bluuebunny/crossref_metadata_2025_split huggingface dataset:
Male Sex, Decreased Activity Level, and Higher BMI Associated With Lower Completion of Patient-Reported Outcome Measures Following ACL Reconstruction
Authors: Cotter Eric J. , Hannon Charles P. , Locker Philip , Davey Annabelle , Wang Kevin C. , Verma Nikhil N. , Cole Brian J. 
Published: March 2018

Background: Patient-reported outcome (PRO) surveys have become increasingly important in both improving patient care and assessing outcomes. Purpose/Hypothesis: The purpose of this study was to evaluate which variables are associated with compliance with completing PRO surveys in patients who have undergone anterior cruciate ligament reconstruction (ACLR). The authors hypothesized that older patient age and longer time since ACLR would be associated with lower completion rates of PRO surveys preoperatively and at postoperative time points. Study Design: Case series; Level of evidence, 4. Methods: All patients who underwent ACLR by a sports medicine fellowship–trained orthopaedic surgeon at a single institution and were electronically assigned PRO surveys through a data collection system preoperatively between December 2013 and March 2015 were included. Postoperatively, PRO surveys were sent to patients’ email addresses at 6, 12, and 24 months. Demographics, history, and operative and postoperative information were evaluated for an association with survey completion rates. Results: A total of 256 patients met the inclusion criteria. There were 140 (54.7%) male and 116 (45.3%) female patients, with an overall mean age of 28.6 ± 11.9 years. Only 19 (7.4%) patients completed all preoperative and postoperative surveys at all time points. Less than half of the patients (n = 104; 40.6%) completed both the preoperative survey and at least 1 postoperative survey. There was a steady decrease in the completion rate of PRO surveys postoperatively over time (Pearson r = –0.995, P = .005). Male patients had significantly worse compliance with completing PRO surveys preoperatively and at a minimum of 1 time point postoperatively ( P = .044). Patients who did not identify as athletes or report frequent exercise (≥3 times/wk) had significantly worse compliance with completing any PRO surveys ( P = .046). Lower body mass index was associated with greater odds of compliance with completing the preoperative survey and 24-month postoperative survey (odds ratio, 0.902; P = .029). Conclusion: An inverse relationship was found between the surgery-to-survey period and percentage of those completing PRO surveys, with poor overall compliance. Male sex and not self-identifying as an athlete or performing frequent physical exercise were associated with lower completion rates of PRO surveys, while lower body mass index was associated with a greater rate of completion.
Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm
Authors: Xiao Pingnan , Dolinska Monika , Sandhow Lakshmi , Kondo Makoto , Johansson Anne-Sofie , Bouderlique Thibault , Zhao Ying , Li Xidan , Dimitriou Marios , Rassidakis George Z. , Hellström-Lindberg Eva , Minato Nagahiro , Walfridsson Julian , Scadden David T. , Sigvardsson Mikael , Qian Hong 
Published: March 2018

Key Points
Sipa1 loss leads to BM niche alterations prior to the initiation of MPN. Sipa1-deficient BM niche induces lethal MPN from normal hematopoietic cells.
Rationale and design of the screening of pulmonary hypertension in systemic lupus erythematosus (SOPHIE) study
Authors: Huang Duo , Cheng Yang-Yang , Chan Pak-Hei , Hai Jojo , Yiu Kai-Hang , Tse Hung-Fat , Wong Ka-Lam , Fan Katherine , Li Ying Wah , Ng Woon-Leung , Yim Cheuk-Wan , Wong Cheuk-hon John , Tam Lai-Shan , Wong Priscilla C.H. , Wong Chi-Yuen , Ho Chup-Hei , Leung Alexander M.H. , Mok Chi-Chiu , Lam Ho , Lau Chak-Sing , Cheung Tommy , Ho Carmen , Law Sharon W.Y. , Chan Esther W. , Yin Li-Xue , Yue Wen-Sheng , Mok Toi Meng , Evora Mario Alberto , Siu Chung-Wah 
Published: March 2018

Current guideline-recommended screening for pulmonary hypertension in patients with systemic sclerosis has not been evaluated in systemic lupus erythematosus (SLE), which is disproportionately prevalent in Asians.This multicentre, cross-sectional screening study aims to study the prevalence of pulmonary hypertension among SLE patients using these guidelines, and identify independent predictors and develop a prediction model for pulmonary hypertension in SLE patients.SLE patients from participating centres will undergo an echocardiography- and biomarker-based pulmonary hypertension screening procedure as in the DETECT study. Standard right heart catheterisation will be provided to patients with intermediate or high echocardiographic probability of pulmonary hypertension. Those with low echocardiographic probability will rescreen within 1 year. The primary measure will be the diagnosis and types of pulmonary hypertension and prevalence of pulmonary hypertension in SLE patients. The secondary measures will be the predictors and prediction models for pulmonary hypertension in SLE patients. The estimated sample size is approximately 895 participants.The results of the SOPHIE study will be an important contribution to the literature of SLE-related pulmonary hypertension and may be immediately translatable to real clinical practice. Ultimately, this study will provide the necessary evidence for establishing universal guidelines for screening of pulmonary hypertension in SLE patients.
Glycemic variability in continuous glucose monitoring is inversely associated with baroreflex sensitivity in type 2 diabetes: a preliminary report
Authors: Matsutani Daisuke , Sakamoto Masaya , Iuchi Hiroyuki , Minato Souichirou , Suzuki Hirofumi , Kayama Yosuke , Takeda Norihiko , Horiuchi Ryuzo , Utsunomiya Kazunori 
Published: March 2018

Abstract
Background
It is presently unclear whether glycemic variability (GV) is associated with baroreflex sensitivity (BRS), which is an early indicator of cardiovascular autonomic neuropathy. The present study is the first to examine the relationships between BRS and GV measured using continuous glucose monitoring (CGM).

Methods
This was a multicenter, prospective, open-label clinical trial. A total of 102 patients with type 2 diabetes were consecutively recruited for this study. GV was assessed by measuring the standard deviation (SD), glucose coefficient of variation (CV), and the mean amplitude of glycemic excursions (MAGE) during CGM. The BRS was analyzed from electrocardiogram and blood pressure recordings using the sequence method on the first day of hospitalization.

Results
A total of 94 patients (mean diabetes duration 9.7 ± 9.6 years, mean HbA1c 61.0 ± 16.8 mmol/mol [7.7 ± 1.5%]) were analyzed. In the univariate analysis, CGM-SD (r = − 0.375, p = 0.000), CGM-CV (r = − 0.386, p = 0.000), and MAGE (r = − 0.395, p = 0.000) were inversely related to BRS. In addition to GV, the level of BRS correlated with the coefficient of variation in the R–R intervals (CVR-R) (r = 0.520, p = 0.000), heart rate (HR) (r = − 0.310, p = 0.002), cardio-ankle vascular index (CAVI) (r = − 0.326, p = 0.001), age (r = − 0.519, p = 0.000), and estimated glomerular filtration rate (eGFR) (r = 0.276, p = 0.007). Multiple regression analysis showed that CGM-CV and MAGE were significantly related to a decrease in BRS. These findings remained after adjusting the BRS for age, sex, hypertension, dyslipidemia, HR, eGFR, CAVI, and CGM-mean glucose. Additionally, BRS was divided according to quartiles of the duration of diabetes (Q1–4). BRS decreased after a 2-year duration of diabetes independently of age and sex.

Conclusions
GV was inversely related to BRS independently of blood glucose levels in type 2 diabetic patients. Measurement of BRS may have the potential to predict CV events in consideration of GV.
Trial registration UMIN Clinical Trials Registry UMIN000025964, 28/02/2017
Variability in Case Durations for Common Surgical Procedures
Authors: Glance Laurent G. , Dutton Richard P. , Feng Changyong , Li Yue , Lustik Stewart J. , Dick Andrew W. 
Published: March 2018

BACKGROUND:
Under the Merit-based Incentive Payment System, physician payment will be adjusted using a composite performance score that has 4 components, one of which is resource use. The objective of this exploratory study is to quantify the facility-level variation in surgical case duration for common surgeries to examine the feasibility of using surgical case duration as a performance metric.

METHODS:
We used data from the National Anesthesia Clinical Outcomes Registry on 404,987 adult patients undergoing one of 6 general surgical or orthopedic procedures: laparoscopic appendectomy, laparoscopic cholecystectomy, laparoscopic cholecystectomy with intraoperative cholangiogram, knee arthroscopy, laminectomy, and total hip replacement. We constructed separate mixed-effects multivariable time-to-event models (survival analysis) for each of the 6 procedures to model surgical case duration.

RESULTS:
We identified performance outliers, based on surgical case duration, using 2013 data and then quantified the gap between high- and low-performance outliers using 2014 data. After adjusting for patient risk, patients undergoing surgery at high-performance facilities were between 54% and 79% more likely to exit the operating room (OR) per unit time compared to average-performing facilities, depending on the procedure. For example, patients undergoing a laparoscopic appendectomy at high-performance facilities were 68% more likely to exit the OR per unit time (hazard ratio, 1.68; 95% CI, 1.40–2.02; P < .001) compared to average-performing facilities. Patients undergoing a laparoscopic appendectomy at low-performance facilities were 41% less likely to exit the OR per unit time (hazard ratio, 0.59; 95% CI, 0.47–0.74; P < .001) compared to average-performing facilities. The adjusted median surgical case duration for patients undergoing laparoscopic appendectomy was 69 minutes at high-performance centers and 92 minutes at low-performance centers. Similar results were obtained for the other procedures.

CONCLUSIONS:
There was wide variation in surgery case duration for patients undergoing common general surgical and orthopedic surgeries. This variability in care delivery may represent an important opportunity to promote more efficient use of health care resources.
Delirium: reducing risks and improving quality of life
Authors: Nazarko Linda 
Published: March 2018

Edith Watson seemed to be having an ordinary day when she loaded her groceries into the boot of her car, but then she fell and fractured her wrist. Three weeks later, staff on the ward she was admitted to told her horrified daughter that it was clear Mrs Watson couldn't cope at home and it might be best if she found a nursing home for her mother. In three short weeks, Mrs Watson had gone from a woman who was able to drive, manage her home and was fully independent to a confused, immobile old lady who was at risk of falls. Sometimes, confusion is overlooked or not considered abnormal in older people. The Royal College of Physicians (2017) has just amended the National Early Warning Score (NEWS) and new confusion is now identified and is to be escalated to doctors or nurse practitioners, so that it will no longer be possible to overlook this important sign of distress. This article explores how healthcare can harm as well as heal and how understanding of the risks of hospitalisation can enable people to retain ability and confidence in hospital.
Research roundup: March 2018
Authors: Som Rita 
Published: March 2018

In brief Study shows that tiotropium has the potential to reduce asthma exacerbation risk in the under 5s Retrospective audit of prescribing activity in an acute hospital offers a meaningful way to elucidate prescribing trends and practices, and direct CPD for prescriber's critical care outreach team Pressure ulcer risk assessment instrument found to be suitable for use in clinical practice Study finds no association between antidepressants and epithelial ovarian cancer risk
Interfacial Transition Zone of Cement Composites with Recycled Concrete Aggregate of Different Moisture States
Authors: Brand Alexander S. , Roesler Jeffery 
Published: March 2018

Abstract
Past research suggests that the moisture state of recycled concrete aggregate (RCA) at the time of concrete mixing can dramatically affect the concrete properties. This study employed image analysis of backscattered electron micrographs to monitor the interfacial transition zone (ITZ) development in coarse mortars with a highly absorptive RCA at oven dry (OD), saturated surface dry (SSD), and sub-SSD (i.e., 80 % SSD) moisture conditions. The batching water was not adjusted to account for the aggregate moisture condition to explicitly evaluate the effect of the RCA moisture condition. The 28-day compressive strength was found to be greatest for the sub-SSD RCA mix, followed by the OD RCA and SSD RCA mixes. No difference was found in the ITZ microstructure between mixtures with sub-SSD and SSD RCA. The OD RCA appreciably affected the ITZ by demanding water, which reduced the local water-to-cement ratio, yielded an increase in the unhydrated (UH) cement content, reduced the bulk microstructure porosity, and increased the estimated ITZ size. Because these ITZ trends do not directly correlate with the compressive strength trends, it is postulated that the sub-SSD will absorb some of the cement slurry during mixing, allowing for a stronger interfacial mechanical bond to form. This does not occur to the same extent for the SSD RCA, but will likely also occur for the OD RCA; however, the OD RCA absorbs so much water that it deters hydration, yielding a larger ITZ with a higher UH content, so the bulk strength of the mortar with OD RCA is less than that of mortar with sub-SSD RCA.
Performance, Combustion and Emission Characteristics of CI Engine Fueled with Sweet Lime Peel Oil (Citrus Limetta)
Authors: Logesh G. , Madhavan Venkataramanan 
Published: March 2018

Abstract
Fuels derived from biomass waste are of great interest because of their availability and renewable potential. Also, the depletion of fossil fuels and the subsequent search for new alternative fuels opened up a new arena of biomass research. Sweet lime oil (SLO), which is a waste biomass left from sweet lime fruit peel (Citrus limetta) contains flammable oil. The present work focuses on testing and promoting SLO as an alternative fuel in a diesel engine. Extracted SLO is blended with diesel in various proportions; the various test fuels used are a blend of 10 % SLO with 90 % neat diesel (denoted as SLO10), a blend of 20 % SLO with 80 % neat diesel (SLO20), a blend of 40 % SLO with 60 % neat diesel (SLO40), and 100 % SLO (SLO100). Experiments were conducted using a single-cylinder, constant speed, direct injection diesel engine at different load conditions. Outcomes were compared to conventional diesel fuel throughout the load. The results indicate that SLO100 has better results than the other test blends, with 33 % brake thermal efficiency. SLO diesel blends exhibited lower carbon monoxide and hydrocarbon emissions with comparatively higher carbon dioxide emissions with respect to neat diesel fuel. Oxides of nitrogen are higher for all SLO blends, especially SLO100, compared to neat diesel. The peak cylinder pressure for SLO100 and the peak heat-release rate for SLO10 is greater than that of other test fuels. It was concluded that SLO100 can be used in a direct injection diesel engine without any engine modifications.
Energy-Based Forming Mechanism and Criterion for Zonal Disintegration
Authors: Chen Xuguang , Zhang Ning , Zhang Mingsheng , Niu Xiaodong , Li Yanlong 
Published: March 2018

Abstract
The law of energy dissipation and release during rock damage is studied, and the energy-based criterion for rock damage is obtained. Based on these findings, the mechanism and criterion for zonal disintegration are studied. An equivalent excavation model is proposed to obtain the releasable energy during the rock mass excavation. This releasable energy distribution in rock mass shows the elastoplastic boundary fractured with the release of the conserved energy. The zonal disintegration is thus revealed to be the circulation of this fracture along with the constant formation of the new elastoplastic boundary. Meanwhile, a sliding fracture model in polar coordinates is proposed, and the dissipated energy is calculated for the circle fracture formation. Consequently, the criterion for Zonal Disintegration Phenomenon (ZDP) is constructed according to the energy conservation law. Additionally, a formula is inferred through the criterion to determine the numbers of disintegration zones. This energy-based theory is verified as effective by applying it to an actual deep cavern where ZDP occurs.
HUBUNGAN ANTARA GAYA ATRIBUSI DENGAN TINGKAT PRESTASI AKADEMIK
Authors: Marliani Rosleny 
Published: March 2018

The goal of this research is to find the crucial factors that influence the level of adolescence’s academic achievement. The objective of this research is to study the relationship between adolescence’s attributional style with their level of academic achievement. This research was carried out by correlational design. This research involve adolescence as students of three public senior high school in Bandung City, i.e. SMAN 4, SMAN 8, and SMAN 11. The sample of this study are 459 students selected through random from second and third grade. The students at first grade not selected as sample because them not yet owned the data of achievement. The data of achievement was collected by documentation study, and data of attribution by questionnaire. The data expressed in ordinal scale and analyzed statistically by Rank Spearman. This study has some outcomes related to the relationship between style of attribution with academic achievement. Students which attributing their academic success with high ability and effort or working hard and attributed their academic failure with lack of effort and luck, tend to attain high achievement. While the students that attributing their academic success with easy task and luck, and attributed their academic failure with lack of ability and difficult task, tend to attain low achievement. Based on the findings, to increasing the level of student’s academic achievement can be conducted by train the students to developing the adaptive attribution style, that is to attributing their success academic with ability and effort factors, and to attributing their failure academic with lack of effort an luck.
POLA PENGASUHAN DEMOKRATIS ORANG TUA DAN GAYA KEPEMIMPINAN DEMOKRATIS GURU SEBAGAI PREDIKTOR KECERDASAN EMOSIONAL SISWA
Authors: Saman Abdul 
Published: March 2018

The objective of the study was to assess (1) descriptive about the students’ emotional intelligence, their perception towards democratic parenting model and the teacher’s democratic leadership style; (2) the correlation between the democratic parenting model with the emotional intelligence; (3) the teachers’ democratic leadership style with emotional intelligence, and 4) the correlation between the democratic parenting model and the teachers’ democratic leadership style with the emotional intelligence. The sample consisted of 182 student of SMA Negeri 2 Watampone, academic year 2007-2008, selected bay way of proporsional random sampling. The questionnaires to collect the data was designed to assess the perception about the democratic parenting by parents, the teachers’ democratic leadership style, and the emotional intelligence. The data were analyzed by employing the Simple Regression analysis technique for hypotesis one and two, and Multiple Regression for hypotesis three. The results of the correlation indicated (1) there was a significant correlation between emotional intelligence with the perception of democratic parenting model, (2) the emotional intelligence is significantly correlated with the perception obout the teacers’ democratic leadership style and (3) there was a significant correlation between the perception obout the democratic parenting model and the perception obout the teachers’ democratic leadership style with emotional intelligence. The two predictors provided an effective contribution at 46 percent against the variation of criteria emotional intelligence.
STIMULASI TUMBUH KEMBANG ANAK
Authors: Yenawati Sri 
Published: March 2018

Children, like adults are also have their own problems in life. Nowadays, we also know that lacks of self confidence not just for adult only, children are also have the same problem. It is also encouraged by their undeveloped ability both mentally and physically. Independency is also one of many problems that must be faced by children especially children with mental disorder or mental retardation. This phenomena then become a basis for this research—that is emphasizes on children development stimulation. It was also considered that pre-natal condition is also has influence over children’s development after they born. This paper is then pre-describe developmental stage of children at their golden age, with developmental tasks and crisis that come along within every stages. Stimulation to encourage children’s development would also be discussed in this paper with hopes that many people could then take any profit from this paper and optimizing their effort in raising and teaching their children.
PENGARUH KOMITMEN KARIR DAN KESUKSESAN KARIR SUBJEKTIF TERHADAP KESIAPAN MENGHADAPI PERUBAHAN
Authors: Fridayanti Fridayanti 
Published: March 2018

The aim of this study is to test the influence of career commitment and subjective career success toward readiness to change. The subject of this study were 41 full time teachers who work in SMA ,which is hold the status of Pioneering International Standard-Based School and now this school is being process of change to become International Standard Based Schol. Data was collected by three measuring instruments or questionaires, namely by career commitment, subjective career success and readiness for change. Measurements were conducted using path analysis, with the assistence by software Statistical Packages for Social Science (SPSS) 17.0 for Windows. The result of this research showed that hypothesis to be tested was significan,. It means that readiness to change could be predicted by career commitment and subjective career succes, either simultaneously or partially. The amount of power influence of career commitment is 24.76 % (0.2476). Subjective Career Success toward readiness to change is 16,61% (0,166). Simultaneously, the amount of influence of career commitment and subjective career success toward readiness to change is 41,4% (0,144)
MENGHINDARKAN REMAJA DARI PENYALAHGUNAAN NARKOBA MELALUI INTERVENSI IDENTITAS
Authors: Yuliati Nanik 
Published: March 2018

This paper intended to give a conceptual framework in order to prevent adolescent from drug abuse by using a developmental approach. Search for identity is one aspect of psychosocial development which very crucial in periods of adolescence and most developmentalist which agree that healthy or unhealthy personality developmental be attributable to the process of search for identity. Most developmentalist have a belief that adolescents achieve a sense of identity tend to demonstrate a healthy and constructive behavior, while failing achieve becoming vulnerable to various forms of psychosocial disturbance, one of which drug abuse. Therefor, to prevent teenagers from drug abuse we can do with helping them to achieve a sense of identity.