bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microbiological evaluation of LOCATOR® Legacy attachments: A cross‐sectional clinical study
Authors: Nagy Ursina , Guédat Christophe , Giannopoulou Catherine , Schimmel Martin , Müller Frauke , Srinivasan Murali 
Published: July 2019

AbstractObjectiveThis retrospective cross‐sectional study aimed to evaluate quantitatively the oral microbiome in the tri‐lobe central cavity of Locator Legacy attachment and verify whether it harbors a different, potentially more pathogenic, bacterial spectrum than the adjacent edentulous ridge.Materials and MethodsEdentulous patients rehabilitated with implant overdentures using Locator Legacy attachments were recruited for this study. The clinical examination comprised probing depths, mobility, peri‐implant, and periodontal health along with intraoral swabs for microbiological evaluation, polymerase chain reaction (PCR) testing, and candida culture. The swabs were collected from the trilobed cavity of the attachment and the adjacent edentulous ridge. PCR was performed to detect six specific bacteria, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Tannerella forsythia, Treponema denticola, Prevotella intermedia, and Parvimonas micra. Statistical analyses were performed using McNemar's test and Wilcoxon's rank sum test with the significance set to p < .05.ResultsA total of 50 participants with a mean age of 71.5 ± 9.6 years participated in the study. No significant differences in the microbiome were found between samples from the ridge and the attachment. No significantly different numbers in the candida cultures were identified, and the presence of a removable prostheses did not demonstrate a significant association with the prevalence of candida.ConclusionsWithin the limits of this study and the investigated bacterial species, the trilobed cavity of the attachment does not seem to increase the bacterial load.
Utilizing the density of inventory samples to define a hybrid lattice for species distribution models: DISTRIB‐II for 135 eastern U.S. trees
Authors: Peters Matthew P. , Iverson Louis R. , Prasad Anantha M. , Matthews Stephen N. 
Published: July 2019

Abstract

Species distribution models (SDMs) provide useful information about potential presence or absence, and environmental conditions suitable for a species; and high‐resolution models across large extents are desirable. A primary feature of SDMs is the underlying spatial resolution, which can be chosen for many reasons, though we propose that a hybrid lattice, in which grid cell sizes vary with the density of forest inventory plots, provides benefits over uniform grids. We examine how the spatial grain size affected overall model performance for the Random Forest‐based SDM, DISTRIB, which was updated with recent forest inventories, climate, and soil data, and used a hybrid lattice derived from inventory densities.

Modeled habitat suitability was compared between a uniform grid of 10 × 10 and a hybrid lattice of 10 × 10 and 20 × 20 km grids to assess potential improvements. The resulting DISTRIB‐II models for 125 eastern U.S. tree species provide information on individual habitat suitability that can be mapped and statistically analyzed to understand current and potential changes.

Model performance metrics were comparable among the hybrid lattice and 10‐km grids; however, the hybrid lattice models generally had higher overall model reliability scores and were likely more representative of the inventory data.

Our efforts to update DISTRIB models with current information aims to produce a more representative depiction of recent conditions by accounting for the spatial density of forest inventory data and using the latest climate data. Additionally, we developed an approach that leverages a hybrid lattice to maximize the spatial information within the models and recommend that similar modeling efforts be used to evaluate the spatial density of response and predictor data and derive a modeling grid that best represents the environment.
Applying the resource dispersion hypothesis to a fission–fusion society: A case study of the African lion (Panthera leo)
Authors: Mbizah Moreangels M. , Valeix Marion , Macdonald David W. , Loveridge Andrew J. 
Published: July 2019

AbstractThe relationship between the spatiotemporal distribution of resources and patterns of sociality is widely discussed. While the resource dispersion hypothesis (RDH) was formulated to explain why animals sometimes live in groups from which they derive no obvious benefits, it has also been successfully applied to species that benefit from group living. Some empirical tests have supported the RDH, but others have not, so conclusions remain equivocal and further research is required to determine the extent to which RDH predictions hold in natural systems. Here, we test four predictions of the RDH in an African lion population in the context of their fission–fusion society. We analyzed data on group composition of GPS‐collared lions and patterns of prey availability. Our results supported the first and second predictions of the RDH: Home range size (a) was independent of group size and (b) increased with distance between encounters with prey herds. Nonetheless, the third and fourth RDH predictions were not supported: (c) The measure of resource heterogeneity and (d) resource patch richness measured through prey herd size and body size had no significant effect on lion group size. However, regarding the fourth prediction, we added an adaptation to account for dynamics of fission–fusion society and found that the frequency of pride fission increased as group size increased. Our data set restricted us from going on to explore the effect of fission–fusion dynamics on the relationship between group size and patch richness. However, this should be investigated in future studies as including fission–fusion dynamics provides a more nuanced, realistic appreciation of lion society. Our study emphasizes the importance of understanding the complexity of a species' behavioral ecology within the framework of resource dispersion. Whatever larger theoretical framework may emerge to explain lion society, incorporating fission–fusion dynamics should allow the RDH to be refined and improved.
Correlation between VOC fingerprinting and antimicrobial activity of several essential oils extracted by plant resins against A. tumefaciens and P. savastanoi
Authors: Caparrotta Stefania , Comparini Diego , Marone Elettra , Kimmenfield Rebecca , Luzzietti Laura , Taiti Cosimo , Mancuso Stefano 
Published: July 2019

AbstractThe present work aimed to assess the antimicrobial activity of twelve essential oils extracted from plant resins of trees that grow in several tropical and subtropical regions of the world. Eleven essential oils were extracted from resins of plant belonging to the Burseraceae family (the genera Boswellia, Commiphora, Canarium and Bursera); the remaining oil was extracted from a resinous plant belonging to the Fabaceae family (genus Hymenea). The extraction was carried out using a conventional distillation method. The volatile organic compounds (VOCs) of each essential oil were analyzed with PTR‐ToF‐MS (proton transfer reaction time‐of‐flight mass spectrometry) and the antimicrobial activity was evaluated against the phytopathogens Agrobacterium tumefaciens and Pseudomonas savastanoi pv. savastanoi. The essential oils obtained from Boswellia papyrifera, B. dalzielii, B. frereana and B. rivae were the most abundant in terms of signal intensity and VOC number in comparison with the other analyzed essential oils. Furthermore, B. neglecta shared a common volatile profile with the Canarium species, as was demonstrated previously in the literature. Greater bacterial growth inhibition of A. tumefaciens was detected with the essential oils extracted from plants belonging to Boswellia species while less action was observed against P. savastanoi. Finally, a positive correlation was found between terpenes and terpenoid compounds and bacterial growth inhibition, suggesting these essential oils as a new source of bioactive compounds for the prevention, protection and treatment of plant diseases.
Financial market imperfections and profitability: New evidence from a large panel of US SME firms
Authors: Apergis Nicholas 
Published: July 2019

AbstractThis paper investigates the impact of financial market imperfections on small and medium‐sized enterprise (SME) firms' profitability by using a unique panel data of US SME firms, spanning the period 1979–2017. The data set makes use of unique information on proxies of market imperfections pertaining to each firm in the sample. First, the findings document the statistical impact of those financial market imperfections on profitability. Moreover, the forecasting exercise illustrate the superiority of the model that explicitly includes those proxies.
Unwinding Entangled Degradation Mechanisms in Solid Oxide Electrolysis Cells Through Electrode Modifications and Impedance Analysis
Authors: Rao M. , Jensen S. H. , Sun X. , Hagen A. 
Published: July 2019

AbstractIn the renewable energy scenario, energy storage is of essence. In this context, power‐to‐liquid (PtL) and power‐to‐gas (PtG) concepts have attracted large attention, where the use of solid oxide electrolysis cells (SOECs) has a huge potential, due to their high conversion efficiencies. However, performance and durability of these cells still need to be improved for a large‐scale commercialization of the SOEC technology. It is often difficult to identify the various loss and degradation mechanisms limiting the cell performance and durability. This paper contributes to this scientific discussion, by providing a careful analysis of the degradation mechanisms occurring in three different cells during long‐term H2O and CO2 co‐electrolysis, at 1,200 mV. Electrochemical impedance spectroscopy (EIS) is measured before, during and after the electrolysis operation, and is utilized to address the individual electrode degradation mechanisms and the development of leaks through the electrolyte. Moreover, the leak rates under open circuit voltage (OCV) measurements were compared. In addition, microstructural analysis of the electrodes and electrolytes is related to the electrochemical findings to contribute to the discussion on the interdependency of the degradation mechanisms.
Impact of cavity chord shape on the free convection heat transfer rate in a triangular cavity
Authors: Rabani Mehran 
Published: July 2019

AbstractIn this study, the effect of different chord shapes of a triangular cavity has been investigated on the natural convection heat transfer characteristics inside the cavity using the commercial ANSYS‐FLUENT software. Heat transfer phenomena have been regarded as very significant due to the widespread application of natural convection heat transfer in different engineering fields. According to the performed studies, the chord with partitions can considerably enhance the natural convection heat transfer rate inside the cavity. Four different types of partitions including zigzag, two types of rectangular and sinusoidal were considered on the chord of the triangular cavity. The dimensionless parameters investigated in the results include Rayleigh number, Prandtl number, and Nusselt number. The results comprise the isotherm lines, streamlines, velocity lines, local and average Nusselt numbers analyzed with regard to the chord type and Rayleigh number variation. The results revealed that the temperature trend is almost the same for all configurations. Furthermore, the average Nusselt number value in zigzag and sinusoidal is higher in comparison with other cases due to the larger heat transfer area. Finally, by examining the streamlines, isotherm and velocity lines, average and local Nusselt numbers, it was founded that the cavities with zigzag and sinusoidal chord shape have the better performance in terms of heat transfer rate.
Heat transfer enhancement using hybrid nanofluids in spiral plate heat exchangers
Authors: Returi Madhuri Charulatha , Konijeti Ramakrishna , Dasore Abhishek 
Published: July 2019

AbstractA possible way to enhance the rate of heat transfer in the spiral plate heat exchanger (SPHE) is by employing hybrid nanofluids as its working medium. Hence, in the present work, effects of hybrid nanofluids on the thermal performance of SPHE has been investigated numerically. First, a countercurrent SPHE is designed and modeled. Later, simulation of SPHE has been carried out by employing conventional fluid , nanofluids , and hybrid nanofluids to investigate the heat transfer rates. Finally, the performance of SPHE using hybrid nanofluid is compared with that of using water and nanofluids. The heat transfer augmentation of approximately 16%‐27% with hybrid nanofluids of overall 4% nanoparticles volume concentration and 10%‐16% with 2% nanoparticles volume concentration is observed when compared with that of pure water. Therefore, it can be inferred that the application of hybrid nanofluids in SPHE seems to be one of the promising solutions for augmentation of its thermal performance.
Teenage Childbearing, Reproductive Justice, and Infant Mental Health
Authors: Hans Sydney L. , White Barbara A. 
Published: July 2019

ABSTRACTReproductive justice advocates emphasize the rights of women to choose to have children, to decide the conditions under which they give birth, and to parent their children with support, safety, and dignity. This article examines what a reproductive justice perspective contributes to infant mental health work with teenage mothers and their families. It explores the historical framing of teenage pregnancy in which young mothers are the cause of a variety of social problems and in which the primary policy and practice approach is pregnancy prevention. The article offers alternative framings of teenage childbearing, based on reproductive justice principles, which focus on social conditions surrounding teenage parenthood and the meaning of motherhood in the lives of young women. These alternative frames shift the practice agenda to eradicating unjust social conditions and providing supports for young women in their roles as parents. The article then describes ways in which two infant mental health programs have incorporated reproductive justice principles into their work with young families: Chicago's community doula model and Florida's Young Parents Project for court‐involved teenage parents. Finally, the article extracts a set of principles deriving from a reproductive justice perspective that are relevant to infant mental health work with young families.
GATA‐3 in T‐cell lymphoproliferative disorders
Authors: Murga‐Zamalloa Carlos , Wilcox Ryan A. 
Published: July 2019

AbstractGATA‐3 regulates the differentiation, proliferation, survival, and function of peripheral T cells and their thymic progenitors. Recent findings, reviewed here, not only implicate GATA‐3 in the pathogenesis of molecularly, genetically, and clinically distinct T‐cell lymphoproliferative disorders, but also have significant diagnostic, prognostic, and therapeutic implications.
Circular RNA hsa_circRNA_103809 promoted hepatocellular carcinoma development by regulating miR‐377‐3p/FGFR1/ERK axis
Authors: Zhan Wei , Liao Xin , Chen Zhongsheng , Li Lianghe , Tian Tian , Yu Lei , Wang Wei , Hu Qiyan 
Published: July 2019

AbstractIn the last decade, circular RNAs (circRNAs) emerge as important regulators in multiple biological processes. Lately, it is reported hsa_circRNA_103809 could play vital parts in several types of cancers. Based on the analysis of GEO data (GSE97332), hsa_circRNA_103809 was found to be dysregulated in hepatocellular carcinoma (HCC). However, the biological function and underlying regulatory mechanisms of hsa_circRNA_103809 in HCC remain unclear. Our results suggested that hsa_circRNA_103809 was overexpressed in HCC patients, and hsa_circRNA_103809 knockdown remarkably inhibited the proliferation, cycle progression, and migration of HCC cells. The investigations of molecular showed that hsa_circRNA_103809 could elevate the protein expression of a miR‐377‐3p target, fibroblast growth factor receptor 1 (FGFR1), through interacting with miR‐377‐3p and decreasing its expression level. Additionally, in vivo assays revealed hsa_circRNA_103809 short hairpin RNA served as a tumor suppressor through downregulating FGFR1 in HCC. This study systematically investigated novel regulatory signaling of hsa_circRNA_103809/miR‐377‐3p/FGFR1 axis, providing insights into hepatocellular carcinoma treatment from bench to clinic.
Role of linear endosonography in the diagnosis of biopsy‐negative malignant esophageal strictures: Exploring the unexplored
Authors: Dahale Amol S , Srivastava Siddharth , Sonika Ujjwal , Dalal Ashok , Goyal Aditi , Sakhuja Puja , Sachdeva Sanjeev , Puri Amarender S 
Published: July 2019

Background and AimEndoscopic biopsy is standard for the diagnosis of esophageal malignancy. However, few cases present with smooth stricture with repetitive negative biopsy results. We aimed to use linear endoscopic ultrasound (EUS) and fine‐needle aspiration (FNA) in the diagnosis of biopsy‐negative suspected malignant esophageal strictures.MethodsWe retrospectively analyzed the data from August 2017 to December 2018 of biopsy‐negative esophageal strictures. All adult patients with twice‐negative biopsies and with smooth overlying esophageal mucosa on endoscopy were included. Clinical, epidemiological, endoscopic, imaging, and EUS findings were noted and analyzed.ResultsEighteen patients underwent EUS for suspicion of malignant esophageal stricture. Seven were excluded as they were submucosal tumors. Eleven patients showed the presence of malignancy on EUS FNA samples. Nine were males. Computed tomography showed esophageal wall thickening in eight (16–38 mm) and esophageal mass in three patients. EUS showed loss of a normal five‐layered wall structure of the esophagus in all patients. Fine‐needle aspiration cytology demonstrated squamous cell carcinoma (n = 4), adenocarcinoma (n = 4), poorly differentiated carcinoma (n = 2), and neuroendocrine carcinoma (n = 1). There were no complications.ConclusionEUS with FNA is effective and safe for the diagnosis of biopsy‐negative malignant esophageal strictures.
Synthesis and Anticancer Evaluation of Some Novel Thiophene, Thieno[3,2‐d]pyrimidine, Thieno[3,2‐b]pyridine, and Thieno[3,2‐e][1,4]oxazepine Derivatives Containing Benzothiazole Moiety
Authors: Hassan Aisha Y. , Husseiny Ebtehal M. 
Published: July 2019

In an attempt to establish novel candidate with promising anticancer activity, two derivatives of (benzo[d]thiazol‐2‐yl)thiophene backbone 1 and 14 were synthesized, and they further reacted with various chemical reagents to afford the corresponding substituted thiophene derivatives 6, 8, 10, 15, 17, and 20, thieno[3,2‐d]pyrimidine derivatives 2–5, 7, 9, 16, 21, 23, and 24, thieno[3,2‐b]pyridine derivatives 11–13, and thieno[3,2‐e][1,4]oxazepine derivative 18. Structures of prepared compounds were affirmed via spectral and elemental data. Among the obtained compounds, seven derivatives 2, 3, 4, 5, 11, 12, and 13 were chosen by National Cancer Institute, USA. Such compounds were screened for their antitumor activity versus 60 cancer cell lines in one‐dose (10 μmol) screening assay. The outcomes showed that all selected compounds exhibited moderate to high anticancer activity towards many cancer cell lines among which compounds 5 and 11 exerted potent antitumor activity against numerous malignant growth cell lines particularly Ovarian Cancer IGROV1.
Change management for radiation therapists – transitioning to the new Royal Adelaide Hospital
Authors: Sale Charlotte , Page Deborah , Penniment Michael 
Published: July 2019

AbstractOne of the largest change operations to take place in South Australia was the moving of the Royal Adelaide Hospital (RAH) to its new site in 2017. Change can influence workplace effectiveness and staff satisfaction and morale. Understanding the stages of change, staff experience and carefully managing the process is important. This paper aims to describe the successful move of the radiation therapy department at the RAH to its new site, focusing on the staff experience and management strategies to ensure the success of the move. A four‐stage model of change was used to guide understand, manage and reflect upon the transition of the RAH radiation therapy department to a new site. Key change events and management strategies are described and aligned with the four stages of change. The move to the new site was a great success with a transition period working across two sites enabling a slower ramp up of activity at the new site supporting staff and patients in adjusting to the new environment. The four‐stage model of change assisted in the smooth implementation of a transition plan for radiation oncology. At the RAH, innovation and development are encouraged, along with management having a comprehensive understanding of organisational change enabling the radiation oncology department to successfully navigate rapid change.
Overexpression of the saccharopine dehydrogenase gene improves lysine biosynthesis inFlammulina velutipes
Authors: Liu Jianyu , Li Qiaozhen , Jiang Peiyu , Xu Zhen , Zhang Dan , Zhang Lujun , Zhang Meiyan , Yu Hailong , Song Chunyan , Tan Qi , Shang Xiaodong , Wang Ruijuan 
Published: July 2019

AbstractSaccharopine dehydrogenase (EC 1.5.1.7) regulates the last step of fungal lysine biosynthesis. The gene (Fvsdh) encoding saccharopine dehydrogenase was identified and cloned from the whole genome ofFlammulina velutipes. The genomic DNA ofFvsdhis 1257 bp, comprising three introns and four exons. The full‐length complementary DNA ofFvsdhcomprises 1107 bp with a deduced amino acid sequence of 368 residues. A 1,000‐bp promoter sequence containing the TATA box, CAAT box, and several putativecis‐acting elements was also identified. The results of tissue expression analysis showed that the expression level of theFvsdhgene was higher in the pileus than in the stipe whether in the elongation or maturation stage. Further research showed that the lysine contents were 3.03 and 2.95 mg/g in maturation‐pileus and elongation‐pileus, respectively. In contrast, the lysine contents were 2.49 and 2.07 mg/g in elongation‐stipe and maturation‐stipe, respectively. To study the function ofFvsdh, we overexpressedFvsdhinF. velutipesand found thatFvsdhgene expression was increased from 1.1‐ to 3‐fold in randomly selected transgenic strains. The lysine contents were also increased from 1.12‐ to 1.3‐fold in these five transformants, except for strain T3, in which the lysine contents were the same as the control. These results indicate that the expression of theFvsdhgene can affect the lysine content ofF.velutipes.
Raman study of nonhydrostatic pressure‐induced phase transitions in monoclinic L‐aspartic acid crystals
Authors: Fu Chao , Du Bing , Dai Chao , Li Pan , Lei Li , Xie Miaojia , Jiang Zhuo 
Published: July 2019

AbstractTo explore the properties of the L‐aspartic acid crystal structure under high pressure, we employed Raman spectra combined with vibrational mode assignments at pressures ranging from atmospheric pressure to 20.1 GPa. A comparison of the assignment of the vibration mode by density functional theory calculations and by isotopic shift measurements was also discussed. The spectra showed that modifications might be present mainly at pressures less than 10.0 GPa. Variations in the whole spectrum indicated that the crystal underwent three phase transitions at the pressure ranges of 2.2‐3.6, 5.2‐6.6, and 9.4‐10 GPa. A molecular conformational variation might occur at 14.3‐15.9 GPa. The behaviour of the wavenumber as a function of pressure was also presented. This work provides useful information on the hydrogen bonds within the stable monoclinic crystal structure of L‐aspartic acid.