bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rational use of Computed Tomography Scan head in the Emergency Department of a high volume tertiary care public sector hospital
Authors: Nishtar Tahira , Ahmad Tabish , Noor Nosheen , Muhammad Fayaz 
Published: March 2019

Objective: To emphasize the rational use of Computed Tomography (CT) head in emergency department (ED) of a high volume tertiary care hospital.
Methods: This retrospective observational study was conducted in Radiology Department of Medical Teaching Institute Lady Reading Hospital (MTI-LRH), Peshawar, Pakistan from November 1st 2017 to 31st January 2018. Patients of all ages and both genders presenting to the emergency department with post traumatic and non-traumatic indications for emergency CT head scan were included in the study. The imaging was performed on GE 16 multi slice Optima CT system. The imaging protocol included slice thickness of 3-5mm, non-contrast study for cases of head trauma or suspected stroke. Where needed intravenous contrast was administered e.g. to exclude meningitis in patients presenting with severe headache. Patients undergoing CT examination for regions of the body other than head and brain were excluded from the study as their number was insignificant. Reporting was done on PACS and results analyzed using latest SPSS version.
Results: Out of 4284 CT scans performed in emergency department 90.8% were CT head (3893). Among 3893 CT scan head done in ED, 2581 cases were reported normal (66.29%), while 1312 cases had positive findings (33.7%), including post traumatic and non-traumatic.
Conclusion: Misuse of CT head is common especially in an emergency setting. Emergency physicians should be encouraged to obtain a detailed history and perform a thorough physical examination with reference to internationally standardized guidelines, while ordering CT scan.
How to cite this:Nishtar T, Ahmad T, Noor N, Muhammad F. Rational use of Computed Tomography Scan head in the Emergency Department of a high volume tertiary care public sector hospital. Pak J Med Sci. 2019;35(2):302-308. doi: https://doi.org/10.12669/pjms.35.2.719
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Treatment options for benign prostate enlargement
Authors: Vlotman-Novinuk Deidre 
Published: March 2019

Benign prostate enlargement or benign prostatic hyperplasia is a very common condition in men as they get older. It is the most common cause of lower urinary tract symptoms (LUTS) in men. LUTS can significantly affect quality of life.Symptoms include frequent urination, a weak stream, incomplete bladder emptying, hesitancy to urinate, dribbling after urination, nocturia, urinary tract infections and urinary retention. Some men may be able to manage their symptoms with lifestyle changes and monitoring; however, many need treatment.Treatment depends on the individual and what impact his symptoms are having on his wellbeing. Treatment may include drugs, such as alpha-adrenergic blockers and 5-alpha-reductase inhibitors, or surgical intervention. Surgical procedures include transurethral resection of the prostate, laser, prostate artery embolisation, UroLift, water vaporisation and water jet ablation. However, all treatments cause side effects. It is important that the patient is at the centre of care and makes an informed decision about his treatment with the support of his health professional.
To prescribe or not to prescribe: enhancing safety in remote prescribing
Authors: Shepherd Alison Burton 
Published: March 2019

From time to time, it may be appropriate to use a telephone, or other non-face-to-face medium to prescribe medicines and treatment for patients. Non face-to-face media include telephone, fax, email, video link, or websites. This concept is known as remote prescribing and refers to prescribing for patients who are physically ‘remote’ or not in the same vicinity as the clinician ( Broadhead, 2011 ). Secondly, the term can also refer to an area of the UK described as being geographically ‘remote’, where direct face-to-face access to healthcare can be poor ( General Medical Council, 2017 ). Remote prescribing has been described as an important facility in healthcare, providing patients with greater accessibility to their medications and treatment ( Griffiths, 2018 ). However, remote prescribing is only acceptable in exceptional circumstances. The aim of this article is to identify and discuss clinical situations in which remote prescribing is acceptable, with an onus on safety. Broadhead (2011) proposes that the medical guidance for remote prescribing is analogous for other health professionals, including nurses and midwives who prescribe remotely using different forms of technology. Therefore, these guidelines will be referred to throughout this article.
Single-Cell Genomics
Authors: Paolillo Carmela , Londin Eric , Fortina Paolo 
Published: March 2019

AbstractBACKGROUNDSingle-cell genomics is an approach to investigate cell heterogeneity and to identify new molecular features correlated with clinical outcomes. This approach allows identification of the complexity of cell diversity in a sample without the loss of information that occurs when multicellular or bulk tissue samples are analyzed.CONTENTThe first single-cell RNA-sequencing study was published in 2009, and since then many more studies and single-cell sequencing methods have been published. These studies have had a major impact on several fields, including microbiology, neurobiology, cancer, and developmental biology. Recently, improvements in reliability and the development of commercial single-cell isolation platforms are opening the potential of this technology to the clinical laboratory.SUMMARYIn this review we provide an overview of the current state of single-cell genomics. We describe opportunities in clinical research and medical applications.
Documentación del Conocimiento Tecnológico y Pedagógico del Contenido, de un profesor de química ejemplar durante la implementación de un objeto de aprendizaje
Authors: Candela Rodríguez Boris Fernando 
Published: March 2019

Este estudio tuvo como propósito central documentar el conocimiento tecnológico y pedagógico del contenido de un profesor de química ejemplar cuando implementa el objeto de aprendizaje "cuando utilizamos diferentes unidades de concentración". Esta fue una investigación cualitativa mediante la modalidad de estudio de caso. Con el fin de dar confiabilidad a los resultados, los datos fueron recogidos a través de fuentes documentales como relatos, videos de las clases, observación no participante y trabajos de los estudiantes. Esta investigación produjo una gran cantidad de información que fue analizada desde la perspectiva de la teoría fundamentada, de lo cual se generaron cuatro categorías, a saber: 1) la pedagogía general, en conjunción con las habilidades lingüísticas y las relaciones cuantitativas median la comprensión de las unidades de concentración; 2) la enseñanza del tópico solubilidad, un medio para desarrollar las competencias que demanda la actual sociedad del conocimiento; 3) el principio de la intertextualidad, elemento fundamental para representar el tópico de los objetos de aprendizaje; y 4) la enseñanza de unidades de concentración en relación con la evaluación formativa y las pruebas de naturalezaestandarizada. El desarrollo teórico de estas categorías se tradujo en los relatos de experiencias profesionales y pedagógicas (PaP-eR), que representaron los procesos de razonamiento y acciones pedagógicas realizadas por el profesor ejemplar durante la implementación del objeto de aprendizaje.
A tradição de pesquisa segundo Laudan en educação em espaços não formais num evento de ensino de ciências
Authors: Seiffert Santos Saulo Cezar , Borin da Cunha Márcia 
Published: March 2019

A pesquisa em Educação Não Formal em Ciências tem crescido no Brasil, principalmente em eventos. No Encontro Nacional de Pesquisadores em Educação em Ciências − ENPEC essa discussão está presente em uma linha temática desde 1997, e recebe trabalhos de todo o país. Assim, aqui o questionamento é se essa temática possui tradição própria de pesquisa nos termos de Larry Laudan, na obra “O Progresso e seus Problemas: rumo a uma teoria do crescimento científico” e se possui diferenças em relação aos outros campos de pesquisa na Educação em Ciências. Diante disso, o objetivo da pesquisa é analisar os trabalhos do ENPEC nas edições de 2011 a 2017 com base no Modelo Reticulado de Racionalidade − MRR de Laudan. Foram encontrados 114 trabalhos com os descritores “não formal”. A pesquisa é de cunho qualitativo e seus dados são tratados pelos pressupostos da análise de conteúdo com a técnica análise categorial temática com base nas categorias do MRR. O uso dos indicadores junto às categorias métodos, teorias e fins/metas possibilitou verificar uma grande diversidade de trabalhos, públicos, métodos e reflexões. Foi, contudo, verificada em poucos trabalhos a influência museológica para a educação em ciências, mas uma lógica própria nessa temática denominável de Tradição em Educação Não Formal em Ciências com os campos de Enriquecimento Cultural, Complementaridade Escolar e Exploração de Alternativas Não Formais.
Conflicts and solidarities of the LGBTQ scene in St Petersburg
Authors: Onegina Elena V. 
Published: March 2019

Modern Russia shows increased problematization of LGBTQ communities and non-conventional gender identities in media and their almost complete exclusion from public space. However, the present study reveals that LGBTQ activists are solidarizing faced with symbolic, psychological and physical violence and pressure by the state, social institutions and the homophobic population. The empirical basis of the study is 14 interviews involving LGBTQ people and the overt observation. The scene approach highlights not only actors and practices within the scene but also the space where interactions take place. The author concludes that the St Petersburg LGBTQ scene represents heterogeneous community of organizations, initiatives, venues targeted at different groups of individuals with non-conventional sexual and gender identities. The LGBTQ scene is more likely to be seen as a reflexive, argumentative discussion of the most important community issues related to gender status, public actions, authorities, hierarchy and sexual and gender identities.
Acknowledgment. The paper is part of the project “Promoting the youth participation and social inclusion: analysis of innovative youth activism in Europe and Russia” implemented within the NRU HSE 2018 Fundamental Research Program.
Cryptozoospermia after treatment with clomiphene citrate following long-term use of intramuscular testosterone undecanoate depot injection (Nebido®)
Authors: Grubić Kezele Tanja 
Published: March 2019

Abstract

Objective
To illustrate the importance of treatment duration with intramuscular testosterone undecanoate (Nebido®) for the final spermatogenesis recovery after treatment cessation. Also, to show a subsequent poor efficacy of the selective estrogen receptor modulator (SERM) clomiphene citrate (CC) in treating steroid-induced azoospermia following Nebido® cessation and describe that initial oligozoospermia, existing before starting Nebido®, largely contributes to that treatment outcome.

Methodology
Setting: Department of Human Reproduction and Department of Endocrinology, Clinical Hospital Center Rijeka, Rijeka, and Department of Endocrinology, Clinical Hospital Center Sestre milosrdnice, Zagreb, Croatia. Patient: A male patient having been diagnosed with primary hypogonadotropic hypogonadism, oligozoospermia and low testosterone (T) level, was treated with intramuscular testosterone undecanoate (TU) depot 1 g (Nebido®) to prevent further progression of testosterone deficiency symptoms (low mood, energy and concentration, fatigue, muscle weakness). Interventions: Stopping Nebido® and treatment with CC 50 mg per day 5 days per week for 3–6 month to recover spermatogenesis. Main outcome measures: T levels and semen analyses.

Results
Semen analyses did not return to values before taking Nebido® 1 year after cessation nor after 3 months of treatment with CC. Values of T, follicle stimulating hormone (FSH) and luteinizing hormone (LH) dropped even more than before starting Nebido®, after 1 year of cessation.

Conclusions
Here we describe a case of initially idiopathic gonadal failure with subsequent secondary gonadal failure and infertility resulting from testosterone replacement therapy (TRT) treatment, and poor spermatogenesis recovery outcome of CC used post Nebido® cessation.
On a problem of Hasse and Ramachandra
Authors: Koo Ja Kyung , Shin Dong Hwa , Yoon Dong Sung 
Published: March 2019

AbstractLetKbe an imaginary quadratic field, and let 𝔣 be a nontrivial integral ideal ofK. Hasse and Ramachandra asked whether the ray class field ofKmodulo 𝔣 can be generated by a single value of the Weber function. We completely resolve this question when 𝔣 = (N) for any positive integerNexcluding 2, 3, 4 and 6.
Postharvest Quality of Roses under Different Levels of Nitrogenous Compounds in Holding Solution
Authors: Hatamian Mansoure , Souri Mohammad Kazem 
Published: March 2019

Abstract
Nitrogen (N) forms and N levels can have a great impact on growth and quality of agricultural crops. Postharvest N treatments may also affect the quality of products. This study was conducted under laboratory conditions to evaluate the changes in postharvest quality characteristics of cut roses (Rosa hybrid cv ‘Utopia’) under different nitrogen concentrations of holding solution. Three nitrogen sources including ammonium sulfate, calcium nitrate and potassium nitrate at five concentrations (0, 5, 10, 15 and 20 mgL-1 N) were applied into vases with holding solution. The results showed that low ammonium (5 mg L-1) and high nitrate (20 mgL-1) resulted in the highest leaf SPAD values, whereas the lowest values were recorded for those stems treated with the two highest ammonium concentrations (15 and 20 mg L-1). Leaf and petal relative water contents (RWC) were significantly reduced by higher ammonium concentrations, while they were increased by increasing calcium nitrate and potassium nitrate concentrations in the vase holding solution. Leaf catalase activity was increased by the two lowest (5 and 10 mg L-1) and decreased by the two highest ammonium levels (15 and 20 mg L-1), and it was not affected by the two other nitrogen salts. Higher ammonium levels resulted in a significant increase in leaf proline concentrations and petal ion leakage, whereas nitrate concentrations reduced these two traits. A low concentration of ammonium (5 mg L- 1) increased flower vase life while higher ammonium concentrations reduced the trait. There was also an increasing trend in flower vase life with higher concentrations of both nitrate salts. Therefore, low ammonium or high nitrate levels in vase holding solution can improve vase life quality of cut roses.
Migraciones y diversidad funcional. Realidad invisible de las mujeres
Authors: Díaz Jimémez Rosa María , De la Fuente Robles Yolanda María , Muñoz Moreno Rocío 
Published: March 2019

Ante la invisibilidad de la diversidad funcional en los estudios migratorios y el tímido interés de las migraciones en los estudios sobre discapacidad, este trabajo tiene como objeto hacer visible la diversidad funcional, especialmente a las mujeres con diversidad funcional en los procesos migratorios. A partir del análisis del material bibliográfico se explora la producción científica sobre las mujeres con discapacidad migrantes mediante una revisión sistematizada del fenómeno. Se perfila cierta tipología de personas que interactúan con la discapacidad y la migración: personas con discapacidad que realizan la migración; personas adultas que han accedido a la situación de discapacidad después del proceso migratorio o asociado al mismo y menores que acompañados por sus familias migran para buscar mejores sistemas de protección social que apoyen su discapacidad.
ANALYSIS OF 3D SEMI-ELLIPTICAL CRACK ON REACTOR PRESSURE VESSEL WALL WITH LOAD STRESS AND CRACK RATIO
Authors: Susmikanti Mike , Himawan Roziq , Hartini Entin , Rokhmadi Rokhmadi 
Published: March 2019

Reactor Pressure Vessel (RPV) wall is an important component in the Nuclear Power Plant (NPP). During reactor operation, RPV is subjected to high temperature, pressure, and neutron exposure. This condition could lead to RPV structure failure. In order to assure the integrity of RPV during the reactor lifetime, it is mandatory to perform a structural integrity assessment of RPV by evaluating postulated crack in RPV. In the previous study, the crack has evaluated in 2-D. However, 3-D analysis of semi-elliptic crack shape in the surface of the thick plate for RPV wall using SA 508 Steel is yet to be analyzed. The objective of this study is to analyze and modeling the evaluation in variation crack ratio with some load stress in 3-D. The Stress Intensity Factor (SIF) and J-integral are used as crack parameter. The J-Integral were calculated using MSC MARC MENTAT based on Finite Element Method (FEM) for obtaining the SIF value. The inputs are a crack ratio, load stress, material property, and geometry. The modeling of SIF value and goodness of fit are using MINITAB. The fracture condition could be predicted in comparison to the SIF value and fracture toughness. For the load stress 70 MPa and 80 MPa, with a crack ratio 0.25, 0.33 and 0.5, the material on RPV wall will in fracture condition.Keywords: Semi elliptic surface crack, 3-dimension, reactor pressure vessel, elastic-plastic fracture mechanics, J-integral
RELIABILITY ANALYSIS OF PRIMARY AND PURIFICATION PUMPS IN RSG-GAS USING MONTE CARLO SIMULATION APPROACH
Authors: Hartini Entin , Adrial Hery , Pujiarta Santosa 
Published: March 2019

Reliability and maintenance play an important role in ensuring successful operation of a system. Reliability analysis is often used to determine the probability whether or not a system is functioning. However, limited available data and information are causing uncertainties and inaccuracies on component parameters. The purpose of this study is to conduct component/system reliability analysis using Monte Carlo simulation-based method. This method enables us to estimate the reliability of components/systems including parameter uncertainty and imprecision. It is also useful to predict and evaluate maintenance decisions related to reliability. Monte Carlo method employs random number generation based on the probability of the distribution of processed data, of which then validated with real available data to ensure the simulation condition is relatively similar to real-life condition. The data used in this research is failure data on RSG-GAS components/systems for core configuration number of 81 to 95, accumulated from year 2013 to 2018. The results show that reliability values of components JE01/AP01-02 on TTF 233.619 is 0.579 while for components KBE01/AP-01-02 in TTF 185.38 is 0.368.The component reliability value is 60%, which implies that maintenance may be performed after 225 days and 100 days for componentsJE01/AP01-02 and KBE01/AP01-02, respectively.Keywords: Reliability, Monte Carlo, Component damage, RSG-GAS
ÖZ BİLİNÇ PSİKO-EĞİTİM PROGRAMININ ÜNİVERSİTE ÖĞRENCİLERİNİN ÖZ BİLİNÇ DÜZEYLERİNE ETKİSİ
Authors: Alkal Ahmet , Akça Mehmet Şirin , Korkmaz Ozan 
Published: March 2019

Bu
araştırma, öz bilinç psiko-eğitim programının üniversite öğrencilerinin öz
bilinç düzeylerine etkisini incelemek amacıyla yapılmıştır. Araştırmanın
amacına uygun olarak
2x3’lük split-plot (deney-kontrol grubu x ön-test/son-test/izleme-testi) faktöriyel
desen kullanılmış, seçkisiz olarak 10’ar kişilik deney ve kontrol grupları
oluşturulmuştur. Deney grubundaki öğrencilere, araştırmacılar tarafından
geliştirilen her biri 90 dakika süren 10 oturumluk öz bilinç psiko-eğitim
programı uygulanmıştır. Kontrol grubundaki öğrencilere herhangi bir uygulama
yapılmamıştır. Katılımcıların öz bilinç
düzeyleri ‘Öz Bilinç Ölçeği’ ile belirlenmiştir. Verilerin analizinde, karışık
desenler için iki Faktörlü ANOVA analizi ve farkın kaynağını belirlemek
amacıyla da Benferroni testi kullanılmıştır. Yapılan analizler sonucunda,
uygulanan psiko-eğitim programının deney grubunda bulunan katılımcıların öz
bilinç düzeylerini yükseltmede etkili olduğu bulunmuştur. Ayrıca on hafta sonra
alınan izleme ölçümlerinde, bu etkinin öz bilinç bağlamında devam ettiği
sonucuna ulaşılmıştır. Bu bulgular alan yazın doğrultusunda tartışılmış, alanda
çalışan uzmanlar için ve ilerde yapılacak çalışmalara yönelik önerilerde
bulunulmuştur.
Elevated LVEDP, Chronic Pulmonary Oedema and Valve Disease
Authors: Banerjee Prithwish 
Published: March 2019

As part of ageing and with increased longevity of older people there has been a rise of those with left ventricular diastolic dysfunction (LVDD) and increased left ventricular end diastolic pressure (LVEDP). Comorbidities like hypertension, diabetes, chronic kidney disease, coronary artery disease and others appear to be contributing to this . Chronic interstitial pulmonary oedema may be a part of the presentation of those with elevated LVEDP/LVDD. Progressive valvular heart disease may also complicate the picture and make clinical decision-making difficult. This case report discusses these issues.
Yatay Borularda Türbülatörlerin Isı Transferine Olan Etkisinin Deneysel Araştırılması
Authors: KARAGÖZ Şendoğan , ÇİLTAŞ Sibel , YILDIRIM Orhan , ERDOĞAN Sadık 
Published: March 2019

Bu çalışmada, boru içerisine türbülans
oluşturacak kanatçıklar yerleştirilerek boş boru ile kıyaslanmıştır. Üç farklı
kanatçık arası mesafede (Sy=101, 216, 340) ve üç farklı kanatçık
açısına(α=0o, 45o,
90o) sahip 9 türbülatör, üç farklı Reynolds
sayısında (Re) kullanılmıştır. Bu türbülatörlerin ısı transfer performansı ve
sürtünme karakteristikleri deneysel olarak incelenmiştir. En yüksek hız
değerinde Nu sayısındaki en yüksek artış Sy =101mm kanatçık arası
mesafede ve α = 90° kanatçık açısında elde edilmiştir. Kanatçık
arası mesafenin artmasıyla Nu sayısında azalma olduğu görülmüştür. Sy
mesafesi en az olan türbülatör bütün Re sayılarında en yüksek Nu sayısına
sahiptir. Nu sayısı açısından sırama yapıldığında; Sy(10) &gt; Sy(5)
&gt; Sy(3) olduğu gözlemlenmiştir.
Bu türbülatörlerin kanatçık arası mesafesinin (Sy) ve
kanatçık açılarının (α), Nu sayısına etkisi olduğu yapılan çalışmalarla
görülmüştür.
Team Approach: Guideline-Based Management of Skin Injury in Individuals with Myelomeningocele
Authors: Bradko Viachaslau , Hill Jaclyn , Castillo Heidi , Castillo Jonathan 
Published: March 2019

» As many as 100,000 people in the United States live with myelomeningocele.» Due to recent advancement in treatment, about 75% of children with myelomeningocele reach adulthood. Up to 77% of patients with spina bifida report skin-breakdown issues annually.» The management of patients who have myelomeningocele requires a multidisciplinary approach that should begin early in life and should aid in transitions through health-care settings across the lifespan. Education on the prevention of skin injury must be repetitive, frequent, culturally appropriate, and ongoing.» The development of a team approach to evidence-based prevention, education, and treatment is imperative, with the goal of reducing skin breakdown and increasing self-management among individuals with myelomeningocele.