bluuebunny/crossref_metadata_2025_split huggingface dataset:
The efficacy of an endoscopic endonasal approach in the repair of cerebrospinal fluid fistula: a clinical analysis
Authors: Ozer Fulya , Cagici Can Alper , Ozer Cem , Yilmazer Cuneyt 
Published: March 2019

<p class="abstract"><strong>Background:</strong> Cerebrospinal fluid (CSF) fistula is an abnormal CSF leakage due to bone and/or dural defect of the skull base and usually operated with endonasal endoscopic approach. The aim of this study was to determine the efficacy of an endonasal endoscopic approach in the repair of CSF leakage and to find the reasons of the recurrence of endoscopic procedure.</p><p class="abstract"><strong>Methods:</strong> The medical records of 24 patients that presented with the diagnosis of cerebrospinal fluid fistula and who had undergone endonasal endoscopic repair surgery were reviewed retrospectively. </p><p class="abstract"><strong>Results:</strong> 13 patients (54.2%) were found to have spontaneous CSF fistulas without any history of trauma, while 11 patients (45.8%) had posttraumatic CSF fistulas. The mean body mass index (BMI) of patients was 31. 3 kg/m² (20.1-49.6). Nasal septal cartilage was used as a graft material in 19 patients (79%) while only fascia was used in 5 patients (21%). The evaluation of long-term results revealed recurrence in 4 patients (16.6%). Two of these patients required a second surgical repair.</p><p class="abstract"><strong>Conclusions:</strong> An endoscopic endonasal approach is a safe method with less morbidity and a reliable outcome in the repair of CSF fistulas. The most important causative factors in the recurrence of endoscopic repair of CSF leak might be to have high BMI and not to use multilayered graft material for closure of fistula.</p><p class="abstract"> </p>
Advanced Control Techniques for Enhance the Power System Stability at OOS Condition
Authors: Eltamaly Ali M. , Mohamed Yehia Sayed , El-Sayed Abou-Hashema M. , Elghaffar Amer Nasr A. 
Published: March 2019

<p>The power system stability is the accurate operation of the electric grid by restoring balance after being subjected to an abnormal condition such as fault, line switching, load rejection, and loss of excitation. Protective equipment in high voltage substations should fast and precisely localize the faults. Some abnormal conditions in the power system such as out-of-step (OOS) condition which is not a real fault, but the protection equipment will consider it is. This misjudgment will cause the loss of synchronism between areas within the power system or between interconnected systems and will lead to blackout of the national grid. This paper studied the OOS condition, philosophy of protection relay device and how to avoid the false operation for distance function by Out of Step Blocking (OSB) by using the advanced protection relay, to improve the stability of power system. </p>
Cost-Effectiveness of Wound Care: A concept analysis
Authors: Al-Gharibi Koukab A. , Sharstha Sajana , Al-Faras Maria A. 
Published: March 2019

This review aimed to analyse the concept of cost-effectiveness within the context of chronic wound care using Walker and Avant’s approach. The Cumulative Index to Nursing and Allied Health Literature® (EBSCO Information Services, Ipswich, Massachusetts, USA), MEDLINE® (National Library of Medicine, Bethesda, Maryland, USA) and Nursing & Allied Health® (ProQuest LLC, Ann Arbor, Michigan, USA) databases were searched using a combination of keywords. A total of 18 peer-reviewed articles were identified. In wound care, defining attributes for the concept of cost-effectiveness encompassed treatments which were both effective and economical. Four antecedents were identified, including the type of wound, care setting, type of dressing and patient-related characteristics. The consequences of cost-effective wound care were patient prognosis, quality of life, the economic burden on the patient and healthcare system and cost-savings. These findings will hopefully help to standardise cost-effectiveness terminology among nursing professionals in various healthcare settings.Keywords: Cost Effectiveness; Wounds and Injuries; Healthcare Costs; Nursing; Concept Formation.
Pharmaceutical Care in Children: Self-reported knowledge, attitudes and competency of final-year pharmacy students in Jordan
Authors: Mukattash Tareq L. , Jarab Anan S. , Abu-Farha Rana K. , Alefeishat Eman , McElnay James C. 
Published: March 2019

Objectives: Pharmacists require a baseline level of knowledge in paediatric pharmaceutical care in order to be able to adequately care for paediatric patients and counsel their families. This study aimed to explore the self-reported knowledge, attitudes and competency of final-year pharmacy students in Jordan regarding paediatric pharmaceutical care. Methods: This study took place in Jordan between November 2016 and May 2017. A 28-item questionnaire was designed and administered to 400 students from all pharmacy programmes in Jordan during their final year of training. Results: A total of 354 students agreed to take part in the study (response rate: 88.5%). Most respondents (95.2%) were aware of the term ‘paediatrics’. However, almost one-third of the respondents (30.5%) reported never having taken paediatric dose calculation courses and more than half (55.6%) were unfamiliar with the term ‘off-label medicines’. Moreover, most respondents (65.1%) had low knowledge scores (≤2 out of 5) when presented with realistic paediatric case scenarios. There were no significant differences in knowledge and attitudes between undergraduate and doctoral students or between those from public or private universities (P >0.05). Conclusion: The findings of this study highlight an alarming deficiency in paediatric pharmaceutical knowledge among final-year pharmacy students in Jordan. As such, paediatric-related content should be emphasised in the pharmacy curricula of Jordanian universities so that pharmacy students receive more formalised education and more extensive training in this area.Keywords: Pharmaceutical Care; Pediatrics; Pharmacy Students; Knowledge; Attitudes; Competency-Based Education; Jordan.
Development and Validation of a Cross-Cultural Heart Failure-Specific Quality of Life Questionnaire
Authors: Mohamed Nor F. , Ghazali Siti R. , Yaacob Nor A. , Rahim Aizai A. A. , Maskon Oteh 
Published: March 2019

Objectives: Heart failure (HF) is a common clinical syndrome with an enormous impact on prognosis and lifestyle. Accordingly, rehabilitation measures need to be patient-specific and consider various sociocultural factors so as to improve the patient’s quality of life (QOL). This study aimed to develop and validate a HF-specific QOL (HFQOL) questionnaire within a multicultural setting. Methods: This study took place at the National Heart Institute and Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia, between March 2013 and March 2014. A self-administered 75-item HFQOL questionnaire was designed and administrated to 164 multi-ethnic Malaysian HF patients. Exploratory factor analysis was performed to assess the instrument’s construct validity. Cronbach’s alpha coefficients were used to determine internal consistency. Results: A total of 33 out of 75 items were retained in the final tool. The HFQOL questionnaire had three common factors—psychological, physical-social and spiritual wellbeing—resulting in a cumulative percentage of total variance of 44.3%. The factor loading ranges were 0.450–0.718 for psychological wellbeing (12 items), 0.394–0.740 for physical-social wellbeing (14 items) and 0.449–0.727 for spiritual wellbeing (seven items). The overall Cronbach’s alpha coefficient of the questionnaire was 0.82, with coefficients of 0.86, 0.88 and 0.79 for the psychological, physical-social and spiritual wellbeing subdomains, respectively. Conclusion: The HFQOL questionnaire was found to be a valid and reliable measure of QOL among Malaysian HF patients from various ethnic groups. Such tools may facilitate cardiac care management planning among multi-ethnic patients with HF.Keywords: Heart Failure; Quality of Life; Culturally Competent Care; Ethnic Groups; Questionnaire Design; Reliability and Validity; Malaysia.
Design, Implementation and Testing of a Novel Prototype Orthotic Knee Joint with Two Degrees of Freedom in a Patient with Medial Knee Osteoarthritis
Authors: Aghajani-Fesharaki Siamak , Farahmand Farzam , Saeedi Hassan , Abdollahy Ehsan 
Published: March 2019

Knee braces are a conservative treatment option for patients with knee osteoarthritis (KOA). However, no commercially available orthotic knee joint currently reflects natural knee movements. A prototype orthotic knee joint with two degrees of freedom (DOF) in the sagittal and transverse planes was developed to more closely simulate the natural motion of the knee joint. The prototype was tested on a male subject with medial KOA during a sit-to-stand task. The efficacy of the transverse plane DOF was assessed by comparing the limb-orthosis interaction force when the transverse plane was locked to mimic a one-DOF setting versus when it was unlocked. Unlocking the transverse plane eliminated the 45-Newton shearing force produced with the one-DOF setting at wide angles of flexion. The two-DOF orthotic knee joint prototype demonstrated greater conformity to natural knee movements, allowing the wearer to better tolerate bracing-related difficulties. Keywords: Knee Joint; Knee Osteoarthritis; Orthotic Devices; Braces; Rotation; Movement; Materials Testing.
Hypercalcaemia: A portent of sarcoidosis in cystic fibrosis
Authors: B. Jayakrishnan , Al-Mubaihsi Saif M. , Kashoub Masoud S. , George Jojy 
Published: March 2019

The coexistence of cystic fibrosis (CF) and sarcoidosis is rare. We report a 22-year-old male cystic fibrosis patient who presented multiple times to the Sultan Qaboos University Hospital, Muscat, Oman, in 2013. He was diagnosed with non-parathyroid-related hypercalcaemia and anterior uveitis, while computed tomography revealed mediastinal and abdominal lymphadenopathy and mild hepatosplenomegaly. These findings, in addition to the presence of calciuria and a high angiotensin-converting enzyme (ACE) level, confirmed a clinical diagnosis of sarcoidosis. The patient responded well to treatment with oral prednisolone which, over the course of two years, resulted in the near-complete resolution of parenchymal nodular infiltrates, regression of hilar lymphadenopathy, resolution of hypercalcaemia and the normalisation of his ACE levels. Diagnosing pulmonary sarcoidosis in CF can be challenging as most adult patients already have extensive lung disease. Physicians should be aware that hypercalcaemia may be an early manifestation of sarcoidosis in such cases.Keywords: Sarcoidosis; Cystic Fibrosis; Hypercalcemia; Case Report; Oman.
A Rhinofacial Conidiobolus coronatus Fungal Infection Presenting as an Intranasal Tumour
Authors: Deak Levente , Mudalagiriyappa Savitha , Ballin Annelyse , Saxton David , Chakrabarti Arunaloke 
Published: March 2019

Conidiobolomycosis is a rare fungal infection that affects adults in tropical regions. We report a 42-year-old male patient who was referred to the Sulaiman Al Habib Hospital, Dubai, United Arab Emirates (UAE), in 2013 with excessive nasal bleeding and a suspected nasal tumour. He reported having briefly visited central India nine months previously. Computed tomography and magnetic resonance imaging showed a highly vascularised mass in the nasal cavity. However, after surgical excision, initial treatment with amphotericin B deoxycholate was unsuccessful and the disease progressed, leading to external and internal nasal deformation and necessitating further excision and facial reconstruction. Histopathological analysis of the second biopsy revealed Splendore-Hoeppli changes consistent with a fungal infection. Microbiological findings subsequently confirmed Conidiobolus coronatus. Subsequently, the patient was successfully treated with a combination of itraconazole and fluconazole. To the best of the authors’ knowledge, this is the first report of a case of rhinofacial conidiobolomycosis from the UAE.Keywords: Nasal Obstruction; Conidiobolus; Zygomycosis; Antifungal Agents; Case Report; United Arab Emirates.
The relationship between prosocial behaviours, aggression types and moralâ€”social rule knowledge in preschool children
Authors: Dereli Esra 
Published: March 2019

The objective of the present study was to investigate prosocial behaviour, aggression types and moral and social rule knowledge perceptions of 4â€“5 year old preschool children. The study sample included 310 children (154 female and 156 male), who were attending a pre-school education institution during the 2017â€“2018 academic year. A personal information form, Pre-School Social Behavior Scale-Teacher Form and Moral and Social Rule Knowledge Perception Scale were used as data collection instruments. The data were analysed with descriptive analysis, Pearson product-moment correlation coefficient and stepwise regression analysis. In the study, it was determined that there were moderate significant correlations between prosocial behaviour, aggression types and moral and social rule knowledge perceptions of 4â€“5 year old preschool children. It was also determined that prosocial behaviour and aggression types scores of the children significantly predicted their moral and social rule knowledge perception scores.
Keywords: Prosocial behaviours, aggression types, moral rule knowledge, social rule knowledge.
The content analysis of the English as an international language-targeted coursebooks: English literature or literature in English?
Authors: Solhi Andarab Mehdi 
Published: March 2019

The integration of literature and literary works has always played an undeniable role in language education. Despite the existence of a wealth of literature in non-native English-speaking countries, in the majority of the coursebooks, the entire attention is devoted to literary works of the native English-speaking countries. In this study, five coursebooks claiming to be based on English as an international language (EIL) were randomly selected and analysed to investigate to what extent they have incorporated the literatures of native and non-native English-speaking countries. The criteria for the content analysis of the claimed EIL-based coursebooks were based on Kachruâ€™s Tri-Partide Model to categorise the countries, and culture with a small c and Culture with a capital C dichotomy. Results indicated that although the chosen coursebook purports to be based on EIL, less or nearly no attention is given to the literary works of the non-native speakers of English.

Keywords: ELT coursebooks, English as an international language, Kachruâ€™s Tri-Partide model, literature in English
The effect of endodontic filling agents on the activity of the regeneration processes of bone tissue in the experiment
Authors: Han Iryna , Musij-Sementsiv Khristina , Zubachyk Volodymyr 
Published: March 2019

Introduction. Highly important is to regenerate the inflammatory destructive processes of bone tissue outside the apical area of the tooth that would optimize reparative bone formation, mineralization of tooth tissues, restoration of periodontal function and stability of tooth to occlusive loads, especially with acquired extensive root apex. Low efficiency of endodontic treatment led to the searching of the new osteotropic drugs of osteoconductive action and biorevitalization to stimulate the repairing and regeneration of tissues outside the apical area and dense obturation of the apex of the tooth root.Aim. of our research was to determine the dynamics of reparative processes in the bone tissue under the influence of drugs and compositions for endodontic treatment based on an analysis of indicators of a mineral metabolism, marker enzymes and an activity of antioxidant system and lipid peroxidation.Material and Methods. An experiment was conducted on 120 white rats. It was created a bone defect, which was filled with studied biomaterials or left with a blood clot. From the experiment the rats were taken out on 14 and 90 day. In homogenates of bone tissue it was examined the activity of lysosomal enzymes — alkaline (ALP) and acid (AP) phosphatases and the content of microelements — calcium and phosphorus. In the blood of rats it was studied the concentration of general protein, lipid peroxidation products — malonic dialdehyde (MDA) and the enzyme activity of antioxidant system — catalase (CAT) and superoxide dismutase (SOD).Results and conclusions. Results of conducted experimental research of the effect of endodontic filling materials on the activity of the regeneration processes of bone tissue show that proposed compositions based on hydroxyapatite and beta-tricalcium phosphate, due to their osteoconductive and biorevitalization qualities, promote more active stimulation of bone tissue regeneration processes compared to generally accepted drugs.
HPV-related HNC – new challenge and hope for head and neck cancer subjects
Authors: Szyfter Krzysztof , Kiwerska Katarzyna , Wierzbicka Małgorzata 
Published: March 2019

In recent years there are observed substantial changes in epidemiology of head and neck cancer. An incidence of laryngeal cancer is declining as a consequence of decreased tobacco smoking. Contrary, oropharyngeal cancer associated with HPV infection transmitted on sexual way is becoming much more frequent. The latter one is characterized with a better prognosis that most likely does not require intensive therapy. De-escalation of therapy in case of HPV-associated tumor is a matter of current studies.
Arthroscopic Treatment of a Low-Velocity Gunshot Injury to a Primary Total Hip Arthroplasty
Authors: Fournier Matthew N. , Rider Carson M. , Olinger Catherine R. , Dabov Gregory D. , Mihalko William M. , Mihalko Marc J. 
Published: March 2019

Case:
An immunosuppressed 51-year-old man sustained a ballistic injury about the site of a primary total hip arthroplasty, which had been performed for osteonecrosis of the femoral head 2 years earlier. He was treated with arthroscopic debridement and irrigation, inspection of the implants, and removal of foreign bodies.

Conclusion:
Ballistic injury to a hip arthroplasty site with retained foreign bodies is an unusual injury. Hip arthroscopy may represent a minimally invasive treatment option for implant inspection, joint debridement, and removal of intra-articular fragments while minimizing the risk of soft-tissue complications.
When Stars Do Not Align: Overall Hospital Quality Star Ratings and the Volume-Outcome Association
Authors: Fontana Mark Alan , Lyman Stephen , Islam Wasif , MacLean Catherine H. 
Published: March 2019

Background:
Volume-outcome relationships are well established for coronary artery bypass grafting and total joint arthroplasty surgery. Although the U.S. Centers for Medicare & Medicaid Services (CMS) Overall Hospital Quality Star Ratings program includes outcome quality measures for these procedures, these outcome quality measures are not counted toward the star ratings for low-volume hospitals. We sought to assess whether excluding low-volume hospitals from surgical quality measures with known volume-outcome relationships affects the star ratings.

Methods:
We identified quality measures used in CMS’s star ratings that are related to surgical procedures with a known volume-outcome relationship and tested for the presence of the volume-outcome association for each of these measures. We then imputed missing values for low-volume hospitals for each measure and otherwise identically repeated the CMS calculations in order to assess the percentages of hospitals with the same, better, or worse ratings.

Results:
Among the measures used to calculate star ratings, we identified 4 quality measures (2 related to coronary artery bypass grafting and 2 related to total joint arthroplasty) with known volume-outcome relationships that were excluded from the calculations of the star ratings for low-volume hospitals. We confirmed a volume-outcome association in the CMS data for all 4 measures. When total joint arthroplasty complications were imputed for low-volume hospitals and then included in the calculation of the star ratings, over one-third of hospitals received a different rating; both low-volume and other hospitals were more often hurt than helped. Imputing the other 3 quality measures among low-volume hospitals left the ratings unchanged.

Conclusions:
The CMS star ratings do not fully represent the risks of undergoing procedures at low-volume hospitals, potentially misrepresent quality across facilities, and hence are of uncertain utility to consumers.
Estudo retrospectivo dos diagnósticos de tristeza parasitária bovina no Oeste Catarinense
Authors: Mendes Ricardo Evandro , Gris Anderson , Henker Luan Cleber , Christ Ricardo , Piva Manoela Marchezan , Schwertz Claiton Ismael , Lucca Neuber José , Broll Fabrisio , Medeiros Diovane dos Santos , Pozzo Ildo Dal , Mori Ademar Masaaki 
Published: March 2019

A Tristeza Parasitária Bovina (TPB) é um complexo de doenças causado pelas rickettsias Anaplasma marginale e/ou A. centrale, bem como pelos protozoários Babesia bovis e/ou B. bigemina, os quais produzem um quadro de anemia severa. Este trabalho tem por objetivo relatar a ocorrência da enfermidade no Oeste Catarinense, diagnosticada pelo Laboratório de Patologia Veterinária do IFC - Campus Concórdia. Para tanto, realizou-se um estudo retrospectivo dos diagnósticos em bovinos entre 2013 e 2015. No período estudado a anaplasmose representou 56% (9/17), babesiose cerebral 33% (6/17) e babesiose 11% (2/17). A partir dos dados coletados observou-se um nítido aumento consecutivo do número de casos de TPB nos três anos estudados. Conjectura-se que as alterações climáticas recentes ocasionadas pelos invernos menos rigorosos estejam contribuindo para este incremento. Além disso, os médicos veterinários que atenderam os animais relataram que o curso clínico da enfermidade está apresentando-se de modo mais agudo e severo em comparação aos anos anteriores, podendo isso estar relacionado ao método de manejo dos animais jovens utilizado na região. Conclui-se que a TPB é uma importante causa de mortalidade em bovinos na região e que a ocorrência daenfermidade vem aumentando.Palavras-chave: Patologia, babesiose, anaplasmose, bovinocultura.
Myasthenic crisis treated in a Chinese neurological intensive care unit: clinical features, mortality, outcomes, and predictors of survival
Authors: Liu Fan , Wang Qiong , Chen Xueping 
Published: March 2019

Abstract
Background

Myasthenic crisis (MC) often requires admission to an intensive care unit (ICU).

Methods

We retrospectively investigated 115 consecutive patients with first MC admitted to the neurological ICU. Patients’ demographic, clinical and other characteristics were examined, as well as therapeutic interventions; mortality and functional outcome.

Results

MC patients admitted to neurological ICU had a mortality rate of 24.34%. PCO2 level before intubation and score on Myasthenia Gravis–Activities of Daily Living (MG-ADL) scale at MC onset correlated with duration of ventilation and length of ICU stay. Compared with patients with good functional outcome, patients with intermediate or poor functional outcome were older at first MC onset, had lower pH and PO2, and had higher PCO2 before intubation. Multivariate logistic analysis identified pre-intubation PCO2 level as an independent predictor of survival. Cox regression showed that age at first MC onset requiring ICU management was the factor which significantly influenced the mortality. Conclusions: Our results suggest that PCO2 before intubation and MG-ADL score at MC onset may be useful indicators of more severe disease likely to require extensive respiratory support and ICU management. Higher pre-intubation PCO2 indicates chronic respiratory acidosis that can increase risk of severe disability and death, especially in patients with older age at first MC onset.