bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mergers and Attributions: An Examination of M&A Terminations in 1996–2022
Authors: Xing Zhe (Adele) , Yi Xiwei 
Published: November 2024

AbstractFirms often make attributions regarding their actions in managing relationships with shareholders and investors. While research utilizing attribution theory has found that firms tend to attribute negative outcomes to external factors and positive outcomes to internal ones, this behaviour can have both positive and negative consequences. Addressing these contrasting results, our paper adopts a multidimensional framework of attribution to study how firms offer explanations for their actions. Leveraging insights from attribution theory and expectancy violation theory, we investigate whether investors respond diversely to firms' heterogeneous attributions for terminating acquisitions. Our findings indicate that an initial positive market reaction to an acquisition announcement is negatively correlated with the market reaction to the acquisition's termination. This negative relationship diminishes when the acquirer attributes the termination to external, uncontrollable and unstable factors. This paper contributes to the acquisition literature by highlighting multiple categories of attributions for firms to strategically manage market reactions.
Changes Over Time in Masseter Muscle Activity, Symptoms of Discomfort, Stress Level and Salivary Flow Rate Following Intra‐Oesophageal Acid Infusion
Authors: Takahashi Kotaro , Maeda‐Iino Aya , Oga Yasuhiko , Osako Yuki , Fukushima Mika , Harada Marina , Nakagawa Shoko , Hino Sayaka , Seong Changkeon , Kanmura Shuji , Ido Akio , Miyawaki Shouichi 
Published: November 2024

ABSTRACTBackgroundIntra‐oesophageal acid stimulation increases masseter muscle activity. However, the infusion speeds used in previous studies are significantly slow, with minimal acid volume (30 mL over 30 min). Additionally, it is unclear how masseter muscle activity, symptoms of discomfort, stress levels and saliva quantity change over time.ObjectivesThe time course of masseter muscle activity, heartburn and discomfort symptoms, salivary cortisol concentration to assess stress, autonomic nervous system (ANS) activity and saliva quantity under the influence of intra‐oesophageal acid infusion were evaluated at a faster injection rate and larger volume than in previous studies.MethodsTen healthy adults underwent polygraphic monitoring, consisting of electromyography of the masseter muscle and electrocardiography during intra‐oesophageal acid infusion (10 mL/min, 10 min). Symptoms of heartburn and discomfort were assessed using the visual analogue scale (VAS), and saliva quantity was measured. Friedman's test was used for multiple comparisons.ResultsMasseter muscle activity, VAS scores for heartburn and discomfort, as well as saliva quantity during the 10‐min acid infusion, increased significantly compared with that before acid infusion (p < 0.001, 0.001, 0.019 and 0.047, respectively) and decreased 10 and 20 min after acid infusion (p = 0.004, 0.004 and 0.007, respectively). No significant changes were observed in the salivary cortisol concentration or ANS activity.ConclusionIntra‐oesophageal acid infusion stimulated symptoms of heartburn and discomfort and increased masseter muscle activity and saliva production, which may not be related to psychological stress.
Analysis of Temporomandibular Disorders, Bruxism and Well‐Being in Patients With Fibromyalgia Syndrome: A Case–Control Study
Authors: Esteve María , Rosales‐Leal Juan I. 
Published: November 2024

ABSTRACTObjectivesTo analyse temporomandibular disorders (TMD), bruxism and well‐being in patients with fibromyalgia and compare these outcomes with a control group.MethodDiagnostic criteria for the assessment of TMD, bruxism and well‐being were used in a clinic context including patients with fibromyalgia (n = 71) and a control group of healthy subjects (n = 151). Participants completed an online questionnaire measuring temporomandibular pain, headache attributed to TMD, jaw locking, joint sounds, headache to bruxism, potential sleep bruxism, potential awake bruxism, jaw functional limitation scale 8 (JFLS‐8), generalised anxiety disorder scale 7, oral health impact profile scale 14, World Health Organization well‐being index (WHO‐5) and Pittsburgh sleep quality index (PSQI).ResultsTMD and bruxism were significantly associated with the type of population (χ2 = 8.77–57.62; p < 0.05; ES = 0.20–0.51). Fibromyalgia patients showed higher prevalence (% values) than control group in temporomandibular pain, headache attributed to TMD, jaw locking, headache attributed to potential bruxism, sleep bruxism and awake bruxism. However, there was a greater prevalence of joint sounds in the control group compared to the fibromyalgia group. Also, fibromyalgia patients scored significantly higher (p < 0.001) on JFLS‐8, GAD‐7, OHIP‐14 and PSQI with a large effect size (ES = 0.51–0.73), while WHO‐5 scores were significantly lower (ES = 0.58).ConclusionPatients with fibromyalgia had greater prevalence than the control group in TMJ pain, headache attributed to TMD, jaw locking, headache attributed to bruxism, sleep bruxism and awake bruxism. Another main finding was that patients with fibromyalgia had greater jaw functional limitation, generalised anxiety and impact of oral health on an individual's life. In addition, fibromyalgia patients showed lower sleep quality and well‐being index.
Dark ventral colouration indicates head size in a semi‐colonial gecko
Authors: Comas M. 
Published: November 2024

AbstractSeveral animals present ornamental colouration which acts as signals in sexual or other social contexts by indicating some trait of the bearer. This colouration is often present only in one sex and may be produced by a varied combination of structural elements and several pigments. Given that colours may be produced in different ways, the traits the colouration is indicating, and the costs or trade?offs associated, may differ according to the colour and the species studied. Here, I study a dark ventral colouration present in males of the gecko Quedenfeldtia trachyblepharus, a high‐altitude, semi‐colonial lizard endemic to the High Atlas in North Africa. I tested for the correlation between the extension of the dark colouration and several morphological traits (body size, head size and limb length) in the gecko, as well as parasitism by mites and age. No relationship was found between dark colouration and parasitism, age and limb length, but the extension of the dark colouration was positively correlated with head size controlled for body size. Given that head size is usually a good indicator of fighting capacity, and this gecko shows a strong social structure, the findings suggest that the dark colouration is used in agonistic encounters among males, allowing for evaluation of the fighting capacity of the rivals.
PNPLA3 I148M Interacts With Environmental Triggers to Cause Human Disease
Authors: Speliotes Elizabeth K. , Schneider Carolin Victoria 
Published: November 2024

ABSTRACTBackgroundMetabolic dysfunction‐associated steatotic liver disease (MASLD) affects up to 30% of Western populations. While obesity is a recognized risk factor, MASLD does not develop in all obese individuals, highlighting the need to understand genetic and environmental interactions. The PNPLA3 I148M variant has been identified as a key genetic risk factor, significantly increasing the likelihood of MASLD development and progression.MethodsWe reviewed current literature on the role of PNPLA3 I148M in MASLD, focusing on gene‐environment interactions involving diet, physical activity, obesity, and insulin resistance. We included studies analysing ethnic differences in PNPLA3 I148M prevalence and its association with MASLD. Additionally, we reviewed data on how PNPLA3 I148M influences the response to therapies, including lipid‐lowering medications and GLP‐1 agonists.ResultsThe PNPLA3 I148M variant markedly heightens MASLD risk, particularly in Hispanic populations, where a higher prevalence of MASLD is observed. Lifestyle factors such as high sugar intake, alcohol consumption, and physical inactivity exacerbate MASLD risk among I148M carriers. Evidence shows that insulin resistance amplifies MASLD risk associated with the I148M variant, especially in non‐diabetic individuals. Moreover, the PNPLA3 I148M variant interacts with other genetic loci, further modifying MASLD risk and disease course. The variant also influences treatment response, with variability observed in effectiveness of lipid‐lowering therapies and GLP‐1 agonists among carriers.ConclusionThe interplay between PNPLA3 I148M and environmental factors underscores the need for personalized MASLD prevention and treatment strategies. Targeting both genetic and lifestyle contributors may enhance MASLD management, offering a tailored approach to reducing disease burden.
Balancing Knowledge and Health: A Comparative Analysis of Students and Healthcare Workers Nutrition Related Health Behaviors, a Cross‐Sectional Study
Authors: Zaitoon Hussein , Kaly Lisa , Khalil Hadel , Zion Nataly 
Published: November 2024

ABSTRACTThe study aimed to investigate nutrition‐related health behaviors among nursing and medical students compared to healthcare workers (HCWs), including nurses and physicians. A cross‐sectional survey was conducted between May and November 2022, using the I‐MEDAS and lifestyle‐related behavior questionnaires. The participants included nursing and medical students, nurses, and physicians, with a total of 384 participants: 16.9% physicians, 23.17% nurses, and 59.9% students, 93% of whom were nursing students. The average I‐MEDAS score (out of 17) was 7 for physicians, 8 for nurses, and 8 for students, with no significant differences in lifestyle behavior scores between the groups (p = 0.11), although nurses tended to score lower. Nurses also had a significantly higher BMI compared to physicians and students (p < 0.001). Physicians and nurses reported lower engagement in leisure activities and household chores, fewer sleep hours, and poorer sleep quality. The findings highlight a decline in healthy lifestyle behaviors and poor adherence to the Mediterranean diet among HCWs and students, particularly nurses, emphasizing the need for interventions to promote healthier habits in these groups.
New Minimally Invasive Method for Treating Posterior Pelvic Ring Fractures: Biomechanical Validation and Clinical Application of Sacroiliac Joint Locking Plate
Authors: Jin Liang , Hao Xiaorui , Zhang Zhenzhu , Zhang Qiaoli , Zhang Shuxin , Zhou Fei , Yang Shuirong , Zheng Weijie , Xiong Xiaohui , Gong Wanchen , Wang Yukun , Chen Xiaojie , Huang Jiexin 
Published: November 2024

ABSTRACTObjectiveConsidering the high incidence and complexity of unstable posterior pelvic ring fractures, and the need for less invasive and more effective treatment options, this study aims to introduce a novel minimally invasive, safe, and simple internal fixation method for the treatment of unstable posterior pelvic ring fractures using the sacroiliac joint locking plate (SJP) system, and to provide biomechanical validation and clinical evaluation of this method.MethodsBiomechanical research was conducted using standard pelvic bone models from Synbone, Switzerland, to create Denis II zone unstable posterior pelvic ring fracture models, and to assess the stability of the SJP under different loads compared with traditional fixation methods. A retrospective clinical study analyzed the clinical efficacy of SJP treatment in 62 patients (mean age of 51.7 ± 11.9 years and male‐to‐female ratio of 42/20) treated at our hospital from October 2016 to January 2023.ResultsBiomechanical tests showed that at a maximum load of 300 N, the displacement values for the SJP (3.361 ± 0.246 mm) and two iliosacral (IS) screws (3.325 ± 0.335 mm) were significantly lower than those for a single IS screw (4.281 ± 0.399 mm) and tension band plate (TBP) (4.678 ± 0.534 mm). In the stiffness test of the compression‐separation experiment, the average stiffness of the SJP (92.09 ± 1.17 N/mm) was higher than that of a single IS screw (80.06 ± 2.57 N/mm) and TBP (71.67 ± 1.12 N/mm) (p < 0.05 for both), but lower than that of two IS screws (104.94 ± 1.16 N/mm) (p < 0.05). Clinically, postoperative pain scores decreased to 1.9 ± 0.9 after SJP surgery, which was a significant reduction compared with the preoperative score of 9.1 ± 1.1. Functional prognosis scores improved from 36.1 ± 11.5 preoperatively to 88.4 ± 14.2, showing a marked improvement. The postoperative Majeed scores for the patients were 87.4 ± 8.1, and the incidence of complications was low, with only one case reported so far.ConclusionThe SJP demonstrates robust stability in biomechanical experiments, making it highly advantageous for clinical applications and widespread adoption. It offers several benefits, including straightforward surgical operation, minimal risk of vascular and neural injury, low surgical requirements, and eliminates the need for fluoroscopy. These advantages contribute to its remarkable clinical efficacy and potential for extensive utilization.
A pilot study of novel ultrahigh‐frequency dorsal root ganglia stimulation for chronic lower limb pain: Focusing on safety and feasibility
Authors: Lee Shang‐Yi , Hsiung Nai‐Huan , Chapman Kenneth B. , Cheng Yu‐Kai , Huang Chieh‐Liang , Chen Kuen‐Bao , Chang Chi‐Heng , Wen Yeong‐Ray 
Published: November 2024

AbstractObjectivesThis single‐arm, open‐label, single‐center observational pilot study assessed the safety and efficacy of ultrahigh‐frequency dorsal root ganglia (UHF‐DRG) stimulation in patients with chronic leg pain with or without low back pain. Such high‐frequency electrostimulation had not been conducted in the human central nervous system previously.Materials and MethodsThe primary objective was to evaluate the safety of UHF‐DRG stimulation (2 Hz pulses with 50 msec pulse‐width and 500 kHz intrapulse sine waves, 5‐min duration per stimulation) by identifying incident adverse events (AE) and severe adverse events (SAE) during the trial. The secondary objectives included assessment of pain reduction using a numerical rating score (NRS), presence of paraesthesia, and changes in four pain medications (weak opioids, anticonvulsants, antidepressants, and non‐steroid‐anti‐inflammatory drugs). One DRG lead was implanted for one day then removed, and the patients received maximal three times of UHF stimulation in total.ResultsThe study focused on ten cases. Two of them did not complete the study due to difficulty of lead implantation. There was no SAE in this trial. Among the ten cases, AEs occurred in eight, three experienced injection‐related local pain and one of them had a post‐dural‐puncture headache, others had symptoms un‐related to implantation procedure or UHF stimulation. The average NRS was reduced from 6.4 ± 1.1 at baseline to 2.9 ± 1.1 on the second‐day post‐implantation, and it was striking that the NRS was maintained at 3.6 ± 2.8 until 2 days after lead removal. The results showed a trend of lower frequency in medication use for all types of analgesics.ConclusionsIn this first‐in‐human pilot study, we discovered that intermittent pulsed UHF‐DRG stimulations ameliorated chronic lower limb pain for an extended period in humans. Our finding opens up a new neuromodulatory concept and may initiate a novel paradigm for treating intractable pain.
A Key R2R3‐MYB Transcription Factor Activates Anthocyanin Biosynthesis and Leads to Leaf Reddening in Poplar Mutants
Authors: Li Weinan , Li Qianqian , Che Jiahang , Ren Jie , Wang Aike , Chen Jinhuan 
Published: November 2024

ABSTRACTColorful woody plants are highly valued for their ornamental qualities, and are commonly used in garden landscape design. We previously cultivated several ornamental poplar varieties from bud mutants of Populus sp. Linn. ‘2025’ (ZL2025), each with different leaf colors. Based on transcriptome data from these varieties with varying anthocyanin pigmentation, we identified and named an R2R3‐MYB gene, PdMYB113. The mRNA of PdMYB113 accumulated in the leaves of the red‐leaf mutants ‘QHY’ and ‘LHY’, but barely expressed in the leaves of ‘ZL2025’. The anthocyanin biosynthesis genes were upregulated, resulting in high levels of red anthocyanins (particularly Peonidin‐3‐O‐rutinoside, Cyanidin‐3‐O‐rutinoside, and Cyanidin‐3‐O‐glucoside) in both OE‐PdMYB113 tobacco and poplar plants. This upregulation caused a color change in the tissues from green to red or dark purple. Yeast one‐hybrid and luciferase assays demonstrated that PdMYB113 activates the expression of anthocyanin biosynthesis genes, including the early anthocyanin biosynthetic gene PdCHS and the late anthocynin biosynthetic gene PdANS. Consequently, PdMYB113 is identified as a key regulator of red coloration in poplar. Additionally, PdMYB113 does not dwarf transgenic plants under normal lighting conditions. This study elucidates the regulatory mechanisms of color change in ZL2025 and highlights a crucial gene for breeding new varieties of woody plants.
Cytosolic fructose‐1,6‐bisphosphatase isoform mediates metabolic adjustments in bean fruit pericarp to support seed growth
Authors: Bernal Lilia , Coello Patricia , Padilla‐Chacón Daniel , Martínez‐Barajas Eleazar 
Published: November 2024

AbstractSeed development requires substantial metabolic resources and is influenced by adverse environmental conditions. However, the ability of plants to produce viable seeds under restrictive conditions suggests the existence of mechanisms that make this process less sensitive to environmental stress. Uncovering their regulation could lead to the development of genotypes better adapted to stressful conditions. Plant response to stress is complex, and the contribution of organs such as the fruit pericarp to stress tolerance mechanism may have been underestimated. The bean fruit pericarp, a photosynthetic structure that contributes to seed development, can synthesize starch from surplus sucrose, which is later degraded during the rapid seed growth phase. This metabolic flexibility may be crucial for supporting seed growth when the photosynthate supply is reduced. To explore this possibility, we disrupted phloem continuity at the pedicel level in fruits about to enter the seed reserve accumulation stage. We used the capacity of the pericarp to incorporate 14CO2 to investigate changes in its metabolism. Our findings reveal that, in response to reduced photosynthate availability, the fruit pericarp did not increase 14CO2 fixation. However, the amount of 14C used for starch synthesis decreased, while the proportion used for soluble sugars synthesis increased. This shift resulted in an increase in 14C‐products transported to seeds was accompanied by a significant increase in the activity of cytosolic fructose 1,6‐bisphosphatase. Our results indicate that photosynthate restriction accelerates the degradation of pericarp storage proteins, and the increase in cFBPase activity could be crucial in converting the carbon produced in carbohydrates.
Interlocal learning mechanisms and policy diffusion: The case of new energy vehicles finance in Chinese cities
Authors: Liu Weixing , Ma Liang , Wang Xuan , Yi Hongtao 
Published: November 2024

AbstractPolicy diffusion based on learning mechanisms has fascinated political science and public administration scholars for a long time. A robust and growing body of studies have identified the existence and importance of learning mechanisms in policy diffusion. However, there are still some gaps that need to be further improved. First, scholars identify the learning mechanism mainly based on indirect evidence, such as geographical proximity and successful innovation policies adopted by other jurisdictions, which lacking direct and systematic evidence. Second, little is known about how the hierarchical power structure affects the leap from learning behavior to policy adoption. This study provides direct evidence for the promoting effect of intergovernmental learning on policy diffusion by analyzing case of Chinese local financial subsidy policies for new energy vehicles. The empirical results reveal that policy learning in the form of site visits among local governments significantly promotes the policy diffusion, but superior government policy strategy attenuates the influence of interlocal learning on policy diffusion. Also, the initiators and themes of policy learning affect the learning–diffusion linkage, portraying the conditional effects and nuanced dynamics of interlocal policy learning in eliciting policy diffusion.
Expressed emotion and help‐seeking behaviours among elderly adults with depression symptoms in northeast Malaysia: qualitative findings from a mixed methods investigation
Authors: Sanggar Arunah , Razak Asrenee Ab , Phoa Picholas Kian Ann 
Published: November 2024

ABSTRACTBackgroundStressful life events greatly increase the risk of depression, which affects about 22% of older persons in northeast Malaysia. But how emotional distress manifests itself in reaction to these stressful events differs from person to person. Therefore, this study aims to delve into the nuances of emotional expression among older adults with depression symptoms in northeast Malaysia, alongside their help‐seeking behaviours and utilisation of professional support.MethodsUsing a qualitative interpretative phenomenological approach, we conducted in‐depth face‐to‐face interviews with participants, guided by Kleinman's explanatory model of illness. Nineteen older adults who screened positive for depression were included in the research.ResultsNone of the participants explicitly acknowledged experiencing depression. However, they articulated their distress through three primary themes: ‘Life is miserable,’ ‘Depression is a sign of weakness,’ and ‘Belief in pre‐determination.’ Remarkably, despite screening positive for depression, participants demonstrated a lack of awareness regarding available professional mental health services. Moreover, they expressed a reluctance to seek such services, citing reasons related to stigma and misconceptions. The predominant themes that emerged concerning help‐seeking behaviours were ‘Self‐efficacy,’ ‘Social support,’ and ‘Formal assistance from non‐mental healthcare professionals.’ConclusionThe expression of emotion among older adults is restricted by socio‐cultural influences. Thus, there is a need to improve mental health literacy among older adults in Malaysia, and their preferred source of support such as religious leaders and non‐mental healthcare physicians.