bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation and characterization of modified polyphenylsulfone membranes with hydrophilic property for filtration of aqueous media
Authors: Kiani Shirin , Mousavi Seyed Mahmoud , Saljoughi Ehsan , Shahtahmassebi Nasser 
Published: March 2018

In the present research, the low water flux of polyphenylsulfone membranes was addressed, and a novel improvement in their water permeation and fouling resistance was achieved using polyethylene glycol (PEG) as the hydrophilic additive. Scanning electron microscopy and field emission scanning electron microscopy, atomic force microscopy, attenuated total reflection Fourier‐transform infrared spectroscopy, thermogravimetric analysis, and tensile test were applied for the investigation of membrane morphology, surface topography, surface chemical structure, thermal stability, and mechanical properties, respectively. Moreover, the relative hydrophilicity/hydrophobicity of the membranes was assessed via determination of membrane water uptake capacity and water contact angle. The membrane performance was studied and compared by determination of pure water flux and filtration of canned beans production wastewater as well as bovine serum albumin solution. The filtration results indicated a remarkable pure water flux and 100% turbidity rejection provided by the polyphenylsulfone/PEG 20 000 membrane. In addition, it was confirmed that the amount of residual PEG within the membrane was increased with increasing PEG molecular weight and concentration.
Facile preparation of multifunctional poly(amide‐imide)/polyaniline films: Combining self‐cleaning, self‐extinguishing, and conductive
Authors: Wang Yanbin , Wang Teng , Wang Tingmu , Zhang Jinyi , Chen Jinxing , Yang Rui , Ruan Linxiao , Wang Biaobing 
Published: March 2018

Recently, multifunctional films are of particular interest to scientists owing to their diversified properties. Here, we demonstrated that self‐cleaning, self‐extinguishing, and high conductive films were fabricated by simple solvent‐casting method from poly(amide‐imide)/polyaniline composites. The multifunctional films exhibited controllable water contact angles varying from 65° to 120° and high electrical conductivities of over 40 S m−1. Moreover, due to the improved hydrophobicity, the multifunctional films showed self‐cleaning characteristics and were used to collect the dust powders easily and perfectly during the dispensed water droplet rolling off the solid surface. Furthermore, the self‐extinguishing property of the multifunctional films was confirmed by thermogravimetric analysis. The special film composition and morphology are the two important aspects that induce such unusual properties. The polyaniline content can strongly influence the morphology of the composite films, which in turn display different hydrophobicities and conductivities. POLYM. ENG. SCI., 59:E33–E43, 2019. © 2018 Society of Plastics Engineers
Preparation of monodispersed ZrO2 nanoparticles and their applications in poly[(vinylidene fluoride)‐co‐hexafluoropropylene]‐based composite polymer electrolytes
Authors: Wang Zhiyan , Miao Chang , Zhang Yan , Fang Rui , Yan Xuemin , Jiang Yu , Tian Minglei , Xiao Wei 
Published: March 2018

AbstractTo improve the electrochemical performance of pure poly[(vinylidene fluoride)‐co‐hexafluoropropylene] (P(VDF‐HFP))‐based gel polymer electrolytes, different amounts of monodispersed ZrO2 nanoparticles were introduced to fabricate P(VDF‐HFP)/ZrO2 composite polymer electrolytes (CPEs) using the phase inversion method and activated processes, in which the monodispersed ZrO2 nanoparticles were synthesized by an easy route without any chelating agents or surfactants, and confirmed using scanning electron microscopy, particle size distribution measurement and X‐ray diffraction. The characterization results show that the as‐fabricated CPE membranes present not only an abundant porous structure, but also an improved mechanical strength. In particular, sample CPE‐5 presents the best properties when the doped content of the monodispersed ZrO2 nanoparticles reaches 5 wt% in the polymer matrix, in which the liquid uptake and ionic conductivity at room temperature are about 192.4% and 3.926 mS cm−1, and the electrochemical working window and thermal decomposition temperature can increase to 5.1 V and 420 °C, respectively. Moreover, an assembled LiCoO2/CPE‐5/Li coin cell can deliver excellent rate and cycling performance, in which the discharge specific capacity of the cell can show about 83.95% capacity retention at 2.0 C after 85 cycles. © 2018 Society of Chemical Industry
Psychological impact of multigene cancer panel testing in patients with a clinical suspicion of hereditary cancer across Spain
Authors: Esteban I. , Vilaró M. , Adrover E. , Angulo A. , Carrasco E. , Gadea N. , Sánchez A. , Ocaña T. , Llort G. , Jover R. , Cubiella J. , Servitja S. , Herráiz M. , Cid L. , Martínez S. , Oruezábal‐Moreno M.J. , Garau I. , Khorrami S. , Herreros‐de‐Tejada A. , Morales R. , Cano J.M. , Serrano R. , López‐Ceballos M.H. , González‐Santiago S. , Juan‐Fita M.J. , Alonso‐Cerezo C. , Casas A. , Graña B. , Teulé A. , Alba E. , Antón A. , Guillén‐Ponce C. , Sánchez‐Heras A.B. , Alés‐Martínez J.E. , Brunet J. , Balaguer F. , Balmaña J. 
Published: March 2018

AbstractObjectivePatients' psychological reactions to multigene cancer panel testing might differ compared with the single‐gene testing reactions because of the complexity and uncertainty associated with the different possible results. Understanding patients' preferences and psychological impact of multigene panel testing is important to adapt the genetic counselling model.MethodsOne hundred eighty‐seven unrelated patients with clinical suspicion of hereditary cancer undergoing a 25‐gene panel test completed questionnaires after pretest genetic counselling and at 1 week, 3 months, and 12 months after results to elicit their preferences regarding results disclosure and to measure their cancer worry and testing‐specific distress and uncertainty.ResultsA pathogenic variant was identified in 38 patients (34 high penetrance and 4 moderate penetrance variants), and 54 patients had at least one variant of uncertain significance. Overall, cancer panel testing was not associated with an increase in cancer worry after results disclosure (P value = .87). Twelve months after results, carriers of a moderate penetrance variant had higher distress and uncertainty scores compared with carriers of high penetrance variants. Cancer worry prior to genetic testing predicted genetic testing specific distress after results, especially at long term (P value <.001). Most of the patients reported the wish to know all genetic results.ConclusionsOur results suggest that patients can psychologically cope with cancer panel testing, but distress and uncertainty observed in carriers of moderate penetrance cancer variants in this cohort warrant further research.
Interfraction movement and clinical outcome of immobilization for thoracic irradiation: A randomized controlled trial
Authors: Pulvirenti Trish , Agustin Cherry , Tamas Monica , Harris Jillian , Verning Maria , Cross Shamira , Jayamohan Jayasingham , Yeghiaian‐Alvandi Roland , Gebski Val 
Published: March 2018

AbstractObjectiveTo evaluate the impact of immobilization on set‐up errors and clinical outcomes in patients receiving radiation therapy to the thorax.MethodsPatients receiving curative intent radiation therapy to the lung and esophagus were randomized to no immobilization (control) or immobilization (chest jig or vacuum bag), and treatment verification images were acquired within 3 days of commencing treatment and then weekly. The primary outcome was the proportion of patients having a deviation >5 mm from the isocenter. Assessment was carried out blinded to immobilization assignment.ResultsOf the 77 patients, 75 patients were allocated to either immobilization or control. No statistical difference in the proportion of patients with bony displacements >5 mm from the isocenter were observed (P = 0.5), as was the case for both systematic and random errors between the groups. There was an increased risk of local failure in the immobilized control group (HR 1.46, 95% CI 0.78–2.71, P = 0.23) based on a competing risk analysis. The median overall survival was 18.4 months and 27.0 months in the control and immobilized groups, respectively (HR 0.73, 95% CI 0.51–1.04, P = 0.08).ConclusionsThe results failed to show benefit with immobilization in reducing set‐up errors, local control, and overall survival.
RNA expression profiling in sulfamethoxazole‐treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes
Authors: Reinhart Jennifer M. , Rose Warren , Panyard Daniel J. , Newton Michael A. , Liebenstein Tyler K. , Yee Jeremiah , Trepanier Lauren A. 
Published: March 2018

AbstractThe lymphocyte toxicity assay (LTA) is a proposed surrogate marker of sulfonamide antibiotic hypersensitivity. In theLTA, peripheral blood mononuclear cells (PBMCs) undergo apoptosis more readily in hypersensitive versus tolerant patients when exposed to drug‐hydroxylamine metabolites in vitro. The purpose of this study was to identify key gene transcripts associated with increased cytotoxicity from sulfamethoxazole‐hydroxylamine in humanPBMCs in theLTA. TheLTAwas performed onPBMCs of 10 patients hypersensitive to trimethoprim‐sulfamethoxazole (HS) and 10 drug‐tolerant controls (TOL), using two cytotoxicity assays:YO‐PRO(n = 20) andMTT(n = 12).mRNAexpression profiles ofPBMCs, enriched forCD8+T cells, were compared betweenHSandTOLpatients. Transcript expression was interrogated for correlation with % cytotoxicity fromYO‐PROandMTTassays. Correlated transcripts of interest were validated byqPCR.LTAresults were not significantly different betweenHSandTOLpatients, and no transcripts were found to be differentially expressed between the two groups. 96 transcripts were correlated with cytotoxicity byYO‐PRO(r = ±.63‐.75,FDR0.188). Transcripts were selected for validation based on mechanistic plausibility and three were significantly over‐expressed byqPCRin high cytotoxicity patients: multi‐specific organic anion transporter C (ABCC5), mitoferrin‐1 (SLC25A37), and Porimin (TMEM123). These data identify novel transcripts that could contribute to sulfonamide‐hydroxylamine induced cytotoxicity. These includeSLC25A37, encoding a mitochondrial iron transporter,ABCC5, encoding an arylamine drug transporter, andTMEM123, encoding a transmembrane protein that mediates cell death.
Pesticide durability and the evolution of resistance: A novel application of survival analysis
Authors: Brevik Kristian , Schoville Sean D , Mota‐Sanchez David , Chen Yolanda H 
Published: March 2018

AbstractBACKGROUNDArthropod pests are widely perceived to evolve resistance to insecticides at different rates. Although widespread “successful” species are assumed to evolve quickly and minor pests slowly, few studies have utilized published data on resistance events to test for differences among species. Using 532 records from the Arthropod Pesticide Resistance Database covering 20 species, we applied a survival analysis to model the number of generations from insecticide introduction to the first report of arthropod resistance, providing one of the most comprehensive analyses of this question to date. Our approach tested: 1) whether successful pests evolve resistance faster than close relatives, 2) whether species differ significantly in the time to demonstrate resistance, and 3) whether different insecticide classes differ in durability (length of time an insecticide is used before resistance arises).RESULTSWe found that species differed significantly in the amount of time it took for resistance to be reported. Overall, the median duration between the introduction of an insecticide and the first report of resistance was 66 generations (95% c.i. 60‐78 generations), and highly‐resistant arthropods did not evolve resistance faster than their relatives. Insecticide durability did not differ by the mode of action or year of introduction.CONCLUSIONArthropod species significantly varied in how rapidly they evolve resistance to new insecticides, regardless of their chemistry. Visualization of the history of insecticide resistance provides information to be used for understanding how pesticide resistance evolved and how it can best be managed. © 2018 Society of Chemical Industry
Terrestrial primary production for the conterminous United States derived from Landsat 30 m and MODIS 250 m
Authors: Robinson Nathaniel P. , Allred Brady W. , Smith William K. , Jones Matthew O. , Moreno Alvaro , Erickson Tyler A. , Naugle David E. , Running Steven W. 
Published: March 2018

AbstractTerrestrial primary production is a fundamental ecological process and a crucial component in understanding the flow of energy through trophic levels. The global MODIS gross primary production (GPP) and net primary production (NPP) products (MOD17) are widely used for monitoring GPP and NPP at coarse resolutions across broad spatial extents. The coarse input datasets and global biome‐level parameters, however, are well‐known limitations to the applicability of the MOD17 product at finer scales. We addressed these limitations and created two improved products for the conterminous United States (CONUS) that capture the spatiotemporal variability in terrestrial production. The MOD17 algorithm was utilized with medium resolution land cover classifications and improved meteorological data specific to CONUS in order to produce: (a) Landsat derived 16‐day GPP and annual NPP at 30 m resolution from 1986 to 2016 (GPPL30 and NPPL30, respectively); and (b) MODIS derived 8‐day GPP and annual NPP at 250 m resolution from 2001 to 2016 (GPPM250 and NPPM250 respectively). Biome‐specific input parameters were optimized based on eddy covariance flux tower‐derived GPP data from the FLUXNET2015 database. We evaluated GPPL30 and GPPM250 products against the standard MODIS GPP product utilizing a select subset of representative flux tower sites, and found improvement across all land cover classes except croplands. We also found consistent interannual variability and trends across NPPL30, NPPM250, and the standard MODIS NPP product. We highlight the application potential of the production products, demonstrating their improved capacity for monitoring terrestrial production at higher levels of spatial detail across broad spatiotemporal scales.
Damage accumulation and structural modification in a‐ and c‐plane GaN implanted with 400‐keV and 5‐MeV Au+ ions
Authors: Macková A. , Malinskyˊ P. , Jágerová A. , Sofer Z. , Sedmidubský D. , Klímová K. , Böttger R. , Akhmadaliev S. 
Published: March 2018

c‐plane (0001) and a‐plane (11‐20) gallium nitride (GaN) epitaxial layers were grown by Metal organic Vapour Phase epitaxy (MOVPE) on sapphire and subsequently implanted with 400‐keV and 5‐MeV Au+ ions using fluences 5 × 1014 to 5 × 1015 cm−2. The shallow Au depth profiling was accomplished by Rutherford backscattering spectrometry. The structural changes during implantation and subsequent annealing were characterised by Rutherford backscattering spectrometry channelling and Raman spectroscopy. The interplay between nuclear and electronic stopping, influencing defect accumulation, was monitored and discussed depending on GaN orientation. Post‐implantation annealing induced a structural reorganisation of the GaN structure depending on the ion‐implantation fluence, ion energy, and on the crystallographic orientation.
Iodine‐Catalyzed Synthesis of Pyrrolo(2,3‐c)coumarin Derivatives Using 3‐Aminocoumarins, Arylglyoxals and 4‐Hydroxycoumarin through One‐Pot Three‐Component Reaction
Authors: Belal Md. , Khan Abu T. 
Published: March 2018

AbstractSynthesis of pyrrolo(2,3‐c)coumarin derivatives was achieved from 3‐aminocoumarins, arylglyoxals and 4‐hydroxycoumarin using 20 mol% molecular iodine as a catalyst through one‐pot three‐component reaction. The products were isolated without aqueous work‐up or column chromatography in good yields. The present protocol is an efficient synthetic route to access various substituted pyrrolo(2,3‐c)coumarin derivatives in large scale.
β‐Functionalized Imidazole‐Fused Porphyrin‐Donor‐Based Dyes: Effect of π‐Linker and Acceptor on Optoelectronic and Photovoltaic Properties
Authors: Bodedla Govardhana Babu , Wang Hongda , Chang Shuai , Chen Song , Chen Tao , Zhao Jianzhang , Wong Wai‐Kwok , Zhu Xunjin 
Published: March 2018

AbstractWe have designed and synthesized three new donor (D)‐linker (π)‐acceptor (A) type β‐functionalized imidazole‐fused porphyrins, 4 a‐4 c by grafting the acceptor such as cyanoacrylic acid/carboxylic acid at 2nd position of imidazole fused to the β,β′ edge of porphyrin donor via π‐linker such as thiophene/phenylene and examined them as sensitizers for dye‐sensitized solar cells (DSSCs). The structure‐activity relationships of the dyes are systematically investigated by using absorption spectroscopy, cyclic voltammetry, and density functional theory calculations. Dyes, 4 a and 4 b possessing cyanoacrylic acid acceptor exhibited broadened Soret bands compared with that of dye 4 c containing carboxylic acid acceptor, which led to good light‐harvesting properties and thereby broader IPCE curves. The DSSCs of the dye, 4 a possessing thiophene linker and cyanoacrylic acid acceptor exhibit higher power conversion efficiency than the analogous dyes, 4 b and 4 c with phenylene π‐linker and cyanoacrylic acid or carboxylic acid acceptor. The hike in the efficiency comes from the increased short‐circuit current and open‐circuit voltage due to reduced dye aggregation. Electrochemical impedance spectroscopy studies reveal that the life‐time of the injected electrons in the conduction band of TiO2 and charge recombination rate at the TiO2/dye/electrolyte interface mainly dependent on nature of π‐linker and acceptor of the dyes.
Conductive Ag‐Based Modification of Hydroxyapatite Microtubule Array and Its Application to Enzyme‐Free Glucose Sensing
Authors: Jiang Yingying , Liu Haiyan , Qi Xuan , Sun Jun , Li Mei , Wang Jun 
Published: March 2018

AbstractPlenty of biomineralized hydroxyapatite (BioHAP) matrix microtubules (named dentin tubules) with regular arrangement are inside mammal tooth dentin. Herein, electrically conductive polyaniline (PANI) is applied to modify the microtubule array to assemble a PANI/BioHAP composite through an in‐situ polymerization method. On this basis, a sensor (PANI/BioHAP/AgHg) is assembled with PANI/BioHAP and silver amalgam, and further applied to enzyme‐free glucose sensing. The inner‐wall of the tubules is treated in advance with p‐methylbenzene sulfonic acid to alter its hydrophilism into hydrophobicity. The treatment contributes to improve the diffusibility of aniline monomer in the tubules and to form a PANI conductive network on the wall. Meanwhile, a large quantity of active sites on the surface of BioHAP matrix performs both adsorption and concentration to glucose molecules. The special array structure helps to shield undesired electrochemical signals, and also increases the current response of glucose electro‐catalytic oxidation.
Hydrophobic Hydrolytic‐Stable N‐Alkylimidazole‐Cyanoborane Complexes as Ultrafast‐Igniting Hypergolic Fuels
Authors: Li Xingye , Lu Tian , Nan Jiayu , Li Haibo , Nie Fude , Zhang Yan‐Qiang , Chen Fu‐Xue 
Published: March 2018

AbstractIntroduction of cyano group into the molecules of borane‐based hypergolic fuels can greatly reinforce the hydrolytic stability. By the formation of complex between BH2CN and imidazole, six complexes were readily prepared from N‐alkyl substituted imidazole hydrochloride salts and NaBH3CN in THF and fully characterized by 1H and 13C NMR, IR spectroscopy, high‐resolution mass spectrum, and differential scanning calorimetry (DSC). Among them, 1‐allylimidazole‐cyanoborane complex (5) displayed some attractive properties such as water immiscibility and good hydrolytic stability, high density (>1.0 g cm−3), good thermal stability (Td, 193 °C, onset), high calculated density impulse (ρIsp, 358 s g cm−3), ultra‐short ignition delay time (WFNA, 3 ms), and super low viscosity (8.4 mPa s), showing the real application potential as a fuel and an efficient fuel additive in bipropellants.
Promiscuity of Lipase‐Catalyzed Reactions for Organic Synthesis: A Recent Update
Authors: Dwivedee Bharat P. , Soni Surbhi , Sharma Misha , Bhaumik Jayeeta , Laha Joydev K. , Banerjee Uttam C. 
Published: March 2018

AbstractLipase‐catalyzed organic reactions have widely been practiced in the past three decades. In addition to its wide acceptance in conventional reactions such as hydrolysis, transesterification, and enantiopure synthesis (kinetic resolution and dynamic kinetic resolution) several reports on the catalytic promiscuity of lipases have also been published. The concept of promiscuity, where lipase catalyzes reactions beyond its natural function, has been perceived as a useful phenomenon which can enhance the utility of lipase as a biocatalyst. Many useful organic reactions such as Aldol condensation, Hantzsch reaction, Canizzaro reaction, Mannich reaction, Baylis‐Hillman reaction, Knoevenagel condensation, Michael addition, Ugi reaction, and oxidation catalyzed by lipases have surfaced in the literature. The current review is a critical compilation of such research findings to put forth the synthetic applications of lipase, beyond the orthodox biocatalytic toolbox.
1,2,3,4,6‐Penta‐O‐galloyl‐β‐D‐glucopyranose: Its Anti‐Inflammatory and Antibacterial Properties
Authors: Bobrowska Diana M. , Czyrko Justyna , Eljaszewicz Andrzej , Grubczak Kamil , Wlodarczyk Anna J. , Moniuszko Marcin , Brzezinski Krzysztof , Plonska‐Brzezinska Marta E. 
Published: March 2018

AbstractOne of the polyphenolic compounds with strong antioxidant and antibacterial activities is 1,2,3,4,6‐penta‐O‐galloyl‐D‐glucopyranose (PGG). Herein, we analysed the influence of PGG on mammalian and bacterial cells, including human umbilical vascular endothelial cells (HUVECs), monocytes and a strain of Pseudomonas aeruginosa. Additionally, our results demonstrate the anti‐inflammatory potential of 1,2,3,4,6‐penta‐O‐galloyl‐β‐D‐glucopyranose (β‐PGG) in monocytes via the modulation of cell activity. Our study also indicates a high activity of β‐PGG against the quality control strain of Pseudomonas aeruginosa. Similar experiments were performed using gallic acid (GA), and the results indicated that this PGG metabolite does not reveals the biological properties of the glycoside.
Aerobic Oxidation of Thiols to Disulfides by Silver‐Based Magnetic Catalyst
Authors: Gaur Rashmi , Yadav Manavi , Gupta Radhika , Arora Gunjan , Rana Pooja , Sharma Rakesh K. 
Published: March 2018

AbstractIn the present report, we have synthesized and characterized a magnetically retrievable, easily generated, chemically stable, and environmental friendly silver based nanocatalyst for the oxidation of thiols. The obtained heterogeneous catalyst was thoroughly characterized by various techniques including X‐ray diffraction studies, Fourier transform‐infrared spectroscopy, Transmission electron microscopy, Field emission‐ scanning electron microscopy analysis, Vibrating sample magnetometric analysis, inductively coupled plasma‐optical emission spectrometer and dispersive spectroscopic analysis. Excellent yield of disulfides can be easily obtained from corresponding thiols within 30 min through simple stirring in water at room temperature under aerobic condition. Further, this protocol involves low loading of silver and undergoes no leaching. Moreover, it also circumvents the use of harsh and expensive oxidising agents and bases. Additionally, superb catalytic activity, effortless catalytic recovery and recyclability of the catalyst upto seven consecutive runs without significant loss of activity, make the present protocol highly sustainable to deal with industrial needs as well as environmental and biological concerns.