bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anisotropic Kirchhoff pre-stack depth migration at the COSC-1 borehole, central Sweden
Authors: Simon H , Buske S , Hedin P , Juhlin C , Krauß F , Giese R 
Published: June 2019

SUMMARYA remarkably well preserved representation of a deeply eroded Palaeozoic orogen is found in the Scandinavian Caledonides, formed by the collision of the two palaeocontinents Baltica and Laurentia. Today, after 400 Ma of erosion along with uplift and extension during the opening of the North Atlantic Ocean, the geological structures in central western Sweden comprise far transported allochthonous units, the underlying Precambrian crystalline basement, and a shallow west-dipping décollement that separates the two and is associated with a thin layer of Cambrian black shales. These structures, in particular the Seve Nappes (upper part of the Middle Allochthons), the Lower Allochthons and the highly reflective basement are the target of the two approximately 2.5 km deep fully cored scientific boreholes in central Sweden that are part of the project COSC (Collisional Orogeny in the Scandinavian Caledonides). Thus, a continuous 5 km tectonostratigraphic profile through the Caledonian nappes into Baltica’s basement will be recovered. The first borehole, COSC-1, was successfully drilled in 2014 and revealed a thick section of the seismically highly reflective Lower Seve Nappe. The Seve Nappe Complex, mainly consisting of felsic gneisses and mafic amphibolites, appears to be highly anisotropic. To allow for extrapolation of findings from core analysis and downhole logging to the structures around the borehole, several surface and borehole seismic experiments were conducted. Here, we use three long offset surface seismic profiles that are centred on the borehole COSC-1 to image the structures in the vicinity of the borehole and below it. We applied Kirchhoff pre-stack depth migration, taking into account the seismic anisotropy in the Seve Nappe Complex. We calculated Green’s functions using an anisotropic eikonal solver for a VTI (transversely isotropic with vertical axis of symmetry) velocity model, which was previously derived by the analysis of VSP (Vertical Seismic Profile) and surface seismic data. We show, that the anisotropic results are superior to the corresponding isotropic depth migration. The reflections appear significantly more continuous and better focused. The depth imaging of the long offset profiles provides a link between a high-resolution 3-D data set and the regional scale 2-D COSC Seismic Profile and complements these data sets, especially in the deeper parts below the borehole. However, many of the reflective structures can be observed in the different data sets. Most of the dominant reflections imaged originate below the bottom of the borehole and are situated within the Precambrian basement or at the transition zones between Middle and Lower Allochthons and the basement. The origin of the deeper reflections remains enigmatic, possibly representing dolerite intrusions or deformation zones of Caledonian or pre-Caledonian age.
SIC-POVMs and the Stark Conjectures
Authors: Kopp Gene S 
Published: June 2019

Abstract
The existence of $d^2$ pairwise equiangular complex lines [equivalently, a symmetric informationally complete positive operator-valued measure (SIC-POVM)] in $d$-dimensional Hilbert space is known only for finitely many dimensions $d$. We prove that, if there exists a set of real units in a certain ray class field (depending on $d$) satisfying certain algebraic properties, a SIC-POVM exists, when $d$ is an odd prime congruent to 2 modulo 3. We give an explicit analytic formula that we expect to yield such a set of units. Our construction uses values of derivatives of zeta functions at $s=0$ and is closely connected to the Stark conjectures over real quadratic fields. We verify numerically that our construction yields SIC-POVMs in dimensions 5, 11, 17, and 23, and we give the first exact SIC-POVM in dimension 23.
Determinants of place of death for end-stage cancer patients: evidence from China
Authors: Li Zhong , Jiang Shan , Xu Chengzhong , Lu Fangfang , He Ruibo , Pan Zijin , Zhang Pei , Zhang Liang 
Published: June 2019

Abstract

Objective
To determine factors influence place of death (POD) for end-stage cancer patients and investigate how the healthcare utilization mediates on the effect of socioeconomic status (SES) on POD.

Design
A population-based, retrospective study from July 2015 to June 2017.

Setting
Yichang, China.

Participants
894 end-stage cancer patients.

Main outcome measure
POD.

Results
Patients of hospital death experience more inpatient hospitalization services (IHS) and emergency department visits. Patients enrolled in the New Rural Cooperative Medical Scheme (OR = 7.60, P &lt; 0.001) and Urban Employee Basic Medical Insurance (OR = 28.0, P &lt; 0.001) have higher rates of hospital death than those in the Urban Resident-based Basic Medical Insurance. Living with spouse (OR = 1.72, P = 0.019) and receiving higher education (OR = 1.92, P = 0.004), increase the likelihood of hospital death by 72% and 92%, respectively. The probability of hospital death will increase by 14% and decrease by 4% per IHS and outpatient services occur, respectively. Outpatient services (Z = −2.28, P &lt; 0.001), and IHS (Z = 2.17, P &lt; 0.001) mediate 1.81% and 1.89%, respectively, of the effect of health insurance on POD. The overall effect of the mediators is non-statistically significant (Z = 0.09, P = 0.825).

Conclusion
POD is mainly driven by SES. The relationship between health insurance and POD is partly mediated by outpatient services and IHS, respectively. The results corroborated that hospital and home services should be coherently bridged. Furthermore, benefit packages for end-stage cancer patients could be redesigned.
DQueST: dynamic questionnaire for search of clinical trials
Authors: Liu Cong , Yuan Chi , Butler Alex M , Carvajal Richard D , Li Ziran Ryan , Ta Casey N , Weng Chunhua 
Published: June 2019

Abstract

Objective
Information overload remains a challenge for patients seeking clinical trials. We present a novel system (DQueST) that reduces information overload for trial seekers using dynamic questionnaires.

Materials and Methods
DQueST first performs information extraction and criteria library curation. DQueST transforms criteria narratives in the ClinicalTrials.gov repository into a structured format, normalizes clinical entities using standard concepts, clusters related criteria, and stores the resulting curated library. DQueST then implements a real-time dynamic question generation algorithm. During user interaction, the initial search is similar to a standard search engine, and then DQueST performs real-time dynamic question generation to select criteria from the library 1 at a time by maximizing its relevance score that reflects its ability to rule out ineligible trials. DQueST dynamically updates the remaining trial set by removing ineligible trials based on user responses to corresponding questions. The process iterates until users decide to stop and begin manually reviewing the remaining trials.

Results
In simulation experiments initiated by 10 diseases, DQueST reduced information overload by filtering out 60%–80% of initial trials after 50 questions. Reviewing the generated questions against previous answers, on average, 79.7% of the questions were relevant to the queried conditions. By examining the eligibility of random samples of trials ruled out by DQueST, we estimate the accuracy of the filtering procedure is 63.7%. In a study using 5 mock patient profiles, DQueST on average retrieved trials with a 1.465 times higher density of eligible trials than an existing search engine. In a patient-centered usability evaluation, patients found DQueST useful, easy to use, and returning relevant results.

Conclusion
DQueST contributes a novel framework for transforming free-text eligibility criteria to questions and filtering out clinical trials based on user answers to questions dynamically. It promises to augment keyword-based methods to improve clinical trial search.
Carbon-ion irradiation overcomes HPV-integration/E2 gene-disruption induced radioresistance of cervical keratinocytes
Authors: Arians Nathalie , Nicolay Nils Henrik , Brons Stephan , Koerber Stefan Alexander , Jaschke Christine , Vercruysse Marco , Daffinger Sigrid , Rühle Alexander , Debus Jürgen , Lindel Katja 
Published: June 2019

AbstractTo date, only few data exist on mechanisms underlying the human papillomavirus (HPV)-associated irradiation response. It has been suggested, that the viral E2 gene plays an important role in that context. The aim of the current study is to compare the effect of photon- and carbon-ion (12C)-radiation therapy (RT) on cells with different HPV and E2 gene status. We hypothesized that 12C-RT might overcome the radioresistance of E2 gene-disrupted cells.We analyzed four different cell lines that differed in HPV status or E2 gene status. Cells were irradiated with either photons or 12C. Clonogenic survival, cell cycle and expression of Rb and p53 were analyzed.Radiosensitivity seemed to be dependent on E2 gene status and type of RT. 12C-RT led to lower surviving fractions, indicating higher radiosensitivity even in cells with disrupted E2 gene. The observed relative biological effectiveness (RBE) of 12C-RT for C33a/Caski and W12/S12 was 1.3/4 and 2.7/2.5, respectively. Cell cycle regulation after both photon- and 12C-RT was dependent on HPV status and on E2 gene status. Furthermore, the effect of RT on expression of p53 and Rb seemed to be dependent on E2 gene status and type of RT.We showed that 12C-RT overcomes HPV-integration induced radioresistance. The effect of RT on cell cycle regulation as well as on expression of p53 and Rb seemed to be dependent on HPV status, E2 gene status and type of RT. Differences in Rb expression and cell cycle regulation may play a role for enhanced radiosensitivity to 12C-RT of cells with disrupted E2 gene.
Chinese Text Project: A dynamic digital library of premodern Chinese
Authors: Sturgeon Donald 
Published: June 2019

AbstractThis article presents technical approaches and innovations in digital library design developed during the design and implementation of the Chinese Text Project, a widely-used, large-scale full-text digital library of premodern Chinese writing. By leveraging a combination of domain-optimized Optical Character Recognition, a purpose-designed crowdsourcing system, and an Application Programming Interface (API), this project simultaneously provides a sustainable transcription system, search interface and reading environment, as well as an extensible platform for transcribing and working with premodern Chinese textual materials. By means of the API, intentionally loosely integrated text mining tools are used to extend the platform, while also being reusable independently with materials from other sources and in other languages.
Hyperfine excitation of NS+ due to para-H2(j = 0) impact
Authors: Bop Cheikh T 
Published: June 2019

ABSTRACT
Sulphur bearing nitrogenous compounds have been observed in space over this last decade. Modelling their abundances has been done using rate coefficients of isoelectronic molecules. In order to satisfy the astrophysical precision required, we report the actual rate coefficients of NS+ induced by collision with the most abundant interstellar species (para-H2). Considering the 23 low-lying rotational levels of NS+, we were able to compute the (hyperfine) rate coefficients up to 100 K. These latter were carried out by averaging cross-sections over the Maxwell–Boltzmann velocity distribution. The state-to-state inelastic cross-sections were determined in the quantum mechanical close coupling approach for total energies ranging up to 1400 cm−1. These dynamic data result from a four dimensional potential energy surface (4D-PES) which was spherically averaged over the H2 orientations. The 4D-PES was calculated using the explicitly correlated coupled cluster method with simple, double, and non-iterative triple excitation (CCSD(T)–F12) connected to the augmented–correlation consistent–polarized valence triple zeta Gaussian basis set (aug–cc–pVTZ). The so-averaged PES presents a very deep well of 596.72 cm−1 at R = 5.94 a0 and θ1 = 123.20°. Discussions on the propensity rules for the (hyperfine) rate coefficients were made and they are in favour of (Δj = ΔF) Δj = 1 transitions. The results presented here may be crucially needed in order to accurately model the NS+ abundance in space. In addition, we expect that this paper will encourage investigations on the sulphur bearing nitrogenous compounds.
Black hole – Galaxy correlations in simba
Authors: Thomas Nicole , Davé Romeel , Anglés-Alcázar Daniel , Jarvis Matt 
Published: June 2019

ABSTRACT
We examine the co-evolution of galaxies and supermassive black holes in the simba cosmological hydrodynamic simulation. simba grows black holes via gravitational torque-limited accretion from cold gas and Bondi accretion from hot gas, while feedback from black holes is modelled in radiative and jet modes depending on the Eddington ratio (fEdd). simba shows generally good agreement with local studies of black hole properties, such as the black hole mass–stellar velocity dispersion (MBH–σ) relation, the black hole accretion rate versus star formation rate (BHAR–SFR), and the black hole mass function. MBH–σ evolves such that galaxies at a given MBH have higher σ at higher redshift, consistent with no evolution in MBH–M⋆. For $M_{\rm BH}\lesssim 10^8\, {\rm M}_{\odot }$, fEdd is anticorrelated with MBH since the BHAR is approximately independent of MBH, while at higher masses fEdd–MBH flattens and has a larger scatter. BHAR versus SFR is invariant with redshift, but fEdd drops steadily with time at a given MBH, such that all but the most massive black holes are accreting in a radiatively efficient mode at $z\gtrsim 2$. The black hole mass function amplitude decreases with redshift and is locally dominated by quiescent galaxies for MBH > 108 M⊙, but for $z\gtrsim 1$ star-forming galaxies dominate at all MBH. The z = 0 fEdd distribution is roughly lognormal with a peak at $f_{\rm Edd}\lesssim 0.01$ as observed, shifting to higher fEdd at higher redshifts. Finally, we study the dependence of black hole properties with H i content and find that the correlation between gas content and SFR is modulated by black hole properties, such that higher SFR galaxies at a given gas content have smaller black holes with higher fEdd.
The possible hierarchical scales of observed clumps in high-redshift disc galaxies
Authors: Behrendt M , Schartmann M , Burkert A 
Published: June 2019

ABSTRACTGiant clumps on ∼kpc scales and with masses of $10^8\rm {-}10^9 \, \mathrm{M_{\odot }}$ are ubiquitous in observed high-redshift disc galaxies. Recent simulations and observations with high spatial resolution indicate the existence of substructure within these clumps. We perform high-resolution simulations of a massive galaxy to study the substructure formation within the framework of gravitational disc instability. We focus on an isolated and pure gas disc with an isothermal equation of state with T = 104 K that allows capturing the effects of self-gravity and hydrodynamics robustly. The main mass of the galaxy resides in rotationally supported clumps which grow by merging to a maximum clump mass of $10^8 \, \mathrm{M_{\odot }}$ with diameter ∼120 pc for the dense gas. They group to clump clusters (CCs) within relatively short times ($\ll 50 \, \mathrm{Myr}$), which are present over the whole simulation time. We identify several mass and size scales on which the clusters appear as single objects at the corresponding observational resolution between ${\sim } 10^8 \,\rm{and}\, 10^9 \, \mathrm{M_{\odot }}$. Most of the clusters emerge as dense groups and for larger beams they are more likely to be open structures represented by a single object. In the high-resolution runs higher densities can be reached, and the initial structures can collapse further and fragment to many clumps smaller than the initial Toomre length. In our low-resolution runs, the clumps directly form on larger scales 0.3–1 kpc with $10^8\rm {-}10^9 \, \mathrm{M_{\odot }}$. Here, the artificial pressure floor which is typically used to prevent spurious fragmentation strongly influences the initial formation of clumps and their properties at very low densities.
Body Perception Disturbance and Pain Reduction in Longstanding Complex Regional Pain Syndrome Following a Multidisciplinary Rehabilitation Program
Authors: Lewis Jennifer S , Kellett Sara , McCullough Ryan , Tapper Ashley , Tyler Chelsey , Viner Maria , Palmer Shea 
Published: June 2019

Abstract

Objective
Clinical guidelines for the treatment of complex regional pain syndrome recommend multidisciplinary rehabilitation, yet limited evidence exists to support the effectiveness of this approach. Body perception disturbance, a common and debilitating feature of complex regional pain syndrome, is recommended by guidelines as important to treat. However, no study has yet explored whether disturbances change in response to multidisciplinary rehabilitation. We aimed to determine whether there is a change in body perception disturbance and pain following a two-week multidisciplinary rehabilitation program for complex regional pain syndrome.

Methods
Retrospective clinical data from complex regional pain syndrome patients who completed the program between September 2014 and December 2016 were extracted and anonymized. Data collected pre- and post rehabilitation comprising the Bath Body Perception Disturbance scale and a pain intensity numerical rating scale were analyzed.

Results
Thirty complete data sets were analyzed from a sample of 50 consecutive patient records. After the program, there was a significant reduction in body perception disturbance (P < 0.0001), strength of negative emotional feelings (P < 0.0001), and pain (P = 0.0038). There was a significant correlation between a change in disturbance and pain (r = 0.44, P = 0.024). No relationship was found between the duration of symptoms and changes in disturbance (r = 0.04, P = 0.82).

Conclusions
This study provides evidence that both body perception disturbance and pain reduce after rehabilitation. Findings suggest that targeting these disturbances may be important in reducing pain and may be a potentially useful measure for recovery. Controlled trials are required to confirm the effectiveness of rehabilitation and determine what factors are responsible for these reductions.
Public health professionals’ perceptions of the capacity of China’s CDCs to address emerging and re-emerging infectious diseases
Authors: Tong Michael Xiaoliang , Hansen Alana , Hanson-Easey Scott , Xiang Jianjun , Cameron Scott , Liu Qiyong , Liu Xiaobo , Sun Yehuan , Weinstein Philip , Han Gil-Soo , Mahmood Afzal , Bi Peng 
Published: June 2019

Abstract

Background
China’s capacity to control and prevent emerging and re-emerging infectious diseases is critical to the nation’s population health. This study aimed to explore the capacity of Centers for Disease Control and Prevention (CDCs) in China to deal with infectious diseases now and in the future.

Methods
A survey was conducted in 2015 among 973 public health professionals at CDCs in Beijing and four provinces, to assess their capacity to deal with emerging and re-emerging infectious diseases.

Results
Although most professionals were confident with the current capacity of CDCs to cope with outbreaks, nearly all indicated more funding was required to meet future challenges. Responses indicated that Yunnan Province faced more challenges than Anhui, Henan and Liaoning Provinces in being completely prepared and able to deal with outbreaks. Participants aged 20–39 years were more likely than those aged 40 and over to believe strategies such as interdisciplinary and international collaborations for disease surveillance and control, would assist capacity building.

Conclusion
The capacity of China’s CDCs to deal with infectious diseases was excellent. However, findings suggest it is imperative to increase the number of skilled CDC staff, financial support, and strengthen county level staff training and health education programs.
Family Firms and Labor Market Regulation
Authors: Bennedsen Morten , Huang Sterling , Wagner Hannes F , Zeume Stefan 
Published: June 2019

Abstract
In a panel across twenty-eight countries over 10 years, we show that family firms on average enjoy performance advantages over nonfamily firms only when labor markets are less regulated. We confirm this result in a matched firm sample using a survey-based instrument as a family control. Furthermore, family firms exhibit lower variation in employment levels in less-regulated labor markets, supporting the notion that labor relations drive family firms’ performance advantages. Our results are consistent with the notion that both family ownership and labor market reforms provide employment protection and thus partly substitute as governance mechanisms.
Received December 17, 2018; editorial decision April 3, 2019 by Editor Andrew Ellul.
Secret trusts and testamentary freedom
Authors: Cheung Tommy 
Published: June 2019

Abstract
Secret trusts are a mystery because no theory perfectly explains why the court enforces them when they do not comply with the statutory formalities of wills. This article argues that secret trusts are inter vivos express trusts. If secret trusts fulfil their formalities, the courts will enforce them because they reflect the testator’s intentions of disposing his/her properties at death, sharing the same policy considerations of the Wills Act 1837. This article illustrates how equity facilitates the validity of secret trusts, whilst also limiting its scope to give the courts guidance on when to enforce them to preserve testamentary freedom.
Effects of different moisture and temperature levels on Salmonella survival in poultry fat
Authors: Trinetta Valentina , McDaniel Austin , Magossi Gabriela , Yucel Umut , Jones Cassandra 
Published: June 2019

Abstract
Fat products have been historically thought to have too low water activity to harbor pathogens. However, it has been recently reported that high moisture levels in fats may lead to Salmonella presence and growth. Limited research on strategies to eliminate pathogens in these environments is available, and the mechanisms contributing to microbial presence and growth are not yet well understood. The purpose of this research was to evaluate the effects of moisture levels and storage temperatures on the growth and survival of Salmonella in poultry fat. Samples were stored for 7 d at 48°C or 76°C and remaining Salmonella was evaluated. When poultry fat was challenged with a wet high inoculum, more than a 4 log CFU/mL difference in Salmonella population was observed with 1% and 3% moisture levels at 48°C after 5 d (P &lt; 0.05). No differences between moisture levels (P &gt; 0.05) were observed when samples were tested with a wet low inoculum. Counts below detectable limits were observed after 24 h in samples challenged at 76°C, regardless of inoculum level. When poultry fat was stored at 48°C and inoculated with low levels of Salmonella spp., bacterial growth was influenced only by time (P &lt; 0.05) and not affected (P &gt; 0.05) by moisture level. However, when poultry fat was stored at 48°C and inoculated with high levels of Salmonella spp., bacterial decrease was easier (P &lt; 0.05) in samples containing greater moisture. This research suggests that residual moisture in containers during transportation of poultry fat largely does not affect Salmonella spp. growth.