bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low-Grade Inflammation in the Association between Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis: A Study of More Than 115000 Individuals from the General Population
Authors: Hansen Signe E J , Madsen Christian M , Varbo Anette , Nordestgaard Børge G 
Published: December 2018

Abstract

BACKGROUND
How mild-to-moderate hypertriglyceridemia (2–10 mmol/L; 177–886 mg/dL) potentially causes acute pancreatitis is unknown; however, cellular studies indicate that inflammation might be a driver of disease progression. We tested the hypotheses that (a) mild-to-moderate hypertriglyceridemia is associated with low-grade inflammation and that (b) the association between mild-to-moderate hypertriglyceridemia and risk of acute pancreatitis depends on low-grade inflammation.

METHODS
From the Copenhagen General Population Study and the Copenhagen City Heart Study, 117865 men and women 20–100+ years of age with measurements of nonfasting plasma triglycerides at baseline were followed prospectively for development of acute pancreatitis.

RESULTS
After multivariable adjustment, a 1 mmol/L (89 mg/dL) higher nonfasting triglyceride concentration was associated with 17% (95% CI, 16%–18%, P = 3 × 10−17) higher plasma C-reactive protein (CRP) and a 4.2% (4.0%–4.4%, P = 6 × 10−17) higher blood leukocyte count. Higher concentrations of nonfasting triglycerides were associated almost linearly with higher risk of acute pancreatitis (P for trend = 5 × 10−6), with hazard ratios of 1.5 (95% CI, 0.9–2.5), 2.0 (95% CI, 1.1–3.6), 2.2 (95% CI, 1.0–4.7), 4.2 (95% CI, 1.6–11.5), and 7.7 (95% CI, 3.0–19.8) in individuals with nonfasting triglycerides of 1.00–1.99 mmol/L (89–176 mg/dL; 46% of the population), 2.00–2.99 mmol/L (177–265 mg/dL; 17%), 3.00–3.99 mmol/L (266–353 mg/dL; 6%), 4.00–4.99 mmol/L (354–442 mg/dL; 2%), and ≥5mmol/L(443 mg/dL; 2%), respectively, vs individuals with &lt;1 mmol/L (89 mg/dL; 27%). The association with risk of acute pancreatitis appeared more pronounced in individuals with CRP of ≥1.39 mg/L (P for trend = 0.001) and leukocytes of ≥7 × 109/L (P = 2 × 10−4) than in those with CRP &lt;1.39 mg/L (P = 0.03) and leukocytes &lt;7 × 109/L (P = 0.04); however, there was no formal evidence of statistical interaction (P = 0.38 for CRP and P = 0.41 for leukocytes).

CONCLUSIONS
Mild-to-moderate hypertriglyceridemia is associated with low-grade inflammation and higher risk of acute pancreatitis. The association between mild-to-moderate hypertriglyceridemia and risk of acute pancreatitis is possibly partly mediated by low-grade inflammation.
INTERFERENSI FONETIS BAHASA ARAB DALAM BAHASA INDONESIA: ANALISIS UJARAN BAHASA INDONESIA OLEH PENUTUR ARAB
Authors: Nasaruddin Nasaruddin 
Published: December 2018

This article aims to analyze the forms of phonetic interference of Arabic language in the Indonesian language speech spoken by an Arabic native speaker. The source of the data and the object of analysis in this article are the recordings of religious lectures of a preacher from Madinah, Saudi Arabia, Sheikh Ali Jabir, which have been delivered in Indonesian language and widely circulated on YouTube site. The lecture recordings are positioned as Indonesian speech events delivered by an Arabic native speaker. The analytical frameworks used in this paper are the theory of the first language interference over the second language, the theory of contrastive analysis, and the theory of error analysis. The interference theory is applied to understand the flow and the form of interference between Arabic and Indonesian language. The contrastive analysis is applied to identify the phonemic differences between Arabic and the Language of Indonesia and to predict the interferences they cause. Meanwhile, the error analysis is applied to identify the forms of phonetic interference of Arabic over the Indonesian language and to explain their causes and motives. This research finds that there are forms of interference of Arabic sounds in Indonesian speeches spoken by an Arabic native speaker which can generally be patterned in two forms, namely, changes in the pronunciation of unknown Indonesian sounds in Arabic, and changes in the pronunciation of the sounds of the Indonesian words derived from the Arabic language. Both of these two patterns are marked by the change of point and manner of articulation of some Indonesian sounds.
Does wind speed and direction influence timing and route of a trans-hemispheric migratory songbird (purple martin) at a migration barrier?
Authors: Abdulle S. A. , Fraser K. C. 
Published: December 2018

Abstract
The influence of weather on the departure decisions and routes of migratory birds can now be further investigated with the use of direct tracking methods. We tested hypotheses for migration departure decisions and flight trajectories by determining the influence of wind speed and direction at the Yucatan peninsula in spring on departure date, migratory route, and longitude of arrival at the northern Gulf coast of a trans-hemispheric migratory songbird, purple martin (Progne subis). Birds were equipped with geolocators at their breeding colony and 36 were recaptured upon return after spring migration. While southerly tailwinds with low wind speeds prevailed at the Yucatan during the period of passage, we found that daily wind speed and direction were still important predictors of departure date. However, wind conditions at departure did not predict longitude of arrival at the US gulf coast after crossing the gulf. Birds appeared to favour the shortest distance across the Gulf of Mexico, aided by consistent tailwinds, but may have corrected for wind drift so as to land at a longitude near 88°, reflecting the shortest distance across from the Yucatan staging areas. Considering their use prior to departure, high quality roost sites at the Yucatan peninsula would be important conservation targets for this declining aerial insectivore.
Lern- und kompetenzförderliche Arbeitsgestaltung in der digitalisierten Arbeitswelt
Authors: Dehnbostel Peter 
Published: December 2018

ZusammenfassungKonzepte und Kriterien der lernförderlichen Gestaltung von Arbeit sind seit den 1970er-Jahren Gegenstand von Forschung und Entwicklung verschiedener Disziplinen. Heute ist die Arbeitsgestaltung nicht nur lernförderlich, sondern lern- und kompetenzförderlich auszurichten. Sie bezieht sich auf eine zunehmend digitalisierte Arbeit, die unter dem Label „Industrie 4.0“ die Entwicklung von Arbeit und Arbeitsstrukturen dominiert. Dabei wird arbeitsintegriertes Lernen zu einem konstitutiven Bestandteil digitalisierter Arbeit. Arbeits- und Lernorte werden entgrenzt, zugleich um die Arbeit gestaltende Lernräume, Lernarchitekturen und Lernformen erweitert. Unter Bezug darauf werden bestehende Dimensionen und Merkmale der Arbeitsgestaltung als übergreifende Kriterien fortgeschrieben, die gleichermaßen der Analyse wie der Konstruktion lern- und kompetenzförderlicher Arbeitsgestaltung dienen.
Führung unter lernförderlichen Arbeitsbedingungen
Authors: Elbe Martin 
Published: December 2018

ZusammenfassungArbeit und Führung befinden sich in einem weltweiten Wandlungsprozess, der Menschen ebenso wie maschinelle Systeme betrifft. Lernprozesse und Lernverantwortung werden zunehmend integrale Bestandteile von Arbeits- und Führungsanforderungen. Dabei erfolgt Lernen in autonomen Raum-Zeit-Arrangements, was für menschliche Arbeitende nach wie vor als Ausnahme erscheint. Einsatzorganisationen als Lern- und Arbeitsraum liefern hier ein Beispiel für die Verknüpfung von Arbeit, Führung und Lernen hin zu einer integrierten Lern- und Führungskultur. Dies wird im vorliegenden Beitrag als theoretischer Entwurf aufgrund empirischer Analyseergebnisse entwickelt.
Characteristics of small-sized space debris objects detected at the Terskol observatory in 2016-2017
Authors: Levkina Polina , Bakhtigaraev Nail , Martynyuk-Lototskyy Konstantin , Velichko Sergey , Sokolov Ilia , Bondar Arkadii , Khorunzhiy Pavel , Chazov Vadim 
Published: December 2018

Abstract
The study of near-Earth space includes the detection and investigation of an increasing number of space debris objects by ground-based optical telescopes. There is no natural cleansing of space in the geostationary region. The telescope Zeiss-2000 with a two-meter aperture of the Terskol observatory is the largest optical instrument regularly used for space debris investigations. One of the main purposes in «Astronomy in the Elbrus region» international program’s boundaries is the detection and characterization of small fragments of debris,which are invisible for smaller telescopes. During observations on photometric nights we usually detect 4-5 unknown fragments of 17-21st star magnitude. In this article, we present orbital parameters and physical characteristics of several small-sized fragments of the space debris detected at the Terskol observatory in 2016-2017.
Profits Under Centralized Negotiations: The Efficient Bargaining Case
Authors: Buccella Domenico , Fanti Luciano 
Published: December 2018

AbstractMaking use of a Conjectural Variation model, the present note re-examines the subject of the firms’ profits ranking under different degrees of market competition in a unionized duopoly with industry-wide Efficient Bargaining (EB). It is shown that, while Cournot-like competition profits are always larger than Bertrand-like ones with separated wage negotiations, an uniform wage bargaining can lead to the appearance of the reversal.
Adapting Open-space Learning Techniques to Teach Cultural Literacy
Authors: Ochoa Gabriel García , McDonald Sarah , Monk Nicholas 
Published: December 2018

Abstract
There is a growing body of work on the theory of cultural literacy, but little has been written on how to teach cultural literacy in higher education contexts. This article discusses the use of Open-space Learning (OSL) techniques as valuable tools for teaching cultural literacy. Cultural literacy and OSL are two different areas of study, but there is common ground between them, and cultural literacy can draw great benefit from the cross-pollination of ideas with OSL. The paper focuses on practice-based models used in OSL that have been adapted to teach cultural literacy. The aim of these practice-based models is to create an environment that teaches students how to transfer the analytical and critical skills that they learn as part of a literary and cultural studies (LCS) course to real-life scenarios. We argue that an important part of this learning environment is what we refer to as cognitive “destabilisation,” and discuss why OSL techniques are ideally suited to fostering such destabilisation in students.
Lossy Media: Queer Encounters with Infrastructure
Authors: Payne Robert 
Published: December 2018

Abstract
In an era of “frictionless” digital environments, this article proposes a queer analysis of the “lossy” materialities of mediated encounters. Building on recent scholarship on media failure and media infrastructures, it will argue that moments of disruption and deterioration commonly experienced by users reveal the failure of overlapping social and technical infrastructures to ensure lossless transmission of normative fantasies of subjectivity and mediated relationality. Highlighting the queer instability of material assemblages, it will pay close attention to how the articulation of bodies, objects, and spaces in particular scenes of lossy encounter generates unplanned affective intensities which may disorient and undo the consuming subject. Borrowing the concept of lossy file compression and adapting it for this purpose, the article’s broad aim is to offer a queer critical framework for inhabiting the contingent, emergent, and dissipating energies of media encounters beyond the capital-driven instrumentalisation of agency and the neoliberal imperatives of update culture.
Ovarian reserve in adolescent girls born prematurely
Authors: Elgina Svetlana , Artymuk Natalia , Nikulina Elena 
Published: December 2018

Abstract

Background
The objective was to estimate ovarian reserve in adolescent girls born prematurely.

Materials and methods
Two hundred adolescent girls aged 15–16 years who were born prematurely and full term were studied with laboratory, ultrasound and statistical methods.

Results
Statistically significant differences of the main parameters that characterize ovarian reserve in adolescent girls born prematurely compared to those born full term were specified. The levels of estradiol (p = 0.027), anti-Müllerian hormone (p = 0.0004) and inhibin В (p = 0.015) were lower in the girls born prematurely and follicle stimulating (p = 0.0001) and lutenizing (p = 0.002) hormone levels were higher. The ultrasound imaging (USI) findings of the uterus and appendages were also different. Adolescent girls born prematurely had longer uterus cervix, smaller sizes of endometrial echo, smaller ovarian sizes and fewer follicles in them.

Conclusions
Adolescent girls born prematurely have different parameters of ovarian reserve compared to those of girls born full term.
Numerical solution of a source identification problem: Almost coercivity
Authors: Ashyralyev Allaberen , Erdogan Abdullah Said , Sazaklioglu Ali Ugur 
Published: December 2018

Abstract
The present paper is devoted to the investigation of a source identification problem that describes the flow in capillaries in the case when an unknown pressure acts on the system. First and second order of accuracy difference schemes are presented for the numerical solution of this problem. Almost coercive stability estimates for these difference schemes are
established. Additionally, some numerical results are provided by testing the proposed methods on an example.
Status and trends in the use of insulin analogs, insulin delivery systems and their association with glycemic control: comparison of the two consecutive recent cohorts of Japanese children and adolescents with type 1 diabetes mellitus
Authors: Yamamoto Yukiyo , Kikuchi Toru , Urakami Tatsuhiko , Goto Motohide , Tsubouchi Kohji , Sasaki Goro , Mizuno Haruo , Abe Yuki , Kitsuda Kazuteru , Amemiya Shin , Sugihara Shigetaka 
Published: December 2018

AbstractBackgroundTreatment for type 1 diabetes mellitus (T1DM) has greatly changed by the general use of insulin analogs and continuous subcutaneous insulin infusion (CSII). To investigate whether these advances have been translated into continued improvement in glycemic control in Japanese children and adolescents, we analyzed the registration data of the two consecutive recent cohorts of Japanese childhood-onset T1DM patients.MethodsThe registration data including hemoglobin A1c(HbA1c), hypoglycemia and insulin regimen were compared between the two cohorts (862 patients in the 2008 cohort and 1090 in the 2013 cohort).ResultsThe proportion of subjects with multiple daily insulin injection therapy (MDI) and CSII significantly increased (p<0.0001) from 67.4% and 9.7% to 71.8% and 23.4%, respectively. In the 2013 cohort, almost all patients were treated with basal-bolus treatment using insulin analogs. The use of CSII increased in all age groups, especially in the age group 0–5 years. The rates of overall, moderate and severe hypoglycemia significantly declined from 10.24, 10.18 and 0.056 events/100 persons/period in the 2008 cohort to 0.66, 0.62 and 0.033 in the 2013 cohort (p<0.0001, <0.0001, 0.04), respectively. Contrarily, there were no significant changes in HbA1cvalues between the two cohorts.ConclusionsThe popularization of the basal-bolus treatment using insulin analogs hascontributed to a significant decrease in hypoglycemia. In contrast, the intensive insulin treatment may not be enough for the satisfactory improvement of glycemic control in Japanese children and adolescents with T1DM. Considerable points remain, such as diabetic education and support to motivate patients.
Digital Demodulator of the Quadrature Amplitude Modulation Signals
Authors: Chernoyarov Oleg , Glushkov Alexey , Litvinenko Vladimir , Litvinenko Yuliya , Matveev Boris 
Published: December 2018

Abstract
In this paper, the digital algorithm and the device for the demodulation of the quadrature amplitude modulation signals are considered. The fundamental advantages of our approach are simple hardware implementation, minimal number of arithmetic operations required over the signal period as well as the potential interference immunity in the presence of Gaussian noise. The expressions have been found for the error probability and their inaccuracy has been estimated. By means of the statistical simulation methods, the practical interference immunity of the introduced demodulator, together with the influence of phase locking errors have been tested. The introduced demodulator can be implemented either as a device independent from the programmable logic devices, or as an installation unit of the receiver equipment.
Crystal structure of N′-((1E,2E)-4-(7-methoxy-2-oxo-2H-chromen-8-yl)-2-methylbut-2-en-1-ylidene)-4-methylbenzenesulfonohydrazide, C22H22O5N2S
Authors: Yu Xiang , Qin Yan , Yan Jing , Chen Ya-Fang 
Published: December 2018

Abstract
C22H22O5N2S, monoclinic, P21/n (no. 14), a = 8.1080(2) Å, b = 14.4763(4) Å, c = 18.2819(5) Å, β = 95.270(3)°, V = 2136.75(10) Å3, Z = 4, R
gt(F) = 0.0488, wR
ref(F
2) = 0.1220, T = 291 K.
Analysis of the Imaging Characteristics of the KB and KBA X-ray Microscopes at Non-coaxial Grazing Incidence
Authors: Lingling Zhao , Knepper Jon 
Published: December 2018

AbstractIn the last 20 years, requirements for x-ray lithography, space technology and ICF process diagnosis, the x-ray imaging technology has been developed. However, x-ray imaging turns out to be more difficult due to intense absorption of x-rays, and the refractive index of x band is slightly less than 1. Normal imaging method may not be suitable for x-ray band. At present, grazing reflective imaging and coded aperture imaging are commonly used for this band. This paper presents a detailed analysis of the imaging characteristics of single-mirror and double-mirror. Then the focal distance, field obliquity and aperture position of the mirrors of the KBA microscopes at grazing incidence are studied. The results show that the structure arrangement of the KBA microscope is rather reasonable, and can be considered as theoretical evidence in the design and manufacture of KBA microscopes.
Radiation Shielding Investigation of Lead Borophosphate Glasses Modified by Tungsten Oxide
Authors: Sayyed M. I. , Almatari M. 
Published: December 2018

Abstract
The effect of tungsten trioxide (WO3) on the shielding properties of the lead(II) oxide–boron trioxide–phosphorus pentoxide–WO3 system was investigated. The mass attenuation coefficients (μ/ρ) were evaluated using the XCOM program (National Institute of Standards and Technology, Gaithersburg, MD) in the energy range of 0.015–10 MeV. The μ/ρ values were then used to calculate the mean free path (MFP) and half value layer (HVL). In addition, the macroscopic effective removal cross section for fast neutrons (ΣR) was calculated for the present glass system. It was found that the μ/ρ values increase with increasing WO3 concentration, while HVL and MFP values decrease with increasing WO3 content. The present glass system showed good radiation shielding properties by providing shorter MFP than some glass systems, such as 70TeO2-30V2O5 and 80TeO2-20MoO3 glasses. In addition, it was found that the ΣR values for the present glasses lie within the range of 0.1100–0.1132 cm−1.
Coupling of Human Rhodopsin to a Yeast Signaling Pathway Enables Characterization of Mutations Associated with Retinal Disease
Authors: Scott Benjamin M , Chen Steven K , Bhattacharyya Nihar , Moalim Abdiwahab Y , Plotnikov Sergey V , Heon Elise , Peisajovich Sergio G , Chang Belinda S W 
Published: December 2018

AbstractG protein-coupled receptors (GPCRs) are crucial sensors of extracellular signals in eukaryotes, and direct measurement of GPCR-mediated signaling is useful for high-throughput mutational studies. However, this is particularly difficult for the light-activated GPCR rhodopsin...G protein-coupled receptors (GPCRs) are crucial sensors of extracellular signals in eukaryotes, with multiple GPCR mutations linked to human diseases. With the growing number of sequenced human genomes, determining the pathogenicity of a mutation is challenging, but can be aided by a direct measurement of GPCR-mediated signaling. This is particularly difficult for the visual pigment rhodopsin—a GPCR activated by light—for which hundreds of mutations have been linked to inherited degenerative retinal diseases such as retinitis pigmentosa. In this study, we successfully engineered, for the first time, activation by human rhodopsin of the yeast mating pathway, resulting in signaling via a fluorescent reporter. We combine this novel assay for rhodopsin light-dependent activation with studies of subcellular localization, and the upregulation of the unfolded protein response in response to misfolded rhodopsin protein. We use these assays to characterize a panel of rhodopsin mutations with known molecular phenotypes, finding that rhodopsin maintains a similar molecular phenotype in yeast, with some interesting differences. Furthermore, we compare our assays in yeast with clinical phenotypes from patients with novel disease-linked mutations. We demonstrate that our engineered yeast strain can be useful in rhodopsin mutant classification, and in helping to determine the molecular mechanisms underlying their pathogenicity. This approach may also be applied to better understand the clinical relevance of other human GPCR mutations, furthering the use of yeast as a tool for investigating molecular mechanisms relevant to human disease.
Potensi Penggunaan Tempurung Kelapa sebagai Adsorben Ion Logam Fe(III)
Authors: Mastiani Neng , Amalia Vina , Rosahdi Tina Dewi 
Published: December 2018

Besi merupakan logam yang paling banyak sekali ditemui dalam kehidupan sehari-hari. Kandungan besi berlebihan di dalam air dapat menyebabkan bekas karat pada pakaian, porselin dan dalam jumlah yang tinggi dapat bersifat sebagai racun bagi tubuh. Pada penelitian ini dipelajari potensi penggunaan tempurung kelapa sebagai adsorben ion logam Fe(III). Adsorben dari bahan tempurung kelapa disiapkan pada berbagai metode perlakuan awal, yaitu (1) tanpa perlakuan; (2) tanpa lignin (delignisasi); (3) diarangkan; (4) dikalsinasi pada suhu 400°C; dan (5) dikalsinasi pada suhu 600°C. Selanjutnya dari masing-masing perlakuan dibagi menjadi dua bagian untuk diaktivasi dan tidak diaktivasi dengan aktivator yang digunakan yaitu NaOH. Konsentrasi ion logam Fe(III) setelah adsorpsi dianalisis menggunakan AAS. Hasil penelitian menunjukkan perlakuan yang paling efektif dalam menurunkan konsentrasi logam yaitu pada suhu 600oC, tanpa aktivasi dengan efisiensi 100% dan kapasitas adsorpsi sebesar 0,93 mg/g. Berdasarkan hasil penelitian tempurung kelapa efektif digunakan sebagai adsorben untuk penurunan logam besi pada larutan Fe(III) dari konsentrasi awal sebesar 10 ppm menjadi 0 ppm maka ion logam Fe pada larutan Fe(III) 10 ppm sudah terserap oleh adsorben tempurung kelapa.