bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Kualitas Jaringan Internet Menggunakan Parameter Quality Of Service di Kecamatan Bangkalan
Authors: Alhimni Ahmad Marzuq 
Published: December 2024

Abstrak - Quality of Service atau QoS adalah metode penilaian berkaitan dengan seberapa baik suatu jaringan komputer dan merupakan usaha dalam menentukan karakteristik beserta sifat dari suatu layanan. QoS dipergunakan dalam menilai kumpulan artribut kinerja yang sudah dispesifikasikan serta diasosiasikan pada suatu layanan. Mengacu pada kapabilitas jaringan dalam memfasilitasi layanan lebih baik dalam traffic jaringan komputer tertentu dengan teknologi yang berbeda. Tentunya QoS ini sudah mempunyai penilaian yang berstandarisasi TIPHON (Telecommunications and Internet Protocol Harmonization Over Network). Penelitian ini bertujuan untuk menilai kualitas jaringan dengan melakukan pengukuran kualitas rata-rata jaringan yang ada di Kecamatan Bangkalan. Pada penelitian ini menggunakan tiga parameter yaitu Throughput, Delay, dan Packet Loss. Hasilnya menunjukkan rata-rata nilai pada setiap parameter seperti (1)Throughput, (2)Delay, dan (3)Packet Loss di Kelurahan Mlajah sebesar (1)62,83 kbps (2)15,5 ms (3)0%, Kelurahan Kemayoran (1)275,28 kbps (2) 4,75 ms (3)0%, Kelurahan Demangan (1)364,085 kbps (2) 2,9 ms (3)0%, Kelurahan Pangeranan (1) 127,355 kbps (2) 8,8 ms (3)0%, dan Kelurahan Kraton (1) 165,68 kbps (2) 6,1 ms (3)0%. Hasil penelitian ini dapat disimpulkan bahwa semua kelurahan yang menjadi sampel mendapatkan nilai 3 dan masuk kategori Memuaskan menurut penilaian dengan standar QoS.Kata kunci : Quality of Service, Throughput, Delay, Packet Loss. Abstract - Quality of Service or QoS is an assessment method related to how good a computer network is and is an effort to determine the characteristics and nature of a service. QoS is used to assess a collection of performance attributes that have been specified and associated with a service. Refers to network capabilities in facilitating better services in certain computer network traffic with different technologies. Of course, this QoS already has a standard assessment of TIPHON (Telecommunications and Internet Protocol Harmonization Over Network). This research aims to assess network quality by measuring the average quality of the network in Bangkalan District. This research uses three parameters, namely Throughput, Delay, and Packet Loss. The results show that the average value for each parameter such as (1) Throughput, (2) Delay, and (3) Packet Loss in Mlajah Village is (1) 62.83 kbps (2) 15.5 ms (3) 0%, Kemayoran Village (1)275.28 kbps (2) 4.75 ms (3)0%, Demangan Village (1)364.085 kbps (2) 2.9 ms (3)0%, Pangeranan Village (1) 127.355 kbps ( 2) 8.8 ms (3)0%, and Kraton Village (1) 165.68 kbps (2) 6.1 ms (3)0%. The results of this research can be concluded that all sub-districts in the sample received a score of 3 and were in the Satisfactory category according to the assessment using QoS standards.Keywords: Quality of Service, Throughput, Delay, Packet Loss.
Pemanfaatan Fitur Instagram untuk Efektivitas Komunikasi
Authors: Uddin Badie , Maharani Aprilia Zahra , Baren Kailal Wafa Auladal 
Published: December 2024

Abstrak - Penelitian ini bertujuan untuk menganalisis pemanfaatan fitur Instagram dalam meningkatkan efektivitas komunikasi antara individu dan organisasi. Instagram menjadi platform media sosial paling populer yang menawarkan berbagai fitur seperti Stories, IGTV, Reels, dan Direct Messages. Fitur ini dapat digunakan untuk berkomunikasi dengan audiens secara efektif dan interaktif. Metode penelitian yang digunakan adalah survei dan analisis konten dengan melibatkan sejumlah pengguna aktif Instagram sebagai responden. Hasil penelitian menunjukkan bahwa fitur Instagram dapat meningkatkan efektivitas komunikasi melalui peningkatan keterlibatan, penyampaian pesan lebih visual dan kreatif, serta kemudahan dalam berbagi informasi secara langsung, Selain itu, penggunaan fitur Stories terbukti lebih efektif dalam membangun hubungan personal dan interaksi langsung dengan audiens. Penelitian ini menyimpulkan bahwa pemanfaatan fitur Instagram secara strategis dapat menjadi alat komunikasi yang efektif, baik untuk keperluan individu maupun organisasiKata kunci: Instagram, Komunikasi, Media Sosial, Efektivitas, Fitur Abstract - This research aims to analyze the use of Instagram features in increasing the effectiveness of communication between individuals and groups. Instagram, as one of the most popular social media platforms, offers various features such as Stories, IGTV, Reels, and Direct Messages which can be used to communicate with the audience more effectively and interactively. The research method used was a survey and content analysis, involving a number of active Instagram users as respondents. The research results show that Instagram features can increase communication effectiveness through increasing engagement, delivering more visual and creative messages, and making it easier to share information in real-time. Apart from that, using the Stories and Direct Messages features has proven to be more effective in building personal relationships and direct interaction with the audience. This research concludes that strategic use of Instagram features can be a very effective communication tool, both for personal and organization purposes.Keywords: Instagram, Communication, Social Media, Effectiveness, Feature
Effects of nitric acid concentration, hydrolisis time and particle size on moisture content and acid degree of dexrin from janeng starch
Authors: Sari Putri Meutia 
Published: December 2024

Janeng (Dioscorea hispida Dennest) is an excellent source for starch raw materials in the manufacture of dextrin, a product resulting from starch degradation through hydrolysis with acids or enzymes. The various methods of dextrin production, the dry hydrolysis method of starch using an acid catalyst is the most popular, and in this study, citric acid (HNO3) was selected. The purpose of this study was to determine the effect of HNO3 concentration (0.5N, 1N, 1.5N), hydrolysis time time (20, 30, 40 min) and particle size (60, 80, 100 mesh) on the moisture content and acid degree of dextrin and to see the optimum conditions of the those variables. This research used response surface method (RSM) based on central composite design (CCD). The result showed that HNO3 concentration, hydrolysis time and particle size had a significant effect on water content and acid degree. The higher the HNO3 concentration, the longer the hydrolysis time and the larger the particle size, the lower the water content. The higher the HNO3 concentration, the longer the hydrolysis time and the finer the particle size, the higher the acid degree. The optimum condition was obtained at a HNO3 concentration of 0.5 N with a hydrolysis time of 20 minutes and a particle size of 60 mesh with optimum predicted dextrin content of 7.12%, moisture content of 6.53% and acid degree of 0.92%.
PORTRAIT OF CLEAN AND HEALTHY LIVING BEHAVIOR (PHBS) OF BOARDING SCHOOL STUDENTS IN CILEGON CITY
Authors: Pertiwi Wiwik Eko , Octofiyani Yanti 
Published: December 2024

Clean and Healthy Living Behavior (PHBS) is a manifestation of healthy living orientation in individual, family and community cultures with the aim of improving, maintaining and protecting their health, both physically, mentally, and spiritually and socially. This study aims to determine the description of Clean and Healthy Living Behavior (PHBS) in Madrasah Aliyah (MA) Boarding School students in Cilegon City in 2022. This study is a descriptive study with a research population of all Madrasah Aliyah class X and XI students as many as 208 students. The sample of this study was 160 respondents taken by simple random sampling. Method using proportional sampling technique. Research shows that 51.3% of students' PHBS includes poor hands, hand washing behavior with soap and flowing water in the poor category (29.1%), healthy snack consumption behavior in the poor category (37.5%), the use of clean and healthy latrines in the poor category (44.4%), garbage disposal behavior is included in the poor category (71.9%), as many as 20.6% of students smoke at school, as many as 61.3% of students do not spit anywhere. As many as 71.9% of students litter, mosquito larvae eradication behavior is not good (58.1%). Based on the results of the study, it can be concluded that more than 50% of PHBS MA Boarding School students in Cilegon City are categorized as poor.
Risk and protective factors for coronavirus disease 2019 (COVID-19) in allergic rhinitis patients: a national survey in China
Authors: Yang Xiaozhe , Sima Yutong , Zhao Jinming , Zhang Jing , Wang Xiangdong , Zhang Luo 
Published: December 2024

BackgroundSeveral epidemiological studies have shown that allergic rhinitis (AR) patients are more susceptible to coronavirus disease 2019 (COVID-19).ObjectiveWe aim to investigate the risk factors for COVID-19 in AR patients.MethodsA retrospective nationwide cohort study was conducted based on a questionnaire survey in China. The baseline characteristics, region of residence, smoking and drinking status, comorbidities, vaccination status and previous infection information were obtained. Allergen test results, the SARS-CoV-2 nucleic acid test, and antigen detection results were collected. Information on AR and comorbid medication use pre-SARS-CoV-2 infection was also collected. Binary logistic regression and analysis of covariance (different adjusted models) were conducted.ResultsIn all, 830 AR patients were included; 627 patients (75.54%) were infected with SARS-CoV-2. AR comorbid with allergic conjunctivitis (AC) was a protective factor [OR: 0.525 (95% CI = 0.296–0.929), P = 0.027] against SARS-CoV-2 infection, while AR comorbid with food allergy was a risk factor [OR: 6.404 (95% CI = 1.349–30.402), P = 0.0195]. Although fewer patients received four doses of the vaccine, the results showed a significant protective effect against SARS-CoV-2 infection in AR patients [OR: 0.093 (95% CI = 0.025–0.348), P = 0.0004]. Underweight was a protective factor against COVID-19 [OR: 0.287 (95% CI = 0.147–0.562), P = 0.0003] after full multivariable adjustment. Overweight was associated with a 2.071-fold higher risk for COVID-19 compared with normal weight [(95% CI = 1.045–4.105), P = 0.0370]. Additionally, house dust mite (HDM)-specific allergies were also protective against COVID-19 [OR: 0.537 (95% CI = 0.290–0.996), P = 0.0484].ConclusionsThis study revealed underlying protective and risk factors, which might be used to improve the management of AR and COVID-19.
Functional role of the biofilm regulator CsgD in Salmonella enterica sv. Typhi
Authors: González Juan F. , Laipply Baileigh , Sadowski Victoria A. , Price Matthew , Gunn John S. 
Published: December 2024

IntroductionTyphoid fever is an infectious disease primarily caused by Salmonella enterica sv. Typhi (S. Typhi), a bacterium that causes as many as 20 million infections and 600,000 deaths annually. Asymptomatic chronic carriers of S. Typhi play a major role in the transmission of typhoid fever, as they intermittently shed the bacteria and can unknowingly infect humans in close proximity. An estimated 90% of chronic carriers have gallstones; biofilm formation on gallstones is a primary factor in the establishment and maintenance of gallbladder carriage. CsgD is a central biofilm regulator in Salmonella, but the S. Typhi csgD gene has a mutation that introduces an early stop codon, resulting in a protein truncated by 8 amino acids at the C-terminus. In this study, we investigate the role of role of CsgD in S. Typhi. MethodsWe introduced a fully functional copy of the csgD gene from S. Typhimurium into S. Typhi under both a native and a constitutive promoter and tested for red, dry, and rough (Rdar) colony morphology, curli fimbriae, cellulose, and biofilm formation. Results and discussionWe demonstrate that although CsgD-regulated curli and cellulose production were partially restored, the introduction of the S. Typhimurium csgD did not induce the Rdar colony morphology. Interestingly, we show that CsgD does not have a significant role in S. Typhi biofilm formation, as biofilm-forming capacities depend more on the isolate than the CsgD regulator. This data suggests the presence of an alternative biofilm regulatory process in this human-restricted pathogen.
Effectiveness of written emotional disclosure interventions for eating disorders: a systematic review and meta-analysis
Authors: Wang Yufei , Xu Tao , Tao Yuexian , Cai Xintong 
Published: December 2024

BackgroundEating disorders are illnesses that can seriously impair the health and wellbeing of patients. Written emotional disclosure has been recognized as a therapeutic technique that may be helpful in aiding patients’ emotional and psychological adjustment. However, it is unclear what favorable effects eating disorder patients can derive from written emotional disclosure therapy. This study aimed to review the effectiveness of written emotional disclosure in treating eating disorders using a systematic review and meta-analysis.ObjectiveThis study was to examine the validity of written emotional disclosure intervention for eating disorders as well as to provide guidelines for the management of eating disorders in patients.MethodsResearchers independently developed inclusion and exclusion criteria according to the PICOS principle and systematically searched English literature databases such as PubMed, Medline, Web of Science, Cochrane Library, CINAHL, EBSCO, Embase, and so on, from the time of library construction to December 2023. Cochrane Risk of Bias version 2 (RoB 2) was used to evaluate studies included in this review. All the studies included in this study were randomized controlled trials. Accurate information was extracted and then subjected to meta-analysis with Review Manager 5.4 software. The credibility of the evidence of the studies was assessed using GRADEprofiler 3.6 software.ResultsThe final analysis included 13 randomized controlled trials involving 1,444 participants. The written emotional disclosure intervention can decrease eating disorder symptoms scores (SMD = −0.20, 95% CI [−0.34, −0.05], Z = 2.59, p = 0.01), body dissatisfaction scores (SMD = 0.37, 95% CI [0.21, 0.52], Z = 4.59, p &lt; 0.001), and thin ideal internalization score (SMD = 0.42, 95% CI [0.22, 0.62], Z = 4.12, p &lt; 0.001). Anxiety scores (MD = 0.43, 95% CI [−0.77, 1.63], Z = 0.70, p = 0.48), depression scores (MD = −0.66, 95% CI [−1.78, 0.47], Z = 1.14, p = 0.25) and negative affect scores (SMD = 0.51, 95% CI [−0.24, 1.27], Z = 1.33, p = 0.18), with no statistically significant differences.ConclusionIn conclusion, this systematic review analyzed the existing literature and showed that written emotional disclosure intervention is effective in alleviating eating disorder symptoms and patients’ body image problems, but there is insufficient evidence in alleviating depression, anxiety, and negative affect. However, the evidence is limited. Therefore, more research is needed in the future to further enrich the evidence for written emotional disclosure intervention in the field of eating disorders.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/,CRD42023445577.
PENTINGNYA SOFT SKILLS TERHADAP PENGEMBANGAN KARIR GEN Z BAGI SISWA/I SMK KARYA NASIONAL, KAB. KUNINGAN JAWA BARAT
Authors: Umi Hanik Makmuroh  , Venny Oktaviany  , Eka Ahadiyat Suryana  , Nunung Kurniasih  , Wati Rahayu  
Published: December 2024

The aim of this Community Service (PKM) is to provide knowledge and skills regarding Soft Skills to students SMK Karya Nasional, Kab. Kuningan Jawa Barat. Especially in improving their skills through guidance in improving Soft Skills abilities. The prospect of improving Soft Skills aims to train personality, communication skills or personal attributes that are needed to be able to provide good performance in a job or business. The Soft Skills they process will make it easier for students to interact with the environment they enter. The activities of this community service program are to provide outreach to students at SMK Karya Nasional as Generation Z, providing guidance or counseling which can improve Soft Skills through many supportive activities. This was done as an effort to improve Soft Skills for generation z in order to face the era of industrial revolution 4.0
A New Insight into the Mechanism of Atrazine-Induced Neurotoxicity: Triggering Neural Stem Cell Senescence by Activating the Integrated Stress Response Pathway
Authors: Chen Jian , Dai Xue-Yan , Malhi Kanwar K. , Xu Xiang-Wen , Tang Yi-Xi , Li Xiao-Wei , Li Jin-Long 
Published: December 2024

Atrazine (AT), a widely utilized chemical herbicide, causes widespread contamination of agricultural water bodies. Recently, exposure to AT has been linked to the development of age-related neurodegenerative diseases (NDs), suggesting its neurotoxicity potential. As an endocrine disruptor, AT targets the hypothalamus, a crucial part of the neuroendocrine system. However, the toxicological mechanism of AT exposure to the hypothalamus and its correlation with ND development remain unexplored. Our results indicated that AT exposure caused significant morphological and structural damage to the hypothalamus, leading to the loss of mature and intact neurons and microglial activation. Furthermore, hypothalamic neural stem cells (HtNSCs) were recruited to areas of neuronal damage caused by AT. Through in vivo and in vitro experiments, we clarified the outcomes of AT-induced HtNSC recruitment alongside the loss of mature/intact neurons. Mechanistically, AT induces senescence in these recruited HtNSCs by activating integrated stress response signaling. This consequently hinders the repair of damaged neurons by inhibiting HtNSC proliferation and differentiation. Overall, our findings underscore the pivotal role of the integrated stress response pathway in AT-induced HtNSC senescence and hypothalamic damage. Additionally, the present study offers novel perspectives to understand the mechanisms of AT-induced neurotoxicity and provides preliminary evidence linking AT contamination to the development of NDs.
Vascular Smooth Muscle Cells Transdifferentiate into Chondrocyte-Like Cells and Facilitate Meniscal Fibrocartilage Regeneration
Authors: Yan Wenqiang , Cheng Jin , Wu Haoda , Gao Zeyuan , Li Zong , Cao Chenxi , Meng Qingyang , Wu Yue , Ren Shuang , Zhao Fengyuan , Wang Hongde , Liu Ping , Wang Jianquan , Hu Xiaoqing , Ao Yingfang 
Published: December 2024

The effective and translational strategy to regenerate knee meniscal fibrocartilage remained challenging. Herein, we first identified vascular smooth muscle cells (VSMCs) transdifferentiated into fibrochondrocytes and participated in spontaneous meniscal regeneration using smooth muscle cell lineage tracing transgenic mice meniscal defect model. Then, we identified low-intensity pulsed ultrasound (LIPUS) acoustic stimulus enhanced fibrochondrogenic transdifferentiation of VSMCs in vitro and in vivo. Mechanistically, LIPUS stimulus could up-regulate mechanosensitive ion channel Piezo1 expression and then activate the transforming growth factor β1 (TGFβ1) signal, following repression of the Notch signal, consequently enhancing fibrochondrogenic transdifferentiation of VSMCs. Finally, we demonstrated that the regular LIPUS stimulus enhanced anisotropic native-like meniscal fibrocartilage tissue regeneration in a beagle canine subtotal meniscectomy model at 6 months postoperatively. The single-cell RNA sequencing analysis confirmed the role of VSMC fibrochondrogenic transdifferentiation in meniscal regeneration.
КОНСТРУКТИВНІ ОСОБЛИВОСТІ ДОСЛІДНОЇ УСТАНОВКИ ТА ЧИСЛОВІ ДОСЛІДЖЕННЯ ПРОЦЕСУ ТЕРМОХІМІЧНОЇ ПЕРЕРОБКИ БІОМАСИ. ЧАСТИНА 3 ВПЛИВ ТЕПЛОЄМНОСТІ Й ТЕПЛОВОГО ЕФЕКТУ ТЕРМОРОЗПАДУ НА ШВИДКІСТЬ ПРОГРІВАННЯ ШАРУ ЧАСТИНОК WOOD BIRCH
Authors: Рохман Б. Б. , Кобзар С. Г. 
Published: December 2024

Третя частина цієї роботи присвячена теоретич­ному дослідженню впливу теплоємності біомаси, граничних умов, рециркуляції піролізних газів, зовнішніх і внутрішніх теплових потоків на час прогріву нерухомого шару піролізера, що складається з частинок Wood Birch еквівалентного діаметра 10 мм. Розглядалися три варіанти прогріву шару за рахунок: а) електрообігріву зовнішньої та внутрішньої поверхонь піролізера; б) електрообігріву зовнішньої поверхні та обігріву внутрішньої поверхні піролізера продуктами згоряння; в) двох електро­обігрівачів та рециркуляційного піролізного газу з температурою 800 °С. Показано, що: 1) урахування теплового ефекту процесу терморозпаду в рівнянні теплової енергії частинок приводить до зменшення часу прогріву шару біомаси в 1,33 раза та підвищення швидкості прогріву шару до 987 °С/хв; 2) рециркуляція високотемпературних піролізних газів, що надходять до піролізера, який обмежений зовнішнім, D = 220 мм, і внутрішнім, d = 150 мм, діаметрами, зменшує час прогріву шару в 1,39 раза, внаслідок чого швидкість прогріву частинок шару зростає від 987 до 1373 °С/хв; 3) рециркуляція піролізних газів сприяє організації швидкого піролізу в разі підвищення зовнішньо го діаметра піролізера від 220 до 240 мм та від 220 до 300 мм, внаслідок чого відбувається зменшення швидкостей прогріву шару від 1373 до 1295,3 °С/хв та від 1373 до 1223 °С/хв відповідно; 4) результати розрахунку складу змішаного піролізного газу за tg = 800 °С: CO2 = 7,14 %, CO = 51,4 %, H2 = 15,56 %, C1,16H4 = 23,72 % (CH4 = 16,6 % та C2H4 = 7,116 %), N2 = 0,296 % добре збігаються з результатами експерименту піролізу Wood Birch за tg = 800 °С: CO2 = 8,3 %, CO = 50,70 %, H2 = 16,8 %, CH4 = 16,2 % і C2H4 = 7,9 %.
Synthesis, Antibacterial Evaluation and Study Molecular Docking of New derivatives from sulfapyridine
Authors: Maryam Methaq Najm  , Hanan Faleh Mohsein  
Published: December 2024

Sulfa pyridine is a sulfa-derived antibiotic. It works to inhibit the activity and reproduction of bacterial cells, by inhibiting the production of some enzymes that bacteria need for their growth and activity. Therefore, in this research, we decided to increase the effectiveness of the Sulfa pyridine compound by adding some groups such as azomethine, as well as preparing some derivatives of thiazolidinone and derivatives , thiazine, hydroquinazolone, and oxazepine, Then evaluating the effectiveness of some prepared derivatives against two types of gram-negative and gram-positive bacteria, such as E. coli and Staphylococcus aureus and molecular docking study against skin cancer .
New azo-azomethine ligand derived from Imidazole with divalent metal complexes , synthesis ,spectroscopic and biological activity studies
Authors: Zahraa Rasheed Hassani  , Mithaq Saeed Mohammed  
Published: December 2024

The study involves the preparation of a heterocyclic aromatic Azo-Azomethine compound in a base medium . The compound was identified by partial elemental analysis, mass spectrometry, infrared spectroscopy, ultraviolet-visible spectroscopy, NMR spectroscopy and many other properties. Physical properties. He also prepared a series of octahedral coordination complexes for the ions of manganese(II), iron(II), cobalt(II), nickel(II), copper(II), zinc(II), cadmium(II) and mercury(II) a tetrahedral complex for the single positively charged silver ion and a flat square complex for the triple gold ion. The prepared new compounds proved their vital activity as antioxidant , anti-cancer compounds, and compounds with high color stability.