bluuebunny/crossref_metadata_2025_split huggingface dataset:
AVALIAÇÃO DA VIABILIDADE DE IMPLANTAÇÃO TÉCNICA E ECONÔMICA DE UMA USINA DE RECICLAGEM DE RESÍDUOS SÓLIDOS DA CONSTRUÇÃO CIVIL EM ITAJUBÁ-MG
Authors: Fonseca Thales Daniel dos Santos , Ribeiro Junior Leopoldo Uberto 
Published: June 2018

Os resíduos sólidos da construção civil impactam de forma negativa no meio ambiente pelo grande montante gerado, apesar de sua reciclagem ser possível, por isso este trabalho buscará demonstrar que a implantação de uma usina de reciclagem destes resíduos é viável economicamente. Para demonstrar o interesse econômico positivo gerado foram utilizados os métodos do payback, do valor presente líquido e da taxa interna de retorno. O empreendimento demonstrou valores positivos para a viabilidade, como o payback menor que 3 anos. A análise indicou uma taxa interna de retorno de 31, 45%, consideravelmente maior que a taxa de atratividade mínima, assim como um valor presente líquido positivo, embasando a viabilidade do empreendimento. Conclui-se que o empreendimento é viável e gera um retorno considerável para o investidor, demonstrando que o investimento traz benefícios ambientais e financeiros. Palavras-chave: Análise econômica, Sustentabilidade na construção, RCC.
INTERPRÉTER DES OEUVRES D’ART FIGURATIVES POUR ÉTUDIER DES RÉALITÉS PASSÉES : EXPLORATION DU POTENTIEL D’UN DISPOSITIF MUSÉO-TECHNO-DIDACTIQUE
Authors: Larouche Marie-Claude , Fillion Pierre-Luc , Roy Normand , Paillé Marie-Ève , Murray Jean-Luc , Boyer Patricia , Godin Geneviève 
Published: June 2018

De l’art aux sciences humaines, comment amener des élèves à tirer profit des œuvres en contexte muséal au moyen du numérique mobile ? Nous présentons la mise en place d’un projet de recherche-développement avec le Musée des beaux-arts de Montréal et des écoles primaires montréalaises visant la conception et la mise à l’essai d’un dispositif muséo-techno-didactique. Ce dispositif recourt à un prototype d’application pour les technologies mobiles que nous avons conçu pour une expérience muséale au croisement des arts visuels et des sciences humaines. Après avoir exposé la démarche de conception et la mise à l’essai du dispositif auprès de 3 classes de 3ecycle, nous explorons son potentiel pour le raisonnement en sciences humaines au contact des œuvres d’art, plus spécifiquement sous l’angle de l’interprétation d’œuvres d’art figuratives pour leur valeur documentaire. L’analyse des vidéos réalisées montre l’intérêt du dispositif pour stimuler et recueillir le raisonnement des élèves, mais démontre aussi certaines faiblesses dans la contextualisation des œuvres, possiblement liées à des connaissances limitées concernant les réalités passées étudiées.
ACTIVITÉ INTERPRÉTATIVE ET LITTÉRATURE DE JEUNESSE SUR ALBUM NUMÉRIQUE : PISTES DE RÉFLEXION POUR UNE MISE EN CONTEXTE
Authors: Perret-Truchot Laetitia 
Published: June 2018

En quoi l’album de jeunesse numérique modifie-t-il l’activité scolaire d’interprétation des textes ? Dans quelle mesure interroge-t-il la notion de lecture distanciée/lecture identificatoire ? Nous apporterons des éléments de réponse à ces questions générales en analysant les versions numérique et papier de l’album L’Herbier des fées. Nous nous interrogerons sur le dispositif didactique et notamment technodidactique permettant d’accéder à ces oeuvres multimodales et nous nous livrerons à une étude de cas à partir du livre numérique Francis et la souris verte, testé dans une classe de grande section.
L’otage, vecteur de guerre ou de paix ?
Authors: Rousseau Rivard Joëlle 
Published: June 2018

Cet article propose de réfléchir sur la façon dont s’articulent les états de guerre et de paix par le biais de la figure de l’otage, envisagée comme un espace de tensions et de négociations qui tantôt a apaisé, tantôt envenimé les conflits. Nous nous intéresserons à son évolution historique à partir de deux textes du 20e siècle dont le rapprochement s’est d’abord fait par les titres : une pièce de théâtre de Jean Giraudoux, La guerre de Troie n’aura pas lieu (1935), et un essai de Jean Baudrillard, La guerre du Golfe n’a pas eu lieu (1991).
Quand la mémoire s’en va-t’en « guerre ». Penser les marges de la commémoration des victimes du national-socialisme dans l’Allemagne du XXIe siècle
Authors: Clec’h François 
Published: June 2018

Comment penser les inégalités et les marges de la commémoration des victimes du national-socialisme dans l’Allemagne contemporaine ? Ne plus concevoir la mémoire « officielle », ni même celle des groupes de victimes comme un donné constitue une condition nécessaire à toute tentative de réponse. C’est pourquoi le présent article propose une conception plus dynamique, plus précise sans doute, en convoquant la notion de « champ » développée par Pierre Bourdieu*. L’idée est alors de dégager une intelligence relationnelle et spatiale, nécessairement interactive, de la production de la mémoire ; d’identifier les acteurs (individuels ou collectifs), les discours et les pratiques impliqués dans sa constitution ; en un mot : de considérer chaque mémoire particulière dans sa pluralité.
Evaluation of the Lamer Social Competence in Preschool Scale
Authors: Løkken Ingrid Midteide , Broekhuizen Martine Louise , Moser Thomas , Bjørnestad Elisabeth , Hegna Maren Meyer 
Published: June 2018

Abstract: The Lamer Social Competence in Preschool Scale (LSCIP) has been widely used in Norway to assess children’s social competence; however, the six-factor structure has not been validated since the scale was developed. The aim of this study is to evaluate the structure of the LSCIP using confirmatory and exploratory factor analyses. The results show that the original model has a nearly adequate fit according to model fit criteria, but also suggest the need for revisions to achieve a better model. The study contributes to the further development of the LSCIP as a measurement tool that can be used to measure children’s social competence in both research and practice.
Keywords: assessment; evaluation; Lamer Social Competence in Preschool Scale; social competence.
Three-dimensional Ultrasound Volume Measurements in an Aortic Aneurysm Model
Authors: Johnsen Lydia , Jonung Jon Anders Torbjørn , Laxdal Elin Hanna , Pedersen Gustav 
Published: June 2018

Measuring the aneurysm sac’s size is vital in postoperative surveillance following endovascular treatment of aortic aneurysms. A three-dimensional ultrasound technique may enable accurate volume measurements. However, there is no validation of any commercially available electro-mechanical 3D ultrasound equipment or of the software used when measuring the volume of the aortic aneurysm sac. This investigation used a phantom model to study a three-dimensional ultrasound technique on aortic aneurysm sac volume measurements. High volume measurement accuracy indicates that this method may be useful for postoperative surveillance following endovascular aortic aneurysm operations. These results must be confirmed in clinical studies.
aaquetzalliis required for epithelial cell polarity and neural tissue formation inDrosophila
Authors: Mendoza-Ortíz Miguel A. , Murillo-Maldonado Juan M. , Riesgo-Escovar Juan R. 
Published: June 2018

Morphogenetic movements during embryogenesis require dynamic changes in epithelial cell polarity and cytoskeletal reorganization. Such changes involve, among others, rearrangements of cell-cell contacts and protein traffic. InDrosophila melanogaster, neuroblast delamination during early neurogenesis is a well-characterized process requiring a polarized neuroepithelium, regulated by the Notch signaling pathway. Maintenance of epithelial cell polarity ensues proper Notch pathway activation during neurogenesis. We characterize hereaaquetzalli(aqz), a gene whose mutations affect cell polarity and nervous system specification. Theaqzlocus encodes a protein that harbors a domain with significant homology to a proline-rich conserved domain of nuclear receptor co-activators.aqzexpression occurs at all stages of the fly life cycle, and is dynamic.aqzmutants are lethal, showing a disruption of cell polarity during embryonic ventral neuroepithelium differentiation resulting in loss of epithelial integrity and mislocalization of membrane proteins (shown by mislocalization of Crumbs, DE-Cadherin, and Delta). As a consequence,aqzmutant embryos with compromised apical-basal cell polarity develop spotty changes of neuronal and epithelial numbers of cells.
Evaluation of sparing organs at risk (OARs) in left‐breast irradiation in the supine and prone positions and with deep inspiration breath‐hold
Authors: Saini Amitpal Singh , Hwang Catherine S. , Biagioli Matthew C. , Das Indra J. 
Published: June 2018

AbstractPurposeTo compare doses to organs at risk (OARs) for left‐sided whole‐breast radiation therapy with comparable planning target volume (PTV) coverage using three techniques: free breathing in a supine position (SFB), deep inspirational breath‐hold in a supine position (SDIBH), and free breathing in prone position (PFB).Materials and methodsThirty‐three patients with left‐sided early‐stage breast cancer underwent CT simulation following SFB, SDIBH, and PFB protocols for whole‐breast radiation therapy. One radiation oncologist contoured the breast PTV, heart, left ventricle (LV), and left anterior descending artery (LAD). Treatment plans were optimized using field‐in‐field technique with the AAA algorithm. Each plan was optimized to provide identical coverage to the PTV such that a reasonable comparison for OAR dosimetry could be evaluated. All plans were prescribed 42.56 Gy in 16 fractions to the left‐breast PTV.ResultsThe mean dose in SFB for the heart, LV, and LAD was 1.92, 3.19, and 21.73 Gy, respectively, which were significantly higher than the mean dose in SDIBH for the heart (1.08 Gy, P ≤ 0.0001), LV (1.50 Gy, P ≤ 0.0001), and LAD (6.3 Gy, P ≤ 0.0001) and in PFB for the heart (0.98 Gy, P ≤ 0.0001), LV (1.34 Gy, P ≤ 0.0001), and LAD (6.57 Gy, P ≤ 0.0001). Similar findings were noted for the cardiac components in SFB for V2.5, V5, V10, V20, and V30 compared with values in SDIBH and PFB. The mean dose for the left lung in PFB was 0.61 Gy that was significantly lower than in SFB (5.63 Gy, P ≤ 0.0001) and SDIBH (5.54 Gy, P ≤ 0.0001). Mean dose and dosimetric values for each OAR increased in SFB and SDIBH for patients with a large breast volume compared with values for patients with a small breast volume.ConclusionsSFB results in higher heart, LAD, and LV doses than the other techniques. Both PFB and SDIBH are more advantageous for these OARs irrespective of breast volume. PFB results in significantly lower lung doses than SFB and SDIBH. PFB always provided better results than SFB for the heart, LV, LAD, and lung. This conclusion contrasts with some published studies concluding that the prone position has no benefit for heart sparing.
Distributed adaptive output consensus control of a class of uncertain nonlinear multiagents systems
Authors: Yang Yang , Tan Jie 
Published: June 2018

SummaryThis paper addresses the leader‐follower output consensus problem for a class of uncertain nonlinear multiagent systems in a directed communication topology. By employing the backstepping method, the dynamic surface control technique, neutral networks, and the graph theory, a distributed adaptive control scheme is developed recursively for each follower using its own and neighbors' information. The key features of this strategy are that it reduces the computational burden by introducing the dynamic surface control approach and there is no requirement for a priori knowledge about uncertain dynamics of the system. Moreover, in theory, it is proved that the designed control approach can steer the output signals of followers in a directed graph to track the desired trajectory of the leader and guarantee all signals in the closed‐loop system cooperatively semiglobally uniformly ultimately bounded. Furthermore, two examples are included, and the simulation results demonstrate the effectiveness of the proposed strategy.
Determining the Dielectric Constants of Organic Photovoltaic Materials Using Impedance Spectroscopy
Authors: Hughes Michael P. , Rosenthal Katie D. , Ran Niva A. , Seifrid Martin , Bazan Guillermo C. , Nguyen Thuc‐Quyen 
Published: June 2018

AbstractThe photovoltaic and electrical properties of organic semiconductors are characterized by their low dielectric constant, which leads to the formation of polarons and Frenkel excitons. The low dielectric constant of organic semiconductors has been suggested to be significantly influential in geminate and bimolecular recombination losses in organic photovoltaics (OPVs). However, despite the critical attention that the dielectric constant has received in literature discussions, there has not yet been a thorough study of the dielectric constant in common organic semiconductors and how it changes when blended. In fact, there have been some inconsistent and contradictory reports on such dielectric constants, making it difficult to identify trends. Herein, at first a detailed explanation of a specific methodology to determine the dielectric constant in OPV materials with impedance spectroscopy is provided, including guidelines for possible experimental pitfalls. Using this methodology, the analysis for the dielectric constant of 17 common neat organic semiconductors is carried out. Furthermore, the relationship between the dielectric constant and blend morphology are studied and determined. It is found that the dielectric constant of a blend system can be very accurately predicted solely based on the dielectric constants of the neat materials, scaled by their respective weight ratios in the blend film.
Hydrophilic/Oleophilic Magnetic Janus Particles for the Rapid and Efficient Oil–Water Separation
Authors: Song Yongyang , Zhou Jiajia , Fan Jun‐Bing , Zhai Wenzhong , Meng Jingxin , Wang Shutao 
Published: June 2018

AbstractThe separation of microsized oil droplets from water is strongly required by the environmental protection and petroleum industry. However, the separation of microsized oil droplets from water is often ignored. Herein, magnetic Janus particles are reported with a convex hydrophilic surface/concave oleophilic surface by emulsion interfacial polymerization and selective surface assembly, realizing the rapid and efficient separation of microscaled tiny oil droplets from water. These magnetic Janus particles exhibit significant abilities to separate microscaled oil droplets from water, which usually occurs within 120 s with a separation efficiency >99%. Theoretical and experimental results demonstrate that these magnetic Janus particles can capture tiny oil droplets to make them coalesce into larger ones during the process of separation. Further studies reveal that these Janus particles can self‐assemble and closely pack onto the interface of larger oil droplets, acting as surfactants to stabilize them. Moreover, the shape effect of the Janus particle is demonstrated on the coalescence of the oil droplets.
A Simply Modified Lymphocyte for Systematic Cancer Therapy
Authors: Zheng Di‐Wei , Fan Jin‐Xuan , Liu Xin‐Hua , Dong Xue , Pan Pei , Xu Lu , Zhang Xian‐Zheng 
Published: June 2018

AbstractCytotherapy has received considerable attention in the field of cancer therapy, and various chemical or genetic methods have been applied to remold natural cells for improved therapeutic outcome of cytotherapy. A simple method to modify lymphocytes for cancer treatment by using a clinically used molecule, δ‐aminolevulinic acid (δ‐ALA), is reported here. After incubation with this molecule, tumor‐targeted lymphocytes spontaneously synthesize anti‐neoplastic drug protoporphyrin X (PpIX), and specifically accumulate in cancer tissue. Under periodic 630 nm laser irradiation, lymphocytes generate vesicle‐like apoptotic body (Ab) containing the above‐produced PpIX, and the facilitated delivery of PpIX from Ab makes an excellent therapeutic effect for Ras‐mutated cancer cells under a second irradiation. Importantly, a microfluidic device is further fabricated to simplify cell sorting and drug synthesis with a one‐step operation, which could promote generalization of this strategy. In vitro and in vivo studies confirm the success of such an easy‐operated and global‐regulated strategy for cancer therapy.
Side‐Chain Impact on Molecular Orientation of Organic Semiconductor Acceptors: High Performance Nonfullerene Polymer Solar Cells with Thick Active Layer over 400 nm
Authors: Luo Zhenghui , Sun Chenkai , Chen Shanshan , Zhang Zhi‐Guo , Wu Kailong , Qiu Beibei , Yang Changduk , Li Yongfang , Yang Chuluo 
Published: June 2018

AbstractA new n‐type organic semiconductor (n‐OS) acceptor IDTPC with n‐hexyl side chains is developed. Compared to side chains with 4‐hexylphenyl counterparts (IDTCN), such a design endows the acceptor of IDTPC with higher electron mobility, more ordered face‐on molecular packing, and lower band gap. Therefore, the IDTPC‐based polymer solar cells (PSCs) with a newly developed wide bandgap polymer PTQ10 as donor exhibit the maximum power conversion efficiency (PCE) of 12.2%, a near 65% improvement in PCE relative to the IDTCN‐based control device. Most importantly, the IDTPC‐based device is insensitive to the thickness of the active layer from 70 to 505 nm, which still gives a PCE of 10.0% with the active‐layer thickness of 400 nm. To the best of the authors' knowledge, a PCE of 10.0% is the highest value for the nonfullerene PSCs with an active layer thicker than 400 nm. These results reveal that the blend of PTQ10 and IDTPC exhibits great potential for highly efficient nonfullerene PSCs and large‐area device fabrication.
Rational Design of a Dual‐Function Hybrid Cathode Substrate for Lithium–Sulfur Batteries
Authors: Luo Liu , Chung Sheng‐Heng , Manthiram Arumugam 
Published: June 2018

AbstractA unique 3D hybrid sponge with chemically coupled nickel disulfide‐reduced graphene oxide (NiS2‐RGO) framework is rationally developed as an effective polysulfide reservoir through a biomolecule‐assisted self‐assembly synthesis. An optimized amount of NiS2 (≈18 wt%) with porous nanoflower‐like morphology is uniformly in situ grown on the RGO substrate, providing abundant active sites to adsorb and localize polysulfides. The improved polysulfide adsorptivity from sulfiphilic NiS2 is confirmed by experimental data and first‐principle calculations. Moreover, due to the chemical coupling between NiS2 and RGO formed during the in situ synthesis, the conductive RGO substrate offers a 3D electron pathway to facilitate charge transfer toward the NiS2‐polysulfide adsorption interface, triggering a fast redox kinetics of polysulfide conversion and excellent rate performance (C/20–4C). Therefore, the self‐assembled hybrid structure simultaneously promotes static polysulfide‐trapping capability and dynamic polysulfide‐conversion reversibility. As a result, the 3D porous sponge enables a high sulfur content (75 wt%) and a remarkably high sulfur loading (up to 21 mg cm−2) and areal capacity (up to 16 mAh cm−2), exceeding most of the reported values in the literature involving either RGO or metal sulfides/other metal compounds (sulfur content of <60 wt% and sulfur loading of <3 mg cm−2).
Austausch der Proteinkontaktflächen in der homodimeren tRNA‐Guanin‐Transglycosylase: ein Weg der funktionellen Regulation
Authors: Ehrmann Frederik Rainer , Kalim Jorna , Pfaffeneder Toni , Bernet Bruno , Hohn Christoph , Schäfer Elisabeth , Botzanowski Thomas , Cianférani Sarah , Heine Andreas , Reuter Klaus , Diederich François , Klebe Gerhard 
Published: June 2018

AbstracttRNA‐Guanin‐Transglycosylase, ein Target zur Therapie der Shigellen‐Ruhr, erkennt tRNA nur als Homodimer und führt einen kompletten Nucleobasen‐Austausch an dessen Wobble‐Position durch. Inhibitoren des aktiven Zentrums blockieren die Enzymfunktion durch kompetitive Verdrängung der tRNA. In Lösung dissoziiert der homodimere Wildtyp nur geringfügig, während mutierte Varianten eine erhebliche Monomerisierung in Lösung aufzeigen. Ein Inhibitor transformiert das Protein in einen verdrehten Zustand, wobei eine Monomereinheit um etwa 130° rotiert. In dieser veränderten Geometrie ist das Enzym nicht länger in der Lage, die tRNA zu binden und zu prozessieren. Drei Zucker‐basierte Inhibitoren wurden entworfen und synthetisiert, die das Protein sowohl im funktionell kompetenten als auch im verdrehten inaktiven Zustand binden. Beide Zustände kristallisieren unter identischen Bedingungen nebeneinander im selben Kristallisationsgefäß. Möglicherweise entspricht die verdrehte inaktive Form mit einem Ruhezustand des Enzyms, der wichtig für dessen funktionelle Regulation sein könnte.
Radikalische Trifluormethoxylierung aromatischer Verbindungen durch photochemische N‐O‐Bindungsaktivierung
Authors: Jelier Benson J. , Tripet Pascal F. , Pietrasiak Ewa , Franzoni Ivan , Jeschke Gunnar , Togni Antonio 
Published: June 2018

AbstractEine einfache Methode für die Trifluormethoxylierung nicht funktionalisierter C‐H‐Bindungen bietet Zugang zu aromatischen Trifluoromethylethern. Die lichtgetriebene Reaktion unterscheidet sich von herkömmlichen Prozessen, indem das OCF3‐Radikal durch eine photoredoxkatalytische N‐O‐Bindungsfragmentierung generiert wird. Das entsprechende Pyridinium‐basierte Reagenz ist stabil und ermöglicht einen einfachen Zugang zu verschiedenen Verbindungen der oben genannten Klasse.
A new xanthene‐based two‐photon fluorescent probe for the imaging of 1,4‐dithiothreitol (DTT) in living cells
Authors: Wang Chao , Dong Baoli , Kong Xiuqi , Zhang Nan , Song Wenhui , Lin Weiying 
Published: June 2018

Abstract1,4‐Dithiothreitol (DTT) has wide applications in cell biology and biochemistry. Development of effective methods for monitoring DTT in biological systems is important for the safe handling and study of toxicity to humans. Herein, we describe a two‐photon fluorescence probe (Rh‐DTT) to detect DTT in living systems for the first time. Rh‐DTT showed high selectivity and sensitivity to DTT. Rh‐DTT can be successfully used for the two‐photon imaging of DTT in living cells, and also can detect DTT in living tissues and mice.
Batch versus Continuous Flow Performance of Supported Mono‐ and Bimetallic Nickel Catalysts for Catalytic Transfer Hydrogenation of Furfural in Isopropanol
Authors: Wang Yantao , Prinsen Pepijn , Triantafyllidis Konstantinos S. , Karakoulia Stamatia A. , Yepez Alfonso , Len Christophe , Luque Rafael 
Published: June 2018

AbstractFurfural takes an important position in hemicelluloses biorefinery platforms. It can be converted into a wide range of chemicals. One important valorization route is the catalytic hydrogenation. Whereas molecular hydrogen is mostly used in industrial hydrogenation processes, recent studies also showed that alcohols can be used as reductants from which hydrides can be transferred catalytically to furfural. This process is often assisted by the formation of significant amounts of side products, in despite of high yields to the hydrogenolysis product 2‐methylfuran. The present work explores the catalytic behavior in batch and continuous flow of mono‐ and bimetallic nickel catalysts supported on activated carbon for the catalytic transfer hydrogenation of furfural in isopropanol.