bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study of patients' satisfaction in different levels of hospitals in Beijing: Why do patients prefer high-level hospitals?
Authors: Cui Chengsen , Zuo Xu , Wang Yujia , Song Haiyan , Shi Jingyu , Meng Kai 
Published: September 2019

Abstract
Background: In order to promote the vertical flow and integration of medical resources, Beijing built medical alliances since 2012, but this practice did not change the disordered state of medical treatment. Patients are still willing to go to high-level hospitals for medical treatment. What causes patients to prefer high-level hospitals? Through previous research, patients' choice of medical treatment was affected by patients' satisfaction. Therefore, we compared the patients' satisfaction in different level hospitals under the background of the medical resource integration. Methods: This study conducted a 48-person interview and a questionnaire survey among 1,250 patients who were treated in 18 medical alliances in Beijing from October to December 2016. The patients’ satisfaction was the main outcome, descriptive analysis, a chi-square test, a nonparametric test and binary logistic regression analysis were used. The level of statistical significance was set at p<0.05. Results: The total satisfaction score of the medical alliances is 3.375, and the satisfaction score of core hospitals and cooperative hospitals is 2.77 and 3.07 respectively. The overall patient satisfaction rate is 44.62%, among which the satisfaction rate of core hospitals is 34.34% and that of the cooperative hospitals is 50.43%. The type of hospital and understanding of medical alliance policy are the influencing factors of the patients’ satisfaction with the medical alliance. Conclusions: Patients are more satisfied with the core hospitals. However, because core hospitals have obtained the most subsidies with limited financial compensation, the gap between core hospitals and cooperative hospitals is growing. The phenomenon of disorderly medical treatment in China seems more intense. Therefore, it is necessary to explore the establishment of closed medical alliances so that provide integrated medical services for patients.
Clinic facilities and staff communication skills influence antenatal care attendance in Saudi Arabia
Authors: Alanazy Wdad , Brown Amy 
Published: September 2019

Abstract
Background The World Health Organisation recommends women have at least 4 antenatal care visits (ANC) during a low risk pregnancy. However, in Saudi Arabia, many mothers miss these appointments placing their health and that of their baby at risk. Limited research exploring why this is happening usually focuses on low maternal education or personal barriers such as lack of transport. The aim of the current research was therefore to understand what factors at the individual and healthcare systems level were associated with missing antenatal care in Saudi Arabia.Methods Pregnant women in their third trimester completed a questionnaire examining their care attendance alongside barriers to attending care. These included maternal demographic background, health literacy, personal barriers, health care system factors and staff communication).Results Over half of women had missed at least one appointment and a third had delayed their care. Mothers who had missed appointments blamed health care system factors such as poor clinic facilities and waiting times. Attending care was not associated with maternal education or literacy. However perceptions of staff communication, consistency and care were lower amongst those who had missed at least one appointment.Conclusions Although in previous research health professionals believe it is maternal education that leads to poor attendance, in our sample at least, it is in fact perceptions of staff communication that affect attendance. Making changes at the health care level e.g. through adapting clinic times and investing in staff training may increase antenatal care attendance in Saudi Arabia.
The impact of applying 5S management method on patient satisfaction in healthcare centers' services
Authors: Shahali Shadab , Khajehasani Massomeh , Torabipoor Amin , AhmadiAngali Kambiz 
Published: September 2019

Abstract
Background: Improving service quality and increasing clients' satisfaction is the most important aim of the health centers. This study aimed to investigate the effect of implementing the 5S management approach on the service quality provided at community health centers.Methods: This is a quasi-experimental study done with the participation of 220 pregnant women at a health center in Ahvaz in 2018. The quality gap and weaknesses were measured before 5S implementation by using adornment system (5S) checklist and SERVQUAL questionnaire. Interventions were designed and implemented with regard to the system weaknesses and the next evaluation was carried out 2 months after intervention.Results: Based on the findings of this study, the 5S score was 2.4 before the 5S implementation and 4.2 after the intervention. The mean scores of health service quality provided in community health centers significantly differed before and after the 5S implementation (P <0.0001).Conclusions: Implementation of 5S can improve the work environment adornment and the satisfaction of health centers' patients. Therefore, it is advised to use techniques to increase the quality of health centers’ services.
Synergistic therapeutic effects of metformin at a clinically relevant dosage in combination with chemotherapy via the AKT/mTOR pathway on ovarian cancer
Authors: WEN KUO-CHANG , Sung Pi-Lin , Wu Alexander T.H. , Chou Ping-Chieh , Lin Jun-Hung , Wang Peng-Hui , Huang Chi-Ying F. , Yeung Sai-Ching J. , Lee Mong-Hong 
Published: September 2019

Abstract
Background Ovarian cancer is the leading cause of cancer-related death among women. Metformin has antitumor effects in many cancer models. However, many studies have shown that metformin has cytotoxic activity at higher concentrations than those used for diabetic patients; this effect may be derived from high concentrations directly inducing the death of tumor cells. The synergism of metformin at clinically relevant dosages and chemotherapy in ovarian cancer remains unclear.Methods We applied two clinical databases to survey metformin use and ovarian cancer survival rate. The Cancer Genome Atlas dataset, an L1000 microarray with Gene Set Enrichment Analysis (GSEA) analysis, western blot analysis and an animal model were used to study the activity of the AKT/mTOR pathway in response to the synergistic effects of metformin and chemotherapy.Results We found that ovarian cancer patients treated with metformin had significantly longer overall survival than did patients treated without metformin. The gene profile induced by metformin in ovarian cancer predominantly involved the AKT/mTOR pathway. Micromolar concentrations of metformin alone and in combination with chemotherapy also reduced cell viability via the AKT/mTOR pathway in vitro and in vivo . Both neoadjuvant and concurrent therapy protocols showed good synergistic effects.Conclusions This study shows that metformin at clinically relevant dosages is efficacious in treating ovarian cancer, and the results can be used to guide clinical trials.
Altered staining patterns and expression level of Engrailed-2 in Benign prostatic hyperplasia and Prostate Cancer predict Prostatic disease progression
Authors: Li Qi , Shi Yibo , Sa Rigai , Hao Jun , Hu Jinhao , Xiao Mulun , Wang Chaoliang , Yan Liang , Qiao Baoping , Chen Guoxun 
Published: September 2019

Abstract
Background: Prostate cancer (PC) as a kind of malignant tumor, causes the most death of cancer among males. Successful curing of PC greatly relies on its diagnose in the early stage. Engrailed-2 (EN2), which has been confirmed being existed in the high level in the urine of PC patients, has not been reported as a histochemical diagnostic biomarker of PC. In this study, we analyzed the EN2 expression level and staining patterns in PC and benign prostatic hyperplasia (BPH) samples for seeing the change of EN2 in PC early stage. Methods: EN2 monoclonal antibody was generated and the specificity of this antibody was validated with different maneuvers. Endogenic and exogenous of EN2 in three PC cell lines (LNCap, PC3, and DU145) was detected by immunofluorescence. The expression level and staining patterns of EN2 in 25 of PC and 25 of BPH tissues were detected by immunohistochemistry. RT-PCR was done for further conforming whether EN2 is overexpressed in PC and BPH tissues. Finally, a relationship of EN2 expression and PC occurrence was obtained by case analysis of PC. Results: The results of WB and immunofluorescence showed the monoclonal antibody of EN2 we made could specifically bind endogenic and ectogenic EN2 protein in three different PC cell lines. Results of immunofluorescence showed the endogenic EN2 was generally expressed in the cytoplasm and ectogenic EN2 has mostly existed in the nucleus. Immunohistochemical staining of EN2 in PC was extremely higher than in BPH confirmed by RT-PCR. The staining areas were mostly nucleus and cytoplasm in BPH tissues but cytomembrane in PC tissues. The expression level of EN2 was positively correlated with the PC clinical stage. Conclusion: The EN2 monoclonal antibody we made could distinguish BPH and PC by immunohistochemistry. The expression level and tissue distribution pattern of EN2 can help with the determination of PC’s progression.
Is it possible to increase the amount of physical activity in patients isolated due to stem cell transplantation?
Authors: Vejby Sölvi 
Published: September 2019

Abstract
Abstract Purpose: To investigate if physical activity (PA) support could increase PA and health-related quality of life (HRQoL) in patients isolated after haematological stem cell transplantation, compared with standard care. Methods: A prospective historical control group design was used. Patients were sequentially included in a standard care group (SCG, n=22) or a physical activity support group (PASG, n=21). PASG patients received PA support at a pre-transplantation consultation, daily during admission, and at follow-up 14 days post-discharge. All participants undertook a 6-minute walking test (6MWT) at the beginning and end of their hospital stay. HRQoL was evaluated using the Functional Assessment of Cancer Therapy – Anaemia scale. Patients reported all PA, including sitting, throughout their hospital stay. Metabolic Equivalents of Task (METs) were calculated. Results: PASG patients spent more time sitting and doing various activities, and less in bed, than SCG patients (p=0.03–0.06). They had more calculated METs for total PA out of bed (p=0.02) and time spent sitting (p=0.05). PASG patients walked further in the 6MWT than SCG patients at baseline (p=0.02) and at discharge, but not significantly. There were no statistically significant differences in HRQoL, but PASG patients had clinically important less fatigue at discharge and clinically important better HRQoL 6 months post-discharge. Conclusions: Providing stem cell patients, pre-transplantation, with individual care plans for structured PA support during the hospital stay might increase PA and have a clinically important impact on HRQoL. Larger studies are needed to evaluate the effects of PA support on medical outcome and length of hospital stay.
Unilateral Inferior Oblique Anterior Transposition for Markedly Asymmetric Dissociated Vertical Deviation with Unilateral Inferior Oblique Over-action
Authors: Wu Shuang-Qing , Xu Qi-Bin , Sheng Wen-Yan , Zhu Li-Wei 
Published: September 2019

Abstract
Background: To evaluate the results of unilateral inferior oblique anterior transposition (IOAT) for markedly asymmetric dissociated vertical deviation (DVD) combined with inferior oblique over-action (IOOA).
Methods ： Retrospective chart review of the records of all patients with asymmetric DVD combined with unilateral IOOA in the non-dominant eye who received unilateral IOAT on the non-dominant eye. No other muscles were operated on simultaneously. The amount of DVD and IOOA were measured before and after the operation and statistically analysed.
Results: Seventeen patients were included. The mean age at surgery was 23.5 ± 8.4 (range 12 – 38) years old. The mean postoperative follow-up period was 15.7 ± 7.2 (range 6–32) months. The primary position DVD was 19.6 ± 5.4 (range 14–36) PD preoperatively and decreased significantly to 2.9 ± 2.0 (range 0–8) PD postoperatively ( P < 0.01 ). Preoperatively, there were 2, 7, and 8 patients with +1, +2, and +3 IOOA, respectively, and these were reduced from 2.4 ± 0.7 to 0.3 ± 0.4 postoperatively ( P < 0.01). None of the patients were complicated obvious hypotropia, anti-elevation syndrome or IOOA in the contralateral eye.
Conclusions: Unilateral IOAT was recommended in patients with asymmetric DVD coexists with unilateral IOOA.
Interest in Islam and Cross Religions
Authors: Bin Armia Muhammad Syauqi 
Published: September 2019

The Islamic principle encourages people to be alert for society. To achieve the objective of sharia, Muslim has been provided the clear path to collaborate with the creatures fairly. The injustice financial practice one of the aspects that Islamic principles emphasise to not involve. On top of this, the usury (Riba) where someone charges the excess for the loan unfairly.
The interest practice has been a critical topic throughout the time. Due to the unfair practice, the major religions and civilisations cursed this practice as general. Nevertheless, in practical situations, there were numbers of approaches for each religion and civilisation. Plato with among ancient philosopher criticized this and argued this is a media to squeeze poor people. In Judaism, the interest is prohibited among Jews, while in the Hinduism allowed otherwise in a lower caste in the society. In Christianity, priests in the medieval banned this practice, but it has been diluted in the 6th century due to the sovereign pressure. Islam sprightly prohibited the interest despite the diversity of its models, the value, the grade and to whom it will be exercised.
This article emphasises on Islamic finance point of view towards the cross religions and civilisation. Utilised the library/literature-based research, the author delivers the main ideas in the comparative approaches of the interest issues.
Experimento didático: uma pesquisa para investigar mudanças cognitivas no processo de modelagem matemática
Authors: Garcia Vera Clotilde , Menna Barreto Marina 
Published: September 2019

Este artigo relata uma pesquisa seguindo a metodologia do “experimento didático”1, desenvolvida com estudantes adolescentes, da 2ª série do ensino médio, confrontados com um conjunto de atividades cujo centro é o processo de modelagem de um fenômeno ligado ao tema da sexualidade e às questões da gravidez precoce: a absorção e eliminação de um anticoncepcional oral. O objetivo foi tentar compreender as mudanças que ocorrem nos esquemas dos estudantes quando utilizam matemática conhecida para interpretar e resolver problemas reais. Concluímos que uma proposta didática que vincule o interesse pelo real com a matemática pode desenvolver mudanças cognitivas importantes, reorganizando esquemas insuficientes, atribuindo sentido à matemática e melhorando a percepção e a interpretação da realidade. O ensino usual não abre caminhos para a aplicação da matemática nas outras ciências, pois tem seus fundamentos em condições aparentemente absolutas e em concepções estáticas.
Workplace Mindfulness in Accounting Practice: Issues, Opportunities, and Challenges
Authors: Chang Yu-Tzu , Stone Dan N. 
Published: September 2019

SYNOPSIS
Research suggests that individual, secular mindfulness can improve work outcomes, including reducing stress and increasing attention, wellness, and job performance. This paper discusses the construct and efficacy of mindfulness and explores opportunities for and challenges to integrating workplace mindfulness in professional accounting. Evidence from websites suggests that most large accounting firms promote workplace mindfulness to their clients and that some (e.g., EY and PWC) promote its practice among their accounting professionals. While a review of literature indicates support for some claimed benefits, workplace mindfulness is no panacea. Challenges to workplace mindfulness include the unwillingness of some accounting professionals to practice mindfulness and that some claimed benefits, e.g., improved leadership and teamwork, are not well-supported by research. The paper concludes by proposing a set of workplace mindfulness issues and practice opportunities and discussing impediments to and the limits of mindfulness in professional accounting.
JEL Classifications: M40; M41; M42.
CEO Behavioral Integrity, Auditor Responses, and Firm Outcomes
Authors: Dikolli Shane S. , Keusch Thomas , Mayew William J. , Steffen Thomas D. 
Published: September 2019

ABSTRACT
We investigate the audit fee response to CEO behavioral integrity (BI). BI refers to the perceived congruence between an individual's words and deeds (Simons 2002). Because low word-deed congruence should result in more explanations when communicating, we use variation in explanations beyond firm fundamentals and CEO-specific characteristics in more than 30,000 shareholder letters to serve as a linguistic-based proxy for CEO BI. We find that audit fees increase as BI decreases, but BI is not associated with financial misstatement or litigation. These findings are potentially consistent with auditors undertaking additional work in response to low BI, which, in turn, mitigates the risk of restatements and lawsuits. The likelihood of option backdating increases as BI decreases, consistent with the contention that auditors lacked incentives to prevent backdating. Finally, BI is increasing in future performance, which suggests that CEOs partially underpin the returns to high-integrity corporate cultures.
JEL Classifications: J24; L25; M14; M41; M42.
Data Availability: Proprietary data from KRW International cannot be shared because of the terms of a confidentiality agreement. All other data are available from the public sources cited in the text.
East, West, Home's Best: Do Local CEOs Behave Less Myopically?
Authors: Lai Shufang , Li Zengquan , Yang Yong George 
Published: September 2019

ABSTRACT
We test whether CEOs working near their childhood homes are less likely than nonlocal CEOs to make myopic decisions. Place attachment theories suggest that people develop mutual caretaking relationships with their birthplaces. Also, executive labor markets face less information asymmetry about local CEOs, resulting in lower pressure on local CEOs for quick profits. Consistent with the prediction, we find that local CEOs are less likely to cut R&D expenditures for beating analyst forecasts or avoiding earnings decreases. In their last year of office, local CEOs are significantly less likely to cut R&D than nonlocal CEOs. The CEO locality effect is stronger when more local business interests are embedded in the firm and when the residents of the CEO's birth state have stronger local social bonds. Local CEOs' longer horizons are consistently manifested in their other decisions, such as paying more state tax and being more socially responsible in business operation.
JEL Classifications: G10; G23; M40.
Deflasi Semantis dalam Pertukaran antara Bahasa Inggris dan Bahasa Indonesia
Authors: Adipurwawidjana Ari J. 
Published: September 2019

Penggunaan unsur-unsur bahasa Inggris dalam wacana Indonesia kontemporer semakin menjadi lazim dan meresap dalam berbagai konteks mulai dari percakapan sehari-hari, forum akademik, hingga media massa baik dalam bentuk ujaran lisan maupun teks tertulis. Perjumpaan antara bahasa Inggris dan bahasa Indonesia sama sekali bukan fenomena baru. Tiga periode pertukaran interlinguistik antara kedua bahasa dapat diidentifikasi sebelum periode yang sedang berlangsung kini, mulai dari (1) pertukaran tidak langsung melalui bahasa lain, (2) pertukaran langsung terdokumentasi sejak awal abad ke-19 yang bertepatan dengan kehadiran Imperium Britania di Asia Tenggara yang memfasilitasi dimasukannya sejumlah besar kata-kata Melayu ke dalam kosakata bahasa Inggris, dan (3) periode pasca-Perang Dunia II saat Indonesia menjadi lebih terlibat dalam ekonomi global yang berkontribusi pada penyebaran praktik budaya (Adipurwawidjana, 2013). Namun, walaupun dalam pertukaran semacam itu pergeseran dan modifikasi pada berbagai tingkat linguistik tidak dapat dihindari, arus lintas budaya yang melimpah saat ini tampaknya tidak memberikan kesempatan bagi unsur-unsur bahasa yang dipinjam untuk beradaptasi dengan struktur bahasa Indonesia sebagai bahasa peminjam, yang mengakibatkan penggunaan nahasa Inggris yang sepotong-sepotong dan terfragmentasi dalam penggunaan bahasa Indonesia secara umum. Hal ini merupakan gejala yang disebut Halpern (2001, 2008) sebagai "deflasi semantik," sebuah gejalan yang mengurangi nilai dan bobot semantik karena penggunaan bahasa di tingkat permukaan belaka tidak memberikan ruang yang cukup untuk penyerapannya. Melihat ujaran sehari-hari dan teks-teks yang hadir di ruang publik, tulisan ini akan menunjukkan terjadinya deflasi semantik atas kata dan frasa yang dipinjam bahasa Inggris dalam wacana Indonesia kontemporer, termasuk degradasi elemen eufemistik dan disfemistik, penggunaan yang tidak idiomatis, dan formasi kata non-standar.
The Method of Predicting the Extent of Changes in the Performance Characteristics of Residential Buildings
Authors: Nowogońska B. 
Published: September 2019

AbstractAccordingly to recommendations set out by standards, degradation curves which will serve as a tool facilitating decision-making regarding renovation works ought to be developed. The article presents the proposal of a model for predicting the aging of a residential building. The proposed PRRD (Prediction of Reliability According to Rayleigh Distribution) model determines the performance characteristics of a building over the full period of its use. PRRD accounts for the life spans of individual building components. Additionally introduced in the model were supplements accounting for the intensity of changes in the building and its surroundings. The developed method of the non-linear degradation process of a building accounts for the role and weights of individual building components as well as the intensity of significant factors influencing the aging process. The presented methodology of the description of changes in the performance characteristics over the course of using a building will be a diagnostic process of predicting the technical state of a building. The proposed predictions can serve as the basis for making the right strategic decisions when planning renovation works in residential buildings.
Original Model for Estimating the Whole Life Costs of Buildings and its Verification
Authors: Plebankiewicz E. , Zima K. , Wieczorek D. 
Published: September 2019

Abstract
The model for estimating the whole life costs of the building life cycle that allows the quantification of the risk addition lets the investor to compare buildings at the initial stage of planning a construction project in terms of the following economic criteria: life cycle costs (LCC), whole life costs (WLC), life cycle equivalent annual costs (LCEAC) and cost addition for risk (ΔRLCC). The subsequent stages of the model development have been described in numerous publications of the authors, while the aim of this paper is to check the accuracy of the model in the case of changing the parameters that may affect the results of calculations. The scope of the study includes: comparison of the results generated by the model with the solutions obtained in the life cycle net present value method (LCNPV) for time and financial input data, not burdened with the risk effect; the analysis of the variability of results due to changes in input data; analysis of the variability of results as a consequence of changing the sets of membership functions for input data and methods for defuzzification the result.