bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phaeochromocytomas/paragangliomas and adverse clinical outcomes in patients with Neurofibromatosis type 1
Authors: Al-Sharefi A , Perros P , James R A 
Published: August 2018

Introduction
Phaeochromocytomas/paragangliomas (PHAEO/PG) are linked to hereditary syndromes including Neurofibromatosis type 1 (NF-1). Current guidelines do not recommend biochemical screening for PHAEO/PG in asymptomatic or normotensive patients with NF-1. This strategy may miss preventable morbidities in those patients who ultimately present with symptomatic PHAEO/PG. Our aim was to review the literature and extract data on mode of presentation and the incidence of reported adverse outcomes.

Methods
PubMed and EMBASE literature search using the keywords ‘Phaeochromocytoma’, ‘Paraganglioma’ and ‘Neurofibromatosis’ was performed looking for reported cases from 2000 to 2018.

Results
Seventy-three reports of NF-1 patients with PHAEO/PG were found. Patients were predominately women (n = 40) with a median age of 46 years (range 16–82). PHAEO/PG was found incidentally in most patients, 36/73 did not present with typical symptoms while 27 patients were normotensive at diagnosis. Thirty-one patients had adverse outcomes including metastases and death.

Conclusion
Given the protean presentation of PHAEO/PG, relying on symptomology and blood pressure status as triggers for screening, is associated with adverse outcomes. Further studies are required to ascertain whether biochemical screening in asymptomatic and normotensive patients with NF-1 can reduce the rate of adverse outcomes.
INFLUENCE OF INFORMATION SYSTEMS ON THE POTENTIAL OF THE ENTERPRISE
Authors: Smirnova E. V. 
Published: August 2018

The urgency of solving the problems of increasing the competitiveness of enterprises through the use of information systems is shown. The term «information system» is interpreted on the basis of Russian, international standards and federal laws of the Russian Federation. The essence and role of information systems in achieving business goals of enterprises is disclosed, the main types of information systems, their purpose and composition are described. The economic efficiency of the use of information systems is grounded.
STRATEGY OF CLINICAL NUTRITION DEVELOPMENT IN AMBULATORY AND POLYCLINIC ENVIRONMENT: PERSPECTIVES OF COOPERATION BETWEEN PUBLIC HEALTH CARE SYSTEM AND PRIVATE BUSINESS
Authors: Zubritsky V. F. , Kozin S. M. , Ikonnikov D. G. , Pilyus E. V. 
Published: August 2018

This research is devoted to problems of organization and financing clinical nutrition system in ambulatory and polyclinic environment. First, an overview of foreign solutions is provided, including such contributors as state healthcare organizations and private investors. Second, an importance and necessity of solid clinical nutrition system existence is proved. Third, channels of public-private partnership model implementation are investigated and evaluated; moreover, the main objectives are set: these are to be solved using the public-private partnership model in order to achieve substantial progress in the clinical nutrition system development.
INFLUENCE OF ELECTRONIC BUSINESS ON DEVELOPMENT OF THE COMPANIES OF THE INDUSTRY OF FASHION
Authors: Lukyanova A. V. 
Published: August 2018

Today practice of creation own online of business is widespread in the USA and Europe while in Russia similar practice only gathers gradually a turn. Nevertheless, in Russia start treating a similar kind of activity more seriously. An objective of this research - to determine expediency of maintaining by the luxury fashionable companies of commercial activity online on the example of the largest foreign players. As a result of research it is defined that purchase online of goods of haute couture – a question ambiguous as many do not find in general need for acquisition of similar things owing to economic prerequisites and personal claims. During research it was revealed that the beginning of active sales of luxury goods, in particular clothes subjects, can negatively influence brand representation for perception of the consumer. The following conclusion concerns the main channel of communications between the buyer and the seller. Despite probable negative effects of sales online, nevertheless, the companies should be reoriented and conduct vigorous marketing activity in a network. Physical shops – an important aspect of maintenance of the status, but it is possible to assume that this services industry is developed quite strongly. Other situation is about online marketiny for фэшн the industries, after all in fact, 10 years ago the companies as Chanel, Dior were categorically against similar shift of values towards digital technologies, today it is inevitable.
A Feasibility Study of Restorative Yoga Versus Vigorous Yoga Intervention for Sedentary Breast and Ovarian Cancer Survivors
Authors: Lapen Kaitlyn , Benusis Lara , Pearson Stephanie , Search Benjamin , Coleton Marci , Li Q. Susan , Sjoberg Daniel , Konner Jason , Mao Jun J. , Deng Gary 
Published: August 2018

Abstract
Yoga has been shown to improve cancer survivors' quality of life, yet regular yoga practice is a challenge for those who are sedentary. We conducted a pilot randomized controlled study to assess feasibility and adherence of two types of yoga intervention among sedentary cancer survivors. Sedentary breast and ovarian cancer survivors were randomized to practice either restorative yoga (minimal physical exertion, Group R) or vigorous yoga (considerable physical exertion, Group V) in three 60-minute supervised sessions a week for 12 weeks, followed by 12 weeks of home practice. Accrual, adherence, and attendance rates were assessed. Of the 226 eligible patients, 175 (77%) declined to participate in the study, citing time commitment and travel as the most common barriers. Forty-two subjects consented to participate in the study. Of the 35 participants who began the intervention (20 in Group R and 15 in Group V), adherence rate (percentage remaining in the study at week 12) was 100% and 87%, respectively. Rate of adequate attendance (more than 66% of the scheduled supervised sessions) was 85% and 73%, respectively. Rate of completion of the home practice period was 85% and 77%, respectively. In this study, sedentary cancer survivors were able to adhere to a long-term, regular yoga regimen. The rate of adequate attendance was higher for restorative yoga. Future studies for sedentary patients should focus on reducing time commitment and travel requirements to improve recruitment, and on using restorative yoga as a more feasible intervention for this population.
O USO METODOLÓGICO DA MÚSICA PARA A OTIMIZAÇÃO NO ENSINO DE LITERATURA
Authors: De Sousa Elizeu Arruda , Brito Juliana da Conceição 
Published: August 2018

O presente artigo intitula-se “O uso metodológico da música para otimização no ensino de Literatura” e tem por objetivo demonstrar a relevância das ações didáticas criativas com a utilização da música para despertar o interesse dos alunos pela disciplina em menção. Pode-se averiguar que o ensino de Literatura, muitas vezes, está desprovido de criatividade metodológica, não permitindo aos discentes ter uma aproximação consistente com a disciplina. É perceptível, no contexto escolar, que, com certa frequência, o trabalho didático com o texto literário fica limitado a certos procedimentos metodológicos que não envolvem os alunos de maneira que possam despertar interesse dos discentes; vários são os fatores que contribuem para que o ensino de literatura não seja desenvolvido de maneira satisfatória, dentre os quais se destaca a pouca prática de leitura entre os alunos e a ausência de metodologias mais instigantes e estimuladoras da aprendizagem discente. O artigo pauta-se uma pesquisa bibliográfica, tendo-se respaldo em trabalhos de estudiosos, entre eles podem-se destacar: Bréscia (2003), Silva (2003), Oliveira; Soares (2005), Cosson (2004), Cereja (2005), dentre outros. Tem-se, ainda, o relato, na parte final desse artigo, do desenvolvimento das ações metodológicas com o uso da música em uma turma pertencente a uma escola da rede pública estadual da cidade de Caxias-Maranhão. PALAVRAS-CHAVE: Música. Literatura. Metodologias.
CRENÇAS E ATITUDES LINGUÍSTICAS: O QUE DIZEM OS MARANHENSES SOBRE SUA FALA
Authors: Miranda Antonio Luiz Alencar , Vieira dos Santos Valdinete , Carvalho da Silva Frankilson 
Published: August 2018

O estudo das crenças e atitudes vem se destacando no cenário da Sociolinguística Variacionista, pois, por meio desses dados, podemos esclarecer fenômenos não explicáveis pelo contexto linguístico e social. Dentro desse conjunto, outro fator é de suma importância para a análise de fatos voltados para a linguagem: as atitudes valorativas que cada falante assume frente à sua fala. Por essas razões, optamos como objeto de estudo as crenças e atitudes dos falantes da cidade de Caxias-MA, com os objetivos de pesquisar as crenças e atitudes linguísticas dos falantes caxienses em relação a sua língua. O corpus do trabalho constitui-se de registros orais coletados, por meio de entrevistas face a face, e que faz parte do projeto Atitudes Linguísticas dos falantes do Maranhão (ALFMA), com os informantes estratificados por sexo, faixa etária e nível de escolaridade. Ao todo, analisamos 36 entrevistas, tendo como base teórica, entre outros, os trabalhos Labov (2008), Weinreich, Labov e Herzog (2006), Tarallo (1990), Lambert & Lambert (1975), Lambert (1967), Bagno (1999), Miranda (2014). Os resultados da pesquisa apontam para crenças e atitudes positivas em favor da língua falada por maranhenses e indicam os homens, a menor faixa etária e a menor escolaridade como as que avaliam que os maranhenses falam o melhor português. PALAVRAS-CHAVE: Sociolinguística. Crenças e atitudes. Variação. Mudança.
Arqueologia experimental guarani na formação de professores(as) em ciências humanas: uma experiência na cidade missioneira de São Borja
Authors: Pouey Vidal Viviane 
Published: August 2018

o presente artigo aborda as atividades de ensino-aprendizagem da História Indígena Guarani realizadas com os Professores(as) em Formação em Ciências Humanas na UNIPAMPA, Campus São Borja a partir da Arqueologia Experimental. O objetivo central das atividades realizadas foi colaborar com a formação inicial dos professores(as), que irão atuar na educação básica, bem como difundir a importância da arqueologia nos espaços escolares. Nessa perspectiva, aliou-se a teoria das componentes curriculares: Metodologia para o Ensino em Ciências Humanas; Educação e Identidade na Fronteira Oeste; Educação e Patrimônio com as práticas de ensino e confecção de réplicas da cerâmica Guarani. As oficinas interdisciplinares possibilitaram aos licenciandos(as) um maior contato com a história indígena, sua arte e cultura, bem como permitiram a criação de espaços pedagógicos para a produção de recursos didáticos.
DROGAS E ALIMENTOS (IN) SAUDÁVEIS NO CONTEXTO DA GOVERNAMENTALIDADE NEOLIBERAL
Authors: Azevedo Elaine , Rosa Pablo Ornelas , Siqueira Marluce Mechelli de 
Published: August 2018

Este estudo conceitual propõe uma problematização sobre os conceitos de drogas e alimentos, sem a pretensão de esgotar a temática ou definir uma relação, cujas fronteiras revelam-se porosas e flexíveis. Apresentamos um panorama de fatos que demonstram a variedade de atores e elementos discursivos envolvidos na construção social desses conceitos, bem como desejamos estimular estudos futuros que poderão garantir a consolidação de uma abordagem epistemológica sobre essa relação ainda vaga. Nossa análise gera questionamentos que apontam a impossibilidade de governamentalizar uma simplificação dos conceitos e apontam associações arbitrariamente imprecisas, construídas sob o aval do viés positivista-biologicista da medicina e da ciência moderna - supostamente isento de interesses políticos e econômicos - e da governamentalidade neoliberal tratada pela analítica foucaultiana como um conjunto de instituições, procedimentos, análises, reflexões, cálculos e táticas que possibilitaram um tipo de exercício de poder que tem a população como seu alvo; a economia política como principal forma de saber; e o dispositivo de segurança como seu instrumento técnico mais elementar. Nesse sentido, o artigo apresentado propõe ponderações acerca da imprecisão na atribuição da condição de drogas e alimentos, tendo em vista que ambos foram instrumentalizados historicamente de maneira indefinida, variando de acordo com as conjunturas e interesses que atravessam esses condicionamentos conceituais que ora qualificam certo produto - em decorrência de estratégias qualificadores - como alimento, ora o desqualificam tratando-o como drogas – justamente por seus supostos prejuízos causado à saúde humana e/ou ambiental.
Sustainable Adoption of Digital Health Innovations: Perspectives From a Stakeholder Workshop (Preprint)
Authors: Van Velthoven Michelle Helena , Cordon Carlos 
Published: August 2018

BACKGROUND

There are various complex reasons that influence sustainable adoption of innovations in health care systems. Low adoption can be caused by a lack of support from one or more stakeholders because their needs and expectations are not always considered or aligned.

OBJECTIVE

This study aimed to identify stakeholders’ perceptions of barriers and facilitators toward the sustainable adoption of digital health innovations.

METHODS

A stakeholder workshop was attended by 12 participants with a range of backgrounds on August 25, 2017, including people representing the views from patients, carers, local hospitals, pharmacy retailers, health insurers, health services researchers, engineers, and technology and pharmaceutical companies in Switzerland. On the basis of adoption of innovation frameworks, we asked participants to interview each other about 3 factors influencing the adoption of digitally delivered health interventions: (1) Facilitators and barriers in the external system, (2) Needs and expectations of stakeholders, and (3) Safety, quality, and usability of innovations. The worksheets and videos generated from the workshop were qualitatively analyzed and summarized.

RESULTS

Facilitators for adoption mentioned were high levels of income and education, and digital health is a high priority to stakeholders. Main common interests of different stakeholders were patient satisfaction and job protection. Health care spending was a misaligned interest: although some stakeholders were keen on spending more to obtain or provide the highest quality of care, others were focused on reducing health care spending to provide cost-effective services. Switzerland’s diversity and complexity, in terms of its organization with 26 cantons (administrative divisions), were barriers as these made it harder to ensure interoperability of interventions. A culture of innovation was considered a push factor, but adoption was inhibited by persistent paper-based systems, a fear of change, and unwillingness to share data. The sustainability of interventions can be promoted by making them patient-centered, meaning that patients should be involved throughout their development.

CONCLUSIONS

Promoting sustainable adoption of digital health remains challenging despite various push factors being in place. Barriers related to fragmentation, patient-centeredness, data security, privacy, trust, and job security need to be addressed. A strength is that people from a wide range of backgrounds attended the workshop. A limitation is that the findings are focused on the macro level. In-depth case studies of specific issues need to be conducted in different settings.
Control societies and the crisis of science journalism
Authors: Castelfranchi Yuri 
Published: August 2018

In a brief text written in 1990, Gilles Deleuze took his friend Michel Foucault’s work as a starting point and spoke of new forces at work in society. The great systems masterfully described by Foucault as being related to “discipline” (family, factory, psychiatric hospital, prison, school), were all going through a crisis. On the other hand, the reforms advocated by ministers throughout the world (labour, welfare, education and health reforms) were nothing but ways to protract their anguish. Deleuze named “control society” the emerging configuration.
As requested: brief, frank, and informal
Authors: De Marchi Bruna 
Published: August 2018

Scientific journalism ought to pay attention not only to the “products” of science, but also to the ways in which it operates in any given historical and political context. A critical analysis of the presently dominant rhetoric of innovation and unlimited growth is necessary to shed light on the relationship between science and democracy. Equally profitable would be a thorough investigation of past and present controversies on the role of scientists in decision-making.
Community and research
Authors: Polino Carmelo 
Published: August 2018

JCOM is eleven years old, and this is certainly a reason to celebrate. The journal has been a tribune where we could observe how geographical and institutional frontiers of science communication (SC) have been expanded. As open access publication, JCOM has played a key important role to diffuse and make visible the research results for all. This is relevant for many institutions and researchers in Latin America due to the difficulties for paying to access to the papers published by the international scientific journals. The journal has made a relevant contribution to consolidation of the field of SC. Thinking on the future, JCOM may stimulate a global debate on theoretical perspectives about SC, and devote special issues to describe different regional contexts (India and East Asia; Latin America; Africa; or East Europe. The journal also may promote papers, special issues or specific discussions on SC and social theory.
Estudio descriptivo del accidente ofídico, Casanare-Colombia, 2012-2014
Authors: Manosalva-Sánchez Carolina , Zuleta-Dueñas Liliana Patricia , Castañeda-Porras Oneida 
Published: August 2018

Introducción: Entre las lesiones de causa externa, el accidente ofídico es de notificación obligatoria en Colombia. En el departamento de Casanare, la susceptibilidad de sufrir una mordedura de serpiente aumenta dadas sus características geográficas, climáticas, socioculturales y demográficas que favorecen el incremento de morbilidad y mortalidad. Objetivo: Describir la ocurrencia del evento en Casanare entre 2012-2014, con el propósito de fortalecer las acciones de promoción y prevención. Metodología: Estudio descriptivo transversal a partir de registros de la notificación del evento al Sistema de Vigilancia en Salud Pública durante el período a estudio; la información se almacenó en el programa Excel de Microsoft Office®, y se realizó un análisis descriptivo de las variables tiempo, lugar y persona en el programa estadístico Epi-Info 7.1.5®. Resultados: Se registraron 485 casos: en 2012 (175 casos; 36.1%), 2013 (168 casos; 34.6%), 2014 (142 casos; 29.3%); de los cuales 315 fueron en hombres (64.9%), 417 casos del área rural (85.9%), con una edad promedio de 32.4 ± 19.9. En relación a la pertenencia étnica se presentaron 49 casos (10.1%), de los cuales el 83.7% fue en indígenas (41/49). Las actividades más frecuentes al momento de la agresión fueron caminatas por senderos abiertos o labores de agricultura 280 casos (57.7%); realizar trabajos agropecuarios, forestales o pesqueros 124 casos (25.6%). La localización anatómica de la mordedura en orden de frecuencia fue: Miembros inferiores 351 casos (72.4%) y superiores 113 casos (23.3%). Según la atención inicial: Inmovilización de miembro 71 casos (14.7%); sometidos a prácticas no médicas 181 casos (37.3%), y el 54.7% (99/181) se había realizado rezos. La Tasa de incidencia fue de 47.1/100,000 habitantes y de letalidad 0.2% (1/485). Conclusiones: La tasa de incidencia evidenciada superó la del país de 9.2/100,000 habitantes. Afectó a hombres en edad productiva, dependientes del trabajo agrícola; y la atención inicial fue inadecuada en la mayoría de casos, persistiendo el uso de prácticas no médicas. Todas las lesiones son prevenibles, por tanto, las medidas preventivas deben constituirse en la principal herramienta para reducir la incidencia del evento. [Manosalva-Sánchez C, Zuleta-Dueñas LP, Castañeda-Porras O. Estudio descriptivo del accidente ofídico, Casanare-Colombia, 2012-2014. MedUNAB 2017-2018; 20(3): 338-348].
Sex Ratio at Birth: Where Did Our Female Fetus Go?
Authors: Gurung T K , Gurung R T , Shrestha R , Shrestha R 
Published: August 2018

Objectives: The aim of the study was to determine the ratio of male to female gender at birth and compare the sex ratio between primipara and multipara women.Methods: This is a cross sectional retrospective study done using the data available from the medical records of the patients who were admitted in the labor room of Gandaki Medical College Teaching Hospital from July 2016 to June 2017 (Shrawan 2073 to Asad 2074).Results: In one year period, a total of 1625 women were admitted for delivery. There were 845 male and 780 female babies delivered to those women. The sex ratio calculated was 108 male births for every 100 females. When comparing the sex ratios at birth for primipara, multipara with previous abortions and fetal death and mulipara with no history of abortions and fetal death, the sex ratio was 81.75, 125.89 and 120.16 respectively.Conclusions: Overall there were more male births than female. But in primiparous women more female babies were born unlike in multipara. There is definitely a need of in depth study to identify the cause for the skewed value. The society needs to acknowledge that high sex ratios at birth will adversely affect the fertility patterns causing the imbalance in the overall development of community. J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 1-4
Assessment of Adenosine Deaminase Level and the Utility of Polymerase Chain Reaction in Diagnosis of Tuberculous Pleural Effusion
Authors: Nagila A , Khanal S , Dhakal N , Bhatta M , Tamrakar B K 
Published: August 2018

Background: Extrapulmonary tuberculosis is one of the major causes of exudative pleural effusion. The paucibacillary nature of effusion suggests the need of markers and methodologies for accurate diagnosis and prognosis of tuberculosis as well as to differentiate it from other non-tubercular causes of pleural effusion.Objectives: This study was focused to evaluate the utility of polymerase chain reaction (PCR) in detection of tuberculosis antigen and to assess the level of Adenosine Deaminase (ADA) in tubercular pleural effusion (TPE) and contrast it with other causes.Methods: This is a cross-sectional study where 100 samples of pleural effusion suspected to be tuberculosis were analyzed by PCR for the detection of IS6110 segment of DNA. The level of ADA was then determined and compared in both PCR positive and negative samples. The cut-off value of ADA was >40 U/L for TPE. Student t test was applied to compare the means with statistical significance set at p<0.05.Results: Out of 100 samples analyzed, 45% were positive for TPE and remaining 55% were non-tuberculosis pleural effusion as detected by PCR. The level of ADA was above cut-off (>40 U/L) in 43% TPE samples whereas all the non-tuberculosis effusion had ADA <40 U/L (p<0.001).Conclusion: The ADA level was significantly higher in TPE than in non-tuberculosis cases, and PCR was able to detect suspected cases of tuberculosis effusion in almost half of the cases. This finding suggests the diagnostic utility of combined use of ADA and PCR in diagnosis of TPE. J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 5-9