bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Self Action dan Self Efficacy terhadap Kreativitas Mahasiswa dalam Kegiatan Praktikum Fisika Dasar Jurusan Pendidikan Fisika
Authors: Kadir Fitriani 
Published: October 2019

Penelitian ini bertujuan mengetahui sejauh mana self action dan self efficacy mahasiswa dalam kegiatan praktikum dan untuk mengetahui apakah terdapat pengaruh antara self action dan self efficacy terhadap kreativitas mahasiswa dalam kegiatan praktikum Fisika Dasar Jurusan Pendidikan Fisika Fakultas Tarbiyah dan Keguruan UIN Alauddin Makassar. Jenis penelitian ini adalah penelitian deskriptif regresional, dimana penelitian ini berusaha mengambarkan pengaruh self action dan self efficacy terhadap kreativitas mahasiswa dalam kegiatan praktikum fisika dasar. Instrumen penelitian yang digunakan adalah angket dan lembar observasi. Simpulan yang diperoleh ialah terdapat pengaruh yang signifikan antara self action dan self efficacy terhadap kreativitas mahasiswa dalam kegiatan praktikum Fisika Dasar Jurusan Pendidikan Fisika Fakultas Tarbiyah dan Keguruan UIN Alauddin Makassar.Kata kunci: Aksi Diri, Keyakinan Diri, Kreativitas This study is to determine the extent of self-action and self-efficacy of students in practicum activities and to determine whether there is an effect of self-action and self-efficacy on students` creativity in basic physics practicum Majoring in Physics Education, Faculty of Tarbiyah and Teacher Training UIN Alauddin Makassar. The type of this research is descriptive regression, which attemps to describe the effect of self-action and self-efficacy on students` creativity in basic phyhsics practicum activities. The research instruments used were questionnaires and observation sheets. The conclusions are thet there is a significant effect between self-action and self-efficacy on students` creativity in basic physics practicum Majoring in Physics Education, Faculty of Tarbiyah and Teacher Training UIN Alauddin Makassar.Keywords: Self Acton, Self Efficacy, Creativity
The Implementation of Guided Discovery Learning Model Based on Experiments toward Science Process Skills
Authors: Nurlina Nurlina 
Published: October 2019

This study aims to determine (1) science process skills students in class XI IPA 3 Pamboang 1 Public High School before being taught using a guided discovery learning model (2) science process skills students in class XI IPA 3 Pamboang 1 Public High School after being taught using a guided discovery learning model(3) science process skills students in class XI IPA 3 Pamboang 1 Public High School before and after being taught using a guided discovery learning model. This type of research is pre-experimental research with design The One group pretest – posttest design which involves independent variable namely the learning model guided discovery and the dependent variable is science process skills. The subjects of the study population were students of class XI IPA of SMA Negeri 1 Pamboang in the school year 2018/2019 which consists of 3 classes with selected samples random sampling (random class) so that it is obtained in class XI IPA 3. The results showed that the pretest of students obtained an average score of science process skills of 15.65. With a standard deviation of 4.95. While the posttest obtained an average score of 20.90 with a standard deviation of 4.62 and the average score of the normalized gain test is 0.36. So it can be concluded that the science process skills of students increase in the medium category after being applied to the Guided Discovery learning model.Keywords: Learners, Guided Discovery, Science Process SkillsPenelitian ini bertujuan untuk mengetahui (1) keterampilan proses sains peserta didik kelas XI IPA 3 SMA Negeri 1 Pamboang sebelum diajarkan menggunakan model pembelajaran discovery terbimbing (2) keterampilan proses sains peserta didik kelas XI IPA 3 SMA Negeri 1 Pamboang setelah diajarkan menggunakan model pembelajaran discovery terbimbing (3) keterampilan proses sains peserta didik kelas XI IPA 3 SMA Negeri 1 Pamboang sebelum dan setelah diajar dengan model pembelajaran Discovery Terbimbing. Jenis penelitian ini adalah penelitian pra eksperimen dengan desain The One group pretest – posttest design yang melibatkan variabel bebas yaitu model pembelajaran discovery terbimbing dan variabel terikat yaitu keterampilan proses sains. Subyek populasi penelitian adalah peserta didik kelas XI IPA SMA Negeri 1 Pamboang tahun ajaran 2018/2019 yang terdiri dari 3 kelas dengan sampel di pilih secara random sampling (kelas acak) sehingga diperoleh kelas XI IPA 3. Hasil penelitian menunjukkan pada pretest peserta didik memperoleh skor rata-rata keterampilan proses sains sebesar 15,65. Dengan standar deviasi sebesar 4,95. Sedangkan pada posttest diperoleh skor rata-rata sebesar 20,90 dengan standar deviasi sebesar 4,62 dan skor rata-rata uji gain ternormalisasi sebesar 0,36. Sehingga dapat disimpulkan bahwa keterampilan proses sains peserta didik meningkat dalam kategori sedang setelah diterapkan model pembelajaran Discovery Terbimbing.Kata kunci: Peserta Didik, Discovery Terbimbing, Keterampilan Proses Sains
Erupción polimorfa del embarazo, un diagnóstico diferencial de las reacciones graves por medicamentos
Authors: Calle Ana , Guevara-Saldaña Liliana , Cardona Ricardo 
Published: October 2019

Antecedentes: La erupción polimorfa del embarazo es una patología que se presenta normalmente en el último trimestre de los embarazos y afecta aproximadamente a 0.5 % de las mujeres en esta condición. No se ha relacionado con medicamentos, pero podría imitar cualquier reacción grave por medicamentos tardías.Caso clínico: Mujer con cuadro clínico sugestivo de erupción polimorfa del mbarazo durante el último trimestre del embarazo. Fue valorada por alergología, donde se consideró erupción polimorfa del embarazo, sin embargo, se decidió realizar pruebas cutáneas: punción cutánea, pruebas intradérmicas y prueba de parche con medicamentos implicados, todas con resultados negativos.Conclusiones: Las reacciones graves por medicamentos son un reto para el profesional de la salud. En el manejo agudo, la identificación y suspensión del medicamento implicado son la piedra angular del tratamiento, sin embargo, numerosas pacientes están polimedicadas, lo que dificulta identificar la causa subyacente. Es recomendable una valoración por alergología como parte del manejo multidisciplinario óptimo de cada paciente, con el fin de lograr detectar la sustancia implicada como causal de la enfermedad y evitar restricciones innecesarias.
Alergia a vegetales pertenecientes a la familia de las solanáceas
Authors: Tomás-Pérez Margarita , Hernández-Martín Irene , Fernández de Alba-Porcel Isabel , Pagola María Jesús , Carretero Pedro , Domínguez-Ortega Javier , Lluch-Bernal María Magdalena , Caballero María Luisa , Quirce Santiago 
Published: October 2019

Antecedentes: Aunque se ha descrito reactividad cruzada con alimentos vegetales y látex, la alergia a la papa y al tomate es infrecuente. Objetivo: Estudiar los diferentes patrones de sensibilización en pacientes alérgicos a la patata o tomate.Métodos: Se realizaron pruebas de punción cutánea con extractos y alimentos frescos, determinación de IgE específica y detección de alérgenos mediante SDS-PAGE e IgE-Immunoblotting con extractos de patata y tomate crudos y calientes.Resultados: En 10 pacientes se detectaron alérgenos termoestables a extracto de patata, uno de peso molecular compatible con Sola t 1 (43 kDa, patatina) y otro de 14-22 kDa que podría corresponder a los alérgenos Sola t 4 (16 kDa), Sola t 2 y Sola t 3 (21 kDa); en dos pacientes alérgicos a la patata y dos alérgicos al tomate se detectó un alérgeno termoestable de aproximadamente 42 kDa. En un paciente alérgico al tomate se detectó un alérgeno termoestable compatible con Sola l 2 (50 kDa); había presentado síndrome de alergia oral con algunos tipos de patatas y mostró mayor reactividad IgE a dos alérgenos termoestables de la patata.Conclusiones: Los patrones de sensibilización a los alérgenos fueron similares en los pacientes, independientemente de los síntomas. Se ha detectado un nuevo alérgeno implicado en la alergia a las solanáceas.
Flujometría versus espirometría para el diagnóstico de asma en adultos
Authors: Herrera-Sánchez Andrea , Álvarez-Chavez Fabián Eduardo , Castillo-Hernández María C. , Orihuela Oscar , Guevara-Balcázar Gustavo , Martínez-Godínez María de los Ángeles , González-Virla Baldomero 
Published: October 2019

Antecedentes: El diagnóstico de asma se confirma con espirometría: VEF1 (volumen espiratorio forzado del primer segundo)/CVF (capacidad vital forzada) < 80 %, con reversibilidad (VEF1 >12 % o 200 mL) tras utilizar salbutamol. El flujómetro es barato y fácil de utilizar, mide el flujo espiratorio forzado, cuya reversibilidad > 20 % sugiere asma.Objetivo: Conocer sensibilidad, especificidad y valores predictivos positivos y negativo del flujómetro.Métodos: Estudio transversal, observacional, comparativo. Se incluyó a individuos > 18 años sin contraindicaciones para espirometría, quienes fueron sometidos a espirometría y flujometría y se les aplicó el Asthma Control Test. Se calculó sensibilidad, especificidad y valores predictivos positivo y negativo de la flujometría. Se realizó curva ROC para conocer el punto de corte de mayor sensibilidad y especificidad.Resultados: De 150 pacientes, 66 % fue del sexo masculino; la mediana de edad fue de 38 años. Conforme los criterios de Global Initiative for Asthma 2018, 58.7 % estaba controlado. La sensibilidad de la flujometría fue de 47 %, la especificidad de 87 %, valor predictivo positivo de 54.8 % y negativo de 84 %. La flujometría mostró mayor especificidad con VEF1 < 59 %. El punto de corte de mayor sensibilidad y especificidad fue una reversibilidad de 8 %, con área bajo la curva de 0.70.Conclusiones: El flujómetro tiene mayor sensibilidad en obstrucciones de vía aérea; es de utilidad cuando no se cuenta con un espirómetro.
Alergia a metilprednisolona
Authors: Pérez-Aragón Ana Josefa , Díaz-Molina Manuel , Romero-Paniagua María Teresa , Martínez-Cañavate Ana 
Published: October 2019

Los corticoides son fármacos ampliamente utilizados en la práctica médica debido a su potente efecto antiinflamatorio e inmunomodulador. Si bien la mayoría de las reacciones secundarias son muy conocidas, las alérgicas son infrecuentes; la hidrocortisona y la metilprednisolona constituyen los fármacos más comúnmente implicados. Se ha estimado 0.3 % de incidencia de reacciones alérgicas, algunas graves, por lo que la posibilidad de su ocurrencia debe ser considerada cuando se emplean estos medicamentos.
Importancia de los centros de excelencia de la Organización Mundial de Alergia
Authors: Sánchez-Borges Mario , González-Diaz Sandra Nora , Rosenwasser Lanny , Ansotegui Ignacio 
Published: October 2019

La Organización Mundial de Alergia (World Allergy Organization) es una federación de sociedades nacionales y regionales de alergia e inmunología clínica cuya misión es promover el desarrollo de estas especialidades a través de programas educativos en congresos, simposios y conferencias en diferentes partes del mundo. Esta alianza mundial de sociedades científicas y profesionales promueve la excelencia en la atención médica de la población mediante la educación, el entrenamiento y la investigación. Actualmente 103 Sociedades Nacionales y Regionales de Alergia e Inmunología Clínica pertenecen a la Organización Mundial de Alergia (https://worldallergy.org).
MENDIDIK ANAK USIA DINI DENGAN BERLANDASKAN PEMIKIRAN TOKOH ISLAM AL-GHAZALI
Authors: Rahmawati Miya 
Published: October 2019

Al-Ghazali merupakan salah satu tokoh Muslim yang pemikirannya sangat luas dan mendalam dalam berbagai hal diantaranya dalam masalah pendidikan. Konsep Pendidikan anak yang diusung oleh Al-Ghazali berpijak pada Al-Qur'an dan As-Sunnah sebagai dasar pendidikan anak. Anak yang lahir menurut al-ghazali suci dan bersih orang tua lah yang akan bertanggung jawab mendidiknya. Terdapat dua pendidikan anak tahapan janin dan tahapan kanak-kanak (thifl). Pokok pemikiran al-ghazali dalam mendidik anak : Pentingnya peran orang tua dan pendidikan akhlak bagi anak usia dini, Seimbangkan antara perintah dengan keteladanan. Gunakan metode pengajaran yang sesuai dengan minat dan bakatnya (kecerdasan jamak) Berikan waktu anak untuk bermain Berikan kegiatan positif di waktu luangnya Reward and Punishment. Pendidikan yang dirumuskan Al-Ghazali mencakup banyak aspek yaitu pendidikan keimanan, pendidikan akhlak, pendidikan 'aqliyah, pendidikan sosial dan pendidikan jasmani. Mengenai metode Al-Ghazali menganjurkan penggunaan metode yang bervariasi yang harus disesuaikan dengan tahap perkembangan akal fikiran anak. Seperti hafalan, pemahaman, pembiasaan, latihan dan lain sebagainya. Kata Kunci : Mendidik Anak Usia Dini, Pemikiran, Al-Ghazali
A Close Look at Echium amoenum Processing, Neuroactive Components, and Effects on Neuropsychiatric Disorders
Authors: Nouri Mohammad , Farajdokht Fereshteh , Torbati Mohammadali , Ranjbar Kuchaksaray Fatemeh , Hamedyazdan Sanaz , Araj-khodaei Mostafa , Sadigh-Eteghad Saeed 
Published: October 2019

Pharmacological researches in the area of herbal medicine have considerably increased over the last two centuries. Echium amoenum (known as Gol-e-Gavzaban in Persian) is a medicinal plant that has been widely used in Iranian folk medicine. In this review, databases including PubMed, Scopus, and Google Scholar were searched up. Data collecting was completed by January 2019 and available scientific reports regarding the processing methods, main chemical constituents, and effects of E. amoenum on different neuropsychiatric disorders are summarized. Thirteen five studies met the inclusion criteria. According to results, the important phytochemicals of the plant was phenolic compounds, fatty acids, rosmarinic acid, anthocyanidins, and flavonoids. Also, experimental and clinical studies demonstrated the effectiveness of E. amoenum in the treatment of several neuropsychiatric disorders such as anxiety, depression, ischemic stroke, seizure, Alzheimer’s disease, and pain. Many of these effects are, at least in part, due to its rosmarinic acid or polyphenolic compounds such as flavonoids and natural pigments such as anthocyanins. Also, fatty acids such as gamma-linolenic acid play critical role in neuroactive properties of this herb. Among these effects, only the antidepressant and anxiolytic properties of the plant extract have been examined both experimentally and clinically. There was some controversy over its toxicity effects. It seems that E. amoenum protects neurons via attenuation of oxidative stress and inflammation as well as blocking of apoptosis in the nervous system. However, more studies are necessary for assessing exact mechanisms of action in neuropsychiatric disorders, finding of bioactive ingredients, and processing methods of this plant. [GMJ.2019;8:e1559]
Surgical strategy for focal cortical dysplasia based on the analysis of the spike onset and peak zones on magnetoencephalography
Authors: Shirozu Hiroshi , Hashizume Akira , Masuda Hiroshi , Kakita Akiyoshi , Otsubo Hiroshi , Kameyama Shigeki 
Published: October 2019

OBJECTIVEThe aim of this study was to elucidate the surgical strategy for focal cortical dysplasia (FCD) based on the interictal analysis on magnetoencephalography (MEG). For this purpose, the correlation between the spike onset zone (Sp-OZ) and the spike peak zone (Sp-PZ) on MEG was evaluated to clarify the differences in the Sp-OZ and its correlation with Sp-PZ in FCD subtypes to develop an appropriate surgical strategy.METHODSForty-one FCD patients (n = 17 type I, n = 13 type IIa, and n = 11 type IIb) were included. The Sp-OZ was identified by the summation of gradient magnetic-field topography (GMFT) magnitudes at interictal MEG spike onset, and Sp-PZ was defined as the distribution of the equivalent current dipole (ECD) at spike peak. Correlations between Sp-OZ and Sp-PZ distributions were evaluated and compared with clinical factors and seizure outcomes retrospectively.RESULTSGood seizure outcomes (Engel class I) were obtained significantly more often in patients with FCD type IIb (10/11, 90.9%) than those with type IIa (4/13, 30.8%; p = 0.003) and type I (6/17, 35.3%; p = 0.004). The Sp-OZ was significantly smaller (1 or 2 gyri) in type IIb (10, 90.9%) than in type IIa (4, 30.8%; p = 0.003) or type I (9, 53.0%; p = 0.036). Concordant correlations between the Sp-OZ and Sp-PZ were significantly more frequent in type IIb (7, 63.6%) than in type IIa (1, 7.7%; p = 0.015) or type I (1, 5.8%; p = 0.004). Complete resection of the Sp-OZ achieved significantly better seizure outcomes (Engel class I: 9/10, 90%) than incomplete resection (11/31, 35.5%) (p = 0.003). In contrast, complete resection of the Sp-PZ showed no significant difference in good seizure outcomes (9/13, 69.2%) compared with incomplete resection (11/28, 39.3%).CONCLUSIONSThe Sp-OZ detected by MEG using GMFT and its correlation with Sp-PZ were related to FCD subtypes. A discordant distribution between Sp-OZ and Sp-PZ in type I and IIa FCD indicated an extensive epileptogenic zone and a complex epileptic network. Type IIb showed a restricted epileptogenic zone with the smaller Sp-OZ and concordance between Sp-OZ and Sp-PZ. Complete resection of the Sp-OZ provided significantly better seizure outcomes than incomplete resection. Complete resection of the Sp-PZ was not related to seizure outcomes. There was a definite difference in the epileptogenic zone among FCD subtypes; hence, an individual surgical strategy taking into account the correlation between the Sp-OZ and Sp-PZ should be considered.
Cerebrospinal fluid macrophage migration inhibitory factor: a potential predictor of cerebral vasospasm and clinical outcome after aneurysmal subarachnoid hemorrhage
Authors: Kwan Kevin , Arapi Orseola , Wagner Katherine E. , Schneider Julia , Sy Heustein L. , Ward Mary Frances , Sison Cristina P. , Li Chunyan , Eisenberg Mark B. , Chalif David , Narayan Raj K. , Miller Edmund J. , Ledoux David 
Published: October 2019

OBJECTIVEIn patients with aneurysmal subarachnoid hemorrhage (aSAH), poor outcomes have been shown to be correlated with subsequent cerebral vasospasm (CV) and delayed cerebral ischemia (DCI). The identification of novel biomarkers may aid in the prediction of which patients are vulnerable to developing vasospasm, cerebral ischemia, and neurological deterioration.METHODSIn this prospective clinical study at North Shore University Hospital, patients with aSAH or normal pressure hydrocephalus (NPH) with external ventricular drains were enrolled. The concentration of macrophage migration inhibitory factor (MIF) in CSF was assessed for correlation with CV or DCI, the primary outcome measures.RESULTSTwenty-five patients were enrolled in the aSAH group and 9 were enrolled in the NPH group. There was a significant increase in aggregate CSF MIF concentration in patients with aSAH versus those with NPH (24.4 ± 19.2 vs 2.3 ± 1.1 ng/ml, p < 0.0002). Incidence of the day of peak MIF concentration significantly correlated with the onset of clinical vasospasm (rho = 0.778, p < 0.0010). MIF concentrations were significantly elevated in patients with versus those without evidence of DCI (18.7 ± 4.93 vs 8.86 ± 1.28 ng/ml, respectively, p < 0.0025). There was a significant difference in MIF concentrations between patients with infection versus those without infection (16.43 ± 4.21 vs 8.5 ± 1.22 ng/ml, respectively, p < 0.0119).CONCLUSIONSPreliminary evidence from this study suggests that CSF concentrations of MIF are correlated with CV and DCI. These results, however, could be confounded in the presence of clinical infection. A study with a larger patient sample size is necessary to corroborate these findings.
Preoperative tumor-associated epilepsy in patients with supratentorial meningioma: factors influencing seizure outcome after meningioma surgery
Authors: Schneider Matthias , Güresir Ági , Borger Valeri , Hamed Motaz , Rácz Attila , Vatter Hartmut , Güresir Erdem , Schuss Patrick 
Published: October 2019

OBJECTIVEBoth pre- and postoperative seizures comprise common side effects that negatively impact patient quality of life in those suffering from intracranial meningioma. Therefore, seizure freedom represents an important outcome measure in meningioma surgery. In the current study the authors analyzed their institutional database to identify risk factors for postoperative seizure occurrence after surgical meningioma therapy in patients with preoperative symptomatic epilepsy.METHODSBetween February 2009 and April 2017, 187 patients with preoperative seizures underwent resection of supratentorial meningioma at the authors’ institution. Seizure outcome was assessed retrospectively 12 months after tumor resection according to the International League Against Epilepsy (ILAE) classification and stratified into favorable (ILAE class I) versus unfavorable (ILAE classes II–VI). A univariate and multivariate analysis was performed to identify factors influencing seizure outcome.RESULTSOverall 169 (90%) of 187 patients with preoperative seizures achieved favorable outcome in terms of seizure freedom after meningioma resection. Multivariate analysis revealed peritumoral edema > 1 cm in maximal diameter and WHO grade II and III tumors, as well as a low extent of resection (Simpson grades III–V) as independent predictors for postoperative unfavorable seizure outcome.CONCLUSIONSSurgery is highly effective in the treatment of seizures as common side effects of supratentorial meningioma. Furthermore, the present study identified several significant and independent risk factors for postoperative seizure occurrence, enabling one to select for high-risk patients that require special attention in clinical and surgical management.