bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interventions to improve the continuity of medication management upon discharge of patients from hospital to residential aged care facilities
Authors: Fredrickson Brodie‐Anne , Burkett Ellen 
Published: April 2019

AbstractAimThe aim of this study was to undertake a systematic review of the literature and evaluate interventions used to improve continuity of medication management upon transition of care from an acute hospital setting to a residential aged care facility (RACF).Data sourcesEmbase, PubMed, The Cochrane Database of Systematic Reviews, Google Scholar, Informit Health Collection, grey literature and reference mining of included studies (from inception to March 2018).Study selectionInterventions aimed at improving the continuity of medication management upon discharge of patients from hospital to an RACF or similar facility were included. Interventions were defined as a communication tool or a service initiated by any healthcare professional. Studies were excluded if they were not available in English, had certain study designs (i.e. qualitative, observational and systematic review) and if no abstract and full‐text article could be obtained.ResultsSeven studies met the inclusion criteria. All interventions involved a multidisciplinary approach to discharge facilitation including the provision of discharge medication information. Six studies included pharmacist‐led medication reconciliation. Two studies used an RACF‐specific medication chart. Although positive findings were shown for most interventions, critical analysis of the studies included identified many limitations.ConclusionInterventions involving a multidisciplinary team, pharmacist‐led medication reconciliation and the provision of accurate discharge information have been identified as improving continuity of medication management during transitions of care from hospital to RACF. Importantly, this systematic review has identified an ongoing need for development of a comprehensive intervention that addresses all barriers to optimal continuity of medications encountered during this high‐risk transition.
Selenium‐enriched Coriolus versicolor mushroom biomass: potential novel food supplement with improved selenium bioavailability
Authors: Miletić Dunja , Turło Jadwiga , Podsadni Piotr , Pantić Milena , Nedović Viktor , Lević Steva , Nikšić Miomir 
Published: April 2019

AbstractBACKGROUNDThe ability of Coriolus versicolor medicinal mushroom to accumulate and transform selenium from selenourea and sodium selenite into an organic form – l‐selenomethionine – during growth in liquid medium is examined in this paper. Additionally, the impact of supplementation on biological activity of the selenated mushroom methanol extracts, as well as their chemical composition, is studied.RESULTSSelenium accumulation was more efficient with sodium selenite application, but biomass yield was significantly lower (1.89 g DW L−1) compared to samples enriched with selenourea (4.48 g DW L−1). Mushroom sample obtained after growing in liquid medium with selenourea had significantly higher l‐selenomethionine content compared to the sample grown in medium with sodium selenite. Selenium‐enriched methanol extracts of C. versicolor mushroom showed improved antimicrobial and antioxidant activities compared to non‐enriched extract.CONCLUSIONOur results suggest that C. versicolor mushroom cultivated in liquid culture enriched with selenourea can be used for the production of novel food supplements with improved selenium bioavailability. More than 30% of total accumulated selenium from selenourea is transformed into l‐selenomethionine. Differences in biological activity of methanol extracts can be explained not only by different selenium content but also by the differences in chemical composition of extracts. © 2019 Society of Chemical Industry
Does drug‐induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
Authors: Pang Kenny P. , Baptista Peter M. , Olszewska Ewa , Braverman Itzhak , Carrasco‐Llatas Marina , Kishore Srivinas , Chandra Sudipta , Yang Hyung Chae , Wang Cybil Mei Zhi , Chan Yiong Huak , Pang Kathleen A. , Pang Edward B. , Rotenberg Brian 
Published: April 2019

Objectives/HypothesisOur objective was to determine whether drug‐induced sleep apnea (DISE) affects the successfulness of the surgical outcome.Study DesignProspective, seven‐country, nonrandomized trial.MethodsThere were 326 consecutive obstructive sleep apnea (OSA) patients who had nose, palate, and/or tongue surgery included in the study. DISE was performed in only one group.ResultsThere were 170 patients in the DISE group and 156 patients in no‐DISE group. The mean preoperative body mass index (BMI) for the DISE group was 27.6 ± 4.6, whereas in the no‐DISE group it was 28.1 ± 3.9 (P = .23). The mean preoperative systolic blood pressure (SBP) for the DISE group was 130.4 ± 16.7, whereas in the no‐DISE group it was 142.9 ± 15.5 (P < .001). The mean preoperative diastolic blood pressure (DBP) for the DISE group was 81.4 ± 9.7, whereas in the no‐DISE group it was 89.1 ± 9.7 (P < .001). The mean preoperative apnea‐hypopnea index (AHI) for the DISE group was 32.6 ± 18.8, whereas in the no‐DISE group it was 33.7 ± 19.6 (P = .61). The mean postoperative AHI for the DISE group was 15.9 ± 12.6, whereas in the no‐DISE group it was 13.2 ± 8.8 (P = .023). The age‐, gender‐, BMI‐adjusted percentage change in AHI for the DISE group was −48.4 ± 31.9, whereas in the no‐DISE group it was −59.8 ± 18.6 (P < .001). The age‐, gender‐, and BMI‐adjusted success rate for the DISE group was 66.5%, whereas in the no‐DISE group it was 80.8% (P = .004). The age‐, gender‐, and BMI‐adjusted change in SBP for the DISE group was −6.1 ± 8.6, whereas in the no‐DISE group it was −13.3 ± 11.1 (P < .001). The age‐, gender‐, and BMI‐adjusted change in DBP in the DISE group was −5.2 ± 12.1, whereas in the no‐DISE group it was −12.4 ± 11.7 (P < .001). The mean age‐ and gender‐adjusted change in BMI for the DISE group was −4.6 ± 12.9, whereas in the no‐DISE group it was −6.3 ± 18.5 (P = .34). The Cohen effect of BMI on the overall AHI, lowest oxygen saturation, and blood pressure changes was 0.08.ConclusionsDISE may not significantly affect surgical success in OSA.Level of Evidence2c Laryngoscope, 130:551–555, 2020
Syringomyelia‐Associated Dystonia: Case Series, Literature Review, and Novel Insights
Authors: Mulroy Eoin , Balint Bettina , Latorre Anna , Schreglmann Sebastian , Menozzi Elisa , Bhatia Kailash P. 
Published: April 2019

ABSTRACTBackgroundSyringomyelia has previously been suggested as a potential trigger of secondary dystonia. However, a definite causal relationship between the conditions remains to be established. We describe 4 cases of syrinx‐associated dystonia, review past literature on the subject, and propose novel pathophysiological insights into this association.MethodsWe reviewed demographic, clinical, and neuroradiological features in 4 cases of syrinx‐associated dystonia. A retrospective review of previously published literature on the subject was also conducted.ResultsPatients with syrinx‐associated dystonia were younger than those with primary dystonia. None had sensory gestes. Syringomyelia frequently involved the cervical cord. Arnold‐Chiari type 1 malformation was a common finding. Some patients responded to botulinum toxin and syrinx decompression.ConclusionFurther work is needed to clearly establish the correlation between syringomyelia and dystonia. However, plausibly, syrinx‐related disruption of the dystonia network (through alterations in sensory inputs, loss of inhibition and cerebellar abnormalities) could explain the association.
Improvement of bioactive metabolite production in microbial cultures—A systems approach by OSMAC and deconvolution‐based 1HNMR quantification
Authors: Selegato Denise Medeiros , Freire Rafael Teixeira , Pilon Alan César , Biasetto Carolina Rabal , de Oliveira Haroldo Cesar , de Abreu Lucas Magalhães , Araujo Angela Regina , da Silva Bolzani Vanderlan , Castro‐Gamboa Ian 
Published: April 2019

AbstractTraditionally, the screening of metabolites in microbial matrices is performed by monocultures. Nonetheless, the absence of biotic and abiotic interactions generally observed in nature still limit the chemical diversity and leads to “poorer” chemical profiles. Nowadays, several methods have been developed to determine the conditions under which cryptic genes are activated, in an attempt to induce these silenced biosynthetic pathways. Among those, the one strain, many compounds (OSMAC) strategy has been applied to enhance metabolic production by a systematic variation of growth parameters. The complexity of the chemical profiles from OSMAC experiments has required increasingly robust and accurate techniques. In this sense, deconvolution‐based 1HNMR quantification have emerged as a promising methodology to decrease complexity and provide a comprehensive perspective for metabolomics studies. Our present work shows an integrated strategy for the increased production and rapid quantification of compounds from microbial sources. Specifically, an OSMAC design of experiments (DoE) was used to optimize the microbial production of bioactive fusaric acid, cytochalasin D and 3‐nitropropionic acid, and Global Spectral Deconvolution (GSD)‐based 1HNMR quantification was carried out for their measurement. The results showed that OSMAC increased the production of the metabolites by up to 33% and that GSD was able to extract accurate NMR integrals even in heavily coalescence spectral regions. Moreover, GSD‐1HNMR quantification was reproducible for all species and exhibited validated results that were more selective and accurate than comparative methods. Overall, this strategy up‐regulated important metabolites using a reduced number of experiments and provided fast analyte monitor directly in raw extracts.
Exploring thoughts about pain and pain management: Interviews with South Asian community members in the UK
Authors: Burton Amy E. , Hissey Laura , Milgate Sarah 
Published: April 2019

AbstractObjectiveThis research sought to explore the pain management beliefs of members of the South Asian community living in the UK. In particular, their understanding of the key components of cognitive behavioural therapy (CBT) informed pain management programmes (PMPs) was explored.MethodsSnowball sampling was used to recruit 10 participants from a South Asian background for interview. Interviews were guided by a semi‐structured interview schedule and explored pain history, specific pain experiences, community member expressions of, and reactions to, pain, treatment expectations and perceptions of self‐management. Interviews were transcribed verbatim and subjected to descriptive thematic analysis.ResultsFour themes were developed: impacts of chronic pain, within‐group variations in responses to chronic pain, personal responsibility vs. paternalistic care, and the acceptability of pain management concepts (relaxation and meditation, exercise and physical activity, and thoughts and beliefs: the dangers of pain healers).ConclusionsThis work highlights how discourses around the impacts of chronic pain; beliefs about, and preferences for, approaches to care; and the acceptability of pain management concepts fit with existing PMP content. Recommendations are made regarding opportunities for social prescribing; consideration of the incorporation of acceptable forms of physical activity, including yoga and walking, within PMPs; and the potential benefit of highlighting role models and creating social opportunities for these activities. Some beliefs and practices in this area are under‐researched, and further work that explores gender and generational differences in pain perceptions, and the potential dangers of the use of pain healers is needed.
Achieving and Maintaining Perceptual Intent with HDR Imaging
Authors: Kunkel Timo , Wanat Robert 
Published: April 2019

AbstractThough displays have undergone dramatic shifts in the last 30 years, many of the imaging pipeline elements needed to create a compelling visual experience have only started to catch up as HDR becomes more prominent. Here, a look at how those new elements are being incorporated and what the changes mean for the industry.
Understanding RGB Color Spaces for Monitors, Projectors, and Televisions
Authors: Sharma Abhay 
Published: April 2019

AbstractColor imaging has many exciting new advances related to gamut, luminance, color spaces, quantum dots, and high dynamic range (HDR). In this short primer—the first of a two‐part series—we examine three color‐space specifications: Recommendation (Rec.) 709, Digital Cinema Initiatives (DCI)‐P3, and Rec. 2020.
Qualitative analysis of patient responses to the ABCD FreeStyle Libre audit questionnaire
Authors: Overend Louise , Simpson Emma , Grimwood Tom 
Published: April 2019

AbstractThe Abbott FreeStyle Libre flash glucose monitoring system is a novel sensor‐based, factory‐calibrated device that allows individuals with diabetes to monitor their interstitial glucose levels, capture up to 8 hours of interstitial glucose data, and predict future changes in interstitial glucose by scanning a temporary implantable glucose sensor with a reader device or compatible mobile phone.The study aim was to determine whether use of a flash glucose monitoring system had an impact on quality of life and to explore why this was the case.Raw data were collected as part of a brief semi‐structured interview supported by the ABCD FreeStyle Libre Follow‐Up Visit Data Collection form. Data were collected pragmatically at outpatient clinic follow‐up visits, and the first 40 patients to complete six months of continuous use were included in the study.Feedback on use of the device was overwhelmingly (although not unanimously) positive. A number of basic themes were identified independently by the investigators, which were then grouped into four organising themes: Contrast with capillary blood glucose monitoring; Impact on hypoglycaemia experience; Glycaemic control and complications; and Improved wellbeing and quality of life. These themes are analysed and illustrated in the article. Copyright © 2019 John Wiley & Sons.
Determining the excited‐state substituent constants of ortho‐substituents from 2,4’‐disubstituted stilbenes
Authors: Cao Chao‐Tun , Yuan Hua , Zhu Qian , Cao Chenzhong 
Published: April 2019

AbstractThere are mainly three kinds of substituent electronic effects derived from aromatic rings: ground‐state, radical‐state, and excited‐state effect. However, excited‐state substituent constants of ortho‐substituents have not been reported up to now. In this paper, a method for extracting the excited‐state substituent constant
of ortho‐substituents was provided. Forty‐nine 2,4’‐disubstituted stilbenes were synthesized, and the ultraviolet absorption spectra of the synthesized stilbenes were determined. The
values of ortho‐substituents involving MeO, Me, F, Cl, Br, CF3, and CN were quantified by curve fitting method based on the measured ultraviolet absorption spectra. The rationality of the
values were further experimentally confirmed by measuring the ultraviolet absorption spectra of other 10 samples of synthesized 2,3’‐disubstituted stilbenes and by applying these
values in regression analysis of the ultraviolet absorption spectra for a complicated data set of 284 organic compounds.
Engineering Ultrathin MoS2 Nanosheets Anchored on N‐Doped Carbon Microspheres with Pseudocapacitive Properties for High‐Performance Lithium‐Ion Capacitors
Authors: Jiang Jiangmin , Zhang Yadi , An Yufeng , Wu Langyuan , Zhu Qi , Dou Hui , Zhang Xiaogang 
Published: April 2019

AbstractLithium‐ion capacitors (LICs) are emerging as one of the most advanced energy storage devices by combining the virtues of both supercapacitor and lithium‐ion battery. The key point of constructing high‐performance LICs is to balance the electrochemical kinetics and capacity mismatch between battery‐type anode and capacitive‐type cathode materials. Herein, a strategy is presented for simultaneous manipulation of a MoS2/N‐doped carbon microspheres anode and hierarchical porous carbon cathode by using polyimide precursor. Owing to the fast lithium diffusion rate, high pseudocapacitive behavior, and expanding the interlayer of the MoS2 composite network architecture, the material can achieve excellent rate capacity and cyclic stability. Hierarchical porous carbon has an ultrahigh specific surface area and superior capacitive behavior. A high‐performance LIC is successfully constructed by using the superior anode and cathode materials. The device can deliver a maximum energy density of 120 Wh kg−1 and keep the capacity retention of 85.5% after 4000 cycles, revealing the competition in advanced energy storage devices. Accordingly, the simultaneous manipulation of metal sulfide and hierarchical porous carbon by the same precursor can be used toward fabricating other ideal electrode structures for energy storage.
Monitoring the riverine pulse: Applying high‐frequency nitrate data to advance integrative understanding of biogeochemical and hydrological processes
Authors: Burns Douglas A. , Pellerin Brian A. , Miller Matthew P. , Capel Paul D. , Tesoriero Anthony J. , Duncan Jonathan M. 
Published: April 2019

AbstractWidespread deployment of sensors that measure river nitrate (NO3−) concentrations has led to many recent publications in water resources journals including review papers focused on data quality assurance, improved load calculations, and better nutrient management. The principal objective of this study is to review and synthesize studies of high‐frequency NO3− data that have aimed to improve understanding of the hydrologic and biogeochemical processes underlying episodic, diel, and long‐term stream NO3− dynamics. Investigations have provided unprecedented detail on hysteresis and flushing patterns during high flow, seasonal variation during baseflow, and responses to multiyear climate variation. Analyses of high‐frequency data have led to notable advances in understanding how climate variation affects spatial and temporal NO3− patterns, especially dry–wet cycles and antecedent moisture. Further advances have been limited by few investigations that include high‐frequency measurements outside the channel and the short duration of many records. High‐frequency data for multiple constituents have provided new insight to the relative roles of hydrology and biogeochemistry as highlighted by studies of the roles of autotrophic uptake, denitrification, riparian evapotranspiration, and temperature‐driven changes in viscosity as drivers of diel patterns. Comparisons of short duration high‐frequency data with long duration low‐frequency data have described similarities and differences in concentration–discharge patterns and highlighted the role of legacy stores. Investigators have applied innovative analysis approaches not previously possible with low‐frequency or temporally irregular data. Future availability of long duration high‐frequency data will provide new insight to processes, resulting in improved conceptual models and a deeper understanding of the role of climate variation.This article is categorized under:

Science of Water > Water Quality
Science of Water > Methods
Water and Life > Nature of Freshwater Ecosystems
Enhanced adsorption and slow release of phosphate by dolomite–alginate composite beads as potential fertilizer
Authors: Huang Yu‐Xi , Liu Meng‐Jie , Chen Shi , Jasmi Irfan Iskandar , Tang Yuanzhi , Lin Shihong 
Published: April 2019

AbstractThe recovery and reuse of phosphorus (P) from wastewater treatment process is a critical and viable target for sustainable P utilization. This study explores a novel approach of integrating ultrafine mineral particles into hydrogel matrixes for enhancing the capacity of phosphate adsorption. Dolomite‐alginate (DA) hydrogel beads were prepared by integrating ball‐milled, ultrafine dolomite powders into calcium cross‐linked alginate hydrogel matrix. The adsorption isotherms followed a Langmuir–Freundlich adsorption model with higher specific adsorption capacity than those reported in literature. The kinetics of phosphate adsorption suggest that the adsorption is diffusion controlled. Investigation of adsorption capacity at different pH showed a maximum adsorption capacity in the pH range of 7–10. Lastly, we demonstrated that the DA beads are capable of slowly releasing most of the adsorbed phosphate, which is an important criterion for them to be an effective phosphorous fertilizer. This study, using DA composite hydrogel as an example, demonstrates a promising strategy of immobilizing ultrafine mineral adsorbents into biocompatible hydrogel matrix for effective recovery of phosphorous resource from wastewater.Practitioner points

Integration of dolomite and alginate hydrogel beads is demonstrated using ball milling.

Ball milling process increases the specific adsorption capacity of dolomite on phosphorus.

Adsorption isotherms, kinetics, and pH effects of the dolomite–alginate beads are investigated.

The dolomite–alginate beads can be used as slow‐release phosphorus fertilizer.
Does It Really Matter? Assessing the Performance Effects of Changes in Leadership and Management Structures in Nordic Higher Education
Authors: Pulkkinen Kirsi , Aarrevaara Timo , Berg Laila Nordstrand , Geschwind Lars , Hansen Hanne Foss , Hernes Helge , Kivistö Jussi , Lind Jonas Krog , Lyytinen Anu , Pekkola Elias , Pinheiro Rómulo , Stensaker Bjørn , Söderlind Johan 
Published: April 2019

AbstractUniversities are public organisations, which operate in a highly institutionalised environment. They are heavily dependent on public resources. As such, universities are susceptible to shifts in governance arrangements but are also far from being passive recipients of reform agendas. They face demands from multiple internal constituencies (academics, administrators, students, managers) and from a variety of external stakeholders. This chapter explores the interplay between governance arrangements resulting from policy shifts and university dynamics. It sets the stage for the book, asking the following research questions: (1) what characterises changes in governance regimes in Nordic universities in the last decade and a half, and (2) what effects have these changes had in the evolution of higher education systems? The chapter takes a comparative approach and identifies similarities and differences across the Nordic countries. This chapter serves as a frame of reference for the book and includes a common methods and data section.
Performance in Higher Education Institutions and Its Variations in Nordic Policy
Authors: Kivistö Jussi , Pekkola Elias , Berg Laila Nordstrand , Hansen Hanne Foss , Geschwind Lars , Lyytinen Anu 
Published: April 2019

AbstractThe need for greater efficiency, productivity and quality in the higher education sector has triggered increased governmental interest towards different mechanisms of accountability, especially evaluation and performance measurement. This interest has developed over a relatively long period of time, but it has now reached its culmination point in many ways. For instance, advances in citation tracking, performance data collection and databases and the professionalisation of evaluative practices and methods have opened new avenues for verifying accountability. This chapter offers definitions for the key concepts used throughout the book, as follows: accountability, evaluation, and performance measurement and management. Each section is followed by a short contextualisation of the concept in Denmark, Finland, Norway and Sweden. The chapter ends with a short discussion about the policy convergence between Nordic countries and the reasons for it.