bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENERAPAN FAMILY CENTERED-CARE (FCC) TERHADAP KETERAMPILAN ORANG TUA DALAM PERAWATAN BAYI PREMATUR
Authors: Yugistyowati Anafrin 
Published: March 2018

Background:Parents’ skillsin taking care of premature babies need to be developed to promote parents role in nurturing. The application of Family-Centered Care (FCC) through associated family program is one of the interventions to optimalize parent’s capability.
Objective:This study aimed to identify the parent’s skill in the care of premature baby before and after the
application of FCC.
Methods:The research design was quasi-experimental,employing pre- and post-test with nonequivalent control group. Data were collectedin a non-probability sample with consecutive sampling method. Sample wereparents who hadpremature babiesandwere hospitalized at Perinatology Unit Saras Husada Hospital Purworejo.This research involved 36 respondents. Data were analyzedwith the Wilcoxon Signed Ranks Test.
Result:There was not a significant difference on parents’ skills in control group (p= 0.083). Parents in intervention group showed difference in skills after the intervention (p= 0.025).
Conclusion: There were significant differences in parents’ skills, before and after the intervention of FCC.
Keywords:Premature Baby, Family-Centered Care, Skill Parents
STIGMA TERHADAP ORANG DENGAN GANGGUAN JIWA (ODGJ) PADA MAHASISWA PROGRAM STUDI ILMU KEPERAWATAN STIKES JENDERAL ACHMAD YANI YOGYAKARTA
Authors: Pamungkas Dewi Retno , Linawati One May , Sutarjo Puji 
Published: March 2018

Background: Stigma is a negative view of individuals that would have influences on how they feel about, and act upon others. Stigma towards people with mental health problems will negatively affect their recovery process. At a stage of their education, nursing students will meet with people with mental disorders. It is important to analyze their view towards people with mental disorders.
Objective: This research aimed to gain an overview on nursing students’ stigma towards people with mental disorders at Stikes Jenderal Achmad Yani Yogyakarta.
Methods: This study was descriptive quantitative with a cross sectional method and proportionate random sampling technique, involving 81 respondents. Data were obtained through a questionnaire. Students’ stigma was viewed from several aspects including education, gender, age and ethnicity. Stigma was assessed in three categories; low, moderate and high level of stigma.
Result: Result showed that within the categories, the highest prevalence was in the moderate level of stigma (96.3% or 78 people), high level of stigma accounted for 3.7% (3 people), and there was not respondent with low level of stigma.
Conclusion: The majority of nursing students at Stikes Jenderal Achmad Yani Yogyakarta had moderate
level of stigma. Keywords: stigma, mental disorder, nursing student
TINGKAT PENGETAHUAN TENTANG SEKS BEBAS PADA REMAJA KELAS XI DI SMA NEGERI 11 YOGYAKARTA TAHUN 2014
Authors: Suherni Suherni , Rahmawati Anita 
Published: March 2018

Background: Free sex has become more familiar to teenagers in today's life. This phenomenon occurs within many teenagers in junior and senior high schools, in big cities as well as in remote villages. Free sex may result in unwanted pregnancy, sexually transmitted infections, and social disruption in the society.
Objective: This study aimed to determine the level of knowledge about free sex in adolescents.
Methods: This research was conducted in April 2014, at SMA 11 Yogyakarta. The subjects were all students of class XI, consisted of 270 students. This study used a questionnaire as a measuring tool. Data analysis was performed with a univariate analysis.
Results: Results showed that most respondents had adequate level of knowledge (81%), 17% had moderate level of knowledge and 2% have low level of knowledge about free sex.
Conclusion: The level of knowledge about free sex in SMA Negeri 11 Yogyakarta students was majority adequate.
Keywords: Knowledge Level, Teens, Free Sex
HUBUNGAN PERAN SERTA KADER POSYANDU DENGAN PERAWATAN HIPERTENSI PADA LANJUT USIA (LANSIA) DI DESA SALAMREJO SENTOLO KULON PROGO
Authors: Sugiyanto Sugiyanto 
Published: March 2018

Background: One of the most prevalent cardiovascular problems in elderly people is hypertension.Health
cadres are those who voluntarily dedicate their time to have concern about elderly people’s health status in the community. Health cadres’ roles are important to promote elderly people quality of life, including their hypertension management.
Objectives: This research aimed to analyzethe correlation between the role of health cadres of elderly posyandu and the treatment of hypertension at Salamrejo Village Sentolo Kulon Progo.
Methods:This research was a correlational study with a cross sectional approach. The sample of this study was selectedwith a total sampling technique, drawn 57 hypertension patients. Data were analyzedwith Spearman rank correlation.
Results:The result showed that coefficient correlation value of Spearman’s rho (r) between the role of cadres of elderly posyandu and the treatment of hypertension patients was 0.294 and p-value was 0.026 (p< 0.05).
Conclusion:It can be concluded that there was a positive and significant correlation between the role of cadres of elderly posyandu and the treatment of hypertension.
Key word:cadres, elderly posyandu, hypertension
ANALISIS KUALITAS AIR MINUM DALAM KEMASAN (AMDK) DI YOGYAKARTA DITINJAU DARI PARAMETER FISIKA DAN KIMIA AIR
Authors: Aryani Titin 
Published: March 2018

Backgroud: Nowadays, bottled water has become the most substitute water for cooking drinking water. Although bottled water seemed attractive, it is crucial to assess its quality.
Objective: This quantitative study aimed to determine the quality of the 5 brands of bottled water circulating in Yogyakarta, in terms of physical parameters (temperature, smell, taste, color, turbidity, and TDS electroconductivity) and chemical parameters of water (pH, the presence of Cl-ions, and the presence of metals such as Cr, Fe, Zn, Cd).
Methods: The sampling technique used was purposive sampling. The instrument used to determine the quality of bottled water is the standard of drinking water quality standards.
Result: The results showed that five samples of bottled water circulating in Yogyakarta, are all qualified bottled water both in terms of physical parameters (temperature, smell, taste, color, turbidity, electroconductivity, and TDS) and chemical parameters of water (pH , the presence of Cl-ions, and the presence of metals such as Cr, Fe, Zn, Cd).
Conclusion: Five samples of bottled water circulating in Yogyakarta were suitable for consumption.
Keywords: Bottled water, water analysis, water quality, water chemistry parameters
Otorhinolaryngological Problem in Geriatric Population
Authors: Pyakurel Manita , Bhatta Rishi , Pokharel Rais 
Published: March 2018

Objective: The main objective of the study was to identify various geriatric otolaryngological problems in mid western part of Nepal.Materials and methods: A cross-sectional descriptive hospital based study was done from 1st January 2014 to 1st September 2014 among the all patients 60 years or above visiting the outpatient department of ENT/Emergency department of Nepalgunj Medical College. Data collection was done via interviewing with semi structured Performa with questionnaire. Data was entered in SPSS 17th version and exercised the analysis.Results: Among the total 866 geriatric population, female were 450 while 416 were male. Age ranged from 60 to 96 with average age of 70.3 years. Maximum numbers of elderly were of 60-70 years. Farming was the most common occupation in past. Sixty one percent (289) were smokers or tobacco chewer and 23% (106) consumed alcohol regularly. Majority of elderly had Hypertension as main co morbid condition. Decreased hearing was major complaint (82.6%) which was present for on an average 10.5years. Second leading ear problem was tinnitus (47.7%). Regarding nasal problems, bleeding nose was commonest (21.5%) followed by equal proportion of decreased smelling and nasal blockage (16%, 16.2%). Snoring was the frequent throat problem (58.4%) with average duration of approximately 6 years, followed by day time somnolence (16.6%).Conclusion: Among the ENT problems, hearing problem was the most common problem of these elderly. Nasal bleeding was common nasal problem presented among approximately one fourth of elderly. Among the throat problem snoring was the most prevailing with more than fifty percent occurrence. Occasional aesthetical complaint is very common. Head and neck malignancy was least common in these aged populationsNepalese Journal of ENT Head and Neck Surgery, Vol. 5, No. 2, 2014, Page: 23-25
Aerosol optical depth in the European Brewer Network
Authors: López-Solano Javier , Redondas Alberto , Carlund Thomas , Rodriguez-Franco Juan J. , Diémoz Henri , León-Luis Sergio F. , Hernández-Cruz Bentorey , Guirado-Fuentes Carmen , Kouremeti Natalia , Gröbner Julian , Kazadzis Stelios , Carreño Virgilio , Berjón Alberto , Santana-Díaz Daniel , Rodríguez-Valido Manuel , De Bock Veerle , Moreta Juan R. , Rimmer John , Smedley Andrew R. D. , Boulkelia Lamine , Jepsen Nis , Eriksen Paul , Bais Alkiviadis F. , Shirotov Vadim , Vilaplana José M. , Wilson Keith M. , Karppinen Tomi 
Published: March 2018

Abstract. Aerosols play an important role in key atmospheric processes and feature high
spatial and temporal variabilities. This has motivated scientific interest in
the development of networks capable of measuring aerosol properties over
large geographical areas in near-real time. In this work we present and
discuss results of an aerosol optical depth (AOD) algorithm applied to
instruments of the European Brewer Network. This network is comprised of
close to 50 Brewer spectrophotometers, mostly located in Europe and adjacent
areas, although instruments operating at, for example, South America and Australia are
also members. Although we only show results for instruments calibrated by the
Regional Brewer Calibration Center for Europe, the implementation of the AOD
algorithm described is intended to be used by the whole network in the
future. Using data from the Brewer intercomparison campaigns in the years
2013 and 2015, and the period in between, plus comparisons with Cimel
sun photometers and UVPFR instruments, we check the precision, stability, and
uncertainty of the Brewer AOD in the ultraviolet range from 300 to
320 nm. Our results show a precision better than 0.01, an uncertainty
of less than 0.05, and, for well-maintained instruments, a stability similar to that of the ozone measurements. We also discuss future improvements to our
algorithm with respect to the input data, their processing, and the
characterization of the Brewer instruments for the measurement of AOD.
Square wave voltammetry at carbon paste electrode modified with surfactant for alpha tocopheryl acetate determination in cosmetics
Authors: Žabčí­ková Simona , Nallbani Arlinda , Sýs Milan , Mikysek Tomáš , Červenka Libor 
Published: March 2018

The aim of this study was describe electrochemical properties of a carbon paste electrode (CPE) bulk modified with 30% (w/w) surfactant sodium dodecyl sulphate (CPE/SDS) and demonstrates its application in the determination of α‑tocopheryl acetate (α‑TAc), known as vitamin E acetate, in selected cosmetic products, especially body creams. In addition to anionic SDS, cationic hexadecylpyridinium chloride monohydrate (CPC) was also tested as possible modifier. It was found that selection of surfactant type and its content significantly affect an electrical conductivity and mechanical stability of these heterogeneous electroanalytical sensors in pure organic solvents. Under this study, it was found that CPC is a totally inappropriate mediator due to very high backgroundcurrent. Together with other lipophilic vitamins characterized by antioxidant activity (dominantly retionoids), this completely synthetic substance is widely used as significant cosmetic additive due its preservative properties. Monitoring of its content in cosmetic products is usually performed by high‑performance liquid chromatography (HPLC) with UV detection. This standard analytical protocol is always burdened with the complex and time‑consuming preparation of the sample before analysis. For that reason, robust and simple electroanalytical method based on anodic oxidation of the α‑TAc at CPE/SDS by square wave voltammetry (SWV) performed in pure organic electrolyte (99.8% acetonitrile containing 0.1 mol·L‑1 LiClO4) was developed. Moreover, simple dissolution of sample in supporting electrolyte using ultrasonic bath and subsequent filtering through a stacked filter included all the necessary procedures for sample preparation. The linear range from 0.1 to 1.2 mmol·L‑1and limit of detection 37 µmol·L‑1 were found at pulse amplitude 10 mV and frequency 10 Hz as optimum. In analysis of selected cosmetics, the developed electroanalytical method was not validated using comparison with standard HPLC. At least, the recovery was verified by analysis of model sample and value 95.8% was calculated.
A thaumatin-like genomic sequence identification in Vitis vinifera l., stormy wines and musts based on direct pcr
Authors: Žiarovská Jana , Zeleňáková Lucia , Kačániová Miroslava , Cusimamani Eloy Fernández 
Published: March 2018

Direct polymerase chain reaction method was use to amplify a thaumatin-like sequence of Vitis vinifera L. in grapes as well as in stormy wines and musts. Thaumatin-like proteins (TLPs) of Vitis vinifera possess beside its function in abiotic and biotic stress response another one - they are able to cause protein haze in wine unless removed prior to bottling. Direct PCR is an approach where omission of DNA extraction is typical prior the amplification of the target site of plant genome. Crude extract or small pieces of plant tissues are used in the analysis directly without steps of extraction and purification of gDNA. The biological material that was used in analysis was collected during August - October 2017 in local stores and winery Sabo and comprises from cultivars Iršai, Muškát, Savignon Blanc, Svätovavrinecké, Dornfelder and Pálava. Direct PCR was performed by a cutted piece of grape tissue and a dilution buffer was use in 1:2 for stormy wine or must, respectively. Direct amplification of thaumatin-like protein sequence of Vitis vinifera was performed along with the control reactions with the primers for conserved region of plant chloroplast. Possitive amplification of thaumatin-like allergen sequence resulted in 570 bp amplicon. The most abundant amplicons were amplified in stormy wines, followed by musts and the amplicons from grapes were weaker when comparing them to others. The amplicon specificity checking of obtained PCR product of thaumatin-like allergen was performed by restriction cleavage by Psi I and resulted in restriction amplicons of the 80 bp, 81 bp, 94 bp and 315 bp in length. Confirmation of the amplicon specificity by restriction cleavage support the potential of direct PCR to become a reproducible method that will be fully applicable in routine analysis of not only plant genomes in the future, but it was demonstrated, that it works in liquids, too.
Impact of Clinical Information on Melanocytic Skin Lesion Pathology Diagnosis
Authors: Lai Belinda , Soyer H. Peter , Zhu Lin , Ferguson Peter M. , O’Brien Blake , Dodds Tristan , Scolyer Richard A. , Ferrara Gerardo , Argenziano Giuseppe , Bell Katy J. L. 
Published: October 2024

ImportanceThere is poor accuracy and reproducibility for the histopathologic diagnosis of melanocytic skin lesions, and the provision of clinical information may improve this.ObjectiveTo examine the impact of clinical information on the histopathologic diagnosis of melanocytic skin lesions.Evidence ReviewPubMed, Embase, and Cochrane Library were searched for new records published from January 2018 to January 2024. References included in the 2018 Cancer Council Australia evidence review were also screened, and forward and backward citation searches were conducted.FindingsFrom 2224 records screened, 162 full-text studies were assessed, and 7 studies were included. Studies included pathologists from Austria, Germany, the US, Italy, the UK, and Australia. Patient populations had a mean age of 43 to 55 years and a proportion of female participants of 23% to 63%. The risk of bias assessment demonstrated that all studies had domains at unclear or high risk of bias. Clinical images increased diagnostic certainty (3 studies) and agreement between pathologists (2 studies) led to diagnostic upgrades in 7.6% to 16.7% of interpretations. Clinical diagnosis on the pathology requisition form reduced the odds of missing a melanoma with progression (1 study), while more clinical elements on the form correlated with higher re-excision rates (1 study). Among patients with distant metastases on long-term follow-up, a prior consensus diagnosis of melanoma was established on histopathology alone.Conclusions and RelevanceProviding clinical information to pathologists may improve diagnostic confidence and interobserver agreement and result in upgrading of the histopathologic diagnosis. While providing the clinical diagnosis may prevent missing a progressive melanoma, more research is needed to determine the appropriateness of histopathology upgrading when clinical images are provided and the impacts on patient outcomes.
Inflammation Promotes Aging‐Associated Oncogenesis in the Lung
Authors: Pham‐Danis Catherine , Chia Shi B. , Scarborough Hannah A. , Danis Etienne , Nemkov Travis , Zaberezhnyy Vadym , Christenson Jessica L. , Kleczko Emily K. , Navarro Andre , Goodspeed Andrew , Bonney Elizabeth A. , Dinarello Charles A. , Marchetti Carlo , Nemenoff Raphael A. , Hansen Kirk C. , DeGregori James 
Published: October 2024

ABSTRACTBackgroundLung cancer is the leading cause of cancer death in the world. While cigarette smoking is the major preventable factor for cancers in general and lung cancer in particular, old age is also a major risk factor. Aging‐related chronic, low‐level inflammation, termed inflammaging, has been widely documented; however, it remains unclear how inflammaging contributes to increased lung cancer incidence.AimThe aim of this study was to establish connections between aging‐associated changes in the lungs and cancer risk.MethodsWe analyzed public databases of gene expression for normal and cancerous human lungs and used mouse models to understand which changes were dependent on inflammation, as well as to assess the impact on oncogenesis.ResultsAnalyses of GTEx and TCGA databases comparing gene expression profiles from normal lungs, lung adenocarcinoma, and lung squamous cell carcinoma of subjects across age groups revealed upregulated pathways such as inflammatory response, TNFA signaling via NFκB, and interferon‐gamma response. Similar pathways were identified comparing the gene expression profiles of young and old mouse lungs. Transgenic expression of alpha 1 antitrypsin (AAT) partially reverses increases in markers of aging‐associated inflammation and immune deregulation. Using an orthotopic model of lung cancer using cells derived from EML4‐ALK fusion‐induced adenomas, we demonstrated an increased tumor outgrowth in lungs of old mice while NLRP3 knockout in old mice decreased tumor volumes, suggesting that inflammation contributes to increased lung cancer development in aging organisms.ConclusionsThese studies reveal how expression of an anti‐inflammatory mediator (AAT) can reduce some but not all aging‐associated changes in mRNA and protein expression in the lungs. We further show that aging is associated with increased tumor outgrowth in the lungs, which may relate to an increased inflammatory microenvironment.
Developing Lightweight Silanized Cellulose Ultramaterials as the Strongest Engineered Aerogel
Authors: Zhang Kangkang , Li Changzhao , Liu Lin , Wang Xian , Li Ning , Yang Chunwang , Huang Yuxi , Lu Hao , Liu Hejin , Li Jun , Qiu Jian , Yang Yushan 
Published: October 2024

AbstractSilica aerogel materials exhibit exceptional properties, including unique light, heat, fluid, and ion characteristics with vast potential. Despite similarities in composition to glass, silica aerogel lacks ductility and is prone to breakage upon impact. Therefore, the development of advanced engineering aerogel ultra materials that combine the mechanical strength of engineered materials with the ultralight superinsulation of aerogels remains a significant challenge. Herein, a multidimensional and multiscale gradient‐pore strategy is proposed for the scalable production of nanostructured silanized cellulose (SiCell) nanofibrous frameworks through colloidal self‐assembly using an active earth‐abundant biopolymer from the wood as a functional component. The configuration of the SiCell/polymer‐crosslinked silica‐aerogel‐powder (SiAP)‐locked structure creates a regional framework that forms SiCell/polymer‐crosslinked SiAP‐locked aerogels (SiCSiPA) with a 3D nanoporous architecture. With an ultralow thermal conductivity of 15.9 mW m−1 K−1, the lightweight super insulating SiCSiPA emerges as a prime candidate for thermal insulation, offering exceptional strength for practical applications. Moreover, SiCSiPA exhibits superior strength, stiffness, and toughness, making it the best insulating material. Owing to its outstanding strength‐to‐weight ratio and robust thermomechanical stability, SiCSiPA introduces a new technology for lightweight construction applications requiring superior thermal insulation.
Exos‐Loaded Gox‐Modified Smart‐Response Self‐Healing Hydrogel Improves the Microenvironment and Promotes Wound Healing in Diabetic Wounds
Authors: Yang Pu , Ju Yikun , Shen Naisi , Zhu Shuai , He Jiaqian , Yang Lingxiu , Lei Jiajie , He Xiaoli , Shao Wenjia , Lei Lanjie , Fang Bairong 
Published: October 2024

AbstractWound management has always been a challenge in the clinical treatment of diabetes. In this study, glucose oxidase (GOx) is grafted onto natural pullulan polysaccharides, and oxidization is carried out to form a self‐healing hydrogel using carboxymethyl chitosan by means of reversible Schiff base covalent bonding. The smart‐response drug release properties of this natural self‐healing hydrogel are demonstrated in diabetic wounds by taking advantage of two key factors, namely the pH‐responsive nature of Schiff base bonding and the fact that GOx reduces the pH in diabetic wounds. To further enhance the biological functions of the hydrogel dressing, exosomes (Exos) are introduced into the hydrogel system. The GOx present in the hydrogel system improves the high‐glucose microenvironment of diabetic wounds, releasing H2O2 to impart antimicrobial effects, and ensuring that the hydrogel realizes a smart‐response function. The carboxymethyl chitosan component used to construct the hydrogel plays an effective antibacterial role. Moreover, the Exos loaded into the hydrogel effectively promotes neovascularization of the wound. The Exos also regulates macrophage polarization and reduces the levels of persistent inflammation in diabetic wounds. These results suggest that this smart responsive, multifunctional, and self‐healing hydrogel dressing is ideal for the management of diabetic wounds.