bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH SHOPPING EXPERIENCE TERHADAP BRAND IMAGE KAWASAN OBJEK WISATA BELANJA BATIK TRUSMI (Survei terhadap Pengunjung Kawasan Objek Wisata Belanja Batik Trusmi Kabupaten Cirebon)
Authors: Novianti Ranny Achni , Purnama Ridwan 
Published: May 2019

Kabupaten Cirebon is one of regencies in West java has tourism potential can be relied, and the one of destination is Kawasan Objek Wisata Belanja Batik Trusmi. Kawasan Objek Wisata Belanja Batik Trusmi is a shopping tourism area that offers a variety oftypicalCirebonanbatikcollection. The number of tourist visits on Kawasan Objek Wisata Belanja Batik Trusmi has decreased from 2007 to 2010. The most drastic decrease of tourist visit happened in 2010. Shopping experience is one of marketing strategy that can be used to increase the number of visit. In connection with these to research studies conducted on the influence shopping experience toward brand image Kawasan Objek Wisata Belanja Batik Trusmi. The purpose of this research is to find shopping experience influence brand image to Kawasan Objek Wisata belanja Batik Trusmi. Promotion mix consists of price, characteristics ofdestinations, merchandising, authenticity, and staff service quality. Technique of sampling is simple random sampling.The method in that used in this research is explanatory survey by using ordinal scale.Analyze from this research use Path Analysis with a computer software tools SPSS 19.0. The result of this research is shopping experience influence significantly 71,48% and the rest influence other factors. Based on the result of statistical test results were obtained, there were three variables of shopping experience which had an influence on brand image of price, merchandising, and authenticity and there was two variables that had no effect on brand image was characteristics ofdestinations and staff service quality.That it can be concluded that price, merchandising, and authenticity strong influence brand image on Kawasan Objek Wisata Belanja Batik Trusmi.
Evaluation of short term outcome on distal femoral fractures using distal femoral nail: revisiting the technique
Authors: Kalia Sandeep , Sharma Shalini 
Published: May 2019

<p class="abstract"><strong>Background:</strong> Distal femoral fractures account for 6 to 7% of all femur fractures. Ideal treatment of these fractures demands indirect reduction as well as stable fixation by implant which could tolerate the stress and strain forces till healing of fracture. Distal femoral nailing fullfils these demands.</p><p class="abstract"><strong>Methods:</strong> Fifteen patients with seventeen fractures were treated by this method as a prospective study at the tertiary care institute in north india. Patients were evaluated post operatively with average follow up duration of 45.59±15.99 weeks.<strong></strong></p><p class="abstract"><strong>Results:</strong> 88% of the patients were having associated trauma. Male/female ratio was 9/8. Mean delay in surgery was 21.86±23.85 days (1-64 days). Reduction was satisfactory in all patients. Average hospital stay was 18.71±8.23 days (6-34 days). Clinical union was seen in 16 out of 17 fractures by the end of six months with average period of 4.19±0.83 months. Radiological union lagged behind clinical union with average of 5.14±0.44 months. Post operatively 5 patients with delayed union needed dynamization, 2 needed bone grafting . One case of non union was seen. There were two cases of infection requiring debridement. Average knee flexion was 90.35±22.95degree (50-130 degree). Average extension lag was 3.88±2.88 degree (0-10 degree). Sanders function evaluation scale at final follow up showed 11.8% excellent, 47.2% good, 23.6% fair and 17.6% poor result.</p><p class="abstract"><strong>Conclusions:</strong> Distal femoral nailing has good results in distal femur fracture as the fixation is more biological and stable allowing early healing and better outcome</p>
Louise Colet et l'Italie des Italiens : le récit de voyage d’une vieille romantique
Authors: Poyet Thierry 
Published: May 2019

Habituée des récits de voyage, Louise Colet révèle avec L’Italie des Italiens une sensibilité politique très progressiste : en s’emparant du Risorgimento, l’écrivaine se rêve en conscience politique. À la fois témoin et figure de l’intellectuel avant l’heure, elle développe cependant de nombreux partis pris qui attestent une culture romantique bien vivace. Le prétendu guide de voyage prend alors une dimension idéologique plus ou moins assumée tout en se teintant des couleurs vives du discours autobiographique. Œuvre foisonnante et complexe, L’Italie des Italiens s’impose comme un objet littéraire tout à fait singulier dans la production du XIXe siècle. Accustomed to travel stories, Louise Colet reveals with L’Italie des Italiens a very progressive political sensibility: in the spirit of the Risorgimento, the writer is dreaming in political conscious­ness. At the same time witness and figure of the intellectual before the hour, she develops however many biases which attest a very lively romantic culture. The so-called travel guide takes on a more or less assumed ideological dimension while tinting the bright colors of the autobiographical discourse. A prolific and complex work, L’Italie des Italiens stands out as a literary object quite singular in the literary production of the nineteenth century.
Modelos ajustados para biomasa de culmos de guadus (Guadua angustifolia Kunth) individuales en rodales manejados en el su de Costa Rica
Authors: Briceño-Elizondo Elemer 
Published: May 2019

Este estudio tiene como objetivo ajustar datos de campo a modelos no lineares con el fin de predecir el crecimiento y estimar la acumulación de biomasa en plantaciones de bambú bajo manejo en sitios productivos. La plantación está ubicada cerca de la comunidad de Rio Claro en el distrito de Guaycará, Cantón de Golfito, Provincia de Puntarenas, Costa Rica. Cinco rodales fueron identificados para el estudio, con tres de ellos utilizados para la calibración y dos para la validación de modelos. Una estratificación por cohorte de altura fue necesaria para organizar la base de datos a un mejor ajuste; a saber H1: 0 a 4 m., H2: 4,01 a 7 m., H3: 7,01 a 10 m., H4: superior a 10,01 m. Los datos de inventario se ajustaron mediante regresión no lineal a tres modelos de biomasa seleccionados utilizados en estudios anteriores de biomasa de bambú. Las variables predictivas utilizadas fueron diámetro, altura y área basal.
La calidad de la predicción del modelo se probó mediante la prueba de Wilcoxon para muestras pareadas; la biomasa empírica de la base de datos usada en validación se emparejó a las predicciones modelo de los tres modelos. Las predicciones de los modelos Bm1, Bm2 y Bm3 no son significativamente diferentes de los datos empíricos (p = 0.7064, 0.7735 0.8822 respectivamente). Sólo Bm1 tiende a sobrestimar, pero el rango es aceptable para la predicción. Los resultados promedio obtenidos aquí son 12,49, 12,82 y 12,9 Mg ha-1 de biomasa en los modelos Bm1, Bm2 y Bm3 respectivamente, son mayores a los encontrados por otros autores en bosques de bambú Moso en el sur de China donde encontraron 8,13 ± 2,15 Mg ha-1 Año-1. Aunque la comparación es con otra especie y la edad máxima es diferente de la plantación (5 años en Moso en comparación con 3 años) se puede sugerir que, al igual que en árboles, se espera un rango de biomasa según edad, manejo y dimensiones.
Gestión y manejo de las aguas residuales no domésticas en la ciudad turística de La Libertad, El Salvador. Desafíos para alcanzar un desarrollo sostenible
Authors: Rosales-Ayala Francisco , Campos-Rodríguez Rooel 
Published: May 2019

Esta investigación tuvo como objetivo caracterizar la gestión municipal de las aguas residuales no domésticas, generadas por el sector comercial y de servicios de la ciudad de La Libertad en El Salvador; lo que permitió identificar los desafíos para alcanzar un desarrollo sostenible.
Para desarrollar esta investigación se consultaron fuentes secundarias y se realizaron entrevistas semiestructuradas al personal técnico, y político de la Alcaldía Municipal.
La ciudad de La Libertad es emblemática del turismo nacional costero; sin embargo, presenta serios problemas ambientales: el 28% de los negocios son generadores de aguas residuales no domésticas; el sistema de alcantarillado es obsoleto, con una cobertura del 61,7%; mientas que la planta de tratamiento municipal se encuentra en malas condiciones, con una eficiencia depurativa del 50%. Fruto de la mala gestión de las aguas residuales y de los residuos sólidos, se producen colapsos tanto en el sistema de alcantarillado como de las aguas lluvias de la ciudad.
Todo esto genera deterioro en la imagen de la ciudad, mayor insalubridad, contaminación de ríos, quebradas y playas; dificultando el desarrollo turístico sostenible. Aunque la municipalidad tiene conciencia de la problemática, por el momento no cuenta con estrategias e instrumentos necesarios para hacer una gestión integral de las aguas residuales.
El ordenamiento territorial, la mejora de equipamiento e infraestructura sanitaria, la educación ambiental y el fortalecimiento de las capacidades locales para la aplicación de la legislación ambiental municipal, son desafíos claros para lograr el desarrollo sostenible de la ciudad.
Evaluation of the Chelating Efficacy of Aquilaria malaccensis and Aristolochia longa Against Biochemical Alterations Induced by Lead Bioaccumulation in Rats
Authors: Derouiche Samir  , Zeghib Khaoula  
Published: May 2019

The current study was evaluated the chelating effect of Aquilaria malaccensis and Aristolochia longa against lead induced biochemical alterations and bioaccumulation of lead in tissues of rats. 25 adult female Wistar albino rats, equally divided into control and four treated groups, received either lead, lead + A. malaccensis, lead + A. longa and lead + A. malaccensis + A. longa lead (100 mg/kg b.w) as Pb(C2H3O2)2 added in their drinking water for 75 days. A. malaccensis and A. longa (at a dose 1% of diet) were added to the feed during the last 15 days of lead exposed in the animals. Result showed that in lead-intoxicated rats, an increase of lead accumulation in serum, bone and liver of rats. Results also revealed that lead affected metabolic system by increasing blood glucose and serum urea concentrations and decreasing serum calcium concentration. Treatment with A. malaccensis and A. longa alone or combined significantly reduced the adverse effects related to most of serum and tissue lead accumulation and restored biochemical parameters alterations in animals treated with lead. The present study shows that A. malaccensis and A. longa are an effective chelating agents for the removal of lead and it has proved efficient in restoring both the biochemical alteration and toxicity after a sub lethal exposure of lead acetate in rats.
Análisis de accesibilidad universal de las plazas del centro histórico de Madrid = Universal Accessibility Analysis of Madrid Downtown Squares
Authors: Chacón Martínez Katherine M. 
Published: May 2019

ResumenDurante los últimos 20 años, el desarrollo del paradigma de “diseño urbano inclusivo” ha presentado nuevos retos en la planificación urbana frente a la implementación del componente de accesibilidad universal. Ante ello, Ecuador y España han trabajado en la construcción de legislaciones específicas, normativas, ordenanzas y herramientas técnicas que han dado paso al establecimiento de parámetros de obligatorio cumplimiento en todos los espacios, más aún en lugares de cohesión social como plazas, calles y parques. Al respecto, la presente investigación se enmarca en el análisis de accesibilidad universal de las plazas del Centro Histórico madrileño a fin de identificar los niveles de esta condición y reconocer si se está cumpliendo con los requisitos mínimos o atendiendo a las diferentes tipologías de discapacidad existentes. Tras realizar un estudio normativo que denota las similitudes en parámetros técnicos entre las legislaciones de Ecuador y España, se recurrió a la “Metodología Ecuatoriana para la Elaboración de Planes de Accesibilidad Universal” basada en la normativa ISO 21542 de “Accesibilidad al Entorno Construido” para la evaluación de los espacios. Considerando los resultados obtenidos se establece que existen fallas en el diseño que pueden ser corregidas con el objeto de generar una ciudad más inclusiva.AbstractDuring the last 20 years, the development of the "Inclusive Urban Design" paradigm has presented new challenges in urban planning in regard to the implementation of the universal accessibility component. In response, Ecuador and Spain have worked on the construction of specific legislation, regulations, policies and technical tools that have led to the establishment of mandatory parameters in all spaces, especially in places of social cohesion such as squares, streets and parks. In this regard, this research is framed in the analysis of universal accessibility of the Madrid Downtown Squares in order to identify the levels of this condition and recognize that the fulfillment is based on the minimum requirements or attending the different typologies of the existing disability. After carrying out a normative study that shows the similarities in technical parameters between the legislations of Ecuador and Spain, the "Ecuadorian Methodology for the Elaboration of Universal Accessibility Plans" based on the ISO 21542 standard of "Accessibility to the Built Environment" for the evaluation of the spaces was used. Considering the results of the study, there are flaws in the design which can be improved in order to generate a more inclusivecity.
Elastisitas Penawaran Output dan Permintaan Input Usahatani Bawang Merah di Kabupaten Demak, Jawa Tengah (Elasticity of Output Supply and Input Demand of Shallot Farming in Demak District, Central Java)
Authors: Sahara Dewi , Chanifah NFN 
Published: May 2019

<p>Bawang merah merupakan salah satu komoditas sayuran yang mempunyai peran strategis bagi perekonomian Indonesia. Untuk meningkatkan produksi bawang merah, petani menggunakan beberapa input produksi. Perubahan harga bawang merah akan berdampak pada penawaran output dan permintaan input. Penelitian bertujuan untuk mengetahui pengaruh perubahan harga output dan harga input terhadap penawaran output dan permintaan input usahatani bawang merah di Kabupaten Demak, Jawa Tengah. Penelitian dilaksanakan di Desa Raji, Kecamatan Demak, Kabupaten Demak pada bulan September – Desember 2016. Penelitian menggunakan data primer yang dikumpulkan melalui metode survey terhadap 30 responden. Data dianalisis dalam bentuk pangsa permintaan input dengan metode Seemingly Unrelated Regression (SUR). Hasil penelitian menunjukkan bahwa penawaran bawang merah elastis terhadap perubahan harga bawang merah dan harga umbi benih, namun kurang elastis terhadap perubahan upah tenaga kerja, serta tidak elastis terhadap perubahan harga pupuk. Permintaan input (umbi benih, pupuk, dan tenaga kerja) bersifat elastis terhadap harga masing-masing input tersebut, dan sebagian besar bersifat inelastis terhadap harga input lainnya. Oleh karena itu untuk meningkatkan penawaran bawang merah, pemerintah seyogyanya mampu menjaga stabilisasi harga bawang merah dan mendorong menggunakan biji bawang merah (true seed shallot) sebagai alternatif untuk mengurangi pemakaian benih umbi bawang merah.</p><p><strong>Keywords</strong></p><p>Bawang merah; Perubahan harga; Penawaran output; Permintaan input</p><p><strong>Abstract</strong></p><p>Shallot is one of the vegetable crops that have a strategic role for the Indonesian economy. To increase the production of shallot, the farmers using several of input production. Changes of shallot would have an impact to output supply and input demand. This study aimed to determine the effect of changes in input and output prices to output supply and input demand of shallot farming. The study was conducted in Raji Village, Demak Subdistrict, Demak District in September - December 2016. Primary data was collected through survey method by interviewing 30 respondents. The data was analyzed in the form of input demand share by Seemingly Unrelated Regression (SUR) method. The results showed that supply of shallot is elastic to the price changes of shallot and price of seed bulbs, but less elastic to changes in labor wages and inelastic to changes in fertilizer prices. Demand for production input is elastic to the price of each input, and are largely inelastic with respect to other input prices. Therefore, to increase the shallot supply, the Government should be able to maintain the stabilization of shallot prices and encourage the use of true seed shallot as an alternative to reduce the use of shallot seeds.</p>
Analisa Rantai Pasok Komoditas Tembakau Madura
Authors: Umam Faikul 
Published: May 2019

<p><strong>ABSTRAK</strong></p><p><em>Komoditas tembakau Madura merupakan salah satu komoditas perkebunan yang yang banyak dibudidayakan oleh petani Madura. Akan tetapi pada kenyataannya, petani tembakau madura masih belum bisa menjual tembakaunya dengan harga yang tinggi. Ini dikarenakan panjangnya rantai pasok penjualan tembakau Madura. Terdapat beberapa interrmediate trader dalam rantai pasok tersebut dan setiap intermediate trader juga mengambil keuntungan penjualan. Penelitian ini bertujuan untuk memperbaiki mekanisme rantai pasok penjualan tembakau Madura. Metode yang digunakan pada penelitian ini yaitu analisa SWOT dan analisa rantai pasok. Data diperoleh dengan melakukan FGD dan wawancara. Hasil penelitian berupa rekayasa rantai pasok penjualan komoditas tembakau dengan menciptakan marketplace. Diharapkan penelitian ini bisa menjadi input bagi penelitian selanjutnya dalam proses desain dan membangun marketplace.</em></p><p><em>Kata Kunci: </em><em>tembakau madura, SWOT, rantai pasok, marketplace </em><em></em></p><p align="center">SUPPLY CHAIN ANALYSIS OF MADURA TOBACCO COMMODITIES</p><p><strong> </strong></p><p><strong>ABSTRACT</strong></p><p><em>Product of Madura tobacco is one of the plantation commodities which is widely cultivated by Madurese farmers. In fact, though Madura tobacco farmers still could not sell their tobacco at a higher price. This is due to the supply chain of Madura tobacco sales which has a long network. There are several intermediate traders in the supply chain network and each intermediate trader takes sales profits as well. This research aims to analyze and remodel the supply chain mechanism for Madura tobacco sales. This study employed a SWOT analysis and supply chain analysis. Data were obtained by conducting FGDs and interviews. The research results from a new model of the sales supply chain for Madura tobacco by creating a marketplace. It is expected that this work can be useful as an input for further study in designing and building a marketplace</em>.</p><em>Keywords: Madura tobacco, SWOT, supply chain, marketplace</em>
Gene expression profile of human T cells following a single stimulation of peripheral blood mononuclear cells with anti-CD3 antibodies
Authors: Sousa Isabel Garcia , Simi Kelly Cristina Rodrigues , Almo Manuela Maragno do , Bezerra Maryani Andressa Gomes , Doose Gero , Raiol Taina , Stadler Peter F , Hoffmann Steve , Maranhão Andrea Queiroz , Brigido Marcelo M 
Published: May 2019

Abstract
Background: Anti-CD3 immunotherapy was initially approved for clinical use for renal transplantation rejection prevention. Subsequently, new generations of anti-CD3 antibodies have entered clinical trials for a broader spectrum of therapeutic applications, including cancer and autoimmune diseases. Despite their extensive use, little is known about the exact mechanism of these molecules, except that they are able to activate T cells, inducing an overall immunoregulatory and tolerogenic behavior. To better understand the effects of anti-CD3 antibodies on human T cells, PBMCs were stimulated, and then, we performed RNA-seq assays of enriched T cells to assess changes in their gene expression profiles. In this study, three different anti-CD3 antibodies were used for the stimulation: two recombinant antibody fragments, namely, a humanized and a chimeric FvFc molecule, and the prototype mouse mAb OKT3.
Results: Gene Ontology categories and individual immunoregulatory markers were compared, suggesting a similarity in modulated gene sets, mainly those for immunoregulatory and inflammatory terms. Upregulation of interleukin receptors, such as IL2RA, IL1R, IL12RB2, IL18R1, IL21R and IL23R, and of inhibitory molecules, such as FOXP3, CTLA4, TNFRSF18, LAG3 and PDCD1, were also observed, suggesting an inhibitory and exhausted phenotype.
Conclusions: In conclusion, we used a deep transcriptome sequencing method for comparing three anti-CD3 antibodies in terms of Gene Ontology enrichment and immunological marker expression. The present data showed that both recombinant antibodies induced a compatible expression profile, suggesting that they might be candidates for a closer evaluation with respect to their therapeutic value. Moreover, the proposed methodology is amenable to be more generally applied for molecular comparison of cell receptor dependent antibody therapy.
Assessment of the performance of orthopaedic residents in clinical practice
Authors: Silva Bruno Machado , Rassi Marcos , Pereira Edna 
Published: May 2019

Abstract
Objective

Mini-Clinical Evaluation Exercise (Mini-CEX) is a strategy for performing and documenting direct observation and formative assessment of clinical skills. This assessment method promotes identify deficiencies in history taking, physical examination and counseling skills. Furthermore, Mini-CEX is easy to implement and less cost. Thus, our objective was to evaluate the performance of orthopaedic residents in while conducting clinical examinations.

Methods

Mini-CEX was applied by three faculties in four different moments. The instrument was adapted by the authors for use in orthopaedics, with the development of descriptors for each evaluated skill. Supervisors were trained to use the Mini-CEX by the principal investigator through teaching materials and discussions, with standardization of the instrument descriptors.

Results

The mean scores obtained in the 4 evaluations for each of the 21 residents reveal improvement in the performances of residents in all skills assessed from the first to the fourth meeting.

Conclusions

We have found that the performance of orthopaedic residents presented a satisfactory evolution, with progressive improvement in all skills.