bluuebunny/crossref_metadata_2025_split huggingface dataset:
Building or Extending a Hospital Department: Radiology a Path through the Planning Minefield (9)
Authors: Roebuck E J , Manton D J , Fordham G L 
Published: March 2018

This is the ninth of a series often articles on the planning and building of a new radiology department or the extension of an old one. While the series focuses on a radiology department, it will be of interest to anyone who is planning any part of a hospital, particularly in the detailed information about the planning process and the part to be played by hospital staff during the subsequent building and commissioning. An expanded version of this series is to be published as a book in 1988 by the Royal Society of Medicine, and will include a comprehensive index.
Undergraduate clinical neurosciences programme development: A consumer-based evaluation
Authors: Gledhill R F 
Published: March 2018

Intern responses to a questionnaire were used to evaluate an undergraduate clinical neurosciences programme. The data obtained were judged an authentic measure of instructional efficacy. Most interns rated themselves competent in performing the neurological examination but ill-equipped to interpret their findings and to manage effectively common problems, especially emergencies. Neurological diseases and the non-biomedical aspects of patient care were identified relatively infrequently as matters needing greater emphasis. Explanations for these findings may include a curriculum of traditional format, differences in teaching and assessing theoretical and practical competence, and the typical responsibilities of interns in an academic hospital. Intern evaluation of undergraduate clinical programmes can provide data useful to their development.
Building or Extending a Hospital Department: Radiology a Path through the Planning Minefield (10)
Authors: Roebuck E J , Manton D J , Fordham G L 
Published: March 2018

This is the last of a series of ten articles on the planning and building of a new radiology department or the extension of an old one. While the series focuses on a radiology department, it will be of interest to anyone who is planning any part of a hospital, particularly in the detailed information about the planning process and the part to be played by hospital staff during the subsequent building and commissioning. An expanded version of this series is to be published as a book in 1988 by the Royal Society of Medicine, and will include a comprehensive index.
Intra-Operative Parathyroid Hormone Assay for Simplified Localization of Parathyroid Adenomas
Authors: Saharay M , Farooqui A , Farrow S , Fahie-Wilson M , Brown A 
Published: March 2018

Lack of success in parathyroid surgery is usually due to failure to identify the abnormal parathyroid gland correctly at operation. The surgeon may be helped by rapid parathyroid hormone (PTH) assay in peripheral blood after removal of a suspected adenoma, and by frozen section histology, but these are not true localization techniques. We have adapted a non-isotopic immunoassay for rapid measurement of PTH in samples from the upper, middle and lower thyroid veins taken at operation, before exploration begins. Fifteen patients with primary hyperparathyroidism were operated on. In 10 the parathyroid adenoma was located easily, and was associated with high local venous PTH levels. In four patients the abnormal parathyroid was not immediately apparent but the assay indicated its location, which was confirmed after further exploration. In one patient there was no difference in PTH levels in the six venous samples. An ectopic adenomatous gland was successfully identified behind the thymus. The operation was successful in all patients as shown by a fall in the plasma calcium to the normal range. We conclude that intra-operative selective venous sampling and rapid PTH assay facilitates operative localization of parathyroid adenomas.
Can Acupuncture have Specific Effects on Health? A Systematic Review of Acupuncture Antiemesis Trials
Authors: Vickers Andrew J 
Published: March 2018

The effects of acupuncture on health are generally hard to assess. Stimulation of the P6 acupuncture point is used to obtain an antiemetic effect and this provides an excellent model to study the efficacy of acupuncture. Thirty-three controlled trials have been published worldwide in which the P6 acupuncture point was stimulated for treatment of nausea and/or vomiting associated with chemotherapy, pregnancy, or surgery. P6 acupuncture was equal or inferior to control in all four trials in which it was administered under anaesthesia; in 27 of the remaining 29 trials acupuncture was statistically superior. A second analysis was restricted to 12 high-quality randomized placebo-controlled trials in which P6 acupuncture point stimulation was not administered under anaesthesia. Eleven of these trials, involving nearly 2000 patients, showed an effect of P6. The reviewed papers showed consistent results across different investigators, different groups of patients, and different forms of acupuncture point stimulation. Except when administered under anaesthesia, P6 acupuncture point stimulation seems to be an effective antiemetic technique. Researchers are faced with a choice between deciding that acupuncture does have specific effects, and changing from ‘Does acupuncture work?’ to a set of more practical questions; or deciding that the evidence on P6 antiemesis does not provide sufficient proof, and specifying what would constitute acceptable evidence.
An Analysis of Telephone Calls to an Inner-City Accident and Emergency Department
Authors: Crouch Robert , Patel Anita , Williams Susan , Dale Jeremy 
Published: March 2018

The general public in the UK often telephone accident and emergency (A&E) departments for medical advice. Such calls are usually dealt with by nursing staff in an informal manner (often with no written record of the call being made). The specific questions addressed in this study are who was calling for advice, when did they call, what were their presenting complaints, and what was the outcome of the call? In addition, the study provided an opportunity to test the implementation of a new system of record-keeping for telephone consultation. A telephone consultation record (TCR) was developed and used to record details of each call made to the A&E department for medical/health advice. An analysis of 597 consecutive documented calls is presented in this paper. The majority of calls were dealt with by ‘E’ grade nursing staff (42.7%); only four calls (0.7%) were recorded by medical staff. Two hundred and six (43.5%) calls related to patients aged up to 15 years. In 57% of the cases the call was made by a third party. In all, 149 different presenting complaints were recorded on the TCRs. The three most common presenting complaints were dental problems (7.4%), fever (4.3%), and concerns about drug reactions (23%). Seventy-three per cent of callers were advised that a visit to the A&E department was not immediately necessary. The study identifies several important issues for development of a more formal and effective system of telephone advice. The majority of calls made to the A&E department appeared to be of a primary care nature but the extent to which nurses are trained to assess and advise on these problems needs to be questioned. A reluctance to document the calls to A&E was identified, one reason being a concern about accountability. Training and support are clearly required.
Seroprevalence of Hepatitis B and C Virus in Two Institutions Caring for Mentally Handicapped Adults
Authors: Cramp M E , Grundy H C , Perinpanayagam R M , Barnado D E 
Published: March 2018

Hepatitis B virus infection is common in institutions caring for the mentally handicapped. Hepatitis B virus and hepatitis C virus share routes of transmission but the prevalence of hepatitis C virus infection in this population is unknown. We have tested 101 patients from two institutions in South-East England caring for adults with mental handicap for the presence of hepatitis C antibody, hepatitis B core antibody, and if necessary hepatitis B surface antigen. None tested positive for hepatitis C antibody, but 43 had hepatitis B core antibody of whom 14 were chronic carriers positive for hepatitis B surface antigen. Unlike hepatitis B virus, hepatitis C virus infection appears to be uncommon in UK institutions.
Do Community Hospitals Reduce the Use of District General Hospital Inpatient beds?
Authors: Hine Christine , Wood Victorine A , Taylor Stephen , Charny Mark 
Published: March 2018

Community hospitals have been supported by the general public and by professionals as one means of increasing choice between local, low technology, care and high technology care at the district general hospital. However, there is no information on the impact of community hospitals on district general hospital use subsequent to NHS and community care reforms. Examination of routinely gathered activity data in the Bath Health District revealed that availability of community hospital beds was associated with reduced use of central inpatient services in the city of Bath. The reduction was most apparent for medical and geriatric beds. Decrease in the use of surgical beds was small. However, total inpatient bed use (including central and community hospital beds) was higher in the population with access to community hospital beds. We conclude that community hospitals offer one option for accessible health care and, as such, merit systematic evaluation of costs and benefits. This study presents some evidence that savings could be achieved through improved efficiency.
Towards a framework to evaluate the ‘total’ performance of buildings
Authors: Taylor Jonathon , Liu Yanchen , Lin Borong , Burman Esfand , Hong Sung-Min , Yu Juan , Wang Zhe , Mumovic Dejan , Shrubsole Clive , Vermeer Daan , Davies Mike 
Published: March 2018

Internationally, buildings are a major contributor to carbon emissions. Despite significant advances in the technology and construction of energy-efficient buildings, in many cases a performance gap between designed and actual performance exists. While much research has investigated the drivers of the building energy performance gap – both static and transient– there has been considerably less research into the total performance gap, defined here as performance gaps in building energy use, occupant satisfaction and Indoor Environmental Quality parameters such as thermal comfort and air quality which may impact on occupant health and wellbeing. This paper presents a meta-analysis of building performance data from buildings in the UK and China – selected due to their contrasting development environments – which illustrate the presence of and complexities of evaluating total performance gaps in both countries. The data demonstrate the need for (1) high end-use, spatial granularity and temporal resolution data for both energy and Indoor Environmental Quality, and (2) developing methodologies that allow meaningful comparisons between buildings internationally to facilitate learning from successful building design, construction methodologies and policy environments internationally. Using performance data from a UK building, a potential forward path is illustrated with the objective of developing a framework to evaluate total building performance. Practical application: While much research has examined building energy performance gaps, Indoor Environmental Quality and occupant satisfaction gaps are rarely included despite their relationship to energy. We use a meta-analysis of energy, indoor environmental quality, and occupant satisfaction data from buildings in the UK and China to illustrating the presence of and complexities of evaluating total performance gaps for buildings in the two countries, and the need for high resolution dynamic buildings data and novel methodologies for comparison between buildings across different contexts. Illustrative case studies are used to demonstrate potential future directions for evaluating ‘total’ building performance.
Efficacy and safety of peripherally inserted central venous catheters in acute cardiac care management
Authors: Poletti Fabrizio , Coccino Claudio , Monolo Davide , Crespi Paolo , Ciccioli Giorgio , Cordio Giuseppe , Seveso Giovanni , De Servi Stefano 
Published: March 2018

Purpose: Patients admitted to cardiac intensive care unit need administration of drugs intravenously often in concomitance of therapeutic techniques such as non-invasive ventilation, continuous renal replacement therapy and intra-aortic balloon counterpulsation. Therefore, the insertion of central venous catheters provides a reliable access for delivering medications, laboratory testing and hemodynamic monitoring, but it is associated with the risk of important complications. In our study, we tested the efficacy and safety of peripherally inserted central catheters to manage cardiac intensive care. Methods: All patients admitted to cardiac intensive care unit with indication for elective central venous access were checked by venous arm ultrasound for peripherally inserted central catheter’s implantation. Peripherally inserted central catheters were inserted by ultrasound-guided puncture. After 7 days from the catheter’s placement and at the removal, vascular ultrasound examination was performed searching signs of upper extremity deep venous thrombosis. In case of sepsis, blood cultures peripherally from the catheter and direct culture of the tip of the catheter were done to establish a catheter-related blood stream infection. Results: In our cardiac intensive care unit, 137 peripherally inserted central catheters were placed: 80.3% of patients eligible for a peripherally inserted central catheter were implanted. The rate of symptomatic catheter-related peripheral venous thrombosis was 1.4%. Catheter-related blood stream infection was diagnosed in one patient (0.7%; 5.7 × 1000 peripherally inserted central catheter days). All peripherally inserted central catheters were inserted successfully without other major complications. Conclusions: In patients admitted to cardiac intensive care unit, peripherally inserted central catheters’ insertion was feasible in a high percentage of patients and was associated with low infective complications and clinical thrombosis rate.
Assessment and prediction of road accident injuries trend using time-series models in Kurdistan
Authors: Parvareh Maryam , Karimi Asrin , Rezaei Satar , Woldemichael Abraha , Nili Sairan , Nouri Bijan , Nasab Nader Esmail 
Published: March 2018

Abstract

Background
Road traffic accidents are commonly encountered incidents that can cause high-intensity injuries to the victims and have direct impacts on the members of the society. Iran has one of the highest incident rates of road traffic accidents. The objective of this study was to model the patterns of road traffic accidents leading to injury in Kurdistan province, Iran.

Methods
A time-series analysis was conducted to characterize and predict the frequency of road traffic accidents that lead to injury in Kurdistan province. The injuries were categorized into three separate groups which were related to the car occupants, motorcyclists and pedestrian road traffic accident injuries. The Box-Jenkins time-series analysis was used to model the injury observations applying autoregressive integrated moving average (ARIMA) and seasonal autoregressive integrated moving average (SARIMA) from March 2009 to February 2015 and to predict the accidents up to 24 months later (February 2017). The analysis was carried out using R-3.4.2 statistical software package.

Results
A total of 5199 pedestrians, 9015 motorcyclists, and 28,906 car occupants’ accidents were observed. The mean (SD) number of car occupant, motorcyclist and pedestrian accident injuries observed were 401.01 (SD 32.78), 123.70 (SD 30.18) and 71.19 (SD 17.92) per year, respectively. The best models for the pattern of car occupant, motorcyclist, and pedestrian injuries were the ARIMA (1, 0, 0), SARIMA (1, 0, 2) (1, 0, 0)12, and SARIMA (1, 1, 1) (0, 0, 1)12, respectively. The motorcyclist and pedestrian injuries showed a seasonal pattern and the peak was during summer (August). The minimum frequency for the motorcyclist and pedestrian injuries were observed during the late autumn and early winter (December and January).

Conclusion
Our findings revealed that the observed motorcyclist and pedestrian injuries had a seasonal pattern that was explained by air temperature changes overtime. These findings call the need for close monitoring of the accidents during the high-risk periods in order to control and decrease the rate of the injuries.
Experiences and learnings from induced seismicity regulation in Alberta
Authors: Shipman Todd , MacDonald Ron , Byrnes Tom 
Published: March 2018

We have examined the experiences and learnings acquired through the implementation of the Alberta Energy Regulator’s (AER) subsurface order no. 2 (sub or no. 2) traffic light protocol (TLP). On 22 January 2015, a 4.4 [Formula: see text] seismic event occurred near a hydraulic fracturing operation in west-central Alberta and was felt by residents of the town of Fox Creek. On 19 February 2015, the AER issued sub or no. 2 to help manage induced seismicity, as related to hydraulic fracturing of the Duvernay zone in a prescribed area around Fox Creek. Sub or no. 2 requires operators affected by the order to conduct a seismic hazard assessment; prepare a monitoring, mitigation, and response plan; conduct seismic monitoring; and adhere to a TLP. Since sub or no. 2 was issued, two “red light” events (i.e., [Formula: see text]) have occurred in the area. Review and analysis of data and information collected under sub or no. 2 facilitate an improved understanding of the key geologic and operational controls on induced seismicity and allow for an assessment of the efficacy of industry practices and regulatory requirements. We still support the use of local magnitude [Formula: see text] for our TLP based on the purpose and outcomes provided by sub or no. 2. Conversations with operators have suggested that [Formula: see text] orientation should inform the wells’ trajectory with respect to critically stressed faults. The requirement of a response plan was part of the learning process developed under sub or no. 2. Through this exercise, the AER has developed a better understanding of the goals of the response plans, which were better defined through conversations with operators. Sub or no. 2 is consistent with the current state of the evolving science of induced seismicity and has the capacity to change as new information is obtained.
Spiritual Citizenship
Authors: Castor N. Fadeke 
Published: March 2018

In Spiritual Citizenship N. Fadeke Castor employs the titular concept to illuminate how Ifá/Orisha practices informed by Yoruba cosmology shape local, national, and transnational belonging in African diasporic communities in Trinidad and beyond. Drawing on almost two decades of fieldwork in Trinidad, Castor outlines how the political activism and social upheaval of the 1970s set the stage for African diasporic religions to enter mainstream Trinidadian society. She establishes how the postcolonial performance of Ifá/Orisha practices in Trinidad fosters a sense of belonging that invigorates its practitioners to work toward freedom, equality, and social justice. Demonstrating how spirituality is inextricable from the political project of black liberation, Castor illustrates the ways in which Ifá/Orisha beliefs and practices offer Trinidadians the means to strengthen belonging throughout the diaspora, access past generations, heal historical wounds, and envision a decolonial future.
The first transcriptomes from field-collected individual whiteflies (Bemisia tabaci, Hemiptera: Aleyrodidae): a case study of the endosymbiont composition
Authors: Sseruwagi Peter , Wainaina James , Ndunguru Joseph , Tumuhimbise Robooni , Tairo Fred , Guo Jian-Yang , Vrielink Alice , Blythe Amanda , Kinene Tonny , De Marchi Bruno , Kehoe Monica A. , Tanz Sandra , Boykin Laura M. 
Published: March 2018

Background: Bemisia tabaci species (B. tabaci), or whiteflies, are the world’s most devastating insect pests. They cause billions of dollars (US) of damage each year, and are leaving farmers in the developing world food insecure. Currently, all publically available transcriptome data for B. tabaci are generated from pooled samples, which can lead to high heterozygosity and skewed representation of the genetic diversity. The ability to extract enough RNA from a single whitefly has remained elusive due to their small size and technological limitations. Methods: In this study, we optimised a single whitefly RNA extraction procedure, and sequenced the transcriptome of four individual adult Sub-Saharan Africa 1 (SSA1) B. tabaci. Transcriptome sequencing resulted in 39-42 million raw reads. De novo assembly of trimmed reads yielded between 65,000-162,000 Contigs across B. tabaci transcriptomes. Results: Bayesian phylogenetic analysis of mitochondrion cytochrome I oxidase (mtCOI) grouped the four whiteflies within the SSA1 clade. BLASTn searches on the four transcriptomes identified five endosymbionts; the primary endosymbiont Portiera aleyrodidarum and four secondary endosymbionts: Arsenophonus, Wolbachia, Rickettsia, and Cardinium spp. that were predominant across all four SSA1 B. tabaci samples with prevalence levels of between 54.1 to 75%. Amino acid alignments of the NusG gene of P. aleyrodidarum for the SSA1 B. tabaci transcriptomes of samples WF2 and WF2b revealed an eleven amino acid residue deletion that was absent in samples WF1 and WF2a. Comparison of the protein structure of the NusG protein from P. aleyrodidarum in SSA1 with known NusG structures showed the deletion resulted in a shorter D loop. Conclusions: The use of field-collected specimens means time and money will be saved in future studies using single whitefly transcriptomes in monitoring vector and viral interactions. Our method is applicable to any small organism where RNA quantity has limited transcriptome studies.
The effect of triclosan-coated sutures on the rate of surgical site infection after hip and knee arthroplasty: a double-blind randomized controlled trial of 2546 patients
Authors: Sprowson† A. P. , Jensen C. , Parsons N. , Partington P. , Emmerson K. , Carluke I. , Asaad S. , Pratt R. , Muller S. , Ahmed I. , Reed M. R. 
Published: March 2018

Aims Surgical site infection (SSI) is a common complication of surgery with an incidence of about 1% in the United Kingdom. Sutures can lead to the development of a SSI, as micro-organisms can colonize the suture as it is implanted. Triclosan-coated sutures, being antimicrobical, were developed to reduce the rate of SSI. Our aim was to assess whether triclosan-coated sutures cause a reduction in SSIs following arthroplasty of the hip and knee. Patients and Methods This two-arm, parallel, double-blinded study involved 2546 patients undergoing elective total hip (THA) and total knee arthroplasty (TKA) at three hospitals. A total of 1323 were quasi-randomized to a standard suture group, and 1223 being quasi-randomized to the triclosan-coated suture group. The primary endpoint was the rate of SSI at 30 days postoperatively. Results The baseline characteristics of age, gender and comorbidities were well matched in the two groups. The rates of superficial SSI were 0.8% in the control group and 0.7% in the intervention group (p = 0.651), and when deep and superficial SSIs were combined the rates were 2.5% and 1.8 (p = 0.266). The length of stay in hospital and the rates of medical complications did not differ significantly between the groups (p = 1.000). Conclusion This trial provided no evidence that the use of triclosan-coated sutures at THA and TKA leads to a reduction in the rate of SSI. Cite this article: Bone Joint J 2018;100-B:296–302.