bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compress global, dilate local: Intentional binding in action–outcome alternations
Authors: Imaizumi Shu , Tanno Yoshihiko , Imamizu Hiroshi 
Published: December 2018

AbstractIntentional binding refers to subjective temporal attraction between an action and its outcome. However, the nature of intentional binding in multiple actions remains unclear. We examined intentional binding in alternated action–outcome dyads. Participants actively or passively pressed a key, followed by a tone, and they again pressed the key; resulting in four keypress–tone dyads in a trial. Participants reproduced the duration of alternated keypress–tone dyads or the temporal interval between a dyad embedded in the alternations. The reproduced duration was shorter in the active than in the passive condition, suggesting the intentional binding in action–outcome alternations. In contrast, the reproduced interval between a dyad was longer in the active condition and did not correlate with the reproduced duration. These results suggest that subjective time during actions relies not only on an internal clock but also on postdictive biases that are switched based on what we recall.
Distinguishing among complex evolutionary models using unphased whole-genome data through Approximate Bayesian Computation
Authors: Ghirotto Silvia , Vizzari Maria Teresa , Tassi Francesca , Barbujani Guido , Benazzo Andrea 
Published: December 2018

AbstractInferring past demographic histories is crucial in population genetics, and the amount of complete genomes now available should in principle facilitate this inference. In practice, however, the available inferential methods suffer from severe limitations. Although hundreds complete genomes can be simultaneously analyzed, complex demographic processes can easily exceed computational constraints, and the procedures to evaluate the reliability of the estimates contribute to increase the computational effort. Here we present an Approximate Bayesian Computation (ABC) framework, based on the Random Forest algorithm, to infer complex past population processes using complete genomes. To do this, we propose to summarize the data by the full genomic distribution of the four mutually exclusive categories of segregating sites (FDSS), a statistic fast to compute from unphased genome data. We constructed an efficient ABC pipeline and tested how accurately it allows one to recognize the true model among models of increasing complexity, using simulated data and taking into account different sampling strategies in terms of number of individuals analyzed, number and size of the genetic loci considered. We tested the power of theFDSSto be informative about even complex evolutionary histories and compared the results with those obtained summarizing the data through the unfolded Site Frequency Spectrum, thus highlighting for both statistics the experimental conditions maximizing the inferential power. Finally, we analyzed two datasets, testing models (a) on the dispersal of anatomically modern humans out of Africa and (b) the evolutionary relationships of the three species of Orangutan inhabiting Borneo and Sumatra.
Distinct molecular etiologies of male and female hepatocellular carcinoma
Authors: Natri Heini M. , Wilson Melissa A. , Buetow Kenneth 
Published: December 2018

AbstractSex-differences in cancer occurrence and mortality are evident across tumor types; men exhibit higher rates of incidence and often poorer responses to treatment. Targeted approaches to the treatment of tumors that account for these sex-differences require the characterization and understanding of the fundamental biological mechanisms that differentiate them. Hepatocellular Carcinoma (HCC) is the second leading cause of cancer death worldwide, with the incidence rapidly rising. HCC exhibits a male-bias in occurrence and mortality, but previous studies have failed to explore the sex-specific dysregulation of gene expression in HCC. Here, we characterize the sex-shared and sex-specific regulatory changes in HCC tumors in the TCGA LIHC cohort. By using a sex-specific differential expression analysis of tumor and tumor-adjacent samples, we uncovered etiologically relevant genes and pathways differentiating male and female HCC. While both sexes exhibited activation of pathways related to apoptosis and cell cycle, males and females differed in the activation of several signaling pathways, with females showing PPAR pathway enrichment while males showed PI3K, 305 PI3K/AKT, FGFR, EGFR, NGF, GF1R, Rap1, DAP12, and IL-2 signaling pathway enrichment. Using eQTL analyses, we discovered germline variants with differential effects on tumor gene expression between the sexes. 24.3% of the discovered eQTLs exhibit differential effects between the sexes, illustrating the substantial role of sex in modifying the effects of eQTLs in HCC. The genes that showed sex-specific dysregulation in tumors and those that harbored a sex-specific eQTL converge in clinically relevant pathways, suggesting that the molecular etiologies of male and female HCC are partially driven by differential genetic effects on gene expression. Overall, our results provide new insight into the role of inherited genetic regulation of transcription in modulating sex-differences in HCC etiology and provide a framework for future studies on sex-biased cancers.
Taylor series approximation and unbiased GM(1,1) based hybrid statistical approach for forecasting daily gold price demands
Authors: Rathnayaka R.M. Kapila Tharanga , Seneviratna D.M.K.N. 
Published: December 2018

Purpose
The time series analysis is an essential methodology which comprises the tools for analyzing the time series data to identify the meaningful characteristics for making future ad-judgments. The purpose of this paper is to propose a Taylor series approximation and unbiased GM(1,1) based new hybrid statistical approach (HTS_UGM(1,1)) for forecasting time series data under the poor, incomplete and uncertain information systems in a short period of time manner.

Design/methodology/approach
The gray forecasting is a dynamical methodology which can be classified into different categories based on their respective functions. The new proposed methodology is made up of three different methodologies including the first-order unbiased GM(1,1), Markov chain and Taylor approximation. In addition to that, two different traditional gray operational mechanisms include GM(1,1) and unbiased GM(1,1) used as the comparisons. The main objective of this study is to forecast gold price demands in a short-term manner based on the data which were taken from the Central Bank of Sri Lanka from October 2017 to December 2017.

Findings
The error analysis results suggested that the new proposed HTS_UGM(1,1) is highly accurate (less than 10 percent) with lowest RMSE error values in a one head as well as weakly forecasting’s than separate gray forecasting methodologies.

Originality/value
The findings suggested that the new proposed hybrid approach is more suitable and effective way for forecasting time series indices than separate time series forecasting methodologies in a short-term manner.
Multicultural teaching efficacy and cultural intelligence of teachers
Authors: Kang Hye-Seung (Theresa) , Kim Eun-Jee , Park Sunyoung 
Published: December 2018

Purpose
The purpose of this paper is to examine the impact of learning goal orientation and training readiness on teachers’ multicultural teaching efficacy and cultural intelligence.

Design/methodology/approach
A total of 182 responses from secondary schools in midwest and southern areas of the USA were analyzed using the hierarchical multiple regression.

Findings
The findings indicated that learning goal orientation positively influenced both teachers’ multicultural teaching efficacy and cultural intelligence, while training readiness did not significantly affect them. In addition, teachers’ multicultural teaching efficacy positively influenced their cultural intelligence.

Research limitations/implications
The study implied that high-level learning goal orientation can contribute to enhance multicultural teaching efficacy and cultural intelligence for teachers.

Practical implications
By conducting needs analysis of participants in advance, trainers can reflect what teachers want and need when designing and implementing a workshop. In addition, trainers could prepare for interventions to improve the participation rate of multicultural workshops and the quality of existing workshop programs.

Originality/value
This study is important in that it will help to develop culturally sensitive workshop/training programs that can prepare teachers for diverse classroom environments and face potential issues that may arise.
A look into the past and future: theories within supply chain management, marketing and management
Authors: Gligor David , Bozkurt Siddik , Russo Ivan , Omar Ayman 
Published: December 2018

PurposeAlthough supply chain scholars have acknowledged the fundamental disruptive changes experienced by today’s supply chains and the ensuing novelty of the research problems worthy of investigation, they have primarily relied on a limited number of theories to help explain the phenomena of interest. The purpose of this paper is to use a systematic literature review to address this gap and propose additional theories that supply chain researchers can use to help address novel supply chain phenomena, such as those caused by technological disruptions.Design/methodology/approachThe authors use a systematic literature review to examine the studies published over the last 10 years in six of the top supply chain management journals (411 articles) and six of the top marketing and management journals (1,214 articles).FindingsFirst, the findings show that 15 theories have been relied upon by over 95 per cent of the studies within supply chain management that use formal theories. Second, the authors identify the most frequently used theories within marketing and management (217 theories). Third, as space limitations make it impossible to offer a rich description of each of the 217 theories, the authors identify 30 theories that they considered to be the most salient to supply chain research and suggest areas where supply chain scholars can apply these theoretical lenses.Originality/valueThe research effort allowed the authors to map the current use of theories within the field to gain a better understanding of what other theories could augment the body of theories used within supply chain management. Thus, the current study is a “one stop shop” that supply chain scholars can consult when in a quandary about what theoretical lens to utilize.
The effect of vacancy on the interfacial diffusion in Cu/Sn lead-free solder joints
Authors: Yang Li , Xiaoyan Li , Yao Peng 
Published: December 2018

Purpose
The purpose of this paper is to investigate the diffusion behaviors of different atoms at the Cu/Cu3Sn interface and the vacancy formation energy, diffusion energy barrier and vacancy diffusion activation energy.

Design/methodology/approach
The diffusion behaviors of different atoms at the Cu/Cu3Sn interface are analyzed, and the vacancy formation energy, diffusion energy barrier and vacancy diffusion activation energy are obtained using molecular dynamics simulation. The nudged elastic band method is used to evaluate diffusion energy barrier for Cu/Cu3Sn system.

Findings
It is found that the vacancies in the Cu/Cu3Sn interface promote the interfacial diffusion, and the formation energy of Cu vacancy in the Cu crystal is larger than that in Cu3Sn crystal. In addition, the formation energies of Cu1 vacancy and Cu2 vacancy are close to each other in Cu3Sn crystal, and they are all less than the formation energy of Sn vacancy. Furthermore, the vacancy diffusion barrier and vacancy diffusion activation energy of the Cu/Cu3Sn interface are calculated, and the results show that the vacancy diffusion activation energy of Sn was higher than that of Cu. Finally, by comparison of diffusion activation energies of different diffusion mechanisms, Cu→Cu1vac is the most possible migration path at all temperatures.

Originality/value
It is concluded that the vacancies in Cu/Cu3Sn interface promote interfacial diffusion, and the activation energy of vacancy diffusion in most diffusion mechanisms decreases with the increase of temperature.
The Transforming Care agenda: admissions and discharges in two English learning disability assessment and treatment units
Authors: Washington Francine , Bull Samantha , Woodrow Ceri 
Published: December 2018

Purpose
The purpose of this paper is to evaluate whether two regional intellectual disability (ID) assessment and treatment (A&T) units in England were meeting the recommended length of stay stipulated by the Learning Disability Professional Senate, in line with the Transforming Care (TC) agenda. A secondary purpose of the study was to evaluate the reasons for admissions and delayed discharges in order to inform how to reduce these.

Design/methodology/approach
A retrospective evaluation of 85 admissions across two A&T units was conducted over a three-year period (2013–2016) following publication of the TC agenda.

Findings
There were 85 admissions compared to 71 discharges. Of the 85 admissions, 11 were readmissions. The most common factors thought necessary to prevent admission were early support for care providers or alternative service provision. There were barriers to discharge in over half of admissions; the main reason was a lack of suitable service provision.

Practical implications
The study suggests that providing specific support or training to care providers could prevent (re)admission and ensure shorter admissions. Further research to establish reasons for the reported lack of suitable providers would be beneficial.

Originality/value
This study provides current admission and discharge rates for regional A&T units, as recommended by the TC national guidance. It also provides potential reasons underlying preventable admissions and delayed discharges and therefore indicates what might be necessary to prevent admissions and reduce the length of inpatient stays for people with ID and/or autism.
Positive Behavioural Support as an alternative to medication
Authors: Lee Ruth M. , Rhodes Jennifer A. , Gerrard David 
Published: December 2018

Purpose
The purpose of this paper is to demonstrate how Positive Behavioural Support (PBS) can be used as an alternative to psychotropic medication to improve the quality of life of an individual with a learning disability and behaviour described as challenging.

Design/methodology/approach
A single case design was utilised. A unique PBS stopping over medication of people with a learning disability, autism or both (STOMP) clinic model was developed and PBS was used in line with National Institute for Health and Care Excellence (NICE) guidance. This included functional behavioural assessment, to support understanding of the reasons behind behaviour described as challenging, and a gradual medication reduction.

Findings
This case study found that antipsychotic medication used to manage behaviour that challenges could be safely reduced and individual quality of life increased when PBS was used as an alternative.

Originality/value
STOMP is a project supported by NHS England aimed at reducing the inappropriate prescribing of psychotropic medication to manage behaviour that challenges. NICE guidance recommends that behaviour should be more appropriately understood through PBS. More research is needed to demonstrate how the two work together for safe medication reduction and improved quality of life.
Vitamin D status in Thai dermatologists and working‐age Thai population
Authors: Rajatanavin Natta , Kanokrungsee Silada , Aekplakorn Wichai 
Published: December 2018

AbstractThis study aimed to determine the prevalence of vitamin D insufficiency among Thai dermatologists compared with the general working‐age population in Bangkok. A cross‐sectional study was conducted in healthy Thai physicians who had at least 1 years’ experience in dermatology practise and a subsample of the general Thai population from the Fourth National Health Survey. Serum 25‐hydroxyvitamin D (25[OH]D), a combination of 25(OH)D2 and 25(OH)D3, levels in both groups were measured using liquid chromatography coupled with mass spectrometry. The majority of dermatologists were of Fitzpatrick skin type III (n = 61, 61.3%) or IV (n = 32, 33.3%). The mean serum 25(OH)D and 25(OH)D3 levels were 18.9 and 18.2 ng/mL, respectively, whereas the corresponding levels in the general population were 26.5 and 25.8 ng/mL. None of the dermatologist had serum 25(OH)D sufficiency (>30 ng/mL), 38 (38.78%) had vitamin D insufficiency (20–30 ng/mL) and 60 (61.22%) had vitamin D deficiency (<20 ng/mL). The frequency of vitamin D deficiency in dermatologists was significantly higher than in the general population (61.2% vs 19.2%, P < 0.001). Ninety percent of dermatologists used sunscreen daily and spent time mostly indoors. Dermatologists used physical sun‐protection more than half of the time when outdoors, for example, a book or paper as a sunshade (70.3%), an umbrella (48.4%), a long‐sleeved shirt (20.4%) or a hat (9.7%). In conclusion, dermatologists showed a remarkably high prevalence of vitamin D deficiency which may be due to inadequate exposure to sunlight, regular use of sunscreen and practicing various sun‐protection activities.
Attitudes, Perceptions, and Preferences of Individuals from Temuco (Chile) About Denture Marking
Authors: Rojas‐Torres Javier , Navarro‐Cáceres Pablo , Fonseca Gabriel M. 
Published: December 2018

AbstractDenture marking (DM) helps identify edentulous people with different methods. Analyzing perceptions and attitudes of denture wearers would enable understanding of the practical aspects, an analysis still absent in South America. Fifty‐three individual candidates for removable dentures were instructed on disaster victim identification (DVI) and the usefulness of DM for this purpose. They were physically shown eight DM systems and a questionnaire to which they responded by highlighting preferences in those systems. Although 98.11% did not know that dentures could be marked, only 9.43% denied interest in some type of DM. The 90.57% would mark their dentures with some system, preferring the inclusion of QR codes or a micro SIM card. The proven weaknesses of DVI and propensity for disaster mean this community in Chile is an opportunity to implement DM systems. Obstacles may come not from patients but from their dentists, educational institutions, or a lack of public policies.
Methamphetamine presentations to an emergency department: Management and complications
Authors: Isoardi Katherine Z , Ayles Sarah F , Harris Keith , Finch Clare J , Page Colin B 
Published: December 2018

AbstractObjectiveThere is little recent published data characterising methamphetamine intoxication. The present study aims to describe the clinical effects, management, complications and disposition of patients with methamphetamine exposure.MethodsThis is a retrospective review of patients presenting with methamphetamine intoxication to an ED in 2016. All presentations were extracted from a relational database and each medical record reviewed. Demographics, clinical features, complications and disposition were extracted.ResultsThere were 378 presentations of 329 patients (234 men [71%]), median age 31 years (range 16–68 years). The most common clinical effect was acute behavioural disturbance, occurring in 295 (78%) presentations. This was successfully managed with oral sedation alone in 180 (61%) patients, with the remainder receiving parenteral sedation. Other effects included tachycardia in 212 (56%), hypertension in 160 (42%) and hyperthermia in 17 (5%) presentations. No anti‐hypertensives were given. One patient was actively cooled. Complications included 21 (30%) presentations with rhabdomyolysis and 41 (13%) presentations with acute kidney injury. There were two seizures, three intracranial bleeds and one myocardial infarction. The majority (317 [84%]) of patients were managed solely within the ED. The median length of stay was 14 h. There were 41 (11%) mental health admissions. Two deaths occurred: one following an out‐of‐hospital cardiac arrest and the other a subarachnoid haemorrhage.ConclusionThe main toxicity seen with methamphetamines is acute behavioural disturbance, which is managed well with sedation. Complications, apart from rhabdomyolysis and acute kidney injury, are rare. Most patients are managed within the ED and discharged home.
Characterization of Heat‐Induced Water Adsorption of Sea Cucumber Body Wall
Authors: Dong Xiuping , Liu Wentao , Song Xue , Lin Xiaoyu , Yu Da , Yu Chenxu , Zhu Beiwei 
Published: December 2018

AbstractDifferent heating conditions could change water absorption capacity of sea cucumbers body wall (SCBW), and subsequently affect the sensory quality of the rehydrated sea cucumbers. In this study, fresh SCBWs were boiled for 30, 60, 90, 120, 150, 180 min, respectively. The boiled SCBWs were then soaked in deionized water for 48 hr. The changes in water absorption ratio (Wabs), water holding capacity, water distribution, texture and ultrastructure of the SCBW were investigated. With increasing cooking time (from 30 to 180 min) the water absorption capacity is significantly enhanced (from 1.84 times to 3.37 times). The absorbed water was found to exist inside the SCBW in two forms, physisorbed water, which entered the SCBW via diffusion and could be easily removed, and associated water, which formed association with the SCBW structure, evidenced by the difference in mobility determined by low field nuclear magnetic resonance (LF‐NMR) spectroscopy. Study of the microstructure of the SCBW showed that the collagen fibers in the SCBW gradually depolymerized and degraded, resulting in the formation of inter‐fiber pores and gaps which became internal space that could accommodate more and more water as the cooking time increased. This water was mainly physisorbed with high mobility. The texture characteristics of the SCBW negatively correlated with the accumulation of physiosorbed water. These findings suggest that proper control of heating time could be critical in determining the sensory/eating quality of sea cucumbers.Practical ApplicationDifferent heating conditions allows sea cucumbers to have different water absorption capacity during the subsequent soaking process, which could greatly affect sea cucumber sensory quality. Understanding the effects of heating on the water absorption characteristics and texture characteristics of sea cucumber body wall will provide knowledge basis and guidelines to optimize the processing parameters for the emerging ready‐to‐eat sea cucumber industry