bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of Patient-Reported Outcome Measures in Quality Oncology Practice Initiative–Registered Practices: Results of a National Survey
Authors: Zhang Biqi , Lloyd Whit , Jahanzeb Mohammad , Hassett Michael J. 
Published: September 2018

Purpose: Measuring patient-reported outcomes (PROs) in clinical practice has been associated with improved survival and quality of life for patients with cancer. However, this application of PROs is relatively new, and little is known about how practices collect PROs, which PROs are measured, and what challenges are met in implementation. Methods: We surveyed Quality Oncology Practice Initiative–registered practices in December 2015 to understand the current state of PROs use and identify areas where implementation support may be needed. PRO collectors were asked to describe their views, practices, and challenges with implementation; noncollectors were asked about their interest in and perceived barriers to collection. Results: Eighty-nine practices (38% of those that viewed the participation request) completed ≥ 50% of the survey and comprised the analytic sample. Most (79%) responders noted that collecting PROs was a high priority; slightly fewer actually collected PROs (69%). Most collectors (79%) were affiliated with hospitals or medical centers, and nearly all (94%) had electronic health records (EHRs). Collectors saw more patients per week than noncollectors ( P < .01). The PROs used by collectors addressed several topics, including patient distress (78%), symptoms (76%), and experience or satisfaction (70%). Perceived implementation challenges were similar for collectors and noncollectors: patient unwillingness to complete questionnaires and insufficient staff support; noncollectors additionally cited lack of PRO integration in the electronic health records. Conclusion: Widespread agreement that PRO collection is important has led to early adoption among a sizable minority of Quality Oncology Practice Initiative practices. Reaching consensus regarding which PROs are meaningful and developing and sharing best-practices that overcome implementation barriers could facilitate implementation and maximize PRO utility.
VAMP7 Regulates Autophagosome Formation by Supporting Atg9a Functions in Pancreatic β-Cells From Male Mice
Authors: Aoyagi Kyota , Itakura Makoto , Fukutomi Toshiyuki , Nishiwaki Chiyono , Nakamichi Yoko , Torii Seiji , Makiyama Tomohiko , Harada Akihiro , Ohara-Imaizumi Mica 
Published: September 2018

Abstract
Dysfunctional mitochondria are observed in β-cells of diabetic patients, which are eventually removed by autophagy. Vesicle-associated membrane protein (VAMP)7, a vesicular SNARE protein, regulates autophagosome formation to maintain mitochondrial homeostasis and control insulin secretion in pancreatic β-cells. However, its molecular mechanism is largely unknown. In this study, we investigated the molecular mechanism of VAMP7-dependent autophagosome formation using VAMP7-deficient β-cells and β-cell–derived Min6 cells. VAMP7 localized in autophagy-related (Atg)9a–resident vesicles of recycling endosomes (REs), which contributed to autophagosome formation, and it interacted with Hrb, Syntaxin16, and SNAP-47. Hrb recruited VAMP7 and Atg9a from the plasma membrane to REs. Syntaxin16 and SNAP-47 mediated autophagosome formation at a step later than the proper localization of VAMP7 to Atg9a-resident vesicles. Knockdown of Hrb, Syntaxin16, and SNAP-47 resulted in defective autophagosome formation, accumulation of dysfunctional mitochondria, and impairment of glucose-stimulated insulin secretion. Our data indicate that VAMP7 and Atg9a are initially recruited to REs to organize VAMP7 and Atg9a-resident vesicles in an Hrb-dependent manner. Additionally, VAMP7 forms a SNARE complex with Syntaxin16 and SNAP-47, which may cause fusions of Atg9a-resident vesicles during autophagosome formation. Thus, VAMP7 participates in autophagosome formation by supporting Atg9a functions that contribute to maintenance of mitochondrial quality.
Optimizing the Geometry of Wildlife Corridors in Conservation Reserve Design
Authors: St John Rachel , Tóth Sándor F. , Zabinsky Zelda B. 
Published: September 2018

Wildlife corridors are often used to connect critical habitat for species protection. Mixed integer programming models have been used in the past to create wildlife corridors, but they lack the capacity to control corridor geometry. We propose an approach that employs path planning techniques from artificial intelligence to account for and control corridor geometry, such as width and length. By combining path planning with network optimization, our approach allows the user to control and optimize the geometric characteristics of wildlife corridors. We illustrate our approach on two realistic landscapes and present numerical results on several computer-generated landscapes. The computational results indicate that this approach is efficient and can address problems controlling corridor geometry that were previously thought intractable. The approach has potential applications in such areas as the selection of routes or barrier construction problems, an example of which is firebreak design.Data are available at https://doi.org/10.1287/opre.2018.1758 .
Os movimentos populares e o sindicalismo brasileiros face aos processos de integração regional na América do Sul | Popular movements and trade unions due to South American regional integration processes
Authors: De Assumpção Tatiana Berringer 
Published: September 2018

Este artigo analisa a ação dos movimentos populares e do sindicalismo brasileiros face aos processos de integração regional durante os governos PT (2003-2016). Buscamos entender como atuaram o sindicalismo e os movimentos populares que participaram da Campanha contra a Área de livre Comércio das Américas (ALCA) nos dez anos seguintes ao arquivamento da proposta. Acreditamos que apesar de uma diferença estratégica não existe uma contradição no seio das classes populares uma vez que as iniciativas se complementam. Há formas e vias diferentes de construção dos processos de integração regional: de um lado, o sindicalismo aposta mais nos espaços institucionais do Mercado Comum do Sul (Mercosul) e da União das Nações Sul-americanas (Unasul), e de outro lado, os movimentos populares jogam mais força na articulação dos Movimentos Sociais da Aliança Bolivariana para a Nossa América (ALBA).ABSTRACTThis article does an analysis of popular movements and trade unions actions due to the regional integration process on PT´s governments (2003-2016). We have tried to understand how the organizations that have been participating in the fighting against FTAA have done during the next ten years after that death of that project. We sustain that despite a difference there is no strategic contradiction inside Brazilian popular classes, it is because the initiatives are complementary. There are different ways on the regional integration process: on the one side, the trade unions have a focus on institutional spaces inside Southern Comum Market (Mercosur) and South America Union Nations (Unasur), and on the other side, the popular movements play an important role on the Social Movements Articulation of Bolivarian Alliance of Americas (ALBA).Palavras-chave: integração regional; ALCA; Mercosul; sindicalismo; movimentos populares.Keywords: regional integration; FTAA; Mercosur; trade unions; popular movements.Recebido em 08 de Abril de 2018 | Received on April 08, 2018Aceito em 11 de Setembro de 2018 | Accepted on September 11, 2018DOI
Skeletal muscle regeneration by extracellular matrix biological scaffold: a case report
Authors: Zhao Jane Y. , Bass Kathryn D. 
Published: September 2018

A case report of a 17-year-old female with a complex, non-healing, two-month-old wound, wherein exposed fibula was evident. On assessment, the wound measured 35cm in length, 3cm in width, and was 1cm deep, along the lateral aspect of the left lower leg. A rim of granulation tissue was visible along the wound edge. The exposed bone measured 20cm in length, and was 3cm wide. Porcine-derived, extracellular matrix (ECM) biological scaffold was placed on the wound bed to facilitate regeneration of the patient's skeletal muscle. The patient healed without incident postoperatively and was able to regain her ambulatory ability. This technique has, in the authors' experience, proved successful and without complication in complex non-healing wound cases, particularly in patients who have lost a large volume of skeletal muscle. The authors believe that patients and surgeons would benefit from early consideration of ECM biological scaffolds in similar types of large, open, and complex wounds.
The enigma of atypical femoral fractures
Authors: Larsen Morten Schultz , Schmal Hagen 
Published: September 2018

Atypical femoral fractures (AFF) are stress or ‘insufficiency’ fractures, often complicated by the use of bisphosphonates or other bone turnover inhibitors. While these drugs are beneficial for the intact osteoporotic bone, they probably prevent a stress fracture from healing which thus progresses to a complete fracture. Key features of atypical femoral fractures, essential for the diagnosis, are: location in the subtrochanteric region and diaphysis; lack of trauma history and comminution; and a transverse or short oblique configuration. The relative risk of patients developing an atypical femoral fracture when taking bisphosphonates is high; however, the absolute risk of these fractures in patients on bisphosphonates is low, ranging from 3.2 to 50 cases per 100,000 person-years. Treatment strategy in patients with AFF involves: radiograph of the contralateral side (computed tomography and magnetic resonance imaging should also be considered); dietary calcium and vitamin D supplementation should be prescribed following assessment; bisphosphonates or other potent antiresorptive agents should be discontinued; prophylactic surgical treatment of incomplete AFF with cephalomedullary nail, unless pain free; cephalomedullary nailing for surgical fixation of complete fractures; avoidance of gaps in the lateral and anterior cortex; avoidance of varus malreduction. Cite this article: EFORT Open Rev 2018;3:494-500. DOI: 10.1302/2058-5241.3.170070.
Aktualizacja, fragmentaryzacja, trwanie – próba opisu perspektyw czasowych współczesnego dokumentu
Authors: Boratyn Katarzyna 
Published: September 2018

The article describes certain changes that have taken place over the last several years in the temporal perspective found in documentary films. Humanity’s current technological and media environment are influencing the documentary’s content and means of expression. They express a “universal present”, as Mirosław Przylipiak has pointed out, under the influence of television, and the former dominance of statements addressed to the camera gave way to looks into the past. At present, the documentary is once again shifting its orientation toward a strictly defined and changing form of the present. Time in the temporally non-linear works commonly found among contemporary documentaries has become fragmented and individualized. There is also a tendency in non-fiction works to strive for immersion – focusing on the experience of time rather than the telling of a story.
A checklist of the benthic marine algae of the Northern Arabian Sea coast of the Sultanate of Oman
Authors: Wynne Michael J. 
Published: September 2018

Abstract
An updated checklist of the benthic marine algae (seaweeds) of the Northern Arabian Sea coast of the Sultanate of Oman is presented, with a total of 402 taxa, consisting of 75 taxa of brown algae (Phaeophyceae), 238 taxa of red algae (Rhodophyta), and 89 taxa of green algae (Chlorophyta). Obsolete names and taxonomic synonyms as well as information on mis-identified names are provided. The classification in many instances reflects new ideas derived from the results of molecular-based phylogenetics. A total of 18 taxa of benthic marine algae are newly reported for Oman.
More than meets the eye: regional specialisation and microbial cover of the blade of Porphyra umbilicalis (Bangiophyceae, Rhodophyta)
Authors: Royer Charlotte J. , Blouin Nicolas A. , Brawley Susan H. 
Published: September 2018

Abstract
Completion of the Porphyra umbilicalis genome and ongoing research on this species by many investigators suggest the need for wider appreciation of regional specialisation of the P. umbilicalis blade. Here we use light and electron microscopy to describe four distinct regions of the blade: rhizoid cells with abundant floridean starch, vegetative cells, differentiating neutral sporangia, and mature neutral spores. The holdfast, densely covered by microorganisms, presents an intriguing biomechanical structure: thousands of very thin, long rhizoid tips course through the thick, secreted polysaccharide to the substratum. Wild blades in culture have more microorganisms than when collected, including filamentous cyanobacteria.
Poly(N-octyl-4-vinylpyridinium bromide) copolymers in aqueous solutions: potentiometric and thermodynamic studies
Authors: Tennouga Lahcene , Bensalah Wassila , Mansri Ali 
Published: September 2018

Abstract
In this work, the P4VP was synthesized by radical polymerization. The quaternization of this polymer by octyl bromide leads to the two copolymers [poly(N-octyl-4-vinylpyridinium bromide] named P4VPC8Br 48.8% and P4VPC8Br 72%. The thermodynamic behavior associated with the potentiometric titration of the copolymers, was reported in the temperature range (293.16–333.16 K) and as a function of the concentrations (0.25×10−4 mmol/dm3 12.3×10−4 mmol/dm3). The free energy of dissociation ΔGdiss variation versus the neutralization degree shows the negative value due to the steric and electrostatic effect of the alkyl chains. The positive values of ΔH and ΔS confirmed the spontaneity and disorder of the reaction. The critical concentration C* of the two copolymers was determined from the enthalpy ΔH0 and entropy ΔS0 changes. The transition in conformation of the copolymer chains was influenced by the presence of hydrophobic-hydrophilic and hydrophobic-hydrophobic interactions.
Deposition of xylan isolated from Pennisetum purpureum on fibres of Eucalyptus globulus and characterisation of the composition of the surface xylans by immunolabelling and enzymatic peeling
Authors: Tamminen Tarja , Mikkelson Atte , Siika-aho Matti , Kruus Kristiina , Pere Jaakko , Borges Gomes Fernando José , Colodette Jorge Luiz 
Published: September 2018

Abstract
Adsorption of xylan on pulp is a potential method to improve its properties, especially refinability for high quality printing and writing (P&W) paper grades. In this study, elephant grass [Pennisetum purpureum (Schumach.)] xylan was used for this purpose. The xylan was extracted using cold caustic extraction (CCE) from P. purpureum brown pulp, produced by the Soda-AQ process (kappa 20). Xylan resorption was accomplished during the oxygen delignification phase of eucalypt [Eucalyptus globulus (Labill.)] pulp to avoid problems induced by the colour of the lignin-contaminated deposited xylan. Immunolabelling and enzymatic peeling methodologies were compared for the analysis of the spatial distribution of xylan in the fibre wall. The labelling appeared unevenly as faint and brighter patches on fibre surfaces. Increased labelling of xylan was detected on the samples with precipitated P. purpureum xylan. The enzymatic peeling method using a total hydrolysis enzyme mixture yielded a composition gradient as a function of time, showing clear xylose (Xyl) enrichment in the very beginning of the reaction, reflecting hydrolysis of fibre surfaces. Pure xylanase and endoglucanase hydrolyses yielded different product patterns and kinetics compared to total hydrolysis, but interpretation of those results in terms of xylan localisation was not straightforward.
Brønsted base mediated one-pot synthesis of catechol-ended amphiphilic polysarcosine-b-poly(N-butyl glycine) diblock copolypeptoids
Authors: Gebru Hailemariam , Wang Xin , Li Zhenjiang , Liu Jingjing , Xu Jiaxi , Wang Haixin , Xu Songquan , Wei Fulan , Zhu Hui , Guo Kai 
Published: September 2018

Abstract
Catechol moiety offers a versatile platform in the preparation of functionalized polymers, but it is not usually compatible with catalysis in polymerizations. To address these challenges, we suggest employment of one Brønsted base in masking the activity of catechol moiety and to modulate the polymerization. Based on this strategy, the ring-opening polymerization (ROP) of sarcosine N-carboxyanhydrides (Sar-NCA) was carried out using dopamine hydrochloride as an initiator and triethylamine as a Brønsted base. PSar with predicted molecular weights (M
n,NMR=3.7 kg mol−1) and narrow dispersities (Đ<1.13) was prepared. Catechol initiator was successfully linked to PSar end as confirmed by MALDI-ToF MS. Subsequently, copolymerization of N-butyl glycine N-carboxyanhydrides (Bu-Gly-NCA) from the PSar in one-pot produced catechol end-functionalized amphiphilic polysarcosine-block-poly(N-butyl glycine) diblock copolypeptoids (cat-PSar-b-PGlyBu). Further, cat-PSar-b-PGlyBu enabled the aqueous dispersion of manganese oxide nanoparticles which was attributable to the anchor of the diblock copolymers onto the surface of the nanoparticles. The strategy for catechol masking and polymerization mediating by one Brønsted base offered a new avenue into the synthesis of catechol-ended block copolymers.
The Ideological Malleability of Corruption. A Comparative Analysis of Official Corruption Discourses in Albania and Colombia, 2010-2017
Authors: Kajsiu Blendi 
Published: September 2018

Abstract
Corruption literature has paid little attention to the way corruption discourses reflect specific ideological agendas. This paper aims to address such shortcoming by comparing official corruption discourses in Albania and Colombia during the last seven years. The paper shows that despite similar levels of corruption, the leaders of the two countries articulate corruption in slightly different ways. While the prime minster of Albania Edi Rama articulates corruption narrowly as bribery, a phenomenon that pertains almost exclusively to the public sector, president Juan Manuel Santos of Colombia articulates it more broadly as a phenomenon that has moral, ethical and cultural dimensions, which can also originate in the private sector although more pervasive in the public one. Based on the findings of this paper, these divergent articulations reflect ideological variations between the two leaders more than different corruption ‘realities’ on the ground.
Turkeys Do Not Vote for Christmas. The Brazilian Anti-Vote-Buying Law
Authors: Carmo Andreia reis do 
Published: September 2018

Abstract
The research to date shows conflicting results about the effect of perceived corruption on political participation by the public. Corruption perception can mobilize, demobilize, or show no impact on political participation. The Brazilian Anti-Vote-Buying Law of 1999, one of the fastest laws ever to be approved in the country, is an example of how perceived corruption can increase public engagement. Using process tracing, the author tells this story identifying two sets of factors ranked according to their causal power (distal and proximal conditions) and further test the theory. The Brazilian population, who perceived corruption as high, learned about the antidemocratic aspects of vote buying and how to curb it. This ‘informed’ perception of corruption led people to politically participate by signing the popular initiative.
The Authorship of the Refutatio omnium haeresium
Authors: Cosentino Augusto 
Published: September 2018

Abstract
The Refutation of all heresies is a work that the manuscripts attributed to Origen. In the nineteenth century the attribution to Hippolytus was imposed, which was later called into question by several scholars since the mid-twentieth century. As yet there is no alternative attribution. This article attempts to focus on the status quaestionis, advancing some working hypotheses.
Morpho-syntactic variations in English and Spanish clipped words: a contrastive study
Authors: Rodríguez González Félix , Sánchez Fajardo José A. 
Published: September 2018

Abstract
Clipping and linguistic variation are inexorably interconnected. Shortened or elliptical words reflect a great deal of variability of the language, especially in the morphological and phonological levels. The object of this study is precisely to explore the phono-graphemic and grammatical variations occurred in the visible changes undergone by clipped words in Spanish and English. A contrastive analysis of this type reveals both expectedly different correspondences in terms of gender and number, and surprisingly parallel lexico-syntactic features. This suggests that clipped or elliptical units are not only necessarily dependent on intrinsic morpho-grammatical and phonological traits, but they are also characterized by regularities and universal patterns that might show disruptive or “corrupted” constructs. This analysis confirms the peculiarities of clipping and linguistic variations in both languages, in an attempt to comprehend the interconnection between functional motivations, and morphological and phonological changes.
«Por voloir castoier li coarz et li van»: lettura dell’Entrée d’Espagne
Authors: Galbiati Roberto 
Published: September 2018

Abstract
The anonymous Padovano, author of the Entrée d’Espagne, writes to admonish and educate the knights and the rulers of his time: his explicit aim is to «castoier li coarz et li van». Therefore, it is not surprising that the story of the chanson is provided with a moral intent. The knights of the Entrée often disobey Charlemagne’s orders because of their pride and wrath. Also Roland, the best Christian knight, is affected by these vices, as the episode of the conquest of Nobles shows. His adventure in the Orient can be read as a penitential route, at the end of which he learns the high value of humility. Given the moral goal of the text, the author proposes to date the Entrée in the early decades of the fourteenth century (between 1312 and 1328), when the Paduan commune and the Trevisan March were upset by civil wars, determined by the violence and the vicious ambitions of the local nobility.
La nave di Folco
Authors: Gambino Francesca 
Published: September 2018

Abstract

Foucon de Candie is an epic poem dating to the last two decades of the twelfth century. In the first part, it tells the story of Foucon, one of Charlemagne’s nephews, acquiring the Saracen city of Candie. The still unpublished Franco-Italian version of this chanson de geste contains some laisses that are not in the rest of the French tradition. In this article I publish and comment on two of them which describe the galley of Foucon (La nef Folcho mult est bien atorné e Per gran maistrixie hont afermé un doion).
La Producción Científica en Ciencias de la Salud ¿Un asunto de cantidad o calidad?
Authors: Borré-Ortiz Yeis Miguel 
Published: September 2018

El fenómeno de la globalización ha sido un proceso de grandes cambios y profundas transformaciones en todos los sectores a nivel mundial, dichas transformaciones han permeado el ámbito de la educación superior de forma vertiginosa, y su impacto ha sido evidente. Las Instituciones de Educación Superior (IES), además de asumir el reto de formar recurso humano profesional, idóneo y competente para la sociedad. Considerando el panorama mundial, es inevitable saber que el área de las ciencias de la salud no es ajena a esta situación, debido a que cada vez más se vislumbra un cúmulo de publicaciones de diversa índole; desde algunas profesiones más que en otras, pero el fenómeno es evidente. Sin embargo, en los países en vías de desarrollo, se suele observar una paradoja que es importante resaltar, y es que mientras en las instituciones de educación superior existe un esmero por la producción de nuevo conocimiento, las instituciones de salud han sido lentas en su utilización y aprovechamiento para el mejoramiento de los procesos y resultados asistenciales. La actual situación con relación al esmerado interés en la producción científica a grandes cantidades ha generado muchos sesgos en la calidad de las mismas.