bluuebunny/crossref_metadata_2025_split huggingface dataset:
O estatuto da metrópole e os desafios do planejamento da região metropolitana
Authors: Toledo Caíque , Pereira dos Santos Ademir , Fernando Morelli Ademir 
Published: December 2024

O presente artigo aborda a implementação da Lei Federal nº 13.089 de 12 de janeiro de 2015, denominado como Estatuto da Metrópole, que visa promover a elaboração de políticas públicas para Regiões Metropolitanas (RM) no Brasil, com o objetivo de analisar, especialmente, os desafios enfrentados pela elaboração do Plano de Desenvolvimento Urbano Integrado (PDUI) que consolidaria de fato a Região Metropolitana do Vale do Paraíba e Litoral Norte (RMVPLN), criada em 2012, portanto, há 14 anos, sem cumprir a obrigatoriedade prevista na legislação federal e estadual. A metodologia empregada para sua produção inclui revisão bibliográfica e análise documental de legislações e planos regionais. Os resultados indicam que, apesar do prazo estabelecido, a maioria das Regiões Metropolitanas, incluindo o Vale do Paraíba e o Litoral Norte, ainda não conseguiu elaborar o PDUI, o que compromete a gestão integrada e o atendimento das demandas da população. Conclui-se que a falta do planejamento concreto e de ações efetivas e conjuntas entre os municípios continua sendo um obstáculo para o desenvolvimento sustentável e equitativo das regiões metropolitanas, e particularmente da RMVPLN.
A governança corporativa
Authors: Paiva de Medeiros Marcia , Fogaça Rodrigues Maricato Andreia , Aparecida de Araujo Querido Oliveira Edson 
Published: December 2024

O objetivo do presente estudo foi analisar a existência (ou não) de Governança Corporativa no Terceiro Setor do Município de Caraguatatuba, em face das mudanças da legislação, especialmente com a aprovação da Lei Federal n. 13019/14 (Marco Regulatório do Terceiro Setor). Tomando como base o citado Marco Regulatório e a premissa de que as estruturas de governança corporativa são (ou podem ser) aplicadas ao terceiro setor, sendo mais assertivas quando atreladas à sua gestão, no que tange à promoção de transparência, responsabilidade, prestação de contas e sustentabilidade, esse estudo histórico e jurídico, com pesquisa exploratória, documental e bibliográfica, com base em documentos oficiais, relatórios de prestação de contas e dados obtidos no site do município, além de estudo de caso com respostas em formulário específico, possibilitou uma investigação e apresentação de resultados. O texto destaca que, apesar das OSCs de Caraguatatuba apresentarem mudanças em relação à presença dos princípios da Governança Corporativa em sua gestão após a aprovação da Lei, e demonstrar potencial para colaborar eficientemente com o setor público, ainda há necessidade de aprimoramento, especialmente em relação à transparência, liderança descentralizada, avaliação objetiva de desempenho e conformidade legal, ressaltando a importância da implementação do Marco Regulatório para melhorar a fiscalização, monitoramento e prestação de contas. O estudo também traz a relação entre as parcerias realizadas e o cumprimento dos ODS – Objetivos de Desenvolvimento Sustentável da Agenda 2030, metas 17.17 e 17.8.
A IMPORTÂNCIA DO COMBATE AO FEMINICÍDIO RACIAL EM MULHERES NEGRAS.
Authors: Lima Isabelly Menezes , Lima Tatiana de Oliveira , Simão Francisco Tacio de Souza , Oliveira Adriano Dos Santos 
Published: December 2024

O feminicídio, definido como o assassinato de mulheres devido ao gênero, é uma forma extrema de violência que afeta desproporcionalmente mulheres negras no Brasil. Esse fenômeno revela a interseção entre racismo e violência de gênero. Embora as taxas de homicídios femininos para mulheres brancas tenham diminuído, as mulheres negras continuam a sofrer desproporcionalmente, evidenciando as desigualdades raciais persistentes no país. Este trabalho tem como objetivo geral analisar essa interseção entre racismo e violência de gênero, com foco no assassinato de mulheres negras, utilizando uma metodologia de revisão de literatura. A criação de uma cultura de respeito e igualdade, que garanta a segurança e dignidade para todas as mulheres, independentemente de raça, requer campanhas educativas e programas de formação. Além disso, a incorporação das demandas dos movimentos sociais nas políticas públicas é crucial para promover justiça e combater esse tipo de violência. Um compromisso coletivo e uma abordagem interseccional são necessários para construir uma sociedade onde todas as mulheres possam viver sem medo e com dignidade.
القياس على الأكثر عند نحاة العربية وما يترتب عليه
Authors: الحاج صالح عبد الرحمن 
Published: December 2024

يُكثر كلّ النّحاة العرب من القول بأنّ " الأكثر هو الّذي يقاس عليه" ولا يُقاس على الأقل. قال سيبويه: "لأنّ فُعالا في الأسماء إذا جاوز الأفعلة إنّما يجيء عامّته على فِعْلان، فعليه تقيس على الأكثر" (1/101). وقال:" هو أظرف الفتيان وأجمله ليس بمطّرد ولا يُقاس عليه" (1/41). وقال أيضا: "ولكن الأكثر يُقاس عليه" (2/216). وقال: فهذا الأقل نوادر تحفظ عن العرب ولا يقاس عليه(2/215)، فماذا يريد سيبويه- ومن جاء بعده من النّحاة- مِن هذا الّذي يسميه " الأكثر" ولماذا يجب أن يُقاس عليه لا على الأقلّ قد يكون كثيرا فيما سمع من العرب؟
إنّ كلّ من جاء بعد سيبويه من النّحاة في العصور الأولى قد أدركوا جيّدا ما كان يقصده من ذلك. وأوّل من حاول توضيح "القياس على الأكثر" مع الحفظ للأقل الّذي قد لا يكون غيره فيما سمع من العرب، هو أبو بكر بن السّرّاج (في كتاب الأصول في النّحو (1/57)) وتبعه في ذلك تلميذه أبو عليّ الفارسي، وأفاض في هذا الموضوع بعدهما ابن جنّي.
Kajian Etis Teologis Terhadap Remaja yang Melakukan Pernikahan Dini
Authors: Lumi Altje , Kawengian Elsadai Sofiana 
Published: December 2024

Penelitian ini bertujuan untuk memberikan pemahaman yang lebih luas mengenai pernikahan yang merupakan pemberian Allah sehingga fenomena pernikahan dini di kalangan remaja dapat dihindari. Perlu diketahui bahwa anak remaja adalah masa-masa mereka beranjak dari kanak-kanak ke dewasa sehingga diperlukan juga bimbingan dari orang Tua, karena orang tualah yang menjadi guru dalam kehidupan seorang anak sehingga dia bisa memahami mana yang seharusnya dilakukan. Penulis menggunakan penelitian dan pendekatan kualitatif agar menghasilkan data berupa kata-kata tertulis atau lisan dari orang- orang dan perilaku yang dapat diamati. Dalam mengumpulkan data, penulis juga melakukan teknik wawancara dengan pertanyaan yang telah disusun agar mendapatkan pendapat tersendiri dari para responden. Penulis mengadakan observasi, untuk mengamati hal-hal yang penting yang berhubungan dengan pokok penelitian atau pengamatan tentang keadaan-keadaan yang terjadi di lokasi penelitian.
Dampak Dana Spontan Terhadap Persekutuan Ibadah di Jemaat GMIM Eben Haezer Pahaleten Wilayah Kakas Satu
Authors: Maindoka Brela Agnesia , Sarimbangun Ramli 
Published: December 2024

Artikel ini bertujuan untuk melakukan analisis secara mendalam mengenai dampak dana spontan terhadap persekutuan ibadah di Jemaat GMIM Eben Haezer Pahaleten Wilayah Kakas Satu. Masalah yang timbul berkaitan dengan dana spontan ini, di mana pengambilannya sudah tidak seperti awal pembentukannya sehingga membuat jemaat merasa risih akan adanya perilaku ini. Metode penelitian yang digunakan untuk memecahkan persoalan tersebut adalah metode penelitian kualitatif dengan tahapan pengumpulan eksplorasi kepustakaan yang teruji secara ilmiah seperti buku dan jurnal, tanpa mengabaikan data lapangan. jika pelaksanaan dana spontan ini dilakukan dengan cara yang baik maka akan memiliki dampak yang baik, sebaliknya jika diambil dengan cara yang kurang tepat maka akan menimbulkan dampak yang tidak baik. Tulisan ini diakhiri dengan kesimpulan yang berisi tentang tercapainya tujuan penelitian.
Att ändra arbetssätt och kultur inom den inledande aritmetikundervisningen
Authors: Neuman Dagmar 
Published: December 2024

Utgående från den holistiska kunskapssyn som representerar fenomenologin och den fenomenografiska forskningsansatsen diskuterar jag i den här artikeln observationer redovisade i min nu drygt tjugosex år gamla avhandling, i boken Räknefärdighetens rötter samt i en senare studie av hur barn dividerar. Observationerna gäller dels elever som deltar i specialundervisning i matematik i grundskolan, samt elever i gymnasieskolan som anser sig lida av matematiksvårigheter 1, och dels skolnybörjare som ännu inte har undervisats i matematik. De visar
– att det som främst tycks förorsaka grava eller specifika matematiksvårigheter är att eleverna saknar talföreställningar samt förståelse för sambandet mellan de fyra räknesätten
– att sådana begrepp och föreställningar knappast utvecklas genom skolans tabellträning
– attmångabarnintuitivtbörjarutvecklatalföreställningarföreskolstarten,samtidigt med att de formar konkreta representationer som blir till abstrakta föreställningar om tal.
Avslutningsvis ställer jag frågan: skulle den stora andel elever som nu lämnar grundskolan utan godkänt betyg i matematik möjligen kunna reduceras genom ett paradigmskifte inom den kultur som styr hur den grundläggande aritmetiken behandlas under de första skolåren?
Association of Sjögren's Syndrome With Reduced Lifetime Sex Hormone Exposure: A Case–Control Study
Authors: McCoy Sara S. , Sampene Emmanuel , Baer Alan N. 
Published: June 2019

ObjectiveTo test whether cumulative estrogen exposure, as determined by age at menarche, age at menopause, female hormone use, hysterectomy, and parity, have an effect on the development of primary Sjögren's syndrome (SS).MethodsWe performed a case–control study of 2,680 women from the Sjögren's International Collaborative Clinical Alliance registry, including 1,320 registrants with primary SS and 1,360 with sicca symptoms but no key features of primary SS (sicca controls). The composite estrogen score (CES) was calculated by point assignment for early menarche (age ≤10 years), high parity (>3 pregnancies), hysterectomy, female hormone use, and late menopause (age ≥53 years). Cumulative menstrual cycling (CMC) was calculated as years menstruating minus time pregnant.ResultsUsing a regression model that adjusted for age, recruitment site, ethnicity, education, employment status, and smoking, we observed a progressive inverse trend between primary SS and CES. The odds ratio (OR) and 95% confidence interval (95% CI) were as follows for the sicca control group: CES 1, OR 0.81 (95% CI 0.67–0.99); CES 2, OR 0.74 (95% CI 0.57–0.97); CES 3, OR 0.50 (95% CI 0.30–0.86). This trend was corroborated by analysis of CMC. At the highest level of CMC within the postmenopausal group there was a 24% reduction in cumulative sex hormone exposure among primary SS participants relative to controls.ConclusionWomen with primary SS have lower estrogen exposure and CMC compared to sicca controls. Increasing estrogen exposure was negatively associated with development of primary SS. Further longitudinal studies of sex hormone exposure in primary SS are needed to confirm these findings.
An adaptive learning and control architecture for mitigating sensor and actuator attacks in connected autonomous vehicle platoons
Authors: Jin Xu , Haddad Wassim M. , Jiang Zhong‐Ping , Kanellopoulos Aris , Vamvoudakis Kyriakos G. 
Published: June 2019

SummaryIn this paper, we develop an adaptive control algorithm for addressing security for a class of networked vehicles that comprise a formation of
human‐driven vehicles sharing kinematic data and an autonomous vehicle in the aft of the vehicle formation receiving data from the preceding vehicles through wireless vehicle‐to‐vehicle communication devices. Specifically, we develop an adaptive controller for mitigating time‐invariant state‐dependent adversarial sensor and actuator attacks while guaranteeing uniform ultimate boundedness of the closed‐loop networked system. Furthermore, an adaptive learning framework is presented for identifying the state space model parameters based on input‐output data. This learning technique utilizes previously stored data as well as current data to identify the system parameters using a relaxed persistence of excitation condition. The effectiveness of the proposed approach is demonstrated by an illustrative numerical example involving a platoon of connected vehicles.
Predictive value of computed tomography in the recurrence of chronic rhinosinusitis with nasal polyps
Authors: Meng Yifan , Zhang Luo , Lou Hongfei , Wang Chengshuo 
Published: June 2019

BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is a nasal disease with a high tendency for recurrence. The aim of this study was to compare the use of computed tomography (CT) scan with other clinical parameters in predicting the recurrence of CRSwNP.MethodsA total of 272 consecutive CRSwNP patients undergoing endoscopic functional sinus surgery were recruited. The demographic characteristics and clinical parameters, including CT scores, level of exhaled nitric oxide, and peripheral eosinophilia, were recorded. The degree of infiltration of inflammatory cells in the sinus mucosa was evaluated.ResultsTwo hundred thirty of the 272 patients completed the study (118 patients with recurrence and 112 patients with no recurrence). The average follow‐up time was 24 months after the first surgery. The 2 groups were not significantly different with respect to age, gender distribution, comorbid allergy, exhaled oral fractional exhaled nitric oxide levels, nasal obstruction/runny nose/headache/facial pain scores, Lund‐Mackay score, peripheral eosinophil percentage, and peripheral eosinophil absolute count. The onset of surgical history and asthma, visual analog scores of CRS, anosmia score, ratio of total ethmoid sinus scores for both sides and maxillary sinus score for both sides (E/M ratio), Lund‐Kennedy score, tissue eosinophil percentage, and tissue eosinophil absolute count were significantly higher in the recurrence group. The E/M ratio showed high accuracy as a predictor for CRSwNP recurrence. The cut‐off point of 2.55 for E/M ratio indicated the highest predictive value of CRSwNP recurrence.ConclusionThe E/M ratio is a useful predictor for the recurrence of CRSwNP in the Chinese population.
A Nanozyme with Photo‐Enhanced Dual Enzyme‐Like Activities for Deep Pancreatic Cancer Therapy
Authors: Li Shanshan , Shang Lu , Xu Bolong , Wang Shunhao , Gu Kai , Wu Qingyuan , Sun Yun , Zhang Qinghua , Yang Hailong , Zhang Fengrong , Gu Lin , Zhang Tierui , Liu Huiyu 
Published: June 2019

AbstractNanozymes have attracted extensive interest owing to their high stability, low cost and easy preparation, especially in the field of cancer therapy. However, the relatively low catalytic activity of nanozymes in the tumor microenvironment (TME) has limited their applications. Herein, we report a novel nanozyme (PtFe@Fe3O4) with dual enzyme‐like activities for highly efficient tumor catalytic therapy. PtFe@Fe3O4 shows the intrinsic photothermal effect as well as photo‐enhanced peroxidase‐like and catalase‐like activities in the acidic TME, thereby effectively killing tumor cells and overcoming the tumor hypoxia. Importantly, a possible photo‐enhanced synergistic catalytic mechanism of PtFe@Fe3O4 was first disclosed. We believe that this work will advance the development of nanozymes in tumor catalytic therapy.
The First Observation of Hidden Hysteresis in an Iron(III) Spin‐Crossover Complex
Authors: Boonprab Theerapoom , Lee Seok J. , Telfer Shane G. , Murray Keith S. , Phonsri Wasinee , Chastanet Guillaume , Collet Eric , Trzop Elzbieta , Jameson Guy N. L. , Harding Phimphaka , Harding David J. 
Published: June 2019

AbstractMolecular magnetic switches are expected to form the functional components of future nanodevices. Herein we combine detailed (photo‐) crystallography and magnetic studies to reveal the unusual switching properties of an iron(III) complex, between low (LS) and high (HS) spin states. On cooling, it exhibits a partial thermal conversion associated with a reconstructive phase transition from a [HS‐HS] to a [LS‐HS] phase with a hysteresis of 25 K. Photoexcitation at low temperature allows access to a [LS‐LS] phase, never observed at thermal equilibrium. As well as reporting the first iron(III) spin crossover complex to exhibit reverse‐LIESST (light‐induced excited spin state trapping), we also reveal a hidden hysteresis of 30 K between the hidden [LS‐LS] and [HS‐LS] phases. Moreover, we demonstrate that FeIII spin‐crossover (SCO) complexes can be just as effective as FeII systems, and with the advantage of being air‐stable, they are ideally suited for use in molecular electronics.
Anisotropic Conductivity at the Single‐Molecule Scale
Authors: Afsari Sepideh , Yasini Parisa , Peng Haowei , Perdew John P. , Borguet Eric 
Published: June 2019

AbstractIn most junctions built by wiring a single molecule between two electrodes, the electrons flow along only one axis: between the two anchoring groups. However, molecules can be anisotropic, and an orientation‐dependent conductance is expected. Here, we fabricated single‐molecule junctions by using the electrode potential to control the molecular orientation and access individual elements of the conductivity tensor. We measured the conductance in two directions, along the molecular plane as the benzene ring bridges two electrodes using anchoring groups (upright) and orthogonal to the molecular plane with the molecule lying flat on the substrate (planar). The perpendicular (planar) conductance is about 400 times higher than that along the molecular plane (upright). This offers a new method for designing a reversible room‐temperature single‐molecule electromechanical switch that controllably employs the electrode potential to orient the molecule in the junction in either “ON” or “OFF” conductance states.
Ultrafast and Highly Selective Uranium Extraction from Seawater by Hydrogel‐like Spidroin‐based Protein Fiber
Authors: Yuan Yihui , Yu Qiuhan , Wen Jun , Li Chaoyang , Guo Zhanhu , Wang Xiaolin , Wang Ning 
Published: June 2019

AbstractFor the practical extraction of uranium from seawater, adsorbents with high adsorption capacity, fast equilibrium rate, high selectivity, and long service life are needed. Herein, a chimeric spidroin‐based super uranyl‐binding protein (SSUP) fiber was designed by fusing the gene of super uranyl‐binding protein (SUP) with the gene of spidroin. SUP endowed the SSUP fiber with high affinity and selectivity to uranium, and spidroin gave the SSUP fiber with high mechanical strength and high reusability. The wet SSUP fiber is a water‐rich hydrogel‐like structure, which provided abundant hydrophilic intermolecular space for the entrance of uranyl ions, and could accelerate the rate for uranium adsorption. In seawater, the SSUP fiber achieved a breakthrough uranium extraction capacity of 12.33 mg g−1 with an ultrashort equilibration time of 3.5 days, suggesting that SSUP fiber might be a promising adsorbent for uranium extraction from the natural seawater.
Derivatization of valproic acid using ferrocene derivatives: Synthesis, characterization and investigation of optical and electrochemical properties
Authors: Rahimpour Keshvar , Jouyban Abolghasem , Teimuri‐Mofrad Reza 
Published: June 2019

New ferrocenyl‐based valproic acid (VPA) ester derivatives were designed and synthesized according to the reaction of appropriate haloalkylferrocene derivatives with VPA in the presence of K2CO3 and a catalytic amount of 18‐crown‐6 ether. Elemental analyses and Fourier transform infrared, 1H NMR, 13C NMR and mass spectra all well confirmed the predicted molecular structure. This is the first report in which ferrocene has been applied in derivatization of VPA as a chromogenic group. The electrochemical properties of the synthesized compounds were studied using cyclic voltammetry measurements, and energies of the frontier molecular orbitals were determined. In addition, the solubilities of the final compounds were studied in distilled water, phosphate buffer (pH = 7.4) and 0.9% (w/v) NaCl solution.
Neutral and Anionic Monomeric Zirconium Imides Prepared via Selective C=N Bond Cleavage of a Multidentate and Sterically Demanding β‐Diketiminato Ligand
Authors: Kurogi Takashi , Chu Jiaxiang , Chen Yaofeng , Mindiola Daniel J. 
Published: June 2019

AbstractA sterically encumbering multidentate β‐diketiminato ligand, tBuL2 (tBuL2=[ArNC(tBu)CHC(tBu)NCH2CH2N(Me)CH2CH2NMe2]−, Ar=2,6‐iPr2C6H3), is reported in this study along with its coordination chemistry to zirconium(IV). Using the lithio salt of this ligand, Li(tBuL2) (4), the zirconium(IV) precursor (tBuL2)ZrCl3 (6) could be readily prepared in 85 % yield and structurally characterized. Reduction of 6 with 2 equiv of KC8 resulted in formation of the terminal and mononuclear zirconium imide‐chloride [C(tBu)CHC(tBu)NCH2CH2N(Me)CH2CH2NMe2]Zr(=NAr)(Cl) (7) as the result of reductive C=N cleavage of the imino fragment in the multidentate ligand tBuL2 by an elusive ZrII species (tBuL2)ZrCl (A). The azabutadienyl ligand in 7 can be further reduced by 2 e− with KC8 to afford the anionic imide [K(THF)2]{[CH(tBu)CHC(tBu)NCH2CH2N(Me)CH2CH2N(Me)CH2]Zr=NAr} (8‐2THF) in 42 % isolated yield. Complex 8‐2THF results from the oxidative addition of an amine C−H bond followed by migration to the vinylic group of the formal [C(tBu)CHC(tBu)NCH2CH2N(Me)CH2CH2NMe2]− ligand in 7. All halides in 6 can be replaced with azides to afford (tBuL2)Zr(N3)3 (9) which was structurally characterized, and reduction with two equiv of KC8 also results in C=N bond cleavage of tBuL2 to form [C(tBu)CHC(tBu)NCH2CH2N(Me)CH2CH2NMe2]Zr(=NAr)(N3) (10), instead of the expected azide disproportionation to N3− and N2. Solid‐state single crystal structural studies confirm the formation of mononuclear and terminal zirconium imido groups in 7, 8‐Et2O, and 10 with Zr=NAr distances being 1.8776(10), 1.9505(15), and 1.881(3) Å, respectively.
Multicentre randomized clinical trial of colonic J pouch or straight stapled colorectal reconstruction after low anterior resection for rectal cancer
Authors: Pucciarelli S , Del Bianco P , Pace U , Bianco F , Restivo A , Maretto I , Selvaggi F , Zorcolo L , De Franciscis S , Asteria C , Urso E D L , Cuicchi D , Pellino G , Morpurgo E , La Torre G , Jovine E , Belluco C , La Torre F , Amato A , Chiappa A , Infantino A , Barina A , Spolverato G , Rega D , Kilmartin D , De Salvo G L , Delrio P 
Published: June 2019

Abstract

Background
Colonic J pouch reconstruction has been found to be associated with a lower incidence of anastomotic leakage than straight anastomosis. However, studies on this topic are underpowered and retrospective. This randomized trial evaluated whether the incidence of anastomotic leakage was reduced after colonic J pouch reconstruction compared with straight colorectal anastomosis following anterior resection for rectal cancer.

Methods
This multicentre RCT included patients with rectal carcinoma who underwent low anterior resection followed by colorectal anastomosis. Patients were assigned randomly to receive a colonic J pouch or straight colorectal anastomosis. The main outcome measure was the occurrence of major anastomotic leakage. The incidence of global (major plus minor) anastomotic leakage and general complications were secondary outcomes. Risk factors for anastomotic leakage were identified by regression analysis.

Results
Of 457 patients enrolled, 379 were evaluable (colonic J pouch arm 190, straight colorectal arm 189). The incidence of major and global anastomotic leakage, and general complications was 14·2, 19·5 and 34·2 per cent respectively in the colonic J pouch group, and 12·2, 19·0 and 27·0 per cent in the straight colorectal anastomosis group. No statistically significant differences were observed between the two arms. In multivariable logistic regression analysis, male sex (odds ratio 1·79, 95 per cent c.i. 1·02 to 3·15; P = 0·042) and high ASA fitness grade (odds ratio 2·06, 1·15 to 3·71; P = 0·015) were independently associated with the occurrence of anastomotic leakage.

Conclusion
Colonic J pouch reconstruction does not reduce the incidence of anastomotic leakage and postoperative complications compared with conventional straight colorectal anastomosis. Registration number NCT01110798 (http://www.clinicaltrials.gov).