bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adoptive transfer of CTLA4-Ig-modulated dendritic cells improves TNBS-induced colitis
Authors: Paiatto Lisiery Negrini , Silva Fernanda Guimarães Drummond , Yamada Áureo Tatsumi , Tamashiro Wirla Maria Silva Cunha , Simioni Patricia Ucelli 
Published: June 2019

AbstractDendritic cells (DCs) play a crucial role in balancing immune responses, and in that sense the interactions between the B7-1 and B7-2 molecules expressed on DCs and CD28 and CTLA-4 on helper T cells are fundamental. While coupling of B7 and CD28 molecules activates immune responses, binding of B7 to CTLA4 results in its blockade. CTLA4-Ig fusion protein, a competitor molecule of the B7-CD28 interaction, has been used for the development of immunological tolerance both experimentally and in patients. Here, we evaluated the effects of adoptive transfer of bone marrow-derived dendritic cells (BMDCs) pulsed with CTLA4-Ig in TNBS-induced colitis. CTLA4-Ig-modulated BMDCs or naïve BMDC were administered intravenously to BALB/c mice prior to TNBS rectal instillation. Five days later, spleens and colon segments were removed for immunological and histological analysis. Our results showed that the adoptive transfer of CTLA4-Ig-modulated BMDCs was able to reduce the severity of inflammation caused by the administration of TNBS, in view of tissue integrity and reduced leukocyte infiltration in the colon segments of the treated mice compared to controls. Non-specific spleen cell activation in vitro showed a reduction in the frequency of CD4+IL-17+T cells and CD4+IFN-γ+T cells as well as IL-9 secretion in cultures. To our knowledge, this is the first description of the beneficial effects of treatment with CTLA4-Ig modulated BMDC in experimental colitis.
Precise on-line non-target pose measurement for cylindrical components based on laser scanning
Authors: Zhang Jieyu , Qiu Yuanying , Duan Xuechao , Yang Changqi 
Published: June 2019

Purpose
Cylindrical components are common in industry assembly areas. It is necessary to obtain their precise positions and orientations for their assemblies. But some measurement approaches relying on measuring targets are not allowed, as they may not meet the efficiency requirement of on-line measurement or may cause surface damages to the components. Thus, this paper aims to provide a precise on-line non-target scanning method based on 3D vision.

Design/methodology/approach
First, a laser profile sensor is used to acquire point cloud of the side surface of the measured cylindrical component. Then a composite process is conducted to estimate the pose and position of the axis. Aiming at this purpose, two fitting approaches, i.e., axis fitting and generatrix fitting, are tried respectively to estimate the pose parameters from the point cloud.

Findings
The results of Monte Carlo simulations demonstrate that neither the axis fitting nor the generatrix fitting could solely obtain the needed accuracy and precisions roundly. Thus, a new synthesis method is presented. And the results of prototype experiments validate the excellent accuracy and precision of the synthesis method.

Originality/value
This proposed new synthesis method combines the advantages of both the above fitting methods and can be easily integrated into the assembly line to guide the automation assembly process of the cylindrical components precisely.
Numerical and experimental investigation of bulk stress distribution in edge under different clamping sequence
Authors: Wang Hua , Wang Hailong 
Published: June 2019

Purpose
The edge is a typical aero-structural compliant part, whose length-width ratio is about 60:1 and height-thickness ratio is about 30:1. Distortion of the edge is mainly caused by the bulk stresses which come from the manufacturing process of the plates. This paper aims to investigate the effect of clamping sequence on the bulk stress distribution in the edge.

Design/methodology/approach
The paper conducts the numerical and experimental investigations to predict the bulk stress distribution in the edge under different clamping sequences. A finite element model of the plate with residual stress after quenching and stretching is constructed. The edge is milled from the plate numerically and is ready for clamping. The contact model between the clamper and the edge is constructed to simulate the clamping process. Then the edge is virtually clamped in different clamping sequences, and different deformations and bulk stresses are obtained. An experimental edge milled from the plate and a designed clamping platform are used to precisely control clamping force to verify the effect of clamping sequence on the bulk stress distribution in the edge. The experimental edge’s distortions, relative displacements between the edge and the clamper and clamping forces validate the proposed numerical model.

Findings
The primary cause of bulk stress redistribution is the friction between the rigid clamper and the compliant edge. The edge exhibits different deformation under different clamping sequences because of its compliant characteristics.

Originality/value
The proposed numerical model of the edge could predict the bulk stress distribution in the edge under different clamping sequence. The developed clamping platform could be used to conduct clamping experiments, including experiments with different clamping forces, sequences and different clamping positions. It will help to systematically improve the compliant assembling efficiency in civil aircraft industry.
Changing management strategies of a government-hosted festival
Authors: Cho B. Shine , Lee Juye , Lee Wonkang , Min Hyosang 
Published: June 2019

PurposeThe purpose of this paper is to examine the management strategy changes of a government-hosted festival from the government’s perspective based on Ansell and Gash’s (2008) definitive criteria of collaborative governance.Design/methodology/approachThis is a longitudinal case study of Hi Seoul Festival (HSF) in South Korea from 2003 to 2013. First, a detailed description of HSF management strategy change over time is presented through an analysis of internal government documents. Then, factors influencing management strategy changes are investigated through interviews with governmental and professional stakeholders.FindingsThe content analysis of the internal government documents reveals that HSF’s management strategy changed between collaborative governance and contracting out multiple times. The follow-up interviews then found that the prehistory experiences in managing festivals, the change of festival goals, and political leverages influenced the management strategy changes.Originality/valueThe government is one of the key stakeholders of festivals, which sometimes hosts and manages its own festivals. However, how a government manages its own festival is rarely studied. This study would add new insights into the studies of government-hosted festivals.
How do we start? An approach to learning analytics adoption in higher education
Authors: Gasevic Dragan , Tsai Yi-Shan , Dawson Shane , Pardo Abelardo 
Published: June 2019

Purpose
The analysis of data collected from user interactions with educational and information technology has attracted much attention as a promising approach to advancing our understanding of the learning process. This promise motivated the emergence of the field of learning analytics and supported the education sector in moving toward data-informed strategic decision making. Yet, progress to date in embedding such data-informed processes has been limited. The purpose of this paper is to address a commonly posed question asked by educators, managers, administrators and researchers seeking to implement learning analytics – how do we start institutional adoption of learning analytics?

Design/methodology/approach
A narrative review is performed to synthesize the existing literature on learning analytics adoption in higher education. The synthesis is based on the established models for the adoption of business analytics and finding two projects performed in Australia and Europe to develop and evaluate approaches to adoption of learning analytics in higher education.

Findings
The paper first defines learning analytics and touches on lessons learned from some well-known case studies. The paper then reviews the current state of institutional adoption of learning analytics by examining evidence produced in several studies conducted worldwide. The paper next outlines an approach to learning analytics adoption that could aid system-wide institutional transformation. The approach also highlights critical challenges that require close attention in order for learning analytics to make a long-term impact on research and practice of learning and teaching.

Originality/value
The paper proposed approach that can be used by senior leaders, practitioners and researchers interested in adoption of learning analytics in higher education. The proposed approach highlights the importance of the socio-technical nature of learning analytics and complexities pertinent to innovation adoption in higher education institutions.
Learning formative assessment in the field
Authors: Gao Su , Liu Katrina , McKinney Marilyn 
Published: June 2019

PurposeIt is suggested that mentor teachers engage in reflective conversations with preservice teachers to develop formative assessment as a teaching skill. However, there is minimal evidence documenting this process. The purpose of this paper is to investigate the process and impact of reflective conversation on preservice teachers’ learning about implementing formative assessment in the classroom.Design/methodology/approachThis study draws on two dyads of mentor and preservice teachers to examine the role of conversation in helping preservice teachers learn to use formative assessment in elementary classrooms in the USA. A comparative case study method is used to analyze and synthesize the similarities, differences and patterns across both cases.FindingsQualitative data indicate that reflective conversations enable preservice teachers to reflect on their teaching practices and learn how to conduct formative assessment. However, a lack of critical reflection in the conversations results in generic solutions that do not focus on specific aspects of student learning.Practical implicationsThis study suggests that mentor teachers using reflective conversation to guide preservice teacher’s critical analysis of their prior assumptions and teaching practices while referencing actual student learning is an essential element in learning to use formative assessment in the classroom.Originality/valueThis study contributes to the line of research that explores conversation between mentor and preservice teachers and provides an empirical analysis of conversations focused on learning to use formative assessment in elementary classrooms.
Human brain and financial behavior: a neurofinance perspective
Authors: Srivastava Mrinalini , Sharma Gagan Deep , Srivastava Achal Kumar 
Published: June 2019

PurposeThis study aims to review the relationship between neurological processes and financial behavior from an interdisciplinary perspective. Individual decision-making is influenced by cognitive and affective biases; hence, it becomes pertinent to understand the origin of these biases. Neurofinance is an emerging field of finance budding from neuroeconomics and explains the relationship between human brain activity and financial behavior, drawn from interdisciplinary fields, including neurology, psychology and finance.Design/methodology/approachThis conceptual paper extensively reviews the extant literature and performs meta-analysis to attain its research objectives.FindingsThe paper highlights the use of neuroimaging techniques in mapping the brain areas to help understand the processes in the higher cognitive areas of brain. The paper raises some new questions regarding individual preferences and choices while making financial or non-financial decisions.Originality/valueThe special focus on dysfunctions arising in brain because of injury and their impact on decision-making is also a key point in this paper and is summarized using meta-analytic forest plot. The existing literature provides instances where emotional processing is altered by injury in brain and may lead to more advantageous decisions, especially in risky situations.
Policy implementation deficiencies: Ghana’s microfinance sector failures
Authors: Quao Kwami Hope 
Published: June 2019

Purpose
Regulations to promote sanity in microfinance institutions and improve their operational problems yielded some results but lacked equal voice for effective implementation for its full realization. Much therefore has not changed in sub-Sahara African countries, though various types of regulation for microfinance exist. The nature and implementation of such policies therefore matter more than their mere presence. This paper aims to evaluate the nature of microfinance financial policies, given their social nature and the dynamism of their operational environment, and explores factors mitigating effective implementation of microfinance policy in Ghana.

Design/methodology/approach
A structured questionnaire was used to obtain data from the management and other officials of 63 microfinance institutions, and the outcome was organized into graphs and tables for descriptive analysis.

Findings
The results identified adequate adapted prudential regulation for microfinance institutions, but the formulation process lacked user input and adequate supervision, hindering effective sector policy implementation. The author therefore recommends a more inclusive and participatory policy formulation approach, creation of information platform for complete microfinance data through semi-autonomous supervisory body for microfinance services and regular full stakeholder engagement.

Research limitations/implications
Though the study is limited to tier-two microfinance institutions in Accra, it is evident that the results can be applied to the entire sector and across national borders because microfinance institutions exhibit similar or same characteristics.

Originality/value
This paper has not been submitted to or published by any other journal. The author certifies that the content of this paper is the product of his own work, and that other sources used in preparing this paper and their respective sources have been duly acknowledged.
Ownership structure and audit committee effectiveness: evidence from top GCC capitalized firms
Authors: Al-Musali Mahfoudh Abdulkarem , Qeshta Mohammed Helmi , Al-Attafi Mohamed Ali , Al-Ebel Abood Mohammad 
Published: June 2019

PurposeThe purpose of this study is to report on the level of audit committee (AC) effectiveness on the top capitalized firms in GCC countries and to empirically investigate the hypothesized influence of ownership types on the level of AC effectiveness.Design/methodology/approachThe empirical data were drawn from annual reports of 119 top listed firms in Gulf Co-operation Council (GCC) nations at the end of 2011. Ordinary least squares regression analysis was constructed to examine the relationships between ownership types and the level of AC effectiveness.FindingsThe findings revealed that family, government and institutional ownership, in addition to board independence, all have significant positive association with AC effectiveness, and they serve as a complement to AC effectiveness.Research limitations/implicationsThe findings of the study are important for policy makers and regulators as they could use them to understand the relationship between different corporate governance mechanisms and formulating best strategies that would help them to improve and adopt an optimal governance system constituted from interacting governance mechanisms.Originality/valueThis study is one of few that have examined the interaction between different corporate governance mechanisms. It provides insights about the relationship between AC effectiveness and other governance mechanisms in the GCC context.
Does non-profit brand image mean the same across cultures? An exploratory evaluation of non-profit brand image in three countries
Authors: Michaelidou Nina , Micevski Milena , Kadic-Maglajlic Selma , Budhathoki Tribikram , Sarkar Siddhartha 
Published: June 2019

Purpose
The current challenges international charities face with regards to their deteriorating image, as a result of recent scandals (e.g. Oxfam, Save the Children), provide the impetus for this exploratory research, where the purpose of this paper is to examine the conceptualization and dimensionality of non-profit brand image across national cultures.

Design/methodology/approach
The study employs a quantitative research design, using multi-country samples from India, Bosnia and Herzegovina and the UK. The authors first examine the psychometric properties of the non-profit brand image scale via confirmatory factor analysis across countries, identifying the optimal model for invariance testing. Further, the authors use multi-group invariance analysis to evaluate whether non-profit brand image (using an 18-item scale and six factors) provides equivalent measurement across cultures.

Findings
The study shows that individuals in the three countries perceive non-profit brand image equally, and as consisting of perceptions of usefulness, efficiency, affect, dynamism, reliability and ethicality. However, the results also indicate that the means of the dimensions of non-profit brand image are not comparable across different cultures.

Originality/value
The study extends limited current literature on non-profit brand image in international contexts, deriving insightful suggestions for further theoretical approaches in this under-developed research domain. It also yields key implications for charities and other non-profit organizations operating internationally, as they can use non-profit brand image and its dimensions as actionable tools in their communication campaigns to shape their brand image.
Identification and analysis of major risk factors causing national terrorism
Authors: Novikov Andrey Vadimovich , Koshkin Andrey Petrovich 
Published: June 2019

Purpose
National terrorism is a comprehensive problem caused by various factors and conditions that give rise to or are capable of giving rise to it. The paper aims to discuss this issue.

Design/methodology/approach
The purpose of this study is to identify the main risk factors contributing to the emergence of terrorism, based on an expert survey of the academic community and law enforcement officers who are directly involved in the security sector in the Russian regions.

Findings
The study identified 72 causes of national terrorism, which were then transformed into a questionnaire. The findings helped identify 18 major risk factors associated with the emergence of terrorism.

Originality/value
It was concluded that the elimination of these risk factors would generally reduce the impact of more insignificant factors. The results of the study may be useful for countries and national regions exposed to a high level of terrorist activity.
Impacts of mate attraction goal on young women’s interests in conspicuous consumption
Authors: Yuan Shaofeng , Zheng Yuhuang 
Published: June 2019

Purpose
Drawing on an evolutionary perspective, prior studies have revealed that conspicuous consumption by men has signaling functions (i.e. signaling the consumer’s positive mate qualities such as status and ability to acquire resources) for mate attraction. However, it is unclear whether conspicuous consumption of luxury products by women has a function in mate attraction. The purpose of this paper is to investigate the effect of mate attraction goal on women’s interest in conspicuous consumption and the possible mediating effect of the attractiveness enhancement need in this effect.

Design/methodology/approach
A survey and two experimental studies were conducted in which 354 Chinese female undergraduates participated. In the survey, the respondents’ desire to have a romantic partner was measured; in the two experiments, the participants’ mate attraction goals were primed. The authors followed the literature to measure dependent variables (i.e. consumption measures), but the specific consumption items were adapted to meet the purpose of the current research. The authors analyzed the data from the three studies through analysis of variance, regression analysis and bootstrapping.

Findings
Young women with a strong (vs weak) desire for a romantic partner reported a high level of attractiveness enhancement needs, thereby indicating a higher willingness to pay (WTP ) for conspicuous items that can enhance their attractiveness (Studies 1 and 3). Furthermore, activating young women’s mate attraction goal can also increase their WTP for conspicuous items (Studies 2 and 3) and attractiveness enhancement items (Study 3) but not inconspicuous luxury product (e.g. underclothes) (Study 3). These findings suggested that young women consider conspicuous consumption of certain products as a means of enhancing attractiveness to acquire a desired mate.

Originality/value
This research identifies a novel function of conspicuous consumption: young women, especially those who do not have a romantic partner, may use conspicuous consumption of certain products to satisfy their attractiveness enhancement needs and, ultimately, to attract an ideal mate.
Face consciousness and conspicuous luxury consumption in China
Authors: Zhang Xin-an , Wang Wangshuai 
Published: June 2019

Purpose
Luxury consumption in China is featured by clear conspicuous purposes. The purpose of this paper is to investigate this phenomenon from the indigenous perspective of face consciousness.

Design/methodology/approach
Drawing on Ho’s (1976) framework of gaining vs losing face process, the authors decomposed the construct of face consciousness into two dimensions, namely, desire to gain face and fear of losing face, and developed a multi-dimensional scale for face consciousness. Then, a survey that consisted of 338 participants was conducted to test the relationship between face consciousness and luxury consumption.

Findings
The face consciousness scale was shown to be reliable and valid. Furthermore, the authors found both desire to gain face and fear of losing face had a unique contribution in explaining why Chinese consumers purchase luxury products.

Originality/value
This paper fills the gap in the extant literature by developing a multi-dimensional face consciousness scale, providing convenience for empirical research in future. Moreover, this research shows that Chinese consumers’ luxury consumption behavior contains both promotion and prevention motivation.