bluuebunny/crossref_metadata_2025_split huggingface dataset:
Policy implications for the improvement of technology transfer and commercialization process in the Indian context
Authors: Sheth Bhavisha P. , Acharya Satya Ranjan , Sareen S.B. 
Published: May 2018

PurposeScientific innovation has resulted in the development of newer technologies for the betterment of humankind. Academic and research organizations are the places where these technologies are actually ideated and/or invented. However, the process of technology transfer and its eventual successful commercialization covers many other facets, in addition to the scientific research alone. This study aims to draw attention towards certain policy gaps and thereby suggest plausible solutions for the improvement of technology transfer process in the Indian context.Design/methodology/approachHere, the authors present an extensive Web survey of technologies available for transfer/commercialization in 12 major Indian research organizations, namely, Indian Council of Agricultural Research (ICAR), Indian Council of Medical Research, Council of Scientific and Industrial Research, Defence Research and Development Organisation, Department of Atomic Energy, Department of Biotechnology, Indian Space Research Organisation, Indian Institute of Technology (IIT) Bombay, Indian Institute of Science Bangalore, IIT Delhi, IIT Kharagpur and IIT Kanpur.FindingsA total of 2,921 technologies were found to be available with respect to the above-mentioned organizations, with the highest of these in agricultural sciences and the maximum reported by ICAR.Research limitations/implicationsCertain significant policy interventions of this study include the need of a central framework for deposition, management and dissemination of institutionally developed technologies. More attention and support is required for the technologically less developed research areas, and there is a need for the promotion of funding mechanisms for the prototype development, in addition to the already available funding schemes for other stages of technology commercialization.Practical implicationsHence, the successful commercialization of the innovation from the Indian research labs requires the restructuring of the existing policies to eventually facilitate the economic growth of the nation.Originality/valueThis study discusses the major policy gaps of the Indian technology transfer process. For this, an extensive Web survey was carried out to enlist the various technologies available for transfer and commercialization in India from 12 major research organizations. The study presents the results and some major policy implications of the technology transfer and commercialization process in the Indian context.
Examining systematic technological learning of Syrian textile industry
Authors: Ghazinoory Sepehr , Ali Ali Ammar , Hassanzadeh AliReza , Majidpour Mehdi 
Published: May 2018

PurposeBecause of importance of technological learning for less developed countries, the notion has received increasing attention of scholars. The purpose of this paper is to investigate technological learning systematically by assessing the effect of technology transfer actors on technological learning in less developed countries context.Design/methodology/approachThe paper presents assessment model by adopting technological learning concept based on technology absorption and incremental innovation at firm level and identifying key roles of technology transfer actors (State – Scientific and technological infrastructure – Industry) that affect technological learning. The paper follows survey as research methodology. Thus, a questionnaire was addressed to 33 Syrian textile factories to examine the assessment model. Simple linear, multiple linear and ordinal regression analyses are preformed to examine relationships of model components.FindingsThe regression models show notable ability of technology transfer actors to explain technological behavior of firms to accumulate operative capability and consequently to generate passive incremental innovation. The findings indicate passive technical change system of Syrian textile industry. Therefore, goal-oriented evaluation of actual technology policy is preliminary step for achieving improvements, as well as activating scientific and technological infrastructure role by enabling strong relationships with industry and supporting interactions of domestic firms of textile industry and with foreign players.Originality/valueThe paper enriches technological learning literature by proposing systematic approach that sets the nature of technical change process of less developed countries in core of analysis. Moreover, it provides a guide for technological learning practices at firm level and for policymakers based on assessing actual status of Syrian textile industry.
Investing in strategic development
Authors: Aaltola Pasi 
Published: May 2018

PurposeThis paper aims to explore management control in the strategic development of business model and managerial innovations. The issue is approached from the perspective of managerial work, aiming to outline what managers consider as essential elements of management control in these often iterative and learning-intensive developmental activities.Design/methodology/approachThe study is based on the views of 20 managers engaged in strategic development and its control in various organisations. The interview data consist of the respondents’ experiences and project cases involving non-technological innovations. Qualitative content analysis is used to identify three key concepts of management control of business model and managerial innovations.FindingsThe findings suggest that with managerial and business model innovation, appropriate management control could be established by aligning the innovation being developed with the strategic story of the organisation, leveraging co-creational projects and experimentation with close customer contact.Research limitations/implicationsThe focus of this qualitative research is on building an initial framework. Future research could expand understanding of managerial work and accounting by examining this study’s outcomes in more practical detail in various contexts.Practical implicationsThe findings of this study lead managers and researchers to consider management control of non-technological innovations as an enabling system supporting successful innovations.Originality/valueThis study adds a unique perspective to the literature by conceptualising and offering managerial implications for management control in the context of strategic development of non-technological innovations.
Regulatory intensity in English and German professional football
Authors: Bachmaier Birgit , Lammert Joachim , Plumley Daniel , Wilson Robert , Hovemann Gregor 
Published: May 2018

PurposeIn order to secure a proper execution of sporting competitions, national governing bodies of professional football leagues apply specific regulatory procedures. In this context, special focus is placed on requirements that are supposed to ensure financial stability of clubs. They, in turn, help avoid negative economic externalities, i.e. the problem that financial difficulties from one club can affect other clubs and stakeholders due to the interdependent relationships of the competition. These regulations on a national level in European professional football leagues show several significant differences. Therefore, the purpose of this paper is to comprehensively analyze financial regulatory procedures of professional football leagues to generate possible improvements of the regulations in detail.Design/methodology/approachUsing a document analysis of the regulation books of the English Premier League and German Bundesliga (BL), this study compares the regulatory procedures of those important European professional football leagues. Further evaluation was performed through a qualitative content analysis to develop a category system including six categories with 72 criteria from deductive and inductive procedures. For more advanced coding, an assessment scale was integrated.FindingsCompared to the Premier League, the regulation of the BL points to a more intensive regulation in all categories and across all analyzed indices. The results of both leagues partially reveal that assessment and monitoring requirements tend to be ineffective, which can substantially endanger the achievement of the whole monitoring process’ aims. The intention to ensure the financial stability for securing the league competition can be missed in such a situation and negative economic externalities cannot be prevented effectively.Originality/valueFor the first time, this study includes all relevant requirements of financial club assessment and monitoring. Thereby, an abstract comprehensive and systematic structure for professional team sports leagues is described and allows for a concrete international comparison of two European professional football leagues. At the end, several approaches to improve the regulatory framework are provided.
Mobile technologies and applications towards smart tourism – state of the art
Authors: Dorcic Jelena , Komsic Jelena , Markovic Suzana 
Published: May 2018

PurposeThe popularity of mobile technologies and applications is constantly growing and undoubtedly changing consumers’ and providers’ behavior. The purpose of this study is to provide a comprehensive systematic literature review of academic research related to mobile technologies and applications in smart tourism published between 2012 and June 2017.Design/methodology/approachPublished peer-reviewed articles were gathered from the three largest and most popular online databases and search engines – EBSCO host, Science Direct and Google Scholar and ENTER conference proceedings. Based on a keyword-driven search and content analysis, 126 articles were determined to be relevant to this study.FindingsSelected publications were analyzed in accordance with the proposed research questions and thematically classified into three main categories: consumer perspective, technological perspective and provider perspective. The findings contribute to a better overall understanding of recent research into mobile technologies and applications in smart tourism by presenting the main results, methods, trends and other insights of relevant publications.Research limitations/implicationsAlthough the researchers used two databases, one search engine and ENTER conference proceedings to collect articles, there is the possibility that some studies connected to the topic were not included. The study did not include books, other conference proceedings, literature reviews, theses, business reports and other possibly relevant publications.Originality/valueThis study provides a systematic review of the most recent published academic research (2012-June 2017; also including “Online First” articles) on mobile technologies and applications in smart tourism. The results of this study provide an agenda for future research in tourism and hospitality industry by identifying major trends and developments in smart tourism.
Coastal wetland adaptation to sea level rise: Quantifying potential for landward migration and coastal squeeze
Authors: Borchert Sinéad M. , Osland Michael J. , Enwright Nicholas M. , Griffith Kereen T. 
Published: May 2018

Abstract

Coastal wetland ecosystems are expected to migrate landwards in response to rising seas. However, due to differences in topography and coastal urbanization, estuaries vary in their ability to accommodate migration. Low‐lying urban areas can constrain migration and lead to wetland loss (i.e. coastal squeeze), especially where existing wetlands cannot keep pace with rising seas via vertical adjustments. In many estuaries, there is a pressing need to identify landward migration corridors and better quantify the potential for landward migration and coastal squeeze.

We quantified and compared the area available for landward migration of tidal saline wetlands and the area where urban development is expected to prevent migration for 39 estuaries along the wetland‐rich USA Gulf of Mexico coast. We did so under three sea level rise scenarios (0.5, 1.0, and 1.5 m by 2100).

Within the region, the potential for wetland migration is highest within certain estuaries in Louisiana and southern Florida (e.g. Atchafalaya/Vermilion Bays, Mermentau River, Barataria Bay, and the North and South Ten Thousand Islands estuaries).

The potential for coastal squeeze is highest in estuaries containing major metropolitan areas that extend into low‐lying lands. The Charlotte Harbor, Tampa Bay, and Crystal‐Pithlachascotee estuaries (Florida) have the highest amounts of urban land expected to constrain wetland migration. Urban barriers to migration are also high in the Galveston Bay (Texas) and Atchafalaya/Vermilion Bays (Louisiana) estuaries.

Synthesis and applications. Coastal wetlands provide many ecosystem services that benefit human health and well‐being, including shoreline protection and fish and wildlife habitat. As the rate of sea level rise accelerates in response to climate change, coastal wetland resources could be lost in areas that lack space for landward migration. Migration corridors are particularly important in highly urbanized estuaries where, due to low‐lying coastal development, there is not space for wetlands to move and adapt to sea level rise. Future‐focused landscape conservation plans that incorporate the protection of wetland migration corridors can increase the adaptive capacity of these valuable ecosystems and simultaneously decrease the vulnerability of coastal human communities to the harmful effects of rising seas.
Laparoscopic excision of a retroperitoneal schwannoma: A case report
Authors: Ohsawa Manato , Miguchi Masashi , Yoshimitsu Masanori , Oishi Koichi , Kohashi Toshihiko , Hihara Jun , Mukaida Hidenori , Kaneko Mayumi , Egi Hiroyuki , Ohdan Hideki , Hirabayashi Naoki 
Published: May 2018

AbstractSchwannomas are tumors originating from the Schwann cells of the peripheral nerve sheath. Only 1%–3% of schwannomas reportedly occur in the pelvis. In a 67‐year‐old man, a pelvic mass that was 52 mm in diameter was incidentally diagnosed during a preoperative CT evaluation for prostate cancer. Preoperative 3‐D reconstruction CT showed that the feeding artery to the tumor originated from the internal iliac artery and the drainage vein from the internal iliac vein. Each vessel could be isolated, clipped, and cut with minimal bleeding. The tumor was easily dissected from adjacent structures and was completely resected via laparoscopic surgery. Histopathology and immunohistochemistry of the excised specimen revealed a benign schwannoma. Using 3‐D reconstruction to recognize a tumor's positional relation with the supplying vessels is important for avoiding complications during laparoscopic resection in the narrow pelvis. Laparoscopic resection is safe, feasible, and effective for retroperitoneal schwannoma.
Short‐term ingestion of deoxynivalenol in naturally contaminated feed alters piglet performance and gut hormone secretion
Authors: Li Ruonan , Li Yansen , Su Yongteng , Shen Dan , Dai Pengyuan , Li Chunmei 
Published: May 2018

AbstractThe mycotoxin deoxynivalenol (DON) generally exists in cereals and affects human and animal health. The aim of this study is to analyze the impacts of DON in naturally contaminated feed on piglet growth performance and intestinal hormone secretion in the short term. We randomly divided 5‐week‐old piglets into four groups: Control, DON 1,000, DON 2,000 and DON 3,000 groups. Piglets received a feed naturally contaminated with DON (approximately 400, 1,000, 2,000 or 3,000 μg/kg) for 21 days. Body weight showed no significant difference following exposure to DON. The balance of anti‐oxidation and oxidation was disrupted by DON after 21 days. The concentration of tumor necrosis factor‐alpha (TNF‐α) and cyclooxgenase‐2 (COX‐2) significantly increased (p < .001) in all DON‐treated groups. Gut anorexigenic hormone secretion of peptide YY (PYY) and cholecystokinin (CCK) had a time‐ and dose‐dependent relationship with DON exposure; however, there was no effect on orexigenic hormone ghrelin secretion. Changes of histomorphology in the jejunum were observed in DON‐treated groups, including villi flattening and fusion, and apical necrosis of villi. These results indicated that DON could suppress piglet growth performance and alter gut hormone secretion in the short term.
Skeletal muscle and liver gene expression profiles in finishing steers supplemented with Amaize
Authors: Elolimy Ahmed A. , Moisá Sonia J. , Brennan Kristen M. , Smith Allison C. , Graugnard Daniel , Shike Daniel W. , Loor Juan J. 
Published: May 2018

AbstractOur main objective was to evaluate the effects of feeding α‐amylase (Amaize, Alltech Inc., Nicholasville, KY, USA) for 140 days on skeletal muscle and liver gene transcription in beef steers. Steers fed Amaize had lower average daily gain (p = .03) and gain:feed ratio (p = .05). No differences (p > .10) in serum metabolites or carcass traits were detected between the two groups but Amaize steers tended (p < .15) to have increased 12th rib fat depth. Microarray analysis of skeletal muscle revealed 21 differentially expressed genes (DEG), where 14 were up‐regulated and seven were down‐regulated in Amaize‐fed steers. The bioinformatics analysis indicated that metabolic pathways involved in fat formation and deposition, stress response, and muscle function were activated, while myogenesis was inhibited in Amaize‐fed steers. The quantitative PCR results for liver revealed a decrease (p < .01) in expression of fatty acid binding protein 1 (FABP1) and 3‐hydroxybutyrate dehydrogenase 1 (BDH1) with Amaize. Because these genes are key for intracellular fatty acid transport, oxidation and ketone body production, data suggest a reduction in hepatic lipid catabolism. Future work to investigate potential positive effects of Amaize on cellular stress response, muscle function, and liver function in beef cattle appears warranted.
Optimization of the in vitro fertilization protocol for frozen epididymal sperm with low fertilization ability in Ban—A native Vietnamese pigs
Authors: Linh Nguyen Viet , Somfai Tamas , Nguyen Thi Hiep , Nhung Nguyen Thi , Hong Nguyen Thi , Dat Nguyen Tien , Thinh Nguyen Hoang , Van Nguyen Khanh , Quyen Dong Van , Chu Hoang Ha , Son Nguyen Thanh , Kikuchi Kazuhiro 
Published: May 2018

AbstractThe aim of the present study was to improve the penetration during in vitro fertilization (IVF) of a frozen lot of epididymal sperm with a notoriously low fertilization ability of a Ban boar which is a native Vietnamese breed by optimizing different parameters of the IVF system. In Experiment 1, we determined that Pig‐fertilization medium was superior medium to Tyrode's albumin lactate pyruvate‐polyvinyl alcohol medium for IVF and defined the optimum the sperm concentration (1 × 106 sperm/ml). In Experiment 2, we clarified that partial removal of cumulus cells from cumulus‐oocyte complexes by hyaluronidase treatment before IVF enhances sperm penetration, whereas complete cumulus removal reduces penetration. Finally, in Experiment 3 the elevation of concentration of caffeine in Pig‐fertilization medium from 2 to 5 mmol/L and the prolongation of the co‐culture of gametes from 3 to 5 hr significantly increased the total penetration rate from 15.2% to over 50%. In conclusion, the combination of partial oocyte denudation, an elevated caffeine concentration in Pig‐fertilization medium and an extended interval of IVF with using an optimized sperm concentration was a potent way to improve the fertilization results for a frozen epididymal Ban sperm lot with low fertility.
Allogeneic haematopoietic cell transplantation for adult acute myeloid leukaemia in second remission: a retrospective study of the Adult Acute Myeloid Leukaemia Working Group of the Japan Society for Haematopoietic Cell Transplantation (JSHCT)
Authors: Konuma Takaaki , Yanada Masamitsu , Yamasaki Satoshi , Kuwatsuka Yachiyo , Fukuda Takahiro , Kobayashi Takeshi , Ozawa Yukiyasu , Uchida Naoyuki , Ota Shuichi , Hoshino Takumi , Takahashi Satoshi , Kanda Yoshinobu , Ueda Yasunori , Takanashi Minoko , Kanda Junya , Ichinohe Tatsuo , Atsuta Yoshiko , Yano Shingo 
Published: May 2018

SummaryTo evaluate the outcomes and prognostic factors following allogeneic haematopoietic cell transplantation (HCT) for adult acute myeloid leukaemia (AML) in second complete remission (CR2), we retrospectively analysed the Japanese registration data of 1080 adult AML patients in CR2 who had received allogeneic HCT. The probability of overall survival and the cumulative incidence of relapse at 3 years was 66% and 19%, respectively. In multivariate analysis, older age, poor cytogenetics and shorter duration of first complete remission were significantly associated with a higher overall mortality. Our data demonstrated the significant efficacy of allogeneic HCT for adult AML in CR2.
Outcome of patients with Myelofibrosis relapsing after allogeneic stem cell transplant: a retrospective study by the Chronic Malignancies Working Party of EBMT
Authors: McLornan Donal P. , Szydlo Richard , Robin Marie , van Biezen Anja , Koster Linda , Blok Henrik J. P. , Van Lint Maria T. , Finke Jürgen , Vitek Antonin , Carlson Kristina , Griskevicius Laimonas , Holler Ernst , Itälä‐Remes Maija , Schaap Michel , Socié Gerard , Bay Jacques‐Olivier , Beguin Yves , Bruno Benedetto , Cornelissen Jan J. , Gedde‐Dahl Tobias , Ljungman Per , Rubio Marie T. , Yakoub‐Agha Ibrahim , Klyuchnikov Evgeny , Olavarria Eduardo , Chalandon Yves , Kröger Nicolaus 
Published: May 2018

SummaryAllogeneic Haematopoietic Stem Cell Transplant (allo‐HSCT) remains the only curative approach for Myelofibrosis (MF). Scarce information exists in the literature on the outcome and, indeed, management of those MF patients who relapse following transplant. We hereby report on the management and outcome of 202 patients who relapsed post allo‐HSCT for MF.
How I manage patients with relapsed/refractory diffuse large B cell lymphoma
Authors: Gisselbrecht Christian , Van Den Neste Eric 
Published: May 2018

SummaryDespite progress in the upfront treatment of diffuse large B cell lymphoma (DLBCL), patients still experience relapses. Salvage chemotherapy followed by autologous stem cell transplantation (ASCT) is the standard second‐line treatment for relapsed and refractory (R/R) DLBCL. However, half of the patients will not be eligible for transplantation due to ineffective salvage treatment, and the other half will relapse after ASCT. In randomized studies, no salvage chemotherapy regimen is superior to another. The outcomes are affected by the secondary International Prognostic Index at relapse and various biological factors. The strategy is less clear in patients who require third‐line treatment. A multicohort retrospective non‐Hodgkin lymphoma research (SCHOLAR‐1) study conducted in 636 patients with refractory DLBCL showed an objective response rate of 26% (complete response 7%) to the next line of therapy with a median overall survival of 6·3 months. In the case of a response followed by transplantation, long‐term survival can be achieved in DLBCL patients. There is clearly a need for new drugs that improve salvage efficacy. Encouraging results have been reported with chimeric antigen receptor ‐T cell engineering, warranting further studies in a well‐defined control group of refractory patients. The Collaborative Trial in Relapsed Aggressive Lymphoma (CORAL) was used as a handy framework to build the discussion.