bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design, synthesis, characterization, and theoretical calculations, along with in silico and in vitro antimicrobial proprieties of new isoxazole-amide conjugates
Authors: Barghady Najoua , Assou Soumia Ait , Er-Rajy Mohammed , Boujdi Khalid , Arzine Aziz , Rhazi Yassine , Tüzün Burak , Nakkabi Asmae , Chalkha Mohammed , El Hassouni Mohammed , Kabra Atul , Alanazi Mohammed M. , Baouid Abdesselam , El Yazidi Mohamed 
Published: October 2024

Abstract
Functionalized isoxazoles provide valuable structural motifs, opening up a wide range of uses in the medicinal, pharmacological, and pharmaceutical fields. Within this scope, an efficient approach has been adopted to synthesize a novel series of functionalized isoxazole derivatives, starting from aza-aurone, providing reproducible access to the desired isoxazoles in excellent yields. All synthesized compounds were structurally elucidated through the use of various spectroscopic techniques and mass spectrometry. The derivatives generated were screened for their antimicrobial potential against the fungus Candida albicans as well as three bacterial strains. The results show that almost all of the tested isoxazole derivatives were found to be significantly potent against the fungus C. albicans. The functionalized isoxazoles were also computed using the Gaussian software package with the 6-31++G(d,p) basis set at B3LYP, HF, and M062X levels, and their chemical activities were compared. Moreover, the molecular docking studies of tested isoxazole compounds were performed against the C. albicans receptor. The results suggest that the newly synthesized compounds exhibit docking scores ranging from −10.29 to −15.08 kcal/mol, revealing a high affinity for the target enzyme (5V5Z). Lastly, drug similarity studies and ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties assessments indicate that isoxazole derivatives have favorable absorption, distribution, and metabolism properties associated with a proven lack of toxicity.
A Hydraulic Gradient and Stress-Controlled Erosion Apparatus for Assessing Soil Internal Erosion
Authors: Marot Didier , Oli Bikram , Bendahmane Fateh , Gelet Rachel , Leroy Philippe 
Published: October 2024

Abstract
Among the four dominant mechanisms of internal erosion, suffusion appears as one of the most complex. It is indeed the result of the combination of three processes: dislodgement of fine particles, transport of them, and filtration of some fluidized fine particles. These processes depend on the soil’s stress state and on the hydraulic gradient path. Thus, to ensure the repeatability of the suffusion test and to study with accuracy the influence of the aforementioned parameters, a new apparatus was developed. This apparatus is designed to test specimens under a vertical downward flow in hydraulic gradient controlled condition while controlling the confining pressure and the stress deviator, which can be either positive or negative. Ten tests on one cohesionless soil were performed in triaxial conditions, with the same mean effective stress and four different values of stress deviator. To compare with conventional suffusion results, one test is also performed in rigid wall conditions. For all performed tests, the same hydraulic gradient path was applied and particular attention is paid to the repeatability, which implies control of each test step. At the end of each test, the specimen was divided into four layers to measure post-suffusion grain size distributions. The time evolutions of the hydraulic conductivity and the erosion rate permit to identify four different phases. Each phase is characterized by two methods: one based on the hydraulic gradient and the second based on the expended energy by the fluid. The results show the great influence on the suffusion kinetics of the preferential flow paths, which localize in the body of the specimen in triaxial conditions and on the circumference in rigid wall ones. Under a constant mean effective stress, the effect of the stress deviator on the suffusion kinetics appears limited, for the tested soil and shear stress ratios.
A Method for Determining Yield Stress of Unsaturated Soils from Lateral Pressure
Authors: Liu Yan , Wang Xiang , Zhao Yuxin , Chen Lihong , Li Xu 
Published: October 2024

Abstract
Predicting the stress–strain behavior of unsaturated soils is essential for determining yield stress. This paper explores a new method for determining the yield stress of unsaturated soils from the lateral pressure curve. A series of earth pressure at rest (K0) ondometer tests were conducted on unsaturated Yangqin silt clay. Lateral stress was obtained under different saturations and compactness. The relationship curves between lateral and vertical net stress were drawn for each condition. An obvious turning point was observed in the curve, which can be used to determine the yield stress. The oedometer tests were conducted, and the Casagrande and the bilogarithmic methods were used for comparison purposes. The difference between the proposed and traditional methods was less than 17 %. The initial saturation and compactness influence on the yield stress was discussed. The yield stress increased with the decrease in saturation and increases in compactness, which is consistent with that of the classic method. The test results and comparison prove the rationality of the proposed method. No coordinate transformation is required in the proposed method, which is more convenient for data processing. It can be used to determine the yield stress of unsaturated soils from another perspective.
Un diagnostic curieux causant une proptose unilatérale : Rapport de cas
Authors: Banister Elyse 
Published: October 2024

Contexte : Le méningiome de l’aile du sphénoïde est l’une des tumeurs extraconiques les plus courantes et peut se présenter de diverses façons. Les méningiomes ont tendance à toucher davantage les femmes que les hommes et à se manifester chez les personnes âgées de plus de 50 ans. Les méningiomes de l’aile du sphénoïde ne nécessitent habituellement pas de traitement, à moins qu’ils ne menacent le nerf optique ou n’envahissent rapidement les structures cérébrales environnantes. Rapport de cas : Une femme de 48 ans se plaint de maux de tête depuis trois ou quatre mois, de douleurs oculaires et d’une « poche de liquide jaune » dans l’œil gauche depuis un mois. L’examen oculaire a révélé une proptose unilatérale de l’œil gauche. La neuro-imagerie a révélé un méningiome de l’aile du sphénoïde gauche. L’orientation vers un service de neurologie a finalement abouti à l’ablation chirurgicale de la lésion intracrânienne. La patiente est actuellement suivie avec des examens neurologiques et optométriques annuels. Ce rapport de cas passe en revue la pathogenèse, le pronostic et la prise en charge des méningiomes sphénoïdaux. Conclusion : Les méningiomes sont considérés comme des lésions bénignes du cerveau. On pensait autrefois qu’ils étaient dus à des variations hormonales, en partie parce qu’ils touchaient davantage les femmes que les hommes. On pense aujourd’hui que les troubles génétiques que sont la neurofibromatose de type 2 et la monosomie 22 sont les coupables, car la plupart des méningiomes contiennent l’une ou l’autre de ces mutations. Une fois que la stabilité de la résection chirurgicale de la tumeur a été établie, la prise en charge comprend un examen annuel des yeux et une neuro-imagerie (par imagerie par résonance magnétique [IRM] ou tomodensitométrie [TDM]).
Prise en charge optométrique des cas liés aux commotions cérébrales en pratique privée au Canada
Authors: Yeboah Anne Marie , Dalton Kristine , Irving Elizabeth 
Published: October 2024

Objectif
Cette étude visait à déterminer les pratiques actuelles de prescription et d’évaluation des optométristes au Canada qui voient des patients ayant des déficits visuels persistants liés aux commotions cérébrales.
Méthodes
Un sondage électronique de six questions a été distribué aux conseils provinciaux et nationaux d’optométrie au Canada. Des questions portant sur l’évaluation de la vision, les habitudes de prescription, les conseils de la vie quotidienne, la durée des rendez-vous et les rendez-vous de suivi ont été inclus. Les optométristes en exercice au Canada qui ont pris en charge ou non des patients ayant subi une commotion cérébrale étaient admissibles à répondre au sondage. L’analyse consistait à catégoriser et à analyser la fréquence des réponses.
Résultats
Au total, 199 réponses ont été reçues, dont 142 étaient complètes (y compris 1 réponse vide). De ce nombre, 13 optométristes ont indiqué qu’ils ne prenaient pas en charge les cas liés aux commotions cérébrales.
Sur les 128 optométristes qui ont indiqué avoir pris en charge des cas liés à une commotion cérébrale, 98 % ont effectué un examen complet de la vue. L’acuité visuelle a été évaluée dans 96 % des cas. Les autres évaluations fréquentes étaient la réfraction sèche (91 %), la dilatation des pupilles (80 %) et la vision binoculaire complète (78 %).
La plupart des répondants (n=116) ont indiqué qu’ils donnaient des conseils sur les activités de la vie quotidienne et que le conseil le plus fréquent consistait à limiter l’activité (74/116, 64 %).
Cent vingt et un optométristes ont fourni une réponse au sujet de la durée des rendez-vous. Le plus souvent, les optométristes ont déclaré que les rendez-vous lorsqu’il s’agissait de commotion cérébrale duraient de 30 à 60 minutes (69/121). Cent dix-neuf optométristes ont donné une réponse au sujet du suivi, qui était le plus souvent de 1 à 2 mois (27/119).
Conclusion
Ces résultats donnent un aperçu de la façon dont les optométristes en pratique privée prennent en charge les déficits de la vision à la suite d’une commotion cérébrale. D’autres recherches sur l’efficacité du traitement seront nécessaires pour élaborer un protocole optométrique pour la prise en charge de la vision chez les patients qui présentent des symptômes post-commotionnels.
Phonon polariton-mediated heat conduction: Perspectives from recent progress
Authors: Li Deyu , Pan Zhiliang , Caldwell Joshua D. 
Published: October 2024

AbstractIt has been well-accepted that heat conduction in solids is mainly mediated by electrons and phonons. Recently, there has been a strong emerging interest in the contribution of various polaritons, quasi-particles resulting from the coupling between electromagnetic waves and different excitations in solids, to heat conduction. Traditionally, the polaritonic effect on conduction has been largely neglected because of the low number density of polaritons. However, it has been recently predicted and experimentally confirmed that polaritons could play significant roles in heat conduction in polar nanostructures. Since the transport characteristics of polaritons are very different from those of electrons and phonons, polariton-mediated heat conduction provides new opportunities for manipulating heat flow in solid-state devices for more efficient heat dissipation or energy conversion. In view of the rapid growth of polariton-mediated heat conduction, especially by phonon polaritons, here we review the recent progress in this field and provide perspectives for challenges and opportunities.
Graphical abstract
African Oystercatcher Haematopus moquini in the Karoo
Authors: Du Toit Jannie , Tippett Ryan M , Underhill Les G 
Published: October 2024

The first record of an African Oystercatcher Haematopus moquini in the Karoo is reported. The bird was a juvenile, and the observation was made c. 330 km from the coast. The date of the observation, 7 July 2024, was during a period of severe storms in the breeding range of the species in the Western Cape, South Africa, and it is likely that the juvenile oystercatcher was driven inland during its migration northwards from its natal territory.
The emergence of labial harmony in Old Hungarian
Authors: Cser András , Oszkó Beatrix , Várnai Zsuzsa 
Published: October 2024

Hungarian displays both backness harmony (inherited from Proto-Uralic) and labial harmony, the latter developing in Old Hungarian. This paper sets out to explain the fact that the emergence of labial harmony, i.e., the progressive spreading of the feature [labial] in Late Old Hungarian results from an apparent change in the earlier regressive direction of spreading for the same feature. The question addressed here is what caused the change in the direction of the spreading. The hypothesis advanced is that Early Old Hungarian regressive spreading of labiality did not affect lexical cues, since [labial] was a redundant feature; the spreading was motivated by coarticulatory mechanisms. However, as [labial] became a robust contrastive feature in the Old Hungarian period, it aligned with backness in its spreading direction to enhance lexical recognisability. The argument also implies that while labial harmony owes its origin to a pattern rooted in coarticulatory mechanisms, in its mature form it acquired a superimposed perceptual motivation.
First Installation of an Optical Ocean-Bottom Seismometer, Cabled Offshore Les Saintes, Lesser Antilles
Authors: Bernard Pascal , Hello Yann , Plantier Guy , Menard Philippe , Savaton Guillaume , Bonnieux Sébastien , Bouin Marie-Paule , Nercessian Alexandre , Feuilloy Mathieu , Feron Romain , Satriano Claudio , Deroussi Sébastien , Moretti Roberto , Sladen Anthony , Roca Jean-Claude , Camusat Mathieu , Rivier Judicaël , Gaucher Bastien , Boudin Frédérick , Kitou Thierry , Didier Tristan , De Chaballier Jean-Bernard , Clouard Valérie 
Published: October 2024

Abstract
The detection and analysis of offshore seismic processes worldwide often require the use of ocean-bottom seismometers (OBSs). However, most OBS deployments are done with stand-alone stations, with data recovery delayed by months. On the other hand, electrically cabled OBS, which allows for real-time monitoring, remains exceptional due to the high cost of manufacturing, installation, and maintenance. Here, we present a new perspective for cabled array of OBSs, using purely optical seismometers, plugged at the end of long fiber-optic cables, aimed at reducing their cost for observatories requesting real-time data. The optical seismometer was developed in the last decade by the École Supérieure d’Électronique de l’Ouest, based on the Fabry–Perot interferometer, tracking at high resolution the displacement of the mobile mass of a mechanical geophone (no electronics nor feedback). A prototype was successfully installed at the top of La Soufrière volcano of Guadeloupe in 2019. We replicated this sensor and installed it 5 km offshore Les Saintes islands, at 43 m depth (Guadeloupe, Lesser Antilles) to characterize the swarm-type activity persistent after the 2004 M 6.3 earthquake (Interreg Caraïbe PREST project). The installation cruise, FIBROSAINTES, was supported by the Flotte Océanographique Française. A plow designed by GEOAZUR carried the cable and was pulled on the seafloor by the vessel ANTEA. The landing cable was connected to the interrogator, with a real-time telemetry to the Institut du Physique du Globe de Paris/Observatoire Volcanologique et Sismologique de Guadeloupe. The OBS has been qualified with local land-based velocity broad band stations. The analysis of local earthquake swarms suggests transient creep on the major normal faults. This successful installation opens promising perspectives for real-time monitoring in on-land or offshore sites, presenting harsh environmental conditions, in which commercial, electrical seismic sensors are difficult and/or costly to install and maintain.
Preliminary Results of a Workplace Health Promotion Program in Higher Education
Authors: Murphy April , Macy Gretchen , Basta Tania 
Published: October 2024

Background: Employees of higher education have an increased risk for stress, burnout, and turnover. Workplace Health Promotion (WHP) programs have been shown to improve quality of life, reduce individual health risks, improve morale, reduce health care costs, and increase employee retention.
Aim: The aim of this study was to determine the impact of a WHP initiative on employee intent to stay, life/work balance, and work-related quality of life.
Methods: This study employed a cross-sectional design at a Midwestern university. All faculty and staff were invited to participate in an Employee Wellness Hour, which allowed them to take an additional hour per day to participate in wellness-related activities. Those who chose to participate were required to track their wellness activity on a weekly basis in Qualtrics and invited to participate in a survey examining their intent to stay, life/work balance, and work-related quality of life. Analyses were conducted to determine whether participation in the Employee Wellness Hour had an impact on employee intent to stay, their life/work balance, and work-related quality of life.
Results: Results indicated that those who participated in the Employee Wellness Hour were more likely to stay with their current employer and rated their working conditions more positively.
Conclusions: The cost of employee turnover is immense, making it imperative that employers develop and implement innovative solutions to retain employees and improve working conditions. This study provided preliminary evidence that WHP programs can have a positive impact on retention and working conditions among those employed in institutions of higher education.
Regional microbial content of fermented traditional and industrial East Mediterranean sausages from the islands of Cyprus and Mytilini
Authors: Kamilari Eleni , Stanton Catherine , Tsaltas Dimitrios , Ross R. Paul 
Published: October 2024

Objective: To characterize the microbial biodiversity of fermented sausages from the East Mediterranean islands of Cyprus and Mytilini, and to identify differences between the microbial diversity of traditionally and industrially produced Cypriot sausages.
Method: The microbial diversity of thirty sausages from Cyprus and Mytilini (traditionally and industrially produced) was analyzed using high throughput sequencing (HTS) (amplicon sequencing) of 16S rRNA gene and ITS loci fragments. By applying microbial signature detection and machine learning algorithms, we identified key microbes that distinguish traditionally produced sausages from those produced industrially. Focusing on selected microbial taxa and using interaction network analysis, we identified associations among the sausages’ microbiota that may affect the shaping of the sausages’ microbial consortia.
Results: Cypriot and Mytilini sausages indicated increased relative representation of Lactobacillus and Leuconostoc . Cypriot sausages were distinguished by the presence of the fungi Debaryomyces hansenii and Candida spp. , whereas Mytilini sausages by the bacteria Lactococcus and Streptococcus . Traditionally produced sausages from the Pitsilia region of Cyprus were differentiated by the presence of the species Lactobacillus helveticus , whereas industrially produced sausages were differentiated by the species Leuconostoc mesenteroides . Focusing mainly on Lactobacillus and Leuconostoc , negative associations with pathogenic bacteria, such as Salmonella , and spoilage fungi, such as Fusarium poae , were revealed.
Conclusion: The present metataxonomic analysis provided insights into the microbial communities that characterize Cypriot and Mytilini sausages. The findings provide an indication that the microbial diversity might be applied as an additional marker of Cypriot sausages’ authenticity.
Emissions leakage and economic losses could limit the effectiveness of deforestation-linked oil crop import restrictions
Authors: Yarlagadda Brinda , Zhao Xin , Iyer Gokul , Wild Thomas , Hultman Nathan , Lamontagne Jonathan 
Published: October 2024

Abstract

Import restrictions on deforestation-linked commodities have been enacted, aiming to reduce global deforestation and emissions. However, limited market share held by importers imposing such restrictions and the potential for emissions leakage could reduce their effectiveness. Moreover, they could result in negative economic implications for producers and consumers. We quantify future emissions and economic implications of oil palm and soybean import restrictions. Current EU restrictions will likely have minimal impact due to the EU’s otherwise small and diminishing share of global palm and soy demand. If extended beyond the EU, import restrictions could drive reductions in cumulative land-use change (LUC) emissions by 2050 in key oil crop exporting regions— up to 1.6% in Indonesia, 2.1% in the rest of Southeast Asia, 4.6% in Argentina and 8.3% in Brazil relative to a scenario with no restrictions. However, globally, directly protecting forest land could be more effective than indirectly via import restrictions, due to emissions leakage. Meanwhile, import restrictions could result in key exporters facing losses of $0.1-$280 billion in cumulative agricultural production revenue by 2050. Broadly, our study highlights that the effectiveness of import restriction policies in reducing emissions globally will rely on coordinated action across major oil-crop producing and consuming regions.
Synthesis of a novel CuO@GO@IR nanocomposite for the removal of tetracycline from wastewater
Authors: Sharma Anchal , Garg Vinod Kumar 
Published: October 2024

Abstract

Antibiotics are a pressing concern because of their extensive use in human and veterinary medicines. In this study, removal of tetracycline (TC), a common antibiotic, from aqueous solutions has been investigated. The water extract of Indian rosewood tree leaves has been used to synthesize copper oxide nanoparticles (CuO NPs) further loaded on graphene oxide sheets to synthesize a nanocomposite (CuO@GO@IR). The removal efficiency of this nanocomposite was evaluated under varying process conditions, viz., pH, adsorbent dosage, initial TC concentration, contact time, and temperature, using batch mode. The maximum tetracycline removal was at pH 3, 0.03 g/50mL adsorbent dose, and 240 min. contact time. The experimental data were better fitted to the Freundlich isotherm, indicating heterogeneous adsorption, with a maximum adsorption capacity of 769.23 mg/g. The adsorption process followed pseudo-second-order kinetics, and the thermodynamic parameters indicated that the adsorption process was spontaneous and feasible. The reusability of the nanocomposite was explored using ethanol, 0.1M HCl, 0.1 NaOH as desorbing agents. These results suggest that the CuO@GO@IR nanocomposite can be used for tetracycline removal from aqueous medium.