bluuebunny/crossref_metadata_2025_split huggingface dataset:
ORCHIDEE-ROUTING: revising the river routing scheme using a high-resolution hydrological database
Authors: Nguyen-Quang Trung , Polcher Jan , Ducharne Agnès , Arsouze Thomas , Zhou Xudong , Schneider Ana , Fita Lluís 
Published: December 2018

Abstract. The river routing scheme (RRS) in the Organising Carbon and Hydrology in Dynamic Ecosystems (ORCHIDEE)
land surface model is a valuable tool for closing the water cycle in a
coupled environment and for validating the model performance. This study
presents a revision of the RRS of the ORCHIDEE model that aims to benefit
from the high-resolution topography provided by the Hydrological data and
maps based on SHuttle Elevation Derivatives at multiple Scales (HydroSHEDS),
which is processed to a resolution of approximately 1 km. Adapting a new
algorithm to construct river networks, the new RRS in ORCHIDEE allows for the
preservation of as much of the hydrological information from HydroSHEDS as
the user requires. The evaluation focuses on 12 rivers of contrasting size
and climate which contribute freshwater to the Mediterranean Sea. First, the
numerical aspect of the new RRS is investigated, in order to identify the
practical configuration offering the best trade-off between computational
cost and simulation quality for ensuing validations. Second, the performance
of the new scheme is evaluated against observations at both monthly and daily
timescales. The new RRS satisfactorily captures the seasonal variability of
river discharge, although important biases stem from the water budget
simulated by the ORCHIDEE model. The results highlight that realistic
streamflow simulations require accurate precipitation forcing data and a
precise river catchment description over a wide range of scales, as permitted
by the new RRS. Detailed analyses at the daily timescale show the promising
performance of this high-resolution RRS with respect to replicating river
flow variation at various frequencies. Furthermore, this RRS may also
eventually be well adapted for further developments in the ORCHIDEE land
surface model to assess anthropogenic impacts on river processes (e.g.
damming for irrigation operation).
Something visible in Japanese
Authors: Hiraiwa Ken 
Published: December 2018

A number of languages of the world show a striking change in word order when what is modified is an indefinite pronoun: the modifier necessarily appears postnominally (e.g. something visible vs. *visible something). English and French are examples of this ordering pattern. Japanese, a head-final language with exclusively prenominal modifiers, nevertheless exhibits the same order as English and French when indeterminate phrases (indefinite pronouns) are modified. I argue that although the modifier in such structures may appear to be a postnominal modifier of the preceding indeterminate phrase, it is actually a prenominal modifier of the following light noun n. I further propose that the English/French-type construction has the same underlying structure as the Japanese-type construction and that apparent differences follow from a difference in the composition of so-called indefinite pronouns: an indeterminate system versus a light-noun system.
The Complexity of Verbal Semantics—An Intricate Relationship Between Qatal and Wayyiqtol
Authors: Andrason Alexander 
Published: December 2018

This article analyzes the relationship that exists between the qatal and wayyiqtol forms in Biblical Hebrew. It provides a twofold approach, based on complexity theory, fuzziology, cognitive linguistics and the theory of dynamic semantic maps, on the one hand, as well as on an original empirical study involving all the instances of the two grams in the book of Genesis, on the other. As a result, the article advances a model of an intricate, multi-level and dynamic interaction of qatal and wayyiqtol in terms of two kinetic waves that spread along a grammaticalization channel recursively used in the language—in this case, the resultative stream.
Des immigrants pour la cause : la logique nationaliste du discours de presse sur l’immigration francophone en Acadie
Authors: Violette Isabelle 
Published: December 2018

Cet article a pour objectif d’examiner les idéologies linguistiques qui sous-tendent et orientent le traitement discursif de l’immigration dans la presse acadienne récente (2000-2014). Alors qu’à l’heure actuelle l’immigration canalise des tensions politiques et exacerbe des conflits nationaux dans de nombreuses sociétés occidentales, elle bénéficie d’une représentation médiatique favorable en Acadie du Nouveau-Brunswick. Or seule l’immigration dite « francophone » est jugée désirable et bénéfique, ce qui suppose une forme de régulation des communautés et des populations impliquées dans le faitfrançais. La presse acadienne relaie principalement un discours militant sur l’immigration qui consiste à en faire une cause à défendre pour le bien commun. L’auteure montrera que l’immigration francophone a bonne presse puisqu’elle est conçue pour servir une idéologie nationaliste de la langue : parler français suppose une allégeance aux communautés acadiennes et un engagement envers l’avenir de celles-ci.
La restriction alimentaire et l’anorexie mentale sous l’angle des théories évolutionnistes
Authors: Labonté Thalie , Paquette Daniel 
Published: December 2018

Diverses disciplines se sont intéressées à l’anorexie mentale au cours des dernières décennies et ont proposé différents modèles pour l’expliquer. Celui qui domine actuellement, le modèle biopsychosocial, permet de comprendre comment ce problème se met en place au niveau proximal. Toutefois, une question perdure : existe-t-il une fonction biologique à ce trouble? Il s’agit de l’énigme que les chercheurs adoptant une perspective évolutionniste ont tenté de résoudre. Plusieurs hypothèses ont été proposées et celles-ci seront revues et critiquées dans le cadre de cet article. Ensuite, une hypothèse alternative, l’hypothèse de la compétition intrasexuelle pour le rang, sera présentée et visera à accroître la valeur explicative des modèles proposés. Il sera argumenté que la restriction alimentaire et les troubles qui en découlent sont des sous-produits de l’intensification de la compétition entre les femmes dans la culture occidentale moderne. Alors qu’il aurait autrefois été adaptatif pour les femmes de compétitionner avec leurs consoeurs dans le but de correspondre aux traits physiques et psychologiques jugés désirables dans leur culture, ce mécanisme serait devenu hors de contrôle dans une société dont les critères de beauté sont irréalistes, voire inatteignables, et dans laquelle la minceur est glorifiée. La perspective évolutionniste, bien que parfois méconnue, a le mérite d’amener un point de vue novateur qui stimule la réflexion théorique à un niveau d’analyse différent, mais complémentaire, à ce que proposent les approches conventionnelles.
Entre revendication et partenariat : la construction du mouvement de défense des droits des personnes handicapées au Québec entre 1975 et 1985*
Authors: Bourgault1 Gilles 
Published: December 2018

Au Québec, les décennies 1970 et 1980 constituent une période effervescente par rapport à l’élaboration et à la mise en place de lois et de politiques publiques concernant les personnes dites « handicapées ». Cet article vise à montrer qu’au travers les processus d’élaboration de lois et de politiques publiques concernant cette population, un mouvement structuré de promotion et de défense des droits des personnes handicapées s’est construit et qu’il a exercé son influence grâce, notamment, à une synergie singulière entre ce milieu associatif émergent et des décideurs politiques animés d’une apparente volonté de partenariat.
Actividad in vitro de Tedizolid y comparadores en aislamientos de Staphylococcus aureus resistentes a meticilina en infecciones de piel y tejidos blandos en 7 hospitales de Colombia
Authors: Leal Aura Lucía , Ovalle María Victoria , Cortés Jorge Alberto , Montañes Anita María , De la Rosa Zandra Rocío , Rodríguez José Yesid , Gualtero Sandra , Ariza Beatriz , Sussman Otto , Torres María Del Pilar 
Published: December 2018

Introducción. Staphylococcus aureus resistente a meticilina (SARM) causa infecciones severas de piel y tejidos blandos a nivel hospitalario y en los últimos años en la comunidad. Tedizolid, es una nueva oxazolidinona con potencia in vitro mayor que el linezolid frente a este tipo de microorganismo.Objetivo. Conocer la actividad antimicrobiana de tedizolid y antibióticos comparadores en aislamientos de SARM causante de infecciones de piel y tejidos blandos en hospitales de Colombia.Materiales y métodos. Estudio prospectivo, descriptivo multicéntrico, durante doce meses en 7 hospitales de tercer nivel de Colombia. Se colectaron aislamientos de SARM de pacientes adultos con infección de piel y tejidos blandos. Se determinó la concentración inhibitoria mínima (CIM) mediante la técnica de E-test (Biomerieux) a tedizolid, linezolid, vancomicina, daptomicina, trimetoprim sulfametoxazol y clindamicina.Resultados. Se obtuvieron aislamientos de SARM de 102 pacientes. De éstos, 56 (54,9%) fueron de género masculino y el promedio de edad fue de 46,8 años. La infección fue de inicio comunitario en 77 casos (75,4%). El tipo de muestra que predominó fue absceso en 69 pacientes (67,6%). Todos los aislamientos fueron sensibles a tedizolid, linezolid, daptomicina, trimetoprim sulfametoxazol y vancomicina. Tedizolid mostró mayor actividad in vitro que linezolid. Los intervalos de la CIM de tedizolid oscilaron entre 0,125 µg/mL a 0,5 µg/mL mientras que para linezolid estuvieron entre 1µg/mL y 2µg/mL.Conclusiones. Las cepas circulantes de SARM en Colombia presentan alta sensibilidad frente a tedizolid y se considera una alternativa terapéutica para las infecciones de piel y tejidos blandos en nuestro medio.
The commissioning and validation of Monaco treatment planning system on an Elekta VersaHD linear accelerator
Authors: Snyder Jeffrey E. , Hyer Daniel E. , Flynn Ryan T. , Boczkowski Amanda , Wang Dongxu 
Published: December 2018

AbstractAccurate beam modeling is essential to help ensure overall accuracy in the radiotherapy process. This study describes our experience with beam model validation of a Monaco treatment planning system on a Versa HD linear accelerator. Data were collected such that Monaco beam models could be generated using three algorithms: collapsed cone (CC) and photon Monte Carlo (MC) for photon beams, and electron Monte Carlo (eMC) for electron beams. Validations are performed on measured percent depth doses (PDDs) and profiles, for open‐field point‐doses in homogenous and heterogeneous media, and for obliquely incident electron beams. Gamma analysis is used to assess the agreement between calculation and measurement for intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans, including volumetric modulated arc therapy for stereotactic body radiation therapy (VMAT SBRT). For all relevant conditions, gamma index values below 1 are obtained when comparing Monaco calculated PDDs and profiles with measured data. Point‐doses in a water medium are found to be within 2% agreement of commissioning data in 99.5% and 98.6% of the points computed by MC and CC, respectively. All point‐dose calculations for the eMC algorithm in water are within 4% agreement of measurement, and 92% of measurements are within 3%. In heterogeneous media of air and cortical bone, both CC and MC yielded better than 3% agreement with ion chamber measurements. eMC yielded 3% agreement to measurement downstream of air with oblique beams of up to 27°, 5% agreement distal to bone, and within 4% agreement at extended source to surface distance (SSD) for all electron energies except 6 MeV. The 6‐MeV point of measurement is on a steep dose gradient which may impact the magnitude of discrepancy measured. The average gamma passing rate for IMRT/VMAT plans is 96.9% (±2.1%) and 98.0% (±1.9%) for VMAT SBRT when evaluated using 3%/2 mm criteria. Monaco beam models for the Versa HD linac were successfully commissioned for clinical use.
Catalytic and Electron Conducting Carbon Nanotube–Reinforced Lysozyme Crystals
Authors: Contreras‐Montoya Rafael , Escolano Guillermo , Roy Subhasish , Lopez‐Lopez Modesto T. , Delgado‐López Jose M. , Cuerva Juan M. , Díaz‐Mochón Juan J. , Ashkenasy Nurit , Gavira José A. , Álvarez de Cienfuegos Luis 
Published: December 2018

AbstractNovel reinforced cross‐linked lysozyme crystals containing homogeneous dispersions of single‐walled carbon nanotubes bundles (SWCNTs) are produced and characterized. The incorporation of SWCNTs inside lysozyme crystals gives rise to reinforced composite materials with tunable mechanical strength and electronic conductivity, while preserving the crystal quality and morphology. These reinforced crystals show increased catalytic activity at higher temperatures, being active even above the denaturation temperature. The electron transport through the crystals is linked to the content and distribution of SWCNT bundles inside the crystals. The electron conduction through the crystals is isotropic and very efficient, presenting high conductivity values up to 600 nS at very low (0.05 wt%) SWCNT concentration. To obtain these crystals, a new protocol based on the in situ crystallization of lysozyme in composite SWCNT–peptide hydrogels is developed. These peptide hydrogels are able to homogeneously disperse bundles of hydrophobic SWCNTs allowing first, the crystallization of the enzyme lysozyme and second, transferring the new properties of the inorganic component to the crystals. Taken together, these composite crystals represent an example of the versatility of proteins as biological substrates in the generation of novel functional materials, opening the door to use them in catalysis and bioelectronics at macroscale.
Stroke Recovery in Rats after 24‐Hour–Delayed Intramuscular Neurotrophin‐3 Infusion
Authors: Duricki Denise A. , Drndarski Svetlana , Bernanos Michel , Wood Tobias , Bosch Karen , Chen Qin , Shine H. David , Simmons Camilla , Williams Steven C. R. , McMahon Stephen B. , Begley David J. , Cash Diana , Moon Lawrence D. F. 
Published: December 2018

ObjectiveNeurotrophin‐3 (NT3) plays a key role in the development and function of locomotor circuits including descending serotonergic and corticospinal tract axons and afferents from muscle and skin. We have previously shown that gene therapy delivery of human NT3 into affected forelimb muscles improves sensorimotor recovery after stroke in adult and elderly rats. Here, to move toward the clinic, we tested the hypothesis that intramuscular infusion of NT3 protein could improve sensorimotor recovery after stroke.MethodsRats received unilateral ischemic stroke in sensorimotor cortex. To simulate a clinically feasible time to treatment, 24 hours later rats were randomized to receive NT3 or vehicle by infusion into affected triceps brachii for 4 weeks using implanted catheters and minipumps.ResultsRadiolabeled NT3 crossed from the bloodstream into the brain and spinal cord in rodents with or without strokes. NT3 increased the accuracy of forelimb placement during walking on a horizontal ladder and increased use of the affected arm for lateral support during rearing. NT3 also reversed sensory impairment of the affected wrist. Functional magnetic resonance imaging during stimulation of the affected wrist showed spontaneous recovery of peri‐infarct blood oxygenation level–dependent signal that NT3 did not further enhance. Rather, NT3 induced neuroplasticity of the spared corticospinal and serotonergic pathways.InterpretationOur results show that delayed, peripheral infusion of NT3 can improve sensorimotor function after ischemic stroke. Phase I and II clinical trials of NT3 (for constipation and neuropathy) have shown that peripheral high doses are safe and well tolerated, which paves the way for NT3 as a therapy for stroke. ANN NEUROL 2019;85:32–46.
Psychological analysis of consumer intertemporal decisions
Authors: Malkoc Selin A. , Zauberman Gal 
Published: December 2018

AbstractMany consumer decisions involve trade‐offs of benefits and costs distributed over time. Such decisions are often referred to as intertemporal decisions. The current review examines how the underlying psychological drivers of intertemporal preferences inform consumer decision‐making. To this end, we identify four important consumer decision domains—financial decision‐making, hedonic purchases, time management, and health decision‐making—and use the extensive work in intertemporal choice to inform these decisions and identify routes to understanding and improving consumer decision‐making.
Synthesis of Tetracoordinate Boron‐Fused Benzoaceanthrylene Analogs via Tandem Electrophilic C−H Borylation
Authors: Oda Susumu , Abe Hiroaki , Yasuda Nobuhiro , Hatakeyama Takuji 
Published: December 2018

AbstractBenzoaceanthrylene analogs with tetracoordinate boron at the ring junction were synthesized through tandem electrophilic C−H borylation of 2,6‐dinaphthylpyridine followed by nucleophilic substitution. Notably, the [5,6]‐annulation occurred selectively over [6,6]‐annulation with the assistance of nitrogen coordination of the pyridine ring. The X‐ray crystallographic analysis revealed the polycyclic skeleton with a distorted tetracoordinate boron atom and a unique packing structure with intermolecular π–π interaction. The photophysical and electrochemical properties of these benzoaceanthrylene analogs were evaluated by UV‐vis spectroscopy and differential pulse voltammetry. The electron affinity of the fluorine‐substituted derivative is estimated to be 3.49 eV from the ionization potential and optical band gap. Thus, this derivative is expected to be a promising n‐type semiconducting material.
Vanadium (III) Oxide/Carbon Core/Shell Hybrids as an Anode for Lithium‐Ion Batteries
Authors: Budak Öznil , Srimuk Pattarachai , Tolosa Aura , Fleischmann Simon , Lee Juhan , Hieke Stefan W. , Frank Anna , Scheu Christina , Presser Volker 
Published: December 2018

AbstractWe present a facile two‐step synthesis of vanadium (III) oxide/carbon core/shell hybrid material for application as lithium‐ion battery electrode. The first step is a thermal treatment of a mixture of vanadium carbide (VC) and NiCl2 ⋅ 6H2O at 700 °C in an inert gas atmosphere. Elemental nickel obtained from decomposing NiCl2 ⋅ 6H2O served as a catalyst to trigger the local formation of graphitic carbon. In a second step, residual nickel was removed by washing the material in aqueous HCl. By replacing NiCl2 ⋅ 6H2O with anhydrous NiCl2, we obtained a hybrid material of vanadium carbide‐derived carbon and a vanadium carbide core. Material characterization revealed a needle‐like morphology of the rhombohedral V2O3 along with two carbon species with a different degree of graphitic ordering. We varied the NiCl2 ⋅ 6H2O‐to‐VC ratio, and the optimized material yielded a capacity of 110 mAh ⋅ g−1 at 2.5 A ⋅ g−1 which increased to 225 mAh ⋅ g−1 at 0.1 A ⋅ g−1 after 500 cycles in the potential range of 0.01‐3.00 V vs. Li/Li+. This enhanced performance is in stark contrast to the loss of lithium uptake capacity when using commercially available V2O3 mixed with carbon black, where 93 % of the initial capacity was lost after 50 cycles.
A Bayesian network meta‐analysis of the efficacy of targeted therapies and chemotherapy for treatment of triple‐negative breast cancer
Authors: Chen Huihui , Lu Wei , Zhang Yixin , Zhu Xuan , Zhou Jiaojiao , Chen Yiding 
Published: December 2018

AbstractTriple‐negative breast cancer (TNBC) is a heterogeneous disease with poorer prognosis than other subtypes, yet effective therapies are still not available. We aimed to compare the efficacy of various targeted therapies with chemotherapy (CT) in TNBC patients using a network meta‐analysis. A systematic literature search was performed in PubMed, EMBASE, and the Cochrane Library. A total of 27 randomized controlled trials (RCTs), involving 6924 TNBC patients, were included. Olaparib significantly improved PFS (0.43, 0.29‐0.64) and ORR (2.57, 1.31‐5.09) in comparison with CT. As for bevacizumab + CT, it showed a significant improvement of PFS (0.66, 0.55‐0.80) and ORR (2.15, 1.16‐4.05) compared with CT + placebo. It was also superior to CT alone in PFS (0.48, 0.35‐0.65) and pCR (1.30, 1.13‐1.49 for breast and axillary nodes and 1.26, 1.11‐1.44 for breast). Other targeted agents like iniparib, sorafenib, cetuximab, and ipatasertib combined with CT showed significant superiority in PFS compared with CT alone, and the HRs were 0.75 (0.62‐0.90), 0.44 (0.21‐0.91), 0.67 (0.47‐0.96), and 0.44 (0.24‐0.81), respectively, while some other agents such as sunitinib and cetuximab had the lowest SUCRA in OS, PFS, or ORR without any benefits. In conclusion, our results indicated that the addition of bevacizumab to CT was beneficial for TNBC patients, and olaparib had a great effect in PFS and ORR, especially for those with BRCA mutations. When combined with CT, targeted agents including iniparib, sorafenib, cetuximab, and ipatasertib may have better efficacies for treating TNBC.
N‐Doped Defective Graphene from Biomass as Catalyst for CO2 Hydrogenation to Methane
Authors: Jurca Bogdan , Bucur Cristina , Primo Ana , Concepción Patricia , Parvulescu Vasile I. , García Hermenegildo 
Published: December 2018

AbstractN‐doped, defective graphene obtained by pyrolysis of chitosan at 900 °C under Ar exhibits catalytic activity for the Sabatier hydrogenation of CO2 to CH4 at temperatures about 500 °C with estimated turnover frequencies and activation energy values of 73.17 s−1 and 24.3 kcal×mol−1, respectively. It has been found that this enhanced catalytic activity compared to other related doped defective graphenes derives from the presence of pyridinic N atoms that adsorbs CO2 forming carbamate‐type adsorbates.
Equilibrium and Dynamic Absorption of Electrolyte Species in Cation/Anion Exchange Membranes of Vanadium Redox Flow Batteries
Authors: Nguyen Tam D. , Whitehead Adam , Wai Nyunt , Ong Samuel Jun Hoong , Scherer Günther G. , Xu Zhichuan J. 
Published: December 2018

AbstractVanadium redox flow batteries (VRFBs) rely on ion exchange membranes (IEMs) to separate the positive and negative compartments while maintaining electrical neutrality of the cell, by allowing the transport of ionic charge carriers. Cation exchange membranes (CEMs) and anion exchange membranes (AEMs), the two principal types of IEM, have both been employed in VRFBs. The performance of these IEMs can be influenced by the absorption of species from the electrolyte. In this study, a typical commercial CEM (Nafion 117) and AEM (FAP 450), were examined with respect to vanadium uptake, after exposure to electrolyte at different states of charge. The two types of membrane were found to behave very differently, with the AEM showing very high selectivity for VV, which resulted in a significant increase in area‐specific resistivity. In contrast, the CEM absorbed VII more strongly than vanadium in other oxidation states. These findings are essential for the development of an effective membrane for VRFB applications.
Anaerobic digestion of chicken manure: Influence of trace element supplementation
Authors: Molaey Rahim , Bayrakdar Alper , Sürmeli Recep Önder , Çalli Bariş 
Published: December 2018

AbstractIn this study, anaerobic digestion of nitrogen‐rich chicken (egg‐laying hen) manure at different trace element (TE) mix doses and different total ammonia nitrogen (TAN) concentrations was investigated in batch digestion experiments. With respect to nonsupplemented TE sets, addition of TE mixture containing 1 mg/L Ni, 1 mg/L Co, 0.2 mg/L Mo, 0.2 mg/L Se, 0.2 mg/L W, and 5 mg/L Fe at TAN concentrations of 3000 mg/L and 4000 mg/L, cumulative CH4 production and CH4 production rate improved by 7–8% and 5–6%, respectively. The results revealed that at a very high TAN concentration of 6000 mg/L, the effect of TE addition was significantly high and the cumulative CH4 production and production rate were increased by 20 and 39.5%, respectively. Therefore, it is concluded that at elevated TAN concentrations the CH4 production that was stimulated by TE supplementation was presumably occurred through syntrophic acetate oxidation.