bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brassica Panache: A multi‐species graph pangenome representing presence absence variation across forty‐one Brassica genomes
Authors: MacNish Tessa R. , Al‐Mamun Hawlader A. , Bayer Philipp E. , McPhan Connor , Fernandez Cassandria G. Tay , Upadhyaya Shriprabha R. , Liu Shengyi , Batley Jacqueline , Parkin Isobel A. P. , Sharpe Andrew G. , Edwards David 
Published: December 2024

AbstractBrassicas are an economically important crop species that provide a source of healthy oil and vegetables. With the rising population and the impact of climate change on agriculture, there is an increasing need to improve agronomically important traits of crops such as Brassica. The genomes of plant species have significant sequence presence absence variation (PAV), which is a source of genetic variation that can be used for crop improvement, and this species variation can be captured through the construction of pangenomes. Graph pangenomes are a recent reference format that represent the genomic variation with a species or population as alternate paths in a sequence graph. Graph pangenomes contain information on alignment, PAV, and annotation. Here we present the first multi‐species graph pangenome for Brassica visualized with pangenome analyzer with chromosomal exploration (Panache).
Understanding resilience: Contributions of urban agriculture to the resilience of urban landscapes
Authors: Ghahremani Vahid , Noori Omid , Deihimfard Reza , Veisi Hadi 
Published: December 2024

AbstractUrban agriculture (UA) has been explored as a nature‐based solution to address metropolises' socioecological challenges. The current study strives to determine which dimensions and components of socioecological resilience are most affected by UA in urban ecosystems. Q‐methodology was applied to identify shared discourses between experts in UA and to provide insights into how experts perceive resilience in socioecological ecosystems. The data were gathered by completing the Q table (41 statements) and interviewing experts (29 participants) in agriculture, urban planning, environmental science, urban landscape, and urban practice. The results revealed seven distinct perspectives possessed by experts with eigenvalues of 11.23, 2.37, 1.94, 1.48, 1.39, 1.25, and 1.11 and explanatory variances of 0.387, 0.08, 0.067, 0.05, 0.04, 0.04, and 0.03, respectively. The perspectives included (1) promoting a happy and healthy life, (2) integrating land use, waste, and energy management, (3) ensuring food security and protection of production resources, (4) promoting social interaction and relaxation, (5) improving biodiversity and picture quality, (6) motivating creativity for community health, and (7) reducing the ecological footprint and cost and food insecurity. Each perspective entails a different understanding of the role of UA on socioecological resilience in metropolitan areas. The results contribute to the ongoing theoretical discussion regarding the nature of the current UA in metropolises, its development, and potential conventionalization. Overall, these findings suggest a role for UA in promoting resilience in metropolises to make them socially and ecologically better places for life.
Brain Predictability Toolbox
Authors: Hahn Sage , Allgaier Nicholas , Garavan Hugh 
Published: December 2024

AbstractThe Brain Predictability toolbox (BPt) is a Python-based library with a unified framework of machine learning (ML) tools designed to work with both tabulated data (e.g., brain-derived, psychiatric, behavioral, and physiological variables) and neuroimaging specific data (e.g., brain volumes and surfaces). The toolbox is designed primarily for ‘population’-based predictive neuroimaging; that is to say, machine learning performed across data from multiple participants rather than many data points from a single or small set of participants. The BPt package is suitable for investigating a wide range of neuroimaging-based ML questions. This chapter is a brief introduction to general principles of the toolbox, followed by a specific example of usage.
Studying the Connectome at a Large Scale
Authors: Boyle Rory , Weng Yihe 
Published: December 2024

AbstractThis chapter outlines a flexible connectome-based predictive modeling method that is optimised for large neuroimaging datasets via the use of parallel computing and by adding the capability to account for possible site- and scanner-related heterogeneity in multi-site neuroimaging datasets. We present the decision points that need to be made when conducting a connectome-based predictive modeling analysis and we provide full code to conduct an analysis on public data. To date, connectome-based predictive modeling has been applied to predict different cognitive and behavioral phenotypes with many studies reporting accurate predictions that generalized to external datasets.
Neuroimaging Workflows in the Cloud
Authors: Madhyastha Tara 
Published: December 2024

AbstractAnalysis of large neuroimaging datasets requires scalable computing power and storage, plus methods for secure collaboration and for reproducibility. The application of cloud computing can address many of these requirements, providing a very flexible model that is generally far less expensive than a lab trying to purchase the most computer equipment they would ever need. This chapter describes how researchers can change the way that they traditionally run neuroimaging workflows in order to leverage cloud-computing capabilities. It describes various considerations and options related to cloud-based neuroimaging analyses, including cost models and architectures. Next, using data from the AOMIC-PIOP2 project hosted on OpenNEURO, it shows how to use Nextflow to create a very simple skull stripping and tissue segmentation workflow using FSL’s bet and fast programs installed on a local computer. Nextflow allows scalability from a laptop to a cluster to cloud-native services with no code changes.
Optimizing Your Reproducible Neuroimaging Workflow with Git
Authors: Garcia Mélanie , Kelly Clare 
Published: December 2024

AbstractAs a neuroimager working with open-source software and tools, you will quickly become familiar with the website GitHub, which is a (for profit) platform for storing, managing, and sharing code, software, and projects. Many of the open-source tools discussed in this book are hosted on GitHub. Although people are generally very familiar with GitHub (or GitLab), they are often less familiar with its foundation—Git. Better understanding Git will help you better manage your own projects and will also help you to better understand GitHub and how to use it optimally. In this chapter, we will first explain Git and how to use it, then we will turn to GitHub. A worked example—a clustering analysis—with open access neuroimaging data is provided, demonstrating utilities such as version control, branching, and conflict resolution.
Theoretische Grundlagen
Authors: Scheiding Christian Thomas 
Published: December 2024

ZusammenfassungDie sinnhafte Beachtung und Darlegung von soliden theoretischen Grundlagen in der Wissenschaft sind essenziell für jegliche Form der Erkenntnisgenerierung, da sie eine gemeinsame Plattform für Verständnis und Diskussion bereitstellen und die Möglichkeit bieten, auf früheren Erkenntnissen und Theorien aufzubauen. Dieses Kapitel widmet sich explizit dieser Aufgabe mit dem Ziel, ein umfassendes theoretisches Fundament zu etablieren. Zunächst wird die grundlagentheoretische Rahmung gesetzt.
Methodologische Grundlagen und methodische Verfahren
Authors: Scheiding Christian Thomas 
Published: December 2024

ZusammenfassungIn diesem Kapitel werden die methodologischen Grundlagen und methodischen Verfahren, die für diese Forschungsarbeit verwendet werden, detailliert vorgestellt und deren Auswahl begründet. Zunächst wird auf das Erkenntnisinteresse, die Zielsetzung und die Fragestellung der Arbeit eingegangen, die den Rahmen für die nachfolgenden methodologischen und methodischen Betrachtungen abstecken und als Bindeglied zwischen der Theorie, dem aktuellen Stand der Forschung, den methodologischen Überlegungen und dem methodischen Forschungsdesign fungieren. Es wird auf das dialektische Verhältnis von Theorie, Methodologie und methodischen Verfahren Bezug genommen.
Conclusio
Authors: Scheiding Christian Thomas 
Published: December 2024

ZusammenfassungIn dieser Arbeit wurde der Themenkomplex der Nachhaltigkeit in den Organisationen des ÖD mit dem Fokus auf das nachhaltigkeitsrelevante Verhalten der Beschäftigten umfassend untersucht. Das Hauptziel der Untersuchung bestand darin, neue Theorie zum Verständnis und zur Klärung der Frage zu generieren, wie Angestellte des ÖD den wahrgenommenen Anforderungen des Konzepts der Nachhaltigkeit vor dem Hintergrund ihres beruflichen Alltags begegnen.
The terrestrial isopod Porcellionides pruinosus as a facultative ant guest along foraging trails and inside Messor ebeninus nests in the Negev Desert
Authors: Oxman K. , Kuabara K. M. D. , O’Donnell S. 
Published: December 2024

AbstractWe report field observations of the cosmopolitan terrestrial isopod species Porcellionides pruinosus both inside the nest and following foraging trails of the seed harvester ant Messor ebeninus in the spring of 2022 and 2023. The isopods inside the nest either traveled to deeper tunnels or joined foraging trails. The density of isopods along foraging trails was as high as 60 individuals along one 22-m foraging trail. The results from 12 preliminary homing assays revealed that the distance isopods were displaced did not affect whether they returned to the trail. Two of the four isopods introduced into a foraging trail of a new nest continued walking on the foreign trail. The isopods were met with minimal aggression from the ants along the trail, and there were no instances of nest guarding observed. The presence of P. pruinosus as a facultative associate inside M. ebeninus nests could be driven by a need for thermal refuge and access to subterranean granaries. The known ability of isopods to cue into ant pheromones is a plausible mechanism for allowing isopods to follow foraging trails. The benefit of trail following behavior needs further investigation. We hypothesize a benefit to walking on a path clear of obstacles, and efficient detection of patchy desert food sources.
Paleoproterozoic Mississippi Valley-type mineralization at Black Angel, Greenland: evidence from sulfide δ66Zn and rhenium-osmium geochronology
Authors: Saintilan Nicolas J. , Archer Corey , Szilas Kristoffer , Krüger Geertsen Kristina , Rosa Diogo , Spangenberg Jorge E. 
Published: December 2024

AbstractWe provide timestamps for the major zinc-lead (Zn-Pb) Mississippi Valley-type Black Angel deposit (Greenland) based on new pyrite rhenium-osmium (Re-Os) isotope geochemistry data: (1) a Re-Os isochron age 1,884 ± 35 million years ago (Ma – 2σ, 1.8%) for subhedral pyrite cemented by sphalerite ± galena in dolomitized clean limestone, and, (2) a Re-Os model age 1,828 ± 16 Ma (2σ, 0.9%) for epigenetic massive pyrite in siltstone/mudstone cap rock. Zinc-lead mineralization in evaporite-bearing carbonates in the Karrat Basin took place ca. 1,884 Ma at the time of far-field fluid flow associated with back-arc spreading ca. 1,900–1,850 Ma. Mineralization predates the development of the Rinkian foreland basin (ca. 1,850 – < 1,800 Ma) and a collisional stage (ca. 1,830 – < 1,800 Ma) in the context of the telescoping Rinkian and the Nagssugtoqidian Orogens. Replacement of clean carbonate and sustained acid neutralization led to significant sphalerite precipitation ca. 1,884 Ma. Conversely, precipitation of epigenetic massive pyrite in the cap rock ca. 1,828 Ma may signal (1) the lack of chemical reactivity of the cap rock for the pH-buffered conditions needed for Zn-Pb mineralization, and (2) the unfavorable impact of incipient regional Rinkian metamorphism (ca. 1,830–1,800 Ma) and tectonic compression on aquifer permeability and continued brine migration. The initial 187Os/188Os ratio (Osi-pyrite = 1.07 ± 0.32) from isochron regression identifies a crustal origin for Os and, by corollary, other metals in the ca. 1,884 Ma Zn-Pb mineralization. Although the Rae Craton basement rocks comprise the dominant source for metals (based on our Osi-pyrite and δ66Znpyrite/sphalerite data), we identify a complementary contribution in Zn (maximum 12–24%) from Paleoproterozoic sedimentary carbonate. This source of Zn in sedimentary calcite is deemed possible in the context of Paleoproterozoic seawater at high Na/Cl ratio and in the absence of Zn-based eukaryotic metabolism in shallow marine environment.
Topology optimization for 3D fluid diode design considering wall-connected structures
Authors: Sasaki Takamitsu , Furuta Kozo , Ishida Naoyuki , Li Hao , Kondoh Tsuguo , Izui Kazuhiro , Nishiwaki Shinji 
Published: December 2024

AbstractThis paper proposes a density-based topology optimization method for the three-dimensional design of fluid diodes considering wall-connected structures based on the fictitious physical modeling approach. The optimum design problem of fluid diodes is formulated as maximizing the energy dissipation in the reverse flow subject to the upper bound constraint of the energy dissipation in the forward flow. A fictitious physical model and a geometric constraint are constructed to detect and restrict the “floating” solid domains, which are not connected to the outer boundaries. The sensitivities of cost functions are derived and computed based on the continuous adjoint method. The finite volume method is employed to discretize the governing and adjoint equations to mitigate the huge computational costs of three-dimensional fluid analysis. Numerical investigations are presented to validate the fictitious physical model and the geometric constraint for excluding “floating” islands. Finally, topology optimization for fluid diodes with and without the geometric constraint is performed, and the result demonstrates that the proposed method is capable of generating fluid diodes with wall connectivity, while maintaining a good functional performance.
Tool pose measurement using shadow imaging sensors
Authors: Terlau Marina , von Freyberg Axel , Fischer Andreas 
Published: December 2024

AbstractDue to the high positioning uncertainty and low stiffness of robots, significant geometrical deviations occur in robotic incremental sheet forming (ISF) which requires an optical in-process tool pose measurement. To achieve a measuring uncertainty of less than 50 $$\upmu $$
μ
m for the position components and less than 0.05$$^\circ $$

∘

for the orientation components in the machining volume, a multi-sensor system based on shadow imaging sensors is proposed. To calculate the six-degree-of-freedom tool pose, the sensor system measures the positions of three LEDs attached to the tool. The LEDs emit light with different colors, and the associated shadows are separately detected by using color filters. In addition, each sensor consists of a shadow-casting mask and a monochrome camera. Experimental results show that the systematic error dominates the measurement uncertainty budget and needs to be calibrated, while the random error is one order of magnitude smaller than the required measuring uncertainty. Furthermore, the color filters reduce the cross-sensitivities between the signals to an acceptable level. Final experiments on a robot demonstrate plausible pose measurements indicating the feasibility to apply the multi-sensor system in robotic ISF.
Vulva Self-Image and Sexual Function After Female External Genital Plastic Surgery
Authors: Turini Tatiana , Sant Ana Geisa , Imoto Aline Mizusaki , Martins Maria Eduarda Alves 
Published: December 2024

Abstract
Introduction
Female external genital plastic surgery (vulvoplasty) is among the most performed aesthetic surgeries in Brazil. Vulva self-image can be defined as women's perception of their vulva and is usually related to sexual function. The objective of this study was to evaluate the impact and interrelationship of female external genital plastic surgery on self-image and sexual function.

Method
This quantitative longitudinal descriptive study includes a retrospective analysis of 48 medical records from June 2017 to July 2021. The sexual function questionnaire (SFQ-28) and female genital self-image scale (FGSIS) answered by the patients in the preoperative and six postoperative month were analyzed.

Result
The mean age of the operated patients was 36.25 years (range 18–59). The median FGSIS score was 13 in the preoperative and 27.5 in the six postoperative month, with a significant positive difference in all items. There was a significant positive difference in the following SFQ-28 domains: desire, arousal (cognitive), orgasm, enjoyment, and partner (p < 0.005)

Conclusion
In our cohort, female external genital plastic surgery (vulvoplasty) elicited a positive relationship between genital self-image and sexual function, in addition to improving orgasm.

Level of Evidence IV
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Einfluss des Behandlungssettings auf die Versorgung von Patient*innen mit rheumatoider Arthritis oder Psoriasisarthritis im Rahmen der Delegation an rheumatologische Fachassistenz — eine Post-hoc-Analyse der StärkeR-Studie
Authors: Shabani Rilind , Mai Anna , Denz Robin , Timmesfeld Nina , Braun Jürgen , Krause Dietmar 
Published: December 2024

Zusammenfassung
Hintergrund
Die StärkeR-Studie zeigte die Nichtunterlegenheit einer teambasierten Versorgungsform mit Delegation an rheumatologische Fachassistenz (RFA) gegenüber der Standardversorgung bei Patient*innen mit rheumatoider Arthritis (RA) oder Psoriasisarthritis (PsA).

Zielsetzung
Explorative Analysen hinsichtlich eines möglichen Einflusses des Behandlungssettings (Schwerpunktpraxis/Klinikambulanz) auf verschiedene Outcome-Parameter bei Patient*innen mit RA oder PsA im Rahmen der Delegation an rheumatologische Fachassistenz.

Material und Methoden
Patient*innen mit RA oder PsA und stabiler Einstellung bei geringer Krankheitsaktivität aus 3 Klinikambulanzen und 14 rheumatologischen Schwerpunktpraxen, die an der StärkeR-Studie teilgenommen hatten, wurden in diese Post-hoc-Analyse einbezogen. Die Effektivität der teambasierten Versorgungsform in Abhängigkeit vom Behandlungssetting wurde mittels Interaktionsanalysen in linearen Regressionsmodellen u. a. mit Blick auf Krankheitsaktivität, Funktionsfähigkeit, Schmerz und Müdigkeit untersucht.

Ergebnisse
Von 588 Patient*innen wurden 466 in Schwerpunktpraxen behandelt, 92 in Klinikambulanzen. Die Analysen ergaben bei einem von 9 untersuchten Endpunkten eine signifikante Interaktion: Die Funktionskapazität (Skala 0–1) zeigte in den Klinikambulanzen gegenüber der Standardversorgung gering niedrigere Werte (−0,07 [−0.12; −0.02]), während sich ein solcher Unterschied in den Praxen nicht darstellte. Bei anderen Endpunkten zeigte sich tendenziell ein Vorteil der teambasierten Versorgungsform im Praxissetting.

Diskussion
Diese explorativen Analysen weisen auf den möglichen Nutzen der Evaluation von verschiedenen Versorgungsformen wie der Delegation ärztlicher Leistungen an qualifizierte RFA im Sinne eines Benchmarkings hin.
Can wage changes solve the labour crisis in the National Health Service?
Authors: Zhou Xingzuo , Skordis Jolene , Yi Junjian , Li Yiang , Clarke Jonathan , Zhang Hongkun 
Published: December 2024

AbstractThis study aimed to examine the healthcare labour demand and supply elasticity regarding wage in the National Health Service (NHS) in England amid a labour crisis. A simultaneous error-correction regression analysis was conducted using secondary data from the NHS and Office for National Statistics from 2009 Q3 to 2022 Q1. Findings indicate both labour demand and supply of HCHS doctors in the NHS are highly inelastic with respect to real wages, with only a 0.1% decrease in NHS staff hiring and a 0.8% rise in NHS staff’s willingness to work as full-time equivalents per 10% wage increase. Approximately 22% of the wage disequilibrium adjusts quarterly, indicating moderate speed of wage adjustment. Our results suggest that wage setting is not a sufficient solution to the labour crisis. Innovative and sustainable solutions are needed to reduce the demand for skilled health labour and increase the supply of health labour.
Moderne Pharmakotherapie Erwachsener
Authors: Steinhoff Bernhard J. 
Published: December 2024

Zusammenfassung
Erfreulicherweise wurden im vergangenen Jahr nach langer Wartezeit die Leitlinien der Deutschen Gesellschaften für Neurologie und Epileptologie „Erster epileptischer Anfall und Epilepsien im Erwachsenenalter“ publiziert. Diese sorgfältig im Konsensverfahren erarbeiteten Ratschläge decken überwiegend die aktuelle Literatur und Praxisevidenz ab. Konsensbasierte Leitlinien haben den methodischen Nachteil, dass sie sich zwar nach der Evidenz richten, letztlich die Empfehlungen aber im Konsens gegeben werden, der in Würdigung der Sachlage und der Erfahrung der Experten richtig sein kann. Ein weiteres Problem von Leitlinien besteht darin, dass sie bei mäßiger Evidenzlage in der Literatur auch nur vage Empfehlungen ableiten kann, die in der Praxis wenig hilfreich sind. Die anfallssuppressive Pharmakotherapie stellt trotz aller Neuerungen auf den Gebieten der Epilepsiechirurgie, Neurostimulation und Diätbehandlung nach wie vor den Goldstandard der Epilepsietherapie dar. Neue Anfallssuppressiva und v.  a. hochrangige Studien zur Sicherheit und Verträglichkeit bereits vorhandener Medikamente haben die Möglichkeiten zu einer verbesserten Pharmakotherapie deutlich verbessert. Die hier vorgelegte Übersichtsarbeit fasst den aktuellen Stand der anfallssuppressiven Pharmakotherapie zusammen und kommentiert die sich hieraus ergebenden Praxisempfehlungen zum „state of the art“ in Ergänzung und im Lichte der Leitlinien.
On the Axial Symmetry of 2D Star-Shaped Sets
Authors: López-Díaz María Concepción , López-Díaz Miguel 
Published: December 2024

Abstract
An essential aspect of the study of shapes is the symmetry because of its importance from a theoretical point of view and its applicability in multiple real-life problems. In this manuscript, the axial symmetry of 2D star-shaped sets is analyzed. For such a purpose, different measures of axial symmetry of a star-shaped set are proposed and the concept of a best symmetry axis is also introduced. By means of them, families of symmetry measures for star-shaped sets quantifying the degree of symmetry of a set of that class are introduced. All of them are discussed in detail, providing their main properties and the existence of at least a best axis of symmetry, which could be not unique, for any star-shaped set. Some examples illustrate the concepts and results of the manuscript.
Cognitivism about religious belief in later Wittgenstein
Authors: Pichler Alois , Sunday Grève Sebastian 
Published: December 2024

Abstract
Wittgensteinian philosophy of religion has traditionally been grounded in non-cognitivism about religious belief. This paper shows that the Wittgensteinian tradition has wrongly neglected a significant movement towards cognitivism in Wittgenstein’s later writings. The argument proceeds on the basis of two main claims. First, Wittgenstein’s mature philosophy, as expressed in his Philosophical Investigations, clearly favours cognitivism over non-cognitivism with regard to certain linguistic facts about ordinary religious discourse. Second, during the last decade of his life Wittgenstein’s view of religious belief actually underwent a significant shift in the direction of cognitivism, which finds its most striking expression in the analogy he draws to the ‘honest religious thinker’.