bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing the serum TAG response to high-dose supplementation of either DHA or EPA among individuals with increased cardiovascular risk: the ComparED study
Authors: Allaire Janie , Vors Cécile , Harris William S. , Jackson Kristina Harris , Tchernof André , Couture Patrick , Lamarche Benoît 
Published: March 2019

AbstractStudies have shown that the reduction in serum TAG concentrations with long-chain n-3 fatty acid supplementation is highly variable among individuals. The objectives of the present study were to compare the proportions of individuals whose TAG concentrations lowered after high-dose DHA and EPA, and to identify the predictors of response to both modalities. In a double-blind, controlled, crossover study, 154 men and women were randomised to three supplemented phases of 10 weeks each: (1) 2·7 g/d of DHA, (2) 2·7 g/d of EPA and (3) 3 g/d of maize oil, separated by 9-week washouts. As secondary analyses, the mean intra-individual variation in TAG was calculated using the standard deviation from the mean of four off-treatment samples. The response remained within the intra-individual variation (±0·25 mmol/l) in 47 and 57 % of participants after DHA and EPA, respectively. Although there was a greater proportion of participants with a reduction &gt;0·25 mmol/l after DHA than after EPA (45 υ. 32 %; P &lt; 0·001), the mean TAG reduction was comparable between groups (–0·59 (sem 0·04) υ. –0·57 (sem 0·05) mmol/l). Participants with a reduction &gt;0·25 mmol/l after both DHA and EPA had higher non-HDL-cholesterol, TAG and insulin concentrations compared with other responders at baseline (all P &lt; 0·05). In conclusion, supplementation with 2·7 g/d DHA or EPA had no meaningful effect on TAG concentrations in a large proportion of individuals with normal mean TAG concentrations at baseline. Although DHA lowered TAG in a greater proportion of individuals compared with EPA, the magnitude of TAG lowering among them was similar.
Late Eocene – Early Miocene facies and stratigraphic development, Taranaki Basin, New Zealand: the transition to plate boundary tectonics during regional transgression
Authors: Strogen Dominic P. , Higgs Karen E. , Griffin Angela G. , Morgans Hugh E. G. 
Published: March 2019

AbstractEight latest Eocene to earliest Miocene stratigraphic surfaces have been identified in petroleum well data from the Taranaki Basin, New Zealand. These surfaces define seven regional sedimentary packages, of variable thickness and lithofacies, forming a mixed siliciclastic–carbonate system. The evolving tectonic setting, particularly the initial development of the Australian–Pacific convergent margin, controlled geographic, stratigraphic and facies variability. This tectonic signal overprinted a regional transgressive trend that culminated in latest Oligocene times. The earliest influence of active compressional tectonics is reflected in the preservation of latest Eocene – Early Oligocene deepwater sediments in the northern Taranaki Basin. Thickness patterns for all mid Oligocene units onwards show a shift in sedimentation to the eastern Taranaki Basin, controlled by reverse movement on the Taranaki Fault System. This resulted in the deposition of a thick sedimentary wedge, initially of coarse clastic sediments, later carbonate dominated, in the foredeep close to the fault. In contrast, Oligocene active normal faulting in a small sub-basin in the south may represent the most northerly evidence for rifting in southern Zealandia, related to Emerald Basin formation. The Early Miocene period saw a return to clastic-dominated deposition, the onset of regional regression and the southward propagation of compressional tectonics.
CLAUDIUS’ HOUSEBOAT
Authors: Roncaglia Carolynn 
Published: March 2019

In the first months of 44 ce, the Roman emperor Claudius, after spending as few as sixteen days in Britain, returned to Rome to celebrate his triumph. On his journey back to Rome, he stopped near the mouth of the Po river to take a cruise, as Pliny the Elder describes:
The Po is carried to Ravenna by the Canal of Augustus; this part of the river is called the Padusa, formerly called the Messanicus. Nearby it forms the large harbour Vatrenus; from here Claudius Caesar, when celebrating his triumph over Britain, sailed out into the Adriatic, in what was more a domus than a ship.
Pliny describes a vessel that was less a boat than a floating domus, a somewhat ambiguous word which denotes a structure ranging in size from a modest house to a palace. The cruise, like his time in Britain, was short, and yet this cruise was a part of meticulously planned campaign, a campaign not just for conquest but also for Claudius’ reputation. Aulus Plautius, the experienced commander and suffect consul of 29 ce, had been sent ahead with the army, and Claudius’ freedman Narcissus was also on hand to oversee the invasion. The Roman army achieved initial successes and then halted until the emperor could arrive to command the final assault on the stronghold at Camulodunum (Colchester). While Claudius only spent around two weeks in Britain, his journey to and from the island took six months. Claudius travelled to Britain with a huge entourage, including senators, relatives, and even elephants. This was a mammoth undertaking, and one that seems to have very carefully planned, to ensure military success and a positive reputation for a new emperor of still uncertain legitimacy.
Bridging the Gap: Lottery-Based Procedures in Early Parliamentarization
Authors: Cirone Alexandra , Van Coppenolle Brenda 
Published: March 2019

AbstractHow is the use of political lotteries related to party development? This article discusses the effects of a lottery-based procedure used to distribute committee appointments that was once common across legislatures in nineteenth-century Europe. The authors analyze the effects of a political lottery in budget committee selection in the French Third Republic using a microlevel data set of French deputies from 1877 to 1914. They argue that the adoption and benefit of lottery-based procedures were to prevent the capture of early institutions by party factions or groups of self-interested political elites. The authors find that partial randomization of selection resulted in the appointment of young, skilled, middle-class deputies at the expense of influential elites. When parties gained control of committee assignments in 1910, selection once again favored elites and loyal party members. The authors link lottery-based procedures to party development by showing that cohesive parties were behind the institutional reform that ultimately dismantled this selection process. Lottery-based procedures thus played a sanitizing role during the transformation of emerging parliamentary groups into unified, cohesive political parties.
Topos points of quasi-coherent sheaves over monoid schemes
Authors: PIRASHVILI ILIA 
Published: March 2019

AbstractLet X be a monoid scheme. We will show that the stalk at any point of X defines a point of the topos of quasi-coherent sheaves over X. As it turns out, every topos point of is of this form if X satisfies some finiteness conditions. In particular, it suffices for M/M× to be finitely generated when X is affine, where M× is the group of invertible elements.This allows us to prove that two quasi-projective monoid schemes X and Y are isomorphic if and only if and are equivalent.The finiteness conditions are essential, as one can already conclude by the work of A. Connes and C. Consani [3]. We will study the topos points of free commutative monoids and show that already for ℕ∞, there are ‘hidden’ points. That is to say, there are topos points which are not coming from prime ideals. This observation reveals that there might be a more interesting ‘geometry of monoids’.
Evaluating the Acceptability and Validity of Assessing Pain and Posttraumatic Stress Symptoms in an Adaptable eHealth System for School-Age Children
Authors: Kassam-Adams Nancy , Kohser Kristen L. , McLaughlin Jeffery , Winston Flaura , Marsac Meghan L. 
Published: March 2019

Objective: The objective of this study is to provide initial evaluation of the acceptability of a new eHealth system incorporating personalized self-report assessment of multiple health domains in school-age children and assess convergent validity of two brief measures presented via this system. Methods: Ill or injured children ( N = 167) ages 6–14 recruited in two pediatric health care systems used the prototype eScreen interface on a mobile device to select an avatar and complete brief assessments of pain and posttraumatic stress symptoms (PTSS). Children rated technology acceptability and completed validated measures for pain and PTSS. Results: Children’s ratings indicated they found the eScreen interface easy to use (mean rating 4.4 on a 1–5 scale), potentially useful in helping them recover ( M = 3.7), and would use/recommend it ( M = 4.0). Among children ages 6–8, mean ratings were as follows: easy to use (3.7), usefulness (3.3), and would use/recommend (3.4). Acceptability was largely consistent across child gender, family income, or usual access to mobile devices. eScreen measures showed strong convergent validity with established measures. The eScreen Pain Screener was highly correlated ( r = .86–.92) and evidenced strong agreement with two validated pain measures. eScreen PTSS scores were strongly correlated with a validated PTSS measure ( r = .67); a positive PTSS screen was associated with significantly higher PTSS severity. Conclusions: Study results support the acceptability (ease of use, intention to use/recommend, perceived usefulness) of these tools for older school-age children and provide strong initial evidence for the validity of two brief measures presented in a novel digital modality. Implications for Impact Statement Key parts of an adaptable eHealth screening system were rated positively by children ages 9–14; younger children’s ratings suggest the need for additional development for their use. Results support the validity of brief pain and posttraumatic stress measures presented via this system and personalized with an avatar chosen by the child.
Iterative Development of a Web-Based Intervention for Families of Young Children With Type 1 Diabetes: DIPPer Academy
Authors: Marker Arwen M. , Monzon Alexandra D. , Goggin Kathy J. , Clements Mark A. , Patton Susana R. 
Published: March 2019

Objective: A new diagnosis of type 1 diabetes mellitus (T1D) can be stressful for families as they are expected to learn a large amount of information regarding disease management and treatment in a short period of time. Currently, parents complete diabetes education at the time of diagnosis. However, this format may not be sustainable as rates of T1D climb. The current study aimed to develop an online platform to provide educational material in the form of video microlectures using an iterative, user-centered design process. Methods: In the first stage of development, parents of young children with T1D identified information they felt was most important to their child’s T1D care. In the second stage, health care providers contributed qualitative and quantitative feedback regarding the educational material and video mock-ups. The third stage involved parents of young children with T1D providing feedback on the completed video microlectures. Results: Providers and parents reported that the videos were highly useful, important to T1D care, and the majority would recommend them to other parents. Conclusions: The iterative design process used by the research team incorporated multiple perspectives and ultimately developed educational resources that were well-received by providers, researchers, and parents. Implications for Impact Statement This study used an iterative, user-centered design to develop a series of web-based videos for parents of young children with type 1 diabetes. Primary stakeholders, both health care providers and parents, described videos as highly important, useful, enjoyable, and would recommend these resources to others. Parents rated videos highly across a variety of presentations that ranged in development time and cost, indicating that researchers can feasibly and cost-effectively create web-based resources for parents.
Feasibility, Acceptability, and Preliminary Effectiveness of an Adaptive Text Messaging Intervention for Adolescent Weight Control in Primary Care
Authors: Jensen Chad D. , Duraccio Kara M. , Barnett Kimberly A. , Fortuna Christopher , Woolford Susan J. , Giraud-Carrier Christophe G. 
Published: March 2019

Objective: Behavioral interventions for adolescent weight control are often difficult to access because they are rarely provided in primary health care. This study was designed to assess the feasibility, acceptability, and preliminary effectiveness of a motivational interviewing plus adaptive text messaging intervention for adolescent weight control delivered in primary care. Methods: Forty-seven overweight adolescents (aged 13–18 years) participated in a single, hour-long, in-person motivational interviewing session in their primary care pediatrician’s office with a clinical psychology doctoral student. All participants monitored diet, physical activity, and weight over 6 months and reported this information nightly via text message. Participants were selected randomly to receive computer-tailored adaptive text messages 3 times per day at mealtimes as an additional intervention component. Results: Participants found the intervention to be acceptable and beneficial for promoting weight-related behavior change. Adherence to self-monitoring was significantly higher in the adaptive text messaging group. Although body mass index z-score (zBMI) change was not significantly different across treatment groups, participants receiving the adaptive text message intervention demonstrated a reduction of .32 zBMI standard deviation units from before to after intervention, t(28) = −2.84, p < .01, d = .54, whereas zBMI did not change for individuals receiving the control intervention. Several domains of weight-related quality of life improved during the intervention period irrespective of treatment assignment. Conclusions: Study findings suggest that a behavioral weight control intervention delivered in a primary care is acceptable/feasible and may produce reductions in zBMI. Fully powered studies to further evaluate this intervention approach are warranted. Implications for Impact Statement This pilot trial demonstrates that adaptive text messaging is a feasible, acceptable method for delivering weight control intervention content as an addition to in-person treatment for overweight adolescents. Furthermore, our findings suggest that interventions including adaptive text messages may improve self-monitoring adherence and produce superior weight loss outcomes.
Privacy Perceptions and Norms in Youth and Adults
Authors: Bietz Matthew J. , Cheung Cynthia , Rubanovich Caryn Kseniya , Schairer Cynthia , Bloss Cinnamon S. 
Published: March 2019

Objective: This exploratory study examines privacy perceptions and preferences among adolescent and young adult (AYA) and adult individuals with an emphasis on health-related information. Method: Participants ( N = 112) completed surveys including measures of privacy concern, consumer control of information, online privacy concern and behavior, and sensitivity of personal information. Results: AYAs ( n = 36) and adults ( n = 76) showed similar levels of general privacy concern; specifically, their ratings of the sensitivity of non-health-related personal data did not differ. AYAs’ ratings of various health information sensitivities were lower than adults’ ratings, and AYAs reported less concern on subscales addressing online and consumer data collection. Conclusion: Discrepancies between AYA and adult responses to different privacy scales suggest contextual integrity at work. That is, AYAs’ and adults’ privacy perceptions differ based on the type of information being shared, and they draw on different norms to govern information flow. AYAs are more likely to feel they have control over their personal information and feel comfortable employing privacy protecting strategies. AYAs are less likely to see online information collection as a violation of an implied social contract. This study highlights differences in AYA and adult attitudes toward privacy and suggests that AYAs care about privacy but perceive certain types of information collection as less threatening than adults. Implications for Impact Statement Adolescents and young adults (AYAs) and adults follow different norms with regards to appropriate information flow. Policymakers, parents, educators, and others who are charged with protecting young people should be aware that AYAs may be more open to information flows that they perceive as appropriate, including health information flows. Healthcare providers who encourage AYAs to use mobile health apps and devices should be mindful of privacy concerns as they work to serve their patients’ best interests.
ADP-Ribose and oxidative stress activate TRPM8 channel in prostate cancer and kidney cells
Authors: Baş Ercan , Nazıroğlu Mustafa , Pecze László 
Published: March 2019

AbstractActivation of TRPM8 channel through oxidative stress may induce Ca2+ and pro-apoptotic signals in prostate cancer and kidney cells. The aim of this study was to evaluate activation of TRPM8 can increase apoptosis and oxidative stress in the prostate cancer (Du145M8), TRPM8 knock out (Du 145M8KO), transfected (HEK293TM8) and non-transfected human kidney (HEK293) cells. Intracellular Ca2+ responses to TRPM8 activation were increased in the Du145M8 and HEK293TM8 cells from coming cumene hydrogen peroxide (CHPx), menthol, ADP-Ribose (ADPR), but not in the HEK293 and Du 145M8KO cells. The intracellular Ca2+ responses to both ADPR and CHPx were totally inhibited by the thiol cycle antioxidant glutathione, and TRPM8 blockers (N-(p-amylcinnamoyl)anthranilic acid and capsazepine). Apoptosis, Annexin V, mitochondrial membrane depolarization, intracellular ROS, caspase 3 and 9 values were increased through TRPM8 activation in the Du 145M8 but not in the Du 145M8KO and non-transfected HEK293 cells by CHPx and hydrogen peroxide. In conclusion, apoptotic and oxidant effects on the cells were increased activation of TRPM8 by oxidative stress and ADPR. Activation of TRPM8 through oxidative stress and ADPR in the cells could be used as an effective strategy in the treatment of prostate cancer cells.
Enabling Covert Body Area Network using Electro-Quasistatic Human Body Communication
Authors: Das Debayan , Maity Shovan , Chatterjee Baibhab , Sen Shreyas 
Published: March 2019

AbstractRadiative communication using electro-magnetic (EM) fields amongst the wearable and implantable devices act as the backbone for information exchange around a human body, thereby enabling prime applications in the fields of connected healthcare, electroceuticals, neuroscience, augmented and virtual reality. However, owing to such radiative nature of the traditional wireless communication, EM signals propagate in all directions, inadvertently allowing an eavesdropper to intercept the information. In this context, the human body, primarily due to its high water content, has emerged as a medium for low-loss transmission, termed human body communication (HBC), enabling energy-efficient means for wearable communication. However, conventional HBC implementations suffer from significant radiation which also compromises security. In this article, we present Electro-Quasistatic Human Body Communication (EQS-HBC), a method for localizing signals within the body using low-frequency carrier-less (broadband) transmission, thereby making it extremely difficult for a nearby eavesdropper to intercept critical private data, thus producing a covert communication channel, i.e. the human body. This work, for the first time, demonstrates and analyzes the improvement in private space enabled by EQS-HBC. Detailed experiments, supported by theoretical modeling and analysis, reveal that the quasi-static (QS) leakage due to the on-body EQS-HBC transmitter-human body interface is detectable up to <0.15 m, whereas the human body alone leaks only up to ~0.01 m, compared to >5 m detection range for on-body EM wireless communication, highlighting the underlying advantage of EQS-HBC to enable covert communication.
Five-month-old infants detect affiliation in colaughter
Authors: Vouloumanos Athena , Bryant Gregory A. 
Published: March 2019

AbstractColaughter–simultaneous laughter between two or more individuals–allows listeners across different cultures and languages to quickly evaluate affiliation within a social group. We examined whether infants are sensitive to acoustic information in colaughter that indicates affiliation, specifically whether they can differentiate colaughter between friends and colaughter between strangers. In the first experiment, infants who heard alternating trials of colaughter between friends and strangers listened longer to colaughter between friends. In the second experiment, we examined whether infants were sensitive to the social context that was appropriate for each type of colaughter. Infants heard colaughter between friends and colaughter between strangers preceded by a silent visual scene depicting one of two different social contexts: either two people affiliating or turning away from each other. Infants looked longer when the social scene was incongruent with the type of colaughter. By 5 months, infants preferentially listen to colaughter between friends and detect when colaughter does not match the valence of a social interaction. The ability to rapidly evaluate acoustic features in colaughter that reveal social relationships between novel individuals appears early in human infancy and might be the product of an adaptive affiliation detection system that uses vocal cues.
A continued fraction based approach for the Two-photon Quantum Rabi Model
Authors: Lupo Elena , Napoli Anna , Messina Antonino , Solano Enrique , Egusquiza Íñigo L. 
Published: March 2019

AbstractWe study the Two Photon Quantum Rabi Model by way of its spectral functions and survival probabilities. This approach allows numerical precision with large truncation numbers, and thus exploration of the spectral collapse. We provide independent checks and calibration of the numerical results by studying an exactly solvable case and comparing the essential qualitative structure of the spectral functions. We stress that the large time limit of the survival probability provides us with an indicator of spectral collapse, and propose a technique for the detection of this signal in the current and upcoming quantum simulations of the model.
Intraseasonal oscillation of deep currents influenced by mesoscale eddies in the Kuroshio Extension Region
Authors: Liu Yansong , Yu Fei , Nan Feng , Zhou Wenzheng 
Published: March 2019

AbstractIntraseasonal oscillation of deep currents in the Kuroshio Extension region is examined using observations from a collection of current meter moorings. The moored observations reveal variability with characteristic time scales of 23–38 days for velocity time series and of 38–99 days for temperature time series. The time series of normalized temperature (NT) in the deep ocean change correspondingly with sea level anomaly (SLA). The maximum correlation coefficient between NT in the deep ocean and SLA is also up to 0.7. Positive correlation is observed between deep currents and surface geostrophic current. Furthermore, the influence of mesoscale eddies on deep currents is examined by analyzing the data collected when cyclonic and anticyclonic eddies crossed the current meter mooring. Whether anticyclonic or cyclonic eddy intensified the deep currents from 2000 m to 4000 m in the same direction and increased the amplitude. These results provide observational evidence of intraseasonal oscillation in the deep ocean and the effect of mesoscale eddies on deep currents in the Kuroshio Extension region.