bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theorising Relationships and Sex Education (rse) as a Children’s Rights Issue Using A Foucauldian Lens
Authors: Heah Rachel 
Published: October 2024

Abstract
This article seeks to analyse the problems with provision of Relationships and Sex Education (rse) in English schools using a Foucauldian perspective. Through this analysis, I demonstrate that the rse curriculum is used as a tool for “governing” or controlling children’s exercise of their sexuality to ensure conformity with norms, behaviours and attitudes that adults perceive children should ascribe to. However, adults tend to deny children’s developing agency and their autonomy to make decisions in relation to their sexual lives. This ignores the realities of children’s lives, in which they are exposed to sexual knowledge and information through their interactions with others, or via the internet. Using Foucault’s conceptualisation of bio-power, I argue for shifting some of the power around rse discourses from adults to children themselves, through a children’s rights-based approach. This approach to rse will ensure that the curriculum is adequate, appropriate and effective for children.
From Grievances to Growth
Authors: Shah Mehdi , Turi Abdullah 
Published: October 2024

Abstract
Past animosities and complex geopolitics make the Israel-Palestine conflict complex and require a multifaceted approach. As modernization theory fails to address such conflicts, we combine post-colonial theory, identity politics, critical geopolitics, with modernization theory to provide a more complete picture. A comprehensive strategy for building a strong and united Palestinian society is presented in this paper, which emphasizes democratic changes, military power rebalancing, international law, and economic independence. Education and technological progress drive societal growth, so strong governance systems are essential for political stability. We demonstrate how these methods work and what are their drawbacks by analyzing real-life examples of how social, economic, and political factors affect conflict. In the study, governments, civil society, and international organizations are a key focus for finding a long-term solution. This extensive research on conflict resolution and growth expands the conversation and offers lessons that can be applied to various conflict situations.
Text-Fabric Dataset of the Samaritan Pentateuch
Authors: Naaijer Martijn , Højgaard Christian Canu , Schorch Stefan , Ehrensvärd Martin 
Published: October 2024

Abstract
In this article, the authors present a dataset of the text of the Samaritan Pentateuch with word-level linguistic annotations. The Samaritan Pentateuch is an important early witness of the Pentateuch or Torah. This dataset is based on a transcription generally taken from manuscript Dublin, Chester Beatty Library 751 (Genesis 1:1–Deuteronomy 32:36) and supplemented from manuscript Nablus (Kiryat Luza), Samaritan Synagogue, Garizim 1, where the former manuscript has not preserved the text (Deuteronomy 32:36b–34:10). The dataset is a Text-Fabric dataset. Text-Fabric is a Python package for processing annotated text corpora, which means that the dataset comes with an app, where the text can be inspected and queried using the annotations. It is also easy to perform textual and linguistic research using Python scripts and to make comparisons with other relevant textual datasets with the same annotation conventions.
The Principle of Suspension (bādha) in Early Mīmāṃsā: the Case of prāpta- and aprāptabādha
Authors: Ferrante Marco , Freschi Elisa 
Published: October 2024

Abstract
This article examines the notion of bādha or ‘suspension’, one of the primary hermeneutical devices the Mīmāṃsā school of Sanskrit philosophy implemented to avoid seeming clashes between different commands of the Veda. Through bādha, a Vedic injunction can temporarily be suspended to allow for the unchallenged application of another. In all other cases, the first command remains valid, and its authority is therefore not undermined. This essay analyses the history of the device within early Mīmāṃsā, elaborates on how to decide which of two clashing commands should be suspended, and examines the crucial distinction between a suspension of something ‘obtained’ and that of something that is ‘not obtained yet’.
Towards an Intellectual History of Cakravartin Kingship
Authors: Shirley Bruno M. 
Published: October 2024

Abstract
Cakravartin kingship has long been treated as an ahistorical constant in histories of premodern Southern Asia. This paper argues for an intellectual history of cakravartinship, based not on its articulation in supposedly authoritative texts—particularly Buddhist suttas—but instead on what I call a “genealogy of practice,” traced primarily through the inscriptional record. Such a genealogy suggests that the mid-eleventh century served as a watershed moment for cakravartin claims: across the Indian Ocean, across “religious” boundaries, and across vernacular languages.
‘Turkmen’ Sultan, Armenian Deputy?
Authors: Leube Georg 
Published: October 2024

Abstract
This article reconstructs the positionality of an individual bearing the Armenian name Arewšah, as well as the Turkic name Khwushqadam, who supported the refoundation of an Armenian Christian monastery at Erkan in ca. 1430 CE. He is stated to have supported this refoundation in his capacity as local governor (nāʾib) serving the Muslim Aqquyunlu ruler qara ʿUthmān. Based on a detailed survey of the notes of possession contained in the unique manuscript that praises the patronage of Arewšah / Khwushqadam at Erkan, I suggest that he originally hailed from the area around the town of Hizan / Bitlis south of Lake Van, before assuming a governorship in Aqquyunlu Dersim. Although the name Arewšah is not attested in Aqquyunlu court historiography, I conclude with the suggestion that he could be identical to the Khwushqadam bīk b. ʿAbdalʿazīz who is mentioned among Aqquyunlu leaders between ca. 1435 and 1455 CE.
Development of a framework of the skills and attributes needed by mental health professionals to provide optimal clinical care to people experiencing complex psychosis: A Delphi consensus study
Authors: Grattan Sarah , Davies Kimberley , Weise Janelle , Burns Nicholas , Murray Robyn , Weldon Jennifer , Ellis Robin , Lappin Julia M 
Published: October 2024

Background: Complex psychosis is associated with high social and economic costs. The key skills and attributes needed by mental health professionals to provide optimal clinical care to people experiencing complex psychosis have not previously been defined. A framework detailing these skills and attributes is needed to support the identification of training needs for those working with this population. Methods: A modified online Delphi method was used to reach consensus on the skills and attributes essential for mental health professionals to deliver optimal clinical care to people experiencing complex psychosis. Participants were international healthcare professionals and academic researchers who self-identified as experts in complex psychosis. Participants were asked to rate their level of agreement with each item on a five-point Likert-type scale and to provide comments. Qualitative feedback was used to modify existing, or create new, items for subsequent rounds. Results: 64 responses were received across three Delphi rounds. 167 items reached consensus and were endorsed (132 in Round 1, 31 in Round 2 and 4 in Round 3). Median score range for endorsed items was 4.5/5, with 88.6% scoring 5/5. All 167 endorsed items were included in the framework, categorised into 14 overarching domains. Conclusion: Multiple skills and attributes were identified as being core components required in the delivery of optimal care by mental health professionals to people experiencing complex psychosis. The resulting framework provides a benchmark for training and skill development of mental health clinicians at both individual and team levels to optimise effective working with this high-needs population.
Predicting Drowsy Driver Break Taking During Long Drives
Authors: Gaspar John G. , Tefft Brian , Carney Cher , Horrey William J. 
Published: October 2024

Objective The current study investigated the factors that predict drowsy drivers’ decisions regarding whether to take breaks versus continue driving during long simulator drives. Background Driver drowsiness contributes to substantial numbers of motor vehicle crashes, injuries, and deaths. Previous research has shown that taking a nap and consuming caffeine can temporarily mitigate drowsiness and enable continued safe driving. Method Ninety drivers completed a 150-mile highway drive in a driving simulator after a day of partial sleep restriction. Drivers passed several simulated rest areas where they could take breaks. To replicate drivers’ motivation to reach their destination safely but also quickly, drivers were told that they would be paid more for completing the simulated drive faster but would forfeit their payment if they crashed. Results Break taking was predicted by drivers’ self-ratings of drowsiness and by the severity of lane departures. However, even at the highest levels of drowsiness, most drivers bypassed simulated rest areas without stopping. In comparing self-rated drowsiness to drowsiness measured by eye closures, drivers often under- and over-estimate their own level of drowsiness. Conclusion Drowsy drivers use their own self-assessed drowsiness when deciding whether to take breaks. These self-assessments are often incorrect, and even when drivers rate themselves as severely drowsy they are unlikely to stop to rest during long drives. Application The findings reveal the need for effective drowsy driving countermeasures to motivate drivers to stop to take breaks. Results underscore the need to educate and/or motivate drivers to respond sooner to warning signs of drowsiness.
Comparative analysis of negative pressure wound therapy (PICO) and standard dressing application after arterial vascular reconstructions
Authors: Kostiuk Valentyna , Fereydooni Soraya , Setia Ocean , Loh Sarah A , Strosberg David , Tonnessen Britt H , Ochoa Chaar Cassius Iyad , Aboian Edouard 
Published: October 2024

Introduction Surgical site infections following arterial reconstructions with femoral exposures are common and potentially preventable. Negative pressure wound therapy has emerged as a potential solution to minimize groin wound complications. Our study evaluates efficacy of a negative pressure therapy (PICO dressing) in reducing groin wound complications after vascular reconstructions. Methods A retrospective single center comparative analysis of vascular reconstructions involving common femoral artery dissection was performed between July 2021 and June 2023. Patients were divided into two groups: patients treated with PICO device and patients who received standard dressing (non-PICO). Patient demographics, comorbidities, vascular evaluation, and procedure indications were compared. Previous interventions, incision orientation and procedure types were noted. The wound complication categories were graded according to the Szilagyi classification: grade 1 (superficial infection/minor dehiscence), grade 2 (deep infection/major dehiscence), and grade 3 (artery or prosthetic involvement). Statistical significance level was determined at p < .05 for all analyses. Results A total of 217 groin dissections in 184 patients were analyzed with 132 and 85 groin dissections in the PICO and non-PICO groups, respectively. The baseline characteristics were similar between the groups in terms of age, sex, BMI, and procedure indications. Prior endovascular procedures and re-operative groin surgeries were more prevalent in the PICO group. The use of antibiotics post-operatively for groin wound complication was greater in the non-PICO group. The incidence of wound complications was higher in the non-PICO group (29.4% vs 10.6%, p < .001). Multivariate logistic regression analysis determined that PICO dressing as well as hybrid and endovascular index procedures were associated with lower risks of groin complications. Conclusion PICO dressing decreased the incidence of groin wound complications in patients undergoing open vascular reconstructions. This study highlights the value of adjunctive negative pressure therapy in reduction of wound complications after arterial reconstructions in the inguinal region.
Prehospital blood pressure lowering in patients with ischemic stroke: A systematic review and meta-analysis of randomized controlled trials
Authors: Yuan Xiang , Gan Qi , Zhang Yu , Wang Peng , Chong Weelic , Hai Yang , Fang Fang 
Published: October 2024

Background: Whether prehospital blood pressure control improves outcomes among patients with acute ischemic stroke is uncertain. This systematic review and meta-analysis aimed to evaluate the effect of prehospital blood pressure reduction treatment in patients with ischemic stroke. Methods: We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials for randomized controlled trials that compared prehospital blood pressure reduction treatment with usual treatment or no treatment in patients with stroke. The primary outcome was functional outcome, assessed with the distribution of modified Rankin Scale (mRS) at 90 days, while secondary outcome was mortality at 90 days. Results: Of 428 studies reviewed, three were appropriate for analysis, totaling 3878 patients. In patients with ischemic stroke, prehospital blood pressure reduction treatment was associated with higher mRS scores at 90 days (common odds ratio (OR) for worse mRS, OR: 1.27, 95% confidence interval (CI): 1.08–1.49) and increased risk of mortality at 90 days (OR: 1.28, 95% CI: 1.02–1.61) compared with the usual treatment. Conclusion: In patients with ischemic stroke, prehospital blood pressure reduction treatment was associated with a higher likelihood of poor functional outcome and an elevated risk of mortality.
A review of the use of CT pulmonary angiography in pregnant and postpartum women at an academic centre
Authors: Herbst Wilhelm , Bhoora Shastra , Moodley Halvani , Ranchod Ashesh , Westgarth-Taylor Tracy , Zamparini Jarrod 
Published: October 2024

Background Pulmonary embolism (PE) is a common cause of maternal death during pregnancy and the puerperium yet data on its prevalence in middle-income countries is lacking. Methods We examined the medical records and CTPA (computed tomography pulmonary angiography) images of 67 women in an obstetric high care unit during pregnancy and the puerperium. We aimed to determine the prevalence of PE in a high-risk obstetric population undergoing CTPA, assess associated clinical features in this cohort, and determine the prevalence of alternative CT findings. Results CTPA detected PE in 11 women (16.42%) and alternative CT findings in 46 (68.6%). Women with PE had a lower systolic blood pressure than those without PE ( P = 0.001). Multiple gestation, preterm rupture of membranes, and gestational diabetes were linked to higher PE prevalence. Conclusions This study, set in an upper middle-income country, demonstrated a higher CTPA yield for PE and alternative diagnoses than in international literature, emphasising context-specific assessments.
Comparing quality of life in traditional face-to-face visits with a hybrid approach of telemedicine with in-person follow-ups in recent users of advanced closed-loop systems: a randomized controlled clinical trial in patients with type 1 diabetes
Authors: Nattero-Chávez Lía , de La Calle Esther , Lecumberri-Pascual Edurne , Bayona Cebada Ane , Ruiz Gracia Teresa , Quintero Tobar Alejandra , Lorenzo Moñino Mar , Sánchez Rodríguez Cristina , Izquierdo Ana , Escobar-Morreale Héctor F. , Luque-Ramírez Manuel 
Published: October 2024

Background: Our objective was to assess the effect of a hybrid telemedicine approach, in conjunction with face-to-face follow-up, on the quality of life in recent users of an advanced hybrid closed-loop (AHCL) system. Methods: A 1-year open randomized (1:1) clinical trial (ClinicalTrials.gov ID NCT04900636). Participants with type 1 diabetes (T1D) recent users of an AHCL system (Minimed® 780G) for at least 2–6 months, and ⩾18 years old were eligible. The primary outcome was the change in quality of life measured by the Type 1 Diabetes Life (ViDa1) Questionnaire from baseline to 12 months of hybrid telemedicine plus face-to-face follow-up compared to standard clinical practice. Additionally, impacts on A1c levels, glucose metrics, advert events, and safety outcomes were assessed. Results: Between January and December 2021, 46 participants were randomly assigned in a 1:1 ratio to either the hybrid telemedicine group ( n = 23) or the control group ( n = 23); 45 participants completed the study, with only 1 from the control group withdrawing before visit 3. At baseline, mean age was 37 ± 15 years and A1c was 6.9 ± 0.5%. After 12 months, no statistically significant differences in ViDa1 scores between groups were observed. Despite reducing in-person visits in the hybrid follow-up arm, there were no increases in adverse events. Overall, A1c levels significantly decreased from 6.9 ± 0.5% at baseline to 6.7 ± 0.5% after 12 months ( P = 0.006) without differences between treatment arms, accompanied by reductions in glycemic variability and time below the target range. Conclusion: Our study suggests that there were no significant differences in ViDa1 scores between the two groups at the end of the follow-up. However, among adult patients with T1D who recently adopted an AHCL system, satisfactory glycemic control can be attained through a hybrid follow-up approach, reducing face-to-face visits, without increasing technical complications.
Shrinkage estimation of gene interaction networks in single-cell RNA sequencing data
Authors: Vo Duong H. T. , Thorne Thomas 
Published: October 2024

Abstract
Background
Gene interaction networks are graphs in which nodes represent genes and edges represent functional interactions between them. These interactions can be at multiple levels, for instance, gene regulation, protein-protein interaction, or metabolic pathways. To analyse gene interaction networks at a large scale, gene co-expression network analysis is often applied on high-throughput gene expression data such as RNA sequencing data. With the advance in sequencing technology, expression of genes can be measured in individual cells. Single-cell RNA sequencing (scRNAseq) provides insights of cellular development, differentiation and characteristics at the transcriptomic level. High sparsity and high-dimensional data structures pose challenges in scRNAseq data analysis.

Results
In this study, a sparse inverse covariance matrix estimation framework for scRNAseq data is developed to capture direct functional interactions between genes. Comparative analyses highlight high performance and fast computation of Stein-type shrinkage in high-dimensional data using simulated scRNAseq data. Data transformation approaches also show improvement in performance of shrinkage methods in non-Gaussian distributed data. Zero-inflated modelling of scRNAseq data based on a negative binomial distribution enhances shrinkage performance in zero-inflated data without interference on non zero-inflated count data.

Conclusion
The proposed framework broadens application of graphical model in scRNAseq analysis with flexibility in sparsity of count data resulting from dropout events, high performance, and fast computational time. Implementation of the framework is in a reproducible Snakemake workflow https://github.com/calathea24/ZINBGraphicalModel and R package ZINBStein https://github.com/calathea24/ZINBStein.
Bacterial community dynamics as a result of growth-yield trade-off and multispecies metabolic interactions toward understanding the gut biofilm niche
Authors: Valiei Amin , Dickson Andrew M. , Aminian-Dehkordi Javad , Mofrad Mohammad R. K. 
Published: October 2024

AbstractBacterial communities are ubiquitous, found in natural ecosystems, such as soil, and within living organisms, like the human microbiome. The dynamics of these communities in diverse environments depend on factors such as spatial features of the microbial niche, biochemical kinetics, and interactions among bacteria. Moreover, in many systems, bacterial communities are influenced by multiple physical mechanisms, such as mass transport and detachment forces. One example is gut mucosal communities, where dense, closely packed communities develop under the concurrent influence of nutrient transport from the lumen and fluid-mediated detachment of bacteria. In this study, we model a mucosal niche through a coupled agent-based and finite-volume modeling approach. This methodology enables us to model bacterial interactions affected by nutrient release from various sources while adjusting individual bacterial kinetics. We explored how the dispersion and abundance of bacteria are influenced by biochemical kinetics in different types of metabolic interactions, with a particular focus on the trade-off between growth rate and yield. Our findings demonstrate that in competitive scenarios, higher growth rates result in a larger share of the niche space. In contrast, growth yield plays a critical role in neutralism, commensalism, and mutualism interactions. When bacteria are introduced sequentially, they cause distinct spatiotemporal effects, such as deeper niche colonization in commensalism and mutualism scenarios driven by species intermixing effects, which are enhanced by high growth yields. Moreover, sub-ecosystem interactions dictate the dynamics of three-species communities, sometimes yielding unexpected outcomes. Competitive, fast-growing bacteria demonstrate robust colonization abilities, yet they face challenges in displacing established mutualistic systems. Bacteria that develop a cooperative relationship with existing species typically obtain niche residence, regardless of their growth rates, although higher growth yields significantly enhance their abundance. Our results underscore the importance of bacterial niche dynamics in shaping community properties and succession, highlighting a new approach to manipulating microbial systems.