bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypertension among adolescents in Nigeria: a retrospective study of adolescent university freshmen
Authors: Abiodun Olumide , Ladele Akindele , Olu-Abiodun Oluwatosin , Ashipa Temitope 
Published: March 2019

Abstract

Purpose
The burden of hypertension is rising both globally and in Africa specifically. We determined the prevalence of hypertension and the risk factors for clinical hypertension in a population of new university intakes over a 4-year period.

Methods
We analyzed retrospectively, the records of 6980 older adolescents (15–19 years). We used population-specific metrics to categorize blood pressure (BP) based on the 2017 Clinical Practice Guidelines by the American Academy of Pediatrics.

Results
The overall prevalence of high BP in our study was 25.1% [95% confidence interval (CI) 24.1–26.2] for elevated BP, 19.8% (95% CI 18.9–20.8) for stage 1 hypertension, and 5.5% (95% CI 5.0–6.1) for stage 2 hypertension. The prevalence of stage 2 hypertension was 8.7% (7.5–9.5) among the male participants and 3.2% (95% CI 2.7–3.2) among the female participants (p < 0.001). The multivariate analyses demonstrated an increased risk of high levels of BP (p < 0.001) with age (1.21: 95% CI 1.16–1.26), waist-to-height ratio (WHtR) (1.05: 95% CI 1.04–1.05), z-score for body mass index (BMI) (1.47: 95% CI 1.41–1.54), and hemoglobin concentration (1.10: 95% CI 1.09–1.12). It demonstrated a reduced risk of high levels of BP (p < 0.001) being female (0.35: 95% CI 0.32–0.39).

Conclusions
Hypertension, its risk factors and the risk of cardiovascular diseases in later life are prevalent in our Nigerian adolescent population. There is, therefore, a need for the development, evaluation and implementation of context-appropriate strategies and interventions to mitigate the risk of hypertension among adolescents, and cardiovascular diseases later in life.
Stability Analysis of a Mathematical Model for Glioma-Immune Interaction under Optimal Therapy
Authors: Khajanchi Subhas 
Published: March 2019

Abstract
We investigate a mathematical model using a system of coupled ordinary differential equations, which describes the interplay of malignant glioma cells, macrophages, glioma specific CD8+T cells and the immunotherapeutic drug Adoptive Cellular Immunotherapy (ACI). To better understand under what circumstances the glioma cells can be eliminated, we employ the theory of optimal control. We investigate the dynamics of the system by observing biologically feasible equilibrium points and their stability analysis before administration of the external therapy ACI. We solve an optimal control problem with an objective functional which minimizes the glioma cell burden as well as the side effects of the treatment. We characterize our optimal control in terms of the solutions to the optimality system, in which the state system coupled with the adjoint system. Our model simulation demonstrates that the strength of treatment

u

1

(
t
)

$u_{1}(t)$

plays an important role to eliminate the glioma cells. Finally, we derive an optimal treatment strategy and then solve it numerically.
Crystal structure of 2,4-pentanedione bis(2,4-dinitrophenylhydrazone), C17H16N8O8
Authors: Akpan Ekemini D. , Zamisa Sizwe J. , Omondi Bernard 
Published: March 2019

Abstract
C17H16N8O8, orthorhombic, Pna21 (no. 33), a = 13.2406(3) Å, b = 21.0883(5) Å, c = 7.1364(2) Å, V = 1992.64(9) Å3, Z = 4, R
gt(F) = 0.0285, wR
ref(F
2) = 0.0802, T = 173(2) K.
(Z)-N-tert-butyl-1-(2-(3,5-dichlorobenzamido)phenyl) methanimine oxide, C18H18Cl2N2O2
Authors: Mi Xia , Zhang Jingyu , Yang Jing 
Published: March 2019

Abstract
C18H18Cl2N2O2, monoclinic, P21/n (no. 14), a = 8.5266(3) Å, b = 17.9521(7) Å, c = 11.8709(4) Å, β = 97.288(3)°, V = 1802.41(10) Å3, Z = 4, R
gt(F) = 0.0515, wR
ref(F
2) = 0.1497, T = 293(2) K.
Crystal structure of poly[aqua(μ2-5-methoxyisophthalato-κ2
O,O′:O′′)-(1,2-bis(imidazol-1′-yl)ethane-κ2
N:N′)cobalt(II), C34H36Co2N8O12
Authors: Ling Xun-Li , Wei Yue-Min , Zhang Bi-Gang , Han Min-Le 
Published: March 2019

Abstract
C34H36Co2N8O12, triclinic, P1̄ (no. 2), a = 8.5834(8) Å, b = 10.2975(10) Å, c = 22.727(2) Å, α = 78.325(1)°, β = 82.934(1)°, γ = 69.214(1)°, V = 1836.3(3) Å3, Z = 2, R
gt(F) = 0.0319, wR
ref(F
2) = 0.0761, T = 296 K.
Crystal structure of 3-(5-amino-1H-1,2,4-triazol-3-yl)-1-(piperidin-1-yl)propan-1-one, C10H17N5O
Authors: Tan Lin Yuing , Lim Felicia Phei Lin , Dolzhenko Anton V. , Tiekink Edward R.T. 
Published: March 2019

Abstract
[C10H17N5O], monoclinic, P21/c (no. 14), a = 8.12150(10) Å, b = 13.2833(2) Å, c = 11.0258(2) Å, β = 110.083(2)°, V = 1117.14(3) Å3, Z = 4, R
gt(F) = 0.0311, wR
ref(F
2) = 0.0790, T = 100(2) K.
The influence of laccase/histidine system on the properties of OCC pulp fibers, and of handsheets made thereof
Authors: Chen Yangmei , Mai Yiqian , Wu Qitang , Kang Jiaqian , Jiang Yu , Mai Wanqi , Wei Zebin 
Published: March 2019

Abstract
For improving the physical properties of old corrugated container (OCC) fiber, the laccase/histidine system was used in this paper. Firstly, the paper studied the optimum conditions that the laccase/histidine system modified the OCC fiber, including enzyme dosage, histidine dosage, reaction time, reaction temperature, and pH. Experimental results showed that the optimum reaction conditions of laccase/histidine system for OCC pulp were: dose of enzyme 1 U·

g

−
1

{\text{g}^{-1}}

, 4 h reaction time, pH 4.5, dose of histidine 1 %. Under the optimum reaction conditions, the tensile and burst indexes of the sheet made from laccase/histidine treatment were increased by 25.2 % and 34.0 %, compared with that of the control sample. The SEM results showed that compared with the control sample, the fibrillation of the fiber modified with laccase/histidine was more obvious. Finally, the content of acid-insoluble lignin of the fiber was determined. The content of acid-insoluble lignin of the control sample was 29.2 %, and the content of acid-insoluble lignin of the fiber treated by laccase/histidine system in optimum reaction conditions was 16.0 %, which decreased by 13.2 %. Laccase/histidine system could improve the physical properties of recycled fiber, alleviate fiber decay, which are of great significance to solve the resource shortage and environment pollution of the paper-making industry.
Separation of trivalent actinides and lanthanides using various ‘N’, ‘S’ and mixed ‘N,O’ donor ligands: a review
Authors: Bhattacharyya Arunasis , Mohapatra Prasanta K. 
Published: March 2019

Abstract
Separation of trivalent actinide (An) and lanthanide (Ln) elements is one of the burning topics in the back end of the nuclear fuel cycle due to the similarity in their chemical behaviour. A significant amount of research is being carried out worldwide to develop suitable ligands for the separation of the trivalent actinides and lanthanides. Some of the research groups are engaged in continuous improvement of the di-ethylene-triamine-penta acetic acid (DTPA) based Ln/An separation method, whereas extensive research is going on for the development of the lipophilic and hydrophilic ‘N’ donor heteropolycyclic ligands as the actinide selective ligand. A number of ‘S’ donor ligands are also explored for the Ln/An separation. In the present review, we made an attempt to highlight various separation processes based on soft donor ligands developed for Ln/An separations. Beside the conventional solvent extraction processes, separation possibilities membrane based and solid phase extraction techniques are evaluated for the Ln/An separation and are compiled in the present review.
Representation of Haltere Oscillations and Integration with Visual Inputs in the Fly Central Complex
Authors: Kathman Nicholas D. , Fox Jessica L. 
Published: March 2019

The reduced hindwings of flies, known as halteres, are specialized mechanosensory organs that detect body rotations during flight. Primary afferents of the haltere encode its oscillation frequency linearly over a wide bandwidth and with precise phase-dependent spiking. However, it is not currently known whether information from haltere primary afferent neurons is sent to higher brain centers where sensory information about body position could be used in decision making, or whether precise spike timing is useful beyond the peripheral circuits that drive wing movements. We show that in cells in the central brain, the timing and rates of neural spiking can be modulated by sensory input from experimental haltere movements (driven by a servomotor). Using multichannel extracellular recording in restrained flesh flies (Sarcophaga bullataof both sexes), we examined responses of central complex cells to a range of haltere oscillation frequencies alone, and in combination with visual motion speeds and directions. Haltere-responsive units fell into multiple response classes, including those responding to any haltere motion and others with firing rates linearly related to the haltere frequency. Cells with multisensory responses showed higher firing rates than the sum of the unisensory responses at higher haltere frequencies. They also maintained visual properties, such as directional selectivity, while increasing response gain nonlinearly with haltere frequency. Although haltere inputs have been described extensively in the context of rapid locomotion control, we find haltere sensory information in a brain region known to be involved in slower, higher-order behaviors, such as navigation.SIGNIFICANCE STATEMENTMany animals use vision for navigation; however, these cues must be interpreted in the context of the body's position. In mammalian brains, hippocampal cells combine visual and vestibular information to encode head direction. A region of the arthropod brain, known as the central complex (CX), similarly encodes heading information, but it is unknown whether proprioceptive information is integrated here as well. We show that CX neurons respond to input from halteres, specialized proprioceptors in flies that detect body rotations. These neurons also respond to visual input, providing one of the few examples of multiple sensory modalities represented in individual CX cells. Haltere stimulation modifies neural responses to visual signals, providing a mechanism for integrating vision with proprioception.
A rare cause of postpartum acute hyponatremia
Authors: Rahmani Tzvi-Ran Ilan , Olchowski Judith , Fraenkel Merav , Bashiri Asher , Barski Leonid 
Published: March 2019

Summary
A previously healthy 24-year-old female underwent an emergent caesarean section without a major bleeding described. During the first post-operative days (POD) she complained of fatigue, headache and a failure to lactate with no specific and conclusive findings on head CT. On the following days, fever rose with a suspicion of an obstetric surgery-related infection, again with no evidence to support the diagnosis. On POD5 a new-onset hyponatremia was documented. The urine analysis suggested SIADH, and following a treatment failure, further investigation was performed and demonstrated both central hypothyroidism and adrenal insufficiency. The patient was immediately treated with hydrocortisone followed by levothyroxine with a rapid resolution of symptoms and hyponatremia. Further laboratory investigation demonstrated anterior hypopituitarism. The main differential diagnosis was Sheehan’s syndrome vs lymphocytic hypophysitis. Brain MRI was performed as soon as it was available and findings consistent with Sheehan’s syndrome confirmed the diagnosis. Lifelong hormonal replacement therapy was initiated. Further complaints on polyuria and polydipsia have led to a water deprivation testing and the diagnosis of partial central insipidus and appropriate treatment with DDAVP.

Learning points:

Sheehan’s syndrome can occur, though rarely, without an obvious major post-partum hemorrhage.

The syndrome may resemble lymphocytic hypophysitis clinically and imaging studies may be crucial in order to differentiate both conditions.

Hypopituitarism presentation may be variable and depends on the specific hormone deficit.

Euvolemic hyponatremia workup must include thyroid function test and 08:00 AM cortisol levels.
Урбанонимы в украинском и английском сленге: к вопросу об эквивалентности в переводе
Authors: Бондаренко Екатерина 
Published: March 2019

[full article and abstract in Russian; abstract in English]
This article investigates the informal verbalizations of urban place names; it also questions the hypothesis of their potential untranslatability. The concept of slang is based on the assumption that slang acts as a linguistic channel for liberating carnivalesque laughter. The most numerous lexical fields (presumably most important for the carnivalesque worldview) are those denoting entertainment establishments (brothels, night clubs, cafes), prisons and hospitals. Humankind resorts to substandard communication to state the predominance of primeval instincts, a negative relation to the dominant value system with its restrictions. Mocking values and norms, physiological deficiency, gender or racial peculiarities is the essence of slang as a constituent of humour culture. Slang is a revolt against hierarchy. It relieves tension without endangering the stability of the society. Lexical semantic analysis of slang toponyms shows the potential possibility of adequate comparing and translating of place names in both directions.
Raganos ir burtininkai lietuvių mitologinėse sakmėse ir jų atitikmenys rusų ir anglų kalbose
Authors: Gimževskienė Karolina 
Published: March 2019

[full article and abstract in Lithuanian; abstract in English]
This article aims to find cultural equivalents for a group of Lithuanian mythological creatures, namely, magical people, including wizards, witches, sorcerers, etc. in English and Russian languages. Therefore, first, different sources of folkloric translation and its specific issues were consulted, which created the possibility for discussion of some cultural aspects as well as links between Lithuanian, Slavic and Celtic folklore. Second, a comparative analysis of the named mythological creatures in Lithuanian, Russian and English languages and cultures was carried out. The results of the analysis have shown which names of these creatures might be considered exact cultural equivalents and which of them are only partial analogs. Such information is useful not only when choosing a domestication strategy, but for a foreignization strategy as well because these equivalents can be used both in the translation text itself and in additional extratextual comments.
The conclusions given at the end of this article and the provided table, where specific translation suggestions are given, may be of practical importance for translators or authors writing about Lithuanian mythology and folklore for English or Russian speaking readers.
Impacto da autopercepção de saúde em longevos com incontinência urinária
Authors: Jorge Luisa Braga , Neves Bruna Borba , Rocha Josemara De Paula , Ulrich Vivian , Bós Ângelo José Gonçalves 
Published: March 2019

AIMS: To verify the impact of self-perceived health on the chance of developing urinary incontinence in very-old.METHODS: This is a cross-sectional and analytical study with elderly individuals aged 90 years and over. The statistical and analytical variables (sex, marital status, continence, age, depressive symptoms, cognition, comorbidities and ability to perform activities) were analyzed analytical and descriptive statistics (frequencies, mean and standard deviation, univariate and health self-perception adjusted logistic regression analysis).RESULTS: There were 182 participants, 71% women. The previous diagnosis of depression, the score of depressive symptoms and the percentage of ease for functional and basic activities were related to self-perception of health (p<0.05). The loss of urine, however, was not related to self-perceived health. The self-perception of health influenced the effect of the variables previous diagnosis of depression, number of depressive symptoms, Mini-Mental State Examination score and number of comorbidities on the chance of urinary incontinence in thepresence of these variables. Males, widowhood and ease of performance of basic and functional activities were significantly related to urinary incontinence regardless of the adjustment of health self-perception.CONCLUSIONS: There was no relationship between urinary incontinence and health self-perception. However, health self-perception influenced the effect of sociodemographic and clinical variables on the chance of having urinary incontinence.
Inhibition of Serotonin Synthesis May Have Antitumor Activity? Long-Term Efficacy in a Patient with Gastrointestinal Neuroendocrine Tumor
Authors: Molina-Cerrillo Javier , Grande Enrique , Alonso-Gordoa Teresa 
Published: March 2019

Abstract
In this article, we propose, based on a clinical case, the potential antitumor effect related to the inhibition of serotonin in neuroendocrine tumors (NETs). Currently, the only drug that exists for the symptomatic treatment of carcinoid syndrome refractory to somatostatin analogues is telotristat, based on its pivotal study, the TELESTAR trial. Based on the existing preclinical rationale, it seems that the inhibition of serotonin may have an antitumoral role in NETs. Briefly, serotonin may act as an autocrine growth factor of NETs, and it may also play an immunomodulatory role by enhancing macrophage polarization to an immunotolerant M2 phenotype. To our knowledge, this rationale for the possible antitumor effect of serotonin in NETs has not yet been published in the literature.
İLKÖĞRETİM MATEMATİK ÖĞRETMEN ADAYLARININ HAFIZA OYUNLARI İLE HAFIZA OYUNLARININ MATEMATİK ÖĞRETİMİNE KATKISINA İLİŞKİN GÖRÜŞLERİ
Authors: SAYGI Elif , ALKAŞ ULUSOY Çiğdem 
Published: March 2019

Bu makalenin amacı ilköğretim matematik öğretmen adaylarının zeka
oyunu türlerinden hafıza oyunları ve hafıza oyunlarının matematik öğretimine
katkısı hakkındaki düşüncelerini incelemektir. Bu amaçla 2017-2018 öğretim
yılında Ankara ilindeki bir devlet üniversitesinde Matematik Eğitimi Anabilim
Dalı-İlköğretim Matematik Öğretmenliği Programına devam eden 39 öğretmen
adayının görüşüne başvurulmuştur. İlköğretim
matematik öğretmen adaylarının hafıza oyunları ile ilgili görüşleri
araştırmacılar tarafından geliştirilen bir ölçme aracı ile toplanmıştır. Ölçme
aracı, hafıza oyunu türünde oynanan her oyundan sonra uygulanmak üzere,
öğrencilerin o oyunla ilgili düşüncelerini yansıtacakları, dört açık uçlu
sorudan oluşan bir yansıtıcı düşünme formu (reflection form) şeklinde
düzenlenmiştir. Çalışmada ulaşılan bulgular sonucunda öğretmen adaylarının
hafıza oyunlarını orta düzeyde zor bulduklarını ifade ettikleri görülmüştür.
Öğretmen adayları oyunlarda zorlanıp zorlanmama durumlarını; harcanan zaman,
hatırlanması gereken şeylerin sayısı ve çeşitliliği, oyuna uygun bir örüntü
veya strateji yaratılabilmesi, hatırlanacak sayı, şekil veya nesneye bir
manipülasyon yapılıp yapılmaması, bireysel inançlar gibi kriterlerle
değerlendirmişlerdir. Öğretmen adayları ayrıca hafıza oyunlarında birçok
matematiksel fikri aynı anda kullanabildiklerini, tek bir oyun içinde birden
fazla matematiksel becerinin geliştirilebileceğini de vurgulamışlardır.
Öğretmen adaylarının hafıza oyunlarının matematik öğretimine katkısı ile ilgili
fikirleri matematiksel becerilerin gelişiminin sağlanması, matematiksel
kavramların anlamlı öğrenilmesi, kavramların doğru yerde ve doğru şekilde
kullanılması, farklı stratejilerin öğretimi, motivasyonu yüksek bir sınıf
kültürü yaratılması, odaklanma, düşünme ve hafızada tutmaya katkı sağlama,
zaman kontrolü ve hızlı düşünmeyi geliştirme gibi temalarla özetlenmiştir.
AKILCI DUYGUSAL DAVRANIŞÇI TERAPİYE DAYALI PSİKO-EĞİTİM PROGRAMININ İLKOKUL ÖĞRENCİLERİNİN SALDIRGANLIK DÜZEYLERİNE ETKİSİ
Authors: ÇEKİÇ Ali , BUĞA Ahmet , KUL Aykut , ŞAP Gülsüm 
Published: March 2019

Bu araştırmada,&nbsp;
Akılcı-Duygusal-Davranışçı Terapiye (ADDT) dayalı psiko-eğitim
programının çocukların saldırganlık düzeylerine etkisi incelenmiştir.
Araştırmada ön test, son test ölçümlü yarı deneysel desen kullanılmıştır.
Çalışma grubu ilkokul üçüncü ve dördüncü sınıfta öğrenimlerine devam eden
Saldırganlık Ölçeği’nden (SÖ) ortalamanın bir standart sapma (ss=3,62)&nbsp; üzerinde puan alan öğrencilerden
oluşturulmuştur. Deney grubuna (n=8) dokuz oturumluk saldırgan davranışların
azaltılmasına yönelik bir psiko-eğitim uygulanırken, kontrol grubu (n=8) ile
herhangi bir çalışma yapılmamıştır. Araştırmadan elde edilen bulgulara göre
psiko-eğitim programının; çocukların saldırganlık düzeylerinin azalmasında, bir
anlamda öfkelerini kontrol etme ve saldırgan olmayan yollarla ifade etme
becerilerini kazandırmada etkili olduğu sonucuna ulaşılmıştır. Elde edilen bu
sonuçlar ilgili alan yazını destekler niteliktedir.
DRAMA YÖNTEMİNİN 7.SINIF ÖĞRENCİLERİNİN GÜNEŞ SİSTEMİ VE ÖTESİ: UZAY BİLMECESİ ÜNİTESİNDEKİ BAŞARILARINA ETKİSİ
Authors: ÇİRKİNOĞLU ŞEKERCİOĞLU Ayşe Gül , YILMAZ AKKUŞ Gamze 
Published: March 2019

Bu çalışmada, “Güneş Sistemi ve Ötesi: Uzay Bilmecesi” ünitesinin geleneksel
öğretim yöntemi ve drama yöntemi ile öğretimi yapılarak bu yöntemler
karşılaştırılmıştır. Çalışmaya 2014-2015 öğretim yılında Balıkesir ilindeki bir
devlet okulunda öğrenim gören 44 ortaokul 7. sınıf öğrencisi katılmıştır.
Çalışmada deneysel modellerden ön test, son test, kontrol gruplu yarı deneysel
desen kullanılmıştır. Veri toplama aracı olarak, Dünyamız ve Evren Başarı Testi
ile yarı yapılandırılmış görüşme soruları kullanılmıştır. Çalışma verilerinin
analizlerine göre Dünyamız ve Evren Başarı Testi puanlarının deney grubu lehine
istatistiksel olarak anlamlı düzeyde farklı olduğu bulunmuş ve drama yönteminin
öğrenci başarısını artırdığı tespit edilmiştir. Ayrıca drama yöntemiyle öğrenim gören erkek öğrencilerin son test
puanlarının kontrol grubundaki erkek öğrencilere göre anlamlı düzeyde arttığı belirlenmiştir.
STRATEGI PEMASARAN UNTUK MENINGKATKAN VOLUME PENJUALAN DI CAVINTON HOTEL YOGYAKARTA
Authors: Atmoko Temoteus Prasetyo Hadi 
Published: March 2019

ABSTRAKPembagunan hotel di Yogyakarta yang semakin banyak menyebabkan ketatnya persaingan industri perhotelan. Persaingan tersebut membuat manajemen harus memiliki stategi pemasaran agar dapat meningkatkan volume penjualan dari waktu ke waktu. Tujuan dari penelitian ini adalah mengetahui bagaimana strategi pemasaran untuk meningkatkan volume penjualan di Cavinton Hotel Yogyakarta. Penelitian ini menggunakan metode deskriptif kualitatif dengan analisis SWOT untuk memanfaatkan peluang dan memaksimalkan kekuatan, mengurangi kelemahan serta menghindari ancaman. Strategi S-O, S-T, W-O, dan W-T yang diterapkan untuk meningkatkan volume penjualan di Cavinton Hotel Yogyakarta yaitu dengan menambah fasilitas hotel berupa meeting room dan Malioboro sky lounge bar, mempromosikan produk makanan dan minuman sesuai dengan selera dan kebutuhan masyarakat, mengembangkan fasilitas untuk pendidikan berupa table manner dan cooking class, inovasi produk untuk event khusus keluarga, melalukan pemasaran melalui B2B dan B2C, memberikan tingkat harga yang kompetitif, serta pemberian training kepada karyawan.Kata Kunci: Strategi, Pemasaran, Volume Penjualan ABSTRACTThe establishment of the hotel in Yogyakarta grown up in numbers has increasingly led to tight competition in the hospitality industry. This competition generate management should have a marketing strategy in order to increase the sales volume from time to time. The purpose of this study is to find out how marketing strategies to increase the sales volume in Cavinton Hotel Yogyakarta. This research study uses a descriptive quantitative method and SWOT analysis to have advantage of opportunities and maximize strengths, reduce weaknesses and avoid threats. The strategy of S-O, S-T, W-O, and W-T applied to increase the sales volume in Cavinton Hotel Yogyakarta such as adding hotel facility of meeting room and Malioboro sky lounge bar, promoting food and beverage products according to the tastes and needs of the general public, developing facilities for education in the form of table manner and cooking class, product innovation for family special event, marketing through B2B and B2C, providing competitive price levels, and provision of training to the employees. Keywords: Strategy, Marketing, Sales Volume