bluuebunny/crossref_metadata_2025_split huggingface dataset:
The electroclinical features of idiopathic generalized epilepsy patients presenting with fixation‐off sensitivity
Authors: Wang Xiaoli , Zhang Ying , Zhang Wenjuan , Shen Chenxi , Jin Lang , Chen Beibei , Jiang Zhao , Tao James X. , Liu Yonghong 
Published: August 2019

ABSTRACTAims. To determine the electroclinical features of fixation‐off sensitivity (FOS) in patients with idiopathic generalized epilepsy (IGE).Methods. We searched the EEG database using the terms “fixation‐off sensitivity” and “idiopathic generalized epilepsy” over a four‐year period from March 2014 to April 2018 in the Xijing Hospital, Xi’an, China. FOS was evaluated according to the technique proposed by Panayiotopoulos. Photic stimulation procedure and neuropsychological testing were performed during video‐EEG monitoring.Results. FOS was observed in eight patients with several different IGE syndromes, including four with eyelid myoclonia/Jeavons syndrome, two with juvenile myoclonic epilepsy, one with photosensitivity epilepsy, and one with epilepsy with generalized tonic‐clonic seizures only. FOS was associated with seizures in five patients manifesting with eyelid myoclonic, myoclonic, and myoclonic‐tonic‐clonic seizures, and eyelid myoclonic status. FOS coexisted with photosensitivity in six patients as independent EEG features. Neuropsychological testing revealed transitory cognitive impairments associated with FOS.Conclusions. FOS is associated with several different IGE syndromes and may coexist with photosensitivity in the same patient as independent EEG features. FOS may be associated with both clinical seizures and cognitive impairments. Intermittent photic stimulation and registration of different eye conditions with and without fixation will aid the study of the dynamics of the visual system in epilepsy patients. [Published with video sequences onwww.epilepticdisorders.com]
Karma Yaklaşıma Dayalı Bilgisayar Destekli Etkinliklerin İlkokul 4. Sınıf Öğrencilerinin Hoşgörü Değerine Yönelik Tutumlarına Etkisi
Authors: YARAR KAPTAN Seher 
Published: August 2019

Bu araştırmanın amacı, ilkokul 4. sınıf sosyal
bilgiler dersinde hoşgörü değerinin karma yaklaşıma dayalı bilgisayar destekli
etkinliklerle öğretiminin öğrencilerin tutumlarına etkisini belirlemektir.
Tarama modelinin kullanıldığı betimsel bir çalışma olan bu araştırmaya,
2013-2014 eğitim öğretim döneminde Rize ilinde bir ilkokulda öğrenim gören 23’ü
deney, 22’si kontrol grubu olmak üzere toplam 45 ilkokul dördüncü sınıf
öğrencisi katılmıştır. Araştırmada veri toplama aracı olarak “Hoşgörü Tutum
Ölçeği” ve “Kişisel Bilgi Formu”
kullanılmıştır. Veri analizinde aritmetik ortalama, standart sapma, bağımsız t
testi ve tek yönlü ANOVA testi kullanılan araştırma sonucunda ölçeğin alt boyutlarında ve genelinde deney grubu lehine anlamlı
farklılıklar belirlenmiştir Bununla beraber kontrol grubu öğrencilerinin
puanlarında anlamlı bir farklılık elde edilmemiştir.
İlkokul 4. Sınıf Öğrencilerinin Biyomimikri Algılarına Yönelik Yaptıkları Çizimlerin Analizi
Authors: YAKIŞAN Mehmet , VELİOĞLU Dilara 
Published: August 2019

Çalışmanın amacı, ilkokul 4. Sınıf öğrencilerinin hayvanların özelliklerinden yararlanarak geliştirmeyi tasarladıkları teknolojik ürünlerin belirlenmesidir. Bu amaçla Samsun il merkezindeki bir ilkokulun 4. Çalışmanın amacı, ilkokul 4. Sınıf öğrencilerinin hayvanların özelliklerinden yararlanarak geliştirmeyi tasarladıkları teknolojik ürünlerin belirlenmesidir. Bu amaçla Samsun il merkezindeki bir ilkokulun 4. sınıfında öğrenim gören 32’si kız, 26’sı erkek olmak üzere toplam 58 öğrenci araştırmaya katılmıştır. Veri toplama aracı olarak öğrencilerin hayvan özelliklerinden yararlanarak tasarlamayı düşündükleri teknolojik ürünlerle ilgili çizimler kullanılmıştır. Çalışmada öğrencilerden hayvanların özelliklerinden yararlanarak biyomimetik ürünler tasarlamaları ve tasarımları ile ilgili çizimler yapmaları istenmiştir. Çalışma nitel araştırma yöntemlerinden durum çalışması olup verilerin analizinde betimsel analiz kullanılmıştır. Araştırma sonuçlarına göre, öğrencilerin çeşitli hayvanlardaki farklı özelliklerden yaralanarak çok çeşitli teknolojik ürün tasarımı çizdikleri tespit edilmiştir. Öğrencilerin tasarladıkları teknolojik ürünler ile ilgili çizimlerine yaşamış oldukları coğrafi çevreden öğrendiklerinin ve sosyalleştikleri ortamların etkisinin olduğu görülmüştür. Özellikle öğrencilerin bilgisayar vb ortamlarda oynadıkları savaş oyunları ve TV haberi ve filmler gibi ortamlarda gördükleri savaş görüntülerinden dolayı daha çok savaş ve savunma teknolojisine yönelik tasarım ürünlerine yönelik çizimler yaptıkları anlaşılmaktadır.
Santri, Kelas Menengah dan Politik Lokal Indonesia
Authors: Zalpa Yulion 
Published: August 2019

This journal means to give an ilustration function and role of santri, as part of middle class people in Indonesia. The result of this journal shows that political dynamics of santri as the middle class always changes in every era. In colonialism era, a group of santri unite to take an independence. Meanwhile, a group of santri in post-independence era want to dominate with an idea to make Islam as the rules of nation and the government must take the policy to limit it. Consequently, a group of santri show more in practical politics in government and the other strategic position in reformation era. However, the identity of group of santri more dissolved by the interest group and another as a result from their position as middle class. Therefore, the role and identity of a group of santri as middle class show the shortage whwn the differences interest and interference of outsider precisely cause the dissension in that group of santri.

Keyword : santri, middle class, politic.
UPAYA MENINGKATKAN HASIL BELAJAR DAN KEAKTIFAN SISWA MELALUI PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIME TOKEN PADA MATERI INTERAKSI MANUSIA DAN LINGKUNGAN DALAM DINAMIKA LITOSFER KELAS X IPS SMA TAMAN MADYA MALANG
Authors: Wulandari Margareta Aprilia , Sakdiyah Siti Halimatus 
Published: August 2019

Time Token, merupakan salah satu model pembelajaran kooperatif yang paling sederhana, dan merupakan model yang paling baik untuk permulaan bagi para guru yang baru menggunakan pendekatan kooperatif. Penelitian ini bertujuan untuk meningkatkan hasil belajar dan keaktifan belajar siswa kelas X SMA Taman Madya Malang melalui penerapan model pembelajaran Kooperatif Time Token. Berdasarkan hasil observasi dan tes uraian yang diberikan guru ketika proses pembelajaran berlangsung di kelas X IPS SMA Taman Madya Malang, serta informasi yang diperoleh dari guru matapelajaran Geografi dapat diketahui bahwa hasil belajar 40% dan keaktifan 24%. Keaktifan yang rendah disebabkan oleh: 1) Siswa tidak memberikan pertanyaan ataupun pendapat pada saat guru memberikan kesempatan untuk bertanya; 2) siswa kurang percaya diri pada saat mempresentasikan Hasil diskusi didepan kelas; 3) Siswa jarang berargumen pada saat diskusi kelompok; 4) Rasa keingintauan siswa rendah, hal ini juga mempengaruhi hasil belajar yang rendah. Hasil observasi dilakukan melalui observasi di kelas X IPS SMA Taman Madya Malang, dengan jumlah 20 siswa. Berdasarkan observasi Hasil Belajar siswa dari 20 siswa hanya 8 siswa yang mecapai KKM dan 12 siswa yang lain tidak mencapai KKM. KKM yang ditetapkan di SMA Taman Madya Malang adalah 75. Sedangkan pada observasi Keaktifan Belajar, dari 20 siswa 11 siswa saja yang aktif dan 9 siswa lainnya tidak aktif. Rancangan penelitian ini menggunakan penelitian tindakan kelas model Kemmis dan Taggard. Penelitian dilakukan di SMA Taman Madya Malang siswa kelas X IPS, yang terdiri dari 20 siswa yaitu 18 laki-laki dan 2 perempuan. Nilai hasil belajar siswa kelas X IPS pada siklus I menunjukan dari 20 siswa yang tuntas 13 orang dengan presentase 65%, dan nilai keaktifan belajar dengan presentase 73%. Sedangkan nilai hasil belajar siklus II menunjukan siswa yang tuntas 17 orang dengan presentase 85%, dan nilai keaktifan belajar siswa dengan presentase 96%. Hasil penelitian dan pembahasan dapat ditarik kesimpulan bahwa penerapan model pembelajaran Kooperatif Time Token dapat meningkatkan hasil belajar dan keaktifan siswa kelas X IPS SMA Taman Madya Malang.
Nilai Laju Pelarutan Batu Gamping Pada Mataair Sumber Agung Di Kecamatan Sumbermanjing Wetan Kabupaten Malang Nilai Laju Pelarutan Batu Gamping Pada Mataair Sumber Agung Di Kecamatan Sumbermanjing Wetan Kabupaten Malang
Authors: Susanti Nelya Eka , Meviana Ika 
Published: August 2019

Kabupaten Malang. Bagian selatan Kabupaten Malang merupakan perbukitan kapur (Karst Malang Selatan) pada ketinggian 0-650 mdpl. Bagian utara merupakan daerah lereng Arjuno-Tengger yang berada pada ketinggian 600-2700 mdpl, bagian timur merupakan daerah lereng Tengger-Semeru, membujur dari utara ke selatan pada ketinggian 500-3600 mdpl, dan bagian barat merupakan daerah lereng Kawi-Arjuno, terdapat pada ketinggian 500-3.300 mdpl. Tujuan penelitian ini menganalisis variasi temporal laju pelarutan batugamping pada mataair sampel dikawasan Karst Malang Selatan. Jenis penelitian ini adalah survei. Populasi penelitian ini adalah seluruh mataair yang berada pada kawasan Karst Malang Selatan, sedangkan sampel penelitian ini adalah mataair yang terletak di Kecamatan Sumbermanjing Wetan. Pengambilan data lapangan untuk variabilitas spasial dan temporal pada mataair mengacu pada periode sampling mingguan yang dilakukan dengan interval waktu dua minggu selama 6 bulan. Hal tersebut dilakukan untuk mengetahui fluktuasi dan perubahan material yang terlarut. Data hasil pengukuran dilakukan analisis variabilitas HCO3- dan analisis laju pelarutan sehingga dapat diketahui beberapa aspek yang berpengaruh terhadap hasil penelitian. Berdasarkan hasil penelitian, diperoleh nilai konsentrasi HCO3- terlarut tahunan tertinggi yang terdapat pada mataair Sumber Agung terjadi pada saat musim kemarau, sebesar 609,71 mg/l. Sedangkan konsentrasi HCO3- terlarut terendah yang terdapat pada mataair Sumber Agung terjadi pada saat musim penghujan, yakni sebesar 531,72 mg/l.
Modal Sosial Dalam Pengelolaan Hutan Produksi Pada Lembaga Masyarakat Desa Hutan (LMDH) Desa Pandantoyo Kabupaten Kediri
Authors: Romzy Naufal , Triwahyudianto Triwahyudianto , Wardani Nila Restu 
Published: August 2019

Abstrak:Hutan produksi merupakan kawasan hutan yang dimanfaatkan untuk memproduksi hasil hutan yangkegiatannya terdiri dari pemanenan, penanaman, pengamanan, pengolahan dan pemasaran hasil kayu di hutan produksi. Modal sosial adalah kemampuan masyarakat untuk bekerjasama demi mencapai suatu tujuan bersama di dalam suatu kelompok. Modal sosial memiliki peran yang signifikan terhadap pembangunan, khususnya terhadap pembangunan berkelanjutan karena modal sosial merupakan salah satu cara mencapai kemajuan bersama. Penelitian ini bertujuan untuk mengetahui tiga unsur modal sosial yaitu kepercayaan (trust), jaringan sosial (network) dan norma (norms) yang terjalin antara Perum Perhutani RPH Pandantoyo, LMDH PHS dan Masyarakat Desa Hutan. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Metode yang digunakan yaitu observasi, wawancara dan dokumentasi. Adapun informan yang dijadikan sebagai narasumber adalah Kepala Perum Perhutani, Ketua LMDH PHS dan Pesanggem (petani yang menggarap lahan hutan milik Perhutani). Teknik analisis data menggunakan wawancara dan dokumentasi, kemudian data diolah sesuai dengan fokus penelitian sehingga ditemukan temuan data. Hasil penelitian menunjukkan bahwa modal sosial di dalam pengelolaan hutan produksi terjalin baik karena tingginya rasa kepedulian diantara Perum Perhutani RPH Pandantoyo, LMDH PHS dan masyarakat yang mengelola hutan. Perum Perhutani dan LMDH meyakini bahwa dengan bekerjasama dengan masyarakat akan memberikan manfaat yang baik dari segi ekologi maupun ekonomi. Tanpa adanya modal sosial yang dianut oleh masyarakat maka kerjasama mereka dengan pihak yang Perhutani dan LMDH dalam mengelola hutan produksi tidak akan bertahan hingga sekarang. Diharapkan masyarakat maupun stakeholder yang terkait dalam pengelolaan hutan yang terjalin saat ini mampu dipertahankan dalam pengelolaan hutan produksi kedepan lebih baik lagi.
Kata kunci:Hutan produksi, modal sosial, LMDH
Sexual assertiveness in women with and without substance-dependent husbands: A comparative study
Authors: Haghparast Zeinab , Riazi Hedyeh , Shams Jamal , Ahmadi Farzane 
Published: August 2019

Abstract
Background

Sexual assertiveness is one of the main issues in sexual relationship between couples. Since substance dependence might disrupt this relationship the present study was designed and conducted to assess and compare sexual assertiveness in women with and without substance-dependent husbands

Methods

This was a cross-sectional study. The Hurlbert Index of Sexual Assertiveness (HISA) was used. The data then were compared between women with and without substance-dependent husbands.

Results

In all 300 women with and without substance-dependent husbands entered into the study. The mean age of the women was 37.31±8.79 and 32.70±7.24 years, and the mean duration of their marriage was 15.92±9.40 and 12.08±8.92 years, respectively. The majority of women with substance-dependent husbands had primary education (40.3%) and the majority of those with non-substance-dependent husbands had higher (37.3%). The mean score of sexual assertiveness was 50.66±14.31 in the women with substance-dependent husbands and 58.42±13.86 in those with non-substance-dependent husbands (P<0.001).

Conclusions

The risk of lower assertiveness for women with substance-dependent husbands was 2.2 times more than women with non-substance-dependent husbands. The husband’s substance dependency is therefore an issue that is worthy of attention in sexual and marital counseling. Sexual assertiveness can be improved in women with substance-dependent husbands through the implementation of appropriate interventions, such as educational and counseling programs.
Predictive value of neutrophil-to-lymphocyte ratio in diagnosis of early prostate cancer among men who underwent Robotic transperineal prostate biopsy
Authors: Jingzeng Du , Lim Ee Jean , Huang Hong Hong , Lau Weber Kam On 
Published: August 2019

Abstract
Background：
NLR is known to have prognostic value for metastatic prostate cancer. However for early-localized prostate cancer due to lack of systemic response; the role of NLR is not conclusive. In this study we aim to evaluate the predictive value of NLR for early clinical indolent prostate cancer in patients who underwent robotic transperineal prostate biopsy (RTPB).

Methods:
Patients who underwent RTPB under general anesthesia, at Urology Department, Singapore General Hospital between Sep 2006 and Feb 2016 were retrospectively reviewed.

NLR was calculated for all patients using full blood count (FBC) that was done as pre-admission test before GA within 4 weeks before operation. And NLR values were compared between prostate cancer (PCa) and benign group.

Results:
A total 652 patients who underwent RTPB for diagnostic purpose with valid PSA level were included in this study. There were total 409 (62.7%) benign histology and 243 (37.3%) prostate cancer. There was no significant difference of median NLR between benign and prostate cancer group (2.00 vs. 1.99; P=0.29).

In the subgroups analysis, there were also no significant difference of median NLR value in clinical significant cancer (defined as Gleason 3 + 4 and above) and benign histology group (NLR 2.00 vs. 2.01, P=0.41), as well as prostate cancer and benign group according to different pre-biopsy PSA levels: PSA (ug/l) < 4, 4-10,10-20 and > 20, respectively. (Median NLR 1.34 vs. 1.76; 1.97 vs. 1.97; 1.97 vs. 2.18; 2.18 vs. 1.98, P>0.05)

Conclusion:
There were no statistical significant difference of NLR between benign and prostate cancer group as a whole or in the subgroup analyses for patients who underwent robotic transperineal prostate biopsy. NLR may have a limited role in predicting early stage prostate cancer.
PCK2:A potential Therapeutic Target and Biomarker for Hepatocellular Carcinoma Based on Weighted Gene Co-Expression Network Analysis
Authors: Wu Jiacheng , Yao Xiaoxiao , Xiang Yien , Qu Xianzhi , Liu Shui , Zhang Xuewen 
Published: August 2019

Abstract
Background

Hepatocellular carcinoma(HCC) is the sixth most common cancer worldwide, and is associated with a high mortality rate and poor treatment efficacy. Therefore, it is important to explore the underlying mechanisms and screen for novel biomarkers and therapeutic targets.

Methods

HCC and non-tumor microarray data was obtained from the Gene Expression Omnibus(GEO) database and 1,612 differentially expressed genes (DEGs) were identified. The identified DEGs were then further examined using a weighted gene co-expression network analysis (WGCNA). Modules were identified and correlations with clinical parameters were examined to ultimately identify a single highly correlated module containing a single hub gene, phosphoenolpyruvate carboxykinase 2 (PCK2).The genes co-expressed with PCK2 were then examined via Gene Ontology(GO) analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis and were found to be primarily enriched in the area of energy metabolism. The association between PCK2 expression and prognosis and tumor stage was then further verified by using a HCC dataset obtained from The Cancer Genome Atlas (TCGA) database. Ex vivo examination of HCC and adjacent non-tumor samples via quantitative real-time PCR demonstrated that PCK2 is downregulated in HCC. Additionally, HCC cell lines overexpressing PCK2 exhibited a time-dependent reduction in cellular viability.

Results

These findings demonstrate that PCK2 is downregulated in HCC and is associated with HCC prognosis and tumorstage, and that PCK2 may affect HCC progression via energy metabolism.

Conclusions

this study may help to further elucidate possible HCC progression mechanisms and the findings presented here suggest that PCK2 may serve as a potential HCC therapeutic target or biomarker.
EPIDEMIOLOGY OF TRAUMATIC DENTAL INJURIES AMONG ADULTS IN AN INDIAN SUB-POPULATION
Authors: RAMACHANDRAN Anupama , KHAN Sulthan Ibrahim Raja , Baskaradoss Jagan 
Published: August 2019

Abstract
Background

The etiology, presentation and management of traumatic dental injuries (TDI’s) varies significantly between the adult and the younger population. Most epidemiological studies on TDI’s have focused on the pediatric age group. This study aims to report and compare the distributions of TDI’s among adults in a sub-population in India.

Methods

This prospective observational study was performed on 1562 consecutively selected patients (1218 Males and 344 females) from a University dental hospital in India, between July 2014 to June 2018. The clinical examinations were performed by a single trained and calibrated Endodontist. Only TDI’s to anterior teeth were recorded (canine to canine in the maxilla and mandible) and classified using a modified version of the WHO’s classification. Intraoral periapical and panoramic radiographs were also taken for all the subjects.

Result

A total of 1562 patients aged between 20 and 73 years, with a mean age of 36 years were examined during the study period. The total number of teeth with TDI’s were 3044. Males (78%) clearly outnumbered the females (22%) in all the age groups. The most common type of injury occurring in both the genders is uncomplicated crown fracture. Avulsion injuries are more likely to be seen by a dentist within 1hour post-trauma. About two third of the TDI’s were caused by road traffic accidents (RTA) followed by falls in about 20% of the patients.

Conclusion

Uncomplicated crown fracture was the most commonly observed type of TDI and RTA’s were the primary cause of TDI.
Anthropometric surrogates of Birth weight reproducible by Community Health Workers: A hospital-based cross sectional study at Mbarara Regional Referral Hospital, South Western Uganda
Authors: Ayesiga Savino , Abaasa Catherine , Ayebare David , Wamuyu-Maina Gakenia 
Published: August 2019

Abstract
Background

In many resource constrained countries Uganda inclusive, women continue to give birth from home/in the community where there are no weighing scales to measure and record birth weight. There is also lack of enough weighing scales and skilled health personnel at health facility level to ensure that birth weight for every child is timely determined. Birth weight is an indicator of the chances for survival, growth, long-term health and psychosocial development of neonates. Different anthropometric parameters are reliable surrogates of birth weight although they are highly contextual. This study assessed the best anthropometric surrogate of birth weight usable at facility and community levels in western Uganda.

Methods

A cross sectional study was conducted between July and September 2017, whereby anthropometric values of 553 neonates born at Mbarara Regional Referral Hospital were measured by two midwives and later repeated by two community health workers to determine the reproducibility. Data regarding birth weight, height, foot length and circumference of head, mid upper arm, chest, thigh and calf were collected and recorded. Frequencies, percentages and mean and standard deviation were used to describe categorical and continuous demographics of neonates respectively. Pearson correlations, specificity, sensitivity, likelihood ratios, diagnostic odds ratios and area under the curve (AUC) were determined and used to establish the most reliable anthropometric parameter that best estimates birth weight of neonates.

Results

Chest Circumference was the most reliable parameter (AUC= 0.89, DOR= 33.57). There were statistical significant mean differences in all the anthropometric measurements made by midwives and CHWs except for chest circumference (Mean difference = 0.03 cm, 95% CI: -0.22-0.29, p = 0.7963) and foot length (Mean difference = 0.03 cm, 95% CI: -0.22-0.29, p = 0.7963).

Conclusions

Chest circumference taken within 24 hours after birth is the best nthropometricsurrogate measure of birthweight. Community Health workers can measure chest circumference with almost the same accuracy like midwives.
Urbanisation, climate change and its impact on water quality and economic risks in a water scarce and rapidly urbanising catchment: case study of the Berg River Catchment
Authors: Cullis James D. S. , Horn Annabel , Rossouw Nico , Fisher-Jeffes Lloyd , Kunneke Marlé M. , Hoffman Willem 
Published: August 2019

Abstract
By 2050 it is predicted that 67% of the world population is expected to be living in urban areas, with the most rapid levels of urbanisation taking place in developing countries. Urbanisation is often directly linked to the degradation of environmental quality, including quality of water, air and noise. Concurrently, the climate is changing. Together, the negative impacts of climate change and urbanisation pose significant challenges, especially in developing countries where resources to mitigate these impacts are limited. Focusing on the Berg River Catchment in South Africa, which is experiencing increasing levels of urbanisation, the impacts of climate change, the ‘wicked problem’ of service delivery to the historically disadvantaged within a developing country, persistent infrastructure backlogs, and where high unemployment is prevalent, this paper explores the increasing water quality risks due to climate change and rapid urban development and the likely direct and indirect economic impacts that this will have on the agriculture sector, which is a key contributor to the regional and national economy. The results give support to the need to invest in risk mitigation measures including the provision of basic services, the upgrading and maintenance of wastewater treatment plants and investing in ecological infrastructure.