bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of branded rugby headguards on their effectiveness in reducing impact on the head
Authors: Frizzell Erin R A , Arnold Graham P , Wang Weijie , Abboud Rami J , Drew Tim S 
Published: October 2018

AimTo compare the available brands of rugby headguards and evaluate their impact attenuation properties at various locations on the cranium, with regard to concussion prevention.MethodsSeven different branded headguards were fitted onto a rigid headform and drop-tested in three different positions. An accelerometer measured the linear acceleration the headform experienced on impact with the ground. Each test involved dropping the headform from a height that generated 103.8 g on average when bare, which is the closest acceleration to the upper limit of the concussion threshold of 100 g. A mean peak acceleration for each drop position was calculated and compared with the bare baseline measurement.ResultsEach headguard demonstrated a significant decrease in the mean peak acceleration from the baseline value (all p≤0.01). Overall the Canterbury Ventilator was the most effective headguard, decreasing the impact force on average by 47%. The least effective was the XBlades Elite headguard, averaging a force reduction of 27%. In five of the seven headguards, the right side of the headwear was the most effective at reducing impact force.ConclusionOverall, the results indicate that it would be beneficial to wear a headguard during rugby in order to reduce the impact forces involved in head collisions. There was also a clear difference in performance between the tested brands, establishing the Canterbury headguard as the most effective. However, only one model of headguard from each brand was tested, so further research evaluating all other models should be considered.
Effectiveness of the 2014 European Society of Cardiology guideline on sudden cardiac death in hypertrophic cardiomyopathy: a systematic review and meta-analysis
Authors: O’Mahony Constantinos , Akhtar Mohammed Majid , Anastasiou Zacharias , Guttmann Oliver P , Vriesendorp Pieter A , Michels Michelle , Magrì Damiano , Autore Camillo , Fernández Adrián , Ochoa Juan Pablo , Leong Kevin M W , Varnava Amanda M , Monserrat Lorenzo , Anastasakis Aristides , Garcia-Pavia Pablo , Rapezzi Claudio , Biagini Elena , Gimeno Juan Ramon , Limongelli Giuseppe , Omar Rumana Z , Elliott Perry M 
Published: October 2018

ObjectiveIn 2014, the European Society of Cardiology (ESC) recommended the use of a novel risk prediction model (HCM Risk-SCD) to guide use of implantable cardioverter defibrillators (ICD) for the primary prevention of sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM). We sought to determine the performance of HCM Risk-SCD by conducting a systematic review and meta-analysis of articles reporting on the prevalence of SCD within 5 years of evaluation in low, intermediate and high-risk patients as defined by the 2014 guidelines (predicted risk <4%, 4%–<6% and ≥6%, respectively).MethodsThe protocol was registered with PROSPERO (registration number: CRD42017064203). MEDLINE and manual searches for papers published from October 2014 to December 2017 were performed. Longitudinal, observational cohorts of unselected adult patients, without history of cardiac arrest were considered. The original HCM Risk-SCD development study was included a priori. Data were pooled using a random effects model.ResultsSix (0.9%) out of 653 independent publications identified by the initial search were included. The calculated 5-year risk of SCD was reported in 7291 individuals (70% low, 15% intermediate; 15% high risk) with 184 (2.5%) SCD endpoints within 5 years of baseline evaluation. Most SCD endpoints (68%) occurred in patients with an estimated 5-year risk of ≥4% who formed 30% of the total study cohort. Using the random effects method, the pooled prevalence of SCD endpoints was 1.01% (95% CI 0.52 to 1.61) in low-risk patients, 2.43% (95% CI 1.23 to 3.92) in intermediate and 8.4% (95% CI 6.68 to 10.25) in high-risk patients.ConclusionsThis meta-analysis demonstrates that HCM Risk-SCD provides accurate risk estimations that can be used to guide ICD therapy in accordance with the 2014 ESC guidelines.Registration numberPROSPERO CRD42017064203;Pre-results.
Comparative analyses of responsiveness between the Rheumatoid Arthritis Impact of Disease score, other patient-reported outcomes and disease activity measures: secondary analyses from the ARCTIC study
Authors: Holten Karen , Sexton Joseph , Kvien Tore K , Aga Anna-Birgitte , Haavardsholm Espen A 
Published: October 2018

ObjectiveTo evaluate the responsiveness of the Rheumatoid Arthritis Impact of Disease (RAID) score compared with other patient-reported outcome measures (PROMs), inflammatory markers and clinical disease activity measures in patients with early rheumatoid arthritis (RA).MethodsDisease-modifying antirheumatic drug–naïve patients with RA with short disease duration were included in the treat-to-target ARCTIC trial and followed for 24 months. The responsiveness of the RAID score was evaluated using standardised response mean (SRM) and relative efficiency (RE) with respect to tender joints by Ritchie Articular Index (RAI). SRMs and REs were also calculated for other PROMs, inflammatory markers and clinical outcome measures. An SRM with value above 0.80 was considered high.Results230 patients with RA were included. The mean±SD symptom duration was 7.1±5.4 months and the baseline mean±SD  RAID score was 4.49±2.14. At 3 months of follow-up, the mean±SD change score for RAID was −2.25±1.98  and the SRM (95%  CI) −1.13 (−1.33 to −0.96). The RAID score showed high responsiveness both at 3 and 6 months (SRM≥0.80) and was more sensitive in detecting change than the reference, tender joints assessed by RAI.ConclusionsThe RAID score proved to be highly responsive to change in patients with RA with short disease duration who followed a treat-to-target strategy. The RAID score was more efficient in detecting change than the reference (RAI) as well as most other PROMs.
Effect of mandibular advancement therapy on inflammatory and metabolic biomarkers in patients with severe obstructive sleep apnoea: a randomised controlled trial
Authors: Recoquillon Sylvain , Pépin Jean-Louis , Vielle Bruno , Andriantsitohaina Ramaroson , Bironneau Vanessa , Chouet-Girard Frédérique , Fleury Bernard , Goupil François , Launois Sandrine , Martinez M Carmen , Meslier Nicole , Nguyen Xuan-Lan , Paris Audrey , Priou Pascaline , Tamisier Renaud , Trzepizur Wojciech , Gagnadoux Frédéric 
Published: October 2018

Systemic inflammation and metabolic disorders are among the mechanisms linking obstructive sleep apnoea (OSA) and cardiovascular disease (CVD). In 109 patients with severe OSA and no overt CVD, biomarkers of inflammation (C reactive protein, interleukin-6, tumour necrosis factor-α and its receptors, adiponectin, leptin and P-selectin), glucose and lipid metabolism, and N-terminal pro-brain natriuretic peptide, were measured before and after 2 months of treatment with a mandibular advancement device (MAD) (n=55) or a sham device (n=54). MAD reduced the Apnoea–Hypopnoea Index (p<0.001) but had no effect on circulating biomarkers compared with the sham device, despite high treatment adherence (6.6 hour/night).Trial registration numberNCT01426607.
Homological dimensions of skew group algebras
Authors: Xiang Yueming , Ouyang Lunqun 
Published: October 2018

Let [Formula: see text] be a finite dimensional algebra over a field [Formula: see text] and [Formula: see text] a subgroup of a finite group [Formula: see text]. In this paper, we consider the Gorenstein global dimensions and representation dimensions of the skew group algebras [Formula: see text] and [Formula: see text]. Under the assumption that [Formula: see text] is a separable extension over [Formula: see text], we show that [Formula: see text] and [Formula: see text] share the same Gorenstein global dimensions and representation dimensions. As an application, we give an affirmative answer for a conjecture raised in [Adjoint functors and representation dimensions, Acta Math. Sinica 22(2) (2006) 625–640]. Several known results are then obtained as corollaries.
A Multicenter Phase II Study of AMG 337 in Patients with MET-Amplified Gastric/Gastroesophageal Junction/Esophageal Adenocarcinoma and Other MET-Amplified Solid Tumors
Authors: Van Cutsem Eric , Karaszewska Boguslawa , Kang Yoon-Koo , Chung Hyun Cheol , Shankaran Veena , Siena Salvatore , Go Ning F. , Yang Hui , Schupp Marco , Cunningham David 
Published: October 2018

Abstract

Purpose:
MET gene amplification is associated with poor prognosis in gastric/gastroesophageal junction/esophageal (G/GEJ/E) cancers. We determined antitumor activity, safety, and pharmacokinetics of the small-molecule MET inhibitor AMG 337 in MET-amplified G/GEJ/E adenocarcinoma or other solid tumors.
Patients and Methods: In this phase II, single-arm study, adults with MET-amplified G/GEJ/E adenocarcinoma (cohort 1) or other MET-amplified solid tumors (cohort 2) received AMG 337 300 mg/day orally in 28-day cycles. The primary endpoint was objective response rate (ORR; cohort 1). Secondary endpoints included ORR (cohort 2), progression-free survival (PFS), overall survival (OS), and safety.

Results:
Of 2101 patients screened for MET amplification, 132 were MET-amplified and 60 were enrolled: 45 in cohort 1, and 15 in cohort 2. Fifty-six patients (97%) had metastatic disease; 57 had prior lines of therapy (1 prior line, 29%; ≥2 prior lines, 69%). A protocol-permitted review showed efficacy that was lower-than-expected based on preliminary data from a first-in-human study, and enrollment was stopped. Fifty-eight patients received ≥1 AMG 337 dose. ORR in cohort 1 was 18% (8 partial responses). No responses were observed in cohort 2. Of 54 evaluable patients, median (95% CI) PFS and OS were 3.4 (2.2–5.0) and 7.9 (4.8–10.9) months, respectively. The most frequent adverse events (AEs) were headache (60%), nausea (38%), vomiting (38%), and abdominal pain, decreased appetite, and peripheral edema (33% each); 71% had grade ≥3 AEs and 59% had serious AEs.

Conclusions:
AMG 337 showed antitumor activity in MET-amplified G/GEJ/E adenocarcinoma but not in MET-amplified non–small-cell lung cancer.
See related commentary by Ma, p. 2375
Amorphophallus longiconnectivus and A. margaritifer: additional aroids from Maharashtra with notes on the floral variations
Authors: Gholave Avinash R. , Govekar Ravikiran S. , Kahalkar Vasanta I. , Sardesai Milind M. , Yadav Shrirang R. 
Published: October 2018

Amorphophallus longiconnectivus Bogner and A. margaritifer (Roxb.) Kunth are reported for the state of Maharashtra. In addition to this the notes on variations in spadices of the species has also been provided.
A new report on the clasper movements of a captive Sand Tiger Shark Carcharias taurus (Lamniformes: Odontaspididae) and a possible reason for the behaviour
Authors: Colbachini Helen , Gutierrez Rafael Caprioli , Pizzutto Cristiane Schilbach , Gadig Otto Bismarck Fazzano 
Published: October 2018

Elasmobranchs present four clasper movements, which can be seen in different contexts from mating to no obvious reason. Three movements have been reported in Carcharias taurus and here the first occurrence of clasper flaring in this species is described. Clasper flaring was observed while other species were in a reproductive state and their aggressive behaviour towards the subject of this study was also observed.
First record of the endangered Arabian Tahr Arabitragus jayakari (Thomas, 1894) in the Hatta Mountain Conservation Area, Dubai, United Arab Emirates
Authors: Aguhob Jeruel Cabadonga , Shah Junaid N. , Elhassan Esmat Elfaki Mohammed , Muhery Aisha Almurr Al , Mohamed Mohamed Mustafa Eltayeb , Al Omairi Juma Abdulla Saeed Mohammad , Albedwawi Hamad Hashim Mohammed Khalaf , Al Bedwawi Obaid Mohammed Salem Mohammed , Alsharif Hassan Zain , Ali Haji Afra Mahmood Mohammad 
Published: October 2018

The Arabian Tahr Arabitragus jayakari is endemic to the Hajar Mountains of Oman and the United Arab Emirates in the southeast of the Arabian Peninsula and is categorized as Endangered on the IUCN Red List of Threatened Species. Lack of scientific research from areas of its occurrence has been a challenge in determining its basic ecological aspects such as current distribution range, population status, and abundance. In the present study, we report a new distribution record for the Arabian Tahr from the Hatta Mountain Conservation Area in the Dubai Emirate through camera trap images. A total of 442 images (44 events) were obtained using three camera traps on 564 trap nights between March and December 2016. About 90% of the Arabian Tahr captures were recorded between 1100 and 1600 hr, indicating diurnal activity. This new occurrence record of the Arabian Tahr from this area is considered of high significance as it will drive in more studies and incentives towards the conservation and management of the species and the area as a whole.
The terrestrial life of sea kraits: insights from a long-term study on two Laticauda species (Reptilia: Squamata: Elapidae) in the Andaman Islands, India
Authors: Tyabji Zoya , Mohanty Nitya Prakash , Young Erina , Khan Tasneem 
Published: October 2018

Sea kraits forage in water and return to land to digest their prey, mate, slough, and lay their eggs. The temporal terrestrial patterns in encounter rate and behaviour of two species of sea kraits Laticauda colubrina and L. laticaudata were studied over four years at the New Wandoor beach in the southern Andaman Islands. The encounter rate of L. colubrina was found to be 20 times higher than L. laticaudata, and sea kraits were observed to prefer the natural refuge that the microhabitat of uprooted trees provide. Additionally, nesting observations are presented that emphasize the need to promote the conservation of these crucial terrestrial habitats.
Consequence and Formality in the Logic of Walter Burley
Authors: Archambault Jacob 
Published: October 2018

Abstract
With William of Ockham and John Buridan, Walter Burley is often listed as one of the most significant logicians of the medieval period. Nevertheless, Burley’s contributions to medieval logic have received notably less attention than those of either Ockham or Buridan. To help rectify this situation, the author here provides a comprehensive examination of Burley’s account of consequences, first recounting Burley’s enumeration, organization, and division of consequences, with particular attention to the shift from natural and accidental to formal and material consequence, and then locating Burley’s contribution to the theory of consequences in the context of fourteenth-century work on the subject, detailing its relation to the earliest treatises on consequences, then to Ockham and Buridan.
The Roots of the Notion of Containment in Theories of Consequence
Authors: Bosman Bianca 
Published: October 2018

Abstract
In medieval theories of consequence, we encounter several criteria of validity. One of these is known as the containment criterion: a consequence is valid when the consequent is contained or understood in the antecedent. The containment criterion was formulated most frequently in the thirteenth and fourteenth centuries, but it can be found in earlier writings as well. In The Tradition of the Topics in the Middle Ages, N.J. Green-Pedersen claimed that this criterion originated with Boethius. In this article, the author shows that a notion of containment is indeed present in Boethius, but is not used to define or describe the relation between antecedent and consequent, i.e., the relation of consequence, as Green-Pedersen asserted. The author then offers two interpretations of the notion of containment that are present in Boethius – a metaphysical and a semantic interpretation – and shows how these relate to the containment criterion.
A new and two known species of Hatschekia Poche, 1902 (Copepoda, Siphonostomatoida, Hatschekiidae) parasitic on Japanese fishes
Authors: Izawa Kunihiko 
Published: October 2018

Abstract
Hatschekia laeopsi sp. nov., H. branchiostegi Yamaguti, 1939 and H. pagrosomi Yamaguti, 1939 are (re-)described based on specimens collected from the branchial lamellae of three Japanese fishes, Laeops kitaharae (Smith & Pope, 1906) (Pleuronectidae), Branchiostegus japonicus (Houttuyn, 1782) (Malacanthidae), and Dentex tumifrons (Temminck & Schlegel, 1843) (Sparidae), respectively. The free-living stages of H. branchiostegi are described for the species for the first time.
Investigations on unexplored brachyurans (Decapoda), Charybdis hoplites (Wood-Mason, 1877) and Charybdis smithii MacLeay, 1838, from trawl discards of the Southeast Arabian Sea ecosystem
Authors: Dineshbabu A. P. , Thomas Sujitha , Maheswarudu G. 
Published: October 2018

Abstract
The effectiveness of GIS-based resource mapping to strengthen the database for Ecosystem-Based Fisheries Management (EBFM), was tested in an attempt at resolving the existing gap in the data on non-commercial resources. In this paper we describe the result of that try by giving an example of one of the most important influential species in the benthic ecosystem of the Southeast Arabian Sea (SEAS). An estimated 2803 t of Charybdis hoplites, a relatively little known species from the coast, are yearly caught and discarded by trawlers operating from the Mangalore fisheries harbour. A GIS-aided study on distribution and abundance estimated, that the average biomass of the species is 322.7 t, at any time in the area covered. This study brings out the fact that a number of non-commercial biota are serving as non-detectable factors in sustaining productivity. The identification of their role and the quantification of their biomass thus constitute important data for an effective implementation of EBFM.
Improvement of Soil Respiration Parameterization in a Dynamic Global Vegetation Model and Its Impact on the Simulation of Terrestrial Carbon Fluxes
Authors: Kim Dongmin , Lee Myong-In , Seo Eunkyo 
Published: October 2018

Abstract
The Q10 value represents the soil respiration sensitivity to temperature often used for the parameterization of the soil decomposition process has been assumed to be a constant in conventional numerical models, whereas it exhibits significant spatial and temporal variation in the observations. This study develops a new parameterization method for determining Q10 by considering the soil respiration dependence on soil temperature and moisture obtained by multiple regression for each vegetation type. This study further investigates the impacts of the new parameterization on the global terrestrial carbon flux. Our results show that a nonuniform spatial distribution of Q10 tends to better represent the dependence of the soil respiration process on heterogeneous surface vegetation type compared with the control simulation using a uniform Q10. Moreover, it tends to improve the simulation of the relationship between soil respiration and soil temperature and moisture, particularly over cold and dry regions. The modification has an impact on the soil respiration and carbon decomposition process, which changes gross primary production (GPP) through controlling nutrient assimilation from soil to vegetation. It leads to a realistic spatial distribution of GPP, particularly over high latitudes where the original model has a significant underestimation bias. Improvement in the spatial distribution of GPP leads to a substantial reduction of global mean GPP bias compared with the in situ observation-based reference data. The results highlight that the enhanced sensitivity of soil respiration to the subsurface soil temperature and moisture introduced by the nonuniform spatial distribution of Q10 has contributed to improving the simulation of the terrestrial carbon fluxes and the global carbon cycle.
Platelet-rich plasma to rescue an ulcerated orbital dermal fat graft
Authors: Chaparro Tapias Tania Andrea , Díaz Díaz Alberto Luis , Secondi Roberto , Coy Villamil Helena , Sánchez España Juan Carlos 
Published: October 2018

Introduction: Central graft ulceration is a rare complication of an orbital dermal fat graft caused by diminished blood supply to the implant. This study reports on the efficacy and safety of the use of a single subconjunctival injection of autologous platelet-rich plasma to rescue an ulcerated orbital dermal fat graft. Methods: Three patients, who had undergone autologous dermal fat graft to treat their anophthalmic socket, were given a 2-mL subconjunctival platelet-rich plasma injection in the exposed graft margins. Demographic and clinical features, treatment protocol, clinical course, complications and follow-up time are reported. In the preoperative examination, all the patients presented a primary epithelial defect of the dermal fat graft. Results: There were no major complications such as necrosis or infection. One patient presented a small conjunctival granuloma at 1-month follow up. Mean postoperative follow-up duration was 13 (range: 10–16) months. By 1 month, the chronic epithelial defect had resolved with the graft integrated within the orbital tissues in all cases. All patients were referred for artificial prosthesis placement. Conclusion: Although further work is needed, our findings suggest that a single subconjunctival platelet-rich plasma injection could be an effective, safe and economic alternative to surgery to rescue an ulcerated orbital dermal fat graft.
Right bundle branch block in patients with suspected myocardial infarction
Authors: Neumann Johannes Tobias , Sörensen Nils Arne , Rübsamen Nicole , Ojeda Francisco , Schäfer Sarina , Keller Till , Blankenberg Stefan , Clemmensen Peter , Westermann Dirk 
Published: October 2018

Aims: The new European Society of Cardiology guideline for ST-segment elevation myocardial infarction recommends that left and right bundle branch block should be considered equal for recommending urgent angiography in patients with suspected myocardial infarction. We aimed to evaluate this novel recommendation in two prospective studies of patients with suspected myocardial infarction. Methods and results: We included 4067 patients presenting to the emergency department with suspected myocardial infarction. All patients had an ECG recorded immediately upon admission. Patients were classified as having right bundle branch block (RBBB), left bundle branch block (LBBB), bifascicular block (BFB) or no bundle branch block. All patients were followed for up to two years to assess mortality. In the overall population 125 (3.1%) patients had RBBB, 281 (6.9%) LBBB and 60 (1.5%) BFB. The final diagnosis of myocardial infarction was adjudicated in 20.8% (RBBB), 28.5% (LBBB), 23.3% (BFB) and 21.6% (no complete block) of patients. The mortality rate after one year was 10.7% (RBBB), 7% (LBBB), 17.5% (BFB) and 3.2% (no complete block). The adjusted hazard ratios were 1.29 (95% confidence interval (CI) 0.71–2.34; P=0.40) for RBBB, 1.71 (95% CI 1.17–2.50; P=0.006) for LBBB and 2.27 (95% CI 1.28–4.05; P=0.005) for BFB. Conclusion: Our results support the new European Society of Cardiology ST-segment elevation myocardial infarction guideline describing RBBB as a high risk for mortality in patients with suspected myocardial infarction. However, the data challenge the concept of RBBB as a trigger of acute angiography because the likelihood of myocardial infarction in a chest pain unit setting is equally frequent in patients without bundle branch block.