bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biocompatible Polymers and their Potential Biomedical Applications: A Review
Authors: Arif Uzma , Haider Sajjad , Haider Adnan , Khan Naeem , Alghyamah Abdulaziz A. , Jamila Nargis , Khan Muhammad Imran , Almasry Waheed A. , Kang Inn-Kyu 
Published: October 2019

Background:
Biocompatible polymers are gaining great interest in the field of biomedical applications.
The term biocompatibility refers to the suitability of a polymer to body and body fluids exposure. Biocompatible
polymers are both synthetic (man-made) and natural and aid in the close vicinity of a living system or work in
intimacy with living cells. These are used to gauge, treat, boost, or substitute any tissue, organ or function of the
body. A biocompatible polymer improves body functions without altering its normal functioning and triggering
allergies or other side effects. It encompasses advances in tissue culture, tissue scaffolds, implantation, artificial
grafts, wound fabrication, controlled drug delivery, bone filler material, etc.

Objectives:
This review provides an insight into the remarkable contribution made by some well-known biopolymers
such as polylactic-co-glycolic acid, poly(ε-caprolactone) (PCL), polyLactic Acid, poly(3-
hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), Chitosan and Cellulose in the therapeutic measure for many
biomedical applications.

Methods: :
Various techniques and methods have made biopolymers more significant in the biomedical fields such
as augmentation (replaced petroleum based polymers), film processing, injection modeling, blow molding techniques,
controlled / implantable drug delivery devices, biological grafting, nano technology, tissue engineering
etc.

Results:
The fore mentioned techniques and other advanced techniques have resulted in improved biocompatibility,
nontoxicity, renewability, mild processing conditions, health condition, reduced immunological reactions and
minimized side effects that would occur if synthetic polymers are used in a host cell.

Conclusion:
Biopolymers have brought effective and attainable targets in pharmaceutics and therapeutics. There
are huge numbers of biopolymers reported in the literature that has been used effectively and extensively.
Genistein Decreases APP/tau Phosphorylation and Ameliorates Aβ Overproduction Through Inhibiting CIP2A
Authors: Shentu Yang-Ping , Hu Wen-Ting , Liang Jia-Wei , Liuyang Zhen-Yu , Wei Hui , Qun Wang , Wang Xiao-Chuan , Wang Jian-Zhi , Westermarck Jukka , Liu Rong 
Published: October 2019

Background:
Upregulation of Cancerous Inhibitor of PP2A (CIP2A) plays an important role
in disease-related phosphorylation of tau/APP and tau pathology/Aβ overproduction through inhibiting
PP2A in AD brain. Genistein has been shown to potently reduce CIP2A in experimental cancer treatment
research. Whether Genistein can ameliorate AD pathology through targeting CIP2A needs further investigation.

Methods:
The inhibitory effects of Genistein on tau/APP phosphorylation and Aβ overproduction in AD
cell models have been explored. HEK293-T cells were co-transfected with CIP2A and APP plasmids, or
CIP2A and tau plasmids, with Genistein incubation at 0, 30, 60 or 120 µM for 48 h, cell viability and
PP2A activities were measured. HEK293-T cells with CIP2A/APP overexpression treated with Genistein
at 30 µM for 48 h were collected and lyzed for Western blotting detection of CIP2A, PP2Ac, APP-T668,
total APP, PS1, BACE1, sAPPα and sAPPβ. Aβ40 and Aβ42 levels in cell supernatant, soluble fraction
(RIPA) and insoluble fraction (formic acid soluble) of cell lysates were measured by ELISA. HEK293-T
cells with CIP2A/tau overexpression treated with Genistein at 30 µM for 48 h were collected for Western
blotting detection of CIP2A, PP2Ac, tau-S396, tau-S404 and total tau.

Conclusion:
CIP2A is a target of Genistein in AD therapy. Genistein reduces APP/tau hyperphosphorylation
and Aβ production through inhibiting the effect of CIP2A on PP2A.

Results:
Genistein effectively reduced CIP2A expression, and restored PP2A activities both in
CIP2A/APP, CIP2A/tau co-expressed cells. Genistein reduced APP phosphorylation at T668 site and
inhibited Aβ production. Meantime, Genistein ameliorated tau hyperphosphorylation through repressing
the inhibitory effect of CIP2A on PP2A.
Enhanced Mseec Routing Protocol Involving Tabu Search with Static and Mobile Nodes in Wsns
Authors: Sahni Varsha , Bala Manju , Kumar Manoj 
Published: October 2019

Background:
Background of this paper has taken place in mainly heterogeneous network
in which three types of nodes are present like normal node, advance node and super node with different
amount of energy. The energy of super node is greater than that of advance and normal nodes
and the energy of advance nodes are also greater than that of normal nodes in the designed network.
The optimization techniques have to be studied from the swarm intelligence based on the different
aspects of routing.

Objective:
The objective of this paper is to propose a new heterogeneous protocol with the help of
hybrid meta-heuristic technique. In this technique, the shortest route has been selected and forwarded
the data to the sink in a minimal time span to save the energy and make the network more stable.

Methods:
To evaluate the technique, a new hybrid technique has been created, where the data
transmission is implemented from the beginning. This technique contains the route process of the
algorithm which was made available through a hybrid meta-heuristic technique.

Results:
Simulation results show that the hybrid meta-heuristic technique has high throughput with
less number of dead nodes with existing methods and also show that the efficiency and stability of
new proposed protocol.

Conclusion:
The conclusion to this paper is a novel, energy-efficient technique applied for randomly
deployed sensor nodes over the wireless sensor network and enhancement has been done in stability
and throughput of a new proposed algorithm in case of static as well as moving nodes.
Meningkatkan Kemampuan Membaca Huruf Jawa Legena Melalui Media Komputer Siakna Bagi Tunagrahita Ringan
Authors: Winoto Bekti 
Published: October 2019

Penelitian ini bertujuan meningkatkan kemampuan membaca huruf Jawa “legena” melalui media komputer “SIAKNA” bagi siswa tunagrahita ringan. Penelitian ini dilaksanakan di kelas VII B SMPLB SLB Negeri 1 Yogyakarta tahun ajaran 2018/2019. Penelitian ini merupakan penelitian tindakan kelas dengan desain penelitian Suharsimi Arikunto. Subjek penelitian adalah 3 peserta didik. Penelitian ini terdiri dari 3 siklus. Metode analisis data yang digunakan adalah deskriptif kualitatif dan penyajian data dalam bentuk tabel dan grafik. Hasil penelitian menunjukkan penggunaan media komputer SIAKNA dapat meningkatkan kemampuan membaca huruf Jawa legena dengan prosentase 95%. Kesimpulannya penggunaan media komputer “SIAKNA” dapat meningkatkan kemampuan membaca huruf Jawa legena siswa kelas VII B SLB Negeri 1 Yogyakarta.
Comments of the Auditing Standards Committee of the Auditing Section of the American Accounting Association on Proposed Statement on Auditing Standards (SAS), Audit Evidence
Authors: Brown Veena Looknanan , Dickins Denise , Hermanson Dana R. , Higgs Julia L. , Jenkins J. Gregory , Nolder Christine , Schaefer Tammie J. , Smith Kecia Williams 
Published: October 2019

SUMMARY
On June 20, 2019, the American Institute of Certified Public Accountants Auditing Standards Board (the Board or ASB) issued a request for comment on its Exposure Draft, Proposed Statement on Auditing Standards, Audit Evidence. Enhancements in the proposed SAS include the use of emerging technologies by both preparers and auditors, audit data analytics, the application of professional skepticism, and the expanding use of external information sources as audit evidence. The comment period ended on September 18, 2019. This commentary summarizes the participating committee members' views on selected questions posed by the ASB. Questions not addressed by the committee are listed at the end of this manuscript.
Data Availability: Proposed Statement on Auditing Standards (SAS), Audit Evidence, including questions for respondents, is available at: https://www.aicpa.org/content/dam/aicpa/research/exposuredrafts/accountingandauditing/downloadabledocuments/20190620a/20190620a-ed-sas-audit-evidence.pdf
Política social, desarrollo territorial o trampa de pobreza: Caso Mártir de Cuilapan, Guerrero
Authors: Sánchez Ignacio Iván , Tello Almaguer Pedro Vidal 
Published: October 2019

La política social es un mecanismo cuyo propósito es establecer o crear condiciones de equidad social, promoviendo el ejercicio de los derechos sociales y la incorporación de los beneficiarios a un modelo de desarrollo basado en el emprendimiento. El objetivo de la presente investigación es analizar si el gasto público ejercido en Mártir de Cuilapan, Guerrero, en el marco de la Cruzada Nacional contra el Hambre (CNCH), cumplió con la finalidad de desarrollar y fortalecer las principales ramas económicas del municipio. Para ello se revisaron planteamientos teóricos en torno a la política social, sustentabilidad, territorio, territorialización y trampa de pobreza, conceptos básicos para el análisis de la política social. Asimismo, se recopiló información a través de entrevistas estructuradas y semiestructuradas; y bases de datos de los beneficiarios de dependencias federales, así como información del censo económico 2014 de Instituto Nacional de Estadística y Geografía (Inegi).
Como resultado de las entrevistas y la elaboración de la tipología de las actividades económicas del municipio, se observa que el impacto del gasto público realizado en el marco de la CNCH no fue el esperado: La mayoría de los sectores económicos del municipio son parte del sector no básico de la economía, tienen una posición no dinámica y no tienen un desempeño competitivo; solo los sectores económicos 31-32, referentes a industrias manufactureras, son parte del sector básico de la economía. Por lo tanto, la mayoría de los sectores económicos tienen una posición dinámica y un desempeño no competitivo. El mayor gasto público se orientó a las comunidades rurales de la localidad, y los resultados obtenidos muestran que el territorio y su realidad son elementos que imponen la necesidad de repensar los enfoques de la política social.
Instrumento certificador de tecnologías de la información y comunicación y tecnologías del aprendizaje y el conocimiento para docentes universitarios
Authors: González Jaimes Elvira Ivone , López Chau Asdrubal , Trujillo Mora Valentín , Bautista López Jorge 
Published: October 2019

Este artículo presenta los resultados de la investigación cuyo objetivo consistió en la elaboración de un instrumento innovador, ágil, veraz y confiable para evaluar y certificar al personal académico universitario. Un instrumento capaz de detectar cuatro niveles de conocimientos y uso en tecnologías de la información y la comunicación (TIC) y tecnologías del aprendizaje y el conocimiento (TAC).
Se trató de un estudio cuasiexperimental dividido en tres fases: a) elaboración de la prueba con diseño mixto transformativo secuencial; b) evaluación de la prueba con diseño mixto secuencial, y c) sistematización con App Ionic 3.
Una vez realizados los análisis cualitativos y cuantitativos, el instrumento resultó versátil y transferible en 1) selección y contratación de personal, 2) identificar el nivel conocimientos que tiene el personal, 3) crear programas y/o cursos que refuerce o cree nuevas habilidades en TIC y TAC, 4) categorizar al personal de acuerdo su nivel de conocimientos, 5) promocionar al personal para adquirir beneficios o prestaciones laborales, 6) evidenciar el nivel que tiene los académicos en la evaluación que realizan los organismos acreditadores y 7) constancia curricular de posesión de nivel de conocimiento y uso en TIC y TAC en área académica.
Dicha prueba puede ser aplicable de forma individual o colectiva y obtener calificaciones a través de un método manual, por lo que se anexa una guía de usuario, o electrónico, para lo cual se requiere solicitar la página web a los autores.
Relación entre el no cumplimiento de las normas de atención del parto culturalmente adecuado y las complicaciones materno–neonatales
Authors: Quinaluisa Mercedes , Rosero Mercy 
Published: October 2019

La Guía de Atención de Parto Culturalmente adecuado es una herramienta de seguimiento de maternidades de corta estancia en el primer nivel. Se realizó un estudio transversal con 92 casos de maternidad y 25 miembros del personal de salud de enero a febrero de 2016. Se realizaron encuestas con 121 variables para los análisis y se construyeron las puntuaciones porcentuales para: comprensión, aceptación, aplicación del estándar y calidad en registros médicos. Por lista de veri cación se evaluaron las unidades de trabajo de infraestructura y equipo, entrega y recuperación.
El personal conoce reglas y protocolos en un 73%, según la aplicación de la norma que fue del 83% (de acuerdo a los registros médicos). Las complicaciones en el parto, para las madres fueron: anemia (36%), desgarro vaginal de primer grado (21%), hipotonía uterina (15%); en recién nacidos: presentación compuesta (32%), circular de cordón (25%), líquido meconial leve (12%). En cuanto a la unidad de trabajo, infraestructura y equipo, entrega y recuperación, estuvo equipado en un 46% y 37% de infraestructura en relación con el estándar. Había un conocimiento regular sobre la base legal de las regulaciones (38%), y el cumplimiento no se alcanzó lo recomendado (90%). Cuando no se aplicó la regla porque generaba incomodidad al que asistía al parto y no tenía habilidades para ello, así como al evaluar la satisfacción del usuario, se observó que la mitad del personal implementaba parcialmente las disposiciones.
Por análisis bivariado identi có que no hubo relación entre la aplicación de las reglas y las complicaciones materno-neonatales, tampoco hubo asociación estadísticamente signi cativa entre la calidad percibida cuando se presentaron complicaciones neonatales pero si hubo percepción de calidad asociada a complicaciones ma- ternas. La unidad de evaluación Carapungo II, mostró los factores que in uyeron en su incumplimiento y las complicaciones maternas y neonatales.
Effect of Black Liquor from Date Palm on the Workability and Compressive Strength of Portland Cement and Concrete
Authors: Irekti A. , Oualit M. , Siahmed H. , Buncianu D. , Zibouche F. 
Published: October 2019

Abstract
Lignin is the second most abundant natural polymer. Due to the high content of carbon and hydrogen (C-H, C-C, C=O), it can be used as a potential dispersant for cement matrix. The objective of this study is to extract lignin from date palm and study its effect in the form of black liquor (BL) on the rheological and physic-mechanical properties of the cements and concrete. The lignin in black liquor form represents approximately 30 wt% dry weight of date palm. It is a heteropolymer composed primarily of methoxylated phenylpropylene alcohol monomeric units interconnected by a variety of stable carbon-carbon and carbon-oxygen-carbon (ether and esters) linkages. The results found show the positive effect on the workability of cement and concrete and confirms its dispersion effect by improving compressive strength of concrete during the early and the later ages of hydration.
A Fuzzy Adaptive Nonlinear Control for an Asynchronous Machine
Authors: Fatima Moulay , Assia Habbatti , Habib Hamdaoui 
Published: October 2019

Abstract
This paper presents the general concept of the nonlinear control of the asynchronous machine. The decoupling between the flux and the speed is realized by the input-output linearization technique. In this work, a nonlinear adaptive control method has been applied to the asynchronous machine and we give some initial results on the adaptive fuzzy logic control of nonlinear systems, linearized by state feedback. The adaptations of the parameters are used as a technique for robustifying the exact cancellation of the nonlinear terms, which is called for the linearization technique. The performance of the proposed nonlinear adaptive control scheme is demonstrated by simulation results. These results show that the proposed method achieves the desired dynamic performance.
SoC as IoT sensor network hub
Authors: Alexan Alexandru , Alexan Anca , Ștefan Oniga , Tisan Alin 
Published: October 2019

Abstract
Nowadays SoC’s miniaturization provide smaller yet more powerful devices that are perfect to be used as local hubs for small to medium sensor networks. Although sensors can now be easily connected directly to the cloud, a hub can simplify the process of bringing sensor to the IoT cloud. One of the most popular SoC board, Raspberry PI, is perfect for the hub role due to its small form factor, price, processing power and connectivity. Our proposed system consists in a SoC based low cost raspberry pi hub that connects two Bluetooth sensortag CC2650 modules to a mongoDB cloud database.
Old-Age Pension Insurance in ZUS and KRUS in the Context of the Insured and Public Finances
Authors: Podstawka Łukasz 
Published: October 2019

Summary

Subject and purpose of work: The subject of this paper was to assess the old-age pension insurance in ZUS (Social Insurance Institution) and KRUS (Agricultural Social Insurance Fund) from the perspective of a person insured and the public finances. The purpose of the study was to calculate the difference in saving efficiency of the insured in ZUS and KRUS.

Materials and methods: The study uses literature in the field of social security, legal acts, mass statistics data, and statistical data of KRUS and ZUS. Descriptive and financial analysis methods were used. The results of the study were presented using the tabular method.

Results: As a result of the analysis, it was found that currently the income adequacy of old-age pension insurance in Poland is about 50%. It is much lower than what is considered optimal, which is estimated at 70%. The share of subsidies for old-age pension insurance in budget expenditure in Poland is growing and in 2018 this ratio was 16.16%.

Conclusions: The efficiency of saving in old-age pension insurance in KRUS is over 6 times higher than the efficiency of old-age pension saving in ZUS.
Examination of Satisfaction Level of Bank Service Customers Using Servqual Model
Authors: Zimonjić Velida 
Published: October 2019

Abstract
Customers, their needs, wishes and expectations have to be in the focus of each market-oriented enterprise, whose aim is to survive and develop in the conditions of continuous changes of environment and pronounced degree of competence. The aim of this paper is to emphasise the importance of customer satisfaction linked to service quality using theoretical survey and empirical research, point to factors that influence its level and present the measurement models in order to provide adequate reaction of the enterprise. Special attention is paid to the examination of relationship between the customer satisfaction, expectations, loyalty and service quality. The establishment and maintenance of long-term relationships based on high level of satisfaction through delivery of superior service quality leads to customer loyalty, whereby loyalty is a precondition for repurchase and realisation of business success of an enterprise. Since banking sector is extremely turbulent and characterised by strong competition, the empirical research conducted by the author using SERVQUAL model is aimed at examination of the satisfaction level of bank service customers and consequently making relevant recommendations and conclusions.
Discriminant Analysis - Useful Tool for Predicting Demand in Serbian Motels
Authors: Pavić Lazar , Veljković Božidar , Sešel Bojan 
Published: October 2019

Abstract
In this paper, a discriminant analysis, as useful tool to predict potential demand in Serbian motels, is presented. Through the presented literature review, it was determined that there is not a large number of surveys dealing with the needs and demand of transit tourists. Despite that, transit tourism is one of the priority forms of tourism for the Republic of Serbia in accordance with the established Tourism Development Strategy for the Republic of Serbia for the current period. Questionnaire survey as the main method for data collection is used. According to the results, 14 dimensions of potential guests’ expectations are extracted. The results of discriminant function analysis (DFA) present the impact of potential motel guests’ expectations on the main reason for travelling, while the results of canonical varieties analysis (CVA) present the impact of potential motel guests’ expectations on preferred services in Serbian motels.
Multiple Breakpoint Test on Crude Oil Price
Authors: Phoong Seuk Wai , Phoong Seuk Yen , Moghavvemi Sedigheh , Phoong Kok Hau 
Published: October 2019

Abstract
The impact of structural changes as well as breaks on oil price fluctuations is studied in this article. There are a few channels, such as domestic prices and inflation, that cause the effect of oil price to pass through the economy. The higher crude oil price is immediately followed by the increase in oil products such as gasoline and heating oil. The direct effects continue as people choose alternative energy sources, leading to the increase in price. Besides, the indirect effect on inflation as a result of the behavioral responses of the firms and workers which is known as the “second round” effects in which higher wages is being demanded. This article uses exploratory data analysis to discover the patterns of the variables’ series and then examines the relationship between oil price and consumer price index. Multiple breakpoint test is thereafter used to identify the structural changes in time-varying variables.
The Effect of Dialysis Modality and Membrane Performance on Native Immunity in Dialysis Patients
Authors: Efthymios Pappas M. , Spiridoula Mpournaka , Periklis Katopodis , Andreas Chardalias , Sotiris Tsakas , Theodoros Eleftheriadis , Evangelos Papachristou , Konstantinos Katopodis P. , Dimitrios Goumenos S. 
Published: October 2019

Abstract
Chronic Kidney Disease (CKD) is characterized by immune activation with development of chronic inflammation. However, immune deficiency also exists in CKD patients. The number and the activity of Natural Killer cells (NK-cells) are influenced by the biocompatibility of various dialysis membranes. In this study we investigated the effect of dialysis modality and membrane type on NK-cell number and on phagocytic activity of neutrophils in patients on different dialysis methods.
Sixty patients were included in the study and divided in three groups of 20 patients each. Patients on conventional hemodialysis using Low Flux membrane (cHD-LF) were included in Group I, patients on conventional dialysis using High Flux membrane (cHD-HF) were included in Group II and patients treated by on-line hemodiafiltration with High Flux polysulphone membrane (on-line HDF) were included in Group III. Native immunity was investigated using the number of NK-cells and the phagocytic activity of neutrophils.
NK-cells count was significantly lower (p<0.001) in the three groups of dialyzed patients in comparison to healthy subjects. However, no significant difference was observed in the NK-cells count among patients treated by conventional dialysis using Low or High Flux membrane and patients treated by on-line hemodiafiltration. Similarly, although the phagocytic activity of neutrophils was significantly decreased in all patients on dialysis (p<0.001), no difference related to the dialysis modality or membrane performance was observed. A strong positive correlation was recognized between parathormone blood levels and number of NK-cells (r=0.305, p<0.01).
In conclusion, an impairment of the native immunity represented by NK cell number and phagocytic activity of neutrophils is observed in patients on dialysis. Dialysis modality and membrane performance do not influence the native immunity of dialyzed patients. However, parathormone blood levels are possibly involved in the development of immune system disturbances in such patients.