bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hemophagocytic Lymphohistiocytosis: Prevalence, Risk Factors, Outcome, and Outcome-related Factors in Adult Idiopathic Inflammatory Myopathies
Authors: Liang Junyu , Xu Danyi , Sun Chuanyin , Chen Weiqian , Cao Heng , Lin Jin 
Published: October 2019

Objective.To clarify the prevalence, risk factors, outcome, and outcome-related factors of hemophagocytic lymphohistiocytosis (HLH) in patients with dermatomyositis (DM), polymyositis (PM), or clinically amyopathic dermatomyositis (CADM).Methods.Data of patients with DM, PM, or CADM who were admitted to the First Affiliated Hospital of Zhejiang University from February 2011 to February 2019 were retrospectively collected. Patients diagnosed with HLH constituted the case group. A 1:4 case-control study was performed to identify risk factors for HLH in patients with DM, PM, or CADM through comparison, univariate, and multivariate logistic regression analysis. Intragroup comparison was made among patients with HLH to identify factors influencing unfavorable short-term outcome.Results.HLH was a rare (4.2%) but fatal (77.8%) complication in patients with DM, PM, or CADM. The retrospective case-control study revealed that higher on-admission disease activity (p = 0.008), acute exacerbation of interstitial lung disease (AE-ILD, p = 0.002), and infection (p = 0.002) were risk factors for complication of HLH in patients with DM, PM, or CADM. The following intragroup comparison showed that higher on-admission disease activity (p = 0.035) and diagnosis of CADM (p = 0.039) might influence the short-term outcome of patients with HLH. However, no risk factor was identified after false discovery rate correction.Conclusion.In this study, secondary HLH was a fatal complication, with higher on-admission disease activity, AE-ILD, and infection working as risk factors. The underlying role of infection and autoimmune abnormality in HLH in connective tissue disease was subsequently noted. Clinical factors influencing the short-term outcome of patients with secondary HLH require further study.
Prevalence of Psoriatic Arthritis Patients Achieving Minimal Disease Activity in Real-world Studies and Randomized Clinical Trials: Systematic Review with Metaanalysis
Authors: Zardin-Moraes Mariele , da Silva André Luis Ferreira Azeredo , Saldanha Carla , Kohem Charles Lubianca , Coates Laura C. , Henrique Lilian Rodrigues , Palominos Penélope Esther , Chakr Rafael Mendonça da Silva 
Published: October 2019

Objective.To estimate the frequency of patients with psoriatic arthritis (PsA) achieving minimal disease activity (MDA) status in real-world studies and randomized controlled trials (RCT).Methods.A systematic literature search for 2009–2017 was performed in PubMed, Embase, Cochrane Library, and LILACS. Study selection and data extraction were performed by 2 independent researchers. Random-effects single-arm metaanalyses were performed and heterogeneity was assessed using I2.Results.A total of 405 records were identified and 45 studies were analyzed: 39 (86.7%) observational studies and 6 (13.3%) RCT; they included 12,469 patients. The overall prevalence of MDA in cross-sectional studies was 35% (95% CI 30%–41%, I2 = 94%), varying from 17% (95% CI 7%–34%) in patients taking synthetic disease-modifying antirheumatic drugs (DMARD) to 57% (95% CI 41%–71%) in those taking biological DMARD. Prevalence of MDA in cohort studies increased with longer followup time, ranging from 25% (95% CI 15%–40%) with 3- to 4-month followup to 42% (95% CI 38%–45%) with > 24-month followup. Patients with PsA receiving biological DMARD in a real-world context and RCT had similar prevalence of MDA at 6-month followup: 30% (95% CI 21%–41%, I2 = 85%) versus 32% (95% CI 26%–39%, I2 = 79%), respectively.Conclusion.Patients with PsA included in real-world studies had similar prevalence of MDA compared to those in controlled clinical trials. This finding suggests that MDA is a useful treatment target for PsA in the real-world setting.
Health care professionals “coming out”: a critical dialogue
Authors: Coveney John , Thompson Lee 
Published: October 2019

S’intéresser à l’optimisation de soi dans le cadre professionnel permet de faire émerger des perspectives critiques en termes de formation, de pratique et de politique. Dans le domaine de la santé, il a ainsi été souligné que l’autogestion, la responsabilité individuelle et l’optimisation de soi étaient devenues des objectifs pour la prévention, le traitement et le care . En revanche, les manières dont les professionnels de santé s’optimisent eux-mêmes ont été moins étudiées. L’utilisation de la méthode de conversation « à tour de rôle » nous permet ici d’opérer un véritable coming out qui mêle, à travers le récit de nos parcours respectifs, nos expériences passées de professionnels de santé où nous étions confrontés quotidiennement à l’optimisation de soi, et nos réflexions actuelles d’universitaires sur l’injonction à la responsabilité individuelle.
Un point aveugle historiographique ? La cour d’Espagne au XVIII e siècle : problématiques et perspectives récentes
Authors: Vázquez Gestal Pablo 
Published: October 2019

Les études sur la cour du roi d’Espagne à l’époque moderne se sont fortement développées dans les deux dernières décennies, mais l’intérêt des chercheurs s’est concentré principalement sur les xvi e et xvii e siècles, beaucoup moins sur le xviii e siècle. Cet article analyse cette tendance historiographique et ses limites en abordant dans une première partie les principaux axes thématiques à travers lesquels ce sujet a été étudié, pour expliquer ensuite ses caractéristiques épistémologiques et les effets de sa présence ou de son absence actuelle sur l’interprétation du xviii e siècle espagnol.
Expériences en milieu scolaire : le point de vue des auteurs
Authors: Brière-Haquet Alice 
Published: October 2019

La Charte des auteurs et illustrateurs jeunesse – association professionnelle rassemblant quelque 1200 créateurs – s’est construite sur la volonté d’accompagner les rencontres en milieu scolaire, imposant au fil des années un ensemble de normes aujourd’hui largement reconnues. Elle proposait début 2017 une enquête auprès de ses adhérents afin de faire le point sur les pratiques et enjeux de ces rencontres. Les questions s’organisaient autour de quatre axes : l’importance économique des rencontres pour les auteurs, le retour sur leurs expériences, la place accordée au numérique et les difficultés administratives éventuellement rencontrées. Cent vingt-huit auteurs et illustrateurs ont répondu à son appel. Leurs réponses, présentées et commentées dans cet article, permettent de poser les jalons d’une rencontre réussie, mais soulignent également son irréductible singularité.
Un consensus paradoxal
Authors: Cortinas Muñoz Joan , Poupeau Franck , Razafimahefa Lala 
Published: October 2019

Résumé Cet article a pour objectif d’expliquer l’émergence paradoxale de politiques de water conservation (recyclage des eaux de pluie, stockage destiné à reconstituer les nappes souterraines, etc.) dans l’Ouest étasunien, où le développement économique constitue pourtant une priorité politique. Loin d’être un simple effet de la sécheresse prolongée qui touche l’Arizona, ces politiques hydriques renvoient à des logiques sociales et institutionnelles spécifiques que cet article entend analyser. Il défend l’idée selon laquelle les « protagonistes de l’eau » se coalisent autour d’instruments d’action communs. Cette « coalition programmatique instrumentale » ne se réduit pas à une simple adhésion normative à des objectifs politiques : elle renvoie aux caractéristiques sociales des protagonistes. L’accord pratique sur des instruments d’action permet ainsi une conciliation d’intérêts sensiblement différents. Des compétences techniques communes ont permis l’écologisation des politiques hydriques, initiées par les autorités locales du Pima County jusqu’à l’ensemble des professionnels de l’eau.
Debriefing and Palliative Care Simulation
Authors: Nunes Stephanie , Harder Nicole 
Published: October 2019

Background:
Palliative simulation is a beneficial bridge between theory and practice; however, it can be emotionally laden. Often overlooked during a debrief session of a palliative simulation is ensuring that participants have the skills to process the feelings they may experience.

Method:
The purpose of this mixed-methods concurrent triangulation study was to understand the perceived value and usefulness of debriefing in palliative simulation process feelings and emotions.

Results:
The simulation modality affects the intensity of feelings. A debriefer who is skilled in both debriefing simulation and coping with emotionally stressful situations allowed students to feel prepared to cope with their own feelings about palliative care. Having other students talk about their feelings in debriefing helped students to normalize their feelings.

Conclusion:

The debriefing in palliative-based simulations requires additional considerations regarding modality and the skill set of the debriefer to adequately assist students to process feelings and emotions.

[
J Nurs Educ.
2019;58(10):569–576.]
Importance of and Satisfaction With Characteristics of Mentoring Among Nursing Faculty
Authors: Gentry Jacklyn , Johnson Kelly Vowell 
Published: October 2019

Background:
Mentoring programs have the potential to influence the nursing faculty shortage by increasing job satisfaction while providing novice faculty with support during the transition from clinical practice to nursing faculty. This study aimed to determine nursing faculty perceptions of the importance of mentor characteristics and a mentoring relationship, and the level of satisfaction with mentoring within the nursing education profession.

Method:
A cross-sectional design offered an online survey that was completed by 61 nursing faculty teaching in baccalaureate programs or higher in a midwestern state.

Results:
The results did not demonstrate a statistically significant relationship among survey items; however, mentoring characteristics that demonstrated both high importance and high satisfaction were trust and support.

Conclusion:

Deeper insight into the characteristics of mentoring that are of importance and produce satisfaction is essential to the development of formal mentoring programs to make a positive, lasting effect on the nursing education profession.

[
J Nurs Educ.
2019;58(10):595–598.]
Un royaume à cheval sur les Pyrénées : Pedro de Lizarazu et l’hispanisation d’une lignée
Authors: Zabalza-Seguín Ana 
Published: October 2019

Depuis le xiie siècle, la Basse-Navarre est associée au
Royaume de Navarre et le sera jusqu’en 1527. Après la Conquête et son
incorporation à la Castille (1512-1515), elle sera abandonnée. Pendant
quatre siècles, il faut souligner la forte présence – en nombre et
importance – de lignées originaires de cette région à la cour de
Navarre. Les plus remarquables parviendront à s’apparenter à la
famille royale, participant dans le gouvernement et à la défense du
territoire. Leur vie sera rattachée à la défense de la frontière et
aux missions diplomatiques dans différents royaumes européens. Cet
article porte sur une de ces lignées, les Lizarazu. En divisant la
cour en deux bandes irréconciliables (1451), leur destin sera rattaché
à celui du prince Carlos de Viana. Leur défaite ira de pair avec l’hispanisation de la lignée et
l’abandon de leurs bases au nord des Pyrénées.
Construire une identité professionnelle malgré des conditions de travail difficiles : les apprenti-e-s en commerce de détail en Suisse
Authors: Caprani Isabelle , Duemmler Kerstin , Felder Alexandra 
Published: October 2019

Cette contribution porte sur l’analyse des conditions de travail auxquelles les apprenti‐e‐s en commerce de détail sont soumis‐es au cours de leur formation. Nous proposons d’étudier - par l’intermédiaire d’une enquête qualitative basée sur des observations, des entretiens et des discussions de groupe - comment les apprenti‐e‐s vivent leur formation et quel rôle jouent les conditions de travail dans leur identification au métier. Quatre dimensions expérimentées par les apprenti-e-s ont émergé des analyses : l’intensité du travail, la disponibilité temporelle couplée à l’insécurité socio-économique, les rapports sociaux en entreprise et le rapport à la clientèle. La question de l’autonomie et des marges de manœuvre est traitée de manière transversale, car elle contribue à atténuer ou amplifier les autres conditions.
L’intérêt de la DVP pour (re)donner du sens aux apprentissages
Authors: Blond-Rzewuski Olivier 
Published: October 2019

La lutte contre les inégalités scolaires et sociales nécessite de repenser le rapport aux savoirs. La philosophie pour enfants peut être envisagée comme un levier pour réfléchir au sens donné aux apprentissages en développant leur « posture d’apprenant ». Cet article témoigne d’une pratique enseignante sur plusieurs années, à l’école élémentaire, en éducation prioritaire (REP+). La discussion à visée philosophique (DVP) y est mise au service des différents champs disciplinaires et se révèle vectrice de l’envie d’apprendre chez des élèves particulièrement fragiles scolairement et socialement. La philosophie est donc envisagée comme une « modalité d’apprentissage ». A travers un dispositif original, à connotation lipmannienne, il s’agit de favoriser ou de développer cette « posture d’apprenant » en s’inscrivant quelque part dans la perspective d'une pédagogie de l’étonnement ou de l’énigme. Une illustration est proposée dans le cadre de la lecture au cycle 3.
Palliation of Thirst in Intensive Care Unit Patients: Translating Research Into Practice
Authors: Leemhuis Ann , Shichishima Yuriko , Puntillo Kathleen 
Published: October 2019

Background
Thirst is prevalent among patients in intensive care units. A research-based “thirst bundle” was shown to significantly decrease thirst in these patients.

Objective
To implement a research-based thirst intervention performed by intensive care unit nurses and patients’ family members.

Methods
Nurses and family members were taught the thirst intervention through video training and project team reinforcement. The intervention was performed by nurses for 123 patients and by family members for 13 patients. Thirst was measured with a numeric rating scale of 0 to 10, a word scale of 0 to 3, or “yes/no” answers, whichever was easiest for the patient. Inferential statistics were used to assess changes in thirst scores over time. Also assessed were nurse and family member burden levels, family level of satisfaction, and patient enjoyment.

Results
Thirst scores on the numeric rating scale decreased significantly: from a mean (SD) of 7.9 (2.0) before to 3.9 (2.7) after the intervention for nurses (P &lt; .001); and from 9.2 (1.5) to 5.3 (2.6) for family members (n = 13; P = .002). Word scale scores also decreased significantly, from a median (interquartile range) of 3 (3-3) before to 2 (1-2) after the intervention for nurses (P &lt; .001). Most patients (96%) reported enjoying the procedure. Median burden levels were less than 2 on a numeric rating scale of 0 to 10.

Conclusions
The palliative “thirst bundle” significantly alleviated patients’ thirst and resulted in little caregiver burden. Further efforts are warranted to incorporate this intervention into intensive care unit practice.
Evaluation of in vitro susceptibility of fosfomycin among Enterobacteriaceae isolates from urine cultures: A study from Puducherry
Authors: Sreenivasan Srirangaraj , Kali Arunava , Pravin Charles M. V. , Kunigal Seetha 
Published: October 2019

Abstract
INTRODUCTION: The increasing drug resistance among Gram-negative uropathogens and a lack of effective oral antibiotics have limited the therapeutic options available for urinary tract infections (UTIs). This shortage of newer antibiotics has paved the way for considering the use of older antibiotics such as fosfomycin. This study aims to evaluate the in vitro susceptibility of Enterobacteriaceae isolates to fosfomycin.
MATERIALS AND METHODS: In this descriptive study conducted over a period of 6 months, we processed 1500 urine samples. The Enterobacteriaceae isolates were subjected to in vitro susceptibility testing to fosfomycin, in addition to the regularly used urinary antibiotics, by Kirby–Bauer disc-diffusion method.
RESULTS: Of 1500 urine samples processed, 582 samples yielded the growth of pathogens. Enterobacteriaceae accounted for 392 (67.3%) of the isolates. Among these isolates, lower rates of resistance were observed for imipenem (4.1%) and fosfomycin (13.3%). Relatively higher rates of resistance were observed for nitrofurantoin (35.5%) and amikacin (30.9%). Nalidixic acid, norfloxacin, gentamicin, cefotaxime, and cotrimoxazole showed a high resistance rate of 82.7%, 69.6%, 52.3%, 69.1%, and 71.4%, respectively. All antibiotics, except fosfomycin, were in routine clinical use in our hospital. The low resistance (13.3%) to fosfomycin is indicative of its utility as an excellent urinary antibiotic.
CONCLUSIONS: Uropathogenic Enterobacteriaceae isolates displayed excellent in vitro susceptibility to fosfomycin. These in vitro findings suggest the unexplored potential of fosfomycin as a superior therapeutic option for treating uncomplicated UTI.
Predictive values of neutrophil-lymphocyte ratio as an early indicator for severe acute pancreatitis in the emergency department patients
Authors: Park Hyun Sok , In Sang Guk , Yoon Hai-Jeon , Lee Woon Jeong , Woo Seon Hee , Kim Daehee 
Published: October 2019

Abstract
CONTEXT: Acute pancreatitis is an acute inflammatory disease presenting with a wide range of severity.
AIMS: We investigated the predictive values of the neutrophil-lymphocyte ratio (NLR) as an indicator for severe acute pancreatitis in the emergency department patients.
SETTINGS AND DESIGN: This retrospective study was conducted on patients with acute pancreatitis who were diagnosed in the emergency department, from January 2008 to December 2017.
SUBJECTS AND METHODS: Patients were classified into either mild-to-moderate severe group or severe group according to the Revised Atlanta Classification for Acute Pancreatitis. Clinical features and laboratory blood test parameters were considered as independent variables.
STATISTICAL ANALYSIS USED: Independent variables were analyzed using the Chi-square test and Mann–Whitney U-test to determine statistically significant differences between the two groups. Logistic regression analysis and receiver operating characteristic analysis were performed to evaluate the predictive values of significantly different variables.
RESULTS: Of the 672 patients, 52 (7.7%) were classified into the severe group. Tachycardia, fever, prevalence of liver cirrhosis and chronic alcoholism, white blood cell count, NLR, C-reactive protein (CRP), blood urea nitrogen (BUN), creatinine, aspartate transaminase, and total bilirubin were significantly higher in the severe group. Among them, NLR (adjusted odds ratio [aOR]: 1.13; 95% confidence interval [CI]: 1.081–1.181), CRP (aOR: 1.011; 95% CI: 1.004–1.017), BUN (aOR: 1.036; 95% CI: 1.004–1.069), and creatinine (aOR: 1.703; 95% CI: 1.008–2.877) were significant in the logistic regression analysis. NLR showed relatively high sensitivity (82.7%) and specificity (70%) and showed the highest area under the curve (0.821).
CONCLUSIONS: The increase in NLR was associated with severe acute pancreatitis. NLR is expected to be useful as a prognostic factor in patients with acute pancreatitis who are visiting the emergency department.
Editorial
Authors: Pérez García Elías , Martínez Arroyo Emilio José , Silva dos Santos Fabiane C. 
Published: October 2019

<p>Para este número 5 de la revista de investigación en artes visuales ANIAV, hemos seleccionado diez trabajos de indudable calidad e interés. Estos trabajos fueron recomendados por los revisores de entre los casi doscientos trabajos sometidos al sistema de doble ciego para el IV Congreso Internacional de Investigación en Artes Visuales ANIAV 2019. IMAGEN [N] VISIBLE. Se invitó a los autores seleccionados a revisar sus trabajos adecuándolas a las normas de la revista y a presentarlos en la plataforma para una nueva revisión por pares ciegos. De estos trabajos seleccionados se publicó solo un resumen en las actas del congreso y es en exclusivamente en este número 5, donde figuran corregidos y completos.</p><p> </p>
Implementing and assessing a service to demonstrate public impact of faculty research in news and policy sources
Authors: Bakker Caitlin J. , McBurney Jenny , Chew Katherine V. , Aho Melissa , Reed Del 
Published: October 2019

Background: As the need to demonstrate research impact increases, faculty are looking for new ways to show funders, departments, and institutions that their work is making a difference. While traditional metrics such as citation counts can tell one part of this story, these metrics are focused on the academic sphere and often miss the wide-ranging public impact that research can have in areas such as the news or policy documents.Case Presentation: This case report describes how one library piloted and established the Policy & News Media Impact Service, where librarians generate reports for faculty members of the University of Minnesota Academic Health Center that tracks citations of their research in governmental and organizational policies as well as local, national, and international news media. Workflows of, resources used in, and faculty feedback on the service are described.Conclusions: This Policy & News Media Impact Service pilot was successful and resulted in the establishment of a permanent service that is available to all departments in the Academic Health Center. Faculty feedback indicated that the service was valuable in demonstrating the public impact of their research. This article has been approved for the Medical Library Association’s Independent Reading Program.
Consulta a docentes del Máster de Profesorado de Secundaria sobre la alfabetización mediática e informacional (AMI). Diseño y validación del cuestionario
Authors: Santiago del Pino Michel , Permisan Cristina Goenechea , Romero Oliva Manuel Francisco 
Published: October 2019

El presente trabajo explica los procesos de validación y fiabilidad llevados a cabo para el diseño y elaboración de una consulta a través de cuestionario . Su fin ha sido conocer la opinión de los docentes en torno al estado y posibilidades de mejora de la alfabetización mediática e informacional (AMI), en el Máster Universitario en Profesorado de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanza de Idiomas (MAES), de la Universidad de Cádiz. Teniendo como referencia las fuentes documentales en torno a la materia (Ferrés, 2006; Margalef, 2010; Wilson, Grizzle, Tuazon, Akyempong & Cheung, 2011; Aguaded et al. 2011; Area, 2012; Ferrés & Piscitelli, 2012; Pérez Tornero, 2015; Fedorov & Levitskaya, 2015; Fedorov, Levitskaya & Camarero, 2016) se pudo elaborar un instrumento adecuado al contexto de aplicación. Al ser de creación propia necesitó ser validado, para lo que se sometió al juicio de expertos. Todas sus aportaciones y consejos fueron sistematizados, analizados e incorporados en la versión final del cuestionario, de forma que su validez científica asegurase el logro del propósito para el que ha sido concebido.
La versión completa del cuestionario puede consultarse en: http://educacion.uca.es/wp-content/uploads/2018/04/consulta_docentes_maes.pdf
Reflexões e reflexos a partir da perspectiva mídio-filosófica de S. Krämer
Authors: Aragão Thaís Amorim 
Published: October 2019

Este artigo apresenta alguns aspectos do pensamento de Sybille Krämer no contexto da filosofia dos meios em língua alemã, articulando-os ao trabalho de outros autores. O objetivo é revelar as particularidades da perspectiva do médium como mensageiro desenvolvida pela filósofa, ao mesmo tempo em que se joga luz sobre como outros pensadores concebem as questões levantadas – especialmente no que diz respeito a comunicação e percepção, entendimento e transmissão, transparência e opacidade, além do apriorismo dos meios.