bluuebunny/crossref_metadata_2025_split huggingface dataset:
Space, time, condition: grammaticalisation of a demonstrative in Makhuwa
Authors: van der Wal Jenneke 
Published: September 2019

L’article décrit les divers contextes dans lesquels le démonstratif éloigné de classe 16 ‘vale’ est employé en makhuwa. La diversité synchronique de sa distribution suggère que le pronom a suivi un développement diachronique du type suivant : à partir d’un démonstratif locatif, il a glissé du domaine spatial au domaine temporel comme indicateur d’une séquence temporelle pour ensuite devenir un marqueur de l’hypothétique dans certaines propositions conditionnelles. Un résultat supplémentaire de ce processus de grammaticalisation pourrait être l’emploi de
vale dans des contextes qui paraissent marquer la supposition.
Les inclusions fluides des enclaves catazonales de Bournac (Massif central)
Authors: Bilal Ahmad , Touret Jacques 
Published: September 2019

The catazonal xenoliths occurring in the Bournac volcano (French Massif central) contain many « carbonic » fluid inclusions (CO₂, eventually hydrocarbons), and, more rarely some aqueous ones (only in the granitic xenoliths). PT estimates from fluid inclusions (CO₂ isochores, density between 1.075 and 0.72 g/cm³) agree with corresponding estimates derived independantly from the solid phases.
Quelques aspects des inclusions solides révélés par le microscope électronique à balayage sur l'exemple d'un quartz pegmatitique
Authors: Saintives Jean-Paul 
Published: September 2019

Le microscope électronique à balayage permet d'étudier la morphologie d'inclusions solides dont les dimensions sont fréquemment de l'ordre de 0,1 µm ainsi que leurs relations avec les lacunes de croissance et les cavités épigénétiques du minéral hôte. Ces observations apportent des informations sur la genèse des minéraux inclus.
Thermoluminescence des zircons du district aurifère de Salsigne (Aude, France). Implications génétiques
Authors: Laville-Timsit Liliane 
Published: September 2019

Une étude a été faite dernièrement sur les minéraux lourds du Cambrien inférieur du versant sud de la Montagne Noire. L'observation de la taille et de la forme des zircons a permis de les séparer en deux lots très différents. L'examen « grain par grain » de leur TL confirme cette distinction. La première famille, hétérogène, a une extension régionale : elle est d'origine détritique. La deuxième famille, homogène, est limitée au secteur minier : elle pourrait être néoformée.
Contribution à l'étude de la formation des gîtes silicatés de nickel
Authors: Perruchot Alain 
Published: September 2019

An experimental study of weathering of nickeliferous olivine and serpentine, using the « soxhlet » apparatus, shows that the two minerals behave in very different ways. While the serpentine undergoes a quasicongruent dissolution, the forsterite decays with formation of amorphous Si-enriched silico-magnesian products. Nickel shows a tendency to concentrate in such residual products. The factor of concentration is low in the case of serpentine. In the case of forsterite, the nickel percent in the amorphous products, resulting immediately from weathering, can exceed by twenty times the initial amount in forsterite. We show that these amorphous silicates behave like ions-exchangers in presence of nickel and magnesium. The high nickel amount of these products is explained by the high value, about 400, of the distribution coefficient D(Ni,Mg) = (Ni/Mg)[gel]/(Ni/Mg)[solution] ((Ni/Mg)[gel] and (Ni/Mg)[solution] are atomic ratios). These observations suggest that residual silicated ores could have undergone an amorphous stage during which nickel was concentrated by ion-exchange.
Étude du système Al2O3-SiO2-Na2O-H2O
Authors: Pertsowsky Raymond 
Published: September 2019

Ce système a été étudié en milieu hydrothermal entre 200 et 500° C, pour des domaines de concentrations variant de 1 à 6, pour SiO₂/Al₂O₃, et de 1 à 5 pour Na₂O/Al₂O₃. On constate que la pression toujours inférieure à 1 kbar, ne joue aucun rôle important, et on met en évidence les domaines de stabilité de nombreux minéraux dont l'analcite, la cancrinite et l'albite.
La réversibilité de ces équilibres et la limite des domaines de stabilité ont été vérifiées plus particulièrement.
Análise da Percepção Motivacional dos Discentes: Estudo Comparativo entre Períodos Letivos e o Uso da Gamificação
Authors: Murtinho Amanda de Britto Murtinho de Britto , Giordano Carlos Vital , Florença Diego Felipe 
Published: September 2019

Diante da problemática do desencontro geracional que tende a provocar o desestímulo e a falta de engajamento dos estudantes atualmente, discutese a possibilidade da utilização dos jogos (games) e/ou da gamificação como instrumentos motivadores no ensino-aprendizagem, explorando, além do referencial teórico, os dados de estudo de campo que avaliou a percepção motivacional de um grupo de estudantes monitorados em dois diferentes momentos – o primeiro com e o segundo sem a utilização dos jogos, chegando-se à conclusão de que os games favorecem o desejável entrosamento do discente em sala de aula, não sendo, contudo, capazes de promover metodologias ativas e inovadoras por si só – motivo pelo qual os gestores devem estar cônscios dos objetivos que pretendem alcançar a partir de qualquer que seja o instrumental adotado.
Leitura e Educação: Determinações Educacionais e a Categoria Particularidade em o Filho Maldito de Balzac
Authors: Franco Sandra Aparecida Pires , Girotto Cyntia G. G. Simões G. G. Simões , Fujita Elza Tie Tie , Trassi Angélica Polvani 
Published: September 2019

O objetivo deste estudo é o de analisar a particularidade da criação artística na obra O Filho Maldito de Balzac. Para tanto, é imprescindível a compreensão das determinações sociais, educacionais e as contradições presentes no comportamento dos personagens. Trata-se de uma pesquisa bibliográfica e documental, com abordagem crítico-dialética. A leitura e análise da obra permitiram verificar que esta retrata uma França em período de transição, da Idade Média para a sociedade Capitalista, com o surgimento da nova classe social: a burguesia e os comportamentos humanos deste período. A leitura dessa obra permitiu concluir, portanto, que a leitura literária possibilita ao leitor a percepção de diversos contextos históricos, sociais e culturais, bem como, o comportamento humano frente as realidades sociais vigentes, possibilitando a formação de leitores mais conscientes.
HUBUNGAN PENGETAHUAN DAN MINAT PEKERJA SEKS KOMERSIAL DALAM PENGGUNAAN KONDOM WANITA DI LOKALISASI BOLODEWO KECAMATAN WATES KABUPATEN KEDIRI.
Authors: Endarwati Susiani , Dyan Putri Dwi Friska 
Published: September 2019

Kondom wanita merupakan alat yang digunakan selama hubungan seksual. Banyak wanita terjerumus ke dalam bisnis prostitusi, tetapi semakin banyaknya bisnis tersebut tidak dibarengi dengan kesadaran pelaku untuk menjaga dirinya dari ancaman penyakit menular seksual. Tujuan dalam penelitian ini adalah untuk mengetahui hubungan pengetahuan dan minat pekerja seks komersial dalam penggunaan kondom wanita di Lokalisasi Bolodewo Kec. Wates Kab.Kediri.
Desain yang digunakan adalah studi korelasi dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah semua pekerja seks komersial sebanyak 60 orang. Pengambilan sampel menggunakan teknik total sampling. Variabel dalam penelitian ini yaitu variabel independen adalah pengetahuan pekerja seks komersial tentang kondom wanita dan variabel dependen adalah minat pekerja seks komersial dalam penggunaan kondom wanita. Pengumpulan data menggunakan kuesioner. Pengolahan data meliputi Editing, Coding, Scoring, Tabulating, dianalisa menggunakan uji Spearman Rank.
Hasil dari penelitian diperoleh bahwa pengetahuan pekerja seks komersial tentang kondom waanita dalam katekori cukup (41,7%), dan minat pekerja seks komersial dalam penggunaan kondom wanita dalam kategori tinggi (61,7%). Dari data tersebut dilakukan uji statistik dengan hasil sig (p) = 0,000 dan ɑ=0,05 jadi H0 ditolak dan H1 diterima.
Berdasarkan hasil penelitian dapat disimpulkan bahwa ada hubungan pengetahuan dan minat pekerja seks komersial dalam penggunaan kondom wanita. Diharapkan pekerja seks komersial memakai kondom wanita setiap melakukan hubungan seksual, untuk mencegah kehamilan dan penyakit menular seksual. Peran tenaga kesehatan diperlukan untuk memotivasi pekerja seks komersial dalam penggunaan kondom wanita.

Kata Kunci : Pengetahuan, minat, pekerja seks komersial, kondom wanita
Hubungan Pemberian ASI Eksklusif dengan Perkembangan Ketrampilan Makan Bayi Usia 6-12 Bulan
Authors: Nurcahyani Budi , Mexitalia Maria , Susanto J , Sakundarno M 
Published: September 2019

Latar belakang : Walaupun WHO tahun 2001 telah mengeluarkan deklarasi tentang ASI eksklusif sampai bayi usia 6 bulan, tetapi sebagian besar bayi tidak mendapatkan ASI eksklusif. Ketrampilan makan bayi yang diawali dengan belajar menyusu ibu, secara bertahap diikuti dengan belajar mengkonsumsi berbagai jenis makanan pendamping ASI dan selanjutnya beraneka ragam makan lain yang biasa dikonsumsi oleh anak yang lebih besar atau orang dewasa. Perkembangan motorik kasar, motorik halus, motorik oral, merupakan dasar penilaian ketrampilan makan dan pemberian makanan tambahan pada anak. Penelitian ini bertujuan untuk mengetahui hubungan pemberian ASI eksklusif dengan perkembangan ketrampilan makan pada bayi. Metode : Desain penelitian ini adalah longitudinal prospektif dengan subyek bayi usia 6 -2 bulan di Kelurahan Sendangguwo, Kecamatan Tembalang-Semarang. Subyek penelitian terdiri dari 69 bayi. Diikuti lama pemberian ASI eksklusif, cara pemberian makan, jenis makanan yang diberikan. Kemudian dinilai perkembangan motorik oral, motorik kasar, motorik halus dan ketrampilan makan setiap bulan sampai anak usia 12 bulan.Â Hasil : Dari total sampel 69 bayi, terdapat 23 bayi yang mendapatkan ASI eksklusif selama 4 bulan dan 46 bayi yang tidak mendapatkan ASI eksklusif. Rerata pemberian ASI eksklusif selama 2,31 bulan. Pemberian ASI eksklusif paling lama pada ibu dengan pendidikan sedang. Perkembangan motorik kasar, motorik halus, motorik oral pada penelitian ini memiliki kisaran umur yang luas. Tidak terdapat perbedaan bermakna antara kelompok bayi yang mendapat ASI eksklusif 4 bulan dan bayi yang tidak mendapat ASI eksklusif dengan perkembangan ketrampilan makan pada bayi usia 6 bulan, 9 bulan dan 12 bulan. Pada usia 12 bulan didapatkan semua bayi mempunyai ketrampilan makan sesuai umur. Simpulan : Tidak ada perbedaan yang bermakna pada perkembangan ketrampilan makan antara kelompok bayi yang mendaptkan ASI eksklusif 4 bulan dan kelompok bayi yang tidak mendapat ASI eksklusif.
Comparison of clinical and pathological features of lymph node tuberculosis and histiocytic necrotizing lymphadenitis
Authors: Yang Jin-sun , Du Zhi-xiang 
Published: September 2019

Introduction: The aim of this study was to investigate the basis for a differential diagnosis of lymph node tuberculosis and histiocytic necrotizing lymphadenitis.
Methodology: This study selected 85 cases of lymph node tuberculosis (Group A patients) and 26 cases of histiocytic necrotizing lymphadenitis (Group B patients). The clinical and pathology features on both groups were analysed.
Results: The Group A patients were older than the Group B patients (t = 5.233, P < 0.01); The Group B patients had less tuberculosis exposure history (x2 = 4.279, P < 0.01), and a higher frequency of tenderness (χ2 = 8.109, P < 0.01) and fever (x2 = 31.923, P < 0.01). The Group A patient group had a higher WBC level (t = 2.980, P < 0.01) and lower serum ALB (t = 5.508, P < 0.01); As seen through ultrasound imaging, Group B patients had more clear boundaries (70.59%), higher low-echo rates (82.36%) and low calcification rates (0%), Group A patients for whom these rates was 25.76%, 40.91% and 25.76% respectively. In terms of pathology data, the main manifestations of Group A patients were granulomatous inflammation with caseous necrosis, multinuclear giant cell reaction, and in some cases, acid-fast bacilli smears (+). In Group B patients, there were instances of coagulative necrosis surrounded by foam-like tissue cells without neutrophil infiltration.
Conclusion: We found that the epidemiological history, clinical symptoms, laboratory examinations, ultrasound imaging and changes in pathology are very important for the identification of lymph node tuberculosis and histiocytic necrotizing lymphadenitis.
Functional landscape of Sila Grande (Calabria, Italy): Vegetation dynamism and synphytosociology
Authors: Uzunov Dimitar , Gangale Carmen 
Published: September 2019

The aim of this presentation is to present practical problems related to the land management and biodiversity conservation, using methods of landscape analysis through approaches of synphytosociology. The study area was Sila Grande (Calabria, S Italy), for which an exhaustive bibliographic analysis was carried out and cartographic materials were collected. Spatial data and different themes were organized in a Geographic Information System (GIS), proceeding with a first segmentation (environmental patches identification) based on geomorphologic, geological land use, bioclimatic, etc. In addition, an analysis of mountainous plant communities was carried out, based on 1047 phytosociological relevés (554 original) in order to investigate paleo-geographic, ecological and anthropic factors that influence floral and vegetation diversity.
Data from literature and field studies (1998–2013) have been critically analyzed in order to clarify the syntaxonomic position of the main vegetation types. Twenty-six new syntaxa (associations and subassociations) are proposed and an updated sintaxonomic scheme is presented.
Querco-Fagetea and Molinio-Arrhenetheretea are the most represented classes in the area due to the bioclimatic factors. Wet communities (Isoeto-Nanojuncetea, Nardetea strictae, ScheuchzerioCaricetea fuscae, Montio-Cardaminetea and Littorelletea uniflorae) have a significant biogeographical importance due to a rich group of boreal species. This “Nordic imprint” of the flora, vegetation and landscape is of special interest and its peculiarities are analyzed from ecological and biogeographycal point of view. Mediterranean and sub-Mediterranean elements prevail in the dry grasslands and shrublands.
Some problems about the dynamics of vegetation are discussed such as the role of black pine communities and their relations with beech forests, trying also to provide clues for conservation strategies and management.
Relationship between land use and water quality in a watershed impacted by iron ore tailings and domestic sewage
Authors: Nascimento Laura Pereira do , Reis Deyse Almeida , Roeser Hubert Mathias Peter , Santiago Aníbal Da Fonseca 
Published: September 2019

Changes in land use and land cover in watersheds, together with population increases and urbanization of these areas, have caused negative impacts on surface water quality. Based on land-use types, we conducted a comprehensive water quality study of the Rio do Peixe watershed, a tributary of the Rio Doce River, located in the Iron Quadrangle, with different land uses/land covers. For this study, the relationship between water quality variables and land use types were examined according to the water quality index and principal components analysis. The water samples were collected from twelve stations located along the basin in two different seasons. The results of metals/semimetals concentrations reflected regional lithology, and in the case of iron, it was anthropic activities. Also, the computed water quality index values were between 26.8 and 74.9. The water quality was poor in four stations of the river basin in both seasons. Furthermore, the variables that influence water quality the most were E. coli, DBO, turbidity, nitrate, and total phosphorus. The multivariate statistics gave five principal components that together accounted for 58.3%, whereas analysis of score plots identified the formation of two groups with more perceptible anthropic influence. Finally, environmental impacts of the river basin, such as deforestation, erosion, domestic sewage, and iron ore tailings, were the main factors that interfered with water quality.
Potent HIV‐1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein‐Ligand X‐ray Structural Studies
Authors: Ghosh Arun K. , Xia Zilei , Kovela Satish , Robinson William L. , Johnson Megan E. , Kneller Daniel W. , Wang Yuan‐Fang , Aoki Manabu , Takamatsu Yuki , Weber Irene T. , Mitsuya Hiroaki 
Published: September 2019

AbstractWe report the synthesis and biological evaluation of phenylcarboxylic acid and phenylboronic acid containing HIV‐1 protease inhibitors and their functional effect on enzyme inhibition and antiviral activity in MT‐2 cell lines. Inhibitors bearing bis‐THF ligand as P2 ligand and phenylcarboxylic acids and carboxamide as the P2′ ligands, showed very potent HIV‐1 protease inhibitory activity. However, carboxylic acid containing inhibitors showed very poor antiviral activity relative to carboxamide‐derived inhibitors which showed good antiviral IC50 value. Boronic acid derived inhibitor with bis‐THF as the P2 ligand showed very potent enzyme inhibitory activity, but it showed lower antiviral activity than darunavir in the same assay. Boronic acid containing inhibitor with a P2‐Crn‐THF ligand also showed potent enzyme Ki but significantly decreased antiviral activity. We have evaluated antiviral activity against a panel of highly drug‐resistant HIV‐1 variants. One of the inhibitors maintained good antiviral activity against HIVDRVRP20 and HIVDRVRP30 viruses. We have determined high resolution X‐ray structures of two synthetic inhibitors bound to HIV‐1 protease and obtained molecular insight into the ligand‐binding site interactions.
Theory of electrophoretic focusing on an inverse electromigration dispersion profile
Authors: Gebauer Petr 
Published: September 2019

AbstractElectrophoretic focusing on an inverse electromigration dispersion (EMD) profile is based on a principle different from those of other electrophoretic separation methods. It has already proved its applicability in analytical practice by offering competitive separation performance and sensitivity and specific selectivity. It can be classified as an intermediate between field‐driven and equilibrium gradient methods and is therefore interesting from the viewpoint of theory of separation methods. This work presents a comprehensive theoretical description of electrophoretic focusing on an inverse EMD profile comprising properties of the electrolyte system, formed gradients, and focused analyte zones. The separation properties are described in terms of resolution and peak capacity and their dependence on system and analyte properties is discussed from the viewpoint of how the counteracting phenomena of electromigration and dispersion are affected by electric current, voltage, and hydrodynamic and electroosmotic flow. The overall performance of the present method is shown to be comparable with other electrophoretic separation methods like zone electrophoresis or isoelectric focusing.
Investigation of Sustained BMP Delivery in the Prevention of Medication‐Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model
Authors: Brierly Gary I. , Ren Jiongyu , Baldwin Jeremy , Saifzadeh Siamak , Theodoropoulos Christina , Tsurkan Mikhail V. , Lynham Anthony , Hsu Edward , Nikolarakos Dimitrios , Werner Carsten , Woodruff Maria A. , Hutmacher Dietmar W. , Bray Laura J. 
Published: September 2019

AbstractMedication‐related osteonecrosis of the jaw (MRONJ) poses an ongoing challenge for clinicians and researchers. Currently, there is a lack of preventative measures available for at‐risk patients undergoing tooth extractions, especially those with prior bisphosphonate treatment due to osteoporosis or bone metastasis diagnoses. Here, these issues are addressed using a preventative tissue engineering strategy against MRONJ development. This study evaluates the efficacy of a poly(ethylene glycol)‐heparin hydrogel as a tool for the delivery of arginylglycylaspartic acid (RGD) and recombinant human bone morphogenic protein‐2 (rhBMP‐2). Three groups of skeletally mature rats each receive two doses of intravenous zoledronic acid prior to surgery and undergo extraction of the right first mandibular molar with gingival closure. Experimental groups either have the sockets left empty, filled with hydrogel minus rhBMP‐2, or filled with hydrogel plus rhBMP‐2. Eight weeks postoperatively specimens are analyzed using radiological, histological, and scanning electron microscopy (SEM) techniques. µCT analysis shows increased bone formation with hydrogel/rhBMP‐2 delivery compared to the empty socket. Hydrogel‐treated groups display increased presence of osteocytes and increased osteoclastic action compared to the empty sockets. These results represent the first step toward improved delivery of rhBMP‐2 and a potential MRONJ preventative for patients undergoing bisphosphonate treatment.
Use of Fish Oil Intravenous Lipid Emulsions as Monotherapy in the Pediatric Intestinal Failure Patient: Beyond the Package Insert
Authors: Gura Kathleen M. , Calkins Kara L. , Puder Mark 
Published: September 2019

AbstractIn July 2018, an intravenous lipid emulsion (ILE) composed of 100% fish oil (Omegaven, Fresenius Kabi, Bad Homburg, Germany) received Food and Drug Administration (FDA) approval as a source of fatty acids and calories for infants and children with parenteral nutrition–associated cholestasis. This soy‐free fat source is rich in ω‐3 fatty acids and α‐tocopherol and contains few phytosterols. In comparison to conventional soybean oil ILE, this emulsion appears to be less hepatotoxic. The purpose of this paper is to guide the practitioner on the use of this alternative fat source in clinical practice and augment the material contained in the current package insert. This paper addresses various topics including the identification of which patients would benefit from fish oil ILE, dosing, administration, monitoring, potential adverse effects, and management strategies for fish oil ILE.
Assessment of the oral health‐related quality of life and the health‐related quality of life of patients with stomatological diseases
Authors: Kuryu Mai , Niimi Kanae , Gotoh Hideki , Shimizu Takeshi , Kobayashi Tadaharu 
Published: September 2019

AbstractObjectiveThe aim of the study was to clarify the factors affecting the oral health‐related quality of life (OHRQOL) and the general health‐related quality of life (HRQOL) of patients with stomatological diseases and to assess the correlation between the HRQOL and the OHRQOL scales in these patients.Study designThe study population included 2061 patients with stomatological diseases and was divided into five groups: tooth disease, inflammatory disease, oral mucosal disease, temporomandibular joint disorder, and cystic disease. The patients filled out the Short Form 8 Health Survey (SF‐8) and the General Oral Health Assessment Index (GOHAI). A Kruskal‐Wallis one‐way analysis and pairwise comparison were used to compare the mean scores of GOHAI and SF‐8 according to the disease classification. Welch's t test was used to compare the mean GOHAI and SF‐8 scores using the Japanese national normative data. P values of <.05 were considered to indicate statistical significance.ResultsStomatological diseases affect both OHRQOL and HRQOL, and the physical items of the HRQOL were significantly correlated with the OHRQOL. When the mean GOHAI and SF‐8 scores were compared according to disease classification, statistically significant differences were seen in most all items. Patients with oral mucosal disease, TMJ disorder, and inflammatory disease had lower scores in most of the scales than patients with other diseases.ConclusionsThe assessment of the relationship between OHRQOL and HRQOL of patients with stomatological diseases seems to be useful in understanding problems related to patient well‐being.