bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient-related factors that link chronic kidney disease and periodontitis: a scoping review
Authors: Bunte Kübra , Brunet-Llobet Lluís , Rocha-Eiroa María Dolores , Ramírez-Rámiz Albert , Mahmoud Muhiddin Abdi , Mashala Elias Isaack , Miranda-Rius Jaume 
Published: December 2024

AbstractSeveral studies have proposed the existence of an association between periodontitis and chronic kidney disease (CKD) based on biological premises. There is growing evidence that chronic inflammation caused by periodontitis may contribute to the progression of CKD. The present study aimed to investigate studies that link CKD and periodontitis, including periodontitis proxies such as oral hygiene and tooth loss, and patient-related factors such as inflammatory response and genetic polymorphisms. An electronic search was conducted on the MEDLINE (Pubmed), Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, and Web of Science databases using an advanced search option up until August 2024. Thirty-two studies were included: 4 interventional, 16 cohort, and 12 case–control. Overall, the prevalence of periodontitis was significantly higher in patients with CKD: the diagnosis of periodontal disease was associated with an increase in the risk of incident CKD, and parameters of periodontal disease were negatively correlated with kidney function. Inside the field of periodontal medicine, the current evidence indicates a possible association between CKD and periodontitis and supports future longitudinal studies to investigate the two-way relationship between the diseases and their pathophysiology, and possibly to establish cause and effect.
Bi-accessible and Bipresentable 2-Categories
Authors: Di Liberti Ivan , Osmond Axel 
Published: December 2024

Abstract
We develop a 2-dimensional version of accessibility and presentability compatible with the formalism of flat pseudofunctors. First we give prerequisites on the different notions of 2-dimensional colimits, filteredness and cofinality; in particular we show that

$$\sigma $$

σ

-filteredness and bifilteredness are actually equivalent in practice for our purposes. Then, we define bi-accessible and bipresentable 2-categories in terms of bicompact objects and bifiltered bicolimits. We then characterize them as categories of flat pseudofunctors. We also prove a bi-accessible right bi-adjoint functor theorem and deduce a 2-dimensional Gabriel-Ulmer duality relating small bilex 2-categories and finitely bipresentable 2-categories. Finally, we show that 2-categories of pseudo-algebras of finitary 2-monads on

$$\textbf{Cat}$$

Cat

are finitely bipresentable, which in particular captures the case of

$$\textbf{Lex}$$

Lex

, the 2-category of small lex categories. Invoking the technology of lex-colimits, we prove further that several 2-categories arising in categorical logic (Reg, Ex, Coh, Ext, Adh, Pretop) are also finitely bipresentable.
Receipt of guideline-concordant care and survival among young adult women with non-metastatic breast cancer
Authors: Bhattacharya Manami , Liu Benmei , Kurian Allison W. , Stevens Jennifer , Enewold Lindsey , Penn Dolly C. 
Published: December 2024

Abstract
Purpose
Adolescent and young adults (AYA) with breast cancer, compared to older adults, are diagnosed with more aggressive cancers, at more advanced stages and may undergo more aggressive treatment but have worse survival. Despite this, no research has studied the effects of the receipt of National Comprehensive Cancer Network (NCCN) defined guideline-concordant care (GCC) for breast cancer on AYA survival. We examined the association of GCC with survival among young adult (20–39 years old) breast cancer survivors.

Methods
We used the Patterns of Care Study; a stratified random sample of 952 young adult women diagnosed with Stage I–III breast cancer in 2013. NCCN guidelines were used to categorize treatment as GCC or non-GCC. We used Kaplan–Meier curves, log-rank tests, and Cox-proportional hazards models to evaluate the effect of GCC on breast cancer-specific survival, stratifying by triple-negative breast cancer (TNBC) and non-TNBC, and adjusting for sociodemographic and clinical factors.

Results
All univariate analyses showed that non-GCC was associated with worse survival than GCC. The association was statistically significant for non-TNBC (Hazard ratio: 3.45, CI 1.64–7.29) and TNBC (Hazard ratio: 3.70, CI 1.02–13.43) in multivariable Cox models adjusted for sociodemographic variables and for non-TNBC (Hazard ratio: 3.13, CI 1.13–8.72) when the model was adjusted for sociodemographic and clinical variables.

Conclusion
Among young adult women with non-metastatic breast cancer, while receipt of NCCN GCC is univariately associated with better survival for both TNBC and non-TNBC, the effect of sociodemographic and clinical factors on the association differs by TNBC status. Further investigation with larger TNBC samples is needed.
A comparison of representations in grammar-guided genetic programming in the context of glucose prediction in people with diabetes
Authors: Ingelse Leon , Hidalgo J. Ignacio , Colmenar J. Manuel , Lourenço Nuno , Fonseca Alcides 
Published: December 2024

AbstractThe representation of individuals in Genetic Programming (GP) has a large impact on the evolutionary process. In previous work, we investigated the evolutionary process of three Grammar-Guided GP (GGGP) methods, Context-Free Grammars GP (CFG-GP), Grammatical Evolution (GE) and Structured Grammatical Evolution (SGE), in the context of the complex, real-world problem of predicting the glucose level of people with diabetes two hours ahead of time. We concluded that representation choice is more impactful with a higher maximum depth, and that CFG-GP better explores the search space for deeper trees, achieving better results. Furthermore, we find that CFG-GP relies more on feature construction, whereas GE and SGE rely more on feature selection. Additionally, we altered the GGGP methods in two ways: using $$\epsilon$$
ϵ
-lexicase selection, which solved the overfitting problem of CFG-GP and helps it to adapt to patients with high glucose variability; and with a penalization of complex trees, to create more interpretable trees. Combining $$\epsilon$$
ϵ
-lexicase selection with CFG-GP performed best. In this work, we extend on the previous work and evaluated the impact of initialization methods in the quality of solutions. We found that they have no significant impact, even when the change of representation has.
Synthesis and characterization of magnetically-active nickel-yttrium oxide (Ni-Y2O3) nanocomposite particles prepared with modified ultrasound spray pyrolysis device
Authors: Krajewski Marcin , Rudolf Rebeka , Švarc Tilen , Majerič Peter , Sobczak Kamil , Lewińska Sabina , Osial Magdalena , Tokarczyk Mateusz 
Published: December 2024

AbstractThe synthesis of magnetically-active nickel-yttrium oxide (Ni-Y2O3) nanocomposite particles is described in this work. The investigated material is produced with a modified ultrasound spray pyrolysis (USP) device which differs from a common USP setup in terms of use of three independently heating zones. They provide a direct feed of H2 to the second reaction zone and allow controlling the formation of the nanocomposite particles and facilitating their post-reaction stabilization with polyvinylpyrrolidone (PVP). According to the morphological and structural studies, the Ni-Y2O3 material takes a form of nanoparticles whose sizes are not homogeneously distributed as well as shapes are not smooth due to the successful formation of composite material with two interpenetrating phases. Moreover, the organic layer is detected on the surface of the nanoparticles which confirms the presence of PVP stabilizer. The magnetic investigations confirm that the Ni-Y2O3 nanocomposite reveals a spin glass-like behavior in which a collective freezing of magnetic moments might occur due to the interparticle interactions between Ni nanocrystallites presented in the sample.
Interference effects in differential cross sections for two-electron transfer
Authors: Belkić Dževad 
Published: December 2024

AbstractDifferential cross sections for simultaneous capture of both electrons by alpha particles from helium targets are computed. Employed are several quantum-mechanical distorted wave four-body methods of first- and second-orders. The main focus is on the cross section sensitivity as a function of different perturbation interactions and scattering states. Two aspects are considered. One is for theories with the same perturbation interactions and different scattering states. The other is for theories with the same scattering states and different perturbation interactions. In this context, the interference effect on two levels is examined. One compares the yields from the internuclear potential and the interactions between nuclei and two electrons. The other contrasts the contributions from the channel states with and without the distorted waves generated by the relative motions of nuclei. Depending on the employed theory, differential cross sections can be strongly or mildly influenced by the variability in all the mentioned frameworks. The salient illustrations are reported at intermediate energies 180-900 keV for which the experimental data are available. It is found that the second-order theories are in much better agreement with the measured cross sections than the first-order theories.
Pharmacist-led interventions at hospital discharge: a scoping review of studies demonstrating reduced readmission rates
Authors: Weber Carole , Meyer-Massetti Carla , Schönenberger Nicole 
Published: December 2024

Abstract

Background
Substantial numbers of hospital readmissions occur due to medication-related problems. Pharmacists can implement different interventions at hospital discharge that aim to reduce those readmissions. It is unclear which pharmacist-led interventions at hospital discharge are the most promising in reducing readmissions.

Aim
This scoping review aimed to summarise pharmacist-led interventions conducted at hospital discharge that demonstrated a reduction in readmissions.

Method
We searched the MEDLINE, EMBASE and CINAHL databases up to February 2024. We included studies that focused on pharmacist-led interventions at hospital discharge and reported significant readmission reductions. Two reviewers independently screened titles, abstracts and full texts. Data extracted included study characteristics, populations and the type of implemented pharmacist-led interventions along with the reduction in readmission rates achieved.

Results
We included 25 articles for data synthesis. Many of the studies included either implemented at least two interventions concurrently or were part of broader programmes involving other healthcare professionals. The most common pharmacist-led interventions associated with reduced readmission rates included medication reconciliation, counselling and post-discharge follow-up by telephone. Follow-up primarily aimed to improve patients’ treatment adherence through education about their medications. Furthermore, many studies reported on multi-component interventions that began at hospital admission or during inpatient stays, not only at discharge.

Conclusion
Successfully reducing readmissions through pharmacist-led interventions at hospital discharge suggests the effectiveness of a holistic approach incorporating multiple interventions. While these findings offer insights for pharmacists, further research should focus on conducting high-quality studies using a multifaceted approach to identify the most appropriate timing and combination.
Willful ignorance in law and epistemology
Authors: Bnefsi Sayid R. 
Published: December 2024

Abstract
In analytic epistemology, the propositional ignorance of an agent is consistently defined in terms of an agent not having knowledge or true belief that something is the case. Recently, however, Piedrahita (2021) and Pritchard (2021) have argued that ignorance involves some kind of epistemic fault. Pritchard claims that ignorance is the product of an intellectual defect in the agent as an inquirer, whereas Piedrahita claims that ignorance involves an agent being in a certain kind of epistemically suboptimal position. This article uses willful ignorance in Anglo-American criminal law as a lens through which to assess these claims. First, I argue that willful ignorance is a counterexample to Piedrahita’s view of ignorance. Second, I argue that Pritchard’s view of ignorance illuminates the epistemic culpability of willful ignorance, but the view faces challenging questions about the relationship between epistemic norms and epistemic values.
Racial variations in maxillomandibular advancement for obstructive sleep apnea: a systematic review and meta-analysis
Authors: Nanu Douglas P , Diemer Tanner J. , Nguyen Shaun A. , Tremont Timothy , Meyer Ted A. , Abdelwahab Mohamed 
Published: December 2024

Abstract
Purpose
We aimed to explore alterations in polysomnographic, cephalometric, and subjective outcomes amongst different ethnic/racial groups after MMA for OSA.

Methods
A meta-analysis was performed according to PRISMA reporting guidelines. The COCHRANE Library, CINAHL, PubMed, and Scopus were searched from inception to August 8, 2023. Each measure was weighted according to the number of patients affected. Heterogeneity among studies was assessed using χ2 and I2 statistics with fixed effects (I2 < 50%) and random effects (I2 ≥ 50%).

Results
Twenty studies with a total of 469 patients (n = 257 Caucasians, n = 204 Asians, n = 8 Latinos) with a mean patient age of 40.0 years (range: 18–67; 95% CI: 38.0, 42.1). The mean difference for Caucasians were AHI: -39.6 (95% CI: -55.0, -24.1; p <.001), LSAT: 7.5 (95% CI: 5.7, 9.3; p <.0001), and ESS: -4.5 (95% CI: -5.6, -3.4; p <.0001). The mean difference for Asians were AHI: -42.7 (95% CI -49.3, -36.0; p <.0001), LSAT: 13.8 (95% CI: 10.0, 17.4; p <.0001), and ESS: -6.7 (95% CI: -9.9, -3.5; p <.0001). The mean difference for Latinos were AHI: -21.2 (95 CI%: -37.7, -4.6; p =.01), and ESS: -2.0 (-7.9, 3.9; p =.50). Greater reduction of AHI was seen in Asians vs. Caucasians and Asians vs. Latinos. Lastly, the reduction of ESS was significantly better for Asians vs. Caucasians.

Conclusion
The study highlights significant variations in MMA outcomes among different ethnic/racial groups. Asians tend to have more severe OSA preoperatively and experience greater postoperative improvements in AHI, LSAT, and ESS compared to Caucasians.
Strategic initiatives to address greenwashing
Authors: Buttigieg Christopher P. , Pulis Sarah 
Published: December 2024

Abstract
This article examines the December 2023 report by the International Organisation of Securities Commissions (IOSCO) titled “Supervisory Practices to Address Greenwashing,” alongside the European Union’s regulatory framework aimed at curbing greenwashing in sustainable finance disclosures. Greenwashing—defined as the misrepresentation of sustainability credentials to attract investors—poses significant threats to investor protection and market integrity, potentially leading to a loss of trust in financial providers. Despite efforts by IOSCO and the EU to improve transparency, the persistence of greenwashing is fueled by fragmented regulations, complex disclosure requirements, and the rapid growth of Environmental, Social, and Governance (ESG) investing. This article argues for greater international harmonization, proportionate regulation, and effective enforcement of oversight mechanisms to preserve the credibility of sustainable finance. It highlights the crucial role of global cooperation and national initiatives, specifically those by the Malta Financial Services Authority (MFSA), in addressing these challenges. Structured into four sections—covering the role of IOSCO in the ESG regulatory landscape, EU initiatives for sustainable finance, supervision and enforcement against greenwashing, and MFSA’s local efforts—the article provides a comprehensive review of current ESG investment practices and the ongoing struggle for enhanced transparency and accountability in financial markets.
Experiences of Acculturation Stress in First-Generation Immigrant Children: Examining the Relationship Among Acculturation Stress, Depression, and Family Dynamics
Authors: Allen Myles , Armenta Belinda , Watters Elizabeth R. , Aflatooni Laleh , Sorenson Laurie 
Published: December 2024

AbstractThroughout the years, immigration has been a significant movement in the USA and leads to the examination of acculturative stress. By employing the acculturation stress and vulnerability models, the present study aimed to examine the association among acculturation stress, self-esteem, depression, family cohesion, and familism in first-generation immigrant children. Longitudinal data from the Children of Immigrants Longitudinal Study (CILS) were used. The analytical sample (n = 5262) was predominantly female (51.1%) and between the ages of 12 and 18 (M = 14.23) years old. SPSS 27 and AMOS 27 were utilized to conduct a path analysis to examine the relationships among acculturation stress, self-esteem, depression, family cohesion, and familism. Our results showed good fit (χ2/df ratio = 11.49; CFI = 0.91; RMSEA = 0.05, CI [.04, .05]) for the full path model. Acculturation stress had a significant, negative association with depression (β = − 0.12, p < .001); a significant, negative association with self-esteem (β = − 0.12, p < .001); and a significant, positive association with family cohesion (β = 0.60, p < .01) and the familism index (β = 0.05, p < .05). Acculturation stress was found to be predictive of self-esteem, depression, and family cohesion for first-generation immigrant children between the ages of 12 and 18 years old. This study provides general implications for how mental health providers can understand the struggles and provide culturally competent therapeutic services for children and their families.
Inotuzumab ozogamicin for relapse prevention in a boy with Down syndrome and relapsed acute lymphoblastic leukemia
Authors: Kohso Atsushi , Toyoda Hidemi , Hanaki Ryo , Niwa Kaori , Okumura Yosuke , Morimoto Mari , Ito Takahiro , Hirayama Masahiro 
Published: December 2024

Abstract
Inotuzumab ozogamicin (InO), a CD22-directed antibody conjugated to calicheamicin, has demonstrated excellent efficacy in B-cell precursor (BCP) acute lymphoblastic leukemia (ALL). It has been used for patients with relapsed or refractory BCP-ALL as a bridge to allo-HCT. Children with Down syndrome (DS) have an increased risk of BCP-ALL and higher rates of relapse and toxicity, including treatment-related mortality. Although allo-HCT is potentially curative for relapsed or refractory ALL, post-transplant leukemic relapse rates and transplant-related mortality are dismal in patients with DS-ALL, which results in less frequent use of allo-HCT in this group than in the non-DS population. Therefore, novel and less toxic therapeutic strategies are required to improve outcomes. Here we report the case of a child with DS who was diagnosed with a second relapse of BCP-ALL and has maintained complete remission through regular single-agent InO therapy. Single-agent maintenance using InO can be a good option to avoid subsequent relapse in patients with relapsed or refractory BCP-ALL who cannot proceed to allo-HCT and require less-toxic treatments.
Twisted Adiabatic Limit For Complex Structures
Authors: Popovici Dan 
Published: December 2024

Abstract
Given a complex manifold X and a smooth positive function

$$\eta $$

η

thereon, we perturb the standard differential operator

$$d=\partial + \bar{\partial }$$

d
=
∂
+

∂

¯

acting on differential forms to a first-order differential operator

$$D_\eta $$

D
η

whose principal part is

$$\eta \partial + \bar{\partial }$$

η
∂
+

∂

¯

. The role of the zero-th order part is to force the integrability property

$$D_\eta ^2=0$$

D
η
2

=
0

that leads to a cohomology isomorphic to the de Rham cohomology of X, while the components of types

$$(0,\,1)$$

(
0
,

1
)

and

$$(1,\,0)$$

(
1
,

0
)

of

$$D_\eta $$

D
η

induce cohomologies isomorphic to the Dolbeault and conjugate-Dolbeault cohomologies. We compute Bochner-Kodaira-Nakano-type formulae for the Laplacians induced by these operators and a given Hermitian metric on X. The computations throw up curvature-like operators of order one that can be made (semi-)positive under appropriate assumptions on the function

$$\eta $$

η

. As applications, we obtain vanishing results for certain harmonic spaces on complete, non-compact, manifolds and for the Dolbeault cohomology of compact complex manifolds that carry certain types of functions

$$\eta $$

η

. This study continues and generalises the one of the operators

$$d_h=h\partial + \bar{\partial }$$

d
h

=
h
∂
+

∂

¯

that we introduced and investigated recently for a positive constant h that was then let to converge to 0 and, more generally, for constants

$$h\in \mathbb {C}$$

h
∈
C

. The operators

$$d_h$$

d
h

had, in turn, been adapted to complex structures from the well-known adiabatic limit construction for Riemannian foliations. Allowing now for possibly non-constant functions

$$\eta $$

η

creates positivity in the curvature-like operator that stands one in good stead for various kinds of applications.
Probabilistic Seismic Hazard Assessment for the North China Plain Earthquake Belt: Sensitivity of Seismic Source Models and Ground Motion Prediction Equations
Authors: Ma Jian , Goda Katsuichiro , Hong Han-Ping , Liu Kai , Xu Weijin , Cheng Jia , Wang Ming 
Published: December 2024

AbstractIn this study, a multi-source data fusion method was proposed for the development of a Hybrid seismic hazard model (HSHM) in China by using publicly available data of the 5th Seismic Ground Motion Parameter Zoning Map (NSGM) and historical seismic catalogues and integrating with modern ground motion prediction equations (GMPEs). This model incorporates the characteristics of smoothed seismicity and areal sources for regional seismic hazard assessment. The probabilistic seismic hazard for the North China Plain earthquake belt was investigated through sensitivity analysis related to the seismicity model and GMPEs. The analysis results indicate that the Hybrid model can produce a consistent result with the NSGM model in many cases. However, the NSGM model tends to overestimate hazard values in locations where no major events have occurred and underestimate hazard values in locations where major events have occurred. The Hybrid model can mitigate the degree of such biases. Compared to the modern GMPEs, the GMPE with epicentral distance measures significantly underestimate the seismic hazard under near-field and large-magnitude scenarios. In addition, a comparison of the uniform hazard spectra (UHS) obtained by the models, with China’s design spectrum, shows that the current design spectrum is more conservative than the calculated UHS.