bluuebunny/crossref_metadata_2025_split huggingface dataset:
MICROSPORE ANALYSIS FOR GENOTOXICITY OF POLLUTED ATMOSPHERIC ENVIRONMENT (THE CASE STUDY IN THE MATARAM CITY)
Authors: Suripto Suripto , Sukenti Kurniasih , Sukiman Sukiman , Rohyani Immy Suci , Jupri Ahmad 
Published: August 2019

Abstract : The need for environmental protection continues to increase, so exploratory studies of agents of polluted environmental indicators are becoming increasingly important. The advantages of using flowering plants for environmental bio-indicator studies include the availability of sufficient test material with their variations and the availability of different periods for sampling. Seven plant species were used to examine their suitability as bio-indicator for genotoxicity of polluted atmospheric environment in Mataram City by microspore analysis. This study was conducted with the aim of, 1) knowing the level of difference in the frequency of failure (abortiveness) of microspores between similar plants that grow in areas at risk of being polluted in the city and those growing in areas not at risk of being polluted outside the city of Mataram, and 2) find out what types of flowering plants, especially those in city parks that are suitable as bio-indicators of air pollution for Mataram City. The percentage of aborted pollens was calculated out of 50 to 300 observed pollen grains of each selected individual flowering plant. Sample of each plant species from every study area consist of ten plant individuals. Data were analyzed by use the Wilcoxon one way-test at a 0.05 to determine significance of difference in the percentage of aborted pollen grains from same plant species between in the risky polluted area and plant in the control area.ÃÂ The results showed that Lantana camara L. is suitable as bio-indicator for atmospheric pollution in Mataram City or other cities that have a density of traffic flow of motorized vehicles around 100 vehicles per hour. Its percentage of aborted pollen grains is 1,62 ÃÂ±ÃÂ 0,08 % in the risky polluted area,ÃÂ andÃÂ ÃÂ 1,21 ÃÂ± 0,13 % in the control area. Others six observed plant spesies, i.e.ÃÂ Acacia auriculiformis A. Conn. Ex Bth., Bauhinia acuminata L., Baugenvillea spectabilis Willd. Duranta erecta L., Ixora coccinea L. and Rosa hybryda Hort., each of them is not suitable as bioindicator for it. Their percentage of pollen abortiveness in polluted and not-polluted areas were not different, significantly.Keywords: Genotoxicity, Microspores, Polluted air environment
A grading scale for surgically treated patients with spontaneous supratentorial intracerebral hemorrhage: the Surgical Swedish ICH Score
Authors: Fahlström Andreas , Nittby Redebrandt Henrietta , Zeberg Hugo , Bartek Jiri , Bartley Andreas , Tobieson Lovisa , Erkki Maria , Hessington Amel , Troberg Ebba , Mirza Sadia , Tsitsopoulos Parmenion P. , Marklund Niklas 
Published: August 2019

OBJECTIVEThe authors aimed to develop the first clinical grading scale for patients with surgically treated spontaneous supratentorial intracerebral hemorrhage (ICH).METHODSA nationwide multicenter study including 401 ICH patients surgically treated by craniotomy and evacuation of a spontaneous supratentorial ICH was conducted between January 1, 2011, and December 31, 2015. All neurosurgical centers in Sweden were included. All medical records and neuroimaging studies were retrospectively reviewed. Independent predictors of 30-day mortality were identified by logistic regression. A risk stratification scale (the Surgical Swedish ICH [SwICH] Score) was developed using weighting of independent predictors based on strength of association.RESULTSFactors independently associated with 30-day mortality were Glasgow Coma Scale (GCS) score (p = 0.00015), ICH volume ≥ 50 mL (p = 0.031), patient age ≥ 75 years (p = 0.0056), prior myocardial infarction (MI) (p = 0.00081), and type 2 diabetes (p = 0.0093). The Surgical SwICH Score was the sum of individual points assigned as follows: GCS score 15–13 (0 points), 12–5 (1 point), 4–3 (2 points); age ≥ 75 years (1 point); ICH volume ≥ 50 mL (1 point); type 2 diabetes (1 point); prior MI (1 point). Each increase in the Surgical SwICH Score was associated with a progressively increased 30-day mortality (p = 0.0002). No patient with a Surgical SwICH Score of 0 died, whereas the 30-day mortality rates for patients with Surgical SwICH Scores of 1, 2, 3, and 4 were 5%, 12%, 31%, and 58%, respectively.CONCLUSIONSThe Surgical SwICH Score is a predictor of 30-day mortality in patients treated surgically for spontaneous supratentorial ICH. External validation is needed to assess the predictive value as well as the generalizability of the Surgical SwICH Score.
THE CHANGES OF HUMORAL ADRENERGIC REGULATION OF HEART IN ALCOHOL-TREATED RATS
Authors: Panova T.I. , Koshelnyk M.I. , Scherbak S.N. 
Published: August 2019

Relevance. Under the chronic influence of ethanol the genes expression is changed which contain the information about synthesis of adrenergic receptors, epinephrine enzymes. However studies of the systemic manifestations of these changes are unknown. The distortion of the adrenergic drugs effect in an alcohol-treated organism is probable.
Objective: to investigate the adrenergic regulation of the heart in alcohol-treated rates by means of variation of the number of β1 receptors and their ligands.
Materials and methods. In control (n=10) and alcohol-treated rats chronically for 120 days (n=10) the number of β1-adrenergic receptors (by means of administration of concor cor selective blocker – 0,28 mg/kg) and the quantity of epinephrine in the blood (by means of activation of sympathoadrenal system after sodium caffeine-benzoate injection – 7,14 mg/kg) were varied. The concor cor and caffeine were administered separately and together. The heart rate (HR) was recorded with the help of sphygmomanometer. The results were processed by using MedStat package.
Results. In alcohol-treated rats chronically the HR is 27,6±2,5% higher than in the control ones (383,8±12,9 min-1 and 300,8±8,7 min-1). The caffeine administration leads to an increase in heart rate by 11,5±1,1 % in control rats (up to 335,4±9,5 min-1) while it doesn’t affect this index in alcohol-treated rats (389,6±12,6 min-1). The blockade of β1 receptors leads to a decrease in the HR by 7,5±0,7 % (up to 278,2±7,9 min-1) in control rats and by 15,5±1,1 % (up to 324,4±9,3 min-1) in alcohol-treated rats. When co-administration the β1 receptors blocker and caffeine have nivelated the opposite effects of each other in the control rats and HR remained the same (307,0±8,2 min-1); this has resulted in a decrease in the HR by 4,8±1,0 % (up to 365,4±10,9 min-1) in alcohol-treated animals.
Conclusions. It is assumed that the basal secretion of epinephrine is increased and the number of β1 receptors is decreased in alcohol-treated rats compared to control ones.
EFFICIENCY OF INHALATION AND PARENTAL THERAPY OF ACUTE BRONCHIAL OBSTRUCTION SYNDROME BY INFECTIOUS OR ALLERGIC GENESIS IN CHILDREN. PRINCIPLES AND TECHNIQUE OF INHALATIONS
Authors: Strizh V.A. 
Published: August 2019

Relevance. Diseases of the respiratory organs occupy the first ranked place in the structure of the incidence of children, reaching 50-75 % in the regions of Ukraine. The prevalence of the syndrome of bronchial hyperactivity increases . Objective: to study the effectiveness of nebulizer therapy for relief of acute bronchial obstruction syndrome in children with exacerbation of recurrent bronchitis or bronchial asthma. Materials and methods. 52 children of school age with acute bronchial hyperactivity (recurrent bronchitis – 28, bronchial asthma – 24) were examined. Two groups were formed by randomization: the main group (27 children) and the control group (25 children). Both groups were representative by sex, age, nosological diagnosis and severity of the disease. All children received basic therapy with topical glucocorticosteroids by nebulization. Children of the main group received intensive treatment by salbutamol inhalation during the first treatment day, and on 2–5 days as in the control group only 3 times a day. Children of the control group received inhalations together with intravenous drip infusions of euphyllin and dexamethasone. Results. In both groups, there was a dynamic regression of cough and sputum excretion, but in the main group, the rate of disappearance of cough by the 5th day of treatment was 3 times, and by the 10th day – 2,3 times higher, than in the control (p < 0.05); the rate of disappearance of sputum within 10 days is 1,7 times higher, respectively (p <0.05). Positive changes were confirmed by an auscultative pattern, the normalization of which occurred earlier for 1 week in patients receiving intensive nebulization bronchodilator therapy during the first day of the treatment. Conclusions. Competent use of nebulizers allows to increase the effectiveness of treatment of children with acute bronchial obstructive syndrome. Early relief of bronchospasm promotes faster normalization of inspiratory flow and respiration recovery. As a result, the terms of recovery and length of stay of children in the hospital are shortened.
INFLUENCE OF ARTERIAL HYPERTENSION WITH DIFFERENT DURATION ON NEUROLOGICAL AND FUNCTIONAL OUTCOME OF ISCHEMIC STROKE
Authors: Cheren’ko T.M. , Heletyuk Yu.L. 
Published: August 2019

Relevance. The outcome of acute ischemic stroke depends on the complex interaction of many factors, such as those that are not controllable, and those that can be affected. An important prognostic value of blood pressure level during the first day after a stroke has been proven. At the same time, the relationship between the primary ischemic stroke outcome and various characteristics of arterial hypertension (duration, severity of pre-existing arterial hypertension, its course) continues to be studied.
Objective: to study the relationship between the degree of neurological recovery and functional dependence in patients after ischemic stroke within 1 year, depending on the duration of arterial hypertension in the pre-stroke period.
Materials and methods. The study included 156 patients, 6 patients were excluded because of the loss of communication with them and refusal to participate in the study. 150 patients, 74 (49,3 %) women and 76 (50,7 %) men aged 43 to 80 years (mean age 67.4±0,71 years) with a history of ischemic stroke and the presence of arterial hypertension were examined during the year, on 1, 21 days, after 6 and 12 months. The stroke severity was evaluated by NIHSS, functional dependence – by the Barthel Index. The diagnosis of arterial hypertension, its severity, duration was based on data from clinical, instrumental examination and medical documentation.
Results. The severity of ischemic stroke by NIHSS at the time of admission was 9,5±0,35 points; the average degree of neurological disorders severity was determined in 57,4 % of patients. The arterial hypertension duration in the history of examined patients varied from 2 to 45 years, the average 12,3±0,64 years. The most commonly reported was the arterial hypertension with its duration 6-10 years (46 %). In the case of arterial hypertension duration up to 5 years, the ischemic stroke has developed in 18,7 % of patients. The duration of arterial hypertension in anamnesis significantly correlated with the severity of the neurological deficiency at the time of admission and at the end of the acute period (r=0,65; r=0,66, respectively). The degree of functional dependence in patients with arterial hypertension duration over 10 years was worse comparatively with patients that had arterial hypertension duration up to 5 years and even with patients with a duration from 6 to 10 years after 6 and 12 months period (61,7±2,1; 90,9±1.1; 82,8±1,4 and 64,9±2,7; 93,2±0,9; 85,7±1,3, correspondingly, all p <0,05).
Conclusions. The reliable direct relationship between the arterial hypertension duration and the degree of neurological disorders in the acute period of ischemic stroke and the reverse relationship between the duration of arterial hypertension and the degree of functional recovery in all periods of the study were found. The most patients with moderate and severe functional dependence in a year have arterial hypertension duration more than 10 years.
HYGIENIC EVALUATION OF A NEW ACTIVE INGREDIENT CYCLOXIDIM BEHAVIOR IN THE ENVIRONMENTAL OBJECTS
Authors: Hulai T.O. , Omelchuk S.T. , Antonenko A.M. 
Published: August 2019

Relevance. Sunflower plants are very demanding for the soil and require optimal moisture, especially for the development phase of 2-3 pairs of leaves. It is important to use herbicides at this stage of vegetation as weeds can lead to impoverishment of soil and nutrients, and contribute to the development of pests and diseases.
Objective of the work is the hygienic assessment of the behavior of the new herbicide Stratos Ultra in the objects of the environment and the justification of the hygienic norms of its active substance cycloxydim in sunflower seeds and soils.
Materials and methods. Natural research was conducted on the basis of the «Kremenne» farm in the Kyiv region, Brovarsky district, p. Gogoliv. The stability of cycloxydim in soils and plants was estimated according to the calculated half-life (τ50) and almost complete destruction (τ95) of the substance periods. Mathematical processing of the results obtained in the program Microsoft Excel.
Results. After treatment initial concentrations of the cycloxydim in the soil and green mass of plants were 0,43±0,07 mg/kg and 0,5±0,04 mg/kg, respectively. At the same time, in the soil-climatic conditions of Ukraine, τ50 in the field conditions is on average 8 days (7,57-8,90 days), τ95 – 35 days (35,37-38,97 days), in other European countries cycloxydim τ50 is on average 5 days (1-10 days), and τ50 of the main metabolite – cycloxydim-sulfoxide (ВН 517-ТСО) – 16 days. MAC in water of water reservoirs – 0,06 mg/dm3.
Conclusions. Cycloxydim can be attributed to the IV class (low hazardous), for resistance to water – to the first class of danger. Approximately acceptable concentration in the soil is grounded at the level of 0,3 mg/kg. Based on the results of the determination of the actual content of cyclooxydim in sunflower seeds, The maximum acceptable level in sunflower seeds is 0,4 mg/kg, and for sunflower oil is not substantiated.
TREATMENT OF FULMINANT VIRAL HEPATITIS B WITH ACUTE HEPATIC ENCEPHALOPATHY WITH INTRAVENOUS IMMUNOGLOBULIN: PRESENTATION OF A CLINICAL CASE
Authors: Maltsev D.V. , Muzyca D.P. 
Published: August 2019

At hepatology intravenous immunoglobulin was tested in several areas, but the evidence base of effectiveness is different at each nosology and often insufficient for routine use of the drug. However, immunoglobulin therapy may be useful for hepatologist in the management of severe, unusual clinical cases in the framework of a personalized treatment, in connection with which specialist should be well informed about the current experience of using immunotherapy for various hepatological indications.
This article describes clinical case of fulminant viral hepatitis B with acute liver failure and encephalopathy in which managed to save the life of the patient only after the addition to the standard treatment regimen intravenous immunoglobulin.
THE ROLE OF MAGNESIUM DEFICIENCY AND ITS SUPPLEMATION IN DISEASES OF CENTRAL NERVOUS SYSTEM. REVIEW
Authors: Khaitovych M.V. 
Published: August 2019

Relevance. Anti-depressant effects of NMDA receptor antagonists have been proven, a close association between low levels of magnesium in the blood and depression. Therefore, in recent years, antidepressant properties of magnesium are actively studied in animal experiments. Objective: To review modern literary sources about the role of magnesium deficiency in the pathogenesis of diseases of the central nervous system. Materials and methods. Searching for a depth of 12 years at Scopus, Google Scholar. Results. The results of experimental and clinical researches pointed out on association between low level of magnesium in hair, liquor, brain with higher risk of development dementia, depression and anxiety. An additional supplementation with magnesium in patients associates with decreasing risk of ischemic stroke and dementia, in pregnancy – provides neuroprotection of fetus, in case of depression increases effectiveness of antidepressants, in brain injury associates with faster recovery of cognitive functions, in migraines - with decreasing in the frequency of attacks and improvement of the quality patients’ lives, in case of neuroleptic therapy - with the possibility of delayed appearance or absence of manifestations of drug parkinsonism. These changes are explained by antagonistic effects of magnesium on glutamate receptors, decreasing oxidative stress intensity as well as neural cell apoptosis. Conclusion. Magnesium plays an important neuroprotective role.
THERANOSTICS – A UNIQUE CONCEPT OF NUCLEAR MEDICINE. REVIEW
Authors: Korol Р. , Tkachenko М. 
Published: August 2019

Relevance. Theranostics – a new approach to the development of pharmaceutical compositions is the ability to comprehensively solve therapeutic and diagnostic problems by searching for drugs that are both a means of early diagnosis, and a therapist agent.
Objective. Determine, according to the literature, the basic conceptual principles of theranostics, as a modern therapeutic and diagnostic direction in nuclear medicine.
Material and methods. The implementation of the main conceptual issues of theranostics was solved by applying modern methods of diagnostic imaging in nuclear medicine, including, first of all, the use of PET and SPECT using positron and gamma-emitting radionuclide.
Results. In order to improve and develop the concept of theranostics, it is promising to use the strengths of nuclear medicine, by developing platforms for identifying new biological substrates, predicting possible negative consequences and providing practical tools aimed at determining objective and quantitative criteria for monitoring the evaluation of the quality of therapeutic procedures. Preparations of most chemical or even inorganic compositions specifically designed for particular cellular or biochemical targets can be modified into a complex of images by appropriate conjugation with images obtained from modern synthesized radionuclide.
Conclusions. Theranostics as a unique concept of nuclear medicine can be actively used in the practical and scientific work of the radionuclide diagnostics and nuclear medicine, oncology, urology and other departments. The proposed concept is also useful for monitoring changes in a malignant tumor in dynamics, while monitoring the quality of treatment for cancer patients.
Shaykh Yusuf of Macassar; Scholar, Sufi, National Hero: Towards Constructing Local Identity and History at the Cape
Authors: Cassiem Armien 
Published: August 2019

This paper focuses on the Origins and Malaya presence of Islam in both ritual practices and daily life of modern day Islam as practiced by Muslims in Cape Town, South Africa. It also tries to capture the presence of Shaykh Yusuf s short time spent at the Cape, 1694 - 1699, and how this period of his life gives expression to local history, storytelling, tradition and meaning to Islam in contemporary Cape Town.
Keywords: Shaykh Yusuf, Macassar, South Africa, Ritual Practices, Local Identity
Seeking for Berkah: the Celebration of Kiai Slamet
Authors: Imamah Fardan Mahmudatul 
Published: August 2019

Abstract One of many annual traditional Javanese ceremony for celebrating the new year is Kirab Kiai Slamet. This ceremony was held in Surakarta, Central Java by one of greatest Javanese Kingdom, Keraton Surakarta Hadiningrat. A thousand visitors who have come from all over of java just to see this ceremony bring various motives. This paper will elaborate how the perspective of Javanese people interprets their attendance on Kirab Kiai Slamet? One of their motives is berkah, then how they perceive this concept of ‘ngalap berkah’? While berkah is one of the most prevalent religious practices in Indonesia, there are various meaning on it from a diverse group. In an effort to reveal the various interpretation of the concept of ‘berkah’, this paper offers an alternative perspective of the study of religion. Because the study of religion is more dominated by world religion paradigm that rigidly defines ‘religion’ as the structured form of religious tradition, an alternative perspective will be needed. After elaborating the experiment of Kirab Kiai Slamet and framed by some theories of religions, this paper will show how ‘indigenous religion paradigm’ have a positive contribution to the enriching of theories of religions in contemporary issues. Keywords: berkah (blessing), Kiai Slamet, world religion paradigm, indigenous worldview.
Local Politics and the Formation of Sub-National Imagined Communities: The Cases of Tabanan Lovers and Buleleng Jengah in Bali
Authors: Mentere GdeDwitya Arief 
Published: August 2019

Abstract
This essay looks at two cases of cyber citizen organizations namely Tabanan Lovers and Buleleng jengah. The two cyber citizen organizations emerged from some initiatives to organize members of Facebook community who come from the same hometown, namely Tabanan and Buleleng regency in Bali. In their later development, the two Facebook groups evolve into a space as well as a medium for the cyber citizens to voice their critical political aspiration. Early observation shows that the two groups share similar characteristic of becoming “imagined communities” mediated by not necessarily print media, but instead social media like Facebook. A question that this essay would like to suggest as a future research agenda is what necessitates the formation of these “subnational imagined communities” which takes place at the regency level and not at provincial level? Through tracing the history of their conception and through online participatory observation, this essay aims at providing a preliminary discussion to help illuminate the formation of these two subnational “imagined communities”. More specifically, the discussion points to a link connecting local politics of pilkada and the formation of Tabanan Lovers and Buleleng jengah.
Magic and the Communist Revolt of 1926 in Banten: a Study on the Script of K.H. Muqri Labuan
Authors: Ulumi Helmy Faizi Bahrul 
Published: August 2019

Abstract
Studies on magic in civil revolts in Indonesia are remarkably scarce. The use of magic in Bantenese revolts are presented in the works of Kartodirdjo (1966) and Williams (1982,1990). This article explains several aspects of magic such as the form, the ritual, and thesources related to magic sourced from the Script of K.H. Muqri Labuan, one of the important figures in the communist revolt of 1926 in Banten, by using philological and historical approaches. The Script was written byK.H. Muqri during his escapee from Surabaya to Mecca when the Dutch colonial could defeat his rebellion in Labuan. His script is 17,5x21 cm consisted of 540pages written in Jawiand Arabic. It mostly contains the magical formula and wird of severaltariqa. It also comprises his genealogy, the magical licence (ijâzah)he obtained, his journey notes to Mecca, his activities during living in Mecca, and the list of his disciples.