bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rigid Mini-Thoracoscopy Versus Semirigid Thoracoscopy in Undiagnosed Exudative Pleural Effusion
Authors: Bansal Shweta , Mittal Saurabh , Tiwari Pavan , Jain Deepali , Arava Sudheer , Hadda Vijay , Mohan Anant , Malik Prabhat , Pandey Ravindra Mohan , Khilnani Gopi C. , Guleria Randeep , Madan Karan 
Published: September 2019

Background:
There is debate regarding the ideal instrument for medical thoracoscopy. The authors compared rigid mini-thoracoscopy with semirigid thoracoscopy for thoracoscopic pleural biopsy.

Methods:
Consecutive subjects with undiagnosed exudative pleural effusion were randomized (1:1 ratio) to mini-thoracoscopy or semirigid thoracoscopy groups. The primary objective was a comparison of the diagnostic yield of pleural biopsy. Key secondary outcomes were the comparison of sedative/analgesic dose, operator-rated and patient-rated pain on visual analog scale (VAS), operator-rated overall procedural satisfaction (VAS), pleural biopsy size, and complications between the groups.

Results:
Of the 88 screened subjects, 73 were randomized: 36 to mini-thoracoscopy and 37 to semirigid thoracoscopy. Diagnostic yield of pleural biopsy in the mini-thoracoscopy (69.4%) and semirigid thoracoscopy groups (81.1%) was similar on intention-to-treat analysis (P=0.25). Although the operator-rated overall procedure satisfaction scores were similar between groups (P=0.87), operator-rated pain [VAS (mean±SD), 43.5±16.7 vs. 31.7±15.8; P<0.001] and patient-rated pain (VAS, 41.9±17.3 vs. 32.1±16.5; P=0.02) scores were greater in the mini-thoracoscopy group. Mean dose of fentanyl and midazolam received was similar between the 2 groups (P=0.28 and 0.68, respectively). Biopsy size was larger in the mini-thoracoscopy group (16.1±4.5 vs. 8.3±2.9 mm; P<0.001). Three minor complications occurred in the mini-thoracoscopy group and 6 in the semirigid thoracoscopy group (P=0.11). There were no serious adverse events or procedure-related mortality.

Conclusion:
Diagnostic yield of rigid mini-thoracoscopy is not superior to semirigid thoracoscopy. Use of semirigid thoracoscope may provide greater patient comfort.
Dupuytren, Ledderhose, and Peyronie Diseases After Primidone Use For Essential Tremor
Authors: Vasconcellos Luiz Felipe R. , Nassif Daniel , Spitz Mariana 
Published: September 2019

Introduction:
Dupuytren, Ledderhose, and Peyronie diseases are chronic fibrotic conditions related to progressive fibrosis of the palmar fascia, plantar fascia, and tunica albuginea, respectively. These conditions have been associated with antiepileptic drug use, mainly phenobarbital and primidone.

Case Report:
A 71-year-old man developed simultaneous Dupuytren, Ledderhose, and Peyronie diseases after primidone use for essential tremor.

Conclusions:
There are a few reports associating barbiturate use to connective tissue disorders, and some suggest that drug withdrawal may result in a better prognosis. Therefore, physicians must be aware of such adverse events when caring for patients on long-term barbiturate use.
Outcomes and Predictors of Revision Labiaplasty and Clitoroplasty after Gender-Affirming Genital Surgery
Authors: Boas Samuel R. , Ascha Mona , Morrison Shane D. , Massie Jonathan P. , Nolan Ian T. , Shen Jacson K. , Vyas Krishna S. , Satterwhite Thomas 
Published: September 2019

Background:
Penile inversion vaginoplasty is the most common gender-affirming procedure for transfeminine patients. Patients undergoing this procedure may require revision labiaplasty and clitoroplasty. This study describes complications and outcomes from the largest reported cohort in the United States to undergo penile inversion vaginoplasty with subsequent revision labiaplasty and/or clitoroplasty.

Methods:
A retrospective chart review was performed of a single surgeon’s experience with penile inversion vaginoplasty with or without revision labiaplasty and/or clitoroplasty between July of 2014 and June of 2016 in a cohort of gender-diverse patients assigned male at birth. Patient demographic data, complications, and quality of life data were collected. Univariate and multivariate comparisons were completed.

Results:
A total of 117 patients underwent penile inversion vaginoplasty. Of these, 28 patients (23.9 percent) underwent revision labiaplasty and/or clitoroplasty, with nine patients (7.7 percent) undergoing both procedures. Patients who underwent penile inversion vaginoplasty necessitating revision were significantly more likely to have granulation tissue (p = 0.006), intravaginal scarring (p < 0.001), and complete vaginal stenosis (p = 0.008). The majority of patients who underwent revision labiaplasty and/or clitoroplasty reported satisfaction with their final surgical outcome (82.4 percent) and resolution of their genital-related dysphoria (76.5 percent).

Conclusions:
Patients who developed minor postoperative complications following penile inversion vaginoplasty were more likely to require revision surgery to address functional and aesthetic concerns. Patients responded with high levels of satisfaction following revision procedures, with the majority of patients reporting resolution of genital-related dysphoria. Transfeminine patients who undergo penile inversion vaginoplasty should be counseled on the possibility of revisions during their postoperative course.

CLINICAL QUESTION/LEVEL OF EVIDENCE:
Therapeutic, III.
Alterations in NKG2A and NKG2C Subsets of Natural Killer Cells Following Epstein–Barr Virus Reactivation in CTLA4Ig-based Haploidentical Transplantation Is Associated With Increased Chronic Graft-Versus-Host Disease
Authors: Jaiswal Sarita Rani , Bhakuni Prakash , Bhagwati Gitali , Aiyar Hema Malini , Chakrabarti Aditi , Chakrabarti Suparno 
Published: September 2019

Background.
The impact of newer approaches to haploidentical transplantation on Epstein–Barr virus (EBV) is largely unknown.

Methods.
We prospectively evaluated the incidence of EBV reactivation and its impact on transplantation outcomes in 71 patients undergoing haploidentical transplantation with posttransplantation cyclophosphamide in combination with CTLA4Ig-based T-costimulation blockade.

Results.
Eight patients developed EBV reactivation at a median of 96 days with no incidence of lymphoproliferative disorder. There was no impact of EBV reactivation on acute graft-versus-host disease (GVHD), nonrelapse mortality, progression-free, or overall survival. Despite an overall incidence of 19%, there was a significant increase in chronic GVHD following EBV reactivation (62.5% versus 8%; P = 0.01). NKG2Apos subset of CD56dim natural killer cells increased substantially and persisted following EBV reactivation and chronic GVHD, with a reciprocal decrease in NKG2Cpos subset, whereas the reverse was witnessed in those without chronic GVHD (P < 0.01). Increase in NKG2Cpos subset and a decrease in the NKG2Apos subset were witnessed within 3 months of subsidence of chronic GVHD.

Conclusions.
Thus, CTLA4Ig-based haploidentical transplantation was associated with a low incidence of EBV reactivation without EBV-lymphoproliferative disorder. However, EBV reactivation was associated with a sustained alteration in NKG2A and NKG2C subsets of CD56dim natural killer cells which might have a pathogenic role in chronic GVHD.
Constrictive Pericarditis After Lung Transplantation
Authors: Armstrong Jenna L. , Wojnarski Charles M. , Choi Ashley Y. , Hartwig Matthew G. , Klapper Jacob A. , Haney John C. , Milano Carmelo A. , Daneshmand Mani A. 
Published: September 2019

Background.
Constrictive pericarditis is a rare, but increasingly recognized long-term postoperative complication of lung transplantation. Heightened clinical suspicion, improved diagnostic imaging, and effective surgical treatment of the disease have led to progressive awareness of the pathology. We present our institutional experience with constrictive pericarditis after lung transplant in an effort to investigate the cause and natural history of the disease.

Methods.
From October 2005 to October 2018, 1234 patients underwent orthotopic lung transplantation at Duke University Hospital. An institutional database was queried to identify incident patients and determine baseline clinical data. At a median of 11.2 months (interquartile range = 4.6–28.6 mo), 10 patients (0.8%) developed constrictive pericarditis. Simple descriptive statistics were used to describe cohort characteristics and identify variables associated with constrictive pericarditis after lung transplantation.

Results.
The indication for transplantation at index operation was idiopathic pulmonary fibrosis in 8 of 10 patients (1.2% of the 760 restrictive lung disease patients transplanted in the same time period). All 10 patients presented with worsening dyspnea and pleural effusions. Right heart catheterization confirmed constrictive physiology in all cases. Eight patients underwent pericardiectomy with improvement in cardiovascular hemodynamics and resolution of symptoms with no 30-day mortality.

Conclusions.
Diagnosis of constrictive pericarditis should be considered in patients with new-onset heart failure symptoms or recurrent pleural effusions within 2 years of lung transplantation. Idiopathic pulmonary fibrosis may be associated with increased risk for constrictive pericarditis. Pericardiectomy is a safe and effective treatment for posttransplant constrictive pericarditis.
Slepyan's dynamic contribution to studies of fracture
Authors: Marder M. 
Published: September 2019

After a brief review of atomistic theories of defect dynamics in solids, a summary of Slepyan's first computation of dynamic fracture in a lattice is presented. Some of the main extensions and clarifi- cations of the original physical picture are then summarized. Many molecular dynamics simulations of fracture would benefit if Slepyan's work were better known.
This article is part of the theme issue ‘Modelling of dynamic phenomena and localization in structured media (part 1)’.
Determinants of agri-lending in Kenya
Authors: Maloba Michelle , Alhassan Abdul Latif 
Published: September 2019

PurposeThe purpose of this paper is to examine the factors that influence financial institutions’ lending to the agricultural sector in Kenya.Design/methodology/approachThe paper employs a panel data of 15 licensed financial institutions (commercial banks and deposit-taking microfinance institutions) from 2011 to 2016. The random effects and ordinary least squares panel corrected standard errors estimation techniques are employed to estimate the effect of liquidity, size, equity, lending rate (LR), type of financial institution and non-performing loans on agri-lending.FindingsThe results indicate that only 3.9 per cent of loan portfolio of the sampled financial institutions were advanced to the agricultural sector over the study period. From the panel regression analysis, the paper finds agricultural credit risk to reduce lending to the agricultural sector while size, LR and type of financial institution were observed to significantly increase agricultural lending. Compared to 2011, agri-lending was also observed to have declined between 2012 and 2015.Practical implicationsThe findings highlight important indicators for enhancing lending to the agricultural sector in Kenya and other emerging economies.Originality/valueAs far as the authors are concerned, this presents the first empirical evidence on the determinants of agri-lending by financial institutions in Kenya.
Bank diversification strategy and intellectual capital in Ghana: an empirical analysis
Authors: Duho King Carl Tornam , Onumah Joseph Mensah 
Published: September 2019

Purpose
The purpose of this paper is to examine the impact of intellectual capital and its components on bank diversification choice.

Design/methodology/approach
Both asset and income diversification are computed and an unbalanced panel data set of 32 banks covering the period 2000–2015 have been used. The panel corrected standard error regression has been used to account for serial correlation and heteroscedasticity.

Findings
The study found that intellectual capital determines the choice of diversifying. Precisely, intellectual capital motivates asset diversity but it dissuades income diversification. Human capital and structural capital are major components that determine asset diversity decisions. Income diversification decision, in this case to choose a focus strategy, is determined by human capital. This gives credence for the human capital theory in Ghana. Competition encourages a focus strategy. Bank size and leverage enhances income diversification while stock exchange listing and government ownership fosters the focus strategy.

Practical implications
Diversification strategy, knowledge base of staff, corporate governance and internal control have been considered as factors leading to the collapse of some Ghanaian banks in 2017–2018. The study provides relevant insights for regulators, decision support units and corporate boards. Intellectual capital and value added metrics should be used for modelling and decision making as they have value relevance.

Originality/value
This is a premier study that has examined the nexus between diversification strategy and intellectual capital in banks.
The usage of green building concept to reduce operating costs (study case of PT. Prodia Widyahusada)
Authors: Tjenggoro Felix Novendra , Prasetyo Khusnul 
Published: September 2019

Purpose
The purpose of this paper is to emphasize green building concept usage and its effect on operating costs and uses Grha Prodia, a building with a green concept owned by PT. Prodia Widyahusada.

Design/methodology/approach
This research will test whether Grha Prodia could earn Leadership in Energy and Environmental Design (LEED) certification based on the aspects that it has and it will also compare the operating costs of Grha Prodia with Prodia Tower. The two main theories used in this research are cost and green building.

Findings
The result of this research is Grha Prodia is considered as a green building and it could earn LEED certification if the current aspects are continuously implemented and maintained.

Originality/value
Moreover, it can fulfill all prerequisite credits in each criterion and further enhance it by fulfilling optional credits in all criteria available. Grha Prodia is also able to demonstrate lower operating costs than a regular building, with 63 percent less water usage and 53 percent less electricity usage.
The effect of enterprise risk management (ERM) on firm value in manufacturing companies listed on Indonesian Stock Exchange year 2010-2013
Authors: Iswajuni Iswajuni , Manasikana Arina , Soetedjo Soegeng 
Published: September 2019

Purpose
The purpose of this paper is to identify the effect of enterprise risk management (ERM) with firm size, ROA and managerial ownership as control variables on firm value that is proxied by Tobin’s Q.

Design/methodology/approach
Population of this research was manufacturing companies listed on the Indonesian Stock Exchange (IDX) in 2010–2013. The used method in this research is multiple linear regression-ordinary least square and hypotheses testing using t-test to test the regression coefficients with level of significance of 5 percent.

Findings
The results showed that ERM, ROA and size of the company have a significant positive effect on the firm value. While the managerial ownership has a significant negative effect on the firm value.

Originality/value
The results showed that firm value increases as ERM, ROA and size of the company improves. While the managerial ownership has a significant negative effect on the firm value.
Evaluating factors of profitability for Indian banking sector: a panel regression
Authors: Bansal Rohit , Singh Arun , Kumar Sushil , Gupta Rajni 
Published: September 2019

Purpose
The purpose of this paper is to quantify several measures to examine the determinants of profitability for the listed Indian banks. The authors include both public sector (PSUs) and private sector’s banks in the study. The authors have taken all the banks that are registered on the Bombay stock exchange (BSE) in the sample. This paper also intends to identify the association between the net profit margin (PM) and return on assets (ROA) with the several other independent variables of the Indian banking sector including private banks and public banks over the past six years starting from April 1, 2012 to March 31, 2017. Therefore, a sample of 39 listed banking companies and total 195 balanced observations are selected for the analysis purpose.

Design/methodology/approach
The authors have used profitability as a dependent variable represented by net PM, ROA and several financial ratios as independent variables. Financial statement and income statement of all listed banks were obtained from BSE and particular company’s website. Panel data regression has been analyzed with both the descriptive research techniques, i.e., fixed effects and random effects. The authors also verified both panel techniques with Hausman’s specification test, which is a widely used procedure for selecting a panel effect. The authors applied PP – Fisher χ2, PP – Choi Z-statistics and Hadri to testing whether the data set is free from unit root problem and data set is a stationary series.

Findings
Results imply that interest expended interest earned (IEIE) and credit deposit ratio (CRDR) reduced the profitability of private banks in India. IEIE, CRDR and quick ratio (QR) reduced the profitability of public banks in India, while cash deposit ratio (CDR) and Advances to Loan Funds (ALF) increased the effectiveness of public banks. Under the total banks IEIE, CRDR reduced the profitability, on the other side, CDR, ALF and Total Debt to Owners Fund (TDOF) increased the profitability of total banks in India. Under the dependency of ROA, CRDR and TDOF reduced the return of private banks in India, while CDR, ALF and QR enhanced the profitability of private banks.

Originality/value
No variables found significant under public banks while taking ROA as a dependent variable. Under the overall banking data, CRDR reduced the profitability. On the other side, capital adequacy ratio and ALF increased the profitability of total banks in India. The findings of this study will support policy creators, financial executives and investors in constructing investment decisions.
Request for information frequency and their turnaround time in construction projects
Authors: Aibinu Ajibade A. , Carter Simon , Francis Valerie , Vaz-Serra Paulo 
Published: September 2019

PurposeThe purpose of this paper is to study the nature of request for information (RFIs) on construction projects by using data analytics to understand the frequency of RFIs, when they occur on projects, and the relationship between project characteristics and frequency of RFIs and between project characteristics and RFI turnaround time.Design/methodology/approachA data-analytic approach using RStudio and Minitab software on 168 construction project cases in Australia and New Zealand involving 1,032,949 correspondences and 53,042 RFI event records made available by Aconex, one of the world largest cloud-based project management platform.FindingsLarge and complex projects tend to have significantly larger number of RFI events per day and longer RFI turnaround when compared with smaller and less complex projects. Projects with fewer users per organisation recorded a higher RFI turnaround time when compared with projects with more users per organisation – users mean persons involved in managing the project using the online platform (an index of project complexity). RFIs occur early on less complex projects and occur later on more complex projects.Research limitations/implicationsBenchmarks of RFI incidences and turnaround time have been developed for various project characteristics and, practitioners can use them to monitor the RFI performance of projects. Organisations need to pay greater attention to staffing levels needed to handle RFIs to reduce RFI turnaround time.Originality/valueA data-analytic study of RFI yielded insights for managing RFIs. The findings of previous studies on RFIs are difficult to generalise because they are based on single project case study. The influence of project characteristics on RFI frequency and RFI turnaround time is not yet known.
Antibacterial effect of verjuice against food-borne pathogens
Authors: Öncül Nilgün , Karabiyikli Şeniz 
Published: September 2019

PurposeNowadays, natural products are preferred for food safety and preservation due to the demand of consumers. The industrial methods which have been in use for a long period of time have had an adverse impact on organoleptic properties of foods or on human health. The purpose of this paper is to investigate the antibacterial effects of unripe grape products on natural and inoculated micro-flora of lettuce as an alternative functional and natural antibacterial agent for consumers and food industry.Design/methodology/approachThe antibacterial effects of products on initial micro-flora of lettuce were detected. The lettuce samples were treated with products for different treatment times (0, 5 and 10 min). The antibacterial effects of products against inoculated micro-flora on lettuce were obtained. Lettuce samples were separately inoculated with food-borne pathogens (~4 log CFU/g) and treated with products for the same treatment periods.FindingsUnripe grape products decreased the initial micro-flora by approximately 1 log CFU/g in 5 min. Unripe grape products dramatically inhibited the inoculatedE. colion lettuce samples right after the treatment. Majority of the unripe grape products decreased the number ofS. TyphimuriumandL. monocytogenesto an undetectable level in 5 min.S. aureuswas the most resistant microorganism among the tested cultures. It was concluded based on the conspicuous results on the inhibition ofE. coli,S. TyphimuriumandL. monocytogenesthat unripe grape products can be considered as natural antimicrobial agents for food safety.Originality/valueThis study is also valuable since it enables thein situtesting of the potential usage of unripe grape products against food-borne pathogens.
Financial risk reporting practices: systematic literature review and research agenda
Authors: Khandelwal Chandni , Kumar Satish , Verma Deepak , Pratap Singh Harsh 
Published: September 2019

PurposeThis paper aims to review the status of literature on financial risk reporting practices (FRRP) for the purpose of synthesizing mounting literature to suggest the relevant risk reporting measure across the globe.Design/methodology/approachUsing a systematic literature review method, a total of 61 articles from 42 referred journals and international conferences published from 2000 to 2018 are reviewed.FindingsIt has been found that despite the growing attention on and importance of corporate risk disclosure, academic literature on corporate risk disclosure is limited. Also, research linking risk disclosure with governance mechanisms is rare. Scrutiny of the literature on corporate risk disclosure shows that most of the researchers have focused on the limited or single period to examine the risk disclosure practices, determinants and corporate performance. The limitation of these studies is that with single period data analysis generalization of findings is limited. Findings of longitudinal studies are more reliable, and in extant literature, only a few studies have used data of more than a single period.Originality/valueThis paper contains a comprehensive listing of publications on financial risk reporting and corporate disclosure and its classification according to various attributes. The paper will be useful to researchers, finance professionals and others concerned with risk reporting to understand the importance of risk disclosure.