bluuebunny/crossref_metadata_2025_split huggingface dataset:
The titanium triumph: Exploring the transformative world of dental implants
Authors: Rohith Akula Sai , Gupta Prachi , Fernandes Alcina , Khan Furkhan Ahmed , Ashok Anvika , Vijaya Sheetal 
Published: November 2024

Dental implants have revolutionized tooth replacement by offering a permanent and lifelike solution. Titanium, due to its exceptional biocompatibility and mechanical properties, has emerged as the material of choice for dental implants. Dr. Per-Ingvar Brånemark's discovery of osseointegration in the 1960s paved the way for the widespread adoption of titanium implants, marking a paradigm shift in dental prosthetics.The aim of this article is to explore the transformative role of titanium in dental implantology, focusing on its properties, evolution, types, advancements, clinical considerations, challenges, and future directions.This review synthesizes literature on the properties of titanium, the evolution of dental implants, types of titanium implants (endosseous, subperiosteal, transosseous), advancements in implant design and technology, clinical considerations, patient outcomes, challenges, and future directions.Titanium exhibits outstanding biocompatibility, mechanical strength, and corrosion resistance, making it ideal for dental implants. Endosseous implants, the most common type, mimic natural tooth roots and undergo osseointegration for stability. Subperiosteal implants rest on the jawbone surface, while transosseous implants penetrate through the bone. Advancements in implant design and technology have improved outcomes, but challenges such as peri-implantitis persist.Titanium implants have transformed dental care, offering patients reliable and durable solutions for tooth loss. Despite challenges, ongoing research and technological innovations hold promise for further enhancing implant therapy. The future of dental implants is bright, with continued advancements poised to improve patient outcomes and quality of life.
Knowledge and attitude of general dental practitioners and pedodontists toward silver diamine fluoride in Maharashtra
Authors: Sachdev Sanpreet Singh , Padawe Dimple , Wankhade Ajinkya , Takate Vilas , Dighe Kishor , Agrawal Arushi 
Published: November 2024

Despite advancements in preventive dentistry, the prevalence of caries, particularly in pediatric populations, continues to be a significant public health challenge. Silver diamine fluoride (SDF) has emerged as a promising and cost-effective intervention in preventing and managing dental caries, demonstrating notable success in arresting the progression of cavities. The present study aims to investigate the knowledge and attitudes of general dental practitioners (GDP) and pedodontists in Maharashtra concerning silver diamine fluoride The present cross-sectional study was conducted using a 10-point questionnaire comprising questions relevant to the knowledge and attitude of general practitioners and pediatric dentists regarding the use of SDF. The survey was circulated to 578 dental professionals of which 332 opted to fill out the form, making the survey response rate of 57.44%. The datasheet of responses was extracted through Google Sheets and subjected to statistical analysis: The study population (n=295) comprised 249 GDP and 46 Pediatric dentists. Despite 75.6% of respondents being aware of SDF, only 43.7% were aware of the Silver-modified atraumatic restorative technique. The awareness about both, the advantages as well as disadvantages of SDF was significantly lower (p&#60;0.05) among GDP. About 42% of respondents (n=124) were not aware of the fact that SDF application does not require local anesthetic or drilling. Findings from the present study highlight significant differences in knowledge levels between GDPs and pediatric dentists, emphasizing the need for targeted educational interventions tailored to the distinct needs of each group. Addressing these knowledge gaps is essential for promoting informed decision-making and optimizing the integration of SDF into routine dental practice.
The Impact of Combined Cranberry Supplementation and Weight Loss Diet on Inflammatory, Antioxidant, and Apoptosis Biomarkers in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized, Double-Blinded, Controlled Clinical Trial
Authors: Hormoznejad Razie , Shahi Majid Mohammad , Mahboobi Sepideh , Rahim Fakher , Helli Bijan , Alavinejad Pezhman , Dehghanseresht Narges , Sharhani Asaad 
Published: November 2024

Background: Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disease. The aim of this study is to evaluate the effect of combined weight loss diet and cranberry supplementation on anthropometric measurements, inflammation and antioxidant biomarkers in patients with NAFLD. Methods: In this randomized, double-blinded, and controlled clinical trial, 41 NAFLD patients were supplemented with either cranberry or placebo tablets for 12 weeks. Both groups followed a diet of 500-1000 calories less than the estimated energy requirements. Serum levels of total antioxidant capacity (TAC), malondialdehyde (MDA), cytokeratin 18 M30 (CK-18 M30), chemokine C-C motif ligand 2 (CCL2) and tumor necrosis factor alpha (TNF-α) were measured at both baseline and the end of the study. Results: Significant improvements in TAC were observed in the cranberry group and between the two groups (P=0.006 and P=0.011, respectively), but the changes in the placebo group were not significant (P=0.325). There were no statistically significant differences in the serum levels of MDA, CK-18 M30, CCL2 and TNF-α between the cranberry and the placebo groups (P>0.05). Conclusions: It seems that daily consumption of cranberry supplement would be beneficial in increasing serum levels of TAC. Further studies are needed to investigate the effects of anti-inflammatory and antioxidant properties of cranberry on NAFLD.
PENGEMBANGAN E-LKPD BERBASIS HOTS PADA MATERI PERSAMAAN DAN PERTIDAKSAMAAN LINEAR SATU VARIABEL
Authors: Apriliana Desi , Karim Karim , Suryaningsih Yuni 
Published: November 2024

Peserta didik kesulitan dalam menyelesaikan masalah yang berbentuk soal cerita. Khususnya mengaitkan gagasan matematika dengan kehidupan sehari-hari. Akibatnya, peserta didik merasa kesulitan, sehingga diperlukannya LKPD berbasis HOTS untuk mengatasi hal tersebut. LKPD juga dibuat dalam bentuk digital dikarenakan teknologi sekarang ini sudah berkembang sehingga mudah untuk mengaksesnya menggunakan smartphone atau komputer. Tujuan penelitian ini adalah untuk menganalisis proses dan menghasilkan LKPD elektronik berbasis HOTS menggunakan Liveworksheets pada materi persamaan dan pertidaksamaan linear satu variabel yang valid, praktis, dan efektif. R&D merupakan metode yang digunakan pada penelitian ini dengan model 4D, dibatasi hanya sampai tiga tahap yaitu, pendefinisian, perancangan, dan pengembangan. Tahap ketiga pengembangan dilakukan uji validitas sehingga diperoleh skor rata-rata (Va) sebesar 3,51 yang dikategorikan valid. Kemudian diperoleh nilai pratikalitasnya sebesar 79,18% yang memenuhi kriteria praktis dilihat dari angket respon peserta didik. LKPD juga efektif dilihat dari hasil jawaban LKPD yang telah dikerjakan peserta didik.
MENINGKATKAN HASIL BELAJAR SISWA KELAS V SDN SUNGAI LANGSAT MELALUI MODEL PEMBELAJARAN PBL DENGAN KONTEKS KERAJINAN ANYAMAN BAMBU
Authors: Fahjri Annisa Desti , Fajriah Noor , Sari Asdini 
Published: November 2024

Salah satu penyebab hasil belajar siswa yang tidak memuaskan disebabkan karena mereka kurang terlibat aktif dalam proses pembelajaran. Siswa terbiasa hanya menerima dan kurang diberikan masalah yang berkaitan dengan kehidupan sehari-hari. Khusus materi volume kubus dan balok, siswa kesulitan menyelesaikan masalah dalam kehidupan sehari-hari. Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar siswa setelah diterapkan Model Pembelajaran PBL (Problem Based Learning) kontek kerajinan anyaman bambu pada materi volume kubus dan balok. Penelitian ini merupakan Penelitian Tindak Kelas (PTK) yang dilakukan dalam dua siklus penelitian, masing-masing siklus terdapat empat tahapan penelitian yang terdiri dari tahap perencanaan, pelaksanaan, observasi, dan refleksi. Instrumen yang digunakan dalam pengumpulan data terdiri dari lembar observasi dan tes akhir. Analisis data dilakukan menggunakan metode analisis deskriptif kuantitatif yaitu pengolahan data yang diperoleh dari angka rata-rata (mean) dan persentase. Subjek yang terlibat dalam penelitian ini ialah siswa kelas V SDN Sungai Langsat. Hasil penelitian menunjukkan terjadi peningkatan hasil belajar sebanyak 50% dari siklus I ke siklus II secara klasikal setelah diterapkan model pembelajaran PBL. Berdasarkan hasil tersebut dapat disimpulkan bahwa model pembelajaran PBL dapat meningkatkan hasil belajar siswa kelas V SDN Sungai Langsat pada materi volume kubus dan balok.
Our Impact on Global Warming
Authors: Eidmann Annette , Geiger Felicitas , Heinz Tizian , Jakuscheit Axel , Docheva Denitsa , Horas Konstantin , Stratos Ioannis , Rudert Maximilian 
Published: November 2024

Background:
The health-care sector and particularly the surgical sector are major contributors to the exacerbation of the global climate crisis. Little is known about the carbon emissions caused by surgical procedures. Therefore, the aim of this study was to estimate the carbon footprint associated with common orthopaedic surgical procedures.

Methods:
Eight surgical procedures (total hip arthroplasty, total knee arthroplasty, knee arthroscopy, anterior cruciate ligament reconstruction, shoulder arthroscopy, elective foot surgery, revision hip arthroplasty, and revision knee arthroplasty) were selected for analysis. The inventory process was performed according to the Greenhouse Gas Protocol for all activity occurring in the operating room.

Results:
The carbon footprint (in CO2 equivalents, CO2e) ranged between 53.5 kg for knee arthroscopy and 125.9 kg for revision knee arthroplasty. Energy consumption accounted for 57.5% of all emissions, followed by other indirect emissions (38.8%) and direct emissions (3.7%). The largest single contributors were the supply chain (34.6%) and energy consumption for ventilation, heating, and air conditioning (32.7%).

Conclusions:
Orthopaedic surgical procedures produce considerable amounts of CO2. Reduction in and greening of energy consumption, as well as the decarbonization of the supply chain, would have the greatest impact in reducing the carbon footprint of orthopaedic surgical procedures.

Clinical Relevance:
Orthopaedic surgical procedures contribute to the climate crisis by emitting relevant amounts of CO2. It should therefore be imperative for all orthopaedic surgeons to endeavor to find solutions to mitigate the environmental impact of their practice.
Heart Shape to Fracture Distance: Characterizing Hydraulic Fracture Propagation before Hits
Authors: Li Peiyao , Jin Ge , Hammack Richard , Kohnke Colton , Wu Kan 
Published: November 2024

Summary
Estimating the distance from the hydraulic fracture tip to the monitor well can be useful for fracture characterization, well spacing optimization, and preventing parent-child well interference. A heart-shaped signal is referred to as the extensional precursor of a fracture hit recorded by crosswell strain measurements and can serve as a vital tool for such estimation. This study incorporates the 3D displacement discontinuity method (DDM) to understand the impact of fracture geometry and monitor well offset on the heart-shaped signal’s characteristics. Results from numerical simulation and analytical solutions reveal a strong linear correlation between the spatial extent of the heart-shaped signal and the fracture tip distance. This relationship was further developed to predict tip distance using field data from the Hydraulic Fracture Test Site 2 (HFTS2). A reasonable approximation result from field data further validates the methodology. In addition, it is worth noting that the estimation accuracy depends on the ratio between fracture dimension and tip distance. The findings of this study offer a novel approach for real-time monitoring and characterizing hydraulic fracture propagation, which can be further used for well spacing optimization in unconventional and enhanced geothermal system reservoir development, as well as caprock integrity monitoring for carbon sequestration projects.
An Aptamer and hydroxyapatite-silver-zinc oxide (HAP-Ag-ZnO) based novel electrochemical sensor for ultrasensitive H pylori detection
Authors: Rafique Saima , Akram Rizwan , Nasir Rubina , Naz Nafeesa , Shafique Adnan , Bashir Shazia , Haq Zeenat 
Published: November 2024

Abstract

A novel approach based on aptamer recognition was developed for the detection of Hsp 60. The aptasensor was developed using Hap-Ag-ZnO composites on GCE along with polythiophene (PP), as a conductive polymer to improve proficiency. The Hap-Ag-ZnO-PP composites have multiple functional group sites that facilitate aptamer immobilization on the GCE. This would increase the sensitivity, stability, and dynamic range of the developed aptasensor. EIS, CV, and SWV were employed to examine the performance of aptasensor. The decrease in electron transfer was observed as Hsp 60 protein interacted with the aptamer. A calibration curve was plotted between the peak current and the concentration of Hsp 60. The fabricated aptasensor showed an outstanding detection limit of 0.043 nM and a wide dynamic range of 0.05-300 nM. Moreover, the Hap-Ag-ZnO-polythiophene-based aptasensor exhibits exceptional reproducibility, repeatability, quick response time (20 min), good selectivity, and excellent stability (electrochemical and storage). Therefore, the prepared sensitive aptasensor provides a promising platform for clinical diagnostics and H pylori detection in real-world applications.
Synthetic CT generation from CBCT and MRI using the StarGAN in Pelvic Region
Authors: Wongtrakool Paritt , Puttanawarut Chanon , Changkaew Pimolpun , Piasanthia Supakiet , Earwong Pareena , Stansook Nauljun , Khachonkham Suphalak 
Published: November 2024

Abstract

Background
This study evaluates StarGAN, a deep learning model designed to generate synthetic CT (sCT) images from MRI and CBCT data via a single model. The goal is to provide accurate Hounsfield Unit (HU) data for dose calculation and compare StarGAN's performance to CycleGAN.
Methods
StarGAN and CycleGAN were trained on a pelvic cancer dataset consisting of 23 training, 5 validation, and 5 testing cases. The evaluation involved qualitative and quantitative analyses, with a focus on synthetic image quality and dose distribution calculations.
Results
For sCT generated from CBCT, the StarGAN demonstrated superior anatomical preservation in qualitative evaluations. Quantitatively, CycleGAN exhibited lower mean absolute error (MAE) values for body (42.77 ± 4.28 HU), soft tissue (36.97 ± 3.87 HU), and bone (138.17 ± 20.29), whereas StarGAN presented higher MAE values (50.81 ± 5.16 HU, 44.57 ± 5.14 HU, 153.36 ± 27.67 HU, respectively). Dosimetric evaluations revealed a mean dose difference (DD) within 2% for planning the target volume (PTV) and body, with a gamma passing rate (GPR) > 90% under 2%/2 mm criteria. For sCT generated from MRI, qualitative evaluation also favored StarGAN's anatomical preservation. The CycleGAN resulted in lower MAEs (79.77 ± 13.96 HU, 70.14 ± 16.26 HU, and 253.62 ± 30.85 HU), whereas the StarGAN resulted in higher MAEs (94.65 ± 7.41 HU, 80.75 ± 9.60 HU, and 353.58 ± 34.85 HU). Both models achieved a mean DD within 2% in the PTV and body, and GPR > 90%.
Conclusion
While CycleGAN exhibited superior quantitative metrics, StarGAN was better in terms of anatomical preservation, highlighting its potential for sCT generation in radiotherapy.
Explaining the position of aesthetics in Iran’s nursing leadership
Authors: poursaadat newsha , cheraghi mohammad ali , Esmaeili Maryam , hajibabaee fatemeh 
Published: November 2024

Abstract

Background and objective: Aesthetics can be explained and investigated in two contexts of beauty and sublimity. Aesthetics is often considered as a specific method of sensory perception or experience. Findings of qualitative studies should be used to objectify aesthetics in all areas of nursing, including management and leadership. This study was conducted in 2023 to explain the position of aesthetics in Iran’s nursing leadership in the teaching hospitals of Tehran University of Medical Sciences.
Method: This is a descriptive and qualitative study with conventional content analysis approach suggested by Granheim and Lundman. Research community included the leadership and management team of hospitals affiliated to Tehran University of Medical Sciences. Semi-structured and face-to-face individual interviews (28 in total) were conducted with the participants ( director nurses and supervisors and head nurses) to collect the data. purposeful and snowball methods were used for the sampling, which continued until data saturation.
Findings: A total of 1482 codes were extracted from 28 interviews, which were later summarized in three main categories (aesthetic thought, aesthetic speech and aesthetic action) and nine subcategories.
Conclusion: This study consolidates the findings of previous studies in terms of theoretical foundations of aesthetic leadership in the literature, and in regard to methodology, it facilitates the complementation of aesthetic nursing leadership model in the health care system. Therefore, it can help to objectify and explain the concepts of beauty and sublimity in the organizational life of nursing leaders in Iran's health care system.
Synergistic interaction between microbial nitrogen fixation and iron reduction in the environment
Authors: Li Ping , Liu Xiaohan , Bao Keman , Wang Yaqi , Wang Helin , Wang Yanhong , Jiang Zhou , Yang Yi , Yuan Songhu , Kappler Andreas , Wang Yanxin 
Published: November 2024

Abstract

Nitrogen (N) and iron (Fe) are essential but often limiting nutrients in ecosystems. Microbial nitrogen fixation (MNF) by diazotrophs and dissimilatory ferric iron (Fe(Ⅲ)) reduction (DIR) are environmentally friendly processes that sustain N and Fe availability. However, the interactions between these processes remain unclear. This study demonstrates a synergistic relationship between MNF and DIR in both laboratory and field settings. N fixation significantly increased heterotrophic Fe(Ⅲ)-reducing rates in diazotrophic DIR bacteria (DIRB) Klebsiella sp. N7 and Geobacter sulfurreducens PCA by 14.7- and 3.3-fold, respectively, while Fe(Ⅲ) reduction enhanced 15N fixation by up to 100%. Similar synergies were found between diazotroph Azospirillum humicireducens SgZ-5T and DIRB Shewanella oneidensis MR-1. Transcriptomic analysis revealed that N fixation upregulated genes associated with anaerobic respiration, accelerating Fe(Ⅲ) reduction through N supply. Simultaneously, Fe(Ⅲ) reduction provided the energy and electrons required for N fixation derived from the oxidation of organic carbon. These findings, validated across environmental samples from aquifers, hot springs, marine sediments, and soils, provide new insights into the coupled N, Fe, and C cycles in natural ecosystems.
A Public health wound: health and work among children engaged in worst forms of child labour in the informal sector in Dhaka, Bangladesh: a retrospective analysis of Médecins Sans Frontières Occupational health data from 2014 to 2023.
Authors: Caleo Grazia , Sadique Sohana , Yuce Didem , Dada Martins , Benvenuti Bianca , Joseph Jobin , Malden Debbie , Velivela Kalyan , Chowdhury Salim Mahmud , Mayienga Christabel , Shenjuti Tasmia , Sadacharamani Gayathrie , Masum Rezwanur Rahman , Sherlock Mark , Atim Hamza , Keating Patrick 
Published: November 2024

Abstract

Background: Bangladesh has the second highest burden of child labour in South Asia. The informal sector employs most of the children however, evidence and data on health including injuries and place of work for children are limited. As the deadline for the Sustainable Development Goals to end child labour by 2025 is approaching, it is paramount to document the impact of child labour on health. This study aims to contribute to this knowledge gap by presenting medical data from occupational health clinics set up by Médecins Sans Frontières (MSF) in an urban area of Dhaka, Bangladesh.
Methods: We did a retrospective analysis of health care records of children attending MSF occupational health clinics between February 2014 and December 2023 in Dhaka. We stratified the analysis by gender and age (<14 years and ≥14-<18 years). We looked at morbidities according to type of factory, whether children reported working with machinery, and examined nutritional and mental health (2018-2023) status.
Results: Over the study period, there were 10,200 occupational health consultations among children <18 years, of which 4945 were new/first time consultations. The average age of children attending their first consultation was 14.7 years, of which 61% were male. Fifteen percent reported living inside the factory. Musculoskeletal (26%) and dermatological (20%) were the most identified conditions, and 7.5% of consultations were for work-related injuries. Almost all children reported operating machinery. A higher proportion of male children had injuries (11% vs 2.5% in girls). Children working in metal factories accounted for most injuries (65%). Mood-related disorders accounted for 86% of the 51 mental health consultations. Half of all children were malnourished with higher levels in boys and those <14 years. Specific gender and age vulnerabilities were documented.
Conclusions
Findings suggest that children face hazardous realities, engaged in the worst form of labour, bearing important morbidity and injury burden. Weak enforcement of labour regulations in the informal sector ultimately enables child exploitation and suffering. Further research is essential to explore the intersectional dimensions of child labour, such as gender, age, and disability, to inform interventions aimed at eliminating child labour and its severe consequences in this and similar contexts.
Pressure-Induced Phase Transitions in Bilayer La3Ni2O7
Authors: Xie Weiwei , Xu Mingyu , Jose Greeshma , Rutherford Aya , Wang Haozhe , Zhang Stephen , Cava Robert , Zhou Haidong , Bi Wenli 
Published: November 2024

Abstract

La3Ni2O7 exists in two polymorphs: an unconventional structure with alternating layers of single- and triple-layered nickel-oxygen octahedra, and a classical double-layered Ruddlesden-Popper phase. In this study, we report the growth of single crystals of classical double-layered La3Ni2O7 using the floating zone method. Structural characterization under pressures up to 15.4 GPa reveals a gradual transition from orthorhombic to tetragonal symmetry near 12 GPa. Additionally, we present pressure and field-dependent electrical resistance measurements under pressures as high as 27.4 GPa, from which we construct a phase diagram.