bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment With Grazoprevir/Elbasvir for Renal Transplant Recipients With Chronic Hepatitis C Virus Infection and Impaired Allograft Function
Authors: Eisenberger Ute , Friebus-Kardash Justa , Guberina Hana , Kribben Andreas , Witzke Oliver , Willuweit Katharina , Gerken Guido , Herzer Kerstin 
Published: January 2019

Background
Direct-acing antiviral agents are highly efficient treatment options for chronic hepatitis C virus (HCV) infection after renal allograft transplantation. Treatment options for patients with impaired graft function remain limited. Therefore, we assessed the effectiveness and safety of grazoprevir/elbasvir therapy for patients with chronic HCV infection and impaired renal allograft function.

Methods
Eleven renal allograft recipients with therapy-naïve HCV genotype (GT) 1a, 1b, or 4 were treated with the fixed-dose combination of elbasvir/grazoprevir without ribavirin for 12 weeks. All recipients exhibited impaired graft function with an average glomerular filtration rate lower than 30 mL/min per 1.73 m2. Clinical data were retrospectively reviewed for renal and liver function parameters. Patients were closely monitored for trough levels of immunosuppressive agents, viral load, laboratory values, and potential adverse effects.

Results
Seven (64%) patients exhibited a rapid virologic response within 4 weeks (HCV GT1a, n = 2; HCV GT1b, n = 5). The other 4 patients exhibited a virologic response within 8 weeks (HCV GT1b, n = 3; HCV GT 4, n = 1). All patients exhibited a sustained virologic response at week 12 after the end of treatment. Clinical measures of liver function improved substantially for all patients. Few adverse effects were reported. Impaired renal allograft function and proteinuria remained stable. For most patients, only moderate adjustments to the tacrolimus dosage were necessary for maintaining sufficient trough levels.

Conclusions
This treatment appears to be safe and effective for renal transplant recipients with impaired allograft function and is a promising treatment option for eradicating HCV infection in this patient population.
Ostomy Adjustment Inventory-23 (OAI-23)
Authors: Dellafiore Federica , Conte Gianluca , Baroni Irene , Pittella Francesco , Di Pasquale Cristina , Nania Tiziana , Saracco Carla , Roveron Gabriele , Caruso Rosario 
Published: January 2019

PURPOSE:
The purpose of this study was to evaluate the validity and reliability of the Italian version of the Ostomy Adjustment Inventory-23 (OAI-23).

DESIGN:
This is a methodological study evaluated psychometric properties of the OAI-23.

SUBJECTS AND SETTING:
A sample of 230 patients with an ostomy was enrolled in an Italian university hospital from May to September 2017.

METHODS:
This study comprised two phases; during phase 1, the cultural-linguistic translation of the OAI-23 into Italian was completed. In addition, content and face validity were tested. In phase 2, psychometric testing of the OAI-23 was conducted in a cross-section sample of 258 Italian patients with a fecal ostomy.

RESULTS:
The Italian version of the OAI-23 presents 23 items giving a 3-dimensional structure: acceptance, negative feelings, and social engagement. Accordingly, this 3-dimensional structure arise from an exploratory factorial analysis with the maximum likelihood robust estimator (RMSEA = 0.089 [95% CI = 0.063-0.113; P = .05], and CFI = 0.901, explaining 44% of the total variance). The internal consistency of the OAI-23 was good (Cronbach α for acceptance = 0.91; for negative feelings = 0.87; for social engagement = 0.93; for overall scale = 0.91).

CONCLUSIONS:
The OAI-23 provides a valid and reliable assessment of patients' psychosocial adjustment to an ostomy. It provides important resource for clinical decision-making; for example, it may be used to design or tailor educational strategies to enhance psychosocial adjustment following creation of an ostomy.
Pressure Redistribution Crib Mattress
Authors: Singh Charleen Deo , Shoqirat Noordeen 
Published: January 2019

BACKGROUND:
Selective use of pressure-redistributing support surfaces is considered an essential component of a pressure injury prevention bundle. Critically ill children who are too big for an isolette but too little for a bed are usually placed in critical care cribs that have unique features such as moveable side rails and a built-in scale for weighing the patient, but they do not have a mattress designed to redistribute pressure. The primary aim of this quality improvement project was to evaluate a pressure redistribution mattress designed for use in critical care cribs.

CASES:
We retrospectively reviewed 22 charts of critically ill pediatric patients who participated in a product trial completed over a 12-week period in a stand-alone children's hospital in the Western United States. We reviewed demographic data, skin assessments, Braden Q Scale score, and support surface use. Our review revealed no pressure injury occurrences over the 12-week data collection period.

CONCLUSIONS:
Findings from this quality improvement project suggest that the pressure-redistributing mattress, when used as part of an intervention bundle, prevents pressure injuries in critically ill pediatric patients.
Fibre Bragg grating sensor applications for structural health monitoring
Authors: Karatas Cansu , Degerliyurt Boray , Yaman Yavuz , Sahin Melin 
Published: January 2019

Purpose
Structural health monitoring (SHM) has become an attractive subject in aerospace engineering field considering the opportunity to avoid catastrophic failures by detecting damage in advance and to reduce maintenance costs. Fibre Bragg Grating (FBG) sensors are denoted as one of the most promising sensors for SHM applications as they are lightweight, immune to electromagnetic effects and able to be embedded between the layers of composite structures. The purpose of this paper is to research on and demonstrate the feasibility of FBG sensors for SHM of composite structures.

Design/methodology/approach
Applications on thin composite beams intended for SHM studies are presented. The sensor system, which includes FBG sensors and related interrogator system, and manufacturing of the beams with embedded sensors, are detailed. Static tension and torsion tests are conducted to verify the effectiveness of the system. Strain analysis results obtained from the tests are compared with the ones obtained from the finite element analyses conducted using ABAQUS® software. In addition, the comparison between the data obtained from the FBG sensors and from the strain gauges is made by also considering the noise content. Finally, fatigue test under torsion load is conducted to observe the durability of FBG sensors.

Findings
The results demonstrated that FBG sensors are feasible for SHM of composite structures as the strain data are accurate and less noisy compared to that obtained from the strain gauges. Furthermore, the convenience of obtaining reliable data between the layers of a composite structure using embedded FBG sensors is observed.

Practical implications
Observing the advantages of the FBG sensors for strain measurement will promote using FBG sensors for damage detection related to the SHM applications.

Originality/value
This paper presents applications of FBG sensors on thin composite beams, which reveal the suitability of FBG sensors for SHM of lightweight composite structures.
Lesson study as a trigger for preservice physics and chemistry teachers’ learning about inquiry tasks and classroom communication
Authors: Conceição Teresa , Baptista Mónica , da Ponte João Pedro 
Published: January 2019

PurposeThe purpose of this paper is to understand what physics and chemistry preservice teachers learn on the nature of the inquiry tasks and about classroom communication in an inquiry task when they take part in a lesson study.Design/methodology/approachThis is a qualitative and interpretive research which was carried out within a master’s degree course in physics and chemistry teaching with three preservice teachers. Data were collected from participant observation with video recording, interviews, written reflections and group report by the preservice teachers. This two-cycle lesson study was conducted over 12 sessions. The data analysis took place through asking questions and using the constant comparison method, which allowed the identification of the most relevant issues about the preservice teachers learning according to the categories nature of the inquiry tasks and communication promoted by the teacher.FindingsThe results show that the preservice teachers learnt to identify the characteristics of inquiry tasks, how to develop an inquiry task when planning the research lesson and acknowledged its potential for student learning. Moreover, the preservice teachers acknowledged the fact that the classroom communication promoted by the teacher fostered student participation, negotiation of meanings about scientific concepts and construction of new learning that can be shared within the class.Research limitations/implicationsResearch is needed as regards how initial teacher education providers may contribute to the learning of preservice teachers in lesson study in initial teacher education programmes.Originality/valueThis research contributes to show potentialities of lesson study in the initial teacher education of preservice physics and chemistry teachers.
Employee engagement and job performance in Lebanon: the mediating role of creativity
Authors: Ismail Hussein Nabil , Iqbal Adnan , Nasr Lina 
Published: January 2019

PurposeThe purpose of this paper is to explore the relationship between employee engagement and job performance in the country of Lebanon, and to test whether creativity mediates the relationship between engagement and performance.Design/methodology/approachThe research sample consisted of 186 respondents working in Lebanese firms. The questionnaire included established measures relating to employee engagement, job performance and creativity – in addition to various demographic questions. Stepwise multiple regression and bootstrapping methods were employed in the analysis of the data.FindingsThe findings showed a significant positive effect of employee engagement on job performance. However, mediation analysis using bootstrapping methods has shown that creativity has fully mediated the relationship between engagement and performance.Originality/valueThe study extends previous research and increases the external validity of the findings by investigating the relationship between engagement and performance in new non-western contexts. Moreover, this is one of the first research studies that explores the role of creativity in the relationship between the two variables; this helps in improving our understanding of the model and aids in enhancing the effect of engagement on performance.
Reinterpreting the value chain in an indigenous community enterprise context
Authors: Kawharu Merata 
Published: January 2019

Purpose
Research in the field of indigenous value chains is limited in theory and empirical research. The purpose of this paper is to interpret values that may inform a new approach to considering value chains from New Zealand Maori kin community contexts.

Design/methodology/approach
The paper derives from research that develops Indigenous research methods on positionality. By extending the “included researcher” (Kawharu, 2016) role, the research recognises the opportunity of being genealogically connected to one of the communities, which may enable “deep dive research” relatively easily. Yet practical implications of research also obligate researchers beyond contractual terms to fulfil community aspirations in innovation.

Findings
Research findings show that a kin community micro-economy value chain may not be a lineal, progressive sequence of value from supplier to consumer as in Porter’s (1985) conceptualisation of value chains, but may instead be a cyclical system and highly consumer-driven. Research shows that there is strong community desire to connect lands and resources of homelands with descendant consumers wherever they live and reconnect consumers back again to supply sources. Mechanisms enabling this chain include returning food scraps to small community suppliers for composting, or consumers participating in community working bees, harvesting days and the like.

Social implications
The model may have implications and applicability internationally among indigenous communities who are similarly interested in socio-economic growth and enterprise development.

Originality/value
The apper’s originality, therefore, derives from addressing a research gap, showing that indigenous values may provide a new approach to conceptualising value chains and developing them in practice.
Stress analysis of shielding electrode in chip with pressure sensor embedded in accelerometer
Authors: Lu Chun-Lin , Yeh Meng-Kao 
Published: January 2019

Purpose
Analysis of the thermal effects during the packaging process or in the actual operating environment is necessary to develop small monolithic integrated sensing chips with heterogeneous integration. The use of multiple layers and various materials in monolithic integrated sensing chips addresses the coefficient of thermal expansion (CTE) mismatch issue. The purpose of this study is to focus on the residual stress analysis of the shielding electrode, which is a metal film that prevents pull-in of proof-mass during anodic bonding in microelectromechanical system (MEMS) chips with pressure sensors embedded in an accelerometer.

Design/methodology/approach
The finite element model of the chip was built by the commercial software ANSYS, and the residual stress was evaluated during the die attachment process for the shielding electrode. Various shielding electrode materials and a proposed design with a keep-out zone to reduce the residual stress are discussed, with a focus on the relationship between the geometric parameters of the chip and the residual stress for copper shielding electrodes of different thicknesses.

Findings
The results of the finite element analysis showed that the use of polysilicon as a shielding electrode in the proposed design generated the lowest residual stress because of its low CTE. The maximum stresses in both of in-plane and out-of-plane directions in the finite element model were reduced by keep-out zone design for the proposed design of the copper shielding electrode, and had 11 times reduction in out-of-plane direction especially, according to the nonlinear analysis as the stress concentration point in the shielding electrode moved. Moreover, the design with a thinner shielding electrode, thinner glass substrate and higher CTE of the glass substrate also lowered the maximum von Mises stress. On the other hand, the stress level during the operating temperature, without considering residual stress, overestimated up to five times in the proposed design.

Originality/value
In this study, valuable suggestions are proposed for the design of chips with pressure sensors embedded in accelerometers.
Study on self-cleaning performance and hydrophobicity of TiO2/silane coatings
Authors: Syafiq A. , Pandey A.K. , Balakrishnan Vengadaesvaran , Rahim Nasrudin Abd 
Published: January 2019

Purpose
The paper aims to investigate the effect of Degussa P-25 Titanium Dioxide (TiO2) nanoparticles on hydrophobicity and self-cleaning ability as a single organic coating on glass substrate.

Design/methodology/approach
Two methods have been used to enhance the hydrophobicity on glass substrates, namely, surface modification by using low surface energy isooctyltrimethoxysilane (ITMS) solution and construction of rough surface morphology using Degussa P-25 TiO2 nanoparticles with simple bottom-up approach. The prepared sol was applied onto glass substrate using dip-coating technique and stoved in the vacuum furnace 350°C.

Findings
The ITMS coating with nano TiO2 pigment has modified the glass substrate surface by achieving the water contact angle as high as 169° ± 2° and low sliding angle of 0° with simple and low-cost operation. The solid and air phase interface has created excellent anti-dirt and self-cleaning properties against dilute ketchup solution, mud and silicon powder.

Research limitations/implications
Findings will be useful in the development of self-cleaning and anti-dirt coating for photovoltaic panels.

Practical implications
Sol method provides the suitable medium for the combination of organic–inorganic network to achieve high superhydrophobicity and optimum self-cleaning ability.

Originality/value
Application of blended organic–inorganic sol as self-cleaning and anti-dirt coating film.
Preparation and flame retardancy of epoxy resin phosphoric acid modified poly-acrylate resin
Authors: Xu Buqin , Xu Guilong , Qiao Hui , Liang Yun , Yang Jin , Hu Jian 
Published: January 2019

Purpose
The flammability of poly-acrylate (PA) resin is a major disadvantage in applications that require flame resistance. It has been reported that a flame-retardant PA resin could be prepared by covalent incorporate phosphorous containing monomer with vinyl group via free radical polymerization, and the prepared modified PA resin is expected to exhibit better flame resistance than those by an additive approach. However, the phosphorus-containing monomers reported previously are made from expensive or toxic materials, and the production procedure is tedious and under harsh reaction conditions, which are not feasible for industrial application. Therefore, the purpose of this paper is the preparation of flame-retardant PA resin modified by epoxy resin phosphorous acid (EPPA) and the study of its flame retardancy.

Design/methodology/approach
EPPA is first prepared by epoxy resin E-51 and phosphorous acid and then used to prepare phosphorous containing PA resin by free radical polymerization. The flame retardancy of the prepared EPPA-modified PA (EPPA-PA) resin is studied.

Findings
The results show that EPPA can graft onto the PA polymer chain by free radical polymerization, the flame retardancy of the EPPA-PA resin increases as the EPPA content increasing. The flame retardancy of EPPA-PA resin prepared reaches 27.8% and can pass the V-0 rating in the UL-94 test when EPPA content is 30.0%. SEM and EDS results indicate that phosphorous element in the EPPA-PA resin shows a condensed-phase flame retardant effect.

Research limitations/implications
The grafting degree of EPPA cannot be accurately tested.

Practical implications
It is expected that the large-scale production of this epoxy resin phosphoric acid modified PA resin will enable practical industrial applications.

Originality/value
This method for synthesis of epoxy resin phosphoric acid modified PA resin is newfrangled.
Study on inert solvent for preparation based on GO/EP composite
Authors: Hu Guangkai , Zhang Xiaorui , Liu Lizhu , Ling Weng , Cui Weiwei 
Published: January 2019

PurposeThe dispersity of graphene oxide (GO) has an important effect on the properties of epoxy resin (EP) composites. Many modification and dispersion methods require the use of inert solvents which do not participate in the modification reaction, although GO can be uniformly dispersed in water and alcohol solvents. Based on this requirement, several inert solvents were selected as dispersion solvents to find out the suitable inert solvent for GO dispersion into EP matrix.Design/methodology/approachSeveral inert solvents with different solubility parameters were selected as dispersion solvents to prepare GO/EP composite. The microstructure, mechanical properties, insulation properties, dielectric properties and thermal property of the composite were characterized, which was due to find suitable inert solvent for GO dispersion into EP matrix.FindingsThe dispersity of N, N-dimethylformamide (DMF) was the best stable suspension state when it was used as solvent instead of occurring sedimentation and agglomeration. Moreover, DMF was further confirmed as a suitable inert solvent for the dispersion of GO into EP according to the mechanical properties, insulation properties and thermal conductivity characterization.Research limitations/implicationsThe dispersion of GO in solvents has already been researched, but the traditional solvents, such as alcohols and water, has shown their limitations with the increase of modification methods, which were not suitable for the modification environment such as cyanate graft modification. Therefore, it was very important to choose a kind of inert solvent for dissolving EP matrix and dispersing GO better.Originality/valueSeveral inert solvents were used to disperse GO into EP, and the influence of different dispersing solvents on the adhesive was discussed through the analysis of the mechanical properties, insulation properties and thermal conductivity, which was due to explore the inert solvent suitable for GO dispersion.
Dietitians' perspectives on patient barriers and enablers to weight management: An application of the social‐ecological model
Authors: Aboueid Stephanie , Pouliot Catherine , Nur Teeyaa , Bourgeault Ivy , Giroux Isabelle 
Published: January 2019

AimDietitians are nutrition experts who conduct nutrition assessments and provide support to patients seeking to manage their weight. The aim of the present study was to assess dietitians' perspectives on the barriers and enablers encountered by patients during their weight management journey.MethodsFourteen individual semi‐structured interviews were conducted over a 3‐month period in 2017 with dietitians working in Ontario, Canada. All interviews were audio‐recorded and transcribed verbatim. Two researchers coded the data independently using a directed content analysis approach.ResultsEmerging themes were classified at societal, community, relationship, individual levels of the social‐ecological model (SEM). Barriers included low socioeconomic status, ‘go big or go home approach’, lack of knowledge and cooking skills, lack of time, emotional eating, unsupportive home and work environments, discrimination and weight bias, lack of communication between health professionals, and low accessibility to healthy foods. Enablers included community programs, workplaces promoting healthy behaviours, and ongoing clinical support. Dietitians mentioned that patients encounter many barriers that may coexist and hinder weight management and/or maintenance of lost weight.ConclusionsCommunication between health team members and ongoing patient support in the clinical setting are required. A whole‐of‐government, whole‐of‐society approach is needed to target the various aforementioned barriers at various level of the SEM.
Buyer power and mutual dependency in a model of negotiations
Authors: Inderst Roman , Montez Joao 
Published: January 2019

AbstractWe study bilateral bargaining between several buyers and sellers in a framework that allows both sides, in case of a bilateral disagreement, flexibility to adjust trade with each of their other trading partners and receive the gross benefit generated by each adjustment. A larger buyer pays a higher per‐unit price when buyers' bargaining power in bilateral negotiations is sufficiently low, and a lower price otherwise. An analogous result holds for sellers. These predictions, and the implications of different technologies, are explained by the fact that size is a source of mutual dependency and not an unequivocal source of power.