bluuebunny/crossref_metadata_2025_split huggingface dataset:
Representaciones y prácticas de escritura en el contexto latinoamericano. Estado del tema
Authors: MORENO PINEDA VÍCTOR ALFONSO 
Published: July 2018

Este artículo de revisión presenta el estado de la cuestión de las investigaciones sobre representaciones y prácticas de escritura en el contexto latinoamericano. Se recogen diez investigaciones sobre representaciones sociales de la escritura y catorce investigaciones sobre prácticas de escritura, adelantadas en diversos contextos socioculturales. La información fue recabada de los repositorios Redalyc, Dialnet y Scielo y de revistas especializadas; solo se tuvieron en cuenta artículos de investigación que tuvieran explícitamente la estructura introducción, marco teórico, metodología, resultados y conclusión. Para organizar la información, se diseñó una matriz analítica de contenido. Esta matriz sirvió para extraer la información relevante y organizarla en las categorías analíticas definidas a priori: objetivos, teorías, métodos y resultados. Este documento comprende tres apartados. Primero, se explica la metodología utilizada para sistematizar la información de los artículos. Después, se presentan las categorías analíticas en que se organizó el estado del tema. Y por último, se expone una discusión sobre las tendencias generales de los trabajos reseñados y se ofrecen algunas reflexiones sobre alternativas y proyecciones investigativas en el campo de las representaciones sociales y prácticas de escritura.
La escritura académica en contexto: posibilidad de desarrollo profesional de profesores universitarios
Authors: HERNÁNDEZ VARGAS ELIZABETH , MARÍN CANO MARTHA LILIANA 
Published: July 2018

La investigación a la que se hace referencia en el presente artículo, corresponde a los resultados de un análisis documental (Galeano, 2012) de “La escritura académica en contexto: posibilidad de desarrollo profesional de los profesores universitarios”. El estudio pretende, por un lado, identificar a través de las investigaciones en escritura académica las diversas perspectivas teóricas y metodológicas, y, por otro lado, analizar la relación que existe entre escritura académica y el desarrollo profesional del profesor de educación superior. Con esta finalidad, se analizaron 50 documentos que datan del año 2006 hasta el año 2016 y que han sido publicados en diferentes países, tales como Chile, Colombia, México, Portugal, Argentina, Venezuela, Estados Unidos, España y Canadá. Los resultados muestran el interés de los investigadores por las dificultades que existen en el proceso escritor, la formación escritural del profesor universitario, la escritura como una tarea compleja, el uso de la escritura académica, las explicaciones a los problemas de lectura y escritura en el estudiante dejando de lado a los profesores, y el aprendizaje de los estudiantes y la didáctica de los profesores.
Estrategias pragmático-discursivas en escritos de calificación provisional y defensa en juicio oral
Authors: CERVERA RODRÍGUEZ ÁNGEL , TORRES ÁLVAREZ JOSÉ 
Published: July 2018

Esta investigación tiene como objetivo explicar el funcionamiento de las estrategias pragmáticas y dialécticas en el discurso forense, además de describir la interacción comunicativa entre la parte acusada y la acusadora, para determinar qué estrategias lingüístico-pragmáticas utilizan los abogados de la acusación y de la defensa a fin de convencer al juez de que avale la culpabilidad o inocencia del acusado. El corpus está formado por el escrito de conclusiones de calificación provisional y defensa en un juicio oral celebrado en los juzgados penales de Barcelona en 2010. Para conseguir este objetivo, se ha procedido a identificar los componentes lingüísticos y los indicadores dialéctico-argumentativos a los que recurren las partes en sus intervenciones, siguiendo una metodológica basada en la teoría pragmadialéctica, la etnometodología, la argumentación y la (des)cortesía. Entre los resultados destacan la nominalización, la recurrencia léxica y gramatical y los indicadores deícticos personales y operadores discursivos. A estas estrategias se unen las derivadas de la imagen que proyecta cada parte donde entra el juego de la cortesía o la descortesía.
Análisis de accesibilidad y conectividad de la red vial intermunicipal en el micro-sistema regional de la provincia Centro en Boyacá, Colombia
Authors: Bautista Andrés Felipe 
Published: July 2018

Se analiza la red vial intermunicipal del microsistema regional de la provincia Centro en el departamento de Boyacá, a través de la combinación de diferentes indicadores del análisis de redes, la teoría de grafos y de herramientas de los Sistemas de Información Geográfica como un instrumento útil al conocimiento de la funcionalidad, centralidad y desequilibrios presentes de su configuración espacial. Del análisis se obtiene una imagen de la densidad de accesibilidad relativa que permite estimar los escenarios de accesibilidad real e ideal, identificando patrones espaciales que ponen de presente el grado de desintegración y desigualdades territoriales en términos de las características topológicas de la red vial de transportes.
Scapular Notching After Reverse Total Shoulder Arthroplasty
Authors: Kolmodin Joel , Davidson Iyooh U. , Jun Bong Jae , Sodhi Nipun , Subhas Naveen , Patterson Thomas E. , Li Zong-Ming , Iannotti Joseph P. , Ricchetti Eric T. 
Published: July 2018

Background:
Scapular notching is frequently observed following reverse total shoulder arthroplasty (rTSA), although the etiology is not well understood.

Methods:
Twenty-nine patients with preoperative computed tomography (CT) scans who underwent rTSA with a Grammont design were evaluated after a minimum of 2 years of follow-up with video motion analysis (VMA), postoperative three-dimensional (3D) CT, and standard radiographs. The glenohumeral range of motion demonstrated by the VMA and the postoperative implant location on the CT were used in custom simulation software to determine areas of osseous impingement between the humeral implant and the scapula and their relationship to scapular notching on postoperative CT. Patients with and without notching were compared with one another by univariable and multivariable analyses to determine factors associated with notching.

Results:
Seventeen patients (59%) had scapular notching, which was along the posteroinferior aspect of the scapular neck in all of them and along the anteroinferior aspect of the neck in 3 of them. Osseous impingement occurred in external rotation with the arm at the side in 16 of the 17 patients, in internal rotation with the arm at the side in 3, and in adduction in 12. The remaining 12 patients did not have notching or osseous impingement. Placing the glenosphere in a position that was more inferior (by a mean of 3.4 ± 2.3 mm) or lateral (by a mean of 6.2 ± 1.4 mm) would have avoided most impingement in the patients’ given range of motion. Notching was associated with glenosphere placement that was insufficiently inferior (mean inferior translation, −0.3 ± 3.4 mm in the notching group versus 3.0 ± 2.9 mm in the no-notching group; p = 0.01) or posterior (mean, −0.3 ± 3.5 mm versus 4.2 ± 2.2 mm; p < 0.001). Two-variable models showed inferior and posterior (area under the curve [AUC], 0.887; p < 0.001), inferior and lateral (AUC, 0.892; p < 0.001), and posterior and lateral (AUC, 0.892; p < 0.001) glenosphere positions to be significant predictors of the ability to avoid scapular notching.

Conclusions:
Osseous impingement identified using patients’ actual postoperative range of motion and implant position matched the location of scapular notching seen radiographically. Inferior, lateral, and posterior glenosphere positions are all important factors in the ability to avoid notching. Only small changes in implant position were needed to avoid impingement, suggesting that preoperative determination of the ideal implant position may be a helpful surgical planning tool to avoid notching when using this implant design.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Trabecular Metal Versus Non-Trabecular Metal Acetabular Components and the Risk of Re-Revision Following Revision Total Hip Arthroplasty
Authors: Matharu Gulraj S. , Judge Andrew , Murray David W. , Pandit Hemant G. 
Published: July 2018

Background:
Studies have suggested that Trabecular Metal (TM)-coated acetabular components may reduce implant failure following revision total hip arthroplasty. However, these studies have predominantly been limited to small, single-center cohorts, with many lacking a comparator group. Using National Joint Registry data from England and Wales, we compared re-revision rates following revision total hip arthroplasty between TM and non-TM-coated acetabular components from 1 manufacturer.

Methods:
This retrospective observational study included all revision total hip arthroplasties performed with use of 1 of 4 cementless acetabular components produced by the same manufacturer (Zimmer Biomet). The acetabular components either had a TM surface coating (TM Modular and Continuum designs) or a non-TM surface coating (Trilogy and Trilogy IT designs). Revision total hip arthroplasties with TM and non-TM implants were matched for multiple potential patient and surgical confounding factors using propensity scores. Outcomes following revision total hip arthroplasty (re-revision for all acetabular indications, aseptic acetabular loosening, or infection) were compared between matched groups using competing risk regression analysis. Analyses were repeated in a subgroup initially revised for infection.

Results:
Of 3,862 matched revision total hip arthroplasties (1,931 in the TM group and 1,931 in the non-TM group), the overall prevalence of acetabular re-revision (2.7%; 95% confidence interval [CI] = 2.1% to 3.2%), re-revision for aseptic acetabular loosening (0.96%; 95% CI = 0.68% to 1.3%), and re-revision for infection (1.4%; 95% CI = 1.0% to 1.8%) were low. Six-year rates of re-revision for all causes (subhazard ratio [SHR] = 0.91; 95% CI = 0.61 to 1.35; p = 0.636), aseptic acetabular loosening (SHR = 1.32; 95% CI = 0.68 to 2.53; p = 0.410), and infection (SHR = 0.68; 95% CI = 0.39 to 1.20; p = 0.165) were similar between revision total hip arthroplasties with TM and non-TM coatings. Of 247 total hip arthroplasties initially revised for infection (116 TM and 131 non-TM), the rates of re-revision for all causes (SHR = 0.48; 95% CI = 0.15 to 1.56; p = 0.225), aseptic acetabular loosening (SHR = 0.54; 95% CI = 0.05 to 5.74; p = 0.608), and infection (SHR = 0.82; 95% CI = 0.28 to 2.36; p = 0.706) were similar between the TM and non-TM groups.

Conclusions:
Following revision total hip arthroplasty, TM-coated acetabular components had a low risk of both aseptic and septic re-revision, with rates that were comparable with those of non-TM components. Extended follow-up of large revision total hip arthroplasty cohorts will establish whether TM components have any clinical benefit over non-TM designs when used in patients with similar acetabular bone stock.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Increased Postoperative Glucose Variability Is Associated with Adverse Outcomes Following Total Joint Arthroplasty
Authors: Shohat Noam , Restrepo Camilo , Allierezaie Arash , Tarabichi Majd , Goel Rahul , Parvizi Javad 
Published: July 2018

Background:
Increased glucose variability during hospitalization has been associated with a longer length of stay in the hospital and a higher mortality rate following non-orthopaedic surgical procedures. Our aim was to investigate the association between glucose variability and postoperative complications following total joint arthroplasty.

Methods:
We analyzed data on 21,487 patients who had undergone total hip arthroplasty (THA) or total knee arthroplasty (TKA) at a single center from 2001 to 2017. Patients with a minimum of 2 postoperative glucose values per day or >3 values overall were included in the study. Glucose variability was assessed using a coefficient of variation. Adverse outcomes included an increased length of stay in the hospital, 90-day mortality, reoperations, periprosthetic joint infection, and surgical site infection. Periprosthetic joint infection was defined using the Musculoskeletal Infection Society criteria.

Results:
The final cohort included 2,360 patients who had undergone THA and 2,698 who had undergone TKA; 1,007 (19.9%) had diabetes. Higher glycemic variability was associated with an increased length of stay, 90-day mortality, periprosthetic joint infection, and surgical site infection. Adjusted analysis indicated that for every 10-percentage-point increase in the coefficient of variation, the length of stay increased by 6.1% (95% confidence interval [CI], 5.1% to 7.2%; p < 0.001), the risk of mortality increased by 26% (odds ratio [OR] = 1.26, 95% CI = 0.98 to 1.61; p = 0.07), and the risks of periprosthetic joint infection and surgical site infection increased by 20% (OR = 1.20, 95% CI = 1.02 to 1.41; p = 0.03) and 14% (OR = 1.14, 95% CI = 1.00 to 1.31; p = 0.06), respectively. These associations were independent of the year of surgery, age, body mass index, Elixhauser comorbidity index, diagnosis of diabetes, in-hospital use of insulin or steroids, and mean glucose values during hospitalization.

Conclusions:
Higher glucose variability in the postoperative period is associated with increased rates of surgical site and periprosthetic joint infections and may be a useful predictor of the risk of mortality following THA and TKA. Efforts should be made to control the glucose variability in the early postoperative period, and future studies should examine the role of continuous glucose monitoring in a subset of patients with high glucose fluctuations.

Level of Evidence:
Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
A Classification for Kyphosis Based on Column Deficiency, Curve Magnitude, and Osteotomy Requirement
Authors: Rajasekaran S. , Rajoli Sreekanth Reddy , Aiyer Siddharth N. , Kanna Rishi , Shetty Ajoy Prasad 
Published: July 2018

Background:
There is a lack of a classification system providing uniformity in description and guiding management decisions for kyphotic spinal deformities. We developed such a classification based on column deficiency, flexibility of disc spaces, curve magnitude, and correlation with the corrective osteotomy required.

Methods:
A classification was developed based on analysis of 180 patients with thoracolumbar kyphosis requiring osteotomy. The deformity was classified as Type I if the anterior and posterior columns were intact (IA indicated mobile disc spaces and IB, ankylosed segments). Type II indicated deficiency of only 1 column (IIA = anterior column and IIB = posterior column). Type III indicated deficiency of both columns (IIIA = kyphosis of ≤60°, IIIB = kyphosis of >60°, and IIIC = buckling collapse). A prospective analysis of 76 patients was performed to determine interobserver variability and the ability of the classification to guide selection of osteotomies of increasing complexity, including the Ponte osteotomy, pedicle subtraction osteotomy, disc bone osteotomy, single vertebrectomy, multiple vertebrectomies, and anterior in situ strut fusion procedure.

Results:
The mean age of the 76 patients was 21.2 years, the mean kyphosis was 69.9° (range, 26° to 120°), and the mean follow-up duration was 30 months. Six deformities were classified as IA, 5 as IB, 5 as IIA, 2 as IIB, 13 as IIIA, 35 as IIIB, and 10 as IIIC. Four surgeons classifying the deformities had a high agreement rate (kappa = 0.83), with the highest agreement for Types IA, IB, and IIIB. A correlation between the type of deformity and the osteotomy performed demonstrated that the classification could indicate the type of osteotomy required. All 18 patients with Type-I or II kyphosis were treated with Ponte, pedicle subtraction, or disc bone osteotomy. Forty-three (90%) of the 48 patients with Type IIIA or IIIB underwent vertebrectomy (single in 27 [56%] and multiple in 16 [33%]), and only 5 (10%) underwent disc bone osteotomy. Seven of the 10 patients with Type-IIIC kyphosis were treated with multiple vertebrectomies, with 5 of them needing preoperative halo gravity traction; the other 3 patients underwent an anterior in situ strut fusion procedure.

Conclusions:
The proposed classification based on the morphology of column deficiency, flexibility, and curve magnitude demonstrated a high interobserver agreement and ability to guide selection of the appropriate osteotomy.

Clinical Relevance:
A novel classification system for kyphosis based on spinal column deficiency, flexibility of disc spaces, and curve magnitude would bring uniformity in management and help guide surgeons in the choice of the appropriate corrective osteotomy.
Percutaneous Needle Fasciotomy Versus Collagenase Treatment for Dupuytren Contracture
Authors: Strömberg Joakim , Ibsen Sörensen Allan , Fridén Jan 
Published: July 2018

Background:
Local disruption of the cord that causes contracture of the finger in Dupuytren disease can be achieved either through mechanical division by percutaneous needle fasciotomy (PNF) or through enzymatic digestion by injectable collagenase Clostridium histolyticum (CCH). This study was designed to compare clinical and patient-reported outcomes between patients who had been treated with each method.

Methods:
A prospective, randomized, single-blinded, controlled trial was designed and included 156 patients with a contracture of the metacarpophalangeal (MCP) joint of ≥20°. The patients were allocated to treatment with either PNF or CCH. The primary outcome was a reduction of the MCP contracture to <5°. Secondary outcomes included the reduction of any concomitant contracture of the proximal interphalangeal (PIP) joint, the presence of Dupuytren cords, and changes in patient-reported outcomes as measured with the URAM (Unité Rhumatologique des Affections de Main) and QuickDASH (an abbreviated version of the Disabilities of the Arm, Shoulder and Hand [DASH]) questionnaires and visual analog scales for patient satisfaction. All treatments were performed by a single surgeon and all blinded follow-up measurements were made by a single physiotherapist. The participants were assessed at 1 week, 6 months, and 1 and 2 years after the interventions.

Results:
A total of 152 patients (97%) were examined at 2 years, at which time 58 patients (76%) treated with CCH and 60 (79%) treated with PNF retained a straight MCP joint. No cords were detectable in >50% of the patients at 2 years. There were no significant differences in the reduction of PIP contracture, range of motion, or patient-reported outcomes between the 2 treatments.

Conclusions:
This trial demonstrated no advantage of CCH treatment compared with PNF in terms of clinical outcome at any time during the 2-year follow-up. The significant decrease in the number of pathological cords (p < 0.0001, Wilcoxon signed-rank test) after disruption regardless of the method used may indicate that resorption of pathological collagen occurs when the tension in the Dupuytren cord is diminished.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
An Innovative Laboratory Method To Measure Pore-Pressure-Dependent Gas Permeability of Shale: Theory and Numerical Experiments
Authors: Liu Hui-Hai , Lai Bitao , Zhang Jilin , Huang Xinwo , Chen Huangye 
Published: July 2018

Summary
This work proposes an innovative laboratory method to measure shale gas permeability as a function of pore pressure, a key parameter for characterizing and modeling gas flow in a shale gas reservoir. The development is based on a solution to 1D gas flow under certain boundary and initial conditions. The details of the theoretical background, including formulations to estimate gas permeability and conceptual design of the test setup, are provided. The advantages of our approach, surpassing the currently available ones, include that it measures gas permeability (as a function of pressure) with a single test run and without any presumption regarding the form of parametric relationship between gas permeability and pore pressure. In addition, our approach allows for estimating both shale permeability and porosity at the same time from the related measurements. Numerical experiments are conducted to verify the feasibility of the proposed methodology.
Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells
Authors: Mabeta Peace , Pavić Kristina , Zorc Branka 
Published: July 2018

Abstract
In our previous paper, we showed that three primaquine-cinnamic acid conjugates composed of primaquine (PQ) residue and cinnamic acid derivatives (CADs) bound directly by an amide linkage (1) or through an acylsemicarbazide spacer (2 and 3) had significant growth inhibitory effects on some cancer cell lines. Compound 1 induced significant growth inhibition in the colorectal adenocarcinoma (SW620), human breast adenocarcinoma (MCF-7) and cervical carcinoma (HeLa) cell lines, while compounds 2 and 3 selectively inhibited the growth of MCF-7 cells. To better understand the underlying mechanisms of action of these PQ-CADs, morphological studies of the effects of test compounds on MCF-7 cells were undertaken using haematoxylin and eosin stain. Further analysis to determine the effects of test compounds on caspase activity and on the levels of apoptosis proteins were undertaken using the enzyme-linked immunosorbent assay (ELISA). Haematoxylin and eosin staining revealed that compounds 1 and 3 induced morphological changes in MCF-7 cells characteristic of apoptosis, while 2-treated cells were in interphase. Cell cycle analysis showed that cells treated with 1 and 3 were in sub-G1, while cells treated with 2 were mainly in interphase (G1 phase). Further, the study showed that the treatment of MCF-7 cells with 1 and 3 resulted in poly ADP ribose polymerase (PARP) cleavage as well as caspase-9 activation, indicating that they induced apoptotic cell death. We further investigated their effects on two important processes during metastasis, namely, migration and invasion. Compounds 1 and 3 inhibited the migration and invasion of MCF-7 cells, while compound 2 had a marginal effect.
Low molecular mass chondroitin sulfate suppresses chronic unpredictable mild stress-induced depression-like behavior in mice
Authors: Si Xiao-Ming , Tian Yu-Hua , Zhang Sha-Sha , Gao Hua , Liu Kun , Jin Jing-Yu 
Published: July 2018

Abstract
The present study is aimed at testing the antidepressant--like effects and probable mechanisms of action of low molecular mass chondroitin sulfate (LMMCS) on depression induced by chronic unpredictable mild stress (CUMS) in mice. Four weeks of CUMS exposure resulted in depressive-like behavior, expressed by a significant decrease in the locomotor activity and sucrose consumption and increased immobility time in the forced swim test. Further, there was a significant reduction of 5-HT level in the hippocampus region of depressed mice. Treatment of mice for four weeks with LMMCS ameliorated significantly both the behavioral and biochemical changes induced by CUMS. These novel results suggest that LMMCS produces an antidepressant-like effect in mice subjected to CUMS, which might be related, at least in part, to the increase of 5-HT concentration in the hippocampus.