bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preventive Behavioral Health Programs in Primary Care: A Systematic Review
Authors: Brown Courtney M. , Raglin Bignall Whitney J. , Ammerman Robert T. 
Published: May 2018

CONTEXT:Early childhood is a critical period for socioemotional development. Primary care is a promising setting for behavioral health programs.OBJECTIVES:To identify gaps in the literature on effectiveness and readiness for scale-up of behavioral health programs in primary care.DATA SOURCES:PubMed, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Embase, Evidence-Based Medicine Reviews, and Scopus databases were searched for articles published in English in the past 15 years. Search terms included terms to describe intervention content, setting, target population, and names of specific programs known to fit inclusion criteria.STUDY SELECTION:Inclusion criteria were: (1) enrolled children 0 to 5 years old, (2) primary care setting, (3) measured parenting or child behavior outcomes, and (4) clinical trial, quasi-experimental trial, pilot study, or pre-post design.DATA EXTRACTION:Data were abstracted from 44 studies. The rigor of individual studies and evidence base as a whole were compared with the Society of Prevention Research’s standards for efficacy, effectiveness, and scale-up research.RESULTS:Gaps in the literature include: study findings do not always support hypotheses about interventions’ mechanisms, trust in primary care as a mediator has not been sufficiently studied, it is unclear to which target populations study findings can be applied, parent participation remains an important challenge, and the long-term impact requires further evaluation.LIMITATIONS:Potential limitations include publication bias, selective reporting within studies, and an incomplete search.CONCLUSIONS:Targeting gaps in the literature could enhance understanding of the efficacy, effectiveness, and readiness for scale-up of these programs.
The Biomarker S100B and Mild Traumatic Brain Injury: A Meta-analysis
Authors: Oris Charlotte , Pereira Bruno , Durif Julie , Simon-Pimmel Jeanne , Castellani Christoph , Manzano Sergio , Sapin Vincent , Bouvier Damien 
Published: May 2018

CONTEXT:
The usefulness of S100B has been noted as a biomarker in the management of mild traumatic brain injury (mTBI) in adults. However, S100B efficacy as a biomarker in children has previously been relatively unclear.

OBJECTIVE:
A meta-analysis is conducted to assess the prognostic value of S100B in predicting intracerebral lesions in children after mTBI.

DATA SOURCES:
Medline, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, Scopus, and Google Scholar.

STUDY SELECTION:
Studies including children suffering mTBI who underwent S100B measurement and computed tomography (CT) scans were included.

DATA EXTRACTION:
Of 1030 articles screened, 8 studies met the inclusion criteria.

RESULTS:
The overall pooled sensitivity and specificity were 100% (95% confidence interval [CI]: 98%–100%) and 34% (95% CI: 30%–38%), respectively. A second analysis was based on the collection of 373 individual data points from 4 studies. Sensitivity and specificity results, obtained from reference ranges in children with a sampling time &lt;3 hours posttrauma, were 97% (95% CI: 84.2%–99.9%) and 37.5% (95% CI: 28.8%–46.8%), respectively. Only 1 child had a low S100B level and a positive CT scan result without clinically important traumatic brain injury.

LIMITATIONS:
Only patients undergoing both a CT scan and S100B testing were selected for evaluation.

CONCLUSIONS:
S100B serum analysis as a part of the clinical routine could significantly reduce the number of CT scans performed on children with mTBI. Sampling should take place within 3 hours of trauma. Cutoff levels should be based on pediatric reference ranges.
Visualizing Embodied Research: Dance Dramaturgy and Animated Infographic Films
Authors: Jürgens Stephan , Fernandes Carla 
Published: May 2018

This video essay introduces a new form of visualization of embodied research, called “animated infographic films.” In these films, techniques like motion graphics, 3D modeling and camera animation are used to invite the viewer to enter the choreographer’s studio. Here we invite you to come into the digitally re-created studio of João Fiadeiro and engage kinesthetically and empathetically with selected examples of his compositional and dramaturgical strategies. These infographic films are based on the results of a study on three signature solo works from different stages of Fiadeiro’s choreographic work. The research has been carried out within the framework of the BlackBox Arts and Cognition Project.
A comparative analysis between ring annuloplasty and de vega annuloplasty in functional tricuspid regurgitation
Authors: Bhagwan Jai , Guha Soumya , Gupta Anubhav , Padhy Ajit Kumar , Grover Vijay , Gupta Vijay Kumar 
Published: May 2018

Background: Tricuspid valve disease frequently accompanies left side valve disease. Surgical correction of significant functional TR at the time of left side valve surgery is recommended. The current study was under taken to assess the early impact of ring annuloplasty and De Vega annuloplasty techniques in functional significant TR in a predominantly rheumatic population.Methods: Between January 2010 and January 2014, a total 80 patients underwent surgery for functional tricuspid valve disease. Retrospective data analysis was done. The patient selection criteria were as per the institutional protocol (for all functional severe TR and moderate TR with Tricuspid Index > 21mm/m2) based on preoperative TTE (Trans-thoracic Echocardiography) findings and the type of procedure was the surgeon’s decision on table. Techniques routinely involved in the repair procedures included tricuspid prosthetic ring Annuloplasty (MC3) and De Vega suture annuloplasty. Postoperatively all the patient had routine TTE before hospital discharge (considered as immediate post op period). Follow up was present till 6 months post-operatively (in the form of another TTE and clinical data sheet) at the time of data collection for this study. Results: There was no statistically significant difference in residual significant TR when ring annuloplasty was compared to De Vega repair. There was significant improvement in NYHA status after both ring and De Vega annuloplasty. Conclusions: Present study shows similar results with both the techniques of TV repair when applied to functionally significant TR in a pre-dominantly rheumatic population.
Clinical predictors of hypoxemia in children with WHO classified pneumonia
Authors: Kushwah Meenakshi S. , Verma Yogendra S. , Gaur Ajay 
Published: May 2018

Background: In developing countries were health providers have to rely on signs and symptoms to identify hypoxemia in pneumonia and start oxygen therapy, this study was therefore conducted to assess the prevalence and predictors of hypoxemia with the hypothesis to design a severity score for hypoxemia in children with pneumonia.Methods: This prospective observational study was carried out at the paediatric emergency department of Gajra Raja Medical College, Gwalior, on children of age 1-60 months admitted with respiratory illness categorised on basis of “Revised WHO Classification of Pneumonia”. Various demographic and clinical features were noted. Oxygen saturation was measured via a pulse oximeter. Hypoxemia was deﬁned as SpO2 <90%. Statistical analysis was done.Results: Of the 200 children studied, 67 (33.5%) had hypoxemia. Fever, breathing difficulty, and crepitations were the most sensitive, while inability to feed, cyanosis, grunting, head nodding and impaired consciousness were the most speciﬁc indicators for hypoxemia. Fever, lethargy, inability to feed, nasal flaring, grunting, impaired consciousness and cyanosis were found significant (p value<0.05). Combinations of tachypnea with nasal flaring, grunting, cyanosis, and retractions with grunting were also found significant in predicting hypoxemia. Combinations of tachypnea with grunting (90.2%) and cyanosis (94.7%) were found highly specific. Using these combinations, a new hypoxemia scoring system was designed to predict the severity of hypoxemia.Conclusions: Study suggested that combination of clinical signs may be utilized as markers for hypoxemia in conditions where pulse-oximeter is not available.
Prospective study of tubercular co-infection in HIV infected patients in VIMSAR, Burla, Sambalpur, Odisha, India
Authors: Bariha P. K. , Pujari U. P. , Kullu B. K. , Thakur A. 
Published: May 2018

Background: Tuberculosis is the most common opportunistic infection in HIV positive patient. This is a major challenge faced by HIV positive patient. Methods: This study was carried out at Medicine Department and ART Centre, VIMSAR, Burla to know the epidemiology and clinical profile of HIV and TB co-infection. This is a prospective study in which all adult patients attending to our hospital for period of one year with HIV-TB co infection are enrolled. There were 269 patients. The clinical parameters are studied after all detailed history and clinical examination. The diagnosis of Tuberculosis was made by relevant investigation like Sputum AFB, Chest X-ray, CSF Study, CT Scan, Pleural Fluid Study, Ascitic fluid study etc.Results: The results indicate majority of the patients out of 211 patients 74 (82.52%), were male 34(16.35%)were female and TGTS were-3(1.42%). Age group mostly affected were 26-35 years (38.1%) and 36-45 years (38.1 %). Extra-pulmonary TB constituted 56.28% and Pulmonary TB-43.72%. 41.99% completed anti-TB treatment and mortality was 12.99%. Mean CD4 count at the time of diagnosis-218iu/l; and patients with low CD4 cell count at the time of diagnosis had high mortality.Conclusions: Extra-pulmonary TB is predominant among HIV TB co-infection and the working-class population affected more than the rest TB Meningitis and Disseminated TB are associated with a bad prognosis when compare to other forms of TB. A low CD4 count at the time of Tuberculosis diagnosis is associated with a higher mortality and early suspicion diagnosis of tuberculosis and early initiation of ATT in HIV patients reduces mortality and morbidity significantly.
Goal Orientation and Academic Performance in Adult Distance Education
Authors: Neroni Joyce , Meijs Celeste , Leontjevas Ruslan , Kirschner Paul A. , De Groot Renate H.M. 
Published: May 2018

Research has shown the importance of goal orientation in predicting academic performance for children, adolescents, and college students in traditional educational settings. Studies on this relationship within adult distance education, however, are lacking. To fill this gap, the present study was conducted to investigate the relationship between goal orientation and academic performance in adult distance learners. A sample of N = 1128 distance university students (age 18-75 years) filled out an online questionnaire. Their exam grades were collected from the files of the Open University of the Netherlands (OUNL). A mixed model regression showed performance approach goal orientation to be a positive predictor of academic performance, whereas performance avoidance and work avoidance were negative predictors of academic performance. Non-significant results were found for mastery approach as well as for mastery avoidance. Implications of these results are discussed.
FAIR AND EQUITABLE TREATMENT STANDARD IN NTERNATIONAL INVESTMENT AGREEMENTS
Authors: . Sefriani 
Published: May 2018

<pre><span lang="EN-US">In the last five years, the number of investors who suit against host state in the international arbitration forum increased significantly. Almost all lawsuits used fair and equitable treatment (FET) standard which has been violated by the host state. Most of international investment agreements including those that were made by Indonesia contain FET standard clauses. However, there are no definitions related to this standard. This condition potentially raises a very wide interpretation of the standard. The problem formulations in this article are how the history of FET is, where its position in international investment law is and what elements of FET standard are. The results show that the FET standard has existed since Havana Charter followed by various FCN, BIT and other international investment agreements. FET standard can be categorized as customary international, legally binding on all countries regardless their national law. Although there is no universal approval regarding the scope of FET standard, the writings which have been published and the arbitral tribunal decision mentions that those elements are legitimate expectation; due process; denial of justice; rule of law; non-discrimination; transparency; consistency, good faith, and reasonableness.</span></pre><pre><span lang="EN-US"> </span></pre>
Medicinal Chemistry of Potassium Channel Modulators: An Update of Recent Progress (2011-2017)
Authors: Vyas Vivek K. , Parikh Palak , Ramani Jonali , Ghate Manjunath 
Published: May 2018

Background:
Potassium (K+) channels participate in many physiological processes,
cardiac function, cell proliferation, neuronal signaling, muscle contractility, immune function,
hormone secretion, osmotic pressure, changes in gene expression, and are involved in critical
biological functions, and in a variety of diseases. Potassium channels represent a large family
of tetrameric membrane proteins. Potassium channels activation reduces excitability, whereas
channel inhibition increases excitability.

Objective:
Small molecule K+ channel activators and inhibitors interact with voltage-gated,
inward rectifying, and two-pore tandem potassium channels. Due to their involvement in biological
functions, and in a variety of diseases, small molecules as potassium channel modulators
have received great scientific attention.

Methods: :
In this review, we have compiled the literature, patents and patent applications
(2011 to 2017) related to different chemical classes of potassium channel openers and blockers
as therapeutic agents for the treatment of various diseases. Many different chemical classes of
selective small molecule have emerged as potassium channel modulators over the past years.

Conclusion:
This review discussed the current understanding of medicinal chemistry research
in the field of potassium channel modulators to update the key advances in this field.
Synthesis and Cytotoxicity Studies on Novel Piperazinylacetamides
Authors: Bobtaina Eman , Gurdal Enise Ece , Durmaz Irem , Atalay Rengul Cetin , Yarim Mine 
Published: May 2018

Background:
In this study, nine novel compounds, bearing N-[2-(4-substituted
piperazine-1-yl)acetyl]-N’-[bis-(4-fluorophenyl)methyl]piperazine structures were synthesized.

Methods:
Their cytotoxic properties were evaluated in vitro by NCI-60 Sulforhodamine B
(SRB) assay against human cancer cell lines: Huh7 (hepatocellular), MCF7 (breast) and HCT116
(colorectal).

Results and Conclusion:
According to the activity data, most of the compounds are more cytotoxic
than 5-fluorouracil against Huh7 and HCT116 cancer cell lines.
Effect of Prestress Force on Natural Bending Frequency of External Prestressed Steel Beams
Authors: Bai-jian Tang , Fei Wang , Song Chen 
Published: May 2018

Introduction:
Natural bending frequencies of externally prestressed steel beam have certain sensitivity to prestress force, so they can be used to find the magnitude of prestress force.

Methods:
To answer the question if the existence of externally prestressed tendons increases or decreases the natural bending frequencies of a simply supported steel beam, the calculating formula for natural frequencies is deduced by using the energy method from the view point of prestress mechanism and further verified by the finite element method. Using this formula of universal property, the influence of prestress force, eccentricity and cross-sectional area of tendons on natural bending frequencies of prestressed steel beam is clearly revealed.

Results and Conclusion:
For external prestressed steel beams with straight tendons, their natural frequencies increase with the eccentricity and cross-sectional area of the prestressed tendon, and the eccentricity has a much larger effect on natural frequencies than the cross-sectional area does. The prestress force has no influence on the oven-order frequencies but decreases the odd-order frequencies. With the increasing order number, the prestress effect is much weaker than the effects caused by the eccentricity and cross-sectional area of the tendon.
مظاهر الانحراف التشريعي في القوانين الجنائية وأثره في الاستقرار القانوني
Authors: Hassan Mohammed R. 
Published: May 2018

تسعى هذه الدراسة إلى تسليط الضوء على المعايير و القواعد الواجب إتباعها عند وضع التشريعات الجنائية ، لان العديد من المفترضات يقتضي على المشرع تبنيها عند إنشاء القاعدة القانونية الجنائية و من بين هذه المعايير التشريع بناءً على ضرورة مجتمعية ملحة و مراعاة الاولويات المجتمعية عند التشريع . أضف الى ذلك مراعاة القسم العام من قانون العقوبات ممارسة عملية التجريم . و بعد التفحص في أغلب القوانين الجنائية الصادرة في الاقليم لاحظنا فقدان الاعتداد بهذه المعايير و هذا الامر ينعكس بطبيعة الحال على مدى نجاعة القاعدة القانونية ذاتها و الانصياع لها من قبل المخاطبين لها ، كما يجب أن لا نغفل ما يثيره هذا النوع من التشريع من خلق بلبلة و جدل في أوساط الجهات التي تتولى تطبيق القانون لان التجريم يجب ان تكون بحدود و وفق معايير غدت هذه المعايير اليوم جزءً من كل تشريع جنائي سليم و محق لأهدافه . و هذا ما سنستقصيه و نحدده عسى و لعل ان يكون بحثنا مرشداً و منهجاً للمشرع الجنائي عند سنه التشريعات الجنائية
Effects of different force magnitudes on corticotomy-assisted orthodontic tooth movement in rats
Authors: Kraiwattanapong Kriangkrai , Samruajbenjakun Bancha 
Published: May 2018

ABSTRACT

Objectives:
To investigate the effects of light and heavy forces with corticotomy on tooth movement rate, alveolar bone response, and root resorption in a rat model.

Materials and Methods:
The right and left sides of 40 male Wistar rats were randomly assigned using the split-mouth design to two groups: light force with corticotomy (LF) and heavy force with corticotomy (HF). Tooth movement was performed on the maxillary first molars using a nickel-titanium closed-coil spring delivering either 10 g (light force) or 50 g (heavy force). Tooth movement and alveolar bone response were assessed by micro–computed tomography (micro-CT) at day 0 as the baseline and on days 7, 14, 21, and 28. Root resorption was examined by histomorphometric analysis at day 28.

Results:
Micro-CT analysis showed a significantly greater tooth movement in the HF group at days 7 and 14 but no difference in bone volume fraction at any of the observed periods. Histomorphometric analysis found no significant difference in root resorption between the LF and HF groups at day 28.

Conclusions:
Heavy force with corticotomy increased tooth movement at days 7 and 14 but did not show any difference in alveolar bone change or root resorption.
Perceção, expressão e valorização das emoções das crianças na educação pré-escolar
Authors: Capelo Maria Regina Teixeira Ferreira , Varela John Miguel Costa , Serrano-Díaz Noemí 
Published: May 2018

A educação emocional é fundamental para a adaptação pessoal e social do indivíduo. Assim sendo, buscou-se por meio desta pesquisa adaptar a prova para avaliar a capacidade de perceber, expressar e valorizar emoções das crianças portuguesas na educação pré-escolar. Após equivalência semântica, operacional, conceptual e de itens, a prova foi respondida por 374 crianças. Os dados obtidos foram contrastados com critérios externos avaliados pelas representações das 26 educadoras de infância. Verificou-se maior número de acertos em relação à alegria e à tristeza na subescala perceção e expressão das emoções básicas com a escola privada a apresentar maior rendimento; que a perceção e valorização das emoções básicas aumenta em função da idade; que o género feminino apresenta maior performance na subescala perceção e valorização das emoções básicas; e relações significativas positivas entre as subescalas em análise e os critérios externos - adaptação, controlo, rendimento e aceitação, e correlações significativas negativas entre as subescalas e a conflitividade. A prova, embora em fase desenvolvimental, contribui para medir a adaptação pessoal e social das crianças portuguesas na etapa pré-escolar Palavras-chave: Perceção Emocional. Valorização Emocional. Avaliação da Perceção Emocional.
Percepções de estagiários da educação física sobre o estágio supervisionado na Educação Infantil
Authors: Isbarrola Jessica Almeida , Copetti Jaqueline 
Published: May 2018

A Educação Física (EF) é obrigatória em todas as fases da Educação Básica, entretanto na Educação Infantil (EI) não há obrigatoriedade de aulas ministradas por profissionais de EF. Mesmo com essa problemática o currículo das Licenciaturas proporciona o reconhecimento da realidade docente a partir dos estágios supervisionados curriculares (ECS). Esse estudo buscou analisar as percepções de estagiários de EF referentes às experiências positivas e negativas encontradas em seus ECS na EI, através de uma pesquisa documental e qualitativa. Os documentos utilizados neste estudo foram os relatórios finais do ECS na EI de discentes, de ambos os sexos, aprovados no primeiro semestre dos anos de 2015 (8 relatórios), 2016 (9 relatórios) e 2017 (11 relatórios), os quais realizaram este como o primeiro estágio. A técnica de análise utilizada para examinar os resultados foi a Análise de Conteúdo de Bardin. Os resultados foram analisados a partir de quatro categorias que identificaram 25 palavras-chave. Conforme a frequência apurada de cada palavra-chave as que tiveram maior frequência foram: Agitados (73); Participação dos alunos(156); e Controle da turma (37). A relação dessas palavras-chave permite concluir que as experiências classificam-se em negativas e positivas, contribuindo na formação acadêmica e pessoal de cada estagiário. Assim, concluiu-se que a interação entre Universidade e Escola abrange benefícios além da contribuição na formação acadêmica dos discentes, englobam novos conhecimentos e o desenvolvimento de todos os participantes das experiências dos estágios. Palavras-chave: Educação Física. Educação Infantil. Estágio Supervisionado.
Utilização de aplicativos gratuitos para atividade de campo no ensino de trigonometria no triângulo retângulo
Authors: Lopes Thiago Beirigo , Hardoim Edna Lopes 
Published: May 2018

As atividades de campo têm figurado como uma excelente estratégia para o ensino das ciências naturais. Ao imaginar que as atividades de campo também podem contribuir com o ensino de matemática, surge a questão de pesquisa: “A atividade de campo pode ser utilizada para prover ambientes propícios ao ensino de matemática?”. Diante disso, neste artigo é apresentada uma atividade de campo no ensino de matemática com o subsídio das Tecnologias de Informação e Comunicação (TIC) como instrumentos utilizados durante seu desenvolvimento. Tendo como objetivo o de verificar se a atividade de campo pode auxiliar no ensino de razões trigonométricas no triângulo retângulo ao se fazer medidas de alturas de difícil acesso. Para atingir tal objetivo, essa investigação ocorreu com uma turma do 2° ano do ensino médio-técnico do Instituto Federal de Mato Grosso, Campus Confresa. Os parâmetros das atividades foram elaborados conjuntamente com os estudantes, que se dividiram em 3 grupos, realizando as atividades de modo extraclasse e tendo orientações por meio das TIC. Esse estudo mostrou que as atividades de campo podem favorecer o ensino de matemática que habitualmente é realizado dentro da sala de aula, pois os estudantes sentiram-se integrantes do processo e motivados por terem transpassado o ambiente da própria sala de aula. Palavras-chave: Atividades de Campo. Tecnologias de Informação e Comunicação. Ensino de Matemática. Trigonometria.