bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigations on the prevalence of tortoise picorna-virus in captive tortoises in Germany
Authors: Funcke Svenja , Lierz Michael , Paries Susanne 
Published: December 2018

Summary
Objective: Tortoise picornavirus (ToPV) has been speculated to play an important role in the frequently seen disease pattern of juvenile shell softening. This study aimed to determine ToPV prevalence among German tortoise collections. Material and methods: A total of 334 animals selected from 27 different collections were included. Seven species of four genera of the family Testudinidae (Testudo graeca, T. hermanni, T. marginata, T. horsfieldii, Centrochelys sulcata, Stigmochelys pardalis, Chelonoidis carbonarius) were sampled. The tortoises were clinically investigated and none of the adults showed any signs of shell softening. Seven hatchlings of a ToPV-positive T. graeca breeding pair showed retarded growth and a progressive shell weakness that resulted in death. Each animal was sampled by conjunctival, pharyngeal and cloacal swabs (990 swabs in total) and blood sampling (293 in total). All three swabs of one animal were pooled and tested by reverse transcriptase polymerase chain reaction (RT-PCR) for tortoise picornavirus RNA. Blood samples were investigated by virus neutralisation test (VNT) for specific anti ToPV antibodies. All titres equal to or higher than log2 = 2 were considered positive. Results: In total, 35 adult and 11 juvenile animals were tested positive for ToPV RNA. The serological investigation did detect specific antibodies against ToPV in 44 adult tortoises and one juvenile. In total, 76 animals were tested positive in either one of the investigations, 16 animals in both. The highest number of ToPV-positive animals was found for T. graeca, with a prevalence of 32 %. No specimens of C. carbonarius, C. sulcata, or S. pardalis were tested positive. Conclusion and clinical relevance: The results propose a predisposition in T. graeca, as well as a high prevalence of ToPV in T. graeca, whereas other species showed only single or no positive animals, but may function as virus carriers.
Cobalaminmangel bei Hund und Katze
Authors: Toresson Linda , Spillmann Thomas , Hanisch Franziska 
Published: December 2018

ZusammenfassungCobalamin ist ein Vitamin der B-Gruppe und als Kofaktor an Stoffwechselabläufen wie der Nukleinsäuresynthese, der Aminosäuresynthese und dem Zitratzyklus beteiligt. Da Säugetiere Cobalamin nicht selbst synthetisieren können, sind sie auf die Zufuhr über die Nahrung angewiesen. Die Resorption des Vitamins setzt bei Hund und Katze ein funktionales exokrines Pankreas voraus. Sie erstreckt sich über Magen und Duodenum bis hin zum Ileum und stellt einen äußerst komplexen Prozess dar. Somit kann eine Fülle gastrointestinaler Erkrankungen wie z. B. chronische Enteropathien, intestinales Lymphom oder exokrine Pankreasinsuffizienz zur Hypocobalaminämie führen. Ferner wurde bei einigen Hunderassen (Riesenschnauzer, Border Collie, Australian Shepherd und Beagle) ein primärer, hereditärer Cobalaminmangel (Imerslund-Gräsbeck-Syndrom) nachgewiesen. Zu den klinischen Sympto men einer Hypocobalaminämie zählen Inappetenz, Erbrechen, Diarrhö, Wachstumsstörungen und neuronale Defizite. Als labordiagnostische Veränderungen wurden nichtregenerative Anämie, Leukopenie, Hypoglykämie und Hyperammonämie beschrieben. Bei Verdacht auf einen Cobalaminmangel wird die Vitaminkonzentration bei Hund und Katze üblicherweise mittels Immunoassay im Blut gemessen. Da jedoch Blut- und Zellgehalt des Vitamins differieren können, ist die isolierte Cobalaminmessung in ihrer Aussagekraft limitiert. Die Therapie hängt in erster Linie von der Primärerkrankung ab und hat zum Ziel, die Ursache der Hypocobalaminämie zu beseitigen. Oftmals zeigt sich ein Behandlungserfolg der gastrointestinalen Erkrankung allerdings erst dann, wenn zusätzlich parenteral oder oral Cobalamin verabreicht wird. Bei Patienten mit Imerslund-Gräsbeck-Syndrom ist die regelmäßige und lebenslange Substitution essenziell.
İŞ TATMİNİ BOYUTLARININ İŞ GÜVENLİĞİ UZMANLARI VE İŞYERİ HEKİMLERİ AÇISINDAN KARŞILAŞTIRMASI: AHP UYGULAMASI
Authors: GÜNAY Ziya 
Published: December 2018

Çalışanların yaptıkları işten doyum
sağlamaları hem çalışanların iş ve özel yaşamları hem de örgüt ve toplum
açısından önemlidir. Yaptığı işten tatmin olmayan çalışan bireysel örgütsel ve
toplumsal bir kısım kayıpların yaşanmasına sebep olmaktadır. Çalışanlar işin
bir yönünden tatmin olurlarken diğer yönünden tatmin olmayabilirler. İş
tatmininin her bir boyutunun çalışanların genel iş tatmini boyutuna etkisi
farklı olabilir. Bu bakımdan iş tatminin boyutlarının çalışanlar için öneminin
ortaya çıkarılması işverenler ve araştırmacılar için iş tatminin anlaşılmasında
ve çalışanların motive edilmesinde yol gösterici olabilir. Bu
çalışmanın amacı Bursa ilinde Ortak Sağlık ve Güvenlik Birimleri’nde (OSGB) çalışan
iş güvenliği uzmanlarının ve işyeri hekimlerinin iş tatmini boyutlarına
verdikleri önemi ortaya koymaktır. Araştırmada AHP kullanılarak iş tatmini
boyutlarının önem düzeyleri belirlenmiştir. Araştırmadan elde edilen sonuçlara
göre hem iş güvenliği uzmanları hem de işyeri hekimleri için çalışma
arkadaşları iş tatminin en önemli boyutunu oluşturmaktadır. Ancak C sınıfı iş
güvenliği uzmanları için ücret iş tatmini açısından en önemli boyuttur. Bu
sonuç aynı meslek grubu içinde farklı statülerin iş tatmini boyutlarına farklı
yaklaşımlarının olabileceğini göstermektedir. Araştırmanın sonucuna göre iş
güvenliği uzmanları ve işyeri hekimleri için çalışma arkadaşları iş tatminin en
önemli boyutunu oluşturmaktadır.
A Spiraea media Fr. Schm. Balaton-felvidéki előfordulásáról
Authors: Varga Szabolcs , Sinigla Mónika , Bauer Norbert 
Published: December 2018

A Spiraea media Balaton-felvidéki előfordulása növényföldrajzi szempontból nagy jelentőségű adat, de a populáció pontos helye, mérete és élőhelye a közelmúltig ismeretlen volt. A fel­sőörsi Kopasz-hegyen a közelmúltban megtalált Spiraea media populáció atipikus élőhelyen, egy vi­szonylag zárt cseres-tölgyes erdőben (~Fraxino orni-Quercetum cerridis) található. Egyedeinek virágzá­sa – és a faj megtalálása – feltehetően a szomszédos erdőrészlet letermelése következtében kialakult fénytöbbletnek köszönhető. A 19. századi katonai térképek alapján feltételezhető, hogy a terület koráb­bi vegetációjában jelen lehettek a faj számára kedvezőbb, fényben gazdag sziklás gyep-cserjés-erdő mozaikok, akár sziklai cserjések is.
A potenciálisan inváziós vesszős aggófű (Senecio inaequidens DC.) aktuális elterjedése
Authors: Haszonits Győző , Schmidt Dávid 
Published: December 2018

Munkánkban a dél-afrikai eredetű, hazánkban potenciális özönnövénynek számító Senecio inaequidens magyarországi előfordulási adatait foglaljuk össze, valamint beszámolunk néhány újabb hazai megtelepedéséről. Irodalmi, herbáriumi, illetve saját adatokat összegeztünk, valamint ak­tu­a­li­záltuk a faj elterjedési térképét. Szemléltetjük a faj inváziójának aktuális stádiumát és a termé­szet­kö­zeli élőhelyekre jelentett lehetséges veszélyeit.
Results of studying disinfectant-resistance of bacteria, excreted from patients in microbiological provision of epidemiological surveillance of hcai at multitype medical institution
Authors: Nesterova D. D. , Neshataev A. N. , Lukyanenko N. V. , Petrova A. A. , Prokopyev V. V. , Sergeev T. S. 
Published: December 2018

Aim. To improve microbiological monitoring of disinfectant-resistance of microorganisms, excreted from clinical material in epidemiological surveillance of HCAI.
Materials and methods. Over the period from 2012 to 2016, while conducting resistance monitoring, 3320 investigations of clinical material were performed. The number of studied microorganisms was 1557. The number of excreted disinfectant-resistant microorganism strains was 337. The studies of microorganisms from clinical material for resistance were realized to 48 disinfectants of 15 groups with different reactants.
Results. During the present study it was established that microbiological monitoring, oriented for continuous monitoring of microorganisms circulation will permit to increase the number of studies in 2016 by 2.6 times, to reduce the total number of disinfectant-resistant flora in 2016 by 62 %. The greatest weight of excreted cultures was in the units of surgical profile – 48.8 %, resuscitation profile – 30 %, therapeutic one – 21.2 %. Clinical material, from which positive results were obtained, was determined by scourage (from 43.5 % in the surgical unit to 74.8 % in therapeutic), blood sterility (from 2.7 % in therapeutic units to 31.4 % in resuscitation units). Microflora, excreted from clinical material is presented predominantly by P. aeruginosa – 24.0 %, Kl. pneumoniae – 30.0 %, E. coli – from 12.9 to 22.1 %, St. aureus – from 3.0 to 7.6 %. The studies regarding disinfectant-resistance to 48 items from 15 groups of chemical compounds are the evidence of growing resistance to QAC, including QAC + amines – 24.7 %, QAC + aldehyde-containing – 6.8 %, chlorine-containing – 21.9 %. The highest resistance to disinfectants used was in Acinetobacter spp., Kl. pneumoniae, P. aeruginosa, E. coli.
Conclusions. The developed algorithm of microbiological study, based on software, permitted to form the database, to monitor epidemiologically significant microorganisms and correct choice of disinfectants and disinfection tactics.
Personified approaches to organization of risk-oriented medical observation in conditions of opportunistic-pathogenic microbial air contamination of working zone
Authors: Masyagutova L. M. , Gizatullina L. G. , Vlasova N. V. , Khairullin R. U. , Sadrtdinova G. R. , Bakirov A. B. 
Published: December 2018

Aim. To ground the personified approaches when organizing risk-oriented medical observation of animal breeding workers.
Materials and methods. The total capillary blood analysis with calculation of percentage of peripheral blood cellular composition was carried out, allergization index (AI) and immunoreactivity index (IRI) was assessed, the total number of microorganisms per 1 m3 of the air in the working zone was determined, the total microbial count (TMC) was calculated.
Results. The standard periodic medical examination of workers is sufficient with TMC value less than 500 CFU/m3, absence of chronic infectious inflammatory diseases (CIID), AI value less than 1.08 standard units, IRI value less than 13 standard units. When having a mean level of microbiological risk, CIID detection ranging from 1 to 3, AI value less than 1.08 and IRI value less than13 standard units, it is recommended to add a survey to the previous stage, using special questionnaire (attitude to work, working conditions, fatigability degree, susceptibility to allergy etc.). When having TMC value more than 2500 CFU/m3, CIID detection from 4 to 5, AI value 1.08–1.3 standard units, IRI value 13.1–15.7 standard units, an additional study of the upper airways microflora as well as immune status using tests of the first level should be realized; further recommendations on treatment-and-preventive measures in outpatient conditions should be given; with TMC value more than 5000 CFU/m3, presence of CIID – 6 and more, AI value 1.4–1.5 standard units, IRI value 15.8–18.3 standard units, it is recommended to perform immunological studies using tests of the second level with determination of susceptibility to antimicrobial preparations in hospital conditions of Occupational Pathology Center.
Conclusions. The method of personified risk-oriented medical observation of persons, working in animal breeding is offered.
Influence of non-motor manifestations of Parkinson’s disease on quality of life
Authors: Khegai O. V. , Selyanina N. V. , Karakulova Yu. V. 
Published: December 2018

Aim. To estimate the degree of influence of non-motor manifestations on the quality of life among patients with Parkinson’s disease.
Materials and methods. In the study, the “case-control” design was used, processing of the data was conducted with nonparametric methods. Complex examination of 58 patients with Parkinson’s disease was performed. The control group included 15 healthy persons.
Results. Manifestation of cognitive, anxiety-depressive, vegetative symptoms in the main group was significantly higher than in the control. There was revealed a negative correlation dependence between the general manifestation of vegetative disorders and the social functioning indices (R = – 0.5; p = 0.001), pain intensity (R = – 0.5; p = 0.001) and psychical health (R = – 0.5; p = 0.005) that proves aggravation of the data on health components as the severity of symptoms was growing. The analyzed vegetative disorders of separate subsystems demonstrated the analogous tendencies. Severity of depressive symptoms influences the pain indices (R = – 0.4; p = 0.01) and the social functions (R = – 0.3; p = 0.03). According to unified scale, non-motor symptoms negatively influence the general health status (R = – 0.3; p = 0.001), social functioning (R= – 0.23; p = 0.004), pain assessment (R = – 0.5; p = 0.001).
Conclusions. Non-motor symptoms aggravate the quality of life, influencing both physical and psychological component of health. The absence of correlation between the duration of therapy and the severity of non-motor symptoms confirms the independence of this block of symptoms.
Optimized use of eight-arm maze when studying effect of preparation “Cycloferon®” on cognitive potential of experimental animals
Authors: Kuznetsov S. V. , Kuznetsov V. F. , Makunina E. V. , Kasimova R. M. , Tyutyunschikova V. D. , Obernebesova T. P. 
Published: December 2018

Aim. To develop the testing algorithm in conditions of radial eight-arm maze and to study the effect of preparation “Cycloferon®” on cognitive processes in experimental animals in conditions of repeated training.
Materials and methods. The study was conducted on experimental animals – white outbred male rats (n = 21) aged 8–9 months using the original method. “Radial eight-arm maze” was used as experimental laboratory device. During the experiment, to activate searching behavior, daily nutrition regime was reduced by 15–20 %. To fortify, milk product “Thickened milk” was used. At the first experimental stage, the animals received a typical vivarium ration. During the second part of this study, the rats underwent repeated training after taking “Cycloferon®”, calculated for each rat by the mass – 0.77 mg per 100 g of the animal body mass; after that the rats’ spatial memory was assessed.
Results. Taking into account the results of the second part of experiment, statistically significant tendency to increase was revealed among animals with positive result of testing with one-sided Fisher criterion (p = 0.037). No correlation between taking “Cycloferon®” and the number of repeated entering of the arms and the total number of entering of the arms was detected (p > 0.05) that proves the formation of purposive movement.
Conclusions. A reliable tendency to increase in the number of animals, trained during the repeated testing against the background of using “Cycloferon®”, which possesses immunomodulating effect as well as antioxidant action, confirms the actuality of applying the offered method while studying cognitive effect of substances, requiring long-term introduction.
GEMİ VE LİMAN ETKİLEŞİMİ İÇİN ÖNERİLEN ENERJİ YÖNETİM SİSTEMİ MODELİNİN İNCELENMESİ
Authors: YİĞİT Kenan , ACARKAN Bora 
Published: December 2018

Bu çalışmada, yeni
nesil gemi ve liman tasarımı konseptlerine uygulanabilecek ve gemilerin limanda
iken alternatif enerji kaynaklarını kullanarak elektrik enerjisi ihtiyacının
karşılanmasına imkân tanıyacak bir enerji yönetim modeli önerilmiştir. Bu model
ile gemiler limandaki operasyonlarını gerçekleştirirken finansal ve çevresel
şartları göz önüne alarak hem kendi jeneratörlerini kullanabilecek hem de
ulusal şebekeye etkin bir şekilde bağlanabilecektir. Bu sayede, gemi
mürettebatı bulunduğu limanda uluslararası sözleşmelerden kaynaklı çevresel bir
kısıtlama var ise bu kuralları karşılamak için en temiz enerji kaynağını
seçebilecektir. Çevresel kısıtlamaların karşılandığı bir limanda ise en
ekonomik enerji kaynağını kullanarak enerji maliyetlerinde tasarruf
sağlayabilecektir.

Çalışmada, gemi
enerji yönetim modeli ve benzetim çalışması için MATLAB programı kullanılmıştır.
Benzetim çalışmasında, kabul edilebilir sonuçlar elde etmek için “M/V İnce Hamburg” isimli yük
gemisine ait veriler ile Türkiye ulusal şebekesine ait gerçek veriler dikkate
alınmıştır. Sadece kendi jeneratörlerini kullanan gemi ile enerji yönetim
sistemine sahip ve ulusal şebekeye bağlanabilen gemi için elde edilen sonuçlar karşılaştırılmıştır.
Sonuçlar, önerilen sistem ile enerji maliyetinde yaklaşık %46’lık bir tasarruf,
CO2 salımında ise yaklaşık
%33’lük bir azalma sağlanacağını göstermektedir.
Arabic Sign Language Adaptation In Teaching Fardhu Ain To The Disabled Hearing
Authors: Mohd Rashid Syar Meeze , Mohd Yasin Mohd Hanafi , Ashaari Noraidah Sahari 
Published: December 2018

The purpose of this study is to review the consensus of experts in the adaptation of the use of sign language in teaching fardhu ain to the disabled hearing. This study has used the technique of fuzzy delphi to seek a consensus of experts skilled in sign language to answer the review questions. Distributed instruments includes 14 items in order to obtain a consensus of experts. The findings show that there are five items that need to be adopted in the Arabic sign language that is the sign language related to the pronouncement of the Shahadah, beliefs and tenets of islam, body cleanliness, the aurat and prayer with the deffuzification value of 0.767.
Analisa Gangguan Motor Close Cycle Cooling Water Pump (Cccwp ) #A Steam Turbin Menggunakan Vib Xpert Di Pltgu Grati
Authors: Romadhoni Moch Avif , Jamaaluddin Jamaaluddin 
Published: December 2018

PT Indonesia Power UPJP Perak Grati is the one state-owned enterprice (BUMN) which operates on an electricity power generation so that needed same assistance equipment for anufacturing, a 6 Kv induction motor, need to do a maintenance periodically for keeping the accomplishment. The author wrote te thesis to analize the motor disturbance Close Cycle Cooling Water Pump (CCCWP) #A Steam Turbine in order that there is no the suddenly disturbance in the motor equipment so that make the accomplisment of cooler system steam turbine disturbed. The method which doing the taking same data for motor vibration noise using vibxpert whict can analize the result and taking same data using motor current signature analysis (MCSA) functioned for analyzing the disturbed of the current and voltage. Based on the result, it can be concluded that vibrasi noise increase periodicly from bearing motor side there is a current data different becaused the outer part motor so that need doing a maintenance strategy so that the equipment remains reliable to operate.
Comparison of Two Different Shapes of Stylets for Intubation with the McGrath MAC®: A Randomized Controlled Trial
Authors: Lim Hyun-Young , Lee Mi-Suk , Ryu Kyoung-Ho , Lee Sung Hyun , Cho Eun-Ah 
Published: December 2018

Abstract
Background: Adequate shapes for videolaryngoscopes are important for safer, faster, and successful intubation. The aim of this study was to compare two different shapes of stylets, the 60º and J-shape stylets, for intubation with the McGrath MAC®.
Methods: In this multicenter, prospective, randomized controlled study, patients undergoing elective surgery under general anesthesia were randomly assigned into the 60º group or the J group. After anesthetic induction, subjects in both groups were intubated with an endotracheal tube bent into a specific shape according to the group allocation. Time to intubation, difficulty of intubation, glottic view grade, use of external manipulation, and number of intubation attempts were recorded.
Results: One hundred and eight patients in the J group and 110 patients in the 60º group were enrolled. Time to intubation in the J group [23.1 (20.6-28.0)] was not different from the 60º group [24.8 (20.5-28.3), P = 0.623). There were no differences in difficulty of intubation, glottic view grade, use of external manipulation, and number of intubation attempts between the two groups.
Conclusions: Adding extra curvature to the tube to resemble the shape of the blade did not improve the intubation conditions of the McGrath MAC®.
The Effect of Oral Pregabalin on Epidural-Induced Shivering and Epidural Characteristics in Gynecological Surgeries, a Prospective Randomized Double-Blind Study
Authors: Menesy Tarek Al , Adel Ghada , Badawy Ahmed A. , Kasem Samaa A. , Elmawgoud Ashraf Abd , Badawy Yasmin A. 
Published: December 2018

Abstract
Purpose: The previous reports tried to reduce shivering and improve neuraxial anesthesia characteristics by the systemic use of different drugs. This study was directed to evaluate the effect of pregabalin premedication on both shivering and epidural characteristics following single shot loading.
Patients and Methods: Eighty female patients, ASA grade I and II, scheduled for gynecological surgeries under epidural anesthesia were studied. The patients were divided into two groups: Pregabalin (P) group and Control (C) group in which the patients received 150 mg of pregabalin and placebo capsules respectively sixty minutes prior to surgery. Following epidural loading, the onset and degree of shivering were compared between the two groups. Also, the epidural onset, level and duration were compared. The perioperative hemodynamics, sedation scores, meperidine consumption and side effects were followed up and registered.
Results: The onset of shivering was significantly prolonged and the degree of shivering was less in pregabalin group compared to Control group. The duration of epidural shot was shorter in the control group in relation to the pregabalin treated patients. Regarding both onset and level of block, no significant changes were detected. The patients were more sedated with less meperidine consumption in the pregabalin group. The two groups were similar as regards the perioperative hemodynamics and occurrence of side effect.
Conclusion: The premedication with pregabalin reduced onset and degree of shivering and prolonged the duration of single shot epidural block.
McCune-Albright Syndrome with Exophthalmos: A Case Report
Authors: Zhao Jinrong , Yu Jinguo 
Published: December 2018

Abstract
Background: McCune-Albright syndrome (MAS) is a rare disease defined by the triad of polyostotic fibrous dysplasia of bone, skin spots, and precocious puberty. No available treatment is effective in changing the course of fibrous dysplasia of bone, but symptomatic patients require the rapeutic support to reduce bone pain and prevent fractures and deformities.we reported 1 case of McCune-Albright syndrome with exophthalmos in clinical practice.
Case presentation:A 35-year-old female was admitted to our hospital who complained about “skin pigmentation for 35 years, vaginal bleeding for 30 years and progressive skeletal deformity for 28 years and exophthalmos for 2 years. And after the examination, she was been diagnosed with“McCune-Albright syndrome with exophthalmos”.We highlighted the pathogenesis and development of the disease in this rare condition.

Conclusion: McCune-Albright syndrome with exophthalmos due to multiple fibrous dysplasia is rare but can be seen in clinical practice.