bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Anneroth’s Scoring and Frequency of Cervical Lymph Node Metastasis among Primary Oral Squamous Cell Carcinoma Patients
Authors: Haque Mohammad Ahtashamul , Goswami Uday Kumar , Rahman Md Mostafijur , Islam Mohammad Wahidul , Morshed Md Mahboob , Islam Md Rafiqul , Azam Md Bakhtiar 
Published: September 2019

Background: Primary Oral Squamous Cell Carcinoma can metastasize in the cervical lymph nodes.
Objective: The purpose of the present study was to see the association of Anneroth’s scoring and frequency of cervical lymph node metastasis among primary oral squamous cell carcinoma patients.
Methodology: This cross sectional study was conducted in the Department of Oral and Maxillofacial Surgery, Dhaka Dental College and Hospital, Dhaka, Bangladesh from November 2009 to December 2010 for a period of one year. Patients attending in the place of study with diagnosed case of oral squamous cell carcinoma were selected for the study after fulfilling the inclusion criteria. The resected primary lesion and neck lymph nodes were sent for histopathological examination. Histopathological grading of the primary lesion was done and neck lymphodes were graded as metastatic and non-metastatic.
Results: This prospective study with 50 cases of oral squamous cell carcinoma was taken of which 28 cases were non-metastasis tumor. Each case was graded according to TNM classification, Broder’s grading and Anneroth’s classification. Both Anneroth’s classification (p=0.002) and Broder’s grading (p=0.017) were significant but Anneroth’s one was more significant than Broder’s.
Conclusions: There is an association between Anneroth’s grading system with lymph node metastasis.
Journal of Current and Advance Medical Research 2019;6(2): 69-72
Clinico-Demographic Characteristics and Surgical Outcomes of Thyroid Swelling Patient Attended at a Tertiary Care Hospital in Dhaka City
Authors: Sharif Ahmed , Islam Md Rabiul , Faruque Md Golam , Khanam Rashida Akter , Uddin Mohammmad Main , Yusuf Md Abdullah 
Published: September 2019

Background: Thyroid swelling was found in different clinical presentation and demographic characteristics.
Objective: The purpose of the present study was to see the clinical and demographic characteristics as well as the surgical outcomes of thyroid swelling patient.
Methodology: The study was conducted at Mugda Medical College Hospital, Dhaka during the period of April 2017 to March 2018. The diagnosis of thyroid swelling was based on detailed history, thorough clinical examination and relevant investigations, Ultrasonogram and fine needle aspiration cytology (FNAC). All the patients were undergone surgical management and the outcomes were recorded. All the data were compiled and tabulated in order o obtained a statistical and comprehensive results of the study.
Results: A total number of 45 patients were recruited for this study after fulfilling the inclusion and exclusion criteria. This study shows age of the patients ranged from 17 years to 65 years. The highest number of cases (35.6%) belongs to the age group of 31 to 40 years followed by 20% in the age group of 21 to 30 years. Female were higher in frequency (95.6) than male (4.4%). Most of the patients (54%) were from poor socio-economic status. The most common indication were nodular goiter (80%), papillary 13.3%, follicular adenoma 4.4%, and medullary (2.2%). In this study most of the findings showed solid mass in the thyroid gland (55.6%). In this series hemithyroidectomy carried out in 68.9% patients and occupied the top of the list followed by subtotal 22.2%. In this study highest number of complications were recurrent laryngeal nerve paralysis (8.9%).
Conclusion: Young adult female patient is most commonly affected by thyroid swelling and mostly are benign nodular type goiter
Journal of Current and Advance Medical Research 2019;6(2):97-100
Socio-demographic Characteristics of Parkinson’s Disease Patients attended at a Tertiary Care Hospital in Dhaka City
Authors: Islam Md Enayet Ul , Momin Afzal , Sharmin Farzana , Sarkar Provat Kumar , Hoque Md Azharul 
Published: September 2019

Background: Parkinson’s disease occurs in different socio-demographic characteristic people.
Objective: The Purpose of the present study was to see the socio-demographic characteristics of Parkinson’s disease patients attended at a tertiary care hospital in Dhaka city.
Methodology: This cross-sectional study was carried out in the in-patient and out-patient Department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka from July 2012 to December 2013 for a period of one and half year. All patients with Parkinson’s disease who were admitted under department of Medicine and Neurology and also who visited out-patient department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka were taken as study population. Patients who were diagnosed as Parkinson’s disease according to Brain Bank clinical criteria for diagnosis of Parkinson’s disease were included in this study. The demographic and socio-economic characteristics were recorded in a semi-structured questionnaire.
Result: A total number of 40 Parkinson’s patients were recruited for this study. The mean age was 69.15±10.08 years. The male female ratio was found 1.22:1. The majority patients were businessman which was 13(32.5%) cases. The majority of 15(37.5%) patients came from rural area. However, 12(30.0%) patients were in primary level. Furthermore, 21(52.5%) patients came from lower class.
Conclusion: In conclusion elder male rural dwellers are mostly suffering from Parkinson’s disease
Journal of Current and Advance Medical Research 2019;6(2):106-110
Validation of Methods of Identification and Quantitative Determination of Active Ingredients in Films for Treatment of Caries of Dentin
Authors: Berezina E. S. , Golovanenko A. L. , Alekseeva I. V. 
Published: September 2019

Introduction. Even though a wide range of the products for caries treatment is available, the efficiency of its treatment with the traditional methods is 62,5–75,4%. As a result of the set of researches carried out at the Department of Pharmaceutical Technology of the Perm State Pharmaceutical Academy, in cooperation with the Department of Dentistry of the Advanced Training and Professional Retraining Faculty of E. A. Wagner Perm State Medical University, a medical method of moderate and advanced caries treatment with remineralizing gel and films is proposed. During the preparation of the product specification file for the dentin caries treatment film, validation of the methods of the active ingredients quality control has been undertaken.Aim. Validation of the methods of identity tests and of potency assays of dentin caries treatment films.Materials and methods. In order to achieve the aim, active pharmaceutical substances of pharmacopoeial quality have been used. As a base for developing the methods of identity tests the methods with distinctive reactions to cations and anions have been taken. For the potency assay of calcium chloride a complexometric back-titration has been used; photoelectric colorimetry for potassium phosphate dibasic and sodium fluoride; spectrophotometry for chlorhexidine bigluconate. Five production samples of the films were the object of the research.Results and discussion. Basing on the research results, the choice was made in favour of the methods of identity tests that are characterized by negative analytical response when applied to the model mixtures which are free from analyte and placebo, and by positive analytical response when applied to the model mixtures of various composition containing analyte. The validation characteristics of the methods of dentin caries treatment films potency assays, which may be included in the product specification file, have been studied.Conclusion. Validation results show that the chosen methods are specific for both identity tests and potency assays of active substances in the dentin caries treatment films; they are characterized by precision, repeatability and linear dependency in the analytical range of ±30% in regard to the specified active substance concentration in the films. All that allows using them for a reliable quality assessment.
Development and Validation of HPLC-MS/MS Method for Busereline Quantitation in Animal Blood Plasma
Authors: Fisher E. N. , Melnikov E. S. , Shohin I Е. 
Published: September 2019

Introduction. Busereline, being a synthetic gonadotropin-releasing hormone analog, is widely used for hormone-dependent cancer treatment (e.g. prostate cancer and breast cancer). Based on the accumulated scientific data for busereline quantitation in biosamples, the main analytical method that is used for this purpose is high-performance liquid chromatography (HPLC) with fluorescence detection, combined with protein precipitation (TCA 10%) for sample preparation. However, due to several limitations of this method resulting in low sensitivity (at the µg/mL level of concentrations), the HPLC-MS/MS analytical method was chosen for peptide determination in biosamples. The HPLC-MS/MS method is considered to have higher accuracy and specificity. The main sample preparation method for gonadotropin-releasing hormone analogs is solid-phase extraction. In our work, we’ve chosen protein precipitation as an alternative – easier and less laborious biosamples preparation process.Aim. The main objective of this study was the development and validation of HPLC-MS/MS method for busereline quantitation in animal (mini pigs) plasma samples and its further application to pharmacokinetic studies.Materials and methods. Busereline quantitative determination in plasma samples was performed using HPLC-MS/MS method. A protein precipitation procedure (methanol, 1:2, v/v) was used for busereline extraction from pig plasma.Results and discussion. The developed analytical method was validated for selectivity, linearity, matrix effect, accuracy (intra-day, inter-day), precision (intra-day, inter-day), LLOQ, carryover and stability.Conclusion. A new HPLC-MS/MS method for busereline quantitation in blood plasma was developed and successfully validated. The developed method showed linearity over the quantitation range from 1 to 20 ng/mL. The developed method can be successfully applied to busereline pharmacokinetic studies.
SELEKSI SAHAM SYARIAH : PERBANDINGAN ANTARA BURSA EFEK INDONESIA DAN MALAYSIA
Authors: Firmansyah Egi Arvian 
Published: September 2019

Abstract. Islamic stocks are those which do not contradict with the Islamic teachings derived from Al-Quran, Sunnah, hadith and ijtihad of the qualified Islamic scholars. This is a qualitative research comparing the stock screening criteria in order to be categorized as sharia compliant stocks in two developing countries where most of the citizen are Muslims, i.e. Indonesia and Malaysia. As the sharia stock screening is in the field of muamalah and there is no single scholar (or group) accepted by the whole Muslims worldwide, each country sets its own screening criteria through its Islamic scholars by performing ijtihad as an effort to decide the sharia compliant stocks. It was found that there are differences in screening criteria between Indonesia and Malaysia stock exchange. These are based on the fiqh or understanding of the scholars in the two countries as well as the vision and investor to be targeted. The screening criteria need to be continuously improved or revised along with the changing need of investor and stock exchange strategy in collecting the fund especially from Middle East countries requiring sharia compliance.Keywords. ISSI; JII; stock screening; sharia stock selection. Abstrak. Saham Syariah merupakan saham yang tidak bertentangan dengan ajaran Islam yaitu yang bersumber dari Al-Quran, Sunnah, hadist dan ijtihad ulama terkemuka. Penelitian ini merupakan penelitian kualitatif yang membandingkan kriteria seleksi saham untuk dapat dikategorikan ke dalam saham syariah di dua negara berkembang yang penduduknya mayoritas Muslim yaitu Indonesia dan Malaysia. Karena skrining saham syariah termasuk ke dalam aspek muamalah dan tidak adanya ulama yang diterima oleh umat Muslim seluruh dunia untuk menentukan satu hukum yang diterima umum, maka setiap negara dengan ulamanya masing-masing menggunakan pendekatan ijtihad untuk memutuskan saham mana yang dikategorikan sesuai syariah dan tidak. Terdapat perbedaan kriteria seleksi di Indonesia dan Malaysia yang didasarkan pada pemahaman fiqih yang dianut masing-masing negara serta visi dan target investor yang ingin diraih. Metode skrining senantiasa perlu dievaluasi atau direvisi seiring perubahan selera investor dan strategi bursa dalam mengumpulkan dana terutama dari negara-negara Timur Tengah yang memperhatikan aspek kepatuhan pada syariah.Katakunci. ISSI; JII; stock screening; seleksi saham syariah.
PENGARUH EFIKASI DIRI, NORMA SUBJEKTIF, SIKAP BERPERILAKU DAN PENDIDIKAN KEWIRAUSAHAAN TERHADAP INTENSI BERWIRAUSAHA
Authors: Santy Nur , Rahmawati Teti , Hamzah Amir 
Published: September 2019

Abstract. The purpose of this study is to determine the effect of self efficacy, subjective norms, attitudes behave, and entrepreneurship education on the intentions of entrepreneurship the students of Kuningan University .This research use descriptive method, verifikatif, and eksplanatory metoe using questionnaire as the main data gathering tool. In this research, the subject of this research is the students of Kuningan University. Samples in this study are 360 respondents. The data is done by using Multiple Linear Regression Analysis model with SPSS 20 computer program. The result of this research shows that self efficacy, subjective norm, attitude behave, and entrepreneurship education have a positive effect on entrepreneurship intention.Keywords. Self Efficacy; Subjective Norm; Attitude Behavior; Entrepreneurship Education; Entrepreneurship Intention Abstrak. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh efikasi diri, norma subjektif, sikap berperilaku, dan pendidikan kewirausahaan terhadap intensi berwirausaha pada Mahasiswa Universitas Kuningan. Penelitian ini menggunakan metode yang digunakan deskriptif, verifikatif, dan metoe eksplanatorydengan menggunakankuesioner sebagai alat pengumpul data pokok.Dalam penelitian ini yang menjadi subjek dalam penelitian ini adalah Mahasiswa Universitas Kuningan.Sampel dalam penelitian ini sebanyak 360 orang responden. Pengelolaan data dilakukan dengan menggunakan model Analisis Regresi Linear Berganda dengan bantuan program komputer SPSS 20. Hasil dari penelitian ini menunjukkan bahwa efikasi diri, norma subjektif, sikap berperilaku, dan pendidikan kewirausahaan berpengaruh positif terhadap intensi berwirausaha.Kata Kunci. Efikasi diri; Norma Subjektif; Sikap Berperilak; Pendidikan Kewirausahaan; Intensi berwirausaha.
MOTIVASI: EXPECTANCY THEORY DAN PRODUKTIVITAS PENELITIAN
Authors: Garnasih Raden Lestari 
Published: September 2019

Abstract. The purpose of this study is to determine the productivity of research lecturers by using the approach of motivation expectancy theory. Primary data was obtained from 185 respondents ie lecturers in private universities in Pekanbaru city. Data analysis used in this research is multiple regression analysis. The results showed that the lecturer considered the very important thing from the extrinsic motivation that encouraged them to do the research was to get the improvement of functional position, and the lowest level of importance was to obtain the reduction of teaching burden. In view of the importance of intrinsic motivation, lecturers judge that satisfying the need to remain in the field of science today is of paramount importance, and the lowest level of importance as a driver of research is finding better work at other universities.Keywords. Motivation; Expectancy Theory; Research Productivity Abstrak. Tujuan penelitian ini yaitu untuk mengetahui produktivitas penelitian dosen dengan menggunakan pendekatan motivasi expectancy theory. Data primer diperoleh dari 185responden yaitu dosen yang ada di perguruan tinggi swasta di kota Pekanbaru. Analisis data yang digunakan pada penelitian ini adalah analisis regresi berganda. Hasil penelitian menujukkan bahwa dosen menganggap hal yang sangat penting dari motivasi ekstrinsik yang menjadi pendorong mereka melakukan penelitian adalah memperoleh peningkatan jabatan fungsional, dan yang paling rendah tingkat kepentingannya adalah memperoleh pengurangan beban mengajar. Dilihat tingkat kepentingan dari motivasi intrinsic, dosen menilai bahwa memuaskan kebutuhan untuk tetap pada bidang ilmu saat ini adalah yang sangat penting, dan yang paling rendah tingkat kepentingan sebagai pendorong melakukan penelitian adalah menemukan pekerjaan yang lebih baik pada perguruan tinggi yang lain.Katakunci. Motivasi; Expectancy Theory; Produktivitas Penelitian.
PENGARUH TINGKAT PENDIDIKAN TERHADAP PRESTASI KERJA KARYAWAN MELALUI MOTIVASI KERJA SEBAGAI INTERVENING
Authors: Hernidatiatin Lis Tatin , Susijawati Noveria 
Published: September 2019

Abstract. This study is aimed to analyze the direct and indirect effect of educational level on employee performance through work motivation as an intervening variable at PT. Kereta Api (Persero) Regional Operations (DAOP) 3 Cirebon. The method used in this research is associative method and data collection technique used is the field research (observation, interview, questionnaire) and literature study. To determine the size of the sample, the study used the Slovin formula while to analyse data the researchers performed validity, reliability and classical assumption test (normality, multicollinearity, heteroscedasticity and autocorrelation test), path analysis, t hypothesis testing. The results of path analysis showed that the level of education directly impacted to employee performance and indirectly to work motivation (an intervening variable) and finally to employee performance. Due to the fact that the direct correlation coefficient is greater than the indirect correlation coefficient, it can be said that the true relationship is direct correlation.Keywords. Level of education; work motivation; job performance. Abstrak. Penelitian ini bertujuan untuk menganalisis pengaruh langsung tingkat pendidikan terhadap prestasi kerja karyawan dan pengaruh tidak langsung tingkat pendidikan terhadap prestasi kerja karyawan melalui motivasi kerja sebagai variabel intervening pada PT. Kereta Api (Persero) Daerah Operasi (DAOP) 3 Cirebon. Metode yang akan digunakan dalam penelitian ini adalah metode Asosiatif. Tehnik pengumpulan data yang digunakan adalah Riset Lapangan (Observasi, Wawancara, Angket) dan Riset Kepustakaan. Untuk menentukan ukuran sampel menggunakan rumus Slovin. Penelitian ini menggunakan metode analisis data yang terdiri dari Uji validitas, Uji reliabilitas, Uji Asumsi Klasik (Uji Normalitas, Uji Multikolonearitas, Uji Heteroskedastisitas, Uji Autokorelasi), Analisis Jalur, Uji t Hipotesis. Hasil analisis jalur menunjukkan bahwa tingkat pendidikan dapat berpengaruh langsung ke prestasi kerja karyawan dan dapat juga berpengaruh tidak langsung yaitu dari tingkat pendidikan ke motivasi kerja (sebagai variabel intervening) lalu ke prestasi kerja karyawan. Oleh karena koefisien hubungan langsung lebih besar dari koefisien hubungan tidak langsung, maka dapat dikatakan bahwa hubungan yang sebenarnya adalah langsung.Katakunci. Tingkat, pendidikan; motivasi kerja, prestasi kerja.
Financial Distress pada PT Panasia Indo Resources Tbk
Authors: Nugraha Akhbar , Fajar Catur Martian 
Published: September 2019

Abstract. Bankruptcy in the company is characterized by a continuous decline in financial performance. The purpose of this study is to assess the influence of current ratio, debt to assets ratio, working capital turnover and net profit margin of the company on financial distress at PT Panasia Indo Resources Tbk. used is the explanatory survey. The result of the research shows that the existence of negative and insignificant influence of current ratio in predicting financial distress, debt to asset ratio has positive and insignificant influence in predicting Financial distress, working capital turnover has negative and insignificant influence in predicting Financial distress and net profit margin has a negative and significant influence in predicting Financial distress. Simultaneously, the current ratio, debt to assets ratio, working capital turnover and net profit margin jointly have a significant effect on the condition of Financial distress at PT Panasia Indo Resources Tbk. Keywords: Current ratio; Debt to assets ratio; Working capital turnover; Net profit margin; Financial distress Abstrak. Kebangkrutan diperusahaan ditandai dengan adanya penurunan kinerja keuangan yang terjadi terus-menerus. Tujuan penelitian ini adalah untuk mengkaji pengaruh current ratio, debt to assets ratio, working capital turnover dan net profit margin perusahaan pada financial distress pada PT Panasia Indo Resources Tbk. Metode penelitian yang digunakan adalah explanatory survey. Hasil penelitian menunjukkan bahwa adanya pengaruh negatif dan tidak signifikan current ratio dalam memprediksi financial distress, debt to assets ratio mempunyai pengaruh positif dan tidak signifikan dalam memprediksi Financial distress, working capital turnover mempunyai pengaruh negatif dan tidak signifikan dalam memprediksi Financial distress dan net profit margin mempunyai pengaruh negatif dan signifikan dalam memprediksi Financial distress. Secara simultan current ratio, debt to assets ratio, working capital turnover dan net profit margin secara bersama-sama berpengaruh signifikan terhadap kondisi Financial distress pada PT Panasia Indo Resources Tbk. Katakunci: Current ratio; Debt to assets ratio; Working capital turnover; Net profit margin; Financial distress
Pengaruh Kompetensi dan Kecerdasan Emosional Terhadap Kinerja Pegawai
Authors: Ardiansyah Yusuf , Sulistiyowati Lisa Harry 
Published: September 2019

Abstract : The purpose of this study is to determine the effect of competence variables and emotional intelligence on employee performance. The research method used is quantitative research method. The population in this study is the employee of Education and Culture Office of Kuningan Regency with the number of 97 people. Sampling technique used is a sampling technique saturated, so that all members of the population sampled as many as 97 people. Data retrieval technique using questionnaire with scale measurement instrument using a likert scale. Data analysis techniques used using multiple regression analysis. The results showed that there is a positive and significant influence both partially and simultaneously, between the competence variable and emotional intelligence on the performance of employees. Keyword : Competency; Emotional Intelligence; Employee Performance Abstrak.: Tujuan peneltian ini adalah untuk mengetahui pengaruh variabel kompetensi dan kecerdasan emosional terhadap kinerja pegawai. Metode penelitian yang digunakan adalah metode penelitian kuantitatif. Populasi dalam penelitian ini adalah Pegawai Dinas Pendidikan dan Kebudayaan Kabupaten Kuningan dengan jumlah sebanyak 97 orang. Teknik penarikan sampel yang digunakan adalah teknik sampling jenuh, sehingga seluruh anggota populasi dijadikan sampel yaitu sebanyak 97 orang. Teknik penarikan data menggunakan kuesioner dengan skala pengukuran instrumen mengunakan skala likert. Teknik analisis data yang digunakan menggunkan analisis regresi ganda. Hasil penelitian menunjukan bahwa terdapat pengaruh yang positif dan signifikan baik secara parsial maupun simultan, antara variabel kompetensi dan kecerdasan emosional terhadap kinerja pegawai. Kata Kunci : Kompetensi; Kecerdasan Emosional; Kinerja Pegawai