bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do cognitive heuristics underpin symptom appraisal for symptoms of cancer?: A secondary qualitative analysis across seven cancers
Authors: Kummer Sonja , Walter Fiona M. , Chilcot Joseph , Emery Jon , Sutton Stephen , Scott Suzanne E. 
Published: March 2019

AbstractObjectivesTo explore the evidence for cognitive heuristics or “rules of thumb” used within patients' reports of symptom appraisal and decisions to seek help for symptoms of cancer.MethodsA secondary analysis of interviews from existing studies that explored symptom appraisal in patients who had sought help for potential symptoms of cancer. Transcripts from n = 50 in‐depth interviews with patients referred with symptoms suspicious of cancer (pancreas, colorectal, oral, lung, melanoma, breast, and prostate) were re‐analysed using a deductive thematic approach underpinned by the heuristics outlined in the Common Sense Model of Illness Self‐regulation as set within the Model of Pathways to Treatment.ResultsThe most dominant heuristic in patient reports was the Rate of change rule (ie, symptoms that are worsening, increasing, or have a sudden onset [rather than improving, stable or decreasing in number] are more likely to indicate illness). There was also support for the Duration rule, Pattern rule, Chronology rule, Severity (of interference) rule, Age‐illness rule, Novelty rule, Similarity rule, Location rule, and Optimistic bias rule. There was a lack of evidence for the Prevalence and Stress‐illness rules.ConclusionsPeople do appear to use heuristics to guide their appraisal of symptoms and their perceived need for healthcare. Heuristics may be an important aspect underlying symptom misinterpretation, thus making them key targets for interventions. For instance, campaigns could tackle cognitive biases rather than focusing on specific symptom awareness. Myth‐busting messages could highlight that intermittent, mild symptoms, and symptoms that are not worsening can be signs of a serious health problem.
Health literacy and cancer care coordination in Chinese migrant patients and their carers: A cross‐sectional survey
Authors: Lim Bee Teng , Huang Yi‐Jing , Shepherd Heather L. , Shaw Joanne , Costa Daniel , Durcinoska Ivana , Young Jane M. , White Kate , Sze Minglo , Butow Phyllis 
Published: March 2019

AbstractObjectivesThis study aimed to describe the levels of health literacy and experience of care coordination among Chinese migrant patients with cancer and their carers in Australia, and to examine factors associated with these.MethodsPatients' self‐reported data were collected using the Health Literacy and Cancer Care Coordination questionnaires. We conducted multivariate linear regression analyses to investigate predictors of patients' health literacy and their care experience. Canonical correlation analysis was used to examine the relationship between patients' health literacy and their care experience.ResultsA total of 68 patients and eight carers participated in the survey. Patients and carers reported similar levels of health literacy, with the lowest scores being in the “Having sufficient information to manage health” and “Navigating the health system” subscales. Gender (P = 0.026, partial η2 = 0.281) and educational attainment (P = 0.015, partial η2 = 0.250) had significant and large effects on patients' health literacy, after controlling for each other. Educational attainment showed a significant and medium association with patients' experience of cancer care coordination (P = 0.041, partial η2 = 0.101). A large and positive correlation was found between patients' health literacy and experience of cancer care coordination (canonical correlation = 0.81).ConclusionsOur findings reveal the health literacy and care coordination needs of Chinese migrant patients with cancer in Australia, especially those with lower educational attainment. Future efforts are necessary to enhance Chinese migrants' health literacy and establish an accessible and easy‐to‐navigate care environment.
Ratiometric Fluorescent Detection of ClO− Based on Dual‐Emission F1‐Rubpy@Nanoscale Metal‐Organic Frameworks
Authors: Cai Keying , Zeng Mulan , Wang Li , Song Yonghai , Chen Lili 
Published: March 2019

AbstractHerein, a facile one‐pot strategy was developed to synthesize novel dual‐emission nanoscale ZnMOF74 encapsulating with fluorescein o‐acrylate (F1) and tris(2,2’‐bipyridyl)‐dichroruthenium(II) hexahydrate (Rubpy) (F1‐Rubpy@ZnMOF74). The as‐prepared dual‐emission F1‐Rubpy@ ZnMOF74 nanocomposites were characterized by scanning electron microscopy, X‐ray powder diffraction, N2 adsorption/desorption isotherms and fluorescence techniques. The results showed F1‐Rubpy@ZnMOF74 nanocomposites were spherical with diameter of 100–300 nm, and exhibited good water dispersion. F1 and Rubpy were uniformly encapsulated in the pores of ZnMOF74. The nanosensor displayed strong emission peaks of F1 at 512 nm and Rubpy at 600 nm. The I512nm/I600nm decreased with increasing concentration of ClO− in the range of 3.6 nM‐100 μM with low detection limit of 1.2 nM. The nanocomposites also showed high sensitivity, selectivity and stability, which was expected to apply in quality testing of industrial goods and further biological cell experiments. The work also provides a good method to construct ratiometric fluorescent sensors based on MOFs.
Design, Synthesis and Pharmacological Evaluation of Noscapine Glycoconjugates
Authors: Mishra Kunj B , Tiwari Neeraj , Bose Priyanka , Singh Rajan , Rawat Arun K , Singh Sumit K. , Mishra Ram C. , Singh Rakesh K , Tiwari Vinod K. 
Published: March 2019

AbstractThe present work is directed to design a series of molecules which are hybrids of two non‐toxic biocompatible chemical architectures, noscapine and carbohydrates. Fourteen, 7‐O‐noscapine analogues have been synthesized out of which one of the analogue is 7‐O‐propargylated derivative and others are in its glycoconjugate form with triazole bridging achieved via Click reaction, where dinuclear copper(I) thiodiacetate complex [(PPh3)2Cu(μ‐tda)Cu(PPh3)2].6H2O has been emerged as an excellent catalyst for the noscapine‐glyco Click‐coupling. All the developed noscapine glycoconjugates have been investigated for anticancer activity using HeLa cell line and anti‐leishmanial activity against Leishmania donovani. Result indicates that five of the developed noscapine glycoconjugates (5 a, 5 b, 5 c, 5 e and 5 l) showed significant anti‐proliferative activity. On the other hand, four of them (5 b, 5 c, 5 e, and 5 l) showed significant anti‐leishmanial activity.
Simple and Green Procedures for the Synthesis of 3,5‐Bis(alkylthio)‐1,2,4‐thiadiazoles via Oxidative Dimerization of Dithiocarbamates
Authors: Halimehjani Azim Ziyaei , Sharifi Ali , Rahimzadeh Hossein 
Published: March 2019

AbstractOxidative dimerization of S‐alkyl dithiocarbamates with molecular iodine and oxone were applied as efficient protocols for the synthesis of 3,5‐bis(alkylthio)‐1,2,4‐thiadiazoles. Performing the reactions in green solvents, obtaining excellent yield of products under mild reaction conditions, avoiding the use of transition metals and hypervalent iodines, and using inexpensive, readily available, safe and environmentally benign oxidants are the main advantages of these protocols. In addition, the reported methods in this paper allow chemists to synthesize the title compounds both in organic and aqueous media.
Solvent‐Induced Self‐Assembly of Naphthalenediimide Conjugated to Tetraphenylethene through D‐ and L‐Alanine
Authors: Goskulwad Santosh P. , More Vishal G. , Kobaisi Mohammad Al , Bhosale Rajesh S. , La Dung Duc , Antolasic Frank , Bhosale Sidhanath V. , Bhosale Sheshanath V. 
Published: March 2019

AbstractHerein, the synthesis and supramolecular self‐assembly of naphthalenediimide (NDI)‐tetraphenylethene (TPE) conjugates with l‐alanine (coded as: 1) and d‐alanine (coded as: 2) was investigated. The pair stereoisomer molecules were designed to undergo self‐assembly under solvophobic effects. Mixtures of THF–water was used to fine tune the solvophobic effect leading to microbelt for both 1 and 2 in 40% v/v of THF in H2O, while microbelt and particulate microsphere supramolecular structures were observed in 20%, v/v THF in H2O. When 10% THF in H2O was employed derivative 1 produces belt‐like structures, however, 2 produces microsphere. Less uniformly defined microstructure morphologies of 1 and 2 were formed in THF/hexane and DCM/hexane. The solvophobic effect on self‐assembly further evidenced using UV/Vis, fluorescence, circular dichroism, X‐ray diffraction (XRD) spectroscopies. DLS used to evaluate formation of assembly in solution, DFT (density functional theory) and TD‐DFT (time dependent density functional theory) molecular modelling support the hypothesis. Scanning electron microscopy used to visualise formation of supramolecular self‐assembled nano‐ and micro‐structures.
Redox Additive Electrolyte Study of Mn–MOF Electrode for Supercapacitor Applications
Authors: Sundriyal Shashank , Shrivastav Vishal , Sharma Meenu , Mishra Sunita , Deep Akash 
Published: March 2019

AbstractThe selection of appropriate electrode materials and electrolytes in addition to optimization of their combinations is a key to improve the performance of supercapacitors. Among the new electrode materials, metal‐organic frameworks (MOFs) based electrodes are attracting attention in energy storage devices, including supercapacitors and batteries. In recent years, the redox additive electrolytes have been projected as efficient options over simple aqueous electrolytes. The present work reports the synthesis of a layered MOF, i. e., manganese‐1,4‐ benzene dicarboxylate (Mn‐BDC) and explores its utility as a supercapacitor electrode in the presence of an optimized redox additive electrolyte (0.2 M K3[Fe(CN)6] in 1 M Na2SO4 (0.2 M KFCN)). As demonstrated for the first time in this study, the combined use of the porous Mn‐BDC electrode and KFCN electrolyte has provided a synergistic enhancement in the supercapacitor performance. The present Mn‐BDC/KFCN combination has delivered a high specific capacitance of 1590 F/g at a current density of 3 A/g. Furthermore, the Mn‐BDC electrode could retain around 82% of its initial specific capacitance even after 3000 continuous charge‐discharge cycles. In view of its encouraging electrochemical performance parameters, the proposed system can be touted as an efficient supercapacitor assembly.
Depolymerization of End‐of‐Life Poly(bisphenol A carbonate) via Transesterification with Acetic Anhydride as Depolymerization Reagent
Authors: Alberti Christoph , Scheliga Felix , Enthaler Stephan 
Published: March 2019

AbstractThe chemical recycling, a combination of depolymerization and polymerization processes, of end‐of‐life plastics/polymers can contribute to a more sustainable, resource‐conserving and environmental‐benign society. In this regard, we have set up a capable procedure for the chemical recycling of the bisphenol A unit of poly(bisphenol A carbonate). In more detail, acetic acid or acetic anhydride were used as depolymerization reagent in the DMAP‐catalyzed conversion of end‐of‐life poly(bisphenol A carbonate) to obtain bisphenol A diacetate as well‐defined product. Moreover, it was demonstrated that bisphenol A diacetate in combination with diphenyl carbonate can be applied in the potassium tert‐butoxide catalyzed synthesis of new poly(bisphenol A carbonate). In consequence a recycling of poly(bisphenol A carbonate) is feasible.
Das Schalentragwerk des Kuwait International Airport Terminal 2 – Bemessung und Ausführung einer komplexen Megastruktur in Zeiten der Digitalisierung
Authors: Blandini Lucio , Nieri Guido , Sobek Werner 
Published: March 2019

AbstractDer internationale Flughafen von Kuwait wird bis 2022 um ein neues Terminalgebäude nach einem Entwurf von Foster + Partner erweitert. Das neue Terminal hat eine Kantenlänge von fast 1,2 km, eine lichte Höhe von bis zu 25 m und eine Dachfläche von 320 000 m 2. Das Gebäude zeichnet sich aber nicht nur durch seine Größe, sondern auch durch die Komplexität seines Dachtragwerks aus. Trotz seines großen Umfangs musste das Dach ohne Dehnfugen geplant werden. Dies hatte umfangreiche Auswirkungen auf Bemessung und Berechnung aller Bauteile. Das Dachtragwerk ist ein statisch hochgradig unbestimmtes System. Die Interaktion zwischen den verschiedenen Komponenten ist hierdurch sehr komplex, sodass jede Steifigkeitsänderung bei einem Element maßgeblichen Einfluss auf die statische Auslastung der anderen Bauteile hat. Der vorliegende Aufsatz beschreibt, wie dieser anspruchsvolle Entwurf mithilfe komplexer digitaler Methoden und Werkzeuge realisierbar gemacht werden konnte.
Intelligent wind turbine gearbox diagnosis using VMDEA and ELM
Authors: Isham Muhammad Firdaus , Leong Muhammad Salman , Lim Meng Hee , Bin Ahmad Zair Asrar 
Published: March 2019

AbstractWind turbine gearbox diagnosis is a vital tool for maintaining wind turbine operation and safety. The gearbox vibration signal is invariably complex and variable, and useful information and features are difficulty of extraction. Recently, a new and adaptive signal decomposition method, known as variational mode decomposition (VMD), has been proposed, which helps to improve the efficiency and effectiveness of extracting features from gearbox vibration signals. However, the performance of the VMD method mainly depends on its input parameters, especially the mode number and balancing parameter (also called the quadratic penalty term). Hence, this paper proposes a selection method for an optimized VMD parameter using differential evolution algorithm (DEA), also called VMDEA. Firstly, the VMDEA is used to select optimized VMD input parameters for each of the vibration signals. Following this, VMD decomposes each vibration signal into sets of subsignals using the selected optimized parameter. Multidomain features are extracted from VMD reconstructed signals and are passed on to the extreme learning machine (ELM) for fault classification. This study can thus provide a good solution for determining an optimized VMD parameter for decomposing vibration signals and can also provide a more efficient and effective diagnostic approach to wind turbine gearbox maintenance.
Open forest management for early successional birds
Authors: Hanberry Brice B. , Thompson Frank R. 
Published: March 2019

ABSTRACTWildlife biologists classify some bird species as early successional because of apparent dependence on early successional vegetation such as forbs, grasses, shrubs, and small trees. We propose that many “early successional” species were more often associated with open forests such as savannas and woodlands, which covered a much greater extent of the eastern United States under historical disturbance regimes than more ephemeral early successional forest. We draw on several lines of evidence, including knowledge of historical ecosystems and disturbance, landscape analyses, and general literature review to evaluate benefits of open forest ecosystems for early successional birds. Early successional forests covered 1–13% of forestlands in the eastern United States prior to Euro‐American settlement, whereas open forests covered large extents of the United States. Many early successional songbirds reach great densities in open forests and potentially greater numbers in landscapes with historical amounts of open forest than in present‐day landscapes and those under intensive even‐aged forest management. Restoration and management of open forests has not been prioritized or well‐articulated for management of early successional birds and other species. Although both early successional forests and open forests provide habitat for birds, we suggest the great reduction in the historical extent of open forests needs to be addressed through greater restoration and management of open forests if we want to better meet the needs of some early successional birds and other wildlife. Published 2019. This article is a U.S. Government work and is in the public domain in the USA.
Entanglement-assisted quantum error-correcting codes over arbitrary finite fields
Authors: Galindo Carlos , Hernando Fernando , Matsumoto Ryutaroh , Ruano Diego 
Published: March 2019

AbstractWe prove that the known formulae for computing the optimal number of maximally entangled pairs required for entanglement-assisted quantum error-correcting codes (EAQECCs) over the binary field hold for codes over arbitrary finite fields as well. We also give a Gilbert–Varshamov bound for EAQECCs and constructions of EAQECCs coming from punctured self-orthogonal linear codes which are valid for any finite field.
Tighter Blood Pressure Control Is Associated with Lower Incidence of Erectile Dysfunction in Hypertensive Men
Authors: Hsiao Wayland , Bertsch Ruth Ann , Hung Yun-Yi , Aaronson David S. 
Published: March 2019

Abstract

Introduction
Tighter blood pressure control is widely thought to be associated with better erectile function, although the preponderance of data is limited to dichotomous representations of hypertension without an attempt to look at degree of blood pressure control.

Aim
To determine the association between optimal blood pressure control over time and the development of erectile dysfunction (ED) in a cohort of potent men.

Methods
We performed a retrospective cohort study of newly diagnosed hypertensive men without major medical comorbidities in an integrated healthcare system. Patients were stratified by exposure to hypertension, with varying levels of blood pressure control, as measured by ordinal categories of systolic blood pressure and deviation from the mean systolic pressure.

Main Outcome Measures
Incidence of ED was defined by at least 2 primary care or urology diagnoses of ED in our electronic health records within 2 years, at least 2 filled prescriptions for ED medications within 2 years, or 1 diagnosis of ED and 2 filled prescriptions for ED medications.

Results
We identified 39,320 newly diagnosed hypertensive men. The overall incidence for ED was 13.9%, with a mean follow-up of 55.1 ± 28.7 months. Higher average systolic blood pressure was associated with a higher risk of ED in a dose-dependent manner (trend test, P &lt; .001). Wide variation in blood pressure control was associated with a higher incidence of ED (OR [95% CI]; 1.359 [1.258–1.469]) and a shorter time to the development of ED (log rank, P &lt; .0001).

Clinical Implications
We believe these data may serve as a motivator for hypertensive men to better adhere to their hypertension treatment regimen.

Strength & Limitations
The retrospective nature of our study precludes us from drawing more than an association between tighter blood pressure control and ED. Strengths of our study include the large sample size, community cohort, and completeness of follow-up.

Conclusion
Among adults diagnosed with hypertension, tighter blood pressure control, as measured by average systolic blood pressure and deviation from the average, is associated with a lower incidence and a longer time to the development of ED.
Advances in Documentation of Commingled and Fragmentary Remains
Authors: Osterholtz Anna J. 
Published: March 2019

AbstractCommingled and fragmentary remains are found in numerous contexts worldwide. These assemblages typically require large scale, long term study to fully extract and contextualize meaningful data. However, when uncovered in CRM and foreign settings where remains cannot leave their country of origin, there is a need for quick, reliable data collection. Presented here is a recording system for use in field- and research-based laboratory settings. Utilizing visual forms and a minimal set of observations for skeletal elements from the cranium to the foot, the database facilitates data collection of fragment identification, age at death and sex estimation, dental observations, trauma recording, and taphonomic observations. A data dictionary is also provided, with definitions and value lists used in the database itself. The database has been used in field labs throughout the old world and by numerous researchers who have modified it to meet their own research needs. By presenting a minimal standard of data in a highly adaptable database, the recording system described here provides consistent baseline data in a user-friendly, quick-access format
Field Conservation of Skeletal Remains: Stabilization Treatment Techniques and Implications for Future Analysis
Authors: Beaubien Harriet F. 
Published: March 2019

AbstractThe information potential of human skeletal remains—as for any excavated material—is impacted by the conditions of archaeological burial, and the environments and actions experienced during subsequent excavation, laboratory processing, study, and storage. A conservation approach emphasizes the mitigation of threats to material stability and integrity, which for excavated collections are often most critical at the point of archaeological exposure and recovery. Conservation techniques involving application of modern synthetic materials for stabilizing skeletal remains in the field are discussed, using case examples primarily from terrestrial archaeological projects in Mesoamerica. The potential effects of the use of various conservation materials on results of biomolecular instrumental analysis are included.
Linkages between geochemistry and microbiology in a proglacial terrain in the High Arctic
Authors: Wojcik Robin , Donhauser Jonathan , Frey Beat , Holm Stine , Holland Alexandra , Anesio Alexandre M. , Pearce David A. , Malard Lucie , Wagner Dirk , Benning Liane G. 
Published: March 2019

ABSTRACTProglacial environments are ideal for studying the development of soils through the changes of rocks exposed by glacier retreat to weathering and microbial processes. Carbon (C) and nitrogen (N) contents as well as soil pH and soil elemental compositions are thought to be dominant factors structuring the bacterial, archaeal and fungal communities in the early stages of soil ecosystem formation. However, the functional linkages between C and N contents, soil composition and microbial community structures remain poorly understood. Here, we describe a multivariate analysis of geochemical properties and associated microbial community structures between a moraine and a glaciofluvial outwash in the proglacial area of a High Arctic glacier (Longyearbreen, Svalbard). Our results reveal distinct differences in developmental stages and heterogeneity between the moraine and the glaciofluvial outwash. We observed significant relationships between C and N contents,δ13Corgandδ15N isotopic ratios, weathering and microbial abundance and community structures. We suggest that the observed differences in microbial and geochemical parameters between the moraine and the glaciofluvial outwash are primarily a result of geomorphological variations of the proglacial terrain.