bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exergoeconomic optimization and sensitivity analysis of a commercial parabolic trough collector for the climate of Tehran, Iran
Authors: Hoseinzadeh Hamed , Kasaeian Alibakhsh , Shafii Mohammad Behshad 
Published: September 2019

AbstractThe exergoeconomic analysis is a powerful tool to study an energy system and provide rational decision‐making for it. This paper is aimed at exergoeconomic optimization and sensitivity analysis evaluation of the results of a commercial parabolic trough collector (PTC). First, an analysis of optical, thermal, exergy, and economic equations of the PTC system is presented. Then, the objective function and variables are optimized through MATLAB software using the hybrid algorithm code. The objective function as the exergy loss rate is a combination of exergy loss and system cost. The evaluation of the results has been carried out considering the radiation intensity in different months of the year for Tehran, Iran. The commercial parabolic trough solar collector has been selected as the case study. Sensitivity analysis of exergy loss rate and exergy efficiency was conducted for important variables, namely collector length, the glass cover diameter, the outer diameter of absorber tube, the inner diameter of absorber, the fluid inlet temperature, the receiver aperture width, and fluid flow rate. The obtained results show that the exergy loss rate is 0.1905 kW/$, and the exergy efficiency is equal to 15.2% for the highest direct solar radiation of 674 .
Experimental study on the overburden movement and stress evolution in multi‐seam mining with residual pillars
Authors: Tian Chenglin , Yang Xuelin , Sun Haitao , Liu Yanbao , Hu Qianting 
Published: September 2019

AbstractWhen faced with multi‐seam mining, some coal pillars are left to support the overlying strata when mining the lower seam, where stress concentration usually occurs. When the working face in the lower seam advances to the area influenced by these coal pillars, high ground pressure behavior occurs. Furthermore, the instability of coal pillars under the participation of the roof may induce rock burst, which threaten the safe production of coal mine. To study the roof strata movement and coal pillar instability in multi‐seam mining, a coal mine in Datong was taken as an example. Firstly, the bursting liability of coal and rock stratum was tested. The test results show that the 7#, 8#, and 11# coal seams in the mining area all have strong bursting liability. And the roof was dominated by siltstone and firestone, which also have strong bursting liability. Then, based on the geological conditions of the coal mine, we investigated roof movement and instability of the coal pillar during multi‐seam mining through physical simulation. The simulation results indicate that multi‐seam mining aggravates the roof damage, which leads to the increase in the fracture range of overlying strata, and that the failure height increases from 46 to 121 m. In addition, the detailed distribution of stress on residual coal pillars and its influence on the lower working face were studied through numerical simulation. The results show that, when the working face 8707 of the 8# coal seam advances to a horizontal distance of 20 m from the coal pillar, it enters the influence zone. As the working face advances beneath the coal pillar, the stress reached to 24 MPa. Moreover, when the working face passes by the coal pillar, the coal pillar is cutoff, thus affecting the working face.
Excavation unloading‐induced fracturing of hard rock containing different shapes of central holes affected by unloading rates and in situ stresses
Authors: Feng Fan , Chen Shaojie , Li Diyuan , Huang Wanpeng , Peng Kang , Zang Chuanwei 
Published: September 2019

AbstractSlabbing failure and strain rock burst are the main failure patterns during the excavation and construction phases of deep tunnels in hard and brittle rock, which cause unexpected equipment damage and casualties. This study presents a numerical simulation with an unloading central hole within a hard rock specimen in the laboratory scale. A combined finite element/discrete element method (FEM/DEM) reproduces the crack initiation, propagation, and coalescence around the central hole during the entire failure process. The influence of sectional shapes, unloading rates of holes, and in situ stresses on the failure characteristics and mechanical response of typical hard and brittle rocks were investigated by analysis of the failure pattern, displacement distribution (average velocity) of monitoring elements, and released strain energy value. The numerical results indicate that the sectional shapes, unloading rates, and in situ stresses have a significant impact on the severity of destruction and failure range in hard rock under the excavation unloading conditions. Slabbing failure (stable failure) is always the dominant failure pattern around a circular hole, which shows higher bearing capacities and self‐stabilization. With the increase in unloading rates, more visible cracks are generated around the holes, and the displacement and average velocity of discrete blocks are further raised. This is particularly evident in rock specimens with holes having vertical walls, leading to intense unstable failure (strain rock burst) accompanied by a large amount of strain energy released. In situ stresses affect considerably the stability of the surrounding rock during the excavation unloading process. With constant in situ stress, the order of destruction severity around the central hole according to its sectional shape is cube > trapezoid > U‐shape > ellipse > circle. The destruction intensity is further aggravated with the increase in lateral pressure coefficient, and the failure regions are always observed in the roof and floor of the central hole. This study confirms that strain rock burst tends to be induced in hard and brittle rock tunnels with polygonal roadway section under high unloading rates and lateral pressure coefficients.
Media reporting of summer drowning: A partial picture, useful for advocacy
Authors: Peden Amy E. , Franklin Richard C. , Willcox‐Pidgeon Stacey 
Published: September 2019

AbstractIssue addressedMedia reporting of drowning deaths can be used for multiple purposes, including advocacy, enhancing data on drowning and supporting policy development. Accurate, current and comprehensive data help ensure the development of effective prevention programs as well as being a tool for advocacy. Advocacy for drowning prevention through the media can create behaviour change aligned to the Health Belief Model (HBM).MethodsThis study compares media reports of fatal unintentional drowning across the 2017/18 Australian summer (1‐December‐2017 to 28‐February‐2018) with drowning cases in the National Coronial Information System (NCIS).ResultsMedia monitoring identified 84 cases, of which nine (11%), were deaths but not drowning. There were 104 NCIS deaths during this time of which 75 were reported in the media (72% capture). Media captured 100% of drowning incidents involving people 0‐24 years and in ocean/harbour locations. Drowning incidents among older people (75+ years; 36% capture), in bathtubs (0% capture), swimming pools (33% capture) and with an unknown activity (27% capture) were poorly reported.ConclusionsWhere there are a lack of timely data on drowning, the use of media can help capture deaths, with limitations. Transmission of messages about drowning risk factors and prevention strategies, during summer, may lead to behaviour change at a time when drowning risk is highest.So what?Working with the media to help enhance advocacy efforts, in particular the development and use of effective drowning prevention messages, is key to informing the public about risk factors in the HBM to achieve behaviour change.
Long non‐coding RNA KDM5B anti‐sense RNA 1 enhances tumor progression in non‐small cell lung cancer
Authors: Lou Baisong , Wei Dongwei , Zhou Xin , Chen Hong 
Published: September 2019

BackgroundThe long non‐coding RNAs (lncRNAs) have been shown as a novel class of transcripts with no protein coding functions. LncRNAs can play diverse roles in cancer cell proliferation, differentiation, metastasis, and apoptosis. However, the exact contributions of lncRNA KDM5B anti‐sense RNA 1 (KDM5BAS1) to non‐small cell lung cancer (NSCLC) remain poorly understood.MethodsIn current study, we have unraveled a novel function of KDM5BAS1 in NSCLC.ResultsWe found that KDM5BAS1 was significantly overexpressed in tumor specimens and selected cancerous cell lines. Meanwhile, higher KDM5BAS1 expression predicted poor overall survival. Increased KDM5BAS1 expression can promote proliferation or migration and inhibit apoptosis in H1838 and H1299 cells. Furthermore, knocking down of KDM5BAS1 levels can also reduce tumor growth in in vivo implantation experiments. Overexpression of KDM5BAS1 also decreased the caspase‐3 immunostaining but enhanced Ki‐67 staining.ConclusionTaken together, our findings indicated that KDM5BAS1 might play an oncogenic role in NSCLC and provided clues into pharmacological intervention targeting KDM5BAS1.
Recurrence of common bile duct stones following laparoscopic common bile duct exploration: a multicenter study
Authors: Park Sun Young , Hong Tae Ho , Lee Sang Kuon , Park Il Young , Kim Tae Hyeon , Kim Sung Geun 
Published: September 2019

AbstractBackgroundRecurrence of common bile duct stone (CBDS) is not common after laparoscopic common bile duct exploration (LCBDE). This study aimed to investigate the risk factors of recurrence of CBDS after LCBDE.MethodsPatients who underwent LCBDE between January 2001 and December 2018 in four teaching hospitals of The Catholic University of Korea were included. The operation, fluoroscopy, and endoscopic retrograde cholangiopancreatography records were investigated retrospectively. The primary outcome of this study was the independent risk factors for recurrence of CBDS.ResultsA total of 230 patients were included in this study. Thirty‐one patients had recurrence of CBDS. In univariate analysis, CBDS size (>9 mm) (P = 0.003), multiple stones (≥2) (P = 0.031), stone size (≥1.5 cm) (P = 0.041), CBD diameter (≥12 mm) (P = 0.005), CBD dilatation (≥10 mm) (P = 0.02), prior history of laparoscopic cholecystectomy (P = 0.002) were associated with recurrence. After multivariable logistic regression, CBDS size (>9 mm) (OR 4.67, 95% CI 1.35–16.18, P = 0.011), CBD dilatation (≥10 mm) (OR 5.66, 95% CI 1.47–21.82, P = 0.012), and prior history of laparoscopic cholecystectomy (AOR 3. 90, 95% CI 1.34–11.37, P = 0.013) were associated with recurrence.ConclusionsStone size >9 mm, CBD diameter ≥10 mm, and prior history of laparoscopic cholecystectomy were risk factors for recurrence of CBDS after LCBDE.
Hospital volume and mortality in liver resections for colorectal metastasis using population‐based administrative data
Authors: Hunger Richard , Mantke Anne , Herrmann Christian , Grimm Alexis Leonhard , Ludwig Juliane , Mantke René 
Published: September 2019

AbstractBackgroundApproximately one‐quarter of patients with colorectal carcinoma develop colorectal liver metastases (CRLM). Surgical treatment with curative intent by hepatic resection is the standard medical care. While some studies with small sample sizes have investigated the relationship between hospital procedure volume and in‐hospital mortality for this diagnosis, no population‐based study has been conducted. The present study was aimed at closing this gap.MethodsBased on administrative population‐based hospital discharge data (Diagnosis Related Group Statistic), patients diagnosed with CRLM and treated with hepatic resection from 2011 to 2015 were identified. The hospital operation‐volume effect on risk‐adjusted in‐hospital mortality was examined by logistic regression models.ResultsDuring the study period, 5900 patients with CRLM were treated with hepatic resection, of whom 189 (3.2%) died before hospital discharge. Hospitals of different operation‐volume quartiles did not differ in terms of mortality rates. Sensitivity analysis investigating the volume–mortality relationship separately for every resection procedure showed no clear result. Procedure frequencies vary among hospitals of different volume quartiles, with low‐volume hospitals performing systematically more low‐risk procedures (in terms of reduced mortality rate), than high‐volume hospitals.ConclusionBased on almost complete German hospital discharge data, the results did not confirm unconditional volume–outcome relationship for CRLM patients.
Novel single‐layer continuous suture of pancreaticojejunostomy for robotic pancreaticoduodenectomy
Authors: Liu Qu , Zhao Zhiming , Gao Yuanxing , Zhao Guodong , Tan Xianglong , Wang Chihyuan , Liu Rong 
Published: September 2019

AbstractBackgroundThe best technique for pancreatic anastomosis after pancreaticoduodenectomy (PD) remains controversial, and the procedure for robotic PD (RPD) has not been previously reported. This study aimed to evaluate the safety and feasibility of a novel technique of pancreaticojejunostomy (PJ) for RPD.MethodsThe demographics and perioperative outcomes of a consecutive series of RPD patients who underwent single‐layer continuous suture (SCS) for PJ between September 2018 and November 2018 were analyzed.ResultsThirty patients were included in the study. Twenty patients had a soft pancreas, and 15 patients had a small main pancreatic duct (MPD) (<3 mm). The mean operative time was 234.1 min, the mean duration of PJ was 14.9 min, and the median estimated blood loss was 100.0 ml. No patients required conversion to laparotomy. Postoperative pancreatic fistula (POPF) included seven cases of Grade A and two cases of Grade B. No case of Grade C POPF occurred. The mean postoperative hospital stay was 12.3 days. No 90‐day readmission or mortality was observed. Neither pancreatic texture nor MPD size affected the perioperative outcomes.ConclusionsSingle‐layer continuous suture is easy to perform and is associated with favorable clinical outcomes, regardless of the pancreatic duct size and texture.
Effects of a toothpaste containing 0.3% triclosan on periodontal parameters of subjects enrolled in a regular maintenance program: A secondary analysis of a 2‐year randomized clinical trial
Authors: Stewart Bernal , Shibli Jamil Awad , Araujo Mauricio , Figueiredo Luciene Cristina , Panagakos Fotinos , Matarazzo Flavia , Mairink Renata , Onuma Tatiana , Faveri Marcelo , Retamal‐Valdes Belén , Feres Magda 
Published: September 2019

AbstractBackgroundThe triclosan‐containing dentifrices are effective in controlling biofilm formation and maintaining gingival health; however, there is limited information on their effects during the periodontal maintenance phase. Therefore, the aim of this study was to evaluate the clinical effects of a toothpaste containing 0.3% triclosan on the periodontal parameters of subjects that have been treated for peri‐implantitis and were enrolled in a regular maintenance program.MethodsSubjects presenting at least one implant with peri‐implantitis and received surgical anti‐infective therapy were selected. Sixty days post‐surgery (baseline), subjects were randomized into two groups: (1) toothpaste containing 0.3% triclosan + 2.0% PVM/MA copolymer + 1450 ppm fluoride (test) or (2) toothpaste containing 1450 ppm fluoride (control), and were instructed to brush with the assigned toothpaste twice/day for 2 years. They received clinical monitoring at baseline, 3, 6, 12, 18, and 24 months, and professional maintenance every 3 months.ResultsEighty‐eight subjects with natural teeth were enrolled in the study (Test, n = 39; Control, n = 49). The test group showed a greater reduction in the percentage of sites exhibiting bleeding on probing (primary outcome) and lower levels of plaque in comparison with the control group after 24 months (P < 0.05). The mean percentage of sites with probing depth ≥5 mm was reduced over the course of the study only in the test group (P < 0.05).ConclusionA toothpaste containing 0.3% triclosan was more effective than a regular fluoride toothpaste in improving the periodontal clinical condition around natural teeth of periodontally healthy subjects enrolled in a regular maintenance program for 2 years.
Subepithelial connective tissue graft with or without enamel matrix derivative for the treatment of multiple Class III‐IV recessions in lower anterior teeth: A 3‐year randomized clinical trial
Authors: Mercado Faustino , Hamlet Stephen , Ivanovski Saso 
Published: September 2019

AbstractBackgroundThis study compared clinical and patient‐centered outcomes of subepithelial connective tissue graft (CTG) with and without enamel matrix derivative (EMD) in the treatment of multiple Class III‐IV Miller periodontal recession (REC) defects on mandibular anterior teeth.MethodsThis randomized clinical study evaluated 41 patients at 3 years follow‐up. One hundred and fifty‐six teeth were divided into two groups: test (CTG‐EMD, 79 teeth) and control (CTG only, 77 teeth). Clinical REC, keratinized tissue (KT) width, percentage of root coverage, patient‐centered outcomes were compared between the two groups.ResultsAt 36 months follow‐up, patient level analysis showed that REC in the test group reduced significantly (5.71 ± 0.58 mm to 1.57 ± 0.85 mm) compared with the control group (5.94 ± 0.46 mm to 2.51 ± 0.62 mm) (P < 0.001), while KT width increased in the test group (1.51 ± 0.26 mm to 4.18 ± 0.34 mm) and was significantly greater than the control group (1.65 ± 0.21 mm to 2.90 ± 0.20 mm) (P < 0.001). At 36 months, tooth level analysis (Class III and Class IV groups) found less residual REC and increased KT in the test group compared with the control group (P < 0.01). Significantly less pain was reported at 2, 7, and 14 days follow‐up post‐surgery in the test group (P < 0.001).ConclusionsThe addition of EMD to CTG results in improved root coverage outcomes and higher amounts of KT width 36 months after treatment of Class III‐IV REC on mandibular anterior teeth. The adjunctive use of EMD also resulted in significantly reduced pain 14 days post‐surgery.
The effect of radical cystectomy on survival in patients with metastatic urothelial carcinoma of the urinary bladder
Authors: Luzzago Stefano , Palumbo Carlotta , Rosiello Giuseppe , Pecoraro Angela , Deuker Marina , Tian Zhe , Shariat Shahrokh F. , Saad Fred , de Cobelli Ottavio , Karakiewicz Pierre I. 
Published: September 2019

AbstractBackgroundTo test the effect of radical cystectomy (RC) with chemotherapy vs only chemotherapy on overall mortality (OM) in metastatic urothelial carcinoma of the urinary bladder (mUCUB).MethodsWithin the Surveillance, Epidemiology, and End Results registry (2004–2016), we identified patients with mUCUB. Stratification was made according to treatment: RC with chemotherapy vs only chemotherapy. Kaplan‐Meier plots and multivariable Cox regression models were used before and after 1:1 propensity score (PS) matching and inverse probability of treatment weighting (IPTW).ResultsOf 2414 patients with mUCUB, 500 (21.0%) vs 1914 (79.0%) were treated with RC with chemotherapy vs only chemotherapy, respectively. In multivariable Cox regression models, RC with chemotherapy was associated with lower OM in the overall cohort (hazard ratio [HR], 0.5; P < .001), after 1:1 PS matching (HR, 0.5; P < .001), after IPTW (HR, 0.5; P < .001) and after accounting for number and location of metastases (HR, 0.5; P < .001). However, higher overall survival after RC with chemotherapy was only observed in patients with one metastatic site (21 vs 16 months; P = .001).ConclusionIn contemporary patients with mUCUB, RC with chemotherapy is associated with lower OM rates, relative to chemotherapy alone, but only in patients with a single metastatic site. These individuals accounted for the vast majority of patients in whom an RC was performed, despite the presence of metastatic disease.
Facile enantioseparation and recognition of mandelic acid and its derivatives in self‐assembly interaction with chiral ionic liquids
Authors: Cai Pengfei , Gao Zhan , Yin Xinchi , Luo Yuanqing , Zhao Xiaoyong , Pan Yuanjiang 
Published: September 2019

AbstractMandelic acid and its derivatives are important medical intermediates in the pharmaceutical industry. Different stereoisomers exhibited distinct biological properties to human bodies. Given that, enantioselective recognition and separation of mandelic acid are of great importance. In this study, four novel different types of chiral ionic liquids bearing designed functional groups were synthesized and successful enantioselective precipitation with mandelic acid and its derivatives. That is, (R, R)‐chiral ionic liquid 1 can coprecipitated with S‐mandelic acid and its derivatives was observed. In addition, good correlation coefficient is achieved by using electrospray mass spectrum at negative ion pattern for quick analysis of the enantioselective precipitation, which could be served as a method of enantioselective recognition. The possible intermolecular interactions are established after systematical studies by NMR spectroscopy and DFT calculations.
Biliary Complications After Liver Transplantation From Uncontrolled Donors After Circulatory Death: Incidence, Management, and Outcome
Authors: Jiménez‐Romero Carlos , Manrique Alejandro , García‐Conde María , Nutu Anisa , Calvo Jorge , Caso Óscar , Marcacuzco Alberto , García‐Sesma Álvaro , Álvaro Edurne , Villar Roberto , Aguado José María , Conde María , Justo Iago 
Published: September 2019

The utilization of livers from donation after uncontrolled circulatory death (uDCD) increases the availability of liver grafts, but it is associated with a higher incidence of biliary complications (BCs) and lower graft survival than those organs donated after brain death. From January 2006 to December 2016, we performed 75 orthotopic liver transplantations (OLTs) using uDCD livers. To investigate the relationship of BCs with the use of uDCD OLT, we compared patients who developed BCs (23 patients) with those who did not (non‐BC group, 43 patients) after excluding cases of hepatic artery thrombosis (a known cause of BC) and primary nonfunction. The groups had similar uDCD donor maintenance, donor and recipient characteristics, and perioperative morbidity/mortality rates, but we observed a higher rate of hepatocellular carcinoma and hepatitis C virus in the non‐BC group. Percutaneous transhepatic biliary dilation, endoscopic retrograde cholangiopancreatography dilation, Roux‐en‐Y hepaticojejunostomy (HJ), a T‐tube, and retransplantation were used for BC management. In the BC group, 1‐, 3‐, and 5‐year patient survival rates were 91.3%, 69.6%, and 65.2%, respectively, versus 77.8%, 72.9%, and 72.9%, respectively, in the non‐BC group (P = 0.89). However, 1‐, 3‐, and 5‐year graft survival rates were 78.3%, 60.9%, and 56.5%, respectively, in the BC group versus 77.8%, 72.9%, and 72.9%, respectively, in the non‐BC group (P = 0.38). Multivariate analysis did not indicate independent risk factors for BC development. In conclusion, patient and graft survival rates were generally lower in patients who developed BCs but not significantly so. These complications were managed in the majority of patients through radiological dilation, endoscopic dilation, or Roux‐en‐Y HJ. Retransplantation is necessary in rare cases after the failure of biliary dilation or surgical procedures.