bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dampening of positive affect partially accounts for the association between women’s reported history of child maltreatment and current depressive symptoms
Authors: STONE LINDSEY , Sylvester Alisha 
Published: November 2024

Abstract

Background
Child maltreatment exerts lasting effects on emotion regulation, which in turn accounts for adult’s risk for psychopathology such as depression. Child maltreatment is associated with impairments in reward sensitivity (responding to positive stimuli in-the-moment) as well as chronic anhedonia, lack of positive moods and pleasure to environmental stimuli. To date though, emotion regulation strategies that account for these deficits in positive moods and responses is limited. We examined the role of positive rumination and dampening of positive affect, both voluntary emotion regulation strategies. We hypothesized that alterations in positive rumination and dampening would explain the association between women’s history of child maltreatment and risk for current depressive symptoms. Given that child maltreatment also impairs emotion regulation of negative affect, we also explored the unique effects of positive affective strategies after controlling for dysphoric rumination.
Methods
Undergraduate women (n = 122) completed surveys on child maltreatment, depressive symptoms, and their tendency to dampen or engage in positive rumination in response to positive affect, reflecting cross-sectional data. The PROCESS macro, model 4 was run in SPSS to examine the extent to which emotion regulation strategies accounted for the association between child maltreatment history and current depressive symptoms.
Results
Child maltreatment history was associated with a higher tendency to dampen positive affect but was not linked with positive rumination. Dampening partially explained the link between child maltreatment and women’s current depressive symptoms. Dampening continued to account for unique variance in the association between child maltreatment and depressive symptoms (β = 0.13) after including rumination in the model.
Conclusions
Results suggests that emotion suppression strategies among child maltreatment survivors may also extend to positive affect, and specificity in regulation strategies are altered. Currently dysphoric women with a history of child maltreatment tend to dampen their positive moods and reactions to events, which has immediate treatment implications for this population. Future, longitudinal research is warranted to clarify the role of alterations in positive emotion regulations strategies in understanding how child maltreatment fosters risk for psychopathology such as depression.
Metallothionein 2A as a prognostic marker promotes glioma progression
Authors: Gong Li , Luo Ming , Deng Xinzhou , Li Haixia , Cao Nan , Feng Wei , Chai Jingjing , Luo Zhiguo , Huang Hongyan 
Published: November 2024

Abstract

Background
Metallothionein 2A (MT2A) plays a significant role in carcinogenesis and metastasis, while its function in glioma remains unclear. This study aims to investigate the function and mechanisms of MT2A in glioma.
Methods
Raw data pertaining to glioma were collected from the Chinese Glioma Genome Atlas database and The Cancer Genome Atlas database to explore the expression and role of MT2A. In vitro and in vivo experiments were conducted to elucidate the function of MT2A and the underlying molecular mechanisms involved in glioma cells.
Results
MT2A was elevated in glioma patients with certain clinical characteristics, and high levels of MT2A were not only associated with poor prognosis but also served as a valuable prognostic indicator in glioma. The overexpression of MT2A increased the proliferative, migratory, and invasive capabilities of glioma cells, and upregulated the expression of epithelial‒mesenchymal transition (EMT)-related proteins, including TGF-β1, Vimentin, Twist1, and Slug in vitro and in vivo, whereas the downregulation of MT2A had the opposite effects. Knockdown of MT2A induced G2/M phase arrest and enhanced apoptosis in glioma cells.
Conclusions
MT2A promotes glioma progression by regulating cell proliferation, migration, and invasion as well as the EMT process, suggesting its potential utility as a prognostic marker for glioma.
Unexpected Neurological Deterioration Following Occipitocervical Fusion Surgery
Authors: Nakagawa Takane , Takahashi Hiroshi , Miura Kousei , Gamada Hisanori , Okuwaki Shun , Sakashita Kotaro , Sunami Takahiro , Ogata Yosuke , Noguchi Hiroshi , Funayama Toru , Koda Masao 
Published: November 2024

Abstract

Background
Occipitocervical posterior decompression and fusion (O-C fusion) surgery is occasionally required for treating high cervical myelopathy due to atlantoaxial subluxation. The advance of the instrumentation systems has led to favorable clinical outcomes following O-C fusion surgery. However, the rate of perioperative complications in O-C fusion surgery is relatively high, including instrumentation failure, respiratory complications, and dysphagia. Here we report a rare case involving an unexpected deterioration of myelopathy following O-C fusion surgery.
Case presentation:
A 49-year-old male was transported to our hospital by ambulance with left-sided upper and lower limb paralysis. At the initial visit, a neurological examination revealed left upper limb weakness (MMT grade 2). X-ray and CT revealed severe atlantoaxial subluxation due to Os Odontoideum, while MRI revealed significant spinal cord compression at the C2 level. On the diagnosis of acute exacerbation of high cervical myelopathy, an O-C2 posterior decompression and fusion surgery including C1 laminectomy was performed. Postoperatively, the patient exhibited a deterioration in right-sided upper limb paralysis (MMT grade 2), despite proper implant placement confirmed by CT. During two weeks postoperatively, there was no improvement in the right-sided upper limb paralysis, and bilateral deep sensory impairment worsened. Follow-up X-rays revealed a progressive decrease in the O-C2 angle and dynamic X-ray imaging demonstrated a recurrence of instability at the O-C2 level. On the diagnosis of the instrumentation failure, a revision surgery was performed 3 weeks after the primary surgery. Intraoperative findings revealed instability at the C2 screw head and loosening of the set screw on the C2 screw head. To achieve a more secure fixation, we extended the fusion to C4 with a triple rod connection. Following the revision surgery, his myelopathy and paralysis gradually improved. At the final follow-up 6 months after surgery, X-rays showed that O-C2 was firmly stabilized.
Conclusions
In O-C fusion surgery, screw head fixation close to the O-C rod bending site may result in unexpected instrumentation failure.
Assessing Spatial and Temporal Urban Air Quality Variabilities with the Vaisala AQT530 Monitor
Authors: Papaconstantinou Roubina , Bezantakos S. , Pikridas M. , Parolin M. , Stylianou M. , Savvides C. , Sciare J. , Biskos George 
Published: November 2024

Abstract

Low-cost gas and particle sensors can significantly increase the spatial coverage of Air Quality (AQ) monitoring networks in urban settings. Considering that the accuracy of such sensors is not high enough to replace reference instruments for AQ monitoring, the question is whether they can be used to capture spatial differences among different stations, as well as temporal trends and month-to-month variabilities at a specific location. To investigate that, we carried out measurements over a period of 19 months with two Vaisala AQ Transmitters-Monitors (Model AQT530), collocated with reference-grade instruments, in two AQ monitoring stations in Nicosia: an urban traffic and an urban background station. The AQ monitors employ Low-Cost Sensors (LCSs) for gaseous pollutants (i.e., CO, NO2, NO, and O3) and Particulate Matter (PM). Statistical analysis of the reference measurements shows that the mean concentrations of the pollutants at the two stations, determined over the entire study period and for each month separately, were significantly different. Analysis of the LCS measurements showed that that the reproducibility of the NO2, NO, O3, and PM2.5 sensors, over a period when these were co-located at the traffic station, is poor, excluding them from further investigating their ability to capture spatial differences between different stations. The CO and PM10 measurements from the AQ monitors effectively captured the differences in pollutant concentrations between the two stations when averaged over the entire study period or on a monthly basis, with few exceptions during specific months depending on the sensor. These LCSs were also able to capture concentration differences between the two stations on a daily or monthly basis, as long as those were above a certain threshold for each pollutant. The CO and PM sensors captured the month-to-month trend over the entire period of the measurements, similarly to the reference instruments, while the NO2, NO and O3 sensors did not, mainly due to their sensitivity to the environmental conditions. Despite that, all sensors captured the statistical significance of the month-to-month concentration differences at the same station, with the PM2.5 measurements showing the highest capability of doing so in accordance with the reference instruments.
Research on the Synergistic Relationship between Urban Tourist Attractions and Green Infrastructure in Japanese Cities Based on Green Tourism
Authors: YANG Zhuojing , Homma Riken 
Published: November 2024

Abstract

In the context of sustainable development, the concept of green tourism has garnered widespread attention. As more people choose cities as their travel destinations, this trend not only promotes urban economic development but also impacts urban ecosystems. Based on this, this paper proposes the concept of coordinated planning for urban green infrastructure (UGI) and urban tourist attractions. By studying and conducting a comparative analysis of the synergy between green infrastructure and urban tourist attractions in Tokyo, Kyoto, and Kumamoto, this study explores the relationship between green infrastructure and urban tourist attractions in cities with different levels of economic development and population sizes. The study mainly considers the spatial correlation between UGI and urban tourist attractions.
Incidence, sutcome and trends of in-hospital cardiac arrest over a ten-year period in a swiss tertiary hospital
Authors: Oechslin Luca , Abplanalp Jan , Biaggi Patric , Hadzalic Hasan , Britschgi Daniel , Luz Christian , Url Alfons , Stocker Reto , Wyss Christophe 
Published: November 2024

Abstract

Objective:
The aim of this retrospective study was to analyze the incidence, characteristics, outcomes and potential predictors of outcome of in-hospital cardiac arrest (IHCA) occurring from 2012 to 2022 at a tertiary hospital in Switzerland.
Methods:
All in-hospital cardiac arrest missions over a ten-year period were retrospectively analyzed. Subsequently, statistical analysis was conducted to identify variables influencing the outcome (outcomes of interest were return of spontaneous circulation (ROSC) and survival after 6 and 12 months).
Results:
Over a ten-year period, there were 364 resuscitations, resulting in an overall incidence of 1.87 resuscitation per 1000 hospitalizations. ROSC was achieved in 63.4% and 37.4% were alive at 12 months. In 71.2% the initial rhythm was unshockable. Observed cardiac arrest and continuous ECG monitoring were significant positive predictors for ROSC and improved survival. Older age was associated with worse survival throughout the study period. Over the ten-year study period both incidence and outcomes of IHCA were unchanged.
Conclusion:
IHCA was infrequent but associated with high mortality rates. Continuous ECG monitoring emerged as a robust predictor for achieving ROSC and for improved survival following IHCA.
Untargeted Metabolomics and Proteomics-based Research of the Long-term Exercise on Human Body
Authors: Zhuang Wenqian , Wang Yang , Xu Xin , Zhao Jingjing 
Published: November 2024

Abstract

Regular long-term exercise can benefit the body and reduce the risk of several diseases, such as cardiovascular disease, diabetes, and obesity. The proteomic and metabolomic changes, as well as the physiological responses associated with long-term exercise, remain incompletely understood. To investigate the effects of long-term exercise on the human body, 14 subjects with long-term exercise habits and 10 subjects without exercise habits were selected for this study. Morning urine samples were collected and analyzed for untargeted metabolomics and proteomics using liquid chromatography-mass spectrometry. A total of 404 differential metabolites and 394 differential proteins were screened in this research, and the analysis results indicated that long-term exercise may affect energy metabolism, amino acid synthesis and metabolism, nucleotide metabolism, steroid hormone biosynthesis, and inflammatory response. These findings offer a more comprehensive understanding of the molecular effects of long-term exercise on the human body and provide a basis for future research exploring the underlying mechanisms.
Control of tomato black leaf mold by disinfecting agricultural materials contaminated with overwintering causal fungus in commercial greenhouses.
Authors: Kirino Namiko , Kawaguchi Akira 
Published: November 2024

Abstract

In this study, we evaluated the effect of disinfecting agricultural materials contaminated with Pseudocercospora fuligena on tomato black leaf mold (BLM) using two methods: spraying with benzothiazole solution (referred to as "spraying") and smoking with Tetrachloroisophthalonitrile (TPN) smoke agent (referred to as "smoking").
Meta-analysis of the conidial germination data showed a combined relative risk (RR) of 0.20 (95% CI: 0.14–0.27) for spraying and 0.06 (95% CI: 0.04–0.08) for smoking, indicating significant inhibition of conidial germination.
The effect of material disinfection using both methods on BLM occurrence were investigated in 14 greenhouses across four fields. In two experiments conducted in 2014, the survival period of tomato plants in the disinfected greenhouses was extended by 11 and 32 days using the spraying method and by 11 and 26.5 days using the smoking method (Kaplan–Meier) ,compared with ones in non-disinfected greenhouses. The general linear mixed model (GLMM) analysis of disease incidence data from tomato leaves during the late cultivation period from experiments in 2014, 2015, and 2021 revealed significant associations between disinfection and BLM occurrence. Subsequently, the meta-analysis results revealed an RR of 0.66 (95% CI: 0.63–0.70) in two experiments of spraying and an RR of 0.80 (95% CI: 0.74–0.87) in four experiments of smoking.
In conclusion, disinfection of P. fuligena-contaminated agricultural materials effectively eliminated primary BLM infection and tended to slightly reduce disease occurrence during tomato cultivation. This study is the first to evaluate the impact of disinfecting conidia-contaminated materials on BLM occurrence in field experiments.
Performance Evolution of the Nano Boron Nitride Enhanced Bone Cement Composites
Authors: Wang Hong , Zhang Kangrui , Niu Wenduo , Min Sicong , Lu Fan , Zhang Shifeng , Gao Wensheng , Han Hua , Xia Yayi 
Published: November 2024

Abstract

Bone cement is a research hotspot and has been partially applied in the field of bone repair thanks to the good mechanical, physical and antibacterial properties. However, the easy wear and high temperature during curing characteristics would cause surrounding tissue necrosis, which seriously limits the wider application to some extent. In this work, the hexagonal boron nitride (h-BN) nano flakes were optimized to enhance the bone cement matrix (PMMA) via mechanical doping. The doping of h-BN into PMMA results in an improved mechanical, thermal-conductivity, wear-resistance properties, in addition, the h-BN has no significant impact on cell activity. What’s more, the co-modification of PMMA with h-BN and Vancomycin (Va) endows the bone cement composites with more persistent drug release characteristics. This comprehensive performance evolution evaluation provides a reference for the innovative application of modified bone cement.
A Framework Built on Reliability and Deep Learning for Detecting Attacks in the Home Area Network of Smart Grids
Authors: Ethirajan Venkatraman 
Published: November 2024

Abstract

The integration of the Internet of Things (IoT) into our daily lives finds application in various domains, with the Home Area Network (HAN) being a notable facet. Within the realm of IoT applications, the Smart Grid stands out as an intelligent power network characterized by bidirectional flows of electricity and information. This interconnected system utilizes advanced communication infrastructure to efficiently manage the operation of all linked components, ensuring a reliable and sustainable electricity supply. The Home Area Network serves as a dedicated network linking devices within homes, including electrical vehicles. As the HAN market evolves within the smart grid sector, offering diverse solutions for residential needs, it faces challenges associated with the increasing reliance on information technology. The deep integration of electrical components with computing information in cyberspace renders the system susceptible to cyber-attacks, posing concerns for both power system operators and users. These attacks have the potential to compromise the control system of the power grid, leading to disruptions and incidents. This paper introduces a model approach and validates the security of HAN networks. A novel Reliability Oriented Recursive Energy Effective Redirecting Algorithm [ROREERA] is proposed, incorporating a data encryption scheme for secure data transfer within the HAN. The encryption and decryption of data employ the Honey Crock algorithm. To enhance security further, a deep auto-encoder is employed for intrusion detection, safeguarding the HAN against cyber-attacks. The entire experimentation process is conducted within the Mat lab environment.
Novel Conjugated 5-Alkenyl Rhodanine Tethered 1,4-Benzodioxane Derivatives as Dual-Chitinases Inhibitors to Hinder the Growth of Asian Corn Borer
Authors: Chen Jinxiu , Shi Dongmei , Jiang Zhiyang , Zou Renxuan , Zhang Jingyu , Han Qing , Wang Na , Xu Zhijian , Yang Qing , Duan Hongxia 
Published: November 2024

Abstract

OfChtI and OfChi-h are ideal targets for developing agricultural inhibitors against Ostrinia furnacalis. In order to further confirm the importance of conjugated systems in rhodanine derivatives, sixteen novel 1,4-benzodioxane-tethered-rhodanine derivatives were designed and synthesized with or without C = C double bond of 5-alkenyl rhodanine skeleton. Among them, compounds 3a ~ 3h, with preserved 5-alkenyl rhodanine skeleton, all exhibited much better inhibitory activities against both OfChtI and OfChi-h, compared to that of the corresponding reduced compounds 4a ~ 4h without its C = C double bond. The inhibitory mechanism demonstrated that the 5-alkenyl rhodanine conjugated plane was conducive to improving the binding affinity with both two chitinases. Compound 3g was identified as the most potential dual-chitinases inhibitor against OfChtI (Ki = 2.57µM) and OfChi-h (Ki = 2.03µM). The bioassay study also indicated that compound 3g displayed the best insecticidal activity against O. furnacalis and distinctive sublethal effect in regulating its growth and development. These 1,4-benzodioxane-tethered-rhodanine derivatives deserved further investigation as novel dual-chitinases inhibitor candidates in the control of O. furnacalis.
Genome sequence-based identification of bacteria nodulating Mimosa pudica growing in Eastern Himalayas and Western Ghats of India and description of Cupriavidus mimosae sp. nov. and Cupriavidus gehlotii sp. nov
Authors: Sharma Lekha , Khairnar Mitesh , Pansare Aabeejjeet , Medicherla Krishna Mohan , Goswami Girish K , Rahi Praveen 
Published: November 2024

Abstract

The invasive weed Mimosa pudica (wild) is widespread in India’s tropical regions and nodulated by beta-rhizobia, including Cupriavidus and Paraburkholderia. This study investigates the genetic diversity of rhizobia associated with M. pudica in the Eastern Himalayan (EH) and Western Ghat (WG) regions of India. MALDI-TOF-MS and 16S rRNA gene phylogeny identified EH rhizobia as Paraburkholderia, while WG rhizobia belonged to Cupriavidus. Core-gene phylogeny (bac120 genes) and average nucleotide identity (ANI) values confirmed EH strain SKND8 as Paraburkholderia caribensis. In contrast, WG strains WGtm5T and WGlv3T clustered within the Cupriavidus taiwanensis species complex but had ANI values below 95.1% with validly published species, suggesting they are novel species. Distinct clusters in bac120 gene phylogeny and ANI values below 95.8% further indicate that both strains represent different species. Major fatty acids identified in WGtm5T and WGlv3T included C16: 0, C16:1 ꙍ7c and/or C16:1 ꙍ 6c and C18: 1ꙍ 7c and/or C 18: 1 ꙍ 6c. Based on ANI values, core-gene phylogeny, and phenotypic data, we proposed two novel species, Cupriavidus mimosae sp. nov for WGtm5T (MCC4888T = KACC 22828T) and Cupriavidus gehlotii sp. nov for WGlv3T (MCC4890T = KACC 22827T). The presence of nodulation and nitrogen-fixation genes and nodule formation in Vigna radiata and Vigna unguiculata by strain SKND8, WGtm5T and WGlv3T highlighted their nitrogen fixation potential. Additionally, WG strain WGmk3, identified as Herbaspirillum huttiense, lacks nodulation genes and may be an endophyte of M. pudica.
A digital health intervention model using community health workers: findings from primary health services in rural Bangladesh
Authors: Zaman Marzia , Hridhee Rubaiyat Alim , Bhuiyan Refat Ahmed , Gomes Charles Aunkan , Rahman Md. Mashiar , Sheikh Mohammed Shariful , Sarker Farhana , Mamun Khondaker A. 
Published: November 2024

Abstract

Objective: This paper aims to understand people’s health conditions after a digital health intervention model was implemented in a rural area of Bangladesh. We analyzed the health conditions of the served population 18 months after the operation.
Methods: The data presented in this paper are obtained from the model’s pilot implementation in one area in Bangladesh. Community health workers provided monthly health services at doorsteps while collecting various sociodemographic, health, economic, and environmental data. We presented the findings from the collected data on user health. Sociodemographic and health measurement data were presented as proportions with 95% confidence intervals (CIs). Multivariate logistic regression was used to analyze the association between diseases and their respective risk factors. We compared the health vitals across three consecutive periods to determine improvements in health outcomes over time.
Results: The model served 32,581 people from 7,090 households during this operation. We found that 21.76% of the served population were overweight, 8.18% had prehypertension, 16.45% had high blood glucose, and 11% children were malnourished. From the analysis of risk factors, we found that people aged > 40 were associated with developing hypertension, diabetes, and cardiovascular diseases(CVD). CVD was associated with hypertension and stroke. Comparative analysis of different periods showed improved BMI, BP, and MUAC. Blood glucose measurements did not show significant improvement.
Conclusion: The implemented model provided regular health screenings, consultancy services, and digital referrals. The features included in the model are unique and designed according to the needs of the rural population. Findings from the operation identified demographics who were at high risk of developing NCDs. The comparative analysis found a positive impact on the health conditions of the rural people who took regular health measurements.