bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and socio-demographic characteristics associated with involuntary admissions in Switzerland between 2008 and 2016: An observational cohort study before and after implementation of the new legislation
Authors: Hotzy Florian , Hengartner Michael P. , Hoff Paul , Jaeger Matthias , Theodoridou Anastasia 
Published: May 2019

AbstractBackground:Involuntary admission (IA) for psychiatric treatment has a history of controversial discussions. We aimed to describe characteristics of a cohort of involuntarily compared to voluntarily admitted patients regarding clinical and socio-demographic characteristics before and after implementation of the new legislation.Methods:In this observational cohort study, routine data of 15’125 patients who were admitted to the University Hospital of Psychiatry Zurich between 2008 and 2016 were analyzed using a series of generalized estimating equations.Results:At least one IA occurred in 4’560 patients (30.1%). Of the 31’508 admissions 8’843 (28.1%) were involuntary. In the final multivariable model, being a tourist (OR = 3.5) or an asylum seeker (OR = 2.3), having a schizophrenic disorder (OR = 2.1), or a bipolar disorder (OR = 1.8) contributed most to our model. Male gender, higher age, prescription of neuroleptics (all OR < 2.0) as well as having a depressive disorder, prescription of psychotherapy, prescription of antidepressants and admission after implementation of the new legislation (all OR > 0.6) were also weakly associated with IA.Conclusions:Besides schizophrenic or bipolar disorders, a small group of patients had an increased risk for IA due to non-clinical parameters (i.e. tourists and asylum seekers). Knowledge about risk factors should be used for the development of multi-level strategies to prevent frequent (involuntary) hospitalizations in patients at risk. On the organizational level, we could show that the new legislation decreased the risk for IA, and therefore may have succeeded in strengthening patient autonomy.
The effect of eye images and a social norms message on healthcare provider hand hygiene adherence
Authors: Stella Sarah A. , Stace Roger J. , Knepper Bryan C. , Reese Sara M. , Keniston Angela , Burden Marisha , Young Heather L. 
Published: May 2019

AbstractBackground:Depictions of eye images and messages encouraging compliance with social norms have successfully motivated behavioral change in a variety of experimental and applied settings. We studied the effect of these 2 visual cues on hand hygiene adherence in a cohort of hospital-based healthcare providers participating in an electronic monitoring and feedback program.Methods:Prospective, quasi-experimental study utilizing an interrupted time-series design. Intervention placards depicting an image of eyes, a social norms message, or a control placard were placed near soap and alcohol-based hand-rub dispensers on 2 hospital units. Placards were alternated every 10 days. Hand hygiene opportunities and adherence rates were assessed electronically via the CenTrak Hand Hygiene Compliance Solution.Results:A total of 166 nurses and certified nursing assistants (74 on a medical-surgical unit and 92 on a progressive care unit) were monitored electronically over the 4-month study period. In total, 184,172 electronic observations were collected (110,903 on a medical-surgical unit and 73,269 on a progressive care unit). The median daily number of electronic observations was 1,471 (interquartile range, 1,337–1,584). The preintervention baseline hand hygiene adherence rate was 70%. No statistically significant increase in hand hygiene adherence was observed as a result of either intervention.Conclusion:Displaying eye images or a social norms message in the hospital environment did not result in measurable improvements in HH adherence in a cohort of healthcare providers participating in an electronic monitoring and feedback program.
Three-dimensional wakes behind cylinders of square and circular cross-section: early and long-time dynamics
Authors: Agbaglah G. , Mavriplis C. 
Published: May 2019

The flow in the near wake of a square cylinder at Reynolds numbers of 205 and 225, corresponding to three-dimensional wake instability modes $A$ and $B$, respectively, and that of the square’s circumscribed circular cylinder are examined by using three-dimensional Navier–Stokes numerical simulations. At small times, prior to the streamwise vortex shedding, a self-similar velocity is observed in the wake and no significant difference is observed in the dynamics of the flows past the square and the circular cylinders. The exponential growth of the three-dimensional instability reaches a saturation regime during this early time for the considered Reynolds numbers. Vortical structures in the wake at long times and shedding frequencies are very close for the square and the circular cylinders. The flow separation on the forward top and bottom corners of the square cylinder have the effect of increasing its effective width, making it comparable with the diameter of the circumscribed circular cylinder. Thus, Floquet multipliers and modes of the associated three-dimensional instabilities are shown to be very close for the two cylinders when using the circumscribed circular cylinder as the basis for a characteristic length scale. Most importantly, the wavenumber with the maximum growth rate, for modes $A$ and $B$, is approximately identical for the two cylinders.
Bridging the pond: measuring policy positions in the United States and Europe
Authors: Struthers Cory L. , Hare Christopher , Bakker Ryan 
Published: May 2019

AbstractRecent work has pioneered the use of expert surveys to estimate cross-national party positions in a common ideological space. In this paper, we report findings from an original dataset designed to evaluate bridging strategies between European and American party placements. Specifically, we compare the use of “anchoring vignettes” (fictional party platforms) with an alternative approach that asks comparativist scholars who live in the US (whom we call transatlantic or TA experts) to place parties and parties in their country of expertise on a series of issues scales. The results provide an optimistic assessment of the ability of TA experts to serve as valid bridges across the Atlantic. The resulting cross-comparable estimates of party positions show instances of both convergence and divergence between American and European party systems, including parallels between systems on the cross-cutting issue of international economic integration.
MALICE AS AN INGREDIENT OF TORT LIABILITY
Authors: Murphy John 
Published: May 2019

AbstractThis article is concerned with the question of whether malice is an appropriate touchstone of liability in tort law. It begins by identifying four torts in which malice may properly be regarded as an ingredient of liability (distinguishing various other torts, such as private nuisance and defamation, in which malice plays a merely secondary and contingent role). Having identified these four torts – namely malicious prosecution, abuse of process, misfeasance in a public office and lawful means conspiracy – the article then seeks to identify a common juridical thread which links them together. So doing serves to rebut the allegation, often made in respect of all them, namely, that they are anomalous actions. It then concludes by considering the individual worth of these torts, bearing in mind the important difference between not being anomalous on the one hand, and being positively meritorious on the other. It concludes that a respectable defence of each of the four torts can be made even though malice is an atypical touchstone of liability.
The aspartic proteinase is expressed inArabidopsis thalianaseeds and localized in the protein bodies
Authors: Mutlu Asuman , Chen Xia , M. Reddy Sridhar , Gal Susannah 
Published: May 2019

AbstractWe have been studying a seed aspartic proteinase, termed AtAP, fromArabidopsis thaliana.In previous work, we purified the proteinase, analysed its activity and isolated the cDNA sequence. In this paper, the expression of the mRNA for the aspartic proteinase was analysed in seed tissues both by Northern blots for overall regulation and byin situhybridization to follow cell-specific localization of message. We found a 1.9 kb aspartic proteinase message in dry seeds and seed pods. This message was expressed in many different cell types of the mature dry seed. The localization of the protein within these cells was also determined. Antibodies were raised against the AtAP and purified using affinity chromatography on an AtAP–immobilized-pepstatin A–agarose column. This purified antibody recognized several AtAP peptides in seeds. To localize the enzyme in cells, we isolated protein bodies from the dry seeds of Arabidopsis using a non-aqueous isolation method. The AtAP activity and antigenic peptides were found to be highest in the protein body fraction and co-localized with the seed storage protein 2S albumin and the vacuolar marker enzyme α-mannosidase. This protein body localization of the AtAP was confirmed with immunocytochemical localization by electron microscopy and shows that the protein is not secreted by these cells.
Internal anatomy of individual tomato seeds: relationship to abscisic acid and germination physiology
Authors: Downie Bruce , Gurusinghe Sunitha , Bradford Kent J. 
Published: May 2019

AbstractTomato seeds that have been dried, imbibed and redried (primed) develop internal free space between the embryo and endosperm. Seeds of the ABA-deficient sitiens(sitw) tomato mutant can exhibit internal free space at the completion of seed development even without priming. Both primed and sitwseeds germinate more rapidly than untreated wild-type seeds. To determine whether internal anatomy predicts germination physiology, individual sitwand primed wild-type seeds were sorted into three categories based upon the extent of internal free space observed non-destructively using X-radiography. Category 3 (C3, extensive free space present) sitw seeds completed germination more rapidly than all other seed categories and genotypes in water, in abscisic acid (ABA) or under far-red illumination. The force necessary to puncture the endosperm caps (and testa) of C3 sitw seeds was less, and the percentage of nuclei in C3 sitw radicle tips in the G2 stage of the cell cycle was greater than for all other seed categories. Wild-type seeds exhibited free space following long-term priming, but germination was still prevented by far-red light and ABA, and endosperm cap strength and nuclear DNA contents were not altered. Endo-β-mannanase activity of individual endosperm caps was not consistently related to their resistance to puncture. While internal free space is diagnostic for primed tomato seeds and occurs in a fraction of sitw seeds, it is not predictive of many aspects of germination physiology.
Desiccation sensitivity and activities of free radical-scavenging enzymes in recalcitrant Theobroma cacao seeds
Authors: Li Changrun , Sun Wendell Q. 
Published: May 2019

AbstractMature and immature axes of Theobroma cacao (cocoa) seeds tolerated desiccation under a rapid-drying regime to critical water contents of 1.0 and 1.7 g g-1 dw, respectively. These critical water contents corresponded to water contents below which activities of free radical-scavenging enzymes (ascorbate peroxidase, peroxidase and superoxide dismutase) decreased rapidly during desiccation. The decline in axis viability below the critical water content was correlated with sharp increases in lipid peroxidation and cellular leakage. Cotyledon tissues were more desiccation-tolerant than axes, with a low critical water content of 0.24 g g–1dw. Desiccation sensitivity in cotyledon tissues was also correlated with the decrease in superoxide dismutase activity and increased lipid peroxidation products. However, in the cotyledons, no ascorbate peroxidase activity was detected at any water content, and peroxidase activity was gradually reduced as desiccation proceeded. Cocoa embryonic axes contained large amounts of sucrose, raffinose and stachyose but only traces of reducing monosaccharides. Desiccation sensitivity of recalcitrant cocoa axes did not appear to be due to the lack of sugar-related protective mechanisms during desiccation, and it was more likely related to the decrease of enzymic protection against desiccation-induced oxidative stresses.
Triage, Transportation, and Destination Decisions by Out-of-Hospital Emergency Care Providers
Authors: Billittier Anthony J. , Lerner E. Brooke , Moscati Ronald M. , Young Gregory 
Published: May 2019

AbstractIntroduction:The effectiveness of a tiered emergency medical services system often hinges upon the ability of initial care providers with little or no formal training to identify emergent patient needs and determine the best means to meet those needs.Objectives:To determine if out-of-hospital emergency care providers consistently make appropriate triage, transportation, and destination decisions; and to determine if experience and training have an effect on these decisions.Methods:A survey consisting of 14 patient-care scenarios was administered to certified and non-certified out-of-hospital emergency-care providers (n = 311) from 20 randomly selected EMS agencies. These agencies were part of EMS systems that utilize one, two, and three tiered responses by ambulance and fire-based commercial, municipal, and volunteer agencies. Participants were asked to select the most appropriate mode of transport and destination facility using the assumption that they had responded to each scenario in a basic life support ambulance. Answers included transporting the patient to various receiving facilities or requesting a more advanced-level unit to respond to the scene. Transport times to receiving facilities and estimated times of arrival for advanced-level units were provided with each choice. Eight emergency physicians unanimously had agreed upon the most appropriate answer for each scenario. A two-tailed t-test was used to compare the scores of the certified and non-certified groups; and Spearman's Correlation Coefficients were used to test the effects of experience and training.Results:Non-certified providers (n = 108) had a mean score of 32.6% or 4.6 (SD = 1.84) correct answers; certified providers (n = 203) had a mean score of 41.1% or 5.76 (SD = 2.12) correct answers (p < 0.000001). Spearman's Correlation Coefficients were: 1) individual provider level - (0.3978); 2) agency provider level - (0.2741); 3) hours workea per week - (0.2505); 4) years in EMS - (- 0.0821); 5) commercial or volunteer provider - (0.2398); 6) agency call volume - (0.2012); 7) agency location - (0.0685), and 8) transporting versus non-transporting agency - (0.2523).Conclusion:A need exists for further education of out-of-hospital emergency care providers with respect to triage, transportation, and destination decisions. Provider experience and level of certification do not appear to affect these critical patient-care decisions.
Predicting Survival From Out-of-Hospital Cardiac Arrest
Authors: Lindholm Daniel J. , Campbell Jack P. 
Published: May 2019

AbstractObjective:To determine the effect of a return of spontaneous circulation (RO SC) on survival to hospital discharge as compared to other established predictors of survival.Methods:A retrospective case review of all out-of-hospital primary cardiac arrests from 01 January, 1992 to 31 December 1994 was conducted. The relative values of age, race, gender, presenting cardiac rhythm, witnessed event, initiation of CPR by bystanders, response time intervals, and return of spontaneous circulation (ROSC) in an Utstein-template database were tested as predictors of survival of patients who had suffered a cardiac arrest in the out-of-hospital setting. The ROSC was defined as return of spontaneous circulation prior to and present upon arrival at the emergency department. Predictors were evaluated for statistical significance using a logistic regression analysis (p < 0.05). Odds ratios (OR) and 95% confidence intervals (CI) with positive and negative predictive values (PPV, NPV) were calculated.Results:Of 832 patients with primary cardiac arrest, 153 (18.4%) had ROSC and 67 (8.1%) survived to hospital discharge. Comparing survivors to nonsurvivors, the mean values for age were 64 to 67 years, with 59.7% to 36.1% being witnessed, 35.8% to 23.9% having bystander CPR initiated, 88.1% to 48.4% having ventricular fibrillation (V-fib) and 82.1% to 64.0% having ROSC. An initial electro-cardiographic rhythm of V-fib (p = 0.009; OR = 2.2; CI = 1.2-3.9), and ROSC (p < 0.0001; OR = 5.2; CI = 3.6-7.5) are statistically significant predictors of survival to hospital discharge. The PPV was 13.8% for V-fib and 35.9% for ROSC, and the NPV was 98.0% for V-fib and 98.2% for ROSC.Conclusion:Presenting V-fib and out-of-hospital ROSC are significant predictors of survival from cardiac arrest. Failure to obtain ROSC in the out-of-hospital setting strongly suggests consideration for terminating resuscitation efforts.
A Classroom Simulation of the Syrian Conflict
Authors: Frank Richard W. , Genauer Jessica 
Published: May 2019

ABSTRACTThis article describes a semester-long classroom simulation of the Syrian conflict designed for an introductory international relations (IR) course. The simulation culminates with two weeks of multi-stakeholder negotiations addressing four issues: humanitarian aid, economic sanctions, ceasefire, and political transition. Students randomly play one of 15 roles involving three actor types: states, non-state actors, and international organizations. This article outlines the costs and benefits of simulation design options toward encouraging students’ understanding of IR concepts, and it proposes a course plan for tightly integrating lectures, readings, assessment, and simulation—regardless of class size or length. We highlight this integration through a discussion of two weeks’ worth of material—domestic politics and war, and non-state actors—and the incorporation of bargaining concepts and frameworks into the two weeks of simulated multi-stakeholder negotiations.
Recent advances in research on draught ruminants
Authors: Pearson R. A. , Zerbini E. , Lawrence P. R. 
Published: May 2019

AbstractA feeding system, draught cows, disease/work interactions and animal power introduction in a farming system, four areas of recent research on draught ruminants which are important to future development of animal power, are reviewed. A new feeding system for draught animals is described which enables food requirements and the effects of work on live weight and milk production to be calculated.Recent data on the energy cost of walking are appraised. Research on working cows, mainly in Ethiopia, has shown that undernutrition has a greater effect on milk yield than work, which has a transient effect. The length of the post-partum anoestrous period increases with decrease in body condition. Body-weight loss increases with increasing work load. It is suggested that dairy cows delay conception by 1 day for every day of work done. Work has little effect on food intake or digestive parameters. Although it is associated with an overall increase in food intake of cows, even of un-supplemented forage diets, the increase is not sufficient to meet all the extra energy needs for work. Food intake of both working and non-working cows increases during lactation.Disease limits the working capacity of draught animals and work can exacerbate disease. These effects were investigated using Trypanosoma evansi in Indonesia and T. congolense in The Gambia. In both studies, infected animals were able to do much less work than non-infected ones and the severity of the effect depended greatly on the strain of trypanosome used. In general, increasing the plane of nutrition did not ameliorate the effects of the disease, nor in the Gambian study did it prevent loss of appetite in infected animals.The technical and agronomic innovations necessary for the introduction of animal power into an inland valley region of central Nigeria are described and some of the sociological implications discussed.
Genetic and phenotypic parameter estimates for feeding pattern and performance test traits in pigs
Authors: Hall A. D. , Hill W. G. , Bampton P. R. , Webb A. J. 
Published: May 2019

AbstractThe data used in these analyses were compiled from individual feeding records of 1832 pigs from 70 sire families using FIRE (food intake recording equipment) system from Hunday Electronics Ltd at the Cotswold Pig Development Company. Pigs were on test between 45 (s.d. 2·76) kg and 95 (s.d. 6·78) kg. Daily food intake (DFI kg), food intake per visit (FlV kg), number of visits per day (NV), duration of each visit (TV min), time in the feeder per day (TD min), feeding rate (FR kg/min) and number of non-feeding visits per day (NFV), were measured as means of test and DFI was also recorded as means of bi-weekly periods of test. Performance test traits ofbackfat depth off test (BF mm), food conversion ratio (ECR kg/kg) and average daily gain (ADG kg), over the test period, were also measured.Parameters were estimated by restricted maximum likelihood with a multivariate individual animal model. DFI had a heritability of 0·21 ranging from 0·18 to 0·26 over the four test periods. Correlations between DFI in each test period were high (rg = 0·75 to 0·99). DFI was highly correlated with performance test traits (0·61 to 0·78) but had low correlations with feeding pattern traits (0·0 to 0·24). The heritabilities of feeding pattern traits were low (0·06 to 0·11) with the exception of FIV (0·27) and NV (0·34) but correlations between feeding pattern traits were high. FIV, NV and TV were moderately correlated with ADG (rg = 0·49, -0·29, 0·33 respectively), BF (rg = 0·35, -0·15, 0·17 respectively) and ECR (rg = -0·12, 0·31, -0·27 respectively). Feeding patterns may be changed substantially by selection and the genetic correlations with performance test traits indicate that feeding patterns traits can be usefully incorporated in selection criteria to improve somewhat the accuracy of selection.
A genetic and economic analysis of nucleus breeding plans designed to improve dairy breeds in Brazil
Authors: Lobo C. H. , Allaire F. R. 
Published: May 2019

AbstractThe objective of this research was to design and compare nucleus breeding plans that might be recommended to the breeders of Brazilian dairy cattle. Plans for native dairy breeds were compared for the change of genetic merit in milk yield and in the economic return at 25-year investment periods. Effects of nucleus herd and commercial population sizes on genetic gain and net income were examined. Investment value of plans was studied for differences in the efficiency of embryo transfer techniques and in the sale price of cows and young bulls on genetic merit. Parent selection was based on records on individuals (for females), their full- and half-sibs, their dam, full-and half-sibs of their sire and their dam and their grandam. Within herd sire selection was restricted to a maximum of one bull per full-sib family. No matings of full-sibs were allowed. Annual economic summaries considered the age distribution of animals within herds. Alternative plans were investigated for their revenue, expense and net income streams and their investment value. The cumulative genetic gain of selected animals in lactational milk production was 1639 kg and 1435 kg for large plans with 64 donors (L) and small plans with 32 donors (S), respectively. The initial genetic lift for a population size of 20 000 animals was equal to 279 kg. When the size of the commercial population was increased to 50 000 animals, the lift was increased by 10%. Profitability in the different plans was achieved after the sale of cows and young bulls. The difference between cumulative discounted net returns at year 25 for L and S was proportional to the sale prices placed on the genetic merit of cows and bulls. The programmes of genetic improvement described were profitable and should be recommended to the breeders of Brazilian dairy cattle. Considering the criteria of gain to cost, the smaller plan seems to be the most reasonable to implement.