bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tumor vasculature: a sally port for inhibiting cancer cell spreading
Authors: Qian Chao‐Nan , Pezzella Francesco 
Published: August 2018

AbstractThe close relationship between metastasis and establishment of tumor vasculature has inspired enormous research interests aiming to suppress metastasis via inhibiting the development of tumor vasculature. International experts gathered in Guangzhou, China on May 10–12, 2018 in The 4th International Meeting of Cancer and Blood Vessels to discuss the multiple ways for solid tumors to establish their vasculature. Vessel co‐option is a mean by which a solid tumor takes advantage of the existing or newly induced blood vessels in the surrounding normal tissues to sustain tumor growth and metastasis. The underlying mechanisms of vessel co‐option, the roles of pericyte, and the potential novel therapeutic targets have been discussed in the meeting.
Disparities in Cervical Cancer Screening Among Women With Disabilities: A National Database Study in South Korea
Authors: Shin Dong Wook , Lee Jeong-Won , Jung Jin Hyung , Han Kyungdo , Kim So Young , Choi Kui Son , Park Jong Heon , Park Jong Hyock 
Published: August 2018

Purpose Using the linked administrative database in Korea, we investigated (1) whether cervical cancer screening participation differed by the presence of varying degrees and types of disability; (2) trends in the cervical cancer screening rate relative to disabilities over time; and (3) factors associated with cervical cancer screening. Methods We linked national disability registration data with national cancer screening program data. Age-standardized participation rates were analyzed for each year during the period 2006 to 2015, according to the presence, type, and severity of disabilities. Factors associated with undergoing cervical cancer screening were examined by multivariate logistic regression with the most current data (ie, 2014 to 2015). Results The age-adjusted screening rate for cervical cancer screening in women with disabilities increased from 20.8% in 2006% to 42.1% in 2015 (change, +21.3%); however, among women without disabilities, it increased from 21.6% to 53.5% (change: +31.9%) during that time. Disability was associated with a lower screening rate (adjusted odds ratio [aOR], 0.71; 95% CI, 0.71 to 0.72). Screening rates were markedly lower in women with severe disabilities (aOR, 0.42; 95% CI, 0.42 to 0.42) and women with autism (aOR, 0.06; 95% CI 0.03 to 0.11), intellectual disability (aOR, 0.25; 95% CI, 0.25 to 0.26), brain injury (aOR, 0.311; 95% CI, 0.31 to 0.32), ostomy (aOR, 0.36; 95% CI, 0.33 to 0.38), or mental disorder (aOR, 0.43; 95% CI, 0.42 to 0.44). Conclusion Despite the availability of free screening, a significant disparity was found in cervical cancer screening participation, especially in women with severe disabilities and those with mental disabilities. The identification of barriers associated with decreased screening rates in women with disabilities has important implications for the design of tailored interventions and health care policies to improve cervical cancer screening and outcomes in this vulnerable population.
Unusual Headache Disorders
Authors: Starling Amaal Jilani 
Published: August 2018

ABSTRACT

PURPOSE OF REVIEW
Unusual headache disorders are less commonly discussed and may be misdiagnosed. These headache disorders frequently have a benign natural history; however, without reassurance, therapeutic education, and treatment, they can negatively affect the health and function of patients.

RECENT FINDINGS
This article reviews the clinical features, diagnosis, workup, and proposed treatments for several unusual headache disorders including primary cough headache, primary headache associated with sexual activity, primary exercise headache, cold-stimulus headache, primary stabbing headache, nummular headache, hypnic headache, and headache attributed to travel in space. Exploding head syndrome is also discussed, which is a sleep disorder commonly confused with a headache disorder.

SUMMARY
Unusual headache disorders are usually benign, yet without the correct diagnosis can be very worrisome for many patients. Through greater awareness of these headache disorders, neurologists can evaluate and effectively manage unusual headache disorders, which offers significant benefits to patients and practice satisfaction to neurologists.
Acute Treatment of Migraine
Authors: Vargas Bert B. 
Published: August 2018

ABSTRACT

PURPOSE OF REVIEW
This article provides a framework to help providers formulate a plan for the acute treatment of migraine. Topics covered include the cost-effective patient-centered approach known as stratified care and a summary of evidence-based treatment options that are currently available. Strategies for improving treatment response, troubleshooting suboptimal results, and addressing the needs of special populations are also reviewed.

RECENT FINDINGS
Both the American Headache Society and the Canadian Headache Society have released evidence-based assessments and reviews of acute treatments for migraine that can be used to help guide treatment decisions. Although several older medications have been re-released with new formulations or new delivery systems, several new medications have also become available or are in the final phases of study, further increasing the number of options available for patients.

SUMMARY
The acute management of migraine should incorporate a stratified care model in concert with evidence-based treatment options. The response to treatment should be monitored regularly, and measures should be taken to identify suboptimal tolerability or efficacy.
Diagnostic value of iterative reconstruction algorithm in low kV CT angiography (CTA) with low contrast medium volume for transcatheter aortic valve implantation (TAVI) planning: image quality and radiation dose exposure
Authors: Talei Franzesi Cammillo R , Ippolito Davide , Riva Luca , Fior Davide , Cangiotti Cecilia , Sironi Sandro 
Published: August 2018

Objective:
To evaluate image quality and radiation dose exposure of low-kV (100 kV) and low contrast medium (CM) volume CT angiography (CTA) in patients candidate to Transcatheter Aortic Valve Implantation (TAVI), in comparison with standard CTA protocol.

Methods:
79 patients candidate for TAVI were prospectively enrolled in this study and examined with 256-MDCT. 42 patients were evaluated using study-group protocol (100 kV; whole-body retrospective ECG-gating; with 50 ml of CM; iterative reconstruction algorithm) while 37 patients underwent a standard CTA study (120 kV; ECG-gating for chest; 100 ml of CM; FBP reconstruction). Overall image quality was evaluated using a 4-point scale. Vascular enhancement (HU) was then assessed in each patient by manually drawing multiple ROIs in lumen of 7 segments of the whole aorta. The radiation dose exposure of both groups was calculated and all data were compared and statistically analyzed.

Results:
On low-kV protocol, higher mean attenuation values were achieved in all the measurements as compared to standard protocol. There were no significant differences in the image quality evaluation in both groups. Mean radiation dose value of study group was significantly lower than in control group (reduction of 20%).

Conclusion:
Low kV and low CM volume CTA protocols allow TAVI planning to be carried out with high quality images and a significant reduction in the radiation dose as compared to the standard CTA protocol.

Advances in knowledge:
Low-kV CTA for pre-operative assessment of patients candidates for TAVI, permits to achieve a significant reduction of radiation dose exposure and contrast medium volume, reducing the risk of contrast induced nephropathy.
Simulation-based learning: a case study, Part 1
Authors: Dow Angela 
Published: August 2018

Clinical simulation can be used in the university to provide an educational environment similar to that of the clinical area. Therefore, it is expected that simulation-based learning (SBL) will enable student midwives to apply their learning more easily when they return to the workplace ( Wilford and Doyle, 2006 ). This is the first of three articles presenting the findings from a study to explore the real setting where there is opportunity to apply simulation. A small scale qualitative instrumental case study consisting of midwifery lecturers, first year midwifery students and mentor midwives was undertaken. A conceptual framework informed the research questions in relation to how clinical simulation was perceived to prepare the student midwife for clinical practice, how it was utilised in the clinical situation and its influence on work-based learning. Methods of data collection included one-to-one interviews and focus groups. The main findings demonstrated that the application of clinical simulation was largely seen as a transfer of practical skills, even though a holistic approach to learning had initially taken place in the university. Other main themes centred on the realism associated with simulation and its preparatory value for clinical practice. There was also evidence to suggest that simulation supported the role of clinical mentors in practice and enhanced students' work-based learning. Over the series of three articles, these main findings will be reported. In this first article, the findings are presented in relation to the role of SBL in preparing student midwives for practice placement.
The development of Response Strategies Scale (RSS): Validity and reliability study<p>Tepki Stratejileri Ölçeği’nin (TSÖ) geliştirilmesi: Geçerlik ve güvenirlik çalışması
Authors: Asıcı Esra , Karaca Rengin 
Published: August 2018

In this study it was aimed to develop a scale for determining response strategies to damaging acts of adolescents in interpersonal relations. In line with this aim, a-70-item trial form was constituted based on The Integrated Forgiveness Model suggested by Scobie and Scobie (1998). The study was conducted with 1255 high school students. The explanatory factor analysis revealed a construct with five factors which explains 51.29% variance of total score. These factors were named as “reinterpret self-concept”, “seek retribution” “seek revenge”, “pseudoforgiveness”, “forgiveness”. Item loads ranged from .47 to .82. The results of confirmatory factor analysis confirmed the construct with 28 items and 5 factors (S-BX2=1.66, RMSEA=.05, SRMR=.06, GFI=.90, AGFI=.87, NFI=.94, NNFI=.97, CFI=.98). Cronbach alpha coefficients varied between .65 and .90. In the study of criterion-related validity, it was determined that Response Strategies Scale was positively and significantly related with aggressive behaviors and problem solving subscales of conflict resolution behavior scale. Extended English summary is in the end of Full Text PDF (TURKISH) file.ÖzetBu çalışmada ergenlerin kişilerarası ilişkilerde yaşanan zarar verici eylemlerle başa çıkmada kullandıkları tepki stratejilerini belirlemek için bir ölçme aracının geliştirilmesi amaçlanmıştır. Bu amaçla, Scobie ve Scobie’nin (1998) Bütünleştirilmiş Affetme Modeline dayalı olarak 70 maddelik bir deneme form oluşturulmuştur. Çalışma 1255 lise öğrencisiyle yürütülmüştür. Analizlerde açıklayıcı ve doğrulayıcı faktör analizi, pearson momentler çarpımı korelasyonu, ve Cronbach alfa güvenirlik katsayısıyı teknikleri kullanılmıştır. Açıklayıcı faktör analizi sonuçları toplam varyansın %51.29’unu açıklayan beş faktörlü bir yapı ortaya çıkarmıştır. Bu faktörler “benlik kavramını yeniden yorumlama”, “cezalandırma arayışı”, “intikam arayışı”, “sahte affetme” ve “affetme” olarak adlandırılmıştır. Madde faktör yüklerinin .47 ile .82 arasında değiştiği belirlenmiştir. Doğrulayıcı faktor analizi sonuçları 28 madde ve beş faktörden oluşan yapıyı doğrulamıştır (S-BX2=1.66, RMSEA=.05, SRMR=.06, GFI=.90, AGFI=.87, NFI=.94, NNFI=.97, CFI=.98). Ölçeğin Cronbach alfa iç tutarlık katsayılarının .65 ile .90 arasında değiştiği saptanmıştır. Ölçüt bağıntılı geçerlik çalışmasında, Tepki Stratejileri Ölçeği ile çatışma çözme davranışlarını belirleme ölçeğinin saldırgan davranışlar ve problem çözme davranışları alt boyutları arasında ilişki olduğu belirlenmiştir.
Oxidation Activation Energy of Titanium Alloy Based on TiAl(γ) Intermetalic Phase
Authors: Małecka J. 
Published: August 2018

Abstract
The present paper deals with the analysis of the course of oxidation of the cyclic Ti-46Al-7Nb-0.7Cr-0.1Si-0.2Ni alloy in a hot air atmosphere in the temperature range of 875-975°C. The constant rates of the oxidation were determined (separately for the first and second stages of oxidation) and the energy of oxidation activation of the tested alloy was established. It was discovered that the oxidation process of the Ti-46Al-7Nb-0,7Cr-0.1Si-0.2Ni alloy develops according to the parabolic correlation, and it is only possible to determine the apparent energy of oxidation activation.
The Possibility of a Visual Analysis of the Failure of Butt Adhesive Joints Made with Different Glues
Authors: Komorek A. , Grygiel D. , Bieńczak R. , Godzimirski J. 
Published: August 2018

Abstract
The results of conducted by the authors of the article numerical analyzes, indicate the importance of normal stresses, perpendicular to the adhesive joint, during the impact destruction of block adhesive samples. This kind of stresses are responsible for the occurrence of tearing or chipping in a joint. The very significant influence of adhesion in the impact-bonded adhesive joint was the reason for testing this parameter in joints made with adhesives with different Young’s modulus. It was assumed that adhesives differing in stiffness will have different adhesive properties, which should affect the impact strength of the adhesive joints. It was also assumed that the adhesion in the joint can be assessed by analyzing the surfaces of joint damage. Cylindrical butt joints connected with various adhesives were used to carry out the tests, in which they were loaded on tear-off. The nature of tested joints damage was usually cohesive or cohesive-adhesive. The assessment of the nature of joint damage allowed to determine whether they were the result of the loss of cohesion by the adhesive (cohesive damage) or the effect of poor adhesion between the hardened joint and adherends (adhesive damage). The assessment of the nature of the destruction was carried out by three methods: visual, using an optical microscope and using an electron microscope. As a result of the carried out observations, it was found that the visual method is the least useful and not very reliable, especially in the case of transparent or low-contrast in relation to the glued material joints. The use of electron microscope allows to obtain the most reliable results, however, the possible magnification is too large and the assessment of the entire weld fracture is difficult because it does not fit in the field of observation. Observations conducted using optical microscopy at a slight magnification (5-10 times), in most cases allow to determine the nature of the destruction to a satisfactory degree, with limitations such as in the visual method.
Expert Evaluation of Consumer Properties of Probiotics Marketed in Ukraine
Authors: Chukhray Iryna , Bilushchak Halyna , Kolyasa Lubov , Tokar Olha , Datsko Andrij 
Published: August 2018

Abstract
On the basis of results of experimental evaluation by 88 doctors and 100 pharmacists, the availability of information for them on probiotics has been investigated; new sources of such information have been detected, experts’ attitude to new probiotics has been studied. In the course of administration or recommendation of probiotics, experts are, mainly, guided by standards of medical aid and by their own experience. The main favorable effects of probiotics on human organism, in respondents’ opinion, are the normalization of the content of intestinal microflora and the normalization of functioning of digestive tract of human, as well as antialergetic and immunomodeling action. It is found that the main indication for application of probiotics are the syndrome of irritation of intestine and associated with antibiotic diarrhea. The averaged estimation (in points) of medicines has been calculated according to the following parameters: effectiveness, safety, frequency of prescription. With this, the competence of the experts was taken into account. The results of the carried out experts’ estimation can be used for optimization of the system of choice of probiotics
Compressive loading experiment of non-roasted bulk oil palm kernels at varying pressing factors
Authors: Kabutey Abraham , Herak David , Mizera Cestmir , Hrabe Petr 
Published: August 2018

Abstract
Compression testing of non-roasted bulk oil palm kernels at different processing factors was performed using a universal compression testing machine and a pressing vessel witha plunger. The purpose of the research was to describe regression models of deformation, deformation energy and percentage kernel oil depending on force, speed and vessel diameter. The tested compression forces were 100, 125, 150, 175 and 200 kN, while the speeds were 5, 10, 15, 20 and 25 mm min−1. Three pressing vessels of diameter 60, 80 and 100 mm were used. Samples were compressed at an initial height of 60 mm. For varying forces and vessel diameters at a constant speed of 5 mm min−1, the values of deformation, deformation energy and percentage kernel oil ranged from 28.47±0.89 to 37.45±0.11 mm, 796±0.82 to 1795±49.01 J and 7.33±0.26 to 25.67±0.39%. At a constant force of 200 kN for different speeds and vessel diameters; the aforementioned determined parameters also ranged from 31.91±1.61 to 37.63±1.21 mm, 1012±26.76 to 1795±49.01 J and 14.66±0.42 to 24.98±1.37%. The results were statistically significant (p<0.05) or (F-ratio>F-critical), with high coefficients of determination between 0.74 and 0.99. Thus, higher force at specific speed may be needed to maximally recover kernel oil.
Pubertal anabolic androgenic steroid exposure in male rats affects levels of gonadal steroids, mating frequency, and pregnancy outcome
Authors: Mohd Mutalip Siti Syairah , Shah Aishah Mohd , Mohamad Mashani , Mani Vasudevan , Hussin Siti Nooraishah , Surindar Singh Gurmeet Kaur 
Published: August 2018

Abstract

Background
Testosterone, nandrolone, and stanozolol are among the highly consumed anabolic androgenic steroids (AASs). Although the desired effects of AAS are being achieved by the abusers, unfortunately, this leads to numerous physical and physiological side effects. The present study was designed to investigate and determine whether early pubertal exposure to AAS treatment had detrimental effects on blood testosterone and estradiol concentrations, mating behavior, and pregnancy outcome during the pubertal period in male rats.

Materials
Early pubertal rats (PND41) were given two doses (2.5 mg/kg and 5 mg/kg) each of testosterone, nandrolone, and stanozolol subcutaneously for 6 weeks. Upon completion, three rats with the highest weight were chosen from each group for mating with the females, in a ratio of one male to two females for 10 days. After 10 days, all male rats were sacrificed to obtain the testes for weight recording, and blood samples were collected for testosterone and estradiol quantitation. Pregnant females were housed separately until birth, and the number of offsprings produced was counted.

Results
The results clearly show a reduction in reproductive hormonal and behavioral parameters between testosterone and nandrolone, and testosterone and stanozolol. Stanozolol administration exhibited suppressing effects in all parameters including testicular weight deterioration, serum testosterone and estradiol reduction, low mating preferences, and declined pregnancy outcome.

Conclusions
AAS exposure during the onset of puberty results in reproductive detrimental effects, which are postulated to affect the pregnancy rate.
Wankel Engines for Unmanned Aerial Vehicles
Authors: Melnarowicz Władysław 
Published: August 2018

Abstract
The article presents the possibility of using a rotary piston engine, called the Wankel engine, to drive for unmanned aerial vehicles. It describes the principle of engine operation, its advantages and disadvantages. The article specifies the categories of drones to which these engines are dedicated. The author presents the modular Wankel engine of 5-120 hp for unmanned aerial vehicles, manufactured by Advanced Innovative Engeeniering.
Helmet-Mounted Attitude Control Algorithms of the Opto-Electronic Surveillance System for Aircraft Search and Rescue Actions
Authors: Szelmanowski Andrzej , Pazur Andrzej , Janik Paweł , Pietnoczko Bogdan 
Published: August 2018

Abstract
This article presents selected results of work concerning the errors modeling of helmet-mounted cueing systems used for guided weapon and opto-electronic surveillance systems target homing (for realizing aircraft search and rescue actions). There were described algorithms of helmet angular position determination on the basis of inertial and magnetic methods, moreover, the possibilities of their modification. On this background there were presented the authorial method of pilot’s helmet angular position determination dedicated for helmet-mounted cueing systems for fighter helicopters. The method is based on the pilot’s helmet and aircraft body linear accelerations measurements, which then are used for the current quaternion evaluation to describe the helmet position relatively to the aircraft. Simulation models were tested in Matlab-Simulink and Borland C++ computational packages for various pilot’s helmet space orientation using specialized rotation test stands.
On the characterization of Jensen m-convex polynomials
Authors: Lara Teodoro , Merentes Nelson , Quintero Roy , Rosales Edgar 
Published: August 2018

Abstract
The main objective of this research is to characterize all the real polynomial functions of degree less than the fourth which are Jensen m-convex on the set of non-negative real numbers. In the first section, it is established for that class of functions what conditions must satisfy a particular polynomial in order to be starshaped on the same set. Finally, both kinds of results are combined in order to find examples of either Jensen m-convex functions which are not starshaped or viceversa.
Preconditioning for diffusion problem with small size high resolution inclusions
Authors: Kuznetsov Yuri A. 
Published: August 2018

Abstract
In this paper, we propose and investigate a new preconditioning technique for diffusion problems with multiple small size high contrast inclusions. The inclusions partitioned into two groups. In the first group inclusions the value of diffusion coefficient can be very small, and in the inclusions of the second group it can be very large. The classical P1 finite element discretization is converted in the special algebraic saddle point system. The solution method combines elimination of the DOFs from the first group of inclusions with the Preconditioned Lanczos method with block diagonal preconditioner for the rest of the DOFs. Condition number estimates for the proposed preconditioner are given.