bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quand « sexe » et « sexualité » entrent en collision chez l'adolescente
Authors: Gueniche Karinne , Nataf Nicole , Yi Mi-Kyung 
Published: August 2019

Notre expérience clinique auprès de jeunes filles pubères qui viennent de subir un passage-à-l’acte sexuel et d’adolescentes qui présentent un syndrome de Mayer-Rokitansky-Kuster-Hauser (MRKH), confrontées à l’indication souvent précipitamment proposée et acceptée d’une intervention chirurgicale de construction vaginale, oblige à interroger la singularité de l’accès à la vie sexuelle féminine et du sexuel précoce : sa dimension traumatique, le conflit d’ambivalence du lien mère-fille et le risque dépressif associé et l’importance du facteur relationnel dans la construction de l’intériorité corporelle.
Du malaise dans la symbolisation à la reviviscence des ressources imaginatives
Authors: Katz-Gilbert Muriel 
Published: August 2019

Souvent présentée sous l’angle d’une crise, l’adolescence gagne à être pensée sous l’angle du malaise qui s’installe au cœur du processus de symbolisation (Roussillon et al ., 2007). Or, favoriser sa relance dans la prise en soins des adolescents présentant des pathologies de l’agir ne va pas de soi. L’auteure fait part d’un aménagement original du psychodrame psychanalytique : la médiation par la mythologie favorise le processus de la double-contenance : dans l’objet médiateur d’une part, et dans les cliniciens de l’autre (Lo Piccolo, 2015). Une vignette clinique permet d’illustrer la mise en place d’un dispositif qui favorise la relance du processus de symbolisation.
Retinoids Enhance the Expression of Cathelicidin Antimicrobial Peptide during Reactive Dermal Adipogenesis
Authors: Liggins Marc C. , Li Fengwu , Zhang Ling-juan , Dokoshi Tatsuya , Gallo Richard L. 
Published: August 2019

AbstractA subset of dermal fibroblasts undergo rapid differentiation into adipocytes in response to infection and acutely produce the cathelicidin antimicrobial peptide gene Camp. Vitamin A and other retinoids inhibit adipogenesis yet can show benefit to skin disorders, such as cystic acne, that are exacerbated by bacteria. We observed that retinoids potently increase and sustain the expression of Camp in preadipocytes undergoing adipogenesis despite inhibition of markers of adipogenesis, such as Adipoq, Fabp4, and Rstn. Retinoids increase cathelicidin in both mouse and human preadipocytes, but this enhancement of antimicrobial peptide expression did not occur in keratinocytes or a sebocyte cell line. Preadipocytes undergoing adipogenesis more effectively inhibited growth of Staphylococcus aureus when exposed to retinoic acid. Whole transcriptome analysis identified hypoxia-inducible factor 1-α (HIF-1α) as a mechanism through which retinoids mediate this response. These observations uncouple the lipid accumulation element of adipogenesis from the innate immune response and uncover a mechanism, to our knowledge previously unsuspected, that may explain therapeutic benefits of retinoids in some skin disorders.
DRAMATURGIA ENTRE SOM, SILENCIO E RUÍDOS
Authors: Diniz Elcio Levi Brandão 
Published: August 2019

O presente texto traz uma reflexão sobre o uso dos elementos do som em composições musicais e teatrais em que busca-se desestabilizar as hierarquias dos elementos da cena. Para melhor compreensão das articulações entre conceitos como Polifonia da Cena e Dramaturgia da Percepção, a pesquisa detém-se primeiramente nos apontamentos feitos por José Miguel Wisnik sobre o som, o silêncio e o ruído. Depois observa alguns tópicos do Serialismo e do Minimalismo buscando encontrar suporte para a análise de algumas obras de Heiner Goebbels.
A (des)judicialização da Educação Especial em Goiás
Authors: Tavares do Amaral Cláudia , Oliveira Ana Carla de 
Published: August 2019

Este artigo tem como objetivo analisar as decisões proferidas pelo Tribunal Justiça do Estado de Goiás no tocante ao acesso e permanência de educandos com deficiência, transtornos globais do desenvolvimento e altas habilidades ou superdotação na Educação Básica. Para compreensão do movimento de acesso ao judiciário para busca de direitos referentes à educação especial, a metodologia utilizada pautou-se na pesquisa documental e bibliográfica, a fim de empreender uma reflexão sobre a forma como o poder judiciário, ao longo do tempo interviu impondo sua decisão no cenário educacional. Tal análise foi norteada a partir das decisões judiciais já proferidas no estado de Goiás, no período de janeiro de 2015 a janeiro de 2016 e amparou-se, sobretudo, nos seguintes autores: Sahb (2003), Cury (2010) e Medeiros (2006). Os dados apontam para um movimento de (des)judicialização já que um número pequeno de ações foi encontrado. Observou-se também um redirecionamento para o Judiciário de resolução de situações referentes a questões administrativas e que pouco expressam a materialização de direitos.
Teores de elementos-traço em solos das margens do Rio Paraguai, Pantanal de Cáceres/Mato Grosso
Authors: Rocha Geilson Xavier , Pierangeli Maria Aparecida Pereira , Marques Mayara Cristina Santos 
Published: August 2019

A contaminação do solo por elementos-traço ​​ameaça ecossistemas e a saúde humana no mundo todo. Interferências antrópicas em ambientes naturais estão se tornando cada vez mais intensa aumentando os riscos de contaminação do solo. Estudos em ambientes naturais com diferentes tipos de solos e condições ambientais se fazem necessários para que se possa estabelecer valores orientadores da qualidade do solo para cada região, permitindo a identificação de áreas contaminadas e a avaliação dos riscos potenciais das atividades antrópicas sobre a contaminação do solo. Dessa forma, o objetivo deste trabalho foi determinar os teores de elementos-traço em solos de áreas de vegetação nativa as margens do rio Paraguai, Pantanal de Cáceres/MT. As amostras de solo foram coletadas na profundidade de 0,0 a 0,20 m, em doze áreas sob a presença das seguintes classes de solo: Argissolo, Gleissolo, Neossolo e Planossolo. A digestão das amostras baseou-se no método 3051-A, preconizado pela Agência de Proteção Ambiental dos Estados Unidos, sendo a determinação dos elementos efetuada por espectrometria de emissão atômica com plasma indutivamente acoplado (ICP-OES). Os teores médios (mg kg-1) dos elementos-traço foram: As (1,70); Ba (123,54); Cd (1,70); Co (5,37); Cr (36,66); Cu (41,60); Hg (8,26); Mo (0,25); Ni (9,47); Pb (7,45); Sb (32,18); Se (0,33) e Zn (26,26). Valores obtidos através do percentil 75, indicam que os teores de Ba (166,97 mg kg-1), Cd (2,19 mg kg-1), Hg (11,41 mg kg-1) e Sb (61,88 mg kg-1), encontram-se acima dos valores de prevenção – VP, preconizados pela Resolução 420/2009 do CONAMA. Entre os elementos-traço foi evidenciada estreita correlação entre o Ba e Cr (r = 0,92). Os teores de areia e argila determinados, apresentaram correlacão significativa (p ≤ 0,05) com os teores de Ba, Cd, Co, Cr, Cu, Ni, Pb e Zn, sendo que, a argila apresentou correlação positiva e a areia correlação negativa. O pH em H2O apresentou correlação significativa (p ≤ 0,05) apenas com o Se (r = 0,41). A CTC pH 7,0 apresentou correlação significativa com a maioria dos elementos-traços, sendo evidenciado uma estreita correlação com o Ba (r = 0,95). Tendo em vista que os teores verificados para Ba, Cd, Hg e Sb a partir do percentil 75 encontram-se acima do valor de prevenção estabelecido pela legislação nacional, torna-se necessário estipular valores de referências de qualidade para os solos do Pantanal, em busca de se estabelecer medidas de prevenção e preservação do solo e do ecossistema.
Composição e riqueza de peixes em diferentes corpos d’água no parque nacional das Araucárias, Sul do Brasil
Authors: Berto Jerri Andre , Ilha Criatiano , Souza-Franco Gilza Maria de 
Published: August 2019

O conhecimento das espécies de um determinado ambiente é base para futuros estudos ecológicos, bem como para o auxílio no manejo e conservação de áreas prioritárias. Para tal, esse estudo objetivou inventaria a composição de espécies de peixes em diferentes ambientes aquáticos no Parque Nacional das Araucárias (PNA), Santa Catarina. Foram avaliados 10 pontos amostrais com características distintas (riachos, lago de reservatório, açude e rios de maior porte) ao longo da área do Parque. Para a amostragem diferentes artes de pesca foram empregadas em cinco coletas com periodicidade trimestral. Um total de 1.022 exemplares foi registrado, distribuídos em 22 espécies, sete famílias e quatro ordens, das quais Siluriformes apresentou a maior riqueza para a área de estudo. Astyanax scabripinnis, Oligosarcus brevioris, Hoplias malabaricus e Rhamdia quelen apresentaram a maior amplitude de distribuição, enquanto as demais ficaram restritas a um ou poucos ambientes. Ainda, destaca-se a presença de Crenicichla empheres, espécie considerada endêmica do rio Chapecó, além de Cyprinus carpio, espécies exótica, que foi registrada em um açude no interior do Parque. Ademais, por meio da curva de acumulação, foi possível inferir que as maiores parcelas das espécies presentes na área do PNA foram registradas, haja vista a tendência da curva a atingir a assíntota. Por fim, destaca-se a ocorrência de Crenicichla lepidota, Pareiorhaphis vestigipinnis e Pareiorhaphis steindachneri, para as quais não havia ainda, registros para a bacia do rio Chapecó. Ressalta-se que a presença de algumas espécies possivelmente esteja associada a determinadas características estruturais e ambientais encontradas na área do Parque, reforçando a importância de tais áreas para a manutenção da biota, tal como os peixes.
Modest dose anti-thymocyte globulin administered intraoperatively is safe and effective in kidney transplantations: a retrospective study
Authors: Liu Hui-Ying , Cheng Yuan-Tso , Luo Hao Lun , Huang Chiang-Chi , Chen Chien Hsu , Shen Yuan-Chi , Lee Wen-Chin 
Published: August 2019

BackgroundAnti-thymocyte globulin (ATG) as induction therapy in renal transplantation is facing the dilemma of reducing the incidence of acute rejection (AR) and delayed graft function (DGF) or increasing risks of infection and malignancy. The purpose of this study was to delineate the safety and efficiency of the optimal ATG dosage.MethodsWe retrospectively evaluated 91 deceased donor kidney transplant recipients (KTRs) in our institution between March 2011 and January 2019. The patients were classified into three groups based on induction therapy: (1) Group 1: modest-dose ATG (three mg/kg) intraoperatively (N= 21); (2) Group 2: low-dose ATG (1–1.5 mg/kg) intraoperatively (N= 23); (3) Group 3: basiliximab 20 mg both on day 0 and 4 (N= 47). In Groups 1 and 2, all patients received a daily low-dose program (1–1.5 mg/kg each day) with target dosage of six mg/kg. Induction therapy was combined with standard immunosuppressive regimen consisting of calcineurin inhibitors, mycophenolate/the mammalian target of rapamycin inhibitors and corticosteroids.ResultsThere was no significant difference in patient characteristics among groups. The outcomes of infection rate, biopsy-proven acute rejection, post-transplant diabetes mellitus, graft survival, and patient survival were similar among groups. Compared to the daily low-dose ATG regimen, the intraoperative modest-dose regimen did not cause more dose interruption and hence was more likely to reach the target ATG dosage. The intraoperative modest-dose regimen also seemed to reduce the rate of DGF.DiscussionIn recent years, a trend of using a “lower” dose of ATG has seemed to emerge. Our results suggest intraoperative modest-dose ATG followed by daily low-dose ATG regimen was safe and effective in cadaveric renal transplantations for preventing DGF, AR, and graft loss.
Group B Streptococcus colonization induces Prevotella and Megasphaera abundance-featured vaginal microbiome compositional change in non-pregnant women
Authors: Mu Xiaofeng , Zhao Changying , Yang Junjie , Wei Xiaofang , Zhang Jiaming , Liang Cheng , Gai Zhongtao , Zhang Chunling , Zhu Dequan , Wang Ye , Zhang Lei 
Published: August 2019

Background
Previous studies have indicated that variations in the vaginal microbiome result in symptomatic conditions. Group B Streptococcus (GBS) is a significant neonatal pathogen and maternal vaginal colonization has been recognized as an important risk factor for neonatal disease. Therefore, it is important to discover the relationship between the composition of the vaginal microbiome and GBS colonization. This study explores the potential relationship between the composition of the vaginal microbiome and GBS colonization in non-pregnant Chinese women.

Methods
A total of 22 GBS-positive, non-pregnant women and 44 matched GBS-negative women were recruited for the current study. The composition of the vaginal microbiome was profiled by sequencing the 16S rRNA genes. The microbiome diversity and variation were then evaluated.

Results
The vaginal microbiome of the 66 subjects enrolled in the current study were compared and the results showed that GBS-positive women exhibited significant vaginal microbial differences compared with the GBS-negative women based on the analysis of similarities (r = 0.306, p < 0.01). The relative abundance of the bacterial genus Lactobacillus (p < 0.01) was significantly lower in the GBS-positive group, while the abundances of the bacterial genera Prevotella (p < 0.01), Megasphaera (p < 0.01), and Streptococcus (p < 0.01) were significantly higher in the GBS-positive group.

Discussion
The current study addressed significant variations across the communities of the vaginal microbiome in GBS-positive and GBS-negative women in a Chinese cohort, which paves the way for a larger cohort-based clinical validation study and the development of therapeutic probiotics in the future.
Risk and prognostic nomograms for hepatocellular carcinoma with newly-diagnosed pulmonary metastasis using SEER data
Authors: Ye Guanzhi , Wang Lin , Hu Zhengyang , Liang Jiaqi , Bian Yunyi , Zhan Cheng , Lin Zongwu 
Published: August 2019

Purpose
This research aimed to identify risk factors of pulmonary metastasis (PM) from hepatocellular carcinoma (HCC) and prognostic factors of patients with PM from HCC at initial diagnosis.

Methods
Patients diagnosed with HCC between 2010 and 2015 were reviewed retrospectively in the Surveillance, Epidemiology, and End Results (SEER) database. Patients with PM from HCC at initial diagnosis were identified from the entire cohort. Predictors for PM from HCC were identified by multivariate logistic regression analysis. Independent prognostic factors for patients with PM were determined by univariate and multivariate Cox regression analysis. Nomograms were also constructed for quantifying risk of metastasis and overall survival estimation visually.

Results
Our research included 30,641 patients diagnosed with HCC, of whom 1,732 cases were with PM from HCC at initial diagnosis. The risk factors causing PM from HCC were age (P = 0.001), race (P < 0.001), primary tumor size (P < 0.001), T stage (P < 0.001), N stage (P < 0.001), alpha-fetoprotein (P < 0.001), bone metastasis (P < 0.001), brain metastasis (P < 0.001), and intrahepatic metastasis (P < 0.001). The significantly prognostic factors for overall survival were age (P = 0.014), T stage (P = 0.009), surgical approach (P < 0.001), and chemotherapy (P < 0.001). Harrell’s C-index statistics of two nomograms were 0.768 and 0.687 respectively, indicating satisfactory predictive power.

Conclusions
This research provided evaluation of risk factors and prognosis for patients with PM from HCC. Two nomograms we developed can be convenient individualized tools to facilitate clinical decision-making.
Extraction and Characterization of Oil from Date Palm (Phoenix dactylifera) Seed
Authors: Olowokere J. A. , Onen A. I. , Odineze M. C. , B’aga I. D. , Kefas E. G. 
Published: August 2019

This work focuses on the extraction of oil from date palm seed. Using n-hexane in Soxlet extraction apparatus, standard procedures were followed to determine the oil feed stock yield. Proximate compositions and physicochemical characteristics were carried out. Also, Fourier Transform Infrared Spectroscopy (FTIR) and Gas Chromatography Mass Spectrometry (GC-MS) were used to determine the functional groups and the fatty acid composition of the oil respectively. The result shows that the appearance of date palm seed oil is reddish brown in colour. Result from the FTIR analysis also shows that 17 peaks were noticed from date palm seed oil, indicating the presence of various functional groups such as OH, C-H, C=C, C=O, C The dominating types and number of functional groups are found on the single bond stretch and on the fingerprint region skeletal vibration. Similarly, the GC-MS result also reveals that there are 5 dominating fatty acid compounds present in date palm seed oil in relation to their abundant relative weight composition. In date seed oil, oleic acid which comprise of omega-9 fatty acid is found to be the only monounsaturated fatty acid with the highest weight composition of 49.4%. The inference that can be drawn from the results in this work in relation to application suggest that, date palm seed oil will be suitable for soap production and cleansing agents. Also, omega-9 fatty acid has some health benefits that can strengthen the brain as well as the heart. Furthermore, research on the life shelf and storage of this oil should be looked into, as it relates to the peroxidation of oil.
The Impact of Tourism Development to Environmental and Socio Cultural Conditions of the People in the Taman Sari Tourism Area Yogyakarta
Authors: Hurdawaty Ramon , Kusumaningrum Dewi Ayu , Efferiandi Defri 
Published: August 2019

Aims: (1) To know the impact of tourism development on environmental conditions in the Taman Sari tourism area of ​​Yogyakarta, (2) To know the impact of tourism development on the socio-cultural conditions of the people in the Taman Sari tourism area in Yogyakarta.
Study Design: Case Study.
Place and Duration of Study: Taman Sari, Yogyakarta, Indonesia, Betweeen April Until June 2016.
Methodology: This research uses the method the qualitative study. While design research methodology used is a method case study. Data collection was conducted through in-depth interviews with related offices, manager of Taman Sari, visitor and community around Taman Sari Yogyakarta.
Results: (1) The positive impact of tourism development on environmental conditions is the level of public awareness and attention in waste management around the Taman Sari area in Yogyakarta, The negative impacts that are polluted water and air, damage to vegetation and wildlife ecosystems and damage to cultural heritage in the Taman Sari Yogyakarta tourism area, (2) The positive impact the tourism development about social and cultural namely Javanese gamelan, wayang kulit, ketoprak jawa and batik in the Taman Sari Yogyakarta tourism area and cultural acculturation also occurs in buildings and food around Taman Sari Yogyakarta tourist area. The negative impacts, namely a shift in culture among young people and upper middle class people with low taste in arts and culture, in line with the development of tourism in the Taman Sari area of ​​Yogyakarta, many foreign cultural are imitated by young people around the area Taman Sari Yogyakarta tours in particular how to dress and the culture of drinking alcoholic beverages.
Conclusion: There was an impact of positive and negative changes in the development of tourism on the environmental and socio-cultural conditions of the community around the Taman Sari area of Yogyakarta.
Center Conditions for a Class of Rigid Quintic Systems
Authors: Lu Fei Fei 
Published: August 2019

The problem of determining necessary and sufficient conditions on P and Q for system.
x = - y+P(x+y),y = x+Q(x+y) to have a center at the origin is known as the Poincaré center-focus problem. So far, people has tried many ways to solve the problem of central focus. However, it is difficult to solve the center focus problem of higher order polynomial system. In this paper, we use the Poincaré and Alwash-Lloyd methods to study the center focus problem and derive the center conditions of the five periodic differential equation.
Comparison of Anxiolytic Effect of Aqueous Extract of Root of Valeriana officinalis with Buspirone in Mature Male Mice
Authors: Gordan Atefe , Taheri Elham , Saeidi Jafar 
Published: August 2019

Background: Anxiety is the most common psychiatric disorder which can be cured by herbal and chemical medicine. Herbal medicine and complementary medicine are widely used among people suffering from anxiety disorder. Valeriana officinalis known to cause anxiolytic and sedative effects to have a special place in traditional Chinese, Indian and Iranian medicine.
Aims: This study aims to compare the anxiolytic effect of aqueous extract of root of V. officinalis root with Buspirone in mature male mice.
Study Design: Study was conducted in the Islamic Azad University of Mashhad to an animal room of the Faculty of Basic Sciences, Azad University of Nishabur, under standard conditions. This experimental study has been demonstrated by control and experimental groups. The sample consisted of 30 mature male mice assigned into five groups of six: group A receiving distilled water (control group), group B, group C and group D receiving 100 mg/kg, 200 mg/kg and 300 mg/kg aqueous extract of V. officinalis, respectively, and group E receiving 30 mg/kg buspirone orally in drinking water. Anxiolytic effects were evaluated 10 days after receiving by using maze. One-way ANOVA and T-test were analyzed by using SPSS 19 software package.
Results and Discussion: The results show that the aqueous extract of V. officinalis root causes a significant increase in the number of arrivals and elapsed time in open arms compared to Buspirone. Medicinal plants currently form an important part of traditional medicine in many countries and they have a special place in new therapeutic approaches. ANOVA and T-test results showed a significant (P<0.05) relationship between the anxiolytic effect of aqueous extract of V. officinalis root and Buspirone in mice.
Conclusion: It can be concluded that V. officinalis are more effective in reducing anxiety compared to buspirone.
Child‐related attributions of hostile intent and harsh discipline: Moderating effects of anger
Authors: Milner Joel S. , Wagner Michael F. , Crouch Julie L. , McCarthy Randy J. 
Published: August 2019

AbstractTwo studies tested whether attributions of hostile intent (AHI) and anger for ambiguous child behaviors uniquely predict parents’ harsh verbal discipline (HVD) and harsh physical discipline (HPD) or whether AHI only predicts harsh discipline when AHI occurs in conjunction with anger, as suggested by the Integrated Cognitive Model of general aggression (Wilkowski & Robinson, 2010, J. Pers., 78, 9–38). Replicating previous studies, the expected positive bivariate relationships between AHI, anger, HVD, and HPD were found in Study 1 (N = 493). However, when AHI, anger, and the AHI by anger interaction were considered simultaneously, patterns of prediction varied by discipline type. For HVD, high levels of AHI, high levels of anger, and the AHI by anger interaction (at high levels of AHI and anger) each were significant predictors. For HPD, low levels of AHI, high levels of anger, and the AHI by anger interaction (at high levels of AHI and anger) were significant predictors, suggesting a possible suppressor effect for AHI. These results were replicated in Study 2 (N = 503). Thus, there was support for the contention that AHI only predicts harsh discipline when AHI occurs in conjunction with anger with respect to HPD but this was not the case for HVD. Since AHI suppressor effects were observed for HPD in two large sample studies, variables that may account for the AHI suppressor effects and the need for testing more complex interactive predictive models of harsh parenting behaviors are discussed.