bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Collagen Activation on Platelet Rich Plasma for Proliferation of Periodontal Ligament Fibroblasts
Authors: Tangsupati Pati , Murdiastuti Kwartarini 
Published: December 2018

BACKGROUND: Regenerative procedure in periodontal surgery aims to improve the structure and function of the periodontium to be strong enough to support the teeth. Growth factor is essential in the process of tissue regeneration; it can be generated from the activation of Platelet-Rich Plasma (PRP). In this study, collagen was used as PRP activator. PRP release growth factor from the granules when activated. The aim of this study was to evaluate the effect of collagen on PRP activation and the collagen-activated PRP storage to fibroblast proliferation of periodontal ligament (PDL).METHODS: Fibroblasts of PDL were obtained from extracted premolar. PRP were obtained from 100 mL of blood donors using double centrifugation methods. PRP were activated by collagen and subsequently incubated for 24, 48, 72 and 168 hours; after which the lysate was taken. Fibroblasts were divided into 7 groups, which consisted of one unstimulated group as negative control, one group stimulated by PRP lysate, and five groups stimulated with PRP-collagen lysates that had been incubated for 24, 48, 72 and 168 hours. MTT assay was then performed after 1 and 3 days.RESULTS: The proliferation rate of fibroblasts group stimulated by PRP-collagen lysate was higher than the group stimulated by PRP. The storage of collagen-activated PRP for 7 days at 4°C could increase the proliferation rate.CONCLUSION: The activation of collagen on PRP and the stored collaged-activated PRP could increase the fibroblasts proliferation rate of PDL.KEYWORDS: collagen, platelet-rich plasma, fibroblasts proliferation
Inhibition of DNase I Enzyme with Nickel(II) Triphenylphosphine Complexes Incorporating Tridentate Schiff Base Ligands in Vitro
Authors: GÜVELİ Şükriye 
Published: December 2018

The
nickel(II) complexes containing 3-methoxy-salicylaldehyde-N4-R thiosemicarbazones
(R:-H2,-propyl)with triphenylphosphine coligands have been
synthesized. The structure of Ni(II)-centered metal complex was approved by
elemental analysis and melting point. The solid-state structure of complex 2 bearing PPh3 as co-ligand was
clarified by single crystal X-ray crystallography, which revealed square planar
geometry around Ni(II) ion. Thiosemicarbazone
ligands are coordinated by ONS mode to nickel(II). The potential of these complexes to inhibit the DNase I enzyme, which
uses DNA as a substrate, was investigated in vitro. The results revealed that
the compounds inhibited the DNase enzyme in directly and/or indirectly (by
masking of DNA molecules) at ≥0.1 µg/ml concentrations in vitro.
A novel Benzimidazole moiety-appended Schiff base derivative: Synthesis, characterization and the investigation of photophysical and chemosensor properties
Authors: ŞEN Pınar , YILDIZ Salih Zeki , DEGE Necmi , ATMACA Göknur Yaşa , ERDOĞMUŞ Ali , DEGE Mustafa 
Published: December 2018

In this study, we synthesized a novel
benzimidazole-based Schiff base;
(E)-4,4'-methylenebis(2-((E)-(((1H-benzo[d]imidazol-2-yl)methyl)imino)methyl)phenol)
(3) was synthesized by the
condensation of 5,5'-methylenebis(2-hydroxybenzaldehyde) (1) and (1H-benzo[d]imidazol-2-yl)methanamine.HCl salt (2). This Schiff base derivative was
reported for the first time and was fully characterized by FT-IR, UV–vis, 1H-NMR,
13C-NMR and mass spectroscopy. Electronic absorption and
fluorescence titration studies of 3
with different metal cations in a DMF show a highly selective binding affinity
only toward and Zn2+ ion. The crystal
structure of 2, C8H13Cl2N3O,
has been determined by single crystal X-ray
diffraction method. The crystal structure of the title compound, C8H11N32+×2(Cl—)×H2O, consists of an organic 1H-benzoimidazol-3-ium
(C8H11N32+) cation, an inorganic
2(Cl—) anion and one water (H2O) molecule. In the
cation of the title compound, C8H11N32+,
the benzimidazole ring system is planar with a maximum deviation of -0.012
(3) Å. The crystal
belongs to monoclinic system, space group P21/c. The crystal packing is stabilized by intramolecular
N–H···O, N–H···Cl, the intermolecular
N–H···Cl interactions link the molecules into a
two-dimensional network and between anions and the water molecules. π-π contacts between benzimidazole rings
[centroid–centroid distances = 3.4642 (2) Å,
3.5309 (2) Å and 3.5527 (2) Å] may further stabilize the structure.
The Thermal Investigation, Thermokinetic Analysis and Antimicrobial Activity of Two New Energetic Materials Obtained from Nucleophilic Substitution of Nitro Pyridine Ring
Authors: İnal Emine Kübra , Acar Nurcan , Sopacı Şaziye Betül , Yıldız Ceren , Nazır Hasan , Atakol Orhan , Öz Sevi 
Published: December 2018

2-Chloro-3 and 5-dinitropyridine were put into
reaction with hydrazine and 3-aminopyrazole to obtain two new highly
nitrogenous energetic substances. These energetic substances are;
N(3,5-dinitropyridyn-2-yl) hydrazine (I),
and N(3,5-dinitropyridyn-2-yl)3-aminopyrazole (II). These substances were characterized with element analysis,
mass spectroscopy, IR spectroscopy, 1HNMR and 13CNMR
methods. Besides, the substances were analyzed with TG and thermal
decomposition mechanisms were interpreted. Apart from these, isothermal and
thermal kinetic analysis methods were used to reveal out the activation
energies and Arrhenius pre-exponential factors. Thermodynamic parameters of
decomposition reactions were measured by using these values. Nitrofuroxane ring
was concluded to be the sub-product in thermal decomposition reactions.
Gaussian 09 software algorithms were used to measure the standard formation
enthalpy values of the two energetic substances. Using these values, the reaction enthalpy
value of the thermal decomposition reaction according to Hess's law and the
result obtained was compared with the value obtained from the differential
scanning calorimetry method. Experimental and theoretical results were observed
to be similar. In addition to these, antimicrobial effects of the highly
nitrogenous energetic substances were measured for 5 different bacteria and
their antifungal effects were measured for one type of fungus. As they were
highly nitrogenous, the bacteria were found to be using the nitrogen in these
substances for nutritional purpose.
Investigation of Cryptosporidium spp. in Immunosuppressive and Immunocompetent Cases with Diarrhea by Microscopic, Serological and Molecular Methods
Authors: YILMAZ Ahmet , AKKAŞ Önder , GÜVEN Esin , AYDIN Hakan , USLU Hakan 
Published: December 2018

Objective: In this study, our aim was to compare the diagnostic methods with each other and show the presence of Cryptosporidium oocysts by using molecular, serological and microscopic methods in stool samples which were collected from immunosuppressive and immunocompetent patients with diarrheaMethods: Total 172 stool samples were collected from 80 immunosuppressive patients and 92 immunocompetent patients (between 0-94 years) with diarrhea. These stool samples were obtained from the different clinics of Ataturk University, Yakutiye Research Hospital between January 2014 and July 2014. Patient group composed of 49 persons between 0-14 years and 123 persons between 15-94 years. On the other hand, 141 patients were using tap water while 41 of them were using well water. Modified acid-fast staining, ELISA and DFA techniques were applied to detect the Cryptosporidium parasite positivity. Nested PCR method was performed to the samples which were detected positive with one of the above methods.Results: The positivity was detected in 5.8%, 4.1% and 3.5% by ELISA, DFA technique and Modified acid-fast staining method, respectively. Cryptosporidium DNA was detected in only 1.2% by PCR method. The rates of positivity were 6.3% and 5.4% in immunosuppressive and immunocompetent patients, respectively. The positivity was detected in 10.2% and 4.1% in 0-14 age group and 15-94 age group patients, respectively. On the other hand, 4.3% and 12.9% positivity rates were detected in tap water and well water users respectively. Conclusion: Our study pointed out that the investigation of Cryptosporidium oocysts as diarrhea agents in especially immunosuppressive patients, individuals in childhood and well water users may be useful. Because cryptosporidiosis is a common disease in children and immunosuppressive individuals. Additionally, we think that ELISA method can be preferred to other methods in terms of high sensitivity and ease of application.
An insight into design of prefabricated and prestressed concrete monoblock railway ties for service loads
Authors: Bezgin Niyazi Özgür 
Published: December 2018

Ballasted railway track ties support the wheel forces of a train that are transferred by the rails, maintain the track gauge and provide track stability. Prestressed concrete ties provide the required track bearing to the applied wheel loads and constitute a major part of the track self-weight. Design of prestressed concrete ties involves an evaluation of their structural interaction with the ballast and an understanding of prestressed concrete design for service loads and ultimate loads. This paper aims to provide an insight for the design of a prestressed concrete ballasted railway tie under service loads and highlight the genuine qualities of tie design in terms geotechnical engineering, materials engineering and structural engineering. Through the analysis of a finite element model, this paper presents estimations for bending moment values under service conditions for a prestressed concrete high-speed railway tie under varying track support conditions. The paper then compares the estimated values with those suggested by the relevant design guidelines for railway ties.
İŞÇİ SAĞLIĞI VE İŞ GÜVENLİĞİ (İSİG) SİSTEMİNİN İNŞAAT UYGULAMA İŞ PROGRAMINA ENTEGRASYONU
Authors: SEVIM MERVE , Gürcanlı Gürkan Emre 
Published: December 2018

Ölümlü ve ağır yaralanmaların sık yaşandığı
inşaat sektöründe, iş kazaların önüne geçilmesi yönünde atılacak her adım hem can
kayıplarının önlenmesi açısından hem de işgücü ve maddi kayıpların ülke
ekonomisine etkisi açısından çok büyük bir öneme sahiptir. Yalnızca
ülkemizde değil, birçok ülkede iş kazaları ve iş güvenliği sorunlarının bir
türlü kontrol altına alınamamakta ve bu durum bu konunun ele alınması
zorunluluğunu daha da ön plana çıkarmaktadır.

Sektörde yer alan uygulamalara
bakıldığında, sahada en düşük kademede çalışan teknik personelden, yönetici
pozisyonunda çalışan kişilere kadar genel olarak İşçi Sağlığı ve İş Güvenliği
konusunda bilgi eksikliği görülmektedir. Şantiyelerde İSG kontrol ve denetim
mekanizmasının saha ekibinden ayrı olarak yönetilmesi, İSG kontrol ve denetim ekibinin saha
imalatlarından ve iş programından habersiz olması İSG faaliyetlerinin de sahada
plansız olarak yürütülmesine ve dolayısıyla da problemlere ve iş kazalarına
sebep olmaktadır. İSG ekibi ve teknik ekip arasındaki koordinasyon eksikliği
entegre bir sisteme ihtiyacı doğurmaktadır. Bu problemin çözümüne ilişkin
gerçekleştirilen bu çalışmanın amacı, işçi sağlığı ve iş güvenliği (İSİG) yönetim sistemi ile süresel planlama
sistemi arasındaki koordinasyon eksikliğinin giderilmesi amacı ile inşaat yapım
işleri iş programına entegre edilmiş bir işçi sağlığı ve iş güvenliği (İSİG)
bilgi belge sistemi yaratmaktır. ISO 45001 VE ISG iç tüzüğüne ilave olarak odak
grup çalışması yapılarak bir İSİG bilgi belge yönetim sistemi oluşturulmuştur Uygulama
projesine ilişkin iş programı Primavera programı P6 versiyonunda CPM tekniği
kullanılarak hazırlanmış ve ISIG yönetim sistemi içerisinde oluşturulan
aktiviteler, belgeler ve prosedürler; odak gruptaki iş güvenliği uzmanları
desteği ile uygulama inşaat iş programa entegre edilmiştir. Bu çalışma ile saha
ekipleri ile ISG kontrol denetim ekipleri arasındaki koordinasyon eksikliği
probleminin önüne geçilmesi hedeflenmektedir.
Mavi Renklenme Zararının Tomrukların Endüstriyel İşlenme Özellikleri Üzerine Etkileri
Authors: KOMUT Osman , ÖZTÜRK Atakan 
Published: December 2018

Mavi renklenme
tomruk, kereste ve kullanım yerlerindeki malzemede estetik karakteristikler ve
mekanik şok direncinde neden olduğu değişimler dolayısıyla önemli ekonomik
kayıplara yol açmaktadır. Diğer yandan, zarara maruz kalmış malzemede emprenye
ve üst yüzey işlemlerindeki başarı oranının düşük olmasının tomruğun
endüstriyel kullanım alanlarını önemli ölçüde sınırlandırdığı
bilinmektedir. Bu çalışma mavi renklenme
zararının, tomruk işleyen orman endüstri işletmeleri üretim süreci üzerindeki
etkilerini ve neden olduğu kayıpları belirlemeyi amaçlamıştır. Araştırma,
Gümüşhane ilinde Sarıçam tomruğu işleyen toplam 9 küçük ve orta ölçekli kereste
üretim işletmesinde gerçekleştirilmiştir. Çalışmada, mavi renklenme zararının
boyutu tomruk toplam hacmine oranlanarak değerlendirilmiştir. Diğer yandan, inşaat ve doğrama sektörlerine
yönelik üretim gerçekleştiren işletmeler arasında, mavileşme sonucu oluşan
tahribat yönünden karşılaştırmalar yapılmıştır. Çalışma sonucunda, mavi
renklenme tahribatında hacmen zarara maruz kalma oranının diri odun genişliği,
tomruk boy ve çap değişkenlerine bağlı olmak üzere %32-84 arasında değiştiği belirlenmiştir.
Ayrıca, inşaat ve doğrama sektörlerine
yönelik kereste üretimi yapan işletmeler arasında tomruk enine kesit yüzeyindeki
mavileşmiş alan genişliği ve bozuk hacim oranı değişkenlerine göre istatistiksel
düzeyde anlamlı farklılıklar bulunduğu (p&lt;0,05) tespit edilmiştir. Diğer
yandan, inşaat sektörüne yönelik üretim yapan kereste işletmelerinde mavi
renklenme zararının göz ardı edildiği görülmüştür. Doğrama sektörüne yönelik
üretim yapan işletmelerde ise malzemenin görsel niteliklerinin iyileştirilmesi
amacıyla mavileşmiş kısmın uzaklaştırıldığı, ancak bu işlem dolayısıyla ilave enerji
ve işgücü maliyetlerinin oluştuğu tespit edilmiştir.
Metode Moment Invariant Geometrik untuk Menganalisis Jenis Daging Babi dan Daging Sapi
Authors: Nurhayati Oky Dwi , Hastuti Isti Pudji 
Published: December 2018

Beef needs have increased every year. So as the need for expensive beef even at certain times tends to rise. This is used by cheat seller to mix beef with pork because pork is relatively cheaper. This is very detrimental to consumers. Visually, many peoples (consumers) couldn’t distinguish these two types of meat. Hence, we conduct research to distinguish both types of meat. One way to overcome these problems is the use of complete image processing techniques. The aim of this research was establised an application prototype to distinguish beef and pork with image processing techniques. Image processing method is used to distinguish the types of meat done by pre-processing, segmentation, feature extraction with geometrical moment invariant and K-NN classification. Geometric moment invariant method proposed to analyze beef and pork is done by extracting unique values from each images. This method can be used as a description of the form based on the moment theory. The results showed that the image processing method and K-NN classification with a value of k = 3 used in the research could significantly used to analyze the type of meat namely beef and pork. The other difference can be shown from the phi moment invariant value, especially the value of phi (1) and phi (2)
Adsorption mechanism of dichlorvos onto coconut fibre biochar: the significant dependence of H-bonding and the pore-filling mechanism
Authors: Binh Quach An , Kajitvichyanukul Puangrat 
Published: December 2018

Abstract
The adsorption mechanism of dichlorvos onto coconut fibre biochar (CFB) was investigated by the batch adsorption technique. Coconut fibre waste material was synthesised at 600 °C for 4 h under oxygen-limited conditions. The biochar was modified by HCl acid to enhance the specific surface area and porosity. The characteristics of the biochar were analysed by scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) specific surface area, and Fourier transform-infrared (FT-IR). The results showed that the BET speciﬁc surface area of biochar was 402.4 m2/g. Experimental data presented a good fit to Langmuir isotherm and the pseudo-second-order model. Langmuir isotherm illustrated that monolayer adsorption of dichlorvos occurred on the surface of CFB, with a maximum adsorption capacity of 90.9 mg/g. The diffusion model confirmed that the liquid film diffusion was the rate-limiting step, and the major diffusion mechanism of dichlorvos onto biochar. The BET result after dichlorvos adsorption demonstrated that pore-filling occurred and occupied 58.27%. The pore-filling and chemical interactions, performed important roles in the adsorption of dichlorvos onto CFB. Chemical adsorption is comprised of two interactions, which are hydrophobic and H-bonding, but the prime is H-bonding. CFB is a very potential material for the removal of dichlorvos and environmental pollutants.
Why Should Psychiatrists and Neuroscientists Worry about Paraoxonase 1?
Authors: Moreira Estefania Gastaldello , Boll Karine Maria , Correia Dalmo Guilherme , Soares Janaina Favaro , Rigobello Camila , Maes Michael 
Published: December 2018

Background:
Nitro-oxidative stress (NOS) has been implicated in the pathophysiology
of psychiatric disorders. The activity of the polymorphic antioxidant enzyme paraoxonase 1 (PON1)
is altered in diseases where NOS is involved. PON1 activity may be estimated using different substrates
some of which are influenced by PON1 polymorphisms.

Objectives:
1) to review the association between PON1 activities and psychiatric diseases using a
standardized PON1 substrate terminology in order to offer a state-of-the-art review; and 2) to review
the efficacy of different strategies (nutrition, drugs, lifestyle) to enhance PON1 activities.

Methods:
The PubMed database was searched using the terms paraoxonase 1 and psychiatric diseases.
Moreover, the database was also searched for clinical trials investigating strategies to enhance
PON1 activity.

Results:
The studies support decreased PON1 activity as determined using phenylacetate (i.e.,
arylesterase or AREase) as a substrate, in depression, bipolar disorder, generalized anxiety disorder
(GAD) and schizophrenia, especially in antipsychotic-free patients. PON1 activity as determined
with paraoxon (i.e., POase activity) yields more controversial results, which can be explained by the
lack of adjustment for the Q192R polymorphism. The few clinical trials investigating the influence
of nutritional, lifestyle and drugs on PON1 activities in the general population suggest that some
polyphenols, oleic acid, Mediterranean diet, no smoking, being physically active and statins may be
effective strategies that increase PON1 activity.

Conclusion:
Lowered PON1 activities appear to be a key component in the ongoing NOS processes
that accompany affective disorders, GAD and schizophrenia. Treatments increasing attenuated
PON1 activity could possibly be new drug targets for treating these disorders.
Mechanical and Electromagnetic Analysis of High Speed Motor/Generator for Electric Turbo Compounding System
Authors: Choi Bongseok , Jung Donghoon , Lee Jaek wang , Lee Ju 
Published: December 2018

Background:
Recently, environment friendly technologies are being introduced as global warming is rapidly progressing. One of the effective way to reduce the problem, Electric Turbo Compounding System has been researched globally. With this system, about 30% exhaust gas can be recycled as a power source. Therefore, this system is effective for engine systems with purposes such as downsizing and increasing efficiency of the system.

Objective & Method:
Surface mounted Permanent Magnet Motor is applied to this system due to its high efficiency, power density, small size, and low weight. However, during high speed operation, a retaining sleeve is essential in rotor such as Inconel 718 to satisfy a mechanical safety factor of the rotor. In this paper, through basic theory, the sleeve thickness is predicted according to the permanent magnet dimension and minimum sleeve thickness is determined satisfying mechanical safety factor by mechanical analysis. Furthermore, by electromagnetic analysis output characteristics according to the permanent magnet dimension having same constraints such as volume, current density, current and flux distribution are compared.

Result & Conclusion:
Based on the results of the electromagnetic analysis and mechanical analysis, the appropriate ratio of electric and magnetic loading is determined with equivalent constraint condition. Consequently, only model 2 satisfies the requirement at rated and maximum speed within the current limit.
Spatial Correlation of Cone Tip Resistance for Soil in Nasiriyah
Authors: Shakir Ressol R. 
Published: December 2018

Background:Quantification of soil property spatial variations is an important step in any reliability-based design. Little stochastic parameter information about the soil in Nasiriyah, which is in southern Iraq, is available.Methods:In this paper, the Scale Of Fluctuation (SOF) for the site soil is examined, which is suggested for construction of the refinery fuel station project as no random parametric quantity has been studied in this region. A Cone Penetration Test (CPT) was performed as part of the site investigation to a depth of 20 m in the vertical direction, and 24 CPTs were analyzed within the site. The spatial correlation was computed using four methods, including Single Exponent (SNE), Square Exponent (SQE), Cosine Exponent (CSE) and Second-Order Markov (SOM). Identification of the soil type depended on the most recent classification chart, which is based on CPT results. The spatial correlation was evaluated for the vertical direction considering the cone tip resistance (qc) component. Three trend functions were applied to all CPT soundings, including linear, quadratic and cubic polynomials, which were utilized to transform the non-stationary data to stationary data. Three modes of soil were employed, including the eight-meter soil layer, a twelve-meter soil layer and the entire twenty meters of soil, which includes both layers.Results and Discussion:The mean values of SOF were 0.54 m, 0.53 m, and 1.73 m for soil layers 8 m, 12 m, and 20 m, respectively. The high value of the last mean is attributed to the 20 m of stratification in the ground. This study also indicates that the SOF decreases as the polynomial degree increases, which is due to enhanced fitting. The coefficient of variation (COV) for the SOF shows little variability for most of the studied soil cases.