bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers to intra-familial prevention of type 2 diabetes: A qualitative study on horizons of significance and social imaginaries
Authors: Grabowski Dan , Andersen Tue Helms 
Published: August 2018

Objectives In families living with type 2 diabetes, relatives have a significantly heightened risk of developing the disease. In many families, both the person with type 2 diabetes and his/her relatives lack detailed knowledge about this risk. One obstacle to constructive intra-familial prevention and risk reduction is the lack of perceived familial disease relevance. The objective of the present study is to explore barriers to prevention in families with at least one adult with type 2 diabetes. Methods Data were gathered during eight problem assessment and ideation workshops with families. The data were analyzed using radical hermeneutics and interpreted using Taylor’s concepts of social imaginaries and horizons of significance. Results The analysis revealed three main barriers: (1) Sole responsibilities and the absence of collective practices, (2) intra-familial differences in perceptions of risks and future health, and (3) lack of perceived disease significance and the ensuing lack of mutual care. The participating families all experienced one or more of the three identified primary barriers. Discussion The study has produced important knowledge about barriers to familial prevention of type 2 diabetes. The findings confirm that familial prevention is indeed a complex matter that calls for the use of complexity-oriented approaches in health care practice.
Unmet needs of family caregivers of hospitalized older adults preparing for discharge home
Authors: McCusker Jane , Yaffe Mark , Lambert Sylvie D , Cole Martin , de Raad Manon , Belzile Eric , Ciampi Antonio , Amir Ella , Hidalgo Marcela 
Published: August 2018

Objectives To describe unmet needs of caregivers of hospitalized older adults during the transition from hospital back home, and identify subgroups with different needs. Methods Patients and family caregivers were recruited from an acute care hospital in Montreal, Canada. Measures included Instrumental Activities of Daily Living (IADL), Hospital Anxiety and Depression Scale (HADS), Zarit burden scale, and Family Inventory of Needs. Dimensions of unmet needs were explored with principal component analysis; regression tree models were used to identify subgroups with different unmet needs. Results A total of 146 patient-caregiver dyads were recruited. Three categories of caregiver unmet needs were identified: patient medical information; role clarity and support; and reassurance. Caregiver subgroups with highest unmet needs were those with high burden of care plus depressive symptoms ( n = 46) and those caring for patients with low IADL scores ( n = 10). Discussion Caregivers with high burden and depression are those with the greatest unmet needs during the care transition.
Biomechanical testing of trans-humeral all-suture anchors for rotator cuff repair
Authors: Aramberri-Gutiérrez Mikel , Martínez-Menduiña Amaia , Boyle Simon , Valencia Maria 
Published: August 2018

Background Rotator cuff tears are one of the most common causes of shoulder pain. All-suture anchors are increasingly being used in the arthroscopic repair of rotator cuff tears. The purpose of this experimental study is to evaluate the biomechanical properties of all-suture anchors at different insertion sites in the proximal humerus relevant to rotator cuff repairs and the remplissage procedure. Methods Sixteen cadaveric shoulders were used for the study. Four all-suture anchors were inserted in each proximal humerus at common anchor insertion sites on the rotator cuff footprint and a simulated Hill–Sachs defect. Cyclic loading and load-to-failure tests were undertaken. The number of cycles, load to failure and nature of failure were recorded. Results The all-suture anchors placed in the cuff footprint using a transosseous technique displayed superior biomechanical properties. Sutures sited in this way demonstrated a maximum tensile load to failure of 542 N as well as a highest mean load to failure and the maximum number of cycles before anchor failure. In descending order, all-suture anchors placed in the lateral footprint were significantly superior to those located in the medial row and in a simulated Hill–Sachs defect. Discussion Anchors placed in the rotator cuff footprint exceeded the physiological isometric abduction forces for the supraspinatus and infraspinatus. Data obtained from our study suggest that all-suture anchors are strong enough to be used for the repair of rotator cuff tears.
Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial)
Authors: Hundscheid Tim , Onland Wes , van Overmeire Bart , Dijk Peter , van Kaam Anton H. L. C. , Dijkman Koen P. , Kooi Elisabeth M. W. , Villamor Eduardo , Kroon André A. , Visser Remco , Vijlbrief Daniel C. , de Tollenaer Susanne M. , Cools Filip , van Laere David , Johansson Anne-Britt , Hocq Catheline , Zecic Alexandra , Adang Eddy , Donders Rogier , de Vries Willem , van Heijst Arno F. J. , de Boode Willem P. 
Published: August 2018

AbstractBackgroundMuch controversy exists about the optimal management of a patent ductus arteriosus (PDA) in preterm infants, especially in those born at a gestational age (GA) less than 28 weeks. No causal relationship has been proven between a (haemodynamically significant) PDA and neonatal complications related to pulmonary hyperperfusion and/or systemic hypoperfusion. Although studies show conflicting results, a common understanding is that medical or surgical treatment of a PDA does not seem to reduce the risk of major neonatal morbidities and mortality. As the PDA might have closed spontaneously, treated children are potentially exposed to iatrogenic adverse effects. A conservative approach is gaining interest worldwide, although convincing evidence to support its use is lacking.MethodsThis multicentre, randomised, non-inferiority trial is conducted in neonatal intensive care units. The study population consists of preterm infants (GA < 28 weeks) with an echocardiographic-confirmed PDA with a transductal diameter > 1.5 mm. Early treatment (between 24 and 72 h postnatal age) with the cyclooxygenase inhibitor (COXi) ibuprofen (IBU) is compared with an expectative management (no intervention intended to close a PDA). The primary outcome is the composite of mortality, and/or necrotising enterocolitis (NEC) Bell stage ≥ IIa, and/or bronchopulmonary dysplasia (BPD) defined as the need for supplemental oxygen, all at a postmenstrual age (PMA) of 36 weeks. Secondary outcome parameters are short term sequelae of cardiovascular failure, comorbidity and adverse events assessed during hospitalization and long-term neurodevelopmental outcome assessed at a corrected age of 2 years. Consequences regarding health economics are evaluated by cost effectiveness analysis and budget impact analysis.DiscussionAs a conservative approach is gaining interest, we investigate whether in preterm infants, born at a GA less than 28 weeks, with a PDA an expectative management is non-inferior to early treatment with IBU regarding to the composite outcome of mortality and/or NEC and/or BPD at a PMA of 36 weeks.Trial registrationThis trial is registered with the Dutch Trial RegisterNTR5479(registered on 19 October 2015), the registry sponsored by the United States National Library of Medicine Clinicaltrials.govNCT02884219(registered May 2016) and the European Clinical Trials DatabaseEudraCT 2017–001376-28.
The effect of matrix cracking on mechanical properties in FRP laminates
Authors: Fikry M.J. Mohammad , Ogihara Shinji , Vinogradov Vladimir 
Published: August 2018

Abstract
Background
Fiber Reinforced Polymer (FRP) laminates have properties, which are highly dependent on the ply fiber orientations and which can be designed for optimum laminate performance. The purpose of this study is to investigate the effect of matrix cracking on the mechanical properties of FRP laminates with various off-axis angles, and to provide a critical test for an analytical solution using variational stress analysis.

Methods
Carbon and glass fiber reinforced polymer laminates (CFRP and GFRP) are tested. FRP prepregs are cured by using autoclave method to form laminates with layups [θm/ φn]s. The laminates are then loaded monotonically and cyclically to obtain their mechanical properties and the effect of matrix cracks on the properties. Some of the effects include reduction of laminates’ stiffness and residual strains after unloading. In order to obtain higher crack densities in specimens, artificial cracks method was introduced in this study, where notches were made at the edges of some specimens before tested in tension. Cracks observation for CFRP laminates is done by using the X-ray technique, while for GFRP laminates a DSLR camera is used.

Results
The measured stiffness reduction as a function of the crack density is compared to an analytical prediction for cracked angle-ply laminates based on a variational stress analysis. The experimental results for stiffness reduction agree well with the analytical results.

Conclusion
Understanding the behavior of damaged laminates with simple configurations, as performed in this study, is of high importance for prediction of damage effects on laminates with more complex configuration, e.g. with quasi-isotropic layups.
Vibrational biospectroscopic study and chemical structure analysis of unsaturated polyamides nanoparticles as antiâ€“cancer polymeric nanomedicines using synchrotron radiation
Authors: Heidari Alireza 
Published: August 2018

Firstly, unsaturated polyamides nanoparticles were hardened by continuous synchrotron radiation and then, the induced changes in its chemical structure were studied by Attenuated Total Reflectionâ€“Fourier Transform Infrared (ATRâ€“FTIR) spectroscopy. It was shown that applying synchrotron radiation for hardening not only leads to reduction of hardening time but also creates cross link in polymer by breaking Carbonâ€“Carbon double bond, without any considerable change in its chemical structure. In addition, an unsaturated polyamide nanoparticle as antiâ€“cancer polymeric nanomedicines is hardened by synchrotron radiation. Its chemical structure before and after hardening is studied using Raman and Attenuated Total Reflectionâ€“Fourier Transform Infrared (ATRâ€“FTIR) spectroscopy. The results show that Raman spectroscopy is considerably better than Attenuated Total Reflectionâ€“Fourier Transform Infrared (ATRâ€“FTIR) spectroscopy in detecting the changes happened in chemical structure.Â Â
Isolasi dan Identifikasi Bakteri Pelarut Fosfat dari Tanah Gambut
Authors: Larasati Ella Dewani , Rukmi MG Isworo , Kusdiyantini Endang , Ginting R Cinta Badia 
Published: August 2018

Phosphate (P) are macronutrients that necessary for growth and development of plants, But the availability of phosphate dissolved in the ground are very limited because trend is bound to minerals ground form phosphate complexs. One of the alternative to improve the efficiency of phosphate is by utilize phosphate solubilizing bacteria. Phosphate solubilizing bacteria is bacteria capable of dissolving phosphate that is not available become available, so that it can be absorbed by plants. Peat soils can be used as a source of phosphate solubilizing bacteria because , peat soils formed from litter and organic matter so, many microorganisms which live in peat soils one of them is a phosphate solubilizing bacteria. The aim of this research is to isolat, identify bacteria to species level using Biolog system GenIII Mircoplate, and test the ability of phosphate dissolution. The isolation is done with the methods spread plate in a media pikovkaya solid and testing the ability to isolat qualitatively glimpsed clear zone around colonies, measuring phosphate solubilizing index. testing the ability isolats quantitatively by measuring solubility phosphate using spektrofotometer, and identification isolats using Biolog System. Eighteen isolates phosphate solubilizing bacteria successfully obtained from of peat soils, two isolates of them potential in solubilizing phosphate, According to Biolog system the second isolates identified as Pseudomonas tolaasii (isolate PG2T.5) and a Bacillus pumilus (isolate PG3TT.2), each is about phosphate dissolved successive of 24,81 mg/L and 22,62 mg/L Key words: Peat Soil, Isolation, Phosphate Solubilizing Bacteria, Biolog System Identification
Kualitas Telur Puyuh Jepang (Coturnix coturnix japonica L.) berdasarkan Variabel pH telur, Indeks Kuning Telur (IKT) dan Indeks Putih Telur (IPT) setelah Penyimpanan yang Dilakukan Perendaman Pada Air Kapur Sebelum Penyimpanan
Authors: Djaelani Muhammad Anwar 
Published: August 2018

Puyuh Jepang (Coturnix coturnix japonica L.) banyak dibudidayakan untuk diambil telurnya karena produktivitas telur yang tinggi. Nilai gizi telur puyuh tidak kalah dengan telur unggas lain, sehingga dapat menambah variasi dalam penyediaan sumber protein hewani. Telur merupakan salah satu bahan makanan yang hampir sempurna. Bahan makanan ini mengandung zat gizi lengkap antara lain protein, lemak, vitamin dan mineral. Telur segar yaitu telur yang baru diletakkan oleh induk disarangnya, mempunyai daya simpan yang pendek. Salah satu faktor yang menyebabkan rusaknya telur adalah lama waktu penyimpanan . Penelitian ini bertujuan untuk menganalisis kualitas telur puyuh berdasarkan pH Telur, nilai Indeks Kuning Telur (IKT), Indeks Putih Telur (IPT) setelah perendaman dengan air kapur. Sampel yang digunakan adalah telur puyuh yang diambil pada hari kedua peneluran. Digunakan Rancangan acak lengkap dengan 5 kelompok perlakuan yaitu P1 kelompok telur,diamati pada hari ke 2. P2 kelompok telur disimpan dan diamati pada hari ke 16. P3 kelompok telur direndam pada air kapur selama 1 menit, disimpan dan diamati pada hari ke 16. P4 kelompok telur disimpan dan diamati pada hari ke 30. P5 kelompok telur direndam pada air kapur selama 1 menit, disimpan dan diamati pada hari ke 30. Data yang diperoleh dianalisis menggunakan ANOVA dengan taraf signifikansi 5%. Hasil penelitian menunjukkan semua variabel penelitian menenunjukkan penurunan seiring dengan bertambahnya waktu penyimpanan. Penurunan kualitas disebabkan faktor lamanya penyimpanan yang menyebabkan perubahan kondisi telur. Kata kunci : Penyimpanan telur, pH telur, Indeks Kuning Telur, Indeks Putih Telur
Pemanfaatan Bakteri Asam Laktat yang Di Isolasi Dari Saluran Pencernaan Ayam Lokal Untuk Pembuatan VCO Secara Fermentasi
Authors: Khotimah Husnul , Baniyah Laelatul , Hanafi Imam , Wardani Permadi Wisnu Aji , Sari Saskia Maisi Monika , Nur Jannah Siti 
Published: August 2018

Indonesia merupakan negara tropis yang memiliki banyak pulau dan merupakan negara produsen kelapa utama di dunia. .Pada tahun 2014 luas areal perkebuan tanaman kelapa di dunia mencapai 11 juta ha dan 93% berada di wilayah Asia Pasifik. Hal ini merupakan peluang untuk pengembangan kelapa menjadi aneka produk yang bermanfaat. Salah satu pemanfaatan kelapa dalam bidang kesehatan dalam upaya mendukung visi Indonesia sehat 2015 adalah dengan adanya VCO (virgin coconut oli). Proses pembuatan VCO adalah dengan cara fermentasi tidak mengalami proses pemanasan dan difermentasi dengan menggunakan bakteri asam laktat hasil dari isolasi pada saluran pencernaan ayam lokal, sehingga VCO yang dihasilkan memiliki kualitas yang baik. Berdasarkan uji fisik (uji viskositas) menunjukkan sampel H dengan isolat BUB 3 bahwa nilai viskositas sebesar 58,4325 Pa.s dan densitas 937,5 Kg/m3. Pada uji kimia (uji asam lemak bebas) didapatkan hasil kadar asam lemak bebas sampel H (BUB 3) dengan paling mendekati kadar asam lemak bebas menurut SNI 7381 tahun 2008 tentang VCO yaitu kadar asam lemak bebas maksimal dalam VCO adalah sebesar 0,2%. Sedangkan berdasarkan uji hasil pengujian organoleptik dari 11 koresponden didapatkan hasil bahwa tingkat kesukaan dari koresponden terhadap tekstur dari sampel VCO yaitu 7, yang berarti suka. Tingkat kesukaan terhadap aroma dari sampel VCO yaitu 7, yang berarti suka. Tingkat kesukaan terhadap rasa dari sampel VCO yaitu 5, yang berarti netral. Sedangkan tingkat kesukaan terhadap warna dari sampel VCO yaitu 5, yang berarti netral dan menunjukkan kualitas VCO yang didapatkan baik. Kata kunci: VCO, BAL, saluran pencernaan ayam, fermentasi
Pengaruh Kandungan Ekstrak Daun Zodia (Evodia suaveolens) Terhadap Mortalitas Larva Nyamuk Aedes aegypti
Authors: Basundari Sinta Anas , Tarwotjo Udi , Kusdiyantini Endang 
Published: August 2018

Aedes aegypti mosquito is a vector of dengue hemorrhagic fever (DHF). One place that is endemic by A.aegypti mosquitoes is the city of Semarang, specifically in Tembalang District. Tembalang district is one of the areas with highest DHF incidence rate. A.aegypti mosquito vector control is still using artificial insecticide, where the insecticide has negative impact to health and environment. Zodia leaves (Evodia suaveolens) are known to have potential as a natural insecticide, because they have secondary metabolites such as tannins, alkaloids, flavonoids that can be used as biolarvasides. This study aims to determine the content of phytochemical compounds of zodia leaves extract and to know the mortality in each population to zodia leaves extract. The extract of zodia leaf is obtained using maceration method. Chemical compounds contained in zodia leaves were analyzed using FT-IR. This research method is bioassay test, where the larvae are soaked with various series of concentration of zodia leaf extract. Each series of concentrations required ten larvae. The larvae used came from five kelurahan in Tembalang Subdistrict. The data were processed using probit analysis to obtain LC50. The results of LC50 obtained from the smallest to largest is 39,94 (34,67-45,28); 41,98 (36,6-48,07); 46,18 (39,28- 53,97); 47,62 (39,92-54,32) and 49,44 (42,24-58,25). The result of LC50 shows that is not significantly different, because there is the value of the overlapping fiducial limits between each population
Pengaruh Pemberian Hidrogen Peroksida (H2O2) Dalam Pengendalian Ektoparasit, Dan Kelangsungan Hidup Benih Ikan Nila Salin (Oreochromis niloticus) Di Balai Besar Perikanan Budidaya Air Payau Jepara
Authors: Arini Priesty Dyah , Muhammad Fuad , Baskoro Karyadi , Fahris Noor 
Published: August 2018

Nile tilapia fish (saline) is tolerable to high salinity and has a better resilience in environmental change, make it perfect for fish culture in the ponds. Problems which usually occur in fish culture is disease which is triggered by the decrease of water quality so that the parasytes begin to emerge. The ectoparasyte which usually attacks the fish is Trichodina sp. By adding hydrogen peroxide into the water medium, this type of ectoparasyte is expected to be controlled. This research is conducted to examine the influence of the hydrogen peroxide concentration difference to the increase of water medium quality, ectoparasyte controlling, and the survival rate of nile tilapia fish. The used method is by adding hydrogen peroxide into the water medium in various concentration, 0 ppm as control, 5 ppm, 10 ppm, and 15 ppm given in three times until day 10. The result of this research shown that different hydrogen peroxide concentration may influence the quality of the water medium, controling ectoparasyte, increase nile tilapia survival rate. The medium with hydrogen peroxide concentration (15 ppm) shows the best result. Keywords: nile tilapia fish, Trichodina sp, hydrogen peroxide, water medium quality, ectoparasyte control, survival rate.
Effects and Mechanisms of Jinniu Capsule on Methamphetamine-Induced Conditioned Place Preference in Rats
Authors: Shi Yu , Wang Feng , Hu A-Zhen , Wang Qing-Wen , Wu Jue-Lian , Li Ming-Hua , Cui Guang-Hui , Liu Li , Huang Si-Bin , Zhang Yu , Liu Han-Qing , Chen Yun 
Published: August 2018

Abstract
The aim of this study was to determine the effects of Jinniu Capsule on methamphetamine (METH)-induced conditioned place preference (CPP) in rats and identify the underlying mechanisms. An intraperitoneal injection of 3 mg/kg METH was used for CPP training in rats. The effects of Jinniu Capsule following a single dose on rat CPP and repeat dosing on METH withdrawal were evaluated. Western Blot analysis was used to measure protein expression of the PI3K-AKT-mTOR signaling pathway to determine the mechanisms of Jinniu Capsule. A single dose of Jinniu Capsule did not influence METH-induced CPP in rats. However, repeat dosing for 7 days significantly promoted METH withdrawal. Furthermore, METH withdrawal activated the PI3K-AKT-mTOR signaling pathway phosphorylation cascade, and Jinniu Capsule partly blocked this cascade. Jinniu Capsule demonstrated potential in promoting METH withdrawal in a rat CPP model, which may be related to its influence on the PI3K-AKT-mTOR signaling pathway.
Linguistic strategies for ad hoc categorization: theoretical assessment and cross-linguistic variation
Authors: Mauri Caterina , Sansò Andrea 
Published: August 2018

AbstractAd hoc categorization is the bottom-up abstraction of a category starting from concrete exemplars of the category itself. When we observe linguistic data, we find various phenomena that provide evidence for the ubiquity of such an on-line, goal-driven and context-dependent categorization in everyday communication. Beyond offering concept labels in the form of words, language indeed provides speakers with a great number of strategies to convey reference to a class by naming representative individuals. After providing a semantic and pragmatic account of ad hoc categorization in terms of indexicality, we will survey ad hoc categorization strategies in discourse and across languages: they can be syntactic (lists, general extenders, exemplifying constructions), morphological (heterogeneous plurals, collectives, aggregates, compounds), or in-between (reduplication). We will argue that all these strategies show a similar abstract structure consisting in a categorization trigger, that is, some prosodic, morphological or syntactic element triggering the abstractive inferential process towards the category identification, plus a linguistic expression referring to some overt category member, which is processed as the starting point for abstraction. The diachronic connections between these strategies and the pathways leading to their emergence and conventionalization also speak in favor of their unified treatment.
The role of exemplification in the construction of categories: the case of Japanese
Authors: Barotto Alessandra 
Published: August 2018

AbstractThe aim of this paper is to examine the role of exemplification in categorization processes, that is, how examples can be used in discourse to communicate conceptual categories. Based on data from present-day Japanese and a corpus-driven methodology, it will be shown that exemplifying constructions can be used 1) to refine already explicit categories by contextualizing and actualizing the reference, and 2) to create categoriesex novoby triggering associative inferences and abstractive processes. Accordingly, a detailed analysis of the linguistic properties of the examples will be provided in order to identify recurring encoding patterns and correlations with the functions described above. Furthermore, it will be argued that, although any conceptual category can be lexicalized by means of a category label, there exist some interesting correlations between the coding of the examples and the labelling of the category. Finally, we will conclude by showing that the linguistic analysis of exemplification can provide useful insights regarding the modalities in which the human brain categorizes.