bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH TINGKAT SUKU BUNGA, BOND RATING, UKURAN PERUSAHAAN, DEBT TO EQUITY RATIO (DER) TERHADAP YIELD TO MATURITY OBLIGASI KORPORASI DI BEI PERIODE TAHUN 2010-2012.
Authors: , Hendaryadi , Yusniar Meina Wulansari , Hadi Abdul 
Published: July 2019

<p><em>This study aimed to analyze the effects of interest rates, bond rating, company size, and debt to equity ratio (DER) of the yield to maturity (YTM) of corporate bonds in Indonesia Stock Exchange. Previous researches showed different results, therefore, it is necessary to re- study by testing the four variables on the yield to maturity.</em></p><p><em>The population in this study was all corporate bonds listed and traded on the Stock Exchange in the period of 2010-2012. There were 324 bonds. Based on the Purposive sampling criteria, 66 bonds were obtained. The research hypothesis was tested by multiple linear regression (multiple regression) and the analysis tools were company's financial statements, market price of the bond, SBI interest rate and bond ratings.</em></p><p><em>The results showed that the variable interest rates and the debt to equity ratio did not significantly affect the yield to maturity of the bonds. Variable bond rating and company size gave significant</em><em> </em><em>n</em><em>e</em><em>g</em><em>a</em><em>ti</em><em>ve</em><em> </em><em>ef</em><em>f</em><em>ec</em><em>t</em><em>s</em><em> </em><em>ontheyield</em><em> </em><em>t</em><em>omaturity</em><em> </em><em>of</em><em> </em><em>t</em><em>he</em><em> </em><em>bonds.</em><em></em></p>
PENGARUH KUALITAS PRODUK, INOVASI PRODUK DAN PROMOSI TERHADAP KEPUTUSAN PEMBELIAN PRODUK HI JACK SANDALS BANDUNG
Authors: Ernawati Diah 
Published: July 2019

<p><em>This study aims to determine and analyze the influence of product quality, product innovation and promotion to product purchase decision of "Hi Jack Sandals Bandung". Data were collected by questionnaire distribution technique using Likert scale. The population in this study was obtained from the transaction data "Hi Jack Sandals Bandung" in January-July 2017 amounted to 3,033 transactions.The sample wasselected using purposive sampling obtained100 respondents. Hypothesis testing in this study usingclassical assumption test, multiple linear regression with α 0,05, whichdetermine, fit test model (F test), and t test with SPSS Program version 24. The results of this study indicate that variables of product qualityand promotion have significant positive effectson purchase decision,while variable of product innovation has no significant effect on purchase decision. </em></p>
PENGARUH MOTIVASI, PENDIDIKAN, PELATIHAN DAN PENGALAMAN KERJA TERHADAP KINERJA GURU SMKN 5 BANJARMASIN
Authors: Harlina Yuse , Bachri Ahmad Alim 
Published: July 2019

<p><em>This research aims to find out and analyze the influence of motivation (X1), Education (X2), Training (X3) Work Experience (X4) as independent variables either partially or simultaneously to the Teacher Performance (Y) as the dependent variable in SMKN 5 Banjarmasin.</em></p><p><em> This research method using purposive sampling technique with sample of 96 teachers SMKN 5 Banjarmasin. Variable measurement technique Likert scale with a weight scale from 1 to 5. To determine the correlation between the variables X1, X2, X3, and X4 towards Y, multiple linear regression correlation technique was used; and to test the significance level, the form of test deteminasi coefficient test was used ;and F test and t test used using SPSS 16 series.</em></p><p><em>The research concludes that there is a significant positive effect of each variable indenvenden variables simultaneouslyand partially towards the dependent variables. Among the four highest indenvenden variables, the variable Work experience (X4) was the highest variable compared to the independent variables towards teacher performance in SMKN 5 Banjarmasin</em></p>
Desain Interaksi Aplikasi Diskusi-Belajar Mengadopsi Media Sosial Memanfaatkan Prinsip Desain Nielsen
Authors: Persada Andhika Giri 
Published: July 2019

E-Learning has been used as one of media that is used in the online-based learning process. Regarding to the fact about social media utilization by students, ideas are generated by adopting interactions from social media. Social media had proven able to attract various users, such as students. Utilization of mobile-based device, improve student's interest to use social media. Based on those facts, this study aims to design the interaction which is adopted from social media, named Diskusi-Belajar. There are two fundamental behind the reasons choosing social media as subject. First, social media had been proven able to attract users to communicate each other interactively. Second, social media has intuitive flow of interaction and interface which making it easier to be used. In this study, elements of the social media were converted into interaction design of Diskusi-Belajar. Interaction design is produced on mobile-based platform. In order to ensure usability quality, ten principles of the Nielsen's design are used as a guideline. Five evaluators are involved to measure interaction design and generated three times iterations. Conclusions of the study is, although not all Nielsen's design principles are accommodated, the elements which are generated from previous studies have succesfully implemented in Diskusi-Belajar and produce good usability.
EFFECT OF PERSONALITY, ORGANIZATIONAL CLIMATE, AND WORK SATISFACTION ON ORGANIZATIONAL CITIZENSHIP BEHAVIOR TEACHER IN SECONDARY HIGH SCHOOL IN THE CITY OF ADMINISTRATION JAKARTA CENTER PROVINCE DKI JAKARTA
Authors: Asri Asri 
Published: July 2019

The purpose of this research is to study the influence of personality, organizational climate, and job satisfaction toward the Organizational Citizenship Behavior of teachers at public vocational high school in Central Jakarta Administration city of DKI Jakarta province. This research uses quantitative approach with survey method. The population of this research is all civil servant teachers at 14 public vocational high schools in Central Jakarta Administration. The number of samples of the study were 212 teachers who were taken with the Slovin formula of a population of 451 teachers. Data collection of research with questionnaires then analyzed descriptive statistics and inferential statistical path analysis. Based on hypothesis testing, 1) there is positive direct effect of personality toward Organizational Citizenship Behavior, 2) there is positive direct effect of organizational culture toward Organizational Citizenship Behavior; 3) there is positive direct effect of job satisfaction toward Organizational Citizenship Behavior; 4) there is positive direct influence Personality to Job Satisfaction, and 5) there is a direct positive influence of organizational climate on Job Satisfaction. Thus to improve OCB teachers in vocational high schools by improving teacher personality, quality organizational climate, increasing teacher job satisfaction.
Keywords: Organizational Citizenship Behavior, Personality, Organizational Climate and job saticfication
THE EFFECT OF PERSONALITY, WORK STRESS AND DECISION MAKING TO ORGANIZATIONAL COMMITMENT AT LIMITED COMPANY OF BHUMYAMCA SEKAWAN IN SOUTH JAKARTA
Authors: SARIWULAN TUTY 
Published: July 2019

This title of this research is the influence of employees personality, work stress dan decision making to organizational commitment at Limited Company of Bhumyamca Sekawan in South Jakarta.This study used quantitative approach with survey methods and path analysis technique. The amount of population is 213 employees and using random sampling technique, so the total of sample is 70 employees calculated by slovin formulation Data that used in this research is quantitative data with path analysis methods to find out the path coefficient score. Based on the calculation and hypothesis test, can be concluded as these results: (1) personality has direct positive influence to decision making; (2) work stress has direct positive influence to decision making; (3) personality has direct positive influence to organizational commitment; (4) work stress has direct positive influence to organizational commitment; (5) decision making has direct positive influence to organizational commitment.
Keywords: personality, work stress, decision making and organizational commitment
School-based nutrition interventions for Indigenous children in Canada: A scoping review
Authors: Gillies Christina , Blanchet Rosanne , Gokiert Rebecca , Farmer Anna , Thorlakson Jessica , Hamonic Laura , Willows Noreen D. 
Published: July 2019

Abstract
Background

Indigenous children in Canada (First Nations, Inuit, and Métis) are disproportionally affected by nutrition-related chronic diseases such as obesity and diabetes. Comprehensive school-based nutrition interventions offer a promising strategy for improving children’s access to healthy foods and sustaining positive eating behaviors. However, little is known about school-based nutrition interventions for Indigenous children. The objectives of this scoping review were to identify school-based nutrition interventions for Indigenous children in Canada and describe their components.

Methods

The scoping review consisted of searches in seven peer-reviewed databases and a general web search for grey literature. Eligibility criteria were applied by two reviewers, and data were extracted and charted by one reviewer using components of comprehensive school health (social and physical environment, teaching and learning, policy, partnerships and services) and additional components with relevance to Indigenous interventions (cultural content, Indigenous control and ownership, funding source, evaluation). Thematic analysis provided a description of interventions.

Results

Sixty-five sources of evidence, representing 34 unique interventions met the inclusion criteria. The majority (97%) of interventions targeted the social and physical environment, most often by offering food programs. Over half of interventions also incorporated teaching and learning (56%) and partnerships and services (59%), but fewer included a policy component (38%). Many interventions included a cultural component (56%) and most (62%) were owned and controlled by Indigenous communities. Finally, over half of interventions disclosed their source(s) of funding (59%), but less than half (41%) included an evaluation component.

Conclusions

The review suggests that school-based interventions for Indigenous children can be more comprehensive by incorporating culturally-relevant nutrition education and professional development opportunities for teachers, written school nutrition policies, and activities that actively engage families and community members. The continued focus on Indigenous control and ownership and incorporation of content specific to individual communities may enhance cultural relevancy and sustainability of interventions. Furthermore, there is a need to increase intervention evaluation and the sharing of resources related to funding. These recommendations may be used by communities, as well as by researchers and professionals working with communities, in developing comprehensive school-based nutrition interventions to improve the eating behaviors of Indigenous children.
A Critical Evaluation of Decentralised Radiological Services in Norway – a rural case study
Authors: Myklebust Aud Mette , Eide Hilde , Ellis Brian , Beattie Rona 
Published: July 2019

Abstract
Background

Implementation of the Norwegian government’s Coordination Reform (2012) aims to decentralise health care services from centralised hospitals to the local communities. Radiological services in Norway are mainly organised in hospitals, because of the significant financial and human resource demands engendered by the need for advanced technological equipment, and specialised staff. Some selected conventional x-ray services have been decentralised into rural communities. The purpose of this case study was to evaluate different stakeholders’ perceptions of organizing decentralised radiological services in a rural area in Norway.

Methods

Following an extensive policy and literature review and a survey of GPs in the rural area being investigated two focus groups were conducted to obtain stakeholder’s evaluation of the radiological services in both hospital and rural contexts. The key emergent themes from the literature - decentralization, quality, professional roles, organisation and economic consequences – were discussed with each focus group. Thematic analysis was used for analyzing the primary data collected.

Results

Four main themes emerged from the focus groups: organisation, quality, funding of radiological services and cooperation between health care professions and health care levels. The quality of service was found to be inadequate in some areas because of the superficial level of training given to non-radiographic staff. It was found that the organisation of decentralised radiological services to rural areas is challenging because of the way health services are structured in Norway. This structural framework increases the need for effective cooperation and responsibility between health care professions and levels. There needs to be improved co-working by clearly defining roles and responsibilities.

Conclusions

The stakeholders agreed that decentralized radiological services is important. Quality of the service could be improved and should be given priority. A key recommendation for the organisation of rural radiological service was the development of a satellite link with an acute hospital. Structural change to the financial system whereby money follows patients, might also facilitate more patient-centred services across healthcare levels. Improved mutual understanding between rural radiolog­ical services and hospital specialists and managers is important for a high quality and consistent radiological service to be delivered across Norway.
Sphk1 involves in the regulation of autophagy process in cardiac myocyte cells at high glucose condition
Authors: Ai Wen , Xie Peiyi , Ling Li , Gao Yulan , Wang Lei , Fang Hongcheng , Chen Yanwei 
Published: July 2019

Abstract
Diabetic cardiomyopathy is the myocardium disorders caused by diabetes mellitus, which has become a key concern bringing heavy burden to the public health. Autophagy is one of activities involving in the pathogenesis of diabetic cardiomyopathy. Sphk1 gene plays a crucial role in cell survival and growth, and regulation of many diseases including diabetes and cardiovascular disease. However, the pathogenesis of diabetic cardiomyopathy remains poorly understood. To this aim, the study established adenovirus vectors expressing Sphk1 and shSphk1 to investigate the effects of Sphk1 on autophagy and cell survival in myocardial cells under high glucose conditions (25 mM). It was found that overexpression of Sphk1 promoted autophagy activity in H9c2 cells under high glucose treatment measured by various methodologies including qRT-PCR, western blot, fluorescence microscope, and so on. Inhibition of autophagy decreased cell vitality under high glucose condition. A broadly used medicine silibinin was demonstrated to induce autophagy in a dose-dependent manner. Herein, the findings in the present study may provide useful reference for unveiling the pathogenesis of diabetic cardiomyopathy and developing novel therapies treating diabetic cardiomyopathy.
Patency of conduits in patients who received internal mammary artery, radial artery and saphenous vein graft
Authors: Royse Alistair , Pamment William , Pawanis Zulfayandi , Clarke-Errey Sandy , Eccleston David , Ajani Andrew , Wilson William , Canty David , Royse Colin 
Published: July 2019

Abstract
Background
Where each patient has all three conduits of internal mammary artery (IMA), saphenous vein graft (SVG) and radial artery (RA), most confounders affecting comparison between conduits can be mitigated. Additionally, since SVG progressively fails over time, restricting patient angiography to the late period only can mitigate against early SVG patency that may have occluded in the late period. An angiographically normal lumen in a patent graft, in the late period, would predict ongoing patency thereafter; whereas an irregular lumen would predict progression of conduit atheroma and possible failure in the long term.

Objectives
The primary analysis was perfect patency and secondary analysis was overall patency including angiographic evidence of conduit lumen irregularity from conduit atheroma.

Methods
Research protocol driven conventional angiography was performed for patients with at least one of each conduit of IMA, RA and SVG and a minimum of 7 years postoperative. Generalized linear mixed model (GLMM) was used. Patency excluded occluded or “string sign” conduits. Perfect patency was present in patent grafts if there was no lumen irregularity.

Results
50 patients underwent coronary angiography at overall duration postoperative 13.1±2.9, and age 74.3±7.0 years. Of 196 anastomoses, IMA 62, RA 77 and SVG 57. Most IMA were to the left anterior descending territory and most RA and SVG were to the circumflex and right coronary territories. Perfect patency RA 92.2% was not different to IMA 96.8%, P=0.265; and both were significantly better than SVG 17.5%, P<0.001. Patency RA 93.5% was also not different to IMA 96.8%, P=0.146, and both arterial conduits were significantly higher than SVG 82.5%, P=0.029. Grafting according to coronary territory was not significant for perfect patency, P=0.961 and patency 0.201. Coronary stenosis predicted perfect patency for RA only, P=0.030 and for patency, RA, P=0.007, and SVG, P=0.032.

When both arterial conduits were combined, perfect patency, P<0.001, and patency, P=0.017, were superior to SVG.

Conclusions
All but one patent internal mammary artery or radial artery grafts had perfect patency and had superior perfect patency and overall patency compared to saphenous vein grafts.
Late Diagnosis among patients with Prostate Cancer at the Uganda Cancer Institute: A retrospective cohort study
Authors: Bunani Nelson , Kisakye Angela Nakanwagi , Ssennyonjo Aloysius , Nuwaha Fred 
Published: July 2019

Abstract
Background

Late diagnosis of prostate cancer is common in Uganda and elsewhere. Diagnosis in advanced stages is associated with high mortality, morbidity and low quality of life. We estimated time taken from perception of symptoms attributable to prostate cancer to biopsy among patients with prostate cancer at the Uganda Cancer Institute (UCI) and the associated factors.

Methods

We conducted a retrospective cohort analysis of records of 280 patients with histologically confirmed diagnosis of prostate cancer at UCI from January 2016 to December 2017. Time to diagnosis was obtained from the difference between the approximate date of onset of initial symptoms and date when a biopsy was taken. Late diagnosis was that when an individual was diagnosed with prostate cancer stage III or IV whereas stages I and II were classified as early. We used modified poisson regression to assess factors associated with timing of diagnosis among patients.

Results

The median time from first perceived symptoms to biopsy for prostate cancer patients was 12 (IQR5-24) months and 76% were diagnosed after 4 months of symptoms. Median age at time of diagnosis of patients was 70 (IQR66-74.5) years and at least 50% were aged between 65-74 years. About 81.8% of the patients were diagnosed late; of which 35.7% were in stage III and 46.1% were in stage IV. Nearly all patients presented with raised prostate specific antigen with median prostate specific antigen of 100.2 (IQR36.02-350) ng/ml of blood at the time of admission. In adjusted analysis, a patients whose biopsies were taken before 5 months of recognising symptoms were two times as likely to have cancer stage I and II compared to those patients in whom the biopsies were taken after 4 months.

Conclusion

More than three in four patients were diagnosed late. Taking a biopsy after 4 months of initiation of symptoms was partially responsible for the delay. To improve time to diagnosis, communities should be educated about symptoms of prostate cancer and advised to seek health care early. Health care workers should be sensitised to suspect prostate cancer among patients to allow timely referral for appropriate specialised assessment and management.
Targeting Toll-like receptor 4 with CLI-095 (TAK-242) enhances the antimetastatic effect of the estrogen receptor antagonist fulvestrant on non-small cell lung cancer
Authors: fan Sheng , Qiu Wenlin , Li Lequn , Li Dong , Liao Yongde , Cao Xiaonian , Ai Bo 
Published: July 2019

Abstract
Background

Estrogen plays a critical role in the invasiveness and metastasis of non-small cell lung cancer (NSCLC) through estrogen receptor β (ERβ). However, the antimetastatic effect of the ERβ antagonist fulvestrant was still limited in NSCLC patients in phase II clinical trials. Recently, Toll-like receptor 4 (TLR4) signaling was implicated in NSCLC metastasis. Our present study aimed to evaluate the synergistic antimetastatic effect of a combination of fulvestrant and the TLR4-specific inhibitor CLI-095 (TAK-242) on human NSCLC cells.

Methods

The expression levels of ERβ and TLR4 were detected by immunohistochemical (IHC) analysis of 180 primary NSCLC and 30 corresponding metastatic lymph node samples. The association between ERβ and TLR4 expression was analyzed. The aggressiveness of NSCLC cells treated with fulvestrant, CLI-095 or the drug combination and formation status of their invadopodia, invasion-associated structures, were investigated. The protein levels in NSCLC cells in different groups were determined by Western blot and immunofluorescence analyses.

Results

Here, a positive correlation between ERβ and TLR4 expression was observed in both primary NSCLC tissue (Spearman’s Rho correlation coefficient = 0.411, p<0.001) and metastatic lymph node tissue (Spearman’s Rho correlation coefficient = 0.374, p=0.009). The protein levels of ERβ in the A549 and H1793 cell lines induced by estrogen were decreased by fulvestrant, and this suppressive effect was significantly enhanced when fulvestrant was combined with CLI-095 (p<0.05 for both treatments). Both the migration and invasion of NSCLC cells were suppressed by fulvestrant or CLI-095 alone, and the combination of fulvestrant+CLI-095 showed the strongest inhibitory effect (p<0.05 for all treatments). In addition, the results demonstrated that CLI-095 also helped fulvestrant restrict the formation and function of invadopodia in NSCLC cells (p<0.05).

Conclusions

Collectively, our study results suggested that CLI-095 enhances the antimetastatic effect of fulvestrant on NSCLC and provided support for further investigation of the antitumor activity of combined therapy with antiestrogen and anti-TLR4 agents in the clinic.