bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medidas de protección respiratoria de tuberculosis en personal de salud: revisión integrativa
Authors: Muñoz Sánchez Alba Idaly , Antolinez Figueroa Carolina 
Published: October 2019

Introducción: los trabajadores de la salud (TS) son vulnerables a la infección por tuberculosis. Se suma el desconocimiento de los TS de las medidas de protección respiratoria que puede aumentar el riesgo individual de adquirir tuberculosis en instituciones de salud. Objetivo: describir la producción de literatura científica en las bases de datos científicas sobre las medidas de protección respiratoria de la infección tuberculosa durante el periodo 2012-2018. Síntesis de contenido: revisión integrativa a través de: formulación de la pregunta de investigación, recolección de datos, evaluación, análisis e interpretación de datos y presentación de los resultados. 45 artículos cumplieron con los criterios de inclusión. Las características predominantes de los estudios fueron: año 2017 con mayor número de publicaciones, en el continente de África, la metodología de estudio cuantitativo cuasiexperimental. En los estudios se identificaron las características del respirador N95 y la mascarilla quirúrgica, los conocimientos, actitudes y prácticas de las medidas de protección respiratoria y programas educativos. Conclusiones: se evidenció que el respirador N95 es la medida de protección individual más eficiente para el control de la infección tuberculosa en los TS. También se identificó la necesidad del diseño de programas educativos sobre las medidas de protección de la infección tuberculosa.
Avrupa Birliği Ülkelerinde Karbon Dioksit Emisyonu Politikaları Başarılı Olabilir mi? Kırılmalı Birim Kök Analizi
Authors: YILDIRIM Selim 
Published: October 2019

Avrupa Birliği çevre konusunda
duyarlı bir yaklaşıma sahiptir ve çevre koruma politikaları açısından önemli
adımlar atmaktadır. Avrupa Birliği sera gazı emisyonunu ilişkin olarak 1990
yılına kıyasla 2020’de %20 ve 2030’da
%40 düşüş hedeflemektedir. 2050 hedefi olarak ise Paris Anlaşmasına bağlı
kalarak küresel ısınmayı 2°C'nin altında, tercihen 1.5°C’de tutmak için gerekli
politikaları uygulamayı hedeflemektedir. Bu çalışma sera gazlar içinde CO2‘de
odaklanarak Avrupa Birliğinin sera gazı ile ilgili politikalarda başarılı olup
olamayacağını araştırmaktadır. Bu amaçla yirmi sekiz Avrupa ülkesine ait kişi
başı yıllık CO2 emisyonu serisi kırılmasız, bir kırılmalı ve iki
kırılmalı ADF birim kök testleri ile sınanmıştır. Kırılmalı birim kök testleri
birkaç durum dışında serilerin durağan olduğunu yani politikalar yapısal
değişiklik yaratırsa CO2
emisyonunu yeni trend etrafında hareket edeceğini; yani politikaların başarılı
olacağı yönünde bulgular ortaya koymuştur.
Is there a Role for Genetics in Cardiac Calcification?
Authors: Hellman Urban , Mörner Stellan , Henein Michael 
Published: October 2019

Calcific coronary artery disease (CCAD) may cause abnormal myocardial perfusion and hence generalized ischaemia, despite potential discrepancy in its expression pattern compared to the well-known atherosclerotic disease which raises questions about the exact pathophysiology of coronary calcification and whether there is a genetic aetiology for it. In a pilot study we studied three candidate genes, ENPP1, ABCC6 and NTE5 which may predispose to coronary arterial or valvular calcification. We studied 65 patients with CCAD and 5 patients with calcific aortic valve disease (CAVD). Five DNA variants potentially affecting protein function were found in six patients. Our findings support genetic variants might influence the development of CCAD and CAVD, however, segregation in the families must first be performed to ascertain any damaging effect of these variants. The search for direct causative genetic variants in coronary artery and aortic valve calcification must be broadened with other genes.
RESVERATROL IN KUBAN WINES
Authors: L. P. Troshin , A. V. Milovanov , Guguchkina  , A. V. Prakh , Е. А. Beliakova 
Published: October 2019

Purpose: The main purpose of viticulture is to improve the quality of the grapes, both to a greater extent for ampelotherapy and winemaking, and, to a lesser extent, to onotherapy.
Methodology: The article highlights the results of perennial (from 2014) studies of 18 promising technical grape varieties from different zones of the Krasnodar Territory: Anapo-Taman, Central, as well as Amur from the Black Sea zone of the Krasnodar Territory and two control Western European world-famous and most common varieties Merlot and Cabernet-Sauvignon in the same zones.
Result: The average values of resveratrol were found in wine materials from the varieties Vladimir and Dmitry (4.7 mg / dm3), Podlesny (3.9 mg / dm3), Saperavi Severny (3.5 mg / dm3), 40 let Octiabria (3.3 mg / dm3), Kurchansky and 40 let Pobedy (3.0 and 2.9 mg / dm3, respectively). On the other hand, as shown by the analysis of wine materials, the Antaris, Varyushkin, Mitsar and Plechistik varieties synthesize a lower content of resveratrol (1.0 and 0.9 mg / dm3, respectively).
Applications: This research can be used for the universities, teachers and education students.
Novelty/Originality: In this research, the model of resveratrol in Kuban wines is presented in a comprehensive and complete manner.
COMPENSATION, ORGANIZATIONAL COMMUNICATION, AND CAREER PATH AS DETERMINANTS OF EMPLOYEE PERFORMANCE IMPROVEMENT
Authors: Indrasari Meithiana , Syamsudin Nur , Bambang Purnomo Raditya , Yunus Eddy 
Published: October 2019

Purpose: The present study investigated the effects of compensation, organizational communication, and career path to employee performance of a transformer distributor company (PT Bambang Djaya) in Surabaya Indonesia because the above three variables were important aspects of improving the employee performance.
Methodology: The data was collected by a Likert Scale questionnaire and analyzed using the multiple linear regression. The participants were 117 employees and selected using a purposive sampling technique.
Result: The results showed that the compensation, organizational communication, and career paths had significant effects simultaneously on employee performance; and the career path was the strongest determinant of employee performance.
Applications: This research can be used for universities, teachers, and students.
Novelty/Originality: In this research, the model of the compensation, organizational communication, and career path as determinants of employee performance improvement is presented in a comprehensive and complete manner.
INSTITUTIONAL MECHANISMS OF UNIVERSITY TEACHER PROFESSIONAL DEVELOPMENT
Authors: A. Shibankova Lyutsia , V. Ignatieva Alla , A. Belokon Igor , M. Kargapoltsev Sergey , A. Ganaeva Elena , A. Beroeva Elena , N. Trubenkova Svetlana , B. Kozlova Elena 
Published: October 2019

Purpose of the study: Conditions of qualifications’ dynamic development, rapid obsolescence of existing competencies actualize the need to create a system of continuous professional growth of teachers on staff training. The purpose of the article is to develop organizational mechanisms that contribute to the professional growth of the teacher inflexible response conditions of education to socio-economic changes.
Methodology: The research methodology relies on the lifelong education concept, defining the design principles of a teacher professional growth system: consistency, continuity, self-development, participative nature, pedagogical reflexing
Results: The system of the teacher’s professional growth in the educational institution possessing properties of hierarchy, flexibility, and dynamism is developed. The principles and organizational mechanisms for this system’s implementation are revealed: corporatism as a way to create targeted educational platform based on digital technology; tutoring as the insurance of the teacher’s and the educational organization’s interests through the accompany of career advancement; branding as a result of the teacher’s and the educational organization’s competitiveness in the market of educational services; road maps for planning, monitoring and support of the teacher’s career development.
Applications of this study: The article is intended for teachers, managers, employees of personnel services of educational organizations.
Novelty/Originality of this study: For the first time the self - learning system of the teacher professional growth is offered which is capable to exist and productively function in modern dynamic conditions at the expense of adaptive organizational mechanisms of reaction to social and economic changes.
The Effect of Variety and Harvesting Time of Sorghum Planted in Stylosanthes Pasture on Growth, Production and Prussic Acid Content
Authors: Dewi Meita Puspa , Umami Nafiatul , Suhartanto Bambang 
Published: October 2019

This research was aimed to determine the growth, production and prussic acid content of sorghum variety that planted on stylosanthes pasture with different harvesting time. This research was done using split-plot design with three replications which sorghum variety (brown midrib resistance (BMR) and Super-2) as the main plot and harvesting time (6, 8 and 10 weeks) as the sub plot. The sorghum seeds were germinated for 12 days before planted on the 30 days stylosanthes pasture which was planted with planting space 25 x 25 cm. Sorghum was planted with planting space 75 x 25 cm. The variables observed were plants height, dry and organic matter production and prussic acid. Data obtained were analyzed statistically using analysis of variance and significantly different between means were tested with Duncan's New Multiple Range Test (DMRT). Sorghum BMR had plant height, dry and organic matter production higher (P<0.05) than Super-2. Prussic acid content of BMR was lower (P<0.05) than Super-2. The older harvesting time increase (P<0.05) plant height, dry matter and organic production, but reduced (P<0.05) prussic acid content from 727.34 mg/kg to 241.71 mg/kg. Based on the results it can be concluded that the oldest harvesting time (10 weeks) produced the highest dry and organic matter, and reduce prussic acid content. Sorghum BMR is more productive and grew faster than Super-2. Sorghum BMR that harvested in 10-week shows the best in growth and productivity also had lower prussic acid content.
Quantitative Analysis of Integrity Failures in Subsea Oil Wells Using a Markovian Model
Authors: Colombo Danilo , de Abreu Danilo Taverna Martins Pereira , Martins Marcelo Ramos , Lima Gilson Brito Alves , Neves Maurício Moraes , Garcia Pauli Adriano de Almada , Frutuoso e Melo Paulo Fernando Ferreira 
Published: October 2019

Summary
Well-integrity management is a key activity to prevent hydrocarbon leakages during the oilwell life cycle. Accordingly, qualitative techniques associated with the monitoring, testing, and checking of well integrity are widespread in the industry. However, there is still space to advance in terms of quantitative approaches that support the decision making regarding what action to perform when a failure occurs and, additionally, the resource planning without overlooking the risks. In line with this, we propose a Markovian model that allows computing the probability of uncontrolled hydrocarbon releases into the environment. This paper includes a case study demonstrating the model application and the impact of considering successful component tests and evidence of failures.
Lessons learned from engaging communities for Ebola vaccine trials in Sierra Leone: Reciprocity, reliability, relationships and respect (The Four R’s)
Authors: Dada Sara , McKay Gillian , Mateus Ana L. , Lees Shelley 
Published: October 2019

Abstract
Background

Building trust and engaging the community are important for biomedical trials. This was core to the set up and delivery of the EBOVAC-Salone and PREVAC Ebola vaccine trials in Sierra Leone during and following the 2014-2016 West African Ebola epidemic. Local community liaison teams (CLT) engaged with the community through public meetings, radio chat shows, and other activities, while a social science team (SST) assessed community members’ and participants’ perceptions and regularly updated the clinical team to adapt procedures to improve the acceptability and compliance of the trial. The objective of this study was to examine the community engagement (CE) program in these trials and to identify potential barriers and facilitators.Methods

Fifteen CLT and SST members participated in in-depth interviews and 23 community members attended three focus groups to discuss the Ebola vaccine trials and their experiences and perspectives of the CE activities.Results

A key aim of the CE program was to build trust between the community and the trial. Four main principles (the “four R’s”) evolved from the discussions with team members and the community that influenced this trust: reciprocity, relatability, relationships and respect. The CLT and SST ensured reciprocal communication between the trial and the community. The CLT delivered key messages from the trial, whilst the SST completed ethnographic research in the field to uncover rumors and perceptions of the trial in the community. These ethnographic findings were shared with the CLT and addressed in targeted messaging to the community. Both the CLT and SST approached the communities in an egalitarian manner, by dressing modestly, speaking local dialects, and using relatable examples. Appreciation and understanding of the importance of interpersonal relationships and respect for the people, their customs, and traditions also played a large role in the CE program.Conclusion

These findings provide an in-depth understanding of how interdisciplinary community liaison and social science teams can work with a clinical team to strengthen trust. The four R’s suggest the ways in which trust relations are central to CE and confidence in vaccine trials, and could offer an approach to CE in vaccine trials.
Identification of two novel COL10A1 heterozygous mutations in two Chinese pedigrees with Schmid-type metaphyseal chondrodysplasia
Authors: Kong Lingchi , Shi Li , Wang Wenbo , Zuo Rongtai , Wang Mengwei , Kang Qinglin 
Published: October 2019

Abstract
Background: Schmid-type metaphyseal chondrodysplasia (MCDS) is an autosomal dominant disorder caused by COL10A1 mutations, which is characterized by short stature, waddling gait, coxa vara and bowing of the long bones. However, descriptions of the expressivity of MCDS are rare.
Methods: Two probands and available family members affected with MCDS were subjected to clinical and radiological examination. Genomic DNA of all affected individuals was subjected to whole-exome sequencing, and candidate mutations were verified by Sanger sequencing in all available family members and in 250 normal control donors. A spatial model of the type X collagen (α1) C-terminal noncollagenous (NC1) domain was further constructed.
Results: We found that the phenotype of affected family members exhibited irregular dominance. Mutation analysis indicated that there were two novel heterozygous missense mutations, [c.1765T>A (p.Phe589Ile)] and [c.1846A>G (p.Lys616Glu)] in the COL10A1 gene in family 1 and 2, respectively. The two novel substitution sites were highly conserved and the mutations were predicted to be deleterious by in silico analysis. Furthermore, protein modeling revealed that the two substitutions were located in the NC1 domain of collagen X (α1), which potentially impacted the trimerization of collagen X (α1) and combination with molecules in the pericellular matrix.
Conclusion: Two novel mutations were identified in the present study, which will facilitate diagnosis of MCDS and further expand the spectrum of the COL10A1 mutations associated with MCDS patients. In addition, our research revealed the phenomenon of irregular dominance in MCDS.
Enhancement of Aeribacillus pallidus lipase production through optimization of medium composition using Box behnken design and its application in detergents formulations
Authors: KTATA Ameni , aida karray , Mnif Ines , BEZZINE Sofiane 
Published: October 2019

Abstract
Background : Alkaline, thermostable bacterial lipases are very interested at detergent applications, seen that they replace the use of synthetic detergents which cause substantial environmental problems. These enzymes based detergent are eco friendly and produce a waste water with low level of COD (Chemical Oxygen Demand). The present study, investigates a newly isolated Aeribacillus pallidus strain produces, without induction, a novel halophilous, thermo-alkaline and detergent- tolerant lipase.
Results: Considerable interest has been given to this lipase by the improvement of its production by the optimization of the pH, the (C/N) ratio and the inoculums size, using the response surface methodology based on the Box-Behnken Design of experiments. A total of 16 experiments were conducted, and the optimized pH, (C/N) ratio and inoculums size were 10, 1 and 0.3 respectively. The results of the analysis of variance (ANOVA) test indicated that the established model was significant (p value < 0.05).
Conclusions: A 6.68-fold of increase in enzyme activity was revealed under the optimized conditions with the maximum activity of 68 U/mL. Additionally, lipase of Aeribacillus pallidus is considered as a potential candidate for applications in detergent formulations since it displayed a good stability towards detergents and wash performance.
The performance of anthropometric measures to predict diabetes mellitus and hypertension among adults in Jordan
Authors: Khader Yousef , Batieha Anwar , Jaddou Hashem , El-Khateeb Mohammad , Ajlouni Kamel 
Published: October 2019

Abstract
Objectives: This study aimed to evaluate and compare the abilities of waist circumference (WC), body mass index (BMI), hip circumference (HC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) to predict recently and previously diagnosed diabetes and hypertension and assess their appropriate cut-off values among Jordanian adults.
Methods: Data from the 2017 cardiovascular risk factors survey were analyzed to achieve the study objective. The survey collected extensive data from a national population-based sample of Jordanian residents. A structured questionnaire was used to collect sociodemographic variables and clinical data. Blood samples were taken for biochemical measurements. Anthropometric characteristics were measured by the same team of trained field researchers.
Results: This study included a total of 1193 men and 2863 women. Their age ranged from 18 to 90 year with a mean (SD) of 43.8 (14.2) year. WHtR performed better than other anthropometric measures and had a good ability (AUC>0.80) among women and fair ability among men to predict newly diagnosed diabetes and previously diagnosed diabetes and hypertension. The appropriate cut-off points for anthropometric measures among women were 92 cm form WC, 104 cm for HC, 30 Kg/m2 for BMI, 0.85 for WHR, and 0.60 for WHtR. For men, the appropriate cut-off points were 100 cm for WC, 104 cm for HC, 27 Kg/m2 for BMI, 0.93 for WHR, and 0.57 for WHtR.
Conclusion: WHtR performed better than other anthropometric measures in predicting diabetes and hypertension among adult population in Jordan. We recommend WHtR as a measure of choice with a cut-off value of 0.6 for women and 0.57 for men to predict diabetes and hypertension among Jordanians.
The Dental complications of canine tooth bud removal in 2-12 years old children in North West Ethiopia
Authors: Teshome Amare , Assefa Berihun 
Published: October 2019

Abstract
Abstract
Objective: Canine tooth bud removal is a process of gouging out an infant’s canine tooth buds, using unsterile tools such as Sharpe blade, garlic, or knitting needle, without anesthesia. The aim of the study was to reveal dental complications of canine tooth bud removal among children visited the dental clinic of the University of Gondar hospital. This study was an institution-based cross-sectional conducted from January 2015-September 2016 at university of Gondar hospital on 2-12 years children. The tooth was assessed for whether it had previously oral mutilated or not. In addition to this, the oral cavity was evaluated for the presence of missed, malformed or normal canine
Results : A group of 355 children aged 2-12 years was examined clinically. The mean age of the children was 7.32±3.12 (SD). The prevalence of canine tooth bud removal was 86.8% which was high in 6-9 years old (54.87%) and first position children (40.26%). The most common dental complications were; malformed enamel (hypoplastic) canine (48.5%) and missed/Unerupted canine (38.6%).
LncRNA regulates tomato fruit cracking by coordinating gene expression via a hormone-redox-cell wall network
Authors: Xue Lingzi , Sun Mintao , Wu Zhen , Yu Lu , Yu Qinghui , Tang Yaping , Jiang Fangling 
Published: October 2019

Abstract
Background
Fruit cracking occurs easily under unsuitable environmental conditions and is one of the main types of damage that occurs in fruit production. It is widely accepted that plants have developed defence mechanisms and regulatory networks that respond to abiotic stress, which involves perceiving, integrating and responding to stress signals by modulating the expression of related genes. Fruit cracking is also a physiological disease caused by abiotic stress. It has been reported that a single or several genes may regulate fruit cracking. However, almost none of these reports have involved cracking regulatory networks.
Results
Here, 0, 8 and 30 h irrigation treatments resulted in the differential expression of 1028 mRNAs and 87 lncRNAs in ‘LA1698’ (cracking resistant, CR) at 8 h_vs_0 h, 468 mRNAs and 15 lncRNAs in CR_30 h_vs_CR_0 h, 321 mRNAs and 19 lncRNAs in CR_30 h_vs_CR_8 h; 531 mRNAs and 75 lncRNAs in ‘LA2683’ (cracking susceptible, CS) at 8 h_vs_0 h, 420 mRNAs and 24 lncRNAs in CS_30 h_vs_CS_0 h, 270 mRNAs and 20 lncRNAs in CS_30 h_vs_CS_8 h; and 339 mRNAs and 64 lncRNAs in the two contrasting tomato genotypes at 0 h, 338 mRNAs and 94 lncRNAs at 8 h, and 369 mRNAs and 77 lncRNAs at 30 h. The GO pathways of the differentially expressed mRNAs were mainly enriched in the ‘hormone metabolic process’, ‘cell wall organization’, ‘oxidoreductase activity’ and ‘catalytic activity’ categories. In addition, the lncRNAs regulated the expression of their neighbouring genes, and genes related to tomato cracking were selected to construct a lncRNA-mRNA network influencing tomato cracking.
Conclusions
This study provides insight into the responsive network for water-induced cracking in tomato fruit. Specifically, lncRNAs regulate the hormone-redox-cell wall network, including plant hormone (auxin, ethylene) and ROS (H 2 O 2 ) signal transduction and many cell wall-related mRNAs ( EXP, PG, XTH ), as well as some lncRNAs (XLOC_010878 and XLOC_016662, etc.).