bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of textual and textual-pictorial glosses on incidental vocabulary learning in mobile-assisted listening
Authors: Shahipanah Arman , Khajavy Gholam Hassan , Elahi Shirvan Majid 
Published: November 2024

AbstractThis study investigated how multimedia glossing affects incidental vocabulary learning from a listening task on mobile devices. A total of 118 English language learners were asked to listen to a story with 25 glossed target words on their mobile phones. In order to examine the effects of different types of glossing, participants were divided into four groups with access to four glosses during their listening: L1 textual, L2 textual, L1 textual and pictorial, and L2 textual and pictorial. Two vocabulary tests (i.e. definition-supply test and meaning-recognition test) were administrated immediately after treatment and two weeks later to measure vocabulary gain for target words. The results indicated that participants who had access to L1 textual and pictorial glosses had significantly higher vocabulary gains than other conditions, especially in meaning-recall word knowledge. Finally, a detailed discussion of the findings was provided to explain the results based on the theoretical framework of the study.
Longitudinal change in the adjective intensifier system of Hexagonal French
Authors: Kunkel Scott 
Published: November 2024

AbstractIntensifiers are known for their dynamic nature, due in part to the expressive function they serve. However, while the quantitative patterning of English intensifiers has been studied extensively, the intensifier system of French has yet to be well documented. This study therefore examines intensifier use from a variationist sociolinguistic perspective in the ESLO corpus of spoken Hexagonal French. The quantitative distributions of adjective intensifiers are compared across two corpora collected in 1970 and 2010. Results show a significant decrease in intensification rate over time. Analysis of individual intensifiers show some to have decreased in use over time (e.g. très, tellement), others to have increased (e.g. vraiment, tout), and others to appear only in the later sample (e.g. super, hyper). Longitudinal change is also found in the adjectival function (predicative vs. attributive) and collocational width of intensifiers. Relating to social factors, no significant gender difference is found between female and male speakers’ intensification rate over time. Furthermore, très dominates as the preferred intensifier among older generations, while younger speakers favour more varied intensifiers. Analyzing such changes in the use of intensifiers over the past half century contributes to a better understanding of the structure and development of the French intensifier system.
Power line density and habitat quality: key factors in Canarian houbara bustard decline
Authors: Ucero Alberto , Alonso Juan C. , Palacín Carlos , Abril-Colón Inmaculada , Álvarez-Martínez José M. 
Published: November 2024

Summary
Species’ declines are caused by a combination of factors that affect survival and/or breeding success. We studied the effects of a set of environmental and anthropogenic variables on the disappearance of Canarian Houbara Bustards Chlamydotis undulata fuertaventurae on Fuerteventura (Canary Islands), once the main stronghold of this endangered bird. Of 83 male display sites detected in 1997–1998, only 29 remained occupied in 2020–2021 (a 65% decrease in only 23 years). We compared habitat quality, density of conspecifics, other steppe birds and crows, presence of human infrastructure, and degree of environmental protection between these 29 extant sites and the 54 extinct sites using univariate analyses and generalised linear models (GLMs). The most influential variable in the abandonment of display sites was the Normalised Difference Vegetation Index (NDVI), an indicator of green vegetation productivity, which suggests a strong effect of habitat aridification due to climate change on the population’s extinction process. Powerline density was the second most important factor. This suggests that houbaras have survived where a greater abundance of food resources has enabled a higher breeding success, and where powerline fatalities have caused lower mortality over the years. Higher densities of houbaras, and other steppe birds and crows at extant display sites confirmed the better habitat quality in these areas. Extant display sites, located generally in protected areas, also had lower densities of human infrastructure (e.g. buildings, roads). We discuss the conservation implications of these results and provide management recommendations for this endangered subspecies.
The effect of rapamycin treatment on mouse ovarian follicle development in dehydroepiandrosterone-induced polycystic ovary syndrome mouse model
Authors: Yildirim Ecem , Onel Tugce , Agus Sami , Gunalan Elif , Yilmaz Bayram , Aydin Mehmet Serif , Yaba Aylin 
Published: November 2024

AbstractPolycystic ovary syndrome (PCOS) is a complex reproductive and endocrine disorder affecting 5–10% of women of reproductive age, but the pathophysiology of PCOS still remains unknown. Here, the aim of our study was to analyze the effects of rapamycin treatment that may regulate impaired hormonal levels and folliculogenesis in dehydroepiandrosterone (DHEA)-treated PCOS mouse. We hypothesized that rapamycin may ameliorate the negative effects of PCOS in DHEA-induced PCOS mouse model. The target of rapamycin (TOR) gene product is a serine/threonine kinase that has been implicated in the control of cell growth, proliferation and autophagy, and rapamycin is a potent inhibitor of mTORC1 pathway. In this study, for the first time, mTORC1 and activation products are presented at protein and mRNA levels after rapamycin treatment in DHEA-induced PCOS mouse ovary. We showed that rapamycin treatment may regulate follicular development, hormonal levels and provide ovulation in DHEA-induced PCOS mouse. Additionally, we assessed decreased primordial follicle reserve, increased number of primary and secondary follicles, corpus luteum structure forms again after 10 days of rapamycin treatment. This study presented here suggests rapamycin treatment regulates hormonal phenotype and folliculogenesis in the ovary and also mTOR signalling pathway in granulosa cells of DHEA-induced PCOS mouse ovary which may have potential to attenuate understanding the mechanism of dominant follicle selection and anovulatory infertility.
Identification of clinical risk factors for coronary artery lesions in children with Kawasaki disease: a retrospective cohort study
Authors: Yang Xiangna , Zou Jiayi , Nie Hao , Zhang Gang , Liao Yin , Deng Jian , Wang Yanfei 
Published: November 2024

AbstractBackground:Coronary artery lesions are the most severe complications of Kawasaki disease. Despite recent advances, evidence of the association between risk factors and coronary artery lesion is lacking. In this study, we demonstrated the potential clinical indicators that could assist to evaluate the prevalence of coronary artery lesion among paediatric patients with Kawasaki disease.Methods:We retrospectively enrolled 260 paediatric patients with Kawasaki disease. Patients with coronary dilation, coronary aneurysm, and intimal thickening of coronary arteries were included in this study. Medical records of each patient were collected. Logistic regression analysis was performed to explore risk factors and the occurrence of coronary artery lesion in patients with Kawasaki disease.Results:Respectively, 64 (24.6%), 39 (15%), and 56 patients (21.5%) of the participants had coronary dilation, coronary aneurysm, and intimal thickening of coronary arteries. Univariate analysis revealed that age, gender, duration of fever, time of initial use of intravenous immunoglobulin, erythrocyte sedimentation rate, white blood cell counts, time of platelet increase, the maximum value of platelet, albumin, and immunoglobulin G level was associated with coronary artery lesion. In multivariable logistic analysis, those younger and mainly males were associated with all three outcomes of coronary artery lesion, lower serum albumin levels, and later initial use of intravenous immunoglobulin were linked to a higher risk of coronary dilation and coronary aneurysm.Conclusions:The potential risk factors that could be used to estimate the occurrence of coronary artery lesion in Kawasaki disease patients are young age, male, lower serum albumin lever, and later initial use of intravenous immunoglobulin. However, long-term follow-up and multi-centre studies are required to verify our findings in the future.
Extreme comovements and downside/upside risk spillovers between oil prices and exchange rates
Authors: Ning Cathy , Xu Dinghai 
Published: November 2024

Abstract
This paper examines the dependence structure and risk spillovers between oil prices and exchange rates in both oil-exporting and oil-importing countries. Using a flexible dependence switching copula model, we analyze both positive and negative dependence and transitions between the dependence regimes. Additionally, we investigate the directional risk spillovers between oil and currency markets in both their downsides and upsides. Based on empirical data from 1999 to 2024 for major oil-exporting and oil-importing countries, we find that oil price-currency dependence is predominantly positive for oil-exporting countries, with infrequent transitions, but mainly negative for oil-importing countries, with frequent transitions between the two dependence regimes. These transitions often occur around crisis or war times. Furthermore, we observe that during downturns in the oil market, tail dependence between oil prices and currencies becomes more pronounced than during upturns. Our results indicate the presence of risk spillovers between oil and currency markets, with the downside spillover effects outweighing the upside ones. Moreover, we find that risk spillover is stronger from oil markets to currency markets than the reverse direction. These insights substantially enrich the existing literature and would offer valuable implications for effective risk management strategies and policymaking.
Bacteria Acidithiobacillus ferrooxidans, terrestrial analogue of extraterrestrial microorganisms?
Authors: Slowik Grzegorz Piotr , Richer Renee , Stryjska Aleksandra Zofia , Dabrowski Pawel 
Published: November 2024

Abstract
In this comprehensive review, Acidithiobacillus ferrooxidans, an acidophilic bacterium, has been thoroughly examined as a plausible analogue for microbial life in Venus's lower cloud layer. Given its ability to adapt to extreme conditions, including low pH environments and metal-rich settings, Acidithiobacillus ferrooxidans is considered a promising candidate for studying life analogues in Venus's clouds. This article comprehensively analyses the bacterium's distinctive phenotypic and genotypic features, investigating its metabolic pathways, adaptive strategies and potential ecological niche within Venusian cloud ecosystems. After careful consideration of the environmental parameters characterizing Venus, the unidentified UV absorber in its clouds, and the prospects for microbial life, this review underscores the imperative nature of future Venus missions and the pivotal role that Acidithiobacillus ferrooxidans may play in exploring the possible habitability of Venus and advancing astrobiological research.
Greening‐Induced Biophysical Impacts Lead to Earlier Spring and Autumn Phenology in Temperate and Boreal Forests
Authors: Guo Jing , Wang Jinmei , Qiao Yuxin , Huang Xu , Smith Nicholas G. , Liu Zhiyong , Zhang Rui , Chen Xiuzhi , Wu Chaoyang , Peñuelas Josep , Chen Lei 
Published: November 2024

AbstractTree phenology, the timing of periodic biological events in trees, is highly sensitive to climate change. Previous studies have indicated that forest greening can impact the local climate by modifying the seasonal surface energy budget. However, the understanding of tree phenological responses to forest greening at large spatial scales remains limited. Utilizing satellite‐derived phenological and leaf area index data spanning from 2001 to 2021, herein we show that forest greening led to earlier spring and autumn phenology in both temperate and boreal forests. Our findings demonstrated that forest greening during winter and spring contributed to a reduction in surface albedo, resulting in biophysical warming and consequently advancing spring leaf phenology. Conversely, forest greening in summer and autumn induced biophysical cooling through increased evapotranspiration, leading to an earlier onset of autumn leaf phenology. Our findings highlight the significant impact of forest greening‐induced local seasonal climate changes on shaping tree phenology in temperate and boreal forests. It is crucial to consider these greening‐induced alterations in microclimate conditions when modeling changes in tree phenology under future climate warming scenarios.
The Multi‐Segment Complexity of the 2024 MW ${M}_{W}$ 7.5 Noto Peninsula Earthquake Governs Tsunami Generation
Authors: Kutschera Fabian , Jia Zhe , Oryan Bar , Wong Jeremy Wing Ching , Fan Wenyuan , Gabriel Alice‐Agnes 
Published: November 2024

AbstractThe 1 January 2024, moment magnitude 7.5 Noto Peninsula earthquake ruptured in complex ways, challenging analysis of its tsunami generation. We present tsunami models informed by a 6‐subevent centroid moment tensor (CMT) model obtained through Bayesian inversion of teleseismic and strong motion data. We identify two distinct bilateral rupture episodes. Initial, onshore rupture toward the southwest is followed by delayed re‐nucleation at the hypocenter, likely aided by fault weakening, causing significant seafloor uplift to the northeast. We construct a complex multi‐fault uplift model, validated against geodetic observations, that aligns with known fault system geometries and is critical in modeling the observed tsunami. The simulations can explain tsunami wave amplitude, timing, and polarity of the leading wave, which are crucial for tsunami early warning. Upon comparison with alternative source models and analysis of 2000 multi‐CMT ensemble solutions, we highlight the importance of incorporating complex source effects for realistic tsunami simulations.
Proton Cyclotron Waves and Pickup Ion Ring Distribution Instabilities Upstream of Mars
Authors: Cheng Kun , Liu Kaijun , Mousavi Ameneh , Cowee Misa , Zheng Xianming , Zhou Jingyi , Wang Yan , Liu Yuqi , Wang Xinye 
Published: November 2024

AbstractProton cyclotron waves (PCWs) upstream of Mars are thought to be associated with the instabilities of pickup ions. The instabilities of pickup ions of ring distributions have larger maximum growth rates compared with beam distributions. However, observations revealed a notably‐reduced occurrence rate of PCWs for pickup ions of ring distributions. Linear instability analysis and a corresponding two‐dimensional particle‐in‐cell (PIC) simulation are performed to investigate the instabilities of pickup ion ring distributions upstream of Mars. Linear instability analysis indicates that a pickup ion ring distribution is unstable to the ion cyclotron, ion Bernstein, and mirror instabilities. The corresponding PIC simulation confirms the linear analysis results and further demonstrates that the pickup ions are scattered toward an isotropic shell distribution by the waves excited. Interestingly, the saturation energy of the waves is much lower than that driven by a corresponding pickup ion beam distribution, and mirror waves eventually dominate the system.
The Relative Importance of Ocean Advection and Surface Heat Fluxes During the Madden–Julian Oscillation in a Coupled Ocean–Atmosphere Model
Authors: Karlowska E. , Matthews A. J. , Webber B. G. M. , Graham T. , Xavier P. 
Published: November 2024

AbstractIntraseasonal variability of ocean surface mixed layer temperature (MLT) in the tropics can be linked to the Madden–Julian Oscillation (MJO), the main source of intraseasonal atmospheric variability in the tropics. Here, we conduct a boreal winter mixed layer heat budget using 10‐day forecast composites of a coupled ocean–atmosphere Numerical Weather Prediction model of the UK Met Office to reveal that ocean advection plays a major role in modulating intraseasonal anomalies of MLT over the tropical Indian Ocean and the Maritime Continent. Large scale ( 10) intraseasonal anomalies of MLT ( 0.1 C) are driven by net surface heat flux. Ocean advection dominates at smaller horizontal scales ( 1), contributing up to 0.5 C to the intraseasonal MLT anomaly. Prior to the development of the enhanced MJO convection in the western Indian Ocean (phases 8 and 1), ocean advection reinforces the net heat flux warming in this region. However, ocean advection opposes the net heat flux warming in the Maritime Continent prior to the development of suppressed MJO convection in this region. When the MJO convection develops over the central Indian Ocean (phase 3), ocean advection (net surface heat flux) drives the intraseasonal MLT anomalies in the western Indian Ocean (central Indian Ocean and the Maritime Continent). Our results demonstrate the importance of ocean dynamics during the initiation and growth of the MJO, and raise implications for models that do not resolve these processes.
Evaluation of two different self-disinfection alginate impression material
Authors: Bendary Islam M. , Omar Alaa A. , Goda Reham M. , Ali Ahmed A. , Lotfy Kareem A. , Shohayeb Mohamed M. 
Published: November 2024

Abstract
Objective
This study was conducted to evaluate the antimicrobial efficacy and mechanical properties of two experimental self-disinfecting alginate preparations utilising two different antimicrobial agents; povidone-iodine and silver nanoparticles.

Methods
Alginate moulds were assigned into three groups. Additives-free control group, povidone-iodine-containing group, and silver nanoparticle-containing group. Discs from each group were obtained and assessed for their antimicrobial activities by the disc diffusion method against Staphylococcus aureus, Escherichia coli, and Candida albicans. For the elastic recovery analysis, each group was divided into 6 samples. Each sample was mixed according to its group specification and subjected to surface detail reproduction and elastic recovery according to ISO 1563:1990 specifications. All data were expressed as mean ± standard deviation for each group at the significance level of P < 0.05.

Results
Results revealed that the experimental self-disinfection alginate possessed broad-spectrum antimicrobial activities against the tested microorganisms, compared to the control group. No statistically significant differences in elastic recovery values between all tested groups (P < 0.05) were observed. For surface detail reproduction, all samples reproduced the 50 μm line.

Conclusion
Povidone-iodine as well as silver nanoparticles could be used efficiently for the sanitization of alginate moulds without adverse effects on detail accuracy or elastic recovery of the impression material.
OTUB1 regulation of ferroptosis and the protective role of ferrostatin-1 in lupus nephritis
Authors: Liu Chen , Gan Yu-hui , Yong Wei-jing , Xu Hong-de , Li Yong-chun , Hu Hui-miao , Zhao Zhan-zheng , Qi Yuan-yuan 
Published: November 2024

AbstractLupus nephritis (LN) is a prevalent and severe manifestation of systemic lupus erythematosus (SLE), leading to significant morbidity and mortality. OTUB1, a deubiquitinating enzyme, has emerged as a potential therapeutic target due to its role in cellular protection and regulation of ferroptosis, a form of cell death linked to LN. Our study revealed significantly reduced OTUB1 expression in the glomeruli of LN patients and podocytes, correlated with disease severity. CRISPR/Cas9-mediated OTUB1 knockout in podocytes resulted in pronounced injury, indicated by decreased levels of nephrin and podocin. Ferrostatin-1 treatment effectively mitigated this injury, restoring SLC7A11 expression and significantly reducing MDA levels, Fe2+ levels, BODIPY C11 expression, and normalized cysteine and glutathione expression. In the MRL/lpr mouse model, Ferrostatin-1 significantly improved renal function decreased proteinuria, and ameliorated renal histopathological changes, including reduced glomerular endothelial swelling, mesangial cell proliferation, and leukocyte infiltration. These results underscore the protective role of Ferrostatin-1 in modulating the pathogenesis of LN. OTUB1 plays a crucial protective role against podocyte injury in LN by regulating ferroptosis. Ferrostatin-1 effectively mitigates podocyte damage induced by OTUB1 deficiency, suggesting that targeting ferroptosis could be a promising therapeutic strategy for LN.
Stem cell transplantation extends the reproductive life span of naturally aging cynomolgus monkeys
Authors: Yan Long , Tu Wan , Zhao Xuehan , Wan Haifeng , Wu Jiaqi , Zhao Yan , Wu Jun , Sun Yingpu , Zhu Lan , Qin Yingying , Hu Linli , Yang Hua , Ke Qiong , Zhang Wenzhe , Luo Wei , Xiao Zhenyu , Chen Xueyu , Wu Qiqian , He Beijia , Teng Man , Dai Shanjun , Zhai Jinglei , Wu Hao , Yang Xiaokui , Guo Fan , Wang Hongmei 
Published: November 2024

AbstractThe ovary is crucial for female reproduction and health, as it generates oocytes and secretes sex hormones. Transplantation of mesenchymal stem cells (MSCs) has been shown to alleviate pathological ovarian aging. However, it is unclear whether MSCs could benefit the naturally aging ovary. In this study, we first examined the dynamics of ovarian reserve of Chinese women during perimenopause. Using a naturally aging cynomolgus monkey (Macaca fascicularis) model, we found that transplanting human embryonic stem cells-derived MSC-like cells, which we called M cells, into the aging ovaries significantly decreased ovarian fibrosis and DNA damage, enhanced secretion of sex hormones and improved fertility. Encouragingly, a healthy baby monkey was born after M-cell transplantation. Moreover, single-cell RNA sequencing analysis and in vitro functional validation suggested that apoptosis, oxidative damage, inflammation, and fibrosis were mitigated in granulosa cells and stromal cells following M-cell transplantation. Altogether, these findings demonstrate the beneficial effects of M-cell transplantation on aging ovaries and expand our understanding of the molecular mechanisms underlying ovarian aging and stem cell-based alleviation of this process.
Bacterial toxins induce non-canonical migracytosis to aggravate acute inflammation
Authors: Li Diyin , Yang Qi , Luo Jianhua , Xu Yangyushuang , Li Jingqing , Tao Liang 
Published: November 2024

AbstractMigracytosis is a recently described cellular process that generates and releases membrane-bound pomegranate-like organelles called migrasomes. Migracytosis normally occurs during cell migration, participating in various intercellular biological functions. Here, we report a new type of migracytosis induced by small GTPase-targeting toxins. Unlike classic migracytosis, toxin-induced migrasome formation does not rely on cell migration and thus can occur in both mobile and immobile cells. Such non-canonical migracytosis allows the cells to promptly respond to microbial stimuli such as bacterial toxins and effectors and release informative cellular contents in bulk. We demonstrated that C. difficile TcdB3 induces liver endothelial cells and Kupffer cells to produce migrasomes in vivo. Moreover, the migracytosis-defective Tspan9‒/‒ mice show less acute inflammation and lower lethality rate in the toxin challenge assay. Therefore, we propose that the non-canonical migracytosis acts as a new mechanism for mammalian species to sense and exacerbate early immune response upon microbial infections.