bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of Quercetin Loaded Microparticles and their Antitumor Activity against Human Lung Cancer Cells (A549) in vitro
Authors: Li Chen , Gao Liufang , Zhang Yi , Simpson Benjamin K. 
Published: July 2019

Background:
Novel quercetin-loaded microparticles (QM) were fabricated using coaxial
electrospraying, characterized for surface morphology and release profile, and evaluated for antitumor
activity in vitro.

Methods:
QM exhibited an average diameter of 1.69 ±1.13 mm, which was an appropriate size suitable
for respiratory delivery. X-ray diffraction patterns showed that the components in QM existed in an
amorphous physical form, leading to favorable interactions between the drug (quercetin), the polymer
matrix (polyvinylpyrrolidone, PVP) and other excipients (sodium dodecyl sulfate and sucralose).

Results:
QM performed much faster release rate compared with free quercetin powder (Q) in vitro.
Furthermore, QM also showed more potent inhibitory effects on A549 cell growth with reduced cell
viability, decreased cell migration and induced more G0/G1 phase cell cycle arrest than Q.

Conclusion:
Thus, the quercetin loaded microparticles exhibited more potent inhibitory effects than
free quercetin on A549 cell. The increased antitumor activity could be attributed to the enhanced
accumulation of quercetin in the A549 cells with the QM. However, further studies are necessary to
elucidate the exact mechanisms.
Evaluation of TG-HDL Ratio Instead of HOMA Ratio as Insulin Resistance Marker in Overweight and Children with Obesity
Authors: Behiry Eman G. , El Nady Nazih Mohamed , AbdEl Haie Omima M. , Mattar May Kamel , Magdy Amira 
Published: July 2019

Background:
Homeostasis model assessment for insulin resistance (HOMA-IR) is widely
used as a marker of insulin resistance in adults and has also been validated in children and adolescents.
Triglyceride (TG) and HDL-C on the other hand is a routine test and inexpensive compared to insulin.
Previous studies reported conflicting findings on the usefulness of the triglyceride to HDL-C ratio
(TG:HDL-C ratio) as predictor or marker of IR. The aim of this work was to investigate the usefulness
of Triglyceride to HDL-C ratio (TG/HDL-C) as an Insulin Resistance (IR) marker in overweight and
children with obesity.

Methods:
This study was a comparative cross sectional study which was conducted on ninety overweight
and children with obesity attending National Nutrition Institute “Pediatric obesity clinic. They
were classified into 2 groups as follows: group (1) included overweight and children with obesity with
insulin resistance, group (2) included overweight and children with obesity with non-insulin resistance.
All the subjects were subjected to history, clinical examination and laboratory investigations including
total lipid profile, fasting glucose, insulin and TG:HDL-C ratio instead of HOMA ratio.

Results:
Prevalence of IR among the studied sample was 42 (46.7%). Mean value of TG/ HDL-C ratio
was greater among the insulin resistance group than non insulin resistance group (p value= <
0.001)value). TG/HDL ratio ≥1.36 had 85.7% sensitivity, 66.7% specificity. There was statistically
significant positive correlation between TG/HDL ratio and HOMA-IR.

Conclusion:
TG:HDL ratio ≥1.36 is a significant early and sensitive predictor of insulin resistance in
children instead of HOMA-IR.
Pengembangan model aquarobic exercise untuk pembakaran lemak pada overweight
Authors: Sanusi Rahmat , Widiyanto Widiyanto 
Published: July 2019

Penelitian ini bertujuan menghasilkan model latihan alternatif yang layak untuk pembakaran lemak dan sebagai latihan non-traumatic untuk orang dengan overweight. Penelitian ini merupakan penelitian pengembangan (research and development) yang mengacu pada langkah yang dikembangkan Borg & Gall melalui tahapan: pengembangan draf awal, model awal, model, uji coba produk, evaluasi dan revisi. Subjek uji coba terbatas sebanyak 3 orang dan subjek uji coba lapangan sebanyak 6 orang dengan kriteria mengalami masalah kelebihan berat badan (overweight). Pengumpulan data melalui uji pelaksanaan, penilaian ahli dengan lembar kuisioner, tes pengukuran denyut nadi dan pengukuran penurunan persentase lemak. Teknik analisis data menggunakan analisis deskriptif. Hasil penelitian menunjukkan bahwa model aquarobic exercise untuk pembakaran lemak ditinjau dari bentuk, isi dan tujuan latihan oleh ahli kebugaran jasmani, ahli fisiologi dan ahli renang dikategorikan “Baik”. Hasil data pre dan post test menujukkan peningkatan nilai rata-rata denyut nadi dan penurunan persentase lemak. Disimpulkan bahwa model aquarobic exercise layak dan efektif untuk pembakaran lemak pada overweight. Developing aquarobic exercise model for fat burn in overweight AbstractThis research aim to development a alternative model for fat burn This model can and as non-traumatic exercise to people with overweight. This research is the development (research and development) which refer from Borg & Gall prosedur was done through stage developing preliminary model, developing model, trials of product, evaluation and revision. Limited scale trials was conducted on 3 women and large scale trials was conducted on 6 womens. The instrumen used to collect data were implementation test, assessment from expert with quisioner sheet, heart rate and estimate fat percentage. Analysis techniques in this research used descriptive statistic. The results of the research show that aquarobic exercise model review from the form, content and purpose the exercise from expert assessment by physical fitnees expert, fisiologi expert and swiming expert are “good”. The result of pre and post test show there is an increase mean score heart rate and decrease fat percentage. So, it can be conclude that the aquarobic exercise modelis suitable and effetive for fat burner in overweight.
Pengembangan aplikasi tes keterampilan sepakbola berbasis web
Authors: Supriyono Eko 
Published: July 2019

Penelitian bertujuan untuk menghasilkan produk Aplikasi Tes Keterampilan Sepakbola (Soccer Skill Test) Berbasis Web dan buku panduan. Penelitian ini merupakan penelitian pengembangan, melalui 5 tahapan, yaitu: (1) studi pendahuluan dan pengumpulan informasi, (2) desain produk awal, (3) validasi ahli/revisi, (4) ujicoba lapangan skala kecil/revisi, (5) uji coba skala besar dan produk akhir. Subjek penelitian adalah ahli materi, ahli media, dan pelatih Sekolah Sepakbola di Daerah Istimewa Yogyakarta. Instrumen berupa angket dan observasi. Hasil penelitian yaitu Aplikasi Tes Keterampilan Sepakbola (Soccer Skill Test) Berbasis Web yang berisi menu pokok yaitu: (1) Menu Home, (2) Menu Panduan Tes dan Konversi Hasil Tes Keterampilan Sepakbola yang bisa di input secara individu maupun data Excel, (3) Aplikasi tes terdiri dari 7 item tes keterampilan sepakbola yaitu: tes dribbling, passing-control, shooting, passing lambung, juggilng, heading, (4) Menu contak admin. Developing web-based soccer skills test application AbstractThis research aimed to produce web-based soccer skills test application. This research belonged to research and development with model of procedural descriptive that outlined the steps which should be followed to create a product. The development of web-based soccer skills test application were done in 5 steps, namely: (1) undertaking pre-study and information collection, (2) developing design of initial product, (3) expert validation and revision, (4) small-scale field test and product revision, (5) large-scale field test and final product. The subjects of this research and development were material expert, media expert and coaches of soccer school of Yogyakarta Province (DIY). The instrument of this research were questionnaire and observation. The result of this research was a web-based soccer skills test application was produced that contained main menu, namely: (1) Home, (2) menu of test guide and the conversion of result of soccer skill test which could be inputted individually or by Excel data, (3) the test application consisted of 7 items of soccer skills, that were: test of dribbling, passing-control, shooting, long-passing, juggling, heading, (4) menu of administrator’s contact.
Karakteristik psikologis atlet Sea Games Indonesia ditinjau dari jenis cabang olahraga dan jenis kelamin
Authors: Nopiyanto Yahya Eko , Dimyati Dimyati 
Published: July 2019

Penelitian ini bertujuan untuk mengungkapkan: (1) karakteristik psikologis atlet SEA Games Indonesia ditinjau dari cabang olahraga individu, (2) ditinjau dari cabang olahraga tim, (3) perbedaan karakteristik psikologis atlet SEA Games Indonesia ditinjau dari cabang olahraga individu berdasarkan jenis kelamin, dan (4) olahraga tim berdasarkan jenis kelamin. Pendekatan penelitian ini adalah ex-post facto. Penelitian ini merupakan penelitian populasi. Semua subjek dalam populasi diikutsertakan dalam penelitian dengan jumlah 273 atlet. Pengumpulan data menggunakan kuesioner The Psychological Skills Inventory for Sports. Teknik analisis data menggunakan independent sample t-test. Hasil penelitian ini menunjukkan bahwa: (1) karakteristik psikologis atlet SEA Games Indonesia ditinjau dari cabang olahraga individu dalam kategori tinggi (2) ditinjau dari cabang olahraga tim dalam kategori tinggi (3) tidak ada perbedaan yang signifikan karakteristik psikologis atlet SEA Games Indonesia ditinjau dari cabang olahraga individu berdasarkan jenis kelamin dengan nilai sig. = 0,092 > 0,05; dan (4) ada perbedaan yang signifikan karakteristik psikologis atlet SEA Games Indonesia ditinjau dari cabang olahraga tim berdasarkan jenis kelamin dengan nilai nilai sig. = 0,000 < 0,05. The psychological characteristics of Indonesian Sea Games athletes in terms of sports and sex AbstractThis research was aimed to investigate : (1) the psychological characteristics of Indonesian SEA Games athletes in terms of individual sports, (2) in terms of team sports, (3) the psychological characteristic differences of Indonesian SEA Games athletes in terms of individual sports based on sex, and (4) the psychological characteristic differences of Indonesian SEA Games athletes in terms of team sports based on sex. This research employed the quantitative approach using the survey method with a restrospective causal-comparative design. This research was population research. All subjects in the population were included in this research with a total of 273 athletes. The data were collected using the Psychological Skills Inventory for Sports questionnaire and analyzed using the independent sample t test at. The research findings revealed that: (1) the psychological characteristics of Indonesian SEA Games athletes in terms of individual sports were in a high category, (2) the psychological characteristics of Indonesian SEA Games athletes in terms of team sports are in high category, (3) there were no significant differences in the psychological characteristics of Indonesian SEA Games athletes in terms of individual sports based on sex sig. values = 0.092 > 0.05, and (4) there were significant differences in the psychological characteristics of Indonesian SEA Games athletes in terms of team sports based on sex with sig. values = 0.000 < 0.05.
Persepsi mahasiswa Fakultas Ilmu Keolahragaan Universitas Negeri Yogyakarta terhadap atribut produk minuman kesehatan
Authors: Vidya Chairina , Nisa Fatma Zuhrotun , Palupi Ika Ratna 
Published: July 2019

Pemberian cairan sangat penting bagi atlet untuk menghindari dehidrasi yang dapat menyebabkan gangguan fisiologis tubuh. Produk minuman kesehatan diyakini mampu meningkatkan energi dan menjaga produktivitas pada saat dan setelah melakukan aktivitas fisik seperti bekerja dan olahraga, terutama bagi para olahragawan. Perilaku membeli produk minuman kesehatan dilakukan berdasarkan preferensi dan kebutuhan konsumen, salah satunya mempertimbangkan atribut produk. Penelitian ini bertujuan untuk mengetahui persepsi mahasiswa Fakultas Ilmu Keolahragaan Universitas Negeri Yogyakarta (FIK UNY) terhadap atribut produk minuman kesehatan (harga, kemasan, merek, label, dan rasa). Penelitian menggunakan desain observasional cross sectional dengan subjek penelitian 100 orang mahasiswa FIK UNY yang diambil secara purposif. Analisis data menggunakan statistik deskriptif. Hasil penelitian menunjukkan bahwa sebagian besar subjek memiliki persepsi positif terhadap atribut produk minuman kesehatan. Kemasan yang mudah dibawa dan dipegang serta informasi nilai gizi merupakan indikator yang dianggap paling penting oleh subjek. Perception on healthy drink product attributes among sports sciences college students in Universitas Negeri Yogyakarta AbstractIntake of fluids is very important for athletes to avoid dehydration which can cause physiological disorders of the body. Health drink products are supposed to increase energy and maintain productivity during and after physical activities such as work and exercise, especially for athletes. The behavior of buying health drink products is based on consumer preferences and needs, one of them considering product attributes. This study aimed to determine perception of students of the Faculty of Sport Sciences Yogyakarta State University (FIK UNY) on the attributes of health drink products (price, packaging, brand, label, and taste). The research used observational cross-sectional design. Subjects were 100 students of FIK UNY selected through purposive sampling. Data analysis employed descriptive statistics. The results showed that most respondents had positive perceptions on health drink product attributes. Packaging that was easy to carry and hold as well as information of nutritional value was an indicator that was considered most important by the subjects.
Pengembangan perlindungan sosial kampung ramah anak di Kota Yogyakarta
Authors: Suharta Robertus Belarminus , Septiarti Serafin Wisni 
Published: July 2019

Artikel ini bertujuan menjelaskan tentang Kampung Ramah Anak sebagai program perlindungan sosial yang dapat berkembang melalui pendekatan budaya dilaksanakan di Kelurahan Tegalejo Yogyakarta. Penelitian dengan metode kualitatif dengan FGD, observasi dan wawancara mendalam sebagai teknik pengumpulan datanya. Data dianalisis secara deskriptif untuk diintepretasi kebermaknaannya. Hasil penelitian menunjukkan bahwa perlindungan sosial melalui program KRA merupakan konsep yang dibangun pemerintah Kota Yogyakarta untuk memenuhi hak hidup, belajar, perlindungan dan partisipasi anak dalam pembangunan. Secara kultur, masyarakat menanggapinya dengan prinsip kebersamaan, komitmen, mengintegrasikan makna ramah anak dalam bentuk berbagai kegiatan yang melibatkan orang tua, anak muda dan tokoh masyarakat. KRA dikembangkan melalui (1) mengucapkan deklarasi kawasan tanpa rokok dalam setiap pertemuan pengurus RW; (2) membangun keakraban orang tua-anak seperti kerjasama, persatuan, toleransi yang dibingkai dalam kegiatan yang inovatif, edukatif, menyenangkan seperti outbond, gerak tari dan seni tradisional.Development of child friendly social protection in Yogyakarta City AbstractThis article aims to explain about Child Friendly Village (KRS) as a social protection program that can develop through cultural approach implemented in Tegalejo Village Yogyakarta. Research with qualitative method with FGD, observation and in-depth interview as data collection technique. The data were analyzed descriptively to interpret their meaningfulness. The results showed that social protection through the KRA program is a concept developed by the Yogyakarta city government to fulfill the right to live, learn, protect and participate in development. Culturally, the community responds with the principle of togetherness, commitment, integrating the meaning of child-friendly in the form of various activities involving parents, young people and community leaders. KRA is developed through (1) declaring a non-smoking area declaration in every RW committee meeting; (2) establishing parent-child familiarity such as cooperation, unity, tolerance that is framed in innovative, educational, fun activities such as outbound, dance movements and traditional arts.
Pemberdayaan wanita tani melalui produksi abon ikan lele
Authors: Harianti Rini , Tanberika Fajar Sari 
Published: July 2019

Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan ibu-ibu melalui pelatihan dan pendampingan dalam pengelolaan abon ikan lele dan menciptakan peluang usaha secara nyata di masa mendatang. Pelaksanaan kegiatan dimulai dengan pengadaan alat. Metode yang digunakan adalah training of trainer (TOT), yaitu pemberian materi melalui ceramah, praktek langsung, dan pendampingan. Pemberdayaan ini telah mampu menghasilkan 3 varian rasa abon ikan lele (manis, asin dan pedas). Hasil organoleptik menunjukkan bahwa abon lele dengan rasa manis adalah yang terbaik. Abon lele terpilih memiliki kadar air 7,71%, abu 4,59%, protein 26,50%, lemak 24,12%, dan negatif dari mikroba Salmonella. Produk abon lele telah memperoleh lisensi P-IRT, berlabel dan berstandar halal. Kegiatan ini sangat bermanfaat dalam meningkatkan pengetahuan dan keterampilan ibu-ibu, sehingga perlu dilakukan inovasi lebih lanjut dalam pengolahan abon lele agar produk yang dihasilkan dapat memiliki kualitas yang lebih baik. Empowerment of farmers through the production of shredded catfish AbstractThis activity aimed to improve the knowledge and skills of mothers through training and mentoring in the management of shredded catfish and create real business opportunities in the future. The activity starts with the procurement of tools. The method used was trained of trainers (TOT), namely the provision of materials through discourse, direct practice, and mentoring. This empowerment had to produce 3 flavors of shredded catfish (sweet, salty and spicy). The organoleptic results showed that shredded catfish with sweet flavors was best. The shredded catfish selected had 7.71% moisture content, 4.59% ash, 26.50% protein, 24.12% fat, and negative from Salmonella microbes. The shredded catfish products have obtained P-IRT license, has labeled and halal standards. This activity is very useful in increasing the knowledge and skills of mothers, so that further innovation needs to be carried out in the processing of shredded catfish so that the products produced can be of better quality.
Peran perempuan dan penduduk terdidik dalam upaya mencapai target sustainable development goals di Indonesia
Authors: Widiastuty Isti Larasati 
Published: July 2019

Penelitian ini bertujuan untuk mengetahui perkembangan ketenagakerjaan di Indonesia, peran perempuan dan penduduk terdidik dalam pencapaian target Sustainable Development Goals (SDGs) di Indonesia. Mencapai tujuan SDGs memerlukan partisipasi, kerja dan sinergitas yang komprehensif dari berbagai pihak. Penelitian ini ingin menyoroti bagaimana mencapai target kedelapan SDGs dengan memperhatian peran perempuan dalam pembangunan dan aktivitas kerja. Metode analisis yang digunakan adalah analisis dekriptif dan analisis statistik regresi linier berganda. Sumber data yang digunakan berasal dari Badan Pusat Statistik (BPS). Beberapa indikator ketenagakerjaan menunjukkan tren meningkat dari 2010 - 2018. Penduduk terdidik mendominasi kegiatan bekerja dan penganggur di Indonesia. Pada tahun 2018 jumlah penganggur terdidik sebanyak 65,89% dari total penganggur. Variabel yang mempengaruhinya adalah rata-rata upah, tingkat kemiskinan, tingkat kesempatan kerja terdidik, jumlah penduduk miskin dan jumlah penduduk usia kerja, dengan koefisien determinasi 0,959. Partisipasi perempuan dalam aktivitas kerja dan sumbangan pendapatannya dalam ekonomi lebih rendah daripada laki-laki, namun secara tren menunjukkan peningkatan. The role women and educated population in effort to achieve sustainable development goals in Indonesia AbstractThis study aims to determine the development of employment in Indonesia, the role of women and educated residents in achieving the targets of Sustainable development Goals (SDGs) in Indonesia. Achieving the goals s of SDGs requires comprehensive participation, work and synergy from stakeholders. This study wants to highlinght how to reach the eighth target of SDGs bay paying attention to the role of women in development and work activities. The analytical method used descriptive analysis and statistical analysis of multiple linier regression. The data source used is secondary data from Statistics Indonesia (BPS). During this period several employment indicators showed an increasing trend each year. Educated population dominates work activities and unemploment people in Indonesia. In 2018 the number of educated unemployment reached 65,89% of the total unemployed people in Indonesia. The variables that influence it are average wages, poverty levels, educated employent rates, the number of poor people and the number of working-age population, with a coefficient of determination arround 0.959. women’s participation in work activities and the contribution of their income in the economy is lower than men, but in trend shows an increase.
Penyuluhan kesehatan terhadap masyarakat: Perawatan penderita asam urat dengan media audiovisual
Authors: Simamora Roymond Hamonangan , Saragih Ellyanor 
Published: July 2019

Tujuan dari kegiatan ini untuk meningkatkan pengetahuan masyarakat dalam penatalaksanaan perawatan penderita asam urat di lingkungan XIV Kelurahan Sunggal yang merupakan Wilayah Desa Binaan Fakultas Keperawatan Universitas Sumatera Utara. Metode kegiatan penyuluhan dilakukan selama 4 hari, dengan metode ceramah dengan menggunakan media audiovisual. Jumlah responden sebanyak 60 orang. Hasil kegiatan: Diperoleh peningkatan pengetahuan masyarakatdari 5% menjadi 88,3% menjadi kategori baik. Dari hasil kegiatan ini menunjukkan adanya manfaat penyuluhan masyarakat dengan menggunakan media audiovisual terhadappengetahuan masyarakat. Penggunaan media audiovisual menyuguhkan gambar dan suara, sehingga pesan penyuluhan dapat lebih mudah dipahami oleh masyarakat, dan media ini dapat disajikan berulang ulang dengan memutar kembali materi penyuluhan melaluihandphone peserta penyuluhan, media penyuluhan kesehatan dengan audiovisual dianggap efektif dan dapat dijadikan sebagai pilihan media dalam penyuluhan kesehatan bagi masyarakat. Public health counseling: Management of care for gout patients using audiovisual media AbstractThe purpose of this activity is to increase public knowledge in the management of care for gout sufferers in the XIV neighborhood of Sunggal Village, which is a development village village of the Faculty of Nursing, University of North Sumatra. The extension activity method is carried out for 4 days, with the lecture method using audiovisual media. The number of respondents is 60 people. Results of the activity: Increased community knowledge from 5% to 88.3% into good categories. From the results of this activity, it shows the benefits of community education by using audiovisual media on people's knowledge. The use of audiovisual media presents images and sounds, so that the counseling message can be more easily understood by the public, and this media can be presented repeatedly by replaying counseling material through mobile education participants, health education media with audiovisuals are considered effective and can be used as media choices in health education for the community.