bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the Hindfoot Alignment Measured in 3D After a Medializing Calcaneal Osteotomy Using a Pre- and Postoperative Weightbearing CT
Authors: Burssens Arne , Barg Alexej , Leenders Timothy , Clockaerts Stefan , Burssens Peter , Victor Jan 
Published: September 2018

Category: Hindfoot Introduction/Purpose: An adult acquired flat foot (AAFD) is a complex 3D deformity. A medializing calcaneal osteotomy (MCO) is a surgical procedure frequently performed to correct the valgus alignment of the hindfoot in a stage II AAFD, when conservative measurements fail. However currently little is known on its accurate influence regarding the hindfoot alignment (HA). The aim is therefore to assess the influence of a MCO on the 3D HA using computer aided software analysis of the images retrieved from a weightbearing cone beam CT (WBCT). Methods: Twelve patients with a mean age of 49,4 years (range 18-67yrs) were prospectively included in a pre-post study design. Indications for surgical correction by a MCO with a solitary translation consisted of an AAFD stage II (N=10) and a posttraumatic valgus deformity (N=2). Fixation of the osteotomy was performed by a step-plate or double screw. WBCT was obtained pre- and post-operative. Images were subsequently segmented to allow a HA calculation in 3D(HA3D) by an angle between the anatomical tibia axis and the axis connecting the computed inferior calcaneuspoint and the centroid of the talus in the coronal plane based on a Cartesian coordinatesystem(Fig 1A, C). The tibia in the HA3D was separately assessed by the anatomical tibia axis (TAx 3D) and the axis to determine the tibial rotation(TR 3D) in the axial plane by connecting the computed most outer point of the anterior and posterior tubercle of the incisura fibularis(Fig 2A, D). Results: The mean medial translation of the calcaneal osteotomy during surgery was 5.72 mm (SD = 3.9). The mean HA3D pre-operatively equaled 18.21 degrees of valgus (SD = 6.6) and post-operatively 9.31 degrees of valgus (SD = 6.18). The Paired Student’s t-test showed a significant correction of 8.89 degrees (95%CI [5.99, 11.80], P<0.001). The mean TAX 3D pre-operatively was 6.80 degrees of valgus (SD = 3.38) and post-operatively 4.11 degrees of valgus (SD = 2.77), with a significant difference of 2.69 degrees (95%CI [1.79, 3.59], P <0.001). The mean TR3D pre-operatively was -27.11 degrees (SD = 4.77) and post-operatively - 28.80 degrees (SD = 5.98) and showed a significant difference of 1.69 degrees (95%CI [0.41, 2.97], P = 0,016). Conclusion: This study shows an effective correction of the valgus hindfoot in an AAFD. It appears that the correction is not only situated in the calcaneus but also to a lesser extent in the tibia and this resulted in 15% of the achieved HA correction. The novelty is the 3D weightbearing assessment of a hindfoot correction and the shown influence on the tibia. This information could be of use to take in to account when performing a pre-operative planning of a hindfoot deformity.
A Comparative Analysis of Risk and Cost-effectiveness of Outpatient versus Inpatient Hindfoot Fusion
Authors: Moon Andrew , McGee Andrew , Patel Harshadkumar , Huntley Samuel , Pinto Martim , Naranje Sameer , Stibolt Robert , Lehtonen Eva , Pitts Charles , Shah Ashish 
Published: September 2018

Category: Hindfoot Introduction/Purpose: Hindfoot fusion procedures are increasingly being performed in the outpatient setting. However, the cost-effectiveness of hindfoot fusion procedures compared with risk and benefit have not been clearly investigated. The primary objective of this study was to investigate the cost-effectiveness of outpatient versus inpatient hindfoot arthrodesis. Secondary objectives were to compare patient characteristics and short-term complications of patients in each cohort. Methods: This was a retrospective review of all patients who underwent inpatient and outpatient hindfoot fusion procedures at a single institution from 2013-2017. Data collected for each patient included demographic information, operative variables, comorbidities, complications, and any subsequent emergency department visits, readmissions or reoperations. Cost data was collected for each inpatient or outpatient encounter, as well as any subsequent encounters related to the index procedure. Results: Of 151 total hindfoot procedures performed over the study period, 37 were inpatient and 114 were performed in the outpatient setting. There were 3 more readmissions, 22 more ED visits, and 0 more reoperations after outpatient surgery vs inpatient surgery. The average total cost for an outpatient hindfoot fusion procedure was significantly lower than the average total cost for inpatient hindfoot fusion, without a significant increase in complication rate. We are currently in the process of performing the total cost analysis, and will have the completed cost and risk/benefit information within the next two weeks. Conclusion: Outpatient hindfoot fusion surgery may be more cost-effective when compared to inpatient fusion surgery without a significant increase in complications, ED visits, or readmissions.
Last Resort Salvage of Failed Below Knee Amputations
Authors: Strauss Michael 
Published: September 2018

Category: Other Introduction/Purpose: The consequences of failed transtibial amputations especially if the remaining tibia is less than 5 cm is revision to an above knee amputation (AKA). This has important ramifications regarding mobility, energy requirements for ambulation and function. An innovative management protocol has been employed to maximize the likelihood of healing and maintaining a functional knee joint. Methods: Five severely vasculopathic patients with failed short transtibial (TT) amputations and greater than 60 degree knee flexion contractures were followed progressively using the protocol of resecting the remaining fibula, releasing the hamstring insertions, debridement of bursa & cicatrix, osteotomy & beveling of the distal end of the tibia, creative flap closures, and maintenance of knee extension with pins or external fixation across the knee joint. The patient’s courses were followed prospectively. All patients were referred for more proximal amputations, but wanted everything possible be done to salvage their knee joints and avoid AKAs. Four of the five patients were diabetic; one was a smoker with osteomyelitis at the end of the tibia. Results: Salvage of the knee joint occurred in 4 of 5 patients (80%) even though the remaining tibia lengths were 5 cm or less. Threaded 3/16th inch Steinmann pins placed cross-wise through the knee joints were used in 4 patients and an external fixator in a 5th patient. The pins remained for 3 to 6 weeks. Four of the 5 patients achieved healing with 2 of the 4 having initial minor wound dehiscences. The failed case occurred in a diabetic patient with renal failure and only collateral circulation below the groin. There was insufficient viable muscle/fascia in this patient to cover the tibia. The 4 patients who avoided an AKA were able to be fitted with TT prostheses and use them in a functional capacity. Conclusion: The use of temporary pin fixation across the knee joint and removal of the remaining fibula to salvage “end stage” failed TT amputations served the purposes of maintaining knee extension during the healing period, allowing closure & healing of threatened and/or dehisced flaps and maintaining knee function. Motivated, compliant patients with failed, otherwise considered non salvageable TT amputations should be considered for using our protocol in deference to proceeding to an AKA.
Arthroscopic anatomical reconstruction of anterior talofibular ligament and calcaneofibular ligament for chronic ankle instability
Authors: Zhou Yunfeng , Song Bin 
Published: September 2018

Category: Arthroscopy Introduction/Purpose: To evaluate the clinical results of an anatomical reconstruction of anterior talofibular ligament and calcaneofibular ligament under arthroscopy in treatment of chronic ankle instability. Methods From June 2013 to August 2016, 27 patients (28 ankles) with chronic ankle instability were treated with the anatomical reconstruction of anterior talofibular ligaments and calcaneofibular ligaments. All patients were evaluated preoperatively and at the last follow up using the visual analog scale(VAS) score, American Orthopaedic Foot and Ankle Society (AOFAS) score. The talar tilt angle and anterior translation were assessed radiographically in pre- and postoperative ankle stress views. Methods: From June 2013 to August 2016, 27 patients (28 ankles) with chronic ankle instability were treated with the anatomical reconstruction of anterior talofibular ligaments and calcaneofibular ligaments. All patients were evaluated preoperatively and at the last follow up using the visual analog scale(VAS) score, American Orthopaedic Foot and Ankle Society (AOFAS) score. The talar tilt angle and anterior translation were assessed radiographically in pre- and postoperative ankle stress views. Results: The operations were lasted for 75.8 minutes(72~104 minutes). 28 cases were received a mean follow up of 14.8 months(range, 12~25 months. The mean VAS pain score decreased from 5.79 to 1.54(t=26.63, P<0.01), and the medial AOFAS score improved from 63.64 to 90.21(t=-16.57, P<0.01). Imageological examination were completed 16.8 months after the operation (range, 12~25 months). The mean talar tilt decreased from 15.6°to 6.01°(t=25.39, P<0.01),and anterior translation of the talar reduced from a mean of 10.82 to 4.03 mm(t=15.79, P<0.01). Conclusion: Arthroscopic anatomical reconstruction of anterior talofibular ligament and calcaneofibular ligament could improve the function and stability of ankle joints effectively, providing a valid option for treating chronic ankle instability.
Access to primaquine in the last mile: challenges at the service delivery points in pre-elimination era, Myanmar
Authors: Han Kay Thwe , Wai Khin Thet , Oo Tin , Thi Aung , Han Zayar , Aye Daw Kyin Hla , Win Aung Ye Naung , Sattabongkot Jetsumon 
Published: September 2018

Abstract
Background
Alongside monitoring of the disease burden, the successful move towards malaria elimination relies on the readiness of the health care delivery system. However, there is a lack of evidence in the gap of existing National Guidelines and access to low dose primaquine in real practice under varying degrees of antimalarial resistance in the pre-elimination phase in Myanmar. Therefore, this study addressed the essential information from the service delivery points (SDPs) of public and private sectors on the availability and the use of primaquine in both supply and demand side. Concomitantly, the study aimed to underscore challenges in health system infrastructure to promote the sustained flow in rolling out primaquine in line with National Guidelines for malaria elimination.

Methods
A cross-sectional study conducted from September 2017 to February 2018 included six townships of three states/regions. The team used an observation checklist for documenting primaquine supplies at SDPs. Semi-structured interviews, key informant, and in-depth interviews focused both public and private sectors including staff from the Vector-Borne Diseases Control (VBDC) teams in each state/region and rural health centers (n = 25), those from the non-governmental organizations (NGOs), general practitioners and drug sellers (n = 11), and recently infected malaria patients (n = 11). Triangulation of quantitative and qualitative data provided meaningful interpretations.

Results
Public sector staff reported an adequate stock of primaquine, but it was unavailable at the general practitioners’ clinics without any connection to NGOs and also at the unlicensed drug shops. Health care providers of the public sector experienced challenges in poor compliance of malaria patients to primaquine treatment in conjunction with an artemisinin-based combination therapy, loss-to-follow-ups especially in conflict areas, and delays in timely substitution of new batches of primaquine. Respondents from the private sector demanded for the refresher training course on updated antimalarial treatment guidelines.

Conclusion
Monitoring compliance and safety of primaquine treatment was found as a barrier especially among mobile migrant workers and those who were in conflict areas. An alternative strategy by the NMCP could enable to prevent the underutilization of primaquine in vivax malaria to reach the malaria elimination targets.
Migrant Steps: Interview with Göze Saner
Authors: Saner Göze , Yeni Naz 
Published: September 2018

Abstract
Migrant Steps is a theatre project that engages migrant women living in the UK and Europe. Starting from the figure of a travelling tortoise and combining methodologies such as psycho-geography, performance art, physical theatre and autobiographical writing, the project explores the participants’ relationship with the cities where they live.
Book Reviews
Authors: Reid-Walsh Jacqueline , Ue Tom , Wilson Michael , Levy Michael 
Published: September 2018

Abstract
When We Were Alone, David A. Robertson and Julie Flett
(2016) Winnipeg, Manitoba: Highwater Press, 24 pp., ISBN: 978-1-55379-673-2, h/bk, £14.25.
Frankenstein or, The Modern Prometheus: The 200th Anniversary Edition, Mary Shelley (author) and David Plunkert (illus.) (2018) Beverly: Rockport Publishers-The Quarto Group, 248 pp., ISBN 978-1-63159-397-0, h/bk, $25.00
Party Pieces: Oral Storytelling and Social Performance in Joyce and Beckett, Alan W. Friedman (2007) New York: Syracuse University Press, 256 pp., ISBN 978-0-81563-123-1, h/bk, £43.95
Journeys from the Abyss: The Holocaust and Forced Migration from the 1880s to the Present, Tony Kushner (2016) Liverpool: Liverpool University Press, 360 pp., ISBN: 978-1-78694-062-9, h/bk, £85.00, p/bk, £24.95, ebook £24.95
PENGEMBANGAN POTENSI PERTANIAN PERKOTAAN DI KAWASAN SUNGAI PALU
Authors: Hamzens Wildani Pingkan S. , Moestopo Meidy Widayanto 
Published: September 2018

Ide Pengembangan Pertanian Perkotaan di Kawasan Sungai Palu berasal dari peneliti. Ketertarikan meneliti berawal dari adanya keinginan Pemerintah Kota Palu untuk mengembangkan Kota Palu menjadi Kota Hijau. Selain itu, kehadiran Kawasan Ekonomi Khusus di Kota Palu kelak akan menyebabkan peningkatan jumlah penduduk, merupakan peluang menghasilkan bahan pangan. Kawasan Sungai Palu merupakan salah satu lokasi potensial untuk Pengembangan Pertanian Perkotaan, namun Kawasan Sungai Palu perlu ditangani khusus, di sinilah penelitian ini menjadi menarik. Tujuan penelitian untuk mengidentifikasi upaya-upaya yang perlu dilakukan untuk Pengembangan Potensi Pertanian Perkotaan. Penelitian ini termasuk penelitian survei, dan fenomena yang berlangsung adalah data utama yang diolah pada penelitian ini. Teknik analisis data yang digunakan adalah analisis deskriptif berdasarkan hasil observasi. Hasil Penelitian memperlihatkan upaya-upaya yang perlu dilakukan meliputi: (1) Konsolidasi Tanah; (2) Penetapan Jenis Aktivitas ; (3) Perekrutan Pelaksana dan Pembinaan Sumber Daya Manusia ; (4) Penyiapan Prasarana dan Sarana ; dan (5) Manajemen Berkelanjutan.
Algorithms for mapping kidney tissue oxygenation during normothermic machine perfusion using hyperspectral imaging
Authors: Markgraf Wenke , Feistel Philipp , Thiele Christine , Malberg Hagen 
Published: September 2018

AbstractThe lack of donor grafts is a severe problem in transplantation medicine. Hence, the improved preservation of existing and the usage of organs that were deemed untransplantable is as urgent as ever. The development of novel preservation techniques has come into focus. A promising alternative to traditional cold storage is normothermic machine perfusion (NMP), which provides the benefit of improving the organs’ viability and of assessing the organs’ status under physiological conditions. For this purpose, methods for evaluating organ parameters have yet to be developed. In a previous study, we determined the tissue oxygen saturation (StO2) of kidneys during NMP with hyperspectral imaging (HSI) based on a discrete wavelength (DW) algorithm. The aim of the current study was to identify a more accurate algorithm for StO2calculation. A literature search revealed three candidates to test: a DW algorithm and two full spectral algorithms – area under a curve and partial least square regression (PLSR). After obtaining suitable calibration data to train each algorithm, they were evaluated during NMP. The wavelength range from 590 to 800 nm was found to be appropriate for analyzing StO2of kidneys during NMP. The PLSR method shows good results in analyzing the tissues’ oxygen status in perfusion experiments.
Awheel Along Europe’s Rivers: Geoarchaeological Trails for Cycling Geotourists
Authors: Hose Thomas A. 
Published: September 2018

AbstractThis review study presents an overview of the potential for the development of geoarchaeological trails for leisure cyclists in Europe. It initially defines and discusses the underpinning key concepts and then examines the nature and main needs of leisure cyclists. It considers and recognises appropriate geo-interpretative themes, of geological/geomorphological and archaeological/historical interest, to employ in developing the trails. Noting that river valleys have long been natural route-ways for human expansion into Europe (as exemplified by the ‘Stone Age’ and the Roman Empire), and that many of today’s major cycle trails are beside rivers with loess deposits, a geoarchaeological geotourism strategy is considered in relation to them. Case studies of specific sites, from central southern England, the Middle Danube and Middle Rhine valleys, outline the current provision and the basis of the proposed trails. Finally, a common relatively low-cost, mixed media, geo-interpretative and promotional approach could generate the impetus to further develop the strategy is suggested.
Copper-catalyzed synthesis of 2,3-disubstituted quinazolin-4(3H)-ones from benzyl-substituted anthranilamides
Authors: Foroumadi Parham , Lotfi Vahid , Mahdavi Mohammad , Moghimi Setareh , Soheilizad Mehdi , Kianmehr Ebrahim , Firoozpour Loghman , Asadipour Ali , Foroumadi Alireza 
Published: September 2018

Abstract
An efficient, practical approach to the copper-catalyzed synthesis of 2,3-disubstituted quinazolin-4(3H)-one derivatives is described. The preparation involves treatment of benzyl amines with benzyl anthranilamides in the presence of Cu(OAc)2 and tetra-n-butylammonium bromide (TBAB).
The influence of thyroid disorders on bone density and biochemical markers of bone metabolism
Authors: Tsevis Konstantinos , Trakakis Eftihios , Pergialiotis Vasilios , Alhazidou Eleni , Peppa Melpomeni , Chrelias Charalampos , Papantoniou Nikolaos , Panagopoulos Periklis 
Published: September 2018

Abstract

Background
Thyroid dysfunction, predominantly hyperthyroidism, has been previously linked to impaired bone mass density (BMD) and increased risk of fractures. On the other hand, data in the field of hypothyroidism (HT) are missing. The purpose of the present study was to investigate the impact of thyroid disorders on bone density serum and urine calcium (Ca) and phosphate (P) as well as serum osteocalcin and alkaline phosphatase and urine hydroxyproline in a series of post-menopausal women.

Materials and methods
The study was conducted in the Reproductive Endocrinology Outpatient Clinic of our hospital. A consecutive series of post-menopausal women was included, after excluding patients under hormone treatment (including levothyroxine supplementation) and those who received raloxifene, tamoxifen or tibolone during the study period as well as those who received treatment during the previous 12 months were excluded from the present study.

Results
Overall, 188 women were included in the present study. Among them, 143 women had normal thyroid function, 32 women had hyperthyroidism and 13 women had HT. Correlation of thyroid function indices with osteoporosis indices revealed statistically significant correlations between thyroxine (T4) and free triiodothyronine (T3) with T-, Z-scores and BMD. Logistic regression analysis concerning the impact of HT and hyperthyroidism on T-score, Z-score and bone mass density revealed that both pathological entities negatively affect bone health (p < 0.05).

Conclusion
The findings of our study suggest that not only hyperthyroidism, but also HT negatively affects BMD. Future studies should investigate this association and corroborate our findings.
Effect of machine scatter on the rotating bending fatigue life of materials
Authors: Banavasi Shashidhar M. , Ravishankar K.S. , Naik Padmayya S. 
Published: September 2018

AbstractRotating bending fatigue test results vary from specimen to specimen even if materials are tested in a standard laboratory set up because rotating bending fatigue life or fatigue strength depends upon various factors due to its dynamic action. One method of testing may be machine scatter (offset and angular misalignment). Angular misalignments are unavoidable in dynamic machines due to continuous operation leading to transverse vibrations in specimens. The magnitude of transverse vibrations was measured manually by dial gauge arrangement. Experiments were carried out until fracture either with smooth running conditions or with the effects of offset and angular misalignment. The enhanced effect of misalignments on fatigue life was done through the histogram normal distribution technique. There was a clear distinction between the appearances of the fracture surfaces between the specimens subjected to smooth running conditions and specimen vibration, which reveals general fatigue fracture phenomena and intergranular fatigue cracks, larger decohesion of graphite nodules and isolated cleavage facets. The manual technique used without any resistance strain gauges, as they were not efficiently sustainable under repetitive loads, helped in understanding the dynamic machine scatter on fatigue life in an economical way where there were lesser concentrations in these areas.
Effect of dual tocolysis with fenoterol and atosiban in human myometrium
Authors: Stoiber Bernhard , Haslinger Christian , Schäffer Marie Kristin , Zimmermann Roland , Schäffer Leonhard 
Published: September 2018

AbstractObjectivesTo measure the tocolytic effect of the combination of the oxytocin receptor antagonist atosiban with the β-mimetic agent fenoterol on human myometrium of pregnant women.MethodsAnin vitrostudy of contractility in human myometrium at the Laboratory of the Department of Obstetrics, University Hospital of Zürich, Switzerland, was performed. Thirty-six human myometrial biopsies were obtained during elective caesarean sections of singleton pregnancies at term. Tissue samples were exposed to atosiban, fenoterol and the combination of atosiban with fenoterol. Contractility was measured as area under the curve during 30 min of spontaneous contractions. The effect of treatment was expressed as the percentage of change from basal activity during 30 min of exposure. Differences were calculated using a paired Wilcoxon signed-rank test. An additive effect of dual tocolysis was assumed when no significant difference was detected between the observed and expected inhibition of dual tocolysis. When inhibition was greater or lower than expected, the dual combination was characterised as “synergistic” or “antagonistic”, respectively.ResultsAtosiban and fenoterol alone suppressed contractions by a median of 43.2% and 29.8%, respectively. The combination of atosiban plus fenoterol was measured at a level of 67.3% inhibition. There was no significant difference in the expected (63.2%) and observed inhibition effect of dual tocolysis (P=0.945).ConclusionThis study demonstrated an additive effect of dual tocolysis of atosiban and fenoterol on human myometriumin vitro, but no synergistic or antagonistic effect.