bluuebunny/crossref_metadata_2025_split huggingface dataset:
Power Consumption Prediction Method for Train‐Health Monitoring Wireless Sensor Networks
Authors: Kawamura Tomoki , Ryuo Satoko , Iwasawa Nagateru 
Published: April 2018

SUMMARYIn recent years, much research has been conducted on the use of wireless sensor networks (WSN) for monitoring the conditions of railway vehicles. In WSNs for vehicle condition monitoring, the changes in the network configuration caused by both the coupling and decoupling of vehicles and communication environment changes resulting from vehicular motion make the power consumption of the sensor node unpredictable based on the existing approaches. In this paper, we propose a method of predicting the sensor node power consumption for WSNs used for vehicle condition monitoring based on the time‐series Monte Carlo method.
Reflections on the Journey of One Aspiring Culturally Responsive Evaluator—Thus Far
Authors: Hood Stafford 
Published: April 2018

AbstractStafford Hood acknowledges that he evaluates informally and formally based on his particular culture, personal background, family experiences, and responsibility he feels to serve others from throughout his life who put him in a position to do so. See the interview document here: http://onlinelibrary.wiley.com/wol1/doi/10.1002/ev.20311/suppinfo. Read only. This should not be used in any form without explicit permission from the author.
Genetic Mixture Analysis Supports Recalibration of the Fishery Regulation Assessment Model
Authors: Moran Paul , Dazey Joe , LaVoy Larrie , Young Sewall 
Published: April 2018

Abstract
Management of the commercially important Washington coastal Chinook Salmon Oncorhynchus tshawytscha troll fishery depends on the Chinook Salmon Fishery Regulation Assessment Model (FRAM). The Chinook Salmon FRAM uses historical and contemporary coded wire tag recoveries to estimate abundance and exploitation rates for particular indicator stocks. Those estimates are used to set limits on overall harvest and protect sensitive stocks. Current efforts are underway to implement a newer “base period” (time period on which exploitation rates are based). Our collaboration of science, management, and industry used genetic mixture modeling to provide independent stock composition estimates supporting FRAM recalibration. Genetic modeling suggested that total catch includes a much smaller proportion of a limiting Columbia River stock, a larger fraction of Canadian stocks, and an abundant Oregon coastal stock not previously included in the FRAM. Our results focus attention on particular stocks that will benefit from refinements in the Chinook Salmon FRAM.
Financial Conflicts of Interest at FDA Drug Advisory Committee Meetings
Authors: Hayes Michael J. , Prasad Vinay 
Published: April 2018

AbstractThe U.S. Food and Drug Administration's drug advisory committees provide expert assessments of the safety and efficacy of new therapies considered for approval. A committee hears from a variety of speakers, from six groups, including voting members of the committee, FDA staff members, employees of the pharmaceutical company seeking approval of a therapy, patient and consumer representatives, expert speakers invited by the company, and public participants. The committees convene at the request of the FDA when the risks and harms of novel products are not immediately clear, and their final decisions carry significant weight, as most therapies that receive advisory committee approval are subsequently approved by the FDA. In recent years, across a series of diverse publications, the financial conflicts of interest of each category of participants in the meetings have been investigated. Here, we summarize these findings and their ethical implications, focusing on the FDA Oncologic Drugs Advisory Committee, and we suggest ways to move toward more transparent and impartial advisory committee meetings.
Compromised Activation of Vitamin D After Elective Surgery: A Prospective Pilot Study
Authors: Blomberg Jensen Martin , Husted Henrik , Bjerrum Poul Jannik , Juul Anders , Kehlet Henrik 
Published: April 2018

ABSTRACTSurgical stress reduces concentrations of most proteins in serum and necessitates a rapid adjustment of hormones dependent on protein binding. Activation of vitamin D by renal 1α‐hydroxylation is dependent on protein binding because 1,25‐dihydroxyvitamin D (1,25(OH)2D3) is formed after megalin‐mediated reabsorption of 25‐hydroxyvitamin D (25OHD) bound to vitamin D binding protein (DBP). Postoperative alterations in serum concentrations of DBP and albumin may therefore impair 1,25(OH)2D3 production. Our objective was to determine sex‐specific changes in serum concentrations of vitamin D metabolites and sex steroids 2, 6, 24, and 48 hours and 3 weeks postoperatively. Fourteen women and eleven men aged 45 to 77 years without severe comorbidities undergoing unilateral total knee arthroplasty participated in this prospective study in a tertiary center for arthroplasty (trial ID: NCT02336932). The main outcome measures were total and free serum concentrations of 25OHD, 1,25(OH)2D3, 24,25‐dihydroxyvitamin‐D, DBP, albumin, sex hormone binding globulin (SHBG), calcium, and parathyroid hormone (PTH). Serum albumin and SHBG decreased postoperatively (Δalbumin48h −18% [−22%; −14%]). Unexpectedly, concentrations of DBP and 25OHD remained unaltered, but 1,25(OH)2D3 declined postoperatively. 1,25(OH)2D3 was 3 weeks after surgery −24% (−40%; −8%) lower than preoperative levels, whereas 24,25‐dihydroxyvitamin‐D remained unchanged in postmenopausal women. The calculated conversion rate of 25OHD to 1,25(OH)2D3 was strongly associated with serum 25‐OHD and PTH preoperatively, whereas serum calcium was most predictive postoperatively. In conclusion, surgery had no effect on serum concentrations of DBP, 25OHD, and PTH, whereas production of 1,25(OH)2D3 was markedly reduced. Further studies are needed to determine duration and putative outcome effects of this postoperative 1,25(OH)2D3 deficit in women, which in part may be due to discordance in CYP27B1 and CYP24A1 activity. © 2018 American Society for Bone and Mineral Research.
Conductometric Probe Analysis of the Effect of Benzyldimethylhexadecylammonium Chloride on the Micellization Behavior of Dodecyltrimethylammonium Bromide in Aqueous/Urea Solution: Investigation of Concentration and Temperature Effect
Authors: Molla Mohammad Robel , Rana Shahed , Rub Malik Abdul , Ahmed Anwar , Hoque Md. Anamul 
Published: April 2018

AbstractSurfactant mixtures are used in many different industrial formulations. In this study, the mixed micelle formation behavior of 2 different cationic surfactants, namely dodecyltrimethylammonium bromide (DTAB) and benzyldimethylhexadecylammonium chloride (BDHAC), in the absence and presence of urea at various temperatures (298.15–318.15 K) was studied using the conductometric method. The attractive interaction between DTAB and BDHAC was estimated from the values of critical micelle concentration (CMC) and the CMC for ideal mixing (CMCid). Urea increases the CMC value as a result of the enrichment in the surface charge of the micelles/mixed micelles. The values of micellar mole fraction (X1Rub [Rubingh], X1M [Motomura], X1Rod [Rodenas]) and ideal micellar (X1id) of surfactant BDHAC were obtained by different models and are shown to exhibit the high contribution or effective involvement of BDHAC in mixed micelles and increase with increasing BDHAC mole fraction (α1). Activity coefficients (f1 and f2) were also evaluated from the relevant formula given in the literature. The negative values of the interaction parameters (β) show the attractive interaction among the studied components. Excess Gibbs free energy (∆Gex) of micellization revealed that the stability of mixed micelles is higher in aqueous solution than in urea solution. The thermodynamic parameters, namely the Gibbs free energy change, enthalpy change, and entropy change (∆Gom, ΔHom, and ∆Som, respectively), were also calculated from the conventional standard equations.
Frequency‐based analysis of random fatigue loads: Models, hypotheses, reality
Authors: Benasciutti D. , Tovo R. 
Published: April 2018

AbstractSpectral methods use analytical expressions to estimate the fatigue damage in vibrating structures subjected to uniaxial or multiaxial random stresses. They exploit the random vibration theory which idealizes the random stress as a random process characterized by a power spectral density (PSD) in the frequency‐domain. The random process is hypothesized to be stationary or non‐stationary, Gaussian or non‐Gaussian, and with narrow‐band or wide‐band power spectral density. The accuracy of analytical spectral solutions depends on whether such hypotheses are fulfilled by actual random time‐histories encountered in practice. Knowing the range of applicability of each spectral method is then of utmost importance to avoid estimation errors. After a short account on the frequency‐domain description of random processes, this paper presents a brief survey on selected spectral methods for uniaxial and multiaxial random loading. It then analyzes when the hypotheses behind each spectral method are not verified in reality, with the purpose to provide recommendations for a safe use of frequency‐based methods.
AutoVOI: real‐time automatic prescription of volume‐of‐interest for single voxel spectroscopy
Authors: Park Young Woo , Deelchand Dinesh K. , Joers James M. , Hanna Brian , Berrington Adam , Gillen Joseph S. , Kantarci Kejal , Soher Brian J. , Barker Peter B. , Park HyunWook , Öz Gülin , Lenglet Christophe 
Published: April 2018

PurposeTo develop a fast and automated volume‐of‐interest (VOI) prescription pipeline (AutoVOI) for single‐voxel MRS that removes the need for manual VOI placement, allows flexible VOI planning in any brain region, and enables high inter‐ and intra‐subject consistency of VOI prescription.MethodsAutoVOI was designed to transfer pre‐defined VOIs from an atlas to the 3D anatomical data of the subject during the scan. The AutoVOI pipeline was optimized for consistency in VOI placement (precision), enhanced coverage of the targeted tissue (accuracy), and fast computation speed. The tool was evaluated against manual VOI placement using existing T1‐weighted data sets and corresponding VOI prescriptions. Finally, it was implemented on 2 scanner platforms to acquire MRS data from clinically relevant VOIs that span the cerebrum, cerebellum, and the brainstem.ResultsThe AutoVOI pipeline includes skull stripping, non‐linear registration of the atlas to the subject's brain, and computation of the VOI coordinates and angulations using a minimum oriented bounding box algorithm. When compared against manual prescription, AutoVOI showed higher intra‐ and inter‐subject spatial consistency, as quantified by generalized Dice coefficients (GDC), lower intra‐ and inter‐subject variability in tissue composition (gray matter, white matter, and cerebrospinal fluid) and higher or equal accuracy, as quantified by GDC of prescribed VOI with targeted tissues. High quality spectra were obtained on Siemens and Philips 3T systems from 6 automatically prescribed VOIs by the tool.ConclusionRobust automatic VOI prescription is feasible and can help facilitate clinical adoption of MRS by avoiding operator dependence of manual selection.
Der fluoreszierende Springbrunnen
Authors: Ducci Matthias 
Published: April 2018

AbstractDie Farbstoffe aus Tinten oder Textmarkern eignen sich als pH‐Indikatoren. Bei einem bewährten Experiment aus der Schulchemie erzeugen solche Moleküle zusammen mit einer UV‐Lampe grün oder blau leuchtende Fontänen.
Amphibian Response to Rotenone Treatment of Ten Alpine Lakes in Northwest Montana
Authors: Fried Lynda M. , Boyer Matthew C. , Brooks Meriel J. 
Published: April 2018

Abstract
The piscicide rotenone is an important and widely used management tool for native fish conservation; however, long-term empirical field studies investigating potential effects on nontarget species are lacking. We tested for effects of rotenone on four native amphibian species inhabiting 10 fish-bearing alpine lakes in northwest Montana. Visual encounter amphibian surveys were conducted for 2–4 years to establish baseline species-specific detection frequencies prior to piscicide treatment to eradicate nonnative trout. Species diversity and detection frequencies varied considerably among lakes, presumably due to differences in the amount of emergent vegetation. Comparisons between baseline detection frequencies and those established from posttreatment surveys consistently revealed no significant changes in amphibian detection frequency, suggesting resiliency of amphibian populations to these piscicide treatments. These results may be explained by one or more of the following: (1) timing the rotenone application when many amphibians had metamorphosed beyond the gill-breathing life stage; (2) application of rotenone at a concentration that was sublethal to amphibians; and (3) posttreatment immigration of adults from habitats not treated with rotenone. This study provides insight into the factors that contribute to amphibian population resiliency to alpine lake rotenone treatments within the context of a watershed-scale native trout restoration program.
Effect of a 5‐HT2c receptor agonist on urethral closure mechanisms in female rats
Authors: Ouchi Mifuka , Kitta Takeya , Kanno Yukiko , Higuchi Madoka , Togo Mio , Moriya Kimihiko , Shinohara Nobuo 
Published: April 2018

AimsThe serotonin (5‐HT2c) receptor is known to be involved in the mechanism of urethral closure in a model of stress incontinence. Lorcaserin (Belviq®) has received Food and Drug Administration approval for the treatment of obesity. However, it is unclear whether this selective 5‐HT2c receptor agonist enhances urethral closure in stress urinary incontinence (SUI) models. Therefore, we investigated whether lorcaserin could enhance urethral closure in female rats with vaginal distention (VD).MethodsNormal female rats and rats with stress incontinence induced by VD were tested. We evaluated the effect of a single dose of lorcaserin (0.03, 0.3, or 0.9 mg/kg with cumulative administration) on the urethral pressure amplitude during electrical stimulation (A‐URE) and on the urethral baseline pressure (UBP). The manual compression‐induced leak point pressure (LPP) was also measured.ResultsIn VD rats, a single intravenous injection of lorcaserin (0.3 and 0.9 mg/kg) significantly increased both A‐URE and LPP compared to saline (P < 0.05). In normal rats, intravenous lorcaserin (0.3 and 0.9 mg/kg) also significantly increased A‐URE and LPP compared to saline (P < 0.05). The changes of A‐URE and LPP, which are parameters of active urethral closure, were significantly larger in normal rats than in VD rats.ConclusionsWe showed that lorcaserin can activate the external urethral sphincter and pelvic floor muscles, suggesting an influence on active closure mechanisms. 5‐HT2c receptors agonists may have dual effects in patients with SUI, not only by reducing obesity but also by enhancing active urethral closure.
Sulfenamides as Building Blocks for Efficient Disulfide‐Based Self‐Healing Materials. A Quantum Chemical Study
Authors: Ruipérez Fernando , Galdeano Maialen , Gimenez Ekiñe , Matxain Jon M. 
Published: April 2018

AbstractThe theoretical self‐healing capacity of new sulfenamide‐based disulfides is estimated by using theoretical methods of quantum chemistry. Starting from previously studied aromatic disulfides, the influence of inserting a NH group between the disulfide and the phenyl ring (forming the sulfenamide), as well as the role of the phenyl ring in the self‐healing process is analyzed. Three parameters are used in the evaluation of the self‐healing capacity: i) the probability to generate sulfenyl radicals, which is the first step of the process; ii) the effect of the hydrogen bonding, which affects the mobility of the chains; and iii) the height of the exchange reaction barrier. The insertion of the NH group notably decreases the bond dissociation energy and, therefore, increases the probability to produce sulfenyl radicals and helps the approach of these radicals to neighboring disulfides, favoring the self‐healing process. The role of the phenyl rings is clearly observed in the reaction barriers, where the π–π stacking interactions notably stabilize the transition states, resulting in larger rate constants. Nevertheless, this stabilization is somewhat reduced in the aromatic sulfenamides, owing to a less effective π–π interaction. Therefore, the sulfenamide‐based aromatic disulfides may be considered as promising candidates for the design of efficient self‐healing materials.
Synthesis of Hydrocinnamaldehyde via Vapor Phase Dehydrogenation of Hydrocinnamyl alcohol over Rice‐Derived MgO‐Supported Copper Catalysts
Authors: Koppadi Kumara Swamy , Chada Raji Reddy , Gurram Venkata Ramesh Babu , Kancharakuntla Saidulu Reddy , Kamaraju Seetha Rama Rao , Burri David Raju 
Published: April 2018

AbstractGreen synthetic method for the production of hydrocinnamaldehyde via vapour phase dehydrogenation of hydrocinnnamyl alcohol over high surface area MgO (HSA‐MgO) supported Cu catalyst at atmospheric pressure without using any additives has been attempted. Cu/HSA‐MgO catalysts have been prepared by thermal decomposition of cooked rice grains mixed with magnesium acetate followed by wet impregnation by Cu. The prepared catalysts have been characterized by various physiochemical characterization techniques such as TGA, XRD, BET surface area, TPD of CO2, H2‐TPR, TEM, SEM, EDX and N2O pulse chemisorption. Among all the catalysts, 10%Cu/HSA‐MgO catalyst is found to be the best catalyst with 78% conversion of hydrocinnnamyl alcohol and 96% selectivity of hydrocinnamaldehyde. N2O pulse chemisorption and TPR analysis results divulge the high dispersion of smaller copper particles on the surface of HSA‐MgO support which is considered to be responsible for its superior catalytic activity.
Substituent Effects on Selective Syntheses of Fused‐Ring Heterocycles Based on Carbazole and Naphthalene by Photocyclization: Synthesis, Crystal Structures, and Properties
Authors: Luo Xin‐Yu , Liu Zhi , Zhang Bao‐Jie , Hua Wan‐Ming , Feng Ying , Li Li , Zhang Ding‐Chao , Cui De‐Liang 
Published: April 2018

AbstractTwo new different types of fused‐ring heterocycles based on the carbazole and naphthalene, that is, 10‐bromine‐7‐hexyl‐7‐monoaza[6]helicene (7) and 14‐hexyl‐11‐(thiophen‐2‐yl)‐14H‐phenanthro[4, 3‐b]carbazole (10) were successfully synthesized through the introduction of bromine and thiophene subtituents into 9‐Hexyl‐9‐carbazole‐3‐carbaldehyde. Their structures were fully characterized by 1H NMR, 13C NMR, mass spectroscopy and single‐crystal X‐ray diffraction pattern. Single‐crystal structures revealed that compound 10 possessed less distortion and deformation, and better planarity than compound 7. Compounds 7 and 10 had good solubility and thermal stability (Td = 236.82 °C for 7, Td = 214.96 °C for 10). These compounds had absorption maximum peaks at 319 nm for 7, 337 nm for 10, and emitted blue light with the peaks at 435 nm for 7, 447 nm for 10 in dichloromethane. The fluorescence quantum yields of compounds 7, 10 in different solvents were measured in the range of 8% ‐ 18%, 35% ‐ 74%, respectively. These results showed that introducing the functional substituent group of thiophene to the carbazole could not only transform photocyclization products from helicenes into other types of fused‐ring heterocyclic compounds but also increase the fluorescence quantum yields of compound 10 by more than three and half times. The simple synthetic method would pave the way for obtaining fused‐ring heterocycles with diverse types and various properties.
Comparing Immobilization, Recovery, and Stress Indicators Associated with Electric Fish Handling Gloves and a Portable Electrosedation System
Authors: Abrams Alice E. I. , Rous Andrew M. , Brooks Jill L. , Lawrence Michael J. , Midwood Jonathan D. , Doka Susan E. , Cooke Steven J. 
Published: April 2018

AbstractFish sedation facilitates safer handling of fish during scientific research or fisheries assessment practices, thus limiting risk of injury to fish and reducing stress responses. In recent years, there has been growing interest in using electricity to sedate fish; two methods include (1) lower‐voltage, non‐pulsed‐DC fish handling gloves (FHGs) that tend to only sedate fish while the gloves are touching the animal; and (2) a comparatively high‐voltage, pulsed‐DC Portable Electrosedation System (PES) that leads to galvanonarcosis. This study compared the physiological consequences of exposure to FHGs and PES in teleost fish. Bluegills Lepomis macrochirus and Largemouth Bass Micropterus salmoides were exposed to FHGs, PES, or a handling control for a 3‐min simulated surgery. Blood was then sampled at 0.5 and 4.5 h postexposure and was analyzed for blood glucose, blood lactate, and plasma cortisol concentrations. Opercular rates were monitored during surgery, at 2 min postsurgery, and 0.5 h postsurgery. At 24 h postsurgery, time to exhaustion (via a standardized swimming chase protocol) was assessed. Fish exposed to FHGs tended to exhibit lower opercular rates than fish that were sedated with the PES during simulated surgery. Cortisol levels of Largemouth Bass treated with FHGs were higher than those of fish sedated with the PES. Glucose levels recorded for Bluegills at 4.5 h postsurgery were higher with FHGs than with the PES. In both species, lactate was lower for fish treated with FHGs than for those treated with the PES. At 24 h posttreatment, Bluegills sedated with FHGs exhibited a longer time to exhaustion than those subjected to the PES, whereas Largemouth Bass sedated with the PES exhibited a longer time to exhaustion than those sedated with FHGs. Physiological responses to treatments were inconsistent between species. Further investigation to determine the optimal electrosedation method is required.
The rendering of human phenotype and rare diseases in ICD‐11
Authors: Chute Christopher G. 
Published: April 2018

AbstractICD‐11 (International Classification of Diseases, 11th Revision) is the next major revision of the ICD by the World Health Organization (WHO). ICD‐11 differs dramatically from historical versions, as it is based on an underlying semantic network of terms and meaning, called the Foundation. To function as a mutually exclusive and exhaustive statistical classification, ICD‐11 creates derivative linearizations from the network that is a monohierarchy with residual categories such as Not Elsewhere Classified. ICD‐11 also introduces the widespread post‐coordination of terms, which allows for highly expressive representation of detailed patient descriptions. Phenotyping features are included in many subchapters or the signs and symptoms chapter. Composite phenotype descriptions of specific presentations or syndromes can be represented though post‐coordination. Rare diseases are well represented in the Foundation, though not all appear in the relatively shallow linearization hierarchies.
Segregation-Assisted Plasticity in Ni-Based Superalloys
Authors: Barba D. , Smith T. M. , Miao J. , Mills M. J. , Reed R. C. 
Published: April 2018

Abstract
Correlative high-resolution transmission electron microscopy and energy-dispersive X-ray spectroscopy are used to study deformation-induced planar faults in the single-crystal superalloy MD2 crept at 800 °C and 650 MPa. Segregation of Cr and Co at microtwins, anti-phase boundaries (APB), and complex/superlattice extrinsic and intrinsic stacking faults (CESF/SESF and CISF/SISF) is confirmed and quantified. The extent of this is found to depend upon the fault type, being most pronounced for the APB. The CESF/SESF is studied in detail due to its role as a precursor of the microtwins causing the majority of plasticity under these conditions. Quantitative modeling is carried out to rationalize the findings; the experimental results are consistent with a greater predicted velocity for the lengthening of the CESF/SESF—compared with the other types of fault—and hence confirm its role in the diffusion-assisted plasticity needed for the microtwinning mechanism to be operative.