bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liquid crystal display and organic light-emitting diode display: present status and future perspectives
Authors: Chen Hai-Wei , Lee Jiun-Haw , Lin Bo-Yen , Chen Stanley , Wu Shin-Tson 
Published: March 2018

AbstractRecently, ‘Liquid crystal display (LCD) vs. organic light-emitting diode (OLED) display: who wins?’ has become a topic of heated debate. In this review, we perform a systematic and comparative study of these two flat panel display technologies. First, we review recent advances in LCDs and OLEDs, including material development, device configuration and system integration. Next we analyze and compare their performances by six key display metrics: response time, contrast ratio, color gamut, lifetime, power efficiency, and panel flexibility. In this section, we focus on two key parameters: motion picture response time (MPRT) and ambient contrast ratio (ACR), which dramatically affect image quality in practical application scenarios. MPRT determines the image blur of a moving picture, and ACR governs the perceived image contrast under ambient lighting conditions. It is intriguing that LCD can achieve comparable or even slightly better MPRT and ACR than OLED, although its response time and contrast ratio are generally perceived to be much inferior to those of OLED. Finally, three future trends are highlighted, including high dynamic range, virtual reality/augmented reality and smart displays with versatile functions.
Seizure Freedom in Patients with Dravet Syndrome with Contraceptives: A Case Report with Two Patients
Authors: Grothe Stefan , Kluger Gerhard , Lotte Jan 
Published: March 2018

AbstractDravet syndrome is a rare and malignant epileptic syndrome that is typically resistant to antiepileptic drugs. There is a growing interest in the antiepileptic properties of neurosteroids. Especially progesterone is known to act as an anticonvulsive agent. However, contraceptives that act as orally given neurosteroids often lead to increased seizures in women with epilepsy.We report on two girls with Dravet syndrome, who gained seizure freedom under therapy with contraceptives. The first patient received an oral contraceptive, a combination of an estrogen, and a gestagen, due to hypermenorrhea. The second received a pure gestagen implant for contraception.The antiepileptic effect of progesterone is mainly attributed to its conversion into allopregnanolone and related neurosteroids, which are positive modulators of gamma-aminobutyric acid A receptors. It is unclear whether the observed effect of these contraceptives containing synthetic progesterone derivatives may be specific for the Dravet syndrome, and it is unclear whether and how this observation can be used therapeutically.
Wieso werde ich ständig übergriffig?
Authors: Henrich Tobias 
Published: March 2018

Zusammenfassung
Protokoll systemische Fallbesprechung Im fünften Teil unserer Serie geht es um eine fremdaggressive Patientin, die um Aufmerksamkeit ringt und keine
Krankheitseinsicht zeigt. Lesen Sie, wie das Pflegeteam es schafft, mithilfe der systemischen Fallbesprechung neue Perspektiven für den Umgang mit der Patientin
zu entwickeln. Auch hier möchten wir Sie wieder einladen, sich selbst in die verschiedenen Rollen hineinzuversetzen. Fallen Ihnen weitere Lösungswege ein? Dann
schreiben Sie uns an psych.pflegeheute@thieme.de.
Die Agenten der Moral schlagen zurück. Zur Kritik des Prostituiertenschutzgesetzes
Authors: Benkel Thorsten 
Published: March 2018

ZusammenfassungDas ProstSchG von 2017 dient vordergründig Schutzzwecken, muss tatsächlich aber als politisches Konstrukt und darüber hinaus als empirieferne Konzeption
angesehen werden. Ein näherer Blick auf den Vorschriftenkanon offenbart, dass es hintergründig um eine moralische Wertung geht, die SexarbeiterInnen nicht
unterstützt, sondern ihre Tätigkeit mit institutionellen Widerständen versieht. Die in Verkleidung auftretende Zielsetzung ist ein Moralprotektionismus; er
dient nicht den Prostituierten, sondern denen, die sich von Sexarbeit gestört fühlen.
Assessment of peanut allergen Ara h1 in processed foods using a SWCNTs-based nanobiosensor
Authors: Sobhan Abdus , Oh Jun-Hyun , Park Mi-Kyung , Kim Seung Wook , Park Chulhwan , Lee Jinyoung 
Published: March 2018

Abstract
The goals of this research were to develop a rapid single-walled carbon nanotube (SWCNT)-based biosensor and to employ it to commercial food products for Ara h1 detection. The SWCNT-based biosensor was fabricated with SWCNTs immobilized with antibody (pAb) through hybridization of 1-pyrenebutanoic acid succinimidyl ester (1-PBASE) as a linker. The resistance difference (ΔR) was calculated by measuring linear sweep voltammetry (LSV) using a potentiostat. Resistance values increased as the concentration of Ara h1 increased over the range of 1 to 105 ng/L. The specific binding of anti-Ara h1 pAb to antigen including Ara h1 was confirmed by both indirect ELISA kit and biosensor assay. The biosensor was exposed to extracts prepared from commercial processed food containing peanuts, or no peanuts, and could successfully distinguish the peanut containing foods. In addition, the application of present biosensor approach documented the precise detection of Ara h1 concentrations in commercially available peanut containing foods.
Prolonged fever in peritoneal tuberculosis: A case report
Authors: Zein U , Irwandi S , Habib H , Lim H , Pasha M , Janis I , Saragih R H , Ginting Y 
Published: March 2018

Abstract
Peritoneal tuberculosis may lead to delayed diagnosis because of the nonspecific features such as fever, abdominal distension, abdominal tenderness, ascites, and weight loss. Here, wereported a case of prolonged fever and abdominal pain which was due to peritoneal tuberculosis. Initial examinations including acomplete blood test and serologic tests did not lead to the diagnosis. A final diagnosis was made by abdominal CT-scan and laparoscopy combined with histopathological studies. Antituberculous medications provided a good clinical response in this patient.
Prevalence of Schizophrenia in Idiopathic Normal Pressure Hydrocephalus
Authors: Vanhala Vasco , Junkkari Antti , Korhonen Ville E , Kurki Mitja I , Hiltunen Mikko , Rauramaa Tuomas , Nerg Ossi , Koivisto Anne M , Remes Anne M , Perälä Jonna , Suvisaari Jaana , Lehto Soili M , Viinamäki Heimo , Soininen Hilkka , Jääskeläinen Juha E , Leinonen Ville 
Published: March 2018

Abstract

BACKGROUND
Idiopathic normal pressure hydrocephalus (iNPH) is a progressive and potentially treatable neurodegenerative disease affecting elderly people, characterized by gait impairment and ventricular enlargement in brain imaging. Similar findings are seen in some patients with schizophrenia (SCZ).

OBJECTIVE
To determine the prevalence of SCZ among patients suffering from probable or possible iNPH and the specific effects of comorbid SCZ on the outcome of the cerebrospinal fluid (CSF) shunting.

METHODS
All medical records of the 521 iNPH patients in the NPH registry were retrospectively analyzed from 1991 until 2017. The prevalence of comorbidity of SCZ was determined and compared to that of general aged (≥65 yr) population in Finland.

RESULTS
We identified a total of 16 (3.1%) iNPH patients suffering from comorbid SCZ. The prevalence of SCZ among the iNPH patients was significantly higher compared to the general population (3.1% vs 0.9%, P < .001). All iNPH patients with comorbid SCZ were CSF shunted and 12 (75%) had a clinically verified shunt response 3 to 12 mo after the procedure. The CSF shunt response rate did not differ between patients with and without comorbid SCZ.

CONCLUSION
SCZ seems to occur 3 times more frequently among iNPH patients compared to the general aged population in Finland. The outcome of the treatment was not affected by comorbid SCZ and therefore iNPH patients suffering from comorbid SCZ should not be left untreated. These results merit validation in other populations. In addition, further research towards the potential connection between these chronic conditions is warranted.
Evaluating the effects of fish meal source and level on growth performance of nursery pigs1,2
Authors: Jones Aaron M , Wu Fangzhou , Woodworth Jason C , Tokach Mike D , Goodband Robert D , DeRouchey Joel M , Dritz Steve S 
Published: March 2018

Abstract
Three experiments were conducted to determine the effects of fish meal source on nursery pig growth performance. In experiment 1, 250 pigs (PIC 327 × 1,050, initially 7.1 ± 1.00 kg) were fed either a corn-soybean meal-based diet, a diet containing 8.3% enzymatically treated soybean meal (HP 300, Hamlet Protein, Findlay, OH), or diets containing 6% fish meal from one of three sources (IPC 790, The Scoular Company, Minneapolis, MN; Special Select Menhaden, Omega Proteins, Houston, TX; LT Prime Menhaden, Daybrook Fisheries Inc., New Orleans, LA; source 1, 2, and 3, respectively). In a completely randomized design, there were five pigs per pen and 10 pens per treatment with diets fed for 13 d. There was no evidence for differences in ADG or ADFI among pigs fed the three fish meal sources; however, pigs fed source 1 had marginally decreased (P = 0.068) G:F compared with pigs fed diets with other protein sources. In experiment 2, 350 barrows (DNA Line 200 × 400; initially 6.5 ± 0.90 kg) were assigned to one of seven dietary treatments including the same control diet and diets containing the three fish meal sources used in experiment 1, but fed at 3% or 6%. There were five pigs per pen and 10 pens per treatment with diets fed for 14 d. A source × level interaction (linear, P &lt; 0.05) for ADG and G:F was observed. Increasing fish meal source 1 increased ADG and G:F; however, pigs fed source 2 had improved ADG and G:F at 3%, but decreased performance at 6% compared with control pigs. Pigs fed source 3 had no further improvements in ADG or G:F beyond the 3% inclusion. Fishmeal analysis for total volatile N, and modified Torry digestibility did not appear to correspond with any growth performance differences measured in experiments 1 or 2. In experiment 3, 700 barrows (DNA Line 200 × 400, initially 6.5 ± 0.84 kg) were fed a control diet or four diets with 6% fish meal (source 3) containing either 0.87%, 8.70%, 16.52%, or 24.35% fish solubles. There were five pigs per pen and 28 pens per treatment with diets fed for 21 d. Overall, pigs fed diets with fish meal had increased (P &lt; 0.05) ADG and ADFI compared with pigs fed the control diet. There was no evidence for differences in growth performance as fish solubles increased. In conclusion, inconsistencies were observed in growth responses to different fish meal sources, but the amount of fish solubles, total volatile N, or modified Torry digestibility of fishmeal does not appear to explain these differences.
The End of Life Costs for Medicare Patients With Advanced Ovarian Cancer
Authors: Urban Renata R. , He Hao , Alfonso Raphael , Hardesty Melissa M. , Goff Barbara A. 
Published: March 2018

(Abstracted from Gynecol Oncol 2018;148:336–341)
Most patients with advanced ovarian cancer will ultimately die of the disease. End-of-life care for ovarian cancer patients is often associated with a considerable expenditure of resources and costs.
Cost-effectiveness of Treatments for Heavy Menstrual Bleeding
Authors: Spencer Jennifer C. , Louie Michelle , Moulder Janelle K. , Ellis Victoria , Schiff Lauren D. , Toubia Tarek , Siedhoff Matthew T. , Wheeler Stephanie B. 
Published: March 2018

(Abstracted from Am J Obstet Gynecol 2017;217(5):574.e1–574.e9)
In the United States, heavy menstrual bleeding accounts for one-third of all gynecology visits. Multiple treatment options exist for women with symptoms that cannot be controlled with more conservative methods such as oral contraceptives.
Clinical Profile of Children With Cerebral Palsy Born Term Compared With Late- and Post-term: A Retrospective Cohort Study
Authors: Frank R. , Garfinkle J. , Oskoui M. , Shevell M. I. 
Published: March 2018

(Abstracted from BJOG 2017;124:1738–1745)
Cerebral palsy (CP) is an early-onset nonprogressive movement disorder of cerebral origin, and preterm birth (<37 weeks' gestation) is one of the strongest predictors of CP. There exists a gap in knowledge on whether the clinical profile of children with CP born late/postterm differs from those born early/full term.
Cord Blood Banking for Potential Future Transplantation
Authors: Shearer William T. , Lubin Bertram H. , Cairo Mitchell S. , Notarangelo Luigi D. 
Published: March 2018

(Abstracted from Pediatrics 2017;140(5):e20172695)
Cord blood transplantation provides an array of treatment possibilities, from transplanting hematopoietic stem cells in children to the definitive treatment of certain hematological malignancies, immunodeficiencies, metabolic diseases, and hemoglobinopathies. Cord blood is noninvasively gathered from the placenta of newborn infants that would otherwise be discarded.
Serum Exoglycosidases in Children and Adolescents With Harmful Alcohol Use
Authors: Waszkiewicz Napoleon , Olański Witold , Chojnowska Sylwia , Kołakowska Urszula , Plewa Katarzyna , Mielech Włodzimierz , Bagniuk-Plewa Anna , Wasilewska Anna , Szulc Agata , Szajda Sławomir Dariusz , Zwierz Krzysztof 
Published: March 2018

Objective:There is a lack of accurate alcohol-use biomarkers in children/adolescents due to a short drinking duration/rapid normalization of elevated markers. We checked if lysosomal exoglycosidases, elevated earlier in binge-drinking young adults, can be applicable in children/adolescents as markers of harmful alcohol use.Methods:The serum activities (pKat/mL) of α-fucosidase (FUC), β-galactosidase (GAL), β-glucuronidase (GLU), β-hexosaminidase (HEX; its HEX A and HEX B isoenzymes), and α-mannosidase (MAN) were determined in 20 healthy controls (C) and 25 children/adolescents with harmful alcohol use (intoxicated by alcohol at hospital admission –AI1 and on the next day –AI2).Results:The serum HEX A and alanine aminotransferase (ALT) activity was significantly higher in the AI1 group than in the control. The activities of FUC, GAL, GLU, HEX B, and MAN were lower in the AI group. We found fair and poor accuracy, respectively, for increased enzymes HEX A and ALT. We found fair accuracy for decreased HEX B (AI1) and MAN (AI1), good accuracy for GLU (AI2), FUC (AI2), GAL (AI1, AI2), MAN (AI2), and excellent for FUC (AI1). Correlations were found: ALT with C-reactive protein (CRP), HEX A with white blood cell (WBC) count, blood alcohol concentration with FUC, MAN and HEX B, and WBC with FUC.Conclusions:Decreased FUC, GLU, GAL, MAN values, and especially FUC (AI1) have the potential to be markers of harmful alcohol use in children/adolescents. The raised activity of HEX A and ALT points to the need for further research to check another inflammatory agent as potential alcohol marker in children and adolescents. Samples need to be collected before intravenous fluid therapy.
Analysis of Opioid Use Following Curative Cancer Treatment at a Large Urban Safety-net Hospital
Authors: Cass Amanda S. , Alese Joyce T. , Kim Chaejin , Curry Marjorie A. , LaFollette Jennifer A. , Chen Zhengjia , Alese Olatunji B. 
Published: March 2018

Objectives:
This study examined the pattern of use and factors predicting prolonged prescription opioid medications among cancer patients following treatment with curative intent.

Materials and Methods:
Patients diagnosed with cancer over a 3-year period at a large urban safety-net hospital were included. Univariate and multivariate analyses was used to identify factors associated with continued opioid use.

Results:
Of the 199 patients included in the study, 38% continued to receive an opioid prescription well beyond the acute diagnosis and treatment phase. Mean age was 60.3 years, with a female preponderance (63%). Surgical resection only (31.6%) and the combination of surgery, chemotherapy, and radiation (19.7%) were the commonest treatment modalities. Pain-related comorbidities predating cancer diagnosis were reported in 53.3% of the patients, and about 33% were also on pain-modifying medications (odds ratio [OR], 3.58; 95% confidence interval [CI], 1.92-6.77; Fisher exact test P<0.001). Average number of prescriptions received per patient was 4.8 (range, 1 to 31), over an average of 9.5 months (range, 1.2 to 28.1 mo). Mean morphine milligram equivalents prescribed per prescription was 319 mg (range, 48 to 2475 mg). According to multivariate model, patients who received chemotherapy (OR, 7.25; 95% CI, 2.09-25.17; P=0.0018), or pain-modifying medications (OR, 4.61; 95% CI, 2.25-9.44; P<0.0001) were significantly more likely to continue to receive prescriptions for opioids.

Discussion:
Treatment with chemotherapy, pain-modifying medications, cancer stage, and interval between diagnosis and treatment are the best predictors for continuous opioid use. The current epidemic of opioid misuse and abuse makes examination current practices and identifification of areas of improvement imperative.
INTRAVITREAL GAS INJECTION WITH LASER PHOTOCOAGULATION FOR HIGHLY MYOPIC FOVEOSCHISIS
Authors: Zhu Xiaobo , Shen Peiyang , Li Chu , Li Han , Huang Hao , Shi Kangpei , Wang Lei , Zhang Xiaotong , Lu Lin 
Published: March 2018

Purpose:
To evaluate the effects of gas tamponade combined with laser photocoagulation without vitrectomy in patients with highly myopic foveoschisis.

Methods:
This retrospective noncomparative case series included 30 eyes of 23 patients with highly myopic foveoschisis who were treated by intravitreal injection of 0.5 to 0.7 mL C3F8 combined with laser photocoagulation 1 week later, and remained in the face-down position for 3 weeks. The patients were followed up for at least 6 months after the treatment. The refractive status, best-corrected visual acuity, and anatomical parameters of retina observed with the optical coherence tomography before and after the treatment were recorded.

Results:
The mean age of the 23 patients (6 men and 17 women) was 50.4 ± 15.1 years. The average follow-up duration was 20.8 ± 20.6 months. At the final follow-up, 23 eyes (76.7%) completely (17 eyes) or partially (6 eyes) resolved. Seventeen eyes had complete data of optical coherence tomography parameters, the mean central foveal thickness decreased significantly from 505.24 ± 466.22 μm to 186.41 ± 95.36 μm (P = 0.01), and the mean maximal macular thickness from 687.88 ± 397.00 μm to 313.65 ± 83.07 μm (P = 0.001). The mean final logarithm of the minimum angle of resolution best-corrected visual acuity (Snellen equivalent) of the 30 eyes ranged from 1.6 (20/800) to 0.2 (20/32), showing a slight improvement from 0.91 ± 0.44 (20/163) preoperatively to 0.90 ± 0.39 (20/160) postoperatively (P = 0.87).

Conclusion:
C3F8 tamponade combined with laser photocoagulation could be an alternative treatment for highly myopic foveoschisis.
Osteoarticular Infections Following Open or Penetrating Trauma in Children in the Post-Community-Acquired Methicillin-resistant Staphylococcus aureus Era: The Impact of Enterobacter cloacae
Authors: McNeil J. Chase , Vallejo Jesus G. , Hultén Kristina G. , Kaplan Sheldon L. 
Published: March 2018

Background:
Most cases of pediatric osteoarticular infections (OAIs) are hematogenous in nature and caused by Staphylococcus aureus. OAI in children can also occur through direct inoculation of microorganisms secondary to penetrating or open trauma. No studies in the United States have evaluated the microbiology or outcomes of trauma-related OAI (TROAI) in children in the era of community-acquired methicillin-resistant S. aureus (CA-MRSA).

Methods:
Cases were identified from the inpatient infectious diseases consultation database at Texas Children’s Hospital from January 2011 to December 2016. TROAI cases were those in which OAI developed following a clear history of penetrating trauma, open fracture, crush injury or traumatic amputation. Only cases with radiographic evidence of bone abscess, gross appearance of infection at the time of surgery and/or positive cultures from bone or joint were included. Complications included recurrence of infection, pathologic fracture or chronic osteomyelitis.

Results:
During the study period, 692 consultations for OAI were performed, with 34 meeting inclusion criteria. In 68%, at least 1 organism was isolated, and the most commonly isolated organisms were S. aureus (32% overall, 21% MRSA) and Enterobacter cloacae (24%). Polymicrobial infections occurred in 38% of patients. Eighty-five percentage of patients had at least 1 surgical procedure, and 38% underwent ≥ 2 procedures. Eighty-two percentage of patients were discharged on oral therapy. Complications developed in 15% of patients and were more commonly associated with E. cloacae (80% vs. 14%, P = 0.007) and fungi (P = 0.03).

Conclusion:
TROAI are relatively uncommon in children but cause significant morbidity. While MRSA contributes substantially to TROAI, the highly diverse microbiology emphasizes the importance of obtaining cultures for microbiologic diagnosis and management. Clinicians should be aware of the frequency of E. cloacae in TROAI and its high risk for sequelae.
Province‐wide Biliary Atresia Home Screening Program in British Columbia
Authors: Woolfson Jessica P. , Schreiber Richard A. , Butler Alison E. , MacFarlane Julie , Kaczorowski Janusz , Masucci Lisa , Bryan Stirling , Collet Jean Paul 
Published: March 2018

ABSTRACTBackground and Objectives:Biliary atresia (BA), a rare newborn liver disease, is the leading cause of liver‐related death in children. Early disease recognition and timely surgical Kasai hepatoportoenterostomy (KP) offers long‐term survival without liver transplant. Universal BA screening in Taiwan using infant stool color cards (ISCCs) has proven effectiveness. We report our experience with infant stool color card (ISCC) BA screening in a province‐wide program in British Columbia (BC). The objective of this study is to assess program performance and cost from launch April 1, 2014 to March 31, 2016.Methods:ISCCs distributed to families upon maternity ward discharge. Parents were instructed to monitor their infant's stool color for 1 month and contacted the screening center with concerns. The number of live births, ISCC distribution, BA cases, and costs were recorded. Cases with Program screen success had both acholic stool recognition (ISCC screen success) and timely referral for BA.Results:All 126 maternity units received ISCCs. Of 87,583 live births there were 6 BA cases. Of the 5 cases with ISCC Screen Success 3 had Program Screen Success. The median KP age in the program screen success and failure groups was 49 (42–52) and 116 (49–184) days, respectively. Program sensitivity was 50%, specificity 99%, positive predictive value 4%, and negative predictive value 99%. A random sample of 1054 charts at BC Children's Hospital found an ISCC distribution rate of 94%. After a phase‐in period, the annual program cost was $30,033.82, and the ISCC cost per birth was $0.68.Conclusions:The screening program has high specificity and distribution with low cost. Successful program case identification had earlier age at KP. Program modifications aim to improve sensitivity. Longer‐term studies will determine program impact on health outcomes.
Intrauterine Device Use and Cervical Cancer Risk: A Systematic Review and Meta-analysis
Authors: Cortessis Victoria K. , Barrett Malcolm , Wade Niquelle Brown , Enebish Temuulen , Perrigo Judith L. , Tobin Jessica , Zhong Charlie , Zink Jennifer , Isiaka Vanessa , Muderspach Laila I. , Natavio Melissa , McKean-Cowdin Roberta 
Published: March 2018

(Abstracted from Obstet Gynecol 2017;130:1226–1236)
The third most common malignancy among women worldwide is cervical cancer. Control relies primarily on screening to detect premalignant cervical lesions, which is followed by their removal.