bluuebunny/crossref_metadata_2025_split huggingface dataset:
DRUG UTILIZATION PATTERN FOR SKIN DISEASES IN DERMATOLOGY OPD AT TERTIARY CARE HOSPITAL OF WESTERN MAHARASHTRA
Authors: Vakade Kiran P , Indurkar Vishal A , Chordia Aayush H 
Published: August 2019

Background: Periodic auditing of prescriptions in terms of drug utilization study is an important tool to enhance the efficacy of the treatment, to decrease the risk of the adverse effects, to give cost-effective treatment and to provide useful feedback to the clinician. Prevalence of dermatological diseases is very high throughout the world, and in day to day practice, a quarter of the cases are related to dermatological manifestations. In studies conducted in the Out Patient Department (OPD) of dermatology in North Palestine and Western Nepal, irrationalities in the prescriptions have been reported. Aim: To study the drug utilization pattern for skin diseases in dermatology OPD at tertiary care hospital of Western Maharashtra. Methodology: The retrospective analysis of dermatology OPD records of 6 months (1st March 2018- 31st August 2018) was carried out during the study period (1st September 2018 to 30th November 2018). The proforma for collecting data was designed. Demographic details, diagnosis and treatment are given for each patient were recorded. The data collected was condensed, and the master chart was prepared for data analysis. Result: During the study period, a total of 3869 patient’s case records were studied and analysed. A maximum number of patients (26.5%) found in the age group 31-40 years, followed by 23.5% of patients in the age group 21- 30 years. Fungal infection was found in 39.6 % of patients followed by acne in 14.2% patients and eczema in 9.1% of patients. Drugs most commonly prescribed were antihistaminics (45.02%) followed by antifungal (39.6%) and steroids (27.8%). Levocetirizine (74.07%) and hydroxyzine (16.5%) were the most commonly prescribed antihistaminics. Itraconazole (58.17%) and Griseofulvin (24.67%) were the most commonly used oral antifungal drugs. Miconazole (73.73%) was the most commonly used topical antifungal drug, followed by ketoconazole (12.45%). Among steroids, prednisone (52%) and betamethasone (38.05%) were the most commonly used steroids by oral route while clobetasol (68.09%) and mometasone (19.5%) were the most commonly used steroids by topical route. Our study revealed that the percentage of drugs prescribed by the WHO essential drug list was only 23.87%. Drugs which prescribed by the generic names were less than <1%. Conclusion: Treatment protocols used in the management of skin disorders were near to the standard guidelines.
Keywords: Drug utilization; Prescription pattern; Dermatology; Skin disorders.
Асоціації рівня макрофаг-інгібуючого фактора зі ступенем тривожності та депресії у хворих, що перенесли інфаркт міокарда з елевацією сегмента ST
Authors: Petyunina O. V. , Kopytsya M. P. , Skrynnik О. V. 
Published: August 2019

The aim – to investigate associations between macrophage inhibitory factor (MIF) and anxiety, depression and stress in patients with ST-segment elevation myocardial infarction (STEMI).Materials and methods. 73 patients with STEMI with TIMI-III aged 58.37±10.34 were enrolled in the study. Revascularization tactics distribution was the following: 43 (58.9 %) patients underwent primary percutaneous coronary intervention using bare-metal coronary stent, 30 (41.1 %) – pre-hospital thrombolysis with subsequent percutaneous coronary intervention within12 hours. Echocardiography was done during the period of hospitalization. Serum MIF was studied using the enzyme linked immunoassay method. Anxiety, depression and stress were determined with DASS-21 questionnaire.Results and discussion. When comparing the median values of the MIF level in STEMI patients, a statistically significant increase in the MIF concentration relative to control group (2582.80 [1308.40–4122.20] and 573.75 [397.80–1016.75] ng/ml, p<0.001). It evidences the activation of the formation of MIF after the index event. Positive correlation was determined between the level of MIF, the level of troponin I (r=0.33; р=0.045) and blood leukocytes (r=0.36; р=0.039) that confirms its involvement into inflammation and necrosis processes. The univariant and multivariate analysis revealed the effect of the degree of depression and anxiety growth on the DASS-21 questionnaire (p=0.0138 and p=0.0050, respectively) on the increasing of the MIF.Conclusions. The data obtained confirm the relationship between the MIF and anxiety and depression prior the onset of myocardial infarction, indicating their influence on the processes of inflammation.
OSTEOPIOKILOSIS WITH EPISODIC SYMPTOMS
Authors: Singh Dr. Surjeet , Katoch Dr. Punit 
Published: August 2019

Osteopiokilosis is benign skeletal dysplasia diagnosed incidently as multiple oval sclerotic lesions of bone. We present a case report of 57 years male with episodic pain, swelling and superficial wounds of left knee from past 2 years. Osteopiokilosis have multiple periarticular osteosclerotic lesions which are mostly asymmetrical usually in long tubular bones and hands. To report episodic symptoms in osteopiokilosis and to avoid unnecessary panic of the patient after osteosclerotic lesion.
Keywords: Osteopiokilosis, osteosclerosis
TO EVALUATE THE ROLE OF INTRATHECAL HATG AND ITS COMPARISON WITH INTRAVENOUS AND INTRAMUSCULAR HATG IN TREATMENT OF TETANUS
Authors: Ram Dr. Sita , Bharia Dr. J.P. 
Published: August 2019

Background: Tetanus is a vaccine-preventable disease that continues to occur despite several decades of sustained global health programs. Recently outbreaks of tetanus have been reported after natural disasters such as tsunamis and earthquakes.
Methods: The present study was carried out among 30 patients of tetanus irrespective of age, sex and severity, admitted in P.B.M. Hospital, Bikaner.
Results: Overall mortality was 30% in present study. Out of 10 patients in each group one in group I, 4 in group II and 4 in group III expired respectively. So the mortality was 10% in group I, 40% in group II & III. In mild tetanus mortality was nil in all groups. In moderate tetanus mortality was 9.9%. All patients of moderate tetanus in group I and II survived. In group III mortality in moderate tetanus patients was 20%. In severe tetanus patients over all mortality was 53.3%, in group I 25%, in group II and 50% and in group 10% respectively.
Conclusion- Intrathecal HTAT is safe and effective treatment.
Keywords: Intrathecal, Intravenous, Mortality, HTAT.
REVASCULARISATION OF AN IMMATURE PERMANENT TOOTH USING PLATELET RICH FIBRIN AND BIODENTIN AS A MATRIX - A CASE REPORT
Authors: Tomer Dr. Anil K , Mangat Dr. Panna , Behera Dr. Akankshita , Kour Dr. Savneet , Gupta Dr. Artika , Bhagat Dr. Vasuda , Mittal Dr. Nitish 
Published: August 2019

Any injury to the pulp during its development lead to cessation of dentin formation and root growth. Status of the pulp and root development are the decisive factors in the treatment approach. Various treatment options include surgery with rood end sealing, apexification using calcium hydroxide ,placement of apical plug and regenerative endodontic procedures to induce
apexogenesis. This study describes the treatment of an immature permanent tooth which was treated with regenerative approach using 3% NaOCl and 17% ethylenediaminetetraacetic acid as irrigants,and then medicated with triple antibiotic paste, after that platelet rich fibrin (PRF) and Biodentine were place in the canal. On follow up at 3 ,6,12 months healing of periapical lesion, dentinal thickening, and apical closure were evident. So, PRF can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic procedures.
Keywords: Platelet rich fibrin (PRF), Biodentine, open apex, revascularisation
ENDOSCOPIC EVALUATION OF MANOMETRIC PROFILE OF GASTRO ESOPHAGEAL REFLUX DISEASE
Authors: Gupta Dr. Radhey Shyam 
Published: August 2019

Background: Gastro esophageal reflux disease leads to poor quality of life to patients because of pain and discomfort. Some studies also reported that incidence of adenocarcinoma of esophagus and Barrett's esophagus among patients with reflux disease. The abnormal esophageal motility act as a major risk factors and also reported with severity and prognosis of the disease.
Material & Methods: In present study 50 patients of heart burn or acid regurgitation (GERD) for at least more than 3 months were enrolled from outdoor and from ward by simple random sampling. Clearance from Institutional Ethics Committee was taken before start of study. Written informed consent was taken from each study participant.
Results: 15 (30%) had non-erosive reflux disease and 35 (70%) had erosive reflux disease. Among the patients of non-erosive reflux disease, 13 (26%) had normal lower esophageal sphincter pressure and 2 (4%) had Low Lower esophageal sphincter pressure. Among the patients of erosive reflux disease, 32 (64%) had normal lower esophageal sphincter pressure and 3 (6%) had Low Lower esophageal sphincter pressure (P value >0.05). Among the patients of non-erosive reflux disease, 10 (20%) had normal esophageal motility and 5 (10%) had Ineffective esophageal motility. Among the patients of erosive reflux disease, 25 (50%) had normal esophageal motility and 10 (20%) had Ineffective esophageal motility (P value >0.05).
Conclusion: Low Lower esophageal sphincter and Ineffective or abnormal esophageal motility pressure was non-significantly associated with non-erosive and erosive reflux disease. Ineffective esophageal motility and Low LES pressure was the main cause for gastro esophageal reflux disease
Keywords: GERD, High Resolution Manometry, Ineffective peristalsis.
ASSESSMENT OF LIVER FUNCTION TESTS IN DENGUE FEVER
Authors: Gupta Dr. Radhey Shyam 
Published: August 2019

Background: The prevalence of dengue viral infection has tended to rise globally in the recent decades. In India the burden and prevalence of dengue viral infection is increasing as trends reported globally. Hence, along with global pandemic concern dengue has become major public health concern in India. Dengue is an emerging epidemic disease and several outbreaks among every state of India is being reported from time to time.
Material & Methods: The present cross-sectional study includes 50 Patients who had dengue IgM antibody positive were enrolled from outdoor and from ward by simple random sampling. Clearance from Institutional Ethics Committee was taken before start of study. Written informed consent was taken from each study participant.
Results: 10 (20%) patients had normal serum ALT levels, 13 (26%) patients had serum ALT levels raised less than Two-folds, 12 (24%) patients had serum ALT levels raised more than Two-folds, 11 (22%) patients had serum ALT levels raised more than four-folds and 04 (8%) patients had serum ALT levels raised more than ten folds. Among the total study participants 7 (14%) had normal serum AST levels, 14 (28%) patients had serum AST levels raised less than Two-folds, 14 (28%) patients had serum AST levels raised more than Two-folds, 12 (24%) patients had serum AST levels raised more than four-folds and 03 (6%) patients had serum AST levels raised more than ten folds.
Conclusion: Liver function deterioration in dengue fever was varied from normal range of biochemical markers to raised liver function markers. AST elevation was more statistically significant than ALT. Hyperbilirubinemia and raised alkaline phosphatase levels were reported. Low serum albumin levels were associated with critical phase of the liver disease.
Key words: Dengue fever, Hyperbilirubinemia, AST, ALT.
Anais do 1º Simpósio Internacional de Fononcologia do Licep-INCA
Authors: Instituto Nacional de Câncer José Alencar Gomes da Silva Serviço de Cabeça e Pescoço do 
Published: August 2019

O evento promoveu o encontro entre profissionais especializados na área, possibilitando a atualização profissional, divulgação e incentivo a pesquisas na área da Fononcologia. Os expectadores assistiram a palestras com grandes nomes da Fononcologia e com a referência da equipe multidisciplinar do INCA discutindo sobre os mais diversos temas que abrangem a área.
Nessa oportunidade, também tivemos a reunião das ligas de Fononcologia brasileiras como estratégia de proporcionar aos acadêmicos de Fonoaudiologia um maior aprofundamento em assuntos referentes à oncologia, além de ser um ambiente de obtenção de conhecimento e troca de experiências com profissionais referenciados na área e de inserção do acadêmico nas atividades relacionadas a essa especialidade.
Kajian Potensi Daur Ulang Sampah Makanan Restoran di Kota Padang
Authors: Dewilda Yommi , Aziz Rizki , Fauzi Mhd. 
Published: August 2019

<p>The purpose of this research is to study the recycling potency of food waste from restaurants in Padang City by measuring the food waste generation and its composition. Sampling and analysis were carried out based on SNI 19-3964-1994. It was performed for eight consecutive days at fifteen different sampling locations which include restaurants, cafes, fast food, and food courts. The result of this research showed that the average generation unit of restaurant food waste in the city of Padang was 0.105 kg/cap/day in weight units or 0.955 liters/cap/day in unit volume. The total generation of restaurant food waste was 132 liters/day which consists of organic waste (food scraps, leaves, fruit skin, vegetables, eggshells, bones), plastic (plastic bottles, packaging, bags, straws, and spoons), paper (tissue, packaging paper, paper containers, cartons), and others (styrofoam, broken glass, smoked cigarette remains, cans, glass bottles). Organic waste has the largest percentage by the composition of 70.69%, and that of plastic was at 11.35%. The study further showed that the recycling potency of restaurant food waste in Padang City was made up of 7.65% paper, 51.32% plastic, 59.86% glass, 100% nonferrous metal and 91.71% organic waste. Conclusively, recycling and composting method were recommended to process the restaurant food waste.</p>
Optimasi Suhu Aktivasi Proses Pembuatan Arang Aktif Limbah Tulang Kambing
Authors: Wardani Sari , Mirdayanti Rina 
Published: August 2019

<p>Livestock waste, such as bone, has always been ineffectively exploited. Bones contain organic compounds that can be further processed into usable products such as charcoal and activated charcoal. This research, therefore, aims to identify the optimum temperature conditions suitable for the manufacturing process of activated charcoal from goat bone waste using thermal activation. The study uses a two-stage process which is carbonization and thermal activation. Activation temperatures used in the process were at a temperature of 500 °C, 600 °C and 700 °C for three hours. The results of the characteristics of activated charcoal thermally produced in this research met the Indonesian National Standard 06-3730-1995 about technical activated charcoal, and the optimum conditions were at an activation temperature of 500 °C. These characteristics include the values of the water content at 1.210%, ash content at 2.034%, absorption of iodine 926 mg/g, volatile matter of 0.434% and fixed carbon of 96.616%.</p><p> </p>
Analisis Kondisi Eksisting Jaringan Pipa Distribusi Air Bersih Kelurahan Simpang Rumbio, PDAM Kota Solok
Authors: Ridwan Ridwan 
Published: August 2019

<p>This research is intended to determine the hydraulic conditions of the clean water distribution network in Simpang Rumbio Village by Solok City PDAM, in order to resolve water problems that often do not flow in the city border area and its surroundings. PDAM Solok City must be able to meet customers’ clean water needs from aspects of quality, quantity and continuity. From the data of active customers of PDAM Kota Solok in 2018, the average level of clean water usage is 806 liters / customer / month or 130 liters / person / day, with an average water loss rate of 43.17%. The nodes included in Epanet 2.0 Software are 7 nodes, with the initial node P being a reservoir equipped with a capacity distribution pump of 30 liters / second and a head of 60 meters around the CEC IPA area. The six other nodes are the point of collection for active customers in Simpang Rumbio Subdistrict as many as 1,547 customers with a total distribution pipe length of 6,300 meters Epanet 2.0 analysis results, there is a negative pressure on node 5 (Prosecutor’s Office) (-0.18) meters and node 6 (Saok Laweh) (-4, 5) meters. The alternative solution is by replacing pipe 4 from a diameter of 100 mm to 150 mm type PVC, or increasing the specifications of the pump head to 70–80 meters</p>
Analisis Kualitas Air Laut Sebagai Bahan Baku Garam di Provinsi Aceh
Authors: Bahagia Bahagia , Afrizal Afrizal 
Published: August 2019

<p>Currently barriers are still faced by salt farmers because they still use traditional technology in salt production so traditional farmers are less competitive than other modern salt products. The method of data collection was carried out by analyzing sea water quality survey and test at the Research and Development Agency of the Industrial Research and Standardization Center of Industrial in Banda Aceh. This study aims to obtain the results of measuring the quality of sea water that will be used as old water as raw material for salt. The results showed that the highest degree of Bauma came from the sample of Alue Rambut Lembah Sabil and Sejahtera Manggeng in the amount of 4 Be. Furthermore, the highest NaCl level originated in the Sejahtera Mangeng sample by 3%, the highest iodine (KiO3) from the Sejahtera Manggeng sample of 0.421 mg / kg. The biggest lead (Pb) test results came from the Sejahtera Mangeng sample of 0.2224 mg / L. Furthermore, the test results of Cadmium (Cd), Water Mercury (Hg) and Arsenic (As) with the AAS method are at the detection limit of the test equipment at &lt;0,0004 mg / L, &lt;0,0005 mg / L and &lt;0 0002 mg / L</p>
СПЕКТР ГЕНОТИПОВОЇ МІНЛИВОСТІ У РОСЛИН СОРТІВ ТОМАТА ПІСЛЯ БАГАТОРАЗОВОГО ГАММА-ОПРОМІНЮВАННЯ НАСІННЯ
Authors: Samovol O. P. , Mogilnay O. M. , Kondratenko S. I. 
Published: August 2019

Мета. Виявити норму реакції мутабільності генома рослин різного напряму сортів томата на багаторазове γ-опромінювання їх насіння. Методи. Індукованого фізичного мутагенезу, біохімічної оцінки плодів томата, розрахунково-аналітичної оцінки, статистичної обробки одержаних результатів. Результати. Виявлений рівень норми реакції мутабільності якісних і кількісних ознак у рослин різних сортів томата на багаторазове γ-опромінювання їх насіння, а саме: 1) одержання рослин з одномаркерними і багатомаркерними генами за чітким їх фенотиповим проявом; 2) одержання рослин з високими показниками цінних господарських ознак (формування високого репродуктивного навантаження плодів, добір мутантних рослин за високою ранньостиглістю та низькою тривалістю вегетаційного періоду, високою продуктивністю в поєднанні з високими показниками біохімічних компонентів у плодах). Висновки. Багаторічні дослідження з фізичного мутагенезу томата дозволили встановити диференційовану норму реакції похідних мутантних форм від сортів (за часткою рослин із зав’язаними плодами, ранньостиглих рослин, а також довжини вегетаційного періоду), яка залежить від генетичної основи сорту, варіанта обробки, дозиγ-опромінювання та порядку розташування китиць на рослинах. Відібрані мутантні форми були з явним перевищенням рівня прояву цінних господарських ознак порівняно з вихідними сортами. Крім того, одержано форми з одномаркерними генами – стерильність пилку (ген ms), зміна вегетативних органів – картопляний тип листка (ген с) та індетермінантний тип куща (ген sp +), крапчасте забарвлення поверхні листка (ген m-2), жовте забарвлення плоду (ген r), “золоті” смужки на епідермісі зрілого плоду (ген gs), брудно- червоне забарвлення плоду (ген gf), жовте забарвлення сім ’ядоль (ген wv) та ін., а також з багатома-ркерними генами: r, j2, u, sp+, c, aw, gs у сорту Елеонора.
ВИРОЩУВАННЯ БУРЯКА СТОЛОВОГО ЗА РІЗНИХ ТЕХНОЛОГІЙ В УМОВАХ ПРАВОБЕРЕЖНОГО ЛІСОСТЕПУ УКРАЇНИ
Authors: Vdovenko S. A. 
Published: August 2019

Метою досліджень було порівняння ефективності комплексного використання біопрепаратів та їх дозування за вирощування столового буряка в умовах відкритого ґрунту до існуючої інтенсивної тех-нології вирощування. Методи. До схеми досліду входили варіанти, де застосовували рекомендовану та подвійну дозу біопрепаратів компанії БТУ-центр (Україна). За контроль взято технологію вирощування столового буряка за інтенсивної технології, яка є рекомендованою для даного району Насіння двох сортів столового буряка Червона куля та Носівський плоский висівали в І декаді травня за рядкової схеми висіву 45 см. Під час ведення досліду використовували загальноприйняті методи, а саме: польовий і лабораторно-польовий. Їх використовували для спостереження за процесами росту, розвитку і формування продукції; метод синтезу для формування висновків, статистичний аналіз – встановлення ефективності технології вирощування. Результати. Використання органічної технології вирощування столового буряка і застосування рекомендованої дози біопрепаратів подовжує вегетаційний період на 2–3 доби по сортах Червона куля та Носівський плоский. Застосування такої технології у відкритому ґрунті впливає позитивно на біометричні показники рослини, де кількість листків збільшується від рекомендованої дози препаратів до 25 шт./рослині, а за подвійної дози – до 26 шт./рослині. Одночасно, рекомендована доза біопрепаратів збільшує довжину листка до 17 см, під час вирощування сорту Червона куля ширина листка збільшується на 12–25 %, а за вирощування сорту Носівський плоский на 11 %. Також, рекомендована або подвійна доза біопрепаратів компанії БТУ- центр збільшує масу коренеплоду до 212,9–220,8 г та позитивно впливає на довжину коренеплоду сорту Червона куля. Органічне вирощування столового буряка, на основі рекомендованої дози біопрепаратів, збільшує діаметр коренеплоду до 8,1–8,4 см по сортах Носівський плоский та Червона куля. Висновки. З метою отримання високих і сталих врожаїв коренеплодів столового буряка під час вирощування сортів Червона куля і Носівський плос-кий слід застосовувати органічну технологію вирощування із використанням біопрепаратів компанії БТУ-центр. Бактерії, які входять до складу препаратів своєчасно забезпечують рослину елементами живлення, впливають на процеси росту та формування стандартного коренеплоду, зменшують кількість патогенної мікрофлори та шкідників . Рекомендована доза і кількість бактерій або подвійне їх збільшення сприяють у формуванні технічної стиглості продуктового органу, накопиченні поживних елементів і формуванні високої врожайності. Вирощування столового буряка за органічної технології та використанні рекомендованих доз біопрепаратів сприяє в підвищенні врожайності до 40,1 т/га по сорту Носівський плоский та до 42,2 т/га по сорту Червона куля, а застосування подвійної дози біопрепаратів сприяє в підвищенні врожайності до 38,0–39,4 т/га, що збільшує врожайність коренеплодів столового буряка лише на 10–13 %.