bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psoriatic Nail Dystrophy Is Associated with Erosive Disease in the Distal Interphalangeal Joints in Psoriatic Arthritis: A Retrospective Cohort Study
Authors: Antony Anna S. , Allard Andrew , Rambojun Adwaye , Lovell Christopher R. , Shaddick Gavin , Robinson Graham , Jadon Deepak R. , Holland Richard , Cavill Charlotte , Korendowych Eleanor , McHugh Neil J. , Tillett William 
Published: March 2019

Objective.To assess whether the association between psoriatic nail dystrophy and radiographic damage in the hands of patients with psoriatic arthritis (PsA) is specific to the distal interphalangeal (DIP) joints.Methods.A convenience sample of patients was collated from the Bath longitudinal PsA cohort. All patients had PsA according to the ClASsification for Psoriatic ARthritis criteria (CASPAR) criteria, scored radiographs of their hands, and documented nail scores as measured by the Psoriatic Nail Severity Score. Chi-square tests were performed to examine for association between features of nail dystrophy and radiographic damage in the DIP joints, and proximal interphalangeal or metacarpophalangeal (non-DIP) joints of the corresponding digits.Results.There were 134 patients included, with a median age of 53 years (interquartile range; IQR 44–61) and disease duration of 7 years (IQR 3–17). The presence of any form of psoriatic nail dystrophy was associated with erosion at the DIP joints of the corresponding digit (OR 1.9, 95% CI 1.23–2.83; p < 0.004) and this association was primarily driven by the presence of nail onycholysis (OR 1.72; 95% CI 1.12–2.62; p = 0.02). Nail subungual hyperkeratosis was more strongly associated with joint space narrowing, erosions, and osteoproliferation at the corresponding DIP joint compared to non-DIP joints (p < 0.001). Nail pitting was not associated with erosions or osteoproliferation.Conclusion.The presence of psoriatic nail dystrophy, particularly onycholysis, is associated with erosive disease at the DIP joints. Subungual hyperkeratosis is more strongly associated with erosive damage at the DIP than non-DIP joints. These findings support the anatomical and pathological link between nail and DIP joint disease.
The OMERACT Emerging Leaders Program: The Good, the Bad, and the Future
Authors: Flurey Caroline A. , Tugwell Peter S. , Black Rachel J. , Halls Serena , Page Matthew J. , Robson Joanna C. , Sahbudin Ilfita , Siddle Heidi J. , Sinnathurai Premarani , Stok Kathryn S. , Richards Bethan 
Published: March 2019

Objective.To describe the experience of the first OMERACT Emerging Leaders Program (ELP).Methods.A Delphi process identified positive aspects, areas for improvement, and future directions. Core items were defined as essential if they received ≥ 70% ratings.Results.Participants valued relatable/accessible mentors (100%), including an OMERACT Executive mentor (100%), and a support network of peers (90%). Key items for future development were funding support (100%) and developing knowledge about OMERACT processes (90%) and politics (80%).Conclusion.The ELP has the potential to provide targeted training for early career researchers to develop relevant skills for future leadership roles within OMERACT.
Measuring Reliability of Movement With Accelerometry: Fitbit® Versus ActiGraph®
Authors: Rowe Veronica T. , Neville Marsha 
Published: March 2019

Abstract
OBJECTIVE. We sought to determine the reliability of the Fitbit® Flex™ compared with the ActiGraph® Bluetooth® Smart wGT3X-BT wireless activity monitor and to contribute to the clinical utility of accelerometry measurement of upper extremity (UE) movement.
METHOD. Two studies were conducted at different sites with healthy adult participants. In Study 1, participants wore both accelerometers on both wrists during everyday activities for a 24-hr period. In Study 2, participants wore both accelerometers on the dominant wrist for 4 hr during an active period of the day. All participants wore the accelerometers during regular daily activities.
RESULTS. Data recorded from the Fitbit and the ActiGraph showed a high positive correlation; however, the Fitbit recorded significantly fewer movements than the ActiGraph.
CONCLUSION. Although the Fitbit and the ActiGraph measure UE activity similarly, the Fitbit was not as sensitive as the ActiGraph. This study provides informative data on the clinical utility of the Fitbit compared with the ActiGraph.
Dual-wavelength radar technique development for snow rate estimation: a case study from GCPEx
Authors: Huang Gwo-Jong , Bringi Viswanathan N. , Newman Andrew J. , Lee Gyuwon , Moisseev Dmitri , Notaroš Branislav M. 
Published: March 2019

Abstract. quantitative precipitation estimation (QPE) of snowfall has generally been
expressed in power-law form between equivalent radar reflectivity factor
(Ze) and liquid equivalent snow rate (SR). It is known that
there is large variability in the prefactor of the power law due to changes
in particle size distribution (PSD), density, and fall velocity, whereas the
variability of the exponent is considerably smaller. The dual-wavelength
radar reflectivity ratio (DWR) technique can improve SR
accuracy by estimating one of the PSD parameters (characteristic diameter),
thus reducing the variability due to the prefactor. The two frequencies
commonly used in dual-wavelength techniques are Ku- and Ka-bands. The basic
idea of DWR is that the snow particle size-to-wavelength ratio is
falls in the Rayleigh region at Ku-band but in the Mie region at
Ka-band. We propose a method for snow rate estimation by using NASA D3R radar DWR and
Ka-band reflectivity observations collected during a long-duration synoptic
snow event on 30–31 January 2012 during the GCPEx (GPM Cold-season
Precipitation Experiment). Since the particle mass can be estimated using
2-D video disdrometer (2DVD) fall speed data and hydrodynamic theory, we
simulate the DWR and compare it directly with D3R radar measurements. We also use
the 2DVD-based mass to compute the 2DVD-based SR. Using three different mass
estimation methods, we arrive at three respective sets of Z–SR and
SR(Zh, DWR) relationships. We then use these relationships with D3R
measurements to compute radar-based SR. Finally, we validate our method by
comparing the D3R radar-retrieved SR with accumulated SR directly measured by a
well-shielded Pluvio gauge for the entire synoptic event.
Denoising stacked autoencoders for transient electromagnetic signal denoising
Authors: Lin Fanqiang , Chen Kecheng , Wang Xuben , Cao Hui , Chen Danlei , Chen Fanzeng 
Published: March 2019

Abstract. The transient electromagnetic method (TEM) is extremely important in geophysics.
However, the secondary field signal (SFS) in the TEM received by coil is easily
disturbed by random noise, sensor noise and man-made noise, which results in
the difficulty in detecting deep geological information. To reduce the noise
interference and detect deep geological information, we apply autoencoders, which
make up an unsupervised learning model in deep learning, on the basis of the analysis of the
characteristics of the SFS to denoise the SFS. We introduce the SFSDSA (secondary
field signal denoising stacked autoencoders) model based on deep neural networks of
feature extraction and denoising. SFSDSA maps the signal points of the noise
interference to the high-probability points with a clean signal as reference
according to the deep characteristics of the signal, so as to realize the
signal denoising and reduce noise interference. The method is validated by the
measured data comparison, and the comparison results show that the noise
reduction method can (i) effectively reduce the noise of the SFS in contrast with the
Kalman, principal component analysis (PCA) and wavelet transform methods and (ii) strongly support the
speculation of deeper underground features.
ESTADO NUTRICIONAL EN ESCOLARES DE PRIMERO A SEXTO GRADO EN LA PAZ, HONDURAS
Authors: Delcid Morazán Allan Fernando , Delcid Morazán Luis Enrique , Barcan Batchvaroff Moran E , Leiva Molina Fabricio Alfonso , Barahona Andrade Delmy Soraya 
Published: March 2019

Un estado nutricional deficiente en la niñez incrementa el riesgo de muerte, inhibe su desarrollo cognitivo y afecta su estado de salud de por vida. Atender esta condición es indispensable para asegurar el desarrollo de la niñez y garantizar el desarrollo del país. Objetivo: Establecer el estado nutricional en niños escolares de seis a doce años que asisten a la escuela “Nuestra Señora la Merced”, La Paz, Honduras, durante el período de marzo - abril de 2016. Metodología: Estudio descriptivo de corte transversal, universo de 155 niños de primero a sexto grado, muestra 110 niños, índice de confianza 95%, probabilidad a favor 50% y porcentaje de error 5%. Previo consentimiento informado autorizado por tutores le- gales. Se utilizaron las tablas y guías de la OMS para valorar el estado nutricional de los niños. Resultados: De 110 estudiantes evaluados: 11 (10%) estaban emaciados, 6 (5%) obesos, 14 (13%) sobrepeso, 21 (19%) posible riesgo de sobrepeso, 58 (53%) tenían un adecuado estado nutricional. De los niños emaciados; 40% habían padecido enfermedades respiratorias, 30% chikungunya, 10% diarrea y 10% anemia. En todos los hogares de los niños emaciados los padres reciben un ingreso mensual menor al salario mínimo. Conclusiones: Los trastornos nutricionales siguen presentes en la niñez hondureña, con un aumento significativo de niños en posible riesgo de sobrepeso y obesidad, siendo estos los principales problemas en la actualidad de los escolares en nuestro estudio, sin embargo, todavía existen niños con emaciación.
Palabras clave
Desarrollo infantil, Desnutrición, Obesidad
DIAGNOSTICO RADIOLOGICO DE LESIONES LUMBARES EN LA ZONA NOR-OCCIDENTAL DE HONDURAS 2014 – 2016
Authors: González Pieri Manuel , Handal Astrid , Licona Diana , Suazo Michelle , Villeda Paula , Rivera Yohely 
Published: March 2019

El dolor lumbar se define como un síndrome musculoesquelético cuyo principal síntoma es la presencia de dolor focalizado en el área comprendida entre la región costal inferior y la región sacra, y que en ocasiones puede comprometer la región glútea, provocando disminución funcional. Objetivo: Identificar las lesiones lumbares diagnosticadas por medio de estudio radiográfico de columna lumbar. Pacientes y Métodos: Estudio descriptivo, retrospectivo, comprendido entre 2014 y 2016, en los pacientes que asistieron a Mediscan para la realización de estudio radiográfico de columna lumbosacra con una muestra de 687 pacientes. Resultados: De los 687 pacientes, 309(44.9%) del género masculino, 378(55.1%) del género femenino. 211 tenían entre 51-60 años. De los pacientes del género masculino 103 (33.33%) tenían espondiloartrosis y 63 (20.39%) tenían canal espinal estrecho, en el género femenino 162 (42.86%) tenían espondiloartrosis, 83(21.96%) discopatía lumbar. En 562 pacientes, se encontró lesión en el estudio radiológico, 264(46.9%) a nivel de L4- L5 Conclusión: La lumbalgia se presenta más en pacientes del género femenino, con mayor frecuencia entre 51-60 años. La patología más diagnosticada fue la espondiloartrosis y el segmento más afectado fue L4-L5.
Palabras clave
Columna vertebral, Color de la región lumbar, Espondiloartritis, Fractura
CONSUMO DE ALCOHOL ENTRE ESTUDIANTES DE MEDICINA QUE CURSAN ASIGNATURAS DE FARMACOLOGIA I Y II
Authors: Gómez Vilma , Reyes Mario , Galo Pablo , Euceda Jeancarlo , Agurcia Lissandro , Licona Iveth , Andrade Mancías Lourdes Azucena 
Published: March 2019

Antecedentes: El alcohol es considerada una droga que tiene repercusión negativa en la vida del individuo consumidor activo o no. El consumo de alcohol es multifactorial y preocupa en jóvenes universitarios por ser una droga de fácil acceso, barato y con menos estigma a nivel social. Objetivo: Describir y comparar el consumo de alcohol en estudiantes de medicina hombres y mujeres que cursan las asignaturas de Farmacología I y II el primer semestre del año 2017 en la Escuela Universitaria de Ciencias de la Salud en la Universidad Nacional Autonoma de Honduras en el Valle de Sula (EUCS/ UNAH-VS). Pacientes y métodos: Estudio cuantitativo, alcance descriptivo. Población: muestra por conveniencia de 56 estudiantes (28 mujeres y 28 hombres). Se utilizó un instrumento tipo cuestionario para la recolección de datos, previo consentimiento informado. Resultados: El 73%. (41) consumía alcohol. Los resultados revelaron mayor consumo en mujeres 43% (24) que en hombres 30% (17). Un 36.7% (20) refiere la ingesta de alcohol en vacaciones y 26.8% (15) después de exámenes. Un 98% (55) conocían de los efectos nocivos del alcohol. Conclusiones: El consumo de alcohol es una práctica en los jóvenes universitarios de las asignaturas de Farmacología I y II. Un alto porcentaje de los estudiantes partícipes de éste estudio ha consumido alcohol, la mayoría lo hace ocasionalmente. El consumo es mayor por parte de las mujeres. La sustancia más consumida es la cerveza (ambos sexos). La mayoría conoce los efectos nocivos del alcohol, pero no los detiene a consumirlo.

Palabras clave
Alcohol, Estudiante universitario, Sustancias nocivas
Niedzwiedzia Przysluga?Bear’s Favor? Hidden Garden behind the Concrete Proverbs: Cognitive-Semantic Analysis of Proverbs in Persian, Polish and Spanish
Authors: Singh Rajdeep 
Published: March 2019

Proverbs help us understand how the society works at large and what are the main concerns regarding the environment, people-to-people exchange and notions of liberty, freedom and values. In some cultures such as the Iranian one, the way one uses proverbs depends on the generation one finds herself in. Generation-gap provides opportunity to transfer some abstract and complicated concepts, not available in modern life, through the use of proverbs. From childhood, by hearing proverbs from parents and grand-parents, children begin grasping some important national and even religious concepts. In order to represent a rather international, holistic view and not language-specific, we analyzed further Polish, French and Spanish proverbs, whenever deemed necessary. The present paper through cognitive-semantic and content analysis aims to reveal the implied systems of value, ethics and morality realized through proverbs. The results clearly indicate that proverbs cover different systems of values through elements such as artifacts, animals, human body parts and even imaginary, nature-derived elements.
Characterization of Business Models by the Logic of Transaction Cost Economics
Authors: Moreira de Oliveira Hugo , Messias Rossi Ricardo , Caetano de Souza Mauro 
Published: March 2019

Objetivo (obrigatório): O presente estudo tem por objetivo caracterizar os modelos de negócios sob a lógica das estruturas de governança discutidas na Economia dos Custos de Transação (ECT). Método (obrigatório): A partir da revisão na literatura, foram identificados os principais elementos que compõem um modelo de negócios, que foram então combinados em um modelo gráfico com as principais características da Economia dos Custos de Transação (ECT) adotadas. Originalidade/Relevância (obrigatório): Com base na fundamentação teórica sobre o assunto, foi identificada a forma com que os elementos de um modelo de negócios interagem entre si, sob a lógica da ECT. Resultados (obrigatório): Os resultados apresentam as relações entre os componentes de um modelo de negócio e as principais características conceituais da ECT. Um modelo de negócio é suportado por elementos como as especificidades dos ativos, frequências e incertezas, estratégias de diferenciação, entre outros, definidos a partir da segmentação de clientes. Contribuições teóricas/metodológicas (obrigatório): As principais contribuições estão relacionadas à complementaridade da literatura sobre modelos e negócios, em seus diferentes elementos, à luz da ECT de modo a caracterizar a competitividade de diferentes organizações, a partir de diferentes estratégias adotadas. Contribuições sociais / para a gestão (opcional): Diferentes organizações, que já se pautam na redução dos custos transacionais, podem se utilizar dos elementos que caracterizam um modelo de negócio para se tornarem mais competitivas. Palavras-chave: Competitividade Organizacional; Estratégia; Estrutura de Governança.
História de vida laboral e aposentadoria: uma metodologia em discussão
Authors: Carreteiro Teresa Cristina 
Published: March 2019

O texto aborda a historia de vida na perspectiva da psicossociologia. Em um primeiro tempo discute aspectos primordiais para que a realização deste trabalho possa ocorrer: o engajamento do participante, do profissional e a escuta clinica plural. Em um segundo tempo enfoca a historia de vida laboral na vertente da narrativa da aposentadoria. A hipótese é que a aposentadoria constitui uma ruptura na trajetória de vida e sugere que o advento deste momento requer um olhar atento à historia de vida laboral.
Desafios na construção de ferramentas de impacto social
Authors: Quintão Frederico Dornellas 
Published: March 2019

A conhecida lei de cotas nº 8.213 promulgada em 1991 tem a função de garantir o direito da pessoa com deficiência (PCD) ao acesso no mercado de trabalho. Entretanto, devido a preconceito ou negligência, essa inclusão é deficitária. Motivo pelo qual muitas das ações afirmativas de direitos da PCD decorrem de ações e projetos sociais protagonizadas pela sociedade civil organizada. Esses projetos do terceiro setor tem como objetivo equilibrar as diferenças sociais na dinâmica coletiva e necessitam de instrumentos que mensurem e validem com qualidade o tipo de impacto alcançado. No entanto, a avaliação de impacto social ainda é um grande desafio, uma vez que é preciso identificar se houve também outros impactos não previstos produzidos durante o caminho, dada a complexidade das variáveis de uma intervenção social. Nesse contexto, o presente artigo busca elucidar os desafios de se construir um seguro portfólio de ferramentas de avaliação de impacto social, a partir do estudo de caso do programa Rede Incluir, da Pró Reitoria de Extensão (PROEX) da Pontifícia Universidade Católica de Minas Gerais (PUC-MG). Utilizando os preceitos de Impacto Social das Nações Unidas e as diretrizes da Organização Mundial de Saúde no que diz respeito a PCD, elegemos como indicadores mais relevantes os Índices de Qualidade de Vida, Funcionalidade e Empregabilidade. Parte-se da hipótese de que, uma vez aplicado tais instrumentos, seja possível monitorar o desenvolvimento das pessoas com deficiência atendidas pelo programa e identificar dificuldades e potencialidades individuais ou coletivas, a fim de possibilitar um atendimento personalizado, inclusivo e integrado às estratégias gerais elaboradas pela Rede Incluir
Prevalência do estado nutricional de crianças institucionalizadas e fatores associados
Authors: Da Silva Maitê Costa , De Oliveira Thais Souza Chaves , Capanema Flávio Diniz , Lamounier Joel Alves , Lisboa Pereira Simone Cardoso , De Lima Costa Bruna Vieira , Gaete Perez Ana Maria 
Published: March 2019

Objetivo: Determinar a prevalência da desnutrição e obesidade em crianças de creches públicas de Belo Horizonte-MG em umperíodo de sete anos 2005-2011.Métodos: Foi realizado um estudo de corte transversal nos anos 2005 e 2011, sendo avaliadas crianças de crehces públicas de seis a 72 meses do Distrito Sanitário Leste de Belo Horizonte-MG. O estado nutricional foi avaliado de acordo com a Organização Mundial da Saúde - OMS (2006/2007). Fatores socioeconômicos e de saúde foram avaliados pelo emprego de um questionário aos pais/responsáveis pelas crianças. As análises estatísticas foram realizadas por meio do software R. versão 2.15.3. Resultados: A prevalência do estado nutricional das crianças apresentou um aumento da obesidade em todas as variáveis analisadas, nos anos avaliados. Dentre os fatores avaliados os que apresentaram influência no estado nutricional foram: faixa etária, com quem a criança mora, o peso ao nascimento e o tipo de parto.Conclusão: A prevalência da desnutrição e obesidade revelou a ocorrência do aumento da prevalência de obesidade nas crianças das creches avaliadas.
Evaluation of Calcium Homeostasis and Dietary Supplementation for Pediatric and Neonatal Patients Receiving Extracorporeal Membrane Oxygenation Support
Authors: Kaplan Marcus C. , Heath Travis S. 
Published: March 2019

OBJECTIVES Although the use of extracorporeal membrane oxygenation (ECMO) significantly improves survival in patients with persistent respiratory or cardiovascular failure, it also induces physiologic stress and disrupts homeostatic mechanisms. Patients undergoing ECMO support at our institution have required widely variable quantities of calcium supplementation for maintenance of normal calcium levels. Our primary objective was to assess the frequency of calcium abnormalities in pediatric and neonatal ECMO patients. Secondary objectives included quantifying electrolyte supplementation provided during ECMO and determining the relationships between calcium abnormalities and ECMO duration, mortality, and intensive care and hospital length of stay.
METHODS We performed a single-center retrospective chart review of all patients less than 18 years of age who received ECMO support between July 1, 2013, and May 31, 2016. Clinical and laboratory data were reviewed for each patient for the duration of ECMO support, and the incidence of ionized calcium outside the reference range of 1.1 to 1.4 mmol/L beyond the first 24 hours of ECMO was recorded.
RESULTS Seventy-eight patients were included in the study: 51 patients (65%) experienced at least one reading outside the normal ionized calcium range, while 27 patients (35%) were normocalcemic during their ECMO course. There were no differences between groups in the quantities of calcium, phosphate, or vitamin D administered during ECMO. Abnormal calcium levels were associated with a longer duration of ECMO (median 9 days vs 6 days, p = 0.0054), prolonged ICU length of stay (median 33 vs 18 days, p = 0.0055), and prolonged hospital length of stay (median 52 vs 40 days, p = 0.0239). No significant differences were found in survival to decannulation or survival to hospital discharge.
CONCLUSIONS Calcium abnormalities occur frequently in pediatric and neonatal patients during ECMO and are associated with worse patient outcomes. The underlying physiology of these changes is thought to be related to ECMO-induced disruption of normal calcium homeostasis.