bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pathophysiologic mechanisms, neuroimaging and treatment in wake-up stroke
Authors: Elfil Mohamed , Eldokmak Mohamed , Baratloo Alireza , Ahmed Nada , Amin Hardik P. , Koo Brian B. 
Published: September 2019

AbstractWake-up stroke (WUS) or ischemic stroke occurring during sleep accounts for 14%–29.6% of all ischemic strokes. Management of WUS is complicated by its narrow therapeutic time window and attributable risk factors, which can affect the safety and efficacy of administering intravenous (IV) tissue plasminogen activator (t-PA). This manuscript will review risk factors of WUS, with a focus on obstructive sleep apnea, potential mechanisms of WUS, and evaluate studies assessing safety and efficacy of IV t-PA treatment in WUS patients guided by neuroimaging to estimate time of symptom onset. The authors used PubMed (1966 to March 2018) to search for the term “Wake-Up Stroke” cross-referenced with “pathophysiology,” ‘‘pathogenesis,” “pathology,” “magnetic resonance imaging,” “obstructive sleep apnea,” or “treatment.” English language Papers were reviewed. Also reviewed were pertinent papers from the reference list of the above-matched manuscripts. Studies that focused only on acute Strokes with known-onset of symptoms were not reviewed. Literature showed several potential risk factors associated with increased risk of WUS. Although the onset of WUS is unknown, a few studies investigated the potential benefit of magnetic resonance imaging (MRI) in estimating the age of onset which encouraged conducting clinical trials assessing the efficacy of MRI-guided thrombolytic therapy in WUS.
THE AUTHORITY OF MORAL OVERSIGHT: ON THE LEGITIMACY OF CRIMINAL LAW
Authors: Bennett Christopher 
Published: September 2019

ABSTRACTAn influential view in recent philosophy of punishment is that the apparatus of criminal justice should be geared at least in part to state censure of wrongdoing. I argue that if it were to be so geared, such an apparatus would make ambitious claims to authority, and that the legitimacy of the relevant state would then depend on whether those claims can be vindicated. This paper looks first at what kind of authority is being claimed by this apparatus. The criminal law, I argue, cannot merely be thought of as claiming a right to rule and to be obeyed. Rather, its authority is better understood as the authority of moral oversight: a power to alter, at will (though within certain limits), citizens’ liability to answer for their compliance with—and to be officially censured for their failure to comply with—a designated set of pre-existing moral 7reasons. The paper then looks at whether a state could realistically be expected to possess such authority—that is, whether a state that claims to have such a power could ever be legitimate.
Assessing the impact of food insecurity on HIV medication adherence in the context of an integrated care programme for people living with HIV in Vancouver, Canada
Authors: Koehn Katrina , McLinden Taylor , Collins Alexandra B , McDougall Patrick , Baltzer-Turje Rosalind , Miewald Christiana , Wang Lu , Li Jenny , Salters Kate A , Hogg Robert S , Parashar Surita 
Published: September 2019

AbstractObjective:Food insecurity, or self-reports of inadequate food access due to limited financial resources, remains prevalent among people living with HIV (PLHIV). We examined the impact of food insecurity on combination antiretroviral therapy (cART) adherence within an integrated care programme that provides services to PLHIV, including two meals per day.Design:Adjusted OR (aOR) were estimated by generalized estimating equations, quantifying the relationship between food insecurity (exposure) and cART adherence (outcome) with multivariable logistic regression.Setting:We drew on survey data collected between February 2014 and March 2016 from the Dr. Peter Centre Study based in Vancouver, Canada.Participants:The study included 116 PLHIV at baseline, with ninety-nine participants completing a 12-month follow-up interview. The median (quartile 1–quartile 3) age was 46 (39–52) years at baseline and 87 % (n 101) were biologically male at birth.Results:At baseline, 74 % (n 86) of participants were food insecure (≥2 affirmative responses on Health Canada’s Household Food Security Survey Module) and 67 % (n 78) were adherent to cART ≥95 % of the time. In the adjusted regression analysis, food insecurity was associated with suboptimal cART adherence (aOR = 0·47, 95 % CI 0·24, 0·93).Conclusions:While food provision may reduce some health-related harms, there remains a relationship between this prevalent experience and suboptimal cART adherence in this integrated care programme. Future studies that elucidate strategies to mitigate food insecurity and its effects on cART adherence among PLHIV in this setting and in other similar environments are necessary.
Assessing the economic viability of integrated crop−livestock systems in Mato Grosso, Brazil
Authors: dos Reis Júlio César , Kamoi Mariana Y. T. , Latorraca Daniel , Chen Rafael F. F. , Michetti Miqueias , Wruck Flávio Jesus , Garrett Rachael D. , Valentim Judson Ferreira , Rodrigues Renato de Aragão Ribeiro , Rodrigues-Filho Saulo 
Published: September 2019

AbstractPopulation growth and rising incomes have led to increasing global demand for meat products. Meeting this demand without converting remaining natural ecosystems or further degrading ecosystems is one of the largest global sustainability challenges. A critical step to overcoming this challenge is to increase the productivity of livestock grazing systems, which occupy the largest land area of any type of agriculture globally. Integrated crop−livestock systems (iCL), which re-couple crop and livestock production at the farm scale, have been considered a promising strategy to tackle this challenge by restoring degraded pasturelands and providing supplemental nutrition to livestock. However, few studies have analyzed the economic viability of such systems, especially in Brazil, an important player in global food systems. This paper presents an economic analysis of iCL in Mato Grosso, Brazil, the largest grain and beef producer in the country, which spans the ecologically diverse Amazon, Cerrado and Pantanal biomes. We compare the economic performance of an integrated soybean/corn and beef cattle system to a continuous crop (soybean/corn) system and a continuous livestock (beef cattle) production system from 2005 to 2012. We use empirical case study data to characterize a ‘typical’ farm for each production system within the study region. We find that the integrated crop−livestock system has a higher annual net present value (NPV) per hectare (ha) than continuous cropping or livestock under a range of discount rates. However, under a scenario of substantially higher crop prices, the continuous cropping outperforms iCL. While iCL is not feasible in all regions of the Amazon and Cerrado, our results indicate that in places where the biophysical and market conditions are suitable for production, it could be a highly profitable way to intensify cattle production and potentially spare land for other uses, including conservation. Nevertheless, additional credit and technical support may be needed to overcome high upfront costs and informational barriers to increase iCL areas as a sustainable development strategy for agriculture in the Amazon and Cerrado regions.
Introduction to the Kornai 90 Symposium
Authors: Piroska Dóra , Rosta Miklós 
Published: September 2019

AbstractThis introduction to the Kornai 90 Symposium briefly overviews János Kornai's rich scholarship with the aim of highlighting those features of Kornai's work that are of particular interest to institutional economists. Above all, the introduction browses through some of his main works, such asOvercentralization,Anti-Equilibrium, andEconomics of Shortage, with a special emphasis on the soft budget constraint,The Socialist System, and Kornai's latest writings on Hungary's U-turn. We invoke the political contexts of these works to suggest their impact on Kornai's diverse questions, changing methods, and the constraint they put on his conclusions as well as on the reception of the research results. In the end, we underline that Kornai was an independent scholar with an interest in a variety of methods and approaches, who nevertheless, or maybe consequently, had a remarkable impact on the thinking of social scientists and practitioners alike. The four papers presented in the symposium are testimonies to the living impact of Kornai'soeuvreon institutionalist analysis today.
Meta-waveguide analysis and implementation for using as a slot array antenna
Authors: Fallah Mahmoud , Khalaj-Amirhosseini Mohammad 
Published: September 2019

AbstractThis paper presents a novel concept named meta-waveguide structures to design slot array antennas based on metasurface. The proposed method investigates the geometrical parameters of the embedded metasurface and their relations to build up the engineered electric and magnetic fields to introduce efficient slot array antennas. This approach eliminates the necessity of using the well-known offsets in typical slot arrays, which can be benefited from linear array theorem. This idea is realized by employing successive filed curvature along the propagation direction, utilizing periodic metasurfaces. Thereafter, a step-by-step algorithm is recommended to design an efficient slot array antenna. Finally, a prototype is fabricated and tested experimentally validating the theoretical calculations.
The Nordic Twin Study on Cancer — NorTwinCan
Authors: Harris Jennifer R. , Hjelmborg Jacob , Adami Hans-Olov , Czene Kamila , Mucci Lorelei , Kaprio Jaakko ,   Nordic Twin Study of Cancer (NorTwinCan) Collaboration
Published: September 2019

AbstractNordic twin studies have played a critical role in understanding cancer etiology and elucidating the nature of familial effects on site-specific cancers. The NorTwinCan consortium is a collaborative effort that capitalizes on unique research advantages made possible through the Nordic system of registries. It was constructed by linking the population-based twin registries of Denmark, Finland, Norway and Sweden to their country-specific national cancer and cause-of-death registries. These linkages enable the twins to be followed many decades for cancer incidence and mortality. To date, two major linkages have been conducted: NorTwinCan I in 2011–2012 and NorTwinCan II in 2018. Overall, there are 315,413 eligible twins, 57,236 incident cancer cases and 58 years of follow-up, on average. In the initial phases of our work, NorTwinCan established the world’s most comprehensive twin database for studying cancer, developed novel analytical approaches tailored to address specific research considerations within the context of the Nordic data and leveraged these models and data in research publications that provide the most accurate estimates of heritability and familial risk of cancers reported in the literature to date. Our findings indicate an excess familial risk for nearly all cancers and demonstrate that the incidence of cancer among twins mirrors the rate in the general population. They also revealed that twin concordance for cancer most often manifests across, rather than within, cancer sites, and we are currently focusing on the analysis of these cross-cancer associations.
Nonideal Electric Field Observed in the Separatrix Region of a Magnetotail Reconnection Event
Authors: Yu Xiancai , Wang Rongsheng , Lu Quanming , Russell Christopher T. , Wang Shui 
Published: September 2019

AbstractBased on the Magnetospheric Multiscale observations in the magnetotail, we present a complete crossing of the current sheet with ongoing magnetic reconnection. The field‐aligned inflowing electrons were observed in both separatrix regions (SRs) and their energy extended up to several times of the thermal energy. Along the SR, a net parallel electrostatic potential was estimated and could be the reason for the inflowing electron streaming. In the northern SR, the electron frozen‐in condition was violated and nonideal electric field was inferred to be caused by the gradient of the electron pressure tensor. The nongyrotropic electron distribution and significant energy dissipation were observed at the same region. The observations indicate that the inner electron diffusion region can extend along the separatrices or some electron‐scale instability can be destabilized in the SR.
Radiative Effect of Mineral Dust on East Asian Summer Monsoon During the Last Glacial Maximum: Role of Snow‐Albedo Feedback
Authors: Shi Zhengguo , Xie Xiaoning , Ren Xin , Li Xinzhou , Yang Liu , Lei Jing , Liu Xiaodong , An Zhisheng 
Published: September 2019

AbstractMineral dust exerts great influence on modern climate. Eolian deposits reveal that atmospheric dust concentration is larger during the Last Glacial Maximum, especially over Asia. However, the larger forcing of dust on Asian climate is still not fully explored. In this study, climate model experiments are conducted to evaluate the direct radiative effect on East Asian monsoon. The results show that the radiative forcing of dust, amplified by snow albedo feedback over high‐latitude Eurasia, produces a wave‐like pattern in westerlies and weakens the monsoon southerly winds over northern China. Dust over expanded Last Glacial Maximum sources (northern Central Asia and northeastern Russia) is responsible for this perturbation of the westerlies; the absence of these dust sources at present explains why such impacts on circulations are not simulated for modern conditions. The dust‐induced anomalies in southerly wind speed and precipitation over northern China reach 29% and 41% of the glacial‐induced changes, respectively.
PM2.5 Pollution Modulates Wintertime Urban Heat Island Intensity in the Beijing‐Tianjin‐Hebei Megalopolis, China
Authors: Yang Yuanjian , Zheng Zuofang , Yim Steve Y.L. , Roth Matthias , Ren Guoyu , Gao Zhiqiu , Wang Tijian , Li Qingxiang , Shi Chune , Ning Guicai , Li Yubin 
Published: September 2019

AbstractHeavy PM2.5 (particulate matter with aerodynamic diameter equal to or less than 2.5 μm) pollution and urban heat island (UHI) pose increasing threats to human health and living environment in populated cities. However, how PM2.5 pollution affects the UHI intensity (UHII) has not been fully understood. The impacts of PM2.5 on the wintertime UHII in the Beijing‐Tianjin‐Hebei megalopolis of China are explored during 2013–2017. The results show that the UHII at the time of daily maximum/minimum temperature (UHIImax/UHIImin) exhibits a decreasing/increasing tendency as PM2.5 concentration increases, causing a continuous decrease in the diurnal temperature range. These effects are mediated via aerosol‐radiation interaction (aerosol‐cloud interaction) under clear‐sky (cloudy) condition. The changes in PM2.5 concentration further cause different relative trends of UHIImax/UHIImin/diurnal temperature range across different cities in the Beijing‐Tianjin‐Hebei region, which are likely related to the differences in both the PM2.5 composition and city size. This study provides insights on how air pollution affects urban climate and would help to design effective mitigation strategies.
Solar Flare Effects on 150‐km Echoes Observed Over Jicamarca: WACCM‐X Simulations
Authors: Pedatella N. M. , Chau J. L. , Vierinen J. , Qian L. , Reyes P. , Kudeki E. , Lehmacher G. , Oppenheim M. 
Published: September 2019

AbstractJicamarca Radio Observatory observations and Whole Atmosphere Community Climate Model with thermosphere‐ionosphere eXtension (WACCM‐X) simulations are used to investigate the effects of the 7 September 2005 X‐17 solar flare on 150‐km echoes, electron densities, and vertical plasma drifts. The solar flare produces a remarkably similar response in the observed 150‐km echoes and simulated electron densities. The results provide additional evidence of the relationship between the background electron density and the layering structure that is seen in 150‐km echoes. The simulations also capture a similar rapid decrease in vertical plasma drift velocity that is seen in the observations. The simulated change in vertical plasma drift is, however, weaker than the observed decrease at the longitude of Jicamarca, though it is stronger east of Jicamarca. The effect of the solar flare on the vertical plasma drifts is primarily attributed to changes in conductivity due to the enhanced ionization during the solar flare.
Influence of Grain Boundary Structural Evolution on Pressure Solution Creep Rates
Authors: van den Ende M. P. A. , Niemeijer A. R. , Spiers C. J. 
Published: September 2019

AbstractIntergranular pressure solution is a well‐known rock deformation mechanism in wet regions of the upper crust and has been widely studied, especially in the framework of compaction of granular materials, such as reservoir sandstones and fault rocks. Several analytical models exist that describe compaction creep by stress‐induced mass transport, and the parameters involved are relatively well constrained by laboratory experiments. While these models are capable of predicting compaction behavior observed at relatively high porosities, they often overestimate compaction rates at porosities below 20% by up to several orders of magnitude. This suggests that the microphysical processes operating at low porosities are different and are not captured well by existing models. The implication is that available models cannot be extrapolated to describe compaction of sediments and fault rocks to the low porosities often reached under natural conditions. To address this problem, we propose a new, thermodynamic model that describes the decline of pressure solution rates within individual grain contacts as a result of time‐averaged growth of asperities or islands and associated constriction of the grain boundary diffusion path (here termed grain boundary evolution). The resulting constitutive equations for single grain‐grain contacts are then combined and solved semianalytically. The compaction rates predicted by the model are compared with those measured in high‐strain compaction experiments on wet granular halite. A significant reduction in compaction rate is predicted when grain boundary evolution is considered, which compares favorably with the experimental compaction data.
An Experimental Study of Matrix Dissolution and Wormhole Formation Using Gypsum Core Flood Tests: 2. Dissolution Kinetics and Modeling
Authors: Li Wei , Einstein Herbert H. , Germaine John T. 
Published: September 2019

AbstractIn the parallel paper by Li et al. (2019; https://doi.org/10.1029/2018JB017238), an effluent chemistry monitoring system was designed and used in core flood experiments to continuously measure the effluent concentration and study the evolution of the rock‐fluid system. In this study, the results from the parallel paper were used for interpretation and modeling of the dissolution and wormhole formation. Based on the behavior of the effluent concentration, two transient states and two quasi‐steady states were defined to describe the dissolution in the rock‐fluid system. Dimensional analysis was used to identify the controlling mechanisms of the dissolution and transport in the matrix and the wormholes. The dimensional analysis showed that the dissolution in the matrix was reaction controlled, while the dissolution in the wormholes was diffusion controlled. It also showed that the rock‐fluid system evolved from reaction‐controlled dissolution to diffusion‐controlled dissolution during the core flood tests. A continuum model and the extended Graetz solution were used to model the dissolution in the matrix and in the wormholes, respectively. In the continuum model, this study estimates the effective surface area as a function of the flow rate (injection flux), to account for the effect of flow conditions on dissolution. Finally, a semiempirical model combining the continuum model and the extended Graetz solution was developed to simulate the formation of wormholes and the evolution of the dissolution kinetics during core flood tests.
The Malvinas Current at the Confluence With the Brazil Current: Inferences From 25 Years of Mercator Ocean Reanalysis
Authors: Artana Camila , Provost Christine , Lellouche Jean‐Michel , Rio Marie‐Hélène , Ferrari Ramiro , Sennéchael Nathalie 
Published: September 2019

AbstractTwenty‐five years of high‐resolution (1/12°) ocean reanalysis are used to examine the Confluence of the Malvinas Current (MC) with the Brazil Current (BC) from synoptic to interannual time scales. The model transports of the MC (38.0 Sv ± 7.4 Sv 57 at 41°S) and the BC (23.0 Sv ± 11 Sv at 36°S) agree with observations. The model shows the branching of the MC near the Confluence with an offshore branch returning south and an inner branch sinking below the BC and managing to continue northward along the continental slope. Northward velocities associated with the subsurface inner branch peak at 40 cm/s at 36°S at 700‐m depth. The model documents the migrations of the Subantarctic (SAF) and Subtropical Fronts (STF) at the Confluence. The SAF and STF positions vary over a large range at synoptic (800 km) and interannual scale (300 and 200 km, respectively) compared to the rather small seasonal migrations of the STF (150 km) and SAF (50 km). While trends in the MC are small over the 25 years of the reanalysis, the BC becomes more intense (12.5 cm/s), saltier (0.37 psu), and warmer (2.5°C) in the upper 1,000 m. These trends are accompanied with a southward displacement of the STF and the SAF of 150 and 50 km.
Progressive Evolution of the Changjiang (Yangtze River) Sediment Weathering Intensity Since the Three Gorges Dam Operation
Authors: Yang Chengfan , Yang Shouye , Song Jiaze , Vigier Nathalie 
Published: September 2019

AbstractChemical composition of river sediments and dissolved load is classically used to infer controls on continental weathering and, therefore, exert an important role on the understanding of the global carbon and biogeochemical cycles. To date, most studied river basins are strongly impacted by dam constructions; however, the effects of dams on sediment chemical compositions are little known. The Three Gorges Dam is one of the largest dams in the world and began impounding water in 2003 in the Changjiang basin. In order to investigate the impact of this dam on downstream sediment chemistry, temporal variation of sediment weathering intensity is reported here based on analyzed and compiled data between 1997 and 2018. Downstream sediments collected before 2003 are characterized by weak weathering intensity, in agreement with the overwhelming flux and fast transfer of sediments derived from the mountainous upper watershed. After the Three Gorges Dam operation, strong midlower riverbed erosion changed the roles of the midlower reaches from important sinks to major sources of sediments delivered to the East China Sea. This resulted in a progressive change of the sediment chemistry because the eroded midlower riverbed sediments were more deeply weathered, as confirmed by 150‐year‐old sediment cored in the lower mainstream and by mass‐balance calculations. This more intensive weathering may be explained by warmer climate and longer water‐rock interaction time in the midlower basin. Thus, this study suggests the need to quantify potential bias in weathering intensity and controls caused by damming activity in large river systems.