bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-sectoral rehabilitation intervention for patients with intermittent claudication versus usual care for patients in non-operative management - The CIPIC Rehab study: study protocol for a randomised controlled trial
Authors: Siercke Maj , Jørgensen Lise Pyndt , Missel Malene , Thygesen Lau Caspar , Blach Pernille Peppercorn , Sillesesn Henrik , Berg Selina Kikkenborg 
Published: August 2019

Abstract
Introduction: Intermittent claudication (IC) caused by Peripheral Artery Disease (PAD) is a common cardiovascular disease. Patients with IC have reduced walking capacity, restricted activity levels and mobility, and reduced health-related quality of life. The disease leads to social isolation, the risk of cardiovascular morbidity, and mortality. Non-operative management of IC requires exercise therapy and studies show that supervised exercise training is more effective than unsupervised training, yet many patients with IC lack motivation for changes in health behavior. No studies investigating the effects of existing cardiac rehabilitation targeted patients with IC have been published. The aim of this paper is to present the rationale and design of the CIPIC Rehab Study, which examines the effect of a cross-sectoral rehabilitation programme versus usual care for patients in non-operative management for IC. Methods and analysis: A randomised clinical trial aims to investigate whether cardiac rehabilitation for patients with IC in non-operative management versus usual care is superior to treatment as usual. The trial will allocate 118 patients, 1:1 individual randomisation to either the intervention or control group. The primary outcome is maximal walking distance measured by the standardised treadmill walking test. The secondary outcome is pain-free walking distance measured by the standardised treadmill walking test, healthy diet measured by a fat-fish-fruit-green score, and level of physical activity measured by activity score within official recommendations. Statistical analyses will be blinded. Several exploratory analyses will be performed. A mixed-method design is used to evaluate qualitative and quantitative findings. A qualitative and a survey-based complementary study will be undertaken to investigate patients’ post-discharge experiences. A qualitative post-intervention study will explore experiences of participation in rehabilitation. Discussion: The study is the first to assess the effect of a cardiac rehabilitation programme designed for patients with intermittent claudication. The study will describe how to monitor and improve rehabilitations programme for patients with intermittent claudication in a real-world setting. Mixed method strategies can allow for both exploration and generalization in the same study, but the research design is a complex intervention and any effects found can not be awarded a specific component.
Vision status of children aged 7 - 15 years referred from school vision screening in Norway during 2003 - 2013: a retrospective study
Authors: Falkenberg Helle K , Langaas Trine , Svarverud Ellen 
Published: August 2019

Abstract
Background: Undetected vision problems is an important cause of reduced academic achievement, performance in everyday life and self-esteem. This receives little attention in national health care services in Norway even though most of these vision problems are easily correctable. There are no published data on how many Norwegian schoolchildren are affected by correctable vision problems. This study aims to determine the vision status in primary and secondary schoolchildren referred from vision screening during the 10 year period of 2003 -2013.
Methods: Of the 1126 children (15%) aged 7 - 15 years referred to the university eye clinic by the school screening program, all 782 who attended the eye clinic were included in the study. Patient records were retrospectively reviewed with regard to symptoms, refractive error, best corrected visual acuity (BCVA) of logMAR, binocular vision, ocular health and management outcomes.
Results: Previously undetected vision problems were confirmed in 650 (83%) of the children. The most frequent outcomes were glasses (346) or follow-up (209), but types of treatment modalities varied with age. Mean refractive errors were hyperopic for all age groups but reduced with age (ANOVA, p < 0.001). Overall, 51% were hyperopic, 32% emmetropic and 17% myopic. Refractive errors did not change across the decade (linear regression, all p > 0.05). Mean logMAR BCVAs were better than 0.0 and improved with age (ANOVA, p < 0.001). The most prevalent symptoms were headaches (171), near vision problems (149) and reduced distance vision (107).
Conclusions: The vision screening identified children with previously undetected visual problems. This study shows that the types of visual problems varied with age and that most problems could be solved with glasses. Our results stress the importance of regular eye examinations and that vision examinations should be included in primary health care services. Furthermore, there is a need for raised awareness among parents and teaching staff regarding vision problems in children.
MULTIPLEX qPCR FACILITATES IDENTIFICATION OF BETAHERPESVIRUSES IN PATIENTS WITH ACUTE LIVER FAILURE OF UNKNOWN ETIOLOGY
Authors: Raposo Jéssica Vasques , Alves Arthur Daniel Rocha , Silva Alexandre Dos Santos Da , Santos Damião Carlos Dos , Melgaço Juliana Gil , Moreira Otacilio Cruz , Pinto Marcelo Alves , de Paula Vanessa 
Published: August 2019

Abstract
Background: The etiology of acute liver failure (ALF) is often unknown and reported to be associated with herpesviruses in a number of cases. In this study, we examined for betaherpesviruses infections in patients with ALF of unknown etiology using a multiplex qPCR to Betaherpesviruses subfamily.
Methods: Liver explant and serum samples from 27 patients with ALF of unknown etiology were analyzed with the aid of multiplex qPCR to identify betaherpesviruses. All positive samples were sequenced to confirm herpes infection and liver enzyme levels evaluated.
Results: Betaherpesviruses infection was effectively detected using multiplex qPCR. Six (22%) HHV-6, one (3%) HCMV and two (7%) dual infections (one with HHV-7/HHV-6, and the other with HHV-7/ HCMV). Interestingly, HHV-7 was only detected in the presence of other betaherpesviruses. Sequencing information confirmed betaherpesviruses infection. High hepatic enzyme levels and INR values>1.5 were determined in all betaherpesvirus-positive patients.
Conclusions: Multiplex qPCR facilitated efficient quantification, indicating that differentiation between betaherpesviruses is possible with the sole use of real-time PCR. Liver explant and serum samples were positive for some betaherpesviruses, and coinfection of HHV-7 with HHV-6 and HCMV was additionally detected. Based on these results, we propose that ALF patients should be screened for the presence of betaherpesviruses.
Estimating the annual risk of infection with Mycobacterium tuberculosis among adolescents in Western Kenya in preparation for TB vaccine trials
Authors: Nduba Videlis , Hoog Anna H. van’t , de Bruijn Annefleur , Mitchell Ellen M.H. , Laserson Kayla , Borgdorff Martien 
Published: August 2019

Abstract
Background: Adolescents are a prime target group for tuberculosis (TB) vaccine trials that include prevention of infection (POI). The BCG vaccine is given at birth and does not prevent TB infection. TB infection, a critical endpoint for POI vaccine trials would need to be documented to estimate sample sizes in target populations.
Methods: Adolescents aged 12-18 years of age were enrolled in an area under continuous demographic surveillance. A tuberculin skin test (TST) survey was conducted as part of a study on TB prevalence and incidence. All adolescents got TSTs at enrolment and returned after 72 hours for reading. A TST of ≥10mm if HIV negative or ≥ 5mm if HIV positive, was considered positive.
Results: Of 4808 adolescents returning for TST readings (96% of those enrolled), mean age was 14.4 (SD 1.9), 4518(94%) were enrolled in school and 21(0.4%) gave a previous history of tuberculosis. Among adolescents with TST reactivity, the mean TST induration was 13.2 mm (SD 5.4). The overall prevalence of latent TB infection was 1544/4808 (32.1%, 95% CI 29.2-35.1) with a corresponding annual risk of TB infection (ARTI) of 2.6% (95% CI 2.2-3.1). Risk factors for a positive TST included being male (OR 1.3, 95%CI 1.2,1.5), history of having a household TB contact (OR 1.5, 95%CI 1.2,1.8), having a BCG scar (OR 1.5,95%CI 1.2,1.8), living in a rural area (OR 1.4, 95%CI 1.1,1.9), and being out of school (OR 1.8, 95%CI 1.4,2.3).
Conclusion: We conclude that the high TB transmission rates we found in this study, suggest that adolescents in this region may be an appropriate target group for TB vaccine trials including TB vaccine trials aiming to prevent infection.
Therapeutic effect of vasoactive intestinal peptide on form-deprived amblyopic kittens
Authors: Li Bo , Zou Yunchun , Li Liwen , Deng Hongwei , Mi Wei , Wang Xing , Yin Ximin 
Published: August 2019

Abstract
Background: Exploring the role of vasoactive intestinal peptide (VIP) in the lateral geniculate body (LGBd) in visual development and studying the therapeutic effect of VIP on amblyopic kittens.
Methods: Three-week-old domestic cats were divided into a control group (n = 10) and a monocular deprivation group (n = 20), with an eye mask covering the right eye of those in the deprived group. After pattern visual evoked potential (PVEP) recording confirmed the formation of monocular amblyopia, the left LGBd was isolated from 5 kittens in each group. The remaining control kittens continued to be raised, and the remaining deprivation group was divided into a VIP intervention group (n = 5), Sefsol (caprylic acid monoglyceride, VIP solution) intervention group (n = 5) and amblyopia non-intervention group (n = 5) after removal of the eye mask. Three weeks later, PVEPs, VIP immunohistochemistry and VIP mRNA expression in the left LGBd were compared across groups.
Results: At 6 weeks of age, there were significant differences in P100 wave latency and amplitude and VIP immunohistochemistry and in situ hybridization between the control group and the deprivation group (P < 0.05). After 3 weeks of the corresponding interventions, the latency and amplitude in the VIP intervention group were better than that in the Sefsol intervention group and amblyopia non-intervention group (P < 0.05). Furthermore, VIP treatment increased the number of immunohistochemical VIP-positive cells (P < 0.05) and the average optical density of positive cells (P > 0.05), as well as the number (P < 0.05) and average optical density of VIP mRNA-positive cells (P < 0.05).
Conclusions: VIP plays an important role in visual development. Nasal administration of VIP can improve the function of neurons in the LGBd of kittens and has a certain therapeutic effect on amblyopia.
COMMUNICATIVE COMPETENCE BASED ENGLISH SYLLABUS DESIGN FOR STUDENTS OF PTKI (Perguruan Tinggi Keagamaan Islam)
Authors: Rosyida Ulva Fatiya 
Published: August 2019

<p align="center"><strong>ABSTRACT</strong></p><p>Communicative Competence (CC) is the target of language teaching today. It contains six competences: Linguistic Competence, Discourse Competence, Socio-Cultural Competence, Formulaic Competence, Interactional Competence, and Strategic Competence. Teaching English for students of PTKI should also convey those competences. The competences should be applied in the syllabus, the materials, etc. However, most of the English syllabus has not conveyed the highlight of those competences. This paper, therefore, aims to propose a syllabus design and the sample of materials based on Communicative Competence. The syllabus contains the highlight of those competences for each topic. The design, then, can be developed by the lecturers to meet the students’ needs.</p><p> </p><p> </p>
Comparative effectiveness of first-line nab-paclitaxel versus paclitaxel monotherapy in triple-negative breast cancer
Authors: Luhn Patricia , Chui Stephen Y , Hsieh “Angela” Fu-Chi , Yi Jingbo , Mecke Almut , Bajaj Preeti S , Hasnain Waseem , Falgas Adeline , Ton Thanh GN , Kurian Allison W 
Published: August 2019

Aim:
This observational study evaluated the effectiveness of nab-paclitaxel versus paclitaxel monotherapy as first-line (1L) treatment for metastatic triple-negative breast cancer (mTNBC).
Materials & methods:
200 patients from the US Flatiron Health electronic health record-derived database (mTNBC diagnosis, January 2011–October 2016) who received 1L nab-paclitaxel (n = 105) or paclitaxel (n = 95) monotherapy were included. Overall survival and time to next treatment were evaluated.
Results:
The adjusted overall survival hazard ratio was 0.98 (95% CI: 0.67–1.44), indicating a similar risk of death between groups. Adjusted time to next treatment hazard ratio was 0.89 (95% confidence interval: 0.62–1.29).
Conclusion:
Nab-paclitaxel and paclitaxel monotherapy showed similar efficacy, suggesting their interchangeability as 1L treatments for mTNBC.
Proposições artísticas e jogos similares
Authors: Myczkowski Rafael Schultz 
Published: August 2019

Este trabalho Proposições artísticas e jogos similares resulta da disciplina Sobre Ser Artista Professor ministrada pela Professora Dra. Jociele Lampert no Programa de Pós-Graduação em Artes Visuais da Universidade do Estado de Santa Catarina – UDESC/CEART, Florianópolis/SC.
An Analysis of Jargon Used by Receptionists in Front Office at Asa Bali Luxury Villas and Spa Seminyak
Authors: Yudha I Putu Citra , Seken I Ketut 
Published: August 2019

Penelitian ini bertujuan untuk mengidentifikasi dan mendeskripsikan bentuk linguistik, arti dan fungsi jargon yang digunakan oleh resepsionis pada front office di Asa Bali Luxury Villa and Spa
Seminyak. Jargon dianalisis dengan menggunakan teori dari Allan &Buridge (2006). Penelitian ini di desain menggunakan
metode penelitian kualitatif. Jargon yang di identifikasi adalah jargon yang digunakan dalam bentuk lisan dan tertulis. Tehknik - tehknik yang digunakan dalam mengumpulkan data adalah observasi, dokumentasi dan interview. Dalam hasil penelitian, ditemukan 123 jargon yang
digunakan oleh resepsionis di front office Asa Bali Villa and Spa. Arti dari jargon -jargon yang digunakan didefinisikan berdasaran
interview pada staff villa, dokumen resepsionis, kamus, dan konteks penggunaan jargon. Data analisis menunjukan terdapat dua fungsi jargon.
TRANSLATION CLASSROOM MANAGEMENT THROUGH PEER ASSESSMENT AND INTERNET BROWSING
Authors: I Gst Agung Sri Rwa Jayantini , I Komang Sulatra , Putu Chrisma Dewi 
Published: August 2019

This paper tries to describe the modification of peer assessment and internet browsing as a learning model in translation classroom. It includes the procedures applied in the classroom so that the lecturers in translation class can adopt the model and offer a comprehensive learning situation through the use of peer assessment and internet. The modification is a classroom management strategy to be used in delivering translation course for the English department students. The proposed learning model is encouraged by the benefits of peer assessment (Spiller, 2012). and the use of internet in the practice of translating. Here, the modification is expected to create an entirely different atmosphere in translation course. The three key points in this paper are classroom management strategy (Brophy in Korpershoek et al., 2014) peer assessment and internet browsing. Peer assessment is combined with internet browsing as the implementation of classroom management strategy with the purpose of providing the English department students an innovative learning model when they join translation course. By innovative, it means that translation course offered to English Department students is not merely centered on the lecturer’s assessment but on peer assessment, which is modified with internet browsing.
KINESICS INTERACTION: TOWARDS EYE CONTACT, POSTURE AND FACIAL EXPRESSION OF EDWARD AND BELLA IN A MOVIE ENTITLED “TWILIGHT”
Authors: Made Chintya Maha Yekti 
Published: August 2019

This study discusses the nonverbal communication particularly body language. This study focuses on kinesics such as: eye contact, posture, and facial expression of the male main character (Edward Cullen) and the female main character (Bella Swan) in Twilight movie by Stephenie Meyer. The aims of this study is to know the meaning behind those nonverbal communications of male main character and female main character as their acting in the movie. The method used to answer the problem of this study is Descriptive qualitative. The data of this study is a film entitled Twilight produced in 2008. The data is described in the form of images and words. From this study, it can be seen that there are three kinds of nonverbal communication used by the male and female main character. Those are eye contact, posture, and facial expression where the nonverbal communication used by the male character is concerned, serious, brave, romantic, cool postures, friendly and bright eyes. Whereas the female character uses dim eye contact, glace and shock posture, and amazed facial expression. It is found that there are several differences of using nonverbal communication between male and female character in the movie.
RESPON SISWA SD TERHADAP PEMBELAJARAN PENEMUAN BERBANTUAN ALAT PERAGA PADA MATERI VOLUM BALOK DAN KUBUS
Authors: Purwaningrum Jayanti Putri 
Published: August 2019

Teacher at SDN 4 Puyoh Kudus District rarely make the learning process through learning discoveries aided props on the material Volume beams and cubes. This is due, they are accustomed to using expository teaching methods which place more emphasis on the process of delivering the material verbally from teacher to student. Thus, the response of the students in the learning of the discovery needs to be examined. This study aims to investigate the response of primary school students towards learning mathematics through learning discoveries aided props. This research uses descriptive qualitative research design in which the subject of the study was nineteen students. Data collection techniques are by using questionnaires, observation sheets, documentation and interviews. The results showed that the students showed a positive response tehadap mathematics learning using discovery learning props aided by the average percentage of students who responded positively to 82.11%. In addition, the activity of students during the learning process using the learning-aided invention nice props with an average percentage of 83% of student activity.
Keywords: Response of primary school students, learning discovery, Viewer Tool
ANALISIS BUKU : BAGAIMANA KURIKULUM 2013 MEMFASILITASI BERKEMBANGNYA KETERAMPILAN MENGAMATI PADA SISWA KELAS 1,2,4 DAN 5?
Authors: Limiansih Kintan 
Published: August 2019

We analyzed the activities in the student books Curriculum 2013.This research was to understand the development of observation skills in the student book. This research was analyzed student books for grade 1, 2, 4, and 5. From the analysis, obtained information that in the student books have contained instructions or assignments for students to observe objects / events / real phenomenon that results are in keeping with the facts (appearing in grades 1, 2, 4, and 5), use a variety of senses (appearing in grade 1, 2, 4, and 5), determine similarities or differences (appearing in grades 1, 2, 4, and 5), and repeated observations to obtain accurate results (appearing in grade 1 and 4). But in the book there are no clues student or assignment for the students to use the tools of observation so the range of observation and no further details are also instructions for preparing the observation stage. In addition, the activity observed in the students' books are dominated by observing the images so that the information obtained by the students is limited.
EFEKTIVITAS PENGGUNAAN MODEL PEMBELAJARAN TALKING STICK UNTUK MENINGKATKAN KEMAMPUAN MERESPON SISWA SEKOLAH DASAR
Authors: Wulandari Ratih 
Published: August 2019

Penelitian ini dilatar belakangi oleh sulitnya siswa dalam merespon pertanyaan yang diajukan oleh guru yang berpengaruh terhadap hasil / prestasi belajar siswa. Penelitian ini bertujuan untuk memperbaiki pembelajaran IPA di SDN Cibadak 1 Kota Bandung khususnya di kelas V pada materi peredaran darah pada manusia dengan menggunakan model pembelajaran Talking stick. Penelitian Tindakan kelas ini berlangsung dalam 2 siklus.
Dari hasil dan pembahasan diperoleh beberapa kesimpulan: Pertama Hasil penelitian yang diperoleh yaitu adanya peningkatan kemampuan merespon siswa pada materi peredaran darah, pada siklus 1 terdapat 40,7% siswa yang mempunyai kemampuan merespon yang baik. Kedua Pada pelaksanaan siklus 2 merupakan perbaikan dari siklus 1 dan kemampuan merespon siswa mengalami peningkatan. menjadi 88,3 %. Selain itu juga adanya peningkatan hasil belajar siswa pada siklus 1 yang memenuhi KKM sebesar 45% dan pada siklus 2 terdapat 85,2%.
Kesimpulan dari penelitian ini adalah penggunaan model pembelajaran Talking stick dapat meningkatkan kemampuan merespon siswa pada pembelajaran IPA materi peredaran darah di kelas V SDN Cibadak 1. Dengan demikian penggunaan model pembelajaran Talking stick dapat dijadikan sebagai salah satu alternatif pendekatan pembelajaran untuk diterapkan pada pembelajaran IPA di Sekolah Dasar.
KEMAMPUAN MENULIS NARASI DIKAITKAN DENGAN SIKAP BAHASA DAN PENGETAHUAN EJAAN BAHASA INDONESIA (EBI) DI KELAS V SD NEGERI SERANG 5 KOTA SERANG
Authors: Muhyidin Asep - 
Published: August 2019

Abstract

This study aims to determine empirically the relationship of language attitudes and knowledge of Indonesian spelling (EBI) with writing narrative competence in class V SDN Serang 5 Serang City. The study was conducted on the students of class V of the odd semester of the academic year 2016/2017. The research method used in this research is survey method with correlational study approach. The population of this study is all students of class V SDN Serang 5 Serang City which amounted to 44 students. The data collection in this study is to use test instruments and questionnaires. Based on the results of research and discussion, can be drawn conclusion on the results of research as follows.

There is a positive and significant relationship between language attitudes with writing narrative competence .
There is a positive and significant relationship between knowledge of Indonesian spelling (EBI) with writing narrative competence .
There is a positive and significant relationship between language attitudes and knowledge of Indonesian spelling (EBI) together with writing narrative competence .

Keywords: Writing Narrative Competence, language attitudes,
and knowledge of Indonesian spelling (EBI)
INTERNET DAN MUSIK: MEDIA SOSIAL SEBAGAI WAHANA PUBLIKASI THE UPSTAIRS DAN DEATH FLAMES
Authors: Nur Rahmat Sujud Puji , Simatupang Lono , Albertus Harsawibawa 
Published: August 2019

Nowdays internet has become an important elemen in people life across the globe. Its impact has been seen in various scenes including music business and other artistic fields. Social media, running in support of internet, are now common in use by musicians or bands. Free of charge and global access of internet and social media provide an opportunity to disseminating the existence of a group of musicians. In this paper I would to show how social media has been utilized by a band to promote their group by themselves, focusing on myspace account of two bands, The Upstairs and death Flames. I divide this paper into introduction, an overview of www.myspace.com as well as a brief profile of the two bands, and a discussion on their account, kinds of responses and communication that established based on the accounts. Keywords: internet, musicians, band,and disseminating