bluuebunny/crossref_metadata_2025_split huggingface dataset:
The singular insemination status of Hypothenemus hampei (Ferrari) (Coleoptera: Curculionidae: Scolytinae) females during the inter-harvest season of a coffee crop
Authors: Román-Ruiz A.K. , Barrera J.F. , Cruz-López L. , Rojas J.C. , Dufour B.P. 
Published: December 2018

AbstractThe coffee berry borer, Hypothenemus hampei (Ferrari), can survive in residual coffee berries during the inter-harvest period, while new fructification only appears 2–3 months after the last harvest. The dispersal of colonizing females is an adaptation that enables the life cycle of the species to go ahead whenever his flight aptitude allows. This paper focuses on accurately determining the rate of inseminated females ready to reproduce when emerging from residuals berries to colonize new ones, which constitutes a characteristic of the live cycle far from common in Curculionidae. We dissected females caught in traps baited with a mixture of alcohols during the inter-harvest season, females from infested residual berries collected from branches, and virgin females obtained from pupae reared individually in the laboratory. After microscopic preparation with Giemsa stain, spermathecae were observed to identify the physiological status of each specimen. Out of the females found in the traps, 98.4% displayed recent and abundant insemination and 1.6% sporadic insemination. In contrast, in residual berries, most of females were recently inseminated (84.5%), followed by virgin females (10.5%) and older inseminated females (5%). In addition, the flight tests of the virgin females were negative. These results indicate that all colonizing females were inseminated, ready for flying and oviposition, females inside residual berries showed different physiological status, and virgin females could not migrate since they could not flight. The large number of inseminated females inside the residual berries, and the capacity of migrating females to colonize and reproduce, suggest that it is necessary to control residual berries and use traps to stop the dispersal and reproduction of this pest.
Could the members of the 1897 Andrée balloon expedition have survived?
Authors: Lantz Björn 
Published: December 2018

AbstractAfter making a final landing with their hydrogen balloon on the Arctic pack ice on 14 July 1897 at 82°56′N 29°52′E, expedition members Salomon August Andrée, Nils Strindberg and Knut Frænkel began a slow march with very heavily laden sledges over the ice to try to reach a depot at Cape Flora. Two fundamental errors regarding where to go and what to bring sealed their fate. This note will explore the theory that, given the information they had at the time, the explorers should not have made these mistakes. In fact, the expedition members could have survived if they had instead travelled directly to their other depot at Seven Islands with more lightly laden sledges.
Implementing the Ridley Report: The Role of Thatcher's Policy Unit during the Miners’ Strike of 1984–1985
Authors: Rawsthorne Phil 
Published: December 2018

AbstractThe Conservative Party has long faced concerns that in regard to the great British miners’ strike of 1984–1985, senior Tories had, in fact, planned the confrontation as early as 1977, when still on the opposition benches. Historian John Savile pointed to the existence of the Ridley Report—a Conservative think-tank paper produced in 1977, which appeared to include a detailed blueprint on how to provoke, and secondly win, a battle against Britain's powerful miners’ union. After Margaret Thatcher's second election victory, and her first landslide, in 1983, the Prime Minister populated the Downing Street Policy Unit with private-sector allies who looked to implement aspects of the report. Some of these allies had clear economic incentives in running down British coal. Nevertheless, the Policy Unit members were instrumental in determining government policy concerning all aspects of the strike, including preparation, policing, the law courts, financial concerns and the portrayal of the strike in the media. The campaign by Thatcher's Policy Unit resulted in a shattering blow for Britain's trade union movement from which it has yet to recover—just as the Ridley Report had predicted.
Insights into soy lecithin and egg yolk-based extenders for chilling canine spermatozoa
Authors: Dalmazzo Andressa , de Souza Ramos Angrimani Daniel , Losano João Diego A. , Rocha Carolina C. , Sobrinho Carlos A. B. , Chinait Gurgel João Rafael , Monteiro Pacheco Pedro Ivo , Minazaki Claudia Kiyomi , Crusco Silvia E. , Nichi Marcilio , Barnabe Valquíria H. 
Published: December 2018

SummaryThe aim of this study was to compare different concentrations of soy lecithin (LEC0.01%, LEC0.05% and LEC0.1%) with egg yolk (Control) in cooling extenders during the storage of semen at 5ºC for 5 days. Twelve dogs (n= 12) were selected, and semen was cooled and assessed after 2, 24, 48, 72, 96 or 120 h. At each time point, sperm were analyzed for kinetic patterns (using computer-assisted sperm analysis), mitochondrial activity (3′3- diaminobenzidine assay), lipid peroxidation (TBARS assay), DNA fragmentation (SCSA®) and plasma and acrosome membrane integrity (eosin/nigrosin and fast green/rose Bengal stains, respectively). The Control group (1814.4 ± 197.2) presented the highest rates of lipid peroxidation at 120 h. Conversely, progressive motility (42.8 ± 4%), linearity (45.4 ± 1%), and VAP (88 ± 3%) were higher in the Control group. In addition, there was lower mitochondrial activity in the Control group at 72 h. Therefore, our data show that lecithin used at these concentrations was not able to maintain sperm viability at as high qualities as would egg yolk. Moreover, the decrease in high mitochondrial activity and the persistence of sperm motility may indicate a compensatory mechanism in canine spermatozoa (i.e., glycolytic pathway). Furthermore, these higher lipid peroxidation indexes could indicate the necessity for future therapy using extenders and antioxidants over a long cooling time for dog sperm.
Evaluation of three dimensional conformal radiation therapy of oesophageal cancer: a dosimetric study
Authors: Zulkafal Hafiz Muhibb ullah , Iqbal Muhammad Mazhar , Akhtar Muhammad Waqas , Iqbal Khalid , Khan Muhammad Afzal 
Published: December 2018

AbstractAimsThe main objective of this research work is to compare the dosimertic effect on lower and upper oesophagus cancer treatment using 3D conformal radiotherapy as well as to evaluate the doses administered to the organs at risk.Materials and methodsIn this study, a cohort of 30 oesophageal cancer patients between the ages of 45 and 67 years registered during March 2017 to February 2018 was considered. These patients were treated through 3D conformal radiotherapy using four-field technique. Beam energy of 15 MV from Varian DHX linear accelerator was used. The given 30 patients were divided into two groups. The 1st group of 15 patients with upper oesophagus cancer was prescribed 5000 cGy doses, and the 2nd group of remaining 15 patients with lower oesophagus cancer was prescribed 4500 cGy. Computed tomography scans of every patient were obtained and then transmitted to Eclipse TPS for generating treatment plans. All radiotherapy plans were evaluated through various dosimetric indices. Statistical analysis software SPSS was utilised to get the values of means standard error and standard deviation of these indices for the treatment plan evaluation.ResultsUniformity index (UI) calculated for first group of patients showed difference of 7·4% from ideal value. A difference of 7% between ideal and calculated UI value was observed in 2nd group of patients. The values of other dosimetric indices like coverage, homogeneity, moderate dose homogeneity index (mDHI) and radical dose homogeneity index (rDHI) were found in limits specified by the Radiation Therapy and Oncology Group. The maximum difference of 6% was observed between the coverage mean values of 1stand 2ndgroup treatment plans.ConclusionFor oesophageal cancer, 3D conformal radiotherapy using four-field treatment plans shows homogeneous distribution of dose around the target and limits the dose to organ at risk.
On the effect of financial education on financial literacy: evidence from a sample of college students
Authors: Brugiavini Agar , Cavapozzi Danilo , Padula Mario , Pettinicchi Yuri 
Published: December 2018

AbstractBased on a sample of university students, we provide evidence that a small-scale training intervention has both a statistically and economically significant effect on subjective and objective assessments of financial knowledge. We also show that the intervention increases self-assessed more than actual financial knowledge. The intervention consists of measuring financial literacy before and after a small on-line course and is administered through an on-line platform.
Integrated Petrological and Geophysical Constraints on Magma System Architecture in the Western Galápagos Archipelago: Insights From Wolf Volcano
Authors: Stock Michael J. , Bagnardi Marco , Neave David A. , Maclennan John , Bernard Benjamin , Buisman Iris , Gleeson Matthew L. M. , Geist Dennis 
Published: December 2018

AbstractThe 2015 eruption of Wolf volcano was one of the largest eruptions in the Galápagos Islands since the onset of routine satellite‐based volcano monitoring. It therefore provides an excellent opportunity to combine geophysical and petrological data, to place detailed constraints on the architecture and dynamics of subvolcanic systems in the western archipelago. We present new geodetic models that show that pre‐eruptive inflation at Wolf was caused by magma accumulation in a shallow flat‐topped reservoir at ~1.1 km, whereas edifice‐scale deformation during the eruption was related to a deflationary source at 6.1–8.8 km. Petrological observations suggest that the erupted material was derived from both a subvolcanic mush and a liquid‐rich magma body. Using a combination of olivine‐plagioclase‐augite‐melt (OPAM) and clinopyroxene‐melt barometry, we show that the majority of magma equilibration, crystallization, and mush entrainment occurred at a depth equal to or greater than the deep geodetic source, with little petrological evidence of material sourced from shallower levels. Hence, our multidisciplinary study does not support a fully transcrustal magmatic system beneath Wolf volcano before the 2015 eruption but instead indicates two discrete storage regions, with a small magma lens at shallow levels and the major zone of magma storage in the lower crust, from which most of the erupted material was sourced. A predominance of lower crustal magma storage has previously been thought typical of subvolcanic systems in the eastern Galápagos Archipelago, but our new data suggest that this may also occur beneath the more active volcanoes of the western archipelago.
Transcriptional landscape of mouse-aged ovaries reveals a unique set of non-coding RNAs associated with physiological and environmental ovarian dysfunctions
Authors: Cuomo Danila , Porreca Immacolata , Ceccarelli Michele , Threadgill David W. , Barrington William T. , Petriella Annacristina , D’Angelo Fulvio , Cobellis Gilda , De Stefano Francesca , D’Agostino Maria N. , De Felice Mario , Mallardo Massimo , Ambrosino Concetta 
Published: December 2018

AbstractThe progressive and physiological decline in ovarian function depends on the rate of follicular loss by atresia, contributing to the reduction in ovarian reserve. Genetics and environmental factors play important roles in ovarian senescence and in the onset of ovarian dysfunctions such as diminished ovarian reserve. A better understanding of the mechanisms underlying ovarian aging and their regulation by genetic and environmental factors is needed to evaluate ovarian reserve and to predict fertility potential by identification of more accurate and less invasive markers. We report transcriptomic data (i) implicating novel (e.g. EIF2 signalling) and well-known pathways (e.g. TGFβ signalling), and (ii) defining a unique set of non-coding RNA (ncRNA), both associated with ovarian function. The latter includes miRNAs (e.g.Mir143andMir145), snoRNAs (e.g.Snord16aandSnora34), and one lncRNA (Gas5), which are differentially expressed in middle-aged ovaries (12 months)vsyoung-aged (3 months) from CD1 mice. Experimental analysis confirms that ovary lifespan varies across genetic backgrounds in mice and, genetics influences the response to environmental perturbations such as diet. Moreover, the identified ncRNAs were verified in a model of reproductive dysfunction promoted by the environmental toxicant ethylenthiourea. We also report the increase of miRNA143 and miRNA145 in follicular fluid of women with diminished ovarian reserve. Their levels inversely correlate with the hormonal profile and with the number of the oocytes recruited upon hormonal stimulation. Overall, we report a transcriptomic signature for ovarian dysfunction in vivo that provides a valuable resource for translational research in human reproductive aging.
NAD(P)H quinone oxidoreductase (NQO1): an enzyme which needs just enough mobility, in just the right places
Authors: Pey Angel L. , Megarity Clare F. , Timson David J. 
Published: December 2018

Abstract
NAD(P)H quinone oxidoreductase 1 (NQO1) catalyses the two electron reduction of quinones and a wide range of other organic compounds. Its physiological role is believed to be partly the reduction of free radical load in cells and the detoxification of xenobiotics. It also has non-enzymatic functions stabilising a number of cellular regulators including p53. Functionally, NQO1 is a homodimer with two active sites formed from residues from both polypeptide chains. Catalysis proceeds via a substituted enzyme mechanism involving a tightly bound FAD cofactor. Dicoumarol and some structurally related compounds act as competitive inhibitors of NQO1. There is some evidence for negative cooperativity in quinine oxidoreductases which is most likely to be mediated at least in part by alterations to the mobility of the protein. Human NQO1 is implicated in cancer. It is often over-expressed in cancer cells and as such is considered as a possible drug target. Interestingly, a common polymorphic form of human NQO1, p.P187S, is associated with an increased risk of several forms of cancer. This variant has much lower activity than the wild-type, primarily due to its substantially reduced affinity for FAD which results from lower stability. This lower stability results from inappropriate mobility of key parts of the protein. Thus, NQO1 relies on correct mobility for normal function, but inappropriate mobility results in dysfunction and may cause disease.
The Effects of Static and Moving Spectral Ripple Sensitivity on Unaided and Aided Speech Perception in Noise
Authors: Miller Christi W. , Bernstein Joshua G. W. , Zhang Xuyang , Wu Yu-Hsiang , Bentler Ruth A. , Tremblay Kelly 
Published: December 2018

Purpose
This study evaluated whether certain spectral ripple conditions were more informative than others in predicting ecologically relevant unaided and aided speech outcomes.

Method
A quasi-experimental study design was used to evaluate 67 older adult hearing aid users with bilateral, symmetrical hearing loss. Speech perception in noise was tested under conditions of unaided and aided, auditory-only and auditory–visual, and 2 types of noise. Predictors included age, audiometric thresholds, audibility, hearing aid compression, and modulation depth detection thresholds for moving (4-Hz) or static (0-Hz) 2-cycle/octave spectral ripples applied to carriers of broadband noise or 2000-Hz low- or high-pass filtered noise.

Results
A principal component analysis of the modulation detection data found that broadband and low-pass static and moving ripple detection thresholds loaded onto the first factor whereas high-pass static and moving ripple detection thresholds loaded onto a second factor. A linear mixed model revealed that audibility and the first factor (reflecting broadband and low-pass static and moving ripples) were significantly associated with speech perception performance. Similar results were found for unaided and aided speech scores. The interactions between speech conditions were not significant, suggesting that the relationship between ripples and speech perception was consistent regardless of visual cues or noise condition. High-pass ripple sensitivity was not correlated with speech understanding.

Conclusions
The results suggest that, for hearing aid users, poor speech understanding in noise and sensitivity to both static and slow-moving ripples may reflect deficits in the same underlying auditory processing mechanism. Significant factor loadings involving ripple stimuli with low-frequency content may suggest an impaired ability to use temporal fine structure information in the stimulus waveform. Support is provided for the use of spectral ripple testing to predict speech perception outcomes in clinical settings.
The Relationship Between Non-Orthographic Language Abilities and Reading Performance in Chronic Aphasia: An Exploration of the Primary Systems Hypothesis
Authors: Madden Elizabeth Brookshire , Conway Tim , Henry Maya L. , Spencer Kristie A. , Yorkston Kathryn M. , Kendall Diane L. 
Published: December 2018

Purpose
This study investigated the relationship between non-orthographic language abilities and reading in order to examine assumptions of the primary systems hypothesis and further our understanding of language processing poststroke.

Method
Performance on non-orthographic semantic, phonologic, and syntactic tasks, as well as oral reading and reading comprehension tasks, was assessed in 43 individuals with aphasia. Correlation and regression analyses were conducted to determine the relationship between these measures. In addition, analyses of variance examined differences within and between reading groups (within normal limits, phonological, deep, or global alexia).

Results
Results showed that non-orthographic language abilities were significantly related to reading abilities. Semantics was most predictive of regular and irregular word reading, whereas phonology was most predictive of pseudohomophone and nonword reading. Written word and paragraph comprehension were primarily supported by semantics, whereas written sentence comprehension was related to semantic, phonologic, and syntactic performance. Finally, severity of alexia was found to reflect severity of semantic and phonologic impairment.

Conclusions
Findings support the primary systems view of language by showing that non-orthographic language abilities and reading abilities are closely linked. This preliminary work requires replication and extension; however, current results highlight the importance of routine, integrated assessment and treatment of spoken and written language in aphasia.

Supplemental Material

https://doi.org/10.23641/asha.7403963
Modifying and Validating a Measure of Chronic Stress for People With Aphasia
Authors: Hunting Pompon Rebecca , Amtmann Dagmar , Bombardier Charles , Kendall Diane 
Published: December 2018

PurposeChronic stress is likely a common experience among people with the language impairment of aphasia. Importantly, chronic stress reportedly alters the neural networks central to learning and memory—essential ingredients of aphasia rehabilitation. Before we can explore the influence of chronic stress on rehabilitation outcomes, we must be able to measure chronic stress in this population. The purpose of this study was to (a) modify a widely used measure of chronic stress (Perceived Stress Scale [PSS]; Cohen & Janicki-Deverts, 2012) to fit the communication needs of people with aphasia (PWA) and (b) validate the modified PSS (mPSS) with PWA.MethodFollowing systematic modification of the PSS (with permission), 72 PWA completed the validation portion of the study. Each participant completed the mPSS, measures of depression, anxiety, and resilience, and provided a sample of the stress hormone cortisol extracted from the hair. Pearson's product–moment correlations were used to examine associations between mPSS scores and these measures. Approximately 30% of participants completed the mPSS 1 week later to establish test–retest reliability, analyzed using an interclass correlation coefficient.ResultsSignificant positive correlations were evident between the reports of chronic stress and depression and anxiety. In addition, a significant inverse correlation was found between reports of chronic stress and resilience. The mPSS also showed evidence of test–retest reliability. No association was found between mPSS score and cortisol level.ConclusionAlthough questions remain about the biological correlates of chronic stress in people with poststroke aphasia, significant associations between chronic stress and several psychosocial variables provide evidence of validity of this emerging measure of chronic stress.
Frequencies in Perception and Production Differentially Affect Child Speech
Authors: Richtsmeier Peter T. , Good Amanda K. 
Published: December 2018

Purpose
Frequent sounds and frequent words are both acquired at an earlier age and are produced by children more accurately. Recent research suggests that frequency is not always a facilitative concept, however. Interactions between input frequency in perception and practice frequency in production may limit or inhibit growth. In this study, we consider how a range of input frequencies affect production accuracy and referent identification.

Method
Thirty-three typically developing 3- and 4-year-olds participated in a novel word-learning task. In the initial test block, participants heard nonwords 1, 3, 6, or 10 times—produced either by a single talker or by multiple talkers—and then produced them immediately. In a posttest, participants heard all nonwords just once and then produced them. Referent identification was probed in between the test and posttest.

Results
Production accuracy was most clearly facilitated by an input frequency of 3 during the test block. Input frequency interacted with production practice, and the facilitative effect of input frequency did not carry over to the posttest. Talker variability did not affect accuracy, regardless of input frequency. The referent identification results did not favor talker variability or a particular input frequency value, but participants were able to learn the words at better than chance levels.

Conclusions
The results confirm that the input can be facilitative, but input frequency and production practice interact in ways that limit input-based learning, and more input is not always better. Future research on this interaction may allow clinicians to optimize various types of frequency commonly used during therapy.
Precision study of satellite levelling with using various models of geoid
Authors: Buczyńska Anna 
Published: December 2018

The main purpose of this study is comparison of orthometric heights of measuring points and the accuracy of these heights depending on selected geoid model and measurement method. In addition, for better understanding of the essence of conducted research, paper provides information about:

geoid and other surfaces used in geodesy to describe the terrestrial globe,
modelling methods of equipotential surfaces and data that can be used to develop them,
the most important geoid models developed for the area of Poland and the world,
the technique of determining the orthometric heights using various measuring methods.

Heights of two measuring points, located on the premises of Wrocław University of Science and Technology, were determined to achieve thesis statement. The scope of the study is limited to determining the orthometric heights of points for three global geoid models and four geoid models developed for the area of Poland. Among the selected equipotential surfaces were: geoida niwelacyjna 2000, GUGiK 2001, GEOIDPOL 2008A/C/CN, PL-GEOID-2011, OSU91, EGM96 and EGM2008.