bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cover Image, Volume 74, Issue 4
Authors: Lidor Ofir , Dror Orit , Hamershlak Dor , Shoshana Nofar , Belausov Eduard , Zahavi Tirtza , Mozes‐Daube Netta , Naor Vered , Zchori‐Fein Einat , Iasur‐Kruh Lilach , Bahar Ofir 
Published: February 2018

The cover image, by Ofir Lidor et al., is based on the Research Article Introduction of a putative biocontrol agent into a range of phytoplasma‐ and liberibacter‐susceptible crop plants, DOI: 10.1002/ps.4775.
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Embryonic Stem Cell-Derived Mesenchymal Stem Cells (MSCs) Have a Superior Neuroprotective Capacity Over Fetal MSCs in the Hypoxic-Ischemic Mouse Brain
Authors: Hawkins Kate E. , Corcelli Michelangelo , Dowding Kate , Ranzoni Anna M. , Vlahova Filipa , Hau Kwan-Leong , Hunjan Avina , Peebles Donald , Gressens Pierre , Hagberg Henrik , de Coppi Paolo , Hristova Mariya , Guillot Pascale V. 
Published: February 2018

Abstract
Human mesenchymal stem cells (MSCs) have huge potential for regenerative medicine. In particular, the use of pluripotent stem cell-derived mesenchymal stem cells (PSC-MSCs) overcomes the hurdle of replicative senescence associated with the in vitro expansion of primary cells and has increased therapeutic benefits in comparison to the use of various adult sources of MSCs in a wide range of animal disease models. On the other hand, fetal MSCs exhibit faster growth kinetics and possess longer telomeres and a wider differentiation potential than adult MSCs. Here, for the first time, we compare the therapeutic potential of PSC-MSCs (ES-MSCs from embryonic stem cells) to fetal MSCs (AF-MSCs from the amniotic fluid), demonstrating that ES-MSCs have a superior neuroprotective potential over AF-MSCs in the mouse brain following hypoxia-ischemia. Further, we demonstrate that nuclear factor (NF)-κB-stimulated interleukin (IL)-13 production contributes to an increased in vitro anti-inflammatory potential of ES-MSC-conditioned medium (CM) over AF-MSC-CM, thus suggesting a potential mechanism for this observation. Moreover, we show that induced pluripotent stem cell-derived MSCs (iMSCs) exhibit many similarities to ES-MSCs, including enhanced NF-κB signaling and IL-13 production in comparison to AF-MSCs. Future studies should assess whether iMSCs also exhibit similar neuroprotective potential to ES-MSCs, thus presenting a potential strategy to overcome the ethical issues associated with the use of embryonic stem cells and providing a potential source of cells for autologous use against neonatal hypoxic-ischemic encephalopathy in humans.
Multicollinearity: How common factors cause Type 1 errors in multivariate regression
Authors: Kalnins Arturs 
Published: February 2018

Research Summary: In multivariate regression analyses of correlated variables, we sometimes observe pairs of estimated beta coefficients large in absolute magnitude and opposite in sign. T‐statistics are also large, suggesting meaningful findings. I found 64 recently published Strategic Management Journal articles with results exhibiting these characteristics. In this article, I demonstrate that such results may be Type 1 errors (false positives): If regressors are correlated via an unobservable common factor, estimated beta coefficients will misleadingly tend toward infinite magnitudes in opposite directions, even if the variables’ real effects are small and of the same sign. Diagnostics such as Variance Inflation Factors (VIF) will misleadingly validate Type 1 errors as legitimate results. After establishing general results via mathematical analysis and simulation, I provide guidelines for detection and mitigation.Managerial Summary: This article demonstrates mathematically how regression analyses with correlated independent variables may generate beta coefficients of opposite sign to the variables’ true effects. To assess the likelihood of this possibility, I propose that: if (a) absolute correlation of two independent variables is about ±0.3 or more (smaller correlations may be problematic for large data sets), (b) the two variables have beta coefficients of opposite sign, if correlated positively, and of the same sign, if correlated negatively, and (c) the bivariate correlation of one independent variable with the dependent variable is of the opposite sign from the beta coefficient, then the beta might be a false positive. To facilitate such analysis, authors should provide complete correlation tables, including dependent variables, interaction terms, and quadratic terms.
Novel 2D Layered Molybdenum Ditelluride Encapsulated in Few‐Layer Graphene as High‐Performance Anode for Lithium‐Ion Batteries
Authors: Ma Ning , Jiang Xiao‐Yu , Zhang Lu , Wang Xiao‐Shuang , Cao Yu‐Liang , Zhang Xian‐Zheng 
Published: February 2018

AbstractMolybdenum ditelluride nanosheets encapsulated in few‐layer graphene (MoTe2/FLG) are synthesized by a simple heating method using Te and Mo powder and subsequent ball milling with graphite. The as‐prepared MoTe2/FLG nanocomposites as anode materials for lithium‐ion batteries exhibit excellent electrochemical performance with a highly reversible capacity of 596.5 mAh g−1 at 100 mA g−1, a high rate capability (334.5 mAh g−1 at 2 A g−1), and superior cycling stability (capacity retention of 99.5% over 400 cycles at 0.5 A g−1). Ex situ X‐ray diffraction and transmission electron microscopy are used to explore the lithium storage mechanism of MoTe2. Moreover, the electrochemical performance of a MoTe2/FLG//0.35Li2MnO3·0.65LiMn0.5Ni0.5O2 full cell is investigated, which displays a reversible capacity of 499 mAh g−1 (based on the MoTe2/FLG mass) at 100 mA g−1 and a capacity retention of 78% over 50 cycles, suggesting the promising application of MoTe2/FLG for lithium‐ion storage. First‐principles calculations exhibit that the lowest diffusion barrier (0.18 eV) for lithium ions along pathway III in the MoTe2 layered structure is beneficial for improving the Li intercalation/deintercalation property.
Technical and social problems of nuclear waste
Authors: Ramana M. V. 
Published: February 2018

Despite decades of effort, the nuclear industry does not yet have a working solution for managing spent fuel and high level waste, the most radioactive products generated by nuclear power plants. Although many scientific and technical bodies have endorsed geological disposal as the preferred solution to this problem, there remain significant uncertainties about the long‐term performance of repositories and behavior of the nuclear wastes to be stored in these facilities. Apart from a minority of countries, most countries have not chosen any sites for a repository. Further concerns about the long‐term safety of repositories arise from the experiences of failures and accidents at pilot facilities. One reason for the absence of operating repositories decades after they were first proposed is widespread public opposition to such facilities. Polls have revealed that substantial majorities of people consider nuclear waste with dread and do not approve plans to dispose of radioactive wastes near them, or, often, far away either. Nuclear power advocates have typically dismissed public concerns as resulting from a lack of understanding of scientific facts but this explanation does not withstand scrutiny. Technical approaches to dealing with nuclear waste, such as reprocessing of spent fuel, mischaracterize the social concerns and therefore do not help gain public acceptance. Concern about radioactive waste has contributed to the failure of the propaganda effort by the nuclear industry to market nuclear power as a solution to climate change. The absence of a solution to waste negatively affects the future expansion of nuclear energy.This article is categorized under:
Nuclear Power > Climate and Environment
Nuclear Power > Economics and Policy
Nuclear Power > Science and Materials
Reconciling the biogeography of an invader through recent and historic genetic patterns: the case of topmouth gudgeon Pseudorasbora parva
Authors: Hardouin Emilie A. , Andreou Demetra , Zhao Yahui , Chevret Pascale , Fletcher David H. , Britton J. Robert , Gozlan Rodolphe E. 
Published: February 2018

AbstractThe genetic variability and population structure of introduced species in their native range are potentially important determinants of their invasion success, yet data on native populations are often poorly represented in relevant studies. Consequently, to determine the contribution of genetic structuring in the native range of topmouth gudgeon Pseudorasbora parva to their high invasion success in Europe, we used a dataset comprising of 19 native and 11 non-native populations. A total of 666 samples were analysed at 9 polymorphic microsatellite loci and sequenced for 597 bp of mitochondrial DNA. The analysis revealed three distinct lineages in the native range, of which two haplogroups were prevalent in China (100%), with a general split around the Qinling Mountains. Dating of both haplogroups closely matched past geological events. More recently, its distribution has been influenced by fish movements in aquaculture, resulting in gene flow between previously separated populations in Northern and Southern China. Their phylogeography in Europe indicate as few as two introductions events and two dispersal routes. Microsatellite data revealed native populations had higher genetic diversity than those in the invasive range, a contrast to previous studies on P. parva. This study confirms the importance of extensive sampling in both the native and non-native range of invasive species in evaluating the influence of genetic variability on invasion success.
The changing social organization of prison protection markets: when prisoners choose to organize horizontally rather than vertically
Authors: Gundur R. V. 
Published: February 2018

AbstractThis article revisits the framework which Buentello et al. (Prison J 71(2): 3–14, 1991) created to describe the development of inmate solidarity groups into prison gangs in the Texas Department of Corrections. Interviews with current and former prison gang members in Texas, Arizona, and Illinois augment the current published literature on prison gangs in California. This article argues that the responses which prison administrations make to prisoners’ social orders are not static and have, in some cases, caused vertically configured groups to evolve into horizontally configured groups. These structural changes in prison gangs affect the gangs’ ability to affect control in the criminal underworld outside prison. Accordingly, although the challenges which prison administrations present to vertically developed social orders within prison may improve the administrations’ control within the prison walls, they may effectively decrease criminal-led social control on the street, leading to an increase in street-level violence.
Erratum to: Metamaterial-based graphene thermal emitter
Authors: Shi Cheng , Mahlmeister Nathan H. , Luxmoore Isaac J. , Nash Geoffrey R. 
Published: February 2018

The article Metamaterial-based graphene thermal emitter, written by Cheng Shi, Nathan H. Mahlmeister, Isaac J. Luxmoore, and Geoffrey R. Nash, was originally published electronically on the publisher’s internet portal (currently SpringerLink) on December 6th 2017 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed in February 2018 to © The Author(s) 2018 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.The original article has been corrected.
Integrated Modeling of Carburizing-Quenching-Tempering of Steel Gears for an ICME Framework
Authors: Khan Danish , Gautham BP 
Published: February 2018

AbstractIn order to leverage the concept of integrated computational materials engineering (ICME) for manufacturing of high-performance automotive transmission components such as steel gears, it is important to bring a closer collaboration between geometrical design, material selection, and manufacturing design stages for these components. This can be achieved by making the manufacturers aware of the implications of the decisions taken during each of these stages on material and its underlying microstructure. In order to facilitate this, it is necessary to model the evolution of the microstructure in the process-chain and its resultant properties. With this view, the current work focusses on development of an integrated modeling scheme of carburizing, quenching, and tempering processes using chemical composition-dependent, microstructure-based models intended to be used in an ICME framework for steel gear manufacturing. The individual process models are implemented in the commercial FEM suite ABAQUS™, with essential microstructure physics incorporated via user-subroutines. The individual process-models and their sequential integration are validated against experimental case-studies from literature. After validation, the integrated modeling scheme is automated by writing appropriate pre-processing and post-processing wrapper scripts, leading to the development of an independent manufacturing module that can be used in an ICME workflow. Finally, the utility of this module is demonstrated by using it for the exploration of the manufacturing process design and material selection scenarios for the production of a typical spur gear.
Forecasting potential evapotranspiration by combining numerical weather predictions and visible and near-infrared satellite images: an application in southern Italy
Authors: Chirico G. B. , Pelosi A. , De Michele C. , Falanga Bolognesi S. , D'Urso G. 
Published: February 2018

AbstractIrrigation according to reliable estimates of crop water requirements (CWR) is one of the key strategies to ensure long-term sustainability of irrigated agriculture. In southern Mediterranean regions, during the irrigation season, CWR is almost totally controlled by the potential evapotranspiration of the irrigated crop. An innovative system for forecasting crop potential evapotranspiration (ETp) has been implemented recently in the Campania region (southern Italy). The system produces ETp forecasts with a lead time of up to 5 days, by coupling the visible and near-infrared crop imagery with numerical weather prediction outputs of a limited area model. The forecasts are delivered to farmers with a simple and intuitive web app interface, which makes daily real-time ETp maps accessible from desktop computers, tablets and smartphones. Forecast performances were evaluated for maize fields of two farms in two irrigation seasons (2014–2015). The mean absolute bias of the forecasted ETp was <0.3 mm/day and the RMSE was <0.6 mm/day, both for lead times up to 5 days.
Bisphosphonate-induced osteonecrosis of the ear canal: our experience and a review of the literature
Authors: McCadden L , Leonard C G , Primrose W J 
Published: February 2018

AbstractBackground:Oesophageal disorders and osteonecrosis of the jaw are recognised complications of the commonly prescribed medication bisphosphonate. Despite these diagnoses being seen comparatively frequently within the ENT clinic, osteonecrosis of the external ear is a less well reported complication.Methods:The current literature is reviewed and our experience with six cases of bisphosphonate-related ear canal osteonecrosis is presented.Results:Six cases were identified as suffering from ear canal osteonecrosis as a result of bisphosphonate treatment. One of our cases suffered bilateral ear canal osteonecrosis after only 20 months of oral alendronic acid treatment. Management ranged from bisphosphonate cessation and topical treatment, to surgical debridement in the operating theatre.Conclusion:Bisphosphonate-related ear canal osteonecrosis is undoubtedly under-diagnosed. For such a commonly prescribed medication, the risks and side effects of bisphosphonate should be better known and long-term treatment should be avoided if possible.
Analysing Chinese Civil–Military Relations: A Bottom-Up Approach
Authors: Ledberg Sofia K. 
Published: February 2018

AbstractThis article examines Chinese civil–military relations using a bottom-up analytical approach and hitherto untapped sources, including interviews with military personnel in active service. It argues that traditional approaches to political control, which generally interpret the changing political–military relationship through military professionalism and institutional autonomy, miss out on important aspects and may generate erroneous conclusions. Here, focus is instead on the professional autonomy of the Chinese officer corps. Through an empirical study of the organization of military work at two of China's top military education institutes, the article illustrates how professional autonomy and direct political control vary, both between hierarchical levels and issue areas. This highlights the multidimensionality of both control and professional manoeuvrability and underlines the fruitfulness of including an intra-organizational perspective in order to reach better informed conclusions about political control and civil–military relations in today's China.
Lower limb exercise generates pulsatile flow into the pulmonary vascular bed in the setting of the Fontan circulation
Authors: Cordina Rachael , Celermajer David S. , d’Udekem Yves 
Published: February 2018

AbstractThe absence of a subpulmonary ventricle in the Fontan circulation results in non-pulsatile pulmonary blood flow. Lower limb exercise in this setting can generate pulsatile pulmonary blood flow.
Collecting amino acids in the Enceladus plume
Authors: Guzman Melissa , Lorenz Ralph , Hurley Dana , Farrell William , Spencer John , Hansen Candice , Hurford Terry , Ibea Jassmine , Carlson Patrick , McKay Christopher P. 
Published: February 2018

AbstractWe numerically model the dynamics of the Enceladus plume ice grains and define our nominal plume model as having a particle size distributionn(R) ~R−qwithq= 4 and a total particulate mass rate of 16 kg s−1. This mass rate is based on average plume brightness observed by Cassini across a range of orbital positions. The model predicts sample volumes of ~1600 µg for a 1 m2collector on a spacecraft making flybys at 20–60 km altitudes above the Enceladus surface. We develop two scenarios to predict the concentration of amino acids in the plume based on these assumed sample volumes. We specifically consider Glycine, Serine, α-Alanine, α-Aminoisobutyric acid and Isovaline. The first ‘abiotic’ model assumes that Enceladus has the composition of a comet and finds abundances between 2 × 10−6to 0.003 µg for dissolved free amino acids and 2 × 10−5to 0.3 µg for particulate amino acids. The second ‘biotic’ model assumes that the water of Enceladus's ocean has the same amino acid composition as the deep ocean water on Earth. We compute the expected captured mass of amino acids such as Glycine, Serine, and α-Alanine in the ‘biotic’ model to be between 1 × 10−5to 2 × 10−5µg for dissolved free amino acids and dissolved combined amino acids and about 0.0002 µg for particulate amino acids. Both models consider enhancements due to bubble bursting. Expected captured mass of amino acids is calculated for a 1 m2collector on a spacecraft making flybys with a closest approach of 20 km during mean plume activity for the given nominal particle size distribution.
Diversity of lichen-associated filamentous fungi preserved in European Paleogene amber
Authors: Kettunen Elina , Schmidt Alexander R. , Diederich Paul , Grabenhorst Heinrich , Rikkinen Jouko 
Published: February 2018

ABSTRACTA diversity of filamentous microfungi was discovered from thallus surfaces of epiphytic lichens preserved in Bitterfeld and Baltic amber. We report seven distinct morphologies of dematiaceous hyphomycetes, some of which closely resemble species of the extant generaSporidesmium,Taeniolellas. lat. andTaeniolina. Both the placement of the fungi on their substrates and the exquisite preservation of delicate structures indicate that the fungi were fully developed before they were engulfed by fresh resin. The lichens probably grew on the trunks of resin producing trees and became embedded in resin flows together with their fungal associates. The findings demonstrate that a wide range of presumably specialised fungi have lived on living and decomposing lichen thalli at least since the Paleogene. The findings add an interesting new component to the as yet poorly known mycota of the ancient European amber forests.
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours
Authors: Ma Xiaotu , Liu Yu , Liu Yanling , Alexandrov Ludmil B. , Edmonson Michael N. , Gawad Charles , Zhou Xin , Li Yongjin , Rusch Michael C. , Easton John , Huether Robert , Gonzalez-Pena Veronica , Wilkinson Mark R. , Hermida Leandro C. , Davis Sean , Sioson Edgar , Pounds Stanley , Cao Xueyuan , Ries Rhonda E. , Wang Zhaoming , Chen Xiang , Dong Li , Diskin Sharon J. , Smith Malcolm A. , Guidry Auvil Jaime M. , Meltzer Paul S. , Lau Ching C. , Perlman Elizabeth J. , Maris John M. , Meshinchi Soheil , Hunger Stephen P. , Gerhard Daniela S. , Zhang Jinghui 
Published: February 2018

Abstract
Analysis of molecular aberrations across multiple cancer types, known as pan-cancer analysis, identifies commonalities and differences in key biological processes that are dysregulated in cancer cells from diverse lineages. Pan-cancer analyses have been performed for adult1,2,3,4 but not paediatric cancers, which commonly occur in developing mesodermic rather than adult epithelial tissues5. Here we present a pan-cancer study of somatic alterations, including single nucleotide variants, small insertions or deletions, structural variations, copy number alterations, gene fusions and internal tandem duplications in 1,699 paediatric leukaemias and solid tumours across six histotypes, with whole-genome, whole-exome and transcriptome sequencing data processed under a uniform analytical framework. We report 142 driver genes in paediatric cancers, of which only 45% match those found in adult pan-cancer studies; copy number alterations and structural variants constituted the majority (62%) of events. Eleven genome-wide mutational signatures were identified, including one attributed to ultraviolet-light exposure in eight aneuploid leukaemias. Transcription of the mutant allele was detectable for 34% of protein-coding mutations, and 20% exhibited allele-specific expression. These data provide a comprehensive genomic architecture for paediatric cancers and emphasize the need for paediatric cancer-specific development of precision therapies.