bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decoding G0 somatic mutants through deep phenotyping and mosaic pattern analysis in the zebrafish skeleton
Authors: Watson Claire J. , Monstad-Rios Adrian T. , Bhimani Rehaan M. , Gistelinck Charlotte , Willaert Andy , Coucke Paul , Hsu Yi-Hsiang , Kwon Ronald Y. 
Published: November 2018

ABSTRACTGenetic mosaicism manifests as spatially variable phenotypes, whose detection and interpretation remains challenging. This study identifies biological factors influencing spatial phenotypic patterns in the skeletons of somatic mutant zebrafish, and tests methods for their analysis using deep phenotyping. We explore characteristics of loss-of-function clusters in the skeleton of CRISPR-edited G0 ("crispant") zebrafish, and identify a distinctive size distribution shown to arise from clonal fragmentation and merger events. Using microCT-based phenomics, we describe diverse phenotypic manifestations in somatic mutants for genes implicated in monogenic (plod2 and bmp1a) and polygenic (wnt16) bone diseases, each showing convergence with germline mutant phenomes. Finally, we describe statistical frameworks for phenomic analysis which confers heightened sensitivity in discriminating somatic mutant populations, and quantifies spatial phenotypic variation. Our studies provide strategies for decoding spatially variable phenotypes which, paired with CRISPR-based screens, can identify genes contributing to skeletal disease.
The role of substrate type, moisture and temperature on the vertical growth of terricolous lichens
Authors: Monge-Nájera Julián 
Published: November 2018

AbstractLichens are traditionally divided into short “crustose”, intermediate “foliose” and tall “fruticose” types, a practice that hides a growth continuum. Substrate, temperature and water are thought to affect vertical growth, but such factors are difficult to measure, because, for example, the water actually available to lichens does not match rainfall patterns or even ground water levels. To reliably assess the effect of those factors, I recorded temperature, moisture, and substrate in and under individual terricolous lichen colonies in 60 fixed quadrats on April, August, October, and December of 2015 (Cerro de la Muerte, Costa Rica, 9°33′N; 83°45′W). The measurements were taken inside the colonies themselves (rather than on the general environment), covering an annual cycle of the relatively simple páramo habitat, where animals and vegetation have less impact than in lower ecosystems. The hypotheses were that lichens would grow taller on softer, warmer, and moister ground; on the Caribbean versant; and on the rainy season. Results matched the hypotheses, with one exception: lichens on soft ground were not taller than those on rock. Caribbean colonies were, on the average, 7 cm taller than those on the drier Pacific versant. Physiologically available water seems to be the main determinant of lichen vertical growth: more water means taller lichens and greater protection from climatic change for both the lichens and their microcommunities.
Crops and the seed mass-seed output trade-off in plants
Authors: Martin Adam R. 
Published: November 2018

AbstractA trade-off between seed mass (SM) and seed output (SO) defines a central axis of ecological variation among plants, with implications for understanding both plant trait evolution and plant responses to environmental change. While an observed negative SM-SO relationship is hypothesized to reflect universal constraints on resource allocation in all plants, domestication has likely fundamentally altered this relationship. Using a dataset of SM and SO for 41 of the world most widespread crops and 1,190 wild plant species, coupled with observational data on these traits in soy (Glycine max) and maize (Zea mays), I show that domestication has systematically rewired SM-SO relationships in crops. Compared to wild plants, virtually all crops express a higher SM for a given SO; this domestication signature is especially prominent in seed crops, and also influences the phylogenetic signal in SM and SO. In maize these traits have become positively related likely due to simultaneous selection for greater SM and SO, while in soy these traits have become decoupled likely due to primary selection for SM only. Evolved relationships between SM and SO in plants have been disrupted by both conscious and unconscious artificial selection, which represents a key aspect of how the functional biology of crops differ fundamentally from wild plants along “universal” plant trait spectra.
Electro chemical impedance spectroscopy (EIS) study of modified SS316L using radio frequency sputtering Ti6Al4V coating in Ringer solution
Authors: Siyah Murtdha Adhab , Moradian Rostam , Manouchehri Iraj 
Published: November 2018

PurposeSS316L alloy used in biomedical application and the alloy have Fe, Cr and Ni elements and release this ion into the human body causing dangerous effects for the human body, and make the SS316L, which is used as surgical implant failure in short time in biomedical application. This study aims to use Ti6Al4V as coating for SS316L alloy to make it have bio inert surface, and modified the surface alloy for biomedical application from another part in this study, we want to decrease the corrosion rate for SS316L in simulated body surface Ringer solution.Design/methodology/approachThe morphology, roughness, XRD of the coating, potential polarization and electrochemical impedance spectra investigation to study the effect of Ti6Al4V coating on corrosion behaviors of SS316L in the Ringer solution.FindingsThis study discusses the modification of SS316L surfaces by using Ti6Al4V radio magnetron frequency sputtering techniques, the results of the EIS and polarization of SS316L in Ringer’s solution at 37°C shows that improved resistance against corrosive ions for all the samples coating with Ti6Al4V and especially with a coating have a thickness of 850 nm at a sputtering power of 150 W.Research limitations/implicationsPolarization and electro chemical impedance spectra were assessed to investigate the effect of Ti6Al4V coating on corrosion behaviors of SS316L alloy in the Ringer solution.Practical implicationsThis study discussed the modification SS316L surfaces by using Ti6Al4V radio magnetron frequency sputtering techniques. The results of the EIS and polarization of SS316L in Ringer’s solution at 37°C improved resistance against corrosive ions for all the samples coating with a Ti6Al4V and specificity with the coating sample have a thickness 850 nm at a sputtering power of 150 W.Social implicationsThe goal of this study to modification SS316L alloy surface by using Ti6al4V RF Sputtering to give the SS316L alloy more resistance for biocorrosion.Originality/valueIn this research, Ti6Al4V RF sputtering as a coating for SS316L, study the bio corrosion behaviors in Simulated body fluid Ringer solution and investigation the corrosion by using EIS analysis.
Exploration on factors influencing Korean diaspora entrepreneurs’ investment in the homeland
Authors: Park Choo-Hui , Chu Hankyu 
Published: November 2018

Purpose
The Government of Korea institutionalized the World Korean Business Convention (WKBC) and the World Korean Business Network (WKBN) to promote Korean diaspora entrepreneurs’ investment in the homeland. Few studies have examined the effectiveness of the WKBC and WKBN and the critical variables affecting them. This paper aims to fill this gap by exploring important variables affecting Korean diaspora entrepreneurs’ investment in the homeland. It also seeks to examine the relationships among these variables to inquire upon a set of critical questions pertaining to Korean diaspora entrepreneurs’ investment in the homeland including the effectiveness of the WKBC and WKBN.

Design/methodology/approach
To achieve the above purpose, critical variables influencing Korean diaspora entrepreneurs’ investment in the homeland were identified and four hypotheses that include the inquiries pertaining to the effectiveness of the WKBC and WKBN were developed in terms of those variables. The hypotheses were empirically tested using the survey data gathered from the participants of the annual WKBC.

Findings
The current research found that Korean diaspora entrepreneurs’ evaluation of the investment climate in the homeland was not favorable. The WKBC was positively evaluated by Korean diaspora entrepreneurs willing to make investment, There is discrepancy between expectations of the WKBN’s target group (i.e. Korean diaspora entrepreneurs willing to make investment) and its performance for the group, and there is a difference between ascending and descending Korean diaspora entrepreneurs in assessment of investment value of the homeland.

Originality/value
A majority of studies on diaspora entrepreneurship and development have so far cast light on ascending diaspora entrepreneurs while neglecting descending diaspora entrepreneurs. In this regard, the most interesting finding of the current study to both researchers and policymakers may be the fact that descending Korean diaspora entrepreneurs assess the investment value of the homeland differently from ascending Korea diaspora entrepreneurs. The finding calls for further research on causes of the difference, and different natures of descending diaspora entrepreneurs compared to those of ascending diaspora entrepreneurs. Such research will enable policymakers to formulate and implement effective strategic diaspora policies that take the differences into consideration.
Effect of hot obstacle position on natural convection heat transfer of MWCNTs-water nanofluid in U-shaped enclosure using lattice Boltzmann method
Authors: Ma Yuan , Mohebbi Rasul , Rashidi Mohammad Mehdi , Yang Zhigang 
Published: November 2018

PurposeThis paper aims to numerically investigate the natural convection heat transfer of multi-wall carbon nanotubes (MWCNTs)-water nanofluid in U-shaped enclosure equipped with a hot obstacle by using the lattice Boltzmann method.Design/methodology/approachThe combination of the three topics (U-shaped enclosure, different positions of the hot obstacle and MWCNTs-water nanofluid) is innovative in the present study. In total, 15 different positions of the hot obstacle have been arranged, and the effects of pertinent parameters such as Rayleigh numbers, the solid volume fraction of the MWCNTs nanoparticles on the flow field, temperature distribution and the rate of heat transfer inside the enclosure are also investigated.FindingsIt is found that the average Nusselt number increased by raising the Rayleigh number, and so did the nanoparticle solid volume fraction regardless the position of the hot obstacle. Moreover, enclosures where the hot obstacle is located at the bottom region proved to provide a better rate of heat transfer at high Rayleigh number (106). It is concluded that at a low Ra number (103-105), the higher heat transfer rate and Nu number will be obtained when the hot obstacle is located in the left or right channel.Originality/valueIn the literature, no trace of studying the natural convection of nanofluids in U-shaped enclosures with heating obstacles was found. Also, MWCNTs were less used as nanoparticles. As the natural convection of nanofluids in thermal engineering applications would expand the existing knowledge, the current researchers conducted a numerical study of the natural convection of Maxwell nanofluid with MWCNTs in U-shaped enclosure equipped with a hot obstacle by using lattice Boltzmann method.
The impact of industrial self-supply on Bavaria’s electricity system – effects on supply security and market prices
Authors: Scheubel Christopher , Matthäus David , Friedl Gunther 
Published: November 2018

Purpose
The purpose of this paper is to analyze the role of industrial self-supply in the transition process from centralized energy generation based on fossil fuels and nuclear power to decentralized supply based on renewable energies in the Bavarian electricity system.

Design/methodology/approach
To quantify effects on system and price stability, a model of the Bavarian electricity grid is created and used to simulate electricity system behavior during a 1-year period for scenarios that are characterized by parameter variations in industrial self-supply, nuclear power capacity, renewable power generation and the capacity of electricity imports.

Findings
The simulations show that industrial self-supply can reduce instances of maximum grid utilization by 23 per cent and, based on the merit-order effect, decrease electricity market prices by 1.90 and 5.03 €/MWh in the scenarios with and without nuclear power, respectively; these values represent 5.7 and 15.0 per cent of average market prices from 2014.

Research limitations/implications
The analysis shows that industrial self-supply can contribute to transforming the electricity system in a secure, sustainable and affordable manner. However, merit-order-based price effects have a limitation concerning the future applicability of results as quantified effects may not be permanent when the electricity system adapts.

Originality/value
This paper connects industrial self-supply and the merit-order effect within a nodal energy model. It provides insights into the relevant interdependencies and reciprocal effects by means of a simulation.
Macro-level antecedents of consumer brand hate
Authors: Kucuk S. Umit 
Published: November 2018

Purpose
This study aims to discuss the antecedent roles that corporate social responsibility and consumer complaints perform in consumer brand hate and anti-branding activities.

Design/methodology/approach
The reasons for the existence of anti-brand websites and how they operate in dynamically changing digital platforms are discussed with a literature review and data analysis.

Findings
The findings of this study reveal that there is a direct link between consumer dissatisfaction and brand hate, and that there is a partially mediating impact by customer dissatisfaction and corporate social responsibility on consumer brand hate.

Originality/value
This study is the first-of-its-kind investigation of the relationships that might exist among corporate social responsibility, consumer complaints and dissatisfaction, consumer anti-branding and brand hate with macro-level indicators. The study is the first of its kind to test macro-level brand hate measures with a set of longitudinal analyses.
“Is sharing really caring?”
Authors: Wan Ismail Wan Rusni , Othman Mohhidin , Abdul Rahman Russly , Kamarulzaman Nitty Hirawaty , Ab Rahman Suhaimi Bin 
Published: November 2018

Purpose
The purpose of this paper is to investigate the extent and the impact of negative electronic word of mouth (eWoM) on Muslim consumers’ tolerance and to look for evidence on whether it can pose threat to high-tolerance products and cause spillover effect on products in similar category.

Design/methodology/approach
This study used a qualitative method with purposive sampling, and data were collected from 23 Malay Muslim consumers using in-depth interviews.

Findings
Findings from this study clearly showed that consumers’ perception toward effected products can easily be distorted with negative claim which indicates that halal issues are very sensitive to Muslim consumers. The negative eWoM distorts consumers’ perception toward effected product and the effect was also found to escalate into other brands that share similar category as the effected products.

Practical implications
By examining the negative impact of eWoM, it validates the severe impact it has on Muslim consumers, and it is quite obvious that no products are really safe from it, including high-tolerance products. Evidence from this study revealed the importance and the urgency for organizations to handle any rumors immediately because further delay can result from significant loses in sales and can tarnish the brand image.

Originality/value
Negative claims related to the halal product status often sparks negative reactions, especially among Muslim consumers, and despite frequent occurrence of such event, very little information is available on its impact on consumers’ tolerance. Certain products fall under safe product category, or high-tolerance products are also found to be vulnerable to negative impact of eWoM because once the consumers’ trust is shaken, confidence will be replaced by doubt, which often leads to loss of sales and loyalty. It is commonly known that effected products and brand will suffer from this event; however, spillover effect is another side effect of negative eWoM that is not yet highlighted in previous studies.
Investigating user continuance intention toward library self-service technology
Authors: Wu Chorng-Guang , Wu Pei-Yin 
Published: November 2018

Purpose
The purpose of this paper is to apply expectation-confirmation theory (ECT) and the unified theory of acceptance and use of technology (UTAUT) to identify potential determinants of library patrons’ intention to continue using (continuance) self-issue and return systems for borrowing and returning books. The role of continuance is specifically interesting and is well-established in the literature of information systems (ISs) and marketing because continuance is considered to be the central element for the survival of ISs and of self-service technology (SST). However, the role of continuance has been neglected by researchers studying library SST adoption.

Design/methodology/approach
A research model integrating the expectation-confirmation model of IS continuance with UTAUT was developed and empirically validated using data obtained from a field survey involving 128 active users of a self-issue and return system at a public library in Taiwan.

Findings
Library patrons’ continuance intention was affected by their post-adoption expectation of perceived performance, effort performance and facilitating conditions as well as their satisfaction when using self-issue and return systems. Moreover, a patron satisfaction level was influenced by performance expectancy and confirmation of initial expectations, whereas confirmation had a positive effect on all post-adoption expectations.

Originality/value
This study broadens perspectives on SST adoption behavior in the library context by identifying some factors that influence library patrons’ continuance decisions. Furthermore, the authors verified the applicability and predictability of the theoretical integration of ECT with UTAUT in a diverse setting because the authors sought survey participants outside of the college population.
Team effectiveness: the predictive role of team identity
Authors: Reis Daniela Pinheiro dos , Puente-Palacios Katia 
Published: November 2018

Purpose
The purpose of this study was to identify the explanatory power of the affective, cognitive and evaluative aspects of identity with work teams in predicting team effectiveness, represented by the variables: satisfaction with the team, manager-assessed team performance and objective indicators of performance.

Design/methodology/approach
Data were collected from 131 work teams of a Brazilian public organization with units in all state capitals of the country. Work team identity scale, the work team satisfaction scale, the team performance scale and objective performance indicators collected based on the achievement of the goals set for the units that make up the organization were used. To test the predictive model, three regressions were conducted using the stepwise method.

Findings
Regression analysis results showed that the evaluative dimension explains about 6% of the performance assessment given by managers, whereas the affective dimension explains 63% of the satisfaction with work teams. No significant results were found for the objective performance indicators.

Originality/value
The observed findings demonstrate the pertinence of understanding the work team identity as a collective and multidimensional phenomenon, as well as the contribution of its different components in explaining variables that represent effectiveness.
Inter‐populational variation, but no‐annual variation within populations, in terms of reproductive size and genetic structure in a monocarpic perennial herb, Cardiocrinum cordatum var. glehnii
Authors: Hayafune Takuma , Utech Frederick H. , Ohara Masashi 
Published: November 2018

AbstractCardiocrinum cordatum var. glehnii (Liliaceae) is a monocarpic perennial herb living in temperate broad‐leaved deciduous forests. In the present study we examined the sizes (basal diameter of the stem and flower numbers) of flowering individuals and genetic diversity using microsatellite loci of 23 populations of C. cordatum var. glehnii in Hokkaido, Japan, over 2 years (2009 and 2010). As a result, we found both the basal stem diameter and the number of flowers varied widely among the populations. However, although the sizes of flowering individuals differed among the populations, these were very stable in each population and in each year. In addition, for genetic diversity, the same trends (i.e. wide variation among the populations but non‐annual variation) were detected.
The Local Impacts of Agricultural Subsidies: Evidence from the Canadian Prairies
Authors: Bollman Ray D. , Ferguson Shon M. 
Published: November 2018

AbstractWe estimate the impact of removing an export subsidy on the local economies of Alberta, Saskatchewan and Manitoba, exploiting the large regional variation of a 1995 reform. We find that the loss of the subsidy resulted in significantly lower farm value‐added, farm asset values and local non‐farm employment. The results suggest that the subsidy removal had detrimental spillover effects on the local non‐agricultural economy that varied spatially across the Prairies. The point estimates suggest that the marginal effect of the subsidy loss on non‐agricultural employment was five times as large as those obtained from traditional estimates of the multiplier effect.
A qualitative study of quality of life domains and subdomains relevant to patients with spondyloarthritis
Authors: Kwan Yu Heng , Fong Warren , Leung Ying Ying , Tan Victoria Ie Ching , Yap Angela Frances , Phang Jie Kie , Lui Nai Lee , Yoon Sungwon , Malhotra Rahul , Thumboo Julian , Østbye Truls 
Published: November 2018

AbstractAimsTo identify quality of life (QoL) domains and subdomains relevant to patients with different spondyloarthritis (SpA) subtypes in Singapore, and to assess how identified QoL domains and subdomains map onto currently used patient‐reported outcome measures (PROMs).MethodsNine focus group discussions (FGDs), including two previously conducted FGDs from the Updating the Psoriatic Arthritis Core Domain Set Study, were conducted with patients with SpA in Singapore. The FGDs were organized by SpA subtype and language spoken. All FGDs were audio‐taped, transcribed verbatim. After thematic analysis through open and axial coding, the domains were organized using the World Health Organization Quality of Life (WHOQOL) framework. Identified QoL domains and subdomains were mapped to currently used PROMs.ResultsThe nine FGDs included 51 patients. In total, 27 domains and 92 subdomains were identified and then organized within the 7 broad categories of the WHOQOL framework. Patients in Singapore were more concerned about “financial resources, ” “work satisfaction” and “positive feelings” while less concerned about “freedom, physical safety and security” than patients in Western countries. “Home environment” and “work satisfaction” emerged as unique QoL domains relevant to patients with axial SpA (axSpA). PROMs for psoriatic arthritis (PsA) can capture both identified domains of PsA and axSpA.ConclusionsA wide range of QoL domains and subdomains are relevant to SpA patients in Singapore, and there appears to be minimal differences in their relative importance between SpA subtypes. This study supports the development and validation of common QoL‐specific PROMs for usage in SpA.