bluuebunny/crossref_metadata_2025_split huggingface dataset:
National Comprehensive Cancer Network Infusion Efficiency Workgroup Study: Optimizing Patient Flow in Infusion Centers
Authors: Sugalski Jessica M. , Kubal Timothy , Mulkerin Daniel L. , Caires Rebecca L. , Moore Penny J. , Fiorarancio Fahy Rosanna , Gordon Jeanine N. , Augustyniak Connie Z. , Szymanski Gina M. , Olsen MiKaela , Frantz Diedra K. , Quinn Marisa A. , Kidd Sharol K. , Krause Diana M. , Carlson Robert W. , Stewart F. Marc 
Published: April 2019

PURPOSE: The National Comprehensive Cancer Network (NCCN) formed an Infusion Efficiency Workgroup to determine best practices for operating efficient and effective infusion centers. METHODS: The Workgroup conducted three surveys that were distributed to NCCN member institutions regarding average patient wait time, chemotherapy premixing practices, infusion chair use, and premedication protocols. To assess chair use, the Workgroup identified and defined five components of chair time. RESULTS: The average patient wait time in infusion centers ranged from 25 to 102 minutes (n = 23; mean, 58 minutes). Five of 26 cancer centers (19%) routinely mix chemotherapy drugs before patient arrival for patients meeting specified criteria. Total planned chair time for subsequent doses of the same drug regimens for the same diseases varied greatly among centers, as follows: Administration of doxorubicin and cyclophosphamide ranged from 85 to 240 minutes (n = 22); of FOLFIRINOX (folinic acid, fluorouracil, irinotecan hydrochloride, and oxaliplation) ranged from 270 to 420 minutes (n = 22); of rituximab ranged from 120 to 350 minutes (n = 21); of paclitaxel plus carboplatin ranged from 255 to 380 minutes (n = 21); and of zoledronic acid ranged from 30 to 150 minutes (n = 22) for planned total chair time. Cancer centers were found to use different premedication regimens with varying administration routes that ranged in administration times from zero to 60 minutes. CONCLUSION: There is a high degree of variation among cancer centers in regard to planned chair time for the same chemotherapy regimens, providing opportunities for improved efficiency, increased revenue, and more standardization across centers. The NCCN Workgroup demonstrates potential revenue impact and provides recommendations for cancer centers to move toward more efficient and more standard practices.
Intercellular transfer of P-glycoprotein mediates the formation of stable multidrug resistance in human bladder cancer BIU-87 cells
Authors: Cheng Xiao-zhi , Zhou Hui-liang , Tang Song-xi , Jiang Tao , Chen Qin , Gao Rui , Ding Yi-lang 
Published: April 2019

Background: To investigate the biological characteristics of acquired drug-resistant cells (AqMDRs) formed by intercellular P-glycoprotein (P-gp) transfer and whether AqMDRs can form stable drug-resistant strains.
Methods: Drug-sensitive BIU-87 cells were cocultured with doxorubicin(DOX)-resistant derivative BIU-87/DOX cells in Transwell chambers for up to 96 h. The presence of P-gp in recipient cell membranes (AqMDRs) was detected by confocal microscopy, CCK-8, Western blot, and RT-PCR were used to detect resistance index (RI), P-gp expression andMDR1 mRNA expression in AqMDRs after 0, 4, 8, 16, and 20passages and frozen/resuscitated 20th generation AqMDRs.
Results: There was an increase in P-gp transfer with longer coculture times of drug-resistant and sensitive strains. Without DOX, although the AqMDR numbers increased with each passage, the RI and P-gp expression decreased gradually, and the expression level of MDR1 mRNA did not change significantly. With DOX, the RI and P-gp expression increased slightly, and the MDR1 mRNA expression level gradually increased to the BIU-87/DOX level. AqMDRs can grow stably at drug concentrations slightly higher than the IC50 of sensitive strains, which sensitive strains cannot survive.
Conclusions: P-gp transfer between cells gradually increases with longer coculturing of drug-resistant and sensitive strains. The drug resistance of AqMDRs decreases without drug intervention, but with drug intervention, cells can maintain resistance and gradually develop into stable drug-resistant cells.
Psychological factors contributing to parenting styles: A systematic review
Authors: Vafaeenejad Zahra , Elyasi Fourozan , Moosazadeh Mahmood , Shahhosseini Zohreh 
Published: April 2019

Background: The set of strategies used by parents to put their children’s behaviors under control are called parenting styles, which can be influenced by numerous factors including socio-economic variables, cultural differences, personal characteristics, and psychological factors. These factors can differently contribute to parenting style. The purpose of this systematic review was to examine psychological factors affecting parenting style. Methods: This study was a comprehensive literature review using the keywords of parenting styles, psychological factors, and parenting to search the databases of Google Scholar, PubMed, Scopus, Web of , and Scientific Information Database. In this respect, 416 articles were extracted. 368 articles were removed after reviewing their abstracts and full text and eventually 48 articles were selected to elicit the required data. Results: Our findings were classified under two categories: factors related to parents (mental status, self-efficacy, parenting stress, perfectionism, personality traits, childhood trauma, marital satisfaction, parents’ attachment style, perceived parenting style, and substance abuse); and those related to children (child developmental and mental disability, child temperament, and anxiety). Conclusions: Considering the multiple psychological factors that affect parenting style, it is recommended to include an assessment of parent-child psychological status in family programs in order to identify the needs for -oriented care and take steps towards the development of parenting skills.
Voting Rules in Sequential Search by Committees: Theory and Experiments
Authors: Mak Vincent , Seale Darryl A. , Rapoport Amnon , Gisches Eyran J. 
Published: April 2019

We propose a committee extension of the individual sequential search model called the “secretary problem,” where collective decisions on when to stop the search are reached via a prespecified voting rule. We offer a game-theoretic analysis of our model and then report two experiments on three-person committees with either uncorrelated or perfectly correlated preferences under three different voting rules followed by a third experiment on single decision makers. Relative to equilibrium predictions, committees with uncorrelated preferences oversearched under minority and majority voting rules but, otherwise, undersearched or approximated equilibrium play. Individually, committee members were often less strategic when their preferences were uncorrelated than when they were perfectly correlated. Collectively, committees’ decisions were more strategic than single decision makers’ only under the unanimity rule, although still not significantly better in terms of the decision makers’ welfare. Finally, across our experiments that involved committee search, the unanimity rule always optimized committee welfare. This paper was accepted by Yan Chen, behavioral economics.
Das Management von Forschungsdaten als Handlungsfeld wissenschaftlicher Bibliotheken: Forschungsunterstützung am Beispiel ZB MED – Informationszentrum Lebenswissenschaften
Authors: Lindstädt Birte , Schmitz Jasmin 
Published: April 2019

ZusammenfassungDer Beitrag ordnet das Handlungsfeld Forschungsdatenmanagement zunächst in den Kontext sich wandelnder Anforderungen an wissenschaftliche Bibliotheken sowie wissenschaftspolitischer Strategien und Forderungen auf nationaler und europäischer Ebene ein. Im Anschluss liegt der Schwerpunkt auf einem möglichen Leistungsportfolio einer wissenschaftlichen Bibliothek, das Forschenden Unterstützung bei dem Management und der Publikation ihrer Forschungsdaten bietet. Die denkbaren Serviceleistungen reichen dabei von der Beratung bis hin zum Aufbau eigener Forschungsdateninfrastrukturen, die den Nachweis, die Bewertung, das Sichtbarmachen und die Überprüfung von Forschungsdaten ermöglichen.
Ein offener Wissensmarktplatz mit gesellschaftlicher Relevanz
Authors: Bonte Achim 
Published: April 2019

ZusammenfassungIn seiner Antrittsrede als Generaldirektor der Sächsischen Landesbibliothek – Staats- und Universitätsbibliothek Dresden, beschreibt Achim Bonte Bibliotheken im digitalen Zeitalter als offene, diversifizierte Lernräume, die wesentlich von der Vielfalt kreativer Mitarbeiter und den Ideen der Benutzer leben. Auf dieser Grundlage sieht er die SLUB als lebendigen Kommunikationsort und Infrastruktureinrichtung, die mit ihren digitalen und nicht-textuellen Angeboten sowie ihren Diensten entlang des Forschungskreislaufs gut gerüstet in die Zukunft blickt.
MusicSpace – Ein neues Konzept für Nutzungsbereiche wissenschaftlicher Musikbibliotheken
Authors: Haas Paul Tillmann 
Published: April 2019

ZusammenfassungDer Artikel stellt den MusicSpace als Variante des Makerspace vor. Unter Beachtung von Anforderungen an moderne Arbeits- und Lernorte werden Möglichkeiten zur Neuausrichtung der Nutzungsflächen wissenschaftlicher Musikbibliotheken beschrieben. Entsprechende Impulse ergeben sich aus den Tätigkeiten von Nutzern, die mit musikbezogenen Materialien arbeiten. Der MusicSpace des Bibliotheks- und Informationssystems der Universität Oldenburg dient hierbei als Beispiel.
On Küneth’s correlation and its applications
Authors: Mdzinarishvili Leonard 
Published: April 2019

Abstract
Let

𝒦

{\mathcal{K}}

be an abelian category that has enough injective objects,
let

T
:

𝒦
→
A

{T\colon\mathcal{K}\to A}

be any left exact covariant additive functor to an abelian category A and let

T

(
i
)

{T^{(i)}}

be a right derived functor,

u
≥
1

{u\geq 1}

, [S. Mardešić,
Strong Shape and Homology,
Springer Monogr. Math.,
Springer, Berlin, 2000].
If

T

(
i
)

=
0

{T^{(i)}=0}

for

i
≥
2

{i\geq 2}

and

T

(
i
)

⁢

C
n

=
0

{T^{(i)}C_{n}=0}

for all

n
∈
ℤ

{n\in\mathbb{Z}}

, then there is an exact sequence

0
⟶

T

(
1
)

⁢

H

n
+
1

⁢

(

C
*

)

⟶

H
n

⁢

(

T
⁢

C
*

)

⟶

T
⁢

H
n

⁢

(

C
*

)

⟶
0

,

0\longrightarrow T^{(1)}H_{n+1}(C_{*})\longrightarrow H_{n}(TC_{*})%
\longrightarrow TH_{n}(C_{*})\longrightarrow 0,

where

C
*

=

{

C
n

}

{C_{*}=\{C_{n}\}}

is a chain complex in the category

𝒦

{\mathcal{K}}

,

H
n

⁢

(

C
*

)

{H_{n}(C_{*})}

is the homology of the chain complex

C
*

{C_{*}}

,

T
⁢

C
*

{TC_{*}}

is a chain complex in the category A, and

H
n

⁢

(

T
⁢

C
*

)

{H_{n}(TC_{*})}

is the homology of the chain complex

T
⁢

C
*

{TC_{*}}

. This exact sequence is the well known Künneth’s correlation.
In the present paper Künneth’s correlation is generalized. Namely, the conditions are found under which the infinite exact sequence

⋯
⟶

T

(

2
⁢
i

+
1

)

⁢

H

n
+
i
+
1

⟶
⋯
⟶

T

(
3
)

⁢

H

n
+
2

⟶

T

(
1
)

⁢

H

n
+
1

⟶

H
n

⁢

(

T
⁢

C
*

)

\displaystyle\cdots\longrightarrow T^{(2i+1)}H_{n+i+1}\longrightarrow\cdots%
\longrightarrow T^{(3)}H_{n+2}\longrightarrow T^{(1)}H_{n+1}\longrightarrow H_%
{n}(TC_{*})

⟶

T
⁢

H
n

⁢

(

C
*

)

⟶

T

(
2
)

⁢

H

n
+
1

⟶

T

(
4
)

⁢

H

n
+
2

⟶
⋯
⟶

T

(

2
⁢
i

)

⁢

H

n
+
i

⟶
⋯

\displaystyle\longrightarrow TH_{n}(C_{*})\longrightarrow T^{(2)}H_{n+1}%
\longrightarrow T^{(4)}H_{n+2}\longrightarrow\cdots\longrightarrow T^{(2i)}H_{%
n+i}\longrightarrow\cdots

holds, where

T

(

2
⁢
i

+
1

)

⁢

H

n
+
i
+
1

=

T

(

2
⁢
i

+
1

)

⁢

H

n
+
i
+
1

⁢

(

C
*

)

{T^{(2i+1)}H_{n+i+1}=T^{(2i+1)}H_{n+i+1}(C_{*})}

,

T

(

2
⁢
i

)

⁢

H

n
+
i

=

T

(

2
⁢
i

)

⁢

H

n
+
i

⁢

(

C
*

)

{T^{(2i)}H_{n+i}=T^{(2i)}H_{n+i}(C_{*})}

.
The formula makes it possible to generalize Milnor’s formula for the cohomologies of an arbitrary complex, relatively to the Kolmogorov homology to the Alexandroff–Čech homology for a compact space, to a generative result of Massey for a local compact Hausdorff space X and a direct system

{
U
}

{\{U\}}

of open subsets U of X such that

U
¯

{\overline{U}}

is a compact subset of X.
Approximate Kernel-Based Conditional Independence Tests for Fast Non-Parametric Causal Discovery
Authors: Strobl Eric V. , Zhang Kun , Visweswaran Shyam 
Published: April 2019

Abstract
Constraint-based causal discovery (CCD) algorithms require fast and accurate conditional independence (CI) testing. The Kernel Conditional Independence Test (KCIT) is currently one of the most popular CI tests in the non-parametric setting, but many investigators cannot use KCIT with large datasets because the test scales at least quadratically with sample size. We therefore devise two relaxations called the Randomized Conditional Independence Test (RCIT) and the Randomized conditional Correlation Test (RCoT) which both approximate KCIT by utilizing random Fourier features. In practice, both of the proposed tests scale linearly with sample size and return accurate p-values much faster than KCIT in the large sample size context. CCD algorithms run with RCIT or RCoT also return graphs at least as accurate as the same algorithms run with KCIT but with large reductions in run time.
Modified Radon transform inversion using moments
Authors: Choi Hayoung , Ginting Victor , Jafari Farhad , Mnatsakanov Robert 
Published: April 2019

Abstract
Moment methods to reconstruct images from their Radon transforms are both natural and useful.
They can be used to suppress noise or other spurious effects and can lead to highly efficient reconstructions from relatively few projections.
We establish a modified Radon transform (MRT) via convolution with a mollifier and obtain its inversion formula.
The relationship of the moments of the Radon transform and the moments of its modified Radon transform is derived, and MRT data is used to provide a uniform approximation to the original density function.
The reconstruction algorithm is implemented, and a simple density function is reconstructed from moments of its modified Radon transform.
Numerical convergence of this reconstruction is shown to agree with the derived theoretical results.
Inverse source problems for the Korteweg–de Vries–Burgers equation with mixed boundary conditions
Authors: Montoya Cristhian 
Published: April 2019

Abstract
In this paper, we prove Lipschitz stability results for the inverse source problem of determining the spatially varying factor in a source term in the Korteweg–de Vries–Burgers (KdVB) equation with mixed boundary conditions.
More precisely, the Lipschitz stability property is obtained using observation data on an arbitrary fixed sub-domain over a time interval.
Secondly, we show that stability property can also be achieved from boundary measurements.
Our proofs relies on Carleman inequalities and the Bukhgeim–Klibanov method.
Photonic topological phase transition on demand
Authors: Kudyshev Zhaxylyk A. , Kildishev Alexander V. , Boltasseva Alexandra , Shalaev Vladimir M. 
Published: April 2019

Abstract
On-demand, switchable phase transitions between topologically nontrivial and trivial photonic states are demonstrated. Specifically, it is shown that the integration of a two-dimensional array of coupled ring resonators within a thermal heater array enables unparalleled control over topological protection of photonic modes. Importantly, auxiliary control over a spatial phase modulation opens up a way to guide topologically protected edge modes along generated virtual boundaries. The proposed approach can lead to practical realizations of topological phase transitions in many photonic applications, including topologically protected photonic memory/logic devices, robust optical modulators, and switches.
Differentiation of burial practices in the Corded Ware Culture. The example of the Magnice site in SW Poland
Authors: Baron Justyna , Furmanek Mirosław , Hałuszko Agata , Kufel-Diakowska Bernadeta 
Published: April 2019

Zusammenfassung
Der vorliegende Artikel befasst sich mit zwei gänzlich unterschiedlichen Bestattungsarten, die vom archäologischen Standpunkt der gleichen „Kultur“ angehören und höchstwahrscheinlich auch im Hinblick auf die Chronologie sehr vergleichbar sind. Die Unterschiede schließen sowohl Grabkonstruktionen als auch die Wahl der Grabbeigaben ein und sind ein Beweis für die Vielfalt der Ansätze im Bestattungsritual. Alle angesprochenen Gräber befinden sich auf dem zur Schnurkeramischen Kultur rechnenden Fundplatz Magnice im südwestlichen Polen. Der Beitrag richtet den Fokus u. a. auf Grabkonstruktionen, dem Zustand der entdeckten menschlichen Überreste und auf Gebrauchspuren beigegebener Steinartefakte.
Die Annahme der Verfasser ist, dass selbst kleine Lokalgruppen gültige Regeln der Bestattungspraktika erfahren, erlernt oder erspürt haben müssen. Obwohl das Konzept des „idealisierten Grabmodels“ sicherlich ein Teil der allgemein bekannten und geteilten kulturellen Regeln darstellte, zeigte die archäologisch nachgewiesene Praxis, dass diese auf unterschiedliche Weise umgesetzt wurde und dass die Umsetzungsphase auch die sozialen Verhandlungsmuster mit einbezog.
Der Papst und der Krieg
Authors: Koller Rotraud Becker/Alexander 
Published: April 2019

Riassunto
L’Istituto Storico Germanico di Roma ha concluso, nel 2016, l’edizione della quarta sezione della collana „Nuntiaturberichte aus Deutschland“, completando la pubblicazione della corrispondenza ufficiale tra i nunzi apostolici presso la corte imperiale e la Segreteria di Stato dal 1628 al 1635. Questo periodo va annoverato tra le fasi più complesse della Guerra dei Trent’anni. Grande spazio occupava all’inizio la successione mantovana e l’annesso conflitto che introdussero un teatro di guerra secondario, aperto sulla penisola, e toccarono necessariamente gli interessi del papa e della Curia. Intorno al 1630 predominavano poi, nell’Impero, il conflitto sull’editto di restituzione e la questione di Wallenstein. L’„internazionalizzazione“ della guerra trovò la sua prosecuzione con l’intervento della Svezia, alleata della Francia. A causa di questi avvenimenti i rapporti tra il papato da un lato e la Spagna e la corte imperiale dall’altro peggiorarono; di conseguenza s’incrinarono anche la reputazione e le possibilità d’azione della nunziatura viennese. Il punto più basso raggiunsero questi sviluppi con le proteste del cardinale Gaspare Borgia e la missione del cardinale Pázmány nel 1632. Un’importante accordo parziale per l’impero fu raggiunto nel 1635 con la Pace di Praga. Al contempo maturò in quegli anni presso le corti principesche europee la convinzione che una pace durevole sarebbe stata possibile solo in seguito a un congresso di pace generale e multilaterale. Le recenti pubblicazioni nel contesto della quarta sezione dei „Nuntiaturberichte“ permettono inoltre di rivalutare i documenti in esse riportati come fonti per la ricerca storica non solo nell’ambito di quesiti politici e confessioniali, ma anche nel campo della storia culturale moderna e dell’antropologia storica.
Die „Capitula de expeditione Corsicana“ Lothars I. vom Februar 825
Authors: Esders Stefan 
Published: April 2019

Riassunto
Il presente contributo analizza il capitolare emesso dall’imperatore Lotario I nella sua seconda visita in Italia, in occasione della quale procedette al reclutamento dell’esercito per una spedizione militare in Corsica. Dopo le analisi circa la tradizione del testo e la sua datazione (febbraio 825), viene indagata l’importanza della Corsica quale oggetto di ripetuti attacchi da parte dei Saraceni di Spagna e Nord Africa per ottenerne bottino, schiavi, nonché come base per incursioni sulla terraferma. L’emanazione del capitolare deve essere inserito all’interno di una serie di contemporanee relazioni diplomatiche intessute tra Costantinopoli, Bagdad, Roma e Aquisgrana in quel torno di anni. Il capitolare si rivolge in particolare ai conti di Toscana subordinati a Bonifacio II, conte di Lucca, il quale era stato incaricato come „praefectus Corsicae“ di proteggere l’isola e le coste della „Tuscia“. La parte centrale del contributo riguarda la ricostruzione del testo, che si presenta corrotto, e il commento delle decisioni emanate, con particolare attenzione al reclutamento dell’esercito da parte di vassalli regi e non e da parte degli uomini liberi. Lotario poté allora contare su uomini di grande esperienza come Wala; nelle sue disposizioni, egli adattò modelli longobardi e franchi che basavano il reclutamento sulla ricchezza e sulla proprietà (benefici, aggregazioni consortili di „liberi homines“), mentre concesse esenzioni, privilegiando alcuni amministratori di beni fiscali („gastaldi“) al servizio della corte, insieme ai loro vassalli. Sulla base delle misure adottate da Lotario poco dopo l’emanazione di questo capitolare per impedire il sottrarsi al reclutamento nell’esercito, viene infine esaminata l’efficacia di questo capitolare.
Fra’ Epifanio Fioravanti, Abenteurer und Agent zur Zeit des Dreißigjährigen Krieges
Authors: Becker Rotraud 
Published: April 2019

Riassunto
Il caso dell’eremita agostiniano Epifanio Fioravanti illustra un aspetto particolare della storia dei rapporti diplomatici nell’Europa dell’Età moderna. Esso è esemplicativo per il fenomeno, ben noto nel XVII secolo, che, accanto ai diplomatici ufficialmente incaricati, non raramente venivano investiti di missioni politiche anche membri degli ordini mendicanti. È evidente che tali mandati potevano oltrepassare largamente l’ambito delle trattative informali e della semplice redazione di relazioni, ma includessero potenzialmente anche operazioni segrete, e che vi ricorressero sia i sovrani secolari sia i rappresentanti altolocati della Curia romana. Le stesse nunziature apostoliche venivano coinvolte in rapporti di questo genere e dovevano temere per la loro credibilità.
Religion und religiöse Tradition: Unterscheidungsdiskurse zu den Grenzen des Islams
Authors: Dreßler Markus 
Published: April 2019

Zusammenfassung
Dieser Beitrag beschäftigt sich am Beispiel des islamischen Diskursfeldes mit der metasprachlichen Beschreibung objektsprachlicher Ab- und Ausgrenzungsdiskurse. Dies bringt zwangsläufig eine Auseinandersetzung mit den Dynamiken zwischen objekt- und metasprachlicher Begriffsebene mit sich. Der Artikel diskutiert in einem ersten Schritt Talal Asads Konzeption islamischer Orthodoxie und den ihr zugrundeliegenden Traditionsbegriff. In einem zweiten Schritt werden anhand von Beispielen aus dem nordamerikanischen Sufidiskurs und dem modernen türkischen Religionsdiskurs objektsprachliche Grenzziehungsdynamiken innerhalb des islamischen Diskursfeldes analysiert. Der letzte Teil des Aufsatzes widmet sich der Metaebene und führt, in Abgrenzung zum statischen Stammbaummodell, einen dynamischen Begriff von religiöser Tradition ein, der es ermöglichen soll, Überlagerungen zwischen religiösen Formationen niedrigen Verdichtungsgrades sowie Prozesse der Religionisierung ins Blickfeld zu nehmen.
„Umma – Be part of it!“
Authors: Maske Verena 
Published: April 2019

Zusammenfassung
Der vorliegende Beitrag analysiert die Bedeutung der Idee der umma in der „Muslimischen Jugend in Deutschland e. V.“ und der sie umgebenden pop-islamischen Szene entlang der Frage sozialer Grenzziehungsprozesse. Es soll gezeigt werden, dass soziale Grenzen nicht nur durch Zuschreibungs- und Exklusionsprozesse von außen konstruiert, sondern auch entlang von gemeinschaftsbildenden Identifikationsprozessen junger Musliminnen und Muslime hergestellt werden. Indem individuelle und kollektive Bedeutungen der Umma im Kontext des Untersuchungsfeldes erfasst werden, werden Prozesse der Vergemeinschaftung ebenso in den Blick genommen wie damit verbundene soziale Distinktionen, Exklusionen und Abwertungen. Dabei zeigt sich, dass soziale Grenzziehungsprozesse der pop-islamischen Szene sowohl gegenüber der deutschen Mehrheitsgesellschaft als auch gegenüber verschiedenen islamischen Strömungen je situations- und kontextabhängig ausgehandelt werden und sich als gleichzeitige Suche nach Partizipation und Abgrenzung bzw. Inklusion und Exklusion beschreiben lassen.