bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of sedation after intranasal administration of midazolam and midazolam-butorphanol in cockatiels (Nymphicus hollandicus)
Authors: Doss Grayson A. , Fink Dustin M. , Mans Christoph 
Published: November 2018

Abstract
OBJECTIVE To compare sedation in cockatiels (Nymphicus hollandicus) after intranasal administration of midazolam and midazolam-butorphanol.
ANIMALS 9 healthy adult cockatiels.
PROCEDURES A randomized, controlled, blinded, complete crossover study was conducted. Birds were assigned to 3 treatment groups. Midazolam (3 mg/kg), midazolam-butorphanol (3 mg/kg for each drug), or sterile saline (0.9% NaCl) solution (control treatment) was administered intranasally. Sedation quality was assessed at 3 time points by use of eye and body position; response to visual, auditory, and tactile stimulation; and response during manual restraint on the basis of eye position and struggling intensity. To evaluate attenuation of the manual restraint–induced stress response, heart rate, respiratory rate, and cloacal temperature were measured over a 15-minute period. Treatments were repeated after a minimum washout period of 7 days.
RESULTS Median onset of first sedation effects was 85 seconds (range, 60 to 120 seconds) for midazolam and 90 seconds (range, 45 to 180 seconds) for midazolam-butorphanol. Midazolam-butorphanol resulted in significantly less vigorous struggling during restraint than did midazolam or the control treatment. Heart rate did not differ significantly among treatments. The stress-induced increase in respiratory rate was significantly attenuated by midazolam and midazolam-butorphanol, whereas the increase in cloacal temperature was not attenuated by midazolam or midazolam-butorphanol.
CONCLUSIONS AND CLINICAL RELEVANCE Intranasal administration of midazolam and midazolam-butorphanol resulted in a rapid onset of sedation in cockatiels. Midazolam-butorphanol resulted in deeper sedation in both restrained and unrestrained birds than did midazolam alone. Midazolam and midazolam-butorphanol both provided safe and effective sedation in cockatiels.
Sedative and cardiopulmonary effects of buccally administered detomidine gel and reversal with atipamezole in dogs
Authors: Kasten Jennifer I. , Messenger Kristen M. , Campbell Nigel B. 
Published: November 2018

Abstract
OBJECTIVE To evaluate hemodynamic, respiratory, and sedative effects of buccally administered detomidine gel and reversal with atipamezole in dogs.
ANIMALS 8 adult purpose-bred dogs.
PROCEDURES Arterial and venous catheters were placed. Baseline heart rate, respiratory rate, cardiac output (determined via lithium dilution with pulse contour analysis), oxygen delivery, systemic vascular resistance, arterial blood gas values, and sedation score were obtained. Detomidine gel (2.0 mg/m2) was administered on the buccal mucosa. Cardiopulmonary data and sedation scores were obtained at predetermined times over 180 minutes. Atipamezole (0.1 mg/kg) was administered IM at 150 minutes. Reversal of sedation was timed and scored. Data were analyzed with an ANOVA.
RESULTS Compared with baseline values, heart rate was lower at 45 to 150 minutes, cardiac output and oxygen delivery were lower at 30 to 150 minutes, and systemic vascular resistance was increased at 30 to 150 minutes. There were no significant changes in Paco2, Pao2, or lactate concentration at any time point, compared with baseline values, except for lactate concentration at 180 minutes. All dogs became sedated; maximum sedation was detected 75 minutes after administration of detomidine. Mean ± SD time to recovery after atipamezole administration was 7.55 ± 1.89 minutes; sedation was completely reversed in all dogs. No adverse events were detected.
CONCLUSIONS AND CLINICAL RELEVANCE Buccally administered detomidine gel was associated with reliable and reversible sedation in dogs, with hemodynamic effects similar to those induced by other α2-adrenoceptor agonists. Buccally administered detomidine gel could be an alternative to injectable sedatives in healthy dogs.
Effect of a constant rate infusion of remifentanil hydrochloride on left ventricular systolic and diastolic function in propofol-anesthetized dogs
Authors: Marques Marcel G. , Cancelli Carlos H. B. , Fernandes Carollina M. S. , Games Bruna M. M. , Floriano Beatriz P. , Perri Silvia H. V. , Sousa Marlos G. , Ferreira Wagner L. , Santos Paulo S. P. 
Published: November 2018

Abstract
OBJECTIVE To assess the effects of a constant rate infusion (CRI) of remifentanil hydrochloride on left ventricular systolic and diastolic function in healthy propofol-anesthetized dogs.
ANIMALS 6 healthy Beagles.
PROCEDURES Each dog underwent 2 experimental treatments separated by a 7-day interval. In 1 treatment, anesthesia was induced with propofol and maintained with a CRI of propofol (0.6 mg/kg/min); dogs also received a CRI of saline (0.9% NaCl) solution. In the other treatment, anesthesia was similarly induced and maintained with propofol; dogs also received a CRI of remifentanil (0.3 μg/kg/min). Doppler echocardiographic and hemodynamic variables of interest were determined at baseline (before anesthesia) and at 20, 40, and 60 minutes following the simultaneous start of the 2 CRIs of each treatment; all CRIs were administrated for 60 minutes.
RESULTS For the 2 treatments, end-diastolic and end-systolic volume indices did not differ from baseline or at any time point. Peak tissue Doppler-derived mitral annulus systolic velocity decreased from baseline with both treatments; however, no differences were found between treatments at any time point. Mean arterial blood pressure decreased similarly with both treatments. Heart rate and Doppler-determined cardiac index decreased significantly with the propofol-remifentanil treatment, compared with findings for the propofol-saline solution treatment. For the propofol-remifentanil treatment, the ratio of peak velocity flow in early diastole to that in late diastole remained > 1.80, whereas the ratio of early to late Doppler-derived mitral annulus velocity had a normal relaxation pattern.
CONCLUSIONS AND CLINICAL RELEVANCE Results of this study indicated that a CRI of remifentanil administered along with a CRI of propofol does not impair left ventricular systolic and diastolic function in healthy dogs.
Activation of chicken macrophages during in vitro stimulation and expression of immune genes
Authors: Jin Xing , Zhang Xu , Li Jinchun , Yu Weiyi , Chen Fangfang 
Published: November 2018

Abstract
OBJECTIVE To characterize activation and expression of immune genes of chicken macrophages after in vitro stimulation with lipopolysaccharide (LPS) and mouse erythrocytes.
ANIMALS Five 15-day-old chickens and 2 BALB/c mice.
PROCEDURES Macrophages were extracted from chicken bone marrow or peripheral blood and then stimulated with cytokines secreted from cell lines L929 and HD11. Stimulated chicken macrophages were further cocultured with LPS or mouse erythrocytes, and gene transcription of some distinctive cytokines was detected by use of a real-time PCR assay.
RESULTS Morphological features and phagocytic function of macrophages were characterized. Activated macrophages had an elongated shape with a large cell nucleus, and they had phagocytic function. Distinctive genes encoding the surface marker gene CD11b were identified; high quantities of CD11b were transcribed. Relative transcription of chicken genes BF and BL in mature cells cocultured with both stimuli was lower than for control cells. However, the quantity of genes encoding M1- or M2-distinctive cytokines (interleukin [IL]-1β, IL-10, IL-12, inducible nitric oxide synthase, tumor necrosis factor-α, and transforming growth factor-β) that were transcribed differed significantly between stimulation with LPS and mouse erythrocytes.
CONCLUSIONS AND CLINICAL RELEVANCE Chicken macrophages were differentially stimulated by LPS and mouse erythrocytes, which suggested that in vitro stimulation can distinctly influence the transcription and expression of immune genes of chicken macrophages.
Effect of pneumoperitoneum with warmed humidified or standard-temperature carbon dioxide during laparoscopy on core body temperature, cardiorespiratory and thromboelastography variables, systemic inflammation, peritoneal response, and signs of postoperative pain in healthy mature dogs
Authors: Scott Jacqueline E. , Singh Ameet , Valverde Alexander , Blois Shauna L. , Foster Robert A. , Kilkenny Jessica J. , Linden Alex zur 
Published: November 2018

Abstract
OBJECTIVE To evaluate effects of pneumoperitoneum created with warmed humidified CO2 (WHCO2) during laparoscopy on core body temperature, cardiorespiratory and thromboelastography variables, systemic inflammation, peritoneal response, and signs of postoperative pain in healthy mature dogs.
ANIMALS 6 mature purpose-bred dogs.
PROCEDURES In a randomized crossover study, each dog was anesthetized twice, and pneumoperitoneum was created with standard-temperature CO2 (STCO2; 22°C and 0% relative humidity) and WHCO2 (37°C and 98% relative humidity). Data were collected during each procedure, including core body temperature, cardiorespiratory and thromboelastography variables, and inflammatory biomarkers. Peritoneal biopsy specimens were collected and evaluated with scanning electron microscopy. Dogs were assessed for signs of postoperative pain.
RESULTS Mean core body temperature was significantly lower (35.2°C; 95% confidence interval, 34.5° to 35.8°C) with WHCO2 than with STCO2 (35.9°C; 95% confidence interval, 35.3° to 36.6°C) across all time points. Cardiac index increased during the procedure for both treatments but was not significantly different between treatments. Thromboelastography variables did not differ significantly between treatments as indicated by the coagulation index. Subjective evaluation of peritoneal biopsy specimens revealed mesothelial cell loss with STCO2. There was no significant difference in circulating C-reactive protein or interleukin-6 concentrations. There was a significant increase in the number of postoperative pain scores > 0 for the WHCO2 treatment versus the STCO2 treatment.
CONCLUSIONS AND CLINICAL RELEVANCE Analysis of these data suggested that effects on evaluated variables attributable to the use of WHCO2 for creating pneumoperitoneum in healthy mature dogs undergoing laparoscopy did not differ from effects for the use of STCO2.
Study of the Effect of Sustainable Architecture on the Design of Residential Buildings (Case Study: Qazvin Pardis Complex)
Authors: Mohammadian Zeynab , Shahbazi Majid 
Published: November 2018

Abstract
Housing is a widespread and complex issue with a variety of dimensions. First, housing was considered as a physical location and as a shelter and basic necessity of the households, but today the concept of dwelling as the place that provides all the services and facilities necessary for a better life of the family has been created. One of the issues discussed at many conferences and in general in the scientific community is the definition of sustainability in the psychological point of view, along with the ways to introduce this concept into the architecture and human habitat environments. This research first begins with the main question about how the concept of sustainability can be found within the scope of housing. Then existing resources search is done and accessible projects are analyzed and the weaknesses and strengths of traditional architecture and contemporary architecture are compared. Finally, the relationship between the definitions of three concepts: dwelling, sustainable design and traditional Iranian architecture was discussed. At the end, the sustainable design that is also appropriate to the Iranian culture was presented.
Factors Associated with Mortality in Patients with a Solid Malignancy Admitted to the Intensive Care Unit - A Prospective Observational Study
Authors: Kingah Pascal , Alzubaidi Nasser , Yafawi Jihane Zaza Dit , Shehada Emad , Alshabani Khaled , Soubani Ayman O. 
Published: November 2018

Abstract

Purpose: Several studies show conflicting results regarding the prognosis and predictors of the outcome of critically ill patients with a solid malignancy. This study aims to determine the outcome of critically ill patients, admitted to a hospital, with a solid malignancy and the factors associated with the outcomes.

Methods and Materials: All patients with a solid malignancy admitted to an intensive care unit (ICU) at a tertiary academic medical center were enrolled. Clinical data upon admission and during ICU stay were collected. Hospital, ICU, and six months outcomes were documented.

Results: There were 252 patients with a solid malignancy during the study period. Urogenital malignancies were the most common (26.3%) followed by lung cancer (23.5%). Acute respiratory failure was the most common ICU diagnosis (51.6%) followed by sepsis in 46%. ICU mortality and hospital mortality were 21.8% and 34.3%. Six months mortality was 38.4%. Using multivariate analysis, acute kidney injury, OR 2.82, 95% CI 1.50-5.32 and P=0.001, use of mechanical ventilation, OR 2.67 95% CI 1.37 – 5.19 and P=0.004 and performance status of ≥2 with OR of 3.05, 95% CI of 1.5-6.2 and P= 0.002 were associated with hospital mortality. There were no differences in outcome between African American patients (53% of all patients) and other races.

Conclusion: This study reports encouraging survival rates in patients with a solid malignancy who are admitted to ICU. Patients with a poor baseline performance status require mechanical ventilation or develop acute renal failure have worse outcomes.
Antimicrobial Resistance of Enterococcus Faecium Isolated from the Urinary System Of Dogs
Authors: Kirkan Sukru , Parin Ugur , Balat Gamze 
Published: November 2018

Abstract
The purpose of the present study was to determine the antimicrobial susceptibility of vancomycin-resistant and Enterococcus faecium strains isolated from urine samples of dogs. A total of 22 Enterococcus sp. samples were isolated and identified from 100 urine samples collected by cystocentesis from dogs of both sexes. The identification with species specific primers for multiplex PCR revealed that all 22 isolates (100%) belonged to E. faecium. Vancomycin resistance was found in 10 (45%) samples of E. faecium strains with PCR study by vanA and vanB primers.
Tourism Sector in the European Union: Job Satisfaction of Employees in Hotels and Restaurants
Authors: Romero Virginia Navajas , Jimber del Río Juan Antonio , Casas-Rosal José Carlos 
Published: November 2018

Abstract
The main objective of this article is to analyze the degree of satisfaction of European Union workers, especially those working in the hotel and restaurant sector. The study is based on two phases: the first analyzes the number of workers in the EU between 2006 and 2017; a dynamic model for predicting the number of people working in hotels and restaurants has been created. In order to predict the number of workers in the studied sector, a dynamic model has been created based on a classical series estimation methodology. In the second phase, this study aims to measure the degree of satisfaction of these workers and the causes that affect them. A univariate and bivariate analysis has been used to describe satisfaction among hotel and restaurant workers and the relationship between this satisfaction and their working conditions. From the special characteristics observed in this sector, it can be deduced that the level of satisfaction expressed by the working conditions of the worker is significantly lower in the hotel and restaurant sector.
Preliminary Monitoring of Physico-Chemical Parameters of Water Wells from the Village of Bivolari (The Moldavian Plain)
Authors: Grigore Nepotu , Romanescu Gheorghe , Stoleriu Cristian Constantin 
Published: November 2018

Abstract
The main objective of the paper is focused on water quality research in the village of Bivolari, Iasi County. The Bivolari settlement is situated in the Prut meadow and develops along the road connecting Iasi and Stefanesti. The research done in this paper starts from the collection of data on water pH, water LDO (oxygen concentration), CDC (dissolved salt content) and water temperature. The parameters were measured for 7 months using the HACH-LANGE multiparameter of the Geoarchaeology Laboratory at Alexandru Ioan Cuza University of Iasi (Inter-disciplinary Platform ArheoInvest). The study is structured in two sections: scientific substantiation and applicative research. The scientific substantiation part analyzes the water features in the context of the integrated management approach as well as an analysis of the quality aspects of the water supply. The applied research part required monthly field measurements in 50 fountains (without the winter season). The approached subject is is complex and up-to-date because the citizen is a priority for EU Member States (EUPAN, 2009): the aspect of “customer satisfaction” represents a capital priority. Finally, the database is structured into two categories: spatial information such as maps; tabular information attached to spatial data. The paper also follows the transition from the field of research into the field of application by presenting models of data representation, which are at the same time tools adapted to the practical needs. In order to achieve this goal, the concept of quality (both in terms of product - drinking water and local consumer) is defined and addressed in an integrated manner. Of the 50 wells monitored, only one had a water shortage in the last 10 years, and in two other cases there were problems with household waste and dead animals that damaged the water supply. Some fountains can dry at intervals of 3-4 years.
Evaluation of Damages Caused by Floods, Based on Satellite Images. Case Study: Jijia River, Slobozia-Dângeni Sector, July 2010
Authors: Hutanu Elena , Urzica Andrei , Enea Andrei 
Published: November 2018

Abstract
This research aimed to identify flooded areas following the July 2010 floods, using Landsat 7-ETM + satellite imagery and a more efficient way to extract water bodies. By computing several indices, such as MNDWI, NDWI, NDVI, AWI, WRI and NDMI, it was concluded that, in the present case, the NDWI index was most effective, the data obtained having a very good accuracy. The studied area was the Jijia River Slobozia-Dângeni sector, the Landsat 7-ETM + images were taken on July 3, 2010. The flow rate at this time at the Dângeni station was 473 cm, decreasing compared to July 1, 2010 when the share reached 579 cm. The flooded area obtained is 15.80 km2, the maximum extension of the flood area on July 3, 2010 being approx. 1 km on the localities of Durneşti and Sapoveni. The study found 143 houses in 19 localities flooded. Of the total flooded areas, the largest share is held by arable land (44.58%), with a surface area of 7.04 km2.
Studies and Researches on Monitoring by GIS Models Extreme Phenomenons in the Popular Center
Authors: Lateș Iustina , Luca Alexandru-Lucian , Chirica Ștefania , Luca Mihail 
Published: November 2018

Abstract
The work involves the realization of a GIS model that includes both information on real estate cadastre and water supply networks. This shows the stages of making such a model, starting from field measurements, to structuring the database and custom layouts. In the study, the distribution pipelines equipped with fire hydrants and the existing building types in the area were considered as the main elements. Buildings were classified according to importance, height, destination, mapping indexes, etc. and have been integrated into the GIS model. GIS programs aim at specifying as much as possible the textual data attached to perform complex analyzes. Autocad and ArcMap programs allow you to get thematic maps on building types, pipeline network analysis on which hydrants are located, and how to protect firewalls. The study model was developed only for a sector in the city of Iaşi, but it can be extended to an application that can be used in other urban areas for the purpose of being used by the water-channel directorate, the intervention teams, the public administration local, etc.
Mapping Snow for Area Where was Detected Ground Deplacement: A Case Studi of Iaşi County
Authors: Macarof Paul , Lazăr Cezarina Georgiana Bartic , Statescu Florian 
Published: November 2018

Abstract
The main goal of this paper is to detect snow in areas where was detecting and mapping, using Differential Radar Interferometry (DInSAR) technique, ground displacement. DInSAR is a powerful tool to detect and monitor ground deformation. Iaşi county is considered as study area in this research. Study area is geographically situated on latitude 46°48’N to 47°35’N and longitude 26°29’E to 28°07’E. For this paper, to detect and mapping grond displacement, was used Sentinel – 1 images, provided free by The European Space Agency (ESA), for January 2018, with vertical polarization (VV), ascending orbit and Interferometric Wide swath (IW) mode operated. SNAP was used to process the Sentinel – 1 images. Landsat-8 OLI was taken to detect areas cover with snow using Normalized Difference Snow Index (NDSI) - a numerical indicator that shows snow cover over land areas. ArcMap was used to create NDSI map after Landsat-8 data was preprocessed. The presence of snow has been observed both in the areas where it exists vertical displacement positive and negative.
Impact analysis of observation coupling on reliability indices in a geodetic network
Authors: Nowak Edward , Odziemczyk Waldemar 
Published: November 2018

Abstract
An optimally designed geodetic network is characterised by an appropriate level of precision and the lowest possible setup cost. Reliability, translating into the ability to detect blunders in the observations and higher certainty of the obtained point positions, is an important network characteristic. The principal way to provide appropriate network reliability is to acquire a suitably large number of redundant observations. This approach, however, faces limitations resulting from the extra cost. This paper analyses the possibility of providing appropriate reliability parameters for networks with moderate redundancy. A common problem in such cases are dependencies between observations preventing the acquisition of the required reliability index for each of the individual observation. The authors propose a methodology to analyse dependencies between observations aiming to determine the possibility of acquiring the optimal reliability indices for each individual observation or groups of observations. The suggested network structure analysis procedures were illustrated with numerical examples.
Headframe modelling accuracy for finite element method analysis purposes
Authors: Biel Damian , Lipecki Tomasz 
Published: November 2018

Abstract
Nowadays, the growing popularity of terrestrial laser scanners (TLS) allows to obtain a point cloud of many industrial objects along with classic surveying. However, the quality and model’s accuracy in comparison to a real shape seem to be a question, that must be further researched. It is crucial especially for Finite Element Method (FEM) analysis, which, being a part of technical design, estimate the values of construction’s dislocation and deformation. The article describes objects such as headgear with steel support and 4-post headframe with steel sheers. Both supports and sheers were modelled basing on point clouds. All the models were compared to the point cloud. The differences in models’ shape were calculated and the maximal values were determined. The results’ usefulness in FEM analysis was described.