bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Social Support Networks on Family Resilience in an Australian Intensive Care Unit: A Constructivist Grounded Theory
Authors: Wong Pauline , Liamputtong Pranee , Koch Susan , Rawson Helen 
Published: November 2018

AbstractPurposeThis article discusses the findings of a grounded theory of family resilience in an Australian intensive care unit (ICU) with a specific focus on families’ experiences of their interactions with other members within their own family, and the families of other patients in the ICU.DesignA constructivist grounded theory methodology was adopted. Data were collected using in‐depth interviews with 25 family members of 21 critically ill patients admitted to a tertiary‐level ICU in Australia.FindingsThe core category regaining control represents the families’ journey toward resilience when in ICU. The major categories represent facilitators for, and barriers to, regaining control. One of the main facilitators is drawing strength, and it explains the manner with which families receive social support from their own and other family members to help them cope.ConclusionsThis study offers a framework to improve patient‐ and family‐centered care in the ICU by facilitating families’ ability to manage their situation more effectively. Social support offered by family members facilitates the families’ ability to regain control. An ICU family resilience theoretical framework, situated within the context of the Australian healthcare system, adds to what is currently known about the families’ experiences in the ICU.Clinical RelevanceThe relationships that develop between families in the ICU may provide a source of social support; however, not all families welcome interactions with other ICU families, and it may cause further emotional distress. Further research is warranted to determine whether families suffer a secondary stress reaction from incidental interactions with other patients’ families in the ICU. Furthermore, when family members pull together and offer social support to each other, they are better able to regain control. This process contributes to an ICU family resilience framework.
The mediating role of sleep in the relationship between Indigenous status and body mass index in Australian school‐aged children
Authors: Deacon‐Crouch Melissa , Begg Stephen , Tucci Joseph , Skinner Isabelle , Skinner Timothy 
Published: November 2018

AimAssociations between sleep duration and obesity and between obesity and chronic illness are established. Current rates of obesity for all Australian people are rising. Recent reports indicate that high body mass index (BMI) is a leading contributor to overall burden of disease for Indigenous Australians. Understanding the factors that contribute to higher rates of obesity in Indigenous people is critical to developing effective interventions for reducing morbidity and premature mortality in this population. To explore the effect of sleep duration on the relationship between Indigenous status and BMI in Australian children.Methods716 non‐Indigenous and 186 Indigenous children aged 5–12 years in the Australian Health Survey 2011–2013. Primary carers were interviewed regarding children's sleep times; BMI was derived from measurement.ResultsAnalysis of covariance revealed that regardless of a number of demographic and socio‐economic status markers, sleep duration and Indigenous status were independent predictors of BMI. However when both predictors were considered together, only sleep duration remained predictive of BMI.ConclusionsSleep duration plays an important mediating role in the relationship between Indigenous status and BMI in this Australian sample. Modification of sleep duration for Indigenous children may lead to longer‐term positive health outcomes.
Identification and characteristics of Stagonosporopsis cucurbitacearum pathogenic factors influencing pumpkin seeding survival in north‐east China
Authors: Zhao Qian , Wu Jianzhong , Zhang Liyan , Xu Lizhen , Yan Chao , Gong Zhenping 
Published: November 2018

AbstractThe parasitic pathogenic fungus Stagonosporopsis cucurbitacearum (Sc.) is the main cause of pumpkin gummy stem blight (GSB), one of the most devastating pumpkin crop diseases in north‐east China. In the present study, transcriptome analyses of the GSB‐susceptible strain commonly grown in that region, zq‐1, were performed to identify differentially expressed genes (DEGs) relevant to GSB infection. Using RNA‐seq of six fungal samples, we obtained 44.62 Gb of clean sequence data with a Q30 base percentage of 92.38% or higher. We carried out functional annotation by comparing sequences against NR, Swiss‐Prot, KEGG, COG, KOG, GO, and Pfam databases and obtained annotation results for 38,110 unigenes. From these unigenes, a total of 341 DEGs were identified and subjected to GO functional annotation and KEGG pathway analysis. Subsequently, 52 genes possessed putative pathogenic functions, with 34 genes assigned to molecular function (including hydrolase, protein kinase, phosphatase, cellulase, etc.), 15 genes assigned to biological process, and 3 genes assigned to mitogen‐activated protein kinase pathways, ABC transport proteins and cellular endocytosis. Identification of DEGs should enhance our understanding of pathogenic genes involved in pumpkin infection by Sc. and should facilitate the systematic investigation of pathogenic gene expression patterns and host–pathogen interactions.
Phylogenetics of Annona cherimola (Annonaceae) and some of its closest relatives
Authors: Larranaga Nerea , Albertazzi Federico J. , Hormaza Jose I. 
Published: November 2018

AbstractAnnona cherimola is a woody perennial species in the Annonaceae family that produces edible fruits and has economic importance in several regions of the world with subtropical climates. Together with other 10‐12 species, A. cherimola belongs to the section Atta of the Annona genus with a center of origin in Central America and the Caribbean. Species of the section Atta produce soft skin ripe fruits with raised areoles bounded by recessed furrows. Annona cherimola is the only species of the section naturally found in the Andean region of South America. Currently, no information is available at the molecular level on the phylogenetic relationships of most of the species of Atta and closely related sections in Annona. In order to fill this gap, in this work a phylogenetic approach was performed using five coding and non‐coding plastid DNA regions, to determine the phylogenetic relationships between A. cherimola and other related species included in Atta and other sections of the genus. The results obtained support recent studies that demonstrated the likely Mesoamerican origin of A. cherimola based on biogeographical analysis with SSR markers, rather than the previously considered South American origin hypothesis. In addition, the species belonging to the Atta section did not show monophyly. Finally, A. cherimola and A. pruinosa seem to be phylogenetically close species and additional studies are needed to discern the relations between them.
Association of HLA‐DPA1 and HLA‐DPB1 polymorphisms with spontaneous HBsAg seroclearance in Caucasians
Authors: Koukoulioti Eleni , Fischer Janett , Schott Eckart , Fülöp Balazs , Heyne Renate , Berg Thomas , van Bömmel Florian 
Published: November 2018

AbstractBackground & AimsAcute hepatitis B virus (HBV) infections may clear spontaneously or become chronic and run through different phases. The single nucleotide polymorphisms (SNPs) rs3077, rs9277535 and rs9277534 within the human leucocyte antigen (HLA)‐DP gene have been found to be associated with HBV susceptibility and persistence in Asians. However, evidence for the influence of these variants in Caucasians has been limited so far. The aim of our study was to investigate the impact of these polymorphisms on the outcome of HBV infections in a large Caucasian population.MethodsIn this case‐control study, we retrospectively analysed 1111 Caucasian individuals, including 618 with chronic HBV infections (CHB), 239 with spontaneous HBsAg seroclearance (SC) and 254 healthy controls (HC). The rs3077, rs9277535 and rs9277534 SNPs were genotyped by a polymerase chain reaction from blood samples and melting curve analysis.ResultsA significant difference in the allele distributions was observed only for the rs3077 SNP between the HC and the CHB group as well as between the SC and CHB groups. The rs3077‐C allele was associated with a lower probability for spontaneous HBsAg seroclearance in comparison with the rs3077‐T allele (OR 0.704, 95% CI 0.509‐0.974; P = 0.033). No association of the three SNPs with the stages of chronic HBV infection was found.ConclusionThis is the first study demonstrating an association of the rs3077‐T allele with spontaneous HBsAg seroclearance in Caucasians. Further studies are needed to elucidate the role of HLA‐DP variants in disease pathogenesis and their potential role for individualized disease management.
The role of culture in language and cognition
Authors: Everett Daniel L. 
Published: November 2018

AbstractThis paper provides an overview of some recent research on how culture is causally implicated in the understanding of human cognition. In particular, I review studies on the influence of culture on short‐term memory, visual perception, grammar, numerical cognition, and language evolution. I also provide a list of desiderata for research methodologies on the connections between culture and cognition and a direction for future research.
Skeletal muscle performance in metabolic disease: Microvascular or mitochondrial limitation or both?
Authors: Frisbee Jefferson C. , Lewis Matthew T. , Wiseman Robert W. 
Published: November 2018

AbstractOne of the clearly established health outcomes associated with chronic metabolic diseases (eg, type II diabetes mellitus) is that the ability of skeletal muscle to maintain contractile performance during periods of elevated metabolic demand is compromised as compared to the fatigue‐resistance of muscle under normal, healthy conditions. While there has been extensive effort dedicated to determining the major factors that contribute to the compromised performance of skeletal muscle with chronic metabolic disease, the extent to which this poor outcome reflects a dysfunctional state of the microcirculation, where the delivery and distribution of metabolic substrates can be impaired, versus derangements to normal metabolic processes and mitochondrial function, versus a combination of the two, represents an area of considerable unknown. The purpose of this manuscript is to present some of the current concepts for dysfunction to both the microcirculation of skeletal muscle as well as to mitochondrial metabolism under these conditions, such that these diverse issues can be merged into an integrated framework for future investigation. Based on an interpretation of the current literature, it may be hypothesized that the primary site of dysfunction with earlier stages of metabolic disease may lie at the level of the vasculature, rather than at the level of the mitochondria.
Identification and characterization of the rice pre‐harvest sprouting mutants involved in molybdenum cofactor biosynthesis
Authors: Liu Xin , Wang Jing , Yu Yang , Kong Lina , Liu Yimei , Liu Zhiqi , Li Hongyu , Wei Piwei , Liu Minglong , Zhou Hai , Bu Qingyun , Fang Jun 
Published: November 2018

Summary

In cereal crops, ABA deficiency during seed maturation phase causes pre‐harvest sprouting (PHS), and molybdenum cofactor (MoCo) is required for ABA biosynthesis.

Here, two rice PHS mutants F254 and F5‐1 were characterized. In addition to the PHS, these mutants showed pleiotropic phenotypes such as twisting and slender leaves, and then died when the seedling developed to four or five leaves. Map‐based cloning showed that OsCNX6 and OsCNX1 encoding homologs of MoaE and MoeA were responsible for F254 and F5‐1 mutants, respectively. Genetic complementation indicated that OsCNX6 not only rescued the PHS and seedling lethal phenotype of the cnx6 mutant, but also recovered the MoCo‐dependent enzyme activities such as xanthine dehydrogenase (XDH), aldehyde oxidase (AO), nitrate reductase (NR) and sulfite oxidase (SO).

Expression pattern showed that OsCNX6 was richly expressed in seed during embryo maturation by quantitative reverse transcriptase PCR and RNA in situ hybridization. Furthermore, the OsCNX6 overexpression plants can significantly enhance the MoCo‐dependent enzyme activities, and improved the osmotic and salt stress tolerance without unfavorable phenotypes.

Collectively, these data indicated that OsCNX6 participated in MoCo biosynthesis, and is essential for rice development, especially for seed dormancy and germination, and OsCNX6 could be an effective target for improving abiotic stress tolerance in rice.
Updating the Chemiluminescence Oxygen‐Aftereffect Method for Determining the Rate Constant of the Peroxy‐Radical Self‐Reaction: Oxidation of Cyclohexene
Authors: Fedorova Galina F. , Lapina Viktoryia A. , Menshov Valery A. , Naumov Vladimir V. , Trofimov Aleksei V. , Tsaplev Yury B. , Vasil'ev Rostislav F. , Yablonskaya Olga I. 
Published: November 2018

AbstractUpdating the facile chemiluminescence oxygen‐aftereffect method, most suitable for determining the rate constant (kt) of the peroxy‐radical self‐reaction (main chemiluminescence channel), pertained to considering the sensitivity of such a method toward a disturbing influence of the peroxy radicals of the initiator of the chain oxidation process. Such a disturbance may derive from the side chemiluminescent reaction, which involves peroxy radicals of both hydrocarbon and initiator. To examine the applicability and limitations of the chemiluminescence method under present scrutiny, cyclohexene was used as the model oxidizable hydrocarbon substrate. Computer simulations of the reaction and chemiluminescence kinetics have demonstrated the validity of the considered methodology at the value of the rate constant of the propagation of the overall chain process by peroxy radicals of the initiator higher than 1 m−1 s−1. Despite that the chemiluminescence time profile and the stationary level of the total chemiluminescence intensity depend on the kinetics of the side chemiluminescence channel and on the ratio of the excited‐state generation yields in the mentioned reaction channel and in the main chemiluminescence process, the value of kt assessed by the oxygen‐aftereffect method has been found independent of variation of these characteristics.
Sleep disordered breathing in children disrupts the maturation of autonomic control of heart rate and its association with cerebral oxygenation
Authors: Walter Lisa M , Tamanyan Knarik , Weichard Aidan J , Davey Margot J , Nixon Gillian M , Horne Rosemary S. C. 
Published: November 2018

Key points
Sleep disordered breathing (SDB) affects 4–11% of children and is associated with adverse neurocognitive, behavioural and cardiovascular outcomes, including reduced autonomic control.
The relationship between heart rate variability (HRV; a measure of autonomic control) and age found in non‐snoring control children was absent during sleep in children with SDB.
Age significantly predicted increasing cerebral oxygenation during wake in non‐snoring control children, whereas during sleep, HRV significantly predicted decreasing cerebral oxygenation.
Cerebral oxygenation was not associated with either age or HRV in children with SDB during both wake and sleep.
SDB significantly disrupts the normal maturation of autonomic control and the positive association between autonomic control and cerebral oxygenation found in non‐snoring children, and we speculate that the dampened autonomic control exhibited by children with SDB may have an attenuating effect on cerebral autoregulation via the moderating influence of HRV on cerebral blood flow.
AbstractThe repetitive episodes of hypoxia that are features of sleep disordered breathing (SDB) in children are associated with alterations in autonomic control of heart rate in an age‐dependent manner. We aimed to relate heart rate variability (HRV) parameters to age and measures of cerebral oxygenation in children (3–12 years old) with SDB and non‐snoring controls. Children (SDB, n = 117; controls, n = 42; 3–12 years) underwent overnight polysomnography. Total (TP), low‐ (LF) and high‐frequency (HF) power, tissue oxygenation index (TOI) and fractional tissue oxygen extraction (FTOE) were analysed during wake and sleep. Pearson's correlations determined the association between age and HRV parameters, and multiple linear regressions between HRV, age and cerebral oxygenation parameters. During wake, age had a positive association with LF power, reflecting increased parasympathetic and sympathetic activity with increasing age for both control and SDB groups. This association was also evident during sleep in controls, but was absent in children with SDB. In controls, during wake TOI had a positive, and FTOE a negative association with age. During sleep, TP, LF and HF power were significant, negative determinants of TOI and positive determinants of FTOE. These associations were not seen in children with SDB during wake or sleep. SDB disrupts the normal maturation of the autonomic control of heart rate and the association between HRV and cerebral oxygenation exhibited by non‐snoring control children of primary school age. These results highlight the impact SDB has on cardiovascular control and the potential impact on adverse cardiovascular outcomes.
Resenha de 'A Nova Razão do Mundo: ensaio sobre a sociedade neoliberal', de Pierre Dardot e Christian Laval
Authors: Borges Samuel Silva 
Published: November 2018

Referência completa: Dardot, Pierre; Laval, Christian. A Nova Razão do Mundo: Ensaio sobre a sociedade neoliberal. São Paulo: Editora Boitempo, 2016 [2009].
Livro de Isaac: edição crítica da tradução medieval portuguesa da obra de Isaac de Nínive
Authors: Fachin Phablo Roberto Marchis 
Published: November 2018

O estudo realizado por César Nardelli Cambraia, publicado em 2017, vem à luz como a primeira edição a divulgar o texto crítico da tradução medieval portuguesa do Livro de Isaac, tratado ascético escrito originalmente em siríaco por volta de fins do século VII por Isaac de Nínive. Trabalho minucioso, realizado com base no confronto dos quatro testemunhos supérstites em que a tradução foi preservada. É uma edição crítica com o objetivo de restituir a forma genuína do texto, a forma original da tradução portuguesa do livro em questão. Como o próprio autor afirma, trata-se de um "trabalho de síntese de um conjunto de estudos sobre o tema feitos entre maio de 1996 e abril de 2017" (CAMBRAIA, 2017, p. XIII). O livro apresenta, de modo muito bem fundamentado, quatro partes. Da primeira, constam informações relevantes sobre a vida de Isaac de Nínive e suas obras, especificamente sobre o Livro de Isaac, seu conteúdo, circulação na Idade Média portuguesa, percurso histórico, descrição dos testemunhos que compõem a sua tradição, características linguísticas, o estema e sua fortuna editorial. Da segunda, o texto crítico, as normas de edição, os critérios para a escolha do texto-base e variantes, a transcrição, casos especiais e o aparato crítico. Da terceira, o glossário seletivo. Da quarta, o índice de citações e referências bíblicas e patrísticas.
Sleep in cluster headache revisited: Results from a controlled actigraphic study
Authors: Lund Nunu LT , Snoer Agneta Henriette , Jennum Poul Jørgen , Jensen Rigmor Højland , Barloese Mads Christian J 
Published: November 2018

Background and aim Cluster headache attacks exhibit a nocturnal predilection, but little is known of long-term sleep and circadian rhythm. The aim was to compare actigraphy measures, firstly in episodic cluster headache patients in bout and in remission and, secondly, to compare each disease phase with controls. Methods Episodic cluster headache patients (ICHD III-beta), from the Danish Headache Center and healthy, age- and sex-matched controls participated. Sleep and activity were measured using actigraphy continuously for 2 weeks, along with sleep diaries and, for patients, also attack registration. Results Patients in bout (n = 17, 2.3 attacks/day) spent more time in bed (8.4 vs. 7.7 hours, p = 0.021) and slept more (7.2 vs. 6.6 hours, p = 0.036) than controls (n = 15). In remission (n = 11), there were no differences compared with controls. Neither were there differences between patients in the two disease phases. In five patients, attacks/awakenings occurred at the same hour several nights in a row. Conclusion Actigraphy offers the possibility of a continuous and long study period in a natural (non-hospital) environment. The study indicates that sleep does not differ between the bout and remission phase of episodic cluster headache. The repeated attacks/awakenings substantiate that circadian or homeostatic mechanisms are involved in the pathophysiology. The protocol was made available at ClinicalTrials.gov (NCT02853487).
The search for a container in a precarious environment
Authors: O’Mahony Judy , Bereen Siobhán 
Published: November 2018

This article explores the impact of the parallel process of a precarious environment on a multicultural therapy group for women survivors of torture and persecution who had sought asylum in Ireland. The environments for both therapists and group members were experienced as producing ‘unthinkable anxiety’ (Winnicott, 1962: 57). For the therapists, their context was of threatened dismissal due to organizational restructuring, and for the group members it was the threat of deportation. The impact shaped decisions pertaining to the dynamic administration of how the group should be conducted and for how long. It led to a clinical crisis when the anxiety in the group became enmeshed, provoking primitive defences which affected the capacity to think, and blocked understanding on the part of the therapists. Flexibility in the level of leadership activity allowed for a containing process to take place and the group to become the therapist (Sclapobersky, 2016: 210). This flexible approach enabled the naming of an anxiety for the group as a whole which bound together the fragmented, intense emotions, and opened up the reflective space to the contents the members wished to have contained (Hinshelwood, 1994: 102). All names have been changed and the group gave consent for the authors to write about this experience.