bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Coevolution of Massive Quiescent Galaxies and Their Dark Matter Halos over the Last 6 Billion Years
Authors: Zahid H. Jabran , Geller Margaret J. , Damjanov Ivana , Sohn Jubee 
Published: June 2019

Abstract
We investigate the growth of massive quiescent galaxies at z < 0.6 based on the Sloan Digital Sky Survey and the Smithsonian Hectospec Lensing Survey, two magnitude-limited spectroscopic surveys of high data quality and completeness. Our three-parameter model links quiescent galaxies across cosmic time by self-consistently evolving stellar mass, stellar population age-sensitive D

n
4000 index, half-light radius, and stellar velocity dispersion. Stellar velocity dispersion is a robust proxy of dark matter halo mass; we use it to connect galaxies and dark matter halos and thus empirically constrain their coevolution. The typical rate of stellar mass growth is

, and dark matter growth rates from our empirical model are remarkably consistent with N-body simulations. Massive quiescent galaxies grow by minor mergers with dark matter halos of mass

and evolve parallel to the stellar mass–halo mass (SMHM) relation based on N-body simulations. Thus, the SMHM relation of massive galaxies apparently results primarily from dry minor merging.
Adaptation socio-affective des enfants âgés de 9 à 12 ans et utilisation d’Internet au domicile
Authors: Berdot-Talmier Laurence , Zaouche-Gaudron Chantal 
Published: June 2019

La plupart des enfants français ont, maintenant, accès aux technologies numériques de l’information et de la communication (TNIC) à leur domicile. En s’appuyant sur le modèle écosystémique de Bronfenbrenner (1979, 1986), les auteurs de cette recherche visent à saisir l’influence des environnements – utilisation d’Internet au domicile (sous-système technologique ; Johnson, 2010a) et caractéristiques socio-économiques (environnement microsystémique) – sur le développement socio-affectif des enfants (ontosystème), en fonction du sexe. Des questionnaires ont été administrés à 498 enfants (244 garçons et 254 filles) âgés de 9 à 12 ans et à leurs parents. Les indices d’utilisation d’Internet au domicile expliquent une part un peu plus importante des variations des scores de l’adaptation socio-affective des enfants que ceux relatifs aux caractéristiques socio-économiques des parents.
Henri Piéron (1881-1964) disciple d’Édouard Toulouse (1865-1947)
Authors: Huteau Michel 
Published: June 2019

Henri Piéron commence sa carrière scientifique au laboratoire d’Édouard Toulouse en 1900. Il devient vite son principal collaborateur. Piéron quittera ce laboratoire en 1912, mais il restera proche de Toulouse. Ils ont les mêmes conceptions épistémologiques – ce sont des positivistes scientistes – et politiques – ce sont des républicains qui placent l’égalité au premier plan de leurs valeurs. L’examen des lettres de Toulouse adressées à Piéron témoigne de leur proximité. Piéron a joué un rôle actif dans le développement de l’orientation professionnelle en France. Son projet est identique à celui de Toulouse : l’orientation professionnelle doit être fondée sur le diagnostic d’aptitudes héréditaires. Les pratiques qui se sont mises en place par la suite en sont éloignées.
Le linceul, accompagner et envelopper une dernière fois les disparus
Authors: van den Eerenbeemt-Penant Sharon 
Published: June 2019

L’auteure partage ses expériences d’accompagnatrice dans le cadre d’un atelier créatif d’accompagnement de deuil, ou elle a choisi de proposer de faire un linceul, une enveloppe symbolique sous la forme du dernier habit pour accompagner le défunt. Dans sa plus simple expression, on pourrait dire que la création voire la créativité est l’aptitude à concevoir et à vivre une réalité autrement. L’homme s’exprime depuis la nuit des temps par ses mains. Faire son deuil, créer une trace, faire un objet symbolique de ses mains, dans un temps ritualisé en soi, toutes ces actions sont remarquablement présentes dans toutes les civilisations. Puisque nous sommes au moment de « faire », en lien avec notre histoire singulière avec le défunt, le linceul permet d’habiller, accompagner, protéger le disparu. Il permet aussi de vivre ce moment de lien symbolique, seul ou en le partageant avec le groupe familial, amical. Il permet aussi de s’approprier le moment des obsèques plus intimement, le cercueil n’est plus seulement un cercueil. Le cercueil permet de porter le linceul créé par les siens pour vêtir le défunt une dernière fois.
Typologie lexicale comparée des langues romanes : les spécificités de la langue française et leur implication sur la cognition et la culture
Authors: Begioni Louis , Rocchetti Alvaro 
Published: June 2019

L’article étudie la manière dont les mots se construisent en français : ils deviennent de plus en plus compacts et aboutissent fréquemment à des monosyllabes. Le mot écrit se comporte comme un idéogramme et son correspondant oral tend à devenir un idéophone morphologiquement inanalysable. Le verbe perd progressivement la désinence personnelle, ce qui tend à rendre plus abstrait le lien entre son signifiant et son signifié. Le rapport existant dans les langues endocentriques entre le verbe et le nom s’est reporté en français, devenu typologiquement exocentrique, sur l’opposition entre un lexique construit allégé et une syntaxe plus développée et soumise à des règles de fonctionnement logique plus strictes.
Of Gods and Kings: Ashur Imagery in Nahum
Authors: Cook Gregory D. 
Published: June 2019

Abstract
Despite recognizing allusions to Ishtar in Nahum, commentators have not discussed the presence of Ashur imagery in the book. This article contends that Nah 3:18 identifies Yhwh’s ambiguous single male adversary as Assyria’s war god, Ashur. The phrase (3:18) is multivalent, referring to both the “king of Assyria” and “King Ashur.” When the verse is read in light of Assyrian inscriptions, it taunts Ashur that the human kings of Assyria no longer perform the duties assigned to them: shepherding and gathering the god’s people. The prophet, therefore, prophesied more than just Assyria’s demise; he also vilified the religion behind it.
De informatieplicht voor de franchisegever naar Nederlands recht
Authors: Kruisinga S.A. , Nijenhof-Wolters M.I. 
Published: June 2019

De informatieplicht voor de franchisegever naar Nederlands recht. Beschouwingen naar aanleiding van het Albert Heijn-arrest
In het Albert Heijn-arrest heeft de Hoge Raad opnieuw bevestigd dat naar huidig Nederlands recht geen algemene regel geldt dat een franchisegever een (toekomstige) franchisenemer moet inlichten omtrent de te verwachten omzet of omtrent de winstverwachting. De bijzondere omstandigheden van het geval kunnen echter wel een zodanige verplichting meebrengen. De vraag rijst of in het voorontwerp van de Wet Franchise dat op 12 december 2018 werd gepubliceerd een andere benadering is gekozen. In dit voorontwerp wordt voorgesteld een – vrij ruim geformuleerde – informatieplicht voor de franchisegever te introduceren. In deze bijdrage wordt ingegaan op het Albert Heijn–arrest en wordt de uitkomst van deze procedure afgezet tegen het Nederlandse conceptwetsvoorstel en de Belgische regelgeving voor franchiseovereenkomsten.
Linear Data-Model Based Adaptive ILC for Freeway Ramp Metering without Identical Conditions on Initial States and Reference Trajectory
Authors: Liang Hao , Lin Na , Chi Ronghu , Sun Yumei 
Published: June 2019

Although freeway traffic system is conducted with a repeatable pattern day-to-day, the initial volume/or speed and the desired density of the traffic flow may vary with days due to the external disturbances. In this paper, a new linear data-model based adaptive ILC (LDM-AILC) is proposed to address ramp metering in a macroscopic level freeway environment. A linear data-model is developed for the nonlinear macroscopic traffic flow model by introducing an equivalent dynamical linearization approach in the time domain. Then the LDM-AILC is designed with a feedback control law and a parameter updating law. The proposed scheme is data-driven intrinsically, where only the I/O data is required for the controller design and analysis. The convergence is shown by rigorous analysis without any identical conditions exposed on both the initial state and the reference trajectory. Extensive simulation results are provided to verify the effectiveness of the proposed LDM-AILC.
Biochemistry and Molecular Biology of Mechanisms of Action of Fibrates – An Overview
Authors: Prasad A.S. V. 
Published: June 2019

Fibrates are a class of medication that mainly lowers the blood triglyceride levels. They reduce the LDL and increase the levels of HDL C, in the blood. Clofibrate, the first member to be discovered in 1962 , and introduced in USA in 1967, is withdrawn in 2002, due to unexplained hepatomegaly, hepato-toxicity and possible risk of hepatic cancer. Other fibrates are introduced in the late 1970s and early 1980s, such as gemfibrozil in the United States and bezafibrate and ciprofibrate in Europe. Their lipid lowering effects are found to decrease CVS risk , progression of atherosclerosis and metabolic syndrome, macrovascular and microvascular diabetic complications like stroke, myocardial infarction, peripheral vascular disease and diabetic retinopathy .Various clinical trials like VA-HIT trial (Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial) , FIELD trail. (the Fenofibrate Intervention and Event Lowering in Diabetes) Helsinki Heart Study, ACCORD -Lipid trial (The lipid component of the Action to Control Cardiovascular Risk in Diabetes trial ) and BIP (Bezafibrate Infarction Prevention Study) trial and angiography trials, like LOCAT (Lopid Coronary Angiography Trial) and BECLAIT (Bezafibrate Coronary Atherosclerosis Intervention Trial) demonstrated the beneficial effects of gemfibrozil and fenofibrate. Their mechanism of action remained obscure for three decades, ie till 1990s, when their mode of action was found. The Mechanism of action of fibrates include limitation of substrate availability for triglyceride synthesis in the liver, promotion of the action of lipoprotein lipase, (LPL) modulation of low density lipoprotein receptor/ligand interaction and stimulation of reverse cholesterol transport The biochemical and molecular mechanisms involving the various enzymes like LCAT (Lecithin-cholesterol acyl transferase) and CYP7A1 etc. (cholesterol 7-alpha-monooxygenase or cytochrome P450 7A1 (CYP7A1) ) , transporters like ABC , CETP (ATP-binding cassette transporter, Cholesterol ester binding protein) and NTCP, OATP (Na+-dependent taurocholate transporter / organic anion transporters) . These are the.) and nuclear factors like LXR, PPAR alfa etc. (liver orphan receptor α , and peroxisome proliferative nuclear factor) , in relation to the mechanisms of action of fibrates are discussed . Areas of current interests in literature are briefed.
Antibiotic Susceptibility Profile of Bacteria Isolated from Kenyan Bank Notes Circulating in Nyeri Town
Authors: Muguongo S. G. , Nyamache A. K. , Maingi J. M. 
Published: June 2019

Aims: The aim of this study was to characterize bacteria isolated from circulating Kenyan banknotes and also antibiotic susceptibility profiles within Nyeri County.
Study Design: This was a cross-sectional study and simple random sampling was used to collect 25 of each paper currency denomination.
Place and Duration of Study: Samples analyses were done at Outspan Teaching and Referral Hospital (OTRH) laboratory, between March, 2019 and April, 2019.
Methodology: Total of 125 currencies of five different denominations were collected from different marketing sources such as Butcheries, Restaurants, Health facilities, Mpesa outlets and Transport Saccos and dropped in sterile bags. The bacterial isolates were characterized on the basis of their morphology, staining and biochemical tests. Antibiotic sensitivity tests were done by Kirby Bauer disc diffusion technique.
Results: Total of 19 different bacterial species were isolated from five Kenyan Bank note currencies. Of these, 37 (52.2%) was Staphylococcus aureus followed by Staphylococcus sciuri ssp.lentus 7 (9.9%), Staphylococcus gallinarum 2 (2.8%), Staphylococcus intermedius 6 (8.5%), Micrococcus sp. 1 (1.4%), Staphylococcus schleiferi ssp.coagulans 2 (2.8%), Staphylococcus sciuri ssp.rodentium 1 (1.4%), Kluyvera ascorbata 1 (1.4%), Proteus penneri 1 (1.4%), Aeromonas media 3 (4.2%), Burkholderia cepacia ssp.komplex (1.4%), Aeromonas enteropelogenes 1 (1.4%), Enterobacter cloacae 1 (1.4%), Klebsiella oxytoca 2 (2.8%), Leclercia adecarboxylata 1 (1.4%), Raoultella ornithinolytica 1 (1.4%), Vibrio metschnikovii 1 (1.4%), Myroides odoratus 1 (1.4%) and Yersinia pestis 1 (1.4%). Overall gram positive and gram negative bacterial isolates exhibited resistance to vancomycin, clindamycin and amoxycilin with percentages 40 (71%), 28 (50%), and 37 (66%) and 9 (64%), 8 (57%) and 6 (43%) respectively.
Conclusion: This study revealed that Kenyan banknote currencies circulating in Nyeri County were contaminated with different pathogenic and potential pathogenic bacteria including multi drug resistant strains. Hence, great care must be taken while handling money during the preparation and handling of food to avoid cross contamination.
New insights into structural and functional relationships between LonA proteases and ClpB chaperones
Authors: Rotanova Tatyana V. , Andrianova Anna G. , Kudzhaev Arsen M. , Li Mi , Botos Istvan , Wlodawer Alexander , Gustchina Alla 
Published: June 2019

LonA proteases and ClpB chaperones are key components of the protein quality control system in bacterial cells. LonA proteases form a unique family of ATPases associated with diverse cellular activities (AAA+) proteins due to the presence of an unusual N‐terminal region comprised of two domains: a β‐structured N domain and an α‐helical domain, including the coiled‐coil fragment, which is referred to as HI(CC). The arrangement of helices in the HI(CC) domain is reminiscent of the structure of the H1 domain of the first AAA+ module of ClpB chaperones. It has been hypothesized that LonA proteases with a single AAA+ module may also contain a part of another AAA+ module, the full version of which is present in ClpB. Here, we established and tested the structural basis of this hypothesis using the known crystal structures of various fragments of LonA proteases and ClpB chaperones, as well as the newly determined structure of the Escherichia coli LonA fragment (235–584). The similarities and differences in the corresponding domains of LonA proteases and ClpB chaperones were examined in structural terms. The results of our analysis, complemented by the finding of a singular match in the location of the most conserved axial pore‐1 loop between the LonA NB domain and the NB2 domain of ClpB, support our hypothesis that there is a structural and functional relationship between two coiled–coil fragments and implies a similar mechanism of engagement of the pore‐1 loops in the AAA+ modules of LonAs and ClpBs.
Development and Reproducibility of a First Metatarsophalangeal Joint Osteoarthritis Magnetic Resonance Imaging Scoring System
Authors: Munteanu Shannon E. , Auhl Maria , Tan Jade M. , Landorf Karl B. , Elzarka Ayman , Tan Beng , Menz Hylton B. 
Published: June 2019

ObjectiveTo develop a magnetic resonance imaging (MRI) atlas for the assessment of osteoarthritis (OA) of the first metatarsophalangeal (MTP) joint, and to assess its intra‐ and interexaminer reproducibility.MethodsMRI (proton density with and without fat suppression) was performed on the first MTP joint of 60 participants (30 participants with first MTP joint OA and 30 participants without first MTP joint OA). Characteristic MRI features of OA were then used to develop an MRI atlas of first MTP joint OA. The atlas assessed osteophytes (dorsal metatarsal head, plantar metatarsal head, dorsal proximal phalanx), bone marrow lesions (metatarsal head, proximal phalanx, sesamoids), cysts (metatarsal head, proximal phalanx), effusion‐synovitis (dorsal, plantar), joint space narrowing (metatarsal‐proximal phalanx, metatarsal sesamoids), and cartilage loss. To assess the reproducibility of the atlas, 2 examiners independently rated the MRIs of 30 participants on 2 occasions. Intra‐ and interexaminer reproducibility were determined using percentage agreement and Gwet's AC1.ResultsObservations using the atlas demonstrated fair‐to‐perfect intraexaminer reproducibility (percentage agreement from 67% to 100%, and Gwet's AC1 from 0.38 to 1.00) and fair‐to‐almost‐perfect interexaminer reproducibility (percentage agreement from 67% to 98%, and Gwet's AC1 from 0.40 to 0.96).ConclusionAn MRI scoring system for the assessment of OA of the first MTP joint has been developed. The atlas demonstrates excellent intra‐ and interexaminer reproducibility. The atlas has the potential to allow for a better understanding of the cause(s) of pain in first MTP joint OA.
Enhanced adaptive control for a benchmark piezoelectric‐actuated system via fuzzy approximation
Authors: Yousef Hassan A , Hamdy Mohamed , Saleem Ashraf , Nashed Kyrillos , Mesbah Mustafa , Shafiq Muhammad 
Published: June 2019

SummaryThis paper investigates the problem of the high precision tracking control of piezoelectric actuators (PEAs) without using the inverse of the uncertain hysteresis. Based on fuzzy system approximator and particle swarm optimization (PSO) algorithm, a proposed enhanced
adaptive controller is developed. The proposed controller provides fast and robust adaptation simultaneously with guaranteed desired transient performance. Moreover, it has a simple form and requires fewer adaptation parameters. The adaptation gain is determined via PSO algorithm. The proposed controller is tested on a lab‐scale PEA system. Experimental results with comparative studies with different techniques have been developed. The simulation results reveal that the proposed controller outperforms the other controllers in terms of normalized root‐mean‐square and maximum tracking errors for different frequencies.
Pyridyl Disulfide Functionalized Polymers as Nanotherapeutic Platforms
Authors: Sui Binglin , Cheng Chen , Xu Peisheng 
Published: June 2019

AbstractWith the development of modern polymer synthesis techniques, polymer therapeutics have emerged and rapidly grown into a research hotspot and a promising tool for biomedical applications owing to their outstanding advantages in comparison to conventional drug therapy. Among an enormous number of polymers developed for therapeutic purposes, pyridyl disulfide (PD) group functionalized polymers have attracted increasing attention over the past decades. The highly reactive PD group could be replaced by almost any thiol‐containing groups, leading to the production of a disulfide bond. More importantly, the redox‐sensitive disulfide bond generated from the replacement can be exploited to develop stimuli‐responsive polymer therapeutics which will protect the loaded cargoes from premature leakage, while programmably releasing them in response to endogenous redox stimuli such as glutathione. Herein, the development of PD‐incorporated polymers and summarized PD‐based monomers that have been synthesized to prepare various functional polymeric architectures are reviewed. Moreover, this review also discusses the difference between polymers with PD as repeating pendants or terminal groups and emphasizes on the diverse promising applications of these polymers as nanotherapeutic platforms in the biomedical field.
A Generalized Crystallization Protocol for Scalable Deposition of High‐Quality Perovskite Thin Films for Photovoltaic Applications
Authors: Guo Fei , Qiu Shudi , Hu Jinlong , Wang Huahua , Cai Boyuan , Li Jianjun , Yuan Xiaocong , Liu Xianhu , Forberich Karen , Brabec Christoph J. , Mai Yaohua 
Published: June 2019

AbstractMetal halide perovskite solar cells (PSCs) have raised considerable scientific interest due to their high cost‐efficiency potential for photovoltaic solar energy conversion. As PSCs already are meeting the efficiency requirements for renewable power generation, more attention is given to further technological barriers as environmental stability and reliability. However, the most major obstacle limiting commercialization of PSCs is the lack of a reliable and scalable process for thin film production. Here, a generic crystallization strategy that allows the controlled growth of highly qualitative perovskite films via a one‐step blade coating is reported. Through rational ink formulation in combination with a facile vacuum‐assisted precrystallization strategy, it is possible to produce dense and uniform perovskite films with high crystallinity on large areas. The universal application of the method is demonstrated at the hand of three typical perovskite compositions with different band gaps. P‐i‐n perovskite solar cells show fill factors up to 80%, underpinning the statement of the importance of controlling crystallization dynamics. The methodology provides important progress toward the realization of cost‐effective large‐area perovskite solar cells for practical applications.
Dihydrosulfenylation of Alkynes with Thiols Using a Nickel Catalyst through a Radical Process
Authors: Taniguchi Nobukazu , Kitayama Kenji 
Published: June 2019

AbstractThe dihydrosulfenylation of alkynes by thiols was achieved in the presence of a nickel catalyst under aerobic conditions. The reaction proceeded by employing a radical process, and anti‐Markovnikov type dithioacetals were regioselectively synthesized. The nickel catalyst efficiently promoted the procedure using alkyl alkynes or alkyl thiols.
Ultrasensitive Detection of Salmonella and Listeria monocytogenes by Small‐Molecule Chemiluminescence Probes
Authors: Roth‐Konforti Michal , Green Ori , Hupfeld Mario , Fieseler Lars , Heinrich Nadine , Ihssen Julian , Vorberg Raffael , Wick Lukas , Spitz Urs , Shabat Doron 
Published: June 2019

AbstractDetection of Salmonella and L. monocytogenes in food samples by current diagnostic methods requires relatively long time to results (2–6 days). Furthermore, the ability to perform environmental monitoring at the factory site for these pathogens is limited due to the need for laboratory facilities. Herein, we report new chemiluminescence probes for the ultrasensitive direct detection of viable pathogenic bacteria. The probes are composed of a bright phenoxy‐dioxetane luminophore masked by triggering group, which is activated by a specific bacterial enzyme, and could detect their corresponding bacteria with an LOD value of about 600‐fold lower than that of fluorescent probes. Moreover, we were able to detect a minimum of 10 Salmonella cells within 6 h incubation. The assay allows for bacterial enrichment and detection in one test tube without further sample preparation. We anticipate that this design strategy will be used to prepare analogous chemiluminescence probes for other enzymes relevant to specific bacteria detection and point‐of‐care diagnostics.
Guiding Drugs to Target‐Harboring Organelles: Stretching Drug‐Delivery to a Higher Level of Resolution
Authors: Louzoun‐Zada Sivan , Jaber Qais Z. , Fridman Micha 
Published: June 2019

AbstractThe ratio between the dose of drug required for optimal efficacy and the dose that causes toxicity is referred to as the therapeutic window. This ratio can be increased by directing the drug to the diseased tissue or pathogenic cell. For drugs targeting fungi and malignant cells, the therapeutic window can be further improved by increasing the resolution of drug delivery to the specific organelle that harbors the drug's target. Organelle targeting is challenging and is, therefore, an under‐exploited strategy. Here we provide an overview of recent advances in control of the subcellular distribution of small molecules with the focus on chemical modifications. Highlighted are recent examples of active and passive organelle‐specific targeting by incorporation of organelle‐directing molecular determinants or by chemical modifications of the pharmacophore. The outstanding potential that lies in the development of organelle‐specific drugs is becoming increasingly apparent.