bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hematoma espinal epidural espontáneo asociado a tratamiento anticoagulante con acenocumarol: a propósito de un caso. [Spontaneous spinal epidural hematoma in patients treated with acenocumarol: A case study]
Authors: Chuliá Carrasco Verónica , Gómez Barbero Patricia 
Published: August 2019

El hematoma epidural espontáneo es una entidad muy poco frecuente que supone una urgencia neurológica. Su presentación es muy variable, desde un dolor de espalda hasta una tetraplejia, según la gravedad y el nivel de compresión. Se comunica el caso de un paciente cardiópata de 71 años, tratado con acenocumarol, que presentó un hematoma epidural de modo espontáneo. Al inclinarse hacia el suelo, el paciente, que no tenía síntomas, sufrió un dolor brusco cervical seguido de debilidad en los miembros superiores e inferiores. Ante la sospecha clínica de una compresión medular, se decide realizar una resonancia magnética de urgencia, que mostró un hematoma de localización epidural con extensión desde C4 hasta T8. El diagnóstico urgente y el tratamiento de descompresión precoz son fundamentales para reducir al mínimo los daños neurológicos posteriores permanentes. AbstractSpontaneous spinal epidural hematoma is an uncommon condition and a neurological emergency. The clinical presentation of this type of hematoma is very variable, ranging from a backache up to a quadriplegia, according to the severity and the site of compression. Here, we discuss the clinical case of a 71-year-old patient with heart problems, under previous treatment with acenocumarol, that suffered a spontaneous epidural hematoma. The patient, previously asymptomatic, presented, sudden cervical pain when he bent over, followed by weakness in the lower and the upper limbs. Due to the clinical suspicion, an emergency MRI was performed, showing an epidural hematoma extending from C4 to T8. Early diagnosis and decompressive treatment are mandatory to minimize permanent neurological damage.
Hidrogeles de polimerización in situ para la regeneración de cartílago articular. [In-situ-forming hydrogels for articular cartilage repair]
Authors: Rodríguez-Fontán Francisco , Pascual-Garrido Cecilia 
Published: August 2019

Una significativa cantidad de adultos jóvenes activos sufre lesiones condrales focales. Estas lesiones, si no se tratan, pueden progresar hacia la artrosis, que es una de las principales enfermedades musculoesqueléticas debilitantes y de gran carga económica que afectan a toda sociedad. Pese a los tratamientos quirúrgicos disponibles para la reparación de defectos condrales focales sintomáticos que mejoran la calidad de vida a mediano plazo, hay un mayor riesgo de progresión hacia la artrosis prematura. Los tratamientos biológicos (células madre, bioingeniería tisular) han avanzado a grandes pasos en los últimos años. La bioingeniería es un área que ha progresado en la regeneración de cartílago articular y que potencialmente podría progresar en el terreno de tratamientos articulares, promoviendo la regeneración y evitando la degeneración. Las células madre y los hidrogeles pueden proveer un tejido símil biológico de comportamiento dinámico-funcional equivalente que induce la regeneración tisular al ser degradado y reemplazado gradualmente. El abordaje consiste en colocar un hidrogel precursor o un biomaterial tridimensional impreso dentro del defecto condral por ocupar para inducir la regeneración. Esta revisión se focaliza en el uso actual y futuro de hidrogeles y bioimpresión tridimensional para la regeneración de cartílago articular en el tratamiento de lesiones condrales focales y proporciona datos preliminares de dos estudios piloto en animales. AbstractA significant number of young active adults are affected by focal chondral lesions. These lesions, if left untreated, will progress to osteoarthritis (OA). OA is one of the main debilitating musculoskeletal diseases and leads to a high economic and social burden. Despite surgical cartilage repair for focal chondral lesions, which improve patient-reported outcomes at short- and mid-term, there is a risk of early OA progression. Biological treatments (i.e., stem-cell therapy, bioengineering) have made great progress in the last years. Tissue engineering is an evolving field for articular cartilage repair which could potentially be used for the treatment of focal chondral lesions, promoting regeneration and preventing joint surface degeneration. Stem cells and hydrogels may provide a functional, dynamic and biologically equivalent tissue that promotes tissue regeneration while being gradually degraded and replaced. The standard approach to tissue engineering consists in delivering cells within a hydrogel or a three-dimensional printed biomaterial scaffold into the chondral lesion to induce regeneration. This review focuses on the current and future use of hydrogels and tissue scaffold bioprinting for the treatment of focal chondral lesions, and provides preliminary data from two pilot animal studies.
Az extrém alacsony születési súlyú koraszülöttek hyperglykaemiájának korai és késői szövődményei
Authors: Turai Réka , Schandl Márton Ferenc , Dergez Timea , Vass Réka Anna , Kvárik Tímea , Horányi Eszter , Balika Dorottya , Mammel Barbara , Gyarmati Judit , Fónai Fruzsina , Vida Gabriella , Funke Simone , Gaál Valéria , Reglődi Dóra , Ertl Tibor 
Published: August 2019

Abstract: Introduction: During recent decades, the perinatal mortality of extremely low-birth weight infants has decreased. An important task is to recognize complications of prematurity. Aim: We made an attempt to explore the relationship between complications of prematurity and neonatal hyperglycemia. Method: From 1 January 2014 to 31 December 2017, 188 infants with birth weight below 1000 g were admitted. For each infant, the frequencies of hyperglycemia (blood glucose >8.5 mmol/l), retinopathy of prematurity, intraventricular hemorrhage, and bronchopulmonary dysplasia were determined. Animal studies were performed in Sprague Dawley rats. Hyperglycemia was achieved by intraperitoneal injection of streptozotocin (100 mg/kg). On the 7th day of life, aorta sections were prepared and stained with hematoxylin eosin. Wall thickness was measured using QCapture Pro 7 image analysis software. Results: The mean ± SD gestational age and birth weight were 27.1 ± 2.2 weeks and 814.9 ± 151.9 g; 33 infants (17.5%) died. Hyperglycemia was confirmed in 62 cases (32.9%), and insulin treatment was given to 43 infants (22.8%). The gestational age and birth weight of the hyperglycemic infants were significantly lower (p<0.001), the incidence of severe retinopathy (p = 0.012) and the mortality of insulin-treated patients were higher (p = 0.02) than in normoglycemic infants. Among survivors (n = 155), we found by logistic regression analysis that hyperglycemia was a risk factor for severe retinopathy (p<0.001). In the rat model, neonatal hyperglycemia caused significant thickening of the aortic wall. Conclusion: Our studies indicate that hyperglycemia is common in extremely low birth-weight infants. Monitoring of these infants for retinopathy of prematurity, kidney dysfunction, and hypertension is recommended. Orv Hetil. 2019; 160(32): 1270–1278.
Analysis of the Seismicity in the Jalisco Block from June to December 2015
Authors: Marín‐Mesa Tatiana , Núñez‐Cornú Francisco J. , Suárez‐Plascencia Carlos 
Published: August 2019

ABSTRACTWe present the first study of seismicity in the region of the Jalisco Block using data recorded by the Jalisco Seismic Accelerometric Telemetric Network between June and December 2015. During this period, 683 local earthquakes with magnitudes between 1.0<ML≤4.0 were identified and relocated with Hypo71PC. From this catalog, we identify a heterogeneous hypocentral distribution with six continental crustal seismogenic areas. We also observed seismicity associated with the subduction process that extends 180 km from the Mesoamerican trench, which suggests an estimated dip angle of the slab between 22° and 31°. A subtle dip also suggests oblique subduction toward the Colima rift zone and bending of the Rivera plate. These observations are in agreement with previous partial regional studies using local seismic networks. Two seismic swarms were observed in this period, one in the Bahia de Banderas seismogenic zone, and a second in the Guadalajara Metropolitan zone. We note two areas on the northern coast of Jalisco with meager rates of seismicity.
Eficacia e ineficacia de la comunicación horizontal en los movimientos sociales. Caso análisis: “oposiciones justas en Cataluña 2011”
Authors: Echazarreta Carmen , Vinyals Manel , Gema Martín Teresa 
Published: August 2019

Las redes sociales están generando un amplio entramado de comunicaciones, a distintos niveles y con distintos objetivos. En este artículo analizamos un caso concreto, fruto de la observación y el seguimiento de un grupo creado para la defensa de unas oposiciones justas para el acceso a la función pública de docentes para educación secundaria. Se trata de un grupo creado como reacción a una serie de posibles irregularidades. Interesa observar tanto la creación del grupo, como las distintas fases que sigue la evolución, muy ligada a la efectividad de los procesos de comunicación, y la vinculación de estos últimos a las posibilidades de acción y resolución del conflicto que existe en la base del grupo.
Los blogs corporativos en las empresas españolas. Uso y papel que desempeñan en la estrategia comunicativa ante la irrupción de las redes sociales
Authors: Navarro Ruiz Cristina 
Published: August 2019

Desde su nacimiento, la llamada web 2.0 o web social ha puesto a disposición de las empresas un arsenal de herramientas que, por primera vez, pueden hacer realidad las promesas de diálogo, transparencia, consenso y entendimiento mutuo con los públicos, meta hacia la que deben avanzar. Debido a su carácter pionero en el ámbito de la comunicación online, los blogs ofrecen una interesante perspectiva a la hora de analizar el papel que están jugando las nuevas tecnologías dentro de la estrategia de comunicación de las empresas, su evolución y las transformaciones que han experimentado tras el estallido de las redes sociales.En definitiva, este estudio trata de explicar la forma en que los profesionales de las relaciones públicas han incorporado las bitácoras; cómo desarrollan sucapacidad interactiva y dialógica; cómo encajan los blogs en el plan de relaciones públicas; cuáles son sus ventajas e inconvenientes respecto a otros medios; qué departamento dentro de la empresa se encarga de su gestión y cuáles son sus perspectivas de futuro ante la rápida penetración de las redes sociales.
El Plan Nacional de Desarrollo (PND) y la Ley Estatutaria de Salud (LES)
Authors: Prieto Ávila Cesar Augusto 
Published: August 2019

A propósito del debate nacional abierto sobre las decenas de iniciativas planteadas en el PND radicado ante el Congreso Nacional, podemos intentar un análisis académico sobre lo relacionado con los que nos incumbe, el tema de la Salud.
Digamos antes que nada que La ley 1751 de 2015 (conocida como LES) aprobada por el congreso así como la Sentencia de la Corte Constitucional sobre la revisión de constitucionalidad de la misma, se constituyen en uno de los adelantos más significativos que puede registrar la historia de la Seguridad Social Colombiana en los últimos cien años de vida política, pues se resaltan puntos fundamentales que surgen como cambios básicos y estructurales del actual Sistema Nacional de Salud que rige desde 1993, dándole rango constitucional a conceptos tan importantes como el cambio del sistema de aseguramiento por el de un verdadero sistema nacional de salud, en el cual es el Estado el único responsable de garantizar el derecho fundamental a la salud como un derecho individual y colectivo e irrenunciable de todos los habitantes del país sin intermediación y sin la intervención de capitales privados.
Es conveniente hacer algunas anotaciones con respecto a la Ley, ya que se considera que la sentencia de la Corte Constitucional no desvirtúa el espíritu de la ley, sino que, por el contrario, le imprime mayor consistencia de tipo jurídico y produce un cambio trascendental en la legislatura constitucional del país. La reforma fundamental es que se cambia un sistema de aseguramiento por un verdadero Sistema Nacional de Salud. La Corte además reafirma en varios apartes de la Ley la naturaleza de los dineros utilizados en el Sistema de Salud al enfatizar que son “recursos públicos asignados a la salud”, es un precedente muy importante para la lucha contra la corrupción.
O FRACASSO DAS PRÁTICAS ESTATAIS COMO SUA JUSTIFICATIVA: Projetos de Policiais-Professores na Cidade de Deus
Authors: Motta Luana Dias 
Published: August 2019

Este texto problematiza os esforços estatais de conter o conflito contemporâneo nas margens urbanas, a partir de um caso empírico: projetos conduzidos por policiais militares cedidos pela Unidade de Polícia Pacificadora da Cidade de Deus. A partir de etnografia que acompanhou a rotina desses policiais-professores e em diálogo com uma perspectiva desessencializada do Estado, argumento que as explicações para os problemas das favelas estão assentadas no que seriam as características da comunidade. Essas características explicariam a manutenção dos problemas sociais e da violência, a despeito dos projetos. Nessa narrativa, muito comum nas políticas para pobres, oblitera-se uma reflexão sobre a concepção e a implementação da política. A ineficácia dos projetos emerge como um indicador de quão difícil é, à comunidade, fazer do fracasso a justificativa para a manutenção dessas mesmas políticas.Palavras-chave: Projetos sociais. Policiais militares. Conflito urbano. Pobreza. Violência.
Sintesis de Zeolitas utilizando como materia prima lodos de los procesos de anodizado de aluminio
Authors: Peñafiel-Villarreal Fausto , Martínez-Mañez Ramón 
Published: August 2019

Se encontró, por absorción atómica y escaneado electrónico de barrido concentraciones entre 25,3% y 39,45 % de aluminio, además de sodio, magnesio, calcio y silicio en los lodos de anodizado de aluminio de una industria que opera en Ecuador. Por lo tanto el objetivo del presente trabajo fue investigar a nivel de laboratorio, la posibilidad de utilizar estos residuos como fuente de precursores en la síntesis de zeolitas.
Utilizando una solución de hidróxido de sodio en concentraciones 0,5M, 1,0 M, 1,5 M, 2,0 M, 2,5 M y 3,0 M en mezcla con Na2SiO3 hidratado, se ajustó la composición química de 20 g de muestra de lodo a una constante de relación molar SiO2/Al2O3 de 1,24 para todas las pruebas y variando las relaciones molares de Na2O/Al2O3; Na2O/SiO2 y H2O/ Na2O, conforme a la variación de la concentración de la solución de hidróxido de sodio. Se mantuvo constante la temperatura de fusión de precursores, envejecimiento y cristalización de la zeolita a 100°C y tiempo de reacción de 48 horas.
Mediante la técnica de difracción de rayos X, se identificó la síntesis de la zeolita Na-P1 GIS , con tres tipos de mineralogía, además las zeolitas ACP-1 y Sodalita Octahidrato. Las imágenes electrónicas muestran un producto con una morfología bien definida. Las mejores condiciones del resultado fueron la concentración 1,5 M de la solución de sosa y relaciones molares 1,24 de SiO2/Al2O3; 0,61 de Na2O/Al2O3; 2,02 de SiO2/Na2O; 15,51, de H2O/ Na2O y 7,68 de H2O/ SiO2.
A mayores concentraciones de sosa se obtienen las mismas zeolitas, como lo demuestran los difractogramas de rayos X, pero las imágenes electrónicas de los productos muestran cristales deformados, posiblemente por el exceso de sosa.
Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity
Authors: Sharma Monika , Schlegel Martin , Brown Emily J. , Sansbury Brian E. , Weinstock Ada , Afonso Milessa S. , Corr Emma M. , van Solingen Coen , Shanley Lianne C. , Peled Daniel , Ramasamy Ravichandran , Schmidt Ann Marie , Spite Matthew , Fisher Edward A. , J.Moore Kathryn 
Published: August 2019

Abstract
Macrophages accumulate prominently in the visceral adipose tissue (VAT) of obese humans and high fat diet (HFD) fed mice, and this is linked to insulin resistance and type II diabetes. While the mechanisms regulating macrophage recruitment in obesity have been delineated, the signals directing macrophage persistence in VAT are poorly understood. We previously showed that the neuroimmune guidance cue netrin-1 is expressed in the VAT of obese mice and humans, where it promotes macrophage accumulation. To better understand the source of netrin-1 and its effects on adipose tissue macrophage (ATM) fate and function in obesity, we generated mice with myeloid-specific deletion of netrin-1 (Ntn1
fl/fl
LysMCre
+/–; Ntn1Δmac). Interestingly, Ntn1mac mice showed a modest decrease in HFD-induced adiposity and adipocyte size, in the absence of changes in food intake or leptin, that was accompanied by an increase in markers of adipocyte beiging (Prdm16, UCP-1). Using single cell RNA-seq, combined with conventional histological and flow cytometry techniques, we show that myeloid-specific deletion of netrin-1 caused a 50% attrition of ATMs in HFD-fed mice, particularly of the resident macrophage subset, and altered the phenotype of residual ATMs to enhance lipid handling. Pseudotime analysis of single cell transcriptomes showed that in the absence of netrin-1, macrophages in the obese VAT underwent a phenotypic switch with the majority of ATMs activating a program of genes specialized in lipid handling, including fatty acid uptake and intracellular transport, lipid droplet formation and lipolysis, and regulation of lipid localization. Furthermore, Ntn1Δmac macrophages had reduced expression of genes involved in arachidonic acid metabolism, and targeted LCMS/MS metabololipidomics analysis revealed decreases in proinflammatory eicosanoids (5-HETE, 6-trans LTB4, TXB2, PGD2) in the obese VAT. Collectively, our data show that targeted deletion of netrin-1 in macrophages reprograms the ATM phenotype in obesity, leading to reduced adipose inflammation, and improved lipid handling and metabolic function.
Reinforcing Some Kuwaiti Soils with Shredded High-density Polyethylene (HDPE) Bits
Authors: Abdelsalam Ziad , Almashan Nourah , Ismael Nabil 
Published: August 2019

ABSTRACT
Large amounts of shredded high-density polyethylene (HDPE) plastic bits are generated in Kuwait as a by-product of the production of plastic pipes. To find beneficial uses for this waste material, an extensive laboratory testing program was carried out on two local surface sands of Kuwait amended with shredded HDPE bits in amounts varying from 0 percent to 15 percent (by weight). Laboratory tests included sieve analysis, modified proctor compaction, direct shear, consolidation, and permeability tests. The testing measured the effect of increased HDPE content on the different soil properties. The results indicate a reduction of the maximum density of about 20 percent and a substantial increase in the permeability and compressibility. The strength parameters, namely the cohesion, C, and the angle of internal friction, ϕ, increased with increasing HDPE content. Therefore, the use of HDPE plastic bits as an additive to the local soils in Kuwait is beneficial for many practical applications, such as lightweight fill, embankment construction, and as a drainage layer in the construction of landfills.
Biometric Analysis of Nummulites PachoiSaid, 1951 (topotype, Late Lutetian) from El Arag Oasis, Egypt
Authors: Abd El Naby Ahmed , Orabi Orabi , Al Menoufy Safia , Gadallah Mohamed 
Published: August 2019

AbstractNummulites pachoi Said, 1951 is described and illustrated for the first time from topotypic material from the Late Lutetian Mokattam Formation of El Arag Oasis, Egypt, including the first photographs of both microspheric and megalospheric generations. Nummulites pachoi spans the SBZ 16 of Late Lutetian age. This species is phylogenetically parallel to N. praelyelliBoukhary & Kamal, 2003. Although, N. pachoi and N. praelyelli exhibit the same ontogenetic trend, from tight to lax, the development of granulation in the megalospheric form of N. pachoi is a progressive character through time, unlike that in N. praelyelli. Nummulites pachoi is larger, flatter and with an opposite ontogenetic trend compared with Nummulites gizehensis, although both have similar protoconch diameters. The author who first recognized the name “pachoi” as a species-level designation should be given credit for naming the species. Because Said (1951) raised the rank of de la Harpe's race pachoi to specific level, according to the rules of zoological nomenclature, Said should be recognized as the author of the species.
The Paleogeographic Evolution of the Orthophragminids of the Paleogene
Authors: BouDagher-Fadel Marcelle K. , Price G. David 
Published: August 2019

AbstractOrthophragminids are larger benthic foraminifera (LBF) and, together with the nummulitids, were the major rock-forming foraminifera from the middle Paleocene to the late Eocene. Today, porous, LBF-bearing, Paleogene limestones, which occur globally from the Pacific and Atlantic margins of the Americas to the Indo-Pacific, form potentially valuable oil reservoirs, and their biota have formed the basis of the definition of three paleobiogeographic provinces, namely those of the Americas, Tethys, and the Indo-Pacific. The orthophragminids of the western part of the Tethyan Province have been studied extensively, however, the other provinces are less well characterized, and until now the origin and paleogeographic development of this group have not been fully articulated. New material described here allows the clear definition of a fourth, South African paleobiogeographic province, and, when combined with refined biostratigraphic dating based on new material from the Americas, Europe, South Asia and SE Asia, enables their paleogeographic and biostratigraphic evolution to be determined. Critically, the occurrence of cosmopolitan planktonic foraminifera (PF) within LBF assemblages enables the first occurrences of various LBF forms within each province to be dated relative to well-calibrated planktonic zones (PZ). From this, we infer that, like the previously studied lepidocyclinids and nummulitids, the orthophragminids originated in the Americas during the Paleocene, probably between the late Danian (PZ P1c, 63.5 Ma) and the early Selandian (PZ P3a, 61.6 Ma). By the middle Paleocene, the orthophragminids had migrated across the Atlantic to the previously isolated West African coast at the extreme of Tethys, probably during global sea-level low stands at 60.3 Ma and again at 56.4 Ma. Subsequently, the American Province again became isolated. In the Tethys, the orthophragminid migrations followed two paths: northeastward through the Tethyan corridor in the late Paleo-cene (Thanetian), and south in the earliest Eocene (Ypresian) to South Africa. The Tethyan forms evolved during the Eocene into many lineages, which in turn migrated, after a few million years of their first appearances into the Indo-Pacific, where they again became isolated and diversified further. Meanwhile the South African forms remained similar to their American ancestors in both small size and external ornamentation, while their internal evolution closely followed that of Tethys forms, as exhibited by three species of Nemkovella and Discocyclina described here from South Africa (Nemkovella mcmilliana n. sp., Discocyclina davyi n. sp. and D. africana n. sp.).
Gavelinella Breardi, A New Name For the Turonian Gulf Coast Marker Species Anomalina “w”
Authors: Denne Richard A. , Callender Arden D. , Engelhardt-Moore Nancy , Hinote Russell E. , Lowery Christopher M. 
Published: August 2019

Abstract
The name Gavelinella breardi n. sp. is proposed for the Turonian benthic foraminifer informally known as Anomalina “W”. This species is used by industry paleontologists as a marker for the Eagle Ford Group of Texas and has a known stratigraphic range from the Late Cenomanian to the Late Turonian. It is distinguished from the similar species Gavelinella petita and Planulina eaglefordensis by its raised, limbate sutures in early whorls. Another similar form, Anomalina redmondi Petters, is reassigned to the genus Gavelinella.