bluuebunny/crossref_metadata_2025_split huggingface dataset:
DETERMINATION OF CLOMIPRAMINE HYDROCHLORIDE FROM ITS COMMERCIAL DRUG FORM BY VOLTAMMETRY
Authors: UGURLU Elif , YAĞMUR Sultan , YILMAZ Selehattin 
Published: January 2019

In this study, electroanalytical technique was developed for the quantitative analysis of clomipramine hydrochloride from its commercial tablet dosage forms based on its oxidation behavior. The electrochemical determination of clomipramine hydrochloride was easily carried out on glassy carbon electrode (GCE) by two voltammetric techniques. The electrochemical measurements were carried out on GCE surface in different buffer solutions in the pH range from 2.00 to 12.00 by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The efect of pH on the anodic peak current and peak potential was investigated. Phosphate buffer (pH 6.50) was selected for analytical purposes. The diffusion-controlled nature of the peak was obtained. A linear calibration plot for DPV analysis was constructed in the clozapine concentration range from 5x10-6 mol L-1 to 3x10-5 mol L-1. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 2.8x10-7 mol L-1 and 8.4x10-7 mol L-1 respectively. Validation of applied voltammetric techniques was applied.
BIOMONITORING OF HEAVY METALS DEPOSITION WITH PSEUDEVERNIA FURFURACEA (L.) ZOPF IN ÇORUM CITY, TURKEY
Authors: YILDIZ Atila , VARDAR Çiğdem , AKSOY Ahmet , ÜNAL Ediz 
Published: January 2019

Heavy metal air pollution is an important environmental problem. One of the methods used to monitor pollution in air is the method of transplanting lichen samples by the "bag technique". In this study, Pseudevernia furfuracea was used as a bioindicator to determine the heavy metal level in the air of Çorum and to generate an air pollution map of the city. The lichen samples were collected from the Yapraklı Mountains in Çankırı in 2002 and transplanted to 8 different stations in Çorum. Lichen samples were retrieved at two different periods in three month intervals. Inductively Coupled Plasma (ICP) spectrometry (Varian Liberty ICP-OES Sequential) was used to identify the heavy metals, such as copper (Cu), cadmium (Cd), manganese (Mn), nickel (Ni), lead (Pb) and zinc (Zn) in the lichen samples. The chlorophyll a and b contents were determined by using the modified DMSO (dimethyl sulfoxide) method. With these values chlorophyll a+b, a/b and b/a were also calculated. According to the results of the heavy metal analysis by the use of P. furfuracea, air pollution levels in Çorum was detected. The reasons of pollution can be stated as heavy traffic, industrial activities and heating processes in the city. P. furfuracea can be used as a bioindicator for pollution studies.
Klasifikasi Malicious Websites Menggunakan Algoritma K-NN Berdasarkan Application Layers dan Network Characteristics
Authors: Sandag Green Arther , Leopold Jonathan , Ong Vinky Fransiscus 
Published: January 2019

Dalam kehidupan di era teknologi sekarang ini semua aktivitas manusia telah dipengaruhi oleh internet. Berbagi informasi, komunikasi, sosialisasi, berbelanja, berbisnis, pendidikan dan banyak hal lainnya yang dapat dilakukan menggunakan internet. Seiring dengan berkembangnya internet berbagai macam ancaman keamanan menjadi lebih beragam. Virus adalah musuh nomor satu di internet. Virus memanfaatkan berbagai metode untuk dapat menghindari anti-virus, salah satunya adalah Malware. Malware adalah salah satu kode berbahaya yang dapat mengubah, merusak dan mencuri data pribadi yang dapat merugikan individual ataupun kelompok. Penelitian ini akan memprediksi malicious website berdasarkan application layer dan network characteristics menggunakan metode K-Nearest Neighbor. Penelitian ini menggunakan metode data cleaning dan data reduction untuk data preprocessing, dan feature selection untuk pemilihan attribut yang paling berpengaruh pada malicious website. Untuk memprediksi malicious website penulis menggunakan algoritma K-NN dengan hasil 2,42% precision lebih tinggi dibandingkan dengan penelitian sebelumnya yang menggunakan algoritma Naïve Bayes. Keywords : Klasifikasi, Network Characteristics, Malicious Websites, Application Layers, K-NN, Naïve Bayes
Bioinformatics Tools for Data Processing and Prediction of Protein Function
Authors: Sandag Green Arther , Taju Semmy Wellem 
Published: January 2019

Bioinformatika semakin populer karena kemampuannya untuk menganalisis dan memproses data biologis dengan cepat dan efektif. Bagian penting dari bioinformatika adalah untuk mengidentifikasi fungsi dan karakteristik protein dengan membangun metode prediksi menggunakan algoritma pembelajaran mesin. Ini termasuk bagaimana pembelajaran mesin dapat digunakan untuk menganalisis dan mengklasifikasikan fungsi protein yang cocok untuk digunakan sebagai deteksi penyakit, merancang perawatan medis yang tepat untuk pasien, dan mengembangkan obat untuk beberapa penyakit. Permintaan untuk pembuatan predictive tools dalam menentukan model protein-ligand dan fungsi protein meningkat untuk mempromosikan penelitian biologi dalam lingkungan desain obat yang inovatif. Namun, dibutuhkan banyak waktu dan upaya untuk mengembangkan alat prediksi yang dapat diterapkan pada protein. Dalam penelitian ini kami mengembangkan tools bioinformatika yang dapat secara otomatis mengembalikan data protein dalam bentuk komposisi asam amino (AAC), komposisi pasangan dipeptida (DPC), dan matriks penentuan spesifikasi posisi (PSSM). Data protein, telah kita ambil dari database uniprot yang berisi file fasta. Penelitian ini, kami membuat alat untuk memfasilitasi ilmuwan dalam memproses atau menganalisis data protein dan juga dapat memprediksi fungsi protein menggunakan algoritma pembelajaran mesin seperti Neural Network dan Random Forest. Kata Kunci—Bionformatika, AAC, DPC, PSSM
In Vitro Sitotoksisite Testleri
Authors: TOKUR Orhan , AKSOY Abdurrahman 
Published: January 2019

Kimyasal ve biyolojik maddeler ya da fiziksel
etkenler, hücreleri değişik derecelerde etkileyerek sitotoksisiteye yol
açabilirler. Bir maddenin biyolojik davranışının anlaşılabilmesi için hücreler
üzerindeki toksik ya da non-toksik etkisinin belirlenmesi gereklidir. İn vitro
sitotoksisite testleri, ilaç niteliği taşıyan veya toksik profili araştırılan
maddelerin değerlendirilmesi amacıyla hücre kültüründe gerçekleştirilen ölçüm
metodlarıdır. Bu testlerle çok sayıda maddenin kısa sürede analiz edilmesi mümkün
olmakta ve yapılacak hayvan denemeleri için temel veriler elde edilebilmektedir.
Farklı mekanizmalara ve hassasiyetlere sahip çok sayıda sitotoksisite testi
bulunmakla birlikte bu derlemede, araştırmacılar tarafından sıkça tercih edilen
tetrazolyum testleri (MTT, MTS, XTT, WST), LDH testi, alamalar mavisi testi ve
biyolüminesans testleri ele alınmıştır.
Oklu Kirpilerde Böbreklerin Bilgisayarlı Tomografi ile İncelenmesi
Authors: ATALAR Ömer , KOÇ Mustafa , İLGÜN Ramazan , YILMAZ Bestami 
Published: January 2019

Yapılan literatür taramalarında; oklu kirpilerin
böbrekleri üzerinde, iki ve üç boyutlu görüntüleme ile yapılan bir araştırma
bulunmadığı tespit edilmiştir. Bu araştırma, oklu kirpilerde ilk kez;
bilgisayarlı tomografik görüntüler kullanılarak, böbreklerin detaylı
anatomisini elde etmek için planlanmıştır. Çalışma, 5 erkek ve 5 dişi olmak
üzere toplam 10 erişkin oklu kirpi üzerinde yapılmıştır. Multidetektör bilgisayarlı
tomografi (MDCT) cihazından sağlanan görüntüler, üç boyutlu (3D) modelleme
yazılımı (VITAL, Vitrea 2, HP XW6400 Workstation, ABD) ile, böbreklerin 3D
modelinin oluşturulması için kullanılmıştır. Böbreklerin en, boy ve kalınlıkları
ile merkezlerinin columnavertebralis’e olan uzaklıkları ölçülmüştür.Ölçüm
değerleri, tablo halinde sunulmuştur. Veriler istatistiksel olarak analiz
edilmiştir. Bir erkek ve bir dişi iki materyal hariç, bütün hayvanlarda, sağ
böbrek ölçümleri sol böbrekten daha yüksek olarak saptanmıştır. İstatistiksel analiz sonuçlarına göre;
hacim, genişlik ve kalınlık değerlerinde, anlamlı bir istatistiksel fark bulunduğu
görülmüştür. Araştırmanın; oklu kirpilerde ilk kez yapılmış olması sebebiyle, hem
anatomi alanındaki incelemelere, hem de ileride yapılacak benzer alanlardaki
çalışmalara kaynak teşkil edebilmesi bakımından anlamlı olduğu düşünülmektedir.
ADESÃO E ADERÊNCIA AO EXERCÍCIO: Um Estudo Bibliográfico
Authors: Telles Thabata Castelo Branco , Araruna Lara Cavalcante , Almeida Mayara Silva , Melo Anna Karynne 
Published: January 2019

Este trabalho tem como objetivo investigar os processos de adesão e aderência ao exercício na idade adulta, a partir de pesquisa bibliográfica. Foram selecionados textos publicados entre 2003 e 2013, nas bases de dados: LILACS, SciELO e BIREME, com as palavras-chave: exercício, adesão e aderência. Dentre os resultados, a relação entre prevenção de doenças e prática de exercício foi predominante, e a musculação, a dança e a corrida de rua aparecem como os principais exercícios estudados. Foi constatado também que a constância e a regularidade na prática de exercícios ocorrem por motivos associados à busca da saúde física e mental. A socialização foi um aspecto que apareceu muito como incentivador para a aderência, já a falta de tempo predominou como um fator de dificuldade no que concerne tanto à adesão quanto à aderência. Concluímos com a necessidade de que sejam realizados mais estudos desta natureza, principalmente no Brasil, para que essa temática seja mais explorada e desenvolvida, aumentando assim a compreensão de como a psicologia do esporte e do exercício pode auxiliar nos processos de adesão e aderência ao exercício. Palavras-chave: exercício, adesão e aderência.
O que faz uma mulher no Mixed Martial arts? Reflexões de um relato de pesquisa.
Authors: Camilo Juliana A de Oliveira , Pereira Adriana Bernardes 
Published: January 2019

O presente trabalho se propõe a uma reflexão crítica sobre a presença de uma mulher como partícipe de uma equipe técnica de alto rendimento em um contexto do Mixed Martial Arts (MMA). São feitas considerações a partir dos conceitos de pós-modernidade (Lyotard, 1989); sociedade do espetáculo (Debord,1992) e as concepções feministas de gênero da sua segunda onda (Scott, 2005). São apresentados, também, os relatos de experiência vividos por uma pesquisadora, mulher, e as tensões envolvidas quando ela se faz presente na rotina de treinamentos e contexto social de um lutador de Mixed Martial Arts (MMA) em momentos prévios a uma luta de grande visibilidade nacional (UFC).Palavras Chaves: Artes Marciais Mistas, Psicologia do esporte, Gênero, Lutas.
Estados de humor, percepção subjetiva do estresse e recuperação e condicionamento físico da Seleção Brasileira Militar de Futebol no início da temporada de 2015
Authors: Xavier Ivo Soares , Kasai Mario Yoshiro , Maia Junior José Mauro Malheiro , Mainenti Miriam Raquel Meira , Neves Angela Nogueira 
Published: January 2019

O constante desempenho esportivo de excelência é a realidade dos atletas, sendo importante o acompanhamento dos estados de humor e percepção de estresse e recuperação. O objetivo do presente estudo foi traçar o perfil dos estados de humor, da percepção subjetiva do estresse e recuperação da fadiga, correlacionando-os também com uma medida de condicionamento físico, o volume máximo de oxigênio (VO2max), em atletas da Seleção Brasileira Militar de Futebol. Fizeram parte do estudo 21 jogadores, entre 19 e 40 anos. Foram usadas na avaliação as versões Brasileiras do Recovery Stress Questionnaire for Athletes e da Brunel Mood Scale, além do teste de esforço cardiopulmonar em cicloergômetro com protocolo de rampa adaptado (modulando apenas a velocidade). Todos os testes foram realizados no software SPSS15. Descritivamente, podemos verificar que os fatores de recuperação tem uma tendência a maior escore que os fatores de estresse, tanto aqueles específicos do esporte quanto os gerais. Os escores de humor negativos apresentaram média e dispersão menor que o escore de vigor. Houve associação negativa entre o VO2max e o fator de Estresse Social e o fator fadiga. Os fatores Conflito, Bem Estar Geral e Descanso Atrapalhado variaram em função da posição de campo. A comissão técnica pode monitorar e orientar seus atletas a manejar o cansaço e desgaste de uma forma geral, não apenas no contexto esportivo, uma vez que se mostram importantes na associação com condicionamento físico e no posicionamento em campo.
An integrated study of the electrical parameters of the samples of magnetite ores in relation to their genesis and mineral composition (on the example of the Goroblagodatskoe skarn-magnetite deposit)
Authors: Bakhterev V. V. 
Published: January 2019

The temperature dependences of electrical resistance (at DC and AC voltage at 1 kHz frequency) of the samples of the magnetite ore and magnetite from the contact of the syenite-porphyry with the volcanic-sedimentary rocks from the Goroblagodatskoye iron-ore deposit in the temperature range 20—800 °C have been studied. The frequency dependences of the active electrical resistance and dielectric losses in the range 0,01—100 kHz have been obtained at 20 °C. For the magnetite ore and magnetite from the syenite-porphyry contact with volcanogenic sedimentary rocks in the studied temperature and frequency ranges, the relationship between electrical resistance (lgR) and dielectric losses (lgtgδ) has been revealed. The character of the relations is different, that allows to separate uniquely the magnetite ore and magnetite. The parameters of high-temperature conductivity (activation energy Eoand electrical resistance coefficient lgRo)nave been obtained. The parameters of the studied samples of pyroxene-orthoclase-magnetite, garnet-magnetite, epidote-chlorite-magnetite ores form a straight line, as if forming its different parts. The correlation between the parameters of E0and lgRo, samples of these ores has the following form: lgRo, — 2,2—6,6 Eo. The parameters of magnetite samples from the contact of syenite porphyry with volcanogenic-sedimentary rocks also form a straight line, as if forming its different parts, with the correlation form as following: lgRo— 2,1—6,6 E0. It has been found that with the increasing distance to the syenite intrusion, the electrical parameters of magnetite ore change: EQ increases, lgRo, decreases. For magnetite from the contact of the syenite-porphyry and volcanic-sedimentary rocks there is another picture — the further you are from the syenite-porphyries, the smaller E0is, and the bigger the lgRo, is. The T0temperatures, at which the electrical resistance at the constant voltage becomes equal to the active resistance at the alternating voltage for the samples of garnet-magnetite ore with the different magnetite content, P,%, have been revealed. The correlation between the T0 parameter and the magnetite content in the ore, P(Fe304, %) = 323,4 — 47,4 ln( T0), R2= = 0,93, has been established.
Research and reporting
Authors: Khan Mohammad Iqbal 
Published: January 2019

Research is indispensable for the growth and development of all disciplines, particularly medical sciences which fundamentally need continuous research and progressive innovation. Writing and reporting scientific discoveries is an important outcome of a researcher. Mostly, editors and reviewers appreciate manuscripts that are easy to read and to edit beside valuable scientific contents. Medical writings have significantly improved in past two decades resulting in increased number of medical journals and quality of reporting. Once research findings are ready to be reported, a researcher makes an educated choice, as to where to get it published. A high impact factor indicates that research findings published in journal are considered highly influential. With stirring zeal and drive, the “Journal of Shifa Tameer-e-Millat University” (JSTMU) is being launched and a dedicated team of editors, advisors and reviewers has been appointed to facilitate the researchers who wish to publish in JSTMU.
Physicians’ and Nurses’ perspectives on the importance of advance directives in tertiary care hospitals
Authors: Panjwani Nasreen , Gul Raisa , Ali Fauziya , Khan Robyna 
Published: January 2019

Objective: This study aimed to explore and identify the nurses’ and physicians’ views about Advance Directives and identified their perspectives on its importance, in the context of Pakistan.
Methodology: Using a purposive sample, six physicians and seven nurses from two tertiary care hospitals in Karachi participated in the study. Data was collected using semi structured interviews that were transcribed verbatim. The interviews were coded and categorized manually. Analysis of the data drew four categories: roles of physicians and nurses in the End of life care, challenges they faced while taking end of life care decisions; their perspectives about Advance Directives, and the scope of acceptability of Advance Directives in the context of a Pakistani society.
Results: This study revealed that patients’ families and physicians usually take decisions for patients’ End of Life care. Although majority of participants acknowledged the usefulness of Advance Directives, they explicated several issues that may be encountered in implementing it. The issues included non-disclosure of diagnosis to the patient in Pakistani culture, the tedious legalization process involved, and the potential problem of forged documents.
Conclusion: Participants recommended establishment of Palliative Care services before execution of Advance Directives. This study indicated viability of Advance Directives; however, a wider exploration would be required in terms of study population. Reforms to support this concept would be required in systems, structure, legal policy, and training of Health care professionals. Besides these transformations, promotion of public education about the advantages of Advance Directives could enhance their acceptability among the general population.
Awareness among medical students in Islamabad and Rawalpindi regarding use of anti-bacterial soaps: A cross-sectional study
Authors: Shaheen Abida , Javed Nismat , Azam Fahad , Ata Madiha , Zafar Anoosh 
Published: January 2019

Objective: The objective of this study was to determine the knowledge, practices and attitudes of undergraduate medical students about anti-bacterial soaps and hand sanitizers.
Methodology: This was a cross-sectional study conducted with the help of a self-designed, validated online and paperback questionnaire. The questions were based on knowledge, attitudes and practices of students regarding antibacterial soaps and hand sanitizers.
Results: A total of 474 students participated in the study. Majority of the students preferred medicated soaps (55.7%) and hand sanitizers (41.6%) for daily use and considered these products to be superior to regular non-medicated soaps and hand sanitizers. Television commercials (61.8%) were the most common source of information about these products. Medical students found it important to further increase the use of medicated soaps for better protection against disease causing microbes.
Conclusion: Majority of the study participants were conscious about hygiene and hand sanitization because of interaction with patients. Moreover, most of the students perceived medicated soaps and hand sanitizers to be effective for protection against disease causing microbes under the influence of media marketing campaigns.
Medical students assisted health checkup and focused health education – An integration of community and family medicine
Authors: Naseem Sajida , Ghazanfar Haider , Fatima Syeda Hanaa , Ghazanfar Ali 
Published: January 2019

Objective: The objective of the study was to integrate family medicine practice with the theme of school health service, nutrition and communication skills in the year 4 MBBS curriculum at Shifa College of Medicine, Islamabad.
Methodology: Health checkup of students aged 5-15 years, in a private school Mashal Model School, Nurpur Shahan, Islamabad was carried out by a family physician assisted by 100 medical students of Year 4, undergoing Community and Family Medicine clerkship at Shifa College of Medicine, Islamabad. School children were given health education in their identified health problem. Medical students’ views regarding the activity were recorded through focused group discussion.
Results: Each medical student got the opportunity to assist health checkup along with educating them on their health issue in an interactive group discussion for five minutes. Mean score of the impact of this activity on their career was found to be 7.55±1.04 while the impact of this activity in their role as a health provider was found to be 7.64±1.12. Different themes were generated from the focused group discussion.
Conclusion: Themes of school health service, nutrition and communication skills can be successfully integrated in the undergraduate teaching of community and family medicine. Medical students by assisting the generalist practice in the school environment can learn communication skills, thus moving towards social responsibility.
اهمية القياس والإفصاح المحاسبي عن رأس المال الفكري لتعظيم قيمة الشركة
Authors: الدوغجي علي حسين , سيد علي اسامة عبد المنعم 
Published: January 2019

ادركت اغلب الشركات الكبيرة وخاصة المعرفية منها على حقيقة مهمة هي ان رأس المال الفكري في الاقتصاد العالمي الجديد مورد جدي لها وهذا المورد الثمين يتفوق في اهميته على باقي موارد الشركة.
ان نظم الإفصاح التقليدية غير قادرة على تزويد متخذي القرارات بالمعلومات الاساسية اللازمة لإدارة العمليات القائمة على المعرفة والموارد غير الملموسة. ولكن قياس هذا المورد والافصاح عنه في القوائم المالية سيؤدي الى الحصول على مزايا تفيد كافة الاطراف نتيجة تأثيره المباشر في تعظيم قيمة الشركة.
وعليه يتعين على مهنة المحاسبة التفاعل في ظل التطور التكنولوجي واقتصاد المعرفة قياس هذا المورد والإفصاح عنه في القوائم المالية بهدف الاستمرار بتوفير العملاء والمستخدمين ذوي النوعية المتفوقة بكافة المعلومات التي تظهر القيمة الحقيقية للشركة والتي يحتاجونها في اتخاذ قراراتهم.
وقد تم التوصل الى عدة استنتاجات اهمها:

ان مفهوم رأس المال الفكري هو مفهوم دائم التجديد بسبب البيئة سريعة التغير المحيطة بجميع اجزاء الشركة لذلك فإنه لا يزال في مرحلة النمو والتطور وهو يعبر بصورة خاصة عن الاصول المعرفية (غير المادية).
تكون المحافظة على رأس المال الفكري بقيام ادارة الشركة بإستيعاب المعرفة المخزونة في عقول الموظفين وجعلهم ينقلونها الى الموظفين الجدد او تدريبهم على ذلك الشيء.
رأس المال الفكري يساعد على تقييم المخاطر والمساعدة على توليد القيمة الحقيقية للشركة وكذلك يمكن ان يكون هو المفتاح الحقيقي لتحقيق الازدهار المستقبلي للشركة.
تقديــر دالــة المخاطــرة المختلطة
Authors: عبود حسام نجم 
Published: January 2019

في هذا البحث تم اجراء المقارنة بين مقدرات الامكان الأعظم ومقدرات بيز بتوظيف أسلوب المحاكاة بطريقة مونت كارلو لكل من دالة المخاطرة المختلطة ودالة المعوليه وكل منهما بدلالة المعلمتين λ و P حيث ان λهي معلمة القياس و P احتمال عدم تأثر النظام بالضغوط البيئية وتم التوصل إلى أفضلية طريقة الامكان الأعظم على طريقة بيز لتقدير المعلمة P ودالة المخاطرة المختلطة وداله المعوليه في حين كانت طريقة بيز الأفضل لتقدير معلمة القياس λ.