bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cotilos de doble movilidad. Uso para la revisión femoral aislada de prótesis de cadera con fricción metal/metal con cabezas grandes. [Use of dual mobility acetabular cups for isolated femoral revision of metal on metal hip resurfacing arthroplasty using larger femoral heads]
Authors: Valdez Sebastián Enrique 
Published: February 2019

Los recambios de cadera con cabezas metálicas grandes provocan una mayor tasa de complicaciones, principalmente asociadas al retiro del componente acetabular, como al par fricción utilizado. En casos determinados, pueden realizarse revisiones femorales aisladas, conservando la copa acetabular, disminuyendo la morbilidad quirúrgica.Presentamos un caso tratado exitosamente con una copa de doble movilidad, en un paciente con una prótesis de superficie con un seudotumor que generó dolor e inestabilidad.El conocimiento de esta técnica quirúrgica permite al cirujano de cadera resolver problemas complejos de forma sencilla y segura, con una baja tasa de complicaciones. AbstractLarge head metal on metal hip arthroplasty revision has a significant complication rate, mainly related to the removal of the acetabular component, as well as to the friction pair used. In some cases, an isolated femoral revision can be made, sparing the acetabular cup and, thus, decreasing surgical morbidity.This paper discusses a case successfully treated with a dual mobility acetabular cup in a patient with a resurfacing hip replacement and a pseudotumor that caused pain and instability.Mastering this surgical approach allows hip surgeons to solve complex problems in a simple and safe manner, and with a low complication rate.
Extremidad superior gravemente lesionada. Reporte de un caso clínico. [Mangled upper extremity. Case report]
Authors: Sánchez Villanueva Francisco Javier , Suárez Villalobos Pablo , Grau Núñez Luis , Sepúlveda Oviedo Matías 
Published: February 2019

Se presenta un paciente con una extremidad superior gravemente lesionada por arma de fuego. Inicialmente fue tratado con múltiples limpiezas quirúrgicas y colocación de tutor externo AO. El tratamiento definitivo consistió en tutor externo monolateral, además de injerto estructural de cresta ilíaca. Durante el manejo inicial, se detecta lesión del nervio radial, con nervio en continuidad. Dado el proceso cicatricial y la infección de partes blandas, no se logra manejar en la etapa aguda. Posteriormente se realizan transferencias tendinosas para nervio radial. La evolución fue favorable y la función de la extremidad superior resultó satisfactoria. Se comunica este caso debido a su complejo manejo a causa de las lesiones óseas, neurovasculares, cutáneas y de partes blandas. AbstractWe present a patient with a severely injured upper extremity due to a shotgun. Patient was initially managed with multiple surgical debridements and an AO external fixator.Final treatment was performed with a monolateral external fixator, in addition to an iliac crest structural bone graft. During initial management, a radial nerve injury was observed;the nerve was intact, though devitalized. Given the scarring process and soft tissue infection, treatment was performed in the acute phase. Subsequently, tendon transfers were made to treat a radial nerve injury. Patient evolved favorably and regained adequate function of the upper extremity.This case is presented due to its complex management due to bone, neurovascular, skin, and soft tissue involvement.
Bacteriemia por <i>Staphylococcus aureus</i>. Un abordaje inicial simplificado.
Authors: Montero Chacón Luis Bolivar , Dobles Ramírez Carlos , Salas Segura Donato A. 
Published: February 2019

El Staphylococcus aureus es un germen causante de infecciones severas que ponen en riesgo la vida de los pacientes. La bacteriemia constituye una de las presentaciones más graves de este tipo de infecciones, con un abordaje y tratamiento que a menudo resultan complejos e incompletos. La selección de la terapia antibiótica, la duración de la misma y los niveles séricos del antibiótico, a menudo se determinan de forma empírica y especulativa; llevando con frecuencia a fallas terapéuticas. El uso concomitante de oxacilina y vancomicina, mientras se obtiene el perfil de sensibilidad, es una buena opción para iniciar el tratamiento.
High incidence of multiresistant bacterial isolates from bloodstream infections in trauma emergency department and intensive care unit in Serbia
Authors: Djuric Olivera , Markovic-Denic Ljiljana , Jovanovic Bojan , Bumbasirevic Vesna 
Published: February 2019

We investigated the incidence of bloodstream infections (BSIs) in trauma emergency department (ED) and intensive care unit (ICU), to assess ED- and ICU-related predictors of BSI and to describe the most common bacteria causing BSI and their antimicrobial resistance markers. A prospective study was conducted in two trauma ICUs of the ED of Clinical Center of Serbia. Overall, 62 BSIs were diagnosed in 406 patients, of which 13 were catheter-related BSI (3.0/1,000 CVC-days) and 30 BSIs of unknown origin, while 15% were attributed to ED CVC exposure. Lactate ≥2 mmol/L and SOFA score were independent ED-related predictors of BSI, while CVC in place for >7 days and mechanical ventilation >7 days were significant ICU-related predictors. The most common bacteria recovered wereAcinetobacterspp.,Klebsiellaspp., andPseudomonas aeruginosa.AllStaphylococcus aureusand coagulase-negative staphylococci isolates were methicillin-resistant, whereas 66% ofEnterococcusspp. were vancomycin-resistant. All isolates ofEnterobacteriaceaewere resistant to third-generation cephalosporins, whereas 87.5% ofP. aeruginosaand 95.8% ofAcinetobacterspp. isolates were resistant to carbapenems. ED BSI contributes substantially to overall ICU incidence of BSI. Lactate level and SOFA score can help to identify patients with higher risk of developing BSI. Better overall and CVC-specific control measures in patients with trauma are needed.
Evidencias mineralógicas y geoquímicas de las manifestaciones de hierro hospedadas en La Unidad Riodacita de los Tábanos sector de Corral de Piedras, San Juan del Cesar, La Guajira/Mineralogical and geochemical evidence of the iron manifestations...
Authors: Moscote Daza Yesica Paola 
Published: February 2019

El sector minero constituye un aspecto transcendental en el ámbito socioeconómico del departamento de La Guajira debido al crecimiento exponencial de los ingresos por concepto de las explotaciones y exportaciones en el caso del Carbón y Gas. En el sur del departamento en el corregimiento Corral de Piedras perteneciente al municipio de San Juan de Cesar (La Guajira), afloran llamativas manifestaciones metálicas inexploradas actualmente, dirigiendo así este artículo en la caracterización, descripción y concentración porcentual de los minerales presentes en esas mineralizaciones, se tomaron para este investigación cuatro (4) muestras, (YJ-01, YJ-02, YJ-03 y YJ-05) cuyas características mineralógicas, aspectos microestructurales y morfológicos fueron detallados con el microscopio electrónico de Barrido y espectroscopia por Dispersión de Energía (SEM/EDS), el análisis de fluorescencia de rayos X (FRX) en el rango de sodio (Na) a Uranio (U) permitió la caracterización química de los minerales considerando una matriz oxidada en razón de la ganancia de oxígeno, obteniéndose interesantes concentraciones de Fe entre 54.80% - 48.31% y Fe2O3 desde 78.35% - 69.07%, la difracción de rayos X (DRX) proporciono información cualitativa y cuantitativa sobre la composición elemental, mediante la comparación de los perfiles de difracción, y las fases encontradas con el refinamiento por el Método de Rietveld en los perfiles observados en las muestras, describiendo cada una de las fases cristalinas presentes, estas fueron reportadas por la base de datos PDF-2 del International Centre for Diffraction Data (ICDD) cuyos registros identifican la magnetita, hematita, cuarzo y actinolita calentada como cristalinos principales, con concentraciones entre 72.7% y 58.1%.
Structural, spectroscopic and optical properties of 4-(6- (dimethylamino)benzo[d]thiazol/Propiedades estructurales, espectroscópicas y ópticas de 4-(6-(dimetilamino)benzo[d]tiazol-2-il)benzonitrilo como modelo de sistema D-E-A por métodos computacionales
Authors: Fernández Vega Lauren Vanessa , Pérez Gamboa Alfredo , Ruidiaz Buelvas María Angélica , Pérez Hincapié Liddier 
Published: February 2019

Por medio del estudio computacional de 4-(6-(dimetilamino)benzo[d]tiazol-2-il)benzonitrilo se realizó la optimización de la geometría molecular, donde a partir de la estructura más estable energéticamente se obtuvieron las propiedades espectroscópicas de UV-vis, IR, RMN 1H, RMN 13C, la ocupación e hibridación por medio del análisis NBO, de igual forma, se determinaron sus propiedades electrónicas (orbitales HOMO-LUMO) y de óptica no lineal (ONL). Por último, se estudió la reactividad mediante el mapa de potencial electrostático (MEP) y los descriptores de reactividad global y local (funciones de Fukui). Todos los cálculos se realizaron al nivel DFT/cam-B3LYP/6-31G(2d) empleando el programa Gaussian09W y GaussView 5.08como interfaz gráfica. Los resultados fueron comparados con los valores experimentales descritos para fragmentos estructurales análogos de la literatura conservando el mismo ambiente químico, obteniendo una buena correlación.
Premature Ventricular Contraction in Children
Authors: Baranov Alexander A. , Vasichkina Elena S. , Ildarova Roza A. , Lebedev Dmitry S. , Namazova-Baranova Leyla S. , Pokushalov Evgeniy A. , Popov Sergey V. , Termosesov Sergey A. , Shkolnikova Maria A. 
Published: February 2019

The article presents updated data on the problem of premature ventricular contractions in children based on the clinical guidelines of the Russian Society of Cardiology and the Union of Pediatricians of Russia for the diagnosis, treatment and management of pediatric patients with premature ventricular contraction. The issues of diagnosis and treatment based on the principles of evidence-based medicine as well as important aspects of prevention of exacerbations and follow-up have been clarified in detail. The criteria for assessing the quality of care for patients with premature ventricular contractions have been presented.CONFLICT OF INTEREST. Not declared.
The Function of Large Vessels in Normal-Weight and Overweight Children With Psoriasis During Methotrexate Therapy
Authors: Murashkin Nikolay N. , Kogevnikova Olga V. , Materikin Alexander I. 
Published: February 2019

Background.In recent years, the opinion has been established that skin manifestations of psoriasis are associated with the damage of other organs and systems, and that psoriatic lesions have a systemic nature, and therefore the term ‘psoriatic disease’ is increasingly used in scientific literature. Among psoriasis comorbidities, metabolic disorders and cardiovascular diseases are of particular clinical importance.Our aim wasto study the effect of systemic cytostatic therapy with methotrexate on the remodelling processes of large vessels in children with psoriasis who have normal and increased body mass index.Methods.The primary data was collected by extracting data from medical records and case follow-up records. The subsequent accumulation, storage, grouping and primary sorting of research data were carried out using a personal computer and Excel application package. Clinical evaluation of the severity of psoriasis and skin lesions was assessed by calculating the PASI index. Non-invasive oscillometric arteriography was performed on a portable ArterioGraph (TensioMed Ltd, Hungary).Results.A direct significant correlation has been established between the revealed impairments of the function of large arteries and the indicators of fat metabolism, the severity of psoriasis and body mass index. During the systemic pathogenetic cytostatic therapy with methotrexate, a significant positive dynamics of the function parameters of large arteries was revealed in children with psoriasis who have both normal and increased body mass index.Conclusion.The undertaken studies showed that methotrexate is an effective and safe agent for treating psoriasis in children aged from 3 to 18 years, has a positive effect on the function of large vessels.Nikolay N. Murashkin — receiving research funding from pharmaceutical companies Jansen, Eli Lilly. Receiving fees for scientific advice from Galderma, Pierre Fabre, Bayer, Astellas, Libriderm.Alexander I. Materikin — receiving research funding from pharmaceutical company Eli Lilly. Receiving fees for scientific advice from Bioderma, Libriderm.
Symptoms of Oesophageal Affection in Children With Scleroderma According to Mano-Impedancemetry: A Case Series
Authors: Stepanyan Marina Ju. , Komarova Elena V. , Murashkin Nikolay N. , Alexeeva Ekaterina I. 
Published: February 2019

Background.Currently, scleroderma is a rather rare disease, including among children. Despite the growing interest of investigators in this pathology, the problem of diagnosing oesophageal affection in various forms of systemic sclerosis remains under-investigated since endoscopic data does not provide a complete picture of the oesophageal function. Currently, mano-impedancemetry (MIP) is the leading method in Europe for determining the oesophageal function, including in children with scleroderma; in the Russian Federation, it is used only in adults. Proper and timely evaluation of the oesophageal motility state will allow not only to expand our understanding of the disease pathogenesis but also to determine the efficacy of the initiated therapy and to give practice suggestions in terms of treatment tactics in the early stages of the disease.Our aim wasto determine the possibilities of mano-impedancemetry for diagnosing oesophageal affection in juvenile scleroderma.Patients and Methods.The study included children with juvenile scleroderma taken to the department of rheumatology and dermatology from June to August 2016. To identify oesophageal function disorders, all patients underwent high-resolution manometry in combination with impedancemetry.Results.A decrease in the distal oesophageal contraction amplitude in more than 30% of “wet” swallows was found in 2 of 7 children with juvenile systemic scleroderma and in one of 6 children with juvenile focal scleroderma. All 13 patients had peristaltic waves in the distal oesophagus with an amplitude of <30 mm Hg. They had interrupted peristalsis, in which the peristaltic wave did not go through the entire length of the oesophagus; one of these patients showed a simultaneous contraction with an amplitude of <30 mm Hg. All children (n=13) showed a positive correlation (r= 0.021) between the systemic disease and impaired motility (р=0.021).Conclusion.Despite the clinical and laboratory methods for diagnosing scleroderma, the data of oesophageal mano-impedancemetry is an important criterion, primarily for the differential diagnosis of systemic and focal scleroderma, and assists in the early initiation of therapy for oesophageal motility disorders.Marina Ju. Stepanyan, Ekaterina I. Alexeeva, Elena V. Komarova confirmed the absence of a reportable conflict of interest.Ekaterina I. Alexeeva — receiving research grants from Pfizer, Roche, Centocor, Novartis.Nikolay N. Murashkin — receiving research funding from pharmaceutical companies Jansen, Eli Lilly. Receiving fees for scientific advice from Galderma, Pierre Fabre, Bayer, Astellas, Libriderm.
Genesis and Substance in Posidonius’ Stoicism
Authors: Murtinho Braga Boechat Eduardo 
Published: February 2019

The Posidonian fragment regarding the process of genesis as described by Arius Dydimus (Epitomefr.27 Diels) turns up twice in Stobaeus’ Eclogae. The passage occurs in a section (I. 20) entitled On Generation and Destructionwhich is mostly concerned with whether the cosmos is destructible. It is followed by a reference to criticism of Mnesarchus, the pupil of Panaeitus. The fragment recurs in Stobaeus at the end of I. 17; this is the chapter which contains Chrysippus’ orthodox classification of mixtures as juxtaposition, fusion and blending (παραθέσει,συγχύσει,κρᾶσιν). As we shall see, there is substantial evidence that Posidonius revised the Stoic position and proposed a new concept of genesis.
Violencia política y relatos desde la dimensión subjetiva
Authors: Herrera Martha Cecilia , Olaya Vladimir 
Published: February 2019

En Colombia se afirma que es tiempo de memoria para aludir al posicionamiento en la agenda pública de los asuntos de violencia política acaecidos en nuestra historia reciente, lo cual ha dado pie al desarrollo de investigaciones académicas y al diseño de políticas públicas tendientes al esclarecimiento de lo acontecido y de sus posibles soluciones. Desde este horizonte el artículo reflexiona sobre la importancia de la literatura biográfica y testimonial y su pertinencia dentro de la investigación histórica para el abordaje de este tipo de problemáticas. Como parte de este propósito se analiza uno de los relatos testimoniales recolectados en una investigación llevada a cabo en torno a la configuración de subjetividades en contextos de violencia política, indicando como este tipo de fuentes al tiempo que habilitan al sujeto corriente como participante de un momento histórico determinado, revelan, a su vez, los estrechos lazos existentes entre individuo y sociedad.
Identification and In Silico Analysis of Anti Inflammation and Anti Oxidant Potentials of Polyphenol Compounds in Methanol Extract of Tamarindus indica Seeds
Authors: Narwanto Muhammad Ihwan , Rahayu Masruroh , Soeharto Setyawati , Nurdiana Nurdiana , Widodo Moch. Aris 
Published: February 2019

ABSTRACT
Indonesia has abundant stock of Tamarindus indica seeds, but it is not yet utilized maximally, especially in medical field. Tamarindus indica seeds have high content of polyphenols compound. No reseacrh is supported by in silico data on polyphenol compound in Tamarindus indica seeds extract. Polyphenols compound can be utilized as a neuroprotective agent. This research aims to measure polyphenols concentration in methanol Tamarindus indica seeds extract and determine the anti inflammation and antioxidant potential of each polyphenol compound in methanol Tamarindus indica seeds extract by in silico method. The extraction of Tamarindus seeds used maceration method and methanol as solvent. Identification and measurement of polyphenols compound applied HLPC-MS. PyMol and Pyrx tools were used for in silico analysis. Extract recidu was obtained from methanol Tamarindus indica seeds as much as 12%w/v. HPLC-MS anaysis mentioned that levels of procyanidin B2, myricentin and caffeic acid were respectively 38.850 mg/kg, 5.845 mg/kg and 260 mg/kg. The highest anti inflammatory potential was owned by myricentin than caffeic acid, while the lowest potential in procyanidin B2. Furthermore, the highest antioxidant potential was sequentially in myricentin, procyanidin B2 and caffeic acid. It is very possible to utilize methanol Tamarindus indica seeds extract for preventing neurodegenerative diseases since its pathogenesis involves inflammatory and stress oxidative process.
Keywords : Tamarindus indica, myricetin, procyanidin B2, caffeic acid, anti inflammatory, antioxidant
Effect of Soyflour (Glycine max L.) Hepatoprotector Activity on Liver MDA Level in Male Wistar Rat Induced by Diazinon
Authors: Himah Sofi Aliyatul , Wisudanti Desie Dwi , Fatmawati Heni 
Published: February 2019

Diazinon is metabolized in liver becomes diazoxon, an active metabolite form that can cause free radical raisingthat leads to lipid peroxidation. The result of lipid peroxidation is MDA. Soyflour has higher isoflavones than theother processed food of Glycine max L.This isoflavones donate its electron and hydrogen atom in lipidperoxidation so it can block the lipid peroxidation. The aim of this experiment is to investigate the effect of soyflour on MDA hepar level increase of male wistar rat induced by diazinon. The sample are divided into 5 groupswhich are Kn, K(-) group induced by diazinon 40mg/kgBW, K1, K2, K3 group given with soy flour 10%, 15%, and20% orally, then induced by diazinon 40 mg/kgBW. MDA liver measured on the day 34th with MDA-TBAmethode which has pink colour and measured by spectrofotometer. Average of liver MDA levels is Kn 6,35μg/mL; K(-) 9,23 μg/mL; K1 8,85 μg/mL; K2 7,88 μg/mL; K3 7,04 μg/mL. One way ANOVA and Post hoc LSDshowed significantly different (p<0,05). Pearson correlation showed strong negative correlation.
Keywords: Diazinon, Diazoxon, MDA, Soyflour, Glycine max L., antioxidant
Validating the National Violent Death Reporting System as a Source of Data on Fatal Shootings of Civilians by Law Enforcement Officers
Authors: Conner Andrew , Azrael Deborah , Lyons Vivian H. , Barber Catherine , Miller Matthew 
Published: February 2019

Objectives. To evaluate the National Violent Death Reporting System (NVDRS) as a surveillance system for fatal shootings of civilians by law enforcement in the United States. Methods. We cross-linked individual-level mortality data from the 2015 NVDRS and 5 open-source data sets ( FatalEncounters.org , Mapping Police Violence, the Guardian’s “The Counted,” Gun Violence Archive, and The Washington Post’s “Fatal Force Database”). Using the comprehensive cross-linked data set, we assessed the proportion of study-identified fatal police shootings that were captured by NVDRS, overall and by state, and by each open-source data set. Results. There were 404 unique study-identified fatal shootings by law enforcement in the 27 states for which data were available from NVDRS, 393 (97%) of which were captured in NVDRS. The proportion of shootings captured by NVDRS varied only slightly by state. Conclusions. The NVDRS provides a comprehensive count of fatal police shootings. Public Health Implications. Expanding NVDRS to all 50 states would provide comprehensive counts of fatal police shootings and detailed circumstantial information about these deaths at the national level. Open-source data can continue to provide real-time data collection as well as more complete information about nonfirearm officer-involved deaths.
A Brief History of the Prevention and Public Health Fund: Implications for Public Health Advocates
Authors: Fraser Michael R. 
Published: February 2019

The nation’s first broad-based, mandatory investment in public health and prevention, the Prevention and Public Health Fund (the Fund), has had a brief and controversial history. Advocates for the Fund have had to defend it from both Democratic and Republican threats, including being used as an offset for administration priorities, and from congressional efforts to repeal and replace the Patient Protection and Affordable Care Act. Lessons learned from efforts to sustain the Fund are instructive in addressing current and future challenges faced by advocates for public health programs and prevention policies.