bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lessons learned from setting up a hospital-based national registry for venous thromboembolic disorders in India
Authors: Aggarwal Sumit , Rulu Peteneinuo , Tabassum Heena 
Published: November 2024

ABSTRACT

Introduction:
Health registries are instrumental in tracking trends in the number of people with diseases, monitoring treatment options, and assessing health outcomes. This research examines the challenges of establishing and maintaining a venous thromboembolism (VTE) registry in the Indian context.

Methods:
A mixed-method approach with purposive sampling was conducted to capture the challenges faced by individuals playing key roles in the establishment and operation of the national registry on VTE. This study focused on 10 questions related to technological infrastructure, resource optimization, data collection and management, coordination and collaboration, regulatory compliance, and political influences and were documented using a semi-structured questionnaire and telephonic interviews.

Results:
Technological, recruitment, and follow-up challenges were prominently highlighted with issues related to data entry, system glitches, changes to the data entry forms, and potential participant reluctance.

Conclusion:
Findings from this study highlight the multifaceted challenges experienced during the establishment of a national registry on VTE. By integrating insights from our findings into suggestions, this discussion reflects the specific challenges faced by the research project and offers evidence-based strategies for mitigating these challenges.
Analysis of risk factors in angiographically proven coronary artery disease in rural and urban Indian population. Prospective observational multicentre study: Kashmir Heart Survey
Authors: Sheikh Jan Mohd , Dar Mohd Iqbal , Rather Hilal Ahmed , Hafeez Imran , Lone Aijaz Ahmed , Rashid Aamir , Bilal Syed 
Published: November 2024

ABSTRACT

Background:
The global burden of cardiovascular diseases is increasing rapidly, and changing trends in epidemiological risk factors are identified among diverse Indian population. There has been a significant increase in heart attack deaths over the past 3 years after the COVID-19 pandemic. Are we missing a link? There is an urgent need for studies to confirm any epidemiological shift in coronary artery disease (CAD) risk factors.

Aims and Objectives:
To analyse the risk factors in patients with established CAD in rural and urban Indian Kashmiri populations in the post-COVID period.

Material and Methods:
A prospective observational study of all patients with angiographically proven CAD who have undergone revascularisation or have a clinical suspicion of CAD on the basis of symptoms or positive stress test and later proven to have CAD on coronary angiograms, coming from rural and urban areas of Jammu and Kashmir were enrolled for the study and screened for various modifiable and non-modifiable CAD risk factors. Data was compiled and analysed to know the pattern of various CAD risk factors in our population.

Results:
The study included total 600 patients (rural and urban 300 each), mean age was 59.13 ± 11.62 years. Male patients were 65.50% with a mean age of 57.53 ± 14.17 years and female patients were 34.50% with a mean age of 62.16 ± 10.02 years. In rural subgroup of 300 patients mean age was 60.99 ± 16.86 years and in the urban population we found a mean age of 57.26 ± 16.21 years. The most common risk factor was smoking in 76% rural and 67% urban. Diabetes (39% rural, 43% urban), dyslipidaemia (47.33%, 48.66% urban), hypertension (61% rural, 66% urban), obesity (23% rural, 29.33% urban) and physical inactivity (33.66% rural, 37.33% urban.

Conclusion:
CAD manifests earlier in males and urban populations. Smoking is the most common risk factor for CAD in the Kashmiri Indian population and is more common in the rural population. Coronary artery disease risk factors, such as physical inactivity, diabetes, smoking, hypertension, obesity and dyslipidaemia, are more common in the urban population. Preventive strategies should focus on modifying the risk factors to decrease the prevalence of CAD in communities.
Domestic violence against women in rural areas of Saharanpur: A population-based study on prevalence and risk factors
Authors: Rao Chappavarapu H. , Jain Bhavna , Sachan Divyata , Devjibhai Chaudhari M. 
Published: November 2024

ABSTRACT

Background:
Domestic violence (DV) against women is a global problem and is present in every country. It is a matter of serious concern in most communities and cultures and has consequences on women’s mental, physical, reproductive, and sexual health. The study aimed to determine the prevalence and pattern of DV among married women.

Materials and Methods:
A community-based, cross-sectional study was conducted among 400 reproductive age group females in the rural area of district Saharanpur for a period of six months using multistage random sampling.

Results:
The prevalence of DV was found to be 21%. The most common type of DV was physical violence (18%) followed by psychological violence (12.8%), financial violence (5.5%), and sexual violence (2.3%). The major perpetrators of DV were the husbands in 79% of the cases. Regression analysis depicted a significant association between age, education of husband, husband’s addiction, and depression of study participants with events of DV. Multivariate analysis shows only the addictions of husbands and the depression status of study participants to be significantly associated with DV.

Conclusion:
The prevalence of DV was 21% which is still high and appropriate measures should be taken to strengthen the laws for women and to empower them.
Prevalence and association of self-medication practices with personal and educational factors among university employees of Saudi Arabia: A cross-sectional study
Authors: Habib Syed Shahid , Al-khlaiwi Thamir , Almushawah Abdullah , Alsomali Abdulaziz , Bin Ateeq Abdulrahman Abdulaziz A. , Aljarrah Faisal Abdulkader , Aldeligan Saleh Husam , Alfwzan Faisal Soud , Habib Syed Abubakar , Habib Syed Mohammad 
Published: November 2024

ABSTRACT

Background and Objective:
Self-medication (SM) is an emerging practice in both developing and developed countries. The commonality of this behavior is observed in patients with specific environments. The current study endeavored to determine the prevalence of SM practices and their correlated factors among academic employees in Saudi Arabia.

Methods:
A cross-sectional study was conducted at King Saud University Hospital, recruiting 383 participants. The participants received an online survey on self-medication practices. The data were analyzed using descriptive statistics and regression analysis.

Results:
In the study, all the participants reported practicing SM at least one time. Of those who practiced SM, 66.7% (102) were unmarried with a significant difference (P = 0.036) while 68.0% (117) had no children (P = 0.003). Non-Government employees and unemployed participants had the highest percentage of experiencing SM (70.5%, n = 31, P = 0.036). Our results reveal that health perceiving, life satisfaction, and religious reasons were not significantly associated with practicing SM with P value = 0.704, 0.535, and 0.482, respectively. In the univariate model, gender, marital status, and the number of children revealed a significant correlation with SM (P value = 0.136, 0.058, and 0.040), respectively. SM was 1.4 times as likely if the participant was female and 1.3 if the participant was unmarried. The multivariate regression model shows that gender and marital status lost their significance while number of children (P = 0.023) was significantly correlated with SM. Our results also show the main reasons for self-medication were prior knowledge (25%), time-consuming consultations (21.6%), the belief that the condition did not require a doctor (22.4%), and previous experience with similar symptoms (23%) while major causative clinical conditions involved in SM is pain (37.5%) and fever (28.4%). It also shows that 33% experienced no side effects and 34% experienced shortness of breath as a side effect of practicing SM.

Conclusion:
Our study spotted a significant frequency of SM behavior with high prevalence among University employees. Our study shows that gender, marital status, and number of children have a significant correlation with SM. The pharmacist’s role is pivotal in promoting awareness for the safe utilization of over-the-counter drugs, and their proactive engagement is paramount. Educational health programs should be implemented to minimize SM malpractice.
Evaluation of ADHD knowledge and awareness among healthcare college interns in Riyadh, Saudi Arabia
Authors: Alnmshan Nmshan , Jameel Osama , Alsahli Abdullah , Alokail Ibrahim , Alotaibi Mamdouh , Mansy Wael 
Published: November 2024

ABSTRACT

Background:
Attention deficit hyperactivity disorder (ADHD), a neuropsychiatric disorder, is common in children and can persist into adulthood. With or without hyperactivity, it involves chronic impulsivity and inattention. Despite being a widespread illness, there is little research on ADHD knowledge and awareness among health college interns in Riyadh, KSA. Therefore, this study examined health college interns’ knowledge and awareness in Riyadh, Saudi Arabia’s capital.

Methods:
A cross-sectional study using a self-administered validated survey was used to gather demographics as well as knowledge and awareness scores in King Saud University, King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), Imam Mohammed ibn Saud, and Princess Nourah Bint Abdulrahman, and one private Almaarefa University.

Results:
This study included 322 health college interns aged 18–24; 55% were males. The Saudi Professional Practice Licensure Exams (SPPLE) were passed by 65.5% of participants from King Saud University and KSAU-HS, Riyadh’s leading medical and pharmaceutical universities. They are evenly split throughout the four GPA categories. The interns knowledgeable and aware of ADHD (scored ≥ 13 on a 20-scale score) constituted 68% of the interns. Interns who passed Saudi Professional Practice Licensure Exams graduated from pharmacy and medicine schools, and had ≥4.5 or more GPAs were more knowledgeable than other interns.

Conclusion:
As per our research, most health college interns in Riyadh were aware of ADHD; however, medical and pharmacy interns were more knowledgeable than others. This suggests that other health colleges should revamp their ADHD and neurological illness topics curricula.
Prevalence of substance use among adolescents residing in urban slums of Vellore: A cross-sectional study
Authors: Rajamani J Bino , Reshmi YS , Pricilla Ruby A. , Prasad Jasmin H. , Baskar Mona 
Published: November 2024

ABSTRACT

Background:
Adolescent substance abuse is a growing public health concern. Adolescence is the starting point for adult substance misuse. The likelihood of acquiring dependence in adulthood is significantly decreased when substance use is not initiated during adolescence. The purpose of this study was to estimate the prevalence of substance use among teenagers, as well as to determine the age of initiation and identify the factors that are linked to substance use.

Methods:
A community-based cross-sectional study was conducted in an urban community in Vellore by a tertiary care teaching hospital. A structured questionnaire was administered by the principal investigator to all adolescent boys aged between 10 and 19 years residing in that area for the past year who gave informed consent/assent to assess the prevalence of substance use among teenagers.

Results:
The total number of adolescent boys enrolled in the study was 266. The mean (standard deviation [SD]) age of the participants was 16.14 (2.2) years, with a median age of 16 years. Out of the 266 adolescent boys, 33.8% are currently using substances and 15% were past users. The common substance used was smoking tobacco (30%), followed by alcohol consumption (29%). The minimum age of initiation of smoking tobacco and ganja use was 9 and 7 years, respectively. Significant predictors of substance usage included the participant’s educational background and the substance use of their parents.

Conclusion:
According to this community-based study’s findings, smoking tobacco was the most frequently used substance by teenagers, with a higher prevalence of current substance use. Substance misuse in the family was substantially associated with increased drug usage among teenagers. Notwithstanding having an adequate comprehension of the negative results of substance utilisation, teenagers develop this habit, which they might carry into adulthood. It is therefore necessary to establish comprehensive prevention and control programs in schools and the community that target teenagers and their parents.
Micronutrient status and associated factors of anemia among undernourished children of 5-18 years: First study from Himalayan foothills
Authors: Aswanth KS , Rajvanshi Nikhil , Kumar Vinod , Chacham Swathi , Naithani Manisha , Kumari Ranjeeta , Verma Prashant K. 
Published: November 2024

ABSTRACT

Purpose:
Undernutrition in children is a critical worldwide concern that hampers both their physical and cognitive growth. The nutritional status of school-going children and adolescents remains insufficiently addressed with no comprehensive data. This is the first study from the Himalayan foothills that aims to assess the clinical and laboratory aspects of anemia with micronutrient status in undernourished children above the age of five along with association of clinical features with anemia severity.

Materials and Methods:
A cross-sectional study was conducted involving children aged 5-18 years with undernutrition in a tertiary hospital in North India over eighteen months. We observed the prevalence of anemia, its morphological type, micronutrient status, clinical features, and demographic parameters of these children. The association of various clinical features and anthropometric parameters with the severity of anemia was determined.

Results:
Of the 200 children who were enrolled in the study, 77% were found anemic, with the proportion of mild, moderate, and severe anemia being 18.2%, 46.8%, and 35%, respectively. Iron (67%) was the most common micronutrient deficient in these children with a significant number suffering from vitamin B12 (53.9%) deficiency. Folic acid deficiency was relatively low (10.4%). Body mass index (P = 0.009), fatigability (P = 0.001), pallor (P ≤ 0.001), poor academic performance (P = 0.023), and knuckle hyperpigmentation (P = 0.018) were significantly associated with the severity of anemia.

Conclusion:
Despite the significant tread in various aspects of human development, undernutrition and anemia remain a formidable challenge, especially in developing countries. A high proportion of anemia in undernutrition indicates the gravity of the issue, yet not received the deserved attention.
Prevalence of irritable bowel syndrome in endometriosis patients: A cross-sectional study
Authors: Aldardier Nashwa , Eissa Ghaida A. , Shaheen Abdulaziz M. , Sanedi Abdullah M. , Alghamdi Talah , Habadi Rama A. , Alghamdi Sarah S. 
Published: November 2024

ABSTRACT

Background:
Despite its prevalence, limited research has explored the direct correlation between irritable bowel syndrome (IBS) and endometriosis, particularly in regions like Saudi Arabia. This study aimed to bridge this gap by investigating the prevalence of IBS among endometriosis patients and identifying associated risk factors.

Materials and Methods:
The study conducted a cross-sectional analysis, it was done at King Abdulaziz University Hospital, Jeddah. From September to December 2023. Women who were diagnosed with endometriosis and aged above 18 years old were included.

Results:
Our study revealed that 47.8% of endometriosis patients had previously been diagnosed with IBS. Interestingly, Saudi patients exhibited a significantly higher prevalence of IBS compared to non-Saudi individuals. While no substantial link emerged between IBS prevalence and other demographic or endometriosis-related factors, patients with chronic digestive conditions like food intolerance, esophageal reflux, and inflammatory colon diseases showed a higher likelihood of IBS.

Conclusions:
This study underscores a substantial association between IBS and endometriosis, urging healthcare providers to consider IBS as a potential comorbidity in affected patients. The findings stress the importance of holistic assessments and awareness regarding overlapping symptoms and risk factors. Further research is encouraged to unveil underlying mechanisms and devise optimal management strategies for individuals grappling with both conditions.
Multimodal intervention on perception and quality of life of geriatric clients regarding health promotional outcomes at a selected hospitals, Kolar, Karnataka, India
Authors: Vani R , Joseph Zeanath C. , Aranha Priya R. 
Published: November 2024

ABSTRACT

Background of Study:
Old age is a privilege for a second childhood and a new stage of opportunity and strength. Older adults are the most rapidly growing segment of the population. By 2050, 80% of all older people will live in low- and middle-income countries.

Purpose:
To evaluate the effectiveness of multimodal intervention on perception and quality of life among geriatric clients.

Methods:
Quantitative approach quasi-experimental interventional controlled study with pre-test, post-test design and follow-up for two months, adopted by using purposive sampling technique among 120 geriatric clients who gave consent for participation in the study at two different settings of hospitals from July 2022 to January 2023, Kolar. After obtaining Central Ethics Committee approval, data was obtained using the structured perception questionnaire and WHO Quality of Life questionnaire, and the Multimodal Intervention package consisting of a snake and ladder health promotion strategies game, educational video, and informational pamphlet distributed to the experimental group, whereas routine care was given to the control group followed by post-test group on the 30th and 60th day. Reinforcement was carried out by the investigator on a fortnightly basis reminders through messages. Data were analyzed by using descriptive and inferential statistics such as repeated measures of ANOVA, independent ‘t’- test, paired ‘t-test, and Chi-square.

Results:
A perception significant effect was demonstrated in the experimental group with enhanced mean, standard deviation from pre-test to post-test I and Post-test II found to be 35.1 ± 7.9, 46.3 ± 6.1, and 48.3 ± 4.7, respectively, without significant changes in the control group. Concerning quality of life, important variations were demonstrated in the experimental group with enhanced mean, SD from pre-test to post-test I and Post-test II found to be 54.76 ± 10.39, 74.15 ± 6.75 and 77.71 ± 4.99, respectively, without any significant changes in the control group.

Conclusion:
Geriatric population was the biggest beneficiary, multimodal intervention was proven to be effective and can be implemented in hospitals and community settings in improving the perception and quality of life of senior clients to foster healthy aging.

CTRI Trial Reg no: CTRI/2021/07/034632.
Neuropsychiatric complications in chronic kidney disease: Role of gender, clinical, and sociodemographic factors
Authors: Tesia Sonali S. , Nongpiur Arvind , Barman Bhupen , Lyngdoh Monaliza , Prithviraj Manoj , Roy Debjit , Das Jayanta 
Published: November 2024

ABSTRACT

Introduction:
Patients with chronic kidney disease (CKD) frequently experience neuropsychiatric conditions, such as depression, anxiety, and cognitive impairment, which not only significantly diminish their quality of life, but also contribute to longer hospitalizations, poor treatment adherence, and increased mortality. This hospital-based cross-sectional study aimed to investigate neuropsychiatric complications in CKD patients, focusing on gender differences, and clinical and other sociodemographic factors.

Materials and Methods:
Diagnosis of CKD was based on the Kidney Disease: Improving Global Outcomes (KDIGO) criteria, and patients aged 18 years or above were included. Delirium was assessed using the Confusion Assessment Method (CAM) Scale. Those without delirium underwent evaluation using the Hindi Mental Status Examination (HMSE), Brief Psychiatric Rating Scale (BPRS), and Hospital Anxiety and Depression Scale (HADS) to identify cognitive and psychiatric symptoms.

Results:
Among the 104 participants, 50% were male, with a predominant age group over 45 years (61.5%). A majority portion of the cohort was married (72.1%), employed (57.7%), and identified as Christian (56.7%). The majority of CKD cases were diagnosed as stage 5 (87.5%) and on dialysis treatment. Delirium was present in 19.2% of participants. In those without delirium, anxiety affected 46.3%, depression impacted 50.0%, and cognitive dysfunction was present in 11.1%. A gender-based analysis revealed no significant differences in age or illness duration; however, males exhibited a higher level of education (P < 0.02). While females tended to display more severe psychiatric symptoms (P < 0.06), males had more cognitive dysfunction (P < 0.08); however, these differences did not reach statistical significance. Socioeconomic status (SES) comparisons demonstrated that lower SES correlated with a reduced number of years of education (P < 0.00).

Conclusion:
Anxiety and depression were prevalent in nearly half of CKD patients, without gender or socioeconomic disparities. This underscores the imperative need for holistic, multidisciplinary interventions to effectively manage these conditions and enhance overall quality of life.
The prevalence of cyberchondria and the impact of skepticism on medical decisions among Imam Mohammed Ibn Saud Islamic University students, Riyadh, Saudi Arabia
Authors: Bin Abdulrahman Khalid A. , AL Musfir Sultan Khalid , Alforaih Abdullah Suliman , Alshehri Asim Mohammed , Aldossari Ayed Khalid , Dawood Fahad Dawood Bin 
Published: November 2024

ABSTRACT

The internet significantly impacts the occurrence and prevalence of cyberchondria because it provides easy access to a large amount of health data that can describe any medical condition in detail. Cyberchondria develops due to exposure to the vast and easily accessible online health information that causes health worries.

Objectives:
To assess the prevalence of cyberchondria among Imam Mohammad Ibn Saud Islamic University (IMSIU) students and determine the impact of patient skepticism on medical decisions.

Methods:
A cross-sectional study was conducted among IMSIU students. A questionnaire was distributed to participants via Google Forms. Data were collected and analyzed by using SPSS.

Results:
This study involved 798 respondents. Female participants represented 51.1%. Most of the participants were between 21 and 23 years old. More than one-third of students studied in the College of Medicine (36%). Almost 20% of students panicked about their condition when they read online. Excessiveness was the most severely affected construct (63.7%), followed by the reassurance subscale (46.4%). Compulsion was the least affected construct, while distress was moderately affected. Divorced and married students showed significantly higher cyberchondria severity scores than single respondents (P value = 0.020).

Conclusion:
Our findings suggested that IMSIU students had a relatively high prevalence of cyberchondria. More efforts are required to raise public awareness of appropriate internet usage for health-related information.