bluuebunny/crossref_metadata_2025_split huggingface dataset:
Warfarin control in Hong Kong clinical practice
Authors: Lam Amy SM , Lee Isis MH , Mak Ka Shing , Yan Bryan PY , Lee Vivian WY 
Published: September 2019

Abstract
Objectives: Time-in-therapeutic range (TTR) assesses safety and effectiveness of warfarin therapy using international normalized ratio (INR). This study aimed to investigate the status of TTR in Hong Kong and patients’ economic and clinical outcomes. Predictors of poor warfarin control and patient’s knowledge in warfarin therapy were assessed.
Methods: A five-month observational study was conducted in Prince of Wales Hospital in Hong Kong. The TTRs calculated using Caucasian and Japanese therapeutic range were examined among patients on warfarin for at least one year. Patients’ knowledge was assessed using the Oral Anticoagulation Knowledge (OAK) test.
Results: A total of 259 patients were included in this study, with 174 of them completed the OAK test. Using Caucasian therapeutic range, calculated mean TTR was 40.2 ± 17.1%, compared that of 49.1 ± 16.1% with Japanese therapeutic range (P<0.001). Mean TTR in patients with atrial fibrillation was higher than those with prosthetic heart valve (p<0.001). Predictability of TTR on clinical outcomes and economic outcomes was comparable between Caucasian and Japanese therapeutic range. Patients with ideal TTR had fewer clinical complications and lower warfarin-related healthcare costs. Patients with younger age, concurrent use of aspirin, frusemide, famotidine, pantoprazole and simvastatin were associated with poorer TTR. Mean score of OAK test was 54.1%. Only 24 patients (13.8%) achieved the satisfactory overall score of ≥75% in the test.
Conclusion: Warfarin use in Hong Kong patients was poorly controlled regardless of indication. Patients’ knowledge towards warfarin use was suboptimal. More education to patients on warfarin use is warranted.
Genetic segregation for male body coloration and female mate preference in the guppy
Authors: Sato Aya , Kawata Masakado 
Published: September 2019

Abstract
Objective The purpose of this study was to segregate the genetic lines responsible for the orange area of coloration in males and the response to orange coloration exhibited by females in the guppy (Poecilia reticulata) through artificial selection. This study is part of a project that uses QTL-seq to search for candidate genes involved in male orange coloration and female response to male coloration. We created two lines: high-selected lines of males having large areas of orange spots and of females with high response to male orange coloration; and low-selected lines of males having small areas of orange spots and of females with low response to male orange coloration.Results The male orange area and the female response became significantly different between high- and low-selected lines after three generations of artificial selection. This indicates that the differences in the frequencies of alleles at loci affecting the orange area and the female response between the lines increased over the generations through selection.
Process Evaluation of Decontamination, Cleaning and Sterilization of medical instruments at public health centers of Mekelle zone, Tigray, Ethiopia, 2018
Authors: Gebremichael Byin Tewolde , Wuneh Alem Desta , Ashebr Mengistu Mitiku 
Published: September 2019

Abstract
Background: In Ethiopia, the prevalence of health care associated infection is high. Thus, implementing infection prevention activities has an important role in minimizing those infections. One of the activities of infection prevention is proper decontamination, cleaning and sterilization of medical instruments. In order to improve the quality of this intervention, generating evidences through monitoring and evaluation is indispensible. Therefore the key stakeholders have reached an agreement to conduct this process evaluation. Objective: To assess the implementation status of decontamination, cleaning and sterilization process of medical instruments in the public health centers of Mekelle zone, Tigray. Method: Descriptive study design was employed in this evaluation study. The evaluation was conducted in public health centers of Mekelle zone from January, 2017 to June, 2017. For the quantitative part, observation of health care workers’ practice using pre tested questionnaire was conducted. As a complement, key informant interviews were also conducted. Collected quantitative data were checked, coded and entered into SPSS version 20 for analysis. Frequencies, Mean, percentage, tables were used for results presentation and qualitative data were coded, categorized and finally conceptualized/give meaning. Result: Availability, compliance and safety of health care workers were used to evaluate the implementation of the intervention. Accordingly, availability of resources in the studied health centers has been rated as good ( 74.2%). And compliance level of health care workers has found to be fair ( 66.1% ). However, health care workers had poor practice in separating soiled from clean instruments, immersing of contaminated instruments in 0.5% chlorine solution for the correct duration and using oldest packs first. About practice of safety by the health care workers has found to be poor ( 48% ). In general, the overall implementation status of the service had been judged as fair ( 63.4 ). Conclusion: According the judgment criteria, the overall implementation
Quantification of the forecast uncertainty using conditional probability and updating models
Authors: Ba Huanhuan , Guo Shenglian , Zhong Yixuan , He Shaokun , Wu Xushu 
Published: September 2019

AbstractQuantifying forecast uncertainty is of great importance for reservoir operation and flood control. However, deterministic hydrological forecasts do not consider forecast uncertainty. This study develops a conditional probability model based on copulas to quantify forecast uncertainty. Three updating models, namely auto-regressive (AR) model, AR exogenous input model, and adaptive neuro fuzzy inference system model, are applied to update raw deterministic inflow forecasts of the Three Gorges Reservoir on the Yangtze River, China with lead times of 1d, 2d, and 3d. Results show that the conditional probability model provides a reasonable and reliable forecast interval. The updating models both enhance the forecast accuracy and improve the reliability of probabilistic forecasts. The conditional probability model based on copula functions is a useful tool to describe and quantify forecast uncertainty, and using an updating model is an effective measure to improve the accuracy and reliability of probabilistic forecast.
A systematic comparison of statistical and hydrological methods for design flood estimation
Authors: Okoli Kenechukwu , Mazzoleni Maurizio , Breinl Korbinian , Di Baldassarre Giuliano 
Published: September 2019

Abstract
We compare statistical and hydrological methods to estimate design floods by proposing a framework that is based on assuming a synthetic scenario considered as ‘truth’ and use it as a benchmark for analysing results. To illustrate the framework, we used probability model selection and model averaging as statistical methods, while continuous simulations made with a simple and relatively complex rainfall–runoff model are used as hydrological methods. The results of our numerical exercise show that design floods estimated by using a simple rainfall–runoff model have small parameter uncertainty and limited errors, even for high return periods. Statistical methods perform better than the linear reservoir model in terms of median errors for high return periods, but their uncertainty (i.e., variance of the error) is larger. Moreover, selecting the best fitting probability distribution is associated with numerous outliers. On the contrary, using multiple probability distributions, regardless of their capability in fitting the data, leads to significantly fewer outliers, while keeping a similar accuracy. Thus, we find that, among the statistical methods, model averaging is a better option than model selection. Our results also show the relevance of the precautionary principle in design flood estimation, and thus help develop general recommendations for practitioners and experts involved in flood risk reduction.
Highly effective removal of Cu(II) in aqueous solution by using mesoporous TiO2
Authors: Chen Daying , Tu Nasi , Si Changkun , Yin Meilin , Wang Xiaohui 
Published: September 2019

Abstract
Mesoporous TiO2 has been prepared by a brief and simple sol–gel processing and applied for the removal of Cu(II) from aqueous solution. The adsorption behavior of mesoporous TiO2 for Cu(II) was investigated using batch experiments. Results showed that the pseudo-second-order model and Langmuir isotherm were more accurate to describe the kinetics process and adsorption isotherm. Mesoporous TiO2 adsorbent displayed excellent Cu(II) adsorption efficiency (195.52mg g−1). The thermodynamic parameters showed that the adsorption was spontaneous and endothermic. It was also found that mesoporous TiO2 could be used at least seven times without obvious loss of its original adsorption efficiency. Therefore, the obtained mesoporous TiO2 could be employed as an effective and low-cost adsorbent for removal of Cu(II) from contaminated effluents.
Cost-effective removal of COD in the pre-treatment of wastewater from the paper industry
Authors: Boguniewicz-Zablocka Joanna , Klosok-Bazan Iwona , Naddeo Vincenzo , Mozejko Clara A. 
Published: September 2019

Abstract
The present paper reveals results of research for cost-effective removal of chemical oxygen demand (COD) contained in industrial paper mill effluent. Not only process efficiency but also wastewater treatment costs are discussed. Different pre-treatment processes are applied aiming to investigate the COD removal before discharge to the municipal sewage network. The objective of this paper is to find the optimal operating conditions for the coagulation process. The effects of key operational parameters, including the type of coagulant, initial pH, temperature and coagulant dose, on COD percentage removal were investigated. The laboratory experiments confirmed the high efficiency of chemically enhanced mechanical treatment towards COD. The data obtained show that even low dose of chemicals provides sufficient COD reduction. The initial pH of the wastewater had a significant impact on the COD removal. Under the optimal operational conditions (pH = 7.5, T = 18 °C) the treatment of wastewater from paper industries by coagulation has led to a reduction of 70% COD for wastewater discharged. In terms of the investigated paper industry wastewater, polyaluminium chloride appears to be most suitable for treatment of high COD concentration. However, in an economic evaluation of requirements for wastewater treatment, operating costs and associated saving were such that PAX was more favourable.
Formulation, Development and Scale-Up of Fixed-Dose Combination Tablets Containing Zidovudine, Lamivudine and Nevirapine
Authors: Lavra Zênia Maria Maciel , de Medeiros Flávia Patrícia Morais , da Silva Rosali Maria Ferreira , Rosa Talita Atanazio , Wanderley Sales Victor de Albuquerque , Barros Silva Laysa Creusa Paes Barreto , de Sousa André Luiz Moreira Domingues , de Lima Leduar Guedes , Rolim Larissa Araújo , Neto Pedro José Rolim 
Published: September 2019

Background:
The development of antiretroviral associations in a single dosage form aims
to ensure improved efficacy, low costs and better adherence to treatment.

Objective:
This work performed the pharmacotechnical development, coating, and stability studies
of fixed-dose combination tablets of zidovudine, lamivudine and nevirapine (300 + 200 + 150 mg,
respectively).

Methods:
Qualitative and quantitative planning of diluents (101 and 250 microcrystalline cellulose,
spray-dried monohydrate lactose and corn starch) and coating polymers (Opadry white II HP® and
Instacoat Aqua Moistshield II®) were analyzed, and direct compression (DC) and wet granulation
(WG) methods were tested aiming the development of the pharmaceutical form. Quality control was
carried out according to the specifications set by official compendia. The chosen formulation was
scaled-up and the industrial batches were submitted to accelerated and long-term stability studies.

Results:
The batches obtained by WG met the requirements, using 101 microcrystalline cellulose,
corn starch and Opadry white II HP®
as excipients. The DC trial was not possible due to the need of
a greater ratio of excipients to improve formulation properties.

Conclusion:
Thus, this study brings a new therapeutic alternative for HIV treatment, contributing to
the development of another possibility to simplify drug administration.
ANALISIS PERAN GURU PPKn DALAM MEMBINA MORAL ANTIKORUPSI PESERTA DIDIK DI SMP NEGERI 2 PUCUK KABUPATEN LAMONGAN
Authors: Adi Raga Gawan Bagus , Yusuf Nurbani , Mansur M 
Published: September 2019

Raga, Gawan Bagus Adi. 2019. Analisis Peran Guru PPKn dalam Membina Moral Antikorupsi Peserta Didik di SMP Negeri 2 Pucuk Kabupaten Lamongan. Drs. Nurbani Yusuf, M.Si., Drs. M. Mansur, M.HTujuan dari penelitian ini adalah (1) mengetahui peran guru PPKn dalam membina moral antikorupsi peserta didik, (2) mengetahui bagaimana kendala yang dihadapi guru PPKn dalam membina moral antikorupsi peserta didik, dan (3) menganalisis peran yang tepat bagi guru PPKn dalam membina moral antikorupsi peserta didik agar selaras dengan upaya pemberantasan korupsi.Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif deskriptif. ini adalah penelitian deskriptif kualitatif. Alasan digunakannya pendekatan kualitatif deskriptif dengan maksud untuk menjelaskan dan mengungkapkan fakta yang terjadi di lingkungan sekolah, tepatnya pada saat pembelajaran di kelas. Tempat penelitian dilakukan di SMP Negeri 2 Pucuk yang terletak di Desa Kesambi, Kecamatan Pucuk, Kabupaten Lamongan. Teknik pengumpulan data yang digunakan dalam penelitian ini meliputi observasi, wawancara, dan dokumentasi. Analisis data yang digunakan adalah reduksi data, display data, dan verifikasi.Hasil dari penelitian ini adalah peran (1) guru PPKn dalam membina moral antikorupsi peserta didik adalah sebagai pendidik dan pengajar berperan melakukan transfer ilmu pengetahuan, mengajarkan, dan membimbing Pendidikan Antikorupsi diintegrasikan ke dalam Pendidikan Pancasila dan Kewarganegaraan. Selain itu guru berperan sebagai pengelola pembelajaran, guru PPKn harus menguasai berbagai metode pembelajaran dan memahami situasi belajar mengejar di dalam kelas. (2) Kendala yang dihadapi dalam pembinaan moral antikorupsi adalah masih adanya peserta didik yang kurang memperhatikan apa yang disampaikan oleh guru PPKn. (3) Solusi yang tepat agar peran guru PPKn dalam membina moral antikorupsi peserta didik adalah mengadakan pertemuan antar orang tua, wali kelas, guru, dan kepala sekolah.
Strategi presentasi diri pengguna instagram ditinjau dari tipe kepribadian
Authors: Rarasati Devia Balqis , Hudaniah Hudaniah , Prasetyaningrum Susanti 
Published: September 2019

Abstrak. Instagram merupakan salah satu tempat untuk presentasi diri. Presentasi diri yang berlebihan di instagram dapat membentuk identitas berbeda antara di dunia nyata dan online. Ada berbagai strategi dalam presentasi diri di media sosial atau bisa disebut strategi presentasi diri. Presentasi diri pengguna instagram memiliki tujuan berbeda. Hipotesis penelitan ini untuk mengetahui perbedaan strategi presentasi diri pengguna instagram antara tipe kepribadian ekstrovert dan introvert. Penelitian ini dilakukan pada 212 orang pengguna instagram berusia 18-24 tahun. Teknik pengambilan sampel yang digunakan yaitu menggunakan teknik non-probality sampling khususnya accidental sampling. Variabel peneltian menggunakan skala Self-Presentation Strategies via SNS dan Eysenck Personality Inventory A. Hasil perhitungan menggunakan teknik independent t-test ada perbedaan strategi presentasi diri pengguna instagram ekstrovert dan introvert. Pengguna instagram tipe kepribadian ekstrovert memiliki rata-rata lebih tinggi di bandingkan introvert (ingratiation M=10,015, supplication M=5,636, dan enhancement M=10,88). Namun, pada strategi presentasi diri ingratiation dan supplication tidak ditemukan perbedaan yang signifikan.Kata kunci: Instagram, Strategi presentasi diri, Tipe kepribadian Abstract. Instagram as social media platform has many functions, one of which is for self-presentation. An excessive self-presentation on Instagram may result in the formation different identity between real life and online. There are various strategies in self-presentation on social media which can be referred as self-presentation strategy. The self-presentation on instagram has different purposes. This study aims at finding the different of self-presentation strategy between extrovert and introvert. There were 212 instagram users aged 18-24 years old as the subjects of the study. Sampling technique was the sampling non-probability technique, with particular of accidental sampling. The variable were measured using Self-Presentation Strategies scale via SNS and Eysenck Personality Inventory A. The calculation result which used the independent t-test showed there was a different in using self-presentation strategy between the extrovert and introvert. The extrovert users had relative higher average value than the introvert ones (Ingratiation M=10.015, Supplication M=5.636, and Enhancement M=10.88). Yet, there was no significant different in self-presentation strategy between ingratiation and supplication.Keywords : Instagram, Personality type, Self presentation strategies
Plan S. Принять нельзя отказать.
Authors: Назаровец Сергей , Скалабан Алексей 
Published: September 2019

В недалеком будущем инициатива План S, возможно, в корне изменит
рынок научной периодики и мир откажется от подписной бизнес-модели в пользу
бизнес-модели открытого доступа. Такой переход ставит перед исследователями,
управленцами, библиотекарями и научными издателями из развивающихся стран
новые вызовы и задачи, поскольку подписные и публикационные политики этих стран
еще только находятся в процессе становления, но уже должны быть оперативно
переосмыслены и изменены в соответствии с веяниями Плана S. В этом исследовании
на примере публикаций ученых Беларуси и Украины в журналах издательства Elsevier
мы попытались оценить приблизительную стоимость и перспективы перехода этих
двух стран на открытую модель научной коммуникации. Мы пришли к выводу, что
сейчас Беларусь и Украина вкладывают недостаточное количество денег в науку для
осуществления перехода на открытую модель. Предложенная нами методика
подсчета суммы за публикацию в открытом доступе статей ученых страны может быть
использована в процессе подготовки трансформативных соглашений для
развивающихся стран.
Анализ белорусских научных журналов, индексируемых в Science Citation Index Expanded и Emerging Sources Citation Index
Authors: Скалабан А , Лазарев В , Юрик И , Лис П 
Published: September 2019

Рассмотрены наукометрические характеристики белорусских журналов, индексируемых в Science Citation Index Expanded в сравнении с журналами, относящимися к той же тематической категории и имеющими лучшие значения импакт-фактора, а также с журналами, имеющими значение импакт-фактора, соответствующее последней позиции второго квартиля (т.н. «журналы середины списка»).
Определено, во сколько раз значение импакт-фактора журнала той же предметной категории, который имеет наибольшее значение этого показателя, и значение импакт-фактора «журнала середины списка» превышает его значение у индексируемых белорусских журналов. Нас интересовало, сколько ссылок белорусский журнал «должен» получить «в дополнение» к уже полученным, чтобы иметь импакт-фактор, значение которого совпадало бы со значением такового у «журнала середины списка» журналов той же тематической категории.
Оценивались перспективы индексирования Science Citation Index Expanded тех белорусских журналов, которые пока представлены в Emerging Sources Citation Index. Редакционным органам рассматриваемых журналов даны рекомендации, направленные на укрепление позиций журналов в Science Citation Index Expanded или на перенос их в данную базу данных из Emerging Sources Citation Index.
Insulation Panels Made from Thermally Modified Bark
Authors: Pásztory Zoltán , Tsalagkas Dimitrios , Horváth Norbert , Börcsök Zoltán 
Published: September 2019

Abstract
Thermally treated and ground poplar bark was used as the raw material for pressed bark insulation panels. Bark chips were treated for one, two, and three hours at 180 °C after a slow warming, drying process. The physical and mechanical properties of the pressed panels were investigated and compared to each other and to the control panel made of untreated bark chips. Thermal conductivity showed slight deviations and ranged from 0.064 – 0.067 W·m−1·K−1. The MOR and MOE showed a significant increase of 100%. The internal bond increased by 27% while the water absorption and thickness swelling decreased by 53.8% and 69.1% respectively. Panel density did not change significantly because the target density was the same for every panel type. The mechanical and physical properties of thermal insulation panels made of heat-treated chips increased significantly.
Cubic Intuitionistic Structures Applied to Ideals of BCI-Algebras
Authors: Senapati Tapan , Jun Young Bae , Muhiuddin G. , Shum K. P. 
Published: September 2019

Abstract
In this paper, the notion of closed cubic intuitionistic ideals, cubic intuitionistic p-ideals and cubic intuitionistic a-ideals in BCI-algebras are introduced, and several related properties are investigated. Relations between cubic intuitionistic subalgebras, closed cubic intuitionistic ideals, cubic intuitionistic q-ideals, cubic intuitionistic p-ideals and cubic intuitionistic a-ideals are discussed. Conditions for a cubic intuitionistic ideal to be a cubic intuitionistic p-ideal are provided. Characterizations of a cubic intuitionistic a-ideal are considered. The cubic intuitionistic extension property for a cubic intuitionistic a-ideal is established.
Vanishing Ideals Over Odd Cycles
Authors: Uribe-Paczka M. Eduardo , Sarmiento Eliseo , Márquez Carlos Rentería 
Published: September 2019

Abstract
Let K be a finite field. Let X
* be a subset of the a ne space Kn
, which is parameterized by odd cycles. In this paper we give an explicit Gröbner basis for the vanishing ideal, I(X
*), of X
*. We give an explicit formula for the regularity of I(X
*) and finally if X
* is parameterized by an odd cycle of length k, we show that the Hilbert function of the vanishing ideal of X
* can be written as linear combination of Hilbert functions of degenerate torus.
Mitigating Hotspot Issue in WSN Using Sensor Nodes with Varying Initial Energy Levels and Quantification Algorithm
Authors: Balamurali R. , Kathiravan K. , Krishnan T. 
Published: September 2019

Abstract
A typical Wireless Sensor Network (WSN) uses multihop communication rather than direct transmission. In a multi-hop communication, the sensor node communicates the sensed data to its neighbor node, which is comparatively closer to the sink and the receiving node will forward the data to its neighbor node. This process continues until the data reaches the sink. Due to the multihop communication, the nodes closer to the sink have to transmit and receive more data and control packets compared to other nodes. Hence, the nodes closer to sink may deplete their energy at a faster rate and may die soon. This may create network isolation. This issue is called as the Hotspot problem. In this paper, we are proposing a Quantification algorithm for Sensor Nodes with varying Initial Energy Level to mitigate the Hotspot effect.