bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Bayesian‐weighted approach to predicting the number of newly discovered rare species
Authors: Shen Tsung‐Jen , Chen Youhua 
Published: November 2018

AbstractIn natural ecological communities, most species are rare and thus susceptible to extinction. Consequently, the prediction and identification of rare species are of enormous value for conservation purposes. How many newly found species will be rare in the next field survey? We took a Bayesian viewpoint and used observed species abundance information in an ecological sample to develop an accurate way to estimate the number of new rare species (e.g., singletons, doubletons, and tripletons) in an additional unknown sample. A similar method has been developed for incidence‐based data sets. Five seminumerical tests (3 abundance cases and 2 incidence cases) showed that our proposed Bayesian‐weight estimator accurately predicted the number of new rare species with low relative bias and low relative root mean squared error and, accordingly, high accuracy. Finally, we applied the proposed estimator to 6 conservation‐directed empirical data sets (3 abundance cases and 3 incidence cases) and found the prediction of new rare species was quite accurate; the 95% CI covered the true observed value very well in most cases. Our estimator performed similarly to or better than an unweighted estimator derived from Chao et al. and performed consistently better than the naïve unweighted estimator. We recommend our Bayesian‐weight estimator for conservation applications, although the unweighted estimator of Chao et al. may be better under some circumstances. We provide an R package RSE (rare species estimation) at https://github.com/ecomol/RSE for implementation of the estimators.
Post‐9/11 Masculinist Incursions in Iraq and Afghanistan: Women’s Bodies as Bullets in Imperialist Agendas
Authors: Ridouane Abdelmajid 
Published: November 2018

AbstractThe gender question in the Middle East now serves ends beyond the local. It may be registered within a cluster of international patriarchal war‐promoting discourses that find tremendous benefit in the historical bulk of literature that demonizes the Middle Eastern male and victimizes the female. This article attempts to defend two related arguments, both of which are well served by Foucault’s Biopolitics (Foucault, The birth of biopolitics), in which he correlates between territorial control and the violence inherent to any hegemony’s preoccupation with the body (i.e., the Middle Eastern/Muslim woman’s body) and Achille Mbembe’s theory of Necroplotics and its designation of who “may live” and who “must die” (Mbembé, 2003:11–4). I argue that in the post‐9/11 era, the world has witnessed a globalist civilizational masculinist incursion on its demonized Middle Eastern/Islamic Other. The militaristic discourse at work seems to be self‐appropriating the Middle Eastern/Muslim woman’s body as a site of sexual oppression and (mis)using it to its own means. The impetus of the 9/11 necropolitics, aggressively transposes gender dialog/conflict in the Middle East/Muslim countries from a benign social and intellectual interface, where different alliances may be negotiated, to an aggressive militaristic zone, where the “bogeyman” must “die.”
Phylogenetically weighted regression: A method for modelling non‐stationarity on evolutionary trees
Authors: Davies T. Jonathan , Regetz James , Wolkovich Elizabeth M. , McGill Brian J. 
Published: November 2018

AbstractAimClosely related species tend to resemble each other in their morphology and ecology because of shared ancestry. When exploring correlations between species traits, therefore, species cannot be treated as statistically independent. Phylogenetic comparative methods (PCMs) attempt to correct statistically for this shared evolutionary history. Almost all such approaches, however, assume that correlations between traits are constant across the tips of the tree, which we refer to as phylogenetic stationarity. We suggest that this assumption of phylogenetic stationarity might be often violated and that relationships between species traits might evolve alongside clades, for example, owing to the effects of unmeasured traits or other latent variables. Specific examples range from shifts in allometric scaling relationships between clades (e.g., basal metabolic rate and body mass in endotherms, and tree diameter and biomass in trees) to the differing relationship between leaf mass per area and shade tolerance in deciduous versus evergreen trees and shrubs.InnovationHere, we introduce an exploratory modelling framework, phylogenetically weighted regression, which represents an extension of geographically weighted regression (GWR) used in spatial studies, to allow non‐stationarity in model parameters across a phylogenetic tree. We demonstrate our approach using empirical data on flowering time and seed mass from a well‐studied plant community in southeastern Sweden. Our model reveals strong, diverging trends across the phylogeny, including changes in the sign of the relationship between clades.Main conclusionsBy allowing for phylogenetic non‐stationarity, we are able to detect shifting relationships among species traits that would be obscured in traditional PCMs; thus, we suggest that PWR might be an important exploratory tool in the search for key missing variables in comparative analyses.
Morphological diversity of freshwater fishes differs between realms, but morphologically extreme species are widespread
Authors: Su Guohuan , Villéger Sébastien , Brosse Sébastien 
Published: November 2018

AbstractAimThe aim was to analyse the morphological diversity of the world freshwater fish fauna. We tested to which extent the distributions of morphological traits are supported by extreme morphologies and how those extreme morphologies are distributed among realms and affect the functional vulnerability. We also analysed the contribution of between‐ and within‐order morphological variability to the morphological differences between realms.Major taxa studiedFreshwater fish.LocationGlobal.Time period1960s–2010s.MethodsWe used a global database of freshwater fishes from the six realms. Ten morphological traits were measured on 9,150 species, that is, 75% of the ca. 13,000 freshwater fish species. A principal components analysis was conducted to combine the 10 traits into a multidimensional space. We used Kolmogorov–Smirnov tests to compare the difference in morphological diversity between the six realms and between and within the major fish orders. We then identified the morphologically extreme species and quantified their contributions to the morphological range to assess the functional vulnerability and redundancy of fish faunas in the six biogeographical realms for freshwater ecosystems.ResultsWe report a strong morphological variability among freshwater fishes of the world, with significant morphological differences among realm fish faunas, caused by an interplay between taxonomic composition of the realm faunas and morphological differences within orders among the realms. Morphologically extreme species accounted for a large percentage of the filling of the global morphological space and are distributed throughout the world.Main conclusionsFish morphological diversity is largely supported by a few species with extreme trait combinations, indicating that functional vulnerability exists throughout the world. Our results suggest that more attention should be paid to these morphologically extreme species and that they should be protected to ensure the sustainability of functions they support.
Differences in Rural and Urban Health Information Access and Use
Authors: Chen Xuewei , Orom Heather , Hay Jennifer L. , Waters Erika A. , Schofield Elizabeth , Li Yuelin , Kiviniemi Marc T. 
Published: November 2018

AbstractPurposeRural residents may have lower access to and use of certain health information sources relative to urban residents. We investigated differences in information source access and use between rural and urban US adults and whether having low health literacy might exacerbate rural disparities in access to and use of health information.MethodsSix hundred participants (50% rural) completed an online survey about access and use of 25 health information sources. We used logistic regression models to test associations between rurality and access to and use of health information sources and whether rurality interacted with health literacy to predict the access and use.FindingsCompared to urban residents, rural residents had lower access to health information from sources including primary care providers, specialist doctors, blogs, and magazines, and less use of search engines. After accounting for sociodemographics, rural residents only had lower access to specialist doctors than urban residents. Rural residents with limited health literacy had lower access to mass media and scientific literature but higher use of corporations/companies than rural residents with adequate health literacy and urban residents regardless of health literacy level.ConclusionsSome differences in access to and use of health information sources may be accounted for by sociodemographic differences between rural and urban populations. There may be structural barriers such as shortage of specialist doctors and limited media exposure that make it harder for rural residents to access health information, especially those with limited health literacy.
A review of inorganic UV filters zinc oxide and titanium dioxide
Authors: Schneider Samantha L. , Lim Henry W. 
Published: November 2018

SummaryPhotoprotection has become integral in the prevention of keratinocyte cancer and photoaging. Organic ultraviolet (UV) filters such as oxybenzone and octinoxate have become controversial due to their potential impact on the environmental and their potential human health risks. As such, inorganic UV filters, zinc oxide (ZnO) and titanium dioxide (TiO2), have become paramount in discussions about photoprotection. ZnO and TiO2 are used in sunscreens as nanoparticles, which denotes a size <100 nm. The smaller size of these mineral particles increases their cosmetic acceptability by users as they are much less visible after application. ZnO has a broad UVA‐UVB absorption curve, while TiO2 provides better UVB protection. Overall, the human health risks with inorganic filters are extremely low given a lack of percutaneous absorption; however, there is potential risk when exposed via inhalation, prompting recommendations against spray sunscreen products with nanoparticles. At this time, the known risk to the environment is low though the risk stratification may evolve with increasing usage of these filters and higher environmental concentrations. The continued practice of photoprotection is critical. The public should be counseled to seek shade, use photoprotective clothing including hats and glasses in addition to sunscreens on sun‐exposed skin. For those concerned about emerging evidence of environmental impact of organic UV filters, based on current evidence, ZnO and TiO2‐containing sunscreens are safe alternatives.
Repeated exposure to temperature variation exacerbates airway inflammation through TRPA1 in a mouse model of asthma
Authors: Du Chenqiu , Kang Jun , Yu Wei , Chen Mingqing , Li Baizhan , Liu Hong , Wang Han 
Published: November 2018

ABSTRACTBackground and objectiveStudies from epidemiology suggest that ambient temperature is one of the underlying triggers and potential causes of asthma. The aim of this study was to examine the impact and the molecular mechanism of temperature‐invoked airway inflammation using an experimental model of asthma in BALB/c mice.MethodsMice were exposed to different temperature conditions (steady 26°C, 26°C/18°C cycle, 26°C/10°C cycle) and received sensitization and challenge of ovalbumin (OVA) during a 21‐day period. HC030031, a selective transient receptor potential A1 (TRPA1) channel blocker, was used to investigate the underlying mechanism of TRPA1 in ‘asthmatic’ airways. After the final OVA challenge, in vivo lung function was measured, and bronchoalveolar lavage fluid (BALF) and pulmonary inflammation were assessed.ResultsThe temperature variations, especially the largest temperature difference (16°C), exacerbated airway inflammation in OVA‐induced mice, increasing the levels of serum total‐IgE (immunoglobulin E) and IgG1, inflammatory cells and cytokines in BALF. Analysis of histopathological changes and lung function verified that repeated exposure to very cold and changed temperatures aggravated airway hyperresponsiveness (AHR). Significant upregulation of TRPA1 expression was revealed by immunohistochemistry in the presence of the largest temperature variation (26°C/10°C cycle), while administration of HC030031 successfully inhibited TRPA1 expression, thus attenuating the asthma‐like pathological features.ConclusionRepeated exposure to temperature variation exacerbated experimental ‘asthma’ and TRPA1 mediated this temperature‐dependent inflammatory effect.
Rethinking Risk Assessment for Public Utility Safety Regulation
Authors: Danner Carl , Schulman Paul 
Published: November 2018

AbstractTo aid in their safety oversight of large‐scale, potentially dangerous energy and water infrastructure and transportation systems, public utility regulatory agencies increasingly seek to use formal risk assessment models. Yet some of the approaches to risk assessment used by utilities and their regulators may be less useful for this purpose than is supposed. These approaches often do not reflect the current state of the art in risk assessment strategy and methodology. This essay explores why utilities and regulatory agencies might embrace risk assessment techniques that do not sufficiently assess organizational and managerial factors as drivers of risk, nor that adequately represent important uncertainties surrounding risk calculations. Further, it describes why, in the special legal, political, and administrative world of the typical public utility regulator, strategies to identify and mitigate formally specified risks might actually diverge from the regulatory promotion of “safety.” Some improvements are suggested that can be made in risk assessment approaches to support more fully the safety oversight objectives of public regulatory agencies, with examples from “high‐reliability organizations” (HROs) that have successfully merged the management of safety with the management of risk. Finally, given the limitations of their current risk assessments and the lessons from HROs, four specific assurances are suggested that regulatory agencies should seek for themselves and the public as objectives in their safety oversight of public utilities.
Single‐donor spray‐dried plasma
Authors: Liu Qiyong Peter , Carney Ryan , Sohn Jihae , Sundaram Sruthi , Fell Mary‐Anne 
Published: November 2018

BACKGROUNDDried plasma is logistically superior for hemostasis management because it can be transported and stored under nonfrozen conditions and quickly reconstituted at the point of care, enabling prehospital administration. Velico Medical has developed a spray‐drying system to be integrated into routine blood center work streams for spray drying single donor plasma units. This study compared the quality of the spray‐dried plasma (on‐demand plasma [ODP]) with fresh frozen plasma (FFP).STUDY DESIGN AND METHODSODP units (n = 60) were manufactured from never frozen fresh plasma, which was pretreated with glycine–hydrochloric acid and stored at 1to 6°C. Paired aliquots were frozen and stored at −18°C or less. After 31 to 33 days, ODP samples were reconstituted with water for injection and comprehensively characterized in parallel with paired FFP. The quantities of plasma dried and rehydration fluid were predetermined, ensuring comparable total protein concentration in ODP and paired FFP.RESULTSODP is comparable to FFP in global coagulation function as assessed by activated partial thromboplastin time and prothrombin time and in clot formation evaluated by thrombelastography. Compared to FFP, ODP had greater than 80% levels of functional coagulation factors and related proteins and chemistry analytes except for Factor XIII (74%). Pretreatment mitigated cleavage of high‐molecular‐weight von Willebrand factor multimers by spray drying and resulted in 60% vWF:ristocetin cofactor activity in ODP compared to FFP.CONCLUSIONSODP demonstrates coagulation function comparable to that of FFP. The spray drying system can be implemented in blood centers and is capable of producing units of ODP.
Lymphopaenia as a predictor of sarcoidosis in patients with a first episode of uveitis
Authors: Groen-Hakan Fahriye , Eurelings Laura , Rothova Aniki , van Laar Jan 
Published: November 2018

Background/aimsThe diagnostic properties of conventional diagnostic tests (ACE and chest radiography) for sarcoidosis-associated uveitis are not ideal. The diagnostic value of lymphopaenia for sarcoidosis-associated uveitis is investigated.MethodsA retrospective study of 191 consecutive patients with a first uveitis episode visiting the ophthalmology department (Erasmus Medical Center, Rotterdam, The Netherlands). Receiver operating characteristics (ROC) analysis was performed and compared with known ROC values from literature of conventional diagnostic tests for sarcoidosis-associated uveitis. An ideal cut-off was determined for lymphopaenia by calculation of the highest Youden index.ResultsOut of all patients with first uveitis attack, 32/191 or 17% were subsequently diagnosed with biopsy-proven or radiological diagnosis of sarcoidosis. Lymphopaenia (<1.5×109/L) was significantly more often observed in patients with sarcoidosis-associated uveitis compared with patients with non-sarcoidosis-associated uveitis (p<0.05). The sensitivity and specificity of lymphopaenia was 75 % and 77 %, respectively. The optimal cut-off for lymphopaenia for diagnosing sarcoidosis-associated uveitis was 1.47 ×109/L. Lymphopaenia resulted in a 12.0 (95% CI 4.7 to 30.5 fold risk for having sarcoidosis, corrected for sex, race and age at onset of uveitis in patients with a first uveitis attack.ConclusionLymphopaenia is a non-invasive and useful marker for diagnosing sarcoidosis-associated uveitis.
Diagnostic accuracy of imaging brain vesicular monoamine transporter type 2 (VMAT2) in clinically uncertain parkinsonian syndrome (CUPS): a 3-year follow-up study in community patients
Authors: Xu San San , Alexander Paschal K , Lie Yenni , Dore Vincent , Bozinovski Svetlana , Mulligan Rachel S , Young Kenneth , Villemagne Victor L , Rowe Christopher C 
Published: November 2018

ObjectivesTo further validate the diagnostic utility of18F-AV-133 vesicular monoamine transporter type 2 (VMAT2) positron emission tomography (PET) in patients with clinically uncertain parkinsonian syndromes (CUPS) by comparison to clinical diagnosis at 3 years follow-up.Design, setting and participantsIn a previous study, we reported that18F-AV-133 PET in community patients with CUPS changed diagnosis and management and increased diagnostic confidence. The current diagnosis of this cohort was obtained from the patient and treating specialist and compared with the diagnosis suggested 3 years earlier by the18F-AV-133 PET. A second18F-AV-133 PET was available in those with a discordant or inconclusive final diagnosis.Study outcome measuresThe primary end point was the proportion of patients who had a follow-up clinical diagnosis, which was concordant with their initial18F-AV-133 PET scan. Secondary end points were the proportion of patients who had the same diagnosis at follow-up as that reached after the initial scan and the stability of diagnostic changes made after the first scan.Results81 of the 85 patients previously recruited to the CUPS study had follow-up of which 79 had a clinical diagnosis and 2 remained CUPS. The diagnosis was in agreement with the initial18F-AV-133 PET scan result in 74 cases. Five patients had a discordant diagnosis; one patient with rubral tremor had a severely abnormal scan that had worsened when rescanned; four cases with normal initial and repeat scans had a clinical diagnosis of Parkinson’s disease. Two patients with suspected genetic disorders remained classified as CUPS and both had normal scans. In the 24 CUPS cohort patients where18F-AV-133 PET initially changed diagnosis, this change was supported by follow-up diagnosis in all but the one rubral tremor case.Conclusion18F-AV-133 PET is a useful tool in improving diagnostic accuracy in CUPS providing results and diagnostic changes that remain robust after 3 years follow-up.
Influence of Ba/Ti ratio on PTCR effect of Bam(Ti1−xNbx)O3 ceramics prepared by the reduction sintering-reoxidation method
Authors: Cheng Xuxin , Chen Xiaoming , Li Xiaoxia , Cui Haining , Xiong Chao 
Published: November 2018

In this work, we investigate the influences of Ba/Ti ratio and sintering conditions on the characteristics of positive temperature coefficient of resistance (PTCR) and electrical properties of Ba[Formula: see text](Ti[Formula: see text]Nb[Formula: see text])O3 (BTN) ceramics. The ceramics were fired at 1190[Formula: see text]C for 0.5–6.0 h in a reducing atmosphere and then reoxidized at 600–650[Formula: see text]C for 0–8 h. The Ba/Ti ratio [Formula: see text] affected the electrical properties and PTCR effect of the BTN specimens. The room-temperature (RT) resistance of the BTN samples initially decreased [Formula: see text] and then increased [Formula: see text] as the Ba/Ti ratio increased. Moreover, BTN ceramics exhibit a pronounced PTCR effect, with a resistance jump greater by 3.0 orders of magnitude and a low 0.1 [Formula: see text] RT resistance at a low reoxidation temperature of 600[Formula: see text]C after sintering under a reducing atmosphere. Furthermore, the average sample grain size increased along with the Ba/Ti ratio. In addition, the influence of the sintering time and the reoxidation time on the electrical properties and the PTCR effect were also investigated.
An electromagnetic energy harvester using ferrofluid as a lubricant
Authors: Wang Siqi , Liu Yongkai , Li Decai , Wang Hujun 
Published: November 2018

An electromagnetic generator with magnetic spring and ferrofluid is proposed and designed to harvest low-frequency vibration energy from human body motion. The magnetic spring is formed by gravity and magnetic repulsive force between the fixed and the moving permanent magnets. The ferrofluid is aggregated at both ends of the moving permanent magnet, and the ferrofluid layer between the plastic tube wall and permanent magnet can remove the solid-friction as a fluid lubricant. The electromagnetic generator is used to harvest human motion energy. The measured average load powers of electromagnetic generator with ferrofluid 1.5 g from human body motion are 1.3 mW and 7.5 mW during walking and low running, respectively, which is 30 times more than the measured average power of generator without ferrofluid.