bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Test Geometry and Aggregate Texture on Angle of Repose of Aggregates
Authors: Swamy Aravind Krishna , Matolia Varun , Singh Parminder , Ramana Gunturi Venkata 
Published: August 2018

Abstract
Properties of asphalt concrete mixtures are significantly affected by aggregate properties. Previous studies have indicated that Angle of Repose (AoR) is an indicator of aggregate properties, including texture, angularity, and shape. In this research, the effect of test geometry and aggregate texture on the AoR of aggregate is evaluated. Aggregates from two different sources were synthetically processed in a laboratory to obtain particles with different textures while retaining other characteristics. The AoR of single-sized aggregates was measured with different test geometries. The test results indicate that measured AoR was sensitive to aggregate texture and test geometry. The relation between aggregate size and AoR exhibited a positive correlation. The direct shear strength test parameters were able to capture the changes in aggregate texture and AoR. The angle of internal friction showed a positive and linear variation with AoR, irrespective of test geometry. However, exact slope was specific to aggregate type and texture level.
Diagnosis of Photovoltaic (PV) Panel Defects Based on Testing and Evaluation of Thermal Image
Authors: Uma J. , Muniraj C. , Sathya N. 
Published: August 2018

Abstract
Photovoltaic (PV) solar energy can only be economical if the PV module operates reliably for 25–30 years under field conditions. The PV module and it overall reliability can be radically affected by faults during the manufacturing process, in real field conditions, transportation, and installation. So, there is a need for diagnosing defects in PV modules to improve their reliability. Operating temperature plays the key role for improving the efficiency of PV panels. The temperature within the PV cell unevenly increases because of such defects in the cell. As such, it is very important to monitor the temperature and temperature distribution in PV panels in order to locate such defects. Infrared thermography (IRT) plays a major role in predictive and preventive maintenance of PV panels and can determine the severity of the problem. This article investigates the delamination, snail trails, and bubbled faults of PV panels using digital thermal image analysis and their feature extraction. Real time experiments were conducted, and the test results are presented in this article. Thermal images of panels are captured using a (FLIR) T420bx® thermal imager. The thermal images of panels are analyzed by segmenting the image using the k-means clustering algorithm. Histogram statistical features such as mean, standard deviation, variance, entropy, skew, and kurtosis are extracted from the segmented thermal image. Based on these features, the defects in PV panels are identified with reasonable accuracy.
A Note on Determination of the Preconsolidation Pressure
Authors: Soltani Amin , Taheri Abbas , Deng An , Azimi Mahdieh 
Published: August 2018

Abstract
The preconsolidation pressure, σ′y, is commonly interpreted by means of empirical observations (or graphical constructions) with respect to e–logσ′ stress patterns (e = void ratio, and σ′ = effective stress) exhibited in the conventional oedometer test. As with any empirical/graphical procedure, the resulting estimations are associated with subjective variability and thus yield inconsistent results among individuals. Recently, the mathematical translational technique was implemented by the authors, thereby promoting a subjective-free computational framework, denoted as the 3PRH framework, for interpretation of σ′y with respect to four common graphical constructions (i.e., three semi-log and one bi-log construction), covering a variety of geometrical complexity. In this article, the 3PRH framework was first revisited in a more practical sense. The framework was then implemented to a compiled database of 34 consolidation tests to arrive at reliable correlations/comparisons between the four graphical constructions. Finally, the settlement dependency on σ′y (or type of graphical construction) was statistically examined to recommend measures for reliable settlement analyses.
The effect of subacute lead exposure on selected blood inflammatory biomarkers and angiogenetic factors
Authors: Machoń-Grecka Anna , Dobrakowski Michał , Kasperczyk Aleksandra , Birkner Ewa , Pryzwan Tomasz , Kasperczyk Sławomir 
Published: August 2018

Abstract

Objectives
The aim of the study was to examine blood levels of selected pro-inflammatory cytokines, C reactive protein (CRP), and selected factors that influence angiogenesis in workers exposed to lead for a short period of time.

Methods
The study population consisted of 36 male workers (mean age 41 ± 14 years) exposed to lead for 40 days.

Results
The mean blood lead level (BLL) was 10.7 ± 7.67 μg/dl at the beginning of the study, and increased to 49.1 ± 14.1 μg/dl at the end of the study period. The levels of macrophage inflammatory protein 1-α (MIP-1α) were significantly higher after the studied exposure to lead compared to the baseline by 71%. Similarly, the values of CRP increased by 35%. Conversely, the values of soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) and fibroblast growth factor-basic (FGF-basic) decreased by 14% and 21%, respectively. After the examined period of lead exposure, analysis of correlations showed positive correlations between vascular endothelial growth factor (VEGF) levels and the levels of interleukin 1β (IL-1β) (R = 0.39), interleukin 6 (IL-6) (R = 0.42), and MIP-1α (R = 0.54). Positive correlations were identified between MIP-1α and FGF-basic (R = 0.38), soluble angiopoietin receptor (sTie-2) (R = 0.41), and sVEGFR-1 (R = 0.47).

Discussion
Short-term exposure to lead induces the inflammatory response; however, these mechanisms seem to be different from those observed in chronic lead exposure. Subacute exposure to lead may dysregulate angiogenesis via modifications in the levels of angiogenic factors.
The Japanese Workplace PERMA-Profiler: A validation study among Japanese workers
Authors: Watanabe Kazuhiro , Kawakami Norito , Shiotani Toru , Adachi Hidehiko , Matsumoto Kaori , Imamura Kotaro , Matsumoto Kei , Yamagami Fumino , Fusejima Ayumi , Muraoka Tomoko , Kagami Tomomitsu , Shimazu Akihito , Kern Margaret L 
Published: August 2018

Abstract

Objectives
Although well-being at work is important for occupational health, multi-dimensional workplace well-being measures do not exist for Japanese workers. The purpose of this study was to investigate the validity of the Japanese version of the Workplace PERMA-Profiler.

Methods
Japanese workers completed online surveys at baseline (N = 310) and 1 month later (N = 100). The Workplace PERMA-Profiler was translated according to international guidelines. Job and life satisfaction, work engagement, psychological distress, work-related psychosocial factors, and work performance were measured as comparisons for convergent validity. Cronbach’s alphas, Intra-class Correlation Coefficients (ICCs), and measurement errors were calculated for the reliability, and the validity of the measure was tested by correlational analyses and confirmatory factor analysis.

Results
A total of 310 (baseline) and 86 (follow-up) workers responded and were included in the analyses. Cronbach’s alphas and ICCs of the Japanese Workplace PERMA-Profiler ranged from 0.75 to 0.96. Confirmatory factor analysis indicated that the 5-factor model demonstrated a marginally acceptable fit (χ2 (80) = 351.30, CFI = 0.892, TLI = 0.858, RMSEA = 0.105, SRMR = 0.051). Overall well-being and the five PERMA domains had moderate-to-strong correlations with job satisfaction, psychological distress (inversely), and work-related factors.

Conclusions
The Japanese version of the Workplace PERMA-Profiler demonstrated adequate reliability and validity. This measure could be useful to assess well-being at work, promote well-being research among Japanese workers, and address the problem of definition for well-being in further studies.
Day-to-day variations in daily rest periods between working days and recovery from fatigue among information technology workers: One-month observational study using a fatigue app
Authors: Kubo Tomohide , Izawa Shuhei , Tsuchiya Masao , Ikeda Hiroki , Miki Keiichi , Takahashi Masaya 
Published: August 2018

Abstract

Background
The European Union’s Working Time Directive stipulates recovery periods as “Eleven consecutive hour daily rest periods (DRPs) between working days.” In Japan, adopting this regulation has been discussed.

Objective
To examine the association between weekday DRPs and recovery from fatigue by conducting a one-month observational study using a fatigue monitoring application (fatigue app) on a smart tablet.

Methods
Fifty-five daytime employees working at an information technology company participated in this study. Visual analogue scales (VAS) regarding fatigue, psychological detachment from work, a psychomotor vigilance task (PVT), and sleep-wake logs were repeatedly measured using a fatigue app that we developed for this study. Sleep was measured by a wrist actigraph.

Results
The average and SD of weekday DRPs was 13.1 ± 2.3 h. However, 54.5% of employees experienced less than the minimum 11-hour DRP at least once a month. Sleep duration was significantly changed with weekday DRPs, though no significant difference was found in sleep efficiency. Linear mixed effects models showed that sleep duration increased by approximately 15 minutes for each hour of weekday DRPs (β = 0.24, 95% CI; 0.17, 0.32, p &lt;.001). VAS-measured fatigue and psychological detachment from work significantly improved as DRPs increased (β = −3.4, 95% CI; −4.7, −2.1, p &lt;.001; β = 2.6, 95% CI; 1.2, 4.0, p &lt;.001, respectively). However, PVT performance did not significantly change with weekday DRPs.

Conclusions
Ensuring weekday DRPs plays an essential role in protecting the opportunities to sleep, with better recovery from fatigue and stress among information technology workers.
A Phase Ib/II Study of the JAK1 Inhibitor, Itacitinib, plus nab-Paclitaxel and Gemcitabine in Advanced Solid Tumors
Authors: Beatty Gregory L. , Shahda Safi , Beck Thaddeus , Uppal Nikhil , Cohen Steven J. , Donehower Ross , Gabayan Afshin Eli , Assad Albert , Switzky Julie , Zhen Huiling , Von Hoff Daniel D. 
Published: August 2018

Abstract

Lessons Learned
Itacitinib in combination with nab-paclitaxel plus gemcitabine demonstrated an acceptable safety profile with clinical activity in patients with advanced solid tumors including pancreatic cancer. The results support future studies of itacitinib as a component of combination regimens with other immunologic and targeted small molecule anticancer agents.

Background
Cytokine-mediated signaling via JAK/STAT is central to tumor growth, survival, and systemic inflammation, which is associated with cancer cachexia, particularly in pancreatic cancer. Because of their centrality in the pathogenesis of cancer cachexia and progression, JAK isozymes have emerged as promising therapeutic targets. Preclinical studies have demonstrated antiproliferative effects of JAK/STAT pathway inhibition in both in vitro and in vivo models of cancer, including pancreatic cancer.

Methods
This phase Ib/II dose-optimization study assessed itacitinib, a selective JAK1 inhibitor, combined with nab-paclitaxel plus gemcitabine in adults with treatment-naïve advanced/metastatic disease (Part 1) or pancreatic adenocarcinoma (Parts 2/2A; NCT01858883). Starting doses (Part 1) were itacitinib 400 mg, nab-paclitaxel 125 mg/m2, and gemcitabine 1,000 mg/m2. Additional dose levels incorporated were granulocyte colony-stimulating factor, de-escalations of itacitinib to 300 mg once daily (QD), nab-paclitaxel to 100 mg/m2, and gemcitabine to 750 mg/m2.

Results
Among 55 patients in Part 1, 6 developed seven hematologic dose-limiting toxicities (Cycle 1). Itacitinib 300 mg plus nab-paclitaxel 125 mg/m2 and gemcitabine 1,000 mg/m2 was tolerated and expanded in Part 2. Treatment discontinuation and grade 3/4 neutropenia rates prompted itacitinib de-escalation to 200 mg QD in Part 2A. The most common grade 3/4 toxicities were fatigue and neutropenia. Partial responses occurred across all itacitinib doses and several tumor types (overall response rate, 24%).

Conclusion
Itacitinib plus chemotherapy demonstrated acceptable safety and clinical activity in patients with advanced solid tumors including pancreatic cancers. This study was terminated early (sponsor's decision) based on negative phase III results for a JAK1/2 inhibitor in previously treated advanced pancreatic cancer.
Revisión legal y jurisprudencial del fuero de personas con discapacidad física, psíquica o sensorial
Authors: Rodríguez Lascarro Luz Mery 
Published: August 2018

El artículo 53 de nuestra Constitución actual, consagra unos principios mínimos fundamentales, que deberán estar siempre presentes en las relaciones laborales, con el fin de brindar protección y superiores garantías a los trabajadores, esto acompañado de la expedición de jurisprudencia garantista por parte de la Corte Constitucional, quien al resolver los casos que por tutela deben ser sometidos a esa corporación para su eventual revisión. Entre los principios (Valencia, H., 2007) allí consagrados, encontramos el de “estabilidad en el empleo”, (p. 220) del cual de acuerdo a las necesidades en materia laboral se han creado los llamados fueros de protección laboral, blindando al trabajador que por encontrarse en un estado de debilidad manifiesta no puede ser despedido sin el cumplimiento previo de un trámite especial para que proceda su desvinculación laboral.
De allí surge el de “La estabilidad laboral reforzada o fuero de personas con discapacidad física, psíquica y sensorial”, es un beneficio que tienen los trabajadores que por su situación de salud, se encuentran en estado de debilidad manifiesta o vulnerabilidad y que evita que puedan ser despedidos sin que sea agotado el debido proceso, en este caso el permiso de la autoridad competente en lo laboral como es el inspector del trabajo, pues de lo contrario se considera que el despido es ineficaz.
El valor intangible de la cláusula de estilo en los métodos alternos de solución de conflictos
Authors: Gorjón Francisco , Adame Melissa 
Published: August 2018

La implementación de los métodos alternos en específico el arbitraje comercial en la solución de conflictos internacionales derivados de compromisos comerciales, es una realidad, se ha convertido en una práctica común de las lex mercatoria la introducción de cláusulas arbitrales en todo contrato, elevándose estas a ser consideradas una cláusula de estilo de todo contrato internacional, rebasando la práctica comercial e introduciéndose en todo tipo de contrato. Con reconocimiento y valides legal en todo el orbe, respaldada por la lex fori y por el ius mercatorum.
Entendiéndose esta como un contrato independiente del contrato principal, sustentado su reconocimiento por la convención de New York del 58. Es por ello que se le considera un valor intangible de los MASC en específico del arbitraje, permitiendo que las partes puedan resolver sus conflictos en un ámbito privado, como principal ganancia, valor intrínseco y rasgo distintivo de esta cláusula de estilo.
DESEMPENHO AGRONÔMICO DE HÍBRIDOS DE SORGO BIOMASSA NAS CONDIÇÕES EDAFOCLIMÁTICAS DO TOCANTINS
Authors: Fortes Caio , Evaristo Anderson Barbosa , Barros Angélica , Pimentel Leonardo Duarte 
Published: August 2018

Objetivou-se com este trabalho avaliar o desempenho agronômico de híbridos de sorgo biomassa sensíveis e insensíveis ao fotoperíodo, cultivados em segunda safra, nas condições edafoclimáticas do estado de Tocantins (TO). Foram avaliados sete materiais genéticos de sorgo biomassa, dois sensíveis e cinco insensíveis ao fotoperiodismo, em três densidades de semeadura no município de Palmas. Objetivou-se avaliar diferenciado dos materiais quanto ao desempenho agronômico. Os híbridos de sorgo biomassa insensíveis ao fotoperíodo foram superiores quando comparados aos materiais sensíveis, isso em relação à altura de plantas, diâmetro dos colmos e número de entrenós. Além disso, apresentaram menor incidência de doenças foliares e maiores estandes de plantas, tanto aos 30 dias após a semeadura quanto na colheita. Os híbridos de sorgo biomassa insensíveis ao fotoperíodo tiveram maior produção de massa fresca e seca, mesmo em condições de intensa restrição hídrica ocorrida durante o ciclo. Os materiais mais promissores foram HFIS4 e HSBG1, com produtividades de massa seca de 8 Mg ha-1.PALAVRAS-CHAVE: Sorghum bicolor; população de plantas; safrinha, bioenergia, sorgo biomassa. AGRONOMIC PERFORMANCE OF BIOMASS SORGHUM HYBRIDS AT EDAPHOCLIMATIC CONDITIONS OF TOCANTINS STATEABSTRACT: The objective of this work was to evaluate the agronomic performance of sorghum hybrids that are sensitive and insensitive to the photoperiod, cultivated during winter season in Tocantins state, Brazil. Seven biomass sorghum genotypes, two sensitive and five insensitive to photoperiod were evaluated at three sowing populations in Palmas. It was observed different behavior among the materials, regarding agronomic performance. The biomass sorghum hybrids insensitive to photoperiod were better than sensitive materials in relation to plant height, stalk diameter, and number of internodes. In addition, they had lower incidence of foliar diseases and higher plant stands both 30 days after sowing and at harvest. Insensitive sorghum hybrids yielded higher fresh and dry mass production even under an intense water deficit conditions that occurred during the cycle. The most promising materials were HFIS4 and HSBG1 with dry mass yields of 8 Mg ha-1.KEYWORDS: Sorghum bicolor; plant population; winter season, bioenergy, biomass sorghum.
PRODUÇÃO DE PASTA CELULÓSICA E PAPEL DO PSEUDOCAULE DE BANANEIRA (Musa sp)
Authors: Pimentel Caroline Tosetto , Andrade Azarias Machado de , Dias Júnior Ananias Francisco 
Published: August 2018

Este estudo teve por objetivo avaliar o rendimento da conversão do pseudocaule de bananeira (Musa sp) em pasta celulósica. As pastas celulósicas, produzidas pelo processo soda, foram utilizadas na confecção de papéis, que foram comparados entre si, considerando-se características físicas e ópticas, como o fundo de impressão, a lisura e os aspectos superficiais. Foram avaliados os tempos de cozimento de 30 e 60 minutos e concentrações de hidróxido de sódio (NaOH) no licor de cozimento de 0; 1,5; 2,0 e 2,5%. Foi observado que os papéis produzidos das pastas sem adição de NaOH ao licor de cozimento são indicados para fins ornamentais, produção de sacolas e embalagens. Porém, não servem para a produção de papéis para impressão e escrita, pois apresentaram altos teores de rejeitos, com elevadas granulometrias. As folhas de papel da pasta celulósica obtida a partir do tratamento em que se adotou 60 minutos de cozimento e concentração de 2,5% de hidróxido de sódio foram, sob os pontos de vista físico e óptico, as melhores para impressão e escrita, além de apresentarem uma maior facilidade de formação, quando comparadas às demais.PALAVRAS CHAVE: Papel De Bananeira, Polpação Soda, Papel Artesanal. PRODUCTION OF CELLULOSIC PULP AND PAPER FROM BANANA (Musa sp) PSEUDOSTALK ABSTRACT: The objective of this study was to evaluate the efficiency of conversion banana (Musa sp) pseudostakl in cellulose pulp. The cellulosic pulps produced by soda process were used to produce papers using different methods. All papers were compared considering physical and optical characteristics such as printing background, smoothness and surface aspects. We analyzed cooking times of 30 and 60 minutes and concentrations of sodium hydroxide in the cooking liquor from 0%; 1.5%; 2.0% and 2.5%. It was observed that the papers produced from pastes without addition of NaOH are indicated for ornamental purposes, production of bags and packaging. However, they may not be used for production of printing and writing papers, since they have high contents of tailings, with high granulometry. The treatment with 60 minutes of cooking and 2.5% of sodium hydroxide concentration resulted in papers physically and optically best for printing and writing, in addition easier to product, when compared to the others.KEYWORDS: Banana Pseudostalk Paper, Sodium Hydroxide Cooking, Craft Paper.
Produção de forragem, morfogênese e eficiência agronômica do adubo em capim BRS Quênia sob doses de nitrogênio
Authors: Martuscello J. A. , Ribeiro Y. N. , Braz T. G. S. , Ferreira M. R. , Assis J. A. , Jank L. , Reis G. A. 
Published: August 2018

A adubação nitrogenada modifica os padrões morfogênicos de crescimento das forrageiras. Logo, estudos sobre a resposta de plantas recém lançadas, como a capim BRS Quênia, à adubação podem contribuir sobremaneira com a recomendação estratégias de manejo e doses mais apropriadas do adubo. Objetivou-se com este trabalho avaliar a alocação de biomassa aérea e radicular, resposta morfogênica e a eficiência agronômica da adubação em plantas de Panicum maximum cv. BRS Quênia, sem adubação e adubadas com 50, 100 e 200 mg.dm-3 de nitrogênio. O experimento foi conduzido em casa de vegetação, em delineamento inteiramente casualizado com quatro repetições. As proporções de folha foram maiores que as proporções de colmo, independentemente da adubação nitrogenada. Houve maiores incrementos na produção de parte aérea em detrimento a produção de raiz. O aumento da adubação implicou em menor intervalo entre o surgimento das folhas do capim BRS Quênia, bem como aumentou o número de perfilhos por planta. A medida que se incrementa a adubação nitrogenada há diminuição da eficiência de uso do adubo. A adubação nitrogenada influencia positivamente a produção de forragem em plantas de Panicum maximum BRS Quênia e, independentemente da dose de adubação nitrogenada, a parte aérea funciona como principal dreno de nitrogênio.
Entre uma seta e um círculo: algumas considerações sobre o tempo em Baudelaire
Authors: Barros Alice Vieira 
Published: August 2018

Este artigo objetiva construir uma leitura da poética de Baudelaire tomando como base a relação entre o “eu poético baudelairiano” e a História. Escolhi como principais aportes teóricos e ferramentas de leitura as reflexões do filósofo Walter Benjamin nas “Teses sobre o conceito de história”, que são avessas a um historicismo tradicional e linear e possuem muitos pontos de tangência com as ideias baudelairianas, e o ensaísmo crítico da poeta russa Marina Tsvetáieva, com suas considerações a respeito da relação entre o “poeta e o tempo”. Tencionamos desenvolver a hipótese segundo a qual a nostalgia do tempo mítico – por oposição a um tempo profano – configura, em Baudelaire, uma resposta crítica aos automatismos sobre a visão de progresso vigentes em seu contexto cultural, mediante a retomada consciente que o poeta faz de símbolos e mitemas da narrativa bíblica judaico-cristã.