bluuebunny/crossref_metadata_2025_split huggingface dataset:
Operation and Performance of Slocum Field Thermal Recovery Project
Authors: Hall A. L. , Bowman R. W. 
Published: November 2018

ABSTRACT
Shell Oil Company's Slocum Thermal Recovery Project is successfully recovering 19° API oil from the 500 foot deep Carrizo sand. In the eight years prior to initiation of steam injection, primary production recovered only 300,000 barrels of oil, or about 1 percent of the original oil-in-place. Three years of full scale operation have recovered 1.4 million barrels of oil, representing 4.7 percent of the original oil-in-place.
After pilot testing, injection was started into seven, 13-spot patterns in March 1967. To date, 13 additional patterns have been installed. The low injectivity of the oil sand precludes conventional water or steam drive processes; however, the underlying water layer provides a path for efficient heat communication and steam injection.
Among the problems encountered in this thermal operation are dehydration of complex emulsions, restricted hot well production performance, production of hydrogen sulfide gas, and production of organic solids.
Fast Photochemical Oxidation of Proteins Coupled with Mass Spectrometry
Authors: Shi Liuqing , Gross Michael L. 
Published: November 2018

Background:
Determination of the composition and some structural features of macromolecules
can be achieved by using structural proteomics approaches coupled with mass spectrometry
(MS). One approach is hydroxyl radical protein footprinting whereby amino-acid side
chains are modified with reactive reagents to modify irreversibly a protein side chain. The outcomes,
when deciphered with mass-spectrometry-based proteomics, can increase our knowledge of
structure, assembly, and conformational dynamics of macromolecules in solution. Generating the
hydroxyl radicals by laser irradiation, Hambly and Gross developed the approach of Fast Photochemical
Oxidation of Proteins (FPOP), which labels proteins on the sub millisecond time scale and
provides, with MS analysis, deeper understanding of protein structure and protein-ligand and protein-
protein interactions. This review highlights the fundamentals of FPOP and provides descriptions
of hydroxyl-radical and other radical and carbene generation, of the hydroxyl labeling of proteins,
and of determination of protein modification sites. We also summarize some recent applications
of FPOP coupled with MS in protein footprinting.

Conclusion:
We survey results that show the capability of FPOP for qualitatively measuring protein
solvent accessibility on the residue level. To make these approaches more valuable, we describe
recent method developments that increase FPOP’s quantitative capacity and increase the
spatial protein sequence coverage. To improve FPOP further, several new labeling reagents including
carbenes and other radicals have been developed. These growing improvements will allow oxidative-
footprinting methods coupled with MS to play an increasingly significant role in determining
the structure and dynamics of macromolecules and their assemblies.
Development of Synchrotron Footprinting at NSLS and NSLS-II
Authors: Bohon Jen 
Published: November 2018

Background:
First developed in the 1990’s at the National Synchrotron Light Source, xray
synchrotron footprinting is an ideal technique for the analysis of solution-state structure and
dynamics of macromolecules. Hydroxyl radicals generated in aqueous samples by intense x-ray
beams serve as fine probes of solvent accessibility, rapidly and irreversibly reacting with solvent
exposed residues to provide a “snapshot” of the sample state at the time of exposure. Over the last
few decades, improvements in instrumentation to expand the technology have continuously pushed
the boundaries of biological systems that can be studied using the technique.

Conclusion:
Dedicated synchrotron beamlines provide important resources for examining fundamental
biological mechanisms of folding, ligand binding, catalysis, transcription, translation, and
macromolecular assembly. The legacy of synchrotron footprinting at NSLS has led to significant
improvement in our understanding of many biological systems, from identifying key structural
components in enzymes and transporters to in vivo studies of ribosome assembly. This work continues
at the XFP (17-BM) beamline at NSLS-II and facilities at ALS, which are currently accepting
proposals for use.
Recent Advances in X-Ray Hydroxyl Radical Footprinting at the Advanced Light Source Synchrotron
Authors: Morton Simon A. , Gupta Sayan , Petzold Christopher J. , Ralston Corie Y. 
Published: November 2018

Background:
Synchrotron hydroxyl radical footprinting is a relatively new structural
method used to investigate structural features and conformational changes of nucleic acids and
proteins in the solution state. It was originally developed at the National Synchrotron Light Source
at Brookhaven National Laboratory in the late nineties, and more recently, has been established at
the Advanced Light Source at Lawrence Berkeley National Laboratory. The instrumentation for this
method is an active area of development, and includes methods to increase dose to the samples
while implementing high-throughput sample delivery methods.

Conclusion:
Improving instrumentation to irradiate biological samples in real time using a sample
droplet generator and inline fluorescence monitoring to rapidly determine dose response curves for
samples will significantly increase the range of biological problems that can be investigated using
synchrotron hydroxyl radical footprinting.
Development of Robust Partial Least Squares Regression Model for Spectroscopic Determination of Diclofenac Sodium in Environmental Samples
Authors: Mahanty Biswanath , John Angel P. 
Published: November 2018

Background:
Diclofenac (DCF) is an important widely used non-steroidal antiinflammatory
drug. Disposal of expired formulation, excretion from administered dose, the poor performance
of sewage treatment process, contributes to its frequent detection in environment. Analysis
of DCF in environmental sample requires time consuming pretreatment, extraction steps. Though,
UV absorption analysis of DCF is simple but spectral interference of soil organic matter is a problem.
The aim of this paper is to establish appropriate partial least square chemometric model for DCF
quantitation through variable selection, and validation of analytical method through multivariate figure
of merit analysis.

Methods:
Spectral data of DCF spiked soil solution is recorded and variants of partial least squares
(PLS) regression viz., backward-interval PLS (biPLS), synergy-interval PLS (siPLS) and genetic algorithm
(GA) based PLS models (GA-PLS) are developed from autoscaled and 2nd order differential
spectrum. Prediction fidelity of the selected models was evaluated from a blind-folded semi-synthetic
spectral data. The method was validated through figures of merit estimates, such as selectivity, analytical
sensitivity, limits of detection and quantitation.

Results:
The siPLS model developed offered the minimum root mean square error of crossvalidation
(RMSECV) of 0.1896 mg/l and 0.1910 mg/l for autoscaled data (9 variables) and derivative
spectra (12 variables), respectively. Refinement of the derivative spectrum with GA offered a
simplified model (RMSECV:0.1712, 10 variable).

Conclusion:
The GA based variable selection for PLS regression analysis offers robust analytical
tool for DCF in environmental samples. Further research is warranted to model variable interference
in spectral data unknown to analyst in priori.
Cytarabine and Ferric Carboxymaltose (Fe+3) Increase Oxidative Damage and Alter Serotonergic Metabolism in Brain
Authors: Guzmán David Calderón , Brizuela Norma Osnaya , Herrera Maribel Ortíz , Olguín Hugo Juárez , Peraza Armando Valenzuela , García Ernestina Hernández , Jiménez Francisca Trujillo , Mejía Gerardo Barragán 
Published: November 2018

Background & Objective: The purpose of this study was to measure the effect on brain biomarkers after treatment with anticancer compounds - cytarabine (CT) and ferric carboxymaltose (FC) (Fe+3) in Wistar rats.Methods:The Wistar rats were treated as follows: group 1 (control), NaCl 0.9%; group 2, CT (25 mg/k), group 3, FC(Fe+3) (50 mg/k) and group 4, CT + FC(Fe+3). The animals were sacrificed and their brains were obtained and used to measure lipoperoxidation (TBARS), H2O2, Na+, K+ ATPase, glutathione (GSH), serotonin metabolite (5-HIAA) and dopamine. The results indicated an enhancement of lipid peroxidation in the cortex and striatum of groups treated with FC(Fe+3) and CT, while GSH decreased in the cortex of group treated with CT + FC(Fe+3). Dopamine decreased in the cortex of the rats that received CT, while in the striatum, 5HIAA increased in all groups. </P><P> Results & Conclusion: These results suggest that the treatment with CT and FC(Fe+3) boosted oxidative stress and led to an alteration in momoamine concentrations in the brain.
Prevalence of Extended-Spectrum β-Lactamases in Multi-drug ResistantPseudomonas aeruginosafrom Diabetic Foot Patients
Authors: ul Hassan Faaiz , Qudus Muhammad Suhaib , Sehgal Sheikh Arslan , Ahmed Jawad , Khan Momin , ul Haq Khayam , Mumtaz Shahina , Arshad Muhammad , Siraj Sami 
Published: November 2018

Introduction:Pseudomonas aeruginosa is one of the major pathogens associated with the acute tissue damage in patients having Diabetic Foot Ulcer (DFU). The treatment of such infections can be an uphill battle due to the serious resistance to all the mainstay antibiotics, owing to overzealous production of Extended-Spectrum Beta-Lactamases (ESBLs). Pakistan also has a high prevalence of diabetes and complications related to it, however genetic disposition of the pathogens remains underinvestigated.Aim:The main objective of the study was to determine the frequency of ESBLs in Multi-drug resistant P. aeruginosa from diabetic foot patients.Methods:The duration of the present study was one year and 100 patients having DFU were enrolled. All the pus samples were subjected to the bacterial culture, gram staining, catalase test, oxidase test and antimicrobial susceptibility pattern to various antibiotics for the confirmation of P. aeruginosa. Of 23 positive isolates of P. aeruginosa, 10 were ESBLs positive as detected by double disk diffusion test. The positive ESBL strain shows an increase of ≥5mm in the zone of inhibition of the combination discs in comparison to the alone ceftazidime disc.Results:The ESBLs positive strains were also tested for TEM-1, SHV-1, PER-1, and VEB-1, where: (07/10) strains carried SHV-1, (05/10) strains were positive for TEM-1, while none of the isolates were PCR-positive for PER-1 and VEB-1.Conclusion:The findings of the current study show a difference in the pattern of ESBL genes compared to that of other such endeavors. The present study also warrants the PCR-based detection of the type of ESBL as a potential factor to consider in deciding the therapeutic strategy at any point during the treatment.
Effect of Oil Paint Addition on Impact Strength of the Scleral Part of the Acrylic Ocular Prosthesis
Authors: Kati Firas Abd 
Published: November 2018

Background:
For many dental and facial restorations, acrylic resins are the materials of choice because of their appropriate physical and mechanical properties. When making the ocular prosthesis from such materials, it is essential to add the perfect shade in order to match the colour of normal eye. This, however, might have a significant effect on the mechanical properties of acrylic resins.

Objective:
The purpose of this study was to assess the effect of adding the white oil paint (titanium dioxide) to clear acrylic resins on their impact strength.

Methods:
20 samples were constructed from heat cured acrylic resins, and divided into two groups (control and experimental) and each group had 10 samples. The first group was made from clear acrylic resin without the addition of white oil paints, and the second group (experimental) comprised the addition of 1 ml of the white oil paints to acrylic samples. Such samples were prepared with dimensions of (80 mm X10 mm X4 mm) length, width, and thickness, respectively. All the samples were tested by the Charpy's impact strength test. They were exposed to the load till the fracture occurred. All the values were analyzed using SPSS version 20, and the independent T-test was used for comparison between the 2 groups.

Results:
A statistically significant decrease (P-value < 0.001) was found in the impact strength of acrylic resins after the addition of titanium dioxide oil paints (experimental group: 5.97 + 1.11, control group: 9.42+1.32 KJ/M2).

Conclusion:
This study concluded that the addition of titanium dioxide oil paint significantly reduces the impact of strength of the acrylic resin. It is suggested to use different stains which will have no negative effect on impact strength of the acrylic resin.
Effect of Denture Adhesives in New Complete Dentures During a Function
Authors: Guimarães Diego Mourão , Marques Érika Justo , Almagro Giulia Cristina Deiró , Iegami Carolina Mayumi , Stegun Roberto Chaib , Mukai Marcio Katsuyoshi 
Published: November 2018

Background:Denture adhesives are often a matter of controversy. Patients seem to easily accept the use of denture adhesives, while professionals are more hesitant.Objective:The purpose of this study was to evaluate the self-perception, bite force and masticatory efficiency of complete denture wearers with denture adhesives.Methods:Fifteen complete denture wearers had their bite force measured by a gnathodynamometer in the molar region. Subjects also masticated 12 tablets of a chewable artificial test material for 35 masticatory cycles. The test material was washed, dried, sieved and weighed. Both tests were taken with and without the denture adhesive (Corega Ultra). The questionnaire Geriatric Oral Health Assessment Index (GOHAI) was applied to evaluate self-perception with dentures.Results and Conclusion:Masticatory efficiency and bite force for the control group (without denture adhesive) and for the group with denture adhesive presented no statistically significant differences (p= 0.2080 andp= 0.2489, respectively). Self-perception according to the GOHAI index was great for 13% of participants, 40% considered it regular and 47% evaluated it as bad. Within the limitations of this study, it can be concluded that the use of denture adhesive did not promote an improvement in bite force and masticatory efficiency. According to the GOHAI index, self-perception of the participants was classified as bad.
A Comparative Study of Root Coverage using OrACELL™ Versus Subepithelial Connective Tissue Graft: A Randomized Controlled Trial
Authors: Vreeburg Sean K. , Griffiths Garth R. , Rossmann Jeffrey A. 
Published: November 2018

Background:Gingival recession is defined as a mucogingival deformity that includes the apical displacement of the marginal soft tissues below the cemento-enamel junction, loss of attached gingiva, and exposure of root surfaces. The present study aims to compare root coverage outcomes between autogenous Connective Tissue Graft (CTG) and decellularized human dermis (OrACELL™) in areas of facial gingival recession.Methods:Twenty-four non-smoking, healthy patients, with 2mm or greater facial gingival recession at a minimum of one site that is classified as Miller Class I, II, or III recession defects were included. Patients were randomly assigned to either control (CTG) or OrACELL™ (test) groups, which were treated with identical surgical techniques. All root coverage clinical parameters were evaluated at baseline, 3, and 6-months.Results:Eleven patients received CTG while 13 patients received OrACELL™; 23 of the 24 total patients had Miller Class III defects. Baseline mean Vertical Recession (VR) (CTG = 3.27±0.68 mm, OrACELL™ = 3.50±0.89 mm) and Clinical Attachment Level (CAL) (CTG = 4.86±0.74 mm, OrACELL™ = 4.73±0.90 mm) showed no significant difference between groups. At 6 months, mean VR (CTG = 0.59±0.70 mm, OrACELL™ = 1.19±1.07 mm) significantly decreased in both groups, whereas CAL (CTG = 1.90±1.00 mm, OrACELL™ = 2.42±1.17 mm) significantly increased in both groups. Differences between group means were not statistically significant.Conclusion:VR and CAL improved significantly in both the CTG and OrACELL™ groups from baseline to 6 months post-operatively, with no significant differences between groups regarding VR or CAL over the course of the study. In Miller Class III recession defects, OrACELL™ provided a viable alternative to CTG with similar results.
Jornalismo e modelos de mulher: a construção de sentidos das narradoras de TPM
Authors: Rocha Patrícia , Benetti Marcia 
Published: November 2018

A imprensa feminina atua na construção de modelos de mulher a partir de uma fala hegemonicamente normativa e pedagógica. Lançada em 2001, a revista Trip para Mulher, a TPM, caracterizada por narradoras que assumem sua presença no texto e compartilham sua intimidade, afirma constituir-se como uma ruptura aos manuais que ensinam como ser mulher e reiteram estereótipos historicamente construidos. Este artigo busca confrontar essa proposta de ruptura a partir da análise dos sentidos produzidos sobre si mesmas pelas narradoras da revista. A partir da análise de discurso, verificamos que as narradoras constroem imagens de mulher a partir de seis formações discursivas - "mulherzinha", "fora do padrão", "sábia e experiente", "dona do próprio destino", "solteira orgulhosa" e "repórter aventureira". As conclusões indicam que, embora
TPM promova certas rupturas, converte estas formas de suposta resistência em novos modos de regrar a feminilidade.
Edney Silvestre
Authors: Pena Felipe 
Published: November 2018

"Os escritores sentem a obrigação de serem experimentais.
ISSO é muito chato. Só os acadêmicos têm paciência
de ler. O sujeito fica preocupado com a linguagem e esquece
de contar uma história."
"Aqui no programa não há nenhum preconceito. Acho
que os escritores elevem batalhar para ter a obra divulgada."
Jornalismo e literatura: hibridismos culturais no comentário
Authors: Ferreira Junior José , Rocha Larissa Leda 
Published: November 2018

O jornalismo contemporâneo, especialmente o opinativo,
apresenta-se hoje Como um lugar privilegiado para o empréstimo, trocas doações entre a literatura e o jornalismo. A narrativa híbrida, que vem daí, propõe que se tire os trajes formais do jornalismo opinativo editorial ista ou mesmo das matérias diárias, para vestir a transformação modo mais informal,
trazendo pessoalidade e sensibilidade. Trata-se de uma hibridização de fronteiras. Discutindo ainda a questão cm torno do real no jornalismo e novos
formatos de produção textual, este trabalho traz conto objeto de análise o gênero de comentário, exemplificado na obra do jornalista Josias de Souza e a fase Concreta do poeta Haroldo de Campos.
Jornalismo literário e cultural: Perspectiva histórica
Authors: Strelow Aline 
Published: November 2018

Este trabalho tem como objetivo traçar um breve histórico do jornalismo literário e cultural, desde o surgimento da crítica literária, na França, em 1665, até os dias de hoje,
no Brasil. Através do método histórico e do diálogo com diferentes autores que abordaram o tema, pretendemos apresentar um panorama que pode servir como ponto de
partida para os pesquisadores interessados em estudar o assunto.
Ao longo do percurso do texto, são discutidas as relações entre as peculiaridades que caracterizam estas especializações do jornalismo, em diferentes épocas, e o contexto histórico no qual estão inseridas. A linha histórica permite compreendermos as
motivações das mudanças que se estabelecem neste campo, assim como as possíveis.
A sobrevida do fait divers
Authors: Vogel Daisi 
Published: November 2018

Histórias suspensas entre o racional e o desconhecido, sínteses narrativas do estranho, do "espanto fundamental''. A partir de textos selecionados em revistas de duas épocas, Senhor (1959) e piaui (2006), cujasmpublicações se distanciam, portanto, quase 50 anos, procura-se pensar sobre
a agência cultural dessa sorte de rela os jornalísticos que, em fronteira livre com a literatura, possuem a característica da informação total: são compreensíveis em si mesmos, têm autonomia de significado e uma curiosa permanência no tempo. Qual a atualidade do fait divers? Quais questões estéticas ele suscita, em termos culturais? Que lugar ocupa, ainda hoje, na ficção social que a mídia torna dominante?
Razão-Poesia: comunicação, poesia e pensamento
Authors: Dravet Florence , Castro Gustavo de 
Published: November 2018

Na transmissão da informação, na sedução para vencia, na persuasão ideológica e no entretenimento, os discursos midiáticos valem-se, entre outros elementos comunicativos, de recursos poéticos. Mas não é somente aí que se verifica a interação entre Comunicação e Poesia, esta incide também
na construção dos saberes. Nesta perspectiva, a Razão-Poesia se apresenta como um caminho de teorização para a Comunicação, desde que se conceba três possibilidades ele interação no pensamento: a possibilidade do diálogo
entre a razão - no sentido do logos heraclitiano - e a poesia formal; a possibilidade da dialogia entres os saberes de uma poesia que não se restringe ao domínio do demeus; e, por fim, a possibilidade de uma teorização que não se recuse a conduzir suas buscas seguindo os caminhos apontados por
noções poéticas, inauguradas na poesia, tal como o Principio com, o Aberto e a Transparência.
Dilema e experimentação em João do Rio: contribuições ao jornalismo e à literatura
Authors: Jorge Thais de Mendonça , Borges Rogério Pereira 
Published: November 2018

Este trabalho pretende demonstrar que a invençào do jornalismo e a expansão da literatura no Brasil são fenômenos que têm no nascedouro aspectos comuns: a) movimentos artísticos, literários e jornalísticos em escala mundial na virada do século XIX para o XX; b) eclosão de novos gêneros na literatura e no jornalismo, realçando figuras como a de João do
Rio, uma figura que se Situa entre o escritor e o jornalista; e e) afirmação do texto noticioso como bem simbólico numa sociedade em transformação.
É grande a quantidade de escritores que mantiveram carreira jornalística.
Hemingway e Orwell; Dostoievski, Tchekov, Balzac, Vargas Llosa, Garcia Márquez são nomes de vulto da literatura universal que mantiveram vínculos com a imprensa. No Brasil, não foi diferente, com Machado de Assis, José de Alencar, Olavo Bilac e Castro Alves. João Paulo Alberto Coelho Barreto se situou na fronteira entre a ficção e a realidade e inaugurou a reportagem e a crônica no Brasil.
Genealogia e identidades autobiográficas: os casos de Um passaporte húngaro e Los rubios
Authors: Gleghorn Charlotte 
Published: November 2018

Este texto problematiza a questão da identidade em dois documentários recentes
realizados no Brasil e na Argentina, Um passaporte húngaro (Sandra Kogut, 2001)
e Los rubios (Albertina Carri, 2003). Ambos os filmes foram realizados por mulheres, e,
sendo altamente subjetivos, são de certa maneira autobiográficos. Deste modo, suscitam
uma discussão sobre o papel do diretor na construção da narrativa, quando este se torna
protagonista do seu próprio filme, mostrando assim, explicitamente, a sua corporalidade
na tela de cinema. Intrínsecas a esta discussão são a questão do corpo e a da consciência
de si mesmo do diretor, enquanto preocupações centrais dos filmes de Kogut e Carri. Ao
estabelecer uma comparação entre Uni passaporte húngaro e Los rubios, este artigo pretende
mostrar diferentes perspectivas sobre a autobiografia no celulóide que, muitas vezes,se vêem ignoradas.