bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indicators of candidates for gentrification: a spatial framework
Authors: Bengtsson Ingemar , Kopsch Fredrik 
Published: April 2019

Purpose
The purpose of this paper is to establish measurable factors that can be used as early indicators of which neighborhoods are most likely to undergo a process of gentrification in a reasonably near future.

Design/methodology/approach
Using 1990 data on key demographic variables for 128 neighborhoods in Stockholm, Sweden a model that allows both for testing of spatial clustering and for spatial spillovers between neighborhoods is estimated. It is hypothesized not only that gentrification depends on inter-neighborhood characteristics but also that gentrified neighborhoods will cluster and preferably be located in proximity to existing high income neighborhoods.

Findings
The findings confirm the stated hypotheses. Among the results, it is shown that neighborhoods that gentrified between 1990 and 2012 were more likely to have been poor in 1990 and located closer to the CBD, they were also more likely to be close to neighborhoods with lower proportions of low income residents. It is also found that gentrified neighborhoods tend to cluster over space.

Originality/value
Much of the previous literature on gentrification has concerned the actual driving forces behind gentrifying neighborhoods. This paper is more concerned with indicators that can be used to spot neighborhoods that are likely to undergo a gentrification process in the future. Such information can be valuable for real estate developers in the private sector, as it may lead to more successful investments. It may also be useful for city developers at the municipal organization.
A new model for Islamic cooperative mortgage of housing finance
Authors: Nasir Aslina , Abdullah Lazim 
Published: April 2019

Purpose
This study aims to propose a new model of Islamic cooperative mortgage of housing finance (ICOM) to provide a lower monthly initial amount with a longer tenure for the low- and middle-income members. This model is developed to ease the burden on borrowers concerning the high initial down payment (ID).

Design/methodology/approach
The ICOM model is a no-interest mortgage and is developed based on the cooperative home mortgage model by Ebrahim (2009). The model is verified using numerical examples to ensure its feasibility to produce lower monthly initial amounts and compared to the cooperative home mortgage.

Findings
From the numerical example, the ICOM model shows a lower monthly initial amount with a longer tenure compared to the cooperative home mortgage. The monthly payment is also lower than the cooperative home mortgage.

Research limitations/implications
The authors compare their model with Ebrahim’s (2009) cooperative home mortgage because of a constraint of limited previous studies on housing finance. Therefore, this model is developed by considering the unaffordability of the initial down payment among low-income borrowers. As this model introduces a lower monthly initial amount, the authors expect it can reduce the unaffordability problem of high initial down payment.

Practical implications
The authors also expect that a lower monthly initial amount with a longer tenure can ease the burden among the low-income borrowers by reducing their consumption on housing.

Originality/value
This paper provides a non-interest Islamic cooperative mortgage and lower monthly initial amount with a longer tenure for the low- and middle-income borrowers.
Going the distance: a lesson study on deriving the distance formula
Authors: Chua Von Christopher Gulpric 
Published: April 2019

Purpose
The purpose of this paper is to determine the challenges that Filipino Mathematics teachers face while developing students’ ability to derive the distance formula; allow teachers to collaboratively formulate a lesson designed to address the challenges they have identified from their own practice; and determine how successful the lesson was and how it can be improved so that other teachers dealing with similar difficulties may be able to implement it. The teacher-participants employed Lesson Study (LS) as an approach to improving pedagogical practice. Data were based on the pre- and post-lesson discussions and individual reflection papers of the teacher participants.

Design/methodology/approach
An action research methodology through LS approach was employed by the teacher participants. Data were based on the pre- and post-lesson discussions and individual reflection papers of the teacher participants.

Findings
Based on the post-lesson discussion, the teachers agreed that the process of creating a lesson that seeks to develop the students’ ability to derive formulas are crucial to building understanding of the underlying mathematical concept. Also, teachers’ participation in LS was found to have been insightful as it developed in them a greater appreciation towards establishing a professional learning community that is directed towards examining problems that concerns majority of the teachers involved.

Originality/value
Research in Philippine education has recently seen the increasing interest in LS as a potent pedagogical practice. Nonetheless, papers that report on LS practice in the local context remains to be lacking. This study contributes to the development of this research area and raises the need for Filipino Mathematics teachers to engage in both LS and action research to generate knowledge from their experiences.
SEC charges “ICO Superstore” as unregistered broker-dealer
Authors: Sikora Jr. John J. , Wink Stephen P. , Yatter Douglas K. , Culhaci Naim 
Published: April 2019

Purpose
To analyze the settled order of the US Securities and Exchange Commission (SEC) against TokenLot LLC (TokenLot), which was the SEC’s first action charging a seller of digital tokens as an unregistered broker-dealer.

Design/methodology/approach
Analyzes the SEC’s order within the context of other recent actions by the SEC on cryptocurrencies and digital tokens and discusses future implications of the order in this area.

Findings
The SEC’s order against TokenLot as an unregistered broker-dealer was a logical next step in its enforcement activity in the cryptocurrency and digital token space.The order demonstrates that the SEC expects firms in the cryptocurrency space to use the well-established constructs of federal securities laws to evaluate their business activities to ensure those activities are legally compliant.

Originality/value
Practical guidance from experienced securities and financial services lawyers analyzing recent developments in a nascent area of SEC enforcement.
Successful work cultures: recommendations for leaders in healthcare
Authors: Vazquez Christian E. 
Published: April 2019

Purpose
The purpose of this study is to gather information about work culture characteristics from four successful pediatric heart programs to better understand how they continue to maintain high standards of quality and safety.

Design/methodology/approach
For this qualitative study, data were collected through semi-structured in-depth individual interviews with four physician leaders. Those interviews were transcribed and coded for themes, first individually and then across all four.

Findings
Three themes emerged from the analysis. According to the experts, the three most salient elements for sustaining a successful work culture that is conducive to maintaining high standards of care are: the ‘right’ people, an effective leadership team and efficient systems.

Research limitations/implications
This was a small homogenous sample, which is a limitation of the study. All of the programs were from non-profit teaching hospitals in urban areas. This study has important research implications, as it offers descriptive information useful for guiding a future explanatory study.

Practical implications
Recommendations have been made for leaders in healthcare settings to benchmark against the work being done at these programs that maintain high standards of quality and safety.

Social implications
This information has important social and practical implications as healthcare leaders continue to work on improving quality and safety that affects patients across the country.

Originality/value
This study contributes to the literature by offering perspectives on successful work cultures from a diverse compilation of physician leaders and medical institutions across the USA.
Family involvement, corporate governance and dividends in Turkey
Authors: Sener Pinar , Akben Selcuk Elif 
Published: April 2019

PurposeThe purpose of this paper is to investigate the relationship between dividends and family involvement as well as corporate governance characteristics among Turkish public firms.Design/methodology/approachUsing panel data on Turkish firms listed on the Borsa Istanbul 100 index for 2006–2014, three models are estimated. For the first two models, where the dependent variables are the dividend payout ratio and dividend yield, respectively, tobit regressions are run. The last model, which employs a dividend dummy as the dependent variable, is estimated with logistic regression.FindingsThere is a positive and concave relationship between family ownership and dividends. The existence of a family chairman reduces dividends. There is a positive association between board size and dividends and this relationship is weaker for firms with higher levels of family ownership. Finally, the ratio of independent directors on the board is negatively associated with dividends.Practical implicationsThe findings imply that firms with substantial family ownership and active family participation in management are more likely to send a negative signal to minority shareholders by paying lower dividends. In addition, minority shareholders should pay attention to the board structure of firms in which they invest.Originality/valueThis study is one of the few to analyze the nonlinear relationship between family ownership and dividend payments as well as the role of family management in a developing country. Second, it investigates the role of board characteristics in explaining dividend payment decisions.
The impact of politics and economic policy uncertainty on anomaly-based investment strategies
Authors: Mbanga Cedric , Jones Jeffrey Scott , Hoelscher Seth A. 
Published: April 2019

Purpose
The purpose of this paper is to explore the overlooked relationship between politics and the performance of anomaly-based investment strategies.

Design/methodology/approach
Monthly long-short portfolios are formed based on relative mispricing scores according to the Stambaugh et al. (2012, 2015) relative mispricing measure. Portfolio performance is examined throughout various presidential terms. The design also introduces economic policy uncertainty (EPU) as a possible explanatory variable for portfolio performance.

Findings
The analysis reveals that anomaly-based returns are higher under Republican administrations than they are under Democratic administrations. Moreover, the results show that the impact of EPU on the relationship between the political party affiliation of the president and future anomaly-based returns are driven by the election and post-election years.

Practical implications
The examination of returns on a long-short portfolio may be of particular value to investment companies, such as hedge funds, who regularly employ this type of strategy.

Originality/value
While the impact of presidential terms on raw equity returns has been well examined, the paper is the first to examine the impact of presidential terms on the return of an anomaly-based investment strategy. EPU is also introduced as an important contributing factor.
Investigation of clinical factors associated with longer overall survival in advanced melanoma patients treated with sequential ipilimumab
Authors: Muto Yusuke , Kitano Shigehisa , Tsutsumida Arata , Namikawa Kenjiro , Takahashi Akira , Nakamura Yoshio , Yamanaka Takeharu , Yamamoto Noboru , Yamazaki Naoya 
Published: April 2019

AbstractMelanoma is one of the most serious form of skin cancer. Nowadays, ipilimumab is used for advanced melanoma refractory to first‐line anti‐programmed death 1 (PD‐1) antibodies. Thirty patients (male : female ratio, 18:12; median age, 60.5 years) sequentially treated with ipilimumab after anti‐PD‐1 antibody (nivolumab or pembrolizumab), while 58 (male : female ratio, 27:31; median age, 66.5 years) with anti‐PD‐1 antibody only. The kind of therapy and schedules were as follows: nivolumab, 2 mg/kg at 3‐week intervals or at 3 mg/kg every 2 week; pembrolizumab, 2 mg/kg every 3 weeks; ipilimumab, 3 mg/kg at 3‐week intervals for four doses. The sequential therapy was selected for the patients with disease progression and/or recovered from severe (immune‐related [ir]) adverse events (AE) after PD‐1 blockade monotherapy. We evaluated multiple parameters and analyzed their relevance to overall survival (OS). The best objective response rate was 6.7% in sequential ipilimumab treatment. Median OS was 163 days (range, 16–489). Baseline absolute lymphocyte count (ALC) and performance status (PS) before sequential ipilimumab were associated with OS in univariate analyses. Baseline PS and irAE within 6 weeks after ipilimumab administration showed significant differences on multivariate analysis. Prior to first‐line PD‐1 blockade, these parameters were not associated with OS. The other factors (i.e. age, sex, number of doses, absolute neutrophil counts, neutrophil : lymphocyte ratio, lactate dehydrogenase and C‐reactive protein) were not associated with OS. [Correction added on 17 April 2019, after first online publication: ‘not related to OS' has been amended to ‘not associated with OS’.] Ipilimumab as sequential therapy did not appear to improve OS and was associated with more severe irAE than PD‐1 blockade monotherapy. We need to carefully consider treating patients with poor PS and low ALC.
What kind of ‘a girls’ thing’? Frictions and continuities in the framing and taming of the HPV vaccine in Finland
Authors: Virtanen Mikko J. 
Published: April 2019

AbstractThis article focuses on two different ways of framing and taming the uncertainties of the human papillomavirus (HPV) vaccine in the context of the Finnish welfare state: the bio‐medical rationale of population‐level cancer reduction based on epidemiological assessments, and the meaning formation of Finnish vaccination‐aged girls. Epidemiologists run analyses estimating the cost‐effectiveness and public health benefit of vaccinations, while the adolescent girls face the burdensome choice of whether to undergo vaccination. The processes of framing the complexities and actively taming them are analysed utilising a cultural‐sociological framework. Firstly, the taming work of the epidemiologists is examined by focusing on the creation of the vaccination campaign. The aetiological complexities between some HPV types and cervical cancer are tamed into a clear campaign message of vaccination as a scientifically proven protection against deadly cancer. Secondly, the girls’ own ways of framing the complexities of the HPV vaccine and taming the decision whether to undergo vaccination or not are analysed based on their comments in an Internet discussion forum. Finally, the framings and tamings of both sites are discussed together, and some interesting continuities and disjunctions between the two are revealed.
Greening the poor: the trap of moralization
Authors: Malier Hadrien 
Published: April 2019

AbstractThis article uses ethnographic data to engage a critical reflection on the tension between individual responsibility for the environment and inequality. While research has shown that the majority of sustainable consumers are middle and upper class, educated and white individuals, the study explores how the ethical injunction to ecological sustainability is being introduced to lower‐income neighbourhoods in France. It draws on the observation of a national programme which aims at supporting inhabitants of public housing estates in the process of greening their lifestyle in order to fight climate change and fuel poverty. The paper analyses how environmental responsibilization is specific in that it calls upon a responsibility towards others, towards the common good. Using the Foucauldian concept of ‘subjectivation’, it describes and analyses the moral work implied by such behaviour change programmes. It demonstrates that a negative representation of poor households and a moral framing of the responsibility for the environment lead to a moralization of their lifestyle under the heading of ‘eco‐friendly behaviours’. A paradoxical result of such endeavours is that the social group with the least impactful lifestyle on the environment is the one which is moralized in the most intrusive and resolute manner. The article shows, however, that the tenants manage to resist the normalizing discourse on sustainable living, for reasons which are not anti‐environmentalist. This piece thus provides interesting results for sustainability studies as well as for the sociology of the regulation of underprivileged neighbourhoods.
The risk of intrapartum/neonatal mortality and morbidity following birth at 37 weeks of gestation: a nationwide cohort study
Authors: Eskes M , Ensing S , Groenendaal F , Abu‐Hanna A , Ravelli ACJ 
Published: April 2019

ObjectiveTo assess intrapartum/neonatal mortality and morbidity risk in infants born at 37 weeks of gestation compared with infants born at 39–41 weeks of gestation.DesignNationwide cohort study.SettingThe Netherlands.PopulationA total of 755 198 women delivering at term of a singleton without congenital malformations during 2010–14.MethodsWe used data from the national perinatal registry (PERINED). Analysis was performed with logistic regression and stratification for the way labour started and type of care.Main outcome measuresIntrapartum or neonatal mortality up to 28 days and adverse neonatal outcome (neonatal mortality, 5‐minute Apgar <7, and/or neonatal intensive care unit admission).ResultsAt 37 weeks of gestation intrapartum/neonatal mortality was 1.10‰ compared with 0.59‰ at 39–41 weeks (P < 0.0001). Adjusted odds ratio (aOR) for 37 weeks compared with 39–41 weeks was 1.84 (95% CI) 1.39–2.44). Adverse neonatal outcome at 37 weeks was 21.4‰ compared with 12.04‰ at 39–41 weeks (P < 0.0001) with an aOR 1.63 (95% CI 1.53–1.74). Spontaneous start of labour at 37 weeks of gestation was significantly associated with increased intrapartum/neonatal mortality with an aOR of 2.20 (95% CI 1.56–3.10), in both primary (midwifery‐led) care and specialist care. Neither induction of labour nor planned caesarean section showed increased intrapartum/neonatal mortality risk.ConclusionsBirth at 37 weeks of gestation is independently associated with a higher frequency of clinically relevant adverse perinatal outcomes than birth at 39–41 weeks. In particular, spontaneous start of labour at 37 weeks of gestation doubles the risk for intrapartum/neonatal mortality. Extra fetal monitoring is warranted.Tweetable abstractBirth at 37 weeks of gestation gives markedly higher intrapartum/neonatal mortality risk than at 39–41 weeks, especially with spontaneous start of labour.
A guide to the application of Hill numbers to DNA‐based diversity analyses
Authors: Alberdi Antton , Gilbert M. Thomas P. 
Published: April 2019

AbstractWith the advent of DNA sequencing‐based techniques, the way we detect and measure biodiversity is undergoing a radical shift. There is also an increasing awareness of the need to employ intuitively meaningful diversity measures based on unified statistical frameworks, so that different results can be easily interpreted and compared. This article aimed to serve as a guide to implementing biodiversity assessment using the general statistical framework developed around Hill numbers into the analysis of systems characterized using DNA sequencing‐based techniques (e.g., diet, microbiomes and ecosystem biodiversity). Specifically, we discuss (a) the DNA‐based approaches for defining the types upon which diversity is measured, (b) how to weight the importance of each type, (c) the differences between abundance‐based versus incidence‐based approaches, (d) the implementation of phylogenetic information into diversity measurement, (e) hierarchical diversity partitioning, (f) dissimilarity and overlap measurement and (g) how to deal with zero‐inflated, insufficient and biased data. All steps are reproduced with real data to also provide step‐by‐step bash and R scripts to enable straightforward implementation of the explained procedures.
KCNQ1OT1 promotes autophagy by regulating miR‐200a/FOXO3/ATG7 pathway in cerebral ischemic stroke
Authors: Yu Shijia , Yu Mingjun , He Xin , Wen Lulu , Bu Zhongqi , Feng Juan 
Published: April 2019

AbstractDysregulation of long noncoding RNAs (lncRNAs) is associated with abnormal development and pathophysiology in the brain. Increasing evidence has indicated that ischemic stroke is becoming the most common cerebral disease in aging populations. The treatment of ischemic stroke is challenging, due in part to ischemia and reperfusion (I/R) injury. In this study, we revealed that potassium voltage‐gated channel subfamily Q member 1 opposite strand 1 (KCNQ1OT1) was significantly upregulated in ischemic stroke. Knockdown of KCNQ1OT1 remarkably reduced the infarct volume and neurological impairments in transient middle cerebral artery occlusion (tMCAO) mice. Mechanistically, KCNQ1OT1 acted as a competing endogenous RNA of miR‐200a to regulate downstream forkhead box O3 (FOXO3) expression, which is a transcriptional regulator of ATG7. Knockdown of KCNQ1OT1 might inhibit I/R‐induced autophagy and increase cell viability via the miR‐200a/FOXO3/ATG7 pathway. This finding offers a potential novel strategy for ischemic stroke therapy.
Impaired frontostriatal functional connectivity among chronic opioid using pain patients is associated with dysregulated affect
Authors: McConnell Patrick A. , Garland Eric L. , Zubieta Jon‐Kar , Newman‐Norlund Roger , Powers Shannon , Froeliger Brett 
Published: April 2019

AbstractPreclinical studies have shown effects of chronic exposure to addictive drugs on glutamatergic‐mediated neuroplasticity in frontostriatal circuitry. These initial findings have been paralleled by human functional magnetic resonance imaging (fMRI) research demonstrating weaker frontostriatal resting‐state functional connectivity (rsFC) among individuals with psychostimulant use disorders. However, there is a dearth of human imaging literature describing associations between long‐term prescription opioid use, frontostriatal rsFC, and brain morphology among chronic pain patients. We hypothesized that prescription opioid users with chronic pain, as compared with healthy control subjects, would evidence weaker frontostriatal rsFC coupled with less frontostriatal gray matter volume (GMV). Further, those opioid use‐related deficits in frontostriatal circuitry would be associated with negative affect and drug misuse. Prescription opioid users with chronic pain (n = 31) and drug‐free healthy controls (n = 30) underwent a high‐resolution anatomical and an eyes‐closed resting‐state functional scan. The opioid group, relative to controls, exhibited weaker frontostriatal rsFC, and less frontostriatal GMV in both L.NAc and L.vmPFC. Frontostriatal rsFC partially mediated group differences in negative affect. Within opioid users, L.NAc GMV predicted opioid misuse severity. The current study revealed that prescription opioid use in the context of chronic pain is associated with functional and structural abnormalities in frontostriatal circuitry. These results suggest that opioid use‐related abnormalities in frontostriatal circuitry may undergird disturbances in affect that may contribute to the ongoing maintenance of opioid use and misuse. These findings warrant further examination of interventions to treat opioid pathophysiology in frontostriatal circuitry over the course of treatment.