bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting the risk of mortality in children with dengue-induced hepatitis admitted to the paediatric intensive care unit
Authors: Nguyen Thanh Tat , Ngo Phuong Thi-Mai , Vo Luan Thanh 
Published: October 2024

BACKGROUND
Dengue-associated acute liver failure (PALF) accounts for a high mortality rate in children admitted to the pediatric intensive care unit (PICU). To date, there is a lack of data on clinical algorithms for estimating the risk of mortality in pediatric patients with dengue-induced severe hepatitis (DISH).
AIM
To determine the prevalence of PALF and identify the predictors of mortality among patients with DISH.
METHODS
This single-institution retrospective study was performed at a tertiary pediatric hospital in Vietnam between 2013 and 2022. The primary outcome was in-hospital mortality in pediatric patients with DISH, which was defined as either aspartate aminotransferase > 350 IU/L or alanine aminotransferase > 400 IU/L. Prognostic models for estimating the risk of death among patients with DISH were developed using a predefined set of clinical covariables and hepatic biomarkers on PICU admission and during the first 72 hours of admission. Area under the curve, multivariable logistic regression, and multiple imputation using the chained equation for missing values were performed. Backward stepwise model selection based on the Akaike information criterion was employed. Bootstrapping, calibration slope, and Brier score were used to assess the final models.
RESULTS
A total of 459 children with DISH were included in the analysis. The median patient age was 7.7 years (interquartile range: 4.3-10.1 years). The prevalence of dengue-associated PALF in children with DISH was 18.3%. Thirty-nine DISH patients developing PALF (8.5%) died. Hepatic biomarkers, including the international normalized ratio (INR) ≥ 2.11 and total serum bilirubin (≥ 1.7 mg/dL), showed high predictive values for mortality (all P values < 0.001). Multivariable models showed the significant clinical predictors of death from dengue-induced PALF in patients with DISH, including reduced level of consciousness (pain and unresponsive levels on the Alert, Verbal, Pain, Unresponsive scale), high vasoactive-inotropic score (> 30), and elevated levels of blood lactate, INR, and serum bilirubin. The final prognostic model demonstrated high discrimination, Brier score, and an acceptable calibration slope.
CONCLUSION
The prevalence of PALF in children with DISH is 18.3%. We developed robust prognostic models to estimate the risk of death in hospitalized children with severe dengue-induced hepatitis.
Impact of diabetes mellitus on mortality in pulmonary hypertension: A systematic review and meta-analysis
Authors: Padte Smitesh , Mehta Priyal , Bansal Vikas , singh Niti , Sunasra Rayyan , Goyal Vidhi , Chaudhary Raunaq B , Junnarkar Yash , Shah Vidhi , Arshad Zara , Nawaz Faisal A , Surani Salim , Kashyap Rahul 
Published: October 2024

BACKGROUND
Pulmonary hypertension (PH) is a progressive disease characterized by endothelial dysfunction and vascular remodeling and is a leading cause of mortality worldwide. Although it is independently associated with multiple comorbidities, the impact of diabetes mellitus (DM) on mortality in patients with PH remains uncertain. To address this issue, we conducted a systematic review and meta-analysis to investigate the effect of DM on survival in patients with pulmonary hypertension.
AIM
To investigate the impact of diabetes mellitus on mortality in pulmonary hypertension patients.
METHODS
We conducted a comprehensive search of four major electronic bibliographic databases like PubMed, Google Scholar, Scopus, and Embase, and identified 106 relevant studies, out of 1561 articles, published since the year 2000 for full-text review. Fourteen retrospective and prospective cohort studies that compared survival between patients with DM and those without DM in the context of PH were deemed eligible for inclusion in our meta-analysis. The study was registered on PROSPERO with the identifier CRD42023390232.
RESULTS
A total of 116455 patients with PH were included in the meta-analysis, of whom 41228 suffered from DM and 75227 did not. The results of our meta-analysis indicate an elevated mortality rate among PH patients with diabetes mellitus in comparison to those without DM [odds ratio (OR) = 1.40, 95%CI: 1.15–1.70, P = 0.0006]. The meta-regression analysis unveiled a statistically significant negative association between mean age and effect size (coefficient = -0.036, P value = 0.018). Conversely, a statistically significant positive association was detected between female proportion and effect size (coefficient = 0.000, P value < 0.001).
CONCLUSION
Our meta-analysis, which included approximately 116500 PH patients, revealed that the presence of diabetes mellitus was associated with increased odds of mortality when compared to non-diabetic patients. The meta-regression analysis indicates that studies with older participants and lower proportions of females tend to exhibit smaller effect sizes. Clinically, these findings underscore the importance of incorporating diabetes status into the risk stratification of patients with PH with more aggressive monitoring and early intervention to improve prognosis potentially.
Combinatorial proof of Girard-Waring formula
Authors: Łukasz Bożyk  
Published: November 2024

\noindent The well-known and celebrated identity of Girard (1629) and Waring (1762) states that
\[x^n+y^n=\sum_{m=0}^{\lfloor n/2\rfloor}(-1)^m\frac{n}{n-m}\binom{n-m}{m}\left(xy\right)^m\left(x+y\right)^{n-2m}\]
and can be easily proven algebraically (see H.W. Gould, The Girard--Waring power sum formulas for symmetric functions and Fibonacci sequences,} Fibonacci Quart. 37 (1999), no. 2, 135--140). In this note, we provide a combinatorial proof of this identity.
ANALISIS PENDAPATAN USAHATANI JAGUNG (ZEA MAYS L.) (STUDI KASUS DI DESA LAINUNGAN KECAMATAN WATANG PULU KABUPATEN SIDENRENG RAPPANG)
Authors: Ine Henryani 
Published: November 2024

Jagung merupakan komoditas tanaman pangan yang memiliki peranan penting dan strategis dalam pembangunan nasional. Permintaan jagung terus mengalami peningkatan sebagai dampak dari berkembangnya industri peternakan, terutama peternakan ayam petelur. Kabupaten Sidenreng Rappang merupakan salah satu Kabupaten yang berpotensi untuk pengembangan komoditi jagung karena memiliki permintaan pasar lokal yang cukup tinggi terutama pemenuhan pakan ternak ayam ras. Penelitian ini bertujuan untuk menganalisis pendapatan dan kelayakan usahatani jagung. Penelitian dilaksanakan di Desa Lainungan, Kecamatan Watang Pulu, Kabupaten Sidenreng Rappang. Penelitian ini menggunakan pendekatan kuantitatif untuk menganalisa seberapa besar pendapatan dan bagaimana kelayakan usahatani jagung. Populasi dalam penelitian ini adalah semua petani jagung di Desa Lainungan dan sampel 40 petani yang ditentukan dengan teknik sampel acak sederhana menggunakan rumus slovin. Rata-rata pendapatan petani sebesar Rp 43.926.000 (Musim tanam/3,32 Ha), total biaya sebesar Rp. 17.490.000. Rata-rata produksi 6.675 Kg dengan harga Rp 3.685/Kg sehingga diperoleh penerimaan sebesar Rp 61.415.00. Penerimaan Per Ha sebesar Rp. 18.498.000, total biaya Rp. 5.268.000 dan pendapatan sebesar Rp. 13.231.000 (Musim tanam/Ha). Nilai R/C sebesar 3,51 > 1, dengan interpretasi bahwa usahatani jagung layak untuk diusahakan. Nilai B/C sebesar 2,51 > 1, dengan interpretasi jika setiap petani menggunakan modal usaha sebesar 1 rupiah, maka akan menghasilkan keuntungan 2,51 rupiah.
PELATIHAN PEMANFAATAN AIR KELAPA TUA MENJADI SIRUP DI DESA MAMALA, KECAMATAN LEIHITU KABUPATEN MALUKU TENGAH
Authors: Grace Sipahelut Sophia 
Published: October 2024

Potensi kelapa di Desa Mamala Kecamatan Leihitu Kabupaten Maluku Tengah cukup melimpah, namun air kelapa yang merupakan bagian dari buah kelapa jarang dimanfaatkan bahkan dibuang begitu saja, padahal air kelapa tua masih mengandung nutrisi yang bermanfaat bagi tubuh manusia. Tujuan dari kegiatan pengabdian ini adalah untuk meningkatkan pengetahuan dan keterampilan masyarakat Desa Mamala, Kecamatan Leihitu, Kabupaten Maluku Tengah tentang kandungan nutrisi air kelapa tua dan cara pembuatan sirup air kelapa. Kegiatan pengabdian kepada masyarakat ini diikuti oleh 25 orang peserta yakni ibu rumah tangga dan remaja putri. Tahapan kegiatan ini diawali dengan survei, penyuluhan, pelatihan dan evaluasi. Kegiatan penyuluhan yang dilakukan mampu meningkatkan pengetahuan masyarakat tentang kandungan nutrisi air kelapa tua dan cara pembuatan sirup air kelapa. Kegiatan pelatihan bertujuan untuk meningkatkan keterampilan masyarakat tentang pembuatan sirup air kelapa. Hasil evaluasi menunjukkan bahwa terjadi peningkatan pengetahuan masyarakat tentang kandungan air kelapa tua maupun cara pembuatan sirop air kelapa.
Development and Validation of the Asian AMD Age-Related Macular Degeneration Risk Scale
Authors: Ismayilova Inara , Korol Andrii , Aldasheva Neilya 
Published: October 2024

Introduction: This study aimed to develop a method for predicting the risk of developing macular degeneration in the early stages by facilitating prompt intervention by medical professionals.
Methods: Using a cross-sectional design, 455 age-related macular degeneration (AMD) patients from Kazakhstan were recruited via random sampling. Demographic traits, familial AMD history, medical history, and eye-related characteristics were collected through a systematic questionnaire. The patient cohort comprised 169 Caucasians and 286 Asians, with 160 males and 295 females.
Results: Notably, 117 individuals (25.7%) were classified as high AMD risk, 322 (70.8%) as moderate risk, and 16 (3.5%) as low risk. Additionally, eye-related findings revealed high-risk factors, including bright iris colors, increased UV exposure, and cataract surgery, alongside presbyopia and myopia. The study underscores the need for national/regional AMD risk stratification to inform monitoring and screening programs. Recognizing high-risk individuals holds paramount significance from both public health and therapeutic perspectives, offering opportunities for early detection and management to mitigate permanent vision loss.
Conclusions: The findings elucidate the interplay between risk factors, shedding light on their collective impact on AMD risk. Overall, this study's predictive model and risk categorization framework have substantial implications for ophthalmological practice, enabling timely preventive measures and potentially revolutionizing AMD management.
The effect of board of director diversity on company performance and the mediating role of director remuneration: Malaysia public companies’ evidence
Authors: Che Mat Noraida Adila , Maznah Mohd Salleh Sri Sarah 
Published: October 2024

Introduction: The board of director diversity plays a critical role in developing strategic options to improve company performance. The appropriate remuneration package for the director might bridge between the effectiveness of diversity of board and enhancing company performance.Objective: The study aims to examine the effect of board of director diversity on company performance, with a particular focus on the mediating role of director remuneration. Methodology: The nature of the study is quantitative. The current study focuses on the Malaysia public listed companies. The study used panel data from period 2015 to 2021 using secondary data which extracted from Bloomberg database and company annual report. The study utilized 601 sample observation. Result: Data was analysed through Stata software and the findings reveal a significant positive relationship between board diversity (gender, ethnicity, tenure) and company performance measured by Economic Value Added (EVA) and Environmental, Social and Governance (ESG) scores. Additionally, director remuneration is found to significantly mediate the impact of board diversity on EVA, although its mediation effect of ESG performance is less pronounced. These results highlight the importance of fostering diverse boards and implementing fair remuneration practices to enhance both financial and non-financial performance in companies. Conclusion: this study provides valuable insights for policymakers, stakeholders and investors aiming to improve corporate governance practices in Malaysia public listed companies
Efforts to Develop Cognitive Abilities in Children Aged 4-5 Years Using Number Wheel Media at Cahaya Utara PAUD Pawangdesa Gunjan Asri
Authors: Denda Denda , Kertadi Kertadi , Julianti Martina , Muhamad Idris 
Published: October 2024

This research aims to discuss how to improve children's cognitive development by playing with number pinwheels for students in the group (4-5) years old at Cahaya Utara Pawang PAUD. The type of observation that we used in this research was (PTK) Classroom Action Research using 2 cycles, in each cycle we held 3 meetings, the students we studied were 11 children where these participants were group A. The technique used in this research used observation and documentation Research is carried out in a systematic, empirically reflective and rational manner regarding every action that has been carried out during the research. Meanwhile, in this research, data analysis was carried out using an analysis model consisting of: Planning, Implementation, Observation and reflection. The results of research at Cahaya Utara Pawang preschool in cognitive development using number wheel media are very important because in learning activities in kindergarten an educator must be imaginative and have the ability to create a fun teaching and learning atmosphere so that students do not get bored quickly in learning. Kindergarten is an institution that is very important in developing children's cognitive abilities. As we know, this age is a golden age and will not happen again, therefore an educator must pay very careful attention.
INTEGRAÇÃO DA INTELIGÊNCIA ARTIFICIAL NO PROCESSO FARMACÊUTICO: DESAFIOS E OPORTUNIDADES
Authors: S SOUZA RONDINELI 
Published: October 2024

A integração da Inteligência Artificial (IA) no processo farmacêutico representa uma mudança transformadora na forma como os medicamentos são projetados, testados e comercializados. Tecnologias de IA, como aprendizado de máquina e processamento de linguagem natural, permitem que as empresas farmacêuticas analisem grandes conjuntos de dados, descubram padrões e tomem decisões informadas de maneira mais eficiente do que os métodos tradicionais. Um dos principais desafios nessa integração é a necessidade de dados de alta qualidade; o sucesso dos algoritmos de IA depende fortemente da precisão e abrangência das informações fornecidas. Além disso, a conformidade regulatória e a privacidade dos dados são preocupações significativas que exigem uma navegação cuidadosa. Apesar desses desafios, as oportunidades apresentadas pela IA no setor farmacêutico são substanciais. A IA pode acelerar a descoberta de medicamentos, otimizar o design de ensaios clínicos e personalizar planos de tratamento, levando a melhores resultados para os pacientes. Além disso, análises preditivas baseadas em IA podem ajudar a antecipar tendências de mercado e necessidades dos consumidores, permitindo que as empresas se mantenham competitivas. À medida que a indústria evolui, a colaboração entre as partesinteressadas—incluindo empresas de tecnologia, agências reguladoras e provedores de saúde—será fundamental para aproveitar todo o potencial da IA. Ao abraçar esse avanço tecnológico, a indústria farmacêutica pode aumentar a eficiência, reduzir custos e trazer terapias inovadoras aos pacientes mais rapidamente.
Distributed Aggregation Protocol (DAP) Primer
Authors: Tiwari Abhishek 
Published: October 2024

In last post we covered, Privacy Preserving Measurement (PPM) and discussed how Distributed Aggregation Protocol (DAP) works (see here). Today, we’ll explore how to implement a simplified version of the DAP using Python with Prio3 as our Verifiable Distributed Aggregation Function (VDAF). This implementation will support multiple clients, demonstrating how DAP can aggregate data from multiple sources while maintaining privacy.
CfP: conference “Dementia Futures”. Jan 22-24, 2025 @ University of Manchester (UK).
Authors:   CSTonline
Published: November 2024

Dementia Futures Call for Papers 22-24 January 2025 Martin Harris Centre, University of Manchester Conference organisers: MaoHui Deng, Sarah Fox, Kate Maguire-Rosier, and Réka Polonyi Cultural narratives and research around dementia are not usually focused on ideas of a future with dementia.
CfP: “Give me your best shot, pal. I can take it.”: Fight Scene Choreography in Film and TV Series. Oct 4, 2024 @ Montpellier (FR). Deadline: April 1, 2024.
Authors:   CSTonline
Published: November 2024

Montpellier, October 4, 2024 One-day symposium organized by Amandine D’Azevedo and David Roche Université Paul-Valéry Montpellier 3, Institut Universitaire de France This one-day symposium will focus on fight choreographies in films and television series.
NICE ONE!
Authors: Pixley Andrew 
Published: November 2024

So, this morning, the day has already got off to a good start with the unprompted arrival of what I like to think of as a ‘Nice one!’ e-mail. They don’t have to be long. They don’t have to be complicated. And – indeed – they were a thing taught to me in the technology field
<em>
before
</em>
we even had e-mails. I have no idea what I liked to think of them as back then.
Analisis Akuntabilitas Pengelolaan Keuangan Bumdes
Authors: Safarudin Agus 
Published: October 2024

Penelitian ini bertujuan untuk menganalisis dan mendeskripsikan akuntabilitas pengelolaan keuangan BUMDes di desa Sungai Jambat Kecamatan Sadu kabupaten Tanjung Jabung Timur. Jenis penelitian ini adalah penelitian kualitatif dengan metode analisis data menggunakan deskriptif di mana teknik pengumpulan data dilakukan dengan cara observasi, wawancara dan dokumentasi. Adapun informan dalam penelitian ini adalah kepala desa, ketua BPD, kordinator BUMDes, direktur BUMDes, sekretaris, bendahara, serta masyarakat. Hasil penelitian menunjukkan bahwa pengelolaan keuangan BUMDes Sungai Jambat yang diawali dengan tahap perencanaan yakni melakukan musyawarah, yang dihadiri ketua BPD, kepala desa, pengurus BUMDes, serta ketua RT sebagai perwakilan masyarakat, selanjutnya tahap penatausahaan, tahap pelaporan serta tahap pertanggungjawaban yang ke semua tahapan ini telah dilakukan dengan sangat baik dan mengikuti perundang-undangan yang berlaku. Dalam hal ini pengelolaan keuangan BUMDes di Desa Sungai Jambat sudah menerapkan prinsip akuntabilitas yang didukung prinsip transparansi, yang dibuktikan dengan pengurus BUMDes melengkapi papan informasi pemasukan dan pengeluaran setiap bulan, serta pelaporan keuangan tahunan dan laporan pertanggungjawaban.
IMPLEMENTASI EKONOMI MANAJERIAL PADA PERUSAHAAN MANUFAKTUR
Authors: Amalia Rosyada  , Muchammad Al Fatih  , Nico Euduard Dhani Sutanto  , Suriyanti  , Gebby Ritta Antika  
Published: October 2024

Ekonomi manajerial yaitu ilmu dan seni yang menggabungkan teori ekonomi dan teknik pengambilan keputusan. Ilmu ini bermanfaat agar sebuah organisasi dapat mencapai tujuannya secara efektif dan efisien. Tujuan penelitian adalah untuk mengetahui bagaimana PT Unilever Indonesia dapat mengelola ekonomi manajerial agar kelak sebuah perusahaan tersebut dapat diatasi dengan baik. Manfaat penelitian ini adalah untuk mendapatkan pengetahuan dan informasi sebagaimana sangat berguna bagi seorang manager untuk tau cara mengelola dan mengurangi resiko terhadap perusahaan yang akan diteliti. Dalam penelitian ini PT Unilever Indonesia dapat mengelola ekonomi manajerial dengan melakukan identifikasi resiko-resiko dari semua bidang, kemudian mengukur tingkat resiko tersebut serta membuat strategi untuk mencegah resiko-resiko yang akan terjadi dimasa mendatang.
Penyaluran Aspirasi Kaum Muslimin Di Negara Demokrasi Dalam Perspektif Islam
Authors: Muin Hijrayanti Sari 
Published: October 2024

Demokrasi merupakan pilihan sistem politik oleh banyak negara di dunia ini. Pemilihan sistem politik dalam sebuah negara telah ditetapkan oleh konstitusi negara tersebut. Berdasarkan sejarahnya demokrasi bukanlah sistem yang berasal dari ajaran Islam, ini menjadi sebuah masalah buat kaum muslimin yang menyadari bahwa semua tatanan kehidupan harus bersumber dari Islam, sehingga hal ini menyebabkan adanya fenomena kaum muslimin yang tidak ingin terlibat dan tidak ingin menggunakan hak yang telah diatur oleh undang-undang dalam agenda-agenda ataupun aktifitas politik demokrasi. Penelitian ini ingin menjawab hukum penggunaan hak penyaluran aspirasi kaum muslimin di negara demokrasi. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan yuridis normative yaitu menemukan kesesuaian antara muatan isi undang-undang yang berlaku mengenai hak warga negara di negara demokrasi dengan hukum Islam. Hasil dari penelitian ini menyebutkan bahwa penyaluran aspirasi pada sistem demokrasi yaitu ikut pemilu dan demonstrasi adalah berdasarkan pendapat ulama dengan kaidah menghindari kemudharatan yang lebih besar maka hukumnya boleh bahkan bisa pada derajat wajib
The Concept of Marriage Guardian in the Perspective of Islamic Law
Authors: Faizah Nur 
Published: October 2024

Marriage Guardian (wali nikah) is one of the pillars of marriage in Islam that must be fulfilled for marriage to be considered valid. In the perspective of Islamic law, the marriage guardian has a very important role because without the presence or permission of the guardian, the marriage can be considered invalid. Marriage guardian is generally a man who has the closest blood relationship to the prospective bride, such as a father, brother, or other relative. The main task of the guardian is to give permission or approval for the marriage of the woman he is guardian of, with the aim of protecting the rights and honor of the prospective bride and keeping the marriage in accordance with Islamic law. In the fiqh literature, there are different views among scholars regarding the type of guardian and the conditions that must be met by the guardian, such as whether guardianship must be given by the nasab guardian (blood relative) or wali hakim (legal authority) if the nasab guardian is absent. This study aims to examine the position of marriage guardians in Islamic law, by reviewing the shar'i arguments and views of various madhhabs regarding the validity of marriage and the responsibilities of guardians.