bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single versus Split Dose of Iron Optimizes Hemoglobin Mass Gains at 2106 m Altitude
Authors: HALL REBECCA , PEELING PETER , NEMETH ELIZABETA , BERGLAND DAN , MCCLUSKEY WALTER T. P. , STELLINGWERFF TRENT 
Published: November 2018

ABSTRACT

Purpose
To determine if a single versus a split equivalent daily dose of elemental iron was superior for hemoglobin mass (Hbmass) gains at altitude while minimizing gastrointestinal (GI) discomfort.

Methods
Twenty-four elite runners attended a 3.1 ± 0.3 wk training camp (Flagstaff, AZ; 2106 m). A two-group design, randomized and stratified to baseline Hbmass, sex, and ferritin (>30 μ·L−1), was implemented daily as: 1) single dose of 1 × 200 mg (pm only, SINGLE) versus 2) split dose of 2 × 100 mg (am and pm; SPLIT) elemental iron (ferrous fumarate). The Hbmass and venipuncture assessments were completed upon arrival and departure (±2 d) from camp for ferritin, hepcidin, and erythroferrone (ERFE) concentrations. Validated food frequency, GI distress, menstrual blood loss (MBL) and training questionnaires were implemented throughout. Univariate analysis was used to compare Hbmass, with baseline ferritin, dietary iron intake, MBL, and training volume used as covariates.

Results
Both conditions increased Hbmass from baseline (P < 0.05), with SINGLE (867.3 ± 47.9 g) significantly higher than SPLIT (828.9 ± 48.9 g) (P = 0.048). The GI scores were worse in SINGLE for weeks 1 and 2 combined (SINGLE, 18.0 ± 6.7 points; SPLIT, 11.3 ± 6.9 points; P = 0.025); however, GI scores improved by week 3, resulting in no between-group differences (P = 0.335). Hepcidin significantly decreased over time (P = 0.043) in SINGLE, with a nonsignificant decrease evident in SPLIT (~22%). ERFE significantly decreased in both groups (~28.5%; P < 0.05). No between-group differences existed for ERFE, hepcidin, food frequency, MBL, or daily training outcomes (P > 0.05).

Conclusions
A single nightly 200-mg dose of elemental iron was superior to a split dose for optimizing Hbmass changes at altitude in runners over an approximately 3-wk training camp.
Monitoring biologics in inflammatory bowel disease (IBD) using the Patients Know Best electronic portal: pilot study of uptake, acceptability and outcomes
Authors: Kamperidis Nikolaos , O'Connor Marian , Arebi Naila 
Published: November 2018

Background: The number of inflammatory bowel disease (IBD) patients on biologics in the UK is increasing; this and the expansion of available drugs have contributed to delays in delivering treatment. E-health applications, such as the Patients Know Best (PKB) personal online healthcare record system, can improve efficiency of patient management in stable IBD. This pilot study aimed to explore the uptake, acceptability and outcomes of PKB in the management of patients starting biologics. Methods: IBD patients prescribed biologics were invited to register and trained online. The authors measured the number of new starters, PKB registrants, time intervals to treatment and the nature of online activity. Patients using the application received an evaluation questionnaire 6 months after enrolment. Results: Out of 40 patients newly started on biologics, 33 years were included, with a mean (SD) age of 44.3 (13.3) years. The mean time interval from decision to treatment administration was 82.7 days (44.0). Ten patients raised at least one issue on PKB; 45 new issues were raised, mostly relevant to active disease (18/45), adverse events of treatments (6/45) and the funding application process (5/45)—39 were resolved online. Of patients, 16 answered the questionnaire, and 11 found it at least somewhat helpful. More training was requested. Conclusions: The use of PKB did not accelerate the process of drug administration. However, patients engaged with the use of the platform, several issues were raised and most of these were resolved electronically. Regular training and individual treatment plans for patients starting biologics may optimise PKB's use for long-term monitoring.
Girlhood, bride-kidnapping and the postsocialist moment in Mángshān (Blind Mountain) (Li, 2007) and Boz Salkyn (Pure Coolness) (Abdyjaparov, 2007)
Authors: Taylor-Jones Kate 
Published: November 2018

Abstract
China and Kyrgyzstan are at the point of national development where the interplay between a national past and a globalized future is still hotly debated. Both nations are at the crux of the global questions related to the universal dilemmas posed by the collapse of the revolutionary socialist challenge to the hegemony of capitalism. This article will examine the interplay between gender and the vision of postsocialist modernity that is found in two films. Blind Mountain (Li, 2007) and Pure Coolness (Abdyjaparov, 2007) both present the respective stories of teenagers forced into marriage as part of a ‘tradition’ that is supported by the broader local community (as opposed to being the act of an individual male kidnapper). I will explore how the girl simultaneously represents a vision of a localized space while operating as an indicative sign of cultural difference. In short, she is the site of the transmission of ideals of gender and modernity between moments in national development. We, therefore, see the girl caught in the crosshair of modernity, sexuality, tradition, nostalgia and capitalism in communities that, as will be explored, are struggling to find a sense of self in the Asian postsocialist moment.
Morphological characteristics and power output in professional road cyclists during the competition phase
Authors: Lewandowski Andrzej , Kowalewski Marcin , Kowalik Tomasz , Piekorz Zuzanna 
Published: November 2018

Abstract
Study aim: The purpose of this study was to investigate changes in the power output and major morphological characteristics during the competition phase. We hypothesised that substantial overloads occurring during this stage cause a decrease in body mass, fat and power output levels in the cyclists.
Material and methods: Nine members from an affiliated Professional Cycling Group ActiveJet Team were observed during the period between January and September. Their mean age was calculated as 25.1 ± 1.6 years. Each month the main somatic fea­tures were determined and the BMI and Rohrer index were measured. The level of adipose tissue was checked using the Tanita BC-418 Ma and the Schoeberer Rad Messtechnik SRM training system was employed to record the maximum level of power output. The following tests were used to collect data: Shapiro-Wilk and ANOVA (assessment of the distribution of variables), Duncan (assessment of the changes of variables), and Pearson correlation coefficient (assessment of power dependence and morphological features). A significance coefficient of α = 0.05 was assumed.
Results: The research of the studied group revealed a steady decrease in the body mass and fat percentage but no significant differences in power output levels. Its peak was reached in the middle of the starting phase (1195.3 ± 222.3 W) and the lowest level was noted during the last month of our observation (1114.1 ± 152.1 W; D = 81.2 W, p = 0.088). Correlations were found between body mass, fat composition and power output levels: moderate for mass (r = 0.383-0.778) and fat (r = 0.352-0.629) content to power output and small negative for height to power output. In most cases, however, they were either weak or low (r = -0.017-0.339).
Conclusions: Significant changes in the morphological characteristics (body weight 70.2 ± 6.4-69.2 ± 5.9 kg, p < 0.001; BMI 21.4 ± 1.9-21.1 ± 1.7, p < 0.001; Rohrer index 1.18 ± 0.11-1.16 ± 0.10, p < 0.001; fat 9.2 ± 3.2-8.2 ± 2.3, p < 0.001) and no differences in power output combined (1151.0 ± 272.4-1114.1 ± 152.1 W, p = 0.434) with medium correlations of these determinants (body height - 2.53-0.354; body weight 0.383-0.778; fat 0.352-0.629) indicate the significance of motor charac­teristics in road racing cyclists. Thus levels in its competency and performance outcomes are determined to a greater extent by factors other than the somatic characteristics.
Men’s embodied occupational narratives: An empirical study revisited
Authors: Robinson Victoria 
Published: November 2018

Abstract
This article revisits data from a UK ESRC-funded project which previously was used to argue that there are implications of different occupational cultures for the living out of men’s masculine and embodied identities. Examining embodied narratives within occupational cultures commonly stereotyped as ‘masculine’ or ‘feminine’ (here, the professions of hairdressing, estate agency and firefighting), revealed how men conform to, draw upon and resist, even reinvent the gendered stereotypes associated with these occupations. Such a focus enables men’s embodied narratives to be listened to in terms of their diversity, fluidity and mobility. Through the data, it emerges that the outcome of particular forms of embodied practices can act to not only reinforce, but also to destabilize or undo masculinity in its hegemonic or traditional forms. Here, I revisit some of the conclusions drawn from this original study to re-focus on the men’s telling of their embodied narratives within and cross spheres and over the life course. In so doing, I consider how the researchers in the project could, potentially at least, have interpreted those narratives differently at times. In conclusion, I also raise issues to start to think more comparatively and in an interdisciplinary context, about men’s body narratives.
Ritual Artifacts as Symbolic Habits
Authors: Magnani Lorenzo 
Published: November 2018

Abstract
The concepts of manipulative abduction and of extending, disembodying, and distributing the mind can help delineate important aspects of the role of habits, rituals, and symbols in human cognition, including when new concepts are created. Taking advantage of some psychoanalytical and anthropological issues, I will show how symbolic habits in rituals can function as memory mediators which are able to play significant roles in human cognition and action. They can maximize abducibility and so recoverability of knowledge contents, including at the unconscious level.
An efficient sequential learning algorithm in regime-switching environments
Authors: Kim Jaeho , Lee Sunhyung 
Published: November 2018

AbstractWe provide a novel approach of estimating a regime-switching nonlinear and non-Gaussian state-space model based on a particle learning scheme. In particular, we extend the particle learning method in Liu, J., and M. West. 2001. “Combined Parameter and State Estimation in Simulation-Based Filtering.” InSequential Monte Carlo Methods in Practice, 197–223. Springer. by constructing a new proposal distribution for the latent regime index variable that incorporates all available information contained in the current and past observations. The Monte Carlo simulation result implies that our approach categorically outperforms a popular existing algorithm. For empirical illustration, the proposed algorithm is used to analyze the underlying dynamics of US excess stock return.
Safety Factor for the New Exact Plasma Equilibria
Authors: Bogoyavlenskij Oleg 
Published: November 2018

Abstract
An exact formula for the limit of the safety factor q at a magnetic axis is derived for the general up-down asymmetric plasma equilibria possessing axial symmetry, generalizing Bellan’s formula for the up-down symmetric ones. New exact axisymmetric plasma equilibria depending on arbitrary parameters α, ξ, bkn
, zkn
, where k = 1, ⋯, M, n = 1⋯, N, are constructed (α ≠ 0 is a scaling parameter), which are up-down asymmetric in general. The equilibria are not force-free if ξ ≠ 0 and satisfy Beltrami equation if ξ = 0. For some values of ξ the magnetic field and electric current fluxes have isolated invariant toroidal magnetic rings, for another ξ they have invariant spheroids (blobs) and for some values of ξ both invariant toroidal rings and spheroids (blobs). A generalization of the Chandrasekhar – Fermi – Prendergast magnetostatic model of a magnetic star is presented where plasma velocity V(x) is non-zero.
Pengukuran Coverage Outdoor Wireless LAN Dengan Metode Visualisasi Di Universitas Islam Negeri Sunan Gunung Djati Bandung
Authors: Hamidi Eki Ahmad Zaki , Ismail Nanang , Syahyadin Ramadhan 
Published: November 2018

Universitas Islam Negeri Sunan Gunung Djati Bandung merupakan salah satu instansi pendidikan yang memanfaatkan wireless LAN sebagai media pembelajaran dan informasi, namun banyaknya penggunaan frekuensi dan channel pada wireless LAN dapat menyebabkan overlap hingga terjadi interferensi sinyal. Agar mendapatkan coverage jaringan yang baik pada perangkat outdoor wireless LAN, diperlukan suatu perencanaan dalam penempatan posisi antena dan perhitungan Link Budget yang terdiri dari free space loss, effective isotropically radiated power, received signal level dan system operating margin. Selain itu perhitungan dilakukan secara simulasi dengan menggunakan software Radio Mobile untuk melihat hasil coverage area secara visual. Pengukuran jaringan yang dilakukan terdiri dari 1 antena Server dan 3 access point yang ditempatkan pada posisi yang telah ditentukan berdasarkan kondisi eksisting. Hasil rancangan jaringan yang dianalisis menggunakan perhitungan Link Budget secara teori maupun simulasi dengan nilai parameter System Operating Margin (SOM) terbesar pada server sebesar 47,26 dB, sedangkan pada access point#1 46,26 dB, access point#2 45,76 dB dan access point#3 39,5 dB dimana telah memenuhi batas perancangan sinyal yang baik.
#ChoosePsychiatry #the60secondchallenge – a thematic analysis of videos published on Twitter about reasons for choosing psychiatry
Authors: Cunliffe Jonathan , Hargreaves Helen , Melton William , Abed Reem 
Published: November 2018

This article was migrated. The article was marked as recommended. Aims and Method#ChoosePsychiatry is the Royal College of Psychiatrist’s social media campaign aimed at medical students and foundation doctors to encourage recruitment into psychiatry. This study explored the reasons given for choosing psychiatry in videos uploaded by psychiatrists to Twitter alongside the campaign, through the use of thematic analysis. ResultsEach psychiatrist gave different reasons for choosing psychiatry but four main themes were identified: prior experience of psychiatry, career factors, patient factors and knowledge factors. Both undergraduate and postgraduate experiences were influential in choosing psychiatry. In particular, perceived job satisfaction, an opportunity to deliver holistic care and a sense of making a difference were also influential in choosing psychiatry.Clinical ImplicationsFindings here support efforts to improve the undergraduate experience and to increase foundation posts, as well as maintaining some of the current key messages of the campaign. However, whilst engagement with the videos on Twitter was observed, further consideration of the most appropriate social media platform to ensure engagement with the target audience is needed.
Pseudo-mirror nuclei in the mass regions A~ 170 and A~ 200
Authors: SAYGI Bahadir 
Published: November 2018

The concept of
pseudo-mirror nuclei is based on NπNν scheme introduced
as an extension of NpNnscheme. The NπNν scheme
tells us that if two nuclei from different mass region have equal number of
integrated n-p interaction than the experimental observables E(2+), E(4+)/E(2+)
and B(E2; 2+→ 0+) are expected to be almost equal,
therefore equal number of n-p interaction build similar level schemes up to
certain spin quantum numbers. Pseudo-mirror nuclei have been introduced for the
first time in the mass regions A ~ 100 and A ~ 130 for Mo, Zr, Nd and Ce
nuclei. Later, a systematic work carried
out over a broad region of Segre chart showed
that not only the excitation energies but also related B(E2) values of excited
states in Pseudo-mirror nuclei (PMN) are in good agreement. In the present
work, we present new pseudo-mirror nuclei in the mass region A ~ 170 and A ~
200 for the first time.
Presencia de argumentos filosóficos en la jurisprudencia uruguaya
Authors: Guerra Martín 
Published: November 2018

El presente constituye el trabajo externo final para el curso de Filosofía del Derecho y consiste, básicamente, en el análisis de la argumentación e interpretación jurídica esgrimida por la mayoría integrada del Tribunal de Apelaciones en lo Civil de 6º Turno en la sentencia N° 37/1996, así como la empleada en la discordia de uno de sus integrantes naturales.
No será objeto de estudio, pues, ningún otro elemento vinculado a la sentencia que podría ser de interés en el caso concreto, como ser la base fáctica sobre la que se asienta el pronunciamiento o la valoración de la prueba que realizó cada ministro. Estos elementos se darán por supuestos.
BIOLOGICAL EVALUATION OF SAUSSUREA LAPPA ROOT EXTRACT FOR ANALGESIC AND ANTI- INFLAMMATORY ACTIVITY
Authors: Tejaswi Juluri Krishna Dutta , Rajan R. Govinda , Sara P 
Published: November 2018

The present study was designed to evaluate the Phytochemical Screening for Analgesic and Anti- inflammatory activities of Ethonolic extract of Saussurea lappa. The collected plant root material were washed, shade dried, and size reduced into small pieces. Dried materials were coarsely powdered and macerated with petroleum ether for 72 hrs. The plant material was extracted by using ethanol by the cold maceration method. The study concluded that the root extract have potential bioactive substances that may be used to formulate new drugs. The Flavo-Glycosides content in Ethonolic extract of Saussurea lappa root was extracted and results were compared with the standard for Analgesic and Anti- inflammatory activities. The results were compared with the standard using statistical method. However further investigation was required for structural elucidation and pharmacological properties.
Keywords: Saussurea lappa, Ethonolic, Glycosides, Analgesic, Anti-inflammatory.
CIPROFLOXACIN HYDROCHLORIDE LOADED CHITOSAN NANOPARTICLE GEL: ADVANCED APPROACH FOR ENHANCING PERMEATION AND SUSTAINABILITY OF DRUG RELEASE
Authors: Dev Dhruv , Bhardwaj Urvashi , Prasad D N 
Published: November 2018

Transdermal drug delivery is one of the most reliable, appealing and effective technique which provides controlled and constant administration of drug. The aim of the study was to develop a gel form of nanoparticles loaded with ciprofloxacin hydrochloride in order to enhance the permeability of drug and for the release of drug over a period of 24 hrs. The nanoparticles were formulated by ionic gelation method using chitosan as a polymer and TPP as a cross linking agent. The compatibility of drug and polymer is studied by using FTIR spectroscopy and DSC method. There was no interaction observed by UV and FTIR study. The six different batches were prepared using different polymer and drug ratio. The fourth batch (N4) shows best results as compared to others which was used for further investigations. The formulation was then optimized for its particle size, zeta potential, morphology, drug content, drug entrapment efficiency, drug loading capacity and in-vitro permeation. TEM study reveals that the nanoparticles are spherical in shape and also confirms the size below 500nm. Drug release studies shows that nanoparticles could release drug for 24 hrs and follows zero order kinetics. From DSC analysis it was found that the drug was effectively encapsulated inside the chitosan nanoparticles. Finally, it was concluded that the penetration of ciprofloxacin hydrochloride was enhanced after loading it into chitosan nanoparticles and also the drug was release over 24 hrs.

Keywords: Nanoparticles, Ciprofloxacin Hydrochloride, Chitosan, Carbopol 934
FORMULATION AND EVALUATION OF DISPERSIBLE PELLETS OF LAGENARIA SICERARIA
Authors: Dudhamal S S , Kawtikwar P S , Nagoba S N 
Published: November 2018

Lagenaria siceraria (Bottle gourd) is a common name in every household. Its medicinal values were identified many years ago, and still people use this plant for many disorders. Extrusion spheronization technique was employed for preparation of the pellets, to study the effect of crosscarmellose sodium, on it. The pellets were prepared by use of combination of Avicel PH 101 and lactose that indicated good flow properties. The superdisintegrant used was crosscarmellose sodium between concentration 2 to 8%, to study the effect of it on the pellets. The superdisintegrant showed low disintegration time at low concentration, while as the concentration of it increased, it extended the disintegration time. Thus, optimum concentration needs to be designed for successful formulation. Batch D3 of 6% crosscarmellose sodium concentration showed the requisite characteristic in terms of all the evaluation parameters, with DT up to 50 to 55 seconds. Thus, use of this superdisintegrant alone, but in low concentration, can be helpful, or else combination of this with other superdisintegrants can be approached, or else new superdisintegrants can be tried. Thus, the study indicated the effect of superdisintegrant for formulation of dispersible pellets.
Keywords: Extrusion-Spheronization, Crosscarmellose sodium, Lagenaria siceraria, Pellets
A REVIEW ON THE EFFECTIVENESS OF CURRENT APPROACHES TO STRESS MANAGEMENT
Authors: Dubey Chetan Kumar , Chaturvedi Sarika , Chaturvedi Shilpi 
Published: November 2018

Stress is your body’s way of responding to any kind of demand or threat. When you sense danger—whether it’s real or imagined—the body's defenses kick into high gear in a rapid, automatic process known as the “fight-or-flight” reaction or the "stress response. The stress response is the body’s way of protecting you. When working properly, it helps you stay focused, energetic and alert. In emergency situations, stress can save your life—giving you extra strength to defend yourself, for example, or spurring you to slam on the brakes to avoid an accident. Stress can also help you rise to meet challenges. It’s what keeps you on your toes during a presentation at work, sharpens your concentration when you’re attempting the game-winning free throw, or drives you to study for an exam when you'd rather be watching TV. But beyond a certain point, stress stops being helpful and starts causing major damage to your health, your mood, your productivity, your relationships, and your quality of life.
Keywords- Stress, psychology of stress, HPA axis, ACTH
Significance of Doshas in Management of various Disease
Authors: Asthana Alok Kumar , Asthana Monika Monika , Sahu Renu 
Published: November 2018

In Ayurveda, the span of life is described to be determined on the basis of nature of the physique, type of constitution. The utility of Ayurveda is to help maintain the health of a healthy individual and cure of disease of a patient. In our ancient text, the pathogenic factor in the body are Vayu, Pitta and Kapha, while those in the mind are Rajas and Tamas. Out of three. qualities (Gunas) of mind viz., Sattva, Rajas, Tamas, it is only the latter two that cause vitiation of the mind, the former one being non-pathogenic.In other words, Vayu, pitta and Kapha are, somatic Doshas and Rajas and Tamas are the psychic ones. These three Doshas when vitiated harmful to our Dhatu (tissue) and donate life in an unvitiated state, which means helping in the acquisition of health.so for the healthy life equilibrium of Doshas is mandatory.
KEY WORDS: Vata, moksha, pitta, kapha, shleshma.