bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-Cancerous Effect of Rutin Against HPV-C33A Cervical Cancer Cells via G0/G1 Cell Cycle Arrest and Apoptotic Induction
Authors: Khan Fahad , Pandey Pratibha , Upadhyay Tarun K. , Jafri Asif , Jha Niraj K. , Mishra Rashmi , Singh Vineeta 
Published: August 2019

Background:
Nowadays, the potential therapeutic role of various bioflavonoids including
Curcumin, Luteolin and Resveratrol has currently been well-documented in a vast range of fatal complications
including synaptic failure and cancers. These bioflavonoids are widely being implemented
for the treatment of various cancers as they possess anti-cancerous, anti-oxidant and anti-inflammatory
properties. Moreover, they are also used as a better alternative to conventional therapies since; these
are non-toxic to cells and having no or least side effects. Notably, the pertinent therapeutic role of Rutin
in cervical cancer is still unsettled however, its anti-cancerous role has already been reported in
other cancers including prostate and colon cancer. Rutin (Vitamin P or Rutoside) is a polyphenolics
flavonoid exhibiting multi-beneficial roles against several carcinomas.

Objective:
Despite the evidence for its several biological activities, the anticancer effects of Rutin on
human cervical cancer (C33A) cells remain to be explored. In this study, the anticancer potential of
Rutin was investigated by employing the key biomarkers such as nuclear condensation reactive oxygen
species (ROS), apoptosis, and changes in mitochondrial membrane potential (MMP).

Results:
Our findings showed that Rutin treatment reduced the cell viability, induced significant increase
in ROS production and nuclear condensation in dose-dependent manner. Moreover, Rutin provoked
apoptosis by inducing decrease in MMP and activation of caspase-3. Cell cycle analysis further
confirmed the efficacy of Rutin by showing cell cycle arrest at G0/G1 phase.

Conclusion:
Thus, our study is envisaged to open up interests for elucidating Rutin as an anticancerous
agent against cervical cancer.
Vanadium Oxide Nanofibers: Synthesis and Research on Functional Properties
Authors: Berezina O. Ya. , Markova N.P. , Kolobova E.N. , Pergament A.L. , Yakovleva D.S. , Zlomanov V.P. , Krivoshchapov N.V. 
Published: August 2019

Aim:Vanadium oxide nanofibers have been manufactured by the sol–gel electrospinning method followed by the thermal treatment in air and argon.Materials and Methods:The samples are characterized by optical, laser confocal and scanning electron microscopy, energy-dispersive X-ray elemental analysis, X-ray diffraction, cyclic voltammetry, and electrical conductivity measurements.Results:The obtained VO2 nanofibers demonstrate the semiconductor-to-metal phase transition. Also, the vanadium pentoxide nanofibers are examined as electrode materials for rechargeable Li-ion batteries.
Patient Commitment to Health (PACT-Health) in the Heart Failure Population: A Focus Group Study of an Active Communication Framework for Patient-Centered Health Behavior Change
Authors: Meeker Daniella , Goldberg Jordan , Kim Katherine K , Peneva Desi , Campos Hugo De Oliveira , Maclean Ross , Selby Van , Doctor Jason N 
Published: August 2019

Background
Over 6 million Americans have heart failure, and 1 in 8 deaths included heart failure as a contributing cause in 2016. Lifestyle changes and adherence to diet and exercise regimens are important in limiting disease progression. Health coaching and public commitment are two interactive communication strategies that may improve self-management of heart failure.

Objective
This study aimed to conduct patient focus groups to gain insight into how best to implement health coaching and public commitment strategies within the heart failure population.

Methods
Focus groups were conducted in two locations. We studied 2 patients in Oakland, California, and 5 patients in Los Angeles, California. Patients were referred by local cardiologists and had to have a diagnosis of chronic heart failure. We used a semistructured interview tool to explore several patient-centered themes including medication adherence, exercise habits, dietary habits, goals, accountability, and rewards. We coded focus group data using the a priori coding criteria for these domains.

Results
Medication adherence barriers included regimen complexity, forgetfulness, and difficulty coping with side effects. Participants reported that they receive little instruction from care providers on appropriate exercise and dietary habits. They also reported personal and social obstacles to achieving these objectives. Participants were in favor of structured goal setting, use of online social networks, and financial rewards as a means of promoting health lifestyles. Peers were viewed as better motivating agents than family members.

Conclusions
An active communication framework involving dissemination of diet- and exercise-related health information, structured goal setting, peer accountability, and financial rewards appears promising in the management of heart failure.
Lista de especies, endemismo y conservación de los mamíferos de Costa Rica
Authors: Herrera Bernal Rodríguez , Miranda Federico Chinchilla , Collado Laura J. May 
Published: August 2019

Abstract: The geographical position of Costa Rica has historically played an important role in the composition and diversity of our mammalian fauna, consisting of species originating both in the Neartic and Neotropical regions. Based on published data, new descriptions and reports, we here present an updated list of all terrestrial and aquatic Costa Rican mammals. We summarize available information on their status, and present our concerns regarding those species with populations under alarming conditions. The mammalian fauna of Costa Rica is mainly Neotropical. A total of 238 species, grouped in 140 genera and 44 families, were documented. The order Chiroptera is the most diverse, followed by Rodentia, Cetacea, and Carnivora. About 7% of the species are endemic to Costa Rica (or Costa Rica-Nicaragua, Costa Rica-Panamá). Unfortunately, despite of all the efforts to protect our fauna and flora, threat to Costa Rican mammals is increasing, and a number of species have gone, and are going extinct. As in most other areas, habitat loss, both in terrestrial and coastal ecosystems, poses the greatest threat to mammalian diversity of Costa Rica. Other factors, such as poaching, inappropriate gear used in fisheries, and other human exploitation are also threatening mammal populations in Costa Rica. Future conservation efforts should focus on more detailed conservation and management strategies, particularly of large mammals (e.g. monkeys, felids).Key words: Costa Rica, species richness, mammals, conservation, endemism.
Vertebrados post-glaciales en un residuario fósil de <i>Tyto alba scopoli</i> (Aves: <i>Tytonidae</i>) en el occidente de
Authors: Vázquez Osvaldo Jiménez , Condis Marjorie M. , Cancio Elvis García 
Published: August 2019

Resumen: Se estudió un depósito fosilífero cavernario localizado en el occidente de Cuba y constituido por regurgitaciones de estrígidas. Este depósito fue el resultado de la actividad trófica de la lechuza (Tyto alba), la cual depredó anfibios, reptiles, aves y mamíferos, y fue fechado entre el Holoceno Temprano a Medio (C 14 -7 864 ± 96 años AP). Este estudio mostró una panorámica de la fauna antigua procedente de paisajes terrestres con bosques húmedos en sabanas, con posterioridad a la culminación de la última fase árida del Pleistoceno-Holoceno. Palabras clave: Paleontología; Tafonomía, Tyto alba, Regurgitaciones, Pleistoceno-Holoceno, Cuba. Abstract: A cave fossiliferous deposit formed for barn owl pellets in western part of Cuba are studied. This were results barn owl (Tyto alba) predation on amphibians, reptiles, birds and mammals and are dated in Early-Middle Holocene (C 14 -7 864 ± 96 years BP). These studies show an ancient faunal picture from terrestrial landscapes with moist forest in savannas after last Pleistocene-Holocene arid period. Key words: Paleontology, Tafonomy, Tyto alba, ,Regurgitations, Pleistocene-Holocene.
Mamíferos del bosque mesófilo de montaña del Municipio de San Felipe Usila, Tuxtepec, Oaxaca, México
Authors: Pérez-Lustre Martín , Díaz Rusby Guadalupe Contreras , Moreno Antonio Santos 
Published: August 2019

Resumen: Se realizó el inventario de la mastofauna en el Bosque Mesófilo de Montaña del Municipio de San Felipe Usila en el Distrito de Tuxtepec, Oaxaca, durante cinco periodos mensuales de julio a noviembre de 2005. Se registraron representantes de cinco ordenes, 11 familias, 22 géneros y 23 especies, de las cuales una es endémica, siete están incluidas en alguna categoría de riesgo de acuerdo a normas nacionales e internacionales y cuatro son consideradas indicadoras de buena calidad ambiental, que incluyen tres quirópteros y un carnívoro. Las especies más abundantes fueron el murciélago Sturnira ludovici y el roedor Peromyscus mexicanus. Palabras clave: Riqueza de especies, Bosque Mesófilo de Montaña, San Felipe Usila, Oaxaca, México. Abstract: A mammal inventory of the cloud forest area of San Felipe Usila town, Tuxtepec, Oaxaca was carried out. The Santa Cruz Tepetotutla and San Antonio del Barrio communities were sampled between July and November 2005. We recorded five orders, 11 families, 22 genera, and 23 species, one species is endemic, seven are considered endangered according to national and international laws, and four are indicators of good quality of the environment, included three bats and one carnivore. The most abundant species was the bat Sturnira ludovici and the rodent Peromyscus mexicanus. Key words: Species richness, Cloud forest, San Felipe Usila, Oaxaca, Mexico.
Northern-most record of the collared anteater (<i>Tamandua mexicana</i>) from the Pacific slope of Mexico
Authors: Burton Andrew M. , González Gerardo Ceballos 
Published: August 2019

Abstract: We report the first record for the collared anteater (Tamandua mexicana) from Colima, Mexico. This record represents a northern range expansion along the Pacific slope. The presence of T. mexicana in Colima can be explained by two different mutually exlcusive hypotheses; the first is that the species has been historically present and was not recorded earlier; the second one is that the collared anteater has just recently dispersed into the state. We strongly support the second hypothesis. Key words: Tamandua mexicana, Colima, record. Palabras clave: Tamandua mexicana, Colima, nuevo registro.
Comunidad de pequeños roedores en una milpa tradicional del centro de Yucatán, México.
Authors: Cimé-Pool José , Hernández-Betancourt Silvia F. , Chablé-Santos Juan 
Published: August 2019

Abstract. A small rodent species was studied in two agroecosystems from Yucatan: (1) a traditional cornfield and (2) an induced grassland. A total of 87 individuals of six species in two families (Heteromyidae y Cricetidae) were captured rendering an effort of 2,544 nights/trap. Heteromys gaumeri and Peromyscus yucatanicus were the most abundant species with 57.5% and 17.2% of total captures, respectively. Highest captures were recorded in the traditional cornfield and the highest species richness was obtained in the grassland. No significant differences in diversity were found between sites (p > 0.05). It seems that the cornfield plays an important role on both the diversity and population dynamics of small rodents because it presents the highest values in captures, density, recruitment, and in reproductive individuals. This may be related to a greater variety of cultivated plant species in this agroecosystem. Key words: Small mammals, rodents, Cornfield, Grassland, Yucatan, Mexico. Palabras clave: Pequeños mamíferos, roedores, milpa, pastizal, Yucatán, México.
Madrigueras de <i>Liomys pictus</i> en dos selvas tropicales del Pacífico mexicano.
Authors: Domínguez-Castellanos Yolanda , Meza Beatriz Hernandez , D. Angeles Mendoza , González Gerardo Ceballos 
Published: August 2019

Resumen: Se determinó la estructura y el contenido de las madrigueras de Liomys pictus por tipo de vegetación y temporada del año, en dos selvas tropicales del Pacífico Mexicano. Se encontraron 24 madrigueras: en la selva baja la mayoría son complejas, mientras que en la selva mediana son lineales, por consiguiente y de acuerdo a la clasificación de las madrigueras, en selva baja se presentaron madrigueras múltiples y en selva mediana madrigueras simples. De acuerdo al contenido, las de selva baja tienen en promedio una mayor cantidad de materiales en comparación a las de selva mediana. Se catalogaron un total de 248 especies de plantas de estas 50 se comparten en ambos sitios, del total de las especies se llegaron a identificar sólo 77. Las familias más representativas fueron Leguminoseae, Euphorbiaceae y Convolvulaceae. La estructura de las madrigueras no esta determinada por la temporalidad, sin embargo el contenido esta determinado con la cantidad de material almacenado aunque la producción de semillas esta definido por el patrón de fructificación que esta dado a lo largo del año.Palabras clave: Madrigueras, estructura, contenido, Liomys pictus, Jalisco, México.Abstract: We determined the structure and contents of burrows of Liomys pictus by vegetation type and season in two tropical forests of the Mexican Pacific. 24 burrows were found in the tropical dry forest and most complex, in the semi deciduous forest is linear, and therefore according to the classification of the burrows in the tropical dry forest are more numerous and simple in the semi deciduous forest. According to the content, of the tropical dry forest have on average a greater amount of material compared to the semi deciduous forest. Were categorized a total of 248 plant species of these 50 sites are shared in both the total number of species is to determine 77. The most representative families were Leguminoseae, Euphorbiaceae and Convulvolaceae. The structure of the burrows is not affected by the timing, but the content is determined with the amount of stored material but seed production is defined by the pattern of fruit that is given throughout the year.Key words: Burrows, structure, food hoarding, Liomys pictus, Jalisco, Mexico.
PERANCANGAN KUESIONER AGRESIVITAS MAHASISWA BERBASIS APLIKASI WONDERSHARE QUIZCREATOR DALAM PEMBELAJARAN KALKULUS DI INSTITUT TEKNOLOGI DAN BISNIS STIKOM BALI
Authors: Sugiharni Gusti Ayu Dessy 
Published: August 2019

Pengembangan kuesioner agresivitas mahasiswa ini merupakan penelitian yang dilaksanakan pada pembelajaran Kalkulus di Institut Teknologi dan Bisnis STIKOM Bali. Alasan penelitian ini dilaksanakan di Institut Teknologi dan Bisnis STIKOM Bali karena mempertimbangkan hasil observasi awal yaitu: tutorial dan media pembelajaran berbasis komputer yang pernah digunakan dalam pembelajaran kalkulus memang telah mampu menarik minat belajar mahasiswa. Bersamaan dengan aktifnya mahasiswa dalam mengikuti pembelajaran juga menunjukkan sikap agresif yang muncul dan sangat berpengaruh terhadap suasana belajar dikelas. Berkaitan dengan hal tersebut maka dirasa perlu mengadakan penelitian yang berhubungan dengan pengukuran tingkat agresivitas mahasiswa. Penelitian yang berhubungan dengan pengukuran tingkat agresivitas mahasiswa tentunya memerlukan sebuah kuesioner yang tepat. Maka dari itu perancangan kuesioner agresivitas perlu dilakukan untuk mendapatkan kuesioner agresivitas yang tepat. Tujuan dari penelitian ini adalah mendeskripsikan rancangan pembuatan kuesioner agresivitas yang akan digunakan untuk mengukur tingkat agresivitas mahasiswa STIKOM Bali dalam mengikuti pembelajaran Kalkulus. Penelitian ini merupakan jenis penelitian pengembangan dengan menggunakan desain pengembangan model 4-D, yang hanya berfokus sampai di tahap perancangan (design). Kuesioner agresivitas pada penelitian ini dikembangkan sesuai dengan analisis kebutuhan awal, analisis kepustakaan terhadap Buku Petunjuk Kuesioner dan Buku Psikolog Pendidikan, analisis kerangka konseptual dari aspek-aspek agresivitas. Perancangan kuesioner agresivitas disusun sesuai dengan konten acuan patokan skala likert dengan lima alternatif jawaban (Selalu, Sering, Kadang-kadang, Jarang, Tidak Pernah). Visualisasi rancangan kuesioner ini ditunjukkan dengan memanfaatkan aplikasi Wondershare QuizCreator.Kata kunci: Kuesioner, Agresivitas, Kalkulus, Wondershare QuizCreator.
PENGEMBANGAN SOAL TEST DIGITAL MATAKULIAH ASESMEN DAN EVALUASI MENGGUNAKAN APLIKASI WONDERSHARE
Authors: Adiarta Agus , Divayana Dewa Gede Hendra 
Published: August 2019

Penelitian ini mempunyai tujuan utama untuk memperkenalkan langkah-langkah membuat soal test berformat digital berbantuan aplikasi gratisan yang bernama wondershare. Hal ini menjadi penting untuk diketahui karena saat ini masih banyak pendidik yang belum mampu membuat sendiri soal test berformat digital yang valid, praktis, dan variatif. Pendekatan yang digunakan dalam penelitian adalah pengembangan. Metode yang digunakan dalam penelitian ini adalah Research & Development, dengan model Borg & Gall dengan 10 tahapan pengembangan, diantaranya: penelitian dan pengumpulan data lapangan, merencanakan penelitian, pengembangan desain, uji coba awal, revisi hasil uji coba awal, uji coba lapangan, revisi hasi uji coba lapangan, uji coba pemakaian, revisi produk akhir, serta desiminasi dan implementasi produk akhir. Fokus tahapan pengembangan pada penelitian ini adalah pada tahapan penelitian dan pengumpulan data lapangan, perencanaan penelitian, pengembangan desain, dan uji coba awal. Alat yang digunakan dalam pengumpulan data berupa kuesioner. Responden yang dilibatkan dalam uji coba awal sebanyak 10 orang. Teknik yang digunakan untuk menganalisis hasil penelitian adalah teknik deskriptif kuantitatif dengan membandingkan persentase efektivitas hasil uji cob awal dengan tabel efektivitas yang mengacu skala lima. Hasil penelitian ini menunjukkan adanya 9 model soal test digital variatif yang dapat dibuat menggunakan aplikasi wondershare khususnya untuk matakuliah Asesmen dan Evaluasi dengan tingkat efektivitas sebesar 88,4% sehingga termasuk kategori baik. Kata kunci: Soal Test, Digital, Asesmen dan Evaluasi, Wondershare
DUKUNGAN SOSIAL KELUARGA BAGI ORANG DENGAN DISABILITAS SENSORIK
Authors: Saputri Anisza Eva , Raharjo Santoso Tri , Apsari Nurliana Cipta 
Published: August 2019

Penelitian ini menggambarkan jenis-jenis dukungan sosial yang diberikan bagi orang dengan disabilitas sensorik (ODDs). Berbagai bentuk dukungan sosial bagi ODDs dapat membantu dan memperkuat keberfungsian sosial mereka. Keluarga merupakan lingkungan sosial pertama dan utama dalam mendukung keberfungsian sosial ODDs. Pekerja sosial memiliki mandate yang berperan dalam membantu kelompok rentan, termasuk ODDs dengan cara mengoptimalisasi berbagai sumber baik pada diri mereka, maupun lingkungan sosial. Pendekatan kualitatif dengan studi literature merupakan metode utama untuk menggambarkan secara konseptual mengenai kajian dukunag sosial keluarga bagi orang dengan disabilitas, khususnya disabilitas sensorik. This study describes the types of social support provided for people with sensory disabilities (ODDs). Various forms of social support for ODDs can help and strengthen their social functioning. Family is the first and foremost social environment in supporting the social functioning of ODDs. Social workers have a mandate that plays a role in helping vulnerable groups, including ODDs, by optimizing various sources both for themselves and the social environment. A qualitative approach with literature studies is the main method for conceptually describing the study of family social support for people with disabilities, especially sensory disabilities.
PEMBERDAYAAN MASYARAKAT DI DESA POTA WANGKA LABUAN BAJO MELALUI PROGRAM PEDULI LINGKUNGAN ( SEKOLAH LINGKUNGAN) DENGAN METODE PARTISIPATORY LEARNING AND ACTION
Authors: Rachim Hadiyanto Abdul , Ginting Philia Anindita 
Published: August 2019

Kegiatan pemberdayaan masyarakat ini bertujuan untuk meningkatkan kepedulian masyarakat di Desa Pota Wangka Labuan Bajo khususnya di bidang lingkungan melalui kegiatan YouCan Empower. YouCan Empower merupakan salah satu program kepemudaan dalam bidang pemberdayaan masyarkat dengan memberikan kontribusi nyata dan positif kepada masyarakat. Berdasarkan Hasil dan Pembahasan dari kegiatan yang telah terlaksana, Desa Pota Wangka memerlukan perhatian scara khusus dalam penanganan sampah rumah tangga, sampah organic, dan sampah plastik. Kegiatan pemberdayaan dilakukan selama tiga hari yang terbagi kedalam empat bidang yakni ekonomi, lingkungan, kesehatan , dan pendidikan. Sebagai upaya menumbuhkan kepedulian masyarakat dan kesadaran dalam pengelolaan sampah, dilaksanakan program peduli lingkungan dengan metode PLA ( Partisipatory Learning Action ) .Adapun kendala yang dialami yakni kurangnya akses transportasi dan fasilitas yang memadai pengelolaan sampah serta usaha mempertahankan kebiasaan mengelolah sampah yang sesuai. This community empowerment activity aims to increase Pota Wangka, Labuan Bajo villagers awareness, especially in environmental field through YouCan Empower activities. YouCan Empower is one of the youth programs in the field of community empowerment by doing a real and positive contribution to the community. Based on the results and discussion form the activities that had been carried out, Pota Wangka Village needs attention in handling household waste, organic waste, and plastic waste. The empowerment activities had carried out for three days which are divided into four domains :ecomonomics, environtment, health , and education. In effort to increase the villagers awareness in waste management, we did environtmental care programs with the PLA method ( Participatory Learning Action ). Some obstacles experienced were the lack of access to transportation and adequate facilities for waste management and efforts to maintain the habit of managing waste.
Estudio exploratorio de la microbiota edáfica en el Centro de Investigación y Educación Ambiental La Tribuna, Neiva-Huila
Authors: Echeverry Hernández Sonia , Méndez Puentes Carlos Alberto 
Published: August 2019

En general, los ecosistemas de bosque seco tropical no han sido suficientemente estudiados en comparación con otras zonas de vida, de allí se deriva la importancia de realizar este estudio en el Centro de Investigación y Educación Ambiental La Tribuna, asentamiento antiguo de explotación petrolera, con el objeto de establecer las posibles diferencias significativas entre poblaciones microbianas de algunos grupos funcionales del ciclo del carbono y del nitrógeno, heterótrofas totales y hongos por parcela y períodos pluviométricos. Las diferencias significativas observadas en este estudio se presentaron entre las poblaciones de amilolíticos y fijadores de nitrógeno como consecuencia de la temporada de lluvias o de la temporada seca; en las diferentes parcelas, los bacilos grampositivos esporulados fueron los microorganismos más abundantes presentando frecuencias de aparición entre común y muy común.