bluuebunny/crossref_metadata_2025_split huggingface dataset:
The multilayer semantic network structure of community tensions
Authors: Randazzo Casey , Shugars Sarah , Acosta Rachel M. , Doerfel Marya 
Published: December 2024

IntroductionSemantic network analysis is an important tool researchers can use to untangle the knots of tension that arise as communities debate and discuss complex issues. Yet words connect not only to each other in community discourse but to larger themes or issues.MethodsIn this paper, we demonstrate the use of multilayer analysis for the study of semantic networks, helping to unravel connections within and between community tensions. In examining knotted tensions that arise in the wake of disaster, this study also spotlights how climate disasters exacerbate issues like housing equity, disproportionately affecting lower-income communities. We examine discourse across eight months of online neighborhood threads about community issues in the aftermath of Hurricane Ida. We identify core tensions related to environmental sustainability, overdevelopment, neighborhood identity preservation, and economic vitality. Our within-tension analysis reveals the community's struggle with such dilemmas, while our between-tension analysis shows the interconnectedness of these issues. Our approach highlights which stakeholders are best positioned to address specific community problems.ResultsThe findings challenge the conventional top-down disaster response narrative, proposing a theoretically informed method for employing semantic network analysis to examine community crises. Through this work, we extend organizational communication theories of knotted tensions, offering a nuanced lens to community discourse in the face of wicked problems.
Sexual decision-making: an exploratory interview study of Cambodian adolescents
Authors: Park Gloria , Yang Youngran 
Published: December 2024

IntroductionThe rate of sexual activity among adolescents is very high, with serious repercussions such as human immunodeficiency virus (HIV) and sexually transmitted diseases. Understanding the factors that influence adolescents’ engagement in sexual activity is crucial for promoting healthy sexual attitudes and behaviors in schools, sex education programs, communities, and families. This study aimed to examine the factors influencing sexual decision-making among Cambodian adolescents.MethodsIn accordance with the Standards for Reporting Qualitative Research (SRQR), this study used a descriptive qualitative methodology with individual interviews. The participants in the study were 30 Cambodian adolescents (15 males and 15 females) who were all unmarried and sexually active. They were recruited using various methods, including social networking services, and interviewed to explore their sexual decision-making processes.ResultsThe analysis revealed that the decision-making process was influenced by both internal and external factors. Internal factors included sexually explicit Internet material and arousal from sexy outfits, while external factors included foreign vs. Khmer culture, the surrounding environment including community, peers, and family, and educational advice received at school. Gender differences were noted in responses to stimuli like sexy outfits and perceptions of cultural norms.ConclusionsThis study underscores the complexity of adolescent sexual decision-making in Cambodia. It highlights the need for sex education that is not only comprehensive but also culturally sensitive, addressing the diverse influences on these adolescents. Future research should include a broader demographic group, including rural adolescents, to gain more comprehensive insights.Implications for practiceThis study uncovers how cultural norms, peers, and the media impact sexual behaviors, emphasizing the significant gender differences in these aspects. The findings shed light on the necessity of culturally sensitive and comprehensive sex education and the urgent need for tailored approaches to health promotion and education.
Three Decades of Adolescent Health: Unveiling Global Trends Across 41 Countries in Psychological and Somatic Complaints (1994–2022)
Authors: Schrijvers Karen , Cosma Alina , Potrebny Thomas , Thorsteinsson Einar , Catunda Carolina , Reiss Franziska , Hulbert Sabina , Kostičová Michaela , Melkumova Marina , Bersia Michela , Klanšček Helena Jeriček , Gaspar Tania , Dierckens Maxim 
Published: December 2024

ObjectivesThis study examined (non-)monotonic time trends in psychological and somatic complaints among adolescents, along with gender differences.MethodsRepeated cross-sectional Health Behaviour in School-aged Children (HBSC) data from 1994 to 2022 covering 15-year-old adolescents from 41 countries (N = 470,797) were analysed. Three polynomial logistic regression models (linear, quadratic, cubic) were tested for best fit, including separate analyses by gender and health complaints dimension.ResultsTime trend patterns varied by gender and health complaints dimension. Increases were found in 82.3% of cases (linear 25%, quadratic U-shaped 28.7%, cubic 28.7%), while 14% showed no clear trend, and 3.7% decreased. Boys typically showed linear increases or no clear trend over time, whereas girls generally showed cubic or U-shaped trends. Psychological complaints often displayed U-shaped or cubic patterns, whereas somatic complaints mostly showed linear increases.ConclusionPsychological and somatic complaints demonstrated diverse time trend patterns across countries, with non-monotonic patterns (U-shaped and cubic) frequently observed alongside linear increases. These findings highlight the complexity of changes within countries over three decades, suggesting that linear modelling may not effectively capture this heterogeneity.
Protective Antimicrobial Effect of the Potential Vaccine Created on the Basis of the Structure of the IgA1 Protease from Neisseria meningitidis
Authors: Prokopenko Yuri , Zinchenko Alexei , Karlinsky David , Kotelnikova Olga , Razgulyaeva Olga , Gordeeva Elena , Nokel Elena , Serova Oxana , Kaliberda Elena , Zhigis Larisa , Rumsh Lev , Smirnov Ivan 
Published: December 2024

Background/Objectives: IgA1 protease is one of the virulence factors of Neisseria meningitidis, Haemophilus influenzae and other pathogens causing bacterial meningitis. The aim of this research is to create recombinant proteins based on fragments of the mature IgA1 protease A28–P1004 from N. meningitidis serogroup B strain H44/76. These proteins are potential components of an antimeningococcal vaccine for protection against infections caused by pathogenic strains of N. meningitidis and other bacteria producing serine-type IgA1 proteases. Methods: To obtain promising antigens for creating a vaccine, we designed and obtained several recombinant proteins. These proteins consisted of single or directly connected fragments selected from various regions of the IgA1 protease A28–P1004. The choice of these fragments was based on our calculated data on the distribution of linear and conformational B-cell epitopes and MHC-II T-cell epitopes in the structure of IgA1 protease, taking into account the physicochemical properties of potential compounds and the results of a comparative analysis of the spatial structures of the original IgA1 protease and potential recombinant proteins. We studied the immunogenic and protective effects of the obtained proteins on the BALB/c mice against meningococci of serogroups A, B and C. Results: Proteins MA28–P1004-LEH6, MW140–K833-LEH6, MW329–P1004-LEH6, M(W140–H328)-(W412–D604)-(Y866–P1004)-LEH6 and M(W140–Q299)-(Y866–P1004)-LEH6 have shown the following antibody titers, 103/titer: 11 ± 1, 6 ± 2, 6 ± 1, 9 ± 1 and 22 ± 3, respectively. Also, the last two proteins have shown the best average degree of protection from N. meningitidis serogroups A, B and C, %: 62 ± 6, 63 ± 5, 67 ± 4 respectively for M(W140–H328)-(W412–D604)-(Y866–P1004)-LEH6 and 70 ± 5, 66 ± 6, 83 ± 3 respectively for M(W140–Q299)-(Y866–P1004)-LEH6. Conclusions: We selected two recombinant proteins consisting of two (M(W140–Q299)-(Y866–P1004)-LEH6) or three (M(W140–H328)-(W412–D604)-(Y866–P1004)-LEH6) linked fragments of IgA1 protease A28–P1004 as candidate active component for an antimeningococcal vaccine.
Analisis penyuluhan pendidikan kesehatan sebagai upaya meningkatkan pengetahuan dan sikap remaja tentang HIV/AIDS
Authors: Tsabitha Athiya Dwi , Wijhati Ellyda Rizki 
Published: December 2024

Latar Belakang: Remaja merupakan kelompok beresiko untuk tertular HIV/AIDS karena rasa ingin tahu yang tinggi membuat mereka mencari banyak informasi sehingga mudah terbawa arus untuk melakukan hal-hal beresiko seperti pergaulan bebas dan menggunakan narkoba. Tujuan penelitian ini untuk menganalisis pendidikan kesehatan sebagai upaya meningkatkan pengetahuan remaja tentang HIV/AIDS.Metode: Penelitian ini menggunakan pre eksperimen desain dengan pendekatan One-Group Pretest-Posttest. Sampel dalam penelitian ini berjumlah 71 siswa SMP, teknik sampling Purposive sampling. Alat pengumpulan data menggunakan kuesioner survey demografi kesehatan indonesia (SDKI) 2017.Hasil: Analisis bivariat menunjukkan bahwa ada pengaruh pendidikan kesehatan terhadap kenaikan pengetahuan p value = 0,000, ada pengaruh pendidikan kesehatan terhadap sikap p value = 0,000.Kesimpulan: Ada pengaruh pendidikan kesehatan tentang HIV/AIDS terhadap pengetahuan dan sikap remaja dalam pencegahan HIV/AIDS.
Hubungan dukungan keluarga dan self care dengan kualitas hidup pasien diabetes mellitus tipe 2
Authors: Dewi Rosliana , Suherman Reni , Oktaviani Yeni , Melinda Fera , Budiana Johan 
Published: December 2024

Latar Belakang: International Diabetes Federation memprediksi kasus diabetes akan mengalami peningkatan dari 537 juta jiwa di tahun 2021, menjadi 643 juta jiwa di tahun 2030. Tujuan penelitian ini untuk mengetahui hubungan dukungan keluarga dan Self Care dengan kualitas hidup pasien diabetes mellitus tipe II di Desa Sukaresmi Wilayah Kerja Puskesmas Cisaat Kabupaten Sukabumi.Metode: Desain penelitian menggunakan korelasional dengan pendekatan cross sectional. Populasi dan sampel dalam penelitian ini yaitu seluruh pasien diabetes mellitus tipe II di Desa Sukaresmi Wilayah Kerja Puskesmas Cisaat Kabupaten Sukabumi, sebanyak 95 responden dengan teknik total sampling. Analisis hipotesis menggunakan chi-square.Hasil: Hasil penelitian menunjukan sebagian besar dukungan keluarga mendukung, Self Care baik, dan kualitas hidup baik. Analisis bivariat menunjukan terdapat hubungan dukungan keluarga dengan kualitas hidup (p-value 0,031) dan Self Care dengan kualitas hidup di dapatkan p-value (0,001).Kesimpulan: Hasil dapat disimpulkan bahwa terdapat hubungan dukungan keluarga dan Self Care dengan kualitas hidup pasien diabetes mellitus tipe II. Diharapkan Puskesmas Cisaat dapat meningkatkan program home care dan edukasi kepada pasien dan keluarganya.
Раскрывая новые парадигмы: обзор патогенетических механизмов и перспективных методов лечения множественной миеломы
Authors: Д.А. Чебыкина , Д.В. Моторин , Н.Ю. Семенова , Е.В. Мотыко , А.Н. Кириенко , Д.В. Кустова , А.Ю. Кувшинов , С.В. Сидоркевич , И.С. Мартынкевич 
Published: December 2024

Множественная миелома остается сложным гематологическим заболеванием, требующим постоянного изучения его биологии и поиска новых терапевтических подходов. Несмотря на внедрение в клиническую практику различных классов лекарственных средств, таких как иммуномодулирующие препараты, ингибиторы протеасом и моноклональные антитела, множественная миелома по-прежнему включена в группу хронических неизлечимых заболеваний. Цель настоящей работы – предоставить всесторонний обзор патогенетических механизмов, лежащих в основе лекарственной резистентности, и рассмотреть возможные опции персонализированной терапии. Путем подробного анализа данных клинических исследований последних лет оценить эффективность и возможность применения в клинической практике развивающихся методов лечения.
Multiple myeloma (MM) remains a complex hematological disease that requires constant study of its biology and the search for new therapeutic approaches. Despite the introduction into clinical practice of various classes of drugs, such as immunomodulatory drugs, proteasome inhibitors and monoclonal antibodies, MM is still included in the group of chronic incurable diseases. The purpose of this work is to provide a comprehensive overview of the pathogenetic mechanisms underlying drug resistance and to consider possible options for personalized therapy. Through a detailed analysis of data from clinical trials in recent years, to evaluate the effectiveness and feasibility of developing treatment methods in clinical practice.
PENGARUH SUHU EKSTRAKSI IKAN GABUS (Channa striata) TERHADAP KANDUNGAN ALBUMIN DAN TINGKAT KESUKAAN UNTUK MINUMAN KESEHATAN
Authors: Maulid Deden Yusman , Syaban Rafli , Abrian Satriya , Pangestika Widya , Siregar Arpan Nasri , Arumsari Kusuma , Nusaibah Nusaibah , Andayani Tri Rahayu , Herry Herry , Yuniarti Endah 
Published: December 2024

Snakehead (Channa striata) is widely found in open water such as rivers and swamps in Indonesia. Snakehead contains albumin which is useful for accelerating the wound healing process. The purpose of this study was to determine the best extraction temperature that can produce the highest albumin content and is preffered by panelist when applied to healthy drinks. This study consisted of three treatments, namely the extraction temperature of 60°C, 70°C, and 80°C. The parameters observed were the yield of snakehead extract, protein content of snakehead, albumin content, and the level of preference (Hedonic). The yield of snakehead extract refers to the method developed by Asikin, 2017. Protein content was tested using the Kjeldahl method, albumin content was tested using the BCG (Brom Cresil Green) method. The preference level test was based on the method developed by Rahayu (2017). The highest yield of snakehead extract was obtained at a temperature of 80°C, namely 54,6%. The highest protein content was found in the 60°C temperature treatment, which was 3,62%. The highest albumin content was found at 80°C temperature treatment, which was 0,04 g/dl. The results of the hedonic test show that there is no difference sgnificantly between treatments with the limit value is still preferred (5).
Keyword: albumin, snakehead, healthy drinks, sensory

Ikan gabus (Channa striata) banyak terdapat di perairan terbuka seperti sungai dan rawa yang ada di Indonesia. ikan gabus memiliki kandungan albumin yang bermanfaat untuk mempercepat proses penyembuhan luka. Tujuan dari penelitian ini adalah untuk menentukan suhu ekstraksi terbaik yang dapat menghasilkan kandungan albumin yang paling tinggi serta disukai oleh panelis ketika diaplikasikan ke minuman kesehatan. Penelitian ini terdiri dari tiga perlakuan yaitu suhu ekstraksi 60°C; 70°C; dan 80°C. Parameter yang diamati adalah rendemen ekstrak ikan gabus, kandungan protein ikan gabus, kandungan albumin, serta tingkat kesukaan (Hedonik). Rendemen ekstrak ikan gabus mengacu kepada metode yang dikembangkan Asikin, 2017. Kandungan protein di uji menggunakan metode Kjeldahl, kandungan albumin di uji dengan metode BCG (Brom Cresil Green), uji tingkat kesukaan mengacu kepada metode yang dikembangkan Rahayu (2017). Hasil rendemen ekstrak ikan gabus tertinggi didapatkan pada suhu 80°C yaitu 54,6%. Kandungan protein tertinggi terdapat pada perlakuan suhu 60°C yaitu 3,62%. Kandungan albumin tertinggi terdapat pada perlakuan suhu 80°C yaitu 0,04 g/dl. Hasil uji hedonik terhadap minuman kesehatan menunjukan bahwa tidak ada perbedaan yang signifikan antar perlakuan dengan batasan nilai masih disukai (5).
Kata kunci: ekstrak albumin, ikan gabus, minuman kesehatan, sensori
PENGARUH PERENDAMAN JERUK NIPIS (Citrus aurantifolia) TERHADAP KARAKTERISTIK FISIK DAN ORGANOLEPTIK DARI TEPUNG KEPALA UDANG WINDU (Penaeus monodon)
Authors: Ika Ikawati , Hasanah Rafitah , Mismawati Andi 
Published: December 2024

Tiger shrimp heads have a fairly high fat content of 13%, so a process of minimizing fat is needed to prevent rancidity. Soaking lime solution has the potential to reduce fat levels. The purpose of this study was to find out how the physical and organoleptic characteristics of tiger shrimp head meal with different lime solution immersion. The treatment used is W0 (control), W1 (5%), W2 (10%) and W3 (15%). This study showed that soaking lime solution had a significant effect on tiger shrimp head flour yield, color test, and organoleptic. The average yield value of 20.6%-22.8% indicates that the higher the concentration of lime solution, the lower the yield produced. The color test results show a noticeable effect as the concentration of lime solution increases. The average color test results for brightness (L*) values are 57.78%-61.87%, reddish (a*) 10.51-16.90, yellowish (b*) 20.12-25.49 and white degree 48.45%-52.28%. The results of sensory tests showed a real influence on appearance, namely somewhat clean, less clean type-specific colors, type-specific colors (7-9), but no real effect on odor, namely the smell of shrimp flour was strong enough (7) and foreign objects were absent (9). The best hedonic test results in the W1 treatment (5%) were consumer acceptance rates at appearance 7.7 (very like), smell 7.13 (like), taste 6.83 (like) and texture 7.37 (like).
Kata kunci: Color, Flour, Organoleptic, Shrimp head.

Kepala udang windu memiliki kadar lemak yang cukup tinggi yaitu 13%, sehingga diperlukan proses meminimumkan lemak untuk mencegah ketengikan. Perendaman larutan jeruk nipis berpotensi untuk menurunkan kadar lemak. Tujuan Penelitian ini untuk mengetahui bagaimana karakteristik fisik dan organoleptik tepung kepala udang windu dengan perendaman larutan jeruk nipis yang berbeda. Perlakuan yang digunakan yaitu W0 (kontrol), W1 (5%), W2 (10%) dan W3 (15%). Penelitian ini menunjukkan perendaman larutan jeruk nipis berpengaruh nyata pada rendemen, uji warna, dan organoleptik tepung kepala udang windu. Hasil rata-rata nilai rendemen 20,6%-22,8% menunjukkan semakin tinggi konsentrasi larutan jeruk nipis, semakin rendah rendemen yang dihasilkan. Hasil uji warna menunjukkan adanya pengaruh nyata seiring meningkatnya konsentrasi larutan jeruk nipis. Hasil rata-rata uji warna untuk nilai kecerahan (L*) 57,78%-61,87%, kemerahan (a*) 10,51-16,90, kekuningan (b*) 20,12- 25,49 dan derajat putih 48,45%-52,28%. Hasil uji sensori menunjukkan adanya pengaruh nyata pada kenampakan yaitu agak bersih, warna kurang spesifik jenis-bersih, warna spesifik jenis (7-9), namun tidak berpengaruh nyata terhadap bau yaitu bau tepung udang cukup kuat (7) dan benda asing yaitu tidak ada (9). Hasil uji hedonik terbaik pada perlakuan W1 (5%) yaitu tingkat penerimaan konsumen pada kenampakan 7,7 (sangat suka), bau 7,13 (suka), rasa 6,83 (suka) dan tekstur 7,37 (suka).
Kata kunci: Jeruk nipis, Kepala udang, Organoleptik, Tepung, Warna
CEMARAN LOGAM BERAT (Cd, Pb, Hg, Sn), KAPANG DAN BAKTERI (Salmonella, Staphylococcus aureus, Escherichia coli) PADA STIK IKAN LAYANG
Authors: Aristawati Anita Treisya , Finarti  , Dewanto Didit Kustantio , Mohamad Syahril  
Published: December 2024

Layang fish (Decapterus sp), which contains high nutritional value, is very good for preventing stunting. Fish sticks are a snack that many people like. Testing for metal and biological contamination is very important to ensure the safety and quality of sticks. Food contaminated with heavy metals or bacteria can cause poisoning and disease. The aim of this research is to determine heavy metal contamination (Cd, Pb, Hg, Sn) and bacteria (Mould, Salmonella, Staphylococcus aureus, and Escherichia coli) in Layang fish sticks. The ingredients used are Layang fish meat, tapioca flour, wheat flour, eggs, garlic and salt. Testing for metal contamination of Layang fish sticks using the ICP-MS method. Making sticks with the addition of fish is a food processing innovation with the aim of increasing nutritional value. The formulation used in this research was flying fish meat at 0% (D1), 10% (D2), 20% (D3), 30% (D4), and 40% (D5) of the amount of tapioca flour used three times. test. The research results showed that the heavy metals mercury, tin and cadmium were not found, but the heavy metal lead was found with values ​​of 0.09 to 0.14. This value does not exceed the threshold of SNI 0.2 - 2 mg/kg and BPOM 2022, namely 0.3 mg/kg. Likewise, in microbiological tests, Layang fish sticks are safe from mold, Salmonella bacteria, Staphylococcus aureus and Escherichia coli.
Kata kunci: heavy metal, bacteria, laying fish, fish stick

Ikan layang (Decapterus sp) yang mengandung nilai gizi tinggi, sangat baik untuk mencegah stunting. Stik ikan merupakan cemilan yang banyak disukai. Pengujian cemaran logam dan biologi sangat penting untuk menjamin keamanan dan mutu stik. Makanan yang tercemar logam berat atau bakteri dapat menyebabkan keracunan dan penyakit. Tujuan penelitian ini, untuk mengetahui cemaran logam berat (Cd, Pb, Hg, Sn) dan bakteri (Kapang, Salmonella,Staphylococcus aureus, dan Escherichia coli) pada stik ikan layang. Bahan yang digunakan adalah daging ikan layang, tepung tapioka, tepung terigu, telur, bawang putih, dan garam. Pengujian cemaran logam stik ikan layang menggunakan metode ICP-MS. Pembuatan stik dengan penambahan ikan merupakan inovasi pengolahan pangan dengan tujuan meningkatkan nilai gizi. Formulasi yang digunakan dalam penelitian ini yaitu daging ikan layang sebesar 0% (D1), 10% (D2), 20% (D3), 30% (D4), dan 40% (D5) dari jumlah tepung tapioka yang digunakan dengan tiga kali ulangan. Hasil penelitian menunjukkan bahwa tidak ditemukan logam berat merkuri, timah, dan kadmium, namun ditemukan logam berat timbal dengan nilai 0.09 sampai 0.14. Nilai ini tidak melebihi ambang batas dari SNI 0.2 - 2 mg/kg dan BPOM tahun 2022 yaitu 0,3 mg/kg. Demikian pula dalam uji mikrobiologi, stik ikan layang aman dari Kapang, bakteri Salmonella, Staphylococcus aureus, dan Escherichia coli.
Kata kunci: logam berat, bakteri, ikan laying, stik ikan
Tindak Tutur Direktif Berbahasa Mentawai Dalam Acara Nusa Mentawai Radio Sasaraina
Authors: Fitrianti Eva , Yefrizon Yefrizon 
Published: December 2024

Artikel ini bertujuan untuk menganalisis dan mendeskripiskan bentuk dan fungsi tindak tutur direktif dalam acara Nusa Mentawai radio Sasaraina. Sumber data adalah tuturan penyiar dan pendengar acara Nusa Mentawai radio Sasaraina. Data dikumpulkan Melalui teknik simak, teknik rekam, teknik catat, dan teknik pustaka. Validasi data dilakukan dengan triangulasi sumber dan teori. Analisis data memanfaatkan kondensasi, tampilan, dan penyimpulan data. Kajian ini menghasilkan bentuk tindak tutur direktif kelompok permintaan, kelompok pertanyaan, kelompok persyaratan, kelompok larangan, kelompok pengizinan, dan kelompok nasihat. Fungsi tindak tutur direktif yaitu fungsi kompetitif, menyenangkan, dan bertentangan. Implikasi hasil kajian ini dapat dimanfaatkan bagi anggota masyarakat secara luas untuk memilih tuturan direktif dalam berkomunikasi sesuai dengan konteks tuturan.