bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Model Pembelajaran “GREATER” pada Pembelajaran Kimia sebagai Upaya Penanaman Literasi Sains Peserta Didik
Authors: Fahmawati Diah 
Published: September 2019

<strong>Development of "Greater" Learning Model on Chemistry Learning as an Effort to Embed Students' Science Literacy. </strong>This study aimed producing a learning models named GREATER (Gear Up, Read, Explore, Analyze, Tell, Elaborate, Reflection) to foster the scientific literacy. The research method was Research and Development used simplified Borg and Gall consisting of two stages, research and development. Phase I includes 1) a field study and 2) study of literature producing factual models. Phase II includes 1) planning the design of the product, 2) validation expert, 3) revision I, 4) small-scale trials, 5) revision II, 6) a limited scale trials and 7) effectiveness test. The products included manual book, lesson plans, worksheets, reading material and KWHLAQ chart and achievement test. The research population were one class in SMA PGRI 1 Maospati and two classes in SMAN 1 Sukomoro. The instrument were the scientific literacy test, observation sheets, questionnaires. The results showed 1) expert validatition was obtained a valid scores meaning that the model was considered feasible to be applied in classroom setting. 2) empirically, showed the pretest and post score showed increase from 35.16% to 62.23% of students who answered correctly, while the percentage of students who answered “do not know” down from 19.43% to 12.63%. Model GREATER effective at improving the student’s scientific literacy and they become more familiar with the scientific phenomena, variable scientific investigation and interpreting data.
Profil Keterampilan Proses Sains Fisika Siswa SMA di Kota Lubuklinggau pada Pokok Bahasan Listrik Dinamis
Authors: Yolanda Yaspin , Amin Ahmad 
Published: September 2019

Penelitian ini bertujuan mendeksripsikan profil keterampilan proses sains (KPS) fisika siswa di SMA Kota Lubuklinggau pada materi listrik dinamis. Subjek penelitian adalah siswa SMA kelas XII semester ganjil di sma Negeri 1, MAN 1 Model dan SMA Negeri 5 di Lubuklinggau. Pengambilan sampel dilakukan secara <em>purpossive sampling. </em>Metode Deskriptif kualitatitif. Data dianalisa secara kualitatif dan kuantitatif. Berdasarkan hasil data penelitian KPS fisika siswa kelas XII IPA pada pokok bahasan Listrik Dinamis disimpulkan (1) Keterampilan proses sains fisika siswa kelas XI IPA pada pokok bahasan suhu dan kalor di MA Al-Muhajirin Tugumulyo adalah terampil, dan (2) Solusi untuk menyelesaikan permasalahan ketersediaan aspek KPS adalah melatih dan dilatih dengan pendekatan KPS fisika siswa agar ketersediaan aspek KPS siswa dapat muncul/tersedia. Adapun aspek KPS yang perlu dilatih dan melatih adalah keterampilan klasifikasi, mengkomunikasikan, berhipotesis, menerapkan konsep, bereksperimen, menggunakan alat dan bahan, interprestasi dan mengajukan pertanyaan. Persentase peningkatan KPS yakni, keterampilan observasi 90,3%, keterampilan klasifikasi 85,3%, keterampilan interpretasi 87,2%, keterampilan prediksi 80,4 %, keterapilan merencanakan percobaan atau penyelidikan 92,6%, keterampilan menggunakan alat dan bahan 92,1%, keterampilan menerapkan konsep atau prinsip 82,3%, keterampilan berkomunikasi 89,4%, keterampilan mengajukan pertanyaan 95,1%, dan keterampilan berhipotesis 81,2%. Sehingga secara keseluruhan terjadinya peningkatan yang signifikan 87,3% KPS siswanya.
Model Pembelajaran Berbasis Pengalaman untuk Meminimalkan Miskonsepsi Siswa pada Materi Cahaya
Authors: Budhi Henry Setya 
Published: September 2019

Penelitian ini bertujuan untuk menguji penggunaan model pembelajaran berbasis pengalaman dalam pembelajaran materi cahaya dan mendeskripsikan efektivitasnya dalam meminimalkan terjadinya miskonsepsi. Metode penelitian yang digunakan adalah eksperimen semu dan deskriptif. Kajian difokuskan pada tingkat miskonsepsi siswa kelas VIII Semester 2. Pengumpulan data dilakukan dengan <em>postest</em> untuk mengetahui tingkat miskonsepsi siswa setelah pembelajaran dengan menggunakan tes diagnostik bermetode CRI (<em>Certainty of Response Indeks</em>). Hasil penelitian menunjukkan penggunaan model pembelajaran berbasis pengalaman pada materi cahaya secara signifikan lebih dapat meminimalkan miskonsepsi siswa dibandingkan dengan penggunaan model pembelajaran konvensional. Hal ini dapat dilihat dari skor rata-rata<em> posttest</em> miskonsepsi untuk kelas eksperimen sebesar 9, sedangkan untuk kelas kontrol sebesar 32.
Penerapan Pembelajaran Dengan Metode Mindmapping Menggunakan Coggle ™
Authors: Dewantara Dewi 
Published: September 2019

<span>Artikel ini bertujuan untuk mendeskripsikan ada atau tidaknya perbedaan antara hasil belajar sebelum dan setelah menerapkan pembelajaran dengan metode mindmapping menggunakan Coggle ™. Jenis penelitian ini adalah pre-eksperimen dengan metode one group pre-test post-test design. Jumlah sampel penelitian adalah 15 orang mahasiswa.<span> </span>Teknik<span> </span>pengumpulan data adalah dengan menggunakan pre-test dan post-test. Data dianalisis dengan menggunakan uji-t berpasangan. Hasil analisis uji-t diperoleh nilai t= -5,985 dengan sig (2-tailed) = 0,000 yang lebih kecil dari taraf signifikansi yakni 0,05. Simpulan dari hasil penelitian ini adalah terdapat perbedaan antara hasil belajat mahasiswa sebelum dan setelah menerapkan Pembelajaran dengan metode mindmapping menggunakan Coggle ™.</span>
Determination of the relationship between some morphological traits of the tomato lines and resistance tomato yellow leaf curl virus disease
Authors: Zengin Sinan , Kabaş Aylin , İlbi Hülya 
Published: September 2019

Abstract
Background: Tomato ( Solanum lycopersicum L.) is the most produced and exported vegetable in Turkey. There are many pathogens to limit tomato production by reducing yield and fruit quality. Among them, Tomato Yellow Leaf Curl Virus (TYLCV) causes important economic losses. The most efficient and environmental friendly method against TYLCV is the use of resistant varieties. In this trial, it was aimed to determine some morphological traits which were linked to Ty-1 and Ty-3a genes which confer to TYLCV. A commercial hybrid carrying Ty-1, Ty-3a genes as heterozygous was crossed to a susceptable inbred line from Bati Akdeniz Agricultural and Research Institute (BATEM). Marker assisted selection (MAS) was carried out in F 1 and F 2 generations and biological tests were done for TYLCV resistance in F 3 generation. MAS for Ty-3a and Ty-1 genes were compatible with biological tests.
Complete Genome Sequence of Sphingobacterium sp. Strain CZ-2T Isolated from Tobacco Leaves Infected with Wildfire Disease
Authors: Cai Xunhui , Wang Ruyi , Hu Shengnan , Li Ying , Chen Tao , He Jianyun , Tan Siqiao , Zhou Wei 
Published: September 2019

Abstract
Background Sphingobacterium is a class of Gram-negative, non-fermentative bacilii, and rarely involved in human infections. It is characterized by a large number of cellular membrane sphingophospolipids. Due to its wide ecological distribution and oil degradation ability, environmental microbiologists have paid much attention to it. Results A novel gram-negative bacterium, designated CZ-2 T , was isolated from a sample of tobacco leaves infected with wildfire disease in Guiyang County, Chenzhou City, Hunan Province, China, and its phylogenetic position was investigated by GC content determination, PCR amplification, sequencing and phylogenetic analysis. Growth occurred on TGY medium at 30 °C and pH 7.0. The GC content of the DNA of strain CZ-2 T is 40.68 mol%. Genome relatedness, rDNA phylogeny and chemotaxonomic characteristics all indicate that strain CZ-2 T represents a novel species of the genus Sphingobacterium . We propose the name Sphingobacterium. tobaci sp. nov., with CZ-2 T as the type strain. Third-generation sequencing (TGS) and next-generation sequencing (NGS) were used to derive a finished genome sequence for strain CZ-2 T , consisting of a circular chromosome 3,925,977 bp in size. The genome of strain CZ-2 T features 3,462 protein-encoding and 50 tRNA-encoding genes. Unigenes were annotated by matching against Clusters of Orthologous Groups of proteins (COG; 2,021 genes), Gene Ontology (GO; 1,952 genes) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases (1,380 genes). Comparison of the predicted proteome of CZ-2 T with those of other Sphingobacterium identified 677 species-specific proteins that may contribute to the adaptation of CZ-2 T to its native environment. Conclusions As the first report of a Sphingobacterium genome sequenced by NGS and TGS, our work will serve as a useful reference for subsequent sequencing and mapping efforts for additional strains and species within this genus.
The Oxidoreductase DsbA1 negatively influences 2,4-diacetylphloroglucinol biosynthesis by interfering the function of Gcd in Pseudomonas fluorescens 2P24
Authors: Wu Xiaogang , Zhang Bo , Zhao Hui , Zhang Li-Qun 
Published: September 2019

Abstract
The polyketide antibiotic 2,4-diacetylphloroglucinol (2,4-DAPG), produced by Pseudomonas fluorescens 2P24, is positively regulated by the GacS-GacA two-component system. Here we reported on the characterization of DsbA1 (disulfide oxidoreductase) as novel regulator of biocontrol activity in P. fluorescens . Our data showed that mutation of dsbA1 caused the accumulation of 2,4-DAPG in a GacA-independent manner. Further analysis indicated that DsbA1 interacts with membrane-bound glucose dehydrogenase Gcd, which positively regulates the production of 2,4-DAPG. Mutation of cysteine (C)-235, C275, and C578 of Gcd, significantly reduced the interaction with DsbA1, enhanced the activity of Gcd and increased 2,4-DAPG production. Taken together, our results suggest that DsbA1 regulates the 2,4-DAPG concentration via fine-tuning the function of Gcd in P. fluorescens 2P24.
Association of a polymorphism in SREBP1 with fatty acid composition and lipogenic gene expression in beef cattle breeds
Authors: Gamarra David , Aldai Noelia , Arakawa Aisaku , Pancorbo Marian M. de , Taniguchi Masaaki 
Published: September 2019

Abstract
Background Sterol regulatory element-binding protein 1 (SREBP1) plays an important role in the lipogenesis and fatty acid (FA) composition in fat cells and is consequently considered to influence the nutritional quality of beef. SREBP1 regulates lipogenic gene transcription including stearoyl-CoA desaturases (SCDs) that are responsible for unsaturation of FAs. Therefore, we performed phylogenetic analysis on SREBP1 gene sequences, including 84 bp-indel, among mammals to elucidate the evolutionary importance of this polymorphism and possible effect in the FA composition. Additionally, we analyzed the association between the indel, FA composition, and gene expression of SREBP1 and SCDs in backfat of several commercial type beef breeds in northern Spain (Pirenaica, Salers and Holstein-Friesian).Results In ruminants, the indel region was relatively highly conserved in comparison with the rest of intron 5 sequence or mRNA of SREBP1, suggesting the potential functionality throughout evolution. We applied the definition of the insertion and deletion of 84 bp in intron 5: S (Short) and L (Long) alleles, respectively. Then, we figured the indel is associated with saturated FA (SFA) and several polyunsaturated FA (PUFA) depending on commercial type, specifically Pirenaica bulls, whose SS/SL genotype has been associated with a higher content of 18:0, n-3 and 18:3n-3 (p < 0.05). In Salers, S allele showed the highest frequency (0.385) among all breeds, while SS genotype had high positive correlations between SREBP1 gene expression and UFA contents. Significant correlations between SCD1 and SFAs (16:0) in SL genotype of Pirenaica bulls, but also 9c-16:1 in Pirenaica breed (p < 0.05), suggests a differential relationship between SCD1 and 16:0/9c-16:1 FA contents depending on the indel genotype in this breed. Overall, SS and SS/SL genotypes had a positive correlation between SCD5 and 18:0 (p < 0.05) and a negative correlation between SCD5 and 9c-18:1 (p > 0.05).Conclusions These results suggest that the indel is associated with SFA and PUFA content depending on commercial type. Moreover, the correlations between lipogenic genes (SREBP1 and SCDs) with 16:0 and 9c-16:1, but also 18:0 and 9c-18:1, seems to be attributed to the indel genotype. These findings are useful for beef/dairy breeding to supply nutritionally favorable products.
The association of sleep problems in children with autism and parental quality of life
Authors: Liu Ruiting , Dong Huixi , Wang Ying , Lu Xiaozi , Li Yamin , Xun Guanglei , Xia Kun , Zhao Jingping , Ou Jianjun , Shen Yidong 
Published: September 2019

Abstract
Background Many children with autism suffer from sleep problems that impact not only children’s daytime behavior and cognitive development but also their parents’ life and health. The current study explored how and to what extent sleep problems in children with autism spectrum disorder (ASD) impacted their parents’ quality of life (QOL).Methods This study adopted a case-control study design. A total of 440 ASD children aged 4 to 10 years and 344 age-matched typically developing (TD) children were included in the study. The Children’s Sleep Habits Questionnaire (CSHQ) was used to measure sleep problems in the enrolled children, and parental QOL was measured by the Short Form 36 Health Survey Questionnaire Version 2.0 (SF-36v2). Linear regression and pathway analysis were used to explore the impact of children’s sleep problems on parental QOL.Results The linear regression model showed that the CSHQ total scores were negatively associated with maternal mental health summary (MCS) scores (β=-2.831, p=0.005) in the TD group. In the ASD group, the CSHQ total scores were negatively associated with the parental physical health summary (PCS) scores (β=-3.030, p=0.003 for mothers, β=-3.651, p<0.001 for fathers) after adjusting for the child’s age, parental age, parental Zarit Caregiver Burden Interview (ZBI) score and Social Responsiveness Scale (SRS) score as covariates. The pathway analysis indicated that sleep problems in ASD children had both direct and indirect effects on maternal PCS.Conclusion The main results of the current study showed that sleep problems in children with or without ASD may affect parental QOL in different ways, and ASD children’s sleep problems affect parental physical health as a risk factor independent from the social impairments associated with ASD and the childcare burden of the parents.
Knowledge, Attitude and Practice of Mothers on Prevention and Control of Intestinal Parasitic Infestations in Sekota Town, Waghimra Zone, Ethiopia
Authors: Kassaw Mesfin Wudu , Abebe Ayele Mamo , Abate Biruk Beletew , Zemariam Alemu Birara , Kassie Ayelign Mengesha 
Published: September 2019

Abstract
Background Intestinal parasites were a major public health problem in many developing countries. It accounts for 1.5 billion infections with one or more causative agents. The national prevalence of helminthiasis in Ethiopia was 29.8% with considerable variability across the different regions. Young children had a high infection rate and suffered with a substantial worm burden of A. lumbricoides, trichuris trichiura and schistosomes . Parasitic infection has also serious consequences on human health, such as hepatomegaly, bleeding, esophageal varices, delay in physical development. It also decrease the immunity system, level of intelligence, and labor productivity. Therefore, this study was intended to assess mothers’ knowledge, attitude and practice on prevention and control of intestinal parasitic infection among their preschool children in Sekota town, Waghimra zone, EthiopiaMethods A cross sectional study was carried out on 378 mothers who had under six years but over two years old children. Although, 384 mothers were selected using sample size calculation in the year 2019, the data was collected from 378 mother-child pairs. A face to face interview was performed using pretested and structured questionnaire in the urban villages, Sekota town. The level of maternal knowledge, attitude and practice were presented in percentage, frequency and table. Results The overall level of good knowledge or knoledgable, positive attitude and good practice of mothers towards intestinal parasites prevention and control in considering their preschool children in Sekota town was 45.2%, 55.3% and 51.1% respectively. Seventy seven 77(20.4%) respondents reported that they knew Ascaris Lumbricoids , 62 (16.4%) participants wash vegetables as a means of intestinal prevention, and 252 (66.7%) of participants stated that their children had at least one stool examination previously.Conclusions The overall level of optimum knowledge, attitude and practice of mothers on prevention and control of intestinal parasites is low. In particular, the level of optimal knowledge is very low in this study. According to the median parameter, 50% and above of mothers had both positive attitude and good practice. But mothers who were knowledgeable fall below 50%. Therefore, community awareness about intestinal parasitic infestations prevention and control should be created with special emphasis on mothers.
Predictive factors for developing acute cholangitis and cholecystitis in patients undergoing delayed cholecystectomy: a retrospective study
Authors: Miyata Takashi , Matsui Daisuke , Fujiwara Yuta , Saito Hiroto , Ohbatake Yoshinao , Nishijima Koji , Miyashita Tomoharu , Futagami Fumio , Nakamura Takashi , Takamura Hiroyuki 
Published: September 2019

Abstract
Background We evaluated the risk of acute cholangitis and cholecystitis while waiting for cholecystectomy for gallstones. Methods We retrospectively enrolled 168 patients who underwent cholecystectomy for gallstones after a waiting period and conservative therapy between April 2014 and March 2018 at our hospital. We compared the clinical data from 20 patients who developed acute cholangitis and cholecystitis while waiting for cholecystectomy (group A) with data from 148 patients who did not develop cholangitis and cholecystitis (group B). The risk factors for developing acute cholangitis and cholecystitis and all patients' surgical outcomes were investigated. Results Preoperatively, significant differences in age (68.6 years vs 60.7 years; p= 0.004) and the number of patients with a previous history of acute grade II or III cholecystitis (55.0% vs 10.8%; p< 0.001) and biliary drainage (20.0% vs 2.0%; p= 0.004) were observed between group A and group B, respectively. Preoperative white blood cell counts (13500/µL vs 8155/µL; p< 0.001) and serum C-reactive protein levels (12.6 mg/dL vs 5.1 mg/dL; p< 0.001) were significantly increased, and serum albumin levels (3.2 g/dL vs 4.0 g/dL; p< 0.001) were significantly decreased in group A vs group B, respectively. Gallbladder wall thickening (≥ 5 mm) (45.0% vs 18.9%; p= 0.018), incarcerated gallbladder neck stones (55.0% vs 22.3%; p= 0.005), and abscess around the gallbladder (20.0% vs 1.4%; p= 0.002) were seen significantly more frequently during imaging in group A vs group B, respectively. Furthermore, investigating patients' surgical outcomes revealed a higher conversion rate to open surgery (20.0% vs 2.0%; p= 0.004), longer operation time (137 min vs 102 min; p< 0.001), and a higher incidence of intraoperative complications (10.0% vs 0%; p= 0.014) in group A vs group B, respectively. Conclusions Our results suggest that a history of severe cholecystitis is a risk factor for developing acute cholangitis and cholecystitis in patients waiting for surgery, and a risk factor for increased surgical difficulty.
Impact of preoperative fecal short chain fatty acids on postoperative infectious complications in esophageal cancer patients
Authors: Motoori Masaaki , Tanaka Koji , Sugimura Keijiro , Miyata Hiroshi , Saito Takuro , Miyazaki Yasuhiro , Fujitani Kazumasa , Kado Yukiko , Asahara Takashi , Yano Masahiko 
Published: September 2019

Abstract
Background: The intestinal epithelial barrier allows absorption of dietary nutrients and prevents passage of pathogens and toxins into the body. Severe insults have a negative impact on the intestinal environment, which may decrease intestinal barrier function and cause bacterial translocation. Bacterial translocation, which can cause infectious complications, is the passage of microbes from the gastrointestinal tract across the mucosal barrier to extraintestinal sites. The aim of this study was to investigate the correlation between concentrations of preoperative fecal organic acids and the occurrence of postoperative infectious complications in patients with esophageal cancer. Methods: Fifty-five patients with esophageal cancer who underwent esophagectomy were enrolled in this study. All patients were administered perioperative synbiotics. Perioperative clinical characteristics and concentrations of preoperative fecal organic acids were compared between patients with or without postoperative infectious complications. Results: Postoperative infectious complications occurred in 10 patients. In patients with complications, the concentrations of acetic acid and propionic acid were significantly lower than in patients without complications (p=0.044 and 0.032, respectively). The concentration of butyric acid was nonsignificantly lower, while the concentration of lactic acid was nonsignificantly higher in patients with complications. The calculated gap between the concentrations of fecal acetic acid plus propionic acid plus butyric acid minus lactic acid was significantly lower in patients with complications. Multivariate analysis revealed that a low gap between acetic acid plus propionic acid plus butyric acid minus lactic acid was an independent risk factor for postoperative infectious complications (p=0.027). Conclusions : Preoperative fecal concentrations of organic acids had a clinically important impact on the occurrence of postoperative infectious complications in patients with esophageal cancer. To reduce postoperative infectious complications, it may be useful to modulate the intestinal environment and maintain concentrations of fecal organic acids before surgery.
Consultation-dependent motivation to self-management in adolescents with type 1 diabetes: a qualitative triangulation study
Authors: Teyken Rose Marie , Lomholt Johanne Jeppesen , Schou Anders Jørgen 
Published: September 2019

Abstract
Background. The impact of health care professionals on the motivation for self-management in adolescents with type 1 diabetes has been highlighted as important. It is, however, not well understood how pediatric diabetes health care practitioners can help adolescents become more motivated to self-management. The aim of the study was to investigate how practitioners can motivate their patients to self-management in consultation and how adolescents with type 1 diabetes experienced consultation-dependent motivation to self-management. Methods. Based on a qualitative research design, the study triangulated participant observations of 11 consultations at a pediatric health care clinic and 10 interviews of the adolescents (15-17 years of age) about their experiences of consultations. Using Giorgi’s phenomenological method, the analysis showed five categories important to consultation-dependent motivation to self-management: 1. Consultation setting, 2. Consultation conversation, 3. Roles in treatment, 4. Assuming consultation-dependent responsibility for self-management, and 5. Relationship in treatment. Results from the analysis were compared to fulfilment of the motivational needs for autonomy, competence and relatedness described in Self-Determination Theory. Results. Overall findings showed that the adolescent’s developmental process of becoming autonomous in relation to self-management was influenced by consultations, and that the need for relatedness was experienced as valued by the adolescents. Conclusions. The conclusion of the study was that relatedness and development of autonomy were experienced as important for consultation-dependent motivation to self-management in 15-17-year-olds and may be fundamental to adolescents’ experience of competence in relation to self-management.