bluuebunny/crossref_metadata_2025_split huggingface dataset:
Técnica de Imaginación Guiada en el manejo de la ansiedad materna durante el embarazo: revisión integradora
Authors: Furtado Ana Rute , Gonçalves Machado Patrícia Maria , Fernandes Carneiro Marinha Nascimento 
Published: January 2019

Este artigo descreve a importância da Técnica de Imaginação Guiada na gestão da ansiedade materna durante a gravidez.Objetivo: Conhecer a evidência científica sobre a influência da Técnica de Imaginação Guiada na gestão da ansiedade materna durante a gravidez.Método: Revisão integrativa da literatura realizada na base de dados The Cochrane Library e através da plataforma EBSCO Host. De um total de 30 artigos obtidos, foram incluídos no estudo 10 artigos.Resultados/Discussão: Da análise da evidência científica resultaram as seguintes temáticas: ansiedade, gestão do stress e impacto fisiológico; relaxamento e bem-estar; adesão à Técnica de Imaginação Guiada; perceção positiva da gravidez; dificuldades na sua utilização.Conclusão: A Técnica de Imaginação Guiada parece promover o relaxamento e bem-estar da mulher, assim como diminuir os níveis de ansiedade e desconfortos percecionados durante a gravidez.
Este artículo describe la importancia de la Técnica de Imaginacion Guiada en el manejo de la andiedad materna durante el embarazo.Objetivos: Conocer la evidencia científica sobre la influencia de la Técnica de Imaginacion Guiada en el manejo de la ansiedad materna durante el embarazo.Metodologia: Revisión integradora de la literatura realizada en la base de datos The Cochrane Library y en la plataforma EBSCO Host. Se obtuvieron 30 artículos, de los cuales se incluyeron 10 artículos en el estudio.Resultados/Discusión: Del análisis de la evidencia científica resultaron los siguientes temas: ansiedad; manejo del estrés y su impacto fisiológico; relajación y bienestar; adhesión a la Técnica de Imaginacion Guiada; percepción positiva del embarazo; dificultades en el uso de la Técnica de Imaginacion Guiada. Conclusión: La Técnica de Imaginacion Guiada parece promover la relajación y el bienestar de las mujeres, así como los niveles más bajos de ansiedad y de malestar percibidos durante el embarazo.
Summary: This article describes the importance of the Guided Imagery Technique for the management of maternity associated anxiety during pregnancy. Goal: To understand the scientific evidence regarding the Guided Imagery Technique for the management of maternity associated anxiety during pregnancy. Method: Integrative revision of the literature from the Cochrane Library database, using the platform EBSCO Host. From a total of 30 articles on the subject, 10 were included on this articleResults/Discussion: The scientific evidence analysis translates on the following topics: anxiety, stress management and physiological impact; relaxation and well-being; adherence to the Guided Imagery Technique; positive perception of the pregnancy; difficulties to its use. Conclusion: The Guided Imagery Technique seems to promote the relaxation and well being of the women and also, aids with the reduction of anxiety levels and perceived discomfort during pregnancy
High-molecular-weight polymers from dietary fiber drive aggregation of particulates in the murine small intestine
Authors: Preska Steinberg Asher , Datta Sujit S , Naragon Thomas , Rolando Justin C , Bogatyrev Said R , Ismagilov Rustem F 
Published: January 2019

The lumen of the small intestine (SI) is filled with particulates: microbes, therapeutic particles, and food granules. The structure of this particulate suspension could impact uptake of drugs and nutrients and the function of microorganisms; however, little is understood about how this suspension is re-structured as it transits the gut. Here, we demonstrate that particles spontaneously aggregate in SI luminal fluid ex vivo. We find that mucins and immunoglobulins are not required for aggregation. Instead, aggregation can be controlled using polymers from dietary fiber in a manner that is qualitatively consistent with polymer-induced depletion interactions, which do not require specific chemical interactions. Furthermore, we find that aggregation is tunable; by feeding mice dietary fibers of different molecular weights, we can control aggregation in SI luminal fluid. This work suggests that the molecular weight and concentration of dietary polymers play an underappreciated role in shaping the physicochemical environment of the gut.Editorial note: This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (<xref ref-type="decision-letter" rid="SA1">see decision letter</xref>).
Gut microbiota density influences host physiology and is shaped by host and microbial factors
Authors: Contijoch Eduardo J , Britton Graham J , Yang Chao , Mogno Ilaria , Li Zhihua , Ng Ruby , Llewellyn Sean R , Hira Sheela , Johnson Crystal , Rabinowitz Keren M , Barkan Revital , Dotan Iris , Hirten Robert P , Fu Shih-Chen , Luo Yuying , Yang Nancy , Luong Tramy , Labrias Philippe R , Lira Sergio , Peter Inga , Grinspan Ari , Clemente Jose C , Kosoy Roman , Kim-Schulze Seunghee , Qin Xiaochen , Castillo Anabella , Hurley Amanda , Atreja Ashish , Rogers Jason , Fasihuddin Farah , Saliaj Merjona , Nolan Amy , Reyes-Mercedes Pamela , Rodriguez Carina , Aly Sarah , Santa-Cruz Kenneth , Peters Lauren , Suárez-Fariñas Mayte , Huang Ruiqi , Hao Ke , Zhu Jun , Zhang Bin , Losic Bojan , Irizar Haritz , Song Won-Min , Di Narzo Antonio , Wang Wenhui , Cohen Benjamin L , DiMaio Christopher , Greenwald David , Itzkowitz Steven , Lucas Aimee , Marion James , Maser Elana , Ungaro Ryan , Naymagon Steven , Novak Joshua , Shah Brijen , Ullman Thomas , Rubin Peter , George James , Legnani Peter , Telesco Shannon E , Friedman Joshua R , Brodmerkel Carrie , Plevy Scott , Cho Judy H , Colombel Jean-Frederic , Schadt Eric E , Argmann Carmen , Dubinsky Marla , Kasarskis Andrew , Sands Bruce , Faith Jeremiah J 
Published: January 2019

To identify factors that regulate gut microbiota density and the impact of varied microbiota density on health, we assayed this fundamental ecosystem property in fecal samples across mammals, human disease, and therapeutic interventions. Physiologic features of the host (carrying capacity) and the fitness of the gut microbiota shape microbiota density. Therapeutic manipulation of microbiota density in mice altered host metabolic and immune homeostasis. In humans, gut microbiota density was reduced in Crohn’s disease, ulcerative colitis, and ileal pouch-anal anastomosis. The gut microbiota in recurrent Clostridium difficile infection had lower density and reduced fitness that were restored by fecal microbiota transplantation. Understanding the interplay between microbiota and disease in terms of microbiota density, host carrying capacity, and microbiota fitness provide new insights into microbiome structure and microbiome targeted therapeutics.Editorial note: This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (<xref ref-type="decision-letter" rid="SA1">see decision letter</xref>).
Effects of delay on episodic memory retrieval by children with autism spectrum disorder
Authors: Almeida Telma Sousa , Lamb Michael E. , Weisblatt Emma J. 
Published: January 2019

AbstractTwenty‐seven 6‐ to 15‐year‐old children with autism spectrum disorder (ASD) and 32 typically developing (TD) children were questioned about their participation in a set of activities after a 2‐week delay and again after a 2‐month delay using a best practice interview protocol. Interviews were coded for completeness with respect to the gist of the event, the number of narrative details provided, and accuracy. Results indicated that children with ASD did not differ from TD peers on any dimensions of memory after both delays. Specifically, both groups of children provided equivalently complete accounts on both occasions. However, children in both groups provided significantly fewer narrative details about the event in the second interview, and the accuracy rates were lower. The findings indicate that, like TD children, children with ASD can provide meaningful and reliable testimony about an event they personally experienced, but several aspects of their memory reports deteriorate over time.
Semipermanent Copper Nanowire Network with an Oxidation‐Proof Encapsulation Layer
Authors: Hong Insic , Roh Yeonwook , Koh Je‐Sung , Na Seonyeob , Kim Taewi , Lee Eunhan , An Hyeongi , Kwon Jinhyeong , Yeo Junyeob , Hong Sukjoon , Lee Kyu‐Tae , Kang Daeshik , Ko Seung Hwan , Han Seungyong 
Published: January 2019

AbstractCopper nanowires (Cu NWs) have gained attention as an alternative to noble metal nanowires due to their affordable price, but their susceptibility to rapid oxidization in ambient conditions has remained a critical limitation for their practical usage. Many studies have been conducted to address this disadvantage but have been successful only in terms of oxidation prevention at certain temperatures, leaving the matter of oxidation at high temperatures unresolved. In this article, a simple encapsulation structure made of a polyimide and SiOx thin film is presented that effectively prevents the penetration of oxygen and moisture into the Cu NW network. This structure, furthermore, boasts excellent stability at high temperature (≈350 °C) and in underwater, acidic chemical, and abrasive conditions.
New High‐Power LEDs Open Photochemistry for Near‐Infrared‐Sensitized Radical and Cationic Photopolymerization
Authors: Schmitz Christian , Pang Yulian , Gülz André , Gläser Marina , Horst Joachim , Jäger Martin , Strehmel Bernd 
Published: January 2019

AbstractCyanines derived from heptamethines were investigated in combination with iodonium salts as initiators of the radical polymerization of tripropylene glycol diacrylate and epoxides derived from bisphenol‐A‐diglycidylether. A new near‐infrared (NIR) LED prototype emitting at 805 nm with an exposure intensity of 1.2 W cm−2 facilitated initiation of both radical and cationic polymerization using sensitizers derived from cyanines. This new light‐emitting device has brought new insight into the photochemistry of cyanines with the general structure 1 because a combination of photonic and thermal processes strongly influences reaction pathways. In particular, cationic cyanines comprising a cyclopentene moiety and diphenylamino group in the center initiated the cationic polymerization of epoxides. Selective oxidation of this unit explains why specifically these derivatives may function as initiators for cationic polymerization. In contrast, when the diphenylamino group was replaced by a barbital group at the meso‐position cationic polymerization of epoxides was not initiated.
Electrochemical Carbon Dioxide Splitting
Authors: Xie Jiafang , Huang Yiyin , Wu Maoxiang , Wang Yaobing 
Published: January 2019

AbstractTo realize renewable energy storage with a reduced carbon footprint for replacing fossil fuel and closing the unbalanced carbon cycle, electrochemical CO2 splitting, commonly containing aqueous CO2 reduction and water oxidation as core reactions, has received booming interest for its unique ability to produce chemicals and fuels from CO2 powered by renewable electricity. In this Review, recent progress of electrochemical CO2 splitting from a fundamental understanding to practical control of the main performance index, including production rate, product selectivity, and energetic efficiency, is discussed with the highlight of the methodologies used to increase CO2 supply in water media and active site design. The roles of the main components in electrochemical CO2 splitting devices, such as catalyst, electrode, electrolyzer, membrane, and electrolyte, are discussed. Finally, we also provide personal perspectives to highlight the opportunities to overcome low stability and limited selectivity for practical electrochemical CO2 splitting.
Entwickelnder Transfer fachdidaktischer Outreach‐Projekte
Authors: Emden Markus , Risch Björn 
Published: January 2019

ZusammenfassungDie Popularität moderner Science Center animiert Kollegen aus den Fachdidaktiken, selbst Mitmachausstellungen zu organisieren und so die Faszination am eigenen Fach weiterzugeben. Jedoch sind die Einrichtungskosten und der Unterhaltungsaufwand für dauerhaft installierte Ausstellungen immens und nur selten tragen sich die Angebote selbst. Der Beitrag zeigt, wie ein kostengünstiges und niederschwelliges Mitmachangebot aus der Pfalz in die schwäbische Ostalb übersetzt werden konnte, wobei die Eigenheiten beider Durchführungen dargestellt werden. Darüber hinaus wird ein weiterer Ansatz zur einfachen Erfahrbarmachung naturwissenschaftlicher Phänomene vorgestellt. Anliegen dabei ist es, zum Nachmachen zu animieren und Ängste vor dem‚ (zu) großen Projekt‘ Science Center zu nehmen.
Molecular and electronic structure elucidation of Fe2+/Fe3+ complexed chelators used in iron sulphide scale removal in oil and gas wells
Authors: Onawole Abdulmujeeb T. , Hussein Ibnelwaleed A. , Sultan Abdullah , Abdel‐Azeim Safwat , Mahmoud Mohamed , Saad Mohammed A. 
Published: January 2019

ABSTRACTQuantum chemical calculations based on DFT are employed to study the electronic structure and binding affinity of chelators used in the removal of iron sulphide scales. Three chelating agents, EDTA, HEDTA, and DTPA, are considered in this work. The complexes showed a coordination number of 5, 6, and 7 for Fe2+ and Fe3+ ions with HEDTA, EDTA, and DTPA, respectively. However, regarding EDTA, Fe3+ could coordinate with an additional water molecule and form a seven‐coordinate complex. The calculated binding energies agreed with the experimental stability constants of the chelators in the order DTPA > EDTA > HEDTA for both Fe2+/Fe3+ complexes. The binding free energies showed a spontaneous reaction with Fe3+ having a stronger binding affinity than Fe2+ due to electrostatic forces. This investigation provides insights regarding how chelators that are applied in iron sulphide scale removal may be designed by increasing the number of nitrogen atoms to above the number of carboxylate groups.
cryoEM‐Guided Development of Antibiotics for Drug‐Resistant Bacteria
Authors: Belousoff Matthew J. , Venugopal Hari , Wright Alexander , Seoner Samuel , Stuart Isabella , Stubenrauch Chris , Bamert Rebecca S. , Lupton David W. , Lithgow Trevor 
Published: January 2019

AbstractWhile the ribosome is a common target for antibiotics, challenges with crystallography can impede the development of new bioactives using structure‐based drug design approaches. In this study we exploit common structural features present in linezolid‐resistant forms of both methicillin‐resistant Staphylococcus aureus (MRSA) and vancomycin‐resistant Enterococcus (VRE) to redesign the antibiotic. Enabled by rapid and facile cryoEM structures, this process has identified (S)‐2,2‐dichloro‐N‐((3‐(3‐fluoro‐4‐morpholinophenyl)‐2‐oxooxazolidin‐5‐yl)methyl)acetamide (LZD‐5) and (S)‐2‐chloro‐N‐((3‐(3‐fluoro‐4‐morpholinophenyl)‐2‐oxooxazolidin‐5‐yl)methyl) acetamide (LZD‐6), which inhibit the ribosomal function and growth of linezolid‐resistant MRSA and VRE. The strategy discussed highlights the potential for cryoEM to facilitate the development of novel bioactive materials.
Core Structure Engineering in Hole‐Transport Materials to Achieve Highly Efficient Perovskite Solar Cells
Authors: Ji Yu , He Bizu , Lu Huiqiang , Xu Jing , Wang Rui , Jin Yanzi , Zhong Cheng , Shan Yahan , Wu Fei , Zhu Linna 
Published: January 2019

AbstractIn this work, the thiadiazolopyridine (PT) unit was introduced as the core structure, with N3,N3,N6,N6‐tetrakis(4‐methoxyphenyl)‐9‐phenyl‐9 H‐carbazole‐3,6‐diamine as the peripheral group, to obtain a new compound, JY8, for use as a hole‐transport material (HTM) in planar perovskite solar cells (PSCs). Compared with the previously reported JY5 with benzothiadiazole as the core structure, the PT unit with stronger electron‐withdrawing ability enhanced the intermolecular dipole–dipole interaction. Moreover, the introduction of the PT unit made the central part in JY8 more planar than its analogue JY5, which is conducive to charge transport. Field‐emission (FE)‐SEM images suggested a smooth and condense morphology of the JY8 film, which could improve the contact between the perovskite layer and the metal electrode. Space‐charge limitation of current results, steady‐state, and time‐resolved photoluminescence decay curves indicated that JY8 as HTM facilitated hole extraction and hole transport. Consequently, planar PSCs fabricated with JY8 as the HTM exhibited a decent efficiency of 19.14 % with a high fill factor of 81 %.
Secret key rate proof of multicarrier continuous‐variable quantum key distribution
Authors: Gyongyosi Laszlo , Imre Sandor 
Published: January 2019

SummaryWe prove the secret key rate formulas and derive security threshold parameters of multicarrier continuous‐variable quantum key distribution CVQKD. In a multicarrier CVQKD scenario, the Gaussian input quantum states of the legal parties are granulated into Gaussian subcarrier continuous variables (CVs). The multicarrier communication formulates Gaussian subchannels from the physical quantum channel, each dedicated to the transmission of a subcarrier CV. The Gaussian subcarriers are decoded by a unitary CV operation, which results in the recovered single‐carrier Gaussian CVs. We derive the formulas through the adaptive multicarrier quadrature division (AMQD) scheme, the singular value decomposition (SVD)–assisted AMQD, and the multiuser AMQD multiuser quadrature allocation (MQA). We prove that the multicarrier CVQKD leads to improved secret key rates and higher tolerable excess noise in comparison with single‐carrier CVQKD. We derive the private classical capacity of a Gaussian subchannel and the security parameters of an optimal Gaussian collective attack in the multicarrier setting. We reveal the secret key rate formulas for one‐way and two‐way multicarrier CVQKD protocols, assuming homodyne and heterodyne measurements and direct and reverse reconciliation. The results reveal the physical boundaries of physically allowed Gaussian attacks in a multicarrier CVQKD scenario and confirm that the improved transmission rates lead to enhanced secret key rates and security thresholds.
Sodium reduction strategies through use of meat extenders (white button mushrooms vs. textured soy) in beef patties
Authors: Wong Kristin M. , Corradini Maria G. , Autio Wesley , Kinchla Amanda J. 
Published: January 2019

AbstractLowering the sodium content in meat products, particularly in beef patties, can be challenging because sodium plays many functional roles in these products. Meat extenders can contribute to lower sodium content by imparting complementary flavors while reducing caloric and sodium content. A systematic comparison of two meat extenders, namely mushrooms and textured soy (TSP) in terms of physical and sensory characteristics, is presented herein. The physical properties of the samples suggested that the use of mushroom and TSP extender would perform statistically similar to an all‐meat control depending on the level of substitution. Hedonic sensory analysis showed meat extension using mushrooms yielded liking scores more similar to the all‐meat formulations than TSP in reduced sodium applications. The results of this research suggest that mushrooms have the potential to be successfully incorporated into reduced sodium meat products to provide a healthier product.
User fee exemption and maternal health care utilisation at mission health facilities in Malawi: An application of disequilibrium theory of demand and supply
Authors: Manthalu Gerald 
Published: January 2019

AbstractThe literature on health care utilisation has focussed on the interaction of supply and demand factors in determining utilisation. At the aggregate level, studies have modelled the simultaneity of demand and supply, and different methods have been used. This study proposes an alternative framework for modelling utilisation, which yet separates demand and supply factors, the disequilibrium theory of demand and supply. This theory is useful in modelling data that reflect that not all health care demand is met by health care providers and not all health care supply is taken by consumers. Such disequilibrium arises due to rigid prices and quantity rationing. We use the theory to model maternal health care utilisation and user fee exemption at mission health care facilities in Malawi. The study uses switching regression methods and data from the Malawi Health Management Information System. Results show that user fee exemption is associated with increased utilisation of maternal health care. Demand and supply regime classification shows that many of the health facilities met much of the demand, whereas the rest only provided as much maternal care as their maximum capacity. In the latter case, intended maternal health care utilisation targets may not have been met.
Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA
Authors: Uchida Satoshi , Kataoka Kazunori 
Published: January 2019

AbstractNonviral delivery of plasmid (p)DNA or messenger (m)RNA is a safe and promising therapeutic option to continuously supply therapeutic proteins into diseased tissues. In most cases of in vivo pDNA and mRNA delivery, these nucleic acids are loaded into carriers based on cationic polymers and/or lipids to prevent nuclease‐mediated degradation before reaching target cells. The carriers should also evade host clearance mechanisms, including uptake by scavenger cells and filtration in the spleen. Installation of ligands onto the carriers can facilitate their rapid uptake into target cells. Meanwhile, carrier toxicity should be minimized not only for preventing undesirable adverse responses in patients, but also for preserving the function of transfected cells to exert therapeutic effects. Long‐term progressive improvement of platform technologies has helped overcome most of these issues, though some still remain hindering the widespread clinical application of nonviral pDNA and mRNA delivery. This review discusses design concepts of nonviral carriers for in vivo delivery and the issues to be overcome, focusing especially on our own efforts using polyplex micelles. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 107A: 978–990, 2019.