numeric scoring: A = 12, B = 8, C = 1, and D/E = 0), MD‐global, PCR, and ESR were confirmed (both AUC >0.93). For the SLEDAI‐based criteria (0.5 × ∆SLEDAI + 0.45 × ∆PCR + 0.5 × ∆MD‐global + 0.02 × ∆ESR) flare scores ≥6.4/3.0/0.6 constituted major/moderate/minor flares, respectively. For the BILAG‐based algorithm (0.4 × ∆BILAG + 0.65 × ∆PCR + 0.5 × ∆MD‐global + 0.02 × ∆ESR) flare scores ≥7.4/3.7/2.2 delineated major/moderator/minor flares, respectively. These threshold values (SLEDAI, BILAG) were all >82% sensitive and specific for capturing flare severity.ConclusionProvisional criteria for global flares in cSLE are available to identify patients who experienced a flare. These criteria also allow for discrimination of the severity of cSLE exacerbations.
A Novel Method to Combine Assessment of Benefit and Harm: Outcome Measures in Rheumatology 3×3 Methodology Applied to Two Active Comparator Trials
Authors: Boers Maarten , Singh Jasvinder A. , Cofield Stacey S. , Bridges S. Louis , Moreland Larry W. , O'Dell James R. , Wu Hongsheng , Leatherman Sarah , Curtis Jeffrey R. 
Published: April 2018

ObjectiveThe Outcome Measures in Rheumatology (OMERACT) 3×3 method analyzes the occurrence of benefit and harm simultaneously at the individual patient level. We applied this method to 2 recent rheumatoid arthritis (RA) trial data sets.MethodsThe Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) and the Rheumatoid Arthritis Comparison of Active Therapies (RACAT) randomized trial outcomes for safety were defined according to OMERACT as having no adverse events (AEs), non‐serious AEs, and serious AEs. Treatment efficacy was defined as good, moderate, or no response. A good treatment response without any AEs was labeled an unqualified success, and no treatment response but at least 1 AE was considered an unmitigated failure. The association between benefit and harm was assessed by chi‐square or exact tests, as appropriate.ResultsIn TEAR, 612 of 755 patients had response data at 48 weeks: 14% of patients experienced unqualified success and 9% had unmitigated failure, with no difference between the treatment arms. Treatment response and AE rates were not correlated. In RACAT, 309 of 353 patients had response data at 48 weeks: 6% of patients experienced unqualified success and 11% had unmitigated failure, with no differences between the treatment arms. Response and AE rates were negatively correlated. The frequency of AEs and serious AEs increased as response decreased (P = 0.008).ConclusionWe found some evidence that clinical response may be reduced by the co‐occurrence of AEs.
Structural and molecular study of the supraspinatus muscle of modern humans (Homo sapiens) and common chimpanzees (Pan troglodytes)
Authors: Potau J. M. , Casado A. , de Diego M. , Ciurana N. , Arias‐Martorell J. , Bello‐Hellegouarch G. , Barbosa M. , de Paz F. J. , Pastor J. F. , Pérez‐Pérez A. 
Published: April 2018

AbstractObjectivesTo analyze the muscle architecture and the expression pattern of the myosin heavy chain (MyHC) isoforms in the supraspinatus of Pan troglodytes and Homo sapiens in order to identify differences related to their different types of locomotion.Materials and methodsWe have analyzed nine supraspinatus muscles of Pan troglodytes and ten of Homo sapiens. For each sample, we have recorded the muscle fascicle length (MFL), the pennation angle, and the physiological cross‐sectional area (PCSA). In the same samples, by real‐time quantitative polymerase chain reaction, we have assessed the percentages of expression of the MyHC‐I, MyHC‐IIa, and MyHC‐IIx isoforms.ResultsThe mean MFL of the supraspinatus was longer (p = 0.001) and the PCSA was lower (p < 0.001) in Homo sapiens than in Pan troglodytes. Although the percentage of expression of MyHC‐IIa was lower in Homo sapiens than in Pan troglodytes (p = 0.035), the combination of MyHC‐IIa and MyHC‐IIx was expressed at a similar percentage in the two species.DiscussionThe longer MFL in the human supraspinatus is associated with a faster contractile velocity, which reflects the primary function of the upper limbs in Homo sapiens—the precise manipulation of objects—an adaptation to bipedal locomotion. In contrast, the larger PCSA in Pan troglodytes is related to the important role of the supraspinatus in stabilizing the glenohumeral joint during the support phase of knuckle‐walking. These functional differences of the supraspinatus in the two species are not reflected in differences in the expression of the MyHC isoforms.
The genome of an ancient Rouran individual reveals an important paternal lineage in the Donghu population
Authors: Li Jiawei , Zhang Ye , Zhao Yongbin , Chen Yongzhi , Ochir A. , Sarenbilige  , Zhu Hong , Zhou Hui 
Published: April 2018

AbstractObjectivesFollowing the Xiongnu and Xianbei, the Rouran Khaganate (Rouran) was the third great nomadic tribe on the Mongolian Steppe. However, few human remains from this tribe are available for archaeologists and geneticists to study, as traces of the tombs of these nomadic people have rarely been found. In 2014, the IA‐M1 remains (TL1) at the Khermen Tal site from the Rouran period were found by a Sino‐Mongolian joint archaeological team in Mongolia, providing precious material for research into the genetic imprint of the Rouran.Materials and methodsThe mtDNA hypervariable sequence I (HVS‐I) and Y‐chromosome SNPs were analyzed, and capture of the paternal non‐recombining region of the Y chromosome (NRY) and whole‐genome shotgun sequencing of TL1 were performed. The materials from three sites representing the three ancient nationalities (Donghu, Xianbei, and Shiwei) were selected for comparison with the TL1 individual.ResultsThe mitochondrial haplotype of the TL1 individual was D4b1a2a1. The Y‐chromosome haplotype was C2b1a1b/F3830 (ISOGG 2015), which was the same as that of the other two ancient male nomadic samples (ZHS5 and GG3) related to the Xianbei and Shiwei, which were also detected as F3889; this haplotype was reported to be downstream of F3830 by Wei et al. ().DiscussionWe conclude that F3889 downstream of F3830 is an important paternal lineage of the ancient Donghu nomads. The Donghu‐Xianbei branch is expected to have made an important paternal genetic contribution to Rouran. This component of gene flow ultimately entered the gene pool of modern Mongolic‐ and Manchu‐speaking populations.