bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENERIMAAN ORANGTUA TERHADAP ANAK DENGAN AUTISME DI PUSAT LAYANAN AUTIS (PLA) DAERAH ISTIMEWA YOGYAKARTA
Authors: Rahadian Syah Deby Zulkarnain , Sutarjo Puji , Riescananda Inna 
Published: March 2018

ABSTRACT
Background: Autism is a developmental disorder in children that affects their social and imaginative lifes. Parents’ acceptance on their children’s autism will have impact on how they treat their children.
Objective: The aim of this study was to determine the parental acceptance of children with autism in the Autism Services Center (ASC), Yogyakarta.
Methods: This study was a qualitative research with a phenomenological approach. The data collection was conducted by in-depth interviews with three informans.
Results: All the informants accepted their children’s conditions, after getting information about autism. Acceptance of parents indicated their satisfaction with the children’s talent. Parents provide facilities to support the children's talents. In addition, the acceptance of parents indicated by the acceptance of the cildren’s limitations.
Conclusion: Participants accepted their children’s conditions, talents and limitations.
Keywords: Autism, Parental Acceptance.
Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database
Authors: Lehrer Steven , Rheinstein Peter H. 
Published: March 2018

Background: Studies of Alzheimer’s disease suggest that neuroinflammation or deranged brain wound healing may be a cause of some cases. But a placebo controlled study showed no effect at all on Alzheimer’s disease of low dose oral prednisone after one year. Introducing the steroid directly into the hippocampus and rhinencephalon via the nose, as happens in hay fever subjects, could be more effective. Objective: In the present study, we analyzed FDA MedWatch data for intranasal fluticasone propionate (Flonase) to determine the frequency of Alzheimer’s disease as an adverse event reported after use of the medication. Methods: Machine-readable data from MedWatch, including adverse drug reaction reports from manufacturers, are part of a public database. We used the online tool eHealthMe to query the database. Results: By September 20, 2017, 35,221 people reported side effects to MedWatch after taking Flonase. Among them, 9 people (0.03%) had Dementia Alzheimer’s type. By October 3, 2017, 185,636 people reported side effects after taking Lipitor. Among them, 243 people (0.13%) had Dementia Alzheimer’s type. The lower incidence of Alzheimer’s dementia in the Flonase group compared to the Lipitor group was significant ( p <  0.001, Fisher exact test, two tailed). Conclusion: Long term use of oral non-steroidal anti-inflammatory drugs (NSAIDs) is linked with reduced risk of developing Alzheimer’s disease. Data from MedWatch suggest that fluticasone propionate administered intranasally might have a similar preventive effect to ibuprofen. Perhaps combining ibuprofen and Flonase could be therapeutic. Further studies would be desirable.
Effect of sequence order of combined strength and endurance training on new adiposity indices in overweight elderly women
Authors: Faramarzi Mohammad , Bagheri Laleh , Banitalebi Ebrahim 
Published: March 2018

BACKGROUND: Obesity and physical inactivity increase the risk for cardiovascular disease, Type 2 diabetes mellitus, hypertension, dyslipidemia and certain cancers. Exercise training and increased fitness promote positive changes in body composition and improve insulin sensitivity. OBJECTIVE: To investigate the effect of sequence order of combined strength and endurance training on new adiposity indices: visceral adiposity index (VAI), body adiposity index (BAI) and waist to hip ratio (WHtR) in overweight elderly women. METHODS: Forty overweight elderly women (age range: 60.34 [Formula: see text] 0.82 years old) were selected purposefully and randomly assigned into four groups: endurance, then strength (E[Formula: see text] [Formula: see text]S) ([Formula: see text]), strength, then endurance (S[Formula: see text]E) ([Formula: see text]), alternative concurrent training (ACT) ([Formula: see text]), and control ([Formula: see text]) groups. Training was performed three times per week for eight weeks. Endurance training performed on a cycle ergometer (intensity: 60–88% MHR) and strength training included several selected exercises targeting upper and lower body (intensity: 40–75 1RM, 8–18 repeat). RESULTS: The results showed that the amount of weight, BMI, body fat percentage, BAI and WHtR have significantly decreased in E [Formula: see text] S, S [Formula: see text] E and ACT experimental groups ([Formula: see text] 0.05). No significant differences were found in VAI variable and triglyceride with sequence order of E [Formula: see text] S and S [Formula: see text] E, but after sequence order of ACT a significant decrease was seen in both variables ([Formula: see text] 0.05). There were no statistically significant differences between the three combined training groups for the mentioned variables ([Formula: see text] 0.05). CONCLUSION: Sequence does not seem to play a role in the positive effect on current adiposity indices of the investigated training programs.
Orbit and Dynamical Mass of the Late-T Dwarf GL 758 B*
Authors: Bowler Brendan P. , Dupuy Trent J. , Endl Michael , Cochran William D. , MacQueen Phillip J. , Fulton Benjamin J. , Petigura Erik A. , Howard Andrew W. , Hirsch Lea , Kratter Kaitlin M. , Crepp Justin R. , Biller Beth A. , Johnson Marshall C. , Wittenmyer Robert A. 
Published: March 2018

Abstract
Gl 758 B is a late-T dwarf orbiting a metal-rich Sun-like star at a projected separation of ρ ≈ 1.″6 (25 au). We present four epochs of astrometry of this system with NIRC2 at Keck Observatory spanning 2010 to 2017 together with 630 radial velocities (RVs) of the host star acquired over the past two decades from McDonald Observatory, Keck Observatory, and the Automated Planet Finder at Lick Observatory. The RVs reveal that Gl 758 is accelerating with an evolving rate that varies between 2 and 5 m s−1 yr−1, consistent with the expected influence of the imaged companion Gl 758 B. A joint fit of the RVs and astrometry yields a dynamical mass of

M
Jup for the companion with a robust lower limit of 30.5 M
Jup at the 4-σ level. Gl 758 B is on an eccentric orbit (e = 0.26–0.67 at 95% confidence) with a semimajor axis of a =

au and an orbital period of P =

yr, which takes it within ≈9 au from its host star at periastron passage. Substellar evolutionary models generally underpredict the mass of Gl 758 B for nominal ages of 1–6 Gyr that have previously been adopted for the host star. This discrepancy can be reconciled if the system is older—which is consistent with activity indicators and recent isochrone fitting of the host star—or alternatively if the models are systematically overluminous by ≈0.1–0.2 dex. Gl 758 B is currently the lowest-mass directly imaged companion inducing a measured acceleration on its host star. In the future, bridging RVs and high-contrast imaging with the next generation of extremely large telescopes and space-based facilities will open the door to the first dynamical mass measurements of imaged exoplanets.
Infrared Spectroscopy of Carbonaceous-chondrite Inclusions in the Kapoeta Meteorite: Discovery of Nanodiamonds with New Spectral Features and Astrophysical Implications
Authors: Abdu Yassir A. , Hawthorne Frank C. , Varela Maria E. 
Published: March 2018

Abstract
We report the finding of nanodiamonds, coexisting with amorphous carbon, in carbonaceous-chondrite (CC) material from the Kapoeta achondritic meteorite by Fourier-transform infrared (FTIR) spectroscopy and micro-Raman spectroscopy. In the C–H stretching region (3100–2600 cm−1), the FTIR spectrum of the Kapoeta CC material (KBr pellet) shows bands attributable to aliphatic CH2 and CH3 groups, and is very similar to IR spectra of organic matter in carbonaceous chondrites and the diffuse interstellar medium. Nanodiamonds, as evidenced by micro-Raman spectroscopy, were found in a dark region (∼400 μm in size) in the KBr pellet. Micro-FTIR spectra collected from this region are dramatically different from the KBr-pellet spectrum, and their C–H stretching region is dominated by a strong and broad absorption band centered at ∼2886 cm−1 (3.47 μm), very similar to that observed in IR absorption spectra of hydrocarbon dust in dense interstellar clouds. Micro-FTIR spectroscopy also indicates the presence of an aldehyde and a nitrile, and both of the molecules are ubiquitous in dense interstellar clouds. In addition, IR peaks in the 1500–800 cm−1 region are also observed, which may be attributed to different levels of nitrogen aggregation in diamonds. This is the first evidence for the presence of the 3.47 μm interstellar IR band in meteorites. Our results further support the assignment of this band to tertiary CH groups on the surfaces of nanodiamonds. The presence of the above interstellar bands and the absence of shock features in the Kapoeta nanodiamonds, as indicated by Raman spectroscopy, suggest formation by a nebular-condensation process similar to chemical-vapor deposition.
Interstellar Object ’Oumuamua as an Extinct Fragment of an Ejected Cometary Planetesimal
Authors: Raymond Sean N. , Armitage Philip J. , Veras Dimitri 
Published: March 2018

Abstract
’Oumuamua was discovered passing through our solar system on a hyperbolic orbit. It presents an apparent contradiction, with colors similar to those of volatile-rich solar system bodies but with no visible outgassing or activity during its close approach to the Sun. Here, we show that this contradiction can be explained by the dynamics of planetesimal ejection by giant planets. We propose that ’Oumuamua is an extinct fragment of a comet-like planetesimal born a planet-forming disk that also formed Neptune- to Jupiter-mass giant planets. On its pathway to ejection ’Oumuamua’s parent body underwent a close encounter with a giant planet and was tidally disrupted into small pieces, similar to comet Shoemaker–Levy 9’s disruption after passing close to Jupiter. We use dynamical simulations to show that 0.1%–1% of cometary planetesimals undergo disruptive encounters prior to ejection. Rocky asteroidal planetesimals are unlikely to disrupt due to their higher densities. After disruption, the bulk of fragments undergo enough close passages to their host stars to lose their surface volatiles and become extinct. Planetesimal fragments such as ’Oumuamua contain little of the mass in the population of interstellar objects but dominate by number. Our model makes predictions that will be tested in the coming decade by the Large Synoptic Survey Telescope.
A High-precision Trigonometric Parallax to an Ancient Metal-poor Globular Cluster∗
Authors: Brown T. M. , Casertano S. , Strader J. , Riess A. , VandenBerg D. A. , Soderblom D. R. , Kalirai J. , Salinas R. 
Published: March 2018

Abstract
Using the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST), we have obtained a direct trigonometric parallax for the nearest metal-poor globular cluster, NGC 6397. Although trigonometric parallaxes have been previously measured for many nearby open clusters, this is the first parallax for an ancient metal-poor population—one that is used as a fundamental template in many stellar population studies. This high-precision measurement was enabled by the HST/WFC3 spatial-scanning mode, providing hundreds of astrometric measurements for dozens of stars in the cluster and also for Galactic field stars along the same sightline. We find a parallax of 0.418 ± 0.013 ± 0.018 mas (statistical, systematic), corresponding to a true distance modulus of 11.89 ± 0.07 ± 0.09 mag (2.39 ± 0.07 ± 0.10 kpc). The V luminosity at the stellar main-sequence turnoff implies an absolute cluster age of 13.4 ± 0.7 ± 1.2 Gyr.
Impact des patients « bed blockers » sur les coûts hospitaliers et évaluation des obstacles à la sortie, étude prospective au sein de quatre hôpitaux belges
Authors: De Foor Julie , Leclercq Pol , Van Den Bulcke Julie , Pirson Magali 
Published: March 2018

Introduction : Les hôpitaux constatent régulièrement que la durée de séjour à l’hôpital de certains patients est prolongée bien que leur présence ne soit plus justifiée par des raisons médicales. Le manque d’infrastructures extrahospitalières pouvant accueillir des patients après une hospitalisation peut avoir un impact sur les coûts des hôpitaux. L’objectif de l’étude est d’établir les profils des patients bed blockers , d’identifier les obstacles à leur sortie, le besoin en structures d’accueil adéquates après l’hospitalisation, de calculer la durée excédentaire du séjour, et d’en évaluer le coût pour les hôpitaux. Méthodes : Une enquête a été réalisée dans quatre hôpitaux belges. Les patients qui sont toujours hospitalisés, alors que l’autorisation médicale de sortie remonte à plus de 24 heures, ont été recensés sur une période de 21 ou 30 jours. L’étude se concentre sur 93 patients. Résultats : Nous distinguons quatre profils de patients bed blockers . 33% des patients sont en attente d’un lit en maison de repos et de soins (MRS) ou une maison de repos pour personnes âgées (MRPA) (groupe A). Ils ont une durée de séjour excédentaire moyenne (écart type) de 13 jours (12), ce qui représente un coût moyen par patient de 8.197 EUR pour l’hôpital. Les patients du groupe B ont besoin d’un accueil temporaire pour leur permettre de restaurer leur autonomie avant de retourner dans leur environnement familial naturel (21%). Ils ont une durée excédentaire moyenne de 3 jours (2), ce qui représente un coût moyen de 2.392 EUR. Les patients du groupe C nécessitent de la revalidation après l’hospitalisation (34%). Ils ont une durée de séjour excédentaire moyenne de 11 jours (18), ce qui représente un coût moyen par patient de 10.070 EUR. Le groupe D reprend les patients pour lesquels il n’existe pas ou peu de solutions de placement. Ils représentent 11% de la population étudiée et ont des profils variés et hétérogènes. L’obstacle principal à la sortie des patients de l’hôpital est un problème de disponibilité ou d’absence de l’offre de soins. Discussion/Conclusion : Les résultats montrent la nécessité de développer des lits de revalidation et de maisons de repos comme première solution permettant la sortie de patients dans des délais raisonnables.
Maillage territorial des établissements de santé : apport des modèles issus de la théorie des graphes
Authors: Le Meur Nolwenn , Ferrat Lauric , Gao Fei , Quidu Frédérique , Louazel Michel 
Published: March 2018

La recomposition hospitalière observable depuis plus de 20 ans en France résulte de décisions prises dans le cadre des politiques de planification et des stratégies adoptées par les établissements. Au-delà de ses conséquences, comment dans un premier temps rendre compte du maillage territorial des établissements de santé ? Pour identifier les facteurs caractérisant la topologie du maillage, les statistiques de test conventionnelles sont inadaptées. Aussi nous proposons dans cet article méthodologique, d’étudier l’utilité des modèles issus de la théorie des graphes pour la modélisation des transferts de patients entre établissements de courts séjours (i.e. Médecine-Chirurgie-Obstétrique, MCO) et établissements de soins de suites et réadaptation (SSR) à partir du Programme de Médicalisation des Systèmes d’Information (PMSI). Les modèles Erdös-Renyi (ER) et les modèles à séquences contraintes sur les degrés ( Constrainted Degree Sequence Model , CDSM) testent la significativité des mesures d’assortativité. Dans notre étude, ils démontrent entre autre la propension des établissements de même statut juridique à échanger des patients entre-eux. Les modèles en blocs permettent de créer des clusters d’établissements sur la base des caractéristiques communes. Dans notre contexte, ils soulignent notamment la dynamique territoriale des échanges entre établissements. Enfin, les modèles à graphes aléatoires exponentiels ( Exponential Random Graph Models ou ERGM) et la mesure d’assortativité mesurent l’influence simultanée de la proximité géographique et des statuts juridiques dans la relation entre les établissements. En conclusion, les méthodes issues de la théorie des graphes offrent des perspectives pour identifier et quantifier l’impact de facteurs pouvant influencer la topologie des relations hospitalières.
L’éthique du complexe scientifico-technique selon Dominique Dubarle
Authors: Faes Hubert 
Published: March 2018

D. Dubarle, dominicain, épistémologue, a réfléchi dans de nombreux articles sur l’impact des sciences et des techniques dans l’histoire et les sociétés humaines. Selon les grandes lignes de cette réflexion, le complexe scientifico-technique n’est en rien promesse d’un mal ou d’un bien assuré pour l’humanité, mais il entraîne des formes nouvelles d’action et de socialisation qui sont un défi éthique et politique. Il invitait à prospecter l’avenir qu’il nous prépare et de reconnaître les responsabilités qui nous incombent. Malgré certaines apparences, ses réflexions demeurent d’actualité.
A comparative study of auroral morphology distribution between the Northern and Southern Hemisphere based on automatic classification
Authors: Yang Qiuju , Hu Ze-Jun 
Published: March 2018

Abstract. Aurora is a very important geophysical phenomenon in the high
latitudes of Arctic and Antarctic regions, and it is important to make a
comparative study of the auroral morphology between the two hemispheres.
Based on the morphological characteristics of the four labeled dayside
discrete auroral types (auroral arc, drapery corona, radial corona
and hot-spot aurora) on the 8001 dayside auroral images at the Chinese Arctic Yellow
River Station in 2003, and by extracting the local binary pattern (LBP)
features and using a k-nearest classifier, this paper performs an automatic
classification of the 65 361 auroral images of the Chinese Arctic Yellow River
Station during 2004–2009 and the 39 335 auroral images of the South Pole
Station between 2003 and 2005. Finally, it obtains the occurrence distribution of
the dayside auroral morphology in the Northern and Southern Hemisphere. The
statistical results indicate that the four dayside discrete auroral types
present a similar occurrence distribution between the two stations. To the best
of our knowledge, we are the first to report statistical comparative
results of dayside auroral morphology distribution between the Northern and
Southern Hemisphere.
Fanconi Syndrome in Irish Wolfhound Siblings
Authors: Bommer Nick X. , Brownlie Serena E. , Morrison Linda R. , Chandler Marge L. , Simpson James W. 
Published: March 2018

ABSTRACTThree juvenile male Irish wolfhound littermates presented with marked polyuria and polydipsia. The four female siblings were apparently unaffected. Diagnostic testing revealed glucosuria with normoglycemia, generalized aminoaciduria, hypokalemia and metabolic acidosis consistent with Fanconi syndrome. Renal ultrasonographic and histologic findings are presented. Cases were managed with a supplementation regimen based on a treatment protocol for Fanconi syndrome in basenjis. These dogs did not have angular limb deformities as documented previously in juvenile canine siblings with Fanconi syndrome. Fanconi syndrome has not been previously described in Irish wolfhound siblings.
Azotemia and Proteinuria in Dogs Infected with Babesia gibsoni
Authors: Ullal Tarini , Birkenheuer Adam , Vaden Shelly 
Published: March 2018

ABSTRACT
Babesiosis is a hemoprotozoal tick-borne disease that is commonly associated with thrombocytopenia and anemia; however, renal involvement has been documented in dogs. The purpose of this retrospective study was to document azotemia and proteinuria in dogs infected with Babesia sp. and to describe the response to antiprotozoal therapy. The electronic database of the North Carolina State University Vector Borne Disease Laboratory was searched to identify dogs who were diagnosed with babesiosis and to determine if they had proteinuria and/or azotemia. Dogs were excluded if they had coinfections or comorbidities known to cause glomerular injury. Of 35 dogs identified during the initial search, 5 were included; however, only 4 of these dogs had both pre- and posttreatment data. All five dogs were American pit bull terriers or American pit bull terrier-mixed breed dogs, were infected with Babesia gibsoni, and had hypoalbuminemia and proteinuria. Three dogs had azotemia. Responses to antiprotozoal treatment included normalization of (three) or increase in (one) serum albumin, resolution (one) or improvement (one) of azotemia, and reduction in proteinuria (two). Laboratory findings consistent with glomerular disease can be found in Babesia gibsoni-infected dogs, and treatment can lead to improvement of the azotemia and proteinuria.
Marine benthic communities and anthropogenic activities in Sept-Îles (Canada): a peaceful coexistence?
Authors: Dreujou Elliot , Archambault Philippe , McKindsey Christopher W 
Published: March 2018

With the development of coastal human activities comes the growing need to develop methods to describe their cumulative impacts on marine benthic communities at local geographic scales. Local assessments facilitate dialogue between multiple users of the ecosystem (industries, individuals) and allow to better understand variation among benthic communities in a given region. In this project, we aim to develop indicators of cumulative impacts to assess the environmental health of benthic ecosystems within industrialized regions in the Gulf of St. Lawrence at a small spatial scale (0.01 km2).
We selected coastal regions around Sept-Îles, where numerous human activities are present at different intensities (such as international shipping, fisheries or domestic and industrial wastes). Subtidal ecosystems were sampled in 2016-2017 to characterize macro-endobenthic diversity and abiotic parameters of the sediment. We calculated impact scores for each human activity based on the distance from the source and the magnitude of its impact. We thus identified hotspots of cumulative impact and changes in the biotic and abiotic compartments along impact gradients. These results will be used for the development of indicators of cumulative stress and to understand resilience and stability of bay-scale benthic communities.
Tobacco rattle virus-inducedPHYTOENE DESATURASE(PDS)andMg-chelatase H subunit(ChlH) gene silencing inSolanum pseudocapsicumL.
Authors: Xu Hua , Xu Leifeng , Yang Panpan , Cao Yuwei , Tang Yuchao , He Guoren , Yuan Suxia , Ming Jun 
Published: March 2018

Virus-induced gene silencing (VIGS) is an attractive tool for determining gene function in plants. The present study constitutes the first application of VIGS inS. pseudocapsicum, which has great ornamental and pharmaceutical value, usingtobacco rattle virus(TRV) vectors. Two marker genes,PHYTOENE DESATURASE(PDS) andMg-chelatase H subunit(ChlH), were used to test the VIGS system inS. pseudocapsicum. The photobleaching and yellow-leaf phenotypes of the silenced plants were shown to significantly correlate with the down-regulation of endogenousSpPDSandSpChlH, respectively (P ≤ 0.05). Moreover, the parameters potentially affecting the efficiency of VIGS inS. pseudocapsicum, including the Agrobacterium strain and the inoculation method (leaf syringe-infiltration, sprout vacuum-infiltration and seed vacuum-infiltration), were compared. The optimized VIGS parameters were the leaf syringe-infiltration method, the Agrobacterium strain GV3101 and the growth of agro-inoculated plants at 25°. With these parameters, the silencing efficiency ofSpPDSandSpChlHcould reach approximately 50% inS. pseudocapsicum. Additionally, the suitability of various reference genes was screened by RT-qPCR using three candidate genes, and the results demonstrated that glyceraldehyde 3-phosphate dehydrogenase (GAPDH) can serve as a suitable reference for assessing the gene expression levels of VIGS systems inS. pseudocapsicum. The proven application of VIGS inS. pseudocapsicumand the characterization of a suitable reference gene in the present work will expedite the functional characterization of novel genes inS. pseudocapsicum.