Shifting the limits in wheat research and breeding using a fully annotated reference genome
Authors:   The International Wheat Genome Sequencing Consortium (IWGSC), Appels Rudi , Eversole Kellye , Stein Nils , Feuillet Catherine , Keller Beat , Rogers Jane , Pozniak Curtis J. , Choulet Frédéric , Distelfeld Assaf , Poland Jesse , Ronen Gil , Sharpe Andrew G. , Barad Omer , Baruch Kobi , Keeble-Gagnère Gabriel , Mascher Martin , Ben-Zvi Gil , Josselin Ambre-Aurore , Himmelbach Axel , Balfourier François , Gutierrez-Gonzalez Juan , Hayden Matthew , Koh ChuShin , Muehlbauer Gary , Pasam Raj K. , Paux Etienne , Rigault Philippe , Tibbits Josquin , Tiwari Vijay , Spannagl Manuel , Lang Daniel , Gundlach Heidrun , Haberer Georg , Mayer Klaus F. X. , Ormanbekova Danara , Prade Verena , Šimková Hana , Wicker Thomas , Swarbreck David , Rimbert Hélène , Felder Marius , Guilhot Nicolas , Kaithakottil Gemy , Keilwagen Jens , Leroy Philippe , Lux Thomas , Twardziok Sven , Venturini Luca , Juhász Angéla , Abrouk Michael , Fischer Iris , Uauy Cristobal , Borrill Philippa , Ramirez-Gonzalez Ricardo H. , Arnaud Dominique , Chalabi Smahane , Chalhoub Boulos , Cory Aron , Datla Raju , Davey Mark W. , Jacobs John , Robinson Stephen J. , Steuernagel Burkhard , van Ex Fred , Wulff Brande B. H. , Benhamed Moussa , Bendahmane Abdelhafid , Concia Lorenzo , Latrasse David , Bartoš Jan , Bellec Arnaud , Berges Hélène , Doležel Jaroslav , Frenkel Zeev , Gill Bikram , Korol Abraham , Letellier Thomas , Olsen Odd-Arne , Singh Kuldeep , Valárik Miroslav , van der Vossen Edwin , Vautrin Sonia , Weining Song , Fahima Tzion , Glikson Vladimir , Raats Dina , Číhalíková Jarmila , Toegelová Helena , Vrána Jan , Sourdille Pierre , Darrier Benoit , Barabaschi Delfina , Cattivelli Luigi , Hernandez Pilar , Galvez Sergio , Budak Hikmet , Jones Jonathan D. G. , Witek Kamil , Yu Guotai , Small Ian , Melonek Joanna , Zhou Ruonan , Belova Tatiana , Kanyuka Kostya , King Robert , Nilsen Kirby , Walkowiak Sean , Cuthbert Richard , Knox Ron , Wiebe Krysta , Xiang Daoquan , Rohde Antje , Golds Timothy , Čížková Jana , Akpinar Bala Ani , Biyiklioglu Sezgi , Gao Liangliang , N’Daiye Amidou , Kubaláková Marie , Šafář Jan , Alfama Françoise , Adam-Blondon Anne-Françoise , Flores Raphael , Guerche Claire , Loaec Mikaël , Quesneville Hadi , Condie Janet , Ens Jennifer , Maclachlan Ron , Tan Yifang , Alberti Adriana , Aury Jean-Marc , Barbe Valérie , Couloux Arnaud , Cruaud Corinne , Labadie Karine , Mangenot Sophie , Wincker Patrick , Kaur Gaganpreet , Luo Mingcheng , Sehgal Sunish , Chhuneja Parveen , Gupta Om Prakash , Jindal Suruchi , Kaur Parampreet , Malik Palvi , Sharma Priti , Yadav Bharat , Singh Nagendra K. , Khurana Jitendra P. , Chaudhary Chanderkant , Khurana Paramjit , Kumar Vinod , Mahato Ajay , Mathur Saloni , Sevanthi Amitha , Sharma Naveen , Tomar Ram Sewak , Holušová Kateřina , Plíhal Ondřej , Clark Matthew D. , Heavens Darren , Kettleborough George , Wright Jon , Balcárková Barbora , Hu Yuqin , Salina Elena , Ravin Nikolai , Skryabin Konstantin , Beletsky Alexey , Kadnikov Vitaly , Mardanov Andrey , Nesterov Michail , Rakitin Andrey , Sergeeva Ekaterina , Handa Hirokazu , Kanamori Hiroyuki , Katagiri Satoshi , Kobayashi Fuminori , Nasuda Shuhei , Tanaka Tsuyoshi , Wu Jianzhong , Cattonaro Federica , Jiumeng Min , Kugler Karl , Pfeifer Matthias , Sandve Simen , Xun Xu , Zhan Bujie , Batley Jacqueline , Bayer Philipp E. , Edwards David , Hayashi Satomi , Tulpová Zuzana , Visendi Paul , Cui Licao , Du Xianghong , Feng Kewei , Nie Xiaojun , Tong Wei , Wang Le 
Published: August 2018

Insights from the annotated wheat genomeWheat is one of the major sources of food for much of the world. However, because bread wheat's genome is a large hybrid mix of three separate subgenomes, it has been difficult to produce a high-quality reference sequence. Using recent advances in sequencing, the International Wheat Genome Sequencing Consortium presents an annotated reference genome with a detailed analysis of gene content among subgenomes and the structural organization for all the chromosomes. Examples of quantitative trait mapping and CRISPR-based genome modification show the potential for using this genome in agricultural research and breeding. Ramírez-Gonzálezet al.exploited the fruits of this endeavor to identify tissue-specific biased gene expression and coexpression networks during development and exposure to stress. These resources will accelerate our understanding of the genetic basis of bread wheat.Science, this issue p.eaar7191; see also p.eaar6089