bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cerebral fat embolism following autologous fat injection in facial reconstruction: A case report
Authors: Chen Xiu-Ying , Shen Fa , Cheng Chang , Wang Yu-Han , Cheng Wen-Chao , Yuan De-Zhi , Huang Wen 
Published: November 2024

BACKGROUND
Autologous fat injection in facial reconstruction is a common cosmetic surgery. Although cerebral fat embolism (CFE) as a complication is rare, it carries serious health risks.
CASE SUMMARY
We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling surgery. After the surgery, the patient experienced symptoms including headache, nausea, vomiting, and difficulty breathing, which was followed by neurological symptoms such as slurred speech and left-sided weakness. Comprehensive physical examination and auxiliary investigations, including blood tests, head and neck computed tomography angiography, and cranial magnetic resonance diffusion-weighted imaging, were performed upon admission. The clinical diagnosis was acute cerebral embolism following facial fat filling surgery. Treatment included measures to improve cerebral circulation, dehydration for intracranial pressure reduction, nutritional support, and rehabilitation therapy for left limb function. The patient showed a significant improvement in symptoms after 2 weeks of treatment. She recovered left limb muscle strength to grade 5, had clear speech, and experienced complete relief of headache.
CONCLUSION
Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial reconstruction. To prevent these complications, plastic surgeons should enhance their professional knowledge and skills.
Optoelectronic oscillator using visible LEDs and plastic optical fibers
Authors: Ferreira Vitor T. , Magri Vanessa P. R. , Santos Alexandre C. T. , Ribeiro Ricardo M. 
Published: November 2024

This paper describes an optoelectronic oscillator (OEO) capable of accepting CW light as input and providing radio-frequency (RF) carriers as output. To the best of our knowledge, we are the first to describe an easy-to-assemble and low-cost OEO that uses visible LED sources with a standard 1 mm diameter plastic optical fiber as part of the oscillation ring. The gain is solely provided by a transimpedance pre-amplifier integrated with a photodetector. Self-oscillations occurred. Fundamental frequencies in the 7.7–26.5 MHz range were generated, since the length of the fiber and the bias current feeding the LED are both correctly tuned. A comprehensive approach is used to explain the operation of the OEO. The proposed OEO may be didactically useful for use in research or teaching laboratories by untrained people.
Influence of the size of the cubic atomic vapor cell on a Rydberg atomic microwave sensor
Authors: Zhang Liting , Li Zhonghao , Liu Shuai , Xu Shihong , Kong Jingxia , Zhao Rui , Guo Hao , Wen Huanfei , Li Xin , Ma Zongmin , Tang Jun , Liu Jun 
Published: November 2024

This study investigates the enhancement of the microwave (MW) electric (E) field due to the Fabry–Perot (FP) effect in cubic cells of varying sizes, and it is confirmed that the lower limit of MW power can be measured. Theoretical simulations and empirical validations are conducted for three vapor cells of different sizes. At a MW frequency of 23.904 GHz, the FP effect in the 10 mm cell is found to significantly enhance the MW E-field relative to larger cells (20 and 25 mm). The results show that, due to the existence of the FP effect, the lower limit of MW power can be measured in the cubic atomic vapor cells with different sizes. These findings contribute to the advancement of the vapor cell design for quantum accuracy measurements and the development of future atomic MW communication technologies.
Errors in the diagnosis of clinical hyperandrogenism in clinical practice using the example of telemedicine consultations «doctor-patient» and «doctor-doctor» at the Endocrinology Research Centre
Authors: Sheremetyeva E. V. , Andreeva E. N. , Melnichenko G. A. 
Published: November 2024

Hyperandrogenism syndrome (HA) is a large group of endocrine diseases that occur due to various pathogenetic mechanisms, but are united by the principle of similar clinical symptoms due to excessive quantity and/or quality (activity) of male sex hormones in the female body. HA is one of the most common pathologies of the endocrine system in women of reproductive age. Patients with HA seek help from various specialists: cosmetic defects — to a cosmetologist, menstrual irregularities and infertility — to a gynecologist, pediatricians (congenital dysfunction of the adrenal cortex), therapists and endocrinologists — remote consequences: dyslipidemia, arterial hypertension and carbohydrate metabolism disorders. Testosterone (T) occupies a key position in the hypothalamus-pituitary-gonads system. In women, it is synthesized by the adrenal cortex, ovarian cells, and is also formed in peripheral tissues. Russian clinical diagnostic laboratories have various diagnostic systems for determining all sorts of biochemical parameters and markers. The accuracy and correctness of the determination depend on the availability of an adequate and accessible method, as well as the characteristics of the woman’s somatic status, for example, the presence of obesity. The emergence and development of modern technology of high-performance liquid chromatography with tandem mass spectrometric detection, which provides high productivity, almost 100% selectivity, the necessary sensitivity and reproducibility, allows using HPLC-MS/MS as a method recommended by clinical guidelines for diagnosing biochemical hyperandrogenism, which allows excluding false diagnoses in routine clinical practice.
Meta-analysis of experimental studies of the effect of melatonin monotherapy on the levels of thyroid hormones and glucocorticoids in rats kept under standard condition
Authors: Kuzmenko N. V. , Tsyrlin V. A. , Pliss M. G. 
Published: November 2024

BACKGROUND: Melatonin is known to modulate circadian and seasonal rhythms in metabolism, reproduction, and behavior. However, the effect of exogenous melatonin supplementation on the functioning of the thyroid and adrenal glands in species without a clear seasonality in reproduction is still unclear.AIM: Using a meta-analysis of publications, to investigate the effect of melatonin monotherapy on the concentrations of pituitary thyroid-stimulating hormone, thyroid hormones (TG), pituitary adrenocorticotropic hormone and corticosterone (CS) in rats kept under standard laboratory conditions.MATERIALS AND METHODS: In our work, using the Review Manager 5.3 program, we conducted a meta-analysis of publications examining the effect of melatonin monotherapy on the functioning of the thyroid gland (22 papers) and adrenal glands (20 papers) in rats kept under standard conditions.RESULTS: According to the results of our meta-analysis, the effects of melatonin on the levels of TG and CS depend on the dose and duration of therapy. A decrease in TG and CS was associated with therapy lasting no more than 4-5 weeks and with high doses of melatonin. An increase in CS and a trend toward increased TG levels were observed with longer therapy. However, a few studies have observed a decrease in TG with very long-term melatonin therapy (≥32 weeks). Among all TGs, total thyroxine (T4) showed maximum sensitivity to exogenous melatonin, which indicates the influence of melatonin on the secretory function of the thyroid gland. In addition, melatonin increased the relative weight of the adrenal glands. There was no convincing evidence that the effects of melatonin were influenced by the route and timing of administration, or the timing of blood sampling.CONCLUSION: As a result, exogenous melatonin can modulate TG and CS levels, even in species without a clear seasonality in reproductive function.
Non-classical hormones from the fibroblast growth factor family
Authors: Gronskaia S. A. , Rusyaeva N. V. , Belaya Zh. E. , Melnichenko G. A. 
Published: November 2024

Fibroblast growth factors (FGFs) are a group of signaling molecules named for their ability to promote the growth and proliferation of fibroblasts and various other cell types. Typically, FGFs exert their effects locally by binding to receptors within the tissues where they are synthesized. However, certain members of this family, such as FGF 19, FGF 21, and FGF 23, diverge from this pattern. Following synthesis, these FGFs enter the bloodstream and act on distant organs and tissues by binding to their receptors and associated cofactors, thereby classified as non-classical hormones within the FGF family.The biological functions of FGFs are diverse and contingent upon the specific receptors and cofactors involved in their signaling pathways. For instance, FGF 19 and FGF 21 play crucial roles in regulating glucose and lipid metabolism, whereas FGF 23 primarily influences phosphorus metabolism. Given their varied roles, FGFs present promising targets for therapeutic interventions and drug development.This review aims to consolidate current understanding of FGF family hormones, elucidating their biological impacts and exploring their potential applications as therapeutic targets.
Analysis of the provision of medical care using telemedicine technologies at the endocrinology research centre
Authors: Nazarova A. S. , Prikazchikova S. S. , Kalashnikov V. Y. , Melnichenko G. A. , Mokrysheva N. G. 
Published: November 2024

BACKGROUND: In the first months after the pandemic of the COVID-19, the provision of medical care through telemedicine technologies took a leading position, in particular regarding endocrine nosologies. Meanwhile, at present, comprehensive information on telecommunications interaction between doctors of various medical organizations of the regions of the Russian Federation and employees of federal centers is insufficient, which determines the relevance of studying this topic.AIM: Analysis of the provision of medical care in remote interaction of medical workers using telemedicine technologies («doctor-doctor») between the Endocrinology Research Centre and the regions of the Russian Federation in 2019–2023.MATERIALS AND METHODS: A single-center, observational, single-sample study was conducted, including completed planned and urgent telemedicine consultations in the format of «doctor-doctor « in the fields of «endocrinology» and «pedia­tric endocrinology», conducted through a telemedicine system for remote consultations at federal and regional levels between 2019 and 2023. Data on the referral rate of medical personnel from the regions of the Russian Federation to the Endocrinology Research Centre for telemedicine consultations were analyzed, including annual dynamics of treatment, frequency of referrals from each region, nosological structure of referrals, and number of patients admitted to the center based on the results of these consultations. Analysis of interdepartmental cooperation between the Endocrinology Research Centre and other federal centers was also performed.RESULTS: In the period from 2019–2023, 14,475 telemedicine consultations «doctor-doctor» were conducted. In 2019, medical workers from 78 regions of the Russian Federation applied to the Endocrinology Research Centre. By 2023, this figure has increased to 88 (including newly annexed territories). The Yamalo-Nenets Autonomous Okrug, Tambov Region and Astrakhan Region were the leading regions in terms of the circulation of medicines at the Endocrinology Research Centre. In the nosological structure, the largest number of consultations in adult patients were conducted for acromegaly and primary hyperparathyroidism, in children for stunting and type 1 diabetes mellitus. In the period from 2019–2023, the Endocrinology Research Centre sent a total of 300 «outgoing» requests to 17 medical organizations.CONCLUSION: Consulting with the use of telemedicine technologies has become a convenient and multifunctional way of providing medical care. Further analysis of the place of telemedicine in practical healthcare will expand its capabilities, including considering the introduction of financing by the territorial fund of compulsory medical insurance for this area of medical activity.
Izkušnje z učnimi delavnicami za uvedbo naprednega procesa zdravstvene nege v klinično prakso
Authors: Klancnik Gruden Maja , Mihelič Zajec Andreja , Rebec Doroteja , Novak Anja , Pintar Babič Matejka , Lubi Tamara , Podlipnik Tanja , Medvešček Smrekar Maja 
Published: November 2024

Uvod: Uporaba naprednega procesa zdravstvene nege predstavlja za medicinske sestre v praksi velik izziv, zato so bile za njih organizirane učne delavnice za uvedbo standardiziranih jezikov zdravstvene nege. Namen raziskave je bil ugotoviti izkušnje medicinskih sester z zvedenim izobraževanjem.Metode: Uporabljena je bila kvalitativna deskriptivna metoda. Instrument za zbiranje podatkov je bil evalvacijski list s tremi odprtimi vprašanji. V priložnostni vzorec je bilo vključenih 160 medicinskih sester, ki so se udeležile serije učnih delavnic v letih 2020 in 2021. Kvalitativna analiza zapisov je bila izvedena s tematsko mrežo.Rezultati: Na osnovi analize zapisov je bilo oblikovano tematsko omrežje »izkušnje udeležencev z učno delavnico« z dvema skupnima temama: »izvedba učne delavnice« in «uporaba v praksi«. V okviru prve skupne teme so bile izkušnje udeležencev večinsko pozitivne, negativno je bilo ocenjeno le gradivo. V okviru druge skupne teme so prevladovali predlogi za uvedbo naprednega procesa zdravstvene nege v prakso, negativne izkušnje so se nanašale na zahtevnost vsebine, pozitivne pa na vpogled v znanja prihodnosti.Diskusija in zaključek: Udeleženci učnih delavnic so bili v večini zadovoljni z izvedbo učnih delavnic za uvedbo naprednega procesa zdravstvene nege, hkrati so izrazili tudi skrb o utemeljenosti uvajanja standardiziranega jezika v prakso v trenutni okoliščini pomanjkanja medicinskih sester. Nadaljevati je treba s sistematičnim formalnim, kot tudi neformalnim izobraževanjem medicinskih sester, ki delujejo v klinični praksi, pri čemer je za doseganje večjega učinka in večje motiviranosti treba uporabiti udeležencemprilagojene načine izobraževanja.
Duhovna oskrba žensk po spontani prekinitvi nosečnosti
Authors: Macuh Zala , Fekonja Zvonka , Franc Rosemarie , Kmetec Sergej , Mlinar Reljić Nataša 
Published: November 2024

Uvod: Prekinitev nosečnosti predstavlja stisko za žensko, partnerja in družino. Pomembno je, da zdravstveno osebje v celovito zdravstveno obravnavo vključi tudi duhovno oskrbo. Namen pregleda literature je ugotoviti, kakšno duhovno oskrbo najpogosteje potrebujejo ženske po spontani prekinitvi nosečnosti.Metode: Izveden je bil sistematični pregled literature v bazah podatkov CINAHL Ultimative, Science Direct, Wiley Online Library in Web of Science z iskalnim nizom v angleškem jeziku. Za prikaz iskanja, pregleda in izbora člankov za analizo je bil uporabljen diagram poteka PRISMA. Izvedena je bila kritična ocena člankov s kontrolnimi seznami Joanna Briggs Institute. Zbrani podatki so bili analizirani po metodi vsebinske analize.Rezultati: Iskanje je dalo 490 zadetkov, od katerih je bilo v končno analizo vključenih devet raziskav. Glavno kategorijo smo oblikovali na osnovi treh podkategorij: (1) čustvovanje in počutje, (2) medosebni odnosi in (3) duhovna rast.Diskusija in zaključek: Ugotovitve kažejo, da je pri zagotavljanju duhovne oskrbe ključno razumevanje duhovnih potreb in stisk, ki jih doživljajo ženske po spontani prekinitvi nosečnosti. Poleg medicinske oskrbe si zelo želijo tudi dobro duhovno oskrbo. Ženske svoje duhovne potrebe izražajo skozi čustva in občutke, ki jih morajo medicinske sestre in babice prepoznati ter se nanje ustrezno odzvati. Duhovna oskrba mora temeljiti na razumevanju, sočutju in podpori.
Penalty method for unilateral contact problem with Coulomb's friction in time-fractional derivatives
Authors: Essafi Lakbir , Bouallala Mustapha 
Published: November 2024

Abstract
The purpose of this work is to study a mathematical model that describes a contact between a deformable body and a rigid foundation. A linear viscoelastic Kelvin-Voigt constitutive law with time-fractional derivatives describes the material’s behavior. The contact is modeled with Signorini’s condition coupled with Coulomb’s friction law. We derive a variational formulation of the model, and we prove the existence of a weak solution using the theory of monotone operators and Caputo derivative and the Rothe method. We also introduce the penalized problem and prove its solvability using the Galerkin method. Furthermore, we study the convergence of its solution to the solution of the original problem as the penalization parameter tends to zero.
From Literature 2.0 to Twitterature or Xerature: The Birth and Canonicity of Nigerian Xerature
Authors: Waliya Yohanna Joseph , Ajimase Angela Awhobiwom , David Franklin Ubi 
Published: November 2024

Abstract
Nigerian literature has long used paper and film as primary media for cultural expression and exporting African culture and civilisation. However, the advent of datafication and botification in the turn of millennium, particularly within social media, has brought forth a new era. This shift is peculiarly evident in the ‘Twitterverse’, where Nigerian Twitterature, or ‘Xerature’, emerged in 2014, largely due to the work of Nigerian-American novelist Teju Cole. His minimalist ‘Twittories’ addressed Nigeria’s socio-political landscape. This article aims to raise awareness, trace the origins, and define this evolving genre while proposing canonisation and methodological approaches to its study reported in a sustained reading of Hafsat Dauda (@HafsahDauda)’s Las, Las Nigeria is Home 2020.
Bridging the Gap – Religionsdidaktische Unterrichtsforschung und -entwicklung im Design-Based Research (DBR)
Authors: Pirner Manfred L. , Fleischmann Augustine L. 
Published: November 2024

Zusammenfassung
Im Design-Based Research (DBR) – in Deutschland auch: fachdidaktische Entwicklungsforschung – werden Lehr-Lern-Szenarien (weiter-)entwickelt, in mehreren Zyklen erprobt, evaluiert und verbessert. Damit werden wie in kaum einem anderen Forschungsformat Unterrichtsforschung und -entwicklung miteinander verbunden. Das Format ist seit einigen Jahren auch in der religionsdidaktischen Forschung gewinnbringend verwendet worden. Exemplarisch wird von einem aktuellen DBR-Projekt zur Integration von Menschenrechtsbildung in den Religionsunterricht berichtet.
Praxeologie als Brücke zwischen religionspädagogischer Unterrichtsforschung und Praxis
Authors: Roose Hanna 
Published: November 2024

Zusammenfassung
Religionspädagogische Unterrichtsforschung ist in der Didaktik überwiegend defizitorientiert ausgerichtet. Sie gleicht die unterrichtliche Praxis mit didaktischen Erwartungen ab, die von außen an sie herangetragen werden, selber aber durch die Praxis nicht infrage gestellt werden. Die Praxeologie dient angesichts dieser Kluft zwischen didaktischen Maßstäben und (defizitärer) unterrichtlicher Alltagspraxis als Brücke. Sie leistet über eine „regularist notion“ von wiederholbaren und sich wiederholenden Praktiken (Routinen) einen Beitrag zur fachspezifischen Lernkulturforschung, die die Eigenlogik von Alltagspraxis im Religionsunterricht beschreibt. Und sie ermöglicht über eine „normative notion“ von Praktiken ein Gespräch über Normen, in dem didaktisch herangetragene Normen einer Relativierung bzw. Kritik unterworfen werden.
Post-Discharge Cardiovascular Complications in Noncardiac Surgery: Incidence and Prediction
Authors: Sokolov D. A. , Kozlov I. A. 
Published: November 2024

The aim of this study was to assess the incidence of cardiovascular complications (CVC) within 12 months after vascular surgery and to analyze inpatient perioperative examination data to identify potential predictors. Materials and Methods. A prospective cohort study included 103 patients aged 66 years [61–70] who underwent vascular surgery. Clinical outcomes within 12 months after surgery, including CVC and/or other cardiac events (composite outcome) and cardiac death, were assessed by telephone interviews with patients or their relatives. Patient physiological parameters, comorbidities, cardiac risk indices (CRI), platelet-lymphocyte ratio (PLR), concentration of N-terminal pro-B-type natriuretic peptide (NT-proBNP), and other parameters were obtained and analyzed from medical records. Logistic regression and ROC analysis were used to assess the predictive power of the investigated indicators. Results. The composite outcome was recorded in 33 % of cases and cardiac death occurred in 6.8 %. The risk of the composite outcome was associated with ASA class (OR 2.7413; 95 % CI 1.1126–6.7541), whereas the risk of perioperative myocardial infarction or cardiac arrest was associated with CRI (OR 1. 6051; 95 % CI 0.6645–2.0215), American University of Beirut (AUB) CRI (OR 2.1106; 95 % CI 1.0260–4.3414), PLR (1.0120; 95 % CI 1.0018–1.0222), and NT-proBNP concentration during hospitalization. Concurrent congestive heart failure (OR 5.0658; 95 % CI 1.2400–20.6956), revised CRI (OR 2.1024; 95 % CI 1.0572–4.1813), Khoronenko CRI (OR 103.76; 95 % CI 1.8752–5796.55), AUB CRI (OR 3.1902; 95 % CI 1.1040–9.2181), and NT-proBNP concentration all increased the risk of cardiac death. Predischarge NT-proBNP levels < 179 pg/mL (OR 1.0071; 95 % CI 1.0038–1.0104; AUC 0.795) and maximum postoperative NT-proBNP levels were reliable predictors of the composite outcome. The most effective predictor of postoperative mortality was a maximum NT-proBNP concentration > 303 pg/mL after surgery (OR 1.0039; 95 % CI 1.0015–1.0063; AUC 0.836). Conclusion. CVC developed in 33 % of patients within 12 months after vascular surgery, with cardiac death occurring in 6.8 % of cases. An NT-proBNP concentration > 179 pg/mL before hospital discharge or a maximum NT-proBNP concentration > 248 pg/mL in the postoperative period predicted CVC within one year. Postoperative NT-proBNP concentration > 303 pg/mL was a strong predictor of one-year cardiac mortality. Other factors associated with the risk of postoperative CVC did not provide an accurate prognosis.