bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reducing cancer health disparities among US Latinos: a Freireian approach
Authors: Rivera Yonaira M. 
Published: June 2018

PurposeThe purpose of this paper is to apply Paulo Freire’s writings from Pedagogy of the Oppressed to critique current efforts to reduce cancer health disparities (CHDs) among Latinos in the USA.Design/methodology/approachFreire’s writings on oppression, critical consciousness, praxis and dialogical education are applied to recent efforts to reduce CHDs among Latinos in the USA through the use of promotores.FindingsFreireian teachings can provide insight on ways to engage Latino communities in culturally sensitive conversations that respect deeply rooted beliefs, and address the political and socioeconomic inequities many continue to face. Programs must revisit Freire’s political and transformative roots to ensure efforts to reduce CHDs also promote health equity and community empowerment.Practical implicationsPublic health initiatives should incorporate Freireian principles of dialogical education and critical consciousness in the development of cancer prevention and screening programs tailored to Latinos in the USA to ensure program longevity and success.Social implicationsApproaching conversations and interactions dialogically can foster critical engagement and empower collective action among Latino communities in efforts to improve their environments and reduce health disparities.Originality/valueThis is a multi-layered analysis of different social and structural factors influencing CHDs among Latinos in the USA, and is coupled with a historical overview of colonialism and oppression in Latin America. It culminates in suggestions on ways to improve future public health efforts that embrace Freireian approaches and promote health equity.
Effect of electromagnetic field on tribological properties of two lubricating oils containing zinc dithiophosphate
Authors: Jiang Zeqi , Fang Jianhua , Chen Fei , Chen Boshui , Gu Kecheng 
Published: June 2018

Purpose
This paper aims at understanding tribological properties of lubricating oils doped with zinc dithiophosphate(ZDDP) with and without electromagnetic field impact.

Design/methodology/approach
The friction and wear properties of the oils formulated with zinc butyloctyl dithiophosphate (T202) or zinc dioctyl dithiophosphate (T203) under electromagnetic field or nonelectromagnetic field were evaluated on a modified four-ball tribotester. The characteristics of the worn surfaces obtained from electromagnetic or nonelectromagnetic field conditions were analyzed by scanning electronic microscopy, energy dispersive spectrometer and X-ray photoelectron spectroscopy. This paper focuses on understanding influence of electromagnetic field on lubrication effect of the ZDDP-formulated oils.

Findings
The electromagnetic field could effectively facilitate anti-wear and friction-reducing properties of the oils doped with T202 or T203 as compared to those without electromagnetism affection, and the T203-doped oils were more susceptible to the electromagnetic field. The improvement of anti-wear and friction-reducing abilities of the tested oils were mainly attributed to the promoted tribochemical reactions and the modification of the worn surfaces (forming Zn-Fe solid solution) induced by the electromagnetic field.

Originality/value
This paper has revealed that tribological performances of ZDDP-doped oils could be improved by the electromagnetic field and discussed its lubrication mechanisms. Investigating tribological properties of additives from the viewpoint of electromagnetics is a new attempt, which has significance not only for the choose and designing of additives in electromagnetic condition but also for development of tribological theories and practices.
Critical factors for enhancing green service innovation
Authors: Lin Yu-Hsien , Chen Hsin-Chung 
Published: June 2018

Purpose
The purpose of this study is to examine the influences of green entrepreneurial orientation (GEO) and green relationship quality (GRQ) on green service innovation (GSI).

Design/methodology/approach
The authors mailed 1,898 questionnaires to the sampled companies. Ultimately, 207 companies participated in the authors’ study. This resulted in a valid sample of 542 hotel managers.

Findings
The research results indicate that GEO improves GRQ and GSI. Furthermore, GRQ positively affects GSI and mediates the relationship between GEO and GSI.

Research limitations/implications
The authors’ study enhances the quality of nature and highlights the mediation role of GRQ.

Practical implications
Firms can create and establish GRQ to enhance their GSI.

Social implications
The authors’ study shows that environmentally friendly firms can enhance natural locations and conditions of natural resources.

Originality/value
This study aims to develop a context-specific model of GEO for hospitality managers.

研究目的
本论文旨在研究绿色创业倾向和绿色关系质量对于绿色服务创新的影响。

研究设计/方法/途径
本论文采用邮寄问卷采样形式, 向采样公司共寄出1898份问卷。最终, 207家公司参与本研究项目。有效样本数量为542份来自酒店经理人的问卷。

研究结果
绿色创业倾向对于绿色关系质量和绿色服务创新有着促进作用。此外, 绿色关系质量积极地影响绿色服务创新, 并且对于绿色创业倾向和绿色服务创新有着中间变量的作用。

研究理论限制/意义
本论文对提高自然质量有着促进作用, 并且着重说明了绿色关系质量的中间调解作用。

研究实践意义
公司能够通过创造和建立绿色关系质量的手段来提高他们的绿色服务创新。

研究原创性/价值
本论文以特定背景为基础, 建立了一个针对酒店经理人的绿色创业倾向的模型.
Perspectives of directors of civilian oversight of law enforcement agencies
Authors: Rosenthal Richard A. 
Published: June 2018

Purpose
The purpose of this paper is to involve interviews with civilian oversight of law enforcement (COLE) directors from throughout the USA with the purpose of obtaining their perspectives on what it takes to create and sustain successful COLE programs.

Design/methodology/approach
The project involved 24 semi-structured interviews with experienced COLE directors. The interviews were transcribed and coded and this paper presents these perspectives according to patterns identified during analysis.

Findings
The research identified themes and patterns in the attitudes of the oversight directors which included numerous conditions necessary for success of an oversight agency. Amongst the most important conditions included agency independence, director job security, the need for professional qualified staff, unfettered access to information, the ability to publicly report on the agency’s work and a willingness on the part of government officials to tolerate criticism of the police.

Originality/value
This is the first study to identify the challenges and impediments to sustainable COLE mechanisms from the point-of-view of experienced agency directors. The findings can be used by future practitioners to learn from past experiences.
The role of tourist gastronomy experiences in regional tourism in Russia
Authors: Bukharov Igor , Berezka Svetlana 
Published: June 2018

Purpose
This paper aims to highlight the role of tourist gastronomy experiences and the possible contribution of the local gastronomy to a tourist destination’s attractiveness and competitiveness.

Design/methodology/approach
The paper proposes a conceptual framework for understanding the role of local gastronomy in destination attractiveness and competitiveness. It is based on an analysis of a case study of Russian experiences in developing a gastronomy value proposition for tourists.

Findings
The paper indicates the potential for a gastronomy value proposition, as this is important to tourists and it makes a positive contribution to destination’s attractiveness. The paper also reveals some challenges in the Russian hospitality market from a gastronomy perspective.

Practical implications
Several recommendations are presented in support of the creation of a gastronomy value proposition based on regional culinary heritage and local food products specifics.

Originality/value
The paper provides insights on the role of a given destination’s gastronomy in tourism development in Russia. The study also contributes to the literature on emerging markets by providing an overview of the main challenges for gastronomy in the Russian hospitality market.
MicroRNA‐645 promotes metastasis of osteosarcoma via targeting tumor suppressor NM23 nucleoside diphosphate kinase 2
Authors: Jiao Guang‐Jun , Zhang Shi‐Jun , Li Yi , Wu Wen‐Liang , Liu Hai‐Chun 
Published: June 2018

SummaryOsteosarcoma is the most common non‐hematological primary bony malignancy in children and young adults with tumor metastasis being a common event at diagnosis. Understanding the pathogenesis of metastatic osteosarcoma may help identify potential therapeutic targets. In this study, we found that the level of microRNA‐645 (miR‐645) in osteosarcoma tumor tissues was significantly increased compared with their paired non‐tumorous tissues, and was associated with histologic grade, TNM staging, lymph metastasis and distant metastasis. Knockdown of miR‐645 caused a remarkable inhibition of migration of osteosarcoma U2OS cells. Furthermore, miR‐645 inhibited NME2 (nucleoside diphosphate kinase 2) expression through directly binding to its 3′ untranslated region. In human osteosarcoma tissues, we also found that NME2 was significantly decreased in tumor tissues, and its level was negatively correlated with miR‐645. In addition, silencing NME2 attenuated the decreased cell migration by knockdown of miR‐645, suggesting that it was involved in the miR‐645 induced cell migration of osteosarcoma cells. Taken together, we found that miR‐645 was up‐regulated in osteosarcoma tissues and could promote osteosarcoma cell migration through directly inhibiting the tumor suppressor NME2. Our data provide novel insight into the role of miR‐645 in osteosarcoma and indicate that miR‐645 might be a potential therapeutic target of osteosarcoma.
Devolution and Parliamentary Representation: The Case of the Scotland and Wales Bill, 1976–7
Authors: Evans Adam 
Published: June 2018

AbstractFor as long as devolution has been debated in the UK, there has been fierce discussion as to the representation of the would‐be affected areas at Westminster. That this has been the case is a consequence of Westminster's dual remit as both a state‐wide and a sub‐state legislature. While this dual remit was relatively straightforward when applied to all nations of the UK, it does, however, raise serious questions about the equality of MPs at Westminster in the face of asymmetric devolution that would carve out parliament's remit in some, but not all, parts of the UK. These questions bedevilled Gladstone's Irish Home Rule Bills in the late 19th century and have been a recurrent feature of debate following New Labour's devolution programme in the late 1990s, culminating in the adoption of a system of ‘English Votes for English Laws’ by the house of commons in October 2015. This article looks at this issue through the lens of the ill‐fated Scotland and Wales Bill introduced by the Callaghan government in 1976. It explores the roots of the bill and how, and why, the idea of referring the question of territorial representation, post‐devolution, to a Speaker's conference, came to secure the initial support of cabinet as the best answer to this problem, and why the government swiftly changed its mind. Parliamentary statecraft considerations served to push a Speaker's conference onto the institutional agenda, before ultimately dooming it to failure.
Stage T3b prostate cancer diagnosed by seminal vesicle biopsy and treated with neoadjuvant hormone therapy, permanent brachytherapy and external beam radiotherapy
Authors: Stone Nelson N. , Stock Richard G. 
Published: June 2018

ObjectivesTo report the long‐term results of prostate brachytherapy followed by external beam radiotherapy (EBRT) in men with a positive seminal vesicle biopsy (+SVB).Patients and MethodsIn all, 1081 men with localised prostate cancer were treated with permanent brachytherapy, of which 615 had staging SVB and 53 (9.4%) were positive. Higher stage, Gleason score and PSA level were associated with a +SVB (P < 0.001). Patients with +SVB and negative laparoscopic pelvic lymph node dissection, bone and CT scans had 3 months of androgen‐deprivation therapy (ADT) followed by 103Pd implant to the prostate (dose 100 Gy) and proximal SVs, and 2 months later 45 Gy EBRT. ADT was continued for a median of 6 months (total ADT 9 months). The mean (range) follow‐up was 9 (5–22) years.ResultsBiochemical freedom from failure (computed by the Phoenix definition), freedom from metastasis, and cause‐specific survival (CSS) for patients with a negative SVB (–SVB) vs +SVB at 15 years, was 76.3% vs 60.6% (P = 0.001), 95.4% vs 78.2% (P < 0.001), and 95% vs 70.4% (P < 0.001), respectively. Prostate cancer death occurred in 45 of 590 (7.6%) men with a –SVB vs eight of 25 (32%) with a +SVB (odds ratio 5.7, 95% confidence interval 2.35–13.9, P < 0.001). Cox proportion hazard rates (HRs) demonstrated Gleason score (P < 0.001, HR 1.9), stage (P = 0.010, HR 1.42), RT dose (P = 0.013, HR 0.991), and +SVB (P = 0.001, HR 4.48), as significantly associated with CSS.ConclusionsMen with a +SVB have inferior CSS compared to those with a −SVB. However, a strategy that included a SVB in high‐risk patients and implantation of the SVs in men undergoing combined therapy still yields favourable long‐term results.
Changes in perceived oral health in a longitudinal population‐based study
Authors: Torppa‐Saarinen Eeva , Tolvanen Mimmi , Suominen Anna L. , Lahti Satu 
Published: June 2018

AbstractObjectivesThe aim was to examine whether the changes in different measures of perceived oral health (POH) were similar and related to each other over 11 years in the Finnish adult population in a longitudinal setting. Perceived oral health was measured by means of subjective oral health (SOH), self‐assessed treatment need (STN), and oral health‐related quality of life (OHRQoL).MethodsThe data were collected as part of the nationally representative Health 2000 and Health 2011 (BRIF 8901) surveys on Finnish adults born in 1981 or earlier. SOH and STN were measured using single items and OHRQoL using the 14‐item Oral Health Impact Profile (OHIP‐14). The changes in STN and OHRQoL were reported by age group and by gender. Age groups (born in 1971 or later, in 1956‐1970, in 1946‐1955, or in 1945 or earlier) were based on access to subsidized oral health care. General linear mixed models for changes in perceived oral health variables were conducted.ResultsSubjective oral health and oral health‐related quality of life with impacts occurring occasionally, fairly often, or very often (OFoVo) showed similar results and remained good or improved in the majority of the participants. Self‐assessed treatment need in the population showed less consistent results. Subjective oral health was good in the adult population. About half of the participants, regardless of age and gender, reported self‐assessed treatment need in both years, showing a decrease among women and an increase in the youngest group. Perceived oral health improved significantly in the two oldest age groups regardless of the measure. The general linear mixed model revealed that changes in all three perceived oral health variables were related even when adjusted for age and gender.ConclusionMultiple perceived oral health measures might be useful for service planning, as the changes in the three separate measures used in this longitudinal study were various and thus measured different aspects of perceived oral health. Research including both self‐perceived and clinical indicators is needed to understand need for care as a whole.
Nonsyndromic orofacial clefts among Jews and non‐Jews born in 13 hospitals in Israel during 1993‐2005
Authors: Shapira Yehoshua , Blum Itay , Haklai Ziona , Shpack Nir , Amitai Yona 
Published: June 2018

AbstractObjectivesOrofacial clefts are one of the most common birth malformations and represent a significant public health economic expenditure. The purpose of this investigation was to study the epidemiology of orofacial clefts in newborns from 1993 to 2005 in Israel. In addition, a comparison of data from the National Birth Defects Registry (NBDR) and Hospital records will be made.MethodsA retrospective data review of reports to the Israeli NBDR on infants with orofacial clefts in comparison with records reviewed at 13 major hospitals, accounting for 60% of all births in Israel.ResultsOf 1334 newborns found to be with orofacial clefts all over Israel between 1993 and 2005, 1015 were reported to the NBDR and 319 were unreported but retrieved from hospital files. During this period, of the 976 578 live births found in the 13 participating hospitals, there were 866 newborns with orofacial clefts. Of those, 684 (79%) were nonsyndromic orofacial clefts and 182 (21%) had additional syndromes. The prevalence of nonsyndromic orofacial clefts was 7/10 000 live births, lower than reported outside Israel. Only 65% of orofacial clefts retrieved from the 13 hospitals were reported to the NBDR. A significantly higher orofacial cleft prevalence was found among non‐Jews than Jews (11 and 6 of 10 000 live births, respectively), (P< .00 001). CL/P was found more frequently than isolated cleft palate (CP). More males had orofacial clefts than females, mostly unilateral with left side predominance.ConclusionsThe prevalence of nonsyndromic orofacial clefts was found to be 7/10 000 live births. The higher orofacial cleft prevalence among non‐Jews may be explained by the high prevalence of consanguinity and deprived maternal nutritional status in this population.
Threshold‐stimulated kallikrein activity distinguishes bradykinin‐ from histamine‐mediated angioedema
Authors: Lara‐Marquez Maria L. , Christiansen Sandra C. , Riedl Marc A. , Herschbach Jack , Zuraw Bruce L. 
Published: June 2018

SummaryBackgroundThe lack of specific biomarkers makes the diagnosis of hereditary angioedema (HAE) with normal levels of C1‐inhibitor (C1INH) protein (HAE‐nl‐C1INH) and idiopathic non‐histaminergic angioedema (INHA) difficult. Confirming or excluding these diagnoses is a significant challenge for clinicians evaluating patients with angioedema.ObjectiveTo develop a reliable biomarker that would aid the diagnosis of HAE‐nl‐C1INH and INHA.MethodsA total of 154 consecutive patients referred for angioedema at a single centre were enrolled and evaluated. Subjects were clinically phenotyped based on clinical history and response to treatment by clinicians blinded to laboratory assay results. Plasma kallikrein activity was measured by the cleavage of the fluorometric substrate Z‐Phe‐Arg‐AMC‐HCL in plasma samples stimulated ex vivo with submaximal doses of dextran sulphate.ResultsStimulated plasma kallikrein activity (mean relative fluorescence units/min ± SD) was significantly increased in both HAE‐nl‐C1INH (1804 ± 600) and INHA (1579 ± 371) subjects compared to non‐swelling controls (171 ± 46) and histaminergic angioedema (133 ± 30) subjects. Using a threshold cut‐off based on the normal controls, HAE‐nl‐C1INH and INHA subjects could be differentiated from histaminergic angioedema subjects with high sensitivity (negative predictive value 86%‐89%) and specificity (positive predictive value 80%‐100%).Conclusion and Clinical RelevanceThe stimulated kallikrein activity assay allows differentiation of bradykinin‐ from histamine‐mediated angioedema. The assay could feasibly be considered as a potential clinical tool for the diagnosis of bradykinin‐mediated angioedema.
An online self‐test added to colorectal cancer screening can increase the effectiveness of familial cancer risk assessment without increasing distress
Authors: van Erkelens A. , Sie A. S. , Spanier M. B. W. , van Kouwen M. , Visser A. , Prins J. B. , Hoogerbrugge N. 
Published: June 2018

AbstractAimMost people who are at increased familial colorectal cancer (FCRC) risk are not identified, despite the need for enhanced surveillance colonoscopy for effective CRC prevention. An online self‐test may enhance this identification. We assessed whether taking an online self‐test to identify increased FCRC risk increases anxiety, distress or CRC risk perception in population‐based CRC screening.MethodAfter the precolonoscopy consultation, patients who had a positive immunohistochemical occult faecal blood test (iFOBT+) in population‐based CRC screening were invited by email to take an online self‐test at home which returned details of family history. Anxiety (STAI‐DY), distress (HADS) and CRC risk perception were assessed immediately before and after taking the online self‐test and 2 weeks later.ResultsOf 250 participants invited, 177 (71%) completed the online self‐test and psychological questionnaires and 153 (61%) completed questionnaires 2 weeks later. The median age was 65 years (range 61–75). The FCRC risk was increased in 17 participants (9.6%). Of these, 12 (6.8%) had a highly increased FCRC risk and may benefit from germline genetic testing for Lynch syndrome. In 7 of 17 participants (40%) the self‐test obtained novel information on family history. Anxiety and distress levels were, and remained, below a clinically relevant level. Perception of CRC risk remained unchanged. Most participants (83%) would recommend the online self‐test to others.ConclusionOf those with a iFOBT+, 9.6% had a previously unidentified increasedFCRC risk and require an enhanced surveillance colonoscopy instead of iFOBT. As screening for this risk did not increase anxiety or distress, and was highly acceptable, we recommend adding the online self‐test to population‐based CRC screening.
Perirenal fat surface area as a risk factor for perioperative difficulties and 30‐day postoperative complications in elective colon cancer surgery
Authors: der Hagopian O. , Dahlberg M. , Heinius G. , Nordberg J. , Gustafsson J. , Nordenvall C. , Sandblom G. , Farahnak P. , Everhov Å. H. 
Published: June 2018

AbstractAimVisceral obesity is associated with perioperative and postoperative complications in colorectal surgery. We aimed to investigate the association between the perirenal fat surface area (PRF) and postoperative complications.MethodData on 610 patients undergoing curative, elective colon cancer resection between 2006 and 2016 at Stockholm South General Hospital were retrieved from a local quality register. We assessed perioperative and postoperative outcomes using a multinomial regression model adjusted for age, sex, American Society of Anesthesiologists classification and surgical approach (open/laparoscopy) in relation to PRF.ResultsPRF could be measured in 605 patients; the median area was 24 cm2. Patients with PRF ≥ 40 cm2 had longer operation time (median 223 vs 184 min), more intra‐operative bleeding (250 vs 125 ml), reoperations (11% vs 6%), surgical complications (27% vs 13%) and nonsurgical infectious complications (16% vs 9%) than patients with PRF < 40 cm2, but there were no differences in the need for intensive care or duration of hospital stay. The multivariate analyses revealed an increased risk of any complication [OR 1.68 (95% CI 1.1–2.6)], which was even more pronounced for moderate complications [Clavien–Dindo II, OR 2.14 (CI 1.2–2.4]; Clavien–Dindo III, OR 2.35 (CI 1.0–5.5)] in patients with PRF ≥ 40 vs < 40 cm2. The absolute risk of complications was similar in men and women with PRF ≥ 40 cm2.ConclusionPRF, an easily measured indirect marker of visceral obesity, was associated with overall and moderate complications in men and women and could serve as a useful tool in the assessment of preoperative risk.