bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estado social e identidad europea
Authors: Ballesteros Panizo Covadonga Isabel 
Published: March 2019

El estudio presenta el modelo de Estado social como un distintivo de la identidad de Europa. Para ello se analizan los orígenes del Estado social, los valores sobre los que se sostiene, así como los cambios que en la actualidad este modelo está sufriendo. La relevancia del tema objeto de estudio se encuentra en la aparente amenaza que para la identidad europea podría plantear la tendencia privatizadora de los servicios esenciales. Para ello el trabajo aborda el estudio de las actuales relaciones entre Estado y sociedad. Hace apenas unas décadas en el modelo de Estado social el Estado aparecía como único prestador de los servicios esenciales para la comunidad; hoy, sin embargo, el Estado aparece como garante de esos servicios, que prestan y cuya titularidad ostentan los operadores privados. Se advierte, en este sentido, que la tendencia liberalizadora no es necesariamente contraria al Estado Social, siempre y cuando se articule una adecuada regulación que garantice sus principios. Como conclusión del trabajo destaca la necesidad de que Europa proteja los valores sobre los que se sustenta el modelo de Estado de los países que la integran, para así preservar su genuina identidad.Recibido: 02 julio 2018 Aceptado: 10 septiembre 2018 Publicación en línea: 27 febrero 2019
Rethinking Cosmopolitanism: Political and Metapolitical Identities
Authors: Torres Bernat , Monserrat Molas Josep 
Published: March 2019

The paper defends the notion that cosmopolitanism is an important starting point for addressing political identities, but one that needs to be rethought. The paper starts by exposing some political situations both in Europe and in North America where the debate on national identity is faced with the need for a renewed idea of cosmopolitanism, an idea that must be differentiated from similar notions such as cultural diversity or multiculturalism, but also from the idea of globalization. It shows in this sense that there is an important and often forgotten difference between cosmopolitanism and politics, an essential difference when thinking about the real situation in Europe. The paper explains how contemporary cosmopolitanism has its roots in the Stoic and Kantian ideals, ideals that are no longer serviceable and that need to be renewed to confront the new demands of the complexity of the world. The paper concludes defending a new cosmopolitanism (tending towards the line of Hans Jonas or Yves Charles Zarka) that should be respectful to politics (but without forgetting that cosmopolitanism should be prioritised over politics) and also with different national or supranational identities, since it in fact provides a meta-identity for man as a citizen of the world. Received: 02 July 2018 Accepted: 16 July 2018 Published online: 27 February 2019
Europa desde la frontera: el final del Socialismo en los Balcanes (1980-1990)
Authors: Baró i Queralt Xavier 
Published: March 2019

En un congreso centrado en la reflexión sobre la identidad europea, parece pertinente preguntarse sobre los límites geográficos y culturales de Europa. En este sentido, los Balcanes, verdadera encrucijada entre Occidente y Oriente, suponen un privilegiado campo de estudio para conocer la otra Europa. Centrados en los Balcanes, en esta comunicación se analizará el complejo sustrato identitario de la región, marcado, entre otros, por la propia diversidad cultural y religiosa, en la que conviven las religiones cristiana (ortodoxos y católicos) y musulmana. Para nuestros textos hemos fijado las cesuras cronólogicas de 1980 (año de la muerte de Josip Briz, Tito, fundador de la Yugoslavia contemporánea y máximo representante del «socialismo autogestionario») y 1990 (año en que se derrumban la mayoría de regímenes socialistas de los Balcanes). Se prestará especial atención a la relación entre los acontecimientos históricos y su influencia en los rasgos identitarios de una macroregión fronteriza de Europa, así como a la compleja relación entre nacionalidades y estados limítrofes.Recibido: 02 julio 2018 Aceptado: 16 julio 2018 Publicación en línea: 27 febrero 2019
Pembacaan Kontekstual Fazlur Rahman Atas Sunah Dan Hadis (Upaya Mendialektikkan Dua Tipologi Pemikiran Tradisionalis Dan Modernis)
Authors: Roibin Roibin 
Published: March 2019

Fazlur Rahman states that Sunnah tends to be guidance not a set of rule. Thus, efforts should be done to formalize, verbalize and make it permanent in the form of Hadith text. Otherwise, Moslems will face discontinuity of history. However, the formulized Hadiths do not necessarily mean that the Hadiths become absolute. When it is so, the Hadiths were essentially reduced.
Model Analisis Sistem Pengolahan Limbah lndustri Tekstil Menggunakan Bioflokulan Moringa Oleifera Lam.
Authors: Sukarsono Sukarsono 
Published: March 2019

Waste water from textile factories classified into dangerous water as regulated by the Ministry of Environment. This waste water usually flows away into the river environment around of factories. Water treatment unit of textile factory believed as an external unit process which need big budget consequences because it might use imported chemical substances. This situation usually use as a common reasons to pollute the environment. This research is a model solution to reduce a fix budget (cost production) in textile production by using a number of Moringa oleifera as a biofloculant to replace an expensive chemical substances as PAC. This model showed the number of biofloculant at every target number of production and the impact into amount of sludge and water. Linear model commonly found in every stage of simulation. This research showed what kind of preparation needed by environmental factory manager.
The prevalence of sleep breathing disorders in patients with atrial fibrillation undergoing catheter treatment
Authors: Agaltsov M. V. , Drapkina O. M. , Davtyan K. V. , Arutyunyan G. G. 
Published: March 2019

Aim. To study the prevalence of obstructive sleep apnea (OSA) among patients with atrial fibrillation (AF) who have undergone catheter treatment for this arrhythmia, as well as to study the possible interrelationships of these sleep breathing disorders with comorbid diseases and the received therapy in this cohort.Material and methods. 231 patients from a random sample were examined (men – 118 [51.1%], mean age 57.8±9.3 years) in the range of 1-6 months after catheter therapy for AF. All patients underwent cardiorespiratory sleep monitoring for one night. The criterion for OSA severity was apnea/hypopnea index (AHI) for hour (the norm is less than 5 events/h). Depending on the results obtained, all patients were divided into groups without apnea and with apnea of varying severity – a mild degree with an AHI value of 5 to 15 events/h, moderate severity with an AHI value of 16 to 30 events/h, and severe degree when the value of AHI more than 30 events/h. The study was performed without abolishing the basic therapy.Results. According to the results of cardiorespiratory sleep monitoring 127 patients (56.7%) with OSA criteria, were registered. Among them, a mild degree of OSA was found in 35.4% (n=45), a moderate degree – in 40.9% (n=52), and severe one – in 23.7% (n=30) of all patients with apnea. Among patients with obstructive sleep apnea 51.1% were males. Arterial hypertension was significantly more frequent in patients with OSA of pronounced degrees of severity compared with patients without apnea (p=0.047). Weight and body mass index of patients with OSA were significantly higher than in patients without apnea (p=0.001 and p=0.001, respectively). The left atrium (LA) size in patients with severe OSA was significantly larger than in patients without apnea (p=0.0005), which may indicate a possible contribution of severe obstructive apnea to the arrhythmia generating. OSA was the strongest independent factor among others related to the LA size (odds ratio was 1.6; 95% confidence interval 1.2-2.1; p<0.0003).Conclusion. Obstructive sleep apnea is very widespread among a cohort of patients with AF who have undergone a catheter procedure to isolate the pulmonary veins. Sleep breathing disorder is the strongest and most independent risk factor for AF associated with increased LA, among other risk factors such as age, hypertension, and obesity.
Factors Associated with Cause-Specific Death in Russia. Data from Longitudinal Prospective Study 1977-2001
Authors: Shalnova S. A. , Kapustina A. V. , Deev A. D. , Balanova Yu. A. 
Published: March 2019

Aim.To evaluate the associations between main risk factors (RF) with cause-specific death in cohorts of Russian men and women.Material and methods. Data of a number of crossectional studies conducted in different years by unified base protocol had become the subjects for the study. A total of 12,497 men and 5,039 women aged 35-74 years, residents of Moscow and S-Petersburg (former Leningrad) cities at the moment of examination, were enrolled into the study. We analyzed 17 previously selected risk factors and their associations with cause-specific mortalities: coronary heart disease (CHD), stroke, cardiovascular diseases (CVD), non-CVD, all causes. A total of 10,650 deaths were registered: 8,726 in men (for 10 years) and 1,924 – in women (for 20 years).Results.Men died more often from all the examined causes except for stroke, what was more typical to women. Mortality in men was associated with significantly larger number of RF than in women and correlations were stronger. In particular, smoking (hazard ratio [HR] 2.25; 95% confidence interval [95%CI] 1.75-2.89; р=0.0001), high blood pressure (HR 1.78; 95%CI 1.43-2.22; р=0.0001) and history of CHD (HR 3.23; 95%CI 2.71- 3.84; р=0.0001) significantly increased CHD-related mortality in the men’s cohort but were much less significant for women. The total cholesterol level demonstrated significance in men but was not even selected in the model for women. The main RF for stroke-related mortality were smoking, high blood pressure and atrial fibrillation, while for non-cardiovascular mortality there was only one common factor – smoking. Factors associated with CVD and all-cause mortality were almost the same because CVD cover more than half in the all-cause mortality, however a larger number of predictors were reported in men.Conclusion. The data obtained indicate: 1) considerably larger number of unfavorable risk factors in the men’s cohort, which significantly increased risk for death from any cause; 2) statistically more pronounced relation between risk factors and mortality rates in men as compared to women, especially note that mortality rates were followed up for 10 years in men and 20 years in women. It is obvious that successful prevention focused on risk factors must be gender-based.
Assessment of Antithrombotic Therapy in Patients with Atrial Fibrillation for 2015-2017 According to the Registry of the Clinic of the Scientific Research Institute of Medical Problems of the North of Krasnoyarsk City
Authors: Tuchkov A. A. , Gogolashvili N. G. , Yaskevich R. A. 
Published: March 2019

Aim. To evaluate the volume of antithrombotic therapy (ATT) at the prehospital stage in connection with the risk of thromboembolic complications, and also to study the dynamics of the frequency of administration of oral anticoagulants (ОAC) in patients with atrial fibrillation (AF) in 2015-2017.Material and methods. The registry included 562 patients with AF at the age of 18 years and older, hospitalized in the cardiology department during 2015-2017. The registry did not include patients with AF and mechanical heart valves, mitral stenosis. The diagnosis of AF was established in accordance with the current recommendations. All patients had an assessment of the risk of thromboembolic complications on the CHA2DS2-VASc scale, the risk of bleeding on the HAS-BLED scale. The incidence of ATT at the prehospital stage was assessed depending on the risk of thromboembolic complications based on patient questioning and analysis of medical records. In addition, an assessment of the dynamics of the frequency of the OAC prescription during 2015-2017 was conducted.Results. The overwhelming majority of patients with AF (96.1%) belonged to the group of high-risk of cardioembolic strokes according to the CHA2DS2-VASc scale and had indications for OAC therapy. The frequency of OAC prescription in patients with AF who were admitted to the cardiology department was 32% at the prehospital stage, of which 19.8% of patients took warfarin and 12.2% – direct OAC. The target level of the international normalized ratio (from 2.0 to 3.0) at the time of hospitalization was observed only in 33.6% of patients taking warfarin. Over the observation period, there was a tendency to increase the frequency of OAC prescription from 30% in 2015 to 38.4% in 2017.Conclusion. Only 32% of patients with AF and high risk of thromboembolic complications received adequate antithrombotic therapy at the prehospital stage. According to the registry the frequency of OAC prescription in patients with AF during 2015-2017 increased by 8.4%. At the same time, there was a significant increase in the frequency of direct OAC prescription.
Prognostic Value of ECG in Patients with Pulmonary Embolism
Authors: Mullova I. S. , Pavlova T. V. , Khokhlunov S. M. , Duplyakov D. V. 
Published: March 2019

Aim. To study the significance of electrocardiography (ECG) signs for determining the hospital prognosis in patients with pulmonary embolism (PE).Material and methods. 472 consecutive patients (49.6% men; average age 58.06±14.28 years) with PE, hospitalized to our center from 23.04.2003 to 18.09.2014 were enrolled into the study. In all cases PE was confirmed by computed tomographic pulmonary angiography and rarely by pulmonary angiography, or by pathology. Patients management was in accordance with appropriate European guidelines. Data of patients' history, clinical symptoms, biochemical markers and instrumental methods (ECG, echocardiography) were analyzed by one-dimensional logistic regression. The end points were: death, shock and hypotension, right ventricular dysfunction and pulmonary hypertension, positive cardiac biomarkers.pulmonary embolism, electrocardiography, prognosis, collapse, hypotension, dysfunction of the right ventricle. 443 patients (93.9%) without fatal outcome were the first group and 29 patients (6.1%) with a fatal outcome – the second group. SIQIII pattern (33 vs 55.2%; p=0.015), non-complete right bundle branch block (RBBB) (16.3 vs 37.9%; p=0.001), ST segment elevation in lead III (9.7 vs 20.7%, p=0.034), atrial fibrillation (12.9 vs 37.9%, p=0.048) were observed more frequently among patients of group 2. Multivariate analysis revealed that SIQIII pattern (odds ratio [OR] 2.26; 95% confidence interval [95%CI] 1.046-4.868; p=0.038) and RBBB (OR 2.84; 95%CI 1.272-6.327; p=0.011) were associated with worse prognosis. The SIQIII pattern was significantly associated with a fatal outcome with a sensitivity of 55% and a specificity of 33% (AUC=0.611) according to ROC-analysis. Risk of hypotension was related to the following ECG-signs: the p-pulmonale (OR 1.76; 95%CI 1.001-3.088; p=0.049), negative T-wave in lead III (OR 1.8; 95%CI 1.035-3.144; p=0.037). Inversion of the T wave in lead III was associated with the development of shock (OR 1.98; 95%CI 0.891-4.430; p=0.043).ECG-signs were also associated with the development of right ventricular dysfunction and pulmonary hypertension: right axis deviation (OR 1.035; 95%CI 1.008-1.062; p=0.01), ST-segment elevation in the AVR lead (OR 3.769; 95%CI 1.018-13.955; p=0.047), negative T wave in leads III, V1-V3 (OR 1.015; 95%CI 1.008-1.023; p=0.001 and OR 1.014; 95%CI 1.005-1.022; p=0.001, respectively), RBBB (OR 1.013; 95%CI 1.003- 1.024; p=0.012), p-pulmonale (OR 1.015; 95%CI 1.007-1.023; p=0.001), deep S in leads V5-V6 (OR 1.015; 95%CI 1.006-1.024; p=0.001). However, there was no significant relationship between ECG signs and cardiac biomarkers (troponin I and BNP).Conclusions. SIQIII pattern, RBBB and inversion of the T wave in lead III have prognostic value in unselected population of patients with PE.
Informasi, Literasi Media dan Pustakawan
Authors: Hapsari Dian 
Published: March 2019

Media dan manusia merupakan hal yang saling berkaitan. Disadari atau tidak media banyak mempengaruhi pola hidup manusia. Perkembangan media ditambah dengan teknologi menghasilkan jumlah informasi yang semakin meningkat. Banjir Informasi menjadi masalah baru yang dihadapi saat ini sehingga perlu dilakukan kesadaran media yang salah satu nya melalui literasi media. Pustakawan di perguruan tinggi. dapat terlibat dalam kegiatan literasi media untuk mendukung proses pembelajaran melalui kegiatan seperti: workshop, seminar, leaflet serta memberi pengumuman dengan menggunakan fasilitas web perpustakaan. Selain itu perpustakaan juga dapat berkolaborasi dengan institusi lain dalam kegiatan literasi media. Agar dapat melakukan literasi media yang baik, pustakawan perlu ditunjang kompetensi yang memadai untuk melakukan hal tersebut. Diharapkan dengan dapat terlaksananya literasi media oleh pustakawan perguruan tinggi, tingkat kesadaran media civitas academika akan semakin meningkat. Dengan demikian budaya literasi dapat terwujud dengan baik, karena pada dasarnya literasi merupakan soft skill yang harus dimiliki oleh manusia untuk bertahan hidup
Preparation of low-cost sludge-based mesoporous carbon and its adsorption of tetracycline antibiotics
Authors: Junyu Zou , Zefeng Song , Yuesuo Yang 
Published: March 2019

Abstract
Preparation of sludge-derived mesoporous carbon materials (SMCs) through pyrolysis of excess activated sludge from urban municipal sewage plants is an effective means of reducing pollution and utilizing a waste resource. This paper presented a method of SMC preparation in which calcium oxide (CaO), polyacrylamide (PAM), and chitosan (CAS) flocculating agents were used as pore-forming additives. Physical and chemical characterizations of the prepared SMCs were conducted by scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET), Fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy (XPS). The prepared SMCs were used to adsorb a tetracycline (TC) antibiotic pollutant. The influences of pH, adsorption time, temperature, and pollutant concentration on TC adsorption capacity were determined. The experiments demonstrated that weakly acidic conditions were conducive to TC adsorption, which mainly occurs via electrostatic and π-π interactions. The TC adsorption process by SMCs conformed better to the pseudo-second-order models, indicating that chemical adsorption was the dominant adsorption process. The isothermal adsorption of TC by the SMCs conformed to the Freundlich model. This implied that TC easily adhered onto the SMC surfaces via multilayer homogeneous adsorption. Thermodynamic studies revealed that the adsorption of TC onto SMCs was spontaneous and endothermic.
Repurposing Glyburide as Antileishmanial Agent to Fight Against Leishmaniasis
Authors: Rub Abdur , Shaker Kamal , Kashif Mohammad , Arish Mohd , Dukhyil Abdul Aziz Bin , Alshehri Bader Mohammed , Alaidarous Mohammed A. , Banawas Saeed , Amir Khwaja 
Published: March 2019

Background:Leishmaniasis is caused by a protozoan parasite, Leishmania. It is common in more than 98 countries throughout the world. Due to insufficient availability of antileishmanial chemotherapeutics, it is an urgent need to search for new molecules which have better efficacy, low toxicity and are available at low cost.Objectives:There is a high rate of diabetic cases throughout the world that is why we planned to test the antileishmanial activity of glyburide, an effective sugar lowering drug used for the treatment of diabetes. In this study, glyburide showed a significant decrease in the parasite growth and survival in vitro in a dose-dependent manner.Methods:Anti-leishmanial activity of glyburide was checked by culturing Leishmania donovani promastigotes in the presence of glyburide in a dose and time dependent manner. Docking study against Leishmania donovani-Trypanothione synthetase (LdTrySyn) protein was performed using Autodock Vina tool.Results:Growth reversibility assay shows that growth of treated parasite was not reversed when transferred to fresh culture media after 7 days. Moreover, docking studies show efficient interactions of glyburide with key residues in the catalytic site of Leishmania donovani- Trypanothione synthetase (LdTrySyn), a very important leishmanial enzyme involved in parasite’s survival by detoxification of Nitric Oxide (NO) species, generated by the mammalian host as a defense molecule. Thus this study proves that the drug-repurposing is a beneficial strategy for identification of new and potent antileishmanial molecules.Conclusion:The results suggest that glyburide binds to LdTrySyn and inhibits its activity which further leads to the altered parasite morphology and inhibition of parasite growth. Glyburide may also be used in combination with other anti-leishmanial drugs to potentiate the response of the chemotherapy. Overall this study provides information about combination therapy as well as a single drug treatment for the infected patients suffering from diabetes. This study also provides raw information for further in vivo disease model studies to confirm the hypothesis.
The Application of Microfluidic Techniques on Tissue Engineering in Orthopaedics
Authors: Wang Lingtian , Jiang Dajun , Wang Qiyang , Wang Qing , Hu Haoran , Jia Weitao 
Published: March 2019

Background:
Tissue engineering (TE) is a promising solution for orthopaedic diseases such as bone or
cartilage defects and bone metastasis. Cell culture in vitro and scaffold fabrication are two main parts of TE, but
these two methods both have their own limitations. The static cell culture medium is unable to achieve multiple
cell incubation or offer an optimal microenvironment for cells, while regularly arranged structures are unavailable
in traditional cell-laden scaffolds, which results in low biocompatibility. To solve these problems, microfluidic
techniques are combined with TE. By providing 3-D networks and interstitial fluid flows, microfluidic platforms
manage to maintain phenotype and viability of osteocytic or chondrocytic cells, and the precise manipulation of
liquid, gel and air flows in microfluidic devices leads to the highly organized construction of scaffolds.

Methods:
In this review, we focus on the recent advances of microfluidic techniques applied in the field of tissue
engineering, especially in orthropaedics. An extensive literature search was done using PubMed. The introduction
describes the properties of microfluidics and how it exploits the advantages to the full in the aspects of TE. Then
we discuss the application of microfluidics on the cultivation of osteocytic cells and chondrocytes, and other
extended researches carried out on this platform. The following section focuses on the fabrication of highly organized
scaffolds and other biomaterials produced by microfluidic devices. Finally, the incubation and studying of
bone metastasis models in microfluidic platforms are discussed.

Conclusion:
The combination of microfluidics and tissue engineering shows great potentials in the osteocytic cell
culture and scaffold fabrication. Though there are several problems that still require further exploration, the future
of microfluidics in TE is promising.