bluuebunny/crossref_metadata_2025_split huggingface dataset:
Balloon Test Occlusion for an Option to Decide Whether Simple ICA Ligation is Better Option than Trapping and High Flow Bypass of The Giant ICA Cavernous Aneurysm
Authors: Rajbhandari Saujanya , Rajbhandari Pravesh , Shrestha Pranaya , Pant Basant , Neupane Anish 
Published: May 2018

Balloon Test occlusion (BTO) is a preoperative angiographic test used to estimate the risk of stroke after permanent therapeutic occlusion of an internal carotid artery (ICA) involved by aneurysms. Temporary balloon occlusion at the cavernous ICA aneurysm neck was performed in an attempt to assess the adequacy of cross flow from the opposite ICA. Adequate fl ow following BTO are preferred to have simple ICA ligation and incase of those who did not pass BTO trapping and high flow bypass is preferred .We have done Right ICA Ligation on our case report.Nepal Journal of Neuroscience, Vol. 14, No. 2, 2017 Page:32-35
A Giant Solitary Solid Hemangioblastoma: A Case Report and Review of The Literature
Authors: Bhandari Rajeev , Sharma Gopal R , Bista Prakash , Jha Rajiv , Shrestha Rajendra , Poudel Prakash 
Published: May 2018

We present a case of solitary vascular tumor on posterior cranial fossa in a 15-year-old female who had a complaint of headache on/off for six months with associated dizziness, nausea, vomiting and vertigo. Well circumscribed solid vascular mass was localized on posterior fossa by computed tomography along with magnetic resonance imaging scan. Furthermore, the diagnosis was confirmed by surgical findings and histological examinations.Nepal Journal of Neuroscience, Vol. 14, No. 2, 2017 Page: 47-50
PENGGUNAAN TANAMAN AREN PADA UPACARA SIPAHA LIMA MASYARAKAT PARMALIM
Authors: Z.N.A Hanifah Mutia 
Published: May 2018

The purpose of this research are to know the beneficiaries and symbols contained in sugar palm plants in traditional ceremony Sipaha Lima. The method used in this research are the method of observation and depth interview. The data obtained in the form ofÂ plant parts used, how to obtain it and the meaning of symbol of the plant.The results is obtained eight types of use of sugar palm in traditional ceremony Sipaha Lima. Part of the plants used are: stems, leaves, and midrib. These plants are obtained from forests and crops.
PENGARUH KADAR ASAM SULFAT PADA HIDROLISIS TANDAN KOSONG KELAPA SAWIT (TKS) DAN WAKTU FERMENTASI TERHADAP KADAR BIOETANOL YANG DIHASILKAN
Authors: Sartini Sartini , Fitriani Rita , Lubis Rosliana 
Published: May 2018

The effect of sulphuric acid fermentation of processed palm oil bunch hydrolysis and on ethanol and sugar production was conducted. The aim was to investigate the hydrolytic optimum required by Saccharomyces cerevisiae for ethanol and sugar production. About 12.5 g powdered palm oil bunch was used in this experiment. The powder was hydrolized several times using sulphuric acid in several concentration. Sugar, product ofÂ hydrolysis, was detected every one hour using spectrophotometer. The sugar was fermented by Saccharomyces cerevisiae and incubated for several days. Results showed that 2-4% sulphuric acid was oprimum concentration for 30 g/L sugar production. The highest ethanol production 4.94% occurred after two days fermentation.
Pemasaran Politik Bupati Bima Terpilih Pada Pilkada Kabupaten Bima Tahun 2015
Authors: Nurfitriani Nurfitriani , Hamrun Hamrun , Taufik Ahmad 
Published: May 2018

<p>Pemasaran politik merupakan hal yang sangat penting dilakukan dalam suatu pemilihan karena dapat membantu efektifitas penyusunan produk politik, serta dapat menyampaikan produk politik tersebut secara luas kepada masyarakat. Pemasaran politik akan membawa manfaat baik itu bagi partai politik ataupun kandidat pasangan calon karena dengan adanya pemasaran politik hubungan mereka dengan pemilih akan terbangun dan secara tidak langsung dapat memberikan manfaat bagi masyarakat yang merupakan konsumen politik. Jenis penelitian ini adalah deskriptif kualitatif sehingga dapat menjelaskan obyek penelitian di kantor Bupati Bima dan kantor KPU Kabupaten Bima. Data dan informasi yang dibutuhkan dalam penelitian ini diperoleh dari informan. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah dengan melakukan observasi langsung dilokasi penelitian dan wawancara secara mendalam, dan dokumentasi. Data tersebut dianalisis melalui reduksi data yaitu merangkum dan fokus pada hal yang penting kemudian dilakukan penarikan kesimpulan.Hasil penelitian menunjukan bahwa pemasaran politik yang dilakukan oleh Bupati Bima terpilih belum efektif karena ada beberapa permasalahan yang di anggap sebagai faktor penghambat pada saat melakukan pemasaran politik.</p>
Open Innovation im Mittelstand
Authors: Stemplinger Christian T. , Voss Kimberly-Roxanne 
Published: May 2018

Kurzfassung
Der immer stärker werdende Innovationsdruck auf Unternehmen hat mittlerweile auch die kleinen und mittleren Unternehmen (KMU) erreicht und stellt diese vor neue Herausforderungen. Der vorliegende Beitrag zeigt anhand einer qualitativen Befragung, wie Betroffene und Experten die Chancen und Risiken dazu einschätzen. Eine anschließende Evaluation und Interpretation der Ergebnisse ermöglicht einen anwendungsorientierten Lösungsansatz für ein Open Innovation Konzept für die KMU inklusive eines Implementierungsleitfadens.
Durchgängige modellbasierte Bewertung von Regenerations-lieferketten
Authors: Lucht Torben , Schäfers Philipp , Nyhuis Peter 
Published: May 2018

Kurzfassung
Die Optimierung der Logistikleistung sowie der Logistikkosten sind zentrale Ziele der Regeneration komplexer Investitionsgüter. Aufgrund von Komplexität und interdependenten Wirkbeziehungen sind die Auswirkungen unterschiedlicher Konfigurationen von Regenerationslieferketten auf die logistischen Zielgrößen derzeit nicht prognostizierbar. Im Rahmen des SFB 871 wird am Institut für Fabrikanlagen und Logistik (IFA) daher ein Bewertungsmodell entwickelt, um die individuelle Gestaltung und Optimierung von Regenerationsprozessen für komplexe Investitionsgüter zu unterstützen.
Influence of the carbon content on the microstructure and properties of heat-resistant cast steels
Authors: Rongeat Carine 
Published: May 2018

Abstract
Two heat-resistant ferritic cast steels, 1.4476 and 1.4777 with a similar high Cr concentration, have been analyzed regarding their microstructures, mechanical properties, corrosion resistance and aging behavior. The differences observed between the grades are related to their different C contents. A higher C concentration ensures a higher mechanical resistance, in particular at high temperature (850°C) and also a better high-temperature (850°C) corrosion resistance. This is related to the formation of numerous carbides. However, this study also reveals that the microstructure of these steels is greatly affected by aging. In particular, the precipitation of the sigma phase and the formation of nitride precipitates could lead to failure during service at high temperature.
Dissimilar TIG Welding of HSLA to Austenitic High-Mn TRIP Steels
Authors: Buzolin R. H. , Rodrigues J. A. , Da Silva E. Pereira , Maluf O. , Pinto H. Cavalcanti 
Published: May 2018

Abstract
The microstructure and mechanical properties of dissimilar butt-joints of high-strength low-alloy steel to austenitic high Mn TRIP steels produced by manual TIG welding with AISI 309L filler metal were investigated. The heat input was varied by changing the welding current between 40 and 70 A. A fully austenitic microstructure with nearly equiaxed grains and without any iron/manganese carbide is observed in the high Mn TRIP base metal, whereas polygonal ferrite and pearlite colonies oriented along the rolling direction are found in the high-strength low-alloy steel base metal. Coarse and refined heat-affected zones (HAZ) were observed in the high-strength low-alloy steel, whereas no significant HAZ was detected at the TRIP side. Bainite and/or martensite grew in the coarse HAZ of the high-strength low-alloy steel steel joined with highest current. The weld seam was formed by austenitic dendrites with interdendritic ferrite and martensite. The best welding condition was achieved with an intermediate current of 50 A, where the hardness transition was smooth, fracture occurred in the HSLA base metal and the joint ductility was higher.
The Average Hazard Ratio – A Good Effect Measure for Time-to-event Endpoints when the Proportional Hazard Assumption is Violated?
Authors: Brannath Werner , Brückner Matthias , Kieser Meinhard , Rauch Geraldine 
Published: May 2018

Summary
Background: In many clinical trial applications, the endpoint of interest corresponds to a time-to-event endpoint. In this case, group differences are usually expressed by the hazard ratio. Group differences are commonly assessed by the logrank test, which is optimal under the proportional hazard assumption. However, there are many situations in which this assumption is violated. Especially in applications were a full population and several subgroups or a composite time-to-first-event endpoint and several components are considered, the proportional hazard assumption usually does not simultaneously hold true for all test problems under investigation. As an alternative effect measure, Kalbfleisch and Prentice proposed the so-called ‘average hazard ratio’. The average hazard ratio is based on a flexible weighting function to modify the influence of time and has a meaningful interpretation even in the case of non-proportional hazards. Despite this favorable property, it is hardly ever used in practice, whereas the standard hazard ratio is commonly reported in clinical trials regardless of whether the proportional hazard assumption holds true or not.
Objectives: There exist two main approaches to construct corresponding estimators and tests for the average hazard ratio where the first relies on weighted Cox regression and the second on a simple plug-in estimator. The aim of this work is to give a systematic comparison of these two approaches and the standard logrank test for different time-toevent settings with proportional and nonproportional hazards and to illustrate the pros and cons in application.
Methods: We conduct a systematic comparative study based on Monte-Carlo simulations and by a real clinical trial example.
Results: Our results suggest that the properties of the average hazard ratio depend on the underlying weighting function. The two approaches to construct estimators and related tests show very similar performance for adequately chosen weights. In general, the average hazard ratio defines a more valid effect measure than the standard hazard ratio under non-proportional hazards and the corresponding tests provide a power advantage over the common logrank test.
Conclusions: As non-proportional hazards are often met in clinical practice and the average hazard ratio tests often outperform the common logrank test, this approach should be used more routinely in applications.
Analysis of Instantaneous Linear, Nonlinear and Complex Cardiovascular Dynamics from Videophotoplethysmography
Authors: Iozzia Luca , Cerina Luca , Mainardi Luca , Barbieri Riccardo , Valenza Gaetano 
Published: May 2018

Summary
Background: There is a fast growing interest in the use of non-contact devices for health and performance assessment in humans. In particular, the use of non-contact videophotoplethysmography (vPPG) has been recently demonstrated as a feasible way to extract cardiovascular information. Nevertheless, proper validation of vPPG-derived heartbeat dynamics is still missing.
Objective: We aim to an in-depth validation of time-varying, linear and nonlinear/complex dynamics of the pulse rate variability extracted from vPPG.
Methods: We apply inhomogeneous pointprocess nonlinear models to assess instantaneous measures defined in the time, frequency, and bispectral domains as estimated through vPPG and standard ECG. Instantaneous complexity measures, such as the instantaneous Lyapunov exponents and the recently defined inhomogeneous point-process approximate and sample entropy, were estimated as well. Video recordings were processed using our recently proposed method based on zerophase principal component analysis. Experimental data were gathered from 60 young healthy subjects (age: 24±3 years) undergoing postural changes (rest-to-stand maneuver).
Results: Group averaged results show that there is an overall agreement between linear and nonlinear/complexity indices computed from ECG and vPPG during resting state conditions. However, important differences are found, particularly in the bispectral and complexity domains, in recordings where the subjects has been instructed to stand up.
Conclusions: Although significant differences exist between cardiovascular estimates from vPPG and ECG, it is very promising that instantaneous sympathovagal changes, as well as time-varying complex dynamics, were correctly identified, especially during resting state. In addition to a further improvement of the video signal quality, more research is advocated towards a more precise estimation of cardiovascular dynamics by a comprehensive nonlinear/complex paradigm specifically tailored to the non-contact quantification.
Literatura e memória: uma proposta de letramento literário para o conto popular no Ensino Fundamental
Authors: Munhoz Suriano Edivana Cássia , Corsi Margarida Da Silveira 
Published: May 2018

No segmento do Ensino Fundamental, a divulgação do repertório folclórico pode ocorrer por meio da literatura infanto-juvenil, uma vez que é importante que crianças e jovens entrem em contato com histórias, causos e lendas a que seus ascendentes tiveram acesso. Por isso, o presente trabalho tem o objetivo de resgatar a importância dos causos, ou seja, das narrativas orais contadas e recontadas de geração em geração, seu possível significado à época e sua ressignificação no contexto atual. Sendo uma das funções da escola a de valorizar e divulgar a cultura oral, um dos exemplares mais singulares é o conto popular. Assim, para contribuir com o resgate da memória e da história literária, escolhemos o (re)conto “Uma lição no fazendeiro”, do livro Causos de Pedro Malasartes, escrito por Júlio Emílio Braz e ilustrado por Anelise Zimmermann, para desenvolver uma proposta de letramento literário no ensino fundamental II. A fundamentação teórica deste trabalho baseou-se em Zilberman e Silva (1990), Silva (2009), Michelletti (2000), Cosson (2014) e Corsi (2015).
Optimizing NCLEX-RN Pass Rate Performance Using an Educational Microsystems Improvement Approach
Authors: Oliver Brant J. , Pomerleau Mimi , Potter Mertie , Phillips Andrew , Carpenter Susan , Ciesielski Steve , Pusey-Reid Eleanor , Marcous Alexia , Grobecker Pat 
Published: May 2018

Background:
Improvement methods were applied to optimize NCLEX-RN first-attempt pass rates in an Accelerated Bachelor of Science in Nursing (ABSN) program.

Method:
An improvement team was formed comprising nursing faculty, a student, faculty leading a course in the ABSN program involved in preparing students for NCLEX-RN, and a faculty expert in improvement science. Two Plan-Do-Study-Act (PDSA) cycles aimed at increasing practice and mastery were conducted. Effects were assessed using inferential statistics and statistical process control analyses.

Results:

One hundred eighty-four ABSN students participated over two semesters. Average practice questions per student per semester increased from 1,000 questions at baseline to 2,130 questions (
p
< .01) postintervention, average practice examinations from 2.9 to 3.2 (
p
< .05), and average practice test mastery from 6.8 to 7.2 on an 8-point scale (
p
< .05). First-attempt NCLEX-RN pass rates increased from 76.7% to 86.2% (
p
< .05).

Conclusion:

ABSN NCLEX-RN performance improved subsequent to this microsystem-based improvement effort. [
J Nurs Educ.
2018;57(5):265–274.]
Nursing Students' Perceptions of Safety and Communication Issues in the Clinical Setting
Authors: Gropelli Theresa , Shanty Joyce A. 
Published: May 2018

Background:
The purpose of this study is to describe nursing students' perceptions of safety issues and communication in clinical settings.

Method:
A descriptive study of nursing students' perceptions of safety and communication in clinical settings was conducted at a state university in the northeastern United States. Study participants consisted of 196 junior- and senior-level undergraduate nursing students in a baccalaureate program.

Results:
One third of the students reported thinking that mistakes are held against them. In addition, they reported fear of communicating an error and fear of asking questions if something does not seem right. The majority reported they never encountered a near-miss event and would not report an error that and not harm the patient. Students also responded that actual errors and near misses are not consistently reported.

Conclusion:

Findings indicate educators have an opportunity to enhance nursing curricula with strategies to foster and embrace a culture of safety. [
J Nurs Educ.
2018;57(5):287–290.]
Cost-Effective Virtual Clinical Site Visits for Nurse Practitioner Students
Authors: Alton Suzanne , Luke Sheba A. , Wilder Maureen 
Published: May 2018

Background:

Clinical site visits (CSVs) are critical to assess the progress of nurse practitioner (NP) students. To overcome the challenges of effectively assessing long-distance students while maintaining a reasonable faculty workload, faculty implemented a project using FaceTime
®
to conduct online CSVs to assess NP student progress. FaceTime is a videoconferencing program available on Apple
®
devices.

Method:

Site visits were conducted by school of nursing faculty with real-time observation of the NP student–patient encounter. Afterward, faculty then completed the student, site, and preceptor evaluations. Faculty, preceptors, and students were surveyed regarding ease of use and acceptability of the iPad
®
visits.

Results:
FaceTime CSVs provided faculty with the information needed to fill out the required evaluation forms of the student, preceptor, and site, and the iPad visits were easy to use and acceptable to all stakeholders.

Conclusion:

Using FaceTime for CSVs saved faculty travel time and used fewer program resources. [
J Nurs Educ.
2018;57(5):308–311.]
Poetry: An Innovative Teaching Strategy for Exploring Empathy With Beginning Nursing Students
Authors: Mood Laura 
Published: May 2018

Background:
Empathy is a professional value difficult to teach and challenging for beginning nursing students to grasp. This article describes how a poem was integrated in a seminar to engage students in exploring empathy and its relevance to their forming professional identities.

Method:

Preseminar, nursing students (
N
= 8) read a book chapter about thinking empathetically. In seminar, they read an assigned poem and, using guiding questions, discussed it in small and large groups. Postseminar, students wrote self-reflections about their most important learning of the week.

Results:
Through in-seminar discussions and postseminar reflections, students crafted new meanings of empathy, contemplated new insights, and integrated them into their imagined professional identities. In written self-reflections, six of eight students indicated the seminar was their most important learning of the week.

Conclusion:

Poetry is an engaging platform that makes accessible to beginning students the values of the profession that are difficult to articulate and grasp. [
J Nurs Educ.
2018;57(5):315–318.]
Midge (Diptera: Cecidomyiidae) injury to Brassicaceae in field trials in northeastern Saskatchewan, Canada
Authors: Andreassen Lars , Soroka Juliana , Grenkow Larry , Olfert Owen , Hallett Rebecca H. 
Published: May 2018

AbstractTo determine resistance of Brassicaceae field crops to Contarinia Róndani (Diptera: Cecidomyiidae) midge complex (Contarinia nasturtii Kieffer and Contarinia undescribed species), field trials of two different host assemblages were undertaken near Melfort, Saskatchewan, Canada in 2014 and repeated in 2015. In both years the first midge adults appeared in early July, when most plants were starting to flower, and a second generation occurred in mid-August, past the period of crop susceptibility. In a trial studying 18 lines of six brassicaceous species, the lowest probability of midge injury was found on Camelina sativa (Linnaeus) Crantz lines in both years. No differences were found in the probability of midge injury among any of the 13 Brassica Linnaeus species lines tested, including commercial glyphosate-resistant and glufosinate-resistant Brassica napus Linnaeus canola lines, Ethiopian mustard (Brassica carinata Braun), brown or oriental mustard (Brassica juncea (Linnaeus) Czernajew), or Polish canola (Brassica rapa Linnaeus) lines. Probability of midge injury on Sinapis alba Linnaeus yellow mustard lines reached levels between those on Camelina sativa lines and those on Brassica lines. A second trial examining 14 current commercial glyphosate-resistant Brassica napus canola cultivars found no differences in susceptibility to midge feeding among any cultivars tested. More plants were damaged in 2015 in both studies, and damage reached maximum levels earlier in 2015 than in 2014.
Canonical TGF-β Signaling Pathway Represses Human NK Cell Metabolism
Authors: Zaiatz-Bittencourt Vanessa , Finlay David K. , Gardiner Clair M. 
Published: May 2018

Abstract
Cytokines stimulate rapid metabolic changes in human NK cells, including increases in both glycolysis and oxidative phosphorylation pathways. However, how these are subsequently regulated is not known. In this study, we demonstrate that TGF-β can inhibit many of these metabolic changes, including oxidative phosphorylation, glycolytic capacity, and respiratory capacity. TGF-β also inhibited cytokine-induced expression of the transferrin nutrient receptor CD71. In contrast to a recent report on murine NK cells, TGF-β–mediated suppression of these metabolic responses did not involve the inhibition of the metabolic regulator mTORC1. Inhibition of the canonical TGF-β signaling pathway was able to restore almost all metabolic and functional responses that were inhibited by TGF-β. These data suggest that pharmacological inhibition of TGF-β could provide a metabolic advantage to NK cells that is likely to result in improved functional responses. This has important implications for NK cell–based cancer immunotherapies.
IL-2 Enhances Gut Homing Potential of Human Naive Regulatory T Cells Early in Life
Authors: Hsu Peter S. , Lai Catherine L. , Hu Mingjing , Santner-Nanan Brigitte , Dahlstrom Jane E. , Lee Cheng Hiang , Ajmal Ayesha , Bullman Amanda , Arbuckle Susan , Al Saedi Ahmed , Gacis Lou , Nambiar Reta , Williams Andrew , Wong Melanie , Campbell Dianne E. , Nanan Ralph 
Published: May 2018

Abstract
Recent evidence suggests early environmental factors are important for gut immune tolerance. Although the role of regulatory T (Treg) cells for gut immune homeostasis is well established, the development and tissue homing characteristics of Treg cells in children have not been studied in detail. In this article, we studied the development and homing characteristics of human peripheral blood Treg cell subsets and potential mechanisms inducing homing molecule expression in healthy children. We found contrasting patterns of circulating Treg cell gut and skin tropism, with abundant β7 integrin+ Treg cells at birth and increasing cutaneous lymphocyte Ag (CLA+) Treg cells later in life. β7 integrin+ Treg cells were predominantly naive, suggesting acquisition of Treg cell gut tropism early in development. In vitro, IL-7 enhanced gut homing but reduced skin homing molecule expression in conventional T cells, whereas IL-2 induced a similar effect only in Treg cells. This effect was more pronounced in cord compared with adult blood. Our results suggest that early in life, naive Treg cells may be driven for gut tropism by their increased sensitivity to IL-2–induced β7 integrin upregulation, implicating a potential role of IL-2 in gut immune tolerance during this critical period of development.