bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on robust fault-tolerant cooperative control for multi-stage satellites
Authors: Fan Mao , Li Jianping , Zhou Jianmin , Ren Bin , Chen Ao 
Published: November 2024

Abstract
The ultra-agile, ultra-stable, and ultra-pointing platform (ASP) is introduced on the basis of the satellite platform by using two-stage control to realize stable control and agile ability of the payload. In order to improve the reliability and attitude control capability of multi-stage satellites with a two-dimensional scanning motion mechanism, a robust fault-tolerant cooperative control algorithm for multi-stage satellites is proposed in this paper when the actuators of the ASP are faulty. Firstly, a dynamic model of a multi-stage satellite and typical fault models of actuators are established. The impact of faults on the multi-stage system is also analyzed in this paper. Secondly, a sliding mode fault observer is proposed for multi-stage satellites aiming at solving the problem of actuator failure. An adaptive sliding mode fault-tolerant control algorithm is designed, and the switch function is also improved which is chattering-free. The stability of the proposed controller is proved by using the Lyapunov stability principle. Finally, the effectiveness of the proposed control algorithm is verified through numerical simulations, and the comparison between four other fault-tolerant control algorithms demonstrates the superiority of the algorithm proposed in this paper.
Experimental and calculation investigation on perforated Liners’ acoustic impedance
Authors: Xu Jiaxin , Song Xiao , Gui Yifei 
Published: November 2024

Abstract
Acoustic impedance models are the most common method for representing the properties of engine nacelle liners. Although various models have been developed, it is difficult to validate the accuracy due to the limitation of impedance eduction techniques. For obtaining accurate impedance results, a series of perforated liners are manufactured and the impedance of all is measured by using both the microphone array method and in-situ method. The results of the test demonstrate that acoustic resistances are not sensitive to percent open areas, hole diameter, and the face sheet’s thickness, but the Mach number of the grazing flow in the duct can have a considerable effect on resistance. Furthermore, excellent agreement between predictions and measured data gives confidence that the Goodrich perforated liner impedance model is suitable for the design of engine nacelle liner.
Pregnancy, aortic events, and neonatal and maternal outcomes
Authors: Chen Shao-Wei , Chang Feng-Cheng , Chen Chun-Yu , Cheng Yu-Ting , Hsiao Fu-Chih , Tung Ying-Chang , Lin Chia-Pin , Wu Victor Chien-Chia , Chu Pao-Hsien , Chou An-Hsun 
Published: November 2024

Abstract

Background and Aims
This study aimed to evaluate the association between pregnancy and aortic complications and determine related maternal and neonatal outcomes.

Methods
Records of pregnancies and neonatal deliveries from the Taiwan National Health Insurance Research Database from 2000 to 2020 were retrieved. The incidence rate ratio (IRR) was calculated to evaluate the risk factors for aortic events. Survival analysis was conducted to compare maternal and neonatal mortality with and without aortic events.

Results
A total of 4 785 266 pregnancies were identified among 2 833 271 childbearing women, and 2 852 449 delivered neonates. In the vulnerable and control periods, 57 and 20 aortic events occurred, resulting in incidence rates of 1.19 and 0.42 aortic events per 100 000 pregnancies, respectively. Pregnancy was established as a risk factor for aortic events (IRR: 2.86, P &lt; .001). The 1-year maternal mortality rate was significantly higher in pregnancies with aortic events than in those without such events (19.3% vs. 0.05%, P &lt; .001). Neonates whose mothers experienced aortic events had a higher late mortality (6.3% vs. 0.6%, P &lt; .001).

Conclusions
The association between pregnancy and aortic events was established in this study. The results revealed that women are at risk of aortic events from the gestational period to 1-year postpartum. Maternal mortality was significantly higher in pregnancies with aortic events than in those without. A higher late mortality and more complications were noted for neonatal deliveries with maternal aortic events. Early awareness of pregnant women at risk of aortic events—especially those with concomitant hypertensive disorders of pregnancy, contributive family histories, or aortopathy—is crucial.
Good appellate practice means explaining decisions: how the overuse of one-word affirmances harms US patent law
Authors: Macedo Charles , Goldberg David , Hart Thomas , Dellaportas John , Zipper Jamie 
Published: November 2024

Abstract
The US Court of Appeals for the Federal Circuit issues one-word decisions under Local Rule 36 in roughly one-third of the patent appeals it hears. Although US law allows for one-word decisions, they should be rare because parties, reviewing courts and the public need transparency in decisions; explaining decisions promotes accuracy and quality in decision-making and helps prevent inconsistent legal outcomes. The Federal Circuit issues many more one-word affirmances than other US Courts of Appeals, which disparately affects patent law, and needs to be addressed to avoid increasing unclarity in the law.
Her Music Academia: A Public Scholarship Initiative
Authors: Bangura Lydia 
Published: November 2024

Abstract
As a subfield of music theory scholarship, public music theory engages audiences outside of the academy. The onset of the internet has additionally provided new open-access media and sites for music theoretical inquiry. Two ways in which public music theory exists on the internet are in the form of podcasting and blogging. In this essay, I explain the reasons I started my podcast and blog (both titled Her Music Academia), the ways the work has taken shape over the years, and what I have learned so far. Through these projects, I seek to introduce the process of becoming a music theorist to a public audience, highlight my own experience as a Black woman in academia, and create a sense of community around music theory. I continue the practice of learning in public by documenting the development of my research and ideas about music, and I encourage my audience to similarly embark on their own process of learning about music theory. Ultimately, Her Music Academia challenges academic music theorists to reevaluate its definition of scholarship and to consider how these two opposing methods of performing scholarship differ in goals and outcomes.
The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity
Authors: Cerezo Maria , Sollis Elliot , Ji Yue , Lewis Elizabeth , Abid Ala , Bircan Karatuğ Ozan , Hall Peggy , Hayhurst James , John Sajo , Mosaku Abayomi , Ramachandran Santhi , Foreman Amy , Ibrahim Arwa , McLaughlin James , Pendlington Zoë , Stefancsik Ray , Lambert Samuel A , McMahon Aoife , Morales Joannella , Keane Thomas , Inouye Michael , Parkinson Helen , Harris Laura W 
Published: November 2024

Abstract
The NHGRI-EBI GWAS Catalog serves as a vital resource for the genetic research community, providing access to the most comprehensive database of human GWAS results. Currently, it contains close to 7 000 publications for &gt;15 000 traits, from which more than 625 000 lead associations have been curated. Additionally, 85 000 full genome-wide summary statistics datasets—containing association data for all variants in the analysis—are available for downstream analyses such as meta-analysis, fine-mapping, Mendelian randomisation or development of polygenic risk scores. As a centralised repository for GWAS results, the GWAS Catalog sets and implements standards for data submission and harmonisation, and encourages the use of consistent descriptors for traits, samples and methodologies. We share processes and vocabulary with the PGS Catalog, improving interoperability for a growing user group. Here, we describe the latest changes in data content, improvements in our user interface, and the implementation of the GWAS-SSF standard format for summary statistics. We address the challenges of handling the rapid increase in large-scale molecular quantitative trait GWAS and the need for sensitivity in the use of population and cohort descriptors while maintaining data interoperability and reusability.
The landscape of immune checkpoint inhibitor clinical trials in glioblastoma: A systematic review
Authors: Schonfeld Ethan , Choi John , Tran Andrew , Kim Lily H , Lim Michael 
Published: November 2024

Abstract

Background
Glioblastoma is characterized by rapid tumor growth and high invasiveness. The tumor microenvironment of glioblastoma is highly immunosuppressive with both intrinsic and adaptive resistance mechanisms that result in disease recurrence despite current immunotherapeutic strategies.

Methods
In this systematic review of clinical trials involving immunotherapy for glioblastoma using ClinicalTrials.gov and PubMed databases from 2016 and onward, we explore immunotherapeutic modalities involving immune checkpoint blockade (ICB).

Results
A total of 106 clinical trials were identified, 18 with clinical outcomes. ICB in glioblastoma has failed to improve overall survival compared to the current standard of care, including those therapies inhibiting multiple checkpoints. Among all immune checkpoint trials, targets included programmed cell death protein-1 (PD-1) (35/48), PD-L1 (12/48), cytotoxic T-lymphocyte-associated protein-4 (6/48), TIGIT (2/48), B7-H3 (2/48), and TIM-3 (1/48). Preliminary results from combination immunotherapies (32.1% of all trials) demonstrated improved treatment efficacy compared to monotherapy, specifically those combining checkpoint therapy with another immunotherapy modality.

Conclusions
Clinical trials involving ICB strategies for glioblastoma have not demonstrated improved survival. Comparison of therapeutic efficacy across trials was limited due to heterogeneity in the study population and outcome operationalization. Standardization of future trials could facilitate comparison across immunotherapy modalities for robust meta-analysis. Current immunotherapy trials have shifted focus toward combination strategies; preliminary results suggest that they are more encouraging than mono-modality immunotherapies. Given the intrinsic heterogeneity of glioblastoma, the utilization of immune markers will be key for the development of future immunotherapy approaches.
Association of Cigarette–E-Cigarette Transitions With Respiratory Symptom Resolution
Authors: Berlowitz Jonathan B , Xie Wubin , Harlow Alyssa F , Kathuria Hasmeena , Benjamin Emelia J , Stokes Andrew C 
Published: November 2024

Abstract

Introduction
Adults increasingly use e-cigarettes for cigarette cessation because of the perceived reduced risk. While e-cigarette use is associated with reduced toxicant exposure compared with smoking, it is unclear whether transitioning from cigarettes to e-cigarettes is associated with resolution of respiratory symptoms.

Methods
Data were obtained from the Population Assessment of Tobacco and Health (PATH) study waves 1–5. US adult participants were separated into observations with cigarette–e-cigarette exposure intervals determined from PATH waves 1–2, 2–3, and 3–4. Observations were included if the participant reported exclusively smoking at baseline and reported a baseline cough or wheeze. Mixed-effect Poisson models measured the association between cigarette–e-cigarette transitions over the two-wave exposure interval (from smoking to nonuse, exclusive e-cigarette use, continued smoking, or dual use) and the reported resolution of the participant’s cough or wheeze.

Results
Among 5210 (3362 unique) observations, transitioning from cigarettes to e-cigarettes was associated with increased rates of wheeze resolution (incidence rate ratio [IRR] = 1.33; 95% confidence interval [CI] = 1.01 to 1.75) but not cough resolution (IRR = 1.18; 95% CI = 0.93 to 1.50) compared with persistent smoking. Cigarette to dual-use transitions were not associated with improvements in symptom resolution, and those who switched to dual use and maintained or increased their smoking intensity had 15% decreased rates of respiratory symptom resolution compared with persistent smoking.

Discussion
E-cigarette-assisted smoking cessation may increase rates of respiratory symptoms resolution among smokers who completely transition to e-cigarettes; however, there is risk for additional harm among those who initiate e-cigarette use without decreasing their smoking intensity.

Implications
Government agencies are increasingly weighing the risks and benefits of e-cigarette-assisted cigarette cessation given the reduced harm associated with e-cigarette use. This study provides novel evidence that completely transitioning from cigarettes to e-cigarettes is associated with increased rates of resolution from self-reported wheeze symptoms. However, risk exists in e-cigarette-assisted cigarette cessation, as those who transitioned from exclusive cigarette smoking to dual use and did not reduce their cigarette smoking intensity had decreased rates of respiratory symptom resolution compared with persistent smokers.
L’allergie aux protéines du lait de vache chez les nourrissons et les enfants
Authors: Sathya Pushpa , Fenton Tanis R 
Published: November 2024

Résumé
L’allergie aux protéines du lait de vache (APLV) est une réaction à médiation immunitaire aux protéines du lait de vache, qui peut toucher de multiples systèmes organiques, y compris le tractus gastro-intestinal. Une réaction induite par les immunoglobulines E (IgE) entraîne l’apparition rapide de symptômes allergiques faciles à reconnaître. Cependant, des réactions tardives (non induites par les IgE ou les cellules) ou mixtes (induites par les IgE et les cellules) entraînent une série de symptômes qui ressemblent à d’autres affections et dont le moment d’apparition et la gravité sont très variables. Il est difficile de déterminer si les symptômes sont attribuables à une APLV à médiation immunitaire, à une réaction non immunologique au lait de vache ou à autre chose que l’exposition au lait de vache, mais il est essentiel d’y parvenir pour proposer une prise en charge efficace. Le tableau clinique de l’APLV non induite par les IgE peut varier, mais cette affection, généralement autorésolutive, disparaît entre l’âge de un et six ans. Il faut éviter les batteries de dosages des immunoglobulines G (IgG) pour déceler les intolérances alimentaires spécifiques aux antigènes qui ne reposent pas sur des données probantes, parce qu’elles peuvent entraîner un surdiagnostic de prétendues intolérances alimentaires. Le surdiagnostic d’APLV peut être responsable de la surutilisation de préparations fortement hydrolysées, ce qui a des répercussions financières importantes pour les familles. Le présent document de principes, qui traite de l’APLV non induite par les IgE ou les cellules, aide les professionnels de la santé à distinguer et reconnaître les diverses réactions au lait de vache, aborde le rôle des tests diagnostiques et fournit des recommandations de prise en charge en fonction des données probantes exemplaires.
Cow’s milk protein allergy in infants and children
Authors: Sathya Pushpa , Fenton Tanis R 
Published: November 2024

Abstract
Cow’s milk protein allergy (CMPA) is an immune-mediated reaction to cow’s milk proteins, which can involve multiple organ systems including the gastrointestinal tract. Immunoglobulin E (IgE)-mediated response results in rapid onset of allergic symptoms that are easily recognizable. However, delayed (i.e., non-IgE/cell-mediated) or mixed (IgE- and cell-mediated) reactions produce a host of symptoms that overlap with other conditions and vary widely in onset and severity. Determining whether symptoms represent immune-mediated CMPA, non-immunologic reaction to cow’s milk, or are unrelated to cow’s milk exposure is challenging yet essential for effective management. While the clinical presentation of non-IgE-mediated CMPA can vary, this condition is usually self-limited and resolves by 1 to 6 years of age. Food antigen-specific immunoglobulin G (IgG) panels that are not evidence-based should be avoided because they can lead to overdiagnosis of presumed food intolerances. Overdiagnosis of CMPA can result in overuse of extensively hydrolyzed formulas and have significant cost implications for families. This statement focuses on delayed non-IgE/cell-mediated CMPA and assists health care providers to distinguish between and identify varied reactions to cow’s milk, discusses the role of diagnostic testing, and provides management recommendations based on best evidence.
A mechanistic integration of hypoxia signaling with energy, redox, and hormonal cues
Authors: Renziehausen Tilo , Chaudhury Rim , Hartman Sjon , Mustroph Angelika , Schmidt-Schippers Romy R 
Published: November 2024

Abstract
Oxygen deficiency (hypoxia) occurs naturally in many developing plant tissues but can become a major threat during acute flooding stress. Consequently, plants as aerobic organisms must rapidly acclimate to hypoxia and the associated energy crisis to ensure cellular and ultimately organismal survival. In plants, oxygen sensing is tightly linked with oxygen-controlled protein stability of group VII ETHYLENE-RESPONSE FACTORs (ERFVII), which, when stabilized under hypoxia, act as key transcriptional regulators of hypoxia-responsive genes (HRGs). Multiple signaling pathways feed into hypoxia signaling to fine-tune cellular decision-making under stress. First, ATP shortage upon hypoxia directly affects the energy status and adjusts anaerobic metabolism. Secondly, altered redox homeostasis leads to reactive oxygen and nitrogen species (ROS and RNS) accumulation, evoking signaling and oxidative stress acclimation. Finally, the phytohormone ethylene promotes hypoxia signaling to improve acute stress acclimation, while hypoxia signaling in turn can alter ethylene, auxin, abscisic acid, salicylic acid, and jasmonate signaling to guide development and stress responses. In this Update, we summarize the current knowledge on how energy, redox, and hormone signaling pathways are induced under hypoxia and subsequently integrated at the molecular level to ensure stress-tailored cellular responses. We show that some HRGs are responsive to changes in redox, energy, and ethylene independently of the oxygen status, and we propose an updated HRG list that is more representative for hypoxia marker gene expression. We discuss the synergistic effects of hypoxia, energy, redox, and hormone signaling and their phenotypic consequences in the context of both environmental and developmental hypoxia.
Combined Surgical Technique of Hyperselective and Partial Motor Neurectomies for Spastic Equinus, Equinovarus, and Claw Toe Deformities
Authors: Wu Kitty Y. , Pino Paula A. , Ryssman Daniel B. , Rhee Peter C. 
Published: November 2024

Background:
Patients with spastic equinus, equinovarus, and claw toe deformities can experience marked pain and functional limitations in the ability to weight-bear comfortably, ambulate efficiently, or mobilize independently. Seen in 80% of patients with cerebral palsy and 18% of patients with stroke (1, 2), the spastic foot and ankle deformities, and its secondary sequelae of static joint contractures, osseous changes, and chronic pain, are unfortunately common.

Methods:
Adult and pediatric patients undergoing combined hyperselective and selective partial motor neurectomies for varus or claw toe deformities were reviewed. Patient demographics and complications were recorded. Pre- and postoperative Modified Ashworth Scale scores were compared.

Results:
Twenty-three patients (16 adults and seven pediatric) met inclusion criteria and were included in analysis. At early 6-month follow-up, the mean preoperative Modified Ashworth Score of 2.8 in adult patients and 3.0 in pediatric patients decreased to 0.6 postoperatively. Complications in three adult patients included one patient with temporary dysesthesias to the plantar foot, one with a popliteal abscess requiring incision and drainage, and one superficial wound dehiscence that was managed conservatively.

Conclusions:
A combined technique of hyperselective and partial motor neurectomies are effective in decreasing tone in the correction of spastic foot and ankle deformities in both adult and pediatric patients in short-term 6-month follow-up.
Corporal Filler HD, a Minimally Invasive Technique for Male Body Contouring: A Pilot Study
Authors: Dziabas Daniel , Kasai Matheus , Viana Renata 
Published: November 2024

Background:
The perception of body image is highly influenced by culture and society. Lean, more muscular, and strong bodies are usually pursued by men. Body aesthetics procedures have become popular, and minimally invasive procedures have been used to achieve body image satisfaction.

Methods:
This article describes a technique that utilizes hyaluronic acid filler to enhance muscular contours in the abdominal and pectoral regions. The procedure involves injecting hyaluronic acid filler at a level anterior to the pectoralis major and rectus abdominis muscles through marked entry points, creating an illusion of light and shadow that accentuates muscle definition. Additionally, the iliac region can be addressed to enhance the oblique muscles.

Results:
The results are illustrated with pre- and postprocedure images, demonstrating a significant aesthetic improvement, high patient satisfaction, and absence of serious adverse events.

Conclusions:
This minimally invasive technique is suitable for patients with a low body fat percentage and a desire to enhance muscle definition, providing immediate results with no downtime. Although the scientific literature on filler applications in the thoracoabdominal region is limited, this study demonstrates that precision in minimally invasive procedures can yield highly satisfactory outcomes.
Quantifying Plastic and Reconstructive Surgery Engagement in the Evolution of ICD-10 Codes
Authors: Donaldson Rachel , Hallman Taylor G. , Qureshi Umer , Soltani Hannah , Arcelona Christian , Gutowski Kristof S. , Bajaj Anitesh , Gosain Arun K. 
Published: November 2024

Background:
International Classification of Diseases (ICD)-10 code specificity is important for detailed diagnostic documentation. Insufficient coding granularity in plastic surgery may hinder accurate clinical documentation, impacting education, research, and patient care. This study examines ICD-10 code modification efforts by plastic surgeons and plastic surgery organizations within the last decade, subsequently detailing the formal proposal process and highlighting potential areas where coding modifications may be explored.

Methods:
A retrospective review of all modification proposals presented to the ICD Coordination and Maintenance Committee from March 2013 to March 2023 was conducted. Plastic surgery-related proposals were identified and evaluated for successful implementation. These results were compared to those of other specialties using Fisher exact tests and 2-tailed t tests.

Results:
A total of 472 unique proposals were identified and reviewed. Surgeons and/or surgical organizations contributed to 111 (23.5%) novel proposals, 41 (36.9%) of which were initiated by surgeons. Nine surgical specialties and 14 supporting organizations were represented. The success rate for all surgical-related proposals was 85.6%, with an average time to implementation of 24.7 months. Only 2 (1.8%) of all surgical-related proposals pertained to plastic surgery, both of which were successfully implemented.

Conclusions:
Though a few plastic surgeons have taken advantage of the ICD code revision process within the last decade, the high overall success rate for surgical-related proposals suggests that this seems to be a feasible method by which plastic surgeons and plastic surgery organizations can bring about useful coding changes that meaningfully impact clinical practice.