bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diabetes Discharge Planning and Transitions of Care: A Focused Review
Authors: Black Robin L. , Duval Courtney 
Published: July 2018

Background:
Diabetes is a growing problem in the United States. Increasing hospital admissions
for diabetes patients demonstrate the need for evidence-based care of diabetes patients by inpatient
providers, as well as the importance of continuity of care when transitioning patients from inpatient
to outpatient providers.

Methods:
A focused literature review of discharge planning and transitions of care in diabetes, conducted
in PubMed is presented. Studies were selected for inclusion based on content focusing on transitions
of care in diabetes, risk factors for readmission, the impact of inpatient diabetes education on patient
outcomes, and optimal medication management of diabetes during care transitions. American Diabetes
Association (ADA) guidelines for care of patients during the discharge process are presented, as
well as considerations for designing treatment regimens for a hospitalized patient transitioning to various
care settings.

Results:
Multiple factors may make transitions of care difficult, including poor communication, poor
patient education, inappropriate follow-up, and clinically complex patients. ADA recommendations
provide guidance, but an individualized approach for medication management is needed. Use of scoring
systems may help identify patients at higher risk for readmission. Good communication with patients
and outpatient providers is needed to prevent patient harm. A team-based approach is needed, utilizing
the skills of inpatient and outpatient providers, diabetes educators, nurses, and pharmacists.

Conclusion:
Structured discharge planning per guideline recommendations can help improve transitions
in care for patients with diabetes. A team based, patient-centered approach can help improve patient
outcomes by reducing medication errors, delay of care, and hospital readmissions.
Chronic Kidney Disease and Cardiovascular Disease: Is there Any Relationship?
Authors: Vallianou Natalia G. , Mitesh Shah , Gkogkou Agathoniki , Geladari Eleni 
Published: July 2018

Introduction:Chronic Kidney Disease is a growing health burden world wide. Traditional and mutual risk factors between CVD and CKD are age, hypertension, diabetes mellitus, dyslipidemia, tobacco use, family history and male gender. In this review, we will focus on whether or not early CKD is an important risk factor for the presence, severity and progression of CVD. Specifically, we will examine both traditional and novel risk factors of both CKD and CVD and how they relate to each other.Conclusion:We will also assess if early treatment of CKD, intensive compared to standard, has an important effect on the halt of the development of CKD as well as CVD. Insights into the pathogenesis and early recognition of CKD as well as the importance of novel kidney biomarkers will be pointed out. Also, common pathogenetic mechanisms between CKD and CVD will be discussed.
Biological Activity, Structural Characterization and Crystal Packing of Chromane-Carboxylate Derivatives
Authors: Vrábel Viktor , Sivýb Július , Světlíkc Jan , Marchalínd Štefan , Peterd Šafař 
Published: July 2018

Abstract
We report here the crystal and molecular structure of a new chromane-derivative, namely isopropyl( 2R*,3S*,4S*)-4-(benzo[d]thiazol-2-ylamino)-2-hydroxy-2-ethylchromane-3-carboxylate (I), C21H22N2O4S, which crystallizes as racemate in the space group C2/c. Its structure has been solved using X-ray diffraction data obtained at low temperature (100(2) K). In this compound, the chromane moiety consists of a benzene ring fused with a six-membered heterocyclic ring which adopts a distorted half-chair conformation. The molecules are linked by a combination of O-H∙∙∙N and N-H∙∙∙O hydrogen bonds, resulting in a twodimensional network which helps stabilizing the crystal structure of the compound (I). Dihedral angle between the chromane and benzothiazol rings is 80.6(1)0.
Causes of Late Referral to the Emergency Department in Patients with Myocardial Infarction in Iran
Authors: Rad Mojtaba , Bidi Akram , Khaligh Gholam Reza , Rad Mostafa 
Published: July 2018

Abstract
Late referral of patients with myocardial infarction is one of the main causes of morbidity or mortality in these patients. Therefore, this study aimed to investigate the factors involved in the late referral of patients with heart attacks to the emergency department. A descriptive cross-sectional study was conducted on 148 patients with myocardial infarction referred to the emergency department. They were chosen using a census method. A researcher-made questionnaire was developed and assessed in terms of validity and reliability for data collection. Inclusion criteria included suffering from chest pain or other symptoms indicative of acute myocardial infarction, age above 18 years, tendency to take part in this study, patients with acute myocardial infarction who had late referral and were admitted to cardiac care unit for at least 48 hours. Data was analyzed using descriptive and inferential statistics via SPSS software. P < 0.05 denoted statistical significance. Pain improvement with rest (85.8%), severity of chest pain and lack of familiarity with the symptoms of heart diseases and abnormal cardiac symptoms (87.8%), confusion of heart problems with musculoskeletal problems (70.2%), and the presence of concomitant diabetes were important factors influencing late referral to the emergency department. The average time to reach the emergency department after the onset of the heart problem was 24 ± 3 hours. A lack of patients’ familiarity with cardiovascular symptoms and acute myocardial infarction calls the need to educate the society about symptoms and the need for an early referral to healthcare settings.
A case of synthetic cannabinoid poisoning in Croatia
Authors: Sutlović Davorka , Prkačin Ingrid , Vaiano Fabio , Bertol Elisabetta , Bratinčević Maja Veršić , Definis-Gojanović Marija 
Published: July 2018

Abstract
The number of new psychoactive substances (NPS), synthetic cannabinoids (SCs) in particular, is growing constantly. Because of the insufficiently explored effects on consumer health, they have become a major problem in the emergency departments. They are difficult to identify, and there are no antidotes that could reverse their detrimental effects. We report a case of poisoning of a young man who used SCs. The patient was admitted to the emergency department of the Clinical Hospital Merkur, Zagreb (Croatia) after sniffing and smoking a herbal product bought on the street. He presented with severe cognitive difficulties and visible eye redness. Other symptoms included somnolence, disorientation, loss of coordination, unsteady gait, hyporeflexia, stiffness, cramps and cold limbs, blurred vision, teeth grinding, dry mouth, tinnitus, fear, suicidal thoughts, impaired focus, memory, and speech, sedation, fatigue, depression, thought blocking, and autistic behaviour. His skin was dry, and his mucosa dry and irritated. Herbal products “Rainbow Special” and “Luminated Aroma” used by the patient were qualitatively analysed with gas chromatography / mass spectrometry (GC/MS) after direct extraction with an organic solvent. Solid-phase extraction method was used to analyse serum and urine samples. Despite the negative findings of biological samples, mostly due to the limitations of GC/MS, the clinical picture infallibly pointed to the poisoning with SCs. This was confirmed by the findings of 5-fluoro AMB (methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate) in the herbal products.
Oxidative stress, cholinesterase activity, and DNA damage in the liver, whole blood, and plasma of Wistar rats following a 28-day exposure to glyphosate
Authors: Milić Mirta , Žunec Suzana , Micek Vedran , Kašuba Vilena , Mikolić Anja , Lovaković Blanka Tariba , Semren Tanja Živković , Pavičić Ivan , Čermak Ana Marija Marjanović , Pizent Alica , Vrdoljak Ana Lucić , Valencia-Quintana Rafael , Sánchez-Alarcón Juana , Želježić Davor 
Published: July 2018

Abstract
In this 28 day-study, we evaluated the effects of herbicide glyphosate administered by gavage to Wistar rats at daily doses equivalent to 0.1 of the acceptable operator exposure level (AOEL), 0.5 of the consumer acceptable daily intake (ADI), 1.75 (corresponding to the chronic population-adjusted dose, cPAD), and 10 mg kg−1 body weight (bw) (corresponding to 100 times the AOEL). At the end of each treatment, the body and liver weights were measured and compared with their baseline values. DNA damage in leukocytes and liver tissue was estimated with the alkaline comet assay. Oxidative stress was evaluated using a battery of endpoints to establish lipid peroxidation via thiobarbituric reactive substances (TBARS) level, level of reactive oxygen species (ROS), glutathione (GSH) level, and the activity of glutathione peroxidase (GSH-Px). Total cholinesterase activity and the activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were also measured. The exposed animals gained less weight than control. Treatment resulted in significantly higher primary DNA damage in the liver cells and leukocytes. Glyphosate exposure significantly lowered TBARS in the liver of the AOEL, ADI, and cPAD groups, and in plasma in the AOEL and cPAD group. AChE was inhibited with all treatments, but the AOEL and ADI groups significantly differed from control. Total ChE and plasma/liver ROS/GSH levels did not significantly differ from control, except for the 35 % decrease in ChE in the AOEL and ADI groups and a significant drop in liver GSH in the cPAD and 100xAOEL groups. AOEL and ADI blood GSH-Px activity dropped significantly, but in the liver it significantly increased in the ADI, cPAD, and 100xAOEL groups vs. control. All these findings show that even exposure to low glyphosate levels can have serious adverse effects and points to a need to change the approach to risk assessment of low-level chronic/sub-chronic glyphosate exposure, where oxidative stress is not necessarily related to the genetic damage and AChE inhibition.
New insights into the organophosphate-induced intermediate syndrome
Authors: Haliga Raluca Ecaterina , Morarasu Bianca Codrina , Ursaru Manuela , Irimioaia Viorica , Sorodoc Laurentiu 
Published: July 2018

Abstract
Acute organophosphate (OP) poisoning can be deadlier than any other type of chemical poisoning. So far, only a few cases have been described that include extensive neurological complications. We present an outstanding case of severe oral OP poisoning with intermediate syndrome developed on the fourth day after hospital admission. The clinical picture involved weakness of the proximal upper and lower limb muscles and several muscles supplied by motor cranial nerves, but, what is peculiar, the distal upper and lower limb muscles were also affected (forearms, hands, legs, and feet). To our knowledge, this is a unique presentation, as lower limb muscle weakness was reported only in the context of delayed polyneuropathy. Another remarkable feature was the involvement of six of the twelve cranial nerves, which makes this case of intermediate syndrome the first with such a spread of muscle weakness and provides new insights into the polymorphic clinical manifestations of acute OP poisoning.
Phenolic Content from Medicinal Plants and their Products Used in Veterinary Medicine
Authors: Varga Erzsebet , Schmidt Ibolya , Szövérfi Beáta , Pop Mădălina Daniela , Kelemen Hajnal , Tóth Anita 
Published: July 2018

Abstract

Objective: The aim of the study was to determine the content of polyphenols and flavonoids from sixteen selected medicinal plants from the spontaneous Romanian flora and fifteen tinctures obtained with propylene glycol.

Methods: The polyphenols were determined by the Folin-Ciocalteu method while the flavonoids by using a colorimetric method from the 10th edition of the Romanian Pharmacopoeia. The antioxidant activities of the most common nine medicinal plants and fifteen tinctures were determined by DPPH and ABTS methods.

Results: The results highlighted that the phenolic compounds and flavonoids have contributed to their antioxidant activities and the medicinal plants and tinctures included in the study are rich sources of natural antioxidants.

Conclusions: There are a wide variety of extraction methods for the determination of phenolics and flavonoids. The study confirms a correlation between phenolic and flavonoid contents obtained by using the DPPH and ABTS tests.
The Impact of Hard Brexit on Polish Exports
Authors: Borowski Jakub , Olipra Jakub , Błaszyński Paweł 
Published: July 2018

Abstract
The decision of the United Kingdom (UK) to leave the European Union (EU) is unprecedented, especially considering the recent trend in the global economy toward economic integration. There is a multitude of research concerning the implications of economic integration; however, research in the field of disintegration is scarce. Brexit serves as an interesting case study to investigate the effects of economic disintegration. The implications for trade are especially fascinating as trade liberalization is one of the most important benefits of economic integration. Existing studies focus mainly on Brexit’s impact on the UK’s exports and imports, while less attention has been paid to Brexit’s effects on the trade of other countries. The main objective of our research is to estimate Brexit’s influence on Polish exports. We present several possible scenarios of future trade relations between the UK and the EU and assume that, at least in the nearest-future post-Brexit scenario, trade under the World Trade Organization rules is most likely. This will result in the imposition of tariffs on trade between the UK and the EU members, including Poland. In our research, we used the real exchange rate of the Polish zloty against the British pound as a proxy for the changes in price competitiveness of Polish exports due to the imposition of tariffs. We find that in the first year after Brexit, the dynamics of Polish exports to the UK will decrease due to the imposition of customs duties by 1.3 percentage points (pp) and by 0.1 pp when it comes to total Polish exports. This paper contributes to the discussion on the effects of disintegration on trade. We propose a new method for assessing changes in trade volume due to increase of trade barriers.
Detection and molecular analysis of bovine enteric norovirus and nebovirus in Turkey
Authors: Turan Turhan , Işıdan Hakan , Atasoy Mustafa Ozan , Irehan Bünyamin 
Published: July 2018

Abstract

Introduction
Bovine Norovirus (BoNeV) which has been confirmed in Asia, America, and Europe, seems to be distributed worldwide, even though only reported from a number of countries. Bovine noroviruses are predominantly detected in diarrhoeic animals rather than neboviruses. The study reveals the importance of noro- and neboviruses in early age diarrhoea of calves.

Material and Methods
A total of 127 stool samples were collected from three provinces located in the central region of Turkey. Samples were subjected to nucleic acid isolation and reverse transcription and polymerase chain reaction (PCR). Positive samples were sequenced and analysed.

Results
According to PCR, five samples (3.93%) were found to be positive for bovine norovirus while 32 (25.19%) samples were found to be positive for bovine nebovirus. Phylogenetic analysis indicated that the novel Turkish norovirus strains were found to be of genotype III.2 and all novel neboviruses were substituted under Nebraska-like strains.

Conclusion
Although predominantly bovine noroviruses are detected worldwide, the study indicated that bovine neboviruses were more prevalent in the studied area. We suggest that bovine neboviruses are more frequently responsible for calf diarrhoea than supposed by virologists. This is also the first report of neboviruses other than Kirklareli virus which is distantly related to neboviruses detected in Turkey.
Effect of extender supplementation with low-molecular-weight antioxidants on selected quality parameters of cryopreserved canine spermatozoa
Authors: Lecewicz Marek , Strzeżek Rafał , Kordan Władysław , Majewska Anna 
Published: July 2018

Abstract

Introduction The addition of low-molecular-weight antioxidants during the freezing process improves post-thaw sperm quality. The high antioxidant potential of cryopreserved semen could have a positive effect on the motility, viability, and energy status of sperm cells and their ability to bind to the zona pellucida of oocytes. The aim of the study was to determine the effects of different concentrations and combinations of vitamins E and C in a semen extender on selected quality parameters of frozen-thawed canine spermatozoa.

Material and Methods The experimental material was the semen of four mixed-breed dogs. Sperm viability (motility, plasma membrane integrity, and mitochondrial function) was examined at 0, 60, and 120 min in semen samples supplemented with the extender and in the controls.

Results Combined supplementation with vitamins C + E at a concentration of 200 + 200 μM /1 × 109 spermatozoa had the most profound effect on total sperm motility, linear motility, and the percentage of spermatozoa with intact plasma membrane and active mitochondria.

Conclusion The synergistic activity of vitamins E and C had a more beneficial influence on the quality of frozen–thawed sperm than these non-enzymatic antioxidants applied separately.
Numerical Model of Plastic Destruction of Thick Steel Structural Elements
Authors: Kowalski Jakub , Kozak Janusz 
Published: July 2018

Abstract
In the shipbuilding industry, the risk of brittle fracture of the structure is limited by using certified materials with specified impact strength, determined by the Charpy method (for a given design temperature) and by supervising the welding processes (technology qualification, production supervision, non-destructive testing). For off-shore constructions, classical shipbuilding requirements may not be sufficient. Therefore, the regulations used in the construction of offshore structures require CTOD tests for steel and welded joints with a thickness greater than 40 mm in the case of high strength steel and more than 50 mm in the case of other steels. Classification societies do not accept CTOD test results of samples with a thickness less than the material tested. For this reason, the problem of theoretical modeling of steel structure destruction process is a key issue, because laboratory tests for elements with high thickness (in the order of 100 mm and more) with a notch are expensive (large samples, difficulties in notching), and often create implementation difficulties due to required high load and range of recorded parameters. The publication will show results and conclusions from numerical modeling of elastic properties for steel typical for offshore applications.
Calculations were carried out at the Academic Computer Centre in Gdańsk.
FEM Analysis and Experimental Tests of Rigid Riser Hanging System
Authors: Olszewski Artur , Wodtke Michał , Wójcikowski Artur 
Published: July 2018

Abstract
The article presents the analysis, project, and experimental examination of an original rigid riser for Coil Tubing Pipes. The principle of riser operation is based on the use of friction forces. The research included the FEM analysis of the designed riser, calculations of the required bolt tensions, and checking the effect of the clamping force on stress distribution in the pipeline. The results of computer simulation were verified on a specially designed test rig. The described riser design was implemented on the LOTOS Petrobaltic platform, thus eliminating the need for purchase and installation of expensive elastic risers.
Evaluation of “Stress Relief” Dietary Supplement on Animal Stress Level and Locomotion
Authors: Svirskis Šimons , Klimavičiusa Linda , Dzirkale Zane 
Published: July 2018

Abstract
Search of new approaches for harmless, non-medication treatment of body dysfunctions is still on the agenda of vet and human practitioners and researchers as well. This study presents evaluation of the effect of “Stress Relief” dietary supplement (SR) on mice behaviour under different acute short-term stress conditions and treatment duration. Five experiments were performed and in each 40 animals were randomly split into four (I–IV) groups, where I and II — non-stressed mice, III and IV — stressed animals, I and III received water with trace mineral solution (TMS), II and IV received water with SR. As stress factors, forced swimming, rodent predator odour or both together were applied. Locomotor activity under normal and stress conditions in Open Field were observed and measured by a SMART video-tracking system. Blood glucose level was measured as well. SR showed a reversal of stress-decreased locomotor activity in all stress models — distance walked increased almost twice (p < 0.0001), central zone crossings and time spent in it were 2–4 times greater than in the control group (p < 0.0001 and p = 0.0002, respectively), and fast movement episodes and maximal speed increased by 50–200%. In addition, complete normalisation of stress-induced elevation of blood glucose level (p < 0.0001) was noted. These results demonstrate for the first time that the effect of “Stress Relief” formula (water additives–minerals processed by know-how way in Vital Force Technology using Dr. Yury Kronn method) can be observed in laboratory animals, and that the effects are significant and repeatable. SR shows fear- and stress-reducing activity, which does not sufficiently differ between 7-, 9-, 14-, 28- and 32-day treatment regimes.
ANALYSIS AND EVALUATION OF IMPLEMENTATION OF UNDERGRADUATE NURSING CURRICULLUM FOR FAMILY NURSING IN WEST JAWA
Authors: Juniarti Neti , Sari Sheizi Prista , Yani Desy Indra 
Published: July 2018

Nurses are the backbone of the healthcare system, being the key providers of primary healthcare as they comprise 60-80% of the total health workforce, and provide 90% of all heath care services in the primary healthcare arena. This study aimed to evaluate the concordance of family nursing and community health nursing curriculum with international standards and national needs for undergraduate nursing education in West Java.This study used evaluation research design using BEKA framework as a tool to perform curriculum analysis which included Benchmarking, Evidencing, Knowing, and Applying stages. The international standards competency for family nursing and community health nursing, course study guide and samples of students reports were collected and analysed using content analysis. In addition participants from six nursing schools were interviewed to identify application of the curriculums. The results show that some of the competencies outlined in the course study guide were not aligned with international standards of family nursing from International Family Nursing Association. Four dimensional framework of family nursing and community health nursing curriculums were proposed to improve the alignment between international standards as well as local and government needs for family nursing and community health nursing curriculums. School of nursing can apply this framework as guidance to develop their own learning plans based on international standards, national, local and institutional needs. Keywords: curriculum analysis, evaluation, family nursing, community health nursing