bluuebunny/crossref_metadata_2025_split huggingface dataset:
Septicemia por amebíase em uma lactente jovem: um relato de caso
Authors: Silva Joice Maely Souza da , Costa Larah Lins , Azevedo Maria Izabel Lencastre Menezes Dourado , Filho Arlindo Francisco da Silva , Cabral Fernando Henrique de Siqueira 
Published: November 2024

A amebíase é uma a infecção causada pelo protozoário Entamoeba histolytica. Constitui-se em um problema de saúde pública, em nível mundial, de infecções intestinais causadas por protozoários. O objetivo do estudo visa relatar um caso de lactente, contaminada por amebíase e suas consequências sistêmicas. Trata-se de um estudo do tipo relato de caso, em que os dados foram coletados a partir da análise de prontuário e revisão da literatura. Os resultados revelam paciente, sexo feminino, de 1 mês e 14 dias, peso 2765g, residente em zona rural de Pernambuco, deu entrada na emergência com quadro de hipoglicemia e desidratação. Foi submetida a exame parasitológico de fezes, sendo encontrados cistos e trofozoítos de Entamoeba histolytica/díspar. Após esquema com metronidazol 45 mg/kg/dia, durante 10 dias, apresentou piora do quadro clínico, evoluindo com injúria renal, estridor respiratório persistente, sendo necessária intubação orotraqueal (TOT 3,5) por 6 dias, com posterior redução da mobilidade das pregas vocais, distensão abdominal significativa e crise convulsiva. Na ultrassonografia transfontanelar, observou-se alteração da artéria mediana do corpo caloso e índice de resistência (0,58), sugerindo lesão da substância branca. Após 5 semanas de internamento, evoluiu com melhora clínica. Mais adiante, houve nova piora com desconforto respiratório, abordada nova IOT, sendo essa a quarta ventilação mecânica invasiva. Após acompanhamento multidisciplinar, evoluiu com melhora do quadro. Obteve alta hospitalar após 77 dias. Diante do caso em questão, nota-se que a amebíase de foco extra-intestinal, caso raro, principalmente em neonatos, pode trazer repercussões significativas na qualidade de vida dos pacientes acometidos.
Evaluación de la Calidad Educativa: Un Estudio Descriptivo sobre Competencias Docentes y Metodologías de Enseñanza
Authors: Gómez Méndez Maira Virginia 
Published: November 2024

La calidad docente se refiere a la capacidad de los maestros para impartir educación de manera efectiva, logrando resultados positivos en el aprendizaje de los estudiantes. El objetivo de este estudio fue analizar los criterios de calidad en la enseñanza. En cuanto al método es un estudio descriptivo transversal en una cohorte de 525 estudiantes del municipio Chiantla, Huehuetenango. Los resultados indican que la mayoría de los docentes cumple consistentemente con los criterios evaluados. El 91.43% planifica y socializa sus clases adecuadamente. En cuanto al desarrollo de competencias, el 77.72% lo cumple. El 88.38% explica los temas con claridad. El 81.14% refuerza aprendizajes difíciles, el 72.57% motiva y desarrolla el autoconocimiento, y el 80.96% emplea estrategias didácticas de manera efectiva. En conclusión, los docentes muestran altos niveles de cumplimiento en las competencias evaluadas, destacando especialmente en la planificación de clases y la claridad en la explicación de temas.
Estrategias de marketing para impulsar la competitividad y las oportunidades comerciales en el contexto internacional
Authors: Fletcher Calipolitti Nieves , De León Jaén Orquídea , Saavedra Núñez Rosario 
Published: November 2024

El marketing se enfrenta a desafíos significativos que se vuelven más complejos cuando las empresas tienen que proyectarse en el contexto de los mercados internacionales. Con el objetivo de describir tres estrategias para impulsar la competitividad y las oportunidades comerciales en el contexto internacional, se realizó un ejercicio hipotético basado en tres de las soluciones propuestas por Kotler a tres errores que cometen las empresas en marketing y que son considerados críticos, porque impiden su éxito y competitividad. El diseño de la investigación es descriptivo, no experimental y transversal, utilizando un enfoque mixto; la población y muestra son hipotéticas, ya que el estudio es un ejercicio teórico para evaluar estrategias de marketing en empresas internacionales en América, Europa y Asia, centradas en la segmentación del mercado, el conocimiento del cliente y el análisis de la competencia. El resultado más importante del estudio fue la identificación de la necesidad que tienen las empresas de personalizar las estrategias de marketing a las características y preferencias específicas de cada mercado internacional, para mejorar la competitividad y ampliar las oportunidades comerciales en diversas regiones del mundo. Así mismo, se concluye que, para impulsar la competitividad y las oportunidades comerciales en el contexto internacional, se debe saber convertir los errores en oportunidades.
The Influence of Brand Image, and Sharia Label on Savings Decisions of Customers at PT Bank Syariah Indonesia Tbk KCP Jember Gajah Mada
Authors: Arlian Ludita Cosa , Masrohatin Siti , Setianingrum Nurul , Qoriani Hersa Farida , Chotib Moch. 
Published: November 2024

This study aims to analyze the effect of brand image and sharia label on saving decisions on customers of PT Bank Syariah Indonesia Tbk KCP Jember Gajah Mada. Bank Syariah Indonesia is one of the largest Islamic financial institutions in Indonesia that provides banking products and services according to sharia principles. Factors such as brand image and the existe nce of sharia labels are considered to have an important role in influencing customer decisions to save at Islamic banks. The research method used is quantitative with data collection techniques through questionnaires distributed to Bank Syariah Indonesia customers at KCP Jember Gajah Mada. The data obtained were analyzed using multiple linear regression to determine the effect of each independent variable on saving decisions. The results showed that brand image, and sharia label simultaneously and partially had a significant effect on customer saving decisions. Brand image has a positive and significant effect, which shows that the positive image of Islamic banks can increase customer interest in saving. In addition, the sharia label, which shows compliance with sharia principles, also makes a significant contribution in influencing customer decisions. In conclusion, brand image, and sharia label are important factors that influence customer decisions in saving at Bank Syariah Indonesia. Therefore, the bank is expected to continue to strengthen the brand image, provide education about sharia products, and maintain the integrity of the sharia label to increase customer loyalty and trust.
Pengaruh Penjualan Kredit dan Perputaran Piutang terhadap Profitabilitas Periode Sebelum dan Saat Covid-19
Authors: R. Enough Bhaktiar  , Nia Kusniati  
Published: November 2024

The research was conducted on companies in the cosmetics and household needs subsector listed on the Indonesia Stock Exchange in 2015-2021. This type of research uses quantitative methods samples selected using purposive techniques. Data analysis is done using panel data regression with the help of the Eviews 12 program. The research results indicate that partially, Credit Sales and Accounts Receivable Turnover has no effect on profitability, while simultaneously, Credit Sale and Accounts Receivable Turnover show a positive and significant effect on profitability (return on asset) with a determination coefficient of 0,631977 or 63,1977% then the remaining 0,368023 or 36,8023% is influenced by other variables that are outside this study.
Analisis Pengaruh Rasio-Rasio Keuangan Terhadap Rasio Beban Operasional-Pendapatan Operasional (BOPO) pada Bank Umum Syariah di Indonesia
Authors: Amri Darma Kurniawan S  , Rusiadi Rusiadi  , Bakhtiar Efendi  , Lia Nazliana Nasution  
Published: November 2024

This research aims to determine the influence of Islamic banking financial ratios in the form of Return on Assets (ROA) Ratio, Non Performing Financing (NPF) Ratio, Financing to Deposit Ratio (FDR) and Total Asset Turnover (TATO) on the Operational Cost-Operational Income Ratio (BOPO) at Sharia Commercial Banks in Indonesia. This research uses a quantitative approach with sample data totaling 7 (seven) sharia commercial banks out of 13 (thirteen) sharia commercial bank populations registered with the Financial Services Authority. Research data uses secondary data for the annual period in the period 2010 - 2023. By using the ARDL (Autoreggressive Distributed Lag) panel model using the PMG (Pooled Mean Group) method, the research results show that in the panel, it turns out that the Leading Indicator is the effectiveness of the variable in controlling the BOPO Ratio at Sharia Commercial Banks in Indonesia is Return on Assets (ROA), where ROA significantly influences the BOPO Ratio at Bank Muamalat Indonesia, Bank Aceh Syariah, Bank Riau Kepri Syariah, Bank Jabar Banten Syariah, Bank Mega Syariah, and Bank NTB Syariah, with stable positions in the short and long term. Of the 7 (seven) Sharia Commercial Banks that are the objects of research, there are 4 (four) banks that are leading indicators of the effectiveness of sharia banking in influencing the stability of the BOPO ratio, namely: Bank Aceh Syariah, Bank Riau Kepri Syariah, Bank Jabar Banten Syariah, and Bank Mega Syariah through ROA, NPF, FDR, and TATO. Financing to Deposit Ratio (FDR) is also capable of being a Leading Indicator of variable effectiveness to influence the BOPO Ratio at Bank Muamalat Indonesia, Bank Aceh Syariah, Bank Riau Kepri Syariah, Bank BCA Syariah, Bank Jabar Banten Syariah, Bank Mega Syariah, and Bank NTB Syariah, However, its position is unstable in the short and long term.
Pengaruh Pengetahuan Akuntansi dan Tingkat Pendidikan Terhadap Laporan Keuangan di Sekolah Menengah Pertama Swasta Wilayah Subrayon 05 Kabupaten Bekasi
Authors: Siti Syafa'at  , Dany Prio Hutomo  
Published: November 2024

Developing countries are countries that value education, but in improving the quality of education services there are gaps in accounting information, such as financial reports which need attention and improvement in their services. The purpose of this study was to determine whether accounting knowledge and education level affect the quality of financial reporting at private secondary schools in Soubrayon 05 Bekasi Regency. This research is quantitative, with a population of twenty-nine schools in the region and sample data taken using a questionnaire according to purposive sampling technique with a total of 51 people. The data analysis technique used is multiple regression analysis, classical assumptions and hypotheses. The results of this study indicate that all are valid and reliable, with the accounting knowledge variable showing a significance value of 0.014 below 0.05, and the education level variable showing a significance value of 0.006 below 0.05, which means each is accepted and shows there is an influence on the quality of financial statements. The simultaneous test results also show a significance value of 0.011 below 0.05 where Accounting Knowledge and Education Level together have a significant effect on the Quality of Financial Statements.
Dampak Profitabilitas Sebagai Variabel Moderasi terhadap Pengaruh Praktik Tata Kelola Perusahaan Yang Baik dan Tanggung Jawab Sosial Perusahaan Terhadap Nilai Perusahan
Authors: Muhamad Soleh Rizky  , Prita Andini  
Published: November 2024

This study was conducted to examine the influence of good corporate governance with proxies by managerial ownership, institutional ownership and independent commissioners as well as corporate social responsibility with profitability as a moderation variable on company value. The sample selection technique in this study uses purposive sampling and was obtained from 11 retail companies listed on the Indonesia Stock Exchange for the 2019-2023 period. The data analysis used in this study is multiple linear regression analysis using SPSS software version 27. Based on the results of the study, it can be concluded that managerial ownership and CSR have no effect on company value, institutional ownership and independent commissioners have a positive effect on company value, profitability cannot moderate the influence of managerial ownership and CSR on company value, and profitability can weaken the influence of institutional ownership and independent commissioners on company value.
Quasi‐Amorphous Metallic Nickel Nanopowder as an Efficient and Durable Electrocatalyst for Alkaline Hydrogen Evolution
Authors: Zhang Doudou , Shi Jingying , Qi Yu , Wang Xiaomei , Wang Hong , Li Mingrun , Liu Shengzhong , Li Can 
Published: October 2018

AbstractNickel is regarded as the best alternative metal electrocatalyst to platinum for hydrogen evolution reaction (HER). Success in developing a quasi‐amorphous metallic nickel (QAMN) nanopowder catalyst using a two‐step chemical route for efficient and durable HER in alkaline solution is reported. It is found that the QAMN electrocatalyst exhibits essentially zero overpotential at the cathodic onset while delivering 10 mA cm−2 at an overpotential of only 240 mV; both performances are far better than what was reported previously using prior metallic nickel catalysts. Taking into account increased surface area, further enhanced activity is attributed to the superior intrinsic activity. Meanwhile, the QAMN catalyst shows excellent stability in accelerated and interrupted polarization in alkaline solution for tens of hours. This study provides a new chemical means to prepare amorphous metallic materials for more efficient catalysis.
Adult leukemia survival trends in the United States by subtype: A population‐based registry study of 370,994 patients diagnosed during 1995‐2009
Authors: Bailey Chris , Richardson Lisa C. , Allemani Claudia , Bonaventure Audrey , Harewood Rhea , Moore Angela R. , Stewart Sherri L. , Weir Hannah K. , Coleman Michel P. ,   CONCORD Working Group (US members)
Published: October 2018

AbstractBACKGROUNDThe lifetime risk of developing leukemia in the United States is 1.5%. There are challenges in the estimation of population‐based survival using registry data because treatments and prognosis vary greatly by subtype. The objective of the current study was to determine leukemia survival estimates in the United States from 1995 to 2009 according to subtype, sex, geographical area, and race.METHODSFive‐year net survival was estimated using data for 370,994 patients from 43 registries in 37 states and in 6 metropolitan areas, covering approximately 81% of the adult (15‐99 years) US population. Leukemia was categorized according to principal subtype (chronic lymphocytic leukemia, acute myeloid leukemia, and acute lymphocytic leukemia), and subcategorized in accordance with the HAEMACARE protocol. We analyzed age‐standardized 5‐year net survival by calendar period (1995‐1999, 2000‐2004, and 2005‐2009), leukemia subtype, sex, race, and US state.RESULTSThe age‐standardized 5‐year net survival estimates increased from 45.0% for patients diagnosed during 1995‐1999 to 49.0% for those diagnosed during 2000‐2004 and 52.0% for those diagnosed during 2005‐2009. For patients diagnosed during 2005‐2009, 5‐year survival was 18.2% (95% confidence interval [95% CI], 17.8%‐18.6%) for acute myeloid leukemia, 44.0% (95% CI, 43.2%‐44.8%) for acute lymphocytic leukemia, and 77.3% (95% CI, 76.9%‐77.7%) for chronic lymphocytic leukemia. For nearly all leukemia subtypes, survival declined in successive age groups above 45 to 54 years. Men were found to have slightly lower survival than women; however, this discrepancy was noted to have fallen in successive calendar periods. Net survival was substantially higher in white than black patients in all calendar periods. There were large differences in survival noted between states and metropolitan areas.CONCLUSIONSSurvival from leukemia in US adults improved during 1995‐2009. Some geographical differences in survival may be related to access to care. We found disparities in survival by sex and between black and white patients.
Evaluation of holographic imaging cytometer holomonitor M4® motility applications
Authors: Zhang Yuntian , Judson Robert L. 
Published: October 2018

AbstractDigital holographic cytometry (DHC) and other methods of quantitative phase imaging permit extended time‐lapse imaging of mammalian cells in the absence of induced cellular toxicity. Manufactured DHC platforms equipped with semi‐automated image acquisition, segmentation, and analysis software packages (or modules) for assessing cell behavior are now commercially available. When housed in mammalian cell incubators these cytometers offer the potential to monitor and quantify a range of cellular behaviors without disrupting routine culture. Realization of this potential requires validation against established standards. Two proprietary software modules for assessing cellular motility available using the HoloMonitor M4 DHC platform were evaluated on human melanoma cells lines with known relative motility and metastatic potential. One such software package, the Track Cells module, was run during routine culture. In addition, the Wound Healing module was conducted in parallel with established transwell migration and invasion assays. Each module was evaluated for reproducibility and correlation to established assays. Both software modules reliably recorded increased cellular motility in the metastatic 1205Lu line as compared with the non‐metastatic WM793 line. In a direct comparison of the two propriety DHC software modules and two established transwell assays, the relative cell motilities were well correlated. The granularity of data provided by the Track Cells module permitted the additional identification of rare hyper‐motile cells in the metastatic population and the distinction of motility from division associated displacement. The two HoloMonitor M4 DHC proprietary software modules for assessing cellular motility yielded reproducible results that were well‐correlated with established standards. © 2018 International Society for Advancement of Cytometry
Inhibiting conjugation as a tool in the fight against antibiotic resistance
Authors: Graf Fabrice E. , Palm Martin , Warringer Jonas , Farewell Anne 
Published: October 2018

AbstractAntibiotic resistance, especially in gram‐negative bacteria, is spreading globally and rapidly. Development of new antibiotics lags behind; therefore, novel approaches to the problem of antibiotic resistance are sorely needed and this commentary highlights one relatively unexplored target for drug development: conjugation. Conjugation is a common mechanism of horizontal gene transfer in bacteria that is instrumental in the spread of antibiotic resistance among bacteria. Most resistance genes are found on mobile genetic elements and primarily spread by conjugation. Furthermore, conjugative elements can act as a reservoir to maintain antibiotic resistance in the bacterial population even in the absence of antibiotic selection. Thus, conjugation can spread antibiotic resistance quickly between bacteria of the microbiome and pathogens when selective pressure (antibiotics) is introduced. Potential drug targets include the plasmid‐encoded conjugation system and the host‐encoded proteins important for conjugation. Ideally, a conjugation inhibitor will be used alongside antibiotics to prevent the spread of resistance to or within pathogens while not acting as a growth inhibitor itself. Inhibiting conjugation will be an important addition to our arsenal of strategies to combat the antibiotic resistance crisis, allowing us to extend the usefulness of antibiotics.
Comparison of the quality of dried persimmon (Diospyros kaki THUNB.) treated with medicinal plant extracts and food additives
Authors: Kim Jun‐Hoi , Chung Il Kyung , Kim Hak Yoon , Kim Kyung‐Min 
Published: October 2018

AbstractWe evaluated the direct application of different extracts from plant‐derived compounds at different ratios. The best effect was observed with the combination of 18.18% clove, 9.90% cinnamon, 9.09% licorice, 4.55% firmament, 4.55% grapefruit seed extract, and 54.54% apple cider vinegar. The combination of these compounds improved the moisture content of the fruit and showed antifungal, antibrowning, and antifungal/antibrowning effects as compared with the control following 6‐week treatment. The treatment resulted in an increase in the overall sugar concentration of dried persimmons. Antibrowning/antifungal test showed high sugar content of 30–39 °brix. The hardness of the treatment groups was similar to that of the control and decreased by 0.5 to 0.8 after 6 weeks. The evaluation of color change revealed a decreasing tendency in the value of △E during the drying period. Thus, natural extracts effectively suppressed the quality degradation during drying of persimmon and may be used to replace sulfur fumigation.
Acute exposure to organic and inorganic sources of copper: Differential response in intestinal cell lines
Authors: Keenan Joanne , O'Sullivan Finbarr , Henry Michael , Breen Laura , Doolan Padraig , Sinkunaite Indre , Meleady Paula , Clynes Martin , Horgan Karina , Murphy Richard 
Published: October 2018

AbstractScopeCopper supplementation in nutrition has evolved from using inorganic mineral salts to organically chelated minerals but with limited knowledge of the impact at the cellular level.MethodsHere, the impact of inorganic and organic nutrient forms (glycinate, organic acid, and proteinate) of copper on the cellular level is investigated on intestinal cell lines,HT29 and Caco‐2, after a 2‐hr acute exposure to copper compounds and following a 10‐hr recovery.ResultsFollowing the 10‐hr recovery, increases were observed in proteins involved in metal binding (metallothioneins) and antioxidant response (sulfiredoxin 1 and heme oxygenase 1), and global proteomic analysis suggested recruitment of the unfolded protein response and proteosomal overloading. Copper organic acid chelate, the only treatment to show striking and sustained reactive oxygen species generation, had the greatest impact on ubiquitinated proteins, reduced autophagy, and increased aggresome formation, reducing growth in both cell lines. The least effect was noted in copper proteinate with negligible impact on aggresome formation or extended growth for either cell line.ConclusionThe type and source of copper can impact significantly at the cellular level.