bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Church for the Polish People: On the Contest for the Parochial Church in the Warsaw District of Praga
Authors: Nowicki Jan 
Published: August 2019

The present article discusses the architectural contest for the design of the Praga parish church in Warsaw, announced in 1886. The author aims to establish whether this event had any significant impact on the development of Polish architecture and its theoretical principles. He reviews the reasons for its importance and attempts to establish whether it constitutes suitable material for more thorough studies, the results of which would merit a prominent place in the historiography of 19th century architecture in Poland. The critical interpretation presented in this article is based primarily on texts published in Przegląd Techniczny, which discuss the successive stages of the contest, as well as selected press articles and essays written in direct connection to this enterprise. The author analyses texts by Karol Matuszewski, Franciszek Ksawery Martynowski, Władysław Łuszczkiewicz and Józef Pius Dziekoński, which are crucial for understanding the complex nature of the issue of the contest. The analysis leads to the conclusion that it was not the ultimate form of the church, but rather the combination of emotions, hopes, interests and controversies provoked by the announcement of the contest and the phrasing of its requirements that determined the crucial role of this event in the history of Polish architecture in the latter part of the 19th century.
Rubble Warsaw, 1945–1946: Urban Landscaping and Architectural Remains
Authors: Przywara Adam 
Published: August 2019

This paper is a contribution to the contemporary discussions around architectural materialities and the history of the immediate post-war period in the urban areas of Europe. The opening paragraphs include references to the artistic action The Cut which took place in 2015, exposed the anthropogenic strata in Warsaw’s landscape and acknowledged the continuous material existence of the city’s history within its soil. Focusing on rubble, debris and post-war architectural waste, the author presents the theoretical approach by referring to a broad shift in the humanities towards approaches oriented towards objects and particular materialities. The subsequent historical narrative centres on the problems of rubble clearing and utilisation in the early reconstruction period of Warsaw. It shows the views and operations aimed at the removal of the mass of rubble proposed by the architects from the Bureau for the Capital City Reconstruction (BOS) and the inhabitants returning to the ruined city in 1945. Mobilising both narratives, the paper presents problems and discussions related to rubble utilisation and removal. Referring to Maciej Nowicki’s unrealised design for Warsaw’s city centre and contrasting it with the oral testimonies of the city’s inhabitants, the article reveals the struggles and discussions that raged during that early stage of city reconstruction. Finally, through the use of various sources from geological mapping to archival materials, the paper aims to locate, describe and document the rubble landscapes located around the city of Warsaw. In the conclusion the author points out how the subject could be expanded and how rubble relates to contemporary discourses in the humanities.
Modernity and Compromise: The Church of St. Michael the Archangel in Warsaw and its Designer Władysław Pieńkowski
Authors: Głowacki Wojciech M. 
Published: August 2019

Despite the considerable influence he exerted on post-war church architecture in Poland, the designer Władysław Pieńkowski (1907–1991) is today an altogether forgotten figure. The current paper outlines his biography and his early oeuvre; this is because his experience in designing office blocks and industrial plants gained while working under the supervision of the most outstanding Polish architects of the mid-20th century, was to be of key importance to his later, independent designs for ecclesiastical buildings. The paper focuses on a particularly important work, one which in many ways constitutes a breakthrough in the architect’s career, namely the church of St. Michael the Archangel in the Mokotów district of Warsaw. This was the first entirely new church to be erected in the capital of Poland after the year 1945. Its construction depended on the dynamic changes in the balance of political forces. The church could be built owing to the support of the PAX Association circle, including the direct involvement of Bolesław Piasecki. In spite of their patronage, however, construction works were repeatedly halted and extended over several years, and the architectural design had to be reworked. The paper contains an analysis of three fundamental designs for the church, now held in the St. Michael the Archangel parish archive and in the architect’s records preserved by his heirs. The first design dates from the period of 1948/9–1951, the subsequent one from the year 1954, and the final one from 1956–1961. The evolution of the design moved from the initial continuation of forms typical of the pre-war Modernised Revivalism, through a peculiar reference to Socialist Realism, to rigorous Modernism. The church of St. Michael the Archangel became Pieńkowski’s testing ground; there, he tried out several solutions which he would consistently utilise in the subsequent years of his career, e.g. the large-scale application of prefabricated elements in both the construction and the decoration of the edifice. The construction of this church was concurrent with important events of a political (the Thaw) and religious nature (the Second Vatican Council). Tracing the history of the design for the Warsaw church and clarifying its connections with contemporaneous church architecture in Poland and in Western Europe made it possible to present the key problems faced by the Polish designers of ecclesiastical architecture in the first decades of the People’s Republic of Poland.
Aqueous two-phase extraction of semiconducting single-wall carbon nanotubes with isomaltodextrin and thin-film transistor applications
Authors: Omachi Haruka , Komuro Tomohiko , Matsumoto Kaisei , Nakajima Minako , Watanabe Hikaru , Hirotani Jun , Ohno Yutaka , Shinohara Hisanori 
Published: August 2019

Abstract
Semiconducting single-wall carbon nanotubes (s-SWCNTs) are promising materials with potential applications in thin-film transistors (TFTs). However, separation techniques are required to obtain highly enriched s-SWCNTs since conventional as-grown SWCNTs are a mixture of 70% semiconducting and 30% metallic SWCNTs. Here, we developed a rapid single-step aqueous two-phase extraction of high-purity s-SWCNTs using isomaltodextrin, which is a cost-effective polysaccharide that contains a large amount of α-1,6-glucosidic linkages. We also succeeded in fabricating high-density uniform films directly from the high-purity s-SWCNT extract. Fabricated TFTs exhibited an excellent on/off ratio, carrier mobility, and on-current density.
Evaluation of CHROMagar ESBL and Double Disk Synergy Test (DDST) for Screening of Extended Spectrum Beta-lactamase Producing Uropathogens in South-South Nigeria
Authors: Uyanga F. Z. , Ekundayo E. O. , Nwankwo E. O. , Inimfon A. I. 
Published: August 2019

Background/Purpose: The aim of this study was to evaluate the effectiveness of CHROMagar ESBL in comparison with Double Disc Synergy Test (DDST) for the detection of ESBL producing uropathogens.
Methods: Six hundred and sixty urine samples were collected from pregnant women attending antenatal at General hospital Ikot Ekpene, Eket and Oron. Two hundred and fifty eight isolates were obtained while two hundred and thirty one isolates were ESBL producers. Microbact 24E(Oxoid, UK) was used in the identification of bacterial isolates, antibiotic susceptibility test was done using Kirby-Bauer disk diffusion method following CLSI guidelines using commercially available disc (Oxoid Ltd). Double disk synergy test was carried out on the isolates and inoculation was done using CHROMagar ESBL (France).
Results: The prevalence of ESBL 35% was recorded. The sensitivity and specificity of DDST was 88% and 89%, respectively. CHROMagar showed an increase in sensitivity and specificity at 48 h with 98% and 99.0%, respectively. 80% of the ESBL producing isolates were multi drugs resistant. The predominant bacterial pathogens were Enterobacter cloacae (23%), Proteus mirabilis (14%) and Acinetobacter baumanii (13.4%).The ESBL producing isolates showed maximum resistance against Ceftazidime (90%), Cefotaxime (91%), Azetronam (95%), Amikacin (68.2%) followed by ofloxacin (70%) while maximum sensitivity was seen for imipenem (90%) and Augumentin (80%). The study demonstrated that CHROMagar was superior and more sensitive than DDST.
Conclusion: CHROMagar ESBL seems to be the most reliable method among phenotypic methods for detection of ESBL in the absence of PCR.
Clustering in the Golgi apparatus governs sorting and function of GPI‐APs in polarized epithelial cells
Authors: Lebreton Stéphanie , Paladino Simona , Zurzolo Chiara 
Published: August 2019

Glycosylphosphatidylinositol‐anchored proteins (GPI‐APs) are lipid APs attached to the extracellular leaflet of the plasma membrane (PM) via a glycolipid anchor. GPI‐APs are commonly associated with cholesterol‐ and sphingolipid‐enriched membrane microdomains. These microdomains help regulating various biological activities, by segregating different proteins and lipids in (nanoscale) membrane compartments. In fibroblasts, GPI‐APs form actin‐ and cholesterol‐dependent nanoclusters directly at the PM. In contrast, in polarized epithelial cells GPI‐APs cluster in the Golgi apparatus, the major protein‐sorting hub for the secretory pathway. Golgi clustering is required for the selective sorting of GPI‐APs to the apical PM domain, but also regulates their organization and biological activities at the cell surface. In this review, we discuss recent advances in our understanding of the mechanism of GPI‐AP sorting to the apical membrane. We focus on the roles of the protein moiety and lipids in the regulation of the clustering of GPI‐APs in the Golgi apparatus.
Analysing openly recorded preinterview deliberations to detect deceit in collective interviews
Authors: Vrij Aldert , Jupe Louise Marie , Leal Sharon , Vernham Zarah , Nahari Galit 
Published: August 2019

SummarySham marriages occur frequently, and to detect them, partners are sometimes interviewed together. We examined an innovative method to detect deceit in such interviews. Fifty‐three pairs of interviewees, either friends (truth tellers) or pretended to be friends (liars), were interviewed about their friendship. Just before the interview, they received the questions that would be asked in the interview and were invited to prepare the answers. We told them that these preinterview deliberations would be recorded. Based on the transcripts, we analysed cues to truthfulness (cues expected to be expressed more by truth tellers) and cues to deceit (cues expected to be expressed more by liars). Truth tellers and liars differed from each other, particularly regarding expressing cues to truthfulness. Preinterview deliberations that are recorded with awareness of the interviewees can be used for lie detection purposes. We discuss further venues in this new line of research.
A Chemical Photo‐Oxidation of 5‐Methyl Cytidines
Authors: Jin Xiao‐Yang , Wang Rui‐Li , Xie Li‐Jun , Kong De‐Long , Liu Li , Cheng Liang 
Published: August 2019

AbstractA new approach for the oxidation of 5‐methyl cytidine modification in nucleic acids to 5‐formyl cytidine is reported. This method displays excellent chemo‐/bio‐ selectivity, from which the methyl group in cytidine nucleosides could be selectively oxidized to biologically important formyl functionality without interfering with other cellular biomolecules.magnified image
Surgical Cleavage of Unstrained C(sp3)−C(sp3) Bonds in General Alcohols for Heteroaryl C−H Alkylation and Acylation
Authors: Wang Yaxin , Yang Le , Liu Shuai , Huang Lixia , Liu Zhong‐Quan 
Published: August 2019

AbstractWe reported herein a predictable and surgical cleavage of carbon‐carbon bond in alcohols. A wide range of 1°, 2° and 3° alcohols including sugars and steroids without ring strain or steric hindrance were all compatible with this system. Also it offered a green and practical strategy for generation of alkyl/acyl radicals using alcohols as the sources. Besides, the features of visible‐light‐initiation, catalyst and metal free, excellent selectivity and mild conditions make it valuable and attractive.magnified image
Therapeutic Targeting of MZF1‐AS1/PARP1/E2F1 Axis Inhibits Proline Synthesis and Neuroblastoma Progression
Authors: Fang Erhu , Wang Xiaojing , Yang Feng , Hu Anpei , Wang Jianqun , Li Dan , Song Huajie , Hong Mei , Guo Yanhua , Liu Yang , Li Hongjun , Huang Kai , Zheng Liduan , Tong Qiangsong 
Published: August 2019

AbstractProline synthesis plays an important role in the metabolic reprogramming that contributes to tumor progression. However, the mechanisms regulating expression of proline synthetic genes in neuroblastoma (NB) remain elusive. Herein, through integrative screening of a public dataset and amino acid profiling analysis, myeloid zinc finger 1 (MZF1) and MZF1 antisense RNA 1 (MZF1‐AS1) are identified as transcriptional regulators of proline synthesis and NB progression. Mechanistically, transcription factor MZF1 promotes the expression of aldehyde dehydrogenase 18 family member A1 and pyrroline‐5‐carboxylate reductase 1, while proline facilitates the aggressiveness of NB cells. In addition, MZF1‐AS1 binds poly(ADP‐ribose) polymerase 1 (PARP1) to facilitate its interaction with E2F transcription factor 1 (E2F1), resulting in transactivation of E2F1 and upregulation of MZF1 and other oncogenic genes associated with tumor progression. Administration of a small peptide blocking MZF1‐AS1‐PARP1 interaction or lentivirus‐mediated short hairpin RNA targeting MZF1‐AS1 suppresses the proline synthesis, tumorigenesis, and aggressiveness of NB cells. In clinical NB cases, high expression of MZF1‐AS1, PARP1, E2F1, or MZF1 is associated with poor survival of patients. These results indicate that therapeutic targeting of MZF1‐AS1/PARP1/E2F1 axis inhibits proline synthesis and NB progression.
HIST1H1E heterozygous protein‐truncating variants cause a recognizable syndrome with intellectual disability and distinctive facial gestalt: A study to clarify the HIST1H1E syndrome phenotype in 30 individuals
Authors: Burkardt Deepika D'Cunha , Zachariou Anna , Loveday Chey , Allen Clare L. , Amor David J. , Ardissone Anna , Banka Siddharth , Bourgois Alexia , Coubes Christine , Cytrynbaum Cheryl , Faivre Laurence , Marion Gerard , Horton Rachel , Kotzot Dieter , Lay‐Son Guillermo , Lees Melissa , Low Karen , Luk Ho‐Ming , Mark Paul , McConkie‐Rosell Allyn , McDonald Marie , Pappas John , Phillipe Christophe , Shears Deborah , Skotko Brian , Stewart Fiona , Stewart Helen , Temple I Karen. , Mau‐Them Frederic T. , Verdugo Ricardo A. , Weksberg Rosanna , Zarate Yuri A. , Graham John M. , Tatton‐Brown Katrina 
Published: August 2019

AbstractHistone Gene Cluster 1 Member E, HIST1H1E, encodes Histone H1.4, is one of a family of epigenetic regulator genes, acts as a linker histone protein, and is responsible for higher order chromatin structure. HIST1H1E syndrome (also known as Rahman syndrome, OMIM #617537) is a recently described intellectual disability (ID) syndrome. Since the initial description of five unrelated individuals with three different heterozygous protein‐truncating variants (PTVs) in the HIST1H1E gene in 2017, we have recruited 30 patients, all with HIST1H1E PTVs that result in the same shift in frame and that cluster to a 94‐base pair region in the HIST1H1E carboxy terminal domain. The identification of 30 patients with HIST1H1E variants has allowed the clarification of the HIST1H1E syndrome phenotype. Major findings include an ID and a recognizable facial appearance. ID was reported in all patients and is most frequently of moderate severity. The facial gestalt consists of a high frontal hairline and full lower cheeks in early childhood and, in later childhood and adulthood, affected individuals have a strikingly high frontal hairline, frontal bossing, and deep‐set eyes. Other associated clinical features include hypothyroidism, abnormal dentition, behavioral issues, cryptorchidism, skeletal anomalies, and cardiac anomalies. Brain magnetic resonance imaging (MRI) is frequently abnormal with a slender corpus callosum a frequent finding.
Coffin–Lowry syndrome in Chinese
Authors: Fung Jasmine L. F. , Rethanavelu Kavitha , Luk Ho‐ming , Ho Matthew S. P. , Lo Ivan F. M. , Chung Brian H. Y. 
Published: August 2019

AbstractCoffin–Lowry syndrome (CLS) is a well‐described syndrome characterized by intellectual disability, growth retardation, recognizable dysmorphic features, and skeletal changes. It is an X‐linked syndrome where males are more severely affected and females have high variability in clinical presentations. This case series reports nine molecularly confirmed Chinese CLS patients from six unrelated families (three with familial variants and three with de novo variants). There is a wide genotypic spectrum with five novel variants in RPS6KA3 gene. Clinical phenotype and facial features of these Chinese CLS patients are comparable to what has been described in other ethnicities.
A Pyridine–Pyridine Cross‐Coupling Reaction via Dearomatized Radical Intermediates
Authors: Koniarczyk J. Luke , Greenwood Jacob W. , Alegre‐Requena Juan V. , Paton Robert S. , McNally Andrew 
Published: August 2019

AbstractA pyridine–pyridine coupling reaction has been developed between pyridyl phosphonium salts and cyanopyridines using B2pin2 as an electron‐transfer reagent. Complete regio‐ and cross‐selectivity are observed when forming a range of valuable 2,4′‐bipyridines. Phosphonium salts were found to be the only viable radical precursors in this process, and mechanistic studies indicate that the process does not proceed through a Minisci‐type coupling involving a pyridyl radical. Instead, a radical–radical coupling process between a boryl phosphonium pyridyl radical and a boryl‐stabilized cyanopyridine radical explains the C−C bond‐forming step.
An Ultrastable Matryoshka [Hf13] Nanocluster as a Luminescent Sensor for Concentrated Alkali and Acid
Authors: Kang Xiao‐Min , Hu Han‐Shi , Wu Zhi‐Lei , Wang Jia‐Qi , Cheng Peng , Li Jun , Zhao Bin 
Published: August 2019

AbstractStable metal clusters that can resist both highly concentrated acid and alkali are unknown. Herein, we present a discrete neutral cluster, Hf13(μ4‐O)8(OCH3)36 (1), which features extraordinary chemical stability by preserving its crystalline state in concentrated aqueous solutions of both acid (10 m HNO3) and alkali (20 m boiling NaOH). Importantly, 1 can serve as a luminescent probe for detecting both concentrated alkali (20 m NaOH) and strong acid (1 m HNO3) with high selectivity and repeatability. DFT studies of the electronic structure and bonding revealed that 1 has an extremely large HOMO–LUMO gap due to strong d π–p π bonding that accounts for the ultrahigh stability.
Voltage‐Switchable HCl Transport Enabled by Lipid Headgroup–Transporter Interactions
Authors: Wu Xin , Small Jennifer R. , Cataldo Alessio , Withecombe Anne M. , Turner Peter , Gale Philip A. 
Published: August 2019

AbstractSynthetic anion transporters that facilitate transmembrane H+/Cl− symport (cotransport) have anti‐cancer potential due to their ability to neutralize pH gradients and inhibit autophagy in cells. However, compared to the natural product prodigiosin, synthetic anion transporters have low‐to‐modest H+/Cl− symport activity and their mechanism of action remains less well understood. We report a chloride‐selective tetraurea macrocycle that has a record‐high H+/Cl− symport activity similar to that of prodigiosin and most importantly demonstrates unprecedented voltage‐switchable transport properties that are linked to the lack of uniport activity. By studying the anion binding affinity and transport mechanisms of four other anion transporters, we show that the lack of uniport and voltage‐dependent H+/Cl− symport originate from strong binding to phospholipid headgroups that hampers the diffusion of the free transporters through the membrane, leading to an unusual H+/Cl− symport mechanism that involves only charged species. Our work provides important mechanistic insights into different classes of anion transporters and a new approach to achieve voltage‐switchability in artificial membrane transport systems.
Highly Stable Lithium Metal Anode Interface via Molecular Layer Deposition Zircone Coatings for Long Life Next‐Generation Battery Systems
Authors: Adair Keegan R. , Zhao Changtai , Banis Mohammad Norouzi , Zhao Yang , Li Ruying , Cai Mei , Sun Xueliang 
Published: August 2019

AbstractHerein, molecular layer deposition is used to form a nanoscale “zircone” protective layer on Li metal to achieve stable and long life Li metal anodes. The zircone‐coated Li metal shows enhanced air stability, electrochemical performance and high rate capability in symmetrical cell testing. Moreover, as a proof of concept, the protected Li anode is used in a next‐generation Li‐O2 battery system and is shown to extend the lifetime by over 10‐fold compared to the batteries with untreated Li metal. Furthermore, in‐situ synchrotron X‐ray absorption spectroscopy is used for the first time to study an artificial SEI on Li metal, revealing the electrochemical stability and lithiation of the zircone film. This work exemplifies significant progress towards the development and understanding of MLD thin films for high performance next‐generation batteries.
Rheological study of quaternary ammonium‐containing star‐shaped polylactic acid
Authors: Belkhir Kedafi , Majesté Jean‐Charles , Jegat Corinne , Taha Mohamed 
Published: August 2019

ABSTRACTQuaternary ammonium‐containing star‐shaped polylactic acid (PLA‐Q) is analyzed in melt rheology and found to follow a clustering behavior. The viscosity of this polymer is largely higher than its analog, of the same structure, without ammonium ions. This difference is attributed to physical interactions taking place between the ammoniums and hindering the flow of the melt polymer. The frequency sweeps of the storage (G′) and loss (G′′) modulus of the melt PLA‐Q are achieved at different temperatures and different shearing times. The iso‐temperature and iso‐time superposition of the resulting curves were achieved using, respectively, a temperature and a time shift factors, this superposition allowed the determination of the flow activation energy; its value corresponds to an ionic process confirming the ionic interactions. When the two shift factors are used simultaneously, a unique master curve of both G′ and G′′ is obtained; this curve follows the Rouse model indicating the presence of two types of ionic associations within the melt polymer: a large number of multiplets having small size and a small number of clusters of larger size. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48337.