bluuebunny/crossref_metadata_2025_split huggingface dataset:
The new insight of tectonic setting in Sunda–Banda transition zone using tomography seismic. Case study: 7.1 M deep earthquake 29 August 2023
Authors: Hasanah Mia Uswatun , Supendi Pepen , Nugraha Andri Dian , Widiyantoro Sri , Syaifuddin Firman 
Published: November 2024

Abstract
The Sunda–Banda arc transition zone features the collision of the Indo-Australian oceanic plate and the Australian continent, resulting in intricate geological and geodynamic conditions. Tectonic activity in this region is shaped by the convergence of multiple major plates, including the Indo-Australian oceanic plate and the Eurasian plate. The crustal structure along the Sunda–Banda arc transition zone is complex and influenced by various factors such as subduction, continental collision, and volcanic activity. The tectonic complexity of the region in eastern Indonesia makes it an interesting area for study. In this research, International Seismological Centre-Engdahl-van der Hilst-Buland catalogue data from 1964 to 2020 were used, which include recorded information on 69.705 earthquake events from 1.185 recording stations and consist of 2.943.974 P phases. Resolution testing was performed using various velocity grids, and optimal results were obtained with a medium resolution of ∼100 km × 100 km × 80 km for the inversion process. The tomographic inversion analysis provided valuable insights into subsurface structures within Earth’s crust and mantle up to a depth of approximately 750 km. The occurrence of deep earthquakes in the study area has provided valuable insights into complex dynamics associated with subduction and plate tectonics. The results of the tomographic inversion analysis reveal that earthquakes are concentrated in areas with high-velocity anomalies, indicating intense tectonic activity near the subduction zone. This study offers the perspective on the structural complexities and earthquake origins in the Sunda–Banda arc transition zone following the 2023 Mw 7.1 Bali Sea earthquake, which occurred on August 29, 2023, at 02:55:32 UTC + 7, approximately 163 km northeast of Lombok, Indonesia. This earthquake was caused by slab pull activity from the Australian Plate and involved a combination of downward and oblique-normal movement. These characteristics indicate the convergence and interaction between tectonic plates in the subduction process occurring in the Bali Sea area. As a result, there have been frequent occurrences of various tectonic and volcanic activities including earthquakes of different magnitudes. These results highlight the significance of the high-velocity anomaly connected to this occurrence, offering valuable insights into seismic behaviour and tectonic phenomena in the region. The findings of this study indicate that the deep earthquakes in the Bali Sea may be induced by faulting due to the transformation of metastable olivine into denser spinel at significant depths, along with shear instability caused by phase transitions within Earth’s mantle layers. This theory proposes that stress-induced changes in phase can initiate shear instabilities and subsequently lead to deep earthquakes.
Eco-friendly RP-HPLC approach for simultaneously estimating the promising combination of pentoxifylline and simvastatin in therapeutic potential for breast cancer: Appraisal of greenness, whiteness, and Box–Behnken design
Authors: Mahgoub Samar M. , Alwaili Maha A. , Rudayni Hassan A. , Almalki Manal A. , Allam Ahmed A. , Abdel-Reheim Mustafa Ahmed , Mohammed Osama A. , Mohamed Mahmoud A. 
Published: November 2024

Abstract
Breast cancer affects millions of women worldwide. This study explores the potential of combining pentoxifylline (PTX) and simvastatin (SIM) as a treatment for breast cancer. We aimed to develop six sustainability tools using green and white metrics to evaluate the environmental impact of reversed-phase high-performance liquid chromatography (RP-HPLC) methods for analyzing and separating PTX and SIM in their pure forms. The tools include analytical GREEnness, green analytical procedure index, Complexgreen analytical procedure index, analytical greenness metric for sample preparation, blue applicability grade index, and the RGB 12 algorithm. For the separation, we used a Novapack C8 column (15 × 0.46 cm, 5 µm) at 25°C. The injection volume was 5.0 µL, the wavelength was set to 210 nm, and the total runtime was 5 min. We identified optimal chromatographic conditions efficiently using the Box–Behnken design with minimal trials. We investigated the effects of three factors on retention time and resolution: acetonitrile ratio, pH, and flow rate. We used overlay plots with a 60:40 ratio (v/v) of acetonitrile and bi-distilled water to forecast the most effective mobile phase. The calibration curves for PTX and SIM showed a correlation value of over 0.999 within the range of 5–60 µg·mL−1. The recovery rates ranged from 99.9% to 100.2%, indicating high accuracy. Our RP-HPLC technique proves to be reliable and efficient for the simultaneous estimation of multiple anticancer drugs. We evaluated the environmental sustainability of this approach using green and white metrics, and the recommended method has been thoroughly validated according to International Council for Harmonisation guidelines, making it highly reliable for analyzing new formulations.
Demographic characteristics of the endangered Barbary sheep Ammotragus lervia (Bovidae: Caprini) in the fenced Amassine reserve, Western High Atlas range, Morocco
Authors: Bachiri Hakim , Znari Mohammed 
Published: November 2024

Abstract
Population characteristics of the Barbary sheep Ammotragus lervia, the only wild caprine in Northwest Africa, were investigated in a captive population located in a 150-ha fenced area within the Amassine reserve, Morocco, created for promoting wildlife watching tourism. We analysed the population trend during 20 years since the introduction of 10 individuals in 1999. Using direct counting in March-April 2016 to 2019, before herd dispersal, we assessed population size, age-sex structure, birth and survival rates. We estimated survival rates from mortality analysis using exponential regression models. The population size exhibited fluctuations over time expressed by significant exponential equations. We observed three successive phases corresponding each to a fast-growing period followed by a sharp decline. Estimated population density ranged from 0.25 to 0.41 ind. ha−1. Adult sex ratio varied from 67 to 91 rams per 100 ewes. Juveniles and subadults comprised 27–43 % of the population, and adults, rams and ewes, represented 26–31 % and, 29–45 %, respectively. Birth rate varied from 14 to 73 lambs per 100 ewes. The survival rate during the postnatal year approximated 35 %. For adult rams, it was around 69 % year−1. Our findings would be helpful for developing a sustainable population management plan, and assessing potential reintroduction/restocking in other areas.
Sex differences in prognosis of primary bone cancer: a propensity score-matched study
Authors: Shi Rui , Tian Leilei , Li Chuang , Lin Fang , Luo Yi 
Published: November 2024

Abstract

Objectives
Sex differences in survival in primary bone cancer have not been fully explored. Hence, this study was conducted to investigate the impact of sex on survival outcomes in patients with primary bone cancer.

Methods
The Surveillance, Epidemiology, and End Results (SEER)-17 database was used to identify patients with primary bone cancer. One-to-one propensity score matching (PSM) was employed to balance baseline characteristics. Kaplan-Meier curves and log-rank tests were used to evaluate differences in cancer-specific survival (CSS) and overall survival (OS) between sexes. Multivariate Cox regression analysis was performed to verify the independent effect of sex on survival, and sensitivity analysis was performed to determine the robustness of the results.

Results
A total of 8,791 patients were included, with 4,928 males (56.1 %) and 3,863 females (43.9 %), and a median follow-up time of 38 months. After PSM, 3,812 males and 3,812 females were included in the study, with balanced baseline characteristics between the groups. Post-PSM, females show significantly better CSS (HR=0.88, 95 % CI, 0.81–0.96, p=0.004) and OS (HR=0.87, 95 % CI, 0.81–0.94, p<0.001) compared to males. In multivariable Cox regression, the female sex was identified as an independent protective factor for both CSS (HR=0.86, 95 % CI, 0.79–0.94, p<0.001) and OS (HR=0.83, 95 % CI, 0.77–0.89, p<0.001).

Conclusions
Based on the analysis of SEER data with a large sample size, this study revealed that female patients with primary bone cancer have significantly better survival compared to males.
The neurobiological mechanisms of photoperiod impact on brain functions: a comprehensive review
Authors: Halabian Alireza , Radahmadi Maryam 
Published: November 2024

Abstract
Variations in day length, or photoperiodism, whether natural or artificial light, significantly impact biological, physiological, and behavioral processes within the brain. Both natural and artificial light sources are environmental factors that significantly influence brain functions and mental well-being. Photoperiodism is a phenomenon, occurring either over a 24 h cycle or seasonally and denotes all biological responses of humans and animals to these fluctuations in day and night length. Conversely, artificial light occurrence refers to the presence of light during nighttime hours and/or its absence during the daytime (unnaturally long and short days, respectively). Light at night, which is a form of light pollution, is prevalent in many societies, especially common in certain emergency occupations. Moreover, individuals with certain mental disorders, such as depression, often exhibit a preference for darkness over daytime light. Nevertheless, disturbances in light patterns can have negative consequences, impacting brain performance through similar mechanisms albeit with varying degrees of severity. Furthermore, changes in day length lead to alterations in the activity of receptors, proteins, ion channels, and molecular signaling pathways, all of which can impact brain health. This review aims to summarize the mechanisms by which day length influences brain functions through neural circuits, hormonal systems, neurochemical processes, cellular activity, and even molecular signaling pathways.
Tracing fashion transformations: a comprehensive visual analysis of fashion magazine covers
Authors: Seferoğlu Tuğba , Gülcü Yıldız Şerife 
Published: November 2024

Abstract
This study looks at the differences and changes observed in the visual design of the covers of French editions of women’s fashion magazines over a period of twenty-one years. To this end, the study aims to identify the changes that can be observed over the years in the design of the covers of the magazines Vogue, Elle, Marie Claire, and Cosmopolitan. However, the main aim of the study is to analyze how these visual signs on the covers of French magazines are designed “differently” and how these signs create a “difference” in comparison to each other. By analyzing these visual elements, the aim of the study is to show the development of design trends and their impact on the visual communication strategies and brand identities of magazines.
ZIF-67 derived N doped carbon embedded CoxP for superior hydrogen evolution
Authors: Panneerselvam Mohana , Yuvakkumar Rathinam , Ravi Ganesan , Mariyappan Thambidurai , Arunmetha Sundaramoorthy , Muthumareeswaran Paulpandian , Velauthapillai Dhayalan 
Published: November 2024

Abstract
Developing a sustainable non-noble hybrid electrocatalyst for effective electrocatalysis is the most crucial task; particularly in sustainable hydrogen energy production in the realm of energy conversion. In this work, effective thermal pyrolysis process followed by phosphorization strategy was employed to prepare and fabricate ZIF-67 (Zeolitic imidazole) assisted Co2P/N doped carbon electrocatalyst for hydrogen evolution reaction (HER). The optimized Co2P/N–C electrocatalyst exhibited hollow porous nanostructures as confirmed from the scanning electron microscopy. The achieved porous nanostructure improved the efficiency of the charge and mass transportation which is confirmed by the BET analysis, has high surface area value of 94.731 m2/g. In addition, a transition metal atom can regulate reactants adsorption and desorption capacity by modulating Co and P electronic configuration. The electrochemical studies of fabricated ZIF-67 derived Co2P/N–C electrode were analyzed using 1.0 M alkaline potassium hydroxide (KOH) medium in 3 electrode system process. Whilst, optimizing the pyrolysis temperature during the phosphorization will remarkably enhance the favourable characteristics of the hydrogen generation. Notably, the optimized ZIF-67 derived Co2P/NC at 350 °C electrode exhibited low overpotential (135 mV) at minimum 10 mA/cm2 and low 120.3 mV/dec Tafel slope. Besides, electrode stability at 10 mA/cm2 current density was verified by chronoamperometry test. Hence, this study furnishes the potential technique for the development of advanced hybrid MOF electrocatalyst as a successful alternative on large scale.
The influence of glycine on β-lactoglobulin amyloid fibril formation – computer simulation study
Authors: Jaklin Matej , Brudar Sandi , Hribar-Lee Barbara 
Published: November 2024

Abstract
Amyloids are protein aggregates involved in various protein condensation diseases. Our study aims to investigate the influence of glycine on the fibrillization mechanism of β-lactoglobulin (BLG), a model protein known to form amyloid fibrils from hydrolysed peptides in low pH aqueous solutions. We conducted atomistic molecular dynamics simulations of aqueous solutions of native and unfolded BLG in glycine buffer at pH 2.0. During the simulations we put our focus on analysing protein-protein/buffer interactions, structural electrostatic potential mapping, and the residence times of glycine and glycinium near specific amino acid residues. Glycinium cations were found to preferentially interact with specific protein residues potentially masking the outer disulfide bonds, affecting thiol deprotonation and influencing disulfide scrambling equilibrium. These interactions can potentially hinder hydrolysis and change the fibrillization pathway. Further investigations, such as constant pH MD simulations, simulations on disulfide bounded oligomers are warranted to validate these findings and deepen our understanding of protein aggregation mechanisms.
YÖNETİCİ HEMŞİRELERİN ÖFKE DÜZEYİ VE İFADE TARZININ HİZMET KALİTESİNE ETKİSİ
Authors: ÇORUH Fatma , AKTÜRK Altay İltan 
Published: November 2024

Hemşirelerin öfkelerini tanımamaları ve öfke ile ilişkili enerjiyi sağlıklı bir şekilde kullanmamaları neticesinde kurumun verimliliği ve kalitesi hem sağlıkları hem de kurumdaki verimlilikleri nedeni ile kalite ve performansını olumsuz etkilenmektedir. Bu nedenle, kurum tarafından verilen sağlık hizmetinin kalitesi, kurumun başarısı, kurumun güvenliği, kendi sağlığı ve performansı araştırılırken, yönetici hemşirelerin öfke ve öfkelerini ifade etmelerine ilişkin tutumlarının öğrenilmesinin önemli olduğu düşünülmektedir. Bu çalışmada; bu amaç doğrultusunda yönetici hemşirelerde öfke ve hizmet kalitesine yansıması konusunda değerlendirme yapmak için araştırma sonucunda çıkan bulguları kaliteye yorumlamak amaçlanmıştır. 224 yönetici hemşirenin katılımı ile yapılan araştımada; yapılan korelasyon analiz sonucunda; Sürekli Öfke Boyutu ve sağlıkta hizmet kalitesi ile %6.4 oranında negatif yönde (azaltıcı) anlamlı ilişki, Kontrol Altına Alınmış Öfke Alt Boyutu ve sağlıkta hizmet kalitesi ile %35,3 oranında pozitif yönde (artırıcı) anlamlı ilişki, Dışa Vurulan Öfke Alt Boyutu ve sağlıkta hizmet kalitesi ile %8.8 oranında negatif yönde (azaltıcı) anlamlı ilişki ve son olarak İçte tutulan öfke alt boyutu ve sağlıkta hizmet kalitesi ile %9.8 oranında negatif yönde (azaltıcı) anlamlı ilişkili tespit edilmiştir. Regresyon analizi sonucuna göre sürekli öfke ve sağlıkta hizmet kalitesi negatif yönlü anlamlı ilişkili, kontrol altına alınmış öfke ve sağlıkta hizmet kalitesi pozitif yönlü anlamlı ilişkili, Dışa vuran öfke ve sağlıkta hizmet kalitesi negatif yönlü anlamlı ilişkili ve son olarak İçte tutulan öfke ve sağlıkta hizmet kalitesi negatif yönlü anlamlı ilişkili tespit edilmiştir.
Demographic and clinical profile of patients with acute biliary pancreatitis: an experience in Patan academy of health sciences
Authors: Duwal Santosh , Suwal Bikesh , Maharjan Santabir , Bhandari Upendra 
Published: November 2024

Background: Acute pancreatitis is one of the most common causes of acute abdomen encountered in emergency department with wide range of severity from mild self-limiting disease to severe and rapidly progressive illness leading to multi organ failure and even death. Gall stones are leading cause of acute pancreatitis. This study has been carried out to find out demographic pattern and clinical profile of patients with acute biliary pancreatitis.
Methods: This is a prospective cross-sectional study carried out in the department of surgery in Patan academy of health sciences (PAHS) in the time period between May 1, 2021 and April 30, 2022. The process of data collection was started after obtaining ethical approval from institutional review committee (IRC) of PAHS, and written informed consent was obtained from patients. Total sampling was done and 66 patients were enrolled into the study, who were diagnosed as acute biliary pancreatitis. Data was analyzed with SPSS ver 25 and Microsoft excel 2016.
Results: Out of total 66 patients in the study 25 (37.9%) were male and 41 (62.1%) were female with male: female ratio of 1:1.64. Mean age was 48.42±16.62 years. ranging from 16-88 years. Epigastric abdominal pain was predominant presenting symptoms accounting for 57 (86.4%) cases. Pleural effusion was most common complication seen in 17 (25.8%) cases. Mortality occurs in 2 (3%) cases, both of cases had severe pancreatitis. Only 21 (31.8%) patients underwent cholecystectomy among which 13 (19.7%) interval and 8 (12.1%) index cholecystectomy.
Conclusions: Female gender with age group of 40-60 years. predominates acute biliary pancreatitis. Though most of the cases are mild and have benign course, severe cases and patients with advanced age are associated with high mortality. Acceptance of index cholecystectomy is very low.
3D imaging techniques for the diagnosis and surgical planning of complex limb fractures: a systematic review
Authors: Vera Mateo Daniel Fabara , Dávila David Alejandro Delgado , Valdés Claus André James , Zambrano Karen Nohelia Mora , Chimbo Narcisa de Jesús Patín , Montero Fabian Gabriel Salas 
Published: November 2024

This systematic study will investigate how 3D imaging techniques have improved diagnosis and planning of surgeries for complex limb fractures. These fractures are caused of high-energy trauma which presents unique challenges, so advanced imaging technologies can help to mitigate them. We strictly adhere PRISMA guidelines to ensure thorough analysis and inclusion of relevant literature. The search was conducted on Web of Science and PubMed were all thoroughly searched between 2010 and 2023. Keyword combinations such as "3D imaging," "complex limb fractures," and "surgical planning" were employed using Boolean operators and as a result, 26 studies were included following screening based on strict inclusion criteria. 56% of studies used CT scans, demonstrating a 32% increase in diagnosis accuracy over 2D techniques for complicated fractures. In 28% of cases MRI improved soft tissue evaluation. 3D printing was utilized in 16% of investigations and it improved postoperative alignment in 94% of cases and shortened operating times by 18%. We can conclude that 3D imaging greatly enhances surgical planning, patient outcomes, and diagnostic precision in complex limb fractures and it provides useful resources for surgeons and patients by improving fracture visualization, reducing operating time, and promoting quicker recovery.
The power of women in the success of business family: A case study of Kosovo, Albania and North Macedonia
Authors: Gashi Rrezarta , Smajlaj Violeta 
Published: November 2024

The main objective of this research is to emphasize the significant role women hold in leading family businesses in transitional countries such as Kosovo, North Macedonia, and Albania. It aims to demonstrate how women’s leadership can positively influence business performance, economic advancement and social development in these regions where traditional gender norms are shifting. Additionally, this study explores how empowering women in leadership roles can foster innovation, strengthen resilience, and ensure long-term sustainability for family-owned businesses ultimately contributing to the broader economic progress of these transitioning economies. This research aims to analyze family support, cultural factors and the influence of education on the advancement of women in leadership positions with a particular focus on family businesses. In this empirical research, 490 women from the countries above were included and the sample was randomly selected due to a lack of formal data. The results of the analyses were presented through descriptive analysis, Pearson correlation, Ordinary Least Squares (OLS) and T-test. The results indicate that family support has already a significant impacted advancement. Similarly, cultural factors have a positive influence. These factors have changed and are no longer obstacles to women's advancement as in the past, although in some rural countries this is still seen as an obstacle. Another important factor is education where women prioritize before taking leadership positions and continue with various training even after taking positions to be fully prepared to achieve their business objectives.
Development of circulatory system mobile learning (CSML) for grade XI students
Authors: Kumalasari Anggi Prastiwi , Harlita  , Rinanto Yudi 
Published: November 2024

The utilization of communication devices such as mobile phones as a learning support tool in the development of technology 4.0 is still low. The low mobile phone utilization as a learning support tool causes the variety of learning media used by teachers to be low. The low variety of learning media results in students having difficulty mastering the concept of learning material, especially circulatory system material in class XI. The difficulty of concept mastery on circulatory system material can be overcome through the development of circulatory system mobile learning (CSML). The research objectives are: 1) Develop CSML on circulatory system material in grade XI, 2) Test the feasibility of CSML, and 3) Know the response of teachers and students to CSML. The type of research is Research and Development (R&D) using the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). Data collection uses feasibility validation questionnaires and response questionnaires. The data analyzed were the results of the feasibility assessment from media experts and material experts, and the results of responses from teachers and students. Data analysis was carried out quantitatively descriptive using a Likert scale of 1-4. The results of the study are 1) The result of developing CSML can be accessed online; 2) The results of the feasibility assessment from media experts were 82.27% and material experts were 89.59% with a very feasible category; 3) The results of teacher responses were 87.02% and student responses were 88.55% with a great category.