bluuebunny/crossref_metadata_2025_split huggingface dataset:
Obsessive-compulsive Disorder with Comorbid Bipolar Disorders: Clinical Features and Treatment Implications
Authors: Mucci Federico , Toni Cristina , Favaretto Ettore , Vannucchi Giulia , Marazziti Donatella , Perugi Giulio 
Published: January 2019

Background:Obsessive-compulsive disorder (OCD) symptoms within the context of a bipolar disorder (BD) have been described since the 19th century. Interestingly, the existence of a relevant overlap between the aforementioned psychiatric syndromes has been confirmed by a number of recent epidemiological and family studies.Aims:The aim of the present paper is to review the clinical features and the therapeutic implications of the OCD-BD comorbidity.Discussion:In the last two decades, the frequent association between OCD and BD has been earning a growing interest given its relevant nosological and therapeutic implications. Usually patients suffering from OCD-BD comorbidity show a peculiar clinical course, characterized by a larger number of concomitant depressive episodes and episodic course. In these cases, the treatment with antidepressants is more likely to elicit hypomanic or manic switches, while mood stabilizers significantly improve the overall clinical picture. Moreover, OCD-BD patients are frequently comorbid with a number of other psychiatric disorders, in particular anxiety disorders, social phobia, and different substance abuses, such as alcohol, nicotine, caffeine and sedatives.Conclusions:BD-OCD comorbidity needs further investigations in order to provide more solid evidences to give patients a more precise clinical diagnosis and a more targeted therapeutic approach.
Synthesis, Characterization and Biological Analysis of Some Novel Complexes of Phenyl Thiourea Derivatives with Copper
Authors: Mathur Neha , Jain Nisha , Sharma A.K. 
Published: January 2019

Introduction:
Copper is a very important metal because all forms of life require copper metals an essential micronutrient. Various biological processes, directly or indirectly are dependent on copper metal.

Methods:
Copper soaps are used as fungicides, bacteriosides, herbicides and insecticides. Copper complexes including heterocyclic compounds have attracted our attention in a magnificent way because of its utility in catalysis and biological functions. Their mechanism of synthesis, characterization and structural insight, are crucial for comprehending the criteria of the bonding and electronic interactions between the proximate metal center and chelating atoms. But still, there is a need to explore some of more biological properties for their wide applicability and significant usage in multiple fields because it is an untapped area with potentially tremendous value. Hence, in this paper, we report the synthesis and characterization of transition metal complex of N/S ligand by chromatographic, FT-IR, NMR, ESR, elemental analysis, conductometric and magnetic moment measurements.

Results:
The synthesized metal complexes namely copper palmitate with 4-nitrophenylthiourea and copper palmitate with 4-methoxyphenylthiourea were successfully investigated for biological activities against fungi Candida albicans and Trichoderma harzinum. Based on the results, we pronounced biocidal activities of the novel complexes.

Conclusion:
It is concluded that the activity of nitro phenylthiourea complex has greater antifungal activity than methoxy phenylthiourea complex against these test fungi. We can conclude that the antifungal activity of these complexes varies according to the nature of the groups attached to the ligands.
Should Viscous Fiber Supplements Be Considered in Diabetes Control? Results From a Systematic Review and Meta-analysis of Randomized Controlled Trials
Authors: Jovanovski Elena , Khayyat Rana , Zurbau Andreea , Komishon Allison , Mazhar Nourah , Sievenpiper John L. , Blanco Mejia Sonia , Ho Hoang Vi Thanh , Li Dandan , Jenkins Alexandra L. , Duvnjak Lea , Vuksan Vladimir 
Published: January 2019

OBJECTIVE
Evidence from randomized controlled trials (RCTs) suggests that viscous dietary fiber may offer beneficial effects on glycemic control and, thus, an improved cardiovascular disease risk profile. Our purpose was to conduct a systematic review and meta-analysis of RCTs to synthesize the therapeutic effect of viscous fiber supplementation on glycemic control in type 2 diabetes.

RESEARCH DESIGN AND METHODS
MEDLINE, Embase, and Cochrane Central Register of Controlled Trials were searched through 15 June 2018. We included RCTs ≥3 weeks in duration that assessed the effects of viscous fiber on markers of glycemic control in type 2 diabetes. Two independent reviewers extracted data. Data were pooled using the generic inverse variance method and expressed as mean differences (MD) with 95% CIs. Heterogeneity was assessed (Cochran Q statistic) and quantified (I2 statistic). The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was used to evaluate the overall certainty of the evidence.

RESULTS
We identified 28 eligible trial comparisons (n = 1,394). Viscous fiber at a median dose of ∼13.1 g/day significantly reduced HbA1c (MD −0.58% [95% CI −0.88, −0.28]; P = 0.0002), fasting blood glucose (MD −0.82 mmol/L [95% CI −1.32, −0.31]; P = 0.001), and HOMA-insulin resistance (IR) (MD −1.89 [95% CI −3.45, −0.33]; P = 0.02) compared with control and in addition to standard of care. The certainty of evidence was graded moderate for HbA1c, fasting glucose, fasting insulin, and HOMA-IR and low for fructosamine.

CONCLUSIONS
Viscous fiber supplements improve conventional markers of glycemic control beyond usual care and should be considered in the management of type 2 diabetes.
Long-term Absolute Risk for Cardiovascular Disease Stratified by Fasting Glucose Level
Authors: Bancks Michael P. , Ning Hongyan , Allen Norrina B. , Bertoni Alain G. , Carnethon Mercedes R. , Correa Adolfo , Echouffo-Tcheugui Justin B. , Lange Leslie A. , Lloyd-Jones Donald M. , Wilkins John T. 
Published: January 2019

OBJECTIVE
To estimate the long-term absolute risk for cardiovascular disease (CVD) according to fasting glucose (FG) levels below the threshold of diabetes.

RESEARCH DESIGN AND METHODS
We pooled data from seven observational cohorts of U.S. black and white men and women followed from 1960 to 2015. We categorized FG as follows: &lt;5.0, 5.0–5.5, 5.6–6.2, 6.3–6.9 mmol/L, and diabetes (FG ≥7.0 mmol/L or use of diabetes medications). CVD was defined as fatal/nonfatal coronary heart disease and fatal/nonfatal stroke. We estimated the risk of CVD by FG category at index age 55 years using a modified Kaplan-Meier survival analysis, adjusted for the competing risk of non-CVD death. We also assessed risk for incident CVD according to change in FG before 50 years of age, specifically among the categories &lt;5.6 mmol/L, 5.6–6.9 mmol/L, and diabetes.

RESULTS
Our sample included 19,630 individuals (6,197 blacks and 11,015 women) without a prior CVD event. Risk for CVD through 85 years of age ranged from 15.3% (&lt;5.0 mmol/L) to 38.6% (diabetes levels) among women and from 21.5% (5.0–5.5 mmol/L) to 47.7% (diabetes levels) among men. An FG of 6.3–6.9 mmol/L was associated with higher long-term CVD risk compared with the lowest FG among men but not women. Increases in glucose during midlife with conversion to diabetes were associated with higher cardiovascular risk (1.3- to 3.6-fold) than increases in glucose below the diabetes threshold.

CONCLUSIONS
Middle-age individuals with diabetes have high long-term absolute risk for CVD. These data strongly support the importance of blood glucose monitoring in midlife for CVD prevention.
Komparasi Hasil Belajar Materi Fluida Statis Melalui Penerapan Model Pembelajaran TPS Dan TPSQ Berbasis Advance Organizer Untuk Mengetahui Tingkat Pemahaman Konsep Peserta Didik Kelas XI SMA Negeri 1 Banda Aceh
Authors: Mustika Cut Rizki , Gani Abdul , Syukri Muhammad 
Published: January 2019

Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar fisika siswa melalui penerapan model pembelajaran think pair share dan think pair square berbasis strategi advance organizer pada konsep fluida statis serta mengetahui pengaruh strategi advance organizer terhadap pemahaman konsep peserta didik dalam menghubungkan materi sebelumnya dengan materi yang akan dipelajari. Metode penelitian yang digunakan adalah metode kuantitatif, dengan jenis penelitian quasi eksperimen. Populasi dalam penelitian ini ialah seluruh peserta didik kelas XI MIA SMA Negeri 1 Banda Aceh. Sampel dalam penelitian ini dipilih dengan teknik random sampling, yaitu peserta didik kelas XI MIA2 dan kelas XI MIA3 sebagai kelas eksperimen 1 dan 2. Pengumpulan data dilakukan dengan menggunakan tes hasil belajar sebanyak 10 soal berbentuk pilihan ganda. Data dianalisis dengan menggunakan uji-t. Hasil uji statistik data posttest untuk kelas eksperimen 1 dan 2 secara berturut diperoleh thitung = 0,29 dengan ttabel = 2,002, sehingga hipotesi Ho diterima dan disimpulkan bahwa terdapat perbedaan hasil belajar pemahaman konsep fisika peserta didik kelas XI MIA SMA Negeri 1 Banda Aceh melalui penerapan model pembelajaran TPS dan TPSQ berbasis advance organizer.
FAKTOR-FAKTOR PERTIMBANGAN PENERAPAN TEKNOLOGI PRECAST TERHADAP KINERJA PELAKSANAAN PROYEK KONSTRUKSI GEDUNG DI KOTA BANDA ACEH
Authors: Z Rusli , Afifuddin Mochammad , Rani Hafnidar Abd 
Published: January 2019

Abstract: This study aims to determine the factors to be considered in the application of precast technology in building construction projects in the city of Banda Aceh, and to analyze the relationship and influence between factors of consideration of the application of technology to the precast construction project implementation performance of buildings in Banda Aceh. This study uses a questionnaire distributed to the field of building construction company, ranging from qualifying M1, M2, and B1. The results showed that factors into consideration precast technology application in building construction projects in the city of Banda Aceh is a factor with a mean time of 4.179, with mean 4,172 quality considerations, cost considerations with a mean of 4.168 and 4.165 with mean special consideration. Relationship factors of consideration of the application of technology to the precast construction project implementation performance of buildings in Banda Aceh, all of them have a very high partially with Pearson correlation coefficient values between 0.800 to 1.00. Influence factors of consideration of the application of technology to the precast construction project implementation performance of buildings in Banda Aceh, the most influential factor is the consideration of time, with significant value 0.003 0.05. This suggests that if the consideration time factor is increased, then the performance of the project of construction of buildings in Banda Aceh will increase. Abstrak: Penelitian ini bertujuan untuk mengetahui faktor-faktor yang menjadi pertimbangan dalam penerapan teknologi precast pada proyek konstruksi gedung di Kota Banda Aceh, serta menganalisis hubungan dan pengaruh antara faktor-faktor pertimbangan penerapan teknologi precast terhadap kinerja pelaksanaan proyek konstruksi gedung di Kota Banda Aceh. Penelitian ini menggunakan kuesioner yang disebarkan kepada perusahaan kontraktor bidang gedung, mulai dari kualifikasi M1, M2, dan B1. Hasil penelitian menunjukkan bahwa faktor-faktor yang menjadi pertimbangan penerapan teknologi precast pada proyek konstruksi gedung di Kota Banda Aceh adalah faktor pertimbangan waktu dengan mean 4,179, pertimbangan mutu dengan mean 4,172, pertimbangan biaya dengan mean 4,168 dan pertimbangan khusus dengan mean 4,165. Hubungan faktor-faktor pertimbangan penerapan teknologi precast terhadap kinerja pelaksanaan proyek konstruksi gedung di Kota Banda Aceh, semuanya memiliki hubungan yang sangat tinggi secara parsial dengan nilai koefisien korelasi Pearson antara 0,800-1,00. Pengaruh faktor-faktor pertimbangan penerapan teknologi precast terhadap kinerja pelaksanaan proyek konstruksi gedung di Kota Banda Aceh, yang paling berpengaruh adalah faktor pertimbangan waktu, dengan nilai signifikansi 0,003 0,05. Hal ini menunjukkan bahwa apabila faktor pertimbangan waktu ditingkatkan, maka kinerja pelaksanaan proyek konstruksi gedung di Kota Banda Aceh akan semakin meningkat.
ANALISIS DINAMIS RIWAYAT WAKTU JEMBATAN GANTUNG AKIBAT PEJALAN KAKI DAN KENDARAAN RODA DUA
Authors: Edhi Sarwo , Hasan Muttaqin , Husaini Husaini 
Published: January 2019

Abstract : Suspended footbridges has a lot of constructed in Indonesia to access many–especially rural-regions. Due to its flexiblity, understanding and design of the suspension bridge is not enough to rely on static analysis. This paper deal with the dynamic behaviour of simply unstiffening suspended bridges subjected to pedestrian load and motor-cycles moving load.As the SNI 03-3428-1994 codeof the technical planning for pedestrian suspension bridge is not set in consideration of dynamic analysis and design,pedestrian-load model is based on British Standard BS 5400-4: 1990 and Eurocode EN1991-2:2003. Modeling pedestrian load is done in three conditions; single pedestrian, group, and crowd. The motor-cycles moving load is modeled as a moving force model, accurate for low speed. Variations in the speed used was 10 km / h, 20 km / h, 30 km / h are considered representative. Dynamic analysis done by the time history Newmark direct integration method with the help of finite element analysis program SAP2000 v.15. Span 60 m, 80 m and 100 m was studied. As these results, dynamic interaction between the bridges and pedestrian load is not significant.The analyses have shown that the responses greatly differ between the British Standard and Eurocode.However, motor-cycle load has same results but higher with the largest DAF value 7.27% for speeds of 30 km / h interval of 2 seconds on a span of 100 m. Abstrak: Jembatan gantung pejalan kaki telah banyak sekali dibangun di Indonesia, sebagai pemecah masalah akses antar wilayah. Dikarenakan strukturnya yang fleksible, pemahaman dan desain jembatan gantung tidak cukup sekedar mengandalkan analisis statis. Tujuan penelitian ini adalah untuk memperlihatkan respons dinamis jembatan gantung pejalan kaki sederhana tanpa pengaku. Hal yang akan dipelajari adalah simpangan vertikal dan percepatan ditinjau dari sisi kenyamanan. Beban yang dikenakan adalah beban pejalan kaki dan kendaraan roda dua. Dikarenakan SNI 03-3428-1994 Tata cara perencanaan teknik jembatan gantung untuk pejalan kaki tidak mengatur analisis dinamis dalam pertimbangan analisis dan desain, pemodelan beban pejalan kaki didasarkan pada British Standard BS 5400-4:1990 dan Eurocode EN1990. Pemodelan beban pejalan kaki dilakukan dalam tiga kondisi; pejalan tunggal, pejalan kelompok, dan arus keramaian. Untuk beban kendaraan dimodelkan sebagai beban berjalan yang cukup akurat untuk kecepatan rendah. Variasi kecepatan yang digunakan adalah 10 km/jam, 20 km/jam, 30 km/jam dianggap cukup representatif. Analisis dinamis dilakukan secara riwayat waktu dengan metode integrasi langsung Newmark dengan bantuan program analisa elemen hingga SAP2000 v.15. Bentang yang diteliti adalah 60 m, 80 m dan 100 m. Dari hasil tersebut didapati bahwa percepatan akibat beban pejalan kaki masih kecil sehingga tak berpengaruh secara signfikan. Sedangkan beban sepeda motor juga demikian, dengan nilai DAF terbesar 7,27 % untuk kecepatan 30 km/jam selang 2 detik pada bentang 100 m.
ANALISIS JARAK PEMATAH ARUS UNTUK MEMPERKECIL KECEPATAN ALIRAN PADA SISTEM DRAINASE JALAN
Authors: Yoga Padli , Saleh Sofyan M. , Yulianur Alfiansyah 
Published: January 2019

Abstract: The mountainous terrain with the road conditions on the slopes and the foot of the mountains that have a large service area and large slope of land when the rain of water overflows from the slopes of the mountains with a very large water debit flow and speed is high enough, the water flowing along the long road , resulting in disruption of traffic activity as well as damage to road construction and equipment. A large fold discharge and a high speed result in disruption of traffic activity and damage to road construction and equipment. This study aims to analyze the check dam spacing to minimize flow velocity to provide the required solution of road drainage in response to high flow velocity problems. The research used descriptive method for collecting secondary data and primary data as evaluation material, calculation refers to hydrology and hydraulics calculation system for open channel. The research was conducted on the road batas Kota Takengon-batas Bener Meriah. The results of the research obtained the average drainage flow velocity of 6,45 m/sec, the permit rate based on the material type 1.50 m/sec (does not meet the permit speed requirements), the drainage required installation xx. Average velocity after installation of upstream to downstream systems as a way to minimize a flow rate of 0,54 m/sec (meet the permission speed requirements). Abstrak: Medan bergunung dengan kondisi jalan yang berada di lereng dan kaki pegunungan yang mempunyai daerah layanan yang luas dan kemiringan lahan yang besar pada saat hujan air melimpah dari lereng pegunungan dengan debit air linpasan yang sangat besar serta kecepatan yang cukup tinggi, air mengalir mengikuti arah memanjang jalan, mengakibatkan terganggunya aktifitas lalulintas serta terjadinya kerusakan pada konstruksi jalan dan perlengkapannya. Debit linpasan yang besar serta kecepatan yang cukup tinggi mengakibatkan terganggunya aktifitas lalulintas dan terjadinya kerusakan pada konstruksi jalan dan perlengkapannya. Penelitian ini bertujuan menganalisis jarak pematah arus untuk memperkecil kecepatan aliran untuk memberikan solusi yang dibutuhkan drainase jalan raya dalam menanggulangi permasalahan kecepatan aliran yang tinggi. Penelitian mengunakan metode deskriptif untuk pengumpulan data sekunder dan data primer yang dijadikan sebagai bahan evaluasi, perhitungan mengacu pada sistem perhitungan hidrologi dan hidrolika untuk saluran terbuka. Penelitian dilakukan di ruas jalan batas Kota Takengon-batas Bener Meriah. Hasil dari penelitian didapat kecepatan aliran drainase rata-rata 6,45m/detik, kecepatan ijin berdasarkan jenis material 1,50 m/detik (tidak memenuhi persyaratan kecepatan ijin), drainase diperlukan pemasangan pematah arus. Kecepatan rata-rata setelah pemasangan pematah arus sitem jarak hulu ke hilir sebagai cara untuk memperkecil kecepatan aliran sebesar 0,56 m/detik (memenuhi persyaratan kecepatan ijin).
EVALUASI JARINGAN DAERAH IRIGASI BULOH BLANG ARA
Authors: Darsina Sri , Azmeri Azmeri , Syamsidik Syamsidik 
Published: January 2019

Abstract: Buloh Blang Ara Irrigation area includes in North Aceh District. The Location of D.I Buloh Blang Ara is located in DAS Buloh with the Total DAS is 25.60 km2. It is 9.15 % of total from WS Kr. Peusangan. The main river is Kr. Buloh with 5.97 lengths. Buloh Blang Ara Irrigation Area has 1,200 Hectares, 1,804 m primary channel length and 13,155 secondary channel lengths with some channel is land channel and some other is concrete channel,the intake is divided into two which are right intake and left intake. There is the water reduction supply which cause in the planting season, there is water shortage in DI. Buloh Blang Ara.This research aims to evaluate the network of Buloh Blan gAra Irrigation and to give the recommendations based on the study results obtained. The methodology used in the research is survey method and data analysis to determine the condition and function of irrigation networks.The network investigation shows that generally the network condition is good but only not well function because of the less of maintenance. Abstrak: Daerah Irigasi Buloh Blang Ara termasuk dalam wilayah Kabupaten Aceh Utara. Lokasi D.I Buloh Blang Ara terletak di dalam DAS Buloh dengan luas DAS 25,60 km2, memiliki persentase sebesar 9,15 % dari total luas keseluruhan WS. Kr. Peusangan. Sungai Utama pada DAS tersebut adalah Kr. Buloh dengan panjang sungai 5,97 km. Daerah Irigasi Buloh Blang Ara dengan luas areal 1200 Ha, memiliki panjang saluran induk sepanjang 1.804 m dan saluran sekunder sepanjang 13.155 m dengan kondisi saluran sebagian tanah dan sebagian beton,intake terbagi dua yaitu intake kanan dan intake kiri. Saat ini terjadi penurunan layanan suplai air sehingga pada setiap musim tanam areal yang ada pada Daerah Irigasi Buloh Blang Ara kekurangan air. Tujuan dari penelitian ini adalah : mengevaluasi jaringan irigasi Buloh Blang Ara dan memberi rekomendasi berdasarkan hasil yang diperoleh dari hasil studi. Metode yang digunakan pada penelitian ini adalah metode survei dan analisis data untuk mengetahui kondisi dan fungsi jaringan irigasi. Penelusuran jaringan menunjukkan bahwa kondisi saluran pada umumnya dalam keadaan baik , hanya saja tidak lagi berfungsi sebagaimana mestinya karena kurangnya pemeliharaan.
EVALUASI KINERJA JARINGAN DRAINASE GAMPONG KUTA ATEUH BERDASARKAN KAPASITAS SALURAN TERHADAP PENATAAN RUANG KOTA SABANG
Authors: Zulaini Liza , Yulianur Alfiansyah , Fatimah Eldina 
Published: January 2019

Abstract: Gampong Kuta Ateuh is the center of settlement and government office areas concerned to guard its territory against flooding inundation, so it is necessary a representative drainage handling. The purpose of this research is to evaluate the performance of drainage network of Gampong Kuta Ateuh based on channel capacity on existing spatial condition, and to evaluate the performance of drainage network based on channel capacity on Sabang City Spatial Condition. Based on the result of performance evaluation of drainage network at Gampong Kuta Ateuh on existing spatial condition based on channel capacity obtained 2 (two) unsafe channel segment which yield minus value (-) for Qs-QT. Based on spatial arrangement that is at least the proportion of 30% RTH (Green Open Space) of each DTH produces 5 (five) unsecured channel segments, this shows current RTH Kota Sabang 30%. A value of the runoff coefficient (C) has a range between 0,5453 and 0,5025. Spatial arrangement of this research has resulted in many channels damaged by the arrangement of road landscapes that do not follow the Ministerial Decree No.05 / PRT / M / 2012 on Tree Planting Guidance on Road Network Systems. The path of plant on the road should be placed on the edge of traffic lane and pedestrian path, after the pedestrian path then the channel. Abstrak: Gampong Kuta Ateuh merupakan pusat permukiman dan kawasan perkantoran pemerintah yang berkepentingan untuk menjaga wilayahnya terhadap banjir genangan sehingga perlu penanganan drainase yang representatif. Tujuan dari penelitian ini adalah mengevaluasi kinerja jaringan drainase Gampong Kuta Ateuh berdasarkan kapasitas saluran terhadap kondisi tata ruang existing, dan mengevaluasi kinerja jaringan drainase berdasarkan kapasitas saluran terhadap kondisi Penataan Ruang Kota Sabang. Berdasarkan hasil evaluasi kinerja jaringan drainase Gampong Kuta Ateuh pada kondisi tata ruang existing berdasarkan kapasitas saluran diperoleh 2 (dua) ruas saluran yang tidak aman dimana menghasilkan nilai minus (-) untuk Qs-QT. Berdasarkan penataan ruang yaitu minimal proporsi 30% RTH (Ruang Terbuka Hijau) dari tiap DTH menghasilkan 5 (lima) ruas saluran yang tidak aman, hal ini menunjukkan saat ini RTH Kota Sabang 30%. Nilai Koefisien aliran (C) berdasarkan penataan ruang saat ini adalah paling tinggi 0,5453 sedangkan berdasarkan penataan ruang dengan proporsi minimal RTH 30% adalah 0,5025. Penataan ruang dari penelitian ini menghasilkan bahwa banyak saluran yang rusak akibat penataan lanskap jalan yang tidak mengikuti Permen PU No.05/PRT/M/2012 tentang Pedoman Penanaman Pohon pada Sistem Jaringan Jalan. Jalur tanaman pada jalan sebaiknya diletakkan ditepi jalur lalu lintas, yaitu diantara jalur lalu lintas kendaraan dan jalur pejalan kaki. Setelah jalur pejalan kaki kemudian saluran.