bluuebunny/crossref_metadata_2025_split huggingface dataset:
“God Never Appeared to Moses:” Eusebius of Caesarea’s Peculiar Exegesis of the Burning Bush Theophany
Authors: Bucur Bogdan G. 
Published: December 2018

AbstractThe exegesis of the burning bush theophany set forth in Eusebius of Caesarea’s Prophetic Extracts and Proof of the Gospel adds a distinctive and original voice to the rich chorus of Jewish and Christian interpreters of Exodus 3. Eusebius posits a disjunction between the visual and the auditory aspects of the theophany – the angel appears, the Lord speaks – and departs from the mainstream of Jewish and Christian tradition by depicting Moses as a spiritual neophyte whose attunement to God ranks much lower than that of the patriarchs of old. Even though scholars point to the overall anti-Jewish context of this exegesis, it is difficult to find satisfactory terms of comparison for some of its details. It appears, therefore, that Eusebius’ understudied Prophetic Extracts and Proof of the Gospel offer a surprisingly original interpretation that should enrich the scholarly account of theWirkungsgeschichteof the famous burning bush episode.
Molecular Relationships between Bronchial Asthma and Hypertension as Comorbid Diseases
Authors: Bragina Elena Yu. , Goncharova Irina A. , Garaeva Anna F. , Nemerov Evgeniy V. , Babovskaya Anastasija A. , Karpov Andrey B. , Semenova Yulia V. , Zhalsanova Irina Z. , Gomboeva Densema E. , Saik Olga V. , Zolotareva Olga I. , Ivanisenko Vladimir A. , Dosenko Victor E. , Hofestaedt Ralf , Freidin Maxim B. 
Published: December 2018

AbstractComorbidity, a co-incidence of several disorders in an individual, is a common phenomenon. Their development is governed by multiple factors, including genetic variation. The current study was set up to look at associations between isolated and comorbid diseases of bronchial asthma and hypertension, on one hand, and single nucleotide polymorphisms associated with regulation of gene expression (eQTL), on the other hand. A total of 96 eQTL SNPs were genotyped in 587 Russian individuals. Bronchial asthma alone was found to be associated with rs1927914 (TLR4), rs1928298 (intergenic variant), and rs1980616 (SERPINA1); hypertension alone was found to be associated with rs11065987 (intergenic variant); rs2284033 (IL2RB), rs11191582 (NT5C2), and rs11669386 (CARD8); comorbidity between asthma and hypertension was found to be associated with rs1010461 (ANG/RNASE4), rs7038716, rs7026297 (LOC105376244), rs7025144 (intergenic variant), and rs2022318 (intergenic variant). The results suggest that genetic background of comorbidity of asthma and hypertension is different from genetic backgrounds of both diseases manifesting isolated.
Adiponectin, leptin and high sensitivity C-reactive protein values in obese children – important markers for metabolic syndrome?
Authors: Stroescu Ramona F. , Mărginean Otilia , Bizerea Teofana , Gafencu Mihai , Voicu Adrian , Doroș Gabriela 
Published: December 2018

Abstract

Background
Obesity is a chronic inflammatory disorder in which leptin, adiponectin and C-reactive protein (CRP) play an important role. This study aimed to investigate the relationship between markers of adiposity such as leptin, adiponectin and high sensitivity C-reactive protein (hs-CRP) in obese children, and to determine whether these adipokines are significant markers in defining metabolic syndrome (MetS) in pediatric population.

Methods
A cross-sectional study was conducted over a period of 1 year, between July 2013 and June 2014, on 122 cases of obesity in children diagnosed at the Louis Ţurcanu Emergency Hospital for Children Timişoara, in the departments of Diabetes and Nutritional Diseases, Endocrinology and Cardiology. The patients were divided into two groups, according to the presence of MetS.

Results
MetS was present in 27% of obese children. The groups were homogenous with respect to age, sex and body mass index (BMI). Adiponectin, leptin and hs-CRP were significantly modified in the group with MetS (p=0.04, p=0.04, p=0.01, respectively).

Conclusions
hs-CRP, leptin and adiponectin can be used as predictors of cardiovascular risk in pediatric population.
Crystal structure of (1,2-dicarba-closo-dodecaborane-1,2-dithiolato κ2
S,S′)-bis(1,10-phenanthroline κ2
N,N′)zinc(II), C26H26B10Zn4S2
Authors: Liguo Yang , Xin Wang , Yongsheng Niu , Haixiang Song , Dayong Tian , Linna Gao 
Published: December 2018

Abstract
C26H26B10Zn4S2, monoclinic, P21/n, a = 14.3766(13) Å, b = 11.6360(11) Å, c = 18.9460(15) Å, β = 104.9630(10)°, V = 3061.9(5) Å3, Z = 4, R
gt(F) = 0.0451, wR
ref(F
2) = 0.0999, T = 298(2) K [1–3].
International teaching assistants’ identity as instructors and rapport with American students
Authors: Zhang Yuan 
Published: December 2018

Abstract
This study investigates whether international teaching assistants (ITAs), compared to American teaching assistants (ATAs), lack any rapport norms that may affect their teaching effectiveness and, if yes, what may cause their lack of those teaching rapport norms. Based on the rapport management theory from Spencer-Oatey (2000, 2008), teaching rapport in this study is delineated in terms of valued attributes as well as rights and obligations of both teachers and students. The data of this study consists of one-on-one interviews with 9 ITAs and 11 ATAs in regard to their self-perceived teaching rapport work and norms. The information from the ITA group was elicited in both the contexts of their country of origin and America and that from the ATA group was only in the American context. The comparison of self-perceived teaching rapport norms between the two groups shows that like ATAs, ITAs are familiar with the norms of teacher and student rights and obligations in American teaching. However, different from ATAs, ITAs do not value other teacher and student attributes beyond their perceived obligations for each role. The differences between ITAs’ self-perceived rapport work and norms in America and in their home country suggest that ITAs’ lack of these rapport norms may be caused by their resistance to the expected instructor identity and/or their mixed feelings about how invested they should be in the expected instructor identity. The findings have pedagogical implications for ITA training, second language acquisition, and English for specific purposes.
‘You dribble faster than Messi and jump higher than Jordan’: The art of complimenting and praising in political discourse
Authors: Kampf Zohar , Danziger Roni 
Published: December 2018

Abstract
Communicating admiration and appreciation in public discourse are two important tasks for political actors who wish to secure relationships and advance models for civic behavior. Our goal in this study is to understand how political actors signal their desire to please addressees and advance political sociability by way of manifesting positive judgment towards others. On the basis of 241 utterances praising and complimenting others’ words and deeds, we identify the topics, patterns, and functions of these speech acts and the processes and struggles they evoke in Israeli public discourse. We conclude by discussing the role of positive evaluations in demarcating the boundaries of proper conduct in political communities and the ways the distinctive logic of politics is integrated with specific cultural speaking styles in influencing how members of the Israeli political community signal their appreciation and affect for other members’ skills, performances, and personalities.
Why say it that way?: evasive answers and politeness theory
Authors: Marsh Jessica 
Published: December 2018

Abstract
Examples of evasive answers frequently appear in discussions of non-literal meaning comprehension. A considerable amount of work on this topic has focused on how this kind of non-literal meaning is generated. Of the researchers who have dealt with speakers’ motives for using evasive answers, and how hearers’ awareness of these motives affects their interpretations, the majority have focused on evasive answers that are not intended to be recognized as such&#x00A0;– in Gricean terms, those that violate the Maxim of Relation. Comparatively little research has dealt with answers that are blatant in their failure to answer the question&#x00A0;– that is, those that flout Relation.
This paper proposes that the majority of answers in the latter category can be understood using Brown and Levinson’s (1978, 1987) model of politeness&#x00A0;– in particular, that evasive answers are motivated by considerations for both speaker and hearer’s positive face-wants. Evasive answers are defined according to Roberts’ (2012) model of “the question under discussion” and characterized in terms of violating, infringing, or flouting Grice’s (1975) Maxim of Relation. Various contexts in which the latter category of evasive answers occur are identified and discussed with reference to their role in avoiding face-threatening acts. Potential exceptions to the proposition that blatantly evasive answers can be explained using Brown and Levinson’s (1978, 1987) model of politeness are identified, and problems with treating violating, infringing, and flouting as clearly distinct categories are discussed.
Evaluation of the effects of different treatment modalities on angiogenesis in heart failure patients with preserved ejection fraction via VEGF and sVEGFR-1
Authors: Erturk Ismail , Sertoglu Erdim , Bilgi Cumhur , Saglam Kenan , Yesildal Fatih , Acar Ramazan , Ozgurtas Taner 
Published: December 2018

Abstract

Objective
In this study, our aim was to investigate the clinical significance of VEGF, sVEGFR-1 in HFpEF patients.

Materials and methods
Seventy-two participants enrolled in this cross-sectional case-control study including HFpEF patients (n=41) and healthy (n=31) subjects. Blood samples were collected and serum VEGF, sVEGFR-1 analysis, and transthoracic echocardiography were performed.

Results and discussion
The average sVEGFR-1 level of HFpEF patient group was significantly higher than the control group (respectively 0.136 ng/L (0.04–0.34), 0.06 ng/L (0.01–0.25); p<0.001). The average VEGF level of HFpEF patients using beta blocker was significantly higher than the HFpEF patients not using it (respectively 0.585±0.194 ng/L; 0.349±0.269 ng/L; p=0.025). The average VEGF level of HFpEF patients using statins was significantly higher than the HFpEF patients without a medication (respectively 0.607±0.099 ng/L; 0.359±0.273 ng/L; p=0.038).

Conclusion
Our study is the first study demonstrating the relations among HFpEF, accompanying morbidities, VEGF and sVEGFR-1 levels. Statins and beta blockers may have positive effects on angiogenesis in HFrEF patients via increasing VEGF levels.
Analysis of early stroke-induced changes in circulating leukocyte counts using transcriptomic deconvolution
Authors: O’Connell Grant C. , Chang Julia H.C. 
Published: December 2018

AbstractGrowing evidence suggests that stroke alters the phenotype of the peripheral immune system; better characterization of this response could provide new insights into stroke pathophysiology. In this investigation, we employed a deconvolution approach to informatically infer the cellular composition of the circulating leukocyte pool at multiple timepoints following stroke onset based on whole blood mRNA expression. Microarray data generated from the peripheral blood of 23 cardiovascular disease controls and 23 ischemic stroke patients at 3, 5, and 24 hours post-symptom onset were obtained from a public repository. Transcriptomic deconvolution was used to estimate the relative counts of nine leukocyte populations based on the expression of cell-specific transcripts, and cell counts were compared between groups across timepoints. Inferred counts of lymphoid cell populations including B-cells, CD4+ T-cells, CD8+ T-cells, γδ T-cells, and NK-cells were significantly lower in stroke samples relative to control samples. With respect to myeloid cell populations, inferred counts of neutrophils and monocytes were significantly higher in stroke samples compared to control samples, however inferred counts of eosinophils and dendritic cells were significantly lower. These collective differences were most dramatic in samples collected at 5 and 24 hours post-symptom onset. Findings were subsequently confirmed in a second dataset generated from an independent population of 24 controls and 39 ischemic stroke patients. Collectively, these results offer a comprehensive picture of the early stroke-induced changes to the complexion of the circulating leukocyte pool, and provide some of the first evidence that stroke triggers an acute decrease in eosinophil counts.
Hypoglossal-facial ‘side’-to-side neurorrhaphy combined with electrical myostimulation for facial palsy in rats
Authors: Wang Binbin , Wang Shiwei , Liu Song , Zhang Shaodong , Li Dezhi , Li Junhua , Huang Xiongweiye , Schumacher Michael , Wan Hong 
Published: December 2018

Abstract
Introduction This study investigated the effect of combining hypoglossal-facial nerve “side”-to-side neurorrhaphy and electrical myostimulation in a rat model of facial palsy.
Methods Rats with facial nerve crush injury were subjected to control condition, monotherapy of either neurorrhaphy or electrical myostimulation, or bitherapy of the two treatments. After 1, 3, and 6 months, rats were performed the facial symmetry evaluation, electrophysiological examination and the retrograde labeling of motor neurons.
Results As early as 3 months after injury, face symmetry significantly improved in rats of the bitherapy group. At 3 or 6 months after injury, either the parameters of electrophysiological examination or the number of labeled motor neurons were significantly increased in the bitherapy group than in any other group.
Discussion The combination of neurorrhaphy and electrical myostimulation effectively promoted the functional recovery after facial nerve crush injury.
Density functional theory calculations of merohedric twinning in KLiSO4
Authors: Grimmer Hans , Delley Bernard 
Published: December 2018

Abstract
Density functional theory (DFT) calculations have been performed on five models of periodic, polysynthetic twin interfaces in the ambient-temperature phase of KLiSO4, which has space group P63. The models represent the three merohedric twin laws (m||z, 2⊥z and 1̅) with boundary plane (1 0 1̅ 0), also with boundary plane (0 0 0 1) in case of m, and with boundary plane (1 2̅ 1 0) in case of 1̅. The models satisfy stoichiometry at the boundary plane and maintain the fourfold coordination of the Li and S atoms and the twofold coordination of the oxygen atoms. Relaxed lattice parameters and atomic positions were determined by DFT, using the DMol3 code with functional PBEsol. The energy difference between polysynthetic twin and single crystal per primitive cell of the twin is 0.0009 eV for m(0 0 0 1), 0.09 eV for 1̅(1 0 1̅ 0), 0.58 eV for m(1 0 1̅ 0) and 0.55 eV for 2(1 0 1̅ 0). In KLiSO4 crystals grown from aqueous solutions the first twin was frequently observed, similarly also the second twin in Cr-doped crystals, whereas the third twin appeared only rarely and the fourth was not observed. Not only for KLiSO4 but also for quartz, the energy of twins and the frequency of their occurrence are closely connected for crystals grown from aqueous solutions, whereas for the formation of transformation twins the availability of twin nuclei plays a major role.
Analysis of the GC-MS of volatile compounds and the phytochemical profile and antioxidant activities of some Bulgarian medicinal plants
Authors: Mihaylova Dasha , Vrancheva Radka , Desseva Ivelina , Ivanov Ivan , Dincheva Ivayla , Popova Mariya , Popova Aneta 
Published: December 2018

Abstract
The study’s objective was to investigate the volatile compounds, assess the total phenolic content and phenolic acids profile, determine the antioxidant capacity and evaluate the anthocyanin and flavonoid contents in stinging nettle (Urtica dioica L.), tansy (Tanacetum vulgare L.), bladder campion (Silene vulgaris (Moench) Garcke) and rosehip fruit (Rosa canina L. cv. Plovdiv 1). The total phenolic content ranged from 0.55±0.00 to 47.39±0.41 mg GAE/g dw, total flavonoids ranged from 0.45±0.02 to 17.27±0.45 mg QЕ/g dw and the total anthocyanins ranged from 0.94±0.23 to 58.11±2.85 mg/L. The results demonstrated that the selected research plants show auspiciously useful properties in fields like pharmacy, food preparation, cosmetics, etc. Furthermore, the most promising extraction methods in terms of bioactivity are decoction and tincture (U. dioica; T. vulgare; S. vulgaris) and tincture (R. canina). The current study could be regarded as a first detailed investigation of the biological activity and phytochemical composition of R. canina L. cv. Plovdiv 1.
Topological characterization of dendrimer, benzenoid, and nanocone
Authors: Gao Wei , Siddiqui Muhammad Kamran , Rehman Najma Abdul , Muhammad Mehwish Hussain 
Published: December 2018

Abstract
Dendrimers are large and complex molecules with very well defined chemical structures. More importantly, dendrimers are highly branched organic macromolecules with successive layers or generations of branch units surrounding a central core. Topological indices are numbers associated with molecular graphs for the purpose of allowing quantitative structure-activity relationships. These topological indices correlate certain physico-chemical properties such as the boiling point, stability, strain energy, and others, of chemical compounds. In this article, we determine hyper-Zagreb index, first multiple Zagreb index, second multiple Zagreb index, and Zagreb polynomials for hetrofunctional dendrimers, triangular benzenoids, and nanocones.
Learn to Learn: Application to Topology Optimization
Authors: Wei Qi , Akrotirianakis Ioannis , Dasgupta Arindam , Chakraborty Amit 
Published: December 2018

Abstract
The objective of this article is to propose a new algorithm for topology optimization (TO), specifically in the context of additive manufacturing (AM). TO as a part design mechanism is particularly synergestic with AM. We propose to solve the TO problem using a pretrained deep neural network (DNN). We develop a variation of DNN architecture that has been used successfully in image processing, and its adaptation to TO problems constitutes the main focus of our work. We use a deep convolutional neural network to learn end-to-end mapping from the initial designs obtained by running solid isotropic material with penalization (SIMP) for a few iterations to the final optimal designs obtained when SIMP runs to convergence. The iterative updates from the initial designs to the converged ones is replaced by forward propagation through the trained DNN. Our approach can be thought of as a way to the develop a trained DNN that can imitate the gradient descent method used in the standard SIMP method. We present computational results that demonstrate that our approach can compete favorably with SIMP.
Clinical, microbiological research of the effectiveness of inhalation use of quaternary ammonium antiseptic in the prevention and treatment of infectious respiratory complications in critically ill patients
Authors: Nazarchuk Oleksandr A. , Dmytriiev Dmytro V. , Dmytriiev Kostiantyn D. 
Published: December 2018

Introduction: The aim is to study the microbiological and clinical efficacy of decamethoxinebased quaternary ammonium antiseptic inhalations in the complex management of respiratory infectious complications in critically ill children.
Methods: The use of inhalation of antiseptic medicinal decamethoxine (DCM) was studied in patients with ventilator-associated pneumonia (VAP) (n=30), of ages 12-18 years. All patients received standard intensive care according to the guidelines. Inhalations of 5 mL DCM (0.02%) antiseptic per inhalation TID for 7 days in combination with systemic antibiotic therapy were used in the study group (n=15). Clinical microbiological studies and assessment of Toll-like receptor (e.g. TLR-4) serum levels were performed in patients.
Results: The use of DCM inhalations along with systemic antibiotic therapy improved parameters of dynamic compliance by 3.4-fold and decreased lung resistance by 2.4-fold in patients after 48-72 hours of mechanical ventilation. The microbial spectrum of patients at the beginning of VAP was represented by gram-positive (S. aureus — 28.6%, S. pyogenes — 10.2%) and gramnegative (P. aeruginosa — 16.3%; A. baumannii — 12.24%; K. pneumoniae — 10.2%) pathogens. The pathogens were isolated in the monoculture (20.4%) and in microbial associations (79.6%). A significant decrease by 3 orders of magnitude (log (2.640.43) CFU/mL) in the microbial count in tracheobronchial secretions was determined after 7 days of additional use of DCM inhalations when compared to the initial levels of microbial colonization (p<0.001). The microbial spectrum of the respiratory tract was predominantly represented by S. aureus (27.78%), A. baumannii (11.11%) and E. cloacae (5.56%) in monoculture (61.11%), whereas the microbial count was 4 orders of magnitude higher in the comparison group, versus that of the study group (p<0.001), and was represented by microbial associations (93.33%). A strong correlation was found between the reduction of the gram-negative pathogen count and the decrease of TLR-4 serum levels (r-Pearson=0.893), that almost reached baseline levels after DCM inhalations, while TLR-4 levels remained 2 times higher than baseline levels after the use of systemic antimicrobial therapy alone (p<0.001).
Conclusion: The use of DCM inhalations in combination with systemic antibiotic therapy provides for an effective reduction of pathogen count in the respiratory tract, leading to the early (48-72h) improvement in lung ventilation and TLR-4 serum levels, and subsequent significant improvement of treatment efficacy in severe VAP patients.