bluuebunny/crossref_metadata_2025_split huggingface dataset:
КАЗУС МАРИИ ВСЕВОЛОЖЕЙ: ВЕРСИЯ ОСЕТИНСКОГО ПРОИСХОЖДЕНИЯРУССКОЙ КНЯГИНИ
Authors: С.М. ПЕРЕВАЛОВ 
Published: November 2024

В статье рассматриваются версии происхождения Марии Шварновны († 1206), первой жены великого князя Владимирского Всеволода Большое Гнездо. На XVIII Всемирном русском соборе 2014 г. по инициативе североосетинской делегации ее провозгласили осетинкой (аланкой, яской) с прозвищем Мария Ясыня. Некоторые историки считают Марию чехиней (или моравой). Автор принимает версию, согласно которой вероятным отцом Марии был киевский боярин Шварн (Жирославич?), неоднократно упоминаемый в русских летописях. Осетинское происхождение великой княгини по источникам не прослеживается. Прозвище ясыня прилагалось только к младшей сестре Марии, жене Мстислава Святославича, о которой известно, что до замужества она проживала во Владимире-на-Клязьме под покровительством Всеволода. Cестры принадлежали к высшему русскому обществу и не имели контактов с Кавказской Аланией.
The article deals with the origins of Maria Shvarnovna († 1206), the first wife of Vsevolod III «Big Nest». Her origins are disputed. On the XVIII World Russian People's Council she has been identified as Ossetian (Alan), Maria Jassynja. Some scholars say she was Czech or Moravian. In the author’s opinion, Maria’s father was Kievan boyar Shvarn, who was not Ossetin (Alan, Jas). Nickname jassynja was applied only to the younger Maria’s sister, the wife of Mstislav Svjatoslavich, her place of residence was Vladimir-on-Klyazma. The sisters are belonged to the Russian princes’ circle and had no contact with Caucasian Alania.
Inteligência artificial e rizomas da ação comunicativa na ágora digital
Authors: Brennand Edna Gusmão de Góes , Dutra Delamar José Volpato 
Published: November 2024

O texto busca discutir paradoxos do debate público na era da Inteligência Artificial. Parte da concepção de esfera pública de Habermas e sua aplicabilidade no seio das reflexões atuais sobre o debate público e suas novas modalidades potencializadas pelas tecnologias digitais. Pretende trazer ao escrutínio das reflexões as formas de como jovens adultos de diferentes países garantem sua participação na esfera pública digital através do exercício da cidadania, da consolidação de uma sociedade bem-informada e coautora de seus sistemas político e jurídico. Na configuração da ágora digital, o uso da inteligência artificial em diferentes enquadramentos sociais e políticos originam diferentes níveis de participação, uma vez que estamos situados em três domínios de fronteiras difusas: Mundo analógico (cidadãos desconectados) Mundo digital (cidadãos conectados) e Mundo híbrido (cidadãos e máquinas conectados). Se, conforme argumenta Habermas, a vida em sociedade não é possível sem a comunicação e a relação com o outro, como garantir diálogo e consenso no mundo híbrido? Como pensar a democracia no cyberespaço e em uma esfera pública, que agregue vontades, argumentos, posições, defesas e consensos?
Criptoanálise
Authors: Preger Guilherme de Figueiredo 
Published: November 2024

Este artigo apresenta uma revisão do conceito de Inteligência Artificial pela ótica da transformação digital, que é, alegadamente, uma transformação dos meios de produção. Esta transformação acaba por confundir o terreno da produção, local histórico da análise marxista, com o da reprodução social, levando a uma expansão do campo de análise social para além das fronteiras econômicas tradicionais. É observado que a plataformização é a arquitetura hegemônica que acomoda a transformação digital. Ela amplia o cercamento dos bens comuns próprio ao sistema capitalista acrescentando uma mercadoria fictícia, a informação, às demais já presentes (terra, trabalho, dinheiro). Cria-se mais uma camada de regime de acumulação, que denomino de “espetacularização”. Como modelo para esta abordagem, é sugerido o método estratégico da criptoanálise que se estabelece pelo tratamento da distinção transparência/opacidade, proposta pelo sociólogo Niklas Luhmann. Observa-se que esta é a distinção que rege o princípio da complexidade. Com isso, é possível rastrear os danos gerados pelos usos indiscriminados da Inteligência Artificial generativa, que estão latentes (ocultos) na adoção da tecnologia. O artigo finaliza com uma reflexão sobre o alcance do arcabouço legal e regulatório que está sendo pensado no Brasil para esta nova tecnologia.
Lidocaine Induces Neurotoxicity by Activating the CaMKII and p38
MAPK Signaling Pathways through an Increase in Intracellular Calcium
Ions
Authors: Ma Qian , Wang Meng , Zhang Bin , Jia Danting , Chen Xuexin 
Published: November 2024

Background:
Lidocaine is extensively utilized as an anesthetic in clinical settings; however,
it has demonstrated significant neurotoxicity when administered for spinal anesthesia. The specific
mechanisms underlying lidocaine-induced neurotoxicity are poorly understood.

Objective:
This study aimed to investigate the mechanisms through which lidocaine induces neurotoxicity,
focusing on its effects on intracellular calcium release and the activation of CaMKⅡ and
MAPKs pathways, as well as to evaluate the potential protective effects of cilnidipine.

Methods:
The investigation has employed both in vitro cell models and in vivo mouse models to
conduct the experiments. Neuronal cell viability has been assessed following lidocaine treatment,
and neurological function has been evaluated in mice after intrathecal injection of lidocaine. Intracellular
calcium levels, CaMKⅡ activation, and the phosphorylation of p38 and p65 have been measured
in cultured hippocampal neuronal cells and mouse brain tissues. The effects of the calcium
channel blocker cilnidipine on these parameters have also been examined.

Results:
Lidocaine treatment led to a reduction in cell viability in cultured neuronal cells and induced
neurological dysfunction in mice. It increased intracellular Ca2+ levels and activated CaMKⅡ
in both cultured neuronal cells and mouse brain tissues. Lidocaine also elevated the phosphorylation
levels of p38 and p65 in neuronal cells. These effects have been suppressed by cilnidipine, indicating
a calcium-dependent mechanism.

Conclusion:
This study suggests that lidocaine induces neurotoxicity through a calcium-dependent
activation of CaMKⅡ and MAPK pathways, leading to neuronal apoptosis and dysfunction.
Cilnidipine has been found to exhibit promise as a protective agent against lidocaine-induced neurotoxicity.
The Role of Peer Relationships in Problematic Internet Use among Adolescents: A Scoping Review and Meta-analysis
Authors: Andrianie Prilya Shanty , Japar Muhammad , Pratisti Wiwien Dinar , Kasturi Taufik , Purwandari Eny 
Published: November 2024

Background
The swift advancement of technology, particularly the internet, has significantly influenced various aspects of human life, resulting in both positive and negative consequences. In Indonesia, adolescents represent the largest group of internet users, with usage durations exceeding four hours per day, making them vulnerable to issues such as Problematic Internet Use (PIU). During adolescence, peer relationships play a crucial role in social development.

Objective
This study aims to explore how peer relations can influence problematic internet use among adolescents and identify strategic factors that contribute to reducing PIU based on systematic review findings. Additionally, the research seeks to quantify the relationship between peer relations and problematic internet use among adolescents through meta-analysis. The hypothesis posits a correlation between peer relations and problematic internet use among adolescents.

Methods
The research employs scoping review and meta-analysis techniques.

Results
Scoping review results indicate that, overall, peer relationships can have both positive and negative impacts on PIU. A more positive relationship between adolescents and their peers tends to correlate with lower levels of PIU. Conversely, adolescents with problematic peer relationships are more likely to develop PIU behaviours. Meta-analysis results further strengthen these findings, demonstrating a significant correlation between peer relationships and problematic internet use among adolescents (r = 0.191; p = 0.020; 95% CI).

Conclusion
Despite the significant correlation, the influence of peer relationships on problematic internet use appears to be relatively low. This suggests the existence of other factors that contribute to PIU behaviours beyond peer relationships.
Challenges Faced by Newly Appointed Teachers at Autism- specific School: A Thematic Analysis Study
Authors: Mpangane Elmon , Maepa Mokoena Patronella , Muhadisa Tshimangadzo 
Published: November 2024

Introduction
Learners with Autism Spectrum Disorder (ASD) present with challenges in their social communication, social interactions, and repetitive patterns of behavior. These challenges significantly impact the provision of education by newly appointed teachers with limited experience in teaching learners with ASD.

Aim and Objective(s)
The purpose of this study was to explore the challenges faced by teachers working in autism-specific schools. The study sought to achieve this aim by understanding the experiences of teachers who are newly appointed at autism special schools.

Methodology
A qualitative research design was used, with two focus group discussions conducted with a total of 16 participants (9 participants in group 1 and 7 participants in group 2) working in autism-specific schools. The main research question included the following: What are the challenges encountered by new teachers in autism special schools? A Thematic Content Analysis was used to analyze the data collected from these discussions.

Result(s)
The study identified several challenges faced by teachers working in autism-specific schools. The challenges included managing challenging behaviors such as temper tantrums, meltdowns, communication difficulties, and disciplining learners.

Conclusion
Other problems encountered by teachers included limited resources, lack of support, and lack of training and professional development opportunities.
Investigating the Effectiveness of the Health-promoting Lifestyle Educational Program on Suicidal Thoughts in Healthcare Workers
Authors: Abiri Elaheh , Raesi Rasoul , Kashani Maryam Haji Ghasem 
Published: November 2024

Background
Suicide is a crisis, and its occurrence in healthcare workers (HCWs) is a special challenge that requires urgent interventions.

Aim
This study was conducted to determine the effectiveness of the health promotion lifestyle training program on suicidal thoughts in HCWs.

Methods
This one-sample longitudinal study was conducted using a multi-stage sampling method on 248 healthcare providers in 2023. In the first stage, the Beck scale was used to measure suicidal thoughts, and the DASS-21 was used to measure depression, anxiety, and stress. In the second stage, individuals with suicidal thoughts were placed in a separate group, and educational intervention continued for them. The health promotion lifestyle training protocol was provided to this group as a training program, and researchers followed up on its implementation for 95 days. In the third stage, after the completion of the educational intervention, the Beck scale and DASS-21 were once again provided to the target group. Data were analyzed in SPSS-25 statistical software.

Results
27.8% of participants had suicidal thoughts, 7.66% represented high-risk suicidal ideation, and 20.1% had low-risk suicidal ideation. 69 HCWs who had suicidal thoughts used the Health-Promoting Lifestyle Education Program for 95 days. The percentage of suicidal thoughts in people with high suicidal risk ideation decreased from 7.66% to 4.03% (p<0.05), and in people with low-risk suicidal ideation decreased from 20.1% to 13.30% (p<0.05).

Conclusion
Health promotion educational programs can be used as an effective intervention in improving mental health indicators and reducing suicidal thoughts in HCWs.
Analysis of Influencing Factor for Rear-end Crash on Toll Road: An Examination Using Self-reported Questionnaires
Authors: Didin Fatin Saffanah , Widyanti Ari , Puspasari Maya Arlini , Zuraida Rida , Triyanti Vivi , Hanowski Richard Joseph , Iridiastadi Hardianto 
Published: November 2024

Background
Rear-end crashes on toll roads have been a significant issue in Indonesia. This type of crash exists and needs a mitigation strategy. However, limited research exists examining the mechanism and contributing factors of these crashes in Indonesia. This research aimed to describe how rear-end crashes have occurred on toll roads in Indonesia, describe associated risk factors, develop a model for assessing the risk of rear-end crashes on Indonesian toll roads and identify potential mitigation strategies.

Materials and Methods
A questionnaire was developed and assessed for validity and reliability. It was distributed (online) to 220 drivers who had experienced a rear-end crash or near-crash in the past year.

Results
The findings from this study showed that contributing factors are driver (55%), environment (33%), and vehicle (12%). Subject vehicles usually consisted of private vehicles, while the lead (struck) vehicles included private vehicles (91.8%), trucks (7.27%), and buses (0.93%).

Discussion
This study also found two phenomena of local unique behavior in Indonesian toll roads that lead to rear-end crashes, such as “Lane Hogger” and driving under the speed limit (trucks) that lead other vehicles to rear-end crashes.

Conclusion
Factors contributing to rear-crash risk on Indonesian toll roads were driving experience (ownership driving license 15-20 years), breaking driving rules, driving in the right lane, and using an MPV. The findings from this study can improve potential mitigation strategies, including developing focused driving rules, traffic signs on toll roads, and crash avoidance technology.
Digital health literacy in Norwegian patients with hip and knee arthroplasty: normative data from a cross-sectional study
Authors: Rognsvåg Turid , Nordmo Ingrid K , Bergvad Ingvild B , Fenstad Anne M , Furnes Ove , Lerdal Anners , Lindberg Maren F , Skou Søren T , Badawy Mona 
Published: November 2024

Background and purpose: As digital health services become increasingly important in osteoarthritis treatment, understanding patients’ digital health literacy (eHL) is crucial, including those undergoing total hip and knee arthroplasty (THA/TKA). We primarily aimed to provide eHL norms in a representative group of Norwegian patients, and secondarily to examine the relationships between eHL and health-related quality of life (QoL).Methods: We invited 800 randomly selected THA/TKA patients from the Norwegian Arthroplasty Register to complete a paper-based questionnaire, which included sociodemographic variables. eHL was measured using the eHealth Literacy Questionnaire (eHLQ) with 7 domains: Using technology, Understand, Engage, Control, Motivation, Access, and Needs, scored from 1 (strongly disagree) to 4 (strongly agree). The EuroQol EQ-5D-5L measured health-related QoL. We used multivariable regression to examine relationships between eHL domains and health-related QoL controlling for sociodemographic variables.Results: Respondents’ (N = 383, 48%) mean age was 70 years (SD 9.0) and 246 (64%) were female. Mean eHLQ and the proportion of patients with low eHL (≤ 2.5) were Technology 2.7 (34%), Understanding 3.0 (14%), Engage 2.7 (28%), Control 3.2 (7.7%), Motivation 2.8 (35%), Access 2.8 (33%), and Needs 2.6 (46%). Low eHL correlated with older age and low education, but not with sex or type of surgery. Regression analyses showed that lower scores on the domains Technology, Engage, Control, Access, and Needs were associated with poorer QoL after adjusting for sociodemographic factors.Conclusion: About one-third of THA/TKA patients have low eHL, and low eHL was associated with poor QoL.
Clinical prediction models for patients undergoing total hip arthroplasty: an external validation based on a systematic review and the Dutch Arthroplasty Register
Authors: Belt Maartje , Smulders Katrijn , Schreurs B Willem , Hannink Gerjon 
Published: November 2024

Background and purpose: External validation is a crucial step after prediction model development. Despite increasing interest in prediction models, external validation is frequently overlooked. We aimed to evaluate whether joint registries can be utilized for external validation of prediction models, and whether published prediction models are valid for the Dutch population with a total hip arthroplasty.Methods: We identified prediction models developed in patients undergoing arthroplasty through a systematic literature search. Model variables were evaluated for availability in the Dutch Arthroplasty Registry (LROI). We assessed the model performance in terms of calibration and discrimination (area under the curve [AUC]). Furthermore, the models were updated and evaluated through intercept recalibration and logistic recalibration.Results: After assessing 54 papers, 19 were excluded for not describing a prediction model (n = 16) or focusing on non-TJA populations (n = 3), leaving 35 papers describing 44 prediction models. 90% (40/44) of the prediction models used outcomes or predictors missing in the LROI, such as diabetes, opioid use, and depression. 4 models could be externally validated on LROI data. The models’ discrimination ranged between poor and acceptable and was similar to that in the development cohort. The calibration of the models was insufficient. The model performance improved slightly after updating.Conclusion: External validation of the 4 models resulted in suboptimal predictive performance in the Dutch population, highlighting the importance of external validation studies.
IDENTIFIKASI SIFAT – SIFAT KUANTITATIF BIBIT DOMBA GARUT BETINA DI UPTD – BPPTDK MARGAWATI
Authors: Nawawi Ikhsan , Rohayati Tati , Herawati Ervi 
Published: November 2024

Sifat kuantitatif domba Garut merupakan sifat-sifat yang dapat diukur serta dijadikan pedoman dalam pemilihan bibit calon induk dan pejantan. Penelitian bertujuan untuk mengetahui bibit domba Garut betina di UPTD-BPPTDK Margawati yang telah memenuhi Standar Nasional Indonesia. Penelitian dilaksanakan di UPTD-BPPTDK Margawati Garut Sukanegla, Kecamatan Garut Kota, Kabupaten Garut pada bulan Juli 2022. Metode penelitian menggunakan metode survei terhadap domba garut betina calon induk. Sampel penelitian ditentukan secara purposive, yaitu calon induk yang berumur 8 – 12 bulan. Parameter yang diamati meliputi berat badan, panjang badan, tinggi pundak dan lingkar dada. Hasil penelitian menunjukkan dari 39 ekor domba betina calon indukan yang berumur 8 - 12 bulan diperoleh sebanyak 27 ekor (69,23%) domba telah sesuai dengan Standar Nasional Indonesia (SNI 7532.1:2015), sisanya 30,77% belum sesuai SNI.
Programación Maestra de la Producción de una Planta de Alimentos para Mascotas mediante una Metodología de Optimización basada en Horizonte Rodante
Authors: Cusimano Joan , Rios Romina , Herrero Fernando , Faba Emilce , Marchetti Pablo 
Published: November 2024

Este trabajo aborda la Programación Maestra de la Producción (PMP) de una planta de elaboración de alimentos para mascotas. El proceso de fabricación consiste en varias etapas, comenzando con la dosificación de las materias primas y nalizando con el envasado y almacenamiento del producto final. La planta cuenta con un número fijo de líneas de producción, siendo el equipamiento crítico las extrusoras y envasadoras disponibles. Dado un horizonte de mediano plazo (3 a 5 meses) desagregado en semanas, para cada línea se desea denir los volúmenes de producción por producto, los cuales se encuentran asociados a diferentes familias. Se desarrolló un modelo matemático mixto-entero lineal (MILP), considerando las principales restricciones del problema, combinado con un algoritmo de Horizonte Rodante para la resolución del horizonte completo. La metodología propuesta fue aplicada al problema de PMP de una instalación industrial de gran escala, que elabora cientos de productos y familias. En base a las dimensiones del problema, se realizó un análisis de parámetros del algoritmo para encontrar el mejor balance entre tiempo y calidad de la solución. Como resultado, al aplicar la metodología propuesta se obtuvieron mejoras considerables en cuanto a indicadores clave como lote mínimo por familia, cumplimiento de la política de stock y tiempos de resolución en comparación con el método vigente.
Evaluación de Desempeño de Servidores Supervisores MQTT Instalados en la Nube
Authors: Pazos Fernando 
Published: November 2024

La comunicación entre dispositivos en una red exige el uso de protocolos. En internet hay protocolos muy conocidos que pueden ser usados tanto en la arquitectura de un servidos con múltiples clientes como en una comunicación máquina a máquina (M2M). En aplicaciones de Internet de las Cosas (IoT), la comunicación en una red puede ser administrada por un servidor denominado supervisor, y el protocolo más ampliamente usado en la camada de aplicación con este propósito es MQTT (Message-Queuing Telemetry Transport). Este artículo compara el desempeño de ocho servidores supervisores instalados en la nube disponibles publicamente en tres experimentos bajo diferentes condiciones de exigencia. El objetivo es elegir el supervisor más adecuado para ser usado en la comunicación entre un nanosatélite del tipo Cubesat y el terminal de Tierra.
Concepciones de docentes de cursos introductorios de programación en relación con las competencias enunciadas en estándares
Authors: Piccin Ana , Hadad Graciela , Cicinelli Diana 
Published: November 2024

Mediante un estudio realizado sobre concepciones didácticas de los docentes de cursos introductorios de programación se han obtenido resultados con respecto a las competencias que dichos profesores consideran necesarias alcanzar en estos cursos. Dichas concepciones fueron categorizadas en competencias y posteriormente analizadas respecto a las competencias genéricas y específicas incluidas en la propuesta de CONFEDI y a los contenidos curriculares básicos establecidos por CONEAU. Este análisis ha permitido observar que los docentes no valorarían de manera uniforme las competencias que se proponen desarrollar en sus cursos y que esto estaría relacionado con el enfoque que cada uno hace de la enseñanza. La teoría postula que la relación entre concepciones didácticas de los docentes y el enfoque que dan a la enseñanza se corresponderían biunívocamente, existiendo estudios experimentales que verifican esta relación. Por ello se clasificaron las competencias concebidas fundamentales entre los docentes de los cursos introductorios según sus enfoques de enseñanza. Los resultados obtenidos permitirían esbozar lineamientos para la gestión de competencias según su impacto en el currículo de la carrera, así como planes de capacitación docente.