bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ocean current signals propagation along the Outer Banda Arcs
Authors: Masoleh V C , Atmadipoera A S , Purba M 
Published: May 2019

AbstractEquatorial Pacific Rossby waves may enter into the interior of the Indonesian Throughflow (ITF)’s eastern pathway, such as along the Outer Banda Arcs (OBA). This study aimed to investigate the dynamics of the ITF along the OBA channel from Ceram Sea to Aru Basin to Western Timor Passage. This is necessary because it can provide information about the physical oceanographic conditions, especially the dynamics of the current in the study area. Based on the Hovmoller diagram, a propagation of the signal from kinetic energy was found along the OBA which its phase speed theoretically appears to be trapped in Rossby waves, because of the similarity of the speed phase. The normal mode analysis shows that the oscillation in Ceram Sea, Aru Basin, and Timor Passage has the same pattern based on the potential density and Brunt-Vaisala frequency profiles. The transport’s coherence between Indo-Pacific meridional winds and transport volume in Aru Basin shows a strong coherence value (0.94) which is dominated by an annual variability with a period of 341 days. The results suggest that zonal winds along the equator Pacific Ocean act as a remotely forced Rossby waves that propagate westward, entering the interior of Indonesian Seas.
Influence of salt addition and freezing-thawing on particle size and zeta potential of nano-chitosan
Authors: Nugraheni P S , Soeriyadi A H , Sediawan W B , Ustadi  , Budhijanto W 
Published: May 2019

Abstract
Antibacterial properties of nano-chitosan used for fish preservation would achieve optimum effect when combined with cooling. Applying nano-chitosan incorporated in ice can reduce the cooling cost of conventional fish industry. On the other hand, during fish handling, nano-chitosan has a high probability to be contaminated by salt in seawater. This study was aimed to test the effect of salt and freezing-thawing on nano-chitosan antibacterial activity. Nano-chitosan was prepared using ionic gelation and polyelectrolyte complex methods. NaCl (3%m/v) was added into nano-chitosan solutions to evaluate the effect of salt. Chitosan solution in diluted acetic acid was also tested as blank. The effect of freezing was undertaken by placing nano-chitosan and chitosan solution in the freezer until the solutions were completely frozen and then thawing the frozen solution in ambient temperature. The addition of salt not only reduced the particle size but also reduced zeta potential due to the possible neutralization. It also might reduce its antibacterial activity. Freezing effect increased particle size because low temperature triggered particle agglomeration but it did not show any changes in zeta potential. The result of this preliminary study indicated that nano-chitosan ice would give more benefit as fish preservative compared to plain ice.
Characterization of Trimethylamin-N-Oxide Demethylase (TMAOase) of Lizardfish from Indonesian Waters
Authors: Nurhayati T , Nurilmala M , Nuraini A 
Published: May 2019

Abstract
Formation of formaldehyde in fish can occur naturally through the breakdown of trimethylamine oxide (TMAO) become formaldehyde and the dimethylamine by-product in the fish during the postmortem phase by trimethylamine-N-oxide demethylase (TMAOase). The objective of this study was to characterize TMAOase which isolated from Saurida tumbil. The study was carried out by homogenizing of fish muscle using Tris-acetate buffer (pH 7.0) and centrifuged 10,000xg for 30 minutes. The supernatant was then added 1 M NaCl up to pH 4.5 and centrifuged at again. The supernatant was neutralized and heated at 80°C for 20 minutes, then centrifuged at 10,000xg for 30 minutes and then characterized by temperature, pH, cofactor effect on enzyme activity, and molecular weight. The same supernatant and then was dialyzed for 2 hours and determined its enzyme activity, protein concentration, and molecular weight. The result showed that TMAOase enzyme had optimum activity at pH 7 and temperature at 50°C and cofactor combination of cysteine, ascorbate, and FeCl2 could increase TMAOase activity. The dialysate had yield 3.71%, 1.78 fold purification, and molecular weight 20 kDa.
The elasticity of mangrove ecosystem services in the Jor Bay, Indonesia
Authors: Nurokhmah I , Adrianto L , Sjafrie N D M 
Published: May 2019

Abstract
The mangrove ecosystem in Jor Bay is described as a socio-ecological system that has a multi-puidrose function and is related to ecosystem services. The concept of ecosystem services is based on the relationship between ecosystem quality and human well-being. But this relationship is complicated and we have a poor understanding of how the quality of mangrove ecosystems can affect human well-being, and how human well-being changes in response to increase or decline in ecosystem change. Therefore, an elasticity analysis is conducted to determine that linkage mechanism and simplify the complexities and context dependency of the ecosystem quality and human well-being relationship. The study was conducted in April-May 2018 in Jor Bay, East Lombok Regency, West Nusa Tenggara. The approach that was used in this research is an Elasticity Model. The results obtained are ecosystem services that are most widely used in Jor Bay, especially in non-direct extraction use. The general condition of ecosystem services in Teluk Jor is still in a suidrlus condition (using a capacity matrix, demand matrix and supply matrix). After mapping out the elasticity, it was found that the mangrove ecosystem in Jor Bay has a high positive elasticity.
Trophic structure of reef fishes and relationship of corallivore fishes with hard coral in Kepulauan Seribu, Jakarta
Authors: Prabowo B , Fahlevy K , Putra N F D , Rizqydiani M , Rahman B M K , Habibie A , Subhan B , Madduppa H 
Published: May 2019

Abstract
Corallivore became one of the biotic components that relate with coral coverage. The objective of this study was to determine the trophic structure of reef fishes, as well as the relationship between corallivores and hard corals in the northern part of Kepulauan Seribu. Reef fish species and benthic coverage were assessed using underwater visual census (UVCs) and Line Intercept Transect (LIT). The results showed that there were 120 reef fish species belonging to 7 trophic groups and 19 families. Pomacentridae and Labridae are the most abundant fish families. Based on reef fish components, Sepa Besar reef fish characteristics were dissimilar than the other sites. The highest coral cover was found in Pelangi Island, which related with the high abundance of corallivores. An abundance of corallivore groups showed a positive correlation (R2 = 0.7786) with hard coral cover. The abundance and diversity of reef fish were affected by the availability and variety of food. Our study shows that coral covers affect the abundance of corallivore fishes. Variability and existence of food for reef fishes are really important for resort priprietors to be aware of especially for those who manage diving and snorkeling activities.
The impact of coastal degradation on mangrove ecosystem in North Karawang coastal area
Authors: Pranoto A K , Haryani E B S , Amdani  , Tanjung A 
Published: May 2019

Abstract
Coastal degradation can be observed as destruction of mangrove area. The impact of mangrove destruction is evidenced by a significantly eroded area. Further impacts included lessened biodiversity, especially in the mangrove ecosystem. This study aimed to determine the impact of coastal damage to the mangrove ecosystem in Karawang coastal areas. The mangrove degradation was identified from changes in mangrove covered area by utilizing data from several Landsat TM satellite imagery and ground check equipped with GPS and Google Earth applications. Data from the inventory of mangrove area issued by the Perhutani of KPH Purwakarta 2017 were also used as supplement in determining the extent of destruction. From satellite imagery, the mangrove area in 2017 was 258 hectares. This area was only approximately 3% of the total area of mangrove protected areas assigned by the Regency Spatial Plan. Compared to the condition in 2009, the coastal destruction was significant. The worst mangrove degradation occurred in the sub-districts of Cibuaya, Tempuran, and Cilamaya Wetan. The coastal communities were aware of the problem. They understood that this problem was caused by coastal abrasion and land use change, wild catch, milkfish and shrimp aquaculture, salt ponds, rice farms, and tourism.
Protein profiles and DNA isolation of hemolymph gonggong snail (Strombus sp.) from Bintan
Authors: Viruly L , Andarwulan N , Suhartono M T , Nurilmala M 
Published: May 2019

Abstract
Gonggong snail is one of the famous and highly-priced local seafood in Bintan Island, Riau Islands Province. It is an icon of Tanjung Pinang city. Until now, general research on Bintan gonggong snail is scarce, even if it has the potential to be used for aquaculture, functional food ingredient, and medicine. Research of bioactive peptides are mostly performed using the group of molluscs (gastropods). The research on protein profiles and DNA isolation has never been studied in hemolymph Bintan gonggong snail. This research was aimed to identify protein profiles and DNA isolation in hemolymph Bintan gonggong snail (Strombus sp). Protein profiling used SDS-PAGE. DNA isolation used Qiagen DNeasy methods, while PCR used primer histon H2A. Identification on protein profiles displayed that thin-shelled and thick-shelled gonggong snails had a similiarity value of 37 kDa, whereas the other protein profiles were different. The types of protein of Bintan gonggong snails were predicted to be histone proteins. The DNA of hemolymph Bintan gonggong snails had a similiarity value of 75 bp fragment histon. It is predicted as protein histon H2A and will be developed potentially as antimicrobial peptides (AMPs).
Growth performance of white shrimp Litopenaeus vannamei fed with Various dosages of prebiotic honey
Authors: Widanarni  , Putri F N , Rahman  
Published: May 2019

Abstract
The intensive culture system of white shrimp with high stocking density leads to slow shrimp growth performance. An alternative way to increase the growth performance of white shrimp is using a prebiotic. This study was aimed to evaluate the effectiveness of honey as a prebiotic through commercial feed to improve the growth performance of white shrimp. The white shrimp were reared with comercial feed that have been enriched with honey. This study consisted of four treatments, which were: control (without prebiotic), and the giving of honey at dosages of (A) 0.2%; (B) 0.4%; (C) 0.6%, each treatment with three replications. The average weight of vaname shrimp used was 0.44±0.11 g, maintained with a density of 270 shrimp/m-3 with an aquarium size of (60×30×30 cm3). The results of this study indicate that honey with a dosage of 0.6% results in the best growth performance with a growth rate of 0.14±0.002 g/day, specific growth rate of 4.70±0.02%/day, and feed conversion ratio of 1.53±0.02.
Comprehensive Geriatric Assessment in the perioperative setting; where next?
Authors: Dhesi Jugdeep , Moonesinghe S Ramani , Partridge Judith 
Published: May 2019

Abstract
Comprehensive Geriatric Assessment (CGA) is being employed in the perioperative setting to improve outcomes for older surgical patients. Traditionally CGA is delivered by a geriatrician led multidisciplinary team but with the acknowledged workforce challenges in geriatric medicine, it has been suggested that non-geriatricians may be able to deliver CGA. HOW-CGA developed a toolkit to facilitate the delivery of CGA by non-geriatricians in the perioperative setting. Across two hospital sites uptake and implementation of this toolkit was limited by a potential lack of face validity, behavioural and cultural barriers and an acknowledgement that geriatric medicine expertise is key to CGA and optimisation. In-keeping with this finding there has been an observed expansion in geriatrician led CGA services for older surgical patients in the UK. In order to demonstrate the effectiveness of perioperative CGA services, implementation science should be combined with health services research methodology and the use of big data through linked national audit.
Device-Specific Findings of Imprinted-Texture Breast Implants: Characteristics, Risks, and Benefits
Authors: Wixtrom Roger N , Garadi Vikram , Leopold John , Canady John W 
Published: May 2019

Abstract

Background
The relative risks and benefits of various textured breast implants are the focus of considerable discussion. Studies have suggested different risk-benefit profiles for different implant surface topographies.

Objectives
The study aim was to provide device-specific, quantitative information on Mentor’s imprinted Siltex Textured breast implants with respect to textured surface characteristics and ISO 14607 classification, risk of breast implant–associated anaplastic large cell lymphoma (BIA-ALCL), and risk-reduction benefits relative to smooth implants.

Methods
Surface metrology was performed. Data for smooth and Siltex implants from the prospective MemoryGel Core Study were evaluated by Kaplan-Meier analysis for the most frequently occurring postoperative complications in augmentation and reconstruction leading to subsequent reoperation.

Results
The overall average surface roughness for Siltex MemoryGel and MemoryShape implants was 29.5 and 36.1 µm, respectively. A statistically significantly lower rate of reoperation in patients with Siltex compared with smooth devices over 10 years was observed for both capsular contracture in subglandular primary augmentation patients (2.02% vs 19.84%) and for asymmetry in primary reconstruction patients (3.88% vs 11.1%).

Conclusions
Surface analysis demonstrated that Siltex implants fall within the ISO 14607 category of “microtexture” breast implants. These devices exhibited a rare risk of BIA-ALCL (0.0012%) based on the most extensive data available. Relative to smooth implants, these Siltex devices provided risk-reduction benefits for the most common reason of reoperation in patients who underwent primary augmentation (capsular contracture) or primary reconstruction (asymmetry) in the Core Study. These findings provide valuable risk-benefit information for surgeons and their patients.

Level of Evidence: 2
The evolution of two types of play
Authors: Smaldino Paul E , Palagi Elisabetta , Burghardt Gordon M , Pellis Sergio M 
Published: May 2019

AbstractPlay is an important and understudied class of phenomena that likely serves a critical role in the ontogeny and maintenance of fitness-enhancing behaviors. Many species exhibit little or no play. Among those animals that do play, some exhibit only very simple forms, while others engage in complex play both solitarily and socially. Likewise, some animals play only as juveniles, while others continue to play as adults. We propose a general framework to explain interspecies variation in the evolution and emergence of simple vs. complex forms of play, supported by both a review of the empirical evidence and a novel mathematical model. The emergence of play requires that initial investment returns benefits that sufficiently compensate the opportunity costs associated with simple play. The subsequent evolution of complex play depends upon the interplay of several life-history factors related to the benefits, costs, and time course of play investment. We conclude with implications for understanding the evolution of play across the animal kingdom.
ACME: pan-specific peptide–MHC class I binding prediction through attention-based deep neural networks
Authors: Hu Yan , Wang Ziqiang , Hu Hailin , Wan Fangping , Chen Lin , Xiong Yuanpeng , Wang Xiaoxia , Zhao Dan , Huang Weiren , Zeng Jianyang 
Published: May 2019

Abstract

Motivation
Prediction of peptide binding to the major histocompatibility complex (MHC) plays a vital role in the development of therapeutic vaccines for the treatment of cancer. Algorithms with improved correlations between predicted and actual binding affinities are needed to increase precision and reduce the number of false positive predictions.

Results
We present ACME (Attention-based Convolutional neural networks for MHC Epitope binding prediction), a new pan-specific algorithm to accurately predict the binding affinities between peptides and MHC class I molecules, even for those new alleles that are not seen in the training data. Extensive tests have demonstrated that ACME can significantly outperform other state-of-the-art prediction methods with an increase of the Pearson correlation coefficient between predicted and measured binding affinities by up to 23 percentage points. In addition, its ability to identify strong-binding peptides has been experimentally validated. Moreover, by integrating the convolutional neural network with attention mechanism, ACME is able to extract interpretable patterns that can provide useful and detailed insights into the binding preferences between peptides and their MHC partners. All these results have demonstrated that ACME can provide a powerful and practically useful tool for the studies of peptide–MHC class I interactions.

Availability and implementation
ACME is available as an open source software at https://github.com/HYsxe/ACME.

Supplementary information
Supplementary data are available at Bioinformatics online.
Towards a new classification of tribe Stachydeae (Lamiaceae): naming clades using molecular evidence
Authors: Salmaki Yasaman , Heubl Günther , Weigend Maximilian 
Published: May 2019

AbstractStachydeae, comprising c. 470 species, are one of the most diverse and taxonomically puzzling groups in Lamioideae. In the present study, the phylogenetic relationships in the Eurystachys clade (a phylogenetic name for all genera attributed to Stachydeae except Melittis) were reconstructed utilizing nuclear ribosomal DNA sequences (nrETS, 5S-NTS) from 148 accessions in 12 genera. Our phylogenetic results recovered Stachys as paraphyletic with numerous traditionally recognized genera nested in it. A broadly defined Eurystachys clade, however, was monophyletic. Unlike previous studies, the present study was able to resolve the group into 12 well-supported clades, named here as (1) Eriostomum, (2) Stachys, (3) Prasium, (4) Setifolia, (5) Distantes, (6) Burgsdorfia, (7) Hesiodia, (8) Empedoclia, (9) Sideritis, (10) Marrubiastrum, (11) Swainsoniana and (12) Olisia. These 12 clades were formally named in a phylogenetic nomenclature for the Eurystachys clade. Several infrageneric units were retrieved as monophyletic, namely Sideritis sections Burgsdorfia, Empedoclia and Hesiodia, Sideritis subgenus Marrubiastrum and Stachys sections Eriostomum (including Stachys section Mucronata) and Setifolia. The findings of this study also provide the basis for a future formal classification, with two options: (1) splitting of the Eurystachys clade into 12 monophyletic genera, all of them based on pre-existing genus names and redefined to encompass additional taxa, but without clear morphological apomorphies; or (2) lumping of all segregates into a broadly defined Stachys, including widely recognized and well-defined segregates such as Prasium and Sideritis.
Longitudinal trajectories of hospital performance across targeted cardiovascular conditions in the USA
Authors: Vaduganathan Muthiah , McCarthy Cian P , Ayers Colby , Bhatt Deepak L , Kumbhani Dharam J , de Lemos James A , Fonarow Gregg C , Pandey Ambarish 
Published: May 2019

Abstract

Aims
Thirty-day risk standardized readmission and mortality rates (RSRR, RSMR) are key determinants for hospital performance for cardiovascular conditions such as acute myocardial infarction (AMI) and heart failure (HF). We evaluated whether individual hospitals in the USA perform similarly for HF and AMI over time based on readmission and mortality metrics.

Methods and results
A total of 1950 hospitals in the USA with continuous participation in the Centers for Medicare and Medicaid Services (CMS) public reporting programme between 2010 and 2016 were identified. Latent mixture modelling was used to define performance trajectory groups. Overall, there were consistent declines in the RSMR (16.1–14.0%) and RSRR (20.3–16.6%) for AMI from 2010 to 2016. For HF, RSRR declined over time (25.1–21.7%), while there was a modest increase in RSMR (11.3–12.0%); parallel findings were observed across performance trajectory groups. The proportion of best performing centres for HF care that were also best performers for AMI care based on the 30-day RSMR and 30-day RSRR metric was 54% and 35%, respectively. Furthermore, the discordance rate between the best and worst performers for both conditions was low (&lt;2% for both 30-day outcomes).

Conclusion
In the USA, despite variation in baseline hospital-level outcomes, hospitals had consistent longitudinal trajectories (worsening or improvement) across conditions and metrics. Hospitals identified as high performing were frequently similar across target conditions and over time, suggesting that performance may be driven by systems of care influencing different disease states in a comparable manner.
A Renewed Focus on GDF11 Level Fluctuation in Human Serum in Relation to Physical Examination Indicators
Authors: Liang Xiaolin , Dou Xiaowei , Tian Long , Li Quanyang 
Published: May 2019

Abstract
Growth and differentiation factor 11 (GDF11) is a member of the transforming growth factor β superfamily. Previous studies have shown that GDF11 decreases with age and has antiaging effects; however, such reports are controversial. We choose 152 subjects covering a large age range (2 hours to 75 years) to measure serum GDF11. Twenty-two hematological variables and 13 biochemical values were measured. Pearson’s analysis found a significant correlation between GDF11 and age (p = .0000, r = .4898), as well as serum creatinine, uric acid, triglycerides, red blood cell count, hemoglobin, hematocrit, and platelet volume distribution width. GDF11 negatively correlated with aspartate transaminase, white blood cell count, platelet count, lymphocyte count, monocyte count, mean platelet volume, and plateletcrit. Interestingly, we found GDF11 increases in people aged 20–30 years, holds steady in people aged 30–50 years, and increases in people older than 50 years. The results suggest that GDF11 serves different roles along the life span. The current actual evidence supports that GDF11 is helpful to promote aging.
Are Self-perceptions of Aging Associated With Health Trajectories Among Middle-Aged and Older Adults?
Authors: Luo Meng Sha , Li Lydia W 
Published: May 2019

Abstract

Background and Objectives
Older adults’ health trajectory is often pictured as loss and decline. Recent literature has questioned this assumption. Conceptualizing health as a multidimensional construct, encompassing physical disabilities, functional limitations, chronic diseases, depressive symptoms, memory problems, and self-rated health, we investigated patterns of health trajectories among middle-aged and older adults in the United States. Moreover, we investigated the relationship between self-perceptions of aging (SPAs) and health trajectory patterns.

Research Design and Methods
We used latent class growth modeling to examine health trajectory patterns, based on longitudinal data with 4 measurement points over a 7-year period from a national sample of 10,212 middle-aged and older adults (aged 51 and older). Multinomial logit models were used to examine how health trajectory patterns were associated with baseline SPA.

Results
We identified 4 health trajectory patterns: accelerated aging, usual aging, depressed aging, and healthy aging. The full model shows that with each one-unit increase in negative SPA, the odds of belonging to an accelerated aging group, depressed aging group, and usual aging group (vs healthy aging group) increased by 26%, 17%, and 9%, respectively.

Discussion and Implications
The combination of health changes across different domains results in health trajectories that cannot be understood as simply a declining process. SPAs are associated with individuals’ trajectories of health.