bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost utility analysis of end stage renal disease treatment in Ministry of Health dialysis centres, Malaysia: hemodialysis versus continuous ambulatory peritoneal dialysis
Authors: Surendra Naren Kumar , Abdul Manaf Mohd Rizal , Hooi Lai Seong , Bavanandan Sunita , Mohamad Nor Fariz Safhan , Firdaus Khan Shahnaz Shah , Meng Ong Loke , Abdul Gafor Abdul Halim 
Published: June 2019

AbstractOBJECTIVESIn Malaysia, there is exponential growth of patients on dialysis. Dialysis treatment consumes a considerable portion of healthcare expenditure. Comparative assessment of their cost effectiveness can assist in providing a rational basis for preference of dialysis modalities.METHODSA cost utility study of hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) was conducted from a Ministry of Health (MOH) perspective. A Markov model was also developed to investigate the cost effectiveness of increasing uptake of CAPD to 55% and 60 % versus current practice of 40% CAPD in a five-year temporal horizon. A scenario with 30% CAPD was also measured. The costs and utilities were sourced from published data which were collected as part of this study. The transitional probabilities and survival estimates were obtained from the Malaysia Dialysis and Transplant Registry (MDTR). The outcome measures were cost per life year (LY), cost per quality adjusted LY (QALY) and incremental cost effectiveness ratio (ICER) for the Markov model. Sensitivity analyses were performed.RESULTSLYs saved for HD was 4.15 years and 3.70 years for CAPD. QALYs saved for HD was 3.544 years and 3.348 for CAPD. Cost per LY saved was RM39,791 for HD and RM37,576 for CAPD. The cost per QALY gained was RM46,595 for HD and RM41,527 for CAPD. The Markov model showed commencement of CAPD in 50% of ESRD patients as initial dialysis modality was very cost-effective versus current practice of 40% within MOH. Reduction in CAPD use was associated with higher costs and a small devaluation in QALYs.CONCLUSIONSThese findings suggest provision of both modalities is fiscally feasible; increasing CAPD as initial dialysis modality would be more cost-effective.
The evolution of contact prediction: Evidence that contact selection in statistical contact prediction is changing
Authors: Chonofsky Mark , de Oliveira Saulo H. P. , Krawczyk Konrad , Deane Charlotte M. 
Published: June 2019

AbstractOver the last few years, the field of protein structure prediction has been transformed by increasingly-accurate contact prediction software. These methods are based on the detection of coevolutionary relationships between residues from multiple sequence alignments. However, despite speculation, there is little evidence of a link between contact prediction and the physico-chemical interactions which drive amino-acid coevolution. Furthermore, existing protocols predict only a fraction of all protein contacts and it is not clear why some contacts are favoured over others.Using a dataset of 863 protein domains, we assessed the physico-chemical interactions of contacts predicted by CCMpred, MetaPSICOV, and DNCON2, as examples of direct coupling analysis, meta-prediction, and deep learning, respectively. To further investigate what sets these predicted contacts apart, we considered correctly-predicted contacts and compared their properties against the protein contacts that were not predicted.We found that predicted contacts tend to form more bonds than non-predicted contacts, which suggests these contacts may be more important. Comparing the contacts predicted by each method, we found that metaPSICOV and DNCON2 favour accuracy whereas CCMPred detects contacts with more bonds. This suggests that the push for higher accuracy may lead to a loss of physico-chemically important contacts.These results underscore the connection between protein physico-chemistry and the coevolutionary couplings that can be derived from multiple sequence alignments. This relationship is likely to be relevant to protein structure prediction and functional analysis of protein structure and may be key to understanding their utility for different problems in structural biology.Author summaryAccurate contact prediction has allowed scientists to predict protein structures with unprecedented levels of accuracy. The success of contact prediction methods, which are based on inferring correlations between amino acids in protein multiple sequence alignments, has prompted a great deal of work to improve the quality of contact prediction, leading to the development of several different methods for detecting amino acids in proximity.In this paper, we investigate the properties of these contact prediction methods. We find that contacts which are predicted differ from the other contacts in the protein, in particular they have more physico-chemical bonds, and the predicted contacts are more strongly conserved than other contacts across protein families. We also compared the properties of different contact prediction methods and found that the characteristics of the predicted sets depend on the prediction method used.Our results point to a link between physico-chemical bonding interactions and the evolutionary history of proteins, a connection which is reflected in their amino acid sequences.
Integration of genomic variation and phenotypic data using HmtPhenome
Authors: Preste R. , Attimonelli M. 
Published: June 2019

AbstractA full understanding of relationships between variants, genes, phenotypes and diseases is often overlooked when investigating mitochondrial functionality in both healthy and pathological situations. Gaining a comprehensive overview of this network can indeed offer interesting insights, and guide researchers and clinicians towards a full-spectrum knowledge of the mitochondrial system.Given the current lack of tools addressing this need, we have developed HmtPhenome (https://www.hmtphenome.uniba.it), a new web resource that aims at providing a visual network of connections among variants, genes, phenotypes and diseases having any level of involvement in the mitochondrial functionality. Data are collected from several third party resources and aggregated on the fly, allowing users to clearly identify interesting relations between the involved entities. Tabular data with additional hyperlinks are also included in the output returned by HmtPhenome, so that users can extend their analysis with further information from external resources.
An efficient coupled pressure–velocity solver for three-dimensional injection molding simulation using Schur complement preconditioned FGMRES
Authors: Liu Xiang , Guo Fei , Zhang Yun , Liang Junjie , Li Dequn , Zhou Huamin 
Published: June 2019

Purpose
The purpose of this paper is to develop a coupled approach to solve the pressure–velocity-coupled problem efficiently in the three-dimensional injection molding simulation.

Design/methodology/approach
A fully coupled pressure–velocity algorithm is developed to solve the coupled problem, by treating the pressure gradient term implicitly. And, the Schur complement preconditioned FGMRES is applied to decompose the resulting coupled pressure–velocity equation into pressure and velocity subsystems. Then, BoomerAMG is adopted to solve the pressure subsystem, and block Jacobi preconditioned FGMRES is applied to the velocity subsystem.

Findings
According to the several experiments, the fully coupled pressure–velocity algorithm was demonstrated to have faster convergence than the traditional SIMPLE algorithm, and the calculating time was reduced by up to 70 per cent. And, the Schur complement preconditioned FGMRES worked more efficiently than block Gauss–Seidel preconditioned FGMRES, block-selective AMG and AMG with block ILU(0) smoother and could take at least 47.4 per cent less time. The proposed solver had good scalability for different-size problems, including various cases with different numbers of elements. It also kept good speedup and efficiency in parallel performance.

Originality/value
A coupled solver has been proposed to effectively solve the coupled problem in the three-dimensional injection molding simulation, which is more robust and efficient than existing methods.
Cruise brand experience: functional and wellness value creation in tourism business
Authors: Ahn Jiseon , Back Ki-Joon 
Published: June 2019

Purpose
Experience and value creation have become integral themes for tourism service providers. This study aims to understand the role of different types of experiences in formulating customers’ perceived value. Studies on this area are scarce, especially in the cruise industry.

Design/methodology/approach
A research model that includes two value variables, namely, functional and wellness values, and four cruise brand experience variables, namely, sensory, affective, behavioral and intellectual factors, was tested through partial least-squares (PLS) structural equation modeling approach. A total of 389 usable cruise customer responses were obtained and analyzed using SmartPLS software.

Findings
Results revealed the relative effects of sensory, affective, behavioral and intellectual factors on perceived functional and wellness values. The positive impact of perceived value on customer satisfaction and behavioral intention and the moderating role of service expertise in the relationship between cruise experience and perceived value were examined.

Research limitations/implications
Future research can examine how types of leisure facilities (e.g. casinos, restaurants, bars and shows), cultural differences (e.g. Eastern and Western) and customers’ travel characteristics (e.g. visiting purpose and companions) may influence the relationships between cruise brand experience and perceived value.

Practical implications
From a practical point, the relationships among multidimensional cruise brand experience, functional and wellness values, customer satisfaction, revisit intention and service expertise provide a clue on how cruise brands can enhance customers’ perceived value to retain current customers.

Originality/value
This study contributes to literature by providing a theoretical framework and empirical evidence for predicting and explaining cruise customers’ behavior. From a managerial perspective, this study identified critical factors that are essential to value creation and discussed the implications of predictive factors on developing marketing strategies that enhance customers’ positive attitude and behavior toward the cruise brand.
Improving vocational recovery among people with psychosis: a two-pronged approach
Authors: Turner Niall , Nesbitt Tara , Fanning Felicity , Clarke Mary 
Published: June 2019

PurposeThis paper aims to investigate the feasibility of conducting research on a two-pronged vocational intervention for people with first episode psychosis. The paper also aims to empirically examine the impact of a two-pronged vocational intervention for people with first episode psychosis by determining what effect, if any, introducing a two-pronged vocational intervention to an early intervention for psychosis service (EIPS) has on vocational outcomes using a prospective follow-up design. The approach consisted of supported employment (individual placement and support, IPS) for participants without a productive role and a job retention programme for those employed or studying.Design/methodology/approachBetween 2010 and 2013, a supported employment specialist joined an EIPS where occupational therapy was available to all attenders. The appropriate intervention was determined by the occupational therapist on the team. Participants were interviewed at baseline and one follow-up. Ethical approval was attained. The Individual Placement and Support Fidelity Scale was used to ensure the quality of IPS implementation.FindingsIn total, 39 (20 men, 19 women) consented; 21 (54 per cent) of these participants were unoccupied; 18 (46 per cent) had a productive role; 87 per cent (n= 34) were followed up. The mean length of follow-up was 18 months. At follow-up, 50 per cent (n= 10) of unoccupied participants had attained a productive role, and 17 of the 18 participants had retained their productive role. Overall, participants were found to have spent an average of 62 per cent of the follow-up period in a productive role.Research limitations/implicationsRates of vocational recovery among people affected by psychosis may be enhanced by a two-pronged approach that allows for the persons individual work circumstances to be taken into account.Originality/valueThis study highlights the impact of a two-progroned vocational intervention for people with first episode psychosis in Ireland. It is the first study of its kind to be published in the Republic of Ireland and the first world-wide to include a job retention element in its design.
Bank productivity in Africa
Authors: Nartey Sarah Beatson , Osei Kofi A. , Sarpong-Kumankoma Emmanuel 
Published: June 2019

Purpose
The purpose of this paper is to provide a total factor productivity index for the African banking industry. It also investigates the impact of some internal and external determinants affecting bank productivity.

Design/methodology/approach
The biennial Malmquist productivity index and various regression models (ordinary least squares, Tobit and truncated bootstrapped regression) are employed in analyzing data from 120 banks in 24 African countries from 2007 to 2012.

Findings
The results indicate a general decline in productivity of banks in Africa, largely due to inadequate technological progress. State banks are found to be more productive than foreign and private banks. The regression analyses showed that non-executive directors, leverage, management quality, credit risk, competition and exchange rate have significant impact on bank productivity, but ownership and CEO-duality do not.

Practical implications
The results have implications for management of banks, governments and regulators. It shows the need for policy and investments that improve state-of-the art technology. The findings also seem to suggest poor management practices in input usage, especially in operational management, as well as costs emanating from non-interest sources. Bank managers need to address these deficiencies to improve productivity in African banking markets.

Originality/value
A major contribution of this paper is the productivity index provided for the African banking industry. This study is also the first to apply the biennial Malmquist to analyze productivity in the African banking industry.
Logistics performance collaboration strategy and information sharing with logistics capability as mediator variable (study in Gafeksi East Java Indonesia)
Authors: Kirono Indro , Armanu Armanu , Hadiwidjojo Djumilah , Solimun Solimun 
Published: June 2019

PurposeThe purpose of this paper is to analyze the effect of collaboration, capability and information sharing (IS) on logistic performance, the effect of collaboration and IS on capabilities, the effect of collaboration on logistic performance through capabilities, the influence of IS on logistic performance through capabilities and the effect of logistics capabilities on logistics performance.Design/methodology/approachThis study uses a quantitative approach and is included in explanatory research. This research uses cross section research design. The research populations are all companies incorporated in GAFEKSI (Joint Forwarder and Expedition Indonesia) of East Java. Sampling in this research is by using a purposive sample. The sample of this study amounted to 47 forwarder and expedition companies. Data analysis method used is partial least square.FindingsCollaboration has a positive impact on capabilities (CAP); capability (LOC) positive impact on logistic performance; collaboration does not directly affect the logistics performance; and construct capabilities (LOC) is the mediation of IS in building business logistics performance. Increasing the intensity of IS has no direct contribution to increased flexibility, and collaboration is driven by partnership and network, whereas CT (trust) can be ignored, as it is not proven to make a dominant contribution to collaboration.Originality/valueThe novelty of this research is found in the strategic role of capabilities as the dominant latent variable in building business performance of logistic companies. This study finds dual mediation, where both mediations are expressed as full mediation, because the direct effect of mediator latent variables is significant (Little et al., 2010; Hair et al., 1995).
Assessing strategic social partnerships between professional sports teams and NPOs in Australian football
Authors: Rayne Daniel , McDonald Heath , Leckie Civilai 
Published: June 2019

PurposeThe purpose of this paper is to assess corporate social responsibility (CSR) implemented via social partnerships between professional sports teams and not-for-profit organizations according to current theoretical perspectives. Limited resources and outcomes often mean there is a gap between theory and practice, the implications of which are not well understood.Design/methodology/approachFive partnerships in Australian football were analyzed via case study methodology which incorporated interviews, analysis of websites, social media and annual reports.FindingsDespite being used as a CSR tool, findings showed most organizations enter these arrangements to achieve instrumental outcomes. Further, such partnerships mostly operate at a basic stage often described as philanthropic. One partnership was seen as more advanced consisting of a workplace plan to enhance diversity.Practical implicationsIt is advocated that managers adopt a more integrated partnership model consisting of formalized objectives, activity implementation, evaluation mechanisms, frequent interaction, top-level leadership involvement and promotion to sufficiently achieve CSR goals.Originality/valueAddressing calls from past research into an examination of the variation of CSR in sports, this research is one of the first to compare multiple case studies to assess the strategic implementation of social partnerships in a professional sporting context. Accordingly, the study demonstrates how such partnerships can be evaluated against a prominent theoretical model, the Collaboration Continuum, enabling more robust social partnership strategies.
Attitude: mediator of subjective norm, religiosity and intention to adopt Islamic banking
Authors: Bananuka Juma , Kasera Musa , Najjemba Grace Muganga , Musimenta Doreen , Ssekiziyivu Bob , Kimuli Saadat Nakyejwe Lubowa 
Published: June 2019

Purpose
The purpose of this paper is to report on the results of a study carried out to examine the mediating effect of attitude in the relationship between subjective norm, religiosity and intention to adopt Islamic banking in a developing secular state like Uganda.

Design/methodology/approach
This study’ research design was cross sectional. Closed ended questionnaires were distributed to 258 managers of micro businesses in Uganda. Data were analyzed with the help of SPSS v22 and MedGraph program (Excel version).

Findings
Attitude is a significant mediator in the relationship between subjective norm and intention to adopt Islamic banking. Also, attitude significantly mediates the relationship between religiosity and intention to adopt Islamic banking.

Research limitations/implications
The study used only a single research methodological approach; therefore, future research could be undertaken using a mixed-methods approach.

Practical implications
Emphasis should be put on improving the mindsets of Ugandans toward Islamic banking.

Originality/value
While there has been a number of studies on Islamic banking, this study provides an initial empirical evidence on the mediation effect of attitude in the relationship between subjective norm, religiosity and intention to adopt Islamic banking in a single study in an African developing secular state like Uganda.
Measuring perceptions of Muslim consumers toward income tax rebate over zakat on income in Malaysia
Authors: Al-Mamun Abdullah- , Haque Ahasanul , Jan Muhammad Tahir 
Published: June 2019

Purpose
The purpose of this study is to explore the variables that affect Muslim consumers’ perception towards tax rebate over zakat on income in Malaysia.

Design/methodology/approach
A close-ended structured questionnaire was developed and a total number of 236 valid responses were collected through online survey from the Muslims residing in Malaysia.

Findings
This study found that halal-haram aspect of Islamic Shariah, legal consciousness and religiosity of Muslim consumers are positive significant factors for growing perceptions towards tax rebate over zakat on income in Malaysia.

Research limitations/implications
This study will definitely play an important leading role for the policy-makers and academicians in understanding the perceptions of Muslim consumers.

Practical implications
This study can assist zakat and tax authorities in Malaysia for taking corrective actions to adapt or improve the current policy on the basis of its Muslim consumers’ perception.

Social implications
The findings of this study can reduce the gap of understanding among Muslims in the society by letting other people’s perceptions towards tax rebate through zakat system in Malaysia.

Originality/value
As there are not enough studies in this area, this study will definitely play an important leading role for the countries or policy-makers or concerned zakat or tax institutions all over the world in capitalizing the practices which is highly and positively perceived by the Muslim consumers in Malaysia.
Key audit matters: insight from audit experts
Authors: Segal Milton 
Published: June 2019

Purpose
Key audit matters (KAM) and their impact on the auditor is a relatively understudied area. The purpose of this study is to analyse whether auditors perceive that the recent requirement for auditors of listed companies to report KAMs has enhanced the transparency of audit reports or not, what additional risks they now face, how the risk is being managed and its impact on the relationship with their clients.

Design/methodology/approach
The paper uses an interpretive approach for detailed interviews with some of South Africa’s leading audit experts to highlight their perspective of the impact of KAM on audit reporting and the audit environment.

Findings
The experts have various perceptions of what makes a matter “key”. These vary from materiality, to subjectivity and difficulty, as well as incorporating a time-based consideration. Concerns identified include a significant increase in cost and an increase in potential liability, triggering the need for thorough internal risk management policies. The audit experts conclude that KAM has ultimately failed to achieve its goal of greater transparency, with clients virtually ignoring KAM reports.

Research limitations/implications
The research relies on a relatively small sample of subject experts and may not provide a complete account of the view of all audit professionals and KAM reports issued. It analyses the impact of KAM from the preparers’ perspective.

Originality/value
This study contributes to the research conducted in this topical area. Although there has been research on KAM focusing on pre-implementation consequences, there is virtually no formal academic research on the impact KAM has had on audit partners and firms in South Africa post implementation. It may also serve as a basis for the IAASB to consider going forward.