bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using the Total Apparent Spacing Approach to Optimize Foundation Drain Orientations
Authors: Roman William M. , Berezniak John N. 
Published: November 2024

ABSTRACT
Design of foundation drain holes in bedrock where fractures control the permeability may be optimized based on the discontinuity pattern, specifically the spacing and orientation of the predominant discontinuity sets. When suitable representative outcrops are available, either naturally or by means of excavation, joint spacing and orientation can be measured directly by traditional methods using a measuring tape and compass or pocket transit or newer methods using computer software to measure virtual joint surfaces within a digital terrain model developed from digital photogrammetry or light detection and ranging (LiDAR) surveys. When suitable outcrops are not available, joint spacing and orientation can be measured using oriented core drilling techniques or downhole imaging tools (e.g., optical and acoustic sondes) that provide digital images of the borehole wall. With an understanding of the bedrock jointing pattern obtained from one or more of the above methods, the total apparent spacing (TAS) approach can be used to optimize the orientation of drain holes. The TAS approach employs the vector dot product formula to minimize the total apparent spacing between discontinuities and maximize the number of discontinuities intercepted by the drain hole. The TAS approach was used to optimize the orientation of foundation drain holes during rehabilitation of the Gilboa Dam in Schoharie County, NY. The TAS approach has other applications, e.g., optimizing the orientation of exploratory core holes to collect discontinuity data or the orientation of grout holes for foundation grouting.
Kulisy wyboru bp. Józefa Gawliny na Protektora Wychodźstwa Polskiego (1949)
Authors: Kłakus Michał 
Published: November 2024

Po 1945 r. Kościół w Polsce stanął przed nowymi wyzwaniami. Do najważniejszych należała organizacja życia religijnego w zmienionych warunkach politycznych, jak również zachowanie polskiego wychodźstwa katolickiego jako nierozerwalnej części Kościoła polskiego. Zwłaszcza że było ono zasadniczo antykomunistyczne. Od 1931 r. Protektorem Polaków za granicą był Prymas Polski. Po drugiej wojnie światowej nie mógł on swobodnie wyjeżdżać za granicę. Szczególnym uznaniem wśród Polonii cieszył się biskup polowy Józef Gawlina. Ostatni przedwojenny biskup polowy był dobrze wykształcony, łatwo nawiązywał kontakt z ludźmi, odbywał liczne podróże zagraniczne, swobodnie posługiwał się kilkoma językami. Celem niniejszego artykułu jest przedstawienie kulisów jego wyboru na Protektora Wychodźstwa Polskiego (1949) ze szczególnym uwzględnieniem zamierzeń i zabiegów przełożonych bpa Gawliny oraz rządów warszawskiego i na Wychodźstwie.
Early Detection of Preeclampsia in Low-Resource Setting: Examining Risk Factors, Mean Arterial Blood Pressure (Map), Body Mass Index (Bmi), and Urine Protein at Public Primary Health Care
Authors: Febriza Ami , Nurdiana  , Erni  , Nadhiroh A’im Matun 
Published: November 2024

Background and Aim:
Preeclampsia is a significant threat to maternal health worldwide,
leading to both infant and maternal morbidity or mortality. It also increases the risk of premature
births and cardiovascular disease in affected mothers. Early risk assessments for preeclampsia in
pregnant women are essential. Our study aims to identify a method for early detection of
preeclampsia in low-resource areas by using tools such as risk assessment, BMI measurements,
MAP, and urine protein tests at Public Primary Health Care facilities.

Methods:
A cross-sectional study with a correlational analytic design was employed among 115 pregnant
women from Public Primary Health Care facilities in South Sulawesi, Indonesia. Data collection
included a questionnaire using a demographic questionnaire, maternal history of disease, and direct
measurement for BMI, MAP, and urine protein. The statistical analysis used the Fisher exact test to
test the difference in proportion among categorical data, and the Pearson r correlation was used to estimate
the prediction of BMI with maternal blood pressure and MAP during pregnancy.

Results:
Our study found that increased BMI in pregnant women is associated with elevated diastolic,
systolic, and mean arterial blood pressure (MAP) (p-value 0.001). Additionally, we discovered
significant correlations between age group, chronic hypertension, maternal preeclampsia history,
and family history of preeclampsia with preeclampsia (p-value < 0.05).

Conclusion:
This study identified several contributory factors that are significantly associated with
preeclampsia, including maternal age, a history of preeclampsia, a history of chronic hypertension,
body mass index, and MAP.
Box-bhenken Design Combined with 3D Surface Methodology for Optimization of an Eco-friendly HPLC Method to Determine Venetoclax in Human Plasma, and its Bioanalytical Method Validation According to ICH M10 Guideline
Authors: Özcan Saniye , Elriş Abeer , Altun Mazlum Akif , Levent Serkan , Can Nafiz Öncü 
Published: November 2024

Aims:
Venetoclax is a selective inhibitor of the prosurvival protein BCL-2 approved by
the Food Drug Administration in 2016, restoring the apoptic ability of malignant cells. In this study,
a fast, highly accurate and precise HPLC method was developed for the analysis of Venetoclax in
human plasma.

Methods:
The optimization of the method was investigated according to Box-Bhenken Design combined
with 3D surface methodology. The chromatographic separation was performed in gradient
mode with an Ascentis Express C8 column (2.7 μm, 4.6 mm × 10 cm). Agomelatine was used as an
internal standard to increase accuracy. The method was completely validated according to ICH
guideline M10 bioanalytical method validation. Additionally, the greenness of the method was scaled
with NEMI, Analytical Ecoscale, AGREE, and GAPI greenness metrics.

Results:
The method was linear in the range of 1.67-12.50 μg/mL with a calculated R2 of 0.99; LOD
and LOQ were 0.34 μg/mL and 1.02 μg/mL, respectively. The recovery was in the range of 102.6%
to 99.08%, and with an RSD% of less than 1.00%. The analytical eco scale and AGREE score of the
current method were 85 and 0.55, respectively.

Conclusion:
The approach that was developed herein exhibits green, rapidity, high levels of accuracy
and precision, cost-effectiveness, and ease of use in the context of clinical and pharmacokinetic
investigations.
Quantitative Impact of Traditional Open Surgery and Minimally Invasive Surgery on Patients’ First-Night Sleep Status in the Intensive Care Unit: Prospective Cohort Study
Authors: Shang Chen , Yang Ya , He Chengcheng , Feng Junqi , Li Yan , Tian Meimei , Zhao Zhanqi , Gao Yuan , Li Zhe 
Published: November 2024

Background
The sleep status of patients in the surgical intensive care unit (ICU) significantly impacts their recoveries. However, the effects of surgical procedures on sleep are rarely studied.

Objective
This study aimed to investigate quantitatively the impact of traditional open surgery (TOS) versus minimally invasive surgery (MIS) on patients’ first-night sleep status in a surgical ICU.

Methods
Patients transferred to the ICU after surgery were prospectively screened. The sleep status on the night of surgery was assessed by the patient- and nurse-completed Richards-Campbell Sleep Questionnaire (RCSQ) and Huawei wearable sleep monitoring wristband. Surgical types and sleep parameters were analyzed.

Results
A total of 61 patients were enrolled. Compared to patients in the TOS group, patients in the MIS group had a higher nurse-RCSQ score (mean 60.9, SD 16.9 vs mean 51.2, SD 17.3; P=.03), self-RCSQ score (mean 58.6, SD 16.2 vs mean 49.5, SD 14.8; P=.03), and Huawei sleep score (mean 77.9, SD 4.5 vs mean 68.6, SD 11.1; P<.001). Quantitative sleep analysis of Huawei wearable data showed a longer total sleep period (mean 503.0, SD 91.4 vs mean 437.9, SD 144.0 min; P=.04), longer rapid eye movement sleep period (mean 81.0, 52.1 vs mean 55.8, SD 44.5 min; P=.047), and higher deep sleep continuity score (mean 56.4, SD 7.0 vs mean 47.5, SD 12.1; P=.001) in the MIS group.

Conclusions
MIS, compared to TOS, contributed to higher sleep quality for patients in the ICU after surgery.
Indigenous Parents’ Perspectives of Factors That Facilitate or Impede Engagement in Internet-Based Parenting Support Programs: Interpretive Description Study
Authors: Butt Michelle L , Willett Ysabella Jayne , Miller Vicky , Jacobs Brenda , Ferron Era Mae , Wright Amy L 
Published: November 2024

Background
Parenting support programs enhance parents’ health and their child’s development. The COVID-19 pandemic necessitated the delivery of these programs over the internet. After the pandemic, internet-based programs are still preferred by some.

Objective
We aimed to understand Indigenous parents’ experiences engaging in internet-based parenting support programs; thus, an interpretive description study was conducted.

Methods
A total of 20 Indigenous (female, male, and Two-Spirit) parents of children aged <5 years participated in semistructured interviews; data underwent collaborative thematic analysis with Indigenous community partners informed by the Two-Eyed Seeing framework and ethical space.

Results
Parents’ experiences were classified into five themes: (1) Purpose: Program Delivery and Content, (2) Belonging: Building Relationships and Connections, (3) Hope: Cultural Connection, (4) Meaning: New or Improved Parenting Skills and Mental Wellness, and (5) Recommendations for Organizations.

Conclusions
The study findings can inform internet-based parenting program delivery to enhance engagement for Indigenous families.
Relaciones entre perfeccionismo disfuncional y estrés escolar en estudiantes de nivel primario de Posadas (Argentina)
Authors: Chemisquy Sonia Noemí , Arévalo Luana Natahela , Penz Picaza Milagros Mercedes 
Published: November 2024

Aunque es conocido que el perfeccionismo desadaptativo tiene consecuencias negativas en la vida académica, hasta el momento no se hallaron trabajos científicos que estudien el estrés escolar en relación con las tres dimensiones del perfeccionismo multidimensional (i. e., autorientado, socialmente prescrito y orientado a otros). El objetivo de este trabajo fue analizar el rol predictor del perfeccionismo disfuncional en el estrés escolar de estudiantes de nivel primario y valorar la contribución diferencial de cada una de sus dimensiones. Se realizó un estudio cuantitativo, transversal y correlacional con n = 226 estudiantes de escuelas primarias de la ciudad de Posadas, Argentina. Los resultados sugieren que el perfeccionismo predice el estrés escolar en un 31.9 %, sobre todo en las dimensiones autorientada y socialmente prescrita. En el análisis de regresión multivariada, el perfeccionismo autorientado contribuyó al estrés emocional y a la tensión interpersonal, el perfeccionismo socialmente prescrito predijo las tres dimensiones del estrés escolar, mientras que el perfeccionismo orientado a otros solo predijo la tensión interpersonal. Estos resultados son acordes al modelo teórico de base y aportan información relevante para profundizar el conocimiento de la dinámica del perfeccionismo infantil en el nivel primario de la escuela.
Conflictos internos municipales en la provincia de Córdoba = Internal municipal conflicts in the province of Córdoba
Authors: Tissera Federico 
Published: November 2024

En el presente estudio se aborda la temática relativa a los conflictos internos de poderes en el ámbito municipal, suscitados entre los organismos que integran el gobierno local. Se inicia con un
tratamiento aspectos preliminares relativos a la organización estadual bajo la que se establecen los parámetros bajo los que se desenvuelven institucionalmente los municipios en la Provincia de Córdoba.
Tras ello, se analiza, en el marco de nuestra legislación provincial, al conflicto de poderes como género, para luego abordar específicamente los conflictos internos municipales, precisando los aspectos sustanciales que los definen y las diversas modalidades que pueden adoptar en la realidad jurídico- política local. Finalmente, se estudian las cuestiones procesales que los regulan, cuál es el procedimiento necesario para encauzarlos, y cuáles son las posibles impugnaciones que pueden articularse una vez sentenciado el asunto.

ABSTRACT: This study addresses the issue of internal power conflicts in the municipal sphere, arising between the agencies that make up the local government. It begins with a treatment of preliminary aspects related to the state organization under which the parameters are established under which the municipalities in the Province of Córdoba develop institutionally. After that, it is analyzed, within the framework of our provincial legislation, the conflict of powers as a gender, to thenspecifically address internal municipal conflicts, specifying the substantial aspects that define them and the various modalities that they can adopt in the legal-political reality. local. Finally, the procedural issues that regulate them are studied, what is the necessary procedure to channel them, and what are the possible challenges that can be articulated once the matter has been sentenced.
Osteoprotegerin, Osteopontin, and Osteocalcin Are Associated With Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL
Authors: Maddaloni Ernesto , Nguyen Maggie , Shah Svati H. , Holman Rury R. 
Published: November 2024

OBJECTIVE
To evaluate the association of four bone metabolism biomarkers (osteoprotegerin, osteopontin, sclerostin, and osteocalcin) with cardiovascular events in people with type 2 diabetes (T2D).

RESEARCH DESIGN AND METHODS
The Exenatide Study of Cardiovascular Event Lowering (EXSCEL) was a randomized clinical trial evaluating the cardiovascular (CV) safety and efficacy of once-weekly exenatide for patients with T2D. Candidate biomarker data were selected from proteomic profiling performed at baseline and 12 months after randomization samples by SomaScan assay in 5,473 trial participants. The primary composite outcome was the first occurrence of CV death, nonfatal myocardial infarction, or nonfatal stroke (major cardiovascular events [MACE]). Cox proportional hazards models controlling for confounders were used for time-to-event analyses to calculate hazard ratios (HRs) with 95% CI for a 1 SD increase in the biomarker concentrations.

RESULTS
The primary outcome occurred in 813 participants (14.9%). Higher levels of osteoprotegerin (HR 1.11; 95% CI 1.03–1.20; P = 0.0047) and osteopontin (HR 1.10; 95% CI 1.02–1.18; P = 0.0095) were associated with an increased risk of MACE. The addition of osteoprotegerin and osteopontin to a clinical predictive model containing traditional CV risk factors provided minimal incremental value for MACE prediction (C-index 0.629 vs. 0.638; likelihood ratio test P &lt; 0.001). Osteocalcin and sclerostin were not associated with MACE. Osteocalcin had a nonlinear association with all-cause death and with CV death.

CONCLUSIONS
Higher levels of osteoprotegerin and osteopontin are associated with an increased risk of CV events in people with T2D, supporting the hypothesis that pathways involved in bone metabolism play a role in CV disease.
Application of Foam Mat Drying Method for the Production of Instant Red Ginger Powder using Microwave
Authors: Purbasari Dian , Lestari Wahyu Winda , Sutarsi Sutarsi , Lestari Ning Puji , Taruna Iwan 
Published: November 2024

Drying red ginger juice into instant powder is done to extend the shelf life of ginger which easily undergoes physical and chemical changes. This research aims to determine the characteristics of red ginger juice powder resulting from the foam mat drying method using a microwave. This research used a Completely Randomized Design method with two factors. Factor I is the microwave oven power (341 W, 364 W, and 466 W). Factor II is the concentration of maltodextrin (10%, 15%, and 20%). Data analysis used a two-way ANOVA test and continued with the DMRT test and scoring test. The results of the powder characteristics produce FM values (5.01 – 5.55); D (0.14 – 0.21 mm); yield (6.70 – 7.11%); powder moisture content (3.26 – 6.37%); brightness level (71.10 – 84.97); redness level (4.14 – 9.13); yellowness level (16.35 – 25.67); water absorption capacity (32.76 – 53.11) and solubility (99.93 – 99.99). Differences in microwave power affect the parameters of degree of fineness (FM), grain size (D), water content, brightness level (L), redness level (a), yellowness level (b), water absorption capacity, and solubility power. Differences in maltodextrin concentration affect the parameters of redness level and solubility. The best combination treatment is 343 W microwave power treatment with a maltodextrin concentration of 20%. Keywords: Drying, Foam mat drying, Microwave, Powder, Red ginger.
Sensory Study and Financial Feasibility Analysis of Alpinia galangal Fish Shredded Products
Authors: Alamsyah Fadli , Sartika Dewi , Astuti Sussi , Satyajaya Wisnu , Hidayati Sri , Ayunisa Puan Mutia 
Published: November 2024

Spices have always been a part of Indonesia's culinary culture. One of the spices that has high economic value and efficacy is galangal. Therefore, testing of bioactive compounds and the effect of making shredded spice fish with the addition of various concentrations of galangal needs to be further investigated in terms of sensory quality and financial feasibility. This study aims to determine the bioactive components in galangal spice, determine the best concentration of galangal addition in shredded spiced fish products, and determine the financial feasibility. The research was conducted by making galangal spice and shredded spiced fish at IDAEZ Group MSMEs. Subsequently, the galangal spice was tested for bioactive compound (GC-MS) and then, sensory tests were carried out on shredded fish spices mixed with galangal spices (1%, 2%, 3%). After that, the financial feasibility analysis was calculated. The results obtained showed that there were four main components in galangal spice, such as 5-Eicosenen, (E)-, n-Hexadecanoic acid, oleic acid, and 9-Octadecenoic acid (Z)-, oxiranylmethyl ester. Meanwhile, the best concentration of shredded spice fish was found in treatment P3 (addition of 3% galangal). Lastly, the shredded spice fish was found to be viable with an income of IDR 427,547 per production. Keywords: Financial feasibility, GC-MS, Galangal, Sensory.
Study of Types of Packaging Materials and Storage Temperature on The Quality of Soybean Seeds (Glycine max L. Merrill)
Authors: Ma'sumah Ma'sumah , Moeldjani Ida Retno , Sutini Sutini 
Published: November 2024

The quality of soybean seeds, encompassing physical, physiological, and chemical attributes, is crucial for successful plant growth and yield. Effective seed storage is vital in maintaining seed viability, growth capacity, and adaptability, especially amid global challenges like climate change and rising food demand. This research aimed to identify the optimal packaging material and storage temperature to preserve soybean seed quality. Using a Split Plot Design with two factors and three replications, the study examined four storage temperatures (S0: 27.1°C, S1: 7-10°C, S2: 17-19°C, S3: 20-25°C) and three packaging types (K1: plastic-coated sack, K2: PE plastic, K3: aluminum foil). Results indicated that seeds stored at 27.1°C in plastic-coated sacks experienced increased moisture, reduced vigor, slower growth, lower germination, and altered protein and fat content. Conversely, PE plastic and aluminum foil packaging maintained seed quality over three months. All packaging types effectively preserved seed quality at cooler temperatures (7-25°C). This study underscores the importance of optimal storage conditions for sustainable soybean seed availability. Keywords: Packaging, Seed Quality, Soybean Seeds, Storage, Temperature.
Poesía y mecánica en el siglo XIV. I- Los relojes en la Divina Commedia
Authors: Ruvituso Marcos 
Published: November 2024

Múltiples espacios circulares aparecen en el itinerario de la Commedia, desde los inmensos giros y la música de las esferas celestiales hasta las pequeñas ruedas de dos relojes mecánicos. En el primer reloj (Par. X 139-148) reaparecen las relaciones entre ruedas y música en un mecanismo provisto de sonería horaria o de despertador, que se mueve y suena como una rueda celestial, "in tempra". En la época de Dante los relojes mecánicos ya eran artefactos conocidos y las fuentes más antiguas suelen destacar la capacidad de producir regularmente sonidos musicales. En el segundo reloj (Par. XXIV 10-18) las ruedas que se asimilan con rondas de almas de santos giran acordes con una función precisa. El movimiento de la sonería horaria es el que se adapta mejor a la descripción de las ruedas del segundo reloj. Los primeros relojes mecánicos respondieron históricamente a la distinción entre las horas canónicas y las del trabajo urbano, pero también fueron considerados instrumentos con valor simbólico y solo posteriormente modelos mecánicos del universo. Dante es uno de los primeros en presentar los relojes como artefactos que imitan con ruedas mecánicas, movimientos y sonidos de las esferas celestiales, como lo indica la repetición de la expresión "in tempra".
Crónica
Authors: Grimozzi Chiara , Cairo María Emilia , Zarza Mariano 
Published: November 2024

IX Coloquio Internacional “Pensar la Antigüedad en clave contemporánea: enfoques interdisciplinarios y nuevos paradigmas”. La Plata, 21 a 23 de junio de 2023. VI Congreso Internacional de Retórica e Interdisciplina – VII Coloquio Nacional de Retórica “La retórica y el poder”. Mendoza, 13 a 15 de septiembre de 2023. XI Jornadas de Estudios Clásicos y Medievales “Diálogos Culturales”. Juego e imaginación en la Antigüedad y en la Edad Media. Ensenada, 1 a 3 de noviembre de 2023.
Minecraft as an Educational Tool Before, During, and After the Pandemic: A Case Study Research Project
Authors: Cigognini Elisabetta M. , Nardi Andrea 
Published: November 2024

Abstract
This study aims to explore the educational potential of Minecraft as a learning environment that supports active teaching methods, especially in remote contexts. It presents the experience of remote laboratory teaching within the MineClass project conducted from 2018 to 2021, addressing the challenges posed by the reduction of in-person and online collaborative activities during the pandemic. The research combines case studies, qualitative and quantitative surveys, and interviews with teachers and students who experienced the educational use of Minecraft before, during, and after the COVID-19 pandemic. The results presented here are based on questionnaires administered to a sample of teachers (n = 237) and students (n = 2,264) to investigate the advantages and limitations of the educational use of the game and differences in terms of student satisfaction, perceived self-efficacy, peer collaboration, school level, and gender of participants. The results reveal that many teachers continued to use Minecraft for distance learning even after the conclusion of the project. Teachers reported a positive impact of the experimentation in terms of student engagement, interest, enthusiasm, and knowledge and skills acquisition. Students provided very positive feedback on overcoming social isolation through immersive learning, with increased motivation, engagement, and the development of cross-cutting competencies.