bluuebunny/crossref_metadata_2025_split huggingface dataset:
hubungan sumber informasi, dukungan suami dan tingkat keceamsan terhadap keikutsertaan akseptor kb iud di pmb r. didesa kubang baros kec. cinangka kab. serang -banten tahun 2022
Authors: Ajjah Ratna 
Published: December 2024

Banyak Faktor yang mempengaruhi pemilihan alat kontrasepsi IUD antara lain adalah sumber informasi, Kegiatan penyuluhan keluarga berencana dimaksudkan untuk lebih meningkatkan kesadaran, pengetahuan, sikap dan praktek masyarakat dalam berkeluarga berencana menuju terwujudnya keluarga kecil bahagia dan sejahtera. Tujuan penelitian ini untuk mengetahui Hubungan Sumber Informasi, Dukungan Suami Dan Tingkat Kecemasan Terhadap Keikutsertaan Akseptor KB Iud di PMB R. di Desa Kubang Baros Kec. Cinangka Kab. Serang – Banten Tahun 2022. Penelitian ini menggunakan desain desain deskriptif analitik menggunakan metode kuantitatif dengan pendekatan desain penelitian Cross Sectional. Jumlah sampel pada penelitian ini sebanyak 36 responden. Hasil penelitianGambaran sumber informasi lebih dari setengahnya sumber informasi dari Online sebanyak 20 (44.4%), Suami tidak mendukung sebanyak 19 (52.8%), merasa cemas sebanyak 24 (66.7%) dan keikutsertaan KB IUD Tidak ikut sebanyak 23 (63.9%) di PMB R. di Desa Kubang Baros Kec. Cinangka kab. Serang - Banten Tahun 2022. Dan kesimpulan penelitian ini adalah terdapat hubungan Sumber Informasi terhadap Keikutsertaan Akseptor KB IUD dangan (p= 0,005 p < a atau 0,005 < 0.05). Terdapat hubungan dukungan suami terhadap Keikutsertaan Akseptor KB IUD dengan (p= 0,014 p < a atau 0,014 < 0.05). Terdapat hubungan tingkat kecemasan terhadap Keikutsertaan Akseptor KB IUD dengan (p = 0,010 p < a atau 0,010 < 0.05). PMB R dapat meningkatkan pemahaman kepada akseptor KB tentang penggunaan KB IUD Baik melalui pelatihan pemasangan AKDR maupun melalui seminar-seminar tentang AKDR

Kata kunci : Dukungan Suami, Sumber Informasi, Tingkat Kecemasan
მონოლოგური და დიალოგური დისკურსი და მიმართვის ფორმები პიერ კორნელის „ჰორაციუსის“, „ცინას“ და „პომპეუსის სიკვდილის“ მიხედვით
Authors: ანთია თამარ 
Published: December 2024

In Pierre Corneille's "Roman Tragedies"-“Horace”, “Cinna” and “The Death of Pompey” the types of dramatic discourse – dialo­gues and mono­logues – occupy an important place. Dialogues and monologues have the function of self-expression of the characters.
Monologue is one of the best ways to illustrate the characters' thoughts and inner feelings. According to the poetics of classicism, when the character is alone on stage, the principle of persuasiveness requires that he express his thoughts, which he often expresses in the form of a dialogue with himself, which he or she does not want anyone to hear.
Through the monologue of the characters of Corneille's tragedies they not only carefully examine the hidden sides of their souls and convince themselves of the necessity of certain actions, but also examine and review possible decisions and the advantages and disadvantages of these decisions.
In “Horace”, “Cinna” and “The Death of Pompey” the mono­lo­gue has the following functions:

Through monologue, the actors of the tragedy express their personal feelings and attitudes.
Through monologue, the characters of the tragedy judge and analyze this or that idea and point of view.

Dialogue, like monologue, is a basic and important form of dramatic speech. P. Cornielle perfectly uses dialogues in "Roman tra­gedies" for the purpose of exchange of ideas between actors, tho­rough reasoning about the problem and persuasion of the interlocutor.

Corneille's emotionally charged dialogues with a high tragic register express the pathos and ethos of the actors, their thoughts and inner feelings.

In “Horace”, “Cinna” and “The Death of Pompey” Pierre Cor­neille, in addition to monologue and dialogic discourse, uses such rhetorical-stylistic means as: formal ("you") and informal ("you") forms of address and apos­trophes – "Seigneur", "Madame", "Princess", "Prince", "reine" and others. The use of the formal – "you" form of address is related to the rule accepted in the aristocratic society of France during the Pierre Corneille era, according to which the aristocracy mainly used the formal "you" of address in the 17th cen­tury. Pierre Corneille created tragedies, first of all, for the king and the society of the royal court, and the vocabulary of the acting heroes of the tragedy should be high and pathetic.
As for the „you“ informal of address, its use by the characters indicates their emotional change, and the use of apostrophes orga­nizes the inter­locutive space in which the speakers, using evidence, in a state of emotional rapture or affect, directly convey what they have to say.
EFEITOS DO LEITE COM A PROTEÍNA Β-CASEÍNA A1 X A2 PARA A SAÚDE HUMANA: REVISÃO DE LITERATURA
Authors: Correia Rute Santos 
Published: December 2024

O leite bovino é mais consumido no mundo e no Brasil, sendo reconhecido por ser um alimento de alto valor nutricional devido sua composição apresentar diversos nutrientes. Dentre as proteínas presentes, as caseínas constituem um grupo de maior predominância, com destaque para a β-caseína, mais amplamente estudada e difundida as suas variantes A1 e A2, principalmente devido as suas diferenças estruturais e os diversos efeitos na saúde humana. Historicamente, a β-caseína A2 é reconhecida como a variante original, enquanto a A1 surgiu a partir de uma mutação genética transversal na posição do aminoácido 67. Como consequência dessa modificação estrutural o consumo de leite que apresenta a β-caseína A1 tem influenciado na sua digestão, com a liberação do peptídeo beta-casomorfina-7, que apresenta propriedades semelhantes a opioides podendo provocar diversas desordens no organismo humano, como distúrbios gastrointestinais, doenças metabólicas, cardiovasculares e distúrbios no sistema nervoso. Diversos estudos são realizados para elucidar as comparações entre as duas variantes que têm impactado diretamente a população consumidora, tendo em vista, que a β-caseína A2 tem se mostrado benéfica a saúde devido a semelhança físico-química com o leite materno.
Factores que afectan el desarrollo del sector de molinería de arroz en el departamento norte de santander
Authors: Sierra Narváez Francisco Javier , Bohórquez Mantilla Gustavo Enrique , Contreras Manuel Antonio 
Published: December 2024

El objetivo de la investigación fue realizar un diagnóstico para identificar los factores que condicionan el desarrollo del sector molinería de arroz en el Departamento Norte de Santander. Se ejecutó un estudio descriptivo apoyado en un diseño de campo. Se evaluaron los factores de competitividad utilizando el Modelo de las cinco fuerzas de Porter, además se realizó el análisis interno y externo para identificar los elementos que están impactando la capacidad del sector para su desarrollo. Los resultados obtenidos permitieron identificar algunas falencias y también potencialidades para las empresas del sector arrocero en el Departamento Norte de Santander. Todo el conjunto de factores de competitividad evidencia que el mercado de este sector arrocero exige condiciones de eficiencia y efectividad de las empresas participantes para lograr adecuados niveles de competitividad. El análisis interno permitió identificar fortalezas en cuanto a capacidad financiera, capacidad de producción y de comercialización, aunque presenta deficiencias en la gestión del talento humano. Respecto al análisis externo, se observaron importantes amenazas derivadas de la evolución del mercado de proveedores; en cuanto a los clientes se observa una oportunidad derivada de la demanda creciente, aunque la escasa reacción del mercado ante la diferenciación del producto puede facilitar la entrada de nuevos competidores que ofrecen mejores precios. Finalmente se determinó que el gobierno está generando condiciones y restricciones legales que pueden afectar la competitividad del mercado. Estos resultados permiten establecer una base para la formulación de acciones, el desarrollo del sector debe estar sustentado en un programa de acción que atienda las deficiencias encontradas y aproveche las ventajas competitivas de este importante sector de la economía colombiana.
Lilin Aromaterapi Dari Ekstrak Bunga Kenanga (Cananga odorata)
Authors: Gama Sabaniah Indjar , Rusli Rolan , Basir Nindya Yolanda 
Published: December 2024

Lilin aromaterapi adalah salah satu bentuk diversifikasi dari prodak lilin, berbeda dengan lilin biasa yang dijadikan sebagai penerangan, perbedaan tersebut terdapat pada penambahan beberapa minyak esensial kedalam basis/formula dari pembuatan lilin, dalam hal ini adalah penambahan minyak atsiri dari bunga kenanga. Bunga kenanga merupakan salah satu tanaman yang mengandung minyak atsiri yakni linalool dan geraniol dari golongan monoterpenoid alcohol yang memiliki khasiat atau aktifitas sebagai relaksasi, menghasilkan efek analgesic, hipotensi, stimulasi, vasoliditasi, dan penyeimbang. Tujuan dari penelitian ini adalah memformulasikan ekstrak bunga kenanga dengan empat konsentrasi 1%, 2%, 3%, dan 4% kedalam bentuk sediaan lilin. Hasil yang diperoleh dari Optimasi sediaan lilin diperoleh Formula 4 memenuhi persyaratan organoleptis tidak patah, padat tidak retak, putih merata dan sedikit cekung , uji titik leleh 55 menit dan uji waktu bakar 116 Menit, sedangkan pengaruh konsentrasi terhadap sediaan lilin untuk F1 dengan konsentrasi minyak atsiri bunga kenanga 1% menunjukan titik leleh tertinggi adalah 57.33 Menit, sedangkan F4 dengan konsentrasi minyak atsiri bunga kenanga 4 % menunjukan titik leleh rendah adalah 54.33 Menit, untuk uji lama waktu bakar 129 Menit terdapat pada formula F3 dengan konsentarsi minya atsiri bunga kenanga 3%, dan waktu uji bakar tercepat pada formula F4 dan F1 adalah 116 dan 106 Menit.
Analyse réflexive de l’émergence du projet « Dialogue sur la Discrimination »
Authors: Arseneault Maude 
Published: December 2024

La force des événements tragiques ayant mené à la mort de George Floyd lors d’une intervention policière filmée en direct, où ses dernières paroles « I can’t breathe » sont devenues un symbole puissant de la violence policière et du racisme systémique, a permis aux mouvements antiracistes de mobiliser une nouvelle génération d’acteurs et d’actrices ainsi que d’outils. Plusieurs pans de la société se sont ainsi retrouvés devant la nécessité de faire de véritables remises en question par rapport au racisme, à la discrimination systémique et à d’autres expressions d’injustice sociale. De mon côté et au sein de mon équipe du LABRRI ont ainsi émergé des questions de fond sur la pertinence et le bon fondement de notre approche interculturelle pour répondre aux enjeux de la discrimination. S’est alors enclenché, au niveau personnel, mais aussi de l’équipe, un « changement d’état d’esprit » qui a fait ressortir différents malaises partagés par certains membres du laboratoire concernant l’antiracisme. Ainsi s’entamait une deuxième phase de réflexions, au sein du laboratoire, sur les courants pluralistes. Cette fois, la réflexion se penchait plus spécifiquement sur les liens entre l’interculturel et l’antiracisme, ce qui a été le point d’émergence du projet de recherche « Dialogue sur la Discrimination » (2D). Cet essai a pour but de retracer ce changement d’état d’esprit et de faire l’analyse réflexive de l’émergence d’un projet mené au sein d’une équipe partenariale de recherche, le projet 2D, mais surtout de poser une réflexion sur sa signification pour l’interculturel au Québec et ailleurs dans le monde.
The influence of Chinese culture and images on the work of 19th-century Russian artists who were part of the Russian Ecclesiastical Mission in Beijing
Authors: Yang Jianqu 
Published: December 2024

The object of the study is the Russian fine art of the XIX century. The subject of the research is the history of the interaction of Russian artists with Chinese culture, history and art, their perception and interpretation, as well as the features of the artistic embodiment of images and motifs. Iconographic, as well as stylistic and compositional analysis help to identify the content of the artists' works, their language and individual techniques. Comparing the works created both during their stay in China and after the completion of the mission allows us to show how Russian authors developed their impressions, contributing to the creation of a certain image of China in the eyes of Russians. The research methodology is based on a combination of techniques aimed at studying various aspects of the phenomenon of representation of Chinese art and culture in Russia. The methodology is based on a comprehensive study and comparison of various types of sources, research of artistic material, namely: works by Russian artists who participated in the activities of the mission, reflecting images and motives, techniques in their work. The interaction of Chinese and Russian art is an urgent topic of research in the art history of both countries. Against the background of the appeal to the assessment of the current situation and the history of such contacts, it is necessary to analyze the processes that influenced their formation. Russian Russian Orthodox Mission in the XIX century. The main, and sometimes almost the only means of maintaining communication between the two states was the activity of the Russian Orthodox Mission, which included painters associated with the Imperial Academy of Arts and, thus, the best traditions of the Russian art school. The stay of Russian artists in China left a certain imprint on their own creative manner, the choice of subjects, the specifics of the composition and the symbols used in conditions of maintaining adherence to academicism and realism.
Beyond Silicon
MOS
: An Electrical Study on Interface and Gate Dielectrics with
ac
Admittance Techniques
Authors: Lin Dennis H.C. , Vais Abhitosh , Gaur Abhinav , Brammertz Guy , Alian AliReza , Nyns Laura , Sioncke Sonja , Delabie Annelies , Asselberghs Inge , Radu Iuliana , Collaert Nadine , De Meyer Kristin , Heyns Marc 
Published: May 2019

Abstract

Recent developments in complimentary metal–oxide semiconductor (CMOS)‐driven compound semiconductors (III–V), Germanium (Ge) and two‐dimensional (2‐D) materials technologies provide new opportunities in advancing the performance envelope of MOS device as well as the relevant electrical characterization techniques. Understanding the electrical characteristics of the metal–oxide–semiconductor (MOS) interface and defects through capacitance‐voltage (CV), conductance voltage (GV) and ac‐transconductance responses can lead to more realistic assessments of the oxide–semiconductor material systems and accurate performance predictions. In this article, interface trap density distributions
D
it
(
E
) of Germanium, III–V compound semiconductors are characterized and/or illustrated. The characterization, modeling and temperature dependence of oxide border traps are presented as the defect study probes beyond the oxide–semiconductor interface. Finally, an investigation on 2‐D materials based MOS devices extends the ac admittance techniques beyond conventional semiconductor materials.
The combination of NPM1, DNMT3A, and IDH1/2 mutations leads to inferior overall survival in AML
Authors: Dunlap Jennifer B. , Leonard Jessica , Rosenberg Mara , Cook Rachel , Press Richard , Fan Guang , Raess Philipp W. , Druker Brian J. , Traer Elie 
Published: May 2019

AbstractAcute myeloid leukemia (AML) is a genetically heterogeneous disease with a clinical course predicted by recurrent cytogenetic abnormalities and/or gene mutations. The NPM1 insertion mutations define the largest distinct genetic subset, ∼30% of AML, and is considered a favorable risk marker if there is no (or low allelic ratio) FLT3 internal tandem duplication (FLT3 ITD) mutation. However, ∼40% of patients with mutated NPM1 without FLT3 ITD still relapse, and the factors that drive relapse are still not fully understood. We used a next‐generation sequencing panel to examine mutations at diagnosis; clearance of mutations after therapy, and gain/loss of mutations at relapse to prioritize mutations that contribute to relapse. Triple mutation of NPM1, DNMT3A and IDH1/2 showed a trend towards inferior overall survival in our discovery dataset, and was significantly associated with reduced OS in a large independent validation cohort. Analysis of relative variant allele frequencies suggests that early mutation and expansion of DNMT3A and IDH1/2 prior to acquisition of NPM1 mutation leads to increased risk of relapse. This subset of patients may benefit from allogeneic stem cell transplant or clinical trials with IDH inhibitors.
Paternal heritage in Jujuy province (Northwest Argentina): Evidence for sex‐biased gene flow and genetic drift effects
Authors: Alfonso‐Sánchez Miguel A. , Gómez‐Pérez Luis , Dipierri José E. , Peña José A. 
Published: May 2019

AbstractObjectivesThis study aimed to explore the diversity of paternal lineages in Jujuy province (Argentina) by analyzing Y chromosome markers. Furthermore, we examined among‐population genetic variability based both on paternally (NRY haplotypes) and maternally (mtDNA haplogroups) inherited markers. We sought to evaluate the impact of sex‐biased gene flow on genetic background in Jujuy, and contribute data on the microevolutionary forces acting in this zone.MethodsDNA from 149 males from five Jujuy regions were analyzed for 12 non‐recombining Y (NRY) markers. Genetic heterogeneity among Jujuy regions was evaluated through population differentiation tests. To identify potential genetic boundaries in Jujuy, analysis of molecular variance (AMOVA) and the Monmonier's algorithm implemented in the Barrier v2.2 software were employed.ResultsA clear divergence between Jujuy highlands and lowlands for NRY haplotypes was found. A marked discrepancy between genetic structuring for paternal lineages and the lack of geographical pattern for mitogenomes was confirmed by all statistical analyses.ConclusionsGenetic structuring of paternal lineages is most likely caused by admixture processes that have occurred since colonial times in the Jujuy lowlands. Immigrants were predominantly male that settled in the lower altitude zones, due to the steep orography of the region. Input of allochthonous male lineages because of gene flow toward the lowlands would have increased diversity of NRY markers, thus compensating for drift effects. Likewise, limited input of allochthonous mitogenomes would have promoted genetic drift, a key factor in the shaping of diversity of maternal lineages across Jujuy subpopulations, irrespective of altitude.
A heterozygous, intragenic deletion of CNOT2 recapitulates the phenotype of 12q15 deletion syndrome
Authors: Alesi Viola , Loddo Sara , Calì Federica , Orlando Valeria , Genovese Silvia , Ferretti Daniele , Calacci Chiara , Calvieri Giusy , Falasca Roberto , Ulgheri Lucia , Drago Fabrizio , Dallapiccola Bruno , Baban Anwar , Novelli Antonio 
Published: May 2019

AbstractOnly a few individuals with 12q15 deletion have been described, presenting with a disorder characterized by learning disability, developmental delay, nasal speech, and hypothyroidism. The smallest region of overlap for this syndrome was included in a genomic segment spanning CNOT2, KCNMB4, and PTPRB genes. We report on an additional patient harboring a 12q15 microdeletion encompassing only part of CNOT2 gene, presenting with a spectrum of clinical features overlapping the 12q15 deletion syndrome phenotype. We propose CNOT2 as the phenocritical gene for 12q15 deletion syndrome and its haploinsufficiency being associated with an autosomal dominant disorder, presenting with developmental delay, hypotonia, feeding problems, learning difficulties, nasal speech, skeletal anomalies, and facial dysmorphisms.
The diagnostic and prognostic value of red cell distribution width in cardiovascular disease; current status and prospective
Authors: Parizadeh Seyed M. , Jafarzadeh‐Esfehani Reza , Bahreyni Amirhossein , Ghandehari Maryam , Shafiee Mojtaba , Rahmani Farzad , Parizadeh Mohammar R. , Seifi Sima , Ghayour‐Mobarhan Majid , Ferns Gordon A. , Avan Amir , Hassanian Seyed M. 
Published: May 2019

AbstractThe red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have shown that an increased in the RDW may be associated with other diseases including acute pancreatitis, chronic kidney disease, gastrointestinal disorders, cancer, and of special interest in this review, cardiovascular disease (CVD). The diagnostic and prognostic value of RDW in different CVD (acute coronary syndrome, ischemic cerebrovascular disease, peripheral artery disease, atrial fibrillation, heart failure, and acute ischemic stroke) has been reviewed in this article, to provide an understanding how its measurement may be applied to improve the management of these conditions.
Pharmacokinetic and tissue distribution studies of cassane diterpenoids, in rats through an ultra‐high‐performance liquid chromatography–Q exactive hybrid quadrupole–Orbitrap high‐resolution accurate mass spectrometry
Authors: Wang Miao , Wang Da , Gao Changjiu , Li Xianzhe , Sha Luping , Zhao Qiang , Gao Huiyuan , Wu Zhaohua 
Published: May 2019

AbstractCassane diterpenoids (CA) are considered as the main active constituents of medicinal plants belonging to the Caesalpinia genus. Three cassane derivatives, bonducellpin G (BG), 7‐O‐acetyl‐bonducellpin C (7‐O‐AC) and caesalmin E (CE), isolated from Caesalpinia minax Hance seeds, showed strong anti‐inflammatory activity. In this paper, pharmacokinetics (BG, 7‐O‐AC, CE) and tissue distribution (7‐O‐AC, CE) properties were studied for the first time using a reliable, sensitive and rapid UHPLC–Q‐Orbitrap HR‐MS to develop new anti‐inflammatory agents. A novel quantitative method with full scan in positive ion mode was used to determine the contents of compounds. They were separated using acetonitrile–water (0.1% formic acid) as gradient mobile phase. The calibration curve displayed good linearity and the lower limit of quantitation was 0.005–0.02 μg/mL for all analytes. Meanwhile, the absorption, distribution, metabolism, excretion (ADME) property was predicted using PreADMET web. The pharmacokinetic parameters indicated that they were absorbed quickly, eliminated rapidly together with high blood concentration. The results of tissue distribution demonstrated that CE was distributed rapidly and widely among tissues, and stomach was the main tissue site of CE and 7‐O‐AC, followed by small intestine/liver. This study indicates that the structures and dosages of active CA should be modified to help improve the absorption rate and residence time, and the findings are helpful for the pharmaceutical design of CA derivatives.