bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case of gastric leiomyosarcoma in a domestic shorthair cat
Authors: Hart Kirsty , Brooks Brownlie Harriet , Ogden Daniel , Atencia Sabela 
Published: December 2018

Case summary A 10-year-old male neutered domestic shorthair cat presented with nausea and 1.2 kg weight loss over a 6 month period. Physical examination was unremarkable, and haematological and biochemical results were considered clinically unremarkable. Abdominal ultrasound revealed an 18 mm diameter heterogeneous mass in the stomach at the pyloric sphincter, protruding into the gastric lumen with loss of gastric wall layering. The remainder of the intestinal tract and abdominal viscera were unremarkable and no free fluid was detected. The mass was surgically resected via celiotomy and the adjacent lymph node excised for histopathology. Histopathology of the mass demonstrated neoplastic spindle cell proliferation, which was considered most likely to be of smooth muscle origin, and so a preliminary diagnosis of gastric leiomyosarcoma was given. Complete excision was confirmed. Immunohistochemistry excluded a gastrointestinal stromal cell tumour as a differential and strongly supported the diagnosis of gastric leiomyosarcoma. The cat recovered well postoperatively with supportive treatment. Repeat abdominal ultrasonography 3 and 6 months postoperatively showed no evidence of mass regrowth. Survival time at the time of reporting is 10 months. Relevance and novel information To our knowledge, this is the first report of gastric leiomyosarcoma in a cat. Based on this case, gastric leiomyosarcoma should be a differential diagnosis for cats presenting with a gastric mass.
Comprehension of novel metaphor in young children with Developmental Language Disorder
Authors: Bühler Daniela , Perovic Alexandra , Pouscoulous Nausicaa 
Published: December 2018

Background and aims Difficulties with aspects of morphosyntax, phonology and/or vocabulary are the hallmark of Development Language Disorder (DLD). Yet, little is known about the linguistic-pragmatic abilities of young children with DLD. Previous studies suggest that children with DLD are experiencing difficulties with idioms, sayings and slang expressions, often interpreting them in a literal or unconventional fashion. However, it is unclear whether this is caused by difficulties to make pragmatic inferences in general or whether it stems from their semantic abilities. We therefore investigated novel metaphor understanding in young children with and without DLD. Methods We assessed novel metaphor comprehension using a reference assignment task with 15 children with DLD diagnoses (ages 42–49 months) as well as typically developing peers matched on chronological age (n = 15) and on language (n = 15). Results Children with DLD performed worse than their age-matched peers but in a comparable manner to the (younger) language-matched typically developing children. Performance was not related to non-verbal intelligence in the children with DLD. Conclusion The findings indicate that young children with DLD have difficulties with metaphor comprehension but also suggest that these difficulties are in line with their general language difficulties and linked to their overall linguistic competence rather than reflecting additional specific issues with deriving pragmatic inferences. Implications Our study adds to a growing body of literature showing that children with low language abilities are also likely to display more difficulties in understanding figurative language independently of any other symptomatology of their clinical diagnosis. It also supports the argument that deficits in the pragmatic domain are a secondary impairment rather than a core deficit in children with DLD. Nonetheless, children with DLD do show difficulties in understanding metaphors. Understanding figurative language is necessary for everyday communication and should therefore be targeted alongside traditional treatments by clinicians treating children with DLD.
Acute Exercise Effects among Young Adults with Analogue Generalized Anxiety Disorder
Authors: HERRING MATTHEW P. , MONROE DEREK C. , GORDON BRETT R. , HALLGREN MATS , CAMPBELL MARK J. 
Published: December 2018

ABSTRACT
Recent findings support positive effects of acute aerobic exercise on worry, state anxiety, and feelings of energy and fatigue among young adult women with subclinical, or analogue, generalized anxiety disorder (GAD). However, exercise effects among young adult men with analogue GAD are unstudied.

Purpose
This study replicated initial findings of positive effects of acute vigorous-intensity aerobic exercise on worry, state anxiety, and feelings of energy and fatigue among young adult women with analogue GAD, examined responses among young adult men with analogue GAD, and explored sex-related differences and moderation by physical activity level, trait anxiety, depression, and poor sleep status.

Methods
Thirty-five young adults (21.4 ± 2.3 yr; 19 males; 16 females) with Penn State Worry Questionnaire scores ≥45 (60 ± 8) completed two counterbalanced 30-min conditions: treadmill running at ~71.2% ± 0.04% HR reserve and seated quiet rest. Outcomes included worry, worry engagement, absence of worry, state anxiety, and feelings of energy and fatigue.

Results
No outcome or moderator differed at baseline between sexes. Exercise significantly improved state anxiety (P < 0.04; d = 0.27) and feelings of energy (P < 0.001; d = 1.09). Small nonsignificant improvements were found for worry (d = 0.22), worry engagement (d = 0.18), and feelings of fatigue (d = 0.21). The magnitude of improvements in worry, worry engagement, absence of worry, and feelings of energy were stronger among females. Significant large, potentially clinically meaningful increases in feelings of energy were found among women (d = 1.35) and men (d = 0.92). A nonsignificant, but potentially clinically meaningful, moderate reduction in worry (d = 0.53) was found among women. High-trait anxiety and poor sleep quality were supported as moderators.

Conclusions
Findings replicated positive effects of acute aerobic exercise among young adult women with analogue GAD, and extended to support for positive effects among young adult men with analogue GAD.
The challenges of designing a benchmark strategy for bioinformatics pipelines in the identification of antimicrobial resistance determinants using next generation sequencing technologies
Authors: Angers-Loustau Alexandre , Petrillo Mauro , Bengtsson-Palme Johan , Berendonk Thomas , Blais Burton , Chan Kok-Gan , Coque Teresa M. , Hammer Paul , Heß Stefanie , Kagkli Dafni M. , Krumbiegel Carsten , Lanza Val F. , Madec Jean-Yves , Naas Thierry , O'Grady Justin , Paracchini Valentina , Rossen John W.A. , Ruppé Etienne , Vamathevan Jessica , Venturi Vittorio , Van den Eede Guy 
Published: December 2018

Next-Generation Sequencing (NGS) technologies are expected to play a crucial role in the surveillance of infectious diseases, with their unprecedented capabilities for the characterisation of genetic information underlying the virulence and antimicrobial resistance (AMR) properties of microorganisms. In the implementation of any novel technology for regulatory purposes, important considerations such as harmonisation, validation and quality assurance need to be addressed. NGS technologies pose unique challenges in these regards, in part due to their reliance on bioinformatics for the processing and proper interpretation of the data produced. Well-designed benchmark resources are thus needed to evaluate, validate and ensure continued quality control over the bioinformatics component of the process. This concept was explored as part of a workshop on "Next-generation sequencing technologies and antimicrobial resistance" held October 4-5 2017. Challenges involved in the development of such a benchmark resource, with a specific focus on identifying the molecular determinants of AMR, were identified. For each of the challenges, sets of unsolved questions that will need to be tackled for them to be properly addressed were compiled. These take into consideration the requirement for monitoring of AMR bacteria in humans, animals, food and the environment, which is aligned with the principles of a “One Health” approach.
Pre-treatment loss to follow-up among patients with rifampicin-resistant tuberculosis in Baluchistan, Pakistan, 2012-17: a retrospective cohort study
Authors: Kurd Shoaib Aziz , Wali Ahmed , Fatima Razia , Yaqoob Aashifa , Khan Dawood , Lehri Sultan 
Published: December 2018

Background: Patients with rifampicin-resistant TB (RR-TB) pretreatment loss to follow-up continue to be a global health challenge. Although the accuracy of diagnosis significantly increased with the implementation of Xpert MTB/RIF assay, which is a rapid molecular based test and more sensitive than conventional microscopy which detects MTB even present in small limit of 136 MTB/ml of sputum, but still data suggest a wide treatment initiation gap among diagnosed. This study was done to assess the proportion of patients with RR-TB pretreatment lost to follow-up and the socio-demographic factors associated with this in Balochistan, Pakistan. Methods: This was a retrospective cohort study based on review of the routinely managed program records. The data included all patients with RR-TB detected at Fatima Jinnah Chest & General Hospital Quetta and District Head Quarter Hospital Loralai, Xpert sites and enrolled at programmatic management of drug resistant TB (PMDT) sites during 2012-2017. Data collected was double-entered, validated and analyzed using EpiData. Results: Of the 396 patients with RR-TB detected during 2012-17, 78 (19.8%) underwent pre-treatment lost to follow-up. The mean age of those detected with RR-TB was 37 years (SD ±16.98); 189 (48%) were of age group 15-34, while 60% were female. Among 84 individuals referred out to other facilities, only 6 started treatment. Almost half of the ‘pretreatment lost to follow-up’ patients were from age group 15-34, while 43 were from within the Quetta and Loralai districts. Conclusions: The high proportion of patients with RR-TB that were pre-treatment lost to follow-up in Balochistan needs immediate strategies to establish linkages between Xpert and PMDT sites for the timely management of patients to prevent the spread of RR-TB infection.
Medieval Reports of the Preservation and Looting of Pre-Islamic Burials in South Arabia
Authors: Mahoney Daniel 
Published: December 2018

Abstract
In the tenth century, the polymath Abu Muhammad al-Hamdani compiled a ten-volume compendium, entitled al-Iklı-l (The Crown), which narrates the history of South Arabia from the pre-Islamic to the early Islamic periods with the aim of extolling the various achievements and virtues of this region. The eighth volume of this compendium contains a collection of reports that describe the uncovering of pre-Islamic burials in the early Islamic period. Although the veracity of some reports may be questioned due to their inclusion of fantastical elements, these accounts portray a vivid imagining of the ancient tombs themselves and the stories of those buried within, as well as show the varied reactions to these sites. In some reports, the interred are revered and the chambers are returned to their former state. But in others, ambivalence is shown toward those buried, even when the inscriptions found at the site communicate that the interred testified to a belief in one god, and the tombs are looted. Overall, these rich reports do not merely depict encounters with pre-Islamic funerary remains, but also serve to connect South Arabia’s past with major narratives and themes of Islamic history.
Kandungan Logam Berat Timbal (Pb) Pada Air, Sedimen, Dan Rumput Laut Sargassum sp. Di Perairan Teluk Awur, Jepara
Authors: Malau Rotua , Azizah Ria , Susanto AB , Santosa Gunawan Widi , Irwani Irwani 
Published: December 2018

Concentration of the Heavy Metal Lead (Pb) in the Seawater, Sediment, and the Seaweed Sargassum sp. in Teluk Awur, Jepara The increasing human activities led to an increase in waste disposal which eventually accumulates and decrease the water quality of rivers and seas. One of the pollutant resulted by human activities is heavy metal. The presence of heavy metals in the waters could directly harm the bioorganisms and indirectly affect human health by food chains. The purpose of this research is to investigate the lead content (Pb) in the water, sediment, and seaweed Sargassum sp., as well as to determine the status of pollution in Teluk Awur waters, Jepara. The research was conducted in November 2017 and January 2018 using descriptive method. Sampling sites were decided by Purposive Sampling Method. Analysis of lead content was conducted using AAS (Atomic Absorption Spectrophotometry). The results showed that the lead content of seawater in Teluk Awur, Jepara, was within 0.003 mg/L and not on the level of concern, according to KepMen LH No. 51/2004. The range of lead content in the sediment was 47- 68,35 mg/kg and considered as polluted, according to NRCC GBW07313. The range of lead content in the seaweed Sargassum sp. was 0.22-0.79 mg/kg and has exceeded the quality standard specified by PerBPOM No. 23/2017. Meningkatnya kegiatan manusia menyebabkan peningkatan pembuangan limbah yang pada akhirnya bermuara ke sungai maupun laut, yang mengakibatkan perairan laut menjadi tercemar. Salah satu pencemar akibat aktivitas manusia adalah logam berat timbal yang dapat membahayakan kehidupan organisme perairan secara langsung, maupun tidak langsung terhadap kesehatan manusia. Tujuan penelitian ini adalah untuk mengetahui kandungan logam berat Pb pada air, sedimen, dan rumput laut Sargassum sp. serta untuk mengetahui status pencemaran di Perairan Teluk Awur, Jepara. Penelitian dilakukan pada bulan November 2017 dan Januari 2018. Metode penelitian yang digunakan adalah metode deskriptif. Penentuan lokasi penelitian dilakukan dengan Purposive Sampling Method. Analisis logam berat Pb dilakukan dengan menggunakan AAS (Atomic Absorption Spectrophotometry). Hasil penelitian menunjukan kandungan logam berat Pb di Perairan Teluk Awur, Jepara, pada air laut yaitu 0,003 mg/L dan masih belum tercemar menurut KepMen LH No.51/2004. Kandungan logam berat Pb pada sedimen yaitu berkisar 47 - 68,35 mg/kg dan telah tercemar menurut NRCC GBW07313. Kandungan logam berat Pb pada rumput laut Sargassum sp. yaitu berkisar 0,22 - 0,79 mg/kg dan telah melebihi baku mutu yang ditentukan oleh PerBPOM No. 23 Tahun 2017
A Preliminary Study on the Newly Isolated High Laccase-producing Fungi: Screening, Strain Characteristics and Induction of Laccase Production
Authors: Wang Qian , Qian Yingying , Ma Yuhan , Zhu Changwei 
Published: December 2018

AbstractA simple separation method was used in this study to directly separate laccase-producing fungi from withered plant materials. A laccase-producing filamentous fungus was isolated and purified. The strain was highly similar to the species in genus Trametes by ITS sequence analysis, and therefore named Trametes sp. MA-X01. The addition of cupric ions and aromatic compounds to the liquid medium could induce the laccase synthesis in Trametes sp. MA-X01. Copper-induced laccase activity increased in a dose-dependent manner. The highest laccase activity (2138.9 ± 340.2 U/L) was obtained by adding 2.5 mM Cu2+ to the culture medium, which was about 7 times higher than that of the control group. The induction degree of aromatic compounds was different. For the present study, the highest laccase activities were obtained by adding vanillic acid (1007.9±59.5 U/L) or vanillin (981.6±77.2 U/L) to the medium, which were 3.5 and 3.4 times higher than the laccase activity of the control group, respectively.
Mut und Partizipation
Authors: Röbel Marc 
Published: December 2018

Abstract
With his analysis of courage as a foundational theme of modern existential philosophy, Tillich answers, in “The Courage to Be“: dread, which is a key motif in the thought of Kierkegaard, Heidegger, and Sartre, and which also gains importance in ‘existential America’ at the same time. This essay documents the innovative existential philosophical character of the work under the guidance of the concept of ‘participation.’ The book is much more than a theological bestseller. It is also evidence of the wealth of perspectives of existential thought that reveals insightful ethical and political perspectives beyond the religious and philosophical aspects typical of Tillich.
Decapod crustaceans in benthic habitats of the Turkish Straits System with new records
Authors: Bakir Ahmet Kerem , Ateş A. Suat 
Published: December 2018

AbstractThe objective of this study was to investigate decapod species occurring in the Turkish Straits System. For this purpose, benthic samples were collected from six different biotopes (photophilic algae,Cystoseira barbata, meadows,Posidonia oceanica, mussel,Mytilus galloprovincialis, meadows,Zostera marina, serpulid reef, and rocks) at depths ranging from 10 to 1000 m. A total of 60 species of decapod crustaceans were identified, including new records for the Turkish Straits System:Processa elegantula,P. modica,Richardina fredericii,Callianassa subterranea,Gourretia denticulata,Inachus parvirostrisandMacropodia linaresi. In addition, some information about the spatial and bathymetric distribution as well as biotope preferences of the decapod community is provided.
Kasuale Lehrgedichte im Kontext der aufklärerischen Gelehrtenrepublik
Authors: Krämer Olav 
Published: December 2018

Abstract
In the early decades of the eighteenth century, a number of German authors published poems that combined features of occasional and didactic poetry. The article examines ›occasional-didactic poems‹ by Johann Christoph Gottsched and Abraham Gotthelf Kastner that were read out loud at academic ceremonies. The study seeks to show that Gottsched and Kastner used this hybrid genre to intervene in, or to comment on, quarrels and controversies within the learned world, in particular controversies involving different faculties and disciplines. Thus, these poems should not be dismissed as mere attempts to upgrade the much-criticized genre of occasional poetry by adding philosophical digressions. Rather, they constitute one of the specific forms of communication developed within the Enlightenment republic of letters. In addition, these poems are instructive with respect to the development of eighteenth-century didactic poetry in general.
(Im)politeness in the Iliad: The Pragmatics of the Homeric Expression ἀγαθός περ ἐών
Authors: Lentini Giuseppe 
Published: December 2018

Abstract
Every communication has a relationship aspect in addition to a content aspect: this axiom of Watzlawick’s Pragmatics of Human Communication proves useful also when studying the dialogues contained in literary works. The ἀγαθός περ ἐών formula occurring five times in Homer’s Iliad has appeared difficult to interpret precisely because scholars have failed to take into account the relationship aspect of the verbal interactions described. Employed as a conventional politeness formula manifesting respect for the hearer, the ἀγαθός περ ἐών expression could also be used in contexts that clash with a ‘polite’ interpretation, thus generating mock-politeness and, ultimately, ‘impoliteness’.
Removing the Nationality Paradigm from Herodotus’ Histories
Authors: Tufano Salvatore 
Published: December 2018

Abstract
The present paper suggests that the recurring appeal to kinship diplomacy undermines a fixed idea of ‘nation’ in Archaic Greece, especially in the first two decades of the fifth century BC. It aims to present a series of test cases in Herodotus that explain why contemporary patterns and theories on ancient ethnicity can hardly explain the totality of the historical spectrum. Blood ties could sometimes fortify ethnic relationships, as in the case of Aristagoras’ mission to Sparta (Hdt. 5.49.3), since the common Greekness could elicit the Spartan to help to the Ionians. In other times, the same blood ties were applied to divine genealogies, and they could also be used to show the feeble devotion of cities like Argos to the Greek cause (7.150.2: Xerxes expects the Argives to join the Persian cause, since they descend from Perses). Habits and traditions, often taken as indicia of national feeling, could be thought of as clues of ancient migrations (so the Trojans became Maxyes in Lybia: 4.191). Even language might not help in justifying ethnic relationships: for instance, the Greeks living in the Scythian Gelonus spoke a mixed language (4.108). These few case studies may shed a different light on the classical definition of Greekness (to hellenikon) in terms of blood, language, cults, and habits, all given by Herodotus (8.144). Far from being a valid label for all the Greeks of the fifth century, this statement owes much to a specific variety of the language of kinship diplomacy. The final section argues for the opportunity to avoid the later and misleading idea of nation when studying Herodotus and the age of the Persian Wars, which are instead characterized by various and contrasting strategies. Greek groups and ethne can be better described as networks of lightly defined communities.
Pinceladas do sertão: formação, experiência e abertura educomunicacional no semiárido baiano
Authors: Araújo Henrique Oliveira de , Amar Victor 
Published: December 2018

Para além dos conteúdos fetichizados da mídia de massas, o presente artigo leva em consideração as expressões, sentimentos e subjetividades daqueles que Touraine e Khosrokhavar (2002) chamaram de “indivíduos em subjetivação” no contexto do Semiárido baiano. Em outras palavras, o texto que se segue defende uma comunicação que educa através de uma práxis e de um conhecimento mestiçado: misturado pela transversalidade cultural e experiencial dos sujeitos e que se lança ao desafio de refletir sobre outra possibilidade formativa. Palavras-chave: Educação, Comunicação, Formação, SubjetividadeBrushes of the sertão: training, experience and educommunicational opening in Bahia´s semi-aridAbstract In addition to the fetishized contents of the mass media, this article takes into account the expressions, feelings and subjectivities of those that Touraine and Khosrokhavar (2002) called "individuals in subjectivation" in the context of Bahia semi-arid. In other words, the following text defends a communication that educates through a praxis and a mestizo knowledge: mixed by the cultural and experiential transversality of the subjects, and that launches the challenge of reflecting on another formative possibility.Keywords: Education, Communication, Formation, SubjectivityPinceladas del sertão: educación, experiencia y apertura educomunicacional en semiárido baianoResumen Además del contenido fetichista de los medios de comunicación, este artículo tiene en cuenta las expresiones, sentimientos y subjetividades de quienes Touraine y Khosrokhavar (2002) llaman de "individuos en subjetivación" en el contexto del semiárido Bahiano. En otras palabras, el texto que sigue sostiene una comunicación que educa a través de una práctica y un conocimiento mestizo: mezclado por la transversalidad cultural y vivencial de los sujetos, y que se pone en el reto de reflexionar sobre una otra posibilidad formativa.Palabras-clave: Educación, Comunicación, Formación, Subjetividad