bluuebunny/crossref_metadata_2025_split huggingface dataset:
Durch blaues Licht induzierte Carbentransferreaktionen von Diazoalkanen
Authors: Hommelsheim Renè , Guo Yujing , Yang Zhen , Empel Claire , Koenigs Rene M. 
Published: November 2018

AbstractCarbene sind wichtige reaktive Intermediate, die den Zugang zu einer Vielzahl von komplexen Molekülen ermöglichen und eine große Anwendung in der organischen Chemie und der Wirkstoffforschung besitzen. In der Regel wird diese Chemie durch die Verwendung von Übergangsmetallkatalysatoren ermöglicht. Im Folgenden beschreiben wir die Anwendung von niederenergetischem Licht zur photochemischen Erzeugung von Carbenen ausgehend von Donor‐Akzeptor‐Diazoalkanen. Dieser katalysatorfreie und präparativ einfache Ansatz ermöglicht hoch effiziente Cyclopropenierungsreaktionen von Alkinen und Umlagerungsreaktionen von Sulfiden unter milden Reaktionsbedingungen in einem diskontinuierlichen oder kontinuierlichen Prozess.
A Synthetic Polyester from Plant Oil Feedstock by Functionalizing Polymerization
Authors: Liu Ye , Mecking Stefan 
Published: November 2018

AbstractCatalytic functionalization/polymerization of castor oil‐derived undecenol yields an aliphatic polyester in a single step under mild conditions. The key to selective formation of linear high melting polyester is highly active carbonylation catalysts that at the same time do not undergo strong isomerization.
Guideline Implementation: Safe Patient Handling and Movement
Authors: Link Terri 
Published: November 2018

AbstractPhysical stressors that occur with patient and equipment handling in the OR (eg, moving or lifting patients, carrying heavy instrument sets, prolonged standing) can contribute to musculoskeletal disorders for perioperative personnel. In addition to increasing patient safety, safe patient handling and movement (SPHM) programs have been shown to reduce the risk and severity of injuries, workers’ compensation costs, and personnel fatigue and to increase health care workers’ morale and quality of life. The AORN “Guideline for safe patient handling and movement” provides guidance for implementing an SPHM program. This article discusses key takeaways from the guideline, including forming an interdisciplinary team to oversee the SPHM program, selecting safe patient handling technologies and equipment, and assessing the unique needs of each patient to develop an individualized plan for SPHM. Perioperative RNs should review the complete guideline for additional information and for guidance when writing and updating policies and procedures.
Remote Video Auditing to Verify OR Cleaning: A Quality Improvement Project
Authors: Armellino Donna , Dowling Oonagh , Newman Sheldon B. , Schwarz Richard B. , Jacobs Mitchel , Cifu‐Tursellino Kelly , Di Capua John F. 
Published: November 2018

AbstractThere are many sources of contamination in the perioperative environment. Patient experience can be negatively affected by the presence of environmental contamination, especially if it is the cause of a surgical site infection. Perioperative and environmental services staff members and leaders are tasked with ensuring a clean and safe environment for their patients while maintaining an awareness of time and budgetary constraints. In addition, leaders are responsible for the competency of their staff members and must address performance issues when needed. New technological advances designed to streamline monitoring and reporting processes related to OR cleanliness are available for use. This article describes the quality improvement project that one multifacility organization completed related to the use of remote video auditing and the positive effect it had on the organization's environmental contamination.
Tricolor Luminescence Switching by Thermal and Mechanical Stimuli in the Crystal Polymorphs of Pyridyl‐substituted Fluorene
Authors: Guan Jianping , Xu Fan , Tian Chang , Pu Liang , Yuan Mao‐Sen , Wang Jinyi 
Published: November 2018

AbstractStimuli‐responsive organic luminescence‐switching materials have attracted much attention for a decade. Most of the reported examples display a reversible two‐color luminescence switching, and multicolor‐switching materials remain extremely rare. Herein, we report a simple organic molecule, 4,4′‐(9,9‐dimethyl‐9H‐fluorene‐2,7‐diyl)dipyridine (MFDP), which exhibits three different crystal polymorphs (V‐MFDP, B‐MFDP and G‐MFDP) with different luminescent colors. Furthermore, the three crystal polymorphs show a reversible tricolor fluorescent switching from violet to blue and to green upon physical stimuli. The single‐crystal structures of the three polymorphs were obtained, and the results indicate that the stimuli‐responsive properties of the three polymorphs come from the different stacking modes induced by intermolecular interactions. The competition between weak π–π stacking and weak hydrogen bonding is the main reason for the the phase transformations among the three crystal polymorphs.
Recursive Bayesian state estimation method for run‐to‐run control in high‐mixed semiconductor manufacturing process
Authors: Tan Fei , Pan Tianhong , Bian Jun , Wang Haiyan , Wang Weiran 
Published: November 2018

AbstractOne of the challenges in semiconductor manufacturing processes is the state estimation of a high‐mix production system. The traditional algorithm consists of constructing a context matrix based on the product fabricating thread. The state of the context matrix is estimated using the Moore‐Penrose pseudo‐inverse method. Although the method works well, the context matrix is often singular. Taking an integrated moving average disturbance into consideration, a novel state estimation method is proposed in a high‐mix manufacturing scenario. Furthermore, the recursive Bayesian estimation is presented to obtain the estimations of states combined with a moving window and an analysis of variance model. As a result, the calculation of the inverse of the context matrix is avoided and the unobservability problem is addressed. Both simulated and industrial cases are presented to demonstrate the effectiveness of the proposed algorithm.
Septal rupture closure: Still a challenge
Authors: Kamioka Norihiko , Block Peter C. 
Published: November 2018

Key Points
Review of the Medicare database shows that over the past 16 years the incidence of post‐ myocardial infarction (MI) ventricular septal rupture (VSR) has decreased but mortality for all post‐MI VSR hospitalizations remains unchanged and high
During the study period, the 30‐day VSR repair rate decreased from 49.9% in 1999 to 33.3% in 2014. Unadjusted mortality was lower for patients undergoing repair procedures than for those not undergoing repair both at 30 days and at 1‐year.
Most VSR patients underwent surgical repair (82.9%) and only a minority underwent transcatheter repair (17.1%). Regardless of the approach, outcomes remain unsatisfactory.
Non‐femoral TAVR: Time to stratify alternative vascular approaches
Authors: Guedeney Paul , Mehran Roxana 
Published: November 2018

Key Points
Although transfemoral transcatheter aortic valve replacement (TAVR) is the gold standard, this approach is not be feasible in approximately 15% of the patients.
Trans‐carotid TAVR may be less invasive than transthoracic routes for TAVR, and has been associated with encouraging results.
Further prospective studies comparing alternative access routes in patients with whom transfemoral TAVR is not feasible are warranted, to propose an evidence‐based algorithm guiding the physician decision.
Using the Terms Experiment, Theory, Model, and Law in Mathematics and Natural Sciences
Authors: Reiners Christiane S. , Großschedl Jörg , Meyer Michael , Schadschneider Andreas , Schäbitz Frank , Struve Horst 
Published: November 2018

AbstractNaturwissenschaftliche Bildung impliziert ein angemessenes Verständnis zentraler Begrifflichkeiten, die den Weg der Erkenntnisgewinnung in den mathematisch‐naturwissenschaftlichen Fächern kennzeichnen. Im Rahmen der Nature‐of‐Science‐Forschung konnte ein Konsens über wesentliche Merkmale von Begriffen wie „Experiment“, „Theorie“, „Modell“ und „Gesetz“ für den schulischen Bereich erzielt werden. Die fachspezifischen Besonderheiten in der aktuellen mathematisch‐naturwissenschaftlichen Theorie und Praxis bleiben dabei allerdings ausgeblendet. Um diesen näher zu kommen, wurden einerseits innerhalb der einzelnen Disziplinen literaturbasierte Begriffsbestimmungen zusammengestellt, andererseits wurden Interviews mit fachwissenschaftlichen Kollegen durchgeführt. Die Literaturanalyse verweist auf Unterschiede in der Bedeutung der Begriffe in den einzelnen naturwissenschaftlichen Fächern und der Mathematik. Weitaus deutlichere Inkonsistenzen und Widersprüche zeigen sich jedoch im Gebrauch der Begriffe durch die Wissenschaftler in diesen Fächern. Die Ergebnisse werden in diesem Artikel vorgestellt und dienen als Ausgangspunkt für entsprechende Konsequenzen in der Lehrerbildung.
Fine needle aspiration cytology in Mozambique: Report of a 15‐year experience
Authors: Carrilho Carla , Ismail Mamudo , Lorenzoni Cesaltina , Fernandes Fabíola , Alberto Matos , Akrami Kevan , Funzamo Carlos , Lunet Nuno , Schmitt Fernando 
Published: November 2018

BackgroundFine needle aspiration cytology (FNAC) is an important diagnostic tool in a range of medical settings. It is fast, quick and a highly accurate diagnostic method and can be used, in settings with minimal laboratory infrastructures.MethodsIn this report, we describe the experience in the use of FNAC since it is introduction in 1996 in the Anatomical Pathology Service of the Maputo Central Hospital (MCH), along with more detailed data referring to 2009‐2010.ResultsThe number of FNAC analyses increased gradually from 269 (4.1% of all pathologic tests of the Service) in 1996, when it was introduced in Mozambique, to 3234 (17% of all tests) in 2010. Lymph nodes were the organs most frequently biopsied, followed by breast and soft tissues. Inflammatory conditions, especially tuberculosis, were the most frequent diagnoses (22.2% of the cases), followed by hyperplastic conditions (20.6%), benign tumors (13.4%) and malignant tumors (12.3%).ConclusionOur results clearly demonstrate that even in an environment with poor laboratory resources, it is possible to establish a FNAC clinic that can provide a quick and precise diagnosis for clinicians to aid in early treatment interventions, especially in inflammatory diseases which were the majority of our cases.
Freeing the data from cytology databases in order to improve the quality of cytology
Authors: Renshaw Andrew A. , Birdsong George G. 
Published: November 2018

IntroductionTo review how changes in data storage and analysis can impact quality and quality assessment in cytology.MethodsReview of the literature.ResultsAll quality assessment is dependent on the data available for review and the methods available for evaluation. Current laboratory information systems (LISs) incorporate both a relational or hierarchical database and built in methods to analyze current quality assessment standards. In contrast, most information systems outside of medicine are separating data storage from analysis, allowing increasingly more sophisticated forms of evaluation.ConclusionThere is an opportunity for improvement in cytology by improving the way data can be extracted and analyzed from the cytology LIS.
Double standards in body evaluation? How identifying with a body stimulus influences ratings in women with anorexia nervosa and bulimia nervosa
Authors: Voges Mona M. , Giabbiconi Claire‐Marie , Schöne Benjamin , Braks Karsten , Huber Thomas J. , Waldorf Manuel , Hartmann Andrea S. , Vocks Silja 
Published: November 2018

AbstractObjectiveWomen with eating disorders (ED) evaluate their own body more negatively than do women without ED. However, it is unclear whether this negative rating is due to objective bodily features or different standards for one's own body and others' bodies. Therefore, the purpose of this study was to examine whether women with ED apply double standards when rating bodies by disentangling the objective features of one's own body from the feelings of ownership.MethodWe presented n = 34 women with anorexia nervosa, n = 31 women with bulimia nervosa, and n = 114 healthy controls with pictures of thin, average‐weight, overweight, athletic, and hypermuscular bodies. Identity was manipulated by showing each body once with the participant's own face and once with the face of another woman. Participants were instructed to report their emotional state according to valence and arousal and to rate body attractiveness, body fat, and muscle mass.ResultsWomen with anorexia nervosa and bulimia nervosa displayed greater self‐deprecating double standards in body fat rating than did women without ED, as quantified by the difference between the ratings of the same body with one's own versus another woman's face. Double standards reflected in valence, arousal and attractiveness ratings were significantly more pronounced in women with anorexia nervosa than in women without ED.DiscussionThe double standards found may be due to an activation of dysfunctional self‐related body schemata, which distort body evaluation depending on identity. Double standards related to body fat were characteristic for women with ED, but not for women without ED.
Recurrent hyponatremia in a young adult woman with anorexia nervosa and the effects of insufficient communication
Authors: Boyd Erin D. , Durant Nefertiti Harmon 
Published: November 2018

AbstractThis is the case of an 18‐year‐old young adult woman with anorexia nervosa (AN) who presented to the emergency department with complications from AN and was found to be hyponatremic. The hyponatremia was prioritized and corrected with fluids on hospital day one. The consulting adolescent medicine team recommended the primary inpatient medical team initiate the malnutrition protocol. Nephrology recommended fluid restriction. Despite initiation of this protocol and emphasis on protocol adherence with the primary team, patient, and family, the hyponatremia recurred. Retrospectively, there were three factors that led to her recurrent hyponatremia: inconsistencies in protocol adherence across medical clinical providers, lack of knowledge regarding the importance of adherence to the malnutrition protocol, and suboptimal communication between medical clinical providers. A multidisciplinary team experienced in the care of patients with AN may enhance inpatient treatment of this condition. A multidisciplinary team experienced in AN will have a better understanding of the complexities of AN, skill in protocol implementation, understand the importance of protocol adherence, and be more likely to clearly communicate the plan of care to the patient/family. These skills can lead to improved care quality, decreased risk of adverse outcomes, and likely decreased medical costs.
Post‐discharge short message service improves short‐term clinical outcome and self‐care behaviour in chronic heart failure
Authors: Chen Chen , Li Xiao , Sun Lisha , Cao Sha , Kang Yu , Hong Liu , Liang Yaodan , You Guiying , Zhang Qing 
Published: November 2018

AbstractAimsIn addition to giving optimal medical and device therapy, promoting self‐care of chronic heart failure (CHF) patients also plays an important role in comprehensive disease management for better outcomes. The study was aimed to investigate whether short message service (SMS) would help to improve death or readmission‐free survival and self‐care behaviour in CHF patients.Methods and resultsThis was a randomized controlled trial. Between December 2011 and September 2015, patients admitted with decompensated CHF in a tertiary referral hospital who fulfilled the inclusion criteria were enrolled and randomized to receive SMS, structured telephone support (STS), or usual care after discharge. All patients were followed up to 180 days after discharge by phone call or clinic visit. Primary endpoint was the 180 day composite event, defined as all‐cause mortality or readmission. Secondary endpoints included self‐care behaviour and quality of life. Seven hundred sixty‐seven patients (61 ± 15 years, 56.5% male) were finally randomized to receive SMS (n = 252), STS (n = 255), or usual care (n = 260). Baseline characteristics were similar among the three groups. Five hundred twenty‐five (68.4%) patients were in New York Heart Association Class III or IV, and 472 (61.5%) patients had an ejection fraction of <50%. During a 180 day follow‐up, 76 (9.9%) patients died and 274 (35.7%) patients experienced at least one readmission. In a short‐term follow‐up of 30 days, there was no difference in mortality and the composite endpoint among the three groups (SMS vs. STS vs. usual care: 2.8% vs. 3.1% vs. 3.8% for mortality, P = 0.786; 12.3% vs. 14.5% vs. 15.4% for the composite endpoint, P = 0.588). The 180 day composite event rate was significantly lower in the SMS and STS groups (50.4% vs. 41.3% and 36.5%, both P < 0.05) than in the usual care group, but no difference was observed between the two phone‐based intervention groups (P = 0.268). Although there was no difference between the two groups, better self‐care behaviour was reported in the SMS and STS groups than in the control group (medication compliance, 78.9% vs. 81.4% vs. 69.5%, P = 0.011; water restriction, 70.8% vs. 74.5% vs. 61.5%, P = 0.013). Quality‐of‐life score was similar among the three groups at 180 days (P = 0.526).ConclusionsIn CHF patients, post‐discharge SMS, which appeared as efficient as STS, reduced the 180 day composite event and improved self‐care behaviour. SMS intervention could be integrated into CHF management.
Exposures of children to neonicotinoids in pine wilt disease control areas
Authors: Ikenaka Yoshinori , Miyabara Yuichi , Ichise Takahiro , Nakayama Shouta , Nimako Collins , Ishizuka Mayumi , Tohyama Chiharu 
Published: November 2018

Abstract

Neonicotinoid insecticides that have been on the market since 1992 have been used globally including in Japan. Because they are sprayed over forests and agricultural areas, inadvertent toxicity in nontarget insects (especially honey bees) and humans is a matter of public concern. However, information on exposure levels and potential health impacts of neonicotinoids in children living around sprayed areas is scarce. Thus, we determined neonicotinoid exposure levels in children living in communities where thiacloprid was used to control pine wilt disease. A total of 46 children (23 males and 23 females) were recruited for the present study, and informed written consent was obtained from their guardians. Urine specimens were collected before, during, and after insecticide spraying events; and atmospheric particulate matter was also collected. Concentrations of thiacloprid and 6 other neonicotinoid compounds were determined in urine samples and in atmospheric particulate matter specimens using liquid chromatography-electrospray ionization-tandem mass spectrometry. In urine specimens, thiacloprid concentrations were &lt;0.13 μg/L and were detectable in approximately 30% of all samples. Concentrations of the other neonicotinoids, N-dm-acetamiprid, thiamethoxam, dinotefuran, and clothianidin, were 18.7, 1.92, 72.3, and 6.02 µg/L, respectively. Estimated daily intakes of these neonicotinoids were then calculated from urinary levels; although the estimated daily intakes of the neonicotinoids were lower than current acceptable daily intake values, the children were found to be exposed to multiple neonicotinoids on a daily basis. Environ Toxicol Chem 2019;38:71–79. © 2018 SETAC
Cancer chromosome breakpoints cluster in gene‐rich genomic regions
Authors: Mitelman Felix , Johansson Bertil , Mertens Fredrik , Schyman Tommy , Mandahl Nils 
Published: November 2018

AbstractCancer cells are characterized by chromosome abnormalities, of which some, in particular balanced rearrangements, are associated with distinct tumor entities and/or with specific gene rearrangements that represent important steps in the carcinogenic process. However, the vast majority of cytogenetically detectable structural aberrations in cancer cells have not been characterized at the nucleotide level; hence, their importance and functional consequences are unknown. By ascertaining the chromosomal breakpoints in 22 344 different clonal structural chromosome abnormalities identified in the karyotypes of 49 626 cases of neoplastic disorders we here show that the distribution of breakpoints is strongly associated (P < 0.0001) with gene content within the affected chromosomal bands. This association also remains highly significant in separate analyses of recurrent and nonrecurrent chromosome abnormalities as well as of specific subtypes of cancer (P < 0.0001 for all comparisons). In contrast, the impact of band length was negligible. The breakpoint distribution is thus not stochastic—gene‐rich regions are preferentially affected. Several genomic features relating to transcription, replication, and chromatin organization have been found to enhance chromosome breakage frequencies; this indicates that gene‐rich regions may be more break‐prone. The salient finding in the present study is that a substantial fraction of all structural chromosome abnormalities, not only those specifically associated with certain tumor types, may affect genes that are pathogenetically important. If this interpretation is correct, then the prevailing view that the great majority of cancer chromosome aberrations is cytogenetic noise can be seriously questioned.
Antipsychotic use and related factors among people with dementia aged 75 years or older in Japan: A comprehensive population‐based estimation using medical and long‐term care data
Authors: Kuroda Naoaki , Hamada Shota , Sakata Nobuo , Jeon Boyoung , Iijima Katsuya , Yoshie Satoru , Ishizaki Tatsuro , Jin Xueying , Watanabe Taeko , Tamiya Nanako 
Published: November 2018

ObjectivesAntipsychotics are used to manage the behavioral and psychological symptoms of dementia (BPSD), despite their association with greater risks for mortality and cerebrovascular events. Previous studies in Japan have estimated the prevalence of antipsychotics among older adults who took antidementia drugs. Using long‐term care (LTC) data, we aimed to obtain more accurate estimates of the prevalence of antipsychotics and to determine factors related to their use in older adults with dementia.MethodsMedical and LTC claims data and LTC certification data between April 2012 and September 2013 were obtained from a middle‐sized suburban city. The 1‐year prevalence of antipsychotic use was estimated among individuals with probable dementia aged greater than or equal to 75 years who were prescribed antidementia drugs and/or had dementia based on LTC needs certification data.ResultsOf 25 919 participants, 4865 had probable dementia and 1506 were prescribed antidementia drugs. The prevalence of antipsychotics among participants with probable dementia was 10.7%, which was lower than that in those who were prescribed antidementia drugs (16.4%). Among participants with probable dementia with LTC certification data available (N = 4419), lower cognitive function (vs mild; adjusted odds ratio 2.16, 95% confidence interval 1.63‐2.86), antidementia drug use (2.27, 1.84‐2.81), and institutional LTC services use (2.34, 1.85‐2.97) were associated with greater odds of antipsychotic use, whereas older age (greater than or equal to 92 years) was associated with lower odds (vs less than 77 years; 0.42, 0.27‐0.65).ConclusionsThese findings may be useful for estimating the burden of BPSD and for taking measures to reduce inappropriate antipsychotic prescription.