bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of farrowing duration and parity on preovulatory follicular size and oxytocin release of sows at subsequent oestrus
Authors: Yun J , Björkman S , Oliviero C , Soede N , Peltoniemi O 
Published: March 2018

ContentsThis study examined the extent to which prolonged farrowing and parity are associated with plasma oxytocin concentrations and follicular development of oestrous sows during subsequent insemination. A total of 30 sows were allocated to two groups based on farrowing duration: (i) SHORT (n = 14): 159 ± 29 min, (ii) LONG (n = 16): 533 ± 190 min. The sows were also divided into two parity classes: (i) YOUNG (n = 14): parity 2.5 ± 0.8, (ii) OLD (n = 16): parity 6.4 ± 2.3. After weaning, the ovaries were examined daily with transrectal ultrasound. On the second day of oestrus, blood samples were collected for oxytocin (OT) assay at −15, −10, −5, 0, +1, +2, +3, +4, +6, +8, +10, +15, +20, +25, +30, +40, +50 and +60 min with a boar contact between 0 and +10 min. Boar presence stimulated an increase in OT concentrations (p < .05). During boar presence, OT in the LONG group was higher than in the SHORT group (p < .01). The sows in the OLD group had a longer farrowing duration than in the YOUNG group (p < .05). OT levels and diameters of follicles were more relevant for parity than was the duration of farrowing. We therefore conclude that the OT levels and follicular development of oestrous sows are associated due to parity but difficult to be predicted from the duration of previous farrowing.
Anti‐Muellerian hormone concentration in bitches with histopathologically diagnosed ovarian tumours and cysts
Authors: Walter B , Coelfen A , Jäger K , Reese S , Meyer‐Lindenberg A , Aupperle‐Lellbach H 
Published: March 2018

ContentsIncreased concentrations of Anti‐Muellerian hormone (AMH) can indicate a granulosa cell tumour as shown in women, mares and cows. To investigate AMH to differentiate canine granulosa cell tumour from other ovarian pathologies, we evaluated the ovaries of 63 bitches. Blood serum samples were collected before surgery for AMH analysis. Ovaries were submitted for histopathological examination. Fourteen bitches showed normal ovaries. These bitches had AMH values between 0.12 and 0.99 ng/ml. In 20 bitches ovarian cysts i.e., follicular cysts (n = 8), corpora lutea cysts (n = 7), subsurface cysts (n = 5) were diagnosed. These dogs had AMH values of 0.11–2.09 ng/ml. Bitches with small luteinized follicular cysts had slightly higher AMH values than those without ovarian alteration. In 29 cases ovarian neoplasms i.e., granulosa cell tumour (n = 9), epithelial tumours (n = 16), dysgerminomas (n = 3) and one sarcoma were identified. Anti‐Muellerian hormone values of bitches with an ovarian neoplasm except granulosa cell tumour ranged from 0.18 to 1.18 ng/ml. The AMH values of bitches with granulosa cell tumour ranged from 1.12 to ≤23 ng/ml and were significantly higher (p < .05) than in all of the other bitches. The cut‐off of 0.99 ng/ml gave a sensitivity of 100% and a specificity of 94.44% to diagnose granulosa cell tumour. In conclusion, markedly elevated AMH concentrations in bitches are indicative for a granulosa cell tumour. However, negative testing does not rule out the existence of small one. Differentiation of GCT from luteinized follicular cysts may especially be difficult.
Changes in plasma concentrations of S100A7 and S100A8 in dairy cows during pregnancy
Authors: Elgawish RA , Ogata Y , Hidaka T , Nii T , Yoshimura Y , Isobe N 
Published: March 2018

ContentsThis study was carried out to examine the changes in plasma concentrations of the Ca‐binding antimicrobial proteins S100A7 and S100A8 during pregnancy in dairy cows. Holstein Friesian cows (n = 19) were inseminated with Holstein Friesian semen. Blood was collected at days 30, 60, 90, 120, 150, 180, 210, 240 and 270 after insemination. Plasma was used for measuring the concentrations of S100A7 and S100A8. Both S100A7 and S100A8 concentrations showed similar patterns during gestation; they increased during the midgestation, between days 90 and 180, and then declined before calving. The findings indicated that plasma concentrations of S100A7 and S100A8 did not change significantly during pregnancy in cows. Further studies are required to determine the roles of S100A7 and S100A8 in physiological function during pregnancy in dairy cows.
Irradiation of semen doses with LED‐based red light in a photo chamber does not improve in vitro quality of thermically stressed boar spermatozoa
Authors: Luther A , Le Thi X , Schäfer J , Schulze M , Waberski D 
Published: March 2018

ContentsRecent reports indicate that stimulation of liquid‐stored boar semen with red LED‐based light improves sperm quality and reproductive performance in sow herds. So far, in vitro data after LED stimulation of whole semen doses are lacking. In this study, the effect of LED light exposure on the in vitro quality of boar spermatozoa after storage and thermic incubation was examined. Boar semen doses were stored at 17°C (n = 10) or 5°C (n = 6) in Beltsville Thawing Solution extender and then exposed to red LED light using a commercial photo chamber. During a subsequent long‐term incubation at 38°C, neither sperm kinematic parameters nor mitochondria function or membrane integrity differed between control and treated samples (p > .05). It is concluded that stimulation of semen doses in the LED‐photo chamber does not improve quality of thermically stressed boar sperm in vitro. Other than the sperm traits tested here might be involved in the previously reported improvement of in vivo fertility.
Differential promoter methylation of DAZL gene in bulls with varying seminal parameters
Authors: Sarova N , Ahlawat S , Grewal A , Sharma R , Arora R 
Published: March 2018

ContentsIn India, cross‐breeding of indigenous cattle with exotic cattle such as Holstein Friesian and Jersey has been going on since last four decades to improve milk production. Although it has led to increased milk yield, the subfertility in male cross‐bred progeny has remained a significant problem. Epigenetic modifications (DNA methylation, histone modifications and chromatin remodelling) are regarded as key players influencing gene expression. DAZL gene plays an important role in germline development and gametogenesis. The methylation and mRNA expression level of this gene have been significantly negatively correlated in the testes of cattle–yak hybrids and their parents. This study analysed the methylation profile of DAZL gene promoter in bull spermatozoa in an attempt to speculate its role in cross‐bred cattle subfertility. Semen samples from Sahiwal, Holstein Friesian and Frieswal bulls (Sahiwal X Holstein Friesian) with varying semen motility parameters were collected, and DNA was isolated. Methylation‐specific primers were used to amplify part of promoter and exon 1 of DAZL gene using bisulphite‐converted DNA. The amplified products were sequenced after cloning in pTZ57R/T vector. Sequence analysis revealed significantly higher DNA methylation of DAZL gene in Frieswal bulls with poor motility (28.26%) as compared to medium (15.21%) and high motility phenotype (6.52%). In pure‐bred counterparts, Sahiwal and Holstein Friesian, epigenetic marks were more in the former (15.21%) than the latter (4.34%), but in both cases, the values were lower as compared to the poor motility Frieswal bulls. This suggests that differential hypermethylation of the CpG islands could possibly influence reproductive parameters in bovines.
Geochemical Constraints on the Origin of Banded Iron Formation‐Hosted Iron Ore from the Archaean Ntem Complex (Congo Craton) in the Meyomessi Area, Southern Cameroon
Authors: Ganno Sylvestre , Tsozué Désiré , Kouankap Nono Gus Djibril , Tchouatcha Milan Stafford , Ngnotué Timoléon , Gamgne Takam Ruth , Nzenti Jean Paul 
Published: March 2018

AbstractBanded iron formations (BIFs) are the most significant source of iron in the world. In this study, we report petrographic and geochemical data of the BIF from the Meyomessi area in the Ntem Complex, southern Cameroon, and discuss their genesis and the iron enrichment process. Field investigations and petrography have revealed that the studied BIF samples are hard; compact; weakly weathered; and composed of magnetite, subordinate quartz, and geothite. The geochemical composition of the whole rock reveals that iron and silica represent more than 98 wt% of the average composition, whereas Al2O3, TiO2, and high‐field strength elements (HFSE) contents are very low, similar to detritus‐free marine chemical precipitates. The total iron (TFe) contents range from 48.71 to 65.32 wt % (average of 53.29 wt %) and, together with the low concentrations of deleterious elements (0.19 wt % P on average), are consistent with medium‐grade iron ores by global standards. This interpretation is confirmed by the SiO2/Fe2O3total versus (MgO + CaO + MnO)/Fe2O3total discrimination plot in which most of the Meyomessi BIF samples fall in the field of medium‐grade siliceous ore. Only one sample (MGT94) plots in the high‐grade magnetite–geothite ore domain. The high Fe/Ti (376.36), Fe/Al (99.90), and Si/Al (29.26) ratios of the sample are consistent with significant hydrothermal components. The rare earth elements (REE) contents of the studied BIF samples are very low (∑REE: 0.81–1.47 ppm), and the Post‐Archaean Australian Shale (PAAS)‐normalized patterns display weak positive Eu anomalies (Eu/Eu*: 1.15–1.33), suggesting a syngenetic low‐temperature hydrothermal solutions, similar to other BIF worldwide. However, the Meyomessi BIFs show high Fe contents when compared to the other BIFs. This indicates an epigenetic mineralization process affected the Meyomessi BIF. From the above results and based on the field and analytical data, we propose that the genetic model of iron ores at the Meyomessi area involves two stages of the enrichment process, hypogene enrichment of BIF protore by metamorphic and magmatic fluids followed by supergene alteration as indicated by the presence of goethite in the rocks.
Geriatric dentistry education and context in a selection of countries in 5 continents
Authors: Marchini Leonardo , Ettinger Ronald , Chen Xi , Kossioni Anastassia , Tan Haiping , Tada Sayaka , Ikebe Kazunori , Dosumu Elizabeth Bosede , Oginni Fadekemi O. , Akeredolu Patricia Adetokunbo , Butali Azeez , Donnelly Leeann , Brondani Mario , Fritzsch Bernd , Adeola Henry A. 
Published: March 2018

ABSTRACTPurpose/aimTo summarize and discuss how geriatric dentistry has been addressed in dental schools of different countries regarding to (1) teaching students at the predoctoral level; (2) advanced training, and (3) research.Method and materialsA convenience sample of faculty members from a selection of high, upper‐middle and lower‐middle income countries were recruited to complete the survey. The survey had 5 open‐ended main topics, and asked about (1) the size of their elderly population, (2) general information about dental education; (3) the number of dental schools teaching geriatric dentistry, and their teaching methods; (4) advanced training in geriatric dentistry; (5) scholarship/research in geriatric dentistry.Results and conclusion(1) There is great variation in the size of elderly population; (2) duration of training and content of dental education curriculum varies; (3) geriatric dentistry has not been established as a standalone course in dental schools in the majority of the countries, (4) most countries, with the exception of Japan, lack adequate number of dentists trained in geriatric dentistry as well as training programs, and (5) geriatric dentistry‐related research has increased in recent years in scope and content, although the majority of these papers are not in English.
The effect of 6 months or longer duration of chronic obstructive respiratory disease medication on the oral health parameters of adults
Authors: Raj Raashi , Manu Mohan K. , Prakash Peralam Y. , Singhal Deepak K. , Acharya Shashidhar 
Published: March 2018

ABSTRACTThe objectives of this study were to study the effect of COPD medication of 6 months or more duration on oral health parameters of adult patients. A cross‐sectional study was conducted to assess and compare the decayed, missing, and filled teeth (DMFT), oral hygiene index‐simplified (OHI‐S), periodontal disease index (PDI) scores, and presence of candida (colony‐forming units [CFU]) among adult patients aged 20–45 years who had a history of 6 months or longer duration usage of chronic respiratory disease medications, with controls. A total of 170 participants each were taken in both the groups. Oral health parameters like DMFT scores (p ≤ 0.002), OHI‐S (p ≤ 0.001), calculus scores (p ≤ 0.001), plaque scores (p ≤ 0.001), and CFU/ml of candida species (p ≤ 0.001) were higher among cases than controls. DMFT scores and candida presence were significantly higher among those whose treatment duration was greater than 5 years as compared to those with lesser duration. Gingival‐periodontal component scores of PDI were lower among cases than controls (p ≤ 0.001). Our findings suggest the need for regular oral health maintenance for those under COPD treatment and for greater research into the possible protective role of inhaled corticosteroids in limiting periodontal disease among patients.
Brown tumor of the jaws as a manifestation of tertiary hyperparathyroidism: A literature review and case report
Authors: dos Santos Bethina , Koth Valesca Sander , Figueiredo Maria Antonia , Salum Fernanda Gonçalves , Cherubini Karen 
Published: March 2018

ABSTRACTBrown tumor of the jaws is a manifestation of hyperparathyroidism consisting of osteolytic lesions that show proliferation of multinucleated giant cells in the maxilla and/or mandible. Differential diagnosis of these lesions from local central giant‐cell granuloma is mandatory for the correct treatment of the patient. Radiographic and histopathological exams of the jaw lesion are not sufficient to determine the diagnosis, which requires laboratory tests including serum levels of calcium, alkaline phosphatase, parathyroid hormone (PTH) and phosphate, and radiographic examination of other bones as well, such as hand‐wrist, pelvis, and femur. We present here a brief literature review focusing on the clinical and radiographic features, diagnostic criteria and treatment of brown tumor and also report a case of the disease affecting the jaw.
Fluvial products and processes before the evolution of land plants: Evidence from the lower Cambrian Series Rouge, English Channel region
Authors: Went David J. , McMahon William J. 
Published: March 2018

AbstractFluvial strata deposited before the advent of land plants are commonly sheet‐like in geometry, lacking in channel forms. Although some pre‐vegetation strata contrast strongly with fluvial strata from later eras, the characterization of pre‐Devonian fluvial drainage systems remains incomplete. Field studies of the fluvial facies and architecture of the Series Rouge are presented to identify the products and processes of fluvial deposition occurring at high latitudes in the early Cambrian. Three different depositional styles or facies associations are recognized. Facies Association 1 is the most abundant (67%) comprising repetitively stacked sheets of trough cross‐stratified sandstone interpreted to represent the preferential preservation of the deepest parts of low sinuosity, braided river channels, 4 to 6 m deep. Facies Association 2 is also common (30%) and displays more complex facies sequences that include stacked sheets of trough cross‐strata, sets of large‐scale tabular cross‐strata, planar strata and subordinate mudstone. These facies are interpreted to reflect deposition in braided rivers with deeper channels, 6 to 8 m deep. These channels were more sinuous and subject to steady lateral migration which resulted in preservation of both deep and shallow parts of the river. Facies Association 3 is uncommon (3%) comprising interbedded sequences of cross‐stratified sandstone and mudstone interpreted to reflect deposition on a muddy coastal plain in a mixture of braided and meandering channels, 1 to 3 m deep. The fluvial strata of the Series Rouge indicate that these pre‐vegetation drainage systems were predominantly braided fluvial in origin. However, the style of braided fluvial deposition varied according to discharge and valley slope, the braided rivers becoming more migratory with decreasing slope. Meandering channel deposition was locally evident but was restricted to channels of low discharge crossing low gradient muddy coastal plains.
Crestline bifurcation and dynamics in fluvially‐dominated, tidally‐influenced flow
Authors: Hendershot Megan L. , Venditti Jeremy G. , Church Michael , Bradley Ryan , Kostaschuk Ray A. , Allison Mead A. 
Published: March 2018

AbstractCurrent understanding of dune dynamics in rivers and estuaries in response to varying flows remains incomplete, particularly with respect to pattern evolution. This study presents observations of dune crestline change during the gradually varied flow caused by the influence of a diurnal tide on the fluvially‐dominated Fraser Estuary, British Columbia, Canada. Observations consist of a 1·0 km long and 0·5 km wide patch of a dune field mapped repeatedly during a falling and rising spring tide, on the rising limb of annual hydrograph immediately prior to peak freshet. The fundamental relations between dune geometry, translation rate, sediment flux and the birth, death and piracy of dune crestlines are explored. The data show that the bedform field consists of primary, channel‐spanning dunes with a series of interconnected secondary crestlines. The primary crestlines are two‐dimensional and experience little change over the tide cycle. The secondary crestlines impart a three‐dimensionality to the bedform field that is dynamic with the flow. There is a predominance of dune crestline bifurcation ‘deaths’ (disappearances) over ‘births’ (appearances) as flow velocity in the channel increases, suggesting that the crestline configuration is moving towards a more two‐dimensional configuration. As the flow wanes, bifurcation births outweigh deaths, suggesting that the dune field becomes more complex and three‐dimensional. The results suggest that the primary response to variable flow may be a simplification of the dune field towards a two‐dimensional configuration as flow increases and added complexity towards a more three‐dimensional configuration as the dune flow wanes.
CD38 protein deficiency induces autoimmune characteristics and its activation enhances IL‐10 production by regulatory B cells
Authors: Domínguez‐Pantoja M. , López‐Herrera G. , Romero‐Ramírez H. , Santos‐Argumedo L. , Chávez‐Rueda A. K. , Hernández‐Cueto Á. , Flores‐Muñoz M. , Rodríguez‐Alba J. C. 
Published: March 2018

AbstractCD38 is a transmembrane protein expressed in B lymphocytes, and is able to induce responses as proliferation, differentiation or apoptosis. Several reports propose that CD38 deficiency accelerates autoimmune processes in murine models of autoimmune diabetes, lymphoproliferation and rheumatoid arthritis. Other reports have shown elevated CD38 expression in B and T cells from patients with autoimmunity; however, the role of CD38 is still unclear in the development of autoimmunity. Recently, it has been characterized as CD1dhi CD5+ regulatory B cell subpopulation able to produce IL‐10, and the loss of these cells exacerbates the autoimmunity in murine models. Here, we report that CD38−/− mice exhibited elevated titres of ANAS, anti‐dsDNA autoantibodies from 12 months of age and were higher by 16 months of age and mice presented kidney damage. Interestingly, there is a reduction in the survival of CD38−/− mice compared to the WT. Furthermore, CD38 is highly expressed by CD1dhigh CD5+ regulatory B cells, and the agonistic anti‐CD38 stimulus plus LPS was able to increase the percentage of this cell subset and its ability to induce IL‐10 production. Together, these results suggest that CD38 could play a role in the control of autoimmune diseases through their expression on regulatory B cells.
Suicidality Disclosed Online: Using a Simulated Facebook Task to Identify Predictors of Support Giving to Friends at Risk of Self‐harm
Authors: Corbitt‐Hall Darcy J. , Gauthier Jami M. , Troop‐Gordon Wendy 
Published: March 2018

Although peer support in response to online disclosures of suicidality may be imperative for suicide prevention efforts, little is known as to how often support is provided or what predicts giving support. This study addresses this issue by investigating the odds of providing peer support in response to simulated online disclosures of suicidality. While interacting with a simulated Facebook newsfeed, participants (N = 690, Mage = 20.24, 527 female) were given the opportunity to leave comments on two posts disclosing low, moderate, or severe risk for suicide. Participants also completed questionnaires on their symptoms of depression and anxiety, experience with a loved one's suicidality, and Facebook use strategies. Only 33.6% of participants left a positive, supportive comment on at least one of the two suicide posts. Content severity, experience with a loved one's suicide attempts, and use of Facebook to meet people were predictive of providing positive comments. These findings suggest that young adults vary in their propensity to provide support after encountering a suicide disclosure online and that giving support is driven by a combination of contextual and intrapersonal factors.
Resistance band training or general exercise in multidisciplinary rehabilitation of low back pain? A randomized trial
Authors: Iversen V. M. , Vasseljen O. , Mork P. J. , Gismervik S. , Bertheussen G. F. , Salvesen Ø. , Fimland M. S. 
Published: March 2018

Multidisciplinary biopsychosocial rehabilitation has been recommended for chronic low back pain (LBP), including physical exercise. However, which exercise modality that is most advantageous in multidisciplinary biopsychosocial rehabilitation is unclear. In this study, we investigated whether multidisciplinary biopsychosocial rehabilitation could be more effective in reducing pain‐related disability when general physical exercise was replaced by strength training in the form of progressive resistance training using elastic resistance bands. In this single‐blinded (researchers), randomized controlled trial, 99 consenting adults with moderate‐to‐severe non‐specific LBP were randomized to three weeks of multidisciplinary biopsychosocial rehabilitation with either general physical exercise or progressive resistance band training and were then instructed to continue with their respective home‐based programs for nine additional weeks, in which three booster sessions were offered. The primary outcome was between‐group difference in change on the Oswestry Disability Index (ODI) at 12 weeks. Due to early dropouts, data from 74 participants (mean age: 45 years, 57% women, mean ODI: 30.4) were obtained at baseline, 61 participants were followed‐up at 3 weeks, and 46 at 12 weeks. There was no difference in the change in ODI score between groups at 12 weeks (mean difference 1.9, 95% CI: −3.6, 7.4, P = .49). Likewise, the change in secondary outcomes did not differ between groups, except for the patient‐specific functional scale (0‐10), which favored general physical exercise (mean difference 1.4, 95% CI: 0.1, 2.7, P = .033). In conclusion, this study does not support that progressive resistance band training compared to general physical exercise improve outcomes in multidisciplinary biopsychosocial rehabilitation for patients with non‐specific LBP.