bluuebunny/crossref_metadata_2025_split huggingface dataset:
Broad-band spectral study of X-ray transient MAXI J1820+070 using Swift/XRT and NuSTAR
Authors: Bharali Priya , Chauhan Jaiverdhan , Boruah Kalyanee 
Published: June 2019

ABSTRACT
We report on a NuSTAR and Swift/XRT observation of the newly discovered X-ray transient MAXI J1820+070. Swift/XRT and NuSTAR have concurrently observed the newly detected source on 2018 March 14. We have simultaneously fitted the broad-band spectra obtained from Swift/XRT and NuSTAR. The observed joint spectra in the energy range 0.6–78.0 keV are well modeled with a weak disc black-body emission, dominant thermal Comptonization, and relativistic reflection fraction. We have detected a fluorescent Iron-Kα line relativistically broadened and a Compton hump at ∼30 keV. We constrain the inner disc radius as well as the disc inclination angle, and their values are found to be 4.1$^{+0.8}_{-0.6}$RISCO (where RISCO ≡ radius of the innermost stable circular orbit) or 5.1$^{+1.0}_{-0.7}$ rg (where rg ≡ gravitational radius) and 29.8$^{+3.0}_{-2.7}$°, respectively. The best-fitting broad-band spectra suggest that the source was in the hard state and evolving. The source emission is best described by weak thermal emission along with strong thermal Comptonization from a relatively cold, optically thick, geometrically thin and ionized accretion disc. X-ray spectral modeling helps us to understand the accretion and ejection properties in the vicinity of the compact object.
Dispersion of sausage waves in coronal waveguides with transverse density structuring
Authors: Lopin I , Nagorny I 
Published: June 2019

ABSTRACT
We study dispersion properties of fast-sausage waves in a radially structured coronal magnetic tube with continuous radial density distribution. The models, containing either a non-uniform core or inhomogeneous external medium are considered. The dispersion relations are obtained for a power law density distribution in the corresponding non-uniform region, where the power-law index controls the steepness of the tube boundary. The governing wave equations with varying coefficients were solved with the Wentzel–Kramers–Brillouin (WKB) approximation. The model with the non-uniform core supports the existence of trapped and leaky sausage modes. The density non-uniformity in the core modifies the values of cut-off wave numbers kc. The smaller values of cut-offs, normalized to the effective tube radius r0, correspond to the smaller power index p. The wave dispersion (i.e. dVph/dk) decreases for smaller p. This occurs in the range of not too small longitudinal wave numbers k > kc. For the model, containing inhomogeneous environment the basic dispersion properties are generally identical to that for the monolithic tube model, studied in Lopin & Nagorny (2015b). The waves are trapped for all wave numbers, if the power-law index 0 < n < 2. There are both trapped and leaky regimes for n ≥ 2. The wave dispersion decreases for smaller n, in the range of the intermediate values of the longitudinal wave numbers k > kc. The seismological application of the obtained results is discussed.
The Milky Way Project second data release: bubbles and bow shocks
Authors: Jayasinghe Tharindu , Dixon Don , Povich Matthew S , Binder Breanna , Velasco Jose , Lepore Denise M , Xu Duo , Offner Stella , Kobulnicky Henry A , Anderson Loren D , Kendrew Sarah , Simpson Robert J 
Published: June 2019

ABSTRACT
Citizen science has helped astronomers comb through large data sets to identify patterns and objects that are not easily found through automated processes. The Milky Way Project (MWP), a citizen science initiative on the Zooniverse platform, presents internet users with infrared (IR) images from Spitzer Space Telescope Galactic plane surveys. MWP volunteers make classification drawings on the images to identify targeted classes of astronomical objects. We present the MWP second data release (DR2) and an updated data reduction pipeline written in python. We aggregate ∼3 million classifications made by MWP volunteers during the years 2012–2017 to produce the DR2 catalogue, which contains 2600 IR bubbles and 599 candidate bow shock driving stars. The reliability of bubble identifications, as assessed by comparison to visual identifications by trained experts and scoring by a machine-learning algorithm, is found to be a significant improvement over DR1. We assess the reliability of IR bow shocks via comparison to expert identifications and the colours of candidate bow shock driving stars in the 2MASS point-source catalogue. We hence identify highly reliable subsets of 1394 DR2 bubbles and 453 bow shock driving stars. Uncertainties on object coordinates and bubble size/shape parameters are included in the DR2 catalogue. Compared with DR1, the DR2 bubbles catalogue provides more accurate shapes and sizes. The DR2 catalogue identifies 311 new bow shock driving star candidates, including three associated with the giant H ii regions NGC 3603 and RCW 49.
Evolution of galactic planes of satellites in the eagle simulation
Authors: Shao Shi , Cautun Marius , Frenk Carlos S 
Published: June 2019

ABSTRACT
We study the formation of planes of dwarf galaxies around Milky Way (MW)-mass haloes in the eagle galaxy formation simulation. We focus on satellite systems similar to the one in the MW: spatially thin or with a large fraction of members orbiting in the same plane. To characterize the latter, we introduce a robust method to identify the subsets of satellites that have the most coplanar orbits. Out of the 11 MW classical dwarf satellites, 8 have highly clustered orbital planes whose poles are contained within a 22° opening angle centred around (l, b) = (182°, −2°). This configuration stands out when compared to both isotropic and typical ΛCDM satellite distributions. Purely flattened satellite systems are short-lived chance associations and persist for less than $1\, \rm {Gyr}$. In contrast, satellite subsets that share roughly the same orbital plane are longer lived, with half of the MW-like systems being at least $4\, \rm {Gyr}$ old. On average, satellite systems were flatter in the past, with a minimum in their minor-to-major axes ratio about $9\, \rm {Gyr}$ ago, which is the typical infall time of the classical satellites. MW-like satellite distributions have on average always been flatter than the overall population of satellites in MW-mass haloes and, in particular, they correspond to systems with a high degree of anisotropic accretion of satellites. We also show that torques induced by the aspherical mass distribution of the host halo channel some satellite orbits into the host’s equatorial plane, enhancing the fraction of satellites with coplanar orbits. In fact, the orbital poles of coplanar satellites are tightly aligned with the minor axis of the host halo.
How much does others’ protection matter? Employment protection, future labour market prospects and well-being
Authors: Luecke Christine , Knabe Andreas 
Published: June 2019

Abstract
Employment protection legislation (EPL) is an important determinant of workers’ perceived labour market prospects and also their subjective well-being. Recent studies indicate that it is not only a worker’s own level of protection that matters for individual prospects and well-being, but also that of others. We examine how such cross-effects on well-being are mediated by workers’ perceived risk of job loss and future employability. We apply a structural model to data from the European Quality of Life Survey and the OECD Employment Protection Database. Our results indicate that both permanent and fixed-term workers’ perceived employability is affected by EPL, positively for fixed-term workers and negatively for permanent workers. Stricter protection for permanent workers is positively related to fixed-term workers’ perceived risk of job loss. EPL has significant indirect (cross-)effects on life satisfaction via the mediators. There are no indications for direct, non-mediated effects.
Acute Experimental Pain Responses in Methadone- and Buprenorphine/Naloxone-Maintained Patients Administered Additional Opioid or Gabapentin: A Double-Blind Crossover Pilot Study
Authors: Murnion Bridin Patricia , Rivas Consuelo , Demirkol Apo , Hayes Vicky , Lintzeris Nicholas , Nielsen Suzanne 
Published: June 2019

AbstractObjectiveThe study objective was to identify the analgesic efficacy of three different pharmacological strategies in patients receiving methadone or buprenorphine as opioid agonist treatment (OAT). The three pharmacological approaches, a) increasing maintenance methadone/buprenorphine dose by 30%, b) adding oxycodone, or c) adding a single dose of gabapentin, were compared with a control condition of the participant’s usual OAT dose.DesignA randomized, controlled, double-blinded, double-dummy, within-subject crossover study.SubjectsNine participants on stable doses of methadone and eight participants on stable doses of buprenorphine were recruited.SettingAn outpatient opioid treatment clinic in inner city Sydney, Australia.MethodsThe cold pressor tolerance test was used to examine experimental pain threshold and tolerance. Ratings of subjective drug effects and safety measures (physiological and cognitive) were assessed.ResultsThere was no difference in the primary outcome measures of pain thresholds or tolerance between the conditions examined. Interindividual variability was evident. Differences in some subjective measures were identified, including lower pain recall, lower “bad effects,” and higher global satisfaction in the additional methadone condition. In the buprenorphine arm, increased drug liking and “bad effects” were detected with oxycodone administration, while increased subjective intoxication was identified with gabapentin.ConclusionsThere was no evidence of an objective improvement in analgesia with any condition compared with control. Further research is required to optimize pain management strategies in this population.
Adjuvant treatment for endometrial cancer
Authors: Emons Günter , Vordermark Dirk 
Published: June 2019

Purpose of review
This article reviews and interprets studies on adjuvant treatment of endometrial cancer published during the last 18 months.

Recent findings
For patients with intermediate and high intermediate risk endometrial cancer, vaginal brachytherapy remains the adjuvant therapy of choice. New molecular markers might help to define patients in this group for whom observation only is sufficient and women who might have benefitted from external beam radiotherapy. Preliminary results from large randomized controlled trials have shown that in early stage, high-risk endometrial cancer the addition of chemotherapy to external beam radiotherapy (EBRT) did not improve survival. The combination of vaginal brachytherapy with three courses of chemotherapy resulted in similar progression-free and overall survival (3 years) as EBRT. In stage III high-risk endometrial cancer, the addition of chemotherapy to EBRT improved failure-free survival but not overall survival (immature data). Chemotherapy alone had the same efficacy concerning progression-free and overall survival (immature data).

Summary
Three large randomized clinical trials on the role of adjuvant radio and/or chemotherapy have so far provided only immature results. Discussions about changes of clinical practice should be postponed until mature data from all three trials are available. The impact of new molecular markers for risk stratification will be assessed in ongoing RCTs.
Beam emittance preservation using Gaussian density ramps in a beam-driven plasma wakefield accelerator
Authors: Litos M. D. , Ariniello R. , Doss C. E. , Hunt-Stone K. , Cary J. R. 
Published: June 2019

A current challenge that is facing the plasma wakefield accelerator (PWFA) community is transverse beam emittance preservation. This can be achieved by balancing the natural divergence of the beam against the strong focusing force provided by the PWFA plasma source in a scheme referred to as beam matching. One method to accomplish beam matching is through the gradual focusing of a beam with a plasma density ramp leading into the bulk plasma. Here, the beam dynamics in a Gaussian plasma density ramp are considered, and an empirical formula is identified that gives the ramp length and beam vacuum waist location needed to achieve near-perfect matching. The method uses only the beam vacuum waist beta function as an input. Numerical studies show that the Gaussian ramp focusing formula is robust for beta function demagnification factors spanning more than an order of magnitude with experimentally favourable tolerances for future PWFA research facilities.
This article is part of the Theo Murphy meeting issue ‘Directions in particle beam-driven plasma wakefield acceleration’.
Producing multi-coloured bunches through beam-induced ionization injection in plasma wakefield accelerator
Authors: Vafaei-Najafabadi N. , Amorim L. D. , Adli E. , An W. , Clarke C. I. , Clayton C. E. , Corde S. , Gessner S. , Green S. Z. , Hogan M. J. , Joshi C. , Kononenko O. , Lindstrøm C. A. , Litos M. , Lu W. , Marsh K. A. , Mori W. B. , San Miguel Claveria P. , O'Shea B. , Raj G. , Storey D. , White G. , Xu Xinlu , Yakimenko V. 
Published: June 2019

This paper discusses the properties of electron beams formed in plasma wakefield accelerators through ionization injection. In particular, the potential for generating a beam composed of co-located multi-colour beamlets is demonstrated in the case where the ionization is initiated by the evolving charge field of the drive beam itself. The physics of the processes of ionization and injection are explored through OSIRIS simulations. Experimental evidence showing similar features are presented from the data obtained in the E217 experiment at the FACET facility of the SLAC National Laboratory.
This article is part of the Theo Murphy meeting issue ‘Directions in particle beam-driven plasma wakefield acceleration’.
FLASHForward: plasma wakefield accelerator science for high-average-power applications
Authors: D'Arcy R. , Aschikhin A. , Bohlen S. , Boyle G. , Brümmer T. , Chappell J. , Diederichs S. , Foster B. , Garland M. J. , Goldberg L. , Gonzalez P. , Karstensen S. , Knetsch A. , Kuang P. , Libov V. , Ludwig K. , Martinez de la Ossa A. , Marutzky F. , Meisel M. , Mehrling T. J. , Niknejadi P. , Põder K. , Pourmoussavi P. , Quast M. , Röckemann J. -H. , Schaper L. , Schmidt B. , Schröder S. , Schwinkendorf J. -P. , Sheeran B. , Tauscher G. , Wesch S. , Wing M. , Winkler P. , Zeng M. , Osterhoff J. 
Published: June 2019

The FLASHForward experimental facility is a high-performance test-bed for precision plasma wakefield research, aiming to accelerate high-quality electron beams to GeV-levels in a few centimetres of ionized gas. The plasma is created by ionizing gas in a gas cell either by a high-voltage discharge or a high-intensity laser pulse. The electrons to be accelerated will either be injected internally from the plasma background or externally from the FLASH superconducting RF front end. In both cases, the wakefield will be driven by electron beams provided by the FLASH gun and linac modules operating with a 10 Hz macro-pulse structure, generating 1.25 GeV, 1 nC electron bunches at up to 3 MHz micro-pulse repetition rates. At full capacity, this FLASH bunch-train structure corresponds to 30 kW of average power, orders of magnitude higher than drivers available to other state-of-the-art LWFA and PWFA experiments. This high-power functionality means FLASHForward is the only plasma wakefield facility in the world with the immediate capability to develop, explore and benchmark high-average-power plasma wakefield research essential for next-generation facilities. The operational parameters and technical highlights of the experiment are discussed, as well as the scientific goals and high-average-power outlook.
This article is part of the Theo Murphy meeting issue ‘Directions in particle beam-driven plasma wakefield acceleration’.
Directions in plasma wakefield acceleration
Authors: Hidding B. , Foster B. , Hogan M. J. , Muggli P. , Rosenzweig J. B. 
Published: June 2019

This introductory article is a synopsis of the status and prospects of particle-beam-driven plasma wakefield acceleration (PWFA). Conceptual and experimental breakthroughs obtained over the last years have initiated a rapid growth of the research field, and increased maturity of underlying technology allows an increasing number of research groups to engage in experimental R&D. We briefly describe the fundamental mechanisms of PWFA, from which its chief attractions arise. Most importantly, this is the capability of extremely rapid acceleration of electrons and positrons at gradients many orders of magnitude larger than in conventional accelerators. This allows the size of accelerator units to be shrunk from the kilometre to metre scale, and possibly the quality of accelerated electron beam output to be improved by orders of magnitude. In turn, such compact and high-quality accelerators are potentially transformative for applications across natural, material and life sciences.
This overview provides contextual background for the manuscripts of this issue, resulting from a Theo Murphy meeting held in the summer of 2018.
This article is part of the Theo Murphy meeting issue ‘Directions in particle beam-driven plasma wakefield acceleration’.
Spatiotemporal trends in polychlorinated biphenyl concentrations in seafood based on long-term monitoring and remediation in New Bedford Harbor, Massachusetts
Authors: Crawford Kathryn A. , Schlezinger Jennifer J. , Craffey Paul , Heiger-Bernays Wendy 
Published: June 2019

AbstractElectrical manufacturing near New Bedford Harbor (NBH), MA in the mid-1900s led to severe polychlorinated biphenyl (PCB) contamination, which resulted in the harbor’s designation as a Superfund Site. Restrictions on the harvest of seafood from NBH have been in effect since 1979. Efforts to reduce the overall mass of PCBs in NBH by dredging PCB-contaminated sediments have been ongoing since the late 1980s. One goal of dredging is to reduce PCB concentrations in NBH seafood, monitored annually by Massachusetts Department of Environmental Protection (DEP) and Massachusetts Division of Marine Fisheries (MDMF). We used PCB concentrations in quahogs (2003-2016) and scup (2003-2014) to evaluate PCB distribution across seafood management areas and over time. Seafood PCB concentrations were used to evaluate improvements in environmental quality by examining total PCBs and patterns of PCB congeners within homolog groups, and by assessing human cancer risk from seafood consumption in the past (1980) and present (2012-2016). PCB concentrations in quahogs generally declined with increased time and distance from the PCB source, as does the cancer risk associated with their consumption. PCB concentrations in scup follow similar spatial patterns but show high annual variability. We conclude that quahogs are a reliable proxy for in-situ conditions, environmental quality, and human health risk.
Acoustic Measures of Prosody in Right-Hemisphere Damage: A Systematic Review and Meta-Analysis
Authors: Weed Ethan , Fusaroli Riccardo 
Published: June 2019

AbstractThe right hemisphere has often been claimed to be a locus for affective prosody, and people with right-hemisphere damage (RHD) have often been reported to show impairments in this domain. This phenomenon has been primarily investigated in terms of perception, more rarely in terms of production, and more rarely still using acoustic analysis. Our goal was to systematically review the papers reporting acoustic features of prosodic production in RHD, to identify strengths and weaknesses in this field, suggest guidelines for future research, and to support cumulative research by estimating the meta-analytic effect size of those features. We queried PubMed, PsychINFO, Web of Science, and Google Scholar, using the following combination of search terms: (prosody OR intonation OR inflection OR intensity OR pitch OR fundamental frequency OR speech rate OR voice quality) AND (RHD OR right hemisphere) AND (stroke) AND (acoustic). Standardized mean differences were extracted from all papers meeting inclusion criteria, and aggregated effect sizes were estimated using hierarchical Bayesian regression models. Sixteen papers met our inclusion criteria. We did not find strong evidence in the literature to indicate that the prosodic productions of people with RHD is substantially different from that of NBD controls, when measured in terms of acoustic features. However, the acoustic features of productions by people with RHD did differ from those of participants with NBD and LHD in some ways, notably in F0 variation and pause duration. Prosody type (emotional vs. linguistic) had very little effect. Taken together, currently available data show only a weak effect of RHD on prosody production. However, more accurate analyses are hindered by small sample sizes, lack of detail on lesion location, and divergent measuring techniques. Cumulative open science practices are recommended to overcome these issues.
Assembly of a persistent apical actin network by the formin Frl/Fmnl tunes epithelial cell deformability
Authors: Dehapiot Benoit , Clément Raphaël , Gazsó-Gerhát Gabriella , Philippe Jean-Marc , Lecuit Thomas 
Published: June 2019

AbstractTissue remodeling during embryogenesis is driven by the apical contractility of the epithelial cell cortex. This behavior arises notably from Rho1/Rok induced transient accumulation of non-muscle myosin II (MyoII pulses) pulling on actin filaments (F-Actin) of the medio-apical cortex. While recent studies begin to highlight the mechanisms governing the emergence of Rho1/Rok/MyoII pulsatility in different organisms, little is known about how the F-Actin organization influences this process. Focusing onDrosophilaectodermal cells during germband extension and amnioserosa cells during dorsal closure, we show that the medio-apical actomyosin cortex consists of two entangled F-Actin subpopulations. One exhibits pulsatile dynamics of actin polymerization in a Rho1 dependent manner. The other forms a persistent and homogeneous network independent of Rho1. We identify the Frl/Fmnl formin as a critical nucleator of the persistent network since modulating its level, in mutants or by overexpression, decreases or increases the network density. Absence of this network yields sparse connectivity affecting the homogeneous force transmission to the cell boundaries. This reduces the propagation range of contractile forces and results in tissue scale morphogenetic defects. Our work sheds new lights on how the F-Actin cortex offers multiple levels of regulation to affect epithelial cells dynamics.