bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-adaptation of e-learning software based on observing the information environment
Authors: Bershadskiy A. M. , Bozhday A. S. , Gudkov A. A. , Evseeva Yu. I. 
Published: July 2019

Purpose of the research. The purpose of the study is to develop a new universal method of self-adaptation of applied software systems used in the field of e-learning (E-Learning). Self-adaptation refers to the ability of a software application to change its own structure and behavior depending on external circumstances, which include, for example, the trainee’s personal characteristics, which is especially important for systems used in education. Such self-adaptive behavior should be sufficiently flexible and not be reduced to the choice of one of the many behavioral options predetermined by the developer (such behaviors should also be generated throughout the system’s life cycle). Materials and methods. The method being developed uses an array of user reviews about software as initial data, for the subsequent processing of which the methods of latent-semantic and distributive-statistical analysis are used. To represent the generalized self-adaptive structure of the system, models of characteristics are used. The configuration of the model of characteristics is a separate state of the self-adaptive system, they are generated automatically during the program’s life cycle as follows: based on an array of user reviews, a semantic network of basic concepts characterizing the program is formed, which is further compared with the original model of characteristics and personal characteristics of the user who left review. Determining a user’s personal characteristics can be done in a variety of ways (for example, using psychological testing or by analyzing learning outcomes). Results. The main results of the study are: 1) universal principles of building a self-adaptive e-learning system 2) a way of presenting the self-adaptive structure of a software system in the form of a characteristics model relevant to a wide range of software 3) a new universal method of self-adapting applied software used in E-Learning the main differences of which from the existing ones are, firstly, in using the opinions of the users of the system themselves to adjust with self-adaptive behavior, secondly, in the possibility of generating new states of the system throughout the entire period of its operation. Conclusion. The developed theoretical apparatus makes it possible to significantly individualize the learning process, take into account the opinions and inclinations of the students themselves, reduce the role of the pedagogical worker in the assessment of knowledge and skills. In addition to problems of a purely educational nature, the application of the method also allows you to successfully resolve technical issues related to the development of software in general. Such problems include, for example, the problem of software complexity, when a program that shows good results in some operating conditions shows insufficient performance in others. Also a serious task, which the proposed method can cope with, is the task of increasing the life cycle of a software system.
Synthesis and In Silico Molecular Docking Studies on Substituted Piperic Acid Derivatives as Inhibitors of Bacterial DNA Gyrase
Authors: Chopra Bhawna , Dhingra Ashwani K. , Prasad Deo N. , Bhardwaj Sakshi , Dubey Sonal 
Published: July 2019

Background:Piperine or piperic acid was isolated from fruits of Piper nigrum and had been reported as pharmacological valuable bioactive constituents. Keeping in view, a series of piperic acid-based N heterocyclic’s derivatives were synthesized and evaluated for antibacterial activity. All these prepared ligands were docked to study the molecular interactions and binding affinities against the protein PDB ID: 5 CDP.Objective:To meet the real need of newer antibacterials, we designed and synthesized scaffolds with good antibacterial activity. The obtained antibacterials have been validated in terms of ligand-protein interaction and thus prove to build up as good drug candidates.Methods:Antibacterial activity of the compounds were carried out against bacterial strains; three Grampositive and three Gram-negative bacterial strains using agar well diffusion method. In silico molecular docking studies were carried out using Glide (grid-based ligand docking) program incorporated in the Schrödinger molecular modeling package by Maestro 11.0.Results:Compounds BC 28, BC 32, and BC 33 exhibits antibacterial activity along with Glide docking score of -8.580, -9.753 kcal/mol, and -8.813 kcal/mol, respectively. Docking studies explained hydrogen bonding, pi-pi, and hydrophobic interactions with amino acid residues which explain the binding affinity of the most docked ligand with protein.Conclusion:In the present study, substituted piperic acid was synthesized and evaluated as antibacterial compared with standard drug ciprofloxacin and results interpret that having nitrogen as heteroatom in the heterocyclic nucleus found to be more potent than the standard drug ciprofloxacin. On comparing, substitution with electron-donating groups generates excellent antibacterial potential against the bacterial strains. It was also proved that having substitution with electron-donating groups on meta and para position with triazoline ring system exhibits greater potential while compounds which have a meta- electron-donating substituent showed lesser activity with thiazole nucleus. In addition, structure-based activities of the prepared analogs were discussed under Structure-Activity Relationship (SAR) section.
Influence of Betaine- and Choline-based Eutectic Solvents on Lipase Activity
Authors: Ribeiro Bernardo Dias , de Carvalho Iff Lucas , Coelho Maria Alice Zarur , Marrucho Isabel M. 
Published: July 2019

Background:
Eutectic solvents are a mixture of two compounds which possess a lower
melting temperature than the parent compounds, using quaternary ammonium salts, such as choline
chloride and betaine hydrochloride and organic acids, polyols and amides as hydrogen bond donors.
These solvents can be an alternative as non-aqueous media for enzymatic reactions, mainly using lipases.

Objective:
The objective of this work is to evaluate enzymatic activity and stability of commercial lipases,
immobilized or at free form (Thermomyces lanuginosus: Lipozyme TL IM, iTL and Lipolase
100 L, fTL; Candida antarctica: Novozym 435, iCALB; Novozym 735, iCALA and Novozym CALB
L, fCALB); and a phospholipase (Lecitase Ultra), in the presence of eutectic solvents (choline chloride
ChCl:urea, ChCl:glycerol, betaine hydrochloride (BeHCl):urea and BeHCl: glycerol.

Methods:
Initially, lipases were maintained for 2 hours in solutions of choline and betaine-based
eutectic solvents (1 to 20% m/m) at 25ºC compared with water for relative enzymatic activity. Using
the solvent that best promoted lipase activity, some parameters were evaluated such as the molar ratio
between quaternary ammonium salts and urea, stocking temperature and kinetics.

Results and Conclusion:
These eutectic solvents enable, mainly with immobilized lipases, 25 to 125
times more activity than water at 25ºC and 2h, and even after 24h, lipase iTLL was still 40 times more
active in the presence of ChCl:Urea 1:3. Lipase iCALB showed great thermostability 47 times higher
at 55ºC, almost double relative activity at 25ºC in the presence of BetHCl:Urea 1:4.
TINGKAT PENGETAHUAN PELATIH BOLA VOLI TENTANG PROGRAM LATIHAN MENTAL DI KABUPATEN SLEMAN YOGYAKARTA
Authors: Syamsuryadin Syamsuryadin , Wahyuniati Ch. Fajar Sri 
Published: July 2019

Penelitian ini bertujuan untuk mengidentifikasi tingkat pengetahuan pelatih bola voli tentang program latihan mental untuk atlet. Penelitian ini merupakan penelitian deskriptif dengan metode survey. Subyek penelitian ini adalah seluruh pelatih bola voli di Kabupaten Sleman yang sesuai kriteria sebanyak 16 orang. Hasil penelitian menunjukkan bahwa tingkat pengetahuan pelatih bola voli di Kabupaten Sleman tentang program latihan mental adalah sebagai berikut : berkategori “sangat kurang” sebesar 6,25%, kategori “kurang” sebesar 18,75%, kategori “cukup” sebesar 43,75%, kategori “baik” sebesar 18,75% dan kategori “sangat baik” sebesar 12,5 %. Nilai rata-rata yang dimiliki adalah 37,69 yang menunjukkan bahwa mayoritas pengetahuan pelatih bola voli tentang program latihan mental di Kabupaten Sleman berkategori sedang. Kata kunci : program latihan mental, pelatih bola voli, tingkat pengetahuan.
TATALAKSANA HENTI JANTUNG DI LAPANGAN PERMAINAN
Authors: Rizki Putra , Cahyani Nani 
Published: July 2019

Cardiac arrest is the most common cause of sudden death in athletes on the field of play. There are reports of cardiac arrest in athletes 1: 4000 to 1: 8000.Cardiac and non-cardiac causes have been implicated as a causes of death in the field of play. Pre-Participation Evaluation (PPE) has been recommended for primary prevention of cardiac arrest in athletes due to cardiac problems. Prevention of sudden cardiac death on the field of the play should be done by immediate, precise and correct treatment. Immediate, precise and correct treatment can be provided if medical management is well performed before and during the event. Medical management in sudden cardiac arrest treatment on the field of play consists of early preparation, emergency action plan, preparing equipment, personnel, training, communication, transportation and final preparation. An ideal treatment includes elements of the chain of survival from sudden cardiac arrest.ABSTRAK Henti jantung adalah penyebab kematian mendadak terbanyak pada atlet di lapangan permainan. Terdapat laporan kejadian henti jantung pada atlet 1:4000 sampai 1:8000. Penyebab kematian akibat henti jantung di lapangan permainan bisa karena masalah jantung dan masalah selain jantung. Untuk pencegahan primer terjadinya henti jantung pada atlet di lapangan permainan yang disebabkan masalah jantung direkomendasikan melakukan Pre-Participation Evaluation (PPE). Untuk pencegahan terjadinya kematian akibat henti jantung di lapangan permainan harus dilakukan tatalaksana yang cepat, tepat dan benar. Tatalaksana yang cepat, tepat dan benar dapat diberikan jika manajemen medis dilakukan dengan baik sebelum dan saat event berlangsung. Manajemen medis dalam tatalaksana henti jantung di lapangan permainan terdiri dari persiapan awal, rencana kegawatdaruratan, mempersiapkan peralatan, personel, pelatihan, komunikasi, transportasi dan persiapan akhir. Tatalaksana di lapangan permainan yang ideal mencakup elemen rantai keselamatan pada henti jantung. Kata kunci: henti jantung, lapangan permainan, manajemen medis, penanganan SCA
Aproximación para establecer y evaluar la relevancia clínica de las interacciones medicamentosas en el tratamiento de pacientes infectados con virus de hepatitis C, revisión estructurada (actualización 2015 – 2017)
Authors: Pino Marín Daniel Esteban , Amariles Pedro , Peláez Alvárez Jaime Alberto , Alvárez Osorio Gloria Priscilla , González Ceballos Juliana 
Published: July 2019

Objetivo: establecer y evaluar la relevancia clínica de las interacciones medicamentosas en el tratamiento de pacientes con hepatitis C.
Método: se realizó una búsqueda en PubMed/MedLine de artículos publicados en inglés y en español, desde el 1 de enero de 2015 hasta el 30 de marzo de 2017, utilizando los términos Mesh: Hepatitis C AND drug interactions OR herb-drug interactions OR food-drug interactions, de estudios realizados en humanos. La relevancia clínica de las interacciones medicamentosas se estableció y evaluó con base en la probabilidad de ocurrencia y la gravedad de la interacción.
Resultados: se identificaron 184 artículos, de los cuales 92 se seleccionaron por el título y resumen para revisión completa, a 2 de ellos no fue posible acceder al texto completo. De estos, 57 aportaban interacciones, lo que permitió identificar 155 parejas de interacciones medicamentosas, de las cuales 154 (99,4 %) fueron farmacocinéticas y 1 (0,6 %) farmacodinámica. Por su parte, de las 155 parejas, 34 (21,9 %) se valoraron de nivel 1; 73 (47,1 %) de nivel 2; 48 (31,0 %) de nivel 3; y 0 (0,0 %) de nivel 4. Además, se identificaron 29 parejas agrupadas como interacciones con evidencia de ausencia de relevancia clínica.
Conclusiones: más de 99 % de las interacciones medicamentosas de relevancia clínica son farmacocinéticas, asociadas con cambios en el metabolismo y el transporte de fármacos; el simeprevir y la terapia 3D (Paritaprevir/Ritonavir+ Ombitasvir+Dasabuvir) fueron los medicamentos con mayor número de interacciones.
A comunicação dos riscos na logística reversa das embalagens de agrotóxicos no Brasil
Authors: Leal Daniela de Ulyssea , Lopes Ivonete da Silva 
Published: July 2019

Este artigo investiga como o Instituto Nacional de Processamento de Embalagens Vazias, responsável pelo programa de recolhimento de embalagens de agrotóxicos, comunica os riscos que envolvem as práticas com produtos agroquímicos através do conteúdo do seu site. Desde 2002, a responsabilidade compartilhada nesta cadeia de logística reversa é obrigatória por lei. Com a ajuda do softwear Iramuteq foi realizada uma análise de conteúdo baseada na frequência das palavras, resultando numa estrutura de nuvem, e de similitude. Através destas análises pode-se apreender que o instituto lança mão de eufemismo para comunicar tais riscos, inclusive substituindo o termo agrotóxico por defensivo agrícola.
Palavras-chave: Comunicação de Risco. Agrotóxico. Logística Reversa.
Influence of Zinc Sulphate on the Probiotic Properties of Lactobacillus plantarum CCM 7102
Authors: Mudroňová D. , Gancarčíková S. , Nemcová R. 
Published: July 2019

Abstract
The effects of zinc sulphate on selected properties of L. plantarum CCM 7102 were tested in vitro. The resistance of lactobacilli to higher concentrations of ZnSO4 (up to 5000 mg Zn2+.l−1) in growth media was strain-dependent. Further studies were carried out on the most resistant strain of L. plantarum CCM 7102. While the addition of low concentrations of zinc sulphate into the growth media (< 100 mg Zn2+.l−1) did not influence the properties of L. plantarum CCM 7102, the concentrations of 100—500 mg Zn2+.l−1 stimulated: the growth rate, production of lactic acid, adhesion to porcine enterocytes and the inhibition of pathogens E. coli O8:K88+ent+, S. enterica and S. Typhimurium. Conversely, however, high concentrations > 500 mg Zn2+.l−1 inhibited these properties. The addition of zinc (250 mg Zn2+.l−1) did not affect the resistance to antimicrobials, low pH, and the resistance to bile salt was affected only weakly. Zinc-resistant probiotic Lactobacillus strains are suitable for use in feedstuffs with a higher content of zinc designed for the prevention of post weaning diarrhoea in pigs.
Effects of Slackline Training on Acceleration, Agility, Jump Performance and Postural Control in Youth Soccer Players
Authors: Fernández-Rio Javier , Santos Luis , Fernández-García Benjamín , Robles Roberto , Casquero Iván , Paredes Raúl 
Published: July 2019

Abstract
The goal of this study was to assess the effects of a supervised slackline training program in a group of soccer players. Thirty-four male division I under-19 players (16.64 ± 0.81 years) agreed to participate in the study. They were randomly divided into an experimental group (EG) and a control group (CG). The first group (EG) followed a 6-week supervised slackline training program (3 sessions/week; 5-9 min/session), while the CG performed only regular soccer training. Several variables were assessed in all participants: acceleration (20-m sprint test), agility (90º turns test), jump performance (squat jump, countermovement jump), and postural control (Center of Pressure ( CoP) testing: length, area, speed, Xmean, Ymean, Xspeed, Yspeed, Xdeviation, Ydeviation). Ratings of perceived exertion and local muscle ratings of perceived exertions were also recorded after each slackline training session. At post-tests, there was a significant increase only in the EG in acceleration, agility, squat jump and countermovement jump performance, as well as several CoP variables: area in the bipedal support on a firm surface, and length, area and speed in the left leg on a firm surface. The program was rated as “somewhat hard” by the players, while quadriceps, gastrocnemius and tibialis anterior were the most exerted muscles while slacklining. In conclusion, slackline training can be an effective training tool for young, high-level soccer players.
Experimental and Numerical Investigations of Pipeline with Resonator
Authors: Pałczyński Tomasz , Kantyka K. 
Published: July 2019

Abstract
This article presents the current state of the art regarding the use resonators in straight pipes. There is considerable need to control and reduce pressure pulsation in pipelines supplied with pulsating flows. The use of a Helmholz resonator introduces an additional degree of freedom to the analysed dynamic system. Building on previous experimental investigations by the authors, which identified the nonlinear properties of straight pipes supplied with pulsating flows, this study describes an experimental test rig, measurement methods and mechanical analogies for one (1DOF) and two (2DOF) degrees of freedom. The results are presented in the form of a 3D map of amplitude-frequency characteristics, as a function of the resonator volume determined by piston height. The dynamic properties of the described system are presented as amplitude-phase characteristics, based on a comparison of the numerical and experimental results.
Theoretical Investigation on Growth Kinetics and Thermodynamic Properties of Pyridine-2-Carboxylic Acid Crystals
Authors: Manopradha N. , Rama S. , Gowri S. , Kirubavathi K. , Selvaraju K. 
Published: July 2019

Abstract
This work illustrates the significance of kinetic parameters of nucleation and thermal decomposition for Pyridine-2-carboxylic acid crystals. In the interest of maximizing the growth condition for the production of single crystals, nucleation parameters such as interfacial energy (σ), volume free energy (ΔGv
), critical energy barrier for nucleation (ΔG
*), radius of the critical nucleus (r*) and nucleation rate (J) were determined from the classical nucleation theory of solubility-enthalpy relation. The optimized geometry of the compound was computed from the DFT-B3LYP gradient calculations employing 6-31G(d,p) basis set and its vibrational frequencies were evaluated. Based on the vibrational analysis, the thermodynamic parameters were obtained and the correlative equations between these thermodynamic properties and variation in temperatures were also reported.
Investigation of mechanical behavior of friction stir welded joints of AA6063 with AA5083 aluminum alloys
Authors: Dharani Kumar S. , Sendhil Kumar S. 
Published: July 2019

Abstract
Aluminum alloy finds its applications in various sectors of engineering. This paper discusses the investigation of mechanical characteristics of butt weld joints of aluminum alloy AA6063 along with AA5083. An experiment was conducted for different tool rotational speeds of 600 rpm, 800 rpm and 1000 rpm. Specifications of friction stir welding machine were 4 kN axial load and welding speed of 40 mm/min. Friction stir welded (FSW) joints of higher tensile strength, lower flexural strength and lower impact strength with maximum hardness, for the work piece fabricated at 1000 rpm using a high speed steel tool with a cylindrical profile was observed. Better understanding of the effect of tool rotational speed and mechanical properties was illustrated through the experimental result.
Studying of movement kinematics of dynamically active sieve
Authors: Popolov Dmitry , Shved Sergey , Zaselskiy Igor , Pelykh Igor 
Published: July 2019

Abstract
The article presents the movement kinematics of the modular bar element of a dynamically active polymer sieve of a vibrating screen. On the basis of analytical methods, the mathematical model was obtained, which makes it possible to determine the law and trajectory of the modular bar element movement depending on its geometric characteristics, physico-mechanical properties of the polymer material, the regime and technological parameters of the vibrating screen. The results of this research show that in the working frequency range of the vibrating screen grate, modular bar element of the dynamically active sieve moves along the trajectories, the envelope of which is represented by Cassini’s ovals, which along with the generation of the amplitude component in the horizontal and vertical directions allows one to obtain the selfcleaning effect of the sowing surface.
Shear buckling of steel foam sandwich panel resting on Pasternak foundation
Authors: Nazarimofrad Ebrahim , Barang Mehdi 
Published: July 2019

Abstract
The objective of this paper is to assess the inplane shear buckling of a steel foam sandwich panel that relies on elastic Pasternak foundation. The panel is a combination of solid steel face sheets and foamed steel cores. Foamed steel, that is steel with internal voids, provides enhanced bending rigidity and energy dissipation, and also, the potential to reduce local buckling. The Classic plate theory is employed where their governing equations are solved by the Rayleigh–Ritz method. Uniformly distributed in-plane shear loads are applied to the two opposite edges of the panel and all the four edges of the panel are simply supported. Finally, the effects of the panel parameters, such as the existence of a Pasternak foundation, aspect ratios, and central fraction of the steel foam core, are presented. The results showed that the optimum central fraction of the steel foam core would be 65%, so that the maximum critical shear buckling load has taken place.
A Detailed Study of Row-Trenched Holes at the Combustor Exit on Film-Cooling Effectiveness
Authors: Kianpour Ehsan , Sidik Nor Azwadi Che 
Published: July 2019

Abstract
To analyse the effects of cylindrical- and row-trenched cooling holes with an alignment angle of 90 degrees on the film-cooling effectiveness near the combustor end wall surface at a blowing ratio of 3.18, the current research was done. This research included a 3D representation of a Pratt and Whitney gas turbine engine, which was simulated and analysed with a commercial finite volume package FLUENT 6.2.26. The analysis was done with Reynolds-averaged Navier–Stokes turbulence model on internal cooling passages. This combustor simulator was combined with the interaction of two rows of dilution jets, which were staggered in the streamwise direction and aligned in the spanwise direction. In comparison with the baseline case of cooling holes, using row-trenched hole near the end wall surface increased the film-cooling effectiveness 44% in average.
Investigation of the effect of thermal stress on the interface damage of hybrid biocomposite materials
Authors: Sadat Salima , Mokaddem Allel , Doumi Bendouma , Berber Mohamed , Boutaous Ahmed 
Published: July 2019

Abstract
In this paper, we have studied the effect of thermal stress on the damage of fiber-matrix interface of a hybrid biocomposite composed of two natural fibers, Hemp, Sisal, and Starch matrix. Our genetic modeling used the nonlinear acoustic technique based on Cox’s analytical model, Weibull’s probabilistic model, and Lebrun’s model describing the thermal stress by the two coefficients of expansion. The stress applied to our representative elementary volume is a uni-axial tensile stress.
The numerical simulation shows that the Hemp- Sisal/Starch hybrid biocomposite is most resistant to thermal stresses as compared with Hemp/Starch biocomposite. It also shows that hybrid biocomposite materials have a high resistance to applied stresses (mechanical and thermal) compared to traditional materials and biocomposite materials. The results obtained in our study coincide perfectly with the results of Antoine et al., which showed through experimental tests that natural fibers perfectly improve the mechanical properties of biocomposite materials.