bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antibiotic resistance and metabolic profiles as functional biomarkers that accurately predict the geographic origin of city metagenomics samples
Authors: Casimiro-Soriguer Carlos S. , Loucera Carlos , Florido Javier Perez , López-López Daniel , Dopazo Joaquin 
Published: November 2018

AbstractBackgroundThe availability of hundreds of city microbiome profiles allows the development of increasingly accurate predictors of the origin of a sample based on its microbiota composition. Typical microbiome studies involve the analysis of bacterial abundance profiles.ResultsHere we use a transformation of the conventional bacterial strain or gene abundance profiles to functional profiles that account for bacterial metabolism and other cell functionalities. These profiles are used as features for city classification in a machine learning algorithm that allows the extraction of the most relevant features for the classification.ConclusionsWe demonstrate here that the use of functional profiles not only predict accurately the most likely origin of a sample but also to provide an interesting functional point of view of the biogeography of the microbiota. Interestingly, we show how cities can be classified based on the observed profile of antibiotic resistances.
Beyond the seed: structural basis for supplementary microRNA targeting
Authors: Sheu-Gruttadauria Jessica , Xiao Yao , Gebert Luca F. R. , MacRae Ian J. 
Published: November 2018

AbstractmicroRNAs (miRNA) guide Argonaute proteins to mRNAs targeted for repression. Target recognition occurs primarily through the miRNA seed region, composed of guide (g) nucleotides g2–g8. However, nucleotides beyond the seed are also important for some known miRNA-target interactions. Here, we report the structure of human Argonaute2 (Ago2) engaged with a target RNA recognized through both miRNA seed and supplementary (g13–g16) regions. Ago2 creates a “supplementary chamber” that accommodates up to 5 miRNA-target base pairs. Seed and supplementary chambers are adjacent to each other, and can be bridged by an unstructured target loop of 1–15 nucleotides. Opening of the supplementary chamber may be constrained by tension in the miRNA 3' tail as increases in miRNA length stabilize supplementary interactions. Contrary to previous reports, we demonstrate optimal supplementary interactions can increase target affinity >20-fold. These results provide a mechanism for extended miRNA-targeting, suggest a function for 3' isomiRs in tuning miRNA targeting specificity, and indicate that supplementary interactions may contribute more to target recognition than is widely appreciated.
Construction of an index system for big data application in health care enterprises --A study based on the Delphi method
Authors: Chang Yue , Du Wei , Shi Ruo , Lei Tang , Zhou Hanni , Li Duan , Hu Jiaqi , Fan Xingyin 
Published: November 2018

AbstractThis study explored the theory of medical enterprise management and big data. Based on the Delphi method, two rounds of expert opinions were consulted on the capability of a health care enterprise big data application index system covering 11 dimensions, 46 first-level indicators and 111 second-level indicators. The index system includes two categories of input and capacity. The input category includes five dimensions: human resources, material resources, financial resources, government policies, and social service system or social environment. The capabilities category includes six dimensions: data integration capabilities, service capabilities, data analysis capabilities, information security, profitability, and innovation capabilities. This index system aims to appraise the application capability of big data scientifically and systematically, and fills the gaps of such research in China so far, which has positive significance for further research in the future.
Commentary on “diagnosis and treatment of ASD in women in secure and forensic hospital”
Authors: Chaplin Eddie , McCarthy Jane 
Published: November 2018

Purpose
The purpose of this paper is to provide a commentary on “diagnosis and treatment of asd in women in secure and forensic hospital”.

Design/methodology/approach
The approach is a commentary on a personal experience of services.

Findings
Women with ASD are often not diagnosed until adult years which may impact on their long-term outcomes. Secure services may not always have care teams who are appropriately trained to support a woman with ASD.

Originality/value
A commentary on an original viewpoint piece published in this special edition on women with autism spectrum disorder.
The regulatory power of standardized business processes
Authors: Reif Julia A.M. , Kugler Katharina G. , Brodbeck Felix C. 
Published: November 2018

Purpose
Managing business processes means establishing and maintaining their regulatory power, i.e., their capacity to guide and shape the practice of users and stakeholders. The purpose of this paper is to examine how the regulatory power of standardized business processes can be established and managed.

Design/methodology/approach
Building on a theory of standardization and on qualitative data, the authors suggest a “model of self-reinforcing business process management.”

Findings
Business process management consists of several phases (process design, process implementation, process application and process follow-up). A cyclical perspective on how these phases work together to create process legitimacy as presented in the model of self-reinforcing business process management can foster better understanding of the self-reinforcing dynamics of business process management.

Research limitations/implications
The paper offers starting points for interdisciplinary research on business process management. The proposed model should be further examined with regard to its usefulness for overcoming tensions and dynamics associated with standardization.

Practical implications
The model of self-reinforcing business process management provides a guideline for managers involved in planning, implementing, applying, or improving business processes or further areas of change-related organizational governance.

Originality/value
By modeling a cyclical sequence of business process management and highlighting the role of different kinds of legitimacy, the authors integrate functionalist and social perspectives on business process management in one model.
Share of voices in corporate social responsibility (CSR) news
Authors: Tam Lisa 
Published: November 2018

PurposeThe use of sources in news coverage affects news audience’s perceptions of news events. To extend existing research on inter media agenda-setting and agenda-building effects of CSR-related news, the purpose of this paper is to explore the representation and share of voices in CSR-related news by investigating and comparing the use of sources in press releases and news coverage.Design/methodology/approachThis study content-analyzed the 202 CSR-related press releases published by the two electricity providers in Hong Kong and 1,045 news articles related to the press releases over a five-year period. A total of 402 quotes from the press releases and 1,880 quotes from the news coverage were analyzed, including the types of sources cited, the tone of the sources and variations in the use of sources across seven different CSR themes.FindingsAlthough company representatives were quoted the most in both the press releases and news coverage, NGOs, government representatives and industry analysts were the most frequently cited for negative comments in the news coverage. Differences were found between the press releases and news coverage in terms of how frequently different sources were cited, the tone attributed to those sources, and the choice of sources across different CSR themes.Originality/valueThe findings reflect that corporations are not necessarily the most influential voice in CSR and that other groups also have their views represented in the news media. The representation of these voices differed by CSR themes. Corporations are advised to further explore what and how different voices are represented in the news coverage in relation to their CSR activities and to consider these voices when making decisions about CSR.
Longitudinal study of antecedents of work engagement in Thailand
Authors: Kunte Manjiri , RungRuang Parisa 
Published: November 2018

PurposeThe purpose of this paper is to examine the effects of job demands, job resources and personal resources on work engagement using the job demands–resources (JD–R) model.Design/methodology/approachThe study utilized a longitudinal research design in a sample of Thai employees (n=182). The data were collected by questionnaires administered in two waves over a period of four months, and the hypotheses were tested using hierarchical regression analysis.FindingsThe results supported the negative relationship between role ambiguity and work engagement. In addition, the findings suggested self-efficacy as a moderator in reducing the effect of increasing workload on work engagement.Research limitations/implicationsThe results of this study will be helpful for managers in designing appropriate human resources policies and practices; in recruiting, selecting and developing engaged employees; and in ensuring workplace well-being.Originality/valueThis is the first notable study establishing the applicability of the antecedents of work engagement in the JD–R model in a Thai work setting.
Electro-thermo-convection in dielectric liquid subjected to partial unipolar injection between two eccentric cylinders
Authors: Elkhazen Mohamed Issam , Hassen Walid , Öztop Hakan F. , Kolsi Lioua , Al-Rashed Abdullah A.A.A. , Borjini Mohamed Naceur , Ali Mohamed E. 
Published: November 2018

Purpose
The purpose of this work is to highlight the effects of partial unipolar injection on electro-thermo-convection (ETC) in dielectric liquid contained between two eccentric cylinders.

Design/methodology/approach
A finite volume method was used to solve governing equations. The study is performed for different parameters, such as radius ratio (0.2 ≤ Γ ≤ 0.6), dimensionless electric Rayleigh number (0 ≤ T ≤ 900), eccentricity (−0.4 ≤ e ≤ 0.4) and thermal Rayleigh number (10 ≤ Ra ≤ 5.105).

Findings
It is found that heat transfer increases with increase in dimensionless electric Rayleigh number and eccentricity ratio.

Originality/value
The originality of this work is to analyze the ETC in dielectric liquid subjected to partial unipolar injection between two eccentric cylinders
Do steering committees really steer?
Authors: McGrath Stephen Keith , Whitty Stephen Jonathan 
Published: November 2018

Purpose
The purpose of this paper is to investigate the confusion among project management practitioners about the role of steering committees.

Design/methodology/approach
Semi-structured interviews were conducted with highly experienced participants selected from a range of industries and disciplines in Queensland, Australia.

Findings
Six separate confusions on the role of steering committees were identified within that practitioner community. However, despite participants expressing various opposing views, they had actually come to the same working arrangements for their committees; all that was missing was a common conceptualisation of these working arrangements and consistent terminology.

Research limitations/implications
The paper provides clear evidence to the academic literature that confusion over the role of steering committees actually exists within the practitioner community and identifies six separate ways in which this occurs. It also identifies a problematic error in the widely used PRINCE2 governance model. Clarity in committee governance arrangements will facilitate future research endeavours through the removal of confusion surrounding committee labelling and accountability.

Practical implications
A committee decision tree model that guards against all six confusions is proposed for practitioner use, providing a means of avoiding unnecessary internal conflict within organisational governance arrangements. It can be used to check terms of reference of existing or proposed committees, facilitating organisational efficiency and effectiveness. The suggested renaming of project control groups to project coordination groups, and discontinuance of the practice of labelling committees that cannot authorise their decisions as either steering committees or boards, further supports this.

Social implications
Reconciliation of terminology with actual practice and the consequent clarity of governance arrangements can facilitate building social and physical systems and infrastructure, benefitting organisations, whether public, charitable or private.

Originality/value
Clarity regarding committee accountability can avoid confusion, misunderstanding and their consequent waste of time, resources and money.
Search effort and retail outcomes: the mediating role of search disconfirmation
Authors: Gillison Stephanie , Reynolds Kristy 
Published: November 2018

Purpose
The purpose of this paper is to investigate how shoppers’ expectations regarding the amount of search and disconfirmation of these search expectations affect outcomes of the shopping trip.

Design/methodology/approach
A survey of shoppers is used to test the proposed hypotheses.

Findings
Survey results indicate that search disconfirmation is conceptually distinct from but related to search effort and search regret. The results show that negative search disconfirmation mediates the relationship between search effort and shopper satisfaction, hedonic and utilitarian shopping value, choice confidence, search regret and negative word-of-mouth intent.

Originality/value
The findings underscore that search effort itself is not negative for shoppers. However, when search effort is perceived as excessive compared to shoppers’ expectations, negative retail outcomes can occur. Theoretical and managerial implications are discussed.
What initiatives do healthcare leaders agree are needed for healthcare system improvement? Results of a modified-Delphi study
Authors: Barson Stuart , Gauld Robin , Gray Jonathon , Henriks Goran , Krause Christina , Lachman Peter , Maher Lynne , Massoud M. Rashad , Mathias Lee , Wagner Mike , Villa Luis 
Published: November 2018

Purpose
The purpose of this paper is to identify five quality improvement initiatives for healthcare system leaders, produced by such leaders themselves, and to provide some guidance on how these could be implemented.

Design/methodology/approach
A multi-stage modified-Delphi process was used, blending the Delphi approach of iterative information collection, analysis and feedback, with the option for participants to revise their judgments.

Findings
The process reached consensus on five initiatives: change information privacy laws; overhaul professional training and work in the workplace; use co-design methods; contract for value and outcomes across health and social care; and use data from across the public and private sectors to improve equity for vulnerable populations and the sickest people.

Research limitations/implications
Information could not be gathered from all participants at each stage of the modified-Delphi process, and the participants did not include patients and families, potentially limiting the scope and nature of input.

Practical implications
The practical implications are a set of findings based on what leaders would bring to a decision-making table in an ideal world if given broad scope and capacity to make policy and organisational changes to improve healthcare systems.

Originality/value
This study adds to the literature a suite of recommendations for healthcare quality improvement, produced by a group of experienced healthcare system leaders from a range of contexts.
Selling the concept of brands: the Swedish advertising industry and branding in the 1920s
Authors: Åström Rudberg Elin 
Published: November 2018

PurposeThe purpose of the paper is to examine how the cartelized Swedish advertising industry contributed to the development of brands in Sweden in the early twentieth century. Specifically, a nationwide campaign for branded goods in 1925 is studied.Design/methodology/approachThe paper is based on a study of primary sources from the Swedish advertising agencies, manufacturers and retailers, which are analyzed using a hermeneutic method.FindingsThe paper shows that the unique organization of the main Swedish advertising agencies and the limited size of the market pushed the agencies into promoting and selling the idea of brands to consumers, retailers and manufacturers, which was done by exploiting established social sentiments in combination with American advertising techniques. It is also found that the Swedish advertising agencies described and conceptualized brands using widely known social ideals rather than the so-called brand personality aspect of branding.Research limitations/implicationsAlthough limited to the Swedish case, this paper suggests that research could benefit from taking different markets’ unique contexts into more consideration when studying the development of brands and advertising. In this paper, especially the organization and size of the advertising market together with the specific social and cultural values available to advertising professionals when creating brands, have been highlighted.Originality/valueThe paper emphasizes the size of the advertising market together with the organization of the advertising industry as important factors for the historical development of brands in Sweden. It also shows how brands were conceptualized using social ideals rather than the brand personality aspect of branding.
Cyberattacks on ships: a wicked problem approach
Authors: Mileski Joan , Clott Christopher , Galvao Cassia Bomer 
Published: November 2018

Purpose
The maritime industry is increasingly impacted by the Internet of things (IoT) through the automation of ships and port activities. This increased automation creates new security vulnerabilities for the maritime industry in cyberspace. Any obstruction in the global supply chain due to a cyberattack can cause catastrophic problems in the global economy. This paper aims to review automatic identification systems (AISs) aboard ships for cyber issues and weaknesses.

Design/methodology/approach
The authors do so by comparing the results of two receiver systems of the AIS in the Port of Houston; the JAMSS system aboard the Space Station and the “Harborlights” system for traffic control in the Port.

Findings
The authors find that inconsistent information is presented on the location of same ships at the same time in the Port. Upon further investigation with pilots, the authors find that these inconsistencies may be the result of the strength of power with which an AIS is transmitted. It appears the power may be reduced to the AIS in port but that it varies within port and varies by pilot operators. This practice may open the AIS system for tampering.

Originality/value
Further, this inconsistency may require further policy regulation to properly address cyber information in a port.
Experimental and numerical investigations of the vibration reliability of BGA and LGA solder configurations and SAC105 and 63Sn37Pb solder alloys
Authors: Gharaibeh Mohammad , Stewart Aaron J. , Su Quang T. , Pitarresi James M. 
Published: November 2018

Purpose
This paper aims to investigate and compare the reliability performance of land grid array (LGA) and ball grid array (BGA) solders, as well as the SAC105 and 63Sn37Pb solder alloys, in vibration loading conditions.

Design/methodology/approach
Reliability tests were conducted using a sine dwell with resonance tracking vibration experiment. Finite element simulations were performed to help in understanding the observed failure trends.

Findings
Reliability results showed that the tin-lead solders out-perform lead-free solders in vibrations loading. Additionally, the LGA solder type could provide a better vibration reliability performance than BGA solders. Failure analysis results showed that in LGAs, the crack is initiated at the printed circuit board side and at the component side in BGAs. In both types, the crack is propagated throughout in the intermetallic compound layer.

Originality/value
In literature, there is a lack of published data in the comparison between LGA and BGA reliability performance in vibration loadings. This paper provides useful insights in the vibration reliability behavior of the two common solder joint types.
Presence of Zearalenone in Cereal Grains and Its Exposure Risk Assessment in Indian Population
Authors: Rai Ankita , Dixit Sumita , Singh Sheelendra Pratap , Gautam Naveen Kumar , Das Mukul , Tripathi Anurag 
Published: November 2018

AbstractZearalenone (ZEA) is a toxic metabolite of Fusarium genera that frequently contaminates cereal grains. India being a tropical country provides suitable conditions for fungal invasion to the cereals. In the absence of any regulatory limits for ZEA in India, the present study was carried out to analyze the contamination levels of ZEA in different cereal samples consumed by Indian population and its exposure assessment through intake. Out of 117 cereal samples comprising of wheat, rice, corn, and oats, 70 (84%) were found to be positive for ZEA contamination, among which 24 (33%) samples exceeded the permissible limits proposed by European Union when analyzed by high‐performance liquid chromatography. The positive samples were further validated by Liquid Chromatography‐Mass Spectroscopy (LC‐MS) analysis. Based on the quantitative estimation of ZEA contamination in cereals and their daily consumption values, the probable daily intake of ZEA was found to be 16.9‐ and 7.9‐fold higher in rice and wheat samples, respectively, than the tolerable daily intake prescribed by European Food Safety Authority. The presence of ZEA at high levels indicates a higher exposure risk for Indian population as wheat and rice are staple foods in India. Thus, there is an immediate need to set the permissible levels of ZEA in India to safeguard the health of 1.34 billion people.Practical ApplicationHigh levels of ZEA contaminated wheat and rice samples suggest that the consumers are at a greater exposure risk. The study will help the Indian regulatory bodies to set the permissible level of ZEA in different cereal grains so as to safeguard the health of common masses. This can happen by simply adopting to European Food Safety Authority standards or depending on the consumption pattern of food and its occurrence, the new safe limit can be prescribed in India like in other Asian countries.