bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is end-organ surveillance necessary in patients with well-functioning metal-on-metal hip resurfacings?
Authors: Juneau D. , Grammatopoulos G. , Alzahrani A. , Thornhill R. , Inacio J. R. , Dick A. , Vogel K. I. , Dobransky J. , Beaulé P. E. , Dwivedi G. 
Published: April 2019

Aims Cardiac magnetic resonance (CMR) was used to assess whether cardiac function or tissue composition was affected in patients with well-functioning metal-on-metal hip resurfacing arthroplasties (MoMHRA) when compared with a group of controls, and to assess if metal ion levels correlated with any of the functional or structural parameters studied. Patients and Methods In all, 30 participants with no significant cardiac history were enrolled: 20 patients with well-functioning MoMHRA at mean follow-up of 8.3 years post-procedure (ten unilateral, ten bilateral; 17 men, three women) and a case-matched control group of ten non-MoM total hip arthroplasty patients (six men, four women). The mean age of the whole cohort (study group and controls) at the time of surgery was 50.6 years (41.0 to 64.0). Serum levels of cobalt and chromium were measured, and all patients underwent CMR imaging, including cine, T2* measurements, T1 and T2 mapping, late gadolinium enhancement, and strain measurements. Results None of the MoMHRA patients showed clinically significant cardiac functional abnormality. The MoMHRA patients had larger indexed right and left end diastolic volumes (left ventricular (LV): 74 ml/m2 vs 67 ml/m2, p = 0.045; right ventricular: 80 ml/m2 vs 71 ml/m2, p = 0.02). There was a small decrease in T2 time in the MoMHRA patients (median 49 ms vs 54 ms; p = 0.0003). Higher metal ion levels were associated with larger LV volumes and with shorter T2 time. Conclusion Although cardiac function is not clinically adversely affected in patients with well-functioning MoMHRA, modern imaging is able to demonstrate subtle changes in structure and function of the heart. As these changes correlate with systemic ion measurements, they may be consequences of wear debris deposition. Longer, longitudinal studies are necessary to determine whether cardiac function will become affected. Cite this article: Bone Joint J 2019;101-B:540–546.
Heuristic Methodology for Forecasting of Production in Waste Management
Authors: Smejkalova Veronika , Somplak Radovan , Nevrly Vlastimir 
Published: April 2019

The forecast of waste production and disposal is an important requirement for a future waste management planning. The problem is very often a short time series of the database. This paper suggests an approach to forecast the production of multiple waste types in micro-regions taking into account this challenge by combining many techniques. The heuristic methodology consisting of few steps is formulated. First, the input data are transformed and the methods from cluster analysis are repetitively applied. The second step is about a determination of quality for trend functions based on historical data. In the last step is performed the testing. The di erent type of representatives from cluster analysis is used to calculate indices of determination which are compared. This procedure is repeated until the criteria hit. The proposed approach reduced the computational time and managed to aggregate micro-regions with a similar trend. The forecast should have contributions in terms of building new facilities or adaptations to the existing ones, where it is necessary to estimate the production of waste for several years in advance. The article includes a case study of production forecast for several waste types in territorial units of the Czech Republic. The forecast is based on data in years 2009{2014 and following year 2015 was used to assess the quality of the nal models. In the future, the database will expand and thus it will be possible to make more precise estimates and to develop statistical methods to measure this prognostic tool.
Two-Degree-of-Freedom Controller Tuning
Authors: Lang Stanislav , Matousek Radomil , Svarc Ivan 
Published: April 2019

Two-degree-of-freedom controllers have the ability to affect the dynamics of a system when the reference value changes. The answer to the question of parameter tuning for this additional lter still remains unclear we describe a new method for the design of said controller. We compare the behaviour of the controllers designed using the presented method versus the classic method on several instances.
Emotional Awareness and Alexithymia in Smokers Seeking Help for Cessation: A Clinical Analysis
Authors: Carton Solange , Bayard Sophie , Jouanne Céline , Lagrue Gilbert 
Published: April 2019

AbstractThe construct of emotional awareness refers to attending to, identifying, differentiating, and labelling emotions in oneself and in others. Forty-two smokers were evaluated before they stopped smoking and also filled out the Levels of Emotional Awareness Scale (LEAS), the Toronto Alexithymia Scale (TAS-20), and the Sensation Seeking Scale (SSS). Subjects had low levels of emotional awareness and their scores on the emotional components of the TAS-20 were high in comparison to the general French population. No relationship was found between TAS-20 and LEAS, which confirms that these scales measure complementary dimensions of emotional processing that are only partially linked. Whereas sensation seeking was lower in self-rated alexithymic subjects, high scores on Boredom Susceptibility and total SSS among women were related to low LEAS scores. The results highlighted impairment of emotion processing in these subjects. Their state versus trait status is discussed, as well as their defensive functions. Treatment targeting emotional abilities enhancement for these subjects, as in other addictions, may help improve treatment of tobacco dependence.
STUDI IMPLEMENTASI KEBIJAKAN DESENTRALISASI ADMINISTRATIF DI MUNICIPIO DILI TIMOR-LESTE
Authors: Joniarta I Wayan , Sucitawathi P I.G.A.AG Dewi , Soares Inácio , Suderana Wayan 
Published: April 2019

This research aims to empirically elaborate the implementation of administrative decentralization in Municipio Dili Timor-Leste. This research scrutinizes human resource, financial resource, facilities and implementing structure in bureaucracy to identify implementation effectiveness. This research applies qualitative methods using interviews as methods for collecting data, observation and document reviews. This research found that the implementation of administrative decentralization has not yet been effective. There is a need for capacity building to improve government officers' capability to better off the quality of public service.
First spatial distribution of potentially toxic benthic dinoflagellates in the Lesser Antilles (Guadeloupe and Martinique), Caribbean Sea
Authors: Boisnoir Aurélie , Pascal Pierre-Yves , Marro Sophie , Lémée Rodolphe 
Published: April 2019

Abstract
For the first time, distribution and abundances (cells per gram of fresh macrophyte weight) of potentially toxic benthic dinoflagellates were studied around Guadeloupe (20 sites) and Martinique (six sites) islands (Lesser Antilles, Caribbean Sea). Benthic dinoflagellates were identified at the genus level and cell counts were undertaken on different host species of macroalgae and seagrasses. Abundance values of potentially toxic benthic dinoflagellates were one order of magnitude higher in Guadeloupe than in Martinique. The highest abundances of benthic dinoflagellates were found in the northern part of Guadeloupe Island, while their distribution was more homogeneous in Martinique. Ostreopsis was the dominant genus in Guadeloupe and Martinique. Regarding biotic substrate preferences, Phaeophyceae hosted the highest total abundances of benthic dinoflagellates on both islands, while the lowest total abundances were observed on Ulvophyceae in Guadeloupe and Florideophyceae in Martinique. The genus Gambierdiscus, known as the causal agent of the ciguatera fish poisoning (CFP), developed on all macrophyte groups on both islands without showing any preferences towards biotic substrates. The presence of this potentially harmful dinoflagellate genus in both islands could explain the existence of local cases of CFP in Guadeloupe and Martinique islands.
Effects of Azadirachta Indica Leaf Extract, Capping Agents, on the Synthesis of Pure And Cu Doped ZnO-Nanoparticles: A Green Approach and Microbial Activity
Authors: Handago Dawit Tamire , Zereffa Enyew Amare , Gonfa Bedasa Abdisa 
Published: April 2019

AbstractThe current studies presented the green synthesis of zinc oxide and copper doped ZnO nanoparticles (NPs) using different ratios of Neem leaf extract and its antibacterial application on drug-resistant bacteria. The synthesized NPs were characterized using: X-ray diffractions (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscope (SEM), UV–visible spectroscopy and a simultaneous DTA-TGA thermal analyzer. All the synthesized materials were stable above 400°C. The powder diffraction studies indicated the formation of phase pure materials with wurtzite structure for pure ZnO and 0.5%, 1%, 1.5% Cu doped ZnO with the crystallite size in the range of 16.07 – 23.74 nm. SEM analysis revealed the formation of spherical shaped NPs with large grain size for 10% (v/v) ratio of aqueous leave extract. The aqueous extract of neem act as capping agent and prevent the NPs from agglomeration. The spectral studies confirmed the formation of NPs with the absorbance peak that is different from the micro-size ZnO. The antibacterial activities of the synthesized materials ZnO (1:1) against Staphylococcus aureus and uncalcined ZnO (7:3) and (Zn0.985Cu0.015O) against Bacillus subtilis were enhanced when referenced to the standard gentamicin.
Tunable Brillouin and Raman microlasers using hybrid microbottle resonators
Authors: Zhu Song , Xiao Bowen , Jiang Bo , Shi Lei , Zhang Xinliang 
Published: April 2019

Abstract
We realized a tunable Brillouin laser and a tunable Raman laser by using ultrahigh-quality-factor (Q) hybrid microbottle resonators. The whispering-gallery-mode microresonator-based Brillouin and Raman lasers possess unique advantages (e.g. low threshold, narrow line width, and flexible lasing wavelength region) and various potential applications. Efficient tuning of the Brillouin and Raman microresonator lasers is desirable in many cases. However, the corresponding lasing wavelength tunability is rarely reported. In this work, we realized the ultralow-threshold Brillouin and Raman lasers based on the proposed hybrid microbottle resonators with Q factors over 108. Meanwhile, by feeding the control light through the axial direction of the hybrid microbottle resonators, a Brillouin lasing wavelength tuning range of 2.68 nm and a Raman lasing wavelength tuning range of 2.32 nm are realized, which are one order of magnitude and almost once larger than those reported in the previous works, respectively. Such tunable microlasers could find significant applications in light sources, microwave photonics, and optical sensing.
From “Cuines del Món” Gastronomic BiblioLab to “Cuinem Santa Coloma”: Cooking cultures and social cohesion at Fondo Public Library (Santa Coloma de Gramenet, Barcelona)
Authors: Chavarria Domingo Mariona 
Published: April 2019

AbstractThis communication presents a library service carried out at the Library of Fondo, Santa Coloma de Gramenet. Cuines del Món, a gastronomic BiblioLab, is part of the BiblioLab programme of the MLN at Barcelona province (Catalonia). Cuines del Món starts from an analysis of the surrounding area of the library, a highly intercultural one, and with some associated problems like a high poverty index. Cuines del Món is about gastronomy and cooking but, above all, is about community building, interculturality in view. The aim is to offer a space, a completely equipped kitchen, and related cultural activities, which provide a positive interaction working on common interests producing active and collaborative relationships between people and groups which normally would not establish contact, establishing mechanisms or resources to achieve a culturally diverse participation in its activities, by recognising diversity, promoting the knowledge and the visibility of cultural diversity, and implementing measures to ensure equity, egalitarian access to information and culture, rights, opportunities to people issued from diverse cultural and social origins and avoiding discrimination. All this with an active involvement of citizens.
Senior Sway: Using a Mobile Application to Measure Fall Risk
Authors: Pergolotti Mackenzi , Deal Allison M. , Bryant Ashley L. , Bennett Antonia V. , Farley Erica , Covington Kelley , Lucas Katie , Williams Grant R. 
Published: April 2019

Background and Purpose:
The Senior Sway mobile application uses the iPhone/iPad gyroscope to assess postural sway and motion reaction time. Impairment in postural sway and motion reaction time have the potential to increase risk for future falls. Senior Sway thereby has the potential to provide a quick, easy to use, objective measure for predicting falls in older adults. The purpose of this study was to evaluate the feasibility of the Senior Sway mobile application and its associations with fall risk in community-dwelling older adults.

Methods:
Adults older than 62 years were recruited from senior centers and community events. Descriptive and bivariate statistics were used to examine feasibility on the basis of enrollment, time required, satisfaction with application, and association with fall risk.

Results and Discussion:
Fifty-seven adults were recruited. Use of the Senior Sway mobile application was feasible. Ninety-one percent said that they liked the application and reported length of time of assessment was “just right.” The average Senior Sway score was 64.0 (range: 47.8-84.0), which was significantly associated with the 30-second sit-to-stand test. In addition, the motor reaction time score was associated with the Timed Up and Go.

Conclusions:
Senior Sway is a promising application to improve identification of adults at risk for falls and need for rehabilitation but warrants further research.
A herediter haemorrhagiás teleangiectasia (Osler–Weber–Rendu-kór) genetikai diagnosztikája
Authors: Major Tamás , Gindele Réka , Szabó Zsuzsanna , Jóni Natália , Kis Zsuzsanna , Bora László , Bárdossy Péter , Rácz Tamás , Karosi Tamás , Bereczky Zsuzsanna 
Published: April 2019

Abstract: Introduction: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant multisystemic vascular disease with a worldwide prevalence of 1 : 5000 – 1 : 10 000. Diagnosis is based on clinical Curacao criteria. Approximately 85% of HHT cases have heterozygous family-specific mutations in the ENG or ACVRL1 genes. Aim: We investigated 23 Hungarian HHT families, established the genetic diagnosis, executed family-screening and confirmed founder effects. Method: Probands were identified by the stratified population screening of the primary attendance area of our institution and from individuals contacting our study group voluntarily. Diagnosis is based on the otorhinolaryngological physical examination completed with characteristic telangiectasis sites, a visceral arteriovenous malformation screening and the sequence analysis of ENG and ACVRL1 genes. The family screening consists of physical examination and genetic screening for the family-specific mutation, followed by the arteriovenous malformation screening in patients with definite/suspected HHT and/or in individuals with the mutation. Results: Sixty-three individuals with family-specific mutations were identified in 22 families, 48 of them with definite and 12 with suspected HHT. Seven ENG and ACVRL1 mutations were detected, respectively; most of these are pathogenic. Three founder mutations were observed. One proband with definite HHT had wild-type alleles in all tested HHT-specific loci. Conclusions: The significance of genetic testing is confirming or excluding HHT in young asymptomatic individuals in families with pathogenic mutations. As ENG and ACVRL1 mutations result in overlapping fenotypes, the genetic testing lacks any prognostic value. The identification of founder effects might simplify the genetic diagnosis of new HHT patients from a given region. Orv Hetil. 2019; 160(18): 710–719.
Evelyn Underhill rozumienie mistyki
Authors: Kiwka Mirosław 
Published: April 2019

W świecie anglojęzycznym I połowy XX wieku Evelyn Underhill (1875–1941) była jedną z najbardziej poczytnych autorek, piszących o religii i życiu duchowym, a szczególnie o mistyce chrześcijańskiej. Ukazanie zasadniczych elementów jej teorii mistyki stanowi zasadniczy cel niniejszego przedłożenia. Jego realizację otwiera przedstawienie wypracowanego przez nią pojęcia mistyki i jej zasadniczych charakterystyk. Omówienie etapów procesu mistycznego, problemu autentyczności oraz jedności doświadczenia mistycznego łącznie z kontekstem filozoficznym i strukturami antropologicznymi, które autorka wykorzystuje w swoich analizach – stanowi tematykę dalszej części opracowania. Całość zamyka niezwykle inspirująca wizja mistycznej przyszłości rodzaju ludzkiego, jaką znajdujemy w publikacjach tej anglikańskiej pisarki.
Wolność a łaska. Interpretacja problemu w filozofii Józefa Tischnera
Authors: Trombik Kamil 
Published: April 2019

W artykule podjęto próbę rekonstrukcji poglądów Józefa Tischnera dotyczących zagadnienia relacji między łaską a wolnością człowieka. Omówiony został także filozoficzno-teologiczny kontekst, w ramach którego kształtowały się poglądy krakowskiego myśliciela. Wskazano również na najbardziej perspektywiczne wątki w Tischnerowskiej koncepcji łaski i wolności, które mogą okazać się inspirujące zarówno w obrębie dyscyplin filozoficznych, jak i teologicznych.
Przez wsparcie do jakości kształcenia. O sytuacji osób z niepełnosprawnościami w UPJPII w Krakowie
Authors: Bolińska Marta 
Published: April 2019

Od kilku lat w Polsce zainteresowanie sytuacją osób niepełnosprawnych rośnie. Zmiany w szkolnictwie wyższym obejmują także kandydatów na studentów i studentów z niepełnosprawnością. O ile infrastruktura działa coraz lepiej, o tyle zarówno nauczyciele akademiccy, jak i administracja mają jeszcze wiele do zrobienia. Stopniowo zwiększa się jednak świadomość, że niepełnosprawność nie musi być ograniczeniem, także w dostępie do nauki na uczelni wyższej. Uniwersytety dążą do tego, aby studenci mieli jednakowe szanse na kształcenie i nie doświadczali ograniczeń w uczestniczeniu w życiu społeczności akademickiej np. z powodu niepełnosprawności.
Sodium intercalation into α- and β-VOSO4
Authors: Deriouche W. , Anger E. , Amdouni N. , Pralong V. 
Published: April 2019

Na-ion battery is one of the best alternatives to Li-ion battery. Abundance of sodium on earth is three orders of magnitude higher than lithium, which should make Na-ion battery technology cheaper. But alkaline-ion battery prices, which tend to increase because of the massive world demand, also depend on the choice of electrode materials. Therefore, cost-effective electrode development remains an important subject of research because this will allow Na-ion battery to be even more competitive. Electrochemical performances of anhydrous VOSO4 as electrode for Na-ion battery are reported in this letter. Two anhydrous phases of vanadyl sulfate have been studied. The first one, α-VOSO4, shows that up to 0.8 sodium per formula unit (Na/f.u.) can be intercalated in this phase, and a reversible intercalation of 0.4 Na/f.u. has been observed with a strong polarization. The second one, β-VOSO4, can intercalate up to 0.9 Na/f.u. with a reversible intercalation of 0.4 Na/f.u. leading to a reversible capacity of 64 mAh/g.
Phase II Study of S-1 and Paclitaxel Combination Therapy in Patients with Previously Treated Non-Small Cell Lung Cancer
Authors: Chihara Yusuke , Yoshimura Akihiro , Date Koji , Takemura Yoshizumi , Tamiya Nobuyo , Kohno Yoshihito , Imabayashi Tatsuya , Takeuchi Mayumi , Kaneko Yoshiko , Yamada Tadaaki , Ueda Mikio , Arimoto Taichiro , Uchino Junji , Iwasaki Yoshinobu , Takayama Koichi 
Published: April 2019

Abstract

Lessons Learned
In terms of efficacy and safety, good results were obtained with S-1 and paclitaxel (PTX) combination therapy. The findings suggest that S-1 and PTX combination therapy is a feasible treatment option in patients with previously treated non-small cell lung cancer.

Background
Although monotherapy with cytotoxic agents, including docetaxel and pemetrexed, is recommended for patients with previously treated advanced non-small cell lung cancer (NSCLC), its outcomes are unsatisfactory. S-1 is an oral fluoropyrimidine agent that consists of tegafur, 5- chloro-2, 4-dihydroxypyridine, and potassium oxonate. S-1 is approved for patients with gastric cancer in 7 Asian countries and 15 European countries. It is also approved for patients with eight type of cancers, including NSCLC, in Japan. We evaluated the efficacy and toxicity of S-1 and paclitaxel (PTX) combination therapy in patients with previously treated NSCLC.

Methods
Oral S-1 was administered thrice weekly on days 1–14 at 80, 100, and 120 mg/day in patients with body surface areas of &lt;1.25, 1.25–1.5, and &gt;1.5 m2, respectively. PTX was administered at 80 mg/m2 on days 1 and 8. Primary endpoint was response rate, and secondary endpoints were progression-free survival (PFS), overall survival (OS), and safety.

Results
Forty patients were enrolled, with response and disease control rates of 27.5% and 75.0%, respectively (Fig. 1). Median PFS and OS were 6.5 and 20.7 months, respectively. Grade 3/4 anemia and thrombocytopenia were seen in five (12%) and one (2%) patients, respectively. Febrile neutropenia occurred in three patients (7%). Common grade 3/4 nonhematological toxicities were stomatitis (5% of patients), diarrhea (7% of patients), and interstitial lung disease (one patient). No treatment-related deaths were observed.

Conclusion
This S-1 and PTX cotherapy dose and schedule showed satisfactory efficacy, with mild toxicities, in patients with previously treated advanced NSCLC.
Mitigation of ancient coal mining hazards to overhead line equipment structures
Authors: Haiderali Aliasger E. 
Published: April 2019

Subsidence and collapse of structures supporting overhead line equipment (OLE) due to legacy coal mining can be catastrophic during both the construction and operational phases, causing damage to construction plant, injuries and fatalities to the construction and maintenance workforce, failure of the track and disruption to the operational railway. When applied to linear railway schemes spanning considerable distances, industry guidelines for appraising and mitigating these mining hazards are overly conservative with a disproportionate cost. On phase 4 of the North West Electrification Project between Manchester Victoria and Euxton Junction, an innovative risk-based method was devised and implemented to identify and mitigate mining hazards to OLE structures. Formulation of these value-engineering solutions prevented programme drift and led to significant cost savings. Details of this methodology, including a detailed desk study, computational geomechanics, a well-targeted ground investigation, void remediation and real-time foundation monitoring, are discussed in this paper.