bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assesment of nurses knowledge about non – Hodgkin’s lymphomas
Authors: Kurek Magdalena , Tatara Tomasz 
Published: May 2018

Abstract

Introduction. Non-Hodgkin lymphomas (NHL) are among the most frequent types of cancer linked with the lymphatic system. The disease, if not diagnosed or treated, may lead to serious health complications and/or death.

Aim. The purpose of the work is to evaluate the level of knowledge of nursing staff about NHL.

Material and methods. There were 100 members of nursing staff aged from 24 to 56 participating in the study. The research method was a diagnostic survey but the measuring tool was an anonymous author’s questionnaire which comprised 25 closed, single-choice questions and 2 filtering questions.

Results. Among the respondents, 48% work at the Clinical Haematology/Oncology Ward, while the remaining 52% work in other wards. The question: “Is it possible for the NHL to be located outside the lymphatic system?”, 55% of respondents responded with an affirmative, 23% with a negative, 22% did not know the answer. Among the respondents, 100% stated that their employers do not designate any financial assets to train medical personnel with respect to expanding their knowledge about non-Hodgkin lymphomas. As many as 46% of respondents expand their knowledge through self-study using their own means. According to the National Cancer Registry, in 2014 there were 874 incidents and 236 deaths noted among men and 862 incidents and 235 deaths among women, linked with the diffused NHL. Comparing the data of the National Cancer Registry with the previous years, we can observe an increasing trend of morbidity and mortality, linked with the NHL. For example, in 2006 there were a total 1207 cases and 315 deaths linked with the diffused NHL.

Conclusions. Results show that the respondents’ awareness with regard to NHL is limited. Employers do not finance NHL training, which may affect the low level of knowledge. NHL patient hospitalization is a long-term process requiring expenses and effort on the side of medical personnel. Nursing and health education are necessary elements of the therapeutic process of an NHL patient.
Providing help to multicultural patients in the context of contemporary population migrations in Europe
Authors: Kiszka Jerzy , Ozga Dorota , Mach Arkadiusz , Krajewski Romuald 
Published: May 2018

Abstract

Introduction. The population migration to the countries of the European Union (EU) of the conflict of war has grown substantially in recent years. According to the Office for Foreigners in Poland are staying 586 thousand foreigners. 279 refugees from Syria arrived in Poland in 2015. The economic development of Poland means that the number of foreigners settling in or crossing Poland and using the services of the Polish health service is constantly growing. Foreigners from outside Europe (the largest groups are Vietnamese – 8.8 thousand and Chinese – 6.2 thousand) were brought up in a different culture, but also people from European countries (the largest group are immigrants from Ukraine – 513 thousand) may differ from Poles perceive health and illness. Health Personnel may encounter difficulties in providing medical assistance and taking care of a culturally different patient. They may result from the language barrier, lack of knowledge about the differences in patients’ expectations or lack of skills in communication with the patient. The result may be improper assistance, violation of patients’ rights and avoiding the use of medical services.

Aim. Presentation of the migration of population in EU countries, analysis of problems arising during the provision of assistance to culturally different patients and an indication of the possibility of developing cultural competences of paramedics, nurses and doctors through education in this area.
An image of nurses and nursing in Poland in the media and in the opinion of various social groups. Systematic review of scientific literature from the years 2010-2017
Authors: Machul Michał , Chrzan-Rodak Agnieszka , Bieniak Monika , Bąk Jadwiga , Chałdaś-Majdańska Justyna , Dobrowolska Beata 
Published: May 2018

Abstract

Introduction. Nursing is a profession of public trust with a fairly high position in various rankings examining the prestige of professions.

Aim. Analysis of published research results on the image of nurses and nursing in Poland in the media and in the opinion of various social groups.

Material and methods. A systematic review of Polish scientific literature from the years 2010-2017 was undertaken. A multi-stage search process was carried out in accordance with the adopted inclusion criteria, and then articles identified and accepted were subjected to a qualitative analysis.

Results. Searching the Google Scholar database by accepted key words resulted in 10,663 records. After analyzing the titles and abstracts of these papers, 19 articles were subjected to further analysis. As a result of searching journals included in the Arianta database according to established key words, 10 articles were identified, 8 of which were qualified for further analysis. After removing duplicates, 17 articles were approved for the final analysis. Qualitative analysis of the research results published in these papers allowed to distinguish the following categories: an image of nurses and nursing in various social groups, elements of nurses’ image in the media and society, actions aiming at improving the image of nurses and nursing in Poland, changes in the image of nurses and nursing in Poland over the years and the direction of these changes.

Conclusions. The issue of an image of nurses and nursing in the media and in the society has been a frequent subject of research of nurses in Poland in the recent years. These studies concern primarily opinions on the image of nurses and nursing, factors which determine the image of nurses and nursing in Poland, constitutive elements of the image, the possibility of improving the image and people/ institutions responsible for it.
The inhibitors – a challenge for the management of patients with hereditary haemophilia A
Authors: Mihăilă Romeo-Gabriel 
Published: May 2018

Abstract

Introduction. Our research strategy was aimed at evaluating the possible implication of the type of factor VIII product administered as substitution treatment to haemophilia A patients in the occurrence of inhibitors and their consequences on the management.

Methods. Scientific articles from July 2015 to July 2017 were searched using the PubMed and PubMed Central databases. The used search terms included “haemophilia A”, “inhibitors”, “plasma-derived factor VIII” and “recombinant factor VIII”.

Results. The risk factors for inhibitors occurrence may be patients-related (genetic and nongenetic) and treatment-related. The possibility of a correlation between the increased purity of factor VIII given as substitution treatment and the occurrence of inhibitors is discussed in the light of literature data. Plasma-derived factor VIII is less immunogenic, but not entirely safe from the point of view of the possibility of transmitting biological agents. It is obvious that there is not enough plasma-derived factor VIII for the planet’s needs. Recombinant factor VIII products have revolutionized the treatment of patients with haemophilia A over the past 3 decades by the disappearance of transfusion-related infections and their complications. They are safer in terms of pathogens and the new long-acting factor VIII products are based on recombinant DNA technology.

Conclusion. Plasma-derived or recombinant factor VIII products must co-exist on the market for the benefit of haemophilic patients. Future solutions could be: less immunogenic factor VIII products, nonfactor replacement strategies, or bispecific antibody that mimics the function of coagulation factor VIII.
Malignancy in a retrospective cohort of 17 patients with Dermatomyositis or Polymyositis in southern Tunisia
Authors: Sellami Khadija , Mseddi Madiha , Snoussi Mouna , Gharbi Hela , Frikha Faten , Salah Rayda Ben , Jallouli Moez , Marzouk Sameh , Masmoudi Abderrahmen , Bahloul Zouhir , Turki Hamida 
Published: May 2018

Abstract
Introduction. The prognosis of dermatomyositis (DM)/ polymyositis (PM) in adults is partly related to their association with neoplasia. The aim of our study was to report the epidemiologic, clinical, paraclinical, therapeutic and evolutionary aspects of DM associated with malignancy in patients from Sfax, south eastern of Tunisia. Methods. A retrospective cohort study of patients with DM or PM admitted in Dermatology and Internal Medicine Departments of Hedi Chaker University Hospital of Sfax between 1996 and 2015. Cases of DM or PM associated with malignancy were retained. Results. Seventeen cases (13.5%) of DM or PM associated with malignancy were noted. Fourteen patients had DM and 3 patients had PM. The Sex ratio M / F was 0.3 and the mean age at diagnosis was 56.5 years. In DM patients, malignancy preceded the myositis in 64.2% of cases. In PM patients, only one patient was known to have breast cancer and the myositis revealed the cancer for 2 others. Treatment consisted of corticosteroids associated with methotrexate in 4 cases. Outcome was fatal in 5 cases (29.4%), due to the underlying cancer in 3 cases. Swallowing disorders related to DM/PM were responsible for death in 2 cases. Conclusion. There are no specific clinical or biological features in paraneoplastic DM. In our series, breast neoplasm represented the first cancer associated with DM. Cancers of nasopharynx, colon and urinary tract had the second position.
Multiple Metastases Gestational Choriocarcinoma - A Case Report
Authors: Mehedințu C. , Cîrstoiu M.M. , Brătilă E. , Plotogea M. , Antonovici M. , Cazachevici A. , Berceanu C. 
Published: May 2018

Abstract
Introduction. Gestational choriocarcinoma (GC) is a malignant condition that develops form trophoblastic cells originating from a previous pregnancy, eutopic or ectopic. Metastatic choriocarcinoma is often diagnosed in the absence of a primary uterine or ovarian tumor, presumably because the latter has undergone complete necrosis. GC rapidly metastasizes spreading to lungs, brain, bones, bone marrow, liver, and other organs, but responds well to chemotherapy. Material and methods. We present the case of a 25-year-old woman with critical evolution after being diagnosed with choriocarcinoma following a complete hydatidiform mole pregnancy. Even though the patient initially received proper treatment, due to poor follow-up compliance, the condition led to invasive metastases. When it spread to the musculoskeletal system and other organs, doctors were able to link symptoms to the choriocarcinoma diagnosis and chemotherapy was initiated. Unfortunately, the patient succumbed due to intracranial hemorrhage. Discussions. GC is a highly and fast invasive malignancy, with rapidly growing tumors. It is often associated with hemorrhage, ischemic necrosis, and secondary inflammation. Often, by the time the tumor is discovered, X-rays of the chest and bones already show metastatic lesions. Chemotherapy success depends on early detection and diagnosis of tumors after pregnancy. Conclusions. Even though the initial diagnosis and treatment should have led to a favorable outcome, the patient’s poor compliance was followed by rapid progression of the disease and, finally, exitus.
Multidisciplinary Treatment of Voluminous Pelvic Tumor With Gluteal Development - Case Presentation
Authors: Brătilă E. , Cârstoiu C. , Comandaşu D.E. 
Published: May 2018

Abstract
The aim of the paper was to present the case of a 64-year-old patient with no significant pathological history, accusing the significant increase in volume of her left buttock, accompanied by sciatic compression and pelvic pain phenomena. Clinical evaluation revealed a large, left gluteal tumor, of regular shape and medium consistency, painless at palpation, causing hyperesthesia in the sciatic territory by compression. The IRM with contrast enhancement described a heterogeneous tumor, measuring about 25 centimeters in diameter, isointense in the T1 and T2 signals, with hypointense areas and imagistic aspect suggesting differential diagnosis between liposarcoma and fibrolipoma. From the imagistic point of view, the origin of the tumor was pelvic, with a threadlike tract in the sciatic hole and development in the gluteal region for the most part. Surgery was decided on a multidisciplinary team including a gynecologist, orthopaedist, and general surgeon, using a double approach through laparotomy and gluteal incision. The first operative step consisted in laparotomy with pelvic tumor dissection at the level of the iliac vessels and its prolongation at the level of the sciatic hole. The large gluteal incision was used during the second step in order to mobilize the tumor form between the gluteal fibers. Subsequent thorough hemostasis was performed with postoperative aspect inspection through both approaches. The postoperative evolution was favorable without immediate or late complications. The histopathological result was fibrolipoma, with good prognosis for the patient. In conclusion, the multidisciplinary surgical approach in this patient presenting with a pelvic tumor with transischial gluteal development was the optimal choice, which led to a favorable outcome in a complex case.
Statistically Based Survival Rate Estimation in Patients with Soft Tissue Tumors
Authors: Şerban B. , Panti Z. , Nica M. , Pleniceanu M. , Popa M. , Ene R. , Cîrstoiu C. 
Published: May 2018

Abstract
Introduction. Although most soft tissue tumors are benign, with a high healing rate after surgical excision, there is a variety of malignant tumors with differences in progression and prognosis. The study aims to assess the survival rate in patients diagnosed with this pathology, based on the patient’s characteristics (age, gender, race), as well as the tumor’s (histological type, differentiation degree, location and size). Materials and methods. The retrospective study included a group of 103 patients diagnosed in our department during 2010 and 2017. Considering the high healing rate of benign tumors, only the group of neoplastic patients (45 cases) was involved in the survival rate estimation, assessing tumor characteristics and individual comorbidities. Within this lot, we emphasized a predominance of neoplasm in patients aged over 50 years (32 cases), men (29 cases), and localization of the neoplasm in the thigh (23 cases). The predominant histopathological type, liposarcoma, was diagnosed in 67% of the cases, with dimensions over 6 cm and with local extension. Results. There have been significant variations in mortality between the different histological subtypes (liposarcoma vs. synovial sarcoma). Local recurrences were shown in 18 cases of liposarcoma in the first 2 years after the surgical excision, with an increased aggressiveness of this neoplasm in men over 50 years. 12 cases developed distant metastasis, and, until the end of the study, 7 deaths were reported in 3 cases involving associated comorbidities. Conclusions. The five-year survival is inversely proportional to the extent of the tumor and the local invasion, as well as to the age of the patient. It is difficult to appreciate an overall survival rate in the context of a heterogeneous group of tumors so it must be evaluated for every histological subtype taking into account the patient’s particularities.
Femoral Giant Cell Tumor in a Patient with Surgically Treated Femoral Condyle Fracture: Misdiagnosis or Coincidence?
Authors: Japie I.M. , Bădilă A. , Ciobanu T. , Manolescu R. , Rădulescu D. , Japie E.M. , Bujdei A. , Cîrstoiu C. 
Published: May 2018

Abstract
Introduction. Giant-cell tumor of bone (GCTB) is a benign tumor with an unpredictable evolution, representing 4-5% of all primary bone tumors and 15% of benign bone tumors usually affecting 20-45 years old adults. The predilect location is the distal femur, proximal tibia, and distal radius. Case presentation. We report the case of a 31-year-old male, regardless of medical history, admitted in the emergency department (ED) for significant pain and functional impairment of the right knee, after suffering a traumatic event. Clinical examination and imaging tests established the diagnosis of lateral femoral condyle fracture. Therefore, osteosynthesis with 4 screws was performed. Postoperative evolution was uneventful until one year later when the patient presented to the ED for pain and inflammatory aspect of the right knee, but with no history of trauma during this time. The imagistic exams of the right knee (X-ray, magnetic resonance imaging and scintigraphy) detected a tumor of the lateral femoral condyle that also affected the osteosynthesis material. Thus, the removal of screws and histopathological exam were performed, the latter establishing the diagnosis of GCTB. Taking into consideration radiological and histological aspects of the tumor and relating them to the clinical findings, the GCTB was classified in stage III Enneking. The patient underwent surgery, segmental resection of the tumor in oncological limits and arthroplasty with modular tumoral prosthesis was performed. Postoperative results at 6 and 12 months according to Musculoskeletal Tumor Society Scoring System were very good. The key feature of this case consists of post-osteosynthesis appearance of the GCTB given the fact that only 3 cases of GCTB affecting the screw site were reported in literature.
Modular Reconstruction Systems – Final Solution for Critical Bone Defects Treatment
Authors: Nica M. , Ene R. , Panti Z. , Popa M. , Pleniceanu M. , Cîrstoiu M.M. , Cîrstoiu C. 
Published: May 2018

Abstract
Introduction. The management of critical bone defects has experienced an unprecedented improvement in the last few decades. A good primary mechanical stability and versatility of the modular reconstruction systems allowed the conversion to universal setups and the expansion of indication. The progression and reliability of the reconstruction possibilities available nowadays are outlined using the experience of our department. Material and method. A retrospective review of critical bone defect cases and the reconstruction management using endoprosthetic systems is presented. Ten reconstruction surgeries performed in the last 18 months in our department were observed. The patients were 3 males and 7 females with a mean age of 45.3 (range 19 to 75). Modular systems were used for the reconstruction of bone defects subsequent to resections of benign or malignant musculoskeletal tumors (76%) and to non-neoplastic conditions (24%). Results. On the latest follow-up, all the patients were alive, with one case of tumoral recurrence. No aseptic loosening, soft tissue or structural failure were recorded following surgery, with one case under treatment for infection after it required an open procedure for a prosthetic hip dislocation. The early functional results were adequate in all cases, with good secondary stability and satisfactory quality of life. Conclusion. The evolution of endoprosthetic reconstruction surgery has improved the prognosis for many patients diagnosed with critical bone defects. Continuous advances in implant design, fixation, and soft tissue attachment combined with the improvement of surgical techniques will ensure a bright future for this type of procedures.
Femur Metastasis Secondary to a Carcinoma of the Uterine Cervix (Case Study)
Authors: Popescu D. , Panaitescu C. , Nedelcu R. , Trifu Şt. , Cîrstoiu C. 
Published: May 2018

Abstract
Purpose. The purpose of this study is to correlate the existence of a unique bone metastasis of the femur, secondary to a carcinoma of the uterine cervix, the treatment plan, and the recovery of the patient. Materials and method. From previous studies, it is known that the prevalence of unique bone metastasis of the femur secondary to carcinoma of the uterine cervix is very low, in most cases the patients having multiple metastases or in other organs. The case presents a 40-year-old patient who had surgery 2 years before for a carcinoma of the uterine cervix. After the surgical treatment, the patient received chemotherapy and radiotherapy. Nowadays, the patient exhibits pain in the left hip. Following the clinical and paraclinical protocols, an incisional biopsy was made. The histopathologic result was metastasis from the uterine cervix squamous cell carcinoma. The surgical treatment consists of segmentary resection and total hip arthroplasty with tumor reconstruction prosthesis. Results. After total hip arthroplasty with tumor reconstruction prosthesis, we were able to make a segmentary resection in oncological limits, with the complete excision of the metastasis, the patient being able to start the recovery the next day after the surgery. Conclusions. As a surgical indication, the tumor prosthesis represents the best option in the segmentary resections of tumors, this allowing a reconstruction and an early recovery.
Scapular Metastasis by Rcc. Case Presentation
Authors: Nicula A.I. , Marinescu A. , Iana G. 
Published: May 2018

Abstract
Bony metastasis is a frequent occurrence in malignancies. We present the case of a 75-year-old male patient who was investigated for a lytic lesion in the right scapula and was eventually diagnosed with metastatic renal cell carcinoma (RCC). The main indications for embolization are reducing the risk of bleeding during and after surgery of hypervascular tumors, simplifying the manipulation of tumors, palliation of pain, bleeding, fever, and hypercalcemia-like symptoms in inoperable tumors, preventing further dissemination of a tumor, and increasing the response to chemotherapy and radiotherapy. Embolization may be a therapeutic alternative to surgery in cases in which surgery is inappropriate or associated with high risk. In the case presented, CT examinations had a crucial role both in the diagnostic orientation and in the subsequent therapeutic decisions and proper monitoring under therapy.
Conventional Radiography and MRI Diagnosis of Bone Tumors Developed at the Knee
Authors: Codorean I. , Codorean I.B. 
Published: May 2018

Abstract
Introduction. It is known that bone tumors have a predilection to develop for a certain skeletal bone segment. Also, bone tumors have a predilection for certain age groups. The knee is a common site for bone tumors. Purpose. Presentation of diagnostic parameters of conventional radiography as the first technique in the detection and characterization of bone tumors developed at the knee level and the criteria for differentiation of the malignant substrate from the benign (the type of bone destruction, the type of periosteal response, poorly defined margins) one. The value of MRI is also presented and illustrated as a unique imaging technique that allows the direct visualization of bone marrow with high spatial resolution for local staging of bone tumors. Material and method. The present study aimed to investigate the radiographic and MRI imaging characteristics of bone tumors developed at the knee joint, which were retrospectively analyzed (October 2007 and November 2017) in a selected group of 91 patients. The limit of age between 11 and 67 years, 73(70%) men, 18 (30%) women. Examination protocol: complete clinical examination, radiographic knee examination in anteroposterior and lateral incidents. MRI standard protocol, native, and post paramagnetic contrast. Results. Conventional Radiographic and MRI have been detected and characterized a number of 55 (67%) primary malignant bone tumors confirmed by histopathological diagnosis, ranging from 8 histopathological types and 37 (33%) cases of benign tumors with 9 histopathological types. Conclusions. Radiological examination is the first investigation in the evaluation of knee bone tumors, suggesting the malignant nature expressed by the badly defined margin, bone destruction, discontinuous peristaltic reaction, and extension to the soft parts. MRI is a unique imaging technique that allows direct visualization of bone marrow with high spatial resolution and best tool for local staging of bone tumors.