bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumption among young activists
Authors: Arif Elvira M. 
Published: March 2019

There are two main approaches to study youth consumption. The first one considers consumption as viewed by a group of people of a certain age who differ from other age groups. Cultural differences are not taken into account. In the second approach consumption is seen as one of structure-forming elements of youth communities and practices. In that case, researchers study subcultures and youth leisure activities. However, those young people who are not engaged in subcultures and whose consumption patterns do not define their group identities are poorly studied. The article analyzes the importance of consumption among young persons and examines the ideological vectors of youth solidarity. The database consists of 28 biographical interviews with young activists from St Petersburg. The emphasis is placed on value priorities and the significance of labor for young activists. Thus, the meaning of consumption is considered through the prism of values and labor using the notion of “cultural repertoire of consumption”. Based on the interview results, five repertoires were singled out: anti-reconsumption, ethical, pro-Soviet, anti-consumption and politicized repertoires. Special attention is given to young activists’ reinterpretation of exclusiveness within the dominant consumption discourse. The analysis provides the grounds for reviewing the content of the solidarity vector and the substitution of “consumption - asceticism” direction for the “critical – internalized consumption”.
Acknowledgement. The author expresses gratitude to Elena L. Omelchenko, director of NRU HSE Center for Youth Studies, and Yana N. Krupets, project manager, for the provided materials. Special thanks go to all the colleagues who took part in the tool design and data collection, discussion and analysis.
Promoting mathematical reasoning and problem solving through inquiry-based relevance focused computer simulations: a stoichiometry lab
Authors: Gupta Tanya 
Published: March 2019

Abstract
Simulations model concepts and phenomena. Several researchers have called for an intuitive and user-friendly simulation design to foster conceptual understanding of users. Simulations can also be used to promote mathematical thinking and problem-solving skills of students in various chemistry courses. An example of such use of simulations would be teaching reaction stoichiometry and underlying dimensional analysis for determining the quantity of reactants and products involved in a chemical reaction. In this paper, the author presents an innovative model of a guided-inquiry based simulation for promoting mathematical thinking in chemistry by incorporating mathematical thinking as a component of simulation design. The simulation was implemented in an introductory organic chemistry laboratory course in which a significant gain in pre- and post-test was observed for participating students.
Progression of Meiosis Is Coordinated by the Level and Location of MAPK Activation Via OGR-2 in Caenorhabditis elegans
Authors: Achache Hanna , Laurent Lévana , Hecker-Mimoun Yaël , Ishtayeh Hasan , Rappaport Yisrael , Kroizer Eitan , Colaiácovo Monica P , Tzur Yonatan B 
Published: March 2019

Abstract
During meiosis, a series of evolutionarily conserved events allow for reductional chromosome division, which is required for sexual reproduction. Although individual meiotic processes have been extensively studied, we currently know far less about how meiosis is regulated and coordinated. In the Caenorhabditis elegans gonad, mitogen-activated protein kinase (MAPK) signaling drives oogenesis while undergoing spatial activation and deactivation waves. However, it is currently unclear how MAPK activation is governed and how it facilitates the progression of oogenesis. Here, we show that the oocyte and germline-related 2 (ogr-2) gene affects proper progression of oogenesis. Complete deletion of ogr-2 results in delayed meiotic entry and late spatial onset of double-strand break repair. Elevated levels of apoptosis are observed in this mutant, independent of the meiotic canonical checkpoints; however, they are dependent on the MAPK terminal member MPK-1/ERK. MPK-1 activation is elevated in diplotene in ogr-2 mutants and its aberrant spatial activation correlates with stages where meiotic progression defects are evident. Deletion of ogr-2 significantly reduces the expression of lip-1, a phosphatase reported to repress MPK-1, which is consistent with OGR-2 localization at chromatin in germ cells. We suggest that OGR-2 modulates the expression of lip-1 to promote the timely progression of meiosis through MPK-1 spatial deactivation.
Pleito pendiente internacional. Una mirada desde la Comisión Interamericana de Derechos Humanos
Authors: Gonz Andr 
Published: March 2019

ResumenEste artículo aborda el elemento de admisibilidad convencional y reglamentario de "no pleito pendiente internacional" y se propone para ello una investigación basica, descriptiva y deductiva, que parte de la pregunta (,Que debe entenderse por pleito pendiente internacional? y el objetivo general de identificar las lineas de argumentación de la comisión, cuando un Estado propone la inadmisibilidad de la petición por la existencia de un pleito pendiente; reconociendo que este implica que haya identidad entre las partes, el objeto, la base legal de la petición, y ademas, se tramite ante un órgano internacional cuyo mandato sea convencional y su procedimiento sea adjudicativo, contencioso y contradictorio. AbstractThis article address the "no international pending proceeding" conventional and statutory element of admissibility. Through a basic, descriptive and deductive research, and it born of the question What should be understood international pending proceeding? And the general objective of identifying the lines of argumentation of the Commission when a State proposes the inadmissibility of a petition based on the existence of a pending proceeding. As a result, we find out that we have a pending proceeding when there is an identity between the parties, the object, the legal foundation of the petition and, moreover, it is processed by an international body which has a conventional mandate and an adjudicative, contentious and contradictory procedure.
El enfoque de competencias en la formación del abogado para el siglo XXI
Authors: Clavijo C Darwin 
Published: March 2019

ResumenEl presente articulo de investigación es el resultado de una revisión teórica del concepto de competencias en la educación superior, para confrontar la forma como las universidades de Colombia estan actuando en la orientación dada a los programas de Derecho. La tendencia mundial, traida desde el Espacio Europeo de la Educación Superior (EEES), es la formación de profesionales orientados por el enfoque de las competencias. En Latinoamerica, se han desarrollado un conjunto de acciones con el fin de determinar las competencias generales y especificas propias de cada profesión; en el caso del Derecho el Proyecto Tuning, del que hicieron parte 65 instituciones de educación superior, presentó una propuesta de competencias especificas para la disciplina, las que categorizó en orden de importancia. En suma, es una Investigación en la que predomina el análisis documental armonizado con elementos propios de la investigación juridica, de naturaleza descriptiva, explicativa y expositiva. AbstractThis research report is the result of a study in which a theoretical review of the concept of competence in higher education was carried out to confront how Colombia's universities are acting on the guidance given to Law programs. The worldwide trend, brought from the European Higher Education Area (EHEA), is the training of professionals guided by the focus on compe- tencies. In Latin America, we have developed a set of actions in order to determine the general and specific competence for each profession; law in the case of the Tuning Project, in which 65 institutions of higher education were part of presented a proposal for the discipline specific competences, which were categorized in order of importance. Finally, It is a study in which predominates the harmonized document analysis with elements of legal, descriptive, exposi- tory and explanatory research.
La nacionalidad como un derecho humano: El caso Satya de Ecuador
Authors: Figuera Vargas Sorily Carolina , Robles Arias Johana 
Published: March 2019

La nacionalidad es un derecho humano universal consagrado en las principales convenciones internacionales vigentes en el continente americano. Luego que la Corte Constitucional del Ecuador dictó la Sentencia N° 184-18-SEP-CC, en fecha 29 de mayo de 2018, relativa al caso Satya, el siguiente análisis resulta relevante en cuanto al estudio de la nacionalidad, su definición, sus principios, su regulación internacional, cuáles han sido algunos de los criterios de la Corte Interamericana de Derechos Humanos en relación con esta figura jurídica y cómo Ecuador regula la nacionalidad en su sistema legal. Finalmente se procederá a la disertación sobre la mencionada sentencia en lo referente a la nacionalidad como derecho humano, su conexión con el derecho a la identidad y el interés suprior de las niñas y niños. Así pues, se desarrollará un método de investigación jurisprudencial para llegar a las conclusiones sobre este debate.
ANALISIS ISI LAMBUNG IKAN TAWES (Barbonymus gonionotus) DI HILIR SUNGAI BENGAWAN SOLO KABUPATEN LAMONGAN
Authors: Buwono Nanik Retno 
Published: March 2019

Analisis isi lambung ikan dapat memberikan gambaran antara komposisi pakan alami dalam lambung dengan habitatnya. Tujuan penelitian ini untuk mendeskripsikan mengenai makanan alami ikan Tawes (Barbonymus gonionotus) dengan melihat isi lambung ikan, pola pertumbuhan dan faktor kondisi ikan di bagian hilir Sungai Bengawan Solo Kabupaten Lamongan. Metode yang digunakan dalam penelitian ini adalah metode survei dengan pengambilan sampel dua minggu sekali selama 2 bulan. Hasil penelitian yang diperoleh menunjukkan bahwa ikan tawes merupakan ikan herbivora. Rasio panjang relatif usus ikan tawes berkisar antara 2,0-2,1 cm yaitu panjang usus ikan tawes lebih panjang dari panjang total tubuhnya yang menunjukkan ikan tawes bersifat herbivora. Frekuensi kejadian makanan ikan tawes didominasi dari jenis plankton Chlorophyta yaitu Akistrodesmus (100%) pada semua lambung yang teramati serta Ulotrix (94,4%) yang ditemukan di beberapa lambung yang teramati. Kisaran panjang tubuh ikan tawes antara 104,8-280,1 gram dan memiliki pola pertumbuhan allometrik negatif. Faktor kondisi pada ikan tawes betina dengan nilai rata-rata 1,4 dan pada ikan tawes jantan dengan nilai rata-rata 0,8. Faktor kondisi ikan tawes di Sungai Bengawan Solo memiliki faktor kondisi yang cukup tinggi hal ini berarti adanya kecocokan antara ikan dengan lingkungannya.
Gap Balancing, Measured Resection, and Kinematic Alignment
Authors: Mercuri John J. , Pepper Andrew M. , Werner Jordan A. , Vigdorchik Jonathan M. 
Published: March 2019

» Although total knee arthroplasty is a successful and well-established surgical intervention, there is renewed interest in evaluating its theoretical underpinning and surgical techniques in order to identify areas for potential improvement in patient outcomes.» The practice of using mechanical limb alignment for total knee arthroplasty arose from the design of the modern condylar knee prosthesis, with the goal of equally distributing stresses across the articulating surfaces of the prosthesis.» With the kinematic alignment technique, the restoration of normal joint kinematics is based on 3 goals: (1) restoring the native tibiofemoral articular surfaces, (2) restoring the native limb and knee alignment, and (3) restoring the native laxity of the knee.» With the gap-balancing technique, knee balance is primarily achieved through osseous resection and removal. Ligament releases may be necessary prior to completion of the bone resections in order to correct fixed deformities or to restore neutral mechanical alignment before determining component rotation.» With measured resection, either the femur or the tibia can be resected first and in its entirety because all bone resections are independent of one another. Bone resections are fixed on the basis of osseous landmarks, implant dimensions, and patient anatomy.
The effect of doping ratio of Cu on the structural properties of CdSe Films
Authors: Journal Baghdad Science 
Published: March 2019

Films of CdSe have been prepared by evaporation technique with thickness 1µm. Doping with Cu was achieved using annealing under argon atmosphere . The Structure properties of these films are investigated by X-ray diffraction analysis. The effect of Cu doping on the orientation , relative intensity, grain size and the lattice constant has been studied. The pure CdSe films have been found consist of amorphous structure with very small peak at (002)	plane. The films were polycrystalline for doped CdSe with (1&2wt%) Cu contents and with lattice constant (a=3.741,c=7.096)A°, and it has better crystallinty as the Cu contents increased to (3&5wt%) Cu. The reflections from [(002), (102). (110), (112), and (201)]planes are more prominent referring to hexagonal unit cell. Therefore the crystal structure of CdSe:Cu films are hexagonal at Cu content (pure, 1&2wt%)	with a sharpness and also in the hexagonal form at	(3&5wt%).The crystalline size were found to depend on concentration of doping materials, and it is varied between (20.3-81.4)nm and increased with Cu content.
Some blood parameters study in albino female mice orally given crude aqueous soy bean (Glycine max) seeds extract
Authors: Journal Baghdad Science 
Published: March 2019

The possible effect of the crude aqueous extract of soy bean seeds on some blood parameters (total count of red blood cells, white blood cell , (total and differential) blood platelates, packed cell volume and concentration of blood hemoglobin) was studied in 20 albino female mice which were allocated in four experimental groups (5 mice/group). The first group was orally treated with distilled water (control group) while the second, third and fourth group were given a concentration of 4%, 6% and 8% of the extract, respectively.
At the end of the daily gavaging, which lasted for 4 weeks, the animals were killed, after recording their life body weight, and blood samples were collected from each mice to study the effect of the extract on the above mentioned parameters.
Some of the active ingredients in the soy bean seeds extract were analytically tested. This test showed that the extract contained flavonoids and saponins.
The effect of the extract on the studied blood parameters is reflected by the following results:
1)	Significant (P
The Role of Social Parameters in the Choice of Address Forms used in Kinship domain in Punjab, Pakistan
Authors: Ramsha Ana , Hidayat Samrah 
Published: March 2019

This study examines the role of social parameters in the choice of address forms used in kinship domain in Punjab, Pakistan. The study targeted 140 respondents in order to test the impact of social factors along with the regional differences in the choices of address forms in kinship domain. Statistical analyses are done by applying t-test for gender in relation to choices of address forms and ANOVA for age, income, education and social class. The study finds out that there is a strong connection of different social parameters not only with language use and practice but also in choices and use of address forms especially in kinship relationships. Moreover, it is highlighted that gender does not influence in the choices of address forms, even the participants belonging to young and middle categories show no significant difference with regard to the choices of address form despite the fact that all the factors and parameters exert influence on the choices of address forms. Hence address forms as being one of the major traits of language and society is affected by all the social factors around and regional differences are also most important as they give identity and ethnicity to the society.
Toward a comprehensive explanatory model of reliance on alternatives to the tap: evidence from California's retail water stores
Authors: Pierce Gregory , Lai Larry 
Published: March 2019

AbstractBuilding on a recent increase in scholarly attention to the problem of tap water mistrust and resulting negative health impacts, we examine the relationship between neighborhood reliance on tap water alternatives and a range of explanatory factors. We model retail water store locations as a proxy for reliance on tap water alternatives in urbanized neighborhoods across California. Our study is unique in its inclusion of variables representing both compliance with primary and secondary water quality standards by publicly regulated drinking water systems serving particular neighborhoods, other water system attributes and the socioeconomic characteristics of neighborhoods. The location of retail water stores in urbanized neighborhoods does not appear strongly related to observed measures of water quality. Secondary contamination shows a weak relationship to tap alternative reliance, and primary contamination was not correlated with higher levels of tap alternative reliance. On the other hand, our research suggests that other socioeconomic factors, particularly country of birth, are associated with the prevalence of more water stores. Increasing reliance on tap water likely requires measuring and addressing secondary contamination found in distributional systems and premise plumbing, and more aggressive public education campaigns.
Pica: A Common Condition that is Commonly Missed - An Update Review
Authors: Leung Alexander K.C. , Hon Kam Lun 
Published: March 2019

Background:Pica is a common condition in childhood that is commonly missed.Objective:To familiarize physicians with the clinical evaluation and management of children with pica.Methods:A PubMed search was completed in Clinical Queries using the key term "pica" OR “dirteating”. The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews. Only papers published in English literature were included in this review. The information retrieved from the above search was used in the compilation of the present article.Results:Pica refers to the persistent, compulsive craving for and the ingestion of substances usually considered inedible and the behavior is discordant with cultural practices and continues beyond the normal developmental phase of occasional indiscriminate and experimental mouthing and swallowing over a period of at least one month. The condition is more common among children in lower socioeconomic classes and those who are mentally handicapped or emotionally deprived. Pica is a significant cause of anemia and lead poisoning. Pica generally resolves in children of normal intelligence after they have been trained to discriminate between edible and inedible items and proper supervision is provided. While relief of family economic and housing difficulties is an adjunct, attention to the individual’s emotional needs and stresses is of paramount importance. Children with iron deficiency anemia should be treated with iron replacement therapy. Complications such as gastrointestinal obstruction and lead poisoning should be promptly recognized and treated.Conclusion:Pica is often an overlooked phenomenon and its association with iron deficiency and lead poisoning has been known for centuries. The underlying cause and complications should be treated if possible. Primary care physicians should be aware of pica and proactively seek information about pica in patients that belong to the high-risk groups.
Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
Authors: Najem Sonia Abou , Khawaja Ghada , Hodroj Mohammad Hassan , Rizk Sandra 
Published: March 2019

Background:Colorectal Cancer (CRC) is a common cause of oncological deaths worldwide. Alterations of the epigenetic landscape constitute a well-documented hallmark of CRC phenotype. The accumulation of aberrant DNA methylation and histone acetylation plays a major role in altering gene activity and driving tumor onset, progression and metastasis.Objective:In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro.Results:Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. On the other hand, the sequential treatment of Caco-2 cells, first with DAC and then with SAHA, induced a synergistic anti-tumor effect with a significant enhancement of growth inhibition and apoptosis induction in Caco-2 cell line as compared to cells treated with either drug alone. Furthermore, the combination therapy upregulates protein expression levels of pro-apoptotic proteins Bax, p53 and cytochrome c, downregulates the expression of antiapoptotic Bcl-2 protein and increases the cleavage of procaspases 8 and 9; this suggests that the combination activates apoptosis via both the intrinsic and extrinsic pathways. Mechanistically, we demonstrated that the synergistic anti-neoplastic activity of combined SAHA and DAC involves an effect on PI3K/AKT and Wnt/β-catenin signaling.Conclusion:In conclusion, our results provide evidence for the profound anti-tumorigenic effect of sequentially combined SAHA and DAC in the CRC cell line and offer new insights into the corresponding underlined molecular mechanism.
TheKLF6Super Enhancer Modulates Cell ProliferationviaMiR-1301 in Human Hepatoma Cells
Authors: Ri KumChol , Kim Chol , Pak CholJin , Ri PhyongChol , Om HyonChol 
Published: March 2019

Background:Recent studies have attempted to elucidate the function of super enhancers by means of microRNAs. Although the functional outcomes of miR-1301 have become clearer, the pathways that regulate the expressions of miR-1301 remain unclear.Objective:The objective of this paper was to consider the pathway regulating expression of miR- 1301 and miR-1301 signaling pathways with the inhibition of cell proliferation.Methods:In this study, we prepared the cell clones that the KLF6 super enhancer was deleted by means of the CRISPR/Cas9 system-mediated genetic engineering. Changes in miR-1301 expression after the deletion of the KLF6 super enhancer were evaluated by RT-PCR analysis, and the signal pathway of miR-1301 with inhibition of the cell proliferation was examined using RNA interference technology.Results:The results showed that miR-1301 expression was significantly increased after the deletion of the KLF6 super enhancer. Over-expression of miR-1301 induced by deletion of the KLF6 super enhancer also regulated the expression of p21 and p53 in human hepatoma cells. functional modeling of findings using siRNA specific to miR-1301 showed that expression level changes had direct biological effects on cellular proliferation in Human hepatoma cells. Furthermore, cellular proliferation assay was shown to be directly associated with miR-1301 levels.Conclusion:As a result, it was demonstrated that the over-expression of miR-1301 induced by the disruption of the KLF6 super enhancer leads to a significant inhibition of proliferation in HepG2 cells. Moreover, it was demonstrated that the KLF6 super enhancer regulates the cell-proliferative effects which are mediated, at least in part, by the induction of p21and p53 in a p53-dependent manner. Our results provide the functional significance of miR-1301 in understanding the transcriptional regulation mechanism of the KLF6 super enhancer.