bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low Food and Nutrition Literacy (FNLIT): A barrier to dietary diversity and nutrient adequacy in school age children
Authors: Doustmohammadian Azam , Omidvar Nasrin , Mohammadi Nastaran Keshavarz , Eini-Zinab Hassan , Amini Maryam , Abdollahi Morteza , Amirhamidi Zeinab , Haidari Homa 
Published: September 2019

Abstract
Background: Increasing prevalence of overweight/obesity in children and adolescents over the past two decades has made it a public health concern. Knowledge, skills and critical decision making about food choices and dietary intake, known as food and nutrition literacy (FNLIT) could be one of the keys to improving the outcomes of future interventions in this area. This study aims to assess the relationship between FNLIT and dietary diversity and nutrient adequacy in school-age children in Iran.Methods: This cross-sectional study was undertaken on 803 Primary school students aged 10-12 years in Tehran, Iran. Socio-economic and household food security characteristics, as well as three 24-hour dietary recalls (two week-days and one weekend) were collected through interviewing students and their mothers/caregivers. FNLIT was measured by a self-administered locally designed and validated questionnaire. Number of servings from food groups and diet diversity score, as well as nutrient adequacy were calculated and compared with recommendations. The association between dietary quality factors and FNLIT were evaluated by logistic regression analysis. Results: Students with low FNLIT were less likely to meet daily recommended portion of vegetable (OR=2.83, 95% CI=1.12-7.17), meats (OR=2.37, 95% CI=1.01-5.55) and fruits (OR=2.42, 95% CI=1.38-4.25) (after adjusting for confounding factors, including demographics, Socioeconomics, physical activity, calorie intake and food security). Moreover, low FNLIT subscales were associated with higher odds of low diversity of fruits (OR=3.82, 95% CI=1.01-14.42), dairies (OR=19.5, 95% CI=2.09-182.38), and meats (OR=2.4, 95% CI=1.31-4.40). low FNLIT and its subscales were associated with odds of lower level of NAR of protein (OR=2.02, 95% CI=1.02-8.95), calcium (OR=2.2, 95% CI=1.16-4.49), and vitamin B3 (OR=3.65, 95% CI=1.05-12.69), as well as probability of lower level of MAR (OR=2.91, 95% CI=1.03-8.23, OR=3.12, 95% CI=1.38-7.05), and NAR of vitamin B9 (OR=2.98, 95% CI=1.04-8.51), and odds of lower level of NAR of vitamin B6 (OR=2.30, 95% CI=1.10-4.83). Conclusion: Improving FNLIT in children may help to improve their eating habits and dietary quality for the benefits of good health.
Prevalence and Risk Factors of Active Trachoma among Rural Preschool Children in Wadla District, Northern Ethiopia: A Community Based Cross-Sectional Study
Authors: Kassaw Mesfin Wudu , Abebe Ayele Mamo , Tegegne Kirubel Dagnaw , Getu Mikiyas Amare , Bihonegn Woldemichael Tadesse 
Published: September 2019

Abstract
Background፡ Trachoma is a neglected eye problem and primary cause of preventable corneal blindness. In endemic areas, initial infection occurs in early childhood, and recurrent infection progress to scarring and blindness. In the past four decades, GET2020 initiative eliminated Trachoma from developed countries through enhancements of hygiene and sanitation but still a problem of developing countries. Studies and reports also indicated the presence of high prevalence of Trachoma in Ethiopia and in the study area. Thus, the purpose of this study is to assess the prevalence and risk factors of active trachoma among rural preschool children in Wadla district, Ethiopia. Methods: A community based cross-sectional study design was considered to gather data from 583 children using sample size determination, but 596 children were screened for signs of active trachoma because of the sampling procedure nature, cluster sampling technique. Wadla district has 150 rural villages, which are similar in topography and socio-demographic status. Based on rule of thumb 30 villages (clusters) were included for the data collection. An interview on socio-demographic data were collected by health informatics professionals using structured interview questioners, which were prepared through reviewing previous literatures and pretested in Meket Woreda. Eye examination was performed by Integrated Eye Care Workers who trained for one month for the purpose of trachoma screening by Carter center-Ethiopia. Results - The prevalence of active trachoma among rural pre-school children in Wadla district was 130 (21.8%). Regarding risk factors, poor economic status (AOR (95% CI), (3.8 (1.3-11.4), being 37- 48 months old (AOR (95% CI), (4.2 (1.5-12.0), thatched house roof (AOR (95%CI), (4.4 (1.4-13.6), presence of fly in nearby home (AOR (95% CI), 4.6 (2.1-9.9), once weekly face washing frequency (AOR (95% CI), 8.6 (2.5-29.3), unwashed face for longer than a week (AOR (95% CI), 10.6 (2.9-37.7), not using soap (AOR (95% CI), 4.5 (1.8-11.3), and absence of latrine (AOR (95% CI), 5.1 (2.0-12.9) have association with active trachoma. Conclusion: Environmental factors weigh other factors and this could capture the intention of policy makers to emphasize on the environmental components like sanitation including face cleanness to decrease the prevalence of trachoma
Reactive adsorption of Safranin O: surface – pore diffusion modeling and degradation study
Authors: Sharma Komal , Vyas Raj K. , Singh Kailash , Dalai Ajay K. 
Published: September 2019

AbstractGranular activated carbon was doped with iron (Fe-AC) and was used to study the removal of Safranin O (SO) using the Fe-AC/H2O2 system for reactive adsorption and Fe-AC for adsorption. Fe-AC and H2O2 doses were optimized to obtain maximum removal of SO. Maximum removal was found to be 96.1% after 5 h using 1.0 g/L Fe-AC and 5.0 mM hydrogen peroxide doses for 10 mg/L initial SO concentration. Kinetic study suggested the suitability of the pseudo-first-order model for reactive adsorption. The Langmuir isotherm explained well the sorption of SO onto Fe-AC. Parallel-pore-reactive adsorption model was applied and validated. By fitting the experimental data to the model, it is observed that the surface reaction rate coefficient, kr, was found to be five times that of the apparent rate constant, kapp. Parameters such as the external liquid film mass transfer coefficient, macro-pore and micro-pore diffusivities were estimated by regression analysis. Pore diffusion and surface reaction were found to be rate controlling for adsorption and reactive adsorption, respectively. An oxidative degradation of SO took place via hydroxylation and ring cleavage processes.
Doğrudan Yabancı Yatırım Girişlerinde Açıklanmış Karşılaştırmalı Üstünlük Analizi
Authors: Kılıçarslan Zerrin 
Published: September 2019

Rekabet gücü yüksek olan
sektörleri belirlemek için Balassa endeksi olarak da bilinen açıklanmış
karşılaştırmalı üstünlük (RCA) endeksi kullanılmaktadır. Bu endeksten hareketle doğrudan yabancı
yatırım çekmek üzere hedef sektörleri belirlemek veya doğrudan yabancı yatırım
için konumların karşılaştırmalı üstünlüğünü analiz etmek için kullanılacak bir
yöntem olarak doğrudan yabancı yatırımda açıklanmış karşılaştırmalı üstünlük
endeksi Loewendahl ve Barklie (2018) tarafından geliştirilmiştir. Bu çalışmada
Türkiye’nin ve OECD ülkelerinin doğrudan yabancı yatırımlardaki açıklanmış
karşılaştırmalı üstünlüklerinin sektörel olarak belirlenmesi amaçlanmıştır. Bu
amaçla Loewendahl ve Barklie (2018) tarafından geliştirilen endeksi
kullanılmıştır. Türkiye’nin doğrudan yabancı yatırımlarda açıklanmış
karşılaştırmalı üstünlüğe sahip olduğu sektörler belirlenmiştir. RCA-FDI endeksi
değerleri 2013 ve 2017 yılları için ayrı ayrı hesaplanmış ve Türkiye’nin
doğrudan yabancı yatırımlardaki açıklanmış karşılaştırmalı üstünlüklerindeki
değişim açıklanmıştır. Ayrıca OECD ülkeleri için temel ekonomik faaliyet
alanlarında endeksi hesaplanmıştır. Türkiye için hesaplanan endeksi değerlerine
göre ana faaliyet alanları içerisinde “tarım, ormancılık ve balıkçılık”
sektöründe güçlü karşılaştırmalı üstünlük, “imalat” sektöründe zayıf
karşılaştırmalı üstünlük, “elektrik, gaz, buhar ve iklimlendirme temini”nde
güçlü karşılaştırmalı üstünlük, “su tedariki, kanalizasyon, atık yönetimi ve
iyileştirme faaliyetleri”nde zayıf karşılaştırmalı üstünlük, “inşaat”ta zayıf
karşılaştırmalı üstünlük ortaya çıkmıştır. Bununla birlikte “hizmetler”
sektöründe ise rekabet avantajı bulunmamaktadır. Türkiye’nin en güçlü
karşılaştırmalı üstünlüğünün olduğu sektörler “kütüphaneler, arşivler, müzeler
ve diğer kültürel faaliyetler” ve “kara taşımacılığı ve boru hatları taşımacılığı”dır.
OECD ülkelerinde güçlü karşılaştırmalı üstünlüğe sahip olan ülke sayısının en
fazla olduğu sektör “tarım, ormancılık ve balıkçılık”tır. Karşılaştırmalı
dezavantaja sahip olan ülke sayısının en fazla olduğu sektör ise “madencilik ve
taşocakçılığı”dır. “İmalat” sektöründe ise hiçbir ülke güçlü ve orta
karşılaştırmalı üstünlüğe sahip bulunmamaktadır.
Drug Repurposing Screen Identifies Novel Classes of Drugs with Anticancer Activity in Mantle Cell Lymphoma
Authors: Han Chengwu , Yu Xueying , Zhang Chunxia , Cai Ying , Cao Yongyue , Wang Sijie , Shen Jun 
Published: September 2019

Aim and Objective:
Mantle Cell Lymphoma (MCL) is typically an aggressive and rare
disease with poor prognosis, therefore new effective therapeutics are urgently needed. Drug
repurposing for cancer treatment is becoming increasingly more attractive as an alternative
approach to discover clinically approved drugs that demonstrate antineoplastic effect. The
objective of this study was to screen an approved drug library and identify candidate compounds
with an antineoplastic effect in MCL cells using High-Throughput Screening (HTS) technique.

Materials and Methods:
Using the HTS technique, nearly 3,800 clinically approved drugs and
drug candidates were screened in Jeko and Mino MCL cell lines. We also demonstrated the
selectivity window of the candidate compounds in six normal cell lines. Further validations were
performed in caspase-3/7 apoptosis assay and three-dimensional (3D) multicellular aggregates
model using Z138 cell line.

Results:
We identified 98 compounds showing >50% inhibition in either MCL cell line screened,
they were distributed across eight unique therapeutic categories and have different mechanisms of
action (MOA). We selected alisertib, carfilzomib, pracinostat and YM155 for further validation
based on their antiproliferative activity in two MCL cell lines, selectivity to normal cell lines, and
drug developing stages in terms of clinical research. Alisertib and carfilzomib showed
antiproliferative effect on MCL cell with EC50 = 6 nM and >100-fold selectivity to normal cell
lines, especially for alisertib which demonstrated >1000-fold selectivity to 5 out of 6 normal cell
lines. Pracinostat and YM155 had potency of 11 and 12 nM in MCL cell with >20-fold selectivity
to normal cell lines. All four compounds had been tested in caspase-dependent apoptosis assay. We
further validated and demonstrated their anti-MCL effect on cell proliferation and (3D)
multicellular aggregates model using Z138 cell line.

Conclusion:
This is the first study to examine such a large library of clinically approved
compounds for the identification of novel drug candidates for MCL treatment, the results could be
rapidly translated into clinical practice in patients with MCL.
Clinical Features of Systemic Lupus Erythematosus in Tunisian Males
Authors: Sayhi Sameh , Achour Tayssir B. , Mezri Sameh , Hamdi Mohamed S. , Nour Gueddiche , Bilel Arfaoui , Abdelhafidh Nadia B. , Ajili Faida , Louzir Bassem 
Published: September 2019

Purpose:
Systemic Lupus Erythematosus (SLE) in males is rare. Clinical and biological
features, as well as, the outcome may differ comparatively to female patients. The purpose of our
study is to define these clinical and biological features in Tunisian male patients presenting SLE.

Methods:
A mono-centric, retrospective and descriptive study of 96 patients followed for SLE out
of which 21 are males. A comparative study was then performed between male and female patients
groups.

Results:
Sex-ratio female/male was 3.6/1, the average age at diagnosis of SLE was 37.8±14 years.
The most frequently noted clinical manifestations were: skin involvement (81%), renal involvement
(71.4%) and joint damage (66.7). We observed a significant difference in clinical features between
male and female patients (21 males and 76 females): renal failure (52% vs. 71.4%), serositis
(23.8% vs. 2.7%), peripheral neuropathy (19% vs. 4%) and lung interstitial disease (14.3% vs.
1.3%). No significant difference was found in the positivity of serum antibodies between the two
groups. Fifteen male patients (71.4%) had a SLEDAI score greater than or equal to 11, referring to
high/very high disease activity. Out of the 32 patients who developed infectious complications during
the course of the disease, 11 were male (52.4% of males). Concerning the male group, complete
remission was observed in 10 patients (47.6%), while 10 others presented persistent sequella. We
observed one death in the male group secondary to infective acute respiratory failure.

Conclusion:
SLE in male patients is rare and associated with poor prognosis. Disparity was observed
in clinical and biological features as well as outcome in the different studies. In our study,
we concluded that male lupus is more severe.
Design and Molecular Docking Studies of Some 2,3 Di-Substituted Quinazolin-4-One Analogues Against Staphylococcus aureus UDG
Authors: Bhavesh Amrute B. , Rakesh Amrutkar D. , Santosh Tambe R. 
Published: September 2019

Background:
In this present investigation, some 2, 3 disubstituted-quinazolin-4-one derivatives
are designed and docked against chain A and chain B of (3WDF) receptor.

Methods:
The heterocyclic fused rings quinazolinone have drawn a great attention owing to their
expanded applications in the field of pharmaceutical chemistry. The diverse range of molecules
with quinazoline/quinazolinone moieties have been reported to exhibit a broad spectrum of biological
activities.

Results:
The results designate that the quinazolinone ring forms hydrophobic and hydrogen bond
contacts with ASN 127 A, ALA 126 A, and SER 83 B, SER 183 B amino acid residue.

Conclusion:
: Molecular docking is safe and straightforward to use tool which facilitates in investigating,
interpreting, enplaning and identification of molecular properties using 3D structures.
Pembrolizumab-Induced Seronegative Arthritis and Fasciitis in a Patient with Lung Adenocarcinoma
Authors: Kobak Senol 
Published: September 2019

Background:
Immune checkpoint inhibitors (CPIs) are new promising anti-cancer drugs that
block negative costimulation of T-cells leading to an enhanced anti-tumor immune response. Pembrolizumab,
an a monoclonal antibody, targeting the programmed cell death protein 1 (PD-1) pathway. CPIs
have been associated with a number of immune-related adverse events (AEs), including musculoskeletal
and rheumatic disease.

Objective:
To present a case with lung adenocarcinoma treated with pembrolizumab, which developed inflammatory
arthritis and fasciitis.

Case Report:
A 73-year-old male patient was referred to the rheumatology outpatient clinic with complaints
of pain in the pretibial area, pain and swelling in both ankles joints and the right fırst metacarpophalangeal
(MCP) joint. Three months ago he had diagnosed with lung adenocarcinoma and pembrolizumab was started.
Locomotor system complaints were started after receiving two infusions of pembrolizumab. Physical
examination revealed both ankle arthritis, mild edema in the pretibial region, tenderness in the muscles and
arthritis in the right fırst MCP joint. Laboratory examinations showed mild acute phase reactants elevation.
Lower extremity MRI showed diffuse edema in both gastrocnemius muscle and fascia, compatible with
fasciitis. Pembrolizumab-related fasciitis and seronegative arthritis were diagnosed. Low dose corticosteroid
was started and a significant regression was observed in the patient's complaints.

Conclusion:
Inflammatory myositis with fasciitis and inflammatory arthritis in lower extremities appears to
be a new adverse effect of pembrolizumab therapy.
ANTI-INFLAMMATORY EFFECT OF NIGELLA SATIVA OIL ON CHEMORADIATION-INDUCED ORAL MUCOSITIS IN PATIENTS WITH HEAD AND NECK CANCERS
Authors: AMEEN HAZHA ABDULLAH MOHAMMED , MOHAMMED MOHAMMED OMER , KHADIJA MUHAMED AHMED  , REBAZ HAMA-GAREB ALI  , KAMAL AHMED SAEED  , SAAD ABDULRAHMAN HUSSAIN  
Published: September 2019

Objective: Oral mucositis (OM) is a common treatment-induced toxicity in patients undergoing radiation or chemoradiation for head and neck cancers (HNC). The study aims to evaluate the anti-inflammatory effect of Nigella sativa (NS) oil in radiation-or chemoradiation-induced OM in HNC patients.
Methods: From Forty HNC patients were randomized to two groups, each of 20 patients. The first group was treated with NS oil mouthwash five times daily, while the second group was treated with the Magic mouthwash and served as a control. All patients received radiotherapy (RT) (60-70 Gy) in 30-35 fractions over 6-7 w with or without chemotherapy. Patients were evaluated once per week to estimate the severity and duration of OM and the salivary levels of IL-6 and TNF-α.
Results: 70% of patients were men and the commonest tumor locations were larynx (47.5%) and pharynx (22.5%) classified as stages III or IV. NS oil significantly reduces RTOG grade and OM severity after 3-4 w of RT, attenuates the elevation in salivary IL-6 and TNF-α production after 3-5 w.
Conclusion: Nigella sativa oil mouthwash have a potential anti-inflammatory activity that may be beneficial in minimizing or preventing radiation-or chemoradiation-induced oral mucositis in patients with head and neck cancer.
Santé sexuelle et usages du Web : que cherchent à savoir les jeunes femmes sur internet?
Authors: Lang Marie-Eve 
Published: September 2019

Background Despite a growing number of studies on young people, the internet, and sexuality, not much is known on young women’s Web searches regarding sexuality, and even less so on the context of their queries.Analysis Based on an innovative “private” blog method combined with in-depth interviews, our study sought to determine what teenage girls and young women ages 17 to 21 are searching for on the Web—as well as their motivations.Conclusions and implications Results show that the participants use the internet to gather information on a wide variety of sexual topics, often to calm their anxiety about social norms—especially when the nature of their worries is taboo.
Cheating the Network: How Gamers Play the Infrastructure
Authors: Willett Sean , Hogan Mél 
Published: September 2019

Background This article looks at how video game players interact directly with the infrastructure and networks that support digital games. To win, players are no longer simply “cheating the game,” as with traditional behaviour considered deceptive or outside of the established rules, but are instead “cheating the network.” Analysis This distinction between these two types of cheating is important, and should be considered separate types of player interaction. “Cheating the network” is a new type of public engagement with network technology—one that runs counter to conventional views of a transparent, invisible media infrastructure. Conclusion and implications By examining “cheating the network” separately from traditional forms of cheating in digital games, it is possible to reframe these player/game interactions as player/infrastructure interactions and view them through a critical lens of materiality.
Decolonizing Data Relations: On the Moral Economy of Data Sharing in Palestinian Refugee Camps
Authors: Halkort Monika 
Published: September 2019

Background This article interrogates the critical intersection of measurement, datafication, and value extraction in humanitarian settings, drawing on empirical examples of data sharing in Palestinian camps in Lebanon.Analysis Building on decolonial theory and post-humanist perspectives, the article offers a critical rereading of the moral economy as historically situated transversal practice and explores how the nonlinear transition of lived and embodied knowledge into and out of data (re)configures the calculus of reciprocity, justice, and fairness in the anticolonial struggle of Palestinians.Conclusion and implications The article introduces the concept of “ethico-political substance” to problematize the historical entanglement of social ontologies, coloniality, and power-knowledge and to show a constitutive split between data and its subjects, which continues to undermine the political possibilities of datafication to this day.
Welfare Fraud 2.0? Using Big Data to Surveil, Stigmatize, and Criminalize the Poor
Authors: Dobson Kathy 
Published: September 2019

Background This article examines the discourse around the digital surveillance of those living on social assistance by analyzing two digital “anti-fraud” tracking tools: Ontario’s Social Assistance Management System and Australia’s BasicsCard system.Analysis Digital surveillance and big data analytical processes embedded in the utilization of digital “anti-fraud” tracking tools tend to operate outside of democratic processes, outpace ethical considerations, and even create and reinforce social divisions and inequality.Conclusion and implications Despite the claim that these software programs make about saving taxpayers’ money and assisting those in need more effectively, these digital tools adversely affect the people they are supposed to help and, worse, stigmatize and criminalize those who live in poverty.
Data Corruption: The Institutional Cultures of Data Collection and the Case of a Crime-Mapping System in Latin America
Authors: Barreneche Carlos 
Published: September 2019

Background This article is a case study about a surveillance system deployed in a Latin American city that collects and analyses geocoded historical crime data in order to identify crime hot spots. Analysis The case study focuses on the adoption of this technology by data collectors and the institutional cultures that mediate its workings. The article documents the conflicting adjustment strategies carried out by low-level police officers when the same crime data that they help to produce are operationalized as labour performance indicators. Conclusion and implications Drawing from scholarship in the field of critical data studies, this work situates the practices of data generation within institutional power relations to shed light on the particular politics at play in data-driven policing systems in the Latin American context.
Cirurgia Parendodôntica: quando e como fazer
Authors: Orso Vanderlê De Arlete , Sant'Ana Filho Manoel 
Published: September 2019

A cirurgia parendodôntica associada a endodontia é a opção de tratamento quando não se consegue eliminar o agente etiológico do processo inflamatório periapical de maneira conservadora, ou seja, pelo tratamento endodôntico, na busca do reparo. Entretanto, há uma diversidade de técnicas descritas, sendo difícil ao iniciante definir qual está indicada e quando. Nesta revisão de literatura foram encontrados vários métodos cirúrgicos de abordagem apical, com indicações distintas, sendo a apicetomia e a obturação retrógrada os mais visados para pesquisa. Apesar dos avanços nesta área, com inovações sendo introduzidas, como é o caso do Laser,
várias são as causas de fracasso da cirurgia apical. Diante disto, propõe-se analisar os diferentes métodos descritos através de uma revisão literária, concluindo-se que todos são válidos desde que o objetivo proposto seja alcançado, ou seja: a remoção do agente causal.