bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exotic complexes in one-dimensional Bose-Einstein condensates with spin-orbit coupling
Authors: Belobo D. Belobo , Meier T. 
Published: February 2018

AbstractBy means of the F-expansion method and intensive numerical simulations, the existence of three families of nonlinear matter waves including Jacobi elliptic functions, solitons, and triangular periodic functions, is demonstrated for spin-orbit coupled Bose-Einstein condensates with a linear potential. In addition, several complexes are obtained by taking two distinct solutions of each family or two distinct families. These solutions sustain different types of two-body interactions in the condensate that can be repulsive, attractive, or attractive and repulsive. Whereas the spin-orbit coupling destabilized these nonlinear matter waves, the linear potential leads to a stabilization. The numerical results are in excellent agreement with our analytical findings and it can be expected that the proposed robust solutions should be observable for experimentally relevant conditions.
High strength films from oriented, hydrogen-bonded “graphamid” 2D polymer molecular ensembles
Authors: Sandoz-Rosado Emil , Beaudet Todd D. , Andzelm Jan W. , Wetzel Eric D. 
Published: February 2018

AbstractThe linear polymer poly(p-phenylene terephthalamide), better known by its tradename Kevlar, is an icon of modern materials science due to its remarkable strength, stiffness, and environmental resistance. Here, we propose a new two-dimensional (2D) polymer, “graphamid”, that closely resembles Kevlar in chemical structure, but is mechanically advantaged by virtue of its 2D structure. Using atomistic calculations, we show that graphamid comprises covalently-bonded sheets bridged by a high population of strong intermolecular hydrogen bonds. Molecular and micromechanical calculations predict that these strong intermolecular interactions allow stiff, high strength (6–8 GPa), and tough films from ensembles of finite graphamid molecules. In contrast, traditional 2D materials like graphene have weak intermolecular interactions, leading to ensembles of low strength (0.1–0.5 GPa) and brittle fracture behavior. These results suggest that hydrogen-bonded 2D polymers like graphamid would be transformative in enabling scalable, lightweight, high performance polymer films of unprecedented mechanical performance.
Fast, sensitive method for trisaccharide biomarker detection in mucopolysaccharidosis type 1
Authors: Makino Elina , Klodnitsky Helen , Leonard John , Lillie James , Lund Troy C. , Marshall John , Nietupski Jennifer , Orchard Paul J. , Miller Weston P. , Phaneuf Clifford , Tietz Drew , Varban Mariet L. , Donovan Marissa , Belenki Alexey 
Published: February 2018

AbstractCertain recessively inherited diseases result from an enzyme deficiency within lysosomes. In mucopolysaccharidoses (MPS), a defect in glycosaminoglycan (GAG) degradation leads to GAG accumulation followed by progressive organ and multiple system dysfunctions. Current methods of GAG analysis used to diagnose and monitor the diseases lack sensitivity and throughput. Here we report a LC-MS method with accurate metabolite mass analysis for identifying and quantifying biomarkers for MPS type I without the need for extensive sample preparation. The method revealed 225 LC-MS features that were >1000-fold enriched in urine, plasma and tissue extracts from untreated MPS I mice compared to MPS I mice treated with iduronidase to correct the disorder. Levels of several trisaccharides were elevated >10000-fold. To validate the clinical relevance of our method, we confirmed the presence of these biomarkers in urine, plasma and cerebrospinal fluid from MPS I patients and assessed changes in their levels after treatment.
Gender bias in clinicians’ pathologization of atypical sexuality: a randomized controlled trial with mental health professionals
Authors: Fuss Johannes , Briken Peer , Klein Verena 
Published: February 2018

AbstractThe psychiatric classification of “normal” versus disordered sexual behavior has been a subject of some dispute. Although atypical sexual interests have been viewed traditionally as typically male, epidemiological data indicate its presence in both genders. We examined how gender and sexual orientation influence whether or not atypical sexual behavior is classified as a mental disorder. Mental health professionals (N = 546) were presented with five case vignettes where subjects exhibit paraphilic behaviors; one case with psychotic symptoms served as the control condition. For each vignette we randomly changed the described subject’s gender (male/female), sexual orientation (homosexual/heterosexual), and presented diagnostic criteria (fulfilled/ambiguous). Female subjects were significantly less pathologized and overall less stigmatized in terms of exhibitionistic, frotteuristic, sexual sadistic and pedophilic behavior. On the other hand, female sexual behavior that fulfilled diagnostic criteria for masochistic disorder was more pathologized. Our results demonstrate that nosologically irrelevant factors, which may be related to different sexual norms for men and women, affect clinicians’ decisions regarding atypical sexuality.
An International Survey of Assessment Practices for Short-Term and Working Memory Deficits in Aphasia
Authors: Salis Christos , Murray Laura , Bakas Katrina 
Published: February 2018

Purpose
Recent research has highlighted the clinical relevance of understanding the nature of short-term memory (STM) and working memory (WM) deficits in persons with aphasia and the way these deficits affect linguistic processing and functional communication in activities of daily living. The psychometric properties of tests commonly used to identify STM/WM problems in individuals with aphasia, however, have been questioned. No previous study has sought to investigate assessment practices and attitudes by speech-language pathologists involved in aphasia management. Accordingly, the aims of this study were (a) to investigate both attitudes toward STM/WM assessment in individuals with aphasia, as well as the types and frequency of STM/WM tests used with individuals with aphasia, and (b) to explore factors (e.g., educational background) that may influence STM/WM assessment practices.

Method
Respondents recruited via professional and aphasia support organizations completed an online survey. The survey elicited information about the respondents' demographic and clinical backgrounds and STM/WM assessment clinical practices and views, including frequency and preferred use of specific STM/WM tests.

Results
The majority of respondents reported regular use of STM/WM tests as part of aphasia management. Positive attitudes toward STM/WM assessments were also reported. The most popular rankings of tests were the Cognitive Linguistic Quick Test (Helm-Estabrooks, 2001), the Comprehensive Aphasia Test (Swinburn, Porter, & Howard, 2005), and the Token Test (McNeil & Prescott, 1978). Results suggested limited knowledge about measures that assess self-perceptions of functional memory abilities. Regression analyses showed that the frequency of reported STM/WM test use was similar between clinicians and dual-role researchers/clinicians, but their attitudes toward the value of STM/WM differed. U.S. and UK respondents reported similar assessment practices.

Conclusions
It is reassuring that STM/WM is taken into consideration by clinicians when providing aphasia management. Two of the most popular tests, however, have poor psychometric properties, and caution should be exercised in clinical decision making. The different value placed on STM/WM testing by clinicians and researchers/clinicians has implications for continuing professional development.
Solar type III radio burst time characteristics at LOFAR frequencies and the implications for electron beam transport
Authors: Reid Hamish A. S. , Kontar Eduard P. 
Published: February 2018

Context. Solar type III radio bursts contain a wealth of information about the dynamics of electron beams in the solar corona and the inner heliosphere; this information is currently unobtainable through other means. However, the motion of different regions of an electron beam (front, middle, and back) have never been systematically analysed before.
Aims. We characterise the type III burst frequency-time evolution using the enhanced resolution of LOFAR (LOw Frequency ARray) in the frequency range 30–70 MHz and use this to probe electron beam dynamics.
Methods. The rise, peak, and decay times with a ~0.2 MHz spectral resolution were defined for a collection of 31 type III bursts. The frequency evolution was used to ascertain the apparent velocities of the front, middle, and back of the type III sources, and the trends were interpreted using theoretical and numerical treatments.
Results. The type III time profile was better approximated by an asymmetric Gaussian profile and not an exponential, as was used previously. Rise and decay times increased with decreasing frequency and showed a strong correlation. Durations were shorter than previously observed. Drift rates from the rise times were faster than from the decay times, corresponding to inferred mean electron beam speeds for the front, middle, and back of 0.2, 0.17, 0.15 c, respectively. Faster beam speeds correlate with shorter type III durations. We also find that the type III frequency bandwidth decreases as frequency decreases.
Conclusions. The different speeds naturally explain the elongation of an electron beam in space as it propagates through the heliosphere. The expansion rate is proportional to the mean speed of the exciter; faster beams expand faster. Beam speeds are attributed to varying ensembles of electron energies at the front, middle, and back of the beam.
Geriatrische Dens axis Fraktur – Pro Operation!
Authors: Schnake Klaus 
Published: February 2018

ZusammenfassungGeriatrische Typ 2 Dens axis Frakturen können erfolgreich operativ behandelt werden. Im Vergleich zur konservativen Therapie ist die knöcherne Heilungsrate bei operativer Therapie signifikant höher bei gleicher oder geringerer Mortalität. Weitere Vorteile für die chirurgische Therapie zeigen sich im klinischen Ergebnis und der Kosteneffizienz.
Luxationsfrakturen der unteren HWS – dorsal beginnen!
Authors: Stoffel Michael 
Published: February 2018

AbstractLuxationsfrakturen der unteren HWS – also ab Hw3 abwärts – sind komplexe und meist hoch instabile Verletzungen, die einer operativen Therapie bedürfen. In diesem Pro/Kontra-Beitrag werden diese Verletzungen zunächst in die Systematik der AO-Spine Klassifikation eingeordnet, die adäquate Diagnostik erläutert und die Behandlungsziele definiert. Nach Vorstellung der grundsätzlichen Therapieoptionen werden die Bedingungen dargelegt, die für ein primär dorsales Vorgehen sprechen: (1) eine dorsal des Myelons gelegene traumatische Raumforderung oder die Notwendigkeit zur mehrsegmentalen Dekompression, (2) eine traumatische Foramenstenose, (3) eine ankylosierende Grunderkrankung oder (4) eine verminderte Knochendichte.
RETRACTED: Research on Data Mining of the Internet of Things Based on Cloud Computing Platform
Authors: Zhang Wenqing 
Published: February 2018

Abstract
Based on the development of society and the progress of information technology, China’s information industry has made great progress and has gradually become an important pillar of national economic development. In this context, the gradual integration of information technology had promoted the construction of the Internet of Things system, so as to promote the human life developed in the direction of modernization intelligently. At present, in the process of forming the development of the Internet of Things the first need to fully tap the data, which thus provide users with better service, for the development of large-scale development of the Internet. This paper analyzes the meaning of Internet of things, and discusses the characteristics of Internet of things and data mining, hoping to promote the improvement on the Internet of Things system in China, and thus promote the realization of higher efficiency.
RETRACTED: Research on Technology Innovation Management in Big Data Environment
Authors: Ma Yanhong 
Published: February 2018

Abstract
With the continuous development and progress of the information age, the demand for information is getting larger. The processing and analysis of information data is also moving toward the direction of scale. The increasing number of information data makes people have higher demands on processing technology. The explosive growth of information data onto the current society have prompted the advent of the era of big data. At present, people have more value and significance in producing and processing various kinds of information and data in their lives. How to use big data technology to process and analyze information data quickly to improve the level of big data management is an important stage to promote the current development of information and data processing technology in our country. To some extent, innovative research on the management methods of information technology in the era of big data can enhance our overall strength and make China be an invincible position in the development of the big data era.
nVenn: generalized, quasi-proportional Venn and Euler diagrams
Authors: Pérez-Silva José G , Araujo-Voces Miguel , Quesada Víctor 
Published: February 2018

Abstract

Motivation
Venn and Euler diagrams are extensively used for the visualization of relationships between experiments and datasets. However, representing more than three datasets while keeping the proportions of each region is still not feasible with existing tools.

Results
We present an algorithm to render all the regions of a generalized n-dimensional Venn diagram, while keeping the area of each region approximately proportional to the number of elements included. In addition, missing regions in Euler diagrams lead to simplified representations. The algorithm generates an n-dimensional Venn diagram and inserts circles of given areas in each region. Then, the diagram is rearranged with a dynamic, self-correcting simulation in which each set border is contracted until it contacts the circles inside. This algorithm is implemented in a C++ tool (nVenn) with or without a web interface. The web interface also provides the ability to analyze the regions of the diagram.

Availability and implementation
The source code and pre-compiled binaries of nVenn are available at https://github.com/vqf/nVenn. A web interface for up to six sets can be accessed at http://degradome.uniovi.es/cgi-bin/nVenn/nvenn.cgi.

Supplementary information
Supplementary data are available at Bioinformatics online.
Idiopathic pulmonary fibrosis
Authors: Vega-Olivo Michelle , Criner Gerard J. 
Published: February 2018

Abstract:
Idiopathic pulmonary fibrosis (IPF) is a rare disease characterized by decline in lung function, dyspnea, and cough. The clinical course of IPF is variable and unpredictable. Early referral to specialists is key to ensure timely and accurate diagnosis. Two antifibrotic drugs (nintedanib and pirfenidone) have been approved for the treatment of IPF.
A Comparison of Approaches for Mastery Learning Standard Setting
Authors: Barsuk Jeffrey H. , Cohen Elaine R. , Wayne Diane B. , McGaghie William C. , Yudkowsky Rachel 
Published: February 2018

Purpose
Defensible minimum passing standards (MPSs) must be used to evaluate learner performance outcomes in health professions education. In this study, the authors compared the results of traditional Angoff and Hofstee standard-setting exercises with the Mastery Angoff and Patient-Safety approaches for central venous catheter (CVC) insertion skills examinations. The authors also evaluated how these standards affected the historical performance of residents who participated in a simulation-based mastery learning (SBML) curriculum for CVC insertion skills.

Method
In April and May 2015, 12 physicians with expertise in CVC insertion set MPSs for previously published internal jugular (IJ) and subclavian (SC) CVC insertion checklists using Angoff, Hofstee, Mastery Angoff, and Patient-Safety approaches. The resulting MPSs were compared using historical performance of internal medicine and emergency medicine residents who participated in CVC insertion SBML.

Results
The MPSs were set as follows: Angoff: IJ 91% checklist items correct, SC 90%. Hofstee: IJ 88%, SC 90%. Mastery Angoff: IJ 98%, SC 98%. Patient-Safety: IJ 98%, SC 98%. Based on the historical performance of 143 residents assessed on IJ and SC insertion, applying the 98% MPS would result in additional practice and retesting of 55/123 residents (45%) who had previously passed the IJ examination and 36/130 residents (28%) who had passed the SC examination using the Angoff and Hofstee MPSs.

Conclusions
The Mastery Angoff and Patient-Safety standard-setting approaches resulted in higher CVC insertion SBML MPSs compared with traditional standard-setting methods. Further study should assess the impact of these more rigorous standards on patient outcomes.
Psychological Factors and the Development of Chronic Whiplash–associated Disorder(s)
Authors: Campbell Letitia , Smith Ashley , McGregor Leanne , Sterling Michele 
Published: February 2018

Objectives:
To assess which psychological factors are important in the development of chronic whiplash symptoms.

Methods:
Searches were conducted across PubMed, CINAHL, Scopus, and PsychINFO up until March 2017. Studies were included if they investigated psychological prognostic factors in association with recovery from a whiplash injury. Studies also had to be prospective, cohort, follow-up or observational studies, have a 6 month follow-up and published in English. Quality assessments were conducted by 2 independent reviewers. Thirty-one articles were included investigating 34 psychological factors.

Results:
Poor expectations of recovery, posttraumatic stress symptoms and passive coping emerged as the most consistent prognostic factors of chronic neck pain and/or disability after a whiplash injury. Anxiety, travel anxiety, depression, personality, precollision distress, general psychological distress, and avoidance behavior were not associated with chronic whiplash problems.
The Effects of Leukocyte Filtration on Cell Salvaged Autologous Blood Transfusion on Lung Function and Lung Inflammatory and Oxidative Stress Reactions in Elderly Patients Undergoing Lumbar Spinal Surgery
Authors: Xu Lili , Shen Jianjun , Sun Jianliang , McQuillan Patrick M. , Hu Zhiyong 
Published: February 2018

Background:
This study was designed to investigate the effects of leukocyte filtration of autologous salvaged blood on lung function, lung inflammatory reaction, and oxidative stress reaction in elderly patients undergoing lumbar spinal surgery.

Materials and Methods:
Sixty elderly patients undergoing lumbar spinal surgery were randomly divided into 2 groups: Leukocyte Filter group and Control group. Serum levels of inflammatory markers including white blood cell and polymorphonuclear count, neutrophil elastase, serum surfactant protein A, methane dicarboxylic aldehyde, superoxide dismutase, interleukin (IL)-6, IL-8, tumor necrosis factor-α, and respiratory function markers including dynamic respiratory system compliance, oxygenation index, and respiratory index were measured immediately before induction of anesthesia (T0), immediately before blood transfusion (T1), and 1 (T2), 6 (T3), and 12 hours (T4) after end of blood transfusion.

Results:
The Leukocyte Filter group had higher dynamic respiratory system compliance at T2, oxygenation index at T2 and T3, respiratory index and superoxide dismutase at T2, T3, and T4 than those in the Control group (P<0.05). The Leukocyte Filter group had lower white blood cell, polymorphonuclear count, neutrophil elastase, serum surfactant protein A, methane dicarboxylic aldehyde, IL-6, IL-8, and tumor necrosis factor-α at T2, T3, and T4 than those in the Control group (P<0.05). There were no significant differences in adverse reactions related specifically to blood transfusion or postoperative respiratory complications within 72 hours.

Conclusions:
Salvaged autologous blood leukocyte filtration can improve ventilation, promote gas exchange and oxygenation, and inhibit lung inflammatory and oxidative stress reactions in elderly patients undergoing lumbar spinal surgery.
The Five-Year Clinical and Angiographic Follow-Up Outcomes of Intracoronary Transfusion of Circulation-Derived CD34+ Cells for Patients With End-Stage Diffuse Coronary Artery Disease Unsuitable for Coronary Intervention—Phase I Clinical Trial
Authors: Sung Pei-Hsun , Lee Fan-Yen , Tong Meng-Shen , Chiang John Y. , Pei Sung-Nan , Ma Ming-Chun , Li Yi-Chen , Chen Yung-Lung , Wu Chiung-Jen , Sheu Jiunn-Jye , Lee Mel S. , Yip Hon-Kan 
Published: February 2018

Objectives:
This study investigated the clinical and angiographic long-term outcomes of intracoronary transfusion of circulation-derived CD34+ cells for patients with end-stage diffuse coronary artery disease unsuitable for coronary intervention.

Design and Setting:
A single-center prospective randomized double-blinded phase I clinical trial. Thirty-eight patients undergoing CD34+ cell therapy were allocated into groups 1 (1.0 × 107 cells/each vessel; n = 18) and 2 (3.0 × 107 cells/each vessel; n = 20).

Patients:
Those with end-stage diffuse coronary artery disease were unsuitable for percutaneous and surgical coronary revascularization.

Interventions:
Intracoronary delivery of circulation-derived CD34+ cells.

Measurements and Main Results:
We prospectively evaluated long-term clinical and echocardiographic/angiographic outcomes between survivors and nonsurvivors. By the end of 5-year follow-up, the survival rate and major adverse cardio/cerebrovascular event were 78.9% (30/38) and 36.8% (14/38), respectively. During follow-up period, 31.6% patients (12/38) received coronary stenting for reason of sufficient target vessel size grown-up after the treatment. Endothelial function was significantly reduced in the nonsurvivors than the survivors (p = 0.039). Wimasis image analysis of angiographic findings showed that the angiogenesis was significantly and progressively increased from baseline to 1 and 5 years (all p < 0.001). The 3D echocardiography showed left ventricular ejection fraction increased from baseline to 1 year and then remained stable up to 5 years, whereas left ventricular chamber diameter exhibited an opposite pattern to left ventricular ejection fraction among the survivors. The clinical scores for angina and heart failure were significantly progressively reduced from baseline to 1 and 5 years (all p < 0.001).

Conclusions:
CD34+ cell therapy for end-stage diffuse coronary artery disease patients might contribute to persistently long-term effects on improvement of left ventricular function, angina/heart failure, and amelioration of left ventricular remodeling.
Novel Myelin Protein Zero Mutation in 3 Generations of Vermonters With Demyelinating Charcot–Marie–Tooth Disease
Authors: Lorance David K. , Mandigo Kelly A. , Hehir Michael K. 
Published: February 2018

Abstract

Objectives:
We report the clinical phenotype in 3 consecutive generations with demyelinating Charcot–Marie–Tooth disease that possess a novel sequence variant of myelin protein zero (MPZ).

Methods:
Family members from 3 consecutive generations were interviewed, examined, and studied with electrodiagnostic testing. Commercially available next-generation sequencing was performed for the proband. Single-gene analysis was performed for the remaining family members.

Results:
All patients demonstrated symmetric distal weakness; symmetric distal sensory loss; and diminished deep tendon reflexes. Electrodiagnostic testing was consistent with primary distal demyelination with secondary axon loss. Genetic testing identified a novel base-pair substitution of MPZ (c.314C>T), resulting in a missense variant (p.Pro105Leu).

Conclusions:
The novel MPZ base-pair substitution in this family is associated with inherited distal demyelinating neuropathy and should be reclassified as pathogenic for Charcot–Marie–Tooth.