bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing and enhancing the circularity and sustainability of emergency hospital shelters
Authors: Hendriks Eefje , de Zwart Joop , Compeer Alexander , Gospodinova Julia 
Published: December 2024

AbstractLeading humanitarian organisations strive to enhance the sustainability of their aid to avoid negative impacts on the environment, economy, and society, particularly in low‐resource areas. This study explores how the circularity and sustainability of emergency hospital shelters can be assessed using literature, expert interviews, co‐creation and design sessions, and pilot testing. The approach combines a qualitative circularity checklist with a quantitative environmental impact assessment, providing valuable input for informed decision‐making during procurement and design. The findings reveal that existing buildings are commonly repurposed before importing emergency hospital shelters—finite virgin materials are primarily used for the production of new shelters—and there is a lack of data with which to reflect on end‐of‐life scenarios. The study recommends enhanced monitoring of the shelter lifecycle through data collection as an input for continuous improvement procedures of design and supply. Crucial are extended stakeholder responsibilities for the entire lifecycle and sector‐wide adoption of circularity and sustainability ambitions, mainstreaming approaches and showcasing benefits.
Evolutionary Genomics Provides Insights Into Endangerment and Conservation of a Wild Apple Tree Species, Malus sieversii
Authors: Zhang Jian , Zhao Fang‐Yuan , Zhang Hong‐Xiang 
Published: December 2024

ABSTRACTUnderstanding the evolutionary history of a species is essential for effective conservation management. Malus sieversii, a relict broad‐leaf forest tree found in arid Central Asian mountains, has a narrow and fragmented distribution and is classified as an endangered species in China. This species is considered one of the ancestors of the domesticated apple trees. In the present study, we sampled five populations of M. sieversii and its wide‐ranging congener M. baccata from China. Through deep whole‐genome resequencing, we analyzed the population's genetic diversity, genetic structure, demographic history, fixation of deleterious mutations, and genomic divergence. Our results revealed that M. baccata exhibits a higher level of genetic diversity than M. sieversii. The effective population size of M. sieversii decreased, whereas that of M. baccata recovered after the bottleneck effect. In M. sieversii, the genetic structure of the Yili region was distinct from that of the Tacheng region. Populations at the rear edge of the Tacheng region showed a stronger fixation of deleterious mutations than those in the Yili region. Genomic divergence indicated that the positively selected genes were associated with physiological processes within the genomic islands between the Yili and Tacheng regions. Based on these findings, we recommend the establishment of two separate conservation units for the Yili and Tacheng lineages to preserve their genetic resources. Given the limited distribution range and high fixation rate of deleterious mutations, urgent protective measures are recommended for the Tacheng lineage.
The Scientific Achievements of Gordon H. Copp (1956–2023): An Unabridged Version From His Doctor of Science Portfolio
Authors: Vilizzi Lorenzo , Tricarico Elena 
Published: December 2024

ABSTRACTThis paper outlines the scientific achievements of Gordon H. Copp (1956–2023) in fish biology and invasion science as presented in his Doctor of Science portfolio. Gordon's mentorship began during his postdoctoral research and expanded to involve students, early‐career researchers as well as prominent fish biologists in a vast number of research projects. Early in his career, Gordon was involved in the study of floodplain fish communities for which he developed a novel technique for sampling young‐of‐year (0+) fish and in the early ontogeny of fishes. Gordon's later involvement in non‐native species policy has been pivotal, from developing risk analysis schemes for freshwater fishes to advising on EU and UK regulations. Gordon's research throughout his entire career on the pumpkinseed sunfish Lepomis gibbosus as a model species highlights his focus on understanding and predicting invasiveness under varying climate conditions, contributing to a broader understanding of non‐native species impacts.
Effects of Recreational Fishing Gear Type on Reflex Impairment and Post‐Release Swimming Activity of Smallmouth Bass
Authors: LaRochelle Luc , Bernardi Joseph , Madden Jamie C. , Brownscombe Jacob W. , Goodenough Alyssa M. , Danylchuk Andy J. , Cooke Steven J. 
Published: December 2024

ABSTRACTRecreational anglers have access to a diverse range of rod and line strengths that enable them to choose equipment that can enhance their ability to effectively target and capture specific fish of a given body size. However, anglers may not always select the appropriate gear type for the targeted species. Here, we assessed the effect of gear setup on immediate reflex impairment and short‐term post‐release swimming behavior of Smallmouth Bass (Micropterus dolomieu) for 10‐min. Smallmouth Bass were caught by angling in water temperatures of 22.7°C–26.2°C using ultralight or medium spinning gear. Fight times were longer for fish captured on ultralight gear than medium gear, and fight times were longer for larger fish. Generally, fight times > 18 s resulted in one or more immediate reflex impairments, while fish with fight times < 18 s had no immediate reflex impairments. Post‐release swimming activity was only influenced by gear type used. Upon release, Smallmouth Bass captured using ultralight gear spent more time sustained swimming than those caught using medium gear type that spent more time resting. Given that fight times were longer for Smallmouth Bass captured using ultralight gear, they were conceivably more exhausted. This increased post‐release swimming activity indicates that fish may need to engage in sustained swimming to facilitate physiological recovery. Our findings suggest that anglers should select gear types that minimize fight times to avoid reflex impairments and extended periods of post‐release sustained swimming needed for recovery.
Effect of Macrolide Exposure on Tailored Helicobacter pylori Eradication Therapy and Antibiotic Resistance Profiles: A Prospective Study Using the Drug Utilization Review System
Authors: Noh Jin Hee , Choi Kee Don , Na Hee Kyong , Ahn Ji Yong , Lee Jeong Hoon , Jung Kee Wook , Kim Do Hoon , Song Ho June , Lee Gin Hyug , Jung Hwoon‐Yong 
Published: December 2024

ABSTRACTBackground/AimsDetermining antibiotic use history accurately is challenging due to its reliance on patient recall. By determining macrolide exposure using the Korean drug utilization review (DUR) system, we analyzed the impact of previous macrolide use on antibiotic resistance profiles and compared the eradication rate between tailored therapy based on macrolide exposure history and empirical therapy.MethodsPatients with confirmed Helicobacter pylori (H. pylori) infection who agreed to access prescription information using the Health Insurance Review and Assessment Service DUR system were enrolled between 2021 and 2023. Patients received tailored therapy, which was clarithromycin (CLR)‐based triple therapy in cases without macrolide exposure and bismuth quadruple (BQ) therapy in cases with macrolide exposure. The empirical therapy group was prospectively recruited at the same time to compare the eradication rate.ResultsA total of 418 patients (tailored therapy group, n = 57; empirical therapy group, n = 361) were analyzed. Among the tailored therapy group, 24.6% took macrolide antibiotics for the past 5 years. CLR resistance rates were higher in patients with previous macrolide use than in those without (66.7% vs. 7.5%, p < 0.001). The tailored therapy group showed a higher eradication rate than the empirical therapy group for intention‐to‐treat (ITT), modified intention‐to‐treat (MITT), and per‐protocol (PP) analyses (ITT, 86.0% vs. 75.6%; MITT, 94.2% vs. 80.3%; PP, 94.2% vs. 85.1%).ConclusionsPrevious macrolide exposure identified using the DUR system was associated with a higher rate of CLR resistance. Tailored therapy based on macrolide exposure history led to higher eradication rates compared to empirical therapy.
8‐T Framework for Artificial Intelligence‐Driven Branding: A Strategic Typology
Authors: Deryl Maria DSouza , Verma Sanjeev , Srivastava Vartika 
Published: December 2024

ABSTRACTThe marketing ecosystem is experiencing a paradigmatic shift with the advent of artificial intelligence (AI). The present study aims to widen the foundations of brand strategy by integrating AI dimensions within the branding dominion. The literature lacks a cohesive perspective on AI dimensions boosting and driving brands for sustained competitive advantage in the dynamic marketplace. Marketing practitioners are gradually getting acquainted with the nuances of AI implementation, but latent AI capabilities remain potent to unfurl enduring consumer relationships. The present study develops a novel 8‐T Strategic Framework for facilitating the strategic integration and effective implementation of AI in brand decisions and initiatives. The theorization of the 8‐T framework of AI‐driven branding (Technology, Training, Teaming, Targeting, Technique, Timing, Tailoring, Trust) offers macro and micro perspectives that serve as a formidable typology. The framework enunciates a holistic set of strategic mechanisms to help practitioners build futuristic strategies with a contemporary purpose.
Mandatory Data Breach Disclosure and Insider Trading
Authors: Chen Xi , Hilary Gilles , Tian Xiaoli 
Published: December 2024

ABSTRACTWe examine whether mandatory data breach disclosure affects insider‐selling behavior and find that selling profits are greater after states require firms to disclose data breaches. The effect is more pronounced for firms with weaker corporate governance, higher cybersecurity risk, and without prior investment in material cyber protection programs. However, insiders profit less when they operate in states with stricter laws and face higher litigation risks. The evidence is consistent with managers personally hedging risks in the capital market when mandatory disclosure laws designed to protect customers are weakly enforced. Laws designed to improve transparency in the product markets may have the unintended effect of reducing the integrity of financial markets. However, insider sales also facilitate the incorporation of bad news in stock prices, making idiosyncratic crashes less likely.
Phylogenetic Diversity of Live‐Bearing Fishes (Poeciliidae) Peaks on Peninsulas, Isthmuses, and in Deserts
Authors: Gómez‐Martínez Roni Fernando , Matamoros Wilfredo A. , Hoagstrom Christopher W. , López‐Vila Jesús Manuel , Bonilla Esteban Pineda Diez de 
Published: December 2024

ABSTRACTAimPoeciliids are ecologically important, are widely used as pets, and also have value as model organisms. To understand diversity within this family, we study their phylogenetic diversity (PD) at regional and local scales to delimit bioregions and identify patterns of biodiversity.LocationThe Americas.TaxonPoeciliidae (Actinopterygii: Cyprinodontiformes).MethodsWe expanded an existing dated phylogeny from 164 to 261 species with distributional data for 1o × 1o latitude × longitude cells (~111 km2) and conducted a cluster analysis (phylo‐jaccard distance) to delineate bioregions. For individual cells, we mapped species richness (SR), phylogenetic diversity (PD), weighted endemism (WE) and phylogenetic endemism (PE). We used randomisation tests to map phylogenetic clustering and over‐representation of short‐branch species by cell. We used categorical analysis of neo‐ and palaeo‐endemism to map neo‐, palaeo‐, mixed and super (mixed) endemism.ResultsWe delineated six bioregions. Highest regional species density and density of PD occurred on the Isthmus of Panamá (IOP). At the grid‐cell scale, the Grijalva–Usumacinta drainage is a hotspot for SR, PD, PE and WE; the IOP has high PD and PE; the Isthmus of Tehuantepec (IOT) has high PD, WE and moderately high SR; and western Hispaniola has high WE and moderately high SR. The Grijalva–Usumacinta drainage also includes cells of super (mixed) and palaeoendemism, while mixed endemism is widespread in Middle America and the Greater Antilles. Phylogenetic clustering is widespread, whereas over‐representation of short‐branch species is concentrated in the Chihuahuan Desert–Sierra Madre Oriental region and in western Hispaniola, both hotspots of neoendemism.Main ConclusionsWe found widespread diversification of genera intermixed with relict species (mixed endemism). Furthermore, SR and PD were strongly correlated. Centres of endemism include the Chihuahuan Desert–Sierra Madre Oriental, western Hispaniola, the IOT, the IOP and (most of all) the Grijalva–Usumacinta drainage. However, conservation efforts must occur within each bioregion and for each genus.
Development of Technology for Producing Combined Meat Chips With Reduced Sodium Content
Authors: Kaisarova Arailym , Shingisov Azret , Mukhametov Almas , Kenenbay Shynar 
Published: December 2024

ABSTRACTHigh sodium intake from processed foods has been linked to increased risks of hypertension and cardiovascular diseases, prompting the need for sodium reduction strategies in meat products. This study aims to investigate the influence of partially replacing salt (NaCl) with Salicornia herbacea L. in the formulation of meat chips on their yield, quality, and sensory characteristics. The main difference between control and experimental recipes lies in the substitution of part of the salt (NaCl) with S. herbacea L., known for its beneficial properties and lower sodium content. Beef, chicken breast, and horse meat were used for chip preparation. Control recipes contained 8% NaCl, whereas in experimental recipes, NaCl constituted 4%, and S. herbacea L. constituted 4%. The preparation process involved grinding the meat to a minced state, adding salt and spices, forming chips, a three‐stage drying process, and subsequent cooling. The results indicated that the inclusion of S. herbacea L. reduces chip yield by 2%. Moisture, fat content, protein composition, and caloric content of the chips also slightly decreased in experimental recipes. Meanwhile, antioxidant activity and chip‐shape stability increased. Experimental recipes also demonstrated improved sensory characteristics such as taste, aroma, and texture. Thus, despite a minor decrease in production yield the use of S. herbacea L. in meat chip formulations was justified. Simultaneously, alongside sodium reduction, there was an improvement in the product's antioxidant activity and sensory properties. The incorporation of S. herbacea L. makes meat chips more nutritious and appealing to health‐conscious consumers.
Effect of Different Types of Antithrombotic Agents on Clinical Outcomes in Patients With Small Bowel Bleeding Who Underwent Balloon‐Assisted Enteroscopy: A KASID Multicenter Study
Authors: Park Jihye , Kim Jin Su , Song Joo Hye , Nam Kwangwoo , Kim Seong‐Eun , Jeong Eui Sun , Kim Jae Hyun , Jeon Seong Ran ,   The Small Intestine Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)
Published: December 2024

ABSTRACTBackground and AimThe impact of different anti‐thrombotic agents on patients with suspected small bowel bleeding (SSBB) who underwent balloon‐assisted enteroscopy (DAE) is unclear. We aimed to examine the clinical effects and predictive factors of DAE based on the thromboembolic agents used.MethodsWe enrolled 399 patients with SSBB from a web‐based DAE registry across 30 medical centers in South Korea. Among them, 291 patients did not receive anti‐thrombotic agents, whereas 80, 22, and 6 patients received anti‐platelet agents, direct oral anti‐coagulants (DOACs), and warfarin, respectively.ResultsDiagnostic yields were similar across groups; however, therapeutic yields differed: 25.4%, 37.5%, 63.6%, and 83.3% in patients treated with no anti‐thrombotic agents, anti‐platelets, DOACs, and warfarin, respectively (p < 0.001). The multivariable logistic regression revealed that patients treated with DOACs and warfarin experienced significantly higher therapeutic yields (odds ratio [OR]: 2.803 and 9.526, respectively; 95% confidence interval [CI]: 1.048–7.500 and 1.061–85.481, respectively; p = 0.040 and 0.044, respectively) than those treated with no anti‐thrombotic agents. The re‐bleeding rates in patients treated with no anti‐thrombotic agents, anti‐platelets, DOACs, and warfarin were 9.6%, 6.3%, 13.6%, and 50.0%, respectively (p = 0.069). In the multivariable logistic regression analysis, patients treated with warfarin exhibited higher re‐bleeding rates than those not treated with anti‐thrombotic agents (OR: 9.393, 95% CI: 1.809–48.764, p = 0.008).ConclusionsThe diagnostic yield of DAE did not differ based on the anti‐thrombotic agent type, whereas the therapeutic yield of DAE in DOAC and warfarin users was high. Careful monitoring for re‐bleeding is advised in DOAC as well as warfarin users.
An online driving decision aid for older drivers reduces ambivalence and regret about driving decisions: Randomized trial
Authors: DiGuiseppi Carolyn G. , Hill Linda L. , Fowler Nicole R. , Johnson Rachel L. , Peterson Ryan A. , Han S. Duke , Josewski Brandon , Knoepke Christopher E. , Matlock Daniel D. , Omeragic Faris , Betz Marian E. 
Published: December 2024

AbstractBackgroundDecisions about driving cessation can be stressful for older adults. We tested effects of a driving decision aid (DDA) on psychosocial outcomes among older drivers during two‐year follow‐up.MethodsMultisite randomized controlled trial of licensed drivers ages ≥70 with at least one diagnosis associated with increased likelihood of driving cessation, without significant cognitive impairment. The intervention was the online Healthwise® DDA, addressing “Is it time to stop driving?”; controls received National Institute on Aging web‐based information for older drivers. Outcomes were assessed at baseline, 6, 12, 18, and 24 months. Primary outcomes were the Decision Regret Scale, Decisional Conflict Scale (assessing decisional ambivalence or uncertainty), and PROMIS Depression (4a) Scale. Self‐reported Life‐Space Assessment (assessing community mobility), crashes and driving outcomes were also assessed. Using intention‐to‐treat analyses, we tested whether DDA (vs. control) effects on each outcome differed during follow‐up using a study group by time interaction. Longitudinal outcomes were modeled using generalized linear mixed models, accounting for repeated measures, age, site, and baseline visit before vs. during COVID.ResultsWe enrolled 301 participants (age at enrollment: mean 77.1 (range 70–92) years; 51% identifying as female). During follow‐up, the DDA group had less decisional conflict (pinteraction = 0.010) and decision regret (pinteraction = 0.012). The DDA had its greatest effect on decisional conflict immediately post‐intervention (adjusted mean ratio [aMR] = 0.87; 95%CI: 0.79, 0.97) and on decision regret at 12‐month follow‐up (aMR = 0.45; 95%CI: 0.27, 0.72). Odds of depression were similar between groups during follow‐up (pinteraction = 0.237). The intervention did not negatively affect life space, crashes, or other driving outcomes.ConclusionsIn older drivers, the Healthwise® DDA reduced uncertainty and regret about driving decisions during longitudinal follow‐up, without adversely affecting community mobility or crash risk. Use of DDAs in clinical and other settings may reduce the distress older adults often experience when making decisions about driving cessation.
Minimally invasive surgery versus open surgery in advanced stage endometrial cancer
Authors: Lee Jimin , Kim Jeeyeon , Son Joo‐Hyuk , Kong Tae‐Wook , Paek Jiheum , Chang Suk‐Joon 
Published: December 2024

AbstractAimStaging surgery in early stage endometrial cancer has been shown to be feasible and safe with minimally invasive surgery (MIS) in many previous studies. However, there is limited literature on MIS's safety in advanced stages. This study aims to identify factors associated with survival in stage III endometrial cancer and investigate survival differences based on surgical approach.MethodsPatients with stage III endometrial cancer who underwent staging surgery from March 2002 to March 2023 were included in this study. Various clinicopathological features, disease‐free survival (DFS), and overall survival (OS) were evaluated.ResultsAmong the 79 patients included in this study, 20 patients underwent MIS (25.3%) and 59 patients underwent open surgery (74.7%). The open surgery group had a higher prevalence of aggressive histology, a higher median pretreatment CA‐125 level, and a greater number of harvested lymph nodes compared to the MIS group. Five‐year OS and DFS was higher in the open surgery group than in the MIS group (DFS: 67.9% vs. 59.9%, p = 0.046; OS: 74.3 vs. 50.6%, p = 0.008). In multivariate analysis, younger than 55 years old (OR, 2.778; 95% CI, 1.078–7.156; p = 0.034), and open surgery (OR, 3.671; 95% CI, 1.581–8.522; p = 0.002) was related to improved OS.ConclusionsOpen staging surgery showed better survival outcomes when compared to MIS in stage III endometrial cancer patients in our study. For patients who are older than 55 years old and have aggressive histology in endometrial biopsy, considering open surgery may help improve their prognosis, even if preoperative MRI suggests early‐stage endometrial cancer.
Mammalian herbivory alters structure, composition and edaphic conditions of a grey‐dune community
Authors: Francés Alcántara Sandra , Retuerto Rubén , Sánchez Vilas Julia 
Published: December 2024

AbstractQuestionMammalian herbivory affects the structure and composition of plant communities, soil characteristics and intraspecific leaf traits. Understanding the effects of this type of herbivory is particularly relevant in grey dunes, a priority habitat type of the European Union Habitats Directive.LocationSálvora island (NW Spain).MethodsVegetation surveys and sampling were carried out in a coastal grey‐dune community, comparing the structure and composition of plant communities and soil characteristics in plots with herbivory exclusion and plots with herbivore activity, in autumn and spring. Changes in the specific leaf area (SLA), C/N ratio, δ13C and δ15N of two main plant species were also analysed.ResultsThe differentiation between treatments was low in autumn, in contrast to spring results, which demonstrated seasonal variation in the plant community and herbivore behaviour. Spring results showed lower above‐ground dry mass in plots with herbivory due to defoliation, but greater richness and diversity, indicating that intermediate levels of disturbance reduced competition from dominant species. Herbivory treatments were different in terms of species composition, highlighting the positive effects of herbivory on the development of the threatened species Linaria arenaria. Soil temperature and moisture content were higher in herbivory plots because of the suppression of vegetation cover and the effect of trampling, respectively. No differences were detected in the chemical composition of the soil or the SLA, although the variability of these traits was greater in herbivory plots, indicating spatial heterogeneity generated by the activity of herbivores. No differences between treatments were obtained for % C and δ13C, whereas herbivory plots showed lower values of N content and δ15N as an adaptive response to herbivory pressure at the leaf and root level.ConclusionOur findings show that herbivory effects on plant communities vary by season — stronger in spring and weaker in autumn — emphasising the need for seasonal analysis and highlighting disturbance as a driver of spatial heterogeneity.