bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dye- and fluorescence-based assay to characterize symplastic and apoplastic trafficking in soybean (Glycime max L.) endosperm
Authors: Shih Ming-Der , Lin Jian-Shin , Fang Mei-Jane , Tsai Yuan-Ching , Hsing Yue-Ie C. 
Published: September 2019

AbstractBackgroundEndosperm is a triploid tissue in seed resulting from a sperm nucleus fused with the binucleate central cell after double fertilization. Endosperm may be involved in metabolite production, solute transport, nutrient storage, and germination. In the legume family (Fabaceae), with the greatest number of domesticated crops, approximately 60% of genera contain well-differentiated endosperm in mature seeds. Soybean seeds, the most important legume crop in the worlds, have endosperm surrounding embryos during all stages of seed development. However, the function of soybean endosperm is still unknown.ResultsFlow cytometry assay confirmed that soybean endosperm was triploid. Cytobiological observation showed that soybean endosperm cells were alive with zigzag-shape cell wall. Soybean endosperm cells allowed fusion proteins (42 kDa) to move from bombarded cells to adjacent unbombarded-cells. Such movement is not simple diffusion because the fusion proteins failed to move into dead cells. We used symplastic tracers to test the transport potential of soybean endosperm. Small organic dye and low-molecular-weight symplastic tracers revealed fast symplastic transport. After a treatment of an inhibitor of ATPase,N,N′-dicyclohexylcarbodiimide (DCCD), symplastic transport was blocked, but all tracers still showed fast apolopastic transport. The transport speed of 8-hydroxypyrene-1,3,6-trisulfonic acid in endosperm was 1.5 to 3 times faster than in cotyledon cells or Arabidopsis embryos.ConclusionsSoybean endosperm is a membrane-like, semi-transparent, and fully active tissue located between the seed coat and cotyledon. Soybean endosperm cells allowed macromolecules to move fast via plasmodesmata transport. The size exclusion limit is larger for soybean endosperm cells than its cotyledon or even Arabidopsis embryo cells. Soybean endosperm may be involved in fast and horizontal transport during the mid-developmental stage of seeds.
Recent progress in directed evolution of stereoselective monoamine oxidases
Authors: Duan Jiaqi , Li Beibei , Qin Youcai , Dong Yijie , Ren Jie , Li Guangyue 
Published: September 2019

AbstractMonoamine oxidases (MAOs) use molecular dioxygen as oxidant to catalyze the oxidation of amines to imines. This type of enzyme can be employed for the synthesis of primary, secondary, and tertiary amines by an appropriate deracemization protocol. Consequently, MAOs are an attractive class of enzymes in biocatalysis. However, they also have limitations in enzyme-catalyzed processes due to the often-observed narrow substrate scope, low activity, or poor/wrong stereoselectivity. Therefore, directed evolution was introduced to eliminate these obstacles, which is the subject of this review. The main focus is on recent efforts concerning the directed evolution of four MAOs: monoamine oxidase (MAO-N), cyclohexylamine oxidase (CHAO),D-amino acid oxidase (pkDAO), and 6-hydroxy-D-nicotine oxidase (6-HDNO).
A longitudinal analysis of the U.S. Air Force reserve officers’ training corps physical fitness assessment
Authors: Mackey Cameron S. , DeFreitas Jason M. 
Published: September 2019

Abstract

Background
The U.S. Air Force physical fitness assessment (PFA) is used to determine the overall fitness of their personnel. It is currently unknown to what extent the PFA scores of Reserve Officers’ Training Corps (ROTC) cadets are affected by mandatory physical training. The purpose of this investigation was to longitudinally examine the PFAs of ROTC cadets over a four-year period, evaluate the results across class ranks, and evaluate the sensitivity of the classification of the tests.

Methods
Air Force ROTC cadets performed the PFAs (abdominal circumference, 1-min pushups, 1-min sit-ups, and a 1.5-mile run) in both the spring (n = 26) and fall (n = 22) semesters. PFAs were compiled over a four-year period (Spring 2014 – Fall 2017) and were performed in accordance with Air Force Instruction 36–2905. A one-way repeated measures ANOVA was performed separately for the fall and spring groups for each dependent variable across the 4 years. Additionally, a one-way between groups ANOVA was performed for each dependent variable during the time point (fall 2015; N = 46) with the most recorded cadets for each class rank.

Results
Longitudinal assessments revealed a main effect of time (P = 0.010) on abdominal circumference; cadets had a smaller abdominal circumference in their freshman year than in their senior year. A main effect of time (P = 0.006) was also observed on sit-up quantity; cadets performed more sit-ups in their junior year than in their freshman year. Examining between class ranks during the same year (between-subjects ANOVA) revealed a main effect of class rank on sit-up quantity (P = 0.003); the freshmen completed fewer repetitions than the sophomores (P = 0.018) and the juniors did (P = 0.001).

Conclusion
The results indicated that only the sit-up component showed differences between class ranks. These findings suggest that the Air Force PFA may not be sensitive enough to detect changes in physical fitness or distinguish between class ranks regarding physical performance, even after years of training. This limitation may be in part due to the limited duration of training incorporated by the ROTC program (2 h per week), which provided a maintenance effect rather than improvement in physical performance. We recommend that more attention be directed to the efficacy of physical training, the sensitivity of measures included in the PFA, or both.
Occupational stress and job dissatisfaction with health work
Authors: de Sousa Camila Carvalho , de Araújo Tânia Maria , Lua Iracema , Gomes Mariana Rabelo 
Published: September 2019

Abstract

Objective
The purpose of this study is to evaluate the association between psychosocial aspects at work and dissatisfaction among health workers in five cities in Bahia, Brazil.

Methods
The evaluation was based on different models proposed to measuring occupational stress and possible combinations between them: demand-control model (DCM) and effort-reward imbalance (ERI). We conducted a cross-sectional epidemiological study including 3084 health workers. The analysis considered the association between partial/full/partial (combined) occupational stress models (the variable “exposure”) and job dissatisfaction (the variable “outcome”).

Results
Dissatisfaction rate was 26%. Full DCM and ERI models were better than partial ones to investigate job dissatisfaction. After adjustments, the combined models presented more robust measures of prevalence ratio than models evaluated separately (PR 2.93; CI 2.26–3.80).

Conclusions
The combination of models has shown greater capacity to identify situations of job dissatisfaction and provided more potential information to support actions for workers’ health.
Impact of Health-Related Quality of Life and Prediagnosis Risk of Major Depressive Disorder on Treatment Choice for Stage I Lung Cancer
Authors: van Dams Ritchell , Grogan Tristan , Lee Percy , Punglia Rinaa , Raldow Ann 
Published: September 2019

PURPOSE We hypothesized that prediagnosis depressive symptoms and patient-reported health-related quality of life (HRQOL) would be associated with treatment choice for stage I non–small-cell lung cancer (NSCLC). METHODS Using the SEER and Medicare Health Outcomes Survey (SEER-MHOS)–linked data set, we identified patients age 65 years and older with stage I NSCLC diagnosed between 2004 and 2013 who completed the HOS 24 or fewer months before diagnosis. HRQOL was measured by the Physical Component Summary (PCS) and Mental Component Summary (MCS) scores of the Medical Outcomes Study Short Form-36 and the Veterans RAND 12-Item Health Survey instruments. Major depressive disorder (MDD) risk was derived from responses to HOS questions that screen for depressive symptoms. Associations with treatment choice were assessed with multivariable multinomial logistic regression while controlling for prespecified patient characteristics. RESULTS We analyzed 515 evaluable patients, of whom 140 (27%) met criteria for risk of MDD. On univariable analysis, a higher proportion of patients who received radiotherapy (RT) versus surgery were at risk for MDD (34% v 22%, respectively; P = .011). On multivariable analysis, higher PCS and MCS scores were associated with a decreased likelihood of receiving RT compared with surgery (adjusted odds ratio per 10-point PCS increase, 0.60 [95% CI, 0.45 to 0.79; P < .001]; adjusted odds ratio per 10-point MCS increase, 0.61 [95% CI 0.46 to 0.80; P < .001]). CONCLUSION Among older patients with stage I NSCLC, there was a significant association between those who self-reported lower HRQOL and receipt of RT. There was also a nonsignificant association in MDD risk and increased likelihood of RT receipt. Additional studies are warranted to examine the impact of pretreatment HRQOL and MDD risk on clinical decision making.
Effect of abduction on avascular necrosis of the femoral epiphysis in patients with late-detected developmental dysplasia of the hip treated by closed reduction: A MRI study of 59 hips
Authors: Liu Y. H. , Xu H. W. , Li Y. Q. , Hong K. , Li J. C. , Pereira B. , Xun F. X. , Canavese F. 
Published: September 2019

Purpose The purpose of this study was to explore whether increasing the hip abduction angle would increase the incidence of avascular necrosis (AVN) in patients with late- detected developmental dysplasia of the hip (DDH) treated by closed reduction (CR) and spica cast immobilization. Methods A total of 55 patients (59 hips) with late-detected DDH underwent MRI after CR. Hip abduction angle and hip joint distance were measured on postoperative MRI transverse sections. The acetabular index and centre-edge angle were measured on plain radiographs at the last follow-up. The presence of AVN according to Kalamchi and McEwen's classification was assessed. We retrospectively analyzed the associations among abduction angles, hip joint distances, radiographic parameters, AVN and final outcomes, exploring the relationship between hip joint abduction angle and AVN rate. Results The mean age at the time of CR was 14.4 months SD 5.5 (6 to 28), and the mean follow-up was 26.2 months SD 8.1 (12.4 to 41.7). The mean hip abduction angle was 70.2° SD 7.2° (53° to 85°) on the dislocated side and 63.7° SD 8.8° (40° to 82°) on the normal side; the mean hip joint distance was 5.1 mm SD 1.9 (1.3 to 9.1) on the dislocated side and 2.2 mm SD 0.6 on the normal side (1.3 to 3.3). Eight of 59 hips (13.6%) developed AVN. Neither the amount of abduction nor hip joint distance increased the AVN rate (p = 0.97 and p = 0.65, respectively) or the dislocation rate (p = 0.38 and p = 0.14, respectively). Conclusion Abduction angle up to 70.2° following CR did not increase the AVN rate in children aged six to 28 months with late-detected DDH treated by CR. Level of evidence III.
Navigating the Publication Process: An ASABE Journals’ Perspective
Authors: Fox Garey A. , Douglas-Mankin Kyle R. , Muthukumarappan Kasiviswanathan , Zhu Jun , Walker Joseph C. 
Published: September 2019

Abstract. HighlightsASABE journals publish impactful research in multiple article types in addition to research articles. Prospective authors should consider a journal’s peer-review quality, readership, metrics, and page charges. An article’s impact should be measured based on citations instead of predicted based on the journal’s impact factor. Always recommend subject matter experts as reviewers so that a manuscript can benefit from their suggestions. Publishing in ASABE journals offers opportunities for contributing to and being recognized by the profession. Keywords: Impact factor, Page charges, Peer-reviewed journals, Review quality, Review time
Hubungan antara Tingkat Pengetahuan dan Sikap dengan Tindakan Pencegahan Penyakit Rabies pada Warga di Wilayah Puskesmas Kuta II
Authors: Sarjana Ni Kadek Ayu Septiani , Prasetyawati Arsita Eka , Budiani Dyah Ratna 
Published: September 2019

<p><strong><em>Introduction:</em></strong><em> </em><em>Rabies is a disease of animals (usually vertebrate) which is zoonotic (transmissible to humans). Rabies occurs in 24 out of the 34 provinces of Indonesia. Rabies is caused by a virus in the Family: Rhabdivoridae, Genus: Lyssavirus. Control the dog population and dog vaccination is effective and economical method to prevent the incidences of rabies in humans. This study aims to investigate the relationship between level of knowledge and attitude to the practice in prevention rabies infection in residents lived in area covered by Puskesmas Kuta II.</em><em></em></p><p><strong><em>Methods:</em></strong><em> </em><em>This study was a cross-sectional study and carried out by simple random sampling of 96 residents in the area of Puskesmas Kuta II. In this study, the independent variables are knowledge of and attitudes towards rabies disease while the dependent variable is the </em><em>practice </em><em>to prevent </em><em>rabies infection in human. Data were collected by a questionnaire-based interview. Analyses were then carried out using the chi-square (x<sup>2</sup>) followed by multivariate analysis using multiple logistic regressions.</em></p><p><strong><em>Results:</em></strong><em> </em><em>This study showed that knowledge has a significant relationship with </em><em>practice</em><em> for rabies disease prevention (p = 0.013; OR 4.240; 95% CI 1.352 up to 13.296). Attitude has a significant positive relationship with the value of p</em><em>ractice </em><em>for rabies disease prevention (p = 0.015; OR 3.073; 95% CI 1.233 up to 7.627). The combined effect of knowledge and attitudes to pr</em><em>actice </em><em>for rabies prevention were approximately 20.90% (Negerkerke R square = 0.209).</em></p><p><strong><em>Conclusions:</em></strong><em> </em><em>There was a significant relationship between knowledge and attitudes with the </em><em>practice </em><em>for rabies disease prevention in residents in the area of Puskesmas Kuta II, the higher level of knowledge and improved attitudes will improve </em><em>practice for</em><em> rabies disease prevention amongst residents in the area of Puskesmas Kuta II.</em></p><p><em> </em></p><p><strong><em>Key words</em></strong><em>: </em><em>Rabies; Rabies; Preventio; Knowledge; Attitude; Practice</em><em></em></p>
Potensi Scopoletin sebagai Agonis Reseptor Transferin 2 untuk Pengembangan Terapi Anemia Defisiensi Besi
Authors: Paramanindita Asti Swari , Indarto Dono , Balgis Balgis 
Published: September 2019

<p><strong>Introduction</strong>: Iron Deficiency Anemia (IDA) is caused by imbalance between iron intake and iron loss in blood circulation. Increased hepcidin level plays an important role in the etiology of IDA. Normally, expression of hepcidin protein is controlled by three different pathways, one of them is interaction between holo Transferin (Holo-Tf) and Transferrin Receptor 2 (TfR-2). Recently, Indonesian herbal plants have widely been used as herbal medicine but there is no active compound that can activate TfR-2 for IDA therapy. The aim of this study was to explore phytochemicals derived from Indonesian herbal plants to interact with TfR-2.</p><p><strong>Methods: </strong>The study was a bioinformatics study with a molecular docking method. The SWISS-MODEL software was used to make TfR-2 protein modeling because the molecular structure of TfR-2 remains unknown. Holo-Tf was used as a standard ligand and obtained from Protein Data Bank with PDB ID 1SUV. All Indonesian phytochemicals which (1) registered at HerbalDB (2) had a three-dimensional molecular structure at PubChem (3) met Lipinski’s Rule of Five criteria were used in this study. AutoDock Vina 1.1.2 was used to analyze the binding affinity which was in kcal/mol. Phytochemical-TfR-2 binding complexes were visualized by using Chimera 1.10rc and or Pymol 1.7.</p><p><strong>Result: </strong>The docking scores of holo-Tf modification with TfR-2 were -6,4±0,1 kcal/mol at Arg466 and -3,4±0,1 kcal/mol at Arg689 respectively. Interaction of modification holo-Tf and TfR-2 was observed not only at Arg466 and Arg689 but also with Asp642 and Ile682. Docking scores of scopoletin were -7,1±0,1 kcal/mol at Arg466 and -5,4±0,1 kcal/mol at Arg689. Scopoletin could interact with TfR-2 at Arg466, Arg689, and Leu630 residues.</p><p><strong>Conclusions: </strong>Computationally, scopoletin is a potential TfR-2 agonist. In future studies, in vitro assay will be used to evaluate the agonist effect of scopoletin in TfR-2.</p><p> </p>
Особенности массопереноса при ионной имплантации
Authors: Абылкалыкова Риза Батырхановна , Квеглис Людмила Иосифовна , Рахадилов Бауржан Корабаевич , Бектасова Гульсум Сафуановна 
Published: September 2019

Исследованы продукты реакции, полученные при ионной имплантации азота, кислорода и фосфора в вольфрамовую мишень. Выяснены условия создания новых соединений при высокодозной имплантации, приводящей к процессам быстрого массопереноса ионов в материал мишени. Установлено, что ионная имплантация азота в вольфрам приводит к возникновению фазы внедрения W2N с ГЦК-структурой; имплантация кислорода — к образованию фазы с плотноупакованной ГЦК-структурой, близкой по структуре и параметрам к W20; фосфора — к образованию фосфида вольфрама W2P с орторомбической структурой после дополнительного отжига при температурах, превышающих 800-900 0С. Сделана оценка локального давления потока ионов на поверхность мишени, которое приводит к локальному искривлению кристаллической решетки, благодаря чему возможен быстрый массоперенос имплантированных ионов в материале мишени.
Образование фаз внедрения при ионной имплантации является результатом локализации сдвиговой деформации в условиях ускоренного массопереноса. В условиях высокодозной ионной имплантации формируются высоконеравновесные пересыщенные твердые растворы, а также высокодефектные структурно-неравновесные состояния с высокой кривизной кристаллической решетки.
Primer caso de endocarditis por Abiotrophia defectiva en paciente adulto con coartación aórtica en hospital de Santa Fe
Authors: Valletto Mónica Beatriz , Mollerach Analía Susana , Nagel Alicia , Manias Valeria , Nardín María Elena , Mendosa Maria Alejandra , Morano Susana Teresita , Ramos Claudia Fabiana , Méndez Emilce De los Angeles , Nepote Andrea , Vay Carlos 
Published: September 2019

Abiotrophia defectiva, previamente conocida como variante nutricional de estreptococos forma parte de la microbiota normal de la cavidad oral, urogenital y tracto gastrointestinal. Se asocia con infecciones severas como bacteriemia, endocarditis, abscesos cerebrales, osteomielitis, artritis séptica y queratopatía del cristalino. Es un microorganismo difícil de diagnosticar y las tasas de morbimortalidad, son altas.Se presenta el caso de un paciente adulto joven con coartación aórtica, con antecedentes de miocardio no compacto y comunicación ventricular pequeña, que consulta por cuadro de 16 días de evolución, caracterizado por dolor en la región glútea y fiebre.Se solicitan tres muestras de hemocultivos que se procesaron por método automatizado BACTEC (Phoenix). Las tres muestras de hemocultivos resultaron positivas a las 48 h para cocobacilos grampositivos en cadena. La identificación del aislamiento se realizó con autoanalizador BD PhoenixTM System dando como resultado Abiotrophia/Granulicatella, confirmándose por espectrometría de masas (MALDI-TOF) como Abiotrophia defectiva.Se realizó tratamiento antibiótico inicial con ampicilina, gentamicina y vancomicina por 7 días, continuando con ceftriaxona más gentamicina durante 22 días, evolucionando favorablemente.Debido a este hallazgo es importante alertar a los infectólogos y microbiólogos, considerar a Abiotrophia defectiva como posible agente causal de endocarditis.
RESÚMENES DE TESIS: DOCTORADO EN EDUCACIÓN EN CIENCIAS EXPERIMENTALES
Authors: Vignatti Maria Del Carmen 
Published: September 2019

Diseño y desarrollo de un Laboratorio Remoto para la enseñanza de la física en la UNED de Costa RicaCarlos Alberto Arguedas Matarrita
Profesores de física de la Mesoregión de Bahía. Aspectos históricos, formación y trabajo docenteFerdinand Martins Da Silva
CHALLENGING POTENCY OF JAYENGAN : NEW OPPORTUNITY FOR DEVELOPMENT OF SUSTAINABLE JEWELRY CREATIVE INDUSTRIAL KAMPUNG-BASED TOURISM IN SURAKARTA
Authors: Astuti Winny 
Published: September 2019

Local-based tourism becomes one of economic development strategies of the area based on local potency. Sustainable tourism can be defined as ‘tourism, which takes into account of its current and future economic, social and environmental impacts’, addressing the demands of visitors, the environment, the industry and local communities as the host of development. KampungJayengan Surakarta is the traditional settlements located in the downtown, which spontaneously developed by Banjar Community, that arrived in Surakarta in 1746 as jewelry traders. Right now, the existence and the identity of Kampung Jayengan as Kampung of Jewelry has been lost its attraction, constrained by development of modern public facilities and services in the city center. This study analyzed the challenge faced by Kampung Jayengan to develop its potencies as Jewelry Industrial Kampung-based Tourism becoming a part of tourist destination in Surakarta as a creative city. The research type was predictive research using mixed methods. Several analysis have been conducted from identification of the potencies of kampung. It consisted of analysis comformity of the area to the spatial structure general plan policy; analysis of demographic; analysis of economy, analysis of availability of public infrastructure; analysis of building and environment and analysis of land use suitability. Results of analysis shows that the area has a great challenge for Jewelry Industrial Kampung-based Tourism development, which will have multiplier effect on increasing economic development of the area as well as economic development and welfare of the local community
MERKEZ BANKASI BAĞIMSIZLIĞI VE MALİ GÜVEN İLİŞKİSİ: MIST ÜLKELERİ PANEL VERİ UYGULAMASI
Authors: EREK Mustafa Salim 
Published: September 2019

Temel görevi fiyat
istikrarını sağlamak ve sürekli kılmak olan merkez bankaları için, özerklik
veya bağımsızlık günümüzde neredeyse tüm dünyada yerleşik bir standart haline
gelmiştir. 2008’deki küresel krizi takiben merkez bankalarına finansal
istikrarı korumanın da ilave bir görev olarak yüklenmesiyle bağımsızlık
sorgulanmaya başlanmıştır. Bu bağlamda merkez bankası bağımsızlığı ile mali güvenilirlik
veya kredibilite arasındaki ilişkinin önemli bir araştırma konusu haline
geldiği görülmektedir.Çalışmamızda MIST ülkeleri olan Meksika, Endonezya, Güney
Kore ve Türkiye’nin merkez bankası bağımsızlığı ile beraber çeşitli ekonomik
göstergelerinin sistemin mali güvenilirliği’ne katkıda bulunup bulunmadığı
incelenecektir. Analizler, Doğrusal (Sabit Etkiler ve Rassal Etkiler) Panel Veri Yöntemi vasıtasıyla yürütülecektir.
FACTORS CAUSING CHANGE IN FOREIGN EXCHANGE DEPOSITS IN AN EMERGING ECONOMY: TURKEY CASE
Authors: SÖNMEZER Sıtkı , ÇELİK İsmail Erkan 
Published: September 2019

Financial dollarization has increased substantially in
emerging markets in recent years. A material increase in financial
dollarization may concern policy makers but it also serves as a cushion for
banks and the states. Increase in foreign Exchange deposits may arise from the
need to preserve purchasing power, speculation or liquidity concerns. This
paper aims to shed light to the relation between foreign exchange deposits and
factors such as sight FX deposits, USD/TRY parity, CPI, confidence ındex, VIX,
TL deposits, dollar index via a VECM model. Sight FX deposits are found to be a
positive and a statistically significant influencing factor on FX deposits;
whereas, confidence index and CPI have a negative but a significant relation with
FX deposits. Factors that have an influence on the increase in foreign Exchange
deposits shall be closely monitored to mitigate the adverse effects of it.&nbsp;