bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Rate of Missed Lateral Meniscus Posterior Root Tears on Preoperative Magnetic Resonance Imaging
Authors: Krych Aaron J. , Wu Isabella T. , Desai Vishal S. , Murthy Naveen S. , Collins Mark S. , Saris Daniel B.F. , Levy Bruce A. , Stuart Michael J. 
Published: April 2018

Background: Lateral meniscus posterior root tears (LMPRTs), if left untreated, can cause devastating effects to the knee, with rapid articular cartilage degeneration and loss of the meniscus as a secondary stabilizer. Detection and surgical repair of these defects have been linked to favorable outcomes, but preoperative identification of LMPRTs continues to be challenging. Purpose: To determine the rate of LMPRTs diagnosed preoperatively on magnetic resonance imaging (MRI) in a consecutive series of arthroscopically confirmed LMPRTs. Study Design: Case series; Level of evidence, 4. Methods: A retrospective cohort of 45 consecutive patients with arthroscopically confirmed LMPRTs between 2010 and 2017 were included in this study. The preoperative MRI report for each patient was evaluated and compared with intraoperative findings. Each preoperative MRI study was then reviewed by 2 fellowship-trained musculoskeletal radiologists who worked in consensus. Results: A total of 45 patients (32 males, 13 females) with arthroscopically confirmed LMPRTs and a mean age of 27 years (range, 14-54 years) were included in the study. Only 15 of 45 LMPRTs (33%) were initially diagnosed on preoperative MRI. Past or concurrent anterior cruciate ligament (ACL) reconstruction was present in 37 of 45 cases (82%). Upon retrospective review, 15 of the 30 missed LMPRTs were “clearly evident,” 12 “subtly evident,” and 3 “occult” (unavoidably missed). There were no significant differences in the rate of LMPRT diagnosis based on history of prior knee surgery, meniscus extrusion, or tearing of the meniscofemoral ligament. Conclusion: Despite improved identification of other meniscus tear patterns on MRI, a high percentage of LMPRTs were still missed. In the setting of previous ACL reconstruction, if the root cannot be confidently identified, the MRI interpretation should indicate that “the root is poorly visualized” to alert the surgeon to thoroughly evaluate this structure. The surgeon should maintain a high index of suspicion and carefully probe the posterior root of the lateral meniscus at the time of arthroscopy, especially in cases of ACL injury.
Linking Inuit Knowledge and Public Health for Improved Child and Youth Oral Health in NunatuKavut
Authors: Martin D. , McNally M. , Castleden H. , Worden-Driscoll I. , Clarke M. , Wall D. , Ley M. 
Published: April 2018

The oral health of Inuit children in Canada has been identified as a public health crisis. Although efforts are being made to identify and address ways to deal with this crisis, current policy and program approaches are largely entrenched within the prevailing paradigm of dental science to the exclusion of Indigenous people’s understandings of health. This article reports qualitative findings of a larger study aimed at identifying, understanding, and addressing rates of oral disease among children living in NunatuKavut, a cluster of small, coastal Inuit communities located in southern Labrador, Canada. Through 18 focus groups with youth (n = 86), caregivers (n = 22), and interviews with key informant (n = 13), this study begins to elucidate southern Inuit understandings of oral health. Theorized using Two-Eyed Seeing, an Indigenous approach to balancing both Indigenous and non-Indigenous understandings of the world, the findings reported here reveal 3 themes, each of which is crosscut by historical and contemporary dimensions: 1) (w)holistic conceptualizations of health are essential to good oral health, 2) achieving optimal oral health is prohibitive for Inuit communities, and 3) community-engaged oral health service delivery is needed. Our recommendations have implications for improved oral public health service delivery for Inuit communities, in that the inclusion of Inuit perspectives on oral health should form an instrumental element of oral public health service delivery. Knowledge Transfer Statement: The results of this study may be used by clinicians and oral health educators to inform approaches to oral health service delivery within the context of Indigenous communities. It may also be used by policymakers to recognize how historical and contemporary issues of colonization relate to the formation of oral health–related policies.
Defective RAB1B-related megakaryocytic ER-to-Golgi transport in RUNX1 haplodeficiency: impact on von Willebrand factor
Authors: Jalagadugula Gauthami , Goldfinger Lawrence E. , Mao Guangfen , Lambert Michele P. , Rao A. Koneti 
Published: April 2018

Key Points
GTPase RAB1B is a direct transcriptional target of RUNX1 in MK/platelets and is downregulated in RUNX1 haplodeficiency. RUNX1 downregulation is associated with defective RAB1B-related ER-to-Golgi transport and alterations in α-granule vWF.
Risk of recurrent venous thromboembolism according to baseline risk factor profiles
Authors: Prins Martin H. , Lensing Anthonie W. A. , Prandoni Paolo , Wells Philip S. , Verhamme Peter , Beyer-Westendorf Jan , Bauersachs Rupert , Bounameaux Henri , Brighton Timothy A. , Cohen Alexander T. , Davidson Bruce L. , Decousus Hervé , Kakkar Ajay K. , van Bellen Bonno , Pap Akos F. , Homering Martin , Tamm Miriam , Weitz Jeffrey I. 
Published: April 2018

Key Points
The risk of recurrence in patients with VTE provoked by minor transient or persistent risk factors is uncertain. The risk of recurrence with VTE provoked by minor transient or persistent risk factors is similar to that with unprovoked VTE.
Outdoor air pollution, exhaled 8-isoprostane and current asthma in adults: the EGEA study
Authors: Havet Anaïs , Zerimech Farid , Sanchez Margaux , Siroux Valérie , Le Moual Nicole , Brunekreef Bert , Stempfelet Morgane , Künzli Nino , Jacquemin Bénédicte , Matran Régis , Nadif Rachel 
Published: April 2018

Associations between outdoor air pollution and asthma in adults are still scarce, and the underlying biological mechanisms are poorly understood. Our aim was to study the associations between 1) long-term exposure to outdoor air pollution and current asthma, 2) exhaled 8-isoprostane (8-iso; a biomarker related to oxidative stress) and current asthma, and 3) outdoor air pollution and exhaled 8-iso.Cross-sectional analyses were conducted in 608 adults (39% with current asthma) from the first follow-up of the French case–control and family study on asthma (EGEA; the Epidemiological study of the Genetic and Environmental factors of Asthma). Data on nitrogen dioxide, nitrogen oxides, particulate matter with a diameter ≤10 and ≤2.5 µm (PM10and PM2.5), road traffic, and ozone (O3) were from ESCAPE (European Study of Cohorts for Air Pollution Effects) and IFEN (French Institute for the Environment) assessments. Models took account of city and familial dependence.The risk of current asthma increased with traffic intensity (adjusted (a)OR 1.09 (95% CI 1.00–1.18) per 5000 vehicles per day), with O3exposure (aOR 2.04 (95% CI 1.27–3.29) per 10 µg·m−3) and with exhaled 8-iso concentration (aOR 1.50 (95% CI 1.06–2.12) per 1 pg·mL−1). Among participants without asthma, exhaled 8-iso concentration increased with PM2.5exposure (adjusted (a)β 0.23 (95% CI 0.005–0.46) per 5 µg·m−3), and decreased with O3and O3-summerexposures (aβ −0.20 (95% CI −0.39– −0.01) and aβ −0.52 (95% CI −0.77– −0.26) per 10 µg·m−3, respectively).Our results add new insights into a potential role of oxidative stress in the associations between outdoor air pollution and asthma in adults.
Risk of tuberculosis transmission among healthcare workers
Authors: Diel Roland , Niemann Stefan , Nienhaus Albert 
Published: April 2018

Data from a prospective molecular-epidemiological study (1997–2015) of patients with culture-confirmed tuberculosis in Hamburg, Germany, were evaluated to assess the occupational risk ofMycobacterium tuberculosiscomplex transmission in a low-incidence setting.Isolates ofM. tuberculosiscomplex were genotyped using IS6110 restriction fragment length polymorphism analysis. Results of structured questionnaires, geographical mapping and additional patient interviews were used for confirming epidemiological links.Out of the 2393 cases, 918 (38.4%) were classified into 224 clusters comprising 2–70 patients per cluster. Among the 918 cluster members, epidemiological links could be confirmed in 340 (37.0%) patients. In total, 55 (2.3%) patients were healthcare workers; 26 healthcare workers remained unclustered, but 29 healthcare workers belonged to cluster groups. Conventional contact tracing performed before genotyping to identify sources of the reported index cases detected only 73 (3.1%) patients.Logistic regression analysis confirmed work in the healthcare sector as strongest predictor for clustering of patients with verified epidemiological links (odds ratio (OR) 3.1, 95% CI 1.6–5.9), followed by alcoholism (OR 2.3, 95% CI 1.7–3.2) and sputum smear positivity (OR 1.8, 95% CI 1.4–2.3). Immigrants were more likely to be cluster nonmembers (OR 0.3, 95% CI 0.3–0.5). Recent transmission in Hamburg within the 19-year study period was found to be strongly associated with working in a healthcare facility. Although clusters also include many “imported” strains from abroad or regional highly prevalentM. tuberculosisstrains with no evident epidemiological connection, routine molecular-epidemiological survey is indispensable to optimising and controlling the effectiveness of TB control strategies in German healthcare settings.
Case Report: An incidental finding of an metastases noted in a “cancer to cancer adrenal tumor ” from a large malignant nerve sheath tumor of the thigh
Authors: Shaines Matthew D. , Arora Shitij 
Published: April 2018

Current guidelines are vague for the management of soft tissue sarcomas, specifically malignant peripheral nerve sheath tumors (MPNST), regarding staging the disease with the use of routine abdominal imaging. The most recent guidelines from the National Comprehensive Cancer Network (NCCN) recommends to “consider” abdominal/pelvic CT imaging for certain sub groups of sarcomas (e.g., myxoid/round cell liposarcoma, epithelial sarcoma, angiosarcoma, leiomyosarcoma), but provide no guidance on other sarcoma subtypes regardless of tumor size. We report a case of a very large large MPNST in a 40 year-old-female with neurofibromatosis type 1 who was incidentally found to have adrenal metastasis.
Usage of unicompartmental knee arthroplasty
Authors: Murray D. W. , Parkinson R. W. 
Published: April 2018

Unicompartmental knee arthroplasty (UKA) has numerous advantages over total knee arthroplasty (TKA) and one disadvantage, the higher revision rate. The best way to minimize the revision rate is for surgeons to use UKA for at least 20% of their knee arthroplasties. To achieve this, they need to learn and apply the appropriate indications and techniques. This would decrease the revision rate and increase the number of UKAs which were implanted, which would save money and patients would benefit from improved outcomes over their lifetime. Cite this article: Bone Joint J 2018;100-B:432–5.
Arthroscopically assisted fixation of Hawkins type II talar neck fractures
Authors: Wagener J. , Schweizer C. , Zwicky L. , Horn Lang T. , Hintermann B. 
Published: April 2018

Aims Arthroscopically controlled fracture reduction in combination with percutaneous screw fixation may be an alternative approach to open surgery to treat talar neck fractures. The purpose of this study was thus to present preliminary results on arthroscopically reduced talar neck fractures. Patients and Methods A total of seven consecutive patients (four women and three men, mean age 39 years (19 to 61)) underwent attempted surgical treatment of a closed Hawkins type II talar neck fracture using arthroscopically assisted reduction and percutaneous screw fixation. Functional and radiological outcome were assessed using plain radiographs, as well as weight-bearing and non-weight-bearing CT scans as tolerated. Patient satisfaction and pain sensation were also recorded. Results Primary reduction was obtained arthroscopically in all but one patient, for whom an interposed fracture fragment had to be removed through a small arthrotomy to permit anatomical reduction. The quality of arthroscopic reduction and restoration of the talar geometry was excellent in the remaining six patients. There were no signs of talar avascular necrosis or subtalar degeneration in any of the patients. In the whole series, the functional outcome was excellent in five patients but restricted ankle movement was observed in two patients. All patients had a reduction in subtalar movement. At final follow-up, all patients were satisfied and all but one patient were pain free. Conclusion Arthroscopically assisted reduction and fixation of talar neck fractures was found to be a feasible treatment option and allowed early functional rehabilitation. Cite this article: Bone Joint J 2018;100-B:461–7.
Current concepts in the surgical management of adolescent idiopathic scoliosis
Authors: Tambe A. D. , Panikkar S. J. , Millner P. A. , Tsirikos A. I. 
Published: April 2018

Adolescent idiopathic scoliosis (AIS) is a complex 3D deformity of the spine. Its prevalence is between 2% and 3% in the general population, with almost 10% of patients requiring some form of treatment and up to 0.1% undergoing surgery. The cosmetic aspect of the deformity is the biggest concern to the patient and is often accompanied by psychosocial distress. In addition, severe curves can cause cardiopulmonary distress. With proven benefits from surgery, the aims of treatment are to improve the cosmetic and functional outcomes. Obtaining correction in the coronal plane is not the only important endpoint anymore. With better understanding of spinal biomechanics and the long-term effects of multiplanar imbalance, we now know that sagittal balance is equally, if not more, important. Better correction of deformities has also been facilitated by an improvement in the design of implants and a better understanding of metallurgy. Understanding the unique character of each deformity is important. In addition, using the most appropriate implant and applying all the principles of correction in a bespoke manner is important to achieve optimum correction.In this article, we review the current concepts in AIS surgery.Cite this article: Bone Joint J 2018;100-B:415–24.
Improving quality and safety in paediatric spinal surgery
Authors: Miyanji F. , Greer B. , Desai S. , Choi J. , Mok J. , Nitikman M. , Morrison A. 
Published: April 2018

Aims The aim of this study was to evaluate improvements in the quality and safety of paediatric spinal surgery following the implementation of a specialist Paediatric Spinal Surgical Team (PSST) in the operating theatre. Patients and Methods A retrospective consecutive case study of paediatric spinal operations before (between January 2008 and December 2009), and after (between January 2012 and December 2013) the implementation of PSST, was performed. A comparative analysis of outcome variables including surgical site infection (SSI), operating time (ORT), blood loss (BL), length of stay (LOS), unplanned staged procedures (USP) and transfusion rates (allogenic and cell-saver) was performed between the two groups. The rate of complications during the first two postoperative years was also compared between the groups. Results There were 130 patients in the pre-PSST group and 277 in the post-PSST group. The age, gender, body mass index (BMI), preoperative Cobb angle of the major curve and the number of levels involved were similar between the groups. There were statistically significant differences in SSI, ORT, LOS, allogenic blood transfusion volume (ABTV), and USPs between the groups. There was a 94% decrease in the rate of SSI's in the post-PSST group. Patients in the post-PSST group had a mean reduction in ORT of 53 minutes (sd 7.7) (p = 0.013), LOS by 5.4 days (sd 1.8) (p = 0.019), and ABTV by 226.3 ml (sd 28.4) (p < 0.001). There were significantly more USPs in the pre-PSST group (6.2%) compared with the post-PSST group (2.9%) (p = 0.001). Multivariate regression showed that the effect of PSST remained significant for ORT, LOS, BL, ABVT and cell-saver amount transfused (p = 0.0001). The odds of having a SSI were tenfold higher and the odds of receiving a blood transfusion were 2.4 times higher, respectively, in the pre-PSST group (p = 0.004 and p = 0.011). The rate of complications within the first two postoperative years was significantly higher in the pre-PSST group (13.1%) compared with the post-PSST group (4.3%) (p < 0.001). Conclusion The implementation of a PSST in the operating theatre significantly improves the outcomes in paediatric spinal surgery. Cite this article: Bone Joint J 2018;100-B:493–8.
Examining the Relationship between Regulatory Quality and Forest Product Exports to India: A Gravity Model Approach
Authors: Das Joy , Tanger Shaun M. , Kennedy P. Lynn , Vlosky Richard P. 
Published: April 2018

Abstract
The value of aggregate forest product exports to India has increased from about $1.5 billion in 2003 to about $5.4 billion in 2013. Although many of the forest product resources can be sourced from within India, the subcontinent must also source forest products from trading partners, in the form of wood product exports. This presents many economic challenges and opportunities for wood product markets and trade, as India is the second-largest importer of wood products in the world. In this study, we focus on the effect of regulatory quality on forest products exports by partner countries to India. Using a panel of trade flows during 2009 through 2013 of 143 partner countries exporting forest products to India, we estimate an augmented gravity trade model to capture the effect of relevant variables on the outflow of aggregate forest products and disaggregate paper and paperboard, wood pulp, fiberboard, veneers, sawn wood, industrial roundwood, and plywood products from partner countries to India. Results from the analysis are mixed; regulatory quality is found to have positive correlation with exports to India in some cases (paper and paperboard products and wood pulps) and no correlation in a few instances (fiberboard, veneer sheets, sawn wood, industrial roundwood, and plywood). Other explanatory variables such as the distance between the partner country and India, forest area of partner country relative to forest area of India, gross domestic product, population, and trade agreements are mostly found to have positive or negative significant effects on trade, varying across different sectors.
ANAK MENDAMBAKAN ORANG TUA YANG UTUH
Authors: Lila Napsiah Satra 
Published: April 2018

Judul Asli : Memutus Rantai Ketidakadilan GLobal Care dalam Pengasuhan Anak Tenaga Kerja Indonesia Perempuan (TKIP)Pengarang : Maria Ulfah AnsorPenerbit : Yayasan Obor, 2017Tebal buku : 289 Halaman.
IMPLICATION OF CONFLICT OF OWNERSHIP REGIONAL ASSETS IN THE EXPANSION OF BAU-BAU CITY IN THE TERRITORY OF EX BUTON SULTANATE
Authors: Tuwu Darmin 
Published: April 2018

The article entitled "The Conflict of Ownership Regional Asset Between Government of Buton Regency and Government of Bau-Bau Municipal " is part of my thesis in the Department of Sociology Faculty of Political and Social Sciences Gadjah Mada University. The conflict of two regional governments began when Kotif Bau-Bau was upgraded to Bau Bau City, where almost all of district's assets Buton regency's (premier) are within in the Bau-Bau City as the New Autonomous Region. This research apply qualitative approach using case study aiming to elaborate the context of the conflicts regional asset and their implications on both local governments, Buton Regency and Bau-Bau City. The results showed that the context of the conflict of ownership of regional assets was triggered by the difference of opinion on the contents of Law Number 13 Year 2001 related to the control of regional asset that is in the area of Bau-Bau City as the New Autonomous Region. The is no conclusive solution to the conflict that began in 2001, The effects of such conflicts are apparent in public services, Local Original Income, and social segregation.Konflik antara dua pemerintahan daerah ini, berawal ketika Kotif Bau-Bau ditingkatkan statusnya menjadi Kota Bau Bau, di mana hampir seluruh aset daerah kabupaten Buton (kabupaten induk) berada dalam wilayah Kota Bau-Bau selaku Daerah Otonomi Baru. Penelitian ini menggunakan pendekatan kualitatif dengan menggunakan studi kasus yang bertujuan untuk menguraikankonteks konflik aset daerah dan implikasinya terhadap kedua pemerintah daerah, Kabupaten Buton dan Kota Bau-Bau. Hasil penelitian menunjukkan bahwa konteks konflik kepemilikan aset daerah dipicu oleh perbedaan pendapat atas isi Undang-Undang Nomor 13 Tahun 2001 terkait penguasaan aset daerah yang berada di wilayah Kota Bau-Bau sebagai Kota Baru, Daerah Otonom Baru. Tidak ada solusi konklusif untuk konflik yang dimulai pada tahun 2001, Dampak dari konflik tersebut terlihat pada layanan publik, Pendapatan Asli Daerah, dan pemisahan sosial.Keywords: Conflict, Asset, Autonomy and Bau-Bau City
POSSÍVEIS INTERAÇÕES MEDICAMENTOSAS EM PACIENTES POLIMEDICADOS DE NOVO HAMBURGO, RS, BRASIL
Authors: Da Silva Denis Tasso , Miorelli Campos César Augusto , Vargas Tainara Gomes , Ziulkoski Ana Luiza , Andrighetti Letícia Hoerbe , Perassolo Magda Susana 
Published: April 2018

A expectativa de vida da população mundial tem aumentado e consequentemente, tem ocorrido aumento no nível de doenças crônico degenerativas e acréscimo no uso concomitantemente de medicamentos, caracterizando a polifarmácia, o que aumenta o risco de interações medicamentosas (IM). Desta forma, este trabalho teve como objetivo identificar possíveis IM entre os medicamentos utilizados por um grupo de pacientes polimedicados de Novo Hamburgo, RS. Foi realizado um estudo transversal com voluntários de um projeto de pesquisa durante sua entrevista inicial. Foram avaliados dados sócio-demográficos, patologias, medicamentos utilizados e suas IM. As doenças de base foram classificadas de acordo com o código internacional de doenças (CID-10) e os medicamentos utilizados classificados conforme os padrões Anatomical Therapeutic Chemical (ATC). As IM foram identificadas e classificadas conforme literatura e pelo sistema Micromedex®. Participaram do estudo 67 pacientes (62±9 anos, maioria do sexo feminino,74,6%), sendo que 76,1% dos pacientes apresentaram probabilidade de desenvolverem algum tipo de IM. Ao todo foram identificadas 157 possíveis IM, sendo 3,0±2,2 interações por paciente. Destas, 69,4% foram consideradas moderadas, 19,8% graves e 10,8% leves. 51,6% das interações ocorrem por mecanismo farmacodinâmico, 31,9% farmacocinético e 16,5% apresentam ambos mecanismos. A IM mais prevalente foi entre ácido acetilsalicílico e hidroclorotiazida. A maioria das IM identificadas foi do tipo grave ou moderada, com riscos consideráveis à saúde do paciente. Assim, as IM identificadas podem comprometer a segurança do paciente, evidenciando a relevância deste tema e a necessidade de avaliar e monitorar a terapêutica medicamentosa.
A CRIAÇÃO DO CONHECIMENTO CIENTÍFICO E O PAPEL DOS PERIÓDICOS NA DIFUSÃO DE RESULTADOS
Authors: Oliveira Anselmo Gomes de , Silveira Damaris 
Published: April 2018

O conhecimento científico surgiu da necessidade do ser humano se relacionar mais intimamente com o meio onde vive e a querer conhecer melhor o funcionamento das coisas em seu redor. Esse interesse fez com que o homem pudesse entender os fenômenos naturais, a constituição e o funcionamento dos organismos vivos, a arquitetura dos materiais inertes, os fenômenos físicos e químicos do meio ambiente, entre outros, e começasse a interferir na maioria dos processos que o rodeavam.