bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global Democracy in Decline?
Authors: Heldt Eugenia C. , Schmidtke Henning 
Published: June 2019

Abstract
Over the past decade, rising authoritarian regimes have begun to challenge the liberal international order. This challenge is particularly pronounced in the field of multilateral development finance, where China and its coalition partners from Brazil, Russia, India, and South Africa have created two new multilateral development banks. This article argues that China and its partners have used the New Development Bank and the Asian Infrastructure Investment Bank to increase their power and to restrict democratic control mechanisms. By comparing formal mechanisms of democratic control in both organizations to the World Bank, this article shows that civil society access, transparency, and accountability are lower at the AIIB and NDB than they are at the World Bank.
Power in Global Nutrition Governance
Authors: Lie Ann Louise 
Published: June 2019

Abstract
Global public-private partnerships for health and nutrition have proliferated since the 1990s—a trend raising important questions about authority and legitimacy in global governance. Yet within the fields of international relations and public health, there has been only limited empirical research into the global politics and power dynamics behind such partnerships. This article explores how and why the Scaling Up Nutrition partnership was established. Drawing on interviews, observations, and document analysis, it demonstrates how public and private actors exercise combinations of instrumental, structural, and discursive power to normalize and institutionalize their interests and values at the global level. The study highlights as such the complexities behind the increased privatization of global nutrition governance and the importance of power analysis to uncover the normative contestations and asymmetries of power behind global partnership creation.
A new species of the genus Nemoura (Plecoptera: Nemouridae) from Xinjiang, China
Authors: WANG ZHI-JIE , DU YU-ZHOU 
Published: June 2019

The genus Nemoura Latreille is distributed widely in the Holarctic and Oriental regions (Baumann 1975, Aubert 1967, Zwick & Sivec 1980). A total of 31 species from China have been described by Klapálek (1907, 1912), Okamoto (1922), Chu (1928), Uéno (1941), Wu (1938, 1949, 1962, 1973), Shimizu (1997), Sicec (1981), Zhu & Yang (2003), Wang & Du (2006), Li & Yang (2006, 2007), and Du et al. (2008). Currently, only one species of nemourid, Amphinemura tricintusidens, Wang & Zhu, 2007 is known from Xinjiang province, China (Wang et al. 2007). A second species from Xinjiang, Nemoura bidentata, is described as new to science in this paper. Types of the new species are placed in the Insect Collection of Yangzhou University and are stored in 75% ethanol. Morphological terminology is that of Baumann (1975).
Is Summer African Dust Arriving Earlier to Barbados? The Updated Long-Term In Situ Dust Mass Concentration Time Series from Ragged Point, Barbados, and Miami, Florida
Authors: Zuidema Paquita , Alvarez Claudia , Kramer Samantha J. , Custals Lillian , Izaguirre Miguel , Sealy Peter , Prospero Joseph M. , Blades Edmund 
Published: June 2019

AbstractSurface dust mass concentrations, extracted from filters collected at Miami, Florida, and Ragged Point, Barbados, since 1974 and 1973, respectively, provide a rare, unusual, and important metric of the intercontinental transport of North African dust. The daily-resolved time series, updated through December 2018 for Miami and through December 2015 along with May–September 2016 and January–March and June–August 2017 for Barbados, indicate summer-mean dust mass concentrations have mostly decreased this decade at Miami, but not at Barbados, where instead the events containing the highest dust mass concentration events may be shifting to earlier in the year.
Investigating the Transition from Elevated Multicellular Convection to Surface-Based Supercells during the Tornado Outbreak of 24 August 2016 Using a WRF Model Simulation
Authors: Gray Kevin , Frame Jeffrey 
Published: June 2019

Abstract
On 24 August 2016, a tornado outbreak impacted Indiana, Ohio, and Ontario with 26 confirmed tornadoes. Elevated multicellular convection developed into surface-based supercells that produced several tornadoes, particularly near a differential heating boundary. This convective mode transition is of particular interest owing to its relatively rare occurrence. A WRF Model simulation accurately captures the environment and storm evolution during this outbreak. Trajectory analyses indicate that the multicellular updrafts were initially elevated. Since nearly all of the vertical wind shear was confined to the lowest 1 km, significant rotation did not develop via tilting of horizontal vorticity until the storms began ingesting near-surface air. Near-surface vertical wind shear decreased outside of cloud cover owing to vertical mixing, while it was preserved under the anvil, allowing for large values of 0–1-km storm-relative helicity to persist north of a differential heating boundary. Analysis of the perturbation pressure field from the WRF Model output indicates that the development of relatively large nonlinear vertical perturbation pressure gradients coincided with when near-surface air began to enter the updrafts, resulting in upward accelerations in the lowest 2 km, below the level of maximum rotation. In strengthening updrafts, upward-directed buoyancy perturbation pressure accelerations may have offset the downward-directed nonlinear perturbation pressure accelerations above the level of maximum rotation, allowing the updrafts to intensify further.
Sizing of medical below-knee compression stockings in an Indian population: A major risk factor for non-compliance
Authors: Jindal Ravul , Uhl Jean-Francois , Benigni JP 
Published: June 2019

Background The compliance to compression stockings in India is poor. One of the reasons is related to the inadequacy of sizing tables of compression stockings sold in India by western companies. Methods In 922 Indian patients, three circumference measurements of leg were taken in a standing position at different levels: Instep (level Y), Ankle (level B) and largest part of the calf (level C). We compared these measurements with the standard sizing tables according to the recommendations of the manufacturers’ sizing tables. The statistical analysis method: mean comparison of the circumferences was tested with the Wilcoxon test. Result The measurements found do not allow a satisfactory adaptation of compression stockings marketed in India by Medi®, Sigvaris® and Jobst®. The risk of threading difficulties is 15% with Medi® and Sigvaris® compression stockings. The risk of slippage is 61% for Sigvaris® and 48% for Medi®. With the Jobst® sizing table, no knitting makes it possible to reach a pressure at point C equal to at least 50% of the pressure of point B. Conclusion These data underline the need to adapt the measurements of compression stockings to the morphologies of patients' lower limbs in India, to improve compliance.
Which outcome domains are important in palliative care and when? An international expert consensus workshop, using the nominal group technique
Authors: de Wolf-Linder Susanne , Dawkins Marsha , Wicks Francesca , Pask Sophie , Eagar Kathy , Evans Catherine J , Higginson Irene J , Murtagh Fliss E M 
Published: June 2019

Background: When capturing patient-level outcomes in palliative care, it is essential to identify which outcome domains are most important and focus efforts to capture these, in order to improve quality of care and minimise collection burden. Aim: To determine which domains of palliative care are most important for measurement of outcomes, and the optimal time period over which these should be measured. Design: An international expert consensus workshop using nominal group technique. Data were analysed descriptively, and weighted according to ranking (1–5, lowest to highest priority) of domains. Participants’ rationales for their choices were analysed thematically. Setting/participants: In all, 33 clinicians and researchers working globally in palliative care outcome measurement participated. Two groups (n = 16; n = 17) answered one question each (either on domains or optimal timing). This workshop was conducted at the 9th World Research Congress of the European Association for Palliative Care in 2016. Results: Participants’ years of experience in palliative care and in outcome measurement ranged from 10.9 to 14.7 years and 5.8 to 6.4 years, respectively. The mean scores (weighted by rank) for the top-ranked domains were ‘overall wellbeing/quality of life’ (2.75), ‘pain’ (2.06), and ‘information needs/preferences’ (2.06), respectively. The palliative measure ‘Phase of Illness’ was recommended as the preferred measure of time period over which the domains were measured. Conclusion: The domains of ‘overall wellbeing/quality of life’, ‘pain’, and ‘information needs/preferences’ are recommended for regular measurement, assessed using ‘Phase of Illness’. International adoption of these recommendations will help standardise approaches to improving the quality of palliative care.
A brief, patient- and proxy-reported outcome measure in advanced illness: Validity, reliability and responsiveness of the Integrated Palliative care Outcome Scale (IPOS)
Authors: Murtagh Fliss EM , Ramsenthaler Christina , Firth Alice , Groeneveld Esther I , Lovell Natasha , Simon Steffen T , Denzel Johannes , Guo Ping , Bernhardt Florian , Schildmann Eva , van Oorschot Birgitt , Hodiamont Farina , Streitwieser Sabine , Higginson Irene J , Bausewein Claudia 
Published: June 2019

Background: Few measures capture the complex symptoms and concerns of those receiving palliative care. Aim: To validate the Integrated Palliative care Outcome Scale, a measure underpinned by extensive psychometric development, by evaluating its validity, reliability and responsiveness to change. Design: Concurrent, cross-cultural validation study of the Integrated Palliative care Outcome Scale – both (1) patient self-report and (2) staff proxy-report versions. We tested construct validity (factor analysis, known-group comparisons, and correlational analysis), reliability (internal consistency, agreement, and test–retest reliability), and responsiveness (through longitudinal evaluation of change). Setting/participants: In all, 376 adults receiving palliative care, and 161 clinicians, from a range of settings in the United Kingdom and Germany Results: We confirm a three-factor structure (Physical Symptoms, Emotional Symptoms and Communication/Practical Issues). Integrated Palliative care Outcome Scale shows strong ability to distinguish between clinically relevant groups; total Integrated Palliative care Outcome Scale and Integrated Palliative care Outcome Scale subscale scores were higher – reflecting more problems – in those patients with ‘unstable’ or ‘deteriorating’ versus ‘stable’ Phase of Illness (F = 15.1, p < 0.001). Good convergent and discriminant validity to hypothesised items and subscales of the Edmonton Symptom Assessment System and Functional Assessment of Cancer Therapy–General is demonstrated. The Integrated Palliative care Outcome Scale shows good internal consistency (α = 0.77) and acceptable to good test–retest reliability (60% of items kw > 0.60). Longitudinal validity in form of responsiveness to change is good. Conclusion: The Integrated Palliative care Outcome Scale is a valid and reliable outcome measure, both in patient self-report and staff proxy-report versions. It can assess and monitor symptoms and concerns in advanced illness, determine the impact of healthcare interventions, and demonstrate quality of care. This represents a major step forward internationally for palliative care outcome measurement.
Effect of microRNA-29b on proliferation, migration, and invasion of endometrial cancer cells
Authors: Kong Jian , He Xiuting , Wang Yan , Li Jie 
Published: June 2019

Objective Aberrant expression of microRNAs is a key regulator of tumorigenesis and progression in endometrial cancer. We assessed the effect of microRNA-29b (miR-29b) on proliferation, chemosensitivity, migration, and invasion of endometrial cancer cells. Methods The proliferation of endometrial cancer cells was examined by water-soluble tetrazolium (WST)-1 assay. The effects of miR-29b on migration and invasion were evaluated by transwell migration and Matrigel invasion assays. Western blotting was used to assess protein expression levels after altered expression of miR-29b. The effect of miR-29b on cisplatin-induced apoptosis was examined by Caspase-Glo 3/7 assay. Results miR-29b inhibited proliferation and decreased migration and invasion of endometrial cancer cells. It also enhanced the sensitivity of endometrial cancer cells to cisplatin and increased cisplatin-induced apoptosis by regulating expression of BAX and Bcl-2. Moreover, miR-29b changed the expression level of phosphatase and tensin homolog (PTEN) and p-AKT by directly binding to the 3′ untranslated region of PTEN. Conclusion miR-29b played important roles in proliferation and progression in endometrial cancer cells by direct regulation of PTEN. It might be used as a biomarker to predict chemotherapy response and prognosis in endometrial cancer.
Effects of Luo Han Guo on throat complications associated with tracheal intubation: a randomized controlled trial
Authors: Tan Hui-Lian , Liang Yu-Kun , Li Yong-Ming , Qiu Li-Yu , Huang Rui , Guo Li , Yang Xiao-Hua , Lu Hui-Xia , Liang Hong-Mei , Chen Ai-Ping 
Published: June 2019

Objectives Conventional treatment for throat complications after surgery involves the use of hormone therapy, which has variable effects. This study was performed to investigate the effects of oral administration of Luo Han Guo decoction for throat complications after tracheal intubation during general anesthesia for laparoscopic radical hysterectomy. Methods Beginning at 6 h after surgery, patients in the experimental group were administered 30 mL of a Luo Han Guo decoction; the control group received black tea. Patients in both groups were evaluated using a Visual Analogue Scale for the degree of throat soreness at 2, 12, 24, and 48 h after surgery; coughing and expectoration were evaluated at 48 h after surgery. Results This study included 203 patients: 102 in the experimental group and 101 in the control group. Compared with controls, the experimental group had significantly lower evaluation scores at 12, 24, and 48 hours postoperatively. Moreover, at 48 hours postoperatively, coughing and expectoration were significantly reduced in the experimental group, compared with in the control group. Conclusions Administration of a Luo Han Guo decoction can effectively reduce throat pain, hoarseness, throat swelling, cough, and sputum after tracheal intubation during general anesthesia.
Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice cocaine toxicity model: an experimental study
Authors: Yilmaz Atakan , Erdur Bulent , Ozen Mert , Sabirli Ramazan , Turkcuer Ibrahim , Sarohan Ahmet , Seyit Murat 
Published: June 2019

Objective To assess the effectiveness of pre-treatment with aripiprazole and quetiapine to prevent acute cocaine toxicity in a mouse model of cocaine toxicity. Methods This experimental study included three groups ( n = 25 per group) of mice that were intraperitoneally injected with normal saline solution, 10 mg/kg quetiapine or 10 mg/kg aripiprazole 15 min before 105 mg/kg cocaine hydrochloride. When the cocaine administration was completed, researchers blinded to the study groups observed the mice in terms of seizures and death for a further 30 min. Results In the cocaine + quetiapine group, the mean ± SE time to the first seizure was 10.80 ± 2.27 min and seizure activity was detected in 18 mice (72%) by the end of the 30 min. In the cocaine + aripiprazole group, the mean ± SE time to the first seizure was 18.10 ± 1.94 min and seizure activity was detected in 15 mice (60%) by the end of the 30 min. When compared with the control group, there was a significant difference between the cocaine + quetiapine and cocaine + aripiprazole groups in terms of seizure activity. Survival time was increased in the cocaine + aripiprazole group compared with the control and cocaine + quetiapine groups. Conclusion Quetiapine and aripiprazole pre-treatment reduced seizure activity and delayed the onset of seizures compared with the control group.
Intravenous Immunoglobulin as a Therapeutic Option for Mycoplasma pneumoniae Encephalitis
Authors: Daba Mebratu , Kang Peter B. , Sladky John , Bidari Sharatchandra S. , Lawrence Robert M. , Ghosh Suman 
Published: June 2019

Objective: To analyze the outcomes of a cohort of children diagnosed with Mycoplasma pneumoniae encephalitis whose treatment regimens included intravenous immunoglobulin (IVIG). Methods: A retrospective study was performed at a single center between 2011 and 2016 of children diagnosed with Mycoplasma pneumoniae encephalitis whose acute treatment regimen included IVIG. Details of therapeutic interventions and the clinical course were retrieved from medical records via an institutionally approved protocol. The modified Rankin score was used to quantify outcomes. Results: Four children met inclusion criteria, 3 of whom had prodromal symptoms of infection lasting 5 to 7 days before onset of their neurologic symptoms. One patient presented with neurologic symptoms with no clinical prodrome. The initial treatment regimen included systemic corticosteroids, antibiotics, or both. IVIG was administered for a total dose of 2 g/kg divided over 2 to 4 days to all 4 children. All children showed clinical improvement after IVIG. The 3 children with prodromal symptoms showed immediate and dramatic clinical improvement after IVIG therapy. Discussion: The immediate response to immunomodulatory therapy in the patients with prodrome suggests that the neurologic syndrome may be caused at least in part by an autoimmune process. The child who did not respond to IVIG had no prodrome, and also had normal electroencephalographic (EEG) and brain magnetic resonance imaging (MRI) findings. These cases suggest that early administration of IVIG should be considered in patients suspected of having Mycoplasma encephalitis, particularly in those who have had prodromal symptoms.
Visual loss from dermal fillers
Authors: Jolly Rohit , Bhalla Minak , Zakir Rahila , Joshi Naresh 
Published: June 2019

Background: An increasing number of people are undergoing non-surgical aesthetic procedures, especially injections of botulinum toxin and dermal fillers. While toxin injections have lower rates of complications, profound and serious consequences can arise with the use of dermal fillers. Case: A 29-year-old woman presented to the eye casualty department with sudden visual loss, ptosis and ophthalmoplegia after having had non-surgical rhinoplasty in a beauty salon in West London. The filler was administered by a healthcare professional not registered with the General Medical Council (GMC) or similar governing body. Discussion: Despite prompt measures on arrival at our service, the symptoms of visual loss, ptosis and ophthalmoplegia persisted. Attempts from the patient and medical services to report the incident (to trading standards and the police) were to no avail. Conclusion: This case highlights the poor treatment response to filler-related ophthalmic complications. It is also evident that in the United Kingdom, there appears to be poor regulation in the use of these products, a lack of clear guidelines for the management of their complications and finally no recourse for patients to challenge practitioners who lack medical registration and are not held accountable.
Complication Incidences and Treatment Outcomes of Endovascular Aneurysm Repair—A Single-Center Long-Time Follow-Up Study
Authors: Andersen Rosa Marie , Rasmussen Benjamin S. B. , Halekoh Ulrich , Langfeldt Sten , Mafi Hossein Mohit , Graumann Ole 
Published: June 2019

Background: Few long-time follow-up studies describe all complications, treatment outcome of complications, and mortality in relation to endovascular aneurysm repair (EVAR). The purpose of this study was to evaluate the incidence and treatment outcome including mortality of radiological visible complications related to the EVAR procedure at a single center with up to 10 years’ surveillance. Materials and Methods: Patients treated with EVAR from March 2006 to March 2016 at a Danish university hospital, 421 in total, were included. Patient and aneurysm characteristics, follow-up, and secondary intervention data were collected from a national database and medical records. Follow-up computed tomography angiography and plain abdominal X-ray reports were reviewed for complications. Scans and X-rays with suspected complications were evaluated by an interventional radiologist. Results: A total of 172 complications in 147 patients, mainly in the beginning of the follow-up period, were found; 35% had a least one complication. The main part of complications (62%) was type II endoleaks, followed by stent graft stenosis (11%), type I endoleaks (9%), and stent graft occlusion (7%). A total of 66 (38%) complications, observed in 55 patients, were treated with reintervention, of which 77% were treated with endovascular procedures and 23% with surgical treatment, that is, 13% of all studied patients had a complication that required a reintervention. The remaining 2 of the 3 complications were treated conservatively. We found no increased all-cause mortality in connection with having a complication including those requiring reintervention. Conclusion: We presented a 10-year single-center study of EVAR. Many patients treated with EVAR had a radiological visible complication, mainly in the beginning of the follow-up period. Only a smaller fraction required reintervention and having a reintervention-requiring complication was not connected to increased mortality.
Management of Less-Than-Severe Aortic Stenosis During Coronary Bypass: A Systematic Review and Meta-Analysis
Authors: Yanagawa Bobby , An Kevin R. , Ouzounian Maral , Gaudino Mario , Puskas John D. , Asaoka Nozomi , Verma Subodh , Friedrich Jan O. 
Published: June 2019

Objective The management of concomitant mild-to-moderate aortic stenosis (AS) at the time of coronary artery bypass graft (CABG) is controversial. Here we perform a systematic review and meta-analysis of CABG and aortic valve replacement (AVR) versus CABG alone in patients with mild–moderate AS. Methods We searched MEDLINE and EMBASE databases until July 2018 for studies comparing CABG & AVR versus CABG in patients with mild–moderate AS undergoing coronary bypass. Data were extracted by 2 independent investigators. The main outcomes were operative mortality, long-term survival, and reintervention for AS. Results There were 6 unmatched retrospective observational studies with 1,172 patients (median follow-up 4.7 [interquartile range: 4.3 to 5.3] years). Patients undergoing CABG & AVR had less severe coronary artery disease. There were no differences in operative mortality (relative risk [RR]: 1.07; 95% CI, 0.59 to 1.94; P = 0.8). CABG & AVR was associated with greater incidence of stroke, bleeding, renal failure, and mediastinitis. At median follow-up of 5 years, there was no difference in long-term mortality (incidence rate ratio [IRR]:1.44; 95% CI, 0.83 to 2.51; P = 0.19), but CABG & AVR was associated with 73% lower risk of reoperation for AS ( n = 13/485 versus n = 71/702; IRR: 0.27; 95% CI, 0.14 to 0.51; P < 0.001). Conclusions In patients undergoing CABG with mild–moderate AS, combining AVR with CABG was associated with no difference in operative mortality but with increased risk of stroke, bleeding, renal failure, and mediastinitis. Long-term mortality was not different, but a risk of reoperation for AS at 5 years was 73% lower. Given the increasingly wide availability and safety of transcatheter aortic valve replacement (TAVR), one may consider a conservative approach toward concomitant mild–moderate AS.