bluuebunny/crossref_metadata_2025_split huggingface dataset:
Active and upcoming deals: effect on purchase intention
Authors: Chaklader Garima 
Published: October 2019

Purpose
The purpose of this paper is to study the interaction of timing cues (active deals vs upcoming deals) and brand familiarity on consumers’ purchase intention.

Design/methodology/approach
The research design of this paper is based on one experiment conducted in a behavioural experimental laboratory and two experiments in Mechanical Turk. The data received from these experiments were analysed using one-way ANOVA technique and PROCESS models.

Findings
Results across three experiments show that consumers prefer upcoming deals over active deals when brands are of low familiarity. However, the effect is attenuated for brands with high familiarity. Further, the paper proposes and shows that the effects of timing cues and brand familiarity interactions on purchase intention are explained by temporal distance. Finally, results show that need for cognition moderates the effects.

Research limitations/implications
The research results may vary when size of discounts is mentioned. There is a need to study various other moderators such as product type, self-other overlap and regulatory focus.

Practical implications
The paper offers managerial strategies and insights that can be adopted by the online retailing industry. Paper offers practical implications for brands, especially for ones with low familiarity.

Originality/value
This paper adds to the literature by studying new timing cues to understand the behaviour of consumers in retailing industries.
Unethical leader behavior and employee performance: a deontic justice perspective
Authors: Gan Chenjing , Guo Weixiao , Chai Yandong , Wang Duanxu 
Published: October 2019

Purpose
The purpose of this paper is to examine the mediating effect of deontic justice in the relationship between unethical leader behavior and employee performance, and whether leader–member exchange (LMX) moderates the effect.

Design/methodology/approach
A two-time-point questionnaire survey was used to collect data from 225 employees of nine firms in China at two points in time separated by approximately three weeks.

Findings
The hypothesized moderated mediation model used in this study was supported. Deontic justice mediates the negative relationship between unethical leader behavior and employee performance, and higher LMX tends to strengthen this indirect relationship.

Originality/value
Previous scholars mainly focused on the cognitive and conscious thought process to explain employees’ reactions to unethical leader behavior, and largely ignored the research on the nonconscious thought process. Drawing on deontic justice theory, this study extends the previous research on the nonconscious system of moral decision-making processing by introducing employee deontic justice as a mediator in the relationship between unethical leader behavior and employee performance and further exploring LMX as a boundary condition of this indirect relationship.
Developing the employee lifecycle to keep top talent
Authors: Cattermole Gary 
Published: October 2019

Purpose
This article aims to set out the best strategies to understand the employee life cycle and how to employ tactics to keep top talent within an organisation.

Design/methodology/approach
This feature explores desktop data and industry research.

Findings
This feature demonstrates how an employee’s life cycle can be extended in the workplace and explains the link between the employee value proposition and the employee life cycle to create successful onboarding strategies.

Social implications
This article also looks at how millennials will stay longer in an organisation that has strong environmental policies.

Originality/value
This feature offers fantastic insight into an issue that is currently costing the country millions.
How automation and digital disruption are shaping the workforce of the future
Authors: Card Debora , Nelson Craig 
Published: October 2019

Purpose
With the US unemployment rate at 50-year lows and the increased use of automation expected to force organizations to replace or retrain over 25 per cent of their workforce, enterprises need new ways to re-skill employees to prepare for future needs.

Design/methodology/approach
The authors spoke with HR leaders of different enterprises to see how they will adapt to the future of work with the combination of automation in the workplace. After gaining insights from multiple sources, they were able to come to some conclusions on how the future of work is shaping up to be.

Findings
After gaining insights, they were able to find that companies that seek to combine the best of human ingenuity, empathy and change resilience with the prudent use of automation and re-skilling will be leading the workforce of the future.

Originality/value
This paper from ISG was created to give insights into Strategic HR Review from real customers and research conducted. This paper gives valuable insights on how enterprises are actually re-skilling employees to adapt to the rise of automation and IT skills gap.
Unravelling plasmidome distribution and interaction with its hosting microbiome
Authors: Brown Kav Aya , Rozov Roye , Bogumil David , Sørensen Søren Johannes , Hansen Lars Hestbjerg , Benhar Itai , Halperin Eran , Shamir Ron , Mizrahi Itzhak 
Published: October 2019

SummaryHorizontal gene transfer via plasmids plays a pivotal role in microbial evolution. The forces that shape plasmidomes functionality and distribution in natural environments are insufficiently understood. Here, we present a comparative study of plasmidomes across adjacent microbial environments present in different individual rumen microbiomes. Our findings show that the rumen plasmidome displays enormous unknown functional potential currently unannotated in available databases. Nevertheless, this unknown functionality is conserved and shared with published rat gut plasmidome data. Moreover, the rumen plasmidome is highly diverse compared with the microbiome that hosts these plasmids, across both similar and different rumen habitats. Our analysis demonstrates that its structure is shaped more by stochasticity than selection. Nevertheless, the plasmidome is an active partner in its intricate relationship with the host microbiome with both interacting with and responding to their environment.
Forming Effective Employee Information and Consultation: A Five‐Stage Trust and Justice Process
Authors: Kougiannou Nadia K. , Dundon Tony , Wilkinson Adrian 
Published: October 2019

AbstractIn this paper we show how trust and justice influence the efficacy of employee information and consultation (I&C) bodies. Evidence is drawn from a 2‐year qualitative study of I&C participants in two organizations in the UK. The research builds on Dietz and Fortin's conceptual five‐stage model of the I&C process to provide a more nuanced understanding of I&C trust and justice outcomes. In particular, we point to crucial stages in the process, and how these influence the effectiveness of I&C mechanisms. Implications for theory and practice are discussed.
Brexit Means Brexit—or Does It? The Legacy of Theresa May's Discursive Treatment of Brexit
Authors: Brusenbauch Meislova Monika 
Published: October 2019

AbstractWith the looming reality of Brexit drawing closer, it is the intention of this article to explore Theresa May's post‐referendum communicative behaviour on Brexit—the very issue that came to define her premiership agenda—and uncover what legacy it has left behind. Building upon, extending and updating the emerging literature on May's discourse, the inquiry helps us understand how May acted through language in order to influence and change other people's attitudes towards and ways of looking at Brexit. The article argues that there are at least seven ways, closely interrelated and feeding into each other, in which her discursive construction of Brexit has left a somewhat bitter legacy, contributing to the Brexit political paralysis and inspiring substantial levels of confusion and exasperation, both within the UK and abroad.
In the Shadow of Brexit: The 2019 European Parliament Elections as First‐Order Polity Elections?
Authors: Galpin Charlotte , Trenz Hans‐Jörg 
Published: October 2019

AbstractEuropean Parliament (EP) elections have traditionally been described as ‘second‐order national elections' in which campaigns are fought by national parties on national issues. We argue that the 2019 elections should instead be considered ‘first‐order polity' elections. It is not EU‐level party politics or policy issues that are debated, but rather the legitimacy of the EU itself. Firstly, the EP elections have transformed into an EU ‘blame game' in which national governments are punished or rewarded over their stance on European integration. Secondly, the 2019 election was about the EU's fundamental values, not only with respect to multiculturalism, but also gender equality and LGBTQ rights. Finally, these first‐order polity elections are driven in large part by traditional news and social media platforms. While this is a long way from the patterns of the early EP elections, they still fail in fulfilling the function of holding MEPs and European party groupings adequately to account.
Changes in coding of pneumonia and impact on the Hospital Readmission Reduction Program
Authors: Buxbaum Jason D. , Lindenauer Peter K. , Cooke Colin R. , Nuliyalu Ushapoorna , Ryan Andrew M. 
Published: October 2019

AbstractObjectiveTo evaluate whether changes in diagnosis assignment explain reductions in 30‐day readmission for patients with pneumonia following the Hospital Readmission Reduction Program (HRRP).Data Sources100 percent MedPAR, 2008‐2015.Study DesignRetrospective cohort study of Medicare discharges in HRRP‐eligible hospitals. Outcomes were 30‐day readmission rates for pneumonia under a “narrow” definition (used for the HRRP until October 2015; n = 2 288 644) and a “broad” definition that included certain diagnoses of sepsis and aspiration pneumonia (used since October 2015; n = 3 618 215). We estimated changes in 30‐day readmissions in the pre‐HRRP period (January 2008‐March 2010), the HRRP implementation period (April 2010‐September 2012), and the HRRP penalty period (October 2012‐June 2015).Principal FindingsUnder the narrow definition, adjusted annual readmission rates changed by +0.07 percentage points (pp) during the pre‐HRRP period (95% CI: −0.03 pp, +0.18 pp), −1.07 pp during HRRP implementation (95% CI: −1.15 pp, −0.99 pp), and −0.09 pp during the penalty period (95% CI: −0.18 pp, −0.00 pp). Under the broad definition, 30‐day readmissions changed by +0.21 pp during the pre‐HRRP period (95% CI: +0.12 pp, +0.30 pp), −1.28 pp during HRRP implementation (95% CI: −1.35 pp, −1.21 pp), and −0.09 pp during the penalty period (95% CI: −0.16 pp, −0.02 pp).ConclusionsChanges in the coding of inpatient pneumonia admissions do not explain readmission reduction following the HRRP.
Statistical evidence and the problem of robust litigation
Authors: Bull Jesse , Watson Joel 
Published: October 2019

AbstractWe propose a new model of disclosure, interpretation, and management of hard evidence in the context of litigation and similar applications. A litigant has private information and may also possess hard evidence that can be disclosed to a fact‐finder, who interprets the evidence and decides a finding in the case. We identify conditions under which hard evidence generates value that is robust to the scope of rational reasoning and behavior. These fail if the litigant's private information is sufficiently strong relative to the “face‐value signal” of evidence, and then hard evidence may be misleading. Rules that exclude some relevant hard evidence can be justified.
Detection of EGFR gene mutation status from pleural effusions and other body fluid specimens in patients with lung adenocarcinoma
Authors: Zhang Ping , Wu Xiaonan , Tang Min , Nie Xin , Li Lin 
Published: October 2019

AbstractBackgroundEpidermal growth factor receptor (EGFR) gene mutation status is essential to the optimal management of lung adenocarcinoma. Liquid biopsy has advantages such as noninvasiveness, speediness, and convenience. This study aimed to detect EGFR gene mutations using next‐generation sequencing (NGS) from different types of body fluids from patients with lung adenocarcinoma.MethodsThis was a prospective study of 20 patients with lung adenocarcinoma recruited between January 2017 and December 2018 at the Beijing Hospital. All patients had adenocarcinoma with confirmed sensitizing EGFR mutations. Body fluid specimens included pleural effusion, ascites, pericardial effusion, and cerebrospinal fluid. NGS was conducted to test for nine lung cancer‐related gene in body fluid supernatant free DNA, sedimentary tumor cells, and plasma free DNA.ResultsThe EGFR gene mutation abundance of body fluid supernatant free DNA was higher than that of body fluid sedimentary tumor cells and plasma free DNA specimens (100% vs. 90% vs. 80%, respectively, all P < 0.05). The results of EGFR mutation from the body fluid supernatants were consistent with the results from the tissue biopsy.ConclusionsThis study showed that compared with body fluid sediment tumor cells and plasma free DNA samples, body fluid supernatant free DNA has a higher detection rate and sensitivity of tumor‐specific mutations. Free DNA obtained from body fluid supernatants could be used as high‐quality specimens for gene mutation detection in patients with lung cancer. This could be applied in treatment decisions and patient management.
Intraocular pressure response affected by changing of sitting and supine positions
Authors: Najmanová Eliška , Pluháček František , Haklová Markéta 
Published: October 2019

AbstractPurposeTo assess the intraocular pressure (IOP) time response to change in body position from sitting to supine and from supine to sitting immediately and during rest in each position.MethodsForty‐four visually healthy volunteers were recruited for the study. The experiment consisted of the initial sitting position (baseline state), the subsequent lying period and the final sitting period. Both periods were 30 min long. The IOP was measured in the baseline state, immediately after each position change and then in minutes 5, 15, 25 and 30 during each period. The Icare Pro® rebound tonometer was used.ResultsThe mean IOP increased after each position change (2.6 ± 2.4 mmHg after lying down and 2.1 ± 3.1 mmHg after sitting up) and then gradually decreased with time. The mean IOP was 1.41 ± 2.4 mmHg higher in the lying period than in the sitting period; the mean difference was smaller for the lower baseline (0.9 ± 2.2 mmHg) than the higher baseline (1.9 ± 2.5 mmHg). The mean IOP in the final sitting was significantly lower (2.5 ± 1.9 mmHg) than in the initial sitting position. The effect of sex was insignificant.ConclusionsThere was an immediate increase in IOP as a response to both changes in the body position and the subsequent gradual decrease with time. The IOP difference between lying and sitting position was depended on baseline.
Diminished social interaction incentive contributes to social deficits in mouse models of autism spectrum disorder
Authors: Rein Benjamin , Yan Zhen , Wang Zi‐Jun 
Published: October 2019

AbstractOne of the core symptoms of autism spectrum disorder (ASD) is impaired social interaction. Currently, no pharmacotherapies exist for this symptom due to complex biological underpinnings and distinct genetic models which fail to represent the broad disease spectrum. One convincing hypothesis explaining social deficits in human ASD patients is amotivation, however it is unknown whether mouse models of ASD represent this condition. Here we used two highly trusted ASD mouse models (male Shank3‐deficient [Shank3+/ΔC] mice modeling the monogenic etiology of ASD, and inbred BTBR mice [both male and female] modeling the idiopathic and highly polygenic pathology for ASD) to evaluate the level of motivation to engage in a social interaction. In the behavioral paradigms utilized, a social stimulus was placed in the open arm of the elevated plus maze (EPM), or the light compartment of the light‐dark box (LDB). To engage in a social interaction, mice were thus required to endure innately aversive conditions (open areas, height, and/or light). In the modified EPM paradigm, both Shank3+/ΔC and BTBR mice demonstrated decreased open‐arm engagement with a social stimulus but not a novel object, suggesting reduced incentive to engage in a social interaction in these models. However, these deficits were not expressed under the less severe aversive pressures of the LDB. Collectively, we show that ASD mouse models exhibit diminished social interaction incentive, and provide a new investigation strategy facilitating the study of the neurobiological mechanisms underlying social reward and motivation deficits in neuropsychiatric disorders.
Pathogenesis of Cluster Headache: From Episodic to Chronic Form, the Role of Neurotransmitters and Neuromodulators
Authors: D'Andrea Giovanni , Gucciardi Antonina , Perini Francesco , Leon Alberta 
Published: October 2019

ObjectiveTo describe the role of biochemical anomalies of tyrosine (TYR), tryptophan (TRP), and arginine (ARG) metabolism in patients suffering from episodic and chronic cluster headache (CCH).BackgroundThe pathogenesis of cluster headache (CH) and the process that transforms the episodic into the chronic form are unknown. However, the accompanying symptoms suggest a dysfunction of the sympathetic system and hypothalamus along with anomalies of metabolism of catecholamines, elusive amines, and nitric oxide (NO) metabolism.MethodsWe describe the results obtained from the last papers published on this issue. The level of metabolites were analyzed by different high‐performance liquid chromatography methods.ResultsIn both episodic and CH patients, the levels of dopamine and elusive amines are very elevated. The only biochemical difference found in studies between episodic and chronic cluster was that norepinephrine levels were significantly lower in episodic cluster in comparison to control and chronic subjects. In addition, the levels of ARG, homoarginine, and citrulline, precursors of synthesis of NO, were significantly lower in chronic cluster.ConclusionsAll these results suggest that TYR, TRP, and ARG metabolism is abnormal and may constitute a biochemical fingerprint of CH patients. The increased levels of norepinephrine in chronic cluster constitute a possible cause of chronicity of this primary headache. The high levels of tryptamine and its activity on the central serotoninergic system may explain why the length of CH is brief in comparison to migraine and tension‐type headache. The low levels of ARG, homoarginine, and citrulline may be the consequence of high circulating levels of α1‐agonists, such as epinephrine and norepinephrine, and their biochemical interaction with endothelial trace amine‐associated receptor 1 that induces activation of NO synthase, resulting in NO synthesis in the circulation, NO release, intense vasodilation, and as a result, the cluster attack.
Teaching information literacy skills to medical students: perceptions of health sciences librarians
Authors: Ullah Midrar , Ameen Kanwal 
Published: October 2019

AbstractBackgroundThis paper is the second part of a two phase, sequential mixed method study.ObjectivesTo get the views of medical librarians in Pakistan regarding information literacy (IL) skills of medical students and how to teach them IL skills.MethodsStructured interviews were conducted with 20 medical librarians in Pakistan. We audio recorded, transcribed all the interviews and performed content analysis and coding of the textual data. We presented the emerging themes with the frequency of their appearance.ResultsInterviewees agreed that the IL skills of their students were inadequate. Participants suggested that librarians should train students through mandatory IL instruction programmes, designed in coordination with medical faculty. However, workshops/seminars were considered the most effective IL delivery methods for medical faculty and clinicians. The majority of respondents supported the integration of IL instruction into the curriculum as an independent and credit course.DiscussionTeaching IL skills to medical students requires proper planning. Therefore, librarians have to prove their place within the curricular structure of the institution and develop understanding of the pedagogy of instruction.ConclusionLibrarians must collaborate with faculty to train students in advanced information skills. There is a need to integrate IL instruction into the curriculum at all levels.
Post‐exposure prophylaxis for HIV infection in sexual assault victims
Authors: Inciarte A , Leal L , Masfarre L , Gonzalez E , Diaz‐Brito V , Lucero C , Garcia‐Pindado J , León A , García F ,   the Sexual Assault Victims Study Group
Published: October 2019

ObjectivesSexual assault (SA) is recognized as a public health problem of epidemic proportions. Guidelines recommend the administration of post‐exposure prophylaxis (PEP) after an SA. However, few data are available about the feasibility of this strategy, and this study was conducted to assess this.MethodsWe conducted a retrospective, longitudinal, observational study in SA victims attending the Hospital Clinic in Barcelona from 2006 to 2015. A total of 1695 SA victims attended the emergency room (ER), of whom 883 met the PEP criteria. Five follow‐up visits were scheduled at days 1, 10, 28, 90 and 180 in the out‐patient clinic. The primary endpoint was PEP completion rate at day 28. Secondary endpoints were loss to follow‐up, treatment discontinuation, occurrence of adverse events (AEs) and rate of seroconversion.ResultsThe median age of participants was 25 years [interquartile range (IQR) 21–33 years] and 93% were female. The median interval between exposure and presentation at the ER was 13 h (IQR 6–24 h). The level of risk was appreciable in 47% (n = 466) of individuals. Of 883 patients receiving PEP, 631 lived in Catalonia. In this group, the PEP completion rate at day 28 was 29% (n = 183). The follow‐up rate was 63% (n = 400) and 38% (n = 241) at days 1 and 28, respectively. Treatment discontinuation was present in 58 (15%) of 400 patients who attended at least the day 1 visit, the main reason being AEs (n = 35; 60%). AEs were reported in 226 (56%) patients, and were mainly gastrointestinal (n = 196; 49%). Only 211 (33%) patients returned for HIV testing at day 90. A single seroconversion was observed in a men who have sex with men (MSM) patient at day 120.ConclusionsFollow‐up and compliance rates in SA victims were poor. In addition, > 50% of the patients experienced AEs, which were the main reason for PEP interruption. Strategies to increase follow‐up testing and new better tolerated drug regimens must be investigated to address these issues.
Results of a survey of cancer patients’ willingness to travel to participate in a clinical trial
Authors: Zdenkowski Nicholas , Lynam James , Sproule Victoria , Wall Laura , Searston Jessica , Brown Scott 
Published: October 2019

AbstractOnly 2–3% of cancer patients enrol in a trial. We surveyed patients' willingness to change clinician or treating centre, or to travel, to participate in trials, to improve trial recruitment. Of 188 respondents, 79% were willing to participate in a trial in at least one scenario. Increasing travel time, change in oncologist, private health insurance and out of pocket expenses decreased likelihood of joining a trial. Rural and regional patients, and those from lower socio‐economic areas, were more willing to travel. To optimise access to trials, clinicians should refer within and between institutions.