bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between the estrogen receptor α gene polymorphisms rs2234693 and rs9340799 and severe and mild pre-eclampsia: a meta-analysis
Authors: Zhao Ge , Cai Yunfei , Liu Jing , Meng Tao 
Published: January 2019

Abstract
This meta-analysis was performed in order to determine the associations between the estrogen receptor α (ESR1) gene PvuII site (-397T/C, rs2234693) and XbaI site (-351A/G, rs9340799) polymorphisms with severe and mild pre-eclampsia. Eligible studies were identified by searching PubMed, Medline, Embase, China National Knowledge Infrastructure (CNKI), and WanFang databases until May 2018. The pooled odds ratio (OR) and 95% confidence interval (CI) were used to calculate the associations. Six articles (consisting of seven studies; one article was considered as two separate studies with two different subpopulations) investigated the ESR1 gene PvuII -397T/C and XbaI -351A/G polymorphisms in severe and mild pre-eclampsia patients and included controls. The pooled results indicated an increased risk of severe pre-eclampsia for the XbaI -351A/G polymorphism (OR = 1.67, 95% CI = 1.10–2.25, P=0.017 for GG compared with AA+GA; OR = 1.81, 95% CI = 1.17–2.82, P=0.008 for GG compared with GA). The GG genotype of the ESR1 XbaI polymorphism could be a genetic risk factor for severe pre-eclampsia susceptibility. However, the ESR1 gene PvuII -397T/C polymorphism was not significantly associated with the risk of severe pre-eclampsia, and there was no association between mild pre-eclampsia and the ESR1 gene PvuII -397T/C and XbaI -351A/G polymorphisms separately. The current meta-analysis indicates that the ESR1 XbaI genetic polymorphism may be associated with severe pre-eclampsia. However, there was no association of the ESR1 gene PvuII and XbaI polymorphisms with the risk of mild pre-eclampsia. Owing to the low statistical power, the results may not be sufficiently robust and this conclusion should be interpreted cautiously, which highlights the requirement for large-scale and high-quality studies in this field.
Discovery and follow-up of the unusual nuclear transient OGLE17aaj
Authors: Gromadzki M. , Hamanowicz A. , Wyrzykowski L. , Sokolovsky K. V. , Fraser M. , Kozłowski Sz. , Guillochon J. , Arcavi I. , Trakhtenbrot B. , Jonker P. G. , Mattila S. , Udalski A. , Szymański M. K. , Soszyński I. , Poleski R. , Pietrukowicz P. , Skowron J. , Mróz P. , Ulaczyk K. , Pawlak M. , Rybicki K. A. , Sollerman J. , Taddia F. , Kostrzewa-Rutkowska Z. , Onori F. , Young D. R. , Maguire K. , Smartt S. J. , Inserra C. , Gal-Yam A. , Rau A. , Chen T.-W. , Angus C. R. , Buckley D. A. H. 
Published: January 2019

Aims. We report on the discovery and follow-up of a peculiar transient, OGLE17aaj, which occurred in the nucleus of a weakly active galaxy. We investigate whether it can be interpreted as a new candidate for a tidal disruption event (TDE).
Methods. We present the OGLE-IV light curve that covers the slow 60-day-long rise to maximum along with photometric, spectroscopic, and X-ray follow-up during the first year.
Results. OGLE17aaj is a nuclear transient exhibiting some properties similar to previously found TDEs, including a long rise time, lack of colour-temperature evolution, and high black-body temperature. On the other hand, its narrow emission lines and slow post-peak evolution are different from previously observed TDEs. Its spectrum and light-curve evolution is similar to F01004-2237 and AT 2017bgt. Signatures of historical low-level nuclear variability suggest that OGLE17aaj may instead be related to a new type of accretion event in active super-massive black holes.
Multi-phase outflows in Mkn 848 observed with SDSS-MaNGA integral field spectroscopy
Authors: Perna M. , Cresci G. , Brusa M. , Lanzuisi G. , Concas A. , Mainieri V. , Mannucci F. , Marconi A. 
Published: January 2019

Aims. The characterisation of galaxy-scale outflows in terms of their multi-phase and multi-scale nature, amount, and effects of flowing material is crucial to place constraints on models of galaxy formation and evolution. This study can proceed only with the detailed investigation of individual targets.
Methods. We present a spatially resolved spectroscopic optical data analysis of Mkn 848, a complex system consisting of two merging galaxies at z ∼ 0.04 that are separated by a projected distance of 7.5 kpc. Motivated by the presence of a multi-phase outflow in the north-west system revealed by the SDSS integrated spectrum, we analysed the publicly available MaNGA data, which cover almost the entire merging system, to study the kinematic and physical properties of cool and warm gas in detail.
Results. Galaxy-wide outflowing gas in multiple phases is revealed for the first time in the two merging galaxies. We also detect spatially resolved resonant Na ID emission associated with the outflows. The derived outflow energetics (mass rate, and kinetic and momentum power) may be consistent with a scenario in which both winds are accelerated by stellar processes and AGN activity, although we favour an AGN origin given the high outflow velocities and the ionisation conditions observed in the outflow regions. Further deeper multi-wavelength observations are required, however, to better constrain the nature of these multi-phase outflows. Outflow energetics in the North-West system are strongly different between the ionised and atomic gas components, the latter of which is associated with mass outflow rate and kinetic and momentum powers that are one or two dex higher; those associated with the south-east galaxy are instead similar.
Conclusions. Strong kiloparsec-scale outflows are revealed in an ongoing merger system, suggesting that feedback can potentially impact the host galaxy even in the early merger phases. The characterisation of the neutral and ionised gas phases has proved to be crucial for a comprehensive study of the outflow phenomena.
Supervised neural networks for helioseismic ring-diagram inversions
Authors: Alshehhi Rasha , Hanson Chris S. , Gizon Laurent , Hanasoge Shravan 
Published: January 2019

Context. The inversion of ring fit parameters to obtain subsurface flow maps in ring-diagram analysis for eight years of SDO observations is computationally expensive, requiring ∼3200 CPU hours.
Aims. In this paper we apply machine-learning techniques to the inversion step of the ring diagram pipeline in order to speed up the calculations. Specifically, we train a predictor for subsurface flows using the mode fit parameters and the previous inversion results to replace future inversion requirements.
Methods. We utilize artificial neural networks (ANNs) as a supervised learning method for predicting the flows in 15° ring tiles. We discuss each step of the proposed method to determine the optimal approach. In order to demonstrate that the machine-learning results still contain the subtle signatures key to local helioseismic studies, we use the machine-learning results to study the recently discovered solar equatorial Rossby waves.
Results. The ANN is computationally efficient, able to make future flow predictions of an entire Carrington rotation in a matter of seconds, which is much faster than the current ∼31 CPU hours. Initial training of the networks requires ∼3 CPU hours. The trained ANN can achieve a rms error equal to approximately half that reported for the velocity inversions, demonstrating the accuracy of the machine learning (and perhaps the overestimation of the original errors from the ring-diagram pipeline). We find the signature of equatorial Rossby waves in the machine-learning flows covering six years of data, demonstrating that small-amplitude signals are maintained. The recovery of Rossby waves in the machine-learning flow maps can be achieved with only one Carrington rotation (27.275 days) of training data.
Conclusions. We show that machine learning can be applied to and perform more efficiently than the current ring-diagram inversion. The computation burden of the machine learning includes 3 CPU hours for initial training, then around 10−4 CPU hours for future predictions.
(Im)politeness, morality and the internet
Authors: Xie Chaoqun 
Published: January 2019

AbstractMuch recent research has contributed to the emergence of a moral turn in (im)politeness research, further confirming the evaluative nature of (im)politeness and the moral basis of (im)politeness evaluations, and further illuminating, among other things, what is really at work when (im)politeness evaluations take place, what the moral order consists of and how the moral order influences (im)politeness evaluations. Meanwhile, thanks to much emphasis on the instrumentality of words and utterances, a distinction can be discerned between ‘politeness without’ (or practical politeness) and ‘politeness within’ (or true politeness). Politeness within is true and truthful, but politeness without is not necessarily so. True politeness may be in when self is out. This special issue aims to further foreground the link between (im)politeness and morality in people’s online interactions, revealing something about ourselves and about our life-worlds.
The personal and/as the political
Authors: Georgakopoulou Alex , Vasilaki Maria 
Published: January 2019

AbstractDrawing on our previous work on the role of small stories in social-mediatized engagements with the Greek socio-economic crisis (Georgakopoulou 2014,2015), in this article, we set out to shed light on impoliteness on social media through the lens of small stories research. We explore how Facebook and YouTube commenters “bash” political leaders and perceived political opponents and attribute blame to them for the crisis, through comments that attest to specific links of doing impoliteness with storying the crisis. Bashing has been previously related to the affective reactions of participants in online comments on current affairs. In this case, we bring to the fore a salient combination in our data of (mainly on-record) impoliteness strategies for bashing politicians with specific narrating positions in stories about the crisis: the narrator as sufferer, as witness of suffering, and as spokesperson for collective suffering. We argue that in all these cases, on-record impoliteness is normally placed at the end of a small story and presented as legitimated and justified by the preceding account. We conclude with the implications of the association of impoliteness targeting public figures with social-mediatized processes of personalizing and constructing expertise on the basis of experience on the one hand and, on the other hand, of jointly (re)asserting moral order in political affairs.
“Ya bloody drongo!!!”
Authors: Sinkeviciute Valeria 
Published: January 2019

AbstractThis paper explores impoliteness-related discourse on Facebook as a form of expressing situated moral judgement. The analysis focuses on negative and aggressive comments as a response to one public post that claims the non-existence of Australia. The content of the post indicates the threat to national identity of anyone who associates themselves with the country. As a result, a large number of impolite comments were made. A qualitative analysis of the dataset (limited to one month from the post’s publication) reveals four main strategies that are used in order to express the judgement of the post’s inappropriateness and repair the wrongdoing. Those range from insults of the author’s mental abilities and suspicion of drug use to violence-related discourse (e.g., death threats) and counter-attack of the author’s national identity. This paper, thus, aims to contribute to a growing area of research into online impoliteness.
Impoliteness online
Authors: Kienpointner Manfred 
Published: January 2019

AbstractThis paper provides an overview of the strategies and techniques of hate speech in online discourse (on online discourse or computer-mediated communication in general cf. e.g.,Schwarzhaupt-Scholz 2004;Schmidt 2013;Dittler and Hoyer 2014; Seargeant and Tagg 2014). Based on a collection of online texts belonging to different genres (discussion forums, blogs, social media, tweets, homepages), this paper will provide a qualitative analysis of destructively impolite utterances in online interactions. This analysis will make use of the standard typologies of impoliteness and their recent extensions (such asCulpeper 1996,2005,2011;Kienpointner 1997,2008;Kleinke and Bös 2015), but some modifications and elaborations of these typologies will also be taken into account. Moreover, social, cultural and political reasons for the recent dramatic increase in hate speech in online interactions will be explored. Finally, the problem of how to deal with this destructive use of language will be briefly discussed and some possible solutions will be suggested (cf.Banks 2010).
Translanguaging in culturally sustaining systemic functional linguistics
Authors: Khote Nihal , Tian Zhongfeng 
Published: January 2019

AbstractIn today’s globalized multilingual classrooms, deficit ideologies tend to disregard the cultural capital and mobile semiotic resources that immigrant and culturally diverse students bring with them (Blommaert 2010). There is a growing need to focus on culturally sustaining pedagogies that reframe how we think about teaching multilingual learners (Paris and Alim 2017). By bringing two perspectives – Halliday’s systemic functional linguistics (SFL) (Halliday 1993) theory andGarcía’s (2009)notion of translanguaging – into dialogue, we explore their conceptual alignments and complementarities. Building upon this, we envision culturally sustaining SFL as an integrative framework which holds the promise of fostering meaningful heteroglossic contexts of learning for multilingual learners in supporting their multiliteracies (seeKhote 2017;Harman and Khote 2018). Data from one of the author’s English Language Arts (ELA) classroom will further illustrate: (a) how students’ complex linguistic repertoires were mobilized as a foundational resource for developing disciplinary literacy, and (b) how multilingual students engaged with the curriculum to interrogate discourses that diminish their authentic participation in the classroom.
Convergences and alignments between translanguaging and critical literacies work in bilingual
classrooms
Authors: Lau Sunny Man Chu 
Published: January 2019

Abstract
Translanguaging pedagogy, stemming from a dynamic view of bilingualism, aims to creatively mobilize students’
plural communicative repertoires for meaningful learning and destabilize hegemonic discourses about minoritized students and
languages. It espouses in itself a criticality that raises awareness of the inequitable and arbitrary nature of language
hierarchy, separation and marginalization for social justice purposes, a central tenet shared with critical literacy (CL)
education. This paper explores the convergences and alignments between translanguaging pedagogy and CL and the affordances for
critical bilingual learning when employed together. To examine the synergies between translanguaging and CL, I use Janks’ (2010) synthesis CL model to tease out their interconnections as well as their
transformative potential when used jointly in bilingual classrooms. Elaborating on key literacy events from a CL project with
emergent bilingual students, this paper illustrates how translanguaging opens up spaces for rigorous language and CL
engagement.
What Is the Relationship between Worker Skills and Outcomes for Families in Child and Family Social Work?
Authors: Forrester Donald , Westlake David , Killian Mike , Antonopolou Vivi , McCann Michelle , Thurnham Angela , Thomas Roma , Waits Charlotte , Whittaker Charlotte , Hutchison Douglas 
Published: January 2019

AbstractCommunication skills are fundamental to social work, yet few studies have directly evaluated their impact. In this study, we explore the relationship between skills and outcomes in 127 families. An observation of practice was undertaken on the second or third meeting with a family. Practice quality was evaluated in relation to seven skills, which were grouped into three dimensions: relationship building, good authority and evocation of intrinsic motivation. Outcomes at approximately six months were parent-reported engagement (Working Alliance Inventory), Goal Attainment Scaling (GAS), an eleven-point family life satisfaction rating, the Family Environment Scale and General Health Questionnaire and service outcomes from agency records including children entering care. Relationship-building skills predicted parent-reported engagement, although good authority and evocation had stronger relationships with outcome measures. Where workers visited families more often, relationships between skills and outcomes were stronger, in part because workers had more involvement and in part because these families were more likely to have significant problems. The relationship between skills and outcomes was complicated, although the findings provide encouraging evidence that key social work skills have an influence on outcomes for families.
Diminished Locomotor Control Is Associated With Reduced Neurovascular Coupling in Older Adults
Authors: Jor’dan Azizah J , Manor Brad , Iloputaife Ikechukwu , Habtemariam Daniel A , Bean Jonathan F , Sorond Farzaneh A , Lipsitz Lewis A 
Published: January 2019

Abstract

Background
Walking, especially while dual-tasking, requires functional activation of cognitive brain regions and their connected neural networks. This study examined the relationship between neurovascular coupling (NVC), as measured by the change in cerebral blood flow in response to performing a cognitive executive task, and dual-task walking performance.

Methods
Seventy community-dwelling older adults aged 84 ± 5 years within the Maintenance of Balance, Independent Living, Intellect and Zest in the Elderly (MOBILIZE) Boston Study were divided into LOW (n = 35) and HIGH (n = 35) NVC. NVC was quantified by transcranial Doppler ultrasound and stratified by the median change in cerebral blood flow velocity of the middle cerebral artery induced by the performance of the n-back task of executive function. Walking metrics included walking speed, step width, stride length, stride time, stride time variability, and double-support time from single- and dual-task walking conditions, as well as the “cost” of dual-tasking.

Results
During both single- and dual-task walking, older adults with LOW NVC displayed narrower step width (p = .02 and p = .02), shorter stride length (p = .01 and p = .02), and longer double-support time (p = .03 and p = .002) when compared with the HIGH group. During single-task walking only, LOW NVC was also linked to slower walking speed (p = .02). These associations were independent of age, height, hypertension, atrial fibrillation, and assistive device. The LOW and HIGH NVC groups did not differ in dual-task costs to walking performance.

Conclusion
In older adults, diminished capacity to regulate cerebral blood flow in response to an executive function task is linked to worse walking performance under both single- and dual-task conditions, but not necessarily dual-task costs.
Executive Function and Subjective Well-being in Middle and Late Adulthood
Authors: Toh Wei Xing , Yang Hwajin , Hartanto Andree 
Published: January 2019

Abstract

Objectives
A growing body of research has investigated psychosocial predictors of subjective well-being (SWB), a key component of healthy aging, which comprises life satisfaction and affective well-being. However, few studies have examined how executive function (EF)—a collection of adaptive, goal-directed control processes—could affect SWB in middle and late adulthood.

Methods
By analyzing a nationally representative adult cohort ranging from the early 30s to early 80s from the Midlife Development in the United States 2 study, we examined two potential mediators (i.e., sense of control vs positive reappraisal) that could underlie the relation between EF and SWB. Further, we assessed how these mediational pathways would differ across midlife and older adulthood.

Results
Our results revealed that sense of control, but not positive reappraisal, significantly mediated the relation between EF and life satisfaction and affective well-being. Moreover, these mediation effects were significantly moderated by age, with more pronounced effects among older adults.

Discussion
We found that EF in later adulthood facilitates a sense of control over obstacles that interfere with the attainment of goals, which in turn is associated with greater life satisfaction and positive affect. This underscores the role of EF as an increasingly valuable resource that buffers against declines in sense of control and SWB in late adulthood.
Asymptotic analysis of drug dissolution in two layers having widely differing diffusivities
Authors: Vynnycky Michael , McKee Sean , Meere Martin , McCormick Christopher , McGinty Sean 
Published: January 2019

Abstract
This paper is concerned with a diffusion-controlled moving boundary problem in drug dissolution, in which the moving front passes from one medium to another for which the diffusivity is many orders of magnitude smaller. The classical Neumann similarity solution holds while the front is passing through the first layer, but this breaks down in the second layer. Asymptotic methods are used to understand what is happening in the second layer. Although this necessitates numerical computation, one interesting outcome is that only one calculation is required, no matter what the diffusivity is for the second layer.
Pro: Vascular access surveillance in mature fistulas: is it worthwhile?
Authors: Tessitore Nicola , Poli Albino 
Published: January 2019

Abstract
Guidelines recommend regular screening of mature arteriovenous fistulas (AVFs) for preemptive repair of significant stenosis (≥50% lumen reduction) at high risk of thrombosis, identifiable from clinical signs of access dysfunction (monitoring) or by measuring access blood flow (Qa surveillance), which also enables stenosis detection in functional accesses. To compare the value of Qa surveillance versus monitoring, a meta-analysis was performed on the randomized controlled trials (RCTs) comparing the two screening strategies. It emerged that correcting stenosis identified by Qa surveillance significantly halved the risk of thrombosis [relative risk (RR) = 0.51, 95% confidence interval (CI) 0.35–0.73] and access loss (RR = 0.47, 95% CI 0.28–0.80) in comparison with intervention prompted by clinical signs of access dysfunction. One small RCT aiming to identify an optimal Qa threshold showed that stenosis repair at Qa >500 mL/min produced a significant 3-fold reduction in the risk of thrombosis (RR = 0.37, 95% CI 0.12–0.97) and access loss (RR = 0.36, 95% CI 0.09–0.99) in comparison with intervening when Qa dropped to <400 mL/min as per guidelines. To test the real-world benefits of Qa surveillance, the expected RCT-based thrombosis and access loss rates with Qa surveillance were compared with the rates with monitoring reported in observational studies: the expected thrombosis and access loss rates with surveillance were only lower than with monitoring when a Qa >500 mL/min was considered (2.4, 95% CI 1.0–4.6 and 2.2, 95% CI 0.7–5.0 versus 9.4, 95% CI 7.4–11.3 and 10.3, 95% CI 7.7–13.4 events per 100 AVFs-year, P ≤ 0.024), suggesting that in clinical practice adopting Qa surveillance may only be worthwhile at centres with high thrombosis and access loss rates associated with monitoring, and adopting Qa thresholds >500 mL/min for elective stenosis repair.