bluuebunny/crossref_metadata_2025_split huggingface dataset:
Millennials’ attitude toward advertising: an international exploratory study
Authors: Oumlil A. Ben , Balloun Joseph L. 
Published: September 2019

Purpose
Researchers emphasized that only a small effort has addressed the beliefs and attitudes of millennials toward advertising. The purpose of this study is also to respond to researchers’ recognition of the dearth of cross-national advertising and globalization studies in emerging markets. To fill this theoretical gap in the literature, this study aims to assess attitudinal differences and similarities, as well as the underlying structures of the attitude toward advertising in general (AG), of millennial consumers from developed and emerging markets (USA, UK, France, Spain and Morocco).

Design/methodology/approach
Data were obtained from millennials through self-administered survey questionnaires. It drew from findings of previous research and theoretical development by Bauer and Greyser, Pollay and Mittal, Sandage and Leckenby, Muehling, Durvasula and Netemeyer, and Andrews, Lysonski and Durvasula. Various statistical analyses were used to explore differences and similarities in AG.

Findings
The paper concludes that the two-factor solution framework of AG is inadequate. Research results also indicated that millennials from each of the five different countries studied did not indicate overwhelmingly favorable or unfavorable AG. This study found eight factors/constructs (i.e. promote bad things as good, product information, social role and image, hedonism/pleasure, good for the economy, materialism, falsity and “not interpretable”) as descriptors of the millennials from the five nations’ AG.

Research limitations/implications
The differences in advertising beliefs and attitudes among samples in the five countries studied may be because of such factors as historical values, practices and regulations. Cultural values and dimension may influence millennials’ perceived AG and need to be taken into consideration.

Practical implications
Academicians and practitioners in the advertising field need to appreciate the country’s cultural peculiarities. In understanding the advertising preferences of millennial consumers in these five markets, marketing and advertising executives may have localized their advertising messages for each studied market, resulting in different responses from these millennial consumers.

Originality/value
Millennials need not be conceptualized as a single niche market. While the focus of most of research in the determinants of AG had been within the Western business/consumer construct, the goal is to include assessment of AG in a non-Western, emerging market. This paper addresses the dearth in determinants of AG research in North Africa and other emerging markets.
Body‐wave passive seismic interferometry revisited: mining exploration using the body waves of local microearthquakes
Authors: Polychronopoulou Katerina , Lois Athanasios , Draganov Deyan 
Published: September 2019

ABSTRACTAs the global need for mineral resources is constantly rising and the exploitable concentrations of these resources tend to become increasingly complex to explore and exploit, the mining industry is in a constant quest for innovative and cost‐effective exploration solutions. In this context, and in the framework of the Smart Exploration action, an integrated passive seismic survey was launched in the Gerolekas bauxite mining site in Central Greece. A passive seismic network, consisting of 129 three‐component short‐period stations was installed and operated continuously for 4 months. The acquired data permitted detection of approximately 1000 microearthquakes of very small magnitude (duration magnitude ranging between –1.5 and 2.0), located within or at a very close distance from the study area. We use this microseismicity as input for the application of passive seismic interferometry for reflection retrieval, using the body waves (P‐ and S‐wave coda) of the located microearthquakes. We retrieve by autocorrelation zero‐offset virtual reflection responses, per component, below each of the recording stations. We process the acquired results using reflection processing techniques to obtain zero‐offset time and depth sections, both for P‐ and for S‐waves. In the context of the present work, we evaluate one of the acquired depth sections, using an existing seismic line passing through the Gerolekas passive seismic network, and we perform forward modelling to assess the quality and value of the acquired results. We confirm that passive seismic reflected‐wave interferometry could constitute a cost‐effective and environmentally friendly innovative exploration alternative, especially in cases of difficult exploration settings.
Beyond the boxes
Authors: SCOTT‐SMITH TOM 
Published: September 2019

ABSTRACTHumanitarian agencies often reach for new designs and technologies in order to meet basic human needs. In the field of emergency shelter, one of the most widely publicized new designs is the Ikea refugee shelter: a flat‐packed, mass‐produced structure that can be shipped and constructed wherever it is required. This shelter aspires to be a universal solution, but since its formal launch in 2013, it has met with criticism and many challenges in the field. Deployed in political contexts in which people have very different expectations of basic shelter, the Ikea shelter demonstrates the limitations of universal standards, the inequities of humanitarianism, and the entwinement of biopolitics and the politics of life. [humanitarianism,refugees,architecture,shelter,design,politics of life,Ikea,Sweden]
Diagnostic flowchart to estimate the morphology of left descending artery lesions by initial electrocardiogram in ST‐elevation myocardial infarction
Authors: Fujii Toshiharu , Hasegawa Misaki , Nakamura Norihito , Ikari Yuji 
Published: September 2019

AbstractBackgroundST‐segment deviations in an initial 12‐lead electrocardiogram provide anatomical information in ST‐elevation myocardial infarction (STEMI). A diagnostic flowchart was formulated to estimate the anatomical characteristics of a culprit left anterior descending artery (LAD).MethodsThe present study analyzed 252 STEMI patients whose culprit lesions were confirmed to be LAD as an observational study. LAD morphology, wrapped (n = 26) or not (n = 226), and the positional relationship to first diagonal branch (n = 162 in proximal, n = 90 in distal lesions) were assessed. Their ST‐segment deviations and such anatomical characteristics were examined.ResultsReciprocal ST depression in nonwrapped LAD was frequent in patients without diagonal branch flow (49.3%–18.8% in II, p < .01; 66.4%–36.3% in III, p < .01; 63.7%–30.0% in aVF, p < .01). ST elevation in inferior leads was the characteristics of wrapped LAD but was not the case in patients without diagonal flow (50%–0% in II, 60%–0% in III, and 60%–0% in aVF). ST elevation in lateral leads to the diagonal branch in nonwrapped LAD is more frequent for proximal than distal lesions (36.3% vs. 15.0% in I, p < .01; 50.7% vs. 16.3% in aVL, p < .01), but this was not observed for wrapped LAD (18.8% vs. 20.0% in I, p = .72; 31.3% vs. 10.0% in aVL, p = .21). Positive and negative predictive values for the diagnostic accuracy of suggested diagnostic flow based on the above results were 0.794 and 0.478, respectively.ConclusionsOur suggested diagnostic flowchart provides enough diagnostic accuracy to estimate culprit morphology.
Structural insights into polysaccharide recognition by Flavobacterium johnsoniae dextranase, a member of glycoside hydrolase family 31
Authors: Tsutsumi Kenta , Gozu Yoshifumi , Nishikawa Atsushi , Tonozuka Takashi 
Published: September 2019

Glycoside hydrolase family (GH) 31 contains a large variety of enzymes, but the major members are enzymes that act on relatively small oligosaccharides such as α‐glucosidase. Here, we determined the crystal structure of Flavobacterium johnsoniae dextranase (FjDex31A), an enzyme from F. johnsoniae that hydrolyzes a polysaccharide, dextran. FjDex31A is composed of four domains: an N‐terminal domain, a catalytic domain, a proximal C‐terminal domain, and a distal C‐terminal domain, as observed in typical GH31 enzymes. However, the architecture of active site residues in FjDex31A, other than subsite −1, is markedly different from that of other GH31 enzymes. The FjDex31A structure in complex with isomaltotriose shows that Gly273 and Tyr524, both of which interact with an α‐glucose residue at subsite −2, as well as Trp376 and Leu308‐cisGln309, are especially unique to FjDex31A. Site‐directed mutagenesis of Gly273 and Tyr524 resulted in a decrease in the hydrolysis of polysaccharides dextran and pullulan, as well as that of the disaccharide isomaltose. These results suggest that, regardless of the length of sugar chains of the substrates, binding of FjDex31A to the substrates at subsite −2 is likely to be important for its activity.DatabaseStructural data are available in the Protein Data Bank under the accession numbers 6JR6, 6JR7, and 6JR8.
Limitations of trait‐based approaches for stressor assessment: The case of freshwater invertebrates and climate drivers
Authors: Hamilton Anna T. , Schäfer Ralf B. , Pyne Matthew I. , Chessman Bruce , Kakouei Karan , Boersma Kate S. , Verdonschot Piet F. M. , Verdonschot Ralf C. M. , Mims Meryl , Khamis Kieran , Bierwagen Britta , Stamp Jen 
Published: September 2019

AbstractThe appeal of trait‐based approaches for assessing environmental vulnerabilities arises from the potential insight they provide into the mechanisms underlying the changes in populations and community structure. Traits can provide ecologically based explanations for observed responses to environmental changes, along with predictive power gained by developing relationships between traits and environmental variables. Despite these potential benefits, questions remain regarding the utility and limitations of these approaches, which we explore focusing on the following questions: (a) How reliable are predictions of biotic responses to changing conditions based on single trait–environment relationships? (b) What factors constrain detection of single trait–environment relationships, and how can they be addressed? (c) Can we use information on meta‐community processes to reveal conditions when assumptions underlying trait‐based studies are not met? We address these questions by reviewing published literature on aquatic invertebrate communities from stream ecosystems. Our findings help to define factors that influence the successful application of trait‐based approaches in addressing the complex, multifaceted effects of changing climate conditions on hydrologic and thermal regimes in stream ecosystems. Key conclusions are that observed relationships between traits and environmental stressors are often inconsistent with predefined hypotheses derived from current trait‐based thinking, particularly related to single trait–environment relationships. Factors that can influence findings of trait‐based assessments include intercorrelations of among traits and among environmental variables, spatial scale, strength of biotic interactions, intensity of habitat disturbance, degree of abiotic stress, and methods of trait characterization. Several recommendations are made for practice and further study to address these concerns, including using phylogenetic relatedness to address intercorrelation. With proper consideration of these issues, trait‐based assessment of organismal vulnerability to environmental changes can become a useful tool to conserve threatened populations into the future.
The immune response to malaria in utero
Authors: Feeney Margaret E. 
Published: September 2019

AbstractMalaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates. However, the infant immune response to malaria may be influenced by events that occur well before birth. Placental malaria infection complicates one quarter of all pregnancies in Africa and frequently results in exposure of the fetus to malaria antigens in utero, while the immune system is still developing. Some data suggest that in utero exposure to malaria may induce immunologic tolerance that interferes with the development of protective immunity during childhood. More recently, however, a growing body of evidence suggests that fetal malaria exposure can prime highly functional malaria‐specific T‐ and B‐cells, which may contribute to postnatal protection from malaria. In utero exposure to malaria also impacts the activation and maturation of fetal antigen presenting cells and innate lymphocytes, which could have implications for global immunity in the infant. Here, we review recent advances in our understanding of how various components of the fetal immune system are altered by in utero exposure to malaria, discuss factors that may tilt the critical balance between tolerance and adaptive immunity, and consider the implications of these findings for malaria prevention strategies.
Exhaustion may not be in the human B cell vocabulary, at least not in malaria
Authors: Holla Prasida , Ambegaonkar Abhijit , Sohn Haewon , Pierce Susan K. 
Published: September 2019

AbstractT cells exposed to persistent antigen in the inflammatory environment of chronic infections often show progressive loss of effector functions, high expression of inhibitory receptors and distinct transcriptional programs. T cells in this functional state are termed “exhausted” and T cell exhaustion is associated with inefficient control of infections. A remarkably similar scenario has been described for B cells during chronic infections in humans, including malaria, in which case a subpopulation of atypical memory B cells (MBCs) greatly expands and these MBCs show attenuation of B cell receptor signaling, loss of the B cell effector functions of antibody and cytokine production, high expression of inhibitory receptors and distinct transcriptional profiles. The expansion of these MBCs is also associated with inefficient control of infections. Despite the similarities with exhausted T cells we speculate that at least in malaria, atypical MBCs may not be exhausted but rather may be functional, possibly even beneficial. Our recent results suggest that we simply may not have known how to ask an atypical MBC to function. Thus, exhaustion may not be in the human B cell's vocabulary, at least not in malaria.
Individual and synergistic effects of male external genital traits in sexual selection
Authors: Rodriguez‐Exposito Eduardo , Garcia‐Gonzalez Francisco , Polak Michal 
Published: September 2019

AbstractMale genital traits exhibit extraordinary interspecific phenotypic variation. This remarkable and general evolutionary trend is widely considered to be the result of sexual selection. However, we still do not have a good understanding of whether or how individual genital traits function in different competitive arenas (episodes of sexual selection), or how different genital traits may interact to influence competitive outcomes. Here, we use an experimental approach based on high‐precision laser phenotypic engineering to address these outstanding questions, focusing on three distinct sets of micron‐scale external (nonintromittent) genital spines in maleDrosophila kikkawaiBurla (Diptera: Drosophilidae). Elimination of the large pair of spines on the male secondary claspers sharply reduced male ability to copulate, yet elimination of the other sets of spines on the primary and secondary claspers had no significant effects on copulation probability. Intriguingly, both the large spines on the secondary claspers and the cluster of spines on the primary claspers were found to independently promote male competitive fertilization success. Moreover, when large and small secondary clasper spines were simultaneously shortened in individual males, these males suffered greater reductions in fertilization success relative to males whose traits were altered individually, providing evidence for synergistic effects of external genital traits on fertilization success. Overall, the results are significant in demonstrating that a given genital trait (the large spines on the secondary claspers) can function in different episodes of sexual selection, and distinct genital traits may interact in sexual selection. The results offer an important contribution to evolutionary biology by demonstrating an understudied selective mechanism, operating via subtle trait interactions in a post‐insemination context, by which genital traits may be co‐evolving.
Increased frequency of Demodex blepharitis in rosacea and facial demodicosis patients
Authors: Sarac Gulbahar , Cankaya Cem , Ozcan Kubra Nur , Cenk Hülya , Kapicioglu Yelda Karincaoglu 
Published: September 2019

AbstractBackgroundRosacea is an inflammatory disease with 50% of ocular involvement rate. Primary demodicosis is an eruption caused by Demodex mites, and there is no data about the rate of ocular involvement in primary demodicosis.AimsIn this cross‐sectional study, it is aimed to reveal the frequency of Demodex blepharitis in rosacea and primary demodicosis patients.MethodsIn total, 58 rosacea, 33 primary demodicosis patients, and 31 healthy volunteers were included in the study. Four samples were obtained from eyelashes with a forceps and from facial skin by standardized skin surface biopsy. A positive result is described as detecting at least one Demodex mite on an eyelash or at five mites in the face. The patients were also examined by an ophthalmologist in terms of ocular involvement.ResultsBoth rosacea and primary demodicosis patients had significantly more complaints like burning and stinging in the eyes compared to the control patients (P = .001). Primary demodicosis and papulopustular rosacea patients had the highest numbers of eyelash mites, respectively, and significantly a higher rate of blepharitis than the control group.ConclusionAs a result, the Demodex count was significantly higher in the primary demodicosis and rosacea patients than the control group. We think that every Demodex‐positive patients should be evaluated for also eyelash mites to prevent a possible chronic blepharitis.
Teardowns, popups, and renovations: How does housing supply change?
Authors: Schuetz Jenny 
Published: September 2019

AbstractCities grow in layers over time. As population and land values increase, older, smaller buildings are replaced with higher density, higher value structures. However, direct costs of redevelopment and institutional barriers such as zoning may constrain replacement of older structures, leading to alternate forms of supply adjustment. In this paper, I use data on building permits in Washington DC to examine three different forms of residential investment: new construction, expansion of existing structures, and renovation. Results suggest that new construction accounts for a relatively small part of residential investment and is highly concentrated in a few neighborhoods. Expansions and alterations of existing structures are more frequent and more evenly dispersed across space. Recent increases in housing values are correlated with more new construction, but only among neighborhoods with relatively more permissive zoning. Additions and alterations are more prevalent in neighborhoods with high property values, older housing, and more restrictive zoning.
Characterization of disease resistance genes in the Brassica napus pangenome reveals significant structural variation
Authors: Dolatabadian Aria , Bayer Philipp E. , Tirnaz Soodeh , Hurgobin Bhavna , Edwards David , Batley Jacqueline 
Published: September 2019

SummaryMethods based on single nucleotide polymorphism (SNP), copy number variation (CNV) and presence/absence variation (PAV) discovery provide a valuable resource to study gene structure and evolution. However, as a result of these structural variations, a single reference genome is unable to cover the entire gene content of a species. Therefore, pangenomics analysis is needed to ensure that the genomic diversity within a species is fully represented. Brassica napus is one of the most important oilseed crops in the world and exhibits variability in its resistance genes across different cultivars. Here, we characterized resistance gene distribution across 50 B. napus lines. We identified a total of 1749 resistance gene analogs (RGAs), of which 996 are core and 753 are variable, 368 of which are not present in the reference genome (cv. Darmor‐bzh). In addition, a total of 15 318 SNPs were predicted within 1030 of the RGAs. The results showed that core R‐genes harbour more SNPs than variable genes. More nucleotide binding site‐leucine‐rich repeat (NBS‐LRR) genes were located in clusters than as singletons, with variable genes more likely to be found in clusters. We identified 106 RGA candidates linked to blackleg resistance quantitative trait locus (QTL). This study provides a better understanding of resistance genes to target for genomics‐based improvement and improved disease resistance.
Performance pay and assortative matching
Authors: Bender Keith A. , Green Colin P. , Heywood John S. 
Published: September 2019

AbstractWe show that couples sort on performance pay with dual receipt couples much more likely than predicted by random. In addition, we show that the return to performance pay appears largely invariant to whether one's spouse earns performance pay. The major exception is that among the college educated, the return to performance pay is larger for women when their spouse also receives performance pay. Thus, dual receipt households concentrate the returns to performance pay hinting that performance pay may influence the distribution of household income.
The Impact of Fact‐Based Instructions on Juror Application of the Law: Results from a Trans‐Tasman Field Study
Authors: Spivak Benjamin , Ogloff James , Clough Jonathan , Tinsley Yvette , Young Warren 
Published: September 2019

ObjectiveOver the past five decades, numerous researchers in common‐law jurisdictions have reported that jurors often fail to understand and apply the law presented to them by the trial judge. Several researchers have attempted to improve understanding of the law through revising language and utilizing instructional aides. The present study examines a novel method of instructing the jury, known as the “fact‐based” approach, which embeds legal concepts in a series of logically ordered written factual questions that the jury must answer to reach a verdict.MethodsThe study compared 287 jurors in 45 trials who received “fact‐based” instructions in New Zealand against 176 jurors in 41 trials who received standard form instructions in Australia. Participants in the study were compared on their ability to perform three tasks—selecting legal concepts in a recognition task, paraphrasing concepts in a recall task, and applying legal concepts to legally unambiguous factual scenarios.ResultsAfter controlling for trial‐related factors such as length of trial, word count, and readability of instructions, as well as the self‐reported level of education of participants, the study found that jurors receiving fact‐based directions performed significantly better on application‐based tasks but not significantly different on recall or recognition tasks.ConclusionThe findings suggest that fact‐based instructions may have utility for enhancing the jury's ability to resolve questions of fact in accordance with the law.