bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design, synthesis and evaluation of anti-inflammatory, analgesic and antibacterial activity of 2, 4, 6-trisubstituted quinazoline derivatives
Authors: Jain Nivrati , Jain Harshita , Jain Ashish , Ravichandran Veerasamy , Jain Prateek 
Published: October 2018

Abstract
We described here the synthesis and biological evaluation of a series of 2, 4, 6-trisubstituted quinazoline derivatives as potential anti-inflammatory, analgesic and antibacterial agents. The synthesized compounds were characterized by FTIR, 1H NMR and mass spectroscopy analysis. We found that the compounds 6b, 6e, 6g, 6h and 6j showed better anti-inflammatory activity than indomethacin. Compounds 6b, 6e, 6h, 6j and 6l were found to exhibit appreciable analgesic activity, and 6b, 6g and 6k showed good antibacterial activity against Gram (+) bacteria: B. subtilis, S. aureus, S. epidermis, and Gram (-) bacteria: E. coli, P. aeruginosa and K. pneumoniae. Compound 6b showed overall better anti-inflammatory, analgesic and antibacterial activity among the synthesized compounds. The results of the present study could be helpful for the designing of effective anti-inflammatory, analgesic and antibacterial agents.
What does the water inside the brain tell us? Diffusion tensor imaging
Authors: Acer Niyazi , Dundar Mehmet Sait , Bastepe-Gray Serap 
Published: October 2018

Abstract
The brain consist of about 75 percent water. Diffusion tensor imaging (DTI) is an advanced magnetic resonance (MR) technique imaging that has been developed for diagnostic and research in medicine. It can be use DTI tractography to better understand degenerating axons of white matter lesions in some neurological diseases such as MS, AD, trauma, cerebral ischemia, epilepsy, brain tumors and metabolic disorders.
Spatial Diversity of Municipal Capital Companies in Poland
Authors: Satoła Łukasz 
Published: October 2018

Abstract
Subject and purpose of work: This article aims to identify the spatial diversity of Polish municipal services companies operating pursuant to the Commercial Companies Code. Materials and methods: The data from the database Structural changes of national economy entities in the REGON register was used. To evaluate the spatial diversity in the occurrence of municipal services companies, this article employed an indicator of the number of municipal capital companies per commune. Results: Although there is a clear spatial diversity among municipal services companies, their number in Poland increased significantly during the period 2005-2015. The majority of these companies operate in the most industrialised and urbanised regions. Conclusions: The form of a capital company in the municipal economy sector is the most suitable for a large scale of conducted operations. A small scale of operations, characteristic mainly of rural communes, predisposes them for applying the form of a budgetary establishment.
Conceptualization of Geo-Economic Threats in Small Countries with Transition Economies
Authors: Kvinikadze Giorgi 
Published: October 2018

Abstract
Subject and purpose of work: The main goal of this work is to identify and systematize the geoeconomic threats that directly affect the development of small countries with economies in transition. The subject of the study is geoeconomic security (GES) of small countries with economies in transition. As an independent variable is GES, and the dependent GES of Georgia. Materials and methods: The research is of an empirical nature, and belongs to the category of qualitative research. The case-study method is used as a basic methodological approach. Results: The future of the country should be viewed in a geo-economic context.The country’s security should be developed through economic cooperation, which would not only ensure stability and economic growth would also benefit both in terms of political and in the economic security. Conclusions: Georgia needs to fully use its geo-economic potential (both internal and external), which is a reliable source of weakening geo-economic threats.
Aplikasi Penentuan Rute Distribusi LPG 3 Kg
Authors: Meilani Difana , Iswara Arefa 
Published: October 2018

PT IB. Sumberdaya Development is one of LPG agent partners of PT Pertamina. This company is assigned to distribute 3 kg LPG. The LPG shipment is carried out from Monday to Saturday. The shipment goes to 66 depots using agent vehicle which are registered in PT Pertamina. From the preliminary study, there were problems which related to the long-distance shipment, and the limitation of transportation and capacity. In this research, the shipment routes of 3 kg LPG in PT IB is determined. Sumberdaya Development problems consist of the distance of the travel, the time of travel, and optimal transportation cost. Based on Clarke and Wright Savings Matrix algorithm, by considering the vehicle capacity, the distance can be minimized. The point of this algorithm is calculating the saving by measuring the available reduction of distance and time. It is done by linking the existing depots and making a route which is based on the largest saving value of the distance from the agent to the destination depot. Each route is optimized by WIN QSB software by using Branch and Bound method. A program to facilitate the determination of shipment routes by using PHP programming language is designed. The proposed route for the 3kg LPG shipment is 762.35km with 33.58% saving, and the proposed time is 2929 minutes with 15.27% saving. The shipment schedule is designed from Monday to Saturday day to Saturday with each of 7 routes. This is better than the actual route used by the company.
Rendimiento y componentes de producción de híbridos de maíz en la Comarca Lagunera.
Authors: Borroel García Victoria Jared , Salas Pérez Lilia , Ramírez Aragón Mercedes Georgina , López Martínez José Dimas , Luna Anguiano Jesús 
Published: October 2018

El desabasto de maíz grano para consumo humano hace necesario mejorar su ef iciencia de producción haciendo una selección adecuada de híbridos con características adaptables a determinada región. El objetivo de esta investigación fue evaluar cinco híbridos de maíz sobre el rendimiento y componentes de producción en la Comarca Lagunera. Los híbridos evaluados fueron: SB302 (testigo), RX715, Caimán, Oso y Ocelote, los cuales fueron establecidos en campo bajo en un diseño de bloques completos al azar. Los híbridos Caimán, RX715, Oso y SB302 obtuvieron los mayores rendimientos de grano, 14.52 a 15.84 Mg ha‑1. Los componentes de producción presentaron una correlación positiva entre longitud y diámetro de mazorca (r = 0.74), longitud de mazorca y granos por hilera (r = 0.83), longitud de mazorca y granos totales por mazorca (r = 0.81). Asimismo, diámetro de mazorca con granos por hilera (r = 0.62), número de hileras con granos totales por mazorca (r = 0.51) y granos por hilera con granos totales por mazorca (r = 0.86). El rendimiento presentó correlación positiva con diámetro (r = 0.90) y longitud de mazorca (r = 0.77). Se concluye que el híbrido Caimán obtuvo un rendimiento superior (15.84 Mg ha‑1) a la media nacional en maíz grano, por tanto se hace la recomendación de potencializar la siembra de maíz grano en la región de la Comarca Lagunera.
Efecto del cambio de uso de suelo en las propiedades químicas de un vertisol.
Authors: Yáñez Díaz María Inés , Cantú Silva Israel , González Rodríguez Humberto 
Published: October 2018

Las propiedades químicas son indicadoras de la calidad del suelo, las reservas nutritivas pueden modif icarse debido a las actividades antropogénicas. Para evaluar el efecto sobre las propiedades químicas de un suelo de tipo vertisol, se analizaron los nutrientes bajo cuatro sistemas de uso de suelo: matorral espinoso tamaulipeco, pastizal, cultivo agrícola y una plantación de eucaliptos, ubicados en el noreste del estado de Nuevo León, México. Se colectaron cuatro muestras de suelo compuestas por sitio a dos profundidades (0-5 cm y 5-30 cm) analizándose pH, conductividad eléctrica (CE), capacidad de intercambio catiónico (CIC), macronutrientes (K, Ca, Mg y Na) y micronutrientes (Cu, Mn, Fe y Zn). De acuerdo a los resultados obtenidos, se encontraron diferencias signif icativas (P ≤ 0.05) entre los sistemas de uso para pH, Mg (cmol(+) kg-1), Fe (mg L-1) y Cu (mg L‑1) en las dos profundidades. La CE (dS m-1), Zn (mg L-1) y CIC (cmol(+) kg-1), presentaron diferencias en la profundidad 0-5 cm, mientras que Ca (cmol(+) kg‑1), Na (cmol(+) kg-1) y Mn (mg L-1) para la profundidad 5-30 cm. Los nutrientes P (mg kg‑1) y K (cmol(+) kg‑1) no presentaron diferencias entre los sistemas en las dos profundidades. Se realizó una correlación de Spearman entre las variables, siendo el pH la variable que presentó una relación con la mayoría de los nutrientes, debido a la competencia entre cationes y el efecto de la disponibilidad de los micronutrientes. En los sistemas agrícola y plantación de eucalipto se presentó una disminución en K, Fe, Mn, Zn y CIC, mientras que en el pastizal los contenidos de P y K aumentaron a diferencia del matorral que representa la vegetación natural.
CALCULATING MODEL FOR THE FRICTION DRAG OF A SHIP’S HULL
Authors: ANDREI VIOREL , RODICICHIN NICOLETA-GABRIELA 
Published: October 2018

<p>This paper presents the contribution of the authors regarding the friction drag calculation of a ship’s hull using the quasi-plane model. The velocity calculation by a dimensional model helps to determine the friction tangential effort. Then, by integration, can be determined the friction drag of a rectangular plane panel. By extension over all the plane plates which compose the ship’s side, results the friction drag for entire ship’s side.</p><p> </p>
ANALYSIS OF THE SURFACE QUALITY OF PARTS PROCESSED BY SINGLE POINT INCREMENTAL FORMING
Authors: RADU CRINA , HERGHELEGIU EUGEN , CRISTEA ION , SCHNAKOVSZKY CAROL 
Published: October 2018

<p>The aim of the current work was to analyse the influence of the process parameters (tool diameter, size of the vertical step of tool, feed rate and spindle speed) on the quality of the processed surface, expressed in terms of roughness and macrostructure in the case of parts processed by single point incremental forming. The analysis was made on A1050 aluminium metal sheets. The obtained results revealed that the process parameters influence differently the surface quality, the worst influence being exerted by the increase of the vertical step of tool. </p>
PROPOSALS FOR STRATEGIES IN THE CURRICULA OF TECHNICAL UNIVERSITIES
Authors: ZICHIL VALENTIN , NEDEFF VALENTIN , SCHNAKOVSZKY CAROL , DROB CĂTĂLIN 
Published: October 2018

<p>Into the past 20 years, in Romania is registered a continuous decrease of the birth rate. At this problem it has to be added the youth wish to work in economics and laws systems, where the length of time study is smaller (only 3 years), gaining the possibility to own rapidly a salary. In those conditions, technical universities have to challenge greater provocations. The paper propose a solution, partially applied in “Vasile Alecsandri” University of Bacau, to solve some of these new problems using a few solutions such as: “virtual” higher education and distance learning methods in order to achieve as much as is possible from the goals presented in known theories of career development. In the mean time, the strategy of the staff is presented, to make the university attractive for the youth, in order to continue the educational activity and to form better and better qualified specialists, able to face the new techniques technologies in manufacturing and product analysis. A model of curricula for the first two academic years in technical high schools is proposed.</p>
EXPERIMENTAL RESEARCH REGARDING THE INFLUENCE OF THE FRICTION FORCE FROM LINEAR ROLLING GUIDEWAYS ON THE POSITIONING PRECISION OF KINEMATIC FEED CHAINS USED ON CNC MACHINE TOOLS
Authors: FUNARU MARIAN , STAN GHEORGHE 
Published: October 2018

<p>Friction represents one of the major sources of disturbing forces which affect the functioning of the kinematic feed chains from CNC machine tools. Its influence reflects on the positioning precision values, having a negative impact on the table movement and leading to stationary errors, stick-slip motion and trajectory errors. The present paper presents an experimental analysis regarding the influence of the friction forces which appear in the linear rolling guideways on the positioning precision of kinematic feed chains. The rolling guideways present the advantages of a good behavior in terms of axis stability at low speeds and also for achieving high positioning speeds. Concerning the friction coefficient values, rolling and hydrostatic guideways are most suitable for the construction of high speed and high precision kinematic feed chains; in these cases, the friction coefficient has small values, which maintain quasi-constant against the feed rate. </p>
FITTING AN ELLIPSE TO THE SET OF INTENSITY DATA POINTS OF VRANCEA EARTHQUAKES
Authors: BURTIEV RASHID 
Published: October 2018

<p>Fitting an ellipse to the set of intensity data points of earthquakes occurred on 11.10.1940, 07.04.1977, 31.08.1986, 30.05.1990 and 31.05.1990 is performed. Test criteria indicate that the ellipse smoothes the observed line of macroseismic field. For all earthquakes, focal axes of 5, 6 and 7 EMS-98 intensity zones are directed along the y-axis. For other zones are oriented along the parallels. This fact is one more acknowledgement of the anisotropy of a geophysical medium. Approximation of the set of points with an ellipse is performed using the method proposed by Fitzgibbon. </p>
MANAGING THE ENVIRONMENTAL HAZARDS OF WASTE TIRES
Authors: KORDOGHLI SANA , PARASCHIV MARIA , KUNCSER RADU , TAZEROUT MOHAND , PRISECARU MALINA , ZAGROUBA FETHI , GEORGESCU IONUT 
Published: October 2018

<p>This paper presents an experimental approach on understanding and managing the environmental hazards of co-products resulted during energy recovery processes applied on scrap tires. As tire combustion faces serious problems related to harmful emissions, pyrolysis appear as a process that allow the management of toxic compounds.</p><p>Thus, for the reactions that occur during pyrolysis and combustion of tires organic matters the main intensive degradation thermal ranges have been established. The work was carried out by coupling thermogravimetric analysis (TGA) of tire samples with bench scale reactor in order to identify the relationships between thermochemical behaviour and products distribution. </p>
DETERMINING DYNAMIC ACCURACY INDICATORS OF MULTICOORDINATE WORKING MACHINES IN THE FORM OF ROD STRUCTURES FOR FUZZY INERTIA AND DISSIPATION PARAMETERS
Authors: STRUTYNSKIY VASYL , KOZLOV LEONID 
Published: October 2018

<p>The paper considers<strong> </strong>a manipulator design and its dynamic model developed by the authors. On the basis of this dynamic model a mathematical model of the manipulator has been created, which enables its spatial motion investigation. The mathematical model takes into account the manipulator inertia tensor with fuzzy components. The developed computation procedure makes it possible to determine cross-angular displacements of the manipulator for impact and sinusoidal laws of torque variation. During random variations of the moment of external forces, complex cross-angular displacements of the manipulator occur. The displacement trajectory includes an elliptical region that corresponds to the ellipse of the manipulator elastic system stiffness. The range of the manipulator upper-end displacement trajectory is maximal in the direction close to that of minimal cross-angular stiffness of the manipulator elastic system.</p>
THE EFFECT OF WATER HARDNESS ON RHEOLOGICAL BEHAVIOR OF DOUGH
Authors: ȘTEFAN ELENA-MĂDĂLINA , VOICU GHEORGHE , CONSTANTIN GABRIEL-ALEXANDRU , FERDEȘ MARIANA , MUSCALU GHEORGHE 
Published: October 2018

<p>Flour and water are basic components in dough formation process. The water quality affects the whole breadmaking process and the quality and retention period of bakery products. In bakery, an important role is played by the hardness of water; are preferred water having a hardness by 5 - 10<sup>o</sup> D (German degrees) and, in some cases, are preferred the waters with 10 – 20<sup>o</sup> D, depending on the characteristics of gluten. For the experimental determination, presented in this paper, were used samples of FA 650 flour type (white flour) and four kinds of water with different hardness values. To determine the dough rheological characteristics were made measurements according to AACC 54-21 standard method, using the Brabender Farinograph-E model (300 g mixer capacity). </p>The paper presents the study of rheological characteristics variation of wheat flour dough, depending on the water hardness used in mixing and formation process.
GEOMORPHOLOGICAL CHANGES IN BUCHAREST CITY OVER THE LAST 150 YEARS
Authors: GHEORGHE DIANA , ARMAŞ IULIANA 
Published: October 2018

<p class="yiv776123426msonormal"><span lang="EN-US">Bucharest, the capital of Romania, is situated in the Romanian Plain and is being drained by Dambovita and Colentina Rivers. During the last 150 years, the natural landscape has been intensely modified by its inhabitants. The most prominent change has been made in the Dambovita floodplain, where the natural land features have been completely changed. The present paper aims to highlight the major geomorphological changes that Bucharest suffered over the last 150 years. The major human intervention was the improvement of Dambovita channel and the demolition and/or the construction of different buildings during the communist period. Besides the human induced geomorphological changes, there is also soil creeping as a natural geomorphological phenomenon that shapes the landscapes of Bucharest. </span></p>
A MULTICRITERIA DESCRIPTION OF RULES FOR PUBLIC PROCUREMENT
Authors: ŽIŽOVIĆ MALIŠA , ŽIVKOVIĆ MILUTIN 
Published: October 2018

<p>At an announced tender of a contracting party, in the processes of public procurement of goods or services, a method of decision-making follows after interested bidders submit bids. Such method of choice is characteristic for all business systems with majority share of state capital. Methods of decision-making come down to selecting the best bids, because mistakes in the selection should be excluded. However, in practice, the problems of a wrong choice are manifested in dissatisfaction of the bidders. The problem then causes a delay in the procurement process, and often the retrial. In order to prevent this from happening authors of this paper suggest a somewhat different methodologies in selecting the most advantageous tender to the contracting authorities. The proposed method will be the case of the of Parking service (PC) from Belgrade (service of overhaul of the devices) will show a possible way of selecting the best alternative bids, taking into account previously adopted criteria.</p><p> </p>
El prestigio social de la profesión según los futuros docentes de Educación Primaria y Secundaria
Authors: Martínez de la Hidalga de la Torriente Zoe , Villardón-Gallego Lourdes 
Published: October 2018

Resumen:El prestigio social de la profesión docente es un factor que afecta a la configuración de la identidad del docente y a la calidad educativa. Esta investigación tiene como objetivo analizar la percepción que los estudiantes del Grado en Educación Primaria (GEP) y del Máster en Formación del Profesorado de Educación Secundaria (MES) tienen sobre la imagen social del profesor. Han participado en la investigación estudiantes del GEP, 147 de primer curso y 117 de cuarto y estudiantes del MES, 59 en el inicio de los estudios y 52 a su finalización. De ellos, 44 estudiantes respondieron en ambos momentos. La consideración que los estudiantes tienen sobre el prestigio de la profesión evoluciona a lo largo de la formación inicial, siendo cada vez más conscientes de que está infravalorada. Las razones que los estudiantes argumentan para explicar la escasa consideración social del docente giran en torno a tres ideas: insuficiente impacto social, buenas condiciones laborales, sencillez tanto de las tareas y funciones que desempeñan como de los requisitos académicos para conseguir la certificación. Los resultados tienen implicaciones para la formación inicial del profesorado y para la calidad de la educación. Abstract:Teachers’ social prestige is a factor that affects teachers’ identity and quality of education. This research aims to analyze education undergraduate and master students’ perception about the teacher’s social image. Participants in this research were 147 first year and 117 fourth year Undergraduate students in Primary Education, and 59 Master’s students in Secondary Education at the beginning of the course and 52 at the end. Among them, 44 students participated in both moments. Students’ perception about the prestige of the teaching profession develops over the initial teacher training towards a greater awareness of its undervalued status. The reasons provided by the students to explain the low social status of the teacher deal with three main ideas: a) lacking social impact; b) positive working conditions; c) simplicity of teachers’ tasks and responsibilities as well as of the academic requirements for their qualifications. Our results have implications for the initial teacher training as well as for the quality of the education.
Diseño y validación de un cuestionario para la alfabetización ambiental del profesorado de Primaria en formación inicial
Authors: Álvarez-García Olaya , Sureda-Negre Jaume , Comas-Forgas Rubén 
Published: October 2018

Resumen:La formación del profesorado en Educación Ambiental (EA) es fundamental para posibilitar la formación de una ciudadanía ambientalmente educada. En el presente artículo se describe el proceso seguido para el diseño y la validación de un instrumento con el que evaluar las competencias ambientales del alumnado del Grado de Maestro/a de Primaria. En una primera fase se analizaron y determinaron las competencias básicas que deben ser evaluadas entre este alumnado a partir del concepto de “alfabetización ambiental” y la literatura científica existente sobre el tema. Delimitadas dichas competencias, se definieron las variables de análisis y se elaboraron los ítems con los que se medirían cada una de estas competencias. Mediante el juicio y criterio de un panel de expertos/as en EA se validó el contenido del cuestionario. Para aplicar las pruebas de confiabilidad estadística se llevó a cabo una prueba piloto del instrumento. Como resultado se obtuvo un cuestionario validado y fiable conformado por 89 ítems con el que poder evaluar y determinar las competencias ambientales del profesorado de primaria en formación inicial -adaptable a otros colectivos de similares características. Abstract:Teacher training in Environmental Education (EE) is essential to ensure the development of an environmentally literate citizenry. In this article, we describe the process followed for the design and validation of an instrument to assess the environmental competencies of primary pre-service teachers. In a first phase the basic competencies that should be assessed among these students were determined according to the concept of "environmental literacy" and the existing scientific literature on the topic. Once delimited these competencies, the analysis variables were defined and the items that would be measured with each of these competencies were developed. Following the opinion and judgement by a panel of experts in EE the content of the questionnaire was validated. To apply statistical reliability testing, a pilot test was conducted. As a result, a validated and reliable questionnaire composed of 89 items with which to evaluate and determine the environmental competences of primary teachers in initial training -adaptable to other groups of similar characteristics- was obtained.