bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping lithological boundaries in mines with array seismology and in situ acoustic emission monitoring
Authors: Pisconti Angelo , Plenkers Katrin , Philipp Joachim , Thomas Christine 
Published: October 2019

SUMMARYKnowledge of the position of lithological boundaries is key information for a realistic interpretation of geological settings. Especially in the mining environment, the exact knowledge of geometrical boundaries and characteristics of rock structures has a great impact for both economic decisions and safety awareness. For this purpose, we investigate the P-coda of high frequency acoustic emission (AE) events (picoseismicity) and test the application of array seismology techniques, usually used to study the Earth's deep interior, on a much smaller scale in a mining environment. In total 52 events were used, all of them recorded in the Asse II salt mine in Lower Saxony (Germany) using a network of 16 piezoelectric sensors. Many of these events show a pulse-like arrival in the late P-coda, suggesting the presence of a well-defined structure which scatters seismic energy. To explore the directional information of the signals in the seismograms we use the sliding-window slowness-backazimuth analysis, performed on the waveform envelope of the entire recording. Strong direct P-wave arrivals are clearly visible with observed slowness and backazimuth as expected for a homogenous medium. This implies straight ray paths from event to sensors indicating that the medium between the events and the sensors is homogeneous for wavelengths larger than about 60 cm. In the late P-coda we observe out-of-plane arrivals from southeast and, assuming single P-to-P scattering, we find that the scatterers responsible for these observations are clustered in space defining a sharp reflector corresponding to a known lithological boundary located at the southern flank of the salt dome. In agreement with the established geological model we observe no other dominant reflections in the analysed waveforms that would indicate previously unknown lithological boundaries. This study shows that array seismology can be applied to AEs in mines to gain more information on structures and heterogeneities located in the vicinity of the monitored rock volume. In micro-acoustically monitored mines, this technique could be a valuable addition to increase hazard awareness and mining efficiency at little or no extra costs.
Crustal structure variations in south-central Mexico from receiver functions
Authors: Rodríguez-Domínguez Miguel , Pérez-Campos Xyoli , Montealegre-Cázares Conrado , Clayton Robert W , Cabral-Cano Enrique 
Published: October 2019

SummaryMexico has a complex geological history that is typified by the distinctive terranes that are found in the south-central region. Crustal thickness variations often correlate with geological terranes that have been altered by several processes in the past, for example aerial or subduction erosion, underplating volcanic material or rifting but few geophysical studies have locally imaged the entire continental crust in Mexico. In this paper, the thickness of three layers of the crust in south-central Mexico is determined. To do this, we use P- and S-wave receiver functions (RF) from 159 seismological broad-band stations. Thanks to its adaptive nature, we use an empirical mode decomposition (EMD) algorithm to reconstruct the RFs into intrinsic mode functions (IMF) in order to enhance the pulses related to internal discontinuities within the crust. To inspect possible lateral variations, the RFs are grouped into quadrants of 90°, and their amplitudes are mapped into the thickness assuming a three-layer model. Using this approach, we identify a shallow sedimentary layer with a thickness in the range of 1–4 km. The upper-crust was estimated to be of a few kilometers (&lt;10 km) thick near the Pacific coast, and thicker, approximately 15 km in central Oaxaca and under the Trans-Mexican Volcanic Belt (TMVB). Close to the Pacific coast, we infer a thin crust of approximately 16 ± 0.9 km, while in central Oaxaca and beneath the TMVB, we observe a thicker crust ranging between 30 and 50 km ± 2.0 km. We observe a crustal thinning, of approximately 6 km, from central Oaxaca (37 ± 1.9 km) towards the Gulf of Mexico, under the Veracruz Basin, where we estimate a crustal thickness of 31.6 ± 1.9 km. The boundary between the upper and lower crust in comparison with the surface of the Moho do not show significant variations other than the depth difference. We observe small crustal variations across the different terranes on the study area, with the thinnest crust located at the Pacific coast and Gulf of Mexico coast. The thickest crust is estimated to be in central Oaxaca and beneath the TMVB.
Delivering on the European Pillar of Social Rights: The New Directive on Transparent and Predictable Working Conditions in the European Union
Authors: Bednarowicz Bartłomiej 
Published: October 2019

Abstract
Chapter II of the European Pillar of Social Rights envisages fair working conditions that are further spelled out in two principles on secure and adaptable employment (Principle 5) and information about employment conditions and protection in dismissals (Principle 7). In order to deliver on this framework, in December 2017 the European Commission presented an ambitious and far-reaching proposal for a Directive on transparent and predictable working conditions in the European Union that would repeal Directive 91/533/EC on an employer’s obligation to inform employees of the conditions applicable to the contract or employment relationship. The proposal, after a series of uneasy negotiations in the Parliament and the Council, and with substantial modifications, was subsequently adopted in June 2019. Against this background, the main aim of this note is to analyse the new Directive (EU) 2019/1152. This piece focuses firstly on the Directive’s nuanced hybrid personal ambit of application. Secondly, it examines its material scope of application and sheds some light on the new set of rights and entitlements available to workers, including novel enforcement mechanisms. Finally, the note provides a critical assessment of the Directive with the aim of unveiling its potential to boost workers’ rights in the European Union, in particular those engaged in non-standard forms of employment, who are especially prone to experiencing precarious working conditions, such as on-demand and platform workers.
Whose Autonomy is it Anyway? Freedom of Contract, the Right to Work and the General Principles of EU Law
Authors: O’Connor Niall 
Published: September 2019

Abstract
Just how significant is the freedom of contract found in Article 16 of the EU Charter of Fundamental Rights for the regulation of the employment relationship? For the first half of its existence, few could have foreseen that Article 16 would soon be at the centre of debates surrounding the place of business freedoms within EU employment law. This has changed in the wake of a number of controversial decisions in which the Court of Justice of the EU relied on Article 16 to undermine the effectiveness of employee-protective legislation. The article begins by setting out the nature of freedom of contract in EU law and its effects in the employment context. This is followed by a consideration of the relationship between the general principles and the Charter. Critical Legal Studies is relied on to show that existing arguments as to the use of Article 16 as a radical tool in the employment context have been both exaggerated and underplayed. Finally, potential counterweights to freedom of contract are examined, notably the right to work as both a general principle and Charter right.
Advances in the Development of Therapeutics for Cytomegalovirus Infections
Authors: Acosta Edward , Bowlin Terry , Brooks Jennifer , Chiang Lillian , Hussein Islam , Kimberlin David , Kauvar Lawrence M , Leavitt Randi , Prichard Mark , Whitley Richard 
Published: September 2019

AbstractThe development of therapeutics for cytomegalovirus (CMV) infections, while progressing, has not matched the pace of new treatments of human immunodeficiency virus (HIV) infections; nevertheless, recent developments in the treatment of CMV infections have resulted in improved human health and perhaps will encourage the development of new therapeutic approaches. First, the deployment of ganciclovir and valganciclovir for both the prevention and treatment of CMV infections and disease in transplant recipients has been further improved with the licensure of the efficacious and less toxic letermovir. Regardless, late-onset CMV disease, specifically pneumonia, remains problematic. Second, the treatment of congenital CMV infections with valganciclovir has beneficially improved both hearing and neurologic outcomes, both fundamental advances for these children. In these pediatric studies, viral load was decreased but not eliminated. Thus, an important lesson learned from studies in both populations is the need for new antiviral agents and the necessity for combination therapies as has been shown to be beneficial in the treatment of HIV infections, among others. The development of monoclonal antibodies, sirtuins, and cyclopropovir may provide new treatment options.
Isolation and Molecular Characterization of Tick-Borne Relapsing Fever Borrelia Infecting Ornithodoros (Pavlovskyella) verrucosus Ticks Collected in Ukraine
Authors: Filatov Serhii , Krishnavajhala Aparna , Armstrong Brittany A , Kneubehl Alexander R , Nieto Nathan C , Pérez De León Adalberto A , Lopez Job E 
Published: September 2019

Abstract

Background
Tick-borne relapsing fever (TBRF) is a neglected zoonotic bacterial disease known to occur on 5 continents. We report a laboratory-acquired case of TBRF caused by Borrelia caucasica, which is endemic in Ukraine and transmitted by Ornithodoros verrucosus ticks.

Methods
We isolated spirochetes and characterized them by partially sequencing the 16s ribosomal ribonucleic acid (rrs), flagellin (flaB), and deoxyribonucleic acid gyrase (gyrB) genes and conducting a phylogenetic analysis.

Results
These analyses revealed a close relationship of Ukrainian spirochetes with the Asian TBRF species, Borrelia persica. The taxonomic and nomenclature problems related to insufficient knowledge on the spirochetes and their vectors in the region are discussed.

Conclusions
Although these findings enhance our understanding of species identities for TBRF Borrelia in Eurasia, further work is required to address the neglected status of TBRF in this part of the world. Public health practitioners should consider TBRF and include the disease into differential diagnosis of febrile illnesses with unknown etiology.
Host-Specific Restriction of Avian Influenza Virus Caused by Differential Dynamics of ANP32 Family Members
Authors: Park Young Hyun , Chungu Kelly , Lee Su Bin , Woo Seung Je , Cho Ho Yeon , Lee Hong Jo , Rengaraj Deivendran , Lee Ji-Ho , Song Chang-Seon , Lim Jeong Mook , Han Jae Yong 
Published: October 2019

AbstractBackgroundInfluenza viruses must utilize host factors to complete their lifecycle. Species-specific differences in host factors between birds and mammals mean that avian influenza viruses (AIVs) replicate well in avian hosts but not in human hosts. Acidic nuclear phosphoprotein 32 family member A (ANP32A) has been identified as the host restriction factor for the viral polymerase (vPol) activity of AIVs. The ANP32A belongs to the conserved ANP32 family, the functional roles of which during viral replication remain unclear.MethodsIn this study, we targeted chicken ANP32A using clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-mediated genome editing to examine the functional roles of ANP32A and other members of the ANP32 family.ResultsWe showed that chicken ANP32A only, not ANP32B and ANP32E, plays a pivotal role in supporting vPol activity of AIVs. Furthermore, we found that the human ANP32C, ANP32D, and ANP32E have suppressive effects on vPol activity in contrast to human ANP32A and ANP32B.ConclusionsChicken and human ANP32 family members had different effects on vPol activity, suggesting that species-specific vPol activity of AIVs could be caused by the differential functions and overall competency of ANP32 family members.
Uncovering the relationship between food-related discussion on Twitter and neighborhood characteristics
Authors: Vydiswaran V G Vinod , Romero Daniel M , Zhao Xinyan , Yu Deahan , Gomez-Lopez Iris , Lu Jin Xiu , Iott Bradley E , Baylin Ana , Jansen Erica C , Clarke Philippa , Berrocal Veronica J , Goodspeed Robert , Veinot Tiffany C 
Published: September 2019

AbstractObjectiveInitiatives to reduce neighborhood-based health disparities require access to meaningful, timely, and local information regarding health behavior and its determinants. We examined the validity of Twitter as a source of information for neighborhood-level analysis of dietary choices and attitudes.Materials and MethodsWe analyzed the “healthiness” quotient and sentiment in food-related tweets at the census tract level, and associated them with neighborhood characteristics and health outcomes. We analyzed keywords driving the differences in food healthiness between the most and least-affluent tracts, and qualitatively analyzed contents of a random sample of tweets.ResultsSignificant, albeit weak, correlations existed between healthiness and sentiment in food-related tweets and tract-level measures of affluence, disadvantage, race, age, U.S. density, and mortality from conditions associated with obesity. Analyses of keywords driving the differences in food healthiness revealed foods high in saturated fat (eg, pizza, bacon, fries) were mentioned more frequently in less-affluent tracts. Food-related discussion referred to activities (eating, drinking, cooking), locations where food was consumed, and positive (affection, cravings, enjoyment) and negative attitudes (dislike, personal struggles, complaints).DiscussionTweet-based healthiness scores largely correlated with offline phenomena in the expected directions. Social media offer less resource-intensive data collection methods than traditional surveys do. Twitter may assist in informing local health programs that focus on drivers of food consumption and could inform interventions focused on attitudes and the food environment.ConclusionsTwitter provided weak but significant signals concerning food-related behavior and attitudes at the neighborhood level, suggesting its potential usefulness for informing local health disparity reduction efforts.
Emotion sharing in remote patient monitoring of patients with chronic kidney disease
Authors: Huang Robin , Liu Na , Nicdao Mary Ann , Mikaheal Mary , Baldacchino Tanya , Albeos Annabelle , Petoumenos Kathy , Sud Kamal , Kim Jinman 
Published: October 2019

Abstract

Objective
To investigate the relationship between emotion sharing and technically troubled dialysis (TTD) in a remote patient monitoring (RPM) setting.

Materials and Methods
A custom software system was developed for home hemodialysis patients to use in an RPM setting, with focus on emoticon sharing and sentiment analysis of patients’ text data. We analyzed the outcome of emoticon and sentiment against TTD. Logistic regression was used to assess the relationship between patients’ emotions (emoticon and sentiment) and TTD.

Results
Usage data were collected from January 1, 2015 to June 1, 2018 from 156 patients that actively used the app system, with a total of 31 159 dialysis sessions recorded. Overall, 122 patients (78%) made use of the emoticon feature while 146 patients (94%) wrote at least 1 or more session notes for sentiment analysis. In total, 4087 (13%) sessions were classified as TTD. In the multivariate model, when compared to sessions with self-reported very happy emoticons, those with sad emoticons showed significantly higher associations to TTD (aOR 4.97; 95% CI 4.13–5.99; P = &lt; .001). Similarly, negative sentiments also revealed significant associations to TTD (aOR 1.56; 95% CI 1.22–2; P = .003) when compared to positive sentiments.

Discussion
The distribution of emoticons varied greatly when compared to sentiment analysis outcomes due to the differences in the design features. The emoticon feature was generally easier to understand and quicker to input while the sentiment analysis required patients to manually input their personal thoughts.

Conclusion
Patients on home hemodialysis actively expressed their emotions during RPM. Negative emotions were found to have significant associations with TTD. The use of emoticons and sentimental analysis may be used as a predictive indicator for prolonged TTD.
The Greenconsumption Effect: How Using Green Products Improves Consumption Experience
Authors: Tezer Ali , Bodur H Onur 
Published: September 2019

Abstract
In many situations, consumers use green products without a deliberate choice to use or purchase the product. This research explores how using a green product (e.g., a pair of headphones made from recycled materials) influences the enjoyment of the accompanying consumption experience (e.g., listening to music), even if consumers have not deliberately chosen or purchased the product. Five experiments in actual consumption settings revealed that using a green (vs. conventional) product enhances the enjoyment of the accompanying consumption experience, referred to as the greenconsumption effect. Merely using a green product makes consumers perceive an increase in the extent to which they are valued as individuals by society, which leads to warm glow feelings, and consequently enhances the enjoyment of the accompanying consumption experience. When consumers experience low social worth, the positive effect of using green products on the accompanying consumption experience is amplified. The greenconsumption effect disappears when the negative environmental impact of the green product attribute is low. From a managerial standpoint, the current research identifies instances where brands can benefit from going green and encourages marketers, especially service providers, to promote green products that are instrumental in consumption experiences.
Grand Corruption and the International Criminal Court in the ‘Venezuela Situation’
Authors: Roht-Arriaza Naomi , Martínez Santiago 
Published: October 2019

Abstract
Venezuela’s ongoing crisis has resulted in the first-ever joint request from states parties to the International Criminal Court (ICC) to open a preliminary examination. The evidence presented until now of crimes against humanity focuses on attacks on political opposition and demonstrators. We contend that the situation in Venezuela is not fully comprehensible, and the referral falls short, without the use of the lens of grand corruption. We describe what we mean by ‘grand corruption’, how it has corroded Venezuela, and why grand corruption and the atrocities are connected. We explain how every step of the preliminary examination process is better understood if a corruption-infused analysis is brought to bear upon it. We then turn to some caveats and limiting considerations. Finally, we draw some implications for other, increasingly common, situations where grave violations of international criminal law take place because of, and are maintained by, systems of kleptocracy.
BDI logic applied to a dialogical interpretation of human–machine cooperative dialogues
Authors: Sierra Pablo 
Published: October 2019

Abstract
We first define a language for the dialogical logic and the models that the language generates. This language is thought to capture the structure of the dialogues captured by Lekta—a software framework oriented to the design and implementation of natural language processing-related applications—and its users. These dialogues are defined as cooperative dialogues in which the dialogical logic perspective of a dialogue seen as a competition is shifted into a perspective in which both agents cooperate towards a common goal. Later we define a BDI temporal logic based on a modal framework that we will use to study the beliefs, desires and intentions of both agents based on the model generated by the dialogical logic.
Effects of Aqueous Extracts from Amazon Plants on Plutella xylostella (Lepidoptera: Plutellidae) and Brevicoryne brassicae (Homoptera: Aphididae) in Laboratory, Semifield, and field trials
Authors: Cerda Hugo , Carpio Carlos , Ledezma-Carrizalez A Carolina , Sánchez Jessica , Ramos Luis , Muñoz-Shugulí Cristina , Andino Marco , Chiurato Matteo 
Published: September 2019

Abstract
We evaluated the insecticide activities of aqueous extracts of five species of plants from the Ecuadorian Amazon (Deguelia utilis (ACSm.) AMGAZEVEDO (Leguminosae: Papilionoideae), Xanthosoma purpuratum K. Krause (Alismatales: Araceae), Clibadium sp. (Asteracea: Asterales), Witheringia solanacea L'Hér (Solanales: Solanaceae), and Dieffenbachia costata H. Karst. ex Schott (Alismatales: Araceae)) plus Cymbopogon citratus Stapf. (Poales: Poaceae) under laboratory, open-field conditions in Plutella xylostella L. (diamondback moth), and semifield conditions in Brevicoryne brassicae L. Tap water was used as a negative control, and synthetic insecticides were used as positive controls. In a laboratory bioassay, aqueous extracts of D. utilis resulted in P. xylostella larval mortality. In contrast to chlorpyrifos, all botanicals were oviposition deterrents. All extracts except Clibadium sp. decreased leaf consumption by P. xylostella larvae. In semifield experiments, D. utilis, Clibadium sp., D. costata, and X. purpuratum initially controlled the population of B. brassicae, but 7 d after application, all botanicals except the D. utilis lost their ability to control the pest. In field experiments on broccoli crops in both dry and rainy seasons, the extracts did not control the abundance of P. xylostella, where as a mixture of two insecticides (chlorpyrifos + lambda cyhalothrin) did. These results show some incongruences from laboratory to semifield and field conditions, indicating that more studies, including the identification of the chemicals responsible for the biological activity, its stability, and the effects of chemotypes on insecticidal activity, are needed to understand the potential of these plant species as botanical insecticides.
Clinical impact of renal impairment on the safety and efficacy of S-1 plus oxaliplatin in patients with advanced gastric cancer: a single institutional study
Authors: Demachi Ken , Bando Hideaki , Nomura Hisanaga , Shitara Kohei , Yoshino Takayuki , Yamaguchi Masakazu , Kawasaki Toshikatsu 
Published: October 2019

Abstract

Backgrounds
S-1 plus oxaliplatin appears effective in chemo-naïve patients with advanced gastric cancer. However, comprehensive safety and efficacy data for S-1 plus oxaliplatin is limited for patients with impaired renal function.

Methods
We retrospectively extracted data from advanced gastric cancer patients with normal renal function (normal group, CLcr ≥ 60 ml/min), who were treated with standard doses of S-1 (80 mg/m2) plus oxaliplatin (100 mg/m2), and patients with impaired renal function (impaired group, CLcr < 60 ml/min) who were treated with standard or reduced doses of S-1 (60 mg/m2 or 40 mg/m2) plus standard doses of oxaliplatin. Treatment efficacy and safety between the groups were compared.

Results
Data from 100 normal patients and 42 patients with impaired renal function were extracted. Baseline characteristics differed significantly between the two groups, including age (median, 64 vs 72 years, P < 0.0001) and body surface area (median, 1.68 vs 1.51 m2, P < 0.0001). In the impaired group, 66.6% (28/42) started with a reduced dose. Within the impaired group, more patients had a reduced initial S-1 dose when CLcr <50 ml/min (77.3%). The median progression-free and overall survival between the normal and impaired groups was 6.1 vs 5.7 months (P = 0.698) and 16.1 vs 18.5 months (P = 0.638), respectively.

Conclusions
S-1 plus oxaliplatin in advanced gastric cancer patients with impaired renal function appears safe and has demonstrated efficacy given appropriate dose modification.