bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tumour necrosis factor, interferon-gamma and interleukins as predictive markers of antiprogrammed cell-death protein-1 treatment in advanced non-small cell lung cancer: a pragmatic approach in clinical practice
Authors: Boutsikou Efimia , Domvri Kalliopi , Hardavella Georgia , Tsiouda Dora , Zarogoulidis Konstantinos , Kontakiotis Theodoros 
Published: April 2018

Background: The emergence of novel antiprogrammed cell death protein-1 (PD-1) inhibitors in non-small cell lung cancers (NSCLC) has revolutionized the therapeutic landscape of this disease. Although overall survival (OS) has improved in the first- and second-line therapy settings for advanced NSCLC, the benefit is not universal. In a climate of global scrutiny for healthcare costs and potential for toxicities related to immunotherapy, appropriate patient selection is crucial. The aim of this study was to evaluate potential prognostic and predictive biomarkers interferon-gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α) and a panel of interleukins (ILs) in the peripheral blood, and assess any correlation with response to anti-PD-1 inhibition, progression-free survival and OS in NSCLC patients. Methods: We prospectively studied 26 NSCLC patients that received immunotherapy (either pembrolizumab or nivolumab). IFN-γ, TNF-α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10 and IL-12 were analyzed by flow cytometry at the time of diagnosis and at 3 months after initiation of anti-PD-1 inhibition. Results: Increased cytokine values (IFN-γ, TNF-α, IL-1β, IL-2, IL-4, IL-6 and IL-8) at the time of diagnosis and at 3 months after initiation of treatment were significantly correlated with improved response to immunotherapy and prolonged OS. There was no correlation between cytokine levels and programmed cell death ligand-1 (PD-L1) expression. Conclusions: Increased IFN-γ, TNF-α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10 and IL-12 levels resulted in better response to NSCLC anti-PD-1 inhibition and longer survival, and this could potentially play an important role in selecting patients that would benefit from anti-PD-1 inhibitors.
Tropical Riffs
Authors: Borge Jason 
Published: April 2018

In Tropical Riffs Jason Borge traces how jazz helped forge modern identities and national imaginaries in Latin America during the mid-twentieth century. Across Latin America jazz functioned as a conduit through which debates about race, sexuality, nation, technology, and modernity raged in newspapers, magazines, literature, and film. For Latin American audiences, critics, and intellectuals—who often understood jazz to stem from social conditions similar to their own—the profound penetration into the fabric of everyday life of musicians like Duke Ellington, Dizzy Gillespie, and Charlie Parker represented the promises of modernity while simultaneously posing a threat to local and national identities. Brazilian antijazz rhetoric branded jazz as a problematic challenge to samba and emblematic of Americanization. In Argentina jazz catalyzed discussions about musical authenticity, race, and national culture, especially in relation to tango. And in Cuba, the widespread popularity of Chano Pozo and Dámaso Pérez Prado popularity challenged the United States' monopoly on jazz. Outlining these hemispheric flows of ideas, bodies, and music, Borge elucidates how "America's art form" was, and remains, a transnational project and a collective idea.
Mortality and cause of death postoperatively in patients with a hip fracture
Authors: Choi H. G. , Lee Y. B. , Rhyu S. H. , Kwon B. C. , Lee J. K. 
Published: April 2018

Aims The aim of this study was to compare the rate of mortality and causes of death in Korean patients who undergo surgery for a fracture of the hip, up to 11 years after the injury, with a control group from the general population. Materials and Methods National cohort data from Korean Health Insurance Review and Assessment Service – National Sample Cohort were used. A ratio of 1:4 matched patients with a fracture who underwent surgery (3383, fracture group) between 2003 and 2012, and controls (13 532) were included. The matches were processed for age, gender, income, and region of residence. We also undertook analyses of subgroups according to age and gender. The mean follow-up was 4.45 years (1 to 11). Results The prevalence of hypertension, diabetes, and stroke was significantly higher in the fracture group and dyslipidemia in the controls. Both crude and adjusted hazard ratios (HR) for the rate of mortality in the fracture group were > 2 (crude HR 2.03, 95% confidence interval (CI) 1.91 to 2.17, p < 0.001; adjusted HR 2.07, 95% CI 1.94 to 2.21, p < 0.001). The HRs were also > 2 for both men and women, and for both those aged ≥ 50 years and < 50 years. However, for those aged < 50 years, they were insignificant. The rates of mortality due to all 11 major causes of death classified following Korean standard classification of diseases were significantly higher in the fracture group compared with the control group, except those in the mental and behavioral disorders category. Conclusion The rate of mortality in the fracture group was significantly higher than in the control group up to 11 years after the surgery. The rate of death due to almost every major cause was significantly higher in the fracture group compared with the control group. Cite this article: Bone Joint J 2018;100-B:436–42.
Padrões de consumo de álcool em estudantes da Universidade de Aveiro: relação com comportamentos de risco e stress
Authors: Rodrigues Pedro F. S. , Salvador Ana C. F. , Lourenço Inês C. , Santos Luísa R. 
Published: April 2018

Resumo: O consumo excessivo de álcool em estudantes universitários tem sido focode grandes preocupações, não só devido aos seus efeitos negativos na saúde, mastambém porque habitualmente leva a comportamentos de risco, como a condução sobo efeito de álcool, ou relações sexuais sem proteção. Outro aspeto muitoverificado entre os estudantes universitários, e que parece ser um dos motivos queleva ao consumo de álcool são os níveis de stress. Neste estudo, realizado a760 estudantes da Universidade de Aveiro, verificámos que os participantes apresentamelevados consumos de álcool, sobretudo em festas académicas. Os comportamentosde risco associados não se mostram significativos. Verificámos igualmente que omaior consumo de álcool está associado ao sexo masculino. Também se constatou queos estudantes universitários que saem de casa dos pais/da sua residência apresentammaiores consumos de álcool. Relativamente à perceção de stress, verificámos queos estudantes universitários de Aveiro apresentam níveis moderados de stress eque estes se encontram negativamente correlacionados com os consumos de álcool.Os nossos resultados são discutidos à luz das teorias existentes sobre ospadrões de consumo de álcool em estudantes universitários.Palavras-chave: estudantes universitários, consumo de álcool,comportamentos de risco, stress Abstract: The alcohol consumption in college students had beena point of enormous concerns, not only because the alcohol has negative effectsfor the health, but also because frequently it has risk behaviours associated,for instance driving sob alcohol effect or sexual relations sob alcohol effect.Other aspect that we can view in college students is stress that probably it’sa motive for the alcohol consumption. In this study, that it was realized with 760students at University of Aveiro, we found that students consume alcohol a lot,particularly in academics celebrations. However, the risk behaviours aren’tsignificants in our sample. We also found that higher consumption of alcohol isassociated with masculine students and with students that are dislocated of thefamilies’ house. Our sample has a medium level of stress. The stress’ studentsis negatively correlated with the alcohol consumption. Our results arediscussed in light of existing theories about the alcohol consumption incollege students. Keywords: college students, alcohol consumption, riskbehaviours, stress
A survey of the vulnerable Cuvier’s gazelle (Gazella cuvieri) in the mountains of Ait Tamlil and Anghomar, Central High Atlas of Morocco
Authors: El Alami Abderrazak 
Published: April 2018

Abstract
This article reports data on the distribution of the Cuvier’s gazelle in the mountains of Ait Tamlil and Anghomar, Central High Atlas. In this study, a combination of standardized interviews combined with a field survey to gather information about gazelles in the region was used. Results confirm the presence of the Cuvier’s gazelle in the high summits of the region limited by the villages of Tikhfist, Megdaz and the lake of Tamda n’Anghomar. The species is threatened by overhunting and habitat destruction. The conservation of Gazella cuvieri is required to increase habitat protection, to enforce the law against capturing gazelles and to raise the awareness of local people about the conservation of this mammal.
Crystal structure of 1,1′-((1E,1′E)-(((ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanylylidene))bis(methanylylidene))bis(naphthalen-2-olato)cobalt(II), C36H26N2O4Co
Authors: Li Guo Qiang , Zhao Yan Ling , Jiang Yong Sen , Yu Yun Chun , Fang Jun Ran , Xu Qiang 
Published: April 2018

Abstract
C36H26N2O4Co, monolinic, C2/c (no. 15), a = 43.230(14) Å, b = 17.100(6) Å, c = 11.275(4) Å, β = 103.112(4)°, V = 8118(5) Å3, Z = 12, R
gt(F) = 0.0370, wR
ref(F
2) = 0.0931, T = 100(2) K.
Crystal structure of dimethanol-(μ2-squarato-κ2
O:O′)-tetrakis(tri-p-tolylphosphane-κP)disilver(I) – methanol (1/2), C92H98Ag2O8P4
Authors: Liu Kuanguan , Nie Jing 
Published: April 2018

Abstract
C92H98Ag2O8P4, triclinic, P1̄ (no. 2), a = 11.179(3) Å, b = 12.623(3) Å, c = 15.656(4) Å, α = 83.607(8)°, β = 78.636(9)°, γ = 83.128(9)°, V = 2141.6(10) Å3, Z = 2, R
gt(F) = 0.0398, wR
ref(F
2) = 0.1034, T = 294(2) K.
Crystal structure of aqua(1-(2-pyridyl)ethanone oxime-κ2
N,N′)(1-(2-pyridyl)ethanone oximato-κ2
N,N′) nitrate monohydrate, C14H19N5O7Cu
Authors: Zuo Jian 
Published: April 2018

Abstract
C14H19N5O7Cu, triclinic, P1̅ (no. 2), a = 10.8164(15) Å, b = 11.4831(17) Å, c = 15.423(2) Å, α = 101.035(3)°, β = 100.538(2)°, γ = 101.708(2)°, V = 1791.5(4) Å3, Z = 4, R
gt(F) = 0.0416, wR
ref(F
2) = 0.1131, T = 298(2) K.
Crystal structure of 3,5-bis(trifluoromethyl)benzyl(Z)-N-(adamantan-1-yl)morpholine-4-carbothioimidate, C24H28F6N2OS
Authors: Al-Wahaibi Lamya H. , Hassan Hanan M. , Ghabbour Hazem A. , El-Emam Ali A. 
Published: April 2018

Abstract
C24H28F6N2OS, monoclinic, P21/n (no. 14), a = 17.4112(7) Å, b = 8.3694(3) Å, c = 17.6728(7) Å, β = 104.612(2)°, V = 2492.01(17) Å3, Z = 4, R
gt(F) = 0.0603, wR(F
2) = 0.1704, T = 293(2) K.
Synthesis and crystal structure of 6-carboxy-1-(3,5-dicarboxyphenyl)-1H-benzo[d]imidazol-3-ium-5-carboxylate dihydrate, C18H12N2O8
Authors: Yun Meng , Dong Xiu-Yan 
Published: April 2018

Abstract
C18H12N2O8, triclinic, P1̄ (no. 2), a = 8.4592(10) Å, b = 9.8442(11) Å, c = 11.2565(12) Å, α = 66.892(3)°, β = 86.069(3)°, γ = 81.658(4)°, V = 852.97(17) Å3, Z = 2, R
gt(F) = 0.0609, wR
ref(F
2) = 0.1557, T = 153(2) K.
Crystal structure and molecular packing of O-ethyl (2-chlorophenyl)carbamothioate, C9H10ClNOS
Authors: Yeo Chien Ing , Tiekink Edward R.T. 
Published: April 2018

Abstract
C9H10ClNOS, triclinic, P1̄ (no. 2), a = 7.2277(3) Å, b = 9.9791(3) Å, c = 14.7725(7) Å, α = 81.007(3)°, β = 82.268(4)°, γ = 73.210(3)°, V = 1003.01(7) Å3, Z = 4, R
gt(F) = 0.0364, wR
ref(F
2) = 0.0828, T = 100(2) K.
Religious Diversity, Social Cohesion, and the Role of Interfaith Cooperation in Resilient Global Cities
Authors: Banout Tony , Henderson Brad 
Published: April 2018

Abstract
The city of the future will have to come to terms with astronomical population growth comprised of individuals and communities that differ on matters of fundamental beliefs living in increasingly close proximity. The test will be whether religious diversity increasingly leads to clashing parochialisms or unlocks possibilities for human flourishing. With 7.5 billion people urbanized by 2050, cities simply must include attention to religious diversity, and the science of social capital and interfaith cooperation can inform the discourse of resiliency as humanity prepares. Ample sociological research supports the conclusion that societies thrive where and when they are able to build trusting relationships across lines of deep difference. The inverse failure to do so is a direct danger to civil peace. This article charts a path forward to building and sustaining those relationships in an urban setting.
Fe3+-bis-ethylenediamine complex bridged periodic mesoporous organosilica for the efficient removal of arsenate and chromate
Authors: Parambadath Surendran , Mathew Aneesh , Kim Su Yeon , Park Sung Soo , Ha Chang-Sik 
Published: April 2018

Abstract
The direct removal of arsenate (AsO4
3−) and chromate (CrO4
2−) from water were achieved using a Fe3+-bis-ethylenediamine complex-bridged periodic mesoporous organosilica with a 20% organosilane content (Fe-EDPMO-20). The bridged Fe3+-bis-ethylenediamine complex was introduced to the pore wall of the PMO by combining the pre-complexation and co-condensation processes. N,N′-bis[3-(triethoxysilyl)propyl]ethylenediamine (TESEN) and tetramethyl orthosilicate (TMOS) as silica precursors were used with cetyltrimethylammonium bromide (CTABr) as a surfactant under basic conditions for the preparation of highly ordered Fe-EDPMO-20. Transmission electron microscopy, X-ray diffraction, and N2 adsorption-desorption measurements confirmed that the Fe-EDPMO-20 had an ordered hexagonal p6mm mesostructure. The material had a Brunauer-Emmett-Teller surface area of 734 m2 g−1, pore diameter of 2.6 nm, and pore volume of 0.61 cm3 g−1. UV-vis and X-ray photoelectron spectroscopy confirmed that Fe3+ was embedded in the coordination site by the nitrogen atoms from ethylenediamine. The adsorption efficiencies of arsenate and chromate ions by Fe-EDPMO-20 were examined as a function of pH, stirring time, amount of adsorbent, and initial concentration of metal ion solution. The maximum adsorption for arsenate and chromate were 156 and 102 mg g−1 within 6 and 24 h, respectively, at pH 4.
Design of smart tools to support pre- and intra-operative use of surgical navigation systems
Authors: Gieseler Oliver , Alvarez-Gomez Julio C. , Roth Hubert , Wahrburg Jürgen 
Published: April 2018

Abstract
In this paper we present novel solutions to support the application of computer assisted surgical interventions in which optical surgical navigation systems based on stereo cameras are used. The objective is to improve both the pre-operative setup and the intra-operative use of the navigation system. Following a short introduction describing the potential for improvements of existing navigation systems new approaches and the components to implement them are described. The pre-operative alignment of the stereo camera is made easier by attaching a small graphic display to its tripod which can show how much of the operating area is covered by the measurement volume of the camera. The intra-operative application is improved by a mechanism for motorized camera motions in order to follow the position of surgical instruments. Furthermore a small display can be attached to a surgical instrument which clearly indicates to the surgeon how to guide the instrument in order to stay on the planned trajectory.
Individualisierung von Religion?
Authors: Lienau Detlef 
Published: April 2018

ZusammenfassungAm Beispiel des Pilgerns wird die Annahme einer Individualisierung von Religion erörtert. Ergebnisse einer qualitativ-empirischen Studie zur religiösen Erfahrung von Pilgern werden in die für Individualisierung relevanten theoretischen Konzepte Subjektivität, Sozialität und Autonomie eingebracht. Religion wird als selbst gemachte Erfahrung, also subjektiviert, sichtbar. Autonomie wird zwar gegenüber sozialen Ansprüchen behauptet, zugleich aber aufgehoben im Sich-Ausliefern an und Aufgehen in den Dingen und Eindrücken. Die soziologischen Konzepte zu Privatisierung und Entscheidungscharakter von Religion bestätigen sich im Pilgern nicht. Die Frage nach der Individualisierung von Religion ist für das Pilgern mithin differenziert zu beantworten: Religion ereignet sich im je einzelnen Subjekt, das sich hinsichtlich der sozialen Einbindung pragmatisch verhält, während es eine gewissheitsstiftende ent-individualisierende Einbindung in scheinbar vorsoziale Dinge wie Natur und den eigenen Leib sucht.
The Medium is the Messenger?
Authors: Roth Mirko 
Published: April 2018

Zusammenfassung
In diesem Aufsatz wird eine kommunikations- und medientheoretische Untersuchung ausgewählter Divinationspraktiken unternommen. Im Zentrum stehen hierbei das Giftorakel der zentralafrikanischen Zande sowie die arabisch-islamische Geomantie. Dieses Unternehmen hat den Zweck, drei Thesen bezüglich Medien religiöser Kommunikation zu erproben, die sich dem Autor aus der Auseinandersetzung mit Ritualen und speziell Divinationsformen aus unterschiedlichen soziokulturellen Kontexten ergeben haben:1) Divinationsmedien unterscheiden sich in frappierender Weise von Medien der Alltagskommunikation; 2) diese besonderen Medien ermöglichen eine Kommunikation zwischen Wirklichkeitsbereichen (i. S. der Strukturen der Lebenswelt [Schütz/Luckmann]) und verkörpern damit ein fundamentales „Dazwischen“; 3) von einer Innenperspektive betrachtet, werden Divinationsmedien oft als aktive Kommunikationspartner konzipiert und wahrgenommen – selbst wenn diese aus einer Beobachterperspektive unbelebte Paraphernalia sind.Um eine Grundlage für die Plausibilisierung dieser Thesen zu schaffen, ist anfänglich von Kommunikation und Medien sowie den Besonderheiten religiöser Kommunikation und Medien religiöser Kommunikation die Rede. Auf die detaillierte Beschreibung der Divinationspraktiken folgen ihre kommunikationstheoretische Analyse sowie eine zeichen- und medientheoretische Deutung dieser Ergebnisse.Das Ziel dieses Aufsatzes liegt neben der Plausibilisierung seiner Thesen auch darin, Impulse für die religionswissenschaftliche Debatte um Medien, Materialität und Performanz zu liefern. Gerade in den Ergebnissen der Divinationsforschung sieht David Morgan, wie er jüngst in Material religion schrieb, ein ertragreiches Feld.
Theory and Empiricism of Religious Evolution (THERE): Foundation of a Research Program. Part 1
Authors: Krech Volkhard 
Published: April 2018

AbstractThis two-part article presents the research program for a theory and empirical analysis of religious evolution. It is assumed that religion isprimarilya co-evolution to societal evolution, which in turn is a co-evolution to mental, organic, and physical evolution. The theory of evolution is triangulated with the systems theory and the semiotically informed theory of communication, so that knowledge can be gained that would not be acquired by only one of the three theories: The differentiation between religion and its environment can be reconstructed based on the theory of evolution. The elements of the theory of evolution can be understood as the formation of systems. The semiotically informed theory of communication clarifies the conditions of the combination of both the systems theory and the theory of evolution as well as its objects. In turn, the combination of the systems theory and the theory of evolution can describe how communication – including religion and science – evolves and is structured.
The Mahā Kumbh Melā in Allahabad 2013
Authors: Gäbel Cora 
Published: April 2018

AbstractThe following article deals with the Mahā Kumbh Melā1in Allahabad (Uttar Pradesh, northern India) and the practices of Hindu world renouncers2during this festival. In 2013, the year under study, approximately 120 million renouncers and lay pilgrims attended the festival. After a brief overview of the academic discussion on Hindu renunciation, the article proceeds to outline the mythology, history, and meaning of the Kumbh Melā. Subsequently, it presents the festival from the renouncers’ point of view. This section of the article summarizes the functions of the festival, describes two particular forms of meals (bhaṇḍārāsandannakṣetras), and outlines the daily routine of the participants. Finally, the article discusses the inner-worldly asceticism of lay pilgrims, the main participants, as well as the ritual bathing during the festival, a crucial part of the Kumbh Melā for all participants.
Kompetenzen islamischer Religionslehrkräfte – eine empirische Studie
Authors: Kamcili-Yildiz Naciye 
Published: April 2018

Zusammenfassung:
Das Forschungsprojekt „fachwissenschaftliche und fachdidaktische Kompetenzen von muslimischen Religionslehrkräften“ ist eine empirische Arbeit, in der die fachwissenschaftlichen und fachdidaktischen Kompetenzen muslimischer Lehrkräfte überprüft werden. Auf der Grundlage des entwickelten Kompetenzmodells wurde unter Beteiligung der islamischen Theologie und Religionspädagogik ein Fragebogen mit Items entwickelt, womit die Kompetenzen der derzeit eingesetzten Religionslehrkräfte in der Sekundarstufe I erfasst werden. Die Bewertung der Ergebnisse soll insbesondere dazu dienen, systematische Empfehlungen für die Aus- und Weiterbildung zu geben.
Förderung interreligiöser Dialog- und Kooperationskompetenz in der Hochschuldidaktik. Empirische Analyse eines kooperativen Seminarkonzepts
Authors: Kürzinger Kathrin S. , Schneider Sibylle 
Published: April 2018

Zusammenfassung:
Aufgrund der steigenden Bedeutung interreligiösen Lernens, das zunehmend auch strukturell bei der Konzeption von Religionsunterricht eine Rolle spielt, müssen angehende Lehrkräfte adäquat ausgebildet werden. Um ihnen den Erwerb interreligiöser Dialog- und Kooperationskompetenz sowie eigene Kooperationserfahrungen beim Lernen und Lehren bereits während der Ausbildung an der Universität zu ermöglichen, wurde ein hochschuldidaktisches Seminarkonzept entwickelt, das mittels eines Fragebogens evaluiert wird. Die Ergebnisse des Pretests von Seminarkonzeption und Fragebogeninstrument werden im Beitrag vorgestellt.
Das Kamishibai als erzählgenerierender Eingangsstimulus für narrative Interviews mit Kindern
Authors: Ulfat Fahimah 
Published: April 2018

Zusammenfassung:
Narrationen sind für die Erforschung von lebensweltlichen Erfahrungen von Kindern zentral. Dazu bedarf es qualitativer Methoden, die es ermöglichen, Narrationen anzuregen. Solche Erhebungsmethoden erfordern einen Stimulus, der sowohl breit als auch spezifisch formuliert ist. Auf diese Weise wird den Interviewten einerseits Raum für ihre eigenen „Relevanzsysteme“ eröffnet, andererseits der gewünschte Erfahrungsbereich angesteuert. Gerade in Interviews mit Kindern stellt sich die Frage, wie ein Stimulus gestaltet sein muss, der die interviewten Kinder zum Erzählen anregen und eine offene Kommunikation ermöglichen soll. Der Fokus des folgenden Beitrags liegt auf der Vorstellung des Erzähltheaters Kamishibai als einer möglichen Option, Narrationen bei Kindern anzuregen und so Zugang zu den lebensweltlichen Erfahrungen als auch den Orientierungen von Kindern zu erhalten.
Gymnasien in kirchlicher Trägerschaft zwischen christlicher Profilierung und exzellentem Leistungsanspruch – Schulleiter- und Schülerperspektiven
Authors: Niemann Mareke 
Published: April 2018

Zusammenfassung:
Gymnasien in kirchlicher Trägerschaft bewegen sich zwischen einem exzellenten Leistungsanspruch und dem Ideal einer christlichen Vergemeinschaftung. Diese Gymnasien können aufgrund ihrer selektiven Zulassungsverfahren und ihres besonderen Profils als exklusive Schulen definiert werden. Der Beitrag bietet anhand von qualitativen Rekonstruktionen des Datenmaterials zweier konfessioneller Gymnasien Einblicke in das Verhältnis einer christlichen Profilierung und der schulischen Leistungslogik. Insbesondere werden Erkenntnisse über die Deutungen der schulischen Akteure möglich. Es zeigt sich ein Spannungsfeld, für das sich auf der institutionellen Ebene für die beiden Schulen unterschiedliche Umgangsformen abstrahieren lassen. Außerdem unterscheidet sich die Wahrnehmung in der institutionellen und schülerbiographischen Perspektive.