bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phosphorous Immobility During Formation of the Layered Sulfate Deposits of the Burns Formation at Meridiani Planum
Authors: McCollom Thomas M. , Donaldson Chris , Moskowitz Bruce , Berquó Thelma S. , Hynek Brian 
Published: May 2018

AbstractThe relatively high abundance of phosphorous (P) in rocks from the Martian crust makes it a potentially useful element for tracking geochemical processes. Owing to the high solubility of common P‐bearing minerals such as apatite at low pH, P is widely thought to be mobile under acid‐sulfate conditions. Accordingly, transport of P by acidic fluids has been invoked to explain enrichments or depletions of this element in some rocks and soils from Mars. The sediments that compose the layered‐sulfate deposits of the Burns formation at Meridiani Planum were originally derived from a basaltic precursor but appear to have been exposed to acidic, sulfate‐rich fluids at several intervals during their history. Yet, assessment of the chemical composition of the bedrocks indicates that they maintain pristine igneous P:Ti ratios and P abundances similar to Martian basalts, indicating that there has been little or no transport of P into or out of the deposits at any stage in their formation. Potential reservoirs for P in the deposits include basaltic glass, secondary Fe‐ or Al‐phosphate minerals, substitution of PO4 for SO4 in alunite‐jarosite group minerals, or surface adsorption. Although Fe‐phosphates were not among the minerals detected by the Mössbauer spectrometer onboard the Opportunity rover at Meridiani, it might be difficult to detect such minerals even if they are present because they are below the detection limit or have signatures similar to other minerals. Overall, the results demonstrate that P can be immobile even in some acid‐sulfate environments on Mars and Earth.
Kinematic Features of Jaw and Lips Distinguish Symptomatic From Presymptomatic Stages of Bulbar Decline in Amyotrophic Lateral Sclerosis
Authors: Bandini Andrea , Green Jordan R. , Wang Jun , Campbell Thomas F. , Zinman Lorne , Yunusova Yana 
Published: May 2018

PurposeThe goals of this study were to (a) classify speech movements of patients with amyotrophic lateral sclerosis (ALS) in presymptomatic and symptomatic phases of bulbar function decline relying solely on kinematic features of lips and jaw and (b) identify the most important measures that detect the transition between early and late bulbar changes.MethodOne hundred ninety-two recordings obtained from 64 patients with ALS were considered for the analysis. Feature selection and classification algorithms were used to analyze lip and jaw movements recorded with Optotrak Certus (Northern Digital Inc.) during a sentence task. A feature set, which included 35 measures of movement range, velocity, acceleration, jerk, and area measures of lips and jaw, was used to classify sessions according to the speaking rate into presymptomatic (> 160 words per minute) and symptomatic (< 160 words per minute) groups.ResultsPresymptomatic and symptomatic phases of bulbar decline were distinguished with high accuracy (87%), relying only on lip and jaw movements. The best features that allowed detecting the differences between early and later bulbar stages included cumulative path of lower lip and jaw, peak values of velocity, acceleration, and jerk of lower lip and jaw.ConclusionThe results established a relationship between facial kinematics and bulbar function decline in ALS. Considering that facial movements can be recorded by means of novel inexpensive and easy-to-use, video-based methods, this work supports the development of an automatic system for facial movement analysis to help clinicians in tracking the disease progression in ALS.
Exploring the realm of scaled solar system analogues with HARPS
Authors: Barbato D. , Sozzetti A. , Desidera S. , Damasso M. , Bonomo A. S. , Giacobbe P. , Colombo L. S. , Lazzoni C. , Claudi R. , Gratton R. , LoCurto G. , Marzari F. , Mordasini C. 
Published: May 2018

Context. The assessment of the frequency of planetary systems reproducing the solar system’s architecture is still an open problem in exoplanetary science. Detailed study of multiplicity and architecture is generally hampered by limitations in quality, temporal extension and observing strategy, causing difficulties in detecting low-mass inner planets in the presence of outer giant planets.
Aims. We present the results of high-cadence and high-precision HARPS observations on 20 solar-type stars known to host a single long-period giant planet in order to search for additional inner companions and estimate the occurence rate fp of scaled solar system analogues – in other words, systems featuring lower-mass inner planets in the presence of long-period giant planets.
Methods. We carried out combined fits of our HARPS data with literature radial velocities using differential evolution MCMC to refine the literature orbital solutions and search for additional inner planets. We then derived the survey detection limits to provide preliminary estimates of fp.
Results. We generally find better constrained orbital parameters for the known planets than those found in the literature; significant updates can be especially appreciated on half of the selected planetary systems. While no additional inner planet is detected, we find evidence for previously unreported long-period massive companions in systems HD 50499 and HD 73267. We finally estimate the frequency of inner low mass (10–30 M⊕) planets in the presence of outer giant planets as fp < 9.84% for P < 150 days.
Conclusions. Our preliminary estimate of fp is significantly lower than the literature values for similarly defined mass and period ranges; the lack of inner candidate planets found in our sample can also be seen as evidence corroborating the inwards-migration formation model for super-Earths and mini-Neptunes. Our results also underline the need for high-cadence and high-precision followup observations as the key to precisely determine the occurence of solar system analogues.
Three-dimensional maps of interstellar dust in the Local Arm: using Gaia, 2MASS, and APOGEE-DR14
Authors: Lallement R. , Capitanio L. , Ruiz-Dern L. , Danielski C. , Babusiaux C. , Vergely L. , Elyajouri M. , Arenou F. , Leclerc N. 
Published: May 2018

Context. Gaia data and stellar surveys open the way to the construction of detailed 3D maps of the Galactic interstellar (IS) dust based on the synthesis of star distances and extinctions. Dust maps are tools of broad use, also for Gaia-related Milky Way studies.
Aims. Reliable extinction measurements require very accurate photometric calibrations. We show the first step of an iterative process linking 3D dust maps and photometric calibrations, and improving them simultaneously.
Methods. Our previous 3D map of nearby IS dust was used to select low-reddening SDSS/APOGEE-DR14 red giants, and this database served for an empirical effective temperature- and metallicity-dependent photometric calibration in the Gaia G and 2MASS Ks bands. This calibration has been combined with Gaia G-band empirical extinction coefficients recently published, G, J, and Ks photometry and APOGEE atmospheric parameters to derive the extinction of a large fraction of the survey targets. Distances were estimated independently using isochrones and the magnitude-independent extinction KJ−Ks. This new dataset has been merged with the one used for the earlier version of dust map. A new Bayesian inversion of distance-extinction pairs has been performed to produce an updated 3D map.
Results. We present several properties of the new map. A comparison with 2D dust emission reveals that all large dust shells seen in emission at middle and high latitudes are closer than 300 pc. The updated distribution constrains the well-debated, X-ray bright North Polar Spur to originate beyond 800 pc. We use the Orion region to illustrate additional details and distant clouds. On the large scale the map reveals a complex structure of the Local Arm. Chains of clouds of 2–3 kpc in length appear in planes tilted by ≃15° with respect to the Galactic plane. A series of cavities oriented along a l ≃ 60–240° axis crosses the Arm.
Conclusions. The results illustrate the ongoing synergy between 3D mapping of IS dust and stellar calibrations in the context of Gaia. Dust maps provide prior foregrounds for future calibrations appropriate to different target characteristics or ranges of extinction, allowing us in turn to increase extinction data and produce more detailed and extended maps.
Endoscopic submucosal dissection (ESD) for anal high-grade intraepithelial neoplasia: a case report
Authors: Neureiter Daniel , Holzinger Josef , Kiesslich Tobias , Klieser Eckhard , Berr Frieder , Wagner Andrej 
Published: May 2018

AbstractAnal intraepithelial neoplasia (AIN) is a precursor of anal carcinoma. Conventional therapy is based on topical and local ablative approaches. However, the recurrence rates are very high, leading to repetitive treatment sessions and need for long-term surveillance. Endoscopic submucosal dissection (ESD) is an established treatment for malignant early neoplasias of the gastrointestinal tract, especially in the esophagus, stomach, and colorectum. Japanese centers have reported few cases of ESD for early anal carcinoma. We report a case of high-grade AIN diagnosed with magnifying narrow-band imaging and chromoendoscopy that was resected R0 with ESD en bloc.
Ombuoside from Gynostemma pentaphyllum Protects PC12 Cells from L-DOPA-Induced Neurotoxicity
Authors: Davaasambuu Uchralsaikhan , Park Hyun , Park Keun , Lee Chong , Hwang Bang , Lee Myung 
Published: May 2018

AbstractThis study investigated the effects of ombuoside on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced neurotoxicity in PC12 cells. Ombuoside did not affect cell viability at concentrations of up to 50 µM for 24 h, and ombuoside (1, 5, and 10 µM) significantly inhibited L-DOPA-induced (100 and 200 µM) decreases in cell viability. L-DOPA (100 and 200 µM) induced sustained phosphorylation of extracellular signal-regulated kinases (ERK1/2) for 6 h, which were significantly decreased by cotreatments with ombuoside (1, 5, and 10 µM). L-DOPA (100 and 200 µM) alone significantly increased c-Jun N-terminal kinase (JNK1/2) phosphorylation for 6 h and cleaved-caspase-3 expression for 24 h, both of which were partially, but significantly, blocked by ombuoside (1, 5, and 10 µM). In addition, ombuoside (1, 5, and 10 µM) significantly restored the L-DOPA-induced (100 and 200 µM) decrease in superoxide dismutase (SOD) activity for 24 h. Taken together, these findings indicate that ombuoside protects against L-DOPA-induced neurotoxicity by inhibiting L-DOPA-induced increases in sustained ERK1/2 and JNK1/2 phosphorylation and caspase-3 expression and L-DOPA-induced decrease in SOD activity in PC12 cells. Thus, ombuoside might represent a novel neuroprotective agent that warrants further study.
Have English translations of Wagner’s Ring of the Nibelung, an icon of German culture, been affected by the changing relationship between Germany and Britain in the twentieth century?
Authors: Wilson-deRoze Karen 
Published: May 2018

Abstract
To some, the message of The Ring of the Nibelung is that love and sacrifice can redeem the world; for others, like G.B. Shaw1, it is a capitalist drama. For many, the Ring is quintessentially German, for others, its mythic themes are universal. Its Germanness is examined in this article in terms of nationalism expressed as a dialectic between German and non-German, specifically Jews. I address the debate of whether or not Wagner’s anti-Semitism is evident in the libretto and music of the Ring and discuss whether translators, working before and after the two World Wars, have censored or adjusted Wagner’s language for present-day tastes. I conclude that any interpretation of the Ring as anti-Semitic does not appear to have influenced the translation choices of post-war translators.
Reproduction and reception of the concepts of Confucianism, Buddhism and polygamy
Authors: Choi Jinsil 
Published: May 2018

Abstract
This article investigates how the pre-modern Korean cultural concepts “Confucianism”, “Buddhism” and “polygamy” as represented in Kuunmong, a Korean novel supposedly published in 1689, were reproduced by two English translators with different religious backgrounds and writing in different periods, Reverend James Scarth Gale (1922) and Bishop Richard Rutt (1974); it is also my aim to examine how the concepts were introduced, explained, and received in the target culture. While Gale’s translation reveals a favorable attitude toward Buddhism and polygamy prevailing in the text, Rutt tended to reinterpret and reconstruct those practices in a more critical way. I suggest that this difference may be related to the different social milieu at the times of translating, readers’ expectations, translators’ individual opinions, as well as factors relating to the publishers, reflective of the different agential network in translation.
Adorno refracted
Authors: Baumgarten Stefan 
Published: May 2018

Abstract
Theodor Wiesengrund Adorno’s oeuvre has been widely translated into English, and despite an uneven reception history in the Anglophone world, he can be regarded as a “fashionable”, perhaps even a “celebrity” philosopher in English translation. Whilst it remains an open question to what extent a high intellectual pedigree can be distilled into cultural capital when refracted through the lens of translation, it appears reasonable to assume that key works of German critical theory in English are refracted through a positivist order of discourse, which is at odds with the ideological, or more precisely utopian, convictions of mainstream critical theorists. This article discusses the translational recontextualisation of Adorno’s concept of the “non-identical” and some of its associated conceptual frames.
Three open questions in Diachronic Construction Grammar
Authors: Hilpert Martin 
Published: May 2018

Abstract
A growing number of studies on language change adopt Construction Grammar as a theoretical framework so that there is now a developing field of Diachronic Construction Grammar. As is typical of any emerging linguistic theory, many aspects of Diachronic Construction Grammar are still not clarified explicitly, or they are understood in different ways by different researchers. There is thus a need for some meta-theoretical reflection. This paper identifies three questions in Diachronic Construction Grammar that are currently unresolved. These three questions pertain to the status of constructions as mental representations of language, the emergence of new constructions, and the way in which nodes and connections are viewed as parts of the constructional network. By airing these questions, this paper hopes to stimulate further discussion.
Pseudocoordination in Norwegian
Authors: Kinn Torodd 
Published: May 2018

Abstract
Pseudocoordination in the Scandinavian languages is often claimed to involve grammaticalization. Such coordination is exemplified by Norwegian sitte og lese ‘be reading’ (literally: ‘sit and read’), gå og se ‘go and see’, and løpe rundt og leke ‘run around and play’, where the first verb in some cases expresses partly or even mainly grammatical meaning. Using a large contemporary corpus, the article explores constructional variants involving atelic motion, like løpe rundt ‘run around’. Indicators of grammaticalization such as paradigmatization, bleaching, and decategorialization of the first verb are in focus, as well as the concomitants of grammaticalization in the larger construction. Some first verbs do show signs of grammaticalization, but this is not a general characteristic of the construction.
Reduction or expansion? A bit of both
Authors: Neels Jakob , Hartmann Stefan 
Published: May 2018

Abstract
This paper presents a diachronic analysis of the German quantifier/degree-modifier constructions ein bisschen (‘a bitDIM’) and ein wenig (‘a little’). On the basis of data from two historical corpora, we examine to what extent these constructions followed a grammaticalization path comparable to the one Traugott (e.g. 2008a) observed for their English counterparts. Quantitative analyses on their gradual context expansion are combined with qualitative analyses on potential bridging contexts for reanalysis. Their combined histories suggest that the older German modifiers may have served as attractor sets for an increasingly strengthened mid-level quantifier/degree-modifier schema, promoting the emergence of younger modifiers. These observations stress the crucial role that network links between constructions can play in grammaticalization.
Type frequency, productivity and schematicity in the evolution of the Latin secundum NP construction
Authors: Guardamagna Caterina 
Published: May 2018

Abstract
This paper adopts a constructional approach as a heuristic to explore the changes undergone by Latin secundum NP ‘according to NP’, considering both its frequency and its network organisation. My data demonstrate a significant syntactic and host-class expansion of secundum NP between the years BC 106 – AD 17 and a support to Barðdal’s (2008) model of productivity. The vocabulary growth curve for the construction also suggests that the productivity of secundum NP remains high in all the periods considered. Finally, the discussion highlights the role played by the social context in stimulating some of the changes observed, which is crucial in order to interpret the quantitative data.
Suppressive effects of the peel of Citrus kawachiensis (Kawachi Bankan) on astroglial activation, tau phosphorylation, and inhibition of neurogenesis in the hippocampus of type 2 diabetic db/db mice
Authors: Okuyama Satoshi , Shinoka Wakana , Nakamura Kumi , Kotani Maho , Sawamoto Atsushi , Sugawara Kuniaki , Sudo Masahiko , Nakajima Mitsunari , Furukawa Yoshiko 
Published: May 2018

ABSTRACT
We previously reported that the dried peel powder of Citrus kawachiensis exerted anti-inflammatory effects in the brain in several animal models. Hyperglycemia induces inflammation and oxidative stress and causes massive damage in the brain; therefore, we herein examined the anti-inflammatory and other effects of the dried peel powder of C. kawachiensis in the streptozotocin-induced hyperglycemia mice model and in the type 2 diabetic db/db mice model. The C. kawachiensis administration inhibited microglial activation in the hippocampus in the streptozotocin-injected mice. Moreover, The C. kawachiensis treatment inhibited astroglial activation in the hippocampus and the hyperphosphorylation of tau at 231 of threonine and 396 of serine in hippocampal neurons, and also relieved the suppression of neurogenesis in the dentate gyrus of the hippocampus in the db/db mice. It was suggested that the dried peel powder of C. kawachiensis exerts anti-inflammatory and neuroprotective effects in the brain.
Breakthrough Fungal Infections in Patients With Leukemia Receiving Isavuconazole
Authors: Rausch Caitlin R , DiPippo Adam J , Bose Prithviraj , Kontoyiannis Dimitrios P 
Published: May 2018

Abstract
We retrospectively assessed breakthrough invasive fungal infections (b-IFIs) in 100 consecutive patients with leukemia receiving single-agent isavuconazole; 13 had documented b-IFIs (candidiasis in 6, mucormycosis in 4). All b-IFIs were observed in patients with prolonged neutropenia and active leukemia.
Chipping to Destroy Egg Masses of the Spotted Lanternfly, Lycorma delicatula (Hemiptera: Fulgoridae)
Authors: Cooperband Miriam F , Mack Ron , Spichiger Sven-Erik 
Published: May 2018

Abstract
A chipping study was conducted during the winter of 2015 in Berks County, Pennsylvania, to determine efficacy against field collected egg masses of the spotted lanternfly, Lycorma delicatula (White) (Hemiptera: Fulgoridae). Infested Ailanthus altissima Swingle (Sapindales: Simaroubaceae) trees in eastern Pennsylvania were felled and egg masses were counted. Sections were either chipped or allowed to remain intact as controls. Chipped material and intact wood controls were placed in screened barrels and monitored for emergence. No L. delicatula nymphs were found in the chipped treatment, as opposed to hundreds of nymphs per barrel in the intact control treatment. We conclude that mid-winter chipping, using the standard 1-inch in 2-dimension chip size, is a quarantine safe mitigation method suitable for treating wood infested with L. delicatula egg masses.
MiRNA-181d Expression Significantly Affects Treatment Responses to Carmustine Wafer Implantation
Authors: Sippl Christoph , Ketter Ralf , Bohr Lisa , Kim Yoo Jin , List Markus , Oertel Joachim , Urbschat Steffi 
Published: May 2018

Abstract

BACKGROUND
Standard therapeutic protocols for glioblastoma, the most aggressive type of brain cancer, include surgery followed by chemoradiotherapy. Additionally, carmustine-eluting wafers can be implanted locally into the resection cavity.

OBJECTIVE
To evaluate microRNA (miRNA)-181d as a prognostic marker of responses to carmustine wafer implantation.

METHODS
A total of 80 glioblastoma patients (40/group) were included in a matched pair analysis. One group (carmustine wafer group) received concomitant chemoradiotherapy with carmustine wafer implantation (Stupp protocol). The second group (control group) received only concomitant chemoradiotherapy. All tumor specimens were subjected to evaluations of miRNA-181d expression, results were correlated with further individual clinical data. The Cancer Genome Atlas (TCGA) dataset of 149 patients was used as an independent cohort to validate the results.

RESULTS
Patients in the carmustine wafer group with low miRNA-181d expression had significantly longer overall (hazard ratio [HR], 35.03, [95% confidence interval (CI): 3.50-350.23], P = .002) and progression-free survival (HR, 20.23, [95% CI: 2.19-186.86], P = .008) than patients of the same group with a high miRNA-181d expression. These correlations were not observed in the control group. The nonsignificance in the control group was confirmed in the independent TCGA dataset. The carmustine wafer group patients with low miRNA-181d expression also had a significantly longer progression-free (P = .049) and overall survival (OS) (P = .034), compared with control group patients. Gross total resection correlated significantly with longer OS (P = .023).

CONCLUSION
MiRNA-181d expression significantly affects treatment responses to carmustine wafer implantation.