bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified prophylactic 5‐fr pancreatic duct stent enhances the rate of spontaneous dislodgement: A multicenter randomized controlled trial
Authors: He Qibin , Wang Lei , Peng Chunyan , Zou Xiaoping , Zhan Qiang , Xu Yaping , Liu Qiang , Qian Junbo , Gong Lei , Shen Yingzhou , Chen Jianping 
Published: October 2018

Background and objectivesProphylactic pancreatic duct stent placement effectively reduces post‐endoscopic retrograde cholangiopancreatography pancreatitis in high‐risk patients, but the optimal stent remains unclear. We modified a 5‐Fr, 3 cm pancreatic stent by removing the flange on the pancreatic side and compared the rate of spontaneous dislodgement and complications with the ordinary stent.MethodsThis was a randomized controlled trial at six tertiary endoscopic centers. Patients deemed high risk for post‐endoscopic retrograde cholangiopancreatography pancreatitis randomly received modified or ordinary pancreatic stent. The primary outcome was spontaneous stent dislodgement at five days and 14 days. Secondary outcomes were the success rate of stent placement and complications.ResultsA total of 276 patients were randomly assigned to receive modified stents (mS group) and ordinary stents (oS group). The placement of a pancreatic stent was successful in all 276 patients. There were no significant differences between groups with respect to age, sex, major diagnosis, or indications for stenting. At five days the spontaneous dislodgement rate was 47.72% for the mS group and 15.67% for the oS group (p<0.001); at 14 days the rates were 84.21% and 42.65%, respectively (p < 0.001). Post‐endoscopic retrograde cholangiopancreatography pancreatitis occurred in 6.52% of all patients. There were no significant differences regarding the incidences of post‐endoscopic retrograde cholangiopancreatography pancreatitis, hemorrhage or fever.ConclusionsThe modified short 5‐Fr stent has a higher spontaneous dislodgement rate than ordinary pancreatic stent, thus obviating the need for endoscopic removal. The modified pancreatic stent does not increase the incidence of post‐endoscopic retrograde cholangiopancreatography pancreatitis or other complications. The endoscopist can consider removing the flange on the pancreatic duct side for prophylactic pancreatic duct manipulation.
The clinical approach to managing herpes simplex virus encephalitis
Authors: Leahy Christopher B , Mathur Sachin , Majeed Tahir 
Published: October 2018

This article explains the approach to managing a patient with herpes simplex virus encephalitis. Acute encephalopathy is a common and often intimidating presentation in an acute general medical setting. Application of key principles will enable the generalist to take life-saving action before obtaining any specialist input. Viral infection is the most common cause (48.2%) of encephalitis; another large group is cases of autoimmune aetiology. Early diagnosis of encephalitis is crucial to ensure that the right treatment is given on time. Guidelines on the management of viral encephalitis were published by the British Association of Neurologists and British Infection Association ( Solomon et al, 2012 ), but adherence to these standards by clinicians has been found to be suboptimal ( Han and Coebergh, 2017 ). This puts lives in danger, in the context of a treatable, serious, acute presentation. Although viral infection is the most common cause of encephalitis, an awareness of rarer forms of autoimmune encephalitis is necessary. The differential diagnosis of autoimmune encephalitis is important because the disease is potentially treatable with immunosuppressive agents. Paraneoplastic limbic encephalitis may present months or years before the detection of a tumour.
Acute medical problems in pregnancy
Authors: Coad Felicity , Nelson-Piercy Catherine 
Published: October 2018

The maternal population in the UK has become an increasingly challenging group of patients to manage. Women with pre-existing and often complex medical conditions are successfully conceiving. Most physicians will have had some involvement in the care of obstetric patients admitted with medical problems, and a lack of experience and fear of causing harm may result in essential investigations and treatment being withheld. The physiological changes in pregnancy can complicate the interpretation of observations and test results. This article discusses the presentation of commonly encountered medical problems in the obstetric population, including breathlessness, chest pain, palpitations, seizure and headache. It covers specific investigations and suggested treatment in this subset of patients. These women should receive the same level of care and attention as those who are not pregnant. Early diagnosis and effective management can help to reduce maternal morbidity and mortality caused by medical problems arising during pregnancy.
Improvement of Soil Physical Properties of Cambisol Using Soil Amendment
Authors: Darusman Darusman , Devianti Devianti , Husen Edi 
Published: October 2018

Managing dryland requires intergrated knowledges on soil, water and plants relationship in order to achieve maximum yield. Using local and unused resource is important not only in aspect of reducing pollution but low price and also affordable for farmers. Thus, using amendment from in situ resources is suggested by many experts. This amendment used is assumed it could contribute improvement physical properties of soil and result better yields. This study aimed to studi more deeply on how much of soil amendment might improve physical properties of Cambisol under dryland environment and furthermore find out the crop response to soil amendments. The research was conducted during July to Oct. 2016 at Gampong Paud, Muara Tiga District, Pidie District, Aceh Province with the altitude ± 30 m asl and slope 0-3 %. A Randomized Completely Block Design (RCBD) with two factors replicated three times was used. First factor was soil amendment consisting of 4 levels ; no amendment (control), cow manure amount 10 ton ha -1, straw compost 10 ton ha-1, and cow manure 10 ton ha -1 + compost 10 ton ha-1. The second factor was 5 varieties of peanut: Tuban, Hypoma 2, Bima, Kelinci and Gajah. The parameters observed were soil bulk density, permeability, total soil porosity, aggregate stability index, soil water holding capacity at water potential -3 and -15 bar. Results of our studies showed soil amandement improves some soil physical properties, combination amendment with variety of peanuts resulted significant effects to soil physical properties, and combination treatments mostly influenced soil physical properties at soil depth of 0 -20 cm. Addition of 10 tons ha -1 cow manure or 10 ton ha -1 straw compost is enough to improve soil physical properties
Measuring Passenger Car Unit (PCU) at Four Legged Roundabout using Time Occupancy Data Collected from Drone
Authors: Sugiarto Sugiarto , Apriandy Fadhlullah , Faisal Ruhdi , Saleh Sofyan M. 
Published: October 2018

This study aims to measure the values of passenger car unit (PCU) at a four-legged roundabout based on the time occupancy data in complex traffic operation. Within mixed traffic, the PCUs are needed as a equivalency factor to convert various type of vehicles to a standard unit. The unit of PCU was used to determine capacity and level of service of specific the traffic condition. The composition of vehicles going through the intersection, mostly varies and each type of vehicles tends to have diverse effects on capacity and level of services. Consequently, a conversion factor from various vehicles to a standard vehicle is required. The data of this study was collected using a drone at the investigated roundabout at one of the major roundabouts in Aceh Besar, Aceh province, Indonesia. The method used was the vehicle's time occupancy, in which calculated from the average time required by each vehicle to pass through the roundabout area. The results show that the PCU values obtained is 0.16 for motorcycle, 0.59 for rickshaw, 1.07 for pickup, 1.91 for a medium vehicle, and 3.76 for the heavy vehicle. These results should be utilized for converting various type of vehicles into PCUs to estimate capacity and level of services, especially at the roundabout trafict. This results may be suitable to revise the Indonesian Traffic Code, named Indonesian Highway Capacity Manual 1997, and useful for ongoing national-level efforts to upgrade the Indonesian Highway Capacity Manual.
Characterization of Rare Earth Elements in Tailing of Ex-Tin Mining Sands from Singkep Island, Indonesia
Authors: Hamzah Yanuar , Mardhiansyah Muhammad , Firdaus Liong Nyuk 
Published: October 2018

The objective of this research is to determine the rare earth elements (REEs) from themonazite minerals content of several tin tailing sands (TTS)of ex-tin mining area in Kuala Raya Singkep Island, Indonesia. We used the energy dispersive analysis of X-ray (EDAX)-scanning electron microscopy (SEM) and x-ray diffraction (XRD) to characterize the contents of the samples. The coupled analytical of XRD with SEM/EDX approach enabled to be used for mineralogical identification on the heavy mineral as a rapid determination approach. The analysis of the samples indicates only the presence of REEs including lanthanum (La), cerium (Ce), and thorium (Th) are consistent with the identification of monazite and minerals in the tailing sand. The results show that the average REEs consist of La at 0.2 .%, Ce at 7.8 %, and Th at 2.0% respectively. It is concluded that monazite minerals in TTS has an economic potential to be developed. These monazite minerals can be used as material for semiconductor devices.
Examination of the life quality of lecturer of Sports Science Faculties according to various variables <p>Spor Bilimleri Fakültesinde görev yapan öğretim elemanlarının yaşam kalitelerinin çeşitli değişkenlere göre incelenmesi
Authors: Çalık Fehmi , Okudan Bilal , Mikailsoy Günel , Keten Seyyit Ahmet 
Published: October 2018

The purpose of this study is to investigate the life quality of lecturers working in the Sports Science Faculty according to some factors. For this purpose, a 27-items short form of WHOQOL-BREF Quality of Life scale and Personal Information Form was applied to the 101 (female 36, male 65) lecturers of sport sciences faculties in the Marmara region on a voluntary. The SPSS package program was used for statistical analysis. For the normality of data, Skewness and Kurtosis points were checked. For the normal distribution, One-way ANOVA Pearson correlation were used for the analysis of data.According to findings, while there was no significant difference between the quality of life subscales and gender, age and monthly income level, there was a significant difference between the participate to sports activities. It was also found that there was a positive correlation between quality of life subscales.As a result, it was found that the participating to sports activities caused significant differences in the quality of life.Extended English summary is in the end of Full Text PDF (TURKISH) file. ÖzetBu araştırmanın amacı, spor bilimleri fakültelerinde görev yapan öğretim elemanlarının yaşam kalitelerini bazı değişkenlere göre incelemektir. Bu amaçla Marmara Bölgesi’ndeki spor bilimleri fakültelerinde çalışan 101 (36 kadın, 65 erkek) öğretim elemanlarının bazılarına yüz yüze bazılarına internet üzerinden gönüllü olarak 27 sorudan oluşan WHOQOL-BREF Yaşam Kalitesi Ölçeği kısa formu ve Kişisel Bilgi Formu uygulanmıştır. Verilerin analizinde SPSS paket programı kullanılmıştır. Verilerin normalliği için skewness ve kurtosis değerleri control edilmiştir. Normal dağılım gösteren veriler için, independent t test, One-way ANOVA ve korelasyon analizi kullanılmıştır.Bulgulara göre, yaşam kalitesi alt boyutları ile cinsiyet, yaş ve aylık gelir düzeyi arasında anlamlı bir farklılık görülmezken, spor yapma durumu arasında anlamlı bir farklılık görülmüştür. Ayrıca, yaşam kalitesi alt boyutları arasında pozitif yönlü bir ilişki olduğu tespit edilmiştir.Sonuç olarak, spor yapma durumunun yaşam kalitesi üzerinde önemli farklılıklara neden olduğu görülmüştür.
The conveyance of Andalusian music culture to Medieval Europe through Qiyan Girls<p>Endülüs müzik kültürünün Qiyan Kızları aracılığı ile Ortaçağ Avrupasına aktarımı
Authors: Erdal Gülşen 
Published: October 2018

In this study, cultural influences of Andalusian music on medieval Europe was attempted to be assessed. In Andalusia, music was institutionalized in the field of education within the musical identity of the musician Ziryab from Baghdad. It was seen that the techniques and methods used in this school now take part in "conservatory" education. It was determined that some of the instruments used today are of Andalusian origin and were transferred to medieval Europe through cultural interactions. It was seen that the forms of singing move to Europe with examples of minstrels and religious music in both religious and secular areas of music. It was determined that this situation emerged as a result of the interaction of the common music culture of the cultures living in Andalusia with medieval Europe. The data were obtained by literature review.Extended English summary is in the end of Full Text PDF (TURKISH) file. ÖzetBu çalışmada, Endülüs Müziği’nin Ortaçağ Avrupası’na kültürel etkileri değerlendirilmeye çalışılmıştır. Endülüs’de müziğin, Bağdat’lı müzisyen Ziryab’ın müzikal kimliğinde, eğitim alanında kurumsallaştığı tespit edilmiştir. Bu okulda kullanılan teknik ve yöntemlerin, günümüzde konservatuvar eğitiminde yer aldığı görülmüştür. Günümüzde kullanılan bazı çalgıların Endülüs kaynaklı olduğu ve ortaçağ Avrupa’sına kültürel etkileşimler yoluyla geçtiği belirlenmiştir. Şarkı söyleme biçimlerinin hem dini hem dindışı müzik alanlarında saz şairleri ve dinsel müzik örnekleriyle Avrupa’ya taşındığı görülmüştür. Bu durumun Endülüs’de yaşayan kültürlerin ortak müzik kültürünün Ortaçağ Avrupası’yla etkileşimi sonucu ortaya çıktığı belirlenmiştir. Çalışmada veriler literatür tarama yöntemiyle elde edilmiştir.
Microbial transglutaminase for biotechnological and biomedical engineering
Authors: Deweid Lukas , Avrutina Olga , Kolmar Harald 
Published: October 2018

Abstract
Research on bacterial transglutaminase dates back to 1989, when the enzyme has been isolated from Streptomyces mobaraensis. Initially discovered during an extensive screening campaign to reduce costs in food manufacturing, it quickly appeared as a robust and versatile tool for biotechnological and pharmaceutical applications due to its excellent activity and simple handling. While pioneering attempts to make use of its extraordinary cross-linking ability resulted in heterogeneous polymers, currently it is applied to site-specifically ligate diverse biomolecules yielding precisely modified hybrid constructs comprising two or more components. This review covers the extensive and rapidly growing field of microbial transglutaminase-mediated bioconjugation with the focus on pharmaceutical research. In addition, engineering of the enzyme by directed evolution and rational design is highlighted. Moreover, cumbersome drawbacks of this technique mainly caused by the enzyme’s substrate indiscrimination are discussed as well as the ways to bypass these limitations.
Impact of Activation Energy in Nonlinear Mixed Convective Chemically Reactive Flow of Third Grade Nanomaterial by a Rotating Disk
Authors: Hayat T. , Khan Sohail A. , Khan M. Ijaz , Alsaedi A. 
Published: October 2018

Abstract
Here impact of activation energy in binary chemically reactive flow of third grade fluid is addressed. Flow is discussed by a stretchable rotating disk. Novel characteristics regarding thermophoresis and Brownian movement have been analyzed. Nonlinear thermal radiation is considered. Convergent series solutions to nonlinear problems are computed. Impacts of various physical parameters like Brownian motion parameter, Prandtl number, mixed convection parameter, thermophoresis parameter, radiation parameter, activation energy, chemical reaction and Schmidt number on the velocity, concentration and thermal fields are discussed and analyzed. Velocity, temperature and concentration gradients are computed and discussed through various flow variables. Their obtained results present that velocity, temperature, concentration fields are strongly depends on the flow parameters. Main conclusions are presented.
High Expression of NLRC5 is associated with prognosis of gastric cancer
Authors: Li Yuemei , Zhang Min , Zheng Xinhua 
Published: October 2018

Abstract

Objective
To explore the relationships of NLRC5 with clinicopathological characteristics and prognosis of gastric cancer patients.

Methods
A total of 97 gastric cancer patients undergoing radical gastrectomy were enrolled. All patients were diagnosed by immunohistochemical staining. The relationship between NLRC5 expression and clinicopatho-logical characteristics of gastric cancer was analyzed via univariate and multivariate Cox regressions.

Results
NLRC5 expression was positive in 70 cases (72.2%) and negative in 27 cases (27.8%). No significant differences in age, sex, or tumor size or differentiation were found between the negative and positive groups. NLRC5 expression was related to tumor site, and in the positive group, it was high in the fundus and low in the pylorus (χ2=7.359, P=0.125). NLRC5 expression was significantly related to lymph nodes and tumor node metastasis (TNM) staging (χ2=6.295; χ2=6.268). Multivariate Cox regression indicated positive NLRC5 expression was independently and significantly associated with prognosis of gastric cancer patients (HR=2.92, 95%CI: 1.51-5.63).

Conclusions
NLRC5 is closely related to TNM staging and lymph node metastasis of gastric cancer and is an independent risk factor for the prognosis of gastric cancer patients.
Is monitoring mean platelet volume necessary in breast cancer patients?
Authors: Taskaynatan Halil , Alacacioglu Ahmet , Kucukzeybek Yuksel , Varol Umut , Yildiz Yasar , Salman Tarik , Oflazoglu Utku , Tarhan Mustafa Oktay 
Published: October 2018

Abstract

Background
Mean platelet volume (MPV) is a parameter that increases during thrombotic and cardiovascular events. Tamoxifen (Tmx) and aromatase inhibitors (AIs), which are adjuvant endocrine therapies, may cause serious side effects, such as vascular thrombosis. The present study investigated the changes in MPV values of breast cancer patients receiving long-term adjuvant hormone therapy and the relationship of MPV with adverse effects of hormonotherapy.

Methods
Data of 261 patients who had pathologically confirmed estrogen or progesterone receptor positive invasive breast cancer and had received hormonotherapy for at least a 5-year period were retrospectively analyzed. MPV levels were measured at baseline and at the first and fifth year of hormone therapy.

Results
All patients were females and their median age was 50 years (range, 27–78 years). The mean MPV value was significantly increased in all patients in the Tmx, AI, and switch groups over time (p<0.001).

Conclusion
This is the first study evaluating the relationship between the 5-year adjuvant endocrine therapy and changes in MPV values in breast cancer patients. Monitoring changes in MPV values may be predictive for severe side effects in breast cancer patients receiving hormone therapy.
Glancing angle deposition meets colloidal lithography: a new evolution in the design of nanostructures
Authors: Ai Bin , Zhao Yiping 
Published: October 2018

Abstract
The combination of colloidal lithography and glancing angle deposition facilitates a new powerful fabrication technique – shadow sphere lithography (SSL), which can greatly expand the variety and complexity of nanostructures fabricated using simple evaporation and colloidal monolayer templates. Their applications have been widely investigated in plasmonics and associated fields. Here, we present an overview of the principle of SSL, followed by different strategies of utilizing SSL to design various nanostructures by changing the nanosphere monolayer masks, deposition configurations, different ways to combine deposition and etching, etc. Typical nanostructures fabricated by SSL, including nanorods on nanospheres, patchy nanospheres, nanotriangles, nanoring, nanocrescents, etc., are introduced. Recent optical applications of these plasmonic nanostructures are also summarized. It is expected that this review will inspire more ingenious designs of plasmonic nanostructures by SSL for advanced and smart applications.
Crystal structure of bis(6,6′-((ethane-1,2-diylbis(azanylylidene))bis(methanylylidene))bis(2,4-diiodophenolato)-κ4
N,N′,O,O′)cer(IV), C32H20CeI8N4O4
Authors: Wu Qiong , Tang Yafang , Liu Dian , Zi Qiaoli , Liu Faxi , Xiao Jianchang 
Published: October 2018

Abstract
C32H20CeI8N4O4, tetragonal, P4̄b2 (no. 117), a = 11.1898(8) Å, b = 11.1898(8) Å, c = 16.6870(19) Å, V = 2089.4(4) Å3, Z = 2; R
gt(F) = 0.0566, wR
ref(F
2) = 0.0939, T = 293(2) K.
Crystal structural of diethyl 4-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, C19H21Br2NO5
Authors: Zheng Feng , Quan Ji-Shu , Cui Xiang-Dan , Jin Xue-Feng , Yin Xue-Zhe 
Published: October 2018

Abstract
C19H21Br2NO5, monoclinic, P21/c (no. 14), a = 8.657(5) Å, b = 17.150(5) Å, c = 13.889(4) Å, β = 104.807(15)°, V = 1993.6(14) Å3, Z = 4, R
gt(F) = 0.0646, wR
ref(F
2) = 0.1732, T = 293(2) K.
The crystal structure of 2,6-dimethyl-3,5-dinitrocyclohexa-2,5-diene-1,4-dione, C8H6N2O6
Authors: Fanfan Shen , Jianlong Wang , Shaomin Xue 
Published: October 2018

Abstract
C8H6N2O6, orthorhombic, Pnma (no. 62), a = 6.4261(7) Å, b = 17.080(2) Å, c = 8.5393(10) Å, V = 937.2(2) Å3, Z = 4, R
gt(F) = 0.0444, wR
ref(F
2) = 0.0977, T = 173(2) K.
Influence of climate and environmental change in Nigeria: a review on vulnerability and adaptation to climate change
Authors: Odey Emmanuel Alepu , Abo Bodjui Olivier , Li Zifu , Zhou Xiaoqin , Giwa Abdulmoseen Segun 
Published: October 2018

Abstract
This paper reviews the current issues that involve environmental changes in Nigeria and environmental threats within the country. The fundamental aim of scientific knowledge in environmental studies is to reconcile climate change and environmental sustainability with developmental goals. Therefore, information on impact adaptation to climate change and vulnerability research is required to develop specific, action-oriented, interdisciplinary, successful, sociopolitical and democratic reform for the entire population of a country. This condition requires large inclusion of environmental researchers, institutions, re-inventing of research structures and ideas to dominate the global environmental change research and the critical analysis of present decision making, power, structure and related information structures. This review presents the effect of climate change in Nigeria and encourages adaptation research with challenging innovation, such as the use of energy-efficient renewable energy sources to significantly reduce greenhouse gas emissions. This paper also highlighted the need for researchers to become detailed, action oriented and multiscalar and to attend communications structure problems in enhancing the environmental activity.