bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cocaine-associated Chest Pain: Our Experience with Myocardial Markers and Stress Lexiscans
Authors: Mohsin Naveed , Pekler Gerald , Mushiyev Savi 
Published: November 2024

Abstract

Background:
Cocaine is a commonly abused recreational drug, leading to frequent emergency room visits. The aim of this study was to check the effect of cocaine on myocardial markers of injury and the stress myocardial imaging patterns.

Materials and Methods:
All patients with anginal chest pain or equivalents who tested positive for cocaine on urine drug screen with reversible myocardial ischemia on regadenoson stress myocardial perfusion imaging called lexiscans were included and their corresponding myocardial markers of injury and stress imaging were reviewed.

Results:
Thirty-four patients had tested positive for cocaine in urine, out of the 192 patients with reversible myocardial ischemia on stress testing. The percentage of cocaine-associated myocardial ischemia was up to 17.70% in our study. Creatine kinase-MB levels were above the normal reference value of 5 ng/mL in 72.7% of patients and the combined cardiac troponins by fourth-generation assays were above the detection levels (≥0.02 ng/mL for cardiac troponin I [cTnI] and ≥0.010 ng/mL for cardiac troponin T [cTnT]) in 50% of patients. None of our patients had severe reversible myocardial ischemia on lexicans, but rather minimal-to-mild reversible myocardial ischemia was seen in the majority (76.5%) of patients. cTnI elevation was significantly associated with minimal reversible myocardial ischemia on one-way analysis of variance (P < 0.05).

Conclusion:
Cocaine was associated with minimal-to-mild reversible myocardial ischemia on stress testing with significant elevation of cTnI.
Bilateral vitreous and retinal hemorrhage associated with immune thrombocytopenic purpura and systemic lupus erythematosus followed by neovascularization
Authors: Lin Chen-Wei , Wang Jin-Jhe , Chang Yu-Cheng , Chen Kuan-Jung , Lai Chien-Hsiung , Chen Ching-Lung 
Published: November 2024

Abstract
Systemic lupus erythematosus (SLE) is known for its diverse clinical manifestations, with hematological problems occasionally overlooked due to mild symptoms. This case report presents a 15-year-old girl with bilateral blurred vision resulting from severe retinal and vitreous hemorrhage secondary to SLE. Following the resolution of hemorrhage, neovascularization developed in one eye and was successfully treated with intravitreous injections of ranibizumab. This case highlights the significance of considering blood dyscrasia disorders in cases of intraocular hemorrhage and underscores the ocular manifestations and potential complications associated with SLE. Timely diagnosis and appropriate management are vital for preserving vision in such cases.
Comparison of magnification corrected optic disc size by slit-lamp biomicroscopy, fundus photography, and optical coherence tomography
Authors: Thomas Linya , Kulkarni Chidanand , Kuzhuppilly Neetha I. R. 
Published: November 2024

Abstract

PURPOSE:
Optic disc size measurement is essential for determining landmarks, lesions, and distances of the retina. Due to the size variability in nature and when measured with different instruments, newer methods to compare sizes between different instruments are needed. We aimed to determine the comparability of slit lamp, fundus photography, and optical coherence tomography (OCT) measurements of optic disc size after correcting for both ocular and instrument magnification.

MATERIALS AND METHODS:
In this prospective, observational study, optic disc size was measured by slit-lamp biomicroscopy, fundus photography, and OCT. Instrument and ocular magnification was calculated, and the measured size was corrected for both using the Littman formula. The corrected values were analyzed using Bland–Altman plots and intra-class correlation (ICC) for agreeability and correlation, respectively. Linear regression analysis was conducted to estimate the systematic errors and interconvertibility in cases of high correlation.

RESULTS:
Fifty-six eyes were included for the analysis. Uncorrected and corrected values for each method had excellent correlation and agreeability (ICC absolute agreement >0.75, P < 0.01). Among magnification corrected values, slit lamp and OCT had excellent correlation and agreement (ICC consistency = 0.846, confidence interval 0.75–0.91, P < 0.01). This pair had R
2 = 0.73 on linear regression (P < 0.01). Linear regression formulas for interconverting uncorrected and corrected values for the three methods had variable accuracy (R
2 from 0.47 to 0.66).

CONCLUSION:
Uncorrected values of different methods for disc size measurement cannot be compared directly; they need ocular and instrument magnification correction. Among the three methods compared, the best interconvertible pairs of measurement were magnification corrected slit lamp and OCT values.
Choroid vascular index in myopic patients – A mini review
Authors: Chi Sheng-Chu , Huang Yi-Ming 
Published: November 2024

Abstract
Myopia has become a globally prevalent ocular disease. The choroid plays a vital role in myopia, and its changes tend to occur earlier than those of the retina and long-term variations in eye growth. Abnormal axial growth is an intrinsic characteristic of myopia, accompanied by ocular biomechanical changes that result in chorioretinal atrophy, thinning, and other complications particularly in the choroidal vasculature. Recent advancements in imaging technologies have provided deeper insights into these changes. This article explores key findings related to the choroid vascular index in myopia patients.
Competencias investigativas del docente. Una construccion desde los programas nacionales de formación
Authors: Albarrán Blanca Margarita 
Published: November 2024

Un docente investigador hace referencia a los conocimientos, destrezas y valores que habilitan, para realizar procesos de investigación de manera efectiva. La modalidad utilizada es informe de investigación cualitativa, describe una investigación concluida bajo el paradigma Interpretativo con una perspectiva socio construccionista y, el método fenomenológico – hermenéutico. Estuvo orientada a develar los significados que los docentes otorgan a las competencias investigativas desde los Programas Nacionales de Formación, en la Universidad Politécnica Territorial “Andrés Eloy Blanco” (UPTAEB).Esta narrativa se despliega en cuatro aspectos: a) Introducción donde se presenta la situación problemática b) Metodología que sustenta el estudio) Hallazgos configurado por la codificación y categorización de la información y c) Reflexiones que llevan a sostener que: Las competencias investigativas van más allá de transmitir un procedimiento o técnica, promueven habilidades científicas, valores y destrezas tecnológicas esenciales en la universidad actual. Participar en redes de investigación a todos los niveles es esencial para el desarrollo académico y profesional.
Data Analytics On Web-Based Document Notification System
Authors: Rose Mae U. Reyes Joana , V. Origines Jr Domingo 
Published: November 2024

This study aimed to address the inefficiencies associated with manual document submission by providing and implementing data analytics within a web-based document notification system. The project also aimed to deliver a user- friendly data analytics dashboard, presenting submitted document data through various visualizations such as count metrics, bar graphs, and tables. This approach holds promise in enhancing decision-making processes, operational efficiency, communication, and collaboration within organizations. Descriptive data analytics methodology was employed to effectively summarize and present data points. Moreover, the project adopted the Rapid Application Development methodology for its development. The project received favorable evaluations from its assessors, attaining high ratings with an overall mean score of 4.17 for functionality, 3.95 for reliability, and 3.98 for usability. Consequently, it successfully achieved its objective of integrating descriptive data analytics into the document notification system. This implementation notably benefited the Human Resource Management Office of Davao del Sur State College by furnishing an analytical dashboard equipped with visualizations such as count metrics, bar graphs, and tables. Furthermore, the system facilitated seamless information updates, empowering administrators to make evidence-based decisions and discern trends within their data.
The intersection of financial modeling and public health: A conceptual exploration of cost-effective healthcare delivery
Authors: Stephane Jean Christophe Zouo  , Jeremiah Olamijuwon  
Published: November 2024

This review paper explores the intersection of financial modeling and public health, highlighting the importance of cost-effective healthcare delivery in contemporary health systems. Financial modeling serves as a crucial tool for policymakers, providing evidence-based insights that inform decision-making and optimize resource allocation. Key financial models, including cost-benefit analysis and predictive modeling, are examined for their applications in public health initiatives, particularly in areas such as preventive care and chronic disease management. The paper discusses core public health priorities—prevention, access, and quality—and the economic constraints faced by healthcare systems. Recommendations are provided for policymakers and healthcare professionals to enhance the application of financial models, emphasizing the need for training, investment in data infrastructure, and fostering cross-sector collaborations. By leveraging financial modeling, public health systems can achieve improved health outcomes while maximizing resource efficiency, ultimately contributing to a more sustainable and equitable healthcare landscape..
Keywords: Financial Modeling, Public Health, Cost-Effectiveness, Healthcare Delivery, Resource Allocation, Preventive Care.
IHT tentang Pembelajaran Berdiferensiasi dan Berlitnum (Berpikir Literasi Numerasi) di SD Negeri Pranggang 3 Plosoklaten Kediri
Authors: Sulistyono Bambang Agus , Handayani Aprilia Dwi , Santia Ika , Hima Lina Rihatul , Samijo Samijo , Yohanie Dian Devita 
Published: November 2024

Latar Belakang: Pembelajaran di sekolah dasar seringkali dihadapkan pada tantangan untuk mengakomodasi perbedaan kemampuan siswa. Pembelajaran Berdiferensiasi dan Berpikir Literasi Numerasi (Berlitnum) merupakan strategi yang diperlukan guna menjawab tantangan ini. Tujuan: Program ini bertujuan untuk melatih guru dalam penerapan Pembelajaran Berdiferensiasi dan Literasi Numerasi, yang diselenggarakan oleh tim dari Universitas Nusantara PGRI Kediri bekerja sama dengan mitra SD Negeri Pranggang 3 Plosoklaten Kediri. Metode: Pelatihan dilaksanakan dengan metode In House Training (IHT) yang melibatkan enam dosen dan dua mahasiswa. Kegiatan terdiri dari penyampaian teori, simulasi, pendampingan, dan evaluasi implementasi. Hasil: Berdasarkan survei kepuasan, pelatihan mendapatkan skor rata-rata kepuasan 90%, dengan kualitas penyampaian fasilitator mencapai skor 96%, dan pemahaman guru mengenai konsep diferensiasi sebesar 94%. Selain itu, implementasi strategi pembelajaran di kelas menunjukkan peningkatan kemampuan literasi numerasi siswa sebesar 15%, berdasarkan hasil pre-test dan post-test yang dilakukan sebelum dan sesudah pelatihan. Kesimpulan: Program PKM ini memberikan dampak positif terhadap peningkatan kemampuan guru dalam mengimplementasikan strategi diferensiasi dan literasi numerasi di kelas.
Penerapan Sabtu Literasi Menggunakan Buku Cerita Rakyat Mampu Meningkatkan Minat Baca Siswa Sekolah Dasar
Authors: Sari Sheryn Dewati Kartika 
Published: November 2024

Penelitian ini dilatar belakangi oleh rendahnya minat baca siswa pada penerapan Gerakan Literasi Sekolah (GLS), sehingga program tersebut tidak berjalan dengan maksimal. Tujuan penelitian ini adalah meningkatkan minat baca siswa menggunakan buku cerita rakyat melalui penerapan sabtu literasi di kelas II. Penelitian ini menggunakan metode Penelitian Tindakan Kelas (PTK) yang melalui 2 siklus yang melibatkan tahap perencanaan, pelaksanaan, observasi, dan refleksi. Penelitian tindakan kelas ini direncanakan dalam dua siklus, dimana setiap siklus terdiri dari 2 pertemuan. Hasil penelitian menunjukkan bahwa keterlaksanaan proses pelaksanaan penerapan sabtu literasi dengan buku cerita rakyat dapat meningkatkan minat baca siswa yang menunjukkan pada siklus I mencapai rata-rata sebesar 62,1%, sedangkan pada siklus II sebesar 82,5%. Berdasarkan hasil tersebut dapat disimpulkan bahwa penerapan sabtu literasi dengan buku cerita rakyat dapat meningkatkan minat baca siswa di kelas II SDN Karangrejo 03.
Viabilidade do controle glicêmico no Diabetes Mellitus Tipo 2 com células-tronco mesenquimais: revisão integrativa
Authors: Gaião Wyndly Daniel Cardoso , Silva Laerte José de Souza , Gomes Hugo Vítor Queiroz , Chaves Anna Karoline da Silva , Bacelar Vera Kaissa Souza Santos , Franco Eryvelton de Souza , Silva Marcia Bezerra da , Maia Maria Bernadete de Sousa 
Published: November 2024

A diabetes mellitus tipo 2 (DM2) é uma condição metabólica caracterizada principalmente pela resistência à insulina e pelo aumento dos níveis de glicose no sangue. As células-tronco mesenquimais (CTMs) são células multipotentes com capacidade de diferenciação em tecidos mesenquimais e possivelmente não mesenquimais, destacando-se por sua plasticidade e propriedades imunomoduladoras. Diante desse contexto, com essa revisão de literatura no formato integrativo objetivo-se selecionar material literário nas bases de dados Nacional Library of Medicine (PubMed), Medical Literature Analysis and Retrieval Sistem on-line (MEDLINE via Biblioteca Virtual de Saúde), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILCAS via Biblioteca Virtual de Saúde) e Scopus, para explorar o impacto do uso de células-tronco mesenquimais no controle glicêmico de indivíduos com DM2. De acordo com os resultados, as CTMs mostraram-se como uma opção segura na terapia celular em indivíduos com DM2. No entanto, pesquisas adicionais são necessárias para avaliar a sua utilização e possíveis impactos a longo prazo.
РОЛЬ РЫБОХОЗЯЙСТВЕННОГО СЕКТОРА В ОБЕСПЕЧЕНИИ ПРОДОВОЛЬСТВЕННОЙ БЕЗОПАСНОСТИ
Authors: Е.Е. Гурнак , М.Н. Наливайко 
Published: November 2024

В статье обоснована необходимость оценки и анализа рыбохозяйственного сектора на юге России с учетом состояния и перспектив развития рыбного производства, а также экологической составляющей, обеспечивающей безопасность производимой продукции для потребителей, и выявления системных проблем становления импортонезависимого и технологически суверенного рыбопроизводства на юге Российской Федерации.
Article substantiates the need to assess and analyze the fishery sector in South of Russia, taking into account the state and prospects for development of fish production. As well as environmental component that ensures the safety of manufactured products for consumers, and identifying systemic problems in development of import-independent and technologically sovereign fish industry in South of Russian Federation.
ОПРЕДЕЛЕНИЕ РОЛЕВОГО УЧАСТИЯ ЭКОЛОГИЧЕСКОГО МАРКЕТИНГА В РЕАЛИЗАЦИИ КОНЦЕПЦИИ МАРКЕТИНГА ТЕРРИТОРИИ
Authors: Н.А. Дадаян 
Published: November 2024

В статье детерминирована характерная для текущей ситуации ведущая роль экологического маркетинга в рамках принятия целевых установок устойчивого развития при реализации концепции маркетинга территории. Сделаны выводы относительно того, что для полноценного развития региона, предполагающего рост качества жизни населения, снижения антропогенной нагрузки на окружающую среду и возможности функционирования и роста на пролонгированную перспективу маркетинг территории как направление социально-экономической политики реализуется в виде развертывания концепции экологического маркетинга, в рамках которой зеленым продуктом, предлагаемым целевым аудиториям, выступает сам регион.
Article determines, characteristic of current situation, leading role of environmental marketing in adoption of sustainable development targets in implementation of concept of territory marketing. Conclusions are drawn regarding the fact that for the full-fledged development of region, assuming an increase in quality of life of population, reduction in anthropogenic burden on environment and possibility of functioning and growth for prolonged perspective, marketing of territory, as direction of socio-economic policy, is implemented in form of deployment of concept of environmental marketing, in which the green product offered by target to audience, region itself performs.
ИНФОРМАЦИОННАЯ МОДЕЛЬ РЕГИОНАЛЬНОГО МОНИТОРИНГА УПРАВЛЕНИЯ ДЕНЕЖНЫМИ ПОТОКАМИ СИСТЕМООБРАЗУЮЩИХ ПРЕДПРИЯТИЙ
Authors: Е.В. Добролежа , А.А. Рябченко 
Published: November 2024

Для рациональной организации регионального мониторинга управления денежными потоками системообразующих предприятий актуальным является формирование соответствующей информационной модели, отображающей существенные источники информации и направления движения информационных потоков при реализации процедур мониторинга. Изучение теоретических основ позволило сформировать информационную модель регионального мониторинга управления денежными потоками, которая представляет собой графическое описание движения информации в мониторинге управления денежными потоками. Определены характеристики источников информации и информационных потоков в региональном мониторинге управления денежными потоками системообразующего предприятия. Разработана информационная модель мониторинга управления денежными потоками предприятия, которая определяет структуру информационных потоков, последовательность формирования, обработки и обобщения информации в соответствии с потребностями менеджмента.
For rational organization of regional monitoring of cash flow management of system-forming enterprises, it is relevant to form appropriate information model that displays significant sources of information and directions of information flows during the implementation of monitoring procedures. Study of theoretical foundations made it possible to form an information model of regional monitoring of cash flow management, which is a graphical description of movement of information in monitoring of cash flow management. Characteristics of information sources and information flows in regional monitoring of cash flow management of system-forming enterprise are determined. Information model for monitoring the management of cash flows of enterprise has been developed, which determines the structure of information flows, sequence of formation, processing and generalization of information in accordance with the needs of management.
НАУЧНО-МЕТОДИЧЕСКИЙ ПОТЕНЦИАЛ КОНКУРЕНТОСПОСОБНОСТИ ЛОГИСТИЧЕСКИХ ТРАНЗИТНЫХ СИСТЕМ
Authors: А.Н. Бакатин 
Published: November 2024

В статье охарактеризованы узловые точки развития потенциала конкурентоспособности логистических транзитных систем, уникальный потенциал Российской Федерации в отношении развития логистических операций транзитного профиля, представлено мнение, что управление логистическими потоковыми процессами грузового профиля сегодня уже не сконцентрировано только на складирования и транспорте, это комплексный сервис, приведены группы факторов, интегрированные в понятие логистического потенциала транзитного значения, обоснована необходимость усиления государственной поддержки российской логистики в виде субсидирования части стоимости перевозок, введения режимов налогового послабления для компаний, осуществляющих операции данного профиля, приоритетности развития компаний, внедряющих российские инновационные технологии, а также комплекса иных мер, способных вывести логистику транзитного характера на новый уровень.
Article characterizes the nodal points in development of competitiveness potential of logistics transit systems; characterizes the unique potential of Russian Federation with regard to development of logistics operations of transit profile; opinion that management of logistic flow processes of cargo profile today is no longer concentrated only on warehousing and transport, it is complex service is presented; groups of factors integrated into concept of logistics potential of transit value are given; necessary to strengthen state support of Russian logistics in form of subsidizing part of cost of transportation, tax exemption regimes for companies engaged in operations of profile, priority development of companies that implement Russian innovative technologies, as well as a set of other measures that can bring logistics of transit nature to a new level.
СОВЕРШЕНСТВОВАНИЕ МЕТОДОЛОГИЧЕСКОГО ОБЕСПЕЧЕНИЯ ПРОЕКТОВ ГОСУДАРСТВЕННО-ЧАСТНОГО ПАРТНЕРСТВА В СИСТЕМЕ РЕГИОНАЛЬНОГО ЖИЗНЕОБЕСПЕЧЕНИЯ
Authors: С.С. Змияк , Н.В. Добаева 
Published: November 2024

В статье анализируются проблемы развития одной из важнейших систем жизнеобеспечения региона — лекарственного снабжения населения. В настоящее время для населения малочисленных поселений, составляющих основную часть сельских территорий, лекарственное обеспечение недостаточно доступно. Коммерческая непривлекательность аптечного бизнеса на данных территориях приводит к отсутствию инфраструктуры получения лекарственных средств. Для преодоления данных проблем с помощью функционально-стоимостного анализа изучаются основные препятствия развития аптечного бизнеса на селе, формулируются меры по совершенствованию организации лекарственного обеспечения. Основу данных мер составляют предложения по созданию на основе государственно-частного партнерства регионального консорциума, который будет поддерживать ключевые функции товародвижения лекарств. Реализация широкого комплекса мер поддержке функций товародвижения лекарственных средств силами бюджетных предприятий, выделения финансовых, материальных, кадровых, информационных и других ресурсов на осуществление аптечной деятельности в малонаселенных пунктах повысит привлекательность данной сферы для бизнеса, позволит предоставить населению широкий и доступный ассортимент лекарств.
Article analyzes the problems of development of one of the most important life support systems in region — drug supply of the population. Currently, for population of small settlements that make up the bulk of rural areas, drug provision is not sufficiently available. Commercial unattractiveness of pharmacy business in these territories leads to lack of infrastructure for obtaining medicines. To overcome these problems with help of functional and cost analysis, main obstacles to development of pharmacy business in rural areas are studied, measures are formulated to improve the organization of drug provision. Basis of these measures are proposals to create a regional consortium based on public-private partnership, which will support the key functions of drug distribution. Implementation of wide range of measures to support the functions of distribution of medicines by budgetary enterprises, allocation of financial, material, personnel, information and other resources for implementation of pharmacy activities in sparsely populated areas will increase the attractiveness of this area for business, will provide the population with wide and affordable range of medicines.