bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adverse cardiological and neurological reactions associated with air traffic and the possibility of their pharmacological correction
Authors: Trukhan D. I. , Ivanova D. S. 
Published: November 2024

Air transport may provoke or aggravate a medical event in a passenger with concomitant medical problems. We searched the PubMed and Scopus databases for the period up to 08/29/2024 for sources that examined the impact of air travel on human health. There are 2 main categories of stressors associated with air travel and affecting the body, generally divided into:(1) psychological and physical stressors and (2) physiological Possible changes in health associated with air travel can be divided into functional, mostly reversible, and organic: (1) exacerbation/decompensation of existing somatic pathology;(2) development of pathological conditions de novo, for which possible stressors can serve as a trigger, directly or sequentially as a result of the previous development and progression of functional disorders. The literature focuses on safety issues during air travel for patients with existing cardiovascular pathology. Adverse functional cardiological and neurological reactions and their pharmacological correction have been less studied. Fear of flying and phobia of flying are very common among the general population and can lead to significant stress. For situational correction of reactions to everyday stressful events, it is possible to use drugs with anxiolytic action of a non-benzodiazepine This group includes the drug Valocordin®, the action of which is aimed at various manifestations of stress, anxiety states, autonomic dysfunction, increased excitability and irritability, mild sleep disorders. In case of pre-flight anxiety and fear, taking Valocordin® (depending on the situation or in a short course) can be the drug of choice for both the air traveler and his relatives seeing him off/meeting him.
Idiopathic pulmonary hypertension in an adult with patent foramen ovale
Authors: Shumilin A. A. , Pavlov A. I. , Prokhorchik A. A. , Cherniaev A. L. , Samsonova M. V. , Slavetskya M. A. 
Published: November 2024

The article is devoted to the clinical case of combined idiopathic pulmonary hypertension with an open foramen ovale of the atrial septum in a young man of 21 years old with progressive decrease in lung ventilation function. The relationship of pulmonary arterial hypertension with an open foramen ovale of the atrial septum is nearly not described in the literature, as it is rarely found in clinical practice. According to the classification, pulmonary hypertension is divided into idiopathic (primary), secondary and pulmonary hypertension caused by other causes. In the pathogenesis of any PAH, an important role belongs to a complex of vascular changes. Verification of vascular changes is carried out histologically. Variants of idiopathic pulmonary hypertension are plexiform and thrombotic arteriopathy, veno-occlusive disease, capillary hemangiomatosis. An open foramen ovale as a structural anomaly of the adult heart (a vestige of embryonic blood circulation) causes a variety of hemodynamic disorders that can affect the pathogenesis of pulmonary hypertension. Because of this, preclinical observation of a combination of plexiform and thrombotic arteriopathy with a patent foramen ovale of the interatrial septum in a young man of 21 years old and an attempt to determine the role of an open oval window in the progression of pulmonary hypertension and its effect on treatment is of interest. The diagnosis of idiopathic pulmonary hypertension was made based on the clinical picture, laboratory parameters, echocardiography and histological examination of pulmonary vessels. The article discusses the importance of a patent foramen ovale in the pathogenesis of idiopathic pulmonary hypertension.
Decreased vitamin D levels as a factor of deterioration of osseointegration during dental implantation
Authors: Ilovayskaya I. A. , Amkhadova M. A. , Kadiev A. A. , Amkhadov I. S. , Dzhabrailova М. A. 
Published: November 2024

Introduction. Decreased vitamin D levels are considered as a possible factor in dental implantation failure. However, there arelack of good quality studies on this topic, some of which were conducted on animal models.Aim. To identify the possible role of vitamin D levels on osseointegration parameters during dental implantation.Materials and methods. A retrospective single-sample cohort observational non-interventional study was conducted. 78 female patients who underwent dental implantation were examined, who were divided into 3 groups: up to 44 years old, group 1 (n = 20), 45-60 years old, group 2 (n = 34), 60 years and older, group 3 (n = 24). All patients were examined before implantation: vitamin D, FSH, estradiol, TSH, free T4, computed tomography of the jaw bones, indices of the gums and periodontium condition, also the implant stability quotient (ISQ) was determined at the time of implant placement and at the time of prosthetics.Results. The concentrations of vitamin D, estradiol, jaw bone density, and ISQ at the time of implantation and at the time of prosthetics were significantly lower in group 3. Vitamin D deficit/insufficiency occurred in 38%, 58%, 88% of patients in groups 1, 2, 3, respectively (p < 0.001). The ratio of chances to detect a decrease in vitamin D was 13.1 (CI 95% 2.9–60.2) in group 3 compared to group 2, and 5.7 (CI 95% 1.4–22.6) compared to group 1. The ratio of the chances for an increase of osseointegration time was 11.6 (CI 95% 2.3–59.1) in case of vitamin D deficiency compared to optimal values, and 5.7 (CI 95% 1.4–24.1) compared to a insufficiency condition. Vitamin D levels significantly inversely correlated with hygienic indices of periodontal condition.Conclusion. A decrease vitamin D levels can be strongly considered as a factor in the deterioration of osseointegration during dental implantation, since this is associated with an extended period of osseointegration due to a decrease in the bone density of the jaw and a worse periodontal condition.
Water quality estimates using machine learning techniques in an experimental watershed
Authors: Costa David , Bayissa Yared , Barbosa Kargean Vianna , Villas-Boas Mariana Dias , Bawa Arun , Junior Jader Lugon , Neto Antônio J. Silva , Srinivasan Raghavan 
Published: November 2024

ABSTRACT

This study aims to identify the best machine learning (ML) approach to predict concentrations of biochemical oxygen demand (BOD), nitrate, and phosphate. Four ML techniques including Decision tree, Random Forest, Gradient Boosting and XGBoost were compared to estimate the water quality parameters based on biophysical (i.e., population, basin area, river slope, water level, and stream flow), and physicochemical properties (i.e., conductivity, turbidity, pH, temperature, and dissolved oxygen) input parameters. The innovation lies in the combination of on-the-spot variables with additional characteristics of the watershed. The model performances were evaluated using coefficient of determination (R2), Nash-Sutcliffe efficiency coefficient (NSE), Root Mean Squared Error (RMSE) and Kling-Gupta Efficiency (KGE) coefficient. The robust five-fold cross-validation, along with hyperparameter tuning, achieved R2 values of 0.71, 0.66, and 0.69 for phosphate, nitrate, and BOD; NSE values of 0.67, 0.65, and 0.62, and KGE values of 0.64, 0.75, and 0.60, respectively. XGBoost yielded good results, showcasing superior performance when considering all analysis performed, but his performance was closely match by other algorithms. The overall modeling design and approach, which includes careful consideration of data preprocessing, dataset splitting, statistical evaluation metrics, feature analysis, and learning curve analysis, are just as important as algorithm selection.
A groundwater level spatiotemporal prediction model based on graph convolutional networks with a long short-term memory
Authors: Wang Lifang , Jiang Zhengwen , Song Lei , Yu Xi , Yuan Shujun , Zhang Baoyi 
Published: November 2024

ABSTRACT

The performance of regional groundwater level (GWL) prediction model hinges on understanding intricate spatiotemporal correlations among monitoring wells. In this study, a graph convolutional network (GCN) with a long short-term memory (LSTM) (GCN–LSTM) model is introduced for GWL prediction utilizing data from 16 wells located in the northeastern Xiangtan City, China. This model is designed to account for both the hybrid temporal dependencies and spatial autocorrelations among wells. It consists of two parts: the spatial part employs GCNs to extract spatial characteristics from a spatial self-similarity weight matrix and an attribute self-similarity weight matrix among wells; the temporal part utilizes a LSTM module to capture the temporal patterns of GWL sequences, along with monthly precipitation and temperature data. This model dynamically predicts changes in groundwater levels, achieving higher accuracy on average compared to single-well predictions using LSTM. By incorporating both temporal dependencies and spatial autocorrelations, the GCN–LSTM model demonstrated an average improvement in goodness-of-fit of approximately 11.21% over the LSTM-based model for individual wells. Its application holds significant reference value for the sustainable utilization and development of groundwater resources in Xiangtan City.
ENSINO DE BOAS PRÁTICAS DE ESCRITA DA PRESCRIÇÃO DE MEDICAMENTOS NA GRADUAÇÃO EM MEDICINA
Authors: Mariz Batista Almária , Da Silva Gama Zenewton André , Bezerra de Souza Dyego Leandro , De Oliveira Costa Raphael Raniere 
Published: November 2024

PROBLEMA: Prescrição é a etapa de maior prevalência de falhas evitáveis no processo de medicação, o que suscita a necessidade de ensino de boas práticas de escrita da prescrição de medicamentos. MÉTODO: Estudo descritivo da construção e aplicação de um método de ensino-aprendizagem de boas práticas de escrita da prescrição de medicamentos para estudantes de graduação em Medicina. O método, intitulado “Ensino de Boas Práticas de Escrita da Prescrição de Medicamentos”, consiste em 8 etapas. Foi desenvolvido por docentes da Universidade Federal do Rio Grande do Norte, Brasil. Tem como premissa os pressupostos da aprendizagem significativa, da aprendizagem baseada em pares e o instrumento QualiPresc, um instrumento validado para avaliar a qualidade da escrita da prescrição de medicamentos na atenção primária. RESULTADOS: Após o desenvolvimento, foi aplicado, na forma de piloto. As percepções preliminares sobre sua implementação apontam para um método de ensino-aprendizagem com potencial para sua implementação e disseminação em cursos de Medicina no Brasil, para a melhoria da qualidade e segurança do processo de medicação. CONCLUSÕES: Em virtude de seu caráter de “piloto”, mais estudos precisam ser desenvolvidos no sentido de aferir a efetividade do método em detrimento de outras estratégias de ensino e aprendizagem utilizadas para a mesma finalidade.
Factors Contributing to Formation and Existence of Community Identities in Bangkok Metropolis
Authors: Chitchakkol Nutdhapol , Rugwongwan Yanin , Pongsermpol Chotewit 
Published: November 2024

In Bangkok, some traditional communities have maintained their identity despite urbanization. This research investigates the factors that influence the formation and existence of identities in three historic communities: Sam Phraeng, Talat Noi, and Soi Prachanaruemit (Wood Street). The research uses surveys, observations, and interviews to examine tangible and intangible elements. The results indicate that community identity originates from tangible elements such as architecture and landmarks, including intangible elements such as economics and society. Participation is essential to maintaining these identities, which requires effective community management, leading to income generation through activities and tourism that reflect the existence of community identities.
Considering Comorbidities and Individual Differences in Testing a Gaming Behavioral Activation App for Perinatal Depression and Anxiety: Open Trial Pilot Intervention Study
Authors: Hamlett Gabriella E , Schrader Chloe , Ferguson Craig , Kobylski Lauren A , Picard Rosalind , Locascio Joseph J , McNally Richard J , Cohen Lee S , Vanderkruik Rachel 
Published: November 2024

Abstract

Background
There is increasing interest in the development of scalable digital mental health interventions for perinatal populations to increase accessibility. Mobile behavioral activation (BA) is efficacious for the treatment of perinatal depression; however, the effect of comorbid anxiety and depression (CAD) on symptom trajectories remains underexplored. This is important given that at least 10% of women in the perinatal period experience CAD.

Objective
We assessed whether there were differences in symptom trajectories in pregnant participants with CAD as compared to those with depression only (ie, major depressive disorder [MDD]) during intervention with a BA mobile gaming app.

Methods
Pregnant adults with either CAD (n=10) or MDD (n=7) used a BA app for 10 weeks and completed biweekly symptom severity questionnaires for depression and anxiety. We assessed whether baseline diagnoses were associated with differential symptom trajectories across the study with mixed effects longitudinal models.

Results
When controlling for baseline symptoms, results revealed a significant interaction between baseline diagnosis and the quadratic component of study week on anxiety (β=.18, SE 0.07; t62=2.61; P=.01), revealing a tendency for anxiety in the CAD group to increase initially and then decrease at an accelerated rate, whereas MDD symptoms were relatively stable across time. There was a significant effect of linear time on depression (β=−.39, SE 0.11; t68=−3.51; P=.001), showing that depression declined steadily across time for both groups. There was a significant effect of baseline diagnosis on depression (β=−8.53, SE 3.93; t13=−2.17; P=.05), suggesting that those with MDD had higher follow-up depression compared to those with CAD when holding other predictors constant.

Conclusions
The app was beneficial in reducing depression symptoms in perinatal individuals with different comorbidity profiles. With respect to anxiety symptom trajectories, however, there was more variability. The app may be especially effective for the treatment of anxiety symptoms among individuals with CAD, as it encourages in-the-moment ecologically relevant exposure to anxiety-provoking stimuli. Despite no significant group difference in baseline anxiety symptoms, the MDD group did not have a significant reduction in their anxiety symptoms across the study period, and some individuals had an increase in anxiety. Findings may point to opportunities for the augmentation of BA gaming apps for those with MDD to more effectively target anxiety symptoms. Overall, findings suggest there may be value in considering comorbidities and individual variations in participants when developing scalable mobile interventions for perinatal populations.
Modifikasi Pertumbuhan Bunga Matahari (<i>Helianthus annuus</i> L.) sebagai Tanaman Hias Pot dengan Aplikasi Paklobutrazol
Authors: Trisnaningtyas Carenina , Indradewa Didik , Purwantoro Aziz 
Published: November 2024

Paklobutrazol merupakan zat pengatur tumbuh yang berfungsi menghambat pertumbuhan vegetatif tanaman dan banyak digunakan untuk mengurangi tinggi tanaman khususnya pada tanaman hias pot. Tanaman hias pot memerlukan keragaan batang yang pendek sehingga penelitian ini bertujuan untuk mempelajari pengaruh aplikasi paklobutrazol terhadap pertumbuhan dan kualitas tanaman bunga matahari serta menentukan aplikasi paklobutrazol terbaik dalam menjadikan tanaman bunga matahari sebagai tanaman hias pot. Penelitian dilaksanakan pada bulan November 2021 – April 2022 di Kebun Kursus Pertanian Taman Tani, Kota Salatiga. Penelitian menggunakan Rancangan Faktorial 3 x 3 + 1 yang diatur dalam Rancangan Acak Kelompok Lengkap dengan tiga blok sebagai ulangan. Faktor pertama adalah konsentrasi paklobutrazol dengan 3 aras yaitu 100 ppm, 200 ppm, dan 300 ppm. Faktor kedua adalah frekuensi aplikasi paklobutrazol dengan 3 aras yaitu 4 kali (selang aplikasi 14 hari sekali), 5 kali (selang aplikasi 10 hari sekali) dan 6 kali (selang aplikasi 7 hari sekali). Aplikasi paklobutrazol dilakukan dengan cara penyiraman langsung pada media tanam selama fase vegetatif tanaman yaitu 2 – 8 mst. Data yang diperoleh diuji menggunakan analisis varian faktorial dan kontras orthogonal. Apabila hasil berbeda nyata dilakukan uji lanjut dengan uji HSD-Tukey α5%. Hasil penelitian menunjukkan bahwa aplikasi paklobutrazol menghambat pertumbuhan vegetatif dan proses pembungaan tanaman yang menghasilkan tanaman bunga matahari pot dengan keragaan tanaman pendek, berbunga tunggal, berukuran sedang, berwarna kuning cerah kontras dengan daun yang berwarna hijau gelap yang berukuran kecil dan tersusun rapat. Aplikasi paklobutrazol konsentrasi 300 ppm dengan frekuensi 4 kali (selang aplikasi 14 hari sekali) mampu menjadikan bunga matahari sebagai tanaman pot dengan tinggi dan diameter bunga terbaik sesuai kriteria tanaman pot varietas acuan.
Deteriorasi Benih pada 25 Sumber Tetua Padi Tahan Tungro
Authors: Firmansyah Firmansyah , Ismayanti Rini , Ibrahim Elisurya , Muis Asmary , Komalasari Ema 
Published: November 2024

Ketersediaan sumber benih sebagai tetua bahan persilangan padi tahan tungro perlu diperhatikan sebagai salah satu aspek dalam merakit varietas tahan tungro. Kondisi ruang penyimpanan yang tidak tepat dapat menyebabkan terjadinya deteriorasi selama masa penyimpanan benih. Penelitian ini bertujuan untuk melihat kemampuan simpan benih 25 varietas padi sumber tetua persilangan selama masa penyimpanan satu tahun. Penelitian ini disusun menggunakan Rancangan Acak Lengkap diulang empat kali, Apabila berbeda nyata dilakukan Uji DMRT dan dilakukan pengelompokan menggunakan PCA Biplot. Pengukuran sampel mengikuti standar ISTA. Hasil menunjukkan sebanyak 16 varietas mengalami deteriorasi namun varietas Cigeulis, Towuti, Situpatenggang dan Inpari 40 memiliki potensi tumbuh maksimal terbaik dengan kadar air dibawah 13 % sesuai dengan standar ISTA selama masa penyimpanan satu tahun. Kelompok varietas dengan potensi tumbuh terbaik yaitu Varietas Cigeulis, Towoti, Situ Patenggang, Inpari 40, Tukad Petanu, Ciherang, Tukad Balian, Bondoyudo dan Mekongga. Adapun Varietas Cibogo, Mekongga dan Inpara 7 berkelompok memiliki Bobot 1000 biji yang tinggi. Potensi tumbuh maksimum sangat nyata dan berkorelasi positif dengan Bobot 1000 biji, namun menunjukkan kecenderungan pola hubungan yang negatif pada kadar air benih. Kadar air dan bobot 1000 biji memiliki korelasi lemah dengan pola hubungan negatif.
Pengaruh Pemberian Biochar Sekam Padi - Kotoran Ayam untuk Pertumbuhan dan Produksi Tomat di Lahan Gambut
Authors: Indrawati Urai Yulies , Al-Haddad Abdul Mujib 
Published: November 2024

Budidaya tanaman tomat pada tanah gambut memiliki beberapa kendala, terutama karena tingkat kesuburan tanah gambut yang kurang baik, seperti rendahnya pH tanah (<4), rendahnya N,P,K, kapasitas pertukaran kation tinggi namun kejenuhan basa yang rendah akibat tingginya asam-asam organik. Untuk mengatasi kendala tersebut, tanah gambut perlu amelioran yang mudah didapat dan murah harganya, selain pemberian pupuk N, P dan K, yaitu dengan pemberian biochar sekam padi dan biochar kotoran ayam. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian kombinasi biochar sekam padi dan biochar kotoran ayam terhadap ketersedian hara N, P, K, pertumbuhan dan hasil tanaman tomat di tanah gambut. Desain penelitian menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari dosis kombinasi biochar sekam padi kotoran ayam B0 = Tanpa perlakuan biochar, tetapi tetap diberikan NPK, B1= 15 t ha-1, B2 = 30 t ha-1, B3 = 45 t ha-1 dan B4 = 60t.ha-1. Hasil penelitian menunjukkan bahwa pemberian biochar sekam padi dan biochar kotoran ayam berpengaruh nyata terhadap semua parameter. Perlakuan biochar sekam padi-kotoran ayam pada perlakuan B4 (1.660 g) meningkatkan produksi tomat mencapai 331%, Serapan N 482 %, Serapan P 141 %, Serapan K 128 % dibanding kontrol.
Keragaman Mangga (<i>Mangifera indica</i> L.) di Jawa Timur Berdasarkan Karakter Morfologi: Studi Kasus di Kabupaten Jember
Authors: Sari Vega Kartika , Sa'diyah Halimatus , Rusdiana Riza Yuli , Hariyono Kacung , Hartatik Sri 
Published: November 2024

Di Indonesia, mangga terdistribusi luas dan memiliki keragaman bentuk, ukuran, rasa dan bentuk daun. Jawa Timur termasuk sentra produksi mangga dengan produksi mencapai 41% dari produksi nasional. Beragam jenis mangga dapat tumbuh baik di Kabupaten Jember. Mangga lokal yang ada perlu dikarakterisasi terutama yang memiliki keunggulan untuk dapat dikembangkan sebagai buah unggulan daerah. Penelitian ini bertujuan untuk mengkarakterisasi morfologi berbagai jenis mangga dari delapan kecamatan di Kabupaten Jember. Pengambilan sampel dilakukan secara purposive sampling. Data pengamatan dianalisis deskriptif, korelasi, biplot, dan klaster. Hasil eksplorasi diperoleh 12 jenis mangga terdiri atas mangga lokal seperti apel hijau, apel merah, padi, cantel, mahatir, telur, madura selain gadung, manalagi, arum manis, golek, dan kweni. Hasil analisis menunjukkan koefisien variasi yang tinggi pada karakter panjang tangkai daun dan panjang tangkai bunga. Dua karakter tersebut juga berkorelasi sangat signifikan dan positif, demikian pula karakter panjang dan lebar buah terhadap bobot buah. Panjang helai daun dapat digunakan dalam menentukan karakter penciri morfologi daun mangga. Jenis mangga Cantel memiliki keunikan dengan tingkat ketidakmiripan 43,5% dibandingkan 11 jenis mangga lainnya. Pengelompokan jenis mangga yang terbentuk berdasarkan kemiripan/ketidakmiripan karakter morfologi meskipun berasal dari lokasi yang berbeda
Cambrian oncolites from San José de Gracia, Sonora, Mexico
Authors: Beraldi-Campesi Hugo , Cuen-Romero Francisco , Buitrón-Sánchez Blanca E. 
Published: November 2024

Recently discovered oncolites from a Lower Cambrian locality in San José de Gracia (SJG), Sonora (Mexico), illustrate the wide geographic distribution that they had in this part of Laurentia some 515–510 Ma ago. They are exceptionally large (~44 mm) in comparison to other marine forms of the North American Cambrian Carbonate Bank, but similar in their overall morphology and depositional environment. Their association with abundant biomorphs, especially indigenous filamentous structures with the curvature and spatial arrangement that fit the minimum criteria for biogenicity, supports their biological origin. Key morphological features include laminated growth in at least a portion of the oncolite, subspherical shape with internal porosity, and a nucleated habit on skeletal debris (mollusk shells) and mud concretions. The similarity of SJG oncolites with others from Cambrian outcrops separated today by hundreds of kilometers, suggests that massive microbially-driven, shallow marine ecosystems existed in western Laurentia during this time. This speaks of the impact that microbes had in shaping marine sediments, and the global primary productivity and carbon cycle during early stages of the Phanerozoic.