bluuebunny/crossref_metadata_2025_split huggingface dataset:
Significant role and the underly mechanism of cullin-1 in chronic obstructive pulmonary disease
Authors: Hao Wenbo , Lin Fei , Kong Weili , Shi Hanbing , Dong Haiying , Guan Zhanjiang , Liu Guohua , Wang Xiao , Wang Li , Liu Moran , Jiang Yunfei 
Published: November 2024

Abstract

Background
This study investigated the role and mechanisms of cullin-1 (CUL1) in chronic obstructive pulmonary disease (COPD).

Methods
Cigarette smoke extract (CSE)-treated mouse pulmonary microvascular endothelial cells (mPMECs) and cigarette smoke inhalation (CSI)-stimulated mice were used to construct in vitro and in vivo COPD models, respectively. CUL1 expression was assessed using reverse transcriptase-quantitative polymerase chain reaction, Western blotting, and immunohistochemistry. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and flow cytometry were used to detect cell viability and apoptosis, respectively. We conducted an enzyme-linked immunosorbent assay on mPMECs and bronchoalveolar lavage fluid (BALF) to detect inflammatory factors. Reactive oxygen species, malondialdehyde, and superoxide dismutase were detected using the corresponding kits. The histological characteristics of the lung tissues were determined by hematoxylin and eosin staining.

Results
CUL1 expression was downregulated in COPD. CUL1 overexpression significantly promoted cell viability, reduced cell apoptosis, and inhibited inflammatory responses and oxidative stress in CSE-treated mPMECs. These changes were reversed by the p53 agonist nutlin-3. In addition, CUL1 overexpression significantly relieved COPD in mice, as confirmed by the reduced secretion of inflammatory factors in BALF, inhibited oxidative stress response, and improved lung function.

Conclusion
CUL1 plays a protective role in CSE-treated mPMECs and CSI-stimulated mice by inhibiting the p53 signaling pathway.
Impact of the manufacturing process on the quality of welds in twin wire mesh fencing
Authors: Schulz I. , Katrakova-Krüger D. , Weichert S. , Aydin M. 
Published: November 2024

Abstract
The aim of this study is to demonstrate differences in the manufacturing of twin wire mesh panels for fencing systems. To this end, twin wire mesh panels made of S235JR and of identical and different dimensions were received from different manufacturers for comparison and in order to reveal differences resulting from the manufacturing process. The quality of the panels was evaluated using light optical microscopy, Vickers hardness tests, scanning electron microscopy as well as tensile tests. Differences in the structure of the weld will be demonstrated by means of metallographic sections and hardness profiles. The zinc coatings deposited by different processes for corrosion protection were characterized by coating thickness measurements on cross sections, light optical microscopy and energy dispersive X-ray spectroscopy (EDS) measurements. Tensile tests using a specially developed clamping device were performed in order to draw conclusions on the durability of the welds.
Aspects of pitch in textsetting: a suprasegmental analysis of two Turkish versions of Franz Schubert’s Ellens Gesang III (D. 839)
Authors: Güven Mine 
Published: November 2024

Abstract
Focusing on the interaction of linguistic stress with the poetic and musical meters, and the melodic contour, this paper provides a qualitative suprasegmental analysis of two Turkish versions (T1: Ah! Güzel yavrum; T2: Duy ey sevgili sesimi!) of Franz Schubert’s Ellens Gesang III (D. 839). The acceptability of Turkish lyrics despite the failure of T1/T2 to align stressed syllables with strong positions in the iambic feet points towards the relative insignificance of poetic meter. Based on an analysis of the 36 downbeats, alignment rates (the second German version [95.8 %] > the original German version [91.7 %] > T2 [66.7 %] > T1 [50 %]) suggest that factors such as word length and default final stress may have proven counter-productive for Turkish in stress-meter alignment. As long as musical phrasing is in conformity with linguistic phrasing, a melodic contour that mirrors phrasal/sentential intonation may reinforce intended meaning despite mismatched syllables. Singable lyrics need not exhibit absolute stress-peak alignment such that various degrees of mismatches may be tolerable, depending on factors such as melismatic versus syllabic notation, the relative duration of adjacent syllables, and whether or not the mismatch occurs at tactus level.
Musiktherapeutisches Verstehen auf Basis psychoanalytischer Theorie
Authors: Baier Christoph 
Published: November 2024

Zusammenfassung
Der Artikel versucht, einen Deutungsrahmen für musiktherapeutisches Geschehen auf Basis psychoanalytischer Ansätze zu entwickeln. Er folgt der These, dass musikalisches Geschehen psychische Strukturen in ihrer Bezogenheit abbildet. Im Laufe des Textes wird dies unter dem Aspekt der innerpsychischen und kollektivpsychischen Dimension ausdifferenziert, in der Annahme, dass individuelle psychische Entwicklung aus einer kollektiv archetypischen Dimension erwächst. Musikalisches Schaffen ist so einerseits differenzierte Kulturpraxis, bildet gleichzeitig jedoch therapeutisch relevante präverbale Beziehungsmodi ab. In der praktischen therapeutischen Arbeit ist es notwendig, diese richtig einordnen zu können, um einen innerpsychischen Symbolisierungsprozess der Patientin oder des Patienten zu unterstützen und zu gewährleisten.
Collective Property in the Modern State: Émile de Laveleye’s
Primitive Property
in its Global Context
Authors: Török Borbála Zsuzsanna 
Published: November 2024

Abstract
The article discusses normative approaches to the commons and argues that similar perspectives emerged in the late nineteenth century, closely linked to claims of social and ecological justice. It posits its subject in the framework of nineteenth-century territorialization, more precisely the exercise of state power as a convergence of normative representations of the space and legislative and administrative practices. Analyzing the theoretical and political dimensions of a representative scholarly work, titled De la propriété et de ses forms primitives by the Belgian professor Émile de Laveleye (1822–1892), it formulates the thesis that Laveleye’s book is indicative of the renegotiation of the status of collective property in land as state territory. The article shows first how the book was shaping a universalist model of common land ownership by waving together European and colonial debates on the topic. Second, by following the English and German translations of the book, it shows how this model was linked to transnational agendas of social politics and land reform. These two aspects draw attention to the crucial role of the state as a historical and present stakeholder in shaping the status of commons as territories.
A metafísica na Crítica da Razão Pura
Authors: De Queiroz Carneiro Gonçalves Mailson Bruno 
Published: November 2024

Kant inicia a Crítica da Razão Pura destacando, no prefácio de 1781, o problema imanente à faculdade racional: o conhecimento. Embora o autor reconheça no homem o desejo pela descoberta de princípios gerais, proveniente do interrogatório que lhe é inevitável, essa busca está condenada a desfechos inconclusivos quando seu objeto ultrapassa as condições de possibilidade gnosiológica. O sujeito cognoscente, baseados em pressupostos legados historicamente como eternos e necessários, pretende responder a pluralidade de questões que lhe é imposta pela razão, mas a arbitrariedade de leis gerais transforma sua tarefa num ritual tirânico e obscuro.
Arché (ἀρχή) na filosofia de Hannah Arendt: As modalidades da vita activa e o privilégio da ação
Authors: DA SILVA DOS SANTOS LANA HELENA 
Published: November 2024

ResumoHannah Arendt ao propor a reabilitação da vita activa, busca salientar o privilégio da ação sobre as outras atividades da condição humana. Ao analisar a mudança de significado da palavra “arché'', a filósofa prioriza o nascimento, que têm em seu sentido mais puro, o iniciar. Nesse contexto, este trabalho pretende desenvolver a importância da Arché na reabilitação da "atividade política por excelência ", ou seja , a ação. Palavras chaves : vita activa, ação, arché, política, condição humana.Abstract Hannah Arendt, in proposing the rehabilitation of active life, seeks to highlight the privilege of action on other activities of the human condition. When analyzing the change in meaning of the word “arché '”, the philosopher prioritizes birth, which in its purest sense, begins it. In this context, this work intends to develop the importance of Arché in the rehabilitation of "political activity for excellence", that is, action. Keywords: active vita, action, arché, politics, human condition.
НАУЧНЫЕ ЖУРНАЛЫ СИБИРСКОГО ОТДЕЛЕНИЯ РАН В ДИНАМИКЕ НАУЧНОЙ КОММУНИКАЦИИ ВТОРОЙ ПОЛОВИНЫ ХХ - ПЕРВЫХ ДВУХ ДЕСЯТИЛЕТИЙ XXI В
Authors: С.Н. ЛЮТОВ , Н.С. ЛИСОВСКАЯ 
Published: November 2024

В статье проанализированы особенности создания и основные тенденции развития научных журналов Сибирского отделения АН СССР/РАН в различные исторические периоды и проблемы их включения в меняющуюся систему научной коммуникации. На основе изучения перемен в научно-издательской практике 1990-х гг. и уточненных статистических показателей выявлены предпосылки количественного роста региональных академических журналов и их дифференциация по принципу учредительства. Цель статьи - показать специфику формирования издательской политики в процессе организации крупнейшего регионального центра академической науки и целенаправленную деятельность руководителей отделения по созданию издательской инфраструктуры, обеспечивающей потребности академических учреждений в представлении результатов научных исследований.
From the second half of the 20th to the early 21st century, academic science underwent a number of large-scale transformations that shaped the modern outlook of science and the mechanisms of scientific communication. Scientific journals, which reflected the complex processes of ongoing transformations while presenting the results of scientific research, are an important element of the information and communication environment. The information presented in the article shows the specifics of the organization of regional scientific publishing practice and its difference from the activities of central academic publishing houses. Under the Soviet science management system, the creation of each new scientific journal involved a complex procedure of approvals and affirmations, which hindered the initiatives of academic institutions to expand the presenting of scientific results in specialized scientific periodicals. The heads of the Siberian Branch, while organizing the publication of scientific journals, consistently sought a certain autonomy in the conduct of publishing policy and took measures to create their own publishing house and printing house. It only became possible to realize these ideas by the end of the 20th century. Subsequent events confirmed the correctness of this course. One of the features of the development of scientific periodicals in the 1990s - 2000s is the dynamics of quantitative growth of regional academic journals in the context of experiencing financial difficulties in building a new system of relations with foreign partners. The array of Russian scientific periodicals of those years grew mainly through regional scientific journals. The relative independence of scientific publishing activity made it possible to overcome the difficulties of the 1990s without significant losses, to create conditions for further growth of scientific periodicals, and to maintain stable positions of scientific journals of the Siberian Branch of the Russian Academy of Sciences in the changing system of scientific communication.
ИЗ ПЕРЕПИСКИ СИБИРСКИХ ИСТОРИКОВ: ПИСЬМА Н.Н. ПОКРОВСКОГО З.Я. БОЯРШИНОВОЙ (1972-1978 ГГ.)
Authors: Н.А. СТАРУХИН 
Published: November 2024

Введение в научный оборот и исследование источников личного происхождения, связанных с жизнью и научно-организаторской деятельностью выдающихся сибирских историков, является одним из важных и перспективных направлений гуманитарных исследований. Нами публикуются письма Н.Н. Покровского доктору исторических наук, профессору Томского государственного университета З.Я. Бояршиновой, отложившиеся в ее личном фонде в Государственном архиве Томской области. В письмах отражена роль Н.Н. Покровского в организации полевых археографических исследований, публикации источников по истории Сибири в 1970-е гг. В посланиях прослеживается характер взаимоотношений ученых, в значительной степени определявших развитие сибириведческих исследований в указанный период.
Studying and introducing sources of personal origin related to the lives and both scientific and organizational activities of Siberian historians into scientific circulation is one of the important and promising areas of humanitarian research. The letters of N.N. Pokrovsky to Doctor of Historical Sciences, Professor of Tomsk State University Z.Ya. Boyarshinova, deposited in her personal fond in the State Archive of the Tomsk Region, are being published in the present article. The letters reflect the role of N.N. Pokrovsky in organizing field archaeographic research, publishing sources on the history of Siberia in the 1970s. The messages trace the nature of the relationship between scientists who largely determined the development of Siberian research during this period.
СУПЕРЕЧНОСТІ ТА ПЕРСПЕКТИВИ ЕКОНОМІЧНОГО ЗРОСТАННЯ НА ІННОВАЦІЙНІЙ ОСНОВІ В УКРАЇНІ
Authors: ГЕЄЦЬ Валерій 
Published: November 2024

Розглянуто сучасні суперечності змісту й політики економічного зростання, де як ключову виокремлено проблему співвідношення між рівнем життя, досягнутим завдяки використанню орієнтованих переважно на отримання прибутку технологічних здобутків, і таким опануванням сил і ресурсів природи, яке в глобальному вимірі спричиняє тенденції до скорочення біорізноманіття і зміни клімату. Показано, що основні напрями розвитку передбачають пошук нового балансу у взаємодії природи і суспільства на засадах формування нового змісту економічної психології і переходу до розробки і використання нових технологій, орієнтованих на збереження біорізноманіття, стабілізацію кліматичних змін і забезпечення на таких умовах економічного зростання.
Охарактеризовано умови і можливості економічного зростання в Україні на основі, з одного боку, використання існуючих переваг технологічних можливостей (з ознаками глобального характеру і з урахуванням умов «зеленого переходу»), а з іншого – забезпечення змін умов соціального життя населення, яке ще під час війни проявляє бажання будувати кар’єру в іншому, відмінному від довоєнного напрямі, з переоцінкою цінностей і бажанням почати «нове життя» з новою роботою.
Розкрито зміст інноваційної і промислової політики щодо вирішення Україною «домашніх завдань» з промислового розвитку, успішність яких мають забезпечити сучасні засади економічної політики, здатної визначити ключові умови, дотримання і виконання яких формуватиме і реалізовуватиме держава, яка в першу чергу має орієнтуватися на майбутнє України як космічної держави. Це розширить наші можливості для міжнародної співпраці як у цій сфері, так і в частині забезпечення енергетичної безпеки шляхом розширення ядерної енергетики, біоенергетики, енергетичного машинобудування і взаємопов’язаних видів промислової діяльності.
Infections acquired in barbershops – A review
Authors: Britsch Jakob M. , Bereswill Stefan , Heimesaat Markus M. 
Published: November 2024

AbstractBarbershops are important venues for men to get their hair and beards done and hence, play an important role in men's social life. But barbershops can also be a source of infections. The barber's profession brings the barber into direct contact with customers who may carry pathogens, and contaminated instruments or skin-to-skin contacts might transmit infectious agents. Since barbers work with non-sterile and reusable sharp objects, a simple nick might facilitate blood-borne infections. In our review article we summarize current knowledge regarding barbershop-acquired infections including transmission routes and preventive measures. In fact, shaving in barbershops, particularly when reusing non-disinfected razor blades increases the transmission risk for the human immunodeficiency virus (HIV) and hepatitis B or C viruses. Furthermore, distinct bacteria like Staphylococcus aureus, fungi (in particular dermatophytic Trichophyton species) as well as ectoparasitic lice could be identified upon screening of the barbers' equipment and working places. However, knowledge regarding and compliance in hygiene practices varied considerably among barbers. Notably, since in certain countries barbershops are venues to contact sex workers, sexually transmitted diseases might also be acquired in barbershops. In conclusion, improving hygiene standards including disinfection of reusable equipment, and surveillance of the preventive measures would reduce the risk for barbershop-acquired infections.
Effect of coarse recycled aggregate with embedded fibres on the mechanical properties and microstructure of polypropylene fibre-reinforced concrete
Authors: Liu Guanzhi , Claramunt Josep , Hunger Martin , Tošić Nikola , de la Fuente Albert 
Published: November 2024

AbstractPrevious studies have shown the feasibility of using recycled aggregates in new concrete production. However, the recycling of fibre-reinforced concrete (FRC) introduces a novel challenge: the emergence of a new aggregate type that can be identified as recycled aggregate with embedded fibres. Therefore, in this study, in order to investigate the differences, the mechanical properties and microstructures of polypropylene fibre-reinforced concrete (PPFRC) made of natural coarse aggregate, coarse recycled aggregate and coarse recycled aggregate with embedded fibres were compared. Polypropylene fibre contents of 3 and 9 kg/m3 (0.33% and 1.0% by volume, respectively) were chosen for all concretes. The mechanical properties, including stress–strain behaviour in compression and flexural behavior, were tested. Scanning electron microscopy (SEM) was used to examine the microstructure and elucidate the effects of different aggregates on PPFRC properties. The results indicated that recycled aggregate with embedded fibres did not enhance compressive strength and elastic modulus compared to recycled aggregate without fibres. However, when the fibre content is low, its contribution to flexural behavior is significant, even surpassing that of PPFRC made with natural aggregate.
Cephalometric and facial photographic assessment, their correlations: A study in a tertiary health centre
Authors: Samridhi Richa , Garabadu Anand , Das Monalisa , Panigrahi Pragyna , Chandra Nayak Subash 
Published: November 2024

India as a country is still growing and luxurious cephalometric equipment is not available everywhere. There comes the importance of a low-cost photographic method. The photographic method can be beneficial where radiation is contraindicated or needs to be avoided. Further research needs to be conducted to test the diagnostic skill of the acquired photographs. This study was conducted to make orthodontic diagnosis and treatment accessible to the remote areas of the state of Odisha where there are no provisions for lateral cephalograms. Photography being a reproducible and non-invasive method has its access to every operator. The provision for photography can be done in every operatory setup without the risk of radiation hazards, even in remote areas, giving proper diagnosis aids in better treatment. Thus this study gives accessibility to diagnosis and further treatment for patients in the interior areas of the state. This study was conducted to compare thecorrelation between craniofacial measurements obtained from lateral cephalograms with similar anthropometric measurements from facial photographs in the Odisha population and to assess the reliability of both techniques(lateral cephalograms and facial photographs) and evaluate the predictability of cephalometric values through facial photographs. The study was an in-vitro cross-sectional study conducted on the patients presenting to the OPD of Hi-Tech Dental College and Hospital during 2 years tenure. The study was done on a sample of 100 individuals presenting to the hospital OPD in the age group of 10-35 years(mean age 22.38±3.342 years) age. The inclusion and exclusion criteria was decided. The photographic and radiographic analysis was done. The data was tabulated and statistical analysis was done with a statistical constant of p&#62;0.05. The study concluded that SNA, SNB, SN-MP(CP-MP’), Nasolabial angle, S-line to upper lip, and S-line to lower lip showed a good correlation among the two different methods with no sexual dimorphism. Photography being a reproducible and non-invasive method has its access to every operator. The provision for photography can be done in every operatory setup without the risk of radiation hazards, even in remote areas, giving proper diagnosis aids in better treatment. Thus this study gives accessibility to diagnosis and further treatment for patients in the interior areas of the state.
Spinal Echinococcosis With Paralysis Successfully Treated With Posterior Stabilization and Antiparasitic Drugs
Authors: Yabumoto Takuya , Ukeba Daisuke , Tanaka Shinya , Takakuwa Emi , Tanei Zen-ichi , Yamada Katsuhisa , Endo Tsutomu , Ohnishi Takashi , Tachi Hiroyuki , Sudo Hideki , Takahata Masahiko , Iwasaki Norimasa 
Published: November 2024

Case:
A 42-year-old woman presented with lateral chest and back pain. She was referred to our hospital after magnetic resonance imaging revealed a thoracic spine lesion. The initial examination revealed no obvious neurological deficits. A biopsy was performed, and enzyme-linked immunosorbent assay and western blotting confirmed Echinococcus infection. Paralysis and paresthesia developed, and stabilization and albendazole treatment were initiated. Postoperatively, the paralysis improved, and 2 years later, there was no lesion progression or symptom recurrence.

Conclusions:
Lesion resection is ideal for spinal echinococcosis; however, when resection is difficult, posterior stabilization and antiparasitic drugs may be effective.
Return-to-Play After Plasmodium falciparum Malaria in a Professional American Football Player
Authors: Mun Jeffrey S. , Ryan Edward T. , Whalen Jim , Martin Scott D. 
Published: November 2024

Case:
A 27-year-old male professional American football player presented to the emergency department with high-grade fever after recent travel to Nigeria. Blood smear confirmed Plasmodium falciparum malaria. After treatment and a 3-day hospital admission, the patient’s symptoms resolved, and he was discharged. Despite persistent splenomegaly at 6 weeks after discharge, the patient was cleared for on-field practice without contact. At 12 weeks after discharge, he was cleared to return to unrestricted play.

Conclusion:
Professional collision sport athletes with malaria and persistent splenomegaly should remain cautious about returning to contact play but may continue noncontact activities as tolerated to decrease the risk of deconditioning.
Tumor-Induced Osteomalacia—An Elusive and Often Delayed Diagnosis: A Case Report
Authors: Epley Rilee , Post Joel M. , Yousuf Adnan , Konopinski Jonathan , Grantham Michael , Kulyk Iryna 
Published: November 2024

Case:
A 62-year-old woman presented to an outside institution with a foot mass and pathologic femur fracture. Imaging studies demonstrated concern for a widely metastatic process. Bone biopsy demonstrated a granulomatous process with no evidence of malignancy. This case describes a unique presentation and a challenging diagnosis of tumor-induced osteomalacia (TIO) arising from a soft-tissue phosphaturic mesenchymal tumor (PMT) that required multiple subspecialist visits before reaching the final diagnosis.

Conclusion:
Surgical resection of the foot PMT was curative with no sequelae. This case demonstrates that TIO can present as mimicking a metastatic process.