bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward a paradigm shift from deficit-based to proactive speech and language treatment: Randomized pilot trial of the Babble Boot Camp in infants with classic galactosemia
Authors: Peter Beate , Potter Nancy , Davis Jennifer , Donenfeld-Peled Inbal , Finestack Lizbeth , Stoel-Gammon Carol , Lien Kari , Bruce Laurel , Vose Caitlin , Eng Linda , Yokoyama Hanako , Olds Daniel , VanDam Mark 
Published: September 2019

Background: Speech or language therapy is typically initiated reactively after a child starts showing delays. Infants with classic galactosemia (CG), an inborn error of metabolism with a known high risk for both speech and language disorders, hold the keys towards evaluating whether preventive treatment is effective when the risks are known at birth. We present pilot data from a randomized parallel trial of an innovative proactive speech and language intervention program, the Babble Boot Camp (BBC). Method: Five children with CG, otherwise healthy, participated in the BBC from approximately 2 to 24 months of age. One of these was randomly selected as control receiving conventional management. A pediatric speech-language pathologist met weekly via telepractice with the parents in the treatment cohort. Parents implemented the prespeech, speech, and language stimulation and expansion activities according to the protocol. The control child was still too young for conventional treatment. Primary outcome measures were speech sound production complexity in babble and speech and expressive vocabulary size. Secondary outcome measures were developmental milestones in communication, motor, and cognition. Outcomes in the treatment cohort were compared to typical children and the control child and to typically developing children represented in test norms and cases described in the literature . The trial is ongoing. Results: All four treated children had higher speech sound skills in babble, three had higher speech sound skills in meaningful speech, two had higher expressive vocabularies, and three had higher communication and personal-social skills, compared to the control child with CG. Discussion: Given the high risk for speech and language delays in children with CG, finding on-schedule abilities in two or more of the treated children but not the untreated child is unexpected under random conditions. The trends toward beneficial effects of the BBC on speech sound production, expressive language, and communication milestones warrant appropriately powered larger clinical trials with full randomization. Trial registration: ClinicalTrials.gov NCT03838016 (12th February 2019).
TANTAS MÃOS: EDUCAR É MAIS QUE CONDUZIR, É DAR-SE AS MÃOS
Authors: Carvalho Carlos Roberto , Mello Marisol Barenco 
Published: September 2019

Esta entrevista é um texto dialógico, aonde os intelocutores conversam confrontando os pontos de vista e de cegueira, baseados em suas trajetórias de estudos e leituras de dois grandes pensadores do século XX: Hannah Arendt e Mikhail Bakhtin. Trata-se de uma conversa e os autores convidam os leitores a espiar dois velhos amigos falando de liberdade, de escritura, de literatura, de transformação, de linguagem e de educação. Um convite explicito ao pensar sem corrimãos a partir de suas vivências concretas no mundo.Palavras-chave: Hanna Arendt; Mikhail Bakhtin; linguagem e educacão.
A long-term follow-up of Sex Chromosomal Mosaicism Disorders of Sex Development
Authors: Listyasari Nurin Aisyiyah , Fitrianingrum Iit , Faradz Sultana MH 
Published: September 2019

Background:Chromosomal mosaicism is characterized by the presence of two or more distinct cell lines in an individual. Mosaicism in sex chromosome is a major component of Disorders of Sex Development (DSD) results in a large clinical spectrum of genital ambiguity. Case Presentation:We report long term follow-up of a 15-year-old male who was evaluated for ambiguous genitalia with a karyotype of 46,XY (85%) / 46,XX (15%). He presented with abnormal urethral opening (hypospadias) and left sided undescended testis since birth. Work-up was done for cytogenetic analysis, hormonal assays, imaging, exploratory laparotomy, and hypospadias repair. For more than 15 years he was reared as a boy, with no further complaints, until he reached puberty. He then developed gynecomastia and monthly painful hematuria. MRI evaluation revealed a left adnexal cystic mass and anteflexed uterus with loculated fluid collection posterior to urinary bladder suggesting hematometra. We discuss the genetics, diagnostics, as well as genetic counseling of this patient. Conclusion: This case is reported in view of the interesting clinical presentation of this rare mosaicism. A strong emphasis on a multidisciplinary approach and close follow-up is important to ensure both physical and psychological well-being of DSD patients.
Kooperatives Management geisteswissenschaftlicher Forschungsdaten
Authors: Müller Lars 
Published: September 2019

Zusammenfassung
Sobald in geisteswissenschaftlichen Forschungen Daten selbst erzeugt werden, wird Forschungsdatenmanagement erforderlich. Informationsinfrastruktureinrichtungen haben auf ein funktionierendes Datenmanagement mit der Digitalisierung von Kulturgut großen Einfluss, und nicht immer gibt es ein abgestimmtes Rollenverständnis. Die Verständigung über divergierende Sichten bei der Datenerzeugung durch die Domänen Forschung und Infrastruktur ermöglicht erfolgreiches Datenmanagement. Ein aktiver Datenmanagementplan dokumentiert diesen Prozess.
Schweizer Hochschulen vor den neuen Herausforderungen der digitalen wissenschaftlichen Information: das Projekt COSI (Coordination Office for Scientific Information)
Authors: Frey Jeannette , Esposito Piergiuseppe 
Published: September 2019

Zusammenfassung
„Coordination Office for Scientific Information“ (COSI) ist der Titel des Projekts zur Einrichtung einer Koordinationsstelle der Schweizer Hochschulen im Bereich der digitalen wissenschaftlichen Information. Durch die Analyse der Versionen des Detailkonzepts COSI erläutert der Artikel den Hintergrund des Projekts und die Ergebnisse der Implementierungsarbeit der COSI-Projektgruppe. Die verschiedenen Versionen des Detailkonzepts COSI zeigen, dass es sich noch um ein Work-in-progress handelt.
Mineralizing the Right to Prior Consultation: From Recognition to Disregard of Indigenous and Peasant Rights in Peru
Authors: Guevara Gil Armando , Cabanillas Linares Carla 
Published: September 2019

AbstractBy using a sociolegal analysis, this article shows how the Peruvian State has used administrative mechanisms to prevent the free, prior and informed consultation of indigenous and peasant communities impacted by mining projects throughout the country. Prior consultation – a fundamental right for these communities – is being drained of its content by ad hoc procedures of a mining bureaucracy bent on ignoring it. For this, the main strategy has been to deny the identity of indigenous peoples and, by doing so, divest them of their collective rights. The goal has been to promote the expansion of the mining industry at all costs. In the context of an extractivist economy, indigenous rights loose substance. The state has thus moved from the discursive recognition of indigenous rights to its effective disregard. However, the reaction of other state agencies against the systematic denial of indigenous collective rights offers not only hope but the chance to assess the tension between economic and special human rights.
Five Ways of Investigating Adnominals in Czech Sonnets of the 19th and 20th Centuries
Authors: Místecký Michal 
Published: September 2019

Abstract
The paper focuses on analysing the use of adnominals in the selected fifteen sonnet authors of the 19th- and 20th-century Czech literature. The poets have been selected so as to represent the main literary schools of the period, the main criterion of their ranking being their dates of birth. The investigation treats both general trends (changing numbers of adnominals in various eras, the measure of ornamentality in particular authors), and specific, Czech-based issues (premodification and postmodification, attributes and genitives). The goal of the paper is threefold: first, there is an endeavour to determine some principles of the development of the sonnet tradition in the Czech literature; second, some micro-analyses of the poets are provided, including contrastive views of various writing tactics employed by them; and third, one way of measuring ornamentality has been sketched, as the tool may be of help in unearthing stylistic preferences of different authors. All counts and figures are accompanied with interpretations which may be further enriched by literary scholars.
Catalytic Synthesis of Monoglycerides by Glycerolysis of Triglycerides
Authors: Alvarez Serafini Mariana Soledad , Tonetto Gabriela Marta 
Published: September 2019

Abstract
The synthesis of monoglycerides by the transesterification of triglycerides with glycerol was studied using zinc glycerolate as a heterogeneous catalyst.
The effect of the operating variables on the triglyceride conversion and monoglyceride yield was evaluated. The maximum values of triglyceride conversion and monoglyceride yield reached at 2-hour reaction time were 83 and 49 %, respectively. These values were obtained at 240 °C with 3 % catalyst loading and glycerol/oil molar ratio of 6. When the molar ratio of the reactants was increased, the triglyceride conversion and monoglyceride yield achieved an optimum value. This behavior was related with a competitive adsorption of the reagents.
It was possible to reuse the catalyst without significant changes in activity.
Thermal Energy Transport Across Combined Films: Thermal Characteristics
Authors: Ali Haider , Yilbas Bekir S. 
Published: September 2019

Abstract
Thermal energy transfer in combined thin films consisting of silicon and diamond is considered. The combined films are thermally disturbed by a temperature oscillation at the silicon left edge and the influence of pulse length of temperature oscillation on energy transport characteristics is investigated. A nano-size gap with varying length is adopted at the films interface. The Boltzmann equation is adopted for the predictions of phonon intensity in the combined structure. The cut-off mismatch model is accommodated formulating interface conditions. The contribution of the near field radiation, due to evanescent waves, is also included at the interface. Equivalent equilibrium temperature is used quantifying phonon intensity distribution in the combined structure. It is found that the influence of the temperature oscillation on the phonon transport is significant at the silicon interface, i. e., increasing pulse length reduces phonon intensity at the silicon interface. Temporal behavior of equivalent equilibrium temperature is similar to the temperature oscillation introduced at the left edge of the silicon. The rise in temperature in the combined film is faster in the beginning of the heating cycle.
Smart Self-Healing and Self-Sensing Cementitious Composites—Recent Developments, Challenges, and Prospects
Authors: Das Avik K. , Mishra Dhanada K. , Yu Jing , Leung Christopher K. Y. 
Published: September 2019

Abstract
The use of smart cementitious materials is becoming increasingly critical for the enhanced serviceability of structures. The addition of carbon fibers, carbon nanotubes, and various nano-powders such as nano-silica, carbon black, and graphite giving cementitious materials electrical properties that can be used for self-sensing has been known for almost two decades. Many sensing principles and techniques using smart materials have been successfully developed and applied mostly in laboratory testing over last few decades. The strong capacity of Fiber-Reinforced Cementitious Composites for autogenous healing in addition to crack control (especially in the case of Strain-Hardening Cementitious Composites) has been reported by many researchers. Similarly, the applications of different mineral and bio-additive materials to achieve the self-healing of cracks have been noted with great interest. Design for serviceability based on the durability of the materials used in concrete structures is often neglected. With durability performance testing becoming more sophisticated, detailed service life design is being demanded in the most important infrastructure projects. The present review is focused on identifying field applications and highlighting the Performance-Driven Design Approach for tailoring material solutions for the problems likely to be faced by civil infrastructures in the future. A real-life case study is presented to illustrate the minimal cost implications of adopting the latest smart material for an eco-friendly, durable, reliable, and resilient infrastructure. Identifying critical challenges faced by the industry and developing solutions for the same is going to help bridge the current gaps between research and adoption.
Immunity and Its Effect on the Incidence of Multiple Organ Failure in Patients after the Heart Surgery
Authors: Partylova E. A. , Petrishchev Yu. I. , Kudryavtsev I. V. , Malkova O. G. , Levit A. L. 
Published: September 2019

The purpose of the study is to identify the components of immunity, which might predict the development of multiple organ failure in patients after heart surgery.Material and methods. The study included 40 patients who were operated in cardiac surgery Department. The inclusion criteria were the presence of indications for cardiac surgery. The exclusion criteria were the presence of infective endocarditis in patients. Before the operation and after 24 hours we studied the blood level of leukocytes and lymphocytes. We analyzed the phenotype of immune cells using monoclonal antibodies, serum levels of procalcitonin and C3 and C4 complement components. All patients were evaluated for multiple organ disfunction (MOD) using the SOFA scale.The results showed that cardiac surgery leads to the development of MOD, statistically significant multidirectional changes in both quantitative and qualitative composition of all cells of the immune system, significant changes in the level of C3 and C4 components of the cascade of complement and plasma level of pro-calcitonin. ROC analysis was revealed that the relative content of monocytes is less than 7.1% of the number of leukocytes as well as the absolute content of monocytes with the CD14 + HLA-DR + phenotype less than 0.32_109/l in the preoperative period, and the C3 level of the complement component less than 0.52 g/l, as well as the maximum SOFA score in the postoperative period, were the best predictors of MOD after the procedures.Conclusion. The components of innate immunity make it possible to predict the complication of the cardiac surgery, earlier than the SOFA scale.
Neurotropic Effects of Hepatoprotectors During Alcohol Poisoning
Authors: Akalaev R. N. , Sharipova V. Kh. , Stopnitsky A. A. , Khodzhiev K. Sh. 
Published: September 2019

Purpose.To compare the efficacy of metabolic hepatoprotectors at an early stage of acute alcohol poisoning complicated by toxic hepatitis.Material and methods.80 patients with acute alcohol poisoning complicated by toxic hepatitis who received medical treatment in the toxicology unit of the Republican Research Center of Emergency Medicine during 2015–2017 were examined. The patients were split into 3 groups. At the background of backbone therapy, patients of group I (n=30) received a hepatoprotectors on the basis of inosine, meglumine, methionine, nicotinamide, and succinic acid; patients of group II (n=20) were prescribed to receive drugs based on betaine glucuronate (glucomethamine), diethanol amine (glucodiamine), and nicotinamide ascorbate. Patients of group III (n=30) received the backbone therapy. In all patients, the concentrations of liver enzymes, bilirubin, free ammonia, blood lactate, the condition of vegetative nervous status were analyzed. Psychoastenics was examined using the MMSE score, FAB score and Reitan test.Results.After 48 hours, in group I patients, the concentration of blood lactate became almost normal, in group II patients it decreased to 2.6Ѓ}0.9 mmol/l, and in group III patients it was equal to 2.7Ѓ}0.9 mmol/l. On day 5, in patients of groups I and II the cognitive deficit was almost absent, in patients of group III the MMSE scores were 1.3-fold and 1.4-fold lower than in patients of groups I and II, respectively.Conclusion.The drug used in group I possessed increased antihypoxant properties but smaller hepatoprotective properties than the drug used in group II. When signs of toxic hepatitis are predominant it would be more preferable to use the drug applied in group II and when the signs of tissue hypoxia are predominant the drug applied in group I should be used.
Early Ultrasound Signs of Splenomegaly in Neonates
Authors: Perepelitsa S. A. , Alekseeva S. V. , Vozgoment О. V. 
Published: September 2019

The purpose of the study is to determine early non-invasive (ultrasound) diagnostic criteria of splenomegaly in neonates with a high risk of congenital or postnatal infection.Materials and methods. In the prospective study, 163 newborn infants of the first week of live were included. All neonates included in the study were classified as possessing a high risk of an intra-uterine infection (IUI). Depending on the birth weight, the infants were split into two groups: group «А» — 80 full-term newborns with normal birth weight, and group «В» — 83 full-term newborns with fetal growth restriction (FGR). A comprehensive examination of newborns including spleen ultrasound was carried out.Results. An increased spleen weight coefficient (Km) was found in newborns with high risk of infection development that included congenital oromaxillofacial and gastrointestinal defects, perinatal contacts with various microorganism. The increased spleen weight and Km reflected conditions of the immune system organ of the newborn in response to an adverse exposure including infection.Conclusion. Ultrasound examination of morphometrical characteristics of the spleen in newborns with various medical conditions represents a convenient and simple method of early diagnosis of splenomegaly. The most sensitive index is the spleen weight coefficient (Km), which reflects the immune system organ response to an adverse perinatal exposure including contact with an infectious agent. The mean spleen weight coefficient is within the range of 1.1 to 3.0. When the index exceeds 4, the risk of development of an infectious disease increases. This method can be used as a screening approach for newborns of different gestation age who have been included in the high-risk group based on a congenital or early postnatal infection.
The Cosa Mithraeum: A Long Overdue Survey
Authors: Henriques James C. 
Published: September 2019

Summary
Very likely due to its modest nature, the Cosa Mithraeum has been mentioned in scholarly publications only four times – each in passing – since its discovery in 1954. This sparse attention, restricted solely to literature on Cosa, has meant that the mithraeum is well-known among those intimately familiar with the colony, but has languished in complete obscurity among Mithraic scholars for the past half century. In addition to bringing the Cosa Mithraeum to the attention of a wider audience, this article also argues for a re-evaluation of the most recent dating of the mithraeum. Recent advances in scholarship on mithraea at Ostia give ample reason to suggest that the original date for the Cosa Mithraeum might be more accurate than later interpreters have assumed. Furthermore, the ongoing excavations of Cosa's bath complex, conducted by Florida State University, Bryn Mawr College, and Tübingen University have revealed a city that was still quite active during the 2nd century CE. In light of these developments, this article is an overdue study of the Cosa Mithraeum and its role in the history of the colony.
Mithras in Moesia Inferior
Authors: Bottez Valentin 
Published: September 2019

Summary
The paper starts by adding to the corpus of Mithraic monuments the recently (re)discovered monuments, from Carsium, Nicopolis ad Istrum, Tropaeum Traiani, Tomis and Capidava. In the second part it focuses on the differences and similitudes between the cults in Novae and Istros, by analysing Mithraism's place in their respective communities.
The Discovery of the Mithras Statue of Tarquinia
Authors: Scapaticci Maria Gabriella 
Published: September 2019

Summary
In 2014 the discovery of a Mithras' statue at Tarquinia occurred. This was due to the Comando Tutela Patrimonio Culturale dell'Arma dei Carabinieri, which informed the Soprintendenza per i Beni Archeologici dell'Etruria Meridionale about clandestine activities in May 2014 on the poggio della Civita – where the ancient city of Tarquinia stood – in a zone close to the Etruscan temple of the Ara della Regina (fig. 1).
As soon as possible, the Soprintendenza carried out an archaeological excavation, focusing the effort on the need to find evidence for the place of origin of the magnificent sculptural group (fig. 2), which represents Mithras Tauroctonus. This sculpture was recovered by the Carabinieri after investigation by the police, directed by the Procura della Repubblica of the law court of Rome.
Archaeological research since then has led to the discovery of another marble part of the same sculpture (fig. 3), i.e., the dog leaning on the knee of the bull and perfectly dovetailing with the Mithraic Tauroctony. The discovery of another fragment pertaining to the same sculpture is an irrefutable proof that the Mithras' statue came from the domus of the Civita of Tarquinia, which represents an important and new scientific result.
The only other sculptural group depicting Mithras in Southern Etruria was one previously found in Vulci, discovered in 1975 after a clandestine excavation close to the domus del Criptoportico. This new finding proves the spread of this cult in Tarquinia, as well, and the style of the new sculpture suggests a chronological priority of the Tarquinian Mithraeum in respect to that in Vulci.
The Material Evidence of the Roman Cult of Mithras in Dacia
Authors: Szabó Csaba 
Published: September 2019

Summary
Since M. J. Vermaseren's visit to Romania and the publication of the second volume of his monumental corpus on Mithraic finds in 1960, the once-called “Mithraic Studies” has had numerous paradigmatic shifts and changed its major focus points. Besides the important changes in the theoretical background of the research, the archaeological material regarding the Mithraic finds of Dacia – one of the richest provinces in this kind of material – has also been enriched. Several new corpora focusing on the Mithraic finds of Dacia were published in the last decade. This article will present the latest currents in the study of the Roman cult of Mithras and will give an updated list of finds and several clarifications to the latest catalogue of Mithraic finds from the province.
Epigraphic Records of the Friendship of Mithras and Sol in Pannonia
Authors: Vágási Tünde 
Published: September 2019

Summary
Regarding the Mithras cult, Pannonia had an exceptional status in the Roman Empire. This unique status was connected with the huge numbers of military forces stationed there. Numerous inscriptions and altars give evidence that Pannonia had an uncommon sensitivity for religions; this is why some local characteristics and relief-versions could be made, for example: dadophores with pelta shields, and unique dedicational forms which are mostly known in Pannonia, and perhaps spread from there to other parts of the Empire. In my paper, I want to show the connections between Mithras and Sol on their Pannonian representations.