bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unités monolexicales et unités polylexicales : entre équivalence sémantique et synonymie, le cas des adverbes
Authors: Oueslati Lassaâd 
Published: April 2018

Les unités polylexicales relèvent le plus souvent du figement dans la mesure où elles se caractérisent par une certaine globalité sémantique. Plus précisément, elles se caractérisent par leur non-compositionnalité. Cette caractéristique implique que les unités polylexicales se comportent exactement comme les unités monolexicales sur les plans syntaxique et sémantique. Tout comme les lexèmes simples, les séquences polylexicales établissent un réseau de relations sémantiques impliquant l’antonymie, la synonymie, l’hyperonymie, etc. Certains linguistes parlent d’équivalence sémantique en esquivant la synonymie. Par exemple, certains lexicologues donnent faire peur pour synonyme de effrayer ; avoir l’air pour synonyme de sembler ; en
dépit pour synonyme de malgré ; panier percé pour dépensier, etc. La synonymie existe donc entre les unités monolexicales et les unités polylexicales, toutes les parties du discours confondues. Les dictionnaires définissent les unités polylexicales en donnant et les antonymes et les synonymes. Par exemple, dans le Petit Robert électronique, on donne faussement, indûment, injustement pour synonymes de à tort ; et on donne aussi inconsidérément pour synonyme de à tort et à travers. Nous nous intéresserons, dans ce travail à la synonymie entre les adverbes simples et les séquences adverbiales figées. Nous mettrons l’accent sur le degré d’équivalence sémantique entre des unités du type en vain et vainement.

Cette investigation est de nature à nous permettre de vérifier le degré d’équivalence entre les unités polylexicales et les lexèmes simples. Nous pourrons aussi vérifier si les unités polylexicales servant de paraphrases aux adverbes en ment leur servent vraiment de synonymes. La notion d’emploi développée dans les travaux du LDI nous servira d’outil d’analyse pour mesurer le degré de synonymie entre les différentes unités lexicales adverbiales.
A taxonomic revision helps to clarify differences between the Atlantic invasive Ptilohyale littoralis and the Mediterranean endemic Parhyale plumicornis (Crustacea, Amphipoda)
Authors: Lo Brutto Sabrina , Iaciofano Davide 
Published: April 2018

Ptilohyaleexplorator (formerly Parhyaleexplorator), described by Arresti (1989), can be considered to be a synonym of west-Atlantic Ptilohyalelittoralis (Stimpson, 1853), based on morphological observations of paratypes and specimens recently collected in the type locality of Ptilohyaleexplorator. The first collections of Ptilohyalelittoralis, from the eastern Atlantic were from the port of Rotterdam (The Netherlands) in 2009 and later in Wimereux, Opal Coast (France) in 2014; however, the synonymy of Ptilohyaleexplorator with Ptilohyalelittoralis backdates to the first European record of Ptilohyalelittoralis in 1985 at La Vigne, Bay of Arcachon (France). This indicates that Ptilohyalelittoralis has been established along European Atlantic coast for many years.
An assessment of the nominal valid species belonging to the genus Ptilohyale was carried out and a comparison between the Atlantic Ptilohyalelittoralis and the very similar Mediterranean hyalid species, Parhyaleplumicornis, is presented based on morphological features and distribution. Due to the invasive ability of Ptilohyalelittoralis, a comparison between the two species is necessary.
La construction du commun comme politique post-capitaliste
Authors: Gibson-Graham J.K. , Cameron Jenny , Healy Stephen , De Roo Priscilla , Querrien Anne 
Published: April 2018

Aujourd’hui la planète est confrontée à l’absence de gestion de communs vitaux tels que l’air, le climat, l’eau. Il importe de construire des modalités collectives de gestion de ces communs, impliquant le maximum de parties prenantes. Pour cela, il faut sortir du capitalocentrisme, parallèle au phallocentrisme dénoncé par les féministes, pour lequel le commun serait engendré inévitablement par les contradictions du capitalisme. Il vaut mieux analyser la manière dont le commun se construit progressivement en mettant une ressource en commun quel que soit le régime de propriété. Trois exemples sont donnés : la qualité de l’air dans une ville australienne jouxtant une mine de charbon, où habitants et industriels ont reconnu peu à peu la nécessité de prévenir la pollution ; la menace sur la couche d’ozone qui a été conjurée à la fois par le Protocole de Montréal de 1985 et par une multitude d’actions en ce sens ; le développement des installations solaires domestiques par les citoyens australiens. À chaque fois une communauté d’acteurs s’est formée transversalement aux lignes de clivages de classe, et c’est une prolifération de ces communautés qui peut mettre l’énergie, l’atmosphère et d’autres ressources planétaires en commun. Il faudrait cependant que cette politique ait un nom, pour lequel l’article propose « La construction du commun ».
eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2
Authors: William Mirtha , Leroux Louis-Philippe , Chaparro Visnu , Lorent Julie , Graber Tyson E. , M’Boutchou Marie-Noël , Charpentier Tania , Fabié Aymeric , Dozois Charles M. , Stäger Simona , van Kempen Léon C. , Alain Tommy , Larsson Ola , Jaramillo Maritza 
Published: April 2018

Abstract
Macrophages represent one of the first lines of defense during infections and are essential for resolution of inflammation following pathogen clearance. Rapid activation or suppression of protein synthesis via changes in translational efficiency allows cells of the immune system, including macrophages, to quickly respond to external triggers or cues without de novo mRNA synthesis. The translational repressors eIF4E-binding proteins 4E-BP1 and 4E-BP2 (4E-BP1/2) are central regulators of proinflammatory cytokine synthesis during viral and parasitic infections. However, it remains to be established whether 4E-BP1/2 play a role in translational control of anti-inflammatory responses. By comparing translational efficiencies of immune-related transcripts in macrophages from wild-type and 4E-BP1/2 double-knockout mice, we found that translation of mRNAs encoding two major regulators of inflammation, IL-10 and PG-endoperoxide synthase 2/cyclooxygenase-2, is controlled by 4E-BP1/2. Genetic deletion of 4E-BP1/2 in macrophages increased endogenous IL-10 and PGE2 protein synthesis in response to TLR4 stimulation and reduced their bactericidal capacity. The molecular mechanism involves enhanced anti-inflammatory gene expression (sIl1ra, Nfil3, Arg1, Serpinb2) owing to upregulation of IL-10–STAT3 and PGE2–C/EBPβ signaling. These data provide evidence that 4E-BP1/2 limit anti-inflammatory responses in macrophages and suggest that dysregulated activity of 4E-BP1/2 might be involved in reprogramming of the translational and downstream transcriptional landscape of macrophages during pathological conditions, such as infections and cancer.
El asentamiento de la ficción seriada española en el extranjero (2005-2017). El caso de la adaptación norteamericana de Los misterios de Laura desde el punto de vista de sus creadores
Authors: Diego Patricia , Grandío Pérez María del Mar 
Published: April 2018

Este artículo tiene como objetivo principal reflexionar sobre las claves del éxito de las adaptaciones de producciones televisivas españolas en el extranjero. Para ello, se ofrece una recopilación de las series españolas que han sido adaptadas en otros mercados en la época de consolidación de este fenómeno (2005-2017), y se aborda un análisis de los valores de producción de la serie española de RTVE Los Misterios de Laura, adaptada por la NBC en Estados Unidos bajo el título The Mysteries of Laura (NBC, 2014- 2016) Metodología. Para alcanzar estos objetivos, se ha realizado un análisis de las series españolas adaptadas en mercados extranjeros durante el 2005-2017, así como una entrevista a los dos guionistas españoles creadores de Los Misterios de Laura y el análisis de la biblia de la serie objeto de estudio. Conclusiones y discusión. Este trabajo resalta la relevancia de la fase de desarrollo o diseño de la idea donde se trabajan la adecuación del concepto, el tono y el diseño de personajes como claves en el proceso de adaptación de una serie española en el extranjero.
The Future of Biosimilars
Authors: El-Bakry L 
Published: April 2018

<p>Biosimilars are to Biologic products what generic drugs are to chemical products, a more affordable solution to the increasing drug pricing without sacrificing the quality of the treatment.There is much debate in the health care industry as to whether Biosimilars will deliver on the same success achieved by the generic products, which can amount to up to 80% in some cases. It is my view though that Biosimilars provide a viable path to cost reduction, quality improvement and affordable accessibility to medication. In fact, the introduction of lower costs Biologics as intended by the Biosimilar market will force competition within the therapeutics treatment market that will both exertpricing pressure as well as inspire innovation in the entire ecosystem. </p>
Clinical Parameters and CRP Levels in Generalized Aggressive Periodontitis Patient: A Case Report
Authors: Balcı Yüce Hatice , Uçan Yarkaç Fatma , Tulu Feyza 
Published: April 2018

Aim: Generalized aggressive periodontitis (G-AgP) is the most severe and destructive form of periodontitis.It usually starts under the age of 30 and it is difficult to recover tissue health with sole periodontal treatment. In this case was to evaluate effect of full-mouth ozone treatment on clinical parameters and blood CRP levels in a G-AgP patient.
Methodology: A 23 year-old male patient was diagnosed as G-AgP.Clinical attachment levels (CAL), plaque index (PI), gingival index (GI), bleeding on probing (BoP) and blood C-reactive protein (CRP) levels were recorded.Full mouth scaling and root planning and ozone application were performed.
Results: Baseline mean full-mouth PI,GI scores and CAL were 3,2 and 5.2mm respectively. 42% of sites showed a CAL of 4-6mm and 26% showed ≥7mm. 72% of the sites exhibited BOP.15 teeth had CAL ≥6mm. After treatments, PI and GI scores were both 1.0. 19% of sites had 4-6mm and 16% of sites were ≥7mm CAL; 12% exhibited BOP. Six teeth had CAL ≥6mm.Baseline CRP was 9 mg/dL and increased to 34 during treatments and decreased to 2 mg/dL after 4 weeks.
Conclusion: Within limitations of this case report, it could be suggested that monitoring CRP and subgingival ozone application might be beneficial in treating GAgP.
Patients experience major changes in life and significant others struggle with caregiving during the course of incurable cancer: a systematic review and meta-synthesis
Authors: Madsen Rikke , Birkelund Regner , Uhrenfeldt Lisbeth 
Published: April 2018

Aim: The aim of this review was to explore experiences of patients and significant others concerning existential, psychosocial and organisational transitions during the course of incurable cancer.Methods: The search was based on 5 databases (PubMed, CINAHL, Scopus, PsycInfo and Embase) and 50 studies were finally included and critically appraised. The review was inspired by the methods of Joanna Briggs Institute, Kvale and Brinkmann and illustrated with effect size, inspired by Sandelowski and Barroso.Results: Based on experiences from 496 patients and 320 significant others, 3 main themes with 3 subthemes each were identified and, from these, a meta-synthesis was developed. Patients experience major changes in life and significant others struggle with caregiving during the course of incurable cancer. Main themes: 1. Patients living with incurable cancer experience major changes in life; 2. Patients’ experiences of both living and dying; 3. Significant others living and loosing. Relating findings to the theory of Irvin D. Yalom revealed that patients and significant others experience transitioning into living most of life in an ontological mode of existence.Conclusion: This review underlines the complexity within planning individualised palliative care and contributes with evidence-based knowledge relevant to healthcare professionals in palliative cancer care.
« L’impuissance de la victoire » comme symbole d’un changement dans la nature de la guerre ?
Authors: Schu Adrien 
Published: April 2018

L’objectif de cette contribution est de présenter et discuter une thèse, apparue à la suite des interventions américaines en Afghanistan (2001) et en Irak (2003), qui prétend que la relation entre la victoire militaire et le retour à la paix aurait été complètement bouleversée. Selon les tenants de cette thèse, la victoire militaire entraînait autrefois le renoncement automatique du belligérant défait et, consécutivement, la fin des hostilités. Cependant, ils constatent que tel n’est plus le cas aujourd’hui et en concluent qu’un changement profond dans la nature même de la guerre aurait récemment eu lieu. Les auteurs que nous nous proposons d’étudier livrent ainsi une contribution originale s’insérant pleinement dans le courant des « nouvelles guerres ». Nous critiquerons néanmoins leur thèse, soulignant ses lacunes conceptuelles, historiques et théoriques et montrerons que la victoire militaire, telle que l’entendent ces auteurs, n’a jamais eu pour conséquence inévitable le retour à la paix.
Prólogo: Schopenhauer é um verdadeiro discípulo de Kant?
Authors: Lúcia Cacciola Maria 
Published: April 2018

A pergunta que orienta esta reflexão nos conduz ao cerne da postura crítica de Schopenhauer em relação a Kant. Se, por um lado, o filósofo de Frankfurt nos oferece uma interpretação peculiar que parece se afastar do pensamento kantiano, por outro, parece ter como intenção apenas retificar os erros que considera estarem contidos nessa filosofia que, para Schopenhauer, não esclarece devidamente a relação entre intuição e conceito. A estrutura do pensamento kantiano, a sua arquitetônica, é rejeitada por Schopenhauer como um retorno ao racionalismo escolástico, que se mostra na supremacia da ordenação lógica do pensamento em relação à efetividade. Isso se reflete no que Schopenhauer denomina “o amor à simetria” de Kant, que o faz montar a sua tábua de categorias simétricas, esquecendo-se da autonomia do objeto da intuição, a ser garantida, segundo o filósofo de Frankfurt, pelo papel que o entendimento exerce na intuição imediata dos objetos.
Atrial Flutter With Exercise-Induced 1:1 Atrioventricular Conduction
Authors: Burkhart Ryan , Gerasimon Gregg 
Published: April 2018

Abstract
Typical atrial flutter is a common atrial tachyarrhythmia. Symptoms are typically related to the rate of ventricular response. Although atrial flutter with 1:1 atrioventricular conduction is rare, it is important to recognize because it may precipitate rapid hemodynamic compromise. The authors present a case of exercise-induced 1:1 atrioventricular conduction in a patient with typical atrial flutter.
Behavior and biocompatibility of rabbit bone marrow mesenchymal stem cells with bacterial cellulose membrane
Authors: Silva Marcello de Alencar , Leite Yulla Klinger de Carvalho , Carvalho Camila Ernanda Sousa de , Feitosa Matheus Levi Tajra , Alves Michel Muálem de Moraes , Carvalho Fernando Aécio de Amorim , Neto Bartolomeu Cruz Viana , Miglino Maria Angélica , Jozala Angela Faustino , Carvalho Maria Acelina Martins de 
Published: April 2018

Background
Tissue engineering has been shown to exhibit great potential for the creation of biomaterials capable of developing into functional tissues. Cellular expansion and integration depends on the quality and surface-determinant factors of the scaffold, which are required for successful biological implants. The objective of this research was to characterize and evaluate the in vitro characteristics of rabbit bone marrow mesenchymal stem cells (BM-MSCs) associated with a bacterial cellulose membrane (BCM). We assessed the adhesion, expansion, and integration of the biomaterial as well as its ability to induce macrophage activation. Finally, we evaluated the cytotoxicity and toxicity of the BCM.

Methods
Samples of rabbit bone marrow were collected. Mesenchymal stem cells were isolated from medullary aspirates to establish fibroblast colony-forming unit assay. Osteogenic, chondrogenic, and adipogenic differentiation was performed. Integration with the BCM was assessed by scanning electron microscopy at 1, 7, and 14 days. Cytotoxicity was assessed via the production of nitric oxide, and BCM toxicity was assessed with the MTT assay; phagocytic activity was also determined.

Results
The fibroblastoid colony-forming unit (CFU-F) assay showed cells with a fibroblastoid morphology organized into colonies, and distributed across the culture area surface. In the growth curve, two distinct phases, lag and log phase, were observed at 15 days. Multipotentiality of the cells was evident after induction of osteogenic, chondrogenic, and adipogenic lineages. Regarding the BM-MSCs’ bioelectrical integration with the BCM, BM-MSCs were anchored in the BCM in the first 24 h. On day 7 of culture, the cytoplasm was scattered, and on day 14, the cells were fully integrated with the biomaterial. We also observed significant macrophage activation; analysis of the MTT assay and the concentration of nitric oxide revealed no cytotoxicity of the biomaterial.

Conclusion
The BCM allowed the expansion and biointegration of bone marrow progenitor cells with a stable cytotoxic profile, thus presenting itself as a biomaterial with potential for tissue engineering.
Comparing CMIP-3 and CMIP-5 climate projections on flooding estimation of Devils Lake of North Dakota, USA
Authors: Kharel Gehendra , Kirilenko Andrei 
Published: April 2018

BackgroundWater level fluctuations in endorheic lakes are highly susceptible to even slight changes in climate and land use. Devils Lake (DL) in North Dakota, USA is an endorheic system that has undergone multi-decade flooding driven by changes in regional climate. Flooding mitigation strategies have centered on the release of lake water to a nearby river system through artificial outlets, resulting in legal challenges and environmental concerns related to water quality, downstream flooding, species migration, stakeholder opposition, and transboundary water conflicts between the US and Canada. Despite these drawbacks, running outlets would result in low overspill risks in the next 30 years.MethodsIn this study we evaluated the efficacy of this outlet-based mitigation strategy under scenarios based on the latest IPCC future climate projections. We used the Coupled Model Intercomparison Project CMIP-5 weather patterns from 17 general circulation models (GCMs) obtained under four representative concentration pathways (RCP) scenarios and downscaled to the DL region. Then, we simulated the changes in lake water levels using the soil and water assessment tool based hydrological model of the watershed. We estimated the probability of future flood risks under those scenarios and compared those with previously estimated overspill risks under the CMIP-3 climate.ResultsThe CMIP-5 ensemble projected a mean annual temperature of 5.78 °C and mean daily precipitation of 1.42 mm/day; both are higher than the existing CMIP-3 future estimates of 4.98 °C and 1.40 mm/day, respectively. The increased precipitation and higher temperature resulted in a significant increase of DL’s overspill risks: 24.4–47.1% without release from outlets and 3.5–14.4% even if the outlets are operated at their combined full 17 m3/s capacity.DiscussionThe modeled increases in overspill risks indicate a greater frequency of water releases through the artificial outlets. Future risk mitigation management should include providing a flood warning signal to local resource managers, and tasking policy makers to identify additional solution measures such as land use management in the upper watershed to mitigate DL’s flooding.
Movement velocity in the chair squat is associated with measures of functional capacity and cognition in elderly people at low risk of fall
Authors: Balsalobre-Fernández Carlos , Cordón Ángel , Unquiles Nazaret , Muñoz-García Daniel 
Published: April 2018

Background
The purpose of this study was to analyze the relationships between muscular performance consisting of a single repetition on the chair squat exercise (CSQ) and different measures of functional capacity, balance, quality of life and cognitive status in older adults.

Methods
A total of 40 participants (22 women, 18 men; age = 72.2 ± 4.9 years) joined the investigation. Muscular performance was assessed by measuring movement velocity in the CSQ with no external load using a validated smartphone application (PowerLift for iOS). Functional capacity, balance, quality of life and cognitive status were evaluated using the hand-grip strength (HGS) test, the Berg-scale, the EuroQol 5D (EQ-5D) and the Mini mental state examination questionnaire (MMSE). Finally, participants were divided into two subgroups (N = 20) according to their velocity in the CSQ exercise.

Results
Positive correlations were obtained between movement velocity in the CSQ and HGS (r = 0.76, p < 0.001), the Berg-scale (r = 0.65, p < 0.001), the EQ-5D (r = 0.34, p = 0.03) and the MMSE (r = 0.36, p = 0.02). Participants in the fastest subgroup showed very likely higher scores in the Berg-scale (ES = 1.15) and the HGS (ES = 1.79), as well as likely higher scores in the MMSE scale (ES = 0.69).

Discussion
These results could have potential clinical relevance as they support the use of a time-efficient, non-fatiguing test of muscular performance (i.e., the CSQ) to evaluate functional capacity and mental cognition in older adults.
MARSICO, G.; KOMATSU, K.; IANNACCONE, A. Crossing Boundaries: Intercontextual Dynamics Between Family and School. Charlotte, NC: Information Age Publishing (IAP). 2013.
Authors: Nascimento Verônica Gomes , Dória André Luís Prado , Dazzani Maria Virginia Machado 
Published: April 2018

Crossing Boundaries: Intercontextual Dynamics Between Family and School é uma coletânea publicada em 2013 pela Information Age Publishing (IAP), organizada por Giuseppina Marsico (Universidade de Salerno), Koji Komatsu (Universidade Osaka Kyoiku) e Antonio Iannaccone (Universidade de Neuchâtel). O livro está organizado em duas seções, com cinco capítulos (1-5) na primeira seção e seis capítulos (6-11) na segunda. A primeira seção é intitulada Explorations of Regulatory Dynamics Taking Place During the Encounters of the Two Microsystems e a segunda Analyses of the Representations’ System Produced by the Actors in One Context (Family) Towards the Other Microsystem (School). Na última seção estão inseridos, ainda, três capítulos finais (Commentary; General Conclusion: Moving Between the Social Spaces: Conditions for Boundaries Crossing; e About the contributor).
A coletânea representa uma aproximação, um convite para o estudo dos processos educacionais a partir da perspectiva da psicologia cultural. O objetivo central da coletânea é analisar aquilo que acontece na zona de contato (border) entre a cultura familiar e a cultura escolar. O livro apresenta uma discussão sobre as fronteiras existentes entre esses diferentes contextos educacionais. Os autores propõem uma reflexão sobre os variados discursos que surgem na zona de fronteira e sobre o movimento de atravessá-las, observando o que acontece na vida cotidiana dos atores envolvidos. Ao analisarem o movimento entre os espaços sociais e os processos dinâmicos que acompanham o diálogo entre a família e escola, os autores recorrem aos diversos conceitos da psicologia cultural.