bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual and Cognitive Demands of CarPlay, Android Auto, and Five Native Infotainment Systems
Authors: Strayer David L. , Cooper Joel M. , McCarty Madeleine M. , Getty Douglas J. , Wheatley Camille L. , Motzkus Conner J. , Goethe Rachel M. , Biondi Francesco , Horrey William J. 
Published: April 2019

Objective: The present research compared and contrasted the workload associated with using in-vehicle information systems commonly available in five different automotive original equipment manufacturers (OEMs) with that of CarPlay and Android Auto when used in the same vehicles. Background: A growing trend is to provide access to portable smartphone-based systems (e.g., CarPlay and Android Auto) that support an expansion of various in-vehicle infotainment system features and functions. Method/Results: The study involved on-road testing of 24 participants in each configuration of five vehicles crossed with the three different infotainment systems: the embedded portion of the native OEM systems, CarPlay, and Android Auto. Our analysis found that workload was significantly greater for the embedded portion of the native OEM systems than for CarPlay and Android Auto. The strengths and weaknesses of each CarPlay and Android Auto traded off in such a way that the overall demand associated with using the two systems did not differ. Conclusion: CarPlay and Android Auto provided more functionality and resulted in lower levels of workload than the embedded portion of the native OEM infotainment systems. Application: Potential applications of this research include refinements to CarPlay and Android Auto to address variations in workload as a function of task type, the modality of interaction, and OEM implementation of the system.
Influence of Textured Indoor Footwear on Posture Stability of Older Women Based on Center-of-Pressure Measurements
Authors: Li Pui-Ling , Yick Kit-Lun , Ng Sun-Pui , Yip Joanne 
Published: April 2019

Objective: The objective of this study is to evaluate the efficacy of indoor footwear with a textured surface to improve control of balance and reduce excessive plantar pressure in older women. Background: Balance instability is a common condition in older people. Textured insoles with protrusions on the entire insole have been examined for enhancing somatosensory feedback in the elderly to improve control over balance. However, these insoles have significant challenges in distributing the plantar pressure. Textured insoles with tailored protrusions should be therefore investigated for the same purpose but provide better plantar pressure distribution. Method: A total of 24 older women have undergone both static standing and walking tests with the use of the in-shoe Pedar® system. Results: The results indicate that wearing textured indoor footwear provides a significant reduction in postural sway, particularly in the medial–lateral direction during walking. As compared to walking barefoot, the center-of-pressure trajectory when wearing the textured indoor footwear remains supported with less variance among the steps, which is statistically significant in the medial–lateral direction. A significant reduction in the peak pressure is found in the forefoot and rearfoot regions as the plantar pressure is redistributed to the midfoot regions. Conclusion: The textured surface of the insole improves balance control of older women and effectively reduces foot pressure at high pressure areas. Application: The findings enhance current understanding on textured footwear as a form of intervention associated with changes in functional impairments, therefore providing basis for footwear design in balance control.
Social Determinants of Human Papillomavirus Vaccine Uptake: An Assessment of Publicly Available Data
Authors: Maness Sarah B. , Thompson Erika L. 
Published: April 2019

Objectives: Despite cancer prevention benefits associated with the human papillomavirus (HPV) vaccine, uptake in the United States is relatively low among males and females. Our objective was to use the Healthy People 2020 social determinants of health framework to determine the availability and characteristics of data on economic, educational, social, health care, and community factors affecting HPV vaccine uptake in the United States. Methods: We included the most recent data sets from 6 publicly available, US-based, federally funded surveys that contained at least 1 measure of HPV vaccination among adolescents and young adults. We searched each data set for any social determinants of health measures within the 5 domains of the framework: economic stability, education, social and community context, health and health care, and neighborhood and built environment. Results: The social determinants of health domains of education, economic stability, and health and health care appeared in all data sets. The domains of social and community context and neighborhood and built environment appeared in only 3 data sets. Even when domains were represented, we discovered gaps in the data sets, in which only limited measures of the social determinants were available. Conclusion: The addition of questions about the social determinants of health to the surveys that generate these data sets, particularly in the domains of social and community context and neighborhood and built environment, would strengthen the ability of public health researchers, policy makers, and professionals to identify associations between the social determinants of health and HPV vaccine uptake.
Variations of the proprotein convertase subtilisin/kexin type 9 gene in coronary artery disease
Authors: Chiang Shih-Min , Yang Yi-Sun , Yang Shun-Fa , Tsai Chin-Feng , Ueng Kwo-Chnag 
Published: April 2019

Objective Coronary artery disease (CAD) is the principal cause of mortality and morbidity worldwide. Studies have provided controversial results regarding whether variations in the proprotein convertase subtilisin/kexin type 9 gene ( PCSK9) are risk factors for CAD. In this study, we evaluated the risk factors associated with PSCK9 genotypes and CAD in the Taiwanese population. Methods A total of 501 patients diagnosed with CAD by angiography and 334 CAD-free controls were recruited. Two single nucleotide polymorphisms of PSCK9 (rs505151 and rs529787) were genotyped. Results The prevalence of a positive family history for CAD was significantly higher in individuals carrying the AG + GG genotype of the PSCK9 rs505151 polymorphism. Among CAD patients with a positive family history, the prevalence of diabetes mellitus was significantly higher in those carrying the AG + GG genotype of the PSCK9 rs505151 polymorphism (73.3%) than in those carrying the AA genotype (39.2%). Conclusion In CAD patients, the AG genotype of PSCK9 rs505151 is associated with diabetes and a positive family history of CAD.
Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine in children and adolescents, 1st edition
Authors: Abu-Arafeh Ishaq , Hershey Andrew D , Diener Hans-Christoph , Tassorelli Cristina ,   on behalf of the Clinical Trials Standing Committee and the Child and Adolescent Standing Committee of the International Headache Society
Published: April 2019

Background Because the results of clinical trials of investigational treatments influence regulatory policy, prescribing patterns, and use in clinical practice, high quality trials are an essential component of the evidence base for migraine. The International Headache Society has published guidelines for clinical trials in adults with migraine since 1991. With multiple issues specific to children and adolescents with migraine, as well as the emergence of novel trial designs and advances in pharmaceuticals, biologics, devices, and behavioural interventions, there is a need for guidance focusing on issues specific to the conduct of clinical trials in children and adolescents with migraine. Objectives The objective of these guidelines is to provide a contemporary, standardized, and evidence-based approach to the design, conduct, and reporting of well-controlled clinical trials of preventive treatment of migraine in children and adolescents. Methods The development of these guidelines was based on guidelines previously published by the International Headache Society and regulatory bodies. The recommendations are evidence-based, where available. The process included consultations among various committees, roundtable discussions among stakeholders (lay people and the pharmaceutical industry), and open consultation with the IHS membership on the final draft. Results A series of recommendations addressing the major issues in clinical trials in children and adolescents with migraine is provided. Recommendations are supported by evidence-based practice and validated methodologies, where available. Supporting comments are provided to clarify ambiguities. Conclusions These guidelines should be consulted and used in designing and conducting clinical trials of preventive treatments in children and adolescents with migraine.
Attending to Total Pain in Juvenile Huntington Disease: A Case Report Informed by Narrative Review of the Literature
Authors: Kendrick Lindsey M. , Hudgell Denise , Hellman Amy , Weaver Meaghann S. 
Published: April 2019

Objectives: To consider the impact of juvenile Huntington disease (JHD) from a biomedical, symptom burden, and total pain palliative care perspective. Methods: This case report was informed by a narrative review of the literature with inclusion of expert opinion from pediatric palliative care, an adult and pediatric neurologist, and a child psychiatrist. Audio-recorded qualitative interview and coauthorship with the pediatric patient’s primary caregiver (his mother). Results: The JHD impacts all domains of child and family function. Significance of Results: Application of the concept of total pain to JHD informs and guides care for this complex, challenging condition.
Nursing Students Learn Online Interprofessional Education on Substance Use
Authors: Puskar Kathy , Mitchell Ann M. , Lee Heeyoung , Kane Irene , Albrecht Susan A. , Frank Linda R. , Hagle Holly , Lindsay Dawn , Kameg Brayden , Johnson Cortney , Sun Ran 
Published: April 2019

BackgroundInterprofessional education strategies are becoming more prevalent as nursing schools integrate interprofessional practice activities into their curricula.PurposeThis paper presents the results of a federally funded project to deliver online interprofessional education to nursing students on screening for alcohol and substance use in rural areas, in which their perceptions about interprofessional education were measured.MethodsA quasi-experimental within-subjects repeated measures design was utilized. Students in the bachelor or associate degree program were recruited from two rural nursing schools. A demographic questionnaire, Alcohol and Alcohol Problems Questionnaire, Drug and Drug Problems Questionnaire, and Interprofessional Education Perception Scale were utilized. General linear modeling was used to determine changes in these measurements over time. Data collection was performed at pretraining, posttraining, and following an online interprofessional dialogue.ResultsThe study consisted of 89 nursing students. The participants were 87% female (n = 77/89) and 91% white (n = 81/89); their mean age was 24.9 years (standard deviation = 10.36). Analysis of evaluation questionnaires demonstrated increased levels of confidence in working with patients who consume alcohol or other drugs and on certain aspects of interprofessional education.ConclusionOnline interprofessional preservice education holds the potential to positively increase nursing students’ confidence in working with patients and to increase their interprofessional practice.
Examination of Barriers to Medication Adherence, Asthma Management, and Control Among Community Pharmacy Patients With Asthma
Authors: Makhinova Tatiana , Barner Jamie C. , Brown Carolyn M. , Richards Kristin M. , Rascati Karen L. , Rush Sharon , Nag Arpita 
Published: April 2019

Objective: To describe the prevalence of common barriers to asthma medication adherence and examine associations between patient-reported asthma controller adherence and asthma control, therapy adherence barriers, and asthma management characteristics. Methods: Previously developed asthma-specific tool was pilot tested on a convenience sample of adult patients with persistent asthma. The following data were collected via patient survey: demographic characteristics and comorbidities, adherence, asthma control, and asthma management characteristics. Descriptive and inferential statistics were used to address the study objective. Results: The patients (N = 93) were 45.4 (17.2) years of age, and 66.7% were female. The majority had poor (68.8%) adherence, with 61.3% of patients having controlled asthma. There was no significant association between adherence and asthma control. The mean number of barriers for good and poor adherence groups differed significantly: 2.0 ± 1.1 and 5.4 ± 2.4, respectively ( P < .0001). Having an asthma action plan (AAP) was the only asthma management characteristic significantly related to adherence. The majority of patients with poor adherence did not have an AAP (76.6%), whereas 81.5% of patients with good adherence did have an AAP ( P < 0.0001). Conclusions: The use of this survey tool confirmed presence of asthma-specific barriers, thus using this specialized approach may lead to more effective, targeted counseling in community pharmacy settings.
Prospective comparison of perioperative wound and pain score parameters in cats undergoing flank vs midline ovariectomy
Authors: Swaffield Matthew J , Molloy Sara L , Lipscomb Victoria J 
Published: April 2019

Objectives The aim of this study was to prospectively compare perioperative pain score and wound parameters, inclusive of postoperative swelling and erythema, between flank and midline ovariectomy (OVE) in cats, performed by final-year veterinary students. Methods Healthy cats presented for routine OVE were randomly assigned to either the midline or flank group after owner consent to participate in the study. Perioperative protocols were standardised for both groups. Clinical data were collected prior to surgery, intraoperatively, at 1 h postoperatively, at the time of discharge, and at 3 and 10 day postoperative re-examination appointments. Data recorded included duration of surgery and anaesthesia, intraoperative complications, Feline Acute Pain Scale (FAPS) scores, a simple descriptive scale of reaction to wound palpation (SDSwound), a dynamic and interactive visual analogue scale assessment of pain (DIVAS), and both a simple descriptive scale (SDSswelling) and a visual analogue scale (VASswelling) of surgical wound swelling. Results Thirty-eight cats received a flank OVE and 37 received a midline OVE. Duration of surgery, duration of anaesthesia and intraoperative complications did not vary significantly between the two groups. Cats in both groups had significantly higher FAPS scores after surgery ( P = 0.0002), with cats receiving a flank OVE having significantly higher pain scores compared with a midline OVE at 1 h postoperatively ( P = 0.0004) and at discharge ( P = 0.002). Swelling of the surgical wound (SDSswelling) was significantly higher in cats receiving a midline OVE at the time of discharge ( P = 0.048), as well as at the 3 day ( P <0.0001) and 10 day ( P = 0.001) postoperative re-examinations. FAPS scores were significantly higher in cats receiving a midline OVE at the 3 day ( P = 0.016) and 10 day re-examinations ( P = 0.045). No cats in either group suffered a wound breakdown or infection. Conclusions and relevance Our study does not support advocating a preferred surgical approach for feline OVE within a teaching environment.
Major factors affecting intraocular pressure spike after intravitreal ranibizumab injection: Vitreous reflux and its amount
Authors: Uyar Enes , Ulas Fatih , Sahin Saygin , Celebi Serdal 
Published: April 2019

Purpose:The aim of this study was to assess the effect of vitreous reflux and its amount on short-term intraocular pressure after intravitreal injection of ranibizumab.Methods:The study included 316 eyes of 276 patients. Intraocular pressures were measured before intravitreal injection (preIOP), immediately after intravitreal injection (postIOP0), and 30 min after intravitreal injection (postIOP30). The amount of vitreous reflux was evaluated by measuring conjunctival bleb diameter, and patients were grouped as; group 1: no vitreous reflux, group 2: less vitreous reflux, and group 3: more vitreous reflux. The data were analyzed using variance analysis, chi-square test, and regression analysis.Results:PostIOP0 values were highest in group 1, followed by group 2 and group 3 (all p values < 0.001). PostIOP30 values were similar in group 1 and group 2 (p = 0.261), but were lower in group 3 than other two groups (p < 0.001, p = 0.001, respectively). Vitreous reflux was identified as the only factor affecting postinjection intraocular pressure changes (p < 0.001), and a negative correlation was found between the total number of intravitreal injection and vitreous reflux (p = 0.032).Conclusion:The major factor affecting short-term postinjection intraocular pressure elevation was vitreous reflux, and intraocular pressure levels increased as the amount of vitreous reflux decreased. Vitreous reflux and its amount decreased as the total number of intravitreal injection increased.
Isolated cilioretinal artery occlusion secondary to perinuclear antineutrophil cytoplasmic antibody vasculitis
Authors: Mammo Danny A , McClelland Collin M , Chen John , Adams Matthew K , Pulido Jose , Davies John B 
Published: April 2019

Introduction: Antineutrophil cytoplasm antibody-associated vasculitides encompass a diverse spectrum of autoimmune diseases characterized by necrotizing small vessel vasculitis. Ocular manifestations may be the presenting findings of antineutrophil cytoplasm antibody-associated vasculitides. Methods: Single, retrospective case study. Results: We report the rare case of a 55-year-old woman with a cilioretinal artery occlusion as the presenting feature of perinuclear antineutrophil cytoplasm antibody-associated microscopic polyangiitis. Conclusions: Although rare, antineutrophil cytoplasm antibody-related vasculitis should be considered in any retinal vascular occlusion, particularly in the setting of patients with new vague headaches and a paucity of vasculopathic risk factors.
The Indian Inflation 2006–2016: An Econometric Investigation
Authors: Mukherjee Paramita , Coondoo Dipankor 
Published: April 2019

Recently several changes have been adopted in the conduct of monetary policy in India, like tracking CPI (Consumer Price Index), targeting inflation and so on. However, certain curious features of inflation may have some implications on the effectiveness of such measures. This article tries to explore the nature of inflation during the last decade. There are certain views about the nature of Indian inflation from the structuralist perspective. This article contributes to the literature by empirically testing those propositions and coming out with some significant policy implications. The article is based on monthly data from January 2006 to March 2016. By employing econometric techniques like cointegration and vector autoregression (VAR), the article tries to explain the movements of different components of WPI (Wholesale Price Index) and CPI inflation, both core and headline inflation and how they are related to macroeconomic policy variables. The empirical analyses focus on finding out the existence of co-movements among the inflation and macroeconomic variables, explaining the role of components like food and fuel price in driving CPI and WPI. The results have some important policy implications. First, the movements of WPI and CPI and their headline and core counterparts are not explained by same set of variables. Second, food inflation is not explained by agricultural output pointing to the insufficient increase in supply in agriculture. Third, the determinants of CPI headline and core inflation are not same. So, both of them should be tracked while formulating policies. The relationship among the components of inflation point to the possibility of some adjustment in demand from one set of goods to another, implying adjustments in terms of relative prices which needs further exploration. JEL: E31, E52, C32
The Economic Impact of Road Accidents: The Case of Sri Lanka
Authors: Bhavan Thangamani 
Published: April 2019

The purpose of this study is to disclose accident-related indices and investigate the extent to which the road accidents impact on the economic performance of Sri Lanka during the period from 1977 to 2016. Annual time-series data are used to evaluate the accident indices for econometric analysis. Augmented Dickey–Fuller (ADF) unit root analysis and Johansen’s maximum likelihood estimator of the parameters of a cointegrating vector error correction model (VECM) are employed to test the stationary properties of the time series and to examine the long-run relationship between the variables, respectively. The results derived from the analysis confirm the existence of long-run relationship between the accident-related indices and macroeconomic indicators. The long-run elasticity values imply the signs and magnitude of impact of the accident indices on macroeconomic indicators. JEL: R41, H510, I310, I32
India–China Trade: Asymmetrical Developments and Future Prospects
Authors: Ghosh Sunandan , Agarwal Manmohan , Banerjee Adrita 
Published: April 2019

This article seeks to provide an overview of the evolution and analyses the changing composition of trade between India and China over the period 1983–2017. We find that Chinese exports are almost completely concentrated in manufactures, especially finished equipment goods, whereas Indian exports consist of both agriculture and manufactures and over time have shifted predominantly to intermediate goods. Further, both the countries are exporting those commodities to each other in which they have a revealed comparative advantage, with China’s exports being more diversified. We employ vector error correction estimation and show that China’s exports to India are dependent on India’s household consumption expenditure, while India’ exports to China are correlated to Chinese manufacturing value added. Finally, we calculate the share of each country’s commodity-wise export to the partner in their respective total exports with a view to studying prospects for India–China trade. We conclude that for further trade expansion, diversification is extremely necessary, and Indian exports of inputs to Chinese industries need to change substantially to accommodate the changing nature of China’s industrial structure. JEL: F14, F15, O24