bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors, Incidence, and Outcomes of Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation Complicated by Stroke
Authors: Vlastra Wieneke , Jimenez-Quevedo Pilar , Tchétché Didier , Chandrasekhar Jaya , de Brito Fabio S. , Barbanti Marco , Kornowski Ran , Latib Azeem , D’Onofrio Augusto , Ribichini Flavio , Baan Jan , Tijssen Jan G.P. , De la Torre Hernandez Jose M. , Dumonteil Nicolas , Sarmento-Leite Rogério , Sartori Samantha , Rosato S. , Tarantini Giuseppe , Lunardi Mattia , Orvin Katia , Pagnesi Matteo , Hernandez-Antolin Rosana , Modine Thomas , Dangas George , Mehran Roxana , Piek Jan J. , Delewi Ronak 
Published: March 2019

Background:
Stroke remains one of the most devastating complications of transcatheter aortic valve implantation (TAVI). The aim of this study was to identify the incidence, timing, temporal trends, and predictors of stroke after TAVI and evaluate the outcomes of patients with stroke.

Methods and Results:

The CENTER-Collaboration is an international collaboration consisting of 3 national registries and 7 local registries or prospective clinical trials, selected through a systematic review. Accordingly, a total of 10 982 patients undergoing transfemoral TAVI between 2007 and 2018 were included in the current patient-level pooled analyses. A total of 261 patients (2.4%) experienced stroke during the first month after TAVI. The median time between TAVI and stroke was 1 day (interquartile range, 0–6 days). The stroke rate was comparable in procedures performed in the early years of TAVI (2007–2012) to those in the more recent years of TAVI (2013–2018; both 2.4%;
P
=1.0). Independent predictors of stroke at 30 days were a history of cerebrovascular events (odds ratio, 2.2; 95% CI, 1.4–3.6;
P
=0.0012) and a glomerular filtration rate of <30 mL/min per 1.73 m
2
(odds ratio, 1.7; 95% CI, 1.0–2.8;
P
=0.05). Stroke occurring within the first 30 days after TAVI was associated with a 6-fold increase of 30-day mortality (odds ratio, 6.0; 95% CI, 4.4–8.1;
P
<0.001). Moreover, patients with stroke more frequently had documented new-onset atrial fibrillation (16% versus 3%;
P
<0.001) and major or life-threatening bleedings (12% versus 7%;
P
=0.002) at 30-day follow-up.

Conclusions:
In this large, global, patient-level analysis, the incidence of stroke after transfemoral TAVI was 2.4%. Prior cerebrovascular events and a low glomerular filtration rate independently predicted the occurrence of stroke after TAVI. The occurrence of stroke after TAVI was associated with a strikingly 6-fold increase of 30-day mortality; additionally, there was a 5-fold higher rate of new-onset atrial fibrillation in patients with stroke.

Clinical Trial Registration:

URL:
https://www.clinicaltrials.gov
. Unique identifier: NCT03588247.
Quality of Life Changes After Chronic Total Occlusion Angioplasty in Patients With Baseline Refractory Angina
Authors: Hirai Taishi , Grantham J. Aaron , Sapontis James , Cohen David J. , Marso Steven P. , Lombardi William , Karmpaliotis Dimitri , Moses Jeffrey , Nicholson William J. , Pershad Ashish , Wyman R. Michael , Spaedy Anthony , Cook Stephen , Doshi Parag , Federici Robert , Nugent Karen , Gosch Kensey L. , Spertus John A. , Salisbury Adam C. ,   on behalf of the OPEN-CTO Study Group
Published: March 2019

Background:
Health status and quality of life improvement after chronic total occlusion (CTO) percutaneous coronary intervention (PCI) among patients with refractory angina has not been reported. We sought to determine the degree of quality of life improvement after CTO PCI in patients with refractory angina.

Methods and Results:

Among 1000 consecutive patients who underwent CTO PCI in a 12-center registry, refractory angina was defined as any angina (baseline Seattle Angina Questionnaire [SAQ] Angina Frequency score of ≤90) despite treatment with ≥3 antianginal medications. Health status at baseline and 1-year follow-up was quantified using the SAQ. Refractory angina was present at baseline in 148 patients (14.8%). Technical success was achieved in 120 (81.1%) at the initial attempt and major adverse cardiac and cerebral events occurred in 10 (6.8%). There were no procedural deaths. Refractory angina patients were highly symptomatic at baseline with mean SAQ Angina Frequency of 51.1±23.8, SAQ quality of life of 35.3±21.2, and SAQ Summary Score of 47.2±17.9, improving by 32.0±27.8, 35.7±23.9, and 32.1±20.1 at 1 year. Through 1-year follow-up, patients with successful CTO PCI had significantly larger degree of improvement of SAQ Angina Frequency and SAQ Summary Score (35.0±26.8 versus 18.8±28.9,
P
<0.01; 34.2±19.4 versus 22.5±20.8,
P
<0.01) compared with unsuccessful CTO PCI.

Conclusions:
Refractory angina was present in 1 of 7 patients in the OPEN-CTO (Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion Hybrid Procedures) registry. Patients with refractory angina experienced large, clinically significant health status improvements that persisted through 12 months, and patients with successful CTO PCI had larger health status improvement than those without.
High‐Sensitivity Cardiac Troponin After Cardiac Stress Test: A Systematic Review and Meta‐Analysis
Authors: Samaha Eslam , Avila Audrey , Helwani Mohammad A. , Ben Abdallah Arbi , Jaffe Allan S. , Scott Mitchell G. , Nagele Peter 
Published: March 2019

Background
The recent introduction of high‐sensitivity cardiac troponin (hs‐cTn) assays has allowed clinicians to measure hs‐cTn before and after cardiac stress testing, but the hs‐cTn release pattern and potential utility in identifying inducible myocardial ischemia are unclear. We thus conducted a systematic review and meta‐analysis to improve our understanding of hs‐cTn release associated with exercise and pharmacological stress testing.

Methods and Results

Studies published between January 2008 and July 2016 that reported hs‐cTn change values (high‐sensitivity cardiac troponin T [hs‐cTnT] or high‐sensitivity cardiac troponin I [hs‐cTnI]) in relation to cardiac stress testing were searched and reviewed by 2 independent screeners. Primary outcomes were pooled estimates of absolute and relative hs‐cTn changes after cardiac stress test, stratified by the presence of inducible myocardial ischemia. This meta‐analysis included 11 studies (n=2432 patients). After exercise stress testing, hs‐cTnT increased by 0.5 ng/L or 11% (6 studies, n=406) and hs‐cTnI by 2.4 ng/L or 41% (4 studies, n=365) in patients with inducible myocardial ischemia versus hs‐cTnT by 1.1 ng/L or 18% (8 studies, n=629;
P
=0.29) and hs‐cTnI by 1.8 ng/L or 72% (4 studies, n=831;
P
=0.61) in patients who did not develop inducible myocardial ischemia. After pharmacological stress test, hs‐cTnT changed by −0.1 ng/L or −0.4% (6 studies, n=251) and hs‐cTnI by 2.4 ng/L or 32% (2 studies, n=108) in patients with inducible myocardial ischemia versus hs‐cTnT by 0.7 ng/L or 11% (5 studies, n=443,
P
=0.44) and hs‐cTnI by 1.7 ng/L or 38% (2 studies, n=116;
P
=0.62) in patients who did not develop inducible myocardial ischemia.

Conclusions
hs‐cTn rising patterns after exercise and pharmacological stress testing appear inconsistent and comparably small, and do not appear to be correlated with inducible myocardial ischemia.
Breastfeeding and Cardiovascular Disease Hospitalization and Mortality in Parous Women: Evidence From a Large Australian Cohort Study
Authors: Nguyen Binh , Gale Joanne , Nassar Natasha , Bauman Adrian , Joshy Grace , Ding Ding 
Published: March 2019

Background

Few studies have investigated the longitudinal association between breastfeeding and maternal cardiovascular disease (
CVD
) outcomes. This study examined the association between breastfeeding and
CVD
hospitalization and mortality in a large Australian cohort.

Methods and Results

Baseline questionnaire data (2006–2009) from a sample of 100 864 parous women aged ≥45 years from New South Wales, Australia, were linked to hospitalization and death data until June 2014 and December 2013, respectively. Analysis was restricted to women without self‐reported medically diagnosed
CVD
at baseline or without past
CVD
hospitalization 6 years before study entry. Never versus ever breastfeeding and average breastfeeding duration per child, derived from self‐reported lifetime breastfeeding duration and number of children, and categorized as never breastfed, <6, >6 to 12, or >12 months/child, were assessed. Cox proportional hazards models were used to explore the association between breastfeeding and
CVD
outcomes. Covariates included sociodemographic characteristics, lifestyle risk factors, and medical and reproductive history. There were 3428 (3.4%) first
CVD
‐related hospital admissions and 418 (0.4%) deaths during a mean follow‐up time of 6.1 years for
CVD
hospitalization and 5.7 years for
CVD
mortality. Ever breastfeeding was associated with lower risk of
CVD
hospitalization (adjusted hazard ratio [95% CI]: 0.86 [0.78, 0.96];
P
=0.005) and
CVD
mortality (adjusted hazard ratio [95% CI]: 0.66 [0.49, 0.89];
P
=0.006) compared with never breastfeeding. Breastfeeding ≤12 months/child was significantly associated with lower risk of
CVD
hospitalization.

Conclusions

Breastfeeding is associated with lower maternal risk of
CVD
hospitalization and mortality in middle‐aged and older Australian women. Breastfeeding may offer long‐term maternal cardiovascular health benefits.
Changes in Childhood Body‐Mass Index and Risk of Venous Thromboembolism in Adulthood
Authors: Sundbøll Jens , Ängquist Lars , Adelborg Kasper , Gjærde Line Klingen , Ording Anne , Sørensen Thorkild I. A. , Baker Jennifer L. , Sørensen Henrik Toft 
Published: March 2019

Background

Childhood weight trajectories may influence cardiometabolic traits and thereby the risk of venous thromboembolism (
VTE
) later in life. We examined whether overweight and changes in weight status during childhood were associated with risk of
VTE
in adulthood.

Methods and Results

We used Danish medical registries to conduct a population‐based cohort study of Danish schoolchildren aged 7 to 13 years and born during 1930‐1989. We calculated body‐mass index (
BMI
) z‐scores based on weight and height measurements. We estimated hazard ratios using Cox regressions to examine associations between changes in
BMI
z‐scores from 7 to 13 years of age and the subsequent risk of
VTE
. Among 313 998 children, 5007 girls and 5397 boys were diagnosed with
VTE
as adults. Compared with children with a normal
BMI
(25th to 75th percentile category) at both ages, children with a
BMI
persistently above the 75th percentile had a 1.30‐ to 1.50‐fold increased risk of
VTE
in adulthood. Children who experienced a
BMI
increase from the 25th to 75th or >75th to 90th percentile to a higher percentile category had a 1.35‐ to 1.70‐fold increased risk of adulthood
VTE
. Children whose
BMI
percentile category decreased between 7 and 13 years of age had a
VTE
risk similar to that of children with a persistently normal
BMI
.

Conclusions

Risk of
VTE
in adulthood was higher in children with a persistently above‐average
BMI
. Whereas weight gain from 7 to 13 years of age additionally increased
VTE
risk, remission from overweight by 13 years of age completely reverted the risk.
FİNANSMAN SAĞLAMADA MUDARABE SUKUK VE MÜŞAREKE SUKUKUN ORTAKLIĞA DAYALI KİRA SERTİFİKALARI BOYUTUYLA DEĞERLENDİRİLMESİ VE MUHASEBELEŞTİRİLMESİ
Authors: Çelenk Hakan , Çebi Asım 
Published: March 2019

Sukuk, küresel sermaye
piyasasında yeni bir gelişmeyi temsil etmektedir. Son yıllarda islami finansal
enstürümanlardan sukukta bir artış yaşandı. Bu, islami finansın büyümesi için
büyük bir potansiyel sunmaktadır. Hızla büyüyen tüm İslami sermaye piyasası menkul
kıymetlerinin hiçbiri sukuk kadar popüler değildir. İslami sermayenin ülkemize
çekilmesi gerçekten önemli hale gelmiştir. Ayrıca ülkemiz içindeki faize karşı
duyarlı yatırımcılarında bu alan üzerinden ekonomiye kazandırılmaları
gerekmektedir. Faizsiz finans sektöründe ortaya çıkan ve “faizsiz bono” olarak
tanımlanan sukuk ülkemizde “kira sertifikası” adıyla düzenlenmiştir. Bu sebeple ülkemizde sukuk uygulamalarını
artırmak amacıyla çeşitli düzenlemeler yapılmaktadır. Özellikle bu çalışmada
ülkemiz açısından müşareke sukuk ve müdarebe sukukun işleyişi,
değerlendirilmesi ve muhasebeleştirilmesi ele alınmaktadır.
Racial Discrimination
Authors: Hernández Tanya Katerí 
Published: March 2019

Abstract
This fifth volume in the Brill Research Perspectives in Comparative Discrimination Law surveys the field of comparative race discrimination law for the purpose of providing an introduction to the nature of comparing systems of discrimination and the transnational search for effective equality laws and policies. This volume includes the perspectives of racialized subjects (subalterns) in the examination of the reach of the laws on the ground. It engages a variety of legal and social science resources in order to compare systems across a number of contexts (such as the United States, Canada, France, South Africa, Brazil, Colombia, Peru, Hong Kong, Japan, Korea, Israel, India, and others). The goal is to analyze the strengths and weaknesses of various kinds of anti-discrimination legal devices to aid in the study of law reform efforts across the globe centered on racial equality.
A new species of Ponthieva (Cranichidinae, Orchidaceae) from Bolivia
Authors: KOLANOWSKA MARTA , BARANOW PRZEMYSŁAW , FUENTES ALFREDO F. 
Published: March 2019

A new species of Ponthieva, P. boliviensis, is described and illustrated based on Bolivian material. The novelty resembles P. pilosissima and P. hermiliae characterized by pilose leaves and free lateral sepals. From P. pilosissima the new species differs in the shallowly concave lip, ovate-triangular basal lip auricles which are more or less parallel to the claw and ovate lip disc. Unlike in P. boliviensis, the lip of P. hermiliae is yellowish-green to greenish-white, lanceolate-triangular, lacking basal lobes, concave on the proximal half, with a 6-toothed callus placed horizontally in front of the basal cavity.
Five new species of Macrostomus Wiedemann and a checklist of Empididae (s. str.) (Diptera) from Bolivia
Authors: RAFAEL JOSÉ ALBERTINO , MARQUES DAYSE WILLKENIA ALMEIDA 
Published: March 2019

Ten Bolivian species of Macrostomus Wiedemann were studied. Five species are redescribed based on type specimens described by Bezzi. The species are included in the following species-groups: four in the M. ferrugineus species-group: M. arcucinctus (Bezzi), M. argyrotarsis (Bezzi), M. dolichopterus (Bezzi) and M. grallatrix (Bezzi); three in the M. limbipennis species-group: M. macerrimus (Bezzi), M. montanus sp. nov. and M. rodriguezi sp. nov.; one species in the M. amazonensis species-group: M. falcatus sp. nov.; and two unplaced to species-group: M. trifidus sp. nov. and M. trilineatus sp. nov. A key to the 12 species of Macrostomus found in Bolivia, including M. limbipennis (Bezzi) and M. pictipennis (Bezzi), is presented. Macrostomus argyrotarsis (Bezzi) is also recorded for the first time from Peru. A checklist of 31 described species of Bolivian Empididae s. str. is included. Three empidid species originally described from Mexico that had previously been recorded from Bolivia, are excluded from the Bolivian fauna.
Comments on “A Wave-Resolving Simulation of Langmuir Circulations with a Nonhydrostatic Free-Surface Model: Comparison with Craik–Leibovich Theory and an Alternative Eulerian View of the Driving Mechanism”
Authors: Mellor George 
Published: March 2019

AbstractThe results of the subject paper are reviewed wherein credible Langmuir cells are produced by a numerical solution of the primitive fluid dynamic equations with a free surface. Whereas it is a major achievement, the claim that the same results support the general application of the so-called vortex force equations is challenged.
Ecological Interface Design: Thirty-Plus Years of Refinement, Progress, and Potential
Authors: Bennett Kevin B. , Flach John 
Published: March 2019

Objective: The objective is to provide a review of ecological interface design (EID), to illustrate its value to human factors/ergonomics, and to identify areas for future research and development. Background: EID uses mature interface technologies to provide decision making and problem solving support. A variety of theoretical concepts and analytical tools have been developed to meet the associated challenges. EID provides support that is simultaneously grounded in the practical realities of a work domain and tailored to human capabilities and limitations. Method: EID’s theoretical foundation is discussed briefly. Concrete examples of ecological and traditional interfaces are provided. Different categories of work domains are described, as well as the associated implications for interface design. A targeted literature review is conducted and the experimental outcomes are summarized. A representative evaluation is discussed, and interpretations of performance are provided. Results: The evidence reveals that EID has been remarkably successful in significantly improving performance for work domains with constraints that are law driven (e.g., process control). In contrast, work domains that are intent-driven (e.g., information retrieval) have, by and large, been ignored. Also, few studies have addressed nonvisual displays. Conclusion: EID has not yet realized its potential to improve safety and efficiency across the entire continuum of work domains. Application: EID provides a single integrated framework that is (a) sufficiently comprehensive to deal with complicated work domains and (b) capable of producing innovative support that will generalize to actual work settings.
A turning point for labour market policy in Australia
Authors: Stanford Jim 
Published: March 2019

Australian labour market and industrial relations policies are poised for fundamental change. A combination of political and macroeconomic factors has created a historic opportunity to turn away from the individualised, market-driven labour market policy that has prevailed since the 1980s, in favour of a more interventionist and egalitarian approach. Factors contributing to this moment include the breakdown of bipartisan consensus around key neoliberal precepts; growing public anger over inequality, insecure work and stagnant wages; and a weakening of macroeconomic conditions. Australia’s labour market is now marked by underutilisation of labour in various forms, a deterioration in job quality (especially the growth of insecure and precarious work) and unprecedented weakness in wages. The deterioration in job quality and distributional outcomes is the long-term legacy of the post-1980s shift away from Australia’s earlier tradition of equality-seeking institutional structures and regulatory practices. The current malaise in labour markets should be confronted with a comprehensive strategy to both increase the quantity of work available to Australian workers and improve its quality. The major components of such a strategy are identified, and their prospects considered, in light of the economic and political forces reshaping Australia’s labour market. JEL Codes: J28, J38, J53, J58, J83
Critical Literacy in the Post-Truth Media Landscape
Authors: Barton Colin C 
Published: March 2019

In the post-truth era, information is harder to trust than ever before. News has become more about entertainment than information and consumers now subscribe to media in order to have their view reinforced and not challenged. The media environment has become more tribal, defining the people who consume it. On top of this environment, the plague that is fake news has descended upon the internet, making truth a relative concept rather than a scientific one. Navigating the media and finding truth in current events has become a confusing process. In the wake of the major events of 2016 – Brexit and the United States election, two events that were defined by misinformation, lies and fake news – post-truth emerged as a political term to define the era we now live in. It is one where truth is of little value and people give in to the politics of emotion rather than fact. This sets a dangerous scene for democracy and threatens to undermine any major future democratic processes. In order to alleviate this issue, a critical media literacy must be adopted in education. Students need to be given the tools to critically analyse media as well as understand the structures of power behind media organizations, what their goals are and who they serve. In doing so, fake news can lose much of its power and truth can emerge.
Demonstration of a Fair Level of Agreement Between Escalation Scores Reported by Hospital Managers and Analysis of Stress-Related Hospital Metrics
Authors: van Woerden Hugo C. , Walker Neil J. , Kiparoglou Vasiliki , Yang Yaling 
Published: March 2019

Background: The National Health System in Wales has developed a novel national electronic dashboard which reports a daily “escalation score,” reflecting management’s opinion of the pressure each hospital is facing, primarily due to unscheduled care. The aim of this study was to examine the possibility of replacing human scores with a quantitative model, based on the relationship between reported escalation scores and selected hospital metrics. Methods: Generalized linear mixed models were used to model the association between hospital metrics and escalation scores between October one year and October the next year utilizing hospital bed occupancy rate, ambulance hours lost waiting outside emergency departments, number of “boarded out” patients in the hospital, and the daily ratio of admissions to discharges in the hospital. These models were tested against a subsequent period (December unto May the following year), using three models: “general,” “hospital-specific,” and “group-specific.” The model generated by the initial time frame was tested against data from the subsequent time frame using weighted κ. Results: Across 16 hospitals, using 3343 escalation scores, the rates of agreement and weighted κ were: general model (48.8%; 0.16), hospital-specific model (45.0%; 0.25), and group-specific model (43.1%; 0.25). A 17th small hospital was excluded due to missing data. Conclusions: This is novel research as no similar studies were identified, although the topic is important as it addresses a major current health-care challenge. Automated scores can be derived which have the advantage of being derived objectively, avoiding human inter- and intraindividual variation. Prospective testing is recommended to assess potential service planning benefit.