bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of fused deposition modeling nozzle types on the structure of 3D printed f-fibers
Authors: Diak Viktorija , Diak Andrii 
Published: November 2024

Abstract

The process of 3D printing is significantly affected by a multitude of adjustable parameters that influence the structure and quality of printed samples. This article aims to investigate the variances in the performance capabilities of nozzles utilized in FDM 3D printers, while also examining the effects of slicer settings and technical methodologies governing filament extrusion. The study explores how the structural design and material composition of these nozzles impact their usual operational efficiency (with PLA) or capacity to print with abrasive materials (TPU + CF). Our evaluation benchmark was established to attain the minimum line width of extrudate (f-fiber), while preserving a consistent physical nozzle diameter. The f-fibers were scrutinized according to various criteria, such as morphology, thermal dependence, extrusion speed, and so on. Our methodological approach entailed formulating hypotheses for each assessment criteria prior to conducting experiments, thereby enabling us to present results as responses to these hypotheses.
The diversity, composition, network characteristics and community assembly of the intestinal microbiome in sea cucumber reflect the differences in habitats and aquaculture practices
Authors: Cui Liang , Wang Bing , Luo Kai , Liu Yang , Xie yumeng , Liu Longzhen , Chen Jianwei , Fan Guanyi , Liu Shanshan , Tian Xiangli 
Published: November 2024

Abstract

Background
The microbiome of aquatic animals can significantly impact the health and farming success of their hosts. However, the possible differentiation of microbiomes in various aquaculture systems has rarely been studied until now. Here, the microbiomes of five different culture systems for sea cucumber Apostichopus japonicus were compared, including the outdoor pond, indoor workshop, net cage, suspension cage, and marine ranching. Samples of intestinal contents from sea cucumber, surrounding water and sediment were collected from the five culture systems. The microbial diversity, composition, co-occurrence network characteristics, and community assembly were analyzed using 16S rRNA high-throughput sequencing technology.
Results
Significant differentiations in the microbial diversity, composition, and function were found in various culture systems. Microbial source-tracking analysis indicated that the intestinal microbiomes of sea cucumber were more similar to the sediment than to the surrounding water. Totally, 23 shared core OTUs were identified in the intestinal microbiome of sea cucumber in the five culture systems, belong to the following orders: Rhodobacterales (15), Rhizobiales (3), Flavobacteriales (2), Verrucomicrobiales (1), Campylobacterales (1), and unclassified (1). Meanwhile, unique core OTUs in various systems tended to aggregate toward oligotrophic, potentially beneficial, or pathogenic bacteria. The microbial co-occurrence network characteristics in the marine ranching and suspension cage systems were consistent with those in high-stress habitats, exhibiting lower diversity, complexity, and modularity, and dominated by positive interactions. Conversely, the opposite trends were observed in the indoor workshop, outdoor pond, and net cage systems. Strong diffusion limitations on the intestinal microbial community of sea cucumber, particularly in the marine ranching system, were elucidated.
Conclusions
The distinct characteristics of the microbiome in various culture systems reflected differences in habitats and aquaculture practices. These findings provide new insights into the impact of aquaculture systems on the microbial community in aquatic animals, and could contribute to healthy aquaculture practices for the sea cucumber industry.
Impact of Helicobacter pylori CagA on E-selectin Levels in Chronic Alcohol Consumers: A Cross-Sectional Study
Authors: Guo Rui , Wang Wanxia , Jia Jing , Wei Chaojun 
Published: November 2024

Abstract

Background
Helicobacter pylori (H. pylori) infection is a major pathogen causing chronic gastritis, peptic ulcers, and gastric cancer. Its major virulence factor CagA and the endothelial adhesion molecule E-selectin play crucial roles in the development of gastrointestinal diseases. This study aimed to investigate the relationship between CagA levels and E-selectin levels in chronic alcohol consumers.
Methods
This cross-sectional study enrolled 112 chronic alcohol consumers. The exposure variable was CagA level, and the outcome variable was E-selectin level. Covariates included age, BMI, alcohol consumption history, daily alcohol intake, oxidative stress markers (MDA, SOD), and inflammatory factors (TNF, IL-10). Multivariable linear regression and piecewise linear regression were used to analyze the relationship between CagA and E-selectin, with subgroup analysis.
Results
CagA levels differed significantly across the high, middle, and low tertiles. CagA levels exhibited a nonlinear relationship with E-selectin levels, with a turning point at 140.8 CagA units, where the effect of CagA on E-selectin changed from positive to negative. Further stratified analysis revealed that in the high alcohol consumption group, CagA levels above 167.8 units had a significantly negative impact on E-selectin.
Conclusion
In chronic alcohol consumers, CagA levels and E-selectin levels have a complex nonlinear relationship, which is modulated by alcohol consumption history. CagA and E-selectin may serve as potential biomarkers for the prevention and management of related gastrointestinal diseases. Further multi-center prospective studies are needed to validate these findings.
The association between fruit and vegetables intake and odds of asthma among children and adolescent
Authors: Rostampour Kimia , sasanfar bahareh , Reshadfar Amirahmad , Emarati Alireza , Nafei Zahra , Behniafard Nasrin , Hashemi-Bajgani Seyed-Mehdi , Salehi-Abargouei Amin 
Published: November 2024

Abstract

Background
Previous epidemiological studies on the correlation between fruit and vegetable consumption and asthma which the majority of them were conducted in developed countries have led to conflicting results. This study aimed to examine the relationship between fruits and vegetable intake and the risk of asthma among a large sample of children and adolescents.
Methods
This cross-sectional study was conducted as part of the Global Asthma Network (GAN) on7667 Iranian children and adolescents. Asthma and its related outcomes were measured using validated questionnaires. A food frequency method was used to assess the dietary intake. The association between fruit and vegetable intake and asthma and its related symptoms was examined using logistic regression.
Results
After adjustment for all possible confounding variables, no significant association was found between fruits and vegetables intake and the odds of medication use for asthma and asthma confirmed by a doctor. However, an inverse significant trend was found between fruits intake and current asthma. In addition, participants with the highest fruits (OR = 0.63; 95%CI: 0.42–0.94, P trend = 0.001) and vegetables (OR = 0.62; 95%CI: 0.48–0.80, P trend < 0.001) intake had a lower chance of wheezing in the past 12 months compared to those with the lowest intake.
Conclusion
Our findings suggest that higher consumption of fruits and vegetables has a protective effect against wheezing in the past 12 months.
MEM-based pangenome indexing for k-mer queries
Authors: Hwang Stephen , Brown Nathaniel K. , Ahmed Omar Y. , Jenike Katharine M. , Kovaka Sam , Schatz Michael C. , Langmead Ben 
Published: November 2024

Abstract

Pangenomes are growing in number and size, thanks to the prevalence of high-quality long-read assemblies. However, current methods for studying sequence composition and conservation within pangenomes have limitations. Methods based on graph pangenomes require a computationally expensive multiple-alignment step, which can leave out some variation. Indexes based on k-mers and de Bruijn graphs are limited to answering questions at a specific substring length k. We present Maximal Exact Match Ordered (MEMO), a pangenome indexing method based on maximal exact matches (MEMs) between sequences. A single MEMO index can handle arbitrary-length queries over pangenomic windows. MEMO enables both queries that test k-mer presence/absence (membership queries) and that count the number of genomes containing k-mers in a window (conservation queries). MEMO's index for a pangenome of 89 human autosomal haplotypes fits in 2.04 GB, 8.8X smaller than a comparable KMC3 index and 11.4X smaller than a PanKmer index. MEMO indexes can be made smaller by sacrificing some counting resolution, with our decile-resolution HPRC index reaching 0.67 GB. MEMO can conduct a conservation query for 31-mers over the human leukocyte antigen locus in 13.89 seconds, 2.5X faster than other approaches. MEMO's small index size, lack of k-mer length dependence, and efficient queries make it a flexible tool for studying and visualizing substring conservation in pangenomes.
Mechanistic Study of Tetracycline Removal and Degradation in Water Using nCo@nZVI Composite Materials within a Fenton System
Authors: WEI Shuxian , ZHANG Lanyue , DU Gang , LI Canhua , HE Chuan , LI Minghui , LI Jiamao , MAO Aiqin , WANG Yanran 
Published: November 2024

Abstract

In response to the increasingly severe antibiotic pollution in water bodies, this study developed a new type of magnetic nano cobalt @ nano zero valent iron that is easy to prepare and inexpensive( nCo@nZVI ) Composite materials. The magnetic sheet-like nZVI was prepared using a rheological phase inversion method, followed by the synthesis of nCo@nZVI through liquid-phase reduction. The material's physical and chemical properties, along with its structure, were meticulously characterized through the utilization of various techniques, including BET, FESEM, XRD, HRTEM, EDS, XPS, and FTIR. Batch experiments were conducted to evaluate the adsorption-degradation mechanism of TC by the material in the Fenton system, and to investigate the effects of factors such as temperature, pH value, and initial TC ion concentration on removal efficiency. The results indicated that under conditions of pH 7 and temperature of 20°C, the nCo@nZVI material could reduce the TC concentration in wastewater from an initial 20mg/L to trace levels within 120 minutes. Adsorption kinetics and isotherm analysis revealed that the adsorption process of TC by nCo@nZVI followed a pseudo-second-order kinetic model and Langmuir isotherm model, indicating predominantly chemical adsorption with an adsorption capacity of 25.33mg/g. Thermodynamic studies have shown that the adsorption of TC by nCo@nZVI occurs spontaneously. Furthermore, the nCo@nZVI composite material is environmentally friendly and cost-effective. It has the advantages of being recyclable and reusable under external magnetic fields, showing great potential in the remediation of antibiotic contaminated sites, and this method has guiding significance for the recovery of cobalt containing wastewater.
COLEC10 interacts with p32 to suppress tumor proliferation in hepatocellular carcinoma via inhibiting autophagy
Authors: Zhang Baozhu , Wang Lu , Xu Yuzhong 
Published: November 2024

Abstract

Background
COLEC10 acts as a tumor suppressor in hepatocellular carcinoma (HCC) by inducing endoplasmic reticulum stress and inhibiting tumor stemness. However, we are curious whether it has other functions and protein interactions in HCC.
Methods
The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO)databases were used to determine COLEC10’s expression level and predictive power. Tumor, plate cloning, soft agar cloning, and nude mouse subcutaneous tumor formation experiments are conducted to detect the effect of COLEC10 on cancer proliferation. Furthermore, we performed KEGG functional enrichment, proteomics, immunoprecipitation, and immunofluorescence to search for proteins that interact with COLEC10.
Results
COLEC10 mRNA was significantly underexpressed in HCC. Overexpression of COLEC10 inhibited tumor growth of HCC cells. Mechanistically, COLEC10 inhibited the autophagy pathway via binding p32. High COLEC10 is positively correlated with the apoptosis pathway and negatively related to DNA replication, myc, and G2M checkpoint-related pathways.
Conclusions
COLEC10 inhibits HCC autophagy by reducing the protein level of p32, which serves as a valuable therapeutic target for HCC.
A preoperative gastrointestinal optimization protocol to improve outcomes after intrathecal baclofen pump surgery
Authors: Mosher Amanda , Hartman Emma , Ruppert-Gomez Marcella , Staffa Steven , Buxton Kristin , Morgan Ann , Muskar Sangeeta , Stone Scellig , Northam Weston 
Published: November 2024

Abstract

Purpose
Pediatric Cerebral Palsy patients carry frequent medical comorbidities and disproportionately consume hospital resources after neurosurgical procedures. We implemented an institutional preoperative gastrointestinal (GI) optimization protocol to improve outcomes and decrease resource utilization.
Methods
All 323 intrathecal baclofen surgeries from 2000–2023 were categorized relative to protocol implementation on July 1st, 2017. Outcomes and resource utilization were compared.
Results
The protocol change resulted in significantly fewer hospital readmissions (p = 0.001) for constipation, eliminating them and GI-related emergency visits. There was a reduction of 27 hospital days for constipation-related readmission (median 1 day per patient, IQR: 1, 2 days). No differences were reported between the experimental groups including demographics or GI comorbidities. Post-operative complications within 30-days were comparable between groups regarding urinary tract infections, surgical-site infections, and spinal fluid leak. There were no differences in postoperative length of stay between groups.
Conclusion
A GI optimization protocol can eliminate a frequent source of hospital readmissions and GI-related emergency department visits after baclofen pump surgery, even accounting for baseline GI comorbidities. Preventing readmissions and emergency visits translates to lower hospital resource utilization and improves quality of care. Future efforts are warranted to improve outcomes and care efficiency for our most complex and resource-intensive patients.
Multiscale cell size analysis for earthquake networks in the complexity-entropy plane of the Colombian seismicity
Authors: León Daniel Andrés , Bucheli Victor Andrés , Valdivia Juan Alejandro 
Published: November 2024

Abstract

Earthquake networks are a representation of seismicity which has brought the use of graph theory conceptual tools to seismology. This research delves into the topologies and complexities of \textit{cells-as-nodes} earthquake networks and tries to elucidate the effect of changing the cell size to create such networks in the resultant topology. In essence, the cell size provides a multiscale microscope that allows to establish the topological properties of the network at different levels. Focusing on the seismicity of Colombia, this research compares earthquake networks with simulated network models, such as Erdős-Renyi, Watts-Strogatz, and Barabási-Albert, and looks into different metrics such as entropy, Complexity, or small-worldness. We find that smaller cell sizes enhance heterogeneity and complexity in earthquake networks; that regardless of cell size, exhibit small-world and scale-free characteristics, with noteworthy variations as we change the cell size.
From Rags to Riches: the Fermentation Potential of Agave Leaf Residues in the Brazilian Semi-arid
Authors: David Ana C. P. , Nogueira Guilherme P. , Santos Jade R. dos , Vargas Beatriz O. , Carazzolle Marcelo F. , Pereira Goncalo , de Mello Fellipe S. B. 
Published: November 2024

Abstract

CAM plants are promising biomasses to assure energy security and biofuel supply in the current changing climate scenario. Their high sugar content and strengthened tolerance to high temperatures and droughts makes them attractive alternatives to classic fuel sources. In Brazil, sisal (Agave sisalana), is cultivated in semiarid regions for fiber production. However, fibers represent only 4% of the plant’s leaves, with the remaining majority being discarded. This work, then, aims to explore this residue’s potential for bioethanol production. For this, low-input fermentations of a fibrous Brazilian agave accession leaves were explored. A maximum ethanol yield of 54.47% (11.64 g.L− 1) was obtained with Kluyveromyces marxianus. Isolating endogenous microbiota activity and fermentation inhibitors (i.e. saponins) revealed major operational challenges. Nevertheless, the results demonstrate that bioethanol production from agave residues is not only attainable but also promising. The unexplored bioethanol potential from this residue in the Brazilian semiarid could yield 489 L.ha− 1.yr− 1, totalizing 639 million liters of fuel, in the last decade.
Green Synthesis of Carbon Quantum Dots from Stale Soy Milk Composited Zinc Oxide (ZnO/CQD) for Photodegradation of Malachite Green
Authors: Widiyandari Hendri , Lestari Putri , Ummah Azza Arba Nurul , Mastura Alief Almasyah Akbar , Parasdila Hanaiyah , Arutanti Osi 
Published: November 2024

Abstract

Visible light-driven photocatalysts are widely investigated to produce high removal efficiency in removing organic pollutants. Carbon quantum dots (CQD) are a plausible candidate for enhancing photocatalytic activity and play an essential role in malachite green (MG) degradation. Biomass waste, stale soy milk, contains lactic acid, which is utilized as a carbon precursor to prepare CQD. ZnO photocatalysts were composited with CQD derived from stale soy milk by green synthesis for the first time. The presence of CQD and their effect on morphology, surface area, decrease in band gap energy, and reduced electron-hole recombination. Indicating that the photocatalytic activity of ZnO/CQD in MG degradation was confirmed after 90 minutes, reaching 84% with a reaction rate constant of 0.01137 k/min-1. Furthermore, the reusability study after four reaction cycles revealed that ZnO/CQD were stable, and scavenger tests were performed to identify the active sites. As a result, we believe that CQD from stale soy milk composited with ZnO is an excellent photocatalyst candidate for removing organic pollutants.
Gry mobilne jako wyznacznik spędzania czasu wolnego: Analiza ilościowa zachowań młodzieży w Polsce z wykorzystaniem metody CATREG
Authors: Dyczewski Błażej 
Published: November 2024

W obecnych czasach młodzież coraz częściej spędza wolny czas, korzystając z urządzeń mobilnych, takich jak tablety i smartfony. Niniejsze badanie analizuje wpływ różnorodnych form aktywności w czasie wolnym na to, z jaką częstotliwością polska młodzież szkół podstawowych angażuje się w gry mobilne. Analiza regresji CATREG na danych z ankiety CAWI wśród 8 350 uczniów z 294 gmin pokazała, że cyfrowe technologie, w tym gry na smartfonach, surfowanie po internecie oraz oglądanie telewizji, mają istotny wpływ na częstotliwość grania w gry mobilne. Aktywności tradycyjne, takie jak czytanie książek i inne hobby również oddziałują na zachowania młodzieży, jednak w mniejszym stopniu. Nie stwierdzono wyraźnego związku między takimi aktywnościami jak gotowanie czy ćwiczenia fizyczne a częstością grania w gry, co podkreśla konieczność prowadzenia dalszych badań w celu identyfikacji dodatkowych czynników mogących mieć wpływ na te tendencje. Takie wnioski mogą okazać się cenne przy tworzeniu interwencji edukacyjnych i socjologicznych mających na celu promowanie zdrowych nawyków cyfrowych oraz rozwijanie kompetencji medialnych.
Elementy stylu życia znanych postaci polskiej sceny medialnej. Studia przypadków.
Authors: Zimnica-Kuzioła Emilia 
Published: November 2024

Celem artykułu jest analiza wybranych elementów stylu życia polskich celebrytów, ludzi, którzy są znani nie tylko dlatego, że - mówiąc językiem K. T. Toeplitza - stali się „mieszkańcami masowej wyobraźni”, ale osiągnęli zawodowy sukces i wysoki status materialny. Inspiracją do napisania artykułu stała się socjologia życia codziennego (Sztompka, Bogunia-Borowska, red. 2008). W części teoretycznej autorka odwołuje się do koncepcji stylu życia, do Goffmanowskiej metafory życia jako teatru, oraz do teorii gustu, habitusu, kapitału kulturowego i społecznego P. Bourdieu.
Bazę empiryczną studium stanowią nagrania kilkudziesięciu odcinków telewizyjnego programu Gwiazdy prywatnie. W celu zilustrowania własnych analiz autorka odwołuje się do wybranych losowo sześciu z nich (wykorzystuje przy tym jedną z jakościowych metod badawczych, jaką jest studium przypadku). Nade wszystko koncentruje swoją uwagę na aspektach wizualnych, m.in. omawia walory estetyczne i funkcjonalne wnętrz, w których toczy się życie codzienne polskich gwiazd sceny medialnej. W mniejszym stopniu na podstawie wypowiedzi celebrytów, rekonstruuje wartości codzienne i uroczyste, którym hołdują, sposób spędzania czasu wolnego, ich pasje, preferencje kulinarne, etc.
Przedstawiciele polskiej „klasy wyżej” najczęściej mieszkają w domach na przedmieściach bądź w luksusowych apartamentach w centrum miasta. Ich mieszkania o dużym metrażu i starannie zaprojektowane ogrody wiele mówią o ich estetycznych gustach. W każdym z mieszkań znajdują się przedmioty związane ze statusem: dobra luksusowe, które dostarczają prestiżu, stanowią czynnik dystynktywny, potwierdzający społeczną wysoką pozycję oraz artefakty nawiązujące do tradycji i przeszłości (pamiątki po przodkach, fotografie dokumentujące ważne zdarzenia i osoby, elementy wyposażenia wnętrz zachowane i przeniesione z domu rodzinnego itp.) W niektórych mieszkaniach zauważyć można obiekty zdradzające zainteresowanie sferą sacrum.
Mother's Perspective and Trust Toward Integrated Services Post (Posyandu) in Indonesia
Authors: Basrowi Ray Wagiu , Farradika Yoli , Sundjaya Tonny 
Published: November 2024

Background
The Integrated Services Post (ISP), also known as Posyandu, is a program designed to enhance maternal and child health by providing integrated basic health services. For years, communities have relied on ISP as a primary source of health information, particularly for maternal and child health needs. This study seeks to assess mothers’ knowledge, perspectives, and family support related to ISP, focusing on maternal understanding, behavior, family support, and trust in ISP services as measured by the Health Collaborative Center Survey.

Methods
A cross-sectional study was conducted using an online survey (Google Form) from February to March 2023. A total of 2,155 mothers were randomly selected as respondents. Data were collected via a self-designed questionnaire adapted from multiple sources, measuring knowledge, behavior, and family support regarding ISP. Descriptive statistical analysis was applied to interpret mothers’ knowledge, behaviors, and levels of family support.

Results
The majority of respondents demonstrated good knowledge of ISP services. Over 98% of mothers correctly identified the appropriate time for weighing children, understood the definition of ISP, and recognized the benefits of weighing children at ISP. More than 70% of mothers correctly answered questions about ISP schedules, recommended child weighing age, and the use of the Health Card (HC). Mothers exhibited positive behavior and high trust toward ISP, with 88.5% strongly believing that ISP can contribute to improving maternal and child health. Family support was generally high, though 4% of respondents reported that their husbands or families opposed immunization, thus limiting their engagement with ISP services.

Conclusion
The majority of mothers in this study possess adequate knowledge, exhibit positive behavior, have high trust in ISP services, and receive substantial family support. Nevertheless, further education and community outreach are needed to improve understanding of severe malnutrition management, the importance of ISP services, and the benefits of immunization.