bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Addition of Silica Nanoparticles to Type IV Dental Stone: Influence on the Diagonal Tensile Strength
Authors: Jafarabadi Sara Haji , Torab Ali , Rezaei Yashar , Radesh Parsa , Fahimi Mahsa , Hamedirad Fahimeh , Dizaj Solmaz Maleki 
Published: December 2024

Introduction:
Various methods have been studied to improve the properties of dental
stones; one of them is adding nanoparticles to dental stones. In this study, the effect of adding different
percentages of silica nanoparticles (0.5, 1, 2, and 5) on the diagonal tensile strength of dental
stone type IV was investigated.

Materials and Methods:
Silica nanoparticles with percentages of 0.5, 1, 2 and 5 physically were
mixed with dental stone type IV and then with distilled water according to the factory's instructions
(23 ml to 100 g at 23°C). The diagonal tensile strength was measured using a Universal Testing
Machine. In order to compare the diagonal tensile strength in different groups, ONE WAY
ANOVA test and SPSS.26 software were used. The significance level was considered 0.05.

Results:
The addition of silica nanoparticles to dental stone type IV had no effects on the diagonal
tensile strength of this material (P = 0.237).

Conclusion:
It can be concluded that adding silica nanoparticles does not negatively affect the diagonal
tensile strength, and all concentrations performed similarly. This suggests that any of these
concentrations can be used without concern for changes in tensile strength. However, further investigation
is needed to evaluate the impact on other properties.
A Clinical Study to evaluate the therapeutic effect of Akulyaabdadi Kashaya in Madhumeha (Type-II Diabetes Mellitus)
Authors: Pavitra Malik  
Published: December 2024

Introduction: In 2024 approximately 540 million adults (20-70 years) are living with diabetes as per data of IDF (international diabetes Federation). WHO states that diabetes will be 7th leading cause of death by 2030. Ayurveda says Madhumeha is a variety of Vataja Parmeha where the patient passes the urine with sweetness and astringency. The main symptoms involved are Prabhoota Mootrata (excessive urination) and Avila-Mootrata (non-transparency of urine). The major cause of disease is sedentary lifestyle and indulgence in Kapha-Medakar Aahara along with Divaswapana (day sleeping), avoidance of any form of exercise, hence indicating Santarpanjanya origin of disease. Methods: Akulyaabdadi Kashaya, the first Kashaya mentioned in Pramehahara Kashayas if Sahasrayoga is taken for single blind clinical study on 30 patients and the efficacy is established post 30-days of treatment. Results: During the study, it was found that signs and symptoms like polyuria, turbidity in urine, polyphagia, excessive thirst, burning sensation and numbness in feet, weakness, excessive sweating and lassitude were significantly reduced and Akulyaabdadi Kashaya, the trial drug was found highly significant at 0.1% level with p- value <0.001 to improve the FBS, PPBS, urine glucose (FUS & PPUS) and establishes it as a good treatment of Diabetes as a long term drug.
Effect of Panchavalkaladi Taila Yoni Pichu in the management of Paripluta Yoni Vyapad w.s.r. to Pelvic Inflammatory Disease - A Review Article
Authors: Astha jain  , Sucheta Ray  , Ekta Singh Parihar  , Priyanka Hajare  
Published: December 2024

Health is an important factor that contributes to human well-being and economic growth. Wisdom, art, strength and wealth are no use if health is lacking. Nidation of seed will grow only in satisfactory environment. Creation of good offspring highly depends on the woman’s reproductive health. Yoni Shuddhta is one among the major essential for a healthy offspring. Twenty types of Yoni Vyapad mentioned as the major cause of disease of the female reproductive tract. Paripluta Yoni Vyapad is one of them and in this, Vata and Pitta Dosha is considered the primary cause. It can be correlated with Pelvic Inflammatory Disease. PID is a disease of the upper genital tract. The main clinical features of Pelvic inflammatory disease are purulent vaginal discharge with foul smell, fever, pelvic pain and dyspareunia. It affects approximately 10% of women of reproductive age. Delayed management of PID may result in higher rates of miscarriage, chronic pelvic pain, STD, progressive organ damage and long-term reproductive disability due to its recurrence. There is a need to solve this emerging problem. In modern medicine antimicrobials, analgesics, NSAIDs are often prescribed in the treatment of Pelvic inflammatory disease which can be cause of many sides effect as headache, dizziness, drowsiness etc. So, the proper solution is made to find the safe and curative remedy in the form of Panchvalkaladi Tail Yoni Pichu for Paripluta Yoni Vyapad.
A critical review on Shwasahara Mahakashaya in relation to Tamaka Shwasa
Authors: Ankit Ashok Rathi  , Pradeep Shivram Pawar  
Published: December 2024

India is having rapid expansion, development and urbanization resulting into increased pollution levels leading to rise in respiratory illness. Bronchial asthma is one of the chronic respiratory diseases. Acharya Charaka has described five types of Shwasa Roga, Tamaka Shwasa is one of them. Charaka has elaborated etiopathogenesis, clinical features and treatment of Tamaka Shwasa. Shwasahara Mahakashaya is one of the unique composition of drugs explained by Acharya Charaka. It consists of ten Dravya’s, most of them tend to have Vata-Kaphaghna properties. Vitiated Vata- Kapha Dosha are responsible factors for pathogenesis of Tamaka Shwasa. The researches on pharmacological effect of this Dravya have shown Anti-inflammatory, Anti-histaminic, Anti-asthmatic properties.
MANAGEMENT ANALYSIS THE RELATIONSHIP MERCHANT MIDDLEMENT TO SUPPLIER AND CUSTOMER PEPPER IN MERANCANG ILIR VILLAGE, EAST BORNEO, INDONESIA
Authors: Daulika Putri 
Published: December 2024

The purpose of this study was to: 1) Describe the status and role of middlement in the trade and marketing of pepper, 2) Describes the purchasing system is being run, 3) Describes how to set the price, 4) Explaining SRM and CRM performed by middlement in maintaining a relationship with supplier and customer. This research used qualitative that have descriptive explanation characteristic. The researcher used participant-observation (participant observation), interviews and photos as the tools of collecting data. The determination participants and key informant for this research used snowball sampling techniques, with one participant and four key informants. This research used qualitative data that have descriptive explanation characteristic, are analyzed descriptively. The results of this study indicate that: 1) Status as a peppers collector in the pepper trading and marketing activities was the person who runs three roles at once, 2) Purchasing system was done by the collectors by collecting and looking for pepper from farmers (suppliers) to be purchased in accordance with market prices, and payment usually by giving cash advance prior to the harvest or by paid upon trading activities are taking place, 3) The system in pricing is applied and executed by an intermediary trader, namely the Mark-Up Pricing Method, amounting to IDR 2,000.00/kg pepper from the price given to customers, 4) The relationship management of supplier and customer who performed by collectors consist of: CRM activity (real relationship with customers and customer satisfaction), and SRM (commitment, communication, honestly, discussion, and sharing of information).
Estimating Patient and Family Costs and CO2 Emissions for Telehealth and In-Person Health Care Appointments in British Columbia, Canada: Geospatial Mixed Methods Study
Authors: Mainer-Pearson Graham , Stewart Kurtis , Williams Kim , Pawlovich John , Graham Scott , Riches Linda , Cressman Sonya , Ho Kendall 
Published: December 2024

Background
Patients inevitably incur some cost for accessing health care, even in universal systems such as Canada. The COVID-19 pandemic dramatically shifted health care delivery from in-person to telehealth services, also shifting the proportion of costs offset by patients and their families by reducing the need to travel to in-person appointments.

Objective
This study aimed to develop a method for estimating the costs patients and their families incur and CO2 emissions attributed to travel needed for emergency department (ED) visits, hospitalizations, and physician appointments.

Methods
We present a method to evaluate the costs associated with in-person and telehealth care appointments from the perspective of patients, their families, and the environment. We used ED locations, road distances, and duration of appointment to account for costs paid by patients (ie, lost productivity, informal caregiving, and out-of-pocket expenses) attributed to travel to receive medical care. Costs to the environment were evaluated by calculating the amount of CO2 emitted per medical visit. Using our costs calculated per visit, we apply our method to calculate total patient costs for a simulated population over 1 year.

Results
Our method estimates that patients in British Columbia pay up to $300 (2023 CAD, CAD $1=US $0.86) on average to attend an in-person ED visit, depending on where they live; $166 may be attributed to lost productivity, $83 to informal caregiving, and $50 to out-of-pocket expenses. These estimates are higher than most observed cost estimates. In addition, avoiding in-person care diverts up to 13 kg of CO2 per medical visit, depending on the distance and frequency of travel to appointments. This translates to up to $0.70 in carbon costs per visit, or cumulatively $44,120 per year in British Columbia, conventionally not included in patient cost estimates.

Conclusions
We present a novel method for estimating patient-incurred costs and CO2 emissions from accessing health care and apply it to estimate that every year, patients in British Columbia pay upwards of 30 million dollars to access health care services, primarily for medical travel. Our method adds to the economic evaluation literature by providing a more comprehensive and context-modifiable calculation of patient costs that will allow for more informed decision-making regarding health care services.
Análisis comparativo del descarte de restos faunísticos en la vertiente oriental de la Sierra de Velasco (La Rioja, Argentina) en la segunda mitad del primer milenio DC
Authors: Garate Enrique , Cahiza Pablo Andrés , García Gonzalo , Sabatini Gabriela Inés 
Published: December 2024

This paper discusses practices related to the consumption and disposal of faunal remains in village societies, groups and communities in the first millennium AD (Castro Barros, La Rioja, Argentina). It draws on an analysis of four zooarchaeological assemblages from El Chañarcito and Los Cardones de Aminga sites, where occupation dates back to the period between 660 and 900 AD. These sites were chosen because areas dedicated to the disposal of faunal remains have been identified at both. The zooarchaeological analysis corroborated differences in assemblages recovered from residential areas and those obtained from platforms or middens. Since disposal practices occur within specific cultural contexts where certain shared norms regarding order and cleanliness prevail, it also identified different ideas concerning the integration of platforms and middens into the public sphere. The results provide new evidence on waste management and how middens integrated with community life by transforming into heaps or platforms.
SOCIOPRAGMATICS ANALYSIS OF SYMPATHY AND EMPATHY EXPRESSIONS FOUND ON INSTAGRAM IN A VIDEO OF CHILDREN IN GAZA
Authors: Puspitasari Mawar , Siti Zuhriah Ariatmi  
Published: December 2024

The genocide committed by Israel in Gaza is still ongoing to this day. This action has received enormous attention from people from all over the world because it has claimed many victims ranging from children, adults, to the elderly. The purpose of this study is to describe the types of expressions of sympathy and empathy and to clarify the intention of sympathy and empathy expressions given by Instagram users to videos of children in Gaza.

E-ISSN: 2621-9158
P-ISSN:2356-0401

*Correspondence: mawarrrp05@gmail.com

Submitted: 23 November 2024
Approved: 5 December 2024
Published: 9 December 2024

Citation:
Puspitasari, M., & Ariatmi, S.Z. (2024). Sociopragmatics analysis of sympathy and empathy expressions found on instagram in a video of children in Gaza. Celtic: A Journal of Culture, English Language Teaching, Literature and Linguistics, 11(2), 306-321. Doi: 10.22219/celtic.v11i2. 37721

This study used a qualitative descriptive method. This study used observation and documentation methods to find the data. Research reveal that there are 2 types of sympathy, namely passive sympathy and active sympathy. This study also reveals that there are 3 types of empathy, namely cognitive empathy, emotional empathy, and compassionate empathy. As for the type of intention, 13 speech acts were found in this study, namely requesting, begging, proposing, vowing, thanking, apologizing, regretting, lamenting, blaming, praising, wishing, condoling, and criticizing. The findings of this study can be used to broaden understanding and make it easier for readers to distinguish expressions of sympathy and empathy.
System and Organization Controls (SOC) for Cybersecurity as a Nonaudit Service
Authors: Perols Rebecca R. , Murthy Uday S. 
Published: December 2024

SUMMARY
As cybersecurity risk and disclosure requirements increase, companies are looking to audit practitioners to provide System and Organization Controls (SOC) for Cybersecurity assurance services. Companies can choose to use the same firm as their financial statement auditor (joint provisioning) or a separate assurance provider. This article summarizes a study examining the effects of joint or separate provisioning of this service and cybersecurity incidents on investors’ perceptions of audit quality and investment decisions (Perols and Murthy 2021). The study finds that when the service is jointly provisioned, the negative signal of a subsequent cybersecurity incident can reverse investors’ positive perceptions of auditor competence, increase investors’ sensitivity to potential independence impairments, and result in lower perceptions of audit quality. Overall, the study finds that investors can be less willing to invest in a company when the service is jointly compared to separately provisioned. This article highlights implications for companies, practitioners, and regulators.
Using Blockchain, Non-Fungible Tokens, and Smart Contracts to Track and Report Greenhouse Gas Emissions
Authors: Jenkins J. Gregory , Negangard Eric M. , Sheldon Mark D. 
Published: December 2024

ABSTRACT
Global markets are moving toward requiring firms to track and report greenhouse gas emissions across their value chain. This includes self-generated emissions (i.e., Scope 1), emissions from power providers (i.e., Scope 2), and emissions from upstream suppliers and downstream parties (i.e., Scope 3). Yet, obtaining reliable emissions data is a complex task that often relies on cumbersome legacy processes and becomes especially challenging with upstream and downstream emissions. Using the Design Science Research Methodology, we propose and prototype (early-stage) a technological solution that uses blockchain, non-fungible tokens, and smart contracts to track and report greenhouse gas emissions across a firm’s value chain. The proposed model demonstrates how these tools can create a reliable classification and provenance of emissions that all value chain members can access for reporting purposes. Experts in the field evaluate the proposed model, find it technologically feasible, and call attention to some of its challenges.
JEL Classifications: C81; P28; Q51; Q55; Q56.
Gain of Function NOTCH3 Variants Cause Familial Partial Lipodystrophy Due to Activation of Senescence Pathways
Authors: Garg Abhimanyu , Xing Chao , Agarwal Anil K. , Westfall Aundrea K. , Tomchick Diana R. , Zhang Xunzhi , Xing Michelle , Brown Rebecca J. 
Published: December 2024

Despite elucidation of the molecular genetic basis of several lipodystrophy syndromes, molecular defects in some ultra-rare subtypes of familial lipodystrophies remain unidentified. We analyzed whole-exome sequencing (WES) data of four affected and two unaffected females from an undiagnosed autosomal dominant familial partial lipodystrophy (FPL) pedigree and identified only one novel heterozygous variant, p.Ala1603Tyr, in NOTCH3 meeting the filtering criteria. Further analysis of WES data of 222 patients with unexplained FPL identified two unrelated patients with FPL with novel heterozygous (p.Cys1600Tyr and p.Gln1552Pro) NOTCH3 variants. All variants were clustered in the heterodimerization domain of the negative regulatory region of NOTCH3. RNA sequencing and proteomics analysis of skin fibroblasts revealed significantly higher RNA and protein expression of NOTCH3 and activation of widespread senescence pathways in the patients with FPL versus control study participants. NOTCH3 is highly expressed in adipose tissue and plays many crucial roles in developmental patterning, cell fate decisions, regulation of cell survival, and proliferation. We conclude that gain-of-function missense variants in the negative regulatory region of NOTCH3 cause a novel subtype of FPL by activation of senescence pathways. This novel variety of FPL should be considered for patients without obesity but with early- or childhood-onset diabetes.

Article Highlights
Molecular genetic defects in some ultra-rare subtypes of familial partial lipodystrophies (FPLs) remain unidentified. We investigated whether novel gene variants explain FPL in some undiagnosed patients. We found novel heterozygous gain-of-function missense variants clustered in the heterodimerization domain of the negative regulatory region of NOTCH3 in three unrelated families with FPL. Our study suggests that gain-of-function missense variants in the heterodimerization domain of NOTCH3 cause a novel subtype of FPL by activation of senescence pathways.
Adipose Tissue Biology and Effect of Weight Loss in Women With Lipedema
Authors: Cifarelli Vincenza , Smith Gordon I. , Gonzalez-Nieves Silvia , Samovski Dmitri , Palacios Hector H. , Yoshino Jun , Stein Richard I. , Fuchs Anja , Wright Thomas F. , Klein Samuel 
Published: December 2024

Lipedema is a lipodystrophic disease that is typically characterized by a marked increase in lower-body subcutaneous adipose tissue that is purported to have increased inflammation and fibrosis, have impaired microvascular/lymphatic circulation, and be resistant to reduction by weight loss therapy. However, these outcomes have not been adequately studied. We evaluated body composition, insulin sensitivity, metabolic health, and adipose tissue biology in women with obesity and lipedema (Obese-LIP) before and after moderate (∼9%) diet-induced weight loss. At baseline, people with Obese-LIP had ∼23% greater leg fat mass, ∼11% lower android-to-gynoid ratio, and ∼48% greater insulin sensitivity (all P &lt; 0.05) than women matched on age, BMI, and whole-body adiposity. In Obese-LIP, macrophage content and expression of genes involved in inflammation and fibrosis were greater, whereas lymph/angiogenesis-related genes were lower in thigh than abdominal subcutaneous adipose tissue. Weight loss improved insulin sensitivity and decreased total fat mass, with similar relative reductions in abdominal and leg fat masses, but without changes in markers of inflammation and fibrosis. These results demonstrate that affected adipose tissue in women with lipedema is characterized by increased inflammation and fibrogenesis, and alterations in lymphatic and vascular biology. Moderate diet-induced weight loss improves metabolic function and decreases lower-body adipose tissue mass.

Article Highlights
We sought to increase our understanding of the pathophysiology of lipedema and the effects of weight loss. We examined whether there are differences in upper- and lower-body adipose tissue biology in lipedema and whether adipose tissue is affected by weight loss. Women with obesity and lipedema have decreased expression of genes related to lymphatic/vascular function and increased expression of genes related to fibrosis and inflammation in thigh compared with abdominal subcutaneous adipose tissue; weight loss increased insulin sensitivity and decreased leg fat but did not affect adipose tissue inflammation or fibrosis. Weight loss should be the first-line therapy for women with obesity and lipedema.
DEKORASI KERAJINAN GERABAH DI DESA PENAKAK KABUPATEN LOMBOK TIMUR
Authors: Putri Yuliana Khairi , Koriawan Gede Eka Harsana , Sudarmawan Agus 
Published: December 2024

Tujuan dari penelitian ini yaitu untuk mendeskripsikan bentuk, proses pembuatan dan nilai estetika yang terdapat dalam motif kerajinan gerabah di desa Penakak. Penelitian ini menggunakan jenis penelitian kulitatif dan dengan pendekatan deskriptif. Subjek dari penelitian ini yaitu pemilik galeri dan para pengrajin gerabah di galeri Yatni ArtShop desa Penakak Kabupaten Lombok Timur. Dan objek dari penelitian adalah hasil karya dekorasi kerajinan gerabah di desa Penakak Kabupaten Lombok Timur. Teknik pengumpulan data yang digunakan meliputi, observasi, wawancara, dokumentasi dan kepustakaan. Teknik analisis data menggunakan analisis domain dan analisis taksonomi. Hasil penelitian menunjukan: 1) Bentuk-bentuk dekorasi kerajinan gerabah. 2) Proses pembuatan dekorasi kerajinan gerabah. 3) Nilai estatika yang terkandung dalam motif dekorasi kerajinan gerabah. Kesimpulan dari penelitian yang dilakukan adalah dekorasi kerajinan gerabah di desa Penakak memiliki bermacam-macam bentuk dan motif, dimana proses pembuatan dekorasinya memerlukan gerabah yang setengah kering dan adapula yang sudah dibakar. Selain itu, dalam motif dekorasi gerabah di desa penakak memiliki nilai estetika yang dapat dilihat dari unsur-unsur seni rupa dan prinsip-prinsip seni rupa.

Kata Kunci: Dekorasi kerajinan gerabah, proses pembuatan, motif, estetika
LUKISAN KOLASE DARI SAMPAH PLASTIK MADE AGUS JANARDANA DI DESA BUNGKULAN,KECAMATAN SAWAN, KABUPATEN BULELENG, BALI
Authors: Setiawan Kadek Rizky , Ardana I Gusti Ngurah Sura , Koriawan Gede Eka Harsana 
Published: December 2024

Indonesia merupakan negara dengan memiliki kreativitas yang tinggi, salah satunya adalah lukisan kolase dari bahan sampah plastik. Penelitian Lukisan kolase Dari Sampah Plastik Made Agus Janardana Di Desa Bungkulan, Kecamatan Sawan, Kabupaten Buleleng, Bali bertujuan untuk memperoleh gambaran tentang (1) alat dan bahan yang digunakan dalam proses pembuatan lukisan wajah dari bahan sampah plastik, (2) proses pembuatan lukisan wajah dari bahan sampah plastik (3) mencari nilai estetika dalam lukisan kolase dari bahan sampah plastik didesa bungkulan, kecamatan sawan, buleleng, bali. Metode pengumpulan data yang dilakukan adalah menggunakan metode, observasi, wawancara, dokumentasi. Penulis menggunakan metode penelitiaan berjenis metode penelitian deskriptif kulitatif. Hasil penelitian ini adalah sebagai berikut: alat dan bahan yang digunakan dalam proses pembuatan lukisan kolase dari bahan sampah plastik ini antara lain gunting, pisau/cutter, laptop, aplikasi photoshop. Dan bahan yang digunakan damlam pembuatan lukisan kolase dari bahan sampah plastik ini adalah sampah plastik, lem fox, kertas, bingkai. Proses pembuatan lukisan kolase dari bahan sampah plastik ini adalah diawali dengann desain wajah menggunakan aplikasi photoshop di dalam laptop, lalu dilanjutkan dengan mencetak desain dengan dua rangkap cetakan yang dibutuhkan. Setelah itu cetakan yang pertama digunakan sebagai mal dan cetakan yang kedua di jadikan sebagai media. Mal dipotong sesuai warna. Lalu dilanjutjan dengan pemilihan sampah plastik yang cocok dengan mal dan langsung dipotong sesuai mal. Setelah itu sampah yang telah dipotong di tempel dengan cetakan desain yang dijadikan media. Begitu seterusnya sampai seluruh desain tertutupi oleh sampah plastik. Nilai estetika dalam lukisan kolase dari bahan sampah plastik ini antara lain dari unsur titik, garis, ruang tekstur, warna, dan gelap terang.

Kata kunci: kolase, sampah, plastik