bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASSESSMENT OF A NOVEL DYNAMIC HIGH-STRENGTH SUTURE TAPE IN DISTAL TRICEPS TENDON REPAIR: A BIOMECHANICAL COMPARATIVE STUDY
Authors: Zderic I. , Kraus M. , Axente B. , Dhillon M. , Puls L. , Gueorguiev B. , Richards G. , Pape H. C. , Pastor T. , Pastor T. 
Published: November 2024

IntroductionDistal triceps tendon rupture is related to high complication rates with up to 25% failures. Elbow stiffness is another severe complication, as the traditional approach considers prolonged immobilization to ensure tendon healing. Recently a dynamic high-strength suture tape was designed, implementing a silicone-infused core for braid shortening and preventing repair elongation during mobilization, thus maintaining constant tissue approximation. The aim of this study was to biomechanically compare the novel dynamic tape versus a conventional high-strength suture tape in a human cadaveric distal triceps tendon rupture repair model.MethodSixteen paired arms from eight donors were used. Distal triceps tendon rupture tenotomies and repairs were performed via the crossed transosseous locking Krackow stitch technique for anatomic footprint repair using either conventional suture tape (ST) or novel dynamic tape (DT). A postoperative protocol mimicking intense early rehabilitation was simulated, by a 9-day, 300-cycle daily mobilization under 120N pulling force followed by a final destructive test.ResultSignificant differences were identified between the groups regarding the temporal progression of the displacement in the distal, intermediate, and proximal tendon aspects, p<0.001. DT demonstrated significantly less displacement compared to ST (4.6±1.2mm versus 7.8±2.1mm) and higher load to failure (637±113N versus 341±230N), p≤0.037. DT retracted 0.95±1.95mm after each 24-hour rest period and withstood the whole cyclic loading sequence without failure. In contrast, ST failed early in three specimens.ConclusionFrom a biomechanical perspective, DT revealed lower tendon displacement and greater resistance in load to failure over ST during simulated daily mobilization, suggesting its potential for earlier elbow mobilization and prevention of postoperative elbow stiffness.
BIOMECHANICAL EVALUATION OF DOUBLE-STRANDED KNOT CONFIGURATIONS IN HIGH-STRENGTH SUTURES AND TAPES: HOW MANY KNOTS ARE NECESSARY TO ACHIEVE KNOT SECURITY?
Authors: Dhillon M. , Pastor T. , Zderic I. , Pastor T. , Gueorguiev B. 
Published: November 2024

IntroductionRecently, a new dynamic high-strength round suture dynacord (DC) was introduced featuring a salt-infused silicone core attracting water in a fluid environment to preserve tissue approximation which is also available in tape form (DT). Study aims: (1) assess the influence of securing knot number on knot security of two double-stranded knot configurations (Cow-hitch and Nice-knot) tied with either dynamic (DC and DT) or conventional round sutures fiberwire (FW) and conventional suture tapes (ST), (2) compare the ultimate force and knot slippage of (a) Cow-hitch and Nice-knot and (b) DC and DT versus FW and FT at their minimal number of needed securing knots.MethodSeven specimens of each FW, ST, DC and DT were considered for tying with Cow-hitch or Nice-knots. The base of these Cow-hitch and Nice-knots were secured with surgeons’ knots using 1-3 alternating throws. Tensile tests were conducted under physiologic conditions to evaluate knot slippage, ultimate force at rupture, and minimum number of knots ensuring 100% knot securityResult100% knot security for both Cow-hitch and Nice-knots was achieved with 2 securing knots for DC, DT, ST, and with 3 securing knots for FW. With these minimum number of securing knots ultimate force was significantly higher for Nice-knots versus Cow-hitch in DT (p=0.001) and slippage was significantly higher in Cow-hitch versus Nice-knot tied with DC (p=0.019).ConclusionThe minimum number of securing knots required to achieve 100% knot security was 2 for DC, DT and ST both with Cow-hitch and Nice-knots. In contrast, 3 securing knots were needed in FW. With these minimum number of securing knots Nice-knots were associated with higher ultimate forces in DT and lower slippage in DC versus Cow-hitch knots. Furthermore, the novel self-tightening suture material (DT and DC) does not reduce slippage, which is unavoidable in all used sutures.
USE OF BIOABSORBABLE NANOTECHNOLOGY IN ACHILLES TENDON RUPTURES
Authors: Savaş S. , Konya M. , Yılmaz B. K. , Kağa S. , Kağa E. , Demirel H. H. 
Published: November 2024

IntroductionThe Achilles tendon is the thickest and strongest tendon in the human body. Even though the tendon is so strong, it is one of the most frequently injured tendons. Treatment of patients after rupture is planned conservatively and surgically. Conservative treatment is generally applied to elderly patients with sedentary lives. If the treatment is surgical, it can be planned as open surgery or percutaneous surgery. In our study with rabbits, we wrapped a membrane made of plga (polylactic-co-glycolic acid) nanotubes impregnated with type 1 collagen around the tendon in rabbits that underwent open Achilles tendon repair surgery. After surgery, biomechanical and histological tests were performed on the tendons.MethodIn the study consisting of 24 rabbits, 2 groups were created by random distribution. In the study group, after the Achilles tendon rupture was created, a type 1 collagen-impregnated plga-based membrane was placed around the tendon after the repair of 1 modified Kesslerr suture. In the control group, after the Achilles tendon rupture was created, 1 modified Kessler suture and Tendon repair was performed with the application of 3 primary sutures. At the end of the 6th week of the study, the rabbits in 2 groups were randomly distributed and histological examination was performed. Additionally, biomechanical testing was performed. Bonar and Movın scoring were used in histological examinations.ResultAs a result of biomechanical tests, it was seen that the resistance of the tendon against rupture was higher in the study group than in the control group. In addition, it was observed that the tendon rupture time was longer in the study group than in the control group. Histological examinations gave supportive results from biomechanical tests.ConclusionWe think that the use of collagen-impregnated plga-based nanotubes in the surgical treatment of Achilles tendon ruptures has a positive healing effect. Although we think that the return to normal life after surgery may be faster, we believe that more clinical studies are needed.
Exploring ADHD understanding and stigma: Insights from an online survey in Lebanon
Authors: Younes Samar , Hajj Aline , Sacre Hala , Mourad Nisreen , Akel Marwan , Haddad Chadia , Sakr Fouad , Zeenny Rony M. , Salameh Pascale 
Published: November 2024

Background
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder. Public knowledge of ADHD plays a crucial role in shaping attitudes, reducing stigma, and fostering a supportive environment for individuals with this disease. This study aimed to assess the level of knowledge and stigma of the general Lebanese population regarding ADHD and identify potential factors associated with these variables.

Methods
An online cross-sectional study was conducted between July and August 2023 among adults from all Lebanese regions. The questionnaire was self-administered, available in Arabic and English, and included a sociodemographic section and the validated tools Knowledge of Attention Deficit Disorders Scale (KADDS) and the ADHD Stigma Questionnaire (ASQ).

Results
A total of 647 participants were included. Most participants (n = 483 (74.7%)) lacked prior experience with individuals who have ADHD, and only 12.8% reported having good information about the condition. The participants had a mean knowledge score of 20.49 ±3.23 and a mean ADHD stigma score of 75.71 ±20.58. A significantly higher knowledge score was associated with a university level of education (B = 0.14, p < 0.001), older age (B = 0.14, p = 0.001), using the internet (B = 0.13, p = 0.001) and lecture (B = 0.09, p = 0.015) as a source of ADHD information, having a high monthly income (B = 0.13, p = 0.001), being female (B = 0.08, p = 0.030) and having a health coverage (B = 0.08, p = 0.025). Conversely, a lower knowledge was significantly associated with obtaining ADHD information from television (B = -0.13, p = 0.001) and family (B = -0.08, p = 0.043). A significantly lower score was associated with ever being diagnosed with ADHD (B = -0.18, p < 0.001), having an intermediate monthly income (B = -0.10, p = 0.005), and consuming alcohol (B = -0.11, p = 0.004), while a higher score was significantly associated with a higher KADDS total score (B = 0.12, p = 0.002) and being employed (B = 0.07, p = 0.044).

Conclusion
The present study addressed a gap in the existing literature by examining ADHD knowledge and stigma in the Lebanese population. Surprisingly, a positive correlation between higher ADHD knowledge and increased stigma challenges common assumptions, suggesting a complex relationship between knowledge, misconceptions, and societal attitudes. The findings emphasize the need for targeted education and advocacy to improve knowledge and alleviate misconceptions and stigma within the general population.
Rehabilitation and violence-related traumatic brain injury: A scoping review
Authors: Omar Samira , Estrella Maria Jennifer , Ahmad Muzna , Colantonio Angela , Babineau Jessica , Chan Vincy 
Published: November 2024

Objectives
There is a dearth of reviews exploring rehabilitation for violence-related traumatic brain injury (TBI) despite its increasing rates and distinct risk factors and outcomes. The aim of this scoping review is to determine the extent to which rehabilitation is available to and accessed by people who sustain TBI from interpersonal violence.

Method
Electronic databases (i.e., MEDLINE, Cochrane CENTRAL Register of Clinical Trials, CINAHL, APA PsycINFO, Criminal Justice Abstracts, Applied Social Sciences Index and Abstracts, and Proquest Nursing and Allied Health) and grey literature (i.e., relevant organizations’ websites) were systematically searched for peer-reviewed articles and reports that met eligibility criteria. To be included, articles had to report primary findings on rehabilitation interventions that included individuals who sustained a TBI through interpersonal violence. Articles based on the military population were excluded. Data were synthesized through a descriptive numerical summary and qualitative content analysis.

Results
Fifty-two primary research articles and five grey literature reports were included. Most (77.2%) of these articles described rehabilitation interventions that addressed TBI sequalae without consideration for violence as a mechanism of injury, beyond reporting sample characteristics. Only thirteen articles (22.4%) considered violence-related TBI by investigating the rehabilitation profile (13.8%) or designing programs specifically for survivors of violence-related TBI (8.6%). There was limited attention to social determinants of health across all studies.

Conclusion
This is the first scoping review to our knowledge that explored the extent and nature of rehabilitation among persons who experience TBI through violence in civilian populations. Priorities for education, research, and practice are identified.
Efficacy of platelet-rich plasma in the treatment of erectile dysfunction: A meta-analysis of controlled and single-arm trials
Authors: Du Shaokang , Sun Shiwei , Guo Fuyu , Liu Hongyao 
Published: November 2024

Background
Erectile dysfunction (ED) is a prevalent condition in urology, and studies on the effectiveness of platelet-rich plasma (PRP) for this condition have been conducted; however, the evidence remains inconclusive. This meta-analysis aimed to evaluate the effectiveness of PRP in treating ED.

Methods
On May 17, 2024, a literature search was performed and evaluated using the Cochrane method. The primary outcome measured was the International Index of Erectile Function (IIEF) score, while the secondary outcomes included Minimal Clinically Important Difference (MCID) and peak systolic velocity (PSV).

Results
A total of 12 controlled trials involving 991 patients and 11 single-arm trials with 377 patients were analyzed. The findings revealed that compared to the control group, the PRP group demonstrated better outcomes in terms of the IIEF score and MCID (SMD = 0.59 (95% CI: [0.34, 0.84]; RR = 1.94 (95% CI: [1.33, 2.83]), In the single-arm trials, a significant improvement in IIEF scores was observed following PRP treatment (SMD = -0.99 95% CI: [-1.53, 0.46]).

Conclusion
PRP appears effective in treating erectile dysfunction, but further high-quality, large-sample trials with longer follow-up are needed to fully understand its effects.
Associations between urinary phytoestrogen mixed metabolites and osteoarthritis risk
Authors: Huang Dichao , Wang Hua , Wang Shuguang , Yu Tianming , Zhou Long 
Published: November 2024

Background
This study aims to explore the relationship between urinary phytoestrogen mixed metabolites and the risk of osteoarthritis (OA).

Methods
Using data from the National Health and Nutrition Examination Survey (NHANES), a Weighted Quantile Sum (WQS) regression analysis was conducted to determine the dominant metabolites. Additionally, a Bayesian kernel machine regression (BKMR) model was utilized to explore the combined effects of phytoestrogen mixed metabolites on OA.

Results
Compared to the lowest quartile group, the highest quartile group of Enterodiol showed a 46% increased risk of OA (OR = 1.46, 95% CI: 1.09–1.96), while the highest quartile group of Enterlactone showed a 30% decreased risk of OA (OR = 0.70, 95% CI: 0.52–0.96). The WQS regression model analysis revealed a positive relationship between urinary phytoestrogen mixed metabolites and OA risk, with Enterodiol found to have the highest weight in this association. The BKMR model indicated that the association between urinary phytoestrogens and OA increased with concentration but did not reach statistical significance. The univariate exposure-response function demonstrated a positive association between Enterodiol and OA.

Conclusions
There is a positive relationship between urinary phytoestrogen mixed metabolites and OA, with Enterodiol being an important factor influencing OA risk.
Safety and Effectiveness of Glucagon-like Peptide-1 Receptor Agonists in Inflammatory Bowel Disease
Authors: Anderson Scott R. , Ayoub Malek , Coats Sarah , McHenry Scott , Tan Tingyi , Deepak Parakkal 
Published: November 2024

INTRODUCTION:
The safety and effectiveness of glucagon-like peptide receptor agonists (GLP1-RA) in patients with inflammatory bowel disease (IBD) are poorly understood.

METHODS:
Patients with IBD treated with GLP1-RA were retrospectively identified for outcomes of adverse events, weight change, and clinical, endoscopic, and biomarker response.

RESULTS:
Among a total of 120 patients with IBD, gastrointestinal side effects being the most common (11.5%). Semaglutide showed the most significant weight reduction. C-reactive protein levels decreased after one year (P = 0.005). No differences were observed in IBD-related hospitalizations or endoscopic scores.

DISCUSSION:
GLP1-RA therapy appears safe and effective, with an associated C-reactive protein reduction, in patients with IBD.
Tradition of Crisis: Kabbalistic Transmission in Early Modern Kraków
Authors: Kelman Avraham Oriah 
Published: November 2024

Abstract
Despite the importance the kabbalistic tradition ascribes to oral transmission, many early modern kabbalists complained about a lack of access to personal tutoring and described a crisis of kabbalistic transmission. This article explores the concept of »transmission crisis« in the writings of the Ashkenazi scholar Moshe Isserles (Kraków, d. 1572), contextualizing it in a broader sixteenth-century Jewish discourse. Isserles believed that the full, esoteric meaning of kabbalah is inaccessible to us, devoid as we are of oral tradition. He insisted, however, on interpreting kabbalah on an exoteric level, without the pretense of an ultimate mystical understanding. This gave rise to Isserles’ »hermeneutics of immanence«, in which kabbalistic depictions of the divine are translated into the mundane realm. Isserles represents a model of a sixteenth-century Ashkenazi scholar, striving to make sense of the Sephardic kabbalistic tradition, which newly arrived in Poland and filled the study halls with admiration and bewilderment.
Praying with Moses Cordovero: Adopting and Adapting Spanish Kabbalah in Italy and East-Central Europe
Authors: Matanky Eugene D. 
Published: November 2024

Abstract
This article explores Moses Cordovero’s (1522–1570) commentary on the Rosh Hashanah liturgy and its reception among Italian and East-Central European Jews, highlighting its intersections with broader issues in early modern Jewish history, such as manuscript and print cultures, individual mobility, and the dissemination of knowledge. Through an in-depth analysis of three documents—an annotated printed Mahzor and two manuscripts written in Ashkenazi script—the article demonstrates how individuals enhanced and adapted Cordovero’s kabbalistic intentions for their own liturgical practices. The study traces the journey of Cordovero’s commentary from manuscript to print and back into manuscript, emphasizing the personal stories and material transformations that made this text a practical tool for prayer. Ultimately, the article provides insights into the dynamic interplay between Cordoverean kabbalah and local liturgical rites, illustrating how early modern Jews actively engaged with and reshaped their devotional texts.
Translating, Editing and Printing
Tikkunim
in Old Yiddish
Authors: Baumgarten Jean 
Published: November 2024

Abstract
The Old Yiddish literature printed in the seventeenth and eighteenth century abounds with references to kabbalah. This study focuses on the monolingual and, for the vast majority, bi- or trilingual (Aramaic, Hebrew, Yiddish) collections of Tikkunim connected to kabbalistic prayers and rituals. These collections contain fragments from the Bible, midrashim, Sefer ha-Zohar, Lurianic customs, and collections of mystical stories. The article provides a typology of Yiddish chapbooks of prayers for the less educated readers, centering on Tikkunei ha-Mo’adim by Aryeh ben Yehuda Seligman of Binswangen. In considering the question of the authorship and readership of this chapbook, the article presents several prayers and excerpts from kabbalistic texts adapted into Yiddish.
Controllability and diffeomorphism groups on manifolds with boundary
Authors: Grong Erlend , Schmeding Alexander 
Published: November 2024

Abstract
In this article we consider diffeomorphism groups of manifolds with smooth boundary. We show that the diffeomorphism groups of the manifold and its boundary fit into a short exact sequence which admits local sections. In other words, they form an infinite-dimensional fibre bundle. Manifolds with boundary are of interest in numerical analysis and with a view towards applications in machine learning we establish controllability results for families of vector fields. This generalises older results due to Agrachev and Caponigro in the boundary-less case. Our results show in particular that the diffeomorphism group of a manifold with smooth boundary is generated by the image of the exponential map.
The multiplicative Lie algebra on general linear groups
Authors: Kumar Akshay , Kushwaha Seema , Upadhyay Sumit Kumar 
Published: November 2024

Abstract
The main aim of this paper is to study an obvious linear representation of a multiplicative Lie algebra. Also, we find some criteria to determine all possible multiplicative Lie algebra structures on a general linear group and we show that the general linear group on a finite field is a Lie simple group.
Determination of lower order perturbations of a polyharmonic operator in two dimensions
Authors: Bansal Rajat , Krishnan Venkateswaran P. , Pattar Rahul Raju 
Published: November 2024

Abstract
We study an inverse boundary value problem for a polyharmonic operator
in two dimensions. We show that the Cauchy data uniquely determine all the anisotropic perturbations of orders at most

m
-
1

{m-1}

and several perturbations of orders m to

2
⁢
m

-
2

{2m-2}

under some restriction. The uniqueness proof relies on the

∂
¯

{\bar{\partial}}

-techniques and the method of stationary phase.
Thermal-hydraulic and safety analysis of alternative ceramic fuels in next generation of VVER-1000 reactor
Authors: Rahimi Ahmad , Kheradmand Saadi Mohsen , Heidari Ebrahim , Abbasi Kavoos 
Published: November 2024

Abstract
The main aim of this study is the thermohydraulic and safety analysis of alternative UN and UC ceramic fuels in the next generation of VVER-1000/V446 reactor core. One of the advantages of these alternative fuels is their higher thermal conductivity and density relative to the UO2 conventional fuels. Thermohydraulic analysis has been performed under full power conditions. Also, the safety evaluation of alternative ceramic fuels has been researched by the Rod Ejection Accident (REA) scenario. RELAP5 Mod3.2 code is used for thermo-hydraulic analysis in both steady state and transient state in VVER-1000/V446 reactor. In addition, calculations of the fuel center temperature in mean and hot channels for steady state, the temperature of the hottest rod in the fuel assembly, the radial distribution of fuel temperature for both channels, and the maximum clad temperature during the reactivity injection have been performed. The results showed that in the steady state with full power, the fuel centreline temperature in UO2 is about twice the corresponding values for UN and UC alternative fuels which is very attractive from a safety point of view. In general, due to the large difference between the hot spot point and the melting point in alternative fuels, the thermal power and safety factors can be significantly increased in the next generation of VVER-1000/V446 reactors.
Analyse der Einkommens- und Beschäftigungswirkungen einer Einführung des CDU-Konzepts der „Aktiv-Rente“
Authors: Brüll Eduard , Pfeiffer Friedhelm , Ziebarth Nicolas 
Published: November 2024

Zusammenfassung
Im September 2023 stellte die CDU das Konzept der „Aktiv-Rente“ vor. Die Idee dahinter ist, den Arbeitsverdienst von Rentnerinnen und Rentnern, die neben dem Bezug einer gesetzlichen Rente eine bezahlte Beschäftigung aufnehmen, bis zu 2.000 Euro pro Monat steuerfrei zu stellen. Diese Steuerbefreiung soll unter anderem die Arbeitsanreize verbessern sowie dem Fachkräftemangel entgegenwirken. Eduard Brüll, Friedhelm Pfeiffer und Nicolas R. Ziebarth quantifizieren die möglichen Auswirkungen der Aktivrente auf die Beschäftigung von Rentnerinnen und Rentnern sowie auf die Nettoeinkommen der beschäftigten Ruheständler im Alter von 63 bis 73 Jahren auf der Basis von Stichproben des Sozio-oekonomischen Panels (SOEP) von 2019. Weil die verfügbaren Einkommen durch eine Aktivrente im Mittel um 5,5 Prozent stiegen, würden nach ihrer Analyse 5.000 bis 15.000 Ruheständler zusätzlich arbeiten. Mithin könne eine Aktivrente selbst unter optimistischen Annahmen dem Fachkräftemangel aus gesamtwirtschaftlicher Sicht wohl nur in begrenztem Umfang entgegenwirken. Außerdem gebe es mögliche unerwünschte Nebenwirkungen.