bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of low velocity impact at different temperatures on hybrid adhesives in aluminium-composite single lap joints
Authors: Yilmaz Musa , Ekrem Mürsel 
Published: November 2024

This study aims to investigate the effect of a small stone impact on aluminum composite adhesive joints used in aircraft after exposure to various temperature conditions. In this context, single lap adhesive joints were prepared using 2024-T3 aluminium alloy sheets and 8-layer carbon fiber-reinforced epoxy hybrid composite sheets, with epoxy adhesive applied to the bonding surfaces. In addition, different types of hybrid adhesives were developed by reinforcing pure epoxy adhesive with various ratios (1%, 3% and 5% by weight) of graphene doped and undoped Nylon 6.6 (N6.6) nanofibers produced by electrospinning method to reduce brittleness. Low-velocity impact tests of 1.04 m/s under five different temperatures (−50, −20, 0, 23 and 50°C) were applied to all single lap adhesion joints produced and tensile tests were applied to the non-failed specimens to examine the loading conditions after low-speed impact. It was determined that approximately 1.5 J of the 3 J energy given by the low- velocity impact was absorbed in common in all samples, while the remaining part was returned and some separation occurred within the adhesion area due to the effect of this impact. While the low- velocity post-impact tensile strength of pure epoxy resin was measured as 2230.3 N at 23°C and 585.15 N at −50°C, the highest values were obtained in N6.6 reinforced epoxy adhesive with 1%GNP additive, which was measured as 3206.39 N at 23°C and 641.82 N at −50°C, and increased by 43.7% and 9.6% for 23°C and −50°C, respectively. In addition, the rupture surfaces of the specimens destroyed by the tensile test were examined by scanning electron microscopy (SEM) for damage analysis.
Spanish Translation, Adaptation and Psychometric Analysis of a Short Version of the Intercultural Sensitivity Scale in Chilean Public Workers
Authors: Martínez-Zelaya Gonzalo , Chavez-Herting David , Guglielmetti-Serrano Florencia 
Published: November 2024

Chile has been facing socio-cognitive, affective and cultural tensions and changes due to the constant increase of the migrant population in Chile over the last two decades. This means that local public policy workers must interact and achieve effective communication with migrant users living in their territories. Intercultural sensitivity is understood as the affective dimension of intercultural communication. This dimension facilitates the awareness that people differ in their behaviors, perceptions and feelings during intercultural communication processes, promoting acceptance and respect towards these differences. The aim of this paper was to analyze the factor structure, psychometric properties and invariance of the Intercultural Sensitivity scale (Chen & Starosta, 2000) in a sample of Chilean workers. The sample consists of 337 workers from five municipalities in two regions of Chile. The sample has a mean age of 42.8 years (SD = 10.4), and 62.9% report being female. To determine the factor structure, an unweighted least squares (ULS) parameter estimation method was used, which is recommended for relatively small sample sizes, as is the case in this study. The overall structure of the original scale, although showing adequate indicators in a confirmatory factor analysis, presented serious conflicts in the covariance matrix used. Therefore, the 5-factor structure seen in other studies is disconfirmed. Because of this, it was decided to construct an abbreviated version, but reducing the limitations encountered during the validation process. The final result is a 4-dimensional structure, corresponding to four of the original dimensions, with a total of 13 items. The goodness-of-fit indices (CFI, TLI, RMSEA and SRMR) had optimal levels. The Manifest and Subtle Prejudice scale was used for its divergent validity, presenting all the dimensions of the instrument, and its total score, inverse and significant correlations with manifest prejudice, subtle prejudice, and total prejudice, as expected.
Innovative Game-Based Teaching Methods for Promoting Nursing Students’ Cultural Competence and Attitudes Toward Refugees: An Explanatory Sequential Mixed Study
Authors: Baysal Ebru , Rodriguez-Arrastia Miguel , Roman Pablo 
Published: November 2024

Introduction: Nursing cultural competence is crucial for enhancing the quality of care for refugees. While innovative game-based teaching methods have been used to foster in a wide range of clinical competences, little is known about its use on refugees’ care. This study aims to evaluate the effect of these methods on nursing students’ cultural competence and attitudes toward refugees. Methodology: An explanatory sequential mixed design was conducted from March to May 2023. Results: One-hundred forty-one nursing students participated. There were no statistically significant differences in total Outgroup Threat Perception Scale and Cultural Competence Assessment Scale scores between the experimental and control groups, pre- or post-intervention. However, students reported increased awareness and empathy for refugee issues. Discussion: The study showed that innovative game-based teaching methods effectively increased nursing students’ awareness of health-related issues faced by refugees. It recommends incorporating transcultural nursing courses into curricula and professional training, with updated content on migration and refugee issues.
Sequential endoscopic treatment for esophageal and gastric variceal bleeding significantly reduces patient mortality and rebleeding rates
Authors: Tao Kong , Shan Xu , He Binbo , Zeng Qingyu , Wu Meirong , Jie Liu , Yuan Wenfeng , Dan Hu , Tao Zhang 
Published: November 2024

Background: Esophageal-gastric variceal bleeding (EGVB) is a serious complication in patients with liver cirrhosis, characterized by high mortality and rebleeding rates. The effect of sequential endoscopic therapy on patient mortality and rebleeding rates remains unclear. Objectives: This study aimed to evaluate the effects of sequential endoscopic therapy on mortality and rebleeding rates in patients with EGVB. Design: In this single-center retrospective study, 373 hospitalized cases of EGVB caused by liver cirrhosis, collected between November 2019 and November 2023, were divided into four groups according to different treatment methods: a sequential endoscopy group, emergency endoscopy group, emergency endoscopy plus transjugular intrahepatic portosystemic shunt (TIPS) group and control group. Methods: Mortality and rebleeding rates were compared among the four groups using statistical analyses. Results: The mortality and rebleeding rates of the sequential endoscopy group (3.7% and 19%, respectively) were significantly lower than those of the emergency endoscopy (22% and 36%, respectively), emergency endoscopy plus TIPS (33% and 28%, respectively), and control groups (33% and 51%, respectively) ( p = 0.013 and p = 0.013, respectively). Conclusion: Sequential endoscopic therapy may significantly reduce the mortality and rebleeding rates of patients with EGVB compared to other conventional treatment strategies. The findings of the study could help develop approaches benefiting EGVB treatment.
Analyses of Xenorhabdus griffiniae genomes reveal two distinct sub-species that display intra-species variation due to prophages
Authors: Heppert Jennifer K. , Awori Ryan Musumba , Cao Mengyi , Chen Grischa , McLeish Jemma , Goodrich-Blair Heidi 
Published: November 2024

Abstract
Background
Nematodes of the genus Steinernema and their Xenorhabdus bacterial symbionts are lethal entomopathogens that are useful in the biocontrol of insect pests, as sources of diverse natural products, and as research models for mutualism and parasitism. Xenorhabdus play a central role in all aspects of the Steinernema lifecycle, and a deeper understanding of their genomes therefore has the potential to spur advances in each of these applications.

Results
Here, we report a comparative genomics analysis of Xenorhabdus griffiniae, including the symbiont of Steinernema hermaphroditum nematodes, for which genetic and genomic tools are being developed. We sequenced and assembled circularized genomes for three Xenorhabdus strains: HGB2511, ID10 and TH1. We then determined their relationships to other Xenorhabdus and delineated their species via phylogenomic analyses, concluding that HGB2511 and ID10 are Xenorhabdus griffiniae while TH1 is a novel species. These additions to the existing X. griffiniae landscape further allowed for the identification of two subspecies within the clade. Consistent with other Xenorhabdus, the analysed X. griffiniae genomes each encode a wide array of antimicrobials and virulence-related proteins. Comparative genomic analyses, including the creation of a pangenome, revealed that a large amount of the intraspecies variation in X. griffiniae is contained within the mobilome and attributable to prophage loci. In addition, CRISPR arrays, secondary metabolite potential and toxin genes all varied among strains within the X. griffiniae species.

Conclusions
Our findings suggest that phage-related genes drive the genomic diversity in closely related Xenorhabdus symbionts, and that these may underlie some of the traits most associated with the lifestyle and survival of entomopathogenic nematodes and their bacteria: virulence and competition. This study establishes a broad knowledge base for further exploration of not only the relationships between X. griffiniae species and their nematode hosts but also the molecular mechanisms that underlie their entomopathogenic lifestyle.
Correlation between intestinal microbiota and urolithin metabolism in a human walnut dietary intervention
Authors: Liu Huijia , Birk John W. , Provatas Anthony A. , Vaziri Haleh , Fan Nuoxi , Rosenberg Daniel W. , Gharaibeh Raad Z. , Jobin Christian 
Published: November 2024

AbstractThis study is to investigate the relationship between the intestinal microbiota and urine levels of the ellagic acid-derived polyphenols, the urolithins, in a cohort of subjects following a three-week walnut dietary intervention. We longitudinally collected fecal and urine samples from 39 subjects before and after walnut consumption (2 oz per day for 21 days). 16S RNA gene sequencing was performed on fecal DNA to study the association between microbiota composition and the levels of nine urolithin metabolites, which were measured using UHPLC/Q-TOF–MS/MS. Fecal microbial composition was found to be significantly different between pre- and post-walnut intervention (beta diversity, FDR-p = 0.018; alpha diversity, p = 0.018). Roseburia, Rothia, Parasutterella, Lachnospiraceae UCG-004, Butyricicoccus, Bilophila, Eubacterium eligens, Lachnospiraceae UCG-001, Gordonibacter, Paraprevotella, Lachnospira, Ruminococcus torques, and Sutterella were identified as the 13 most significantly enriched genera after daily intake of walnuts. We observed 26 genera that were significantly associated with 7 urolithin metabolites, with 22 genera positively correlating after walnut supplementation (FDR-p ≤ 0.05). PICRUSt analysis showed that several inferred KEGG orthologs were associated with 4 urolithin metabolites after walnut intake. In this study, we found that walnut supplementation altered urolithin metabolites, which associates with specific changes in bacterial taxa and inferred functional contents.
Factors affecting emergency medical dispatchers decision making in stroke calls – a qualitative study
Authors: Jamtli Bjørn , Svendsen Edel Jannecke , Jørgensen Trine Møgster , Kramer-Johansen Jo , Hov Maren Ranhoff , Hardeland Camilla 
Published: November 2024

Abstract
Objectives
Emergency Medical Communication Centers (EMCC) have a key role in the prehospital chain-of-stroke-survival by recognizing stroke patients and reducing prehospital delay. However, studies on EMCC stroke recognition report both substantial undertriage and overtriage. Since mis-triage at the EMCC challenges the whole chain-of-stroke-survival, by occupying limited resources for non-stroke patients or failing to recognize the true stroke patients, there is a need to achieve a more comprehensive understanding of the dispatchers’ routines and experiences. The aim of this study was to explore factors affecting EMCC dispatcher’s decision-making in stroke calls.

Materials and methods
A qualitative exploratory study, based on individual semi-structured interviews of 15 medical dispatchers from EMCC Oslo, Norway. Interviews were conducted during August and October 2022 and analyzed using the principles of thematic analysis.

Results
We identified four themes: [1] Pronounced stroke symptoms are easy to identify [2]. Non-specific neurological symptoms raise suspicion of acute stroke but are difficult to differentiate from other medical conditions [3]. Consistent use of the Criteria Based Dispatch (CBD) protocol may increase EMCC overtriage [4]. Contextual conditions at EMCC can affect dispatchers’ decision-making process and the ability for experiential learning.

Conclusions
Medical dispatchers at the EMCC perceive vague and non-specific stroke symptoms, such as dizziness, confusion or altered behaviour, challenging to differentiate from symptoms of other less time-critical medical conditions. They also perceive the current CBD protocol in use as less supportive in assessing such symptoms. High workload and strict EMCC response time interval requirements hinder the gathering of essential patient information and the ability to seek guidance in cases of doubt, potentially exacerbating both EMCC undertriage and overtriage. The absence of feedback loops and other strategies for experiential learning in the EMCC hampers the medical dispatcher’s ability to evaluate their own assessments and improve dispatch accuracy.
The relationship and heterogeneity of family participation and social participation among older adults: from an intersectionality perspective
Authors: Liu Yan 
Published: November 2024

AbstractParticipation in late life has been studied as a component of active aging. To effectively promote late-life participation, the study explored the relationship and heterogeneity between two forms of participation among older adults—familial participation and societal participation. This paper utilizes data from the 2020 China Longitudinal Aging Society Survey (CLASS) to examine the relationship between familial participation and societal participation among older Chinese adults. Linear regression results indicate that familial participation can facilitate societal participation among older adults. The MAIHDA model results suggest variations in familial and societal participation among older adults in different social positions. Specifically, older women with higher socioeconomic status and better health have higher levels of familial and societal participation, whereas older men with lower socioeconomic status and health have the lowest levels of participation. Socioeconomic status is the most significant factor contributing to participation disparities among different groups, and older adults with disadvantaged health status experience a compounding effect of multiple disadvantages. The research findings hold significant implications for formulating policies aimed at enhancing the participation of marginalized older adults, ultimately contributing to the realization of active aging.
“There’s no us vs. them, it’s just us”: a creative approach to centring lived experience within the AVATAR2 trial
Authors: Owrid Oliver , Richardson Leonie , Allan Stephanie , Grant Amy , Gogan Sarah , Hamilton Nicholas , Yanga Francis , Sirey Nicola , Syrett Suzy , Garety Philippa , Craig Tom , Clancy Moya , Pinfold Vanessa , Miller Lucy , Ward Thomas , Edwards Clementine 
Published: November 2024

AbstractThis article describes a Patient and Public Involvement (PPI) led creative workshop space held within a clinical trial of a talking therapy for distressing voices (AVATAR2). PPI adds significant value to clinical research and ensures the work is meaningful to patients and their supporters. However, known issues include tokenism, a common power imbalance between PPI colleagues and researchers and a lack of opportunity for PPI to shape the research. PPI has played a key role at all stages of the AVATAR2 trial, including design, recruitment of staff and participants, data collection, analysis, and dissemination. An active and creative group of people was established, with over 30 members flexibly involved across all four sites. PPI group members were from diverse backgrounds, with lived experience of mental health conditions and recovery, and including carers. During this work, PPI colleagues identified that they would value a creative space which would help to promote the study but extend beyond an exclusive focus on trial deliverables. A regular creative workshop was established to support PPI colleagues in their creative work, including material such as poetry, blogs, art and podcasts. PPI colleagues and trial staff have cowritten a reflective piece to share their experiences on the impact of the creative workshops, organised into four themes. We found the workshops to be a powerful tool for forging relationships among trial staff and PPI colleagues, while also fostering personal development. We reflected on how the workshops built up the confidence of attendees and supported demanding trial activities such as public speaking. Finally, we discussed the impact of the workshops on wider trial culture, by upholding the values of the team and challenging the status quo.
Socioeconomic deprivation and perinatal anxiety: an observational cohort study
Authors: Best Catherine , Ayers Susan , Sinesi Andrea , Meades Rose , Cheyne Helen , Maxwell Margaret , McNicol Stacey , Williams Louise R , Alderdice Fiona , Jomeen Julie , Shakespeare Judy ,   MAP Study Team, Constantinou Georgina , Gilbody Simon , Hann Agnes , Holly Jennifer , Howard Grace , Hutton Una , Leonard Rachael , Salmon Debra , Uddin Nazihah , Walker James , White Anna , Yuill Cassandra 
Published: November 2024

Abstract
Background
Women from areas of social deprivation and minority ethnic groups are more likely to experience poor physical health and have higher rates of mental health problems relative to women from less socially disadvantaged groups. However, very little research has examined this in relation to perinatal anxiety. The current study aims to determine prevalence, risk factors and desire for treatment for perinatal anxiety in three regions of the UK with diverse regional characteristics.

Methods
Women completed measures of anxiety in early, mid-, late-pregnancy and postpartum. Participants were included from three regions of the UK: Region 1 = North East England & North Cumbria n = 512; Region 2 = London North Thames n = 665; Region 3 = West Midlands n = 705.

Results
Prevalence of perinatal anxiety was lower in Region 1 (OR 0.63 95% CI 0.45 to 0.89) and Region 2 (OR 0.72 95% CI 0.52 to 0.98) relative to Region 3. Analysis showed the effect of neighbourhood socioeconomic deprivation on perinatal anxiety differed by region. In more affluent regions, living in a deprived neighbourhood had a greater impact on perinatal anxiety than living in a deprived neighbourhood in a deprived region. Other factors associated with risk of anxiety in the perinatal period included physical health problems and identifying as being from ‘mixed or multiple’ ethnic groups.

Conclusions
Neighbourhood deprivation relative to regional deprivation is a better predictor of perinatal anxiety than either regional deprivation or neighbourhood deprivation alone. Women of mixed ethnic backgrounds and women with physical health problems may warrant more attention in terms of screening and support for perinatal anxiety. Self-reported desire for treatment was found to be low.
Why are organisational approvals needed for low-risk staff studies in the UK? Procedures, barriers, and burdens
Authors: Dunleavy Lesley , Board Ruth , Coyle Seamus , Dickman Andrew , Ellershaw John , Gadoud Amy , Halvorsen Jaime , Hulbert-Williams Nick , Lightbody Liz , Mason Stephen , Nwosu Amara Callistus , Partridge Andrea , Payne Sheila , Preston Nancy , Swash Brooke , Taylor Vanessa , Walshe Catherine 
Published: November 2024

Abstract
Background
Health care staff should be given the opportunity to participate in research, but recruiting clinicians via their employing organisation is not always straightforward or quick in the UK. Unlike many countries outside the UK, very low-risk survey, interview or focus group studies can be subject to some of the same governance approval procedures as interventional studies. An exemplar study carried out by the NIHR funded Palliative Care Research Partnership North West Coast is used to highlight the challenges still faced by researchers and health care organisations when setting up a low-risk staff study across multiple NHS and non-NHS sites.

Methods
A study database was created and information was collected on the first point of contact with the clinical site, Health Research Authority (HRA) and local organisational approval times, time from trust or hospice agreement to the first survey participant recruited and overall site survey recruitment numbers. Descriptive statistics (median, range) were used to analyse these data.

Results
Across participating NHS trusts, it took a median of 147.5 days (range 99–195) from initial contact with the local collaborator to recruitment of the first survey participant and hospice sites mirrored these lengthy timescales (median 142 days, range 110–202). The lengthiest delays in the HRA approval process were the period between asking NHS trusts to assess whether they had capacity and capability to support the research and them granting local agreement. Local approval times varied between trusts and settings which may indicate organisations are applying national complex guidance differently.

Conclusions
There is the potential for HRA processes to use more NHS resources than the research study itself when recruiting to a low-risk staff study across multiple organisations. There is a need to reduce unnecessary administrative burden and bureaucracy to give clinicians and research staff more opportunities to participate in research, and to free up NHS R&D departments, research nurses and clinicians to focus on more demanding and patient focused research studies. Hospices need standardised guidance on how to assess the risk of being involved in low-risk research without adopting the unnecessarily complex systems that are currently used within the NHS.