bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nanoplatforms for Magnetic‐Photo‐Heating of Thermo‐Resistant Tumor Cells: Singular Synergic Therapeutic Effects at Mild Temperature
Authors: Mai Binh T. , Fernandez‐Cabada Tamara , Conteh John S. , Nucci Giulia E.P. , Fiorito Sergio , Gavilán Helena , Debellis Doriana , Gjurgjaj Lorenci , Pellegrino Teresa 
Published: October 2024

AbstractA self‐assemble amphiphilic diblock copolymer that can incorporate iron oxide nanocubes (IONCs) in chain‐like assemblies as heat mediators for magnetic hyperthermia (MHT) and tuneable amounts of IR780 dye as agent for photothermal therapy (PTT) is developed. MHT‐heating performance of photobeads in viscous media have the same heat performances in water at magnetic field conditions of clinical use. Thanks to IR780, the photobeads are activated by infrared laser light within the first biological window (808 nm) with a significant enhancement of photo‐stability of IR780 enabling the raise of the temperature at therapeutic values during multiple PTT cycles and showing unchanged optical features up to 8 days. Moreover, the photobeads fluorescent signal is preserved once internalized by glioblastoma multiforme (GBM) cells. Peculiarly, the photobeads are used as toxic agents to eradicate thermo‐resistant GBM cells at mild heat, as low as 41 °C, with MHT and PTT both of clinical use. Indeed, a high U87 GBM cell mortality percentage is obtained only with dual MHT/PTT while each single treatment dose not provide the same cytotoxic effects. Only for the combined treatment, the cell death mechanism is assigned to clear sign of apoptosis as observed by structural/morphological cell studies and enhanced lysosome permeability.
Boosting Photoluminescence of Rare‐Earth‐Based Double Perovskites by Isoelectronic Doping of ns2 Metal Ions
Authors: Yao Jiandong , Wang Haiyan , Wu Jie , Zou Bingsuo , Zeng Ruosheng 
Published: October 2024

AbstractDoping of ns2 metal ions as an energy transfer (ET) bridge can significantly elevate the photoluminescence properties. Nonetheless, the fundamental influence of ns2 metal ions on the local lattice structures remains unclear, hindering the advancement of functional materials. Herein, Sb3+ doped rare earth double perovskites is employed as a typical case to demonstrate this issue. It is found that the isoelectronic doping of Sb3+ ions not only enhances the ET efficiency but also changes their localized electronic and lattice structures. Both density functional theory (DFT) and Judd–Ofelt (J–O) theory calculations provide unambiguous evidence that the isoelectronic doping of Sb3+ ions enables a more localized charge density in the [LnCl6]3− (Ln: Lanthanide) octahedron and reduces the symmetry of the environment around the Ln3+, facilitating the radiative transition rates of Ln3+ while enhancing their ET efficiency. Compared with Cs2NaScCl6:Ln3+, the ET efficiency of Cs2NaScCl6:Sb3+/Ln3+ is enhanced by 1.5‐fold, reaching up to 98.3%. To the best of available knowledge, this work is the first to unravel the intrinsic mechanism of enhanced ET process enabled by isoelectronic doping via DFT and J–O theory. This research sheds light on understanding the mechanism of photophysics and rational design of the functional perovskite materials.
Rational Design of Ultrahigh‐Loading Ir Single Atoms on Reconstructed Mn─NiOOH for Enhanced Catalytic Performance in Urea‐Water Electrolysis
Authors: Ngo Quynh Phuong , Prabhakaran Sampath , Kim Do Hwan , Kim Byoung‐Suhk 
Published: October 2024

AbstractInvestigating advanced electrocatalysts is crucial for improving the efficacy of water splitting to generate environmentally friendly fuel. The discovery of highly effective electrocatalysts, capable of driving oxygen evolution reaction (OER) and urea oxidation reaction (UOR) in urea‐alkaline environments, is pivotal for advancing large‐scale hydrogen production. This study aims to introduce a new method that involves creating nanosheets of high‐loading iridium single atoms embedded in a manganese‐containing nickel oxyhydroxide matrix (Ir@Mn─NiOOH). These nanostructures are derived from self‐supported hydrate pre‐catalyst nanosheets grown on nickel foam and then activated through electrochemical etching pretreatment. The Ir@Mn─NiOOH nanoarchitecture displays outstanding electrocatalytic activity, having a low overpotential of just 258 mV and a potential of 1.319 V (at 10 mA cm−2) for OER and UOR, respectively. Such extraordinary catalytic characteristics of Ir@Mn─NiOOH is mainly owing to the strong synthetic electronic interaction between Ir single atoms and Mn─NiOOH, which can change its electronic characteristics and boost electrochemical catalytic sites. This research presents a new way to produce exceptionally efficient catalysts by adding a synergistic effect to complex multi‐electron processes.
SbO(OH)2(IO3): The First Polar Sb5+‐Iodate with a Strong Second‐Harmonic Generation Response and a Wide Bandgap
Authors: Ji Meng‐Ya , Li Yi‐Lin , Hu Chun‐Li , Chen Jin , Li Bing‐Xuan , Mao Jiang‐Gao 
Published: October 2024

AbstractWidening the bandgaps while maintaining a strong second harmonic generation response has always been a research hotspot in the field of nonlinear optical iodate materials. A strategy involving covalent bonding is proposed that leverages the high valent later main group cation to construct iodates with predominantly covalent interactions. By using BiO(IO3) as a template, the first Sb5+‐containing polar iodate, SbO(OH)2(IO3) is successfully isolated. The introduction of the two hydroxide anions led to the reduction of layered BiO(IO3) into 1D SbO(OH)2(IO3) in which two corner‐sharing SbO4(OH)2 octahedra are further bridged by an iodate group. The covalently bonded [SbO(OH)2]+ chains and the optimal packing fashion of the asymmetric IO3− groups generate a very strong second harmonic generation signal of 14 times that of KH2PO4. Furthermore, SbO(OH)2(IO3) exhibits a wide bandgap of 4.14 eV and a high laser induced damage threshold [27.9 × AgGaS2, 0.2 × KH2PO4 (10 ns, 10 Hz)].
Chemical Bath Deposition of NiFe Alloy Anode for Efficient Alkaline Water Electrolyzer Integration
Authors: Wu Jingwen , Ren Zhibo , Xu Xindi , Mok Dong Hyeon , Guo Weiqi , Ye Ke , Shen Peng , Zhang Weiyi , Ni Baoxin , Wan Shusheng , Yu Gwonho , Cai Wen‐Bin , Back Seoin , Wang Jinyi , Jiang Kun 
Published: October 2024

AbstractGreen hydrogen production from water splitting is a feasible way for intermittent renewable energy storage and utilization, where the exploration and scale‐up preparation of high‐performance anodic oxygen evolution electrocatalysts are critical prerequisites for its industrial‐level applications. Herein, a chemical bath deposition of FeNi3 intermetallic alloys onto Ni mesh support is performed, which delivers a current density of 0.62 A cm−2 at 1.72 V versus reversible hydrogen electrode for alkaline water oxidation in 1 m KOH and an excellent electrolysis stability at 0.2 A cm−2 for over 300 h. Moreover, via 3D computational fluid dynamics simulation and flow field optimization, a homogeneous deposition of ≈5400 cm2 NiFe anode is demonstrated within 4 min using the developed flow bath reactor. Once integrating the as‐prepared NiFe anodes into alkaline electrolyzer stack, the voltage variation between each unit cell is below 40 mV at a total operation current of 71 A, or ca. current density of 0.2 A cm−2, confirming the uniformity of this batch synthesis protocol and its great potential for industrial alkaline water electrolysis.
Fully Stretchable Microbial Fuel Cell with 75% Stretchability
Authors: Peng Shizhe , Li Jia , Hu Yihan , Cao Jinwei , Zhou Ming , Lu Lu , Su Yude 
Published: October 2024

AbstractA decent stretchability is of paramount significance to operate microbial fuel cell (MFC) under mechanically dynamic conditions. However, it remains a grand challenge to fabricate fully stretchable MFC without compromising its power output. Here, using Shewanella oneidensis MR‐1 (S. oneidensis) as the model electrogenic bacteria, the study demonstrates a fully stretchable MFC device that can operate with a stretchability of 75%. The design takes advantage of a stretchable and ion‐conductive polyurethane membrane, which encapsulates the biohybrids composed of S. oneidensis and reduced graphene oxide (rGO) on the polydimethylsiloxane (PDMS) current collector for synchronous stretching. It is discovered that the “stretchable” living biohybrids can sustain an adaptive bio‐current output under stretching/releasing stimulation. The design also employs a stretchable air cathode. The stabilized peak power density of the stretchable MFC follows an increasing trend with the applied strain, and reaches 5.0 ± 0.7, 5.9 ± 0.9, 6.2 ± 1.1, 6.6 ± 1.4 µW cm−2 at strains of 0%, 25%, 50%, and 75%, respectively (n = 3). At 75% strain, the stretchable MFC yields a maximum current output of 104 ± 27 µA cm−2 and an open‐circuit voltage of 283 ± 30 mV (n = 3). The results provide insights to design stretchable MFCs to power the next‐generation on‐skin devices, soft robotics, and sustainable electronics.
Bioinspired Photothermal Metal‐Organic Framework Cocrystal with Ultra‐Fast Water Transporting Channels for Solar‐Driven Interfacial Water Evaporation
Authors: Wang Xu , Zhao Chong , Yang Mingyu , Baek Jae‐Hoon , Meng Zheng , Sun Bin , Yuan Aihua , Baek Jong‐Beom , He Xiao , Jiang Yi , Zhu Meifang 
Published: October 2024

AbstractHerein, a bioinspired metal‐organic framework (MOF) cocrystal produced from the co‐assembly of a MOF [Ni3(hexaiminobenzene)2, Ni3(HIB)2] and p‐chloranils (CHLs) is reported. Because of the 2D conjugation nature and the formation of persistent anion radicals, this cocrystal shows an excellent photothermal property, and is further used as an absorber in solar‐driven interfacial water evaporation. The solar‐driven interfacial water evaporation rate (4.04 kg m−2 h−1) is among the best compared with those of previously reported photothermal materials. Molecular dynamics simulation results suggested that the rotating of the CHL molecules relative to the MOF planes tuned the pore size to enable the ultra‐fast water transporting, and thus ultra‐high water transporting rates (1.11 × 1011 and 3.21 × 1011 H2O s−1 channel−1 at 298.2 and 323.0 K, respectively) for layered cocrystal structures, that are much higher than that of aquaporins (≈1.1 × 1010 H2O s−1 channel−1 at 298.2 K), are observed. The superior solar‐driven water evaporation performance is thus attributed to the synergistic effect of the ultra‐fast water transporting pores together with the excellent photothermal property of the cocrystal. This research provided a biomimetic strategy of rational design and production of charge transfer cocrystals to modulate their pores and photothermal properties for solar‐driven interfacial water evaporation.
The uniqueness and importance of small institutions in America
Authors: Johnson R. Bradley , McGhee James , Robertson Jason 
Published: October 2024

AbstractThe authors examine the unique and important role of small institutions in the landscape of higher education in the United States. Through an examination of student success, community engagement, and sense of belonging, the authors aim to provide a better understanding of the evolving dynamics in small institutions and the need for bold institutional leaders to retain institutional distinctiveness while innovating and redesigning the student experience for the 21st century.
Small institutions with special missions through the lens of women's colleges
Authors: Butera Rae‐Anne 
Published: October 2024

AbstractThe universe of small institutions includes “special mission” institutions. Although these institutions share several similarities, each plays a special and distinct role in higher education, providing a unique culture and experience for their students. They include women's colleges, Historically Black colleges and universities (HBCUs), Hispanic‐serving institutions (HSIs), Tribal colleges and universities (TCUs), faith‐based institutions, and military colleges, among others. Through the lens of women's colleges, the author will highlight these institutions and their important role in higher education.
Exploring student engagement and sense of belonging at small institutions post COVID‐19 pandemic
Authors: Lopez Samantha N. 
Published: October 2024

AbstractThis article explores the dynamics of student engagement in small institutions, emphasizing their unique community‐centered approach. Particularly in the post‐pandemic era, where personalized support systems have become crucial, small institutions are reevaluating their strategies to enhance student empowerment and connection. Key aspects examined include tailored academic advising, mental health services, and career guidance, all pivotal in fostering holistic student development. The article explores critical factors influencing engagement, such as institutional support, campus culture, and the integration of technological advancements, highlighting how these elements contribute to a vibrant learning environment in small institutions.
Gingival mesenchymal stem cells derived from patients with rheumatoid arthritis treat experimental arthritis
Authors: Hou Yuluan , Zhang Ximei , Zeng Donglan , Zhu Shangling , Luo Yang , Dang Junlong , Wu Wenbin , Xiong Yiding , Zhao Jun , Huang Jianlin , Yuan Jia , Wang Shuhong , Wang Julie , Xu Hanshi , Zhang Wei , Ai Hong , Chen Zheng , Zheng Song Guo 
Published: October 2024

AbstractA therapeutic strategy using mesenchymal stem cells (MSCs) has been accepted as a novel therapy for treating rheumatoid arthritis (RA). Human gingiva‐derived MSCs (GMSCs) are superior in regulating immune responses. Autologous MSCs are the optimal candidate to avoid the potential risks of allogenic MSCs. However, whether autologous GMSCs from RA patients are therapeutic remains unknown. In this study, we compared the therapeutic efficacy of GMSCs derived from patients with RA (RA‐GMSCs) and that from health donors (H‐GMSCs) in vivo and in vitro. Then, we utilized RNA‐sequencing, the molecular and cellular assays to determine the immunomodulatory molecules that contribute to the therapeutic effect of RA‐GMSCs on both collagen‐induced arthritis (CIA) and humanized synovitis models. We demonstrated that GMSCs derived from patients with RA (RA‐GMSCs) and health donors (H‐GMSCs) shared a similar expression of immunomodulatory molecules. Moreover, RA‐GMSCs were as effective as H‐GMSCs in suppressing T‐cell proliferation, proinflammatory cytokines secretion, as well as osteoclast differentiation in vitro. In addition, RA‐GMSCs had a robust therapeutic effect on the CIA model. Importantly, RA GMSCs can survive for at least 24 days in a CIA mouse model and can be distributed in the spleen, lymph nodes, and joints. Specifically, RA‐GMSCs decreased the frequency of Th1 and Th17 cells whereas enhanced Treg cells, reducing the joint histopathological scores of lymphocytes, osteoclasts, and cartilages. Moreover, RA‐GMSCs were also effective in suppressing inflamed synoviocyte proliferation, migration, and invasion in vitro, and cartilage invasion in a humanized synovitis model in vivo. Our study implies that manipulation of RA‐GMSCs is therapeutic in CIA mice and humanized synovitis models and may have therapeutic potential in RA patients using autologous GMSCs in the future.
The Role of Labor Markets in Determining the Efficacy and Distributional Impact of Sustainability Policies
Authors: Ray Srabashi , Haqiqi Iman , Hill Alexandra E. , Taylor J. Edward , Hertel Thomas W. 
Published: October 2024

AbstractLocal labor market outcomes are often overlooked in integrated assessment models. Yet labor markets have become increasingly relevant in recent decades as evidence of diminished labor mobility has emerged in the United States and other developed countries. We use the SIMPLE-G modeling framework to investigate the impacts of a global commodity price shock and a local sustainable groundwater use policy in the United States. We compare the impacts of each of these shocks under two contrasting assumptions: perfect mobility of agricultural labor and relatively inelastic labor mobility. We supplement the numerical simulations with analytical results from a stylized two-input model to provide further insights into the impacts of local and global shocks on agricultural labor, crop production, and resource use. In the perfect labor mobility scenario, the impact of a commodity price boom is overestimated relative to the restricted labor mobility case. In the case of groundwater sustainability policy, the perfect labor mobility scenario overestimates the reduction in crop production and employment in directly targeted grids as well as overestimates the spillover effects that increase employment in other grids. For both shocks, impacts on agricultural wages are completely overlooked if we ignore rigidities in agricultural labor markets.
The Role of Transportation Infrastructure Expansion in the Transmission of Global Crop Price Shocks to the Brazilian Agriculture
Authors: Wang Zhan 
Published: October 2024

AbstractIn this chapter, we discuss how crop production, land use, and carbon emissions in Brazil are influenced by the interaction of a global crop price shock with domestic transportation infrastructure investments. The grid-resolving feature of SIMPLE-G-Brazil provides a framework for simulating impacts from multiscale shocks and capturing the spatial heterogeneity and spillover effects of results within the country. First, we illustrate this research question with a simplified two-region economic framework, which provides qualitative implications of the interactive effects to be checked with SIMPLE-G-Brazil. Then, we introduce the model structure and data sources used in SIMPLE-G-Brazil and focus on the two new modules—a transportation cost module and a novel cropland supply module—that differentiate SIMPLE-G-Brazil from the basic SIMPLE-G framework. Simulation results indicate that farm-gate crop prices increase in response to an increase in global crop prices, boosting cropland and crop output. However, the rise in farm-gate crop prices hinges on the transportation cost from the farm to the port. Public investment in transport infrastructure reduces these costs, particularly for more remote locations. This reconfiguration of production has important implications for the environment.
Future Directions: Policy Implications, Model Extensions, and Institutional Innovation
Authors: Haqiqi Iman , Hertel Thomas W. , Wang Zhan , Baldos Uris Lantz C. , Cisneros-Pineda Alfredo , Liu Jing 
Published: October 2024

AbstractThis chapter lays out some future opportunities for the SIMPLE-G community. We envision a global community of researchers collaborating on data, modeling, and policy applications at the local, national, and global levels. The SIMPLE-G framework can be linked to gridded models from other disciplines, including agronomy, climate science, hydrology, ecology, and geography. By developing versions that allow for bilateral trade, multiple crops, and linkages to the rest of the economy, SIMPLE-G will also become relevant to a wider range of policy questions. We invite users to engage with the SIMPLE-G community and help advance this research to support efforts aimed at ensuring long-run land and water sustainability for the planet.
Leptogenesis in SO(10) with minimal Yukawa sector
Authors: Babu K. S. , Di Bari Pasquale , Fong Chee Sheng , Saad Shaikh 
Published: October 2024

Abstract
In prior studies, a very minimal Yukawa sector within the SO(10) Grand Unified Theory framework has been identified, comprising of Higgs fields belonging to a real 10H, a real 120H, and a $$ {\overline{126}}_H $$

126
¯

H

dimensional representations. In this work, within this minimal framework, we have obtained fits to fermion masses and mixings while successfully reproducing the cosmological baryon asymmetry via leptogenesis. The right-handed neutrino (Ni) mass spectrum obtained from the fit is strongly hierarchical, suggesting that B − L asymmetry is dominantly produced from N2 dynamics while N1 is responsible for erasing the excess asymmetry. With this rather constrained Yukawa sector, fits are obtained both for normal and inverted ordered neutrino mass spectra, consistent with leptonic CP-violating phase δCP indicated by global fits of neutrino oscillation data, while also satisfying the current limits from neutrinoless double beta decay experiments. In particular, the leptonic CP-violating phase has a preference to be in the range δCP ≃ (230 – 300)°. We also show the consistency of the framework with gauge coupling unification and proton lifetime limits.
Eikonal amplitudes on the celestial sphere
Authors: Adamo Tim , Bu Wei , Tourkine Piotr , Zhu Bin 
Published: October 2024

Abstract
Celestial scattering amplitudes for massless particles are Mellin transforms of momentum-space scattering amplitudes with respect to the energies of the external particles, and behave as conformal correlators on the celestial sphere. However, there are few explicit cases of well-defined celestial amplitudes, particularly for gravitational theories: the mixing between low- and high-energy scales induced by the Mellin transform generically yields divergent integrals. In this paper, we argue that the most natural object to consider is the gravitational amplitude dressed by an oscillating phase arising from semi-classical effects known as eikonal exponentiation. This leads to gravitational celestial amplitudes which are analytic, apart from a set of poles at integer negative conformal dimensions, whose degree and residues we characterize. We also study the large conformal dimension limits, and provide an asymptotic series representation for these celestial eikonal amplitudes. Our investigation covers two different frameworks, related by eikonal exponentiation: 2 → 2 scattering of scalars in flat spacetime and 1 → 1 scattering of a probe scalar particle in a curved, stationary spacetime. These provide data which any putative celestial dual for Minkowski, shockwave or black hole spacetimes must reproduce. We also derive dispersion and monodromy relations for these celestial amplitudes and discuss Carrollian eikonal-probe amplitudes in curved spacetimes.
Facial and dental arch shape in individuals with different bite force levels
Authors: Nocera Quezada Ana , Muñoz María Jesús , Schulz-Kornas Ellen , Bemmann Maximilian , Kupczik Kornelius , Schierz Oliver , Toro-Ibacache Viviana 
Published: October 2024

Abstract
Purpose
This pilot study aimed to assess the relationship between bite force variation and dental arch and facial shape using geometric morphometrics, an advanced method of statistical analysis that provides a detailed shape analysis of a structure considering the spatial relationship of its parts.

Methods
The sample consisted of 16 German adult men and women. For each individual, maximum bite force was recorded in four positions: maximum intercuspation, protrusion, laterotrusion to the right and to the left. Facial and three-dimensional (3D) dental reconstructions were obtained from 3D facial photographs and 3D scans of dental stone models. A total of 51 landmarks were placed. General shape variation was assessed by principal component analysis. Partial least squares analyses were performed to evaluate the covariation between bite force, facial shape, and dental shape.

Results
There was no clear pattern or statistically significant covariation between our variables.

Conclusions
Our results suggest a weak relationship between bite force, dental arch, and facial shape. Considering previous work in this field, we propose that low masticatory loads, characteristic in Western urban populations, may explain this. Further studies should, therefore, address this issue, taking into account effect size, the mechanical properties of the diet, and other relevant variables.