bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data
Authors: Cairns Jonathan , Orchard William R. , Malysheva Valeriya , Spivakov Mikhail 
Published: January 2019

AbstractSummaryCapture Hi-C is a powerful approach for detecting chromosomal interactions involving, at least on one end, DNA regions of interest, such as gene promoters. We present Chicdiff, an R package for robust detection of differential interactions in Capture Hi-C data. ChiScdiff enhances a state-of-the-art differential testing approach for count data with bespoke normalisation and multiple testing procedures that account for specific statistical properties of Capture Hi-C. We validate Chicdiff on published Promoter Capture Hi-C data in human Monocytes and CD4+ T cells, identifying multitudes of cell type-specific interactions, and confirming the overall positive association between promoter interactions and gene expression. Chicdiff is implemented as an R package that is publicly available at https://github.com/RegulatoryGenomicsGroup/chicdiff.
Mechanosensitive nuclear asymmetries define a bipolar spindle scaffold to ensure mitotic fidelity
Authors: Nunes Vanessa , Dantas Margarida , Castro Domingos , Vitiello Elisa , Wang Irène , Carpi Nicolas , Balland Martial , Piel Matthieu , Aguiar Paulo , Maiato Helder , Ferreira Jorge G. 
Published: January 2019

AbstractDuring prophase, centrosomes need to separate and position to correctly assemble the mitotic spindle. This process occurs through the action of molecular motors, cytoskeletal networks and the nucleus. How the combined activity of these different components is spatiotemporally regulated to ensure efficient spindle assembly remains unclear. Here we show that during prophase the centrosomes-nucleus axis reorients, so that centrosomes are positioned on the shortest nuclear axis at nuclear envelope (NE) breakdown. This centrosomes-nucleus configuration depends on mechanical cues generated by mitotic chromosome condensation on the prophase nucleus. We further show these mechanosensitive cues act through SUN1/2 and NudE+NudEL to enable the polarized loading of Dynein on the NE. Finally, we observe this centrosome configuration favors the establishment of an initial bipolar spindle scaffold, facilitating chromosome capture and accurate segregation, without compromising division plane orientation. We propose that chromosome segregation fidelity depends on the mechanical properties of the prophase nucleus that facilitate spindle assembly by regulating NE-Dynein localization.
Organizational learning and benchmarking in university technology courses
Authors: Rübenich Nilson Varella , Dorion Eric Charles Henri , Eberle Luciene 
Published: January 2019

PurposeThe purpose of this paper is to analyze the management practices that contribute to single and double cycles of organizational learning in the vocational education of the Brazilian higher education technology courses (HETC), and to study the learning outcomes that result through the Brazilian Ministry of Education SINAES indicators.Design/methodology/approachIt consisted in both participant observation and quantitative phases. The participant observation phase included a benchmarking activity at École de Technologie Supérieure (ÉTS) de Montréal, to analyze and delimitate their practices for the preparation of the second phase, test the hypotheses by means of modeling of structural equations.FindingsThe key practices that contribute to organizational learning in the Brazilian HETC were identified through a benchmark activity at ÉTS by using a quantitative research scheme of single cycles of organizational learning, and further in correspondence with the Brazilian criteria (SINAES-Ministry of Education).Research limitations/implicationsThe extent of the sample is concentrated in the southern region of Brazil (Rio Grande do Sul, Santa Catarina and Paraná), limiting its representativeness to a regional basis.Practical implicationsPractices that contribute to organizational learning are a counterpoint and a complement of the Brazilian Ministry of Education SINAES indicators, which value the formalization of those courses and the future actions in the Brazilian universities.Social implicationsThe study re-inforces the importance of organizational learning for the development of excellence in Brazilian HETC.Originality/valueThe results contribute to build analysis frameworks on the relationships between management practices, organizational learning, benchmarking and organizational outcomes, particularly in the management of the technology courses and for Brazilian universities.
Using integrated weighted IRP-Fuzzy TISM approach towards evaluation of initiatives to harmonise Halal standards
Authors: Khan Mohd Imran , Khan Shahbaz , Haleem Abid 
Published: January 2019

Purpose
Multiplicity and conflicting Halal standards involve unnecessary repetition of testing for demonstrating the Halal integrity of the process and the product, thus making it difficult for the Halal commodities to get traction in international markets. The purpose of this paper is to suggest initiatives to facilitate harmonisation of Halal standards as to eliminate trade barrier of Halal and to assure the availability of Halal consumables to larger masses.

Design/methodology/approach
Ranking of the initiatives for the harmonisation of Halal standards taking in consideration the costs of accomplishment and associated benefits obtained has been done through the application of integrated Interpretive Ranking Process (IRP) and Fuzzy Total Interpretive Structural Modelling (Fuzzy TISM). This integrated methodology with the weighted criteria have refined the value of the net dominance of different variables, thereby increasing the efficacy of IRP in decision making.

Findings
Findings suggest that strengthening the strategic coordination and collaboration among competent HCBs is a significant initiative. This initiative needs to be undertaken to mitigate the conflict between HCBs. This necessitates to develop a common platform in making the collective decision for effectively controlling Halal businesses. Moreover, recognising competent HCBs will prompt the effective implementation and execution of Halal standards across the supply chain, and ease the global trading of Halal products. A framework has been conceptualised to enable harmonisation of Halal standards which intimates to develop globally agreed protocols for Halal practices.

Practical implications
The framework presented may act as a prelude to harmonise Halal standards and may positively affect the international trade of Halal commodities by phasing out the discriminatory and market-impeding standards.

Originality/value
A harmonised system may provide correct information to the stakeholders and may help in making an informed decision.
Developing the business-society nexus through corporate responsibility expectations in India
Authors: Bergman Zinette , Teschemacher Yael , Arora Bimal , Sengupta Rijit , Leisinger Klaus Michael , Bergman Manfred Max 
Published: January 2019

PurposeThe Government of India dramatically altered the dynamic between business and society when it introduced the Companies Act 2013, which mandated firms to expend at least 2 per cent of average net profits on corporate responsibility (CR) programmes. This reconfiguration of social value creation may serve as a template for a closer and participatory relationship between the private sector and government in emerging economies and beyond. This paper aims to analyse how CR expectations have taken shape in the print media in India. Specifically, the authors ask the following: What are the dimensions of CR expectations in mainstream Indian newspapers?, and Why, according to the newspaper narratives, do corporations have these responsibilities?Design/methodology/approachIn this qualitative study, the authors randomly selected and analysed 50 per cent (n= 442) of the newspaper articles that dealt explicitly with CR. The articles appeared in the top five Indian English-language newspapers and the top two Hindi-language newspapers between 1 January and 31 December 2015. Using Content Configuration Analysis (CCA), the authors developed a typology of CR expectations and analysed their associated justifications. Finally, they used CCA to analyse how this typology and its justifications connect to the two main stakeholders: the business sector and government.FindingsThe analyses reveal how the introduction of the Companies Act 2013 had a major impact on CR expectations by explicitly and legally casting the business sector as the engine of social development. The authors were able to describe how contextual and cultural dimensions frame evolving interests and societal demands towards corporations, and how difficult it may be for corporations to fulfil CR expectations that are well beyond their core business and that reach domains usually pertaining to government.Originality/valueThis study contributes an empirical exploration of media discourse on contemporary CR expectations in India and its associated notions of social value creation, and how these are shaped by various cultural and contextual influences. The authors discuss how this novel approach to CR modifies the relations between business and society, and they reflect on the opportunities and limits of this model for other emerging economies, which struggle to formulate a symbiotic relationship between business and society.
Reproducing kernel mesh-free collocation analysis of structural vibrations
Authors: Qi Dongliang , Wang Dongdong , Deng Like , Xu Xiaolan , Wu Cheng-Tang 
Published: January 2019

PurposeAlthough high-order smooth reproducing kernel mesh-free approximation enables the analysis of structural vibrations in an efficient collocation formulation, there is still a lack of systematic theoretical accuracy assessment for such approach. The purpose of this paper is to present a detailed accuracy analysis for the reproducing kernel mesh-free collocation method regarding structural vibrations.Design/methodology/approachBoth second-order problems such as one-dimensional (1D) rod and two-dimensional (2D) membrane and fourth-order problems such as Euler–Bernoulli beam and Kirchhoff plate are considered. Staring from a generic equation of motion deduced from the reproducing kernel mesh-free collocation method, a frequency error measure is rationally attained through properly introducing the consistency conditions of reproducing kernel mesh-free shape functions.FindingsThis paper reveals that for the second-order structural vibration problems, the frequency accuracy orders arepand (p− 1) for even and odd degree basis functions; for the fourth-order structural vibration problems, the frequency accuracy orders are (p− 2) and (p− 3) for even and odd degree basis functions, respectively, wherepdenotes the degree of the basis function used in mesh-free approximation.Originality/valueA frequency accuracy estimation is achieved for the reproducing kernel mesh-free collocation analysis of structural vibrations, which can effectively underpin the practical applications of this method.
Exploring doctoral students’ expectations of work-based skills training
Authors: Candy Jenny , Rodrigo Padmali , Turnbull Sarah 
Published: January 2019

Purpose
Doctoral students are expected to undertake work-based skills training within their doctoral studies in areas such as problem solving, leadership and team working. The purpose of this paper is to explore student expectations of doctoral training within a UK Higher Education context.

Design/methodology/approach
The data for the study were gathered via two focus groups conducted among doctoral students from different faculties in a post-92 UK University. Participants were selected using a snowball sampling approach.

Findings
The findings suggest that the expectations of doctoral students are contingent upon their year of study, study mode, perceived fit between training goals and available training, peer recommendations, word-of-mouth (WoM) and the scholarly support they received from their supervisors.

Practical implications
The study suggests a better understanding of students’ segmentation can help Higher Education Institutions deliver training that meets the expectations of doctoral students in a way that result in zero or a positive disconfirmation.

Originality/value
This paper develops and deepens the understanding of the doctoral students’ expectations of work-based skills training and highlights the need for universities to adapt their doctoral training according to the expectations of different student segments.
Developing generic skills at an Islamic higher education institution curriculum in Aceh, Indonesia
Authors: Muluk Safrul , Habiburrahim Habiburrahim , Zulfikar Teuku , Orrell Janice , Mujiburrahman Mujiburrahman 
Published: January 2019

PurposeThe purpose of this paper is to identify skills and attributes that should be included in developing curricula, especially in the area of education. In this case, English Education Department of Ar-Raniry State Islamic University, Banda Aceh, is in charge of the preparation of English language teachers and English language professionals exceeding required standards and be competitive in the labour market.Design/methodology/approachThis qualitative research involved 38 research participants consisting of government authorities, academics and students. Interviews and focus group discussions were employed to collect the data. Both interview and FGD results were analysed through thematic analysis.FindingsThe findings indicate that among the generic skills that need to be incorporated into the department curriculum in order to improve graduates’ quality and meet the requirements of the labour market are: information and communication technology (ICT), leadership, religious competencies, entrepreneurship and communication skills.Originality/valueThe paper has been developed through research conducted by the authors. Therefore, the authors confirm that the paper has been written according to the academic standard and is free from plagiarism.
How cultural values are reflected on the housing market – direct effects and the cultural spillover
Authors: Andersson Magnus , Kopsch Fredrik , Palm Peter 
Published: January 2019

Purpose
The purpose of this paper is to analyse two questions. First, is there, and if so, how large is the price premium paid for a building exhibiting a cultural value? Second, are there any spillover effects of buildings with cultural values on sales prices of neighbouring houses?

Design/methodology/approach
Using a unique database of all buildings in the region of Halland, Sweden, combined with transaction data, hedonic models can be estimated, with spatially lagged variables describing proximity to three classes of culturally classified building – A, B and C – corresponding to building of national interest, building of regional interest and building of local interest. In addition, the authors also estimate models with a spatial specification on the error term, in an attempt to control for omitted variables.

Findings
The results indicate that cultural classification plays a role in determining the price of a property, with large effects (ranging between 36 and 60% price premiums) for the highest classification. In addition, the authors find evidence of a cultural externality, houses in the vicinity of building with high cultural value sell at a small, but statistically significant premium of 1%.

Originality/value
The cultural externality may be overlooked when it comes to valuation of cultural values in society, and therefore, it is likely that warranted protection acts to preserve cultural values in buildings become less than the social optimum. This paper suggests a new measure to cultural values contrasting previous research that rely on cultural preservation. This approach should limit problems with measurement errors that may lead to biased results.
Is data privacy a fundamental right in India?
Authors: Chatterjee Sheshadri 
Published: January 2019

Purpose
The purpose of this study is to identify how the privacy policy can be framed for protection of personal data and how the latest judgement of full bench of Supreme Court of India has dealt with right to privacy in India.

Design/methodology/approach
The study uses the latest Supreme Court judgement on right to privacy and historical cases on right to privacy in India. This paper uses Indian Constitution as a source of Information for study along with case laws and judgements of different courts in India.

Findings
This paper tries to find if personal data privacy is a fundamental right in India. In addition, the paper provides recommendations to different concerned authorities on protecting personal information in online platform.

Research limitations/implications
This study deals with privacy issues so far as Indian citizens are concerns and does not focus on other countries. Moreover, the study tries to understand the issue of fundamental rights from Indian Constitution perspective. In addition, the recommendations provided to the policymakers and other authorities of India have wide implications for formulation of new policy and management of personal data, so that it should not go to wrong hands and the personal data and privacy is protected of the citizens.

Practical implications
Millions of people put their personal information in online platform. In addition, there are few government initiatives in India such as Aadhaar card where the biometric information is taken from the residents of India, and in many cases, the personal data are compromised under various circumstances. As the personal data of the citizens are in question, thus the study has direct practical implication mainly for all the citizens whose personal data are available in online platform.

Social implications
This study has social implication as it dealt with the “personal data” of the citizens of India. As the paper discusses the issue of protection of personal data in the context of right to privacy, thus this study has a direct social impact so far as online citizen of India is concerned.

Originality/value
This paper is timely, original and discusses the contemporary issue of online data privacy and fundamental right in India. This paper is a useful resource for the researchers, policymakers and online users who deal with personal data-, right to privacy and data privacy policy-related areas.
The effect of audit committee attributes on compliance with IAS 24-related party disclosure
Authors: Agyei-Mensah Ben Kwame 
Published: January 2019

PurposeThis paper aims to investigate the compliance with IAS 24 and possible audit committee attributes that can influence companies in Ghana to disclose related party (RP) information in their annual reports.Design/methodology/approachDifferent univariate tests and multivariate regressions have been used to examine the hypotheses. The sample includes 120 firm-year observations for the period 2013-2016.FindingsThe findings of the paper reveal that related party disclosure compliance is influenced by audit committee gender, audit committee independence and ownership concentration.Originality/valueTo the best of the author’s knowledge, there are no empirical studies that have addressed the effect of audit committee attributes on IAS 24 in Ghana and the second of such study in sub-Saharan Africa.
Modelling of wear debris in planetary gear drive
Authors: Ranjan Rakesh , Ghosh Subrata Kumar , Kumar Manoj 
Published: January 2019

Purpose
The probability distribution of major length and aspect ratio (major length/minor length) of wear debris collected from gear oil used in planetary gear drive were analysed and modelled. The paper aims to find an appropriate probability distribution model to forecast the kind of wear particles at different running hour of the machine.

Design/methodology/approach
Used gear oil of the planetary gear box of a slab caster was drained out and charged with a fresh oil of grade (EP-460). Six chronological oil samples were collected at different time interval between 480 and 1,992 h of machine running. The oil samples were filtered to separate wear particles, and microscopic study of wear debris was carried out at 100X magnification. Statistical modelling of wear debris distribution was done using Weibull and exponential probability distribution model. A comparison was studied among actual, Weibull and exponential probability distribution of major length and aspect ratio of wear particles.

Findings
Distribution of major length of wear particle was found to be closer to the exponential probability density function, whereas Weibull probability density function fitted better to distribution of aspect ratio of wear particle.

Originality/value
The potential of the developed model can be used to analyse the distribution of major length and aspect ratio of wear debris present in planetary gear box of slab caster machine.
Customer service communication with customers with disability
Authors: Taylor Susan Elizabeth , Balandin Susan , Wilson Erin , Murfitt Kevin 
Published: January 2019

PurposeThe purpose of this paper is to review published research on retail customer service communication with people with complex communication needs (CCN) and impacts on their social inclusion.Design/methodology/approachThe researchers searched electronic databases EBSCOHost and Web of Science and found no studies on retail customers with CCN. The search was expanded with the intention of exploring factors affecting people with disability as a group and to locate the experience of people with CCN within findings. Studies found were reviewed by the first author and two external reviewers.FindingsTwelve articles met the broadened inclusion criteria. Analysis using the International Classification of Functioning, Disability and Health (ICF) found the literature demonstrated some environmental and personal factors that are likely to construct disability in the retail environment for people with CCN. The authors proposed further research to further explore ICF factors not identified in research and to establish links with social inclusion.Research limitations/implicationsFurther research is needed to understand the role of retail customer service communication in the social inclusion of people with CCN.Social implicationsThe social inclusion of people with CCN will be assisted by findings on good practice customer service communication.Originality/valueShopping is rarely considered in social inclusion research. This review discovered an absence of research into the impact of retail customer communication on inclusion of customers with CCN and proposed a framework for further enquiry.