bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of posture and muscle stiffness between adolescent boys with haemophilia and age-matched healthy peers: An observational comparative study
Authors: Deniz Volkan , Güzel Nevin Atalay , Kelle Bayram , Antmen Ali Bülent 
Published: December 2024

BACKGROUND:
Haemophilic arthropathy is likely to influence posture and muscle stiffness in adolescent male haemophilia patients (HP).

OBJECTIVE:
This study aimed to investigate the possible change in upright standing posture and stiffness of the superficial postural muscles in HP.

METHODS:
Twenty-two HP aged between 12 and 19 years and twenty-two healthy peers were included in the study. The photogrammetry was used to assess the upright standing posture from sagittal and frontal planes. Also, stiffness of the superficial postural muscles was evaluated using the myotonometry.

RESULTS:
A significant difference was found in the craniovertebral, lumbar lordosis, knee flexion-valgus, and ankle plantar flexion angles between the groups ([Formula: see text] 0.05). Craniovertebral, knee flexion, and knee valgus angles were lower; whereas lumbar lordosis and ankle plantar flexion angles were higher in HP compared to the healthy peers. Stiffness of the rectus femoris muscle was lower in HP ([Formula: see text] 0.001).

CONCLUSION:
This study revealed that the ankle, knee, lumbar, and craniovertebral segments’ posture angles were changed and the stiffness of the rectus femoris muscle decreased in HP. Postural alterations and reduced rectus femoris stiffness should be considered in management of the musculoskeletal complications of haemophilia.
Edukasi Petugas Puskesmas dan Hubungannya dengan Oral Hygiene Siswa Sekolah Dasar di Sinjai, Sulawesi Selatan
Authors: Abdullah Nurwiyana , Asridiana  , Nur Aida Wanda , Supriatna Agus , Arif Anugrah 
Published: December 2024

Prevalensi penyakit gigi dan mulut diindonesia masih tinggi terutama pada usia 6-12 tahun. Hasil Riset Kesehatan Dasar indonesia pada tahun 2018 menunjukan bahwa prevalensi masalah gigi dan mulut sebesar 57,6% dan yang mendapat pelayanan dari tenaga medis gigi sebesar 10,2% (Riskesda, 2018), untuk mengatasi hal tersebut petugas puskesmas memiliki kewenangan bertugas untuk melayani masyarakat dalam penanganan masalah kesehatan gigi dan mulut. Penelitian ini bertujuan untuk mengetahui hubungan kunjungan dan edukasi oleh petugas puskesmas dengan Oral Hygiene Siswa SDN 92 Panaikang, Kec. Sinjai Timur Kabupaten Sinjai. Penetian ini merupakan penelitian kuantitatif. Sampel yang digunakan sebanyak 78 orang siswa SD kelas 4,5,6. Pengambilan data dilakukan dengan pemeriksaan langsung kesehatan gigi dan mulut siswa dan menentukan nilai OHI-Snya serta pemberian kuisioner mengenai pengetahuan siswa terkait masalah kebersihan gigi dan mulut. Analisis data menggunakan Chi-square untuk melihat hubungan kunjungan dan edukasi petugas puskesmas dengan kebersihan gigi dan mulut siswa. Hasil penelitian menunjukkan bahwa terdapat peningkatan pengetahuan serta nilai OHI-S siswa setelah dilakukan kunjungan dan edukasi oleh petugas puskesmas. Hasil uji chi-square menunjukkan terdapat hubungan yang signifikan antara tingkat pengetahuan siswa dan nilai OHIS-nya (P=0.000). Dapat disimpulkan bahwa terdapat hubungan kunjungan dan edukasi oleh petugas puskesms dengan oral hygiene Siswa SDN 92 Panaikang, Kec. Sinjai Timur Kabupaten sinjai.
Penyuluhan Kesehatan Gigi dan Mulut: Efektivitas Media Booklet, Flipchart, dan Video Animasi dalam Meningkatkan Pengetahuan
Authors: Nur Aida Wanda , Liasari Ira , Mirawati Hamid Ellis 
Published: December 2024

Masalah Kesehatan gigi dan mulut di Indonesia mengalami peningkatan berdasarkan hasil riskesdas pada tahun 2007 sebanyak 43,4% menjadi 53,3% pada tahun 2013 dan sebesar 57,6 % pada tahun 2018. Prevalensi karies di Sulawesi Selatan 55,54 %, di Kota Makassar sebanyak 52,09%, serta pada kelompok umur 5-9 tahun sebanyak 65,51%. Sumber masalah kesehatan gigi umumnya berkaitan erat dengan perilaku pemeliharan kebersihan gigi dan mulut. Untuk merubah perilaku yang buruk, salah satunya dengan melakukan intervensi melalui pendidikan. Tujuan penelitian ini untuk mengetahui efektivitas penyuluhan kesehatan gigi dan mulut menggunakan media booklet, flipchart, dan video animasi terhadap peningkatan pengetahuan kesehatan gigi dan mulut anak. Jenis penelitian ini dengan design penelitian pre-post test dengan memberikan tiga kelompok intervensi yang berbeda. Analisa data menggunakan Uji Berpasangan Friedman karena data terdistribusi normal. Hasil penelitian nilai p value m kelompok intervensi media booklet dan video animasi 0,000 (p<0,05) yang artinya media booklet dan video animasi efektif dalam meningkatkan pengetahuan kesehatan gigi dan mulut sedangkan nilai p value kelompok intervensi flipchart 0,115 (p>0,05) artinya media flipchart tidak efektif dalam meningkatkan pengetahuan kesehatan gigi dan mulut.
TINJAUAN NORMATIF TENTANG PENEGAKAN HUKUM TERHADAP PELAKU TINDAK PIDANA PERDAGANGAN SATWA LIAR MENURUT UNDANG-UNDANG NOMOR 5 TAHUN 1990 (Studi Kasus Di Indragiri Hilir)
Authors: Adi Putra Bambang Sasmita , Fitri Wahyuni  
Published: December 2024

Indonesia is one of the most biodiverse countries in the world, with a wide variety of wildlife living in a variety of habitats, from tropical rainforests to oceans. Iconic wildlife includes iconic wildlife such as the Sumatran Tiger, Orangutan, Javan Rhino, Komodo dragon, and bird of paradise. However, this diversity is threatened by human activities such as poaching, illegal trade, deforestation and habitat destruction. To protect this biodiversity, law enforcement is needed against perpetrators of wildlife trade crimes,

which are regulated in Law Number 5 of 1990. This research aims to provide an in-depth understanding of the dynamics of law enforcement for perpetrators of wildlife trade crimes and encourage improvements in existing legal practices. This research uses the normative legal research method, this research focuses on analyzing legal documents and sources. This method involves the study of various legal sources, such as laws, court decisions, contracts, legal theories, and experts' views. The results of this study show that the police have been quite good at investigating and arresting perpetrators, as well as continuing the legal process in accordance with Law No. 5 of 1990. The forest rangers are responsible for forest monitoring and community education on wildlife conservation, while the BKSDA identifies the condition of confiscated animals and is involved in conservation and education efforts..
PELAKSANAAN PROGRAM DESA MAJU INHIL JAYA (DMIJ) PLUS TERINTEGRASI GUNA PERCEPATAN PEMBANGUNAN DI KABUPATEN INDRAGIRI HILIR
Authors: Syarifudin  , Jamri  
Published: December 2024

Dalam rangka implentasi Undang-Undang Nomor 6 Tahun 2014 tentang Desa tersebut pemerintah Kabupaten Indragiri Hilir membuat suatu program yanag di beri nama Desa Maju Inhil Jaya. Program Desa Maju inhil Jaya adalah suatu program dimana desa diberi otonomi yang luas dalam pelaksanan pembangunan desa dengan prinsip-prinsip desentralisasi, keterpaduan, musyawarah, kemandirian, partisipasi, kesetaraan dan keadilan gender, akuntabel dan transfaran,efektif dan efisien, dan berkelanjutan sebagaimana yang dijelaskan dalam Peraturan Daerah Kabupaten Indragiri Hilir No 7 Tahun 2021 tentang Program Desa Maju Inhil Jaya (DMIJ) Plus Terintegrasi.
Permasalahan sarana dan prasarana infrastruktur transportasi seperti jalan memang menjadi faktor penghambat dalam percepatan pembangunan dihampir setiap desa yang ada di Kabupaten Indragiri Hilir. Dengan kondisi jalan yang rusak, mustahil warga di desa bisa dengan leluasa menjalankan perekonomiannya.
Dalam penjelesan diatas tentunya program Desa Maju Inhil Jaya (DMIJ) Plus Terintegrasi dapat memberikan dampak yang positif terhadap proses pembangunan yang terjadi di desa-desa yang ada di Kabupaten Indragiri Hilir.
Penerapan Aplikasi Berbasis Mobile untuk Memudahkan Pemesanan Online Usaha Mikro Kecil Menengah (UMKM)
Authors: Tofani Ego Umarella , Marsel Marsel , Kurniawan Deni , Nurwahid Nurwahid , Zuraidah Eva 
Published: December 2024

Abstrak – Penelitian ini berfokus pada penerapan aplikasi berbasis mobile dalam memudahkan pemesanan online untuk Usaha Mikro, Kecil, dan Menengah (UMKM). UMKM memiliki peran strategis dalam perekonomian Indonesia, namun menghadapi tantangan persaingan bisnis yang semakin ketat dan tuntutan transformasi digital. Masalah utama yang diidentifikasi adalah kurangnya integrasi antara platform penjualan dan saluran pemasaran digital, sehingga menyulitkan pelanggan dalam melakukan pemesanan dan pembayaran secara mudah dan aman. Solusi yang ditawarkan dalam penelitian ini adalah aplikasi mobile yang dirancang dengan antarmuka pengguna yang intuitif dan ramah pengguna, serta mengintegrasikan sistem pembayaran. Aplikasi akan dirancang menggunakan framework Flutter dan bahasa pemrograman Dart dengan menerapkan model Rapid Application Development (RAD) untuk memperoleh hasil yang lebih cepat dan optimal. Hasil dari penelitian ini menunjukkan bahwa dengan memanfaatkan keunggulan aplikasi mobile yang mudah diakses, user-friendly, dan terjangkau, aplikasi ini dapat membantu UMKM melakukan transaksi bisnis secara lebih efisien. Penelitian ini bertujuan merancang dan mengembangkan aplikasi mobile yang terintegrasi, mengidentifikasi faktor-faktor yang memengaruhi penerapannya, serta memberikan rekomendasi untuk optimalisasi aplikasi sesuai kebutuhan pengguna UMKM.Kata kunci: Aplikasi Pemesanan Online , Usaha Mikro Kecil dan Menengah (UMKM), Flutter , Dart, RAD. Abstract – This research focuses on the application of mobile-based applications in facilitating online ordering for Micro, Small and Medium Enterprises (MSMEs). MSMEs have a strategic role in the Indonesian economy, but face the challenges of increasingly fierce business competition and the demands of digital transformation. The main problem identified is the lack of integration between sales platforms and digital marketing channels, making it difficult for customers to place orders and make payments easily and securely. The solution offered in this research is a mobile application designed with an intuitive and user-friendly user interface, as well as integrating the payment system. The application will be designed using the Flutter framework and Dart programming language by applying the Rapid Application Development (RAD) model to obtain faster and more optimal results. The results of this research show that by utilizing the advantages of mobile applications that are easily accessible, user-friendly, and affordable, this application can help MSMEs conduct business transactions more efficiently. This research aims to design and develop an integrated mobile application, identify factors that affect its implementation, and provide recommendations for optimizing the application according to the needs of MSME users.Keywords: Online Ordering Application, Micro Small and Medium Enterprises (MSMEs), Flutter, Dart, RAD.
Association between trimethylamine N-oxide and prognosis of patients with myocardial infarction: a meta-analysis
Authors: Li Xiuqing , Wang Yubao , Xu Jie , Luo Kaili , Dong Tao 
Published: December 2024

BackgroundTrimethylamine N-oxide (TMAO) has been widely explored and considered as a biomarker for adverse cardiovascular events. However, the relationships between TMAO adverse cardiovascular events are inconsistent in patients. Therefore, this meta-analysis aimed to estimate association between TMAO levels and the prognosis of patients with myocardial infarction (MI).MethodsWe searched PubMed, EMBASE, the Cochrane Library, and Web of Science from inception to July 2, 2023, to retrieve all relevant clinical trials. Associations between TMAO levels, major adverse cardiovascular events (MACE), all-cause mortality, recurrent MI, stroke, etc., were systematically addressed. Outcomes included MACE, all-cause mortality, recurrent MI, rehospitalization caused by heart failure, stroke, revascularization, SYNTAX score, and multivessel disease. A fixed/random-effects model should be adopted to calculate the pooled estimates. Besides, funnel plot, Begg's test and Egger' test were used to test publication bias.ResultsA total of nine studies were included in our meta-analysis. Our results indicated that higher TMAO levels were associated with greater risk of MACE (RR = 1.94; 95% CI = 1.39 to 2.73), all-cause mortality (RR = 1.56; 95% CI = 1.00 to 2.44), and MI (RR = 1.21; 95% CI = 1.01 to 1.45). No significant association was found in stroke, SYNTAX, and multivessel disease. Besides, our results reported that the association between TMAO levels and MACE after MI was not affected by the geographic localization.ConclusionThis study was the first meta-analysis that showed a significant positive association of TMAO levels with MACE, all-cause mortality, and recurrent MI in patients with MI.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=460400, PROSPERO (CRD42023460400).
A generalized equation for predicting peak oxygen consumption during treadmill exercise testing: mitigating the bias from total body mass scaling
Authors: Santana Everton J. , Cauwenberghs Nicholas , Celestin Bettia E. , Kuznetsova Tatiana , Gardner Christopher , Arena Ross , Kaminsky Leonard A. , Harber Matthew P. , Ashley Euan , Christle Jeffrey W. , Myers Jonathan , Haddad Francois 
Published: December 2024

BackgroundIndexing peak oxygen uptake (VO2peak) to total body mass can underestimate cardiorespiratory fitness (CRF) in women, older adults, and individuals with obesity. The primary objective of this multicenter study was to derive and validate a body size-independent scaling metric for VO2peak. This metric was termed exercise body mass (EBM).MethodIn a cohort of apparently healthy individuals from the Fitness Registry and the Importance of Exercise National Database, we derived EBM using multivariable log-normal regression analysis. Subsequently, we developed a novel workload (WL) equation based on speed (Sp), fractional grade (fGr), and heart rate reserve (HRR). The generalized equation for VO2peak can be expressed as VO2peak = Cst × EBM × WL, where Cst is a constant representing the VO2peak equivalent of one metabolic equivalent of task. This generalized equation was externally validated using the Stanford exercise testing (SET) dataset.ResultsA total of 5,618 apparently healthy individuals with a respiratory exchange ratio &gt;1.0 (57% men, mean age 44 ± 13 years) were included. The EBM was expressed as Mass (kg)0.63 × Height (m)0.53 × 1.16 (if a man) × exp (−0.39 × 10−4 × age2), which was also approximated using simple sex-specific additive equations. Unlike total body mass, EBM provided body size-independent scaling across both sexes and WL categories. The generalized VO2peak equation was expressed as 11 × EBM × [2 + Sp (in mph) × (1.06 + 5.22 × fGr) + 0.019 × HRR] and had an R2 of 0.83, p &lt; 0.001. This generalized equation mitigated bias in VO2peak estimations across age, sex, and body mass index subgroups and was validated in the SET registry, achieving an R2 of 0.84 (p &lt; 0.001).ConclusionsWe derived a generalized equation for measuring VO2peak during treadmill exercise testing using a novel body size-independent scaling metric. This approach significantly reduced biases in CRF estimates across age, sex, and body composition.
Population structure and dynamic characteristics of three endemic Chinese Abies species in southeastern Tibet, China
Authors: Huang Di , Ren Yihua , Yang Shouzhi , Zhao Yingxia , Zhao Guoqing 
Published: December 2024

IntroductionIn the face of escalating climate change, conserving fir forests in southeastern Tibet is paramount. These forests uphold Tibetan biodiversity and support crucial ecological services.MethodsThis study used the typical plot method to investigate the survival status and development trends of three Chinese endemic Abies species, namely, Abies georgei var. smithii, Abies chayuensis, and Abies delavayi var. motuoensis, from the diameter structure, static life table, and survival curve.ResultsThe results revealed that 1) the density of Abies georgei var. smithii, Abies chayuensis, and Abies delavayi var. motuoensis in the community is 408, 320, and 103 trees per hectare, respectively. The structure of the diameter class of the three species of fir trees is a pyramid shape. As the diameter class increases, the number of each population fluctuates to varying degrees, and there is a lack of many medium- and large-diameter trees. 2) The survival curve of Abies georgei var. smithii tends to be similar to the Deevey type II curves, whereas the survival curves of Abies chayuensis and Abies delavayi var. motuoensis tend to be similar to the Deevey type III curves. Various population structures are growth-oriented but highly sensitive to external random disturbances, with mortality and disappearance rates multiple times, indicating poor population development. Survival analysis reveals that all populations begin to decline after the middle age range and that the age structure is relatively unstable.DiscussionThe results of this study contribute to revealing the structural characteristics and dynamic patterns of various spruce populations, providing a theoretical basis for the management and sustainable utilization of fir forests in southeastern Tibet.
Global research hotspots and trends of theta burst stimulation from 2004 to 2023: a bibliometric analysis
Authors: Liu Mingyue , Jin Shasha , Liu Mengya , Yang Bin , Wang Qian , Fan Chunliang , Li Zhe , Wu Liang 
Published: December 2024

BackgroundTheta burst stimulation (TBS) has garnered widespread attention in the scientific community, but a comprehensive bibliometric analysis of TBS research remains absent. This study aims to fill this gap by elucidating the characteristics, hotspots, and trends in TBS publications over the past 20 years using bibliometric methods.MethodsWe retrieved TBS-related publications from January 1, 2004, to December 31, 2023, from the Web of Science Core Collection (WoSCC). The analysis focused on articles and review articles. Data were processed using the bibliometric package in R software, and CiteSpace and VOSviewer were employed for bibliometric and knowledge mapping analyses.ResultsA total of 1,206 publications were identified, with 858 included in the analysis. The annual publication volume showed a fluctuating upward trend. Leading institutions and authors were predominantly from the United States of America (USA) and European countries. Core journals and publications also primarily originated from these regions. Current research hotspots include the clinical applications and mechanisms of TBS in neurorehabilitation and depression. TBS cerebellar stimulation has emerged as a promising therapeutic target. Future research is likely to focus on dysphagia, cognitive impairments, and post-traumatic stress disorder.ConclusionThis bibliometric analysis provides an overview of the basic knowledge structure, research hotspots, and development trends in TBS research over the past two decades. The findings offer valuable insights into the evolving landscape of TBS research and its potential directions.
Effect of cue validity on the contextual cueing effect
Authors: Su Wen , Zhao Guang , Ma Jie 
Published: December 2024

PurposeIn daily life, people are adept at extracting task-relevant information from complex visual environment to guide attention more effectively toward the target. This process underpins the contextual cueing effect, where repeated exposure allows individuals to learn associations between contextual cues and targets, thereby enhancing visual search efficiency. However, the cue validity of context —how consistently cues predict target locations—is not always guaranteed in real life. This study focused on cue validity as a critical factor in understanding the contextual cueing effect. Within the study of contextual cueing, cue validity specifically refers to the probability that contextual cues accurately indicate the location of a target.MethodsIn Experiment 1, we manipulated three levels of cue validity (100, 75, and 50%) using a classic contextual cueing paradigm. Experiment 2 examined the potential impact of an imbalanced predictable vs unpredictable trial ratio. In Experiment 3, we explored whether the absence of the contextual cueing effect was due to unsuccessful learning or unsuccessful later expression.ResultsResults from Experiment 1 revealed that higher cue validity (100 and 75%) significantly elicited the contextual cueing effect, resulting in faster responses for repeated displays, whereas lower cue validity (50%) did not result in this effect because the repeated displays could not be effectively learned. Experiment 2 showed that the contextual cueing effect remained robust despite an imbalanced ratio of predictable to unpredictable displays. Experiment 3 further showed that low cue validity affects the early learning phase of context-target associations rather than the later expression in visual search.ConclusionOur study highlights the significant role of cue validity in implicit learning from visual cues. High cue validity enhances learning by providing highly stable context-target associations, while low cue validity does not actively facilitate attention allocation, thereby not promoting the learning process. These findings underscore the importance of cue validity in processing visual information.
Exploring prevention and control mechanisms of youth substance use: a case of North Wollo and Waghimra, Northeast Ethiopia
Authors: Asmare Wedi Sindew , Abate Biruk Beletew , Anmut Asres Tesfa , Abera Mohammed Aragaw , Bekele Sentayehu Oljira , Sendekie Ashenafi Kibret 
Published: December 2024

BackgroundSubstance use among youths is a significant global and local issue. Youth who engage in substance use often experience various psychosocial, health, economic, and other problems. While governmental and non-governmental organizations in North Wollo and Waghimra Zones offer social services, their effectiveness in preventing and controlling substance use remains largely unstudied. This research aims to explore youth substance use prevention techniques and control mechanisms, youth participation, and potential challenges encountered by social service organizations.MethodsA qualitative case study design was employed in North Wollo and Waghimra Zones, Northeast Ethiopia. Purposive sampling was used to recruit participants. A total of 40 participants were involved, including 10 key informant interviews and 5 focus group discussions (FGDs) of youths (6 participants per group). The data collection instrument included a pre-tested semi-structured in-depth interview, an FGD guide, and an observation checklist. The collected data were analyzed thematically.FindingsPrevention efforts primarily focused on awareness-raising campaigns and advocacy programs. Control mechanisms were predominantly reactive, including measures such as regulating the substance trade, punishing drug dealers, destroying and burning drug paraphernalia, and closing substance trade centers. The study found limited youth involvement in substance use prevention and control initiatives. Several key challenges were identified in the prevention and control of youth substance use: limited government involvement, reliance only on reactive measures, low youth engagement, insufficient intersectoral collaboration, lack of community commitment, gaps in social institutions, absence of planned interventions, the economic role of substances, government ignorance, and the absence of comprehensive legal frameworks for prevention and control.Conclusion and recommendationThis study highlights a gap in prevention and control mechanisms, and engagement of youths, non-governmental as well as governmental bodies. This study recommends making evidence-based interventions and installing functional networks among sectors to deal with common issues. This issue also should not be left to a single organization and government agencies, families, religious, and educational institutions should play a leading role in tackling substance use burdens at the grassroots level.