bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variation motivated by analogy with fixed chunks
Authors: Szczesniak Konrad 
Published: July 2019

AbstractThis study looks at the variable use of two related forms, namely the reflexive construction (The defendant talked himself into trouble) and thewayconstruction (The actress danced her way to stardom). Despite their differences, the two constructions are often used in ways that can be described as one taking over the other’s expressive functions. FollowingMondorf (2011), I assume that the variation results in part from the historical competition between the two, and from the fact that the process of specialization is not yet complete. I present another factor responsible for the overlap, which may keep the specialization from ever being concluded. It involves specific uses of a construction chunked into formulaic phrases (liketalk oneself into trouble) which are used reversively (talk oneself out of trouble) against the specifications of the construction they are based on. That is, the kind of variation discussed here is set in motion by the same mechanism observed in novelty motivated through local analogies with specific expressions and low-level instances of a construction.
Computational methods in the study of self-entangled proteins: a critical appraisal
Authors: Perego Claudio , Potestio Raffaello 
Published: July 2019

Abstract
The existence of self-entangled proteins, the native structure of which features a complex topology, unveils puzzling, and thus fascinating, aspects of protein biology and evolution. The discovery that a polypeptide chain can encode the capability to self-entangle in an efficient and reproducible way during folding, has raised many questions, regarding the possible function of these knots, their conservation along evolution, and their role in the folding paradigm. Understanding the function and origin of these entanglements would lead to deep implications in protein science, and this has stimulated the scientific community to investigate self-entangled proteins for decades by now. In this endeavour, advanced experimental techniques are more and more supported by computational approaches, that can provide theoretical guidelines for the interpretation of experimental results, and for the effective design of new experiments. In this review we provide an introduction to the computational study of self-entangled proteins, focusing in particular on the methodological developments related to this research field. A comprehensive collection of techniques is gathered, ranging from knot theory algorithms, that allow detection and classification of protein topology, to Monte Carlo or molecular dynamics strategies, that constitute crucial instruments for investigating thermodynamics and kinetics of this class of proteins.
Scaling behaviour of non-equilibrium planar N-atic spin systems under weak fluctuations
Authors: Sartori Pablo , Lee Chiu Fan 
Published: July 2019

Abstract
Starting from symmetry considerations, we derive the generic hydrodynamic equation of non-equilibrium XY spin systems with N-atic symmetry under weak fluctuations. Through a systematic treatment we demonstrate that, in two dimensions, these systems exhibit two types of scaling behaviours. For N = 1, they have long-range order and are described by the flocking phase of dry polar active fluids. For all other values of N, the systems exhibit quasi long-range order, as in the equilibrium XY model at low temperature.
Optimizing performance of Li4Ti5O12 nanorod doped C@ZnO by hydrothermal synthesis as half-cell lithium-ion battery anode
Authors: Priyono B , Nugraha M R , Syahrial A Z , Faizah  , Subhan A 
Published: July 2019

Abstract
Lithium titanate, Li4Ti5O12 (LTO) is a promising candidate as lithium ion battery anode material. In this investigation, LTO/C@ZnO was synthesized with LTO nanorod by hydrothermal method using TiO2 xerogel that prepared by the sol-gel method, lithium hydroxide (LiOH), Activated carbon, and Zinc Oxide (ZnO) nanorod. Three variations of ZnO content addition in weight %, i.e., 4, 7 and 10%, labelled as sample LTO/C@ZnO-4, LTO/C@ZnO-7 and LTO/C@ZnO-10, respectively. The characterizations were made using XRD, FE-SEM, and BET testing. These were performed to observe the effect of ZnO addition on structure, morphology, and surface area of the resulting samples. Result showed that the optimum discharge capacity from each samples was 32.84 mAh/g in LTO/C@ZnO-4 with the crystallite size of 11.86 nm and the surface area of 348.736 m2/g. In cyclic voltammetry testing, it shows a shift in reaction voltage and reduction in capacity that caused by the addition of C@ZnO and the lack of Li4Ti5O12 that are formed.
Synthesis and characterization of nano rosette TiO2 and CH3NH3PbCl2I for potential use in perovskite solar cell
Authors: Sofyan N , Ridhova A , Salman  , Yuwono A H , Udhiarto A 
Published: July 2019

Abstract
The characteristics of nano rosette TiO2 hydrothermally grown on a glass substrate with potential application in perovskite solar cell has been examined. Nano rosette TiO2 was synthesized through deposition on top of a fluorine-doped tin oxide glass substrate via hydrothermal reaction at 170°C for 6 hours. Formation and growth mechanism were characterized using X-ray diffraction (XRD), whereas the morphology was examined using a field emission scanning electron microscope (FE-SEM). The results showed that the formation of nano rosette TiO2 has been completed after 6 hours. Structural study from X-ray diffraction also showed that the crystal structure formation has been completed after 6 hours. This nano rosette TiO2 was tested for its performance as an electron transport layer (ETL) in the perovskite solar cell device. For this purpose, the perovskite CH3NH3PbCl2I 0.8 M was deposited on top of the ETL layer and the performance was tested using a semiconductor parameter analyser (SPA). The result showed an efficiency of about 3.4%, which is promising for the next development.
Derivation of Time-Activity Data Using Wearable Cameras and Measures of Personal Inhalation Exposure among Workers at an Informal Electronic-Waste Recovery Site in Ghana
Authors: Laskaris Zoey , Milando Chad , Batterman Stuart , Mukherjee Bhramar , Basu Niladri , O’neill Marie S , Robins Thomas G , Fobil Julius N 
Published: July 2019

Abstract

Objectives
Approximately 2 billion workers globally are employed in informal settings, which are characterized by substantial risk from hazardous exposures and varying job tasks and schedules. Existing methods for identifying occupational hazards must be adapted for unregulated and challenging work environments. We designed and applied a method for objectively deriving time-activity patterns from wearable camera data and matched images with continuous measurements of personal inhalation exposure to size-specific particulate matter (PM) among workers at an informal electronic-waste (e-waste) recovery site.

Methods
One hundred and forty-two workers at the Agbogbloshie e-waste site in Accra, Ghana, wore sampling backpacks equipped with wearable cameras and real-time particle monitors during a total of 171 shifts. Self-reported recall of time-activity (30-min resolution) was collected during the end of shift interviews. Images (N = 35,588) and simultaneously measured PM2.5 were collected each minute and processed to identify activities established through worker interviews, observation, and existing literature. Descriptive statistics were generated for activity types, frequencies, and associated PM2.5 exposures. A kappa statistic measured agreement between self-reported and image-based time-activity data.

Results
Based on image-based time-activity patterns, workers primarily dismantled, sorted/loaded, burned, and transported e-waste materials for metal recovery with high variability in activity duration. Image-based and self-reported time-activity data had poor agreement (kappa = 0.17). Most measured exposures (90%) exceeded the World Health Organization (WHO) 24-h ambient PM2.5 target of 25 µg m−3. The average on-site PM2.5 was 81 µg m−3 (SD: 94). PM2.5 levels were highest during burning, sorting/loading and dismantling (203, 89, 83 µg m−3, respectively). PM2.5 exposure during long periods of non-work-related activities also exceeded the WHO standard in 88% of measured data.

Conclusions
In complex, informal work environments, wearable cameras can improve occupational exposure assessments and, in conjunction with monitoring equipment, identify activities associated with high exposures to workplace hazards by providing high-resolution time-activity data.
Ethical and policy issues raised by uterus transplants
Authors: O’Donovan Laura , Williams Nicola Jane , Wilkinson Stephen 
Published: July 2019

AbstractIntroductionIn 2014, Brännström and colleagues reported the first human live birth following uterine transplantation (UTx). Research into this treatment for absolute uterine factor infertility has since grown with clinical trials currently taking place across centers in at least thirteen countries worldwide.Sources of dataThis review summarizes and critiques the academic literature on ethical and policy issues raised by UTx.Areas of agreementThere is general agreement on the importance of risk reduction and, in principle, to the sharing and maintenance of patient data on an international registry.Areas of controversyThere are numerous areas of controversy ranging from whether it is ethically justified to carry out uterus transplants at all (considering the associated health risks) to how deceased donor organs for transplant should be allocated. This review focuses on three key issues: the choice between deceased and living donors, ensuring valid consent to the procedure and access to treatment.Growing pointsUTx is presently a novel and rare procedure but is likely to become more commonplace in the foreseeable future, given the large number of surgical teams working on it worldwide.Areas timely for developing researchUterus transplantation requires us to re-examine fundamental questions about the ethical and social value of gestation. If eventually extended to transgender women or even to men, it may also require us to reconceptualize what it is to be a ‘father’ or to be a ‘mother’, and the definition of these terms in law.
Coming off cannabis: a cognitive and magnetic resonance imaging study in patients with multiple sclerosis
Authors: Feinstein Anthony , Meza Cecilia , Stefan Cristiana , Staines Richard W. 
Published: July 2019

AbstractCognitive dysfunction affects 40–80% of patients with multiple sclerosis. Smoking cannabis may add to these deficits. It is unclear whether coming off cannabis results in cognitive improvement. To address this question, 40 patients with multiple sclerosis who started using cannabis after the onset of multiple sclerosis and who used it for at least 4 days a week over many years were divided by odd-even number selection into two groups: cannabis continuation and cannabis withdrawal. Assessments took place at baseline and after 28 days and included serial versions of the Brief Repeatable Neuropsychological Battery for multiple sclerosis containing tests of verbal and visual memory, processing speed and executive function; structural and functional MRI, the latter entailing a compatible version of the Symbol Digit Modalities Test; urine for cannabinoid metabolites to detect compliance with abstinence. Only those participants deemed globally impaired at baseline (failure on at least two cognitive domains) were enrolled. The results revealed that the two groups were well matched demographically and neurologically. One subject was removed from the withdrawal group because of failed abstinence. Urine analysis revealed the cannabinoid consumed was predominantly tetrahydrocannabinol (THC). There were no baseline between group cognitive differences, but by Day 28 the withdrawal group performed significantly better on every cognitive index (P < 0.0001 for all). Significant within group differences were present for every test over time, but only in the abstinent group (P < 0.0001 for all tests). There were no between group baseline or Day 28 differences in structural MRI indices (global atrophy, total T1 and T2 lesion volume). At index assessment the two groups had a similar performance on the functional MRI-compatible Symbol Digit Modalities Test and there were no group differences in brain activation. However, by Day 28, the withdrawal group completed more trials correctly (P < 0.012) and had a faster reaction time (P < 0.002), associated with significantly increased activation in brain regions known to be associated with performance of the test (bilateral inferior frontal gyri, caudate and declive/cerebellum, P < 0.001 for all regions). These results reveal that patients with multiple sclerosis who are frequent, long-term cannabis users can show significant improvements in memory, processing speed and executive function after 28 days of drug abstinence. The absence of similar improvements in a matched multiple sclerosis group that remained on cannabis shows that beneficial cognitive change after stopping cannabis is not solely attributable to the effects of practice.
Epigenetic Markers of Aging Predict the Neural Oscillations Serving Selective Attention
Authors: Wiesman Alex I , Rezich Michael T , O’Neill Jennifer , Morsey Brenda , Wang Tina , Ideker Trey , Swindells Susan , Fox Howard S , Wilson Tony W 
Published: July 2019

Abstract
Chronological age remains an imperfect measure of accumulated physiological stress. Biological measures of aging may provide key advantages, allowing scientists focusing on age-related functional changes to use metrics derived from epigenetic factors like DNA methylation (DNAm), which could provide greater precision. Here we investigated the relationship between methylation-based age and an essential cognitive function that is known to exhibit age-related decline: selective attention. We found that DNAm-age predicted selective attention abilities and fully mediated the relationship between selective attention and chronological age. Using neuroimaging with magnetoencephalography, we found that gamma activity in the anterior cingulate was robustly predicted by DNAm-derived biological age, revealing the neural dynamics underlying this DNAm age-related cognitive decline. Anterior cingulate gamma activity also significantly predicted behavior on the selective attention task, indicating its functional relevance. These findings suggest that DNAm age may be a better predictor of cognitive and brain aging than more traditional chronological metrics.
Disrespectful treatment in primary care in rural Tanzania: beyond any single health issue
Authors: Larson Elysia , Mbaruku Godfrey , Kujawski Stephanie A , Mashasi Irene , Kruk Margaret E 
Published: July 2019

Abstract
Knowing how patients are treated in care is foundational for creating patient-centred, high-quality health systems and identifying areas where policies and practices need to adapt to improve patient care. However, little is known about the prevalence of disrespectful treatment of patients in sub-Saharan Africa outside of maternity care. We used data from a household survey of 2002 women living in rural Tanzania to describe the extent of disrespectful care during outpatient visits, who receive disrespectful care, and determine the association with patient satisfaction, rating of quality and recommendation of the facility to others. We asked about women’s most recent outpatient visit to the local clinic, including if they were made to feel disrespected, if a provider shouted at or scolded them, and if providers made negative or disparaging comments about them. Women who answered yes to any of these questions were considered to have experienced disrespectful care. We report risk ratios with standard errors clustered at the facility level. The most common reasons for seeking care were fever or malaria (33.9%), vaccination (33.6%) and non-emergent check-up (13.4%). Disrespectful care was reported by 14.3% of women and was more likely if the visit was for sickness compared to a routine check-up [risk ratio (RR): 1.6, 95% confidence interval (CI): 1.1–2.2]. Women who did not report disrespectful care were 2.1 times as likely to recommend the clinic (95% CI: 1.6–2.7). While there is currently a lot of attention on disrespectful maternity care, our results suggest that this is a problem that goes beyond this single health issue and should be addressed by more horizontal health system interventions and policies.
‘Not in the room, but the doctors were’: an Australian story-completion study about consumer representation
Authors: Scholz Brett , Bocking Julia , Hedt Peter , Lu Vinh N , Happell Brenda 
Published: July 2019

Abstract
Current mental health policy requires consumer involvement in all levels of health service management (i.e. planning, implementation, delivery and evaluation). However, current models often limit consumers to ‘representation’ roles that are criticized for silencing consumer views. This study compares understandings of consumer representatives’ and health professionals’ participation in decision-making processes in the mental health sector in Australia. Story completion methods were employed, with 34 participants (21 consumers, 8 health professionals and 5 people identifying both as consumer and health professional) completing a story stem about either a consumer representative or a health professional changing a committee meeting agenda. Using a thematic approach, three overarching themes were developed: how consumer representative roles remain unvalued, how such lack of value translates to not achieving co-production and how consumer representative roles can be better supported through allyship or subversion against organizational cultural norms. Findings suggest that organizational cultural norms in health settings need to be more inclusive of consumers to maximize the benefits of partnerships and fulfil policy expectations. Two methods for greater empowerment of consumers working in mental health are through allyship with non-consumer health professionals who support the goals of the consumer movement, and subversion of current practices.
Genetic and pharmacological inactivation of d-alanylation of teichoic acids sensitizes pathogenic enterococci to β-lactams
Authors: Coupri Delphine , Budin-Verneuil Aurélie , Hartke Axel , Benachour Abdellah , Léger Loïc , Lequeux Thierry , Pfund Emmanuel , Verneuil Nicolas 
Published: July 2019

AbstractBackgroundEnterococci intrinsically resistant to cephalosporins represent a major cause of healthcare-associated infections, and the emergence of MDR makes therapeutic approaches particularly challenging.ObjectivesTeichoic acids are cell wall glycopolymers present in Gram-positive bacteria. Teichoic acids can be modified by d-alanylation, which requires four proteins encoded by the dltABCD operon. Our objective was to evaluate the Dlt system as a druggable target to treat enterococcal infections.MethodsThe susceptibility of a d-alanylation-deficient strain of Enterococcus faecalis to β-lactam antibiotics individually and/or in combination was analysed. Moreover, a DltA inhibitor was synthesized to test pharmacological inhibition of d-alanylation in vivo and in host using the animal model Galleria mellonella with different clinical isolates of E. faecalis and Enterococcus faecium.ResultsMost cephalosporins used as mono treatment had no impact on survival of the parental strain, but were slightly lethal for the dltA mutant of E. faecalis. Addition of a very low concentration of amoxicillin significantly increased killing of the dltA mutant under these conditions. The most spectacular effect was obtained with a combination of cefotaxime (1 mg/L) and amoxicillin (0.03 mg/L). In the presence of the inhibitor, the WT strain was as susceptible to this combination treatment as the dltA mutant. This molecule associated with the antibiotics was also effective in killing other E. faecalis clinical isolates and successfully prevented death of Galleria infected with either E. faecalis or E. faecium.ConclusionsThe combined results support the potential usefulness of the Dlt system as a target to potentiate antibiotic combination therapies for the treatment of drug-resistant enterococci.
Detecting the Boundaries of Disposition Bias on Moral Judgments of Media Characters’ Behaviors using Social Judgment Theory
Authors: Matthews Nicholas L 
Published: July 2019

Abstract
eople continuously morally judge the behaviors of media characters. This informs people’s dispositions toward characters. Their dispositions bias their subsequent moral judgments of behavior. Affective disposition theory (ADT) contends that limits to disposition bias exist, but empirical evidence is absent. Three experiments tested the utility of using the ordered alternatives procedure (OAP) from social judgment theory to observe character disposition bias boundaries. Studies 1 and 2 explored and refined methods for detecting the bounds of disposition biases on moral judgments. Study 3 observed the boundaries using preregistered hypotheses, analyses, and sampling. Findings reveal the pragmatic nature of disposition bias, indicating a dependency on the magnitude of moral violation. This outcome interacted with role (average person vs. hero-based roles), schema (pure heroes vs. morally ambiguous characters), and exemplification (prototypes vs. exemplars). Findings corroborate ADT, Raney’s extension of ADT, and Sanders’ character impression formation model, and demonstrate the OAP’s utility for broader communication research.
Database thinking and deep description: designing a digital archive of the National Synchrotron Light Source
Authors: Crease Robert , Graham Elyse , Folsom Jamie 
Published: July 2019

Abstract
Over the past few years, research carried out at large-scale materials science facilities in the USA and elsewhere has undergone a phase transition that affected its character and culture. Research cultures at these facilities now resemble ecosystems, comprising of complex and evolving interactions between individuals, institutions, and the overall research environment. The outcome of this phase transition, which has been gradual and building since the 1980s, is known as the New (or Ecologic) Big Science [Crease, R. and Westfall, C. (2016). The new big science. Physics Today, 69: 30–6]. In this article, we describe this phase transition, review the practical challenges that it poses for historians, review some potential digital tools that might respond to these challenges, and then assess the theoretical implications posed by “database history’.