bluuebunny/crossref_metadata_2025_split huggingface dataset:
The study of histological changes of the arterial vascular structure after hyaluronidase exposure
Authors: Wattanakrai Penpun , Jurairattanaporn Natthachat , Rojhirunsakool Salinee , Visessiri Yingluck , Suwanchinda Atchima , Thanasarnaksorn Wilai 
Published: August 2018

AbstractBackgroundHyaluronic acid (HA) filler injection is commonly used for soft tissue augmentation. Uncommon but serious complication from filler injection is vascular occlusion. Hyaluronidase enzyme can be used to dissolve HA filler. Evidence demonstrates that hyaluronidase can penetrate through vessel wall after incubation. However, studies regarding effects of hyaluronidase on vessel wall after intraluminal injection are limited. The objective of this study is to evaluate histological changes of postmortem arteries after intravascular injection of hyaluronidase enzyme.MethodsThis was an ex vivo experiment including arterial specimens from four cadavers which recently deceased within 24 hours. All vessels were examined at baseline and then were divided into two groups. The first was the control group treated with normal saline and the second hyaluronidase‐treated group was intra‐luminally injected with hyaluronidase enzyme (1500 IU/mL). Gross and histological examination was performed at baseline, 30‐minutes and 4 hours after.ResultsGross examination of vessels revealed no significant difference at baseline, 30 minutes and 4 hours after injection in both groups. Histological examinations at baseline and 30 minutes after injection revealed viable endothelial cells in both experimental and NSS‐control group. At 4 hours after hyaluronidase injection, two of the four arterial specimens had degeneration of endothelial cell, and one artery showed separation of tunica intima from tunica media.ConclusionThere were endothelial injuries in the arterial specimens after intravascular concentrated hyaluronidase injection.
Literature review of the adverse events associated with botulinum toxin injection for the masseter muscle hypertrophy
Authors: Yeh Yu‐Ting , Peng Jui‐Hui , Peng Hsien‐Li Peter 
Published: August 2018

AbstractBackgroundMasseteric hypertrophy is a benign condition characterized by the enlargement of the masseter muscles. A square‐shaped jawline due to masseter muscle prominence or hypertrophy is one of the general characteristics of the Asian face, making it a frequent target for esthetic treatment requests. While the application of botulinum toxin on the masseter muscle is an off‐label use, it is very popular in Asian countries. However, comprehensive reviews of the complications associated with this procedure remain limited in scope.ObjectivesThe goal of this study is to help physicians achieve a comprehensive understanding of the complications associated with neuromodulator injection over the masseter muscle via a thorough literature review.MethodsA literature search was performed on the PubMed/MEDLINE, Google Scholar, and Science Direct databases using the search terms botulinum toxin, masseter hypertrophy, masseteric hypertrophy, and/or masseter hyperplasia. Literature from January 1994 to February 2018 was deemed to be allegeable for inclusion and analysis. All available prospective and retrospective studies, case series, case reports, and expert reviews were included, with an emphasis on types of complications, incidence rate, onset time, recovery time, and product used. Articles that do not mention side effects, complications, or adverse events were excluded.ResultsThirty‐six articles were found, covering type, incidence rate, and clinical course of the complications. These studies were summarized into tabular form for easy reference and comparison.ConclusionBotulinum toxin masseter injections are commonly performed procedures with good results and safety profiles. The majority of complications appeared within 2‐4 weeks of injection and disappeared within 12 weeks. Despite the temporary nature of these complications, they often decrease patient satisfaction and confidence, so physicians should familiarize themselves with the regional anatomy and injection safety zones.
The posterior temporal supraSMAS minimally invasive lifting technique using soft‐tissue fillers
Authors: Suwanchinda Atchima , Webb Katherine L. , Rudolph Christina , Hladik Casey , Custozzo Amanda , Muste Justin , Schalet Grant , Hamade Hassan , Smith Michael P. , Frank Konstantin , Patel Ashit , Cotofana Sebastian 
Published: August 2018

AbstractBackgroundTo investigate the effectiveness of the posterior temporal supraSMAS minimally invasive lifting technique and compared it to experiments performed in fresh human body donors by applying skin vector displacement measurement technology.Materials and methodsA total of 15 patients (14 females/1 male) with a mean age of 37.1 ± 9.4 years and a mean body mass index of 21.4 ± 3.3 kg/m2 were included into this observational analysis. The injection procedure was additionally performed in 2 male and 1 female fresh body donors with a mean age of 85.67 ± 9.7 years and a mean body mass index of 23.83 ± 4.7 kg/m2. Different grades of skin laxity, variable amounts of product, and the application with and without subcision were tested and measured via three‐dimensional reconstructions and surface displacement vectors using Vectra software with VAM module.ResultsEsthetic outcome was rated by an independent professional observer and by the patient immediately after the treatment (76.67% ± 17.6% vs 66.67% ± 18.1%) (P = 0.001) and after 1 month (80.00% ± 14.0% vs 75.00% ± 21.1%) (P = 0.19). Skin laxity, subcision, and the application of more than 1.0 cc per side resulted in our experimental setting in a smaller magnitude of skin displacement vectors indicating a reduced lifting effect.ConclusionThe posterior temporal supraSMAS minimally invasive lifting procedure seems to be a valid technique to treat temporal volume loss and to reduce the signs of age‐related changes in the middle and lower face, ie “marionett line” and jowl deformity.
Italian consensus report on the aesthetic use of onabotulinum toxin A
Authors: Bertossi Dario , Cavallini Maurizio , Cirillo Pierfrancesco , Piero Fundarò Salvatore , Quartucci Sandro , Sciuto Chantal , Tonini Davide , Trocchi Gloria , Signorini Massimo 
Published: August 2018

SummaryBackgroundThe aesthetic treatment of facial and neck wrinkles with botulinum toxin is constantly increasing, thus making it necessary to collect procedures guidelines for the use of botulinum toxin in the treatment of wrinkles and/or cosmetic defects.MethodsA group of nine Italian doctors, plastic and maxillo‐facial surgeons, dermatologists and aesthetic physicians, experts in face and neck aesthetic treatments with onabotulinum toxin A, discussed on procedures used in their clinical practice. From the data collected and discussed by the board, some recommendations on aesthetic treatment with onabotulinum toxin A were developed.ResultsRecommendations have been made on pretreatment, reconstitution of onabotulinum toxin A, as well as on treatment procedures, in terms of injection sites and total dose of onabotulinum toxin A for the following indications: glabellar lines, crown’s feet lines, forehead lines, eyebrow shaping, lower orbicularis oculi hypertrophy, bunny lines, sagging nasal tip, gummy smile, masseter hypertrophy, perioral lines, marionette lines, hypertonic mentalis, and platysma bands.ConclusionsThe use of onabotulinum toxin A in the aesthetic field requires careful initial assessment of the patient in its complexity and individuality. Moreover, this treatment needs the use of standardized procedures to achieve the effectiveness and safety of onabotulinum toxin A in clinical practice.
Care of veterans in a non‐veteran health administration hospital: What is the status of nursing practice after continuing education?
Authors: Maiocco Gina , Stroupe Lya M. , Rhoades Anthea , Vance Billie 
Published: August 2018

AbstractAims and objectivesTo identify how civilian nurses are caring for military veterans following mandatory continuing education on veterans’ mental health needs and to describe challenges nurses are facing in provision of that care.BackgroundVeterans and military personnel experience mental health conditions at a high rate and are increasingly receiving care in civilian healthcare facilities. Nonmilitary providers may not be prepared to address this population's challenging needs. Military culture may influence the presentation of mental health conditions; thus, critical assessment points by nonmilitary medical personnel may be missed. Education is touted internationally as a means to address deficits, but research is lacking to support that statement.MethodsAdhering to research reporting guidelines, 115 of a proposed 322 civilian nurses in a tertiary hospital volunteered to complete a one‐time online survey that contained quantitative and demographic questions. Forty of 115 nurses went on to complete the qualitative query. Descriptive statistics summarised quantitative results, and constant comparative analysis was applied to qualitative responses for theme identification.ResultsThe study was stopped early due to reports of violence from veterans upon nurses. Results showed continuing education did not change documentation of military status. Following mandatory continuing education, civilian nurses continued to describe uncertainty in how to adapt care, on how to interact with veterans and in how to deal with violence.ConclusionThe status of care to veterans remains insufficient, but nurses are asking critical questions on how to update practice. Additional support and research in the clinical setting is needed to promote a safe caring environment.Relevance to clinical practiceContinuing education alone may not advance care of the veteran. A multipronged approach to include mandatory documentation of military status and coaching of providers by those experienced with the military way of life may be used to augment staff preparedness.
Medication adherence assessment practices in dialysis settings: A survey of renal nurses’ perceptions
Authors: Ghimire Saurav , Banks Colin , Jose Matthew D. , Castelino Ronald L. , Zaidi Syed Tabish R. 
Published: August 2018

AbstractAims and objectivesTo measure renal nurses’ perceptions on assessing medication adherence in patients undergoing dialysis.BackgroundRenal nurses play a vital role in caring for patients undergoing dialysis. Despite the high prevalence of medication nonadherence in chronic dialysis patients, little is known about renal nurses’ perceptions and current adherence assessment practices.DesignA cross‐sectional survey.MethodsParticipants completed an online survey between March–May 2016. Five psychometric scales were used to measure perception on prevalence and contributors of nonadherence, effective methods of assessment, barriers to assessment and confidence to assess adherence. The survey also captured current adherence assessment practices using a 4‐point graded response (1 = do not practice at all to 4 = practice for every patient).ResultsA total of 113 dialysis nurses completed the survey. The majority agreed that patients in their unit are nonadherent to their medicines (74.5%, n = 82; median = 8). Most nurses agreed that having dedicated professionals conducting medication history interviews can be effective in identifying nonadherence (88.9%, n = 96; median = 8). Objective assessment through blood results was the most frequently used method to determine nonadherence (83.2%, n = 89), with little attention being paid to patients’ self‐reports of adherence (55.1%, n = 59). Time constraints, administrative support and patients’ disinterest in discussing medication‐related issues with the nurses were perceived as barriers to assessing adherence.ConclusionsPatient self‐reported measures to assess adherence were underutilised by the renal nurses, whereas objective blood monitoring was routinely used. Overcoming dialysis nurses’ work‐related barriers may facilitate the effective monitoring and promotion of medication adherence in chronic dialysis patients.Relevance to clinical practiceResults from this study emphasise the need for proper assessment of dialysis patient's medication‐taking behaviour during routine dialysis to ensure the benefits of prescribed therapies.
Association between comfort and needs of ICU patients’ family members: A cross‐sectional study
Authors: Meneguin Silmara , de Souza Matos Ticiane Dionízio , Miot Helio Amante , Pollo Camila Fernandes 
Published: August 2018

AbstractAims and objectiveTo identify the family members’ level of comfort and needs and to analyse the sociodemographic/clinical variables that influence this association.BackgroundThe needs of family members are important considerations in intensive care units. In this context, the needs will be assessed in five dimensions: information, safety, proximity, support and comfort. This study describes the association between comfort and needs of ICU patients’ family members.DesignCross‐sectional study developed at the adult ICU of a hospital within the state of São Paulo, in the period from July–September 2016.MethodsWe used the Critical Care Family Needs Inventory (INEFTI) Portuguese version and the comfort scale for critical care patient relatives (ECONF).ResultsIn relation to INEFTI, the relatives assigned high importance to the needs (Median = 167), but not all of them satisfied (Median = 151). The comfort was low (Median = 3.6), and support was the most affected domain (Median = 2.78). The multivariate analysis indicated variables that influenced the comfort: marital status (β = 0.80; p < 0.01), disease severity (β = 0.03; p = 0.04), female sex (β = 0.34; p = 0.01), highest educational attainment (β = 0.37; p < 0.01), employment status (β = 0.81; p < 0.01) and kinship (β = 0.34; p < 0.01). Concerning the INEFTI scores, only age was statistically significant for importance (β = 0.16; p < 0.01) and satisfaction (β = −0.29; p = 0.04) of the family members’ needs. In the multiple correspondence analysis, different proximities were identified for the variables comfort and needs. Greater ECONF scores were associated with family members with a higher educational degree, whose patients were stable, who attributed high levels of importance to the needs and who were housewives.ConclusionsFamily members have needs that are considered important but not fully met. No direct correspondence between comfort and family needs was identified.Relevance to clinical practiceIn view of the lack of studies involving family members’ comfort and needs, we believe that these results can guide nursing proposals focused on the family members, in line with the associations found among different variables that influenced the results.
A modified developmental care bundle reduces pain and stress in preterm infants undergoing examinations for retinopathy of prematurity: A randomised controlled trial
Authors: Chuang Ling‐Ju , Wang Shih‐Hao , Ma Mi‐Chia , Lin Chia‐Ni , Chen Chih‐Ling , Huang Mei‐Chih 
Published: August 2018

AbstractAims and objectivesTo determine the comparative efficacy of developmental care versus standard care for reducing pain and stress in preterm infants during examinations for retinopathy of prematurity (ROP).BackgroundROP examinations are routinely performed in neonatal intensive care units to detect these lesions. Pain scores recorded during and after eye examinations have revealed physiological and behavioural manifestations of pain and stress.DesignA randomised crossover trial was conducted.MethodsFourteen preterm infants were evaluated. The modified developmental care bundle included environmental modifications, positioning and containment, oxygen supplementation, interaction and approach and cue‐based individual care, which were applied before, during and after the ROP examination. The primary outcomes were obtained from pain and stress scores using the premature infant pain profile‐revised (PIPP‐R) and a behavioural evaluation. The secondary outcomes were recovery time to the baseline of the vital signs and oxygen saturation.ResultsStatistical significances were found in the care type comparison (p = 0.013), time comparison (p < 0.001) and type‐by‐time interaction (p = 0.005) in the PIPP‐R, and also in the care type comparison (p < 0.001), time comparison (p < 0.001) and type‐by‐time interaction (p = 0.001) in the behavioural evaluation scores using a generalised estimating equation (GEE) analysis. Recovery time for the developmental care (N = 13, mean = 8.6 ± 11.5 min, 95% CI = 1.68–15.57) was significantly shorter than for the standard care (N = 11, mean = 25.5 ± 20.8 min, 95% CI = 11.45–39.46), which was found to be statistically significant according to the Wilcoxon signed‐rank test (N = 11, p = 0.003).ConclusionsA bundled developmental care intervention significantly reduced pain and stress responses and the time needed for infants to recover their physiological status following the procedure.Relevance to clinical practiceSince the results show the benefits of developmental care in an ROP examination, it can be the practical evidence basis by which to develop a standard of procedure or guideline for clinical practice.
Perceived added value of a decision support App for formal caregivers in community‐based dementia care
Authors: Thoma‐Lürken Theresa , Lexis Monique A. S. , Bleijlevens Michel H. C. , Hamers Jan P. H. 
Published: August 2018

AbstractAims and objectivesTo gain insight into the perceived added value of a decision support App for district nurses and case managers intended to support a problem assessment and the provision of advices on possible solutions to facilitate ageing in place of people with dementia, and to investigate how they would implement the App in daily practice.BackgroundDistrict nurses and case managers play an important role in facilitating ageing in place of people with dementia (PwD). Detecting practical problems preventing PwD from living at home and advising on possible solutions is complex and challenging tasks for nurses and case managers. To support them with these tasks, a decision support App was developed.MethodsA qualitative study using semi‐structured interviews was conducted. A photo‐elicitation method and an interview guide were used to structure the interviews. The data were analysed according to the principles of content analysis.ResultsIn five interviews with seven district nurses and case managers, the added value was described in terms of five themes: (a) providing a broader/better overview of possible solutions; (b) providing a guideline/checklist for problem assessment and advice on solutions; (c) supporting an in‐depth problem assessment; (d) being a support tool for unexperienced case managers/district nurses; and (e) providing up‐to‐date information. The participants regarded the App as complementary to their current work procedure, which they would use in a flexible manner at different stages in the care continuum.ConclusionsThe participants valued both parts, the problem assessment and the overview of possible solutions. An important requisite for the usage would be that the content is continuously updated. Before implementation of the App can be recommended, an evaluation of its effectiveness regarding decision‐making should be conducted.Relevance to clinical practiceThis study underpins the need of nurses and case managers for decision support with regard to problem assessment and providing advices on possible solutions to facilitate ageing in place of PwD. There results also show the importance of listening to users experience and their perceived added value of decision support tools as this helps to explain the lack of statistically significant effects on quantitative outcome measure in contrast to a high willingness to use the App in a previous study.
Anomalies and News
Authors: ENGELBERG JOSEPH , MCLEAN R. DAVID , PONTIFF JEFFREY 
Published: August 2018

ABSTRACTUsing a sample of 97 stock return anomalies, we find that anomaly returns are 50% higher on corporate news days and six times higher on earnings announcement days. These results could be explained by dynamic risk, mispricing due to biased expectations, or data mining. We develop and conduct several unique tests to differentiate between these three explanations. Our results are most consistent with the idea that anomaly returns are driven by biased expectations, which are at least partly corrected upon news arrival.
Currency Risk Factors in a Recursive Multicountry Economy
Authors: COLACITO RIC , CROCE MARIANO M. , GAVAZZONI FEDERICO , READY ROBERT 
Published: August 2018

ABSTRACTFocusing on the 10 most traded currencies, we provide empirical evidence regarding a significant heterogeneous exposure to global growth news shocks. We incorporate this empirical fact in a frictionless risk‐sharing model with recursive preferences, multiple countries, and multiple consumption goods whose supply features both global and local short‐ and long‐run shocks. Since news shocks are priced, heterogeneous exposure to long‐lasting global growth shocks results in a relevant reallocation of international resources and currency adjustments. Our unified framework replicates the properties of the HML‐FX and HML‐NFA carry‐trade strategies studied by Lustig, Roussanov, and Verdelhan and Della Corte, Riddiough, and Sarno.
Comparison of the Fit of Lithium Disilicate Crowns made from Conventional, Digital, or Conventional/Digital Techniques
Authors: Al Hamad Khaled Q. , Al Rashdan Bashar A. , Al Omari Wael M. , Baba Nadim Z. 
Published: August 2018

AbstractPurposeTo evaluate the fit of single crowns fabricated using conventional, digital, or cast digitization methods.Materials and MethodsOne subject with a peg‐shaped maxillary lateral incisor was selected in this study. Tooth preparation for an all‐ceramic crown was performed and 10 conventional poly(vinyl siloxane) impressions, and 10 digital impressions using an intraoral scanner were made. Each working cast was scanned using a laboratory scanner and an intraoral scanner. Four groups were tested Group 1: conventional impressions. Group 2: cast laboratory scans. Group 3: cast scans using intraoral scanner. Group 4: direct intraoral scans. For group 1, heat‐pressed glass ceramic crowns (IPS e.max Press) were fabricated using casts produced from the conventional impressions. For groups 2‐4, crowns were milled using ceramic blocks (IPS e.max CAD). Ten crowns were fabricated for each group. Marginal and internal gaps were measured using a replica technique. Replicas were sectioned mesiodistally and buccolingually and were observed under a stereomicroscope. Three measurements were selected for each cut: occlusal, axial, and marginal. Statistical analysis was performed using two‐way ANOVA and Tukey HSD tests.ResultsFor each replica, 6 measurements were made for the mesiodistal and the same for the buccolingual cuts, producing 12 measurement points per crown (4 measurements for marginal, 4 for axial, 4 for occlusal), 120 measurements for each group (40 measurements for marginal, 40 for axial, 40 for occlusal), and 480 measurements in total. Two‐way ANOVA revealed location to be a significant factor (p = 0.001). No significant differences among groups (p = 0.456), and no interactions between groups and locations (p = 0.221) were found. Means for the occlusal site were significantly larger than other sites in most group combinations, while the difference between the marginal and axial sites was not significant. No significant differences among groups were found for each measurement. The marginal gaps ranged from 125.46 ± 25.39 μm for group 3 to 135.59 ± 24.07 μm for group 4. The smallest axial mean was in group 1 (98.10 ± 18.77 μm), and the largest was 127.25 ± 19.79 μm in group 4. The smallest occlusal mean was in group 2 (166.53 ± 36.51 μm), and the largest occlusal mean was in group 3 (203.32 ± 80.24 μm).ConclusionsCeramic crowns, which were made using all‐digital approach or cast digitization by a laboratory or intraoral scanner had comparable fit to those produced by conventional approach.