bluuebunny/crossref_metadata_2025_split huggingface dataset:
P099 Comparative frequency of Clostridial infection in patients with ulcerative colitis receiving mesenchymal stromal cells and biological preparations
Authors: Oleg Knyazev , Anna Kagramanova , Albina Lishchinskaya , Marina Chernova , Asfold Parfenov 
Published: July 2019

BACKGROUND:
Patients with inflammatory bowel disease (IBD) experienced more frequent development of Clostridial infection and much higher rates of morbidity and mortality compared to patients without IBD. Risk factors are immunosuppressive therapy.

METHODS:
The aim is to compare the frequency of Clostridial infection (CI) in patients with ulcerative colitis (UC) receiving bone marrow mesenchymal stromal cells (MSC) and biological therapy.

MATERIALS AND METHODS:
The patients were divided into 3 groups: the first group (n = 23) received the MSCs culture according to the scheme (0-1-2 weeks, then every 26 weeks); the second group of patients with UC (n = 21) received infliximab (IFX) in combination with azathioprine (AZA) according to the recommended scheme, the third group received only IFX according to the scheme. The toxins A and B of Clostridium difficile were determined by the enzyme immunoassay in the stool. The comparative analysis was carried out using the method of 4-field tables using nonparametric statistical criteria.

RESULTS:
In patients of the 1-st group, toxin A was detected in 1/23 patients (4.3%), in the 2-nd group - in 2/21 (9.5%) (RR 0.45, 95% CI 0.04–4.6, χ2 0.46, P > 0.05), in the third - in 2/18 (11.1%) (RR 0.4, 95% CI 0.04–3.98, χ2 0.7, P > 0.05). In patients of the 1-st group, toxin B was detected in 2/23 patients (8.6%), in the second group in 3/21 (14.3%) patients (RR 0.6, 95% CI 0.1–3.3, χ2 0.3, P > 0.05), in the third - in 2/18 (11.1%) (RR 0.8, 95% CI 0.12–5, 03; χ2 0.07; P > 0.05). In patients of the 1-st group toxins A and B were not detected - 0/23 (0.0%), in the 2-nd group toxins A and B were detected in 7/21 (33.3%) patients (χ2 9.5, P < 0.05), in the third - in 5/18 (27.8%) (χ2 7.3, P < 0.05). Totally in patients of the 1-st group, Clostridium difficile toxin A and B was detected in 3/23 patients (13.1%), in the second group - in 12/21 (57.1%) patients with UC (RR 0.23, 95% CI 0.075–0.7, χ2 9.5, P < 0.05), in the third - in 9/18 (50.0%) (RR 0.26, 95% CI 0.08–0.82, χ2 6.6, P < 0.05).

CONCLUSION(S):
The frequency of Clostridial infection in patients with ulcerative colitis receiving mesenchymal stromal cells is significantly lower than in patients with ulcerative colitis receiving biological immunosuppressive preparations.
P100  Study of endoscopic findings in children with chronic diarrhea attending Alexandria university children's hospital
Authors: Rasha Metwally 
Published: July 2019

BACKGROUND:
Chronic diarrhea is a major problem worldwide with high morbidity and mortality.

METHODS:
The medical records were revised for: clinical presentation, clinical examination, laboratory investigation and endoscopic findings

RESULTS:
Forty patients were included in the study. The mean age of the patients was 3 and half years. Patients from rural areas were more than from urban regions. Sixty-five percent of the patients were males and thirty-five percent were females. Mucoid diarrhea was the most common type of diarrhea. Failure to thrive was evident in abetalipoproteinemia and Crohn's patients. Fecal calprotectin above 150 mg/kg is highly specific and sensitive for inflammatory bowel disease. Eosinophilic enterocolitis was the most common disease (57.5%) followed by celiac disease (15%) then ulcerative colitis (12.5%).

CONCLUSION(S):
Management of patients with chronic diarrhea should be initiated and followed in a specialized Pediatric GIT unit since it requires experience and close clinical, endoscopic and pathological assessment.
P106 Small bowel adenocarcinoma in the setting of Crohn's disease: systematic review of the literature
Authors: Hande Aydinli H. , Feza Remzi , Justin Ream , Antonio L. Galvao Neto , Alec J. Megibow , Leon Pachter H. 
Published: July 2019

BACKGROUND:
Small bowel cancer (SBC) is a rare entity that can be associated with Crohn's Disease. The incidence of SBC in patients with CD is increased by 18.75-fold compared to normal population. The pathogenesis of SBC in the setting of CD is not fully understood, but the disease has a poor prognosis due to diagnostic challenges associated with the primary disease. The aim of this study is to present 2 cases treated within a year in a high volume IBD center and to conduct a systematic literature review of small bowel adenocarcinoma (SBA) associated with small bowel CD.

METHODS:
Systematic literature review was done by using MEDLINE and EMBASE databases and data regarding demographics, presentation, diagnosis, treatment and survival were extracted. Articles that did not clearly state the location of the Crohn's disease and type of the cancer were excluded.

RESULTS:
We identified 216 patients diagnosed with small bowel adenocarcinoma in the setting of small bowel Crohn's disease from 117 studies. In this review obstruction was the most common initial symptom (n = 82, 59%; data are missing in 77 patients). Other common symptoms were abdominal pain (n = 12), anemia-bleeding (n = 11), diarrhea (n = 10), and fistulas (n = 5). there were 206 patients with one adenocarcinoma and 10 patients with 2 different adenocarcinomas. Among the patients with only one tumor, 154 patients (74.7%) were found to have ileal SBA. The median time to diagnosis of SBA from the diagnosis of CD was 18 months (1-300 months, data on 10 patients were missing). Out of 129, 64 patients (49.6%) were diagnosed with cancer after the surgical procedure whereas 46 patients (35.6%) were diagnosed intraoperatively and 15 (11.6%) were diagnosed preoperatively. Four patients (3.2%) were diagnosed at the autopsy without any surgical interventions and data were missing in 87 patients. 36.7% (18/49 patients) of the patients operated for obstruction were alive at one year, and 15.2% (7/46 patients) at 2-year. Although these percentages are lower than other studies reported in the literature, data was missing in 34 patients, so this might have affected the outcomes.

CONCLUSION(S):
Small bowel adenocarcinoma should be in the differential diagnosis in patients with longstanding ileal Crohn's disease presenting with small bowel obstruction, anemia, and perforation. Diagnosis and management of the small bowel adenocarcinoma in the setting of Crohn's disease is challenging and awareness and early diagnosis may avoid mortality.
Postbariatric Surgery Hyperammonemia: A Rare Cause of Encephalopathy
Authors: Castineira Janyll , Goltser Yevgeniya , Vila Mark , Patel Reepal , Croix Peggy St. , Ashe Duane , Al-Andary Salah , Halleman Christopher , Alkurdi Basem 
Published: July 2019

ABSTRACT
Hyperammonemic encephalopathy is an under-recognized and potentially fatal complication of Roux-en-Y gastric bypass surgery. We present a case of a 42-year-old woman with no known history of liver disease who experienced worsening encephalopathy 1 year after bariatric surgery. She presented with elevated ammonia and severe encephalopathy requiring intubation. A complete workup led to the diagnosis of a urea cycle disorder. The patient was managed with lactulose, ammonia scavenging agents, and nutritional supplementation with a favorable outcome. We report this case to increase awareness of this condition and urge providers to maintain a high clinical suspicion in the appropriate setting.
Upper Gastrointestinal Bleeding due to Metastatic Endometrial Adenocarcinoma
Authors: Singh Tanveer , Gandhi Darshan , Arora Tanureet , Shapiro Joel 
Published: July 2019

ABSTRACT
Upper gastrointestinal bleeding (UGIB) is a life-threatening complication and a commonly encountered diagnosis requiring hospitalization. It is defined as bleeding proximal to the ligament of Treitz with the most common cause being peptic ulcer disease. There are multiple causes of UGIB and each of them presents its own unique diagnostic and management challenges. We present a rare case of UGIB due to endometrial adenocarcinoma metastatic to the third part of the duodenum. Most common sites of metastasis from endometrial adenocarcinoma are pelvic and paraaortic lymph nodes, and it is very rare for endometrial cancer to metastasize in gastrointestinal tract and then present as UGIB.
A Low FODMAP Diet May Reduce Symptoms in Patients With Fecal Incontinence
Authors: Menees Stacy B. , Chandhrasekhar Deepa , Liew Ee Lane , Chey William D. 
Published: July 2019

INTRODUCTION:Fecal incontinence (FI) is a common complaint and is often associated with diarrhea and urgency. Foods high in fermentable oligo-, di-, and mono-saccharides and polyols (FODMAP) cause symptoms of diarrhea and urgency. Therefore, this study assesses the impact of a low FODMAP diet on the occurrence of FI due to loose stool.METHODS:This study is a retrospective chart review of patients with FI seen in the Michigan Bowel Control Program clinic between August 2012 and December 2017. Patients who had FI with loose stool without red flag signs and who were recommended a low FODMAP diet and underwent formal dietary instruction with a Michigan Medicine dietician were included.RESULTS:Sixty-five patients with FI who underwent formal dietary teaching were included in this study. Eighty-eight percent of the patients were white, and 87% were women with a mean age of 62 years (±14 years). Additionally, the chart review showed that 35% of the patients had FI daily, 21.5% had FI weekly, and 5% had FI monthly. About 64.6% of the patients (42) had reported a reduction in their FI symptoms with the low FODMAP diet. There was no demographic or clinical characteristic that predicted the response to a low FODMAP diet.DISCUSSION:In this case series, dietary manipulation with a low FODMAP diet was a useful tool to treat patients who suffer from FI due to loose stool. Further confirmatory, prospective randomized controlled trials are required to see the true efficacy of a low FODMAP diet in patients who suffer with FI.
Penanaman Nilai–Nilai Karakter Melalui Ekstrakurikuler Hadroh di Mi Ma’arif Giriloyo 1 Imogiri Bantul
Authors: Santosa Sedya 
Published: July 2019

Pada pesenian Hadroh banyak terkandung beberapa nilai yang terkait dengan aspekaspek pendidikan seperti ketuhanan (tauhid), ibadah, dan budi pekerti (karakter). Nilai-nilai karakter di sekolah dapat ditanamkan dengan cara diintegrasikan pada mata pelajaran, dan melalui kegiatan ekstrakurikuler. Di MI Ma’arif Giriloyo 1 Imogiri Bantul, ekstrakurikuler hadroh merupakan salah satu kegiatan ekstrakurikuler yang dijadikan sebagai salah satu wadah dalam upaya madrasah menanamkan nilai-nilai karakter kepada peserta didik.Berdasarkan latar belakang di atas rumusan masalah dalam penelitian ini adalah (1) bagaimana proses kegiatan ekstrakurikuler hadroh di MI Ma’arif Giriloyo 1 Imogiri Bantul, (2) nilai-nilai karakter apa saja yang dapat dibentuk melalui kegiatan ekstrakurikuler hadroh.Penelitian ini merupakan penelitian kualitatif, jenis penelitian lapangan (field reserch) dengan mengambil tempat penelitian di MI Ma’arif Giriloyo 1 Imogiri Bantul. Subjek penelitian ini adalah Guru ekstrakurikuler hadroh dan siswa-siswa yang mengikuti kegiatan ekstrakurikuler hadroh. Untuk informan pendukungnya adalah Kepala Madrasah dan Guru Wali Kelas. Metode pengumpulan data yang digunakan adalah observasi, wawancara, dan dokumentasi. Teknik analisis data yang digunakan meliputi reduksi data, penyajian data, dan penarikan kesimpulan (verifikasi).Hasil penelitian ini menunjukan bahwa ekstrakurikuler hadroh di MI Ma’arif Giriloyo 1 Imogiri Bantul diikuti oleh 12 siswa putra kelas IV dan V dimana runtutan acara pada setiap latihan adalah pembukaan, pemberian materi vokal dan dan materi tabuhan, pembacaan sholawat (penggarapan lagu), dan penutup. Nilai-nilai karakter yang dikembangkan dalam ekstrakurikuler hadroh adalah religius, disiplin, kerja keras, mandiri, rasa ingin tahu, cinta tanah air (nasionalisme), menghargai prestasi, dan tanggung jawab.
Pengaruh Penggunaan Media Big Book Writing terhadap Keterampilan Menulis Bahasa Indonesia Siswa Kelas 5 SD Negeri 1 Pilangbango Madiun
Authors: Dayu Dian Permatasari Kusuma 
Published: July 2019

Keterampilan Menulis adalah salah satu kemampuan berbahasa yang harus dikuasai oleh siswa. Menumbuhkembangkan untuk berani mengekspresikan gagasan atau gagasan siswa dalam bentuk tertulis dapat dikembangkan melalui pendidikan. Namun, sayangnya habituasi ini tidak ditanggapi secara serius dalam sistem pendidikan, sehingga budaya penulisan pada siswa tetap rendah dan masih banyak siswa yang merasa kesulitan untuk melakukan penulisan cerita. Tujuan menulis keterampilan di sekolah adalah agar siswa dapat berbicara bahasa Indonesia untuk mengembangkan ide atau gagasan secara tertulis melalui esai yang mereka buat. Salah satu media yang dapat meningkatkan media pembelajaran menulis adalah Big Book Writing. Media Big Book Writing adalah salah satu media yang dapat merangsang siswa untuk menulis. Big Book Writing adalah buku bacaan dengan ukuran, teks, dan grafis yang hebat.
Rancangan Pembelajaran Tematik Terpadu Matematika dan Mata Pelajaran lain Di SD/MI Kelas 1 Berdasar Konsep Islam Sebagai Agama Hijau
Authors: Mauluah Luluk 
Published: July 2019

Agama Islam disebut agama hijau karena sangat mempunyai perhatian tinggi terhadap kelestarian lingkungan. Dalam Alqur’an banyak ayat tentang pemeliharaan lingkungan yang disebut ayat hijau. Penamaan surah dalam Alqur’an: Al-Baqarah, An-Naml, An-Nahl, Al-Ankabut menggunakan nama-nama binatang. Kemudian hadits-hadits pun banyak yang merekomendasikan umat manusia untuk menjaga alam, menjaga lingkungan baik tanaman, maupun hewan. Hadits tersebut dapat disebut dengan hadits hijau. Konsep Islam sebagai agama hijau dapat digunakan dalam integrasi pembelajaran tematik terpadu. Pada tulisan ini integrasi dirancang untuk kelas 1 tema 7: Benda, Hewan dan Tanaman di Sekitarku. Pada Subtema 2: bacaan “Binatang Peliharaan Beni” dan bacaan “Tempat tinggal Hewan” sangat selaras dengan konsep Islam sebagai agama hijau. Demikian pula untuk subtema 3 dengan bacaan “Merawat Tanaman” sangat cocok dengan konsep Islam sebagai agama hijau. Pembelajaran matematika dengan pembelajaran tematik berdasar konsep Islam agama hijau dapat menggunakan peraga buah-buahan, biji-bijian dan melaksanakan pengukuran panjang pendek menggunakan pohon maupun bagianbagiannya.
Implementasi Manajemen Berbasis Sekolah (Mbs) dalam Mewujudkan Sekolah Mandiri Di SD Muhammadiyah Karangkajen Yogyakarta
Authors: Nurhidayah Nurhidayah 
Published: July 2019

Penelitian ini bertujuan untuk 1) Mengetahui kepemimpinan kepala sekolah di SD Muh Karangkajen, 2) Mengetahui iklim sekolah di SD Muh Karangkajen, 3) Mengetahui otonomi sekolah di SD Muh Karangkajen.Jenis penelitian ini adalah deskripsi secara kualitatif. Data primer diperoleh melalui wawancara, studi pustaka, dokumentasi dan observasi tentang implementasi MBS di SD Muh Karangkajen. Narasumber ditetapkan dengan metode purposive sampling. Objek penelitian adalah SD Muh Karangkajen dan subjek penelitian adalah seluruh warga sekolah dan masyarakat. Teknik analisis data memakai metode induktif dan komparatif.Hasil penelitian menunjukkan bahwa: a) Manajemen berbasis sekolah di SD Muhammadiyah Karangkajen memiliki karakteristik yang khusus di antaranya yaitu kepemimpinan sekolah yang dalam bertindak/ menjalankan tugas kepala Sekolah di SD Muh Karangkajen bertindak sangat arif, bijaksana, adil dan visioner; dalam pengoptimalan pelaksanaan kultur sekolah di antaranya adalah penanaman budaya disiplin; pelaksanaan kegiatan keagamaan secara rutin, pelaksanaan pembelajaran Aktif, Kreatif, Efektif dan Menyenangkan (PAKEM); Upaya sekolah dalam melaksanakan otonomi sekolah di antaranya adalah manajemen tenaga pendidik, manajemen siswa, manajemen kurikulum. b) Manajemen Berbasis Sekolah yang ada di SD Muh Karangkajen dapat membangun standar kompetensi guru, pengembangan kurikulum melalui pembelajaran yang aktif, kreatif, dan menyenangkan. c) Pelaksanaan manajemen berbasis sekolah di SD Muhammadiyah Karangkajen merupakan langkah pengelola sekolah dalam membangun kemandirian dalam beberapa bidang, yaitu bidang pengadaan tenaga kependidikan, pengembangan kurikulum sekolah.
Penerapan Model Kooperatif Tipe Simultaneous Roundtable untuk Meningkatkan Keterampilan Sosial Siswa
Authors: Sriwulan Agus 
Published: July 2019

Penelitian ini bertujuan mendeskripsikan penerapan model kooperatif tipe Simultaneous RoundTable untuk meningkatkan keterampilan sosial siswa di SDN Tunjungsekar 5 Malang. Jenis penelitian ini merupakan Penelitian Tindakan Kelas yang terdiri dari 2 siklus. Masing-masing siklus terdiri dari empat tahap, yaitu tahap perencanaan, pelaksanaan, pengamatan, dan refleksi. Subjek penelitian ini adalah siswa kelas II B SDN Tunjungsekar 5 Malang tahun pelajaran 2015/2016 yang berjumlah 25 orang. Data tentang keterampilan sosial siswa dikumpulkan melalui lembar observasi dan wawancara. Data yang telah terkumpul kemudian dianalisis dengan menggunakan teknik analisis deskriptif kualitatif. Pada siklus I, persentase keterampilan sosial siswa diperoleh hasil sebesar 55% dan mengalami peningkatan yang signifikan pada siklus II sebesar 87%. Berdasarkan hasil penelitian ini, menunjukkan adanya peningkatan keterampilan sosial siswa melalui penerapan model kooperatif tipe Simultaneous RoundTable yang mencakup sub aspek (1) kemampuan berkomunikasi dengan siswa lain, (2) menjalin hubungan pertemanan dengan teman sebaya, (3) mendengarkan pendapat teman, (4) memberi dan menerima kritik dari orang lain, dan (5) memberi atau menerima umpan balik. Kata Kunci: Model kooperatif tipe Simultaneous RoundTable, Keterampilan sosial siswa
Manajemen Kurikulum Pendidikan Agama Islam dan Budi Pekerti Jenjang SMA Bermuatan Keilmuan Integrasi Interkoneksi
Authors: Hidayati Wiji 
Published: July 2019

Islamic education and character education within the 2013 Curriculum at Senior High School in Indonesia are included in group A topics which is considered as compulsory. The central government has formulated purposes, learning outcome competence, core competence as well as basic competence of those two topics. Thus, it requires high-quality management to achieve the standards. However, in reality, Islamic education and character education teachers, particularly at State Senior High School I Pakem, Yoyakarta, are rarely aware of this scientific content in relation to management activities. It is admitted there that management activity is, in fact, teacher obligation yet it is often regarded merely as routine. This research, which is aimed at describing curriculum management on Islamic education and character education with integration –interconnection scientific content at Senior High School, is a field study using qualitative approach. The subjects are Islamic education and character education teachers at State Senior High School I Pakem Yogyakarta while the object is the curriculum management of Islamic education and character education of Senior High School class X, XI and XII. Data were gathered using observation, interview and documentation which are then analyzed based on Matthew B. Miles and A. Michael Huberman. Flow model was used as data analysis including three elements namely, data gathering which was done along with data reduction using classification, topic concentration and generalization, abstraction and rough data transformation; data analysis which comprises data display, information arrangement and conclusion or data verification under the topic of curriculum management of Islamic education and character education at Senior High School particularly on planning, organizing, actuating, and controlling phase related to integration-interconnection among bayani, irfani and burhani. The result shows that, at class X, there is core topic under the themes of ”Living virtuous life” and ”Managing wakaf truthfully”, while at class XI, the core topic is ”Hi Moslem warriors, wake up and rise!”, whereas at class XII, the core topic is ”Worshiping spiritfully by believing on the doomsday”.
Kepemimpinan Berbasis Core Values Sekolah Unggulan di Malang
Authors: Hambali Muh. 
Published: July 2019

AbstractVortex of globalization necessitates a school establishes certain advantages and challenges of the proliferation of educational institutions, if private schools are not improving the human resource and does not indicate a particular advantage innovations from other schools will be degraded public trust. A school principal requires a model of leadership in creating a level of trust and quality of academic services that exceed the expectations of internal and external school school. School leadership puts the organization a competitive advantage as a core value as the value inherent in a school community. The competitive advantage of the organization is how the organization creates value service performance advantages of low cost and product differentiation. Two such approaches are needed schools that want to deliver maximum quality academic services and demonstrate excellence by means of efficiency. The goal is to assess school leadership based on core values, characteristics of quality implementation in schools and the implementation of the concept of quality assurance systems. Three objectives are based on research and discussion of literature that leadership with the guarantee is related to the value system that was built through the vision that inspired each school community. The vision of leadership based on values ​​that are mutually agreed upon has spawned a school of excellence amidst the proliferation of educational institutions. Educational institutions are not seen as a social investment, but the institution has become a noble industry. Based on the explanation, the leadership of principals need to have different perspectives on quality assurance paradigm is very different between the service field service with the service areas of goods. Notch education that are in the area of ​​services.Keywords: core values-based leadership, excellent schools
Peran Sekolah dalam Membentuk Keterampilan Wirausaha Berbasis Tauhid di SD Entrepreneur Muslim Alif-A Piyungan Bantul Yogyakarta
Authors: Wahyuni Widia Riska , Hidayati Wiji 
Published: July 2019

This study aims to determine the roles and ways undertaken by schools in inculcating the character of entrepreneurial-based tauhid in order to be able to help learners gain knowledge about entrepreneurship from early childhood as well as help to build quality of Islamic School with high trust and quality. This research is a qualitative research conducted at Entrepreneur Elementary School Muslim ALIF-A Piyungan Bantul Yogyakarta. The data is collected using observation, interviews and documentation. The results of this study are: firstly, the role of schools in the formation of students’ entrepreneurial skills is demonstrated by activities in schools to acquire knowledge and skills by assisting learners in shaping character and personality, and be able to interact with their environments through integrated thematic learning. Learners have to be active, and are encouraged to recognize and accept the values of entrepreneurship in developing the ability of learners to perform daily activities. Secondly, in the formation of entrepreneurial character, the school has six basic principles, they are: educative, effective, strategic, empirical, leadership, and productive through three learning zones, namely spiritual zone, learning zone, and entrepreneur zone based on the character of each program. Thirdly, the results of the system can be seen from the students’ attitude of independent, tawakkal, creative, innovative, confident, discipline, have a sense of responsibility and tolerate others.