bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Philosophical Mea Culpa of the Icons of the Death of the Author
Authors: Krasniqi Nysret 
Published: April 2019

[full article, abstract in English; abstract in Lithuanian]
We will hereinafter discuss the author’s philosophy on gnoseological and historical premises. More precisely, by exploring the genealogy of the idea of the “Death of the Author” from modernism to postmodernism, we will analyse the concepts and ideologies that have become the stratagem of the denial of western literary canon, as well as the denial of equilibrium between philosophical and literary identity and universality. By treating the works of philosophers, authors, and fundamental semiologists who perpetuated the idea of the Death of the Author, we will observe how the latter gradually fled from the philosophy of doubt and as mea culpa admitted that without the author’s authority the philosophical and literary legacy is no longer the theatre of memory, but the abyss of oblivion. Moreover, with fundamental examples, we will observe the influence of this philosophy in the process of studying of the literature.
Anti-Bacterial and Anti-Fungal Activities from Macaranga bancana Leaves Extract
Authors: Putri Rianti , Hendra Rudi , Teruna Hilwan Y. 
Published: April 2019

Macaranga bancana is one of the Indonesian medicinal plants that is empirically used to treat infectious disease. The aim of this study was to evaluate anti-bacterial and anti-fungal activities of M. bancana against human pathogenic microbes, i.e., Escherichia coli, Staphylacoccus aureus, and Candida albicans. The dried leaves of M. bancana were extracted using cold extraction method with n-hexane, dichloromethane, ethylacetate, methanol, and ethanol solvents. The evaluation of anti-microbial activity from these extracts at the concentration of 1000 µg/ml was conducted using microdilution method. Amoxicillin, cephadroxil, and ketoconazole were used as positive controls. All extracts showed 100% inhibitory activity against S. aureus, with the exception of ethanol extract which was 72.8%. Nevertheless, methanol and ethanol extracts showed 100% inhibitory activity against E. coli, while the lowest activity was shown by n-hexane extract ( 45.2%). All extracts exhibited 100% inhibitory activity against C. albicans. In conclusion, leaves extract of M. bancana is a potential source of anti-bacterial and anti-fungal agents. Keywords: anti-bacterial, anti-fungal, M. bancana, microdilution
Effect of Fermentation Time of Kombucha Tea on Its Hypoglycaemic Activity in Rats
Authors: Setiani Nur A. , Anggriani Rika L. , Restiasari Anggi 
Published: April 2019

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia. Functional food, such as kombucha tea, is widely used as complementary treatment for type 2 diabetes mellitus. Kombucha tea is made through fermentation process of green or black tea using a microbial kombucha consortium (Acetobacter xylinum and several types of yeast). The aim of this study was to evaluate the effect of fermentation time of kombucha tea on its hypoglycaemic activity in rats. The green tea (Camellia sinensis) was fermented with kombucha consortium for 8, 14, and 21 days. Evaluation of hypoglycaemic activity was conducted using glucose tolerance test method. First, fasting blood glucose levels in rats were measured after 16 hours fasting. Hyperglycaemic condition was induced by administering glucose 2 g/0.2 kg body weight. Blood glucose levels were measured again after 30 minutes. Subsequently, 5.5 ml of kombucha tea in various fermentation time was orally administered. Blood glucose levels were measured at 30, 60, 90, 120, 150 and 180 minutes after kombucha tea administration. The results revealed the average reduction of blood glucose were 18.16%, 33.64%, and 19.88% by kombucha tea fermented for 8, 14, and 21 days, respectively. In conclusion, kombucha tea fermented for 14 days is potential to be developed as a hypoglycaemic agent. Keywords: fermentation time, glucose level, hypoglycaemia, kombucha tea
In-Vivo Effectiveness of 5% Azadirachta indica Oil Cream as Anti-Scabies
Authors: Husni Patihul , Dewi Mayang K. , Putriana Norisca A. , Hendriani Rini 
Published: April 2019

Scabies is an infectious skin disease caused by mite Sarcoptes scabiei. Neem tree (Azadirachta indica) has the potential to be used as an anti-parasite due to the presence of azadirachtin compound that is commonly found in the seeds. The aim of this study was to evaluate in-vivo effectiveness of neem oil as an anti-scabies. This study used an experimental method. The effectiveness of the cream as an anti-scabies was tested on New Zealand white rabbits which were infected with scabies. Permethrin cream was used as a positive control and cream base was used as a negative control. Cream was applied once daily and left for 8 hours. The data were analyzed using Kruskal Wallis and Mann Whitney. Dermal acute irritation test was performed by applying 0.5 g cream on the rabbit dorsal. We found that 5% neem oil cream was effective as an anti-scabies with 20-21 days recovery time. The recovery time is longer than permethrin cream (7-8 days), but shorter compared to negative control with recovery time over 30 days. Primary irritation index for 5% neem oil creams was 0, indicating negligible irritation category. In conclusion, A. indica cream was effective for the treatment of scabies although its recovery time is shorter than permethrin cream. Keywords: effectiveness test, irritation test, neem oil cream, scabies
Anti-Inflammatory Activity of Artocarpus altilis (Parkinson) Fosberg in Wistar Male Rats
Authors: Riasari Hesti , Nurlalela Sani , Gumilang Ginanjar C. 
Published: April 2019

Inflammation is a local reaction in vascular tissue characterized by several symptoms, e.g., swelling, redness, and pain. Indonesia is one of the countries with high biodiversity, including traditional medicinal plants. Artocarpus altilis is one the plants that is widely used to treat inflammation. There is limited information on biological activity of A. altilis.This study was performed to evaluate anti-inflammatory properties of A. altilis detached and attached leaves in Wistar male rats. A. altilis was extracted using soxhlet method at 67.4 0C with methanol solvent. Inflammation was induced by the administration of carrageenan to the rats paw. Subsequently, the extract of A. altilis were orally administered. The edema were measured using plethysmometer for 6 hours. We found that there were differences in anti-inflammatory activity between detached and attached leaves. The inhibition of edema in attached leaves were 50% and 53.33% for the concentration of 50 mg and 100 mg, respectively. The greater inhibiton was observed in the detached leaves, with 73.33% and 76.67% inhibition, for the concentration of 50 mg and 100 mg, respectively. Nevertheless, the inhibition percentage was still below diclofenac sodium as a positive control (83.33%). In conclusion, A. altilis leaves extracts showed good anti-inflammatory properties and has the potential for development of anti-inflammatory drug. Keywords: Artocarpus altilis, carageenan, inflammation, edema
Four new combinations of the genera Bulbophyllum and Dendrobium (Orchidaceae) from the Philippines
Authors: Naive Mark Arcebal K. , Calaramo Michael A. , Alejandro Grecebio Jonathan 
Published: April 2019

Three new combinations under the genus Bulbophyllum and one new combination under the genus Dendrobium are proposed. This work is aimed to solve the ambiguity in the Philippine Orchidaceae.
Keywords: Epidendroideae, Malesian flora, Mindanao, plant taxonomy, tropical botany
20th Congress of Russian Society of Holter Monitoring and Noninvasive Electrophysiology (ROHMINE). 12th All-Russian Congress "Clinical Electrocardiology". 5th All-Russian Conference of FMBA pediatric cardiologists of Russia
Authors: Editorial Article 
Published: April 2019

20th Congress of Russian Society of Holter Monitoring and Noninvasive Electrophysiology (ROHMINE).12th All-Russian Congress "Clinical Electrocardiology".5th All-Russian Conference of FMBA pediatric cardiologists of Russia
Valved and Non-Valved Drainage Systems in the Surgical Treatment of Refractory Glaucoma
Authors: Karlova E. V. , Radaykina M. V. 
Published: April 2019

Purpose: to compare the efficacy and safety of Ahmed and Molteno-3 drainage devices implantation in the surgical treatment of refractory glaucoma. Patients and methods. Two groups of refractory glaucoma patients underwent surgery. In the first group (48 patients, 48 eyes) drainage device Molteno-3 with a site size of 175 mm2 was implanted. The average IOP in the group before surgery was 31.9 ± 7.7 mm Hg. The average number of glaucoma medications was 3.3 ± 0,44. In the second group (51 patients, 51 eyes) implantation of Ahmed Valve FP7 model was performed. The average level of IOP in the group before surgery was 34.7 ± 8.07 mm Hg. The average number of glaucoma medications was 3.08 ± 0.4. Results. In the first group the average intraocular pressure level 1 month post-op was 14.6 ± 6.1 mm Hg, 3 months post-op 18.8 ± 5.2 mm Hg, 6 months post-op 16.5 ± 4.7 mm Hg. IOP сompensation (≤ 21 mm Hg) in 6 months was achieved in 91.6 % of cases and in 1 year in 100 % of cases. The total success was achieved only in 8.3 % of patients. However, the number of glaucoma medications was reduced to 1.6 ± 0.8. In the second group the average IOP level 1 month post-op was 21.25 ± 7.3 mm Hg, 3 months post-op 17.9 ± 5.3 mm Hg, 6 months post-op 15.7 ± 4.1 mm Hg. IOP сompensation in 6 months was achieved in 82.4 % of cases and in 1 year in 86.3 %. In the second group complete success was achieved in 19.6 % of patients. The number of glaucoma medications was 1.4 ± 1.1. In the first group complications were revealed in 22.9 % of cases (11 patients). Ciliochoroid detachment was revealed in 9 patients (18,8 %) and hyphema in 2 patients (4,2 %). In the second group complications were revealed in 19.6 % of cases (10 patients). Сiliochoroid detachment was revealed in 4 patients (7.8 %), diplopia in 5 patients (9.8 %), hyphema was detected in one case (1.9 %). In the first group IOP compensation (≤21 mm Hg) was achieved after 6 months in 91.6 % of cases and after 1 year in 100 % of cases. The complete success was achieved in only 8.3 %. In the second group, IOP compensation in 6 months was achieved in 82.4 % of cases and 86.3 % — in 1 year. In the second group, complete success was achieved in 19.6 % patients. There was no significant difference in complications between two groups. Conclusion. High level of safety and effectiveness of refractory glaucoma surgical treatment with implantation of Molteno-3 and Ahmed drains was confirmed.
The First Experience of Using a Femtosecond Laser in Pterygium Surgery
Authors: Kazakbaev R. A. 
Published: April 2019

Objective: to evaluate the functional results of the surgical treatment of pterygium using a femtosecond laser. Рatients and methods. The study included 115 patients (141 eyes) with a diagnosis of primary and recurrent stage I–III pterygium, of which 17 (19 eyes, 10.6%) had a relapse of the disease. The patients’ age was in average 54 ± 6 years, among them men and women — 56 and 44 % respectively. The same surgeon operated all patients with a femtosecond laser and fibrin glue. Results. The technique is simple to perform, the separation of the autograft from its own conjunctiva does not cause difficulties due to an accurate cut of the femtosecond laser, which helps to obtain optimal functional results in the long-term period. The size of an autograft manufactured using a femtosecond laser averaged 6 × 7 ± 1.0 mm. The edges of the graft in all cases were smooth, its thickness was the same over the entire area and amounted to 80 ± 15 μm, which facilitated the work with it and subsequent fixation. The graft was fixed using fibrin glue, the advantage of which is its hypoallergenicity, the absence of discomfort in patients and the simplicity of its use by the surgeon. Glue resorption is completed from 2 weeks to 1 month. Intra and postoperative complications were not observed in any case. The offset of autograft in the early postoperative period was also not observed in any case. Conclusion. The use of a femtosecond laser in primary and recurrent pterygium I-III surgery allows the formation of an autograft of the required thickness and size with minimal damage to the conjunctival vessels and the absence of scarring of the bulbar conjunctiva in the area of the material intake. The use of fibrin glue for fixing the autograft promotes rapid healing. The absence of relapses during the observation period and obtaining optimal functional results indicate the promise of using femtolaser technologies in pterygium surgery.
Professor Victor P. Odintsov is the Founder and the First Director of Ufa Eye Research Institute Bashkir State University
Authors: Galimova Yu. Sh. 
Published: April 2019

Professor V. Odintsov is a surgeon, researcher, teacher and organizer who made an enormous contribution to the development of country and world ophthalmology. In 1925, V. Odintsov was invited to Ufa for the management of Eye Infirmary and became the founder of the Bashkir Trachomatous Research Institute which was the centre of elimination trachoma in the republic. The development of the ophthalmology in the republic of Bashkortostan is connected with his name.
Maculopathy Development Mechanism in Choroid Tumor Localization Outside the Foveolar Zone
Authors: Brovkina A. F. , Stoyukhina A. S. , Budzinskaya M. V. , Musatkina I. V. 
Published: April 2019

The term “distant maculopathy” (DM) means the changes in the macular region, when the tumor is located at the distant from it. Purpоse: to study the peculiarities of the DM development, according to the tumor localization and present a possible mechanism of this symptom development. Patients and Methods. The study involved 53 patients with choroidal tumors localized outside the macular area, including 18 patients with neuroepithelial detachment (NED) in the macular area. In addition to the standard eye examination, all patients underwent EDI OCT. Results. In 1/3 cases of extrafoveolar located choroidal tumors according to OCT, exudative changes in the macular zone were revealed. In extrafoveral choroidal melanoma (CM), the biometric tumor parameters in patients with DM were slightly higher than the average in patients of this group, however, there was no correlation between the height of NED and tumor parameters. In extrafoveolar choroidal hemangioma (CH), a significant direct relationship between the height of the NED in the foveolar zone and the biometric parameters of the CH was found. In all cases, there was not choroidal elevation in the foveolar zone. The thickness and structure of the choroid in the subfoveolar zone in CM did not differ from the paired eye and the normal values. The thickness of the choroid in CH also did not differ from the paired eye, however, there was a slight expansion of the outer layers of the choroid (as in the paired eye) and an increase in its thickness compared with the norm. When a tumor is located above the macular zone, there is a “gravitational” mechanism for the development of DM, due to the spread of subretinal fluid (or blood) under the action of gravity. In case of juxtapapillar tumor localization, the appearance of DM is caused by microvascular disorders in the foveo-macular region of the retina and impaired axoplasmic current. In CM, the occurrence of NED may be associated with a retinal tension on the steeper side of the tumor. Conclusion. The development of distant maculopathy in CM is a sign of “active” tumor growth, in CH it develops later and depends on the size of the tumor. In identifying a high prevalent NED in the macular area, a careful examination of not only the central fundus zone, but also its peripheral parts is necessary.
Comparative Analysis of Double and Trifocal IOL Implantation in Femtosecond Laser-Assisted Cataract Surgery
Authors: Orenburkina O. I. 
Published: April 2019

Purpose: to compare the clinical results of implantations of bi-and trifocal intraocular lenses (IOL) in femtosecond laser-assisted cataract surgery. Patients and methods. The article presents the results of the Acrysof IQ Panoptix trifocal lens implantations in 84 patients (112 eyes) — the main group and Acrysof IQ Restor bifocal IOL implantations in 52 patients (98 eyes) — the control group. All patients underwent femtosecond laser-assisted cataract surgery (FLACS). The following data were evaluated: uncorrected distance visual acuity (UCDVA) , uncorrected near visual acuity (30–45 cm) and at an average distance (50–70 cm) at discharge, after 14 days, 1 and 3 months after the surgery under photopic and mesopic lighting conditions. Postoperative refractometry data; the defocusing curve was performed in patients with a high UCDVA (0.9–1.0) monocularly under photopic conditions using standard optotypes 14 days after surgery; aberrometry indicators. Results. It was shown that both lenses provided high uncorrected distance and near visual acuity in photopic lighting conditions. At the same time, the Acrysof IQ Panoptix lens provided significantly better visual acuity at an intermediate distance and was more resistant to defocusing conditions. Refraction data: after 1 month, emmetropia was observed in 87 % of patients in the main group and in 85 % of control group, after 6 months — 92 and 89 % respectively. There were no significant differences in high order aberrations and total aberrations between patients of the compared groups. Conclusion. The use of the PanOptix trifocal lens made it possible to obtain maximum visual acuity at different distances, regardless of the level of illumination.
Functional outcome of elbow joint in AO type 13C fractures treated with open reduction and internal fixation using dual plates
Authors: Sreedhar Reddy Uyyalawada , Samorekar Bheemsingh , Mathew Vinay J. , Mettu Anil Kumar 
Published: April 2019

<p class="abstract"><strong>Background:</strong> Distal end of the humerus, with its unique orientation of articular surfaces supported by a meagre amount of cancellous bone, makes its fracture a constant challenge to orthopaedic surgeons. Aim of the study is to evaluate the functional outcome of surgical management of intercondylar AO type C fractures of distal end of humerus using dual plating.</p><p class="abstract"><strong>Methods:</strong> A prospective study was conducted at our hospital between January 2015 to December 2016. Thirty five consecutive patients with intercondylar (AO Type C) fracture of distal humerus, included in study as per inclusion criteria. All patients were treated surgically using triceps reflecting approach and posterior trans-olecranon approach with ulnar nerve exploration and fixation using dual plating and tension band wiring for olecranon osteotomy wherever done.<strong></strong></p><p class="abstract"><strong>Results:</strong> In 35 patients, final results using MEPS scoring system excellent outcome is noticed in 15 patients (42.86%), good results is noticed in 13 patients (37.14%), fair result is noticed in 5 patients (14.29%) and poor result is noticed in 2 patients (5.71%). There was statistical significant difference in flexion range of movement arc at 2 and 6 months in our study.</p><p class="abstract"><strong>Conclusions:</strong> Open reduction and internal fixation of AO type 13C fractures is challenge to surgeon, preoperative planning and mastering the technique over a period of time gives good to excellent functional outcomes.</p><p class="abstract"> </p>
ІННОВАЦІЙНО-ІНВЕСТИЦІЙНИЙ РОЗВИТОК ПРОМИСЛОВОСТІ УКРАЇНИ
Authors: Babenko K. , Iarmosh O. , Malykhina Y. , Fedorova Y. 
Published: April 2019

Сучасні дослідження технологічного розвитку України свідчать про подальший розвиток вітчизняної економіки в руслі експортно-сировинної моделі, спостерігається переривання технологічного ланцюжка у циклі металургійно-машинобудівного виробництва, що призводить до неефективного використання сировинного запасу країни. Збільшення виробництва, що засновано на природних ресурсах, веде до спадаючої віддачі і тому до збіднення країни в цілому. Історична та сучасна світова практика доводить, що країна може вирішити проблеми економічної відсталості лише шляхом індустріалізації та захисту нових виробництв. Розвиток виробництв більш високих технологічних укладів неможливий без підтримки держави. Відправними точками інноваційного та інвестиційного зростання в Україні можуть стати об’єднання з вертикальною інтеграцією. Сучасний глобальний економічний простір побудовано на інтеграційних структурах. Для України найбільшими інтеграційними структурами з максимальним синергетичним ефектом можуть бути оновлені промислово-фінансові групи, учасниками яких будуть пов'язані технологічними ланцюжками промислові підприємства та банківські структури.Виходячи зі специфіки вітчизняної економіки, яка спирається на металургійний комплекс, вважаємо за доцільне перехід до збільшення виробництва металоємкої машинобудівної продукції. Зосередження на розвитку внутрішнього ринку шляхом інвестиційної підтримки машинобудівної галузі означає для України унікальну можливість надати економіці системність, збалансованість, синергію та соціально орієнтований характер. Продовження базових технологічних ланцюжків шляхом активного залучення машинобудівних підприємств до промислово-фінансових груп з металургійним виробництвом за підтримки банків-учасників дозволить отримувати економічні ефекти на макро- та мікрорівнях, а такі групи визначати як "точки зростання" інноваційного та інвестиційного піднесення в країні. Досліджено складові синергетичного ефекту, а саме комутаційний, операційний, управлінський, інвестиційний та інноваційний синергетичні ефекти, що мають місце у промислово-фінансових групах з вертикальною інтеграцією.
FEATURES OF REGULATORY IDENTIFICATION OF FINANCIAL COMPANIES AS FINANCIAL INTERMEDIARIES
Authors: Naumenkova S. V. , Mishchenko S. V. , Mishchenko V. I. 
Published: April 2019

In recent years,Ukrainehas witnessed a rapid increase in the number and intensification of financial companies' activities in the financial services market, which is increasing the attention to this type of financial intermediaries. The generalization of historical experience suggests that financial companies in various forms began to operate in foreign countries from the 1960s, but they have become the most widespread in theUnited States. On the basis of the Federal Reserve System data processing for the period of 2005 - 2017, results were obtained that characterize the peculiarities of the activities of financial companies in such segments of the financial services market as consumer lending, car loans, auto leasing. The main criteria for identifying financial companies in theUnited Statesare requirements for the structure of assets, which provides a clearer definition of the use of regulatory measures and restricts the competition between financial intermediaries.The study concluded that in Ukraine the criteria for identifying financial companies need to be clarified in terms of specifying regulatory requirements, limiting the risks associated with financial assets in the provision of financial services, as well as preventing possible loss of capital and timely fulfillment obligations to customers. The cooperation of financial companies with banks and other non-bank financial intermediaries, such as lenders and credit brokers, working in the consumer lending service segment needs regulatory clearance. The emphasis is placed on the need for harmonization of Ukrainian legislation in accordance with international practice in order to stimulate the further development of the financial intermediary institution in Ukraine.