bluuebunny/crossref_metadata_2025_split huggingface dataset:
WHAT WAS CRITICAL HISTORY? A READING OF RICHARD SIMON'S HISTOIRE CRITIQUE DU VIEUX TESTAMENT
Authors: GABER GORAN 
Published: June 2018

ABSTRACTThe roots of our modern critical historical attitude are usually set in one of the following phenomena: (1) the Quarrel of the Ancients and the Moderns; (2) the establishment of historiography as a scientific discipline; and (3) the newly gained awareness of anachronism. However, these accounts either neglect the normative character of the above‐mentioned phenomena or operate with an a priori definition of “critical history,” which leads them to retrospectively attribute the concept of “critique” to historical realities that have not used the term to denote their attitude toward or their treatment of the past. Rather than starting from an a priori definition of what “critical history” is, I propose to inquire into what “critical history” was at the moment when it was first conceived as such—namely in Richard Simon's Histoire critique du Vieux Testament. I will begin by presenting Simon's conception of critique, which entailed: (a) a grammatical and philological treatment of the text in question; (b) a historical and cultural contextualization of this text; and (c) a specific type of judgment to be applied to what is written therein. Since this last aspect constitutes the key to understanding critique's attitude toward the past, I will, in the second part, focus my attention on the notion that plays a pivotal role in the exercise of “critical judgment,” that is, on the concept of tradition. Last, I will propose that since Simon's critical history does not seem to be completely autonomous in relation to its object, the roots of our modern call for normative autonomy vis‐à‐vis the past should be sought with the authors whom Simon opposed in his work, but from whom nonetheless he inherited the term critique: Protestant authors such as Scaliger, Casaubon, and Cappel.
From incipient island arc to doubly‐vergent orogen: A review of geodynamic models and sedimentary basin‐fills of southern Central America
Authors: Brandes Christian , Winsemann Jutta 
Published: June 2018

AbstractSouthern Central America is a Late Mesozoic/Cenozoic island arc that evolved in response to the subduction of the Farallón Plate beneath the Caribbean Plate in the Late Cretaceous and, from the Oligocene, the Cocos and Nazca Plates. Southern Central America is one of the best studied convergent margins in the world. The aim of this paper is to review the sedimentary and structural evolution of arc‐related sedimentary basins in southern Central America, and to show how the arc developed from a pre‐extensional intra‐oceanic island arc into a doubly‐vergent, subduction orogen. The Cenozoic sedimentary history of southern Central America is placed into the plate tectonic context of existing Caribbean Plate models. From regional basin analysis, the evolution of the southern Central American island arc is subdivided into three phases: (i) non‐extensional stage during the Campanian; (ii) extensional phase during the Maastrichtian‐Oligocene with rapid basin subsidence and deposition of arc‐related, clastic sediments; and (iii) doubly‐vergent, compressional arc phase along the 280 km long southern Costa Rican arc segment related to either oblique subduction of the Nazca plate, west‐to‐east passage of the Nazca–Cocos–Caribbean triple junction, or the subduction of rough oceanic crust of the Cocos Plate. The Pleistocene subduction of the Cocos Ridge contributed to the contraction but was not the primary driver. The architecture of the arc‐related sedimentary basin‐fills has been controlled by four factors: (i) subsidence caused by tectonic mechanisms, linked to the angle and morphology of the incoming plate, as shown by the fact that subduction of aseismic ridges and slab segments with rough crust were important drivers for subduction erosion, controlling the shape of forearc and trench‐slope basins, the lifespan of sedimentary basins, and the subsidence and uplift patterns; (ii) subsidence caused by slab rollback and resulting trench retreat; (iii) eustatic sea‐level changes; and (iv) sediment dispersal systems.
Quick vacuum drying of liquid samples prior to ATR‐FTIR spectral collection improves the quantitative prediction: a case study of milk adulteration
Authors: Ayvaz Huseyin , Temizkan Riza 
Published: June 2018

AbstractAttenuated total reflectance‐Fourier transform infrared (ATR‐FTIR) spectroscopy‐based prediction methods were previously shown to be a practical alternative to determine milk adulteration. However, milk in general contains high amount of water and infrared absorptions sourcing from water dominate the mid‐infrared spectrum of the milk, preventing the other key vibrations in fingerprint region from escalating. Therefore, we aimed at evaluating the efficacy of a 30‐s vacuum treatment on liquid milk aliquots prior to spectral collection and compare the results with no vacuum‐applied spectra. Overall, quick vacuum treatment approach led to better‐resolved peaks in the fingerprint region of the spectra compared with water‐dominated spectra of milk with no vacuum application. Considering the residual predictive deviation (RPD) values obtained, vacuum treatment has significantly improved the performance of the models in prediction indicating that quick vacuum approach would be beneficial if implemented for routine determination for milk adulteration.
Evaluation of the sensory and physical properties of meat and fish derivatives containing grape pomace powders
Authors: Mainente Federica , Menin Alessia , Alberton Angelica , Zoccatelli Gianni , Rizzi Corrado 
Published: June 2018

SummaryThe wine industry produces tons of pomace that, in a circular economy model, should be valorised. The phenols fraction of grape pomace represents a source of food colorants, but also of natural food preservatives. Furthermore, the pomace contains dietary fibre, unsaturated lipids, antioxidants and minerals that have been recognised as wholesome and technologically useful. The main drawback of using grape pomace is represented by its chemical and microbiological instability. Different authors proposed strategies to overcome these limitations, and different approaches for the use of grape pomace as an ingredient have been described. Here, we sum up the chemical and microbiological solutions for the stabilisation of grape pomace, describing the approaches used to transform this waste in a functional ingredient, and comparing the physiochemical characteristics of the resulting products. We further describe the studies concerning sensory aspects of the products by enriching animal fleshes with different pomace powder preparations.
Evaluation of Ion Torrent sequencing technology for rapid clinical human leucocyte antigen typing
Authors: Guerra Sandra G. , Chong Winnie , Brown Colin J. , Navarrete Cristina V. 
Published: June 2018

AbstractThe development of techniques to define the human leucocyte antigen (HLA) region has proven to be challenging due to its high level of polymorphism. Within a clinical laboratory, a technique for high‐resolution HLA typing, which is rapid and cost effective is essential. NGS has provided a rapid, high‐resolution HLA typing solution, which has reduced the number of HLA ambiguities seen with other typing methods. In this study, the One Lambda NXType NGS kit was tested on the Ion Torrent PGM platform. A total of 362 registry donors from four ethnic populations (Europeans, South Asians, Africans and Chinese) were NGS HLA typed across 9‐loci (HLA‐A, ‐B, ‐C, ‐DRB1,‐DRB345 ‐DQB1 and ‐DPB1). Concordance rates of 91%–98% were obtained (for HLA‐A, ‐B, ‐C, ‐DRB1, ‐DQB1 and ‐DPB1) when compared to historical PCR‐SSO HLA types, and the identification of uncommon alleles such as A*24:07:01 and C*04:82 were observed. A turnaround time of four days was achieved for typing 44 samples. However, some limitations were observed; primer locations did not allow all ambiguities to be resolved for HLA Class II where Exon I and IV amplification are needed (HLA‐DRB1*04:07:01/04:92, HLA‐DRB1*09:01:02/*09:21 and HLA‐DRB1*12:01:01/*12:10). This study has demonstrated high‐resolution typing by NGS can be achieved in an acceptable turnaround time for a clinical laboratory; however, the Ion Torrent workflow has some technical limitations that should be addressed.
ADHD symptoms and body composition changes in childhood: a longitudinal study evaluating directionality of associations
Authors: Bowling A. B. , Tiemeier H. W. , Jaddoe V. W. V. , Barker E. D. , Jansen P. W. 
Published: June 2018

SummaryBackgroundAttention‐deficit/hyperactivity disorder (ADHD) is linked to increased risk of overweight/obesity among children and adults. Studies have also implicated obesity as a risk factor for ADHD. However, no studies have evaluated bidirectional, longitudinal associations between childhood fat mass and ADHD symptom severity.ObjectivesWe investigate bidirectional associations between ADHD symptoms and measures of body composition between ages 1.5 and 9. We further examine effects of specific eating patterns linked to ADHD on associations between symptom severity and body composition.MethodsThe study utilized data from children (N = 3903) participating in the Generation R cohort (Netherlands). Children were enrolled at birth and retained regardless of ADHD symptoms over time. Cross‐lagged and change models examined bidirectional associations between body composition (body mass index/dual‐energy X‐ray absorptiometry) and ADHD symptoms at four time points in childhood.ResultsA child with a clinically concerning ADHD symptom z‐score two standard deviations above the mean at age 6 would be expected to experience about 0.22 kg greater fat mass gain measured via dual‐energy x‐ray absorptiometry between ages 6 and 9, even if they displayed healthy eating patterns (95% CI: 0.11 ‐ 0.28, p < 0.001). Conversely, fat mass at any age did not predict worse ADHD symptoms later.ConclusionsBeginning in early childhood, more ADHD symptoms predict higher fat mass at later ages. We did not find evidence of a reverse association. Based on these and prior findings, lifestyle counselling during treatment for children with a diagnosis of ADHD should be considered, even if they are diagnosed in early childhood and do not yet have a body mass index of clinical concern.
Plasmacytoid dendritic cell heterogeneity is defined by CXCL10 expression following TLR7 stimulation
Authors: Marsman Casper , Lafouresse Fanny , Liao Yang , Baldwin Tracey M , Mielke Lisa A , Hu Yifang , Mack Matthias , Hertzog Paul J , de Graaf Carolyn A , Shi Wei , Groom Joanna R 
Published: June 2018

AbstractPlasmacytoid dendritic cells (pDCs) play a critical role in bridging the innate and adaptive immune systems. pDCs are specialized type I interferon (IFN) producers, which has implicated them as initiators of autoimmune pathogenesis. However, little is known about the downstream effectors of type I IFN signaling that amplify autoimmune responses. Here, we have used a chemokine reporter mouse to determine the CXCR3 ligand responses in DCs subsets. Following TLR7 stimulation, conventional type 1 and type 2 DCs (cDC1 and cDC2, respectively) uniformly upregulate CXCL10. By contrast, the proportion of chemokine positive pDCs was significantly less, and stable CXCL10+ and CXCL10− populations could be distinguished. CXCL9 expression was induced in all cDC1s, in half of the cDC2 but not by pDCs. The requirement for IFNAR signaling for chemokine reporter expression was interrogated by receptor blocking and deficiency and shown to be critical for CXCR3 ligand expression in Flt3‐ligand‐derived DCs. Chemokine‐producing potential was not concordant with the previously identified markers of pDC heterogeneity. Finally, we show that CXCL10+ and CXCL10− populations are transcriptionally distinct, expressing unique transcriptional regulators, IFN signaling molecules, chemokines, cytokines, and cell surface markers. This work highlights CXCL10 as a downstream effector of type I IFN signaling and suggests a division of labor in pDCs subtypes that likely impacts their function as effectors of viral responses and as drivers of inflammation.
Lessons learnt from local real‐life experience with idarucizumab for the reversal of dabigatran
Authors: Brennan Yvonne , Favaloro Emmanuel J. , Pasalic Leonardo , Keenan Hayley , Curnow Jennifer 
Published: June 2018

AbstractBackgroundIdarucizumab is a specific antidote for the direct thrombin inhibitor oral anticoagulant dabigatran etexilate. It has been used with increasing frequency in Australia since it was granted Therapeutic Goods Administration approval in October 2016.AimsTo assess idarucizumab usage, effect on coagulation parameters and clinical outcomes in patients who received idarucizumab in Western Sydney Local Health District (WSLHD).MethodsA retrospective audit was conducted of all patients who received idarucizumab in WSLHD between September 2015 and December 2017.ResultsOf the 23 patients who received idarucizumab, 17 (74%) had bleeding, and 6 (26%) required urgent surgery/procedure. Thrombin time (TT) or activated partial thromboplastin time (APTT, when TT not available) remained prolonged at 24 h post‐idarucizumab infusion in 10 of 20 (50%) patients. Renal impairment at admission was associated with prolonged TT/APTT at 24 h (P = 0.02). Of the six (26%) patients who died during hospital admission, five had raised TT/APTT at 24 h (P = 0.05). Two deaths were due to continued bleeding despite idarucizumab. Only 17% of patients received prohaemostatic treatments, and none received plasma derivatives. Despite assay availability, dabigatran drug level was only measured in eight patients.ConclusionIdarucizumab helped achieve haemostasis in 15 bleeding patients and allowed 6 patients to undergo urgent surgery. Half the patients had prolonged TT/APTT at 24 h post‐idarucizumab, which was more likely to occur in patients with impaired renal function.
Computed tomography head scans prior to lumbar punctures in suspected meningitis
Authors: Imtiaz Aqilah , Toomath Robyn 
Published: June 2018

AbstractBackgroundThe literature suggests that certain clinical criteria to determine raised intracranial pressure (ICP) should be met if a patient suspected of meningitis is to undergo a computed tomography (CT) head scan prior to having a lumbar puncture (LP).AimTo evaluate whether these criteria were being used by the general medicine department of Auckland City Hospital when requesting CT scans prior to LPs in patients with suspected meningitis.MethodsA total of 37 patients admitted under general medicine with suspected meningitis from 1 January to 31 July 2016 were retrospectively audited based on the clinical evidence justifying the decision to do a CT scan prior to a LP.ResultsOnly 7 of 24 patients who underwent CT scans had met clinical criteria for raised ICP. There were no abnormalities found on any of the CT scans and approximately two‐thirds of these patients had a final diagnosis of viral illness or headache.ConclusionA large number of patients with suspected meningitis under general medicine at Auckland City Hospital are having CT scans without clinical evidence suggestive of raised ICP.
Gaps in the ice: Methamphetamine in Australia; its history, treatment, and ramifications for users and their families
Authors: Gordon Douglas Greg , de Jong Gideon 
Published: June 2018

AbstractIt is now well‐established that Australia has a significant issue with methamphetamine. Recent dramatic changes in manufacturing have led to significant shifts in both the patterns of use and the relative purity of this illicit drug, with the crystalline form of methamphetamine commonly referred to as ‘ice’. Excessive use not only impacts on those taking the drug, but also takes a heavy toll on their families. With few effective treatment options currently available, there is a strong focus on developing replacement pharmacotherapies and examining the efficacy of outpatient counselling and residential treatment options. Recent research in addiction care supports the positive impact that families of users can have on both treatment and recovery for their loved ones. Despite this recognition, there is little current research looking at the experiences of families of users of the uniquely problematic drug methamphetamine. This paper outlines the historical narrative that has led to the current worldwide phenomenon of ice use and explores contemporary directions of research into its impact and potential treatments. In doing so, it outlines the relatively unexplored impact of ice on families and highlights a current need for nursing research into their experiences living with loved ones using the drug.
Barriers to hospital admission among people with eating disorders: A qualitative internet‐based study
Authors: Elran‐Barak Roni , Barak Adi , Cohen‐Ashkenazi Shlomit , Schifter Tamar 
Published: June 2018

AbstractWe seek to describe the barriers that people with eating disorders (EDs) face when undertaking a decision about whether to be admitted for inpatient treatment. Data were retrieved from a moderated ED Internet community website. A descriptive phenomenological approach was used to explore the shared experiences of community members who posted information about their viewpoints on inpatient admission. Three themes emerged: (i) ‘Can I let others help me?’ addressed the question of participants’ ability to cooperate with hospital staff; (ii) ‘Can I give up my daily routine?’ focused on participants’ meaningful lives outside of their ED (school, work, family, friends); and (iii) ‘Can inpatient treatment work?’ revealed a general lack of faith in the ability of inpatient treatment to make a substantial positive contribution. Our findings highlight the difficulties associated with making a decision about inpatient admission and suggest implications for mental‐health professionals.
Self‐management challenges and support needs among kidney transplant recipients: A qualitative study
Authors: Been‐Dahmen Janet M. J. , Grijpma Jan Willem , Ista Erwin , Dwarswaard Jolanda , Maasdam Louise , Weimar Willem , Van Staa AnneLoes , Massey Emma K. 
Published: June 2018

AbstractAimsThis study investigated self‐management challenges and support needs experienced by kidney transplant recipients.BackgroundAfter kidney transplantation, recipients are expected to take an active role in self‐management. However, evidence suggests that nurses experience difficulties operationalizing self‐management support. Greater insight into the recipients’ perspective could help to improve the adequacy and efficacy of nurse‐led self‐management support.DesignA cross‐sectional qualitative study.MethodsFocus groups and individual interviews were carried out with kidney transplant recipients treated in a Dutch university hospital. Directed content analysis (DCA) was used.ResultsForty‐one kidney transplant recipients participated. Challenges after transplantation included becoming an expert patient, adjusting daily life activities, dealing with medical regimen, forming relationships with nurses, dealing with social consequences, dealing with emotions related to transplantation and the donor and improving self‐image. To be able to deal with these challenges, participants wished to receive disease specific knowledge and instruction, share personal experiences with fellow patients, share and discuss not only medical but also emotional and social issues with nurses and wanted to be encouraged through positive feedback. “One‐size fits all” education was considered insufficient in meeting their needs.ConclusionsAfter kidney transplantation, recipients experienced various challenges in dealing with the medical, emotional and social tasks. Current support from nurses overlooked recipients’ emotional and social support needs. Nurses need adequate tools and training to be able to meet recipients’ self‐management support needs.
Mediating effects of workplace violence on the relationships between emotional labour and burnout among clinical nurses
Authors: Kim Hyejin , Kim Ji‐Su , Choe Kwisoon , Kwak Yeunhee , Song Jae‐seok 
Published: June 2018

AbstractAimsTo test a model of the relationship between nurses’ burnout and emotional labour using structural equation modelling to identify the mediating effects of workplace violence.BackgroundNurses are a group that experiences high emotional labour and are exposed to various types of violence in the clinical setting. Burnout is related to emotional labour and exposure of workplace violence, but alternatives to reduce burnout in the context of emotional labour (e.g., reduction in workplace violence) have not been extensively investigated.DesignThis study adopted a cross‐sectional design.MethodsA convenience sample comprising 400 nurses from four university hospitals in Korea was selected from 10 to 30 October 2016. Data on nurses’ level of emotional labour, burnout and workplace violence were collected from participants. A composite‐indicator structural equation model was used to examine the mediation model.ResultsOverall, 356 nurses (89.0%) returned the completed questionnaires. Burnout was significantly and positively associated with emotional labour and workplace violence. In addition, workplace violence mediated the relationship between emotional labour and burnout related to the nursing job.ConclusionThe findings suggest that, to alleviate burnout in clinical nurses due to emotional labour, various programs and policy measures should be adopted to prevent their exposure to workplace violence and to enhance the organizational management of violence.
Re‐conceptualizing pain through patient‐centred care in the complementary and alternative medicine therapeutic relationship
Authors: Agarwal Vinita 
Published: June 2018

AbstractAimsThe study aim was to understand the patient description of the therapeutic relationship with their CAM provider in the context of pain self‐management.BackgroundBecause pain is a subjective state, its assessment depends on patient perception of and response to pain. For nurses to provide empathetic and compassionate care, there is a need to explicate patient perceptions of the therapeutic relationship to (re)conceptualize models of patient‐centred care.DesignInductive qualitative content analysis of patient interviews was conducted to identify how patients described therapeutic relationship themes and understand self‐management of pain.MethodsParticipants were individuals working with a CAM practitioner and solicited through purposive and snowball sampling in collaboration with the practitioners from the mid‐Atlantic region of the United States in 2016 (N = 13). Verbatim transcriptions of audio‐recorded semi‐structured in‐depth interviews (430 single‐spaced pages approximately) were content analysed.FindingsPatients described the therapeutic relationship with the provider as a: (1) giver, who was “in‐tune” with their sense of self to support self‐affirmation through empathetic listening; and (2) guide, who connected the mind and body through their practice to support self‐reflective learning.ConclusionThis description of the CAM therapeutic relationship advances understandings of readjustment of patient relationship with pain through the provider's empathetic listening and connecting the mind and the body to support patient self‐affirmation of pain experiences and self‐reflective learning. The findings illuminate how a feminist standpoint contributes to understandings of the therapeutic relationship that centres patient subjectivity and co‐construction of meaning‐making processes to support self‐management of pain.