bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep sedation versus minimal sedation during endobronchial ultrasound transbronchial needle aspiration
Authors: Conte Sergio C. , Spagnol Giulia , Confalonieri Marco , Brizi Beatrice 
Published: January 2019

The sedation plays an important role in the endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) procedure. The sedation can be Minimal (anxiolysis), Moderate (conscious sedation) or Deep. The ACCP guidelines suggest that moderate or deep sedation (DS) is an acceptable approach. In fact, several studies compare moderate versus deep sedation, but no study has been carried out to compare deep sedation versus minimal. We carried out a retrospective study to compare the Deep versus Minimal sedation (MiS) in patients undergoing EBUS-TBNA. The primary end point was the diagnostic accuracy. The secondary end points were adequacy and sensitivity. We evaluated the LN size sampling, procedural time, complications and patient tolerance. Thirty-six patients underwent EBUS-TBNA, 16 under DS and 20 under MiS. The overall diagnostic accuracy for correct diagnosis was 92.9% in DS group and 94.1% in MiS group (p=0.554). Sample adequacy, defined as the percentage of patients with a specific diagnosis by EBUS-TBNA, was 87.5% (14 of 16) and 85% (17 of 20) for the DS group and MiS group, respectively, (p=0.788); the sensitivity was 92.9% in the DS group (95% CI, 73-100%) and 92.9% in the MiS group (95% CI, 77-100%) (p=0.463). There were no major complications in either group. Minor complications were 4 in MiS and 1 in DS (p=0.355). The patients in the MiS group recalled the procedure more often compared to the other group (p=0.041). The majority of the patients would agree to undergo the same procedure again in the future in both groups (p=0.766). In our experience EBUS-TBNA performed under MiS has comparable accuracy, adequacy, sensitivity, complications and patient satisfaction to DS, even if the sample was small. Future prospective multicenter studies are needed to confirm our results.
Pasteurellose de la Poule et du Lapin. Essais de vaccination et de contamination
Authors: Paille R. 
Published: January 2019

Sur la Poule et sur le Lapin, nous avons recherché s’il était possible d’obtenir pratiquement, avec la culture tuée d’une souche choléra, une résistance assez nette pour que le produit puisse être conseillé. Le matériel vaccinal contient 30 milliards de corps bactériens par centimètre cube. A cette dose, en péritoine, il tue le Cobaye en seize heures de moyenne, par intoxication aiguë.
Les Poules qui reçoivent ce matériel dans diverses conditions succombent, comme les témoins, à l’épreuve sévère par inoculation. A l’épreuve de contamination par séjour prolongé en milieu naturellement ou 'artificiellement infecté, elles ne témoignent non plus d’aucune résistance vaccinale acquise.
L’expérience de contamination, poursuivie pendant deux mois, prouve que le choléra est beaucoup moins contagieux, pour la Poule qu’on l’admet habituellement. Ainsi s’explique le succès apparent de certains vaccins commerciaux.
Le Lapin se comporte tout autrement que la Poule ; il s’immunise beaucoup plus facilement et beaucoup mieux.
L’expérience de contamination, conduite comme chez la Poule, confirme que la pasteurellose est très contagieuse pour le Lapin : tous les animaux neufs contractèrent la maladie sous la forme aiguë, septicémique. Chez les vaccinés aussi la contagion s’effectua, mais avec des conséquences tout autres que pour les animaux neufs. L’un d’eux, il est vrai, succomba, mais à la forme subaiguë — malgré que l’infection eût été déterminée par la Pastourelle hypervirulente — preuve de la résistance qu’il avait acquise sous l’influence de la vaccination. Les deux autres résistèrent parfaitement ; eux non plus n’avaient cependant pas échappé à la contagion, mais elle n’avait fait que renforcer la résistance vaccinale, ainsi que le prouva leur comportement devant une épreuve très sévère par inoculation.
Travail de l’Institut Mérieux (Lyon).
Anticorps et protéines, leurs liaisons dans le sérum antisymptomatique
Authors: Paille R. 
Published: January 2019

Partant d’un sérum antitoxique surtout : le sérum antisymptomatique, obtenu d'un Cheval en puissance d’hyperimmunité maximale, nous avons recherché lés liaisons qu’entretiennent, avec les anticorps spécifiques, les protéines sériques séparées par M. Piettre avec sa méthode à l’acétone aux basses températures.
La recherche de l’anticorps immunisant nécessita une centaine de Cobayes mâles (600 g.). — Il en résulte que l’immunisine est liée aux deux principales protéines, mais dans des proportions très différentes. Par rapport au sérum entier, l’albumine supporte au moins 80 p. 100 du pouvoir préventif ; ta globuline, 10 p. 100 environ.
L ’anticorps floculant fut recherché sur des cultures jeunes (13 heures). Il en résulte concernant l’antigène H ou flagellaire, que l’agglutinine est supportée, presque tout entière, par la globuline.
REINFORCED MECHANICAL PROPERTIES OF FUNCTIONALIZED SILICA AND EGGSHELL FILLED GUAYULE NATURAL RUBBER COMPOSITES
Authors: Ren Xianjie , Geng Yang , Soboyejo Alfred B. O. , Cornish Katrina 
Published: January 2019

ABSTRACT
Replacing synthetic fillers, which are commonly used to reinforce rubber, with bio-fillers has potential to improve the sustainability of rubber products. Eggshell (ES) (a powder with a maximum particle diameter of 9.4 μm and a median of 1.1 μm) was added to guayule natural rubber (GNR) composites to partially or fully replace bifunctionally silanized, high surface area, precipitated silica (BSS). The mixing energy consumption, mechanical properties, cross-link density, filler dispersion and final particle size, fracture surface morphology, and dyeability of GNR composites were characterized. ES filler effectively reinforced vulcanized GNR compared with unfilled vulcanized GNR. Energy consumption, modulus at 300% strain (M300), and hardness generally decreased with increasing ES fraction (decreasing BSS), but tensile strength, gel fraction, and elongation at break increased even where cross-link density and M300 were similar. Thus, composite cross-link density was not solely influenced by silane content as the ratio and loading of ES and BSS changed. The production of the composites reduced particle size to submicron size. Even a small amount of ES improved the dispersion of BSS filler particles in the composites and hence the mechanical properties. The contributions of the two fillers to the composite properties are explained. Linear mixed models were built to predict the mechanical properties of a broader range of GNR–ES–BSS composites, and r2 (the quality of the model predictability) was above 0.9 for all models. ES filled GNR, with or without BSS, can be dyed different colors for specific applications. The lower-cost, renewability, dyeability, and excellent performance of ES–GNR composites addresses the need for sustainable rubber products with low carbon footprint.
A Q-based approach to clausal ellipsis: Deriving the preposition stranding and island sensitivity generalisations without movement
Authors: Griffiths James 
Published: January 2019

This paper argues that the meaning of a clausal ellipsis site can only be recovered from a syntactically derived question, regardless of whether this question is explicitly uttered or is merely pragmatically inferred. This entails that the meaning of a clausal ellipsis site cannot be recovered from an inferred question q in a language L if q is syntactically ill-formed in L. I demonstrate that this restriction on recoverability can account for Merchant’s (2001; 2004) Preposition-Stranding Generalisation and for the observation that fragments appear to be sensitive to syntactic islands (Merchant 2004; Abels 2011; Barros et al. 2014; 2015) without any mention of whether remnants of clausal ellipsis themselves undergo movement. Because there is no need to stipulate that remnants themselves undergo (often exceptional) movement under this approach, a theory of clausal ellipsis modelled on Cable’s (2010) Q-based analysis of wh-questions is developed that permits non-pronunciation “around” designated phrases. This approach is shown to be preferred on many occasions to the predominant movement-based analysis (Merchant 2004), which is too restrictive and must frequently resort to the notion of ellipsis repair.
Strafrecht door de ogen van een witteboordencrimineel
Authors: Huisman Wim , Lesmeister Dennis 
Published: January 2019

Criminal justice through the eyes of a white-collar offender
Internationally, research on the experiences of white-collar offenders with the criminal justice system and the consequences of prosecution and conviction is scarce. Such research becomes more relevant, as the response to white-collar crime has become more punitive and more offenders are convicted. This paper presents the experiences of the co-author as a convicted white-collar offender as an autobiographical case-study. In this cases study, the consequences and experiences during four phases (investigation, prosecution, sentence-execution and post-sentencing) are analysed on four live-domains: health, private life, social life and professional life. Such an approach could be a blueprint for further and more systematic study of the experiences with and consequences of criminal justice for white-collar offenders. Such study can shed light on the effects and actual achievement of goals of punishment for white-collar crime.
A Review of Current Challenges in Colorectal Cancer Reporting
Authors: Dawson Heather , Kirsch Richard , Messenger David , Driman David 
Published: January 2019

Context.—Pathologic assessment of colorectal cancer resection specimens plays an important role in postsurgical management and prognostication in patients with colorectal cancer. Challenges exist in the evaluation and reporting of these specimens, either because of difficulties in applying existing guidelines or related to newer concepts.Objective.—To address challenging areas in colorectal cancer pathology and to provide an overview of the literature, current guidelines, and expert recommendations for the handling of colorectal cancer resection specimens in everyday practice.Data Sources.—PubMed (US National Library of Medicine, Bethesda, Maryland) literature review; reporting protocols of the College of American Pathologists, the Royal College of Pathologists of the United Kingdom, and the Japanese Society for Cancer of the Colon and Rectum; and classification manuals of the American Joint Committee on Cancer and the Union for International Cancer Control.Conclusions.—This review has addressed issues and challenges affecting quality of colorectal cancer pathology reporting. High-quality pathology reporting is essential for prognostication and management of patients with colorectal cancer.
D’« Altazor » à Larva : le courant transformationniste en traduction
Authors: de Sart Amaury 
Published: January 2019

Le présent article porte sur les tendances traductives du courant transformationniste lié à la revue Change (1968-1983) à travers l’exemple d’un extrait du roman Larva de Julián Ríos traduit par Gérard de Cortanze. Cette traduction témoigne de nombreuses prises de liberté narratives et poétiques, conformément aux principes transformationnistes qui visent au détournement de la poéticité du texte original. Pour comprendre la position traductive de de Cortanze, sa traduction du poème « Altazor » de Vicente Huidobro et la préface qui l’accompagne, parues quelques années avant la traduction de Larva, ont servi de référence. L’une des particularités du projet de traduction de Larva réside dans le fait qu’il a été guidé par la traduction de poésie avant-gardiste. À partir de la perspective sociocritique d’Annie Brisset dans ses travaux sur la traduction d’« Altazor » (2006 ; 2011), cet article considère la traduction d’un extrait de Larva en lien avec le discours critique qui lui est contemporain.
Behind the Scenes of Inuit Curriculum Development in Nunavut, 2000–2013
Authors: McGregor Heather E. , McGregor Catherine A. 
Published: January 2019

In this article we examine the provision of curriculum in Nunavut between 2000 and 2013. During this time the Government of Nunavut established a mandate to ensure all curriculum from Kindergarten through Grade 12 was founded onInuit Qaujimajatuqangit(IQ) and supported bilingualism. We describe how the Curriculum and School Services Division of the Department of Education undertook to fulfil this responsibility through unique, made-in-Nunavut curriculum development processes and products. We conclude by outlining the opportunities and challenges evident in the work of creating curriculum, teaching resources, and learning materials that centre Inuit knowledges, languages, and contexts.
Stratégies et équipements de la chasse au narval dans le fjord Inglefield (Groenland)
Authors: Drieux Christiane 
Published: January 2019

Fondé sur une enquête de terrain dans le nord-ouest du Groenland, cet article présente les stratégies et les équipements utilisés par les Inughuit chasseurs de narval dans la zone réglementée du fjord Inglefield au sud-est de Qaanaaq. Encore construit et utilisé actuellement dans la région de Qaanaaq, le kayak permet aux chasseurs d’approcher discrètement les troupeaux de narvals. Des harpons à propulseur et à tête basculante, ainsi que des systèmes de flotteurs et de freins perfectionnés pour une meilleure adaptation au contexte de la chasse au narval, donnent aux chasseurs l’opportunité de chasses fructueuses. Après une description ethnographique des chasseurs à la poursuite des narvals dans le fjord Inglefield, j’analyserai la stratégie de la chasse et la technique de lancer du harpon à propulseur depuis leurs kayaks. Je décrirai aussi la conception exceptionnellement sophistiquée de leurs armes et de leurs kayaks. Enfin, je discuterai de l’appropriation et de la redistribution du gibier capturé, ainsi que de l’évolution de la pratique de la chasse et de l’impact de nouvelles réglementations visant à protéger les narvals dans cette zone de reproduction.
Comparison of automatic airway analysis function of Invivo5 and Romexis software
Authors: Kamaruddin Noorshaida , Daud Firdaus , Yusof Asilah , Aziz Mohd Ezane , Rajion Zainul A. 
Published: January 2019

Background
Visualization and calculation of the airway dimensions are important because an increase of airway resistance may lead to life-threatening emergencies. The visualization and calculation of the airway are possible using radiography technique with their advance software. The aim of this study was to compare and to test the reliability of the measurement of the upper airway volume and minimum area using airway analysis function in two software.

Methods
The sample consisted of 11 cone-beam computed tomography (CBCT) scans data, evaluated using the Invivo5 (Anatomage) and Romexis (version 3.8.2.R, Planmeca) software which afford image reconstruction, and airway analysis. The measurements were done twice with one week gap between the two measurements. The measurement obtained was analyzed with t-tests and intraclass correlation coefficient (ICC), with confidence intervals (CI) was set at 95%.

Results
From the analysis, the mean reading of volume and minimum area is not significantly different between Invivo5 and Romexis. Excellent intrarater reliability values were found for the both measurement on both software, with ICC values ranging from 0.940 to 0.998.

Discussion
The results suggested that both software can be used in further studies to investigate upper airway, thereby contributing to the diagnosis of upper airway obstructions.
Silver Nanoparticles Supported on Chitosan as a Green and Robust Heterogeneous Catalyst for Direct Synthesis of Nitrogen Heterocyclic Compounds under Green Conditions
Authors: Hamzavi Seyedeh Fazileh Fazileh , Jamili Shahla , Yousefzadi Morteza , Moradi Ali Mashinchian , Biuki Narges Amrollahi 
Published: January 2019

The catalytic efficiency of silver nanoparticles supported on chitosan as a green, robust, and efficient nanocatalyst for the direct synthesis of biologically active compounds, such as: imidazole derivatives as well as pyrazine scaffolds through multi-component reactions strategy, have been demonstrated. In this work, imidazole derivatives were achieved via pseudo four-component reactions by utilization of benzaldehydes, benzils, anilines, and ammonium acetate under solvent-free conditions. Moreover, pyrazine scaffolds were synthesized through a three-component reaction of phenylenediamine derivatives, isocyanides and various ketones in water. The main advantages of this protocol are the reusability of the catalyst, operational simplicity, mild reaction conditions, and high-yielding.
Laparoscopic Cytoreduction After Neoadjuvant Chemotherapy in High-Grade Epithelial Ovarian Cancer
Authors: Rauh-Hain J. Alejandro , Melamed Alexander , Pareja René , May Taymaa , Sinno Abdulrahman , McNally Leah , Horowitz Neil S. , De Iaco Pierandrea , Michener Chad M. , Van Lonkhuijzen Luc , Iniesta Maria D. , Yuan Ying , Ramirez Pedro T. , Fagotti Anna 
Published: November 2024

ImportanceDespite the absence of high-quality evidence of its safety and effectiveness, minimally invasive surgery (MIS) is increasingly used to treat advanced epithelial ovarian cancer (EOC).ObjectiveTo assess the feasibility of conducting a full-scale randomized clinical trial (RCT) designed to compare the efficacy of MIS vs laparotomy in patients with advanced-stage EOC and a complete or partial response to neoadjuvant chemotherapy (NACT).Design, Setting, and ParticipantsThis lead-in pilot phase of LANCE (Laparoscopic Cytoreduction After Neoadjuvant Chemotherapy), an international, open-label, noninferiority RCT, opened to enrollment in September 2020 and enrolled the 100th eligible patient in February 2023. It was conducted at 11 academic cancer centers in North America and Europe. Participants were adults with stage IIIC or IV epithelial ovarian, fallopian, or primary peritoneal carcinoma who had normal cancer antigen 125 levels and at least a partial radiologic response after 3 to 4 cycles of NACT. Patients were randomly assigned to receive either interval cytoreductive surgery performed using MIS or laparotomy. Data analysis was based on the evaluable population.InterventionsThe MIS arm underwent laparoscopic or robotic surgery, vs laparotomy for the control arm. Resection of all visible tumor was attempted, and conversion from MIS to laparotomy was performed when necessary to attain complete resection.Main Outcomes and MeasuresTrial feasibility was defined by 3 primary end points: patient accrual rate of at least 5.6 patients per month by the last month of the lead-in pilot phase, conversion from MIS to laparotomy in less than 25% of patients, and a difference in complete gross resection rates of fewer than 20 percentage points between study arms.ResultsOne hundred women (median [IQR] age, 63 [39-82] years) were included, of whom 49 were randomly assigned to MIS and 51 to laparotomy; 95 were evaluable for surgical outcomes. Most patients (34 [67%] in the laparotomy arm, and 33 [67%] in the MIS arm) had stage IIIC cancer. The monthly accrual rate reached 5.9 patients per month in the final month of the study. Six of 48 evaluable patients (12.5%; 95% CI, 4.7%-25.2%) assigned to MIS underwent conversion to laparotomy. Surgeons achieved a complete gross resection rate in 42 of 48 evaluable patients (88%) assigned to MIS and in 39 of 47 patients (83%) assigned to laparotomy (difference, 4.5 [95% CI, −9.7 to 18.8] percentage points).Conclusions and RelevanceResults of this lead-in pilot study indicated the feasibility of the LANCE RCT to compare the oncological outcomes of MIS vs laparotomy.Trial RegistrationClinicalTrials.gov Identifier: NCT04575935
Capturing Fingerprint Expertise With Protocol Analysis
Authors: Corbett Brooklyn J. , Tangen Jason M. 
Published: November 2024

ABSTRACTIn this study, we used think‐aloud protocols to compare how 44 fingerprint examiners and 44 novices analysed prints. Through this qualitative approach, we discovered several notable differences. Experts focused on local ridge characteristics and minute details of each print, while novices concentrated more on global features. Additionally, experts demonstrated adaptability in dynamically planning their systematic approach and integrated specialised knowledge of causal factors affecting prints. In contrast, the novices relied more on general intuition. Furthermore, experts consistently displayed critical thinking and metacognition, carefully weighing the reliability of each identifying feature before making conclusions. However, there was variation in the precise evaluation approaches and conclusion thresholds among experts. Overall, these findings reveal the substantial complexity, adaptability and domain knowledge enhancing expert performance in fingerprint analysis. We discuss implications including balancing training of intuitive and analytical reasoning, implementing more detailed documentation, incorporating falsification practices and driving statistical advancements to strengthen evidence evaluation.
Band Structure and Spin‐State‐Induced Electronic Configuration Regulation for Efficient Sulfur Redox Reaction
Authors: Zhou Fei , Gong Zhiqi , Wang Renheng , Guo Mengran , Zeng Rong , Li Yun , Xiao Zhe , Qie Long , Liu Jianwen 
Published: November 2024

AbstractDeciphering the relationship between electron configuration and catalytic activity is crucial for designing electrocatalysts that improve the efficient conversion of lithium polysulfides (LiPSs). In this study, amorphous ZnAl2O4 (referred to as A‐ZnAl2O4) is designed with a high oxygen vacancy concentration. Experimental and theoretical analysis confirm that the Zn tetrahedral sites are sufficiently exposed, and the catalytic activity is significantly enhanced due to a narrow bandgap and a high spin state achieved through low coordination numbers and a disordered structure. Both the enhancement in electron transfer efficiency and reduction in reaction energy barriers accelerate the multi‐phase transformation of LiPSs, resulting in impressive electrochemical performance with a capacity retention rate of 93.9% after 800 cycles at a high current density of 4 C. And the pouch battery with high sulfur loading of 4.5 mg cm−2 and lean electrolyte at 8 µL mg−1 exhibits high discharge capacity and stable cycling. This research deciphers the amorphization on modulating electronic structures to achieve enhanced electrocatalytic activity, providing a general strategy for designing unique atomic‐scale band structures and spin states in multifunctional electrocatalysts.
Sustainable Smart Packaging from Protein Nanofibrils
Authors: Peydayesh Mohammad , Kovacevic Alan , Hoffmann Leah , Donat Felix , Wobill Ciatta , Baraldi Laura , Zhou Jiangtao , Müller Christoph R. , Mezzenga Raffaele 
Published: November 2024

AbstractSmart packaging technologies are revolutionizing the food industry by extending shelf life and enhancing quality monitoring through environmental responsiveness. Here, a novel smart packaging concept is presented, based on amyloid fibrils (AM) and red radish anthocyanins (RRA), to effectively monitor food spoilage by color change. A protein nanofibrils biofilm is developed from whey protein, which is functionalized with RRA to endow the resulting films with advanced monitoring capabilities. A comprehensive characterization, including pH responsiveness, water vapor permeability, thermal and mechanical testing, and colorimetric responses, demonstrates the superiority of AM/RRA films compared to control films based on whey monomer building blocks. The findings indicate that the AM/RRA films can effectively monitor, for example, shrimp freshness, showing visible changes within one day at room temperature and significant alterations in color after two days. Furthermore, these films exhibit high antibacterial and antioxidant activities, reinforcing their suitability for efficient food packaging. By integrating bio‐based materials from whey and natural anthocyanins, this research presents a biodegradable, sustainable, and cost‐effective smart packaging solution, contributing to eco‐friendly innovations in food preservation.