bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disentangling the effects of empathy components on Internet gaming disorder: A study of vulnerable youth in China
Authors: Hui Bryant P. H. , S. Wu Anise M. , Pun Ngai 
Published: March 2019

Background and aims
Previous research shows that empathy can be one of the potential protective factors for Internet gaming disorder (IGD), yet the complex relationships between multidimensional factors of empathy and IGD remain understudied. Thus, a major question moving forward is to resolve the mixed empirical data by examining the specific contributions of empathy components. In this study, we disentangle the effects of cognitive component (i.e., perspective taking) and affective component (i.e., empathic concern and personal distress) on IGD symptoms and propose affect-oriented mediation pathways between them.

Methods
We surveyed a large sample (N = 3,348) of Chinese vocational school students, one of the most vulnerable groups to online gaming addiction.

Results
Our structural equation modeling results revealed that only personal distress, but not empathic concern or perspective taking, positively predicted IGD symptoms. However, empathic concern and personal distress were negatively and positively predicted gaming motive of escape from reality, respectively, which in turn predicted IGD symptoms. Furthermore, we found an indirect effect of perspective taking on IGD through empathic concern and then gaming motive of escape from reality.

Discussion and conclusion
The findings underscore the importance of separating the affective and cognitive components to understand the complex relationships between the empathy and IGD, and support our theorizing of the affect-oriented mediation mechanism.
Reflection of Teacher’s Interpersonal Skill: Describing The Quality of An Effective Teacher
Authors: Hastowohadi Hastowohadi 
Published: March 2019

There are six characteristics that can not be taught, only modeled, they are Caring, Fairness and Respect, Attitude toward the Teaching Profession, Social Interaction with Students, Promotion of Enthusiasm and Motivation for Learning, Reflective Practice. The aspect of teacher as a person is only one of six aspects that should be modeled and demonstrate to the students. But, this aspect is going to be left by teachers in this era. It will be monotonous teacher as a leader and messenger in holding the whole class of teaching-learning activity. Furthermore, in this research, the writer wants to explore and find out what are actually the problems of this issue. The research was done in SMK Visi Global in Banyuwangi and took 6 teachers as an object of research. The writer used descriptive qualitative and describing the phenomenon of this. Indeed, the result was Fairness and Respect, Attitude toward Teaching Profession, Enthusiasm, and Motivation for Learning, and Reflective Practice got above average but Caring, Social Interaction with Students got below average. This issue described that the teachers in SMK Visi Global were not enlightened by a good teacher as a person and it would be ineffective for the school and students itself. It can be concluded that preparing teacher‟s personality is unavoidable for the professional teacher, in this era or future.
Twitter for Educational Activities in Islamic Higher Education, Why Not?
Authors: Yudhiantara Rully Agung 
Published: March 2019

This research was motivated by the need to combine the trend of using twitter among university students and the need of online educational activities. The study was aimed at investigating: twitter usage between Teacher and students for educational activities.2)discovering students perception on twitter usage for educational activities. This study found that twitter was used for educational activities by teacher and students. The activities occured namely; sharing information,asking and answering, and assigning task. In addition twitter was also used by student to save their document on learning process. Last findings showed that students perceived twitter in a positive manner and they appreciated twitter usage for educational activities.
THE EVALUATION OF BOBBY BOLA DAN PERI BUKU AJAIB 3 FOR LANGUAGE LEARNING
Authors: Hendryani Rika 
Published: March 2019

Video games have received much attention in recent years as a tool for foreign language learning. Number of research has shown the positive impact of video games on language learning learners. This study is aimed to find out the extent to which Bobby Bola & Peri Buku Ajaib 3 meet the 10 principles for designing video games for foreign learning proposed by Purushotma, Thorne, and Wheatley (2009). The findings of this study show that Bobby Bola & Peri Buku Ajaib 3 adhere only to 2 principles, i.e., the principles of “communication and input mechanism should have a playful spirit to them” and “students should be allowed to spend extra time in activities they enjoy and to minimize time in ones they don't”. The result of this study hopefully would be beneficial to the studies of video games for foreign language learning. It is also hoped that it can provide further information for those who wish to evaluate or use video games as a language learning tool.
microRNA-431 as a Chemosensitizer and Potentiator of Drug Activity in Adrenocortical Carcinoma
Authors: Kwok Grace T.Y. , Zhao Jing Ting , Glover Anthony R. , Gill Anthony J. , Clifton-Bligh Roderick , Robinson Bruce G. , Ip Julian C.Y. , Sidhu Stan B. 
Published: March 2019

Abstract

Background
Adrenocortical carcinoma (ACC) is a rare endocrine cancer with treatments limited in efficacy for metastatic disease. New molecular targeted therapies have yet to improve patient outcomes. In contrast, established treatment regimens of adrenolytics and chemotherapy have demonstrated treatment benefit, although admittedly in a minority of patients. Identification of microRNAs (miRNAs) in patients responsive to adjuvant therapy may offer a means to sensitize patients with progressive disease to existing adjuvant regimens.

Materials and Methods
Samples from primary ACC tumors of 10 Stage IV patients were examined for differentially expressed miRNAs between a “sensitive” and “resistant” cohort. Candidate microRNAs were restored via transfection in two functional ACC cell lines. Gain of function and effects on apoptosis and cell cycle were assessed.

Results
microRNA-431 (miR-431) was underexpressed in patients with ACC with progressive disease undergoing adjuvant therapy. Restoration of miR-431 in vitro decreased the half maximal inhibitory concentrations of doxorubicin and mitotane, with markedly increased apoptosis. We found that a reversal of epithelial-mesenchymal transition underlies the action of miR-431 with doxorubicin treatment, with Zinc Finger E-Box Binding Homeobox 1 implicated as the molecular target of miR-431 in ACC.

Conclusion
This is the first report of the potential of miRNA therapy to sensitize ACC to current established adjuvant therapy regimens, which may mitigate the resistance underlying treatment failure in patients with advanced ACC. Effective and well-studied methods of targeted miRNA delivery in existence hints at the imminent translatability of these findings.
Comparative study of etiological profile and outcome in acute liver failure
Authors: Nabi Tauseef , Rafiq Nadeema , Jamil Imran 
Published: March 2019

<p class="abstract"><strong>Background:</strong> Acute liver failure (ALF) is a clinical syndrome that is marked by the sudden loss of hepatic function in a person without chronic liver disease. Clinical and etiological profile varies with geographical area and over time. The objective of this prospective study was to determine the etiological profile and outcome of ALF and to compare it with other major studies from India and US.</p><p class="abstract"><strong>Methods:</strong> A total of 84 consecutive patients with a diagnosis of ALF were included in the study. The variables evaluated were demographic, signs and symptoms, biochemical parameters, etiological profile and outcome. </p><p class="abstract"><strong>Results:</strong> Viral hepatitis 32 (38.1%) was the most common cause of ALF but large number of the patients 30 (35.7%) had indeterminate aetiology. Among viral causes, acute hepatitis E (19.1%) was most common followed by hepatitis B (9.5%) and A (9.5%). Drug or toxic induced liver failure (17.8%) also contributed a significant proportion. Majority of the patients were male (51.9%) and the mean age was 39.48±20.11 years. Aetiology varied with other geographical area and even over time in the same area. Overall mortality was 44 (57.1%) in ALF patients, with highest mortality in indeterminate group (60%).</p><p class="abstract"><strong>Conclusions:</strong> Like the rest of India, viral hepatitis was the common cause of ALF but a large number of patients 30 (35.7%) had indeterminate aetiology. Overall mortality was 57.1%. Our study highlights the differences in the profile of ALF from other earlier studies in India and the west.</p>
Aortic Valve Myxoma Presenting with a Stroke: A case report and review of the literature
Authors: Alkuwaiti Feras A. , Elghoneimy Yasser , Ghazal Sami 
Published: March 2019

Myxomas originating from the aortic valve are rare. We report a 40-year-old male patient who presented to the King Fahd Hospital of the University, Khobar, Saudi Arabia, in 2017 with a stroke. Transoesophageal echocardiography indicated a mobile mass measuring 6 × 2 mm attached to the right coronary cusp of the aortic valve and a mobile interatrial septum with a small patent foramen ovale (PFO). The patient underwent surgical excision of the mass and direct closure of the PFO. Histopathology confirmed the mass to be a myxoma. Despite their rarity, the recognition and treatment of valvular myxomas is very important; moreover, clinicians should be aware that affected patients may present with an embolic stroke.Keywords: Aortic Valve; Myxoma; Patent Foramen Ovale; Stroke; Transesophageal Echocardiography; Case Report; Saudi Arabia.
Job demands and resources scale for physical education teachers: Is it valid in Turkish culture?
Authors: Engur Mustafa , Kiremitci Olcay , Boz Berkcan 
Published: March 2019

The aim of the study was to adapt job demands and resources scale for Physical Education (PE) teachers into Turkish language. Two hundered and nineteen PE teachers participated in this study. In the scope of validity analyses of the scale, different techniques were used and expert opinion was obtained for the language content validity, while exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were performed for construct validity. Results of EFA showed that two main factors explained 34.91% of variance. CFA results revealed that the indices examined in terms of construct were at a good level with regards to data fit. In reliability analyses, internal consistency coefficient was calculated as 0.74 for the whole, 0.81 for job demands and 0.74 for job resources from the main factors. Results reveal that job demands-resources scale for PE teachers is reliable and valid for Turkish population.

Keywords: Physical education teacher, job demands, job resources, validity, reliability.
Social and psychological features of inter-cultural adaptation of Russian students in different universities
Authors: Kolesnikov Alexey A. , E. Nikulina Darya , Danilenko Ilya A. , Zimovets Natalya V. 
Published: March 2019

Modern globalisation processes, the rapid entry of Russia into the world community, have given more opportunities to interact with various ethnic groups ranging from short-term tourist and business contacts to complex processes of migration and emigration. Migrants and visitors have different goals for staying in a new country, meanwhile the researchers note a lot in common within the adaptation processes of both groups. In particular, tension, stresses and experience of cultural shock during adaptation are observed. Therefore, it is necessary to conduct psychological studies not only of migrants who come for a long time to a new country, but also of visitors, i.e., interns, students who come to study in foreign universities. Anyway, all migrants face difficulties in interacting with local residents whose behaviour cannot be predicted. The host countryâ€™s customs often seem mysterious to them, and people seem strange.
Keywords: Adaptation, bologna process, ethnopsychology, exchange students.
The ability to perform a post-traumatic examination as an indicator of the effects of teaching emergency medicine at the successive stages of the educational process: medical students, trainee physicians.
Authors: Pakulski Cezary , Denisiuk Maciej 
Published: March 2019

Introduction. Emergency management at the accident site is often of key importance for the later fate of patients who have sustained severe injuries. The scheme for post-traumatic examination has been developed to improve dealing with trauma patients.Aim. The aim of this study was to analyze the effects of teaching emergency medicine to students and graduates of the Faculty of Medicine in Szczecin, on the basis of their ability to carry out post-traumatic examination. The skills at recognizing a direct threat to life and performing basic life-saving procedures were appraised. Material and Methods. The study involved 81 individuals, who were evaluated three times at different stages of their educational process. Groups I and II comprised of fifth year students before and after an emergency medicine course, and group III consisted of trainee physicians. The Laerdal MegaCode Kelly manikin was employed in the project. Each of the simulated patients had the same external injury symptoms and parameters of vital functions.Results. Evaluation of vital functions was correctly done by 14.8% of group I, 59.3% of group II, and no one in group III. A quick post-traumatic examination was performed properly by 11.2% of group I, 55.5% of group II, and no one in group III.Conclusions. Group I lacked the ability to perform post-traumatic examination and first aid procedures. Participation in emergency medicine courses had positive effects on the participants’ skills (group II). The ability of trainee physicians (group III) to perform the majority of the tested elements of post-traumatic examination, including first aid procedures, noticeably declined and reached the initial level.
Women and men diagnosed with acute coronary syndrome – sex-related differences
Authors: Dudek Magdalena , Kałużna-Oleksy Marta , Migaj Jacek , Straburzyńska-Migaj Ewa 
Published: March 2019

Background. Coronary artery disease (CAD) is one of the most important causes of death in both men and women. There are many gender differences among patients with CAD, including risk factors and acute coronary syndrome (ACS) outcomes. The latest reports showed that mortality due to CAD is higher in women than in men. Cardiac biomarkers play an important role in risk stratification and choice of treatment strategy in patients with ACS, however some of cardiac biomarkers show worse sensitivity and specificity in women.Aim. The aim was to investigate the sex-related differences in patients with acute coronary syndrome and to compare their sex-related risk of in-hospital mortality.Material and Methods. Single-center study of patients diagnosed with ACS who underwent precutaneous coronary intervention (PCI). Patients were diagnosed and treated according to ESC Guidelines. Statistical analysis was performed using StatSoft Statistica.Results. Of the 297 patients included in this study, 32% were women and 68% were men. There were 26.94% STEMI patients, 22.22% NSTEMI patients and 50.84% unstable angina patients. Compared with males, females were significant older (68.2 ± 10.6 vs. 64.8 ± 11.0; p = 0.0175). Levels of biomarkers of myocardial injury were significantly lower in women: CK-MB (p = 0.0241), troponin I (p = 0.0417) and CK (p = 0.0035) than in men. Women were less frequently treated with PCI or CABG (p = 0.0016) but the in-hospital outcomes (cardiogenic shock, sudden cardiac arrest or cardiac death) were similar in both groups (p = 0.8557).Conclusions. Women with ACS were older and have higher incidence of non-ST-elevation ACS than men.. In-hospital mortality show no significant difference between genders. Women were less likely to receive invasive treatment.
Are risk factors of cerebral small vessel disease differ from those in patients with high atherothrombotic risk without cerebrovascular disease?
Authors: Staszewski Jacek , Skrobowska Ewa , Piusińska-Macoch Renata , Brodacki Bogdan , Stępień Adam 
Published: March 2019

Knowledge of risk factors for cerebral small vessel disease (CSVD) may generate hypothesis regarding possible targets for prevention. Our aim was to evaluate if atherothrombotic risk factors differ between patients with CSVD and with subjects without cerebrovascular disease but with high cardiovascular (CVD) risk. A single-center, cohort study was performed in consecutive patients with different CSVD manifestations. The study group consisted of 205 patients: 52 with lacunar stroke (LS), 20 with subcortical hemorrhagic stroke (HS), 50 with vascular dementia (VaD), 28 with vascular parkinsonism (VaP) and 55 controls (CG) with high CVD risk (35 with atherosclerotic CVD, 20 with 10-year risk of CVD with SCORE?5). Logistic regression was used to analyze the influence of clinical and laboratory data on the occurrence of CSVD. Mean age, sex distribution, prevalence of smoking, hyperlipidemia, peripheral artery disease and obesity were similar in CSVD and CG. The factors significantly associated with CSVD compared to controls were diabetes mellitus, polymetabolic syndrome, elevated systolic blood pressure, low levels of eGFR, HDL, albumin and high uric acid, fibrinogen, fasting glucose, HbA1c and intima medic thickness (p<0.05). Hypertension, chronic kidney disease and elevated fasting blood glucose were related to LS and HS (p<0.1). Diabetes was significantly associated with LS and VaD while smoking and low total cholesterol were related to HS (p<0.1). The study confirms that risk factors profile for CSVD differs from subjects with proatherogenic profile without history of cerebrovascular disease. Our results also support that unique risk factors profiles exist for different manifestations of the CSVD.
Femoral Neck Fracture Fixation with a Medial Buttress Plate That Led to Impingement with Hip Flexion
Authors: Marchand Lucas S. , Karns Michael , Higgins Thomas F. , Aoki Stephen K. 
Published: March 2019

Case:
A 47-year-old man with an isolated femoral neck fracture was treated with open reduction and internal fixation with a medial femoral neck buttress plate and a dynamic hip screw. Union was achieved without osteonecrosis of the femoral head. However, hip arthroscopy that was performed for persistent hip pain following the fracture union revealed an intra-articular impingement of the buttress plate and a substantial anterior acetabular chondral injury.

Conclusions:
To our knowledge, this is the first reported complication associated with the application of a medial buttress plate for a femoral neck fracture. This case report may help surgeons who employ this technique to avoid a similar complication.
Successful Fixation of a Tuberculous Nonunion of the Humeral Shaft
Authors: Patel Ronak M. , Miller Anna N. 
Published: March 2019

Case:
A 48-year-old man from North Africa with a history of infection after fixation of a humeral fracture presented 8 years later with an infected nonunion. After operative debridement, Mycobacterium tuberculosis grew on culture. Following a 2-stage surgical procedure and medical management of the tuberculosis (TB), successful union had been achieved at the 1-year follow-up.

Conclusion:
Nonunion of the humerus caused by TB is a rare entity, but careful attention to patient demographics can forewarn the care provider. Irrigation and debridement with the Masquelet technique followed by compression plating and an iliac crest autograft can provide positive results.
DOENÇAS DIAGNOSTICADAS PELO LABORATÓRIO DE PATOLOGIA VETERINÁRIA EM 2016
Authors: Carneiro Christofe , Piva Manoela M. , Gris Anderson , Cechin Renan A. , Rhoden Leandro A. , Santiani Fabio , Gomes Denilso J. , Stedille Fernanda A. , Baldi Kelen R. A. , Gomes Teane M. A. , Mendes Ricardo E. 
Published: March 2019

Este trabalho apresenta a casuística de diagnósticos no ano de 2016 do Laboratório de Patologia Veterinária do IFC Campus Concórdia. Foram 236 diagnósticos em bovinos, 31 em ovinos e 125 em suínos, totalizando 392. Destes, 268 (68,4%) foram através de necropsias e 124 (31,6%) através de amostras formolizadas enviadas por veterinários. Em bovinos as doenças mais incidentes foram miosite clostridial com 16 casos (6,8%); leucose enzoótica bovina com 9 casos (3,8%); salmonelose com 8 casos (3,4%); intoxicação por nitrato/nitrito com 8 casos (3,4%); hemoncose com 7 casos (3,1%) e anaplasmose com 6 casos (2,6%). Já em ovinos foi hemoncose com 6 casos (19,4%) e em suínos doença de Glässer com 8 casos (6,4%); circovirose com 6 casos (4,8%) e raquitismo com 6 casos (4,8%).
DOENÇAS DIAGNOSTICADAS PELO LABORATÓRIO DE PATOLOGIA VETERINÁRIA EM 2017
Authors: Carneiro Christofe , Gris Anderson , Cechin Renan A. , Mingotti Taisson R. , Bavaresco Lucas H. , Carneiro Daniele C. S. , Miglioranza Débora , Alves Felipe D. , Freyer Max J. , Gomes Teane M. A. , Mendes Ricardo E. 
Published: March 2019

Este trabalho apresenta a casuística de diagnósticos no ano de 2017 do Laboratório de Patologia Veterinária do IFC Campus Concórdia. Foram 230 diagnósticos em bovinos, 32 em ovinos e 93 em suínos, totalizando 355. Destes, 247 (69,6%) foram através de necropsias e 108 (30,4%) através de amostras formolizadas enviadas por veterinários. Em bovinos as doenças mais incidentes foram anaplasmose e babesiose com 11 casos cada (4,8%); endocardite com 7 casos (3,0%); hemoncose com 6 casos (2,6%) e retículo pericardite traumática com 6 casos (2,6%). Já em ovinos foi hemoncose com 5 casos (15,7%) e suínos doença de Glässer e colibacilose com 6 casos cada (6,4%).
Magnesium sulfate decreases the dose of rocuronium for satisfactory double lumen tube placement condition in patients with myasthenia gravis
Authors: Fei Shoujun , Xia Hengfu , Chen Xiaowei , Pang Dazhi , Xu Xuebing 
Published: March 2019

Abstract
Background: Titrating a low dose of non-depolarizing neuromuscular blockers for induction of general anesthesia for patients with myasthenia gravis (MG) is a popular accepted practice. This practice may confront with unsatisfactory intubation conditions, especially for double lumen tube (DLT). This double-blind randomised study was to investigate whether magnesium sulfate could decrease the rocuronium demand and improve the DLT placement conditions for MG patients who scheduled for video-assisted thoracoscopic (VATS) thymectomy.
Methods: The patients were randomly assigned into the magnesium sulfate or normal saline group. After acquiring the adequate sedative depth, magnesium sulfate(60mg.kg-1) or normal saline(control) was given to the patients in two groups respectively. After that, the same Train of Four (TOF) value was obtained with one or more doses of 0.05 mg.kg-1 rocuronium with 3 minutes interval, then DLT was intubated. The primary and secondary observational outcomes were the cumulative rocuronium dose and the intubation condition for DLT placement respectively.
Results: 23 patients in the magnesium sulphate group and 22 patients in the control group completed the study. The amount of rocuronium used to meet the setting value of TOF were 0.10 (0.05)mg.kg-1 and 0.28(0.17) mg.kg-1 in the magnesium sulphate and control group respectively (P<0.0001). Under a similar depth of neuromuscular blockade and sedation, 23 patients in magnesium sulphate group and 16 patients in control group showed excellent intubation condition. The patients in both groups showed similar characteristics of recovery from neuromuscular blockade.
Conclusions: Our research showed that magnesium sulfate could decrease the rocuronium demand for satisfactory DLT intubation condition in MG patients.