bluuebunny/crossref_metadata_2025_split huggingface dataset:
Küçük hücreli dışı akciğer karsinomlarında tümör ilişkili makrofajların tümör progresyonundaki rolü
Authors: TEPEOĞLU Merih , TAŞTEPE F.zeynep , ÖZDEMİR B.handan 
Published: April 2018

Amaç: Akciğer kanseri tüm dünyada kanserden ölümlerin en sık sebebidir. Küçük
hücreli dışı akciğer karsinomları (KHDAK) da en sık görülen akciğer kanser
tipidir. Bu çalışmada küçük hücreli dışı akciğer karsinomlarında, tümör
ilişkili makrofajların (TAM) tümör progresyonu ve metastaz üzerindeki etkileri
araştırıldı.

Gereç ve
Yöntem: Ocak 2011 ile Mayıs 2016 tarihleri arasında
Başkent Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalında KHDAK tanısı alan
80 olgu çalışmaya dahil edildi. Olguların klinik takip bulguları kaydedildi ve
tüm olgulara immünhistokimyasal olarak CD 68 antikoru uygulandı.

Bulgular: Olguların 36’sı (%45) skuamöz hücreli karsinom (SHK), 36’sı (%45)
adenokarsinom, 6’sı (%7.5) büyük hücreli karsinom ve 2’si de (%%2.5)
adenoskuamöz karsinom idi. Yapılan immünhistokimyasal çalışma sonucunda, 28
olgunun (%35) tümör dokusunda 1+, 21 olgunun (%26.3) tümör dokusunda 2+ ve 31
olgunun (%38.8) tümör dokusunda ise 3+ TAM yoğunluğu izlendi. Evre 1 olan 32
hastanın yalnızca 1 tanesi (%3.1) 3+ TAM yoğunluğuna sahipken, evre 2 olan 32
hastanın 17’sinde (%53.1) ve evre 3+4 olan 16 hastanın ise 13’ünde (%81.3) 3+
TAM yoğunluğu saptandı. TAM yoğunluğu 1+ olan hastaların ortalama yaşam ömrü 39.7±17.4
ay iken, TAM yoğunluğu 2+ olan hastaların 36.6±17.1 ay ve TAM yoğunluğu 3+ olan
hastaların ise 27.3±18.4 aydı (p&lt;0.05).

Sonuç: Bu çalışmada, patolojik T evresi ve TNM evresi yüksek olan KHDAK’da TAM
sayısının daha yüksek olduğu görüldü ve yüksek TAM sayısı olan hastaların
ortalama sağkalım süresinin de, düşük TAM sayısı olan hastaların sağkalım
süresinden kısa olduğu saptandı.
Papel de la sensibilización central en la cronificación del dolor postquirúrgico
Authors: Sanisidro Torre Roberto 
Published: April 2018

El dolor crónico posquirúrgico (DCPQ) es un cuadro clínico que dura al menos tres meses tras una intervención quirúrgica, donde adicionalmente se observan síntomas dolorosos neuropáticos. El prerrequisito para el desarrollo de DCPQ es una lesión a los nervios principales que discurren por el lecho quirúrgico. En un estado basal, un estímulo nocivo despolariza una neurona sensitiva (nociceptor); ese nociceptor, en la médula espinal transmite la señal a una neurona espinal que envía la señal al tálamo; desde el tálamo se estimulan distintos centros cerebrales; la corteza prefrontal integra toda la información y el paciente siente dolor. En ocasiones, no existe relación entre el estímulo doloroso y la respuesta que origina en el SNC: es entonces cuando se produce una importantísima amplificación de la señal nociceptiva, y a este fenómeno se le conoce como sensibilización neuronal o neuropatía, de forma que la información transmitida al cerebro origina una reacción dolorosa desproporcionada. Este desarreglo se produce tanto a nivel periférico (sensibilización periférica) como a nivel central (sensibilización central). Existe una nueva línea de abordaje, que evalúa los factores de riesgo: como el dolor postoperatorio agudo severo, las técnicas quirúrgicas mínimamente invasivas y las estrategias analgésicas preventivas multimodales; como factores sobre los que podemos ser capaces de influir en aras de evitar el desarrollo de esta sensibilización que favorece la cronificación del dolor.
PENGARUH SARANA PRASARANA AKADEMIK, KUALITAS MENGAJAR DOSEN, ATMOSFER AKADEMIK, DAN MOTIVASI BELAJAR TERHADAP PRESTASI BELAJAR MAHASISWA
Authors: Arafah Khairudin 
Published: April 2018

This research aims to know the effect of acedemic infrastruktur for lecturer qualities in teaching, Academic infrastruktur for academic atmosphere, academic infrastruktur for student motivation in learning, lecturer quality in teaching for academic atmosphere, lecturer quality in teaching for student achievement in learning, and motivation in study for student achievement in learning. For achieving those aims, we observed 51 students which is choose by simple random. The results of this research showed that academic infrastruktur give positif impact for lecturer quality in teaching
Abstrak
Penelitian ini bertujuan untuk mengtahui pengaruh sarana prasarana akademik terhadap kualitas mengajar dosen, sarana prasarana akademik terhadap atmosfer akademik, sarana prasarana akademik terhadap motivasi belajar mahasiswa, atmosfir akademik terhadap motivasi belajar mahasiswa, kualitas mengajar dosen terhadap atmosfer akademik, kualitas mengajar dosen terha-dap prestasi belajar mahasiswa, dan motivasi belajar terhadap prestasi belajar mahasiswa. Untuk mencapai tujuan tersebut, telah dilakukan survey kepada 51 orang mahasiswa yang diambil se-cara acak sederhana. Hasil penelitian menunjukkan bahwa sarana prasarana akademik berpengaruh langsung positif terhadap kualitas mengajar dosen
KEARIFAN LOKAL KABANTI UNTUK MASYARAKAT BUTON (PENELITIAN ANALISIS KONTEN)
Authors: Sahlan Sahlan 
Published: April 2018

The aims of this research is to describe the local wisdom in Kabanti for people of Buton. In order to describe the matter, the researcher Ude through five informan and three Kabanties written by Haji Abdulu Ganiyyu as the source of data. The data were collected using observation, interview, and documentation techniques. The data validity were varified using triangulation method through theoretical and logical information. The data were analyzed using content analysis, hermeneutic and semiotic. The research conclude the general illustration of kabanti looks like Poe that apart of them be sang by the people of Buton. Kabanti containing the values of local wisdom in for aspects. The first aspect, the live vision of the people of Buton is based on religous value namenly the relation of human being with Allah SWT, the relation of human being with human being, and the relation of human being with the nature. The Second, norma or law aspect of the people of Buton have values; Obey to regulation, fair attitude, to take the honorable to the human being and always Control themselves. The Third aspect, social aspect of the people of Buton have the values; Love, Care, take the honorable Beach other and respect. The Fourth, the culture aspect of the people of Buton have the values, sincerity, tolerance, togetherness all. Therefore, local wisdom in kabanto of Buton society has implications for the insight Development and student implementation in learning Education character.
Abstrak
Tujuan penelitian ini adalah untuk mendeskripsikan kearifan lokal Kabanti untuk masyarakat Buton. Untuk mendeskripsikan materi ini, peneliti Ude melalui 5 informan dan 3 orang penulis Kabanti oleh Haji ABdulu Ganiyyu sebagai sumber data. Data dikumpulkan menggunakan observasi, wawancara, dan teknik dokumentasi. data validitas menggunakan metode triangulasi melalui teori dan informasi logis. Data dianalisis menggunakan analisis konten, hermeneutic and semiotic. Peneliti menyimpulkan ilustrasi umum dari Kabanti seperti puisi bahwa bagian mereka adalah lagu masyarakat Buton. Kabanti yang berisi nilai-nilai kearifan lokal dalam beberapa aspek. Aspek pertama, visi kehidupan masyarakat Buton didasarkan nilai religius yang mengutamakan hubungan manusia dengan Allah SWT, hubungan manusia dengan manusia, dan hubungan manusia dengan alam. Kedua, norma atau aspek hukum masyarakat Buton memiliki nilai yaitu: patuh pada peraturan, sikap adil, menghormati manusia dan selalu mengkontrol diri mereka. Aspek ketiga, aspek sosial masyarakat Buton memiliki beberapa nilai yaitu: Cinta, peduli dan saling menghormati. Keempat, aspek budaya masyarakat Buton memiliki beberapa nilai, kasih sayang, toleransi, dan kebersamaan. Oleh karena itu kearifan lokal Kabanti masyarakat Buton memiliki implikasi untuk perkembangan pengetahuan dan penerapan pendidikan karakter untuk siswa
STUDI SIFAT ELEKTROKIMIA SEL BATERAI SEKUNDER POUCHCELL LITHIUM ION LIFEPO4/GRAPHITE APLIKASI DAYA TINGGI
Authors: Subhan Achmad , Prihandoko Bambang 
Published: April 2018

Abstrak
Telah dilakukan pembuatan lembaran katoda dari serbuk LiFePO4 komersial dan anoda dari serbuk Graphite. Lembaran difabrikasi membentuk sel penuh baterai dengan tipe sampel uji berbentuk Pouchcell. Konfigurasi sel adalah LiFePO4//LiPF6//graphite, LiPF6 digunakan sebagai elektrolit cair. Karakterisasi sel dilakukan meliputi uji cyclic voltrametry, charge discharge dan EIS (electrochemical Impedance Spectroscopy. Nilai yg dihasilkan adalah kapasitas mencapai sekitar 80 mAh/gr, dengan tegangan Voc stabil pada nilai 3.28 V. Nilai discharge capacity yang bisa diambil hingga 5C lebih dari 40%, dengan life cycle pada 50 siklus kehilangan kapasitas hanya kurang dari 5%.
Kata-kata kunci: pouchcell, cyclic voltametry, electrochemical impedance spectroscopy, baterai high power.
Abstract
In this work, have been fabricated cathode electrode from LiFePO4 powder and anode from commercial Graphite powder. Full cell batteries fabricated in Pouchcell shaped test samples. Lithium ion cell configuration are LiFePO4 // LiPF6 // graphite, 1 M LiPF6 in EC/DEC is used as the liquid electrolyte. Cell batteries Perfomance characterized by some tests conducted on the cyclic voltrametry, charge-discharge and EIS (electrochemical impedance spectroscopy. The result value are the capacity reached approximately 80 mAh / g, with the voltage Voc perfectly stable at 3.28 V. The discharged capacity can be taken up to 5C almost over 40% , with after 50 cycles for life cycle test the capacity loss is retain still 95% at 0.33C.
Keywords: pouchcell, cyclic voltametry, electrochemical impedance spectroscopy, high power battery.
KORELASI POLARISASI MAGNET Z/H UNTUK IDENTIFIKASI PREKURSOR GEMPA DI SEKITAR PELABUHAN RATU
Authors: Ahyar Asep Saepul , Sunardi Bambang 
Published: April 2018

Abstrak
Efek seismo-elektromagnetik yang berlangsung dalam rentang frekuensi luas yang mendahului gempa telah banyak dilaporkan dalam beberapa penelitian sebelumnya. Efek tersebut diharapkan dapat dimanfaatkan dalam mitigasi bencana gempa. Penelitian ini membahas penerapan metode korelasi polarisasi magnet komponen Z/H untuk mengidentifikasi prekursor gempa di sekitar Pelabuhan Ratu. Data yang dipergunakan adalah data magnet tiga komponen selama 31 hari sebelum kejadian gempa. Identifikasi anomali geomagnet dilakukan dengan menerapkan metode korelasi polarisasi magnet Z/H untuk menghitung rasio Simpangan koefisien korelasi (Skk) dengan Deviasi standar simpangan koefisien korelasi (Dskk). Ambang batas anomali adalah -1. Nilai Skk/Dskk < -1 mengindikasikan adanya anomali geomagnet. Kemunculan badai magnetik yang mempengaruhi anomali geomagnet dievaluasi menggunakan Disturbance storm time index (indeks Dst). Hasil penerapan metode korelasi polarisasi magnet Z/H pada lima kasus gempa di sekitar Pelabuhan Ratu dari Januari – Maret 2017 dengan magnitudo M > 4 dan memenuhi radius zona manisfestasi prekursor menunjukkan kemunculan anomali geomagnet yang dikategorikan sebagai prekursor gempa. Kemunculan anomali geomagnet berkisar antara 16 – 2 hari sebelum gempa terjadi.
Kata-kata kunci: korelasi, geomagnet, prekursor gempa, Pelabuhan Ratu.
Abstract
Seismo-electromagnetic effects occurring in wide frequency range that preceded earthquake have been widely reported in several previous studies. The effect is expected to be utilized in earthquake disaster mitigation. This study discusses application of magnetic polarization correlation method of Z / H component to identify earthquake precursors around Pelabuhan Ratu. Data used are three components magnet data for 31 days before earthquake events. Identification of magnetic anomaly was done by applying the magnetic polarization Z / H method to calculate correlation coefficient ratio (Skk) with standard deviation of correlation coefficient deviation (Dskk). The anomaly threshold is -1. Less than -1 of Skk / Dskk values indicate geomagnetic anomaly. The emergence of geomagnetic storms that affect geomagnetic anomalies is evaluated using the Disturbance storm time index (Dst index). The result of application of Z / H magnet polarization correlation method in five earthquake cases around Pelabuhan Ratu from January to March 2017 with magnitude M > 4 and meeting precursor manifestation radius zone showed the occurrence of geomagnetic anomalies categorized as earthquake precursors. The appearance of geomagnetic anomalies ranged from 16 to 2 days before earthquakes occurred.
Keywords: correlation, geomagnetic, earthquake precursor, Pelabuhan Ratu.
ANALISIS KOMPLEKSITAS STRUKTUR PORI PADA SAMPEL DIGITAL MEDIUM BERPORI
Authors: Fawziah Ulpa Zein , Rochmatulloh Aceng Kurnia , Sumaryono Rizki Fahmi , Feranie Selly , Latief Fourier Dzar Eljabbar 
Published: April 2018

Abstrak
Kompleksitas struktur pori terhubung pada sampel digital medium berpori 2D telah dianalisis menggunakan parameter tortuositas. Jalur pori terhubung dilacak dengan menggunakan Simple Neurite Tracer. Metode pelacakan dan perhitungan tortuositas tersebut diujikan pada lima model sederhana yang menunjukan perbedaan tingkat kompleksitas yang signifikan. Metode analisis kompleksitas tersebut kemudian diterapkan pada sampel medium berpori berupa citra digital batuan berukuran 560 × 393 piksel, dan tanah berukuran 560 × 475 piksel. Citra digital sampel tanah dan batuan yang dianalisis berupa irisan 2D pada bidang z-y (sagittal) yang diambil dari sampel 3D hasil pemindaian menggunakan -CT Scanner SkyScan 1173. Pelacakan jalur pori terhubung pada sampel model maupun sampel digital 2D batuan dan tanah yang menggunakan Simple Neurite Tracer menghasilkan koordinat jalur pori terhubung yang kemudian digunakan untuk menghitung nilai tortuositas. Tortuositas dihitung dengan menggunakan definisi rasio antara jumlah total sudut keberlikuan jalur terhadap jarak antara dua sisi sampel yang saling berhadapan. Untuk 5 sampel model yang menunjukkan kompleksitas yang berbeda, diperoleh bahwa semakin kompleks struktur pori tersebut, maka semakin besar nilai tortuositasnya. Untuk analisis pada sampel digital batuan, nilai tortuositasnya yaitu 0,0392 sedangkan pada sampel tanah didapat nilai tortuositas sebesar 0,0431.
Kata-kata kunci: simple neurite tracer, tortuositas, kompleksitas, medium berpori
Abstract
The complexity of the connected pore structure of 2D porous digital media samples has been analyzed using tortuosity parameter. Connected pore was traced using the Simple Neurite Tracer. The tracing method and the tortuosity calculation were tested on five simple models showing significant differences in complexity levels. The complexity analysis method was then applied on digital image of a rock sample with the size of 560 × 393 pixels, and a soil sample with the size of 560 × 475 pixels. Digital images of the rock and soil samples were analyzed on the 2D slices in the zy (sagittal) plane which were obtained from the scanned 3D samples using the µ-CT SkyScan 1173 Scanner. Connected pore tracing for both the 2D models as well as the rock and soil samples was done using the Simple Neurite Tracer which produce the coordinate of the connected pore path which is then used to calculate the value of tortuosity. Tortuosity is calculated by using the definition of the ratio between the sum of the curvaceous angles of the connected pore path to the distance between two facing sides of the sample. For 5 sample models with distinctive complexity, it was found that the more complex the pore structure, the greater the tortuosity value. For analysis on digital samples of rocks, the tortuosity is 0.0392 whereas in the soil sample, the tortuosity is 0.0431.
Keywords: simple neurite tracer, tortuosity, complexity, porous medium.
EDDY CURRENT SENSOR BERBASIS FLAT COIL FR4 UNTUK MENENTUKAN KETEBALAN PELAT LOGAM NON MAGNETIK AL
Authors: Emrinaldi Tengku , Salomo Salomo , Hamzah Yanuar , Iwantono Iwantono , Umar Lazuardi 
Published: April 2018

Abstrak
Sensor arus eddy (eddy current) digunakan untuk pengukuran ketebalan logam khususnya logam non magnetik seperti alumunium. Penelitian ini telah mengembangkan sensor eddy current berbahan PCB (printed circuit board) jenis FR4 yang memiliki ketebalan lapisan tembaga 35micron. Prototipe yang dihasilkan mempergunakan koil sensor dengan jumlah gulungan (n) 30 lilitan, diameter (Æ) 30mm, lebar dan jarak antar koil, (dkoil) 0,254mm dan tahanan (Rkoil) sebesar 4,26Ω. Respon sensor ketebalan pelat logam terhadap bahan uji dievaluasi dengan memberikan eksitasi frekuensi tunggal 700Khz, 1MHz dan 1.33MHz. Rangkaian ketebalan pelat telah mempergunakan rangkaian pengunci fasa (phase locked loop) dan mampu mengukur variasi ketebalan mulai 0,2 mm sampai 2 mm, sementara jarak antara sensor dengan logam uji dijaga konstan 2 mm. Hasil pengukuran memberikan respon kurva U(t) dalam hubungan
Kata-kata kunci:sensor eddy current, PCB FR4, material non magnetik, ketebalan logam, rangkaian phase locked loop
Abstract
Eddy current sensor is used to measure the thickness of metals, especially non-magnetic metals such as aluminum. This research has developed eddy current sensor made from PCB (printed circuit board) type FR4 which has 35micron copper layer thickness. The developed prototype uses a designed coil sensor with the number of winding (n) 30 turn, diameter () 30mm, width and distance between coils, (dkoil) 0.254 mm and coil resistance (Rkoil) of 4.26 Ω. The sensor response to the test material was evaluated by giving a single frequency excitation of 700 Khz, 1 MHz and 1.33 MHz. The plate thickness electronics has used a phase locked loop circuit and is capable to measure the thickness variations from 0.2 mm up to 2 mm, while the distance between the sensor coil and the test object was kept constant at 2 mm. The measurement results give the U (t) curve response in the exponential relationship.
Keywords: eddy current sensor, PCB FR4, nonmagnetic material, thickness, phase locked loop circuit
Training-Image Assisted History Matching of Complex Multiple-Point Statistical Facies Models: A Pattern-Based Approach
Authors: Khaninezhad M. , Golmohammadi A. , Jafarpour B. 
Published: April 2018

Abstract
Traditional geostatistical methods that rely on two-point statistics (i.e., variogram models) to describe the spatial variability in rock properties are not appropriate for representing the spatial continuity patterns associated with complex geologic objects (e.g., curvilinear fluvial patterns and turbidite systems). Modern geostatistical techniques are developed to simulate multiple-point statistical (MPS) patterns from a training image (TI), as a conceptual model of geologic continuity, to generate model realizations with complex geologic connectivity. A major difficulty in using MPS methods is related to conditioning the simulation results on nonlinear dynamic production data. We develop a pattern-based model calibration approach for conditioning MPS-based facies models on nonlinear flow data. The formulation begins with defining a minimization problem in which the mismatch between predicted and observed production data is minimized. Since facies distributions are discrete variables, we use a parameterization method to transform them into a small number of continuous parameters that can be updated using gradient-based minimization. For this purpose, k-SVD sparse dictionary learning is adopted to approximate the connectivity patterns in the distribution of facies models. Because of the approximation involved in the k-SVD parameterization, an additional step is introduced, after each iteration, to map the resulting continuous models to the TI. To implement the mapping, a local search template is used to scan the TI to find local discrete patterns with smallest distances from the corresponding local patterns in the continuous solution. This process is repeated for all the grid cells in the continuous solution and the resulting local patterns are stored. To estimate the facies type in each grid cell, the collected patterns that intersect with any given cell are used to find the facies type with the highest frequency and assign it to that cell. Once the discrete solution is identified, it is passed to the continuous minimization problem to serve as a regularization term, for the next update iteration. The process is repeated until the discrete solution provides an acceptable match to the data. Numerical experiments are presented to evaluate the performance of the proposed approach for facies calibration in complex fluvial systems. The results suggest that the developed method presents a promising pattern-based approach for integration of production data into MPS-based facies models.
Surviving the New Oil Price Landscape: A Case Study Breaking Down Liquid-Rich Basins in the Rockies
Authors: Srinivasan Karthik , Krishnamurthy Jayanth , Borchardt Shannon 
Published: April 2018

Abstract
The oil and gas production landscape in North America has seen a paradigm shift since the collapse in oil prices in 2014. Although prices remain challenging, several operators have managed to sustain the relatively long period of low margins through some aggressive approaches. This paper inspects changes in operating strategies and field development plans across all oil-rich basins in the US Rocky Mountain fields and how operators have used a combination of low oilfield service prices, high-graded well locations, and incremental fluid/proppant volumes to increase production.
The paper investigates the transformation in operating philosophies since 2014 in four oil-rich basins in the Rocky Mountain region—Williston, Denver-Julesburg (DJ), Uinta, and Powder River. The Bakken formation in the Williston basin represents one of the best-quality rocks in all of North America. However, high oil-price differentials and well costs have made it difficult for drilling to remain profitable. The core of the DJ basin (Wattenberg) has one of the lowest break-even prices in the region, and rig count continues to increase as operators start seeing signs of recovery in the market. The Uinta basin, although relatively small in size, has shown tremendous return potential in the form of multiple stacked pays and promising production results. The Powder River basin poses one of the toughest operational environments in the region owing to wildlife stipulations, harsh weather, and deeper targets.
High-graded well locations in the Bakken are limited to few fields, which limits the scope of expansion in the current oil price environment. The DJ basin is challenged with high-density well spacing; estimated ultimate recovery (EUR) per drilling spacing unit (DSU) continues to increase, but EUR per well has gone down by as much as 60%. In the Uinta basin, formations never known to be continuous in the Green River group have shown significant return potential. The Powder River basin has recently attracted large investments from major independent operators as they tackle drilling challenges associated with abrasive rocks and testing optimum lateral landing points.
Case studies show how operating strategies have changed with changes in oil prices. The Bakken and DJ basins are relatively mature, and as drilled-but-uncompleted (DUC) inventory continues to increase, depletion from existing wells and interference between fractures is impacting production from new wells. The Powder River basin is still in the exploratory phase, and operators are still working on reducing well-costs, optimizing fracturing-fluid/proppant volumes, and examining productivity of other target rocks. The Uinta basin is in the early phases of expansion, with many of the fields still being explored for scalability. Changes in production maps and completion trends provide a comprehensive understanding of how these variables have impacted oil output from the region since 2012.