bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gaming-Based Tele-Exercise Program to Improve Physical Function in Frail Older Adults: Feasibility Randomized Controlled Trial
Authors: Kannan Lakshmi , Sahu Upasana , Subramaniam Savitha , Mehta Neha , Kaur Tanjeev , Hughes Susan , Bhatt Tanvi 
Published: November 2024

Background
Frailty leads to reduced physical activity can cause increased fall risk. This contributes to accelerated aging processes, leading to adverse health outcomes and reduced quality of life. We have developed and piloted the design, usability, safety, and feasibility of a gaming-based cognitive-motor (CogXergaming) tele-exercise protocol in prefrail older adults.

Objective
This pilot randomized control trial tested preliminary feasibility and effectiveness of the CogXergaming telehealth protocol for improving physical function.

Methods
Community-dwelling, prefrail older adults were randomly assigned to CogXergaming (n=13) or a control group (n=14). The CogXergaming group received supervised tele-exercises in a gaming format for 6 weeks (3 sessions per week) comprising 18 sessions lasting 90 minutes each. Control group participants participated in a Matter of Balance (MOB), an 8-week, once-a-week structured 90-minute tele-session that has been shown to reduce the fear of falling and increase physical activity. Feasibility of training was obtained by computing the median duration of training sessions for the CogXergaming group. Effectiveness was assessed using dynamic balance control (Four Square Step Test), subjective self-efficacy (Activities-Specific Balance Confidence scale), gait function (Tinetti Performance Oriented Mobility Assessment), muscle strength (30-second chair stand test), and endurance (2-minute step in-place test).

Results
Of the 45 participants enrolled in the study, 4 participants from CogXergaming group and 5 from MOB group lost contact after signing the consent form and did not receive their respective intervention. Eighteen participants were randomized to each group. In the CogXergaming group, 15 (83%) completed the intervention, with 3 (16%) dropping out in the first week. In the MOB group, 16 (88%) completed the program, with 2 (11%) withdrawing during the first week. In addition, there was a significant time group interaction for Four Square Step Test (F1,21=5.55, P=.03), Tinetti Performance Oriented Mobility Assessment (F1,25=4.16, P=.05), and 30-second chair stand test (F1,21=5.06, P=.03), with a significant improvement in these measures for the CogXergaming group post training, compared with no change observed in the MOB group.

Conclusions
These pilot findings indicate that CogXergaming is feasible and applicable in prefrail older adults. Such game-based protocols can be beneficial in improving physical function among community-dwelling, prefrail older adults, however, the efficacy of such training requires further investigation.

Trial Registration
ClinicalTrials.gov NCT04534686; https://clinicaltrials.gov/study/NCT04534686
Medication Management Initiatives Using Wearable Devices: Scoping Review
Authors: Iino Haru , Kizaki Hayato , Imai Shungo , Hori Satoko 
Published: November 2024

Abstract

Background
Wearable devices (WDs) have evolved beyond simple fitness trackers to sophisticated health monitors capable of measuring vital signs, such as heart rate and blood oxygen levels. Their application in health care, particularly medication management, is an emerging field poised to significantly enhance patient adherence to treatment regimens. Despite their widespread use and increasing incorporation into clinical trials, a comprehensive review of WDs in terms of medication adherence has not been conducted.

Objective
This study aimed to conduct a comprehensive scoping review to evaluate the impact of WDs on medication adherence across a variety of diseases, summarizing key research findings, outcomes, and challenges encountered.

Methods
Adhering to PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines, a structured search was conducted across MEDLINE, Web of Science, and Embase databases, covering the literature from January 1, 2010, to September 30, 2022. The search strategy was based on terms related to WDs and medication adherence, specifically focusing on empirical studies to ensure the inclusion of original research findings. Studies were selected based on their relevance to medication adherence, usage of WDs in detecting medication-taking actions, and their role in integrated medication management systems.

Results
We screened 657 articles and identified 18 articles. The identified studies demonstrated the diverse applications of WDs in enhancing medication adherence across diseases such as Parkinson disease, diabetes, and cardiovascular conditions. The geographical distribution and publication years of these studies indicate a growing interest in this research area. The studies were divided into three types: (1) studies reporting a correlation between data from WDs or their usage and medication adherence or drug usage as outcomes, (2) studies using WDs to detect the act of medication-taking itself, and (3) studies proposing an integrated medication management system that uses WDs in managing medication.

Conclusions
WDs are increasingly being recognized for their potential to enhance medication management and adherence. This review underscores the need for further empirical research to validate the effectiveness of WDs in real-life settings and explore their use in predicting adherence based on activity rhythms and activities. Despite technological advancements, challenges remain regarding the integration of WDs into routine clinical practice. Future research should focus on leveraging the comprehensive data provided by WDs to develop personalized medication management strategies that can improve patient outcomes.
Optimization of fulvic acids production from oil palm empty fruit bunches using microwave extractor
Authors: Dimawarnita Firda , Maharani Khairy Yunda , Faramitha Yora , Kalbuadi Donny Nugroho , Prakoso Haryo Tejo , Sari Indah Puspita , Prasetyo Dedy , Sutanto Sutanto , Goenadi Didiek Hadjar 
Published: November 2024

Fulvic acid (FA) derives from a non-renewable source, Shilajit, known as highly commercial values for its benefit for human health. Fulvic acid can also be extracted from materials such as coal, lignite, and peat. Extraction methods of FA generally use solid acids and bases, ion exchange chromatography, and their combinations. However, these methods cause corrosion, low purity, and environmental pollution. The FA extraction using organic solvents is common, but low yielded, and many organic solvents are toxic. Therefore, an effective way to separate organic solvents from FA must be determined. This research aims to extract the FA from renewable biomass, namely oil palm empty fruit bunches (OPEFB), using a microwave extractor combined with hydrogen peroxide. The advantage of using a microwave is its quick and efficient extraction process. Hydrogen peroxide is an environmentally friendly solvent that can be converted into water and oxygen. Fulvic acid extraction was optimized using expert design with the Response Surface Methodology method with optimization of four 4 factors (H2O2 concentration and volume, reaction time, and microwave power). The extracted FA was then characterized using FTIR, H-NMR, and Fluorescennce spectroscopy. The highest FA concentration namely 24.716%, was obtained using H2O2 at a concentration of 30.46% with a volume of 137.4139 mL, reaction time of 9.384 minutes, and microwave power of 351.39 W. Fourier-Transform Infrared Spectroscopy peaks at 3213 cm-1, 2935.47 cm-1, and 2825.13 cm-1 in the OPEFB-FA sample indicate existence of FA. The fluorescent emission intensity ratio between 450/500 nm wavelengths of OPEFB-FA was 0.719.
O que é estar presente no processo de ensino à distância?
Authors: Rocha de Siqueira Isabel , Candido Da Silva Lau Nycolas 
Published: November 2024

O que o ensino à distância trouxe para a sala de aula foi uma ruptura, em muitos casos, mas ele também nos provocou a investir ainda mais em formatos e processos. No caso das Relações Internacionais, uma disciplina cuja formação não pressupõe treinamento pedagógico, a pandemia talvez represente um ponto de inflexão importante. Propomos pensar três “interstícios” na medida em que indagam o que significa estar presente na sala de aula. Tratamos da maneira como a arquitetura digital em que nos inserimos nos divide em parcelas de informação e sobre qual é o papel da prática pedagógica em desafiar essa forma de existência digital, mesmo em tempos de ensino remoto. Falamos também do papel das narrativas como formas de promover contiguidade, clamando por uma presença qualificada na conversa. Por último, olhamos para como o ensino pode ser atravessado por construções de imaginários alternativos de tais modos a garantir presença nessa construção. Para todas essas reflexões, oferecemos casos de atividades “em sala” para o prolongamento dessa contiguidade em termos de uma descompressão de arcos narrativos, ou seja, em desafio ao engajamento por vezes divisivo e superficial dos tempos digitais.
Reglene om global minimumsbeskatning: Rederiskatteordningens undergang eller redning?
Authors: Torvanger Tormod 
Published: November 2024

Artikkelen gir en oversikt over virkningene av den nye norske skatteloven som implementerer Pilar 2-regelen om global minsteskatt i norsk skatterett for selskaper som omfattes av den norske rederiskatteordningen. Den nye lovgivningen, som er basert på det såkalte Pillar 2-modellregelverket som er utviklet av OECD/G20, skal sikre en minimum effektiv skattesats på 15 prosent for store multinasjonale foretak, herunder selskapsgrupper med enheter i Norge. Rederiskatteordningen fritar på den annen side selskap som omfattes av den fra beskatning av skipsfartsinntekter generelt. Selskap som omfattes av rederiskatteordningen er i stedet forpliktet til å betale en skatteart, som er basert på det aktuelle selskaps tonnasje. Denne skatteforpliktelsen er generelt sett mindre tyngende enn den skattebelastning som følger av det generelle bedriftsbeskatningsregimet. Selv om Pilar 2-regelsettet unntar inntekt vunnet ved «internasjonal skipsfart» fra sitt virkeområde, vil enkelte segmenter av skipsnæringen som i dag omfattes av tonnasjeskattesystemet, bl.a. store deler av offshore shippingindustrien, bli rammet det nye regelsettet. Derfor vil skattesituasjonen for disse segmentene av næringen – i hvert fall i prinsippet – bli skjerpet under det nye regelverket. Artikkelen argumenterer for at det nye regelsettet, i et bredere perspektiv, likevel kan være gunstig for skipsfartsnæringen.
Abstract in English
Rules for Global Minimum Taxation: The Shipping Tax System's Downfall or Rescue?This article provides an overview of the
effects for companies comprised by the Norwegian tonnage tax system of the new Norwegian Tax Act implementing the Pillar 2 rule set concerning global minimum tax in Norwegian tax law. The new legislation, which is based on the Pillar 2 Models Rules as developed by OECD/G20 Inclusive Framework, shall ensure a minimum effective tax rate of 15 percent for large multinational enterprises, hereunder groups of companies with entities in Norway. The tonnage tax system does, on the other hand, exempt companies comprised by it from taxation of shipping income in general. Instead, companies comprised by the tonnage tax system are obliged to pay a tax based on their tonnage, which generally is less burdensome than the income tax obligation arising under the general corporate tax rule set. Although the Pillar 2 rule set exempts income from “international shipping” from its scope, certain segments of the shipping industry which currently are comprised by the tonnage tax system, i.a. large parts of the offshore shipping industry, will be comprised by the new rule set. Hence, the tax situation for these segments of the industry will – at least in principle – be tightened under the new rule set. Nonetheless, the article argues that the new rule set may be favorable for the shipping industry in a broader perspective.
Meningkatkan Kinerja Guru melalui Supervisi Pembelajaran di MTs Raudhatul Islamiyah Peniti Luar Tahun 2022/2023
Authors: Bakron Muhammad , Susila Rusmi 
Published: November 2024

Professionality of educators is determined by the height or low insight of teachers about the competence of educators. Increasing competence can be done with research involving collaboration with fellow educators. This study aims to determine the effectiveness of learning supervision by madrasa leaders. Specifically the purpose of this study is to improve teacher performance through learning supervision in MTs. Raudhatul Islamiyah Peniti Outside 2022. Inui research was designed using Classroom Action Research (CAR) from the stages of research obtained the following results: In cycles I and II, the first was obtained, teacher performance increased in making learning planning. Second, teacher performance increases in carrying out learning. Third, teacher performance increases in assessing student achievement. Fourth, teacher performance increases in carrying out the follow -up to the results of student learning achievement appraisal. Fifth, teacher performance increases in developing learning programs, carrying out learning, assessing learning achievement, and carrying out follow -up of student learning achievement results.

AbstrakProfesioanalitas pendidik ditentukan oleh tinggi atau rendahnya wawasan guru tentang kompetensi pendidik. Meningkatkan kompetensi dapat dilakukan dengan riset yang melibatkan kolaborasi dengan sesama pendidik. Penelitian ini bertujuan untuk mengetahui efektifitas supervisi pembelajaran oleh pimpinan madrasah. Secara spesifik tujuan dari penelitian ini adalah Peningkatan Kinerja Guru Melalui Supervisi Pembelajaran di MTs. Raudhatul Islamiyah Peniti Luar tahun 2022. Penelitian inui didesain menggunakan penelitian tindakan kelas (PTK) dari tahapan peneitian didapatkan hasil sebagai berikut: pada siklus I dan II, maka didapatkan pertama, kinerja guru meningkat dalam membuat perencanaan pembelajaran. Kedua, kinerja guru meningkat dalam melaksanakan pembelajaran. Ketiga, kinerja guru meningkat dalam menilai prestasi belajar siswa. Keempat, Kinerja guru meningkat dalam melaksanakan tindak lanjut hasil penilaian prestasi belajar peserta didik. Kelima, Kinerja guru meningkat dalam menyusun program pembelajaran, melaksanakan pembelajaran, menilai prestasi belajar, dan melaksanakan tindak lanjut hasil prestasi belajar siswa.
Kata kunci : Supervisi Pembelajaran, Peningkatan Kinerja, MTs Raudhatul Islamiyah
Barriers, Challenges and Considerations in Respondent-Driven Sampling with Women Victims of Intimate Partner Violence
Authors: Cardona Paula Andrea Díez , Arroyave Cristobal Ovidio Muñoz , Segura Angela María Cardona 
Published: November 2024

Introduction: Gender violence by a partner is a reality that has been addressed in recent decades. Accessing to this population can be a challenging issue for the researcher, due to there are only sample frames of women who have reported violence, losing sight of those who have been victims but due to various personal, social, cultural circumstances, among others, do not have done the police report. In this way, gender violence by a partner is an underestimated phenomenon.

The objective: of this article was to qualitatively describe the barriers, challenges and considerations in recruiting Respondent-Driven Sampling with women who are victims of intimate partner violence, mostly unreported. Respondent-driven sampling (RDS) is a statistical alternative to snowball sampling, which allows access to visible and, especially hidden, populations.

Results: A total of 72 women were recruited for the study despite having initially set the goal of 95 women. The number of initial seeds and the deadline for applying instruments should had been extended in order to have greater participation. The challenges and barriers throughout sample collection and the resolution strategies used by the research team are shown.

Conclusion: The obstacles must be kept in mind when working with women who have experienced intimate partner violence by reason of they are a hidden population and difficult to access due to their characteristics. Women from all socioeconomic strata and educational levels were found Valle de Aburrá, Antioquia.
Energy Efficiency in Small and Medium-Sized Enterprises: a Literature Review Approach
Authors: Privat Fabrício Pereira , Guerrieri Daduí Cordeiro 
Published: November 2024

Objective: This research aims to analyze the leading publications on energy efficiency in small and medium-sized enterprises (SMEs) to present how the topic is being addressed in the literature.

Theoretical Framework: The worsening of global warming, resulting from the increased emission of greenhouse gases, has been widely observed. Industrial expansion activities and the increase in consumption of the world population significantly contribute to this phenomenon. In response, measures are being taken toward a more sustainable economy, and various studies have been addressing energy efficiency improvement to combine operational cost reduction and environmental impact reduction.

Methodology: A systematic literature review (SLR) was used to conduct this analysis. It identified and evaluated the leading publications on the topic, providing a comprehensive view of the techniques and solutions proposed for improving energy efficiency in SMEs.

Findings: The results revealed various techniques and solutions adaptable to SMEs despite financial and operational constraints. Common barriers include financial limitations, lack of technical knowledge, and resistance to change. With adequate support, SMEs might lead the transition to sustainable practices.

Implications: Implementing energy efficiency practices in SMEs can benefit both the global economy and the environment. Overcoming the identified barriers can enable these companies to significantly contribute to reducing environmental impacts, promoting a more sustainable and efficient economy.
Social Vulnerability and Illegal Occupation in Urban APP Areas: Legal and Environmental Perspectives in Brazil
Authors: Godoy Jeane Aparecida Rombi de , Benini Sandra Medina , Palmisano Angelo 
Published: November 2024

Objective: This study aims to critically investigate the conflicts generated by the illegal occupation of urban Permanent Preservation Areas (APPs) to analyze the tensions between environmental preservation and the social rights of vulnerable populations.

Theoretical Framework: The theoretical foundation is based on critical urbanization theories, as proposed by Lefebvre, Harvey, and Rolnik, which question socio-spatial segregation and the commodification of urban space, providing a solid basis for understanding the conflicts between environmental and social interests in urban areas.

Method: The methodology adopted for this research is qualitative, including case studies and analysis of secondary data, such as public policies on land regularization and relevant legal documents. These methods enable an in-depth analysis of the socio-spatial conditions in occupied APPs.

Results and Discussion: The results revealed the socio-spatial exclusion that drives marginalized groups to occupy environmentally sensitive areas. The discussion highlights the need for public policies that do not criminalize vulnerable populations but instead integrate housing and environmental preservation fairly. The limitations of the current legal framework and its implications are also discussed.

Research Implications: The implications of this research suggest a systemic change in urban public policies, directly influencing urban planning and environmental justice sectors. This study provides insights for the formulation of more inclusive and sustainable policies aligned with the principles of the right to the city and environmental justice.

Originality/Value: This study contributes to the literature by offering a critical analysis of conflicts in urban APPs, proposing alternatives that reconcile social justice and environmental preservation. The relevance of this work lies in its contribution to developing more equitable and effective public policies for environmentally sensitive areas in urban contexts.
Systematic Selection of Limonoids from Carapa Guianesis Aublet with Anti-Inflammatory Activity, Through in Silico Techniques for Topical Use
Authors: Barbora Júnior Raimundo Nonato da Silva , Reis André Silva dos , Andrade Eloisa Helena de Aguir , Silva José Rogério de Araújo , Santos Alberdan Silva 
Published: November 2024

Objective: The aim of this study is to investigate in silico the inhibitory activity of limonoids on the COX-1 enzyme and their liposolubility descriptors for topical actions against inflammation.

Theoretical Framework: Andiroba oil has limonoids with anti-inflammatory potential, highlighting their potential for sustainable bioeconomy due to their classification as non-steroidal. In this context, nine limonoid structures were studied in silico via molecular docking to the COX-1 enzyme.

Method: The 2D chemical structures of the limonoids were prepared using the MarvinSketch program, converted into 3D structures and optimized using classical mechanics methods. The structure of the COX-1 protein complexed with flurbiprofen in its active site was downloaded from the RCSB PDB of Homo sapiens origin and used for molecular docking using the Virtual Molegro Docker program.

Results and Discussion: The results obtained demonstrated that limonoids have the potential to inhibit COX-1. These results showed valuable information on liposolubility and COX-1 inhibitory activity, highlighting the potential for topical use of andirobas oil.

Research Implications: The practical and theoretical implications of this research emphasize that limonoids can inhibit COX-1 by preventing the formation of TXA2 thromboxanes, in addition to being associated with inhibition of platelet aggregation, being an effective measure in the prevention of arterial thrombosis, and which can be extended to vascular diseases, opening up perspectives for possible reduction, not only of microvaricose veins, but also of superficial phlebitis.

Originality/Value: This study contributes to the literature as it is an unprecedented study involving COX-1 and the limonoids present in andirobeira oil.