bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unintended consequences of the potential phase-out of gamma irradiation
Authors: Chou Jacquelyn W , Skornicki Michelle , Cohen Joshua T 
Published: March 2018

The radioisotope cobalt-60 (Co-60) is important for commercial, medical, and agricultural applications. Its widespread use has meant that Co-60 can be found in less secured facilities, leading to the fear that unauthorized persons could obtain and use it to produce a “dirty bomb”. This potential security concern has led to government calls for phasing-out Co-60 and other radiation sources, despite ongoing safety and security regulations for handling, transport and use of radioactive sealed sources. This paper explores potential implications of phasing out radioisotopic technologies, including unintended safety and cost consequences for healthcare and food in the US and globally. The use of Co-60 for healthcare and agricultural applications is well-documented. Co-60 is used to sterilize single-use medical devices, tissue allografts, and a range of consumer products. Co-60 is used in Gamma Knife treatment of brain tumors in over 70,000 patients annually. Co-60 is also used to preserve food and kill insects and pathogens that cause food-borne illness. Co-60 is effective, reliable, and predictable. Limitations of alternative sterilization technologies include complex equipment, toxicities, incompatibilities with plastic, and physical hazards. Alternative ionizing radiation sources for wide-reaching applications, including e-beam and x-ray radiation, have advantages and drawbacks related to commercial scale capacity, penetrability, complexity and reliability. Identifying acceptable alternatives would require time, costs and lengthy regulatory review. FDA testing requirements and other hurdles would delay replacement of existing technologies and slow medical innovation, even delaying access to life-saving therapies. A phase-out would raise manufacturing costs, and reduce supply-chain efficiencies, potentially increasing consumer prices, and reducing supply. These consequences are poorly understood and merit additional research. Given Co-60’s importance across medical and non-medical fields, restrictions on Co-60 warrant careful consideration and evaluation before adoption.
Predictive Factors for the Positivity of the Sentinel Lymph Node in Malignant Melanoma
Authors: Crăciun Călin , Hankó-Bauer Orsolya , Benedek Zalán , Sorlea Sorin , Coroș Marius Florin , Georgescu Rareș 
Published: March 2018

Abstract
Malignant melanoma is a neoplasia that has its origin in the melanocytes, the melanin-synthesizing pigment cells present in the epidermis or sometimes in the dermis. Sentinel lymph node biopsy (SLNB) is the standard procedure used for staging patients with malignant melanoma in the majority of surgical centers in the world. With a probability of approximately 20% of finding positive lymph nodes, it spares a large number of patients of a complete lymphatic dissection. The aim of this study is to evaluate the factors that can predict the positivity of sentinel lymph nodes in malignant melanoma patients. We performed a retrospective study analyzing the histopathologic reports of patients who underwent SLNB for malignant melanoma between 2012 and 2015. There were 32 patients identified, out of which only three (9.37%) had positive SLN, so the majority of our patients were spared of regional lymphatic dissection. In our series, lymphatic invasion (p = 0.01), Breslow index >4 mm (p = 0.0064), AJCC staging (p = 0.0008), the presence of precursory lesions (p = 002), and microsatellitosis (p = 0.017) were predictive factors for the positivity of the SLN in malignant melanoma patients. Although our results are similar to those published in the literature, we consider that larger cohort studies should be performed to consolidate our results.
Chalk-induced Lung Fibrosis — Case Report
Authors: Szász Zsuzsánna Ágnes , Székely-Vass Enikő , Horváth Gyopár , Hozoi Mădălina 
Published: March 2018

Abstract

Introduction: Our article underlines the importance of a good professional anamnesis, knowing all the chemical components with which the patient had been exposed to during her active life as a teacher.

Case presentation: A 64-year-old female patient, teacher for 27 years, who had been retired for six years, presented cough with white phlegm and shortness of breath occurring during physical exertion, diffuse thoracic pain, and fatigue. Several lung functional tests were performed, which established the diagnosis of irreversible minor mixed ventilatory dysfunction. In order to establish the etiology of the patient’s symptoms, multiple clinical, laboratory, imaging, and functional investigations were performed including a chest radiograph, pulmonary functional testing, bronchial reversibility testing, a thoracic CT scan, fibrobronchoscopy, alveolar-capillary diffusion capacity measurement, otorhinolaryngology examination, thyroid ultrasound, as well as a cardiological consult. Finally, a positive diagnosis was established: bronchial hyperreactivity syndrome, chalk dust-induced diffuse pulmonary fibrosis.

Conclusion: An essential part of clinical practice is a proper anamnesis, including detailed information on the professional history and exposure, as well as the composition of the dust/particles with which the patient had been in contact with.
Time parallelization scheme with an adaptive time step size for solving stiff initial value problems
Authors: Bu Sunyoung 
Published: March 2018

Abstract
In this paper, we introduce a practical strategy to select an adaptive time step size suitable for the parareal algorithm designed to parallelize a numerical scheme for solving stiff initial value problems. For the adaptive time step size, a technique to detect stiffness of a given system is first considered since the step size will be chosen according to the extent of stiffness. Finally, the stiffness detection technique is applied to an initial prediction step of the parareal algorithm, and select an adaptive step size to each time interval according to the stiffness. Several numerical experiments demonstrate the efficiency of the proposed method.
Assessment of LVEF using a new 16-segment wall motion score in echocardiography
Authors: Lebeau Real , Serri Karim , Di Lorenzo Maria , Sauvé Claude , Van Le Hoai Viet , Soulières Vicky , El-Rayes Malak , Pagé Maude , Zaïani Chimène , Garot Jérôme , Poulin Frédéric 
Published: March 2018

Abstract

Background: Simpson biplane method and 3D by transthoracic echocardiography (TTE), radionuclide angiography (RNA) and cardiac magnetic resonance imaging (CMR) are the most accepted techniques for left ventricular ejection fraction (LVEF) assessment. Wall motion score index (WMSI) by TTE is an accepted complement. However, the conversion from WMSI to LVEF is obtained through a regression equation, which may limit its use. In this retrospective study, we aimed to validate a new method to derive LVEF from the wall motion score in 95 patients.

Methods: The new score consisted of attributing a segmental EF to each LV segment based on the wall motion score and averaging all 16 segmental EF into a global LVEF. This segmental EF score was calculated on TTE in 95 patients, and RNA was used as the reference LVEF method. LVEF using the new segmental EF 15-40-65 score on TTE was compared to the reference methods using linear regression and Bland–Altman analyses.

Results: The median LVEF was 45% (interquartile range 32–53%; range from 15 to 65%). Our new segmental EF 15-40-65 score derived on TTE correlated strongly with RNA-LVEF (r = 0.97). Overall, the new score resulted in good agreement of LVEF compared to RNA (mean bias 0.61%). The standard deviations (s.d.s) of the distributions of inter-method difference for the comparison of the new score with RNA were 6.2%, indicating good precision.

Conclusion: LVEF assessment using segmental EF derived from the wall motion score applied to each of the 16 LV segments has excellent correlation and agreement with a reference method.
PENGEMBANGAN PERANGKAT LUNAK ANTAR-MUKA INSTRUMEN MOTIWALI (TIDE GAUGE) UNTUK ANALISIS DATA PASANG SURUT
Authors: Khatimah Husnul , Jaya Indra , Saleh Atmadipoera Agus 
Published: March 2018

Instrumen MOTIWALI adalah alat untuk mengukur perubahan elevasi muka laut berbasis akustik, yang telah berhasil dikembangkan di Laboratorium Instrumentasi Kelautan ITK-IPB. Data hasil perekaman alat ini perlu dianalisis secara detail dengan membuat program untuk menentukan karakteristik komponen pasang-surut (pasut). Tujuan dari penelitian ini adalah untuk mengembangkan program antar-muka (software) yang dapat menganalisis data deret-waktu pasut dengan metode Admiralty, sehingga diperoleh komponen utama pasut serta menampilkan prediksinya. Pengembangan software mencakup empat modul, yaitu modul filter data untuk melakukan parsing dan pengelompokan data, modul Admiralty untuk analisis data pasut, modul Formzahl untuk penentuan tipe pasut, dan modul prediksi pasut. Data yang digunakan untuk uji-analisis software ini adalah data elevasi laut karena pasut hasil perekaman MOTIWALI selama 15 hari di Perairan Pulau Pramuka, Kep. Seribu. Perbandingan nilai amplitude dan fase komponen pasut antara hasil penelitian ini dengan data Dishidros, serta metode harmonik least-squared diperoleh nilai galat kuadrat terkecil (RMSE) sebesar 1.89 cm dan 102.27°, yang berarti akurasi hasil analisis dengan software ini cukup tinggi. Jenis pasut di lokasi studi adalah harian tunggal (F=4.43), yang sesuai dengan penelitian sebelumnya. Modul prediksi fluktuasi pasut menampilkan hasil prediksi pasut yang memberikan informasi bermanfaat bagi aktivitas di kawasan studi.
TERSİYER BİR MERKEZDE TERM VAJİNAL MAKAT DOĞUMLARIN RETROSPEKTİF ANALİZİ
Authors: Eser Ahmet , Albayrak Betül , Tayyar Ahter Tanay , Kılıççı Çetin , Karakuş Resul , Yayla abide Çiğdem , Sağıroğlu Gülhan , Eroglu Mustafa 
Published: March 2018

Amaç: Bu çalışmanın amacı term vajinal makat doğumların maternal ve fetal
sonuçlarını değerlendirmektir.Yöntem: Bu çalışmada Ocak 2014-Aralık 2017 tarihleri arasında kliniğimize doğum
için başvuran term gebelerden vajinal yolla doğum yapan makat gebelerdeki
maternal ve fetal sonuçlar değerlendirildi. Çalışma süresinde kliniğimizde 45
vajinal makat doğum gerçekleştiği saptandı.
Maternal demografik veriler; yaş, gravida, parite, gestasyonel hafta ve
maternal travma değerlendirildi. Fetal sonuçlar olarak doğum kilosu, 1. ve 5.
dakika APGAR skorları, 5.dakika APGAR skorunun 7 olması, yenidoğan yoğun bakım ihtiyacı
olup olmaması ve fetal travma ve neonatal ölüm varlığı değerlendirildi. Preterm makat doğumlar çalışmaya dahil
edilmedi.Bulgular: Çalışma süresince
45 term vajinal makat doğum
gerşekleşmiştir. Gebelerin 2(%4) sinde maternal travmaya rastlanmış,
yenidoğanların 3(%7)ünde doğum travması
görülmüştür. 2(%6) yenidoğan da 5.dakika APGAR7 idi. 13(%29) yenidoğana yoğum bakım
ihtiyacı gerekmiştir, bunların 4(%9) ünde fetal anomali mevcuttu. Neonatal ölüm
1(%2) yenidoğanda görülmüştür. Bu olguda fetal anomali nedeniyle
kaybedilmiştir.Sonuç: Term makat gebelerde planlanmış sezeryanla doğum yapıldığında mortalite
ve morbiditede azalma sağlanabilir. Düşük risk grubuna sahip gebelerde yakın
fetal moniterizasyon ve tecrübeli hekimlerin varlığında vajinal yolla doğum
sezeryanla doğuma alternatif olabilir.
Preparation of Nano Polymeric Thiophenes and Characterization of the Structures
Authors: SİVRİKAYA Sezen , DURMUŞ Sefa , DALMAZ Aslıhan 
Published: March 2018

This
article describes a chemical oxidative polymerization for the preparation of
nano polymeric thiophene by using FeCl3 as oxidant. 2-thiophenecarboxaldehyde
(2-THCA) as monomer was used at polymerization process. The structure of
synthesized nano polymeric thiophene was confirmed by scanning electron microscopy (SEM), Fourier
transform infrared spectroscopy (FTIR), Thermogravimetric analysis (TGA), Raman
Spectroscopy, and elemental analysis of C, H, O and S. SEM images showed that
the poly(2-thiophenecarboxaldehyde) (PTHCA) was synthesized in nanoscale and had
a homogeneous and smooth structure. The size of the synthesized nano particles
was not more than 35 nm. Thermal analysis of nano polymeric thiophene showed
thermally stable up to 512 OC. When elemental analysis results of PTHCA were
examined, it was seen that the obtained data after the synthesis of nano
polymeric thiophene and the determined data theoretically were agree with each
other.
Clinostomum sp. (Digenea: Clinostomidae) e Ascocotyle sp. (Digenea: Heterophyidae): metacercárias com potencial zoonótico em peixes da bacia do Rio Tramandaí­­, sul do Brasil
Authors: POZZA Alice , LIMA Fábio , HAAS Mateus Luís , LEHMANN ALBORNOZ Pablo Cesar 
Published: March 2018

Os helmintos pertencentes í­Â Classe Trematoda têm grande importí­¢ncia na ictioparasitologia, onde a Subclasse Digenea apresenta parasitos com potencial zoonótico. A famí­­lia Heterophyidae é responsável pela heterofidí­­ase e no Brasil essa doença é causada por trematódeos do gênero Ascocotyle (Phagicola), comumente conhecida como fagicolose, transmitida de peixes í­Â s aves e mamí­­feros. Já as larvas de Clinostomum, presentes na musculatura de peixes, tem aves piscí­­voras como seus hospedeiros definitivos, e podem parasitar seres humanos acidentalmente, causando laringofaringite parasitária e morte por asfixia. Este estudo busca quantificar a presença de parasitos digenéticos das famí­­lias Heterophyidae e Clinostomidae com potencial zoonótico em peixes da bacia do rio Tramandaí­­/RS. Os peixes foram adquiridos de pescadores do municí­­pio de Terra de Areia/RS, entre julho de 2016 e maio de 2017 e necropsiados í­Â procura de parasitas. Os digenéticos foram fixados, corados e montados em lí­¢minas para identificação. Índices parasitológicos foram calculados. Astyanax spp. foram positivos para Ascocotyle enquanto Geophagus brasiliensis apresentou-se infectado por Clinostomum sp. Sendo assim, os resultados obtidos sugerem risco de infecção para a população regional consumidora.
Increasing Burden of Total Hip Arthroplasty Revisions in Patients Between 45 and 64 Years of Age
Authors: Rajaee Sean S. , Campbell Joshua C. , Mirocha James , Paiement Guy D. 
Published: March 2018

Background:
This study provides a comprehensive analysis of total hip arthroplasty (THA) revisions in the U.S. from 2007 to 2013.

Methods:
International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes were used to identify all THA revisions in the Nationwide Inpatient Sample (NIS) from 2007 to 2013. The diagnoses leading to the revisions, types of revisions, major inpatient complications, and hospital and patient characteristics were compared between 2007 and 2013. Multivariable logistic regression models were used to calculate adjusted odds ratios (ORs) for complications in 2013 versus 2007.

Results:
This study identified 320,496 THA revisions performed between 2007 and 2013. From 2007 to 2013, the THA revision rate adjusted for U.S. population growth increased by 30.4% in patients between 45 and 64 years of age and decreased in all other age groups. The rate of surgically treated THA dislocations decreased by 14.3% from 2007 to 2013 (p < 0.0001). The mean length of the hospital stay and hospital costs for THA revision were significantly lower in 2013 than in 2007 (4.6 versus 5.8 days and $20,463 versus $25,401 both p < 0.0001). A multivariable model showed that the odds of a patient undergoing THA revision having the following inpatient complications were significantly lower in 2013 than in 2007: deep vein thrombosis (OR = 0.57, p = 0.004), pulmonary embolism (OR = 0.45, p = 0.047), myocardial infarction (OR = 0.52, p = 0.003), transfusion (OR = 0.64, p < 0.0001), pneumonia (OR = 0.56, p < 0.0001), urinary tract infection (OR = 0.66, p < 0.0001), and mortality (OR = 0.50, p = 0.0009). Notably, the odds of being discharged to a skilled nursing facility were also lower in 2013 than in 2007 (OR = 0.71, p < 0.0001).

Conclusions:
The THA revision rate has significantly increased in patients between 45 and 64 years of age. However, the rate of surgically treated THA dislocations has decreased significantly. This may indicate that evolving techniques and implants are improving stability. The rate of inpatient complications following THA revision also decreased significantly from 2007 to 2013.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Karakterisasi Sifat Morfologi dan Ketahanan terhadap Penyakit Hawar Daun Bakteri pada Beberapa Varietas Padi
Authors: Yuliani Dini , Wening Rina Hapsari , Sudir Sudir 
Published: March 2018

<p>Bacterial leaf blight, caused by Xanthomonas oryzae pv oryzae (Xoo) is common disease on rice crop in Indonesia. Resistance variety when available, would be a good control measure to the disease, which could be easily adopted by farmers. Source of gene for resistance needs to be identified among rice genotypes, to be used as parents in the breeding program. This research was aimed to characterize the morphological traits and the degree of resistance among rice genotypes against Xoo pathotype III, IV, and VIII. The experiment was conducted at Sukamandi experimental field of Indonesian Center for Rice Research, during the wet season of 2012/2013 and dry season of 2013, using a randomized factorial design. The first factor was three Xoo pathotypes i.e. pathotype III, IV, and VIII, the second factor was 20 rice genotypes including three check varieties, i.e. Ciherang, Inpari 13, and Angke. Observations of morphological and agronomic characters were done on rice plants started from primordial to grain ripening phase. Observations on BLB disease severity were done by measuring the longest symptoms on the leaves at two, three, and four weeks after inoculation. The morphological characters of the isogenic lines showed moderate leaf surface type with an open habitus (60o). Plant height ranged from 99 to 190 cm, maturity between 109 to 157 days after sowing, and the number of tillers was 9-23 tillers/hill. Against the Xoo pathotype III, IV, and VIII, three genotypes of near isogenic lines i.e. IRBB 60, IRBB 61, and IRBB 55 each was resistance, not significantly different from resistance check variety Angke, in two cropping seasons. All three isogenic lines can be used as parent to develop new resistant variety to bacterial leaf blight.</p>
Spatiotemporal trend analysis of rainfall and temperature, and its implications for crop production
Authors: Worku Tesfa , Khare Deepak , Tripathi S. K. 
Published: March 2018

Abstract
Global warming is a significant global environmental problem in the 21st century. The problem is high in developing countries, particularly sub-Saharan countries in which the majority of the population live on rainfed agriculture. The present study aimed to undertake spatiotemporal analysis of seasonal and annual rainfall and temperature and its implications. The MK test, Sen's slope and precipitation concentration index (PCI) were applied. Finally, Pearson correlation analysis between climatic variables and crop production was analysed. The Mann–Kendall test results showed that the annual and seasonal rainfall trend was highly variable. The minimum and maximum temperatures have increased by 0.8 and 1.1 °C/year, respectively. Based on PCI results, rainfall during the summer and spring seasons is moderately distributed as compared to annual and winter season rainfall. Based on these observations, the rainfall pattern and distribution of the area could be classified as irregular and erratic distribution. Results of correlation analysis between monthly and seasonal rainfall with crop production were insufficient to conclude the impact of rainfall and temperature on crop production. In view of this, the incidence of food shortage is a common occurrence. Therefore, depending on the historical trend of rainfall variability and prolonged temperature increase, appropriate coping and adaptation strategies need to be encouraged.
INTERAKSI GENOTIPE X MUSIM KARAKTER FISIOLOGI LATEKS DAN DAYA HASIL BEBERAPA GENOTIPE KARET HASIL PERSILANGAN TAHUN 1992
Authors: Sayurandi Sayurandi , Wirnas Desta , Woelan Sekar 
Published: March 2018

Latex physiology characters and yield potential of rubber tree (Hevea brasiliensis) are determined by genetic factor, environments, and genotype x environment interaction. The environmental conditions greatly influence latex physiology characters and latex yield potential are the monthly rainfalls. The objective of the research was to get information about the performance of latex physiology characters and yield potential of some promising rubber genotypes of crossing results in 1992 in dry and wet months period. The experimental design used was randomize completely design (RCD) with two factors and three replications. The first factor was genotypes consisted of 15 genotypes and 2 control clones of PB 260 and RRIC 100. The second factor was season consisted of the wet months period (August - November 2015) and dry months period (January - March 2016) based on classification of Oldeman. The research result showed that the genotype x season interaction effect was significant to sucrose content, inorganic phosphate content, thiol content, latex flow rate, plugging index, yield index, and latex yield potential. Genotype HP 92/542 was a more tolerant to seasonal changes and this genotype had high latex yield and more stable. The genotype can be developed as a new genetic material of superior rubber clone. Genotype HP 92/726 was also tolerant to seasonal changes but the genotype had low latex yield. The genotype HP 92/838 was intolerant to seasonal changes and the genotype had low latex yield and unstable.
Natureza um pouco morta, um tanto viva [Life: a little still and yet alive]
Authors: Paim Claudia 
Published: March 2018

Ensaio é também experimento. Ensaio-experiência-corpo. Arranjos entre um corpo maduro e marcado e elementos deslocados da vida cotidiana. Uma busca por composição onde a pele é o único elemento constante.

__________________________________________
An essay is also an experiment. Essay-experience-body. Arrangements between a
mature and marked body and elements displaced from everyday life. The search for composition
where the skin is the only constant element.
A expressão do múltiplo pelo corpo da pintura.
Authors: Paquet Bernard 
Published: March 2018

Este ensaio apresenta uma experimentação poética e reflexiva que
constrói uma imagem do humano do futuro (pós-humano) com base numa
anatomia sem gênero nem pele. Para multiplicar este corpo, em pintura, dois
parâmetros são considerados: os elementos anatômicos que se prestam
facilmente ao múltiplo e variações, depois a ausência de dualidade.
Becoming an Artist: the work of art beyond itself. An interview with Túlio Pinto
Authors: Caldas Felipe Bernardes , Pinto Túlio 
Published: March 2018

The concern about how art and artists converse with
production systems is not recent. It dates back at least to the
19th century. That interest gave rise to many arguments as well
as functional attributions for the roles played by art and artists.
How do artists converse with, share or challenge today’s capitalist
production system, which would be centered on information,
immateriality and the fusion of work and life? This interview with
Túlio Pinto provides a reflective platform to think about what it
means to work with art within a dialogue between the local and
the global, the systems, the markets and the circuits in which
contemporary art and its agents are placed and which they cross.