bluuebunny/crossref_metadata_2025_split huggingface dataset:
Illumina and Nanopore methods for whole genome sequencing of hepatitis B virus (HBV)
Authors: McNaughton Anna L , Roberts Hannah E , Bonsall David , de Cesare Mariateresa , Mokaya Jolynne , Lumley Sheila F , Golubchik Tanya , Piazza Paolo , Martin Jacqueline B , de Lara Catherine , Brown Anthony , Ansari M Azim , Bowden Rory , Barnes Eleanor , Matthews Philippa C 
Published: November 2018

AbstractAdvancing interventions to tackle the huge global burden of hepatitis B virus (HBV) infection depends on improved insights into virus epidemiology, transmission, within-host diversity, drug resistance and pathogenesis, all of which can be facilitated by the large-scale generation of full-length virus genome data. Here we describe advances to a protocol to exploit the circular HBV genome structure, using isothermal rolling-circle amplification to enrich for HBV DNA and to generate concatemeric amplicons containing multiple successive copies of the same genome. We show that this product is suitable for Nanopore sequencing as single reads, as well as for generating short-read Illumina sequences. Nanopore reads can be used to implement a straightforward method for error correction that reduces the per-read error rate, by comparing multiple genome copies combined into a single concatemer and by comparing reads generated from plus and minus strands. Thus we can achieve improved consensus sequencing accuracy of 99.7% and resolve intra-sample sequence variants to form whole-genome haplotypes. The combination of isothermal amplification and Nanopore sequencing offers the longer-term potential to develop point-of-care tests for HBV, which could also be adapted for other viruses.
Dust or disease? Perceptions of influenza in rural Southern Malawi
Authors: Phiri Mackwellings , Gooding Kate , Peterson Ingrid , Mambule Ivan , Nundwe Spencer , McMorrow Meredith , Desmond Nicola 
Published: November 2018

AbstractBackgroundInfluenza virus infections cause between 291 243 and 645 832 deaths annually, with the highest burden in low-income settings. Research in high-income countries has examined public understanding of influenza, but there is little information on views and behaviours about influenza in low-income countries. We explored communities’ ideas about the severity, causes, prevention and treatment of influenza in Chikwawa district, Malawi.MethodsWe conducted 64 in-depth interviews with parents of children aged <5 years, and 7 focus groups with community health workers, parents, and traditional healers. Data were analysed thematically and using a framework matrix to compare views between groups.ResultsRespondents held varied ideas about influenza, and many were uncertain about its causes and treatment. Some parents, traditional healers and health workers thought influenza was not severe because they felt it did not cause death or limit activities, but others disagreed. Many saw influenza as a symptom of other conditions, especially malaria and pneumonia, rather than as a disease of its own. Most mentioned dust as the main cause of influenza and believed influenza could be prevented by cleaning the home thoroughly. Treatment seeking for influenza followed different stages, usually starting with home remedies followed by purchasing drugs from groceries and then visiting a health centre. Seeking a clinician tended to be triggered by severe symptoms like high fever or difficulty breathing, and suspicions of malaria or pneumonia. Community health workers provide health education for communities, but some lacked understanding of influenza.ConclusionOur findings suggest uncertainty about the causes and control of influenza among parents and varied levels of understanding among health providers. Strengthening the capacity of community health workers to provide relevant information about influenza prevention and treatment could address parents’ interest in further information and support informed health seeking and engagement with future influenza interventions.
Effect of simulated microgravity on gene expression during embryogenesis ofArabidopsis thaliana
Authors: Švécarová Michaela , Kovalová Markéta , Ondřej Vladan 
Published: November 2018

AbstractGravitational force is one of environmental factors that influence growth and development of plants. Changes in this force, including microgravity, can be one of the stress factor which plants have to adapt to cope with. That kind of stress can lead to several abnormalities such as chromosomal breakage, morphological abnormalities or changes in gene expression. The aim of this study was to examine the influence of simulated microgravity on gene expression ofArabidopsis thalianaembryos by use Random Positioning Machine (RPM). RPM is laboratory facility that can generate conditions comparable to the true microgravity. This paper studies effect of simulated microgravity on expression of genes which are involved in plant embryogenesis (LEAFY COTYLEDON, LATE EMBRYOGENESIS ABUNDANT), antioxidative system (CATALASE), mechanical stimuli (TOUCH) and gravitropism (SCARECROW, SHOOT GRAVITROPISM2). Changes in gene expression were detected using quantitative real-time PCR (qRT-PCR). Several of tested genes had increased transcript levels after the influence of simulated microgravity. Specifically, catalase (CAT3), LECs (LEC1), touch (TCH2/CML24), and gravitropism (SGR2) genes achieved significantly increased relative expression (level ≥ 2). The changes in the levels of expression on embryos ofArabidopsisdepend on the type of genes and principally on the timing of the influence of the simulated microgravity.
Prevalence of HIV risk behavior among male substance abusing offenders of intimate partner violence
Authors: Fernandes Camila , Berbary Cassandra , Crane Cory A. , Easton Caroline J. 
Published: November 2018

Purpose
The purpose of this paper is to assess the rates of HIV risk-taking behavior and sexual violence among clients with co-occurring addiction and intimate partner violence (IPV). The current study also aims to determine whether HIV risk-taking behaviors (e.g. trading sex for money or drugs, having unprotected sex with multiple partners) differ among substance using IPV offenders with and without a history of sexual aggression.

Design/methodology/approach
Secondary analyses were conducted from Easton et al.’s (2017) randomized controlled trial of substance use domestic violence treatment among substance using IPV offenders. Correlational analyses were conducted to assess the relationship between pre-treatment sexual aggression, HIV risk-taking behaviors, substance use and aggression. Analyses of covariance were conducted in order to determine differences in participants’ HIV risk-taking behaviors based on their history of sexual aggression while controlling for hours of contact with the female partners.

Findings
In a sample of 63 participants, males with higher rates of sexual aggression were more likely to engage in sexual risk-taking behaviors. This study encountered a correlation between pre-treatment risk-taking behavior and verbal and physical aggression, as well as a correlation between pre-treatment risk-taking behaviors and cocaine use. Results neither suggest a relationship between sexual aggression and alcohol use nor HIV risk-taking behaviors and alcohol use at pre-treatment.

Research limitations/implications
The present study is limited by sample size and power.

Originality/value
This study is among the first of its kind to investigate HIV risk-taking behaviors among substance using offenders of IPV. This study provides support for the inclusion of treatment targeting HIV risk-taking behaviors among IPV offenders.
Propulsion model for (hybrid) unmanned aircraft systems (UAS)
Authors: Dahms Julius , Bardenhagen Andreas 
Published: November 2018

Purpose
This paper deals with the estimation of the necessary masses of propulsion components for multirotor UAS. Originally, within the design process of multirotors, this is an iterative problem, as the propulsion masses contribute to the total takeoff mass. Hence, they influence themselves and cannot be directly calculated. The paper aims to estimate the needed propulsion masses with respect to the requested thrust because of payload, airframe weight and drag forces and with respect to the requested flight time.

Design/methodology/approach
Analogue to the well-established design synthesis of airplanes, statistical data of existing electrical motors, propellers and rechargeable batteries are evaluated and analyzed. Applying Rankine and Froude’s momentum theory and a generic model for electro motor efficiency factors on the statistical performance data provides correlations between requested performance and, therefore, needed propulsion masses. These correlations are evaluated and analyzed in the scope of buoyant-vertical-thrusted hybrid UAS.

Findings
This paper provides a generic mathematical propulsion model. For given payloads, airframe structure weights and a requested flight time, appropriate motor, propeller and battery masses can be modelled that will provide appropriate thrust to lift payload, airframe and the propulsion unit itself over a requested flight time.

Research limitations/implications
The model takes into account a number of motors of four and is valid for the category of nano and small UAS.

Practical implications
The presented propulsion model enables a full numerical design process for vertical thrusted UAS. Hence, it is the precondition for design optimization and more efficient UAS.

Originality/value
The propulsion model is unique and it is valid for pure multirotor as well as for hybrid UAS too.
Evaluating the effectiveness of corporate boards
Authors: Nordberg Donald , Booth Rebecca 
Published: November 2018

Purpose
This paper aims to examine how board evaluations have emerged as an important tool in public policy and corporate practice for enhancing board effectiveness.

Design/methodology/approach
The authors review the extensive literature on effectiveness and the emerging literature on board evaluation to identify ways to assess the current policy direction for external evaluation of corporate boards.

Findings
The paper develops an integrated framework of effectiveness that can be used as a tool for board evaluation, in particular for externally facilitated exercises.

Research limitations/implications
Through its integration of prior conceptual work this paper advances our theoretical understanding of this emerging part of policy and practice, with to-date lack much empirical basis.

Practical implications
The framework that is developed shows ways to focus how the practice is conducted by boards and external evaluators alike.

Social implications
It can also help policy formation by pointing out the limitations as well as benefits of various policy options.

Originality/value
In pointing to ways to develop study of the field through empirical research, it provides direction for future academic research. It also identifies a need for and direction toward the professionalization of practice.
Real-time implementation of MRAS rotor time constant estimation for induction motor vector control based on a new adaptation signal
Authors: Omari Aymen , Ismail Khalil Bousserhane , Hazzab Abdeldjebar , Bouchiba Bousmaha , Benmohamed Fayssal ElYamani 
Published: November 2018

PurposeThe major disadvantage of the field-oriented control (FOC) scheme of induction motors is its dependency on motor parameter variations because of the temperature rise. Among the motor parameters, rotor resistance is a parameter that can degrade the robustness of FOC scheme. An inaccurate setting of the rotor resistance in the slip frequency may result in undesirable cross coupling and performance degradation. To overcome this disadvantage, the purpose of this paper is to propose a model reference adaptive system (MRAS) rotor time constant tuning to improve the induction motor drive performance and to compensate the flux orientation error in vector control law.Design/methodology/approachFirst, the dynamic model and the indirect field-oriented control of induction motor are derived. Then, an inverse rotor time constant tuning is proposed based on MRAS theory where a new adaptation signal formulation is used as reference model, and the estimated stator currents obtained from induction motors (IM) state space resolution is used in the adaptive model.FindingsThe effectiveness and robustness of IM speed control with the proposed MRAS inverse rotor time constant estimator is verified through MATrix LABoratory/Simulink model simulation and laboratory experimental results. The simulation and experimental results show good transient drive performances, satisfactory for rotor resistance estimation and robustness with regard to uncertainties and load torque disturbance.Originality/valueThis paper presents an online tuning of the inverse rotor time constant using a new adaptation signal MRAS model. The proposed estimator is proved to guarantee the stability for different operating conditions, especially in very low/zero speed region and heavy load torque. The stability analysis of the proposed estimation procedure is also demonstrated.
Islamic finance: financial inclusion or migration?
Authors: Tahiri Jouti Ahmed 
Published: November 2018

Purpose
This paper aims to define a methodology to assess the impact of introducing Islamic finance on financial inclusion.

Design/methodology/approach
The paper is based on a literature review to understand the link between Islamic finance and financial inclusion. The second part of the paper presents a conceptual framework to assess the impact of introducing Islamic finance on financial inclusion in a defined context based on the profiling of people interested in Islamic finance.

Findings
The paper brings an insight on the impact of introducing Islamic finance. Indeed, it could cause a financial migration to Islamic banks that can take many forms and depends on many factors that call for deep analysis.

Research limitations/implications
The paper would help financial authorities and financial institutions to measure the impact of introducing Islamic finance on their businesses and the stability of the whole system.

Practical implications
Islamic finance can not only enhance financial inclusion but also create financial migration. The two implications can vary from one context to another.

Social implications
Islamic finance can contribute in the effort of including “self-excluded” people with religious concerns as well as people without access to financial services.

Originality/value
This paper promotes the idea that Islamic finance is not exclusively a way to enhance financial inclusion.
Symmetry influences packaging aesthetic evaluation and purchase intention
Authors: Bigoin-Gagnan Arnaud , Lacoste-Badie Sophie 
Published: November 2018

Purpose
The purpose of this paper is to examine the influence of the symmetrical disposition of information items displayed on the front of product packaging on perceived complexity, perceptual fluency, aesthetic evaluation and product purchase intention.

Design/methodology/approach
A sample of 104 participants was exposed to fast-moving consumer goods packaging. A within-subject design experiment was carried out to assess the influence of the symmetrical disposition of information items displayed on the front of the packaging. ANOVA and a PROCESS procedure to assess mediation (Hayes, 2013) examined the relationships among the factors influenced by symmetry.

Findings
This study found that the symmetrical disposition of information items around the vertical axis (mirror symmetry) decreased visual complexity and highlighted an “indirect-only mediation” of visual complexity on the aesthetic evaluation of the packaging through processing fluency. This research also highlighted the fact that packaging aesthetic evaluation had a positive influence on purchase intention.

Originality/value
This study extends knowledge on package design by showing that the elements on which the producer can act (in this case, symmetry on the front of packaging) have an influence on the consumer’s evaluation of the product and intention to purchase.
Learning analytics: where information science and the learning sciences meet
Authors: Teasley Stephanie Danell 
Published: November 2018

PurposeThe explosive growth in the number of digital tools utilized in everyday learning activities generates data at an unprecedented scale, providing exciting challenges that cross scholarly communities. This paper aims to provide an overview of learning analytics (LA) with the aim of helping members of the information and learning sciences communities understand how educational Big Data is relevant to their research agendas and how they can contribute to this growing new field.Design/methodology/approachHighlighting shared values and issues illustrates why LA is the perfect meeting ground for information and the learning sciences, and suggests how by working together effective LA tools can be designed to innovate education.FindingsAnalytics-driven performance dashboards are offered as a specific example of one research area where information and learning scientists can make a significant contribution to LA research. Recent reviews of existing dashboard studies point to a dearth of evaluation with regard to either theory or outcomes. Here, the relevant expertise from researchers in both the learning sciences and information science is offered as an important opportunity to improve the design and evaluation of student-facing dashboards.Originality/valueThis paper outlines important ties between three scholarly communities to illustrate how their combined research expertise is crucial to advancing how we understand learning and for developing LA-based interventions that meet the values that we all share.
Being a management accountant in a shared services centre
Authors: Lepistö Lauri , Dobroszek Justyna , Moilanen Sinikka , Zarzycka Ewelina 
Published: November 2018

Purpose
The purpose of this paper is to improve understanding of the work of management accountants in the context of a shared services centre.

Design/methodology/approach
A single case study method is used and data are collected via semi-structured interviews and internal documents. The empirical materials are analysed from the theoretical perspective of dirty work, incorporating aspects from practice theory.

Findings
Findings suggest that management accountants working in a shared services centre develop their occupational esteem by refocusing and reframing strategies. Through these strategies, management accountants can decrease the perceived “dirtiness” associated with their work.

Originality/value
The study sheds light on the under-researched topic of management accountants’ work within a shared services centre. Moreover, it offers the metaphor of liminal work to characterise how management accountants develop their occupational esteem in circumstances where gaining efficiency is the main objective.
On the ground insights from disability professionals supporting people with intellectual disability who have experienced sexual violence
Authors: Fraser-Barbour Ellen Frances 
Published: November 2018

Purpose
The purpose of this paper is report on a study exploring the views of service providers, both within disability service sectors and in mainstream violence response sectors, about ways of effectively supporting people with intellectual disability who may be experiencing abuse and violence.

Design/methodology/approach
Semi-structured interviews were conducted with seven participants and analysed both thematically and in more depth from a socio-ecological perspective.

Findings
Participants highlighted five key factors facilitating or hindering professionals working with individuals with intellectual disability who may be experiencing abuse and violence: connecting clients with services and establishing a rapport; access to information about histories of trauma; policy context; inaccessibility and unavailability of mainstream violence response services; client understanding of what happens “next” after identification of harm.

Originality/value
Overall the study indicates a strong need for the development of resources, information and tools designed to educate and enhance the understanding of professionals supporting people with ID and to better facilitate learning and understanding for people with ID regarding what happens “after” disclosure of sexual violence or other experiences of harm.
Parents’ and children’s violent gameplay: role of co-playing
Authors: Walker Doug , Brocato E. Deanne , Carlson Les , Laczniak Russell N. 
Published: November 2018

Purpose
The purpose of this study is to explore the role of co-playing as a moderator of the relation between parents’ and children’s play of violent video games.

Design/methodology/approach
The study uses dyadic parent/child survey data to estimate the conditional effects in the model, both direct and indirect.

Findings
The positive effect of parents’ violent video game play of children’s playing behaviors is attenuated by parent/child co-playing. Parents’ knowledge of the Entertainment Software Rating Board (ESRB) ratings leads to higher levels of co-playing, thereby indirectly attenuating violent video game play in children as driven by parents’ play.

Research limitations/implications
The paper extends the literature on consumer socialization and the impact of co-playing and identifies an antecedent for co-playing in this context.

Practical implications
The paper reveals that knowledge of the self-regulatory ESRB rules plays a valuable (indirect) role in mitigating violent video game play by children through an increase in co-playing, which attenuates the positive effect of parents’ play on children’s play.

Originality/value
The study incorporates data from both parents and children to investigate the relationship between parents and children’s violent video game play while empirically investigating the uncertainty in the literature concerning the moderating impact of co-playing.
Developing health information literacy in disengaged at-risk populations
Authors: Buchanan Steven , Nicol Emma 
Published: November 2018

PurposeThe purpose of this paper is to advance our understanding of the challenges of health information literacy (IL) education in disadvantaged and disengaged at-risk populations; and from the perspective of professionals out with information professions occupying everyday support roles.Design/methodology/approachA qualitative in-depth case study. The participants were a team of UK Family Nurses providing outreach support to young expectant mothers from areas of multiple deprivations, and the mothers themselves. The data collection methods were observation, survey, interviews and focus groups.FindingsInformation needs of mothers are multiple, and not always recognised as information problems, or revealed. Several felt overwhelmed, and actively avoided health information. There is low awareness and/or use of state sources of online health information. Family nurses provide an important information intermediary role, but are unfamiliar with IL concepts and models; consequently, there is limited evidence of client transitions to independent information seeking, or underpinning pedagogical practices to achieve such goals.Research limitations/implicationsFurther research is required into appropriate pedagogical approaches to IL education adaptable to semi-structured everyday situations. Recognition of information need requires particular attention, including methods of elicitation and specification in the problematic context.Practical implicationsIn an era of digital transitions and public service reforms, the authors raise important questions regarding the true reach of public health policy.Originality/valueThe paper holistically examines nurse–client information behaviours, and extends the discussion of low IL in nurses beyond issues of evidence-based practice to issues of developing healthcare self-efficacy in at-risk clients.