bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reaction of the hemostatic system in response to hypercapnic hypoxia of maximum intensity ­depending on different types of preconditioning
Authors: Moskalenko S V , Shakhmatov I I , Kovalev I V , Shakhmatova K I , Vdovin V M 
Published: August 2019

Aim. To study the adaptation reactions of the hemostasis system to hypercapnic hypoxia of maximum intensity in rats subjected to preliminary multiple exposure to ethylmethylhydroxypyridine succinate and hypercapnic hypoxia of submaximal intensity.
Methods. In the experiment, Wistar male rats (80 individuals) were used. Training cycles: 30-fold daily exposure to hypercapnic hypoxia of submaximal intensity (20 minutes — 9.0±0.5% O2, 7.0±0.5% CO2); administration of ethylmethylhydroxypyridine succinate (50 mg/kg) to animals for 30 days; combined effects of the two described modes. Tested experimental exposure was simulated as a single hypercapnic hypoxia of maximum intensity (20 minutes — 5.0±0.5% O2, 5.0±0.5% CO2) at the end of each of three 30-day training cycles.
Results. Preliminary 30-day exposure to both isolated hypercapnic hypoxia of submaximal intensity and combined exposure to ethylmethylhydroxypyridine succinate contributes to hypocoagulation shift in the hemostasis system and reduces the level of the markers of pre-thrombotic state in response to a single hypercapnic hypoxia of maximum intensity. The state of the hemostasis system after 30-day cycle of isolated use of an antihypoxant is characterized by the inhibition of the vascular-platelet system of the hemostasis system and preserved hypercoagulation shifts in its plasma unit. The obtained results suggest that both preliminary isolated effect of hypercapnic hypoxia of submaximal intensity and the combined effect of hypercapnic hypoxia and ethylmethylhydroxypyridine succinate increase the resistance of the hemostasis system in experimental animals to acute hypercapnic hypoxia of maximum intensity compared to rats of the control group. This was confirmed by the inhibition of the vascular-platelet system, hypocoagulation in the plasma unit, decrease in the level of thrombotic readiness markers and increase in the anticoagulant activity of the blood system compared to the control. At the same time, isolated course administration of ethylmethylhydroxypyridine succinate did not cause the same amount of adaptive changes to maximum intensity hypercapnic hypoxia, since only platelet suppression of the hemostasis and hypocoagulation via the internal coagulation pathway were registered.
Conclusion. Isolated exposure of hypercapnic hypoxia of submaximal intensity and its combined exposure with ethylmethylhydroxypyridine succinate increase the resistance of the hemostasis system to acute hypercapnic hypoxia of maximum intensity; isolated course administration of ethylmethylhydroxypyridine succinate does not cause the same amount of adaptive changes.
Clinical course and remission rate in adult patients with atopic asthma in Chelyabinsk
Authors: Ignatova G. L. , Zhorina Yu. V. , Abramovskikh O. S. , Zherebtsova I. A. 
Published: August 2019

Data on asthma remission in adults are scarce worldwide and have not been searched in Russian Federation.The aimof the study was to describe clinical course and remission rate in adult patients with atopic asthma in Chelyabinsk.Methods. A retrospective analysis of 313 outpatient records of patients with atopic asthma aged 18 to 70 years was carried out. The patients were followed from 1992 to 2018. The median duration of the follow-up was 8 (5; 15) years. Then, the patients were surveyed by phone. Asthma Control Test (AСT) was used in 181 (58%) of 313 respondents. Clinical remission of asthma was determined as being symptom-free with no need in inhaled corticosteroids (ICSs) and short-acting β2-agonists (SABAs) during ≥ 1 year.Results. The median age of asthma onset was 14.5 (8; 2) years in males and 28 (24; 36) years in females (p < 0.001). The diagnosis was made 5 years after the onset of symptoms. Asthma severity was related to gender: mild asthma was seen more often in males compared to females (p = 0.008). Allergic rhinitis and asthma comorbidity was found in 78% of patients. The proportion of patients sensitized to pollen was 72%; tree pollen allergens were the main cause of seasonal allergy (in 51% of patients). Different combinations of sensitization to indoor, animal, and pollen allergens (polysensitization) were detected in 80% of patients. Clinical remission of atopic bronchial asthma was determined in 22.7% of cases. Asthma remission was not related to the patient’s gender or age of symptom onset. The median age of the remission group patients was 33 (28; 39.5) years vs 40 (29; 51) years in patients without remission (p = 0.015). Asthma remission was associated with normal body mass index (23 (21; 24) kg / m2 vs 25 (22; 29) kg / m2 (p = 0.007); allergen elimination (p < 0.001) and allergen-specific immunotherapy (p < 0.001).Conclusion. Predicting the probability of asthma remission and identifying conditions required to achieve the remission could improve our knowledge about asthma natural course and could increase treatment efficacy and adherence of patients to the treatment.
Mitigating a Nursing School's Impact on Climate Change: A Quality Improvement Project
Authors: Yang Bee , Demorest Shanda , Krzyzanowski Breanne 
Published: August 2019

Background Mitigation is one approach to addressing climate change, which focuses on reducing carbon dioxide and greenhouse gas emissions. Nurses play a critical role in mitigation to prevent the health impacts of climate change. Recommendations to mitigate climate change in higher education institutions reflect four themes: policy, people, process, and practice. This quality improvement project aimed to mitigate a metropolitan nursing school's impacts on climate change. Methods A Sustainability Champion Workgroup was formed to address gaps identified in the organizational needs assessment. A No Waste November (NWN) campaign and a Sustainability dashboard were created to engage participants and increase awareness about climate change and environmentally sustainable behaviors. A pre- and post-NWN survey, adapted from the Nurses ‘Environmental Awareness Tool, and waste disposal measurements over 6 weeks were used to assess the impact of these interventions. Results The post-NWN survey showed the greatest increases in mean scores for the following environmentally sustainable behaviors: biking, walking, carpooling, or taking public transportation to work; leading or participating in recycling initiatives; serving on committees that purchase sustainable supplies; and composting. Waste disposal measurements revealed a higher proportion of recycling to landfill waste during 5 out of the 6 weeks of measurement. Conclusion Nurses and higher education institutions play an important role in mitigating the human impacts on climate change through environmental sustainability initiatives. Barriers to adopting environmentally sustainable behaviors and incentives to support these behaviors also need to be examined and addressed in future projects.
DEVELOPMENT OF PERFORMANCE EVALUATION THEME: A SYSTEMATIC ANALYSIS OF THE LITERATURE
Authors: Matos Lucas dos Santos , Valmorbida Sandra Mara Iesbik , Martins Vinicius Abilio , Ensslin Sandra Rolim 
Published: August 2019

This research aimed to identify the development of literature on performance evaluation. It is an exploratory and descriptive research study, with a quali-quantitative approach through bibliometric analysis, using the ProKnow-C intervention instrument. The analyses showed that the main featured article was by Neely, Gregory and Platts (1995). The most influential article in the portfolio was Bourne et al. (2000), with the highest level of betweenness. The Balanced Scorecard is the tool that predominates in 23% of studies; in 30% of the works, was developed by proposing models based on the literature while in 24% of them it was based on a proposal developed by the authors. The study contributed to broaden the knowledge about the subject in order to allow an overview of the literature, when knowing the main authors working on the theme, periodicals, articles, themes, tools and areas of practice. Emerging views on the subject are also presented.
Hubungan Pendapatan dan Status Ketahanan Pangan Rumah Tangga di Wilayah Pesisir di Kecamatan Sidoarjo Kabupaten Sidoarjo (Studi Penelitian di Dusun Kalikajang Kelurahan Gebang)
Authors: Susanti Aisyah Fitria 
Published: August 2019

Background: Household food security in coastal areas can be seen from indicators of availability, access, food utilization and stability. One of the pillars of house hold food security can be influenced by household income.Objective: This study aimed to analyze the relationship between the level of household income and the status of household food security in isolated coastal areas in Kalikajang Hamlet, Gebang Sub-District, District of Sidoarjo, Sidoarjo Regency.Method: This type of research was observational study with cross sectional design. The population in this study were all households in the area of Kalikajang Hamlet, Sub-District of Gebang. Sample was determined using simple random sampling technique and using formula from Lemeshow, resulted in 52 respondents included in this study. Primary data was collected through interviews with questionnaires. Data analysis using Chi Square statistical test to test the relationship between independent variables and dependent variables, and logistic regression tests to test whether there is a relationship between all independent variables with the dependent variable.Results: The results of the study showed that from the eight of independent variables tested, there was one variable that was positively related to the level of household food security, namely household income (p-value<0.001).Conclusion: There is a significant relationship between the level of income and the status of household food security in coastal areas in the District of Sidoarjo.ABSTRAKLatar Belakang: Ketahanan pangan rumah tangga di wilayah pesisir dapat dilihat dari indikator ketersediaan, akses, pemanfaatan pangan dan stabilitas. Salah satu pilar yang mempengaruhi adalah pendapatan rumah tangga.Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan antara tingkat pendapatan rumah tangga dengan status ketahanan pangan rumah tangga di wilayah pesisir tambak terisolir di Dusun Kalikajang, Kelurahan Gebang, Kecamatan Sidoarjo, Kabupaten Sidoarjo.Metode: Jenis penelitian adalah observasional dengan desain cross sectional. Populasi pada penelitian ini yaitu seluruh rumah tangga yang berada di wilayah Dusun Kalikajang Kelurahan Gebang. Teknik penentuan sample menggunakan simple random sampling dengan rumus dari Lemeshow dan didapatkan 52 responden. Data Primer dikumpulkan dengan wawancara dengan kuesioner. Analisis data menggunakan uji statistik Chi Square untuk menguji hubungan antar variabel bebas dan variabel dependen, dan uji regresi logistik untuk menguji adakah hubungan seluruh variabel bebas dengan variabel terikat.Hasil: Hasil penelitian menunjukkan dari delapan variabel independen yang diujikan, terdapat satu variabel yang berhubungan positif dengan tingkat ketahanan pangan rumah tangga, yaitu pendapatan rumah tangga (p-value<0.001).Kesimpulan: Terdapat hubungan yang bermakna antara tingkat pendapatan dengan status ketahanan pangan rumah tangga di wilayah pesisir di Kecamatan Sidoarjo.
The effect of educational intervention based on health belief on improvement of metabolic indices of patients with diabetes type II living in rural areas
Authors: Falahati Ebrahim , Abdi Alireza , Ashterian Hossein , Salari Nader , Momenfar Farzad 
Published: August 2019

Abstract
Background: Nowadays, diabetes is one of the most common health problems worldwide that may cause severe side effects on the circulatory system, nervous system, kidneys, eyes, and feet. Health care education makes patients involved in caring and it is one of the main measures to attenuate the load of the disease on health system. The present study is an attempt to survey the effect of health belief-based educational intervention on improvement of metabolic indices in patients with diabetes type II in rural areas of Kermanshah-Iran.
Methods: The study was carried out as a clinical trial in 2018 on 48 individuals grouped into intervention and control groups (each with 24 members) randomely. The participants were patients with diabetes type II visiting rural comprehensive services centers of Pave-Kermanshah-Iran. They were selected randomly so that visitors to Shamshir Village clinic of were selected as the intervention group and the patients in Serias and Darebaian villages’ centers were selected as the control group. Data gathering was done using demographics questionnaire and a metabolic indices checklist before and three months after the educational intervention. The participants in the intervention group were grouped into two groups of 12-15 members and the intervention was conducted based on health belief model in six sessions each for 60 minutes. Data analyses were done using SPSS (v.24) and descriptive statistics and Squared Chi test, Wilcoxon test, Mann Whitney test, independent t-test, and paired t-test.
Findings: Before the intervention, there was no significant difference between the two groups in terms of demographics and diabetes metabolic indices (P>0.05). However, after the intervention, there was a significant difference between the two groups in terms of glycated hemoglobin (p=0.038) and fasting blood glucose level (P=0.006). The difference between the two groups was not significant in terms of BMI (p=0.301), cholesterol level (p=0.797), triglyceride (p=0.439), lipoprotein with low density (p=0.157), and lipoprotein with high density (p=0.664).
Conclusion: The results showed that health belief-based educational intervention was effective in decreasing blood glucose level in diabetic patients. It is recommended using this approach as a part of therapeutic intervention and disease control in diabetic patients.
Relationship between acculturation and blood pressure in Somali immigrants living in Minneapolis-St. Paul, Minnesota
Authors: Dalmar Ahmed , Martinson Brian C. , Brown Morgan , Singh Maharaj , Pryce Douglas , Maciosek Michael V. , Farah Farhiya , Ott Miles , Westgard Bjorn 
Published: August 2019

Abstract
Background Immigrant acculturation to the United States has been found to correlate with cardiovascular risks. Little extant research has evaluated the relationship between acculturation and blood pressure in Somali immigrants. Methods We surveyed and measured blood pressures of 1156 Somali immigrants in Minneapolis-St. Paul, Minnesota. Latent class analysis identified four distinct acculturation subgroups. We examined the data for predictors of hypertension using generalized estimating equations. Results Our sample was majority female (62.4%), mean age 47.9 ± 18.4 years, mean baseline body mass index 30.2 ± 8.6 kg/m2 and mean years in U.S. of 9.9 ± 6.1. Multivariate regression showed that one acculturation group (low English, high trust) was less likely to be hypertensive. Conclusion We found no relationship between several measures of acculturation and hypertension. We found a difference between one of our acculturation groups and the others, suggesting a more complex relationship between acculturation and hypertension among Somali immigrants.
Why online medical teams disband? The role of team diversity and leadership type
Authors: Li Jiaying , Wu Hong , Deng Zhaohua , Evans Richard , Hong Ziying , Liu Shan 
Published: August 2019

Abstract
Background
Medical teams (MTs) online can provide comprehensive and rapid healthcare services to patients through doctors’ collaboration. The growth of MTs continues with their increasing popularity among doctors and patients, but there also exists some disbanded MTs, which would break the continuity of healthcare services. We aim to addressing this pressing issue by exploring effects of team diversity and leadership types on the team status (i.e. team disbandment). Specifically, we classify team diversity into separation diversity, variety diversity and disparity diversity, and leadership types based on the clinical titles include strong, equal and weak types.
Methods
A dataset of 1,071 MTs online were traced from the Good Doctor Online, a leading online health community (OHC) in China on January 10, 2018, and 206 teams disbanded after 3 months. Logistic regression and Maximize Likelihood Estimation were used to examine their effects.
Results
Our findings suggest that variety diversity related to the departments positively affected team disbandment, but disparity diversity referring to the clinical titles negatively affected team disbandment. Separation diversity in terms of the members’ attitude exerted a negligible influence on team disbandment. Although strong and equal leadership negatively influenced team disbandment, they strengthened the positive effect of variety diversity, suggesting the stable structure matching of strong/equal-type leadership and low department diversity, and the matching of weak-type leadership and high department diversity.
Conclusion
This study focuses on effects of leadership types and team diversity, and their pairwise combinations are obtained to effectively reduce the disbandment probability of medical teams in OHCs. It could help platforms, team founders, and all those connected with MTs positively deal with the team disbandment crisis. Theoretical and practical implications in OHCs and limitations were discussed.
Towards the Elimination of Dog-Mediated Rabies: Development and Application of an Evidence-Based Management Tool
Authors: Rysava Kristyna , Hampson Katie , Haydon Daniel , Johnson Paul , Mancy Rebecca , Vilas Victor Del Rio , Mancero Tamara , de Carvalho Mary Freire , Vigilato Marco , Caldas Eduardo , Castro Andre , Montebello Lucia , Rocha Silene , Gutierrez Veronica , Roldan Jesus Gonzalez 
Published: August 2019

Abstract
Background: International organizations advocate for the elimination of dog-mediated rabies, but there is only limited guidance on interpreting surveillance data for managing elimination programmes. With the regional programme in Latin America approaching elimination of dog-mediated rabies, we aimed to develop a tool to evaluate the programme’s performance and generate locally-tailored rabies control programme management guidance to overcome remaining obstacles. Methods: We developed and validated a robust algorithm to classify progress towards rabies elimination within sub-national administrative units, which we applied to surveillance data from Brazil and Mexico. The method combines criteria that are easy to understand, including logistic regression analysis of case detection time series, assessment of rabies virus variants, and of incursion risk. Subjecting the algorithm to robustness testing, we further employed simulated data sub-sampled at differing levels of case detection to assess the algorithm's performance and sensitivity to surveillance quality. Results: Our tool demonstrated clear epidemiological transitions in Mexico and Brazil: most states progressed rapidly towards elimination but few regressed due to incursions and control lapses. In 2015, dog-mediated rabies continued to circulate in the poorest states, with foci remaining in only 1 of 32 states in Mexico, and 2 of 27 in Brazil, posing incursion risks to the wider region. The classification tool was robust in determining epidemiological status irrespective of most levels of surveillance quality. In endemic settings, surveillance would need to detect less than 2.5% of all circulating cases to result in misclassification, whereas in settings where incursions become the main source of cases the threshold detection level for correct classification should not be less than 5%. Conclusion: Our tool provides guidance on how to progress effectively towards elimination targets and tailor strategies to local epidemiological situations, while revealing insights into rabies dynamics. Post-campaign assessments of dog vaccination coverage in endemic states, and enhanced surveillance to verify and maintain freedom in states threatened by incursions were identified as priorities to catalyze progress towards elimination. Our finding suggests genomic surveillance should become increasingly valuable during the endgame for discriminating circulating variants and pinpointing sources of incursions.
The different compensatory mechanism of sagittal spinopelvis in patients with LDH and patients with spondylolisthesis
Authors: Wu Weifei , Liang Jie , Chen Ying , Yang Zong , Ru Neng , Zhang Fan , Nie Ke 
Published: August 2019

Abstract
Background: few studies focusing on the differences of spinopelvic alignment between patients with LDH and patients with SPL were reported. The aim of this study was to study differences of spinopelvic alignment and to analyze differences of correlation between sagittal alignment parameters among patients with LDH and SPL, and normal population.
Methods: Standard up-standing antero-posterior and lateral X-ray of the whole spine were preformed in all subjects. Evidence of LDH was confirmed by CT or MRI. SPL was diagnosed by X-ray or MRI. The parameters were measured included TK, LL, PI, SS, PT and SVA in lateral radiography.
Results: 60 patients with LDH, 62 patients with SPL and 57 normal were included. Significant differences as for the SS, TK, LL and SVA (P <0.05) was found among three groups. PI of SPL patients was the highest among the three groups (P <0.05). PT of both SPL patients and LDH patients were significant higher than controls’ (P <0.05). LL of LDH patients was the lowest among the three groups (P <0.05). PI was less correlated with LL (P <0.05) in patients with LDH and SPL. PT was more strongly negative correlated with SS, LL and TK in LDH group (P <0.05). SS was more strongly positive correlated with TK (P <0.05), and SS and LL were more strongly negative correlated with SVA (P <0.05) in LDH patients.
Conclusion: Those results showed a disharmonious spinopelvic relationship and exhibited different compensatory models of spine to adapt changes in spinal alignment in LDH patients and SPL patients.