bluuebunny/crossref_metadata_2025_split huggingface dataset:
In the Footsteps of Krste P. Misirkov: Tracing the Roots of Macedonian Sociological Discourse
Authors: Cvetanova Ganka 
Published: November 2024

ABSTRACTMisirkov is one of the most eminent figures in Macedonian national history. He made significant contributions as a Slavist, historian, folklorist, and ethnographer. In his seminal work, “On Macedonian Matters” (1903), Misirkov presented his theoretical and scientific views on the Macedonian question. He made a groundbreaking attempt to standardize the Macedonian language, offering both a linguistic and sociological exploration of its role in establishing political legitimacy for the Macedonian ethnocultural entity. His comprehensive treatment of other critical aspects, including the cultural identity, sense of common belonging, and the need for a separate political unit, aligns with the foundational principles of modern nations. Introducing novel ideas and frameworks, Misirkov significantly contributed to understanding Macedonian ethnocultural distinctiveness, crucial for the nation‐building process. This paper emphasizes Misirkov's overlooked role as the founder of Macedonian sociological discourse, drawing parallels with modernist theories about nation and nationalism and analyzing his method through the concept of sociological imagination. Despite the enduring impact of his work, this pioneering aspect remains unexplored in academic research, addressing a significant gap in understanding Misirkov's contributions to Macedonian sociological thought.
Targeting PNPLA3 to Treat MASH and MASH Related Fibrosis and Cirrhosis
Authors: Lindén Daniel , Tesz Gregory , Loomba Rohit 
Published: November 2024

ABSTRACTMetabolic dysfunction‐associated steatotic liver disease (MASLD) is caused by metabolic triggers and genetic predisposition. Among the genetic MASLD risk variants identified today, the common PNPLA3 148M variant exerts the largest effect size of MASLD heritability. The PNPLA3 148M protein is causatively linked to the development of liver steatosis, inflammation and fibrosis in experimental studies and is therefore an appealing target for therapeutic approaches to treat this disease. Several PNPLA3 targeted approaches are currently being evaluated in clinical trials for the treatment of metabolic dysfunction‐associated steatohepatitis (MASH), the most severe form of MASLD and promising proof of principle data with reduced liver fat content in homozygous PNPLA3 148M risk allele carriers has been reported from phase 1 trials following hepatic silencing of PNPLA3. Thus, targeting PNPLA3, the strongest genetic determinant of MASH may hold promise as the first precision medicine for the treatment of this disease. A histological endpoint‐based phase 2b study has been initiated and several more are expected to be initiated to evaluate treatment effects on histological MASH and liver fibrosis in participants being homozygous for the PNPLA3 148M risk allele variant. The scope of this mini‐review is to briefly describe the PNPLA3 148M genetics, function and preclinical experimental evidence with therapeutic approaches targeting PNPLA3 as well as to summarise the PNPLA3 based therapies currently in clinical development.
Fossil insect‐feeding traces indicate unrecognized evolutionary history and biodiversity on Australia's iconic Eucalyptus
Authors: Giraldo L. Alejandro , Wilf Peter , Donovan Michael P. , Kooyman Robert M. , Gandolfo Maria A. 
Published: November 2024

Summary

Fossilized plant–insect herbivore associations provide fundamental information about the assembly of terrestrial communities through geologic time. However, fossil evidence of associations originating in deep time and persisting to the modern day is scarce.

We studied the insect herbivore damage found on 284 Eucalyptus frenguelliana leaves from the early Eocene Laguna del Hunco rainforest locality in Argentinean Patagonia and compared damage patterns with those observed on extant, rainforest‐associated Eucalyptus species from Australasia (> 10 000 herbarium sheets reviewed).

In the fossil material, we identified 28 insect herbivory damage types, including 12 types of external feeding, one of piercing‐and‐sucking, five of galls, and 10 of mines. All 28 damage types were observed in the herbarium specimens.

The finding of all the fossil damage types on extant Eucalyptus specimens suggests long‐standing associations between multiple insect herbivore lineages and their host genus spanning 52 million years across the Southern Hemisphere. This long‐term persistence, probably enabled through niche conservatism in wet eucalypt forests, demonstrates the imprint of fossil history on the composition of extant insect herbivore assemblages. Although the identities of most insect culprits remain unknown, we provide a list of Eucalyptus species and specific population locations to facilitate their discovery, highlighting the relevance of fossils in discovering extant biodiversity.
Update on Current Knowledge of Paediatric Obstructive Sleep Apnoea: From Animal to Human Studies
Authors: Ono Takashi , Flores‐Mir Carlos 
Published: November 2024

ABSTRACTOrthodontists' interest in paediatric obstructive sleep apnoea (PedOSA) has grown in popularity recently. We have seen growth modification treatment modalities, including maxillary expansion, promising the prevention or cure of PedOSA. Clinical approaches such as palatal expansion and mandibular and maxillary complex advancement have been proposed to manage PedOSA. These hypotheses should be adequately tested before clinical recommendations are formulated. This review aimed to narratively synthesise our current understanding of PedOSA management with craniofacial growth modification alternatives. Basic research on the biological basis of PedOSA has been conducted in animal models. Laboratory‐based PedOSA studies wish to provide insight into the molecular biological mechanisms by which human PedOSA affects growth‐associated structural and emotional growth and development. In the proposed IH animal model, mandibular growth (especially posterior anteroposterior and transverse dimensions) and condylar head bone density were more sensitive to IH exposure in adolescents but less in juvenile rats. Nevertheless, clear‐cut statistical growth differences were limited. This suggests that IH, in this rat model, influenced mandibular morphology and metabolism later than earlier craniofacial growth stages. No impact was found for the maxillofacial complex in any plane of space. The existing human studies on the causes, risk factors, consequences, symptomatology, diagnosis and effects of PedOSA are discussed. However, there is a pressing need for further research to clarify whether craniofacial disturbances are consequences or facilitators of PedOSA. Several hypotheses about the potential impact of impaired craniofacial growth as a facilitator for PedOSA currently circulate.
Biogenic silver nanoparticles derived from the marine brown algae Iyengaria stellata for plant growth promotion under saline conditions
Authors: Patel Disha , Patel Bhakti , Patani Anil , Yadav Virendra Kumar , Alharbi Sulaiman Ali , Alarfaj Abdullah A. , Choudhary Nisha , Patel Ashish 
Published: November 2024

AbstractIn the green approach for nanoparticle synthesis, biomolecules like phenols, alkaloids, proteins, enzymes, and lipids are the prime reducing and stabilizing agents. In this study, we reported the synthesis of silver nanoparticles (AgNPs) using the aqueous extract of the marine algae Iyengaria stellata (Børgesen) for the first time. The characterization study showed that the developed AgNPs were spherical in shape and their average particle size was 60 nm. The UV–visible spectrum of AgNPs showed strong surface plasmon resonance (SPR) near 425 nm, whereas the Fourier transform infrared spectroscopy (FTIR) spectrum revealed the presence of several functional groups like amines, nitriles, hydroxyl, and carbonyl groups on the nanoparticle surface, which confirms the involvement of algal metabolites in the reduction and stabilization of AgNPs. The X‐ray diffraction (XRD) analysis provided information about the crystallinity of developed nanoparticles, and the crystallite size of AgNPs was calculated to be 33 nm using the Scherrer equation. The algal synthesized AgNPs examined for their impact on growth of tomato seeds under salt stressed conditions showed significant enhancement in growth parameters like leaf area, shoot height, root length, shoot weight, and root weight. Also, a reduction in biochemical stress responses such as chlorophyll content, relative water content, electrolyte leakage, hydrogen peroxide (H2O2) content, glycine betaine content, and proline content was seen. This study suggests that algal synthesized AgNPs can reduce the effect of salt stress in tomato plants and promote their overall growth.
Assessing Input Legitimacy of Occupational Pensions in Europe
Authors: Mayer Thomas , Wiß Tobias 
Published: November 2024

ABSTRACTAs private asset‐based welfare like funded occupational pension schemes gain importance, legitimacy concerns arise due to financial market downturns and low investment returns. This paper assesses their input legitimacy by distinguishing between individual‐direct and collective‐representative input possibilities in decision‐making processes. We argue that individual‐direct input possibilities decrease while collective‐representative input possibilities increase with occupational pensions' compulsion. To test these hypotheses, we compare voluntary occupational pension schemes in Austria, Spain, and Ireland with (quasi‐)mandatory schemes in the Netherlands and Denmark, using Germany as a test case due to recent reforms enhancing their importance. Our institutional analysis and novel survey reveal that compulsory occupational pensions are associated with lower individual‐direct and higher collective‐representative input possibilities. These findings underscore the critical role of participatory procedures in establishing legitimacy in private governance, suggesting they may strengthen public trust and satisfaction with non‐state governance.
The effect of screening for publication bias on the outcomes of meta‐analyses
Authors: Michael Haben 
Published: November 2024

AbstractConducting a meta‐analysis on a body of studies subject to publication bias is a type of post‐selection inference that may invalidate findings. Therefore, analysts often run a hypothesis test to check for publication bias prior to conducting a meta‐analysis. However, conducting meta‐analyses conditional on the outcome of such preliminary tests is itself a form of post‐selection inference. We investigate the effect on the outcome of a meta‐analysis of a null finding at the preliminary stage. We find that in many situations there is no or little bias in the findings at the main stage.
Temporal patterns of Veteran suicide: Variation by season, day of the week, and holidays
Authors: Gold Sarah A. , Goodrich Molly , Morley Sybil W. , Stephens Brady , McCarthy John F. 
Published: November 2024

AbstractPurposeTo assess temporal patterns of Veteran suicide deaths from 2001 to 2021.MethodsData from Veterans Affairs (VA) and Department of Defense (DoD) administrative sources and the VA/DoD Mortality Data Repository identified 133,867 Veteran suicides from 2001 to 2021. Incidence Rate Ratios (IRRs) and Joinpoint regression assessed patterns of Veteran suicide across seasons, days of the week, and 14 holidays; overall and by sex and age.ResultsIncidence of Veteran suicide was highest in summers and on Mondays. Veteran suicide incidence was lower on six holidays: Martin Luther King Jr. Day (IRR = 0.82, 95% CI = 0.73–0.93), Presidents' Day (IRR = 0.88, 0.78, 0.99), Memorial Day (IRR = 0.89, CI = 0.79–0.99), Labor Day (IRR = 0.88, CI = 0.78–0.98), Thanksgiving (IRR = 0.81, CI = 0.71–0.92), and Christmas (IRR = 0.78, CI = 0.68–0.89). Suicide incidence was elevated on New Year's Day (IRR = 1.17, CI = 1.05–1.31), particularly among Veterans 25–34 years old (IRR = 1.64, CI = 1.19–2.26). An increasing trend in daily average suicides was indicated from December 30th to January 1st (β = 1.79, p < 0.05). Both seasonal and day of the week effects were present in most subpopulations. Holiday effects were most prevalent among men and varied by age.ConclusionsVeteran suicide incidence was elevated in summer months, on Mondays, and on New Year's Day. Temporal patterns differed by sex and age. Findings can inform ongoing Veteran suicide prevention efforts.
Remote Sensing as a Convergent Discipline: A Path Forward
Authors: Lippitt Christopher D. 
Published: November 2024

ABSTRACTSince its inception, remote sensing has evolved from informing military and natural resource management decisions to addressing a broad spectrum of information deficits about environmental phenomena in support of myriad sciences, industries, and management priorities. Driven by changing information requirements and the advancement of technology, geographers, physicists, statisticians, and many others developed a shared understanding of the problem of extracting reliable information from the patterns of electromagnetic radiation observed by radiometers and other electromagnetic sensors, a shared understanding that is now manifest in professional societies, academic journals, and specialized training programs around the world. The discipline we call remote sensing is now uniquely positioned to play a principal role in a new convergent project oriented around the vexing problem of informing humanity's response to a rapidly shifting climate and the 6th mass extinction. Remote sensing, artificial intelligence, computer vision, and robotics each make substantial contributions to this problem, but language, standards, and practices vary widely. The proliferation of sensors now deployed in the environment as part of the internet‐of‐things (e.g., modern cars, satellite constellations, smartphones, CCTV, and trail cameras), coupled with rapid advancements in machine learning and the proliferation of communication networks, makes the potential for persistent, robust, and largely autonomous environmental monitoring systems clear, but also points to the pressing need to converge around a shared understanding of the problem.
Residual Stress Calculation of Hydraulic Autofrettage Thick-Walled Tube Based on a Revised Kinematic Hardening Model
Authors: Zhang Zhao , Yang Gang , Wang Xuesheng , Chen Qinzhu 
Published: November 2024

Abstract
The current theoretical calculation methods for autofrettage of thick-walled tube do not adequately consider the change in the stress–strain relationship of the material with the maximum loading strain. This deficiency has an adverse impact on the accuracy of the residual stress calculation after autofrettage. In this paper, the revised kinematic hardening model is adopted to take change of the stress–strain relationship of the material in the compression section after different maximum tensile strains into consideration. Furthermore, power function is used to express the stress–strain relationship in the plastic section in both the tensile and compressive plastic parts. A new calculation method for the autofrettage residual stress of the hydraulic thick-walled straight tube is came up with through this method. This method enhances the precision of autofrettage residual stress calculations without undue increase of the computational burden. In comparison to the finite element method results utilizing identical material data, the proposed model exhibits enhanced calculation precision, particularly with regard to the stress distribution on the inner surface, surpassing by at least 5% in terms of calculation accuracy than existing calculation methods. Furthermore, the accurate autofrettage residual stress on the inner surface of thick-walled straight tubes obtained through theoretical calculations is of paramount importance for fatigue design of autofrettage thick-walled vessels.
Rotary Displacement Pump With a Sinusoidal Working Chamber and Oscillating Pistons
Authors: Myhan Ryszard 
Published: November 2024

Abstract
This article critically analyzes the structural design of a rotary positive displacement pump described in two patent applications. The general description of the pump in the patent applications is the main reason why the examined solution has not found practical applications to date. The shape of the inner contour of the pump's housing has been described in detail in the proposed solution. The analysis demonstrated that an odd number of pendulum blocks is required and that the number of blocks is determined by the division module of the inner contour of the pump's housing (number of depressions in the wavy surface). The diameter of the cylindrical cross section of a pendulum block and the guiding radius between the axis of the pendulum block and the rotor's axis of rotation were optimized based on the proposed pump geometry. The goal of the optimization process was to minimize clearance as a measure of the pump's internal leak tightness. The estimated optimal values were used to simulate the pump's full operating cycle, depending on the nominal diameter, division module, and the shape factor of pump housing. The results of the simulation indicate that the described solution could have many practical applications. However, the described geometric relationships have to be maintained, and the number of pendulum blocks, the guiding radius, and piston diameter have to be optimized for the needs of specific applications.
The Role of Artificial Intelligence in Improving Histopathological Diagnosis of Prostate Cancer: A Review
Authors: Afifi Shereen , Faragallah M. Hamdy , Taha Radwa , Baig Mirza , Ullah Ehsan , Gholam Hosseini Hamid , Hassanein Sally I. 
Published: November 2024

Abstract
This review investigates the effectiveness of exploiting the massive Artificial Intelligence (AI) technology in the diagnosis of prostate cancer histopathological images. It focuses on studying and analyzing the current state and practice for utilizing AI tools, including significant machine learning and deep learning models in the histopathological image analysis process. The preferred reporting items for systematic reviews and meta-analyses (PRISMA) methodology was adopted for conducting this systematic review to include recent research articles that have been published since 2017. Leveraging novel deep learning models and advanced imaging techniques, AI demonstrates promising capabilities in improving accuracy and efficiency in detecting and classifying prostate cancer. A comprehensive comparison of existing works has been presented with in-depth discussions around current limitations and key challenges while proposing some future advancements. This study aims to pave the way for future research and further integration of AI into the diagnostic processes toward early detection, personalized treatment strategies, and enhanced patient outcomes in the context of a prostate cancer diagnosis.
On-Orbit Processing and Hardware Performance of Microgravity Hydrothermal Synthesis for Graphene Aerogel
Authors: Li Zhou , Ozbakir Yaprak , Frick Jessica J. , Ormsby Rachel , Scherzer Christopher , Liu Chen , Cox Jasmine M. , Carraro Carlo , Maboudian Roya , Senesky Debbie G. 
Published: November 2024

Abstract
This study reports on the hydrothermal synthesis of graphene hydrogels (GHs) under microgravity on the International Space Station (ISS), using a custom-designed autoclave compatible with NASA's Solidification Using a Baffle in Sealed Ampoules (SUBSA) furnace. Extensive long-term stability tests of graphene oxide (GO) dispersion and GHs in deionized (DI) water were performed to verify their compatibility with the custom-designed autoclaves before launching to the ISS. Eight ampoules (2 autoclaves each, totaling 16 samples) filled with GO dispersion were launched to the ISS and heated to trigger the gelation reaction to synthesize GHs. The effectiveness of the designed leak-before-burst (LBB) safety technology for controlling the pressure inside the autoclave under safety requirements was demonstrated during the heating process on the ISS through the release of water vapor. For comparison, another eight ampoules filled with the GO dispersion were heated at the same temperature on Earth, resulting in 16 total control samples to analyze the effects of microgravity on the multiphysical properties of graphene aerogels (GAs). Both sets of GH samples prepared on the ISS and on Earth were transformed into GAs via solvent exchange to ethanol at ambient conditions, followed by critical point drying using carbon dioxide. Raman spectroscopy and scanning electron microscope (SEM) confirmed the successful synthesis of GAs on the ISS. As a continuation of the work, further characterization experiments are underway to comprehensively analyze the multiphysical properties of the graphene aerogels upon synthesis under microgravity conditions.
A Critical and Comparative Study of Layered Cylindrical Hollow Roller Bearing Using Numerical and Experimental Analyses for the Assessment of Static Load Carrying Capacity
Authors: Solanki Mitul T. , Vakharia Dipak P. 
Published: November 2024

Abstract
The fatigue life of rolling bearings is a critical factor in their selection and application, driving ongoing research aimed at enhancing their performance. Among the solutions explored, the introduction of hollow rollers has been noted for their lighter weight and reduced stress. However, experimental results have shown that hollow rollers can suffer catastrophic failures under low static loading conditions. Recent studies have demonstrated that layered cylindrical hollow rollers (LCHRs) outperform both conventional solid and hollow cylindrical rollers under similar loading conditions. This warrants further investigation into the potential benefits of LCHR. This study aims to estimate the static load carrying capacity of LCHR bearing in comparison to hollow cylindrical roller bearings having different hollowness percentage. Corrected experimental results from individual roller-on-plate tests showed excellent agreement (within 5%) with numerical analyses, validating the numerical approach. Key parameters such as von Mises stress, contact pressure, bending stress, and contact width were obtained through numerical analysis. Additionally, a static load test rig was designed and developed to estimate the static load carrying capacity of the bearings under examination. The results of full bearing sample tests for various roller types corroborated the individual roller-on-plate test findings. The observed superior static load carrying capacity and promising semi-contact width of LCHR indicate their potential for extended fatigue life compared to solid and hollow rollers.