bluuebunny/crossref_metadata_2025_split huggingface dataset:
Opponent neurochemical and functional processing in NREM and REM sleep in visual learning
Authors: Tamaki Masako , Wang Zhiyan , Barnes-Diana Tyler , Berard Aaron V. , Walsh Edward , Watanabe Takeo , Sasaki Yuka 
Published: August 2019

AbstractSleep is beneficial for learning. However, whether NREM or REM sleep facilitates learning, whether the learning facilitation results from plasticity increases or stabilization and whether the facilitation results from learning-specific processing are all controversial. Here, after training on a visual task we measured the excitatory and inhibitory neurochemical (E/I) balance, an index of plasticity in human visual areas, for the first time, while subjects slept. Off-line performance gains of presleep learning were associated with the E/I balance increase during NREM sleep, which also occurred without presleep training. In contrast, increased stabilization was associated with decreased E/I balance during REM sleep only after presleep training. These indicate that the above-mentioned issues are not matters of controversy but reflect opposite neurochemical processing for different roles in learning during different sleep stages: NREM sleep increases plasticity leading to performance gains independently of learning, while REM sleep decreases plasticity to stabilize learning in a learning-specific manner.
Reward does not facilitate visual perceptual learning until sleep occurs
Authors: Tamaki Masako , Berard Aaron V. , Barnes-Diana Tyler , Siegel Jesse , Watanabe Takeo , Sasaki Yuka 
Published: August 2019

ABSTRACTA growing body of evidence indicates that visual perceptual learning (VPL) is enhanced by reward provided during training. Another line of studies has shown that sleep following training also plays a role in facilitating VPL, an effect known as the offline performance gain of VPL. However, whether the effects of reward and sleep interact on VPL remains unclear. Here, we show that reward interacts with sleep to facilitate offline performance gains of VPL. First, we demonstrated a significantly larger offline performance gain over a 12-h interval including sleep in a reward group than that in a No-reward group. However, the offline performance gains over the 12-h interval without sleep were not significantly different with or without reward during training, indicating a crucial interaction between reward and sleep in VPL. Next, we tested whether neural activations during posttraining sleep were modulated after reward was provided during training. Reward provided during training enhanced REM sleep time, increased oscillatory activities for reward processing in the prefrontal region during REM sleep, and inhibited neural activation in the untrained region in early visual areas in NREM and REM sleep. The offline performance gains were significantly correlated with oscillatory activities of visual processing during NREM sleep and reward processing during REM sleep in the reward group but not in the No-reward group. These results suggest that reward provided during training becomes effective during sleep, with excited reward processing sending inhibitory signals to suppress noise in visual processing, resulting in larger offline performance gains over sleep.Significance statementIndependent lines of research have shown that visual perceptual learning (VPL) is improved by reward or sleep. Here, we show that reward provided during training increased offline performance gains of VPL over sleep. Moreover, during posttraining sleep, reward was associated with longer REM sleep, increased activity in reward processing in the prefrontal region during REM sleep, and decreased activity in the untrained region of early visual areas during NREM and REM sleep. Offline performance gains were correlated with modulated oscillatory activity in reward processing during REM sleep and visual processing during NREM sleep. These results suggest that reward provided during training becomes effective on VPL through the interaction between reward and visual processing during sleep after training.
Reduced firing rates of pyramidal cells in frontal cortex of APP/PS1 can be restored by acute treatment with levetiracetam
Authors: Klee Jan L. , Kiliaan Amanda J , Lipponen Arto , Battaglia Francesco P. 
Published: August 2019

AbstractIn recent years aberrant neural oscillations in various cortical areas have emerged as a common physiological hallmark across mouse models of amyloid pathology and patients with Alzheimer’s disease. However, much less is known about the underlying effect of amyloid pathology on single cell activity. Here, we used high density silicon probe recordings from frontal cortex area of 9 months old APP/PS1 mice to show that resting state Local Field Potential (LFP) power in the theta and beta band is increased in transgenic animals, while single cell firing rates, specifically of putative pyramidal cells, are significantly reduced. At the same time, these sparsely firing pyramidal cells phase-lock their spiking activity more strongly to the ongoing theta and beta rhythms. Furthermore, we demonstrated that the anti-epileptic drug, levetiracetam, can restore principal cell firing rates back to control levels. Overall, our results highlight reduced firing rates of cortical pyramidal cells as a symptom of amyloid pathology and indicate that lifting cortical inhibition might contribute to the beneficial effects of levetiracetam on AD patients.Abstract Figure
A SAC phosphoinositide phosphatase controls rice development via hydrolyzing phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate
Authors: Guo Tao , Chen Hua-Chang , Lu Zi-Qi , Diao Min , Chen Ke , Dong Nai-Qian , Shan Jun-Xiang , Ye Wang-Wei , Huang Shanjin , Lin Hong-Xuan 
Published: August 2019

AbstractPhosphoinositides (PIs) as regulatory membrane lipids play essential roles in multiple cellular processes. Although the exact molecular targets of PIs-dependent modulation remain largely elusive, the effects of disturbed PIs metabolism could be employed to propose regulatory modules associated with particular downstream targets of PIs. Here, we identified the role of GRAIN NUMBER AND PLANT HEIGHT 1 (GH1), which encodes a suppressor of actin (SAC) domain-containing phosphatase with unknown function in rice. Endoplasmic reticulum-localized GH1 specifically dephosphorylated and hydrolyzed phosphatidylinositol 4-phosphate (PI4P) and phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]. Inactivation of GH1 resulted in massive accumulation of both PI4P and PI(4,5)P2, while excessive GH1 caused their depletion. Notably, superabundant PI4P and PI(4,5)P2 could both disrupt actin cytoskeleton organization and suppress cell elongation. Interestingly, both PI4P and PI(4,5)P2 inhibited actin-related proteins 2 and 3 (Arp2/3) complex-nucleated actin branching networks in vitro, whereas PI(4,5)P2 showed more dramatic effect in a dose-dependent manner. Overall, the overaccumulation of PI(4,5)P2 resulted from dysfunction of SAC phosphatase possibly perturbs Arp2/3 complex-mediated actin polymerization, thereby disordering the cell development. These findings imply that Arp2/3 complex might be the potential molecular target of PI(4,5)P2-dependent modulation in eukaryotes, thereby providing new insights into the relationship between PIs homeostasis and plants growth and development.
State investments and human rights? The case of the Norwegian Government Pension Fund Global
Authors: Kreander Niklas , McPhail Ken 
Published: August 2019

PurposeThe purpose of this paper is to explore how the Norwegian Government incorporated its responsibility for human rights into the investment practices of its Global Pension Fund and how human rights issues were negotiated when exclusion was considered.Design/methodology/approachDrawing on a series of interviews the authors analyse the way in which responsibility for human rights has been translated into the practices of the Norwegian Government Pension Fund Global.FindingsThe paper documents how a large investment fund used several mechanisms to address human rights risks. The authors demonstrate that different logics among actors sometimes impeded addressing human rights issues. The findings demonstrate that sovereign wealth funds (SWF) can be held accountable for human rights.Research limitations/implicationsThe paper illustrates the difficulty of co-operation between actors with different logics. This can result in institutional conflict, but also in positive outcomes for human rights.Practical implicationsAttempts to introduce human rights into state investments may result in increased institutional complexity. The findings indicate that state investors can address human rights issues, but that the ability to do so is diminished where divestment creates political tension.Social implicationsLarge investors can influence companies on specific human rights issues.Originality/valueThis is one of the first empirical investigations of the human rights practices of a SWF. The authors contribute to the literatures on accounting and human rights, SWF and institutional theory.
Supersonic jet flow control using semi-circular corrugated tabs
Authors: K. Sathish Kumar , Chidambaram Senthilkumar 
Published: August 2019

Purpose
The purpose of this study is to increase the jet mixing effectiveness of Mach 1.6 axisymmetric jet using semi-circular corrugated triangular tabs (Tabs A, B and C), in which the locations of the semi-circular corrugations are varied along the leaned sides of the triangular tabs.

Design/methodology/approach
The tabs are fixed at the exit of the nozzle facing each other 180° apart. To quantify the jet mixing effectiveness of the semi-circular corrugated tabs, Pitot pressure measurements were carried out for the cases of over-expansion, marginally over-expansion and under-expansion levels of Mach 1.6 jet, along the jet centerline and the jet spread, along and normal to the tab axis.

Findings
The results exhibit that the semi-circular corrugated Tab A augments the jet mixing when compared to Tabs B and C. This impact in jet mixing is strongly due to the small-scale vortices shed from the tabs and the mixed effect of the corrugation locations and expansion ratio. The maximum percentage reduction in core length is about 73.6 per cent for the jet with semi-circular corrugated Tab A at NPR 5, whereas it is 71.4 and 67.1 per cent for Tabs B and C, respectively.

Practical implications
The reduction in core length of the jet with minimum thrust loss is obtained by controlling the jet used with semi-circular corrugated triangular tabs of equal blockage ratio 5.12 per cent with respect to the nozzle exit diameter.

Originality/value
The locations of the semi-circular corrugations varied systematically at the equally leaned sides of the triangular tab ensure the novelty of this study.
Aerodynamic benefits of boundary layer ingestion for distributed propulsion configuration
Authors: Zhang Jing , Kang Wenwen , Yang Lingyu 
Published: August 2019

Purpose
Boundary layer ingestion (BLI) is one of the probable noteworthy features of distributed propulsion configuration (DPC). Because of BLI, strong coupling effects are generated between the aerodynamics and propulsion system of aircraft, leading to the specific lift and drag aerodynamic characteristics. This paper aims to propose a model-based comprehensive analysis method to investigate this unique aerodynamic.

Design/methodology/approach
To investigate this unique aerodynamics, a model-based comprehensive analysis method is proposed. This method uses a detailed mathematical model of the distributed propulsion system to provide the essential boundary conditions and guarantee the accuracy of calculation results. Then a synthetic three-dimensional computational model is developed to analyze the effects of BLI on the lift and drag aerodynamic characteristics.

Findings
Subsequently, detailed computational analyses are conducted at different flight states, and the regularities under various flight altitudes and velocities are revealed. Computational results demonstrate that BLI can improve the lift to drag ratio evidently and enable a great performance potentiality.

Practical implications
The general analysis method and useful regularities have reference value to DPC aircraft and other similar aircrafts.

Originality/value
This paper proposed a DPS model-based comprehensive analysis method of BLI benefit on aerodynamics for DPC aircraft, and the unique aerodynamics of this new configuration under various flight altitudes and velocities was revealed.
Building high performance supply-chain relationships for dynamic environments
Authors: Ahmed Muhammad Usman , Kristal Mehmet Murat , Pagell Mark , Gattiker Thomas F. 
Published: August 2019

PurposeThe purpose of this paper is to explore how different forms of integration interact with environmental dynamism to influence the outcomes of a buyer–supplier relationship (BSR). Specifically, the authors assess the impact of communication, operational process integration (OPI) and joint knowledge exploration (JKE) on the economic value and competitive differentiation generated by the BSR. Furthermore, the authors assess the moderating role of environmental dynamism in changing the performance implications of these different forms of integration.Design/methodology/approachThe authors empirically test the theoretical model using survey data collected from North America. The authors apply techniques such as confirmatory factor analysis, regression and a variety of robustness checks to ensure the validity of the findings.FindingsThe results indicate that OPI and JKE are useful in generating higher value from key supply chain relationships. However, communication does not directly influence performance outcomes, rather it assists in the implementation of other forms of integration. In stable environments, better returns can be obtained from focusing on OPI, while in dynamic environments JKE becomes far more important.Originality/valueThis study shows that different aspects of integration have very different performance implications and that selective integration can outperform broad-based integration in some conditions. More importantly, the performance implications depend on environmental dynamism in unique ways, where greater integration is not always the best response to dynamic business conditions. The results allow managers to make better decisions regarding what forms of integration to establish in key supply chain relationships.
Applications of business governance and the Unified BPM Cycle in public credit recovery activities
Authors: Nascimento Abimael Rondon Do , Baldam Roquemar de Lima , Costa Lourenço , Coelho Junior Thalmo de Paiva 
Published: August 2019

PurposeThe performance of the state machine has been the subject of research and innovative practices, which seek to explore its sources of knowledge and improve its internal processes. Business governance and business process management (BPM) occupy a prominent position in these studies. The purpose of this paper is to analyze the full implementation of the Unified BPM Cycle in operational activities to recover federal public credit, from the implementation of the corporate governance structure to the audit of the processes implemented.Design/methodology/approachThe case was developed in a federal public advocacy body and used a predominantly qualitative multi-method approach. The phases were organized using the research project matrix, and the predominant research procedure was action research. The information was obtained through questionnaires, observation and focus groups.FindingsA corporate governance structure was designed for the activities surveyed. Papers and responsibilities were defined. Processes were prioritized, improved and documented, and as a result of the implemented control, personal and organizational results gained greater visibility.Research limitations/implicationsBecause this is a single case study, it would be advisable to apply the method used in similar organizations to enrich the analysis presented in this study and compare the results.Practical implicationsThis paper contributes to the consolidation of the knowledge about the practical application of the researched subjects and foments the applied research to the public management.Originality/valueThis paper describes an empirical case study about the integrated application of activity governance and the Unified BPM Cycle in operational activities and studies all phases of implementation, providing a broader perspective of their impact on these activities. The road map used can serve as a reference for future research in the area of public credit recovery.
Hybrid approach to reducing estimating overfitting and collinearity
Authors: Xiong Bo , Newton Sidney , Li Vera , Skitmore Martin , Xia Bo 
Published: August 2019

Purpose
The purpose of this paper is to present an approach to address the overfitting and collinearity problems that frequently occur in predictive cost estimating models for construction practice. A case study, modeling the cost of preliminaries is proposed to test the robustness of this approach.

Design/methodology/approach
A hybrid approach is developed based on the Akaike information criterion (AIC) and principal component regression (PCR). Cost information for a sample of 204 UK school building projects is collected involving elemental items, contingencies (risk) and the contractors’ preliminaries. An application to estimate the cost of preliminaries for construction projects demonstrates the method and tests its effectiveness in comparison with such competing models as: alternative regression models, three artificial neural network data mining techniques, case-based reasoning and support vector machines.

Findings
The experimental results show that the AIC–PCR approach provides a good predictive accuracy compared with the alternatives used, and is a promising alternative to avoid overfitting and collinearity.

Originality/value
This is the first time an approach integrating the AIC and PCR has been developed to offer an improvement on existing methods for estimating construction project Preliminaries. The hybrid approach not only reduces the risk of overfitting and collinearity, but also results in better predictability compared with the commonly used stepwise regression.
Institutional influences on firm strategy in authoritarian emerging economies
Authors: Wilkins Stephen , Emik Serap 
Published: August 2019

PurposeThis is one of the first studies to investigate the influences of institutions in an authoritarian regime on the strategies of firms that operate in a potentially sensitive industry. The purpose of this paper is to examine how institutional pressures affect the strategies of multi-platform mass media companies (print, broadcast and internet) in the United Arab Emirates (UAE).Design/methodology/approachThis qualitative study used a purposive sampling strategy to conduct interviews with 28 senior managers who have responsibility for strategic level decision making in a UAE media company. All of the interviews were audio recorded and transcribed. A mainly deductive process of thematic analysis was undertaken to identify key ideas, patterns and relationships in the data.FindingsThe survey participants reported that increased multi-platform delivery in the media industry brings rewards, challenges and new risks. Although the normative and cultural-cognitive pressures are both strong in the UAE, it is the regulative pressures that seem to have the largest constraining influence on firm decision making and business strategies. The strong institutional pressures existing in the UAE encourage tight coupling, where firm structures and processes are linked and designed in response to the institutional constraints. Evidence was found only of some minor decoupling.Originality/valueIn response to the authors’ findings, the authors hypothesise that in nations under authoritarian rule, political pressures will likely override all other institutional pressures and that it will be most sensible for firms to adopt tight coupling strategies. However, the success of many UAE firms both at home and internationally suggests that strong institutional constraints do not necessarily act as a barrier to superior firm performance.
Exploring blockchain technology in international trade
Authors: Chang Shuchih Ernest , Chen Yi-Chian , Wu Tzu-Ching 
Published: August 2019

Purpose
The purpose of this paper is to explore the applicability of blockchain technology in international trade process from a perspective of letter of credit payment.

Design/methodology/approach
A blockchain-based re-engineering process is designed by employing the blockchain and its affiliated smart contract technology to harvest the benefits of distributed ledger and distributed business workflow automation.

Findings
Comparative analysis and feasibility study were conducted to identify and validate the prospects, in terms of facilitating process flow and enhancing overall trade performance, of the proposed blockchain-based international trade process model.

Practical implications
Traditional trade processes suffer from a great number of issues about intermediaries, information latency and trust, which, in turn, hinder overall process efficiency. The emerging blockchain technology may have potentials to mitigate those issues by revolutionizing business processes across enterprise borders in various industries.

Originality/value
This study contributes to the conceptual design of a blockchain- and smart-contract-based process along with a provision of practical case in business process re-engineering. Further endeavors devoted to blockchain research and application across different sectors are suggested to reach better performance of business process operations.
Exploring relationship between value perception and luxury purchase intention
Authors: Jain Sheetal 
Published: August 2019

Purpose
Although India is home to the world’s largest millennial population, so far, hardly any studies exist that explain the key drivers leading to the luxury goods consumption among this generational cohort. Therefore, the purpose of this paper is twofold: first, to develop and empirically test the conceptual framework designed to measure the relationship between luxury value perceptions and purchase intentions among the young Indian luxury consumers, and, second, to examine the moderating effect of gender in the relationship between luxury value perceptions and purchase intentions.

Design/methodology/approach
A purposive sampling technique was employed to collect the data from young luxury fashion consumers. Statistical tests including confirmatory factor analysis, multi-group analysis and structural equation modeling were applied for data analysis.

Findings
The findings show that the conspicuous value is the most significant determinant of luxury purchase intention followed by the experiential value, susceptibility to normative influence and utilitarian value. The uniqueness value was found to have weak relationship with purchase intention. Furthermore, results revealed that the relationship between the luxury values and the luxury buying intentions does not vary significantly between male and female.

Originality/value
This is one of the first studies that provides meaningful insights to the academicians and marketing practitioners about why millennials buy luxury fashion brands in emerging markets like India.