bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE MUSTAHIQ EMPOWERMENT MODEL: A COLLABORATION BETWEEN SHARIA BANK AND OPZ IN OPTIMIZING ZAKAT FUNDS
Authors: Manggala Putri Syah Amelia , Firmansyah Eka Jati Rahayu , Hamid Homaidi 
Published: June 2019

Purpose of the study: To find a Zakat fund management scheme based on sharia banking for sustainable mustahiq empowerment.
Methodology: This research is qualitative research using grounded theory method.
Main Findings: Zakat funds collected are used as collaterals for deposits for the development of mustahiq businesses. The profit sharing ratio from the deposits will reduce the mustahiq installment expense. While deposit guarantees will make mustahik get financing easily from Islamic banking.
Applications of this study: The research findings can be used in studies on productive zakat, philanthropic studies and the development of Islamic banking.
Novelty/ Originality of this study: With this model, mustahik which is not bankable will receive financing for business development. On the other hand, mustahik will get payments in installments so that it will ease the burden.
HALAL TOURISM: DEVELOPMENT, CHANCE AND CHALLENGE
Authors: Satriana Eka Dewi , Faridah Hayuun Durrotul 
Published: June 2019

The tourism sector is one sector that is able to increase employment and increase economic growth. At present, halal tourism is starting to become popular. This is in line with the increase in Muslim tourists from year to year. The development of halal tourism began to be carried out by various countries, muslim and non-muslim countries. This article will explore the development of halal tourism in several countries, reviewing the concepts and principles of halal tourism, and discuss the chances and challenges.
IDENTIFICATION OF ALCOHOL CONTENT IN MEDICINES AT THE PHARMACY THROUGH OBSERVATION ON SECONDARY PACKAGING
Authors: Rahem Abdul 
Published: June 2019

Demand of halal medicine in the world is an interesting issue to be discussed, considering that there are still many medicines that are intended to contain impermissible (haram) ingredients. The halal medicine depends on the active ingredients and additives of medicine, including the production process and storage of medicine. Alcoholic medicine are a polemic in the community, especially about halal medicine. This study aims to identify the alcohol content of syrup preparations in Yakersuda Pharmacy of Bangkalan. An observational study was conducted to observe alcohol content on secondary medicine packaging. The results showed that there were 8 (eight) items of medicine which listed the alcohol content in the secondary packaging, namely: Actifed Plus Dry Cough + Colds with alcohol content (9.9%); Actifed Plus Expektoran (6.93%); Benacol DTM (4%); Benacol Syr (4%); OBH Combi Syr Phlegm (2%); Vicks formula 44 (10%); and Woods Exp Syr (6%). The conclusion is alcohol content in medicine at the Yakersuda Pharmacy more then 1%. Medicines that do not include the composition of alcohol cannot be sure the drug is alcohol free.
Prevalensi Parasit Cacing Saluran Pencernaan Pada Kucing Liar di Kota Banyuwangi
Authors: Yudhana Aditya , Praja Ratih Novita 
Published: June 2019

Penelitian ini bertujuan untuk mengetahui angka prevalensi kasus infeksi cacing saluran cerna dan mengidentifikasi jenis cacing pada kucing liar di wilayah Kota Banyuwangi. 126 sampel feses kucing yang berasal dari wilayah Kota Banyuwangi dikoleksi dan disimpan dalam larutan formaldehide 10%. Seluruh sampel feses tersebut diperiksa dengan dua metode berbeda yaitu metode natif dan metode pengapungan untuk mengidentifikasi telur cacing yang terdapat pada feses kucing. Pada penelitian ini teridentifikasi tiga genus cacing yang menginfeksi kucing liar di wilayah Kota Banyuwangi yaitu Toxocara, Ancylostoma, dan Diphyllobothrium. Hasil penelitian ini menunjukkan bahwa prevalensi kasus infeksi cacing saluran cerna pada kucing liar wilayah Kota Banyuwangi masih tinggi, yaitu Toxocara Spp (43,65%), Ancylostoma Spp (3,96%), dan Diphyllobothrium Spp (52,38%). Untuk itu diperlukan program pengendalian yang tepat terhadap kasus infeksi cacing saluran cerna pada kucing liar di wilayah Kota Banyuwangi.
Functional Electrical Stimulation‐Assisted Cycle Ergometry in Critically Ill. Protocol of Randomised Controlled Trial
Authors: Waldauf Petr , Gojda Jan , Urban Tomáš , Hrušková Natália , Blahutová Barbora , Hejnová Marie , Jiroutková Kateřina , Fric Michal , Jánský Pavel , Kukulova Jana , Stephens Francis , Řasová Kamila , Duška František 
Published: June 2019

Abstract
Intensive care unit-acquired weakness is the most important cause of failed functional outcome in survivors of critical care. Most damage occurs during the first week when patients are not cooperative enough with conventional rehabilitation. Functional-electrical stimulation-assisted cycle ergometry (FES-CE) applied within 48 of ICU admission may improve muscle function and long-tem outcome. Methods: Assessor-blinded pragmatic single-centre randomized controlled trial. Adults (n=150) mechanically ventilated for <48 hours from 4 ICUs who are estimated to need >7 days of critical care will be randomized (1:1) to receive either standard of care or FES-CE-based intensified rehabilitation, which will continue until ICU discharge. Primary outcome: Quality of life measured by SF-36 score at 6 months. Secondary outcomes: functional performance at ICU discharge, muscle mass (vastus ultrasound, N-balance) and function (MRC score, insulin sensitivity). In a subgroup (n=30) we will assess insulin sensitivity and perform skeletal muscle biopsies to look at mitochondrial function, fibre typing and regulatory proteins expression.
Capsular Warning Syndrome: Clinical Analysis and Treatment
Authors: He Lanying , Xu Ronghua , Wang Jian , Zhang Lili , Zhang Lijuan , Zhou Fangfang , Dong Weiwei 
Published: June 2019

Abstract
Background: Capsular warning syndrome (CWS) was a rare clinical syndrome, which was defined as recurrent transient lacunar syndromes. The mechanism and clinical management of CWS were not clear. The purpose of this study was to discuss the clinical characteristics, treatment and prognosis of the CWS.
Methods: This was a multicenter retrospective study that involved three medical centers, we collected clinical data from patients with CWS between January 2013 and December 2018. We analyzed the clinical characteristics of the CWS. Patients with CWS were divided into two groups: rt-PA and no rt-PA groups. We analyzed the therapeutic effects and prognosis between different groups.
Results: This study included 72 patients, 27 in rt-PA group, 45 in no rt-PA group, hypertension and dyslipidemia were the most common risk factors. The mean number of episodes before an irreversible neurological impairment or the symptoms completely disappeared was 5 times(3-11). 59 (81.94%) patients had acute infarction lesions on the diffusion weighted imaging (DWI). The most common infarct location was the internal capsule (76.38%,55), followed by the thalamus and pons. The difference in therapeutic effects between rt-PA, single and double antiplatelet groups was not significant(P>0.05). A good prognosis was observed in 61 (84.72%) patients at 3-month, 23 (23/27, 85.19%) patients in rt-PA group and 38 (38/45,84.44%) patients in no rt-PA group(P>0.05). After 3 months of follow-up, 2 patients had recurrent ischemic stroke.
Conclusions: The most effective treatment of CWS remains unclear. Despite the high incidence of infarction in CWS patients, more than 80% patients had favorable functional prognosis
Four collateral circulation pathways were observed after common carotid artery occlusion
Authors: Wang Jianan , Zheng Chengrong , Hou Bei , Huang Aihua , Zhang Xiongwei , Du Bin 
Published: June 2019

Abstract
Background: Common carotid artery (CCA) occlusion (CCAO) is a rare condition. Owing to collateral circulation, ipsilateral internal carotid artery (ICA) and external carotid artery (ECA) are often patent.
Methods: This study included 16 patients with unilateral CCAO and patent ipsilateral ICA and ECA. The pathways which supplied ICA were investigated by digital subtraction angiography (DSA), transcranial Doppler (TCD), magnetic resonance angiography (MRA) and computed tomography angiography (CTA).
Results: TCD found antegrade blood flow in ipsilateral ICA in all 16 patients, which was supplied by retrograde blood flow in ipsilateral ECA through carotid bifurcation. We call this phenomenon “ICA steal”. DSA and CTA discovered four pathways of ICA steal, including 1) ipsilateral vertebral artery – occipital artery – ECA – ICA, 2) ipsilateral thyrocervical trunk or costocervical trunk – ascending cervical artery or deep cervical artery – occipital artery – ECA – ICA, 3) contralateral ECA – contralateral superior thyroid artery – ipsilateral superior thyroid artery – ipsilateral ECA – ICA, and 4) ipsilateral thyrocervical trunk – inferior thyroid artery – superior thyroid artery – ECA – ICA.
Conclusions: ICA is possible to be patent and supplied by several collateral circulation pathways after CCAO.
Surveying the Prevalence of Lower Urinary Tract Symptoms Based on Individual and Clinical Parameters in Patients with Multiple Sclerosis
Authors: Nazari Fatemeh , Shaygannejad Vahid , Sichani Mehrdad Mohammadi , Gharaagozlou Marjan Mansourian , Hajhashemi Valiollah 
Published: June 2019

Abstract
Background

Most patients with multiple sclerosis (MS) suffer from bladder dysfunction during the course of the disease. This study was conducted to examine the prevalence of these complications among patients with MS.

Methods

This cross-sectional study was performed on 603 patients with MS who referred to the neurology clinics of Kashani and Alzahra Hospitals affiliated to Isfahan University of Medical Sciences, Isfahan, Iran. The sampling was performed by multi-stage random cluster sampling method and the informed consent form was filled in by the subjects. Then, all the data were collected through interviews using the Lower Urinary Tract Symptom Score (LUTSS) developed in accordance with the definitions presented by the International Continence Society (ICS) and the International Prostate Symptom Score (I-PSS). The data were analyzed using descriptive and inferential statistical tests in SPSS and the significance level was considered to be less than 0.050.

Results

The prevalence rate of lower urinary tract symptoms (LUTS) was 87.6% among all the subjects, with a similar rate among women (88.0%) and men (86.0%). There was a significant difference between the two groups of men and women in terms of the prevalence of stress urinary incontinence (SUI), intermittent urine flow, hesitancy, straining, and dribbling (P < 0.050). There was no significant difference between the two groups of women and men in terms of the prevalence of other symptoms (P > 0.050). Moreover, there was a significant difference between the degree of LUTS with age, marital status, education, duration of illness, clinical course, and disability (P < 0.05).

Conclusions

A high prevalence of LUTS was found among patients with MS, with similar rates in men and women, and the nature of the urinary complaints and LUTS was different among men and women with MS. Therefore, it is recommended that the health system take necessary measures regarding timely detection and treatment of LUTS among these patients in order to prevent secondary outcomes and improve the quality of life (QOL) of patients with MS.
Increased C-reactive protein levels in participants with frequent headache. The HUNT Study 2006-2008
Authors: Hagen Knut , Stovner Lars Jacob , Nilsen Kristian Bernhard , Winsvold Bendik Slagsvold 
Published: June 2019

Abstract
Background Increased high sensitivity C- reactive protein (hs-CRP) levels have been found in many earlier studies on migraine, and recently also in persons with migraine and insomnia. The aim of this study was to see whether these findings could be reproduced in a large-scale population-based study.
Methods A total of 50,807 (54%) out of 94,194 invited aged ≥ 20 years or older participated in the third wave of the Nord-Trøndelag Health Study study performed in 2006-2008. Among these, 38,807 (41%) had valid measures of hs-CRP and answered questions on headache and insomnia. Elevated hs-CRP was defined as >3.0 mg/L. The cross-sectional association with headache was estimated by multivariate analyses using multiple logistic regression. The precision of the odds ratio (OR) was assessed with 95% confidence interval (CI).
Results In the fully adjusted model, elevated hs-CRP was associated with migraine (OR 1.14, 95% CI 1.04-1.25) and migraine with aura (OR 1.15, 95% CI 1.03-1.29). The association was stronger among individuals with headache ≥ 7 days/month for any headache (OR 1.19, 95% CI 1.08-1.31), migraine (OR 1.30, 95% CI 1.10-1.54), migraine with aura (OR 1.47, 95% CI 1.20-1.80), and other headaches (OR 1.16, 95% CI 1.03-1.30). No clear relationship was found between elevated hs-CRP and headache less than 7 days/month or with insomnia.
Conclusions Cross-sectional data from a large-scale population-based study showed that elevated hs-CRP was associated with headache ≥ 7 days/month, especially frequent migraine with aura.
Experiences of people with Multiple Sclerosis using textured insoles: an interpretive phenomenological exploration
Authors: Baron Yael Jennifer , Hatton A. , McKeon P. O. , Rome K. , Martin D. , Dixon J. 
Published: June 2019

Abstract
Background

Impaired balance and mobility is one of the most concerning symptoms experienced by people with Multiple Sclerosis as it reduces their independence. It can be caused by reduced plantar sensation. Textured insoles may have the potential to improve balance and mobility by increasing plantar sensory input but their acceptability has not been investigated. This study aimed to investigate the experience of people with Multiple Sclerosis who wore textured insoles in free living for three months.

Method

A qualitative study embedded within an exploratory randomised controlled trial. Seven participants with Multiple Sclerosis who were ambulatory with a unilateral walking aid were identified from a larger group in a study into the effects of textured insoles on balance and mobility. Participants who wore textured insoles for three months in free living were recruited to participate in focus groups or individual semi-structured interviews about their experience of wearing the insoles. Themes in the data were identified using interpretive phenomenological analysis.

Results

Three overarching themes were identified from transcribed data; perceived benefit of the insoles, comfort of the insoles and participants’ awareness of their feet. Participants’ experiences were individual; some found the insoles beneficial and experienced increased mobility confidence whilst others did not. Several participants experienced increased awareness of their foot position. Only those participants who experienced benefits from wearing the insoles would continue to engage with them as an intervention.

Conclusions

Participants reported different experiences of wearing textured insoles, some experienced significant benefits to mobility confidence and awareness of their feet whilst others did not experience any benefit.

Trial registration

ISRCTN reference number ISRCTN85766784, date of registration 7th April 2014.
https://doi.org/10.1186/ISRCTN85766784
Transcriptomic analysis of Verbena bonariensis roots in response to cadmium stress
Authors: Wang Meng-qi , Bai Zhen-yu , Xiao Ya-fang , Li Yan , Liu Qing-lin , Zhang Lei , Pan Yuan-zhi , Jiang Bei-bei , Zhang Fan 
Published: June 2019

Abstract
Background: Cadmium (Cd) has caused serious heavy metal (HM) pollution in the soil and finding suitable plants to remediate HM pollution is an environmentally friendly approach. Verbena bonariensis is a kind of garden plant with excellent ornamental, good environmental adaptability, which has great potential for future development. This study firstly reported Cd tolerance and an overall analysis of transcriptome in V. bonariensis.
Results: In this study, the tolerance of V. bonariensis to Cd stress was investigated in four ways, including germination, growth response, physiological and molecular changes. The results showed that V. bonariensis is not a hyperaccumulator, but it is tolerant to Cd and has the ability to enrich Cd. In the transcriptome data of V. bonariensis roots under Cd stress, 237, 866 transcripts and 191, 370 unigenes were constructed. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that differentially expressed genes (DEGs) under Cd stress are predominately involved in cell structure, ROS scavenging system, chelating reaction and secondary metabolites, transpiration and photosynthesis. DEGs encoding lignin synthesis, chalcone synthase (CHS) and anthocyanidin synthase (ANS) were prominent in V. bonariensis response to Cd stress. The expression patterns of 10 DEGs, validated by quantitative real-time PCR (qRT-PCR), were highly accordant with the RNA-seq results. This study provided novel strategies for further studies on tolerance to Cd exposure and functional genomics in V. bonariensis，which was useful information in improving molecular breeding to Cd and phytoremediation.
Addressing Patient-Reported Barriers to Advance Care Planning in Family Practice
Authors: Bernard Carrie , Tan Amy , Slaven Marissa , Elston Dawn , Heyland Daren K. , Howard Michelle 
Published: June 2019

Abstract
Background

Although patient-centred care has become increasingly important across all medical specialties, when it comes to end of life care, research has shown that treatments ordered are not often concordant with people’s expressed preferences. Patient and family engagement in Advance Care Planning (ACP) in the primary care setting could improve the concordance between patients’ wishes and the healthcare received when patients cannot speak for themselves. The aim of this study was to better understand the barriers faced by older patients regarding talking to their family members and family physicians about ACP.

Methods

In this multi-site cross-sectional study, three free text questions regarding reasons patients found it difficult to discuss ACP with their families or their family physicians were part of a self-administered questionnaire about patients’ knowledge of and engagement in ACP. The questionnaire, which included closed ended questions followed by three probing open ended questions, was distributed in 20 family practices across 3 provinces in Canada. The free text responses were analyzed using thematic content analysis and form the basis of this paper.

Results

102 participants provided an analyzable response to the survey when asked why they haven’t talked to someone about ACP. 254 answered the question about talking to their physician and 340 answered the question about talking to family members. Eight distinct themes emerged from the free text response analysis: 1. They were too young for ACP; 2. The topic is too emotional; 3. The MD should be responsible for bringing up ACP 4. A fear of negatively impacting the patient-physician relationship; 5. Not enough time in appointments; 6. Concern about family dynamics; 7. It’s not a priority; and 8. A lack of knowledge about ACP.

Conclusions

Patients in our sample described many barriers to ACP discussions, including concerns about the effect these discussions may have on relationships with both family members and family physicians, and issues relating to patients’ knowledge and interpretation of the importance, responsibility for, or relevance of ACP itself. Family physicians may be uniquely placed to leverage the longitudinal, person- centred relationship they have with patients to mitigate some of these barriers.
Comparison of refractive stability and myopic regression after photorefractive keratectomy with different optical zones using Mel 90 excimer laser
Authors: Shin Dae Hwan , Lee Yong Woo , Choi Chul Young 
Published: June 2019

Abstract
Background: To compare the changes in clinical outcomes and the degree of regression between a 6.0 mm optical zone (6.0 OZ) and 6.5 mm optical zone (6.5 OZ) following photorefractive keratectomy (PRK).
Methods: The records of 95 eyes that had undergone PRK with a 6.0 OZ (n = 40) and a 6.5 OZ (n = 55) were retrospectively reviewed. We compared data including the spherical equivalent of manifest refraction (SE of MR), simulated K (Sim K), thinnest corneal thickness, change in thinnest corneal thickness (the initial value divided by corrected diopter [ΔTCT/CD]), Q value, corneal higher order aberrations (HOAs) and spherical aberration (SA) pre-operation, at 3 and 6 months postoperative and at the last follow-up visit (Mean; 20.71 ± 10.52, 17.47 ± 6.57 months in the 6.0 and 6.5 OZ group, respectively).
Results: There were no significant differences in the SE of MR, Sim K and UCVA between the 6.0 OZ group and the 6.5 OZ group over 1 year of follow-up after PRK, and the 6.0 OZ group required less ΔTCT/CD than the 6.5 OZ group. The 6.5 OZ group showed better results in terms of post-operative HOAs of RMS, SA and Q value. When comparing that pattern of change in Sim K, there was no significant difference between the 6.0 OZ group and the 6.5 OZ group.
Conclusions: The clinical refractive outcomes and regression after PRK using Mel 90 excimer laser with a 6.0 OZ were comparable to those with a 6.5 OZ.
Application of the critical incident technique in refining an initial programme theory
Authors: Cunningham Una , De Brún Aoife , McAuliffe Eilish 
Published: June 2019

Abstract
Abstract
Introduction
As realist methodology is still evolving, there is a paucity of guidance on how to conduct theory driven interviews. Novice realist researchers can therefore struggle to collect interview data that can make a meaningful contribution to refining their initial programme theory (IPT). In addition, researchers often face challenges when trying to conduct interviews with healthcare staff due to their busy work schedules.
In this case study of team interventions in acute hospital contexts, we explore the benefits of using the Critical Incident Technique (CIT) in order to build and refine an IPT.
Methods
The five steps of the CIT were mapped against realist methods guidance and adapted into an interview framework. Specifications to identify an incident as “critical” were agreed. We embedded probes in the interview framework to confirm, refine and/or refute previous theories synthesised from the literature and to extrapolate new theories.
Seventeen key informants were interviewed and recordings were transcribed and imported for analysis into NViVo software. Using RAMESES guidelines, Context-Mechanism-Outcomes configurations were extrapolated from a total of 31 incidents.
Results
We found that the CIT facilitated construction of an interview format that allowed KIs to reflect on specific positive or negative team interventions. We demonstrate how the CIT strengthened initial programme theory development as it facilitated the reporting of the specifics of team interventions and the contexts and mechanisms characteristic of those experiences. As new data emerged, it was possible to evolve previous theories synthesised from the literature as well as to explore new theories.
Conclusions
Utilising a CIT framework paid significant dividends in terms of the relevance and usefulness of the data for refining the IPT. Adapting the CIT questioning technique helped to focus the KIs on the specifics relating to an incident allowing the interviewers to concentrate on probes to explore theories during the interview process. The CIT interview format therefore achieved its purpose and the interview framework developed can be adapted for other research topics for use within realist methodology

Key words: Critical Incident Interview, Realist, Programme Theory, Team, Intervention, Hospital, Methods