bluuebunny/crossref_metadata_2025_split huggingface dataset:
Squamous cell carcinoma of buccal mucosa: An analysis of prognostic factors
Authors: Bobdey Saurabh , Sathwara Jignasa , Jain Aanchal , Saoba Sushma , Balasubramaniam Ganesh 
Published: September 2019

Abstract
Introduction: Carcinoma of the buccal mucosa is the most common oral cavity cancer in the Indian subcontinent. The aim of this study was to analyze the outcome and evaluate prognostic factors in surgically treated buccal mucosa squamous cell carcinoma (BMSCC) patients. Materials and Methods: A retrospective study was performed by reviewing the medical records of 409 pathologically proven buccal mucosa cancer patients, who were diagnosed and surgically treated in Tata Memorial Hospital between January 1, 2006, and December 31, 2008. Results: The overall 5-year survival of the cohort was found to be 54.1%. The stage-wise survival rate for tumor, node, metastasis (TNM) Stage I, II, III, and IV patients was found to be 85.2%, 82.9%, 56.3%, and 42.6% (P < 0.00), respectively. On multivariate Cox proportional hazard analysis, the presence of comorbidity, histological tumor size, pathological lymph node status, tumor differentiation, perineural invasion, and extracapsular spread were found to be independently associated with overall survival. Conclusion: BMSCC is an aggressive malignant tumor. In addition to TNM classification, other clinical and pathological factors also have a significant role in BMSCC prognostication. Hence, there is a need to move beyond TNM and develop a more inclusive, flexible, and easy to use prognostic system.
Role of Silicone Stenting in Endoscopic Dacryocystorhinostomy: A Comparative Study
Authors: Ahmad Shahzad , Pant Bhawana 
Published: September 2019

ABSTRACTObjectiveTo evaluate the role of using silicone stent in endoscopic dacryocystorhinostomy (DCR) and compare the results with endoscopic DCR without silicone stenting.DesignProspective study, interventional type, randomized design and comparative analysis.Materials and methodsThe study was done in Department of Otorhinolaryngology, Government Medical College and Dr Susheela Tiwari Hospital, Haldwani, Uttarakhand. We included 30 patients in the study presenting with epiphora with or without mucocele and congenital cases of dacryocystitis and nasolacrimal duct (NLD) blockage were included in the study.All patients were divided into two groups. First one undergoing endoscopic DCR and silicone stent was used in all cases and second one underwent endoscopic DCR and no stent was used. Postoperative assessment was carried out at the end of 1st, 3rd, 6th and 10th week and the role of silicone stent was subjected to compare.ResultUse of silicone stent was not improving the results and risk of failure of the surgery had increased with stent due to granulation formation in the lacrimal sac region.Apart from that, foreign body reactions in the form of irritation, pain were seen with stent. It also added the cost of surgery without giving much benefit to the patient.How to cite this articleAhmad S, Pant B. Role of Silicone Stenting in Endoscopic Dacryocystorhinostomy: A Comparative Study. Int J Adv Integ Med Sci 2016;1(1):4-6.
Intraoral Schwannoma: A Rare Case Report
Authors: Agrawal Ranjan , Bhardwaj Prashant , Srivastava Abhinav 
Published: September 2019

ABSTRACT
Schwannomas or neurilemmomas are benign, encapsulated tumor arising from nerve sheath cells. Intracranial Schwannomas are most common with rare occurrence in the extracranial region. It rarely occurs in the floor of the mouth with very few cases reported. We present a rare case report of Schwannoma of the floor of the mouth, thereby highlighting the consideration of this rare entity as one of the differential diagnosis in cases who present to us with swelling of the floor of the mouth and also the importance of immunohistochemistry in coming to the diagnosis.

How to cite this article
Srivastava A, Mohan C, Bhardwaj P, Agrawal R. Intraoral Schwannoma: A Rare Case Report. Int J Adv Integ Med Sci 2016;1(1):20-22.
Complex Odontoma (Intraosseous type) Associated with Mandibular Impacted Permanent Second Molar
Authors: Gangwar Anil , Pant Bhawna , Garkoti PD 
Published: September 2019

ABSTRACT
The most common odontogenic tumor is odontoma comprising 22% of all the cases. They show no gender predilection, are most often diagnosed in the second decade of life. They are preferentially located in the upper maxilla, particularly in the anterior sector. These are of two types complex and compound. Complex odontoma is a less prevalent than compound (1:2). Their apparent eruption in the oral cavity is rare. We hereby report a rare case of complex odontoma (intraosseous type) associated with impacted lower permanent second molar. These lesions are mostly asymptomatic and constitute casual finding on X-ray indicated for other reasons. The most common clinical manifestation is absence of impacted tooth and the presence of tumor. Treatment consists of surgical removal of tumor with impacted tooth. The prognosis is very good with least tendency toward relapse.

How to cite this article
Gangwar A, Pant B, Garkoti PD. Complex Odontoma (Intraosseous type) Associated with Mandibular Impacted Permanent Second Molar. Int J Adv Integ Med Sci 2016;1(1):32-35.
Road Traffic Accidents in India
Authors: Sharma SM 
Published: September 2019

ABSTRACT
Road traffic accidents (RTAs) result in tremendous loss of lives and prolonged morbidity besides causing sufferings to relatives and friends. Loss of lives and useful working hours inflict heavy damage to a nation's economic activity, loss of breadwinner to family, and deprivation of family bond of love and security. Increasing traffic accidents and subsequent trauma creates heavy burden on our scarce funds and already overburdened hospitals. Road traffic accidents are one of the major causes of death and illness which is preventable. There is tremendous rise in RTAs due to increase in vehicular volume on our roads, incredible speeding of the vehicles, poor driving skills, drunk driving, bad roads, poor traffic control, and lack of public awareness, rampant indiscipline, incompetent authorities and lack of implementation of existing laws to tackle the menace of disrespect to law and rules. The solution to the problem lies in reducing the volume of traffic on roads by instituting efficient public transport system all over, like the one prevalent in advanced nations of the world, honest road engineering, universal education and training of all citizens in driving, creating awareness about road safety precautions, enforcing strict punishments upon offenders indulging in drunk driving and crossing the speed limits, and regulating control of traffic on highways and accident-prone areas.

How to cite this article
Sharma SM. Road Traffic Accidents in India. Int J Adv Integ Med Sci 2016;1(2):57-64.
A Study of Fossa Vel Spina of North Indian Crania in Rohilkhand Region
Authors: Husain Zaidi Sayeed Haider , Kumar Sarangdhar , Debbarma Soubhik 
Published: September 2019

ABSTRACT
There are controversial statements in the available literature regarding the variations in the trochlear foveae or fossae and spines. This study was undertaken especially to know about the variations in Indian skulls in Western Uttar Pradesh. A total of 25 skulls from the anatomy museum of Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh, were studied.
In 18 (72%) cases, the trochlear foveae were present on both sides. In 3 (12%) cases, bilateral trochlear spines were present. Spines were present only on one side in 3 (12%) cases. We also noticed that in 1 (4%) case, both the spines and foveae were absent bilaterally.

How to cite this article
Prasad NK, Husain ZSH, Kumar S, Debbarma S. A Study of Fossa Vel Spina of North Indian Crania in Rohilkhand Region. Int J Adv Integ Med Sci 2016;1(2):65-66.
Brugia malayi in Cervical Lymph Node Aspirate: A Rare Case Report
Authors: Srivastava Abhinav , Kumar Shivesh , Agarwal Ranjan 
Published: September 2019

ABSTRACT
Filariasis is endemic worldwide with the main focus in the tropical areas. Reported cases of filarial lymphadenopathy are caused by Wuchereria bancrofti, which is limited to the groin, the femoral triangle, and axilla, causing lymphedema of lower and upper limbs, and is usually diagnosed clinically and by the presence of microfilaria in peripheral blood smear. We are reporting an unusual case of cervical lymphadenitis, which on fine needle aspiration cytology (FNAC) showed microfilaria of a rare species, Brugia malayi. The purpose of this article is to make clinicians aware of this rare disease as one of the differential diagnoses of cervical lymphadenopathy in an endemic country like India.

How to cite this article
Srivastava A, Mohan C, Kumar S, Agarwal R. Brugia malayi in Cervical Lymph Node Aspirate: A Rare Case Report. Int J Adv Integ Med Sci 2016;1(2):79-80.
A Case of Secondary Amenorrhea as a Result of Cervical Atresia Postdelivery
Authors: Khan Shabina , Mukherjee Shobha , Amrin Sana , Jain Usha 
Published: September 2019

ABSTRACTSecondary cryptomenorrhea is a rare disorder and results due to adhesion formation postdelivery and puerperal sepsis. We report such a case who presented as amenorrhea and progressive pain in the abdomen postdelivery.How to cite this articleAmrin S, Mukherjee S, Khan S, Jain U. A Case of Secondary Amenorrhea as a Result of Cervical Atresia Postdelivery. Int J Adv Integ Med Sci 2016;1(2):86-87.
Den multimodala sakprosan
Authors: Ledin Per , Nyström Höög Catharina , Tønnesson Johan L. , Westberg Gustav 
Published: September 2019

Alla sakprosatexter är multimodala, och denna artikel diskuterar relationen mellan sakprosaforskning och multimodalitetsforskning. Artikeln adresserar två frågor: Hur kan forskning om multimodalitet och sakprosa stimulera varandra? och Hur förhåller sig nordisk sakprosaforskning till en vidare multimodal forsknings-tradition? För att besvara dessa frågor tecknar artikeln multimodalitetstraditionens utveckling samt härleder sakprosabegreppets ursprung. I ljuset av såväl äldre som nutida sakprosaforskning argumenterar artikeln för att sakprosabegreppets multimodala potential huvudsakligen ligger i förledet sak­ eftersom det riktar ljuset mot textens roll som ett yttrande om verkligheten inom en institution. Således argumenterar artikeln att samspelet mellan verbalspråket och andra semiotiska resurser bör stå i centrum vid studiet av sakprosa, oberoende av om det handlar om ett samspel mellan verbalspråk och t.ex. visuella, rumsliga eller auditiva resurser. Detta pekar slutligen på nödvändigheten i att uppmärksamma hur olika affordanser – dvs. möjligheter och begränsningar – i olika semiotiska material används i olika kontexter. Därmed blir också efterledet prosa relevant, eftersom de riktar uppmärksamheten mot kvaliteter i uttrycket. AbstractAll non-fictional prose (“sakprosa” in the Scandinavian languages) is multimodal, and this paper discusses how the study of non-fictional prose relates to research on multimodality. In doing so, the paper answers two research questions: How can research on non-fictional prose and multimodality enrich each other? and How does Nordic research on non-fictional prose relate to the wider field of multi-modality? In order to answer these questions, the trajectories of the multimodality tradition are outlined as well as the genealogy of the concept sakprosa. Drawing on older as well as contemporary Nordic research on non-fictional prose, the article argues that the prefix sak­ ­has at its potential to inform multimodality research, primarily because it conceptualizes text as an utterance about the reality within a specific institution. Accordingly, the article argues that the interplay between language and other semiotic (e.g. visual; spatial; auditive) modes needs to be fore fronted in the study of non-fictional prose. This, finally, points to the importance of paying attention to how different affordances, i.e. the possibilities and constraints in different semiotic materials, are employed in different contexts. Thus, the suffix prose also becomes relevant, as it draws attention to the qualities of the expression.
Correlation of ROS1 Immunohistochemistry With ROS1 Fusion Status Determined by Fluorescence In Situ Hybridization
Authors: Huang Richard S. P. , Smith Derek , Le Catherine H. , Liu Wen-Wei , Ordinario Ellen , Manohar Chitra , Lee Michael , Rajamani Jaya , Truong Huan , Li Jing , Choi Cindy , Li Jingchuan , Pati Amrita , Bubendorf Lukas , Buettner Reinhard , Kerr Keith M. , Lopez-Rios Fernando , Marchetti Antonio , Marondel Ivonne , Nicholson Andrew G. , Öz Ayşim Büge , Pauwels Patrick , Penault-Llorca Frederique , Rossi Giulio , Thunnissen Erik , Newell Amy Hanlon , Pate Greg , Menzl Ina 
Published: September 2019

Context.—
The ability to determine ROS1 status has become mandatory for patients with lung adenocarcinoma, as many global authorities have approved crizotinib for patients with ROS1-positive lung adenocarcinoma.

Objective.—
To present analytical correlation of the VENTANA ROS1 (SP384) Rabbit Monoclonal Primary Antibody (ROS1 [SP384] antibody) with ROS1 fluorescence in situ hybridization (FISH).

Design.—
The immunohistochemistry (IHC) and FISH analytical comparison was assessed by using 122 non–small cell lung cancer samples that had both FISH (46 positive and 76 negative cases) and IHC staining results available. In addition, reverse transcription–polymerase chain reaction (RT-PCR) as well as DNA and RNA next-generation sequencing (NGS) were used to further examine the ROS1 status in cases that were discrepant between FISH and IHC, based on staining in the cytoplasm of 2+ or above in more than 30% of total tumor cells considered as IHC positive. Here, we define the consensus status as the most frequent result across the 5 different methods (IHC, FISH, RT-PCR, RNA NGS, and DNA NGS) we used to determine ROS1 status in these cases.

Results.—
Of the IHC scoring methods examined, staining in the cytoplasm of 2+ or above in more than 30% of total tumor cells considered as IHC positive had the highest correlation with a FISH-positive status, reaching a positive percentage agreement of 97.8% and negative percentage agreement of 89.5%. A positive percentage agreement (100%) and negative percentage agreement (92.0%) was reached by comparing ROS1 (SP384) using a cutoff for staining in the cytoplasm of 2+ or above in more than 30% of total tumor cells to the consensus status.

Conclusions.—
Herein, we present a standardized staining protocol for ROS1 (SP384) and data that support the high correlation between ROS1 status and ROS1 (SP384) antibody.
A Clinicopathologic and Molecular Update of Pancreatic Neuroendocrine Neoplasms With a Focus on the New World Health Organization Classification
Authors: Fang Jiayun M. , Shi Jiaqi 
Published: September 2019

Context.—
According to the 2017 World Health Organization classification, pancreatic neuroendocrine neoplasms (PanNENs) include a new category of pancreatic neuroendocrine tumor, grade 3, which is often difficult to differentiate from pancreatic neuroendocrine carcinoma. However, pancreatic neuroendocrine tumor grade 3 and pancreatic neuroendocrine carcinoma are distinct entities with very different clinical presentation, prognosis, and therapeutic strategies. Recent discoveries on the molecular characteristics of pancreatic neuroendocrine tumors also play an essential role in the pathologic differential diagnosis of PanNENs. In addition, the histopathologic varieties of PanNENs bring in many differential diagnoses with other pancreatic neoplasms, especially acinar cell carcinoma, solid pseudopapillary neoplasm, and ductal adenocarcinoma.

Objective.—
To provide a brief update of the World Health Organization classification; the clinical, histopathologic, immunohistochemical, and molecular characteristics; and the differential diagnoses and biological behavior of PanNENs.

Data Sources.—
Analysis of the pertinent literature (PubMed) and authors' clinical practice experience based on institutional and consultation materials.

Conclusions.—
The evolving clinical, histopathologic, immunohistochemical, and molecular features of PanNENs are reviewed. Important differential diagnoses with other neoplasms of the pancreas are discussed.
STUDY OF DILUTED SOLUTIONS OF PORPHYRIN-CONTAINING POLYMERIC SYSTEMS BASED ON POLY-4-VINYLPYRIDINE
Authors: Petrova Maria V. , Аgeeva Тatiana А. , Rodina Sofia S. , Koifman Oscar I. 
Published: September 2019

The dynamic light scattering method was used to determine the diffusion coefficients and hydrodynamic radius of particles in diluted dimethylformamide solutions of poly-4-vinylpyridine, polystyrene, styrene and 4-vinylpyridine copolymers with different comonomer compositions and poly-4-vinylpyridine modified by zinc meso-tetraphenilporphrine. The temperature range was from 20 °C to 25 °C. The copolymers were obtained in different conditions - by thermal and microwave heating. In order to determine the optimal conditions for the behavior of macromolecular reactions involving these polymers, diluted solutions of all samples were studied by the viscometric method. For these systems, a solvent of appropriate quality was selected, the structure of the solution was studied, the interaction of the solvent with the polymer was evaluated, the parameters of the macromolecular ravel were calculated: characteristic viscosities, Huggin’s constants, root-mean-square distances between the ends of the chains and the specific indicator of the system taking into account the molecular weight of the polymers was presented. It is shown, that the values of characteristic viscosity fall with increasing temperature, the Huggin’s constant, on the contrary increases. These data indicate that the "quality" of the solvent for the systems under study is deteriorating, that is, the tangle of macromolecules in dimethylformamide shrinks with increasing temperature. This behavior is typical for systems with a lower critical temperature of dissolution. The introduction of the porphyrin fragment into the polymer macromolecule loosens the macromolecular coil, but does not change the behavior of the system in the solution as a whole. The results obtained by the quasi-elastic light scattering method are consistent with the data obtained by the viscometric method. The surface morphology and elemental composition of poly-4-vinylpyridine and coordination-related porphyrin polymers on its basis were studied by scanning electron microscopy.
PROMOTING EFFECT OF PYRIDINE BASES ON INDIRECT ELECTROCHEMICAL OXIDATION OF ALCOHOLS
Authors: Kashparova Vera P. , Ilchibaeva Irina B. , Smirnova Nina V. , Kagan Efim Sh. , Shubina Elena N. , Zhukova Irina Yu. 
Published: September 2019

The effect of pyridine on the reaction of indirect electrochemical oxidation of alcohols to carbonyl compounds by the catalytic system of 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxyl - iodine in a two-phase aqueous-organic medium: methylene chloride - an aqueous solution of sodium bicarbonate (pH 8.6) was studed. It was shown that the process of indirect electrochemical oxidation of alcohols is accelerated by 1.5–2 times in the presence of pyridine. The corresponding aldehydes and ketones are formed with a high yield (75-95%) after passing 2-2.2 F of electricity. Additionally, the effect of other pyridine bases (2,6-lutidine, 4-acetylpyridine, 2-methyl-5-ethylpyridine, collidine) on indirect electrochemical oxidation of alcohols was studied using the example of 1-octanol. The absence of significant differences in the promoting action of pyridine bases was established and it was shown that in all cases the octanol is obtained with a high yield and coulombic efficiency (90-95 %). A mechanism for the reaction of indirect electrochemical oxidation of alcohols with the participation of 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxyl and pyridine bases is proposed. The promoting effect of pyridine (or other pyridine bases) consists in the formation of an intermediate complex between the base, oxoammonium cation and alcohol. The formation of the complex facilitates the rapid transfer of the proton from the alcohol to the pyridine base and the hydride ion to the oxoammonium cation with the formation of the corresponding carbonyl compound from the alcohol. The preparative methods for the electrochemical synthesis of carbonyl compounds from aliphatic, cyclic, aromatic, heterocyclic alcohols including synthesis of 2,5-diformylfuran from 5-hydroxymethylfurfuralin using the two-phases catalytic system of 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxyl - potassium iodide in the presence of pyridine bases, are proposed.
Avant les inondations
Authors: Denton David , Izaguirre Dario , Casault Kathryn , Izaguirre-Falardeau Gabrielle 
Published: September 2019

Les grands projets hydroélectriques peuvent avoir des effets dévastateurs sur les peuples autochtones. L’évaluation et l’atténuation des impacts archéologiques, très souvent planifiées et réalisées sans un engagement réel des autochtones, peuvent être considérées par les communautés concernées comme ayant des impacts négatifs. Comment l’archéologie, réalisée dans ce contexte, peut-elle mieux répondre aux objectifs et aux préoccupations des communautés ? Les auteurs du présent article décrivent un programme d’archéologie réalisé entre 2003 et 2009 par les Cris d’Eeyou Istchee sur deux projets hydroélectriques connexes, en mettant l’accent sur les efforts déployés par les Cris pour préserver leur patrimoine culturel à travers le Programme sur l’archéologie et le patrimoine culturel (PAPC). Dans ce programme, l’archéologie n’était qu’un élément dans un ensemble d’activités visant à constituer des archives culturelles et historiques sur les zones touchées et à réaliser des programmes éducatifs destinés aux jeunes Cris, ainsi qu’à célébrer et commémorer ces terres. Le PAPC comportait un degré élevé d’engagement et de contrôle de la part de la communauté ainsi qu’une collaboration étroite avec les aînés et les utilisateurs des terres cris. Les connaissances cries et les méthodes axées sur la communauté ont été essentielles pour déterminer les résultats. Dans cette optique, cet article examine les défis auxquels le PAPC a été confronté et les résultats obtenus, pour conclure que de tels projets peuvent à la fois améliorer la qualité scientifique de la recherche archéologique et, parallèlement, au moins timidement, promouvoir la guérison de la communauté et la reconnexion avec la terre et les traditions ancestrales.
L’accessibilité aux aires de jeux dans les parcs de la Communauté métropolitaine de Montréal
Authors: De Alvarenga Bernardo , Apparicio Philippe , Séguin Anne-Marie 
Published: September 2019

Notre objectif, dans cet article, est de vérifier l’existence d’iniquités environnementales en termes d’accessibilité aux aires de jeux sur le territoire de la Communauté métropolitaine de Montréal pour les enfants, les familles monoparentales, les personnes à faible revenu et les minorités visibles. Deux indicateurs d’accessibilité spatiale sont calculés : une mesure de proximité et une mesure de disponibilité basée sur l’offre et la demande d’aires de jeux. La cartographie des deux indicateurs démontre que, dans les banlieues, ces populations résident plus loin de l’aire de jeux la plus proche (souvent à plus 750 m) qui est par ailleurs faiblement saturée (peu d’utilisateurs potentiels dans un rayon de 1000 m) alors que, dans le centre de l’agglomération de Montréal, les enfants résident à proximité d’une aire de jeux (souvent à moins de 500 m), mais qui est potentiellement saturée. Les résultats des régressions démontrent l’absence d’iniquités flagrantes pour les quatre groupes de population. Toutefois, la population à faible revenu a une accessibilité plus limitée alors que les familles monoparentales bénéficient d’une meilleure accessibilité.