bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hollow Bismuth Nanoparticle-Loaded Gelatin Hydrogel Regulates M2 Polarization of Macrophages to Promote Infected Wound Healing
Authors: Lv Dongming , Xu Zhongye , Yang Hao , Rong Yanchao , Zhao Zirui , Hu Zhicheng , Yin Rong , Guo Rui , Cao Xiaoling , Tang Bing 
Published: October 2024

Open wounds face severe bacterial infection, which affects the quality of healing. Photothermal antimicrobial therapy has received increasing attention as a broad-spectrum antimicrobial treatment that can avoid drug resistance. A variety of metallic materials have been used in the development of photothermal agents. However, there are few studies on bismuth as a photothermal agent and its use in tissue repair, so there is still a lack of clear understanding of its biomedical function. Here, a hollow bismuth nanosphere prepared from bismuth metal was developed for drug loading and photothermal antibacterial effect. The photothermal conversion efficiency of the hollow bismuth spheres reached 16.1%, and the bismuth-loaded gelatin-oxidized dextran (ODex)-based hydrogel achieves good antibacterial effects both in vivo and in vitro. The bismuth-loaded hydrogel can also promote the angiogenesis of human umbilical vein endothelial cells (HUVECs) and improve the proliferation of human keratinocytes cells (HaCaT) and the quality of wound healing. This discovery provides a new idea for the application of metal bismuth in the field of tissue repair and regeneration.
ТАЛЫШИНСКИЙ АБАС МЕХТИ ОГЛЫ (К 100-летию со дня рождения)
Authors: Р.Е. Калинин , В.А. Кирюшин , Н.А. Козеевская 
Published: October 2024

Статья посвящена 100-летию со дня рождения доктора медицинских наук, профессора А.М.Талышинского. Потомок Ленкоранских (Талышских) ханов, Абас Мехти оглы Талышинский – является основоположником рязанской школы фундаментальной оториноларингологии, основателем первой в Рязани оториноларингологической клиники с полным набором операций, в т.ч. онкологических. Он первым в СССР использовал в своей работе метод общего обезболивания при амбулаторных операциях, разработал и получил патент на роторасширитель, который применяется в практике до настоящего времени и носит его имя. Профессор А.М.Талышинский разработал метод хирургического лечения храпа. Именно в Рязани в 1967 году была выполнена первая в Советском Союзе успешная операция по лечению этой патологии.
A descendant of the Lenkoran (Talysh) khans, Abas Mehdi Ogly Talyshinsky is the founder of the Ryazan school of fundamental otorhinolaryngology, the founder of the first otorhinolaryngology clinic in Ryazan with a full range of ENT operations, including oncology. He was the first in the Soviet Union to use in his practice the method of general anesthesia for outpatient operations, developed and received a patent for a mouth dilator, which is still in use and bears his name. Professor A.M. Talyshinsky developed a method of surgical treatment of snoring. It was in Ryazan in 1967 that the first such operation in the USSR was carried out.
Məqalə tibb elmləri doktoru, professor A.M.Talışınskinin anadan olmasının 100-illiyinə həsr edilir. Ryazan fundamental otorinolarinqologiya məktəbinin banisi, Lənkəran (Talış) xanlarının nəslindən olan Abas Mehdi oğlu Talışinski Ryazan şəhərində ilk LOR əməliyyatları, o cümlədən onkoloji əməliyyatlar icra edilən ilk otorinolarinqologiya klinikasının yaradıcısıdır. O, Sovet İttifaqında ilk dəfə olaraq ambulator əməliyyatlar üçün ümumi anesteziya üsulunu öz praktikasında tətbiq etmiş, hələ də istifadə olunan və onun adını daşıyan ağız dilatatoru işləyib hazırlamışdır. A.M.Talışınskinin bu yeniliyi patentə layiq görülmüşdür. Professor A.M.Talışinski xoruldamanın cərrahi müalicəsi üsulunu işləyib hazırlamışdır. SSRİ-də ilk belə əməliyyat məhz 1967-ci ildə Ryazanda həyata keçirilib.
GAMBARAN KARAKTERISTIK PASIEN FISTULA PERIANAL DI RS HJ. BUNDA HALIMAH BATAM PERIODE 2022-2023
Authors: Muhammad Azmi Fanany  , Khalikul Razi  , Kiki Zulfikri  
Published: October 2024

Fistula perianal merupakan sebuah saluran yang terbentuk di antara kanalis analis dan rektum dengan kulit di sekitar anus. Kondisi patologis ini paling sering terjadi akibat ulserasi abses atau drainase insisi di sekitar anus dan rectum. Diketahui terdapat 20.000 hingga 25.000 kasus fistula perianal baru di Amerika Serikat setiap tahunnya. Sebagian besar (hingga 90%) kasus fistula ani adalah idiopatik. Beberapa kasus fistula perianal dihubungkan dengan kondisi lainnya seperti penyakit Crohn, tuberkulosis, hidradenitis supuratif, dan riwayat operasi sebelumnya ataupun radioterapi. Fistula ani tidak akan sembuh tanpa intervensi, dan kegagalan pengobatan dapat mendukung progresifitas penyakit. Komplikasi yang mungkin terjadi setelah dilakukan pembedahan pada fistula perianal antara lain yaitu kekambuhan fistula, inkontinensia, luka drainase kronis, dan striktur anus. Mengingat komplikasi yang sangat mungkin terjadi pada pasien dengan fistula perianal, maka peneliti tertarik untuk melakukan penelitian tentang gambaran karakteristik pasien fistula perianal di RS Hj. Bunda Halimah Batam Periode 2022-2023. Didapatkan sampel sebanyak 14 orang, pada penelitian didapatkan bahwa pasien fistula perianal terjadi 3 hingga 4 kali lebih sering pada laki-laki dibanding perempuan di RS Hj. Bunda Halimah periode 2022-2023. Berdasarkan data yang diperoleh dalam penelitian ini, diketahui bahwa jumlah pasien yang berusia antara rentang usia terbanyak adalah 30-39 tahun, diikuti oleh usia 40-49 tahun, kemudian usia >50 tahun. Berdasarkan data yang diperoleh bahwa jenis tindakan terbanyak adalah fistulotomi dibanding dengan fistulectomi.

Kata kunci: Fistula Perianal, Karakteristik, Komplikasi
The Reliability of YouTube as an Information Resource for Parents About Retinopathy of Prematurity
Authors: Alacamli Goksu , Yakar Konuralp 
Published: October 2024

Purpose
To investigate the quality and reliability of YouTube videos about retinopathy of prematurity (ROP) to direct parents of infants with the disease to access more accurate content.

Methods

The term “retinopathy of prematurity” has been searched on YouTube containing all of the videos between January 2 and February 2, 2024. The first 200 videos were evaluated by two ophthalmologists. Duplicated-split videos, videos shorter than 60 seconds, videos presented in languages other than English or with an incomprehensible accent, and videos unrelated to ROP were excluded. Video uploaders, types, continental origins, durations, and viewer interactions were noted. DISCERN, The
Journal of the American Medical Association
(JAMA), and the Global Quality Score (GQS) scoring systems were used to evaluate the quality of the videos.

Results
The mean quality of all videos was poor in all scoring systems. Academic societies and medical institutes scored highest in video uploaders, followed by physicians; patient experience videos had the lowest quality. Of the video types, the medical education seminars were of the highest quality. Although a strong positive correlation was detected between video duration and video quality, this same strong correlation was not observed between viewer interactions and video quality. There was no significant difference between video origins in terms of video quality.

Conclusions
It would be wiser to direct the parents of patients with ROP to watch longer videos uploaded by the academic community, medical institute, or physicians, and to watch the medical training seminars. Also, it might be important to warn them not to take user interactions too seriously.

[
J Pediatr Ophthalmol Strabismus
. 2025;62(1):42–49.]
El cristianismo entre ascética y mística en Las confesiones de la carne. Reflexiones de un patrólogo
Authors: Morales Xavier 
Published: October 2024

Para el especialista de la historia del cristianismo antiguo, en su opus posthumum, Les aveux de la chair, Michel Foucault tiende a retener solo los elementos del cristianismo que hacen de él una institución ética. Ahora bien, entre la fecha de composición de Las confesiones de la carne (1982) y la muerte de Foucault (1984), la investigación sobre la parrhesia abrió un espacio para otra manera de pensar el cristianismo, más allá de lo ético, algo similar a “la forma del otro mundo y de la vida otra” con la que Foucault describe al cinismo en sus últimas palabras escritas, y deja prever una bipolaridad ascética y mística en la “construcción del sujeto moderno”. Por lo tanto, es necesario releer Las confesiones de la carne a partir de las últimas reflexiones de El Coraje de la verdad.
Effectiveness of Scientific Calculators’ Usage in the Teaching and Learning of Grade 11 Parabola Functions to Improve Learner Performance
Authors: Ogunsipe Olugbenga Adebayo , Makgakga Tšhegofatšo Phuti 
Published: October 2024

The use of scientific calculators in teaching parabola functions has been shown to have significant effect in learner performance. This study examined the effectiveness of scientific calculators’ usage in the teaching and learning of Grade 11 parabola functions to improve learner performance. Bandura’s observational learning theory underpinned this study. A non-equivalent quazi-experimental design was espoused to collect data from the experimental and control groups. A pre-test and a post-test were administered to both experimental group and control group in the same day and at the same time, to avoid contamination of results. Wilcoxon-Rank sum test was used to determine the significant difference between the two study groups. The results showed that the experimental group performed significantly better than the control groupin the post-test after the implementation of scientific calculators in teaching parabola functions. The study suggests that scientific calculators can be used to teach parabola functions to improve learner performance and advance teacher content knowledge, pedagogical content knowledge and professional development.
Mekanisme Online Dispute Resolution Melalui Arbitrase dalam Penyelesaian Sengketa Konsumen di Sektor Jasa Keuangan
Authors: Indriyanie Dwi 
Published: October 2024

Penyelesaian sengketa konsumen di sektor jasa keuangan harus memenuhi prinsip-prinsip penyelesaian sengketa diantaranya adalah aksesibilitas, keadilan, independen dan penyelesaian yang efektif dan efisien. Terhadap pemenuhan prinsip aksesibilitas dan penyelesaian sengketa yang efektif dan efisien maka salah satu solusi yang ada adalah melalui penyelesaian sengketa dalam jaringan (daring) atau yang lebih dikenal dengan istilah online dispute resolution. Dengan pekembangan di industri jasa keuangan khususnya terkait pemanfaatan teknologi maka tidak dapat dipungkiri kebutuhan penyelesaian sengketa yang efektif dan efisien tersebut sebagai upaya perlindungan konsumen. Di sektor jasa keuangan, perlindungan konsumen merupakan suatu hal yang sangat penting, keberadaan konsumen yang memanfaatkan produk jasa keuangan merupakan roda penggerak terhadap kegiatan proses bisnis di sektor jasa keuangan. Namun perjanjian yang dibuat antara pelaku jasa keuangan dengan konsumen dalam pelaksanaannya seringkali menimbulkan perselisihan yang berujung pada sengketa yang tidak dapat diselesaikan melalui internal dispute resolutions. Sehingga diperlukan upaya lain untuk menyelesaikan sengketa tersebut baik melalui jalur litigasi atau non-litigasi dengan melalui lembaga alternatif penyelesaian sengketa. POJK 61/POJK.07/2020 menjadi dasar bagi Lembaga Alternatif Penyelesaian Sengketa Sektor Jasa Keuangan (LAPS SJK) menjalankan tugas sebagai lembaga alternatif penyelesaian sengketa di sektor jasa keuangan Indonesia. Dalam penelitian ini dibahas mengenai mekanisme online dispute resolutions melalui arbitrase dalam penyelesaian sengketa di sektor jasa keuangan melalui LAPS SJK dengan menggunakan metode penelitian yuridis normatif yaitu penelitian hukum yang dilakukan dengan meneliti bahan pustaka dan menelaah peraturan perundang-undangan yang berkaitan dengan permasalahan. Arbitrase merupakan salah satu layanan yang ditawarkan oleh LAPS SJK yang dapat dipilih oleh para pihak melalui mekanisme online dispute resolutions untuk menyelesaikan sengketa di sektor jasa keuangan yang terjadi
<b>The Potential Effectiveness of an Ancient Chinese Herbal Formula Yupingfengsan for the Prevention of COVID-19: A Systematic Review</b>
Authors: Yang Xin , Tian Rong , Shi Catherine , Wang Alan 
Published: October 2024

The COVID-19 has been spreading all over the world, and human health is at stake. Conventional medicine played an important role in the treatment and syndrome relief, while there is limited research evidence to support any prevention or antiviral treatment for COVID-19. Yupingfengsan is a classic formula with the effect of replenishing qi, consolidating exterior, and arresting sweating. Yupingfengsan has been widely used to treat various diseases in China and Southeast Asia for hundreds of years. Accumulating evidence suggests that YPFS has both immune-regulatory and anti-virus effects clinically, but leaving the mechanism elusive. In this paper, we reviewed the recent progress of Yupingfengsan in immune-regulatory and anti-virus activities, including the effect on mucosal immunity, biological antagonism, macrophages, adaptive immunity, and natural killer cells. From this systematic review, we speculate that YPFS can play an effective role in the prevention of SARS-CoV-2, but further experimental studies are expected to investigate the specific mechanisms. This review suggests an alternative direction for the prevention of COVID-19.

Received: 12 July 2024 | Revised: 18 September 2024 | Accepted: 21 October 2024

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.

Author Contribution Statement
Xin Yang: Methodology, Formal analysis, Investigation, Resources, Writing - original draft, Visualization. Rong Tian: Conceptualization, Methodology, Formal analysis, Investigation, Writing - original draft, Writing - review & editing, Supervision, Funding acquisition. Catherine Shi: Conceptualization, Methodology, Formal analysis, Investigation, Writing - original draft, Writing - review & editing. Alan Wang: Conceptualization, Methodology, Formal analysis, Investigation, Resources, Writing - original draft, Writing - review & editing, Supervision.
Die Maisgemengelage
Authors: Schaal René 
Published: October 2024

Frankfurt a.M. Mais im Gemenge erfreut sich wachsender Beliebtheit. So wird Mais in Kombination mit einem Mischungspartner vorzugsweise in Veredelungsregionen, aber auch in Gebieten mit hohem Maisanteil wie etwa in Nord- und Westdeutschland, Bayern und Sachsen, zunehmend in Fruchtfolgen integriert.
Effect of agriculture on economic growth in Algeria during the period 1991–2022
Authors: Mostefai Yassine 
Published: October 2024

Purpose. This paper aimed to study the impact of both agricultural value-added and agricultural labour on the economic growth of Algeria (represented by the real Gross Domestic Product – GDP) during the period 1991–2022, using the co-integration method according to the bounds approach known as the Autoregressive Distributed Lag modeling (ARDL).
Results. The study revealed a relationship between real agricultural value-added and real GDP in both the short and long terms. However, the impact ratio in the long term is somewhat weak, reflecting the weakness of agricultural production in contributing to total output formation and economic growth. Additionally, agricultural employment only affects real GDP in the long term. The error correction coefficient is negative and significant, with the speed of adjustment towards equilibrium in the long-term reaching approximately 52.19 % (about one year and 10 months).
Scientific novelty. This study highlights the great importance of the agricultural sector as one of the solutions to economic diversification in order to achieve economic development in Algeria – a country that has suffered and continues to suffer from economic dependence on the hydrocarbon industry. However, this study stands out from previous research by addressing various programs and reforms implemented in the agricultural sector during the study period. Moreover, it measures the impact of the agricultural sector on economic growth by creating a logarithmic model with two main variables: agricultural value-added and agricultural employment, both of which effectively contribute to increasing agricultural production and thus economic growth.
Practical value. This study emphasises the need for the government to prioritise and improve agriculture to move towards smart agriculture and reclaim wastelands. At the same time, the government must allocate new programmes to develop the agricultural sector and activate workers to increase agricultural productivity in order to achieve food security and transform the country towards a more prosperous and sustainable future.
Extreme Saharan dust events expand northward over the Atlantic and Europe, prompting record-breaking PM10 and PM2.5 episodes
Authors: Rodríguez Sergio , López-Darias Jessica 
Published: October 2024

Abstract. Unprecedented extreme Saharan dust (duxt) events have recently expanded northward from subtropical NW Africa to the Atlantic and Europe, with severe impacts on the Canary Islands, mainland Spain and continental Portugal. These six historic duxt episodes occurred on 3–5 and 22–29 February 2020, 15–21 February 2021, 14–17 January 2022, 29 January–1 February 2022, and 14–20 March 2022. We analyzed data of 341 governmental air quality monitoring stations (AQMSs) in Spain (330) and Portugal (11), where PM10 and PM2.5 are measured with European norm (EN) standards, and found that during duxt events PM10 concentrations are underestimated due to technical limitations of some PM10 monitors meaning that they can not properly measure extremely high concentrations. We assessed the consistency of PM10 and PM2.5 data and reconstructed 1690 PM10 (1 h average) data points of 48 and 7 AQMSs in Spain and Portugal, respectively, by using our novel “duxt-r” method. During duxt events, 1 h average PM10 and PM2.5 concentrations were within the range 1000–6000 µg m−3 and 400–1200 µg m−3, respectively. The intense winds leading to massive dust plumes occurred within meteorological dipoles formed by a blocking anticyclone over western Europe and a cutoff low located to the southwest, near the Canary Islands and Cape Verde, or into the Sahara. These cyclones reached this region via two main paths: by deviating southward from the Atlantic mid-latitude westerly circulation or northward from the tropical belt. The analysis of the 2000–2022 PM10 and PM2.5 time series shows that these events have no precedent in this region. The 22–29 February 2020 event led to (24 h average) PM10 and PM2.5 concentrations within the range 600–1840 and 200–404 µg m−3, respectively, being the most intense dust episode ever recorded on the Canary Islands. The 14–20 March 2022 event led to (24 h average) PM10 and PM2.5 values within the range 500–3070 and 100–690 µg m−3 in southeastern Spain, 200–1000 and 60–260 µg m−3 in central Spain, 150–500 and 75–130 µg m−3 in the northern regions of mainland Spain, and within the ranges 200–650 and 30–70 µg m−3 in continental Portugal, respectively, being the most intense dust episode ever recorded in these regions. All duxt events occurred during meteorological anomalies in the Northern Hemisphere characterized by subtropical anticyclones shifting to higher latitudes, anomalous low pressure expanding beyond the tropical belt and amplified mid-latitude Rossby waves. New studies have reported on recent record-breaking PM10 and PM2.5 episodes linked to dipole-induced extreme dust events from North Africa and Asia in a paradoxical context of a multidecadal decrease in dust emissions, a topic that requires further investigation.
Simulation-based inference for parameter estimation of complex watershed simulators
Authors: Hull Robert , Leonarduzzi Elena , De La Fuente Luis , Viet Tran Hoang , Bennett Andrew , Melchior Peter , Maxwell Reed M. , Condon Laura E. 
Published: October 2024

Abstract. High-resolution, spatially distributed process-based (PB) simulators are widely employed in the study of complex catchment processes and their responses to a changing climate. However, calibrating these PB simulators using observed data remains a significant challenge due to several persistent issues, including the following: (1) intractability stemming from the computational demands and complex responses of simulators, which renders infeasible calculation of the conditional probability of parameters and data, and (2) uncertainty stemming from the choice of simplified representations of complex natural hydrologic processes. Here, we demonstrate how simulation-based inference (SBI) can help address both of these challenges with respect to parameter estimation. SBI uses a learned mapping between the parameter space and observed data to estimate parameters for the generation of calibrated simulations. To demonstrate the potential of SBI in hydrologic modeling, we conduct a set of synthetic experiments to infer two common physical parameters – Manning's coefficient and hydraulic conductivity – using a representation of a snowmelt-dominated catchment in Colorado, USA. We introduce novel deep-learning (DL) components to the SBI approach, including an “emulator” as a surrogate for the PB simulator to rapidly explore parameter responses. We also employ a density-based neural network to represent the joint probability of parameters and data without strong assumptions about its functional form. While addressing intractability, we also show that, if the simulator does not represent the system under study well enough, SBI can yield unreliable parameter estimates. Approaches to adopting the SBI framework for cases in which multiple simulator(s) may be adequate are introduced using a performance-weighting approach. The synthetic experiments presented here test the performance of SBI, using the relationship between the surrogate and PB simulators as a proxy for the real case.
Crowd-Sourced Assessment of Laparoscopic Surgical Skills for Ob/Gyn Residents
Authors: Clarke Bayley , Tavcar Jovana , Hazen Nicholas , Robinson James 
Published: October 2024

Importance Feedback is an essential part of graduate medical education. With increasing demands on time and fewer opportunities for formal feedback in residency, there is an increasing need for objective and actionable feedback. Objective To understand how the Crowd-Sourced Assessment of Technical Skills (CSATS) assessment of residents’ laparoscopic skills compares with the current faculty assessment in an obstetrics/gynecology residency program. Design, Setting, and Participants This was a prospective educational intervention study involving residents from a single academic obstetrics/gynecology residency program at a large tertiary teaching hospital. Individual performance videos of hysterectomies, myomectomies, and endometriosis resections were recorded and uploaded to the CSATS database where they were analyzed. Formal written feedback reports from the CSATS system were sent to the residents. Residents then completed a survey addressing satisfaction, timeliness, and utility of the CSATS feedback method overall and in comparison with the residency’s in-person feedback and with the standard written, electronic feedback evaluation. Results A total of 16 residents submitted 65 videos of operations. Overall comparison of CSATS vs faculty evaluation was equivalent. Residents found that CSATS response time was slower than receiving in-person feedback from faculty. When comparing CSATS with the standard feedback form, residents felt strongly that CSATS was superior for both surgical skill feedback and procedure evaluation, with both categories having a mean top score. When comparing low-volume CSATS utilization vs high-volume CSATS utilization, there were no statistical differences. Overall, residents reported high satisfaction with CSATS evaluation. Conclusions Residents were generally satisfied with CSATS as an overall feedback tool. CSATS could be a possible addition to help improve resident education.