bluuebunny/crossref_metadata_2025_split huggingface dataset:
An EpCAM/Trop2 mechanostat differentially regulates collective behaviour of human carcinoma cells
Authors: Aslemarz Azam , Fagotto-Kaufmann Marie , Ruppel Artur , Fagotto-Kaufmann Christine , Balland Martial , Lasko Paul , Fagotto François 
Published: November 2024

AbstractEpCAM and its close relative Trop2 are well-known cell surface markers of carcinoma, but their potential role in cancer metastasis remains unclear. They are known, however, to downregulate myosin-dependent contractility, a key parameter involved in adhesion and migration. We investigate here the morphogenetic impact of the high EpCAM and Trop2 levels typically found in epithelial breast cancer cells, using spheroids of MCF7 cells as an in vitro model. Intriguingly, EpCAM depletion stimulated spheroid cohesive spreading, while Trop2 depletion had the opposite effect. Combining cell biological and biophysical approaches, we demonstrate that while EpCAM and Trop2 both contribute to moderate cell contractility, their depletions differentially impact on the process of “wetting” a substrate, here both matrix and neighboring cells, by affecting the balance of cortical tension at cell and tissue interfaces. These distinct phenotypes can be explained by partial enrichment at specific interfaces. Our data are consistent with the EpCAM-Trop2 pair acting as a mechanostat that tunes adhesive and migratory behaviours.
Artificial intelligence bias in the prediction and detection of cardiovascular disease
Authors: Mihan Ariana , Pandey Ambarish , Van Spall Harriette G. C. 
Published: November 2024

AbstractAI algorithms can identify those at risk of cardiovascular disease (CVD), allowing for early intervention to change the trajectory of disease. However, AI bias can arise from any step in the development, validation, and evaluation of algorithms. Biased algorithms can perform poorly in historically marginalized groups, amplifying healthcare inequities on the basis of age, sex or gender, race or ethnicity, and socioeconomic status. In this perspective, we discuss the sources and consequences of AI bias in CVD prediction or detection. We present an AI health equity framework and review bias mitigation strategies that can be adopted during the AI lifecycle.
High valence MnO2 as an aqueous zinc ion battery cathode prepared using a secondary hydrothermal method
Authors: Lv Xiaoxia , Wang Yun , Zhang Wenjing , Wang Tengfei 
Published: November 2024

A high valence MnO2 (H-MnO2) material was prepared via a simple secondary hydrothermal method and Zn/H-MnO2 aqueous batteries using H-MnO2 as the cathode exhibited excellent capacity and cycling stability.
A solar rotation signature in cosmic dust observed in STEREO spacecraft data
Authors: Chadda Shivank , Malaspina David M. , Baalmann Lennart R. , Sterken Veerle J. , Hunziker Silvan , Sternovsky Zoltan 
Published: November 2024

Aims. Cosmic dust within the Solar System is subject to a range of forces that can modify its trajectory, including gravity, radiation pressure, and the Lorentz force. Lorentz force interactions between the solar wind and dust arise due to the motion of charged dust grains with respect to the solar wind plasma flow and the magnetic fields carried by that flow. For dust grains where the charge to mass ratio is sufficiently large, the Lorentz force can significantly modify the dust grain motion. At the same time, properties of the magnetic fields and plasma in the solar wind are modulated by solar periodicities, such as the 11-year solar cycle and the solar rotation period. These solar periodicities are therefore expected to be imparted onto the trajectories of dust moving within the Solar System via Lorentz force interactions.
Methods. We examined nearly two decades of cosmic dust observations made by the twin STEREO spacecraft at 1 AU for periodicities in the dust flux. We created a two-dimensional toy model to examine whether it is reasonable to expect solar-rotation variability in solar wind magnetic field and plasma velocities to modify the trajectories of dust that reaches 1 AU.
Results. Periodic modulations of the dust flux observed by STEREO at 1 AU are identified near the solar rotation period and its harmonics. The toy model suggests that solar-rotation variability of the solar wind can be sufficient to alter the trajectories of some dust within the Solar System.
Validation to Brazilian Portuguese of the coma recovery scale-revised
Authors: Champs Ana Paula Silva , Santanna Thayse Nayara Freitas do Vale , Couto Christian Marques , Macedo Roberta Correa , Penna Patricia Sola , Cruz Luciana Charchar Vilas Boas , Silva-Neto Rafael Xavier da , Vaz Luiz Sérgio 
Published: November 2024

Abstract
Background To improve the diagnostic accuracy of the state of consciousness of patients with severe brain injury, Giacino et al. introduced the Coma Recovery Scale (CRS) in 1991, which underwent revision in 2004, resulting in the revised CRS scale (CRS-R).
Objective To determine the concurrent validity, as well as inter- and intrarater agreement of the CRS-R's adaptation to Brazilian Portuguese.
Methods This study involved a sample of 30 patients with severe brain injury. Concurrent evaluations were also performed with the Glasgow Coma Scale (GCS) and the Full Outline of UnResponsiveness (FOUR) scale. A total of seven rehabilitation experts were recruited to assess the inter- and intrarater reliability agreement.
Results Interrater reliability was moderate to high for auditory, visual, motor, verbal, communication, and arousal subscales (Cohen weighted kappa = 0.765 to 0.892; p < 0.001). Significant inter and intrarater intraclass correlation coefficients were observed for the total CRS-R scores, all of which were statistically significant (p < 0.001). Also, total CRS-R scores exhibited a high correlation with the total GCS and FOUR scores, indicating acceptable concurrent validity (p < 0.001).
Conclusion The Brazilian Portuguese version of CRS-R can be reliably administered by trained examiners. This study demonstrated substantial to almost perfect interrater agreement for the total score and subscales, as well as high concurrent validity between the Brazilian Portuguese version of CRS-R and the other two standardized behavioral scales.
Community-engaged strategies to improve sexual health services for adults aged 45 and above in the United Kingdom: a qualitative data analysis
Authors: Nunez Michel , Sakuma Yoshiko , Conyers Hayley , Day Suzanne , Terris-Prestholt Fern , Ong Jason J. , Pan Stephen W. , Shakespeare Tom , Tucker Joseph D. , Kpokiri Eneyi E. , Wu Dan 
Published: November 2024

Background Sexual health is an essential component of health and well-being across the life course. However, sexual health research often focuses on young adults and excludes those aged 45 years and older. We organized a national crowdsourcing open call and co-creation events to identify recommendations to improve sexual health service provision for middle-aged and older adults in the United Kingdom (UK). Methods We conducted a crowdsourcing open call and seven co-creation events consisting of workshop-style meetings and one-to-one in-depth interviews. Open call submissions and qualitative data from the co-creation events were analyzed using a thematic approach. A social-ecological framework was used to code deductively, but new codes were allowed to emerge. Thematic categories were organized to describe factors influencing the accessibility and inclusivity of sexual health services for middle-aged and older adults. Results We received 22 submissions in total; of those, 35% of participants reported a disability, 40% of individuals were aged 45–65 years, and 6% of submissions came from individuals that identified as gay/lesbian. Five key themes highlighted that improving sexual health services for adults aged 45 years and over requires a multi-leveled approach: increase sexual health education, enhance patient and provider relationships, utilize community-led sexual health promotion efforts and delivery of reliable sexual health information, improve inclusive sexual health services, and break down sexual health taboos against adults aged 45+ years. Conclusions Our data suggest that middle-aged and older adults can co-create compelling strategies to enhance sexual health services for middle-aged and older adults in the UK. Further implementation research is needed to pilot these strategies.
Multimodal metaphors, political activism and Anglophone nationalism in Cameroon
Authors: Echitchi Raymond 
Published: November 2024

Abstract
This paper is part of a broader study of how separatist leaders from the English-speaking part of Cameroon resort
to discourse in order to push for their main political goal, which is the formation of a separate state. These last few years,
Cameroon politics has been characterized by an increase in secessionist sentiment amongst English-speaking citizens, thus yielding
the so-called Anglophone crisis which has now turned into a full-blown conflict between armed separatists and the country’s
military. The study presented here deals specifically with the use of multimodal metaphors to depict the plight of Anglophone
Cameroonians and also engage them in the struggle for self-determination. Therefore, cartoons published on separatist social media
pages were analyzed following approaches pertaining to cognitive linguistics and social semiotics (Lakoff & Johnson, 1980; Van Leeuwen, 2005). This research
has revealed that the cartoonist(s) resort(s) to various types of metaphor, including the journey metaphor, animal metaphors and
personification.
Two sides of the same coin: the

F

-statistic and the 5-vector method
Authors: D’Onofrio L , Astone P , Dal Pra S , D’Antonio S , Di Giovanni M , De Rosa R , Leaci P , Mastrogiovanni S , Mirasola L , Muciaccia F , Palomba C , Pierini L 
Published: November 2024

Abstract
This work explores the relation between two data-analysis methods used in the search for continuous gravitational waves in LIGO-Virgo-KAGRA data: the

F

-statistic and the 5-vector method. We show that the 5-vector method can be derived from a maximum likelihood framework similar to the

F

-statistic. Our analysis demonstrates that the two methods are statistically equivalent, providing the same detection probability for a given false alarm rate. We extend this comparison to multiple detectors, highlighting differences from the standard approach that simply combines 5-vectors from each detector. In our maximum likelihood approach, each 5-vector is weighted by the observation time and sensitivity of its respective detector, resulting in efficient estimators and analytical distributions for the detection statistic. Additionally, we present the analytical computation of sensitivity for different searches, expressed in terms of the minimum detectable amplitude.
Ternary nodal-line semimetal InNbS2 for highly sensitive broadband terahertz photodetection
Authors: Yang Liu , Wang Dong , Li Jie , Wang Pengdong , Hou Xingang , Tang Keqin , Wang Lin , Dong Zhuo , Zhang Kai 
Published: November 2024

Abstract
Topological nodal-line semimetals (TNLSs) can be understood as a collection of two-dimensional Dirac Fermions along the line, which endows high mobility and extraordinary electrical transport in all directions near the Dirac points. Furthermore, the band geometry at the Fermi level can be easily modified by external field excitations. These features can bring intriguing properties, such as superconducting, Lifshitz transitions, strong light-matter interaction, and high photoconductivity, supporting low-energy carrier excitations and enhanced optical absorption at terahertz (THz) frequency ranges. Herein, a novel TNLS InNbS2-based THz photodetector was fabricated and the photoresponse within 0.02–0.3 THz was explored. A fast response speed of 15.4 μs, a maximum responsivity (R
I) of 1.4 A W–1, and a superb noise equivalent power (NEP) of 11.5 pW Hz−1/2 were achieved at 0.11 THz under a bias voltage of 100 mV due to the high photoconductive gain. Meanwhile, the high-resolution THz transmission imaging of a metallic rainbow was carried out to demonstrate the THz imaging functionality. These results explore new avenues for utilizing TNLSs in THz photodetection and establish a basis for the application in the THz field.
Interface mechanism of photon–magnon–phonon conversion in an epitaxial ferrite–dielectric structure
Authors: Tikhonov V V , Ptashenko A S , Sadovnikov A V 
Published: November 2024

Abstract
It is shown that in the transition layer of an epitaxial yttrium iron garnet (YIG) film, there are effects of intense power conversion and redistribution between electromagnetic waves (EMW), exchange spin waves (ESW) and acoustic waves (AW). These interconversion occurs during the casсade of double hybridization of EMW-ESW and secondary hybridization of ESW-AW. The necessary phase synchronism condition for this is ensured by the smooth distortion of the ESW dispersion within the thickness direction of the transition layer. The secondary hybridization of ESW-AW manifests itself in the intense excitation of AW, which are radiated into the depth of the gadolinium gallium garnet (GGG) substrate. In this case, magnetoacoustic resonances are excited in the YIG-GGG bilayer structure, for the observation of which strict parallelism and optical polishing of the reflecting surfaces of the YIG-GGG structures are required. An important advantage of magnetoacoustic resonances is the record high quality factor in the microwave range and high resistance to external atmospheric influences, which is of significant interest for the fabrication of highly stable magnetoacoustic microwave generators with discrete frequency tuning.
Direct measurements of the conventional and rotational magnetocaloric effects in Gd thick films
Authors: Pereira C S , Almeida R , Niehoff T , Kiefe R , Fontana E , Silva D J , Gottschall T , Wosnitza J , Devillers T , Dempsey N M , Amaral J S , Belo J H 
Published: November 2024

Abstract
Magnetic refrigeration (MR) offers a sustainable and emission-free solution to the prevalent heat-pumping systems used worldwide. Typically, it utilizes the magnetocaloric effect (MCE) to achieve cooling by changing the external magnetic field intensity. However, an alternative approach involves maintaining a fixed field intensity while manipulating its orientation to induce temperature changes, in an effect known as the rotating MCE (RMCE). While the RMCE has been extensively studied in materials with magnetocrystalline anisotropy, its investigation in polycrystalline magnetocaloric samples with asymmetric shapes has been lacking until recently. In this case, the RMCE is induced by the demagnetizing effect, which becomes more pronounced in high aspect-ratio sample geometries exhibiting different effective demagnetizing factors at different orientations, such as in films. In this work, we characterize the conventional and rotational MCE of 40 μm-thick gadolinium films through magnetization and direct temperature measurements. The maximum adiabatic temperature change achieved under a 1 T magnetic field was 2.05 K when the film was oriented in plane with the field and 1.25 K when the film was perpendicular to the magnetic field, corresponding to an adiabatic temperature difference of around 0.8 K which may be induced through magnetic field rotation. Additionally, the maximum adiabatic temperature change upon rotation is shown to exhibit a non-monotonous behavior with field intensity, displaying a peak value for field intensities of around 0.8 T. The high aspect ratio of the Gd film has been demonstrated to considerably enhance the intensity of demagnetizing field-based RMCE compared to bulk samples, paving the way for future research in this emerging field of MR cooling.
Doses from ionising radiation in paediatric cardiac catheterisations in Norway 1975–2021
Authors: Afroz S , Østerås B H , U S Thevethas , Meo M , Jahnen A , Dabin J , Thierry-Chef I , Robsahm T E , Døhlen G , Olerud H M 
Published: November 2024

Abstract
Paediatric patients with congenital heart disease often undergo cardiac catheterisation procedures and are exposed to considerable ionising radiation early in life. This study aimed to develop a method for estimating the dose area product (P
KA) from paediatric cardiac catheterisation procedures (1975–1989) at a national centre for paediatric cardiology and to evaluate trends in P
KA and exposure parameters until 2021. Data from 2200 catheterisation procedures on 1685 patients (1975–1989) and 4184 procedures on 2139 patients (2000–2021) under 18 years of age were retrospectively collected. P
KA values were missing for 1975–1989 but available from 2000 onward. The missing P
KA was estimated from air kerma and beam area, based on exposure records and input from clinicians working at that time. P
KA trends were analysed over time and age. There was a 71% reduction in median P
KA from the period 1975–1989 (median 6.63 Gy cm2) to 2011–2021 (1.91 Gy cm2). The P
KA increases significantly (p = 0.0001) with patient age, which was associated with body weight. Approximately 80% of the total P
KA was from cine acquisition in 1975–1989, while 20% was from fluoroscopy. The P
KA estimate during 1975–1989 was considerably impacted by the assumptions of missing parameters such as tube filtration, focus-to-heart distance, beam area, and number of cine series. The decreasing trend in P
KA values was attributed to advancements in both technologies and clinical practices. The high contribution of cine acquisition to the total dose during 1975–1989 was due to factors such as a high frame rate, multiple acquisitions, and high tube current. The estimated P
KA values for the period 1975–1989 are of importance for the dose reconstruction and risk assessments in the EU epidemiology project Health Effects of Cardiac Fluoroscopy and Modern Radiotherapy in Pediatrics(HARMONIC).
Design of a self-referenced laser scanning and ranging system
Authors: Yang Qingzhao , Shi Liheng , Zhou Siyu , Zhang Ruixue , Yuan Ding , Xiao Lin , Yang Hongzhi , Xie Yang , Li Lin , Wu Guanhao 
Published: November 2024

Abstract
The laser scanning and ranging system (LSRS) is a pivotal technology for conducting high-precision multi-dimensional measurements, with diverse applications in remote sensing, satellite formation flying, and surface profilometry. However, the capability to achieve accurate measurement of the current system is limited by the beam-pointing mechanism. Specifically, the rotation angle of the beam-pointing mechanism is too small to achieve zero-position self-calibration, and this mechanism can introduce errors that exceed the precision of distance measurement. Herein, we propose a self-referenced LSRS that can directly determine the measurement origin and avoid motion-induced optical path length errors into the interferometric arms. This system is achieved by placing the reference arm of the measurement system after the beam-pointing mechanism in the optical path. Using a dual-comb ranging system with a precision of ∼0.8 μm, we validated the performance of our design through scanning experiments with hollow retroreflectors and surface profile reconstruction of a gauge-block assembly. The experimental results demonstrate that our design achieves accurate measurements without pre-calibration or post-compensation, thereby enhancing its applicability to next-generation space missions.
A feature-preserving simplification method for dense point clouds based on voxel priority filtering
Authors: Zhou Zhihao , Zhu Huabo , Chen Yuzhao , Han Xu , Tao Yourui 
Published: November 2024

Abstract
The inherently high-dimensional and information-dense nature of point clouds requires substantial storage and computing resources, which severely limits their widespread applicability. It is crucial to simplify the point cloud data efficiently and accurately for various downstream tasks. To address the challenges of detail loss and time consumption, we propose a novel method that utilizes voxel filtering and partition sampling strategy for point cloud simplification. The voxel grid structure of original point cloud is established based on the spatial location of the points. The voxels are then classified as feature and non-feature voxels by calculating the Eigenentropy on the Gaussian sphere. Combined with an effective partition strategy for further sampling, the proposed method ensures global geometric consistency and preserves distinct features in the simplified point cloud. To evaluate the performance comprehensively, we conducted extensive experiments on the models of standard, industrial real-world scanning and natural scene datasets. Compared with several relevant approaches, the results demonstrate that the proposed method significantly enhances the flexibility and accuracy of point cloud simplification. It exhibits superior capabilities in engineering applications such as visualization, 3D reconstruction, and point cloud registration.
A method to get perfect balance point of differential eddy current displacement sensors
Authors: Zhu Shuyu , Chen Guangzheng , Xu Tao , Yin Jing , Feng Zhihua 
Published: November 2024

Abstract
This study introduces a novel method to increase the stability of the balance point in precision differential eddy current sensor (ECS) displacement sensors, which is crucial for achieving optimal performance and improving the interchangeability of sensor probes. The temperature drift coefficient at the electrical balance point (BTC), a common issue affecting the accuracy and reliability of measurements, is addressed through our approach. The BTC can be accurately adjusted by fine-tuning the length of the aluminum target, which aligns the zero-temperature drift position with the electrical balance position, thereby achieving a perfect balance point. The experimental results demonstrate that the proposed method significantly reduces the temperature drift near the balance point of the differential ECS. The BTC was effectively reduced from −7.21 nm/°C to 0.22 nm/°C. This substantial reduction in the BTC enhances the stability of the sensor, facilitating more reliable measurements in high-precision applications.
Removal of crossbar-switch interference from multi-rate beam position signals with wavelet packet transform
Authors: Tang Leilei , Sun Baogen , Wu Ruizhe , Lu Ping , Ma Xiaochao , Wang Anxin 
Published: November 2024

Abstract
Electron beam position measurement of storage rings is a typical multi-channel signal acquisition system that suffers from crossbar-switch (CS) interference consisting of massive harmonics and artifacts when CS-based channel disequilibrium compensation is used. However, it is not an effective method for removing the interference from the turn-by-turn (TBT) beam position signal in CS working. In this paper, a method that combines wavelet packet transform and coefficient baseline shift techniques is proposed to remove the CS interference without distorting the actual TBT signal. This method starts with wavelet packet decomposition of the contaminated TBT signal, then wavelet coefficients are further processed by the baseline shift and finally the processed coefficients of whole subbands are reconstructed through filter banks to obtain a clean TBT signal. As a result, a clean and undistorted fast acquisition signal is obtained at a relatively slow rate through partial reconstruction without using a decimation filter and a notch filter. Results with synthetic and real TBT signals demonstrate the effectiveness of the proposed method. Moreover, the relative root mean square error and normalized correlation coefficient criteria are measured, which also show that the proposed method does not distort the actual TBT signal while removing the CS interference.