bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paths and Technologies in the Life Project of People with Disabilities: International Perspectives and Educational Potential
Authors: Giaconi Catia , Bianco Noemi Del 
Published: August 2018

Abstract
The purpose of this paper was to analyse the core of the quality of life, intended as a complex construct with specific and transversal features. The approach to this issue, by linking it to the great emergency of disability in adulthood, pushes the analysis into deep conceptual pedagogical reflections, which lead the authors’ initial reflections to focus on the theoretical framework related to the quality of life model and subsequently on the identification of some areas of intervention as a tangible application of the quality of life model. New perspectives and innovative potentials for the quality of life of adults with disability are investigated to reach new awareness, which can also be applied in different life contexts. The paper mentions meaningful trajectories, also from the international scene, aiming to guarantee significantly oriented life trajectories.
Exposure to persistent organic pollutants: impact on women’s health
Authors: Wahlang Banrida 
Published: August 2018

AbstractThis literature review focuses on the causal relationship between persistent organic pollutants (POPs) exposure and women’s health disorders, particularly cancer, cardio-metabolic events and reproductive health. Progressive industrialization has resulted in the production of a multitude of chemicals that are released into the environment on a daily basis. Environmental chemicals or pollutants are not only hazardous to our ecosystem but also lead to various health problems that affect the human population worldwide irrespective of gender, race or age. However, most environmental health studies that have been conducted, until recently, were exclusively biased with regard to sex and gender, beginning with exposure studies that were reported mostly in male, occupational workers and animal studies being carried out mostly in male rodent models. Health-related issues pertaining to women of all age groups have not been studied thoroughly and rather disregarded in most aspects of basic health science research and it is therefore pertinent that we address these limitations in environmental health. The review also addresses studies looking at the associations between health outcomes and exposures to POPs, particularly, polychlorinated biphenyls (PCBs), dioxins and pesticides, reported in cohort studies while accounting for gender differences. Considering that current levels of POPs in women can also impact future generations, informative guidelines related to dietary patterns and exposure history are needed for women of reproductive age. Additionally, occupational cohorts of highly exposed women worldwide, such as women working in manufacturing plants and female pesticide applicators are required to gather more information on population susceptibility and disease pathology.
Differences in the Electromyographic Activity of the Hamstring, Gluteus Maximus, and Erector Spinae Muscles in a Variety of Kinetic Changes
Authors: Hirose Norikazu , Tsuruike Masaaki 
Published: August 2018

Abstract
Hirose, N and Tsuruike, M. Differences in the electromyographic activity of the hamstring, gluteus maximus, and erector spinae muscles in a variety of kinetic changes. J Strength Cond Res 32(12): 3366–3372, 2018—This study aimed to clarify the differences in the electromyographic (EMG) activity of the semitendinosus (ST), semimembranosus (SM), biceps femoris long head (BFl), gluteus maximus (GM), and erector spinae (ES) muscles during leg curl and bridge exercises across different knee angles and isometric contraction outputs. Sixteen male volunteers participated in this study. The EMG of all targeted muscles was measured at 20 and 40% of the maximal voluntary isometric contraction (MVIC) in the leg curl and during bilateral and unilateral bridge exercises. The knee flexion angle was randomly set at 30, 60, 90, and 120° during each of the exercises. The obtained data were normalized by the MVIC of the corresponding muscle, and each of the normalized values was compared with that of the ST. The EMG activity of the ST was significantly greater at 120° of knee flexion than that of 30 and 60° of knee flexion during leg curl regardless of intensity (p < 0.05), in contrast with that of the SM and BFl. However, bridge exercises diminished this inverse relationship. The ES activity changed similarly to that of the hamstrings, and no difference was observed in the activity of the GM regardless of different knee angles during bridge exercise(s). The strength and conditioning professionals should alter the knee joint angle and load during bridge and leg curl exercises according to which hamstring muscle they want to strengthen because ST, SM, and BFl EMG activity varies depending on the intensity and knee angles during these exercises.
Endothelial Vasodilation After a High-Volume Training Load and Tapered Training in Collegiate Female Swimmers
Authors: Weihl Fawn M. , Van Guilder Gary P. 
Published: August 2018

Abstract
Weihl, FM and Van Guilder, GP. Endothelial vasodilation after a high-volume training load and tapered training in collegiate female swimmers. J Strength Cond Res 35(3): 811–818, 2021—High-volume endurance training loads have been linked to adverse remodeling of the heart and large arteries; yet, data on the vascular endothelial function are unclear. Moreover, although collegiate-level endurance athletes often perform high-volumes of vigorous endurance training and resistance training as part of their strength and conditioning programs, it is unknown whether they also experience vascular abnormalities, particularly changes in endothelial function. The aim of this study was to verify the impact of a high-volume training load phase followed by low-volume tapered training on endothelial vasodilator function in National Collegiate Athletic Association (NCAA) Division I competitive female swimmers. Microvascular endothelial vasodilation was assessed by pulse arterial tonometry that provides a reactive hyperemia index in 10 female NCAA Division 1 swimmers after 4 weeks of a high-volume training load, and subsequently, after 3 weeks of low-volume tapered training as part of preparation for annual conference championships. The reactive hyperemia index was calculated as the ratio of the pulse volume amplitude after 5 minutes of left-arm brachial artery ischemia to the baseline amplitude, divided by same ratio in the contralateral arm. The high-volume training load included a 4-week block of dual-day sessions (120 minutes per practice) consisting of vigorous intensity endurance and high-intensity interval/sprint swim training, coupled with 5K running, resistance training, and Olympic weightlifting. Tapered training consisted of 3 weeks of 3–5 swims per week at ∼50% V̇o
2max for 60 minutes per practice (∼4,000 minutes per practice). The reactive hyperemia index (1.73 ± 0.50) was low in athletes after the high-volume training load with 8 athletes demonstrating endothelial dysfunction. However, after tapered training, the reactive hyperemia index was ∼33% higher (2.29 ± 0.43; 95% confidence interval [CI]: 1.98–2.60, p = 0.0223 vs. the high-volume training load). Effect size, as expressed by the partial eta2 (0.46) and Cohen's d
z (1.1923; 95% CI: 0.1687–2.4643) with tapered training, was large. These results demonstrate distinct differences in endothelial vasodilation after 4 weeks of a high-volume training load compared with a 3-week taper in NCAA Division I female swimmers.
Sociodemographic Factors and Survival of Infants With Congenital Heart Defects
Authors: Pace Nelson D. , Oster Matthew E. , Forestieri Nina E. , Enright Dianne , Knight Jessica , Meyer Robert E. 
Published: August 2018

OBJECTIVES:
To examine the first-year survival of infants with congenital heart defects (CHDs) and investigate the potential role of socioeconomic and demographic factors on survival.

METHODS:
Subjects included 15 533 infants with CHDs born between 2004 and 2013 ascertained by the NC Birth Defects Monitoring Program. We classified CHDs into the following 3 groups: critical univentricular (n = 575), critical biventricular (n = 1494), and noncritical biventricular (n = 13 345). We determined vital status and age at death through linkage to state vital records and used geocoded maternal residence at birth to obtain census information for study subjects. We calculated Kaplan–Meier survival estimates by maternal and infant characteristics and derived hazard ratios from Cox proportional hazard models for selected exposures.

RESULTS:
Among all infants with CHDs, there were 1289 deaths (8.3%) in the first year. Among infants with univentricular defects, 61.6% (95% confidence interval [CI]: 57.7%–65.7%) survived. Survival among infants with univentricular defects was considerably better for those whose fathers were ≥35 years old (71.6%; 95% CI: 63.8%–80.3%) compared with those whose fathers were younger (59.7%; 95% CI: 54.6%–65.2%). Factors associated with survival among infants with any biventricular defect included maternal education, race and/or ethnicity, marital status, and delivery at a heart center. The hazard of infant mortality was greatest among non-Hispanic African American mothers.

CONCLUSIONS:
Survival among infants with critical univentricular CHDs was less variable across sociodemographic categories compared with survival among infants with biventricular CHDs. Sociodemographic differences in survival among infants with less severe CHDs reinforces the importance of ensuring culturally effective pediatric care for at-risk infants and their families.
Penerapan Model Pembelajaran Kooperatif dengan Strategi Make A Match untuk Meningkatkan Kemampuan Komunikasi Matematika Siswa
Authors: Nurani Sujana Laeli Dwi , Juariah Juariah , Karso Karso , Kariadinata Rahayu 
Published: August 2018

Komunikasi di dalam proses belajar sangat diperlukan karena komunikasi merupakan sesuatu yang utama dalam mengajar, menilai dalam pembelajaran matematika serta memudahkan dalam menyelesaikan permasalahan. komunikasi matematik mencakup beberapa hal yaitu kemampuan menulis, membaca, diskusi, evaluasi, dan berwacana. Disamping itu yang perlu diperhatikan adalah model pembelajaran yang diterapkan guna menghadapi era globalisasi. Untuk meningkatkan hasil belajar siswa salah satu model yang dapat digunakan dalam pembelajaran adalah Make a Match. Make a Match atau mencari pasangan merupakan salah satu alternatif yang dapat diterapkan kepada siswa
COMPARATIVE IMMUNOHISTOCHEMICAL EVALUATION OF E-CADHERIN AND Β-KATENIN EXPRESSION IN METASTATIC AND NON-METASTATIC BREAST CANCER OF NON-SPECIFIC TYPE
Authors: Mnikhovich M. V. , Kakturskiy L. V. , Bezuglova T. V. , Midiber K. Yu. , Bun’kov K. V. , Erzieva A. G. 
Published: August 2018

Objective:an immunohistochemical analysis of the features of expression, distribution and interaction of E-сadherin and β-сatenin proteins in primary mammary tumors.Materials and methods.The study group consisted of 148 relevant patients with breast cancer (BC), including patients with metastases in lymph nodes (n = 12) and liver (n = 45). E-сadherin and β-сatenin expression on BC cells was determined using immunohistochemical method with specific antibodies.Results.It was shown that the reduction and the total absence of E-сadherin expression was observed much more often in patients with BC with metastases in liver, than in patients without metastases (70 % of cases versus 30 % of cases respectively). An increase of cytoplasmic immune reactivity and a nuclear translocation of β-сatenin are found in more than 80 % cases of BC with metastases.Conclusion.The changes in the expression of E-сadherin and β-сatenin in tumor cell can be considered as factors of a non-favorable prognosis of BC. The emergence of β-сatenin expression indicates the activation of a signaling pathway which is triggered by the aberrant expression of epithelial cadherins leading to an increased mobility and invasion of tumor cells.
Comparative effectiveness of avelumab versus chemotherapy in Merkel cell carcinoma: innovative use of patient insights
Authors: Bharmal Murtuza , Marrel Alexia , Hennessy Meliessa , Fofana Fatoumata , Lambert Jérémy , Arnould Benoit 
Published: August 2018

Aim:
To assess patient experience with chemotherapy and avelumab in metastatic Merkel cell carcinoma (mMCC).
Methods:
In the JAVELIN Merkel 200 trial, chemotherapy-refractory mMCC patients could participate in optional qualitative interviews at baseline documenting recollection of previous chemotherapy experience, and at weeks 13/25 documenting current experience with avelumab. Functional Assessment of Cancer Therapy subscale for melanoma questionnaire (FACT-M) was administered in parallel.
Results:
In our sample, chemotherapy was associated with an unpleasant experience. On selected FACT-M items addressing chemotherapy-impacted concepts, most patients receiving avelumab were improved or stable; few worsened. In addition, a few patients spontaneously reported experiencing less toxicity with avelumab than experienced during previous chemotherapy.
Conclusion:
This approach merging qualitative and quantitative data suggests that mMCC patients report a better experience with avelumab than with chemotherapy.
A ESCOLA RURAL MULTISSERIADA SOB O PRISMA DA EDUCAÇÃO DO CAMPO E DA ETNOMATEMÁTICA
Authors: Figueirêdo Tânia Maria Mares , Andrade Luciana Gomes , Pereira Pedro Carlos 
Published: August 2018

O presente artigo tem por objetivo discutir a importância dos princípios da Educação do Campo e dos conceitos básicos da Etnomatemática em Escolas Rurais Multisseriadas. Acreditamos que o ensino nessas escolas deve manter o diálogo contínuo com os diferentes contextos dos territórios do campo onde o trabalho e a cultura façam parte dos saberes e fazeres escolares. O trabalho ora apresentado faz parte de um estudo realizado pelo grupo de pesquisadores da APEJE – Associação de Professores e Pesquisadores em Educação e Desenvolvimento do Vale do Jequitinhonha. As escolas rurais pesquisadas fazem parte da Microrregião do Baixo Jequitinhonha, situada no nordeste do Estado de Minas, onde todos os municípios possuem um número significativo de comunidades rurais. As Escolas Rurais Multisseriadas – antes denominada Escola Isolada Rural - são pouco mencionadas, quiçá refletidas, nas literaturas pedagógicas brasileiras, principalmente, no que tange à superação das metodologias de ensino e de aprendizagem tradicionais e arbitrárias, desenvolvidas nas aulas de Matemática. Mesmo com marca centenária na região, a Escola Rural Multisseriada, devido fatores políticos e educacionais, é vista de por muitos, como uma escola atrasada e carente, incapaz de cumprir com seu papel educativo, por isso negada pela sociedade urbana e isolada pelos órgão públicos. Todavia, há muito o saber e compreender sobre o cotidiano dessa escola a fim de propor mudanças estruturais que vão deste a qualificação dos docentes a uma proposta curricular que dialogue com as necessidades das comunidades em seu entorno. Para tanto, faz-se necessário trilhar novos caminhos metodológicos para o ensino de Matemática, sob o prisma da Educação do Campo e da Etnomatemática, a fim de superar dilemas didático-pedagógicos que a muito tempo estão presentes nas Escolas Rurais Multisseriadas do Baixo Jequitinhonha.
A EXPERIMENTAÇÃO NAS AULAS DE CIÊNCIAS: ESTRATÉGIA PARA ALFABETIZAÇÃO CIENTÍFICA NO ENSINO FUNDAMENTAL.
Authors: Arial Bernardo Flávia Pirovani , Gonçalves Agda Felipe Silva , Werner Elias Terra 
Published: August 2018

O presente relato de experiência apresenta um projeto de ensino intitulado “O método científico através da experimentação na sala de aula” realizado com alunos do 4º e 5º anos do ensino fundamental afim de promover reflexões sobre como a experimentação pode contribuir com o processo de alfabetização científica. Através da utilização de dois experimentos, um sobre o ciclo da água e outro sobre deslizamentos de encostas, objetivou-se a apresentação aos alunos das etapas do método científico e realização de reflexões sobre os resultados observados com circunstâncias do cotidiano dos alunos. As atividades foram realizadas de maneira lúdica e descontraída afim de obter a participação de todos os alunos. Foi observado o progresso dos alunos durante as aulas do projeto e a familiarização com o conteúdo apresentado. A relação dos temas abordados foi facilmente estabelecida com a realidade local a partir da apresentação dos experimentos permitindo a leitura dos fenômenos estudados. A utilização dos experimentos e das demonstrações facilitaram a visualização e tornou o momento atrativo, demonstrando que atividades como estas que foram desenvolvidas podem facilitar a leitura do que acorre na natureza de maneira reflexiva e crítica.
POSSÍVEIS INDICADORES DE INVARIANTES OPERATÓRIOS PERTINENTES AOS CAMPOS CONCEITUAIS DA ELETRODINÂMICA E PROPORCIONALIDADE NO ENSINO MÉDIO INTEGRADO
Authors: Bopp Antonello Suziane , Garcia Isabel Krey Garcia , Santarosa Maria Cecília Pereira Santarosa , Clavé Baggio Giliane Höer , De Lopes Jean Lucas Lopes 
Published: August 2018

Este trabalho apresenta uma atividade que foi aplicada em uma turma de 36 alunos do primeiro ano de um Curso Técnico em Eletrotécnica Integrado ao Ensino Médio. A atividade objetivou verificar alguns indicadores de possíveis invariantes operatórios pertinentes aos campos conceituais da Eletrodinâmica, Proporcionalidade e Função demonstrados pelos alunos e apresentar situações nas quais os alunos manipularam instrumentos para realizar medições, utilizaram-se do computador munido de software Excel para plotar valores e construir gráficos e formalizar o conceito de Função e suas representações. As situações foram desenvolvidas nos Laboratórios de Eletrônica e de Informática. Foram aplicados dois instrumentos de avaliação: um antes e um depois da atividade. Analisar os conhecimentos prévios permitiu conhecer sobre possíveis indicadores de invariantes operatórios demonstrados pelos alunos sobre alguns conceitos presentes nos campos conceituais considerados no estudo. Esse mapeamento contribuiu para a apresentação e o desenvolvimento das situações, possibilitando direcionar as atividades de forma a propiciar a construção de teoremas-em-ação mais próximos dos cientificamente aceitos, além de servir de base para a construção de novos conceitos, e, por consequência, revelaram evidências de aprendizagem significativa.
PEMETAAN UMKM INDUSTRI KREATIF DI WILAYAH PRIANGAN TIMUR: IDENTIFIKASI KEUNGGULAN DAYA SAING LOKAL
Authors: Purbasari Ratih , Chandra Wijaya , Rahayu Ning , Maulina Erna 
Published: August 2018

ABSTRACT This research tries to improve local competitive advantage through of creative industry potentials development. The research method used is qualitative approach and contextual technique of local competitive advantage development in East Priangan region with the following stages (1) Collecting secondary data through literature review and related intitutions (2) Understanding of local competitive advantage and creative industries concept (3) Mapping creative industries potential (4) Identifying the most potentialy creative industries and analysis. The results showed that the sub-sectors of the most potential creative industry in each region are the Mendong Handicraft Industry (Tasikmalaya City), the Akar Wangi Handicraft Industry (Garut Regency), the Coconut Handicraft Industry (Ciamis Regency) according to the competitive advantage concept. They also have local resources and supported by government protection policies. Moreover they have both domestic and foreign markets. In order to have competitive advantage sustainability, required collaboration and cooperation of all related parties in an entrepreneurial ecosystem of each creative industry regions. Keywords : Local Competitive Advantage, Creative Industry, East Priangan, ABSTRAKPenelitian ini berupaya untuk membantu meningkatkan keunggulan daya saing lokal melalui pengembangan potensi industri kreatif. Metode penelitian yang digunakan adalah pendekatan kualitatif dan teknik kontekstual mengenai pengembangan keunggulan daya saing lokal di wilayah Priangan Timur dengan tahapan (1) Mengumpulkan data sekunder melalui tinjauan pustaka dan institusi terkait (2) Pemahaman konteks keunggulan daya saing lokal dan industri kreatif (3) Pemetaan potensi industri kreatif (4) Identifikasi industri kreatif yang paling berpotensi dan analisisnya. Hasil penelitian menunjukkan bahwa subsektor dari industri kreatif yang paling berpontensi di masing-masing daerah adalah Industri Kerajinan Anyaman Mendong (Kota Tasikmalaya), Industri Kerajinan Akar Wangi (Kab. Garut), Kerajinan Lidi Kelapa (Kab. Ciamis) berdasarkan konsep keunggulan daya saing, memiliki sumber daya lokal dan dukungan kebijakan perlidungan dari pemerintah, serta telah memiliki pasar domestik dan luar negeri. Untuk memiliki keunggulan daya saing berkelanjutan, dibutuhkan kolaborasi dan kerjasama dari semua pihak yang terlibat di dalam ekosistem kewirausahaan di setiap wilayah industri kreatif tersebut.Kata kunci : Keunggulan Daya Saing Lokal, Industri Kreatif, Priangan Tim
PERBANDINGAN KINERJA PASAR PADA BISNIS RETAIL DI PASAR TRADISIONAL SEBELUM DAN SESUDAH KEBERADAAN ALFAMART DAN INDOMARET DI KECAMATAN BATAM KOTA KOTA BATAM
Authors: Hati Shinta Wahyu , Novita Chandra 
Published: August 2018

ABSTRACTThis study aims to determine the average ratio of market performance in traditional retail business before and after the presence of modern retail Alfamart and Indomaret in Batam Kota subdistrict which is spread in three villages, namely Baloi Permai Village, Belian Village and Teluk Tering Village. The sampling technique used in this research is purposive and accidental sampling with questionnaires obtained from 42 respondents. This study using analysis of paired sample t-test. The output of the paired sample t-test showed a response to hypotheses derived from each of the variables studied. Values obtained for before and after sales turnover tcount is equal to 2.398. Values obtained for before and after profit tcount is equal to 2.380. Values obtained for before and after working hours -tcount is equal to -7.879. The results of each tcount then be compared with ttabel where it is known that tcount each variable > ttabel and significance/P-Value <0,05 so that H0 rejected and Ha accepted. These three variables showed significant results that indicate that the presence of Alfamart/Indomaret give the average change impacts on market performance in Batam City District.ABSTRAK Penelitian ini bertujuan untuk mengetahui perbandingan rata-rata kinerja pasar pada usaha ritel tradisional sebelum dan sesudah hadirnya ritel modern Alfamart dan Indomaret di daerah Kecamatan Batam Kota yang menyebar di tiga kelurahan, yaitu Kelurahan Baloi Permai, Kelurahan Belian dan Kelurahan Teluk Tering. Teknik sampling yang digunakan dalam penelitian ini adalah purposive dan accidental sampling dengan kuesioner yang diperoleh dari 42 responden. Penelitian ini menggunakan analisis paired sample t-test. Hasil output dari paired sample t-test menunjukkan jawaban dari hipotesis yang diambil terkait masing-masing variabel yang diteliti. Nilai yang diperoleh untuk thitung omset penjualan sebelum dan sesudah adalah sebesar 2,398. Nilai yang diperoleh untuk thitung laba sebelum dan sesudah adalah sebesar 2,380. Nilai yang diperoleh untuk -thitung jam kerja sebelum dan sesudah adalah sebesar -7,879. Hasil dari masing-masing nilai thitung kemudian akan dibandingkan dengan ttabel dimana diketahui bahwa nilai thitung masing-masing variabel > ttabel dan signifikansi/P-Value < 0,05 sehingga H0 ditolak dan Ha diterima. Ketiga variabel menunjukkan hasil yang signifikan yang menunjukkan bahwa keberadaan Alfamart/Indomaret memberikan dampak perubahan rata-rata pada kinerja pasar di Kecamatan