bluuebunny/crossref_metadata_2025_split huggingface dataset:
Screening for potential antidiabetes and antioxidant activities of selected plants from East Kalimantan, Indonesia
Authors: RAMADHAN RICO , KRISTANTI ALFINDA NOVI , AMIRTA RUDIANTO , KUSUMA IRAWAN WIJAYA , PHUWAPRAISIRISAN PREECHA , HAQIQI MUHAMMAD TAUFIQ , SAPARWADI SAPARWADI 
Published: August 2019

Abstract. Ramadhan R, Kristanti AN, Amirta R, Kusuma IW, Phuwapraisirisan P, Haqiqi MT, Saparwadi. 2019. Screening for potential antidiabetes and antioxidant activities of selected plants from East Kalimantan, Indonesia. Biodiversitas 20: 1820-1826. Ten selected plants in this study have been used traditionally in West Kutai, East Kalimantan as medicinal plants. This study aimed to screen and evaluate the in vitro antidiabetic and antioxidant activity of methanol extracts of selected plants from East Kalimantan. The antidiabetic activity was carried out by α-glucosidase inhibitory activity with maltose and sucrose as substrates while antioxidant activity was determined by free radicals scavenging activity against DPPH, ABTS and Nitric Oxide (NO). The results showed that Garcinia riedeliana extract had strong inhibitory activity with an IC50 value of 0.04 mg/mL followed by Shorea laevis, Pternandra azurea and Bridelia tomentosa with IC50 values of 0.12; 0.15 and 0.16 mg/mL in maltose respectively, while quercetin as positive control had an IC50 value of 0.08 mg/mL. G.riedeliana extract also showed good α-glucosidase inhibitory activity with an IC50 value of 0.23 mg/mL in sucrose as substrate. The results on antioxidant activity showed that all extracts have IC50 value against free radicals DPPH, ABTS, and nitric oxide. The most active extract as α-glucosidase inhibitory activity and antioxidant activity was G. riedeliana extract. These findings provide the scientific evidence that one species of medicinal plants from East Kalimantan might be potential as an antioxidant and α-glucosidase inhibitor.
Optimization of manganese bioleaching activity and molecular characterization of indigenous heterotrophic bacteria isolated from the sulfuric area
Authors: PRASIDYA DENAYA ANDRYA , WILOPO WAHYU , WARMADA I WAYAN , RETNANINGRUM ENDAH 
Published: August 2019

Abstract. Prasidya DA, Wilopo W, Warmada IW, Retnaningrum E. 2019. Optimization of manganese bioleaching activity and molecular characterization of indigenous heterotrophic bacteria isolated from the sulfuric area. Biodiversitas 20: 1904-1909. The present research evaluated the manganese bioleaching potency of a heterotrophic bacteria KB3B1. This bacterial strain has been isolated from sulfuric area located at Ungaran, Middle of Java, Indonesia using modified 9K medium by adding of several organic nutrients. The manganese bioleaching activities of the strain was analysed by applying of varying glycine concentrations (0, 5, 10, 15 mg mL-1) with pyrolusite pulp densities of 0.02 g cm-3 on a rotary shaker at 180 rpm for 18 days incubation. Several parameters, including the growth of bacteria, pH values, the concentration of soluble manganese and cyanide, were investigated at the interval of 3 days. Molecular characteristics of the strain were further analyzed based on 16S rDNA gene sequences. After 15 days, the maximum yield of manganese 16.6% was achieved under the addition of 10 mg mL-1 glycine. This maximum extract obtained was followed by the maximum bacterial growth, pH, and cyanide product of the strain. Phylogenetic analysis showed that the strain was closely related with Bacillus niacini EP89. Besides, the average frequencies of guanine and cytosine (G+C) of the strain was in same range as that of the reference bacteria in the GenBank and Bergey's Manual Systematics of Bacteria.
Emotion Regulation in Context: Social Connectedness Moderates Concurrent and Prospective Associations With Depressive Symptoms
Authors: Marroquín Brett , De Rutte Jennifer , May Casey L. , Wisco Blair E. 
Published: August 2019

Introduction: Emotion regulation in healthy functioning and in depression is typically examined as an intrapersonal phenomenon, but growing evidence suggests social factors affect individuals' strategy use and effectiveness. We examined whether the role of emotion regulation in depression—concurrently and over four weeks—depends on social connectedness, predicting that higher social connectedness would dilute effects of one's own strategy use regardless of specific strategy. Methods: Young adult participants (n = 187) completed measures of perceived social connectedness, depressive symptoms, two avoidant emotion regulation strategies (ruminative brooding and experiential avoidance), and two approach-oriented strategies (positive reappraisal and planning), and depressive symptoms again four weeks later (n = 166). Results: Cross-sectional associations of emotion regulation with symptoms were moderated by social connectedness: effects of both avoidant and approach strategies were weaker among more connected individuals. Prospectively, social connectedness moderated effects of approach strategies, but not avoidant strategies. Among more socially connected individuals, using approach strategies—which are typically adaptive—was associated with higher symptoms over time. Discussion: Results partially replicate previous research and support the role of social factors as important contexts of intraper-sonal emotion regulation and dysregulation in depression. Findings suggest that social resources can dilute intrapersonal effects regardless of strategy type—more in the shorter term than in the longer term—and can even lead seemingly adaptive strategies to backfire over time. Implications for research integrating emotion regulation, relationships, and depressive psychopathology are discussed.
Knock-In Rat Lines with Cre Recombinase at the Dopamine D1 and Adenosine 2a Receptor Loci
Authors: Pettibone Jeffrey R. , Yu Jai Y. , Derman Rifka C. , Faust Thomas W. , Hughes Elizabeth D. , Filipiak Wanda E. , Saunders Thomas L. , Ferrario Carrie R. , Berke Joshua D. 
Published: August 2019

AbstractGenetically modified mice have become standard tools in neuroscience research. Our understanding of the basal ganglia in particular has been greatly assisted by BAC mutants with selective transgene expression in striatal neurons forming the direct or indirect pathways. However, for more sophisticated behavioral tasks and larger intracranial implants, rat models are preferred. Furthermore, BAC lines can show variable expression patterns depending upon genomic insertion site. We therefore used CRISPR/Cas9 to generate two novel knock-in rat lines specifically encoding Cre recombinase immediately after the dopamine D1 receptor (Drd1a) or adenosine 2a receptor (Adora2a) loci. Here, we validate these lines usingin situhybridization and viral vector mediated transfection to demonstrate selective, functional Cre expression in the striatal direct and indirect pathways, respectively. We used whole-genome sequencing to confirm the lack of off-target effects and established that both rat lines have normal locomotor activity and learning in simple instrumental and Pavlovian tasks. We expect these new D1-Cre and A2a-Cre rat lines will be widely used to study both normal brain functions and neurological and psychiatric pathophysiology.
Selection of Material for Facing Drive Drum of Belt Conveyor
Authors: Hrydziushka D. V. , Brуzhevich A. V. , Piskun E. V. 
Published: August 2019

It is known that conveyor operates in chemically aggressive and abrasive environments; for this reason the drive drum of belt conveyor wears out rather rapidly. It is noted that the lining of the conveyor drum increases coefficient of friction between the conveyor drum and the conveyor belt, reduces the belt wear rate, and also protects against corrosion and abrasive wear. The plot of the PU-60 polyurethane wear rate as function of load when rolling on steel is presented. It is noted that increasing the load increases the strength of adhesive junction between steel and polyurethane rollers; friction wear causes fatigue failure of surface layers of the materials. Besides, the plot of the PU-80 polyurethane wear rate as function of load when rolling on steel is presented. The plot of the polyurethanes wear rate as function of hardness of polyurethane is presented, which shows that the lowest wear rate is demonstrated by the hardest polyurethane, PU-80. The bar chart of static friction coefficient for PU-60 and PU-80 polyurethanes demonstrates that the optimal material for lining the drive drum of a conveyor belt is PU-80. The plot of the rubber wear rate as function of load at a speed of 1 m/s is presented. The plot shows that the wear rate increases with increasing the load. This is due to the effect of two factors: growing contact deformations of the surface layer of the rubber and increasing the contact area of mating parts. It is noted that IRP-1347 rubber is less susceptible to wear than "REMAGRIP" rubber. This allows using IRP-1347 rubber in aggressive environments. The bar chart of static friction coefficient for the rubber presented in the paper shows that the investigated IRP-1347 and REMAGRIP rubber grades have the required value of static friction coefficient for use as lining material for the drive drum. The plot of the wear rate as function of the rubber hardness and as function of the polyurethane hardness is presented. In practice, it is proved that the best material for lining the drive drum is PU-80.
Experimental Studies of Effect of Shearer Auger Operating Device Effective Width on Effectiveness of Loading Process
Authors: Shabaev O. E. , Zinchenko P. P. , Meznikov A. V. 
Published: August 2019

Intensification of coal mining from mine seams of 0.55–1.20 m thick requires increasing efficiency of loose coal loading that may be achieved by selecting the optimal parameters of auger operating device of a shearer. The most reliable way to determine effect of the auger parameters on the energy parameters of the shearer operation is experimental research in actual operating conditions. As the subjects of the research, we selected up-to-date UKD400 and UKD200-500 shearers, operating in representative conditions of the Krasny Partizan mine of SE SVERDLOVANTRATSIT and Ternovskaya mine of DTEK PAVLOGRADUGOL PJSC. An adaptive method for specific mining operating conditions is proposed for determining the specific energy consumption of the shearers on material disruption and loading for thin seams in actual operating conditions based on fixing the values of currents of the cutting drive motors. Based on processing of the experimental data, an indicative dependence of the power for rock mass loading on the feed rate and the effective width of the operating device is determined. Increasing the auger effective width results in increasing the loading power and specific energy consumption. At the same time, the higher the shearer feed rate, the greater the growth of the loading power and specific energy consumption. This is due to the beginning of the process of loose rock mass circulation, and the larger the auger effective width, the more intensive the circulation process, and at the lower feed rate of the shearer the process starts. A method is proposed for selecting the auger optimum effective width based on the criteria of minimum specific energy consumption and maximum commercial productivity.
Antibacterial Activity of DMSO Extracts of Selected Plants Against Antibiotic Resistant Clinical Isolates
Authors: SARAL Ayşegül , KARDİL Uğur , ÖZAD DÜZGÜN Azer 
Published: August 2019

In this study, we aimed to find out new herbal materials
that are able to inhibit the growth of the P.
aeruginosa and E.coli clinical isolates
that has antibiotic resistance. Clinical isolates used in this research are E. coli (n=1) and P.aeruginosa (n=1). Antibiotic susceptibility profiles of E. coli and P. aeruginosa were determined using e-test. Plants were collected
in Trabzon region of Turkey are Calendula officinalis, Hypericum perforatum and Glycyrrhiza glabra. DMSO were used as
solvent and solid-liquid extraction was employed. Micro-dilution method was
preferred fo the determination of the minimum inhibitory concentration (MIC). MIC
results were obtained through observation of turbidities. According to E-test
results, while P. aeruginosa was
resistant to piperacillin, piperacillin/tazobactam, meropenem and ceftazidime, E. coli was resistant to piperacillin,
cefotaxime and ceftazidime. DMSO extract of Calendula
officinalis showed very strong activity against PA1 with the best MIC (5
mg/mL). DMSO extract of three plant had
lower MIC values (5-10 mg/ml) for EC1 and PA1 than ampicillin. In future
studies antibacterial activity of different solvents extracts of these plants
and other plants against antibiotic resistant clinical isolates will be
examined. Natural products from plants are promising in fighting with
antibiotic-resistant bacteria.
Determination of Antioxidant and Antimicrobial Activities of Some Medicinal Plants Grown in Şırnak Region of Turkey
Authors: CEYLAN Şule , YARAR Resul , CAMADAN Yasemin , SARAL Özlem , ÖZŞEN Özge 
Published: August 2019

In this study, fruits and leaves of non-wood forest
products such as leaves and fruits of Pistachio (Pistacia vera L.), Celtis
(Celtis aetnensis), Terebinth (Pistacia terebinthus L.), Hawthorn (Crataegus monogyna), Sumac (Rhus Coriaria L.), Almond (Prunus dulcis), Bitter Almond (Amygdalus Amara), and Fennel (Foeniculum Vulgare) which are used for medical purposes in the village of
Akkoyunlu in Şırnak were investigated. Several analyzes have been used to
determine antioxidant activity of herbal products. Flavonoids
and total phenolics ingredients of elected herbs were examined in the present
study. CUPRAC (Cupric Reducing Antioxidant Capacity) and FRAP (Ferric Reducing
Antioxidant Power) analyzes were utilized for measurement of antioxidant
capacity. In addition, antimicrobial capacity was determined by Minimum
Inhibitory Concentration (MIC) technique for each sample.

According
to the antioxidant results determined, among the samples examined fruit of the
sumac (Rhus
Coriaria L.) plant has the best
antioxidant activity in almost all applied antioxidant analyzes. On the other hand,
fruit of almond (Prunus dulcis) was found
to show low antioxidant activity
in almost all analyzes.
Generalizations of n-ideals of Commutative Rings
Authors: YETKİN ÇELİKEL Ece 
Published: August 2019

Let be a
commutative ring with identity and denotes
the set of all ideals of . We will concerned in this study
mainly with the generalizations of -ideals in commutative rings via a function . Properties of this class of ideals
will investigated in detail.
Serbest Metabelyen Lie Cebirlerinin Direkt Toplamlarının Test Elemanları
Authors: ESKAL Cennet , EKİCİ Naime 
Published: August 2019

M_{n_{i}}, rankı n_{i} olan serbest metabelyen Lie cebiri ve M, i=1,2,...,m için M_{n_{i}} cebirlerinin direkt toplamı olsun. Bu
çalışmada M nin bir test elemanına sahip olması için gerek
ve yeter koşulun her i için n_{i}=2 olduğu ispatlanmıştır. Ayrıca u=u_{1}+u_{2}+...+u_{m}\in M olmak üzere " u nun bir test elemanı olması için gerek ve
yeter koşul i=1,2,...,m için u_{i}\in M_{2}' ve {u_{1}, u_{2},..., u_{m}} kümesinin
bağımsız olmasıdır" sonucu elde
edilmiştir.
Yeni 5-(Dietilamino)-2-[((2-merkapto-1H-benzo[d]imidazol-5-il)imino)metil]fenol Bileşiğinin Yapısal, Elektronik ve Spektroskopik Özelliklerinin İncelenmesi
Authors: MEDETALİBEYOĞLU Hilal , KARDAŞ Faruk , BEYTUR Murat , AKYILDIRIM Onur 
Published: August 2019

Bu makalede, yeni 5-(dietilamino)-2-[((2-merkapto-1H-benzo[d]imidazol-5-il)imino)metil]fenol bileşiğinin yapısal
parametreleri (dihedral açıları, bağ uzunlukları ve bağ açıları), HOMO (en
yüksek dolu moleküler orbital) ve LUMO (en düşük boş moleküler orbital)
enerjileri, titreşim frekansları, termodinamik ve elektronik özellikleri
(termal kapasite, dönme sabitleri, entropi, toplam enerji, elektronegativite,
elektron ilgisi, kimyasal yumuşaklık
ve sertlik), Mulliken atomik yükleri ve 13C-1H NMR
kimyasal kayma verileri Gaussian09W programı kullanılarak hesaplanmıştır. Molekülün
spektroskopik ve geometrik parametreleri yoğunluk fonksiyoneli metodu
(B3LYP/B3PW91) ve Hartree-Fock (HF)
metodu kullanılarak 6-311++G(d,p) baz seti ile gaz fazında temel halde
hesaplamalar gerçekleştirilmiştir. Bununla birlikte infrared spektroskopisi
ve 13C-1H NMR kimyasal kayma değerleri deneysel
değerler ile karşılaştırılmıştır.
Domates Ekstraktının Saccharomyces cerevisiae’de Oluşturulan Krom Hasarına Karşı Koruyucu Etkisi
Authors: ASLAN Abdullah , BEYAZ Seda , GÖK Özlem 
Published: August 2019

Bu çalışmada 4 grup oluşturulmuştur. Gruplar: (i) Kontrol grubu; (ii)
Domates ekstraktı grubu (DE); (iii) Krom grubu; (iv) DE + Krom grubu. S. cerevisiae kültürleri 1
saat, 3 saat, 5 saat ve 24 saat boyunca 30 °C'de geliştirildi. Hücre gelişimi
ve lipit peroksidasyonu MDA (malondialdehit) analizleri spektrofotometre ile
belirlendi. Total protein değişiklikleri SDS-PAGE elektroforezi ile tespit
edildi ve Bradford metodu ile hesaplandı. Elde edilen sonuçlara göre; krom grubu ile kıyaslandığında hücre
gelişimi ve total
protein sentezi, DE’ de (1, 3, 5 ve 24 saat)
artarken, MDA seviyesinde azalış göstermiştir. Sonuç olarak DE’nin S. cerevisiae kültüründe oksidatif hasarı azaltmasının yanı sıra, hücre büyümesini ve
total protein sentezini teşvik edici bir role sahip olduğunu söyleyebiliriz
Bir Nanoakışkanın Farklı pH Değerlerindeki Isı Transfer Katsayılarının Belirlenmesi ve Karar Ağacı Algoritması ile Modellenmesi
Authors: DAS Mehmet , DEMİRPOLAT Ahmet Beyzade 
Published: August 2019

Boru içi akışlarda
ısı transferini artırarak enerjiyi daha faydalı bir şekilde kullanabilmek
önemlidir. Çünkü teknolojik gelişmelerle birlikte sanayi sektöründe artan bir
enerji talebi mevcuttur. Bu nedenle araştırmacılar son yıllarda yeni nesil ısı
transfer akışkanları üzerinde çalışmaktadırlar. Çalışmamızda, CuO (bakır oksit)
nanopartikül üretimi yapıldı. Üretilen malzemenin nano malzeme özelliğine sahip
olduğunu gösteren taramalı elektron mikroskopu (TEM) görüntü analizi ve X ışını
kırınım yöntemi analizi (XRD) analizleri
yapılmıştır. CuO nanopartiküllerle
beraber saf su, etanol ve etilen glikol malzemeleri kullanılarak bir
nanoakışkan elde edilmiştir. Elde edilen nanoakışkanın farklı pH değerlerinde
ısı transfer katsayıları belirlenmiştir. Ayrıca farklı pH değerlerinde ısı
transfer katsayıları ile Reynolds sayısı arasındaki ilişkiyi incelenmiştir.
Yapılan deneysel çalışmalarda Re değeri 887 ve 2290 iken ısı transfer katsayısı
değeri sırasıyla 349,821 (W/m²°C) ve 374,253 (W/m²°C) olarak hesaplanmıştır. pH
değeri 7.84 ve 9.95 iken ısı transfer katsayısı değeri sırasıyla 349,821
(W/m²°C) ve 374,253 (W/m²°C) olarak hesaplanmıştır. Deney çalışmaları ile
hesaplanan ısı transfer katsayıları için karar ağacı (KA) algoritmaları
kullanılarak tahminsel modeller elde edilmiştir. Elde edilen modellerin
geçerliliğini belirlemek için, ortalama karesel hata (MSE), kök ortalama
karesel hata (RMSE), ortalama mutlak yüzde hata (MAPE) analizleri yapılmıştır.
Sonuç olarak pH değerleri arttıkça da nanoakışkanın ısı transfer katsayısı
değerinin azaldığı gözlemlenmiştir. Farklı Reynolds değerlerinde elde edilen
nanoakışkanın ısı transfer katsayısı, Saf suya ait ısı transfer katsayından
yaklaşım %13.3 oranında daha yüksek olduğu belirtilmiştir. Hesaplamalı zeka yöntemi olan KA algoritmasının
nanoakışkanların termofiziksel özelliğini tahminlemesinde 0.891 MAPE değerine
göre başarılı olduğu gösterilmiştir.
Biçimlendirmeyi Yapay Sinir Ağları Kullanarak 58,60,61,62,63,64Ni İzotopları için (p, ), (n, ) ve (,) Reaksiyon Tesir Kesiti Hesaplamaları ve Optimizasyonu
Authors: ÇAPALI Veli 
Published: August 2019

Bu çalışmada; nükleer reaksiyon tesir kesiti verilerinin hesaplanması için
yapay sinir ağlarının kullanımı incelenmiştir. Uygulama kriterleri yaklaştırma
oranı, deneysel veriler, değerlendirilmiş veriler ve teorik nükleer reaksiyon
modelleri ile gerçekleştirilen hesaplama değerleri kullanılarak belirlenmiştir.
58,60,61,62,63,64Ni izotopları için (n, g), (p, g) ve (a, g) reaksiyon tesir kesitleri yapay
sinir ağları kullanılarak hesaplanmıştır. Sonuçlar, bu yeni tekniğin bazı
nükleer reaksiyonların hesaplanmasındaki etkinliğini ve uygulanabilirliğini
göstermektedir.Gelişen teknolojiye ve sanayileşmeye bağlı olarak enerjiye duyulan ihtiyacın giderilmesi yönünde nükleer enerjiye ve nükleer enerji reaktörlerine yönelim olmuştur. Nükleer enerjiye olan bu yönelim ve ilgi, nükleer teknolojisinde ve fisyon reaksiyonu temelinde yeni reaktör sistemlerinin tasarlanmasına yol açmıştır
DETERMINANTS OF BRAND PREFERENCE OF COMMERCIAL THREE WHEELER PASSENGER AUTO RICKSHAW DRIVERS IN ADAMA CITY, ETHIOPIA
Authors: Shaikh Mohd Arif , Prasad U Devi , Devi Pagadala Sugandha 
Published: August 2019

Purpose of the study: The aim of this study is to find out the factors that influence drivers of three wheeler auto rickshaw in their brand preference towards different brands of commercial three wheeler passenger auto rickshaw in Adama City, Ethiopia Methodology: Primary data was collected from 500 auto drivers using a pilot tested questionnaire consisting of 40 questions. Cronbach’s alpha measure was used to test constructs reliability and in order to identify brand preference, exploratory factor analysis and parallel analysis was conducted. Main Findings: PCA revealed that there are 11 factors whose Eigen values are above 1. A look at scree plot indicated that there is a need to reconsider the number of factors to be used for further analysis. This decision was supported by Parallel analysis and 8 relevant factors identified. This 8 component solution explained 64.25 % of the variance. Applications of this study: Identification of determinants of brand preference can be used by three wheeler passenger auto manufacturers and distributors in Ethiopia Novelty/Originality of this study: There is no study conducted on drivers brand preference of three wheeler passenger auto rickshaws in Ethiopia.
THE MODERATING ROLE OF JOB EMBEDDEDNESS ON THE EFFECT OF ORGANISATIONAL JUSTICE AND ORGANISATIONAL LEARNING CULTURE ON TURNOVER INTENTION: A CONCEPTUAL REVIEW
Authors: Saoula Oussama , Fareed Muhammad , Hamid Rawiyah Abd , Esmail Abu Al-Rejal Hussein Mohammed , Ismail Saiful Azizi 
Published: August 2019

Purpose: Employee’s turnover has been investigated by many researchers as an organisations’ negative outcome. The organizations that facing high rates of turnover should examine the fundamental reasons that cause employees’ turnover in order to reach real solutions to this problem. For that, they should ask a dynamic question, why some employees stay and some leave?
Methodology: The reasons may seem difficult and consistent to the preferences and necessities of the employees. From another aspect, the majority of research in the context of turnover intention have been conducted in the western contexts, therefore it is worthwhile to encourage more studies in non-western settings to discover new understandings related to the problem.
Results: Malaysia is considered as one of the developing countries that is having high turnover of employees in many sectors. Consequently, this study proposed a research framework to examine the relationship between organisational justice (OJ)’s three dimensions (Distributive justice, procedural justice and interactional justice), organisational learning culture (OLC) and turnover intention (TI). Furthermore this study recommended the moderating role of Job embeddedness (JE) in this relationship. Hence, the suggested research framework will contribute to the body of knowledge through providing new insights.