bluuebunny/crossref_metadata_2025_split huggingface dataset:
KLF7 Promotes Hepatocellular Carcinoma Progression Through Regulating SLC1A5‐Mediated Tryptophan Metabolism
Authors: Chai Bao , Zhang Anhong , Liu Yang , Zhang Xi , Kong Pengzhou , Zhang Zhuowei , Guo Yarong 
Published: December 2024

ABSTRACTKrüppel‐like factor 7 is a transcriptional activator and acts as an oncogene in human cancers, including hepatocellular carcinoma (HCC). Tryptophan metabolism is important for HCC cell proliferation, metastasis, and invasion. It is unclear whether KLF7 could regulate Trp metabolism in HCC. In this study, we found that Trp metabolism was suppressed in HCC cells with KLF7 knockdown. The mRNA and protein levels of SLC1A5, SLC7A5, and TPH1, as well as the content of Trp and serotonin, were reduced after KLF7 knockdown, and were potentiated following KLF7 overexpression. Increasing the content of serotonin could restore the malignancy of tumour cells in vitro and tumour growth in vivo. Conversely, decreasing the content of serotonin suppressed HCC cell proliferation. The binding activity of KLF7 was on the promoter of SLC1A5, and KLF7 positively regulated the expression of SLC1A5. KLF7 contributed to the proliferation and migration of HCC cells by up‐regulation of SLC1A5. Collectively, KLF7 promotes the progression of HCC through regulating Trp metabolism. The newly identified axis of KLF7/ SLC1A5 in HCC could represent a potential target for HCC therapy.
Effects of salinity stress on the growth performance, histological characteristics, and expression of genes related to apoptosis and immunity in channel catfish (Ictalurus punctatus)
Authors: Tang Luyu , Duan Yongqiang , Xie Bingjie , Liu Hongyan , Zhong Liqiang , Wang Minghua , Liu Ju , Su Chaofan , Chen Xiaohui , Zhang Shiyong 
Published: December 2024

AbstractSalinity is an important environmental factor affecting fish growth and development. To investigate the effects of salinity stress on the growth performance, tissue structures, and expression of genes related to apoptosis and immune response in large‐sized channel catfish (Ictalurus punctatus) juveniles, an 8‐week salinity stress experiment was conducted. Six salinity levels (3, 3.8, 4.7, 5.9, 7.3, and 9 psu) were set according to an equal logarithmic concentration gradient method, along with a control group (0), and growth performance and physicochemical indices were measured. The survival rate of channel catfish in all salinity groups was 100%. Body length, body weight, weight gain rate, and specific growth rate decreased with increasing salinity, with higher salinity levels resulting in more significant reductions in growth performance. At 9 psu, both the specific growth rate (SGR) and weight gain rate (WGR) decreased significantly to 0.61%/day and 40.86%, respectively (p < 0.05). Histological analysis results indicated that with the increase in salinity, the number of intestinal mucosal folds relatively increased, while the number of goblet cells gradually decreased. Hepatocytes became more densely packed, and the hepatic lobule gaps widened. Apoptosis detection results revealed that in the liver, the number of apoptotic cells at 4.7 psu salinity was more than that in the control group and at 9 psu salinity. In the intestine, the number of apoptotic cells at 9 psu salinity was significantly higher than in the other two groups (p < 0.05). Quantitative polymerase chain reaction (qPCR) analysis of the expression patterns of genes related to apoptosis and immunity showed that the expression levels of caspase 3, caspase 8, INF‐I, IL‐1β, and bax genes in the liver and intestinal tissues were higher in the experimental groups than in the control group, while the expression of bcl‐2 decreased with increasing salinity in liver tissue but increased in intestinal tissue. These findings can provide theoretical guidance for the aquaculture of channel catfish in saline‐alkali land.
Imitation of Location Choices for Foreign Investments: The Role of Subnational Foreign Locations' Cultural Tightness
Authors: Slangen Arjen H. L. , Valboni Riccardo , Braito Nazareno , Puck Jonas 
Published: December 2024

AbstractFirms are known to commonly imitate peers' foreign investment location choices. We shed further light on this phenomenon by exploring the role of foreign locations' cultural tightness, which refers to the prevalence of social norms in a location and the tolerance for deviance from them. Combining institutional theory with insights from research on cultural tightness, we hypothesize that firms are more strongly inclined to imitate peers' choice for a subnational foreign investment location when the location is culturally tighter. Our hypothesis receives consistent support in conditional logit analyses based on 2900 foreign investments in new manufacturing plants in US metropolitan areas over the period 2008–2019. Furthermore, the amplifying effect of a subnational location's cultural tightness on firms' propensity to imitate their peers' choice for the location seems to depend on firms' experience with cultural tightness and their home country's cultural distance from the USA. Our findings enrich international management research on location choice imitation, legitimacy risks, and cultural tightness.
Unveiling the Heterogeneity of Sensation Seeking and Collectivism Development in Chinese Adolescents
Authors: Chen Chuqi , Wang Xingke , Shen Tenghui , Tang Sai , Tao Sha , Wang Daoyang 
Published: December 2024

ABSTRACTObjectiveUnderstanding the impact of sociocultural tendencies on the personality development of adolescents represents a critical theoretical and practical issue in the field of adolescent development. In the context of China's collectivist culture, the developmental trajectories of and the interaction between sensation seeking and collectivism among adolescents remain largely unknown.MethodThis study examined the heterogeneity of the joint growth patterns of sensation seeking and collectivism and their interactions across distinct latent trajectory classes. We collected 3‐year longitudinal data from 20,225 Chinese adolescents (60.45% male).ResultsWe identified four unique joint developmental trajectories. Contrary to the traditional view that collectivism inherently suppresses sensation seeking, most adolescents (89.52%) exhibited synchronous growth of both dimensions. The development of adolescent sensation‐seeking behavior was significantly influenced by their alignment with societal contribution‐driven happiness and an unquestioning prioritization of collective interests.ConclusionsOur findings underscore the nuanced interplay and commonalities between sensation seeking and collectivism development among Chinese adolescents.
Unequal homework: The hidden forces of social class contexts and parental self‐efficacy in shaping educational outcomes
Authors: Mzidabi Johanne , Goudeau Sébastien , Delès Romain , Claes Nele , Easterbrook Matthew J. , Alexopoulos Theodore , Rouet Jean‐François 
Published: December 2024

AbstractThe Covid‐19 outbreak forced families and teachers to use digital technology to support students to engage in distance learning at home. According to their social class, families’ digital equipment, competences and uses vary markedly, which in turn, impacts children's academic achievement. Social class has also a great influence on cultural and parental practices at home, as well as on parental self‐efficacy regarding supporting children's academic achievement. The present study investigated whether, within a single model, structural factors, including home environment, cultural capital, and digital capital, contribute both directly and indirectly (via parental self‐efficacy) to the development of academic inequalities during homework. As predicted, analyses showed that families from working‐class backgrounds are less equipped and feel less competent in digital technology as compared to families from middle‐ and upper‐class backgrounds. Our findings also showed that families’ social class is a significant predictor of cultural capital and parental self‐efficacy which in turn contributes to educational inequalities in achievement. Future studies should delve deeper into the role of parental practices and their involvement, during homework, to educational inequalities.
Do external founder CEOs place strategic emphasis on innovation? An upper echelons perspective
Authors: Osses Lennart David , von Nitzsch Jannis , Engelen Andreas 
Published: December 2024

AbstractResearch compares the influence of two types of chief executive officers (CEOs) on a firm's innovation strategy: founder CEOs, who founded the firms they lead, and professional CEOs, who worked in corporations at different levels before being selected as CEOs. We introduce a third type of CEO, external founders, who founded other ventures before being appointed as CEOs. Drawing on upper echelons theory, we propose that the unique combination of external founder CEOs' values and knowledge predisposes them to place less strategic emphasis on innovation than founder CEOs do but more than professional CEOs do. Heterogeneity among external founder CEOs may be due to nuances related to their exposure to professional investors in and successful exits from the ventures they founded. We assess our hypotheses empirically using the innovation‐related speech in investor communications and patent applications of 1637 CEOs of 789 S&P 500 firms from 2000 to 2019. We find that external founder CEOs emphasize innovation less than founder CEOs do, but contrary to our hypotheses, also less than professional CEOs do. However, certain nuances in external founder CEOs' founding experience bring their strategic emphasis on innovation close to that of founder CEOs. We extend upper echelons research by providing a fine‐grained view of the role of (founding) experience and its qualitative nuances in shaping CEOs' strategic decision‐making.
Associations among chronotype and eating habits in adolescents are affected by study shift: A cross‐sectional study
Authors: Martins Raphael Corrêa , dos Santos Barbosa Brito Flávia , Curioni Cintia Chaves 
Published: December 2024

SummaryWe investigated the influence of chronotype on eating habits among adolescents attending schools with morning (07:00 hours–12:00 hours) or afternoon (13:00 hours–18:00 hours) shifts, hypothesizing that incompatibility of study schedules may be related to dietary choices. In this cross‐sectional study, 734 adolescents (aged 14–19 years) completed an online questionnaire covering eating habits, chronotype, sleep duration, social jet lag, socioeconomic data, physical activity and anthropometric measures. Odds ratios with 95% confidence intervals were estimated using adjusted logistic regression, stratified by study shift. In the morning shift, a morning chronotype was associated with higher odds of breakfast (odds ratio: 3.47; 95% confidence interval: 1.13–10.71) compared with an evening chronotype. Both morning and intermediate chronotypes were associated with higher odds of morning snack (odds ratio: 3.52; 95% confidence interval: 1.13–10.93; and odds ratio: 2.87; 95% confidence interval: 1.18–6.99) and lower odds of fast foods (odds ratio: 0.09; 95% confidence interval: 0.02–0.49; and odds ratio: 0.19; 95% confidence interval: 0.58–0.62). In the afternoon shift, a morning chronotype was associated with higher odds of breakfast (odds ratio: 5.22; 95% confidence interval: 1.85–14.72), beans (odds ratio: 3.57; 95% confidence interval: 1.19–10.74), vegetables (odds ratio: 3.52; 95% confidence interval: 1.28–9.69) and fruits (odds ratio: 4.50; 95% confidence interval: 1.55–13.07) compared with an evening chronotype. Intermediate chronotype was associated with higher odds of breakfast (odds ratio: 3.71; 95% confidence interval: 2.03–6.77), morning snacks (odds ratio: 2.45; 95% confidence interval: 1.09–5.50), vegetables (odds ratio: 1.92; 95% confidence interval: 1.03–3.58) and fruits (odds ratio: 2.50; 95% confidence interval: 1.27–4.89), and lower odds of high‐energy intake post‐dinner (odds ratio: 0.43; 95% confidence interval: 0.22–0.85). Adolescents with an evening chronotype had lower odds of having breakfast. Both chronotype and study shifts influenced specific food consumption habits.
Attitudes and Barriers to Patient Participation in Evidence‐Based Practice From Chinese Nurses' Perspectives: A Qualitative Content Analysis
Authors: Lai Jie , Brettle Alison , Zhang Yujie , Zhou Chunlan , Zhou Yanni , Li Chaixiu , Fu Jiaqi , Deng Shisi , Guo Zihan , Wu Yanni 
Published: December 2024

ABSTRACTPatient participation plays a vital role in evidence‐based practice (EBP), yet its development in clinical nursing is slow. Current research has focused on identifying barriers to patient participation in everyday care, with less research on barriers to patient participation in EBP. Therefore, a questionnaire containing basic information and open‐ended questions was used to explore nursing staff attitudes and barriers to patient participation in EBP. Responses to the open‐ended question were analyzed with content analysis. Four roles of patient participation, positive and negative attitudes toward patient participation, and 134 barriers to patient participation in EBP were extracted from 121 nursing staff responses through content analysis. Five categories of barriers were extracted from the 134 barriers to patient participation, including patient, cost‐effectiveness of EBP, healthcare staff, organization, and resource. This study found that patients' acceptance and trust in EBP also influenced their participation in the practices. Moreover, nursing staff have little knowledge of engaging patients in EBP. More educational strategies and organizational support should be provided to patients and nurses to promote patient participation.
Handling Distinct Correlated Effects with CCE
Authors: Stauskas Ovidijus , De Vos Ignace 
Published: December 2024

AbstractThe common correlated effects (CCE) approach by Pesaran is a popular method for estimating panel data models with interactive effects. Due to its simplicity, i.e., unobserved common factors are approximated with cross‐section averages of the observables, the estimator is highly flexible and lends itself to a wide range of applications. Despite such flexibility, however, the properties of CCE estimators are typically only examined under the restrictive assumption that all the observed variables load on the same set of factors, which ensures joint identification of the factor space. In this article, we take a different perspective, and explore the empirically relevant case where the dependent and explanatory variables are driven by distinct but correlated factors. Hence, we consider the case of Distinct Correlated Effects. Such settings can be argued to be relevant for practice, for instance in studies linking economic growth to climatic variables. In so doing, we consider panel dimensions such that as , which is known to induce an asymptotic bias for the pooled CCE estimator even under the usual common factor assumption. We subsequently develop a robust bootstrap‐based toolbox that enables asymptotically valid inference in both homogeneous and heterogeneous panels, without requiring knowledge about whether factors are distinct or common.
Latent subtypes of self‐injurious urges among adults engaging in disordered eating and non‐suicidal self‐injury
Authors: Moussaoui Jannah R. , Smith April R. , Velkoff Elizabeth A. 
Published: December 2024

AbstractBackgroundSelf‐injurious urges are arguably the clearest antecedents of engaging in self‐injurious behaviors (SIBs; e.g., binge eating, self‐induced vomiting, cutting, burning). However, self‐injurious urges demonstrate great heterogeneity, and it is unknown which are most closely linked to SIBs. This study aims to identify latent profiles of self‐injurious urges and subsequently examine associations between profiles and engagement in SIBs.MethodAdults (N = 124) who reported engaging in at least three SIBs in the past month completed six surveys a day assessing self‐injurious urges for 14 days (6600 responses). Latent profiles were constructed using within‐person intensity, variability, peak, duration, relative frequency, and overall stability of self‐injurious urges over the EMA period.ResultsFive distinct profiles were identified: “sustained,” “muted,” “sudden‐onset,” “volatile,” and “virtually absent.” SIB frequency differed across profiles, H(4) = 41.11, p < 0.001; η2 = 0.31, 95% CI [0.19, 0.48], and Dunn's post‐hocs indicated those in the “volatile” profile engaged in more SIBs than other profiles.ConclusionFindings support the presence of meaningful profiles of self‐injurious urges and suggest these profiles differ in levels of SIB engagement. Future work should prospectively examine associations between profile membership and engagement in SIBs and identify treatment targets to intervene on SIBs.
Conservation agriculture increases phosphorus pools and stock in the top 30 cm of soil: A three‐year study on a subtropical legume–rice rotation
Authors: Maniruzzaman  , Cheng Miaomiao , Islam Ariful , Kumar Utpol , Islam Jahedul , Nasreen Shah Shanjida , Haque Enamul , Akhter Sohela , Jahiruddin M. , Bell Richard , Jahangir M. M. R. 
Published: December 2024

AbstractThe adoption of conservation agriculture (CA) practices is likely to alter soil phosphorus (P) pools and availability leading to changes in P fertilizer use and management. However, the impacts of CA practices on soil P fractions and their distribution in the soil profile under rice‐based systems is not well‐understood. This study examined the effect of two crop establishment practices (strip planting, SP and conventional tillage, CT) and two crop residue levels (high residue, HR‐ 40% of above ground biomass and low residue, LR‐ 15%) on P fractions in the soil profile under a lentil–mungbean–rice sequence. After three consecutive years of CA practice, covering nine crops, composite soil samples were collected at 0–5, 5–15, 15–30, 30–45 and 45–60 cm depths and analysed for solution P, NaHCO3‐extracted inorganic (NaHCO3 Pi) and organic (NaHCO3Po) P, NaOH‐extracted inorganic (NaOH Pi) and organic (NaOH Po) P, stable P, residue P, total P, soil organic carbon (SOC) and total nitrogen (N). The inorganic P (solution P, NaHCO3 Pi, NaOH Pi and stable P) comprised 53–59% while the organic P (NaHCO3 Po and NaOH Po) comprised only 6%–13% of total P. However, CA practices increased SOC with the corresponding increase in soil organic P fractions. HR increased solution P, NaOH Po, stable P, residue P, total P, as well as SOC contents along with the stocks of total carbon (C), N, and P at up to 15 cm while increasing NaHCO3 Pi, NaOH Pi and TN at up to 30 cm depth compared with the LR. Likewise, SP increased the inorganic P fractions (NaHCO3 Pi and NaOH Pi) at 0–30 cm depth over the CT while P fractions in the deeper soil layers were similar to each other. In conclusion, the increase in soil P pools at up to 15–30 cm depths especially because of increased crop residue retention should allow for a decrease in P fertilizer inputs in intensive rice‐based systems.
Intercultural communication, world Englishes, and interculturality
Authors: Jenks Christopher J. 
Published: December 2024

AbstractIntercultural communication is a human encounter that is managed according to cultural systems, such as national identities. Although cultural systems permeate across time and space through all facets of life, intercultural communication research has a narrow empirical focus. That is, the work done by intercultural communication researchers is defined by its focus on interculturality. This interest in understanding interculturality is commensurate with world Englishes scholarship; that is, the latter field of study is committed to understanding the social and cultural dimensions of English. As the contributors of this special issue demonstrate, which includes an editorial introduction, a research bibliography, and 11 contributions from a diverse group of scholars looking at a range of contexts, such as Bahrain, South Africa, China, Turkey, and the Netherlands, the relationship between intercultural communication and world Englishes is helpful in understanding numerous empirical issues that are situated at the boundaries of language, communication, and society.
Intercultural communication: A research bibliography
Authors: Jenks Christopher J. 
Published: December 2024

AbstractThe research bibliography identifies key studies that contribute to the intercultural communication literature. The bibliography is divided into three publication categories: books, peer‐reviewed journal articles, and book chapters. Readers with an interest in intercultural issues, especially in relation to language and communication, will find this research bibliography particularly useful. The references included in the bibliography are especially helpful for readers new to intercultural communication research.
A Large‐Scale Serological Survey in Pets From October 2020 Through June 2021 in France Shows Significantly Higher Exposure to SARS‐CoV‐2 in Cats Compared to Dogs
Authors: Fritz Matthieu , Elguero Eric , Becquart Pierre , De Riols de Fonclare Daphné , Garcia Déborah , Beurlet Stephanie , Denolly Solène , Boson Bertrand , Rosolen Serge G. , Cosset François‐Loïc , Briend‐Marchal Alexandra , Legros Vincent , Leroy Eric M. 
Published: December 2024

ABSTRACTIntroductionSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has the potential to infect various animals, including domestic pets like dogs and cats. Many studies have documented infection in companion animals by molecular and serological methods. However, only a few have compared seroprevalence in cats and dogs from the general population, and these studies were limited by small sample sizes and collections over short periods. Our aim was to obtain a more accurate evaluation of seroprevalence in companion animals in France and to determine whether cats and dogs differ in their exposure to SARS‐CoV‐2.MethodsWe conducted an extensive serological survey of SARS‐CoV‐2, collecting blood samples from 2036 cats and 3577 dogs during routine veterinary medical examinations across different regions of metropolitan France from October 2020 to June 2021. This period encompassed the peaks and onset of two waves, as well as the emergence of the first variants. A microsphere immunoassay targeting the receptor‐binding domain and trimeric spike protein was used to detect anti‐SARS‐CoV‐2 antibodies. A subset of 308 seropositive samples was tested for the presence of neutralising antibodies.ResultsWe determined an overall seroprevalence of anti‐SARS‐CoV‐2 antibodies of 7.1% (95% confidence interval [CI]: 6.4%–7.8%) among the sampled pets. Cats exhibited a significantly higher seroprevalence (9.3%; 95% CI: 8.1%–10.1%) compared to dogs (5.9%; 95% CI: 5.2%–6.8%). Among the subset of seropositive samples, 81 (26.3%; 95% CI: 21.5%–31.6%) displayed neutralizing antibodies. Furthermore, seroprevalence in both species was lower in older animals and was not associated with sex. Finally, unlike cats, seroprevalence in dogs was found to be correlated with the date of sampling.ConclusionsThe large sample size enhances the reliability and statistical robustness of our estimates regarding pet exposure to SARS‐CoV‐2. This study on SARS‐CoV‐2 reaffirms the crucial importance of adopting a One Health approach incorporating domestic animals when managing an epidemic caused by a zoonotic virus.