bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond Simple AB Diblock Copolymers: Application of Bifunctional and Trifunctional RAFT Agents to PISA in Water
Authors: Mellot Gaëlle , Beaunier Patricia , Guigner Jean‐Michel , Bouteiller Laurent , Rieger Jutta , Stoffelbach François 
Published: June 2018

AbstractThe influence of the macromolecular reversible addition‐fragmentation chain transfer (macro‐RAFT) agent architecture on the morphology of the self‐assemblies obtained by aqueous RAFT dispersion polymerization in polymerization‐induced self‐assembly (PISA) is studied by comparing amphiphilic AB diblock, (AB)2 triblock, and triarm star‐shaped (AB)3 copolymers, constituted of N,N‐dimethylacrylamide (DMAc = A) and diacetone acrylamide (DAAm = B). Symmetrical triarm (AB)3 copolymers could be synthesized for the first time in a PISA process. Spheres and higher order morphologies, such as worms or vesicles, could be obtained for all types of architectures and the parameters that determine their formation have been studied. In particular, we found that the total DPn of the PDMAc and the PDAAm segments, i.e., the same overall molar mass, at the same Mn(PDMAc)/Mn(PDAAm) ratio, rather than the individual length of the arms determined the morphologies for the linear (AB)2 and star shaped (AB)3 copolymers obtained by using the bi‐ and trifunctional macro‐RAFT agents.
A relative ranking with multidimensional indicators. Application to the Spanish banking sector
Authors: Rubiales Victoriana , Monroy Luisa , Mármol Amparo M. 
Published: June 2018

AbstractIn this paper, we propose a procedure to determine an overall ranking of a group of entities when the information available on the entities consists of the values of a set of indicators, which have a multidimensional nature. The multiplicity of the data available for each indicator may represent the valuation of the indicator in different scenarios, in different periods of time, or the assessment of various agents on the value of the indicator. A multicriteria treatment allows us to maintain the multidimensional nature of each indicator in order to avoid the possibility that some relevant information may be lost, and it permits the inclusion of partial information about the importance of the indicators. The proposal consists of a recursive procedure such that, at each stage, the resolution of a multiciteria linear problem yields a set of valuation vectors for each entity and subsequently, by using a distance‐based method, an overall ranking that synthesises the information given by these valuation vectors is obtained. The applicability of the proposed procedure is shown with the construction of the ranking of the main banks of the Spanish banking sector from a set of financial indicators.
A Simple Monte Carlo Method for Modeling Arborescent Polymer Production in Continuous Stirred Tank Reactor
Authors: Zhao Yutian R. , Buren Bradley D. , Puskas Judit E. , McAuley Kimberley B. 
Published: June 2018

AbstractA dynamic model is developed to simulate arborescent polyisobutylene (arbPIB) production via self‐condensing vinyl copolymerization in a continuous stirred tank reactor (CSTR). A kinetic Monte Carlo algorithm is proposed that discretizes inflow and outflow separately from reaction steps. The model predicts dynamic changes in monomer and inimer (IM) concentrations, as well as , , and molecular weight distribution (MWD). The CSTR produces arbPIB with broader MWD, compared to a batch reactor using the same recipe and operation time. Predictions of and agree with a previous deterministic model. CSTR operation with high [IM] is unstable because large molecules tend to become even larger as time increases.
Accuracy of electronic health record data for the diagnosis of chronic obstructive pulmonary disease in persons living with HIV and uninfected persons
Authors: Crothers Kristina , Rodriguez Carla V. , Nance Robin M. , Akgun Kathleen , Shahrir Shahida , Kim Joon , W. Soo Hoo Guy , Sharafkhaneh Amir , Crane Heidi M. , Justice Amy C. 
Published: June 2018

AbstractPurposeNo prior studies have addressed the performance of electronic health record (EHR) data to diagnose chronic obstructive pulmonary disease (COPD) in people living with HIV (PLWH), in whom COPD could be more likely to be underdiagnosed or misdiagnosed, given the higher frequency of respiratory symptoms and smoking compared with HIV‐uninfected (uninfected) persons.MethodsWe determined whether EHR data could improve accuracy of ICD‐9 codes to define COPD when compared with spirometry in PLWH vs uninfected, and quantified level of discrimination using the area under the receiver‐operating curve (AUC). The development cohort consisted of 350 participants who completed research spirometry in the Examinations of HIV Associated Lung Emphysema (EXHALE) study, a pulmonary substudy of the Veterans Aging Cohort Study. Results were externally validated in 294 PLWH who performed spirometry for clinical indications from the University of Washington (UW) site of the Centers for AIDS Research Network of Integrated Clinical Systems cohort.ResultsICD‐9 codes performed similarly by HIV status, but alone were poor at discriminating cases from non‐cases of COPD when compared with spirometry (AUC 0.633 in EXHALE; 0.651 in the UW cohort). However, algorithms that combined ICD‐9 codes with other clinical variables available in the EHR—age, smoking, and COPD inhalers—improved discrimination and performed similarly in EXHALE (AUC 0.771) and UW (AUC 0.734).ConclusionsThese data support that EHR data in combination with ICD‐9 codes have moderately good accuracy to identify COPD when spirometry data are not available, and perform similarly in PLWH and uninfected individuals.
Proteomic Analysis of Synaptoneurosomes Highlights the Relevant Role of Local Translation in the Hippocampus
Authors: Benito Itziar , Casañas Juan José , Montesinos María Luz 
Published: June 2018

AbstractSeveral proteomic analyses have been performed on synaptic fractions isolated from cortex or even total brain, resulting in preparations with a high synaptic heterogeneity and complexity. Synaptoneurosomes (SNs) are subcellular membranous elements that contain sealed pre‐ and post‐synaptic components. They are obtained by subcellular fractionation of brain homogenates and serve as a suitable model to study many aspects of the synapse physiology. Here the proteomic content of SNs isolated from hippocampus of adult mice, a brain region involved in memory that presents lower synaptic heterogeneity than cortex, is reported. Interestingly, in addition to pre‐ and post‐synaptic proteins, proteins involved in RNA binding and translation are overrepresented in this preparation. These results validate the protocol previously reported for SNs isolation, and, as reported by other authors, highlight the relevance of local synaptic translation for hippocampal physiology.
Teleoperated tubular continuum robots for transoral surgery – feasibility in a porcine larynx model
Authors: Friedrich D.T. , Modes V. , Hoffmann T.K. , Greve J. , Schuler P.J. , Burgner‐Kahrs J. 
Published: June 2018

AbstractBackgroundEvidence suggests that transoral robot‐assisted surgery is becoming increasingly common, yet current systems are incapable of sufficiently reaching the glottis or subglottic areas. This paper presents a teleoperated tubular continuum robot prototype for laryngeal surgery in a feasibility study.MethodsA tubular continuum robot prototype is used to perform basic surgical examination in five ex vivo porcine laryngeal specimens. Standard imaging and tooling were integrated and evaluated to improve the system for future application in humans.ResultsAccess to and application of the tubular continuum robot in the porcine larynx is feasible. Visualization of and accessibility to all structures of interest were successfully achieved, and minor surgical procedures such as biopsies could be performed.ConclusionsDespite proven feasibility, there is a need for further improvements. A version with dual robot arms would be essential to realize a pre‐market prototype for further investigation in a human model.
Trust, information sharing and uncertainty: An empirical investigation into their impact on sustainability in service supply chains in the United Arab Emirates
Authors: Khan Mehmood , Hussain Matloub , Papastathopoulos Avraam , Manikas Ioannis 
Published: June 2018

AbstractThe idea of sustainability has yet to enjoy its due share in service supply chains. There has been a dearth of literature in this area, predominantly regarding assessing the impact of collaborative attributes on supply chain sustainability. An integrated supply chain model comprising trust, information sharing and uncertainty practices is proposed here to assess their impact on the sustainability of service supply chains in the United Arab Emirates (UAE). The study conducts a comprehensive literature review to develop constructs and their items. Social exchange theory is used to link these constructs/variables to sustainability. These variables are linked to sustainability through social exchange theory of behaviors. Structural equation modeling is used to test five hypotheses pertaining to the impact of those constructs on sustainability. The results of this study can help managers align and prioritize their investments while targeting sustainability in their partnerships with numerous stakeholders. Several implications and limitations of the study are also outlined at the end of the paper.
Post Modification of Poly Glycidyl Azide with Ionic‐Liquid‐Based Reactive Plasticizer through Catalyst‐Free Click Reaction
Authors: Fareghi‐Alamdari Reza , Jafari Najmeh , Shahidzadeh Mansour , Zekri Negar 
Published: June 2018

AbstractGlycidyl azide polymer (GAP), due to its energy, has found widespread applications in propellants. However, one of the most critical challenges in the propellants is preventing the migration of the plasticizer material from the polymeric matrix. To counter this, a covalent bond was established between GAP and propargyl imidazolium as the reactive plasticizer via click chemistry reaction. Fourier‐transform infrared spectroscopy (FTIR) and 1H NMR analyses were implemented to confirm that the connection has been made properly to minimize the plasticizer migration. Optimization of the amount of the reactive ionic liquid plasticizer in GAP was another issue investigated in this study. Examinations by Differential scanning calorimetry (DSC) analyses, viscometer, and heat of combustion showed that increasing the reactive plasticizer content leads to the lower glass transition temperature, the higher viscosity, and the lower GAP energy. In order to compensate for the lost energy, due to the formation of the covalent bond, a dicyanamide based ionic liquid plasticizer was synthesized as a replacement for the bromide one. It was found that in addition to the reduction of the glass transition temperature (from −50 °C to −59 °C), it was possible to achieve lower viscosity (from 7 Pa.s to 2 Pa.s) and greater propulsion energy (from 19.24 kJ/g to 21.31 kJ/g).
Oxidative stress‐mediated autophagic cell death participates in the neurotoxic effect on SH‐SY5Y cells induced by excessive iodide
Authors: Liu Hongliang , Wang Lingzhi , Zeng Qiang , Zhao Liang , Cui Yushan , Hou Changchun , Zhang Bin , Zhang Zushan , Zhang Shun , Chen Xuemin , Wang Aiguo 
Published: June 2018

AbstractExcessive iodide could induce intellectual damage in children, which has attracted broad attention. To investigate the neurotoxic effect of iodide and its mechanism, a human dopaminergic neuroblastoma cell line (SH‐SY5Y) was treated with different concentrations of potassium iodide (KI). The results showed that excessive iodide could decrease cell viability, reduce glutathione (GSH) and superoxide dismutase (SOD), and increase the degree of autophagy (by changing the cellular ultrastructure and raising the autophagy‐related mRNA and protein expression of LC3, Beclin1, and p62), which were correlated with the immunofluorescence labeling. Furthermore, treatment with the autophagy inhibitor 3‐methyladenine (3MA), antioxidant N‐acetylcysteine (NAC) and 30 mM KI for 24 h was conducted in the following research. 3MA significantly decreased autophagy‐related mRNA and protein expression and improved cell viability, indicating that excess iodide induced autophagic cell death. In addition, oxidative stress regulated autophagy, reflected by the results that NAC decreased the mRNA and protein expression of LC3, Beclin1, and p62. In summary, autophagic cell death mediated by oxidative stress may participate in excessive iodide‐induced SH‐SY5Y cell death.
Structural parameter identification of a 2.4 MW bottom fixed wind turbine by excitation test using active mass damper
Authors: Oh Sho , Ishihara Takeshi 
Published: June 2018

AbstractWhile the structural damping is an important parameter in the seismic resistant design, several problems exist in the current design codes such as that the recommended values vary largely between design codes, and that the second mode damping ratio which is required in the design is usually not described. In order to evaluate the damping ratios for both first and second modes of MW‐size wind turbines, a series of excitation tests using an active mass damper were performed in this study on a 2.4 MW offshore wind turbine. First, the sinusoidal test, which gives accurate and reliable results for linear systems, is performed, and results show that the damping ratio for the fore‐aft first mode is 0.2% and the fore‐aft second mode is 2.4% for the target wind turbine. Next the free decay test, which is applicable to systems with the effect from the aerodynamic damping, is performed, and results show that the damping ratios obtained for the fore‐aft first and second mode are similar to those from the sinusoidal test. The damping ratio is 1.2% for the side‐side first mode and 3.2% for the side‐side second mode. Finally, an empirical formula for the damping ratios of first mode is proposed for wind turbines with steel towers using the results from the previous researches and the excitation tests in this study.
Possible mechanisms for fog formation over Borg El Arab airport, Egypt
Authors: Sayad Tarek , Morsy Mostafa 
Published: June 2018

AbstractThe main aim of this study is to identify the causes of fog formation over Borg El Arab International Airport in Egypt. The frequency of fog at this location was studied for the period 1990–2010 using a variety of statistical techniques. The relationships between fog and different meteorological factors were also studied alongside fog occurrence frequency data to determine the mechanisms and conditions which are most likely to result in the type of fog observed at the study site. Hourly ground observations of the visibility and other meteorological parameters for foggy days at the site were analysed for the period of study. The results show that the maximum frequency of fog events occurs during winter and autumn months, with the highest daily frequency in November and highest hourly frequency in December. Most of the fog events lasted for a considerable period of time, with a maximum observed event duration of 13 h in January 2007. The fog events over the study area tend to occur during the early morning, between 0100 h and 0700LT (utc + 02 h), with a peak at 0500 h. Over the period of study there is a decreasing trend in annual fog frequency over the study area. Moderate fog is the most commonly observed category of fog event for all seasons (and it occurs most frequently in November and December), while severe fog is the last commonly observed category for all seasons. Fog requires stability in the lower layer of the atmosphere, and it forms over the study area when there is a high pressure of between 1010 and 1021 hPa, a low wind speed of less than 3 ms−1, predominately northeasterly, southwesterly, southeasterly or northerly wind directions, relative humidity higher than 85%, and a dew‐point deficit of less than 3 degC. Therefore, severe, moderate, and weak fog events are highly negatively correlated with wind speed (−0.82, −0.81 and − 0.81, respectively) and dew‐point deficit (−0.69, −0.71 and − 0.66), but are positively correlated with relative humidity (0.76, 0.84 and 0.79).
Mapping of the available standards against the regulatory needs for nanomedicines
Authors: Halamoda‐Kenzaoui Blanka , Holzwarth Uwe , Roebben Gert , Bogni Alessia , Bremer‐Hoffmann Susanne 
Published: June 2018

Appropriate documentary standards and reference materials are crucial building blocks for the development of innovative products. In order to support the emerging sector of nanomedicine, relevant standards must be identified and/or developed before the products will enter into the regulatory approval process. The anticipation of standardization needs requires a good understanding on the regulatory information requirements that can be triggered by the particularities of nanomedicines. However, robust datasets allowing firm conclusions on regulatory demands are not yet available due to a lack of regulatory experience with innovative products. Such a catch‐22 situation can only be advanced in an iterative process by monitoring continuously the scientific evidence and by promoting intensive knowledge exchange between all involved stakeholders. In this study, we have compiled information requirements released by regulatory scientists so far and mapped it against available standards that could be of relevance for nanomedicines. Our gap analysis clearly demonstrated that for some endpoints such as drug release/loading and the interaction of nanomedicines with the immune system no standards are available so far. The emerging nanomedicine sector could benefit from cross‐sector collaboration and review the suitability of standards that have been developed for nanomaterials used for other industrial applications. Only a concerted action of all parties can lead to a smooth translation of nanomedicines to clinical application and to the market. This is in particular important because nanotechnology‐based drug delivery systems are key for the development and implementation of personalized medicine.This article is characterized under:Toxicology and Regulatory Issues in Nanomedicine > Regulatory and Policy Issues in Nanomedicine
Healthcare personnel vaccination policies in michigan long-term care facilities
Authors: Kimmins Lynsey M. , Bramer Cristi A. , Chandler Jacklyn L. , Hart Adam L. 
Published: June 2018

AbstractOf the 461 licensed long-term care facilities (LTCFs) in Michigan, 129 responded to the first survey of LTCF healthcare personnel (HCP) immunization policies, coverage estimates, and perceived barriers to vaccination. Survey results suggest opportunities to improve HCP vaccination through polices, education, barrier removal, and HCP immunity status tracking in licensed LTCFs in Michigan.
The Japanese food score and risk of all-cause, CVD and cancer mortality: the Japan Collaborative Cohort Study
Authors: Okada Emiko , Nakamura Koshi , Ukawa Shigekazu , Wakai Kenji , Date Chigusa , Iso Hiroyasu , Tamakoshi Akiko 
Published: June 2018

AbstractFew studies have reported the association between the Japanese diet as food score and mortality. This study aimed to investigate adherence to the Japanese food score associated with all-cause, CVD and cancer mortality. A total of 58 767 (23 162 men and 34 232 women) Japanese participants aged 40–79 years, who enrolled in the Japan Collaborative Cohort Study between 1988 and 1990, were included. The Japanese food score was derived from the components of seven food groups (beans and bean products, fresh fishes, vegetables, Japanese pickles, fungi, seaweeds and fruits) based on the FFQ. The total score ranged from 0 to 7, and participants were divided into five categories based on scores (0–2, 3, 4, 5 and 6–7). Hazard ratios (HR) and 95 % CI for all-cause, CVD and cancer mortality based on sex were estimated using Cox proportional models. During the follow-up period until 2009, 11 692 participants with all-cause, 3408 with CVD and 4247 with cancer died. The multivariable HR in the 6–7 and 0–2 Japanese food score groups were 0·93 (95 % CI 0·86, 1·01) in men and 0·82 (95 % CI 0·75, 0·90) in women for all-cause mortality and 0·89 (95 % CI 0·76, 1·04) in men and 0·66 (95 % CI 0·56, 0·77) in women for CVD mortality. Our findings suggest that adherence to the Japanese food score consisting of food combinations characterised by a Japanese diet may help in preventing all-cause and CVD mortality, especially in women.
ON THE CONJUGACY PROBLEM IN CERTAIN METABELIAN GROUPS
Authors: GRYAK JONATHAN , KAHROBAEI DELARAM , MARTINEZ-PEREZ CONCHITA 
Published: June 2018

AbstractWe analyze the computational complexity of an algorithm to solve the conjugacy search problem in a certain family of metabelian groups. We prove that in general the time complexity of the conjugacy search problem for these groups is at most exponential. For a subfamily of groups, we prove that the conjugacy search problem is polynomial. We also show that for a different subfamily the conjugacy search problem reduces to the discrete logarithm problem.
EXOTIC FINITE FUNCTORIAL SEMI-NORMS ON SINGULAR HOMOLOGY
Authors: FAUSER DANIEL , LÖH CLARA 
Published: June 2018

AbstractFunctorial semi-norms on singular homology give refined ‘size’ information on singular homology classes. A fundamental example is the ℓ1-semi-norm. We show that there exist finite functorial semi-norms on singular homology that are exotic in the sense that they arenotcarried by the ℓ1-semi-norm.
HOMOTOPY TYPES OF GAUGE GROUPS OVER NON-SIMPLYCONNECTED CLOSED 4-MANIFOLDS
Authors: SO TSELEUNG 
Published: June 2018

AbstractLet G be a simple, simply connected, compact Lie group, and let M be an orientable, smooth, connected, closed 4-manifold. In this paper, we calculate the homotopy type of the suspension of M and the homotopy types of the gauge groups of principal G-bundles over M when π1(M) is (1) ℤ*m, (2) ℤ/prℤ, or (3) ℤ*m*(*nj=1ℤ/prjjℤ), where p and the pj's are odd primes.
Strongly driven surface-global kinetic ballooning modes in general toroidal geometry
Authors: Zocco A. , Aleynikova K. , Xanthopoulos P. 
Published: June 2018

Kinetic ballooning modes in magnetically confined toroidal plasmas are investigated putting emphasis on specific stellarator features. In particular, we propose a Mercier criterion which is purposely designed to allow for direct comparison with local flux-tube gyrokinetics simulations. We investigate the influence on the marginal frequency of the mode of a magnetic curvature which is inhomogeneous on the magnetic flux surface due to the fieldline-label dependence. This is a typical (surface) global effect present in non-axisymmetry. Finally, we propose an artificial equilibrium model that explicitly retains the fieldline-label dependence in the magnetic drift, and analyse the stability of the system by introducing a representation of the perturbations similar to the flux-bundle model of Sugamaet al. (Plasma Fusion Res., vol. 7, 2012, 2403094). The coupling of flux bundles is shown to have a stabilising effect on the most unstable local flux-tube mode.