bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crime and victimization among people with intellectual disability with and without comorbid mental illness
Authors: Thomas Stuart D. M. , Nixon Margaret , Ogloff James R. P. , Daffern Michael 
Published: April 2019

AbstractBackgroundAccumulating evidence internationally points to an increased risk of crime perpetration and victimization among people with an intellectual disability (ID). This study aimed to examine the impact that comorbid mental illness had on the association between intellectual disability, crime perpetration and criminal victimization.MethodA case linkage methodology involving 2,220 individuals with an intellectual disability from an Australian State.ResultsOne in four (27%) had contacts with public mental health services; 8.2% had a comorbid mental illness. This “dual disability” group was between 2.97 and 3.22 times more likely than those with intellectual disability alone to have a history of criminal charges, and between 2.76 and 2.97 times more likely to have been a victim of crime.ConclusionsThe extent of criminality and victimization found among people with dual disability indicates a potentially multiply stigmatized group for whom the need for a coordinated cross‐agency service response remains paramount.
Exploring Disparities in Influenza Immunization for Older Women
Authors: MacCarthy Sarah , Burkhart Q , Haviland Amelia M. , Dembosky Jacob W. , Wilson‐Frederick Shondelle , Saliba Debra , Gaillot Sarah , Elliott Marc N. 
Published: April 2019

OBJECTIVESWhile women obtain most recommended preventive health interventions more often than men, evidence is mixed regarding influenza vaccination for older adults. Therefore, we evaluated sex differences in influenza vaccination among older adults.DESIGNNationally representative cross‐sectional survey.SETTINGUnited States.PARTICIPANTSA total of 1 252 705 adults, aged 65 years and older, responding to 2013 to 2017 Medicare Consumer Assessment of Healthcare Providers and Systems surveys.MEASUREMENTSThe dependent variable was Healthcare Effectiveness Data and Information Set self‐reported influenza immunization. The primary predictor was sex. Covariates included general health status, education, race/ethnicity, and Medicare Advantage (MA; managed care) vs Fee‐for‐Service (FFS) coverage.RESULTSAfter adjusting for health status and other sociodemographic factors, women's immunization was 2% lower than men's immunization in MA, with no significant overall sex difference in FFS. Women were immunized less often than men in 95% of MA health plans, with the largest gaps in low‐immunizing plans. Further analyses revealed variation in sex differences by health status, education, and race/ethnicity in both MA and FFS. Notably in MA, women in poor health were immunized less often than men in similar health (−4%; P < .001). Black women were immunized much less often than black men in both MA and FFS (−5%; P < .001 for each). Hispanic women were immunized less often than Hispanic men in MA (−4%; P < .001) but not within FFS.CONCLUSIONWomen in MA experience small disparities overall in influenza immunization, with larger disparities for black and Hispanic women. Providers and MA plans should increase efforts to recommend and monitor immunization for older women, especially black and Hispanic women and those in poor health. Given the potential to reduce morbidity and mortality, equitable access to a critical preventive health service, such as influenza immunization, is crucial for all older adults.
Flexible assertive community treatment for individuals with a mild intellectual disability or borderline intellectual functioning: results of a longitudinal study in the Netherlands
Authors: Neijmeijer L. J. , Korzilius H. P. L. M. , Kroon H. , Nijman H. L. I. , Didden R. 
Published: April 2019

AbstractBackgroundAssertive community treatment (ACT) and Flexible assertive community treatment (FACT) are organisation models for intensive assertive outreach that were originally developed for individuals with severe mental illness. The models are increasingly applied to people with mild intellectual disability (MID) or borderline intellectual functioning (BIF) and challenging behaviour or mental illness. Research on these types of care for this population is limited. To gain experience in FACT MID/BIF in the Netherlands and to obtain insight in its outcomes, four organisations specialised in the treatment of individuals with MID/BIF and challenging behaviour participated in a 6‐year implementation and research project.MethodsA longitudinal study was set up to investigate outcomes over time. Outcome measures concerned admissions to (mental) health care, social and psychological functioning, (risk of) challenging and criminal behaviour, social participation and client satisfaction. Data were analysed using descriptive statistics and linear mixed models.ResultsOver time, clients showed improvement in their social and psychiatric functioning and living circumstances. The number of admissions to (mental) health care diminished as well as the number of contacts with police and justice, the level of social disturbance and the risk factors for challenging and criminal behaviour. Problems related to finances, work and substance abuse remained unchanged.ConclusionsThe results are encouraging and give rise to continued development of and broader research on FACT MID/BIF.
Broken smiles: The impact of untreated dental caries and missing anterior teeth on employment
Authors: Halasa‐Rappel Yara A. , Tschampl Cynthia A. , Foley Mary , Dellapenna Martha , Shepard Donald S. 
Published: April 2019

AbstractObjectivesWe aimed to quantify the impact of dental caries and missing anterior teeth on employment, estimate the impact of a routine dental visit on the health of anterior teeth, and the benefits of expanding dental coverage for nonelderly adults.MethodsWe used the 2013–2014 Continuous National Health and Nutritional Examination Survey to develop a dental problem index (DPI) using tooth counts and tooth surface conditions. We estimated the impact of DPI on employment with logistic regression, controlling for seven demographic and socioeconomic covariates. We used a routine dental visit within 6 months as a proxy for access to dental services, and a linear regression to predict the DPI score for an average individual with and without a recent routine dental visit. We then computed the incremental probability of employment associated with a recent routine dental visit. Finally, we estimated the additional number of working age adults who might become employed due to improved access to dental services.ResultsThe probability of being employed was negatively associated with poor oral health: a one‐point increase in DPI decreased the odds of being employed by 7.70 percent (CI: 5.15–10.19%). Having a routine dental visit had a negative and statistically significant impact on DPI [−0.41 (CI: −0.68 to −0.14)]. The incremental probability of employment associated with a routine dental visit was 0.62 percent (CI: 0.21–1.03%).ConclusionsOral health in the United States is worse among minorities and poor than among other residents. The benefits associated with access to dental care should justify expanding dental services.
Differential feeding by common heterotrophic protists on four Scrippsiella species of similar size
Authors: Kim So Jin , Jeong Hae Jin , Kang Hee Chang , You Ji Hyun , Ok Jin Hee 
Published: April 2019

The dinoflagellate genus Scrippsiella is known to cause red tides. Mortality due to predation should be assessed in order to understand the population dynamics of Scrippsiella species. However, predation has been explored only in a few species. In this study, we examined feeding by common heterotrophic dinoflagellates Oxyrrhis marina, Gyrodinium dominans, Polykrikos kofoidii, Oblea rotunda, and Pfiesteria piscicida, and a ciliate Strombidinopsis sp., on four Scrippsiella species, of similar size, namely Scrippsiella acuminata, Scrippsiella donghaiensis, Scrippsiella lachrymosa, and Scrippsiella masanensis. All the heterotrophic protists tested could feed on all the four Scrippsiella species. However, the numerical and functional responses of P. kofoidii to the mean prey concentration were apparently different between the Scrippsiella species. With increasing prey concentration, the growth and ingestion rates of P. kofoidii on S. lachrymosa increased rapidly, and then saturated similar to those on S. acuminata, as previously reported, but those on S. donghaiensis continuously decreased. The cells of S. donghaiensis lysed P. kofoidii cells. In contrast, the growth and ingestion rates of P. kofoidii on S. masanensis were not significantly related to the prey concentration. At similarly high mean prey concentration, the growth and ingestion rates of G. dominans were significantly different between the four Scrippsiella species Therefore, differences in the growth and/or ingestion rates of G. dominans and P. kofoidii on the four Scrippsiella species might result in different ecological niches of both the predator and prey species.
RNAi of the sesquiterpene cyclase gene for phytoalexin production impairs pre‐ and post‐invasive resistance to potato blight pathogens
Authors: Yoshioka Miki , Adachi Ayako , Sato Yutaka , Doke Noriyuki , Kondo Tatsuhiko , Yoshioka Hirofumi 
Published: April 2019

SummaryPotato antimicrobial sesquiterpenoid phytoalexins lubimin and rishitin have been implicated in resistance to the late blight pathogen, Phytophthora infestans and early blight pathogen, Alternaria solani. We generated transgenic potato plants in which sesquiterpene cyclase, a key enzyme for production of lubimin and rishitin, is compromised by RNAi to investigate the role of phytoalexins in potato defence. The transgenic tubers were deficient in phytoalexins and exhibited reduced post‐invasive resistance to an avirulent isolate of P. infestans, resulting in successful infection of the first attacked cells without induction of cell death. However, cell death was observed in the subsequently penetrated cells. Although we failed to detect phytoalexins and antifungal activity in the extract from wild‐type leaves, post‐invasive resistance to avirulent P. infestans was reduced in transgenic leaves. On the other hand, A. solani frequently penetrated epidermal cells of transgenic leaves and caused severe disease symptoms presumably from a deficiency in unidentified antifungal compounds. The contribution of antimicrobial components to resistance to penetration and later colonization may vary depending on the pathogen species, suggesting that sesquiterpene cyclase‐mediated compounds participate in pre‐invasive resistance to necrotrophic pathogen A. solani and post‐invasive resistance to hemibiotrophic pathogen P. infestans.
Morphological Measurement of Supracondylar Femur Based on Digital Technology in Chinese Han Population
Authors: Wang Lei , Tian Dong‐mu , Liu Xin , Zhang Jian‐feng , Zhao Li‐ming , He Xin , Hu Yong‐cheng 
Published: April 2019

ObjectiveRelatively few studies have reported on the morphology of the supracondylar femur, which is a fundamental factor affecting prosthetic reconstruction. The objectives of the present study were to measure the morphological parameters of the supracondylar femur, to classify the supracondylar femur, and to provide theoretical guidance for the development of distal femoral prostheses.MethodsThe study consisted of 82 patients of Han Chinese nationality in North China. There were 57 men and 25 women included in the study, with an average age of 50.9 years (range, 18–87 years). Effective CT data should include a range of more than 10 cm for the distal femur. CT data for the right distal supracondylar femurs was obtained from DICOM files. Results for the cancellous bone and marrow cavity were retained, and information for the cortical bone was erased to obtain information of the lumen. Measurements of the intracortical cavity have not been reported previously. Lumen models were reconstructed with Mimics 17.0 software. The surfaces of the lumen models were smoothed with Geomagic studio 12.0 software. Using the Solidworks 2014 software, we established a 3‐D coordinate system, where variables of the lumen were examined. Correlations between the various measurements were calculated.ResultsThe supracondylar region of the femur was divided into five levels, and the length, breadth, height, and angle values were measured at each level. There were strong correlations between the length indexes (transverse diameter [EF], medial anteroposterior diameter [AC], middle anteroposterior diameter [GH], and lateral anteroposterior diameter [BD]) and the volume index (V). There were also strong correlations among the length indicators (EF, AC, GH, and BD) in each layer. Angle γ was correlated with the lateral anteroposterior diameter (BD) at L2–L6 layers (r = −0.383, −0.385, −0.296, −0.258, −0.24; all P < 0.05) and with the height index (h) at L4–L6 layers (r = −0.244, −0.385, −0.506; all P < 0.05). The most representative parameters were the medial anteroposterior diameter (AC2R2 = 0.865; AC6R2 = 0.932), the coronal width ratio, and the sagittal width ratio with volume. The analysis found that the lumen shape of flower–top hat accounted for 81% at most.ConclusionsThe supracondylar femur has an asymmetrical structural area. The coronal plane is dominated by a flowerpot‐like morphology, and the sagittal plane is narrowest in the lateral 1/3 and resembles a top‐hat‐like morphology. Our results provide theoretical guidance for developing distal femoral prostheses and for their clinical application.
Comparison of Less Invasive Stabilization System Plate and Retrograde Intramedullary Nail in the Fixation of Femoral Supracondylar Fractures in the Elderly: A Biomechanical Study
Authors: Du Yu‐ren , Ma Jian‐xiong , Wang Shuo , Sun Lei , Wang Ying , Lu Bin , Bai Hao‐hao , Hu Yong‐cheng , Ma Xin‐long 
Published: April 2019

ObjectiveTo compare the biomechanical stabilities of less invasive stabilization system (LISS) plate and retrograde intramedullary nail (IMN) for the comminuted femoral supracondylar fracture fractures in the elderly.MethodsSixteen pairs of embalmed cadaver femurs were obtained to simulate a comminuted supracondylar femur fracture (AO/OTA33‐A3) gap model. All left‐side specimens were fixed with LISS plate, and retrograde IMN were applied to the right‐side specimens. All specimens were tested in torsional, axial and cyclic load mode on an Instron testing machine.ResultsThe mean torsional stiffness for LISS plate group was 34.1% greater than retrograde IMN group (2.90 vs. 1.91 Nm/degree, P = 0.002), but the mean axial stiffness was greater for the retrograde IMN (199.16 vs. 303.93 N/mm, P < 0.001). The total deformation of LISS plate caused by cyclic axial loading was greater than retrograde IMN (4.17 vs. 3.57 mm, P = 0.014). Significantly less mean irreversible deformation was detected in LISS plate than in retrograde IMN (1.64 vs. 1.69 mm, P = 0.699). Failure loads of the constructs were significantly different between the two groups (LISS plate: 2941±128 N; retrograde IMN: 4022±176 N, P < 0.001).ConclusionFor comminuted femoral supracondylar fractures in the elderly, the tested instruments can both maintain sufficient biomechanical stabilities, but retrograde IMN is superior to LISS plate in deformation of fracture site.
Addressing viral and bacterial threats to salmon farming in Chile: historical contexts and perspectives for management and control
Authors: Figueroa Jaime , Cárcamo Juan , Yañez Alejandro , Olavarria Victor , Ruiz Pamela , Manríquez René , Muñoz Claudio , Romero Alex , Avendaño‐Herrera Ruben 
Published: April 2019

AbstractThe rapid growth of the salmon farming industry in Chile has led to the appearance of various viral, bacterial, parasitic, and fungal pathogens affecting farmed fish. The Chilean salmon industry has suffered several health crises associated with high fish mortalities, such as caused by the infectious salmon anaemia virus (2007) and harmful algal blooms (2016). In addition to these events, marine farms are continuously affected by outbreaks of harmful pathogens, including the bacteria Piscirickettsia salmonis and, most recently, a reappearance of Renibacterium salmoninarum, and the infectious pancreatic necrosis virus. These outbreaks have led to stricter regulations, but the salmon farming industry continues to struggle despite reforms. In addition to the aforementioned pathogens, which are a continuous threat, other apparently under control pathogens have also reappeared in recent years. In this review, we analyse the current state of knowledge on four of the main pathogens affecting salmon farming in Chile. The infectious pancreatic necrosis virus is relevant as it affects freshwater‐stage fish, with survivors then acting as carriers. The infectious salmon anaemia virus currently appears to be under control; however, P. salmonis and R. salmoninarum continue to be the cause for high mortalities in the Chilean aquaculture industry.
Conserved role for Ataxin‐2 in mediating endoplasmic reticulum dynamics
Authors: del Castillo Urko , Gnazzo Megan M. , Sorensen Turpin Christopher G. , Nguyen Ken C. Q. , Semaya Emily , Lam Yuwan , de Cruz Matthew A. , Bembenek Joshua N. , Hall David H. , Riggs Blake , Gelfand Vladimir I. , Skop Ahna R. 
Published: April 2019

AbstractAtaxin‐2, a conserved RNA‐binding protein, is implicated in the late‐onset neurodegenerative disease Spinocerebellar ataxia type‐2 (SCA2). SCA2 is characterized by shrunken dendritic arbors and torpedo‐like axons within the Purkinje neurons of the cerebellum. Torpedo‐like axons have been described to contain displaced endoplasmic reticulum (ER) in the periphery of the cell; however, the role of Ataxin‐2 in mediating ER function in SCA2 is unclear. We utilized the Caenorhabditis elegans and Drosophila homologs of Ataxin‐2 (ATX‐2 and DAtx2, respectively) to determine the role of Ataxin‐2 in ER function and dynamics in embryos and neurons. Loss of ATX‐2 and DAtx2 resulted in collapse of the ER in dividing embryonic cells and germline, and ultrastructure analysis revealed unique spherical stacks of ER in mature oocytes and fragmented and truncated ER tubules in the embryo. ATX‐2 and DAtx2 reside in puncta adjacent to the ER in both C. elegans and Drosophila embryos. Lastly, depletion of DAtx2 in cultured Drosophila neurons recapitulated the shrunken dendritic arbor phenotype of SCA2. ER morphology and dynamics were severely disrupted in these neurons. Taken together, we provide evidence that Ataxin‐2 plays an evolutionary conserved role in ER dynamics and morphology in C. elegans and Drosophila embryos during development and in fly neurons, suggesting a possible SCA2 disease mechanism.
The CT dorsolateral subluxation index is a feasible method for quantifying laxity in the feline hip joint
Authors: Valastro Carmela , Franchini Delia , Valentini Valerio , Lanave Gianvito , Maggiolino Aristide , Ciccarelli Stefano , Di Bello Antonio 
Published: April 2019

AbstractThe dorsolateral subluxation index of the femoral head is a good proxy of hip dysplasia in dogs. An exploratory, prospective, descriptive study was carried out in order to assess whether the dorsolateral subluxation index may also be useful to improve diagnosis of hip dysplasia in cats. The dorsolateral subluxation index was determined by CT scans simulating the loading position, and compared with measurements of the Norberg‐Olsson angle. A total of 82 cats were subjected to radiographic examination of the pelvis, in the standard ventro‐dorsal projection, and to CT scans of the pelvis and hips. The Norberg‐Olsson angle of each hip was calculated radiographically, while the dorsolateral subluxation index of the femur was calculated on CT images according to a technique recently developed for evaluation of hip dysplasia in dogs. Using the Norberg‐Olsson angle a total of 52 hips (31,7%) were diagnosed as dysplastic, 74 (45,1%) as non‐dysplastic, and 38 (23,1%) as borderline. Using the dorsolateral subluxation index, values ranged from a minimum of 34.6% to a maximum of 66.6% and four distribution classes were proposed. Findings indicated that the dorsolateral subluxation index previously described as method for quantifying hip dysplasia in dogs is also a feasible method for quantifying hip dysplasia in cats. Future studies are needed to more definitively determine the diagnostic sensitivity of this method.
Contaminant seeds in imported crop seed lots: a non‐negligible human‐mediated pathway for introduction of plant species to islands
Authors: Gervilla C , Rita J , Cursach J 
Published: April 2019

SummaryContaminant seeds in crop seed lots constitute a pathway for plant species introduction into new areas, and these non‐native weeds may be an environmental problem if they become invasive. Seed certification is a process that regulates and guarantees the quality of seed lots, including their purity. In this study, we assessed weed contamination in certified and non‐certified seed lots (n = 116) from 12 crop species commonly cultivated in the Balearic Islands. Contaminant seeds were separated using sieves, and then manually under a stereomicroscope, before they were germinated to confirm taxonomic identity. Weight, number and diversity of the contaminant seeds per kilogram of seed lot, number released per hectare according to sowing rate, and taxonomic identity and biogeographical origin of contaminant species were recorded. Although certification reduced the number of contaminant seeds in the seed lots, it did not entirely eliminate contaminants, because we found up to 2000 contaminant seeds kg−1 of certified ryegrass and sulla. Overall, contaminant seeds represented 118 taxa; of which, 82 were identified to species level, 70% of species were native, 19% were cultivated, and 11% were non‐native. Two of the identified taxa were first records for the Balearic Islands. In conclusion, contaminant seeds in imported crop seed lots represent a non‐negligible pathway for plant species introduction.
Development of a Novel Test Method to Characterize Material Properties in Corrosive Environments for Subsea HPHT Design
Authors: Thodla Ramgopal , Holtam Colum , Saraswat Rajil 
Published: April 2019

Abstract
High pressure high temperature (HPHT) design is a significant new challenge facing the subsea sector, particularly in the Gulf of Mexico. API 17TR8 provides HPHT Design Guidelines, specifically for subsea applications. Fatigue endurance (i.e., S–N) and fracture mechanics design are both permitted, depending on the criticality of the component. Both design approaches require material properties generated in corrosive environments, such as seawater with cathodic protection and/or sour production fluids. In particular, it is necessary to understand sensitivity to cyclic loading frequency (for both design approaches), crack growth rates (CGR) (for fracture mechanics approach) as well as fracture toughness performance. For many subsea components, the primary source of fatigue loading is associated with the start-up and subsequent shutdown operation of the well, with long hold periods in-between, during which static crack growth (CG) could occur. These are the two damage modes of most interest when performing a fracture mechanics based analysis. This paper presents the preliminary results of a novel single specimen test method that was developed to provide fatigue crack growth rate (FCGR) and fracture toughness data in corrosive environments, in a timeframe that is compatible with subsea HPHT development projects. Test data generated on alloy 625+ in seawater with cathodic protection are presented along with a description of how the test method was developed. A crack tip strain rate based formulation was applied to the data to rationalize the effect of frequency, stress intensity factor range (ΔK), and maximum stress intensity factor (Kmax).