bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perforator Lappen “light” – der Stellenwert des Keystone
Designed Perforator Flap Concept (KDPFC) an der unteren
Extremität
Authors: Schepler Hadrian , Sauerbier Michael , Grabbe Stephan , Rietz Stephan 
Published: April 2019

Zusammenfassung
Einleitung Mit der Originalpublikation des Keystone Designed Perforator
Flap Concepts (KDPFC) von Behan et al. im Jahre 2003 hat der Keystonelappen mit
Fallserien bis zu 300 Lappenplastiken Einzug in die Familie der Perforatorlappen
gehalten. Die Lappenplastik, welche an die Form eines römischen Torbogens
angelehnt ist, basiert auf dem Vorhandensein von Perforansgefäßen. Eine subtile
Präparation der einzelnen Perforatoren ist dabei aber nicht notwendig. Hinzu
kommt die insgesamt simple und rasche operative Vorgehensweise. Der
Anwendungsbereich umfasst, bis auf wenige topografische Ausnahmen, das gesamte
Integument. Die Anzahl aufschlussreicher Publikationen zu Komplikationen,
Nachteilen oder lokalen Einschränkungen sind jedoch, trotz des breiten
Anwendungsspektrums, spärlich.
Methode Anhand einer retrospektiven Analyse von 35 Patienten über einen
Zeitraum von 36 Monaten wurde der Stellenwert des Lappenkonzeptes nach
überwiegender Hauttumorresektion an der unteren Extremität evaluiert. Die
Lappenauswahl orientierte sich an der Defektsituation unter Anwendung der im
Original beschriebenen Lappenvarianten.
Ergebnisse Insgesamt wurden 36 Lappenplastiken an 35 Patienten
durchgeführt. Die Defektgröße betrug im Mittel 21 cm2 (von
2 cm2 bis 100 cm2). Wundheilungsstörungen wurden in 12
Fällen sowie Teil-/Totale Lappenverluste bei 4 Patienten beobachtet. Allerdings
bedurfte nur 1 Patient mit Lappenverlust einer weiteren operativen Intervention.
Alle anderen heilten unter entsprechender Wundbehandlung komplett ab. Patienten
mit blutverdünnender Medikation hatten erstaunlicherweise weniger Komplikationen
(4 von 10), als Patienten ohne entsprechende Antikoagulation. Hier waren es 12
von 25 Patienten. Auffällig war das Auftreten von Komplikationen inklusive der
Lappenverluste (n = 3) bei 7 Patienten, die eine Defektdeckung am distalen
sprunggelenknahen Unterschenkel sowie am Fuß benötigten.
Diskussion Obwohl in einigen Fällen Wundheilungsstörungen auftraten,
stellt das KDPFC insgesamt einen wertvollen Baustein in der rekonstruktiven
Leiter dar. Das Lappenkonzept ist dabei in der Lage zahlreiche andere lokale und
regionale Lappenplastiken, auch bei komplexeren Situationen, ohne
Qualitätsverlust, zu ersetzen. Der distale Unterschenkel und der Fuß sind
Bereiche, an denen das Konzept allerdings nur bedingt anwendbar ist. Komplexere
Lappentechniken scheinen für diese Region aufgrund der höheren Flexibilität und
des Aktionsradius geeigneter.
All-Polyethylene versus Metal-Backed Tibial Components in Total Knee Arthroplasty
Authors: AbuMoussa Samuel , White Charles Cody , Eichinger Josef K. , Friedman Richard J. 
Published: April 2019

AbstractAll-polyethylene tibial (APT) implants were incorporated into the initial design of the first total knee arthroplasty (TKA) systems. Since then, a dynamic shift has taken place and metal-backed tibial (MBT) implants have become the gold standard in TKA. This has mostly been due to the theoretical advantages of intraoperative flexibility and improved biomechanics in addition to the heavy influence of device manufacturers. MBT implant comes not only with a higher cost but also with potential for complications such as osteolysis, backside wear, and thinning of the polyethylene insert, which were not previously seen with APT implant. The majority of studies comparing APT and MBT implants have shown no difference in clinical outcomes and survivorship. Newer studies from the past decade have begun highlighting the economic advantages of APT implant, especially in patients undergoing primary, uncomplicated TKA. Use of APT implants in younger patients and those with a body mass index > 35 has not been extensively studied, but the existing literature suggests the use of APT implant in these cohorts to be equally as acceptable. With modern implant design and instrumentation, rising utilization of TKA along with current and future economic strain on health care, the increased use of APT implant could result in massive savings without sacrificing positive patient outcomes.
Decreasing Incidence of Postoperative Ileus following Total Knee Arthroplasty: A 17-Year Retrospective Review of 38,007 Knee Replacements at One Institution
Authors: Nguyen Bob H. , Bono Olivia J. , Bono James V. 
Published: April 2019

AbstractIleus following total knee arthroplasty is a clinically and financially significant postoperative complication that has not been extensively described in the orthopaedic joint literature. Ileus has been found to occur in 0.7 to 4.0% of patients after total joint arthroplasty. In a 17-year period (2001 fiscal year through 2017 fiscal year) at one institution, we found an incidence of 0.500% (190/38,007) following knee arthroplasty. In addition, the incidence of ileus following total knee arthroplasty (TKA) has drastically declined over this 17-year period, from 1.593% (13/816) in 2001 to 0.120% (4/3,332) in 2017. This decrease may be attributed to a reduction in narcotic use postoperatively, earlier ambulation following surgery, and reduction in length of hospital stay. Though postoperative ileus is not yet a preventable complication, recognition of risk factors may permit earlier intervention to ameliorate some of the morbidity associated with this condition.
Efficacy of Portable Accelerometer-Based Navigation Devices versus Conventional Guides in Total Knee Arthroplasty: A Meta-analysis
Authors: Sun Han , Li Shuxiang , Wang Kun , Wu Guofeng , Zhou Jian , Sun Xiaoliang 
Published: April 2019

AbstractVarious studies have provided different conclusions regarding which component's alignment can be actually improved by a novel portable accelerometer-based navigation device (PAD) compared with the conventional guide (CON); the operative times and clinical outcomes reported by these studies also exhibited incongruity. Thus, this meta-analysis was conducted to evaluate the efficacy of PADs in total knee arthroplasty (TKA). The Web of Science, EMBASE, PubMed, MEDLINE, and Cochrane Library databases were systematically searched. Studies published till July 2018 and comparing PAD with CON in treatment with TKA were identified. Sixteen studies in which 1,551 TKAs were reported were included. Results showed that PAD was significantly superior to CON in reducing tibial component alignment out of ±3 degrees, femoral coronal angle out of ±3 degrees, and overall mechanical alignment out of ±3 degrees. PAD can also help obtain a more accurate result of femoral coronal angle (degree); however, it requires a longer operative time than the CON group. The two groups were comparable in tibial component alignment out of ±2 degrees, tibial component posterior slope out of ±3 degrees, tibial component posterior slope out of ±2 degrees, femoral coronal angle out of ±2 degrees, femoral sagittal angle out of ±3 degrees, femoral sagittal angle out of ±2 degrees, tibial component alignment (degree), tibial component posterior slope (degree), femoral sagittal angle (degree), overall mechanical alignment (degree), blood loss, Knee Society knee score, Knee Society function score, Oxford Knee Score, Short Form-36 physical component score, Short Form-36 mental component score, and range of motion. In conclusion, compared with CON, PAD can help improve the femoral coronal angle as well as decrease the outliers out of ±3 degrees in femoral/tibial coronal angles and overall mechanical alignment. However, PAD did not show significant advantages in tibial and femoral component sagittal angles out of ±3 degrees, various outliers of ±2 degrees, most mean values of component alignments, operative time, and various functional or satisfactory scores.
Deep Brain Stimulation for the Treatment of Juvenile Parkinsonism: Case Report
Authors: Silva Neto Oliveiros de Oliveira e , Sousa Adailson Soares de , José da Silva Ledismar 
Published: April 2019

AbstractJuvenile parkinsonism (JP) is characterized by the clinical manifestation of Parkinson syndrome before the age of 21 years old. This entity is often associated with genetic mutations. After all the possibilities of clinical treatment have been exhausted, surgical treatment is recommended, performed via deep brain stimulation (DBS) in the subthalamic nucleus (STN) or in the internal segment of the globus pallidus (GPi). The present study aimed to report the case of a patient with JP who underwent DBS in the STN with good clinical response. Neuromodulation via DBS is an option for the treatment of JP. However, since this entity is very rare, and even more peculiar when treated surgically, more studies are necessary to evaluate DBS used to control refractory manifestations and levodopa-induced dyskinesia, as well as surgical complications that may occur, aiming to gather more knowledge of the surgical management of JP. Despite the dysarthria after the DBS, the patient presented a satisfactory response regarding the symptoms, corroborated by the Parkinson's Disease Questionnaire (PDQ-39) score, which was 61.19% before the procedure, and decreased to 21.05% 14 months after the DBS.
Aperture and Suspensory Fixation Equally Efficacious for Quadriceps Tendon Graft Fixation in Primary ACL Reconstruction: A Systematic Review
Authors: Crum Raphael J. , de SA Darren , Kanakamedala Ajay C. , Obioha Obianuju A. , Lesniak Bryson P. , Musahl Volker 
Published: April 2019

AbstractThis review is aimed to compare suspensory and aperture quadriceps tendon autograft femoral and tibial fixations in primary anterior cruciate ligament reconstruction (ACL-R), and the clinical outcomes and complication profiles of each fixation method. Greater understanding of the optimal graft fixation technique for quadriceps tendon (QT) autografts may assist surgeons in improving outcomes after ACL-R. PubMed, Embase, and Medline were searched from database inception to September 2017, and again to July 2018, and identified 3,670 articles, 21 studies of which satisfied inclusion/exclusion criteria. Across included studies, 1,155 QT ACL-R patients (mean age, 28.7 years [range, 15–59 years], with mean postoperative follow-up of 36.1 months [range, 3.4–120 months]), were analyzed. Suspensory fixation on both sides demonstrated a higher percentage of patients (81.7%) achieving the highest rating of “A or B” on the International Knee Documentation Committee (IKDC) knee ligament examination form compared with aperture fixation on both sides (67.7%). Moreover, suspensory fixation had a lower side-to-side difference in anterior laxity (1.6 mm) when compared with aperture fixation (2.3 mm). Among studies which reported graft failure, all of which employed aperture fixation, the rate was 3.2%. Across available data, primary ACL-R using QT grafts appears to have successful short-term outcomes with a short-term graft failure rate of 3% independent of fixation method. While there is limited data regarding the comparison of aperture and suspensory soft-tissue quadriceps tendon (SQT) fixation in ACL-R, the findings of this systematic review suggest that suspensory fixation and aperture fixation in both the femoral and tibial tunnels are equally efficacious based on clinical outcome data on IKDC grade and measured laxity. This is a level IV, systematic review study.
Multi-twist polarization ribbon topologies in highly-confined optical fields
Authors: Bauer Thomas , Banzer Peter , Bouchard Frédéric , Orlov Sergej , Marrucci Lorenzo , Santamato Enrico , Boyd Robert W , Karimi Ebrahim , Leuchs Gerd 
Published: April 2019

Abstract
Electromagnetic plane waves, solutions to Maxwell’s equations, are said to be ‘transverse’ in vacuum. Namely, the waves’ oscillatory electric and magnetic fields are confined within a plane transverse to the waves’ propagation direction. Under tight-focusing conditions however, the field can exhibit longitudinal electric or magnetic components, transverse spin angular momentum, or non-trivial topologies such as Möbius strips. Here, we show that when a suitably spatially structured beam is tightly focused, a three-dimensional polarization topology in the form of a ribbon with two full twists appears in the focal volume. We study experimentally the stability and dynamics of the observed polarization ribbon by exploring its topological structure for various radii upon focusing and for different propagation planes.
Observation of ladder-type electromagnetically induced transparency with atomic optical lattices near a nanofiber
Authors: Su Dianqiang , Liu Ruijuan , Ji Zhonghua , Qi Xiaodong , Song Zixuan , Zhao Yanting , Xiao Liantuan , Jia Suotang 
Published: April 2019

Abstract
Tapered nanofiber is an efficient tool for enhancing light–matter interactions. Here, we experimentally demonstrate the ladder-type electromagnetically induced transparency (EIT) in one-dimensional atomic lattices near an optical nanofiber (ONF). A typical EIT signal is well fitted from experimental data according to a semiclassical model and implies a transmission nearly 35%. We investigate the dependence of EIT transmission on the coupling power and its saturation condition. In addition, we show a large fraction of the transmission spectral broadening is induced by lattice effects. Our results may pave the road towards generating correlations and entanglement through four-wave mixing with ONFs, which may facilitate the realization of efficient quantum optical networks.
Huge power factor in p-type half-Heusler alloys NbFeSb and TaFeSb
Authors: Naydenov G A , Hasnip P J , Lazarov V K , Probert M I J 
Published: April 2019

Abstract
NbFeSb is a promising thermoelectric material which according to experimental and theoretical studies exhibits a high power factor of up to 10 mW m−1 K−2 at room temperature and ZT of 1 at 1000 K. In all previous theoretical studies, κ

latt
is calculated using simplified models, which ignore structural defects. In this work, we calculate κ

latt
by solving the Boltzmann transport equation and subsequently including the contributions of grain boundaries, point defects and electron–phonon interaction. The results for κ

latt
and ZT are in excellent agreement with experimental measurements. In addition, we investigate theoretically the thermoelectric properties of TaFeSb. The material has recently been synthesised experimentally, thus confirming the theoretical hypothesis for its stability. This encourages a full-scale computation of its thermoelectric performance. Our results show that TaFeSb is indeed an excellent thermoelectric material which has a very high power factor of 16 mW m−1 K−2 at room temperature and ZT of 1.5 at 1000 K.
Current practices in the delivery of pharmacogenomics: Impact of the recommendations of the Pharmacy Practice Model Summit
Authors: Valgus John , Weitzel Kristin W , Peterson Josh F , Crona Daniel J , Formea Christine M 
Published: April 2019

AbstractPurposeThis report examines and evaluates pharmacogenomics as an emerging science as it relates to the Practice Advancement Initiative and its predecessor the Pharmacy Practice Model Initiative’s consensus statements for optimal pharmacy practice models.SummaryPharmacogenomics is one of many emerging sciences to impact medication management and delivery of patient care. Increasingly, biomarkers are included in drug labeling and can assist pharmacists with personalizing medicine to optimize patient therapies and avoid adverse effects. The 2011 ASHP Pharmacy Practice Model Summit generated a list of 147 consensus statements for optimal pharmacy practice. Of these, 1 statement explicitly describes adjustment of drug regimens based on genetic factors as an essential activity of pharmacist-provided drug regimens, and 9 other statements provide additional support for incorporation of this emerging science into all aspects of patient care provided by pharmacists. We describe 4 institutions that have made significant inroads to implementing pharmacogenomics, to provide a framework and serve as resources for other institutions initiating their own pharmacogenomics implementation journeys.ConclusionThrough prioritized efforts of the pharmacy profession and health care institutions, pharmacogenomics will be disseminated and implemented, and the goal of the Pharmacy Practice Model Initiative’s consensus statements of improving health care using patients’ genetic characteristics will be realized.
Perivascular Hyaluronidase With Alteplase as Treatment for Hyaluronic Acid Thrombosis
Authors: Baley-Spindel Isaac , Villaseñor-Villalpando Eduardo , Márquez-Espriella Cuahutémoc , Rivera-Salgado Ma. Irene , Dávila-Díaz Rodrigo 
Published: April 2019

Abstract

Background
Hyaluronic acid fillers are the second-most commonly performed nonsurgical procedure. Arterial thrombosis is their most devastating complication. Recent research shows that along hyaluronic acid thrombi, a platelet/fibrin thrombus forms in the site of injection. This is not addressed by current management protocols, which focus on perivascular hyaluronidase plus adjuvant strategies to increase blood flow. We experimented with an animal model utilizing both hyaluronidase and a thrombolytic agent for treatment of occlusion.

Objectives
The authors sought to evaluate the efficacy of a combined treatment of hyaluronidase with a thrombolytic agent applied perivascularly to an artery occluded with hyaluronic acid.

Methods
After direct intravascular injection into the femoral artery, rats were randomized to receive one of the following perivascular solutions: saline, hyaluronidase, alteplase, or hyaluronidase + alteplase. Reperfusion, distal bleeding, and microscopic findings were evaluated 4 hours after intervention.

Results
None of the subjects in the control group showed signs of reperfusion. In the hyaluronidase group, 60% reperfused, 10% completely, the rest only partially. In the alteplase group, 50% reperfused partially. In the hyaluronidase + alteplase group, 50% had partial and 50% complete prepermeabilization. Kruskal-Wallis test showed a P &lt; 0.0001 favoring hyaluronidase + alteplase. Microscopic findings were compatible with bleeding rates.

Conclusions
Both hyaluronic acid and red thrombi play a role in the occluded vessel. Perivascular application of hyaluronidase with a thrombolytic agent seems to achieve greater reperfusion rates than either one alone. If proven safe in humans, this strategy could make treatment more effective while still being suitable for an outpatient setting.
The Impact of Skin Care Product Sales in an Aesthetic Plastic Surgery Practice
Authors: Austin Ryan E , Ahmad Jamil , Lista Frank 
Published: April 2019

Abstract

Background
Despite significant growth of the global skin care market, many plastic surgeons do not offer skin care products through their aesthetic practice. However, skin care products represent a significant potential revenue stream for plastic surgeons, not only by generating revenue from product sales but by improving patient retention over time and, in turn, generating additional surgical and nonsurgical revenue.

Objectives
The purpose of this study was to determine the financial implications that skin care sales can have for an aesthetic surgery practice. Our hypothesis was that patients making skin care purchases would generate higher non-skin care revenue than patients not purchasing skin care products.

Methods
A retrospective chart review was performed of all purchases made within a single aesthetic surgery practice during a 6-year period (2012-2017). Pre-tax revenue ($CAD) from each category was recorded for any patient who made a purchase during the study period.

Results
A total 3785 patients purchased skin care products, 5088 patients purchased nonsurgical treatments, and 3504 patients underwent surgery. Average patient spending was $720.73 (skin care), $1272.63 (nonsurgical), and $10,048.34 (surgery), respectively. Overall, patients who purchased skin care generated more revenue from the purchases of nonsurgical treatments and surgery than patients who did not purchase skin care products.

Conclusions
Skin care sales not only generate revenue, but over time these patients spend more on nonsurgical and surgical treatments than patients who do not purchase skin care. Skin care is an important adjuvant to nonsurgical and surgical treatments that should be considered by all aesthetic surgeons.
Gone with the rain: negative effects of rainfall on male reproductive success in a nest-building arachnid
Authors: Rojas Andrés , Solano-Brenes Diego , Muniz Danilo G , Machado Glauco 
Published: April 2019

AbstractIn nest-building species, offspring survival and reproductive success of parental individuals are strongly influenced by nest quality. Thus, quantifying the influence of abiotic conditions on nest integrity is important to predict the effects of weather variability on the fitness of parental individuals. Here, we investigated how rainfall affects nest integrity and how nest integrity influences males’ attractiveness and nest tenure. Our study species was the harvestman Quindina limbata, in which males build mud nests on fallen logs and protect the eggs against predators and fungi. Our data set comprises 12 months of regular inspections of 149 nests in a Costa Rican rainforest. We found that almost 50% of the nests were destroyed by rainfall. The drag force caused by rainfall running on the fallen log surface negatively affected nest integrity. Fungi cover on nests was influenced by an interaction between rainfall and nest position on the fallen log. Irrespective of their body size, males in nests with high integrity received more eggs than males in nests with low integrity. Fungi cover did not influence the number of eggs received by the males. Finally, nest integrity and fungi cover did not affect nest tenure, but males that did not receive eggs for a long time tended to abandon their nests. Considering that intense rainfall occurs all year long in tropical forests, males should build their nests in protected sites that preserve nest structure. Protected sites may keep nest structure better preserved, improve offspring survival, attract more females, and increase males’ reproductive success.