bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prenatal detection of isolated bilateral hyperechogenic kidneys: Etiologies and outcomes
Authors: Shuster Shirley , Keunen Johannes , Shannon Patrick , Watkins Nicholas , Chong Karen , Chitayat David 
Published: January 2019

AbstractObjectivesTo delineate the etiology and outcome of prenatally diagnosed isolated bilateral hyperechogenic kidneys (IBHK).Study DesignPregnancies with IBHK on prenatal ultrasound identified and followed by us between January 1, 2000 and January 1, 2015 were evaluated regarding the etiology and outcome by evaluation of family history, targeted AR‐PKD and AD‐PKD DNA analysis, and microarray analysis, according to renal size and amniotic fluid volume.ResultsOf the 52 identified cases, there were 34 cases with enlarged kidneys, 16 with normal size kidneys, and two with small kidneys. There were seven cases with AD‐PKD, six inherited, and one with de novo causative variants in the PKD1 gene. Fifteen had AR‐PKD, and microarray analysis showed two inherited findings: one with 17q12 deletion including the HNF1B/TCF2 gene inherited from asymptomatic mother and a duplication at 3p26.1 inherited from a healthy father. Of the remaining four cases, three cases had bilateral multicystic dysplastic kidneys, and one had unilateral renal agenesis.ConclusionMicroarray analysis and mutation analysis for PKD1 and PKHD1 have an important contribution to the diagnostic investigation of IBHK and to the management of affected and future pregnancies. Poor outcome was associated with large hyperechoic kidneys with oligohydramnios.
The Proteomic Profile of Keratinocytes and Lymphocytes in Psoriatic Patients
Authors: Gęgotek Agnieszka , Domingues Pedro , Wroński Adam , Ambrożewicz Ewa , Skrzydlewska Elżbieta 
Published: January 2019

PurposePsoriatic skin lesions are associated with chronic inflammation related to immune cell activity. Therefore, the aim of this study is to compare changes in the proteome of psoriatic keratinocytes and lymphocytes.Experimental DesignA proteomics approach is used to analyze the expression of proteins in keratinocytes and lymphocytes from psoriatic patients and healthy controls.ResultsAs a result 2119 proteins for keratinocytes and 1235 proteins for lymphocytes are identified. Psoriatic keratinocytes has 68 downregulated and 7 upregulated proteins and psoriatic lymphocytes has 106 downregulated and 67 upregulated proteins compared to healthy individuals. The list of downregulated proteins includes proteins involved in antioxidant homeostasis and, transcription regulation; upregulated proteins are involved in glycolytic processes and translation. These changes are accompanied by an increased level of 4‐Hydroxynonenal‐protein adducts; control cells are characterized by 4‐Hydroxynonenal‐Lysine adducts formed with structural and binding proteins, while in psoriatic cells 4‐Hydroxynonenal‐Lysine, 4‐Hydroxynonenal‐Histidine, and 4‐Hydroxynonenal‐Cysteine adducts with various molecular function proteins occur.Conclusions and Clinical RelevanceThis study highlights the changes in psoriatic keratinocytes and lymphocytes that can be directly involved in the development of psoriasis. In both cell types the most significant changes are associated with upregulation of phosphoglycerate mutase 1 and downregulation of thioredoxin reductase.
Proteomic Profiling of Acute Promyelocytic Leukemia Identifies Two Protein Signatures Associated with Relapse
Authors: Hoff Fieke W. , Hu Chenyue W. , Qutub Amina A. , Qiu Yihua , Hornbaker Marisa J. , Bueso‐Ramos Carlos , Abbas Hussein A. , Post Sean M. , de Bont Eveline S. J. M. , Kornblau Steven M. 
Published: January 2019

PurposeAcute promyelocytic leukemia (APL) is the most prognostically favorable subtype of Acute myeloid leukemia (AML). Defining the features that allow identification of APL patients likely to relapse after therapy remains challenging.Experimental DesignProteomic profiling is performed on 20 newly diagnosed APL, 205 non‐APL AML, and 10 normal CD34+ samples using Reverse Phase Protein Arrays probed with 230 antibodies.ResultsComparison between APL and non‐APL AML samples identifies 8.3% of the proteins to be differentially expressed. Proteins higher expressed in APL are involved in the pro‐apoptotic pathways or are linked to higher proliferation. The “MetaGalaxy” approach that considers proteins in relation to other assayed proteins stratifies the APL patients into two protein signatures. All of the relapse patients (n = 4/4) are in protein signature 2 (S2). Comparison of proteins between the signatures shows significant differences in relative expression for 38 proteins. Protein expression summary plots suggest less translational activity in combination with a less proliferative character for S2 compared to signature 1.Conclusions and Clinical RelevanceThis study provides a potential proteomic‐based classification of APL patients that may be useful for risk stratification and therapeutic guidance. Validation in a larger independent cohort is required.
Development and validation of PART (Pharmacotherapy Assessment in Renal Transplant Patients) criteria to assess drug‐related problems in an outpatient renal transplant population: A cross‐sectional study
Authors: El Raichani Layal , Du Qian , Mathieu Alexandre , Almassy Sabrina , Lalonde Lyne , Berbiche Djamal , Gélinas‐Lemay Elisabeth , Boudreau Nathalie , Cardinal Héloïse 
Published: January 2019

AbstractKidney transplant recipients are at risk of pharmacological interactions and adverse drug reactions. Community pharmacists are uniquely poised to detect and intervene in cases of drug‐related problems. The aims of this study were to develop and validate a list of explicit criteria to be used by community pharmacists to assess drug‐related problems in kidney transplant patients, and to assess their frequency and their determinants. First, we used a modified RAND method where a panel of experts established the PART (Pharmacotherapy Assessment in Renal Transplant Patient) criteria. Then, we performed a cross‐sectional study in which we applied the PART criteria to 97 prevalent kidney transplant recipients followed at a single university‐affiliated center. The final list of PART criteria included 70 drug‐related problems and was reliable (kappa: 0.88). An average of 1.2 drug‐related problems per patient was detected when the PART criteria were applied, with 68% of patients having at least 1 problem. This figure was 1.4 per patient using the expert judgment of renal transplant pharmacists who had no access to the PART list. The total number of medications taken was the only factor associated with the number of drug‐related problems (β: 0.27 for an increase of five medications, 95% CI 0.005, 0.547). The PART criteria provide a novel tool for community pharmacists to systematically detect drug‐related problems in kidney transplant recipients.
Impact of curcumin on energy metabolism in HIV infection: A case study
Authors: da Silva Tatiane Andreza Lima , Medeiros Radamés Maciel Vítor , de Medeiros Danielle Coutinho , Medeiros Rafaela Catherine S. C. , de Medeiros Jason Azevedo , de Medeiros Gidyenne Christine Bandeira Silva , de Andrade Ricardo Dias , Lais Lucia Leite , Silva Dantas Paulo Moreira 
Published: January 2019

Prolonged use of antiretroviral therapy (ART) has been associated with dyslipidemia and impaired energy substrate oxidation (SOxi). Curcumin is a natural bioactive compound, which interacts with molecular targets and holds important metabolic properties. The aim of this study was to evaluate the effect of curcumin supplementation on energetic metabolism of an adult female with HIV/AIDS and under ART. The intervention was performed with 500 mg/day of curcumin for 27 days. Glycemic and lipid profile and SOxi at rest were evaluated before and after intervention. After intervention, improvement of lipid profile and insulin sensibility was observed. Moreover, there was a positive modulation of SOxi at rest. Oral curcumin supplementation can positively modulate the energy metabolism of people living with HIV/AIDS using the ART. However, clinical studies are required in order to confirm our findings in a representative sample.
Share control of surgery robot master manipulator guiding tool along the standard path
Authors: Fracczak Lukasz , Szaniewski Mateusz , Podsedkowski Leszek 
Published: January 2019

AbstractRecently, minimally invasive surgery (MIS) robotics enters the phase of autonomous operation. However, because of the high variability of the environment, conducting a fully autonomous surgery is still extremely difficult. This paper presents a share control system, the objective of which is to suggest the optimum path of tool guidance through the use of force on the master manipulator (hereinafter as master), meaning the surgeon's hand. Owing to this type of control, the surgeon has full control over the position of the tool the entire time and is supported by the system to better and faster guide the tool during surgery. The force should be felt by the surgeon but, simultaneously, must not hinder or impact the surgical process. Furthermore, the share control system presented in the paper can be turned on or off at any moment during surgery.
Yolk–Shell Fe/Fe4N@Pd/C Magnetic Nanocomposite as an Efficient Recyclable ORR Electrocatalyst and SERS Substrate
Authors: Jiao Wenling , Chen Chen , You Wenbin , Zhang Jie , Liu Jiwei , Che Renchao 
Published: January 2019

AbstractA yolk–shell Fe/Fe4N@Pd/C (FFPC) nanocomposite is synthesized successfully by two facile steps: interfacial polymerization and annealing treatment. The concentration of Pd2+ is the key factor for the density of Pd nanoparticles (Pd NPs) embedded in the carbon shells, which plays a role in the oxygen reduction reaction (ORR) and surface‐enhanced Raman scattering (SERS) properties. The ORR and SERS performances of FFPC nanocomposites under different concentrations of PdCl2 are investigated. The optimal ORR performance exhibits that onset potential and tafel slope can reach 0.937 V (vs reversible hydrogen electrode (RHE)) and 74 mV dec−1, respectively, which is attributed to the synergistic effects of good electrical conductivity, large electrochemically active areas, and strong interfacial charge polarization. Off‐axis electron holography reveals that interfacial charge polarization could facilitate the ORR of Pd NPs and defective carbon simultaneously and the shell with low density of Pd NPs is easier to form strong interfacial charge polarization. Moreover, FFPC‐3 with maximum EF of 2.3 × 105 results from more hot‐spots, local positive charge centers to attract rhodamine 6G molecules, and magnetic cores. This work not only offers a recyclable multifunctional nanocomposite with excellent performance, but also has instructional implications for interfacial engineering for electrocatalysts design.
Framing the Study
Authors: Paus-Hasebrink Ingrid , Kulterer Jasmin , Sinner Philip 
Published: January 2019

AbstractThe introductory chapter of this book is in two parts. Part one illustrates how our concept pursues both academic and social goals. We outline its foundation in the Longitudinal Study on the Role of Media within Socialisation of Socially Disadvantaged Adolescents in terms of “dedicated social research”. It deals with the situation of socially disadvantaged families and adolescents against the backdrop of widening of inequality within society and an increasing participation gap. As nearly all parts of our everyday lives are strongly connected with media, we discuss all the above developments in relation to the meta-process of mediatization. Part two gives an overview of the book, with short summaries of the following eight chapters on theory, methodology, and results, as well as a concluding discussion.
On the Dissolution Process of Manganese and Iron in Molten Aluminum
Authors: Razaz Ghadir , Carlberg Torbjörn 
Published: January 2019

Abstract
The dissolution of Mn and Fe in liquid Al presents a challenge due to their high melting points and low diffusivity. A literature review reveals that the existing knowledge of the processes involved in the dissolution of both Fe and Mn in liquid Al is rather ambiguous. Thus, this work aimed to obtain more detailed insights into the dissolution behavior of Mn and Fe in various Al melts. The results of the Mn dissolution tests showed that three intermediate phases were involved in the dissolution process, all of which exhibited a smooth interface between Mn and the liquid. These three phases were identified as the γ2, Al11Mn4, and µ phases which grow slowly, penetrating the Mn particles. The results of the Fe dissolution tests showed that in pure Al, the Al5Fe2 phase dominates the dissolution process and penetrates the Fe particles. The addition of Ti into the molten Al alters the intermetallic compound formation by replacing Al5Fe2 by Al2Fe. The addition of Si significantly inhibited the Fe dissolution kinetics. A theoretical approach based on Ficks’ law was used to explain the experimentally obtained Mn and Fe dissolution rates. It showed that the surface area and shape of the additives significantly affected the dissolution processes.
Pride as a state and as a trait: Polish adaptation of the authentic and hubristic pride scales
Authors: Ślaski Sławomir , Rogoza Radosław , Strus Włodzimierz 
Published: January 2019

AbstractThe main purpose of the study of the presented article is to prepare the Polish version of the Authentic and Hubristic Pride Scales and to verify its psychometric properties: reliability, and factorial and external validity. Within the study, 210 participants aged between 20 and 56 were administered the following tests: Authentic and Hubristic Pride Scales, Rosenberg Self-Esteem Scale and Moral Feelings Scale. The Polish adaptation of the Authentic and Hubristic Pride Scales was demonstrated to be reliable in its measurement of authentic and hubristic pride. Moreover, factor analyses carried out under different methodological approaches confirmed that the validity of the two-dimensional model of pride and correlations with other psychological variables further support this distinction. The results indicate the validity of the Authentic and Hubristic Pride Scales for studying the two dimensions of pride in the Polish population.
Understanding (non)leadership phenomena in collaborative interorganizational networks and advancing shared leadership theory: an interpretive grounded theory study
Authors: Endres Sigrid , Weibler Jürgen 
Published: January 2019

AbstractDespite the increasing significance of collaborative interorganizational networks, understanding of leadership phenomena in these contexts is still scarce. How, and in what form will leadership emerge in such (a priori) non-hierarchical contexts with peerlike work settings, if at all? Through an interpretive grounded theory study conducted in collaborative interorganizational networks, we found that the networks either remained at the stage of leaderless cooperation (leadership void) or developed shared leadership. We then sought to understand the underlying mechanism of collaboration that might explain the different (non)leadership phenomena. Our study’s main result is the empirically grounded identification of two distinct forms of network participation with specific network identities as its core, which are related to the distinct leadership-related phenomena in our networks. (1)Task-based network identity, which includes an individualistic network identity, a single achievement motivation, and a largely instrumentalist orientation towards network participation, is related to aleadership void(non-leadership emergence, i.e. a form of leaderless cooperation). (2)Joint-motivational network identity, which includes a collectivistic network identity, joint network motivation, and a largely value-laden attitude towards network participation, is related toshared leadership. Our findings shed new light on collaboration and leadership phenomena in interorganizational networks, concurrently providing progress on conceptualizing shared leadership, in particular by introducing joint-motivational network identity as a new concept related to shared leadership development. We discuss implications for the management of collaborative interorganizational networks and advance theory on plural forms of leadership such as collective or shared leadership.
Convergence rates for estimators of geodesic distances and Frèchet expectations
Authors: Aaron Catherine , Bodart Olivier 
Published: January 2019

Abstract
Consider a sample 𝒳n={X1,…,Xn} of independent and identically distributed variables drawn with a probability distribution ℙX supported on a compact set M⊂ℝd. In this paper we mainly deal with the study of a natural estimator for the geodesic distance on M. Under rather general geometric assumptions on M, we prove a general convergence result. Assuming M to be a compact manifold of known dimension d′≤d, and under regularity assumptions on ℙX, we give an explicit convergence rate. In the case when M has no boundary, knowledge of the dimension d′ is not needed to obtain this convergence rate. The second part of the work consists in building an estimator for the Fréchet expectations on M, and proving its convergence under regularity conditions, applying the previous results.
Uniform decomposition of probability measures: quantization, clustering and rate of convergence
Authors: Chevallier Julien 
Published: January 2019

AbstractThe study of finite approximations of probability measures has a long history. In Xu and Berger (2017), the authors focused on constrained finite approximations and, in particular, uniform ones in dimensiond=1. In the present paper we give an elementary construction of a uniform decomposition of probability measures in dimensiond≥1. We then use this decomposition to obtain upper bounds on the rate of convergence of the optimal uniform approximation error. These bounds appear to be the generalization of the ones obtained by Xu and Berger (2017) and to be sharp for generic probability measures.
Partisan gerrymandering with geographically compact districts
Authors: Alexeev Boris , Mixon Dustin G. 
Published: January 2019

Abstract
Bizarrely shaped voting districts are frequently lambasted as likely instances of gerrymandering. In order to systematically identify such instances, researchers have devised several tests for so-called geographic compactness (i.e. shape niceness). We demonstrate that under certain conditions, a party can gerrymander a competitive state into geographically compact districts to win an average of over 70% of the districts. Our results suggest that geometric features alone may fail to adequately combat partisan gerrymandering.
The degree-wise effect of a second step for a random walk on a graph
Authors: Berenhaut Kenneth S. , Jiang Hongyi , McNab Katelyn M. , Krizay Elizabeth J. 
Published: January 2019

AbstractIn this paper we consider the degree-wise effect of a second step for a random walk on a graph. We prove that under the configuration model, for any fixed degree sequence the probability of exceeding a given degree threshold is smaller after two steps than after one. This builds on recent work of Krameret al.(2016) regarding the friendship paradox under random walks.
On optimal periodic dividend and capital injection strategies for spectrally negative Lévy models
Authors: Noba Kei , Pérez José-Luis , Yamazaki Kazutoshi , Yano Kouji 
Published: January 2019

Abstract
De Finetti’s optimal dividend problem has recently been extended to the case when dividend payments can be made only at Poisson arrival times. In this paper we consider the version with bail-outs where the surplus must be nonnegative uniformly in time. For a general spectrally negative Lévy model, we show the optimality of a Parisian-classical reflection strategy that pays the excess above a given barrier at each Poisson arrival time and also reflects from below at 0 in the classical sense.
Student activism in Niger: subverting the ‘limited pluralism’, 1960–83
Authors: Smirnova Tatiana 
Published: January 2019

AbstractThis article revisits the modern political history of Niger during the 1960s to the 1980s through an analysis of relations between student activists and government authorities. It explores how a student organization, the Union des Scolaires Nigériens (USN), managed to bypass multiple layers of political control to become a well-structured political movement, capable of seriously challenging the legitimacy of the authorities. Specifically, the article examines interactions between the USN and different bodies of political power, including the Diori and Kountché governments, in the larger context of regional solidarities and the Cold War. It analyses key moments of this struggle by showing how two generations of student leaders (those of the 1960s to early 1970s and the late 1970 to early 1980s) nourished the creation of specific windows of political action, which found various outlets for expression depending on the form of state power as well as the form and methods of activist work.
Student/teachers from Turfloop: the propagation of Black Consciousness in South African schools, 1972–76
Authors: Heffernan Anne 
Published: January 2019

AbstractThe movement of school teachers to primary and secondary schools around South Africa and its Bantustans in the early and mid-1970s was an intentional part of the project of propagating Black Consciousness to school learners during this period. The movement of these educators played a key role in their ability to spread Black Consciousness philosophy, and in the political forms and methods they chose in teaching it. These were shaped by their own political conscientization and training in ethnically segregated colleges, but also in large part by the social realities of the areas to which they moved. Their efforts not only laid the foundation for Black Consciousness organization in communities across South Africa, they also influenced student and youth mechanisms for political action beyond the scope of Black Consciousness politics. This article explores three case studies of teachers who studied at the University of the North (Turfloop) and their trajectories after leaving university. All of these teachers moved to Turfloop as students, and then away from it thereafter. The article argues that this pattern of movement, which was a direct result of apartheid restrictions on where black South Africans could live, study and work, shaped the knowledge they transmitted in their classrooms, and thus influenced the political consciousness of a new generation.