bluuebunny/crossref_metadata_2025_split huggingface dataset:
A discriminator code-based DTD surveillance ensures faithful glycine delivery for protein biosynthesis in bacteria
Authors: Kuncha Santosh Kumar , Suma Katta , Pawar Komal Ishwar , Gogoi Jotin , Routh Satya Brata , Pottabathini Sambhavi , Kruparani Shobha P , Sankaranarayanan Rajan 
Published: May 2018

AbstractD-aminoacyl-tRNA deacylase (DTD) acts on achiral glycine, in addition to D-amino acids, attached to tRNA. We have recently shown that this activity enables DTD to clear non-cognate Gly-tRNAAlawith 1000-fold higher efficiency than its activity on Gly-tRNAGly, indicating tRNA-based modulation of DTD (Pawar et al., 2017). Here, we show that tRNA’s discriminator base predominantly accounts for this activity difference and is the key to selection by DTD. Accordingly, the uracil discriminator base, serving as a negative determinant, prevents Gly-tRNAGlymisediting by DTD and this protection is augmented by EF-Tu. Intriguingly, eukaryotic DTD has inverted discriminator base specificity and uses only G3•U70 for tRNAGly/Aladiscrimination. Moreover, DTD prevents alanine-to-glycine misincorporation in proteins rather than only recycling mischarged tRNAAla. Overall, the study reveals the unique co-evolution of DTD and discriminator base, “reciprocally” in Bacteria and Eukarya, and suggests DTD’s strong selection pressure on bacterial tRNAGlys to retain a pyrimidine discriminator code.
Classes of ITD predict outcomes in patients with AML treated withFLT3inhibitors
Authors: Schwartz Gregory W. , Manning Bryan , Zhou Yeqiao , Velu Priya , Bigdeli Ashkan , Astles Rachel , Lehman Anne W. , Morrissette Jennifer J.D. , Perl Alexander E. , Carroll Martin , Faryabi Robert B. 
Published: May 2018

AbstractRecurrent internal tandem duplication (ITD) mutations are observed in various cancers including acute myeloid leukemia (AML). ITD mutations of Fms-like tyrosine kinase 3 (FLT3) receptor increase kinase activity, and are associated with poor prognostic outcomes. Currently, several small-moleculeFLT3inhibitors (FLT3i) are in clinical trials for targeted therapy of high-risk FLT3-ITD-positive AML. However, the variability of survival following FLT3i treatment suggests that the mere presence ofFLT3-ITD mutations in a patient might not guarantee effective clinical response to targeted inhibition ofFLT3kinase. Motivated by the heterogeneity ofFLT3-ITD mutations, we sought to investigate the effects ofFLT3-ITD structural features on response to treatment in AML patients. To this end, we developed HeatITup (HEAT diffusion for Internal Tandem dUPlication), an algorithm to efficiently and accurately identify ITDs and classify them based on their nucleotide composition into newly defined categories of “typical” or “atypical”. Typical ITDs insert sequences are entirely endogenous to theFLT3locus whereas atypical ITDs contain nucleotides exogenous to the wildtypeFLT3. We applied HeatITup to our cohort ofde novoand relapsed AML patients. Individuals with AML carrying typical ITDs benefited significantly more from FLT3i than patients with atypical ITDs, regardless of whether FLT3i was used after initial induction or at relapse. Furthermore, analysis of the TCGA AML cohort demonstrated improved survival for patients with typical ITDs treated with induction chemotherapy. These results underscore the importance of structural discernment of complex somatic mutations such as ITDs in progressing towards personalized treatment for AML patients.
Gender wage gap in selected developing upper-middle income countries
Authors: Almasifard Maryam 
Published: May 2018

Purpose
The purpose of this paper is to examine the relationship between gender wage gap, productivity level of labor force and international trade for a sample of 13 developing upper-middle income countries over the period 2001 to 2015.

Design/methodology/approach
According to different statistical tests such as F-Limer test, the proper method for estimating this model is panel regression analysis. The Hausman test was handled to realize the fixed or random effect characteristics of this data. The final result of this test shows that the data follow some kind of random behavior which makes the panel regression model, random effect a suitable method for estimating this data.

Findings
The regression results showed that women’s (and men’s) employment in this sample has a positive relationship with their wages. Results showed that labor force’s productivity level affects their wage, and therefore, productivity difference between women and men is impressive on the gender wage gap. The significant finding is about international trade. While international trade has a positive effect on the wage rate of both genders, this effect is stronger for the female labor force. As a result of a stronger effect of international trade on the female labor force, a negative effect of international trade on the gender wage gap is observed.

Research limitations/implications
Productivity variables are not available for this sample countries, so the author creates a new variable which is going to be used as a proxy for productivity. The author divides value added in each section (Agriculture, Manufacture, Industry, Service) by the total number of employees in that section; then for calculating the productivity rate of women, the author multiplies the result by the percentage of the employed women in that sector; for the productivity of men in that sector, the author multiplies the result by the percentage of men employed in that sector.

Originality/value
This paper contributes to the available studies by selecting a new sample of developing countries with upper-middle income level and also by introducing a new variable which is useful for measuring labor force productivity level.
Shared leadership in entrepreneurial teams: the impact of personality
Authors: Hensel Rainer , Visser Ronald 
Published: May 2018

Purpose
The purpose of this paper is to develop a model to better understand which personality traits and personal values impact transformational leadership qualities in self-directed entrepreneurial teams as perceived by team members.

Design/methodology/approach
A cohort consisting of six self-directed entrepreneurial teams was selected. A multi-rater system was applied to assess the perceived transformational leadership qualities. A model was developed, using three dimensions of transformational leadership as dependent variables: inspiring others, stimulating interaction among group members and communicating a strong vision.

Findings
The ability to inspire others was predicted by friendliness, measuring a positive labeling of social phenomena. In addition, two positive moderation effects emerged as being related to inspirational capacities: assertiveness and despondency, and assertiveness and emotional empathy interacted. The second moderation effect also impacted the capacity to stimulate group interaction. The personality traits “modesty” and the personal value “human relations” were negatively related to the perceived capacity to communicate a strong vision. Furthermore, a significant but moderate effect of team membership on the capacity to inspire others respectively stimulate interaction seems to exist.

Practical implications
The research results offer valuable opportunities to enhance or to develop those informal, transformational leadership qualities positively influencing entrepreneurial effectiveness.

Social implications
As entrepreneurship in small, self-directed teams is a popular phenomenon, research results add to the understanding of group interaction related to informal leadership.

Originality/value
Shared or informal transformational leadership in the context of self-directed, entrepreneurial teams is a relatively new phenomenon. Integrating a multi-rater assessment of leadership with personality combines interesting perspectives.
Entrepreneurial activities in a developing country: an institutional theory perspective
Authors: Eijdenberg Emiel L. , Thompson Neil A. , Verduijn Karen , Essers Caroline 
Published: May 2018

PurposeEntrepreneurship research in the context of developing countries has typically investigated the ways in which culture, politics or economic institutions prohibit or enable entrepreneurial activities using macro-level surveys and deductive designs. In contrast, the purpose of this paper is to take a micro-institutional perspective to study these three institutions influencing entrepreneurial activities in such a context.Design/methodology/approachThe analysis is based on inductive, qualitative field data from a challenging institutional environment, Tanzania. This includes two focus groups, one with experts and one with entrepreneurs; and 24 individual interviews with entrepreneurs.FindingsEntrepreneurial activities in Tanzania are not constrained only by bureaucracy and arbitrary enforcement, access to capital, competition and consumer spending, but also by language barriers, negative media portrayals and gender disparity. In their favour, recent trade policy, opening up of borders and changing gender relations, has led to more opportunities, but just as important are traditional festivals, marital gift-giving and familial support. Entrepreneurs respond to institutional constraints in many creative ways, including undertaking entrepreneurial strategies, developing inner strength, joining associations, giving back to communities and skilfully managing relations with authorities.Originality/valueThe fine-grained discussion of the findings of this study specifically contributes to theory by illustrating the constraining and enabling role of under-represented institutions, such as festivals and marriages, as well as entrepreneurial creative responses that define everyday entrepreneurial life in a developing country.
Customer value in self-service kiosks: a systematic literature review
Authors: Vakulenko Yulia , Hellström Daniel , Oghazi Pejvak 
Published: May 2018

Purpose
The purpose of this paper is to provide a cohesive overview of the available self-service and customer value literature, identify customer value in self-service kiosks (SSKs), and analyze this value from the customer experience perspective.

Design/methodology/approach
The study comprises a systematic literature review of available works on customer value.

Findings
The paper presents conclusions on the SSK’s technological forms, presence in industries, and conceptual state. The review also provides a cohesive inventory of customer value elements in SSKs. The in-depth analysis proposes two alternative models of the customer value creation process: linear and circular.

Research limitations/implications
The study reveals gaps stemming from the inconsistency and fragmented nature of previous research on customer value in SSKs. The gaps are treated as opportunities for future studies.

Practical implications
By identifying new sources of competitive advantage and new ways to improve customer service strategies and experience management, the findings support managerial decision making at the stages of considering, implementing, and improving SSK networks.

Originality/value
This study is the first to systematically review and provide an inventory of customer value elements in SSKs. It, therefore, offers new perspectives on customer value creation using self-service technology.
Absorption, combination and desorption: knowledge-oriented boundary spanning capacities
Authors: Denford James Stephen , Ferriss Allan 
Published: May 2018

PurposeThe purpose of this paper is to theoretically develop and empirically explore knowledge absorption, combination and desorption within and between organizations.Design/methodology/approachOn the basis of knowledge-based view and absorptive capacity, the authors have conducted a multiple-case study to develop a theoretically grounded and empirically supported model of intra- and inter-firm knowledge cycles.FindingsFirms identify their knowledge gaps and stocks, both tacit and explicit, undertaking efforts to fill the latter and maximize the value of the former. The paper finds that knowledge exploration, integration and exploitation both within the firm and between firms relies on absorptive, combinative and desorptive capacities. Further, as such capacities are organizationally expensive to maintain, firms will often emphasize one capacity over the other and focus either internally or externally to meet organizational goals.Originality/valueWhile there is extensive research into absorptive capacity and some into combinative capacity, there is little empirical investigation of desorptive capacity and none into the integration of the three concepts; this paper seeks to fill that gap. Moreover, the resulting novel integrative model allows managers and researchers to identify the various capacities in use and their applications within the firm and between firms.
Have the gasb no. 34 infrastructure reporting requirements affected state highway spending?
Authors: Kim Jiseul , Ebdon Carol 
Published: May 2018

AbstractGASB Statement No. 34 required state and local governments to report information regarding general infrastructure in financial statements, to improve understanding of the organization's investments in capital assets. Some proponents suggested that this information would affect management practices and potentially resource allocation decisions, but initial survey data found limited evidence of effects. We use dynamic panel analysis covering 47 states from 1995 to 2009 to explore whether implementation of GASB 34 affected state highway capital and maintenance spending. We find evidence of increased capital spending, but no statistically significant change in maintenance expenditures. The choice of reporting method was not found to affect spending outcomes.
Raising local revenue: The use and adequacy of voluntary property taxes in arkansas
Authors: Hoffman Kim U. , Howard Joseph Yuichi 
Published: May 2018

AbstractWith the late-2000s recession, state and local governments have struggled to find the necessary revenue to sustain citizens' demands of governmental services. One potential revenue source is to allow the citizens' themselves to choose the services to fund through the usage of voluntary taxes. Counties and cities in Arkansas have the authority to levy a voluntary property tax to support specific public services. In this study, we explore the prevalence and adequacy of the voluntary property tax by local governments in Arkansas. We identify 58 different voluntary taxes used in 27 counties and 17 cities throughout the state. Moreover, using revenue and expenditure data, we find the tax to be a significant revenue source for several county programs.
Quality in museums and libraries: a comparison of indicators
Authors: Poll Roswitha 
Published: May 2018

Purpose
The purpose of this paper is to define quality criteria for museum work and try to identify indicators for assessing such quality, using the well-known quality indicators for libraries as basis of comparison.

Design/methodology/approach
In 2016, the first international standard for museum statistics was published (ISO 18461). At the same time, the museum community realized the need to proceed from statistics to quality assessment in order to prove the effectiveness and efficiency of museum performance and finally also the influence of museums on society. The paper analyses the existing literature on museum quality and museum evaluation and compares the findings to the established methods in the library sector.

Findings
Comparison of quality criteria and quality evaluation in museums and libraries shows not only many similarities in what is regarded as quality, but also considerable differences in the options for assessment.

Research limitations/implications
The paper shows a tentative selection of potential quality indicators and quality assessment methods for museums. Further work and practical expertise will be needed for developing and testing a reliable set of methods. The new ISO project 21246 key indicators for museums will further this development.

Practical implications
There is an evident similarity in the mission and goals of cultural institutions such as archives, libraries and museums. Methods already in use in libraries for assessing performance quality and library impact can therefore also be useful in the museum sector. But the immense variety of museums requires an adaptation of existing methods and a number of new indicators especially devised for museum tasks.

Originality/value
The paper describes possible solutions for evaluating the quality of museums. As quality criteria are similar in museums and libraries, new quality indicators for museums may in turn become useful in the library sector.
Effects of solder paste on thermal and optical performance of high-power ThinGaN white LED
Authors: Raypah Muna E. , Devarajan Mutharasu , Sulaiman Fauziah 
Published: May 2018

Purpose
Thermal management of high-power (HP) light-emitting diodes (LEDs) is an essential issue. Junction temperature (TJ) and thermal resistance (Rth) are critical parameters in evaluating LEDs thermal management and reliability. The purpose of this paper is to study thermal and optical characteristics of ThinGaN (UX:3) white LED mounted on SinkPAD by three types of solder paste (SP): No-Clean SAC305 (SP1), Water-Washable SAC305 (SP2) and No-Clean Sn42/Bi57.6/Ag0.4 (SP3).

Design/methodology/approach
Thermal transient tester (T3Ster) machine is used to determine TJ and total thermal resistance (Rth–JA). In addition, the LED’s optical properties are measured via thermal and radiometric characterization of power LEDs (TeraLED) system. The LED is mounted on SinkPAD using SP1, SP2 and SP3 by stencil printing to control a thickness of SP and reflow soldering oven to minimize the number of voids. The LED with SP1, SP2 and SP3 is tested at various input currents and ambient temperatures.

Findings
The results indicate that at high input current, which equals to 1,200 mA, Rth–JA and TJ, respectively, are reduced by 30 and 17 per cent between SP1 and SP2. At same current value, Rth–JA and TJ are minimized by 42 and 25 per cent between SP1 and SP3, respectively. In addition, at an ambient temperature of 85°C, Rth–JA and TJ are decreased by 34 and 7 per cent between SP1 and SP2, respectively. Similarly, the reduction in Rth–JA and TJ between SP1 and SP3 is 44 and 10 per cent, respectively. Luminous flux, luminous efficacy and color shift of the LED with the three types of SPs are compared and discussed. It is found that the SP1 improves the chromatic properties of the LED by increasing the overall light efficiency and decreasing the color shift.

Originality/value
Thermal and optical performance of ThinGaN LEDs mounted on SinkPAD via three types of SPs is compared. This investigation can assist the research on thermal management of HP ThinGaN-based LEDs.
Managing tourism knowledge: a review
Authors: Cooper Chris 
Published: May 2018

PurposeThis paper aims to provide a contemporary review of the field of tourism and knowledge management.Design/methodology/approachThe review draws upon an extensive range of generic knowledge management literature as well as the rather less developed literature on tourism and knowledge management.FindingsThe review finds that tourism has been slow to adopt a knowledge management approach, partly due to the context of the tourism sector. However, by taking a “network gaze”, this paper shows that the benefits of knowledge management for tourism are clear and that policy for knowledge management can be of benefit to tourism.Originality/valueThis paper provides a contemporary review of the knowledge management literature and situates it within the tourism context.
Measuring and improving food safety culture in a five-star hotel: a case study
Authors: Caccamo Aurelia , Taylor Joanne Zaida , Daniel Dellora , Bulatovic-Schumer Ringaile 
Published: May 2018

Purpose
The purpose of this paper is to present a case study of the JW Marriott Marquis in Dubai, the tallest hotel in the world, which measured and improved their food safety culture as part of the Culture Excellence Program. It is the fifth article in a theme issue of Worldwide Hospitality and Tourism Themes, discussing the importance of measuring food safety and quality culture.

Design/methodology/approach
A longitudinal case study was used, including an online anonymous survey taken by a representative number of employees and supporting in-depth semi-structured interviews.

Findings
The company received a high score in year one of the research, and the reasons for this are discussed. Taking their best practices further with the use of the survey data, they then saw quantitative improvement in year two which was maintained in year three. This demonstrates elements of best practice in food safety management and how measuring culture within a business can facilitate continual improvement.

Originality/value
This paper demonstrates how and why a five-star hotel has measured and improved their food safety culture, with practical examples. It will be of value to food safety and quality practitioners, trainers, auditors and other stakeholders involved in the food industry.
Measuring and improving food safety culture in a large catering company: a case study
Authors: Nouaimeh Nancy , Pazhanthotta Raseena T. , Taylor Joanne Zaida , Bulatovic-Schumer Ringaile 
Published: May 2018

Purpose
The purpose of this paper is to present a case study of a large catering company in the United Arab Emirates, which measured and improved its food safety culture as part of the Culture Excellence Program. It is the sixth article in a theme issue of Worldwide Hospitality and Tourism Themes, discussing the importance of measuring food safety and quality culture.

Design/methodology/approach
A longitudinal case study was used, including an online anonymous survey taken by a representative number of employees and supporting in-depth semi-structured interviews.

Findings
The company received a high score in year one of the research, and the reasons for this are discussed. Taking their best practices further with the use of the survey data, they then saw quantitative improvement in year two. This demonstrates elements of best practice in food safety management and how measuring culture within a business can facilitate continual improvement.

Originality/value
The paper demonstrates how and why a large-scale catering company has measured and improved their food safety culture, with practical examples. It will be of value to food safety and quality practitioners, trainers, auditors and other stakeholders involved in the food industry.
Making the ‘Invisible’ Visible: Redevelopment‐induced Displacement of Migrants in Shenzhen, China
Authors: Liu Ying , Geertman Stan , van Oort Frank , Lin Yanliu 
Published: May 2018

AbstractGentrification in China is intertwined with urban redevelopment, which causes the large‐scale displacement of rural–urban migrants from ‘villages in the city’ (ViCs). Because of the informality of ViCs, migrant renters have very insecure tenancy and during redevelopment they are treated as a negligible (‘invisible’) social group. As they are very difficult to locate after displacement, they are also literally invisible to researchers. To make the invisible visible, this study traced a sample of displaced migrants from Huangbeiling village in Shenzhen. The focus was on the displacement process and on identifying the consequences for the displaced. We found various forms of displacement during the redevelopment process. Nearby ViCs were prioritized by displaced migrants to minimize as much utility loss as possible. However, they generally suffer from decreased proximity, increased living costs, and the loss of social networks and job opportunities. Remarkably, some choose to return to the gentrifying village, enduring displacement in situ caused by increasing rents, drastic physical neighbourhood changes and declining liveability, in exchange for retaining their original social and economic networks. Large‐scale urban redevelopment is causing the rapid shrinkage of informal housing. Recognizing and addressing the housing needs of this impoverished social group is a matter of urgency.