bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Listening Effort Experience in Normal and Hearing Impaired Adult Population
Authors: Salah Sarah Mohamed , El-Kabarity Rasha , El-Kholi Wafaa , Kamal Nadia 
Published: November 2024

Abstract

Background
Hearing impaired patients often report difficulties on attending to auditory message. These difficulties are not only exclusive to understanding the auditory message, rather, the process itself become effortful and induce tiredness or fatigue. While conventional Puretone audiometry and speech audiometry are efficient tools to access hearing impaired individuals, they do not address the perceived Listening Effort (LE) that the patient faces on daily basis. Accordingly, LE assessment tools represent a relatively new dimension in evaluating hearing impaired population. These tools include a subjective self-report questionnaires as the Speech, Spatial, Qualities of hearing scale (SSQ), a behavioral tool such as the dual task paradigms, and an objective physiological tool such as pupillometry, skin conductance, heart rate, Electroencephalography (EEG), functional magnetic resonance imaging(fMRI). This study has used subjective self-rating Arabic version of SSQ scale, and an objective physiological tool which is pupillometry to measure LE for adult hearing aid users.

Aim of the Work
To standardize LE assessment tools namely the Arabic version of SSQ, and Pupillometry in normal hearing adults. To assess LE in adult Hearing aids (HA) users to investigate whether they still suffer even after being optimally fitted with HA.

Patients and Methods
The study consisted of one hundred and eleven adult individuals divided into two groups; a normal hearing group (sixty normal individuals) with mean age 40 years and a study group (fifty-one HA users with bilateral symmetrical sensorineural hearing loss of variable degrees) with mean age 35 years and hearing loss duration ranging from 2-49 years. Patients were recruited from Audiology Unit, ORL department, Ain Shams University. Listening effort was measured by a subjective self-report scale (Arabic version of Speech, Spatial, and Qualities of Hearing scale (SSQ)), and a physiological objective tool (Pupillometry) to measure pupil dilation quotient.

Results
Hearing aid users group revealed statistically significant increased listening effort for both subjective and objective methods referenced to age matched normal group.

Conclusions
Listening effort test battery is clinically feasible in audiology practice and could help understand the challenges the hearing impaired faces. HA algorithms and technology have not resolved LE for the majority of HA users.
Risk of Developing Chronic Kidney Disease among Obese Metabolically Free Adults: A Systematic Review/Meta-Analysis
Authors: Mousa Abeer Mohammed Mahmoud , Abdel-Wahab Saeed , Essam El-Din Ghada , Abdel mobdy Ashraf , Mostafa Salwa , Abd El Samea Marwa Shaban 
Published: November 2024

Abstract

Background
Metabolically healthy obesity (MHO) is a type of obesity characterized by a favorable metabolic picture. Yet, the relationship between chronic kidney disease (CKD) and MHO has not been established. This review investigates the relationship between the metabolic healthy phenotype of obesity and the development or progression of CKD.

Objective
To determine the risk of development or progression of chronic kidney disease (eGFR &lt;60 ml/min/1.73 m2) in metabolically healthy obese individuals.

Methods
A literature search was performed in 5 databases using the following search strategies: (” chronic kidney disease” OR “end-stage renal disease” OR “estimated glomerular filtration rate” OR “kidney function”) AND (“obesity” OR “metabolic syndrome” OR “metabolically healthy” OR “metabolically healthy obesity” OR “overweight” OR “metabolically healthy overweight “OR “metabolic parameters” OR “metabolic profile” OR “obesity without metabolic abnormality” OR “healthy obesity”). We included prospective, retrospective cohort studies and case-control studies in English, French, Spanish, and Arabic until December 2022 that investigated the development or progression of CKD in adults &gt; 18 years with a baseline GFR of ≥ 60 ml/min/1.73 m2 exposed to MHO. A total of 12579 studies were retrieved, and 12564 were excluded due to different populations, exposures, or outcomes. Studies with missing data, narrative reviews, systematic reviews, meta-analyses, case reports, case series, and commentaries, along with studies conducted on animals, were also excluded. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for reporting.

Results
We included 15 cohort studies with 5,039,394 participants. MHO subjects showed an increased risk for CKD with a pooled risk ratio (RR) of 1.42, 95% CI (1.25–1.61), p &lt; 0.001 using the random effects model. Heterogeneity is high, as indicated by Cochrane Q = 73.35 and I squared (I2) = 81%.

Conclusion
Metabolic healthy obese adults have a significantly higher risk of the development or progression of CKD.
Glycogen Phosphorylase-BB and Corrected QT Interval in Early Prediction of Cardiotoxicity in Patients with Acute Aluminum Phosphide Poisoning
Authors: Abdulkhalik Asmaa Gamil , Azab Gehan Boshra , Nabil Hafez Rabab 
Published: November 2024

Abstract

Background
Aluminum phosphide (ALP) is a highly toxic pesticide that cause multi-organ affection. Cardiovascular affection accounts for high mortality. So, early prediction of myocardial injury and arrhythmias are important in the management.

Aim
This study aimed at investigating the role of Glycogen phosphorylase BB (GPBB) and corrected QT interval (QTc) in early prediction of ALP induced cardiotoxicity.

Methods and Results
The current study was a prospective study carried at Poison Control Center of Ain Shams University on thirty ALP intoxicated adults and thirty age and sex matched healthy controls. Patients were subjected to history taking, clinical examination, grading of severity according to Poison Severity Score (PSS) and on admission investigations including electrocardiogram (ECG) and GPBB. Outcome was also recorded. The results revealed that GPBB was higher in intoxicated patients than controls and there was significant difference among outcome groups. GPBB also was able to detect cardiotoxicity and predict mortality. QTc interval was longer in intoxicated patients than healthy controls and was able to predict occurrence of arrhythmias.

Conclusion
It was concluded that GPBB is a promising biomarker to predict myocardial injury following aluminum phosphide intoxication and on admission corrected QT interval is simple bed side tool to predict arrhythmias.

Recommendations
The present study recommended the use of GPBB and corrected QT interval as useful markers for prediction of ALP cardiotoxicity.
Single Versus Separate Incisions in Oncoplastic Breast Surgery Techniques
Authors: Elfiky Amr Kamel , Othman Farag Ahmed Gamal Eldin , Abd Almoaty Karim Fahmy , Ahmed Ahmed Abdelkader 
Published: November 2024

Abstract

Background
Patient concerns with aesthetics have prompted the improvement of oncoplastic surgical approaches. It has been shown that the aesthetic success in breast malignancy surgical treatment leads enhanced sexual and social recovery. In this study a prospective comparison between cohorts of early-stage breast cancer patients treated with oncoplastic breast surgery. The first cohort will be treated with the single incision approach and the second cohort will be treated by the conventional breast conservative technique, which will be performed with double incision (one for the tumour resection and the other for the axillary dissection).

Objective
to compare between single incision & separate incisions in approach to axillary lymph nodes in oncoplastic breast surgery.

Patients and Methods
This is a prospective cohort comparative study between single incision & separate incisions in approach to axillary lymph nodes in oncoplastic breast surgery. This study will be conducted at breast surgery unit at Ain Shams University Hospitals and Maddi Military Complex starting from June 2022 to June 2023. Approval of the Ethical Committee and written informed consent from all participants will be obtained.

Results
There was significant no statistical difference in both group as regards the operative timing, seroma and the hospital stay but there is a statistical difference regarding hematoma between the two groups. In our study, 86.7% of the patients attained good to excellent cosmetic outcomes (70% as excellent and 26.7% as good) regarding single incision and 79.7% of the patients attained good to excellent cosmetic outcomes (65% as excellent and 26.7% as good) regarding separate incision. High cosmetic outcome was obtained as the patients were satisfied with presence and shape of their breasts relatively.

Conclusion
The choice of the oncoplastic technique is mainly based upon the location of the tumor, size of the breast and distance of the tumor from the nipple areola complex. So all cases should be adequately reviewed in order to tailor the decisions for every single case. There is statistically difference between Single incision in breast cancer lesion and separate incision as regards hematoma and the cosmetic outcome.
Complications of Laparoscopic Management of GERD. Systematic Review and Meta Analysis
Authors: Hussien Khaled , Shaban Mohammed , Fawzy Fawzy Salah , El-Malah Ahmed Samir Shahhat Mohamed 
Published: November 2024

Abstract

Background
Anti-reflux surgery is an effective alternative to medical treatment of GERD and is the only definitive therapy for the prevention of its severe long-term consequences. For this reason, since its idealization by Nissen, who first described total fundoplication in 1956, it has gained a wide consensus in the international surgical community.

Aim of the Study
The aim of this study is to detect the types and incidence of postoperative complications after laparoscopic management of GERD.

Patients and Methods
These studies reported a total of 1791 patients, of whom 941 (52.69 %) underwent laparoscopic partial fundoplication (LPF) either Dor or Toupet and 850 (47.31 %) underwent laparoscopic Nissen fundoplication (LNF).

Results
There were no statistical differences between LPF and LNF in the perioperative events as operative time and interaoperative complications. This Meta-analysis revealed a significant difference in the late postoperative dysphagia parameter between the two arms of the study, in favour of LPF which has significantly less dysphagia than that recorded with LNF. However, it was found that lower esophageal sphnicter pressure (LESP)(objective parameter of dysphagia) is significantly higher in the group of LNF than that measured in the LPF group, As regard gas related sysmptoms in the form of gas bloating syndrome, ability to relieve bloating and ability to belch. When performing forest plot meta ananlysis for each complication of the gas related symptoms, It was found that there is no statistical difference between LPF and LNF. Also the same results of insignificant difference were obtained when estimating patient's satisfaction. Also, measuring of De meester score that evaluate acid reflux symptoms (objective), it was found that there is no significant difference between the LPF and LNF groups. But when estimating the use of antisecretory drugs (PPIs), this meta-analysis show significant less use of anti secretory drugs among the LNF groups than that the LPF group.

Conclusion
Both procedure partial and complete wrap are equally effective in controlling reflux symptoms and obtain a comparable prevalence of patient satisfaction. Dysphagia found to be significant after Nissen fundoplication when follow up is 5 years or more. Also there is significant use of antisecretory drugs among the group of partial fundoplication although there is no significant difference in the heart burn symptoms which means that depending on symptoms only is not always the right way of recurrence detection. Also more objective studies are needed to evaluate the clinical outcome and recurrence prior to offering re-visional surgery.
The Optimal Bilio Pancreatic Limb (BPL) Length in One Anastomosis Gastric Bypass (OAGB), A Systematic Review
Authors: Abdel Samea Kareem Sabry , Elsayed Mohamed Gamal , Mohamed Ahmed Taha 
Published: November 2024

Abstract

Background
The number of patients undergoing bariatric surgery for morbid obesity has progressively increased in the last 20 years worldwide. The procedures most performed nowadays are sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), accounting for 46% and 38.2% of all procedures, respectively. Among the other bariatric procedures, one anastomosis gastric bypass (OAGB) has rapidly gained acceptance and diffusion worldwide and represents 7.6% of all bariatric interventions The one anastomosis gastric bypass (OAGB) has currently gained a widespread diffusion among bariatric surgeons, being the third commonest procedure worldwide performed after sleeve gastrectomy and Roux-en-Y gastric bypass (RYGB). OAGB gained many supporters but also several criticisms for the possible onset of biliary reflux and malabsorption with consequent nutritional deficits

Objective
To find the most optimal length of biliopancreatic limb length in one anastomosis gastric bypass with best weight loss, outcomes and least possible malnutrition.

Patients and Methods
Out of the included studies, there was five Cohort study, while the remaining studies was RCT. Follow-up periods ranged between one and 12 months to 36 months. Regarding patients’ characteristics, 7343 patients were studied in the included articles.

Results
The rates of anemia were significantly higher in the long limb procedures due to the reduced capacity to absorb iron. However, we could not find significant differences between long and short limb procedures in the rates of iron deficiency; the small number of studies in such a comparison might have contributed to this finding.

Data Sources
Medline databases (PubMed, Medscape, ScienceDirect. EMF-Portal) and all materials available in the Internet till 2023.

Conclusion
While long limb surgery induced significantly higher weight loss than short limb procedures as indicated by %EWL and %TWL, long limb procedures were associated with multiple nutritional deficiencies, including hypoalbuminemia, hypoproteinemia, and hypocalcemia. Additionally, higher proportions of anemia and malnutrition were observed after long limb procedures compared to short limb procedures. The results should be interpreted with caution given the inherent limitations of studies’ design (primarily retrospective investigations) and the small number of studies that assessed nutritional differences over long follow-up periods. Future large- sized RCTs are required to assess the efficacy and safety of long limb procedures on weight loss and nutritional outcomes, considering the roles of BPL length, ethnic variation, gut hormonal response, and the malabsorptive paradigm of gastric bypass surgeries.
Evaluation of Biliopancreatic Limb Length in Laparoscopic One Anastomosis Gastric Bypass on Resolution of Metabolic Syndrome
Authors: Iskandaros Moheb Sharaby , Khalil Ahmed , Sabry Ahmed Mohamed , Ayad Amgad Adel 
Published: November 2024

Abstract

Background
One-anastomosis gastric bypass (OAGB) has been assessed in several studies, with most indicating excellent weight loss and improvement in comorbidities after OAGB.

Aims and Objectives
to compare the effect of biliopancreatic limb length (150cm versus 200cm) regarding weight loss, resolution of comorbidities and post-operative complications especially nutritional deficiency along 2 years of follow up.

Subjects and Methods
This Retrospective study was conducted at Ain Shams university hospital (Eldemerdash). It was carried out on 80 obese patients with type 2 diabetes mellitus who underwent laparoscopic mini gastric bypass.

Result
regarding Vit D3 (nmol/L) Deficiency, Ferritin (ng/mL) Deficiency, Albumin (g/dL) Deficiency, Ca (mg/dL) Deficiency, Vit B12 (pg/mL) Deficiency, PTH (pg/mL) and regarding Hyper-Parathyroidism, there was statistically significant difference between the two studied groups. there was a higher significant difference in OAGB with biliopancreatic limb length 200 cm than OAGB with biliopancreatic limb length 150 cm regarding Cholesterol and Triglycerides remission.

Conclusion
Results showed significant differences in Vit D3, Ferritin, albumin, calcium and Vit B12 deficiencies and Hyper-Parathyroidism. OAGB with biliopancreatic limb length 150 cm was as effective in weight loss and duration of DM, but had a higher significant difference in cholesterol and triglycerides remission.
Evaluation of Management and Outcome of Blunt Liver Trauma in Pediatrics and Adults
Authors: Wagdy Hesham Hasan Hasan , Abdelrahman Ahmed Hamed , Bersy Mohamed Aly Mahmoud , Abdelaal Hamza Mohamed Mahmoud 
Published: November 2024

Abstract

Background
The options for the management of blunt hepatic trauma in adults and children are nonoperative management, adjuncts of conservative management such as angioembolization, and open surgery.

Objective
To describe and compare the management strategies and outcomes of blunt liver trauma in pediatrics and adults over a specified period of time in Ain Shams University hospitals.

Patients and Methods
A retrospective analytical comparative study conducted at Ain Shams University Hospitals during the period from August 2022 to September 2023. 53 cases of admitted blunt liver injuries were included: 34 in the pediatric age group and 19 in the adult group.

Results
Outcome of conservative management was very promising regarding resolution and fewer rate of complications in both groups. However, Adjuncts of conservative management (angioembolization and image- guided drainage) were crucial in some patients managed conservatively and needed more often in the adult group.

Conclusion
Our study highlights significant differences in the management and outcomes of blunt liver trauma between pediatric and adult patients. Despite similarities in the mode of trauma, pediatric patients generally experienced less severe liver injuries and had higher success rates with conservative management compared to adults. Operative interventions and blood transfusion requirements were more common in adults, reflecting the higher incidence of high- grade injuries and active bleeding in this group. While the incidence of complications did not differ significantly, clinical outcomes were better in pediatric patients, with all experiencing complete resolution. These findings underscore the importance of tailored treatment approaches based on age and injury severity to optimize outcomes in blunt liver trauma.
A Prospective Randomized Comparative Study Comparing Clipping versus Thermal Ablation in Thoracoscopic Sympathectomy for Treatment of Hyperhidrosis
Authors: Monem Rizk Mohamed Abd El , Shoka Ahmed Adel , Samee Hassab Allah Mahmoud Adel Abdel 
Published: November 2024

Abstract

Background
Hyperhidrosis can be defined as a pathologic condition characterized by excessive sweating beyond the body’s physiological needs to maintain its temperature within an adequate range.

Aim of the Work
The aim of this work is to Compare Clipping Versus Thermal Ablation in Thoracoscopic Sympathectomy according to the effectiveness, recurrence, and reversibility for Treatment of hyperhidrosis.

Patients and Methods
A randomized comparative prospective study was conducted in general and vascular surgery departments in Ain Shams University Hospital and Nasser institute hospital for research and treatment. The study included 20 patients diagnosed with primary hyperhidrosis either palmer and/or axillary.

Results
In our study the operative time in group A ranged from 55 – 81 minutes with mean time of 68.00 ± 8.78 minutes, While in group B, Time ranged from 45 – 70 minutes with mean time of 55.20 ± 8.59 minutes and that difference was statistically significant (P=0.004), despite that the difference between the operative time of the 2 groups was statistically significant, yet it was only about 12 minutes. The previous results indicated high success rate for both procedures and that there is no statistically significant difference between the two techniques regarding the efficacy, yet the clipping technique offered the theoretical reversibility. In our study no patients requested reversal of the effect even those who suffered from postoperative compensatory hyperhidrosis and all patients were satisfied with the result of the procedure.

Conclusion
Our study found that there is no statistically significant difference between the clipping and the cautery technique regarding operative time, rate of complication, compensatory hyperhidrosis, patient satisfaction and success rate, Yet the clipping technique has the potential theoritical reversibility in case of severe compensatory hyperhidrosis developed.
Comparative Study between Endovenous Radiofrequency Ablation and Conventional Surgery of Primary Varicose Veins of Lower Limbs
Authors: El-Ahmady Rania , Abdelmoaty Karim Fahmy , Gamil Zekry Mina , Shahin Mostafa Hany Mokhtar 
Published: November 2024

Abstract

Background
Varicose veins are the main manifestations of chronic venous disease (CVD), and present as dilated and elongated incompetent superficial veins in the lower limbs. The most common method of treatment for this condition is an open surgery proposed by W. Keller 110 years ago. Radio- Frequency ablation (RFA) was proved to be effective in the treatment in many randomized controlled trials.

Aim of the Work
to throw light and compare Radio-Frequency Ablation to conventional surgery in treating primary varicose veins in lower limbs.

Patients and Methods
This prospective study included 30 patients, who were treated for symptomatic varicose veins of the lower limbs divided into two groups. In first one, 15 patients underwent open surgery (the surgery group), while in the other, 15 patients received the Radio- Frequency Ablation (the RF group). The patients were invited to follow-up evaluations at first and second weeks then one and six months after the surgery.

Results
VCSS scores at one month were better in the RFA group (median VCSS scores 1 (0–2) vs. 4 (3 – 5), p &lt; 0.0001). Patients in the RFA group experienced less postoperative pain (p &lt; .00163). In addition, patients in the RFA group managed to return to work and normal activities sooner than those in the surgery group (p &lt; 0.0001). No statistically significant differences were found between groups for overall satisfaction, rate of complications except hematoma which was higher in surgery group.

Conclusion
Both treatment techniques yielded similar results in terms of efficacy, complications and overall patient satisfaction. However, early postoperative results in the RF group were superior to those of patients in the surgery group.