bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compact [O iii] Emission-line Regions (“Green Seeds”) in Hα Emitters at Cosmic Noon from JWST Observations
Authors: Chen Nuo , Motohara Kentaro , Spitler Lee , Malkan Matthew A. 
Published: February 2025

Abstract
We present a rest-frame optical, spatially resolved analysis of more than 100 Hα emitters (HAEs) at z ∼ 2.2 in the ZFOURGE-CDFS field using NIRCam imaging from the JWST Advanced Deep Extragalactic Survey. The ultradeep, high-resolution data give us maps of the resolved emission-line regions of HAEs with stellar mass ranging from 108
M
⊙ to 1010
M
⊙. An [O iii] emission-line map of each HAE is created from the flux excess in the F150W filter, leading to the discovery of a population of kiloparsec-scale compact emission-line regions (“Green Seeds”) with high equivalent widths (EW). We obtain a sample of 128 Green Seeds from 68 HAEs with rest-frame EW[O III] > 200 Å. Moreover, 17 of them have extremely large EW[O III] > 1000 Å, suggesting the possible Lyman continuum leakage from these emission-line regions. Embedded within the host galaxy, many Green Seeds correspond to UV star-forming clumps and H ii regions, indicating elevated starburst activity in them, with specific star formation rates several times higher than that of the host galaxy. Based on theoretical frameworks, Green Seeds are expected to be formed through gravitational disk instability and/or galaxy mergers. Considering the stellar masses of Green Seeds, we speculate that high-mass Green Seeds may migrate toward the galactic center to build the central bulge, while low-mass Green Seeds are easily disrupted and short lived. Besides, we propose that some Green Seeds could be the progenitors of globular clusters or ultracompact dwarf galaxies observed in the local Universe.
Lo «católico» de la Proclamación Católica de Gaspar Sala
Authors: Gloël Matthias 
Published: February 2025

El presente estudio analiza la Proclamación Católica de Gaspar Sala bajo el enfoque católico que da nombre a la obra, un aspecto hasta ahora descuidado por los estudios de esta obra y de la revuelta catalana en general. En consecuencia, se realiza un análisis basado en el concepto de monarquía católica, identidad que toma la monarquía a principios del siglo XVII. Tras aclarar dicho concepto y sus diferencias con el título de rey católico se analiza la obra en tres partes. La primera consiste en una contraposición de los catalanes como vasallos católicos con los soldados del rey como vasallos sacrílegos. La segunda contrapone los mismos catalanes como buenos vasallos con los malos ministros a cargo del gobierno de la monarquía. Finalmente, la tercera parte es un resumen de la historia de Cataluña como monarquía electiva. Se concluye que para las tres partes es necesario tomar como trasfondo el concepto de monarquía católica para una interpretación adecuada de la obra.
Valentim Fernandes et ses compilations de récits de voyages (1502-1510)
Authors: Loureiro Rui Manuel 
Published: February 2025

Valentim Fernandes, aussi connu sous le nom de Valentinus Moravus, s’est installé au Portugal au début des années 1490. Peu de temps après, il est déjà étroitement lié à la maison royale portugaise et est devenu le plus important imprimeur en activité du Portugal. En plus d’avoir publié des ouvrages à caractère religieux, juridique et humaniste, il a réuni deux importants recueils de récits de voyage. L’un fut imprimé en 1502 à Lisbonne sous le titre Marco Paulo ; l’autre, resté manuscrit et finalement intégré à la bibliothèque de Konrad Peutinger, membre de l’élite politique germanique, est connu sous le nom de Codex Valentim Fernandes. Le présent article vise à mettre au jour et à faire connaître ces deux compilations, ainsi que le contexte de leur constitution.
L’accomplissement pratique d’une « conscience sensorielle » lors de vidéo consultations médicales
Authors: Grosjean Sylvie , Cherba Maria 
Published: February 2025

L’article examine l’accomplissement du « travail sensoriel » lors de consultations médicales à distance. L’étude repose sur des vidéos de consultations simulées et des entretiens d’auto-confrontation avec des médecins. Nous analysons la manière dont les médecins, grâce à une attention distribuée et des stratégies multimodales (gestes, cadrages, verbalisations), adaptent leurs pratiques cliniques pour « sentir à distance ». Les résultats montrent qu’une conscience sensorielle, essentielle pour poser un diagnostic, intègre des dimensions interactives (création d’affordances et co-production de prises visuelles) et réflexives (sensibilité aux indices sensoriels). Cette étude offre des pistes pour la formation des professionnel·les de santé, soulignant l’importance de la réflexivité sur l’activité clinique médiée par la technologie.
Mobilités et immobilités des populations insulaires bretonnes : quand le quotidien influence les choix résidentiels
Authors: Audard Frédéric , Jézéquel Pauline , David Laurence 
Published: February 2025

Les îles, marquées par une forme d’éloignement et une faible diversité économique, ont une dynamique démographique unique. Leur relation avec le continent évolue, et les récents changements démographiques modifient profondément leurs rapports territoriaux, exacerbant leur marginalité géographique et sociale.Cet article a pour objectif d’étudier le rapport entre mobilité quotidienne et mobilité résidentielle dans ce contexte insulaire complexe. Nous avons porté notre analyse dans un premier temps sur les mobilités résidentielles des populations vers les contextes insulaires français métropolitains, dans un deuxième temps sur les spécificités de la mobilité quotidienne des îliens, pour finalement étudier les liens qui sous-tendent la relation entre mobilité quotidienne et mobilité résidentielle.Ces différentes analyses font émerger une double logique de contrainte : la mobilité quotidienne, très conditionnée par la situation géographique des îles, conduit, pour certaines catégories de population, à des mobilités résidentielles tournées vers des métropoles et des grands ports. Ainsi, pour des logiques d’emplois, d’études et de modification du cadre familial, on assiste à des migrations vers le continent, posant parfois de vraies difficultés de retour.
Les systèmes de transport pour penser l’insularité : regards croisés entre la Nouvelle-Calédonie et le Vanuatu
Authors: Duverger Anne-Clémence 
Published: February 2025

Pour certains géographes, isolement et insularité sont liés ; de ce fait, les systèmes de transport doivent pallier les effets de l’insularité. Dans ces conditions, les systèmes de transport peuvent-ils ouvrir une nouvelle voie pour appréhender l’insularité ? Comment peuvent-ils permettre d’approcher celle-ci ? L’objectif de cet article est de jeter les bases d’un indice d’insularité considérant les systèmes de transport inter-îles pour les espaces archipélagiques. Afin d’alimenter la réflexion, la Nouvelle-Calédonie et le Vanuatu sont comparés. Nous nous appuierons sur les travaux relatifs à l’insularité pour saisir l’essence de ce concept et un retour sur la notion « d’île » permettra de saisir les liens entretenus entre insularité et systèmes de transport. Puis, nous mettrons en évidence un biais majeur des indices développés dans les recherches antérieures relatives aux espaces insulaires : ces dernières abordent généralement les îles du point de vue de l’isolement. C’est pourquoi nous développons des indices permettant d’apprécier l’ouverture des espaces insulaires. Enfin, une réflexion est menée sur la mesure de l’insularité, via une approche quantitative, puis en se basant sur les pratiques de déplacement des insulaires et enfin en analysant un espace insulaire particulier (Maré en Nouvelle-Calédonie) lors d’une période de « fermeture » de l’île.
CO-OCCURRENCE OF JAK2/CALR-POSITIVE MYELOPROLIFERATIVE DISORDER AND BCR-ABL-POSITIVE CHRONIC MYELOGENOUS LEUKAEMIA TREATED WITH COMBINATION OF TYROSINE KINASE INHIBITORS AND RUXOLITINIB.
Authors: Paciaroni Katia , Campagna Selenia , Villiva' Nicoletta , Maffini Enrico , Celesti Francesca , Tordi Attilio , Lombardi Mariangela , Dragonetti Giulia , Caravita di Toritto Tommaso 
Published: February 2025

The concomitant presence of BCR-Abl1 and JAK2/CALR mutations in Myeloproliferative neoplasms (MPNs) is rare. The clinical presentation of Chronic Myelogenous Leukemia (CML) and Ph-negative MPN may vary, but CML seems to play a dominant role, so patients usually receive treatment with tyrosine kinase inhibitor (TKI) only. The second Ph-negative MPN becomes evident under the selective pressure of the TK.I.
The migration of South African emergency care practitioners to the Middle East
Authors: Mthombeni Siyanda I. , Vincent-Lambert Craig 
Published: February 2025

Background: The loss of healthcare professionals because of migration remains a challenge for low- and middle-income countries. South African Emergency Care Practitioners (ECPs) are no exception with many choosing to leave South Africa (SA) to work in the Middle East (ME).Aim: To investigate and describe the push and pull factors that are influencing ECPs to leave SA and work in the ME.Setting: The study took place in the ME in an online setting.Methods: A prospective mixed-method sequential design was adopted that made use of a purposively designed, pre-piloted, online questionnaire followed by a number of one-on-one interviews with a purposefully selected sample of participants to explore push and pull factors that influenced their decision to leave SA to work in the ME.Results: The increased cost of living, low salaries, poor and unsafe working environments, and being undervalued by management in SA were the main push factors that emerged. Better pay, improved safety and security and a better quality of life in the ME were identified as core pull factors that are drawing South African ECPs to the ME.Conclusion: To stem the ongoing exodus of ECPs, significant work has to be done to improve local salaries, working conditions and the overall job satisfaction experienced by operational ECPs in SA.Contribution: Understanding why ECPs are leaving the country, and in particular why they choose the ME as their employment destination can assist Emergency Medical Services (EMS) managers to implement measures that aid in the retention of these highly skilled healthcare professionals.
Barriers to organisational resilience to climate hazards: A case study of Chikwawa, Malawi
Authors: Khendlo Japhet N. , Beeharry Roodheer 
Published: February 2025

Malawi faces severe climate change impacts, with 30 climate-related disasters recorded in 20 years, causing over 4000 deaths, affecting 2.6 million people and resulting in economic losses of over $1 billion. The southern region, especially Chikwawa District, is hit the hardest, experiencing 40% of these disasters. In light of this, the study aimed to assess organisations’ capacity and obstacles to collaborative approaches for adapting and building resilience to climate change-induced extreme weather events. Primary data were collected through a questionnaire distributed among 25 organisations, involving 325 participants. Thematic analysis was employed for qualitative data analysis, and the analytical hierarchy processing (AHP) method was applied to analyse intra-organisational challenges or obstacles to adopting climate resilience strategies. Alarmingly, 90% of organisations suspended operations because of climate-related disasters, with only 5% engaged in flood mitigation approaches. About 67% lacked flood abatement measures, and only 4% had conducted risk assessments. Most enterprises relied on government (80%) and Non-governmental organisations (NGOs) (70%) for resilience. Additionally, 85% of the organisations did not act collectively during extreme weather events, facing challenges such as lack of planning, adaptive capacity, leadership and funding. The results of this research offer a baseline for the organisations within the study area to map the way forward in making sure that the relentless impact of climate change-induced hazards should not always turn into disasters for their livelihoods and also the community at large.Contribution: This study provides a methodology for the identification of barriers to fostering a culture of proactive organisational adaptation to the escalating impacts of climate change for safeguarding lives and livelihood within a neighbourhood.
Cross-sectional study of thyroid associated orbitopathy in a South African thyroid clinic
Authors: De Vasconcelos Sandra , Mustak Hamzah , Mabogo Maanda , Dave Joel 
Published: February 2025

Background: Thyroid-associated ophthalmopathy (TAO) is a common and debilitating manifestation of Graves’ disease (GD) associated with poor clinical outcomes including impaired quality-of-life (QoL) and socio-economic status. Data on TAO in Africa is scarce and unavailable in the South African population.Methods: This descriptive cross-sectional study focussed on GD patients attending the thyroid clinic at Groote Schuur Hospital, in Cape Town, South Africa. Participants were evaluated for TAO activity and severity according to the European Group on Graves’ Orbitopathy (EUGOGO) criteria. Quality-of-life was assessed using the TED-QoL questionnaire.Results: Thyroid-associated ophthalmopathy prevalence was 59.8%. The majority of TAO patients had mild disease (n = 73; 59.8%). Based on the severity score alone, moderate to severe disease (n = 41; 33.6%) and sight-threatening disease (n = 8; 6.6%) were identified and referred for further ophthalmological intervention. There was a statistically significant increase in the QoL score with an increase in the severity score (p 0.05).Conclusion: The prevalence of orbitopathy was found to be higher than that reported from other continents, but our severity distribution was similar. This study emphasised the importance of evaluating severity as well as the psychosocial aspect of TAO to allow for the identification of and interdisciplinary management of patients to improve patient outcomes.Contribution: This study was the first to attempt to determine the prevalence and severity of TAO in South Africa. The importance of early TAO detection using both, a clinical and psychosocial tool, is highlighted in this study to reduce the complications associated with TAO.
Healthcare professionals’ knowledge and attitudes on termination of pregnancy in eThekwini
Authors: Singh Tashnee , Naidoo Kantharuben 
Published: February 2025

Background: While the Choice on Termination of Pregnancy (CTOP) Act No. 92 was legalised in 1996 permitting termination of pregnancy (TOP) to be accessed at various public health facilities in South Africa, unsafe abortions continue to take place outside of legally designated facilities. The aim of this study was to explore the knowledge, attitudes and practices of healthcare professionals regarding TOP services at public primary healthcare (PHC) centres in the central business district (CBD) of the eThekwini Municipality in KwaZulu-Natal Province, South Africa.Methods: This quantitative, descriptive analysis used a questionnaire to obtain data from the healthcare professionals on four areas: demographic details, knowledge of (8 questions), attitudes to (10 questions) and practices (10 questions) regarding TOP services.Results: Among the 91 participants (whose ages ranged from 32 to 48 years), 91.2% were female, 93.4% belonged to the Christian faith, 42.9% were professional nurses and 74.8% had more than 5 years’ work experience. The mean of the overall knowledge, attitude and practice score was 51.7%, 67.4% and 62.8%, respectively, which indicated poor knowledge, moderate attitude and unacceptable practice.Conclusion: While some healthcare professionals’ knowledge regarding TOP services was poor, their personal beliefs may have contributed to their attitudes and practices regarding whether to assist their patients to access such services, despite it being legal.Contribution: This study provides insight into the health worker barriers that impede TOP service provision and access in the CBD of eThekwini.
Type and antibiotic susceptibility of bacteria cultured in paediatric acute appendicitis
Authors: Brits Elizabeth , Kruger Estie , Fivaz Karlize , Oosthuizen Koot , Joubert Mariska , Van Pletzen Petro-Mari , Roux Ronelle , Fourie Tahlita , Van Aswegen Trewhella , Sempa Joseph B. , Le Grange Susanna 
Published: February 2025

Background: Studying the microbial profile and their antibiotic resistance in paediatric appendicitis is essential for tracking susceptibility, guiding treatment choices and ensuring effectiveness. Understanding variations in therapies can improve outcomes and reduce complications. Despite its importance, limited research has been conducted in South Africa on microbial profiles and antibiotic resistance in paediatric appendicitis.Objectives: To identify bacteria cultured from pus specimens obtained from paediatric patients with acute appendicitis and determine their antibiotic susceptibility.Method: This was a prospective case series of children aged 13 years and younger, who had appendectomies for acute appendicitis. Data were collected via REDCap and analysed using R software. Pus swabs were obtained for microscopy, culture and sensitivity of organisms isolated.Results: The study comprised 20 patients, of whom 12 (60%) were male. Most cases (n = 17; 85%) were complicated appendicitis. Escherichia coli was the most prevalent bacterial species isolated, accounting for 60% of cases, while no bacterial growth was observed in 30% of cases. All the isolates (100%) were susceptible to cefepime, gentamicin, amikacin, ertapenem, imipenem and meropenem, while high sensitivity rates of 92.9% were found for ciprofloxacin, ceftazidime and piperacillin-tazobactam. Short-term complications (predominantly surgical site infections) were present in 6 patients (30%).Conclusion: Escherichia coli was the most common bacterium in paediatric acute appendicitis, with all isolates sensitive to ciprofloxacin.Contribution: Regional monitoring and research are useful to adapt protocols and combat increasing antibiotic resistance.
Serum Soluble Endocan Might Be a Predictor of Preterm Labor
Authors: Sachan Rekha , Shahi Anamika , Sachan Pushplata , Shyam Radhey , Patel Munna Lal , Ali Wahid 
Published: February 2025

Abstract

Background:
Preterm birth is defined as birth before 37 weeks of gestation. It occurs in 10% of all deliveries worldwide and is a major contributor to perinatal mortality and morbidity. The study aimed to evaluate the role of serum-soluble Endocan levels in the prediction and prognostication of preterm labor.

Materials and Methods:
This was a prospective observational study carried out for 1 year in the Department of Obstetrics and Gynaecology, in collaboration with Pathology. Preterm labor was defined as per ACOG guidelines. After informed consent and ethical clearance from the institutional ethics committee, a total of 130 pregnant women with established preterm labor were recruited, and finally, 124 women were enrolled and further divided according to their gestation age, extreme preterm (n = 1), very preterm (n = 22), moderately preterm (n = 32), late preterm (n = 39), and term (n = 30) pregnancy. Serum endocan level was measured using the ELISA technique using a human ESM1 ELISA kit as per manufacturer protocol.

Results:
94.4% of women were not registered while 52.4% were urban and 41.9% were primigravida, 88.7% had body mass index (BMI) in the normal range. The mean serum endocan level was maximum in women who delivered moderate preterm babies (866.64 ± 43.42 pg/ml). followed by (730.68 ± 107.05 pg/ml) who delivered very preterm and almost equal to late preterm (659.21 ± 68.17 pg/ml) and term delivery (662.50 ± 38.30 pg/ml). The mean serum endocan level was higher (839.52 ± 81.16 pg/ml) in women who delivered within 24 h.

Conclusion:
Serum endocan might be a good prognostic marker in preterm labor; adequate antenatal care is required to prevent preterm labor.
Association between improved erectile function and dietary patterns: a systematic review and meta-analysis
Authors: Yang Bin , Wei Chao , Zhang Yu-Cong , Ma De-Lin , Bai Jian , Liu Zhuo , Liu Xia-Ming , Liu Ji-Hong , Yuan Xiao-Yi , Yao Wei-Min 
Published: February 2025

Abstract
Erectile dysfunction (ED) is prevalent among men, but its relationship with dietary habits is uncertain. The aim of our study was to assess whether dietary patterns enhance erectile function by reviewing the literature published before August 1, 2022, via PubMed, Web of Science, and EMBASE databases. The data compiled included author details; publication dates, countries, treatments, patient numbers, ages, follow-ups, and clinical trial outcomes, such as ED cases, odds ratios (ORs), confidence intervals (CIs), and International Index of Erectile Function-5 (IIEF-5) scores with means and standard deviations. An analysis of 14 studies with 27 389 participants revealed that plant-based diets (OR = 0.71, 95% CI: 0.66–0.75; P < 0.00001), low-fat diets (OR = 0.27, 95% CI: 0.13–0.53; P = 0.0002), and alternative diets such as intermittent fasting and organic diets (OR = 0.54, 95% CI: 0.36–0.80; P = 0.002) significantly reduced ED risk. High-protein low-fat diets (hazard ratio [HR] = 1.38, 95% CI: 1.12–1.64; P < 0.00001) and high-carb low-fat diets (HR = 0.79, 95% CI: 0.55–1.04; P < 0.00001) improved IIEF-5 scores. Combined diet and exercise interventions decreased the likelihood of ED (OR = 0.49, 95% CI: 0.28–0.85; P = 0.01) and increased the IIEF-5 score (OR = 3.40, 95% CI: 1.69–5.11; P < 0.0001). Diets abundant in fruits and vegetables (OR = 0.97, 95% CI: 0.96–0.98; P < 0.00001) and nuts (OR = 0.54, 95% CI: 0.37–0.80; P = 0.002) were also correlated with lower ED risk. Our meta-analysis underscores a strong dietary-ED association, suggesting that low-fat/Mediterranean diets rich in produce and nuts could benefit ED management.
Risk factors of scrub typhus infection in children and adults in Kerala, south India
Authors: Renu Govindarajan , Jaganathasamy Nagaraj , Ranganathan Krishnamoorthi , Kumari Krishna , Kumar Ashwani , Paulraj Philip Samuel 
Published: February 2025

Objective:
To identify the risk factors for acquiring scrub typhus infection among all age group.

Methods:
A case-control study was carried out from June to December 2019 in collaboration with the Department of Health Services, Kerala. 136 Of serologically confirmed scrub typhus reported during 2018 were included and 270 age and sex-matched healthy controls were selected randomly from different locations in the same area where the cases were reported. The risk factors identified were compared between cases and controls, using univariate and multivariable logistic regression analysis to identify the risk factors for scrub typhus infection.

Results:
Some key factors like house type with individuals residing in houses with concrete roofs are associated with a higher risk of scrub typhus infection compared to tiled roofs (aOR 0.14, 95% CI 0.36-0.56, P=0.005). Housewives exhibit a significantly higher risk (aOR 3.97, 95% CI 2.15-8.94, P=0.038) of scrub typhus infection. Environmental factors, including the presence of rats (aOR 3.48, 95% CI 1.19-6.53, P=0.023), the presence of domestic animals (aOR 2.98, 95% CI 1.67-5.19, P<0.001), wet agricultural fields around the house (aOR 3.64, 95% CI 1.50-6.54, P<0.001), and hygiene practices like not changing clothes after work (aOR 2.64, 95% CI 1.37-4.68, P=0.024), and disposing of the wastes in their own yard (aOR 4.79, 95% CI 3.78-9.55, P=0.043) are identified as significant high-risk factors for scrub typhus infection.

Conclusions:
These findings will be very useful to create awareness among the public and to undertake a detailed control strategy for scrub typhus.