bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rotator Cuff Repair in Adolescent Athletes
Authors: Azzam Michael G. , Dugas Jeffrey R. , Andrews James R. , Goldstein Samuel R. , Emblom Benton A. , Cain E. Lyle 
Published: February 2018

Background: Rotator cuff tears are rare injuries in adolescents but cause significant morbidity if unrecognized. Previous literature on rotator cuff repairs in adolescents is limited to small case series, with few data to guide treatment. Hypothesis: Adolescent patients would have excellent functional outcome scores and return to the same level of sports participation after rotator cuff repair but would have some difficulty with returning to overhead sports. Study Design: Case series; Level of evidence 4. Methods: A retrospective search of the practice’s billing records identified all patients participating in at least 1 sport who underwent rotator cuff repair between 2006 and 2014 with an age <18 years at the time of surgery and a minimum follow-up of 2 years. Clinical records were evaluated for demographic information, and telephone follow-up was obtained regarding return to play, performance, other surgery and complications, a numeric pain rating scale (0-10) for current shoulder pain, American Shoulder and Elbow Surgeons (ASES) Shoulder Assessment Form, and the Western Ontario Rotator Cuff Index. Results: Thirty-two consecutive adolescent athletes (28 boys and 4 girls) with a mean age of 16.1 years (range, 13.2-17.9 years) met inclusion criteria. Twenty-nine patients (91%) had a traumatic event, and 27 of these patients (93%) had no symptoms before the trauma. The most common single tendon injury was to the supraspinatus (21 patients, 66%), of which 2 were complete tendon tears, 1 was a bony avulsion of the tendon, and 18 were high-grade partial tears. Fourteen patients (56%) underwent single-row repair of their rotator cuff tear, and 11 (44%) underwent double-row repair. All subscapularis injuries were repaired in open fashion, while all other tears were repaired arthroscopically. Twenty-seven patients (84%) completed the outcome questionnaires at a mean 6.2 years after surgery (range, 2-10 years). The mean ASES score was 93 (range, 65-100; SD = 9); mean Western Ontario Rotator Cuff Index, 89% (range, 60%-100%; SD = 13%); and mean numeric pain rating, 0.3 (range, 0-3; SD = 0.8). Overall, 25 patients (93%) returned to the same level of play or higher. Among overhead athletes, 13 (93%) were able to return to the same level of play, but 8 (57%) were forced to change positions. There were no surgical complications, but 2 patients did undergo a subsequent operation. Conclusion: Surgical repair of high-grade partial-thickness and complete rotator cuff tears yielded successful outcomes among adolescents, with excellent functional outcomes at midterm follow-up. However, overhead athletes may have difficulty playing the same position after surgery.
HCV viraemia in anti-HCV-negative haemodialysis patients: Do we need HCV RNA detection test?
Authors: Papadopoulos Nikolaos , Griveas Ioannis , Sveroni Eirini , Argiana Vasiliki , Kalliaropoulos Antonios , Martinez-Gonzalez Beatriz , Deutsch Melanie 
Published: February 2018

Background: Hepatitis C virus (HCV) infection is still common among dialysis patients, but the natural history of HCV in this group is not completely understood. The KDIGO HCV guidelines of 2009 recommend that chronic haemodialysis patients be screened for HCV antibody upon admission to the dialysis clinic and every 6 months thereafter if susceptible to HCV infection. However, previous studies have shown the presence of HCV viraemia in anti-HCV-negative haemodialysis patients as up to 22%. Objectives: To evaluate the presence of HCV viraemia, using HCV RNA detection, among anti-HCV-negative haemodialysis patients from a tertiary dialysis unit in Athens. Methods: We enrolled 41 anti-HCV-negative haemodialysis patients diagnosed with third-generation enzyme immunoassay. HCV viraemia was evaluated using a sensitive (cut-off: 12 IU/mL) reverse transcriptase polymerase chain reaction (COBAS AmpliPrep/TaqMan system) for HCV RNA. Results: None of the 41 anti-HCV-negative haemodialysis patients were shown to be viraemic. Conclusions: Routine HCV RNA testing appears not to be necessary in anti-HCV-negative haemodialysis patients.
The Debate in Urban Anthropology and the Development of the Empirical Investigation of Governance
Authors: De Vivo Paola 
Published: February 2018

AbstractThe complexity of our ‘object’ of study, leading to the question ‘what is really the city?’ requires the use of different levels of analyses. At the same time, a way must be found to develop an explanatory model that brings together the knowledge thus produced. The study of governance in the city is necessarily part of any research aimed at investigating empirically the processes regulating the social life. The key implication is to address its impact; a task made particularly complex by the often difficult relationship between the implementation of governance and the interaction with a diversity of societal actors, for the ongoing dialectic between the formal and the informal in urban life. We often find that this dialectic produces ambiguity, unexpected results, gaps between planned objectives, and competition instead of cooperation among actors, pointing to the weakness of the rationalistic model of public action. Perhaps the most important lesson that we have learnt about government and governance is that the delusion that we feel when trying to understand urban policies results from our incapacity fully to grasp the complexity of human life.
Italian Elite Groups at Work: A View from the Urban Grassroots
Authors: Pardo Italo 
Published: February 2018

AbstractWestern élite groups’ moralities and actions can and should be studied empirically. Contrary to belief held in the 1980s in mainstream social anthropology that fieldwork in the classic anthropological fashion could not be done among the western élite, the findings of long-term research in this field have yielded key ethnographic insights leading to academic and public debate. In this article I draw on ethnographic research on legitimacy, power, and governance among key Neapolitan élite groups to offer reflections on a style of governance that has at once engendered and thrived on the blurring of the dividing line between what is legitimate and what is not legitimate in public life. The discussion focuses on powerful, tightly networked groups that, inspired by an elitist philosophy of power, have been hard at work to gain and maintain power, while losing trust and authority. The analysis builds towards an understanding of their implosion and of the corresponding erosion of the relationship between citizenship and governance.
Ethnicity in the City: Tatar Urban Youth Culture in Kazan, Tatarstan
Authors: Friedli Andrea 
Published: February 2018

AbstractIn this article, the city and the urban space shall be understood as a political platform, where identities and powers are bargained, and as a screen on which they are projected. In this context, I will reflect on the strategies of identity management ‘from below’ employed by Tatar young people in Kazan and on their attempt to build a ‘Tatar urban youth culture’. These identity strategies are mainly oriented against the ‘Russian other’, a decadent consumerist West and an ignorant rural Tatar culture and their main issue is the ‘repossessing’ of Kazan and the Tatarisation of the city. Such strategies namely include the use of the Tatar language in predominantly Russophone public spheres, the introduction of Tatar folkloristic elements in music and fashion as well as the appeal to a (lost) Tatar urban culture associated with an enlightened approach to Islam and to the pre-revolutionary Tatar intelligentsia. Tatar youth scenes thus use ethnicity as a resource in the linguistic, religious, historic and cultural (re)appropriation of the urban space, which in turn has to be understood as a symbolic political act in a specific historical as well as ‘glocal’ context. Thus, this article can be seen as a contribution to a critical approach towards cosmopolitanism introducing alternative concepts to reflect relationships, norms and values in urban life.
Do Investments in Mental Health Systems Result in Greater Use of Mental Health Services? National Trends in Mental Health Service Use (MHSU) in the Canadian Military and Comparable Canadian Civilians, 2002-2013
Authors: Fikretoglu Deniz , Liu Aihua , Zamorski Mark Allen , Rusu Corneliu , Jetly Rakesh 
Published: February 2018

Background: Mental disorders constitute a significant public health problem worldwide. Ensuring that those who need mental health services access them in an appropriate and timely manner is thus an important public health priority. We used data from 4 cross-sectional, nationally representative population health surveys that employed nearly identical methods to compare MHSU trends in the Canadian military versus comparable civilians. Method: The surveys were all conducted by Statistics Canada, approximately a decade apart (Military-2002, Military-2013, Civilian-2002, and Civilian-2012). The sample size for the pooled data across the surveys was 35,984. Comparisons across the 4 surveys were adjusted for differences in need in the 2 populations at the 2 time points. Results: Our findings suggested that first, in the Canadian military, there was a clear and consistent pattern of improvement (i.e., increase) in MHSU over the past decade across a variety of provider types. The magnitudes of the changes were large, representing an absolute increase of 7.15% in those seeking any professional care, corresponding to an 84% relative increase. Second, in comparable Canadian civilians, MHSU remained either unchanged or increased only slightly. Third, the increases in MHSU over time were consistently greater in the military than in the comparable civilian sample. Conclusions: Our findings point to advantages with respect to MHSU of the military mental health system over the civilian system in Canada; these advantages have widened substantially over time. These findings speak strongly to the potential impact of analogous changes in other health systems, both military and civilian.
Acceptability of non-speculum clinician sampling for cervical screening in older women: A qualitative study
Authors: Freeman Madeleine , Waller Jo , Sasieni Peter , Lim Anita WW , Marlow Laura AV 
Published: February 2018

Objectives One reason that women over age 50 report avoiding cervical screening is increased discomfort postmenopause. This study aimed to explore the acceptability of human papillomavirus testing on clinician-collected vaginal samples without a speculum (‘non-speculum’) for cervical screening among older women. Methods Thirty-eight women in England aged 50–64 with a range of cervical screening experience (‘up-to-date’ n = 17, ‘overdue screening’ n = 18, ‘never screened’ n = 3) were identified via a recruitment agency. Women participated in focus groups or interviews about the potential for using clinician-collected samples without a speculum. Discussions were analysed using Framework Analysis. Results The two main themes identified were women’s perceptions of the speculum and attitudes towards non-speculum screening. Many women reported negative experiences with the speculum, including increased pain after the menopause. Women generally had positive attitudes towards non-speculum clinician sampling and felt it would be a less intrusive option, but expressed concern that it could be less accurate than screening with a speculum. Women who were ‘up-to-date’ preferred conventional screening, while overdue and never screened women welcomed the option to be screened without a speculum. Conclusions Human papillomavirus testing on non-speculum clinician-collected vaginal samples could be an acceptable alternative cervical screening method for older women. Offering this approach could increase screening uptake in older women who find conventional cervical screening to be less acceptable with ageing or the menopause.
Telepractice delivery of family-centred early intervention for children who are deaf or hard of hearing: A scoping review
Authors: McCarthy Melissa , Leigh Greg , Arthur-Kelly Michael 
Published: February 2018

Introduction The use of telepractice, a method of delivering services through telecommunications technologies that provides two-way, synchronous audio and video signals in real-time, is becoming increasingly commonplace in early childhood education and intervention for children who are deaf or hard of hearing. Although the use of telepractice has been validated in the health sector as a viable and effective alternative to in-person service provision, evidence to support its use in the delivery of family-centred early intervention is still emerging. The purpose of this scoping review was to describe the current use of telepractice in the delivery of family-centred early childhood intervention for children who are deaf or hard of hearing, and their families. Method The review followed the framework outlined by the Joanna Briggs Institute (2015), including an iterative three-step search strategy. Specific inclusion criteria and data extraction fields were outlined in advance. Results A total of 23 peer-reviewed publications were included in the review. Most publications (70%) provided anecdotal evidence of the challenges and benefits associated with telepractice. The remaining publications (30%) reported on research studies evaluating the effectiveness of early intervention delivered through telepractice. Of the 23 included papers, 18 viewed the use of telepractice positively while the remaining 5 reported mixed conclusions and the need for more data. Discussion Current evidence in the literature indicates that telepractice can be an effective model for delivering family-centred early intervention for children who are deaf or hard of hearing. However, more research is needed to substantiate the use of telepractice as a viable alternative to traditional in-person services, rather than being seen as supplemental to such services.
A generalized additive model approach to time-to-event analysis
Authors: Bender Andreas , Groll Andreas , Scheipl Fabian 
Published: February 2018

Abstract: This tutorial article demonstrates how time-to-event data can be modelled in a very flexible way by taking advantage of advanced inference methods that have recently been developed for generalized additive mixed models. In particular, we describe the necessary pre-processing steps for transforming such data into a suitable format and show how a variety of effects, including a smooth nonlinear baseline hazard, and potentially nonlinear and nonlinearly time-varying effects, can be estimated and interpreted. We also present useful graphical tools for model evaluation and interpretation of the estimated effects. Throughout, we demonstrate this approach using various application examples. The article is accompanied by a new R -package called pammtools implementing all of the tools described here.
Student participation at Helping Hand Aged Care: taking clinical placement to the next level
Authors: Loffler Helen , Barnett Kate , Corlis Megan , Howard Sara , Van Emden Jan 
Published: February 2018

Background The Student Education and Participation Program that has evolved at Helping Hand Aged Care over the past decade is based on ongoing research and evaluation, and a highly innovative example of the teaching nursing home model has emerged. Methods Drawing on that body of work and findings from the national evaluation of Australia’s TRACS (Teaching and Research Aged Care Services) programme (2012–2015) an analysis of the model is presented. Results and conclusions Lessons learned about the challenges faced, enabling factors, the benefits generated and outcomes achieved are presented.
Comprehensive Examination of the Athlete’s Shoulder
Authors: Cotter Eric J. , Hannon Charles P. , Christian David , Frank Rachel M. , Bach Bernard R. 
Published: February 2018

Context: Shoulder pain and dysfunction are common, with patients presenting complaints to both primary and orthopaedic physicians. History and physical examination remain essential to creating a differential diagnosis, even as noninvasive imaging has improved. Evidence Acquisition: Literature was obtained through keyword searches based on the pathology in question (eg, rotator cuff) and the keywords physical examination using PubMed from January 1, 1980, through September 20, 2017. Additional evidence was obtained through screening references from articles identified through the PubMed searches. Study Design: Clinical review. Level of Evidence: Level 3. Results: A total of 7817 articles were screened for relevance. Several physical examination maneuvers have been described for each specific pathology. The Neer sign has a 75% sensitivity for subacromial impingement (SAI), while the Hawkins-Kennedy test has an 80% sensitivity. The painful arc test has an 80% specificity for SAI. The apprehension test has a hazard ratio of 2.96 for anterior shoulder instability. The Jobe test has a sensitivity of 52.6% and a specificity of 82.4% for full-thickness supraspinatus tears, confirmed on arthroscopy. The lag sign is highly sensitive and specific for combined full-thickness supraspinatus and infraspinatus tears at 97% and 93%, respectively. The Speed test has a sensitivity of 54% and specificity of 81% for biceps pathology. The anterior slide test and O’Brien active compression test have been described for superior labrum anterior posterior tears with inconsistent reliability. The cross-body adduction test has a sensitivity of 77% and a specificity of 79% for acromioclavicular joint pathology. Conclusion: Several physical examination maneuvers can isolate specific pathology of the shoulder, with widely ranging sensitivity and specificity.
Lexical metaphor as affiliative bond in newspaper editorials: a systemic functional linguistics perspective
Authors: Liu Feifei 
Published: February 2018

AbstractFrom the perspective of systemic functional linguistics (SFL), lexical metaphors are recognized as a resource for enacting interpersonal meaning in discourse. Within theappraisalframework, they constitute a means for ‘provoking’ an attitudinal interpretation. While the interpersonal function of lexical metaphors is well recognized in SFL, there have been relatively few studies that focus specifically on their deployment in the construction of recurring rhetorical strategies in discourse. This is explored in this study in the context of media editorials. It is found that there are patterns in the choices of lexical metaphor, in the values they provoke and the experiential entities these values couple with. The reinforcement of these evaluative couplings in the flow of text functions to promote values similar to the provoked ones. The analyses also show that lexical metaphors propose bonds of affiliation to a putative readership and therefore foster the readers of the newspaper.
An evolutionarily conserved NIMA-related kinase directs rhizoid tip growth in the basal land plant Marchantia polymorpha
Authors: Otani Kento , Ishizaki Kimitsune , Nishihama Ryuichi , Takatani Shogo , Kohchi Takayuki , Takahashi Taku , Motose Hiroyasu 
Published: February 2018

ABSTRACT
Tip growth is driven by turgor pressure and mediated by the polarized accumulation of cellular materials. How a single polarized growth site is established and maintained is unclear. Here, we analyzed the function of NIMA-related protein kinase 1 (MpNEK1) in the liverwort Marchantia polymorpha. In the wild type, rhizoid cells differentiate from the ventral epidermis and elongate through tip growth to form hair-like protrusions. In Mpnek1 knockout mutants, rhizoids underwent frequent changes in growth direction, resulting in a twisted and/or spiral morphology. The functional MpNEK1-Citrine protein fusion localized to microtubule foci in the apical growing region of rhizoids. Mpnek1 knockouts exhibited increases in both microtubule density and bundling in the apical dome of rhizoids. Treatment with the microtubule-stabilizing drug taxol phenocopied the Mpnek1 knockout. These results suggest that MpNEK1 directs tip growth in rhizoids through microtubule organization. Furthermore, MpNEK1 expression rescued ectopic outgrowth of epidermal cells in the Arabidopsis thaliana nek6 mutant, strongly supporting an evolutionarily conserved NEK-dependent mechanism of directional growth. It is possible that such a mechanism contributed to the evolution of the early rooting system in land plants.
Variant cell cycles regulated by Notch signaling control cell size and ensure a functional blood-brain barrier
Authors: Von Stetina Jessica R. , Frawley Laura E. , Unhavaithaya Yingdee , Orr-Weaver Terry L. 
Published: February 2018

ABSTRACTRegulation of cell size is crucial in development. In plants and animals two cell cycle variants are employed to generate large cells by increased ploidy: the endocycle and endomitosis. The rationale behind the choice of which of these cycles is implemented is unknown. We show that in the Drosophila nervous system the subperineurial glia (SPG) are unique in using both the endocycle and endomitosis to grow. In the brain, the majority of SPG initially endocycle, then switch to endomitosis during larval development. The Notch signaling pathway and the String Cdc25 phosphatase are crucial for the endocycle versus endomitosis choice, providing the means experimentally to change cells from one to the other. This revealed fundamental insights into the control of cell size and the properties of endomitotic cells. Endomitotic cells attain a higher ploidy and larger size than endocycling cells, and endomitotic SPG are necessary for the blood-brain barrier. Decreased Notch signaling promotes endomitosis even in the ventral nerve cord SPG that normally are mononucleate, but not in the endocycling salivary gland cells, revealing tissue-specific cell cycle responses.
A molecular framework controlling style morphology in Brassicaceae
Authors: Simonini Sara , Stephenson Pauline , Østergaard Lars 
Published: February 2018

ABSTRACT
Organ formation in multicellular organisms depends on the coordinated activities of regulatory components that integrate developmental and hormonal cues to control gene expression and mediate cell-type specification. For example, development of the Arabidopsis gynoecium is tightly controlled by distribution and synthesis of the plant hormone auxin. The functions of several transcription factors (TFs) have been linked with auxin dynamics during gynoecium development; yet how their activities are coordinated is not known. Here, we show that five such TFs function together to ensure polarity establishment at the gynoecium apex. The auxin response factor ETTIN (ARF3; herein, ETT) is a central component of this framework. Interaction of ETT with TF partners is sensitive to the presence of auxin and our results suggest that ETT forms part of a repressive gene-regulatory complex. We show that this function is conserved between members of the Brassicaceae family and that variation in an ETT subdomain affects interaction strengths and gynoecium morphology. These results suggest that variation in affinities between conserved TFs can lead to morphological differences and thus contribute to the evolution of diverse organ shapes.