bluuebunny/crossref_metadata_2025_split huggingface dataset:
TUM‐Campus im Olympiapark München
Authors: Jamnitzky Jens , Deák Alexander 
Published: October 2019

AbstractBeim Projekt TUM‐Campus im Olympiapark wurde die gesamte Leistungsbreite des gegenwärtigen Ingenieurholzbaus abgerufen und umgesetzt. Neben der kompletten Dachkonstruktion sind die Sporthallen und die Institutsbereiche in Holzbauweise errichtet. Zum Einsatz kommen hierbei neben weitspannenden Brettschichtholzträgern auch Hybriddecken in Holz‐Beton‐Verbundbauweise mit einer Brettsperrholzbasis sowie vorgefertigte Holzrahmenwände und Deckenelemente, die z. T. auch verklebt wurden. Integrierte, deckengleiche Stahlunterzüge, die von BauBuche‐Dachträgern abgehängt werden, sind weitere Elemente des Holzbau‐Werkzeugkastens, die hier zum Einsatz kommen. Die Holzbauweise ermöglichte einen hohen Vorfertigungsgrad und dadurch kurze Montagezeiten. Mit einer entsprechenden Logistik für Planung, Fertigung, Anlieferung und Montage konnten die Hallencluster in jeweils nur zwei Monaten Bauzeit aufgerichtet werden.Prägend für die Bauaufgabe war die großzügige Überdachung im Bereich des Leichtathletikstadions: Die Laufbahnen sind auf einer Länge von ca. 150 m mit 40 Elementen großzügig überdacht. Die 28 m langen und 1,60 m hohen Dachelemente haben eine freie Auskragung von 18,3 m und schützen die 100‐m‐Laufbahn. Durch einen integrierten Querträger über der vorderen Stützenreihe gelingt die Punktlagerung der flächigen Vordachplatte. Die große Auskragung des Holzdachs wird durch verklebte Hohlkastenelemente möglich, die in ihren Dimensionen übliche Abmessungen überschreiten. Die Bauteile mit einer Breite von 3,75 m und der Gesamtlänge von 28 m wurden im Werk Ober‐Grafendorf bei St. Pölten in Niederösterreich im Rahmen einer Taktfertigung hergestellt und über Spezialtransporte und Autokräne an Ort und Stelle gebracht. Installationselemente wie Regenrohre und Elektroleitungen wurden bereits im Werk integriert und gewährleisteten so einen reibungslosen Montageablauf auf der Baustelle.Der Beitrag behandelt in Schlaglichtern die Anforderungen und Lösungen bei der Umsetzung dieser Bauaufgabe.
Palliative resection or radiation of primary tumor prolonged survival for metastatic esophageal cancer
Authors: Xu Jing , Lu Donghui , Zhang Li , Li Jian , Sun Guoping 
Published: October 2019

AbstractPurposeWe aimed to explore the value of palliative resection or radiation of primary tumor for metastatic esophageal cancer (EC) patients.MethodsSurveillance, Epidemiology, and End Results database was used for identifying metastatic EC patients. The patients were divided into resection and nonresection groups. And patients without resection were divided into radiation and nonradiation groups. Propensity score matching (PSM) analyses were adopted to reduce the baseline differences between the groups. Cancer specific survivals (CSSs) and overall survivals (OSs) were compared by Kaplan‐Meier (K‐M) curves. Multivariable analyses by COX proportion hazards model were performed to identify risk factors for CSS and OS. Predictive nomograms were conducted according to both postoperative factors and preoperative factors.ResultsA total of 7982 metastatic EC patients were selected for our analyses. After PSM, 978 patients were included in the survival analyses comparing palliative resection and nonresection. The CSS and OS for patients underwent palliative resection were significantly longer than those without resection (median CSS: 21 months vs 7 months, P < .001; median OS: 20 months vs 7 months, P < .001). In the overall population without resection, 654 patients were matched for radiation and nonradiation groups. And K‐M curves showed that patients with radiation had longer CSS and OS than those without radiation (median CSS: 11 months vs 6 months, P < .001; median OS: 10 months vs 6 months, P < .001). Nomograms were generated for prediction of 1‐, 2‐, and 3‐year CSS and OS. All C‐indexes implied moderate discrimination and accuracy. And all nomograms had good calibration.ConclusionPalliative resection or radiation of primary tumor could prolong CSS and OS of metastatic EC patients.
Solketal Formation in a Continuous Flow Process over Hierarchical Zeolites
Authors: Kowalska‐Kuś Jolanta , Held Agnieszka , Nowińska Krystyna 
Published: October 2019

AbstractGlycerol ketalization with acetone to solketal, an oxygenate fuel additive, was demonstrated over hierarchical zeolites of ZSM5, Beta and Mordenite structure in a continuous flow system. Micro‐mesoporous zeolites were prepared in two steps, by means of alkaline treatment with NaOH followed by the ionic exchange with NH4NO3 and a subsequent treatment with citric acid. The presence of mesopores in the applied catalysts was confirmed by N2 adsorption/desorption measurements and TEM microscopy. Hierarchical zeolites showed superior catalytic performance and lifetime over 24 hours under mild conditions (atmospheric pressure, acetone to glycerol molar ratio of 3 : 1, WHSV of 3–8 h−1, reaction temperature of 323 K). Glycerol conversion of about 90 % and selectivity to solketal up to 98 % have been obtained over micro‐mesoporous catalysts within 24 h without any drop of performance and the symptoms of clogging. Among all hierarchical catalysts tested in a flow reactor, the very high activity defined as solketal yield (88 %) showed ZSM5 and Beta zeolites.
Flexible NO2‐Functionalized N‐Heterocyclic Carbene Monolayers on Au(111) Surface
Authors: Dery Shahar , Kim Suhong , Tomaschun Gabriele , Haddad David , Cossaro Albano , Verdini Alberto , Floreano Luca , Klüner Thorsten , Toste F. Dean , Gross Elad 
Published: October 2019

AbstractInvited for the cover of this issue are Elad Gross, F. Dean Toste, and co‐workers at The Hebrew University and UC Berkeley. The image depicts the flexible anchoring geometry of addressable carbene molecules on Au surface, which upon exposure to reducing conditions changed their orientation from a standing into a flat‐lying position. Read the full text of the article at 10.1002/chem.201903434.
The influence of self‐criticism on depression symptoms among ambulatory patients with inflammatory bowel disease
Authors: Trindade Inês A. , Irons Chris , Ferreira Cláudia , Portela Francisco , Pinto‐Gouveia José 
Published: October 2019

AbstractConsidering that self‐criticism is an important process in the development and maintenance of depression, and taking into account the stigma associated with inflammatory bowel disease (IBD), the present study aimed to analyse whether self‐criticism exacerbates the relationships of depression symptoms with IBD symptomatology and chronic illness‐related shame.The sample included 53 ambulatory IBD patients (66% females) with ages from 18 to 65. Moderation analyses were conducted using structural equation modelling.Self‐criticism exacerbated the associations of depression with IBD symptoms (b = 0.01; standard error [SE] = 0.00;Z = 3.73;P < .001) and illness shame (b = 0.02;SE = 0.01;Z = 2.40;P = .016). For the same level of IBD symptomatology or chronic illness‐related shame, those individuals who present more feelings of inadequacy towards the self, experience more symptoms of depression. This exacerbation effect is stronger when IBD symptomatology and chronic illness‐related shame are more intense.A high self‐critical IBD patient may view the illness and/or symptomatology as a flaw or error that should be self‐corrected. Physicians and other health professionals should be attentive to these pathological mechanisms and should attempt to alleviate them. It may be beneficial to refer high self‐critical patients to psychological care.
Measuring therapeutic alliance in children with autism during cognitive behavior therapy
Authors: Burnham Riosa Priscilla , Khan Maria , Weiss Jonathan A. 
Published: October 2019

AbstractTherapeutic alliance (TA), or the collaborative relationship between a therapist and client, has been shown to be an important component of intervention success. The objective of this study was to examine the psychometric properties of the Therapy Process Observational Coding System–Alliance Scale (TPOCS‐A). The sample consisted of 20 children (19 males) ages 8 to 12 years with autism and their parents (15 mothers, 5 fathers), who completed a cognitive–behavioural intervention designed to improve children's emotion regulation skills. Two trained coders rated early, middle, and late parent and child alliance using the TPOCS‐A after watching video recorded therapy sessions. Therapist‐reported child involvement, alliance, and adherence were also assessed. Psychometric findings revealed that the TPOCS‐A is a reliable and valid measure of therapeutic alliance for children with autism. The implications of examining TA in empirically supported treatments for this population are discussed.
Rates of Ring Opening of Radical Cation Intermediates Govern Differences in Thermoluminescence between 1‐ and 2‐Naphthyl‐Substituted Methylenecyclopropanes
Authors: Matsui Yasunori , Shimono Kazuki , Takae Kosuke , Namai Hayato , Sera Toshiki , Ogaki Takuya , Ohta Eisuke , Mizuno Kazuhiko , Ikeda Hiroshi 
Published: October 2019

AbstractIn this study, we observed that methylenecyclopropane 1 c, possessing geminal phenyl and 1‐naphthyl groups at C‐2 of the three membered ring, emits green thermoluminescence (TL) in a low temperature matrix, associated with two sets of bands in the 480–600 and 600–700 nm regions. The bands are assigned to phosphorescence from 31 c* and triplet‐triplet (T−T) fluorescence (FL) from the corresponding trimethylenemethane biradical 32 c..*, respectively. In contrast, as previously reported, the analogous 2‐naphthyl derivative 1 b emits red TL associated with two bands in the 350–450 and 600–700 nm regions, which are assigned to FL from 11 b* and T−T FL from 32 b..*. The results of spectroscopic studies and density functional theory calculations show that the observed dissimilarity in the TL properties of 1 b and 1 c is a consequence of differences in the rate of methylenecyclopropane ring opening of 1 b.+ and 1 c.+ associated with stereoelectronic effects of the naphthyl groups.
Hydrogenation of Functionalized Nitroarenes Catalyzed by Single‐Phase Pyrite FeS2 Nanoparticles on N,S‐Codoped Porous Carbon
Authors: Duan Yanan , Dong Xiaosu , Song Tao , Wang Zhaozhan , Xiao Jianliang , Yuan Youzhu , Yang Yong 
Published: October 2019

AbstractInvited for this month′s cover is the group of Yong Yang at the Qingdao Institute of Bioenergy and Bioprocess Technology. The image shows single‐phase pyrite FeS2 nanoparticles with uniform size supported on N,S‐codoped porous carbon, which allows for highly active and chemoselective hydrogenation of functionalized nitroarenes bearing readily reducible groups to their corresponding anilines in water. The Full Paper itself is available at 10.1002/cssc.201901867.
Social instability in adolescence differentially alters dendritic morphology in the medial prefrontal cortex and its response to stress in adult male and female rats
Authors: Breach Michaela R. , Moench Kelly M. , Wellman Cara L. 
Published: October 2019

AbstractAdolescence is an important period for HPA axis development and synapse maturation and reorganization in the prefrontal cortex (PFC). Thus, stress during adolescence could alter stress‐sensitive brain regions such as the PFC and may alter the impact of future stressors on these brain regions. Given that women are more susceptible to many stress‐linked psychological disorders in which dysfunction of PFC is implicated, and that this increased vulnerability emerges in adolescence, stress during this time could have sex‐dependent effects. Therefore, we investigated the effects of adolescent social instability stress (SIS) on dendritic morphology of Golgi‐stained pyramidal cells in the medial PFC of adult male and female rats. We then examined dendritic reorganization following chronic restraint stress (CRS) with and without a rest period in adult rats that had been stressed in adolescence. Adolescent SIS conferred long‐term alterations in prelimbic of males and females, whereby females show reduced apical length and basilar thin spine density and males show reduced basilar length. CRS in adulthood failed to produce immediate dendritic remodeling in SIS rats. However, CRS followed by a rest period reduced apical dendritic length and increases mushroom spine density in adolescently stressed adult males. Conversely, CRS followed by rest produced apical outgrowth and decreased mushroom spine density in adolescently stressed adult females. These results suggest that stress during adolescence alters development of the PFC and modulates stress‐induced dendritic changes in adulthood.
Sediment and nutrient deposition in different riparian forests and floods of the Middle Paraná River
Authors: Marchetti Zuleica Yael , Massa Ernesto Segundo , Brumnich Federico 
Published: October 2019

AbstractSedimentation processes are important to the dynamics of lowland fluvial systems and depend on the characteristics of floods and of riparian ecosystems. The few known studies for the Paraná River system analysed only summer floods without considering the context in which the sedimentation occurred. This study focuses on sedimentation in three riparian forests during one summer and two winter floods of the Paraná River, quantifying the amount of deposited sediments, determining their texture, and measuring the associated quantities of Total Phosphorous (TP) and Total Nitrogen (TN). This study takes into account the elevations, floristic attributes, and geomorphologic context of the three forests, as well as water and sediment transport during floods. Differences in the floods' water discharge, wash load, and duration determined differences in the total amounts of drained water and mobilized sediments. The amount of sediments ranged from 0 to 510 kg m‐2 in the different floods and riparian forests studied. The texture was statistically different between the two winter floods, and between some riparian forests. The analysis of nutrients showed that 1 to 4919 kg ha‐1 of TP and 4.2 to 1152 kg ha‐1 of TN were deposited during the three floods in all forest types. Our results show that the amounts from winter floods can be as important as those from summer floods. These results provide insight not only into the importance of winter floods in the deposition processes, but also into the role of both types of floods as natural instruments of fertilization for floodplain–river ecosystems.
Diastereoselective Hydroxyethylation of β‐Hydroxyketones: A Reformatsky Cyclization‐Lactone Reduction Cascade Mediated by SmI2−H2O
Authors: Garduño‐Castro Monserrat H. , Procter David J. 
Published: October 2019

AbstractThe hydroxyethylation of β‐hydroxyketones allows diastereoselective access to important 1,3,5‐triols. The approach exploits a SmI2−H2O‐mediated Reformatsky cyclization‐lactone reduction cascade.
3D Bioconvective multiple slip flow of chemically reactive Casson nanofluid with gyrotactic micro‐organisms
Authors: Nayak M. K. , Prakash J. , Tripathi D. , Pandey V. S. , Shaw S. , Makinde O. D. 
Published: October 2019

AbstractIn the present study, we investigate the velocity, thermal, solutal, and motile micro‐organism (MM) slip effects on the flow of chemically reactive Casson nanofluid flowing over an exponentially stretched electromagnetic sheet in the presence of a chemical reaction. In addition, a mechanism of improving the motion of nanoparticles (Brownian motion and thermophoresis) is incorporated. The nondimensionalized ordinary differential equations are tackled by using symbolic computation software, MATLAB 2012b, with bvp4c function. Some significant and relevant characteristics of associated profiles are displayed graphically and discussed beautifully with the aid of tables through comprehensive numerical computations. The results of the study show that elevated Casson fluid parameter, gyrotactic micro‐organism, and electromagnetic strength belittle both axial as well as transverse velocities and the related momentum boundary layer thickness. Another important outcome is that low Prandtl fluids and enhancement in the strength of electromagnetic field fasten the diffusion of micro‐organisms, thereby augmenting the density of MM in the related boundary layer.
Contamination detection by optical measurements in a real‐life environment: A hospital case study
Authors: Inkinen Jenni , Ahonen Merja , Iakovleva Evgenia , Karppinen Pasi , Mielonen Eelis , Mäkinen Riika , Mannonen Katriina , Koivisto Juha 
Published: October 2019

AbstractOrganic dirt on touch surfaces can be biological contaminants (microbes) or nutrients for those but is often invisible by the human eye causing challenges for evaluating the need for cleaning. Using hyperspectral scanning algorithm, touch surface cleanliness monitoring by optical imaging was studied in a real‐life hospital environment. As the highlight, a human eye invisible stain from a dirty chair armrest was revealed manually with algorithms including threshold levels for intensity and clustering analysis with two excitation lights (green and red) and one bandpass filter (wavelength λ = 500 nm). The same result was confirmed by automatic k‐means clustering analysis from the entire dirty data of visible light (red, green and blue) and filters 420 to 720 nm with 20 nm increments. Overall, the collected touch surface samples (N = 156) indicated the need for cleaning in some locations by the high culturable bacteria and adenosine triphosphate counts despite the lack of visible dirt. Examples of such locations were toilet door lock knobs and busy registration desk armchairs. Thus, the studied optical imaging system utilizing the safe visible light area shows a promising method for touch surface cleanliness evaluation in real‐life environments.
Circulating MicroRNA-19b Identified From Osteoporotic Vertebral Compression Fracture Patients Increases Bone Formation
Authors: Sun Mengge , Hu Liqiu , Wang Shang , Huang Tongling , Zhang Minyi , Yang Meng , Zhen Wanxin , Yang Dazhi , Lu William , Guan Min , Peng Songlin 
Published: October 2019

ABSTRACT
Circulating microRNAs (miRNAs) play important roles in regulating gene expression and have been reported to be involved in various metabolic diseases, including osteoporosis. Although the transcriptional regulation of osteoblast differentiation has been well characterized, the role of circulating miRNAs in this process is poorly understood. Here we discovered that the level of circulating miR-19b was significantly lower in osteoporotic patients with vertebral compression fractures than that of healthy controls. The expression level of miR-19b was increased during osteoblastic differentiation of human mesenchymal stem cells (hMSCs) and MC3T3-E1 cells, and transfection with synthetic miR-19b could promote osteoblastic differentiation of hMSCs and MC3T3-E1 cells. PTEN (phosphatase and tensin homolog deleted from chromosome 10) was found to be directly repressed by miR-19b, with a concomitant increase in Runx2 expression and increased phosphorylation of AKT (protein kinase B, PKB). The expression level of circulating miR-19b in aged ovariectomized mice was significantly lower than in young mice. Moreover, the osteoporotic bone phenotype in aged ovariectomized mice was alleviated by the injection of chemically modified miR-19b (agomiR-19b). Taken together, our results show that circulating miR-19b plays an important role in enhancing osteoblastogenesis, possibly through regulation of the PTEN/pAKT/Runx2 pathway, and may be a useful therapeutic target in bone loss disorders, such as osteoporosis. © 2019 American Society for Bone and Mineral Research.
Influence of the history of abuse and suicidal attempts behavior among women victims of violence in Nicaragua
Authors: Rivas Esther , Bonilla Enrique , Vázquez José J. 
Published: October 2019

AbstractSuffering traumatic experiences linked to violence seems to be related to suicide attempts, especially, when the physical or sexual abuse has been experienced at an early age. This study examines the relationship between the history of abuse and suicide attempts among women victims of violence living in poverty in Nicaragua. This sample was subjected to a particularly serious range of stressful situations and experiences related to violence throughout their lives. The results show that women who experienced abuse during childhood were more likely to report a history of suicide attempts than women without a history of childhood abuse. Therefore, suicide attempts seem to be related more to those traumatic experiences during childhood than to violence suffered afterward. Identifying this type of abuse is particularly important because of its implications for the victims' health, as suicide attempts are maladaptive behaviors with which the women in the sample could have been addressing the trauma they experienced in their childhood. It is, therefore, necessary to highlight this problem in a developing country, which has been the focus of a limited number of studies, and where there are no support mechanisms for victims whose rights have been violated.
Identification of hub genes and construction of transcriptional regulatory network for the progression of colon adenocarcinoma hub genes and TF regulatory network of colon adenocarcinoma
Authors: Wei Shuxun , Chen Jinshui , Huang Yu , Sun Qiang , Wang Haolu , Liang Xiaowen , Hu Zhiqian , Li Xinxing 
Published: October 2019

AbstractThe aim of this study was to identify key genes related to the progression of colon adenocarcinoma (COAD), and to investigate the regulatory network of hub genes and transcription factors (TFs). Dataset GSE20916 including 44 normal colon, 55 adenoma, and 36 adenocarcinoma tissue samples was used to construct co‐expression networks via weighted gene co‐expression network. Gene Ontology annotation and the Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis for the objective module were performed using the online Database for Annotation, Visualization and Integrated Discovery. Hub genes were identified by taking the intersection of differentially expressed genes between dataset GSE20916 and GSE39582 and validated using The Cancer Genome Atlas (TCGA) database. The correlations between microRNA (miRNA) and hub genes were analyzed using the online website StarBase. Cytoscape was used to establish a regulatory network of TF‐miRNA‐target gene. We found that the orange module was a key module related to the tumor progression in COAD. In datasets GSE20916 and GSE39582, a total of eight genes (BGN, SULF1, COL1A1, FAP, THBS2, CTHRC1, COL5A2, and COL1A2) were selected, which were closely related with patients’ survivals in TCGA database and dataset GSE20916. COAD patients with higher expressions of each hub gene had a worse prognosis than those with lower expressions. A regulatory network of TF‐miRNA‐target gene with 144 TFs, 26 miRNAs, and 7 hub genes was established, including model KLF11‐miR149‐BGN, TCEAL6‐miR29B2‐COL1A1, and TCEAL6‐miR29B2‐COL1A2. In conclusion, during the progression of COAD, eight core genes (BGN, SULF1, COL1A1, FAP, THBS2, CTHRC1, COL5A2, and COL1A2) play vital roles. Regulatory networks of TF‐miRNA‐target gene can help to understand the disease progression and optimize treatment strategy.