bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changing Incidence of Uterine Cancer in Rural Egypt: Possible Impact of Nutritional and Epidemiologic Transitions
Authors: Alshahrani Saad , Hablas Ahmed , Chamberlain Robert M. , Meza Jane , Remmenga Steven , Seifeldin Ibrahim A. , Ramadan Mohamed , Soliman Amr S. 
Published: July 2019

PURPOSEUterine cancer is a top-ranking women’s cancer worldwide, with wide incidence variations across countries and by rural and urban areas. Hormonal exposures and access to health care vary between rural and urban areas, globally. Egypt has an overall low incidence of uterine cancer but variable rural and urban lifestyles. Are there changes in the incidence of uterine cancer in rural and urban areas in middle-income countries such as Egypt? No previous studies have addressed this question from a well-characterized and validated population-based cancer registry resource in middle-income countries. The aim of this study was to explore the differences in clinical and demographic characteristics of uterine cancer over the period of 1999 to 2010 in rural and urban Gharbiah province, Egypt.METHODSData were abstracted for all 660 patients with uterine cancer included in the Gharbiah Population-based Cancer Registry. Clinical variables included tumor location, histopathologic diagnosis, stage, grade, and treatment. Demographic variables included age, rural or urban residence, parity, and occupation. Crude and age-adjusted incidence rates (IRs) and rate ratios by rural or urban residence were calculated.RESULTSNo significant differences were observed in most clinical and demographic characteristics between rural and urban patients. The age standardized IR (ASR) was 2.5 times higher in urban than in rural areas (6.9 and 2.8 per 100,000 in urban and rural areas, respectively). The rate ratio showed that the IR in urban areas was 2.46 times the rate in rural areas.CONCLUSIONThis study showed that the disease IR in rural areas has increased in the past decade but is still low compared with the incidence in urban areas in Egypt, which did not show a significant increase in incidence. Nutritional transitions, obesity, and epidemiologic and lifestyle changes toward Westernization may have led to IRs increasing more in rural than in urban areas in Egypt. This pattern of increasing incidence in Egypt, which used to have a low incidence of uterine cancer, may appear in other middle-income countries that experience emerging nutritional and epidemiologic transitions. The rate of uterine cancer in urban areas in Gharbiah is almost similar to the corresponding rates globally. However, the rate in rural areas in this population has increased over the past decade but is still lower than the corresponding global rates. Future studies should examine the etiologic factors related to increasing rates in rural areas and quantify the improvement in rural case finding.
The New Neoliberal Turn in Argentina
Authors: Catanzaro Gisela , Stegmayer María , Rolón Machado Pedro J. 
Published: July 2019

AbstractThis article examines reconfigurations of neoliberalism as these can be traced in emergent forms of ideological interpellation in Argentina. Privileging an analysis of dominant modes of public discourse, we posit an inextricable relationship between—and simultaneous deployment of—the “punitive” elements of this interpellation and its new, entrepreneurial dimension. This last component, opposed to the first only nominally, exalts individual potency and delivers an “amicable” appeal to a wholesome and reconciled common life. Taking into account the Janus-faced, omnipotent, moralizing, and sacrificial character of this new community of “entrepreneurs cum punishers,” we focus on the idiosyncratic forms that this relationship takes in our current historical conjuncture, distinguishing it from previous inflections and ideological configurations of neoliberalism in contemporary Argentina. Finally, we seek to understand the ethical and political implications of this specific interpellative mode for the process of subject formation.
Preoperative surgical risk stratification in osteosarcoma based on the proximity to the major vessels
Authors: Fujiwara T. , Medellin M. R. , Sambri A. , Tsuda Y. , Balko J. , Sumathi V. , Gregory J. , Jeys L. , Abudu A. 
Published: July 2019

Aims The aim of this study was to determine the risk of local recurrence and survival in patients with osteosarcoma based on the proximity of the tumour to the major vessels. Patients and Methods A total of 226 patients with high-grade non-metastatic osteosarcoma in the limbs were investigated. Median age at diagnosis was 15 years (4 to 67) with the ratio of male to female patients being 1.5:1. The most common site of the tumour was the femur (n = 103) followed by tibia (n = 66). The vascular proximity was categorized based on the preoperative MRI after neoadjuvant chemotherapy into four types: type 1 > 5 mm; type 2 ≤ 5 mm, > 0 mm; type 3 attached; type 4 surrounded. Results Limb salvage rate based on the proximity type was 92%, 88%, 51%, and 0% for types 1 to 4, respectively, and the overall survival at five years was 82%, 77%, 57%, and 67%, respectively (p < 0.001). Local recurrence rate in patients with limb-salvage surgery was 7%, 8%, and 22% for the types 1 to 3, respectively (p = 0.041), and local recurrence at the perivascular area was observed in 1% and 4% for type 2 and 3, respectively. The mean microscopic margin to the major vessels was 6.9 mm, 3.0 mm, and 1.4 mm for types 1 to 3, respectively. In type 3, local recurrence-free survival with limb salvage was significantly poorer compared with amputation (p = 0.025), while the latter offered no overall survival benefit. In this group of patients, factors such as good response to chemotherapy or limited vascular attachment to less than half circumference or longitudinal 10 mm reduced the risk of local recurrence. Conclusion The proximity of osteosarcoma to major blood vessels is a poor prognostic factor for local control and survival. Amputation offers better local control for tumours attached to the blood vessels but does not improve survival. Limb salvage surgery offers similar local control if the tumour attachment to blood vessels is limited. Cite this article: Bone Joint J 2019;101-B:1024–1031.
The effect of femoral shortening in the treatment of developmental dysplasia of the hip after walking age
Authors: Castañeda P. , Moscona L. , Masrouha K. 
Published: July 2019

Purpose The optimal treatment for late-presenting developmental dysplasia of the hip (DDH) is controversial. High tension forces after hip reduction increase the pressure on the femoral head, potentially causing avascular necrosis. Femoral shortening (FS) is commonly used as a means to decrease the pressure on the femoral head. We examined the effect of FS on the outcomes of patients with late-presenting DDH. Methods A total of 645 hips of a late-presenting DDH cohort treated with open reduction and iliac osteotomies were retrospectively reviewed; 328 hips had a FS performed (FS+) and 317 (FS-) had not. The mean age was 3.9 years (sd 1.55). We classified the hips with the Tönnis and International Hip Dysplasia Institute (IHDI) methods; and the Pediatric Outcomes Data Collection Instrument (PODCI), Iowa Hip Score (IHS) and Severin classification as outcome measurements. Results The FS- group had higher scores in PODCI (median 95 points; interquartile range (IQR) 78 to 91) and IHS (median 91 points; IQR 64 to 88) than the FS+ group (PODCI: median 94 points; IQR 69 to 89 points; IHS: median 89 points; IQR 62 to 87). The mean Severin scores were similar (FS- 2.65; FS+ 2.5; p = 0.93) but the FS– group had higher rates of good and excellent outcomes (FS- 56%; FS+ 41%; p < 0.00001) and lesser dislocation rates (FS- 6%; FS+ 14%; p = 0.16). Conclusion Although FS should be used when a hip cannot be reduced without undue tension, our results indicate that this procedure is not necessarily related to a better outcome. Level of evidence Therapeutic, Level III.
The impact of nonosteogenic factors on the expression of osteoprotegerin and RANKL during human fracture healing
Authors: Starlinger Julia , Kaiser Georg , Thomas Anita , Sarahrudi Kambiz 
Published: July 2019

Objectives The osteoprotegerin (OPG) and receptor activator of nuclear factor kappa-B ligand (RANKL) balance is of the utmost importance in fracture healing. The aim of this study was therefore to investigate the impact of nonosteogenic factors on OPG and RANKL levels. Methods Serum obtained from 51 patients with long bone fractures was collected over 48 weeks. The OPG and serum sRANKL (soluble RANKL) concentrations were measured using enzyme-linked immunosorbent assay (ELISA). Smoking habit, diabetes, and alcohol consumption were recorded. Results Age and sex greatly influenced preoperative serum levels of OPG and sRANKL but differences were even more pronounced during fracture healing. Statistical significance was observed for overall serum levels of OPG (p = 0.001) and sRANKL (p < 0.001) in older men and women (age greater than 50 years). Interestingly, OPG levels increased over time in older women but decreased over time in older men. Conclusion These data suggest that nonosteogenic factors, most significantly age and sex, have a major impact on sRANKL and OPG levels. Given the established association of OPG and sRANKL levels and nonunion, these findings seem to be of clinical relevance. Cite this article: J. Starlinger, G. Kaiser, A. Thomas, K. Sarahrudi. The impact of nonosteogenic factors on the expression of osteoprotegerin and RANKL during human fracture healing. Bone Joint Res 2019;8:349–356. DOI: 10.1302/2046-3758.87.BJR-2018-0116.R3.
Investigation of the relationship of the morphometric measurements of the hands and fingers with the personality traits of leadership
Authors: Sertel Meyvaci Seda , Kosif Rengin , Diramali Murat , Baki Tugce 
Published: July 2019

Background: The hand is a functionally critical organ at the distal end of the upper extremity. Also, the creases in the hands and the digital flexion creases on the fingers are the important external anatomical landmarks.Objectives: There are no studies found in the literature, linking solely the leadership personality traits with the anthropometric measurements of the hand.Methods: This descriptive study was to investigate the relationship between the 44 anthropometric measurements about hand, and the leadership personality traits in young adults from both genders.Results: When the leadership frames were compared by the scores, human resource leadership scores were significantly higher in the females. The charismatic leadership frame scores positively correlated with the parameters in males; including the breadth of the right hand, the breadth of the left hand, the index finger length of the left hand, and the distal phalanx length of the index finger on the left hand. The transformational leadership score was positively correlated with the left hand width and with the distal phalanx of the index finger on the left hand. In females, it was found out that the frames of human leadership and charismatic leadership correlated negatively with the length of the right thumb.Conclusions: According to the results of our study, we concluded that the breadth of the hand and the measurements of the thumb and the index fingers can provide opinion on leadership personality traits.Â Â
The Impact of Social Transfers on Poverty Reduction in EU Countries
Authors: Miežienė Rasa , Krutulienė Sandra 
Published: July 2019

AbstractAvailable studies indicate a strong negative correlation between poverty and social expenditures in EU countries. It means that the country’s at-risk-of-poverty rate tends to erode with increasing social expenditure. However, the studies have demonstrated that the impact of government spending on poverty may vary according to the sector of spending, how well it is targeted, and the way in which it is financed. Some countries manage to achieve a rather significant poverty rate reduction even with relatively low, in the context of other Member States, social expenditure (percentage of GDP). This suggests that in order to reduce poverty rates, it is important to consider not only the amount allocated to social spending, but also the areas the social transfers are channelled to. The article aims to analyse how the composition and the extent of social spending/transfers may affect poverty reduction in EU countries. The analysis showed that social protection transfers reduce the percentage of people at-risk-of-poverty in all countries, however, to a very different extent. Regression analysis demonstrated that social exclusion and family/children expenditure was found to be the most important predictor for a relative antipoverty effect of social transfers: even a small percentage increase in such expenditure allows quite a significant increase in the relative antipoverty effect of social transfers.
On a class of norms generated by nonnegative integrable distributions
Authors: Falk Michael , Stupfler Gilles 
Published: July 2019

Abstract
We show that any distribution function on ℝ
d
with nonnegative, nonzero and integrable marginal distributions can be characterized by a norm on ℝ
d+1, called F-norm. We characterize the set of F-norms and prove that pointwise convergence of a sequence of F-norms to an F-norm is equivalent to convergence of the pertaining distribution functions in the Wasserstein metric. On the statistical side, an F-norm can easily be estimated by an empirical F-norm, whose consistency and weak convergence we establish.
The concept of F-norms can be extended to arbitrary random vectors under suitable integrability conditions fulfilled by, for instance, normal distributions. The set of F-norms is endowed with a semigroup operation which, in this context, corresponds to ordinary convolution of the underlying distributions. Limiting results such as the central limit theorem can then be formulated in terms of pointwise convergence of products of F-norms.
We conclude by showing how, using the geometry of F-norms, we may characterize nonnegative integrable distributions in ℝ
d
by simple compact sets in ℝ
d+1. We then relate convergence of those distributions in the Wasserstein metric to convergence of these characteristic sets with respect to Hausdorff distances.
The Physical Parameters of EDFA and SOA Optical Amplifiers and Bit Sequence Variations Based Optical Pulse Generators Impact on the Performance of Soliton Transmission Systems
Authors: Amiri I. S. , Rashed Ahmed Nabih Zaki , Ramya K. C. , Vinoth Kumar K. , Maheswar R. 
Published: July 2019

Abstract
This study has outlined the effects of physical parameters of erbium doped fiber amplifier (EDFA), semiconductor optical amplifier (SOA) on the performance of amplified soliton transmission systems. Injection current-based SOA, EDFA length is taken into account. It is observed that the optimum soliton power and signal per noise ratio are achieved with 5 m EDFA length and 900 mA injection current-based SOA. As well as the bit sequence variations based user defined bit sequence generator are employed in order to measure the soliton transmission system performance. The signal per noise ratio is enhanced with 4 bit sequence. Soliton peak power, output soliton power, and maximum Q-factor are optimized with 8 bit sequence for soliton propagation length of 150 km and possible transmission data rates of 160 Gb/s. Improvement percentage ratio in soliton peak power by using two amplification techniques a long propagation length is deeply stimulated with optiwave simulation program.
Macronutrient analysis of preterm human milk using mid-infrared spectrophotometry
Authors: Bulut Özgül , Çoban Asuman , İnce Zeynep 
Published: July 2019

Abstract

Background
Human milk is the optimal source of nutrition for preterm infants. However, breast milk alone is often not sufficient to satisfy the high nutritional needs for growth and development in preterm infants. Fortified human breast milk is the best way to meet the nutritional needs of preterm infants. Human breast milk is fortified according to the estimated nutrient content of mature breast milk; however, because the content of breast milk is highly variable, the macronutrient support may be more or less than needed. The goal of this study was to analyze the macronutrient content of preterm human milk during the first 6 weeks of lactation.

Methods
The study included 32 mothers of preterm infants with a gestational age of ≤32 weeks. Breast milk was collected in 24-h cycles and analyzed daily using mid-infrared (MIR) spectroscopy. We measured protein, fat and lactose concentrations in the breast milk, and the energy content was calculated.

Results
The protein content was high during the first weeks of lactation, but decreased as lactation progressed. The fat, energy and lactose contents of the breast milk were low during the first 2 weeks of lactation, increased as lactation progressed and remained constant thereafter. In women with high body mass index (BMI), higher protein levels were found in transitional milk. In women who had high income level, higher fat and energy levels were found in transitional milk.

Conclusion
Our findings indicate that the macronutrient content of preterm breast milk changes throughout the course of lactation, with BMI and income level. Knowledge of the macronutrient composition of breast milk is necessary to ensure that preterm infants receive the appropriate types and quantities of nutrients to promote optimal growth, and to ensure that breast milk is fortified according to individual needs. Our findings may be useful for the provision of optimal nutritional support for preterm infants.
Bachrach, David S., The Benefices of Counts and the Fate of the Comital Office in Carolingian East Francia and Ottonian Germany
Authors: Bachrach David S. 
Published: July 2019

Abstract
The long-standing historiographical controversy about the nature of the comital office in East Francia and Ottonian Germany has turned on the same set of questions for more than a century: over whom did the count exercise jurisdiction, what was the basis of count's jurisdiction, and what was the source of the material assets that allowed counts to perform their duties? Left out of these discussions, however, has been the related problem of the control exercised by the king over the assets attached to the comital office, denoted variously as the res de comitatu, the count's ministerium, or simply the comitatus. The following study examines this question from the reign of Emperor Louis the Pious (814–840) through the death of Emperor Henry II (1002–1024), and concludes that the Carolingian and Ottonian rulers maintained tight control over the fiscal assets assigned to counts, and were able to recover them and reassign them as the royal government saw fit. This conclusion is at odds with much of the scholarship on the comital office in East Francia and Ottonian Germany that presents counts holding erstwhile fiscal assets in allodial tenure and the de facto transformation of the comital office into a hereditary possession.
European Research Infrastructure Consortia: International Organization under European Law or Legal Entities Sui Generis?
Authors: Chetverikov A. O. 
Published: July 2019

The paper in the theoretical and practical aspects considers the legal status and the legal nature of a new, unique organizational legal form of legal entities created by the law of the European Union in the development of integration processes in the infrastructure of research activities, including megascience. The adoption of the EU legislation on European research infrastructure consortia is due to the desire to overcome the shortcomings of the «classical» forms of implementation of international scientific and infrastructure projects, namely the forms of international intergovernmental organizations and national legal entities with international membership.The EU regulation on European research infrastructure consortia, adopted in 2009, provides that as their main task such consortia have the construction and operation of the research infrastructure for the purpose of forming the European research area.In terms of the structure, establishment and operation, European research infrastructure consortia have common features with international intergovernmental organizations, limited liability companies, as well as a number of unique features arising from the application of the EU integration law to them. Hence, the complex question on the legal nature of European research infrastructure consortia arise. The author shows the impossibility of reducing consortia to international intergovernmental organizations. Similarly, consortia are not equivalent to national legal entities. While agreeing with the European Commission, the author concludes that consortia should be considered as legal entities sui generis (of a special kind), although this solution is not ideal. As a practical result of the study, the author proposes to start the preparation of the Agreement on the Eurasian Scientific and Technological Integration immediately within the framework of the Eurasian Economic Union and to provide for provisions on the Eurasian consortia of research infrastructure, which will be an analogue and competitor for the European consortia considered in the paper.
Adaptation disorders caused by nephrectomy
Authors: Shormanov Igor S. , Los Marina S. , Kosenko Maxim V. 
Published: July 2019

Currently, nephrectomy is performed for various diseases, and the number of this type of surgery does not have a clear tendency to decrease. Operational stress is accompanied by a triggering mechanism for a wide range of disorders, among which psycho-emotional and vegetative (vascular) reactions are important clinical markers. The study of the systemic adaptive reactivity of the body after nephrectomy will provide an integrated approach to the study of the problem of the postoperative period and the rehabilitation of the patient in clinical practice.
Objective: to identify the effect of nephrectomy on the overall adaptive response of animals when white rats are exposed to damaging physical loads (acute hyperthermia) and chemical (acute alcohol poisoning, nephrotoxic agents) of nature, normobaric hypoxia, limiting muscular loads and immobilization stress.
The results of the experiment showed that laboratory animals with a single kidney become more sensitive (1.5 times) to nephrotoxic agents. Analysis of the effect of nephrectomy on the overall adaptive response of animals under the influence of various damaging factors to reduce the body’s resistance to hypoxia by 20% (p > 0.05); to limit muscular loads – by 25% (p > 0.05); hyperthermia – by 25% (p < 0.05); chemical agents – by one third (p < 0.05); to immobilization stress – by 28% (p < 0.05).
Conclusion. The study demonstrated a significant negative impact of nephrectomy on the overall adaptive capacity of the body and allowed to clarify the functional characteristics of the general adaptation disorders in connection with this operation.