bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temperature but not the circadian clock determines nocturnal carbohydrate availability for growth in cereals
Authors: Müller Lukas M. , Gol Leonard , Jeon Jong-Seong , Weber Andreas P.M. , Davis Seth J. , von Korff Maria 
Published: July 2018

AbstractThe circadian clock is considered a key target for crop improvement because it controls metabolism and growth in Arabidopsis. Here, we show that the clock gene EARLY FLOWERING 3 (ELF3) controls vegetative growth in Arabidopsis but not in the cereal crop barley. Growth in Arabidopsis is determined by the degradation of leaf starch reserves at night, which is controlled by ELF3. The vegetative growth of barley, however, is determined by the depletion of leaf sucrose stores through an exponential kinetics, presumably catalyzed by the vacuolar sucrose exporter SUCROSE TRANSPORTER 2 (SUT2). This process depends on the sucrose content and the nighttime temperature but not on ELF3. The regulation of starch degradation and sucrose depletion in barley ensures efficient growth at favorable temperature as stores become exhausted at dawn. On cool nights, however, only the starch degradation rate is compensated against low nighttime temperatures, whereas the sucrose depletion rate is reduced. This coincides with reduced biomass in barley but not in Arabidopsis after growth in consecutive cool nights. The sucrose depletion metabolism determines growth in the cereal crops barley, wheat, and rice but is not generally conserved in monocot species and is not a domestication-related trait. Therefore, the control of growth by endogenous (clock) versus external factors (temperature) is species-specific and depends on the predominant carbohydrate store. Our results give new insights into the physiology of growth in cereals and provide a basis for studying the genetics and evolution of different carbohydrate stores and their contribution to plant productivity and adaptation.Significance StatementThe circadian clock controls growth in the model plant Arabidopsis thaliana by regulating the starch degradation rate so that reserves last until dawn. This prevents nocturnal starvation until photosynthesis resumes. The cereal crops barley, wheat and rice, however, predominantly consume sucrose instead of starch as carbohydrate source. We find that carbohydrate supply from sucrose at night is regulated by enzyme kinetics and night-time temperature, but not the circadian clock. We postulate that the regulation of growth depends on the predominant carbohydrate store, where starch degradation is controlled by endogenous cues (clock) and sucrose depletion by external factors (temperature). These differences in the regulation of carbohydrate availability at night may have important implications for adapting crops yields to climate change.
Limits on visual awareness of object targets in the context of other object category masks: Investigating bottlenecks in the continuous flash suppression paradigm with hand and tool stimuli
Authors: Zopf Regine , Schweinberger Stefan R. , Rich Anina N. 
Published: July 2018

AbstractOur capacity to become aware of visual stimuli is limited. Investigating these limits, Cohen et al. (2015, Journal of Cognitive Neuroscience) found that certain object categories (e.g., faces) were more effective in blocking awareness of other categories (e.g., buildings) than other combinations (e.g., cars/chairs) in the continuous flash suppression (CFS) task. They also found that more category-pair representational similarity in higher visual cortex was related to longer category-pair breakthrough times suggesting a high-level representational architecture bottleneck for visual awareness. As the cortical representations of hands and tools overlap, these categories are ideal to test this further. We conducted CFS experiments and predicted longer breakthrough times for hands/tools compared to other pairs. In contrast to these predictions, participants were generally faster at detecting targets masked by hands or tools compared to other mask categories when giving manual (Experiment 1) or vocal responses (Experiment 2). Furthermore, we found the same inefficient mask effect for hands in the context of the categories used by Cohen et al. (2015) and found a similar behavioural pattern as the original paper (Experiment 3). Exploring potential low-level explanations, we found that the category average for edges (e.g. hands have less detail compared to cars) was the best predictor for the data. However, these category-specific image characteristics could not completely account for the Cohen et al. (2015) category pattern or for the hand/tool effects. Thus, several low- and high-level object category-specific limits for visual awareness are plausible and more investigations are needed to further tease these apart.
Investigations of the mechanisms of interactions between four non-conventional species withSaccharomyces cerevisiaein oenological conditions
Authors: Harlé Oliver , Legrand Judith , Tesnière Catherine , Pradal Martine , Mouret Jean-Roch , Nidelet Thibault 
Published: July 2018

AbstractFermentation by microorganisms is a key step in the production of traditional food products such as bread, cheese, beer and wine. In these fermentative ecosystems, microorganisms interact in various ways, namely competition, predation, commensalism and mutualism. Traditional wine fermentation is a complex microbial process performed bySaccharomycesand non-Saccharomyces(NS) yeast species. To better understand the different interactions occurring within wine fermentation, isolated yeast cultures were compared with mixed co-cultures of one reference strain ofS. cerevisiaewith one strain of four NS yeast species (Metschnikowia pulcherrima, M. fructicola, Hanseniaspora opuntiae and H. uvarum). In each case, we studied population dynamics, resource consumed and metabolites produced from central carbon metabolism. This phenotyping of competition kinetics allowed us to confirm the main mechanisms of interaction between strains of four NS species.S. cerevisiaecompeted withH. uvarumandH. opuntiaefor resources although bothHanseniasporaspecies were characterized by a strong mortality either in isolated or mixed fermentations.M. pulcherrimaandM. fructicoladisplayed a negative interaction with theS. cerevisiaestrain tested, with a decrease in viability in co-culture, probably due to iron depletion via the production of pulcherriminic acid. Overall, this work highlights the importance of measuring specific cell populations in mixed cultures and their metabolite kinetics to understand yeast-yeast interactions. These results are a first step towards ecological engineering and the rational design of optimal multi-species starter consortia using modeling tools. In particular the originality of this paper is for the first times to highlight the joint-effect of different species population dynamics on glycerol production and also to discuss on the putative role of lipid uptake on the limitation of some non-conventional species growth although interaction processes.
Molecular Complexes for Effective Inhibition of Tau Aggregation
Authors: Gorantla Nalini V. , Landge Vinod G. , Nagaraju Pramod G. , Sunny Lisni P. , Nair Anjhu , Midya Siba P. , Priyadarshini CG Poornima , Balaraman Ekambaram , Chinnathambi Subashchandrabose 
Published: July 2018

ABSTRACTTau is an axonal protein known to form abnormal aggregates and is the biomarker of Alzheimer’s disease. Metal-based therapeutics for inhibition of Tau aggregation is limited and rarely reported in the contemporary science. Here, the first example is reported of a rationally designed molecular cobalt(II)-complexes for effective inhibition of Tau and disaggregation of preformed Tau fibrils. The mechanistic studies revealed that the prevention of Tau aggregation by CBMCs is concentration-dependent and Tau seldom exhibits conformational changes. Interestingly, CBMCs play a dual role by causing disassembly of preformed aggregates as well as complete Tau inhibition. We believe that this unprecedented finding by the newly developed molecular complexes has a potential to lead to developing innovative metal-based therapeutics for Alzheimer’s disease.
Digitalization of aircraft performance nomograms
Authors: Mirosavljević Petar D. , Pantović Đorđe I. , Mijailović Radomir M. 
Published: July 2018

Purpose
The purpose of this paper is to develop a new tool for aircraft performance analysis and optimization.

Design/methodology/approach
In this paper, the methodology of converting nomogram curves into mathematical functions is presented. Aircraft performance nomograms represent graphical interpretation of influence of several variables on performance such as environmental conditions, runway conditions and aircraft mass. The aircraft performance nomograms are converted in mathematical functions that describe several independent variables’ influence on aircraft performance parameters. To achieve greater accuracy in calculation of aircraft performance parameters, it is necessary to determine mathematical functions presented by dependent variable variations with several independent variables. The method of determining mathematical functions is illustrated on Fokker 100 landing gear extended net climb gradient determination graph.

Findings
To evaluate model, it was necessary to determine net climb gradient both graphically and analytically using model and compare the results. After solving both analytically and graphically, it was concluded that results are a match. During model evaluation, it was observed that model has a lot of advantages such as it has great precision of calculation, requires less time to calculate results and has minimum error possibility.

Practical implications
Final result of digitalization of aircraft performance nomograms is software production. The usage of this software can reduce flight planning and aircraft exploitation costs in several different manners. Airliners can produce such a software for those types of aircraft where there is no software provided from aircraft manufacturer.

Originality/value
Digitalization of aircraft performance nomogram has never been analyzed before, although there is a possibility of this particular methodology implementation in a practical manner in aviation industry.
Do return to work interventions for workers with disabilities and health conditions achieve employment outcomes and are they cost effective? A systematic narrative review
Authors: Dibben Pauline , Wood Geoffrey , O’Hara Rachel 
Published: July 2018

PurposeThe purpose of this paper is to evaluate existing evidence on whether return to work interventions achieve employment outcomes and are cost effective in order to better inform those needing accommodations at work, as well as their line managers and trade union representatives, occupational health specialists and HR managers.Design/methodology/approachThe paper uses a systematic narrative review to evaluate the evidence on the employment outcomes and cost effectiveness of return to work initiatives.FindingsEvidence on interventions for musculoskeletal conditions such as lower back pain indicates that certain forms of intervention such as vocational rehabilitation and workplace-based rehabilitation facilitate outcomes such as employment, reduced sick leave and effective return to work. However, there is very little evidence on whether these interventions are cost effective. More generally there are glaring gaps in evidence on cardio-respiratory (heart and breathing) and mental health conditions with regard to both employment outcomes and the cost of interventions.Research limitations/implicationsThis systematic review has critical and timely implications for both knowledge development and practice. While highlighting methodological limitations in the existing research base, it also presents avenues for further research on return work strategies and the factors inhibiting and facilitating their adoption and effective operation.Originality/valueAlthough there is much existent literature on the return to work process, far less attention has been paid to the employment outcomes and cost effectiveness of interventions. This paper highlights the interventions for musculoskeletal conditions such as lower back conditions that may result in positive employment outcomes, with implications for practice. However, it also highlights gaps in evidence on the employment outcomes and cost effectiveness of interventions for cardio-respiratory (heart and breathing) and mental health conditions.
Restructuring quality assurance frameworks
Authors: Noda Ayaka , Hou Angela Yung Chi , Shibui Susumu , Chou Hua-Chi 
Published: July 2018

PurposeThe purpose of this paper is to examine how the Japanese and Taiwanese national quality assurance (QA) agencies, National Institution for Academic Degrees and Quality Enhancement (NIAD-QE) and Higher Education Evaluation and Accreditation Council of Taiwan (HEEACT), transform their respective frameworks in response to social demands, and analyze and compare the respective approaches for the key concepts of autonomy, accountability, improvement and transparency.Design/methodology/approachUsing a qualitative document analysis approach, this paper initially examines the higher education system, major policies and QA developments, after which the methods associated with the QA restructuring transformations are outlined in terms of motivations, expectations and challenges. Finally, the NIAD-QE and HEEACT evaluation policies and frameworks are compared to assess how each has prepared to respond to emerging challenges.FindingsDuring the QA framework restructuring, both the NIAD-QE and HEEACT struggled to achieve autonomy, accountability, improvements and transparency. While the new internal Japanese QA policy is assured through the external QA, the Taiwanese internal QA, which has a self-accreditation policy, is internally embedded with university autonomy emphasized. The QA policies in both the NIAD-QE and HEEACT have moved from general compliance to overall improvement, and both emphasize that accountability should be achieved through improvements. Finally, both agencies sought transparency through the disclosure of the QA process and/or results to the public and the enhancement of public communication.Originality/valueThis study gives valuable insights into the QA framework in Asian higher education institutions and how QA has been transformed to respond to social needs.
Hospital service quality as antecedent of patient satisfaction – a conceptual framework
Authors: Swain Swapnarag , Kar Nirmal Chandra 
Published: July 2018

Purpose
The purpose of this paper is to explore dimensions of perceived service quality in hospitals and to develop a conceptual framework showing relationship between hospital service quality, patient satisfaction and their behavioural intention.

Design/methodology/approach
This paper is based on extensive review of existing literature on hospital service quality, patient satisfaction and behavioural intention. Critical analysis of these literature studies has resulted in determining and defining the dimensions of perceived service quality and establishing relationship between hospital service quality, patient satisfaction and behavioural intention.

Findings
This study has identified six major areas through which patients perceive quality of service in hospitals. These six areas are technical quality, procedural quality, infrastructural quality, interactional quality, personnel quality, social support quality. Further 20 dimensions of hospital service quality are identified under these 6 major areas. These are clinical procedure, quality of outcome, admission, discharge, waiting time, patient safety, billing and price, follow-up, ambience, availability of resources, accessibility, food, staff attitude, personalised attention, information availability, staff competency, trustworthiness, staff diversity, hospital image and social responsibility. The conceptual framework proposes direct relationship between service quality, patient satisfaction and behavioural intention.

Originality/value
Though many studies have been conducted on hospital service quality, none of them has been able to project all the possible dimensions to measure the same. The “6-Q framework” developed by this study explores all the possible dimensions of perceived service quality in hospitals.
Exporting by experiential knowledge: a study of emerging market micro firms
Authors: Tiwari Sudip K. , Korneliussen Tor 
Published: July 2018

PurposeRelying on the theoretical lens of a knowledge-based view, the purpose of this study is to explore the sources and roles of experiential knowledge in the rapid internationalisation of an emerging market-based micro export firms (EMMFs).Design/methodology/approachThis is an inductive theory building study, which attempts to understand the “how” and “why” questions. In so doing, the study used nine micro export firms operating in the handicrafts sector of Nepal.FindingsThe findings suggest that internationalisation of resource-poor EMMFs relies on the entrepreneurs’ experiential knowledge, which is mainly acquired through prior experience, social networks and participation in international trade-fairs.Research limitations/implicationsThis study contributes by formulating a number of propositions on the sources and roles of experiential knowledge, which could be tested in pursuit of theory building on micro firms’ internationalisation based in emerging markets.Originality/valueThe paper advances an understanding on the patterns of firms’ internationalisation, and discusses EMMFs’ possibilities to emerge as a faster internationalising firm, so-called “born globals”.
The company in society: when corporate responsibility transforms strategy
Authors: Lahtinen Sonja , Kuusela Hannu , Yrjölä Mika 
Published: July 2018

Purpose
This study aims to identify and analyze the different roles corporate social responsibility (CSR) can play in corporate strategy. By acknowledging that one of the biggest challenges for companies in committing to sustainability is the strategy work, the authors outline specific strategic initiatives to achieve these roles and the strategic outcomes that will follow such initiatives.

Design/methodology/approach
Four illustrative case examples show how companies are recasting the role of CSR. The new CSR roles are characterized through two strategic dimensions: an inside-out (firm-oriented) vs outside-in (market-oriented) orientation and an emphasis on leveraging vs an emphasis on prospecting activities.

Findings
The findings show that to realize the opportunities of CSR for business, the environment and society at large, the role of CSR in the boardroom must be reconfigured. By recasting its role, CSR can become a driver for the strategy process and a transformative force generating strategic changes.

Practical implications
This paper aims to encourage top executives to take a proactive stance toward responsibility, recognize the new roles and potential impact that CSR can have in corporate strategy and assist strategic decision-making regarding CSR.

Originality/value
The paper aims to move beyond integrating sustainability into existing strategies and business models by demonstrating how sustainability can also inspire strategic changes a priori when the role of CSR is recast in companies. By viewing CSR as a driver of corporate strategy and strategic initiatives, the authors suggest that besides helping the environment, the community and society, CSR can take care of corporate strategy.
Evaluation of Satellite‐Derived Rainfall Data for Multiple Physio‐Climatic Regions in the Santiago River Basin, Mexico
Authors: Ávila‐Carrasco J.R. , Júnez‐Ferreira H.E. , Gowda P.H. , Steiner J.L. , Moriasi D.N. , Starks P.J. , Gonzalez J. , Villalobos A.A. , Bautista‐Capetillo C. 
Published: July 2018

AbstractAssessment of water resources requires reliable rainfall data, and rain gauge networks may not provide adequate spatial representation due to limited point measurements. The Tropical Rainfall Measuring Mission (TRMM) provides rainfall data at global scale, and has been used with good results. However, TRMM data are an indirect measurement of rainfall, and therefore must be validated for its proper use. In this work, a validation scheme was designed and implemented to compare the TRMM Version 7 (V7) monthly rainfall product at different time frames with data measured in two hydrologic subregions of the Santiago River Basin (SRB) in Mexico: Río Alto Santiago and Río Bajo Santiago (RBS). Additionally, three physio‐climatic regions provide an assessment of the interplay of topography, distance from coastal regions, and seasonal weather patterns on the correspondence between both datasets. The TRMM V7 rainfall product exhibited good agreement with the rain gauge data particularly for the RBS and for the whole SRB during wettest summer and autumn seasons. However, strong regional dependence was observed due to differences in climate and topography. Overall, in spite of some noted underestimations, the monthly TRMM V7 rainfall product was found to provide useful information that can be used to complement limited monitoring as is the case of RBS. An improved combined rainfall product could be generated and thus gaining the most benefits from both data sources.
Description, natural history and genetic variation ofCaloptilia guacanivorasp. nov. Vargas‐Ortiz & Vargas (Lepidoptera: Gracillariidae) in the Atacama Desert, Chile
Authors: Vargas‐Ortiz Marcelo , Gonçalves Gislene L , Huanca‐Mamani Wilson , Vargas Héctor A , Moreira Gilson R P 
Published: July 2018

AbstractAlthough considered the driest desert in the world, the Atacama provides unique habitats and a reservoir of biodiversity for plants and insects.CaloptiliaHübner, 1825 (Gracillariinae), is a highly diverse genus of leaf miner micromoths that has not yet been recorded in Chile. In this study, we describe a new species ofCaloptiliafrom a relict, vulnerable ecotone in the transverse valleys of the Atacama Desert in northern Chile. Adults, immature stages and natural history, including the mine ofCaloptilia guacanivoraVargas‐Ortiz & Vargas sp. nov., are described and illustrated. The larva is a leaf miner of the vulnerable, native, guacano treeMorella pavonis(Myricaceae). DNA barcode sequences were used to infer the specific status ofC. guacanivorasp. nov. Results indicate that the new species is monophyletic with a genetic distance of around 5% to the nearest congener. We also used genetic variation to make preliminary inferences on the population structure and demography of this new taxon. This data revealed the presence of haplotypes shared among distant valleys, suggesting an ancient polymorphism that is widespread throughout populations in the region.