bluuebunny/crossref_metadata_2025_split huggingface dataset:
“A content analysis of news media coverage of drowning events in Western Australia over two summers, 2014‐2016”
Authors: Leavy Justine E. , Jancey Jonine , Hall Carmen , Nimmo Lauren , Crawford Gemma 
Published: June 2019

AbstractIssue addressedDrowning is a leading cause of death globally. Opportunities to promote drowning prevention in news media may be overlooked for attention‐grabbing headlines, imagery and narrative. This study examines news media coverage of fatal drowning events in Western Australia (WA).MethodsCoronial fatal drowning data in WA were extracted for two summer time periods (2014‐2016) by date, age, gender, location and description. Corresponding print and online news articles were captured using: (i) Media Alert; (ii) Google News; (iii) Factiva. A content and frame analysis protocol was developed. A qualitative approach was taken to analyse the news angle. A subgroup analysis was undertaken for drowning focused articles.ResultsThe final sample (n = 50) news articles matched 17 individual drowning events (T1, n = 9; T2, n = 8). Drowning stories rarely appeared on page 1 (n = 2), but were located in the first 2‐10 pages (n = 20) (66.6%). In the subanalysis, one‐fifth (22%) of the articles employed a news angle relating to community spirit and celebration of life. There were 32 mentions of “who was responsible for the drowning event.” Environmental factors were most cited for “what was responsible” (20.4%). Experts were cited in 66.7% of articles and drowning prevention strategies were mentioned in nine of the 50 articles.ConclusionDrowning was considered newsworthy; however, not the front page news. Reporting infrequently prioritised drowning prevention or discussed prevention strategies.So what?Working closely with news outlets to embed drowning prevention messages in news stories during high‐risk periods such as summer is an imperative.
Characterization of total suspended solid dynamics in a large shallow lake using long‐term daily satellite images
Authors: Hoshikawa Keisuke , Fujihara Yoichi , Siev Sokly , Arai Seiya , Nakamura Takashi , Fujii Hideto , Sok Ty , Yoshimura Chihiro 
Published: June 2019

AbstractLarge, shallow‐water lakes located on floodplains play an important role in creating highly productive ecosystems and are prone to high concentrations of suspended solids due to sediment resuspension. In this study, the aim was to determine the dominant processes governing the total suspended solid (TSS) concentration at the water surface in Tonle Sap Lake, Cambodia, which is a large, shallow‐water lake. Satellite remotely sensed daily reflectance data from 2003 to 2017 were used. Seasonal changes in TSS concentration indicated that bottom sediment resuspension during dry seasons was mostly caused by wind and the TSS concentration was closely correlated with the water depth of the lake. The TSS concentration during flood periods was controlled by both wind and inflow currents from the Tonle Sap River. Additionally, we confirmed that surface/subsurface flow with a low TSS concentration from forests on the floodplain lowered the TSS concentration year round, except during August and September. This fact implied that the floodplain forest area decrease may increase the lake TSS concentration. An analysis of the long‐term changes in TSS indicated that a decrease in the water level during flood periods resulted in the high TSS concentrations observed during the subsequent dry periods. Therefore, climate change and water resource development, which are likely to cause water level reductions in the Mekong River during flood periods, may increase the TSS concentration in Tonle Sap Lake, particularly during the dry season.
A nonstationary runoff frequency analysis for future climate change and its uncertainties
Authors: Li Min , Zhang Ting , Feng Ping 
Published: June 2019

AbstractWith the intensification of climate change, its impact on runoff variations cannot be ignored. The main purpose of this study is to analyse the nonstationarity of runoff frequency adjusted for future climate change in the Luanhe River basin, China, and quantify the different sources of uncertainties in nonstationary runoff frequency analysis. The advantage of our method is the combination of generalized additive models in location, scale, and shape (GAMLSS) and downscaling models. The nonstationary GAMLSS models were established for the nonstationary frequency analysis of runoff (1961–2010) by using the observed precipitation as a covariate, which is closely related to runoff and contributes significantly to its nonstationarity. To consider the nonstationary effects of future climate change on future runoff variations, the downscaled precipitation series in the future (2011–2080) from the general circulation models (GCMs) were substituted into the selected nonstationary model to calculate the statistical parameters and runoff frequency in the future. A variance decomposition method was applied to quantify the impacts of different sources of uncertainty on the nonstationary runoff frequency analysis. The results show that the impacts of uncertainty in the GCMs, scenarios, and statistical parameters of the GAMLSS model increase with increasing runoff magnitude. In addition, GCMs and GAMLSS model parameters have the main impacts on runoff uncertainty, accounting for 14% and 83% of the total uncertainty sources, respectively. Conversely, the interactions and scenarios make limited contributions, accounting for 2% and 1%, respectively. Further analysis shows that the sources of uncertainty in the statistical parameters of the nonstationary model mainly result from the fluctuations in the precipitation sequence. This result indicates the necessity of considering the precipitation sequence as a covariate for runoff frequency analysis in the future.
Multiparameter wide‐field integrated optical imaging system‐based spatially modulated illumination and laser speckles in model of tissue injuries
Authors: Bloygrund Hadas , Franjy‐Tal Yarden , Rosenzweig Tovit , Abookasis David 
Published: June 2019

AbstractIn this report, an integrated optical platform based on spatial illumination together with laser speckle contrast technique was utilized to measure multiple parameters in live tissue including absorption, scattering, saturation, composition, metabolism, and blood flow. Measurements in three models of tissue injury including drug toxicity, artery occlusion, and acute hyperglycemia were used to test the efficacy of this system. With this hybrid apparatus, a series of structured light patterns at low and high spatial frequencies are projected onto the tissue surface and diffuse reflected light is captured by a CCD camera. A six position filter wheel, equipped with four bandpass filters centered at wavelengths of 650, 690, 800 and 880 nm is placed in front of the camera. Then, light patterns are blocked and a laser source at 650 nm illuminates the tissue while the diffusely reflected light is captured by the camera through the two remaining open holes in the wheel. In this manner, near‐infrared (NIR) and laser speckle images are captured and stored together in the computer for off‐line processing to reconstruct the tissue's properties. Spatial patterns are used to differentiate the effects of tissue scattering from those of absorption, allowing accurate quantification of tissue hemodynamics and morphology, while a coherent light source is used to study blood flow changes, a feature which cannot be measured with the NIR structured light. This combined configuration utilizes the strengths of each system in a complementary way, thus collecting a larger range of sample properties. In addition, once the flow and hemodynamics are measured, tissue oxygen metabolism can be calculated, a property which cannot be measured independently. Therefore, this merged platform can be considered a multiparameter wide‐field imaging and spectroscopy modality. Overall, experiments demonstrate the capability of this spatially coregistered imaging setup to provide complementary, useful information of various tissue metrics in a simple and noncontact manner, making it attractive for use in a variety of biomedical applications.
Molecular functions and biological roles of long non‐coding RNAs in human physiology and disease
Authors: Kopp Florian 
Published: June 2019

AbstractThe human genome has been demonstrated to be pervasively transcribed, with a large fraction of the transcriptome representing non‐protein‐coding RNA species. A relatively novel class of non‐coding RNAs, referred to as long non‐coding RNAs (lncRNAs), has attracted increasing attention over recent years. Long non‐coding RNAs comprise a very heterogenous class of transcripts that exert various functions in mammalian cells. Although the number of identified and annotated lncRNAs has been increasing steadily, our understanding of the biological roles for the vast majority of these transcripts remains limited. In this review, a broad concept of the currently known lncRNA modes of action is provided. Examples of mammalian lncRNAs with well‐established biological roles are highlighted and their molecular functions and mechanisms are discussed in detail.
Management of bone disease in cystinosis: Statement from an international conference
Authors: Hohenfellner Katharina , Rauch Frank , Ariceta Gema , Awan Atif , Bacchetta Justine , Bergmann Carsten , Bechtold Susanne , Cassidy Noelle , Deschenes Geroges , Elenberg Ewa , Gahl William A. , Greil Oliver , Harms Erik , Herzig Nadine , Hoppe Bernd , Koeppl Christian , Lewis Malcolm A. , Levtchenko Elena , Nesterova Galina , Santos Fernando , Schlingmann Karl P. , Servais Aude , Soliman Neveen A. , Steidle Guenther , Sweeney Clodagh , Treikauskas Ulrike , Topaloglu Rezan , Tsygin Alexey , Veys Koenraad , v. Vigier Rodo , Zustin Jozef , Haffner Dieter 
Published: June 2019

AbstractCystinosis is an autosomal recessive storage disease due to impaired transport of cystine out of lysosomes. Since the accumulation of intracellular cystine affects all organs and tissues, the management of cystinosis requires a specialized multidisciplinary team consisting of pediatricians, nephrologists, nutritionists, ophthalmologists, endocrinologists, neurologists' geneticists, and orthopedic surgeons. Treatment with cysteamine can delay or prevent most clinical manifestations of cystinosis, except the renal Fanconi syndrome. Virtually all individuals with classical, nephropathic cystinosis suffer from cystinosis metabolic bone disease (CMBD), related to the renal Fanconi syndrome in infancy and progressive chronic kidney disease (CKD) later in life. Manifestations of CMBD include hypophosphatemic rickets in infancy, and renal osteodystrophy associated with CKD resulting in bone deformities, osteomalacia, osteoporosis, fractures, and short stature. Assessment of CMBD involves monitoring growth, leg deformities, blood levels of phosphate, electrolytes, bicarbonate, calcium, and alkaline phosphatase, periodically obtaining bone radiographs, determining levels of critical hormones and vitamins, such as thyroid hormone, parathyroid hormone, 25(OH) vitamin D, and testosterone in males, and surveillance for nonrenal complications of cystinosis such as myopathy. Treatment includes replacement of urinary losses, cystine depletion with oral cysteamine, vitamin D, hormone replacement, physical therapy, and corrective orthopedic surgery. The recommendations in this article came from an expert meeting on CMBD that took place in Salzburg, Austria, in December 2016.
Molecular level comparison of water extractives of maple and oak with negative and positive ion ESI FT‐ICR mass spectrometry
Authors: He Zhongqi , Sleighter Rachel L. , Hatcher Patrick G. , Liu Shasha , Wu Fengchang , Zou Haixuan , Olanya O. Modesto 
Published: June 2019

AbstractSoluble extractives in wood function to protect living trees from destructive agents and also contribute to wood color and fragrance. Some extractive components have biological activities with medical applications. They also play important roles in wood processing and related applications. To increase the knowledge of wood chemistry, maple and oak were extracted by water. Ultraviolet/visible (UV/vis) spectroscopy indicated the presence of a phenolic compound, resorcinol, in maple extractives having higher molecular mass and more aromatic components than oak extractives. Negative and positive electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI FT‐ICR‐MS) identified thousands of formulas in the two samples in the m/z range of 200 to 800. They mainly fall into the lignin‐like, carbohydrate‐like, and tannin‐like compound categories. The top 25 peaks (ie, formulas) with the highest relative magnitude in negative ESI represented nearly 50% of the summed total spectral magnitude of all formulas assigned in the maple and oak extractives. Furthermore, the base peak (ie, most abundant peak) accounted for about 14% of the total abundance in each wood sample. Literature comparisons identified 17 of 20 formulas in the top five peaks of the four spectra as specific bioactive compounds in trees and other plants, implying the potential to explore utilization of maple and oak extractives for functional and medicinal applications. The various profiling of the top 25 peaks from the two samples also suggested the possible application of FT‐ICR‐MS for detecting chemical markers useful in profiling and identification of wood types and sources.
Endocardial biventricular pacing for chronic heart failure patients: Effect on transmural dispersion of repolarization
Authors: Yamin Muhammad , Yuniadi Yoga , Alwi Idrus , Setiati Siti , Munawar Muhammad 
Published: June 2019

AbstractBackground and AimConventional epicardial cardiac resynchronization therapy (CRT) can cause fatal arrhythmia associated with increased transmural dispersion of repolarization (TDR). It is unknown whether endocardial biventricular pacing in various locations will decrease TDR and hence the occurrence of fatal arrhythmia. This study aimed to find out the most effective location of endocardial biventricular pacing resulting in the shortest homogenous TDR.MethodsA before‐and‐after study on adult chronic heart failure (CHF) patients undergoing endocardial biventricular pacing in several defined locations. The changes in TDR from baseline were compared among various pacing locations.ResultsFourteen subjects were included with age ranged 36‐74 years old, of which 10 were males. Location revealed the highest post biventricular pacing TDR (113.4 (SD 13.8) ms) was the outlet septum of right ventricle in combination with lateral wall of left ventricle (RVOTseptum‐LVlateral) while the lowest one (106.1 (SD 11.6) ms) was of the right ventricular apex and posterolateral left ventricle (RVapex‐LVposterolateral). Two CRT locations resulted in the most homogenous TDR, that is the right ventricular apex ‐ left ventricular lateral wall (RVapex‐LVlateral, mean difference −9.43; 95% CI (−19.72;0.87) ms, P = 0.07) and right ventricular apex ‐ left ventricle posterolateral wall (RVapex‐LVposterolateral, mean difference −6.85; 95% CI (−13.93;0.22) ms, P = 0.056).ConclusionEndocardial biventricular pacing on right ventricular apex and left ventricular lateral/posterolateral walls results in the most homogenous TDR.
Incidence and severity of postoperative complications following oral, periodontal, and implant surgeries: A retrospective study
Authors: Askar Houssam , Di Gianfilippo Riccardo , Ravida Andrea , Tattan Mustafa , Majzoub Jad , Wang Hom‐Lay 
Published: June 2019

AbstractBackground: Incidence and severity of postoperative complications are key elements in determining the risk‐benefit relationship of any surgical procedure. The aim of this retrospective study was to assess and categorize the postoperative complications that occur following, and are associated with, oral, periodontal, and implant surgeries.Methods: A total of 3,900 patients who underwent surgical procedures including, but not limited to, sinus floor elevation, guided tissue regeneration, crown lengthening, implant placement, soft tissue graft, open flap debridement or surgical removal of impacted teeth were included. Postoperative complications were recorded and graded based on impedance to routine daily activity and favorable surgical outcomes. Regression models were generated to evaluate correlations between complication types, as well as between patient/surgical characteristics and the incidence of complications.Results: Surgical removal of impacted teeth and lateral sinus floor elevation had the highest incidence and severity of complications. Postoperative dentinal hypersensitivity (5.7%) was the most frequent complication, followed by excessive pain (4.1%), and moderate postoperative bleeding (3.5%). Based on the devised grading system described in this paper, the complications were 11.1% of Grade I, 3.3% of Grade II, 8.3% of Grade III, 0.1% of Grade IV, and no complications recorded under Grades V or VI.Conclusions: Surgical removal of impacted teeth and lateral sinus floor elevation are more prone to more severe complications compared with other procedures. Additionally, complications that do not impede favorable surgical outcomes and/or routine daily activity are the most likely to occur. Smoking and diabetes are generally associated with postoperative complications.
Changes in milk yield and composition of colostrum and regular milk from four buffalo breeds in China during lactation
Authors: Wang Jingxuan , He Yutong , Pang Kun , Zeng Qingkun , Zhang Xiaoying , Ren Fazheng , Guo Huiyuan 
Published: June 2019

AbstractBACKGROUNDChinese local buffalos are mainly used as draft animals because of their low productivity but their crossbreeding with Murrah and Nili‐Ravi breeds can produce offspring with a greatly improved milk yield. However, no studies have reported the characteristics of milk produced during lactation by these crossbred buffalo.RESULTSThis study investigated changes in yield, and the physicochemical composition of milk of Murrah, Nili‐Ravi, Murrah×local, Murrah×Nili‐Ravi×local buffalos with milk yields of 1022.49 ± 90.26 kg, 1193.02 ± 97.65 kg, 805.46 ± 76.57 kg and 1499.35 ± 105.32 kg respectively over a 210‐day period. The protein, fat, ash and total solids contents of milk from the hybrids decreased, but the yield of these nutritional components increased because of the greater improvement in milk yield. As lactation progressed, lactose content increased, but this change was not significant after the 15th day postpartum; the protein content decreased whereas fat content increased significantly during the first three days; ash content changed significantly during the first 24 h postpartum but further changes were not significant. Gel electrophoresis was used to identify the protein profile with no difference found between the four breeds.CONCLUSIONAfter crossbreeding, the milk production of triple‐crossbred buffalo was higher than Murrah, Nili‐Ravi and the local Chinese buffalo, making it a potential resource for the Chinese dairy market. The results of this experiment will provide basic data for making better use of buffalo milk, planning crossbreeding programs, and establishing standards for buffalo milk. © 2019 Society of Chemical Industry
Dietary supplement with nucleotides in the form of uridine monophosphate or uridine stimulate intestinal development and promote nucleotide transport in weaned piglets
Authors: Xie Chun‐yan , Wang Qinhua , Li Guanya , Fan Zhiyong , Wang Hong , Wu Xin 
Published: June 2019

AbstractBACKGROUNDNucleotides are key constituents of milk, where they are utilized in cell replication, although there are limited studies for weaned piglets. This study evaluated the effects of uridine monophosphate (UMP) with uridine (UR) feed supplementation on the intestinal development and nucleotide transport in weaned piglets.RESULTSSupplementation with UMP significantly increased (P < 0.05) plasma glucose, and UR supplementation significantly reduced (0.05 < P < 0.10) the plasma total cholesterol (TC) of piglets when compared with that of the control group, although non‐significant difference (P > 0.05) in growth performance was observed among three groups. Piglets fed supplementary UR exhibited greater (P < 0.05) crypt depth in the duodenum and ileum when compared with those in the supplementary UMP and control groups. Real‐time quantitative polymerase chain reaction (RT‐qPCR) results revealed that UR supplementation increased (P < 0.05) the relative mRNA levels of genes encoding the transmembrane proteins ZO‐1 and occludin in the duodenum mucosa, and ZO‐1 in the jejunum mucosa (P < 0.05). Similarly, UR supplementation increased (P < 0.05) expression of solute carriers SLC28A1 and SLC29A1 in the duodenum mucosa. Conversely, claudin‐1 expression in the duodenum mucosa was inhibited (P < 0.05) by dietary supplementation with UMP or UR.CONCLUSIONCollectively, our data indicated that dietary supplementation with UMP or UR was conducive to stimulating intestinal development and promoting nucleotide transport in weaned piglets. © 2019 Society of Chemical Industry
Preparation of metal‐organic framework UiO‐66‐incorporated polymer monolith for the extraction of trace levels of fungicides in environmental water and soil samples
Authors: Yao Weixuan , Fan Zhefeng , Zhang Suling 
Published: June 2019

AbstractA zirconium terephthalate metal‐organic framework‐incorporated poly(N‐vinylcarbazole‐co‐divinylbenzene) monolith was fabricated in a capillary by a thermal polymerization method. The optimized monolith had a homogeneous structure, good permeability, and stability. The monolith could be used for the effective enrichment of fungicides through π‐π interactions, electrostatic forces, and hydrogen bonds. The potential factors that affect the extraction efficiency, including ionic strength, solution pH, sample volume, and eluent volume, were investigated in detail. The monolith‐based in‐tube solid‐phase microextraction coupled with ultra‐high‐performance liquid chromatography and high‐resolution Orbitrap mass spectrometry was performed for the analysis of five fungicides (pyrimethanil, tebuconazole, hexaconazole, diniconazole, and flutriafol) in environmental samples. Under the optimized conditions, the linear ranges were 0.005–5 ng/mL for pyrimethanil, 0.01–5 ng/mL for flutriafol, and 0.05–5 ng/mL for other fungicides, respectively, with coefficients of determination ≥0.9911. The limits of detection were 1.34–14.8 ng/L. The columns showed good repeatability (relative standard deviations ≤9.3%, n = 5) and desirable column‐to‐column reproducibility (relative standard deviations 5.3–9.4%, n = 5). The proposed method was successfully applied for the simultaneous detection of five fungicides in water and soil samples, with recoveries of 90.4–97.5 and 84.0–95.3%, respectively.