bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contrasting responses of intertidal microphytobenthos and phytoplankton biomass and taxonomic composition to the nutrient loads in the Jiulong River Estuary
Authors: Xie Yuyuan , Wang Lei , Liu Xin , Li Xin , Wang Yuanyong , Huang Bangqin 
Published: December 2018

SUMMARYMicrophytobenthos (MPB) and phytoplankton are important primary producers in the estuarial ecosystem, and their functions are critical to the ecosystem's biodiversity and environmental safety. The aim of this study was to compare the response of MPB and phytoplankton to the nutrient loads in a eutrophic estuary, which has seldom been studied. We used high‐performance liquid chromatography (HPLC) and CHEMTAX software to examine the biomass and taxonomic composition of both MPB and phytoplankton at Da‐yu Island (DYI) and Ji‐yu Island (JYI) in the Jiulong River Estuary from July 2010 to March 2012. The results showed that MPB chlorophyll a was low in the summer and high in the winter at both DYI and JYI, indicating a unimodal pattern. However, the phytoplankton chlorophyll a showed a mirrored pattern. Diatoms were the dominant class in both benthic and pelagic environments. Although redundancy analysis indicated that the effects of different environmental factors could not be easily separated, it is likely that phosphate and temperature were the most important factors regulating the seasonal patterns of MPB and phytoplankton diatoms, respectively. MPB and phytoplankton cyanobacteria was co‐limited by salinity and temperature. The high N/P ratio and low phosphate favored chlorophytes and cyanobacteria. Our study demonstrates the use of HPLC and CHEMTAX in an integrated survey of the spatial and temporal distribution patterns of MPB and phytoplankton in an estuarial ecosystem. The contrasting responses of MPB and phytoplankton to nutrient loads indicate the critical role of MPB in subtropical estuarial ecosystem function. The relationship between nutrients and MPB may indicate a significant contribution to carbon and nutrient cycling.
Improving gender outcomes in social security retirement systems
Authors: Brimblecombe Simon , McClanahan Shea 
Published: December 2018

AbstractAssessing whether retirement systems meet their varying objectives requires analysing outcomes across different categories of beneficiaries with different working, financial, demographic, and family situations. Policymakers should therefore assess systems on the distribution of outcomes rather than average outcomes.Much has been written about the gender inequalities inherent in labour markets and how these are reflected and reproduced in pension systems, and there is growing evidence that recent reforms have exacerbated these trends. Recent research has turned to the policy measures available to policymakers to forestall or reverse these trends, but this literature tends to overlook important administrative measures that have the potential to reduce inequalities in access that could improve pension outcomes for women within the current policy framework. This paper examines the main issues surrounding gender inequality in retirement outcomes; explores the implications of recent reform trends in light of the differential outcomes for women, including policy options to mitigate the negative impacts; and concludes with a review of key administrative measures, including streamlining affiliation procedures, improving information, and simplifying payment of contributions and receipt of benefits and better compliance of employers.
Who benefits from partial tax coordination?
Authors: Han Yutao , Wan Xi 
Published: December 2018

AbstractIn this paper, we investigate whether partial tax coordination is beneficial to countries within and outside a tax union, in which countries are supposed to compete in taxes and infrastructure. Our results demonstrate that a subgroup of countries agreeing on a common tax rate can harm both member and nonmember states. This is in contrast to the classical findings that partial tax harmonisation is Pareto improving. When a minimum tax rate is imposed within a tax union, we demonstrate that it does not necessarily improve the welfare of the member countries. Moreover, both the high‐tax and low‐tax countries can be worse off. This conclusion is at odds with the classical result that a high‐tax country benefits from the imposition of a lower tax bound.
Effect of ranolazine on glycaemia in adults with and without diabetes: a meta-analysis of randomised controlled trials
Authors: Teoh Ik Hur , Banerjee Moulinath 
Published: December 2018

BackgroundRanolazine is an antianginal drug reported to have hypoglycaemic effects.ObjectivesTo assess the effect of ranolazine versus placebo on glycaemic control for adults with and without diabetes.MethodsA systematic search of seven databases was conducted to identify all randomised controlled trials that compared the effect of ranolazine versus placebo on haemoglobin A1c (HbA1c) and/or fasting plasma glucose (FPG) and/or incidence of hypoglycaemia. We used mean differences in HbA1c and FPG to express intervention effect estimates and analysed the data with random-effects model for meta-analyses using Revman 5.3.ResultsWe identified seven trials including 6543 subjects to assess the effect of ranolazine on HbA1c and/or FPG. A separate trial that included 944 subjects was included to assess the effect of ranolazine on hypoglycaemia. The change in HbA1c for all patients was −0.36% (95% CI −0.57% to −0.15%; p=0.0004, I2=78%). In patients with diabetes, the change in HbA1c was −0.41% (95% CI −0.58% to −0.25%; p<0.00001, I2=65%). There was no significant difference in FPG between ranolazine and placebo groups (−2.58 mmol/L, 95% CI −7.02 to 1.85; p=0.25; I2=49%) or incidence of hypoglycaemia between ranolazine and placebo groups (OR 1.70, 95% CI 0.89 to 3.26; p=0.61, I2=0%).ConclusionsOur meta-analytic findings support the fact that ranolazine improves HbA1c without increasing the risk of hypoglycaemia. It therefore has a potential of having an additional benefit of improving glycaemic control in patients with chronic stable angina and diabetes.
Exercise-based cardiac rehabilitation improves exercise capacity and health-related quality of life in people with atrial fibrillation: a systematic review and meta-analysis of randomised and non-randomised trials
Authors: Smart Neil A , King Nicola , Lambert Jeffrey D , Pearson Melissa J , Campbell John L , Risom Signe S , Taylor Rod S 
Published: December 2018

ObjectiveThe aim of this study was to undertake a contemporary review of the impact of exercise-based cardiac rehabilitation (CR) targeted at patients with atrial fibrillation (AF).MethodsWe conducted searches of PubMED, EMBASE and the Cochrane Library of Controlled Trials (up until 30 November 2017) using key terms related to exercise-based CR and AF. Randomised and non-randomised controlled trials were included if they compared the effects of an exercise-based CR intervention to a no exercise or usual care control group. Meta-analyses of outcomes were conducted where appropriate.ResultsThe nine randomised trials included 959 (483 exercise-based CR vs 476 controls) patients with various types of AF. Compared with control, pooled analysis showed no difference in all-cause mortality (risk ratio (RR) 1.08, 95% CI 0.77 to 1.53, p=0.64) following exercise-based CR. However, there were improvements in health-related quality of life (mean SF-36 mental component score (MCS): 4.00, 95% CI 0.26 to 7.74; p=0.04 and mean SF-36 physical component score: 1.82, 95% CI 0.06 to 3.59; p=0.04) and exercise capacity (mean peak VO2: 1.59 ml/kg/min, 95% CI 0.11 to 3.08; p=0.04; mean 6 min walk test: 46.9 m, 95% CI 26.4 to 67.4; p<0.001) with exercise-based CR. Improvements were also seen in AF symptom burden and markers of cardiac function.ConclusionsExercise capacity, cardiac function, symptom burden and health-related quality of life were improved with exercise-based CR in the short term (up to 6 months) targeted at patients with AF. However, high-quality multicentre randomised trials are needed to clarify the impact of exercise-based CR on key patient and health system outcomes (including health-related quality of life, mortality, hospitalisation and costs) and how these effects may vary across AF subtypes.
КАРДІОЛОГІЧНІ АСПЕКТИ МЕРЕЖЕВОЇ МЕДИЦИНИ
Authors: Mintser O. P. , Zalisky V. M. 
Published: December 2018

У статті подано короткий огляд основних публікацій із мережевої медицині та застосування комплексного мережевого аналізу білкових взаємодій у вивченні захворювань людини. З огляду на функціональні взаємозалежності між молекулярними компонентами в клітині людини, захворювання рідко є наслідком аномалії в одному гені, але відображає комплексні аномалії внутрішньоклітинної мережі. Нові інструменти мережевої медицини пропонують платформу для системного вивчення не лише молекулярної складності конкретного захворювання (що веде до ідентифікації модулів і шляхів захворювання), але також і молекулярних відносин між явно вираженими (патогенними) фенотипами.
Постулюється, що, виявляючи нові гени захворювань, необхідно визначати біологічну значимість пов'язаних із захворюванням мутацій, виявлених у результаті досліджень геному в цілому, та повного секвенування геному, а також виявлення мішеней і біомаркерів складних захворювань.
Робиться також висновок, що мережева медицина й онтологія знань мають багато спільного як у стратегії створення, так і в технологіях використання. Проте завдання багатовимірного моделювання сьогодні переважно виконуються в стратегії «онтологія знань». Те ж можна сказати й про освіту, де онтологічні рішення більш популярні.
Увагу приділено питанням мережевого взаємозв'язку різних кардіологічних захворювань на молекулярному та фенотипічному рівнях. Багато захворювань серця розглядаються за допомогою комплексних клінічних фенотипів, що формуються в результаті інтегративного впливу на молекулярному (інтерактомному), генетичному (геномному) та екологічному (метаболомному) рівнях.
National Policy for Regional Development: Historical Evidence from Appalachian Highways
Authors: Jaworski Taylor , Kitchens Carl T. 
Published: December 2018

Abstract
How effective are policies aimed at integrating isolated regions? We answer this question in the context of a highway system in one of the poorest regions in the United States. With construction starting in 1965, the Appalachian Development Highway System (ADHS) ultimately consisted of over 2,500 high-grade road miles. We use a simple model of interregional trade to motivate our empirical analysis, which quantifies the relationship between market access and income. We then calibrate the model to evaluate the aggregate impact of the ADHS and compare this with alternative counterfactual proposals. We find that removing the ADHS would have reduced total income by $53.7 billion in the United States, with $22 billion of the losses in Appalachian counties. Our findings highlight the potential aggregate benefits of transportation infrastructure policies and suggest that leakage outside the targeted area may be substantial.
Czeska koncepcja zdrady jako element mitu monachijskiego
Authors: Kubok Beata 
Published: December 2018

The Czech concept of betrayal as an element of the Munich mythThis article explores the cultural significance of the “Munich myth”, focusing on the concept of “Western betrayal” and its connotations associated with the idea of destiny and sacrifice. It also examines how the myth influenced the formation of Czech national identity, especially during and shortly after the Second World War. Opening with an analysis of a poem by František Halas written in the midst of the Munich Conference, it also reviews a number of writings which increased the popularity of the ideas of betrayal and sacrifice and, as a result, have made them synonymous with the “Czech fate”: excerpts from the memoirs of Zdeněk Štĕpánek and Edvard Beneš, essays by Karel Kosík and Milan Kundera, and Bedřich Fučík’s literary criticism. The article concludes with a discussion of the key findings of the book Mnichovský komplex (The Munich Complex) by Jan Tesař, a polemic study discrediting and deconstructing the myth of the “Munich betrayal”. Czeska koncepcja zdrady jako element mitu monachijskiegoArtykuł dotyczy fenomenów kulturowych zawartych w micie monachijskim, szczególnie takich, jak koncepcja zdrady i powiązane z nią konotacje (figura ofiary, losu, teatralizacja życia społecznego). Przedstawia także proces formowania się wojennej oraz powojennej czeskiej tożsamości narodowej pod wpływem tego mitu. W artykule poddano analizie wiersze Františka Halasa z okresu wydarzeń monachijskich, a także te fragmenty wspomnień (Zdenĕk Štĕpánek, Edvard Beneš), eseistyki (Karel Kosík, Milan Kundera) i krytyki literackiej (Bedřich Fučík), które przyczyniły się do rozpowszechnienia koncepcji zdrady i ofiary jako czynnika konstytuującego „czeski los”. Artykuł kończy prezentacja najważniejszych tez zawartych w książce pt. Monachijski kompleks autorstwa Jana Tesařa o charakterze polemicznym i dekonstrukcyjnym wobec mitu „zdrady monachijskiej”.
The usage and meaning of "mentioned" ("wspomniany") and "described" ("opisany") metatext markers in Polish scientific texts
Authors: Czoska Agnieszka 
Published: December 2018

The usage and meaning of mentioned (wspomniany) and described (opisany) metatext markers in Polish scientific textsMetatext markers (MMs) are defined as expressions used in a text to inform readers of its structure or relations between its elements (Fraser, 1999; Goldman & Rakestraw, 2000; Schiffrin, 1988). In this paper the usage of two MMs "mentioned" ("wspomniany") and "described" ("opisany") in scientific texts is described and the relation between their meaning and usage is analysed. In Study 1, the frequency, scope and direction of the MM is analysed in a corpus of peer-reviewed scientific texts in Polish. In Experiment 2, participants decided whether to use the aforementioned MMs to fill gaps in short scientific texts. The results of both experiments suggest that while the meaning of an MM may influence its usage, this relation may be affected by the size of the whole text. Użycie i znaczenie operatorów metatekstowych wspomniany i opisany w tekstach naukowych po polskuOperatory metatekstowe (OM) to wyrażenia informujące czytelnika o strukturze tekstu, w którym zostały umieszczone, oraz o relacjach pomiędzy jego elementami (Fraser, 1999; Goldman & Rakestraw, 2000; Schiffrin, 1988). W poniższej pracy zostało opisane użycie dwóch OM wspomniany i opisany w tekstach naukowych, przeanalizowano także relację pomiędzy ich znaczeniem i używaniem. W badaniu 1 zostały przeanalizowane częstość użycia, zakres i ukierunkowanie OM w tekstach naukowych pisanych po polsku. W badaniu 2 czytelnicy decydowali o tym, czy umieścić dodatkowy OM w krótkim tekście naukowym. Wyniku obydwu badań wskazują, że znaczenie OM może wpływać na sposób jego używania, ale wpływ ten zmienia się wraz z wielkością tekstu.
A Diagnostic-Predictive Assessment of Winter Precipitation over the Laurentian Great Lakes: Effects of ENSO and Other Teleconnections
Authors: Fu Wang , Steinschneider Scott 
Published: December 2018

Abstract
This study examines the primary atmospheric controls over winter precipitation variability in the Great Lakes basin and the potential for seasonal prediction. We employ partial least squares (PLS) regression to identify the primary modes of joint variability between winter precipitation over each of the Great Lakes and concurrent anomalies in midlevel atmospheric flow. We find that the first identified pattern (PLS1) is related to El Niño–Southern Oscillation (ENSO), while the other patterns represent unique anomalies in atmospheric flow that govern precipitation gradients over the basin, with limited seasonal predictability. Nonlinearities are found in the relationship between a sea surface temperature (SST)-based index for ENSO and PLS1 with respect to the phase, strength, and type of ENSO event. An examination of the ENSO-related propagating wave train that drives variability of PLS1 precipitation reveals that seasonally lagged tropical Pacific convection, as measured by remotely sensed outgoing longwave radiation (OLR), is more strongly and linearly related to Great Lakes winter precipitation than SST-based ENSO indices. Cross-validated linear regressions based on October OLR signals explain 20%–32% of the out-of-sample precipitation variability in the Great Lakes basin. We conclude with a deeper assessment of the underlying relationship between patterns of OLR anomalies in the western equatorial Pacific and Great Lakes winter precipitation. Results show that precipitation response to El Niño is similar regardless of OLR intensity in the tropical Pacific, but for La Niña events, the precipitation response is stronger under weak tropical OLR anomalies. The potential for further improvements in ENSO-based seasonal forecasts are discussed.
Evaluation of a Simplified Risk Stratification Twice-Daily Aspirin Protocol for Venous Thromboembolism Prophylaxis After Total Joint Replacement
Authors: Ng Candy , Zavala Sarah , Davis Elissa S. , Adams William , Pinzur Michael S. 
Published: December 2018

Objective To determine using a simplified risk-stratified protocol to select candidates for aspirin therapy have similar death and postoperative complications as universal warfarin therapy in patients undergoing total joint replacement (TJR). Methods Retrospective cohort study comparing 30-day postoperative outcomes 6 months before and after the implementation of the aspirin protocol (January 1, 2015) in patients undergoing TJR. The control group was comprised of patients using warfarin for VTE prophylaxis. The protocol group included patients who used aspirin 325 mg twice-daily or warfarin if deemed high thrombotic risk or aspirin intolerant by the criteria set forth by the aspirin protocol. Results This study included 449 patients. No difference was found in the rates of 30-day postoperative bleeding, VTE, death, composite end point of VTE and death, and length of stay between the control and the protocol groups (all P > .05). Thirty-day postoperative surgical site infections (SSIs; 5.8% vs 1.2%; P = .02) and return to operative room (OR; 3.9% vs 0.4%; P = .03) were less frequent in the protocol group. Conclusion A simplified risk-stratified protocol used to choose patients for aspirin 325 mg twice-daily therapy is safe and effective in patients undergoing TJR, and SSI and return to OR rates may be lower when compared to universal warfarin therapy.
Vacuum-Assisted Wound Closure and Permanent Onlay Mesh–Mediated Fascial Traction: A Novel Technique for the Prevention of Incisional Hernia after Open Abdomen Therapy Including Results From a Retrospective Case Series
Authors: Petersson P. , Montgomery A. , Petersson U. 
Published: December 2018

Background and Aims: Incisional hernia development is a frequent long-term sequel after open abdomen treatment. This report describes a novel technique, the vacuum-assisted wound closure and permanent onlay mesh–mediated fascial traction for temporary and final closure of the open abdomen, with the intention to decrease incisional hernia rates. Primary aim was to evaluate incisional hernia development and secondary aims to describe short-term complications and patient-reported outcome. Materials and Methods: The basics of the technique is an onlay mesh, applied early during open abdomen treatment by suturing to the fascia in two rows with a 3- to 4-cm overlap from the midline incision, used for traction and kept for reinforced permanent closure. A retrospective case series, including chart review, evaluation of computed tomography/ultrasound images, and an out-patient clinical examination were performed. The patients were asked to answer a modified version of the ventral hernia pain questionnaire. Results: A total of 11 patients were treated with vacuum-assisted wound closure and permanent onlay mesh–mediated fascial traction with median follow-up of 467 days. Fascial closure rate was 100% and 30 day mortality 0%. Two of nine patients, eligible for incisional hernia follow-up, developed a hernia. Neither of the hernias were symptomatic nor clinically detectable. Six of 10 patients eligible for short-term follow-up had a prolonged wound-healing time exceeding 3 weeks. One of seven patients eligible for patient-reported outcome have had pain during the last week. Conclusion: The vacuum-assisted wound closure and permanent onlay mesh–mediated fascial traction is a promising new technique for open abdomen treatment and reinforced fascial closure. The results of the first 11 patients treated with this technique show a low incisional hernia rate with manageable short-term wound complications and few patient-reported disadvantages.
A Nationwide Follow-up Survey on the Effectiveness of an Implemented Neuromuscular Training Program to Reduce Acute Knee Injuries in Soccer Players
Authors: Åman Malin , Larsén Karin , Forssblad Magnus , Näsmark Annica , Waldén Markus , Hägglund Martin 
Published: December 2018

Background: A cruciate ligament (CL) injury is a severe injury in soccer. Neuromuscular training programs have a well-documented preventive effect, but there are few studies on the effectiveness of such a program at a national level. The Swedish Knee Control Program (KCP) was found to be effective in preventing CL injuries in youth female soccer players. The KCP was implemented nationwide in Sweden in 2010. Purpose: To evaluate the effectiveness of the Swedish KCP in reducing acute knee injuries in soccer players at a nationwide level. Study Design: Descriptive epidemiology study. Methods: All licensed soccer players in Sweden are covered by the same insurance company. Using this insurance database, around 17,500 acute knee injuries that were reported to the insurance company between 2006 and 2015 were included in the study. By matching the number of licensed soccer players with the number of reported injuries each year, the annual incidence of knee and CL injuries was able to be calculated. To evaluate the spread of the KCP nationally, a questionnaire was sent to all 24 Swedish district football associations (FAs) with questions regarding KCP education. The number of downloads of the KCP mobile application (app) was obtained. Results: The incidence of CL injuries decreased during the study period for both male (from 2.9 to 2.4 per 1000 player-years) and female players (from 4.9 to 3.9 per 1000 player-years). The overall incidence of knee injuries decreased in both male (from 5.6 to 4.6 per 1000 player-years) and female players (from 8.7 to 6.4 per 1000 player-years). Comparing before and after the nationwide implementation of the KCP, there was a decrease in the incidence of CL injuries by 6% (rate ratio [RR], 0.94 [95% CI, 0.89-0.98]) in male players and 13% (RR, 0.87 [95% CI, 0.81-0.92]) in female players and a decrease in the incidence of knee injuries by 8% (RR, 0.92 [95% CI, 0.89-0.96]) and 21% (RR, 0.79 [95% CI, 0.75-0.83]), respectively ( P < .01 for all). This trend corresponded to a reduction of approximately 100 CL injuries each year in Sweden. A total of 21 of 24 district FAs held organized KCP educational courses during the study period. The percentage of district FAs holding KCP courses was between 46% and 79% each year. There were 101,236 downloads of the KCP app. Conclusion: The KCP can be considered partially implemented nationwide, and the incidence of knee and CL injuries has decreased in both sexes at a nationwide level.