bluuebunny/crossref_metadata_2025_split huggingface dataset:
Family Members’ Experiences With Bereavement in the Intensive Care Unit
Authors: Jones Casey , Puntillo Kathleen , Donesky Doranne , McAdam Jennifer L. 
Published: July 2018

Background
Losing a loved one in the intensive care unit can be challenging for families. Providing bereavement support may assist in the grieving process.

Objective
To describe family members’ experiences with bereavement after the death of a loved one in the intensive care unit.

Methods
This secondary analysis used an exploratory, descriptive design to study family members’ experiences with bereavement. Family members of patients from 2 intensive care units in a tertiary medical center in the western United States participated. Audiotaped telephone interviews using a semistructured questionnaire were conducted. A qualitative, descriptive technique was used for data analysis. Two independent raters coded transcripts of audiotaped interviews with family members about their bereavement experiences.

Results
Seventeen family members participated in the study. Most participants were female (n = 12; 71%) and spouses of deceased patients (n = 14; 82%), and their mean (SD) age was 62.4 (10.0) years. Three themes emerged: (1) bereavement was an individual experience; (2) situations occurring during the intensive care unit encounter remained significant for family members beyond a year after the death; and (3) social, cultural, spiritual, and religious events after the death hold importance for families of patients in the intensive care unit.

Conclusions
Bereavement is a challenging experience for families of deceased intensive care unit patients. The themes identified in this study add insight into the experiences of these family members. The results of this study may guide future interventions to help support bereaved families of intensive care unit patients.
Educational Intervention to Improve Delirium Recognition by Nurses
Authors: Blevins Cheri S. , DeGennaro Regina 
Published: July 2018

Background
Delirium poses increased morbidity and mortality risks for hospitalized patients. Underrecognition by health care providers contributes to poor outcomes for patients. Little has been published about methods used to teach health care providers how to screen for delirium using the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).

Objective
To evaluate the effectiveness of a multimodal educational intervention for nurses in the medical intensive care unit to improve their knowledge and skills regarding delirium and delirium recognition.

Methods
An educational intervention was done in the medical intensive care unit of an academic medical center. Effectiveness was evaluated via a quasi-experimental design and using preintervention and postintervention assessments. Procedural correctness of performing the CAM-ICU delirium screening also was measured.

Results
Nurses participated in 1 small-group session (n = 34). Fifteen sessions were conducted from June to September 2016, and assessments were completed before and after the intervention. The sample consisted of predominantly nurses with a bachelor’s degree (56%) who had 1 to 5 years’ experience (59%). Mean scores overall and on the knowledge subscale differed significantly (P &lt; .001) from before to after the intervention. No correlation was found between demographic groups and score differences. Seventy-nine percent of participants used the tool correctly after the intervention.

Conclusions
The educational intervention provided for these nurses further validated published reports of the benefits of an educational program about delirium. The content of the educational intervention should be targeted for the setting, the risk factors for the patient population in question, and the specific delirium screening tool used.
Patientsâ€™ self-evaluation of symptoms, signs and compliance to therapy for heart failure surveillance: A pilot study on identification of worsening heart failure
Authors: Palmieri Vittorio , Palermo Antonio 
Published: July 2018

In patients with chronic heart failure (HF), it is unclear whether self-evaluation of HF-related symptoms and signs may contribute to the surveillance of clinical stability over time or the early identification of worsening HF. Â Â Therefore, HF-related symptoms and signs, and compliance to therapy were investigated by a self-administrated questionnaire in patients hospitalized due to worsening HF (cases) as well in those with stable HF (controls).Â The temporal interval of interest for the questionnaire focused on 2 to 7 days before the hospitalization of the control visit. Â A method called â€œclassicâ€ extrapolated a surveillance score by 4 questions revealing HF-related symptoms or signs (higher score indicative of more symptoms or sings reported).Â Alternatively, 3 additional questions enriched the â€œclassicâ€ questionnaire, including one on whether the health status was perceived as stable, improved or worsening.Â The score from â€œperceived health statusâ€Â inquiry was used as â€œconditional factorâ€ to computed the surveillance score as: conditional factor + [conditional factor X (the sum of the points yielded by the responses to each question on symptoms, sings and compliance to therapy)]. Â Among 51 patients hospitalized due to worsening HF and 104 with chronic HF (retrospective study), the area under the curve (receiver operating characteristic) discriminating worsening HF was 0.90 by the classic, and 0.96 by the conditional method (both p<0.001), yielding error rates of 2 in 10 by the classic and 1 in 10 by the conditional method.Â In a pilot longitudinal study in 37 ambulatory HF patients from a different population source, predicting worsening HF by alternative questionnaires within 12 weeks from the visit yielded consistent results.Â In conclusion, patientsâ€™ self-monitoring symptoms, signs and compliance by a standardized questionnaire and a conditional method for generating relative a score, may be a promising method for HF stability surveillance.
Real-World Effectiveness of Intravenous Stroke Thrombolysis is more than the Expectation of Practicing Neurologists
Authors: Ghafoor Fazal , Khan Firosh , Shehna Abdulkhader 
Published: July 2018

ABSTRACT
Background: The objective of the study was to compare the actual results of intravenous thrombolytic therapy (IVTT) in acute ischemic stroke with results anticipated by neurologists in practice. Methods: Neurologists practicing in Thrissur metropolitan region, covering a population of 1.8 million, were telephonically surveyed about the number of yearly IVTT and their expert opinion/comment about effects of thrombolysis. This was compared with the results of IVTT from a single institution in the same region from 2012 to 2016. Results: Eight neurologists in the region give approximately 140–150 IVTT per year. Nearly 20%–40% (median 32%) patients have good outcome, 5%– 10% (median 9%) have intracerebral hematoma (ICH), and 25%–35% (median 30%) have death/bad outcome. Two neurologists from a tertiary care hospital in the region treated 122 cases of ischemic strokes with IVTT from 2012 to 2016. Age ranged from 8 to 88 years and 88 were males. Average delay in reaching hospital was 138.1 min and the door-to-needle time was 56.3 min. There were 26 cases of posterior-circulation strokes and 14 cases of cardioembolic strokes. At presentation, average National Institute of Health Stroke Scale (NIHSS) was 14.7; Modified Rankin Scale (mRS) 0.4; and CT Alberta Stroke Program Early Computerized Tomography Scores was 9.5. Good and sustained benefit (GSB) (>4 reduction in NIHSS at 24 h and 7 days) was there in 49% and no improvement (NI)/worsening in 36%. mRS 0–2 at discharge/30 days was documented in 57.3%. Symptomatic ICH was 10% (12/122) and mortality rate was 11.5% (14/122). GSB in posterior circulation strokes was 69.2% and NI/worsening in only 7.7%. mRS was 0–2 in 77% of posterior circulation strokes. Conclusion: Contrary to the popular belief of the practicing neurologists, IVTT has a high percentage of good outcome with a reasonable bleeding risk and low rates of absolute futility.
-Rota–Baxter Operators, Infinitesimal Hom-bialgebras and the Associative (Bi)Hom-Yang–Baxter Equation
Authors: Liu Ling , Makhlouf Abdenacer , Menini Claudia , Panaite Florin 
Published: July 2018

AbstractWe introduce the concept of a
$\{\unicode[STIX]{x1D70E},\unicode[STIX]{x1D70F}\}$
-Rota–Baxter operator, as a twisted version of a Rota–Baxter operator of weight zero. We show how to obtain a certain
$\{\unicode[STIX]{x1D70E},\unicode[STIX]{x1D70F}\}$
-Rota–Baxter operator from a solution of the associative (Bi)Hom-Yang–Baxter equation, and, in a compatible way, a Hom-pre-Lie algebra from an infinitesimal Hom-bialgebra.
Security Design
Authors: Kępka Paweł 
Published: July 2018

The article presents issues related to security design including, among others, the classification of security design, criteria for its division, the essence of design, security interests and objectives, security determinants (environment), concepts for safety-enhancing activities under specified conditions, security potential and the concept of security enhancing activities. The considerations are based on the assumption that security is first and foremost based on the need to protect against the real risks posed by elements that could negatively affect individuals, communities or entire countries. On the other hand, the long history, beyond the defined approach to providing security, resulting strictly from the willingness to live in a specific environment
(space), indicates cases in which the sense of security is related to the authority, capabilities, quality of assets and resources possessed. Both of the approaches presented emphasise that, regardless of their attitude, the issue of protection of human life and health is the most important
category of things to be protected. The first approach indicates a reactionary character, closely related to intervention in respect of a given threat (real or imaginary), while the second one draws the perspective of organising the security potential that constitutes the strength of the individual in general, including the case of a real threat. It is a sign of preparing resources (legal, organisational, material, financial, informational) for the potential threat from nature, another person or a country. The concepts defined for preparing for what becomes a threat to the protected values are not only logical, but can also be seen in a hierarchical way. The proof in this case is that, first of all, people repel what threatens them here and now and only then do they think about building their security potential as an answer to what they may face in the future.
Espacios y realidades urbanas: procesos de intervención a través de la práctica social
Authors: Sosa Sánchez Roxana , Jivkova Semova Dimitrina 
Published: July 2018

RESUMEN:
El crecimiento desmedido de las grandes ciudades vinculado a la urbanización como fenómeno constante en el paisaje actual del territorio, origina un espacio público cada vez más reducido frente a los efectos de la globalización, afectando finalmente a la interacción entre los ciudadanos. Uno de los retos actuales de la política urbana no es otro que subrayar la importancia de las dinámicas de proactividad y pensamiento crítico-innovador en el espacio público como herramientas para la articulación de la múltiple dimensión urbana. Se trata de prácticas orientadas a la implicación activa por parte de los ciudadanos en el proceso de planeamiento y configuración, a nivel político y social, de su ciudad.
Esta investigación, basada en el proyecto europeo Erasmus+ Artivism: artistic practices as instruments for social transformation, actualmente en curso, se focaliza en los problemas de participación social de los jóvenes y la ciudadanía activa, y pretende responder a cuestiones relevantes en el proceso de conformación urbana tales como ¿cuál es la percepción de los jóvenes acerca del espacio público?, ¿qué tipología de conflictos sociales/urbanos perciben y cómo se podrían detectar en un espacio físico y/o virtual?
Análisis de la funcionalidad y usabilidad de las visualizaciones de información online de Politibot
Authors: Gonzales Hada M. Sánchez , Sánchez Gonzáles María 
Published: July 2018

El presente artículo recoge los resultados de una investigación realizada sobre la startup Politibot, un chatbot o bot conversacional especializado en contenidos políticos, surgido durante la campaña electoral de junio de 2016 en España a través de Telegram, que brinda también a los suscriptores visualizaciones de datos interactivas y multimedia y un análisis de los patrones probables de votación basado en estudios sociológicos.
Basándonos en trabajos anteriores sobre Politibot que muestran hasta qué punto los usuarios diferencian y valoran las noticias de los bots, así como la experiencia de consumo por parte de la audiencia (Sánchez, H. y Sánchez, M., 2017), para este estudio se combinan técnicas como la observación directa y el análisis de las visualizaciones de datos a través del método del estudio de caso. Se indaga en su tipología y temática y se consideran diversos criterios periodísticos, estéticos y formales que inciden en su funcionalidad y potencial usabilidad.
Se concluye que las visualizaciones, como fórmulas interactivas gráficas y audiovisuales, cumplen con los objetivos periodísticos, favorecen la comprensión de la información y propician el consumo personalizado y la interacción de los usuarios sobre ésta.
Prosumo, Swarming y Transmedia. Hacia un nuevo concepto de Stakeholder
Authors: Moya Eugenio 
Published: July 2018

La storytelling transmedia representa hoy una auténtica revolución comunicativa. También un nuevo modelo de negocio. Un nuevo paradigma en el modo de generar y hacer circular los contenidos. La mejor expresión de las redes tecnocomunicativas digitales; unas redes que, al propiciar entornos colaborativos, donde se hace realidad el doing it together, han creado vínculos más estrechos entre los productores de bienes y servicios, las agencias publicitarias, los medios y el público. Internet y las redes sociales han empoderado a los ciudadanos comunes (prosumidores y pronet@rios) y han obligado a las organizaciones y/o marcas a conocer sus intereses y valores a fin de crear conversaciones con ellos, auténticos stakeholders. Ellos no aportan solo opinión; son auténticos inversores. Sus aportaciones, muchas veces intangibles, llegan a ser tan importantes para las marcas/empresas como las económicas que realizan los accionistas. Hablamos de inversiones emocionales, sociales, intelectuales…
En este artículo, presentamos un marco conceptual que permite generar una magnitud intensiva, un grado, en función del continuo participativo que va desde la escasa a la alta inversión. Consideramos que la clave para medir el éxito comunicativo o la eficacia publicitaria radica en esclarecer las gratificaciones que obtienen los prosumers al participar del mundo narrativo y de la estrategia comunicativa de las marcas. Son aquellas las que les hacen comprometerse, hasta su identificación, en la transmedial world-building.de las organizaciones.
Pseudevernia furfuracea (L.) Zopf Liken Türünün Antibakteriyel Aktivitesi Ve Antioksidan Kapasitesinin Araştırılması
Authors: GÜLTEKİN Sinem , ÖZYİĞİTOĞLU Gülşah 
Published: July 2018

Bir mantar (mikobiyont) ve bir
yeşil algin ve/veya siyanobakterinin (fotobiyont) bir araya gelmesiyle oluşan likenler;
bu ortak yaşam sonucunda kendilerine özgü sekonder metabolitler üretirler. Yapılan araştırmalarda likenlerin bu
sekonder metabolitler sayesinde çeşitli biyolojik aktivitelere ve antibakteriyel
etkilere sahip oldukları bildirilmektedir.
Bu çalışmada dalsı liken Pseudevernia furfuracea (L.) Zopf türüne
ait örneklerden elde edilen aseton ekstrelerinin ATCC 29212 Enterococcus faecalis, ATCC 25923 Staphylococcus aureus, CECT 4122 Pseudomonas aeruginosa, ATCC 25922 Escherichia coli suşları üzerindeki
antibakteriyel aktiviteleri disk difüzyon yöntemi ile araştırılmıştır. Ayrıca
aynı liken ekstrelerinin antioksidan kapasiteleri CUPRAC metodu kullanılarak
değerlendirilmiştir. Elde edilen sonuçlara göre, P. furfuracea aseton ekstreleri Gram negatif bakterilere karşı
etkisiz olurken Gram pozitif bakterilerin gelişimini inhibe etmiştir. Antioksidan
olarak ise 9,653 ± 0,102 µg TE/gr değerinde hesaplanan iyi düzeyde aktivite göstermiştir. P. furfuracea liken türünün farmakoloji
alanında doğal kaynak olarak kullanılabileceği öngörülmektedir.
The Culture of Afro-Brazilian Care: Barber-Bleeder of Imperial Brazil and the Legacy for the Nursing Profession / Cultura dos Cuidados Afro-Brasileiros: Barbeiro-Sangrador do Brasil Imperial e Legado para Enfermagem
Authors: Barbosa Lana Rodrigues , AGUIAR SIMONE , Nassar Pedro , Sant´Anna Andreia Neves , Porto Fernando 
Published: July 2018

Objetivo: Descrever, analiticamente, e comentar as práticas de cuidado do barbeiro-sangrador, na diáspora Brasil imperial, como elementos para a construção dos saberes no campo da saúde. Método: Pesquisa na abordagem da história cultural com ênfase na trajetória dos povos negros. Descrição e análise realizaram-se no livro “História Geral da Medicina Brasileira”, relacionando-o com as obras de Debret, sobre os cuidados exercidos por negros. Resultados: Foram encontradas descrições do ofício do barbeiro- sangrador, quando relatado na execução do cuidado, mais o instrumental que utilizava e qual era sua posição diante da sociedade. Por Debret localizaram-se três aquarelas de práticas dos barbeiro-sangradores. Conclusão: Revelou-se a existência de um legado cultural afrodescendente no âmbito do cuidado, mesmo diante da querela do saber popular e científico. Porém, o saber popular esteve e está presente na prática e quiçá nas dobras dos cuidados prestados atualmente. Descritores: Cultura, História, Cuidado.
Human Milk Collection and Utilization in a Milk Bank From a Municipality of Paraná State / Captação e Aproveitamento de Leite Humano em um Banco de Leite de um Município do Estado do Paraná
Authors: Soares Larissa Gramazio , Dolinski Dirléia , Wagner Livia Perissé Baroni , Santos Leandra da Silva Faria dos , Soares Leticia Gramazio , Mazza Verônica de Azevedo 
Published: July 2018

Objetivo: Descrever a captação, aproveitamento e o perfil das doadoras de Leite Humano em um Banco de leite de um município do Estado do Paraná. Métodos: Estudo epidemiológico de corte transversal com abordagem quantitativa. Os dados foram coletados entre janeiro e fevereiro de 2015, a partir de fichas arquivadas no primeiro ano de funcionamento, 2013-2014. Resultados: As doadoras eram da faixa etária de 26 a 32 anos, casadas, do lar, tinham 1 ou 2 filhos, foram indicadas por serviços de saúde e a principal motivação para a doação foi o excesso de leite. A média de leite doado foi de 1,4 litro, a maioria na fase madura. Houve perda significativa de leite devido a sujidade. Conclusão: Faz-se necessário, o desenvolvimento de ações para a captação de doadoras, para diminuição das perdas de leite e para educação permanente dos profissionais de saúde envolvidos, a fim de otimizar o funcionamento do serviço.
Agility MLC transmission optimization in the Monaco treatment planning system
Authors: Roche Michael , Crane Robert , Powers Marcus , Crabtree Timothy 
Published: June 2018

AbstractThe Monaco Monte Carlo treatment planning system uses three‐beam model components to achieve accuracy in dose calculation. These components include a virtual source model (VSM), transmission probability filters (TPFs), and an x‐ray voxel Monte Carlo (XVMC) engine to calculate the dose in the patient. The aim of this study was to assess the TPF component of the Monaco TPS and optimize the TPF parameters using measurements from an Elekta linear accelerator with an Agility™ multileaf collimator (MLC). The optimization began with all TPF parameters set to their default value. The function of each TPF parameter was characterized and a value was selected that best replicated measurements with the Agility™ MLC. Both vendor provided fields and a set of additional test fields were used to create a rigorous systematic process, which can be used to optimize the TPF parameters. It was found that adjustment of the TPF parameters based on this process resulted in improved point dose measurements and improved 3D gamma analysis pass rates with Octavius 4D. All plans calculated with the optimized beam model had a gamma pass rate of > 95% using criteria of 2% global dose/2 mm distance‐to‐agreement, while some plans calculated with the default beam model had pass rates as low as 88.4%. For measured point doses, the improvement was particularly noticeable in the low‐dose regions of the clinical plans. In these regions, the average difference from the planned dose reduced from 4.4 ± 4.5% to 0.9 ± 2.7% with a coverage factor (k = 2) using the optimized beam model. A step‐by‐step optimization guide is provided at the end of this study to assist in the optimization of the TPF parameters in the Monaco TPS. Although it is possible to achieve good clinical results by randomly selecting TPF parameter values, it is recommended that the optimization process outlined in this study is followed so that the transmission through the TPF is characterized appropriately.
Palladium‐Catalyzed Carbonylative Cyclization of Terminal Alkynes and Anilines to 3‐Substituted Maleimides
Authors: Xu Jian‐Xing , Wu Xiao‐Feng 
Published: June 2018

AbstractHerein, we describe an interesting palladium‐catalyzed protocol for the carbonylative synthesis of 3‐substituted maleimides. By annulation of simple anilines with terminal alkynes under carbon monoxide pressure, the desired 3‐substituted maleimides can be obtained in 50–85% yields. Additionally, with the addition of phosphine ligand, maleic acid isoimide can be obtained from the same substrates as well. With the presence of K2S2O8, the obtained maleic acid isoimide can be completely transformed to the corresponding maleimide.magnified image
A Light‐Up Probe with Aggregation‐Induced Emission for Real‐Time Bio‐orthogonal Tumor Labeling and Image‐Guided Photodynamic Therapy
Authors: Hu Fang , Mao Duo , Kenry  , Cai Xiaolei , Wu Wenbo , Kong Deling , Liu Bin 
Published: June 2018

AbstractBio‐orthogonal tumor labeling is more effective in delivering imaging agents or drugs to a tumor site than active targeting strategy owing to covalent ligation. However, to date, tumor‐specific imaging through bio‐orthogonal labeling largely relies on body clearance to differentiate target from the intrinsic probe signal owing to the lack of light‐up probes for in vivo bio‐orthogonal labeling. Now the first light‐up probe based on a fluorogen with aggregation‐induced emission for in vivo bio‐orthogonal fluorescence turn‐on tumor labeling is presented. The probe has low background fluorescence in aqueous media, showing negligible non‐specific interaction with normal tissues. Once it reacts with azide groups introduced to tumor cells through metabolic engineering, the probe fluorescence is lightened up very quickly, enabling rapid tumor‐specific imaging. The photosensitizing ability was also used to realize effective image‐guided photodynamic tumor therapy.