bluuebunny/crossref_metadata_2025_split huggingface dataset:
An equivalent parameter method based on acoustic performances for predicting sound target strength
Authors: Luo Y. Q. , Hou H. L. , Zhang Y. B. 
Published: November 2024

Sound target strength (TS) is one of the important indicators for measuring the acoustic stealth performance of underwater weapon platforms such as submarines and large unmanned underwater vehicles. The application of sound-absorbing structures is one of the key technologies for controlling the TS of underwater structures. The research on sound-absorbing metamaterials has emerged owing to the rapid development of acoustic metamaterials. Most sound absorption structures are implemented using local resonance models, which include thin-film metamaterials, curled space metamaterials, Helmholtz resonant cavities, local resonance scatterers, and so on. When these complex microstructures are applied to the surfaces of large underwater equipment, the finite element model for calculating TS has countless small mesh sizes due to the consideration of the fine features of the complex structures, resulting in a large number of meshes that are difficult to calculate or optimize. To solve this problem, the neural network deep learning model is utilized to extract the elastic equivalent parameters of complex sound-absorbing structures within a single period range based on the transfer matrix method of the elastic layer for the first time. This paper validates the typical homogeneous structures, composite sandwich structures, and composite structures with cavities. The errors in the TS values calculated from the original structures and the equivalent parameters are all within 2[Formula: see text]dB, taking the application of structures on a cylinder with a 0.5-m radius as an example. It demonstrates that these equivalent parameters can be used to accurately and quickly calculate the TS of complex sound-absorbing structures. The calculation method based on equivalent parameters proposed in this paper provides convenience and efficiency for the optimization design of structures pursuing lower sound target strength.
Longitudinal Associations Between Anxiety and Depressive Symptoms in Adolescence, Early Adulthood, and Old Age: Cross‐Lagged Panel Network Analyses
Authors: Wang Shoushi , Chong Zh Yeng , Zhang Chunyang , Xu Wei 
Published: November 2024

Background: Depression and anxiety are among the most prevalent psychiatric disorders worldwide, affecting individuals of all ages. The co‐occurrence of these disorders often exacerbates their negative health impacts, underscoring the necessity of understanding their comorbid mechanisms.Methods: This study employed cross‐lagged panel networks (CLPNs) to explore the longitudinal associations between depression and anxiety symptoms across three age groups and to compare the respective symptom networks. CLPNs were constructed through cross‐temporal associations between different symptoms, reflecting both the pattern of interaction and the significance of specific symptoms in comorbidity. The sample consisted of 1258 adolescents (aged 13–19 years, M = 15.98), 1118 college students (aged 17–24 years, M = 19.94), and 548 older adults (aged 60–101 years, M = 85.19) from China. Depression and anxiety symptoms were assessed using the subscales of the Depression, Anxiety, and Stress Scale Short Version (DASS‐21) at two time points over a 6‐month period during 2020–2021.Results: The findings revealed that the prevalence of depression and anxiety in adolescents, college students, and older adults was 25.9%/46.6%, 53.7%/61.5%, and 7.2%/22.5%, respectively. The network structure varied across age groups: adolescents and college students exhibiting a tight interconnection between depression and anxiety symptoms, while older adults showed stronger small‐world network characteristics. A key finding across all age groups was the central role of irrational fear. In addition, somatic anxiety symptoms frequently emerged as outcomes of other psychological symptoms.Conclusion: Depression and anxiety are more pronounced in college students compared to adolescents and older adults. Comparisons of the overall network structure provide insights into the lifelong trajectories of depression and anxiety symptom networks. The centrality of irrational fears and somatization symptoms is emphasized. These results offer guidance for more targeted clinical interventions.
Psychiatric Goals of Care at the End of Life: A Qualitative Analysis of Medical Records at a Geriatric Psychiatric Outpatient Clinic
Authors: Kullenberg Helena , Helgesson Gert , Juth Niklas , Lindblad Anna 
Published: November 2024

Objectives: Person‐centered care emphasizes patient choice and autonomy and is considered an important means for improving the quality of care and quality of life for older adults with multiple chronic conditions and functional limitations. In implementing person‐centered care, goals of care based on the patient’s preferences are considered fundamental. Psychiatry is generally practiced in a curative paradigm, and little is known about the goals of care in geriatric psychiatric settings. In this study, goals of care as documented in care plans and medical records in geriatric psychiatric outpatient care have been explored, with a special focus on the end of life.Methods: This study was based on a descriptive qualitative content analysis of medical records of patients enrolled at an outpatient clinic for geriatric psychiatry at the time of death. It was complemented by a basic quantitative analysis of patient characteristics.Results: A total of 66 medical records were included, with a male/female ratio of 41/59% and a mean age of 83 years (66–104 years). Among psychiatric diagnoses, depression predominated. The dataset was generally limited, and clearly defined goals of care were sparsely presented. Therefore, the included medical records were analyzed twice: first regarding goals of care and second regarding patient wishes and requests. In both cases, the highest level of abstraction in terms of themes was achieved. Analysis of goals of care resulted in the themes patient well‐being and care arrangements. Analysis of patient wishes resulted in the themes active patienthood and living and being.Conclusion: Goals of care were often disease‐oriented, focusing on recovery or symptom management, whereas analysis of patients’ wishes revealed personal goals other than remission, including outspoken existential needs. The results call for further research on the interplay between person‐centered care and the goal‐planning process and point to the potential of a palliative approach in geriatric psychiatric care involving patients with complex comorbidities and multilevel needs.
Pulsed Field Ablation of Paroxysmal Supraventricular Tachycardia: A Prospective Multicenter Single-Arm Study in China
Authors: Li Fanghui , Gong Aobo , Hu Hongde , Cui Kaijun , Yang Qing , Pu Xiaobo , Chen Shi , Jiang Jian , Fu Hua , Liu Hanxiong , Yin Yuehui , Zheng Qiangsun , Shu Maoqin , Gui Chun , Xu Jian , Yang Pingzhen , Ling Zhiyu , Wang Hongzhi , Yang Tingting , Yue Rongzheng , Gao Jinnian , Zhu Xiaolin , Shi Tiancai , Li Wentao , Hu Xianjin , Tong Yao , Zhang Qing , Zeng Rui 
Published: November 2024

BACKGROUND:
Pulsed field ablation (PFA) has gained attention in cardiac electrophysiology, but data on its application to paroxysmal supraventricular tachycardia are limited. This study aimed to assess the feasibility and safety of PFA and its combination with radiofrequency ablation for treating paroxysmal supraventricular tachycardia.

METHODS:
A prospective, multicenter, single-arm study was conducted across 8 centers in China. Patients with atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia, or Wolff-Parkinson-White syndrome underwent ablation using a focal point dual-mode PFA/radiofrequency ablation catheter. PFA was used to achieve acute ablation success, with consolidation using PFA for atrioventricular nodal reentrant tachycardia or near-His accessory pathways and radiofrequency ablation for far-His accessory pathways. Primary and secondary end points were acute ablation success and 180-day follow-up success, respectively.

RESULTS:
A total of 158 patients (77 with atrioventricular nodal reentrant tachycardia, 63 with atrioventricular reentrant tachycardia, 16 with Wolff-Parkinson-White, and 2 with both atrioventricular nodal reentrant tachycardia and atrioventricular reentrant tachycardia) completed the trial. Acute ablation was successful in 157 patients (99.37%). The skin-to-skin procedure time was 89.9±35.5 min. The median number of PFA discharges was 12 (8–19) with a median effective PFA discharge time of 4.6 (3.2–6.4) ms. Five patients (4 with atrioventricular reentrant tachycardia and 1 with Wolff-Parkinson-White syndrome) experienced paroxysmal supraventricular tachycardia recurrence during the 180-day follow-up period. One patient had a transient first-degree atrioventricular block resolving in 12 hours, and one patient had a transient third-degree atrioventricular block resolving in 24 hours. No permanent atrioventricular block or other adverse events occurred during the ablation procedure or 180-day follow-up period.

CONCLUSIONS:
PFA demonstrated the feasibility of the treatment of SVT. Reversible first- and third-degree atrioventricular blocks were observed following ablation in one patient each. The preliminary results indicated the safety and feasibility of a combination of PFA and radiofrequency ablation treatment for atrioventricular accessory pathways although it is impossible to determine the relative contribution of PFA.
Polygenic Prediction of Recurrent Events After Early-Onset Myocardial Infarction
Authors: Ardissino Maddalena , Paraboschi Elvezia Maria , Lambert Samuel A. , Kim Lois G. , Kelemen Martin , Maglietta Giuseppe , Crocamo Antonio , Magnani Giulia , Bricoli Serena , Vignali Luigi , Niccoli Giampaolo , Tubaro Marco , Pastika Libor , Sau Arunashis , Ng Fu Siong , de Marvao Antonio , Honigberg Michael C. , Natarajan Pradeep , Nelson Adam J. , Inouye Michael , Di Angelantonio Emanuele , Asselta Rosanna , Ardissino Diego , Butterworth Adam S. 
Published: November 2024

BACKGROUND:
Myocardial infarction (MI) is a complex disease caused by both lifestyle and genetic factors. This study aims to investigate the predictive value of genetic risk, in addition to traditional cardiovascular risk factors, for recurrent events following early-onset MI.

METHODS:
The Italian Genetic Study of Early-Onset Myocardial Infarction is a cohort study enrolling patients with MI before 45 years. Monogenic variants causing familial hypercholesterolemia were identified, and a coronary artery disease polygenic score (PGS) was calculated. Ten-fold cross-validated Cox proportional hazards models were fitted sequentially including all clinical variables, the PGS, and monogenic variants on the composite outcome of cardiovascular death, recurrent MI, stroke, or revascularization.

RESULTS:

During a 19.9-year follow-up, 847 (50.7%) patients experienced recurrent events. Each 1-SD higher PGS was associated with a 21% higher hazard of recurrent events (hazard ratio, 1.21 [95% CI, 1.13–1.31];
P
=4.04×10
−6
). Except for secondary prevention, PGS was the strongest determinant of recurrent event risk (C index, 0.56 [95% CI, 0.54–0.58]) compared with clinical risk factors. Overall, predictive performance of clinical risk factors (C index, 0.69 [95% CI, 0.67–0.71]) improved after adding the PGS (C index, 0.69 [95% CI, 0.68–0.71];
P
=0.006). When dividing the population by PGS quintiles, the highest fifth had a 57% higher hazard of recurrent events than the lowest fifth (hazard ratio, 1.57 [95% CI, 1.26–1.96];
P
=5.57×10
−5
).

CONCLUSIONS:
When compared with other clinical risk factors, PGS was the strongest predictor of event recurrence among patients with an early-onset MI. Though the discriminative power of recurrent event prediction in this cohort was modest, the addition of PGS significantly improved discrimination.
Hepatic Tissue Alterations in ST-Elevation Myocardial Infarction: Determinants and Prognostic Implications
Authors: Lechner Ivan , Reindl Martin , von der Emde Sebastian , Desheva Alina , Oberhollenzer Fritz , Tiller Christina , Holzknecht Magdalena , Kremser Thomas , Faccini Julian , Gollmann-Tepeköylü Can , Kremser Christian , Mayr Agnes , Bauer Axel , Metzler Bernhard , Reinstadler Sebastian J. 
Published: November 2024

BACKGROUND:
The presence and clinical significance of hepatic tissue alterations as assessed by cardiac magnetic resonance imaging in patients with ST-segment–elevation myocardial infarction (STEMI), are unclear. This study aimed to investigate associations of hepatic T1 patterns with myocardial tissue damage and clinical outcomes in patients suffering from STEMI.

METHODS:
We analyzed 485 patients with STEMI treated with percutaneous coronary intervention who were enrolled in the prospective MARINA STEMI study (Magnetic Resonance Imaging In Acute ST-Elevation Myocardial Infarction). Myocardial function and left and right ventricular (RV) infarct characteristics were assessed by cardiac magnetic resonance within the first week after STEMI. Native hepatic T1 times and extracellular volume were evaluated from standard cardiac T1 maps at baseline and 4 months thereafter.

RESULTS:

Median hepatic T1 times were 559 ms (interquartile range, 514–605) at baseline and decreased to 542 ms (interquartile range, 507–577) at 4 months (
P
<0.001). Hepatic T1 times at baseline were independently associated with female sex (β 0.116;
P
=0.008), hyperlipidemia (β −0.116;
P
=0.008), and myocardial tissue damage (infarct size: β 0.178;
P
<0.001; microvascular obstruction: β 0.193;
P
<0.001; RV infarction: β 0.161;
P
<0.001). Determinants of hepatic T1 times at 4 months were female sex (β 0.123;
P
=0.002), multivessel disease (β 0.121;
P
=0.002), N-terminal pro–B-type natriuretic peptide (β 0.101;
P
=0.010), RV infarction (β 0.501;
P
<0.001), and RV end-systolic volume index (β 0.087;
P
=0.031). Patients without a decrease exhibited a higher frequency of major adverse cardiovascular events (13% versus 5%;
P
=0.003). Hepatic T1 times at baseline (hazard ratio, 1.87 [95% CI, 1.40–2.50];
P
<0.001), 4 months (hazard ratio, 2.69 [95% CI, 2.15–3.36];
P
<0.001), and hepatic extracellular volume at 4 months (hazard ratio, 1.59 [95% CI, 1.33–1.90];
P
<0.001) were associated with major adverse cardiovascular events. After adjustment for univariable associates, only hepatic T1 times at 4 months were independently associated with adverse outcomes (hazard ratio, 2.86 [95% CI, 1.99–4.12];
P
<0.001).

CONCLUSIONS:
Hepatic tissue alterations determined by T1 mapping were associated with female sex, hyperlipidemia, multivessel disease, N-terminal pro–B-type natriuretic peptide, and left and RV myocardial tissue damage. These alterations can persist into the chronic phase after STEMI and indicate a worse clinical outcome.

REGISTRATION:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT04113356.
Cardiogenic Shock Complicating Takotsubo Syndrome: Sex‐Related Differences
Authors: Tomasino Marco , Núñez‐Gil Iván J. , Martínez‐Selles Manuel , Vedia Oscar , Corbí‐Pascual Miguel , Salamanca Jorge , Blanco‐Ponce Emilia , Cordón Clara Fernández , Almendro‐Delia Manuel , Pérez‐Castellanos Alberto , Martín‐García Agustín , Vila‐Sanjuán Sofía , Vazirani Ravi , Duran‐Cambra Albert , Becerra‐Muñoz Victor M. , Guillén‐Marzo Marta , Uribarri Aitor 
Published: November 2024

Background
Sex‐related differences in Takotsubo syndrome have been described, but no information is available in patients who develop cardiogenic shock.

Methods and Results

Of 412 patients with Takotsubo syndrome with cardiogenic shock, 71 (17.2%) were men. Male patients were older (71.1±12.2 versus 65.3±17.1 years,
P
<0.001), more frequently smokers (47 [66.2%] versus 66 [19.4%],
P
<0.01), with higher prevalence of neoplasms (6 [8.5%] versus 8 [2.3%],
P
=0.01), lower left ventricular ejection fraction (31% versus 37%,
P
<0.001), more frequent invasive mechanical ventilation (30 [42.3%] versus 90 [26.4%],
P
=<0.01), higher rate of infections (43 [60.6%] versus 148 [43.4%],
P
=<0.01), and longer in‐hospital stay (19±20 days versus 13±15 days,
P
=0.02). A total of 55 patients (13.3%) died during hospital admission, and 90 patients (21.8%) died at the end of the 5‐year follow‐up. Male sex was not significantly associated with the in‐hospital (odds ratio, 1.31 [95% CI, 0.64–2.68]) or 5‐year mortality rate (hazard ratio, 1.66 [95% CI, 0.93–2.94]). In the matched cohort, no significant differences in the short‐ and long‐term mortality rate were found either.

Conclusions
Cardiogenic shock due to Takotsubo syndrome has high short‐ and long‐term mortality rates that are similar in men and women.
An evaluation of a multidisciplinary care planning tool for people with intellectual disabilities and behaviours of concern
Authors: Tripp Tamsin , Goodey Rebecca , Deb Shoumitro , Thomson Oliver , Gartside Jonathan , Hipperson Kelvyn , Shankar Rohit 
Published: November 2024

Background Multidisciplinary care planning for people with intellectual disabilities who engage in behaviours of concern (BoC) is challenging and complex. Effective collaborative understanding and action planning across all stakeholders is essential. Cornwall’s Adult Community Learning Disability Team developed a care planning tool ( Connect Behaviour) using contemporary evidence and best practice. Connect Behaviour is designed to facilitate care planning by collaborative and enhanced shared understanding and is also available as an interactive web-based tool. Aim To evaluate Connect behaviour using stakeholders’ experiences. Methods Family members, care providers, advocates, social workers and professionals who had attended meetings guided by the Connect Behaviour care planning tool in a 3-month period were interviewed about their experiences of those meetings. This was interpreted using inductive thematic analysis. Results  Of 71 individuals identified as meeting this criterion of inclusion 61 were contactable and 27 consented to participation. These participants consisted of 17 health professionals, two parents, two social workers, three advocates, two positive behaviour support advisors within care providers, and one manager of a local care provider. The thematic analysis of participant views of connect behaviour generated five superordinate themes of ‘pragmatic’, ‘enabling’, ‘validation of effort’, ‘perceived lack of flexibility’ and ‘areas for development’. Further inquiry of themes highlighted subthemes of Connect Behaviour being ‘sensible’, ‘practical’, ‘collaborative’, ‘holistic’ and ‘action’. Conversely, some perceived a lack of flexibility in the care planning tool. Future areas for development were also identified in the data. Changes were recommended to increase the tool accessibility for people with intellectual disabilities, support stakeholders understanding of the tool, and consider utility for other clinical scenarios. Conclusions The evaluation established general feedback to continue to use the Connect Behaviour as a care planning tool. The benefits of Connect Behaviour in comparison to other care planning frameworks needs to be understood.
Achilles Tendon Ruptures in National Hockey League Players: Return to Sport and Performance Impact
Authors: Hayes Emmitt , Meulenkamp Bradley , Matache Bogdan , Pickell Michael 
Published: November 2024

Background: Few studies assess rates of return to play and postinjury performance in National Hockey League (NHL) players who sustain Achilles tendon ruptures. Our objective was to determine the rate of return to play and performance impact among NHL players who undergo surgical repair of Achilles tendon tears. Methods: NHL players who sustained an Achilles tendon rupture between 2001 and 2021 were identified using a publicly available injury database. Demographic and outcome data were collected for the 1-year period preceding and the 2-year period following surgery. Our primary outcome was expected wins above replacement per 60 minutes played. A position, draft year, and index season performance matched cohort was created. Pre- and postinjury outcomes were compared between cases and controls with a paired t test. Results: We identified 15 cases (9 forwards, 5 defencemen, 1 goaltender). Fourteen of 15 (93%) players returned to play. Preinjury, postinjury year 1, and postinjury year 2 expected wins above replacement were 0.05, 0.05, 0.05 respectively ( P > .05). There was no significant difference in performance between cases and controls at any time point. Conclusion: Achilles tendon tears are associated with a high rate of return to play in the NHL and are not associated with a significant change in offensive, defensive, or overall performance-based metrics. Level of Evidence: Level III, case-control study.
Endophytic bacterial community dynamics in sweet cherry in vitro shoot culture and their role in shoot adaptation after cryopreservation
Authors: Vinskienė Jurgita , Tamošiūnė Inga , Rugienius Rytis , Andriūnaitė Elena , Stanys Vidmantas , Baniulis Danas 
Published: November 2024

Abstract
Background
In vitro cultivation and cryopreservation techniques are essential tools for genetic diversity conservation and pathogen-free plant propagation of horticultural crops. The optimisation of cryopreservation protocols typically focuses on minimising the negative effects of pretreatment with cryoprotectors (CPs), cryogenic freezing (CF) treatment, and recovery procedures on explants. However, the impact of in vitro and CF techniques on plant-associated microbiota remains poorly understood, and their potential to improve plant adaptation after cryopreservation is underexplored. The aim of the present study was to investigate in vitro shoot culture and cryopreservation-induced changes in the endophytic bacterial diversity of two sweet cherry cultivars and to assess the potential of an inoculum of bacterial isolates to improve the growth of shoot culture after CF.

Results
Cultivars ‘Sunburst’ and ‘Mindaugė’ showed different responses to cold hardening preconditioning as well as different survival and regrowth rates after cryopreservation. Metataxonomic analysis revealed variation in the abundance and taxonomic composition of bacteria assigned to 35 families in samples of field-grown tree leaves, dormant buds, and in vitro shoot culture before and after CF treatment. Bacillaceae and Enterobacteriaceae bacteria were predominant in the leaf samples of both cultivars. For ‘Sunburst’, Pseudomonadaceae and Sphingomonadaceae bacteria were dominant in dormant buds and in vitro shoots, respectively, while Burkholderiaceae was largely predominant in the shoots following CF treatment. Conversely, ‘Mindaugė’ tissues exhibited more consistent colonisation by Bacillaceae and Enterobacteriaceae across the experimental groups, except for in vitro shoots where Mycobacteriaceae prevailed. A pure bacterial isolate inoculum was applied to the ‘Mindaugė’ shoot culture to counter the CF treatment-induced suppression of shoot growth (~ 40%). Cocultivation with Brevibacterium sp. S1-2, Bacillus cereus S1-3, or B. toyonensis Nt18 increased the shoot leaf area from 48 to 75%.

Conclusions
This study revealed that endophytic bacterial diversity is significantly reduced under in vitro conditions, often leading to a genotype-specific increase in the abundance and dominance of bacteria attributed to a single bacterial family. Moreover, shoot cocultivation with endophytic bacterial isolates has potential for improving the recovery of in vitro shoots after cryopreservation.