bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bioinspired Color Change through Guided Reflection
Authors: He Jiaqing , Song Chengyi , Shan Hao , Jiang Yiyue , Zhou Lingye , Tao Peng , Wu Jianbo , Shang Wen , Deng Tao 
Published: October 2018

AbstractColor change to match background has attracted particular attentions for many civil and military applications. Different from most current efforts in adaptive color change that include active color processing and generation, in this work a new passive color‐change approach without the need of color processing and generation is proposed. Such approach takes inspiration from the biological camouflage systems such as those in the midwater squid Galiteuthis, which use “leaky” fiber‐like cells to guide lights around their eyes for effective camouflage from their upward‐looking predators. In the approach, the bioinspired color‐change system directly takes the reflected light from the background, guides and displays it around the surface of the target. This bioinspired color‐change approach is dependent on a waveguide‐based system that includes light receiving, transporting, and display modules. Through the improvement of the efficiency in light collection, guiding, and display, both the experimental studies and computational modeling demonstrate the performance of such approach in the entire visible region with both spectra matching and rapid dynamic response. Through the design of pixelated modules, this new approach also shows good color matching with patterned color background and provides a feasible route to camouflage in a complex natural background.
Polarization Conversion Effect in Biological and Synthetic Photonic Diamond Structures
Authors: Wu Xia , Rodríguez‐Gallegos Fernando L. , Heep Marie‐Christin , Schwind Bertram , Li Guixin , Fabritius Helge‐Otto , von Freymann Georg , Förstner Jens 
Published: October 2018

AbstractPolarization of light is essential for some living organisms and many optical applications. Here, an orientation dependent polarization conversion effect is reported for light reflected from diamond‐structure‐based photonic crystals (D‐structure) inside the scales of a beetle, the weevil Entimus imperialis. When linearly polarized light propagates along its 〈100〉 directions, the D‐structure behaves analogous to a half‐wave plate in reflection but based on a different mechanism. The D‐structure rotates the polarization direction of linearly polarized light, and reflects circularly polarized light of both handednesses without changing it. This polarization effect is different from circular dichroism occurring in chiral biological photonic structures discovered before. The structural origin of this effect is symmetry breaking inside D‐structure's unit cell. This finding demonstrates that natural photonic structures can exploit multiple functionalities inherent to the design principles of their structural organization. Aiming at transferring the inherent polarization effect of the biological D‐structure to technically realizable materials, three simplified biomimetic structural models are derived and it is theoretically demonstrated that they retain the effect. Out of these structures, functioning woodpile structure prototypes are fabricated.
Design of a Simple and Practical Nanosystem Coordinates Tumor Targeting and Penetration for Improved Theranostics
Authors: Xiang Zhichu , Yang Xiaoliang , Jiang Gexuan , Fan Di , Geng Lingling , Wang Hao , Hu Zhiyuan , Fang Qiaojun 
Published: October 2018

AbstractA novel amphiphilic peptide PA (APPA) containing two functional motifs is designed to coordinate the targeting to integrin αvβ3 and neuropilin‐1(NRP‐1) on cell membrane. The cooperation of the two motifs fulfills the penetration of APPA‐based nanosystem deep into tumor tissue and accumulates there. The APPA can be easily synthesized and self‐assembled into spherical nanoparticles in the presence of doxorubicin (DOX) (PAD), or can be used for construction of fluorescent nanoprobe in the presence of DiR (PA‐DiR). In vitro and in vivo studies demonstrate that the self‐assembled PAD and PA‐DiR nanosystems show a surprisingly high affinity for and penetration into αvβ3 and NRP‐1 positive tumors. The PA‐DiR nanoprobe can be specifically recruited to 4T1 xenograft tumors. The signal of PA‐DiR enriched in the tumor was more than 10 times higher than that of the negative control PC‐DiR. The high affinity and specificity of the PA‐DiR nanoprobe in in vivo fluorescence imaging, the profound therapeutic efficacy of PAD nanosystem in solid tumor models, and the low toxicity of APPA‐based nanosystem demonstrate the great potential of this well‐designed and simple nanosystem for application in the diagnosis and therapy of αvβ3 and NRP‐1 positive tumors, with minimal side effects.
Thionine Functionalized 3D Graphene Aerogel: Combining Simplicity and Efficiency in Fabrication of a Metal‐Free Redox Supercapacitor
Authors: Shabangoli Yasin , Rahmanifar Mohammad S. , El‐Kady Maher F. , Noori Abolhassan , Mousavi Mir F. , Kaner Richard B. 
Published: October 2018

AbstractDiscovering efficient pseudocapacitive charge storage materials has become one of the grand challenges to reduce the gap between high energy density batteries and high power density and durable electrical double‐layer capacitors. This research direction is facilitated by the introduction of redox‐active species that add Faradaic charge storage to the system. However, the astonishing abilities of organic redox species to increase energy density are insufficient to compensate for their poor electrical conductivity and inferior cyclability. Herein, it is proposed that these challenges can be simultaneously met by thoughtful selection of a redox species, thionine, that can be conjugated to a 3D graphene aerogel as a substrate via π–π interactions. The as‐fabricated metal‐free symmetric device exhibits a very high specific capacitance of 384 F g−1 at 1 A g−1. Moreover, the device shows an ultrawide potential window of 2.0 V in pH‐neutral aqueous electrolytes and delivers a maximum specific energy of 32.6 Wh kg−1, specific power of up to 12.8 kW kg−1, outstanding flexibility, and an excellent capacitance retention of 91% after 10 000 charge–discharge cycles at 10 A g−1. This device design provides an effective strategy to fabricate high‐performance aqueous supercapacitors and facilitates progress toward a sustainable energy future.
Configuration Interaction and Many‐Body Perturbation Theory: Application to Scandium, Titanium, and Iodine
Authors: Imanbaeva Raykhan T. , Kozlov Mikhail G. 
Published: October 2018

AbstractA number of atoms and ions with complex valence configurations are considered as candidates for atomic clocks with high sensitivity to the possible variation of the fine‐structure constant. Present level of the theory is not sufficient to predict frequencies of the clock transitions with accuracy, required for the experiment. Here an approach is tested, where the second‐order perturbation theory is used to iteratively saturate configuration space for valence electrons. On the examples of scandium, titanium, and iodine, it is demonstrated that this improves the efficiency of the CI+MBPT method for systems with strong configuration interaction and/or more than three valence electrons.
Magnetic Phase Diagram of the Triangular Antiferromagnetic Cs2CuCl4−xBrx Mixed System
Authors: van Well Natalija , Zaharko Oksana , Delley Bernard , Skoulatos Markos , Georgii Robert , van Smaalen Sander , Rüegg Christian 
Published: October 2018

AbstractThe novel magnetic phase diagram of the Cs2CuCl4−xBrx mixed system is established by means of single crystal neutron diffraction in the lowest temperature region and zero magnetic field. Two long‐range ordered magnetic phases exist in this mixed system depending on the Cl/Br concentration. In the rich Cl concentration range, the ordered magnetic state occurs below the ordering temperature TN = 0.51(1) K for Cs2CuCl3Br1 and at Cs2CuCl2.6Br1.4 below TN = 0.24(2) K. Magnetic order with a temperature‐independent position (0, 0.573(1), 0) below the ordering temperature TN = 0.63(1) K appears in the rich Br concentration for Cs2CuCl0.6Br3.4. Between the rich Cl and rich Br concentration ranges (two magnetic phases), there is a range of x without magnetic order down to 50 mK. A suggestion about the magnetic exchange paths in the bc‐layer for different regimes is presented, which can be controlled depending on the preferred Br occupation in the [CuX4] tetrahedra. The density functional theory calculations of the exchange coupling constants J, J′ for some ordered compositions of the mixed system Cs2CuCl4−xBrx indicate that these are not frustrated.
Array‐basierte Sensorik mit der “chemischen Nase” in der Diagnostik und Wirkstoffentdeckung
Authors: Geng Yingying , Peveler William J. , Rotello Vincent M. 
Published: October 2018

AbstractArray‐basierte Sensorplattformen – “Chemische Nasen/Zungen” – sind inspiriert vom olfaktorischen System von Säugetieren. Multiple Sensorelemente in diesen Geräten interagieren selektiv mit Zielanalyten und produzieren dabei ein spezifisches Antwortmuster, wodurch sie die Identifikation von Analyten ermöglichen. Dieser Ansatz bietet einzigartige Möglichkeiten im Vergleich mit “traditionellen”, hoch‐spezifischen Sensorelementen, z. B. Antikörpern. Array‐basierte Sensoren sind herausragend, wenn es um die Identifikation kleiner Veränderungen in komplexen Mischungen geht, und ebendiese Fähigkeit wird nun in der chemischen Biologie und klinischen Pathologie genutzt, ermöglicht durch ein vielfältiges Instrumentarium neuer Molekular‐, Biokonjugat‐ und Nanomaterial‐Techniken. Innovationen beim Design und der Analyse der Arrays stellen ein robustes Instrumentarium für moderne biomedizinische Zielsetzungen, einschließlich der Präzisionsmedizin, zur Verfügung.
Growth Rate of Pressure‐Induced Triolein Crystals
Authors: Roßbach André , Bahr Leo A. , Gäbel Sebastian , Braeuer Andreas S. , Wierschem Andreas 
Published: October 2018

AbstractIn pressure‐induced crystal growth of triolein from melt at pressures up to 300 MPa and at temperatures between 283.16 and 293.16 K, we can distinguish three different crystal morphologies. Raman spectroscopy indicates that they are related to different polymorphic structures. Switching from the most stable to a less‐stable structure implies a jump in the growth rate to a maximum value. As pressure increases, the growth rate decreases indicating that the growth is transport limited. Measurements at different temperatures show that the growth rate is mainly governed by pressure. In a certain parameter range, we observe cross‐nucleation to crystals with a higher growth rate. These crystals have a Raman fingerprint not yet described in the literature.
Study on epoxy modification of HVBR and damping performance of EHVBR/hindered phenol hybrids
Authors: Liu Kai , Zhao Xuan , Li Peipei , Wang Zhaobo , Hua Jing 
Published: October 2018

ABSTRACTIn this study, epoxidized high vinyl polybutadiene rubber (EHVBR) was prepared by the epoxidation reaction of high vinyl polybutadiene rubber (HVBR) in toluene using peroxyacetic acid as oxidant. The effects of reaction temperature and peroxyacetic acid concentration on the epoxidation degree of EHVBR were investigated by Fourier transform infrared (FTIR) spectroscopy and nuclear magnetic resonance (NMR), and the damping properties of organic hybrids consisting of EHVBR and different contents of hindered phenols tetrakis [methylene‐3‐(3‐5‐di‐tert‐butyl‐4‐hydroxyphenyl) propionyloxy] methane (AO‐60) and 3,9‐bis[1,1‐dimethyl‐2{β‐(3‐tert‐butyl‐4‐hydroxy‐5‐methylphenyl)propionyloxy} ethyl]‐2,4,8,10‐tetraoxaspiro[5,5]undecane (AO‐80) were explored by dynamic mechanical analysis (DMA). FTIR and NMR analyses indicated that the epoxidation occurred on the C=C double bonds of HVBR molecular chains and the epoxidation degree of EHVBR could be adjusted from 5 to 65% through control of the reaction temperature and peroxyacetic acid concentration. DMA and physical mechanical measurements indicated that the introduction of AO‐60 and AO‐80 could simultaneously improve the damping properties and mechanical properties of the EHVBR/AO‐60 and EHVBR/AO‐80 hybrids. The blending ratios of EHVBR/AO‐60 = 100/60 and EHVBR/AO‐80 = 100/60 showed better damping properties and the effective damping temperature ranges were extended from 13.1 to 52.3 °C and from 16.1 to 54 °C, respectively. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47196.
Development of an organotypic stem cell model for the study of human embryonic palatal fusion
Authors: Wolf Cynthia J. , Belair David G. , Becker Carrie M. , Das Kaberi P. , Schmid Judith E. , Abbott Barbara D. 
Published: October 2018

BackgroundCleft palate (CP) is a common birth defect, occurring in an estimated 1 in 1,000 births worldwide. The secondary palate is formed by paired palatal shelves, consisting of a mesenchymal core with an outer layer of epithelial cells that grow toward each other, attach, and fuse. One of the mechanisms that can cause CP is failure of fusion, that is, failure to remove the epithelial seam between the palatal shelves to allow the mesenchyme confluence. Epidermal growth factor (EGF) plays an important role in palate growth and differentiation, while it may impede fusion.MethodsWe developed a 3D organotypic model using human mesenchymal and epithelial stem cells to mimic human embryonic palatal shelves, and tested the effects of human EGF (hEGF) on proliferation and fusion. Spheroids were generated from human umbilical‐derived mesenchymal stem cells (hMSCs) directed down an osteogenic lineage. Heterotypic spheroids, or organoids, were constructed by coating hMSC spheroids with extracellular matrix solution followed by a layer of human progenitor epithelial keratinocytes (hPEKs). Organoids were incubated in co‐culture medium with or without hEGF and assessed for cell proliferation and time to fusion.ResultsOsteogenic differentiation in hMSC spheroids was highest by Day 13. hEGF delayed fusion of organoids after 12 and 18 hr of contact. hEGF increased proliferation in organoids at 4 ng/ml, and proliferation was detected in hPEKs alone.ConclusionOur results show that this model of human palatal fusion appropriately mimics the morphology of the developing human palate and responds to hEGF as expected.
Compact Conjugated Polymer Dots with Covalently Incorporated Metalloporphyrins for Hypoxia Bioimaging
Authors: Fang Xiaofeng , Ju Bo , Liu Zhihe , Wang Fei , Xi Guan , Sun Zezhou , Chen Haobin , Sui Changxiang , Wang Mingxue , Wu Changfeng 
Published: October 2018

AbstractHypoxia is closely related to multiple diseases, especially in tumors, which increases the aggressiveness and drug resistance of cancer cells. Precise hypoxia imaging is of great significance for cancer diagnosis and the evaluation of therapeutic effects. A kind of hydrophobic polymer (i.e., PFPtTFPP) as an imaging probe for hypoxia with fluorene as an energy donor and an oxygen‐sensitive PtII porphyrin as an energy acceptor was developed. Compact polymer dots (Pdots) with a small size were prepared by nanoprecipitation. The PFPtTFPP Pdots showed excellent hypoxia sensing in solution with high sensitivity and full reversibility. The emission intensity, quantum yields, lifetime, and single‐particle brightness significantly increased under hypoxia conditions. Remarkably, hypoxia imaging in vitro and in vivo was realized, and a clear increase in brightness was observed under hypoxia conditions and in the tumor area. Excellent hypoxia imaging ability is beneficial to potential applications in cancer diagnosis.
Enhanced Binding Affinity of siRNA Overhang‐Binding Fluorescent Probes by Conjugation with Cationic Oligopeptides for Improved Analysis of the siRNA Delivery Process
Authors: Sato Yusuke , Kaneko Mitsumasa , Sato Takaya , Nakata Saki , Takahashi Yuki , Nishizawa Seiichi 
Published: October 2018

AbstractCarrier‐mediated delivery of small interfering RNAs (siRNAs) into the living cells is important for the realization of siRNA therapeutics that can silence target genes through RNA interference. We recently proposed a new strategy for analyzing the siRNA delivery process based on affinity labeling with a peptide nucleic acid (PNA)‐based fluorescent probe (PyAATO; Py: pyrene, A: adenine; TO: thiazole orange) capable of selectively binding to the overhanging structures of siRNAs. We have prepared new probes with improved binding affinity by conjugation with a cationic oligopeptide. The probe, carrying six lysine residues (PyAATO‐Lys6 (Lys6)), displayed a 39‐fold increase in affinity, compared with that of the parent probe containing no oligopeptides. Thermodynamic characterization revealed that enhanced affinity resulted from the favorable polyelectrolyte effect, due to the electrostatic interaction between lysine residues and phosphate anions of the RNA duplexes near the overhanging structure. Lys6 showed the improved imaging ability of the carrier‐mediated siRNA delivery process in living cells, in which 20 nm siRNA could be analyzed and was considered to show the minimal off‐target effects.
One‐year clinical performance of ABSORB bioresorbable vascular scaffold in patients presenting with acute coronary syndromes: Results from the RAI registry
Authors: Moscarella Elisabetta , Ielasi Alfonso , Varricchio Attilio , Cortese Bernardo , Loi Bruno , Tarantini Giuseppe , Pisano Francesco , Durante Alessandro , Pasquetto Giampaolo , Colombo Alessandro , Tumminello Gabriele , Moretti Luciano , Calabrò Paolo , Mazzarotto Pietro , Tespili Maurizio , Silva Orrego Pedro , Corrado Donatella , Steffenino Giuseppe ,   on Behalf of the RAI Investigators
Published: October 2018

AbstractObjectivesTo report 1‐year clinical outcomes of bioresorbable vascular scaffold (BVS) in acute coronary syndromes (ACS) population.BackgroundBVS use has rapidly extended to high‐risk patients as those presenting with ACS. To date limited data have been reported on BVS performance in ACS patients.MethodsRAI is a multicenter, prospective registry that included 1,505 patients treated with at least 1 successful BVS implantation. A subgroup analysis on ACS patients was performed and the 1‐year outcomes of this cohort compared to the remaining stable coronary artery disease (SCAD) population are reported here. Coprimary endpoints were target‐lesion revascularization (TLR) and scaffold thrombosis (ScT) at 1‐year follow‐up.ResultsFifty‐nine percent of the patients presented with ACS, of whom 36.5% with ST‐elevation myocardial infarctions. ACS patients were significantly younger, with a better cardiovascular risk profile, a lower rate of multivessel disease, chronic total occlusion or in‐stent restenosis and a lower Syntax score. Predilation and postdilation were performed in 97.4% and in 96.5% of cases, respectively. No differences were noted in terms of TIMI 3 final flow, but acute gain was greater in ACS compared to SCAD group (P < 0.001). At one‐year follow‐up no differences were found in terms of TLR (3.3% vs. 3.3%, P = 0.98), and device‐oriented composite end‐point (4.3% vs. 3.4%, P = 0.4) between ACS and SCAD groups. The rate of definite/probable ScT was numerically higher in ACS vs. stable CAD patients (1.3% vs. 0.8%, P = 0.2).ConclusionsOur data suggest that the use of BVS in ACS patients is associated with a numerically higher rate of ScT compared to SCAD population numerically higher, but without statistical significance.
Open fan sign: An ultrasound finding suggesting postpartum intrauterine forgotten gauze
Authors: Wang Liangcheng , Kuwata Tomoyuki , Horiuchi Isao , Ariga Haruko , Imai Ken , Ko Hiroyoshi , Kimura Azusa , Chikazawa Kenro , Oide Shiho , Takagi Kenjiro 
Published: October 2018

Key Clinical MessageGauze counting is regarded as the most essential way to prevent forgotten gauze inside the body during any surgery. However, incident may still occur due to artificial mistake. An open fan sign on ultrasonography may indicate a gauze left in the intrauterine cavity.
Honeycomb‐Paperboard Glass Composite Beams
Authors: Lübke Julia , Wettlaufer Marius , Kiziltoprak Nihat , Drass Michael , Schneider Jens , Knaack Ulrich 
Published: October 2018

ABSTRACTThis paper deals with a feasibility study of honeycomb‐paperboard glass composite beams for use in construction and façade construction. Based on a literature review of sandwich constructions, a basic concept for paper‐glass composite girders is presented. They are the first experimental and numerical investigations to confirm the potential for the novel combination of paper and glass as a composite material.
The CEN‐TS “Structural Glass – Design and Construction Rules” as pre‐standard for the Eurocode
Authors: Feldmann Markus , Di Biase Pietro 
Published: October 2018

ABSTRACTThe paper informs about the current European standardization work on the CEN/TC 250/SC11 “Structural Glass” with regard to glass components relevant to the building authorities. In addition to the agreed procedure on European basis, the most important issues of structure and design approaches of the future Eurocode are presented.
Comparison of LSG‐design according to German and European Standards
Authors: Siebert Geralt , Botz Martin , Kraus Michael A. 
Published: October 2018

ABSTRACTRecently the German standard for design of glass structures DIN 18008 [1] was revised; an updated version [2] was published as draft version by May 2018. On European level, the two codes EN16612 [3] and EN16613 [4] for design of “infill‐panels” have been published after long period of working on it. The work on Eurocode for Glass is not finished yet, but first ideas do exist. In this paper, the design of Laminated Safety Glass (LSG) according to German design standard DIN 18008 (2010 and 2018) and the European EN16612 with EN16613 (2017) will be compared. As German design standard does not allow using the effect of shear transfer, the application of National Technical Approvals (“allgemeine bauaufsichtliche Zulassung”) together with DIN 18008 for taking shear transfer of interlayer into consideration will be looked at. In the first part, design equations are reviewed, including different values of used material parameters, simplified formulas and safety factors. As the different approaches and assumptions do not make a comparison easy, several examples are calculated to be able to illustrate the differences showing calculation results. In addition, restrictions of different codes are explained. Finally, a link to actual research work on the field of characterizing interlayer materials is made.
Studies on glass facades morphologies
Authors: Brzezicki Marcin 
Published: October 2018

ABSTRACTThe wealth of geometrical variations of glass facades calls for a thorough study of glass facade morphology. The term ‘morphology’, which is typically associated with biological sciences, is also commonly used in urban and architectural design to describe the appearance and physical structure of the building's volume and its envelope. In many cases the morphology of the façade is closely related to its physiology, i.e. the manner in the facade works (e.g. a layered construction resulting from ventilation requirements), while in other cases, the form of the façade functions strictly as aesthetic expression. The presented brief study of façade morphology investigates the effects of two and three dimensional transformations made to a planar surface and the resulting complexity of façade variants. On the highest level the facades are grouped according to the geometrical modification of the original planar façade: (i) its spatial deformations which preserve the continuity of the surface (single or double curved continuous surfaces) or (ii) segmented iterations which break the continuity of the surface (serrated, folded, prismatic, triangulated). Two and three dimensional spatial deformations as well as iterations such as: translation, rotation, division, and multiplication produce a multitude of different solutions, which are grouped in the following table, which illustrates the possible options of façade geometry.