bluuebunny/crossref_metadata_2025_split huggingface dataset:
La política de inclusión social, valoración y servicios ambientales del reciclaje en Bogotá
Authors: Tarupi - Montenegro Edisson Armando , De La Fuente De Val Gonzalo 
Published: August 2019

Introducción: Las interrelaciones e interdependencia que se desarrolla en un espacio urbano desde el punto de vista de un ecosistema social y ecológico requieren de la acción conjunta y planificada en atención a las políticas públicas. Metodología: La valoración económica ambiental requiere, en primer lugar, de una metodología exploratoria para establecer las preferencias de los hogares, empresas y sociedad por conservar los servicios ambientales del reciclaje y, desde este punto de vista, se hace una descripción de la población o los hogares que serán elegidos aleatoriamente en toda la ciudad de Bogotá, asimismo, se utiliza un modelo Logit para determinar la “disponibilidad a pagar” (DAP). Resultados: La metodología de valoración contingente permite estimar el valor monetario que la población le da al reciclaje. Lo cual permite estimar la disponibilidad a pagar – DAP- por lo servicios ambientales del reciclaje, mediante un modelo Logit, teniendo en cuenta variables sociales y económicas.Conclusiones: Agregando la DAP promedio estimada, con todos los hogares en Bogotá, se recaudarían 2.395.244.880 millones de pesos, los cuales constituyen una inversión que se traduce en mejor ingreso para los recicladores en favor de la calidad de vida sostenible.
Peningkatan Hasil Belajar Siswa Kelas I Madrasah Ibtidaiyah Negeri 6 Tapin melalui Model Pembelajaran Kooperatif Tipe Make A Match
Authors: Rismarini Rismarini 
Published: August 2019

Pembelajaran tematik dalam Kurikulum 2013 harus didesain semenarik mungkin dan sedekat mungkin dengan lingkungan siswa untuk menciptakan suasana yang menyenangkan sehingga dapat membangkitkan semangat siswa dalam menggali informasi dari materi yang akan dipelajari. Pembelajaran direncanakan sedemikian rupa agar siswa dapat menemukan konsep sendiri berdasarkan pengetahuan awal sehingga akan lebih bermakna. Hal ini didukung oleh pendapat dari Trianto yang menjelaskan bahwa proses pembelajaran yang aktif, kreatif, inovatif, efektif, dan menyenangkan dapat dilakukan oleh siswa yang disiapkan oleh pendidik melalui kegiatan-kegiatan yang menarik, menyenangkan untuk membangkitkan rasa ingin tahu, memotivasi siswa untuk berpikir kritis, dan menemukan hal-hal baru.Aktivitas guru kelas pada pertemuan 1 siklus I sebesar 68,8% pada pertemuan 2 siklus 1. Setelah siklus 2 mengalami peningkatan dari 77,1% pada pertemuan 1 menjadi 89,6% pada pertemuan kedua (siklus 2). Aktivitas siswa pada siklus I didominasi cukup aktif (pertemuan 1 didominasi cukup aktif dengan nilai 68,64% dan pertemuan ke 2 menjadi 72,72%. Pada siklus II meningkat yaitu dari mayoritas cukup aktif mulai meningkat ke aktivitas aktif (Siklus II pertemuan 1) sebesar 27,28% dan cukup aktif 52,54% dan pada pertemuan ke 2 didominasi aktivitas sangat aktif sebesar 63,63% dan yang cukup aktif 31,82% (secara keseluruhan dari aktif dikategorikan sangat aktif). Hasil belajar dengan ketuntasan klasikal siklus I pertemuan pertama sebesar 63,63%, pertemuan kedua 68,18%, siklus II pertemuan pertama sebesar 77,27% dan pertemuan kedua 95,45%.
TRACING THE CONCEPT OF POLITICAL LEADERSHIP OF ISLAM NUSANTARA
Authors: Faddad Zaki 
Published: August 2019

Certain community both based ethnicities and nationalities have different characteristics on the notion of political leadership. Studies on the political leadership concept in Indonesia cannot escape from the Javanese political leadership characteristics. The reason is simply, because most of Indonesian leaders are from Java. Ben Anderson (1990) sees the Sukarno and Suharto leadership as the representation of Islamic Mataram Kingdom that was absolute and totalitarian typical leadership. Then, it follows cultural stereotyping of political leadership based on ethnicity in Indonesia. Jajat Burhanuddin (2014) sees that Melayu has democratic political culture, while Jawa has authoritarian political culture based on the creed “Manunggaling Kawula Gusti” –Unity between God-ruler or Subject-ruler. However Burhanuddin (2014) does not explain the nature of the creed in Javanese typical political leadership. Naim (2014) controversially sees that there are bipolar characteristics of political leadership in Indonesia. Jawa has absolute and totalitarian typical leadership that is influenced by Javanese local belief; otherwise Melayu (Outside Jawa) has egalitarian and democratic political leadership that is strong influenced by Islamic teaching. This paper tries to dig the understanding of principles on political leadership in Indonesia by making comparison both Jawa and Melayu on the nature of political leadership. The paper engages Talal Asad (2009) conceptual frameworks on discursive tradition. Thus from Asad point of view political leadership is the result of a dynamic process between agency and structure. That is a process of negotiation between the ruler and subjects in a certain structure.
Contemporary Development in Floating Oral In-Situ Gel: A Review
Authors: Ramesh Pareek  , Pawan Kumar Sharma  , Vandana Sharma  
Published: August 2019

Conventional oral dosage forms having low bioavailability problems due to their rapid gastric transition from stomach, in case of drugs which are less soluble at alkaline pH of intestine. Further drugs which produce their nearby activity in stomach, get quickly emptied don't get enough residence time in stomach. To avoid these problems, different endeavors have been made to draw out the the retention time of drug in stomach. The development of in situ gel systems has gotten impressive consideration in the course of recent years as it gives the most ideal approach to conquer problems of immediate release and short GI residence of fluids. In situ gel forming drug delivery systems are principle, capable of releasing drug in a sustained manner maintaining relatively constant plasma profiles. The in situ gel dosage form is a liquid before administration and after it interacts with gastric contents gets changed over to gel which floats on gastric contents. In situ gel formation happens because of one or combination of various stimuli like pH change, temperature modulation and ionic crosslinking. This accomplishes expanded residence as well as sustained release. It can be easily applied to the site of drug absorption where they swell to form a strong gel that is capable of prolonging the residence time of the active substance. This review gives a short thought regarding floating oral in situ gel formation and research done by different researchers on various drugs.
Tıp fakültesi ve meslek yüksekokulu öğrencilerinde sağlıklı yaşam biçimi davranışları ve etkileyen faktörler
Authors: SERT Abdullah 
Published: August 2019

Amaç: Bu çalışmada Yüzüncü Yıl
Üniversitesi Tıp Fakültesi ve Van Meslek Yüksek Okulu’nda eğitim gören
öğrencilerin sağlıklı yaşam biçimi davranışlarının değerlendirilmesi ve bu
davranışlarla ilişkili sosyo-demografik özelliklerin saptanması amaçlanmıştır. Yöntem: Çalışmanın evreni Yüzüncü Yıl
Üniversitesi Tıp Fakültesi ve Van Meslek Yüksek Okulu’nda eğitim gören 1842
öğrenci oluşturmaktadır. Tabakalı ve sistematik yöntemle seçilen 470 öğrenci
örnek grubunu oluşturmaktadır. Verilerin toplanmasında öğrencilerin sosyo-demografik
özelliklerini ve sağlıklarıyla ilgili bazı konuları sorgulayan bir anket ile
Sağlıklı Yaşam Biçimi Davranışları-II (SYBD-II) ölçeği gözetim altında
uygulanmıştır. Bulgular: Öğrencilerin 313’ü (%66.6)
Meslek Yüksekokulu’nda, 157’si (%33.4) Tıp Fakültesinde öğrenim görmektedir.
Araştırmaya katılan öğrencilerin 199’u (%42.6) kız, 268’i (%57.4) erkektir.
Öğrencilerin yaşlarının ortanca değeri 22’dir (en küçük-en büyük=17-60).
Öğrencilerin sağlıklı yaşam biçimi davranışları ölçeğinden aldıkları puanın
ortalaması 123.2±20.6’dir. Fakülteler arasında SYBD toplam puanı açısından
istatistik olarak anlamlı fark bulunmamıştır (p=0.05). Sonuç: Öğrencilerin SYBD toplam
puanı ortalaması orta düzeyde bulunmuştur. SYBD düzeyinin artırılması için
farkındalık yaratma ve bilinçlendirme çalışmaları yapılmalıdır.
Enhanced Mechanical-Integrity Characterization of Oilwell Annular Sealants Under In-Situ Downhole Conditions
Authors: Jimenez Walmy Cuello , Darbe Robert , Pang Xueyu 
Published: August 2019

Summary
In this study, we describe an innovative and novel methodology comprising a high–pressure/high–temperature (HP/HT) in–situ–triaxial–testing apparatus for the measurement of sealant mechanical properties (i.e., compressive strength, Young's modulus, and tensile strength) under simulated downhole conditions. The equipment can be used to perform both curing and testing using the same apparatus, thus eliminating depressurization and cooling of test specimens. Additionally, at minimum, three samples can be tested sequentially for statistical analysis and uncertainty mitigation, along with performing real–time monitoring of total HP/HT shrinkage/expansion. The testing apparatus is rated to 30,000 psi for axial loading, 20,000 psi for confining loading, and 400°F. Preliminary validation of Young's modulus was performed with five different plastic samples, yielding error percentages of less than 5% compared to measurements performed using a standardized loading frame. Compressive– and tensile–strength validations were performed using a 16–lbm/gal cement design, and error percentages of less than 2.5 and 7%, respectively, were obtained compared to standardized testing procedures or other studies of the subject. Moreover, a 16–lbm/gal cement system was also used to help assess the functionality of the testing apparatus under simulated wellbore conditions with temperature and pressure ranging from 80 to 350°F and 3,000 to 8,000 psi, respectively.
Intention to use Maternity Waiting Home and determinant factors among pregnant women in Misrak Badewacho District, Hadiya Zone, Southern Ethiopia: A cross sectional study
Authors: Obola Teshale Dojamo , Leimengo Tekleab Yohannes , Herut Berhan Meshesha , Kebede Deresse Legesse 
Published: August 2019

Abstract
Background: -

Maternity waiting homes (MWHs) are residential facilities located near a health facility to accommodate women in their final weeks of pregnancy to bridge the geographic gap in obstetric care between rural and urban areas and areas with poor access to a facility. The world health organization adopted it as one component of a comprehensive package to prevent maternal morbidity and mortality. Yet, there is a shortage of information on the magnitude of intention and utilization of MWH among pregnant women in the study area. The purpose of the study was to assess intention to use MWH and associated factors among pregnant women.
Treating periodontitis-A systematic review and meta-analysis comparing ultrasonic and subgingival hand scaling at different pocket probing depths.
Authors: Zhang Xin , Hu Zixuan , Zhu Xuesong , Chen Jun , Li Wenjie 
Published: August 2019

Abstract
Background: Mechanical plaque removal has been commonly accepted to be the basis for periodontitis treatment. The study aims to compare the effectiveness of ultrasonic subgingival scaling and subgingival hand scaling at different initial pocket probing depths in periodontitis treatment. Methods: Public databases were searched. Weighted mean pocket probing depths and clinical attachment loss reduction differences estimated by random effects model. Results: Ten randomized controlled trials were included out of 1,434 identified. Selected outcomes were pocket probing depth and clinical attachment loss. Initial pocket probing depth and follow-up periods formed subgroups. For 3-month follow-up: (1) too few shallow initial pocket studies available; (2) medium depth studies were unmergeable; (3) deep studies were adequate. No statistical differences between pocket probing depth nor clinical attachment loss reduction between ultrasound and hand groups. For 6-month follow-up: (1) too few shallow initial pocket probing depth studies for analysis; (2) medium initial pocket probing depth studies favored hand scaling. No statistical differences observed in clinical attachment loss reduction between the two approaches; (3) deep initial pocket probing depth studies showed hand scaling superior by both measures. Conclusion: When initial pocket probing depths were ≥4mm, pocket probing depth results, clinical attachment loss reduction, and other outcomes indicated subgingival hand scaling was superior. When operation duration and comfort were considered, ultrasonic debridement was.
Predisposing factors influencing occupational injury among frontline building construction workers in Ghana
Authors: Amissah John , Badu Eric , Agyei-Baffour Peter , Nakua Emmanuel Kwaku , Mensah Isaac 
Published: August 2019

Abstract
Objective
This study aims to examine the predisposing factors influencing occupational injuries among frontline construction workers in Ghana. A cross-sectional survey was carried out with 634 frontline construction workers in Kumasi metropolis of Ghana using a structured questionnaire. The study was conducted from December 2016 to June 2017 using a household-based approach. The respondent were selected through a two-staged sampling approach. A multivariate logistics regression model was employed to examine the association between risk factors and injury. Data was analyzed employing descriptive and inferential statistics with STATA version 14.

Results
The study found an injury prevalence of 57.91% among the workers. Open Wounds (37.29%) and fractures (6.78%) were the common and least injuries recorded respectively. The distal factors (eg. Age, sex of worker, income) and proximal factors (eg. work structure, trade specialization, working hours, job/task location, and monthly off days were risk factors for occupational injuries among frontline construction workers. The study recommends that policy makers and occupational health expert should incorporate the proximal and distal factors in the design of injury prevention as well as management strategies.
A fast and simple protocol for synthesizing effective antimicrobial silver nanoparticles in non-specialized facilities
Authors: Vazquez-Munoz Roberto , Arellano-Jimenez M. Josefina , Lopez-Ribot Jose L. 
Published: August 2019

Abstract
Objective

Silver nanoparticles (AgNPs) can be difficult or expensive to obtain or synthesize for laboratories in resource-limited facilities. The purpose of this work was to create a fast, facile, and cost-effective method for synthesizing AgNPs with potent antimicrobial properties, that can be readily implemented in non-specialized laboratories.Results

Our developed method uses a rather simple and rapid chemical reduction process that involves the addition of a polyvinylpyrrolidone solution to a warmed silver nitrate solution under constant vigorous stirring, immediately followed by the addition of sodium borohydride with constant stirring for an additional 15 minutes. AgNPs had an aspect ratio close to 1, with an average size of 6.18 ± 5 nm. AgNPs displayed potent antimicrobial activity, with Minimal Inhibitory Concentration values of 3 µg mL-1 and 1.5 µg mL-1 for Staphylococcus aureus and Candida albicans respectively.Keywords :

Silver nanoparticles, nanoantibiotics, synthesis method, AgNPs, metallic nanoparticles
Human plasma dynamically quenches the fluorescein at the initial point of Oxygen Radical Absorption Capacity (ORAC) Assay
Authors: Gunawardena Harshi Prasadini , Silva Renuka , Ranasinghe Pathmasiri 
Published: August 2019

Abstract
Objective: Oxygen Radical Absorbance Capacity (ORAC) assay measures the quenching of fluorescent probe by peroxyl radicals. Antioxidants present in biological systems block the quenching of fluorescence probe. We experienced the dynamic quenching of fluorescein, the fluorescence probe used in ORAC assay by human plasma while the plasma ORAC assay was optimized. Therefore, for the first time, we report the quenching of fluorescein by human plasma at the initial point of ORAC assay. Results: Aqueous whole and non-protein fractions of plasma were used in the analysis. Since both fractions showed a similar pattern of quenching at the initial stage, quenched percentage of fluorescein was calculated and added to each sample in subsequent analysis. Addition of extra 20% fluorescein allowed plasma samples to quench the required amount of fluorescein and follow the normal decay curves afterwards. Further, change of fluorescein quenching (ΔF/F0) disclosed a dose dependent linear relationship with plasma (R2=0.8). Conclusion: It can be speculated that dynamic quenching exhibited by human plasma biomolecule/s at the initial stage would be of non-protein aqueous phase molecule/s. We suggest initiating further studies to detect, identify and quantify the fluorescein quenching biomolecules present in human plasma for further improvements in plasma ORAC assay.
Instant analgesic effect of radial extracorporeal shock wave therapy on primary dysmenorrhoea according to functional magnetic resonance imaging: Study protocol for a randomised placebo-controlled trial
Authors: Liu Shanshan , Wang Lezheng , Yang Jian 
Published: August 2019

Abstract
Background: Primary dysmenorrhoea (PDM) is defined as a series of pain-dominated symptoms during and after menstruation without organic lesions. Non-steroidal anti-inflammatory drugs and oral contraceptives are usually recommended as first-line drugs for the clinical treatment of PDM, but their widespread long-term application is controversial. Radial extracorporeal shock wave therapy (rESWT) has been widely applied in musculoskeletal rehabilitation because of its secure and non-invasive characteristics and its confirmed effect in improving pain symptoms. This research seeks to explore the efficacy of rESWT for PDM and the changes in brain function of patients with PDM. Methods: This clinical research will be a randomised, evaluated blind and sham-controlled trial. Forty-six patients with PDM will be divided into the rESWT group (n = 23) and the sham rESWT group (n = 23) at random. In the rESWT group, treatment will be applied once within 48 hours of menstruation at six abdominal myofascial trigger points. The sham rESWT group will receive sham shockwave therapy on the same sites but without energy input. Other dysmenorrhoea-related treatments in both groups will be limited. The main indicators include the short-form McGill Pain Questionnaire and the Cox Menstrual Symptom Scale. The secondary indicators include the Zung Self-rating Anxiety Scale and Self-rating Depression Scale and functional magnetic resonance imaging (fMRI) changes in brain regions. Results will be evaluated at the screening, baseline and before and after treatment, and adverse treatments will be examined. Inter- and intra-group analyses will be performed in the statistics section. Discussion: This randomised controlled study is designed to explore the immediate efficacy of rESWT for PDM. After rESWT treatment, PDM symptom tests, pain tests as well as fMRI data will be investigated for the potential connections between immediate neuroanalgesic mechanisms, which are associated with pain and brain networks. The main results will be used to assess the efficacy of rESWT, and secondary results will focus on improving the neurobiological understanding of disease treatment.
Efficacy and safety of Guhong injection for treating the Coronary microvascular disease: study protocol for a randomized controlled trial
Authors: Zhuang Jieqin , Liu Shuling , Cai Hairong , Dai Xingzhen , Chen Yanhong , Jin Zilin , Chen Bojun 
Published: August 2019

Abstract
Background: Coronary microvascular disease (CMVD) refers to cardiovascular diseases with normal coronary angiography but evidence of myocardial ischemia or microcirculation lesions, often presenting as angina pectoris attack. Coronary artery of microtubules dysfunction is one of the pathogenesis of coronary heart disease,but the occurrence and development and the current of CMVD intervention therapy remains to be further researched.Chinese traditional medicine (TCM)has advantages in the treatment of cardiovascular diseases, therefore, this article describes an ongoing randomized controlled clinical trial, based on the theory of TCM, for the purpose of evaluating the efficacy and safety of Guhong injection ,a Chinese patent medicine,compared with placebo in patients suffering from CMVD. Methods/design: This is a multicenter, randomized, parallel arm, open-label, double-blind, placebo-controlled clinical trial. A total of 260 eligible patients will be allocated and randomly assigned, in a ratio of 1:1, to either the experimental group or the control group. The treatment course is 10 consecutive days, with a 8-week follow-up. The primary outcome is the frequency of angina attacks, Secondary outcomes include myocardial metabolites, ecg changes, quantitative score of TCM syndromes, inflammatory response and endothelial function indicators. Discussion: This trial is strictly designed in accordance with principles and regulations issued by the China Food and Drug Administration (CFDA). The results will provide high quality evidence on the efficacy and safety of Guhong injection in the treatment of CMVD. Trial registration: Chinese Clinical Trials Registry, ChiCTR1900022902. Registered on 27 April 2019.
Integrated Genomic Analysis Revealed Associated Genes for Alzheimer’s Disease in APOE4 Non-Carriers
Authors: Jiang Shan , Zhang Chun-Yun , Tang Ling , Zhao Lan-Xue , Chen Hong-Zhuan , Qiu Yu 
Published: August 2019

Background:APOE4 is the strongest genetic risk factor for late-onset Alzheimer’s disease (LOAD). LOAD patients carrying or not carrying APOE4 manifest distinct clinico-pathological characteristics. APOE4 has been shown to play a critical role in the pathogenesis of AD by affecting various aspects of pathological processes. However, the pathogenesis involved in LOAD not-carrying APOE4 remains elusive.Objective:We aimed to identify the associated genes involved in LOAD not-carrying APOE4.Methods:An integrated genomic analysis of datasets of genome-wide association study, genome-wide expression profiling and genome-wide linkage scan and protein–protein interaction network construction were applied to identify associated gene clusters in APOE4 non-carriers. The role of one of hub gene of an APOE4 non-carrier-associated gene cluster in tau phosphorylation was studied by knockdown and western blot.Results:We identified 12 gene clusters associated with AD APOE4 non-carriers. The hub genes associated with AD in these clusters were MAPK8, POU2F1, XRCC1, PRKCG, EXOC6, VAMP4, SIRT1, MME, NOS1, ABCA1 and LDLR. The associated genes for APOE4 non-carriers were enriched in hereditary disorder, neurological disease and psychological disorders. Moreover, knockdown of PRKCG to reduce the expression of protein kinase Cγ isoform enhanced tau phosphorylation at Thr181 and Thr231 and the expression of glycogen synthase kinase 3β and cyclin-dependent kinase 5 in the presence of APOE3 but not APOE4.Conclusion:The study provides new insight into the mechanism of distinct pathogenesis of LOAD not carrying APOE4 and prompts the functional exploration of identified genes based on APOE genotypes.