bluuebunny/crossref_metadata_2025_split huggingface dataset:
Objects in motion verb phrases
Authors: Biggs Alison 
Published: August 2019

This article investigates the syntactic and semantic relationship between the unselected object and the unergative verb in examples like Mary waltzed John around the room. Current consensus holds that this sentence involves resultative secondary predication, so that it is structurally equivalent to resultatives like Mary sang her throat hoarse. Yet it is well known that the waltz vs. sing verb phrase structures do not have the same argument or event structural interpretations. Notably the object with waltz seems to be an agent, while the object with sing is a patient or theme. Previous studies propose lexical rules of composition associated with waltz to specify the “special” interpretation of its object. In this article I show that the waltz object is not formally agentive, but has (what I call) an in motion interpretation. I further show that the waltz and sing verb phrases have different syntactic structures: the waltz verb phrase is transitive, and is not resultative. I argue that the contrast in interpretation between the object of waltz and sing (and the other differences in these clauses) follows from this structural difference, and that a lexical approach overgenerates. I conclude that the interpretation of the waltz object accords with regular rules of syntax-semantics correspondence.
n. 28 - OS PLANOS MUNICIPAIS DE EDUCAÇÃO NO CONTEXTO DO PNE 2014-2024: APONTAMENTOS SOBRE A IMPLEMENTAÇÃO DA POLÍTICA
Authors: Bastos Roberta Freire , Ferreira Eliza Bartolozzi 
Published: August 2019

Este texto tem como objetivo investigar as principais lógicas de ação desenvolvidas para a implementação dos planos de educação em municípios da Região Metropolitana da Grande Vitória. O ponto de partida é a contextualização do cenário das políticas educativas no país nos últimos anos, sobretudo no que concerne ao desmonte do Fórum Nacional de Educação (FNE) e a constituição de um Fórum com representação popular e Conferência igualmente democrática. Sob uma perspectiva de análise cognitiva das políticas públicas, este estudo terá como objetivo apresentar e discutir dados sobre a implementação de planos municipais de educação na Região Metropolitana da Grande Vitória. Apresenta-se a hipótese de que, na produção das regras do jogo, as três municipalidades investigadas (Cariacica, Serra e Vitória) apresentam lógicas de ação próprias para a construção e a realização de seus planos educacionais. Os procedimentos para análise de dados consistiram na observação partipante durante a constituição dos planos, realizada nos anos de 2014 e 2015, e na análise documental e conjuntural de seus processos de implementação no ano de 2018, a partir das Conferências Municipais de Educação. Planejamento educacional; Plano Municipal de Educação; Plano Nacional de Educação; Políticas educacionais.
n. 29 - A NOVA LEI DE GESTÃO DEMOCRÁTICA DA REDE PÚBLICA ESTADUAL DE EDUCAÇÃO BÁSICA DO ACRE E A MUDANÇA NO PERFIL DE DIRETOR ESCOLAR
Authors: De Melo Karolyne Borges , Melo Lúcia De Fátima , Damaceno Ednaceli Abreu 
Published: August 2019

O artigo faz uma análise da nova Lei de Gestão Democrática das unidades escolares da rede pública estadual de educação básica do Estado do Acre, Lei nº 3.141/2016, que substituiu a Lei nº 1.513/2003, dando ênfase a mudança no perfil do novo diretor escolar estadual, que passou a não exigir a formação docente para direção da escola. Para esta análise, é pertinente considerar o contexto de reforma vivida pelo Estado Brasileiro nas últimas décadas e as influências de tais reformas nas instituições e nos serviços públicos de natureza educacional, configurada na concepção de uma Nova Gestão Pública – NGP. A redução dos custos da gestão e a ampliação da produtividade na administração pública sob a lógica da iniciativa privada determinaram alterações relevantes na política educacional no Brasil, influenciando diretamente no funcionamento e na rotina das escolas e podem ser consideradas determinantes também nas reformas educacionais empreendidas no Acre. As bases teóricas se sustentam em Oliveira (2011), Ball (2004; 2005), Souza (2006), Paro (2015), dentre outras. A pesquisa seguiu uma abordagem qualitativa, de cunho bibliográfica e documental. Os aspectos conclusivos apontam que a mudança no perfil do diretor se constitui como inconstitucional, portanto, ilegal, além de um retrocesso histórico por desconsiderar e desvalorizar toda a luta pela formação docente no país e no Estado do Acre.
The Structural Relationship Model of Indicators of Mindful Leadership for Primary School Principals
Authors: Wongkom Sthian , Sanrattana Wirot , Chusorn Prayuth 
Published: August 2019

This study is a descriptive research study aiming to: 1) test the fitness between the theoretical model of the mindful leadership indicators and empirical data and 2) investigate factor loading value of the main elements, sub-elements, and indicators with models. The population of the research is 27,718 primary school principals under the office of the Basic Education Commission. Data collection means was rating-scale questionnaire from 610 participants in the sample group selected randomly by a multi-stage sampling technique. The data was analysed using a computer program. The results of the research confirmed the hypotheses of the research which are: the theoretical model is relevant to the empirical data, and the value of Relative Chi-Square (CMIN/DF), Root Mean Square Error of Approximation (RMSEA), Goodness-of-Fit Index (GFI), Adjusted Goodness-of-Fit Index (AGFI), Comparative Fit Index (CFI), and (6) Normed Fit Index (NFI) is in accordance with the criteria and 2) the value of factor loading of the main elements is between 0.84 – 1.70 which is 0.70 higher than the criteria, the value of factor loading of the sub-elements is between 0.31 – 1.95, and the value of the factor loading of the indicators is between 0.30 – 8.26 which is 0.30 higher than the criteria.
How to Supervise International PhD Students: A Narrative Inquiry Study
Authors: Hussain Mudassir , Ali Hashim 
Published: August 2019

This narrative inquiry study was undertaken, recruiting 06 successful PhD students in China. The participants were invited and semi-structured interviews were taken one-by-one. The study aimed to explore information about supervisor-supervisee relationship and factors that motivate international PhD students to enhance their research outcomes in a cross-cultural environment. The qualitative data were coded, using QDA miner lite software. After the formation of initial codes, five major categories were emerged included: empowerment, usefulness, success, interest and caring. Each category represented the respective component of MUSIC model of academic motivation (Jones, 2009). The findings illustrated that International PhD students are satisfied with work and life. The supervisors used effective strategies to motivate international PhD supervisees to enhance academic outcomes. The study uncovered students’ expectations which included: formal meetings, feedback, guidance, and team work. Based on study findings and results, the MUSIC model can be used as supervision strategy. It is a comprehensive model where all of its five components cover the supervisees’ expectations.
Therapeutic effect of Bacillus Calmette–Guerin polysaccharide nucleic acid on mast cell at the transcriptional level
Authors: Yan Siyu , Liu Runqiu , Mao Manyun , Liu Zhaoqian , Zhang Wei , Zhang Yi , Li Jie , Peng Cong , Chen Xiang 
Published: August 2019

Background
Chronic spontaneous urticaria (CSU) is a common and recurrent autoimmune-related disease with unclear pathogenesis. Dysfunction of immune cells, such as T cells, mast cells, and basophils, is involved. Bacillus Calmette–Guerin polysaccharide nucleic acid (BCG–PSN), an immunomodulator partially extracted from BCG, can be used in the combined treatment of CSU with an unknown mechanism.

Methods
To study the therapeutic effect and mechanism of BCG–PSN on CSU, we initially assessed the clinical efficacy in 110 enrolled CSU patients of 4-week antihistamine monotherapy vs. antihistamine plus BCG–PSN combined therapy. Subsequently, to explore the further mechanism of BCG-PSN, the mast cell line RBL-2H3 pretreated with BCG-PSN was used to evaluate the transcriptional expression profiles via lncRNA sequencing. Real time PCR was conducted to validate the candidate gene expression.

Results
We found no significant difference in treatment efficacy between the BCG–PSN group (71.7%) and the monotherapy group (71.9%). However, the average time of complete relief in the BCG–PSN group was significantly shorter than that in the monotherapy group (36.77 ± 17.33 vs. 51.27 ± 16.80, p = 0.026). In vitro experiments showed that BCG-PSN inhibited β-hexosaminidase release rates in IgE-sensitized RBL-2H3 cells (p < 0.001). Sequencing data revealed the expression profiles of functional genes, including a significant decrease in Erb-B2 receptor tyrosine kinase 4, which can be regulated by the nuclear factor kappa B (NF-κB) pathway.

Discussion
CSU is a chronic, recurrent disease with complex pathogenesis. Mast cells and basophils are the primary target cells of the disease. BCG–PSN decrease the β-HEX release rates and regulated IgE-mediated mast cell activation in RBL-2H3 cells by mediating immune-related gene expression including ERBB4. These findings suggest that BCG–PSN may mediate ERBB4 expression via the NF-κB pathway and may have value in the treatment of CSU.
Molecular Detection of Extended Spectrum Beta-lactamase Resistance in Escherichia coli from Poultry Droppings in Keffi, Nigeria
Authors: Tama S. C. , Ngwai Y. B. , Nkene I. H. , Abimiku R. H. 
Published: August 2019

Objectives: The present study reports extended-spectrum beta-lactamase (ESBL) production in E. coli isolates from poultry droppings from selected poultry farms in Keffi, Nigeria.
Methods: Seventy-five (75) samples of poultry droppings were collected, and E. coli was isolated using standard microbiological methods. Antibiotic susceptibility testing and minimum inhibitory concentrations were evaluated as described by the Clinical and Laboratory Standards Institute (CLSI). Phenotypic confirmation of ESBL production by the isolates was carried out using double disc synergy test. Molecular detection of ESBL genes was carried out using Polymerase Chain Reaction (PCR) method.
Results: All (100%) samples had E. coli. Antimicrobial resistance in the isolates were as follows: imipenem (12.0%), gentamicin (20.0%), cefoxitin (37.3%), cefotaxime (41.3%), ceftazidime (44.0%), ciprofloxacin (48.0%), amoxicillin/clavulanic acid (58.7%), streptomycin (92.0%), sulphamethoxazole/trimethoprim (92.0%) and ampicillin (98.7%). Joint resistance to ampicillin, sulphamethoxazole/trimethoprim-streptomycin was the commonest resistance phenotype at 10.6%. Multiple antibiotic resistance (MAR) was observed in 97.3% (73/75) of the isolates; and the most common MAR indices were 0.7 (21.9%), 0.5 (17.8%), 0.4 (16.4%), 0.8 (11.1%) and 0.3 (10.9%). Twenty three (46.9%) of the 49 cefotaxime/ceftazidime isolates were confirmed ESBL producers. Twenty-two of the 23 ESBL positive isolates (95.7%) carried the bla genes as follows: 95.5% (21/22) for blaSHV; 68.2% (15/22) for blaTEM; and 50.0% (11/22) for blaCTX-M. Eleven (50%) of the 22 isolates carried two bla genes (blaSHV and blaCTX-M, blaTEM and blaCTX-M and blaTEM and blaSHV).
Conclusion: The E. coli isolates were less resistant to imipenem, gentamicin and cefoxitin; most isolates were MAR, with resistance to 7 antibiotics being the most predominant. In addition, the blaSHV gene was the most common ESBL gene detected in confirmed ESBL-producing E. coli isolates.
Some accuracy related aspects in two‐fluid hydrodynamic sub‐grid modeling of gas–solid riser flows
Authors: Mouallem Joseph , Niaki Seyed R. A. , Chavez‐Cussy Norman , Milioli Christian C. , Milioli Fernando E. 
Published: August 2019

AbstractSub‐grid closures for filtered two‐fluid models (fTFM) useful in large scale simulations of riser flows can be derived from highly resolved simulations (HRS) with microscopic two‐fluid modeling (mTFM). Accurate sub‐grid closures require accurate mTFM formulations as well as accurate correlation of relevant filtered parameters to suitable independent variables. This article deals with both of those issues. The accuracy of mTFM is touched by assessing the impact of gas sub‐grid turbulence over HRS filtered predictions. A gas turbulence alike effect is artificially inserted by means of a stochastic forcing procedure implemented in the physical space over the momentum conservation equation of the gas phase. The correlation issue is touched by introducing a three‐filtered variable correlation analysis (three‐marker analysis) performed under a variety of different macro‐scale conditions typical or risers. While the more elaborated correlation procedure clearly improved accuracy, accounting for gas sub‐grid turbulence had no significant impact over predictions.
Multistage adaptive optimization using hybrid scenario and decision rule formulation
Authors: Motamed Nasab Farough , Li Zukui 
Published: August 2019

AbstractScenario‐based stochastic programming and linear decision rule (LDR)‐based robust optimization are prevalent methods for solving multistage adaptive optimization (MSAP) problems. In practical applications such as capacity expansion planning of chemical processes, often multiple sources of uncertainty affect the problem which introduces challenges to traditional stochastic optimization methods. While a large number of uncertain parameters exist in the problem, using scenario‐based method results in very large problem size and the solution becomes computationally expensive. In addition, when the constraints include multiplication of uncertain parameters and adaptive variables, the constraints are not linear with respect to uncertain parameters when the LDR method is used. In order to address these challenges, we propose two different hybrid methods where scenario and decision rule methods are combined to solve the MSAP problem. The article demonstrates the computational performance of the proposed hybrid methods using two chemical process planning examples.
Impact of margin status on survival after surgery for sinonasal squamous cell carcinoma
Authors: Jafari Aria , Shen Sarek A. , Qualliotine Jesse R. , Orosco Ryan K. , Califano Joseph A. , DeConde Adam S. 
Published: August 2019

BackgroundSinonasal squamous cell carcinoma (SNSCC) is the most common malignancy of the paranasal sinuses. Surgery is the mainstay of treatment, yet positive surgical margins (PSM) are common and the prognostic impact on overall survival (OS) is mixed. Given the heterogeneity of impact of PSM on OS within the literature, we hypothesized that extent of tumor extirpation (microscopic PSM vs macroscopic PSM) may play a role in OS.MethodsPatients with SNSCC were identified in the National Cancer Database (NCDB, n = 7808). Of these, 4543 patients underwent surgery, 3265 patients underwent nonsurgical therapy. Kaplan‐Meier curves were used to compare OS between negative surgical margin (NSM), micro‐PSM, and macro‐PSM cohorts vs patients undergoing primary nonsurgical therapy in a propensity‐score‒matched analysis. Multivariable analysis of factors associated with macro‐PSM was also performed.ResultsOne thousand thirty‐three (22.0%) of the surgery patients had PSM, and approximately half (n = 521, 50.6%) of these had macro‐PSM. When compared with nonsurgical treatment, propensity‐score‒matched results demonstrated improved OS in patients with NSM and micro‐PSM (p < 0.001), but macro‐PSM patients did not demonstrate improvement (p = 0.20). Tumor within the paranasal sinuses and advanced nodal classification (N2/N3) (odds ratio [OR], 1.18; p = 0.02; and OR, 15.09; p = 005, respectively) was associated with increased odds of macro‐PSM on multivariable analysis.ConclusionWe demonstrate that the degree of tumor extirpation correlates with OS. Macro‐PSM did not confer a benefit to OS when compared with nonsurgical therapy, and factors including tumor location and advanced nodal status affect whether surgery will result in macro‐PSM. Given these findings, informed, shared decisionmaking between patient and surgeon regarding nonsurgical alternatives should occur before electing to proceed with surgery in SNSCC.
High Catalytic Performance of Mesoporous Dual Brønsted Acidic Ternary Poly (Ionic Liquids) for Friedel‐Crafts Alkylation
Authors: Sha Xiao , Sheng Xiaoli , Zhou Yuming , Wang Beibei , Liu Yonghui , Bao Jiehua 
Published: August 2019

A newfangled cross‐linked dual Brønsted acidic ternary mesoporous poly (ionic liquids)(MPILs) with mesoporous structure was successfully synthesized with divinylbenzene as cross linker, 1‐vinyl‐3‐butyl imidazole bromide and sodium p‐styrene sulfonate as functional group through an ordinary post‐modification method and anion exchange process. A sponge‐like mesoporous tunnel structure was observed and the obtained P (BVS‐SO3H)‐SO3CF3 sample appeared a relatively high thermal stability, a large surface area (up to 286.8 m2/g) and great pore volume (0.73 cm3/g). The abundant dual acidic group of sulfonic acid and trifluoromethanesulfonic acid of the composite in the polymer framework impart Brønsted acidity. For the sake of demonstrating our claims, the sample has been used as a novel solid acid catalyst for the reaction of alkylation of o‐xylene with styrene to 1‐diphenylethane (PXE). Under optimal reaction conditions (reaction under 120 °C for 3 hr, catalyst amount was 0.5 wt% of the reaction system, and the mass ratio of o‐xylene/styrene was 7.5:1, a 100% conversion of styrene and 93.7% PXE yield was acquired. After four times recycle, the yield remains 53.3%. Comparing with the commercial liquid acid catalyst, it processing a higher catalytic property and recyclability. Moreover, this fresh dual acidic heterogeneous catalyst owning a promising future applied in other acidic catalytic reactions and provide a new method to modify catalyst.
Organometallic assembling of chitosan‐Iron oxide nanoparticles with their antifungal evaluation againstRhizopus oryzae
Authors: Saqib Saddam , Zaman Wajid , Ullah Fazal , Majeed Imran , Ayaz Asma , Hussain Munis Muhammad Farooq 
Published: August 2019

The ever‐increasing resistance of plant microbes towards fungicides and bactericides has been causing serious threat to plant production in recent years. For the development of an effective antifungal agent, we introduce a novel hydrothermal protocol for synthesis of chitosan iron oxide nanoparticles (CH‐Fe2O3NPs) using acetate buffer of low pH 5.0 for intermolecular interaction of Fe2O3NPs and CH. The composite structure and elemental elucidation were carried out by using X‐ray power diffraction (XRD), Scanning Electron Microscopy (SEM), Energy Dispersive X‐ray (EDX), Transmission Electron Microscopy (TEM), Fourier Transformed Infrared Spectroscopy (FTIR) and Ultraviolet Visible Absorption Spectroscopy (UV–vis spectroscopy). Additionally, antifungal activity was evaluated bothIn vitroandIn vivoagainstRhizopus oryzaewhich is causing fruit rot disease of strawberry. We compared different concentrations (0.25%, 0.50%, 075% and 1%) of CH‐Fe2O3NPs and 50% synthetic fungicide (Matalyxal Mancozab) to figure out suitable concentration for application in the field. XRD analysis showed a high crystalline nature of the NPs with average size of 52 nanometer (nm). SEM images revealed spherical shape with size range of 50–70 nm, whereas, TEM also revealed spherical shape, size ranging from 0 nm to 80 nm. EDX and FTIR results revealed presence of CH on surface of Fe2O3NPs. The band gap measurement showed peak 317–318 nm for bare Fe2O3NPs and CH‐Fe2O3NPs respectively. Antifungal activity in bothIn vitroandIn vivosignificantly increased with increase in concentration. The overall results revealed high synergetic antifungal potential of organometallic CH‐Fe2O3NPs againstRhizopus oryzaeand suggest the use of CH‐Fe2O3NPs against other Phyto‐pathological diseases due to biodegradable nature.
UV‐curing behavior of unsaturated cyclohexanone formaldehyde resins with thiols
Authors: Xu Peng , Li Chaofeng , Chang Xinwei , Zhang Yanwu 
Published: August 2019

ABSTRACTNumerous researches about the modification and application of cyclohexanone formaldehyde resins (CFR) have been conducted, few of them involve in the UV‐curing of unsaturated CFR with thiols. Thus, CFR are synthesized using the rehydrated magnesium‐aluminum hydrotalcite as the catalyst and double bonds are introduced by capping the chain ends with 5‐norbornene‐2,3‐dicarboxylic anhydride. Through monitoring the conversion of double bonds with FTIR, the UV‐curing behavior of unsaturated CFR in the presence of pentaerythritol tetra (3‐mercaptopropionate) is studied. The results show that the conversion of double bonds can reach to 64.1% at 0.66 mW cm−2 of UV light intensity when the molar ratio of double bonds to sulfhydryl groups is 1:1 in the presence of benzoin dimethyl ether (1% of molar amount of double bonds). Considering the similarity between UV‐curing of thiols‐double bonds and thermo‐curing of amine‐epoxy, one diffusion controlled kinetics model is derived and it shows good fitness. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48420.
Early MRI predictors of disease-free survival in locally advanced rectal cancer from the GRECCAR 4 trial
Authors: Nougaret S , Castan F , Forges H , Vargas H A , Gallix B , Gourgou S , Rouanet P , Rullier E , Lelong B , Maingon P , Tuech J-J , Pezet D , Rivoire M , Meunier B , Loriau J , Valverde A , Fabre J-M , Prudhomme M , Cotte E , Portier G , Quero L , Gallix B , Lemanski C , Ychou M , Bibeau F 
Published: August 2019

Abstract

Background
Tailored neoadjuvant treatment of locally advanced rectal cancer (LARC) may improve outcomes. The aim of this study was to determine early MRI prognostic parameters with which to stratify neoadjuvant treatment in patients with LARC.

Methods
All patients from a prospective, phase II, multicentre randomized study (GRECCAR4; NCT01333709) were included, and underwent rectal MRI before treatment, 4 weeks after induction chemotherapy and after completion of chemoradiotherapy (CRT). Tumour volumetry, MRI tumour regression grade (mrTRG), T and N categories, circumferential resection margin (CRM) status and extramural vascular invasion identified by MRI (mrEMVI) were evaluated.

Results
A total of 133 randomized patients were analysed. Median follow-up was 41·4 (95 per cent c.i. 36·6 to 45·2) months. Thirty-one patients (23·3 per cent) developed tumour recurrence. In univariable analysis, mrEMVI at baseline was the only prognostic factor associated with poorer outcome (P = 0·015). After induction chemotherapy, a larger tumour volume on MRI (P = 0·019), tumour volume regression of 60 per cent or less (P = 0·002), involvement of the CRM (P = 0·037), mrEMVI (P = 0·026) and a poor mrTRG (P = 0·023) were associated with poor outcome. After completion of CRT, the absence of complete response on MRI (P = 0·004), mrEMVI (P = 0·038) and a poor mrTRG (P = 0·005) were associated with shorter disease-free survival. A final multivariable model including all significant variables (baseline, after induction, after CRT) revealed that Eastern Cooperative Oncology Group performance status (P = 0·011), sphincter involvement (P = 0·009), mrEMVI at baseline (P = 0·002) and early tumour volume regression of 60 per cent or less after induction (P = 0·007) were associated with relapse.

Conclusion
Baseline and early post-treatment MRI parameters are associated with prognosis in LARC. Future preoperative treatment should stratify treatment according to baseline mrEMVI status and early tumour volume regression.