bluuebunny/crossref_metadata_2025_split huggingface dataset:
Future Perspective of Diabetic Animal Models
Authors: Pandey Shashank , Dvorakova Magdalena C. 
Published: June 2019

Objective:The need of today’s research is to develop successful and reliable diabetic animal models for understanding the disease susceptibility and pathogenesis. Enormous success of animal models had already been acclaimed for identifying key genetic and environmental factors like Idd loci and effects of microorganisms including the gut microbiota. Furthermore, animal models had also helped in identifying many therapeutic targets and strategies for immune-intervention. In spite of a quite success, we have acknowledged that many of the discovered immunotherapies are working on animals and did not have a significant impact on human. Number of animal models were developed in the past to accelerate drug discovery pipeline. However, due to poor initial screening and assessment on inequivalent animal models, the percentage of drug candidates who succeeded during clinical trials was very low. Therefore, it is essential to bridge this gap between pre-clinical research and clinical trial by validating the existing animal models for consistency.Results and Conclusion:In this review, we have discussed and evaluated the significance of animal models on behalf of published data on PUBMED. Amongst the most popular diabetic animal models, we have selected six animal models (e.g. BioBreeding rat, “LEW IDDM rat”, “Nonobese Diabetic (NOD) mouse”, “STZ RAT”, “LEPR Mouse” and “Zucker Diabetic Fatty (ZDF) rat” and ranked them as per their published literature on PUBMED. Moreover, the vision and brief imagination for developing an advanced and robust diabetic model of 21st century was discussed with the theme of one miceone human concept including organs-on-chips.
Fuzzy Classification Methods Based Diagnosis of Parkinson’s disease from Speech Test Cases
Authors: Dastjerd Niousha Karimi , Sert Onur Can , Ozyer Tansel , Alhajj Reda 
Published: June 2019

Background:
Together with the Alzheimer’s disease, Parkinson’s disease is considTogether with the Alzheimer’s disease, Parkinson’s disease is considered
as one of the two serious known neurodegenerative diseases. Physicians find it hard to
predict whether a given patient has already developed or is expected to develop the Parkinson’s
disease in the future. To overcome this difficulty, it is possible to develop a computing
model, which analyzes the data related to a given patient and predicts with acceptable accuracy
when he/she is anticipated to develop the Parkinson’s disease.ered as one of the
two serious known neurodegenerative diseases. Physicians find it hard to predict whether a given
patient has already developed or is expected to develop the Parkinson’s disease in the future. To
overcome this difficulty, it is possible to develop a computing model, which analyzes the data related
to a given patient and predicts with acceptable accuracy when he/she is anticipated to develop
the Parkinson’s disease. This paper contributes an attractive prediction framework based on some
machine learning approaches. Several fuzzy classifiers have been employed in the process to distinguish
people with Parkinsonism from healthy individuals. The fuzzy classifiers utilized in this
study have been tested using the “Parkinson Speech Dataset with Multiple Types of Sound Recordings
Data Set” available from the UCI repository. The results reported in this paper are better than
the results reported by Sakar et al., where the same dataset was used, but with different classifiers.
This demonstrates the applicability and effectiveness of the fuzzy classifiers used in this study as
compared to the non-fuzzy classifiers used by Sakar et al.

Objectives:
This paper contributes an attractive prediction framework based on some machine
learning approaches for distinguishing people with Parkinsonism from healthy individuals.

Methods:
Several fuzzy classifiers such as Inductive Fuzzy Classifier, Fuzzy Rough Classifier
and two types of neuro-fuzzy classifiers have been employed.

Results:
The fuzzy classifiers utilized in this study have been tested using the “Parkinson
Speech Dataset with Multiple Types of Sound Recordings Data Set” of 40 subjects available
on the UCI repository.

Conclusion:
The results achieved show that FURIA, MLP- Bagging - SGD, genfis2 and scg1
performed the best among the fuzzy rough, WEKA, adaptive neuro-fuzzy and neuro-fuzzy
classifiers, respectively. The worst performance belongs to nearest neighborhood, IBK, genfis3
and scg3 among the formerly mentioned classifiers. The results reported in this paper are better
in comparison to the results reported in Sakar et al., where the same dataset was used, with utilization
of different classifiers. This demonstrates the applicability and effectiveness of the
fuzzy classifiers used in this study as compared to the non-fuzzy classifiers used by Sakar et al.
Herbal Dentifrices: Emerging Trends and Patterns
Authors: Pal Rashmi Saxena , Pal Yogendra , Wal Ankita , Wal Pranay 
Published: June 2019

Background:
Herbal extracts have been employed since ages in dentistry as tooth
cleansing and antimicrobial agents. The use of herbal medicines continues to expand and
trend rapidly across the world. Herbal extracts have been used in dentistry for multiple uses
as reducing inflammation, as antimicrobial plaque agents, for preventing release of histamine
and as antiseptics, antioxidants, antimicrobials and analgesics. They also aid in healing
process and are very effective in controlling microbial plaque and other disorders related to
gums.

Objective:
The present review aims towards the combined review as well as compilation of
available herbs under the category of various dental associated problems.

Materials and Methods:
The herbs were studied by sectioning them as for looking after different
works or findings done against dental caries, tooth ache, scouring teeth, gum troubles
and herbs as mouth fresheners.

Results:
Herbal extracts have been used on a large scale in dentistry as tooth cleansing and
antimicrobial plaque agents. Many people take herbal derived medicines or herbal based
products for the purpose of reducing inflammation, as antimicrobial agents, for preventing
release of histamine and as antiseptics, antioxidants, antifungals, antibacterials, antivirals
and analgesics. Herbal extracts are used in dentistry for treatment of various dental disorders.

Conclusion:
The use of herbal medicines are blooming rapidly across the world. Herbal extracts
and the various herbs on the whole or their specific parts have been used in dentistry.
They relieve the problems of gums and act as excellent mouth fresheners. The natural herbal
remedies act as an effective substitute to antibiotics and represent a promising approach for
prevention and as therapeutic strategies for various oral infections as they are natural, eradicate
the problem from its root and provide long lasting relief. The herbal remedies are advantageous
over conventional treatment.
2.4GHZ AKILLI HABERLEŞME SİSTEMLERİ İÇİN SARMAL ŞEKİLLİ FREKANS SEÇİCİ YÜZEY TASARIMI
Authors: BELEN Mehmet Ali , MAHOUTİ Peyman 
Published: June 2019

Haberleşme
sistemleri günümüz teknolojik gelişmeler ile hızlı bir şekilde ilerlemektedir.
Kullanıcı dostu ve düşük maliyetli olmasıyla, günümüzde kablosuz haberleşme
sistemleri tercih edilmektedir. Kablosuz haberleşme sistemlerinde verimliliğin
arttırılması adına sinyal girişimlerin önlenmesi bir gereklilik haline
gelmiştir. Bu yüzden alıcı sistemlerde anten öncesine yerleştirilen ön
filtreleme elamanları üzerine çalışmalar yoğunlaşmıştır. Özellikle mikrodalga
alanında birçok uygulama frekans seçici yüzey kullanılarak
gerçekleştirilmektedir. Bu çalışmada ISM band frekanslarında, mikroşerit sarmal
şekilli yapı kullanılarak tasarlanmış bir band geçiren frekans seçici yüzey
(FSY) önerilmektedir. Sarmal yapı üzerindeki hat genişlikleri ve boşlukları
değiştirildiğinde çalışma frekansı ve karakteristiği ayarlanabilir bir FSY
önerilmiştir. Yapılan
incelemelerde sonucunda rezonans frekansı 1.8GHz ile 5.2GHz arasında değiştiği
gözlenmiştir. CST-MWS yazılımı
kullanılarak tasarımlar ve spesifikasyonları elde edilmiştir.
Evaluación de la política de transparencia en el Municipio de San Pedro Garza García en el Estado de Nuevo León en México, 2015-2017
Authors: Aguilera Hintelholher Rina Marissa 
Published: June 2019

<p>El presente artículo analiza el desempeño de la política de transparencia en el municipio de San Pedro Garza García, situado en el estado de Nuevo León. Este municipio registra uno de los avances más importantes en materia de desempeño institucional en el periodo 2015-2018, debido a que estimula la política de transparencia, no sólo como una forma de acceder a ella, sino para dar formar al ámbito de datos abiertos que lo califican como una entidad comprometida con demandas ciudadanas que plantean no sólo acceder y conocer lo que realiza, sino por la manera en que se evalúa su desempeño</p>
La construcción de la independencia y del poder de la Suprema Corte de Justicia en México. Explicando la Reforma Judicial de 1994
Authors: Cortez Salinas Josafat , Salazar Rebolledo Grisel 
Published: June 2019

<p>El presente trabajo responde a la pregunta clásica sobre los factores que llevan a construir Cortes independientes y poderosas para intervenir en la vida pública. A diferencia de las variables independientes utilizadas por la literatura: incertidumbre electoral, la composición de la coalición de reforma y la búsqueda de la legitimidad, este trabajo sostiene que la reforma judicial en México de 1994 se explica por los recursos de los actores en el proceso de negociación. Para comprobar este argumento, se toman como referentes empíricos las huellas de los procesos<br />de negociación disponibles en la publicación del Diario de los Debates que documentaron el proceso de reforma</p>
المدخل الاتصالي في تعليم اللغة العربية لغير الناطقين بها
Authors: Ediyani Muhammad 
Published: June 2019

تعتبر اللغة من أهم المعايير التي تقاس بها فاعلية الأمم في مضمار التقدم والحضارة والتأثير والتأثر، ووظيفة الاتصال إحدى أهم وظائف اللغة ذات الطابع الاجتماعي فهي تمثل علاقة اللغة والمجتمع وعلاقة الفرد بالمجتمع من خلال اللغة، فاللغة هي أداة المرء في الاتصال بأفراد المجتمع. وخصائص المدخل الاتصالي من حيث المفاهيم اللغوية إنها نظام للتعبير عن المعنى، والوظيفة الأولى للغة هي تحقيق التفاعل. والخصائص من حيث طبيعة تعليم اللغة وتعلمها قدرة الفرد على تحليل أشكال الحديث والكتابة وفهم السياق الاجتماعي الذي يتم من خلاله الاتصال بما في ذلك العلاقات التي تربط بين الأدوات الاجتماعية المختلفة والقدرة على تبادل المعلومات والمشاركة الاجتماعية بين الفرد والآخرين.
SIBREH البطاقة المقطعة الملونة واستخدامها لترقية قدرة الطلبة على الموازنة بين الجمل الاسمية والفعلية بالمدرسة الثانوية الاسلامية
Authors: Qusaiyen Qusaiyen , Azmi Khairul 
Published: June 2019

إن الموضوع لهذا البحث هو:"البطاقة المقطعة الملونة واستخدامها لترقية قدرة الطلبة على الموازنة بين الجمل الاسمية والفعلية بالمدرسة الثانوية الاسلامية الحكومية MAN ". وقد إختار الباحث هذا الموضوع لأن الطلبة في المدرسة الثانوية الاسلامية الحكومية MAN يتعلمون درس اللغة العربية ويمارسون ويحفظون ذلك الدرس في فصولهم, ولكن أكثرهم لم يقدروا على سيطرة ذلك الدرس جيدا خاصة فى الموضوع الجملة الاسمية والجملة الفعلية. ولذلك، أراد الباحث أن يقدم علاجا لهذه المشكلة, فجرّب الباحث أن يستعمل بالوسائل التعليمية فهي البطاقة المقطعة الملونة. وأما أهداف البحث فهو معرفة قدرة الطلبة باستخدام البطاقة المقطعة الملونة وتطبيقها لترقية قدرة الطلبة على الموازنة بين الجمل الاسمية والفعلية. وأما منهج البحث فهو البحث التجريبي بالتصميمات. وأدوات البحث فهي الاختبار والملاحظة. فالعينة في هذا البحث هو الطلبة صف الثاني.ب وصف الثاني.ج عددهم 56 طالبا. وأما نتائج البحث فهي البطاقة المقطعة الملونة واستخدامها لترقية قدرة الطلبة على الموازنة بين الجمل الاسمية والفعلية. وقد عرف الباحث على نتيجة الاختبار القبلي ونتيجة الاختبار البعدي. ويكون مقبولا، لأن النتيجة “ttest” أكبر من النتيجة “ttable” هي (1,00<1,86).
Estimación de la abundancia de Caiman crocodilus (Crocodilia: Alligatoridae) en Caño Negro, Costa Rica, utilizando el modelo N-mixture
Authors: Aranda-Coello J. Manuel 
Published: June 2019

El tamaño (N) de las poblaciones de cocodrilos rara vez se puede determinar con precisión. Objetivo: comparar la abundancia con recuentos repetidos espacialmente, con el Modelo de N-mezclas y con el Método Messel, usando una población costarricense. Métodos: conté caimanes por la noche a lo largo de 21km del río Frío (Betel-Boga Sabogal). Dividí el tramo en 32 segmentos (500m) separados 200m entre sí. Resultado: el modelo N-mezclas produjo una estimación de 2 162 individuos y el Messel 373. Conclusión: los recuentos repetidos espacialmente y analizados con el modelo N-mezclas, parecen proporcionar datos más confiables.
A Report to the Members
Authors: Choate Robert A. , Ernst Karl D. 
Published: June 2019

At The recent meeting of the Executive Committee of the MENC, which was held in Washington, D.C., in May, the annual report on the Status of the MENC was presented and accepted. The report was then mailed to the Board of Directors. Copies of the report have been made available for presentation and discussion at the Leadership and Planning Conferences of the MENC Divisions being held prior to the 1955 spring meetings of the Divisions. In the opinion of the president of the Conference and the chairman of the Editorial Board of the Music Educators Journal, this report should properly reach all members of the Conference, and it is therefore timely to print it in the Season Preview Issue of the Journal. The report is intended to present an overview of the organization from several standpoints and is organized in four major categories: (1) The Status of MENC Services; (2) the Status of MENC Membership; (3) The Status of MENC Auxiliaries, State Units, Associated Organizations, and other Official Groups; (4) The Status of MENC Publications.
Importance of Treatment Status in Links Between Type 2 Diabetes and Alzheimer’s Disease
Authors: McIntosh Elissa C. , Nation Daniel A. ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: June 2019

OBJECTIVETo investigate relationships among type 2 diabetes treatment, Alzheimer’s disease(AD) biomarkers, and risk for dementia.RESEARCH DESIGN AND METHODSParticipants were from the Alzheimer's Disease Neuroimaging Initiative (N = 1,289) and were dementia-free at baseline and underwent health assessment, cognitive testing, and MRI. A subset (n = 900) obtained a lumbar puncture to determine cerebrospinal fluid (CSF) phosphorylated tau (p-tau), total tau (t-tau), and β-amyloid 1-42 (Aβ1-42). Participants were grouped by fasting blood glucose and medication history: euglycemia (EU), prediabetes (PD), untreated diabetes (UD), and treated diabetes (TD). Relationships were investigated between treatment status and CSF biomarkers and risk for dementia.RESULTSThe UD group displayed greater p-tau, t-tau, and p-tau/Aβ1-42 levels than the EU, PD, and TD groups (P values &lt;0.05) and higher t-tau/Aβ1-42 than the EU and PD groups (P values &lt;0.05). The UD group progressed to dementia at higher rates than the EU group (hazard ratio 1.602 [95% CI 1.057–2.429]; P = 0.026).CONCLUSIONSTreatment status may alter the relationship between type 2 diabetes and both AD biomarker profile and risk for dementia. UD is associated with elevated tau pathology and risk for dementia, whereas TD is not. Although this study is observational and therefore causality cannot be inferred, findings support the potential importance of treatment status in AD risk associated with type 2 diabetes.
Nutrición enteral temprana con inmunonutrientes en pacientes con traumatismo craneoencefálico en la unidad de cuidados intensivos
Authors: Ponce y Ponce de León Gisela , Mayagoitia Witrón José de Jesús , Cornejo Bravo José Manuel , Pérez Morales María Eugenia , Rieke Campoy Ulises , Mayagoitia Ponce Alejandro 
Published: June 2019

El traumatismo craneoencefálico (TCE) es la tercera causa de muerte en México dentro de la categoría de muertes violentas y accidentes, por lo que se considera un grave problema de salud pública. Se ha observado un beneficio de la inmunonutrición temprana en pacientes con TCE. El objetivo de este trabajo fue determinar el impacto de la nutrición enteral temprana con inmunonutrientes (NETI) en la morbimortalidad de pacientes con TCE dentro de la Unidad de Cuidados Intensivos (UCI) del Hospital General de Mexicali. Se trata de un ensayo clínico aleatorizado en el que se incluyeron todos los pacientes con TCE que ingresaron a la UCI del 1 de agosto de 2016 al 30 de junio de 2017. Se conformaron dos grupos: el grupo de estudio sometido a NETI y un grupo control que fue sometido a nutrición enteral temprana licuada (NETL).
Del total de pacientes, 16 fueron hombres (72.7 %) y 6 mujeres (27.3 %), con una media de edad de 34.7 años. Las principales causas del TCE fueron por atropellamiento y accidente de tránsito (54.6 %). El grupo con NETI, en relación con el grupo control, presentó aumento de peso (t de Student de 23.73; p = 0.001), de proteínas totales (t de Student de 13.40; p = 0.001), de leucocitos (t de Student de 2.05; p = 0.002) y linfocitos al egreso de la UCI (t de Student de 7.09; p = 0.001), con disminución en casos de neumonía (t de Student de 13.78; p = 0.001), infección de vías urinarias (t de Student de 8.07; p = 0.001), días de estancia en la UCI (X2 Spearman -.432; p = 0.05), días sometidos a ventilación mecánica (X2 Spearman -.432; p = 0.05) y de nutrición enteral (X2 Spearman -.425; p = 0.05). La mortalidad fue menor en el grupo de NETI sin reportarse una diferencia significativa.
Los pacientes con TCE que recibieron NETI presentaron una disminución en la incidencia de complicaciones infecciosas, así como respecto al tiempo de estancia intrahospitalaria, gracias a lo cual es posible mejorar en menos tiempo la salud del paciente y a la vez reducir costos debidos a la hospitalización.
Merkezi Isıtma Sistemlerinin Uygulanmasında Yaşanan Sorunların Kat Mülkiyeti Hukuku Açısından Sonuçları
Authors: GÜLER Fatih 
Published: June 2019

Kanun koyucu kentleşmenin doğurması muhtemel olumsuzluklarından olan
çevre sorunlarını minimize etmek, kaynakları tasarruflu kullanmak, dışa
bağımlılığı azaltmak ve tüketiciyi korumak gibi amaçlarla belirli büyüklükteki
binalarda merkezi ısıtma sistemini zorunlu hale getirmiştir. Kanun koyucunun beklediği faydaları pratikte
sağlayacak argümanların uygulamasında yaşanan aksaklıklar bağımsız bölüm
kullanıcılarına hukuki sorunlar yumağı olarak dönmektedir. Ferdi ısıtma
sistemlerinde her türlü inisiyatif idareden aldığı izin ve yetkiye dayanarak faaliyet
gösteren uzman bir özel hukuk tüzel kişisinde iken, merkezi ısıtma sistemlerinde
inisiyatifin önemli bir kısmı tüzel kişiliği ve icrai bir yetkisi olmayan yöneticilerde
olması pratikte bir çok sorunu beraberinde getirmektedir. Merkezi ısıtma
sistemini düzenleyen hukuki normlardaki gri alanlar ise bazı durumlarda
hakkaniyete aykırı sonuçlar doğurmaktadır
INTERGOVERNMENTAL RELATIONS DALAM PEMBERIAN KONSESI HUTAN TANAMAN INDUSTRI DI PROVINSI RIAU
Authors: Zainal Zainal 
Published: June 2019

Abstrak Pemberian konsesi hutan tanaman industri di Provinsi Riau tidak hanya melibatkan aktor lokal namun juga melibatkan aktor internasional.Perusahaan swasta seperti PT. RAPP merupakan salah satu perusahaan yang memiliki konsesi hutan tanaman industri terluas di Provinsi Riau saat ini, perusahaan tersebut dan beberapa perusahaan lainnya sudah memiliki konsesi hutan tanaman industri sekitar 2,1 juta hekter di Provinsi Riau.Hasil penelitian ini menunjukan bahwa kebijakan sektor kehutanan kewenangan sepenuhnya menjadi milik Pemerintah Pusat,Pemerintah Daerah Provinsi hanya memiliki kewenangan pada tataran pemberian rekomendasi dan rekomendasi tersebut boleh dugunakan dan boleh juga tidak digunakan oleh Pemerintah Pusat sebagai pertimbangan dalam pemberian konsesi, untuk tingkatan Pemerintah Kabupaten/Kota setelah berlakunya Undang-Undang Nomor 23 Tahun 2014 tentang Pemerintahan Daerah kewenangan sektor kehutanan sudah dicabut dan bahkan dinas kehutanan sudah ditiadakan.Sehingga pada sektor kehutanan kebijakan pemerintah saat dapat disimpulkan kembali menjadi sentralistik. Secara teori intergovernmental relations yang digagas oleh Wrigh (1998) belum mampu menyentuh seluruh aktor yang terlibat dalam pemberian konsesi oleh karena itu diperkuat dengan teori intergovernmental relations yang digagas oleh Jones dan Royles (2012) yang menambahkan international actor sebagai salah satu dimensinya.
Peran Forum Kerukunan Umat Beragama (FKUB) dalam Pembinaan Kerukunan Hidup Beragama Di Luwu Timur
Authors: Kaharuddin Kaharuddin , Darwis Muh. 
Published: June 2019

Penelitian ini bertujuan untuk mengetahui gambaran keberagaman masyarakat dan peran FKUB dalam memelihara harmonisasi trilogi kerukunan beragama masyarakat Luwu Timur. Penelitian ini merupakan jenis penelitian ini menggunakan penelitian kualitatif yaitu penelitian yang mengarahkan penelitiannya pada gejala-gejala yang terjadi pada masyarakat yang berbeda agama. Adapun subjek penelitian ini adalah Forum Kerukunan Umat Beragama (FKUB). Pengurus FKUB Kab. Luwu Timur, Tokoh agama dari masing-masing agama yang ada di Kab. Luwu Timur, Kementerian Agama Kab. Luwu Timur dan Masyarakat Biasa. Hasil penelitian ini menunjukkan bahwa Kabupaten Luwu Timur masyarakatnya sangat majemuk karena terdiri dari berbagai suku, ras, budaya dan agama. Tetapi kemajemukan itu juga masyarakat Luwu Timur sangat toleran. Forum Kerukunan Umat Beragama (FKUB) Luwu Timur sangat strategis dalam membina dan memelihara harmonisasi kerukunan hidup bermasyarakat, berbangsa dan bernegara, terutama dalam memelihara harmonisasi kerukunan hidup beragama, antar umat beragama, dan antar hidup beragama dengan Pemerintah.
HUMANISME KARYA-KARYA SASTRA PRAMOEDYA ANANTA TOER: SEBUAH PERGULATAN DISKURSIF
Authors: Faruk Faruk 
Published: June 2019

Until now Pramoedya Ananta Toer is still recognized as a great Indonesian writer. For this reason, many people doubt that Hanung Bramantyo as popular movie director can perfectly and deeply adapt Pramoedya’s literary works into movies. Some scholars agree that one of the fundamental values in Pramoedya’s works is humanism. However, since Pramoedya visited China and was involved in Lekra, their opinions were split into two categories of humanism: universal humanism on the one hand and the socialist humanism on the other. This research attempted to scrutinize whether Pramoedya is on one of the humanism categories or beyond both categories. Theoretical framework of this research is Laclau and Mouffe’s discourse theory combined with Bhabha’s concept Location of Culture, while the method is the appropriate discourse analysis method. This research found that Pramoedya’s humanism is beyond universal and socialist humanism. In his articulations of humanism as uncovered from his literary works, there are different positions taken by Pramoedya according to different discursive arenas in wich the humanism articulated. In other words, Pramoedya’s postcolonial humanism is located in the liminal area that is always in contestation and negotiation.
Numerical Solution of Abel′s Integral Equations using Hermite Wavelet
Authors: Mundewadi R. A. , Kumbinarasaiah S. 
Published: June 2019

Abstract
A numerical method is developed for solving the Abel′s integral equations is presented. The method is based upon Hermite wavelet approximations. Hermite wavelet method is then utilized to reduce the Abel′s integral equations into the solution of algebraic equations. Illustrative examples are included to demonstrate the validity, efficiency and applicability of the proposed technique. Algorithm provides high accuracy and compared with other existing methods.