bluuebunny/crossref_metadata_2025_split huggingface dataset:
UAV–LiDAR accuracy in vegetated terrain
Authors: Kucharczyk Maja , Hugenholtz Chris H. , Zou Xueyang 
Published: August 2018

We examined the horizontal and vertical accuracy of LiDAR data acquired from an unmanned aerial vehicle (UAV) at a field site with six vegetation types: coniferous trees, deciduous trees, short grass (0–0.3 m height), tall grass (>0.3 m height), short shrubs (0–1 m height), and tall shrubs (>1 m height). The objective was to assess positional accuracy of the ground surface in the context of digital mapping standards, and to determine how different vegetation types affect vertical accuracy. The data were acquired from a single-rotor vertical takeoff and landing UAV equipped with a Riegl VUX-1UAV laser scanner, KVH Industries 1750 IMU, and dual NovAtel GNSS receivers. Reference measurements of ground surface elevation were acquired with conventional field surveying techniques. Accuracy was evaluated using methods in the 2015 American Society for Photogrammetry and Remote Sensing (ASPRS) Positional Accuracy Standards for Digital Geospatial Data. Results show that horizontal accuracy and vegetated vertical accuracy at the 95% confidence level were 0.05 and 0.24 m, respectively. Median vertical errors significantly differed among 10 of 15 vegetation type pairs, highlighting the need to account for variations of vegetation structure. According to the 2015 ASPRS standards, the reported errors fulfill the requirements for mapping at the 2 and 8 cm horizontal and vertical class levels, respectively.
Salt Intake and All-Cause Mortality in Hemodialysis Patients
Authors: Ikenoue Tatsuyoshi , Koike Kiyomi , Fukuma Shingo , Ogata Satoshi , Iseki Kunitoshi , Fukuhara Shunichi 
Published: August 2018

<b><i>Background:</i></b> Although some clinical practice guidelines regarding hemodialysis recommend salt restriction, few studies have examined the association between salt intake and clinical outcomes in hemodialysis patients. This study aimed to clarify the association between salt intake and mortality in hemodialysis patients. <b><i>Methods:</i></b> This retrospective cohort study was based on the Japanese Society for Dialysis Therapy renal data registry database (2008) and included 88,115 adult patients who had received hemodialysis for at least 2 years. Estimated salt intake was the main predictor and was calculated from intra-dialytic weight loss and pre- and post-dialysis serum sodium levels. Nonlinear logistic regression was used to determine the association between salt intake and mortality, adjusting for potential confounders. The outcomes considered were all-cause mortality and cardiovascular death at 1 year. <b><i>Results:</i></b> The median (25–75th percentile) salt intake at baseline was 6.4 (4.6–8.3) g/day. At 1 year, all-cause mortality occurred in 1,845 (2.1%) patients, including 807 cardiovascular deaths. The low salt intake group (&#x3c; 6 g/day) demonstrated the highest all-cause mortality and cardiovascular deaths. No association was observed between high salt intake, all-cause mortality and cardiovascular deaths. The lowest risk for all-cause mortality and cardiovascular death occurred among patients with an estimated salt intake of 9 g/day. <b><i>Conclusion:</i></b> Low salt intake, but not high salt intake, was associated with all-cause and cardiovascular mortality in Japanese hemodialysis patients. Further studies to justify including a lower limit of salt intake for hemodialysis patients are suggested.
Feminism Against Crime Control: On Sexual Subordination and State Apologism
Authors: Duff Koshka 
Published: August 2018

AbstractIts critics call it ‘feminism-as-crime-control’, or ‘Governance Feminism’, diagnosing it as a pernicious form of identity politics. Its advocates call it taking sexual violence seriously – by which they mean wielding the power of the state to ‘punish perpetrators’ and ‘protect vulnerable women’. Both sides agree that this approach follows from the radical feminist analysis of sexual violence most strikingly formulated by Catharine MacKinnon. The aim of this paper is to rethink the Governance Feminism debate by questioning this common presupposition. I ask whether taking MacKinnon’s analysis of sexual violence seriously might, in fact, itself give us reason to be critical of political strategies that embrace the punitive state. By raising this question, I hope to persuade radical feminists to listen to critics of carceral politics rather than dismissing them as rape apologists, and critics of carceral politics to listen to radical feminists rather than dismissing them as state apologists.
Social Networks and Social Worlds
Authors: Hardesty Jared Ross 
Published: August 2018

Abstract
This essay argues that the “slave community” paradigm obfuscates alternative lived experiences for enslaved men and women, especially those living in the urban areas of the early modern Atlantic world, and uses eighteenth-century Boston as a case study. A bustling Atlantic port city where slaves comprised between ten and fifteen percent of the population, Boston provides an important counterpoint. Slaves were a minority of residents, lived in households with few other people of African descent, worked with laborers from across the socio-economic spectrum, and had near constant interaction with their masters. Moreover, slavery in Boston reached its zenith before the American Revolution, meaning older, pre-revolutionary and early modern notions of social order—hierarchy, deference, and dependence—structured their society and everyday lives. These factors imbricated enslaved Bostonians in the broader society. Boston’s slaves inhabited multiple “social worlds” where they fostered a rich tapestry of relations and forms of resistance.
Observation-Informed Generalized Hybrid Error Covariance Models
Authors: Satterfield Elizabeth A. , Hodyss Daniel , Kuhl David D. , Bishop Craig H. 
Published: August 2018

AbstractBecause of imperfections in ensemble data assimilation schemes, one cannot assume that the ensemble-derived covariance matrix is equal to the true error covariance matrix. Here, we describe a simple and intuitively compelling method to fit calibration functions of the ensemble sample variance to the mean of the distribution of true error variances, given an ensemble estimate. We demonstrate that the use of such calibration functions is consistent with theory showing that, when sampling error in the prior variance estimate is considered, the gain that minimizes the posterior error variance uses the expected true prior variance, given an ensemble sample variance. Once the calibration function has been fitted, it can be combined with ensemble-based and climatologically based error correlation information to obtain a generalized hybrid error covariance model. When the calibration function is chosen to be a linear function of the ensemble variance, the generalized hybrid error covariance model is the widely used linear hybrid consisting of a weighted sum of a climatological and an ensemble-based forecast error covariance matrix. However, when the calibration function is chosen to be, say, a cubic function of the ensemble sample variance, the generalized hybrid error covariance model is a nonlinear function of the ensemble estimate. We consider idealized univariate data assimilation and multivariate cycling ensemble data assimilation to demonstrate that the generalized hybrid error covariance model closely approximates the optimal weights found through computationally expensive tuning in the linear case and, in the nonlinear case, outperforms any plausible linear model.
Observations and Predictability of a Nondeveloping Tropical Disturbance over the Eastern Atlantic
Authors: Brammer Alan , Thorncroft Chris D. , Dunion Jason P. 
Published: August 2018

Abstract
A strong African easterly wave (AEW) left the West African coast in early September 2014 and operational global numerical forecasts suggested a potential for rapid tropical cyclogenesis of this disturbance in the eastern Atlantic, despite the presence of a large region of dry air northwest of the disturbance. Analysis and in situ observations show that after leaving the coast, the closed circulation associated with the AEW trough was not well aligned vertically, and therefore, low-level or midlevel dry air was advected below or above, respectively, areas of closed circulation. GPS dropwindsonde observations highlight the dry air undercutting the midlevel recirculation region in the southwestern quadrant. This advection of dry air constrains the spatial extent of deep convection within the AEW trough, leading to the vortex decaying. As the column continues to be displaced horizontally, losing vertical alignment, this enables increased horizontal advection of dry air into the system further limiting convective activity. Ensemble forecasts indicate that short-term errors in precipitation rate and vorticity generation can lead to an over intensified and well-aligned vortex, which then interacts less with the unfavorable environment, allowing for further convection and intensification. The stronger vortex provides more favorable conditions for precipitation through a more vertically coherent closed circulation and thus a positive feedback loop is initiated. The short-term forecasts of precipitation were shown to be sensitive to lower-tropospheric moisture anomalies around the AEW trough through ensemble sensitivity analysis from Global Ensemble Forecast System real-time forecasts.
Protecting Walnut Orchards against Frost: A Test of Extended Theory of Planned Behavior
Authors: Kazemi Neda , Sharifzadeh Maryam , Ahmadvand Mostafa 
Published: August 2018

Abstract
Cold stress is a major environmental constraint that limits nut productivity worldwide. Late spring frost is identified as a yield-reducing factor in Persian walnut production as well. Despite significant improvements in cold and freezing tolerance methods, orchardists have not taken advantage of these recommended protection methods. This study examined determinants of walnut orchardists’ frost-protection behavior, using the extended theory of planned behavior (TPB) as a conceptual framework. Based on TPB assumptions, frost-protection behavior is mediated by a series of constructs. The purpose of this research was to examine the role of TPB variables (extended by orchard-system profile) in meeting the necessities of performing active and passive methods of frost protection. A total of 91 orchardists completed a baseline questionnaire that included the TPB constructs. The present investigation was carried out in the major walnut growing site of Sepidan County, western Fars Province, Iran. The results from the hierarchical multiple regression showed that the behavioral attitude, perceived behavioral control (PBC), intention, orchard-system profile, and interaction of orchard-system features and PBC were significant predictors of frost-protection behavior in the prospective sample. Results of the present study provided evidence that the extended TPB is a useful framework for understanding orchardists’ frost-protection behavior.
Patient-Reported Outcomes Within the First Year After Hip Arthroscopy and Rehabilitation for Femoroacetabular Impingement and/or Labral Injury: The Difference Between Getting Better and Getting Back to Normal
Authors: Thorborg Kristian , Kraemer Otto , Madsen Anne-Dorthe , Hölmich Per 
Published: August 2018

Background: The Copenhagen Hip and Groin Outcome Score (HAGOS) was recently found valid, reliable, and responsive for patients undergoing hip arthroscopy. However, it is currently unknown to what degree patients undergoing hip arthroscopy improve and/or normalize their HAGOS result within the first year after surgery. Purpose: First, to use HAGOS to evaluate clinical outcomes at 3, 6, and 12 months after hip arthroscopy for femoroacetabular impingement (FAI) and/or labral injury and compare the HAGOS results with the modified Harris Hip Score (mHHS). Second, to explore how many patients would (a) improve to a degree of minimal clinical importance (MIC) and (b) obtain scores within the reference intervals of healthy controls. Study Design: Cohort study; Level of evidence, 2. Methods: From September 2011 to March 2014, 97 consecutive patients [56 females (mean age, 38 years; range, 17-60 years) and 41 males (mean age, 37 years; range, 19-59 years)] underwent first-time hip arthroscopy for FAI and/or labral injury. Standardized postoperative rehabilitation instructions were provided. HAGOS (0-100 points) and mHHS (0-100 points) values were obtained preoperatively and again postoperatively at 3, 6, and 12 months. Furthermore, 158 healthy controls, matched on age and sex, were included to obtain HAGOS and mHHS reference values for comparison. Minimal important change was determined by using the 0.5 SD of the baseline values for HAGOS and mHHS. Results: Improvements for all HAGOS subscales and mHHS results were seen at 3 months ( P < .001). Further improvements were seen only for HAGOS Sport and Recreation (Sport/Rec) and Participation in Physical Activities (PA) subscales between 3 and 12 months ( P < .05) but not for HAGOS Pain, Symptoms, Activities of Daily Living (ADL), or Hip-Related Quality of Life (QOL) subscales or the mHHS. Furthermore, on HAGOS Sport/Rec, PA, and QOL subscales, patients reached scores of only 54 to 70 points 1 year after surgery. At the individual level, up to 70% of the patients experienced minimal important improvements during the first year after surgery, but only up to 38% and 36% of patients reached a score within the reference interval of HAGOS and mHHS, respectively. Conclusion: Statistically and clinically relevant improvements in HAGOS and mHHS results after hip arthroscopy and rehabilitation can be seen at 3 months and up to 1 year. However, specific HAGOS subscales suggest that a patient’s ability to function and participate in sport and physical activity is still markedly reduced 1 year after surgery. Furthermore, the majority of patients undergoing hip arthroscopy cannot expect to reach the level of the healthy population on self-reported pain and function within the first year after surgery.
Methods for determination of stagnation in pneumatic ventricular assist devices
Authors: Obidowski Damian , Reorowicz Piotr , Witkowski Dariusz , Sobczak Krzysztof , Jóźwik Krzysztof 
Published: August 2018

Background: A pneumatic paediatric ventricular assist device developed at the Foundation of Cardiac Surgery Development, Zabrze, equipped with valves based on J. Moll’s design, with later modifications introduced at the Institute of Turbomachinery, Lodz University of Technology, was tested numerically and experimentally. The main aim of those investigations was to detect stagnation zones within the ventricular assist device and indicate advantages and limitations of both approaches. Methods: In the numerical transient test, a motion of the diaphragm and discs was simulated. Two different methods were used to illustrate stagnation zones in the ventricular assist device. The flow pattern inside the chamber was represented by velocity contours and vectors to validate the results using images obtained in the laser particle image velocimetry experiment. Results: The experimental light-based method implied problems with proper illumination of regions in the wall vicinity. High-resolution flow data and other important parameters as stagnation regions or flow patterns in regions not accessible for light in the particle image velocimetry method are derived in the numerical solution. However, computations of a single case are much more time-consuming if compared to a single experiment conducted on a well-calibrated stand. Conclusion: The resulting main vortexes in the central part of the pump chamber and the velocity magnitudes are correlated in both methods, which are complementary and when used together offer better insight into the flow structure inside the ventricular assist device and enable a deeper analysis of the results.
Video capsule endoscopy is safe and effective in suspected small bowel bleeding among left ventricular assist device recipients
Authors: Itskoviz David , Ben Avraham Ben , Banai Hagar , Avni Irit , Ben Gal Tuvia , Dotan Iris , Gal Eyal 
Published: August 2018

Introduction: Suspected small bowel bleeding is frequently encountered in left ventricular assist device recipients and the identification of the culprit lesion may be challenging. Data regarding the safety and yield of small bowel capsule in the investigation of suspected small bowel bleeding are limited. We aimed to evaluate the safety and efficacy of small bowel video capsule endoscopy for the investigation of suspected small bowel bleeding among left ventricular assist device recipients. Methods: Patients with left ventricular assist device who underwent video capsule endoscopy for the investigation of suspected small bowel bleeding were identified. Suspected small bowel bleeding was defined as the presence of overt bleeding at least 30 days following left ventricular assist device implantation with no identifiable cause in upper and lower endoscopy. Results: A total of 10 patients with left ventricular assist device associated suspected small bowel bleeding performed 12 small bowel capsule endoscopies between January 2008 and December 2015 at our tertiary medical care facility. There were no cases of capsule retention or any other serious adverse events during the exams. A significant finding was identified in 8 out of 10 patients, including 3 cases of small bowel angioectasia, 2 cases of small bowel ulcers, 1 case of cecal polyp, and 2 cases of active bleeding with no apparent bleeding source. Small bowel enteroscopy identified and treated bleeding angioectasia in the latter two cases. Conclusion: Small bowel capsule endoscopy is safe and effective in the investigation of left ventricular assist device associated suspected small bowel bleeding.
Late neurological deficit after attempted PICC insertion in the arm
Authors: Antunes Bruno FF , Machado Andrea MN , Miziara Roberta A , Liao Adolfo W , Mendes Cynthia A , Wolosker Nelson , Teivelis Marcelo P 
Published: August 2018

Introduction: Insertion of central catheters in peripheral vessels is a common procedure performed for a variety of indications, including parenteral nutrition. Hyperemesis gravidarum may require parenteral nutrition in exceptional situations. Although globally safe, insertion of peripherally inserted central catheters (PICCs) can lead to complications. Case Report: We describe a case of a pregnant woman who required parenteral nutrition and underwent an unsuccessful PICC insertion attempt resulting in arterial puncture, and who 34 days later presented with right upper limb paresthesia. A pseudoaneurysm with nerve compression was diagnosed and treated by open surgery, without maternal or fetal complications. Conclusion: We recommend active surveillance ultrasound (e.g. in the first 24–48 h) of unsuccessful PICC insertion attempts, because late complications may occur and require invasive procedures for treatment.
Characteristics of Sinus Fungus Ball: A Unique Form of Rhinosinusitis
Authors: Jiang Rong-San , Huang Wan-Chun , Liang Kai-Li 
Published: August 2018

Objective: The purpose of this study was to investigate the characteristics of this unique form of rhinosinusitis. Methods: Ninety-one patients with sinus fungus balls were evaluated for clinical characteristics. Nasal tissues obtained from 38 patients with sinus fungus ball, along with 26 controls were used for histopathological, cytokines/chemokines, western blotting, and genetic analyses. Results: Patients with fungus balls had significantly more females and their age was older. The presentation of fungus ball was predominantly unilateral (97.8%). Thirty-three patients (36.3%) had risk factors for fungal infection. Macrophage and neutrophil dominated cellular infiltration was found in nasal tissues of fungus ball patients. A tendency of reduced tight junction staining (e-cadherin) and protein expression was found. Interleukin 8 (IL8) and granulocyte colony stimulating factor (G-CSF) significantly increased in sinus fungus ball tissue homogenates when compared with those from controls. Higher prevalence of a single single nucleotide polymorphism (SNP) with E-cadherin was found in the patients with fungus ball. Conclusions: We found that patients with sinus fungus ball had robust immune responses, allowing recruitment and activation of macrophages and neutrophils. However, patients with sinus fungus ball could have genetic or acquired weakness in immunity. The fungal hyphae were localized and accumulated within single sinus instead of being eradicated by host.
Nearest Neighbor Method to Estimate Internal Target for Real-Time Tumor Tracking
Authors: Zhang Jie , Huang Xiaolin , Shen Yuxiaotong , Chen Ying , Cai Jing , Ge Yun 
Published: August 2018

Purpose: This work proposed a nearest neighbor estimation method to track the respiration-induced tumor motion. Methods: Based on the simultaneously collected motion traces of external surrogate and internal target during the modeling phase prior to treatment, we first obtain the nearest neighbors of the current surrogate in external space. Subsequently, the concurrent targets in internal space are determined and used to estimate the current target position. The method was validated on 71 cases that were from 3 open access databases. In addition, to evaluate the method’s estimation and prediction accuracy, we compared the method with other works. Results: Except for 2 cases, the nearest neighbor estimation achieved the root-mean-square error of <3 mm. The comparison indicated that the method had better estimation accuracy than polynomial model and good prediction performance. Discussion: The 2 exceptive cases were further analyzed for failure causes. We inferred that one was because of the lack of estimating new target in our method, and the other one was because of the mistake during data collection. Accordingly, the potential solutions were suggested. Besides, the method’s estimation for surrogate outliers, effects of modeling length, calibration, and extension were discussed. Conclusion: The results demonstrated nearest neighbor estimation’s effectiveness. Except for this, the method imposes no restrictions on the modality of the pretreatment target images and does not assume a specific correspondence function between the surrogate and the target. With only 1 critical parameter, this nearest neighbor estimation method is easy to implement in clinical setting and thus has potential for broad applications.
The surge in biosimilars: considerations for effective pharmacovigilance and EU regulation
Authors: Calvo Begoña , Martinez-Gorostiaga Javier , Echevarria Enrique 
Published: August 2018

The development of biosimilars is growing rapidly, especially in Europe. They are a cost-effective alternative to original biological medicines and can help improve patient access to these therapies. The European Medicines Agency (EMA) has been the first to issue scientific guidelines related to regulatory requirements for the approval of biosimilars. These guidelines have been being updated in line with advances in analytical techniques and growing experience in the clinical use of these drugs. Given the complex nature of biological medicines, they pose a greater potential risk of immunogenicity than nonbiological medicines, and hence warrant special consideration. The risk management plan for biopharmaceuticals (innovator and biosimilar drugs) should be based on strengthening ongoing pharmacovigilance activities, especially in the post-approval period. This paper addresses regulatory issues related to the approval of biosimilars in Europe associated with safety considerations linked to the development and use of these medicines. We also discuss the issues of immunogenicity, interchangeability and traceability of biological medicines.