bluuebunny/crossref_metadata_2025_split huggingface dataset:
Secrets of Lighting: Library Book Stack Illumination and Its Influences on Readers’ Book-Searching Behaviors
Authors: Su Wencheng , Lu Zhangping , Lu Wenqing , Li Rui 
Published: March 2019

Abstract
Book stack illuminance was recorded by a luminometer from September 2016 through September 2017 based on tracking-observation in two libraries at the University of Illinois at Urbana and Champaign in the US and the Jiangsu University Library in China. Independent-samples T test and one-way analysis of variance were used for records data analysis. Further, an experiment was designed to measure the effects of book stack lighting environment on readers’ book-searching behaviors. Independent-samples T test was used for experiment data analysis. It was found that the seasonal illuminance of book stacks changed irregularly, which meant that two hypotheses (1 and 2) central to this study were not fully supported, and the day-night illumination differences on the stacks was significant in UIUC libraries for three seasons, and completely significant in JSU Library. In the course of behavior experiments, stack lighting had no significant effect on American participants’ searching performance, while the results in the library of China were diametrically opposite. Therefore, the lighting system in book stacks should be optimized through choosing the appropriate light sources, adjusting the approaches to book stack lighting and, even more, considering readers’ expectation and perception during library lighting designing, so as to increase their efficiency in book-searching.
Computed tomography findings in patients with Samter’s Triad: an observational study
Authors: Kim Min Bum , Lim Gil Chai , Park Jin A , Kim Yoo Suk , Kim Jeong Hong , Kang Ju Wan 
Published: March 2019

Abstract
Samter’s Triad is a disorder characterized by chronic rhinosinusitis (CRS) with nasal polyps (NPs), asthma, and intolerance to cyclooxygenase-1 inhibitors. However, there have been no studies investigating the prediction of Samter’s Triad using imaging findings. Therefore, the authors aimed to investigate whether there is a difference in computed tomography (CT) findings between patients who have CRS with NPs and those with Samter’s Triad. Patients were classified into a CRS group and a Samter group. Opacification was measured using data from CT scans by scoring each sinus on a numerical rating scale ranging from 0 to 4. The opacification scores of the ethmoid and frontal sinuses were significantly higher in the Samter’s Triad group. Furthermore, Samter’s Triad was more common in patients who scored ≤ 2 for maxillary opacification (7/16) than in those who scored ≥3 (4/45, p=0.005). Patients with Samter’s Triad exhibited a tendency toward higher opacification scores for the ethmoid and frontal sinuses, with a relatively lower opacification score for the maxillary sinus. These findings could be helpful in distinguishing patients with Samter’s Triad from those who have CRS with NPs, and to plan treatment strategies without having to perform additional laboratory or radiological tests.
A spinal subdural hematoma induced by guidewire-based lumbar drainage in a patient with ruptured intracranial aneurysms
Authors: Qi Meng , Huang Tao , Xu Lei , Wang Ning , Zhang Peipei , Hu Xi 
Published: March 2019

Abstract
We present a rare case of spinal subdural hematoma induced by guidewire-based lumbar drainage in a subarachnoid hemorrhage patient with a ruptured intracranial aneurysm. Decreased muscle strength and muscle tension of bilateral lower limbs were noted, and an MRI confirmed the spinal subdural hematoma from the sacral to the thoracic segments. The spinal subdural hematoma evacuation and spinal canal decompression were performed by laminectomy. However, the patient did not benefit from the surgery and developed lower limb muscle atrophy. The complication of the spinal subdural hematoma after lumbar drainage is extremely rare; only limited approaches are available for the treatment of spinal hematoma to improve the outcome and avoid severe consequences. Thus, the present case might suggest refraining from use of a guidewire during lumbar drainage for the prevention of spinal subdural hematoma and close observation of the related symptoms and signs for the early detection of spinal hematoma after the procedure. In addition, full decompression can be performed by complete hematoma evacuation and laminectomy of related segments for the treatment of spinal subdural hematoma induced by lumbar drainage.
High expression B3GAT3 is related with poor prognosis of liver cancer
Authors: Zhang Yan-li , Ding Chao , Sun Lei 
Published: March 2019

Abstract
Liver cancer is one of the most malignant tumors with poor prognosis. Finding molecular markers that can predict prognosis is very important for the treatment of liver cancer. The present research is trying to find a new biomarker for human liver cancer. The analysis of abnormal expression genes and prognosis value on liver cancer by Gene Expression Profiling Interactive Analysis (GEPIA) database, the Pathology Atlas of the Human Protein Atlas (HPA), and Kaplan Meier-plotter (KM plotter), proved that B3GAT3 might be one of the important candidates. Furthermore, we investigated the specific role of B3GAT3 on liver cancer through the transfection of B3GAT3 siRNA in HepG2 cells. The proliferation was detected using CCK8, and migration and invasion were determined using Transwell assay. Our results proved that knockdown of B3GAT3 inhibited the proliferation, migration, and invasion. Moreover, B3GAT3 knockdown inhibited the expression of EMT related proteins, N-cad, Snail, and Twist, while promoting the expression of E-cad, suggesting that B3GAT3 knockdown reversed the EMT process of liver cancer cells. In conclusion, overexpressed B3GAT3 promotes the process of tumor EMT, which is an independent prognostic marker to predict the prognosis of liver cancer and might be a potential new target for liver cancer therapy.
Oncoprotein LAMTOR5 activates GLUT1 via upregulating NF-κB in liver cancer
Authors: Zhou Jing , Li Yajun , Li Danhua , Liu Zhi , Zhang Jie 
Published: March 2019

Abstract

Objective
Accumulating reports reveal that serving as an oncogenic factor LAMTOR5 is involved in the progression of many specific cancers. Glucose transporter 1 (GLUT1) is frequently identified in many cancers. However, it remains unexplored whether GLUT1 plays a role in LAMTOR5-enhanced liver cancer. Here, we aim to decipher the function of LAMTOR5 in the regulation of GLUT1 in liver cancer.

Methods
The effect of LAMTOR5 on GLUT1 was analyzed using Western blotting and RT-PCR assay. Dose-increased over-expression or silencing of LAMTOR5 was performed through transient transfection. LAMTOR5-activated GLUT1 promoter was revealed by luciferase reporter assay. The regulation of GLUT1 by LAMTOR5/NF-κB was examined via Western blotting and luciferase reporter assays.

Results
The data showed that in liver cancer cells under the administration with dose-increased LAMTOR5, the level of mRNA and protein of GLUT1 was obviously raised. Our data revealed that the activities of GLUT1 promoter were induced by LAMTOR5. Then, we found that the elevation of GLUT 1 mediated by LAMTOR5 slowed when the inhibitor or siRNAs of NF-κB was introduced into the liver cancer cells. Conclusion. LAMTOR5 is responsible for the activation of GLUT1 via transcription factor NF-κB in liver cancer.
Laser-written colours on silver: optical effect of alumina coating
Authors: Guay Jean-Michel , Calà Lesina Antonino , Killaire Graham , Gordon Peter G. , Hahn Choloong , Barry Sean T. , Ramunno Lora , Berini Pierre , Weck Arnaud 
Published: March 2019

Abstract
In this paper we discuss the optical response of laser-written plasmonic colours on silver coated via the atomic layer deposition of alumina. These colours are due to nanoparticles distributed on a flat surface and on a surface with periodic topographical features (i.e. ripples). The colours are observed to shift with increasing alumina film thickness. The colours produced by surfaces with ripples recover their original vibrancy and hue after the deposition of film of thickness ~60 nm, while colours arising from flat surfaces gradually fade and never recover. Analysis of the surfaces identifies periodic topographical features to be responsible for this behaviour. Finite-difference time-domain simulations unravel the role played by the alumina thickness in colour formation and confirm the rotations and recovery of colours for increasing alumina thickness. The coloured surfaces were evaluated for applications in colourimetric and radiometric sensing showing large sensitivities of up to 3.06/nm and 3.19 nm/nm, respectively. The colourimetric and radiometric sensitivities are observed to be colour dependent.
Crystal structure of 5-(5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl)-N-phenyl-2-amine, C23H16ClN5O
Authors: Alotaibi Mohammad Hayal , Mohamed Hanan A. , Abdel-Wahab Bakr F. , Hegazy Amany S. , Kariuki Benson M. , El-Hiti Gamal A. 
Published: March 2019

Abstract
C23H16ClN5O, monoclinic, P21/c (no. 14), a = 10.0503(6) Å, b = 17.5265(9) Å, c = 22.8763(16) Å, β = 91.554(6)°, V = 4028.1(4) Å3, Z = 8, R
gt(F) = 0.0748, wR
ref(F
2) = 0.2274, T = 296(2) K.
The crystal structure of 2-(4-chloro-2,6-dinitrophenyl)-1-(4-chloro)diazene oxide, C12H6Cl2N4O5
Authors: Cao Junyan , Wang Jianlong , Chen Jun , Zhang Xiyu , Qin Zhiang 
Published: March 2019

Abstract
C12H6Cl2N4O5, triclinic, P1̄ (no. 2), a = 8.1022(14) Å, b = 9.6916(17) Å, c = 10.2476(17) Å, α = 78.346(4)°, β = 68.657(4)°, γ = 71.167(4)°, V = 706.1(2) Å3, Z = 2, R
gt(F) = 0.0356, wR
ref(F
2) = 0.1109, T = 120 K.
Crystal structure of methyl 4-acetoxybenzoate, C10H10O4
Authors: Li-Min Fang , Jian-Ping Huang , Jian-Cheng Dai , Xu-Liang Nie , Chang-Xiang Liu , Nian-Qian Kang , Lin Huang 
Published: March 2019

Abstract
C10H10O4, monoclinic, C2/c (no. 15), a = 25.400(4) Å, b = 5.9738(10) Å, c = 12.746(2) Å, β = 94.318(2)°, V = 1928.5(6) Å3, Z = 8, R
gt(F) = 0.0434, wR
ref(F
2) = 0.1276, T = 296(2) K.
Non-equilibrium Phase Transitions in 2D Small-World Networks: Competing Dynamics
Authors: Liu Wei , Yan Zhengxin , Zhou Gaoliang 
Published: March 2019

Abstract
This article offers a detailed analysis of the Ising model in 2D small-world networks with competing Glauber and Kawasaki dynamics. The non-equilibrium stationary state phase transitions are obtained in these networks. The phase transitions are discussed, and the phase diagrams are obtained via Monte Carlo simulations and finite-size analyzing. We find that as the addition of links increases the phase transition temperature increases and the transition competing probability of tricritical point decreases. For the competition of the two dynamics, ferromagnetic to anti-ferromagnetic phase transitions and the critical endpoints are found in the small-world networks.
Growth, Vibrational, Optical, Mechanical and DFT Investigations of an Organic Nonlinear Optical Material – Phenylurea
Authors: Dinesh Marappan , Maadeswaran Palanisamy , Ho Mon-Shu , Babu Balraj , Chandrasekar Sivakumar 
Published: March 2019

Abstract
In this work, combined experimental and computational studies of an organic nonlinear optical material, phenylurea (PU), are reported. Optical quality single crystal of PU, was successfully grown by the slow evaporation method. The unit cell parameters of the grown PU crystal belong to the monoclinic system and these belong to the non-centrosymmetric (NCS), P21, space group. Morphology of the crystal was indexed and it reveals its 14 distinct faces. Vibrational modes of PU functional groups were assigned successfully using FTIR and Raman spectrum. The grown crystal exhibits low cutoff wavelength at UV region with good optical transparency and blue wavelength emission. The preliminary measurements confirmed that second harmonic generation (SHG) activity (∼7.6 KDP and ∼2.2 urea) with excellent laser induced threshold damage (LDT) having a value of 2.92 GW/cm2 (∼1.95 urea). TG/DTA analysis shows that endothermic nature of grown crystal with thermal stability up to 154 °C. The Vickers micro hardness test confirms soft material behavior of PU crystal and it was further explored by crystal void percentage calculation. Electrical properties such as dielectric and photoconductivity measurements were carried out for grown crystal. Furthermore, density functional theory (DFT) studies such as Mulliken charge distribution, frontier molecular orbitals (FMOs), molecular electrostatic potential (MEP) map and first order hyperpolarizability (β) were determined to probe the structure-property relationship. These results suggest that PU single crystal can be a better alternate for urea in NLO applications.
4-Acetamidophenol Binding Mechanism with DNA by UV-Vis and FTIR Techniques Based on Binding Energy, LUMO and HOMO Orbitals and Geometry of Molecule
Authors: Habib Aqsa , Bhatti Haq Nawaz , Iqbal Munawar , Asim Sadia , Mansha Asim 
Published: March 2019

Abstract
Present study was conducted to appraise the interaction mechanism of 4-acetamidophenol (4-AP) with DNA based on UV-Vis and FTIR techniques based on binding energy, isolated atomic energy, LUMO and HOMO orbitals gap and geometry of molecule. Analysis revealed the groove binding and intercalation mode of interaction between 4-AP and DNA since hyperchromic and bathochromic shifts were observed in response of interaction of DNA. The planar part of interacting molecule intercalated with DNA and non-planar part of 4-acetamidophenol bounded with DNA (groove binding). The constants for binding between 4-AP and DNA were calculated and 20.12 × 103 mol−1 dm3 binding constant was recorded at pH 4.7, whereas this value was 5.32 × 103 mol−1 dm3 for the pH 7.4. The binding constant value for interaction of 4-AP with DNA revealed the possibility of oral administration of 4-AP. The 4-AP binding with DNA is spontaneous process, which was confirmed from negative value of free energy at room temperature. FTIR study revealed that C–H and C=C (aromatic) functional groups were involved in binding at pH 4.7 and C=O (amide) was involved in groove binding, whereas C–H (aromatic) was responsible for intercalation at pH 7.4 and C–H (alkaline) and C=O (amide) were responsible for groove binding at pH 4.7.
Gas-Phase Reactions of the Group 10 Organometallic Cations, [(phen)M(CH3)]+ with Acetone: Only Platinum Promotes a Catalytic Cycle via the Enolate [(phen)Pt(OC(CH2)CH3)]+
Authors: Greis Kim , Canty Allan J. , O’Hair Richard A. J. 
Published: March 2019

Abstract
Electrospray ionisation of the ligated group 10 metal complexes [(phen)M(O2CCH3)2] (M = Ni, Pd, Pt) generates the cations [(phen)M(O2CCH3)]+, whose gas-phase chemistry was studied using multistage mass spectrometry experiments in an ion trap mass spectrometer with the combination of collision-induced dissociation (CID) and ion-molecule reactions (IMR). A new catalytic cycle has been discovered. In step 1, decarboxylation of [(phen)M(O2CCH3)]+ under CID conditions generates the organometallic cations [(phen)M(CH3)]+, which react with acetone to generate the [(phen)M(CH3)(OC(CH3)2)]+ adducts in competition with formation of the coordinated enolate for M = Pt (step 2). For M = Ni and Pd, the adducts regenerate [(phen)M(CH3)]+ upon CID. In the case of M = Pt, loss of methane is favored over loss of acetone and results in the formation of the enolate complex, [(phen)Pt(OC(CH2)CH3)]+. Upon further CID, both methane and CO loss can be observed resulting in the formation of the ketenyl and ethyl complexes [(phen)Pt(OCCH)]+ and [(phen)Pt(CH2CH3)]+ (step 3), respectively. In step 4, CID of [(phen)Pt(CH2CH3)]+ results in a beta-hydride elimination reaction to yield the hydride complex, [(phen)Pt(H)]+, which reacts with acetic acid to regenerate the acetate complex [(phen)Pt(O2CCH3)]+ and H2 in step 5. Thus, the catalytic cycle is formally closed, which corresponds to the decomposition of acetone and acetic acid into methane, CO, CO2, ethene and H2. All except the last step of the catalytic cycle are modelled using DFT calculations with optimizations of structures at the M06/SDD 6-31G(d) level of theory.
Autoregulated Resistance Training: Does Velocity-Based Training Represent the Future?
Authors: Nevin Jonpaul 
Published: March 2019

ABSTRACT
TRADITIONALLY, RESISTANCE TRAINING INTENSITY HAS BEEN BASED UPON A PERCENTAGE OF AN INDIVIDUAL'S 1RM. HOWEVER, THERE ARE NUMEROUS SHORTCOMINGS WITH THIS APPROACH, INCLUDING ITS FAILURE TO CONSIDER AN ATHLETE'S CONDITIONAL, DAY-TO-DAY TRAINING READINESS. IN ORDER TO ADDRESS THESE LIMITATIONS, THE USE OF VARIOUS PROGRESSIVE AUTO-REGULATED RESISTANCE TRAINING PROTOCOLS HAS BEEN SUGGESTED IN THE LITERATURE. RECENT ADVANCES IN THE MONITORING OF MOVEMENT VELOCITY OFFER A UNIQUE APPROACH BY WHICH TO OPTIMIZE THE USE OF AUTO-REGULATED RESISTANCE TRAINING. BY MATCHING ESTABLISHED ACUTE RESISTANCE TRAINING VARIABLES TO SPECIFIC MOVEMENT VELOCITIES THE STRENGTH AND CONDITIONING PRACTITIONER CAN OPTIMIZE RESISTANCE TRAINING INTENSITY AND OBJECTIVELY IDENTIFY THE ONSET OF NEUROMUSCULAR FATIGUE.
Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast
Authors: Yabuki Yukari , Ikeda Atsuko , Araki Misako , Kajiwara Kentaro , Mizuta Keiko , Funato Kouichi 
Published: March 2019

Abstract
Reduced ribosome biogenesis in response to environmental conditions is a key feature of cell adaptation to stress. For example, ribosomal genes are transcriptionally repressed when cells are exposed to tunicamycin, a protein glycosylation inhibitor that induces endoplasmic reticulum stress and blocks vesicular trafficking in the secretory pathway. Here, we describe a novel regulatory model, in which tunicamycin-mediated stress induces the accumulation of long-chain sphingoid bases and subsequent activation of Pkh1/2 signaling, which leads to decreased expression of ribosomal protein genes via the downstream effectors Pkc1 and Sch9. Target of rapamycin complex 1 (TORC1), an upstream activator of Sch9, is also required. This pathway links ribosome biogenesis to alterations in membrane lipid composition under tunicamycin-induced stress conditions. Our results suggest that sphingolipid/Pkh1/2-TORC1/Sch9 signaling is an important determinant for adaptation to tunicamycin-induced stress.
The efficacy of adding vitamin B12 to pegylated interferon and ribavirin treatment in Hepatitis C virus patients regarding the host and viral prognostic factors
Authors: Mokhtare Marjan , Zeidabadi Ahmad Darvishi , Bahardoust Mansour , Safari Saeid , Barati Mitra , Agah Shahram , Motavaf Mahsa 
Published: March 2019

Introduction: Hepatitis C virus (HCV) infection affects almost 180 million people around the world. Even though the development of direct acting antivirals (DAAs) has significantly improved the treatment responses to HCV infection, treatment with pegylated interferon (PegIFN) in combination with ribavirin is considered the standard of care (SOC) for chronic HCV infection treatment in countries with limited medical resources. Considering the inhibitory effect of vitamin B12 on HCV replication, we have evaluated the effect of vitamin B12 supplementation along with SOC on treatment outcomes in patients with chronic HCV infection, who were antiviral treatment-naive.
Methods: In this regard, seventy-four HCV-infected patients, naïve to antiviral therapy, were randomly assigned to receive SOC or SOC in addition to vitamin B12 (SOC + B12). Viral response was evaluated at 4, 12, 24 and 48 weeks following the initiation of viral treatment and at 24 weeks after completing the treatment. Genotyping of the interleukin 28B (IL28B) polymorphisms was also performed. Demographic characteristics, clinical findings, fibroscan results and drug adverse effects were recorded.
Results: Our findings showed that rapid viral response was not significantly different between the two groups; however, the rates of complete early viral response (cEVR) (p=0.033), end-of-treatment viral response (ETVR) (p=0.001) and sustained virologic response (SVR) (p=0.0001) were significantly higher in SOC + B12 patients compared to SOC patients. Besides, in SOC + B12 patients, those with a higher baseline viral load and carriers of IL28B CC genotype showed significantly higher rate of SVR.
Conclusion: In conclusion, the addition of vitamin B12 significantly improved the rate of SVR in HCV-infected patients, who were naïve to antiviral therapy. As this treatment regimen is safe and inexpensive, it proposes an option for improving the effectiveness of the HCV treatment with SOC, particularly in resource-limited settings.
Condiciones de posibilidad psicosociales de una estudiante de psicología con enfermedad motora de origen cerebral
Authors: Campos Sanchez Marcela , Pedraza Cardozo Alba Paola 
Published: March 2019

La investigación se llevó a cabo en el Programa de Psicología de la Corporación Universitaria Minuto de Dios – UNIMINUTO – Sede Principal. Tuvo como objetivo comprender las condiciones de posibilidad psicosociales que estuvieron presentes en el desarrollo del proceso educativo de una estudiante de psicología con enfermedad motora de origen cerebral, tipo atetósica. En esta investigación la estudiante cumplió doble rol al ser el sujeto del estudio de caso y asistente de investigación. La metodología de la investigación contempló la revisión de investigaciones y sistematizaciones de casos similares, la reconstrucción autobiográfica de la experiencia educativa en educación superior, y la realización de entrevistas a los actores significativos de la experiencia. A partir del análisis de las prácticas discursivas desde Foucault se encontraron tres condiciones de posibilidad para desarrollar procesos para la educación para la diversidad: (a) disolver la correlación entre parálisis cerebral y discapacidad cognitiva, (b) cuestionar el saber-hacer especializado sobre la discapacidad, y (c) superar el miedo a relacionarse con los cuerpos diversos.
Estado de la cuestión de los centros y programas de escritura de Latinoamérica
Authors: Molina-Natera Violeta , López-Gil Karen Shirley 
Published: March 2019

Esta investigación buscaba identificar las teorías, prácticas y procesos de gestión de los centros y programas de escritura en universidades de América Latina. Para ello, se propuso un estudio exploratorio que tuvo como principal instrumento un cuestionario en línea. Participaron en la investigación 23 directores de centros y programas de escritura de la región. Los resultados evidencian una variedad de programas muy jóvenes en su conformación. La escritura empieza a incluirse en las agendas programáticas de las universidades latinoamericanas, teniendo en cuenta el respaldo institucional conferido a estas iniciativas en los últimos 10 años. Respecto a los fundamentos teóricos, se encontró una diversidad de enfoques y posturas teóricas que configuran estos centros y programas de forma distinta a sus antecesores en Norteamérica. Los programas incorporan prácticas que tienen que ver, en su mayoría, con el acompañamiento individual a través de tutorías o con el trabajo colaborativo entre docentes de lengua y docentes de otras disciplinas. La gestión administrativa plantea un desafío especial en cuanto a la medición del impacto de los programas. Los directores asumen una serie de funciones que requieren de una capacitación integral en tareas administrativas, con la cual no se cuenta aún en la región. Estos resultados evidencian la necesidad de fortalecer los procesos de gestión de estas iniciativas y la pertinencia de consolidar un campo propio de investigación.