bluuebunny/crossref_metadata_2025_split huggingface dataset:
Probiotics and eating disorders: a systematic review of humans and animal model studies
Authors: Bahari Hossein , Akhgarjand Camellia , Mirmohammadali Seyedeh Nooshan , Malekahmadi Mahsa 
Published: November 2024

Abstract
Background
Eating disorders are complex mental health conditions that significantly impact physical and mental well-being. Current research suggests a potential link between eating disorders and the gut microbiota, highlighting the role of gut-brain communication and its influence on nutrient absorption. Probiotics, which are beneficial bacteria, have shown promise in modulating the gut microbiota and may offer complementary interventions in the treatment of eating disorders.

Methods
A comprehensive search was conducted in electronic databases, including PubMed/Medline, Scopus, and Web of Science, from inception to January 2024 to analyze the existing literature on the effects of probiotic supplementation in eating disorders. The search strategy included terms related to probiotics, prebiotics, eating disorders, and food addiction. The human studies were assessed for risk of bias using the Cochrane tool. The quality of animal studies was evaluated using the risk of bias (RoB) tool from the Systematic Review Centre for Laboratory Animal Experimentation.

Results
Of the 417 papers, 12 eligible studies were included comprising five animal and seven clinical studies. Clinical trials ranged from 10 to 20 weeks and were randomized and parallel-arm design. The included studies varied in terms of sample characteristics, intervention types, and outcome measures. Preliminary findings suggest that probiotics may influence gut microbiota composition and may offer support in the treatment of eating disorders.

Conclusions
The reviewed studies showed that probiotic supplementation may have a role in reducing food addiction and binge eating, and enhancing satiety, regulating food intake as well as positively affecting mood. However, further studies with better quality and larger sample size are needed to further validate these findings.
Rapid-repeat time-lapse vertical seismic profile imaging of CO2 injection
Authors: Cai Xiaohui , Hu Qi , Innanen Kristopher A. , Keating Scott D. , Eaid Matthew V. , Macquet Marie , Lawton Donald C. 
Published: November 2024

In a carbon capture and storage (CCS) project, monitoring CO2 during the injection period is crucial for ensuring the safety and effectiveness of the injection process. The real-time observation of CO2 behavior allows for adjustments to the injection parameters to enhance performance and enables the refinement of the reservoir simulation models to predict plume migration accurately. Achieving this with seismic surveys requires significantly shorter intervals between the surveys compared with the conventional monthly or yearly timescales. This study aims to identify an effective seismic monitoring method, encompassing acquisition design and an imaging technique, for capturing the short-term, dynamic subsurface changes resulting from CO2 injection. We present images generated through elastic full-waveform inversion applied to rapidly repeated time-lapse vertical seismic profile (VSP) field data. The data are acquired using a fixed source shooting across an injection plume at approximately 15 min intervals over several days. These images, created from a combination of sparse geophone data and densely distributed acoustic sensing (DAS) data, provide clear snapshots of transient subsurface changes near the injection well. The results are further validated using a synthetic inversion experiment, demonstrating that the combined geophone and DAS-VSP approach offers a cost-effective and informative monitoring solution for CCS projects.
Oxaliplatin-Based Versus Alkylating Agent in Neuroendocrine Tumors According to the O
6
-Methylguanine-DNA Methyltransferase Status: A Randomized Phase II Study (MGMT-NET)
Authors: Walter Thomas , Lecomte Thierry , Hadoux Julien , Niccoli Patricia , Saban-Roche Léa , Gaye Elisabeth , Guimbaud Rosine , Baconnier Mathieu , Hautefeuille Vincent , Do Cao Christine , Petorin Caroline , Hentic Olivia , Perrier Marine , Aparicio Thomas , Scoazec Jean-Yves , Bonjour Maxime , Gibert Benjamin , Hervieu Valérie , Poncet Delphine , Barritault Marc , Gerard Laura , Durand Alice ,   on behalf of the “Groupe d’étude des tumeurs endocrines (GTE)” and the French ENDOCAN-RENATEN network
Published: November 2024

PURPOSE

Alkylating agents (ALKY) are the main chemotherapies used for advanced neuroendocrine tumors (NETs). O
6
-Methylguanine-DNA methyltransferase (MGMT) status, as proficient (p) or deficient (d), may predict the response to ALKY.

PATIENTS AND METHODS

MGMT-NET (ClinicalTrials.gov identifier:
NCT03217097
) was a phase II trial randomly assigning 1:1 for pMGMT or 2:1 for dMGMT-NETs to either ALKY or oxaliplatin (Ox). Inclusion criteria were a confirmed advanced pancreatic, thoracic, or unknown primary NETs with an indication for chemotherapy and tissue available. The primary aim was to detect a difference of 35% between the 3-month objective response rate (ORR) in pMGMT-NETs versus in dMGMT-NETs when treated with ALKY. A biomarker-stratified design was performed to compare ALKY and Ox in the dMGMT and pMGMT strata for the secondary end points. dMGMT was defined using pyrosequencing (PSQ; methylated
MGMT
≥9%) and using immunochemistry (
H
-score of MGMT <50) when PSQ was not interpretable.

RESULTS

From October 2018 to October 2021, 105 patients (55 pancreas, 38 thorax, 12 unknown) started either ALKY (n = 62) or Ox (n = 43). The median age was 63 years (range, 30-84), and 59% were males. NETs were G1 (19%), G2 (69%), or G3 (10%). Among patients with interpretable MGMT status, 56.9% (58 of 102) had a dMGMT-NET. The primary end point was not reached; the 3-month ORR was 10 (29.4%) versus 2 (8%), and the odds ratio was 3.5 (0.58-21.16),
P
= .172. However, best ORR (18 [52.9%]
v
3 [11.5%]) and median progression-free survival (14.6 [95% CI, 7.2 to 22.1]
v
11.3 [9.4 to 13.2] months) were higher for dMGMT-NETs versus pMGMT-NETs. MGMT status does not seem to affect the Ox efficacy.

CONCLUSION
Despite the fact that the primary end point was not reached, ALKY has clinical activity in patients with dMGMT-NETs.
Amiri Baraka's Humanist Theater: A Reading of A Black Mass
Authors: Fitzgerald Jason 
Published: November 2024

Abstract
This essay articulates Amiri Baraka's relationship to humanist universalism through his work as a theatermaker, in particular through his play A Black Mass. Baraka's Black nationalist writings are infused with humanist assumptions despite the apparent contradiction between humanist universalism and nationalist separatism. The essay nominates as poietic the form of humanism that Baraka values, meaning that, for Baraka, humans imagine new worlds into existence from materials taken by the world as it is. This poietic humanism values contingency, invention, and impermanence and refuses essentialisms. The essay begins by drawing from Baraka's essays on theater the claim that the work, or action, of revolutionary art is to set into motion a doubling, to produce oppositions that remain unsettled. Next is an extended reading of Baraka's play A Black Mass, first staged in New Jersey in 1966, which he uses to settle philosophical scores with the Nation of Islam. Although the play borrows its plot from the Nation of Islam's myth of Yakub, which casts the white race as fundamentally monstrous, A Black Mass resists a vision of history as racial destiny. It does so, first, by staging the production of the human as a category of exclusion and so critiquing the process of racialization, and second, by rooting its tragic plot structure in a break between the expressive self and the poietic community. The essay's conclusion briefly contextualizes Baraka's poietic humanism within late 1960s debates among nationalist and Negritude thinkers, suggesting Frantz Fanon as an important influence and reasserting a dynamic approach to racial difference in Baraka's vision of Black art.
Unfolding Memory in Adil Hasan's When Abba Was Ill
Authors: Bhattacharya Sreerupa 
Published: November 2024

Abstract
Adil Hasan's When Abba Was Ill stages the aesthetic and ethical tension involved in representations of illness and death. This article aims at parsing through the strategies employed in publishing what was meant to be a private record of the six months during which Hasan's family came to terms with the diagnosis of his father's cancer. On one hand, the article reflects on how the genre of the photobook affords the intimacy of encounter that such a project demands, and on the other, it demonstrates how Hasan's work oscillates between provoking and resisting the reader's identification with the photographs. While the photobook's title promises a retrospective account of the period, this article argues that the book emerges as eventually undercutting its own project. Even as it enacts the script of recollection, the photobook tends to obfuscate the memory of the time by blocking it, deferring its appearance, and ultimately rendering it opaque for readers.
Humanism in China (Zhongguo renben) and Recontextualizations of Chinese Documentary Photography
Authors: Spyra Bernd , Hilscher Sanja 
Published: November 2024

Abstract
Considered the first large-scale presentation of contemporary documentary photography by a Chinese institution, the traveling exhibition Humanism in China (Zhongguo renben) was documented through the publication of at least three separate photobooks, each addressing distinct domestic and international audiences in mainland China (2003), Germany (2006), and the United States (2009). These photobooks preserve curatorial choices made at the different stations of the exhibition regarding nature, number, and layout of photos in order to adapt to different audiences in China and abroad. Among these choices, the inclusion of historical, posed propaganda photos in the corpus of documentary photos, as well as the removal of eleven photos from the international editions of the photobook—allowing the transformation of the project from a critical appeal for reform into an element of official Chinese cultural diplomacy—makes different Chinese representational systems visible. Analytically, recognizing the signifiers of these systems opens new ways to investigate the photobooks, their distinct curatorial choices, and underlying conceptions of (inter)national representations of China.
The Rochester Model for Spinal CSF Leak Repair Simulation and Scoring
Authors: Jalal Muhammad I. , Santangelo Gabrielle , Samodal Joshua , Catanzaro Sandra , Furst Taylor , Singh Rohin , Li Herman , Jain Sameer , Singh Aman , Puvanesarajah Varun , Wensel Andrew , Paul David A. , Stone Jonathan J. 
Published: November 2024

BACKGROUND AND OBJECTIVE:
Iatrogenic spinal durotomies occur at a rate of 1% to 17%. Surgical simulation for durotomy repair is needed to provide affordable, accessible, and validated practice. This study sought to design and validate a simple 3-dimensional printed model for spinal cerebrospinal fluid (CSF) leak repair and to introduce the Rochester original objective structured assessment of technical skills (OSATS) CSF leak (ROCL) repair criteria for assessment.

METHODS:
A spinal model was designed to mimic a lumbar laminectomy with the L3-5 lamina removed and 3-dimensional printed using Vero polymers. The model was paired with a porcine collagen “dura” that was pressurized using IV saline and overlayed with gel-molded fascial, muscle, and skin layers with an opening. Participants were provided a training model with a 1.5-cm midline durotomy, surgical microinstrument set, microscope, and 6-0 prolene suture. The 25-point ROCL repair criteria were adapted from the original OSATS principles to assess proficiency in surgical repair by 2 blinded neurosurgeons not participating in the trials. Postsimulation survey data regarding model realism were collected.

RESULTS:
Six residents and 4 attendings participated. Median operative time in minutes was 13 minutes among residents and 7 minutes among attendings. Moreover, the ROCL score was a median of 19/25 for attendings and 15/25 for residents. The suture angle was statistically more consistent among senior residents and attendings compared with junior residents. Participants agreed that the model was realistic (median 4/5), useful for improving the operative technique (median 5/5), and would increase comfort in spinal CSF leak repair procedures (median 5/5). Each reusable model had a cost of $19.99 if printed with polylactic acid and each replacement dura cost <3¢.

CONCLUSION:
This study presents an affordable, realistic, and educational spinal CSF leak repair model and introduces ROCL for assessment.
Multicenter Randomized Controlled Clinical Trial to Compare the Safety and Performance of Two Bone Flap Fixation Systems
Authors: Gómez de la Riva Álvaro , Rico Marta , Voršič Matjaz , Rokavec Valentin , Asencio-Cortés Carlos , Muñoz-Hernández Fernando 
Published: November 2024

BACKGROUND AND OBJECTIVES:
Polymeric clamp-like devices present potential advantages regarding plates and screws to close craniotomies; however, no clinical research has provided enough evidence to compare them. This randomized controlled trial compares the clinical safety and performance of clamp-like devices with the standard of care for craniotomy closure: titanium plates and screws (P&S).

METHODS:
A prospective, double-arm, multicenter randomized controlled trial was performed at 3 sites, recruiting 60 patients undergoing neurosurgical interventions requiring craniotomy. Patients were randomly allocated to 2 groups depending on the bone flap fixation system to be used: plates and screws (any brand) and clamp-like devices (Cranial LOOP, NEOS Surgery S.L.). The primary end point of the study (bone flap alignment) was assessed 6 months after surgery through neuroimaging. Secondary end points included adverse events and device deficiency assessment, closure method usability assessed by the surgeon, and patient-reported device-related inconveniences.

RESULTS:
It was necessary to use a median of 3 Cranial LOOP and 4 plates and 8 screws to close craniotomies. All patients from both groups had equally good bone flap alignment. Most implantations were reported as easy or very easy for both groups, and surgeons were generally satisfied or very satisfied with both treatments. No related adverse events have been reported for any of the treatment groups. Two patients reported discomfort or protuberances caused by P&S; no inconveniences were reported for Cranial LOOP.

CONCLUSION:
Cranial LOOP performance is equal to P&S for fixation of the cranial bone flap. In addition, it presents some advantages, such as the use of a lower number of devices, potentially making this system more affordable, and the lack of discomfort previously linked with the use of P&S.
The Click-Based MNL Model: A Framework for Modeling Click Data in Assortment Optimization
Authors: Aouad Ali , Feldman Jacob , Segev Danny , Zhang Dennis J. 
Published: November 2024

We introduce the click-based MNL choice model, a framework for capturing customer purchasing decisions in e-commerce settings. Specifically, we augment the classical Multinomial Logit choice model by assuming that customers only consider the items they have clicked on before they proceed to compare their random utilities. In this context, we study the resulting assortment optimization problem, where the objective is to select a subset of products, made available for purchase, to maximize the expected revenue. Our main algorithmic contribution comes in the form of a polynomial-time approximation scheme (PTAS) for this problem, showing that the optimal expected revenue can be efficiently approached within any degree of accuracy. To establish this result, we develop several technical ideas, including enumeration schemes and stochastic inequalities, which may be of broader interest. Using data from Alibaba’s online marketplace, we fit click-based MNL and latent class MNL models to historical sales and click data in a setting where the online platform recommends a personalized six-product display to each user. We propose an estimation methodology for the click-based MNL model that leverages clickstream data and machine learning classification algorithms. Our numerical results suggest that clickstream data are valuable for predicting choices and that the click-based MNL model can outperform standard logit-based models in certain settings. This paper was accepted by Chung Piaw Teo, optimization. Funding: D. Segev was supported by the Israel Science Foundation [Grant 1407/20]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2021.00281 .
TERCIARIZACIÓN INDUSTRIAL A PARTIR DE LA ADOPCIÓN DE LA ECONOMÍA DEL CONOCIMIENTO EN ARGENTINA
Authors: Buffalo Luciana 
Published: November 2024

Este trabajo busca comprender cómo avanza el sector terciario avanzado (conocimientos tecnológicos digitales, I+D) en la estructura productiva Argentina, sobre todo de la industria, como parte de la profunda reestructuración productiva global del sistema capitalista.
La terciarización económica, como proceso global responde a un cambio estructural, y la tendencia es hacia una especialización productiva que demanda ahora mayor complejidad tecnológica tanto en términos materiales como inmateriales (infraestructura urbana de comunicaciones como fibra óptica, internet de alta velocidad, comunicación satelital, 5G, equipamiento informático de alto rendimiento, plataformas y sistemas digitales, selectividad de la calificación de mano de obra, I+D, entre otros).
Diversos estudios dan cuenta de una integración creciente entre industria y servicios, con industrias cada vez más terciarizadas, que demandan servicios especializados dentro y fuera de su ámbito de producción.
Analizar este fenómeno es relevante, en tanto el sector terciario es explicativo de una gran cantidad de actividades, y corresponde a una forma particular de división del trabajo internacional e interna en cada país. Al mismo tiempo, la expansión del sector terciario avanzado hacia adentro de las industrias, trae consigo una reorganización de las estructuras productivas, sociales y territoriales, evidenciando profundas transformaciones no solo en el sector industrial, sino también en las regiones donde este sector es relevante.
URBANIZACIÓN CONTEMPORÁNEA EN SUR DE BRASIL
Authors: Soares Paulo Roberto Rodrigues 
Published: November 2024

El artículo discute la urbanización contemporánea y sus rebatimientos empíricos en una ciudad media de Sur de Brasil, la ciudad de Pelotas, estado de Rio Grande do Sul. Partimos de las conclusiones de una tesis doctoral realizada en 2002. Se trabajará los cambios en la producción espacial de la ciudad en los últimos veinte años y si las tendencias verificadas en la tesis se han confirmado. En las conclusiones de la tesis ya se demarcaban tendencias de dispersión urbana, descentralización de servicios y de fragmentación socioespacial. Dichas tendencias se han exacerbado en las décadas iniciales del siglo XXI. Nuestro análisis partirá de autores y autoras de la urbanización contemporánea para analizar los distintos movimientos de la producción espacial en la ciudad y sus nexos con procesos globales. Lo observado en los últimos veinte años ha sido la complexificación del espacio urbano con la llegada de nuevos agentes, nuevos procesos y la producción de un espacio urbano más fragmentado y polarizado. Se destacan las urbanizaciones cerradas, además de una nueva ideología urbana, con experimentos del “nuevo urbanismo”, sin embargo, destinados a grupos sociales muy específicos. Finalmente hay que enfatizar el espacio “post-pandémico”, en la cual la decadencia del centro histórico es evidente.
Terceiro-mundismo e construção de redes cinematográficas: de Hacia un Tercer Cine aos encontros de Argel (1969-1973)
Authors: Araújo Lima Ivan 
Published: November 2024

Neste artigo, apresento um pouco do contexto que levou a produção do manifesto Hacia un Tercer Cine, bem como analiso a maneira pela qual os debates gerados a partir do mesmo contribuíram para a construção de um imagnário tricontinentalista ao longo da Guerra Fria. A construção desta rede se relaciona com o surgimento do Movimento dos Países Não-Alinhados, cujas posturas defendidas alimentam, junto com manifestos como Hacia un Tercer Cine, expressões do mencionado terceiro-mundismo cinematográfico, entre as quais a realização do Encontro de Cineastas de Argel, em 1973, ocorrido quase em paralelo com IV Conferência do Movimento Não-Alinhado, que foi sediado na mesma cidade. Tendo como base os conceitos de Terceiro Cinema e cultura nacional, o movimento reivindicou a descolonização cultural em suas nações.
EMPOWERMENT DE PROFESSORES E ALUNOS POR MEIO DA PEDAGOGIA DO ESPORTE
Authors: Correia Mesaque Silva 
Published: November 2024

O referido estudo ensaístico tem como objetivo suscitar junto aos profissionais da área da Educação Física Escolar algumas reflexões inerentes à possibilidade de existir um processo de empowerment de professores e alunos por meio da pedagogia do esporte. Uma vez que a prática do esporte, por sua função incontestável no seio da escola, necessita superar o processo esportivo reprodutor e apoiar-se em uma concepção que insira o movimento humano no mundo vivido do educando e o problematize de forma contextualizada para se tornar significativo e, por extensão, uma via de acesso à conscientização social, política e corporal dos alunos. Para tanto, busca apoiar-se em um arcabouço teórico que de forma que possibilita pensar o ensino dos esportes para além das linhas da quadra e das regras do jogo, mas como um conteúdo que pode auxiliar no desenvolvimento social, moral e cognitivo dos alunos.
O Fomento às Startups e Cidades Inteligentes no Âmbito das Políticas Públicas de Inovação
Authors: Santos Maria Salomé Albuquerque , Amaral Cláudia Tannus Gurgel do 
Published: November 2024

O presente artigo tem por objetivo analisar o fomento às Startups a partir da contextualização da Lei Complementar nº 182/2021, o Marco Legal das Startups (MLS). E consiste em uma pesquisa exploratória e bibliográfica dos aspectos legais do Marco Legal; das características dos Contratos de Soluções Inovadoras pelo Estado e sua relação com a Lei nº 14.133/21; do MLS no contexto do Plano de Transformação Digital (Decreto nº 10.332/20); do fomento às Startups como possível ferramenta para a implementação do conceito de Cidades Inteligentes no Brasil; e a judicialização, no âmbito dos Tribunais Superiores e Estaduais, tomando por base os termos “Smart City”, “Smart Cities”, “Cidades Inteligentes”, “marco legal das Startups” e “LC nº 182”. Como resultado, verificou-se que o MLS atribuiu à inovação tecnológica como uma característica de atuação das Startups; que a Carta Brasileira para Cidades Inteligentes aponta, dentre os objetivos traçados, as Startups como aliado da gestão municipal. E na pesquisa jurisprudencial, verificou-se nos resultados encontrados, que o mérito dos litígios, tiveram como cerne a ofensa à competência privativa da União (art. 22, XXVII, da CF/88); às normas da Constituição Estadual de Minas Gerais e às regras do processo licitatório.