bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intangible Matters
Authors: Figal Günter 
Published: October 2018

Abstract
This paper is on matter and on art. Based on the assumption that the everyday attitude toward the world is a kind of materialistic realism and that philosophers, from the beginning of philosophy on, have objected to the plausibility of epistemological reliance on matter, I make attempts to investigate what matter is. I suggest doing this in reference to art. In particular I discuss works of art representing kinds of matter so extraordinary that their material character even could be doubted: light and sound. An installation by James Turrell and a piece of music composed by Morton Feldman, Rothko Chapel, function as paradigms to demonstrate the material character of light and sound and also the affinity of matter to space. Having qualities, matter proves to be different from space; being amorphous, however, matter as such has no distinct appearance, but, like space, enables appearance.
On Music and Memory through Μνήµη and Ἀνάµνησις
Authors: Wiskus Jessica 
Published: October 2018

Abstract
Memory plays an integral role in music listening and music performance. But what specific memory structures do we employ when we engage with music? Taking Aristotle’s De memoria et reminiscentia as principle guide, I aim to press upon a matter of central interest to the phenomenologist of music, focusing on the relation between memory proper [µνήµη] and recollection [ἀνάµνησις]. Drawing upon Physics IV and De anima III, I clarify a two-fold temporal structure—a structure comprised of sensation and flowing continuity—at work in the experience of remembering. Finally, I claim that music, through the ordered expression of its successive sensations, pertains directly to ἀνάµνησις but supports access to µνήµη, as well.
Δύναµις and Dasein, Ἐνέργεια and Ereignis
Authors: Gonzalez Francisco J. 
Published: October 2018

Abstract
The “destructive” appropriation of the Aristotelian concepts of δύναµις and ἐνέργεια played a central role in Martin Heidegger’s own reflection on the meaning of being. While this has been generally known for some time, it is only now that we can understand the full scope, complexity and evolving character of this appropriation. One reason is the fairly recent publication (in 2012, Gesamtausgabe 83) of notes and protocols for seminars Heidegger led on Aristotle as late as the 1940s and 1950s. Another is the existence of student transcripts in the Special Collections Department of Stanford University for a number of unpublished seminars on Aristotle that Heidegger led during the 1920s. Considering all of this material enables us to see both the significance of Heidegger’s interpretation of the δύναµις/ἐνέργιεα pair as well as how this interpretation evolved along with his own “Kehre”: from a “pandynamic” conception of being to being as “Ereignis.”
EarthCARE’s Broadband Radiometer: Uncertainties Associated with Cloudy Atmospheres
Authors: Tornow F. , Barker H. W. , Blázquez Velázquez , Domenech C. , Fischer J. 
Published: October 2018

AbstractThe Earth Clouds, Aerosol and Radiation Explorer (EarthCARE) satellite’s Broadband Radiometer (BBR) consists of three telescopes and a rotating chopper drum (CD). Together they yield alternating measurements of total wave (TW; 0.25 to >50 μm) and shortwave (SW; 0.25–4 μm) radiances with point spread functions that translate to 0.6-km-diameter pixels. The mission requires that SW and TW radiances be averaged over 100-km2 domains. Correspondingly, the average longwave (LW) radiances are the differences between TW and SW averages. It is shown that impacts on domain-average nadir radiances resulting from alternating samples of TW and SW signals for realistic cloudy atmospheres are sensitive to the variance of cloudy-sky radiances, CD rotation rate, and along-track length of averaging domains. Over domains measuring 5 × 21 km2 and at a 50% rotation rate, uncertainties reached up to 3.2 and 4.1 W m−2 sr−1 for SW and TW radiances, respectively. The BBR’s design allows for in-flight alteration of the CD rate. An approximate method is provided for estimating SW and LW uncertainties resulting from the CD rate. While the nominal rotation rate meets EarthCARE’s mission requirements, reducing below 75% of that rate will lead to uncertainties for domain-average LW radiances that will often exceed mission requirements. This could be mitigated by increasing the size of averaging domains but that would compromise the BBR’s role in EarthCARE’s radiative closure assessment program. Uncertainties for off-nadir radiances are largely free of impacts arising from changes to the CD rotation rate.
An Analog Technique to Improve Storm Wind Speed Prediction Using a Dual NWP Model Approach
Authors: Yang Jaemo , Astitha Marina , Delle Monache Luca , Alessandrini Stefano 
Published: October 2018

Abstract
This study presents a new implementation of the analog ensemble method (AnEn) to improve the prediction of wind speed for 146 storms that have impacted the northeast United States in the period 2005–16. The AnEn approach builds an ensemble by using a set of past observations that correspond to the best analogs of numerical weather prediction (NWP). Unlike previous studies, dual-predictor combinations are used to generate AnEn members, which include wind speed, wind direction, and 2-m temperature, simulated by two state-of-the-science atmospheric models [the Weather Research and Forecasting (WRF) Model and the Regional Atmospheric Modeling System–Integrated Community Limited Area Modeling System (RAMS–ICLAMS)]. Bias correction is also applied to each analog to gain additional benefits in predicting wind speed. Both AnEn and the bias-corrected analog ensemble (BCAnEn) are tested with a weighting strategy, which optimizes the predictor combination with root-mean-square error (RMSE) minimization. A leave-one-out cross validation is implemented, that is, each storm is predicted using the remaining 145 as the training dataset, with modeled and observed values over 80 stations in the northeast United States. The results show improvements of 9%–42% and 1%–29% with respect to original WRF and ICLAMS simulations, as measured by the RMSE of individual storms. Moreover, for two high-impact tropical storms (Irene and Sandy), BCAnEn significantly reduces the error of raw prediction (average RMSE reduction of 22% for Irene and 26% for Sandy). The AnEn and BCAnEn techniques demonstrate their potential to combine different NWP models to improve storm wind speed prediction, compared to the use of a single NWP.
The Political Dynamic of Redistribution in Unequal Democracies: The Center-Left Governments of Chile and Uruguay in Comparative Perspective
Authors: Antía Florencia 
Published: October 2018

The redistributive reforms carried out by center-left governments in Chile and Uruguay in the 2000s affected the core interests of economic elites. Efforts to increase taxes on high-income sectors and reform the institutions that regulate the capital-labor relationship produced different results in the two countries. While Uruguay adopted significant reforms, reforms in Chile were marginal in 2000–2010 and moderate in 2014–2016. Their different trajectories are related to different configurations of the distribution of power resources between the elites and the social organizations that represent the interests of low-income sectors. Las reformas redistributivas llevadas a cabo por los gobiernos de centro-izquierda en Chile y Uruguay en la década de 2000 afectaron los intereses centrales de las élites económicas. Los esfuerzos para aumentar los impuestos a los sectores de altos ingresos y reformar las instituciones que regulan la relación capital-trabajo produjeron resultados diferentes en los dos países. Mientras que Uruguay adoptó reformas significativas, las reformas en Chile fueron marginales en 2000–2010 y moderadas en 2014–2016. Sus diferentes trayectorias están relacionadas con diferentes configuraciones de la distribución de recursos de poder entre las élites y las organizaciones sociales que representan los intereses de los sectores de bajos ingresos.
Exosomes Derived from IDO1-Overexpressing Rat Bone Marrow Mesenchymal Stem Cells Promote Immunotolerance of Cardiac Allografts
Authors: He Ji-Gang , Xie Qiao-Li , Li Bei-Bei , Zhou Liang , Yan Dan 
Published: October 2018

Background: The immunosuppressive activity of mesenchymal stem cells (MSCs) has been exploited to induce tolerance after organ transplantation. The indoleamine 2,3-dioxygenase (IDO) may have beneficial effects in the immunoregulatory properties of MSCs. It was recently revealed that exosomes derived from MSCs play important roles in mediating the biological functions of MSCs. This study aimed to explore the roles of exosomes derived from MSCs in the induction of immune tolerance. Methods: Dendritic cells (DCs) and T-cells were cultured with exosomes derived from rat bone marrow MSCs (BMSCs) overexpressing IDO1 or controls. For the in-vivo study, rats received heart transplants and were treated with exosomes from IDO-BMSCs and heart function was evaluated. Flow cytometry was used to detect expression of cell surface markers. Cytokine levels were detected in culture supernatants or serum samples. Protein and microRNA expressions in exosomes were investigated by chips. Results: Exosomes from IDO-BMSCs cultured with DCs and T-cells (1) downregulated CD40, CD86, CD80, MHC-II, CD45RA, CD45RA+CD45RB, OX62, and upregulated CD274 expression, (2) increased the number of regulatory T-cells (Tregs) and decreased the number of CD8+ T-cells, and (3) decreased the levels of pro-inflammatory cytokines, but increased the levels of anti-inflammatory cytokines compared with the other groups. Transplanted rats, which were injected with exosomes from IDO-BMSCs, had reduced allograft-targeting immune responses and improved cardiac allograft function. Exosomes secreted by IDO-BMSCs exhibited significant upregulations of the immunoregulatory protein FHL-1, miR-540-3p, and a downregulation of miR-338-5p. Conclusion: Exosomes derived from IDO-BMSCs can be used to promote immunotolerance and prolong the survival of cardiac allografts.
Comparison of Sino-Nasal Outcome Test 22 Symptom Scores in Rhinogenic and Odontogenic Sinusitis
Authors: Simuntis Regimantas , Vaitkus Justinas , Kubilius Ričardas , Padervinskis Evaldas , Tušas Paulius , Leketas Marijus , Šiupšinskienė Nora , Vaitkus Saulius 
Published: October 2018

Background Odontogenic maxillary sinusitis (OMS) and rhinogenic sinusitis (RS) are the main types of chronic rhinosinusitis (CRS) and have a significant impact on health-related quality of life (HRQL), but the difference in HRQL and symptom presentation between them has not been specifically evaluated to date. Obejctive: Our aim was to compare patterns of symptoms and HRQL disease-specific domains in patients affected with these 2 types of CRS. Methods A group of 201 patients with CRS (99 with rhinogenic and 102 with odontogenic origin) completed the Sino-Nasal Outcome Test 22 (SNOT-22) questionnaire before treatment. Data sets were analyzed by using principal component analysis (PCA) to identify a set of symptom components together with the items excluded from PCA, which were then analyzed for differences between patients with OMS and RS. Results PCA of SNOT-22 items identified 5 components: “rhinologic,” “extranasal rhinologic,” “ear/facial,” “sleep and functional disturbance,” and “emotional disturbance.” Sneezing was excluded from PCA and treated as separate outcome variable and was significantly worse in RS patients. Patients with OMS scored significantly higher scores with regard to emotional disturbance, while RS patients scored significantly worse in sleep and functional disturbance. The extra symptom “malodor” was the most different symptom and was significantly worse in OMS patients. The total SNOT-22 score was not significantly different between the groups. Conclusion With controlling of covariates that may influence the severity of the disease, this study showed some significant differences in symptom patterns and HRQL impairment between patients with OMS and RS. Malodor is the most characteristic feature of OMS. Therefore, OMS should always be suspected in patients complaining of bad breath.
Imaging findings in spinal sarcoidosis: a report of 18 cases and review of the current literature
Authors: Soni Neetu , Bathla Girish , Pillenahalli Maheshwarappa Ravishankar 
Published: October 2018

Purpose Spinal sarcoidosis, referring to involvement of the spine in sarcoidosis, is relatively rare and may mimic other neurological disease affecting the spine. The authors present a clinic radiological review of 18 spinal sarcoidosis patients who presented to a tertiary hospital, with emphasis on initial imaging and radiological response to treatment. Materials and methods We retrospectively reviewed our departmental imaging archives over a 15-year period and found 49 cases of neurosarcoidosis out of which 18 patients had spinal magnetic resonance imaging. Results Approximately 72% (13/18) of the neurosarcoidosis patients showed some form of spinal involvement. The clinical, epidemiological and imaging data were reviewed for these 13 patients at presentation and follow-up. The findings on magnetic resonance imaging included leptomeningeal enhancement (61%), pachymeningeal (23%), intramedullary enhancing lesions (38%) and bony involvement (15%). The cervical segment was most frequently involved followed by the thoracic segment. Involvement was often long segment (4.2 spinal segments) with proclivity for the dorsal cord. Mean follow-up was 23.2 months. A complete or near-complete radiological response occurred in 66% while partial response was seen in 25% patients. Four patients had isolated central nervous system involvement including one with isolated spinal cord involvement. On diffusion-weighted imaging, the apparent diffusion coefficient of intramedullary lesions was increased compared to normal-appearing cord on baseline and subsequent follow-up scans. Conclusions Spinal sarcoidosis was previously considered uncommon but is being increasingly recognized with widespread use of magnetic resonance imaging. Proclivity for dorsal surface involvement is characteristic, although not necessarily pathognomonic. Also, quantitative diffusion studies may serve as a biomarker for the disease activity and parenchymal injury.
Vibrational spectroscopic analysis of hydroxyapatite in HYP mice and individuals with X-linked hypophosphatemia
Authors: Amenta Eva , King Helen E. , Petermann Holger , Uskoković Vuk , Tommasini Steven M. , Macica Carolyn M. 
Published: October 2018

Background: X-linked hypophosphatemia (XLH) is the most common form of familial phosphate-wasting disorders, due to an inactivating mutation in the phosphate-regulating neutral endopeptidase, X-linked gene. Persistent osteomalacia, enthesophytes, osteophytes, degenerative arthritis and dental abscesses/periodontal disease dominate the adult disorder. However, the impact of insufficient phosphate on hydroxyapatite composition, the major inorganic component of bone and teeth, is unknown in individuals with XLH. Methods: Using Raman spectroscopy, the carbonate (CO32−) to phosphate (PO43−) ion ratio was measured in HYP and wild-type mice and in primary and permanent teeth from XLH individuals and unaffected controls. Results: There was a significant difference in carbonate ion substitution between the HYP and wild-type femoral cortical bone (0.36 ± 0.08 versus 0.24 ± 0.04; p < 0.001). Carbonate ion substitution levels were also higher in permanent XLH teeth compared with unaffected individuals (0.39 ± 0.12 versus 0.23 ± 0.04; p < 0.001), but not in primary teeth (0.29 ± 0.11 versus 0.26 ± 0.02; p = 0.29). Complementary Fourier transform infrared analyses demonstrated higher relative intensities of the four major vibrational bands originating from the carbonate anion in XLH teeth compared with unaffected controls. Conclusion: Ionic substitution within the crystal lattice is a common feature of hydroxyapatite and one that confers the physiological properties of bone that impact mechanical strength and the process of bone remodeling. Our data demonstrating anionic substitution in human dentin from individuals with XLH validate the use of dentin as a proxy for bone and to better understand the molecular adaptations that occur in the biochemical milieu of XLH.
Safety assessment of concurrent statin treatment and evaluation of drug interactions in China
Authors: Yan Ming-Ming , Wu Shu-Shan , Ying Yin-Qing , Lu Nan , Zhong Ming-Kang 
Published: October 2018

Objectives: Acute muscle injury and potentially fatal rhabdomyolysis may occur with the use of statins and certain enzyme inhibitors, but data on this topic from China are quite limited. This study aimed to measure the concomitant exposure of patients to different statins and their enzyme inhibitors or interacting medications in 76 hospitals in six Chinese cities. Methods: Prescription database was retrieved from Hospital Prescription Analysis Cooperation Project from January 2015 to December 2015, covering 76 tertiary facilities in six cities in China. Every evidence-based enzyme inhibitor was included, and labeled enzyme inhibitors and other relevant information were identified and obtained using the Drug Safety Update from the UK Medicines and Healthcare Products Regulatory Agency. The proportions of different statin types among all patients and those co-medicated with their inhibitors were examined. Results: A total of 296,765 patients exposed to statins were included in this study. 80% of patients (n = 144,863, 80.5%) were concomitantly prescribed a CYP3A4-metabolized statin with an interacting drug during the study period. Among those prescribed a non-CYP3A4-metabolized statin, 40.0% of patients were concomitantly given an interacting drug, and approximately 20% of patients were concomitantly given a labeled inhibitor, predominantly calcium channel blockers, other statins, and fibrates. Rates of co-prescription were higher in patients aged over 65 years and in patients taking high-dose statins. Conclusion: Statins were frequently co-prescribed with metabolic inhibitors in China, where drug safety strategy on highlighting warnings and contraindications of statins are still lacking. For high-dose statins patients who are over 65 years and co-administered with any metabolic inhibitors, prescribers and pharmacists should be more concerned in order to prevent adverse drug reactions.
Centre of pressure during quiet stance and dual-task one month after mild traumatic brain injury: In adolescents
Authors: Walters-Stewart Coren , Rochefort Coralie , Longtin Andre , Zemek Roger , Sveistrup Heidi 
Published: October 2018

Background Mild traumatic brain injury is a common neurological condition affecting adolescents in North America. In adults, symptoms related to balance are some of the most commonly reported. Methods The purpose of this study was to investigate the balance in adolescents with mild traumatic brain injury using linear and non-linear centre of pressure (COP) measures in quiet stance and during dual-task. Adolescents aged 13.00 to 17.99 years were tested once at one month following mild traumatic brain injury (n = 25), and healthy adolescents (n = 22) were tested once as controls in four conditions: standing with eyes open, standing with eyes closed, standing on a single leg and standing while performing a visual Stroop task. Results In general, compared to healthy adolescents, adolescents with mild traumatic brain injury demonstrated more variability ( p = 0.007, 95% CI (0.9, 5.4) and p = 0.049, 95% CI (0.009, 4.0), mediolateral and anteroposterior, respectively), showed more cumulative movement (path length, p = 0.016, 95% CI (1.3, 11.9)) and required greater speed of movement ( p = 0.012, 95% CI (0.99, 7.4) and p = 0.035, 95% CI (0.28, 7.5), mediolateral and anteroposterior, respectively) in maintaining balance, and in underlying temporal organization showed less local stability (mediolateral largest Lyapunov, p = 0.033, 95% CI (0.001, 0.027)), more short-term complexity anteroposteriorly ( p = 0.029, 95% CI (0.005, 0.099)) and less long-term complexity mediolaterally ( p = 0.001, 95% CI (0.015, 0.056)). Condition differences are additionally presented. Conclusions Findings suggest that, for adolescents with mild traumatic brain injury, when maintaining balance visual input is relied on differently, the effectiveness of control may be an issue during dual-task, and consequently, the challenge of dual-task may be on par with single leg stance.
Dentinal Microcrack Formation During Root Canal Treatment with Mtwo Instruments and MicroSeal Filling Technique
Authors: Carlesi Teocrito , Nigro Giuseppe , Giacomo Luigi Di , Plotino Gianluca , Malagnino Vito Antonio 
Published: October 2018

Objective: The purpose of this study was to evaluate dentinal microcrack formation during root canal treatment using Mtwo NiTi rotary instruments and MicroSeal filling technique. Materials and Methods: Forty-five single-rooted teeth were selected for the present study and divided into 3 different groups ( n = 15): Group 1, in which root canals were instrumented with Mtwo rotary files; Group 2, in which root canals were instrumented with Mtwo rotary files and filled using the MicroSeal technique; and Group 3, that acts as a control group in which no instrumentation nor obturation were performed. Then, roots were sectioned 3 mm, 6 mm, and 9 mm from the apex and the cut surface has been observed under a stereomicroscope to check for the presence or absence of dentinal microcracks. Number of dentinal microcracks was registered for each group at different levels and data were statistically analyzed using the Chi-square test with a level of significance set at P < .05. Results: No statistically significant differences were registered among groups ( P < .05). No microcracks were detected in Groups 1 and 3, while two dentinal microcracks were registered in Group 2. Conclusions: Mtwo rotary instruments and the MicroSeal root canal filling technique did not significantly induce dentinal microcrack formation.
Job dissatisfaction and migration: evidence from Tajikistan
Authors: Abdulloev Ilhom 
Published: October 2018

AbstractHaving a family member migrant reduces not only the labor force participation but also the job satisfaction of those left behind. Migrants’ relatives build their expectations on earnings from migration through received information on the wage distribution in the destination country either from the size of remittances or directly from migrants. If their expected earnings from migration greatly exceed their current wages in the source country, migrant relatives become more dissatisfied with their jobs. Using a simple economic model of job satisfaction and applying both parametric and semiparametric estimations to Tajikistan’s data, as well as with controlling for an endogeneity issue with the variable of interest, we estimate the significantly positive effect of the difference of the expected outside country earnings and current earnings of migrants’ relatives on their job dissatisfaction. A larger gap between what an individual could earn in the migration destination country and what she receives now at her current job in the source country makes that individual unhappier.