bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE SURGICAL TREATMENT OF SLIPPING OF THE UPPER FEMORAL EPIPHYSIS
Authors: Newman P. H. 
Published: February 2018

Simple pinning to fix the epiphysis in those patients in whom the position is acceptable is a valuable surgical procedure. It is safe and gives good results. It eliminates the danger of further displacement, promotes fusion of the epiphysial plate and allows the patient to return to full activity within one month, thus avoiding joint stiffness, muscle atrophy, osteoporosis and interference with growth at other sites. Fixation by small pins is preferable to the use of the trifin nail, the latter giving excessive trauma and predisposing to subtrochanteric fracture. Gentle replacement of the epiphysis, when loose, into an acceptable position is a valuable method of treatment. It is essential that replacement is not undertaken by force. The problem of major displacement of the epiphysis which cannot be so replaced is unsolved. Conservative treatment in this group is useless and harmful. Intra-articular osteotomy can give good results in most cases but is risky and may cause stiffening of the hip. Subtrochanteric osteotomy does not give a good anatomical result but in most cases the function of the hip is satisfactory. Slipping of the upper femoral epiphysis, however slight, should be regarded as a surgical emergency.
DIAMETRIC FRACTURES OF THE PELVIS
Authors: Dommisse G. F. 
Published: February 2018

1. The strength of the pelvic arch depends on the integrity of the anterior interpubic ligament, whose strength has been demonstrated by dissections. Once that ligament is divided the sacro-iliac ligaments offer little resistance to opening out of the pelvis. 2. The structure of the pelvis and hips is compared to an arcade formed by a central and two lateral arches. The weight of the trunk is transmitted to the lower limbs through this arcade. 3. Fractures of the pelvis are classified according to the mechanism of production. The case for anatomical reposition and internal fixation is stated, and case histories are given to illustrate the disabilities due to persistent deformity. 4. Reduction can be achieved as late as two or three weeks after injury. However, if early operation for visceral injury is necessary, there is a strong case for combining this with open reduction and fixation. In some cases the patient's general condition may preclude such procedures, but more usually the additional manipulations cause little additional operative shock and are fully justified by the subsequent increased comfort of the patient and the greater ease of nursing.
NEONATAL SCIATIC PALSY FROM INJECTION INTO THE UMBILICAL CORD
Authors: Shaw N. E. 
Published: February 2018

1. Three new cases of neonatal sciatic palsy are reported in twins. They received identical treatment after birth; in the case of the first two for identical difficulties occurring after delivery. In twins there is a greater liability to neonatal shock and so a greater incidence of umbilical injections. 2. The clinical evidence and the necropsy findings in Case 3 support the hypothesis that intra-arterial thrombosis is caused by the injection of an analeptic into the umbilical artery. 3. The clinical picture is described, with a discussion on the pathology, treatment and the reason for recovery in some cases.
EXTRA CENTRE OF OSSIFICATION FOR THE MEDIAL MALLEOLUS IN CHILDREN
Authors: Powell H. D. W. 
Published: February 2018

1. Two boys complaining of pain in the ankle were shown to have centres of separate ossification for the medial malleoli. These were present bilaterally, but discomfort was unilateral. 2. In one, followed for fifteen months, the extra centre became wholly incorporated into the normal lower tibial epiphysis. 3. in a series of 100 children between the ages of six and twelve, without any known disease or injury of the ankles, radiographs showed that 20 per cent had a separate medial malleolar centre on one side. In 13 per cent this finding was present bilaterally. In one child a separate lateral malleolar centre was also found. 4. The significance of this finding is discussed, and it is considered to be a normal variant. 5. Occasionally one of these centres may remain unfused into adult life. Attention is drawn to the possible implications of this persistence.
THE CHEMICAL BACKGROUND OF INTERVERTEBRAL DISC PROLAPSE
Authors: Mitchell P. E. G. , Hendry N. G. C. , Billewicz W. Z. 
Published: February 2018

Two groups of intervertebral discs, one normal, as obtained from the post-mortem room, the other prolapsed, as removed at operation, have been compared by chemical analysis of their principal constituents. There is a progression of chemical changes associated with the ageing of the normal disc. This shows not only the expected slight increase in collagen as age advances, but also, surprisingly, that the polysaccharide content rises to a maximum in the fourth decade, in the same way as does polysaccharide in costal cartilage. In prolapsed discs the ageing process is superseded by a different and distinctive progression, which advances, not according to age, but according to the duration of the prolapse. There is a critical level to which the polysaccharide content must apparently fall, irrespective of the normal level for the patient's age, before a prolapse occurs. Normal ageing probably consists in the breakdown of a particular polysaccharide/protein linkage, with coincident "maturation" of collagen. In the prolapsing disc multiple, and possibly different, linkages are rapidly broken down. This depolymerisation of a gel structure must be presumed to be the basis of the decreased imbibition capacity of the nucleus pulposus, and to be the source of the hydrostatic abnormalities which result in disc prolapse. In both normal and prolapsing discs the products of mucopolysaccharide breakdown appear to participate in the metabolism of collagen.
FRACTURE MECHANICS
Authors: Alms Michael 
Published: February 2018

1. Linear fractures of the shaft of the long bones are divided into four basic types: 1) transverse; 2) oblique transverse; 3) spiral; and 4) oblique. 2. The mode of production of these fractures is deduced on the grounds of simple mechanical theory: 1) transverse fractures are a result of angulation; 2) oblique transyerse are the result of angulation with axial loading; 3) spiral fractures are the result of axial twists with or without axial loading; 4) oblique fractures are the result of angulation and axial twisting in the presence of axial loading.
TRAUMATIC DISLOCATION OF THE HIP IN CHILDHOOD
Authors: Piggot J. 
Published: February 2018

1. Nine cases of traumatic dislocation of the hip in children have been reviewed. 2. There was one instance of avascular necrosis of the femoral head, which became apparent six months after injury. 3. In one case fracture of the femur on the same side led to four days' delay in recognition and treatment of the dislocation. 4. At the time of review all patients were free from symptoms.
TRAUMATIC DISLOCATION OF THE HIP WITH FRACTURE OF THE SHAFT OF THE IPSILATERAL FEMUR
Authors: Wadsworth Thomas G. 
Published: February 2018

1. A brief summary is given of the literature on patients with a dislocated hip and a fractured femur on the same side. 2. One further patient is reported, treated by closed reduction of the hip and the fracture. 3. A warning is given on the frequency with which the dislocation is not diagnosed in this double injury.
ELECTRODIAGNOSIS
Authors: Parry C. B. Wynn 
Published: February 2018

1. The results of electrodiagnostic tests reveal the level and progress of nerve lesions. 2. The findings in a myopathic lesion are: a) a normal SD curve; b) no fibrillation on the E.M.G.; c) on volition a full interference pattern-because motor units have not been lost, but only muscle fibres within the units; d) the action potentials are short in duration, polyphasic and of low amplitude; e) conduction times are normal. 3. In peripheral nerve affections these findings are evidence of denervation: a) a sluggish response to a long duration current; b) a kinked SD curve; c) fibrillation at rest on the E.M.G.; d) a reduced interference pattern of motor unit action potentials on volition; e) a preponderance of polyphasic action potentials of long and short duration; f) slowing of conduction times. 4. Evidence of reinnervation is given by: a) a kink in the SD curve; b) the appearance of a response in the muscle to nerve stimulation; c) a progressive increase in conduction velocity; d) the appearance of polyphasic action potentials on volition; e) fibrillation becoming more difficult to detect. 5. The following findings suggest a lesion of the anterior horn cell: a) difficulty in detecting fibrillation, and a relatively normal SD curve in the presence of marked wasting. (Intact axons have "mopped up" denervated fibres.) b) Marked reduction in interference pattern with ‘giant units’. c) Normal conduction velocity.
A CASE OF NEUROPATHIC ARTHRITIS CAUSED BY INDIFFERENCE TO PAIN
Authors: van der Houwen H. 
Published: February 2018

1. A twenty-five-year-old man who developed neuropathic arthritis because of indifference to pain is described. He presented at the age of thirteen with degenerative changes in the light knee with analgesia only in the right leg below the knee. 2. A painless fracture of the ulna developed non-union and was associated with a neuropathic arthritis of the elbow joint. 3. Later the other knee and the lumbo-sacral spine became affected. The analgesia became generalised with all other senses staying intact. Apart from tonic pupillary reactions and diminished corneal sensibility no other neurological signs could be found. 4. A deceased sister may also have suffered from the same condition.
CAUSES OF FAILURE AFTER REPAIR OF THE MEDIAN NERVE
Authors: Mackenzie I. G. , Woods C. G. 
Published: February 2018

1 . The clinical results in forty cases of repair of the median nerve at the wrist have been examined. Almost half were unsatisfactory. 2. The factors that may have predisposed to failure of adequate re-innervation are discussed. 3. The results might be improved by the use of radio-opaque markers for early detection of separation at the suture line, and by the use of frozen sections to determine the adequacy of resection.
REGIONAL OSTEOPOROSIS IN OSTEOLD OSTEOMA
Authors: Spence A. J. , Lloyd-Roberts G. C. 
Published: February 2018

1. Regional osteoporosis is a common finding in osteoid osteoma. It may in fact be a constant feature because it was present in all the patients reported in this paper and was suspected in others who have not been included in this report because of insufficient information. 2. Five of our six cases showed osteoporosis about the hip. Osteoporosis is more likely to be noticed in this region than in other parts of the extremities because both hips are usually radiographed on one film. We have seen several instances in which we suspected generalised osteoporosis of an extremity but Case 5 was the only one in which comparable radiographs had been taken of both feet. 3. When there is osteoporosis in the region of a joint with symptoms referred to that joint an osteoid osteoma may be the cause. The nidus may lie at some distance from the joint surfaces and may not be seen in standard radiographs of the joint (Case 4). Additional radiographs including a wider area than usual may be necessary to show the lesion, and tomography is sometimes required.
DELAYED OPERATION IN THE OPEN REDUCTION OF FRACTURES OF LONG BONES
Authors: Charnley John , Guindy Adly 
Published: February 2018

1. The findings in this series of fractures of the shaft of the femur treated by intramedullary nailing confirm the observation of Smith (1959) that the incidence of non-union is significantly diminished when operative intervention is postponed more than one week from the time of the injury. 2. The series is too small to afford conclusive proof, and it offers no explanation of the opposite findings of Smith and Sage (1957), but it indicates that this very important aspect of the operative treatment of fractures ought to be submitted to thorough investigation by many more observers.
FRACTURES OF THE FOREARM TREATED BY RIGID FIXATION
Authors: Hicks J. H. 
Published: February 2018

1. A series of fractures of the forearm has been treated by exceptionally rigid internal fixation with a special plate and screws. 2. The plate and screws are described. 3. The results of rigid fixation are found to be: i) reliability of union, and ii) good final function. 4. The lessons learned regarding the application of the plate and the after-treatment of the forearms are recounted.
THE ETIOLOGY OF CHONDROMALACIA PATELLAE
Authors: Outerbridge R. E. 
Published: February 2018

1. Chondromalacia of the patella starts most frequently on the medial facet. 2. The anatomy of the medial femoral condyle is described, including the rim at its superior border, and the different arrangement at the upper border of the lateral femoral condyle. 3. Rubbing of the medial patellar facet on the rim at the upper border of the medial femoral condyle can explain in part the etiology of chondromalacia.
RUPTURE OF THE AXILLARY ARTERY COMPLICATING ANTERIOR DISLOCATION OF THE SHOULDER
Authors: Johnston G. W. , Lowry J. H. 
Published: February 2018

1. A case is described ofcomplete rupture ofthe second part of the axillary artery complicating anterior dislocation of the shoulder in a woman aged fifty years. 2. Interesting features were that the patient was comparatively young, that the rupture was a result of the dislocation and not of the reduction, that the axillary vein remained intact, and that a satisfactory circulation returned after ligation of the artery.
STUDIES IN THE TRANSPLANTATION OF BONE, III. The Immune Responses of Lymph Notes Draining Components of Fresh Homologous Cancellous Bone and Homologous Bone Treated by Different Methods
Authors: Burwell R. Geoffrey , Gowland G. 
Published: February 2018

1. The antigenicity of cancellous bone has been investigated in ninety-seven rabbits. 2. The immune responses of lymph nodes draining fresh homografts of cancellous bone (Burwell and Gowland 1961b) has been used as a histological indicator of the antigenicity of components of fresh homologous cancellous bone and also of the antigenicity of homologous bone subjected to a variety of physical or chemical treatments. 3. The principal antigenic component of a fresh homograft of iliac cancellous bone is the nucleated cells of the red marrow. 4. Homologous marrow-free cancellous bone does not usually produce cytological evidence of an immune response in the lymph node draining the graft, unless new homograft bone formation occurs. 5. The treatment of marrow-containing cancellous bone by boiling, freezing at - 20 degrees Centigrade, freeze-drying, irradiation or by merthiolate solution impairs the transplantation antigenicity of the tissue as a homograft. 6. The immersion of cancellous bone in a glycerol-serum-Ringer solution which is then slowly cooled to - 79 degrees Centigrade, stored for one week and then rapidly thawed, allows considerable preservation of the antigenicity of the red marrow. 7. Knowledge concerning the antigenicity of fresh and treated homologous bone is discussed. 8. Evidence is presented to show that the large and medium lymphoid cell response of lymph nodes draining homografts is due principally to the T-antigens, rather than H-antigens, of the grafts. 9. The changes which occur in the first regional lymph nodes draining tissue homografts may provide another test system to assess the transplantation antigenicity of foreign tissues or extracts of foreign tissues other than bone.
DIAGNOSIS AND TREATMENT OF CONGENITAL DISLOCATION OF THE HIP JOINT IN THE NEW-BORN
Authors: von Rosen Sophus 
Published: February 2018

1. Congenital dislocation of the hip can be diagnosed clinically immediately after birth and the diagnosis confirmed radiologically by a special technique. 2. If the affected joint is reduced during the first two or three days after birth and held reduced for a period not exceeding three months, the joint will remain stable. 3. This treatment probably leads to normal development of the hip joint. 4. The cause of congenital dislocation of the hip may be laxity of the soft tissues of the joint and not a primary dysplasia of the acetabulum.
MEDULLARY NAILING FOR FRACTURE OF THE SHAFT OF THE TIBIA
Authors: Alms Michael 
Published: February 2018

1. A method of medullary nailing of fractures of the shaft of the tibia with a straight clover-leaf nail of large calibre is described. The nail is introduced, without exposure of the fracture, through the deep infrapatellar bursa. No external splint is used and the patient is usually allowed to walk as soon as the wound is healed. The technique is essentially that of Küntscher. 2. The results obtained in the first fifty patients so treated are described. The average period of absence from work for those twenty-five whose treatment was satisfactory was eleven weeks. There were no cases of sepsis or non-union; the only difficulties encountered were mechanical ones.
CHANGES IN DENSITY OF THE HUMAN FEMORAL CORTEX WITH AGE
Authors: Atkinson P. J. , Weatherell J. A. , Weidmann S. M. 
Published: February 2018

1. Discs of bone from two fixed sites on the front of the femur were taken from ninety-one necropsy subjects and the density, width and histological appearance of the cortical bone were examined. 2. Cortical thickness, and the density of the femoralcortex, decreased with increasingage of bone. 3. There was an increase in the rate of resorption of the bone cortex from both sexes after the fifth decade. 4. The difference between the density of the metaphysial cortex and that from the diaphysis increased for both sexes after the age of fifty, because of the greater metaphysial resorption. 5. There was no change in the degree of mineralisation of the cortical bone with age. The decrease in density with age is, therefore, accounted for by resorption.
CHONDROECTODERMAL DYSPLASIA
Authors: Ellis R. W. B. , Andrew J. Douglas 
Published: February 2018

1. Two cases are reported showing the syndrome of chondrodysplasia, manual polydactyly, ectodermal dysplasia affecting the teeth and nails, and congenital heart disease. 2. Particulars of thirty-eight cases are tabulated, and the features of the syndrome are discussed. 3. The syndrome is regarded as showing an autosomal recessive mode of inheritance.
THE "HALO" TRACTION APPARATUS
Authors: Thompson Harral 
Published: February 2018

1. The "halo" traction apparatus and its method of application are described in detail. 2. Its use in nine patients with subluxation or fracture-dislocation of the cervical spine, and in one patient with extensive vertebral disease, is recorded. 3. The indications for using the "halo" traction apparatus are outlined.
LUBRICATION WITHIN LIVING JOINTS
Authors: Barnett C. H. , Cobbold A. F. 
Published: February 2018

1. By the use of a device that allows movement of a human finger joint to take place uninfluenced by muscle activity, the coefficient of friction has been determined between living articular surfaces. 2. The force of friction rises as the range of movement is increased, because of the tension then developing in the ligaments and the soft tissues surrounding the joint. 3. Measurements have also been made of the forces of friction within the ankle joint of the dog and within four types of reciprocating bearings (plastic, oil-lubricated, "floating" and hydrostatic). 4. By altering the load borne by the joints and bearings it has been shown that joints resemble in their behaviour those bearings in which a film of fluid is maintained between the fixed and moving surfaces, rather than bearings depending wholly or in part on boundary lubrication. 5. It is suggested that joints normally owe their great freedom of movement to a special type of fluid film lubrication that has been termed "weeping lubrication," supplemented by "floating lubrication," though on occasions boundary conditions may prevail.
OSTEITIS PRODUCED EXPERIMENTALLY IN MICE BY THE VIRUS OF TICK-BORNE ENCEPHALITIS
Authors: Markowa Janina 
Published: February 2018

Experiments on white mice were undertaken to determine the reaction of bone to the intramedullary introduction of the virus of tick-borne encephalitis. The following conclusions were drawn. 1. The tick-borne encephalitis virus S47, when introduced intraosteally in white mice, provokes osteitis. 2. Inflammation may lead to acute necrosis of bone, preceded by marked medullary oedema and subsequent proliferation, or it may take a milder form with haemorrhagic effusion into the marrow tissue and subsequent hyperplasia of connective tissue. 3. Damage to the epiphysial and articular cartilage may ensue in the course of acute necrotic osteitis. 4. Skeletal and extra-skeletal osteogenesis is a characteristic feature of viral osteitis. 5. In radiographs in acute viral osteitis with extensive necrosis the expanded bone appears to be thickened. 6. Viruses of the S47 strain introduced intraosteally preserve their affinity for brain tissue after three passages through bone. 7. Viruses introduced into the bony tissue preserve their toxicity and are found in the bony tissue after ten days in quantities lethal for young mice when inoculated intracerebrally. 8. The tick-borne encephalitis virus S47 is pathogenic when inoculated into the marrow in white mice. 9. In osteitis of non-bacterial origin in man the possibility of viral infection should be considered.
OS INTERMETATARSEUM AND A POSSIBLE RELATIONSHIP TO HALLUX VALGUS
Authors: Henderson Robert S. 
Published: February 2018

1. A group of cases is presented in which the os intermetatarseum took the form of an intermetatarsal spur, from which (in members of one family) there arose a tendon-like structure whose distal attachment was to the lateral aspect of the proximal phalanx of the great toe. The suggestion is made that this may represent a lost first plantar interosseous muscle. 2. Another effect of the presence of an os intermetatarseum is the production of metatarsus primus varus by its action as a wedge which spreads apart the bases of the two metatarsal bones. A very small wedge may at times produce considerable deviation (Case 4), and resection of the os can result in satisfactory correction. 3. It is also felt that over-development of extensor hallucis brevis may at times contribute to the formation of hallux valgus.