bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bilingual young adults’ perceived influence of parents, grandparents, siblings, and friends on their Spanish and English proficiency: A qualitative analysis
Authors: Jasso Javier , Castilla-Earls Anny , Fulcher-Rood Katrina , Heredia Gabriela 
Published: November 2024

Aims and objectives/purpose: Qualitative studies on bilingual individuals’ perspectives can inform research by identifying community understanding of lived phenomena and aiding in theory building. The purpose of this study was to examine the perceived role of external factors in the family, school, and community on the Spanish and English proficiency of a group of Latine Spanish–English bilingual university students. Methodology: A qualitative content analysis was used to compare participants’ perspectives and establish the commonality of their experiences. Researcher triangulation was used to ensure rigor. A consolidated criteria for reporting qualitative research was used to ensure that the design, collection, and analysis were consistent with accepted qualitative research standards ( Tong et al., 2007 ). Data and analysis: Twenty-three bilingual university students in Houston, United States, rated their proficiency in Spanish and English using the Language Experience and Proficiency Questionnaire (LEAP-Q; Marian et al., 2007 ) and participated in a structured in-person interview regarding their perceptions of the influence of various external factors on their English and Spanish proficiency. Findings: Factors reported to contribute most to adults’ Spanish proficiency included home interactions with parents, family language policies that encouraged Spanish language use, and the need to communicate with grandparents. The most important factors for English proficiency were friends, siblings, and the school environment. These findings aligned with the self-reported ratings. Originality: This study is one of the few to qualitatively examine bilingual adults’ experiences and report on relevant factors during childhood to early adulthood. Significance: Bilingual experiences in the Houston context are documented here. Findings from this and future studies may be useful to estimate the impact of external factors on proficiency in adulthood, which has implications for conceptual frameworks for bilingual acquisition research.
Exploring cross-linguistic transfer of phonology, morphology, syntax, and orthography from Arabic (L1) to English (FL): An intervention study
Authors: Haddad-Najjar Laila , Abu-Rabia Salim 
Published: November 2024

Aim and Objectives: There is ample evidence available in correlational studies for cross-linguistic transfer from the first language (L1) to a second or a foreign language (L2/FL). Less extensive are the interventional studies in this area. The current study sought to determine which linguistic skills transfer from Arabic (L1) to English (EFL) after employing an intervention program in Arabic. Design/ methodology: Participants were sixty-nine Arabic-speaking ninth graders randomly assigned to an experimental group receiving an intervention program in Arabic and a control group not receiving an intervention. Pre-tests and post-tests tapping phonological, orthographic, morphological, and syntactic awareness in English and Arabic were administered to all participants. Data Analysis: A two-way analysis of variance (ANOVA) for repeated measures compared the pre-test and post-test results in English and Arabic within each group and between the groups. In addition, a linear regression model was used to examine the predictive effect of pre-test scores and the intervention program in Arabic on post-test performance in English. Findings/Conclusion: Findings revealed a within-language improvement in all Arabic skills after the intervention. As for the cross-linguistic transfer, significant differences favoring the intervention group were only demonstrated in phonological and morphological skills. No transfer was evident in orthographic or syntactic transfer. Originality: By employing an intervention program addressing four linguistic skills in Arabic concurrently, the present study revealed a robust transfer of phonological and morphological awareness from Arabic to English, whereas it showed no transfer of orthographic or syntactic awareness. Significance: Findings, on the one hand, lend support to the linguistic Interdependent Hypothesis by suggesting that some linguistic skills can interdependently transfer across distant languages. On the contrary, findings endorse the Script Dependent Hypothesis, by showing that some other linguistic skills are language-specific, thereby, impeding cross-linguistic transfer.
Implementing the Earned Income Tax Credit: Shall Governments Design an Employee or an Employer-Based System
Authors: Strawczynski Michel 
Published: November 2024

In this paper, I use a labor market equilibrium model and a social welfare analysis for comparing between an employee-based Earned Income Tax Credit (EITC) and an employer-based system. Since the labor supply of the low-wage workers is relatively rigid, firms enjoy market power that might be used in detriment of the policy-maker's goals when implementing an EITC. While the employee-based system avoids coordination among firms, and thus reduces their market power, an employer-based system allows for automatic take-up at the initial stage of the program’s implementation, which constitutes an advantage. These pros and cons in both systems shall be weighted one against the other; for that purpose, I run simulations using empirically plausible parameters taken from Israel, where an EITC has been implemented for a decade and a half. The simulations show that in terms of social welfare, the employee-based EITC tends to dominate the employer-based system. JEL Numbers– H21, H24, and I38.
Avoiding Aortic Valve Passage in Branched Arch Repair by Use of the Modified Balloon Nose Cone Technique
Authors: Kasprzak Piotr , Kuczmik Waclaw , Pfister Karin , Rohlffs Fiona 
Published: November 2024

Purpose: To demonstrate the Modified Balloon Nose Cone Technique to avoid passage of the aortic valve in endovascular branched arch repair. Technique: The technique is demonstrated in a 54-year-old patient after previous open repair of the ascending aorta and mechanical aortic valve replacement due to type A aortic dissection. The delivery system of a custom-made stent-graft with 3 inner branches was modified by subtotally sawing off its nose cone. Using a right transaxillary access, a sheath was introduced over a through-and-through (TAT) wire exiting the left groin and meeting the branched stent-graft in a rendezvous fashion. A balloon was used to bridge the gap between both sheaths. Passing the innominate artery, both sheaths were pushed into the ascending aorta to establish a loop configuration of the balloon until the correct landing zone was reached. The main body was deployed, and the supra-aortic target vessels were connected. After the procedure, the mechanical aortic valve showed unimpaired function. Conclusion: The Modified Balloon Nose Cone Technique broadens the technical armamentarium in endovascular aortic arch repair offering a feasible solution to overcome the need of aortic valve passage. Especially patients with mechanical aortic valve could benefit from this method. Clinical Impact To describe the feasibility and safety of the Modified Balloon Nose Cone Technique in a severely comorbid patient with residual Type A aortic dissection and history of ascending aortic repair and mechanical replacement of the aortic valve to broaden the technical armamentarium in endovascular aortic arch repair offering a feasible solution to overcome the need of aortic valve passage.
“You said burnout? Whew, chile!” A multigenerational collaborative autoethnography on the complexities of burnout and care among Black women researching substance use
Authors: Malone Natalie , Palomino Kaylee A , Verty Valerie PA , Goggins Mona KM , Jester Jasmine K , Miller-Roenigk Brittany , Wheeler Paris , Dogan-Dixon Jardin , Keeling Mekaila , McCleod Kendall A , McCray India , Sigola Zoe A , Atkinson Jovonna D , Hargons Candice N , Stevens-Watkins Danelle 
Published: November 2024

Background: Researchers and participants who are members of minoritized populations experience negative psychosocial and wellness outcomes like burnout. Burnout may manifest uniquely for Black women in academia conducting research with Black women participants navigating similar sociocultural contexts. Objectives: This article qualitatively interprets our experiences as 15 Black women scholar-practitioners at a midwestern university conducting community-engaged research. We discuss our experiences of care and burnout while working to reduce opioid use disparities among Black women community members as we simultaneously navigate multilevel challenges in academia. Design: We employ collaborative autoethnography, an autobiographical writing method, using a Black feminist framework and intersectionality methodology. Methods: We are 15 Black women researcher-subjects on the REFOCUS study—a mixed-methods National Institute on Health-funded project examining nonmedical prescription opioid misuse among Black Kentuckians. We examined a series of multigenerational sista circles and individual journal entries we completed to understand the multilevel power dynamics impacting our individual and collective work, burnout, and care. Results: Themes were: (1) “I see me in you”: Research with Black Women, (2) “Pervasive, cellular, and epigenetic”: Burnout Experiences; (3) “Taxing but rewarding”: The Price We Pay to See an Outcome, and (4) “Thank God for the collective”: Complexities of Caring Through the Process. Conclusion: We highlight the importance of continued efforts to address workload inequities among Black women in academia, particularly for those working to combat health disparities among Black women or within Black communities. We make recommendations for structural, institutional, and interpersonal steps to improve the support of Black women across career stages.
Women’s self-concept of and real knowledge about nutrition: A cross-sectional study
Authors: Pavicic Elena , Vincenz Annaletta , Bitterlich Norman , von Wolff Michael , Stute Petra 
Published: November 2024

Background: Lifestyle in Western countries has significantly changed during recent decades. These and other factors have increased the prevalence of overweight and obesity, leading to a higher risk of noncommunicable diseases such as cardiovascular disease and cancer. A balanced diet has been shown to predict better health, so several public healthcare strategies aim to encourage “healthy” food choices. Objectives: To assess self-concept of knowledge about nutrition compared to factual knowledge and knowledge implementation in daily life. Design: Cross-sectional cohort study with a total of 524 Swiss women recruited, of which 447 women met the inclusion criteria for the final analysis. Methods: Main outcome measure: a self-constructed questionnaire was used to evaluate subjective and objective knowledge about healthy nutrition and its practical application. Subgroup analyses utilized Fisher’s test for categorical and Mann–Whitney- U test for metric/ordinal. Results: Most participants sourced their nutritional information predominantly from nonexperts. While the majority believed they were well-educated about nutrition, this self-assessment was only partially accurate. The “nutrition pyramid” concept was widely recognized, and correct assignment of food items to dominant macronutrient components was generally accurate. However, understanding of food category ranking by optimal daily intake and composing a healthy diet was lacking. Higher education levels correlated with better objective nutrition knowledge ( p < 0.001), and normal-weight women were more likely than overweight/obese women to implement nutritional knowledge daily ( p = 0.021). Apart from body mass index other bio-psycho-social factors were observed. Conclusion: Recent insights show that although women perceive themselves as knowledgeable about nutrition, there are significant gaps in their objective understanding. Higher education levels improve nutritional knowledge, and normal-weight women apply this knowledge more effectively. Thus, providing accessible, high-quality expert information on nutrition is essential. Trial registration: The study has been approved by the Cantonal Ethics Committee (registration number: 2018-00358).
Early reperfusion in patients with acute retinal artery occlusion: A multicenter prospective study
Authors: Abdelmassih Youssef , Mauget-Faÿsse Martine , Seners Pierre , Milea Dan , Hallali Gabriel , Guillaume Jessica , Lecler Augustin , Vignal Catherine , Le Mer Yannick , Paques Michel , Bonnin Sophie , Obadia Michael 
Published: November 2024

Background: The visual outcome after central retinal artery occlusion (CRAO) is poor, but its relationship with early reperfusion (ER) is poorly known. We evaluated the incidence of ER in acute CRAO or branch retinal artery occlusion (BRAO), and its association with clinical outcome. Methods: In this prospective observational multicenter study, we included patients with acute CRAO or macula-involving BRAO presenting within 24 hours from symptom onset. ER was evaluated within 24 hours after the initial clinical evaluation using indocyanine green angiography (ICGA). The primary outcome was the best-corrected visual acuity (BCVA) at 1 month. Results: In all, 70 patients were enrolled, of whom 63 (90%) had CRAO. Median age was 71 years (interquartile range: 67–77), 63% were male, median time from symptom onset to presentation was 5.3 hours (interquartile range: 3.1–15.1), and 17% received intravenous fibrinolysis. ER was identified in 34 patients (49%), of whom 21 (30%) achieved complete reperfusion (100% filling of the 55° ICGA field). Patients with ER were less likely to have hypertension and diabetes mellitus ( p < 0.001 and p = 0.046, respectively). At the 1-month follow-up, BCVA was significantly better in ER patients (median BCVA 1.3 logMAR vs 1.7 logMAR, p = 0.001), with greater benefit with complete reperfusion ( p for trend < 0.001). ER was also associated with improved visual field and quality of life at the 1-month follow-up (both p < 0.05). Conclusion: ER occurred in almost 50% of the patients and was associated with improved visual outcomes and quality of life. Therapies that increase ER in CRAO will likely improve clinical outcomes. Clinical Trial Registration: This study was registered on ClinicalTrials.gov (identifier NCT03049514); https://classic.clinicaltrials.gov/ct2/show/NCT03049514
How tube feeding modes influence anxiety in patients with dysphagia after ischemic stroke: A propensity score-matched, longitudinal study
Authors: Zeng Hongji , Zhao Weijia , Zeng Jing , Wang Rui , Luo Hong , Wen Changming , Liu Yanbo , Li Dongjian , Zeng Xi 
Published: November 2024

Background: Although tube feeding modes have been shown to influence psychological status, the specific mechanism of action and differences between intermittent oro-esophageal tube feeding (IOE) and nasogastric tube feeding (NGT) have yet to be uncovered. This study explored the effect of IOE versus NGT on anxiety in patients with dysphagia after ischemic stroke. Methods: This longitudinal observational study included patients with dysphagia after ischemic stroke who were treated in the Department of Rehabilitation Medicine between February 2022 and June 2024. Questionnaires, scales, and medical records were used to collect data regarding anxiety symptoms, basic information, treatment details, and self-perception on the 1st and 10th day of hospitalization. Propensity Score Matching (PSM) was used to balance potential confounding factors and analyze the association between IOE versus NGT and anxiety symptoms. Path analysis was conducted to explore the specific mechanisms of action. Results: Totally, 2459 participants (55.51% IOE users) were recruited. The IOE users had significantly lower moderate-to-severe anxiety rates than the NGT users (25.88% and 44.42%, p < 0.001). PSM analysis revealed an 8.56% difference in moderate-to-severe anxiety rates between IOE and NGT users. Self-perception of comfort, reflux, dietary schedule, social activity, self-esteem, and daily exercise showed significance as intermediate variables between tube feeding modes and anxiety symptoms in path analysis (all p < 0.001). Conclusions: Compared to NGT, IOE can alleviate anxiety symptoms in patients with dysphagia after ischemic stroke who were treated in the Department of Rehabilitation Medicine. The relationship between tube feeding modes and anxiety symptoms was mediated by the self-perception of comfort, reflux, dietary schedule, social activity, self-esteem, and daily exercise.
Reverse switching from the biosimilar SB2 to the originator infliximab in previously switched patients with inflammatory bowel diseases: results of a prospective long-term cohort study
Authors: Fischer Sarah , Donhauser Moritz , Cohnen Sarah , Fietkau Konstantin , Vetter Marcel , Grübel-Liehr Maria , Dietrich Peter , Rath Timo , Wilfer Angelika , Sologub Ludmilla , Krebs Sabine , Dörje Frank , Nagore Daniel , Meyer Sebastian , Neurath Markus F. , Atreya Raja 
Published: November 2024

Background: Data regarding multiple switches including reverse switching between infliximab and its biosimilars are scarce in the field of inflammatory bowel diseases (IBD). Objectives: We investigated the clinical effectiveness as primary outcome measure after repeated switches. Secondary endpoints included C-reactive protein (CRP) levels, immunogenicity (trough levels (TL); anti-drug antibodies (ADA), safety and drug persistence. Design: This study is a prospective, single-centre, observational cohort study. IBD patients receiving originator infliximab were switched to biosimilar SB2 and then reverse switched after 96 weeks and followed up for another 48 weeks. Methods: Clinical disease activity (Harvey–Bradshaw-index (HBI) in Crohn’s disease (CD), partial Mayo score (pMS) in ulcerative colitis (UC)), CRP, TL, ADA, therapy-discontinuations and (serious) adverse events ((S)AE)) were monitored throughout the study. Results: Ninety-five patients (60 CD, 38 female) were enrolled. The median HBI was 2 (interquartile range (IQR) 1–4) at baseline and 2 (1–4) at week 48, resulting in a mean intra-individual change of 0.0 (standard deviation (SD) 1.5). The median pMS was 1 (IQR 0–1) at baseline and 0.5 (0–1) at week 48 resulting in a mean intra-individual change of 0.0 (SD 0.8). Clinical remission was achieved in 80% at baseline and 82% at week 48. Median CRP 2.0 mg/l (IQR 1.0–4.1) at baseline and 2.4 mg/l (1.1–5.2) at week 48 resulted in a mean change of 1.7 (SD 5.8) and no significant differences in CD ( p = 0.3) and UC ( p = 0.9). Median TL were 7.2 µg/ml (IQR 3.8–19.3) at baseline and 5.5 µg/ml (3.5–13.1) at week 48, resulting in a mean change of −1.0 (SD 7.4) with no statistical significance (CD p = 0.26, UC p = 0.41). De-novo-ADA were developed by 3.4%. The discontinuation rate was 14.7%. Safety signals were consistent with previous studies. Conclusion: Reverse switching had no impact on efficacy of infliximab therapy in our cohort of IBD patients. The switch didn’t influence immunogenicity or safety of therapy.
Inflammatory bowel disease in axial spondyloarthritis patients. Is there any specific clinical picture? Data from the RESPONDIA and REGISPONSER registries
Authors: Llop Maria , Gómez-García Ignacio , Gratacós Jordi , Villoria Albert , Calvet Joan , Moreno Mireia , Arévalo Marta , Cabanillas-Paredes Montserrat , Collantes-Estévez Eduardo , Vazquez-Mellado Janitzia , López-Medina Clementina 
Published: November 2024

Background: Inflammatory bowel disease (IBD) affects 5%–10% of ankylosing spondylitis (AS) patients. Prior data suggest AS patients with IBD may have more severe disease and lower HLA-B27 prevalence. Yet, little is known about potential distinctions in AS with IBD compared to those without IBD. Objective: To investigate the clinical characteristics and radiographic differences between patients with (AS) with and without concurrent IBD. Design: This multicenter, observational, cross-sectional study included patients meeting European Spondyloarthropathy Study Group criteria from the Registry of Spondyloarthritis of Spanish Rheumatology (REGISPONSER) and Ibero-American Registry of Spondyloarthropathies (RESPONDIA) registries. Methods: Characteristics and disease burden were compared between patients with and without IBD. Multivariate logistic regression identified factors independently associated with IBD presence in patients with AS. Results: We included a total of 2766 patients with AS (1254 from REGISPONSER and 1512 from RESPONDIA), among whom 142 patients (5.13%) presented with concomitant IBD. AS patients with concurrent IBD were less frequently male, had a lower prevalence of HLA-B27 positivity, experienced a lower prolonged diagnostic delay, had a lower frequency of enthesitis, and received more commonly intensified treatment compared to those without IBD. In terms of structural damage, the Bath Ankylosing Spondylitis Radiology Index (BASRI) score for the sacroiliac joints (SIJs), cervical spine, and lumbar spine was lower in patients with AS and IBD than in those without IBD. In the multivariable analysis, the presence of IBD was significantly associated with a lower prevalence of HLA-B27 and enthesitis, with odds ratios (OR) of 0.32 (95% confidence interval (CI): 0.20–0.52) and 0.58 (95% CI: 0.33–0.97), respectively. Furthermore, structural damage in SIJs (BASRI) was significantly decreased in patients with IBD, with an OR of 0.79 (95% CI: 0.64–0.99). Conclusion: The presence of IBD in AS is associated with lower HLA-B27 positivity, less enthesitis, and less radiographic damage in this large population study.
Efficacy of emicizumab in patients with severe haemophilia A without factor VIII inhibitors in Germany: evaluation of real-life data documented by the smart medication eDiary
Authors: Escuriola Ettingshausen Carmen , Eberl Wolfgang , Eichler Hermann , Fischer Ronald , Hart Christina , Holstein Katharina , Knöfler Ralf , Kreutz Jürgen , Kühnöl Caspar David , Miesbach Wolfgang A. , Pfrepper Christian , Rösch Andreas , Sachs Ulrich J. , Trautmann-Grill Karolin , Mondorf Wolfgang 
Published: November 2024

Background: Systematically documented data on real-world use of emicizumab, a bispecific antibody factor (F)VIII mimetic, are still lacking in people with severe haemophilia A (PwSHA). Smart medication, a real-time, online platform, monitors treatment administration and outcomes for people with haemophilia A in Germany. Objective: To evaluate annualised bleeding rates (ABRs) and annualised joint bleeding rates (AJBRs), using data documented in the smart medication eDiary, for PwSHA receiving emicizumab. Design: Data for 97 PwSHA without FVIII inhibitors who started emicizumab treatment between 1 January 2018 and 31 March 2023, with >24 weeks of documentation after switching from FVIII replacement, were collected in the smart medication eDiary. Those with ⩾24 weeks of pre-emicizumab data were included for analysis 24 weeks before and after switching. Methods: The primary objective was to evaluate ABR and AJBR for treated bleeds. The proportion of bleed-free participants was calculated and administration frequency for FVIII and emicizumab were collected. The mean dosing frequencies for FVIII replacement and emicizumab were also evaluated. Results: The mean calculated ABR and AJBR were 0.64 and 0.39, respectively, after initiating emicizumab. For those with documentation before starting emicizumab ( n = 58), ABR decreased by 79.6% and AJBR decreased by 90.8%. The proportion of bleed-free participants increased by 21.3%, and joint bleed-free participants increased by 18.2%. The median FVIII dosing frequency was every 3.5 days ( n = 54; range: 1.0–20.8); median emicizumab dosing frequency was every 11.2 days ( N = 97; range: 6.6–29.4). Conclusion: Real-world data collected using the smart medication eDiary provide insights into efficacy outcomes after switching from FVIII replacement to emicizumab prophylaxis. Bleeds, including joint bleeds, decreased after switching.