bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASPECTOS ÉTICOS DA ESTABILIZAÇÃO PROTETORA EM ODONTOPEDIATRIA
Authors: Martins Amanda Correia , Dias Francilena Maria Campos Santos , Silva Karime Tavares Lima da 
Published: November 2024

A odontopediatria desempenha um papel crucial na promoção da saúde bucal infantil, e a estabilização protetora é uma prática essencial para garantir o tratamento adequado das crianças. Este trabalho tem como objetivo analisar os aspectos éticos envolvidos na estabilização protetora, enfatizando a importância do consentimento informado, da comunicação efetiva e do respeito à dignidade do paciente. A metodologia adotada inclui uma revisão bibliográfica de artigos relevantes e diretrizes éticas na odontologia, bem como entrevistas com profissionais da área para compreender suas percepções sobre a prática ética. Os resultados evidenciam que a maioria dos odontopediatras reconhece a necessidade de uma abordagem ética que considere o bem-estar da criança e a construção de um ambiente seguro e acolhedor. Além disso, foram identificadas lacunas na formação acadêmica em relação à ética, sugerindo a necessidade de maior ênfase nos currículos. A pesquisa aponta que o consentimento informado, a empatia e a comunicação são pilares fundamentais para a prática ética na estabilização protetora. A maioria dos profissionais entrevistados concorda que a ética deve ser um componente central na relação com as crianças e suas famílias, assegurando que todas as intervenções sejam compreendidas e aceitas. Assim, este estudo contribui para a reflexão sobre as práticas odontológicas, destacando a relevância de uma formação ética sólida para os profissionais, além de sugerir melhorias na comunicação e no envolvimento dos responsáveis nos cuidados de saúde bucal infantil.
OS IMPACTOS DAS LICENÇAS ESTENDIDAS NAS LICENÇAS-MATERNIDADE DAS TRABALHADORAS CELETISTAS
Authors: Aires Luana Sávia A , Falcão Maurin Almeida 
Published: November 2024

TEMA: Busca o presente trabalho apresentar um estudo sobre os efeitos na dilatação dos prazos das licenças do Programa Empresa Cidadã na licença-maternidade constitucional das trabalhadoras celetistas no Setor Privado. OBJETIVOS: analisar os impactos positivos e negativos para as mulheres da extensão dos prazos das licenças por nascimento de filho, estabelecidas na Lei nº11.770/2008. METODOLOGIA: a pesquisa é qualitativa de natureza exploratória e o método de abordagem do problema descritivo dos modos de concessão e custeio das licenças estendidas do Programa Empresa Cidadã, baseados nos relatórios da ANDI Comunicação e Direito (2021) e Family Talks and 4Daddy (2022), levantamento histórico e revisão bibliográfica do instituto nos últimos cinco anos. RESULTADOS: os achados indicam que a extensão de sessenta dias para a mãe é benéfica ao aleitamento materno até os 6(seis) meses da criança, porém a amamentação não é exclusiva, os quinze dias concedidos ao pai, embora acarretem melhor adaptação à nova rotina doméstica, ainda é inóspita à carga de responsabilidade materna. Quanto à natureza contributiva, é baixa a adesão das empresas aptas à inscrição, além de o acesso ser impactado não só pela desigualdade de tratamento das empresas e dos gêneros, como também por classe social e raça. CONCLUSÃO: As licenças estendidas são um plus à formação de vínculo entre pais e filhos, contudo, os termos para os cuidados nos primeiros meses da criança não se limitam apenas aos prazos das licenças, assim como não garantem às trabalhadoras, ao término das garantias, a permanência no trabalho.
Reconceptualizing Teachers as First Responders
Authors: Sam Cecile , Gupton Jarrett 
Published: November 2024

This conceptual paper builds upon prior ideas of teacher work in the United States to include the role of “first responder” and highlights how this idea can change the current approach to understanding their work experience. We answer the following questions: 1. Why should we include first-responders as part of our conceptualization of teachers and the work that they do? 2. How would this reconceptualization change how we currently understand the nature of the teacher work experience? This paper expands upon existing literature of teachers, especially those who work with vulnerable populations.
STRUCTURAL CAPITAL EFFICIENCY AND FINANCIAL PERFORMANCE
Authors: AKINBODE, FEYISAYO AANUOLUWAPO  , OKEWALE, JOEL ADENIYI  , ADEDEJI, SAMUEL BABATUNJI  
Published: November 2024

The study examined how structural capital efficiency affected Nigerian publicly traded companies' financial results. It used a sample of Nigerian companies to examine the relationship between structural capital efficiency and important financial indicators, such as ROA and ROE. A descriptive study design was employed, utilizing an ex-post facto methodology. Twenty-two companies were purposefully chosen from a total of 151 publicly listed firms in Nigeria for this analysis, focusing on their financial statements. The sample included 11 manufacturing firms, 5 ICT companies, 3 health services providers, and 3 oil and gas enterprises, spanning a period from 2013 to 2022. The analysis made use of panel data techniques and a number of post-estimation tests, such as random effects models, fixed effects, and Ordinary Least Squares (OLS). In order to maintain accuracy and handle endogeneity concerns, the SGMM was also utilized. The results of the study indicated that while SCE had a positive, non-significant influence on ROE (p-value = 0.3886, β = 0.168, t-value = 0.8638), it had a significant positive effect on ROA (p-value = 0.0029, β = 0.0206, t-value = 3.0141). These results showed that while structural capital efficiency had a favorable but statistically insignificant effect on ROE, it greatly increased ROA. The study's conclusions suggest that management should give structural capital development top priority in order to enhance financial results since it has a positive effect on the financial performance of Nigerian businesses.
TRADE LIBERALIZATION AND ECONOMIC GROWTH IN SELECTED WEST AFRICAN COUNTRIES
Authors: OSUNAIYE DAVID SOLOMON  , MARCELLINA ODUH  , ILEMONA ADOFU  , OBADIAH JONATHAN GIMBA  
Published: November 2024

This research examines the relationship between trade liberalization and economic growth in selected West African countries (Cote d‟Ivoire, Ghana and Nigeria) the choice of these countries is as a result of steady GDP growth over the years, using secondary data in a multivariate panel framework for the period 1976 - 2023. The main objective was to establish the effects of trade liberalization on economic growth in these countries. The Autoregressive Distributed Lag (ARDL) bound tests and other diagnostic tests were employed for data estimation. The results indicated long run relationship between trade liberalization and economic growth in Cote d‟Ivoire, Ghana and Nigeria. The relationship is positive and significant for the three countries. In the long run, the combination of other macroeconomic variables like investment, human capital, net inflow of FDI and the exchange rate complement the contribution of trade to economic growth. Therefore, these countries should promote appropriate trade policies devoted to foster increased local production of manufactured and agricultural goods to reduce importation and stimulate exports, as a strategy to boost economic growth
Pengaruh Enabling Factors terhadap Perilaku Pencegahan Hipertensi pada Pra Lanjut Usia Berisiko di Puskesmas Tamalate Kota Makassar
Authors: Hijrah Hijrah , Asrina Andi 
Published: November 2024

WHO berkomitmen untuk menurunkan tingkat hipertensi pada lansia dengan fokus pada pendidikan kesehatan yang kuat, promosi gaya hidup sehat, dan pemberian akses yang lebih baik terhadap layanan kesehatan. Meningkatkatnya kesadaran akan risiko hipertensi, masyarakat akan lebih cenderung mengadopsi gaya hidup sehat, termasuk diet yang seimbang dan olahraga teratur, serta akan lebih aktif dalam melakukan pemeriksaan tekanan darah rutin. Masyarakat yang telah berusia lansia, menjadi rentan mengalami penyakit hipertensi, akibat dari pembuluh arteri yang kurang fleksibel lagi Dalam tiga tahun terakhir, Puskesmas Tamalate memiliki jumlah pasien dengan hipertensi tertinggi. Tahun 2021, ada 11.963 kasus hipertensi; tahun 2022, ada 12.874 kasus; dan tahun 2023, dari Januari hingga September, ada 10.158 kasus hipertensi. Penelitian ini merupakan jenis penelitian kuantitatif yang dirancang sebagai studi cross-sectional. Teknik Pengumpulan sampel dilakukan menggunakan Teknik Sampling purposive terdiri dari 172 individu orang pra lanjut usia (45-59 tahun) yang berisiko mengalami hipertensi. Hasil Penelitian didapatkan tidak ada pengaruh faktor pemungkin/ enabling factors ketersediaan dan akses pelayanan kesehatan (Nd); Ada pengaruh sarana dan prasarana (0,026) terhadap perilaku pencegahan hipertensi pada pra lanjut usia berisiko. Perlu adanya kontribusi kepala dan seluruh jajaran staf Puskesmas Tamalate Kota Makassar agar sedapat mungkin menyediakan akses pelayanan kesehatan juga sarana prasarana yang menunjang kebutuhan dalam upaya pencegahan pra lansia terhadap risiko kejadian hipertensi.
Peran Coder Terkait Keakuratan Pengkodean ICD-10 Pada Pelaksanaan Sistem INA-CBG’s Rumah Sakit TK. II 14.05.01 Pelamonia Makassar
Authors: Ekawati Dian , Nuryadin Adriyana Adevia , Windarti Sriyani , Zulfikar Andi 
Published: November 2024

Dalam pelaksanaan JKN, kegiatan coder klaim BPJS Kesehatan dimulai dengan menerima dokumen rekam medis pasien BPJS dari unit assembling. Kemudian, jika ada kesalahan, dokumen tersebut dipisahkan dan dikirim ke bagian yang terkait untuk diperbaiki terlebih dahulu. Selanjutnya adalah menentukan kode penyakit dan prosedur medis. Tujuan penelitian, untuk mengetahui peran coder terkait keakuratan pengkodean ICD-10 pada pelaksanaan sistem INA-CBG’s di Rumah Sakit TK.II 14.01.05 Pelamonia Makassar. Metode ini menggunakan penelitian kualitatif. Pengumpulan data melakukan dengan wawancara kepada Kepala Casemix, Kepala Rekam Medis, Petugas Coder dan Petugas Rekam Medis. Hasil dan Kesimpulan menunjukkan bahwa petugas rekam medis dan petugas coder rata-rata memiliki pengalaman yang mencukupi untuk menjalankan proses pengkodean klaim BPJS, walaupun masih terdapat beberapa permasalahan yang biasa dialami petugas. Petugas coder sudah mendapatkan pendidikan yang sesuai tentang pengkodean dan beberapa petugas pernah mengikuti seminar INA-CBG’s sehingga mengetahui apa itu INA-CBG’s dan juga fungsinya. Namun, masalah yang paling umum yang dihadapi petugas coder termasuk penulisan diagnosis penyakit yang sering disingkat, perbedaan antara tindakan yang ditulis dan dilaporkan DPJP.
Population size and structure of Grant’s gazelle and lesser kudu in Geralle National Park, Southeastern Ethiopia
Authors: Aychew Melkamu , Girma Zerihun , Yilma Zenebe Ageru 
Published: November 2024

Background
Grant’s gazelle and lesser kudu remain widespread within and outside protected areas. Current pressures on their populations, human encroachment and disturbance associated habitat modifications, and excessive grazing pose further threats to the species. The estimation of density and abundance of species has significant value for sustainable wildlife management in Geralle National Park (GNP) and also contributes towards a more accurate global population estimate.

Result
Using distance sampling methods, the lowest Akaike Information Criterion (AIC) (close to zero) and Chi-square tests (P value > 0.05) showed that the hazard rate key function with an un-equal interval group model was selected for estimation of density and abundance. The density of species was 1.7 ± 0.5, 2.07 ± 0.7, gazelle/km2 and 1.39 ± 0.3, 1.92 ± 0.42, lesser kudu/km2 during the dry and wet seasons, respectively. Population density, abundance, and structure showed habitat and seasonal differences in observation. More individuals of both species were recorded during the wet season as compared to the dry season. Grassland was favored by Grant’s gazelle, while lesser kudu preferred woodlands. Both species exhibited a female-biased sex ratio, indicating potential for future population growth prospects.

Conclusion
It can be concluded that GNP is home to viable populations of Grant’s gazelle and lesser kudu, and season has influenced population abundance and distribution due to resource availability variations among seasons. The female-biased sex ratio indicates the future population growth prospects for the two species.
Developing a Bright NIR‐II Fluorophore with Fast Renal Excretion and Its Application in Molecular Imaging of Immune Checkpoint PD‐L1
Authors: Wan Hao , Ma Huilong , Zhu Shoujun , Wang FeiFei , Tian Ye , Ma Rui , Yang Qinglai , Hu Zhubin , Zhu Tong , Wang Weizhi , Ma Zhuoran , Zhang Mingxi , Zhong Yeteng , Sun Haitao , Liang Yongye , Dai Hongjie 
Published: October 2018

AbstractFluorescence imaging in the second near‐infrared (NIR‐II) window holds impressive advantages of enhanced penetration depth and improved signal‐to‐noise ratio. Bright NIR‐II fluorophores with renal excretion ability and low tissue accumulation are favorable for in vivo molecular imaging applications as they can render the target‐mediated molecular imaging process easily distinguishable. Here, a probe (anti‐PD‐L1‐BGP6) comprising a fluorophore (IR‐BGP6) covalently bonded to the programmed cell death ligand‐1 monoclonal antibody (PD‐L1 mAb) for molecular imaging of immune checkpoint PD‐L1 (a targeting site upregulated in various tumors for cancer imaging) in the NIR‐II window is reported. Through molecular optimization, the bright NIR‐II fluorophore IR‐BGP6 with fast renal excretion (≈91% excretion in general through urine within the first 10 h postinjection) is developed. The conjugate anti‐PD‐L1‐BGP6 succeeds in profiling PD‐L1 expression and realizes efficient noninvasive molecular imaging in vivo, achieving a tumor to normal tissue (T/NT) signal ratio as high as ≈9.5. Compared with the NIR‐II fluorophore with high nonspecific tissue accumulation, IR‐BGP6 derived PD‐L1 imaging significantly enhances the molecular imaging performance, serving as a strong tool for potentially studying underlying mechanism of immunotherapy. The work provides rationales to design renal‐excreted NIR‐II fluorophores and illustrate their advantages for in vivo molecular imaging.
Nonlinear Supramolecular Polymers for Therapeutic Applications
Authors: Chen Wenzhuo , Kretzschmann Annika , Tian Wei , Wu Si 
Published: October 2018

AbstractAn elegant combination of supramolecular polymers exhibiting nonlinear topological structures results in a series of brand new, nonlinear supramolecular polymers. Recently, these polymers have attracted increased attention in various fields due to their diverse and advantageous properties. Especially in therapeutic applications, one can take advantage of their unique chemical, physical, and biological properties such as degradability and stimuli‐responsiveness. Due to the large number of possible module modifications, such polymers have great potential as platforms in disease treatments. In this review, the structures, properties, and functions of different nonlinear supramolecular polymers are summarized. Current therapeutic applications are presented and the prospective design trends are discussed for promoting the development of nonlinear supramolecular polymers.
Multiscale Modeling and Simulation of Nano‐Carriers Delivery through Biological Barriers—A Review
Authors: Shi Xinghua , Tian Falin 
Published: October 2018

AbstractThe past several decades have witnessed the explosion of nanomedicine for cancer therapy, where notable research efforts have been made in synthesizing and delivering nano‐carriers (NCs) to specific tumor sites. The effective treatment of cancer with nanomedicine poses the requirements of high solubility, prolonged circulation, low toxicity, strong targeting ability, specific distribution, and high tissue penetration capability of NCs, involving interdisciplinary research and posing challenges to the community. Along with experimental contributions for the development and application of NCs to treat cancer, multiscale modeling and simulation have also made considerable contributions to the understanding of the synthesis, translocation, and delivery of NCs and their payloads. Here, recent advances of modeling and simulation work are selected to elucidate some key concepts, methods, and applications of NCs during synthesis and drug delivery, such as assembly, translocation, targeting, cellular uptake, and penetration in tissue. The advantages and limitations of each method are highlighted, and the future perspectives in this field are also discussed.
Production and Emulsifying Effect of Esters on The Basis of Polyglycerol and Еpoxidized Derivatives of Sunflower and Soybean Oil
Authors: Shikhaliev Khidmet S. , Stolpovskaya Nadezhda V. , Krysin Mikhail Y. , Zorina Anna V. , Lyapun Denis V. , Zubkov Fedor I. 
Published: October 2018

AbstractOligo and polyesters of polyglycerol and polyricinoleic acid are widely used as emulsifiers in various industries. New promising emulsifiers for oil–water systems were obtained based on the condensation of glycerol and its oligomers with epoxidized derivatives of vegetable oils. The type of the resulting emulsion was studied. The influence of the composition of the emulsion and the hydrophilic–lipophilic balance (HLB) of the emulsifier on the type of the resulting emulsions was investigated. It was shown that the synthesized emulsifiers significantly increase the viscosity of the emulsion. Complex structural and functional spectral analysis of synthesized substances showed that the main reactions leading to the formation of the desired products were the opening of epoxide cycles, the transesterification of esters, and the condensation of fatty‐acid derivatives. This new combination of renewable raw materials is of undoubted interest for deeper chemical processing of vegetable oils.
Improving Oxidative Stability of Skin‐Care Emulsions with Antioxidant Extracts from Brown Alga Fucus vesiculosus
Authors: Hermund Ditte B. , Heung Shuk Yee , Thomsen Birgitte Raagaard , Akoh Casimir C. , Jacobsen Charlotte 
Published: October 2018

AbstractSkin‐care products are known delivery systems of functional lipids that can enhance the natural defense of skin. Unsaturated lipids, e.g., linoleic acids, are more susceptible to lipid oxidation than saturated lipids. Therefore, lipid oxidation must be prevented to preserve the functionality of the unsaturated lipids in skin‐care products. The antioxidant properties of two Fucus vesiculosus extracts (water extract [WE] and 80% [v/v] ethanol extract [EE]) were evaluated. Both extracts had high in vitro antioxidant properties and a high phenolic content. The antioxidant efficacy of the extracts was evaluated by addition of 0.05% and 0.1% (w/w) freeze‐dried extracts to facial cream formulations. The cream was stored up to 42 days (dark, 20 °C) and the oxidative stability was determined by following tocopherol consumption and development in peroxides and secondary oxidation products. The results showed that EE was able to reduce the peroxide oxidation rate from 84.8% (control without extract) to 41.3%. Furthermore, a higher efficacy was observed for EE over WE. This was most likely related to higher phenolic content, high radical‐scavenging activity, and moderate metal‐chelating ability. However, WE indicated regeneration of tocopherols by amphiphilic polyphenolic phlorotannins, with interfacial properties. The results show that F. vesiculosus extracts rich in antioxidative phlorotannins can play an important role in reducing lipid oxidation and maintaining the quality of cream.
Experimental measurements and modelling of CO2 solubility in aqueous mixtures of benzylamine and N‐(2‐aminoethyl) ethanolamine
Authors: Mukherjee Satyajit , Bandyopadhyay Syamalendu S. , Samanta Amar N. 
Published: October 2018

AbstractIn this work, carbon dioxide solubility in N‐(2‐aminoethyl) ethanolamine (AEEA) activated aqueous benzylamine (BZA) solutions are studied using a stirred‐cell reactor in the temperature and pressure range of 313.15–333.15 K and 0.2–219 kPa, respectively. AEEA is a linear diamine with a primary and secondary amine groups, and BZA is a primary cyclic amine. The concentration of the aqueous blends used are (20mass% BZA + 10mass% AEEA), (24mass% BZA + 6mass% AEEA), and (28mass% BZA + 2mass% AEEA). Density and viscosity of unloaded aqueous amine blends are also measured in experimental temperature and concentration ranges and correlated using Joubian–Acree mathematical model. Model‐predicted density and viscosity data are in good agreement with experimental results showing 0.05% and 3.41% AAD, respectively. To correlate experimental vapor–liquid‐equilibrium data, Kent–Eisenberg (KE), artificial neural network (ANN), and soft models are used. Equilibrium constants of monocarbamate formation reaction of BZA and AEEA are regressed as a function of temperature and CO2 loading to fit the experimental data with KE model expression. KE model is also utilized to estimate the pH of CO2 loaded aqueous amine solutions. ANN model is found to predict CO2 solubility with better accuracy (1.56% AAD) in comparison of KE model (8.27% AAD) and soft model (15.5%). The CO2 absorption capacity of (20mass% BZA + 10mass% AEEA) solvent (~0.8 mol CO2/mol amine) is higher than that of monoethanolamine (~0.5 mol CO2/mol amine). Heats of absorption values of (BZA + AEEA) solvents (~25 kJ/mol CO2) predicted from Gibbs–Helmholtz relationship are found to be lower than that of MEA (~87 kJ/mol CO2) and PZ (~66 kJ/mol CO2).
Impact of chloroform exposures on reproductive and developmental outcomes: A systematic review of the scientific literature
Authors: Williams Amy Lavin , Bates Christopher A. , Pace Nelson D. , Leonhard Megan J. , Chang Ellen T. , DeSesso John M. 
Published: October 2018

AimsWe assessed the animal and epidemiological data to determine if chloroform exposure causes developmental and/or reproductive toxicity.Results and DiscussionInitial scoping identified developmental toxicity as the primary area of concern. At levels producing maternal toxicity in rats and mice, chloroform caused decrements in fetal weights and associated delays in ossification. In a single mouse inhalation study, exposure to a high concentration of chloroform was associated with small fetuses and increased cleft palate. However, oral exposure of mice to chloroform at a dose 4 times higher was negative for cleft palate; multiple inhalation studies in rats were also negative. Epidemiologic data on low birth weight and small for gestational age were generally equivocal, preventing conclusions from being drawn for humans. The animal data also show evidence of very early (peri‐implantation) total litter losses at very high exposure levels. This effect is likely maternally mediated rather than a direct effect on the offspring. Finally, the epidemiologic data indicate a possible association of higher chloroform exposure with lower risk of preterm birth (<37 weeks gestation).ConclusionsThe available animal data suggest that exposures lower than those causing maternal toxicity should be without developmental effects in the offspring. Also, most studies in humans rely on group‐level geographic exposure data, providing only weak epidemiologic evidence for an association with development outcomes and fail to establish a causal role for chloroform in the induction of adverse developmental outcomes at environmentally relevant concentrations.