bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relationship Between Online Game Addiction And Sleep Quality In Grade IX Junior High School Students
Authors: Nurannisa Isma Ayu , Mantu Melani Rakhmi 
Published: December 2024

Online game addiction is one of problems due to technology advancement such as digital devices and internet. Online games can be played indefinitely which lead addiction with symptoms such as not capable to control the desire of play game, having higher priority in playing game than other activities, and still choosing to play game even though knowing that there are negative effects. Online game addiction affects sleep duration that can lead to sleep quality problems. This research aims to investigate the association between online game addiction and sleep quality of 9th grade male students at SMPN 1 Kota Serang on January until March 2022. This research was conducted by using the analytic design with a cross sectional approach. Sampling used a consecutive sampling technique. The data was collected by using validated in Indonesian of Indonesia Online Game Addiction Questionnaire and Pittsburgh Sleep Quality Index and analyzed with chi square test in SPSS (Statistical Product and Service Solutions) version 22. The total sample obtained of 148 respondents and there is a significant association between online game addiction and sleep quality with p-value 0,000. This research concluded that online game addiction affects sleep quality.
Evaluasi Penggunaan Antibiotik pada Pasien Pneumonia Dewasa Rawat Inap di RSUD Nene Mallomo Kabupaten Sidrap
Authors: Hadiq Shabran , Fitriana Bunyanis  , Nur Astuti Wulandari  , Widiya Basri  
Published: December 2024

Pneumonia merupakan penyakit terbesar kedua setelah diare yang dapat menyebabkan kematian, dimana terjadi infeksi pada paru-paru yang disebabkan oleh mikroorganisme seperti bakteri, sehingga membutuhkan terapi antibiotik. Namun, beberapa studi mengemukakan bahwa satu per tiga antibiotik diresepkan tanpa indikasi yang jelas, dan hanya 21% yang diresepkan secara rasional. Tujuan dari penelitian ini adalah untuk mengetahui dan mengevaluasi penggunaan antibiotik pada pasien pneumonia dewasa rawat inap di Rumah Sakit Umum Daerah (RSUD) Nene Mallomo tahun 2023. Penelitan ini menggunakan rancangan studi kuantitatif dan pengumpulan data secara retrospektif. Data yang didapatkan sebanyak 35 sampel yang memenuhi kriteria inklusi dan eksklusi dan akan dievaluasi menggunakan metode gyssens. Hasil penelitian menunjukkan bahwa profil penggunaan antibiotik untuk terapi tunggal yang paling banyak adalah Ceftriaxone sebanyak 18 (52,94%). Sedangkan untuk terapi kombinasi yang paling sering digunakan adalah Ceftriaxone+Levofloxacin sebanyak 3 (8,82%). Hasil evaluasi penggunaan antibiotik menunjukkan terdapat 37,5% penggunaan antibiotik rasional (Kategori 0), dan sebanyak 62,5% penggunaan antibiotik yang tidak rasional (Kategori IV-I). Dari hasil tersebut dapat disimpulkan bahwa penggunaan antibiotik tersebut berdasarkan metode gyssens belum rasional. Perlu dilakukan penelitian lanjutan menggunakan metode evaluasi yang lain dan juga terkait faktor-faktor yang menyebabkan penggunaan antibiotik belum rasional.
Hubungan Efikasi Diri dengan Kesiapsiagaan Bencana pada Mahasiswa Kesehatan Universitas Respati Yogyakarta
Authors: Tia Amestiasih  , Murdhiono Wahyu Rochdiat , Herry Soetjipto Sri Tanjung Saroyo 
Published: December 2024

Latar Belakang: Daerah Istimewa Yogyakarta (DIY) merupakan salah satu wilayah di Indonesia yang rawan terjadi bencana alam, diakibatkan karena adanya gunung berapi aktif serta beberapa daerah berbatasan dengan laut. Mahasiswa kesehatan Universitas Respati Yogyakarta (UNRIYO), sebagai calon tenaga kesehatan yang menjadi role model di masyarakat serta bertanggungjawab mempersiapkan diri dalam memberikan pelayanan kesehatan yang optimal bagi korban bencana, dituntut memiliki tingkat kesiapsiagaan bencana yang tinggi. Efikasi diri merupakan salah satu faktor yang mempengaruhi kesiapsiagaan bencana pada individu. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan efikasi diri dengan kesiapsiagaan bencana pada mahasiswa kesehatan UNRIYO. Metode: Metode penelitian yang digunakan adalah kuantitatif non eksperimental dengan desain cross sectional, tipe correlation research. Sampel berjumlah 305 mahasiswa fakultas ilmu kesehatan UNRIYO yang diambil melalui teknik proportionate stratified random sampling. Data diambil melalui pembagian kuisioner kemudian dianalisis menggunakan uji chi square. Hasil: Hasil dalam penelitian ini sebagaian besar reponden memiliki tingkat efikasi diri tinggi 92,5% dan kesiapsiagaan bencana dalam kategori siap 96,1%. Hasil pembacaan Fisher’s exact didapat p value = 0,226 (p value > 0,005). Kesimpulan: Tidak terdapat hubungan antara efikasi diri dengan kesiapsiagaan bencana mahasiswa kesehatan Universitas Respati Yogyakarta.
Pengaruh Beban Kerja terhadap Stress Kerja Perawat di Ruang Rawat Inap RSUD dr. Soekardjo Kota Tasikmalaya
Authors: Cahyati Peni , Kartilah Tetet , Djamiatul Heri , Hartono Dudi , Adini Syaukia 
Published: December 2024

Pelayanan rumah sakit dituntut meningkatkan mutu dan kualitas dalam menunjang kesehatan individu dan masyarakat, Mutu pelayanan rumah sakit sangat di pengaruhi oleh beberapa faktor, diantaranya yang paling dominan adalah sumber daya manusia dan salah satunya adalah tenaga perawat. Perawat dituntut untuk meningkatkan kualitas pelayanan kesehatan kepada pasien, beban tugas perawat yang meningkatka dapat menyebabkan timbulnya stres. Stres kerja yang muncul dan tidak ditangani dengan baik tentu akan berdampak, baik bagi fisiologis, psikologis maupun sikap. Penelitian ini bertujuan untuk melihat pengaruh beban kerja terhadap stress kerja, dengan jumlah sampel 60 orang perawat yang bekerja di ruang rawat inap. Metode penetian yang akan digunakan dalam penelitian ini adalah metode survey dengan jenis penelitian asosiatif kausal dengan jenis data kuantitatif, menggunakan pendekatan deskriptif dan verifikatif. Hasil penelitian ini adalah beban kerja dan stres kerja perawat dalam katagori sedang dan ada pengaruh antara beban kerja terhadap stres kerja
Yönetim ve Organizasyon
Authors: Yücel Mustafa , Canbolat Mehmet Ali , Aksu Bora , Erkasap Ahmet , İçerli Leyla , Yılmaz Feride , Özdemir Adem , Yücel Derya , Öcal Hülya , Karakaplan Özer Emine 
Published: December 2024

Yönetim Kavramı ve Tarihsel Gelişimi
Mustafa YÜCEL
Yönetim Fonksiyonları ve Güncel Tartışmalar
Mustafa YÜCEL
Örgüt Yapıları ve Tasarımı
Mehmet Ali CANBOLAT
Liderlik ve Motivasyon
Mustafa KESEN
Karar Verme Süreci ve Stratejik Yönetim
Bora AKSU
İnsan Kaynakları Yönetimi
Ahmet ERKASAP
Örgütsel İletişim ve İletişim Stratejileri
Leyla İÇERLİ
Örgütsel Kültür ve Değişim Yönetimi
Feride YILMAZ
Stratejik İnsan Kaynakları Yönetimi
Adem ÖZDEMİR
İnovasyon ve Girişimcilik
Derya YÜCEL
Etik ve Sosyal Sorumluluk
Hülya ÖCAL
Küresel Yönetim ve Uluslararası İşletmecilik
Emine KARAKAPLAN ÖZER
EFFECTIVENESS OF AVOCADO SEED EXTRACT (Persea americana Mill.) ON INHIBIT GROWTH OF Candida albicans AND Trichopyton sp.
Authors: Marsus Ismat , Nur Muhammad Khaerul , Fahruddin  , Baharuddin Suherman 
Published: December 2024

In the world of medicine, avocados (Persea americane Mill.) are mostly used as traditional medicine in treating various diseases, but in the avocado seed it turns out that so far, it has only been left and thrown away, even though it contains secondary metabolite compounds that can be used as medicinal ingredients, including alkaloids, flavonoids, tannins, saponins, phenolics, terpenoids, and steroids. This study aimed to determine the effectiveness of an avocado seed extract (Persea americana Mill.) concentrations of 5% 10% and 15% b/v against the growth of Candida albicans and Trichopyton sp. and determine at what concentration is most effective. This research is experimental which is a laboratory study using the method of extraction by maceration and disc diffusion (Kirby-Bauer Test) in testffectiveness of avo (Persea americana Mill.) against the growth of Candida albicans and Trichopyton spto testlts obtained from the avocadoment of the diameter of the inhibition were analyzed by one-way analysis of variance (ANOVA) and correlation test using the IBM SPSS Statistics version 26 program. The results showed that avocado seed extract (Persea americana Mill) was effective in inhibiting the growth of Candida albicans and Trichopyton sp. The most effective concentration was at a concentration of 15% b/v, respectively, where the inhibition of Candida albicans was 11.84 ± 0.238 mm while the inhibition of Trichopyton sp. was 12.58 ± 0.005 mm (oneway Anova, ? = 0.05)
Keywords: Effectiveness, Persea americana Mill, Candida albicans, Trichopyton sp., Kirby- Bauer
Perspectiva de la Medicina Fetal en la era de la genómica prenatal
Authors: Herrera Tania T. 
Published: December 2024

En las últimas décadas, la medicina prenatal ha incorporado progresivamente diferentes tecnologías de diagnóstico que han logrado complementar los métodos existentes. Técnicas citogenéticas tales como el cariotipo han sido complementadas con novedosas técnicas moleculares de alta resolución, permitiendo así identificar cambios genómicos con resolución de nucleótidos individuales. Alguna de estas técnicas incorporada a la evaluación de casos prenatales son el QF-PCR, la hibridación genómica comparativa (arreglo CGH), diferentes métodos de secuenciación masiva paralela, entre otras.

Actualmente estas tecnologías moleculares para el diagnóstico prenatal estan siendo implementadas en nuestra región desde en la última década. Todo proceso de implementación trae consigo ventajas y retos intrínsecos de cada tecnología, y el equipo multidisciplinario debe manejar con claridad las indicaciones de su uso y las implicaciones posterior a la generación de resultados. En este trabajo presentamos algunas de las consideraciones por parte del Colegio Americano de Medicina Genética y Genómica y la Sociedad Internacional de Diagnóstico Prenatal en cuanto a las indicaciones de estas pruebas moleculares y la consejería post-prueba. Esto permitirá al personal de salud involucrado en las mismas su implementación eficaz, y la obtención de un mayor beneficio para el paciente.
Detección de una variante genética del Síndrome de Apert
Authors: Lynett Daniela , Lubo López María Paola , Rojas Arbelaez Laura Andrea , Rodríguez Ocampo Paula Andrea , Ramirez Lev Bladimir , Jimenez Daniel , Celis Regalado Luis Gustavo , Fonque Ojeda Nathalia , García Montoya Gabriela 
Published: December 2024

Introducción: El síndrome de Apert (SA), o acrocefalosindactilia tipo I, es un trastorno congénito autosómico dominante causado por una mutación en el gen FGFR2, esencial durante el desarrollo embrionario. Se caracteriza por craneosinostosis, hipoplasia del tercio medio facial y sindactilia. Aunque es poco frecuente, su incidencia es de 1/100,000 a 1/160,000 nacidos vivos, con una prevalencia de 1 a 9 casos por cada 100,000 personas. El diagnóstico prenatal es complejo debido a su similitud con otros síndromes congénitos. Objetivo: Este artículo analiza la caracterización genética y molecular de una paciente diagnosticada con Síndrome de Apert. Metodología: Se obtuvo consentimiento informado y se realizó la historia clínica y examen físico. Se recolectaron muestras de sangre para exámenes paraclínicos y moleculares, así como estudios de imagen. Resultados: Los resultados mostraron características fenotípicas compatibles con el síndrome, como estrabismo, proptosis y craneosinostosis tipo plagiocefalia anterior. Los estudios genéticos detectaron una variante patogénica en el gen FGFR2 (c.755C>G) y una variante de significado incierto (c.532C>T). Discusión: La mutación FGFR2 (c.755C>G) es una de las más frecuentes en el SA y se sugiere que afecta la especificidad del receptor, conduciendo a la supresión de la apoptosis de osteoblastos, resultando en las características fenotípicas del síndrome. Conclusión: Aunque la variante de significado incierto (c.532C>T) presenta características deletéreas, no se han reportado otros casos con esta variante. Actualmente, la paciente no ha presentado deterioro adicional y el pronóstico sigue siendo incierto. Se considera necesario ampliar los estudios moleculares para investigar esta nueva variante y sus implicaciones clínicas.
JWST Validates HST Distance Measurements: Selection of Supernova Subsample Explains Differences in JWST Estimates of Local H
0
Authors: Riess Adam G. , Scolnic Dan , Anand Gagandeep S. , Breuval Louise , Casertano Stefano , Macri Lucas M. , Li Siyang , Yuan Wenlong , Huang Caroline D. , Jha Saurabh , Murakami Yukei S. , Beaton Rachael , Brout Dillon , Wu Tianrui , Addison Graeme E. , Bennett Charles , Anderson Richard I. , Filippenko Alexei V. , Carr Anthony 
Published: December 2024

Abstract
We cross-check the Hubble Space Telescope (HST) Cepheid/Type Ia supernova (SN Ia) distance ladder, which yields the most precise local H
0, against early James Webb Space Telescope (JWST) subsamples (∼1/4 of the HST sample) from SH0ES and CCHP, calibrated only with NGC 4258. We find HST Cepheid distances agree well (∼1σ) with all combinations of methods, samples, and telescopes. The comparisons explicitly include the measurement uncertainty of each method in NGC 4258, an oft-neglected but dominant term. Mean differences are ∼0.03 mag, far smaller than the 0.18 mag “Hubble tension.” Combining all measures produces the strongest constraint yet on the linearity of HST Cepheid distances, 0.994 ±0.010, ruling out distance-dependent bias or offset as the source of the tension at ∼7σ. However, current JWST subsamples produce large sampling differences in H0 whose size and direction we can directly estimate from the full HST set. We show that ΔH
0 ∼ 2.5 km s−1 Mpc−1 between the CCHP JWST program and the full HST sample is entirely consistent with differences in sample selection. We combine all JWST samples into a new distance-limited set of 16 SNe Ia at D ≤ 25 Mpc. Using JWST Cepheids, JAGB, and tip of the red giant branch, we find 73.4 ± 2.1, 72.2 ± 2.2, and 72.1 ± 2.2 km s−1 Mpc−1, respectively. Explicitly accounting for common supernovae, the three-method JWST result is H
0 = 72.6 ± 2.0, similar to H
0 = 72.8 expected from HST Cepheids in the same galaxies. The small JWST sample trivially lowers the Hubble tension significance due to small-sample statistics and is not yet competitive with the HST set (42 SNe Ia and 4 anchors), which yields 73.2 ± 0.9. Still, the joint JWST sample provides important cross-checks that the HST data pass.
Effects of Ocular Residual Astigmatism on Refractive Outcomes for Myopia Correction After Keratorefractive Lenticule Extraction Surgery
Authors: Su Qing , Liang Shuang , Cao Huazheng , Shan Mengyuan , Wang Yan 
Published: December 2024

Purpose
To evaluate the effects of ocular residual astigmatism (ORA) on refractive outcomes for patients with astigmatism after keratorefractive lenticule extraction (KLEx) and to identify the ratio of the ORA/manifest refractive cylinder at the corneal plane (MRC) resulting in a greater index of success (IOS).

Methods
In total, 892 right eyes that underwent KLEx surgery were included. Astigmatic changes were evaluated using Alpins' vector analysis. Surgical outcomes grouped by ORA/MRC and ORA were compared. In stage 1, eyes were divided into two groups with an ORA/MRC cutoff value of 1. In stage 2, patients with an ORA/MRC ratio of greater than 1 were divided into two groups: those with an ORA of 1.25 diopters (D) or greater and those with an ORA of less than 0.50 D. ORA/MRC thresholds leading to a high IOS were analyzed using receiver operating characteristic (ROC) curves.

Results

In stage 1, the mean IOS was 0.13 and 0.21 for the low and high ORA/MRC groups, respectively (
P
< .001). In stage 2, for high ORA/MRC, the IOS was significantly greater when the ORA was greater than 1.25 D than when the ORA was less than 0.50 D (0.27 versus 0.13,
P
< .001). ROC curves revealed that participants with an ORA/MRC ratio of greater than 1.8 were more likely to have a higher IOS (
P
< .001).

Conclusions
Patients with a smaller ORA can obtain better correction results. An ORA/MRC ratio of greater than 1.8 may increase the risk of poor astigmatism correction with KLEx. The application of vector planning may improve the refractive outcomes of KLEx.

[
J Refract Surg
. 2024;40(12):e966–e973.]
Eddington philosophe
Authors: Laguens Florian 
Published: December 2024

Unanimement considéré comme l'astronome le plus influent de l'entre-deux-guerres, Arthur S. Eddington (1882-1944) participa aux premières confirmations expérimentales de la théorie de la relativité d'Einstein. On sait moins que son rôle fut décisif pour l’émergence des premiers modèles d’univers en expansion, à l’origine de la théorie du Big Bang. Acteur et témoin des principales révolutions scientifiques du XXe siècle que furent la théorie de la relativité et la mécanique quantique, Arthur Eddington a aussi investi le champ épistémologique par plusieurs ouvrages majeurs, et fut un philosophe de la physique parmi les plus lus de son temps.Explorant l’intégralité des œuvres du physicien ainsi que de nombreux documents inédits, Florian Laguens dresse à travers cette étude un portrait riche et précis de la philosophie d’Eddington. Se déploie peu à peu une conception stimulante de la nature et de la portée de la science physique, parfois déroutante mais non sans cohérence, à condition de la reconduire à ses intuitions originaires. Au fil du texte se noue un dialogue à trois niveaux : d’abord entre les œuvres mêmes d’Eddington, de sorte à manifester les grandes phases de sa réflexion sur la signification du monde physique. Ensuite, entre les composantes de la vie d’Eddington, à la fois scientifique, philosophique et religieuse. Finalement, avec trois inspirateurs : Bertrand Russell, Emmanuel Kant et René Descartes.Eddington révèle ainsi la profondeur de ses intuitions, l’originalité de sa démarche et l’actualité de sa pensée.Préface de Michel Bitbol
Examining the unidimensionality of the PHQ-9 with first responders: Evidence from different psychometric paradigms
Authors: Pretorius Tyrone B. , Padmanabhanunni Anita 
Published: December 2024

The Patient Health Questionnaire-9 (PHQ-9) is an effective tool for identifying depressive disorders in diverse populations, making it a valuable resource in both clinical practice and research. However, the factor structure and dimensionality of the instrument have been contested. Studies have raised questions about whether the PHQ-9 adequately captures a single underlying construct or reflects multiple distinct dimensions of depression. This study examines the factor structure of the PHQ-9 among South African first responders using exploratory factor analysis (EFA), confirmatory factor analysis (CFA) with ancillary bifactor indices, parallel analysis and Mokken analysis. A cross-sectional study design was used with data collected from police officers (n = 309) and paramedics (n =120). Although the EFA identified a two-factor structure, this was not supported by the other analyses. While the one-factor, correlated two-factor and bifactor models of the PHQ-9 had comparable fit indices, the one-factor model appeared to be marginally superior in the CFA. Ancillary bifactor and parallel analysis also did not support the interpretation of the PHQ-9 as multidimensional. Lastly, Mokken scale analysis confirmed that the PHQ-9 is a strong and reliable unidimensional scale of depression. These findings suggest that the PHQ-9 predominantly measures a single construct of depression, consistent with the unidimensional view of the disorder.Contribution: The present study provides evidence from different measurement perspectives that the commonly used PHQ-9 measures a single construct of depression and not two separate components as some studies suggested. In practice, this simplifies the interpretation of scores, allowing clinicians to assess overall depression severity without needing to differentiate between symptom types.
Influence of personality and psychological capital on managers’ trust in their direct–reports
Authors: Zaayman Christopher H. , Motala Tasneem 
Published: December 2024

Purpose: This article investigates the influence of a manager’s psychological capital (Psycap) and Personality Traits, based on the Five Factor Model (FFM), on their Propensity to Trust their direct-reports. While most literature focuses on subordinates’ trust in managers, this study explores the reverse. It stems from the need to enhance organisational performance by improving trust between managers and subordinates.Design/methodology/approach: The study uses a quantitative approach with established scales: Nyhan and Marlowe’s Trust Measurement Scale, the TIPI Scale for personality, and the Psycap Questionnaire-12. Data were primarily collected from managers in South African manufacturing firms.Findings/results: Psycap was the strongest driver of trust, showing a significant positive link to managers’ trust in direct-reports. Agreeableness and Emotional Stability show significant positive relationships with trust, though at a lower confidence level, while Conscientiousness, Extraversion, and Openness do not show significant links.Practical implications: The findings highlight the need for targeted training to improve managers’ interpersonal, emotional regulation, and trust-building skills. Performance evaluations should consider trust-building behaviours and promotion policies could be refined based on the research findings, to ensure that candidates who are suitable for leading successful teams are placed in managerial positions.Originality/value: The study contributes nuanced insights by challenging traditional perspectives on Personality Traits and Trust, emphasising the vital role of Psycap in trust propensity. The study shows that investing in employee Psycap development is crucial. Employees with higher Psycap levels tend to trust their direct-reports more, which helps build a positive organisational culture that prioritises psychological well-being.
Comparative Analysis of Sleep Quality between Medical and Nonmedical Students at Gulu University, Uganda
Authors: Nakitto Brenda , Nansubuga Federes , Omondi Edward , Opedo Moses , Bongomin Felix 
Published: December 2024

Abstract

Background:
Adequate sleep is essential for overall health and well-being, and poor sleep quality significantly affects academic performance. In this study, we evaluated and compared the quality of sleep among medical and nonmedical students at Gulu University in Uganda.

Methods:
We conducted a cross-sectional study recruiting undergraduate students of Gulu University, Gulu, Uganda. Data were collected using self-administered questionnaires. Pittsburgh Sleep Quality Index (PSQI) and Patient Health Questionnaire-9 (PHQ-9) were used to assess sleep quality and depression, respectively. PSQI score >5 defined poor sleep quality and PHQ-9 score ≥5 depression. Multivariable logistic regression analysis was used to identify independent predictors of poor sleep quality. P <0.05 was considered statistically significant.

Results:
Of the 513 participants enrolled, 199 (38.8%) were female, with a median age of 23 (interquartile range: 22–25) years. Overall, 395 (77.0%) students had poor sleep quality (nonmedical students 317 [80.3%] vs. medical students 78 [19.8%], P = 0.023). The prevalence of symptoms of depression was 57.7% (n = 296) and was significantly higher among those with poor sleep quality compared to those with good sleep quality (259 [65.6%] vs. 37 [31.4%], P < 0.001). The odds of having poor sleep quality were over 4-fold higher among students with symptoms of depression than those without (adjusted odds ratio: 4.31, 95% confidence interval: 2.45–7.60, P < 0.001).

Conclusions:
The study findings reveal a high prevalence of poor sleep quality and depression among students at Gulu University. Routine screening of sleep quality and depressive symptoms is necessary to control and prevent their impact on the performance and well-being of university students.