bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reorienting Toward LGBTQ+ Belonging in Science, Technology, Engineering, and Mathematics by Feeling and Thinking With a Queer and Nonbinary Person in Virtual Reality
Authors: Paré Dylan 
Published: November 2024

ABSTRACTAs part of the special issue Centering Affect and Emotion Toward Justice and Dignity in Science Education, this paper analyzes participants' experiences playing an immersive virtual reality (VR) experience that explores gender and sexuality‐based marginalization in STEM fields. The VR experience, designed and developed by the author and collaborators, addresses cisheteronormative ideologies embedded in science education by reimagining traditional STEM objects in queer representational forms while engaging players in a branching narrative dialog about gender and sexuality‐based oppression. My findings include three in‐depth analyses of participants' moment‐to‐moment interactions while playing the VR application. I argue that extending queer phenomenological approaches in education through the complimentary combination of ideological stance‐taking and emotional configurations can highlight how people become reoriented toward solidarity with marginalized people in moment‐to‐moment interactions. I focus my analysis on how participants' emotions, elicited by the VR experience, became the pivot for their ideological reorientations in solidarity with the VR narrator. In particular, the VR stories and research excerpts I have shared give concrete examples of how LGBTQ+ people are harmed in STEM learning environments. The analysis reveals how participants made choices in the branching narrative that showed emotional configurations of care toward the marginalized VR narrator and demonstrated recognition of how sociopolitical/socioscientific systems fail LGBTQ+ people. Further, I argue how designing learning environments that reorient learners toward social justice and solidarity with marginalized people could be productively used to engage people in challenging dominant cisheteronormative framings embedded in STEM education.
Recent Advances in Nanomaterial‐Based Biosignal Sensors
Authors: Kim Minwoo , Hong Sangwoo , Khan Rizwan , Park Jung Jae , In Jung Bin , Ko Seung Hwan 
Published: November 2024

AbstractRecent research for medical fields, robotics, and wearable electronics aims to utilize biosignal sensors to gather bio‐originated information and generate new values such as evaluating user well‐being, predicting behavioral patterns, and supporting disease diagnosis and prevention. Notably, most biosignal sensors are designed for body placement to directly acquire signals, and the incorporation of nanomaterials such as metal‐based nanoparticles or nanowires, carbon‐based or polymer‐based nanomaterials—offering stretchability, high surface‐to‐volume ratio, and tunability for various properties—enhances their adaptability for such applications. This review categorizes nanomaterial‐based biosignal sensors into three types and analyzes them: 1) biophysical sensors that detect deformation such as folding, stretching, and even pulse, 2) bioelectric sensors that capture electric signal originating from human body such as heart and nerves, and 3) biochemical sensors that catch signals from bio‐originated fluids such as sweat, saliva and blood. Then, limitations and improvements to nanomaterial‐based biosignal sensors is depicted. Lastly, it is highlighted on deep learning‐based signal processing and human‐machine interface applications, which can enhance the potential of biosignal sensors. Through this paper, it is aim to provide an understanding of nanomaterial‐based biosignal sensors, outline the current state of the technology, discuss the challenges that be addressed, and suggest directions for development.
De Novo Design of Aminopropyl Quaternary Ammonium‐Functionalized Covalent Organic Frameworks for Enhanced Polybenzimidazole Anion Exchange Membranes
Authors: Chen Wanting , Liu Qiang , Pang Bo , Cui Fujun , Wang Leilei , Zhou Fengpu , He Gaohong , Wu Xuemei 
Published: November 2024

AbstractQuaternary ammonium functionalized covalent organic frameworks (COFs) have great potential to enhance hydroxide transport owing to crystalline ordered 1D nanochannels, however, suffer from limited quaternary ammonium functional monomers and poor membrane‐forming ability. In this work, a novel aminopropyl quaternary ammonium‐functionalized COF (DCOF) is designed and synthesized via a bottom‐up strategy. The self‐supporting DCOF membrane exhibits high crystallinity with a dense and orderly arrangement of quaternary ammonium groups (IEC, 2.07 mmol g−1), achieving a high hydroxide conductivity of 172.5 mS cm−1 and an extremely low water swelling of 5.3% at 80 °C. The exfoliated DCOF colloidal suspension is further incorporated into quaternary ammonium di‐cation grafted polybenzimidazoles (DPBI) matrix. Molecular simulations reveal strong electrostatic and van der Waals interfacial interactions between DCOF and DPBI, which enable a high doping content of 20 wt.% and interconnected ionic channels through the surface and nanochannels of the DCOF. The DCOF/DPBI‐20% membrane exhibits a tensile strength of 29.7 MPa, a hydroxide conductivity of 135.3 mS cm−1, and a low swelling ratio of 37.2% at 80 °C. A H2/O2 single cell assembled with the membrane reaches a peak power density of 323 mW cm−2, surpassing most recently reported COF‐based membranes.
Polyphenol‐Scaffolded Modular Assembly of Heterotypic Cell–Cell Assemblies for Potentiating Cancer Immunotherapy
Authors: Gong Guidong , Yin Qimin , Liu Qinling , Zhang Yajing , Liu Jinyuan , Dai Mengyuan , Li Jiawen , He Xianglian , Pan Jiezhou , He Yunxiang , Wang Bo , Tong Jiyu , Guo Junling 
Published: November 2024

AbstractCells existing in the form of clusters often exhibit distinct biological functions from their single‐cell counterparts. However, the ability to modulate cell–cell interactions among multiple cell types through molecular scaffolds remains an ongoing challenge. Here, a supramolecular phenolic network on surfaces of live cells designed is engineered to act as modular scaffolds that promote intercellular interactions, presenting a universal platform for the construction of cell–cell assemblies (CCAs). Utilizing the inherent cell surface affinity of supramolecular phenolic network modules, a series of heterotypic CCAs is efficiently established by assembling five distinct microorganisms and five types of mammalian cells. A specific application of CCAs with the combination of L. casei and macrophages (L. casei@Mφ) is highlighted for enhanced cancer immunotherapy. Upon intravenous administration, L. casei@Mφ allows the chemotactic Mφ to facilitate the accumulation of L. casei at the tumor. The accumulated L. casei enables the polarization of tumor‐associated Mφ toward a pro‐inflammatory phenotype, markedly improving the immunotherapeutic response, slowing tumor progression, and mitigating lung metastasis. This work demonstrates the potential of polyphenol‐scaffolded modular assembly in manipulating cell–cell interactions to enhance multicellular cooperation, offering a general approach to controlling complex cellular behaviors.
Solvent‐Free Ball Milling Synthesis of Water‐Stable Tin‐Based Pseudohalide Perovskites for Photocatalytic CO2 Reduction
Authors: Tsai I‐Hua , Huang Chun‐Wei , Chang Chun‐Fu , Diau Eric Wei‐Guang 
Published: November 2024

AbstractA pseudohalide (SCN−) tin‐based perovskite material using a solvent‐free ball milling method is developed. The synthesized perovskite exhibits long‐term water stability and demonstrated significant photocatalytic activity in reducing CO2 to CO under light irradiation. The structural transition from nanoparticles to planar perovskites is achieved by varying the ratios of dimethylammonium (DMA) and formamidinium (FA) cations, which is confirmed by X‐ray diffraction (XRD) and scanning electron microscopy (SEM) analyses. The surface elemental distribution, absorption spectra, band gap and energy levels estimations using energy‐dispersive X‐ray spectroscopy (EDS), Kubelka‐Munk function, and ultraviolet photoelectron spectroscopy (UPS) are thoroughly investigated. These findings indicated that the incorporation of DMA cations increased the band gap and shifted the absorption spectra toward the blue region. The optimal photocatalytic performance is observed for the perovskite composition with a 50% DMA cation ratio (DMA0.5FA0.5SnI(SCN)2), achieving a CO production yield of 285 µmol g−1 with 12 hours irradiation in humid environment. The efficiency is critically dependent on the ball milling speed and duration, with 400 rpm and 1 hour being the optimal conditions. This research highlights the potential of environmentally friendly synthesis methods in developing stable and efficient lead‐free perovskites as photocatalytic materials, contributing to the goal of net‐zero carbon emissions.
Verticality Bridging Multilayered MXenes by NCNTs for Rapid Electron/Ion Bi‐Continuous Transport
Authors: Zhang Yongshang , Huang Songyue , Lu Quanbing , Zhang Linsen , Du Lulu , Lau Kin‐tak , Zhang Peng 
Published: November 2024

AbstractEnlarging the interlayer structure of MXenes has been proven to be an effective strategy for enhancing the speed and efficiency of ion transport in assembled MXene‐based battery electrodes. However, the expanded interlayer space will inevitably lead to decreased interlayer conductivity because of the insufficient internal contact between isolated monolayered MXenes. Herein, the “rapid electron/ion bi‐continuous‐transport channels” are achieved by vertically growing N‐doped carbon nanotubes (NCNTs) into the interlamination to bridge multilayered MXenes. Importantly, both experimental and theoretical analyses demonstrate the co‐catalytic effect of Ni and MXenes on the growth of NCNTs, a phenomenon that has not been reported previously. The vertically grown NCNTs, serving as bridging pillars in the interlamination, not only significantly augment the interlayer structure but also forge a robust interconnection among the monolayered MXenes. Therefore, this design simultaneously realizes the enlargement of the interlayer space to facilitate electrolyte infiltration for fast ion transport and enhances the interlayer conductivity for rapid electron transport through the NCNTs bridging pillars. As a result, the as‐derived Ti3C2@NCNTs hybrids show a high reversible capacity of 610 mAh g−1 for Li+ storage and 158 mAh g−1 Na+ storage. This work provides a universal approach to regulating the properties of MXenes.
The introduction of surgical telementoring systems in rural hospitals
Authors: Tokunaga Takuya , Yoshikawa Masato , Shimada Mitsuo 
Published: November 2024

AbstractThe shortage of surgeons in rural hospitals is a serious problem in Japan. In this study, we investigated the potential contribution of surgical telementoring systems to improving surgical skills and resolving the shortage of surgeons in rural hospitals. The conference room at Tokushima University was connected to the operating room at Miyoshi Hospital, a rural hospital approximately 75 km away, via a virtual private network. Telementoring was conducted for surgeries performed at Miyoshi Hospital from Tokushima University using ADMENIC ANNOTATOR (Carina Corporation). A questionnaire using the NASA Task Load Index was completed by two surgeons who received remote instruction. The surgeries when using the surgical telementoring system had significantly better “mental”, “performance”, and “frustration” scores compared with those performed without using the system. In a questionnaire about the surgical telementoring system, both surgeons did not notice a communication delay and indicated that annotation and voice instruction was easier to understand than voice only. In addition, fifty fifth‐year medical students completed a questionnaire. After experiencing the surgical telementoring system, the number of students who responded favorably to working in a rural hospital increased from 22 (44%) to 31 (62%) (p < 0.01). Surprisingly, 10 of the 27 students who were not interested in becoming a surgeon indicated that they were now interested in becoming a surgeon (p < 0.01). This study suggests that the introduction of a surgical telementoring system in rural hospitals may help improve the skills of rural surgeons and contribute to eliminating the maldistribution and shortage of surgeons in the future.
Ovarian Cell Accumulation of Model PVC Nanoplastics Labelled With CdSe‐QDs Investigated by X‐Ray Fluorescence Microscopy
Authors: Gianoncelli Alessandra , Tufoni Cristina , Žižić Milan , Zingaro Federica , Ceccone Giacomo , Bonanni Valentina , Salomé Murielle , Villalobos‐Portillo Eduardo , Spina Rita La , Cassano Domenico , Ricci Giuseppe , Pascolo Lorella 
Published: November 2024

ABSTRACTThe distribution of micro‐ and nanoplastics (MNPs) in the environment is increasingly becoming a cause of concern for human health. The small size of these particles makes them prone to accumulate not only in the tissues of various organs but also enables them to enter cells and act as carriers of external materials and microbes. Since environmental pollutants influence both male and female reproductive function and foetal development, it is expected that this also applies to MNPs, as they can easily accumulate in reproductive organs. This highlights the potential risks associated with MNPs and the need for further research in this area. In the female reproductive system, the ovary plays a crucial role in producing oocytes. The SK‐OV‐3 human ovarian cancer cell line represents an epithelial‐like model for ovarian cells, and it has been widely used in nanomedicine and nanotoxicological studies. In the present study, x‐ray fluorescence (XRF) microscopy was used to investigate the accumulations of model polyvinyl chloride (PVC) nanoplastics (NPs), labelled with cadmium‐selenide quantum dots (CdSe‐QDs), in SK‐OV‐3 cells at sub‐micrometric spatial resolution. The Cd and Se QDs components distribution and the Cl of PVC were successfully used to track the NPs and to confirm that NPs do not leach the QDs, while endogenous elements such as Na, Mg, S and P were also monitored to investigate potential biochemical changes attributed to NPs toxicity. Our study suggests that nanoplastics made of PVC can accumulate in ovarian cells, even if they appear less incline than in other types of cells, such as macrophages. Moreover, our results demonstrate that XRF analyses are a useful tool for biological studies aimed at deepening our understanding on the toxicological mechanisms of pollutants on human fertility.
Tactile Travelling, Manual Space, and the Duality of Gothic Hands
Authors: Jacob Ramalho Joana 
Published: November 2024

AbstractThis chapter furthers the previous chapter’s exploration of dismemberment. It builds on Georges Braque’s notion of ‘manual space’ (Danchev, Georges Braque: A Life. London: Hamish Hamilton, 2005, 88) and Katherine Rowe’s ‘unexpected clutch’ and ‘mortmain control’ (1999) to examine the idea of independent agency and shifting discourses of power in the Gothic. This crystallises in an exploration of the image of the disembodied hand in La Belle et la Bête (Cocteau, 1946) and Wuthering Heights (Wyler, 1939), which present memory as disruptive and a threat to the sanity of the characters. Central here is an understanding of the hand as a locus of sublime terror, exile, and uncanny absence that challenges the integrity of the subject by violently emphasising its constructed nature and, consequently, its easy disassembly and destruction.
The State of Marriage in the Arab Maghreb: Tunisia, Algeria, Libya, Morocco, and Mauritania
Authors: El Harras Mokhtar , Saidani Mounir , Ait Mansour Hicham , Ould Hmeyada Mohamed 
Published: November 2024

AbstractExisting literature suggests that marriage in the Arab Maghreb region continues to be the prime institution governing the cohabitation of men and women, despite increasing rates of celibacy, permanent celibacy, and divorce, as well as a rise in critiques of the institution of marriage. And although various forms of marriage are emerging, or re-emerging under new circumstances, it is certain—to date—that the institution of marriage is perpetually and widely reproduced in the consciousness and practices of individuals. In the process, it fosters the close domestic and public connection between two families, regardless of the prevalence of individuality in society.
Cooperation of GlycoPOST and UniCarb-DR towards a comprehensive glycomics data repository workflow
Authors: Takahashi Yushi , Karlsson Niclas G. , Okuda Shujiro , Aoki-Kinoshita Kiyoko F. 
Published: November 2024

Abstract
In glycomics, two data repositories, GlycoPOST and UniCarb-DR, have been developed to accumulate experimental data generated by glycomics and glycoproteomics mass spectrometry experiments. In order to enhance the interrelation between these two data repositories, we have upgraded the framework for both of them; we have unified their respective data submission systems and constructed a mechanism that can automatically cross-reference corresponding entries. In addition to this integration, the metadata registration system was also extended so that liquid chromatography experiments can be reported according to standard reporting guidelines specified by MIRAGE (Minimum Information Required for A Glycomics Experiment). Furthermore, by augmenting the visualization software used in UniCarb-DR, we have been able to introduce new functionality into GlycoPOST to enable the visualization of unpublished experimental identification result files during an embargo period defined by the data provider. As a result, this work introduces a new framework by which glycomics researchers can take advantage of GlycoPOST and UniCarb-DR in an integrated manner.

Graphical abstract
Synergizing Ecotoxicology and Microbiome Data Is Key for Developing Global Indicators of Environmental Antimicrobial Resistance
Authors: Makumbi John P. , Leareng Samuel K. , Pierneef Rian E. , Makhalanyane Thulani P. 
Published: November 2024

AbstractThe One Health concept recognises the interconnectedness of humans, plants, animals and the environment. Recent research strongly supports the idea that the environment serves as a significant reservoir for antimicrobial resistance (AMR). However, the complexity of natural environments makes efforts at AMR public health risk assessment difficult. We lack sufficient data on key ecological parameters that influence AMR, as well as the primary proxies necessary for evaluating risks to human health. Developing environmental AMR ‘early warning systems’ requires models with well-defined parameters. This is necessary to support the implementation of clear and targeted interventions. In this review, we provide a comprehensive overview of the current tools used globally for environmental AMR human health risk assessment and the underlying knowledge gaps. We highlight the urgent need for standardised, cost-effective risk assessment frameworks that are adaptable across different environments and regions to enhance comparability and reliability. These frameworks must also account for previously understudied AMR sources, such as horticulture, and emerging threats like climate change. In addition, integrating traditional ecotoxicology with modern ‘omics’ approaches will be essential for developing more comprehensive risk models and informing targeted AMR mitigation strategies.
Bacteria-targeted imaging using vancomycin-based positron emission tomography tracers can distinguish infection from sterile inflammation
Authors: Spoelstra G. B. , Braams L. M. , IJpma F. F. A. , van Oosten M. , Feringa B. L. , Szymanski W. , Elsinga P. H. , van Dijl Jan Maarten 
Published: November 2024

Abstract
Introduction
Bacterial infections pose major challenges in medicine. To guide effective infection treatment, faster and more accurate diagnostic modalities are needed. Bacteria-targeted molecular imaging can meet these needs. The present study was aimed at the in vivo evaluation of two 18F-vancomycin-based PET tracers, for detection of deep-seated Gram-positive bacterial infections. These tracers were bench-marked against the current standard of care, [18F]FDG.

Methods
The potential of [18F]BODIPY-FL-vancomycin and [18F]PQ-VE1-vancomycin ([4+2]photocycloadduct of 9,10-phenanthrenequinone-vancomycin and [18F]fluorinated vinyl ether) to distinguish bacterial infections from sterile inflammation was evaluated in a murine myositis model. Tracer specificity was assessed by infecting mice either with the Gram-positive bacterium Staphylococcus aureus (n = 12) or the Gram-negative bacterium Escherichia coli (n = 12). The contralateral leg was injected with Cytodex beads to induce sterile inflammation, or with phosphate-buffered saline for control. In parallel, mice were imaged with [18F]FDG (n = 12). Dynamic positron emission tomography (PET) measurements, biodistribution analyses, and immunohistopathology were performed to determine tracer distribution and bacterial burden.

Results
Both 18F-vancomycin-PET tracers accumulated at sites of infection, but not at sites of sterile inflammation, in contrast to [18F]FDG. The tracers exhibited distinct biodistribution profiles, with [18F]BODIPY-FL-vancomycin being cleared more rapidly. Both 18F-vancomycin-PET tracers displayed significant target to non-target ratios of 2.95 for [18F]BODIPY-FL-vancomycin and 1.48 for [18F]PQ-VE1-vancomycin.

Conclusion
Vancomycin-based PET is a potentially attractive approach to distinguish Gram-positive bacterial infections from sterile inflammation.
Investigation of the coupling quality of partial prostheses at the stapes head
Authors: Zhai Sijia , Eßinger Till Moritz , Koch Martin , Deng Jianhang , Zahnert Thomas , Neudert Marcus , Bornitz Matthias 
Published: November 2024

Abstract
Introduction
The success of partial ossicular chain reconstructions in cases of conductive hearing loss depends on many factors. One important factor is the coupling between the prosthesis and the stapes head, which has not been explicitly investigated previously. Prostheses with different forms of attachment to the stapes are available, namely clip and bell type PORP. We present a standardized method to assess the quality of the prosthesis-stapes connection. The coupling quality of different prostheses is compared using measurements on a specimen model.

Methods
This study delineated six groups categorized by prosthesis types, employing 12 temporal bones to create a reconstructed ossicular chain model. The model comprised stapes and inner ear of the specimen, various prostheses and a standardized mechanical excitation at the prosthesis head. Multiple-points measurements were conducted using laser Doppler vibrometry along the sound transfer direction. This methodology enabled the assessment of vibrational magnitude loss and sound distortion from the prosthesis to the stapes.

Results
All six groups showed uniformly good sound transmission, with low magnitude loss of < 10 dB and very low total harmonic distortion of < 1%.

Conclusion
The proposed measurement method enables an explicit and comparable examination of the prosthesis coupling to the stapes head. While the coupling mechanism may be important in terms of handling, stability or long-term robustness of the reconstruction, our results show no relevant differences between types in terms of sound transmission.