bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tracking the timely dissemination of clinical studies. Characteristics and impact of 10 tracking variables
Authors: Strech Daniel , Sievers Sören , Märschenz Stefanie , Riedel Nico , Wieschowski Susanne , Meerpohl Jörg , Langhof Holger , Müller-Ohlraun Stephanie , Dirnagl Ulrich 
Published: November 2018

Background: Several meta-research studies and benchmarking activities have assessed how comprehensively and timely, academic institutions and private companies publish their clinical studies. These current “clinical trial tracking” activities differ substantially in how they sample relevant studies, and how they follow up on their publication. Methods: To allow informed policy and decision making on future publication assessment and benchmarking of institutions and companies, this paper outlines and discusses 10 variables that influence the tracking of timely publications. Tracking variables were initially selected by experts and by the authors through discussion. To validate the completeness of our set of variables, we conducted i) an explorative review of tracking studies and ii) an explorative tracking of registered clinical trials of three leading German university medical centres. Results: We identified the following 10 relevant variables impacting the tracking of clinical studies: 1) responsibility for clinical studies, 2) type and characteristics of clinical studies, 3) status of clinical studies, 4) source for sampling, 5) timing of registration, 6) determination of completion date, 7) timeliness of dissemination, 8) format of dissemination, 9) source for tracking, and 10) inter-rater reliability. Based on the description of these tracking variables and their influence, we discuss which variables could serve in what ways as a standard assessment of “timely publication”. Conclusions: To facilitate the tracking and consequent benchmarking of how often and how timely academic institutions and private companies publish clinical study results, we have two core recommendations. First, the improvement in the link between registration and publication, for example via institutional policies for academic institutions and private companies. Second, the comprehensive and transparent reporting of tracking studies according to the 10 variables presented in this paper.
A RESSIGNIFICAÇÃO DA DEMOCRACIA DIANTE DA(S) CRISE(S) DO ESTADO: UM NOVO CAMINHO FRENTE À RACIONALIDADE NEOLIBERAL
Authors: Brum Amanda Netto 
Published: November 2018

O presente estudo tem como tema central a ressignificação da democracia frente à(s) crise(s) do Estado no contexto da racionalidade neoliberal. Assim, por meio da técnica de pesquisa da documentação indireta da pesquisa bibliográfica, incialmente, apresenta-se o Estado diante das crises de seus fundamentos. Posteriormente, realiza-se uma reflexão acerca do processo e das consequências que a “fórmula da homogeneidade” proporciona aos sujeitos e ao próprio Estado. Finalmente, expõe-se a necessidade de (re)pensar a concepção da democracia atual frente à racionalidade neoliberal e, desse modo, propõe-se ressignificá-la por meio do aparato participativo da Fraser (2009), pois entende-se que tal construção teórica pode ser uma ferramenta potente – ao dar respostas aos novos questionamentos que se opõem no cenário atual – para reativar concepções emancipatórias e de empoderamento frente às novas subjetividades decorrentes da lógica neoliberal.
Ausencia de septum pellucidum en neonato expuesto a Zika durante gestación
Authors: Rodríguez Cindy V. , Calvete Yesid Blanco 
Published: November 2018

La epidemia del Zika y sus efectos a nivel neurológico, principalmente la microcefalia, han activado las alertas a nivel de Latinoamérica y Colombia debido al aumento de incidencia de estos casos; esto evidencia la necesidad de seguir los protocolos que permitan el adecuado diagnóstico materno y neonatal. A continuación, se presenta el caso de un neonato con sospecha de antecedente de exposición al virus Zika en su primer trimestre de gestación, sin anormalidades ecográficas pre natales ni déficit neurológico o microcefalia; en él, se evidenció mediante radiología la ausencia de septum pellucidum asociado a otras malformaciones a nivel cerebral mediante ecografía y TAC.
Dworkin’s Theory of Rights in the Age of Proportionality
Authors: Möller Kai 
Published: November 2018

Abstract
There is probably no conceptualization of rights more famous than Ronald Dworkin’s claim that they are “trumps.” This seems to stand in stark contrast to the dominant, proportionality-based strand of rights discourse, according to which rights, instead of trumping competing interests, ultimately have to be balanced against them. The goal of this article is to reconcile Dworkin’s work and proportionality and thereby make a contribution to our understanding of both. It offers a critical reconstruction of Dworkin’s theory of rights which does away with the misleading label of rights as “trumps” and shows that, far from being in conflict with proportionality, properly understood Dworkin’s work supports and supplements that doctrine and provides a much-needed account of its moral foundation as being about human dignity, freedom, and equality.
Proportionality & Comparative Constitutional Law versus Studies
Authors: Dixon Rosalind 
Published: November 2018

Abstract
The doctrine of proportionality has received sustained attention from comparative constitutional scholars. Yet it is an area where courts, and scholars, have made limited use of empirical or inter-disciplinary approaches to constitutional comparison. The article calls for a change in this practice as part of a broader call for greater dialogue between scholars and practitioners of conceptual and more empirical forms of constitutional comparison.
CD5 and CD43 expression are associate with poor prognosis in DLBCL patients
Authors: Huang Hui , Li Zhandong , Huang Chuansheng , Rao Jun , Xie Qin , Cui Wenhao , Tou Fangfang , Zheng Zhi 
Published: November 2018

Abstract

Objective
To investigate the expression and clinical significance of CD5 and CD43 in diffuse large B cell lymphoma (DLBCL) (unspecified).

Methods
Sixty - five patients with diagnosed DLBCL were enrolled. The expressions of CD5, CD43, CD10, Bcl-6 and Mun-1 were detected by immuno histochemistry. The relationship between CD5 and CD43 and clinicopathological features and prognosis of DLBCL was analyzed.

Results
In sixty - five adult DLBCL patients , 6 cases of DLBCL (9.2%) were CD5 positive, 24 cases of DLBCL (36.9%) were CD43 positive, 5 cases of DLBCL (7.7%) were both CD5 and CD43 positive. 40 cases of DLBCL (61.5%) were CD5 and CD43 negative. CD5 expression was not related to age, sex, clinical stage, type of immunophenotype (Hans typing), location, and whether infected with hepatitis B virus (HBV); CD43 expression was correlated with immunophenotyping and HBV i nfection, but was not correlated with the age, sex, clinical stage, and site. Median survival time was significantly lower in CD5- and CD43- positive DLBCL patients than CD5- and CD43-negative patien ts.

Conclusion
The prognosis of DLBCL patients may be worse with positive CD5 and CD43 expression.
Education, Human Rights, and Peace – Contributions to the Progress of Humanity
Authors: Lerman Zafra Margolin 
Published: November 2018

Abstract
I started my chemistry adventure while in high school, where I was the only female in a science and mathematics-oriented class. During our Junior year of high school, we were sent to the desert, close to the Red Sea in Israel to build roads. In the summers, we were in a Kibbutz on the border to help with the work needed. After work, we had time to discuss our future. Upon graduating from high school, I was drafted into the army, and in the evenings, started my college education and majored in chemistry. After finishing my term in the army, I continued my undergraduate studies in chemistry while raising my son. As I was conducting research on isotope effects, I realized that I wanted to make chemistry accessible to all. My tenet in life is that equal access to Science Education is a human right. I developed a method of teaching chemistry using art, music, dance, drama, and cultural backgrounds which attracted students at all educational levels to chemistry. I felt that as chemists, we have obligations to make the planet a better place for humankind. At this point, I became very active in working towards Scientific Freedom and Human Rights; helping chemists in the Soviet Union, China, Chile, Guatemala, and many other countries. The American Chemical Society established the Subcommittee on Scientific Freedom and Human Rights in 1986 and I chaired this committee for 26 years. At great risk to my personal safety, we succeeded in preventing executions, releasing prisoners of conscience from jail and bringing dissidents to freedom. This work led me to use chemistry as a bridge to peace in the Middle East by organizing Conferences which bring together chemists from 15 Middle East Countries with five Nobel Laureates. The Conferences allow the participants to collaborate on solutions to problems facing the Middle East and the World. The issues are; Air and Water Quality, Alternative Energy Sources, and Science Education at all Levels. Eight conferences were held and the ninth is scheduled for 2019. More than 600 Middle East scientists already participated in these conferences. Considering that most of the participants are professors or directors of science institutions who have access to thousands of students, the number of people in the network is in the thousands. Between the conferences, the cross-border collaborations are ongoing despite the grave situation in the Middle East. In these conferences, the participants succeed in overcoming the chasms of distrust and intolerance. They do not just form collaborations, but form friendships. Hopefully, we will manage to form a critical mass of scientists who will be able to start the chain reaction for peace in the Middle East. Commitment, perseverance, and many times, bravery, helped me to overcome the obstacles I encountered.
US Military Response to the Risk of Terrorist Attacks
Authors: Azam Jean-Paul , Thelen Véronique 
Published: November 2018

Abstract
This paper reports that the econometric findings of Azam & Thelen (2010) remain valid when the sample is extended by 10 years to cover 1990–2014 in Azam & Thelen (2018). They blame the presence of US troops in oil-exporting countries and their neighbors for increasing transnational terrorist attacks by nationals from these countries. They also confirm that foreign aid and educational capital are playing the opposite role by reducing the number of such attacks. The “Obama years” saw a lowered presence of US troops overseas and their smaller marginal impact on transnational terrorism.
Predicting Terrorism with Machine Learning: Lessons from “Predicting Terrorism: A Machine Learning Approach”
Authors: Basuchoudhary Atin , Bang James T. 
Published: November 2018

Abstract
This paper highlights how machine learning can help explain terrorism. We note that even though machine learning has a reputation for black box prediction, in fact, it can provide deeply nuanced explanations of terrorism. Moreover, machine learning is not sensitive to the sometimes heroic statistical assumptions necessary when parametric econometrics is applied to the study of terrorism. This increases the reliability of explanations while adding contextual nuance that captures the flavor of individualized case analysis. Nevertheless, this approach also gives us a sense of the replicability of results. We, therefore, suggest that it further expands the role of science in terrorism research.
Evaluierung der Sicherheit von Tiefbrunnen durch Ultraschallmessungen
Authors: Klieber Christoph , Brill Thilo M. 
Published: November 2018

Zusammenfassung
In der Öl- und Gasproduktion wird nach der Bohrung ein Stahlrohr, genannt Futterrohr, in das mehrere Kilometer tiefe Bohrloch eingeführt und der Ringraum zwischen Rohr und Gestein, genannt Annulus, mit Zement verfüllt. Die vollständige Füllung des Ringraums mit Zement bewirkt eine hydraulische Isolation der verschiedenen Produktionszonen: jegliche Flüssigkeits- oder Gasbewegung außerhalb des Futterrohres wird unterbunden, um mögliche Verschmutzung von Grundwasserschichten und Unfälle zu verhindern. Um die korrekte Füllung des Ringraums zu überprüfen, wird der Zement im Annulus nach Aushärtung in-situ durch akustische Messungen vermessen. Solche zerstörungsfreien Messungen müssen unter harschen Bedingungen (Sensortechnik und Elektronik arbeiten bei Drücken bis zu 2000 bar und Temperaturen bis zu 200°C) von der Innenseite des Futterrohres ausgeführt werden. Diese Messung soll mögliche Kanäle erkennen, die zu unerwünschten Flüssigkeits- oder Gasbewegungen außerhalb des Futterrohres führen können. Die genauesten Messungen basieren auf Ultraschalltechniken, die entweder den Abklang der natürlichen Resonanz des Futterrohres ausnutzen oder die Eigenschaften der niedrigsten symmetrischen und antisymmetrischen Schwingungsformen von Lambwellen im Futterrohr basieren. Das Gesamtvolumen aller Zementevaluierungsmessungen in der Öl- und Gasindustrie beläuft sich pro Jahr auf mehrere Milliarden Euro.
‘A Kind of Shadow’: Mirror Images and Alter Egos in Zadie Smith’s Swing Time
Authors: Quabeck Franziska 
Published: November 2018

Abstract
In Swing Time, her newest novel to date, Zadie Smith makes use of a first-person narrator for the first time in her career as a writer, and this change in narrative perspective is crucial to our understanding of the novel. Her narrator is slightly odd and we come to question the veracity of her account. Thus, she is ‘unreliable’ in traditional terms, but this article argues that we can equally call her inauthentic because she obviously represses feelings that are vital to the story. She does not fully expose herself, for she tries to hide the fact that she does not know who she is. Trapped between the intersectionality of race, class, and gender, oppressed by an overbearing mother and a racist society, the narrator has confined herself to an existence as a shadow. By way of Charles Taylor’s politics of recognition and Frantz Fanon’s image in the third person, this article tries to show that Swing Time’s narrator exists only as a shadow because she finds no external affirmation of herself as a black woman.
Factors Related to Healing Process of Sectio Caesarea Surgical Wound
Authors: Balla Juldin D. E. , Paun Rafael , Ludji Ina Debora Ratu 
Published: November 2018

ABSTRACT
Sectio caesarea surgical wound is a disorder in the incontinence of cells due to surgery performed to remove the fetus and placenta by opening the abdominal wall for certain indications. The aim of the study was to analyze and make a modeling of the relationship of factors in healing the sectio caesarea surgical wounds. This research is an analytic observational study with cross-sectional design. The sample in this study were 42 mothers with post sectio caesarea surgery at Prof. DR. W.Z. Johannes Kupang Public Hospital. Sampling was performed by simple random sampling. Data analysis was carried out in a bivariate and multivariate analysis. The results of the bivariate analysis found that the variables that give risk to wound healing were age (p = 0.041; RP = 3.4), discharge planning (p = 0.004; RP = 4.75), personal hygiene (p = 0.003; RP = 0.18), nutritional status (p = 0.013; RP = 0.15). Multivariate analysis found three variables that consistently provide risks to wound healing, namely discharge planning (p = -2.078; RP = 829 95% CI), personal hygiene (p = -1.852; RP = 1.039 95% CI), nutritional status (p = -2,374; RP = 1,023 95% CI). Probability model for healing the surgical wound at Prof. Dr. W.Z. Johannes, namely personal hygiene, nutritional status, discharge planning are factors related to wound healing.
Keywords : sectio caesarea, wound, discharge planning, personal hygiene

ABSTRAK
Luka operasi sectio caesarea adalah gangguan dalam inkontuinitas sel akibat dari pembedahan yang dilakukan untuk mengeluarkan janin dan placenta dengan membuka dinding perut atas indikasi tertentu. Tujuan penelitian untuk menganalisis dan membuat pemodelan hubungan faktor pada penyembuhan luka operasi sectio caesarea. Penelitian ini merupakan studi observasional analitik dengan desain cross sectional. Sampel pada penelitian ini sebanyak 42 ibu post operasi sectio caesarea di RSUD Prof. DR. W.Z. Johannes Kupang. Pengambilan sampel secara simple random sampling. Analisis data dilakukan secara bivariat dan multivariat. Hasil analisis bivariat menemukan variabel yang memberikan risiko terhadap penyembuhan luka adalah umur (p=0,041; RP=3,4), discharge planning (p=0,004; RP=4,75), personal hygiene (p=0,003; RP=0,18), status gizi (p=0,013; RP=0,15). Analisis multivariat menemukan tiga variabel yang konsisten memberikan risiko terhadap penyembuhan luka yaitu discharge planning (p= -2.078; RP=829 95% CI), personal hygiene (p= -1.852; RP= 1,039 95% CI), status gizi (p= -2.374; RP=1,023 95% CI). Model probabilitas penyembuhan luka operasi di RSUD Prof. Dr. W.Z. Johannes yaitu personal hygiene, status gizi, discharge planning merupakan faktor yang berhubungan dengan penyembuhan luka.
Kata kunci : sectio caesarea, luka, discharge planning, personal hygiene
Lacandonia granules are present in the cell nucleus of Welwitschia mirabilis
Authors: Agredano-Moreno Lourdes-Teresa , Segura-Valdez María de Lourdes , Jiménez-Ramírez Jaime , Jiménez-García Luis-Felipe 
Published: November 2018

Background: Lacandonia granules are extranucleolar ribonucleoprotein (RNPs) particles, 32 nanometers in diameter that were first described in the nucleus of Lacandonia schismatica . Cytochemical and immunocytochemical studies suggest that these particles are equivalent to perichromatin and Balbiani ring granules described in mammals and salivary glands cells of the insect Chironomus tentans, respectively. Lacandonia granules are also present in the related Triuris brevystilis , and they were later described in the gymnosperm Ginkgo biloba . These findings suggest that Lacandonia granules have a wider distribution in the plant kingdom. Species study: The plant Welwitschia mirabilis, a gymnosperm of the order Gnetales.Hyphotesis: Lacandonia granules are present in the cell nucleus of W. mirabilis . Methods: Plants were cultivated in a germination chamber and samples of leaves were processed for transmission electron microscopy. Thin sections were stained with the EDTA technique preferential for ribonucleoproteins and osmium amine specific for DNA and observed with a microscopy.Results: Light, electronic and atomic force microscopy revealed that cell nuclei of W. mirabilis display a reticulated arrangement of chromatin. Moreover, granules of 32.17 ± 1.7 nm in diameter were observed among strands of reticulated chromatin.Conclusions: Our results indicate that Lacandonia granules are present in the nuclei of the gnetal W. mirabilis.
Novel hybrid biofilm system using synthetically engineered curli fibres
Authors: Ramesh Harshini , Pasumarthi Keerthana , Hou Maggie , Lee Jennifer 
Published: November 2018

Hydraulic fracturing, a popular mining technique, generates heavy metal contamination in nearby freshwater aquifers. This poses a threat to both the surrounding ecosystems an human health if exposed. Existing methods of heavy metal removal can produce additional hazardous byproducts. This proposal presents the use of a hybrid biofilm filter containing graphene and curli fibres with metal binding sites. Curli fibres are amyloid fibrils found on the extracellular biofilm of Escherichia coli (E coli.). Through the use of plasmid vectors, E. coliwill be engineered to produce secreted curli fibres with metal-binding residues. The stability and cohesive properties of the curli fibres augments the adherence to the graphene scaffolding, thus allowing for generation of a hybrid biofilm. With the filtration design and various experimental controls proposed, this model is ready for empirical proof of concept and subsequent quantitative optimization.
Angry young man syndrome: anger based dominant hand injuries
Authors: Hongaiah Deepak , Sathanantham Dinesh Kumar , Sanganbhonia Spurthi 
Published: November 2018

Background: The incidence of self-inflicted anger related upper extremity injuries due to punching glass, involving dominant hand has increased in recent years even in our rural population of less than 1.5 million in District of Kolar, Karnataka, India. Although hospital stay is short, these patients require long term follow up, physiotherapy and occupational rehabilitation.Methods: This study is a case series involving a a retrospective analysis from June 1, 2015, to July 31, 2017. Our study involved only glass cut injury following an angry intention.Results: This study included 9 eligible patients who were all young male aged between 18 to 28 years (median age: 23.4 years) who had triggering factor before punching the glass pane. All patients had tendon injuries, flexors (n=4), extensor (n=3), both (n=2), muscle injuries (n=1), median nerve (n=2), radial artery (n=3). All injuries required operative intervention. Mean hospital stay was 5.2 days. Mean rehabilitation period was 5.2 months.Conclusions: These types of injuries can be prevented by regular counseling for stress/anger management as a part of rehabilitation to prevent further recurrences.
Efficacy of chemical sphincterotomy with 2% diltiazem cream vs. surgical sphincterotomy in the management of chronic fissure in ano: a clinical study
Authors: Kenche Jeevan , Reddy Chandrashekhar 
Published: November 2018

Background: Surgical intervention like lateral internal sphincterotomy is very effective and in a time of few weeks, healing can occur but there is danger of the anal incontinence. Hence alternative methods were sought like 2% diltiazem and other agents and they have been shown to lead to proper healing without anal incontinence. The objective was to study efficacy of chemical sphincterotomy with 2% diltiazem cream vs. surgical sphincterotomy in the management of chronic fissure in ano.Methods: A hospital based follow up study was carried out among 60 patients with chronic fissure in ano. They were randomly assigned in two groups. Group I consisted 30 patients who were treated with 2% diltiazem cream on outpatient basis. Group II patients i.e. 30 patients were operated for sphincterotomy. Both the group patients were followed for six weeks at two weeks interval. Outcome like complete healing, fecal incontinence, flatus incontinence was seen at follow up. Chi square test and t test were used to determine the significant difference between the groups.Results: Both the groups were comparable to each other in terms of age, sex, presenting symptoms, mean duration of symptoms and internal findings. Diltiazem group patients had significantly much better healing rate i.e. 96.7% compared to only 80% from patients with surgery group. Incidence of complications like fecal/flatus incontinence was zero in diltiazem group compared to 13.3%/20% in surgery group.Conclusions: Authors conclude that diltiazem 2% topical application is better than surgical sphincterotomy and should be used instead of surgery.