bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE INFLUENCE OF EXTERNAL AND INTERNAL FACTORS ON THE CHEWING EFFICIENCY OF THE DENTITION
Authors: Лазарев Сергей , Lazarev Sergey , Ле Тху Чанг , Le Thu Chang 
Published: May 2019

Subject. Going upright in human evolution changed the position of the spinal column and head. The position of the spine affects the occlusion through the rotational movements of the first cervical vertebra. The dentofacial system also evolved: the gaps disappeared between the canines and the adjacent teeth; sex differences of teeth were almost erased. As a result, the chewing became more adapted to speech reducing the dominant influence of the canines. Food influenced on the shape of teeth, the occlusion, the lower jaw movement. People use premolars and first molars for chewing soft food, which diminished the chewing efficiency of second molars. The function-dominant chew side also develops dentofacial system.
Aim ― research regularities of jaw chewing in stress strain.
Methods. Silicone occlusion impressions were obtained from each subject in stress conditions and physical activities.
Results. Subjects with a dominant right hand have more amounts of match supracontacts at the right jaw side than at the left one. At opposite side of the spectrum, subjects with a dominant left hand have more amounts of match supracontacts at the left jaw side than at the right one. Ambidextrousnesses have approximately equal amounts at the right and left jaw sides. This is evidence of the force movement at the dominant chewing side.
Conclusion. While subjects were falling, the low jaw moved forward resting up against on the canines. In other words, in weightlessness condition the falling subjects were searching for the point of support, which was the occlusion. In the results, it redirected and reduced the kinetic energy of falling bodies and levers of operating forces. The number of supracontact points during lifting is less than in the position of weightlessness. In other words, during the weight lifting the subjects have support points: the lower back and legs. And the occlusion becomes the third point of support only when lifting the extreme physical exertions.
THE FREQUENCY OF COMBINATION OF ORAL LICHEN PLANUS WITH SOMATIC PATHOLOGY AND LOCAL UNFAVORABLE FACTORS OF THE ORAL CAVITY
Authors: Анисимова Ирина , Anisimova Irina , Симонян Лаура , Simonyan Laura 
Published: May 2019

Background. In this article, we studied the frequency of combination of oral lichen planus with somatic pathology. The analysis of the survey, testing of individuals with oral lichen planus, laboratory blood counts; personalized advisory opinions of the local therapists. The influence of local adverse factors was studied by analyzing the indicators of galvanic current and the oral hygiene index.
Objectives ― to study the frequency of combination of lichen planus with somatic pathology, the level of psycho-emotional status of patients, the role of local adverse factors in the oral cavity.
Methods. There were analyzed two groups of patients in the age of 24―65 years. The main group (numbered in 22 people), included patients with oral lichen planus and control group (numbered in 15 people) combined people without pathology of the oral mucosa. The main group was divided into two subgroups I (numbered in 11 people), combined patients with a typical form of oral lichen planus and subgroup II (numbered in 11 people) included patients with an erosive-ulcerative form of oral lichen planus. Clinical and laboratory examinations were conducted by a local therapist to identify somatic pathology. Filled in the “health questionnaire” and tested by the method of Zung. Determined the concentration of glucose in blood; blood pressure indicators; the level of hygiene and galvanic current.
Results. Questioning showed that patients with oral lichen planus have somatic pathology. Testing according to Zung's method revealed psycho-emotional disorders. Clinical and laboratory examination by a therapist revealed 100 % somatic pathology, concentration of glucose in blood and blood pressure in most individuals exceeded WHO standards. Analysis of the hygiene index showed a low level of oral hygiene; analysis of galvanometry revealed the presence of galvanic current in the oral cavity.
Conclusions. Among all patients with oral lichen planus somatic pathology was detected in 100 % of cases. Lichen planus proceeds against the background of psycho-emotional disorders. Local unfavorable factors of the oral cavity (low level of hygiene and galvanic current) aggravate the course of lichen planus, slow down the regeneration.
STUDYING THE DENTAL STATUS OF MILITARY WITH PAIN SYNDROMES OF THE ORAL CAVITY IN VARIOUS CLIMATIC GEOGRAPHIC CONDITIONS
Authors: Никитенко Виталий , Nikitenko Vitaliy , Борисова Элеонора , Borisova Eleonora , Балин Владимир , Balin Vladimir , Рощупкина Инна , Roshchupkina Inna 
Published: May 2019

Importance. Currently, the problem of adverse effects of climatic conditions on human health, in particular, on the health of military, is becoming increasingly important. The emergence of various neuralgia of a number of cranio-facial nerves, often accompanied by atypical pain in the temporomandibular joints, masticatory muscles are more severe in the Arctic regions; quite often there are complications during dental interventions, manifested in the form of pain syndromes of the maxillofacial region.
Objective ― the dental status of 360 military suffering from pain syndromes in the maxillofacial region and serving in areas with different climatogeographic conditions was studied.
Methodology. Patients were divided into clinical groups. The first group consisted of soldiers from St.-Petersburg and Leningrad region (group A). The second group consisted of men serving in the Far North (group B). Clinical methods of examination included visual examination, palpation, examination of the oral cavity, assessment of the hygienic state of the oral cavity and determination of periodontal indices, bite features, logging of pathological changes in hard tissues of teeth and occlusive relationships. The intensity of pain severity was assessed by visual analog scale. The highest percentage (62.72%) among the diseases detected in the military who applied for help were pain in trigeminal neuropathy and myalgia of the face. The military associated the occurrence of existing pain symptoms in the oral cavity (89.12%) with previously carried out dental interventions in the oral cavity.
Conclusions. A statistically significant relationship between the late turnover of military serving in the Far North and the chronicity of all forms of oral pain syndromes was found.
FEATURES OF DENTAL STATUS IN PATIENTS WITH CANCER
Authors: Успенская Ольга , Uspenskaya Ol'ga , Фадеева Ирина , Fadeeva Irina 
Published: May 2019

Subject. In the modern world, the prevalence of cancer is growing every year, in this regard, this pathology is one of the most pressing problems in medicine. There is no doubt that malignant neoplasms have a complex interaction with the body. The General mechanisms of occurrence and progression of the tumor process are intensively studied, and to date, a huge amount of material on molecular and clinical Oncology has been accumulated, it is used in related disciplines.
The most important sections of dentistry are the diagnosis and treatment of diseases of the mucous membrane. Often, clinical manifestations in the oral cavity are one of the first symptoms indicating a General somatic disease. This article covers the study of the dental status of patients with different localizations of cancer.
Objective ― to study the incidence of dental diseases of patients with cancer.
Methodology. To conduct a study medical examination of patients with different localizations of cancer was held to determine dental: the definition of DMF-Index, PMA-index, Parodontal Index, and the condition of the mucous membrane of the oral cavity and periodontal tissues. Cancer patients receiving chemotherapy and radiation therapy, patients who refused to participate in the survey were excluded from the survey.
Results. The study included 526 patients. The predominance of certain types of dental diseases among patients with a particular cancer pathology was revealed.
Conclusions. Our study showed that all patients had decompensated forms of caries. The most common dental diseases combined with cancer are hyperplasia filiform papillae (K14.3), the "geographic" language (K14.1). Periodontal disease occurred in 69,5 % of cases among cancer patients.
LOCAL TREATMENT OF PURULENT WOUNDS AT PURULENT-INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION IN CHILDREN
Authors: Чуйкин Сергей , CHUYKIN Sergey , Хасанов Тимур , KXASANOV Timur , Шикова Юлия , SHIKOVA Iuliia , Макушева Наталья , Makusheva Natal'ya , Изосимов Артем , IZOSIMOV Artem , Викторов Сергей , Victorov Sergey , Рахмангулов Рустам , Rahmangulov Rustam 
Published: May 2019

Importance ― optimization of local treatment of purulent wounds in inflammatory diseases of the maxillofacial area in children.
Objectives ― improving the effectiveness of local treatment of children with purulent-inflammatory diseases of the maxillofacial area.
Methods. The study included 74 children who were treated for abscesses and phlegmon of the maxillofacial area in the Republican Clinical Hospital of Ufa. The patients were divided into 2 groups. The main group included 34 children with abscesses and phlegmon of the maxillofacial area. For treatment they used ointment with Furacilin, Lidocaine and Dibunolum. The control group included 40 patients. For their treatment used ointment Levomecol.
Results. The course of the wound process in patients of both groups was accompanied by edema in the postoperative wound area. Edema was stopped 1.2 times faster in the main group (p<0,01). In the main group, hyperemia persisted for up to 3 days. In the control group, hyperemia persisted at 3.9 ± 0.2 days. Normalization of temperature after surgery in the main group occurred one day earlier (at 4,3±0,8 day). Reduced pain in children in the main group was observed after 3 days. Normalization of blood counts in the main group was faster. The healing of the postoperative wound in the main group occurred by 7.7 ± 0.2 days, in the control group – at 8.8 ± 0.2 days (p<0,01). The dynamics of the wound process in the main group was faster.
Conclusions. Thus, the ointment based on Furacilin, Lidocaine and Dibunolum provides a prolonged effect of drugs, prevents side effects, creates a high concentration of the drug in the short term, possesses osmotic activity, improves the drainage conditions of the wound, leads to anti-inflammatory, antimicrobial, anesthetic action. The ointment is convenient and hygienic to use.
Microencapsulation of Lactobacillus acidophilus with Freeze Drying Method and Application to Synbiotic Beverage of Banana Corm Stone
Authors: Sumanti Debby Moody , Hanidah In in , Kayaputri Indira Lanti , Rialita Tita , Sukarminah Een , Zakaria Raisha Audina Prameswari 
Published: May 2019

Functional foods preferred currently should contain both prebiotics like inulin and frukto-0ligosaccharide and probiotics as Lactobacillus acidophilus required for good health. Functional food in the form of the synbiotic beverage can be made using banana corm stone which acts as prebiotic and has phenolic, tannin, and antioxidant with the addition of Lactobacillus acidophilus microcapsules roling as probiotic. Probiotics are bacteria can contribute to improving health, especially in the digestive system, one of the probiotic bacteria are beneficial to health is the Lactobacillus acidophilus . The number of probiotic bacteria that must be consumed to get the benefits that â‰¥107 CFU/g, so that the viability needs to be maintained. This study aimed to determine the cell viability of L.acidophilus microcapsules and define the effect of Lactobacillus. acidophilus microcapsules concentration on microbiological quality and sensory of synbiotic beverage from banana corm stone. The study was conducted using randomized block design (RBD) with five concentrations treatment namely 2%, 4%, 6%, 8%, and 10% (w/v) repeated 3 times. The results showed that the Lactobacillus. acidophilus microcapsules bacteria produced had a white color and fine crystalline powder form with a size of 2.2 Î¼m, the yield of 18.62% and cell viability of probiotic bacteria L. acidophilus 93.47%. The addition of Lactobacillus. acidophilus microcapsules as much as 8% produced the best synbiotic beverage of banana corm stone with following characteristics: total probiotic bacteria 10.4 Log CFU/ml, pH 7.33, panellist preference values of color, aroma, taste and viscosity of synbiotic beverage of banana corm stone were like slightly to like.
Synthesis and study of the antimicrobial activity of nifuroxazide derivatives
Authors: Sidorov Nikita G. , Kravchenko Alexey D. , Poddubikov Alexander V. , Arzumanian Vera G. 
Published: May 2019

ABSTRACT
The number of infections caused by microorganisms that are resistant to antibiotics and synthetic antibacterial drugs is growing fast worldwide. This is one of the most important and urgent problems in health care. The main efforts of researchers around the world are focused on solving this issue. Nitrofurans represent one of the most effective classes of antibacterial drugs. We have synthesized 4 analogues of nifuroxazide – a well known nitrofuran antibiotic – and confirmed their structures by NMR, IR spectroscopy, and mass-spectrometry. All of the obtained compounds were studied for antimicrobial and antifungal activity.
Activity against Escherichia coli, Staphylococcus aureus, Staphylococcus haemolyticus, and Pseudomonas aeruginosa was evaluated by the agar diffusion method. The synthesized compounds suppressed the growth of all the studied bacterial strains except Escherichia coli; the diameter of the inhibition zones ranged from 13.5 to 28 mm depending on the concentration of the tested compound and bacterial strain. One of the compounds studied in this project – the pyridine analogue of nifuroxazide – exceeded the activity of the standard (nifuroxazide) against the Staphylococcus aureus. The inhibitory activity of the synthesized compounds against the Candida albicans and Cryptococcus neoformans yeasts was determined using the microdilution method. The results were assessed according to the indicator color change. None of the studied compounds showed activity against these cultures.
The obtained results confirm that substituted nifuroxazides have significant antimicrobial activity and, therefore, can be considered as promising candidates for developing new antibacterial drugs.
A retrospective study of influenza rapid antigen test positivity with drug prescribing and clinical symptoms
Authors: BAYIRLI TURAN Derya , GÜMÜŞ Defne , KALAYCI YÜKSEK Fatma , KURUOĞLU Tuba , PAMUKCU Ayça , ŞEREFHANOĞLU Kıvanç 
Published: May 2019

Aim:Influenza
like illnesses (ILI) are the most prevalent reason for unnecessary antibiotic
prescribing. Our aim was to evaluate the rapid antigen test(RAT)positivity with
drug prescribing and clinical symptoms for ILI which is also a first report for
Turkey.Material and Methods:From September 2015 to June 2017, 1200 patients with ILI were included
in this study. Nasopharyngeal swabs were taken from all enrolled patients.
Antigen test was used for rapid detection of Influenza A/B virus, and the
results were compared with clinical manifestations and drug prescriptions. Results:RAT
results were positive in 414 (34.5%) of 1200 patients. Fever (984
patients/82%), cough (727 patients/60.6%) and weakness (270 patients/22.5%)
were common complaints. 371 (89.6%) out of 414 RAT positive patients had fever
(p&lt;0.01). 174 (42%) out of 414 RAT positive patients were medicated with antivirals
(p&lt;0.01). In addition, 516 (65.6%) out of 786 RAT negative patients were
medicated with only antibacterial (p&lt;0.01).

Conclusion:Our results supported a positive RAT test has an improving effect on the
unnecessary antibiotic prescribing. However, in Turkey the prevalence of
antibiotic prescription rates are still very high. Therefore we suggest that,
RAT can be used effectively to reduce antibiotic usage when a quick decision is
necessary.
The effects of insulin and glucose on growth and expression of mar regulon in E. coli
Authors: GÜMÜŞ Defne , KALAYCI YÜKSEK Fatma , UZ Gülşen , BAYRAKTAR Aslı , KÖSEOĞLU Pınar , OFLUOĞLU Yağmur , DAYLAN Benay , ANĞ KÜÇÜKER Mine 
Published: May 2019

Aim:Host factors
are known to modulate virulence, antibiotic susceptibility and growth of
bacteria. In the present study we aimed to investigate the effect of human
insulin and glucose on growth and expression of mar regulon (marA, marR, ompF, acrA, acrB and tolC) of E. coli SPC105. Material and Methods:E. coli SPC105 was
grown in tryptic soy broth (TSB-control) and TSB containing 20 µU/mL insulin,
200 µU/mL insulin, 0.1% glucose and 200 µU/mL insulin + 0.1% glucose. Growths
were determined via turbidimetric method.
Quantitative polymerase chain reaction (qPCR) was used to determine the
gene expression levels. Statistical analysis were performed via Tukey’s post
hoc-test. Results:According to
absorbance values, it has been shown that 0.1% glucose and 200 µU/mL insulin +
0.1% glucose have led a significant decrease on growth. Expression of acrA gene was shown to be decreased in
the presence of 200μIU insulin. Expressions of marR and marA were also
decreased in 200μU insulin, 0.1 % glucose+200μU insulin and 0.1% glucose added
TSB. Decreasing of marA, marR and acrA expressions were shown to be statistically significant
(p&lt;0.05).

Conclusion:The results
of the present study has shown once more that host factors may influence the
growth of a bacterium as well as gene expressions associated with antibiotic
susceptibilities.
Persecución Sobre Clio. Cuando El presentismo neoliberal alcanzó a las humanidades
Authors: Martínez Moya Armando 
Published: May 2019

En las últimas décadas, producto de los acelerados procesos de modernización industrial, comercial y de la comunicación, han empezado a cimbrase diferentes pilares que habían sostenido secularmente a las sociedades modernas. Estos vertiginosos cambios se hacen aún más drásticos cuando impactan en las sociedades en desarrollo, puesto que sus mecanismos de estabilización y fortaleza estructural son precarios, desiguales y débiles.
Partiendo de la situación del panorama latinoamericano, estos impactos se hacen sentir también en la educación superior, sobre todo en la enseñanza de las ciencias sociales, otrora eslabón fortalecedor para el análisis e interpretación de los fenómenos humanos, particularmente la historia, como recurso de conciencia y el tiempo. Pero no solo ella ha resentido los embates silenciosos y discretos pero a la vez contundentes y crudos de una modernidad disciplinar presentista que ha venido desplazando y refuncionalizando los currículos, las profesiones, así como los espacios y sobre todo los paradigmas de las ciencias sociales y de las humanidades, a efecto de ir insertando disciplinas del campo de las ciencias naturales, exactas y administrativas, convirtiéndolas en alternativas y propósitos unívocos para darle mayor énfasis a la formación universitaria contemporánea.
El presente texto aborda el problema de las universidades, tomando como referencia a México y en particular a la Universidad de Guadalajara. Se parte de una mirada panorámica de cómo se fueron forjando las humanidades, tomando como parangón la disciplina de la historia y a quienes fueron sus primeros profesores y profesoras. Se desbroza históricamente la trayectoria difícil y cuesta arriba de la construcción de sus paradigmas hasta que los esfuerzos docentes y de investigación permitieron su profesionalización y legitimación en las universidades mexicanas.
Sin embargo, en los últimos 25 años, aproximadamente de manera vertiginosa y multifactorial, se fueron implementando políticas de acotamiento para reorientar presupuestos, programas, escuelas y modelos acordes con los nuevos paradigmas que se sustentan en un neoliberalismo académico que tiene como consigna, la productividad, la rentabilidad, la eficiencia y por lo tanto la formación de cuadros destinados a esos fines. Este asunto ha afectado a las ciencias sociales. Aquí se hace un breve recuento de los que efectos han repercutido en muchos ámbitos respecto a usuarios, currículos y carreras. El método de exposición de este ensayo se sustenta en un recuento de evidencias y experiencias documentales y bibliográficas tanto de la trayectoria y construcción humanística, como de las influencias e implicaciones del modelo presentista neoliberal.
El método de exposición de este ensayo se sustenta en un recuento de evidencias y experiencias documentales y bibliográficas tanto de la trayectoria y construcción humanística, como de las influencias e implicaciones del modelo presentista neoliberal.
Construções mentais e distanciamento psicológico: um estudo bibliométrico
Authors: Vils Leonardo , Freire Otávio Bandeira De Lamônica , Mazieri Marcos Rogério , Rodrigues Gustavo Viegas 
Published: May 2019

Vivemos o aqui e o agora. O que passou ou acontecerá e o que está distante física, temporal ou socialmente exige que transcendamos o aqui e o agora de maneira a imaginarmos, concebermos ou representarmos aquilo que não é próximo. Da mesma maneira que ao nos afastarmos fisicamente de um objeto perdermos o foco nos detalhes e começamos a notar suas características gerais, o distanciamento psicológico em relação a eventos, pessoas, objetos, localidades e possibilidades muda nossa visão a seu respeito. As distintas representações mentais de eventos próximos e distantes são o foco da Construal Level Theory (CLT). Analisamos, por meio de um estudo bibliométrico, o desenvolvimento da CLT em dois períodos, buscando identificar as origens de teoria, seus desdobramentos e eventual desvinculação de autores e teorias seminais que suportaram o seu desenvolvimento. Os resultados da análise fatorial exploratória das citações nos dois períodos estudados indicam que a CLT se desvincula das teorias seminais que a fundamentaram ganhando corpo teórico próprio.
CORPORATE SOCIAL RESPONSIBILITY OF DJARUM FOUNDATION IN PREPARING INDONESIAN FUTURE LEADERS
Authors: Tati Firma Friskila , Wijaya Lina Sinatra 
Published: May 2019

The progress of a country cannot be separated from the existence of human resources, but to achieve a developed country, requires the productive, creative, and innovative human resources in managing the resources in Indonesia. To create the productive human resources, the role of the government and private sectors is needed for the progress of Indonesia. Through Djarum Foundation, PT. Djarum does the Corporate Social Responsibility (CSR), one of the CSR program is giving the scholarship (Djarum Scholarship Plus) to the college student which aims to create the future leaders. The aim of this research is to find out how CSR of Djarum Foundation in preparing Indonesian future leaders and what soft skill training programs can enhance the character of leadership in character building. This research is a descriptive qualitative research which uses interview for gaining the data, the target of this research is the representative of Djarum Scholarship Plus grantees of 28th-32nd generation. The result of this study showed that in preparing and creating the Indonesian future leaders, Djarum Foundation through CSR actively conducted the soft skill training programs (Character Building, Leadership Development, and Nation Building) and the implementation programs (Community Empowerment, Competition Challenge, and International Exposure) to bring about good changes for the progress of Indonesia.Keywords: corporate social responsibility, djarum foundation, leadership, soft skill