bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rendre l’objet pénétrable. Discussion du texte de Marilia Aisenstein
Authors: Miller Patrick 
Published: December 2018

La notion de relation allergique définie par P. Marty implique des mouvements de régression du psychique au physiologique, en particulier une proximité des réactions de défense dans l’ordre immunologique et psychique. Chez ces sujets la prématurité d’une interprétation en termes de séparation / individuation peut avoir des effets catastro­phiques. Avant de parvenir à ce degré de l’interprétation l’analyste doit pouvoir accepter de faire l’expérience avec son patient de moments d’interpénétration psychique souvent accompagnés d’une dimension corporelle. La disposition à la pénétrabilité psychique chez l’analyste peut favoriser chez le patient la découverte d’une capacité à pénétrer l’objet. Rendre l’objet pénétrable est pour P. Marty un aspect important de l’aménagement de l’objet.
Le labyrinthe de la culture
Authors: Bachler Laurent 
Published: December 2018

Comment notre culture, ou les différentes cultures auxquelles nous appartenons, contribuent-elles à forger notre identité ? L’association de ces deux termes, identité et culture, ne va pas de soi : l’identité est stable et fixe ; la culture est mouvante et sans cesse en mouvement. Dès lors, si la culture nous dit quelque chose de notre identité, c’est qu’elle est changeante, complexe et parfois même faite de contradictions. Il ne s’agit pas de gommer ces contradictions, mais d’essayer, au contraire, d’en faire une force et une ressource pour être vraiment nous-mêmes.
Les spécificités du maternage des bébés au Vietnam… selon la tradition, et leurs évolutions aujourd’hui
Authors: Hoffet-Gachelin Marie-Ève 
Published: December 2018

La spécificité du maternage au Vietnam se repère dans l’attention apportée à la construction du sentiment de sécurité du bébé et à l’importance de l’éducation : dès qu’il commence à parler, on lui apprend les liens de parenté entre les membres de la famille et les adresses. C’est une façon de donner sa place à l’enfant, inscrite dans la hiérarchie familiale. Cette éducation se maintient encore actuellement alors que les pratiques de maternage se modifient. Nous citons entre autres le rapport à la nourriture : une contrainte très forte est introduite dans le nourrissage, les famines antérieures ayant laissé de fortes traces. L’éducation précoce est une contrainte supplémentaire. Elle laisse peu de place au jeu et à la créativité, ce qui complique le rapport des jeunes avec la modernité.
Transcription Factor STAT3 Serves as a Negative Regulator Controlling IgE Class Switching in Mice
Authors: Dascani Paul , Ding Chuanlin , Kong Xiangyu , Tieri David , Hu Xiaoling , Zhang Huang-ge , Kitamura Daisuke , Bolli Roberto , Rouchka Eric C , Yan Jun 
Published: December 2018

Abstract
A mutation in STAT3 has been linked to the incidence of autosomal dominant hyper IgE syndrome, a disease characterized by elevated serum IgE Ab. However, how this genetic mutation leads to the phenotype has not been fully understood. We investigated the specific role of STAT3 in the germinal center (GC) B cells and plasma cells for IgE class switching. Through the use of STAT3 conditional knockout (cKO) mice in a Th2-type immunization model, we demonstrated that CD2-Cre–driven STAT3 cKO mice showed elevated IgE and decreased IgG1 in the serum and a reduction in GC formation. Within the GC, IgG1+ GC B cells were decreased, whereas IgE+ GC B cells were more prevalent. Additionally, these mice exhibited reduced IgG1 and elevated IgE populations of Ab-producing plasma cells. Subsequent experiments using a CD19-Cre cKO mouse established this effect to be B cell–intrinsic. Transcription factors critical for GC and plasma cell differentiation, including Bcl-6 and Aicda, were shown to function as downstream signals of STAT3 regulation. Chromatin immunoprecipitation sequencing analysis revealed that many genes, including Bcl3 and Crtc2, were among the direct STAT3 regulated targets. Mice with STAT3 deficiency in B cells also demonstrated an increase in lung inflammation when used in an asthma-like disease model. This model suggests a negative role for STAT3 in regulating class switching of the GC B cells from the IgG1 to the IgE producing state, which may serve as a therapeutic target for treatment of autosomal dominant hyper IgE syndrome and other immune disorders.
Predictive Factors of Treatment Outcomes for Hospital Care in Children with Acute Methadone Poisoning
Authors: Atighi Yasamin , Eizadi-Mood Nastaran , Mansourian Marjan , Zamani Amin , Saffaei Ali , Sabzghabaee Ali Mohammad 
Published: December 2018

Objective:
The trend of methadone toxicity in children and adolescents seems to be increasing in Iran since it is used as a legal measure of the treatment for opioids addiction in methadone maintenance therapy clinics. In the present study, we describe the clinical and demographical characteristics of acute methadone toxicity in a cohort of pediatric poisoned patients in Isfahan, Iran and discussed the predictive factors for their treatment outcomes.

Methods:
In this 4-year cross-sectional study which was performed from 2013 to 2016 in a referral university hospital (Isfahan, Iran), medical records of the demographic and admission time clinical characteristics of all in-patients aged <18 years with acute methadone poisoning were abstracted and analyzed. According to the outcomes of hospital care and treatment, patients were divided as survived without medical complication and patients survived with at least one medical complication or death.

Findings:
A total number of 157 (79 male) children and adolescents with a mean age of 105.4 ± 6.1 months were hospitalized and included in the study. A total of 145 (92.4%) patients survived and discharged from the hospital without any medical complication. Pupil size, respiratory rate, and level of consciousness were predictive factors for the outcome of death or medical complications.

Conclusion:
It seems that methadone poisoning in children and adolescents is more commonly accidental in school-aged boys (6–12 years old) and it occurs mostly with the syrup dosage form, especially when one of the parents or people who live with the child has an addiction history and if the patients' house located in lower socioeconomic class area of Isfahan city (Iran).
Off-Label Prescribing of Antipsychotics in a Danish Child and Adolescent Mental Health Center
Authors: Kornø Kristine Tøfting , Aagaard Lise 
Published: December 2018

Objective:
We analyzed prescribing patterns of antipsychotics for children and adolescent affiliated with a Danish Child and Adolescent Mental Health Center) with respect to age, sex, medicine, diagnoses, off-label status, and time.

Methods:
We included all patients below 19 years of age prescribed antipsychotics during 2007–2008 and as of November 1, 2014. Prescription data included all antipsychotic prescriptions and prescriptions of concomitant psychotropic medications. We defined an antipsychotic user as a patient receiving at least one prescription during the study period, irrespective of any previous history of antipsychotic use. We defined off-label prescribing as prescriptions outside the licensed age group and approved indication.

Findings:
We analyzed 404 antipsychotic prescriptions that were located for 150 patients. The patients were between 7 and 18 years of age. Two-thirds of the prescriptions were for girls and two-thirds of prescriptions for olanzapine and quetiapine. Totally, 92% of all prescribed antipsychotics were used off-label. For typical antipsychotics, this share was 96% and for atypical antipsychotics 90%. As of November 1, 2014, the total share of off-label antipsychotic prescriptions was 96%, and 63% of these were for medications prescribed outside the approved age group, and 26% for nonlicensed indication(s).

Conclusion:
This study demonstrated a high level of off-label prescribing over time with respect to age and indication. The prescribing patterns underpin the need for further economic incentives for pharmaceutical companies to register pediatric indications, particular for off-patent products.
Obmejna območja in narodnostne manjšine na Madžarskem leta 1990
Authors: Toth Jozsef 
Published: December 2018

Analiza narodnostne sestave obmejnih območij Madžarske temelji na popisnih podatkih iz leta 1990 in prikazuje Slovake, Romune, Hrvate, Srbe, Slovence in Nemce.
Geografija in etnologija na mladinskih raziskovalnih taborih v Beli Krajini
Authors: Dular Andrej 
Published: December 2018

Želja po čim večjem spoznavanju in uveljavljanju humanističnih in družboslovnih znanstvenih disciplin med mladimi je privedla do organiziranja posebnih oblik mladinskega raziskovalnega dela - do mladinskih raziskovalnih taborov. Njihov namen je seznaniti zainteresirane učence višjih razredov osnovnih šol in dijake s posamičnimi strokami, predmetom in metodami raziskav kakor tudi s cilji strokovnega prizadevanja, to je z njihovo uporabnostjo. Pri tem gre zlasti za praktično terensko in kabinetno delo, ki ga dijaki opravljajo pod vodstvom mentorjev, temelječe na sodobnih metodoloških in metodičnih principih, pa tudi na novih pogledih na predmet raziskovanja.
Japage: udornice na Kupreškem polju, Bosna in Hercegovina
Authors: Stepišnik Uroš 
Published: December 2018

Kupreško polje se nahaja na dinarskem krasu v zahodni Bosni in Hercegovini. V bližini severovzhodnega roba polja leži skupina udornic, ki se imenujejo japage. Rezultati raziskave so pokazali, da je razporeditev te skupine udornic pogojena s kamninsko sestavo, ki je vplivala na razvoj jamskega sistema, ki spodkopava material pod udornicami. Prisotnost spodkopavanja in prav tako površinske rečne akumulacije sta bistveno vplivala na oblikovanost dnov udornic.
Regionalni razvoj v SR Sloveniji
Authors: Vrišer Igor 
Published: December 2018

Razprava poskuša s pomočjo devetih kazalcev, ki podajajo razvitost proizvajalnih sil, učinke delovanja proizvajalnih sil in razvitost družbenega standarda, pokazati spreminjanje stopnje regionalne razvitosti v 12 regijah Slovenije v obdobju 1952-1982.
Prostorski vidiki ponudbe in povpraševanja po novih telekomunikacijskih uslugah v ZR Nemčiji
Authors: Kordey Norbert 
Published: December 2018

Hiter razvoj telekomunikacijske tehnologije pogojuje tudi njihovo neomejeno uporabnost, ki se v ZR Nemčiji hitro širi. V uporabi prednjačijo gospodarsko razvita območja, potencialna pa so zlasti območja suburbanizacije. Avtor prikazuje regionalno razporeditev uporabnikov telekomunikacijskih uslug.
Analiza mestne morfologije - dve metodi vrednotenja uličnih pročelij, predstavljeni na primeru mestnega središča Frankfurta na Maini
Authors: Bross Michael 
Published: December 2018

Prikazani metodi temeljita na fiziognomski, arhitekturni, socialni in organizacijski analizi. Predvsem naj bi sintetsko in kvantitativno predstavili najbolj identičen geografski aspekt mestne zgradbe.
Koncept endogenega regionalnega razvoja turizma v obrobnih območjih - primeri iz Frankovskega sredogorja
Authors: Troeger Weiss Gaby 
Published: December 2018

Prikazani so prostorski elementi turistične infrastrukture z vsemi spremljajočimi problemi, ki zavirajo hitrejši razvoj turizma. Podani so predlogi za ukrepe v zvezi s tem.
Sodobni načini geografskega proučevanja značilnosti prometnih omrežij
Authors: Černe Andrej 
Published: December 2018

Članek prikazuje nekatere elemente teorije grafov, kot primer sodobnega geografskega načina proučevanja prometa in prometnega omrežja, ki omogočajo kvantitativno analizo in vrednotenje povezanosti in dostopnosti krajev v prometnem omrežju, hkrati pa tudi proučevanje značilnosti prometa in prometnega omrežja v razmerju do ostalih geografskih značilnosti pokrajine.
Savremeni problemi domačeg i inostranog turizma u Jugoslaviji
Authors: Stanković Stevan M. 
Published: December 2018

Turizam u Jugoslaviji ima dugu i bogatu tradiciju. Domači turizam ima nekoliko osnovnih karakteristika. Analiza jc pokazala da su neke od njih identične sa stranim turizmom. To znači da obe vrste turizma treba sinhronizovano razvijati.
Primer uporabe GIS pri iskanju možnih virov onesnaževanja vode na krasu
Authors: Krevs Marko , Jurinčič Igor 
Published: December 2018

Geografske informacijske sisteme lahko koristno uporabimo tudi na delovnih področjih, kjer nimamo na razpolago vseh ustreznih podatkov, metod za njihovo vrednotenje ter modeliranje. Takšen primer je tudi pomoč GIS pri iskanju možnih virov onesnaževanja na krasu. Razen redkih površinskih vodotokov (na fluviokrasu) se tam vode pretakajo po podzemlju. Zato moramo prisotnost krasa v zaledju površinskega vodotoka obravnavati na "poseben" način, pri čemer nam je GIS v veliko pomoč. GIS je v tem primeru dejansko podpora deduktivncmu pristopu k obravnavi problema. Z upoštevanjem "kraških predpostavk" glede možnega pretakanja podzemskih voda se območje možnih virov onesnaževanja znatno razširi preko meja površinskega porečja. Na podlagi vrednotenja upoštevanih predpostavk, podatkovnih slojev in njihovih medsebojnih relacij sva ločila tri "območja ogrožanja kvalitete vode" Otavščice. Ta lahko služijo za načrtovanje in izvajanje nadaljnjih ukrepov za rešitev problema. Izvajanje aplikacije na prenosnem osebnem računalniku omogoča njeno uporabo pri terenskih meritvah ter pri terenskem iskanju in popisovanju dejanskih virov onesnaževanja. V obravnavo je vključeno 255 kvadratnih kilometrov veliko območje jugozahodnega obrobja Ljubljanskega Barja (širša okolica porečja Otavščice, pritoka Borovniščice).
Sistem ARCGIS
Authors: Šuntar Aleš 
Published: December 2018

Opisan je praktični primer delovanja geografskega informacijskega sistema - sistem ARCGIS. Sistem ARCGIS predstavlja zametek GlS-a, ki naj bi preizkusil primernost podatkov, testiral strokovne in informacijske standarde ter opozoril na probleme, ki bodo nastali ob uvajanju GlS-tehnologije v naš prostor. Pri izgradnji sistema ARCGIS se je pokazala vsa širina in kompleksnost problematike uvajanja GlS-tehnologije v neko okolje. Pri razvoju sistema in njegovem uvajanju v prakso smo se povezali z zunanjimi sodelavci ter vzpostavili stike s številnimi strokovnjaki različnih strok.
Geodetski podatki za geografske informacijske sisteme
Authors: Lipej Božena 
Published: December 2018

Prispevek obravnava v prvem delu nekatere pristope pri vzpostavljanju večnamenskih podatkovnih baz v geodeziji, v drugem pa praktično izkušnjo avtoric pri pripravi podatkov za vnos v geografske informacijske sisteme (GIS) z orodjem editor.
Utilização da metodologia WebQuest nas aulas de matemática: uma proposta para o estudo de matrizes
Authors: Faligurski Fim Camila , Ceolin Pinto Pâmela , Luvezute Kripka Rosana Maria 
Published: December 2018

Apresenta-se resultados de uma pesquisa em desenvolvimento, na qual se propõe a utilização do recurso tecnológico digital da WebQuest para o ensino e a aprendizagem de matemática. Também propõe-se a elaboração de uma tarefa para abordagem do tópico matrizes, envolvendo o uso de materiais educacionais, disponibilizados na rede mundial de computadores (WWW), bem como o uso da resolução de problemas, tendo em vista potencializar e facilitar a aprendizagem significativa desse objeto matemático. Pretende-se aplicar a tarefa com estudantes do ensino médio, com o objetivo de avaliar qualitativamente as implicações observadas em termos de aprendizagens ocorridas.
Explosion Math: um jogo digital como recurso na aprendizagem de Matemática
Authors: Takita Bruna , Santana Jackson , De Souza Pedro 
Published: December 2018

Este artigo tem como objetivo apresentar o desenvolvimento e a aplicação de um jogo digital educacional que aborda conteúdos específicos da Matemática dos anos finais do ensino fundamental I, com foco no 5º ano. Explosion Math, inspirado no jogo clássico Bomberman, foi desenvolvido utilizando o motor gráfico Unity 3D e pretende auxiliar o ensino de matemática de forma diferenciada e dinâmica. O jogo propõe aos alunos uma viagem com o astronauta Albert, um garoto apaixonado por Matemática, que, ao descobrir a existência de planetas matemáticos, embarca em uma aventura espacial. A missão de Albert é explorar os planetas Numérico, Geométrico e Grammy (grandezas e medidas), a fim de obter o conhecimento presente em cada um deles.
Pensamento computacional na educação básica: interface tecnológica na construção de competências do século XXI
Authors: Conforto Debora , Cavedini Patrícia , Miranda Roxane , Caetano Saulo 
Published: December 2018

Este artigo discute a implementação da ação pedagógica Oficina de Pensamento Computacional no âmbito da educação básica, em Porto Alegre, objetivando socializar uma das possíveis respostas para o desafio de alinhar a escola às demandas colocadas por um contexto sociocultural, político e econômico edificado pelas tecnologias da informação e comunicação. Problematizam-se as premissas que justificam a inclusão dessa ação na grade curricular, delineando as estratégias de implementação, de acompanhamento e de avaliação, especialmente por escutar os participantes e dar voz a eles.
Nova abordagem para a estimativa do fluxo de calor no solo para o Bioma Pampa
Authors: Romio Leugim Corteze , Zimmer Tamíres , Roberti Débora Regina , Buligon Lidiane 
Published: December 2018

The study of the thermal properties of the soil and the variables dependent on these properties is very important for the understanding of the surface energy balance. Among the main variables, there is the soil heat flux, especially because it allows the verification of the influences that occur in the biome of a region as temperature variation occurs. This work intend to estimate the coefficient of thermal conductivity and, thus, to obtain the values for the soil heat flux. The data used to estimate the parameters were obtained from an experimental site located in the city of Pedras Altas-RS. Two equations were used, the first one defined by the Fourier Heat Conduction Law (discretized) and the second one a modification of the first one including a k coefficient, named “modeling error”. Based on the results obtained it can be verified that the modified equation presented better results, when compared with the classical solution.
Comparação entre dois modelos de função footprint aplicados ao sítio experimental de Pedras Altas
Authors: Bremm Tiago , Toro Ivan Mauricio Cely , Veeck Gustavo Pujol , Roberti Débora Regina , Buligon Lidiane 
Published: December 2018

Micrometeorological towers are installed in several regions in order to collect atmospheric data at high frequency for the estimation of micrometeorological parameters and surface flows of energy and mass. The determination of the towers field of view and, therefore, the flow measured at the sensors is defined by the footprint, which is directly influenced by the geometry of the terrain and by the vegetation of the site on which the sensor is installed. In this way, the present work aims to analyze the predominant area of the flow contribution by two different methods of footprint determination: one analytical model and one lagrangian stochastic. The data were analyzed for the micrometeorological station of Pedras Altas, located in the south western region of Rio Grande do Sul. The results show that the stochastic model considers the tower field of view closer than the analytical model, consequently it covers a smaller area.
Perfis verticais dos espectros das velocidades turbulentas em uma torre micrometeorológica de 140 m
Authors: Acevedo Otávio Costa , Oliveira Pablo Eli Soares de , Teichrieb Claudio Alberto , Puhales Franciano Scremin , Martins Luis Gustavo Nogueira , Degrazia Gervásio Annes , Silva Samuel Martins , Maroneze Rafael 
Published: December 2018

Multiresolution spectra of both horizontal and vertical wind components observed at a 140-m micrometeorological tower are analysed. The tower is located at the township of Linhares, ES, Brazil, at 4 km from the coast and nest to a thermal power plant. At nighttime, the spectral maximum is located at the largest temporal scales analyzed, being therefore related to nonturbulent low-frequency processes. During the day, spectral maxima of the horizontal wind components show little variation above 20 m.For the vertical component, on the other hand, the temporal scale of such maxima increases steadily with height.
Too Much Academic Research Is Being Published
Authors: Altbach Philip G. , De Wit Hans 
Published: December 2018

There is a crisis in academic publishing and in the global knowledge-distribution system in general—there is too much pressure on top journals, there are too many books and articles of marginal quality, predatory journals are on the rise, and there is a tremendous pressure on academics worldwide to publish. We propose recognizing that most universities and most academics, globally, focus on teaching, and that the large majority of universities acknowledge their important roles as teaching-focused and do not seek to become research-intensive institutions. We call for quality, but also for control of what quality is, by the academic community instead of by nonacademic rankers, publishers, and citation and impact measurers. Quality—not quantity—should be the objective, in combination with an effort to bring quality control back into the academic community—while making sure that that control is not dominated by small groups in research universities in the rich countries.
Arkeologiske undersøkelser ved Láksjohka, Tana kommune, Finnmark 2004
Authors: Skandfer Marianne 
Published: December 2018

Archaeological field report (in Norwegian) from registration and test-pitting at Láksjohka, Deatnu/Tana municipality, Finnmark. Includes background, methods, observations and AMS-dates. Illustrated.Report from the same site 2006: http://doi.org/10.7557/7.4313Report from the same site 2007: http://doi.org/10.7557/7.4334
Arkeologiske undersøkelser på Kjerringneset, Sør-Varanger kommune, Finnmark 2004
Authors: Skandfer Marianne 
Published: December 2018

Excavation report in Norwegian. Investigations of two lage, rectangular house-pits. Both had hearth-areas along the long mid-axis similar to so-called "Gressbakken houses". Radiocarbon dates from different layers in the hearths showed re-use: dates fall into the second millennium BC and around BC/AD. Under the wall in one of the houses were older flakes and tool fragments, belonging to an older settlement phase. It cannot be said if this was related to a house structure.Related publication:Skandfer, M. 2012. " Change and Recollection: House Structures and Social Identification in Finnmark, Artic Norway 2400 BC - AD 300." In Damm, Charlotte and Saarikiivi, Janne (eds.): Networks, Interaction and Emerging Identities in Fennoscandia and Beyond. Papers from the Conference held in Tromsø, Norway, October 13-16 2009. Suomalais-Ugrilainen Seura / Finno-Ugrian Society 2012 pp. 155-176 (2017-06-12)Related reports:http://doi.org/10.7557/7.4314http://doi.org/10.7557/7.4312http://doi.org/10.7557/7.4313http://doi.org/10.7557/7.4334http://doi.org/10.7557/7.4333
Rapport fra utgravning: "Fosslund" (g.nr. 16/1), Sør-Varanger k., Finnmark
Authors: Skandfer Marianne 
Published: December 2018

Excavation report. Excavation of house-pit at "Fosslund" in Pasvik River Valley 2000, as part of PhD project. Trench through wall and floor, uncovering a fire-pit with clay (some possibly from vessels) and burnt bones and quartz. Some quartz scrapers and flakes in floor area. Radiocarbon dated to 405–205 BC and 200–35 BC.Related publication:Skandfer, M. 2012. " Change and Recollection: House Structures and Social Identification in Finnmark, Artic Norway 2400 BC - AD 300." In Damm, Charlotte and Saarikiivi, Janne (eds.): Networks, Interaction and Emerging Identities in Fennoscandia and Beyond. Papers from the Conference held in Tromsø, Norway, October 13-16 2009. Suomalais-Ugrilainen Seura / Finno-Ugrian Society 2012 pp. 155-176 (2017-06-12)Related reports:http://doi.org/10.7557/7.4334http://doi.org/10.7557/7.4311http://doi.org/10.7557/7.4314http://doi.org/10.7557/7.4313