bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meriel LeSueur Reflects on her Honors Colloquium Coursework
Authors: LeSueur Meriel , 2017 Class of 
Published: September 2018

Video Segments:
How did you first learn about honors colloquia? 0:04-0:52
What classes have you taken? 0:52-1:13
Do you have a favorite? 1:13-1:54
What have these classes taught you? 1:54-3:05
What is the most challenging part of these classes? 3:05-4:03
What are the benefits of these classes? 4:03-5:05
Advice for those choosing between departmental honors or colloquia? 5:05-5:55
What’s your advice for students going into colloquia? 5:55-6:45
The Syrian Refugee Crisis: Media Coverage and Humanitarian Response
Authors: Ritchie Kelsey , 2017 Class of 
Published: September 2018

Since 2011, the conflict in Syria has caused over 13.5 million Syrians to leave their homes, 4.8 million of which are refugees outside of Syria. Over the span of the six-year conflict, media coverage of the crisis has received both praise and harsh criticism. This paper focuses on the question of how media coverage of the crisis affect levels of response. The first part of this study is a content analysis of tweets from four news organizations. The analysis collects data on the number of tweets concerning the refugee crisis, as well as the content of those tweets. Secondly, the study uses an experimental design to test these findings. The researcher partnered with a local refugee organization to make policy recommendations in regards to social media campaigns. These two research designs found that tweets that contained visuals and were more anecdotal resulted in more response. However, the majority of coverage was more focused on numbers and statistics. Therefore, the conclusion and implications of this study found the need for a stronger relationship between news outlets and humanitarian aid organizations to 1) gain access to stories about refugees rather than solely hard news, and 2) to incite more tangible response.
Environmental Health Literacy Promotion Within the TCU Campus Community
Authors: Dohnalek Sophie , 2017 Class of 
Published: September 2018

An emerging field, environmental health literacy (EHL) aims to equip the public with information and risk communication tools that are applicable and easily understood. This study aimed to determine whether environmental health (EH) education impacts the likelihood of student, faculty, and staff to reduce or stop the use of products that are known to negatively impact health. To address the need for improved EHL, education sessions to promote EHL took place on an urban private university campus among students, faculty, and staff. Students, faculty, and staff on the TCU campus participated in an EH education session. Pender’s (1982) Health Promotion Model and evidence from the Agency for Toxic Substances and Disease Registry (ATSDR) informed session development.
Each session consisted of a presentation, hands on demonstration, and group discussion. Participants completed baseline surveys and discussion questions were recorded and transcribed. The investigator used descriptive and content analysis methods to evaluate these data. Twenty-seven participants (17 students, 10 faculty/staff) attended one of five group sessions. Of those, 81.5% reported no prior EH education; however, 77.8% indicated awareness of natural alternatives. An estimated 95% of participants felt the lesson motivated them to make informed choices and educate others. Key barriers to applying EHL in daily life included lack of understanding and education on the topic (37%), cost (33.3%), and brand familiarity (26%). Education sessions promoted EHL among students, faculty, and staff. These sessions have the potential to improve understanding of EH, and the overall health of the community by empowering individuals to make informed choices.
LiNK: The Role Gender Plays in Recess Activity Levels throughout the School Day
Authors: Schwene Diana , 2017 Class of 
Published: September 2018

The purpose of this research study was to focus on the physical activity differences during recess of grade one children. This study compared activity levels of grade one males and females during each of four unstructured recess times, scheduled at fifteen minutes each, and determined the activity patterns of children during each of these recess time periods. The results showed no significant differences for either category of data measured. The data categories included total recess step counts by day and total step counts for gender for each recess. The lack of significant difference supports the effectiveness of unstructured play over structured play in the recess setting. Unstructured play is a key aspect of the LiiNK project and the data shows that without balls to enable sporting behaviors and high adult intervention in play, both genders exhibit similar numbers of steps. It will be important to look at the differences between the intervention school results that were found in this study versus the recordings taken in a control school to further explore the impact of the LiiNK project as a whole.
O estado da arte sobre a formação docente para a diversidade cultural indígena
Authors: Fiuza Vivian Cristina Balan , Ramirez Germana Ponce de Leon 
Published: September 2018

O presente artigo expõe o resultado da pesquisa bibliográfica na qual se analisou o conteúdo dos resumos de periódicos, revistas, dissertações e teses defendidas em programas de pós-graduação (stricto sensu) com vistas à formação docente para a diversidade cultural indígena entre os anos de 2008 e 2017. Os dados foram obtidos a partir dos seguintes bancos de pesquisa: Biblioteca Digital Brasileira de Teses e Dissertações (BDTD), Google acadêmico, Scientific Eletronic Library Online (Scielo) e Comissão de Aperfeiçoamento de Pessoal do Nível Superior (Capes). O intuito desteartigo é de mapear as pesquisas realizadas nos últimos anos sobre a implantaçãoda Lei 11.645/08, que torna obrigatório o ensino da temática indígena no contexto escolar. Buscaram-se também informações sobre o aporte aos docentes da educação básica, os quais devem aplicar os conceitos em sala de aula. A pesquisa considerou os seguintes indicadores: problemática descrita nos resumos, tipo de pesquisa, área de estudo, ano da defesa, local de publicação, autores e os seguintes descritores: Lei 11.645/08, formação docente, diversidade cultural indígena e temática indígena na escola. Os resultados indicam que, dos 158.895 artigos encontrados, apenas 79 publicações se relacionam diretamente com a temática investigada, o que demonstra que não há uma quantidade significativa de artigos publicados sobre a temática indígena no contexto de formação de docentes não indígenas. Constatou-se, portanto, a relevância de empreender pesquisas sobre essa temática no sentido de conscientizar os docentes a valorizar a diversidade étnico-racial dos povos indígenas.
O estado da arte em Andragogia: uma análise nas produções científicas
Authors: Da Silva Maria Luísa De Carvalho Araújo , Torres Milton Luiz 
Published: September 2018

Com os crescentes avanços tecnológicos e científicos, o profissional do século 21 passou a ter necessidades específicas que diferem consideravelmente dos objetivos da educação básica, mais centrada em conteúdos introdutórios, e que segue padrões pedagógicos direcionados pelos professores. Além disso, a condição de adulto geralmente leva o educando a ter níveis de interesse e comprometimento que dependem de práticas pedagógicas mais ajustadas à sua madureza, necessidades profissionais e exigências pessoais. Isso ocorre principalmente nos cursos de graduação, pós-graduação e educação ou formação continuada. Decorre daí uma nova ênfase na andragogia, a maneira de aprender dos adultos, estabelecendo-se novas formas metodológicas de ensino e aprendizagem. O presente trabalho tem como objetivo analisar contribuições advindas de recentes pesquisas no Brasil sobre a Andragogia, a fim de se descrever introdutoriamente como a Andragogia tem sido praticada no nível do treinamento profissional nas diferentes áreas de atuação, observando-se quais procedimentos pedagógicos podem ser adaptados, aproveitados ou modificados para a melhoria e facilitação da aprendizagem. A metodologia empregada consistiu na eleição, a partir das principais bases de dados eletrônicas, de um artigo representativo de cada uma dentre cinco áreas de atuação profissional e numa breve descrição de seu conteúdo, caracterizando assim o estado da arte em Andragogia.
Sirolimus Therapy as Perioperative Treatment of Gorham-Stout Disease in the Thoracic Spine
Authors: Mo Andrew Z. , Trenor Cameron C. , Hedequist Daniel J. 
Published: September 2018

Case:
Gorham-Stout disease (GSD) is a rare entity that is marked by progressive osteolysis and bone resorption. A 14-year-old boy who was being followed for scoliosis presented with a marked curve progression and kyphoscoliosis. Imaging revealed osteolysis of the posterior elements and the ribs, suggestive of GSD. The structural compromise threatened spinal cord compression. Preoperative sirolimus therapy was initiated to stabilize the disease prior to corrective instrumentation. A biopsy specimen that was obtained at the time of instrumentation showed lymphatic vascular spaces consistent with GSD. Sirolimus therapy with the addition of bisphosphonate therapy was continued postoperatively.

Conclusion:
To our knowledge, this case report is the first to describe sirolimus therapy combined with surgery for GSD of the spine. The patient did well with consecutive medical optimization and surgical intervention, including postoperative sirolimus and bisphosphonate therapy.
Temporary Sternoclavicular Stabilization Using an Innovative Blocking Technique with Kirschner Wires for the Treatment of Posterior Sternoclavicular Joint Injury in Adolescent Patients
Authors: Ishii Nariyoshi , Matsumura Noboru , Iwamoto Takuji , Sato Kazuki , Nakamura Masaya , Matsumoto Morio 
Published: September 2018

Case:
A 15-year-old boy with a posterior physeal fracture-dislocation of the medial aspect of the clavicle and a 14-year-old boy with a posterior sternoclavicular joint dislocation were successfully treated with temporary sternoclavicular stabilization using an innovative blocking technique with Kirschner wires.

Conclusion:
When treating posterior sternoclavicular joint injuries, posterior instability should be securely stabilized. Temporary blocking stabilization of the sternoclavicular joint using Kirschner wires does not rigidly fix the sternoclavicular joint, but it prevents posterior displacement of the proximal aspect of the clavicle. This stabilizing technique is a simple, safe, and viable treatment option for adolescent patients with a posterior sternoclavicular joint injury.
Postoperative Seroma Formation After Posterior Cervical Fusion with Use of RhBMP-2
Authors: Wanderman Nathan R. , Drayer Nicholas J. , Tomov Marko , Reifsnyder Jeremy W. , Carlson Bayard , Robinson William , Kang Daniel G. , Freedman Brett 
Published: September 2018

Case:
We present 2 cases of postoperative seroma formation following posterior cervical fusion with the use of recombinant human bone morphogenetic protein-2 (rhBMP-2).

Conclusion:
Although some who advocate for the off-label use of rhBMP-2 in patients undergoing posterior cervical spine fusion believe it to be safe, relatively little has been published regarding complication rates. We believe that rhBMP-2 carries a risk of seroma formation in patients who undergo posterior cervical fusion, which necessitates the use of a postoperative drain. Surgeons should have a low threshold for obtaining postoperative magnetic resonance imaging in a symptomatic patient.
Combined Ligand-Based and Structure-Based Virtual Screening Approach for Identification of New Dipeptidyl Peptidase 4 Inhibitors
Authors: Upadhyay Jagatkumar , Gajjar Anuradha , Suhagia Bhanubhai N. 
Published: September 2018

Background:
Dipeptidyl Peptidase 4 (DPP 4) enzyme cleaves an incretin-based glucoregulatory
hormone Glucagon Like Peptide -1 from N-terminal where penultimate amino acid is either alanine
or proline. Several DPP 4 inhibitors, “gliptins”, are approved for the management of Type 2 Diabetes
or are under clinical trial. In the present study, combined pharmacophore and docking-based virtual
screening protocol were used for the identification of new hits from the Specs Database, which
would inhibit DPP 4.

Methods:
The entire computational studies were performed using the Discovery Studio v. 4.1 software
package, Pipeline Pilot v. 9.2 (Accelrys Inc.) and FRED v. 2.2.5 (OpenEye Scientific Software). Common
feature pharmacophore model was generated from known DPP 4 inhibitors and validated by Receiver
Operating curve analysis and GH-scoring method. Database search of Specs commercial database
was performed using validated pharmacophore. Hits obtained from pharmacophore search were
further docked into the binding site of DPP 4. Based on the analysis of docked poses of hits, 10 compounds
were selected for in- vitro DPP 4 enzyme inhibition assay.

Results:
Based on docking studies, virtual hits were predicted to form interaction with essential amino
acid residues of DPP 4 and have an almost similar binding orientation as that of the reference molecule.
Three compounds having Specs database ID- AN-465/42837213, AP-064/42049348 and AN-
465/43369427 were found to inhibit DPP 4 enzyme moderately.

Conclusion:
The present study demonstrates a successful utilization of in-silico tools in the
identification of new DPP 4 inhibitor, which can serve as a starting point for the development of novel
DPP 4 inhibitors.
Three Generations of β-blockers: History, Class Differences and Clinical Applicability
Authors: do Vale Gabriel T. , Ceron Carla S. , Gonzaga Natália A. , Simplicio Janaina A. , Padovan Júlio C. 
Published: September 2018

Background:Beta-adrenergic receptors are expressed in cardiomyocytes and activated by either noradrenaline released from sympathetic synapses or circulating catecholamines. Their corresponding receptors have three subtypes, namely, β1, β2 and β3, which are members of the G protein-coupled receptors (GPCRs) family. Activation of β1-adrenergic receptors causes various physiological reactions including cardiac contraction and renin secretion from juxtaglomerular cells of the kidney. Antagonists of β-adrenergic receptors, known as β-blockers, have been used effectively for over four decades and have beneficial effects in the treatment of cardiovascular diseases. There are three generations of β-blockers according to their pharmacological properties. Firstgeneration β-blockers are non-selective, blocking both β1- and β2-receptors; second-generation β- blockers are more cardioselective in that they are more selective for β1-receptors; and thirdgeneration β-blockers are highly selective drugs for β1-receptors. The latter also display vasodilator actions by blocking α1-adrenoreceptors and activating β3-adrenergic receptors. In addition, thirdgeneration β-blockers exhibit angiogenic, antioxidant, anti-proliferative, anti-hypertrophic and antiapoptotic activities among other effects that are still under investigation.Conclusion:The objective of this review is to describe the evolution observed during the development of the three distinctive generations, thereby highlighting the advantages of third-generation β- blockers over the other two drug classes.
Neuroprotective Effects of Trolox, Human Chorionic Gonadotropin, and Carnosic Acid on Hippocampal Neurodegeneration After Ischemiareperfusion Injury
Authors: Babahajian Asrin , Sarveazad Arash , Golab Fereshteh , Vahabzadeh Gelareh , Alizadeh Akram , Rasoolijazi Homa , Amini Naser , Entezari Maedeh , Soleimani Mansoureh , Katebi Majid , Haramshahi Seyed Mohammad Amin 
Published: September 2018

Introduction:
One of the serious complications of stroke is memory impairment, which is
considered as one of the complications of reperfusion of tissue. The present study was designed to
compare the effect of administration of Trolox, carnosic acid and Human Chorionic Gonadotropin
(HCG) immediately after reperfusion of the stroke tissue on the memory and hippocampal histology.

Method:
Ischemia-Reperfusion Model (IRI) was created by bilateral occlusion of the common carotid
artery for 15 minutes and the first dose was administered immediately after reperfusion. 10 days after
ischemia, passive avoidance memory test and apoptotic protein levels were evaluated.

Results:
Cerebral Ischemia perfusion reduced the time of latency in entering the dark box in the
ischemic group. Administration of Trolox and HCG increased this latency time, while treatment with
carnosic acid had no effect. Also, IRI significantly reduced the number of healthy cells in the hippocampus.
Administration of Trolox, carnosic acid and HCG increased the number of healthy cells and
decreased the expression of Caspase-3 and Bax, but significantly increased the expression of Bcl-2
compared to the ischemic group.

Conclusion:
Findings indicate the beneficial effects of HCG and Trolox on the improvement of memory
and the number of healthy cells in the hippocampal region. It is worth noting that the amount of
apoptosis in the hippocampus was significantly reduced by Trolox, HCG and Carnosic acid.
Perfil sociodemográfico y económico de estudiantes universitarios
Authors: Pérez-Contreras Blanca , González-Otero Katia , Polo-Bolaño Yaneth 
Published: September 2018

Objetivo. Este artículo es producto de la investigación que tuvo como objetivo identificar las características de la población estudiantil de pregrado y posgrado en la Corporación Universitaria del Caribe (CECAR), en Sincelejo (Sucre, Colombia), en el año 2016, mediante el análisis comparativo de variables demográficas, socio-familiares y económicas. Método. se utilizó un enfoque cuantitativo de corte positivista y tipo de estudio descriptivo; la muestra fue probabilística aleatoria simple de 1664 estudiantes, constituida por 851 de pregrado, modalidad presencial; 834 de la modalidad de educación a distancia, y 48 de especializaciones. El instrumento fue una encuesta construida con preguntas semiabiertas y cerradas, validado mediante juicio de expertos. Resultados. las características sociodemográficas no son significativamente diferenciales entre estudiantes de una y otra modalidad respecto a vínculos y dependencia del núcleo familiar, estado civil, procedencia y tipología familiar; en lo económico, prevalecen los estratos 1 y 2, el ingreso económico no asciende a los dos salarios mínimos legales vigente, el nivel y la modalidad educativa tampoco son factores diferenciadores. Conclusiones. el estudio permitió mayor conocimiento sobre las características o perfil de los estudiantes, lo que sirvió a la vez para la trazabilidad de líneas de acción que favorezcan la atención de los más vulnerables social y económicamente, así como a la reorientación del apoyo académico, psicosocial, becas y auxilios.
La construcción de la noción de Cosmovisión Maya en Guatemala
Authors: Cano Contreras Eréndira Juanita , Page Pliego Jaime T. , Estrada Lugo Erin I. J. 
Published: September 2018

Con el presente escrito deseamos contribuir a la reflexión del proceso de conformación histórica, política y cultural de la noción Panmaya de Cosmovisión Maya, la cual ha sido propuesta, difundida y practicada por intelectuales y activistas de los pueblos de origen maya asentados en territorio guatemalteco. Proponemos que este proceso resulta un ejemplo de apropiación, adopción y reinterpretación de un término académico migrado a contextos comunitarios y políticos. Esbozaremos el contexto en el que surge esta noción desde donde se enuncia la Cosmovisión Maya como concepto aglutinador de los procesos de fortalecimiento, visibilización, reivindicación y revitalización de la cultura maya en Guatemala en los años posteriores al conflicto armado interno.
La industria aeroespacial en México: características y retos en Sonora
Authors: Vázquez Ruiz Miguel Ángel , Bocanegra Carmen 
Published: September 2018

<p>El objetivo del presente texto es el aportar conocimientos sobre la situación y los retos de la industria aeroespacial en el estado de Sonora, México. Para ello se realizaron diversas entrevistas a funcionarios de empresas que arrojaron resultados como los siguientes: la industria se ha desplazado hacia localidades que ofrecen mejores condiciones para operar; el avance en los procesos de flexibilidad tecnológica reclama de una revisión en la capacitación de capital humano que se forma en las instituciones de educación superior de la entidad. No obstante, de ser uno de los cinco estados líderes a nivel nacional en la producción aeroespacial, la integración de cadenas productivas de valor aún es muy limitado y se concentran en el Nivel 2 de las cadenas de suministro.</p>
AWARENESS ABOUT LIFESTYLE DISEASES AMONGST THE SCHOOL GOING ADOLESCENTS OF DELHI
Authors: Sultana Kamar , Anjum Rubi , Wani Paras 
Published: September 2018

Objective: This study aims to assess the awareness about lifestyle diseases amongst the school going adolescents of different Gov. Schools of Delhi
Material and Methods: An interventional, quasi experimental pre-post design study was conducted in two Govt. schools of Delhi; Simple randomization technique was adopted to select the school from a list of school from west zone. Total number of students enrolled in the study was 110 at the time of Pre-test out of which 6 were drop outs and 104 students completed the study and was considered as the sample size. A self-designed questionnaire was used to assess the awareness about the lifestyle diseases.
Results: The study highlights the awareness level of adolescents about different lifestyle diseases and the effectiveness of the education program for improving the knowledge on lifestyle diseases among adolescents and thereby in prevention of lifestyle disorders.
Conclusion: School based interventions are required to improve the knowledge about lifestyle diseases in order to prevent these diseases correct practices can also be adopted.
Keywords: Lifestyle Diseases, Adolescents, Healthy lifestyle habits
NANOTECHNOLOGICAL APPROACH TO ENHANCE THE STABILITY AND BIOAVAILABILITY OF THE HERBAL DRUG "MURVA"
Authors: ARULANANDRAJ N , Gopal V , Dhivya S , Jayabalan G 
Published: September 2018

Murva (Maerua oblongifolia) contains numerous bioactive compounds that may provide multiple health benefits, including anti-microbial, anti-fungal, anti-pyretic and anti-diabetic. Most of the therapeutic effects of murva have been attributed due to the presence of triterpenoids and alkaloids, in their composition. Although these compounds have been shown promising therapeutic effects under in-vitro conditions, they met with limited efficacy in clinical settings due to various reasons such as poor oral absorption and bioavailability. Different techniques have been proposed to improve the stability and bioavailability of the herbal drugs. Among such strategies, nanoparticulate based drug delivery systems are novel and promising tools. In this study, chitosan nanoparticles containing Murva (CNP1-CNP3) were synthesized by ionic gelation technique, which resulting in particles size smaller than 650nm. The encapsulation efficiency of nanoformulations was over 41.5%. The nanoformulations exhibited slow and sustained in vitro release over 99% of drug from the Murva encapsulated chitosan nanoparticles after 24 hours. The synthesized nanoformulations were found to be a promising system for oral sustained administration of murva and also enhances its stability and bioavailability.
Keywords: Nanoparticles, Murva, chitosan, stability, bioavailability.