bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thrombotic Complications in Gliomas
Authors: Czap Alexandra L. , Becker Ashley , Wen Patrick Y. 
Published: April 2019

AbstractArterial and venous thromboses are common in glioma patients, both in the perioperative period and throughout the course of the disease. High-grade glioma patients harbor underlying hypercoagulability, which predisposes these high-risk patients with prolonged immobility and neurologic deficits to thrombotic events. Despite the high incidence and recurrent nature of these complications, there is no standardized approach to the management of glioma patients, and many challenges remain. Historically, the perceived risk of intracranial and intratumoral hemorrhage limited the use of anticoagulation, favoring nonpharmacological prophylaxis and treatment. Multiple studies have demonstrated the safety and efficacy of anticoagulation when indicated, with low molecular weight heparin as the preferred short- or long-term treatment. This review will discuss the epidemiology, risk factors, and therapeutic management of both venous and arterial thrombotic complications in glioma.
Vitamin D deficiency and benign paroxysmal positioning vertigo
Authors: Carneiro de Sousa Pedro Jorge Matos , Abreu Pereira Diogo Manuel , Carneiro Melo Pereira de Magalhães Pedro , Duarte Delfim Rui da Silva , Trigueiros da Silva Cunha Nuno Maria 
Published: April 2019

Objectives:
Benign paroxysmal positioning vertigo (BPPV) has significant recurrence rates, mainly in older patients. The etiopathology of recurrent BPPV is possibly related to low serum vitamin D levels. Finding a therapeutic weapon will help with these complicated cases, reducing disability, falling risk and also health care costs.

Study design:

Clinical trial: one-year duration.

Setting:
Ten patients with diagnosis of BPPV made by history and physical examination and at least two episodes of documented BPPV in the previous two years and chronic complaints of dizziness. Neurologic and other otological diseases were excluded for these patients.

Subjects and methods:
Vitamin D was evaluated by measuring serum 25-hydroxyvitamin D (25-OHD). Levels below 20 ng/mL were considered deficiency and levels between 20 and 30 ng/mL were considered insufficiency. Half of the patients (treatment group) started a treatment with cholecalciferol while the remaining patients were the control group. All of the patients were reevaluated every three months.

Results:
All patients of the treatment group did not have any subsequent episode of positional vertigo, dizziness complaints or nystagmus evoked by provocative manoeuvers. At reevaluations, the mean value of serum 25-OHD for the treatment group had increased noticeably. It was also significantly higher than the mean value of control group. All patients of control group had positional vertigo episodes, as well as positional nystagmus at office reevaluations.

Conclusion:
These results support the need to systematically measure and correct vitamin D levels in patients with recurrent BPPV.
Strong seedling recruitment does not limit mangrove vulnerability to harvest
Authors: Gaoue Orou G , Yessoufou Kowiyou 
Published: April 2019

AbstractEcological studies on the impacts of timber harvesting contributed to inform sustainable management strategies of tropical forests. However, these studies rely strongly on two major assumptions: (i) strong seedlings recruitment predispose for positive population dynamics, and (ii) more adult trees is a guarantee for a strong reproductive capability of the population. These assumptions are applied without accounting for the life history of the harvested species. Here, we revisit these assumptions in light of the life history theory, which predicts different responses of short- and long-lived species to perturbation. We predict that harvesting adults, rather than reducing seedling recruitment of long-lived species, would have greater impact on population dynamics. We tested our prediction on three mangrove species in South Africa. First, we reconstructed the projection matrices for three mangrove species in the Mngazana Estuary of Eastern Cape province of South Africa. Next, we simulated a range of harvest intensities for different life stages and explored how harvesting influences population dynamics. Finally, we examined the age-specific mortality trajectories for all three species. We found that populations of all three species were closer to their stable stage distribution. Contrary to popular belief, we found that changes in seedling recruitment will have minimal effects on mangrove long-term population dynamics, a finding consistent with the life history theory. However, contrary to expectation, simulating harvest of adults had minimal effect on population dynamics. This is due to low reproductive values for these late stages. Our analysis of age-specific mortality trajectories further provided evidence for positive senescence particularly forAvicenniawhich was the least resilient to harvest. Our findings cast doubt on the traditional forest management strategies that rely strongly on seedling density as a metric of sustainability and forbid unquestionably harvesting large individuals. We call for caution while generalizing forest management strategies irrespective of the life history of the species at hand.
Evaluation of eddy current damper for vibration control of a frame structure
Authors: Ao Wai Kei , Reynolds Paul 
Published: April 2019

Abstract
In this study, an eddy current damper (ECD) prototype model is presented. The ECD consists of three principal components: Neodymium Iron Boron (NdFeB) permanent magnets, a copper plate (conductive material) and an aluminium frame. The magnets have a rectangular design, and can be assembled with magnetic pole projection in either alternative or unidirectional orientations and in two orthogonal directions. The key merit of this type of ECD is its non-contact characteristic; thus there is a complete absence of mechanical friction. This study examines the use of this prototype damper when applied to suppress structural vibration in multi-storey frame structure. To effectively estimate the damping performance of the ECD, simple analytical calculations involving both infinite and finite boundaries are proposed and illustrated in this paper. These can be compared against the results of more sophisticated finite element analysis (FEA). The conductive material can be defined to move in two orthogonal directions. Therefore, based on the four magnet configurations and two directions of motion of conductive material, a total of eight models were created for analysis and validated by the proposed designed formule. It was found that analysis based on the method of images provides a satisfactory estimation of the damping force, similar to that estimated using the FE model. This study also includes experimental testing of a prototype ECD applied to suppress vibration within a six-storey aluminium frame structure. This testing shows that the prototype ECD is able to provide a significant level of damping with performance comparable to that of an ideal conventional linear viscous damper.
Non-classical correlations in reducible quantum electrodynamics
Authors: Naudts Jan 
Published: April 2019

Abstract
The question is discussed whether the momentum of a photon has a quantum uncertainty or whether it is a classical quantity. The latter assumption is the main characteristic of reducible Quantum Electrodynamics (QED). Recent experiments in Quantum Optics may resolve the question. The non-classical correlation of quantum noise in color-entangled beams cannot be explained by reducible QED without modification of the standing explanation. On the other hand, reducible QED explains uncertainty of the momentum of a single photon when it is entangled with a quantum spin residing in its environment. The explanation of the historical experiment with equally-polarized pairs of photons, showing violation of the Bell inequalities, invokes the argument of collapse of the wave function, also in reducible QED.
G-CSF-mobilized peripheral blood mononuclear cells combined with platelet-rich plasma accelerate restoration of ovarian function in cyclophosphamide-induced POI rats†
Authors: Huang Qiuyan , Liu Bo , Jiang Rufang , Liao Shengbin , Wei Zhiyao , Bi Yin , Liu Xueyuan , Deng Rong , Jin Yufu , Tan Ying , Yang Yihua , Qin Aiping 
Published: April 2019

Abstract
Peripheral blood mononuclear cells (PBMCs) are rich in hematopoietic cells and mesenchymal stem cells. Platelet-rich plasma (PRP) is rich in various growth factors. PBMCs and PRP have been suggested, individually, to restore ovarian function by improving the local microenvironment. The current study investigated the effect of granulocyte colony-stimulating factor (G-CSF)-mobilized PBMCs combined with PRP on restoring ovarian function in rats with primary ovarian insufficiency (POI). Thirty adult female rats were randomly subdivided into five groups: normal control (control), cyclophosphamide (CTX) plus subsequent PBS (POI + PBS), CTX plus subsequent PRP (POI + PRP), CTX plus subsequent G-CSF-mobilized PBMCs (POI + PBMCs), and CTX plus subsequent G-CSF-mobilized PBMCs combined with PRP (POI + PBMCs + PRP). CTX exposure induced the typical POI phenotype with increased diestrus; shortened estrus; follicle arrest at all stages; decreased serum levels of estradiol-17β (E2) and anti-Mullerian hormone (AMH); and increased levels of follicle-stimulating hormone (FSH). Transplantation of mobilized PBMCs with PRP resulted in a much earlier restoration of the estrous cycle, sex hormone levels, and preantral follicle growth in POI rats. Expression of the male-specific Sry gene in the ovarian tissues of POI + PBMCs + PRP female recipient rats was evident at 5, 10, and 20 days posttransplantation along with significant increases in the expression of angiogenesis markers CD34+ and VEGF and folliculogenesis markers AMH and FSHR. Additionally, PBMCs in combination with PRP mitigated granulosa cell apoptosis by downregulating BAX and upregulating BCL-2. These results demonstrate that G-CSF-mobilized PBMCs combined with PRP accelerate the restoration of ovarian function in POI rats by increasing ovarian neovascularization, reducing granulosa cell apoptosis, and promoting folliculogenesis.
The Pleasure Principle of Magic Mike XXL: Sonic Visibility Toward Female Audiences
Authors: Warner Kristen J 
Published: April 2019

AbstractA key difference between Magic Mike (2012) and Magic Mike XXL (MMXL, 2015) is the latter films narrative shift toward the viewing experience of its targeted female audience. The hyper-lean storyline that streamlined all the indulgences of Steven Soderbergh’s original transformed the franchise into a spectacle for women. The goal of this article, then, is to examine how MMXXL’s sonic and visual structures create the resonance that then translates to pleasure and a more holistic kind of representation for female viewers. By exploring how this film deploys not only the visual cues of beautiful male bodies to create bodily responses in its largely female audience but also querying how the sound cues create sonic visibility, I aim to illustrate how MMXXL enables women viewers from a cross section of intersectional identities the opportunity to not only feel seen but also desired.
Human leucocyte antigen-associated anti-glomerular basement membrane disease in siblings
Authors: Durcan Martin E , Nair Beena , Anderton John G 
Published: April 2019

Abstract
We report a case of anti-glomerular basement membrane (GBM) disease in association with human leucocyte antigen (HLA) DRB1 15:01. A 71-year-old woman presented with oligoanuric acute kidney injury accompanied by high titre anti-GBM antibodies. Renal biopsy revealed a severe crescentic glomerulonephritis. Her brother had presented 6 years earlier with oligoanuric acute kidney injury. He was dual positive for MPO ANCA and anti-GBM antibodies. Renal biopsy was not performed. Both had an absence of pulmonary involvement. Tissue typing confirmed both were heterozygous for HLA DRB1 15:01 and DRB1 04:03.
Conceptualizing, Organizing, and Positing Moderation in Communication Research
Authors: Holbert R Lance , Park Esul 
Published: April 2019

Abstract
Meta-theoretical focus is given to how communication researchers are approaching and hypothesizing moderation. A moderation typology is offered and an evaluation of the field’s common practices for positing moderation reveals an inability to discern between three overarching classifications (Contributory, Contingent, Cleaved). A content analysis of eight communication journals reveals moderation hypotheses lacking a level of precision that can best aid the field’s knowledge generation. In addition, vague hypothesizing is leaving communication researchers vulnerable to the commitment of Type III error (i.e., correctly rejecting a null hypothesis for the wrong reason). Recommendations are provided in an effort to improve the field’s conceptualization and presentation of moderation.
Algorithmic Personalization and the Two-Step Flow of Communication
Authors: Soffer Oren 
Published: April 2019

Abstract
This study examines the relevance of traditional mass communication’s two-step flow-of-communication theory in relation to algorithmic personalization. I compare the two-step flow theory’s concept of personalized content through opinion leaders with the current notion of personalized algorithms, arguing that opinion leaders and algorithms both function as gatekeeping agents. I also discuss the nature and role of peer groups in the two cases, arguing that while in the original theory, groups were seen as relatively solid (family, friends, and work colleagues), groups in the algorithmic era are much more liquid, transforming according to data inputs and users’ behavior. Finally, the article also considers differences in the source of authority of opinion leaders and algorithms in both eras, as well as the different social settings and public awareness in the second step of the communication flow.
Dryland Organic Farming Partially Offsets Negative Effects of Highly Simplified Agricultural Landscapes on Forbs, Bees, and Bee–Flower Networks
Authors: Adhikari Subodh , Burkle Laura A , O’Neill Kevin M , Weaver David K , Delphia Casey M , Menalled Fabian D 
Published: April 2019

AbstractIndustrialized farming practices result in simplified agricultural landscapes, reduced biodiversity, and degraded species-interaction networks. Thus far, most research assessing the combined effects of farming systems and landscape complexity on beneficial insects has been conducted in relatively diversified and mesic systems and may not represent the large-scale, monoculture-based dryland agriculture that dominates many regions worldwide. Specifically, the effects of farming systems on forbs, bees, and their interactions are poorly understood in highly simplified dryland landscapes such as those in the Northern Great Plains, United States, an area globally important for conventional and organic small grain, pulse, forage, and oilseed production. During a 3-yr (2013–2015) study, we assessed 1) the effects of dryland no-till conventional and tilled organic farming on forbs, bees, and bee–flower networks and 2) the relationship between natural habitat and bee abundance. Flower density and richness were greater in tilled organic fields than in no-till conventional fields, and forb community composition differed between farming systems. We observed high bee diversity (109 taxa) in this highly simplified landscape, and bee abundance, richness, and community composition were similar between systems. Compared with tilled organic fields, bee–flower interactions in no-till conventional fields were poorly connected, suggesting these systems maintain relatively impoverished plant-pollinator networks. Natural habitat (11% of the landscape) did not affect small-bodied bee abundance in either farming system but positively affected large-bodied bees within 2,000 m of crop-field centers. In highly simplified agricultural landscapes, dryland organic farming and no-till conventional farming together support relatively high bee diversity, presumably because dryland organic farming enhances floral resources and bee–flower networks, and no-till management in conventional farming provides undisturbed ground-nesting habitats for wild bees (Hymenoptera: Apoidea).
Basal area and diameter growth in high-graded eastern temperate mixedwood forests: the influence of acceptable growing stock, species, competition and climate
Authors: Power Hugues , Raymond Patricia , Prévost Marcel , Roy Vincent , Berninger Frank 
Published: April 2019

AbstractHarvesting practices in temperate mixedwoods of eastern North America have a history of diameter-limit cuts, which have often resulted in degraded residual stands. In this study, we examined the factors influencing stand basal area (BA) and tree diameter growth in previously high-graded mixedwood forests, to understand which stands are more likely to recover from high-grading. Over 15 years, we monitored tree growth, recruitment and stem quality of 532 sample plots that were located in high-graded stands of Quebec’s mixedwood forest. We found that diameter growth rates were positively correlated with precipitation-related variables for balsam fir (Abies balsamea) and for yellow birch (Betulla alleghaniensis) but opposing trends for temperature-related variables were found. Conversely to balsam fir, yellow birch growth was positively correlated to temperature variables. Our results also show that BA growth was greater for plots with a larger acceptable growing stock (AGS: trees with potential sawlog production) and that the increase in AGS was greater for plots with larger amount of conifer BA. These result highlights the importance to maintain a proportion of conifer trees in these mixed stands. Moreover, the significant effect of asymmetric competition in our study underscores the relevance of considering the spatial distribution when choosing crop trees.
Exploring coarse- to fine-scale approaches for mapping and estimating forest volume from Brazilian National Forest Inventory data
Authors: David Hassan C , MacFarlane David W , Péllico Netto Sylvio , Corte Ana Paula Dalla , Piotto Daniel , de Oliveira Yeda M M , Morais Vinicius A , Sanquetta Carlos R , Neto Rorai P M 
Published: April 2019

Abstract
The aim of this study was to explore methods to: (1) enhance coarse-scale estimates of wood volume from National Forest Inventories (NFIs) data and (2) map them at finer scales. The ‘standard’ coarse-scale estimation extrapolates wood volume from clusters to the grid cell they represent, using the cluster’s represented forested area (RFA) to predict the cell’s forested area. Data from a subset of Brazil’s NFI clusters were combined with Landsat-8 imagery to explore a new coarse-scale method, where forested area derived from image classification (FADIC) is used instead of RFA. The RFA- and FADIC-derived estimates of total volume were, respectively, 197.4 million m3 and 116.3 million m3. For fine-scale methods, volume was estimated and mapped at pixel level using: (i) surface reflectance-based models (SRMs), and (ii) regression-kriging (RK) and a RK model (RKM) whose inputs were latitude and longitude of pixels. The SRM-based method captured the mean and the general spatial trend of the volume well. The RK-based method also estimated the mean well, but it failed to predict higher and lower volumes. The SRM- and RK-based estimates of total volume were 211.7 million m3 and 203.3 million m3, an overestimate of 7 per cent and 3 per cent, respectively, of the ‘standard’ NFI estimate (197.4 million m3), though both estimates were within the 95 per cent confidence interval, meaning that both fine-scale methods yield total volume statistically similar to the ‘standard’ coarse-scale method.
Positive Selection Evidence in Xylose-Related Genes Suggests Methylglyoxal Reductase as a Target for the Improvement of Yeasts’ Fermentation in Industry
Authors: Borelli Guilherme , Fiamenghi Mateus Bernabe , dos Santos Leandro Vieira , Carazzolle Marcelo Falsarella , Pereira Gonçalo Amarante Guimarães , José Juliana 
Published: April 2019

AbstractXylose assimilation and fermentation are important traits for second generation ethanol production. However, some genomic features associated with this pentose sugar’s metabolism remain unknown in yeasts. Comparative genomics studies have led to important insights in this field, but we are still far from completely understanding endogenous yeasts’ xylose metabolism. In this work, we carried out a deep evolutionary analysis suited for comparative genomics of xylose-consuming yeasts, searching for of positive selection on genes associated with glucose and xylose metabolism in the xylose-fermenters’ clade. Our investigation detected positive selection fingerprints at this clade not only among sequences of important genes for xylose metabolism, such as xylose reductase and xylitol dehydrogenase, but also in genes expected to undergo neutral evolution, such as the glycolytic gene phosphoglycerate mutase. In addition, we present expansion, positive selection marks, and convergence as evidence supporting the hypothesis that natural selection is shaping the evolution of the little studied methylglyoxal reductases. We propose a metabolic model suggesting that selected codons among these proteins caused a putative change in cofactor preference from NADPH to NADH that alleviates cellular redox imbalance. These findings provide a wider look into pentose metabolism of yeasts and add this previously overlooked piece into the intricate puzzle of oxidative imbalance. Although being extensively discussed in evolutionary works the awareness of selection patterns is recent in biotechnology researches, rendering insights to surpass the reached status quo in many of its subareas.
Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding
Authors: Hanghøj Kristian , Moltke Ida , Andersen Philip Alstrup , Manica Andrea , Korneliussen Thorfinn Sand 
Published: April 2019

Abstract

Background
The estimation of relatedness between pairs of possibly inbred individuals from high-throughput sequencing (HTS) data has previously not been possible for samples where we cannot obtain reliable genotype calls, as in the case of low-coverage data.

Results
We introduce ngsRelateV2, a major revision of ngsRelateV1, a program that originally allowed for estimation of relatedness from HTS data among non-inbred individuals only. The new revised version takes into account the possibility of individuals being inbred by estimating the 9 condensed Jacquard coefficients along with various other relatedness statistics. The program is threaded and scales linearly with the number of cores allocated to the process.

Conclusion
The program is available as an open source C/C++ program under the GPL license and hosted at https://github.com/ANGSD/ngsRelate. To facilitate easy analysis, the program is able to work directly on the most commonly used container formats for raw sequence (BAM/CRAM) and summary data (VCF/BCF).