bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sektör Düzeyinde Rekabet Edebilirlik ve Dünya Talebine Uyum: Türkiye ve Seçili Ülkeler için Bir Analiz
Authors: AYTUN Uğur , KILIÇASLAN Yılmaz 
Published: April 2018

Bu
çalışmada seçili on sekiz ülkenin farklı teknoloji yoğunluklarındaki alt
endüstrilerinin ticaretinin ihracat payı performanslarını, bunların dünya ticaret payları ile karşılaştırarak
görmeye çalışmamıza imkân veren Sabit Pazar Payı analizi ile irdeledik. BACI
dış ticaret veri tabanının 1995-2014 dönemini kapsayan bulguları, düşük, orta
ve yüksek teknolojili endüstrilerde birçok gelişmekte olan ülkenin pazar
paylarını, kendi çabaları, yani rekabet edebilirlik etkisi yoluyla hızlı bir
biçimde artırdığını göstermektedir. ABD, Japonya ve Almanya başta olmak üzere,
yüksek gelirli ülkeler cephesinde de bu pazar payları ya azalmakta ya da
durağan bir konumdadır. Bu iki bulgu küresel değer zincirlerinin yayılması
sonucunda üretim sürecindeki birçok aşamanın gelişmiş ülkelerden gelişmekte
olan ülkelere kaydığı şeklinde yorumlanabilir. Öte yandan, Vietnam ve bir
dereceye kadar da Çin bu süreçte dünyada talebi artan mallarda da rekabet
edebilirliklerini güçlü bir şekilde artırabilmiş ve toplam ihracat bakımından
yüksek bir yakınsama performansı gösterebilmişlerdir.
GERENCIAMENTO DE PROJETOS EM RECURSOS HÍDRICOS (SUBTERRÂNEOS): UMA PROPOSTA COM USO DO PMBOK
Authors: Ribeiro Daniela Dantas de Menezes 
Published: April 2018

O presente artigo tem como objetivo aplicar os processos apresentados no PMBOK na elaboração e gerenciamento de projetos sobre águas subterrâneas no Estado de Sergipe. A água subterrânea consiste em uma importante reserva hídrica, com ocorrência abaixo da superfície terrestres, ocupando os poros e vazios entre os grãos das rochas sedimentares e fraturas de rochas maciças, sendo armazenadas em reservatórios denominados aquíferos. A Lei Federal n° 9433/97(BRASIL, 1997) instituiu a Política Nacional de Recursos Hídricos e o Sistema de Gerenciamento de Recursos Hídricos, e possui como seus instrumentos o Sistema Nacional de Informações sobre Recursos Hídricos e a Outorga de Direito de Uso de Recursos Hídricos. Esses instrumentos possuem significativa importância na gestão dos recursos hídricos subterrâneos, uma vez que requer para suas aplicações, estudos de caracterização do sistema aquífero visando um melhor aproveitamento do reservatório de acordo com seus diferentes usos (abastecimento humano, industrial e irrigação). A abordagem metodológica contemplará os seguintes processos com base no PMBOK: iniciação, planejamento, execução, monitoramento e controle e encerramento. Como também a elaboração de um modelo do projeto Canvas com aplicação em estudo sobre monitoramento de águas subterrâneas considerando a unidade de planejamento de gestão (bacia hidrográfica) no município.
A comparative study of adult and pediatric polysomnography
Authors: K. Athiyaman , M. Gowri Shankar , G. Suji , D. Prabhu 
Published: April 2018

<p class="abstract"><strong>Background:</strong> Obstructive sleep apnea (OSA) also referred to as obstructive sleep apnea-hypopnea-is a sleep disorder that involves cessation or significant decrease in airflow in the presence of breathing effort. It is the most common type of sleep-disordered breathing and is characterized by recurrent episodes of upper airway collapse during sleep. Pediatric obstructive sleep apnea syndrome (OSAS), like adult OSAS, is characterized by intermittent upper airway collapse during sleep and is associated with anatomic and neuromuscular factors. However, the clinical manifestations, diagnostic criteria, and polysomnographic findings of OSAS in children are likely to be different from those in adults. Adult OSA and pediatric OSA though the pathogenesis is more or less same, the evaluation gives a significant difference in outcome.</p><p class="abstract"><strong>Methods:</strong> 60 patients who meet the inclusion criteria were subjected to clinical evaluation and level 1 sleep study was done. </p><p class="abstract"><strong>Results:</strong> Mean age group in adults was 39.86±8.42 yrs the most common cause in adults being obesity and the mean age group in pediatric was 7.63±1.71 yrs with adenotonsillar hypertrophy being the commonest cause. The gender distribution among affected is predominantly being male both in adults and in the pediatric population. The lowest mean desaturation was 81% in adults as compared to 73.23% in children.</p><p class="abstract"><strong>Conclusions:</strong> Significant PSG findings were noted in gender distribution and in Mean desaturation, AHI in both adults and pediatric population.</p>
Preliminary investigation of a novel endodôntico obturator
Authors: Kalman Les , Lui Carol 
Published: April 2018

Conventional endodontic treatment requires the removal of the pulp and dentin by shaping the inside of the tooth. The shaping occurs with the use of drills to a geometry that is directly related to a predetermined form of material that will obturate the tooth’s interior.The aim of this study was to investigate a novel device that applies sonic energy during the obturation of the tooth’s interior. Extracted human teeth underwent endodontic treatment. Half of the group were conventionally obturated and the other half were obturated with the novel device. Post-treatment radiographs were evaluated utilizing Schulich dental school endodontic marking criteria.No statistical significance (α = 0.05) was determined between each group. A higher incidence of filled space (60%) occurred with sonic obturation when compared to conventional obturation (33%). Micro-computer tomography (CT) images were obtained of one sample from each group to assess the three-dimensional obturation. The novel device facilitated easy handling and demonstrated potential for effective obturation. Further tests are required for device refinement, larger sample sizes and clinical validation to assess the attitude and practice of dental professionals towards using of advance Radiographic technique.
INFLUÊNCIA DO SISTEMA DE CONTROLE ORÇAMENTÁRIO SOBRE A CAPACIDADE ABSORTIVA
Authors: Nascimento Sabrina , Amorim Bianca Costa , Penz Daniel , Dalbosco Inocencia Boita , Silveira Amelia 
Published: April 2018

Esta pesquisa buscou analisar a influência da capacidade absortiva no sistema de controle orçamentário das empresas incubadas na mesorregião do oeste de Santa Catarina (SC). A amostra teve 29 empresas que responderam o instrumento de autopreenchimento durante o primeiro semestre de 2016. A pesquisa survey, com método quantitativo, na análise dos dados utilizou a técnica de Modelagem de Equações Estruturais (MEE) com SEM-PLS. Os resultados apontam que o relacionamento entre Sistema de Controle Orçamentário e a Capacidade de Absorção ocorre na taxa de 33%, o modelo apresenta uma relação significante estatisticamente, de acordo com Hair Jr et al. (2014).
A question on sustainability of drinking water supply: a district level analysis of India using analytic hierarchy process
Authors: Poonia Anamika , Punia Milap 
Published: April 2018

Abstract
The subject of drinking water supply falls under the legislative jurisdiction of the State governments in India. States have their own mechanism of drinking water supply through urban and rural local bodies. Drinking water supply itself is a multidimensional phenomenon of sources, quality, accessibility, sufficiency, etc. This study combines various aspects of drinking water supply at the district level, by assigning weights through analytic hierarchy process, to result in a drinking water supply index. The spatial pattern of drinking water supply index is not in favor of the areas having abundant natural water endowment. Areas which are low in the natural endowment of water are better in drinking water supply, while areas which have abundant natural water are not able to manage the available water and are low on the drinking water supply index. Among various socio-economic-political factors, water governance is most important in the wake of water supply being the function of urban and rural local bodies.
Monitoring seasonal variations of colored dissolved organic matter for the Saginaw River based on Landsat-8 data
Authors: Chen Jiang , Zhu Weining , Zheng Yuhan , Tian Yong Q. , Yu Qian 
Published: April 2018

Abstract
Remote sensing is an effective tool for studying CDOM (colored dissolved organic matter) variations and its relevant environmental factors. Monitoring CDOM distribution and dynamics in small water is often limited by the coarse spatial resolution of traditional ocean color sensors. In this study, because of its high spatial resolution of 30 m, Landsat-8 data were used to assess seasonal variations of CDOM in the Saginaw River, by using an empirical statistic model. Pearson correlation analysis between CDOM variations and other environmental factors, such as temperature, discharge, and dissolved oxygen, shows that temperature was negatively correlated to CDOM variations and discharge played a positive role. We also calculated the monthly mean aCDOM(440) (the absorption coefficient of CDOM at 440 nm) for the Saginaw River between April and November from 2013 to 2016. This study demonstrates a good example for future applications in small waters: observing CDOM variations and other relevant environmental factors change by using Landsat remote sensing, so that we can know more about water quality and ecosystem health of small waters as well as the climate change impact on regional watersheds.
Neoadjuvant Therapy is Essential for Resectable Pancreatic Cancer
Authors: Xu Jin-Zhi , Wang Wen-Quan , Zhang Shi-Rong , Xu Hua-Xiang , Wu Chun-Tao , Qi Zi-Hao , Gao He-Li , Li Shuo , Ni Quan-Xing , Yu Xian-Jun , Liu Liang 
Published: April 2018

Background:
Awareness of the benefits of neoadjuvant therapy is increasing, but its use as an
initial therapeutic option for patients with resectable pancreatic cancer remains controversial, especially
for those patients without high-risk prognostic features. Even for patients with high-risk features who are
candidates to receive neoadjuvant therapy, no standard regimen exists.

Methods:
In this review, we examined available data on the neoadjuvant therapy in patients with resectable
pancreatic cancer, including prospective studies, retrospective studies, and ongoing clinical trials,
by searching PubMed/MEDLINE, ClinicalTrials.gov, Web of Science, and Cochrane Library. The characteristics
and results of screened studies were described.

Results:
Retrospective and prospective studies with reported results and ongoing randomized studies were
included. For patients with resectable pancreatic cancer, neoadjuvant therapy provides benefits such as
increased survival, decreased risk of comorbidities and mortality, and improved cost-effectiveness due to
an increased completion rate of multimodal treatment. Highly active regimens such as FOLFIRINOX (folinic
acid, fluorouracil, irinotecan, and oxaliplatin) or gemcitabine plus nab-paclitaxel are considered acceptable
therapeutic regimens. Additionally, platinum-containing regimens other than FOLFIRINOX are
acceptable for selected patients. Other therapies, such as chemoradiation treatment, immuno-oncology
agents, and targeted therapies are being explored and the results are highly anticipated.

Conclusion:
This review highlights the benefits of neoadjuvant therapy for resectable pancreatic cancer.
Some regimens are currently acceptable, but need more evidence from well-designed clinical trials or
should be used after being carefully examined by a multidisciplinary team.
Antitumor Effect of Pomolic Acid in Acute Myeloid Leukemia Cells Involves Cell Death, Decreased Cell Growth and Topoisomerases Inhibition
Authors: Pereira Michelle X.G. , Hammes Amanda S.O. , Vasconcelos Flavia C. , Pozzo Aline R. , Pereira Thaís H. , Caffarena Ernesto R. , Gattass Cerli R. , Maia Raquel C. 
Published: April 2018

Background:
Acute myeloid leukemia (AML) represents the largest number of annual deaths from
hematologic malignancy. In the United States, it was estimated that 21.380 individuals would be diagnosed with
AML and 49.5% of patients would die in 2017. Therefore, the search for novel compounds capable of increasing
the overall survival rate to the treatment of AML cells is urgent.

Objectives:
To investigate the cytotoxicity effect of the natural compound pomolic acid (PA) and to explore the
mechanism of action of PA in AML cell lines with different phenotypes.

Methods:
Three different AML cell lines, HL60, U937 and Kasumi-1 cells with different mechanisms of resistance
were used to analyze the effect of PA on the cell cycle progression, on DNA intercalation and on human
DNA topoisomerases (hTopo I and IIα) in vitro studies. Theoretical experiments of the inhibition of hTopo I and
IIα were done to explore the binding modes of PA.

Results:
PA reduced cell viability, induced cell death, increased sub-G0/G1 accumulation and activated
caspases pathway in all cell lines, altered the cell cycle distribution and inhibited the catalytic activity of both
human DNA topoisomerases.

Conclusion:
Finally, this study showed that PA has powerful antitumor activity against AML cells, suggesting
that this natural compound might be a potent antineoplastic agent to improve the treatment scheme of this
neoplasm.
Investigasi Forensik pada Kasus Kematian Dugaan Akibat Cedera Kepala
Authors: Afandi Dedi , Herkutanto Herkutanto 
Published: April 2018

Autopsi diperlukan dalam upaya menentukan penyebab kematian dan cara kematian. Autopsi seringkali tidak dapat dilakukan karena penolakan oleh keluarga. Laporan kasus ini menyajikan investigasi forensik pada kasus kematian yang diduga akibat cedera kepala pada korban yang telah dikremasi. Investigasi pada tempat kejadian meninggal, perhitungan indikator efek trauma pada kepala dan studi literatur dilakukan untuk membuktikan probabilitas kematian akibat cedera kepala dan probabilitas kemungkinan penyebab kematian pada korban.Â Dari metode tersebut didapatkan probabilitas terjadinya cedera otak traumatik ringan adalah 8,33% dan probalitas kematian jantung mendadak 80,95%. Kasus ini menunjukkan pentingnya memahami aspek medikolegal trauma, memahami biomekanika trauma dan melakukan investigasi forensik.
Linguagem e mudança social na perspectiva da Análise Crítica do Discurso: a extensão universitária enquanto espaço de diálogo e (re)significação de saberes (Language and social change …)
Authors: Souza Antonio Escandiel , Costa Aline Aparecida Cezar 
Published: April 2018

Este artigo apresenta algumas reflexões acerca da extensão universitária como espaço dialógico de construção de conhecimentos e contextualiza a universidade enquanto espaço de mudança das práticas sociais. Apresenta a extensão universitária como potência para práticas dialógicas de aprendizagem e forma de inspirar novas possibilidades para mudança e transformação social. Busca explicitar a linguagem pela perspectiva multidimensional e dialética do discurso, tendo por base a teoria da análise Crítica de Discurso (ACD), de Fairclough (2001).Também traz a concepção freireana, para o qual diálogo é um princípio educativo emancipador que promove no pensar crítico, na ação-reflexão, a mudança e transformação de mundo.
Transformación de las prácticas de aula en la escuela para la construcción del hábito lector
Authors: Baquero Silva María Ligia , Doria Correa Rudy 
Published: April 2018

La presente investigación se desarrolló en la Institución Educativa Rafael Núñez del Municipio de Sincelejo, atendiendo a un enfoque cualitativo y siguiendo una metodología de Investigación Acción Participativa, a fin de generar hábitos de lectura a partir de estrategias que posibiliten una transformación práctica por parte de los docentes. La población de estudio estuvo conformada por 5 docentes y 116 estudiantes de básica primaria. Se cumplieron 3 fases secuenciales la primera denominada fase de indagación diagnóstica; la segunda, fase de planificación y acción y por último una fase de evaluación. Como uno de los logros más importantes del presente estudio se relaciona la reflexión efectuada por parte de los GET que permitió analizar y mejorar el proceso formativo en la escuela, llevando consecuentemente a una dinamización de las clases, obteniéndose un hábito lector más por motivación que por obligación curricular; y la práctica consensuada de estrategias didácticas por parte de los maestros investigadores, para la construcción y sostenibilidad de dicho hábito.
Análisis comparado sobre el concepto de tutela judicial efectiva entre los países de Colombia y España
Authors: Heras Ramos Luis Ernesto 
Published: April 2018

En el presente artículo de reflexión se analizará la posibilidad de establecer si en el plano de la justicia efectivamente se presenta la tutela judicial efectiva, por ser un tema relacionado con la administración de justicia y por cuanto la tutela se asocia directamente con los derechos fundamentales de la persona, especialmente la vida, dejando a un lado otro de los derechos fundamentales como es el de la justicia, porque implica quiérase o no de la vida de las personas. Se desarrolló este estudio para determinar la realidad de la tutela judicial efectiva, para ello se realiza un análisis comparado teniendo presente el país de España por tratarse de uno de los más avanzados en el tema. Se basa en los principios estipulados de la tutela judicial la cual se remonta a varios siglos. Metodológicamente se aplicó un tipo de estudio descriptivo - exploratorio, además de con la técnica cualitativa sin abandonar el paradigma de investigación sociojurídica. Se aplica el método deductivo, al ir estudiando comparando para llegar a una conclusión general.

Palabras Claves:

Derecho fundamental, juez, ley, persona.
Principio de transparencia en la contratación pública en el distrito de Cartagena, D. T. Y C.
Authors: Buelvas Mendoza Milton 
Published: April 2018

El presente artículo de reflexión tiene como propósito analizar las contradicciones y desajustes al sistema de Contratación Estatal colombiano, en el marco de nuestro Sistema y Régimen Políticos, abordando un análisis que permita entender el tema de Gobernabilidad, Democracia, instituciones, normativas, sociedad, cultura política, participación, cuando de enfrentar la corrupción se trate. Asimismo, se abordara la experiencia que tuvo el sector descentralizado de Cartagena D. T. y C., durante el periodo 2008 al 2011,como forma de conocimiento de la inspección, vigilancia, visión ciudadana y control de la gestión en el periodo mencionado, Las conclusiones a las que llega el presente documento, pueden ser punto de partida para entender mucho mejor la problemática, y encontrar posibles soluciones: Instituciones fuertes, gobernabilidad, normativas, participación proactiva y consciente de la sociedad civil.
Auditor Independence in the United States: Cornerstone of the Profession or Thorn in Our Side?
Authors: Church Bryan K. , Jenkins J. Gregory , Stanley Jonathan D. 
Published: April 2018

SYNOPSIS
The objective of this paper is to provide a systematic evaluation of independence as a foundational element of the auditing profession. We maintain that while independence is a theoretically appealing construct, it is fraught with practical problems surrounding its implementation, monitoring, and regulation. We analyze the current oversight of auditor independence and evaluate the need for auditor independence from the perspective of information users and information producers. In the process, we discuss important implications and intractable challenges that affect one or more parties involved in the financial-reporting process. Finally, we carefully evaluate alternatives to the current regulatory approach for managing auditor independence (i.e., proscribing various auditor-client relationships). We conclude that increasing audit committees' responsibilities for monitoring the auditor's independence—along with additional disclosure about threats and safeguards to auditor independence—is worthy of further consideration and debate as a path toward addressing the auditor independence conundrum.
Trichuris vulpis and T. trichiura infections among schoolchildren of a rural community in northwestern Thailand: the possible role of dogs in disease transmission
Authors: Areekul Pannatat , Putaporntip Chaturong , Pattanawong Urassaya , Sitthicharoenchai Prasert , Jongwutiwes Somchai 
Published: April 2018

Abstract
Background: Trichuriasis is an important soil-transmitted helminth infection caused by Trichuris trichiura. About one-tenth of the world population may be infected. Incidentally, T. vulpis or dog whipworm has been reported to infect humans based on the egg size. However, an overlapping egg dimension occurs between T. trichiura and T. vulpis leading to the potential for misdiagnosis. Objective: Develop a PCR method to differentiate T. trichiura and T. vulpis eggs in stool samples and to investigate the prevalence of both whipworms in humans and dogs in a rural community in Thailand. Materials and methods: We determined and compared the small subunit ribosomal RNA sequences of both species of whipworms for developing species-specific PCR diagnosis. After validation of the method, we conducted a cross-sectional survey at Ta Song Yang District in Tak Province, northwestern Thailand in 2008. Stool samples were randomly recruited from 80 schoolchildren (36 males, 44 females) and 79 dogs in this community. Results: Fifty-six individuals harbored Trichuris eggs in their stools. The PCR-based diagnosis revealed that 50 cases were infected with T. trichiura and six (10.7%) were co-infected with both T. trichiura and T. vulpis. Although the dimension of Trichuris eggs provided some diagnostic clues for species differentiation, a remarkable variation in the length of these whipworm eggs was observed among samples that could lead to misdiagnosis. Conclusion: Both T. trichiura and T. vulpis eggs were detected in stool samples of dogs that roamed around this community, highlighting the potential reservoir role of dogs in the transmission of both human and dog whipworms in this population.
Stem cell factor in gingival crevicular fluid in periodontal health and disease
Authors: Honsawek Sittisak , Unwerawattana Wannee 
Published: April 2018

Abstract
Background: Stem cell factor is a pleiotropic cytokine produced by several cell types including fibroblasts, bone marrow stromal cells, mast cells, and endothelial cells. In addition, stem cell factor is an important hematopoietic growth factor, which binds to and activates the ligand for the tyrosine kinase-type receptor c-kit. Objectives: Analyze concentration of stem cell factor within gingival crevicular fluid (GCF) in both periodontal health and disease and to determine the correlation of stem cell factor in GCF and inflammatory status of periodontal tissues. Materials and methods: Forty-five subjects (aged 24 to 75 years) were classified into the following three groups according to their periodontal tissue status as group I (clinically healthy gingiva with no loss of attachment), group II (gingivitis with no attachment loss), and group III (periodontitis). GCF samples collected from each patient were examined for stem cell factor level using enzyme-linked immunosorbant assay. Results: The maximum level of stem cell factor in GCF was obtained for group III (71.8±7.8 pg/g protein), and the lowest mean stem cell factor concentration in GCF was observed for group I (22.1±7.3 pg/g protein). The GCF stem cell factor level of patients in group III was statistically higher than that in group II (p <0.04) and group I (p <0.001). In addition, the mean GCF levels of stem cell factor in group II (48.1±7.5 pg/g protein) were significantly higher than those in group I (p <0.02). There was a positive correlation between stem cell factor in GCF and gingival inflammation index (r=0.59, p <0.001) Conclusion: GCF levels of stem cell factor increased in parallel with the severity of periodontal disease. Its levels in GCF could be potentially useful as a biochemical marker of periodontal inflammation and the host response.