bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multidisciplinary tumor boards in oral cavity cancer: survival effect due to balancing guideline adherence and treatment delays
Authors: Burkhardt Valentin , El-Shabrawi Katharina , Riemann Sarah , Voss Pit , Becker Christoph 
Published: November 2024

ObjectivesThe purpose of the study was to assess the impact of a pretherapeutic Multidisciplinary Tumor Board (MTB) presentation on the prognosis and treatment outcomes in patients with primary oral cavity carcinoma.Materials and methodsThis single-center study included 630 patients diagnosed with oral cavity carcinoma treated between 2010 and 2020. The study cohort was divided in a group with and without pretherapeutic MTB presentation. Data on patient demographics, tumor characteristics, treatment and the time to treatment initiation (TTI) were collected retrospectively.ResultsPrimary findings revealed no significant difference in 3-year survival rate (3-YSR) and 3-year disease-free survival rate (3-YDFSR) for the non-MTB and MTB group. The 3-YSR was 73.1% in the non-MTB group and 67.1% in the MTB group (p = 0.112). The 3-YDFSR was 73.8% in the non-MTB group and 76.5% in the MTB group (p = 0.447). Estimated mean 5-year survival (5-YS) and 5-year disease-free survival in (5-YDFS) did not differ significantly between both groups, across the UICC stages I-IV, as well as for the entire cohort. The TTI was significantly longer in the MTB group (33.5 days, CI: 31.3;35.7) compared to the non-MTB group (20.1 days, CI: 17.9;22.4, p &lt; 0.001). The MTB group adhered more frequently to the national guidelines (68% vs. 79.6%, p &lt; 0.01).ConclusionThe results demonstrate both positive and negative side effects of the MTB presentation in patients with oral cavity cancer. Further multicenter studies will be required to assess the impact of TTI and adherence to guidelines on the survival of oral cavity cancer patients.
Clinical efficacy of open palmar approach combined with distal radial cancellous bone transplantation and internal fixation in the treatment of scaphoid nonunion
Authors: Li Gang , Li Rui , Long Jafeng , Ou Xuehai , Shi Shaoyan 
Published: November 2024

BackgroundTo investigate the clinical efficacy of the open palmar approach combined with distal radial cancellous bone transplantation and internal fixation in the treatment of scaphoid nonunion.MethodsFrom March 2019 to March 2022, our center conducted a clinical observation on 19 patients with scaphoid nonunion, including 14 males and 5 females, aged 18–63 years, with an average age of (43.5 ± 15.5) years. The surgical approach involved open palmar access combined with distal radial cancellous bone transplantation and internal fixation, followed by three months of immobilization with a splint. Postoperative x-ray examinations were performed at 6 months to observe bone graft healing and functional recovery.ResultsFollow-up of the 19 patients ranged from 6 to 24 months, with an average of 18 months. All patients achieved bony union, with an average healing time of 6 months. Postoperatively, wrist joint function was assessed using the modified Mayo wrist joint function scoring criteria: excellent in 15 cases, good in 2 cases; an excellent and good rate of 89.5%.ConclusionThe open palmar approach combined with distal radial cancellous bone transplantation and internal fixation is effective in treating scaphoid nonunion. The procedure is minimally invasive, allowing complete exposure of the fractured end of the scaphoid and the distal radius through the same incision. It facilitates easy cleaning of the fracture end, as well as convenient bone harvesting, grafting, and internal fixation. The postoperative efficacy is reliable, demonstrating significant advantages in the treatment of scaphoid nonunion.
Effectiveness of the RB51 vaccine in controlling brucellosis in adult beef cows
Authors: Fernandes Carlos Antônio de Carvalho , Pereira Gustavo Henrique Souza , Pereira Jessica Ruiz , Alves Daniele Cristina , Dias Lucas Souza , Viana João Henrique Moreira , Drumond João 
Published: November 2024

IntroductionThe aim of this study was to compare the effectiveness of brucellosis control and reproductive performance using one or two doses of RB51 strain vaccine.MethodsThis experiment was conducted at two commercial beef farms (A, n = 477; and B, n = 673), which were selected due to their records of endemic brucellosis and a prevalence of 6 to 8% of seropositive cows. An initial serology screening (Day 0) was carried out in all cows using the Rose Bengal test (RB), and presumptive positive results were re-evaluated using a slow agglutination test with 2-mercaptoethanol (2-ME). Seropositive cows (64, 5.6%) were culled. Non-reactive cows were then randomly assigned into three experimental groups: G1, a single vaccination with RB51; G2, two doses of RB51 given 6 months apart; and G3 (control group), no vaccination. Serological tests were carried out on Days 90, 180, 270, and 360. In each evaluation, seropositive cows were removed. The variables related to occurrence of new infections and abortion, as well as those related to subsequent reproductive performance, were analyzed using the SAS software.Results and discussionSeropositive cows were still detected in both vaccinated and control groups at 90 days. However, no new infections were detected in G1 at 180 days or in G1 and G2 at 270 and 360 days, whereas new seropositive cows were diagnosed in all exams in G3 (control). Therefore, the cumulative number of new infections was lower in vaccinated than in control cows (0.2% and 0.0%, vs. 3.2% for groups G1, G2, and G3 respectively; p = 0.0002). In farm A the number of days open was greater in the control than in vaccinated groups (p &lt; 0.05), and in farm B the pregnancy rate was lower in the control than in the group vaccinated once (p &lt; 0.05). In summary, vaccination with RB51 in beef cows reduces the occurrence of new cases of brucellosis and improves the reproductive performance. There is no indication that a second immunization, six months after the first, enhances protection or reproductive efficiency.
Continuous Glucose Monitoring for the Diagnosis of Post-Transplantation Diabetes Mellitus and Impaired Glucose Tolerance From Years One to Five After Kidney Transplantation—A Prospective Pilot Study
Authors: Eleftheriadis Georgios , Naik Marcel G. , Osmanodja Bilgin , Liefeldt Lutz , Halleck Fabian , Choi Mira , Schrezenmeier Eva , Zukunft Bianca , Tura Andrea , Budde Klemens 
Published: November 2024

Post-transplantation diabetes mellitus (PTDM) and prediabetes are associated with increased cardiovascular morbidity and mortality in kidney transplant recipients (KTR), when diagnosed by an oral glucose tolerance test (oGTT). Hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) display low concordance with the oGTT in the early phase posttransplant. For this prospective cross-sectional pilot study, 41 KTR from years one to five after transplantation without known preexisting PTDM (defined by HbA1c ≥ 6.5% (NGSP) or 48 mmol/mol (IFCC) at last visit or glucose-lowering therapy) were recruited at the Charité Transplant Outpatient Clinic. For each study participant HbA1c, FPG and an oGTT were followed by CGM. 38 of the 41 patients recruited had sufficient CGM-recordings (≥10 days). PTDM and impaired glucose tolerance (IGT), as defined by the gold standard oral glucose tolerance test (oGTT)-derived 2-h plasma glucose (2hPG), were diagnosed in one (3%) and twelve (32%) patients, respectively. HbA1c exhibited good test characteristics regarding IGT (ROC-AUC: 0.87); sensitivity/specificity of HbA1c-threshold 5.7% (NGSP) or 39 mmol/mol (IFCC) were 1.0/0.64, respectively. Best performing CGM-readouts mean sensor glucose and percent of time &gt;140 mg/dL (%TAR (140 mg/dL)) displayed acceptable diagnostic performance (ROC-AUC: 0.78 for both). Thus, HbA1c can aid in timely diagnosis of IGT in the stable phase after kidney transplantation.
Atendimento a paciente pediátrico com quadro agudo de meningite por tuberculose: um estudo de caso
Authors: Andrade Beatriz Bentes de , Gomes Caio Luiz Marques , Andrade Gabrielle Bentes de , Jardim Tyane de Almeida Pinto 
Published: November 2024

Introdução: A neurotuberculose é um tipo de tuberculose que invade o sistema nervoso central, considerada uma grave infecção causada pelo Mycobacterium tuberculosis. Objetivo: Realizar estudo de caso de um paciente pediátrico com quadro agudo de meningite por tuberculose. Metodologia: Estudo retrospectivo, descritivo, tipo relato de caso, construído a partir da análise do prontuário eletrônico do paciente. Estudo de caso: Paciente do gênero feminino, com idade de 4 anos e 11 meses, natural e procedente de Manaus, Amazonas, deu entrada em consultório de pronto socorro pediátrico em colo materno, mãe informou a ocorrência de dois episódios de queda de própria altura e hipotonia, seguidos de êmese com restos alimentares, sem outros sinais e sintomas associados. Foram realizados exame físico, exames laboratoriais e internação da paciente que permaneceu em monitorização contínua para investigação diagnóstica e tratamento do quadro. Conclusão: A tuberculose do sistema nervoso central (SNC), devido sua alta morbimortalidade, é uma das formas mais temidas na infância, sendo necessário manter vigilância e saber que o conhecimento e a compreensão dos protocolos e estratégias de atendimento em emergências pediátricas pode ser o diferencial em todas as circunstâncias adversas durante a assistência.
Intervenções fisioterapêuticas na redução da dor crônica após o cancêr de mama
Authors: Silva Antonia Heide de Souza , Viana Larissa Martins , Oliveira Gilberlandio Roseno , Cruz Junior Epaminondas Rodrigues da , Oliveira Stella Jorge de , Ramos Fabiana Castro , Passos Xisto Sena , Morais Fernanda Dorneles de 
Published: November 2024

Objetivo-. Identificar as melhores e mais utilizadas intervenções fisioterapêuticas para a redução da dor crônica em mulheres sobreviventes do câncer de mama. Métodos- Trata-se de uma revisão de literatura, segundo o método PRISMA. Para a busca da literatura, foram utilizadas as bases de dados BVS, SciELO e PubMed, resultando em 10 artigos originais publicados a partir de 2019, os quais apresentavam as intervenções fisioterapêuticas, para a redução da dor crônica após o câncer de mama, escritos em português e inglês. Resultados- Foram identificadas várias intervenções para a redução da dor crônica em mulheres câncer de mama nas quais, a maioria dos estudos obtiveram resultados satisfatórios e mostraram a eficácia de terapias como o TENS, TEAS, Cinesioterapia, Yoga, Radiofrequência, Drenagem Linfática Manual, Massagem, Corrente Interferencial e Acupuntura. Conclusão- As principais intervenções fisioterapêuticas para reduzir a dor crônica em pacientes oncológicos foram TENS, TEAS e Cinesioterapia, sendo que esta mostrando-se mais eficaz, apresentando desfechos favoráveis em todos os artigos analisados. Algumas terapias, como acupuntura e TEAS, não alcançaram os efeitos esperados, possivelmente devido à falta de estudos específicos.
ЭФФЕКТИВНОСТЬ РАЗЛИЧНЫХ ТЕХНОЛОГИЙ ХРАНЕНИЯ ПЛОДОВ ГОЛУБИКИ
Authors: В.А. Гудковский , Л.В. Кожина , Ю.Б. Назаров , А.В. Сутормина 
Published: November 2024

Технологии хранения в разной степени ингибируют созревание и развитие серой гнили плодов голубики, обеспечивают разные сроки эффективного хранения продукции. В условиях ОА они не превышают 10–14 суток, в условиях МА — 30 суток, в РА — 60 суток и более. Условия РА (t=0,5–1о С, СО2=10–12 %, О2=4–5 %) обеспечивают максимально высокий уровень сохранения качества (сохранение гармоничного вкуса продукции за счет сбалансированного содержания сухих растворимых веществ и титруемых кислот, сохранение структуры плодов, устойчивости к гнили).
Storage technologies differently inhibit the ripening and development of gray mold of blueberries and provide different periods of effective storage of production. Effective storage period does not exceed 10–14 days in RA conditions, 30 days — in MA conditions, 60 days or more — in CA conditions. Storage conditions of CA (t=0.5–1°С, CO2=10–12 %, O2=4–5 %) ensure the highest level of quality preservation (preservation of the harmonious taste of production due to the balanced content of dry soluble substances and titratable acids, preservation of the fruit structure, resistance to mold).
Analisis Perkembangan Kemampuan Sosial Emosional Anak Usia 4-6 Tahun di Tkn Nazaret Were
Authors: Meo Vinsensia , Marsianus Meka  , Efrida Ita  
Published: November 2024

This study aims to analyze the social emotional development activities of children aged 4-6 years at TKN Nazaret Were. This research was conducted at TKN Nazaret Were, Golewa District, Ngada Regency which was carried out within one month. The subjects in this study were 3 class teachers, 10 children and 10 parents of students. The results showed that the development of the child's social-emotional aspects did not develop according to the child's age level. This is caused by parenting patterns that are not in accordance with the needs of children, the level of health and nutrition of children who have not been fulfilled and learning methods that tend to be passive. Therefore a good understanding is needed in applying parenting patterns and applying learning methods. Various learning methods that can stimulate children's social emotional growth are exemplary, conversing, and telling stories. In applying the method, learning media should be used that support the method so that the goals of child development can be achieved optimally.

ABSTRAK
Penelitian ini bertujuan untuk menganalisis aktivitas perkembangan sosial emosional anak usia 4-6 tahun di TKN Nazaret Were. Penelitian ini dilakukan di TKN Nazaret Were Kecamatan Golewa Kabupaten Ngada yang dilaksanakan dalam waktu satu bulan. Adapun subyek dalam penelitian ini yaitu guru kelas sebanyak 3 orang, 10 orang anak serta 10 orangtua peserta didik. Hasil penelitian menunjukan bahwa perkembangan aspek sosial emosional anak tidak berkembang sesuai dengan tingkat usia anak. Hal ini disebapkan oleh pola pengasuhan yang tidak sesuai dengan kebutuhan anak, tingkat Kesehatan serta gizi anak yang belum tercukupi serta metode pembelajaran yang cendrung pasif. Oleh sebab itu diperlukan pemahaman yang baik dalam menerapkan pola pengasuhan serta penerapan metode pembelajaran. Berbagai metode pembelajaran yang dapat merangsang pertumbuhan social emosional anak yaitu keteladanan, bercakap-cakap, dan bercerita. Pada penerapan metode sebaiknya digunakan media pembelajaran yang menunjang metode tersebut sehingga tujuan perkembangan anak dapat dicapai secra optimal.
أنماط الجملة الإنشائيّة في الأمثال العربيّة
Authors: م.م. أفراح فرحان ماجد جابر  
Published: November 2024

تسعى الباحثة في هذه الدراسة إلى تسليط الضوء على البناء الإنشائيّ للجمل في الأمثال العربيّة، إذ تمثّل الأمثال إحدى المصادر اللغويّة التي لا تقل أهمية في بناء الثروة اللغويّة وصياغة النظام اللغويّ في جميع اللغات وليست العربيّة وحسب؛ فالمثل وليد بيئته الذي يعكس واقعها اللغويّ وغير اللغويّ، وقد تنوع البناء الصوريّ للجمل في الأمثال العربيّة في الجملة الإنشائيّة بين الإنشاء الطلبيّ وغير الطلبيّ، وذلك في مجموعة من الأنماط وقد كان لأنماط الإنشاء الطلبي حظوظ كبيرة في بناء الجملة الإنشائيّة للأمثال العربيّة.
الدراسات السابقة: الجملة الفعليّة ودلالتها في مجمع الأمثال للميدانيّ، ظواهر نحويّة في الأمثال العربيّة(دراسة في مجمع الأمثال للميدانيّ)، بناء الجملة في الأمثال العربيّة من خلال مجمع الأمثال للميداني، الأمثال العربيّة في معجم الطراز لابن معصوم المدنيّ(ت1120ه)- دراسة لُغوية.
Theoretical approaches of the quality of life and psychosocial adaptability
Authors: DRAGOMIR Diana-Elena 
Published: November 2024

The article features various theoretical approaches to the concepts of quality of life and psychosocial adaptability. Quality of life is a complex concept that has been studied from the perspective of several disciplines: psychology, philosophy, medicine, economics, environmental sciences, sociology. From a psychological standpoint, the analysis of the quality of life notion has led to the approximation of this concept to that of subjective well-being, as a result of including both life satisfaction and positive and negative emotions in their conceptual sphere. From the point of view of contemporary societal approaches, we consider the personality quality of life to be in direct relation to psychosocial adaptability. As a matter of fact, scientists believe that the degree of psychosocial adaptability is determined by the adaptive resources of the individual and by the characteristics of the concrete environment in the context of which the satisfaction of the basic needs of the individual takes place in a positive attitude.
Perilaku Kompulsif Remaja Pengguna NAPZA (Studi Kasus di Lembaga Rehabilitasi Narkoba Ghana Recovery)
Authors: Annisa Rachman  , Ishlakhatus Sa'idah  
Published: November 2024

Tujuan dari penelitian ini yaitu untuk memberikan gambaran perilaku kompulsif remaja pengguna NAPZA di lembaga rehabilitasi narkoba GhanaRecovery. Penelitian ini menggunakan metode penelitian studi kasus. Teknik pengumpulan data yang digunakan adalah wawancara, observasi, dan dokumentasi. Sedangkan Analisis datanya meliputi pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa perilaku kompulsif remaja pengguna NAPZA di lembaga rehabilitasi narkoba Ghana Recovery meliputi; (1) bentuk perilaku kompulsif pada remaja pengguna NAPZA yaitu, kehilangan kemampuan untuk mengontrol seberapa banyak menggunakan NAPZA, emosi yang tidak stabil, paranoid berlebihan, sulit berkonsentrasi, dan muncul kecemasan ketika tidak menggunakkan, (2) perilaku kompulsif muncul jika muncul keinginan kuat untuk menghindari stres atau tekanan, (3) cara remaja pengguna NAPZA mengatasi perilaku kompulsif yaitu pengalihan perhatian melalui kegiatan positif, tekad kuat untuk berhenti, dan menahan diri, serta mengurangi interaksi dengan teman yang juga pengguna NAPZA. Sedangkan cara lembaga rehabilitasi narkoba Ghana Recovery membantu mengatasi perilaku kompulsif pengguna yaitu detoksifikasi dan terapi kognitif, (4) sosok paling berpengaruh dalam membantu mengatasi perilaku kompulsif yang dialami remaja pengguna NAPZA adalah orang tua, konselor adiksi dan teman.
Orientation of Convex Sets
Authors: Ágoston Péter , Damásdi Gábor , Keszegh Balázs , Pálvölgyi Dömötör 
Published: November 2024

We introduce a novel definition of orientation on the triples of a family of pairwise intersecting planar convex sets and study its properties. In particular, we compare it to other systems of orientations on triples that satisfy a so-called interiority condition: $\circlearrowleft(ABD)=\circlearrowleft(BCD)=\circlearrowleft(CAD)=1$ imply $\circlearrowleft(ABC)=1$ for any $A, B, C, D$. We call such an orientation a P3O (partial 3-order), a natural generalization of a poset, that has several interesting special cases. For example, the order type of a planar point set (that can have collinear triples) is a P3O but not every P3O is the order type of some planar point set; a P3O that is realizable by points is called a p-P3O. If the family is non-degenerate with respect to the orientation, i.e., always $\circlearrowleft(ABC)\ne 0$, we obtain a T3O (total 3-order). Contrary to linear orders, a T3O can have a rich structure. A T3O realizable by points, a p-P3O, is the order type of a point set in general position. Despite these similarities to order types, P3O's and T3O's that can arise from the orientation of pairwise intersecting convex sets, denoted by C-P3O and C-T3O, turn out to be quite different from order types: there is no containment relation among the family of all C-P3O's and the family of all p-P3O's, or among the families of C-T3O's and p-T3O's.Finally, we study properties of these orientations if we also require that the family of the underlying convex sets satisfies the (4,3) property, as a first step towards obtaining better $(p,q)$-theorems.
How does it end? Endpoints of boundaries lead to completion in macro-events
Authors: Candan Şimşek Ayşe , Aydın Tolgahan , Huff Markus 
Published: November 2024

AbstractWhile watching someone kicking a ball, missing moments of ball contact can be incorrectly identified as seen if the event is continued in a causal manner (i.e., the ball flying off). Does event completion also occur for events of a larger scale such as having breakfast (macro-event), which consists of multiple sub-steps like toasting bread (micro-event)? We conducted two experiments to measure event completion in macro-events presenting portions of multiple micro-events. In Experiment 1, video summaries were formed with or without event boundary information where a macro-end was either present or absent. Macro-end signified an overarching goal achievement that signaled the completion of previous tasks (such as leaving the kitchen with a full breakfast plate). More completion occurred for summaries with event boundary information and macro-ends. In Experiment 2, we tested two alternative hypotheses to explore the underlying process by showing the beginnings or ends of a micro-event. While the predictive processing hypothesis suggests that event completion is based more on predicting the future states of the event based on beginning information, the backward inferences hypothesis suggests that event completion relies more on deductions formed after the fact based on event endings. Results of Experiment 2 suggest that the ends of event boundaries lead to more event completion, possibly due to their role in forming causal connectivity. These results help to further understand event completion on a macro level.
МЕТОДИЧЕСКИЙ ПРАКТИКУМ ПО ОБУЧЕНИЮ ЧТЕНИЮ: УТОЧНЯЮЩИЙ КОММЕНТАРИЙ К ТРАДИЦИОННОЙ СИСТЕМЕ ЗАДАНИЙ
Authors: М.Н. ЗОЛОТАРЕВА , Ю.М. НАУМЕНКО , О.А. ИЛЬИНА 
Published: November 2024

В статье уточняется вопрос подготовки системы заданий для работы с текстом на практических занятиях по РКИ. Уделяется внимание методическим комментариям к устоявшейся в практике системе заданий. Работа с текстом рассматривается как в контексте целого учебного процесса, так и относительно своих внутренних ча- стей. Представлена лингвометодическая разработка по чтению тек- ста о меценате П. М. Третьякове на занятии по РКИ (уровень А2+), иллюстрирующая реализацию уточняющих комментариев.
The article clarifies the issue of preparing some system of tasks for working with texts at practical lessons of Russian as a foreign language. The attention is paid to the methodological comments on the traditional system of tasks. The work with texts is considered both in the context of the entire educational process and in relation to its internal parts. The linguo-methodological material for reading a text about the philanthropist P. M. Tretyakov at the lesson of Russian as a foreign language (level A2+) is presented. And this illustrates the use of the given clarifying comments.
ОБУЧЕНИЕ СОЗДАНИЮ УЧЕБНЫХ ТЕКСТОВ ДЛЯ ИНОФОНОВ УРОВНЕЙ А1–А2 (ИЗ ОПЫТА РАБОТЫ СО СЛУШАТЕЛЯМИ ПО РКИ ПРОГРАММ ПРОФЕССИОНАЛЬНОЙ ПЕРЕПОДГОТОВКИ ПО РКИ)
Authors: О.Э. ЧУБАРОВА , Е.К. СТОЛЕТОВА 
Published: November 2024

В статье рассматриваются принципы создания учебного текста по РКИ, которыми руководствуются авторы в работе. Данные принципы были разработаны при анализе наиболее удачных об- разцов этого жанра, представленных в современных учебниках и учебных пособиях. Кроме того, даются рекомендации по при- менению рассматриваемых принципов при обучении будущих преподавателей РКИ. Приводятся примеры учебных текстов, созданных слушателями программ дополнительного образования и вошедших в текстотеку «Сайта энтузиастов РКИ».
This article discusses the principles of creating an educational text for foreign learners, which the authors use in their work. These principles were developed by analyzing the most successful examples of this genre – the authors’ educational texts presented in modern textbooks. In addition, recommendations are given on the application of these principles in the training of future teachers of Russian as a foreign language. Examples of educational texts created by students of additional education programmess and included in the text library of the Russian for foreigners Enthusiasts Website are given.