bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interest Enhanced Subgraph Neural Network with Data Distillation Replay to Continual Learning for Session-based Recommendation
Authors: Liang Shunpan , Xi Hengchen , Yang Jixiang 
Published: December 2024

Abstract

Session-based recommendation (SBR) predicts potential items of interest by analyzing user behavior within sessions. In this work, we explore the continual learning for SBR task, a challenging and practical task closely aligned with real-world online recommendation system due to (1) periodic updates of the model may trigger catastrophic forgetting, and (2) the continuous emergence of new interactions reflects rapidly changing user interests. Although recent studies have mitigated catastrophic forgetting by replaying a small subset of historical data into the model, these samples fail to represent the distribution of the entire dataset. Moreover, the research on SBR when examining changes in user interests is confined to offline settings and does not adequately consider multiple time-correlated user interests. This limitation makes it challenging to finely model the rapid changes in user interests in continual learning. To overcome the limitations of traditional data replay, we propose a data distillation framework for SBR, which synthesizes information-rich samples for replay from the entire dataset instead of relying on simple sampling. Furthermore, to address the changing user interests in continual learning scenarios, we developed an Interest Enhanced Sub-graph Neural Network (IES-GNN), which is capable of efficiently extracting and dynamically modeling the evolution of user interests within sessions. Testing on three real-world datasets demonstrates that our approach outperforms several advanced methods in continual learning for SBR task.
Revised Estimates of Post-Net Zero CO2 Temperature Changes
Authors: Borowiak Alex , King Andrew , Brown Josephine , Ziehn Tilo 
Published: December 2024

Abstract

It is critical that climate changes beyond net zero are well understood to inform policymaking. Here we present a new estimate of post-abrupt net zero CO2 changes using a method that filters for decadal variability. Our findings indicate that 50 years after abrupt emission cessation, the multi-model median temperature change is -0.18˚C, with a range spanning from − 0.44˚C to 0.04˚C, which is substantially cooler than previous estimates.
Islanding Detection of a Grid-Connected DFIG - Based Wind Generator Using Fuzzy-Estimator Based Active Power Perturbation
Authors: Manna Pranendu , Nandi Sharmistha , Das Tanaya Datta , Bajpai Prabodh 
Published: December 2024

Abstract

Unintentional islanding may occur at any instance of time due to some faults or some anonymous problem in the system. It is a big problem for power system security, which can damage the equipment and also can be very dangerous for the maintenance workers. Therefore, fast detection of islanding is essential. In this paper, a Hybrid Islanding Detection Relay (IDR) employing a scaled active power perturbation along with classical ROCOF based detection has been introduced. Active disturbance serves as an identifying factor in detection of an island. But keeping in mind the issue with the power quality, in this paper, it is administrated only on detecting a case of disturbance. A fuzzy estimator predicts the natural peak value of the ROCOF on detecting a disturbance. The magnitude of active power perturbation to be administered is scaled using this estimate such that it is introduced only in cases which fall in the Non-Detection Zone (NDZ) of the classical ROCOF based IDR. The results presented in the study illustrate the effectiveness of the proposed islanding detection scheme.
Comparative Analysis of 8x8 MIMO-OFDMA and NOMA Systems
Authors: GSSSIETW RAGHAVENDRA , M Asha , G Manjula , m Latha , Sindgi Anupama , R Amrutha 
Published: December 2024

Abstract

This paper presents a comprehensive performance analysis of an 8x8 MIMO (Multiple Input Multiple Output) system using Orthogonal Frequency Division Multiple Access (OFDMA) and Non-Orthogonal Multiple Access (NOMA) techniques. The study is conducted at a carrier frequency of 1 GHz, utilizing 16-QAM modulation, an FFT size of 512, a cyclic prefix of 64 samples, and a Signal-to-Noise Ratio (SNR) range from-10 to 20 dB. Key performance metrics, including Bit Error Rate (BER), Error Vector Magnitude (EVM), and channel gain diversity, are evaluated across both multiple access schemes. Simulation results reveal the strengths and weaknesses of OFDMA and NOMA under identical conditions, highlighting how each technique impacts BER performance, EVM behaviour, and SNR gain per receive antenna. The results indicate that OFDMA consistently achieves lower BER, with a value of approximately 0.43 at 20 dB SNR, compared to NOMA's 0.86, showcasing its superior reliability in high SNR conditions. EVM results also favor OFDMA, achieving 15 dB lower EVM at 20 dB SNR, indicating better signal quality. However, NOMA demonstrates higher spectral efficiency and improved fairness between users, making it advantageous in resource-constrained scenarios. Overall, OFDMA is recommended for applications prioritizing low BER and high signal quality, while NOMA is more suitable for systems aiming to maximize user capacity and spectral efficiency.
Single cell landscape of sex differences in the progression of multiple sclerosis
Authors: Irene Soler-Sáez , Borja Gómez-Cabañes , Rubén Grillo-Risco , Cristina Galiana-Roselló , Lucas Barea-Moya , Héctor Carceller , María de la Iglesia-Vayá , Sara Gil-Perotin , Vanja Tepavčević , R. Hidalgo Marta , Francisco García-García 
Published: December 2024

Abstract

Background
One of the major challenges in addressing multiple sclerosis is to understand its progression trajectory. The pathological process transitions from acute phases predominantly driven by inflammation to progressive clinical profiles where neurodegeneration takes precedence. The factors mediating this heterogeneity remain unresolved. However, it is known that sex plays a crucial role; females are two to three times more likely to suffer from multiple sclerosis, while males suffer from more rapid neurodegeneration with greater severity.
Results
We profiled 48,919 central nervous system and 336,934 peripheral immune cells, covering the multiple sclerosis spectrum. We generated cell-type specific landscapes, including gene signatures from differentially expressed genes, functional profiling, pathway activation, and cell-cell communication networks for females, males, and their sex differential profiles. Among our findings, we revealed that female neurons may exhibit protective mechanisms against neurodegeneration. In the inflammatory-predominant forms, female immune cells present an inflammatory core driven by the AP-1 transcription factor, while male adaptive immune cells exhibit higher mitochondrial impairment. Conversely, larger differences are reported in CD8 + T cells progressive forms, with males exhibiting cytolytic profiles that may promote neurodegeneration. Complete results can be explored in the user-friendly interactive webtool https://bioinfo.cipf.es/cbl-atlas-ms/.
Conclusions
We identified cell-type specific sex differences in brain and immune cells that vary in the spectrum of multiple sclerosis progression. We consider this molecular description of sex differences to be valuable resources to promote future targeted approaches to specific molecular mechanisms considering the sex of the individual.
Myelosuppression in a Metastatic Breast Cancer Patient with GSTP1 rs1695 Mutation Induced by Adriamycin and Cyclophosphamide
Authors: S Arun , Kumar Pramod , M Megha , Saravanan Aswini , Nair Rishi P , Singh Surjit , Ambwani Sneha 
Published: December 2024

Abstract

Introduction: Adriamycin and cyclophosphamide (AC) combination chemotherapy is one of the common regimens used for breast cancer and in metastatic breast cancer with oligo-metastasis. (1) AC combination chemotherapy regimen is associated with adverse drug reactions like myelosuppression, gastrointestinal toxicity, cardiotoxicity, peripheral neuropathy, and hand-foot syndrome. (2),(3),(4) It has been noticed from previous studies that the metabolism-related gene GSTP rs 1695 homozygous mutant allele has been associated with higher incidences of myelotoxicity and gastrointestinal toxicity post-combination chemotherapy regimens. (5)
Case report: A 55-year-old female patient presented with the incidence of grade 3 febrile neutropenia and myelosuppression, 8 days following AC infusion. The patient also has symptoms of grade 2 peripheral neuropathy and diarrhea. She was treated as an inpatient from the local hospital with pegfilgrastim, packed RBC transfusion, and intravenous antibiotics for febrile neutropenia. She recovered completely with this treatment and was discharged without any sequelae or complications. She was then tested for the GSTP rs 1695 gene which revealed the homozygous mutant variant (GG allele).When reporting the causal association of the adverse drug reaction, it comes under the “possible” category of WHO causality assessment.
Conclusion: Myelosuppression, Diarrhea, and other adverse events following AC combination chemotherapy can be related to the Genetic polymorphism in GSTP rs 1695 double mutant homozygous allele (GG ) and its altered drug metabolism effects. The Adverse drug reaction comes under the “Possible”Category of WHO causality assessment.
Ich bin begehrt oder: Auch digitale Trennungen sind kompliziert
Authors: Lutz Klaus 
Published: December 2024

Ich bin kein Mensch, der sich in seinem Leben häufig getrennt hat. Zum Abzählen der Beziehungstrennungen reicht eine Hand locker aus – da sind aber auch schon die Liebschaften im Kindergarten mitgezählt. Das Land habe ich ebenfalls nicht gewechselt, sondern bin nur von Unterfranken nach Mittelfranken umgezogen und dann noch von Nürnberg nach Fürth. Auch meine beruflichen Beziehungen sind äußerst stabil. Seit über 35 Jahre arbeite ich jetzt schon für denselben Arbeitgeber.
Die neue digitale Welt zwingt mich aber dazu, verschiedene Beziehungen zu Dienstleistern einzugehen, die von nicht allzu langer Dauer sind. ‚Beziehungs-Hopping‘ ist da das Gebot der Stunde. Allein um meine Fußballleidenschaft digital vor dem heimischen TV-Gerät ausleben zu können, bedarf es eines ausgeklügelten Beziehungsmanagements zwischen Sky und DAZN: Mal bändle ich mit dem einen Sender an (wenn es um die Spieltage am Samstag und Sonntag geht), mal muss ich mich (für Freitags- und Sonntagsspiele) wieder kurzfristig dem anderen Anbieter zuwenden und ihm ewige Treue schwören – die ich natürlich nicht einhalte. Denn kaum ist der Vertrag geschlossen, kündige ich zur Vermeidung von Abofallen gleich wieder. Aber wer gedacht hat, digitale Dienstleister hätten keine Gefühle, irrt sich. Folgende Mail erreicht mich bald nach der Kündigung von Sky: „Hallo Klaus, komm zurück!“. DAZN setzt nach mit: „Was können wir tun, damit du bei uns bleibst?“. Netflix und Sky Serie – mit denen ich mich aufgrund der Neuauflage von ‚Der Doktor und das liebe Vieh‘ auf ein kurzes Techtelmechtel eingelassen hatte – lassen ebenfalls nicht locker. Auch sie versuchen, die drohende Trennung abzuwenden, indem sie mich mit Nachrichten drangsalieren, wie „Willst du uns wirklich verlassen?“ und „Das könnte doch auch interessant für dich sein!“.
Kaum hatte ich mich an diese Art von Beziehungsterror gewöhnt, zündete meine langjährige Telefonpartnerin Vodafone – von der ich mich nach 20 Jahren zu trennen versuche – eine neue Stufe. Sie belässt es nicht bei Mails, sondern reagiert auch ganz altmodisch: Sie ruft mich an! Mindestens einmal in der Woche erhalte ich seit längerem einen Anruf von einer Dame, die von mir die Gründe meiner Trennung wissen möchte und besorgt nachfragt, ob es nicht doch einen Weg gäbe, mich umzustimmen. Kurz habe ich mir überlegt, woher die eigentlich meine Telefonnummer haben, bis mir einfiel, dass die sowieso alles über mich wissen. Die Gespräche werden inzwischen immer unfreundlicher und ich bin dazu übergegangen, die Nummer einfach wegzudrücken. Wie im richtigen Leben. Ich hoffe nur, dass meine enttäuschte Telefonanbieterliebschaft nicht bald einen Schlägertrupp schickt, der mir handfest die Gründe für einen Verbleib erklären soll.

Ansonsten überlege ich – nachdem ich pandemiebedingt viele Freizeitaktivitäten reduzieren oder einstellen musste – ganz ernsthaft, ob ich nicht vielleicht das Abschließen und Kündigen von digitalen Beziehungen zu meinem Hobby machen soll. Irgendwie hat man da das gute Gefühl, unglaublich begehrt zu sein.
ИСТОРИЯ И ТЕОРИЯ: “RETURN TO THE REAL
Authors: И.М. Савельева 
Published: December 2024

Теория исторической науки претерпевает сегодня очередную трансформацию. На смену завершившемуся лингвистическому и культурному поворотам идет новая парадигма, которую с необходимой осторожностью можно назвать «возвращением к реальному». Происходящая смена эпистемологических ориентиров отличается беспрецедентным интересом историков к проблемам исторического времени, причем она позволяет говорить о радикально новом видении не только исторического времени, но и исторического пространства. В первой части данной статьи представлены некоторые направления радикальных новаций в теории истории, наметившиеся буквально в последние годы, вторая часть содержит анализ новых подходов к историческому времени.
The theory of history is again undergoing yet another transformation. Linguistic and cultural turns have occurred and have been completed. A new paradigm which, with certain precaution, could have been named “back to reality” is on its way. The ongoing metamorphose of epistemological foundations is characterized by unprecedented interest of historians to the problems of historical time. At the same time, this change allows a discussion not only about considerably new vision of historical time but also that of historical space. In the first part of this article we discuss several indicators of radical innovations in the theoretical history which occurred just in the past few years. In the second part we analyze new approaches to historical time.
ПОКАЗАТЕЛЬНЫЕ ДЕМОНСТРАЦИИДЛЯ ПОКАЗАТЕЛЬНОГО ПРОЦЕССА«ДЕЛО “ПРОМПАРТИИ”»
Authors: А.И. Маслова 
Published: December 2024

Статья посвящена реконструкции одной из крупнейших советских демонстраций 1930 г., проходившей в рамках кампании, связанной с проведением показательного суда над советскими инженерами, известного как «дело “Промпартии”». На основе профсоюзной документации в статье анализируется динамика проведения демонстрации и предшествующих ей митингов. Демонстрация рассматривается как форма взаимодействия формирующегося сталинского режима со своей социальной базой (одновременно же и референтной группой) – рабочей средой.
The article reconstructs one of the greatest Soviet mass demonstrations of the 1930s linked to the campaign, which was organized in connection to the show trial of Soviet engineers, the so-called case of the “Industrial Party”. The trade union records show the dynamics of the mass demonstration and of the meetings that had preceded it. Demonstration is seen here as a form, by which the emerging Stalin’s regime interacted with its social base (and reference group) – the labourers.
«ТРЕТЬЯ ВОЛНА» MEMORY STUDIESКУЛЬТУРНАЯ ПАМЯТЬ МЕЖДУ ОПЫТОМ И РЕПРЕЗЕНТАЦИЕЙ
Authors: Ф.В. Николай 
Published: December 2024

Статья посвящена современным исследованиям культурных практик коммеморации. Рассматриваются эффекты роста новых медиумов (фотографии, видео, интернет-коммуникаций) и их влияние на историческое знание. Проблематизируется тезис о складывании «третьей волны» memory studies, уравнивающей в правах жизненный опыт и медиа-репрезентации за счет гибкого сочетания историографического анализа и аффективной вовлеченности в культурные практики. Культурная память сегодня все чаще понимается как перформативный процесс, затрагивающий одновременно индивидуальную и групповую идентичность, что существен-но меняет представление историков о своей дисциплине и активизирует их диалог с memory studies. Этот диалог обладает внутренней логикой, однако не исключает «силовых полей» напряжения и нестыковки аналитических позиций. Поэтому тезис о формировании единого пространства «исторической коммеморации» представляется спорным, так как скорее нивелирует важные различия между историей и памятью, чем стремится их проработать.
The article is devoted to contemporary studies of cultural commemoration practices. The effects of new mediums (photos, video, Internet communications) and their influence on historical knowledge are considered. Thesis about the "third wave" of memory studies, equalizing the rights of life experience and media representation through a flexible combination of rational analysis and affective involvement in cultural practices, is being questioned. Cultural memory today is increasingly understood as a performative process that affects both individual and group identity. This point of view significantly changes historian’s ideas about their discipline and activates their dialogue with memory studies. This dialogue has internal logic, but does not exclude "force fields" of tension and inconsistencies in analytical positions. Therefore, thesis of forming a single space of "historical commemoration" seems controversial, since it rather neutralizes important differences between history and memory, rather than strives to working-through them.
An Association between Bilirubin and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus: An Effect Modification by Nrf2 Polymorphisms
Authors: Fan Qiwei , Feng Shanshan , Chen Jianrong , Zhang Yan , Xu Jixiong , Wang Jiancheng 
Published: December 2024

Background:
Diabetic retinopathy (DR) is a persistent microvascular complication associated
with diabetes, and it constitutes a significant cause of visual impairment and blindness.

Aims:
This study aimed to assess the correlation between serum bilirubin levels and the prevalence
of DR in patients diagnosed with type 2 diabetes mellitus (T2DM). Additionally, we sought
to establish whether the polymorphisms of Nuclear Factor E2-Related Factor 2 (Nrf2) might modify
this relationship.

Methods:
A cross-sectional study was undertaken in Jiangxi, China, from May, 2012 to December,
2014. Serum bilirubin levels were assessed in 558 subjects, and the correlation between bilirubin
and DR was analyzed using generalized linear models with a logit link. The study utilized
odds ratios (OR) and 95% confidence intervals (CI) to evaluate the relationship, both with and
without the consideration of clinical risk factors.

Results:
There was a significant inverse association between serum total bilirubin (TBiL) and the
risk of DR (per 1-μmol/L increment; OR, 0.89; 95% CI: 0.84-0.94). Accordingly, when TBiL was
categorized into tertiles, individuals in tertiles 2 and 3 exhibited significantly lower risks of DR
compared to those in tertile 1. The OR for these tertiles was 0.54 (95% CI: 0.34-0.87) and 0.31
(95% CI: 0.19-0.52), respectively. Moreover, a stronger inverse relationship between TBiL and
DR was observed in individuals carrying the CC and AC genotypes compared to those with the
AA genotype. The OR for individuals with the CC/AC genotype was 0.87 (95% CI: 0.82, 0.92),
while that for the AA genotype was 1.17 (95% CI: 0.95, 1.45). This difference was statistically significant
(p for interaction = 0.001).

Conclusion:
There was a significant inverse association between bilirubin and DR in participants
with CC or AC genotype. However, this inverse association was not seen in AA genotype participants.
Review of Patents on Small Grinding Wheel Polishing Technology
Authors: Li Guo , Zhu Kuntan 
Published: December 2024

Abstract:
Grinding disc polishing is an important polishing method that can be used to manufacture
various high-precision and high-quality optical components. The smoothing effect of grinding
discs is a simple and effective method widely used to suppress MSF errors. Grinding disc technology
has good polishing effects on flat, spherical, aspherical, and free form surfaces. The polishing
mechanism is to generate chips through the small plastic cutting of abrasive particles, but it only
uses a very small amount of abrasive particles to exert force and uses the flow friction between the
abrasive particles and the grinding disc and the workpiece to flatten the surface roughness of the
workpiece. It can be seen from the relevant literature that the floating tool holder maintains a constant
pressure to solve the problem of uneven pressure distribution between optical components.
The adjustable tool holder can adjust the amount of spring deformation to adapt to local surface
changes of optical parts, ensuring consistent material removal. The force-adaptive tool holder can
be adjusted in real time during the machining process to reduce errors generated during machining.
The jointed tool holder improves the fit between the grinding wheel and optical components,
ensuring a tight fit between the grinding wheel and optical components.
This patent paper aims to introduce grinding wheel polishing technology as an essential method
for manufacturing high-precision, high-quality optical components. It explores the optimization of
abrasive tool design and the improvement of processing efficiency and proposes suggestions and
prospects for future research, applications, and development.
Through querying literature and patent databases, patent documents related to grinding disc polishing
technology were collected and analyzed. The design characteristics of the device structure,
technological innovations, as well as the effectiveness and improvements in practical applications
were focused.
Grinding disc polishing technology effectively removes surface defects and enhances the optical
performance of optical components, particularly in suppressing MSF errors. This technology is
suitable for flat, spherical, non-spherical, and freeform surfaces, with broad potential applications.
Despite the numerous advantages of grinding disc polishing technology, such as simplicity, effectiveness,
and wide applicability, critical issues still need to be addressed, including surface morphology
control, improving polishing efficiency, and enhancing consistency. Future research
should focus on optimizing tool design and developing new polishing materials and processes to
improve the manufacturing quality and efficiency of optical components.