bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crystal structure of 3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid, C7H3ClF3NO2
Authors: Pan Xiaoru , Kong Xiang-Yan 
Published: November 2024

Abstract
C7H3ClF3NO2, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 5.8837(5) Å, b = 14.1634(14) Å, c = 15.3120(15) Å, α = 92.667(5)°, β = 100.364(5)°, γ = 99.475(5)°, V = 1,234.2(2) Å3, Z = 6, R
gt(F) = 0.0458, wR
ref(F
2) = 0.1012, T = 298 K.
A 9–10. századi eurázsiai íjászfelszerelés változásainak okai a kísérleti régészet szemszögéből
Authors: Türk Attila , Wilhelm Ákos Sándor , Paku Sándor 
Published: November 2024

AbsztraktA hun korban megjelenő, legtöbbször íjmerevítőnek nevezett agancslemezek a 9–10. századra jelentős átalakuláson mentek keresztül, sőt ezt követően rövid időn belül teljesen eltűntek. Dolgozatunk ennek okát igyekszik feltárni. Felmerült annak a lehetősége, hogy ezek az agancslemezek az íjak felépítésében lévő ragasztások megerősítésére jelenhettek meg, majd az íjak a ragasztási módok fejlődésével erősítés nélkül is sokkal erősebbekké, tartósabbakká váltak. Ebben az időszakban jelent meg a felajzott íj viselésére szolgáló készenléti íjtegez is. Ennek használatát talán pont az tette lehetővé, hogy az íjak szerkezetének megváltozása alkalmassá tette azokat a hosszabb ideig történő felajzva tartásra. A hosszabb ideig felajzva tartható íj nemcsak a felajzás körülményességét spórolta meg, de komoly harcászati előnyt is jelenthetett viselője számára.
The use of Slovakia Hungarian dialects in social media
Authors: Presinszky Károly 
Published: November 2024

AbstractThis paper analyzes dialect-stylizing internet content on current events that depict Slovakia Hungarian dialects speakers. The regular display of dialect phenomena on social media platforms allows rapid spread, constant presence, and the possibility of comments. The figure of the dialect speaker, previously geographically bounded, can become a symbol of authenticity, accessible from anywhere in the world. The paper examines the importance of the views of lay language users and content creators in simple language management and citizen science in the contexts of the recognition of dialects, of their oral and written representation, and of the evaluation of languages and varieties.
PENGARUH ECONOMIC VALUE ADDED (EVA) DAN PRICE TO BOOK VALUE (PBV) TERHADAP STOCK PRICE PADA PERUSAHAAN YANG TERDAFTAR DI JAKARTA ISLAMIC INDEX (JII) (Studi Kasus di PT. Timah tbk Periode 2013-2022)
Authors: Mila Mila Badriyah , Aldi Aldi Nurhikmah 
Published: November 2024

Penelitian ini dilatarbelakangi adanya ketidaksesuaian data yang ditemukan oleh peneliti pada PT. Timah Tbk dengan teori yang telah ada. Teori menyatakan bahwa jika Economic Value Added dan Price to Book Value atau dalam penelitian ini di jadikan variabel X1 dan X2, dimana perusahaan mengalami peningkatan diikuti dengan Stock Price (Harga Saham) dijadikan variabel Y. Hasil penelitian menunjukan bahwa; 1) Economic Value Added secara parsial tidak berpengaruh signifikan terhadap Stock Price dengan persamaan Stock price = 0.105 + 0.000 Economic Value Added dengan nilai korelasi sebesar 0.472. Interpretasi nilai kriteria hubungan korelasi dari keduanya adalah sedang dan nilai thitung sebesar 1.513 atau nilai thitung < ttabel (1.513 < 2.306) dengan nilai signifikasi 0.169 > 0.05; 2) Price to Book Value (PBV) secara parsial berpengaruh signifikan, dengan persamaan Stock price = -0.012 + 0.083 Price to Book Value dimana nilai korelasi sebesar 0.911. Interpretasi nilai kriteria hubugan korelasi dari keduanya adalah sangat kuat dan nilai thitung sebesar 6.233 atau nilai thitung > ttabel (6.233>2.306) dengan nilai signifikasi 0.00<0.05; 3) Secara simultan variabel berpengaruh signifikan terhadap Stock Price dengan interpretasi nilai kriteria hubugan korelasi secara simultan adalah sangat kuat dengan nilaiFtabel sebesar 4.734 atau Fhitung > Ftabel (29.188 > 4.734).
Search for genetic predictors of acute coronary syndrome in patients after coronavirus disease 2019
Authors: Kozik V. A. , Shpagina L. A. , Shpagin I. S. , Minnikh S. V. , Lozhkina N. G. , Maksimov V. N. 
Published: November 2024

Aim. To assess the rs2285666 nucleotide sequence of the angiotensin-converting enzyme 2 (ACE2) gene and its association with acute coronary syndrome (ACS) in patients after coronavirus disease 2019 (COVID-19).Material and methods. The study included 100 patients after COVID-19, including 50 men and 50 women, hospitalized with a diagnosis of ACS. The diagnosis of COVID-19 in all 100 patients was confirmed by a positive polymerase chain reaction (PCR) smear. All patients underwent percutaneous transluminal coronary angioplasty with stenting, standard clinical and paraclinical examination, and genetic testing of the rs2285666 ACE2 gene by PCR followed by restriction fragment length polymorphism analysis. The comparison group consisted of 200 patients with ACS after COVID-19, confirmed by a PCR smear or antibody titer.Results. Statistically significant differences were obtained for the AA genotype, carriage of which among male patients with ACS after COVID-19 was 2,5 times less common than in men in the control group (OR =0,391, 95% CI: 0,167-0,917; p=0,028). On the other hand, carriage of the rs2285666 GA genotype of the ACE2 gene is not associated with an increased risk of ACS in women after COVID-19. There were no significant differences in genotype frequencies in the group of women and in the general group (without division by sex).Conclusion. The data obtained may indicate a protective role of the rs2285666 AA genotype of the ACE2 gene for males regarding ACS development after COVID-19. These results are the first steps towards building a prognostic model to estimate the ACS risk in patients after COVID-19, which will reduce morbidity and mortality for this group of patients.
Relationship of EDNRA rs6842241 and MRAS rs9818870 polymorphic variants with predisposition to coronary artery disease and their effect on the lipid-lowering effect of rosuvastatin
Authors: Kononov S. I. , Azarova Yu. E. , Klyosova E. Yu. , Bykanova M. A. , Solodilova M. A. , Polonikov A. V. 
Published: November 2024

Aim. To study the effect of EDNRA rs6842241 and MRAS rs9818870 polymorphic variants on the lipid-lowering effect of rosuvastatin in patients with coronary artery disease (CAD), and to determine the role of these loci in the development of CAD among Central Russia residents.Material and methods. The pharmacogenetic study involved 116 patients with class II-III stable angina. Patients received rosuvastatin with dose titration to achieve target low-density lipoprotein cholesterol (LDL-C) levels. The genetic and epidemiological study included DNA samples of 1960 Central Russia residents (1261 patients with CAD and 699 healthy individuals). Genotyping of polymorphic variants was performed on a MassARRAY-4 genomic mass spectrometer. Associations of polymorphisms with lipid changes for 1, 6 and 12 months of follow-up were calculated using linear regression analysis adjusted for sex, age, body mass index and rosuvastatin dose; associations with CAD risk — using logistic regression analysis adjusted for sex and age. The statistical significance of associations was calculated using the permutation test.Results. Carriage of the AA and CA genotypes of EDNRA rs6842241 variant was associated with a weakening of the rosuvastatin lipid-lowering effect in relation to total cholesterol (β=0,075, p=0,001) and LDL-C (β=0,145, p=0,017) at the end of the first month and 12 months of therapy (β=0,049, p=0,013 and β=0,072, p=0,040, respectively). Carriage of the AA genotype of EDNRA rs6842241 variant was associated with an increased CAD risk (odds ratio 5,36; 95% confidence interval 1,62-17,71, p=0,004). MRAS rs9818870 variant was not associated with rosuvastatin pharmacogenetics or with the CAD risk. Both polymorphic variants were not associated with lipid levels outside of lipid-lowering therapy, as well as with the triglyceride changes. High-density lipoprotein cholesterol levels during the entire follow-up period changed insignificantly.Conclusion. The EDNRA rs6842241 variant is associated with both a weakening of the lipid-lowering effect of rosuvastatin in CAD and an increased risk of its development in the population.
Anthropometric parameters as risk factors for dilated cardiomyopathy in carriers of rs1805124 and rs35068180 polymorphisms
Authors: Kuznetsova O. O. , Nikulina S. Yu. , Chernova A. A. , Maksimov V. N. 
Published: November 2024

Aim. To identify anthropometric parameters that are associated with a more frequent development of dilated cardiomyopathy (DCM) in patients with rs1805124 and rs35068180 polymorphisms.Material and methods. The present study included 111 patients with idiopathic dilated cardiomyopathy (DCM) (99 men (89,2%) and 12 women (10,8%)). The mean age of the participants was 51±9,1 years, with an age range of 20 to 69 years. The control group included 101 healthy individuals (mean age, 50,8±12,3 years; age range, 34 to 79 years (men, 86,1%)).The Rees-Eysenck index (body length*100/chest transverse diameter*6) and the Tanner's sexual dimorphism index (3*shoulder diameter–intercrestal diameter) were used.In addition to the conventional body mass index (BMI), the study determined waist circumference, hip circumference, body shape index (BSI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body adiposity index (BAI), body roundness index (BRI).Results. Patients carrying the GG genotype had significantly higher WHR, BAI, and BRI indices compared to the control group. However, similar differences were also observed among carriers of the AG and AA genotypes. Also, carriers of the AG and AA genotypes of the rs1805124 polymorphism significantly differed from the control group in WHR and WHtR. This may indicate the primary influence of somatometric indices, rather than the studied polymorphisms, on the DCM development.The multivariate analysis performed using the Wald stepwise selection method showed a significant effect of BRI (p=0,000) and the Rees-Eysenck index (p=0,000) on the development of DCM in carriers of the rs1805124 polymorphism GG genotype. In patients carrying the 6a/6a genotype, the WHtR, WHR, BMI, BAI, and BRI were significantly higher than in the control group. Similar differences were also observed among carriers of the 6a/5a genotype. The indices of WhtR, BAI, BMI, and BRI were significantly higher in carriers of the 5a/5a genotype. However, similar differences were also observed among carriers of the AG and AA genotypes. Also, carriers of the AG and AA genotypes of the rs1805124 polymorphism significantly differed from the control group in both WHR and WHtR.Conclusion. Most likely, such somatometric indices as BRI, WHR, WHtR, BAI, and BMI are of great importance in the development of DCM. In carriers of the homozygous rare allele G of the rs1805124 polymorphism, independent predictors of DCM may be BRI and the Rees-Eysenck index, while in carriers of the rare allele 5a of the rs35068180 polymorphism — BRI, BMI, and the Rees-Eysenck index. However, BRI and the Rees-Eysenck index may be independent predictors of DCM regardless of the genotypes of the studied polymorphisms.
Between Private and Public: Rethinking Hannah Arendt’s Notion of ‘Natality’ Through Contemporary Feminist Thought
Authors: Argirò Anna 
Published: November 2024

This article re-examines Arendt’s notion of ‘natality’ through a reinterpretation of her public-private distinction as dynamic, and engaging specifically with feminist reflections on ‘the maternal’ as provided by Adriana Cavarero and Judith Butler. As the human capacity of beginning something new, Arendt’s concept of ‘natality’ implies that human beings come into the world not as self-generated, but as related to others. Nonetheless, this notion has been criticized for abstracting from the concrete experience and generative process of birth. More generally, it has often been argued that Arendt separates human beings’ first appearancein the world through birth from their capacity to appear in the shared scene of political life. Building on feminist reflections on maternity and suggesting an interpretation of Arendt’s public/private distinction as dynamic, this article shows that the private sphere exhibits its plurality and embodiment through intimate relations that inform the political space. This way, it argues that the interplay between what Arendt calls ‘first and second birth’ can be rethought as non-exclusive but connected, reconsidering the ‘first birth’ as a political and existentially significant event already staged within a network of relations.
Duration Models for Subduction Earthquakes
Authors: Pinilla-Ramos Camilo I. , Abrahamson Norman A. 
Published: November 2024

ABSTRACT
An empirical model for the significant duration of acceleration for subduction zone earthquakes is developed based on the normalized Arias intensity. The data set is a subset from the Next Generation Attenuation-Subduction database (Bozorgnia and Stewart, 2020). The functional form of the duration model uses an additive model for the source, path, and site terms with three lognormally distributed random effects for the source, path, and site. The remaining aleatory variability is modeled by a power-normal distribution. There are two parts of the duration model: a model for the D5–75 duration and a model for the D5–X/D5–75 ratio, which can be combined with the D5–75 model to estimate the DY–X for any interval. The D5–75 model includes regionalized coefficients for Japan, New Zealand, South America, and Taiwan. The large-magnitude (M &gt;7) scaling of the D5–75 model is much weaker than the recent duration model by Bahrampouri et al. (2021). The residuals of the D5–75 model are negatively correlated with the lnPGA residuals with a correlation coefficient of −0.50 such that above-average peak ground acceleration values are associated with below-average duration values.
A Note on Oral Health, and on the Future of the North Carolina Medical Journal
Authors: Morris Peter J. 
Published: November 2024

With this issue, the North Carolina Medical Journal ceases to publish in print and will appear exclusively online. The NCMJ will reach back almost 175 years to our founding in 1849 and will once again focus on peer-reviewed original research. Dr. Ronny Bell assumes to role of Editor-in-Chief.
Nuts and Bolts of Dental Medicaid Managed Care
Authors: Couch James W. , Slawinski Heather 
Published: November 2024

North Carolina has adopted managed care for administration of its Medicaid program for management of medical benefits. The North Carolina Medicaid dental program, however, continues to be administered through a traditional fee-for-service model. This article addresses what a managed care model for Medicaid dental could look like in North Carolina.
Ksiądz profesor Walerian Meysztowicz w Rzymie (działalność naukowa, dyplomatyczna i społeczna)
Authors: Przeniosło Małgorzata , Przeniosło Marek 
Published: November 2024

Walerian Meysztowicz urodził się w 1893 r. w zamożnej rodzinie ziemiańskiej w Pojościu (majątek w guberni kowieńskiej). Jego ojcem był Aleksander, działacz polityczny i społeczny, związany z kierunkiem konserwatywnym. Walerian w 1924 r. został księdzem katolickim, na jego drodze życiowej pojawiły się też liczne inne wyzwania, związane szczególnie z karierą akademicką i dyplomatyczną, a także z zaangażowaniem o charakterze społeczno-naukowym. Ten ostatni obszar realizował w szerokiej skali po opuszczeniu w 1939 r. kraju i zamieszkaniu na stałe w Rzymie. W przypadku drogi naukowej w tekście znalazły się informacje na temat uzyskiwanych kolejnych stopni i tytułów naukowych (doktorat – Rzym, habilitacja i profesura – Wilno). Pobyt Meysztowicza w Rzymie początkowo wiązał się z powierzeniem mu funkcji radcy kanonicznego Ambasady RP w Watykanie. Po wybuchu II wojny światowej na stałe wyjechał z kraju i przez ponad 40 lat angażował się w inicjatywy, których celem było prowadzenie badań dotyczących dziejów ojczystych, także upowszechnianie tych badań. Bohater artykułu w 1945 r. założył Polski Instytut Historyczny w Rzymie, zainicjował i koordynował liczne przedsięwzięcia wydawnicze z zakresu historii Polski, szczególnie będące edycją źródeł. Zmarł w Rzymie w 1982 r.
Spuścizna archiwalna archidiecezji lwowskiej i diecezji przemyskiej obrządku łacińskiego w państwowych instytucjach Zachodniej Ukrainy po 1946 r.
Authors: Wołczański Józef 
Published: November 2024

II wojna światowa przyniosła całkowitą zagładę struktur administracyjnych archidiecezji lwowskiej i wschodnich dekanatów diecezji przemyskiej obrządku łacińskiego na powojennym obszarze Związku Sowieckiego. W ramach ewakuacji instytucji pierwszej z wymienionych w 1946 r. w granice Polski, zdołano ocalić zdecydowaną większość zasobów Archiwum Archidiecezjalnego we Lwowie. Na miejscu pozostała wszakże pewna ilość materiałów archiwalnych.
W Centralnym Państwowym Historycznym Archiwum Ukrainy we Lwowie znajdują się zespoły: Rzymskokatolicki Konsystorz Metropolitalny we Lwowie 1790-1939, fond 618, op. 1; Rzymskokatolicki Konsystorz Metropolitalny we Lwowie 1361-1948 – Księgi Metrykalne 1600-1948, fond 618, opis 2; Rzymskokatolicka Kuria Metropolitalna we Lwowie do roku 1939, fond 831, opis 1; Rzymskokatolickie Seminarium Duchowne we Lwowie 1790-1939, fond 832, nr 1; Rzymskokatolicka Kapituła Metropolitalna we Lwowie 1417-1939, fond 197, opis 1; Rzymskokatolicka Kapituła Metropolitalna we Lwowie 1429-1939, fond 197, opis 2. Ponadto na uwagę zasługuje zasób rzymskokatolickiego Urzędu Dekanalnego w Żółkwi za okres XV-XX wiek, fond 778, opis 1; rzymskokatolickiego Urzędu Parafialnego w Glinianach 1397-1939, fond 815, opis 1; oraz rzymskokatolickiego Urzędu Parafialnego w Jaworowie 1454-1939, fond 127, opis 1.
W zasobach Państwowej Rejestracji Akt Stanu Cywilnego obwodu lwowskiego we Lwowie przechowywane są księgi metrykalne parafii rzymskokatolickich archidiecezji lwowskiej i diecezji przemyskiej w granicach obecnej Ukrainy. W Państwowym Archiwum Obwodowym w Iwano-Frankiwsku mieszczą się metrykalia z obszaru byłego województwa stanisławowskiego (dziś iwano-frankiwskiego), wytworzone przez parafie archidiecezji lwowskiej. Państwowe Archiwum Obwodowe w Tarnopolu dysponuje analogicznymi materiałami źródłowymi parafii z byłego województwa tarnopolskiego, również wchodzących w skład struktury administracyjnej lokalnego Kościoła lwowskiego.
INTERNACIONALIZAÇÃO DA EDUCAÇÃO SUPERIOR: outras regionalidades
Authors: Rubin-Oliveira Marlize , Zambiasi Fábio 
Published: November 2024

O tema da internacionalização da Educação Superior (ES) cresceu nas últimas décadas e ocupa espaço significativo nas agendas das universidades e políticas públicas. O objetivo do artigo é problematizar a racionalidade moderna/colonial, com foco na categoria regionalidade, visando compreender a universidade e a internacionalização da ES como pilar do modelo universalizante de ciência. O caminho teórico-metodológico, a partir da decolonialidade, busca identificar e discutir movimentos e tensionamentos próprios da racionalidade moderna/colonial, que se impôs à universidade e, constrói modelos de internacionalização. A partir de experiências de duas universidades - Universidade Popular dos Movimentos Sociais (UPMS) e das U.S. Tribal Colleges and Universities (TCUs) - identificamos outras regionalidades que tensionam e constroem distintas e diversas possibilidades de universidade e internacionalização, a partir de outras realidades, sensibilidades e cosmovisões.
Effect of Stocking Density on Selected Blood Physiological, Biochemical and Enzymatical Variables of Broilers Grown to 3 kg under Antibiotic-free Conditions
Authors: Olanrewaju Hammed A. , Magee Christopher L. , Collier Stephanie D. , Purswell Joseph L. 
Published: November 2024

Background: Reducing stocking densities may play a key role in minimizing difficulties such as physiological welfare when reducing or ending antimicrobials in poultry diets. As the demand for poultry and associated products increases, one of the major concerns centers on the question of whether stocking density influences welfare responses that are characteristic of physiological welfare. This study investigated the effect of stocking density on selected blood physiological variables along with plasma biochemistry variables and enzymes activities of broilers fed antibiotic-free diets grown to 3 kg. Methods: A total of 888 1-d-old Ross ´ Ross 708 chicks were randomly distributed into 24 pens based on stocking density treatments assignment. The treatments consisted of 4 densities (29, 33, 39 and 42 kg/m2) with six replicates. Treatments were blocked within the room to account for any variations in room conditions. Treatment assignments were randomized within each block. Used litter bedding was obtained from commercial farms to mimic commercial conditions and litter microflora. Birds were provided a three phase-feeding program (Starter: 0-14 d, Grower: 15-28 d and Finisher: 29-42 d) antibiotic-free diets. Feed and water provided ad libitum. Blood samples were collected from the brachial wing vein of 3 males and 3 females’ birds per pen on d 28 and 42 and analyzed immediately for blood physiological variables. Blood plasma samples were analyzed for T3, T4, corticosterone, biochemical variables and enzyme activities. Result: The only effect of stocking density was observed on partial pressure of CO2 (pCO2) and uric acid which were within physiological ranges for this species. However, blood glucose and plasma corticosterone concentrations were not affected by stocking density, suggesting no signs of physiological stress. Stocking densities up to 42 kg/m2 with proper environmental management may be suitable for both poultry integrators and contract growers to enhance broilers production efficiency without compromising the welfare of broilers grown to 3 kg body weight.
Pathogenic NLRP3 mutants forms constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production
Authors: Pelegrin Pablo , Molina-Lopez Cristina , Hurtado-Navarro Laura , García Carlos , Angosto Diego , Vallejo Fernando , Tapia-Abellán Ana , Marques-Soares Joana , Vargas Carmen , Bujan-Rivas Segundo , Tomas-Barberan Francisco , Aróstegui Juan 
Published: November 2024

Abstract

Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory condition resulting from monoallelic NLRP3 variants that facilitate IL-1β production. Although these are gain-of-function variants characterised by hypersensitivity to cell priming, patients with CAPS and animal models of the disease may present inflammatory flares without identifiable external triggers. Here we find that CAPS-associated NLRP3 variants are forming constitutively active inflammasome, which induce increased basal cleavage of gasdermin D, IL-18 release and pyroptosis, with a concurrent basal pro-inflammatory gene expression signature, including the induction of nuclear receptors 4A. The constitutively active NLRP3-inflammasome is responsive to the selective NLRP3 inflammasome inhibitor MCC950 and its activation is regulated by deubiquitination. Despite their preactivated state, the CAPS inflammasomes are responsive to activation of the NF-κB pathway. NLRP3-inflammasomes with CAPS-associated variants affect the immunometabolism of the myeloid compartment, leading to disruptions in lipids and amino acid pathways and impaired glycolysis, limiting IL-1β production. In summary, NLRP3 variants causing CAPS form a constitutively active inflammasome inducing pyroptosis and IL-18 release without cell priming, which enables the host's innate defence against pathogens while also limiting IL-1β–dependent inflammatory episodes through immunometabolism modulation.