bluuebunny/crossref_metadata_2025_split huggingface dataset:
HEMODYNAMIC AND BIOELECTRICAL PROPERTIES OF THE BRAIN IN YOUNGER ADULTS WITH NONSTABLE BLOOD PRESSURE
Authors: Efremushkin G. G. , Filippova T. V. , Kharlova A. G. , Dekhar V. V. 
Published: August 2018

Aim.To study macro- and microhemodynamics and bioelectrical properties of the brain in younger adults with nonstable blood pressure (BP).Material and methods.A population of 79 adults at the age of 19–24 (average 19,9±0,9 years) was examined. According to the BP level they were divided into two groups: 1–46 (58,5%) with stable normal BP (SNBP), and 2–33 (41,5%) with high normal BP inside the range for 1stlevel arterial hypertension, whose BP was not stable (UsBP), but changing from normal values to 1st level hypertension. All patients undergone investigation of brachiocephal and intracerebral vessels with blood flow velocity measurement along the vessel direction, the blood sectional volumetric flow and specific kinetic energy. Microcirculation in the brain was measured by rheoencephalography including parameters of the velocity, time and volumetric parameters. Bioelectricity studied by electroencephalography.Results.In patients with UsBP we found the increase of blood flow velocity, blood volume and specific kinetic flow energy in vertebral and general carotid arteries as in basilar and middle cerebral arteries to. In the area of microcirculation in patients with UsBP the blood filling of frontal lobes was decreased comparing to SNBP patients in whom blood filling showed “mosaic” pattern. In UsBP patients we found changes of bioelectrical activity which are related to the functioning of cortical and subcortical portions of the brain.Conclusion.In younger patients with UsBP there is developed discirculatory encephalopathy with damage of cortex and subcortical portions of the brain due to impaired hemodynamic and microcirculation.
SEVERAL ASPECTS OF DILTIAZEM AND ORGANIC NITRATES USAGE IN VARIOUS SEVERITY STABLE ANGINA PATIENTS
Authors: Butina E. K. , Bochkareva E. V. , Pozdnyakova N. A. 
Published: August 2018

Aim. To estimate the effectiveness of Diltiazem (Dlt) and its combination with nitrates in patients with ischemic heart disease (CHD) and arterial hypertension (AH) according to exercise tolerance by functional class (FC) of stable angina (StA).Material and methods. 30 CHD male patients at the age of 58,8±7,5 with StA II FC (n=11), III FC (n=19) and 1–2 stage AH were included into open randomized placebo-controlled study. Drug therapy: Dlt 90–180 mg bid, isosorbide 5-mononitrate 50 mg qd, trinitrolong 2 mg bid or tid. Effectiveness of the regular drug intake was controlled by repeated exercise tolerance tests (ETT) by treadmill with the value of threshold effort time (ThT). Total duration of treatment was 4 weeks.Results. At the beginning the ThT was 249,8±23,4 s for III FC and 368,6±14,4 s for II FC patients (p=0,0001). One dose of Dlt increased ThT in 5 hours to 387,3±37,5 s and 533,7±20,3 s in both groups, respectively (p=0,001), with the difference between groups being held. During regular Dlt intake the ThT in III FC angina patients reached 441,1±26,8 s, but in II FC patients in has not changed: 526,1±22,0 s. Additional nitrate intake to III FC group led to even more increase of ThT; in II FC patients there was no improvement. Combination therapy by Dlt and nitrates has not led to differences between III and II FC groups by achieved exercise tolerance. Hemodynamic parameters in both groups has not differ.Conclusion. For patients with III FC stable angina it is recommended to prescribe Dlt with nitrates because of additional effectiveness of combination that might be linked to the influence on cardiac hemodynamics and to improvement of myocardium metabolism. In II FC stable angina Dlt alone reaches its maximum antiischemic effect so the addition of nitrates is not helpful.
STUDYING ATRIAL FIBRILLATION ON THE BASIS OF THE “PROFILE” REGISTRY
Authors: Martsevich S. Yu. , Navasardian A. R. , Kutishenko N. P. , Drozdova L. Yu. , Zakharova A. V. , Kiseleva N. V. 
Published: August 2018

Aim.To research the prevalence of atrial fibrillation (AF) and to compare the clinical characteristics of the patients to those without AF.Material and methods.At the moment of cross-section the Profile Study included 671 patients with various cardiovascular diseases, those who consulted at the Preventive pharmacotherapy department of the Centre.Results.AF was diagnosed in 99 patients (14,7%). There was no difference by gender with those without AF, but they were significantly older. There was no difference in prevalence of the common risk factors, ischemic heart disease and peripheral atherosclerotic disease. Anamnesis of cerebral stroke was more common for the AF group: 9,1% vs 2,8%. Anamnesis of stomach ulcer disease was also more prevalent in AF group: 9,1% vs 4,4%.Conclusion.The section-study of patients included into Profile Registry showed typical clinical properties for AF and made it to compare with those found in other registries.
KIDNEY DYSFUNCTION EVALUATION IN CHRONIC HEART FAILURE PATIENTS
Authors: Kamilova U. K. , Alikulov I. T. 
Published: August 2018

Aim. To study the signs of kidney dysfunction in chronic heart failure (CHF).Material and methods. We included 96 patients with postinfarction cardiosclerosis and CHF with the age of 40–60 years. Patients were divided into two groups by functional class (FC) of CHF according to NYHA. In all patients the levels of serum creatinine and MDRD glomerular filtration rate (GFR), urine alanine transferase, aspartat transferase, alkaline phosphatase and cholinaestherase by spectrophotometric method were measured.Results. In 33,3% of patients with II FC NYHA and in 66,67% with III FC NYHA we found GFR less than 60 ml/min/1,73 sq.m. Investigation of fermenturia levels in those according to renal functioning showed more prevalent increase of urine enzymes in lower GFR, in whom the patients with III FC NYHA consisted 66,67%. The level of ALT was 39% (p<0,01) higher and AP 35% (p<0,001) higher comparing to subjects without renal dysfunction.Conclusion. In patients with chronic heart failure as the diseases progresses there is kidney dysfunction developing with the decrease of GFR, increase of resdual nitrogen and enzimes in urine. Enzyme levels testing in urine of CHF patients can be a part of diagnostic approach to kidney dysfunction diagnostic at earlier stages.
Influência das variáveis antropométricas sobre a força muscular do assoalho pélvico na Incontinência Urinária
Authors: Mansour Kamila Mohammad Kamal , Goulart Cássia da Luz , Dos Santos Lucas Sidnei , Carvalho Luana , Schuh Claudia Maria , Sudbrack Ana Cristina 
Published: August 2018

INTRODUÇÃO: A Incontinência Urinária (IU) é definida como qualquer perda involuntária de urina. O aumento do peso e as medidas de circunferências elevadas são fatores de risco para o desenvolvimento destes sintomas. OBJETIVO: Avaliar a influência das variáveis antropométricas (VAs) na força muscular do assoalho pélvico de mulheres com IU. MATERIAIS E MÉTODOS: Estudo transversal com amostragem de conveniência. Iniciada a avaliação com a anamnese, após aferição das VAs seguiu-se para avaliação funcional do assoalho pélvico (AFA). Aplicada correlação de Spearman, e para avaliar a influência das VAs na AFA realizou-se regressão linear múltipla. RESULTADOS: Avaliadas 12 voluntárias com IU, média de idade 56,9±13,2 anos e maior frequência 10 (83,3%) de incontinência urinária de esforço. Encontradas correlações moderadas e negativas entre VAs e a AFA [Índice de massa corporal (IMC) vs AFA (r= -0,582 p=0,020); Circunferência da Cintura (CC) vs AFA (r= -0,567 p=0,033); Circunferência do Quadril (CQ) vs AFA (r= -0,593 p=0,050); Circunferência Abdominal (CA) vs AFA (r= -0,657 p=0.001)]. Estes achados foram ratificados através da análise de regressão linear múltipla, onde há influência direta de 37% do IMC e CA na AFA das voluntárias com IU. CONCLUSÃO: Valores elevados das VAs estão relacionadas diretamente com um pior desempenho na AFA, em mulheres com incontinência urinária.
Défis et évolution de l'accompagnement offert aux professeurs de langue par le Régime d'immersion en français (RIF) de l'Université d'Ottawa
Authors: Thibault Laurence Valérie , Gobeil Marc 
Published: August 2018

Depuis 2006, le RIF offre des cours d’encadrement linguistique (CEL) associés à des cours de discipline enseignés dans cinq facultés de l’université (soit 86 programmes en 2016-2017). Cependant, les professeurs de FLS sont très rarement formés à l’enseignement propre à ce type de cours qui sont développés sur mesure en lien avec chaque cours de discipline. Pour répondre à ce défi, le RIF offre, par l’entremise des responsables pédagogiques, un accompagnement dont la nature et le format ont évolué au fil des ans.D’abord, les professeurs ont reçu une formation initiale (création de ressources, réunions, ateliers, observations de classes suivies de recommandation) (Weinberg, A., et S. Burger, 2006). Puis, les responsables pédagogiques ont créé deux recueils rassemblant des activités conçues par les professeurs désormais expérimentés (Dansereau et Buchanan, 2009, 2011; Dansereau, 2011). Ces recueils sont devenus des incontournables pour les nouvelles recrues et ont contribué au développement d'une communauté de pratique. Aujourd'hui, l'accompagnement se caractérise par des consultations, des rencontres de partage de pratique et la vérification du respect des objectifs pédagogiques dans les plans de cours.Dans quelle mesure l’accompagnement reçu jusqu’à présent répond-il aux besoins des professeurs? Quels sont leurs nouveaux besoins ? Dans quelle direction et sous quelle forme l’accompagnement peut-il évoluer de façon à maximiser et reconnaître les savoir-faire développés par cette communauté de pratique afin qu’elle profite au plus grand nombre? Grâce aux résultats d’un sondage envoyé en janvier 2017 à tous les professeurs ayant enseigné un CEL depuis 2006 nous pouvons identifier les forces et les faiblesses de l’accompagnement déjà offert et envisager la mise en place de nouvelles stratégies d’accompagnement.
Student Motivation, Identity and Investment Construction in French Immersion Studies at the University of Ottawa
Authors: Flynn Peggy 
Published: August 2018

AbstractThis article focusses on the motivating factors behind the decision of first-year students in the French Immersion Studies (FIS) program at the University of Ottawa to continue their immersion studies at a university level, how they experience their studies within this program, and how this experience impacts their identity and investment in French language and culture. The findings presented are part of a study that demonstrates the positive influence that parents, teachers and relevant extracurricular experiences have on students’ decision to continue their immersion studies as well as the transformations of the students’ identity construction and investment which are enhanced through the FIS program, the bilingual environment which surrounds it, and students` activities.Keywords: motivation, identity, investment, French Immersion Studies RésuméCet article porte sur les facteurs qui ont motivé des étudiants en première année d’études à s’inscrire au programme du Régime d’Immersion Française (RIF) de l’Université d’Ottawa afin de poursuivre leurs études en immersion au niveau universitaire, leurs expériences dans ce programme ainsi que l’impact que ce programme a sur leur identité et investissement dans la langue et la culture françaises. Les résultats présentés font partie d’une étude qui montre l’influence positive des parents, enseignants, et expériences pertinentes hors programme sur la décision des étudiants de continuer leurs études en immersion ainsi que la transformation associée à leur construction identitaire à l’augmentation de leur investissement à la suite de participation dans le programme RIF, l’environnement bilingue qui l’environne et les activités des étudiants. Mots -clés : motivation, identité, investissement, Régime d’Immersion Française
Lessons learned from immersion in western Canada’s multilingual and multicultural post-secondary context across the disciplines
Authors: Spiliotopoulos Valia 
Published: August 2018

The current educational context in post-secondary institutions world-wide is characterized by a widening participation agenda, and is greatly impacted by trends in globalization and internationalization (Burbules & Torres, 2000, Ilieva, Beck, & Waterstone, 2014). This multilingual and multicultural educational context brings about many opportunities and challenges for students, faculty, and other internal and external stakeholders (Arkoudis et al, 2012; Hafernick & Wiant, 2012; Murray, 2016). Given Canada’s increasing involvement in offering programs predominantly in English to international, transnational, and bi/plurlilingal domestic students, it is important to examine the lessons learned from Canada’s history with immersion (Cummins, 1998). and consider the implications for the post-secondary context (Knoerr, et al. 2016). To that end, it is perhaps time to reconsider language education policies, re-examine how language is used as a medium of instruction, redesign curriculum and instruction, as well as understand how students’ bi/plurlingualism can serve as an additional resource for learning across the disciplines (Camarata, 2016; Coste, Moore & Zarate, 2009; Cummins, 2007; Marshall and Moore, 2013).

This article describes the educational development and scholarly activities of a Centre for English Language Learning Teaching, and Research at a comprehensive university in British Columbia, and shares emergent findings of a case study and pilot projects in which faculty in applied linguistics/language education collaborate with faculty across the disciplines to support students’ English language development alongside their disciplinary knowledge and literacy skills at the curricular, instructional, and assessment levels. Key practices and approaches in university French immersion education will be compared and contrasted with Content-based/‘CLIL’ and plurilingual approaches used by language education faculty working alongside disciplinary faculty in order to support students at the curricular core within programs where English is the language of instruction.
Utilization of urine protein/creatinine ratio in pregnancy for diagnosis of preeclampsia
Authors: Bhadarka Nagajan , Poddar Krutika , Joshi Satyam 
Published: August 2018

Background: The aim of the present study was to evaluate the ability of the random urine P/C ratio to predict significant proteinuria, as well as to introduce a diagnostic test for preeclampsia that would avoid the inconvenience and time consumption of 24-hour urine protein collection.Methods: A total of 100 women who were pregnant were included in the study. For urine test, the urine was collected for 24 hours. The women patients provided the mid stream urine sample prior to the collection period. Biuret colorimetric assay was used to determine the total protein in the urine and the creatinine concentration was measured with the help of modified Jaff test.Results: The mean urinary protein excretion in 24 hour urine collection was found to be 2.05±0.74 g/dl and the median serum creatinine concentration was found to be 0.82 mg/dl. The mean p/c ratio was found to be 1.94±0.83. The correlation coefficient for the p/c ratio against the 24 hour urine protein excretion was found to be 0.88.Conclusions: This test can also be used as a reasonable alternative to 24-hour urine protein excretion, especially in emergency situations, and, it could also complement the urinary dipstick test in preeclamptic pregnancy.
Microshear bond strength of conventional and self-adhesive resin cements to feldsphatic ceramic
Authors: Couto Estéfani Maminis Soares , Reis Bruna de Oliveira , Suzuki Thaís Yumi Umeda , Assunção Wirley Gonçalves , Briso André Luiz Fraga , Santos Paulo Henrique dos 
Published: August 2018

Aim: The aim of this study was to verify the microshear bond strength of conventional and self-adhesive resin cements to feldsphatic ceramic. Methods: Twenty discs of Starlight ceramic (Degudent) were made (15mm x 2mm). The bonding procedure was accomplished by insertion of resin cements into tubes of 0.7mm internal diameter in contact with the ceramic. The resin cements used were: RelyX ARC (3M Espe), Panavia F (Kuraray), RelyX Unicem (3M Espe) and seT (SDI). Total of six tubes of each material on each ceramic disc. The specimens were tested for microshear in a universal testing machine, 24hours and 6months after bonding procedure. Values of microshear bonding strength (MPa) were subjected to ANOVA and Fisher PLSD test (p<0.05). Results: For 24hours analysis, RelyX ARC showed the highest microshear bonding strength without statistical difference to RelyX Unicem and seT. Panavia F showed the lowest values of microshear bonding strength in both periods. In the analysis after 6months there was a significant increase in the microshear bonding strength values for all cements compared to 24hours. Only for RelyX ARC, the increase was not statistically significant. Conclusion: In conclusion, the bond strength depends mainly on the type of resin cement used, and the self-adhesive cements behave similarly to conventional resin cement.
Simplified micrometric surface characterization of different implant surfaces available on the Brazilian market
Authors: Carmo Filho Luiz Carlos do , Martins Ana Paula Pinto , Bielemann Amália Machado , Possebon Anna Paula da Rosa , Faot Fernanda 
Published: August 2018

Aim: This study characterized the implant surfaces available on the Brazilian market in terms of topography, chemical composition, and roughness. Methods: The following brands were selected according to their surfaces: Kopp (Ko), Signo Vinces (Sv), Neodent (Ne), Osseotite (Os) NanoTite (Nt), SIN (Si), Titanium Fix (Tf), conventional Straumann (Str), Active SLA (SLA). The morphological analysis and the alloy impurities and implant surface contaminants were analyzed by SEM-EDS. Surface roughness parameters and 3-D reconstructions were obtained by laser microscopy (20x). Two distinct areas were evaluated: i) the cervical portion (no surface treatment), and ii) the middle third (treated surface). Results: The characterization of the implant surfaces by SEM showed morphological differences between the thread geometries and surface morphology at 800x and 2000x magnification. The EDS elemental analysis showed a predominance of titanium (Ti) for all implants. The SLA surface showed only peaks of Ti while other implants brands showed traces of impurities and contaminants including Al, C, PR, F, Mg, Na, Ni, O, P, and SR. The implant surface roughness in the cervical portion did not exceed Ra 0.5–1.0 μm, constituting a minimally rough surface and obtaining acceptable standards for this region. Only Nt, Str, and SLA presented Ra above 2 μm in the middle third area showing a rough surface favorable for osseointegration. Conclusion: This study concluded that there is no established standard for morphology, chemical composition and implant surface roughness that allows a safe comparison between the available dental implant surfaces. National implant brands generally contain more impurities and surface contaminants than their international counterparts and were consequently more sensitive to the surface treatment techniques.
A cidade capitalista e o progresso gentrificador: o processo de remodelação do Anhangabaú (1877-1917)
Authors: Oliveira Rafael Carlos Lima 
Published: August 2018

O artigo visa discutir de que maneira os processos de urbanização em curso na São Paulo da virada do séc. XIX - XX podem ter sido utilizados para engendrar discursos “gentrificadores” sobre regiões centrais específicas da cidade – pobres, encortiçadas, de meretrício e comércio simples. Nessas regiões, que constituíam um campo imobiliário fértil para a expansão e remodelação da cidade, existia uma preocupação moralizante da elite (principalmente no que tange a questão do meretrício) e um projeto de cidade espacialmente incompatível com as camadas baixas. Dentro desse espectro, elege-se como foco o processo de remodelação do Anhangabaú, iniciado com o anúncio do projeto de construção do primeiro Viaduto do Chá (1877) até a finalização das obras do Parque Anhangabaú (1917).
Hormonal, Metabolic and Hemodynamic Adaptations to Glycosuria in Type 2 Diabetes Patients Treated with Sodium-Glucose Co-Transporter Inhibitors
Authors: Cersosimo Eugenio , Miles John M. 
Published: August 2018

Background & Introduction:The advent of the sodium-glucose cotransporter-2 inhibitors [SGLT-2i] provides an additional tool to combat diabetes and complications. The use of SGLT-2i leads to effective and durable glycemic control with important reductions in body weight/fat and blood pressure. These agents may delay beta-cell deterioration and improve tissue insulin sensitivity, which might slow the progression of the disease.Methods & Results:In response to glycosuria, a compensatory rise in endogenous glucose production, sustained by a decrease in plasma insulin with an increase in glucagon has been described. Other possible mediators have been implicated and preliminary findings suggest that a sympathoadrenal discharge and/or rapid elevation in circulating substrates (i.e., fatty acids) or some yet unidentified humoral factors may have a role in a renal-hepatic inter-organ relationship. A possible contribution of enhanced renal gluconeogenesis to glucose entry into the systemic circulation has not yet been ruled out. Additionally, tissue glucose utilization decreases, whereas adipose tissue lipolysis is stimulated and, there is a switch to lipid oxidation with the formation of ketone bodies; the risk for keto-acidosis may limit the use of SGLT-2i. These metabolic adaptations are part of a counter-regulatory response to avoid hypoglycemia and, as a result, limit the SGLT-2i therapeutic efficacy. Recent trials revealed important cardiovascular [CV] beneficial effects of SGLT-2i drugs when used in T2DM patients with CV disease. Although the underlying mechanisms are not fully understood, there appears to be “class effect”. Changes in hemodynamics and electrolyte/body fluid distribution are likely involved, but there is no evidence for anti-atherosclerotic effects.Conclusion:It is anticipated that, by providing durable diabetes control and reducing CV morbidity and mortality, the SGLT-2i class of drugs is destined to become a priority choice in diabetes management.