bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proopiomelanocortin (POMC) sequencing and developmental delay: Preliminary evidence for a SNP in the 3’ UTR region of the POMC gene—Possible relevance for biological risk and self-injurious behavior
Authors: Damerow John A. , Tervo Raymond C. , Ehrhardt Michael , Panoskaltsis-Mortari Angela , Symons Frank J. 
Published: July 2018

AbstractThe proopiomelanocortin (POMC) molecule has been implicated in models of self-injurious behavior (SIB) in neurodevelopmental disorders, but it has never been specifically sequenced in search of base specific polymorphisms. The empirical focus of this preliminary study was to sequence thePOMCgene in 11 children (mean age = 41.8 months, range = 12–60 months; 73% male) with clinical concerns regarding global developmental delay, 5 with reported self-injury. Genomic DNA was extracted from blood samples, and thePOMCgene was amplified by specific oligonucleotide primers via polymerase chain reaction. The amplified gene products were sequenced by the University of Minnesota Genomic Center, and the results were analyzed using Sequencher software. A single nucleotide polymorphism (SNP), 1130 C&gt;T, was found in the 3’ untranslated region (UTR) of two samples (one of whom had SIB). The program TargetScanHuman was used to predict the function of this mutation. Variant c.1130 C&lt;T was predicted to be located in the target site of two microRNAs (miRNAs; hsa-mir-3715 and hsa-mir-1909), and the variant allele T may result in an increased minimum free energy for the two miRNAs. Further work with much larger samples is needed to continue the investigation ofPOMC’s possible function as a risk factor for the development of SIB in children with developmental delay/disability. The findings presented in this study show that the SNP found in the 3’ UTR could alter the binding of miRNAs toPOMC3'UTR, thus, increasingPOMCexpression and affecting several biological systems with high relevance to the biology of self-injury. There was a significant difference in β-endorphin levels between SIB (M= 169.25 pg/mL) and no SIB (M= 273.5 pg/mL,SD= 15.2) cases (p&lt; .01). Intervention implications are tied to prior observations of individual differences among SIB responders and nonresponders to treatment with the opioid antagonist naltrexone. Stratifying individuals with SIB byPOMCmutation status may provide a potential tailoring-like variable to guide the selection of who is more (or less) likely to respond to opiate antagonist treatment. Currently, opioid antagonistic treatment for SIB is empiric (trial and error).
Turán Number of an Induced Complete Bipartite Graph Plus an Odd Cycle
Authors: ERGEMLIDZE BEKA , GYŐRI ERVIN , METHUKU ABHISHEK 
Published: July 2018

Let k ⩾ 2 be an integer. We show that if s = 2 and t ⩾ 2, or s = t = 3, then the maximum possible number of edges in a C2k+1-free graph containing no induced copy of Ks,t is asymptotically equal to (t − s + 1)1/s(n/2)2−1/s except when k = s = t = 2.This strengthens a result of Allen, Keevash, Sudakov and Verstraëte [1], and answers a question of Loh, Tait, Timmons and Zhou [14].
Young people, precarious work, and the development of youth employment policies in Japan
Authors: Song Jiyeoun 
Published: July 2018

AbstractJapan's labor market has been under severe strain over the past few decades, driven by its protracted economic recession, a series of labor market reforms, and changing labor management practices. Confronting these new challenges, an increasing number of young people have had extreme difficulties in searching for decent and stable jobs in the labor market, trapped in the vicious cycle of precarious employment. This paper examines the deterioration of employment and labor market conditions for Japan's youth after the collapse of the asset bubble in the early 1990s and the government's policy efforts to address these concerns, especially since the early 2000s, a period during which it has initiated a wide array of youth employment and labor market policies. In particular, it analyzes variations in policy target group and goal across different measures and evaluates the effectiveness and limitations of these programs in dealing with youth problems in the labor market. This paper argues that while the government has promoted various policy tools to help young people become economically and socially independent individuals, it has gradually shifted its policy focus toward human capital development for growth and industrial competitiveness as a way of revitalizing Japan's troubling economy.
Reconstructing hierarchy as the key international relations concept and its implications for the study of Japanese national identity
Authors: Kolmaš Michal 
Published: July 2018

AbstractFor the last few decades, the discipline of international relations has been littered with anarchy. Since Waltz'sTheory of International Politics, it has been assumed that states are formally equal sovereign unitary actors operating in an anarchic world system and that their identities and interests are defined by the very existence of anarchy. This article shatters this conception. It offers a ‘hierarchical worldview’ in order to illustrate that the very concepts of state, sovereignty, and anarchy are discursive creations inherently tied to the practice of hierarchy. I use a case study of Japanese national identity to illustrate this practice. The narratives of Japan as an autonomous and sovereign state were inextricably linked to Japan's hierarchical relationship toward Asia and the West (pre-war) and the USA (post-war). Japan's sovereignty and autonomy were then formulated within the practice of hierarchy.
On the low detection efficiency of disk water megamasers in Seyfert 2 AGN
Authors: Masini Alberto , Comastri Andrea 
Published: July 2018

AbstractDisk megamasers are a unique tool to study active galactic nuclei (AGN) sub-pc environment, and precisely measure some of their fundamental parameters. While the majority of disk megamasers are hosted in heavily obscured (i.e., Seyfert 2, Sy2) AGN, the converse is not true, and disk megamasers are very rarely found even in obscured AGN. The very low detection rate of such systems in Sy2 AGN could be due to the geometry of the maser beaming, which requires a strict edge-on condition. We explore some other fundamental factors which could play a role in a volume-limited survey of disk megamasers in Sy2 galaxies, most importantly the radio luminosity.
Astrometric VLBI Observations of the Galactic LPVs, Miras, and OH/IR stars
Authors: Nakagawa Akiharu , Kurayama Tomoharu , Orosz Gabor , Burns Ross A. , Oyama Tomoaki , Nagayama Takumi , Miyata Takashi , Sekido Mamoru , Baba Junichi , Wada Kiichi 
Published: July 2018

AbstractStudies of Galactic LPVs based on astrometric VLBI are presented. We use a VLBI array, “VERA”, to measure parallaxes and calibrate the K-band period luminosity relation (PLR) of the Galactic Miras. Since the PLR offers a distance indicator, its calibration is crucial to reveal their spatial distribution. Parallaxes of dozens of LPVs are presented. For the longer period stars, the mass-loss is high and the stars are obscured and recognized as OH/IR stars. We estimated mid-infrared absolute magnitudes of dozens of OH/IR stars and found that they show a loose concentration around −14 mag at λ of 11.6 μm, indicating an existence of PLR for OH/IR stars. Astrometry of OH/IR stars will also help us to study non-steady spiral arms as proposed from the latest simulation study of the galactic dynamics. We will start astrometric VLBI observation of two OH/IR stars NSV25875 and OH127.8+0.0 at 43 GHz with VERA.
Water masers as signposts of extremely young planetary nebulae
Authors: Gómez José F. , Miranda Luis F. , Uscanga Lucero , Suárez Olga 
Published: July 2018

AbstractOnly five planetary nebulae (PNe) have been confirmed to emit water masers. They seem to be very young PNe. The water emission in these objects preferentially traces circumstellar toroids, although in K 3-35 and IRAS 15103-5754, it may also trace collimated jets. We present water maser observations of these two sources at different epochs. The water maser distribution changes on timescales of months to a few years. We speculate that these changes may be due to the variation of the underlying radio continuum emission, which is amplified by the maser process in the foreground material.
Towards continuous viewing of circumstellar maser sources over decades
Authors: Imai Hiroshi 
Published: July 2018

AbstractThe brightness of maser features are fascinating and give valuable insight for circumstellar physics of oxygen-rich, intermediate-mass stars, in particular the final evolution of circumstellar envelopes (CSEs). The variety of accompanying masers such as SiO, H2O, and OH in the CSEs may provide unique probes into different stages of rapid CSE evolution. However, with only sparse monitoring of these masers one can sometimes find it difficult to accurately interpret their spatio-kinematics, origins and excitation mechanisms. Examples can be seen in the variety of proposed models for water masers associated with “water fountains” and for silicon-monoxide masers. In order to better understand these issues, one needs to consider continuous monitoring of the individual maser gas clumps over a few stellar cycles or episodic ejection events. Here I present our previous long-term monitoring observations, especially for the water fountain source W43A. Our current efforts involve programs of intensive monitoring observations of circumstellar maser sources over decadal time periods. These programs with the East Asia VLBI Network observe H2O and SiO maser lines simultaneously mapped at high cadence (2–8 weeks) with VLBI observations.
Distances of Stars by mean of the Phase-lag Method
Authors: Etoka Sandra , Engels Dieter , Gérard Eric , Richards Anita M. S. 
Published: July 2018

AbstractVariable OH/IR stars are Asymptotic Giant Branch (AGB) stars with an optically thick circumstellar envelope that emit strong OH 1612 MHz emission. They are commonly observed throughout the Galaxy but also in the LMC and SMC. Hence, the precise inference of the distances of these stars will ultimately result in better constraints on their mass range in different metallicity environments. Through a multi-year long-term monitoring program at the Nancay Radio telescope (NRT) and a complementary high-sensitivity mapping campaign at the eMERLIN and JVLA to measure precisely the angular diameter of the envelopes, we have been re-exploring distance determination through the phase-lag method for a sample of stars, in order to refine the poorly-constrained distances of some and infer the currently unknown distances of others. We present here an update of this project.
Masers! What can VLBI do for you?
Authors: Colomer Francisco , van Langevelde Huib 
Published: July 2018

AbstractVery Long Baseline Interferometry (VLBI) is providing key information to the study of maser processes in the Universe, from star formation regions or circumstellar envelopes around evolved stars, to Galactic structure and cosmology, through precise astrometry. VLBI networks offer various capabilities and, most importantly, support to users, to ensure that these infrastructures are fully accesible and that the best science can emerge. In this paper we describe the advances in VLBI that enable exciting maser studies.
Isotopic SiO Maser Emission from the BAaDE Survey
Authors: Claussen M. J , Morris M. R. , Pihlström Y. M. , Sjouwerman L. O. ,   the BAaDE Team
Published: July 2018

AbstractThe Bulge Asymmetries and Dynamical Evolution (BAaDE) project aims to map the positions and velocities of up to ~20,000 late-type stars with SiO maser emission along the full Galactic plane, with a large concentration in the Galactic Bulge and inner Galaxy. Both J = 1 → 0 and J = 2 → 1 transitions using the Very Large Array (VLA) and the Atacama Large Millimeter Array (ALMA) are being observed. In the VLA observing setup, in addition to the 28SiO, v = 1 and v = 2J = 1 → 0 maser transitions, the bandwidth was wide enough to include the J = 1 → 0 transitions of the rare isotopologues of the SiO molecule in both the ground and vibrationally excited states: 29SiO, v = 0, 30SiO, v = 0, 29SiO, v = 1, and 29SiO, v = 2. Approximately 10% of the initial ~3500 targets of the project show maser emission from at least one of these lines. Some of these stars (with isotopic maser emission) show high radial velocities which implies that they are indeed in the Galactic Bulge or inner Galaxy (i.e. not foreground objects). We present line profiles, refined detection statistics, and the implications of the detection of the isotopic maser emission on pumping schemes that have been previously presented.
Methanol Masers in the Andromeda Galaxy
Authors: Pihlström Ylva M. , Sjouwerman Loránt O. 
Published: July 2018

AbstractIs M31 going to collide with the Milky Way, or spiral around it? Determining the gravitational potential in the Local Group has been a challenge since it requires 3D space velocities and orbits of the members, and most objects have only had line-of-sight velocities measured. Compared to the less massive group members, the transverse velocity of M31 is of great interest, as after the Milky Way, M31 is the most dominant constituent and dynamic force in the Local Group. Proper motion studies of M31 are preferentially done using masers, as continuum sources are much weaker, and are enabled through the high angular resolution provided by VLBI in the radio regime. The challenges of achieving high astrometric accuracy at high VLBI frequencies (> 20 GHz) makes observations at lower frequencies attractive, as long as sufficient angular resolution is obtained. In particular, we have discovered 6.7 GHz methanol masers in M31 using the VLA, and here we will address their feasibility as VLBI proper motion targets using a set of global VLBI observations.
The extraordinary outburst in NGC6334I-MM1: dimming of the hypercompact HII region and destruction of water masers
Authors: Brogan Crystal L. , Hunter Todd R. , MacLeod Gordon , Chibueze James O. , Cyganowski Claudia J. 
Published: July 2018

AbstractWe present subarcsecond resolution pre- and post-outburst JVLA continuum and water maser observations of the massive protostellar outburst source NGC6334I-MM1. The continuum data at 5 and 1.4 cm reveal that the free-free emission powered by MM1B, modeled as a hypercompact HII region from our 2011 JVLA data, has dropped by a factor of 5.4. Additionally, the water maser emission toward MM1, which had previously been strong (500 Jy) has dramatically reduced. In contrast, the water masers in other locations in the protocluster have flared, with the strongest spots associated with CM2, a non-thermal radio source that appears to mark a shock in a jet emanating 2″ (2600 au) northward from MM1. The observed quenching of the HCHII region suggests a reduction in uv photon production due to bloating of the protostar in response to the episodic accretion event.
MultiView High Precision VLBI Astrometry at Low Frequencies
Authors: Rioja M. , Dodson R. , Orosz G. , Imai H. 
Published: July 2018

AbstractObservations at low frequencies (<8GHz) are dominated by distinct direction dependent ionospheric propagation errors, which place a very tight limit on the angular separation of a suitable phase referencing calibrator and astrometry. To increase the capability for high precision astrometric measurements an effective calibration strategy of the systematic ionospheric propagation effects that is widely applicable is required. The MultiView technique holds the key to the compensation of atmospheric spatial-structure errors, by using observations of multiple calibrators and two dimensional interpolation. In this paper we present the first demonstration of the power of MultiView using three calibrators, several degrees from the target, along with a comparative study of the astrometric accuracy between MultiView and phase-referencing techniques. MultiView calibration provides an order of magnitude improvement in astrometry with respect to conventional phase referencing, achieving ~100micro-arcseconds astrometry errors in a single epoch of observations, effectively reaching the thermal noise limit.
Ubiquitous millimeter-wavelength Class I methanol masers associated with massive (proto)stellar outflows: ALMA and SMA results
Authors: Cyganowski C. J. , Hannaway D. , Brogan C. L. , Hunter T. R. , Zhang Q. 
Published: July 2018

AbstractWe report the discovery of widespread millimeter-wavelength Class I methanol maser emission associated with protostellar molecular outflows in the massive (proto)cluster G11.92−0.61. Our ~0.5″-resolution SMA and ALMA observations of the 229 GHz and 278 GHz Class I transitions reveal seven and twelve candidate masers, respectively: all 229 GHz masers have 278 GHz counterparts, and five are also coincident with 44 GHz Class I masers previously detected with the VLA. For paired masers, the peak intensities at 229 GHz and 278 GHz are correlated. We also find tentative evidence for a correlation between the strength of millimeter-wavelength Class I maser emission and the energy of the associated molecular outflow.
H2O MegaMasers: RadioAstron success story
Authors: Baan Willem , Alakoz Alexey , An Tao , Ellingsen Simon , Henkel Christian , Imai Hiroshi , Kostenko Vladimir , Litovchenko Ivan , Moran James , Sobolev Andrej , Tolmachev Alexander 
Published: July 2018

AbstractThe RadioAstron space-VLBI mission has successfully detected extragalactic H2O MegaMaser emission regions at very long Earth to space baselines ranging between 1.4 and 26.7 Earth Diameters (ED). The preliminary results for two galaxies, NGC 3079 and NGC 4258, at baselines longer than one ED indicate masering environments and excitation conditions in these galaxies that are distinctly different. Further observations of NGC 4258 at even longer baselines are expected to reveal more of the physics of individual emission regions.
MASERS: A Python package for statistical equilibrium calculations applied to masers
Authors: van Rooyen R. , van der Walt D. J. 
Published: July 2018

AbstractThe study of astrophysical maser formation provides a useful probe of the chemical composition and physical conditions of the sources they are observed in. This exploration requires continuously solving the SE equations for the populations of the energy levels in search of conditions that will produce an inversion. After evaluation of available implementations applying the Escape Probability approximation, the masers solver was developed to provide an efficient and robust matrix inversion calculation. This open source package is hosted at https://bitbucket.org/ruby_van_rooyen/masers.
Full polarization analysis of OH masers at 18-cm toward W49 A star forming region
Authors: Asanok K. , Kramer B. Hutawarakorn , Etoka S. , Gray M. , Richards A. M. S. , Gasiprong N. , Naochang N. 
Published: July 2018

AbstractW49 A is a star-forming region (SFR) found in the constellation of Aquila. It contains 3 active regions: W49 North (W49 N), W49 South West (W49 SW) and W49 South (W49 S). We present preliminary results from two epochs (e-)MERLIN observations of all ground-state OH masers towards the star-forming region (SFR) complex W49 A. The first epoch of observations was done in full-polarization mode with MERLIN in 2005 while the second epoch was obtained only in dual circular polarization during the test observations of the upgraded e-MERLIN in 2013. The overall maser spatial distributions in both epochs are in good agreement. We found several new high velocity maser features up to +34 km s−1 and −28 km s−1. The magnetic field strengths are between 1.1 to 10.8 mG. All three sources show evidence of magnetic field reversal.
Dynamics of jet/outflow driven by high-mass young stellar object revealed by KaVA 22 GHz water maser observations
Authors: Kim Jungha , Hirota Tomoya , Kim Kee-Tae , Sugiyama Koichiro ,   KaVA Science Working Group for Star-formation
Published: July 2018

AbstractWe have started survey observations of the 22 GHz water maser sources associated with high-mass young stellar objects (HM-YSOs) as a part of the KaVA (KVN and VERA Array) large program (LP). The aim of our LP is to understand dynamical evolution of jets/outflows from HM-YSOs by analyzing 3D velocity structures of water maser features. In the first year (2016-2017), an imaging survey toward 25 HM-YSOs has been conducted and the 22 GHz water masers are detected toward 21 sources. Spatial distributions of maser features for individual sources are mapped. To complement physical properties in the vicinity of HM-YSOs, we have carried out ALMA cycle 3 observations of thermal molecular lines and continuum emissions toward 11 selected samples. Summary of the KaVA first year observations and the initial results from the ALMA toward one of our targets, G25.82-0.17, are reported.
Maser science with the Square Kilometre Array
Authors: Bonaldi Anna 
Published: July 2018

AbstractThe Square Kilometre Array (SKA), reaching a collecting area of one square kilometre, will be the world’s largest radio telescope. Even in its first stage of deployment (SKA1, whose construction will be completed in 2026) it will enable transformational science on a very broad range of scientific objectives. Amongst them, there is the investigation of several Galactic and extra-galactic Masers. In this paper I will present the status of the SKA project and I will describe the capabilities of the SKA, with a focus on those that are more relevant for Maser science.
Periodic masers in massive star forming regions
Authors: Goedhart S. , van Rooyen R. , van der Walt D. J. , Maswanaganye J. P. , MacCleod G. C. , Sanna A. 
Published: July 2018

AbstractThe first periodic Class II methanol maser was reported on in 2003. Since that time, a number of different monitoring programmes have found periodic masers, as well as other modes of variability. In a few cases, periodicity has been found in other maser species such as formaldehyde and water. Several distinct characteristics of light curves have been noted, possibly pointing to different underlying mechanisms for periodicity if one assumes a linear response to incoming radiation. I will give a brief overview of the known periodic sources, discuss current theories, and present new results obtained from monitoring mainline hydroxyl masers using the seven-element Karoo Array Telescope (KAT-7) during its science verification phase.
The CepHeus-A Star formation and proper Motions (CHASM) Survey
Authors: Sanna Alberto 
Published: July 2018

AbstractThe “CepHeus-A Star formation and proper Motions” (CHASM) survey is a large project consisting of a combination of astrometric Very Long Baseline Array (VLBA) and Jansky Very Large Array (VLA) observations, to map both the stellar and dense molecular gas components in the star-forming region Cepheus A. With the VLBA, we make use of the CH3OH and H2O maser emission in the vicinity of Cepheus A HW2, in order to measure accurate proper motions and parallax distances to both T Tauri stars and massive young stellar objects (YSOs) belonging to the same star-forming region. With the Jansky VLA, we make use of the interstellar thermometer NH3, in order to image the molecular clump surrounding Cepheus A HW2 and to determine its physical conditions. By combining these informations all together, we can provide, for instance, a direct measurement of the Bondi-Hoyle accretion radius for a massive young star, namely, HW2.