bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of Sediment Accumulation Model for Trunk Sewer Using Multiple Linear Regression and Neural Network Techniques
Authors: Al-Ani Rami Raad Ahmed , Al-Obaidi Basim Hussein Khudair 
Published: January 2019

Sewer sediment deposition is an important aspect as it relates to several operational and environmental problems. It concerns municipalities as it affects the sewer system and contributes to sewer failure which has a catastrophic effect if happened in trunks or interceptors. Sewer rehabilitation is a costly process and complex in terms of choosing the method of rehabilitation and individual sewers to be rehabilitated. For such a complex process, inspection techniques assist in the decision-making process; though, it may add to the total expenditure of the project as it requires special tools and trained personnel. For developing countries, Inspection could prohibit the rehabilitation proceeds. In this study, the researchers proposed an alternative method for sewer sediment accumulation calculation using predictive models harnessing multiple linear regression model (MLRM) and artificial neural network (ANN). AL-Thawra trunk sewer in Baghdad city is selected as a case study area; data from a survey done on this trunk is used in the modeling process. Results showed that MLRM is acceptable, with an adjusted coefficient of determination (adj. R2) in order of 89.55%. ANN model found to be practical with R2 of 82.3% and fit the data better throughout its range. Sensitivity analysis showed that the flow is the most influential parameter on the depth of sediment deposition.
The Turin Papyrus Online Platform (TPOP): An Introduction
Authors: Töpfer Susanne 
Published: January 2019

In recent years, scholarly communities as well as the general public have been increasingly requesting open access to museum collections, prompting institutions to offer online catalogues, mostly of selected objects, in some cases even of their complete collections. Major Egyptian papyrus collections, however, have so far been extremely slow in adopting this open-access approach. Until recently, this was also true of the Museo Egizio in Turin, which houses one of the largest collections of Egyptian antiquities worldwide.
The TPOP project aims to conserve, document, digitize and contextualize hundreds of papyrus manuscripts and thousands of fragments in a newly created online platform. This platform will enable scholars to work collaboratively on the material and will provide a straightforward publication outlet for both the scholarly and the general public. It aims to generate value beyond the mere preservation of material culture. The virtual “restoration” of papyri by digitally reconstructing them and joining fragments online makes possible what physical restoration does not allow, namely, the long-term preservation of written cultural heritage and its accessibility by anyone from anywhere and at any time.
ملخص البحث:
طلبت المجتمعات الأكاديمية وعامة الناس في السنوات الأخيرة الوصول بحرية إلى المجموعات الخاصة بالمتاحف، مما دفع المؤسسات إلى توفير كتالوجات على الإنترنت معظمها خاصة بعناصر منتقاة لدرجة أن بعضها يعرض المجموعات الكاملة لتلك العناصر في بعض الحالات. على الرغم من ذلك، فإن مجموعات ورق البردي المصرية الرئيسية بطيئة للغاية حتى الآن في تبني نهج الوصول الحر إليها. وهذا ينطبق أيضًا على المتحف المصري في تورينو حتى وقت قريب، والذي يضم واحدة من أكبر مجموعات الآثار المصرية في جميع أنحاء العالم.
يهدف مشروع قاعدة بيانات البردي عبر الإنترنت في تورينو "TPOP" إلى حفظ المئات من مخطوطات البردي وآلاف الأجزاء الممزقة وتوثيقها ورقمنتها وفهم سياقها في منصة إلكترونية تم إنشاؤها حديثًا. ستعمل هذه المنصة على تمكين الأكاديميين من العمل بشكل تعاوني على المواد وستوفر منفذًا مباشرًا للمطبوعات لكل من الأكاديميين والعامة. ويهدف المشروع إلى إنشاء قيمة أكبر من مجرد الحفاظ على الثقافة المادية. حيث أنه من شأن "الترميم" الافتراضي للبرديات من خلال إعادة تكوينها رقمياً وجمع أجزاءها عبر الإنترنت أن يجعل ما لم يستطع الترميم المادي توفيره ممكنًا، وهو الحفاظ على التراث الثقافي المكتوب على المدى الطويل وإمكانية الوصول إليه من قبل أي شخص من أي مكان وفي أي وقت.
Crescimento e produtividade de linhaça
Authors: Stanck Luciane Teixeira , Becker Dislaine , Bosco Leosane Cristina 
Published: January 2019

O Sul do Brasil tem potencialidades edafoclimáticas para o cultivo de linhaça, no entanto faltam estudos básicos para caracterizar o crescimento e produtividade dessa cultura. O objetivo do trabalho foi caracterizar o crescimento e a produtividade de linhaça nas condições edafoclimáticas de Curitibanos, SC. Os experimentos foram desenvolvidos na área experimental da UFSC/Curitibanos, nos anos de 2014 e 2015. O delineamento utilizado foi em blocos ao acaso, com dois tratamentos e quatro blocos. Para realização das análises de crescimento das plantas de linhaça, plantas foram marcadas, com arames coloridos. Semanalmente, foram realizadas avaliações de contagem do número de folhas da haste principal e medida a estatura de plantas. A determinação da massa seca foi realizada em intervalos quinzenais. A produtividade foi avaliada após a colheita de plantas de cada unidade experimental através da contagem de número de cápsulas da haste principal, do número de sementes por cápsula e da massa de mil sementes. A partir disso estimou-se a produtividade por área de cultivo (t ha-1). Os dados meteorológicos para caracterização de cada ano de cultivo foram obtidos de uma estação meteorológica automática localizada próxima ao experimento. A evolução da estatura, número de folhas e massa seca da linhaça ao longo do tempo de cultivo é similar entre os genótipos de linhaça marrom e dourada. Em média a estatura final das plantas é de 82,6 cm, o número final de folhas é 101 e a massa seca é 6,7g/planta. O ano de cultivo influencia o crescimento e a produtividade de linhaça.
Edukasi pasien chronic kidney disease berbasis aplikasi android : buku saku pasien
Authors: Relawati Ambar , Syafriati Ani , Al Hasbi Habid , Fitria Pipit Nur 
Published: January 2019

This educational innovation follows the development of the times, where mobile phones become the main electronic tool in the wider community. Researchers develop these innovations by providing general education about chronic kidney failure, nutritional diet and fluid restrictions packed inside an android app. It aims to allow patients to easily access information about chronic renal failure in an increasingly sophisticated technological era. In addition to the information, researchers Â also added some additional menus or features of the profile, calculator GFR, daily reminder, UF recordings that help patients to facilitate the recording on the phone. Educational counseling android-based applications for two days ie 15-16 January 2018 in the Hemodialisa unit PKU Muhammadiyah Gamping Hospital. Respondents were given education as many as 30 people. The results of the pre and post test questionnaires were processed using SPSS version 16 with Wilcoxon's pre-post test nonparametics. Based on the results obtained for pre and post test of p value 0,000. Applications android Pocket Book Patient This dialysis provides benefits and improves the knowledge of patients who run dialysis in a modern way and easy to access both patients and families.
Prevalence of Iron Deficiency Anemia in Anemic Patients: A Hospital Based Study
Authors: Mishra Satyendra Kumar , Marasini Surendra , Gupta Badri Kumar , Agrawal Krishna Kumar , Gautam Narayan 
Published: January 2019

Introduction: In developing countries like Nepal, iron deficiency anemia (IDA) is one of the major concern. The high rate incidence has been related to insufficient iron intake, accompanied by chronic intestinal blood loss due to parasitic and malarial infections. Therefore, a study was conducted to evaluate the prevalence of IDA in anemic patients of Universal College of Medical Sciences-Teaching Hospital (UCMS-TH), South Western region, Nepal.
Material and Method It was a hospital based cross sectional study comprised of 100 anemic patients. Their detailed medical history and lab investigations, focusing on hematological parameters were documented. Peripheral smear examination and serum ferritin estimation were done to observe red cell morphology and iron status respectively.
Results: This study revealed that out of 100 anemic patients, 35% were that of IDA. The most affected age group was 21-40 years with frequency 42.55%. IDA was more common in females (42.85%) than in male (21.62%). Out of 100 anemic patients, microcytic hypochromic anemia was predominant in 47% followed by macrocytic anemia (31%) and then normocytic normochromic anemia (22%). Out of 47 microcytic hypochromic anemic patients, 12 had normal serum ferritin. There was a statistical significant difference in Hb (p=0.011), MCV (p=0.0001), MCH (p=0.0001), MCHC (p=0.0001) and serum ferritin (p=0.0001) among all types of anemia. There was a statistical significant positive correlation of ferritin with Hemoglobin (0.257, p= 0.01), MCV (0.772, p= 0.0001), MCH (0.741, p=0.0001) and MCHC (0.494, p=0.0001).
Conclusion: The peripheral smear in conjunction with serum ferritin estimation needs to be included for susceptible individuals to screen the IDA and other types of anemia.
Misoprostol Versus Oxytocin for Induction of Labour at Term and Post Term Pregnancy of Primigravida
Authors: Tripathi Malati , Adhikari Ayushma , Neupane Bibhushan 
Published: January 2019

Introduction: To compare effectiveness and safety of sublingually administered misoprostol and intravenously infused 10 units of oxytocin for labor induction at term and post term pregnant women in Gandaki Medical College Teaching Hospital (GMCTH).
Materials and methods: This is a prospective study conducted in Department of Obstetrics and Gynaecology in Gandaki Medical College and performed on 120 patients of primigravida with cephalic presentation at term and post-term pregnancy. Patients were given 50µg sublingual misoprostol 6 hourly (two doses) and 5 units of oxytocin in 500ml RL started from 10 drops up to 60 drops till effective contraction occur with maximum of 10 units oxytocin. Maternal and fetal outcomes were observed. Collected data were analyzed using SPSS and MS Excel.
Results: There were no significant differences between the groups concerning time duration between inductions to delivery time, indications of caesarean section, different modes of delivery and for the Apgar score at one and five minutes.
Conclusion: Both oxytocin and misoprostol are effective and safe for induction of labour.
Immune Checkpoint B7x (B7-H4/B7S1/VTCN1) is Over Expressed in Spontaneous Canine Bladder Cancer: The First Report and its Implications in a Preclinical Model
Authors: Chand Damini , Dhawan Deepika , Sankin Alexander , Ren Xiaoxin , Lin Juan , Schoenberg Mark , Knapp Deborah W. , Zang Xingxing 
Published: February 2019

Background: B7x (B7-H4/B7S1/VTCN1), an inhibitory immune checkpoint molecule is a potential therapeutic target owing to its immunosuppressive effect and well-known expression in cancers. Immune checkpoints in canine bladder cancer are largely undefined. Here, we report the first evaluation on expression of B7x in spontaneous canine invasive bladder cancer, a novel model system for the study of invasive human urothelial carcinoma. Objective: This work aims to study expression of immune checkpoint B7x in spontaneous canine invasive bladder cancer. Methods: RNA-seq analysis was performed to determine B7x expression in tumor versus normal bladder. Gene ontology (GO) study was used to explore the biological role of B7x. B7x protein expression was evaluated by immunohistochemistry (IHC). TCGA and GTEx were used to examine B7x expression in 599 human bladder urothelial carcinoma (BLCA). Results: RNA-seq analysis indicated 5.72 and 7.04 fold up regulation of B7x in tumors, using DESeq2 and edge R respectively ( p < 0.00008). B7x was closely associated with immune processes in GO analysis. IHC results revealed 60% of cases as B7x positive. B7x intensity was scored as negative in 40% ( n = 20/50), low in 24% ( n = 12/50), medium in 14% ( n = 7/50) and high in 22% ( n = 11/50) of cases. In human BLCA, B7x expression was significantly associated with worse overall survival ( p = 0.02). Conclusions: Our results suggest that B7x is over expressed in canine bladder cancer. Thus canine model can be vital in advancing the translational research on B7x, a new potential therapeutic target in human bladder cancer.
Comparación de la resistencia de comprensión en maderas nativas
Authors: Sánchez Yorlenis , Gallardo Álvaro , Delgado Rodney 
Published: January 2019

El ensayo de compresión en un material consiste en una fuerza que se ejerce sobre un cuerpo para disminuir su
volumen y medir su resistencia máxima a la deformación. En esta investigación se presenta un estudio sobre el comportamiento de seis especies diferentes de árboles maderables existentes en Panamá a ser sometidos al esfuerzo de compresión paralela a las fibras, con el objetivo de determinar cuál es la especie con mayor resistencia a este tipo esfuerzo basándonos en ciertas características tales como la densidad y su contenido de humedad.
Para efectuar estos ensayos fue imprescindible la elaboración de seis probetas para cada especie a estudiar y apoyándonos en la norma americana ASTM-D143, logramos fijar las dimensiones mínimas necesarias para realizar el ensayo a compresión paralela a las fibras.
Entre las especies que estudiamos están las siguientes: Roble, Cedro Amargo, Laurel, Corotú, Velario y Amarillo.
Developing Students’ Motivation at MTS Negeri Papi Enrekang in Speaking English through Selected Games
Authors: Jabri Umiyati 
Published: February 2019

This research aimed at finding whether the students were motivated to speak English by using communication games and also finding out students’ part. The sample consisted of 30 students in participation in the classroom. In this reaserch the data were obtained through questionnaire (one and two). The result of the questionnaire’s description showed that the motivation of students was positive. It can be concluded that students are motivated to learn English through communication games. It was proved from the findings the of the students’ averange score that was 89.6 and the mean score was 4.48. The level of motivation was considered very high based on Likert Scale, and the result of the Questionnaire preference showed that the students prefer jigsaw as communication games in speaking English with percentage, Jigsaw (56.7%), Giving Direction (33.3%), and Picture Pairs (10%).
Komposisi Jenis Dan Zonasi Mangrove Di Kampung Gisim Kabupaten Sorong
Authors: Nanlohy Lona Helty , Maruapey Azis , Malaum Yolanda 
Published: January 2019

Komposisi jenis merupakan formasiÂ jenis yang berada pada suatu tempat. Penyebaran vegetasi mangrove membentuk bentukÂ khas yaitu membentukÂ zonasi sejajar garis pantai. Terdapat zonasiÂ mangrove tertentu dari mulai arah pantai ke darat. Hal yang menarik adalah bahwa jenis-jenis mangrove yang menempati zona-zona tersebut tidak selalu sama untuk setiap daerah yang diteliti. Hal ini menunjukan adanya banyak faktor yang mengendalikan zonasi vegetasi mangrove.Metode penelitianÂ yang digunakan adalah penelitianÂ survey, dengan teknikÂ sampling sistematik menggunakan metode kombinasi antara metoda jalur dan metoda garis berpetak.Komposisi jenis mengrove di Kampung Gisim Kabupaten Sorong terdiri dari mangrove mayor (mangrove sejati)Â sebanyak 5 jenis yaitu Rhizophora mucronata, Bruguiera gymnorrhiza,Â Bruguiera sexangula, Â Â Ceriops TagalÂ dan Â Nypa fruticans dan MangroveÂ minorÂ yaitu jenis Xylocarpus granatum. Zonasi pada lokasi penelitian secara umum dibagi menjadi 3 zona, yaitu : zona proximal, zona midle, dan zona distal.Â Zona proximal merupakan zona yang berbatasan langsung dengan laut dan merupakan zona dari jenis Rhizophora mucronataÂ Zona midle adalah zona pertengahan yang terletak diantara darat dan laut, jenis yang berada zona yaituÂ jenisÂ Bruguiera sexangulaÂ Bruguiera gymnorrhiza. Ceriops Tagal dan Xylocarpus granatum dan Zona distal adalah zona yang berada dibelakang zona middleÂ yaitu jenisÂ Nypa fruticans.
PENGARUH PEMBERIAN JENIS PUPUK ORGANIK BOKASHI TERHADAP PRODUKSI TANAMAN JAGUNG MANIS ( Zea mays saccarata Lin.)
Authors: Homer Vilipus , Ali Akhmad , Maruapey Ajang 
Published: January 2019

Penelitian bertujuan untuk mengetahuiÂ Â pengaruhÂ pemberian 3 jenis pupukÂ organik bokashiÂ terhadap Â dan produksi danÂ untuk mengethaui salah satu jenis pupuk organik bokashi yang memberikan pengaruh terhadap Â produksiÂ tanaman jagung manis (Zea maysÂ Saccarata Lin)Penelitian berlangsung mulai dari bulan Juni sampai dengan bulan September pada tahun 2016 dalam bentuk percobaan rancangan Acak kelompok (RAK),4 kali perlakuan : Po= Kontrol, P1= 10 ton bokasi kotoran sapi =3,6 kg/petak, P2= 10 ton kotoran Ayam =3,6 kg/petak, P3= 10 ton Jerami padi = 3,6 kg/petak. Setiap perlakuan diulang 3 kali sehingga mendapatkan 12 satuan petak perlakuan percobaan.Setiap petak percobaan terdapat 25 tanaman dengan jarak tanam 70x20 cmdengan ukuran 1.2 meter x 3 meter. Dan jumlah seluruh tanaman yang didapat dalam percobaan 300 tanaman sampel.Â Â Â Â Dilakukan dengan menggunakan Pupuk Organik bokasi Kotoran sapi, ayam dan jerami padi, yang mana organik bokasi sapi 3,6 kg/petak, menghasilkan tanaman Jagung manis lebih baik dan mencapai Produksinya tornggol Jagung manisÂ terberat (125,75 g) serta produksi tanaman jagung Manis tertinggi (Zea mays saccarata) 17,11/ha.Â
A 1000 au Scale Molecular Outflow Driven by a Protostar with an Age of ≲4000 yr
Authors: Furuya Ray S. , Kitamura Yoshimi , Shinnaga Hiroko 
Published: January 2019

Abstract
To shed light on the early phase of a low-mass protostar formation process, we conducted interferometric observations toward protostar GF 9-2 using the CARMA and SMA. The observations were carried out in the 12CO

line and the continuum emission at wavelengths of 3.3 mm, 1.1 mm, and 850 μm with a spatial resolution of ≈400 au. All of the continuum images detected a single point-like source with a beam-deconvolved effective radius of 250 ± 80 au at the center of the previously known 1.1–4.5

molecular cloud core. Compact emission is detected toward the object at the Spitzer MIPS and IRAC bands, as well as the four bands at the Wide-field Infrared Survey Explorer. Our spectroscopic imaging of the CO line revealed that the continuum source is driving a 1000 au scale molecular outflow, including a pair of lobes where a collimated “higher”-velocity (∼10

with respect to the velocity of the cloud) red lobe exists inside a poorly collimated “lower”-velocity (∼5

) red lobe. These lobes are rather young (dynamical timescales of ∼500–2000 yr) and the least powerful (momentum rates of

yr−1 ) ones so far detected. A protostellar mass of

was estimated using an upper limit of the protostellar age of τ
* ≲ (4 ± 1) × 103 yr and an inferred nonspherical steady mass accretion rate of ∼1 × 10−5

yr−1. Together with the results from an SED analysis, we discuss that the outflow system is driven by a protostar with a surface temperature of ∼3000 K, and that the natal cloud core is being dispersed by the outflow.
A Hot Ultraviolet Flare on the M Dwarf Star GJ 674
Authors: Froning Cynthia S. , Kowalski Adam , France Kevin , Loyd R. O. Parke , Schneider P. Christian , Youngblood Allison , Wilson David , Brown Alexander , Berta-Thompson Zachory , Pineda J. Sebastian , Linsky Jeffrey , Rugheimer Sarah , Miguel Yamila 
Published: January 2019

Abstract
As part of the Mega-Measurements of the Ultraviolet Spectral Characteristics of Low-Mass Exoplanetary Systems Hubble Space Telescope (HST) Treasury program, we obtained time-series ultraviolet spectroscopy of the M2.5V star, GJ 674. During the far-ultraviolet (FUV) monitoring observations, the target exhibited several small flares and one large flare (E
FUV = 1030.75 erg) that persisted over the entirety of an HST orbit and had an equivalent duration >30,000 s, comparable to the highest relative amplitude event previously recorded in the FUV. The flare spectrum exhibited enhanced line emission from chromospheric, transition region, and coronal transitions and a blue FUV continuum with an unprecedented color temperature of TC
≃ 40,000 ± 10,000 K. In this Letter, we compare the flare FUV continuum emission with parameterizations of radiative hydrodynamic model atmospheres of M star flares. We find that the observed flare continuum can be reproduced using flare models but only with the ad hoc addition of a hot, dense emitting component. This observation demonstrates that flares with hot FUV continuum temperatures and significant extreme-ultraviolet/FUV energy deposition will continue to be of importance to exoplanet atmospheric chemistry and heating, even as the host M dwarfs age beyond their most active evolutionary phases.
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
Authors: Chellappa Stalin , Kushekhar Kushi , Munthe Ludvig A. , Tjønnfjord Geir E. , Aandahl Einar M. , Okkenhaug Klaus , Taskén Kjetil 
Published: January 2019

AbstractIn chronic lymphocytic leukemia (CLL), signaling through several prosurvival B cell surface receptors activates the PI3K signaling pathway. Idelalisib is a highly selective PI3K (PI3Kδ) isoform-specific inhibitor effective in relapsed/refractory CLL and follicular lymphoma. However, severe autoimmune adverse effects in association with the use of idelalisib in the treatment of CLL, particularly as a first-line therapy, gave indications that idelalisib may preferentially target the suppressive function of regulatory T cells (Tregs). On this background, we examined the effect of idelalisib on the function of human Tregs ex vivo with respect to proliferation, TCR signaling, phenotype, and suppressive function. Our results show that human Tregs are highly susceptible to PI3Kδ inactivation using idelalisib compared with CD4+ and CD8+ effector T cells (Teffs) as evident from effects on anti-CD3/CD28/CD2–induced proliferation (order of susceptibility [IC50]: Treg [.5 μM] &gt; CD4+ Teff [2.0 μM] &gt; CD8+ Teff [6.5 μM]) and acting at the level of AKT and NF-κB phosphorylation. Moreover, idelalisib treatment of Tregs altered their phenotype and reduced their suppressive function against CD4+ and CD8+ Teffs. Phenotyping Tregs from CLL patients treated with idelalisib supported our in vitro findings. Collectively, our data show that human Tregs are more dependent on PI3Kδ-mediated signaling compared with CD4+ and CD8+ Teffs. This Treg-preferential effect could explain why idelalisib produces adverse autoimmune effects by breaking Treg-mediated tolerance. However, balancing effects on Treg sensitivity versus CD8+ Teff insensitivity to idelalisib could still potentially be exploited to enhance inherent antitumor immune responses in patients.