bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful use of veno‐arterial extracorporeal membrane oxygenation for septic cardiomyopathy in a patient with pre‐existing chronic heart failure
Authors: Wada Kenshiro , Bunya Naofumi , Kakizaki Ryuichiro , Kasai Takehiko , Uemura Shuji , Harada Keisuke , Narimatsu Eichi 
Published: March 2019

BackgroundIndications for using veno‐arterial extracorporeal membrane oxygenation (V‐A ECMO) in sepsis cases remain unclear.Case PresentationA 66‐year‐old man with pre‐existing chronic heart failure developed severe pneumonia resulting in refractory septic shock. He was diagnosed with septic cardiomyopathy based on depressed left ventricular ejection fraction and a dilated left ventricle based on a transthoracic echocardiogram. We initiated V‐A ECMO on day 3 because the shock did not respond to conventional therapy. The patient's hemodynamics improved, and his infection was reduced. He recovered fully and was discharged on day 107 with his cardiac function restored to its baseline.ConclusionSeptic cardiomyopathy is a form of reversible myocardial dysfunction. Veno‐arterial extracorporeal membrane oxygenation should be considered for septic cardiomyopathy with intractable circulatory failure. Pre‐existing chronic heart failure is not a contraindication for VA‐ECMO.
Silicon core–iron siloxane shell nanoparticle polymer composites with multiferroic properties
Authors: Aleksandrov A. I. , Shevchenko V. G. , Aleksandrov I. A. , Tebeneva N. A. , Meshkov I. B. , Kalinina A. A. , Degtyarev E. N. , Dubinskii A. A. , Kovarsky A. L. , Zezin S. B. , Krasovskii V. G. , Abramchuk S. S. , Buzin M. I. , Muzafarov A. M. 
Published: March 2019

ABSTRACTMultiferroic (MF) composites based on nanoparticles consisting of a silica core and a shell of spin‐variable Fe(III) complexes in a polymer matrix (polystyrene) were synthesized and characterized by different methods. The nanoparticles had the formula 80SiO2·20{Fe[OSi(Me)(OEt)2]3}, and their particle size was on the order of 5–7 nm. Dielectric and electron spin resonance studies showed the presence of two types of Fe ions in the nanocomposite. Iron ions in the low‐spin state [Fe(III)‐LS] and iron ions in the high‐spin state [Fe(III)‐HS], which were bound by indirect exchange interactions through oxygen and silicon atoms {[Fe(III)‐LS]─O─Si─O─[Fe(III)‐HS]} were responsible for the MF properties of the composites with core–shell nanoparticles. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47681.
Tough hybrid hydrogels based on simultaneous dual in situ sol–gel technique and radical polymerization
Authors: Du Juan , She Xiaohong , Zhu Wenli , Zhang Huaju , Deng Tao , Li Xiaoyu , Liu Jiayu , Li Mingtian 
Published: March 2019

ABSTRACTA tough hybrid hydrogel has been developed by dual in situ sol–gel reaction of γ‐ethacryloxypropyltrimethoxysilane (MPTMS) and tetrabutyl titanate, as well as in situ radical polymerization of acrylamide (AM) and MPTMS. In this hydrogel, covalently bonded SiO2 and TiO2 nanoparticles were used as inorganic filler and multifunctional crosslinker. Nano‐TiO2 was bonded onto the surface of SiO2 by forming TiOSi bonds and SiO2 bonded with polymer chains by the formation of COSi bonds, which were confirmed by Fourier transform infrared and X‐ray photoelectron spectroscopy technology. Transmission electron microscopy images revealed that SiO2 and TiO2 tended to construct a distinct rod‐like structure in poly(AM) matrix. This specific microstructure enhanced the mechanical properties of hydrogel. The compressive stress of the gel reached up to 9.49 MPa, and the compressive fracture energy was as high as 5307.73 J m−2. This strategy provided a probable method for the preparation of tough soft materials with potential applications in chemical machinery and actuators. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47742.
Synthesis and testing of cellulose acetate nicotinate as adsorbent for rhodamine B dye
Authors: Olaru Niculae , Anghel Narcis , Pascariu Petronela , Ailiesei Gabriela 
Published: March 2019

ABSTRACTThe esterification of cellulose hydroxyl groups with natural carboxylic acids in mild conditions represents an adequate pathway in obtaining cellulose derivatives with different useful properties. In this article, authors report the synthesis of new mixed ester of cellulose and cellulose acetate nicotinate (CAN) , in a homogenous medium using DMF as solvent, cellulose acetate (CA) as starting cellulosic material, and nicotinic acid as an esterification agent in the presence of p‐toluenesulfonyl chloride and pyridine. FTIR and NMR techniques were used to prove the binding of nicotinoyl group at free hydroxyl groups of CA. The obtained CAN was electrospun by electrospinning technique to obtain adsorbent ultrafine fibers, evidenced by SEM images, with high specific surface area. Monolayer Langmuir and empirical Leundrich isotherms were used to assess the adsorption capacity for rhodamine B dye of electrospun CAN in comparison with that of electrospun CA used as starting material. Langmuir isotherm led to a better assessment of experimental data suggesting that the adsorption is mainly determined by hydrogen bonds formed between carboxylic OH hydrogen bonding donor and pyridine N hydrogen bonding acceptor. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47772.
An Older and Exceptionally Large Adult Specimen of Tyrannosaurus rex
Authors: Persons W. Scott , Currie Philip J. , Erickson Gregory M. 
Published: March 2019

ABSTRACTHere we describe an extremely large and relatively complete (roughly 65%) skeleton of Tyrannosaurus rex (RSM P2523.8). Multiple measurements (including those of the skull, hip, and limbs) show that RSM P2523.8 was a robust individual with an estimated body mass exceeding all other known T. rex specimens and representatives of all other gigantic terrestrial theropods. Histological sampling of the fibula confirms that RSM P2523.8 is skeletally mature. The prevalence of incompletely coossified elements contradicts previous assertions that such unfused elements can be taken as indicators of somatic immaturity. As an extreme example of both ontogenetic maturity and osteological robustness, RSM P2523.8 offers support for prior hypotheses that a sampling bias occurs throughout the Dinosauria, making it likely that most taxa grew to significantly greater size than current known specimens indicate. Anat Rec, 303:656–672, 2020. © 2019 Wiley Periodicals, Inc.
Role of Nickel Nanoparticles in High‐Performance TiO2/Ni/Carbon Nanohybrid Lithium/Sodium‐Ion Battery Anodes
Authors: Wang Xiaoyan , Zhao Dong , Wang Chao , Xia Yonggao , Jiang Wenshuai , Xia Senlin , Yin Shanshan , Zuo Xiuxia , Metwalli Ezzeldin , Xiao Ying , Sun Zaicheng , Zhu Jin , Müller‐Buschbaum Peter , Cheng Ya‐Jun 
Published: March 2019

AbstractSuper‐small sized TiO2 nanoparticles are in situ co‐composited with carbon and nickel nanoparticles in a facile scalable way, using difunctional methacrylate monomers as solvent and carbon source. Good control over crystallinity, morphology, and dispersion of the nanohybrid is achieved because of the thermosetting nature of the resin polymer. The effects of the nickel nanoparticle on the composition, crystallographic phase, structure, morphology, tap density, specific surface area, and electrochemical performance as both lithium‐ion and sodium‐ion battery anodes are systematically investigated. It is found that the incorporation of the in situ formed nickel nanoparticles with certain content effectively enhances the electrochemical performance including reversible capacities, cyclic stability and rate performance as both lithium‐ion and sodium‐ion battery anodes. The experimental I‐V profiles at different temperatures and theoretical calculations reveal that the charge carriers are accumulated in the amorphous carbon regions, which act as scattering centers to the carriers and lower the carrier mobility for the composite. With increasing nickel content, the mobility of the charge carriers is significantly increased, while the number of the charge carriers maintains almost constant. The nickel nanoparticles provide extra pathways for the accumulated charge, leading to reduced scatterings among the charge carriers and enhanced charge‐carrier transportation.
Time‐Dependent Emission Enhancement of the Ethynylpyrene‐o‐Carborane Dyad and Its Application as a Luminescent Color Sensor for Evaluating Water Contents in Organic Solvents
Authors: Nishino Kenta , Yamamoto Hideki , Ochi Junki , Tanaka Kazuo , Chujo Yoshiki 
Published: March 2019

AbstractThe time‐dependent emission enhancement (TDEE) phenomena of the 1‐(o‐carboran‐1‐yl)ethynylpyrene dyad were reported. It was found that the emission intensity from the dyad increased in tetrahydrofuran (THF), acetone and dichloromethane with increasing incubation time. From the mechanistic studies, it was suggested that agglomeration of the dyad gradually proceeded in these media, followed by expression of excimer luminescence. Additionally, it was shown that the rates of TDEE of the dyad were sensitively accelerated in the presence of a trace amount of water. Based on this fact, a detection system for water contents in acetone was constructed. Before and after incubation for 96 h at room temperature, time courses of changes in optical properties were monitored. Finally, water contents in acetone can be estimated by the degrees of TDEE and emission color changes in the range from 0.1 wt % to 2.0 wt % and from 2.0 wt % to 20 wt %, respectively.
Student Understanding of DNA Structure–Function Relationships Improves from Using 3D Learning Modules with Dynamic 3D Printed Models
Authors: Howell Michelle E. , Booth Christine S. , Sikich Sharmin M. , Helikar Tomáš , Roston Rebecca L. , Couch Brian A. , van Dijk Karin 
Published: March 2019

AbstractUnderstanding the relationship between molecular structure and function represents an important goal of undergraduate life sciences. Although evidence suggests that handling physical models supports gains in student understanding of structure–function relationships, such models have not been widely implemented in biochemistry classrooms. Three‐dimensional (3D) printing represents an emerging cost‐effective means of producing molecular models to help students investigate structure–function concepts. We developed three interactive learning modules with dynamic 3D printed models to help biochemistry students visualize biomolecular structures and address particular misconceptions. These modules targeted specific learning objectives related to DNA and RNA structure, transcription factor‐DNA interactions, and DNA supercoiling dynamics. We also designed accompanying assessments to gauge student learning. Students responded favorably to the modules and showed normalized learning gains of 49% with respect to their ability to understand and relate molecular structures to biochemical functions. By incorporating accurate 3D printed structures, these modules represent a novel advance in instructional design for biomolecular visualization. We provide instructors with the materials necessary to incorporate each module in the classroom, including instructions for acquiring and distributing the models, activities, and assessments. © 2019 International Union of Biochemistry and Molecular Biology, 47(3):303–317, 2019.
A liquid chromatography–tandem mass spectrometry method to simultaneously determinate dichlorvos and phoxim in tobacco
Authors: Qin Xinxian , Luo Xiaoshuang , Chen Ye , Han Jiahua , Zhang Ji , Zhang Kankan , Hu Deyu 
Published: March 2019

AbstractA simple pretreatment method with liquid chromatography–tandem mass spectrometry (LC–MS/MS) was developed and validated to simultaneously determine dichlorvos and phoxim in tobacco and soil matrices. Satisfactory linearity (R2 ≥ 0.9991) of the method was obtained for both analytes. The limits of detection and limits of quantification for dichlorvos and phoxim in three matrices were 0.0015–0.006 and 0.005–0.02 mg/kg, respectively. Average recoveries were 78.24–92.21% for dichlorvos and 76.62–100.51% for phoxim in soil, green tobacco leaves and cured tobacco leaves. The intra‐ and inter‐day relative standard deviations were <6%. The established method was successfully applied for the residual analysis of dichlorvos and phoxim in real soil and tobacco samples. The results indicated that the established method could be used to detect trace amounts of dichlorvos and phoxim in tobacco. The data could also help the Chinese government establish maximum residue limits of dichlorvos and phoxim on tobacco and establish proper and safe use of dichlorvos and phoxim on tobacco plants in China.
Impact of immigration status on health behaviors and perceptions in cancer survivors
Authors: Liu Sophia Y. , Lu Lin , Pringle Dan , Mahler Mary , Niu Chongya , Charow Rebecca , Tiessen Kyoko , Lam Christine , Halytskyy Oleksandr , Naik Hiten , Hon Henrique , Irwin Margaret , Pat Vivien , Gonos Christina , Chan Catherine W. T. , Villeneuve Jodie , Shani Ravi M. , Chaudhry Maha , Brown M. Catherine , Selby Peter , Howell Doris , Xu Wei , Alibhai Shabbir M. H. , Jones Jennifer M. , Liu Geoffrey , Eng Lawson 
Published: March 2019

AbstractBackgroundHealth behaviors including smoking cessation, physical activity (PA), and alcohol moderation are key aspects of cancer survivorship. Immigrants may have unique survivorship needs. We evaluated whether immigrant cancer survivors had health behaviors and perceptions that were distinct from native‐born cancer survivors.MethodsAdult cancer patients from Princess Margaret Cancer Centre were surveyed on their smoking, PA, and alcohol habits and perceptions of the effects of these behaviors on quality of life (QoL), 5‐year survival, and fatigue. Multivariable models evaluated the association of immigration status and region‐of‐origin on behaviors and perceptions.ResultsOf the 784 patients, 39% self‐identified as immigrants. Median time of survey was 24 months after histological diagnosis. At baseline, immigrants had trends toward not meeting Canadian PA guidelines or being ever‐drinkers; patients from non‐Western countries were less likely to smoke (aORcurrent = 0.46, aORex‐smoker = 0.47, P = 0.02), drink alcohol (aORcurrent = 0.22, aORex‐drinker = 0.52, P < 0.001), or meet PA guidelines (aOR = 0.44, P = 0.006). Among immigrants, remote immigrants (migrated ≥40 years ago) were more likely to be consuming alcohol at diagnosis (aOR = 5.70, P < 0.001) compared to recent immigrants. Compared to nonimmigrants, immigrants were less likely to perceive smoking as harmful on QoL (aOR = 0.58, P = 0.008) and survival (aOR = 0.56, P = 0.002), and less likely to perceive that PA improved fatigue (aOR = 0.62, P = 0.04) and survival (aOR = 0.64, P = 0.08).ConclusionsImmigrants had different patterns of health behaviors than nonimmigrants. Immigrants were less likely to perceive continued smoking as harmful and were less likely to be aware of PA benefits. Culturally tailored counselling may be required for immigrants who smoke or are physically sedentary at diagnosis.
Social justice and remembering “the personal is political” in counselling and psychotherapy: So, what can therapists do?
Authors: Winter Laura Anne 
Published: March 2019

AbstractThis brief contribution argues for the importance of a social justice perspective in counselling and psychotherapy, particularly within the current international socio‐political context. Much has been said about social justice over recent years in the fields of psychology, psychotherapy and counselling. Professionals and academics have expressed some concerns about what it might actually mean, or how difficult it might be in practice to engage with this perspective. In this paper, the activist phrase “the personal is political” (Hanisch, 1970) is used to illustrate the way in which a social justice approach to counselling and psychotherapy does not need to be complicated, but rather a foregrounding of a particular understanding of well‐being and the people we work with. Following this, some concrete and straightforward suggestions for how therapists might begin to act on their social justice values are made.
SCAI expert consensus statement on operator and institutional requirements for PFO closure for secondary prevention of paradoxical embolic stroke
Authors: Horlick Eric , Kavinsky Clifford J. , Amin Zahid , Boudoulas Konstantinos Dean , Carroll John D. , Hijazi Ziyad M. , Leifer Dana , Lutsep Helmi L. , Rhodes John F. , Tobis Jonathan M. 
Published: March 2019

AbstractUntil recently, evidence to support Patent Foramen Ovale (PFO) closure for secondary prevention of recurrent stroke has been controversial. Publication of high‐quality evidence from randomized clinical trials and the subsequent FDA approval of two devices for percutaneous PFO closure is expected to increase the volume of PFO closure procedures not only in the United States but worldwide. As this technology is disseminated broadly to the public, ensuring the safe and efficacious performance of PFO closure is essential to mitigate risk and avoid unnecessary procedures. This document, prepared by a multi‐disciplinary writing group convened by the Society for Cardiovascular Angiography and Interventions and including representatives from the American Academy of Neurology, makes recommendations for institutional infrastructure and individual skills necessary to initiate and maintain an active PFO/stroke program, with emphasis on shared decision making and patient‐centered care.
Operando Spectroscopic Evidence of the Induced Effect of Residual Species in the Reaction Intermediates during CO2 Hydrogenation over Ruthenium Nanoparticles
Authors: Navarro‐Jaén Sara , Szego Anthony , Bobadilla Luis F. , Laguna Óscar H. , Romero‐Sarria Francisca , Centeno Miguel A. , Odriozola José A. 
Published: March 2019

AbstractIn this work, we present a highly active catalyst based on Ru nanoparticles dispersed on alumina, which showed an unexpected activity for CO2 methanation. This exceptional catalytic behavior was attributed to the presence of residual species that remained on the surface after synthesis. Furthermore, through Operando DRIFTS (diffuse reflectance infrared Fourier transform spectroscopy) measurements it was demonstrated that these remaining species provoked an induced effect on the nature of the surface intermediates spectroscopically observed, and consequently on their mechanistic role during the pathway of the CO2 hydrogenation to methane.
Digital color reconstructions of cultural heritage using color‐managed imaging and small‐aperture spectrophotometry
Authors: Berns Roy S. 
Published: March 2019

AbstractThere are many examples of cultural heritage having optical properties that have changed with the passage of time. Examples include the yellowing, darkening, and fading of paints and varnishes caused by light exposure and atmospheric pollution. When it is infeasible to treat an object, an image simulation can provide a view to the past, known as a color reconstruction. A technique is described that relies on a color‐managed image, spectral reflectance factor measurements of the object, an optical model of colorant mixing, an optical database of artist materials, spreadsheet software, and image editing software. Spectral calculations are used to create adjustment curves where segmented portions of an object's image are translated in color. This approach has been used to produce color reconstructions of paintings by Vincent van Gogh and Georges Seurat. This colorimetric translation methodology is described and an example shown for the Chicago version of Vincent van Gogh'sBedroom. The methodology is compared with pixel‐based processing.
Pharmacokinetic Properties of Ibuprofen (IBU) From the Fixed‐Dose Combination IBU/Caffeine (400/100 mg; FDC) in Comparison With 400 mg IBU as Acid or Lysinate Under Fasted and Fed Conditions—Data From 2 Single‐Center, Single‐Dose, Randomized Crossover Studies in Healthy Volunteers
Authors: Weiser Thomas , Schepers Cornelia , Mück Tobias , Lange Robert 
Published: March 2019

AbstractRapid onset of analgesic action is linked with rapid absorption of analgesics (high maximum concentration [Cmax] and short time to maximum concentration [tmax]). After overnight fasting, ibuprofen lysinate reaches higher peak plasma levels (Cmax) earlier than ibuprofen acid (tmax) with comparable exposure (area under the plasma concentration–time curve [AUC]); however, subjects usually take ibuprofen with or within a short time of a meal. Therefore, pharmacokinetic (PK) studies under fed conditions may better characterize properties under real‐life conditions. We investigated a new fixed‐dose combination (FDC) of ibuprofen acid 400 mg and caffeine 100 mg in 2 single‐dose, randomized, crossover PK studies in healthy subjects (both N = 36). The FDC was compared with ibuprofen 400 mg as acid and as lysinate after an overnight fast in Study 1, and with ibuprofen lysinate after a meal in Study 2. After fasting, results for ibuprofen in the FDC were comparable with those from ibuprofen acid alone. Caffeine did not affect the Cmax, tmax, and AUC. As expected, a higher Cmax and shorter tmax were observed with ibuprofen lysinates vs the FDC. Compared with administration after fasting, Cmax and tmax for ibuprofen lysinate administered postprandially were markedly different, while with FDC, these parameters were less sensitive to food intake. Taken after a meal, ibuprofen in the FDC reached tmax earlier than ibuprofen lysinate (median 1.25 vs 1.63 hours), and Cmax was approximately 13% higher, with comparable AUC, suggesting that the profile of ibuprofen was in favor of the FDC compared with ibuprofen lysinate. Thus, under real‐life conditions, ibuprofen lysinate had no PK advantage over the FDC. All preparations were well tolerated.
Nonvolatile kernel rootkit detection using cross‐view clean boot in cloud computing
Authors: Geetha Ramani R. , Suresh Kumar S. 
Published: March 2019

SummaryMalware attacks on kernel rootkits have become increasingly sophisticated and extremely difficult to detect; hence, they have a reign of power over the functionalities of the kernel. These kernel rootkits adopt stealth techniques to conceal the system processes, kernel modules, and other control structures, making it quite a challenge to detect their presence in the victim system. Many current efforts to detect the rootkits are based on known sources and are primarily system specific and hence are ineffective for newly mutating, hidden, and unknown rootkits. Therefore, in this paper, a kernel rootkit hidden file detection view (KRHFDV) system is proposed to detect such rootkits by identifying hidden files. This detection process uses a cross‐view clean‐boot‐based approach and defines a process monitoring framework that continuously maintains a list of active files and can detect both known and unknown rootkits with minimal performance overhead. KRHFDV overcomes the semantic gap by intercepting system call events of the tainted operating system in a nonintrusive manner and monitors the kernel to reconstruct a semantic‐level process information structure. The results from the extensive performance evaluation carried out with 64 rootkit samples in a cloud environment for both Linux and Windows kernels show that KRHFDV is able to identify file hiding behaviours of all samples in the least detection time.