bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexual dysfunction among long‐term survivors of Hodgkin lymphoma
Authors: Hanzlik Emily , Sabin Noah D. , Yoshida Tomoko , Delaney Angela , Xie Lu , Darji Himani , Srivastava Deokumar , Mulrooney Daniel A. , Hudson Melissa M. , Krull Kevin R. , Khan Raja B. 
Published: November 2024

AbstractBackgroundSurvival rates from childhood cancer continue to increase, with an ongoing interest in long‐term survivorship. Although infertility and gonadal failure are well recognized in Hodgkin lymphoma (HL) survivors, sexual dysfunction is less studied. The objective of this study was to compare the prevalence of sexual dysfunction in HL survivors with that in matched community controls.MethodsLong‐term survivors of HL (n = 186; female, 51.61%; mean age at diagnosis. 14.41 years [range, 3.01–22.60 years]; current mean ± standard deviation age, 36.73 ± 7.93 years) and matched community controls (n = 182; female, 50.55%; mean ± standard deviation age, 36.41 ± 9.02 years) completed a comprehensive, in‐person clinical assessment, laboratory battery, and the International Index of Erectile Function or the Female Sexual Function Index questionnaire.ResultsMale survivors had increased levels of erectile dysfunction (18.89% vs. 6.67%; p = .0239) but indicated no difference in sexual desire. Female survivors had a higher prevalence of sexual dysfunction compared with female controls (46.88% vs. 15.22%; p < .0001) and an increased prevalence of moderate‐to‐severe loss of sexual desire (38.04% vs. 23.26%; p = .0361). Female survivors with sexual dysfunction indicated increased levels of anxiety (p = .0184), depression (p = .0153), and worse physical and mental health (p = .0141 and p = .0419, respectively). Male survivors with erectile dysfunction had higher rates of anxiety and impaired physical health (p = .0147 and p = .0266, respectively).ConclusionsSexual dysfunction was prevalent in this childhood and adolescent Hodgkin lymphoma survivor cohort and was associated with effects on quality of life. Health care providers must recognize the need for screening and intervention in this group to hopefully contribute to improved overall quality of life.
How certified benefit corporations contribute to corporate social responsibility disclosure: Empirical evidence from Italy
Authors: De Luca Roberto , Sessa Maria Rosaria , Esposito Benedetta , Malandrino Ornella 
Published: November 2024

AbstractThis paper explores the extent to which Italian Benefit Corporations which have achieved B‐Corp Certification disclose Corporate Social Responsibility (CSR) practices through their corporate websites, thus developing a disclosure index. The research also aims to analyse the correlation between the size of companies, non‐financial performance, financial results and CSR actions. Stakeholder theory and legitimacy theory were used to provide a theoretical explanation of the potential relationship among the investigated variables. Our findings reveal a positive association between firm size and CSR disclosure, while the impact of financial performance is positive but not statistically significant. Moreover, non‐financial performance significantly influences CSR disclosure levels. These results can guide companies in enhancing CSR disclosure to bolster stakeholder legitimacy and competitive advantage in sustainability‐aware markets. Notably, this study represents a novel examination of online CSR disclosure among Certified Benefit Corporations, filling a gap in the existing literature.
Intermolecular Carbanion Attack on Nitro vs. Carbonyl Group: Experimental and Computational Studies
Authors: Biró Krisztián , Nyerges Miklós , Pápai Imre , Csókás Dániel 
Published: November 2024

AbstractHighly efficient one‐pot synthesis of a series of indeno[2,1‐b]quinolin‐6‐ones 10 and indolo[1,2‐b]isoquinoline‐6,12‐diones 12 is portrayed from easily accessible starting materials such as indan‐1‐ones 7 and 2‐nitrobenzaldehydes 9. The reaction mechanism studies by control experiments and computational analysis reveal that the reactions are initiated by attack of a conjugate base of indanones 7 to the aldehyde group or the adjacent nitro group of 2‐nitrobenzaldehydes 9 followed by intramolecular cyclization involving a second anion to furnish the appropriate products. The heterocyclic compounds were obtained in moderate to good yields.
Examining the Effect of Parental COVID‐19 Vaccination Prior to Birth and the Association Between COVID‐19 and Cancer in Children Under Six
Authors: Behnaz Aflatoonian , Hossein Mirzaei , Morteza Hashemian , Hassanidarmian Gholamreza , Susefidi Zahra Mirzayi 
Published: November 2024

ABSTRACTIntroductionThe biology of COVID‐19 has intricate links to childhood cancer, exacerbated by pandemic disturbances. This research aims to explore the association between childhood cancer in children under 6 years old and COVID‐19 immunisation, in addition to the effects of vaccination on parents before delivery.MethodThe study employs a case‐control approach, gathering informed consent and matching factors like age, marital status, and socioeconomic status between cases and controls. A survey was distributed, culminating in 191 children under six, with data from 136 diagnosed cancer cases collected in 2023, adhering to methodological standards in epidemiological research. The analysis utilised SPSS28, employing chi‐square testing and logistic regression.ResultChi‐square testing confirmed a significant rise in childhood cancer rates post‐COVID‐19 pandemic compared to pre‐pandemic rates. Key factors influencing cancer incidence include the mother's age at childbirth, parental vaccination history before pregnancy, maternal vaccination details during pregnancy, the child's COVID‐19 infection status, and maternal marriage age. Notably, younger mothers faced higher COVID‐19 infection risks, but vaccination appears to mitigate paediatric cancer risk.ConclusionThe post‐pandemic surge in childhood cancer underscores a complex interplay of early exposures and maternal viral infections. Emphasising vaccination's protective effects before and during pregnancy, the study advocates integrating vaccination into maternal health programs. Public health measures should promote immunisation and address socioeconomic inequalities to lower paediatric cancer risk, aligning with previous studies linking parental health behaviours to childhood cancer incidence.
The Domestic Transition: Progress Towards Decent Living of Households in Low and Middle‐Income Countries
Authors: Schilpzand Rutger , Smits Jeroen 
Published: November 2024

ABSTRACTOver the past decades, households have gradually increased their ownership of goods that make life easier and more comfortable, such as furniture, TVs, kitchen supplies, phones, (motor)bikes, and cars. We refer to this development, in which households move from having few durable assets to having many, as the domestic transition. In this study, we argue that this transition reflects the rise towards what could be called a decent standard of living. While this standard has been reached decades ago in affluent societies, the domestic transition has hardly started in the poorest countries. The current paper aims to assess the status of the domestic transition at the level of subnational regions within low‐ and middle‐income countries and to examine how variations in its pace relate to these regions' socioeconomic, demographic, and cultural characteristics. Our analyses reveal that the domestic transition in these regions follows an S‐shaped curve and that the speed of the transition is faster in wealthier, more educated, and urbanised regions with smaller dependent populations.
CD1530, selective RARγ agonist, facilitates Achilles tendon healing by modulating the healing environment including less chondrification in a mouse model
Authors: Yimiti Dilimulati , Uchibe Kenta , Toriyama Minoru , Hayashi Yuta , Ikuta Yasunari , Nakasa Tomoyuki , Akiyama Haruhiko , Watanabe Hitomi , Kondoh Gen , Takimoto Aki , Shukunami Chisa , Adachi Nobuo , Miyaki Shigeru 
Published: November 2024

AbstractHeterotopic ossification (HO) in Achilles tendon often arises due to endochondral ossification during the healing process following trauma. Retinoic acid receptor γ (RARγ) plays a critical role in this phenomenon. This study aims to elucidate the therapeutic effects of CD1530, an RARγ selective agonist, along with the contributing cells, in Achilles tendon healing, utilizing a cell lineage tracing system. Local injection of CD1530 facilitated histological tendon healing by inhibiting chondrification in a mouse Achilles rupture model. Resident Scleraxis (Scx)+ cells in Achilles tendon were not found to be actively involved in HO or　tendon healing following injury. Instead, these processes were primarily driven by tendon stem/progenitor cells (TSPC)‐like cells. Furthermore, an in vitro assay revealed that CD1530 attenuated inflammation in injured Achilles tendon‐derived tendon fibroblasts (iATF) and inhibited the chondrogenesis of iATF. This dual effect suggests the potential of CD1530 in effectively modulating the healing environment during tendon healing. Together, the present study demonstrated that the local administration of CD1530 accelerated tendon healing by modulating the healing environment, including reducing chondrification via targeting TSPC‐like cells in a mouse Achilles tendon rupture model. These results suggest that CD1530 may have the potential to be a novel tendon therapy that offers benefits via the inhibition of chondrogenesis.
High‐Resolution X‐Ray Imaging With 0D Organic–Metal Halide Scintillator Featuring Reversed Exciton Trapping
Authors: Qian Rui‐Xuan , Lu Jian , Cui Meng , Wang Shuai‐Hua , Wang Peng‐Kun , Li Bao‐Yi , Zheng Fa‐Kun , Guo Guo‐Cong 
Published: November 2024

AbstractScintillators, essential for applications in nuclear medicine, radiation detection, and industrial inspection, convert high‐energy radiation into visible light. Manganese (Mn)‐based inorganic–organic hybrid materials are distinguished by their thermal stability, mechanical strength, and flexibility. However, the effects of temperature on Mn(II)‐based hybrid scintillators have not been clearly analyzed, making the elucidation of their temperature‐dependent luminescence mechanisms particularly important. A notable advancement is the synthesis of Mn‐1 nanocrystals (NCs) using methyltriphenylphosphonium chloride (mtppCl) and MnCl₂. These NCs exhibit distinctive temperature‐dependent photoluminescence luminescence: the intensity decreases from 77 to 150 K but paradoxically increases at higher temperatures due to anomalous thermal exciton behavior in the [MnCl₄]2⁻ tetrahedra. Besides, Mn‐1 NCs achieve a detection limit of 1.01 µGyair/s, surpassing medical diagnostic standards and outperforming commercial scintillators such as Bi₄Ge₃O₁₂ (BGO). Additionally, they show exceptional stability under continuous irradiation and can be incorporated into a flexible scintillating film with a resolution of 11.3 lp/mm at an MTF of 0.2. The current study has further refined the luminescence mechanism of Mn(II)‐based materials and optimizes their properties for a wider range of applications.
In Situ Forming Injectable Gelatin‐Based Antibacterial Bioadhesives for Preventing Postoperative Leakage and Abdominal Adhesions
Authors: Hu Shibo , Duan Wanglin , Jin Xianzhen , Li Chaowei , Zhu Bin , Chen Yurong , Zhu Ye , Cao Peihai , Dong Zepeng , Feng Luyao , Yu Junhui , Sun Xuejun , Mahmood Zeshaan Yahaya Haji , Bu Yazhong , Du Baoji , Zheng Jianbao 
Published: November 2024

AbstractPostoperative anastomotic leakage (AL) and abdominal adhesions are two major complications after intestinal surgery, with an incidence of 2–25% for AL and 93% for adhesion. Until now, there is no method addressing AL and abdominal adhesions simultaneously. In this work, Bi‐PEG–succinimidyl succinate (PEG‐NHS), amino‐gelatin (Agel) is combined with cefoperazone‐sulbactam (SCF) to prepare a multifunctional bioadhesive (SCF/SEAgel) for the postoperative leakage and adhesion prevention. SCF/SEAgel possesses a great sealing capability for tissue, with a bursting pressure of 54 kPa. The loaded SCF endows the systems with good antibacterial properties. The in vivo antiadhesion experiments show that SCF/SEAgel possesses better anti‐adhesion properties than the commercially used sodium hyaluronate gel. In the cecum leakage model, the SCF/SEAgel effectively seals the leakage with a survival rate of 100%, superior to commercial products (Sainaoning). Meanwhile, it significantly reduces tissue adhesion. Finally, the laparoscopic surgery with dogs shows that the SCF/SEAgel can be injected through minimally invasive surgery, demonstrating its ease of use. Combined with its great biocompatibility, SCF/SEAgel is very promising in intestinal surgery.
Fast Dissolution of Chitin in Amino Acids Based Deep Eutectic Solvents Under the Assistance of Microwave
Authors: Wang Jiake , Qin Chao , Xu Bingxia , Yan Lifeng 
Published: November 2024

AbstractDue to the abundant hydrogen bond networks, high crystallinity, and high molecular weight of chitin, it is difficult to dissolve chitin in most solvents. Meanwhile, most of the existing solvent systems have the disadvantages of high toxicity, low solubility, and high cost. Therefore, the efficient and rapid dissolution of chitin using green solvents is urgently needed. In this work, ternary DES with amino acids, urea, and 1,8‐Diazabicyclo[5.4.0]undec‐7‐ene (DBU) is prepared at first. Then chitin can be dissolved fastly with the assistance of a microwave. Compared with the conventional heating process (110 °C, 6–8 h), the microwave process can be shortened to only 3–10 min. The successful dissolution of chitin is verified by means of fourier transform infrared spectrometer (FT‐IR), X‐ray diffraction (XRD), rheology studies, and optical light microscope, and the dissolution mechanism contributed to the synergistic destroying of the hydrogen bond networks of chitin by amino acids and DBU. The DES solvent can be well recovered with the remaining of its dissolving ability to chitin.
Online Game Supply Chain Coopetition With Product Substitution
Authors: Hu Benyong , Zhang Yanqiu , Chen Xu , Meng Chao 
Published: November 2024

ABSTRACTThis study examines the coopetition decision‐making in an online game supply chain involving two online game development enterprises (the developers) and one online game sales platform (the platform). In supply chain cooperation, competing developers can cooperate with the platform either separately or collectively. In contrast to previous studies, this study not only examines online games, with their unique cost structures, but also innovatively uses product quality as a decision variable in the characterization of product demand. It begins by constructing decision‐making models that reflect three different coopetition situations among enterprises in the online game supply chain: a competition model, a separate bargaining model, and a collective bargaining model. Equilibrium analysis of the decision‐making models is then used to obtain the enterprises' optimal coopetition strategies, and to reveal how these strategies depend on product substitutability and bargaining power. Finally, a comparative analysis of the coopetition models is used to identify the optimal coopetition strategy in the online game supply chain and reveal this strategy's dependence on product substitutability, bargaining power, and internal operating capabilities. These findings provide strategic guidance for enterprises in the online game supply chain about how to pursue coopetition within various business environments.
Preparation of phosphorous ionic liquids and its effect on the properties of ABS
Authors: Zhang Jiayu , Long Jiapeng , Liang Bing 
Published: November 2024

AbstractTo improve the thermal conductivity and mechanical properties of graphene‐acrylonitrile butadiene‐styrene plastic (ABS) composite, sub‐phosphite‐based ionic liquid (IL) was synthesized, and its structure was characterized by FTIR, NMR, and mass spectrometry. IL was as a modifier, and graphite powder (G powder) was modified by the ball milling method to obtain functional graphene thermal conductive filler (G‐IL). The structure and morphology of G‐IL were characterized by FTIR, X‐ray photoelectron spectroscopy (XPS), XRD, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The results of the Molau test showed that the presence of IL improved the interfacial interaction of G‐IL and ABS, enhanced the dispersion of G‐IL in the ABS matrix, made G‐IL contact with each other, and it was easier to establish a thermal conduction network and promote phonon transfer. The thermal conductivity of 9 wt% G‐IL/ABS composite was 0.392 W·m−1·k−1, which was 96% and 14% higher than that of pure ABS and G/ABS composite, respectively. The tensile strength and bending modulus of 9 wt% G‐IL/ABS composite were 44.89 and 2124.37 MPa, which were 13% and 11% higher than those of pure ABS, respectively. The impact strength of 9 wt% G‐IL/ABS composite was 34.17 kJ/m2. It was 18% and 7% higher than that of pure ABS and 9 wt% G‐IL/ABS, respectively.Highlights
Phosphorus imidazole ionic liquids were prepared.
Graphene was modified by ionic liquids through non‐covalent.
Enhanced mechanical properties and thermal conductivity of G‐IL/ABS composites.
Geometric Relational Framework for General‐Relativistic Gauge Field Theories
Authors: François Jordan T. , Ravera Lucrezia 
Published: November 2024

AbstractIt is recalled how relationality arises as the core insight of general‐relativistic gauge field theories from the articulation of the generalized hole and point‐coincidence arguments. Hence, a compelling case for a manifestly relational framework ensues naturally. A formulation for such a framework is proposed, based on a significant development of the dressing field method of symmetry reduction. A version for the group of automorphisms of a principal bundle over a manifold is first developed, as it is the most natural and elegant, and as hosts all the mathematical structures relevant to general‐relativistic gauge field theory. However, as the standard formulation is local, on , the relational framework for local field theory is then developed. The generalized point‐coincidence argument is manifestly implemented, whereby the physical field‐theoretical degrees of freedoms co‐define each other and define, coordinatize, the physical spacetime itself. Applying the framework to General Relativity, relational Einstein equations are obtained, encompassing various notions of “scalar coordinatization” à la Kretschmann–Komar and Brown–Kuchař.
The oviposition of cotton bollworms stimulates the defense against its eggs and larvae in tomato plants
Authors: Shi Jin‐Hua , Shao Rui , Abdelkhalek Sara T , Zhang Shuo , Wang Man‐Qun 
Published: November 2024

AbstractBACKGROUNDHerbivorous insects sustain their populations by oviposition. To reduce the damage caused by herbivores, the host plant triggers a defensive response upon detection of egg deposition. However, the specific impact of the egg deposition time of the cotton bollworm Helicoverpa armigera (Lepidoptera: Noctuidae), on the tomato plant defense remains obscure.RESULTSThis study investigated the effects of tomato plant defenses on cotton bollworm eggs and larvae at different time intervals following egg deposition. The study revealed that tomato plant defense triggered by egg deposition did not directly affect the hatchability of the eggs. Nevertheless, it attracted Trichogramma chilonis 48 h after the egg deposition. Gas chromatography–mass spectrometry analysis of the oviposition‐induced plant volatiles (OIPVs) revealed a considerable increase in the amount of α‐pinene released by tomato plants 48 h after egg deposition. The olfactory results from Y‐tube experiments showed that α‐pinene exhibited a substantial attraction towards T. chilonis. In addition, it was found that the defense response induced by egg deposition for 24 and 48 h significantly inhibited the growth and development of the larvae. Metabolomics analysis revealed that the egg deposition of cotton bollworm altered the metabolite composition and caused significant modifications in the metabolic pathways of tomato plants.CONCLUSIONThese findings provide novel insights into pest management by using egg‐induced plant defenses to reduce egg hatching, and impede larval growth and development in herbivorous insects. © 2024 Society of Chemical Industry.
Time‐Varying Sliding Mode Based Fixed‐Time Missile Guidance and Attitude Control With Impact Angle Constraints
Authors: Wei Shenghui , Song Shenmin 
Published: November 2024

ABSTRACTConsidering an unpowered missile diving to intercept a maneuvering target, a novel fixed‐time guidance and attitude control algorithm is proposed. First, the second‐order derivatives of the aerodynamic angles are directly linked to the fin deflections, which can avoid the tracking of missile body angle rate instruction in the traditional methods. Second, a novel fixed‐time time‐varying parameter nonsingular terminal sliding mode guidance law is proposed, which can avoid control input singularity without switching to the polynomial form when the error approaches the origin. Third, a new global time‐varying sliding mode with a predefined convergence time and analytical solution is developed to design the attitude controller. The system states are proved to be fixed‐time convergence based on the Lyapunov stability theory. Six‐degree‐of‐freedom simulations are conducted to validate the superiority of the proposed algorithm in terms of miss distance, impact angle error, interception time and control energy.
The pathway to sustainable development: The roles of financial development, technological innovation, and educational development in energy poverty alleviation
Authors: Latief Rashid , Javeed Sohail Ahmad , Ashraf Sumaira 
Published: November 2024

AbstractThis paper investigates the dynamics of energy poverty by evaluating the roles played by financial development, technological innovation, and educational development, among other factors. It seeks to identify pathways for sustainable development in the Belt and Road Initiative (BRI) countries. Based on recent panel data from 2000 to 2020, this research classified the sample into various income groups for a comparative analysis. A multidimensional comprehensive index of energy poverty was then formulated through principal component analysis (PCA). This study assesses the relationships between variables using a novel panel quantile autoregressive distributed lag (QARDL), ordinary least squares (OLS), panel unit root tests, Kao cointegration tests, and Wald tests. The results of the Kao tests confirm the presence of cointegration among the variables across all income groups and the overall sample. The panel QARDL approach indicates a significant and negative long‐term relationship between financial development and energy poverty across all income groups other than the low‐income countries. Similarly, technological innovation has a negative long‐term association with energy poverty for most groups, with the exception being the upper‐to‐middle‐income countries. Furthermore, educational development negatively influences energy poverty in the long term for all groups other than lower‐middle‐income countries. The findings for the overall sample suggest that financial and educational development are negatively connected with energy poverty in both the long and short term, while technological innovation only has a negative connection in the short term. In addition, the Wald test results revealed time‐varying integration and parameter stability in both the long and short terms.