bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inaugural issue perspectives onInformation and Learning Sciencesas an integral scholarly nexus
Authors: Reynolds Rebecca , Chu Sam , Ahn June , Buckingham Shum Simon , Hansen Preben , Haythornthwaite Caroline , Huang Hong , Meyers Eric M. , Rieh Soo Young 
Published: January 2019

PurposeMany of today’s information and technology systems and environments facilitate inquiry, learning, consciousness-raising and knowledge-building. Such platforms include e-learning systems which have learning, education and/or training as explicit goals or objectives. They also include search engines, social media platforms, video-sharing platforms, and knowledge sharing environments deployed for work, leisure, inquiry, and personal and professional productivity. The new journal,Information and Learning Sciences, aims to advance our understanding of human inquiry, learning and knowledge-building across such information, e-learning, and socio-technical system contexts.Design/methodology/approachThis article introduces the journal at its launch under new editorship in January, 2019. The article, authored by the journal co-editors and all associate editors, explores the lineage of scholarly undertakings that have contributed to the journal's new scope and mission, which includes past and ongoing scholarship in the following arenas: Digital Youth, Constructionism, Mutually Constitutive Ties in Information and Learning Sciences, and Searching-as-Learning.FindingsThe article offers examples of ways in which the two fields stand to enrich each other towards a greater holistic advancement of scholarship. The article also summarizes the inaugural special issue contents from the following contributors: Caroline Haythornthwaite; Krista Glazewski and Cindy Hmelo-Silver; Stephanie Teasley; Gary Marchionini; Caroline R. Pitt; Adam Bell, Rose Strickman and Katie Davis; Denise Agosto; Nicole Cooke; and Victor Lee.Originality/valueThe article, this special issue, and the journal in full, are among the first formal and ongoing publication outlets to deliberately draw together and facilitate cross-disciplinary scholarship at this integral nexus. We enthusiastically and warmly invite continued engagement along these lines in the journal’s pages, and also welcome related, and wholly contrary points of view, and points of departure that may build upon or debate some of the themes we raise in the introduction and special issue contents.
Lean maturity and quality in primary care
Authors: Kaltenbrunner Monica , Mathiassen Svend Erik , Bengtsson Lars , Engström Maria 
Published: January 2019

Purpose
The purpose of this paper is twofold: first, to describe Lean maturity in primary care using a questionnaire based on Liker’s description of Lean, complemented with observations; and second, to determine the extent to which Lean maturity is associated with quality of care measured as staff-rated satisfaction with care and adherence to national guidelines (NG). High Lean maturity indicates adoption of all Lean principles throughout the organization and by all staff.

Design/methodology/approach
Data were collected using a survey based on Liker’s four principles, divided into 16 items (n=298 staff in 45 units). Complementary observations (n=28 staff) were carried out at four units.

Findings
Lean maturity varied both between and within units. The highest Lean maturity was found for “adhering to routines” and the lowest for “having a change agent at the unit.” Lean maturity was positively associated with satisfaction with care and with adherence to NG to improve healthcare quality.

Practical implications
Quality of primary care may benefit from increasing Lean maturity. When implementing Lean, managers could benefit from measuring and adopting Lean maturity repeatedly, addressing all Liker’s principles and using the results as guidance for further development.

Originality/value
This is one of the first studies to evaluate Lean maturity in primary care, addressing all Liker’s principles from the perspective of quality of care. The results suggest that repeated actions based on evaluations of Lean maturity may help to improve quality of care.
Juvenile case of multiple morphea profunda resulting in joint contracture that was successfully treated with cyclosporin A: A case report and review of the published works
Authors: Ogawa Tatsuya , Okiyama Naoko , Takamuki Risa , Inoue Sae , Saito Akimasa , Nakamura Yoshiyuki , Ishitsuka Yosuke , Watanabe Rei , Fujisawa Yasuhiro , Fujimoto Manabu 
Published: January 2019

AbstractMorphea profunda refers to inflammatory and sclerotic lesions that start primarily from the deep dermis, subcutaneous fat and fascia. Its pediatric case published work is limited. Here, we report the case of an 8‐year‐old girl with a 5‐year history of multiple subcutaneous nodules on her extremities and a right wrist joint contracture who had been previously diagnosed with juvenile idiopathic arthritis and treated with salazosulfapyridine, low‐dose prednisolone (PSL) and methotrexate. We performed biopsies of two subcutaneous nodules, which revealed the typical morphology of morphea profunda. She was administrated a tapered course of oral PSL then cyclosporin A (CyA) for 20 weeks which completely resolved her joint contracture and subcutaneous nodules. We reviewed 11 previously reported cases of morphea profunda and found that some include circumscribed/linear morphea that develop into subcutaneous tissues, indicating that “classical” morphea profunda arising within the deep tissues has rarely been reported. Our report is the first to demonstrate the efficacy of CyA for treatment of morphea profunda, and the possibility of CyA as a treatment option to reduce oral steroid doses in juvenile cases.
Only Time Can Tell: Whether and When the Improvement in Career Development Opportunities Alleviates Knowledge Workers’ Emotional Exhaustion in the Chinese Context
Authors: Gao Zhonghua , Zhao Chen , Cooke Fang Lee , Zhang Bo , Xie Rongyan 
Published: January 2019

AbstractThrough extending the resource perspective, drawing on the temporal comparison theory, this study examines career development opportunities (CDOs), focusing on knowledge workers and considering the relative changes in CDOs before and after their job change in the Chinese context. Findings from a survey of 379 Chinese knowledge workers who have transferred their jobs at least once reveal that the improvement of CDOs can have a double‐edged‐sword effect on knowledge workers’ well‐being, shown as emotional exhaustion in this study. Although the improvement of CDOs negatively predicts knowledge workers’ emotional exhaustion in general, findings of a three‐way interaction reveal that offering more high‐quality CDOs can aggravate emotional exhaustion when knowledge workers have been working in their present position for a relatively long period, but have not received a pay rise. This study makes a theoretical contribution by introducing boundary conditions and testing their interactive influence. It helps broaden understanding of how CDOs can affect knowledge workers’ emotional exhaustion. It also has implications for enhancing the well‐being of knowledge workers, particularly in national and organizational contexts where there are significant skill shortages and retention problems.
Placing Arts Districts within Markets: A Case Study of 798 Arts District in Beijing
Authors: Zhang Amy Y. 
Published: January 2019

AbstractThis article examines the dual role of arts districts as places situated simultaneously in the urban land and art markets. It highlights the need for research into arts districts to take this dual role into account, as well as the impact that the two markets can have on these places. While the impact of the art market on land values in arts districts has been studied in some cases of art‐led gentrification, there has been limited consideration of how the changing organization and structure of the art world and art market have affected these places, especially during the last decade. Through a case study of 798 Arts District in Beijing, China, this article demonstrates that both land value and the art market situation need to be taken into account when explaining changes to and/or the spatial stickiness of an art scene, and that an artist community's investment in the value of an arts district as a generator of symbolic capital in the art market could be one driver of land value. The article concludes by advocating for greater attention to the dual market role of arts districts, as well as a stronger engagement with the knowledge produced by art scholars in geographical and urban studies of arts districts.
Intra‐amniotic digoxin for feticide between 21 and 30 weeks of gestation: a prospective study
Authors: Sharvit M , Klein Z , Silber M , Pomeranz M , Agizim R , Schonman R , Fishman A 
Published: January 2019

ObjectiveIntra‐amniotic injection of digoxin is a well‐known method for feticide before inducing a termination of pregnancy (TOP) at 17–24 weeks of gestation. Information on its effectiveness when administered after 24 weeks of gestation is limited. This study evaluated the efficacy of intra‐amniotic digoxin injection for inducing fetal demise within 18–24 hours, at 21–30 weeks of gestation, and its safety.DesignProspective cohort study.SettingTertiary university medical centre.PopulationWomen at 21–30 weeks of gestation with a singleton pregnancy, admitted for TOP.MethodsIntra‐amniotic injection of 2 mg of digoxin was performed 1 day before medical TOP. Fetal heart activity was evaluated by ultrasound for 18–24 hours after the injection. Serum digoxin level and maternal electrocardiogram (ECG) were evaluated 6, 10, and 20 hours after injection.Main outcome measureFrequency of successful fetal demise.ResultsFifty‐nine women participated in the study. The mean gestational age was 24+2 weeks (range 21+0–30+0), with 29 (49.2%) beyond 24+0 weeks of gestation. Fetal cardiac activity arrest was achieved in 55/59 cases (93.2%). Normal maternal ECG recordings were noted in all cases. Mean serum digoxin levels 6 and 10 hours after injection were in the therapeutic range (1.3 ± 0.7 ng/l and 1.24 ± 0.49 ng/l, respectively) and below the toxic level (2 ng/l). Extramural delivery following digoxin did not occur. There were no cases of chorioamnionitis.ConclusionIntra‐amniotic digoxin for feticide at 21–30 weeks of gestation in a singleton pregnancy appears effective and safe before TOP at advanced gestational ages.Tweetable abstractThis study shows that feticide by intra‐amniotic digoxin injection at 21–30 weeks of gestation appears effective and safe.
Public open space exposure measures in Australian health research: a critical review of the literature
Authors: Lamb Karen E. , Mavoa Suzanne , Coffee Neil T. , Parker Kate , Richardson Elizabeth A. , Thornton Lukar E. 
Published: January 2019

AbstractNumerous studies have shown associations between public open space and a variety of health outcomes. Yet the extent to which firm conclusions and planning policy recommendations can be drawn from this body of work depends on how public open space availability has been measured and reported. Other researchers have highlighted potential issues with the way that public open space has been measured but have not systematically assessed the extent of this problem. This paper provides a comprehensive critical review of studies of public open space and health conducted in Australia to identify and compare public open space measurement and data treatment. Our analysis showed wide variation in how public open space was measured, as well as a lack of consistency in reporting public open space exposure measures and under‐reporting of measurement methods. We find that such tendencies limit how much these studies can be compared and contrasted with each other. The corollary of that finding is that without more detailed reporting of exposure measures, it will be difficult to establish an evidence base that informs planning for healthy, liveable environments. In response, we develop and present a checklist for reporting public open space exposure to address this challenge.
In silico prospection of microorganisms to produce polyhydroxyalkanoate from whey: Caulobacter segnis DSM 29236 as a suitable industrial strain
Authors: Bustamante Daniel , Segarra Silvia , Tortajada Marta , Ramón Daniel , del Cerro Carlos , Auxiliadora Prieto María , Iglesias José Ramón , Rojas Antonia 
Published: January 2019

SummaryPolyhydroxyalkanoates (PHAs) are polyesters of microbial origin that can be synthesized by prokaryotes from noble sugars or lipids and from complex renewable substrates. They are an attractive alternative to conventional plastics because they are biodegradable and can be produced from renewable resources, such as the surplus of whey from dairy companies. After an in silico screening to search for ß‐galactosidase and PHA polymerase genes, several bacteria were identified as potential PHA producers from whey based on their ability to hydrolyse lactose. Among them, Caulobacter segnis DSM 29236 was selected as a suitable strain to develop a process for whey surplus valorization. This microorganism accumulated 31.5% of cell dry weight (CDW) of poly(3‐hydroxybutyrate) (PHB) with a titre of 1.5 g l−1 in batch assays. Moreover, the strain accumulated 37% of CDW of PHB and 9.3 g l−1 in fed‐batch mode of operation. This study reveals this species as a PHA producer and experimentally validates the in silico bioprospecting strategy for selecting microorganisms for waste re‐valorization.
Measuring global fish species richness with eDNA metabarcoding
Authors: Jerde Christopher L. , Wilson Emily A. , Dressler Terra L. 
Published: January 2019

AbstractDespite mounting threats to global freshwater and marine biodiversity, including climate change, habitat alteration, overharvesting and pollution, we struggle to know which species are present below the water's surface that are suffering from these stressors. However, the idea that a water sample containing environmental DNA (eDNA) can be screened using high‐throughput sequencing and bioinformatics to reveal the identity of aquatic species is a revolutionary advance for studying the patterns of species extirpation, invasive species establishment and the dynamics of species richness. To date, many of the critical tests of fisheries diversity using this metabarcoding approach have been conducted in lower diversity systems (<40 fish species), but in this issue of Molecular Ecology Resources, Cilleros et al. (2018) described their eDNA application in the species‐rich French Guiana fishery (>200 fish species) and showed the greater potential and some limitations of using eDNA in species‐rich environments.
Plant DNA‐barcode library and community phylogeny for a semi‐arid East African savanna
Authors: Gill Brian A. , Musili Paul M. , Kurukura Samson , Hassan Abidikadir A. , Goheen Jacob R. , Kress W. John , Kuzmina Maria , Pringle Robert M. , Kartzinel Tyler R. 
Published: January 2019

AbstractApplications of DNA barcoding include identifying species, inferring ecological and evolutionary relationships between species, and DNA metabarcoding. These applications require reference libraries that are not yet available for many taxa and geographic regions. We collected, identified, and vouchered plant specimens from Mpala Research Center in Laikipia, Kenya, to develop an extensive DNA‐barcode library for a savanna ecosystem in equatorial East Africa. We amassed up to five DNA barcode markers (rbcL, matK, trnL‐F, trnH–psbA, and ITS) for 1,781 specimens representing up to 460 species (~92% of the known flora), increasing the number of plant DNA barcode records for Africa by ~9%. We evaluated the ability of these markers, singly and in combination, to delimit species by calculating intra‐ and interspecific genetic distances. We further estimated a plant community phylogeny and demonstrated its utility by testing if evolutionary relatedness could predict the tendency of members of the Mpala plant community to have or lack “barcode gaps”, defined as disparities between the maximum intra‐ and minimum interspecific genetic distances. We found barcode gaps for 72%–89% of taxa depending on the marker or markers used. With the exception of the markers rbcL and ITS, we found that evolutionary relatedness was an important predictor of barcode‐gap presence or absence for all of the markers in combination and for matK, trnL‐F, and trnH–psbA individually. This plant DNA barcode library and community phylogeny will be a valuable resource for future investigations.
Predators and pastoralists: how anthropogenic pressures inside wildlife areas influence carnivore space use and movement behaviour
Authors: Broekhuis F. , Madsen E. K. , Klaassen B. 
Published: January 2019

AbstractAcross the globe, wildlife populations and their behaviours are negatively impacted by people. Protected areas are believed to be an antidote to increasing human pressures but even they are not immune to the impact of anthropogenic activities. Areas that have been set aside for the protection of wildlife therefore warrant more attention when investigating the impact of anthropogenic pressures on wildlife. We use cheetahs Acinonyx jubatus as a case study to explore how a large carnivore responds to anthropogenic pressures inside wildlife areas. Using GPS‐collar data we investigate cheetah space use, both when moving and stationary, and movement parameters (speed and turn angles) in relation to human disturbance, distance to human settlement, livestock abundance and livestock site use inside wildlife areas. Space use was negatively influenced by human disturbance, resulting in habitat loss and fragmentation and potentially reducing landscape permeability between neighbouring wildlife areas. Cheetahs were also less likely to stop in areas where livestock numbers were high, but more likely to stop in areas that were frequently used by livestock. The latter could reflect that cheetahs are attracted to livestock however, cheetahs in the study area rarely predated on livestock. It is therefore more likely that areas that are frequently used by livestock attract wild herbivores, which in turn could influence cheetah space use. We did not find any effects of people and livestock on cheetahs’ speed and turn angles which might be related to the resolution of the data. We found that cheetahs are sensitive to human pressures and we believe that they could be an indicator species for other large carnivores facing similar challenges. We suggest that further research is needed to determine the levels of anthropogenic pressures needed to maintain ecological integrity, especially inside wildlife areas.
A new classification system for describing concurrent use of nicotine vaping products alongside cigarettes (so‐called ‘dual use’): findings from the ITC‐4 Country Smoking and Vaping wave 1 Survey
Authors: Borland Ron , Murray Krista , Gravely Shannon , Fong Geoffrey T. , Thompson Mary E. , McNeill Ann , O'Connor Richard J. , Goniewicz Maciej L. , Yong Hua‐Hie , Levy David T. , Heckman Bryan W. , Cummings K. Michael 
Published: January 2019

AbstractAimsTo determine whether a simple combination of level of smoking and level of vaping results in a useful typology for characterizing smoking and vaping behaviours.MethodsCross‐sectional data from adults (≥ 18 years) in the 2016 wave 1 ITC Four Country Smoking and Vaping Survey in the United States (n = 2291), England (n = 3591), Australia (n = 1376) and Canada (n = 2784) were used. Participants who either smoked, vaped or concurrently used both at least monthly were included and divided into eight groups based on use frequency of each product (daily, non‐daily, no current use). This resulted in four concurrent use groups (predominant smokers, dual daily users, predominant vapers and concurrent non‐daily users). These groups were compared with each other and with the four exclusive use groups, on socio‐demographics, nicotine dependence, beliefs and attitudes about both products, and quit‐related measures using data weighted to reference population surveys in each country.ResultsOf the sample, 10.8% were concurrent users, with daily smokers vaping non‐daily (predominant smokers), constituting 51.6% of this group. All eight categories differed from other categories on at least some measures. Concurrent daily nicotine users reported higher levels of indicators of nicotine dependence, and generally more positive attitudes toward both smoking and vaping than concurrent non‐daily users. Among daily nicotine users, compared with exclusive daily smokers, reports of interest in quitting were higher in all concurrent use groups. Dual daily users had the most positive attitudes about smoking overall, and saw it as the least denormalized, and at the same time were equally interested in quitting as other concurrent users and were most likely to report intending to continue vaping.ConclusionsIn Australia, Canada, England and the United States in 2016, daily nicotine users differed considerably from non‐daily nicotine users. Among daily nicotine users, dual daily users (those who smoke and vape concurrently) should be treated as a distinct grouping when studying relationships between smoking and vaping. The eight‐level typology characterizing concurrent and exclusive use of smoking and vaping should be considered when studying both products.
Association between neighbourhood convenience stores and independent living in older people in Japan
Authors: Matsumoto Hiroshige , Igarashi Ayumi , Suzuki Miho , Yamamoto‐Mitani Noriko 
Published: January 2019

ObjectiveOn ageing, and as physical functionality declines, shopping for food and commodities can become a challenge. In Japan, convenience stores (CVSs) play an important role in older people's daily lives. This study investigated the relationship between the geographical accessibility of CVSs, supermarkets and grocery stores and shopping independence.MethodsWe used the administrative long‐term care insurance data from a sample of 7703 older adults. The spatial coverages of the stores were calculated using a geographic information system. A multilevel regression analysis was conducted to examine the association between neighbourhood spatial coverage and individual shopping independence.ResultsAfter adjusting for demographic characteristics, individual functioning and neighbourhood‐level population density, the regression analysis revealed that the CVSs spatial coverage was negatively associated with a risk of shopping dependence (odds ratio = 0.73, P = 0.03).ConclusionThe findings suggest that geographical accessibility of CVSs may be beneficial for maintaining shopping independence.
Validation study showed that ratings on the Welch Emotional Connection Screen at infant age six months are associated with child behavioural problems at age three years
Authors: Frosch Cynthia A. , Fagan Marcus A. , Lopez Mark A. , Middlemiss Wendy , Chang Mei , Hane Amie A. , Welch Martha G. 
Published: January 2019

AbstractAimThe emotional connection between mothers and infants born preterm has been associated with positive behaviour. The aim of this study was to examine the longitudinal association between emotional connection at six months of age and behavioural problems at three years.MethodsThis study was carried out by the University of North Texas, USA and comprised 49 mothers and infants from a longitudinal investigation of family interaction and infant development conducted in 1994–1997. Face‐to‐face interaction and toy‐based play were videotaped and coded at six months of age using the Welch Emotional Connection Screen (WECS), a brief screening tool for relational health. When the children were three years of age, the mothers reported on child behavioural problems.ResultsThe children from dyads that were rated as emotionally connected at six months of age had fewer externalising and internalising behavioural problems at the age of three. No links were found between emotional connection during toy‐based play at six months and later child behavioural problems.ConclusionWe showed that when the WECS was used at six months of age it was a promising and valid relational screening tool for infants at risk of adverse behavioural outcomes at the age of three.