bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unconventional secretory pathway activation restores hair cell mechanotransduction in an USH3A model
Authors: Gopal Suhasini R. , Lee Yvonne T. , Stepanyan Ruben , McDermott Brian M. , Alagramam Kumar N. 
Published: May 2019

SignificanceWe report on a zebrafish model of hearing loss in Usher syndrome type IIIA caused by pathogenic variant c.144T>G (p.N48K) in the clarin1 gene (CLRN1). We expressedCLRN1c.144T>Gin wild-type or clarin1 knockout zebrafish and then probed these animals with genetic or pharmaceutical small-molecular agents. Our findings revealed that the CLRN1N48Kprotein is transported to the hair cell bundle via an unconventional secretory pathway, and activation of this pathway using artemisinin, an antimalarial drug, enhanced CLRN1N48Klevels in hair cell bundles and rescued their functions. Our report demonstrates a paradigm to evaluate the functional consequence of human pathogenic variants in hair cells in vivo and reveals artemisinin’s therapeutic potential to mitigate sensory deficits inCLRN1c.144T>Gand other endoplasmic reticulum aggregation disorders.
Circumventing kinetics in biogeochemical modeling
Authors: Louca Stilianos , Scranton Mary I. , Taylor Gordon T. , Astor Yrene M. , Crowe Sean A. , Doebeli Michael 
Published: May 2019

Significance
Predicting biochemical processes driven by microbes in the environment remains challenging, because the “kinetic” parameters conventionally used to predict reaction rates are usually poorly known. Here we mathematically show that in poorly mixed systems, such as stagnant waters, bulk biochemical reaction rates can become limited by the slow transport of substrates across space and essentially independent of kinetic parameters. We demonstrate our arguments for a large and heavily studied ocean basin, where we accurately predict the microbially driven fluxes of various substances, across a depth range of hundreds of meters. Our work opens up avenues for predicting ecosystem processes without knowledge of kinetic parameters and without laborious chemical profile measurements.
Approaching the typology and diachrony of morphological reversals
Authors: Igartua Iván 
Published: May 2019

Abstract
Inverse marking in inflectional morphology represents a particular type of mismatch between morphological form and syntactic or semantic function. This kind of morpheme interchange has been found in several languages thus far, but it is not usually included in morphological studies. There have been significant advances in recent times regarding the synchronic description and theoretical assessment of morphological reversals, but the diachronic treatment of this set of phenomena is at most in its incipient stage. Despite the overall scarcity of historical data on the rise of inverse marking patterns, there is, nonetheless, a certain amount of evidence that allows for an understanding of the dynamics of morphological polarity in a diachronic perspective. This paper first provides a revised typology of morphological reversals and then examines two processes of change leading to the appearance of inverse encoding patterns in two inflectional systems (declensional paradigms in Old French and the feature of number in Upper Sorbian). Although differing in important respects (such as the extent to which they can be considered reversals), both innovations demonstrate some of the motives, mechanisms, and functional principles underlying the emergence of inverse marking patterns in inflectional morphology.
Word order as grammaticalised semiotic systems
Authors: Heltoft Lars 
Published: May 2019

Abstract

Meillet (1921 [1912]: 147-48) briefly states that word order is grammatical and that word order change is an alternative way of grammaticalisation, a stance that has had few followers within mainstream grammaticalisation studies. In the context of Henning Andersen’s view of morphology and the principles of its analysis, I propose a typology of the ways word order can grammaticalise, i.e. organise in closed paradigms, built on the distinction between symbolic, indexical and iconic meaning.
Aspects of grammaticalization and reanalysis in the voice domain in the transition from Latin to early Italo-Romance
Authors: Cennamo Michela 
Published: May 2019

Abstract
This article discusses some aspects of the grammaticalization and reanalysis of lexical verbs as passive auxiliaries and light verbs in the passage from Latin to (Italo-)Romance, focussing on (i) the diachronic relationship between auxiliarization and light verbs, (ii) the direction of the changes and (iii) the pertinacity to change of light verbs. The light verb uses of the verbs under investigation (COME, BECOME), both in Late Latin and in some early Italo-Romance vernaculars, exhibit a different type of decategorialization and desemanticization compared with auxiliaries, attested later than their auxiliary function.
Name-calling
Authors: Janda Laura A. 
Published: May 2019

Abstract
Henning Andersen (2012) points out that the Russian “new Vocative” (e.g., мам! ‘mama!’, Саш! ‘Sasha!’) presents a series of unusual behaviors that set it apart from ordinary case marking. Andersen argues that the Vocative should not be considered a declensional word form of nouns. The Russian Vocative is certainly an uncommon linguistic category, but does this entail setting up a new transcategorial derivation? Similar restrictions are found in other markers that are generally recognized as case desinences. The pragmatic use of virile vs. deprecatory nominative plural markers in Polish and lexical and morphophonological restrictions on the “second Locative” in Russian. The restrictions found in the Vocative are certainly unusual, but no single one of them can be said to exclude a marker from being identified with a case, and one must ask what we gain by inaugurating new derivational types.
Spatial deictics in translation
Authors: Bartkutė Darija , Verikaitė-Gaigalienė Daiva 
Published: May 2019

AbstractRecent research on deictic elements has made extensive use of translation corpora to demonstrate that asymmetries between translational paradigms signal subtle contrasts from a systemic and pragmatic perspective. The purpose of the present study is to identify translation correspondences of the English spatial demonstrativethisin Lithuanian and to discuss the contrastive features within the analytical framework of translational explicitation and implicitation. The results indicate that in the prototypical situational usage there is a high degree of correspondence betweenthisand its Lithuanian translation, while textual uses demonstrate low formal equivalence. A tendency to implicitate stems from the null subject construction and object ellipsis in Lithuanian and is also a result of the availability of facultative deictic words in Lithuanian. The apparent systemic difference between the deictic systems of English and Lithuanian indicates a tendency towards optional implicitation and stylistic variation in literary translation.
In silico
crops and multi-omic approaches to meet agricultural challenges.
Authors: Challa G. S. , Marshall-Colón A. 
Published: May 2019

Abstract

For decades, plant geneticists have attempted to link crop genes to phenotypes of interest. Advanced technologies in molecular biology, biochemistry and high-performance computing have provided unprecedented depth of knowledge about biological systems, and have accelerated molecular breeding and bioengineering of crop species. Single-omic level technologies that explore genomes, transcriptomes, proteomes and metabolomes have led to gene discovery and have revealed important signalling and regulatory mechanisms that influence crop response to the environment. Data from individual biological scales have been used in mathematical models to predict how crops will respond to untested environmental conditions. However, many of these models are empirical and lack predictive capability that can extrapolate beyond the conditions used to optimize the model. There is a need to move beyond modelling at single-scales to achieve integrative, multiscale modelling that takes full advantage of our understanding of molecular mechanisms and the wealth of genomewide data that has been generated over the last three decades. In this review, we survey the most recent literature exploring the collection and analysis of multi-omic data, and provide examples of attempts to integrate these data in various ways. It is apparent that integrative and multiscale modelling improve crop model prediction accuracy, and it is anticipated that the movement towards
in silico
crops will aid in the development of crop ideotypes that can thrive under challenging environmental conditions.
A review of aetiology and risk factors affecting sow mortality.
Authors: Supakorn China , Moeller G. , Stock J. D. , Johnson A. K. , Stalder K. J. 
Published: May 2019

Abstract
Sow-mortality rates in the US breeding herds have been increasing in recent years. Based on reports in the scientific literature, sow-mortality rates started increasing by the mid- to late-1990s. This reality continues to be documented through database evaluation and reports from herd managers and producers. These trends are a clear challenge to herd veterinarians and producers in the swine industry in the USA and many other countries around the world. Sow-mortality challenges are complex issues with multiple risk factors. This review covers reported incidences of increasing sow mortality, as well as aetiologies and risk factors associated with sow mortality occurring in the modern lean-type sow. Gastro-intestinal, heart and locomotive problems, cystitis-pyelonephritis (inflammation of the urinary bladder and kidney), reproductive failure, prolapses and additional disorders are consistently reported as common aetiologies for sow mortality. Information on related risk factors such as population, sow housing, reproductive stage and health status lead efforts to define and resolve sow mortality. Increasing sow mortality could well be taken as an indictment of modern production systems, of the genetically improved sows, or the knowledge and actions of animal caretakers. Prompt resolution of sow mortality is of critical importance and is a public expectation with respect to the ethical treatment and care of production food animals.
Hamstring rate of torque development is more affected than maximal voluntary contraction after a professional soccer match
Authors: Grazioli Rafael , Lopez Pedro , Andersen Lars L. , Machado Carlos Leonardo Figueiredo , Pinto Matheus Daros , Cadore Eduardo Lusa , Pinto Ronei Silveira 
Published: May 2019

AbstractMatch‐induced fatigue of knee muscle strength and agonist‐antagonist strength‐ratios may affect both performance and risk of injury in soccer players. Once explosive tasks are imperative in soccer as well as hamstring strain injuries occur during high‐velocity moments, rapid force capacity of this muscle group is especially important. This study evaluated the effect of match‐induced fatigue on knee muscle strength and strength‐ratio parameters after a single professional soccer match. Male professional soccer players (n = 16; 24.2 ± 3.9 years) were tested before and after a soccer match (56.2 ± 22.6 min of playing) for knee flexors (hamstring) and extensors (quadriceps) isometric peak torque (MVC) and rate of torque development (RTD) – as well as the hamstring‐to‐quadriceps ratio (H:Q) – at 30° of knee flexion. Knee injuries often occur at this joint angle, which is common in sprinting, pivoting, sidecutting, and jumping. Match‐induced fatigue caused a left shift in the knee extensors torque‐time curve with no significant change in both early (i.e. 0–50 ms) and late (i.e. 0–200 ms) RTD, and a right shift in the knee flexors torque‐time curve with a decrease in early RTD (∼16%, p = .029) and late RTD (∼11%, p = .011). Knee extensors and knee flexors peak torque remained unchanged (p > .05). Early RTD H:Q decreased by∼24% (p = .027), while late RTD H:Q and MVC H:Q remained unchanged (p > .05). In conclusion, match‐induced fatigue impaired the ability to rapidly produce force at an angle where injuries are most susceptible to occur. Important information is missed if only the traditional H:Q is considered.
Successive lag cluster consensus on multi-agent systems via delay-dependent impulsive control*
Authors: Qiu Xiao-Fen , Zhang Yin-Xing , Li Ke-Zan 
Published: May 2019

Abstract
We introduce a new consensus pattern, named a successive lag cluster consensus (SLCC), which is a generalized pattern of successive lag consensus (SLC). By applying delay-dependent impulsive control, the SLCC of first-order and second-order multi-agent systems is discussed. Furthermore, based on graph theory and stability theory, some sufficient conditions for the stability of SLCC on multi-agent systems are obtained. Finally, several numerical examples are given to verify the correctness of our theoretical results.
Molecule opacities of

X

2

Σ

+

,

A

2

Π

, and

B

2

Σ

+

states of CS+
*
Authors: Lin Xiao-He , Liang Gui-Ying , Wang Jian-Guo , Peng Yi-Geng , Shao Bin , Li Rui , Wu Yong 
Published: May 2019

Abstract
Carbon sulfide cation (CS+) plays a dominant role in some astrophysical atmosphere environments. In this work, the rovibrational transition lines are computed for the lowest three electronic states, in which the internally contracted multireference configuration interaction approach (MRCI) with Davison size-extensivity correction (+Q) is employed to calculate the potential curves and dipole moments, and then the vibrational energies and spectroscopic constants are extracted. The Frank–Condon factors are calculated for the bands of

X

2

Σ

+

−

A

2

Π

and

X

2

Σ

+

−

B

2

Σ

+

systems, and the band of

X

2

Σ

+

−

A

2

Π

is in good agreement with the available experimental results. Transition dipole moments and the radiative lifetimes of the low-lying three states are evaluated. The opacities of the CS+ molecule are computed at different temperatures under the pressure of 100 atms. It is found that as temperature increases, the band systems associated with different transitions for the three states become dim because of the increased population on the vibrational states and excited electronic states at high temperature.
Rydberg electromagnetically induced transparency and Autler–Townes splitting in a weak radio-frequency electric field*
Authors: Hao Liping , Xue Yongmei , Fan Jiabei , Jiao Yuechun , Zhao Jianming , Jia Suotang 
Published: May 2019

Abstract
We utilize an electromagnetically induced transparency (EIT) of a three-level cascade system involving Rydberg state in a room-temperature cell, formed with a cesium 6S1/2–6P3/2–66S1/2 scheme, to investigate the Autler–Townes (AT) splitting resulting from a 15.21-GHz radio-frequency (RF) field that couples the

|
66

S

1

/

2

〉
→
|
65

P

1

/

2

〉

Rydberg transition. The radio-frequency electric field induced AT splitting, γ
AT, is defined as the peak-to-peak distance of an EIT-AT spectrum. The dependence of AT splitting γ
AT on the probe and coupling Rabi frequency, Ωp and Ωc, is investigated. It is found that the EIT-AT splitting strongly depends on the EIT linewidth that is related to the probe and coupling Rabi frequency in a weak RF-field regime. Using a narrow linewidth EIT spectrum would decrease the uncertainty of the RF field measurements. This work provides new experimental evidence for the theoretical framework in [J. Appl. Phys.
121, 233106 (2017)].
Effect of laser polarization on strong-field ionization and fragmentation of nitrous oxide molecules*
Authors: Wang Rui , Zhang Shi-Wen , Liu Yang , Sun Tian , Lv Hang , Xu Hai-Feng 
Published: May 2019

Abstract
Ionization of molecules in femtosecond laser fields is the most fundamental and important step of various strong-field physical processes. In this study, we experimentally investigate strong field ionization of linear N2O molecules using a time-of-flight mass spectrometer in 800-nm laser fields. Yields of the parent ion and different fragment ions are measured as a function of laser intensity in the range of 2.0×1013 W/cm2 to 3.6×1014 W/cm2. We also investigate the dependence of strong field ionization and dissociation of N2O on laser ellipticity and polarization direction. The significant role of laser induced electron re-collision in the formation of highly charged fragment ions is proved. The physical mechanism of strong field ionization and fragmentation is discussed, based on our experimental results.
Optically manipulated nanomechanics of semiconductor nanowires*
Authors: Song Chenzhi , Yang Shize , Li Xiaomin , Li Xiao , Feng Ji , Pan Anlian , Wang Wenlong , Xu Zhi , Bai Xuedong 
Published: May 2019

Abstract
Opto–electromechanical coupling at the nanoscale is an important topic in new scientific studies and technical applications. In this work, the optically manipulated electromechanical behaviors of individual cadmium sulfide (CdS) nanowires are investigated by a customer-built optical holder inside transmission electron microscope, wherein in situ electromechanical resonance took place in conjunction with photo excitation. It is found that the natural resonance frequency of the nanowire under illumination becomes considerably lower than that under darkness. This redshift effect is closely related to the wavelength of the applied light and the diameter of the nanowires. Density functional theory (DFT) calculation shows that the photoexcitation leads to the softening of CdS nanowires and thus the redshift of natural frequency, which is in agreement with the experimental results.
Influence of warm eddies on sound propagation in the Gulf of Mexico*
Authors: Xiao Yao , Li Zhenglin , Li Jun , Liu Jiaqi , G Sabra Karim 
Published: May 2019

Abstract
An automatic detection method is employed to identify and track eddies in the Gulf of Mexico. The physical parameters of the eddies, such as lifespan, radius, and distribution position are first examined and used to determine the spatio–temporal evolution of a strong warm eddy separated from the Mexico current. Then, the influence of this strong warm eddy on sound propagation during its lifespan are comprehensively analyzed with the parabolic equation and explained by using the normal mode and ray theories. Additionally, the influence of mesoscale eddies on the redistribution of total depth-integrated energy among the normal modes in the deep water is also discussed. The variation of arrival angle is investigated to explain the spreading acoustic energy caused by eddies. Overall, the results show that warm eddies can change the propagation paths and cause the convergence zone to broaden and approach the sound source. Moreover, the warm eddy can disperse sound energy and cause the total depth-integrated energy to incline to a lower normal mode. Throughout the whole of these three periods (eddy generating, eddy maturing, and eddy terminating), the fluctuation in the transmission loss is up to 30 dB (depending on the relative location of eddy center to the source).
A passive source ranging method based on the frequency warping transform of the vertical intensity flux in shallow water*
Authors: Qi Yu-Bo , Zhou Shi-Hong , Yu Meng-Xiao , Du Shu-Yuan , Sun Mei , Zhang Ren-He 
Published: May 2019

Abstract
The phase of cross-correlation function of two different normal modes contains source range information, which can be extracted by warping transform due to the dispersive characteristics of the shallow water waveguide. The autocorrelation function of the received pressure or particle velocity contains both modal autocorrelation component (MAC) and modal cross-correlation component (MCC), with the former part usually treated as interference for source ranging. Because the real part of the vertical intensity flux (RPVIF) only contains MCC, a passive impulsive source ranging method based on the frequency warping transform of RPVIF with a single vector receiver in shallow water is presented. Using a waveguide-invariant-based frequency warping operator, the cross-correlation components of two different modes in the vertical intensity flux are warped into separable impulsive sequences, the time delays of which are subsequently used for source ranging. The advantages of source ranging based on warping the vertical intensity flux compared with warping the pressure autocorrelation function are pointed out, and the experiment results are also presented.
Structure instability-induced high dielectric properties in [001]-oriented 0.68Pb(Mg1/3Nb2/3)O3–0.33PbTiO3 crystals*
Authors: Li Xiao-Juan , Fan Xing , Xi Zeng-Zhe , Liu Peng , Long Wei , Fang Pin-Yang , Nan Rui-Hua 
Published: May 2019

Abstract
The structure evolution and origin of ultrahigh dielectric properties have been investigated in the low temperature range from 300 K to 5 K for [001]-oriented 0.68Pb(Mg1/3Nb2/3)O3–0.33PbTiO3 (PMN–33PT) crystal. The experimental results reveal that a short-range ordered monoclinic MA is the dominant phase at ambient temperature. As the temperature drops below 270 K, the MA transforms into monoclinic MC, and the MC remains stable until 5 K. Although no phase transition occurs from 5 K to 245 K, polar nanoregions (PNRs) display visible changes. The instability of PNRs is suggested as responsible for the low temperature relaxation. The ultrahigh dielectric constant at room temperature is associated with the instability of local structure and phase transition. Our research provides an insight into the design of high-performance ferroelectric materials.
Tuning the intensity statistics of random speckle patterns*
Authors: Meng Fan , Zhao Yue , Zhang Yun-Zuo , Huo Lei 
Published: May 2019

Abstract
Speckle patterns are a fundamental tool in a variety of physical and optical applications. Here, we investigate a method of precisely tuning the intensity statistics of random speckle patterns into a desirable pattern that possesses the same spatial correlation length and similar statistics distribution. This tuning mechanism relies on the derivation of the transform function and transmission matrix, which achieves different contrasts while maintaining the same average value or energy level. The statistics properties of the generated speckle patterns are further investigated by analyzing the standard deviation under different fitting parameters. Precisely tuning the intensity statistics of random speckle patterns could be useful for both fundamental research and practical applications, such as microscopy, imaging, and optical manipulation.
Unified description of thermal behaviors by macroscopic growth laws
Authors: Castorina P , Castorina S , Lanteri D 
Published: May 2019

Abstract
Complex systems, in many different scientific sectors, show coarse-grain properties with simple growth laws with respect to fundamental microscopic algorithms. The known classification schemes of the growth laws refer to time evolution of biological and technical systems. We propose to apply the previous classifications to phenomenological analysis of thermal systems with a cross-fertilization among different sectors. As an example, the Fermi–Dirac distribution function and the electrical activation in implanted silicon carbide are discussed.