bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mathematical Problem Posing Ability in Terms of Student Learning Styles
Authors: Puspitasari N , Suryadi D , Sumarmo U , Margana A 
Published: October 2019

Abstract
Asking question is an expression of the thought process. Question arises when someone gets new knowledge that is not in accordance with previous knowledge, through the thought process arises the question to get complete information so that the new knowledge he has becomes more meaningful. This study aims to evamine and analyze the ability of students in problem posing based on their learning style. The method carried out in this study was a quasi-experiment on 80 high-school students. The results showed that there is significant difference for the achievement of mathematical problem posing abilities based on visual, auditory, and kinesthetic learning styles, contrary there is no significant difference in the improvement mathematical problem posing skills based on visual, auditory, and kinesthetic learning styles
Cognitive Stage Relation with Creative Thinking Ability and Mathematical Learning Interests
Authors: Rohaeti E E , Ramadan B G , Fitriani N 
Published: October 2019

AbstractThis study aims to analyze the links between students’ cognitive stages and creative thinking skills and mathematical learning interests. This study involved 36 11th grade students, test of logical thinking (TOLT), a description of the creative thinking ability (CTA), learning interest scale (LI). Based on TOLT, the study found the cognitive stage distribution of students as follows: 30% of students were in the formal stage, 25% were transitional stages, and 45% were concrete stages. In addition, the researchers found, overall in CTA and LI students achieve quality at a fairly good level. Judging from the cognitive stage of students, the quality of CTA and LI students in the formal and transition stages is classified as a fairly good level, and concrete students achieve the quality of CTA and LI at moderate levels. In addition to completing the CTA tasks, concrete students experience more difficulties while the students in the transition stage and the formal stage experience a little difficulty. Another finding is that there is no association between CTA and LI. Overall, the findings relate to the cognitive stage, the quality of the CTA and LI students based on their cognitive stages according to the child’s Cognitive Development Theory.
The hard c-means algorithm for clustering Indonesian plantation commodity based on metabolites composition
Authors: Rustam  , Gunawan A Y , Kresnowati M T A P 
Published: October 2019

Abstract
Indonesia is the second largest biodiversity country in the world. Indonesia has a variety of top agricultural and plantation commodities, whereas each commodity has premium products which are normally related to its specific character/flavour and are generally associated with the producing origins. Specific character/flavour is represented by composition of metabolites each origin. To find out the specific character/flavour in various Indonesian plantation commodities, clustering is needed. In this paper, we perform clustering on an Indonesian plantation commodity based on their metabolites composition. Metabolite compositions of samples of some origins of the commodity are clustered using the Hard C-Means algorithm with the Xie-Beni index as the cluster validity. Our present results confirm that each origin has a unique characteristic and belongs to a separate cluster.
The development of teaching materials for secondary teachers based on 21stcentury skills
Authors: Sihabudin  , Anriani N , Fathurrohman M , Pamungkas A S , Irawan B 
Published: October 2019

AbstractThe purpose of this study was to produce Teaching Materials for secondary teachers based on 21st century skills aspecially for circle topic and to know the quality of teaching materials based on validity and practicability. This research is a development research that includes seven main steps, namely: needs analysis, the ability of researchers as developers, product design, product concepts, development, expert testing, and field trials. The feasibility of developing a teaching materials was obtained based on data from the questionnaire which was then analyzed descriptively quantitatively. The conclusion of this research is the teaching material for secondary teacher aspesially for circle topic based on 21st century skill fulfilling the minimum criteria and expressed very well from the validity aspects and in terms of practical aspects stated practical. Thus, the teaching materials for mathematics teachers based on 21st century skill can be used as a teacher’s guide on the learning process.
Jumping task using the context of kain jumputan on the fractional operation
Authors: Saskiyah SA , Putri RII 
Published: October 2019

Abstract
Jumping task is the central part of teaching that uses Higher Order Thinking Skills (HOTS). The revised 2013 Curriculum in Indonesia emphasizes learning using HOTS, and the daily life context. This research aimed to find out the characteristic of jumping tasks which valid, practical, and also useful for supporting secondary school students learning fractional operations using PMRI with the context of kain jumputan. The subject of this research was seventh-grade students of secondary school in Palembang. The research uses the method of design research with development studies type which had two stages: the preliminary and formative evaluation. This research only presented the result on self-evaluation, expert reviews and one-to-one, and small group phase. Data collection techniques using walkthrough, documentation, observation, and interviews. PMRI is used as material content and context for this research. Moreover, the Lesson Study for Learning Community (LSLC) is used in designing and implementing the learning process. The result of this research was produced mathematics problems about addition and subtraction fractional operations through the context of kain jumputan. This research is valid and practical jumping tasks on fractional operations using PMRI with the context of kain jumputan. Validity could be seen from the assessment of a validator (expert) regarding content, construct, and language used in the one-to-one phase. Practicality could be seen where the students could understand the language and the content of the questions that are in the jumping task. Thus, the context of kain jumputan can help students in representing problems by involving in mathematical expressions.
Characterisation of hanging and detaching droplets using optical measurement setups
Authors: Hummel S , Haub M , Bogner M , Sandmaier H 
Published: October 2019

Abstract
This paper presents two measurement setups to analyse hanging and falling droplets from different nozzles. The focus of these setups is on reducing costs and complexity of such systems compared to systems mentioned in literature which consists of an expensive high speed camera with according lens. Therefore the first setup uses an industrial camera and a corresponding lens having a resolution of up to 800 x 600 pixels and enabling the capturing of movies with more than 1000 frames per second (by using a reduced resolution). Additionally a weighing scale is implemented. The second setup represents a real low-cost approach, which nevertheless offers about 120 frames per second and a resolution of 640 × 480 pixels by using two RaspberryPi microcontrollers and the according camera modules. The cameras are placed in an angle of 90°. The presented setups are compared to each other and the advantages and disadvantages of each system are figured out. Subsequently the results of an exemplary measurement of the droplet volume are presented showing the quality of both setups with a maximum deviation of the optical results of less than ± 6 % compared to the results of the weighing scale.
Enhancement of real-time resonance tracking in electrothermally actuated cantilever sensor with optimized phase characteristic
Authors: Setiono A , Xu J , Fahrbach M , Bertke M , Ombati Nyang’au W , Wasisto H S , Peiner E 
Published: October 2019

Abstract
Non-ideal phase responses on electro-thermally actuated piezoresistive cantilever sensors have led the phase-locked loop (PLL) systems into difficulties for real-time sensing applications. These outcomes are caused by thermal-parasitic coupling from the actuating part to the sensing part. Minimizing or eliminating parasitic effects is necessary to obtain an optimized phase response. To realize this, we adjusted the voltage supply of the sensing part, which is in form of a full Wheatstone bridge (WB). By increasing the WB supply voltage (V
WB), the phase response can be enhanced. Alternatively, a reference signal that differentially eliminates the parasitic parameter from the sensor output was employed. To investigate the resulting optimized phase response under real-time measurement conditions, two different microcantilevers were connected to an MFLI lock-in amplifier + PLL system (Zurich Instruments). Measurement results exhibited a good sensor performance under varying humidity and temperature conditions.
Indentation modulus and hardness investigation of crystalline silicon surfaces treated by inductively coupled plasma reactive ion etching
Authors: Puranto Prabowo , Hamdana Gerry , Pohlenz Frank , Langfahl-Klabes Jannick , Daul Lars , Li Zhi , Wasisto Hutomo Suryo , Peiner Erwin , Brand Uwe 
Published: October 2019

Abstract
In this paper we present an investigation of the influence of different roughness of etched silicon surfaces on the measured nanomechanical properties. For the etching, inductively coupled plasma (ICP) reactive ion etching (RIE) was performed on the surface of silicon samples with different crystal orientations (i.e., Si <100>, Si <110>, and Si <111>). Different roughness levels were obtained on each sample by changing the bias voltage through the high-frequency (HF) power. The surface roughness was measured using atomic force microscopy (AFM). The obtained surface roughness for the same etching conditions was different for different crystal orientations. The nanomechanical properties were measured using nanoindentation.
Design and fabrication of AlN-on-Si chirped surface acoustic wave resonators for label-free cell detection
Authors: Syamsu I , Granz T , Scholz G , Mariana S , Yulianto N , Daul L , Koenders L , Triyana K , Daniel Prades J , Peiner E , Waag A , Wasisto H S 
Published: October 2019

Abstract
Chirped surface acoustic wave (SAW) resonators based on aluminum nitride (AlN) thin films have been designed and fabricated to comprehend the wave propagation characteristics induced by interdigitated transducers (IDTs) deposited on their surfaces. From the simulation results, design and geometry of the metal fingers including their width and pitch play critical roles on the wavelength of the acoustic wave and the mechanical displacement, which subsequently set the device resonant frequency. A single-step metal lift-off process involving photolithography and electron beam metal evaporation has been used to pattern and deposit Cr/Au IDT on AlN-on-Si wafers.
NITUMID: Nonnegative matrix factorization-based Immune-TUmor MIcroenvironment Deconvolution
Authors: Tang Daiwei , Park Seyoung , Zhao Hongyu 
Published: October 2019

Abstract

Motivation
A number of computational methods have been proposed recently to profile tumor microenvironment (TME) from bulk RNA data, and they have proved useful for understanding microenvironment differences among therapeutic response groups. However, these methods are not able to account for tumor proportion nor variable mRNA levels across cell types.

Results
In this article, we propose a Nonnegative Matrix Factorization-based Immune-TUmor MIcroenvironment Deconvolution (NITUMID) framework for TME profiling that addresses these limitations. It is designed to provide robust estimates of tumor and immune cells proportions simultaneously, while accommodating mRNA level differences across cell types. Through comprehensive simulations and real data analyses, we demonstrate that NITUMID not only can accurately estimate tumor fractions and cell types’ mRNA levels, which are currently unavailable in other methods; it also outperforms most existing deconvolution methods in regular cell type profiling accuracy. Moreover, we show that NITUMID can more effectively detect clinical and prognostic signals from gene expression profiles in tumor than other methods.

Availability and implementation
The algorithm is implemented in R. The source code can be downloaded at https://github.com/tdw1221/NITUMID.

Supplementary information
Supplementary data are available at Bioinformatics online.
ErrorTracer: an algorithm for identifying the origins of inconsistencies in genome-scale metabolic models
Authors: Martyushenko Nikolay , Almaas Eivind 
Published: October 2019

Abstract

Motivation
The number and complexity of genome-scale metabolic models is steadily increasing, empowered by automated model-generation algorithms. The quality control of the models, however, has always remained a significant challenge, the most fundamental being reactions incapable of carrying flux. Numerous automated gap-filling algorithms try to address this problem, but can rarely resolve all of a model’s inconsistencies. The need for fast inconsistency checking algorithms has also been emphasized with the recent community push for automated model-validation before model publication. Previously, we wrote a graphical software to allow the modeller to solve the remaining errors manually. Nevertheless, model size and complexity remained a hindrance to efficiently tracking origins of inconsistency.

Results
We developed the ErrorTracer algorithm in order to address the shortcomings of existing approaches: ErrorTracer searches for inconsistencies, classifies them and identifies their origins. The algorithm is ∼2 orders of magnitude faster than current community standard methods, using only seconds even for large-scale models. This allows for interactive exploration in direct combination with model visualization, markedly simplifying the whole error-identification and correction work flow.

Availability and implementation
Windows and Linux executables and source code are available under the EPL 2.0 Licence at https://github.com/TheAngryFox/ModelExplorer and https://www.ntnu.edu/almaaslab/downloads.

Supplementary information
Supplementary data are available at Bioinformatics online.
Characteristics of Pre-Proceedings and Care Proceedings Cases in an English Local Authority, 2013–2017: An Exploratory Data Analysis
Authors: Dyke Chris 
Published: October 2019

AbstractSince reforms in 2014, care proceedings—where a local authority seeks to intervene legally to protect a child—have become shorter, with greater emphasis on ‘front-loading’ preventative and analytical work before, rather than during, proceedings. National findings on case outcomes are emerging, but in-depth local analyses are still rare. This exploratory data analysis of 937 children in 522 families in one London local authority sought to identify trends in the length, outcome and nature of pre-proceedings and proceedings cases, including outcomes six, twelve and twenty-four months after the end of these processes. Consistent with national-level findings on care proceedings, from 2013 to 2017 both the pre-proceedings and care proceedings processes became shorter, and more likely to end with the child at home. The data do not suggest that this increased ‘decisiveness’ leads to rushed decisions. Only 1.4 per cent of the children stepped-down from pre-proceedings, and 6.6 per cent of the children who remained at home after care proceedings came into care within two years of that decision. This research offers a model for similar analyses by practitioner researchers within their own local authorities.
Far upstream element-binding protein 1 facilitates hepatocellular carcinoma invasion and metastasis
Authors: Fu Pei-Yao , Hu Bo , Ma Xiao-Lu , Tang Wei-Guo , Yang Zhang-Fu , Sun Hai-Xiang , Yu Min-Cheng , Huang Ao , Hu Jin-Wu , Zhou Chen-Hao , Fan Jia , Xu Yang , Zhou Jian 
Published: October 2019

AbstractPrevious research suggests that far upstream element-binding protein 1 (FUBP1) plays an important role in various tumors including epatocellular carcinoma (HCC). However, the role of FUBP1 in liver cancer remains controversial, and the regulatory pathway by FUBP1 awaits to be determined. This study aims to identify the role of FUBP1 in HCC progression. Our result shows that the high level of FUBP1 expression in HCC predicts poor prognosis after surgery. Overexpression of FUBP1 promotes HCC proliferation, invasion, and metastasis by activating transforming growth factor-β (TGF-β)/Smad pathway and enhancing epithelial-mesenchymal transition (EMT) in vitro and in vivo. Inhibitor of Thrombospondin-1 (LSKL) could inhibit HCC proliferation and invasion in vitro and in vivo by blocking the activation of TGF-β/Smad pathway mediated by thrombospondin-1 (THBS1). Our study identified the critical role of FUBP1-THBS1-TGF-β signaling axis in HCC and provides potentially new therapeutic modalities in HCC.
Development of Network Topology and Functional Connectivity of the Prefrontal Cortex
Authors: Lopez Katherine C , Kandala Sridhar , Marek Scott , Barch Deanna M 
Published: October 2019

AbstractThe prefrontal cortex (PFC) comprises distinct regions and networks that vary in their trajectories across development. Further understanding these diverging trajectories may elucidate the neural mechanisms by which distinct PFC regions contribute to cognitive maturity. In particular, it remains unclear whether PFC regions of distinct network affiliations differ in topology and their relationship to cognition. We examined 615 individuals (8–21 years) to characterize age-related effects in participation coefficient of 28 PFC regions of distinct networks, evaluating connectivity profiles of each region to understand patterns influencing topological maturity. Findings revealed that PFC regions of attention, frontoparietal, and default mode networks (DMN) displayed varying rates of decline in participation coefficient with age, characterized by stronger connectivity with each PFC’s respective network; suggesting that PFC regions largely aid network segregation. Conversely, PFC regions of the cinguloopercular/salience network increased in participation coefficient with age, marked by stronger between-network connections, suggesting that some PFC regions feature a distinctive ability to facilitate network integration. PFC topology of the DMN, in particular, predicted improvements in global cognition, including motor speed and higher order abilities. Together, these findings elucidate systematic differences in topology across PFC regions of different network affiliation, representing important neural signatures of typical brain development.
Childhood Obesity, Cortical Structure, and Executive Function in Healthy Children
Authors: Ronan Lisa , Alexander-Bloch Aaron , Fletcher Paul C 
Published: October 2019

Abstract
The development of executive function is linked to maturation of prefrontal cortex (PFC) in childhood. Childhood obesity has been associated with changes in brain structure, particularly in PFC, as well as deficits in executive functions. We aimed to determine whether differences in cortical structure mediate the relationship between executive function and childhood obesity. We analyzed MR-derived measures of cortical thickness for 2700 children between the ages of 9 and 11 years, recruited as part of the NIH Adolescent Brain and Cognitive Development (ABCD) study. We related our findings to measures of executive function and body mass index (BMI). In our analysis, increased BMI was associated with significantly reduced mean cortical thickness, as well as specific bilateral reduced cortical thickness in prefrontal cortical regions. This relationship remained after accounting for age, sex, race, parental education, household income, birth-weight, and in-scanner motion. Increased BMI was also associated with lower executive function. Reduced thickness in the rostral medial and superior frontal cortex, the inferior frontal gyrus, and the lateral orbitofrontal cortex partially accounted for reductions in executive function. These results suggest that childhood obesity is associated with compromised executive function. This relationship may be partly explained by BMI-associated reduced cortical thickness in the PFC.
Dissociable Mechanisms of Verbal Working Memory Revealed through Multivariate Lesion Mapping
Authors: Ghaleh Maryam , Lacey Elizabeth H , Fama Mackenzie E , Anbari Zainab , DeMarco Andrew T , Turkeltaub Peter E 
Published: October 2019

Abstract
Two maintenance mechanisms with separate neural systems have been suggested for verbal working memory: articulatory-rehearsal and non-articulatory maintenance. Although lesion data would be key to understanding the essential neural substrates of these systems, there is little evidence from lesion studies that the two proposed mechanisms crucially rely on different neuroanatomical substrates. We examined 39 healthy adults and 71 individuals with chronic left-hemisphere stroke to determine if verbal working memory tasks with varying demands would rely on dissociable brain structures. Multivariate lesion–symptom mapping was used to identify the brain regions involved in each task, controlling for spatial working memory scores. Maintenance of verbal information relied on distinct brain regions depending on task demands: sensorimotor cortex under higher demands and superior temporal gyrus (STG) under lower demands. Inferior parietal cortex and posterior STG were involved under both low and high demands. These results suggest that maintenance of auditory information preferentially relies on auditory-phonological storage in the STG via a nonarticulatory maintenance when demands are low. Under higher demands, sensorimotor regions are crucial for the articulatory rehearsal process, which reduces the reliance on STG for maintenance. Lesions to either of these regions impair maintenance of verbal information preferentially under the appropriate task conditions.