bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparative Study between Laparoscopic One Anastomosis Gastric Bypass and Laparoscopic Roux-en-Y Gastric Bypass in Morbidly Obese Patients with Pre-Existing Gastroesophageal Reflux Disease, A Retrospective Study
Authors: Hasan Mashal Anas , Afifi Amr Hamed , Azzam Ahmed Rabee , Elraouf Ahmed Saeed Abd 
Published: November 2024

Abstract

Background
Obesity is a significant problem worldwide, and it is a leading cause of several serious diseases that decrease patient quality of life and increase mortality as well as it is significant risk factor for GERD.

Objective
To compare between RYGB and OAGB regarding improvement of the symptoms of GERD post operative considering the comparison between the two techniques and the complications post operative of the two types of surgeries.

Patients and Methods
This is a retrospective comparative study that will be conducted on Morbidly obese patients with pre-existing GERD. Data of patients will be collected retrospectively starting from march 2017 till the end of February 2021. Approval of the Ethical Committee and written informed consent from all participants will be obtained. 40 morbidly obese patients divided into two groups; group A underwent laparoscopic single anastomosis gastric bypass and group B underwent laparoscopic Roux-en-Y gastric bypass.

Results
This study clarified that OAGB had favorable comparable results with RYGB in patients with obesity having GERD with easier technique, less operative time, and fewer complications. Both procedures have reduced the BMI and PAGI SYM significantly 6 months postoperative. Further larger scale studies for more severe cases of GERD and longer periods of follow-up should be conducted to obtain full picture of the most suitable procedure for weight loss in patients with obesity suffering from GERD.

Conclusion
This study clarified that OAGB had favorable comparable results with RYGB in patients with obesity having GERD with easier technique, less operative time, and fewer complications. Both procedures have reduced the BMI and PAGI SYM significantly 6 months postoperative. Further larger scale studies for more severe cases of GERD and longer periods of follow-up should be conducted to obtain full picture of the most suitable procedure for weight loss in patients with obesity suffering from GERD.
The Effect of Laparoscopic Sleeve Gastrectomy on Gastroesophageal Reflux Disease, A Prospective Observational Study
Authors: Nasr Allah Nasr Khalil El-Azzazi Ahmed Shokry , El-Maleh Mohamed Gamal Elsayed Haitham Mostafa Mohamed , Farrag Ahmed Magdy 
Published: November 2024

Abstract

Background
Obesity, defined by the world health organization as a body mass index (BMI) greater than 30, it is an epidemic issue that has major complications on health. It is estimated that more than 200 million men and 500 million women around the world more than 10% of the world’s population are obese.

Aim of the Work
to examine the effects of LSG on GERD. Depending on gastroesophageal Reflux Disease-Health-Related Quality of Life (GERD-HRQL) questionnaire before and after undergoing elective LSG by 6 months (at least) and result will be confirmed by pH metry for positive cases only (score &gt;35).

Patients and Methods
This study is a prospective observational study. Conducted patients from outpatient clinic of the general surgery department in Ain Shams university hospitals during the period starting from August 2022, till March 2023.

Results
Regarding the GERD-HQOL score distribution among study group (n = 100), we found that There were 92 cases (92%) score &lt;35 &8patients (8.0%) score &gt;35; with ranged score 0-38 with mean 14.73±4.27. Regarding the Relation between positive GERD- HQOL score and pH metry (n = 8) among study group, we found that there was a 8 patients were positive GERD-HQOL out of them 7 patients were positive pH metry with agreement 87.5% while there was one cases were negative pH metry, with p-value &lt;0.001 highly significant.

Conclusion
we found that GERD-HQOL Questionnaire is comparable to pH metry with high index of agreement between questionnaire and pH metry after LSG.
The Use of Tissue Markers of Kidney Injury KIM1 and NAG to Compare between Effect of Extra Corporeal Shock Wave Lithotripsy and Retrograde Intrarenal Surgery on Renal Tissue for Early Detection of Kidney Injury in Managing Renal Stone ≤ 2 cm
Authors: Mahmoud Mahmoud Ahmed , Reyad Essam , Essily Khaled El , Hanna David Raef Kamal , Awady Hossam El 
Published: November 2024

Abstract

Background
Retrograde Intrarenal surgery (RIRS) and Extracorporeal shock wave lithotripsy (ESWL) are well-established treatment options for treatment of kidney stones. Kidney injury molecule 1 (KIM-1) and N-acetyl-β-D-glucosaminidase (NAG) are two proteins secreted by the kidney into the urine and have been found to be sensitive markers of acute kidney injury. The aim of this study is to compare between RIRS and ESWL effect on renal tissue and detect early signs of kidney injury by measuring urinary levels of KIM-1and NAG in patients with kidney stone who were treated by ESWL and RIRS.

Objective
To compare between effect of ESWL and RIRS on renal tissue and detect early signs of AKI through using new biomarkers for AKI (KIM-1, NAG) in managing renal stone ≤ 2 cm

Patients and Methods
This prospective randomized study was conducted in urology department Ain Shams university hospitals and in urology department of Theodor Bilharz Research Institute hospital during the period from 4/2022 till 4/2023 after obtaining Ain Shams university ethics committee approval (No. FWA 000017585).

Results
This study revealed highly statistically significant increased 24-hour post-operative KIM-1/Cr and NAG/Cr in group A (ESWL) (4.59 ± 0.94) and (0.22 ± 0.04) when compared with group B (RIRS) (2.22 ± 0.65) and (0.13 ± 0.03). In group A (ESWL) there was high statistically significant increase in 24-hour post-operative KIM-1/Cr (4.59 ± 0.94) and NAG/Cr (0.22 ± 0.04) when compared with pre-operative KIM-1/Cr (2.26 ± 0.45) and NAG/Cr (0.12 ± 0.04), while in group B (RIRS) there was only statistically significant increased 24-hour post-operative NAG/Cr (0.13 ± 0.03) when compared with pre-operative NAG/Cr (0.11 ± 0.03) with no statistical significant difference between pre-operative KIM-1/Cr (2.22 ± 0.51) and 24-hour post-operative KIM-1/Cr (2.22 ± 0.65).

Conclusion
Patients with known renal impairment or decreased renal functions suffering from renal stone ≤ 2 cm we recommend management of stone using RIRS over ESWL and in case of ESWL being the only option we recommend use of lower number of shock waves per setting.
Early versus Delayed Cholecystectomy in Mild Gallstone Pancreatitis (Prospective Comparative Study)
Authors: Abdelwanis Wael Abdelazim , Kamel Kareem Ahmed , Ragab Khalil Ethar Alaa 
Published: November 2024

Abstract

Background
Gallstone pancreatitis is the most common etiology of acute pancreatitis accounting for up to sixty percent of all cases. In patients with mild gallstone pancreatitis – characterized by the absence of organ failure, peripancreatic fluid collections or necrosis, and typical resolution within one week – cholecystectomy is the definitive treatment.

Aim of the Work
To determine the feasibility of early cholecystectomy during index admission as long as the symptoms and laboratory values are improving for patients with gallstone pancreatitis predicted to be mild on admission and to obtain unbiased estimates of the effect of early cholecystectomy on hospital LOS, complications, and patient-reported outcomes (PROs) in order to determine the need for further evaluation.

Patients and Methods
This Prospective comparative study was conducted at tertiary care hospitals at Ain Shams University hospitals and Nasser institute for medical research and treatment from May 2022 till December 2022 and performed on a total of 20 adult patients who aged 18 years old and over with mild pancreatitis and without cholangitis.

Results
Patients treated with early or late procedure experienced approximately the same intra operative bleeding (30 vs 50%), conversion to open (10 vs 10%), biliary injury (0 vs 0%), and operation time (50 vs 50 minutes) with no statistically significant differences between them (p value= 1.00, 0.65, 0.912) respectively.

Conclusion
Early cholecystectomy after gallstone pancreatitis is more advantageous than late cholecystectomy after gallstone pancreatitis because it is associated with less rate of recurrence of biliary pancreatitis, less complication of pancreatitis, less perioperative complication (adhesions, blood loss, biliary events, infection, postoperative pain) and shorter duration of postoperative hospital stay.
Percutaneous Transluminal Angioplasty as a Treatment of Arteriovenous Fistula Stenosis for Hemodialysis
Authors: Nafei Ahmed Mohammed Khalifa , Abdulrahman Abdulrahman Mohamed Ahmed , Eldieb Khaled Abdelsattar Elsayed , Zayed Hisham Mohammed Ibrahim 
Published: November 2024

Abstract

Background
The main option of renal replacement therapy (RRT) in patients with end stage renal disease (ESRD) is still the hemodialysis (HD). The cornerstone of efficient hemodialysis is the ability to maintain a proper vascular access. The first recommended type of vascular access is the native arteriovenous fistula (AVF) which has a higher patency and lower complication rates compared to other access types such grafts and catheters. Dysfunctional vascular access is a major cause of hospitalization and morbidity in hemodialysis patients.

Objective
To evaluate the endovascular option for treatment of arteriovenous fistula failure stenosis regarding success rates and primary patency rate after the angioplasty procedure at 3, 6 months.

Methods
This is a non-randomized prospective study was conducted at Ain Shams University hospital and Ahmad Maher Teaching hospital. Involving 30 patients having End Stage Renal Disease (ESRD) with failing native AVF.

Results
Percutaneous transluminal angioplasty (PTA) for dysfunctional AVF is an excellent treatment option for AV fistula stenosis. As it has the following advantages: It is more durable than the creation of new access or the catheter placement. Percutaneous transluminal angioplasty (PTA) is relatively simple, less invasive, enables us to spare other access sites for further use, helps in minimizing the insertion of central catheters and allowed the patient to start dialysis in the day after intervention.

Conclusion
PTA has several advantages as it can be considered a safe procedure with low complication rate, less invasive, shorter procedure, enables immediate dialysis without using of central venous catheter, reduces the risk of infection, doesn’t exhaust the patient’s veins and spares them for further use and can be repeated several times before abandoning the fistula.
Comparative Study between Plant Extracts “Lithospermum erythrorhizon” Dressings and Standard Moist Wound Dressings in Management of Diabetic Foot Ulcers
Authors: Kamal Ahmed Mohamed , Ahmed Abdelrahman Mohamed , Zekri Mina Gamil , Abdelazeem Bakheet Mahmoud Elsayed 
Published: November 2024

Abstract

Background
DFU is a common complication of DM that has shown an increasing trend over previous decades. In total, it is estimated that 15% of patients with diabetes will suffer from DFU during their lifetime.

Objective
To compare wound outcome, limb salvage, healing time of diabetes related foot ulcers. and cost effectiveness in terms of usage of hospital resources and numbers and easiness of dressings between Lithospermum erythrorhizon dressings and standard moist wound therapy (SMWT) in management of diabetic foot ulcers.

Patients and Methods
This is a prospective observational study involving 34 patients with active diabetic foot ulcers, in a high-volume tertiary referral vascular center. They were divided into 2 groups: 17 patients (group A) were prescribed SMWD and the other 17 patients (group B) received Lithospermum erythrorhizon wound dressing. Study Period: 6 months from September 2022 to March 2023.

Results
Analyzing the results of our study, we suggest that Lithospermum erythrorhizon wound dressing has a definitive role in promotion of proliferation of granulation tissue, reduction in the wound size, and rapid clearing of bacterial load. Our data demonstrates that Lithospermum erythrorhizon wound dressings decrease the wound depth more effectively than saline gauze dressings over the first 8 weeks of therapy. It is suggested that Lithospermum erythrorhizon wound dressing is a cost-effective, easy to use and patient- friendly method of treating diabetic foot ulcers which helps in early closure of wounds, preventing complications and hence promising a better outcome.

Conclusion
Application of Lithospermum erythrorhizon wound dressing over wound bed increases the effectiveness of local circulation, which assists in the proliferation of granulation tissue and epithelialization. We have also found that the patients on Lithospermum erythrorhizon wound dressing therapy had earlier complete granulation.
Comparative Study for the Outcome of Living Donor Liver Transplantation in Patients with Portal Vein Thrombosis in Comparison to Patients without Portal Vein Thrombosis
Authors: Musalam Muhammad , Khalil Ahmed , Nasser Amr Abdel , Abdelaal Amr , Saber Hatem Sayed 
Published: November 2024

Abstract

Background
Portal vein thrombosis (PVT) is a relative contraindication in living donor liver transplantation (LDLT). We monitored the outcome of adult patients with PVT in comparison to patients without PVT in LDLT.

Methods
This study is a retrospective cohort study. LDLTs that was performed at Liver Transplantation Unit in Air Forces Specialized Hospital and Nasser Institute for Research and Treatment, Cairo, Egypt, between July 2019 to July 2020 were evaluated. 176 cases were divided into two groups according to presence of PVT, group A included 55 recipients who had PVT compared to group B including 121 recipients without PVT.

Results
In our study (N = 176), postoperative PV complications was recorded in 11 cases (6.3%). Five case in each group had postoperative PVT (9.8% versus 4.1%) respectively and a single case of PV stenosis (0.8%) was documented in non-PVT group. All patients who develop early postoperative PV (n = 3/10) complications unfortunately died because of it, unlike those who developed late PV complications, their one year survival rate was 70% of cases (n = 7/10) and the overall mortality rate in patients developed PV complications was 40%; 4 out of 10 cases.

Conclusion
PVT is established not to be a contraindication for liver transplantation but needs complex procedures and sophisticated techniques and Surgeons should be aware with these techniques to restore adequate portal flow in transplant for recipients with PVT.
Breast Surgical Conservation Therapy versus Mastectomy in Multifocal or Multicentric Breast Cancer; A Systematic Review and Meta-Analysis
Authors: Abd El-Moghny Ashraf , Nabil Ahmed , Hanafy Dina Mohamed , Mahmoud Reem Mohamed Korany 
Published: November 2024

Abstract

Background
Breast cancer affects 1.7 million women annually worldwide, the majority of whom are treated surgically. Multiple ipsilateral breast cancers are collectively defined as more than one synchronous ipsilateral cancer at diagnosis. The term Multiple ipsilateral breast cancers denotes either multifocal breast cancers that occur within proximity separated by approximate radiological distances of 20–50 mm of normal tissue, or multicentric cancers occurring further apart in the breast at distances exceeding 50 mm.

Objective
To assess overall survival (OS), local recurrence and cosmetic results between conservative surgical approach and mastectomy in ipsilateral MF and MC breast cancer and to explore whether BCT was feasible for female patients with MF/MC breast cancer.

Patients and Methods
The PubMed, web of science and Scopus were searched on November 2010. The keywords were ipsilateral multiple breast cancer, conservative surgery and Radical mastectomy.

Results
In our Study twelve trials included 1906 patients, six trials regarding comparison between Breast conservative surgery and mastectomy and six trials regarding Breast conservative surgery in the management of the multifocal/multicentric breast lesions. Regarding local recurrence was assessed in six trials comparing between Breast conservative surgery and mastectomy and six trials regarding Breast conservative surgery in the management of the multifocal/multicentric breast lesions.

Conclusion
In MF/MC breast cancer patients, Local and regional recurrence in addition to, distant metastasis in patients undergoing BCT has no statistically difference compared to patients undergoing mastectomy. Further prospective studies should be investigated to refine the prognosis and to optimize the treatment in patients with MF/MC breast cancer.
Comparison of Oncoplastic Breast Surgery and Breast Conserving Surgery without Reconstruction, A Systematic Review and Meta-Analysis
Authors: Ahmady Rania El , Gamal Ahmed , Taalat Mahmoud , Maher Shenouda Malak 
Published: November 2024

Abstract

Introduction
Breast cancer, the second leading cause of cancer-related mortality, poses unique challenges to patients, encompassing physical, emotional, and sexual dimensions. Surgical interventions, such as modified radical mastectomy and breast-conserving surgery (BCS), can exacerbate these challenges. This study explores the integration of oncoplastic breast surgery to address shortcomings associated with traditional approaches.

Methods
A systematic review of PubMed, Web of Science, and Scopus identified 28 relevant studies, encompassing 28,162 patients. Cosmetic outcomes and patient satisfaction were compared between oncoplastic breast surgery (OBCS) and BCS groups, with a focus on psychological and physical well-being domains.

Results
The meta-analysis revealed that OBCS demonstrated superior outcomes in satisfaction with breast appearance, psychological well-being, and physical well-being compared to BCS. Patient satisfaction questionnaire results consistently favored the OBCS group. Recurrence Risk: A meta- analysis estimated a significant reduction in the odds of recurrence in OBCS patients with positive margins (odds ratio = 2.44, P &lt; 0.001). This underscores the oncological safety of oncoplastic techniques. Evolution of Breast Cancer Surgery: Oncoplastic breast surgery represents a pivotal advancement in breast cancer surgery. The convergence of surgical oncology and plastic surgery has allowed continual refinement of techniques, ensuring both oncological safety and improved quality of life.

Conclusion
Accumulating evidence suggests that oncoplastic breast surgery plays a crucial role in achieving wide local resection with enhanced safety margins for malignant breast tumors. By preserving aesthetic and symmetrical breast shapes, oncoplastic procedures contribute to improved patient outcomes, reinforcing the evolving landscape of breast cancer surgery.
Evaluation of Cognition in Mild Cognitive Impairment and Cognitively Intact Group: A Follow Up Study
Authors: Sweed Hala Samir , Kamal Heba Yousif Yousif , Helmy El Malah Dina Mostafa , Hassan Marwa Elsayed Abbas 
Published: November 2024

Abstract

Introduction
Assessment of cognition in elderly is essential. Mild cognitive impairment (that also known as isolated memory impairment or incipient dementia) is a brain function syndrome involving both the evolution and onset of cognitive impairments that is beyond what would be expected based on an individual's age education, but is not significant enough to interfere with their daily activities.

Objective
To evaluate whether there is change of cognition in mild cognitive impairment and control group over a period of 6 months.

Methods
A case control study was conducted on total160 elderly patients (80 person in MCI group and 80 persons in cognitively intact group) that were recruited from ASU hospitals (inpatients and outpatients). All patients underwent comprehensive geriatric assessment and follow up after 6 months by cognitive function tests.

Results
Cognitive assessment at first visit and follow up visit in MCI group regarding MOCA test executive (P = 0.021) and orientation (P = 0.035) were, in case of MMSE attention (P = 0.023), recall (P = 0.034) and language (P = 0.020) were statically significant. Also regarding CDR, orientation (P = 0.005), community affairs (P = 0.028) and home and hobbies (P = 0.042) were statistically significant. While the cognitive assessment of cognitively intact group, that there was no statistical significant regarding MMSE, CDR, MOCA at first visit and follow up visit.

Conclusion
Different cognitive assessment items were affected in MCI group over a 6 month period.
Fracture Risk Assessment in Elderly with Chronic Liver Disease and its Relationship with Serum Albumin Level
Authors: Hamza Sarah Ahmed , Kamel Heba Yousif Yousif , Mohamed Enas Ramadan , Elbehery Hesham Mosad , Hashish Ramy Mahdy Ahmed 
Published: November 2024

Abstract

Background
Falls and fractures have detrimental effect on health of elderly population. Detection of risk factors for this syndrome is crucial in its prevention, especially in populations suffering negative bone alterations such as patients with chronic liver disease (Stains et al., 2020).

Objective
To estimate and detect fracture risk factors among elderly with chronic liver disease and relation to serum albumin level.

Subjects and Methods
A case control study included total number of one hundred and thirty (130) participants recruited form the geriatric outpatient clinic in Ain Shams university hospital in Cairo and chosen by convenience sampling method. The study sample was distributed into two groups: cases (n = 65) with positive history of falls, fall related fracture or risk falls, while controls (n = 65) were negative for these factors. All subjects underwent comprehensive geriatric assessment with focus on liver disease, drug history, assessment of risk of falls using timed up and go test (TUG), with radiological assessment for chronic liver disease and laboratory assessment for serum albumin

Results
Age difference between cases and controls was statistically significant, where cases had higher mean (74.37 ± 7.17) compared to that of the control group (67.12 ± 5.81). the cases group had higher prevalence of females (66.2%) compared to the control group (44.6%). The diagnosis of hepatic focal lesion was also more prevalent among cases compared to controls (13.8% vs 1.5%). Lower serum albumin levels were found among cases (3.1 ± 0.46) compared to controls (3.1 ± 0.46).

Conclusion
Higher age, female sex and lower serum albumin level were associated with higher risk of falls, falls and fall related fractures in patients with chronic liver disease. Categories: Preventive Medicine, Public Health, Geriatrics.