bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Cigarette Smoking at the Time of Surgery on Postoperative Outcomes in Patients With Femoroacetabular Impingement: A Matched-Pair Cohort Analysis
Authors: Cancienne Jourdan , Kunze Kyle N. , Beck Edward C. , Chahla Jorge , Suppauksorn Sunikom , Nho Shane J. 
Published: April 2019

Background: There is literature on the association between smoking in patients undergoing orthopaedic procedures and poor short-term outcomes. However, there are few data on smoking as an independent predictor of midterm outcomes in patients undergoing hip arthroscopic surgery for femoroacetabular impingement (FAI). Purpose: To evaluate 2-year postoperative outcomes in patients undergoing hip arthroscopic surgery for FAI in current smokers compared with an age- and body mass index (BMI)–matched group with no smoking history. Study Design: Cohort study; Level of evidence, 3. Methods: Consecutive patients undergoing primary hip arthroscopic surgery for FAI between June 2012 and January 2016 were screened for smoking habits. Exclusion criteria included revision or bilateral surgery, dysplasia, and less than 2-year follow-up. Forty current smokers at the time of surgery were matched 1:2 by age and BMI to patients with no smoking history. Outcome measures included the Hip Outcome Score (HOS)–Activities of Daily Living (ADL), HOS–Sports-Specific Subscale (SSS), modified Harris Hip Score (mHHS), and visual analog scale (VAS) for pain and satisfaction. Minimal clinically important difference (MCID) and patient acceptable symptom state rates were calculated for all patients. Results: All patients demonstrated significant improvements in all outcome measures ( P < .001). Current smokers experienced inferior postoperative HOS-ADL (80.4 vs 89.1, respectively; P = .013) and HOS-SSS (65.8 vs 75.6, respectively; P = .046) scores and greater VAS pain scores (3.2 vs 1.8, respectively; P = .011) than nonsmokers. Current smoking was correlated with inferior HOS-ADL ( r = –0.27, P = .003) and HOS-SSS ( r = –0.18, P = .046) scores and greater VAS pain scores ( r = 0.26, P = .005). Controlling for age, sex, and BMI, smoking was a significant independent predictor of postoperative HOS-ADL (β = –8.7 [95% CI, –14.3 to –3.0]; P = .003), HOS-SSS (β = –9.8 [95% CI, –19.5 to –0.2]; P = .046), and VAS pain (β = 14.6 [95% CI, 4.4 to 23.7]; P = .005) scores. Current smokers had lower odds of achieving the MCID for the HOS-ADL (odds ratio, 0.31 [95% CI, 0.12-0.83]; P = .019) and mHHS (odds ratio, 0.31 [95% CI, 0.10-0.88]; P = .028). Conclusion: Current smokers had inferior postoperative HOS-ADL and HOS-SSS scores, increased pain, and lower odds of achieving the MCID for the HOS-ADL and mHHS at 2 years postoperatively than patients without any smoking history.
Chinese Systemic Lupus Erythematosus Treatment and Research Group (CSTAR) Registry XI: gender impact on long-term outcomes
Authors: Zhang S , Ye Z , Li C , Li Z , Li X , Wu L , Liu S , Zuo X , Zhu P , Wang Z , Wang Y , Wang Z , Zhao J , Wang Q , Tian X , Li M , Zeng X 
Published: April 2019

Objective The objective of this paper is to assess the role of gender on survival rate and causes of death and organ damage in systemic lupus erythematosus (SLE) patients in China from 2009 to 2015. Methods We conducted a multicenter cohort study to analyze the differences in outcome data between male and female SLE patients. A group of 1494 SLE patients who fulfilled the 1997 American College of Rheumatology SLE classification criteria were enrolled in the Chinese Systemic Lupus Erythematosus Treatment and Research Group (CSTAR) registry from April 2009 to February 2010. All enrolled patients were followed up at least once per year from 2009 to 2015. For patients who could not attend the outpatient clinic, follow-up was conducted by telephone interview. We collected demographic data, clinical manifestations and damage scores (System Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI)). Survival rates were evaluated using the Kaplan-Meier method. Results This study included 1352 women and 142 men. The five-year survival rates were 92.0% for men and 97.6% for women. The survival rates of males were significant lower than for females ( p = 0.019). Male patients received methylprednisolone pulse therapy and cyclophosphamide significantly more than female patients ( p = 0.010). During follow-up, 12 male patients and 66 female patients died. The most common cause of death was infection (41.7%) for men and active SLE disease (27.3%) for women. At the end of the study, the major accumulated organ damages included renal (8.5%) and musculoskeletal (7.7%), and nervous system (5.6%) for men and renal (8.8%) and musculoskeletal (6.7%) for women. There were no significant differences in SDI scores between the two groups at baseline and at the end of the study. Conclusions Male SLE patients had lower survival rates than female patients. Male patients received more methylprednisolone pulse and cyclophosphamide therapy. The most common causes of death were infection for male patients and active SLE disease for female patients. The major accumulated organ damages were renal, musculoskeletal, and nervous system both for male and female SLE patients in China.
Destigmatized Group Intervention on Promoting Hope of Recovery: A Quasi-Experiment Study
Authors: Young Daniel K. W. , Ng Petrus Y. N. , Cheng Daphne 
Published: April 2019

Objective: This research project aims to evaluate the effectiveness of a destigmatized group intervention in promoting hope of recovery for adults with mental illness. Methods: A quasi-experimental research method was adopted. In addition to treatment as usual (TAU), the treatment group ( n = 36) participated in a 10-session destigmatized group intervention, which was based on cognitive behavioral therapy (CBT), while the control group ( n = 42) received TAU. Standardized assessment tools were used for outcome assessment at the pretreatment and posttreatment periods. Results: The 2 × 2 repeated measures analysis of covariance demonstrated that participants who participated in the destigmatized group intervention experienced significantly fewer self-stigma and more hope of recovery. Additionally, multiple linear regression showed that the reduction of self-stigma predicted the promotion of hope of recovery. Conclusions: This study supports the effectiveness of the destigmatized group intervention, suggesting the importance of reducing self-stigma for facilitating recovery for adults with mental illness.
Stability studies of two compounded solutions potentially used in tumor lysis syndrome
Authors: Stawny Maciej , Gostyńska Aleksandra , Górecka Alina , Mańkowska Dorota , Kołodziej Izabela , Jankowiak-Gracz Hanna , Ogrodowczyk Magdalena 
Published: April 2019

Objective The aim of the study was to determine the stability of two non-commercially produced solutions: 1.68% sodium bicarbonate in 5% glucose (BIC solution) and 1.6% calcium chloride in 0.9% sodium chloride (CAL solution), which can be used to treat tumor lysis syndrome. One of the ways to treat the tumor lysis syndrome is to irrigate patients, alkalinize the urine through the supply of BIC solution or continuous hemodialysis with regional citrate anticoagulation, using a CAL solution. Method The study took place in two independent hospital pharmacies. Fifty samples of each solution were prepared under aseptic conditions, then the concentration of sodium and calcium ions was determined and microbiological purity tests were carried out. The tests were performed on the day of sample preparation and after seven days of storage at 4 ± 1℃. Results The obtained results showed that applied preparation method was precise and accuracy. The average concentration of sodium ions in BIC solutions ranged from 187.7 to 185.26 mmol/L on 1st and 7th day, respectively. The average concentration of calcium ions in CAL solution ranged from 68.92 to 68.80 mmol/L on 1st and 7th day, respectively. None of the samples were microbiologically contaminated. Conclusion Studied solutions for infusion were characterized by good chemical and microbiological stability when prepared in a clean room and stored at 4 ± 1℃.
CT characterisation of feline adrenal glands
Authors: Mallol Claudia , Altuzarra Raúl , Espada Yvonne , Tobón Restrepo Mauricio , Serrano Emmanuel , Novellas Rosa 
Published: April 2019

Objectives The objectives of this study were to describe the CT characteristics of the adrenal glands in healthy cats, to provide normal reference biometry for adrenal gland size and attenuation values, and to investigate the association with age, sex, laterality and body weight. Methods Retrospective evaluation of 30 CT studies of healthy adult cats recruited from September 2013 to July 2015 was performed. Healthy cats >1 year of age were included based on the absence of clinical signs, unremarkable physical examination, normal results of the complete blood count, biochemical profile, feline immunodeficiency virus, feline leukaemia virus and Bartonella species infection tests. The relationship between gland biometry (size and attenuation values) and the age, sex, laterality and body weight of cats were tested by two-way ANOVA. The intraclass correlation coefficient was assessed and mean, SD, range and reference interval provided. Results Twenty-seven cats were included. Bilobed, arrowhead and oval adrenal gland shape patterns were recognised, the first being most common. No statistically significant differences were observed between the biometric parameters (length, height and attenuation values) and age, sex, laterality or body weight of the cats. Regarding the width of the adrenal glands, there was a statistically significant effect of sex and laterality. The length (11.6 ± 2.1 mm) and height (6.1 ± 1.3 mm) were the most consistent biometrical parameters to describe adrenal glands. Conclusions and relevance Adrenal gland shape, size and attenuation CT data of healthy feline patients are provided in this study, as well as normal reference intervals for morphometric characterisation based on adrenal length and height.
non-arthroplasty iliopsoas impingement in athletes: a narrative literature review
Authors: Andronic Octavian , Nakano Naoki , Daivajna Sachin , Board Tim N , Khanduja Vikas 
Published: April 2019

Introduction: Iliopsoas impingement occurs secondary to a tight iliopsoas tendon that causes impingement during movement. This review presents current aspects regarding the diagnosis of iliopsoas impingement and also exposes the readers to the possible anatomic and clinical variations together with the available treatment options. Methods: We conducted a narrative literature review with regard to non-arthroplasty iliopsoas impingement. Results: Iliopsoas impingement is characterised by a distinct pattern of labral pathology, with anteriorly localised labral damage, that does not extend to the anterosuperior portion of the acetabulum. Anterior groin pain and intermittent catching, snapping or popping of the hip are common symptoms. Non-specific focal tenderness is often found over the iliopsoas tendon at the level of the anterior aspect of the joint. The ‘C-sign’ and Impingment test are usually positive. Dynamic ultrasonography is also useful for confirming the diagnosis. Initial management of painful iliopsoas impingement should be conservative. When patients continue to have pain, an ultrasound-guided injection can provide relief and predict the response to the surgical release. For patients who have recurrent pain after local injection of steroids, arthroscopic release has shown to achieve effective results. Conclusions: Although different treatment options for iliopsoas impingement are emerging, the current standard of therapy is conservative followed by an arthroscopic tenotomy if necessary. Young adult hip surgeons should always keep this differential in mind in a patient presenting with groin pain and mechanical symptoms.
Myoepithelial Cell Carcinoma of the Oral Tongue: Case Report and Review of the Literature
Authors: Nicholas Robert G , Hanson Josh A , Meiklejohn Duncan A 
Published: April 2019

Background: Myoepithelial cell carcinoma is a rare malignant neoplasm of salivary gland origin that typically presents in the parotid gland and minor salivary glands. It has been described previously in head and neck sites such as buccal mucosa, alveolar ridge, and base of tongue. Methods: A 55-year-old man presented with 30 years of right-sided tongue pain and 10 years of gradually worsening ulceration. Physical examination demonstrated a 2.5 cm ulcerative lesion of the anterior right oral tongue. An initial biopsy was consistent with moderately to poorly differentiated squamous cell carcinoma. Imaging included a positron emission tomography (PET)/computed tomography (CT) scan that demonstrated the right tongue lesion as well as hypermetabolic right level II adenopathy. The patient underwent surgical excision of the right tongue, upper aerodigestive tract endoscopy, and a bilateral supraomohyoid neck dissection. The tongue defect was closed primarily. Results: Final pathology of the surgical specimen demonstrated myoepithelial cell carcinoma. All of the margins were free of tumor and no cervical lymph nodes showed metastasis. Immunohistochemistry demonstrated myoepithelial differentiation. The tumor did not show EWSR1 gene rearrangement on genetic testing, suggesting salivary gland origin. Multidisciplinary tumor board evaluation recommended no adjuvant therapy. The patient recovered well after surgery and nearly a year later is without evidence of recurrent or residual disease. Conclusions: We present the first reported case of myoepithelial cell carcinoma with primary origin in the oral tongue and review the available literature on this unusual tumor. We discuss the clinical, pathological, and immunohistochemical features and treatment of myoepithelial cell carcinoma.
Prevalence rates of substantiated and adjudicated ethics violations
Authors: Magiste Edward J 
Published: April 2019

Summary This exploratory study examined the ethics violation data from one state’s licensing agency over a 28-year period, from 1985 through 2013. This study used descriptive statistics and chi-square analysis of the data to determine occurrence and prevalence rates in 592 cases. Violations were grouped into seven categories, and days before a license complaint was filed were also examined: dates ranged from 8 years before a license was issued (fraud on license application) to 28 years after being licensed. There were 389 females and 203 males in the sample, with 430 holding a social work license, 160 professional counselors, and 2 marriage and family therapists. Findings Of the 592 substantiated and adjudicated cases, 221 related to violations involving licensure, with 169 of those failure to comply with continuing education requirements, and most of those by professionals who have been licensed 10 or more years. Additionally, 156 violations involved boundary crossings, only of which 36 involved sexual boundary violations. Of those involving sexual contact, 22 were by female professionals and 14 by males. An additional 12 cases involved inappropriate sexual relations, but these were unrelated to professional practice. Overall, sexually involved cases represented a little over 8% of the cases, while licensure issues represented 38% of the cases. Applications Understanding which violations occur with more frequency enables social work educators to incorporate understanding the ethics of the social work into academic curriculum. Further study enables the profession to look at both what occurs and how that impacts clients, workers, and the public trust.
Early results of carotid endarterectomy versus carotid stenting: Outcomes from a Mediterranean country
Authors: Castro-Ferreira Ricardo , Freitas Alberto , Sampaio Sérgio M , Dias Paulo G , Mansilha Armando , Teixeira José F , Leite-Moreira Adelino 
Published: April 2019

Introduction and objectives Which is the best carotid stenosis treatment remains a controversial issue. To present day, no study has compared the results of carotid artery stenting versus carotid endarterectomy in Portugal. We aim to provide real life numbers regarding the outcomes of both procedures in Portuguese public hospitals. Methods Every patient registered between 2005 and 2015 with the main diagnosis of carotid stenosis and submitted to carotid endarterectomy or carotid artery stenting was included. The information was obtained through the Central National Healthcare Administrative database, a mandatory registry for hospital refunding. Primary outcomes were hospital mortality and stroke. Patient demographics, comorbidities and hospital length of stay were also evaluated. Results The study included 6094 patients: 1399 were symptomatic (mention of prior stroke) and 4695 asymptomatic. Carotid artery stenting was performed on 22% of the symptomatic and 18% of the asymptomatic patients. In the symptomatic patients, the in-hospital mortality was significantly higher in those submitted to stenting (3.6% vs. 1.6% in carotid endarterectomy, p = 0.025). No significant differences in outcomes were observed in the asymptomatic group (mortality 0.9% vs. 0.8%, p = 0.852; stroke rate of 2.6% vs. 2.3%, p = 0.652 – carotid artery stenting vs. carotid endarterectomy). In both groups, there was an important increase in the proportion of stenting between 2005 and 2012, followed by a gradual decline until 2015. Conclusion Despite its increasing frequency, a higher early mortality was documented for CAS in symptomatic patients. No worse outcome was observed in asymptomatic patients.
A service improvement report of blood-borne virus screening in a high secure mental hospital
Authors: Strazds Pixy , Abdelrazek Tarek 
Published: April 2019

Background: Patients in a high secure hospital are a high-risk population for exposure to blood-borne viruses (BBV) because of previous lifestyles. Objective: This service improvement study intends to improve patients care by the Infection Prevention and Control Team (IPCT) coordinating the BBV screening and vaccination programme within the hospital. Methods: A retrospective review of patients’ notes in 2007 and 2016 was used. Results: The results show an increase in screening offered and screening undertaken from 2007 to 2016. It also identifies an increase in hepatitis B vaccination programmes completed. Discussion: The expansion of the IPC and Physical Healthcare Team appear to be associated with the increase of screening and vaccination rates.
Building the capacity – examining the impact of evidence-based public health trainings in Europe: a mixed methods approach
Authors: Serrano Natalicio , Diem Gunter , Grabauskas Vilius , Shatchkute Aushra , Stachenko Sylvie , Deshpande Anjali , Gillespie Kathleen N. , Baker Elizabeth A. , Vartinaien Erkki , Brownson Ross C. 
Published: April 2019

Objective: Since 2002, a course entitled ‘Evidence-Based Public Health (EBPH): A Course in Noncommunicable Disease (NCD) Prevention’ has been taught annually in Europe as a collaboration between the Prevention Research Center in St Louis and other international organizations. The core purpose of this training is to strengthen the capacity of public health professionals, in order to apply and adapt evidence-based programmes in NCD prevention. The purpose of the present study is to assess the effectiveness of this EBPH course, in order to inform and improve future EBPH trainings. Methods: A total of 208 individuals participated in the European EBPH course between 2007 and 2016. Of these, 86 (41%) completed an online survey. Outcomes measured include frequency of use of EBPH skills/materials/resources, benefits of using EBPH and barriers to using EBPH. Analysis was performed to see if time since taking the course affected EBPH effectiveness. Participants were then stratified by frequency of EBPH use (low v. high) and asked to participate in in-depth telephone interviews to further examine the long-term impact of the course ( n = 11 (6 low use, 5 high use)). Findings: The most commonly reported benefits among participants included: acquiring knowledge about a new subject (95%), seeing applications for this knowledge in their own work (84%), and becoming a better leader to promote evidence-based decision-making (82%). Additionally, not having enough funding for continued training in EBPH (44%), co-workers not having EBPH training (33%) and not having enough time to implement EBPH approaches (30%) were the most commonly reported barriers to using EBPH. Interviews indicated that work-place and leadership support were important in facilitating the use of EBPH. Conclusion: Although the EBPH course effectively benefits participants, barriers remain towards widely implementing evidence-based approaches. Reaching and communicating with those in leadership roles may facilitate the growth of EBPH across countries.
Remote ischemic preconditioning for elective endovascular intracranial aneurysm repair: a feasibility study
Authors: Mohammad Seyedsaadat Seyed , Rangel Castilla Leonardo , Lanzino Giuseppe , Cloft Harry J , Blezek Daniel J , Theiler Amy , Kadirvel Ramanathan , Brinjikji Waleed , Kallmes David F 
Published: April 2019

Objectives Remote ischemic preconditioning has been proposed as a possible potential treatment for ischemic stroke. However, neuroprotective benefits of the pre-procedural administration of remote ischemic preconditioning have not been investigated in patients undergoing an elective endovascular intracranial aneurysm repair procedure. This study investigated the safety and feasibility of remote ischemic preconditioning in patients with an unruptured intracranial aneurysm who undergo elective endovascular treatment. Methods In this single-center prospective study, patients with an unruptured intracranial aneurysm undergoing elective endovascular treatment with flow diverters or coiling were recruited. Patients received three intermittent cycles of 5 minutes arm ischemia followed by reperfusion using manual blood cuff inflation/deflation less than 5 hours prior to endovascular treatment. Patients were monitored and followed up for remote ischemic preconditioning-related adverse events and ischemic brain lesions by diffusion -weighted magnetic resonance imaging within 48 hours following endovascular treatment. Results A total of seven patients aged 60 ± 5 years with an unruptured intracranial aneurysm successfully completed a total of 21 sessions of remote ischemic preconditioning and the required procedures. Except for two patients who developed skin petechiae over their arms, no other serious procedure-related adverse events were observed as a result of the remote ischemic preconditioning procedure. On follow-up diffusion -weighted magnetic resonance imaging, a total of 19 ischemic brain lesions with a median (interquartile range) volume of 245 (61–466) mm3 were found in four out of seven patients. Conclusions The application of remote ischemic preconditioning prior to endovascular intracranial aneurysm repair was well tolerated, safe and clinically feasible. Larger sham-controlled clinical trials are required to determine the safety and efficacy of this therapeutic strategy in mitigating ischemic damage following endovascular treatment of intracranial aneurysms.