bluuebunny/crossref_metadata_2025_split huggingface dataset:
Targeted Topological Routine Regulation of RuNiOx Precursors for Excellent Alkaline Overall Water Splitting
Authors: Cai Ziyan , Yang Minghao , Xu Xiaoke , Bu Xiuming , Xiao Chuqian , Yang Yikai , Yin Di , Zhang Yuxuan , Gao Wei , Ho Johnny C. , Wang Xianying 
Published: November 2024

AbstractDesigning efficient and stable electrocatalysts for the hydrogen and oxygen evolution reactions (HER and OER) is crucial for green hydrogen production via the water‐splitting system. The bifunctional electrocatalyst offers a promising strategy due to the simplified preparation process and reduced expenses. However, the single‐component bifunctional catalysts often struggle to match the redox potential of water and to achieve proper adsorption/desorption of Gibbs free energy for both hydrogen and oxygen intermediates simultaneously. Herein, through precisely controlling the topological transformation path of the RuNiOx precursor, we successfully prepared high‐performance RuNi/Ni and Ru/NiO heterostructure electrocatalysts for the HER and OER, respectively. The energy level matching between the fabricated electrocatalyst and water oxidation/reduction potential confirms the feasibility of HER and OER. The synergistic effect between the active sites ensures rapid intermediate adsorption/desorption kinetics. As a result, the assembled alkaline overall water splitting setup achieves a current density of 1 A cm−2 at 2 V and maintains stable operation at 100 mA cm−2 for 100 hours.
Mass Spectrometry‐Based Platforms for Protein Lipoxidation Profiling
Authors: Tang Ziming , Wang Tianyang , Liu Chunrong 
Published: November 2024

AbstractLipid peroxidation, occurring through enzymatic or non‐enzymatic processes, generates lipid‐derived electrophiles (LDEs), which can covalently modify nucleophilic amino acid residues in proteins, a process known as protein lipoxidation. This modification can alter protein structure and function, either causing damage or regulating signalling pathways. Identifying the protein targets and specific lipoxidation sites provide important clues for unveiling the oxidative stress‐related protein interaction network and molecular mechanisms of related diseases. In this review, we present a detailed overview of recent advances in protein LDE modification profiling, with a focus on mass spectrometry (MS)‐based chemoproteomic platforms for global protein lipoxidation profiling.
Comprehensive Study on Amino‐Modified Salix Wood Powder Membranes: Preparation, Adsorption Mechanism and Desorption Conditions for Efficient Chlortetracycline Removal
Authors: Liu Xiaokai , Zhao Xuan , He Hao , Zhang Jiyuan , Zhang Yuanfang , Wang Li 
Published: November 2024

AbstractThe wastewater of Chlortetracycline (CTC) poses a threat to the balance of aquatic ecosystems, promoting the formation and dissemination of antibiotic‐resistant bacterial strains in the aquatic environment. Moreover, such pollution can directly or indirectly affect human health through water sources, exacerbating the issue of antibiotic resistance. In response to this pollution challenge, Amino‐modified salix wood powder membrane(ASPPM) was prepared by phase transition and wet spinning techniques, aimed at removing CTC from water bodies. Adsorption experiment results show that the ASPPM maximum adsorption capacity for CTC is 459 mg/g. In the desorption process, the highest desorption rate of ASPPM for CTC was 79.65 %. By fitting pseudo‐first‐order and pseudo‐second‐order kinetic models, it is found that the adsorption process of ASPPM on CTC is predominantly chemical adsorption. By fitting three isotherm models, it is found that the adsorption behavior of ASPPM on CTC is more in accordance with the Freundlich isotherm model, indicating multilayer adsorption on heterogeneous surfaces. Thermodynamic analysis indicates that the adsorption process of ASPPM on CTC is spontaneous, exothermic and accompanied by an increase in entropy at different temperatures. Furthermore, ASPPM has a highly porous structure. During its preparation, the characteristic absorption peaks of −CONH and −NH2 in ASPP are preserved and the cellulose type I in ASPPM is transformed into type II, resulting in a more orderly crystal structure. The preparation of ASPPM study not only transforms renewable biomass materials into effective tools for environmental purification but also offers a cost‐effective new approach for sustainable environmental management, expanding the application of biomass materials in the field of environmental protection.
Osimertinib Efficacy and Safety in Treating Epidermal Growth Factor Receptor Mutation‐Positive Advanced Non–Small‐Cell Lung Cancer: A Meta‐Analysis
Authors: Zhao Mengmeng , Zhang Jian , Gao Jie , Wang Jianping , Ma Zhenkai 
Published: November 2024

AbstractThis study compared the safety and efficacy of osimertinib, a third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), with those of other TKIs and its use alongside bevacizumab in patients with EGFR mutation‐positive advanced non–small‐cell lung cancer. PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, and VIP databases were used to conduct extensive searches for relevant randomized controlled trials until January 30, 2024. Osimertinib monotherapy favored disease control rate, whereas the comparator treatment arm favored overall survival. Using subgroup analysis, the objective response rate and progression‐free survival (PFS) were significantly elevated by Osimertinib monotherapy compared with pemetrexed combined with carboplatin or cisplatin. The comparator treatment arm receiving gefitinib or erlotinib significantly favored progression‐free survival and overall survival compared with osimertinib monotherapy. In patients treated with osimertinib monotherapy, the incidence of all adverse events (AEs) decreased compared with comparator treatment arm. Anemia was the only AE associated with osimertinib monotherapy. Pemetrexed combined with carboplatin or cisplatin resulted in greater loss of appetite than osimertinib monotherapy. The most associated AE of osimertinib monotherapy was diarrhea, according to network analysis. Although its efficacy is not consistent with other EGFR TKIs, osimertinib was associated with a decrease in AEs in patients with EGFR mutation‐positive advanced non–small‐cell lung cancer.
Crown Ether–Magnesium Ion Complexes: A Reliable Theoretical Estimation of Host–Guest Interaction and Binding Energies in a Solvent
Authors: Ćeranić Katarina , Milovanović Branislav , Petković Milena 
Published: November 2024

AbstractMetal ion detection is of paramount importance for health monitoring. The host should properly accommodate the desired ion and be selective with respect to other potential guests, which makes devising ion sensors a demanding task. Recently (Phys. Chem. Chem. Phys. 2023, 25, 32656), we suggested a procedure for a computational design of crown ethers that can capture magnesium ions. In the present contribution we apply the same approach to search for Mg2+ trap with thiophene units, in accord with proposed hosts for Na+ and K+ ions (Adv. Funct. Mater. 2016, 26, 514). Additionally, we present a procedure based on the combination of Density Functional Theory based Molecular Dynamics and the Interacting Quantum Fragments methodology for determination of host–guest interaction and binding energies in a model with a large number of explicit solvent molecules. The presented strategy could be applied for identification of the right host for an arbitrary guest.
ChemFET Anion Sensor Based on MOF Nanoparticles
Authors: Banning Douglas H. , Davenport Audrey M. , Lakanen Natalie M. , Huang Jiawei , Brozek Carl K. , Johnson Darren W. 
Published: November 2024

AbstractNanoparticles of metal‐organic frameworks (nanoMOFs) possess the unusual combination of both internal and external surfaces. While internal surfaces have been the focus of fundamental and applications‐based MOF studies, the chemistry of the external surfaces remains scarcely understood. Herein we report that specific ion interactions with nanoparticles of Cu(1,2,3‐triazolate)2 (Cu(TA)2) resemble the Hofmeister behavior of proteins and the supramolecular chemistry of synthetic macromolecules. Inspired by these anion‐selective interactions, we tested the performance of Cu(TA)2 nanoparticles as chemical field effect transistor (ChemFET) anion sensors. Rather than size‐based selectivity, the detection limits of the devices exhibit a Hofmeister trend, with the greatest sensitivity towards anions perchlorate, iodide, and nitrate. These results highlight the importance of the pore‐based supramolecular interactions, rather than localized donor‐acceptor pairs, in designing MOF‐based technologies.
Study on the Effect of Cations on Morphology in the Preparation of Vaterite Calcium Carbonate from Dolomite
Authors: Fan Tianbo , Zhang Xin'ai , Li Qiutong , Jiao Liqiang , Guo Hongfan , Li Xue 
Published: November 2024

AbstractIn this paper, the effect of trace components in dolomite on the morphology of vaterite calcium carbonate is studied in the CaCl2‐NH3‐CO2 system, with a focus on the effect of cations (Mg2+, Fe3+, Si4+, and Al3+) in the solution. Ca2+, NH4+, Mg2+, Fe3+, Si4+, and Al3+ in the digestion solution are proportionally prepared into a solution by analyzing the calcium rich digestion solution which is obtained by digesting dolomite with ammonium chloride solution. Under the optimal conditions, NH3 is introduced at a rate of 0.5 L min−1 for 1 h, CO2 is introduced at a rate of 0.5 L min−1 for 1 h and rotation speed of 500 r min−1 to prepare the vaterite calcium carbonate. The results show that the addition of Mg2+, Fe3+, Si4+, and Al3+ can promote the growth of vaterite calcium carbonate. Among them, adding Mg2+ and Si4+ can promote the dispersion of vaterite, Fe3+ and Al3+ can cause agglomeration of vaterite. Material Studio software is used to predict the crystal morphology of vaterite calcium carbonate under ideal conditions, and the calculation results are basically consistent with the experimental results.
Characterization of PbMo0.3W0.7O4 Crystal: A Potential Material for Photocatalysis and Optoelectronic Applications
Authors: Isik Mehmet , Gasanly Nizami Mamed 
Published: November 2024

AbstractPbMo0.3W0.7O4 semiconductor crystal, which contains the balanced ratios of Mo and W, is grown for the first time by Czochralski method. The structural and optical properties of the crystal are investigated in detail in the present study. Structural analysis shows that crystal has tetragonal structure like PbMoO4 and PbWO4 compounds. The optical characteristics are studied by transmission, Raman, FTIR and photoluminescence methods. The bandgap energy is found to be 3.18 eV, and the positions of the conduction and valence bands are determined. The vibrational characteristics are studied by means of Raman and FTIR spectroscopy techniques. Photoluminescence spectrum presents three peaks around 486, 529, and 544 nm which fall into the green emission spectral range. Taking into account the properties of the compound, it is stated that PbMo0.3W0.7O4 (or Pb(MoO4)0.3(WO4)0.7) has the potential to be used in water splitting applications and optoelectronic devices that emit green light.
Why Joint Development Agreement Is the Preferred Model for Settling the Kenya–Somalia Maritime Boundary Dispute
Authors: Kamwaria Alex Namu 
Published: November 2024

ABSTRACTThis policy brief delves into the procedures surrounding maritime zone disputes under UNCLOS and assesses their efficacy in settling prolonged maritime disputes that involve straddling natural resources and livelihoods in the context of Kenya–Somalia. Given the rise in maritime border disputes across Africa, the brief further examines the use of joint development agreements (JDAs) as a temporary measure for resolving such disputes. It analyzes the challenges associated with using JDAs to address maritime boundary delimitations, their impact on peace and security, and their relationship with local contexts, particularly concerning straddling natural resources and livelihoods. Ultimately, the brief aims to offer practical recommendations for resolving prolonged maritime disputes between neighboring states in Africa, with an emphasis on Kenya and Somalia.
Tailoring Intrinsic Oxygen Vacancies in P3‐Type Na0.66Mn0.66Mg0.33O1.93 to Enhance Oxygen Redox Activity
Authors: Wang Qin‐Chao , Zhang Jingkun , Zeng Zhiyong , Peng Zhaoquan , Zang Huilin , Li Xiaoge , Wang Chao , Han Jie 
Published: November 2024

AbstractIntegrating oxygen redox reactions with transition metal redox reactions offers a promising strategy to double or triple the energy density for large‐capacity battery cathodes. In this study, we have introduced intrinsic oxygen vacancies (VO) into a P3 layered cathode to modulate the electronic structure of O atoms and enhance oxygen redox activity. Rietveld‐refined X‐ray diffraction (XRD), X‐ray absorption spectroscopy (XAS), and X‐ray photoelectron spectroscopy confirm the successful creation of VO in Na0.66Mn0.66Mg0.33O1.93 (OV‐NMM). Density functional theory (DFT) calculations reveal that VO in OV‐NMM positively enhances the antibonding interaction between Mn and O, directing excess electrons from O holes toward adjacent Mn t2g and O 2p orbitals. This modification significantly improves the reversibility and accelerates Na+ transport kinetics for O2−/O− redox reactions. Ex situ synchrotron‐based XRD demonstrates that VO effectively eliminates the O3 phase, reduces Mg2+ migration, and suppresses irreversible structural changes. XAS of Mn K‐edge and O K‐edge further illustrate the advantageous role of oxygen vacancies in facilitating oxygen redox reactions. These findings highlight the potential of defect engineering, particularly VO, to boost anionic redox activity for high‐capacity energy storage applications.
Who Speaks Tho Fan? Deconstructing the Constructed Language of Jade Empire
Authors: Serada Alesha 
Published: November 2024

AbstractDespite being the largest East Asian country, China is underrepresented in video games, particularly those produced in the West. This article examines the video game Jade Empire (2005), developed by the acclaimed Canadian studio Bioware. Despite its age and now historical status in video game culture, Jade Empire remains one of the few relatively successful standalone video games based on Chinese culture (or appropriation thereof) created in the West. In addition to the borrowed elements of Chinese culture, the game uniquely introduces its own constructed language, Tho Fan, for world‐building. This article contextualizes this constructed language within the broader scope of constructed languages in Western fantasy and video games in particular, analyzing its creative and communicative potential. My analysis suggests that Tho Fan acts more as a tool of exclusion than of immersion, aligning with postcolonial critiques of video games. Conversely, Tho Fan has subversive potential when viewed as a metaphor for the inability of “the Subaltern” to “speak.” This ultimately presents a paradoxical issue of perceived authenticity in fantasy worlds that inherently defy historical accuracy.
Heidi A. Campbell. 2020. Digital Creatives and the Rethinking of Religious Authority. Routledge
Authors: Lipková Helena 
Published: November 2024

AbstractThe book Digital Creatives and the Rethinking of Religious Authority makes a valuable contribution to the study of how religious authority is evolving in the digital age. The author synthesizes previous research and introduces a new framework for categorizing types of religious authority in digital spaces. Building upon Anderson's earlier typology, Campbell significantly advances this framework through her original empirical research, which is based on a series of qualitative interviews with Christian religious digital creatives (RDCs). Campbell identifies nine distinct manifestations of RDCs, demonstrating how each type, through their actions, enacts media‐making narratives and engages in technological apologetics. Her approach offers a systematic and more nuanced classification and conceptual understanding of diversifying religious authority, reflecting the current plastic religious landscape and setting her work apart from previous studies. The book serves as a useful resource for scholars, offering insights and inspiration for further studies on the transformation of religious authority in new, hybrid spaces.
The Role of Fatty Acid Metabolism, the Related Potential Biomarkers, and Targeted Therapeutic Strategies in Gastrointestinal Cancers
Authors: Xie Ruixi , Luo Ying , Bao Bowen , Wu Xinshu , Guo Jia , Wang Jin , Qu Xiujuan , Che Xiaofang , Zheng Chunlei 
Published: November 2024

ABSTRACTGastrointestinal cancer has emerged as a significant global health concern due to its high incidence and mortality, limited effectiveness of early detection, suboptimal treatment outcomes, and poor prognosis. Metabolic reprogramming is a prominent feature of cancer, and fatty acid metabolism assumes a pivotal role in bridging glucose metabolism and lipid metabolism. Fatty acids play important roles in cellular structural composition, energy supply, signal transduction, and other lipid‐related processes. Changes in the levels of fatty acid metabolite may indicate the malignant transformation of gastrointestinal cells, which have an impact on the prognosis of patients and can be used as a marker to monitor the efficacy of anticancer therapy. Therefore, targeting key enzymes involved in fatty acid metabolism, either as monotherapy or in combination with other agents, is a promising strategy for anticancer treatment. This article reviews the potential mechanisms of fatty acid metabolism disorders in the occurrence and development of gastrointestinal tumors, and summarizes the related potential biomarkers and anticancer strategies.
GLP‐1: A Prospective Guardian for Comprehensive Myocardial Perfusion
Authors: Li Zhi , Yu Yao , Li Jie , Jiang Xiaoqiong , Chen Jie , Ye Ning , Wu Boquan , Sun Yingxian , Sun Guozhe 
Published: November 2024

ABSTRACTObjectiveTo investigate the role of glucagon‐like peptide 1 (GLP‐1) in myocardial perfusion, focusing on its effects on coronary microcirculation and cardiovascular outcomes.MethodsReview of foundational research and large‐scale clinical trials, including Cardiovascular Outcome Trials (CVOTs), examining the cardiovascular effects of GLP‐1. Systematic analysis of trial data to assess the impact of GLP‐1 therapy on myocardial infarction, composite cardiovascular events, and stroke incidence.ResultsGLP‐1 therapy was found to significantly reduce myocardial infarction and composite cardiovascular events. Additionally, GLP‐1 receptor agonists were observed to reduce stroke incidence, suggesting systemic effects on panvascular diseases. While direct protective effects on coronary microvasculature have been less studied, growing evidence supports GLP‐1's role in comprehensive myocardial perfusion.ConclusionGLP‐1 is a promising therapeutic agent for improving myocardial perfusion and reducing cardiovascular events. Its protection is likely associated with comprehensive improvements in myocardial perfusion, including effects on coronary microcirculation. Further research is needed to fully elucidate its mechanisms of action and potential clinical applications.
DNA Barcoding for the Identification of Adult Mosquitoes (Diptera: Culicidae) in Western Australia
Authors: Lamichhane Binit , Brockway Craig , Evasco Kimberly , Nicholson Jay , Neville Peter J. , Mackenzie John S. , Smith David , Imrie Allison 
Published: November 2024

ABSTRACTPrecise mosquito identification is integral to effective arbovirus surveillance. Nonetheless, the conventional morphological approach to identifying mosquito species is laborious, demands expertise and presents challenges when specimens are damaged. DNA barcoding offers a promising alternative, surmounting challenges inherent in morphological identification. To integrate DNA barcoding into arbovirus surveillance effectively, a robust dataset of mosquito barcode sequences is required. This study established a comprehensive repository of Cytochrome Oxidase I (COI) barcodes, encompassing 177 samples representing 45 mosquito species from southern and northern Western Australia (WA), including 16 species which have not been previously barcoded. The average intraspecific and interspecific genetic distances were 1% and 6.8%, respectively. Anopheles annulipes sensu lato had the highest intraspecific distance at 9.1%, signifying a genetically diverse species. While validating the potential of COI barcodes to accurately differentiate mosquito species, we identified that some species pairs have low COI divergence. This includes Aedes clelandi and Ae. hesperonotius, Tripteroides atripes and Tp. punctolaeralis and Ae. turneri and Ae. stricklandi. In addition, we observed ambiguity in identification of the members of Culex sitiens subgroup (Cx. annulirostris, Cx. palpalis and Cx. sitiens) and three members of Cx. pipiens complex (Cx. australicus, Cx. globocoxitus, Cx. quinquefasciatus). In summary, despite presenting challenges in the identification of some mosquito species, the COI barcode accurately identified most of the species and generated a valuable resource that will support the WA arbovirus surveillance program and enhance public health intervention strategies for mosquito‐borne disease control.
Competition, Drought, Season Length? Disentangling Key Factors for Local Adaptation in Two Mediterranean Annuals across Combined Macroclimatic and Microclimatic Aridity Gradients
Authors: Gade Florian , Metz Johannes 
Published: November 2024

ABSTRACTCompetition in mesic sites and drought stress combined with short growing seasons in drier sites are key environmental factors along macroclimatic aridity gradients. They impose a triangular trade‐off for local adaptation. However, as experiments have rarely disentangled their effects on plant fitness, uncertainty remained whether mesic populations are indeed better competitors and drier populations better adapted to drought stress and short season length. Aridity differs also at microclimatic scale between north (more mesic) and south (more arid) exposed hill‐slopes. Little is known whether local adaptation occurs among exposures and whether south exposures harbor conspecifics better adapted to drier climates that could provide adaptive reservoirs under climate change. We sampled two Mediterranean annuals (Brachypodium hybridum, Hedypnois rhagadioloides) in 15 sites along a macroclimatic aridity gradient (89–926 mm rainfall) on corresponding north and south exposures. In a large greenhouse experiment, we measured their fitness under drought stress, competition, and short vs. long growing seasons. Along the macroclimatic gradient, mesic populations were better competitors under benign conditions. Drier populations performed no better under drought stress per se but coped better with the short growing seasons typical for drier macroclimates. At microclimatic scale, north exposure plants were slightly better competitors in H. rhagadioloides; in B. hybridum, south exposure plants coped better with drought under short season length. We demonstrate that local adaptation to drier macroclimates is trading‐off with competitive ability under benign conditions and vice‐versa. Drought escape via short life‐cycles was the primary adaptation to drier macroclimates, suggesting that intensified drought stress within the growing season under climate change challenges arid and mesic populations alike. Moreover, the drier microclimates at south exposures exhibited some potential as nearby reservoirs of drier‐adapted genotypes. This potential needs further investigation, yet may assist populations to persist under climate change and lessen the need for long‐distance migration.