bluuebunny/crossref_metadata_2025_split huggingface dataset:
Longterm renal outcome of biopsy-proven acute tubular necrosis and acute interstitial nephritis
Authors: Kim Hyunseo , Kyung Sang , Ahn Shin Young , Kwon Young Joo , Lee Hajeong , Oh Jieun , Chin Ho Jun , Lim Ki Joon , Lee Jun Yong , Yang Ji Hyun , Kim Myung-Gyu , Cho Won Yong , Oh Sewon 
Published: September 2019

Abstract
Background: Although emerging evidence suggest acute kidney injury (AKI) progress to chronic kidney disease (CKD), longterm renal outcome of AKI still remains unclear. Unlike glomerular diseases, AKI is usually diagnosed in the clinical context without kidney biopsies, and lack of histology might contribute to this uncertainty. Acute tubular necrosis (ATN) is the most common cause of AKI due to ischemia, toxin or sepsis. Acute interstitial nephritis (AIN), caused by drugs or autoimmune diseases is also increasingly recognized as an important cause of AKI. Methods: Among 8,769 biopsy series, 253 adults who were histologically diagnosed with ATN and AIN from 1982 to 2018 at five university hospitals were included. Demographic and pathological features that are associated with the development of end stage renal disease (ESRD) were also examined. Results: Rate of non-recovery of renal function at 6 month was significantly higher in the AIN (ATN vs AIN 49.3 vs 69.4%, p=0.007) with a 2.709-fold higher risk of non- recovery compared to ATN (95% CI: 1.203–6.470). During the mean follow up of 76.5±91.9 months, ESRD developed in 39.4% of patients with AIN, and 21.5% patients of ATN. The risk of ESRD was significantly higher in AIN (23.050; 95% CI: 2.420-219.533) and also in ATN (12.136; 95% CI, 1.186-24.235) compared to control with non-specific pathology. Older age, female gender, renal function at the time of biopsy and at 6 months, proteinuria and pathological features including interstitial inflammation and fibrosis, tubulitis, vascular lesion were significantly associated with progression to ESRD. Conclusions: Our study demonstrated that patients with biopsy proven ATN and AIN are at high risk of developing ESRD.
A multi-methodological study of kurnakovite: A potential B-rich aggregate
Authors: Gatta G. Diego , Guastoni Alessandro , Lotti Paolo , Guastella Giorgio , Fabelo Oscar , Fernandez-Diaz Maria Teresa 
Published: September 2019

AbstractThe crystal structure and crystal chemistry of kurnakovite from Kramer Deposit (Kern County, California), ideally MgB3O3(OH)5·5H2O, were investigated by single-crystal neutron diffraction (data collected at 293 and 20 K) and by a series of analytical techniques aimed to determine its chemical composition. The concentration of more than 50 elements was measured. The empirical formula of the sample used in this study is Mg0.99(Si0.01B3.00)Σ3.01O3.00(OH)5·4.98H2O. The fraction of rare earth elements (REE) and other minor elements are, overall, insignificant. Even the content of fluorine, as a potential OH-group substituent, is insignificant (i.e., ~0.008 wt%). The neutron structure model obtained in this study, based on intensity data collected at 293 and 20 K, shows that the structure of kurnakovite contains: [BO2(OH)]-groups in planar-triangular coordination (with the B-ions in sp2 electronic configuration), [BO2(OH)2]-groups in tetrahedral coordination (with the B-ions in sp3 electronic configuration), and Mg(OH)2(H2O)4-octahedra, connected into (neutral) Mg(H2O)4B3O3(OH)5 units forming infinite chains running along [001]. Chains are mutually connected to give the tri-dimensional structure only via hydrogen bonding, and extra-chains “zeolitic” H2O molecules are also involved as “bridging molecules.” All the oxygen sites in the structure of kurnakovite are involved in hydrogen bonding, as donors or as acceptors.The principal implications of these results are: (1) kurnakovite does not act as a geochemical trap of industrially relevant elements (e.g., Li, Be, or REE), (2) the almost ideal composition makes kurnakovite a potentially good B-rich aggregate in concretes (for example, used for the production of radiation-shielding materials for the elevated ability of 10B to absorb thermal neutrons), which avoids the risk to release undesirable elements, for example sodium, that could promote deleterious reactions for the durability of cements.
Diabetes-induced Proteome Changes Throughout Development
Authors: Johar Dina , Ahmed Sara M. , El. Hayek Samer , Al-Dewik Nader , Bahbah Eshak I. , Omar Nabil H. , Mustafa Mahmoud , Salman Doaa O. , Fahmey Asmaa , Mottawea Mohamed , Azouz Rasha A.M. , Bernstein Larry 
Published: September 2019

Background:Diabetes Mellitus (DM) is a multisystemic disease involving the homeostasis of insulin secretion by the pancreatic islet beta cells (β-cells). It is associated with hypertension, renal disease, and arterial and arteriolar vascular diseases.Discussion:The classification of diabetes is identified as type 1 (gene linked β-cell destruction in childhood) and type 2 (late onset associated with β-cell overload and insulin resistance in peripheral tissues. Type 1 diabetes is characterized by insulin deficiency, type 2 diabetes by both insulin deficiency and insulin resistance. The former is a genetically programmed loss of insulin secretion whereas the latter constitutes a disruption of the homeostatic relationship between the opposing activity of β- cell insulin and alpha cell (α-cell) glucagon of the Islets of Langerhans. The condition could also occur in pregnancy, as a prenatal occurring event, possibly triggered by the hormonal changes of pregnancy combined with β-cell overload. This review discusses the molecular basis of the biomolecular changes that occur with respect to glucose homeostasis and related diseases in DM. The underlying link between pancreatic, renal, and microvascular diseases in DM is based on oxidative stress and the Unfolded Protein Response (UPR).Conclusion:Studying proteome changes in diabetes can deepen our understanding of the biomolecular basis of disease and help us acquire more efficient therapies.
Upaya Meningkatkan Aktivitas dan Prestasi Belajar Siswa Pada Bidang Studi Biologi Melalui Penerapan Metode Pembelajaran Kooperatif Tipe STAD
Authors: Sulastiyo Sulastiyo 
Published: September 2019

Penelitian tindakan ini dilatarbelakangi oleh permasalahan yang timbul dalam pembelajaran Biologi, khususnya pada materi atau kompetensi dasar ”Mendeskripsikan ciri-ciri virus, replikasi dan peranannya dalam kehidupan” di kelas X-1 Semester I SMA Negeri 2 Muara Bungo. Guru dengan berbagai cara telah mengusahakan agar semua siswa aktif dalam kegiatan pembelajaran. Pembelajaran standar juga telah dilaksanakan, berbagai media pembelajaran yang ada di sekolah telah dimanfaatkan, berbagai bentuk penugasan telah pula diberikan untuk dilaksanakan oleh siswa, baik di dalam maupun di luar kelas, mulai dari tugas melakukan observasi, melakukan eksperimen, membuat laporan singkat hasil eksperimen atau hasil observasi, mengerjakan LKS, dan lain sebagainya. Namun demikian, dalam berbagai kesempatan tanya jawab, diskusi kelas, maupun ulangan harian, aktivitas dan prestasi belajar mereka sangat rendah. Berdasarkan catatan guru, aktivitas siswa dalam tanya jawab dan diskusi kelas masing-masing hanya sebesar 30% dan 35% dari 40 siswa yang ada. Sebagian besar dari siswa justru memperlihatkan aktivitas yang tidak relevan dengan pembelajaran, seperti kelihatan bengong dan melamun, kurang bergairah, kurang memperhatikan, bermain-main sendiri, berbicara dengan teman ketika dijelaskan, canggung berbicara atau berdialog dengan teman waktu diskusi, dan lain sebagainya. Sementara itu dari hasil ulangan harian/ulangan blok, prestasi belajar mereka hanya sebesar 45% yang berhasil mencapai batas KKM (Kriteria Ketuntasan Minimal).
Kata Kunci:Model STAD, Biologi, SMA N 2 Muara Bungo
Gestalt Counseling with Dialog Game Techniques and Hipno Counseling Techniques for Self Achievement
Authors: Paramartha Wayan Eka , Dharsana I Ketut , Suarni Ni Ketut 
Published: September 2019

The purpose of this research is to know the influence between gestalt counseling with techniques of game dialogue and hipnocounseling technique against self achievement in terms of the gender of the student. The research is the research experiments with 2 x 2 factorial design, this research was conducted in SMA Negeri 1 Sukasada. The Sampling technique used to determine the research sample is Random sampling. Data collection methods used are observation, interview, questionnaire and diary, recording documents. Data research results are analyzed using two lines of Anova. The results showed that, there may be differences between the influence of gestalt counseling with techniques of game dialogue and hipnocounseling technique against self achievement.
PENERAPAN MODEL PEMBELAJARAN MAKE A MATCH UNTUK MENINGKATKAN PERKEMBANGAN KOGNITIF DALAM MENGENAL LAMBANG BILANGAN
Authors: Desy Pratiwi Handaryani Ni Md , Pudjawan I Ketut 
Published: September 2019

This research is a classroom action research which aims to determine the improvement of cognitive development in recognizing the number symbol after applying the make a match learning model to the children of A1 TK Kartika VII-3 Singaraja group. This research is classroom action research (CAR) which is carried out in two action cycles. The subjects of this study were students of A1 group TK Kartika VII-3 Singaraja in 2018/2019 Academic Year which consisted of 18 students, consisting of 8 girls and 10 boys. The analytical method used is descriptive statistical analysis method and quantitative descriptive analysis method. The results of data analysis in this study indicate that there is an increase in the average percentage of cognitive development in recognizing the symbol of numbers in children in group A1 of 15.25%. This can be seen from the increase in the average percentage of cognitive development in recognizing the symbol of child numbers in the first cycle of 65.25% with the criteria being medium to 80.50% in cycle II with high criteria. Thus, it can be concluded that the application of the make a match learning model can improve cognitive development in recognizing the symbolic number of children in Group A1 TK Kartika VII-3 Singaraja Academic Year 2018/2019 Keywords: Make a match, Cognitive Development, Number Symbols
PENERAPAN MODEL PEMBELAJARAN TALKING STICKBERBANTUAN MEDIA FLASH CARD UNTUK MENINGKATKANKEMAMPUAN BERBICARA PADA ANAK
Authors: Sugiantiningsih Ida Ayu , Aditya Antara Putu 
Published: September 2019

This study aims to determine the improvement of speaking ability after the application of talking stick learning model assisted with flash card as media to improve the ability to speak to the group of children of B2 TK Kartika VII-3 Singaraja in 2018/2019 academic year. This research is a Class Action Research (CAR) which has been carried out with 2 research cycles. The subject of the study was the group of children of the TK Kartika VII-3 Singaraja B2, amounting to 18 children, consisting of 10 boys and 8 girls. The data collection methods used in this study were photos and videos observation and documentation methods. The data from research results were analyzed using descriptive statistical analysis methods and quantitative descriptive analysis methods. The results of data analysis showed that there was an enhancement of speaking ability after the implementation of cooperative learning model talking stick assisted by flash card, this can be seen from the enhancement in the average of percentage in the first cycle of 67.08% with the criteria being increased in the second cycle to 81.91% who are in high criteria. Therefore an increase in the average number of percentages from cycle I to cycle II is 14.83%. It can be concluded that the application of talking stick learning model assisted by flash card media can improve the ability to speak to the group of children of B2 TK Kartika VII-3 Singaraja in 2018/2019 academic year. Key words: talking stick learning model, flash card, speaking ability
Pengaruh Model Pembelajaran Circuit Learning Berbantuan Media Flip Chart terhadap Hasil Belajar IPA
Authors: Pramita Pt. Ayu , Sudarma I Km. , Murda I Nym. 
Published: September 2019

Permasalahan rendahnya hasil belajar IPA siswa kelas V SD di Gugus III Kecamatan Seririt menjadi masalah utama dilakukannya penelitian ini. Rendahnya hasil belajar IPA terjadi karena pembelajaran masih berpusat pada guru dan siswa cenderung pasif. Oleh karena itu, penelitian ini dilakukan dengan tujuan untuk mengetahui perbedaan hasil belajar IPA antara kelompok siswa yang dibelajarkan dengan model pembelajaran Circuit Learning berbantuan media flip chart dan kelompok siswa yang dibelajarkan dengan pembelajaran konvensional pada siswa kelas V semester II SD di Gugus III Kecamatan Seririt. Penelitian ini merupakan penelitian eksperimen semu dengan rancangan Nonequivalent Posttest-Only Control Group Design. Populasi penelitian adalah seluruh kelas V semester II di SD Gugus III Kecamatan Seririt tahun pelajaran 2017/2018 yang berjumlah 143 siswa. Sampel diambil dengan teknik random sampling. Sampel penelitian yaitu kelas V SD Negeri 2 Seririt sebagai kelas eksperimen yang berjumlah 22 siswa dan kelas VA SD Negeri 3 Seririt sebagai kelas kontrol yang berjumlah 25 siswa. Metode pengumpupulan data yang digunakan adalah metode tes. Data yang dikumpulkan dianalisis menggunakan analisis statistik deskriptif dan statistik inferensial. Hasil penelitian menunjukkan bahwa terdapat perbedaan hasil belajar IPA antara kelompok siswa yang dibelajarkan dengan model pembelajaran Circuit Learning berbantuan media flip chart dan kelompok siswa yang dibelajarkan dengan pembelajaran konvensional dengan thitung = 7,844 lebih besar ttabel = 2,014 denga taraf signifikansi 5%. Berdasarkan hal tersebut, dapat disimpulkan bahwa model pembelajaran Circuit Learning berbantuan media flip chart berpengaruh terhadap hasil belajar IPA siswa Kata kunci: Circuit Learning, Flip Chart, Hasil Belajar IPA.
PERBEDAAN MODEL PROBEM BASED LEARNING DAN DISCOVERY LEARNING TERHADAP HASIL BELAJAR MATEMATIKA
Authors: Rahmawati Dewi 
Published: September 2019

AbstrakPenelitian ini bertujuan untuk mengetahui perbedaan yang signifikan hasil belajar Matematika antara siswa yang menggunakan model pembelajaran Problem Based Learning dengan Discovery Learning pada siswa kelas 4 SD Gugus Kanigoro Kecamatan Tingkir dan Gugus Imam Bonjol Kota Salatiga Tahun Pelajaran 2017/2018.Jenis penelitian ini adalah penelitian eksperimen semu. Desain penelitian ini yaitu Nonequivalent Control Group Design.Populasi penelitian ini adalah seluruh siswa kelas 4 SD Gugus Kanigoro sejumlah 125 siswadan Gugus Imam Bonjol yang berjumlah 117 siswa. Sampel penelitian ini yaitu kelas 4 SDN Sidorejo Kidul 02 yang berjumlah 28 orang dan siswa kelas 4 SDN Sidorejo Lor 04 yang berjumlah 40 orang. Metode pengumpulan data dilakukan dengan metode tes yaitu dengan instrumen tes objektif (pilihan ganda). Data yang diperoleh dianalisis dengan menggunakan teknik analisis statistik deskriptif dan teknik analisis statistik inferensial yaitu uji-t. Hal ini dapat dilihat dari skor rata-rata siswa yang menggunakan model pembelajaran Discovery learning yaitu 70,93 dan skor rata-rata siswa yang menggunakan model pembelajaran Problem Based learning yaitu 73,87. . Berdasarkan hasil uji T-Test dapat dilihat bahwa nilai asyimp. Sig (2-tailed) sebesar 0.016 lebih kecil dari nilai α =0.05 sehingga terima 𝐻0 dan tolak 𝐻1. Hasil uji tersebut memberikan kesimpulan terdapat perbedaan hasil belajar matematika yang signifikan pada siswa kelas 4 SD Gugus Kanigoro dan Gugus Imam Bonjol dalam pembelajaran menggunakan model pembelajaran Problem based Learning dan Discovery Learning. Kata Kunci : Pembelajaran Matematika, Model Problem based Learning, Model Discovery Learning
PENGARUH MODEL PEMBELAJARAN INQUIRY BERBANTUAN MEDIA ANIMASI TERHADAP KOMPETENSI PENGETAHUAN IPA
Authors: Dewi Ayu Cintya 
Published: September 2019

This study aimed at determining the significant effect of science knowledge competence between groups of students who are taught by using inquary learning model which assisted by animated media with groups of students who are taught through conventional learning in fourth grade students of SD Gugus Dewi Sartika academic year 2017/2018. This study was a quasi experimental research with non-equivalent control group design. The population of this study was all fourth grade students of SD Gugus Dewi Sartika which amounted to 266 students. The sample was determined by random sampling technique so that there would be fourth grade of SD Negeri 3 Pedungan as experiment group which amounted to 45 people and fouth grade B of SD Negeri 13 Pedungan as control group which amounted to 30 people. The data collection in this research was done by the test method and the instrument used in the form of ordinary double choice objective test. Data of knowledge competence was analyzed by t-test polled variance. The analysis result indicated that there was a significant effect of science knowledge competence between group of students which was taught by using inquary learning model which assisted by animated media with group of students that was taught by using conventional learning in fourth grade students of SD Gugus Dewi Sartika academic year 2017/2018. Thus, it can be concluded that Inquiry Learning Model which assisted by animated media have a significant effect on science knowledge competence of fourth grade students of SD Gugus Dewi Sartika academic year 2017/2018, and the Inquiry Learning Model which assisted by animated media can be used in studying science so as to create the kind of learning. Keywords : Inquiry, Animation , Science Knowledge Competence
PENGARUH PENDEKATAN CONTEXTUAL TEACHING AND LEARNING BERBASIS PENILAIAN PORTOFOLIO TERHADAP KOMPETENSI PENGETAHUAN IPA
Authors: Dewi Dw Ayu Prami Handayani 
Published: September 2019

This research has an aim to determine the impact of CTL approach based on the portfolio assessment on science knowledge competence of grade V students Gugus I Gusti Ngurah Rai Denpasar Selatan of the academic year 2017/2018. This type of research is an experiment using Non-equivalent control group design research plan. The population of this research is all grade V students Gugus I Gusti Ngurah Rai with the total number of 263 students. The determination of the sample in this research is using random sampling technique with random class. The sample of the research is the student of grade Vc SDN 4 Sanur with the total amount 35 students as an experiment group and the grade V student SDN 8 Sanur with the total of 41 students as a control group. The competence data of science knowledge competence was collected by instruments in the form of multiple choice objective tests with 32 test items that has been validated. The data obtained were analyzed using statistic-descriptive method and statistic-inferential method, afterwards hypothesis test using (t) test. The result of the analysis data obtained thitung = 5,955 meanwhile, at the level of significance 5% and dk = 74 obtained score ttabel = 2,000 therefore, thitung = 5,955 > ttabel = 2,000. The average of science knowledge competence of an experiment group student = 78,00 > = 67,28 control group. Therefore, It can be concluded that the CTL approach based on the portfolio assessment has an effect on the science knowledge competence of the students of grade V Gugus I Gusti Ngurah Rai Denpasar Selatan Academic Year 2017/2018. Keywords : CTL, portfolio assessment, science knowledge competence.
HUBUNGAN PENGETAHUAN TENTANG PENDIDIKAN SEKS DENGAN PERILAKU SEKSUAL REMAJA
Authors: Muarifah Afifatul , Danny Soesilo Tritjahjo , Tagela Umbu 
Published: September 2019

Penelitian dilaksanakan di SMK N 1 Pringapus. Subjek dalam penelitian ini adalah kelas X TSM SMK N 1 Pringapus. Teknik analisis data yang digunakan adalah Kendall’s tau. Teknik pengambilan sampel menggunakan teknik total sampling. Pengambilan sampel menggunakan sampel total seluruh siswa kelas XI Tata Busana SMK Negeri 1 Pringapus yang berjumlah 116 siswa. Pengumpulan data menggunakan dua jenis skala, yaitu skala, pengetahuan tentang pendidikan seks dan perilaku seksual yang dikembangkan oleh peneliti berdasarkan teori dari Rahman dan Fachrudin (2000), dan penulis mengadopsi dari Febrian Firza (2011) serta teori Arum dalam Octaviani (2009) dan penulis mengadopsi dari Febrian Firza (2011). Pengolahan datanya menggunakan progam SPSS for Windows 17.0 version. Hasil penelitian menunjukkan bahwa ada hubungan pengetahuan tentang pendidikan seks dengan perilaku seksual remaja siswa kelas XI Tata Busana SMK Negeri 1 Pringapus tahun pelajaran 2018/2019, dengan nilai r = 0,435 dan koefesien signifikansi 0,000 ≤ 0,05. Maka hubungan kedua variabel tersebut positif dan signifikan. Dengan demikian, hipotesis peneliti Ada Hubungan Signifikan Antara Pengetahuan Tentang Pendidikan Seks Dengan Perilaku Seksual Remaja Siswa Kelas XI Tata Busana SMK Negeri 1 Pringapus Tahun Ajaran 2018/2019”, jadi dapat dikatakan hipotesis diterima.Kata kunci: Pengetahun Tentang Pendidikan Seks, Perilaku Seksual
KEEFEKTIFAN MODEL PROBLEM BASED LEARNING (PBL) DENGAN MEDIA DAKOTA TERHADAP HASIL BELAJAR MATERI FPB DAN KPK
Authors: Dwi Ariyanti Mei Riska , . Rasiman , Asri Untari Mei Fita 
Published: September 2019

Peneliti ini bertujuan untuk mengidentifikasi efektif atau tidaknya model pembelajaran Problem Based Learning dengan media DAKOTA terhadap hasil belajar materi FPB dan KPK siswa kelas IV SD Negeri Banyubiru 01 Kabupaten Semarang. Penelitian ini merupakan penelitian ekperimen jenis kuantitatif. Penelitian ini menggunakan One Group Pretest-Posttest Design. Populasi dalam penelitian ini adalah semua peserta didik kelas IV SD Negeri Banyubiru 01 Kabupaten Semarang berjumlah 39 siswa tahun ajaran 2018/2019. Intrumen yang digunakan adalah (1) wawancara untuk mendapatkan informasi tentang kondisi awal siswa serta materi yang akan diajarkan. (2) Dokumentasi mendapatkan dokumen sekolah mengenai nama siswa, jumlah siswa, dan data-data yang diperlukan dalam penelitian daftar nilai, daftar nama siswa dan dokumen pelaksanaan kegiatan pembelajaran selama penelitian. (3) tes untuk mengukur ini untuk mengukur hasil belajar siswa aspek kognitif. Analisis Data menggunakan Teknis analisis data peneliti menggunakan uji normalitas, uji homogenitas dan uji hipotesis (uji-t). Uji normalitas digunakan untuk mengetahui kelas tersebut berdistribusi normal atau tidak. Uji Homogenitas Untuk menguji homogenitas varians dari dua kelompok data Uji hipotesis menggunakan uji t-test. Hasil penelitian yang dilakukan dapat disimpulkan bahwa model pembelajaran Problem Based Learning dengan media DAKOTA efektif terhadap hasil belajar materi FPB dan KPK kelas IV SDN Banyubiru 01 Kabupaten Semarang. Hal ini dapat dilihat dari rata-rata hasil postest lebih tinggi dari pada pretest selain itu diperkuat dengan hasil perhitungan uji t diperoleh thitung untuk hasil belajar sebesar 14,999 dan dan ttabel sebesar 1,684 karena thitung (14,999) > ttabel (1,684) maka hal ini menunjukkan bahwa uji t hasil belajar signifikan.Kata Kunci : Problem Based Learning, DAKOTA, Hasil Belajar, Matematika