bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smoking behavior and the risks of tumor recurrence and progression in patients with non‐muscle‐invasive bladder cancer
Authors: Kiebach Joann , Beeren Ivy , Aben Katja K. H. , Witjes J. Alfred , van der Heijden Antoine G. , Kiemeney Lambertus A. L. M. , Vrieling Alina 
Published: November 2024

AbstractStudies on the relationship of cigarette smoking with the risks of recurrence and progression of non‐muscle‐invasive bladder cancer (NMIBC) are inconsistent and prospective data are scarce. Therefore, we aimed to assess the association of smoking behavior with risks of NMIBC recurrence and progression. We used data of the prospective multi‐center cohort study UroLife, including 1495 patients with NMIBC who reported information on smoking at 6 weeks post‐diagnosis (baseline; reflecting present and pre‐diagnosis). This included smoking status (also based on reporting 3 months post‐diagnosis), intensity, duration, pack years, and time since smoking cessation, if applicable. Hazard ratios and 95% confidence intervals (CIs) for risks of first recurrence, multiple recurrences, and progression were computed using multivariable proportional hazards regression models. During a total median follow‐up period of 4.6 years, 517 patients developed ≥1 recurrence and 163 had progression. Higher versus lowest categories of smoking intensities and pack years up to baseline were significantly associated with a higher risk of first recurrence. No significant linear associations were found, except for smoking intensity among BCG‐treated patients (per 10 cigarettes/day increase: HR 1.23, 95%CI 1.02, 1.48). No associations for smoking status, duration, and time since cessation were observed. Analyses of multiple recurrence risk showed comparable results. Regarding progression risk, no consistent associations were found. In conclusion, heavier smoking was associated with higher recurrence risk, particularly among BCG‐treated patients. This may be attributable to persistent damage through its carcinogenic compounds. Given the mixed results across different exposures, the effect of smoking behavior on NMIBC prognosis remains unclear.
A rare case of retroperitoneal recurrence as squamous cell carcinoma 10 years after nephroureterectomy
Authors: Uehara Koichiro , Onuki Tatsuaki , Ishibashi Yukari , Matsunuma Sayuki , Ishida Hiroaki , Kumagai Jiro , Murakami Takayuki 
Published: November 2024

IntroductionLocal recurrence for upper tract urothelial carcinoma typically occurs within 2 years post‐surgery. We report a rare case of retroperitoneal recurrence as squamous cell carcinoma 10 years after nephroureterectomy.Case presentationA 67‐year‐old female was referred to our urology department for a left ureteral tumor. The surgical specimen of the laparoscopic left nephroureterectomy revealed urothelial carcinoma at the pT3 stage. Ten years post‐nephroureterectomy, magnetic resonance cholangiopancreatography revealed a mass lesion in the left retroperitoneum, a computed tomography‐guided biopsy revealed squamous cell carcinoma. Despite suspected distant metastases of other organ tumors, examinations such as digestive endoscopy and bronchoscopy did not reveal any tumor lesions. The patient was diagnosed with recurrent invasive urothelial carcinoma as a pathological feature of squamous cell carcinoma.ConclusionThe decision‐making process for treating malignant tumors, such as in cases with recurrence as squamous cell carcinoma, can be challenging.
Developmental Imaging of Radish Sprouts Using Dynamic Optical Coherence Tomography
Authors: Lim Yiheng , Kojima Shumpei , Mukherjee Pradipta , El‐Sadek Ibrahim Abd , Makita Shuichi , Yasuno Yoshiaki 
Published: November 2024

ABSTRACTThe germination process of radish sprouts was investigated in detail using volumetric dynamic optical coherence tomography (OCT). Dynamic OCT involves the sequential acquisition of 16 OCT images and subsequent temporal variance analysis of each pixel, enabling non‐invasive visualization of the cellular and tissue activities of plants. The radish sprouts were longitudinally investigated for up to 12 days, and changes in morphology and dynamic OCT image patterns were observed as the plants developed. The dynamic OCT signals in the vessels and growing roots were relatively high in the early stage of germination and decreased as the tissue matured. These results suggest that dynamic OCT is sensitive to water and nutrient transport as well as cellular activities associated with plant growth.
Impact of Overweight on Renal Prognosis in Malignant Hypertension Patients With Thrombotic Microangiopathy
Authors: He Feng , Zhou Zhaocai , Zhao Sheng , Li Wenchuan , Lian Xingji , Yu Jianwen , Lin Zhengmei , Song Zhi , Chen Wei , Li Jianbo 
Published: November 2024

ABSTRACTObjectiveOverweight and obesity is a risk factor for hypertension. Malignant hypertension (MHT) is the most severe form of hypertension, and thrombotic microangiopathy (TMA), one of its complications, has been linked to significant renal outcomes. However, the impact of overweight and obesity on renal prognosis in MHT patients with TMA is not well understood.MethodsThis was a prospective cohort enrolled 288 MHT patients with renal TMA from 2008 to 2023. The clinical and histopathological characteristics were recorded based on body mass index (BMI, < 25 and ≥ 25 kg/m2). The outcome was the incidence of kidney failure. The associations of BMI with kidney failure were examined in logistic regression models.ResultsAmong 288 patients, 180 (62.5%) progressed to kidney failure, including 113 (68.5%) patients with BMI < 25 kg/m2. Participants with obesity had higher levels of hemoglobin, estimated glomerular filtration rate and C3, but lower levels of serum creatinine and IgA nephropathy. BMI ≥ 25 kg/m2 was associated with a better outcome of kidney failure in MHT patients with TMA (odd ratios [ORs]: 0.49 [95% confidence interval (CI): 0.27–0.91], p = 0.025). Male, uric acid, onion skin lesions, and global sclerosis ratio were correlated with higher risk of kidney failure; serum albumin and treatment with renin–angiotensin system blockers were related to lower risk of kidney failure.ConclusionsIn MHT patients with renal TMA, normal‐weight rather than overweight was found to associate with a worse renal prognosis. Management efforts for MHT may be directed toward controlling body weight within a reasonable range for patients.
Enhancing research methods: The role of systematic and scoping reviews in orthopaedics, sports medicine and rehabilitation
Authors: Prill Robert , Królikowska Aleksandra , Enes Kayaalp M. , Ramadanov Nikolai , Karlsson Jon , Hirschmann Michael T. 
Published: November 2024

AbstractEfforts to improve research standards in orthopaedics, sports medicine, physical therapy, and rehabilitation are ongoing. Rrehabilitation andomized Controlled Trials (RCTs) are widely regarded as the gold standard for the collection of primary data. Similarly, systematic reviews, due to their methodological rigor, have become the gold standard for evidence synthesis in medicine. However, while narrative reviews often lack scientific rigor and systematic reviews are not suited to addressing all research questions, other robust review formats are necessary. When the outcomes of interest are unknown or difficult to define in advance, scoping or mapping reviews are more appropriate, as they can address a broader range of questions within the field. Consequently, it is essential to establish rigorous methods for conducting scoping reviews across medical disciplines.
Patient‐reported outcome measures following individualised TKA are not affected by the degree of preoperative coronal varus or valgus laxity
Authors: Sappey‐Marinier Elliot , Bouguerra Margot , Chapuis Romain ,   ReSurg, Aït‐Si‐Selmi Tarik , Bonnin Michel P. 
Published: November 2024

AbstractPurposeTo determine whether there is a correlation between preoperative coronal varus or valgus laxity and patient‐reported outcome measures (PROMs) 2 years after individualised total knee arthroplasty (TKA).MethodsRecords of 150 consecutive patients who received individualised TKA were retrospectively analysed, and 126 with complete pre‐ and postoperative data were included. Preoperative coronal varus and valgus stress radiographs (15 N load) were taken using a telos stress device with the knee in 5°–10° of flexion. Varus stress angles were positive if the joint opened on the lateral side, and valgus stress angles were positive if the joint opened on the medial side. The sum of varus and valgus stress angles indicated total joint laxity. During surgery, cases that required tibial recuts to balance the joint were recorded. Patients completed three PROMs and rated their satisfaction. Correlations between laxity and PROMs were evaluated using Pearson's correlation.ResultsStress radiographs revealed varus stress angles of 6.3° ± 3.5° (range, −4.5° to 14.1°), valgus stress angles of 0.1° ± 3.7° (range, −8.0° to 10.9°), and the sum of the varus and valgus stress angle of 6.4° ± 3.3° (range, 0.1° to 17.1°). There were no correlations between laxity and PROMs: r < 0.160 for varus stress angle, r < 0.180 for valgus stress angle and r < 0.160 for the sum of stress angles. There were no statistically significant or clinically relevant differences in PROMs between knees without and those with tibial recuts.ConclusionPreoperative coronal varus or valgus laxity was not correlated with PROMs following individualised TKA at a minimum 2‐year follow‐up. Individualised TKA with personalised alignment enables adequate accommodation of a broad spectrum of preoperative coronal varus–valgus laxities.Level of EvidenceIV
Effects of Different Wheat Varieties on Soil Bacterial and Fungal Communities
Authors: Zhang Lei , Li Minghui , Cai Hua , Li Shuo , Shen Zhen , Li Xingchen 
Published: November 2024

ABSTRACTThe diversity and stability of soil microbial communities are indispensable components for maintaining the functions and services of agricultural ecosystems and play crucial roles in wheat production. However, the effects of different wheat varieties on soil microbial diversity, network complexity, stability, and assembly mechanisms remain largely unexplored. To bridge this research gap, we conducted field experiments in Chuzhou, China, to study the yield and soil microbial community composition of six different wheat varieties. The soil bacterial and fungal communities were investigated using high‐throughput sequencing of the 16S rRNA and ITS gene regions. Our findings indicated that, compared to common wheat, high‐yielding and disease‐resistant (HD) wheat increased both bacterial and fungal α‐diversity by regulating soil nitrogen and phosphorus concentrations, significantly affecting community structure (Adonis, p < 0.001). HD wheat significantly altered the co‐occurrence network patterns of soil microbial communities. Network analyses revealed that HD wheat increased the complexity of fungal networks while exhibiting the opposite trend for bacterial networks. However, both the bacterial and fungal networks demonstrated increased stability. Furthermore, HD wheat may increase microbial migration rates, influencing assembly processes by promoting stochastic processes in bacterial and fungal communities. Overall, this study provides valuable insights into the ecological functions and driving factors of soil microbes, offering information for the development of ecological management strategies to achieve sustainable wheat cultivation and improve soil quality. Furthermore, HD wheat significantly modified the co‐occurrence network patterns of the soil microbial communities. Network analysis revealed increased fungal network complexity in HD wheat, whereas bacterial networks showed the opposite trend. However, both the bacterial and fungal networks exhibited enhanced stability. Additionally, HD wheat likely increased microbial migration rates, influencing assembly processes by promoting stochastic processes in both bacterial and fungal communities. Overall, this study provides valuable insights into the ecological functions and driving factors of soil microbes, providing information for the development of ecological management strategies to achieve sustainable wheat cultivation and improve soil quality.
Variability of Soil Aggregate Disintegration During Splash Erosion Under Different Circumstances
Authors: Li Hairu , Liu Gang , Liu Ya , Han Yuqian , Liu Chang , Dan Chenxi , Shen Enshuai , Xia Xiaolin , Liu Dandan , Guo Zhen , Zhao Xining 
Published: November 2024

ABSTRACTThe duration of rainfall is a significant factor in the process of splash erosion. Nevertheless, there is a lack of comprehensive documentation regarding the extent and characteristic of soil aggregate disintegration resulting from raindrop impact during splash erosion. To examine the properties of the aggregate disintegration mechanism during various of splash erosion, three soil samples (S‐1, S‐2, and S‐3 labeled as the organic matter was 19.77, 31.70, and 26.83 g kg−1) were employed to simulated splash erosion under six durations of rainfall (5, 10, 15, 20, 30, and 40 min). Aggregates ranging in size from 1 to 5 mm were utilized in the preparation of test soils for different antecedent moisture contents (3%, 5%, 10%, and 15%). The result demonstrated that the slaking effect, as observed in the fast wetting of the Le Bissonnais method, is attributed to the sudden release of air entering the water, irrespective of the water immersion duration. Upon increasing moisture content, under fast wetting conditions, the mean weight diameter (MWD) values for S‐2 and S‐3 samples increased from 1.25 and 1.31 to 1.85 and 1.61, respectively. Subsequently, at a moisture content of 10%, the MWD decreased to 1.84 and 1.49 for S‐2 and S‐3 samples, respectively. In contrast, S‐1 sample exhibited an increasing trend from 0.34 to 0.93. The sensitivity of aggregates to disintegration from slaking (RSI) decreased by 0.58, 0.43, and 0.29, while mechanical impact (RMI) decreased by 0.23, 0.11, and 0.08 with increasing moisture content, respectively. The rate of splash erosion for the S‐1 sample exhibited an initial increase followed by a subsequent decrease as the duration of rainfall increased. The S‐1 sample, with the lowest organic matter content, exhibited the highest content of microaggregate content (< 0.25 mm) of splashed particles (referring to soil particles transported out of the splash area by raindrops), ranging from 31.62% to 65.57%. The content of macroaggregate (> 0.25 mm) in the residual soil (indicating soil particles that were left in the area affected by splashing) exhibited a gradual reduction as the duration of rainfall increased. As the soil reached saturation, the influence of physicochemical dispersion became more pronounced with the prolonged duration of rainfall. The forces of slaking and physicochemical dispersion predominantly disrupted > 1 mm aggregates, while the destruction of aggregates within the 0.25–1 mm range was insufficient. This study is valuable for understanding the splash erosion process and provides a scientific foundation for the improvement of soil erosion prediction models.
Application of Spectral Imaging and Vegetation Index in Latin American Coffee Production: A Systematic Mapping
Authors: Apraez Laura Sofia Caicedo , Pino Andrés Felipe Solis , Ossa Andres , Vasquez Carlos Iván , Solarte Juan David , Cabrera Efrén Venancio Ramos , Ruiz Saul Eduardo 
Published: November 2024

ABSTRACTCoffee production is a crucial economic, social, and cultural pillar in Latin America, facing numerous challenges, including integrating technological advancements such as multispectral imaging. This approach offers multiple advantages for coffee production; however, a knowledge gap in the domain is the need to methodologically review the available empirical evidence to delineate the field and the study region. Therefore, this systematic mapping aims to map the scientific corpus of multispectral imagery and vegetation index implemented in coffee production in the Latin American region. The study followed the PRISMA protocol; 42 primary studies were analyzed to identify key trends and research gaps. The main result of this research is that NDVI emerged as the most widely used spectral index, with applications in estimating critical biophysical parameters such as biomass and chlorophyll content. Other indices such as GNDVI, NDRE, and SAVI also proved valuable in assessing coffee plant health and development. There was an emerging trend to integrate multispectral imaging with machine learning techniques, promising greater accuracy in data interpretation. The study also revealed a concentration of research efforts in selected Latin American countries, particularly Brazil, indicating opportunities to expand research in other coffee‐producing regions. The study's main conclusion is that multispectral imaging, mainly through vegetation index, has emerged as a valuable tool for phenological monitoring and management of coffee production, offering several advantages over traditional methods. Finally, this review contributes to the existing knowledge base and identifies future research directions for applying multispectral imagery to sustainable coffee production in Latin America.
Effect of a tropical cyclone on the pelagic ecosystem of a continental shelf
Authors: Chen Chung‐Chi , Hsieh Chih‐hao , Cheng Yu‐Hsin , Huang Wei‐Jen , Chou Wen‐Chen , Shiah Fuh‐Kwo , Gong Gwo‐Ching , Chen Tzong‐Yueh 
Published: November 2024

AbstractThis study aimed to comprehend the effects of Typhoon Maria on the pelagic ecosystem in the southern East China Sea. Shipboard measurements were conducted at eight sampling stations before (2–4 d) and after (3–6 d) the typhoon, which enabled the evaluation of the potential impacts of the typhoon on this pelagic ecosystem, with particular focus on carbon dynamics. Following the typhoon's passage, there was a slight drop in sea surface temperature. The response of the variables to the typhoon, however, exhibited variations at different sampling stations. For further analysis, t‐tests compared variables, while type II regression assessed the linear correlation between two variables. Overall, during the post‐typhoon period, concentrations of nitrate, chlorophyll a, primary production, bacterial biomass and production, plankton community respiration, and abundance of large phytoplankton (> 2 μm) and the relative abundance of picophytoplankton among larger‐sized picoeukaryotes were higher compared to the pre‐typhoon period. The mean value of fugacity of CO2 was similar to or slightly lower than pre‐typhoon period. Although the typhoon‐induced vigorous primary production might have absorbed a significant amount of CO2, the decrease in fugacity of CO2 could have been offset by the plankton community respiration. The findings suggest that the typhoon enhanced physical disturbance and increased water column mixing, which, in turn, augmented nutrient availability and promoted plankton growth in the shallow water column. Overall, this study sheds light on the complex interactions between typhoons and marine ecosystems and highlights the importance of further investigating these phenomena to better understand their ecological implications.
Lubrication Prediction of Sphere‐Gradient Coated Half Space Interfaces
Authors: Gong Xiaoya , He Tao 
Published: November 2024

ABSTRACTFunctionally graded coating (FGC) has played a pivotal role in numerous engineering applications owing to its exceptional properties. This work proposes a novel elastohydrodynamic lubrication (EHL) model with FGC, in which the elastic deformation and stress are computed using influence coefficients (ICs) and discrete convolution‐fast Fourier transform (DC‐FFT) algorithm. Comparisons are made with homogeneous EHL solutions and finite element analysis (FEA) to validate its accuracy. The study systematically explores how coating elastic modulus, coating thickness and substrate elastic modulus influence contact and lubrication behaviours. The developed model is expected to establish a theoretical framework for FGC material design, enhancing the performance of friction pairs.
Numerical Thermal Analysis of Greased Rolling Bearing Considering Surface Topography and Plastic Deformation
Authors: Li Jiaqi , An Linxue , Huang Yuping , Li Zhenshun , An Ben , Guan Ben , Li Rui 
Published: November 2024

ABSTRACTIn numerical studies of grease lubrication, thermal effect is often neglected and surface plastic deformation is almost not considered. This paper has developed a deterministic thermal plasto‐elastohydrodynamic lubrication (PEHL) model for grease‐lubricated rolling bearing. The influence of tangent modulus, rheological index and texture orientation on lubrication characteristics and temperature rise is analysed. The results show that increasing the rheological index of grease and decreasing the wavelength factor are obviously positive for improving lubrication behaviour. Since surface plastic deformation in the EHL state is at nanoscale, film thickness, friction coefficient and temperature rise of solid surfaces decline slightly with the decrease of tangent modulus.
Mechanical Recycling of New and Challenging Polymer Systems: A Brief Overview
Authors: Titone Vincenzo , Botta Luigi , La Mantia Francesco Paolo 
Published: November 2024

AbstractPollution from plastics is a major issue in the current context, prompting the scientific community to focus its efforts on recycling these materials. Mechanical recycling emerges as the most popular due to its practicality and cost‐effectiveness. In fact, with the increase in environmental awareness, the adoption of new circular economy models, stricter regulations mandating disposal and recycling, and lower costs compared to other recycling techniques, this type of recycling is taking a predominant role over other method. However, the presence of a variety of products of different polymeric nature, the introduction of new biodegradable products, and the complexity of multilayer packaging combining different polymers, without concrete solutions for recycling create a heterogeneous range of materials that leaks into the environment. The scientific literature is actively addressing these challenges, and this review aims to explore the latest strategies for enhancing the mechanical recycling of new and challenging polymer systems. Specifically, it explores the recycling of materials originally designated for landfill, incineration or composting, focusing on advancements in management of these previously overlooked and problematic system. This underexplored perspective seeks to offer new insights and innovative solutions that can transform polymer waste management and advance more sustainable recycling practices.