bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH LATIHAN NAFAS DALAM TERHADAP PENINGKATAN SATURASI OKSIGEN PADA KLIEN TERPASANG WATER SEAL DRAINAGE (WSD) DI RSUD KABUPATEN TANGERANG
Authors: Yuningsih Yuningsih 
Published: May 2019

Di Indonesia kasus efusi pleura disebabkan oleh infeksi tuberkulosa. Tujuan umum penelitian ini terindentifikasi pengaruh nafas dalam terhadap saturasi oksigen pada klien terpasang WSD di RSU Kab.Tangerang. Penelitian ini merupakan penelitian pra eksperimen dengan rancangan penelitian yang digunakan pretest dan postest kelompok tunggal. Pada rancangan ini pengaruh efek atau treatmen diputuskan berdasarkan perbedaan antara pretest dan postest. Sampel yang digunakan sebanyak 20 orang. Menggunakan analisa data univariat dan bivariat. Hasil penelitian : Usia terbanyak pada responden dewasa pertengahan, klien bekerja, Jenis kelamin terbanyak: laki â€“ laki, Pendidikan : SMA. Lamanya penyakit : 1- 3 bulan. Rata-rata saturasi oksigen sebelum dilakukan nafas dalam pada pagi hari: 96,65 sedangkan setelah dilakukan nafas dalam pada siang hari : 97,62 denganÂ P value : 0,000 (P < 0,05) terdapat perbedaan yang signifikan saturasi oksigen antara sebelum dan setelah dilakukan nafas dalam. Variabel confounding tidak berpengaruh terhadap saturasi oksigen. Saran untuk perawat di ruang penyakit dalam : memberikan tindakan mandiri berupa nafas dalam agar ekspansi paru maksimal.
Pengaruh Pendidikan Kesehatan Terhadap Pengetahuan Deteksi Dini Dan Pencegahan Anemia Dalam Upaya Menurunkan Aki Pada Kader Posyandu
Authors: Solehati Tetti , Sari Citra Windani Mambang , Lukman Mamat , Kosasih Cecep Eli 
Published: May 2019

ABSTRAKLatar belakang: salah satu faktor penyebab masih tingginya angka mortalitas pada ibu antara lain anemiaÂ ibu hamil. Peran kader masyarakat yang tergabung dalam posyandu sangat diperlukan untuk ibu hamil dalam bentuk pendidikan kesehatan kepada ibu hamil untuk mengetahui pengaruh edukasi deteksi dini anemia terhadap pengetahuanÂ kader posyandu. Tujuan Penelitian: penelitian ini bertujuan untuk mengetahui pengaruh pendidikan kesehatan terhadap pengetahuan deteksi dini dan penceghan anemia pada kader posyandu. Metode: desain penelitian yang digunakan adalah quasi eksperimen dengan pretest dan post test without control. Pengambilan sampel dilakukan dengan metode total sampling sebanyak 21 kader kesehatan posyandu di Cipamokolan Kelurahan Mekarjaya Kecamatan Rancasari Bandung. Analisis data meliputi univariat dan bivariat dengan menggunakan uji t test. Hasil penelitian menunjukkan rata-rata tingkat pengetahuan sebelum intervensi dalam kategori kurangÂ (19%), cukup (76,2%), baik (4,8%) meningkat setelah intervensi menjadi cukup (14,3%) dan baik (85,7%). Pada analisis lanjut ditemukan rata-rata tingkat pengetahuan sebelum intervensi dari 60 menjadi 90 (p= 0.001). Kesimpulan: pendidikan kesehatan berpengaruh dalam meningkatkan tingkat pengetahuan kader kesehatan. Â Â tingkat pengetahuan kader kesehatan. Â ABSTRACTBackground: one of the contributing factors of high maternal mortality rate is pregnant mother's anemia. The role of community cadres incorporated in Posyandu is very necessary for pregnant women in the form of health education to pregnant women. Research Objectives: this study aimed to determine the effect of health education on knowledge of early detection of anemia and prevention of anemia of Posyandu cadres. Methods: the quasi experiment with pre test and post test without control design was used in this study. Sampling was collected by total sampling method as many as 21 health cadres of posyandu in Cipamokolan Kelurahan Mekarjaya, Rancasari District of Bandung. Data analysis included univariate and bivariate by using t-test. The results showed that the average level of knowledge before the intervention was in the category of less (19%), enough (76.2%), good (4.8%), it increased after intervention to enough (14.3%) and good (85.7 %). In the advanced analysis found that the average level of knowledge before the intervention was 60 to 90 (p = 0.001). Conclusion: health education is influential in increasing the level of health cadre knowledge
Persepsi Pasien/keluarga terhadap Mutu Pelayanan Rawat Jalan (Reliability, Assurance, Empathy) di RS Misi Lebak
Authors: Eko Natalia Sinaga Sarma 
Published: May 2019

Adapun tujuan penelitian ini adalah untuk melihat gambaran persepsi pasien terhadap mutu pelayanan RS Misi Lebak berdasarkan jenis kelamin, reliability (kehandalan) , assurance (jaminan) dan empathy (kepedulian). Penelitian dilakukan di pelayanan rawat jalan RS Misi Lebak. Metode penelitian ini adalah survey dengan pendekatan cross sectional, dengan jumlah sampel 110 orang yang merupakan pasien rawat jalan yang telah selesai mendapatkan pelayanan kesehatan. Â Pengumpulan data didapatkan melalui kuesioner kepuasan pasien, sedangkan analisa data yang dilakukan dengan menggunakan analisa Univariat, Bivariat Uji Chi-Square. Hasil uji statistika diperoleh ada hubungan yang signifikan antara reliability Â (P = 0.040), assurance (P = 0.000 ), empathy (P = 0.000 ) dengan persepsi terhadap mutu pelayanan rawat jalan.
PENGARUH METODE HEARTH DALAM MODIFIKASI DIET PADA BALITA DENGAN MALNUTRISI
Authors: Hadiyani Wini , Hendra Agus , Lindayani Linlin 
Published: May 2019

ModelÂ Tungku (Hearth) merupakan salah satu pendekatan yang efektif dalam mengatasi gizi buruk karena berbasis empowering dan pembelajaran bagi masyarakat bahwa dalam pemecahan masalah sosial sebenarnya solusi ada di dalam masyarakat itu sendiri. PenelitianÂ ini bertujuan untuk mengetahui pengaruh penerapan model tungku (Hearth) dalam meningkatkan status gizi balita malnutrisi melalui modifikasi diet. Jenis penelitian ini adalah Quasi eksperimen tanpa pembandingÂ denganÂ Â tehnik one group pre test and post testÂ design. Sampel didapatkan sebanyak 17 balita dengan tehnik purposive sampling. Status gizi balita dianalisa menggunakan pendekatanÂ standar antropometri balita berdasarkan ambang batas (Z-score). Hasil ujiÂ T menunjukkan adanya pengaruh model hearth terhadap status gizi balita dengan p value 0,00 (p < 0,05). Nilai beda didapatkan sebesar 1,482. Kesimpulannya adalah pendekatan model Hearth memberikan pengaruh yang signifikan terhadap perubahan status gizi pada balita malnutrisiÂ
Sistem Informasi Reservasi Restoran
Authors: Wicaksono Mochamad Fajar , Hamsir Intan Kurniawati 
Published: May 2019

Pada sistem reservasi sebelumnya yang bejudul “Perancangan Alat Reservasi Pada Restoran Berbasis Rasberry Pi dan Android”, pelanggan dapat melakukan reservasi restoran secara online dengan menggunakan aplikasi android berbasis raspberry pi. Setelah pembayaran berhasil maka server akan mengirimkan sebuah Qr code ke aplikasi pelanggan. Qr code tersebut digunakan oleh pelanggan untuk di scan ketika datang ke restoran untuk memverifikasi data pelanggan dengan data pada database server. Di mana qr code tersebut akan di scan pada qr code reader yang terdapat di setiap meja restoran. Berdasarkan sistem reservasi sebelumnya yang telah dijelaskan diatas maka dalam proses pengembangan sistem reservasi ini khususnya dalam proses verivikasi data pelanggan, kita tidak lagi menggunakan qr code yang discan dengan qr code reader. Dimana qr code reader ini terdapat di setiap meja restoran. Tentunya hal ini sangat boros biaya. Maka dari itu dalam sistem reservasi pengembangan ini, verifikasi data pelanggan akan menggunakan barcode yang akan di scan dengan barcode reader dimana barcode reader ini akan diletakan di pintu masuk restoran sehingga akan lebih mempermudah pelanggan ketika datang ke restoran dan tentunya dapat menghemat biaya. Selain itu juga pada sistem reservasi pengembangan ini ada sebuah fungsi tambahan pada aplikasi android dimana pelanggan tidak hanya dapat mereservasi meja saja tetapi pelanggan juga dapat ikut berjualan. Sehingga dengan demikian dapat mempermudah para pelanggan jika ingin membuka suatu usaha. Hasil pengujian terhadap masing-masing bagian sistem menunjukan bahwa sistem dapat bekerja dengan baik. Tingkat keberhasilan sistem resevasi online ini adalah 98%.

Kata kunci : reservasi, server, verifikasi, Barcode, Raspberry pi
Perancangan Sistem Informasi Perekrutan Karyawan Berbasis Web Menggunakan PHP dan MySQL DI PT. Ria Indah Mandiri
Authors: Rizky Ardelia Astriany , Ramdhani Irfan 
Published: May 2019

Penelitian ini bertujuan untuk menganalisis Sistem Informasi perekrutan Karyawan baru di PT Ria Indah Mandiri yang saat ini masih manual dan belum terkomputerisasi, dimana sistem perekrutan karyawan yang berjalan saat ini menyebabkan kurang efektifnya dalam proses penseleksian dan terjadinya penumpukan arsip lamaran kerja. Untuk mengatasi permasalahan tersebut dibangunlah Sistem Informasi Rekrutmen Karyawan Berbasis Web. Sistem Informasi yang dibangun ini menggunakan pemograman PHP dan MySQL database server. Metode pengembangan Perangkat Lunak yang digunakan adalah Waterfall, dengan Teknik pengumpulan data berupa Observasi, Kajian Pustaka dan Wawancara. Dengan Sistem Informasi baru ini diharapkan dapat membuat Proses Perekrutan Karyawan baru lebih Efektif dan Efisien baik dalam proses Penseleksian maupun Sistem Pengambilan keputusannya.
A Triple Origin for Twin Blue Stragglers in Close Binaries
Authors: Zwart Simon Portegies , Leigh Nathan W. C. 
Published: May 2019

Abstract
We propose that twin blue stragglers (BSs) in compact binaries evolve through mass transfer from a giant outer tertiary companion on to the inner binary. We apply this scenario to the twin BS binary WOCS ID 7782 in the old open cluster NGC 188. This binary has two comparable-mass main-sequence stars in a ≲10 days almost circular (e ≲ 0.1) orbit. Our theoretical arguments are supported by simulations of an inner binary that accretes from an outer Roche-lobe overfilling star using the Astrophysical Multipurpose Software Environment. At least 80% of the tertiary’s liberated mass accretes onto the inner binary via a circumbinary disk, turning both stars into BSs. Relatively stable mass transfer occurs for donors with ∼1.4 M
⊙ that overfill their Roche lobe before ascending the asymptotic giant branch. The system is best reproduced if this tertiary is in an 220–1100 days orbit around an inner binary composed of an 1.1 M
⊙ primary and a m
2 = 0.7–0.9 M
⊙ secondary in an 8.6–24 days orbit. The tertiary eventually turns into a 0.43–0.54 M
⊙ white dwarf in a relatively wide ≳5.8 yr orbit. The scenario is generic, but requires some fine-tuning to achieve parameters comparable to WOCS ID 7782. We predict that twin BSs formed through mass transfer from a Roche-lobe overfilling tertiary are generally comparable in mass with aligned spins, which are in turn aligned with the tertiary white dwarf’s orbit. If the two inner stars were initially unequal in mass the less massive star will accrete more, becoming more enhanced in CNO-processed material.
Modeling soil organic carbon dynamics in temperate forests with Yasso07
Authors: Mao Zhun , Derrien Delphine , Didion Markus , Liski Jari , Eglin Thomas , Nicolas Manuel , Jonard Mathieu , Saint-André Laurent 
Published: May 2019

Abstract. In a context of global changes, modeling and predicting the
dynamics of soil carbon stocks (CSs) in forest ecosystems are vital but challenging.
Yasso07 is considered to be one of the most promising models for such a purpose. We
examine the accuracy of its prediction of soil carbon dynamics over the whole
French metropolitan territory at a decennial timescale. We used data from 101 sites in the RENECOFOR network, which encompasses most
of the French temperate forests. These data include (i) the quantity of
above-ground litterfall from 1994 to 2008, measured yearly, and (ii) the soil
CSs measured twice at an interval of approximately 15 years (once
in the early 1990s and around 2010). We used Yasso07 to simulate the annual
changes in carbon stocks (ACCs; in tC ha−1 yr−1) for each site and then
compared the estimates with actual recorded data. We carried out
meta-analyses to reveal the variability in litter biochemistry in different
tree organs for conifers and broadleaves. We also performed sensitivity
analyses to explore Yasso07's sensitivity to annual litter inputs and model
initialization settings. At the national level, the simulated ACCs
(+0.00±0.07 tC ha−1 yr−1, mean ± SE) were of the same
order of magnitude as the observed ones (+0.34±0.06 tC ha−1 yr−1). However, the correlation between predicted
and measured ACCs remained weak (R2<0.1). There was significant
overestimation for broadleaved stands and underestimation for coniferous
sites. Sensitivity analyses showed that the final estimated CS was
strongly affected by settings in the model initialization, including litter
and soil carbon quantity and quality and also by simulation length. Carbon
quality set with the partial steady-state assumption gave a better fit than
the model with the complete steady-state assumption. With Yasso07 as the support model, we showed that there is currently a
bottleneck in soil carbon modeling and prediction due to a lack of
knowledge or data on soil carbon quality and fine-root quantity in the
litter.
What Are the Contemporary Etiologies for Revision Surgery and Revision After Primary, Noncemented Total Hip Arthroplasty?
Authors: Ledford Cameron K. , Perry Kevin I. , Hanssen Arlen D. , Abdel Matthew P. 
Published: May 2019

Introduction:
Contemporary failure etiologies of primary total hip arthroplasties (THAs) have not been precisely defined because of heterogeneity of referral practices.

Methods:
A single-institution registry of 4,555 primary, noncemented THAs performed by subspecialty trained arthroplasty surgeons between 2000 and 2012 was analyzed. Only revision surgeries and revisions that occurred after THAs initially performed at the institution were included.

Results:
The estimated 10-year survivorships free from THA revision surgery, modular implant revision, and nonmodular implant revision were 98.2%, 98.1%, and 96.3%, respectively. The most common reasons for revision surgeries were wound-related complications (49%), periprosthetic fracture (25%), and pain (18%). Hip instability (53%) and acute periprosthetic joint infection (26%) were the most common etiologies of revision procedures with isolated exchange of at least one modular implant. The most common reasons for replacement or removal of nonmodular implant were periprosthetic fracture (32%), aseptic loosening (22%), and adverse tissue reaction (17%).

Discussion:
Focusing on primary THAs initially performed by a contemporary, subspecialty practice allowed an accurate determination of etiologies and rates of failure (defined by revision surgery or revision) after THA.

Level of Evidence:
Level IV
A Step in the Right Direction: Body Location Determines Activity Tracking Device Accuracy in Total Knee and Hip Arthroplasty Patients
Authors: Goel Rahul , Danoff Jonathan R. , Petrera Matteo , Blevins Kier , Purtill James J. , Chen Antonia F. 
Published: May 2019

Introduction:
Step counts measured by activity monitoring devices (AMDs) and smartphones (SPs) can objectively measure a patient's activity levels after total hip and knee arthroplasty (total joint arthroplasty [TJA]). This study investigated the use and optimal body location of AMDs and SPs to measure step counts in the postoperative period.

Methods:
This was a two-armed, prospective, observational study of TJA inpatients (n = 24) and 2-week status after TJA (n = 25) completing a 100-ft walk. Observer-counted steps were compared with those measured by AMDs (wrist and ankle) and SPs (hip and neck). Acceptable error was defined as <30%. Error rates were treated as both dichotomous and continuous variables.

Results:
AMD and SP step counts had overall unacceptable error in TJA inpatients. AMDs on the contralateral ankle and SPs on the contralateral hip had error rates less than 30% at 2 weeks postoperatively. Two-week postoperative patients required lower levels of assist (11/25 walker; 4/25 no assist), and significant improvements in stride length (total hip arthroplasty 1.27 versus 1.83 ft/step; total knee arthroplasty 1.42 versus 1.83 ft/step) and cadence (total hip arthroplasty 74.6 versus 166.0 steps/min; total knee arthroplasty 73.5 versus 144.4 steps/min) were seen between inpatient and postoperative patients. Regression analysis found that increases in postoperative day and cadence led to a decrease in device error.

Conclusion:
In inpatients with TJA, AMDs and SPs have unacceptable variability and limited utility for step counting when using a walker. As gait normalizes and the level of ambulatory assist decreases, AMDs on the contralateral ankle and SPs on the contralateral hip demonstrated low error rates. These devices offer a novel method for measurement of objective outcomes and potential for remote monitoring of patient progress after TJA.

Level of evidence:
Level II, prospective, three-armed study, prognostic study
The key genes involved in herpes simplex virus-1 corneal infection-induced acute hepatitis
Authors: Hu Kai , Li Jinlong , Yuan Xianwen 
Published: May 2019

Background: Viral keratitis is mainly induced by herpes simplex virus (HSV). HSV-1 infection-induced acute hepatitis associates with immunodeficiency. Related biomarkers have not been systemically identified till now. This study was designed to explore the molecular mechanisms and potential biomarkers of HSV-1 infection-induced acute hepatitis.
Methods: Microarray dataset GSE35943, including the liver tissues infected by HSV-1 (1, 3, 5, and 7 days post infection) and the corresponding control tissues, was extracted from Gene Expression Omnibus database. The differentially expressed genes (DEGs) were identified using and were clustered using time series expression analysis. DEG-associated KEGG pathways were called using online DAVID tool. Using Cytoscape software, protein-protein interaction (PPI) network was built and significant network modules were identified.
Results: A total of 2909 DEGs grouping into 3 clusters with similar gene expression profiles were obtained. The DEGs were involved in immune-associated functional terms and pathways like natural killer cell mediated cytotoxicity and antigen processing and presentation. DEGs including PIK3R1, PIK3CD, PLCG2, PTPN6, LCK, RAC2, and PLK1 had higher degrees in the PPI network and 8 significant modules
Conclusion: PIK3R1, PIK3CD, PLCG2, PTPN6, LCK, RAC2 and PLK1 were identified to be associated with HSV-1 corneal infection-induced hepatitis, and might be potential clinical biomarkers for the diagnosis of HSV-1-induced hepatitis.
Fibrinogen‐Based Hydrogel Modulus and Ligand Density Effects on Cell Morphogenesis in Two‐Dimensional and Three‐Dimensional Cell Cultures
Authors: Yosef Andrei , Kossover Olga , Mironi‐Harpaz Iris , Mauretti Arianna , Melino Sonia , Mizrahi Joseph , Seliktar Dror 
Published: May 2019

AbstractThere is a need to further explore the convergence of mechanobiology and dimensionality with systematic investigations of cellular response to matrix mechanics in 2D and 3D cultures. Here, a semisynthetic hydrogel capable of supporting both 2D and 3D cell culture is applied to investigate cell response to matrix modulus and ligand density. The culture materials are fabricated from adducts of polyethylene glycol (PEG) or PluronicF127 and fibrinogen fragments, formed into hydrogels by free‐radical polymerization, and characterized by shear rheology. Control over the modulus of the materials is accomplished by changing the concentration of synthetic PEG‐diacrylate crosslinker (0.5% w/v), and by altering the molecular length of the PEG (10 and 20 kDa). Control over ligand density is accomplished by changing fibrinogen concentrations from 3 to 12 mg mL−1. In 2D culture, cell motility parameters, including cell speed and persistence time are significantly increased with increasing modulus. In both 2D and 3D culture, cells express vinculin and there is evidence of focal adhesion formation in the high stiffness materials. The modulus‐ and ligand‐dependent morphogenesis response from the cells in 2D culture is contradictory to the same measured response in 3D culture. In 2D culture, anchorage‐dependent cells become more elongated and significantly increase their size with increasing ligand density and matrix modulus. In 3D culture, the same anchorage‐dependent cells become less spindled and significantly reduce their size in response to increasing ligand density and matrix modulus. These differences arise from dimensionality constraints, most notably the encapsulation of cells in a non‐porous hydrogel matrix. These insights underscore the importance of mechanical properties in regulating cell morphogenesis in a 3D culture milieu. The versatility of the hydrogel culture environment further highlights the significance of a modular approach when developing materials that aim to optimize the cell culture environment.
In Vitro and In Vivo Antimicrobial Activity of Antibiotic‐Conjugated Carriers with Rapid pH‐Responsive Release Kinetics
Authors: Kang Sunyoung , Park Gee Ho , Kim Seulah , Kim Jungah , Choi Yoonhwa , Huang Yan , Lee Yan , Choi Tae Hyun 
Published: May 2019

AbstractTwo representative antibiotics, cephradine (CP) and moxifloxacin (MX), are covalently conjugated with a β‐cyclodextrin (β‐CD)‐based carrier via pH‐responsive 1‐methyl‐2‐(2′‐carboxyethyl) maleic acid amide (MCM) linkers with excellent conjugation efficiency via simple mixing. At pH 5.5, 90% and 80% of the CP and MX, respectively, are released from the carriers within 30 min, in contrast with the much‐delayed release profile at pH 7.4. The in vitro inhibitory effect of β‐CD–MCM–CP on the growth of Staphylococcus aureus is significantly lower than that of free CP at pH 7.4, but it reaches the level of free CP at pH 5.5. Moreover, S. aureus develops significant CP resistance after pretreatment with free CP, whereas the initial CP sensitivity is maintained after pretreatment with β‐CD–MCM–CP at pH 7.4. However, β‐CD–MCM–MX exhibits no such pH‐responsive activity against Bacteroides fragilis, probably due to the insufficient stability of the MX conjugation at pH 7.4. In nondiabetic and diabetic mouse models, β‐CD–MCM–CP significantly reduces the subcutaneous abscess scores and the bacterial counts in the abscess, although this represents only a marginal improvement in antimicrobial activity compared to free CP.
Bioinspired Viscoelastic Capsules: Delivery Vehicles and Beyond
Authors: Etienne Gianluca , Ong Irvine Lian Hao , Amstad Esther 
Published: May 2019

AbstractMicrocapsules are often used as individually dispersed carriers of active ingredients to prolong their shelf life or to protect premature reactions with substances contained in the surrounding. This study goes beyond this application and employs microcapsules as principal building blocks of macroscopic 3D materials with well‐defined granular structures. To achieve this goal and inspired by nature, capsules are fabricated from block‐copolymer surfactants that are functionalized with catechols, a metal‐coordinating motive. These surfactants self‐assemble at the surface of emulsion drops where they are ionically cross‐linked to form viscoelastic capsules that display a low permeability even toward small encapsulants. It is demonstrated that the combination of the mechanical strength, flexibility, and stickiness of the capsules enables their additive manufacturing into macroscopic granular structures. Thereby, they open up new opportunities for 3D printing of soft, self‐healing materials composed of individual compartments that can be functionalized with different types of spatially separated reagents.