bluuebunny/crossref_metadata_2025_split huggingface dataset:
HYPERHOMOCYSTEINEMIA AS A FACTOR OF FIBRINOLYSIS DISTURBANCES IN PATIENTS WITH ACTIVATED INTRAVASCULAR COAGULATION
Authors: Subbotina T. F. , Zhloba A. F. 
Published: December 2018

Background. High blood concentration of D-dimer is a reliable marker of activation of intravascular coagulation, but does not provide unambiguous information about the functional potential of the ibrinolytic system.Objective. To determine the contribution of hyperhomocysteinemia (HHcy) in ibrinolysis disturbances in patients with activated intravascular coagulation. Design and methods. Plasma samples of 141 patients with activated intravascular coagulation of various etiologies [82 women (58,2 %) and 59 men (41,8 %), mean age 53,2 ± 7,8 years] with the level of D-dimer > 500 ng/ml were studied. The level of total Hcy (tHcy) was determined by high-performance liquid chromatography. In 57 samples ibrinolytic capacity was investigated by turbidimetric global coagulation and ibrinolysis test using as inducers thrombin and tissue plasminogen activator, respectively. 20 samples of donors matched for age and sex served as a comparison group. Results. In 52 patients (36,9 % of the total sample) tHcy level was greater than 12 µM, thus a modest HHcy was observed. In 29 patients (50,9 % of the patients tested for ibrinolysis capacity) the activation of intravascular coagulation was combined with hypoibrinolysis, and the frequency of HHcy in this group reached 58,6 %. A strong correlation between the time of ibrinolysis and tHcy concentration was found (Rs = 0,564, p = 0,0001).Conclusion. Thus, it appears that moderate HHcy is not only one of the risk factors for the activation of intravascular coagulation, but also causes inhibition of ibrinolysis in this pathology.
PECULIARITIES OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION IN PATIENTS WITH ESSENTIAL HYPERTENSION
Authors: Libis R. A. , Dushina A. G. , Oleynik E. A. 
Published: December 2018

Objective. To estimate clinical status, quality of life (QOL), physical activity, structural and functional pe- structural and functional penal peculiarities of the heart in patients with chronic heart failure with preserved ejection fraction (CHF-PEF).Design and methods. Seventy-two patients with CHF-PEF (age 47–77 years) were examined. Clinical status, QOL by Minnesota questionnaire, 6-minute walk test, heart ultrasound, serum N-terminal brain natriuretic propeptide level were assessed in all patients.Results. Main complaint was dyspnea at physical activity in patients with CHF-PEF (95,8 %). Structural and functional myocardium changes were more expressed in patients with higher functional class. General total score by Minnesota questionnaire was 21,5 [14,5; 40,0] in men and 48,5 [36,0; 59,0] in women. Tolerance to physical activity influenced QOL.Conclusions. All patients had echocardiographic signs of left ventricular diastolic dysfunction. The higher functional class of heart failure was associated with the more pronounced myocardial hypertrophy, decreased QOL and physical activity. QOL was higher in men, than in women. Diabetes mellitus, ischemic heart disease were associated with the clinical progression of CHF.
Patterns of alcohol, tobacco, and illicit drug use among transsexuals
Authors: Gómez-Gil Esther , Simulionyte Egle , Balcells-Oliveró Mercè , Valdés Manuel , Salamero Manel , Guillamón Antonio , Esteva Isabel 
Published: December 2018

This study evaluated the patterns of substance use in a large sample of male-to-female (MtoF) and female-to-male (FtoM) transsexuals. A total of 251 transsexual subjects (163 MtoF and 88 FtoM), attended in the Catalonia Gender Unit, completed self-administrated questionnaires on consumption of alcohol, tobacco, cannabis, cocaine, opioids, and designer drugs. Results were compared with the general population in Catalonia using data from the National Health Service (EDADES 2013 study). Current consumption of alcohol (70.1%), tobacco (46.2%), and cannabis (16.3%) among transsexuals was similar when compared with men (72.1%, 42.1%, 12.8%) and increased when compared with women (57.6%, 35.2%, 5%); the consumption between MtoF and FtoM subgroups was similar. The use of cocaine was almost ten times more prevalent in the MtoF subgroup than in the FtoM subgroup (1.1%), and in general population (less than 1%). Only a few reported uses of opioids and designer drugs. In conclusion, the substance use among transsexuals, except for the use of cocaine, was similar between MtoF and FtoM subgroups, and resembled the consumption prevalence among men in the general population. The proportion of cocaine consumers in the MtoF subgroup was up to ten times higher than in other subgroups.
JUDGE’S DECISION ON WORK TERMINATION DISPUTE IN INDONESIA AFTER CONSTITUTIONAL COURT DECISION NUMBER 37/PUU-IX/2011
Authors: Madjid Neni Vesna , Isra Saldi , Warman Kurnia , Mardenis Mardenis 
Published: December 2018

Testing the provision of Article 155 section (2) Law Number 13 of 2003 on Manpower has been decided by the Constitutional Court (CC) through decision Number 37/PUU/IX/2011. Prior to the Constitutional Court decision, there are many various interpretations of undetermined clause. The Constitutional Court firmly states that the undetermined clause must be interpreted as “having a permanent legal force ".This study aims to analyze how the judges dismissed dispute of work termination cases in Indonesia after the decision. The research applied juridical normative method by using secondary data literature such as legal documents, previous studies and other references which are relevant to the judges' decision within the Supreme Court after the Constitutional Court decision. Based on the analysis temporary result, the judges within the Supreme Court in 3 regions (Padang, Pekanbaru and Jakarta Pusat) and the Supreme Court itself are not practically guided by the Constitutional Court decision. It obviously results in the lack of legal certainty for the parties, especially workers.Keyword: Constitutional Court, Industrial Relation Court, Interpretation, Supreme Court.
APLIKASI MODEL EPIDEMIK SEIAR-SEI PADA PENYEBARAN PENYAKIT MALARIA DENGAN INFEKSI ASIMTOMATIK DAN SUPER INFEKSI
Authors: Belwawin Stella Maryana 
Published: December 2018

AbstractThis aim of this study is to determine the point of equilibrium and analyze the stability of SEIAR-SEI model on malaria disease with asymptomatic infection, super infection and the effect of the mosquito's life cycle. This study also aim is to measure the sensitivity of the spread of malaria to the parameters of asymptomatic infections, the rate of treatment, and the rate of birth of mosquitoes through the magnitude of . The method in this research is deductively, through several stage, such as determination of disease-free equilibrium point and endemic equilibrium point, determination of basic reproduction number (), analyze of the basic reproduction number sensitivity of the spread of malaria to the parameters of asymptomatic infections, the rate of treatment, and the rate of birth of mosquitoes. The endemic equilibrium point was obtained using rule of Descartes. The result show that the change in the value of parameter , , and has effect on the basic reproduction number (). Treatment factors in the human population influence the elimination of malaria in a population. Whereas asymptomatic infection factors and the birth rate of adult mosquitoes influence the increase in malaria infection. Keywords: Malaria, asymptomatic infection, super infection, basic reproduction number, rule of descrates. AbstrakPenelitian ini bertujuan menentukan titik keseimbangan dan menganalisis kestabilan dari model SEIAR_SEI pada penyakit malaria dengan pengaruh infeksi asimtomatik, super infeksi, dan siklus hidup nyamuk. Penelitian ini juga bertujuan mengukur tingkat sensitivitas penyebaran penyakit malaria terhadap parameter infeksi asimtomatik, laju pengobatan, serta laju kelahiran nyamuk.melalu besaran . Metode yang digunakan dalam penelitian ini adalah metode deduktif dengan langkah-langkah : menentukan titik keseimbangan bebas penyakit dan endemik dan menentukan bilangan reproduksi dasar ). Analisis sensitivitas bilangan reproduksi dasar dilakukan terhadap parameter infeksi asimtomatik, pengobatan, dan laju kelahiran nyamuk. Tititk keseimbangan endemik diperoleh dengan aturan descrates. Hasil yang diperoleh menunjukkan parameter , , dan berpengaruh terhadap bilangan reproduksi dasar (). Faktor pengobatan berpengaruh terhadap eliminasi penyakit malaria. Sedangkan faktor infeksi asimtomatik dan laju kelahiran nyamuk dewasa berpengaruh terhadap peningkatan infeksi penyakit malaria. Kata kunci: Malaria, Infeksi Asimtomatik, Super Infeksi, Bilangan Reproduksi Dasar, Aturan Descrates .
Applications of the Generalized Kummer’s Summation Theorem to Transformation Formulas and Generating Functions
Authors: Atash Ahmed Ali , Bellehaj Hussein Saleh 
Published: December 2018

Abstract
In this paper, we establish two general transformation formulas for Exton’s quadruple hypergeometric functions K
5 and K
12 by application of the generalized Kummer’s summation theorem. Further, a number of generating functions for Jacobi polynomials are also derived as an applications of our main results.
Core Competencies and a Workforce Framework for Community Health Workers: A Model for Advancing the Profession
Authors: Covert Hannah , Sherman Mya , Miner Kathleen , Lichtveld Maureen 
Published: December 2018

Objectives. To establish a validated, standardized set of core competencies for community health workers (CHWs) and a linked workforce framework. Methods. We conducted a review of the literature on CHW competency development (August 2015), completed a structured analysis of literature sources to develop a workforce framework, convened an expert panel to review the framework and write measurable competencies, and validated the competencies (August 2017) by using a 5-point Likert scale survey with 58 participants in person in Biloxi, Mississippi, and electronically across the United States. Results. The workforce framework delineates 3 categories of CHWs based upon training, workplace, and scope of practice. Each of the 27 competencies was validated with a mean of less than 3 (range = 1.12–2.27) and a simple majority of participants rated all competencies as “extremely important” or “very important.” Conclusions. Writing measurable competencies and linking the competencies to a workforce framework are significant advances for CHW workforce development. Public Health Implications. The standardized core competencies and workforce framework are important for addressing health disparities and maximizing CHW effectiveness.
Equipping Public Spaces to Facilitate Rapid Point-of-Injury Hemorrhage Control After Mass Casualty
Authors: Goolsby Craig , Strauss-Riggs Kandra , Rozenfeld Michael , Charlton Nathan , Goralnick Eric , Peleg Kobi , Levy Matthew J. , Davis Tim , Hurst Nicole 
Published: December 2018

In response to increasing violent attacks, the Stop the Bleed campaign recommends that everyone have access to both personal and public bleeding-control kits. There are currently no guidelines about how many bleeding victims public sites should be equipped to treat during a mass casualty incident. We conducted a retrospective review of intentional mass casualty incidents, including shootings, stabbings, vehicle attacks, and bombings, to determine the typical number of people who might benefit from immediate hemorrhage control by a bystander before professional medical help arrives. On the basis of our analysis, we recommend that planners at public venues consider equipping their sites with supplies to treat a minimum of 20 bleeding victims during an intentional mass casualty incident.
Law Enforcement Agencies’ Perceptions of the Benefits of and Barriers to Temporary Firearm Storage to Prevent Suicide
Authors: Brooks-Russell Ashley , Runyan Carol , Betz Marian E. , Tung Greg , Brandspigel Sara , Novins Douglas K. 
Published: December 2018

Objectives. To examine the perceived benefits of and barriers to law enforcement agencies providing increased access to voluntary and temporary firearm storage. Methods. We surveyed 448 police chiefs and sheriffs in 8 US Mountain West states about firearm storage practices, benefits of and barriers to storage, and related attitudes and beliefs. Data collection occurred during the spring and summer of 2016. Results. Nearly three quarters of agencies reported that they are already providing storage and perceive relatively few barriers in doing so. Agency characteristics were not associated with current provision of firearm storage. Among the barriers identified included state laws, limited space, training needs, and community perceptions. Benefits of storage included being perceived positively by the community and supporting health care workers. Conclusions. Engaging with law enforcement agencies in suicide prevention efforts and addressing their perceived barriers to providing temporary firearm storage have promise as part of a comprehensive suicide prevention approach.
How Close is too Close? Well Spacing Decisions Come With Risks
Authors: Rassenfoss Stephen 
Published: December 2018

There is no formula for properly spacing wells in unconventional plays. When a reservoir consultant recently described conversations with clients about how many wells they could drill per acre, it sounded like a doctor advising a patient considering back surgery.
“I am not trying to tell you what your spacing should be,” said Miles Palke, management senior vice president for Ryder Scott, adding that the modeling and production history matching his company offers is “a process to help you inform your decision.”
The cautious approach was understandable in his talk at the recent SPE Hydrocarbon Economics and Evaluation Symposium. Well-spacing decisions are increasingly tricky because of the potential downsides, from damaging hits to older parent wells to production from new child wells falling short of the old wells.
A recent technical paper authored by Schlumberger (SPE 191799), based on data from the Wolfcamp shale play in the Permian’s Delaware Basin, found that when a new well is drilled within 1,000 ft of an older well, the older parent well outperformed the child well 66% of the time. When the results were adjusted for the bigger, more expensive completions now common, 79% of the older wells performed better.
It is getting harder to avoid the issue of well spacing. In its recent earnings call with investment analysts, Schlumberger said that 70% of the wells drilled in the Eagle Ford are infill wells, as are 50% of those wells drilled in the Permian.
While there is a lot of agonizing about fracs hits when wells are closely spaced, wider spacing also has its risks. Schlumberger predicted that even when the wells are 2,000–2,500 ft apart, the parent wells perform better 61% of the time when the production was adjusted for the larger volumes of proppant per foot now commonly used. As wells get farther apart, there is a growing chance that productive rock in between will never be stimulated.
Well interactions are a constant reminder that fracturing does not create networks of producing fractures shaped like shoe boxes that can be lined up neatly on a shelf. Fracturing the maximum volume of a reservoir requires dealing with the contact that comes when wells with irregularly shaped fracture networks are located side by side.
“People talk about well interference and bring it up as if it is a bad thing,” said Erdal Ozkan, SPE’s reservoir technical director. The petroleum engineering professor at Colorado School of Mines added that overlapping production “has always existed between two wells in the same field. There will be interference. If you reduce the drainable area, you reduce productivity of each well.”
Fewer Grads + More Jobs: A Winning Formula for Job Hunters
Authors: Rassenfoss Stephen 
Published: December 2018

The 2019 graduating class of petroleum engineers will mark the last gasp of a boom before a steep drop in the size of future graduating classes coming out of US universities.
After a class of nearly 2,000 petroleum engineering graduates next spring, the graduation rate over the next 3 years will fall to less than 1,000 per year, according to an annual survey of US petroleum engineering programs by Lloyd Heinze, a professor at Texas Tech University. The survey includes primarily US universities. The numbers are a direct reflection of the sharp downturn in oil prices that began in 2014 and caused large downsizing among oil and gas operators and service companies.
For young engineers looking for jobs after college, it represents a welcome change from the rocky job market faced by graduates after the industry switched into job-cutting mode. For employers used to having their pick of the top students since the bust began in 2015, it could mean being one of several bidders for a shrinking pool of graduates.
Professors on campuses are seeing signs of improvement, but they caution that the evidence is more anecdotal than numerical.
“A good number of seniors have jobs and a lot do not. One thing is that it is a big senior class,” said Karsten Thompson, department chair for the petroleum engineering program at Louisiana State University (LSU). It is too early for hard numbers but “there are more companies on campus with more students having internships and job offers.”
“Internships went quite well this year. It looks like the recovery is under way. Students are much more comfortable,” said Erdal Ozkan, a professor at Colorado School of Mines.
The job market is much improved, said John Lee, a professor at Texas A&M who also sees improved internship opportunities.
Graduating Boomers
The class of 2019 is made up of the last big crop of freshman enrolled back in the fall of 2014 when the bust killed the assumption that $100/bbl oil was a given. The nearly 2,000 seniors in the 2018–2019 class is considerably smaller than the past two, which exceeded 3,200, but it is double the size of three classes that follow.
Texas Tech has 77 seniors now, compared with a peak total of 227 in 2014, and only 43 juniors following them. The junior class is 80% lower than the 2015 peak. That drop is an indication of Texas Tech’s decision not to limit petroleum engineering enrollment during the boom—only a few schools including Texas A&M and the University of Texas capped enrollment—and the quick reactions of a “population of students and parents who were faster to realize the downturn” because so many live in West Texas where the industry is all around them.
Between the boom in the early 1980s—where schools provided a generation’s worth of exploration and production professionals—and the recent boom that produced many more grads, was a long, deep slump.
Technology Focus: Mature Fields and Well Revitalization (January 2019)
Authors: Marathe R. V. 
Published: December 2018

Technology Focus
Mature brownfields contribute significantly to global oil production. A study of the papers presented during the past year at various SPE conferences reveals a continuation of the trend to put in massive effort to minimize decline from mature brownfields. This has been attempted through several means, such as improving well integrity and judicious well interventions to restart production from idle wells. One paper discusses a conceptual platform where all stakeholders (operator and service providers) can share and formulate a win/win strategy wherein operational efficiency and success rate of an activity are the main drives.
As an offshoot of such well-intervention activities, low-resistivity pay zones, either shallower or deeper with respect to the main pay and hitherto considered unattractive, have been identified and contribute significantly in sustaining production decline. There is an all-around emphasis on characterizing highly compartmentalized and difficult reservoirs that have thin reservoir sands defying well-to-well correlations because of a lack of marker shales. In some cases, the presence of conductive minerals such as pyrites or siderites further masks the presence of hydrocarbons in conventional log analysis.
In addition to efforts on improved reservoir characterization, optimizing ongoing waterfloods is an area where focused efforts are yielding rich dividends. These involve locating the bypassed oil and addressing unswept areas through reservoir surveillance and modeling. Some operators also have focused on innovative enhanced-oil-recovery techniques in mature brownfields to enhance production.
Recommended additional reading at OnePetro: www.onepetro.org.
SPE 186362 Extending Life of Liquid-Loaded Gas Wells Using Velocity-String Application: Case Study and Candidate Selection by Satria Andrianata, VICO Indonesia, et al.
SPE 188443 Novel Reservoir-Modeling and Experimental-Design Approach To Tackle the Challenge of Modeling Highly Compartmentalized Reservoirs Under Large Uncertainties in a Mature Offshore Field, Malaysia by A. Sulaksana, Sabah Shell, et al.
SPE 188770 Fluid-Front Monitoring Using Smart and Safe Pulsed-Neutron Technology on Slickline by Rahul Grover, Schlumberger, et al.
Managed-Pressure-Drilling Equipment Augments Deepwater Well Control
Authors: Carpenter Chris 
Published: December 2018

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 186331, “Augmenting Deepwater Well Control With Managed-Pressure-Drilling Equipment,” by Austin Johnson, SPE, Brian Piccolo, Henry Pinkstone, SPE, Bo Anderson, and Justin Fraczek, SPE, AFGlobal, prepared for the 2017 SPE/IATMI Asia Pacific Oil and Gas Conference and Exhibition, Bali, Indonesia, 17–19 October. The paper has not been peer reviewed.
This paper describes how a technique known as applied-surface-backpressure managed-pressure drilling (ASBP-MPD) can alleviate the limitations of conventional deepwater well control. The paper discusses equipment design and operating philosophy, outlining actions that can be taken to respond to an influx while remaining within the primary well barrier.
Conventional Well Control: Background and Limitations
Industry personnel are trained to follow conventional well-control-response steps when securing a well and closing a subsea blowout preventer (SSBOP) once an influx is detected. The steps are logical from the perspective of adhering to the operating requirements of existing well-control equipment. While variations in procedures exist between companies, the logic behind these steps remains consistent across the industry. The conventional steps are as follows:
Stop rotating; pick up off bottom and space out
Stop the mud pumps
Conduct a static flow check
Close the SSBOP
Conventional well-control response is limited by the design and operating philosophy of conventional well-control technology. The challenges associated with these constraints include a significant drop in bottomhole pressure (BHP), increased influx volume before the well is finally secured, and the amount of time needed to detect an influx. The initial confirmation of an influx can take a substantial period of time because of a variety of factors that can influence the return flow rate and mud-pit volumes.
On a deepwater rig, the interpretation of pit-volume and flow-rate changes can be subjective. To complicate matters further, conventional drilling rigs often are equipped only with inaccurate paddle flowmeters on the main flowline to measure flow out of the well; these do not offer a precise flow measurement.
The conventional well-control-response procedure does not seem adequate for the deepwater drilling environment when evaluated in terms of influx detection and response time, total influx volume, and reservoir drawdown. Furthermore, after the SSBOP is closed, the conventional well-control response is subject to significant residual risks in the form of stuck pipe, lost circulation from chokeline friction, and the exceeding of kick tolerance. Finally, closing the SSBOP does not address an influx that has been circulated into the riser undetected.