bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical nurse specialist prescribing in a cancer centre supportive and palliative care team
Authors: Hall Sally , Thompson Jo , Phair Toni , Davies Andrew Neil 
Published: August 2019

ObjectiveTo provide insight into the prescribing practices of three independent nurse prescribers (INPs)/clinical nurse specialists (CNSs) working in a supportive and palliative care team (SPCT) in a district general hospital and a specialist tertiary cancer centre in the UK.MethodsA prospective review of all consultations and the prescribing activity arising from the consultations (and reasons for non-prescribing following a consultation) of 3 INPs/CNSs between 1 August 2018 and 31 October 2018.ResultsFour hundred ninety-three consultations were undertaken on 186 individual patients. Two hundred forty-seven consultations representing 50% resulted in changes to a prescription, and 123 of those consultations representing 50% of prescriptions written resulted in the prescribing of an opioid for moderate-to-severe pain.ConclusionsThis service evaluation demonstrates the potential for INPs in SPCTs to provide comprehensive symptom control while enabling CNSs to practice with a greater degree of autonomy leading to enhanced job satisfaction. On the basis of our experience, we would encourage all palliative care CNSs to undergo training to become INPs (if available).
Non-suicidal self-injury in Shanghai inner bound middle school students
Authors: Zhang Fang , Cloutier Paula F , Yang Hongmei , Liu Wenjing , Cheng Wenhong , Xiao Zeping 
Published: August 2019

BackgroundNon-suicidal self-injury (NSSI) behaviour is very common among adolescents. Its prevalence and behavioural characteristics may vary according to regional and cultural differences. Investigation of NSSI locations and diagnosis of adolescents with NSSI are relatively lacking in China.AimsThe study objective was to determine the prevalence and features of NSSI among middle school students in Shanghai.MethodsThe participants were from grade 6 to 8 selected from three junior schools in Jing’an District. Consenting students completed the Ottawa Self-Injury Inventory to determine the prevalence and characteristics of NSSI. Those who indicated NSSI within the past month were administered the Mini-International Neuropsychiatric Interview for Children and Adolescents to assess for emotional disorders.ResultThe result shows 510 participants (21.7%; mean age 13.51 (0.97) years old; 56.7% female) reported at least one instance of NSSI during the previous 12 months. NSSI was significantly more common in girls than boys (24.9% vs 18.5%; χ2=14.03, p=0.00). Commonly reported reasons for NSSI were for internal and external emotion regulation (87.9%, 82.3%) and social influence (57.8%). Anxiety disorders were the most common (28.9%) disorder associated with NSSI.ConclusionThe rate of NSSI of middle school students in Shanghai inner bound is similar to those reported in North American and European youth. It is essential that school mental health professionals are aware of how to manage NSSI within the school setting.
Charting New Paths in Modern-Critical Exegesis: An Agrarian-Rhetorical Analysis of Isaiah 5
Authors: Stulac Daniel J. D. 
Published: August 2019

AbstractFollowing the work of Ellen Davis in her 2009 volume Scripture, Culture, and Agriculture: An Agrarian Reading of the Bible, this essay identifies an “agrarian hermeneutic” as an important resource for addressing current impasses in modern-critical exegesis. A close examination of Isaiah 5 demonstrates how such a hermeneutic provides fresh insight into a well-worn text. Modern scholars have tended to see this passage as a chronological sequence of prophetic indictment (5:1-7), grievance (5:8-24), and military sentence (5:25-30); such interpretations typically exchange the chapter’s actual language for the sociopolitical realities that are thought to stand behind it, and moreover, cannot adequately account for the text’s redactional expansions. By contrast, an agrarian-rhetorical perspective on this passage identifies a theological sequence that communicates to the reader a paradigmatic vision of land-destruction and loss.
The Risk of Retelling: Gomer-bat-Diblaim, Biblical Retrieval, and the Male Gaze in The Prophet’s Wife
Authors: Gravett Emily O. 
Published: August 2019

AbstractMilton Steinberg’s posthumously published novel The Prophet’s Wife retells the story of the prophet Hosea and his “wife of whoredom,” Gomer. To analyze the novel’s interpretation of the biblical text, the article first reviews the book of Hosea and outlines the concept of “retrieval” in biblical retellings (that is, the restoration of characters overlooked in the Bible). Because Steinberg retrieves Gomer by drawing upon language of sight, body, and beauty, the article turns to the concept of the “male gaze” from film studies. Using this concept, the article examines several key moments of retrieval from the novel, in which Gomer is framed as a beautiful object for male eyes to appraise. What becomes clear is that Gomer’s retrieval in The Prophet’s Wife paradoxically results in her increased exposure to the male gaze. The article culminates in an exploration of this risk, possibly inherent in biblical retellings that retrieve female figures.
Affective Soundscapes in Thucydidean Battle Narrative
Authors: Hald Bradley 
Published: August 2019

Abstract
Thucydides’ History is deeply committed to the conventional correlation in Greek thought between sight and knowledge. In the Methodology chapters (1.20-3), the histo- rian grounds his investigative project in visual metaphor: it is a work that has been construc- ted ‘out of the most manifest evidence’, which promises to reveal the ‘least visible’ but ‘truest cause’ of this war. In contrast, Thucydides is suspicious of the epistemological value of hearing, repeatedly denigrating the ‘alluring’ sounds of poetic and hearsay accounts of Greek history. In this paper, I argue that this critique extends also to other sounds in the History, and that Thucydides’ anxieties over audition are directly related to the prob- lematic relation he sees between sound, knowledge, and emotion. While visual perception provides the normative pathway to cognitive evaluation and rational emotional response, sounds have the capacity to short-circuit the evaluative process by circumventing cognition and eliciting unmediated affective responses in hearing subjects.
Martem Accendere Cantu: The Meaning of Music on the Battlefield
Authors: Klavan Spencer A. 
Published: August 2019

Abstract
This paper examines in detail an under-appreciated passage from Philodemus of Gadara’s On Music in order to elucidate several important controversies in Hellenistic musical philosophy. The Stoic Diogenes of Babylon claimed that the emotional impact of trumpet tunes can inspire soldiers to fight. But the Epicurean Philodemus believed that the meaningful words (λόγοι) which stimulate our actions are utterly distinct from meaningless musical sound (µουσική). Philodemus therefore framed an alternative theory in which trumpet calls on the battlefield function not as music but as a kind of makeshift language, using conventional signifiers to communicate instructions. I show how both philosophers’ views arise logically out of doctrines from their respective schools. I then argue that the trumpet’s dual status as both performance instrument and communications device makes it a natural philosophical flashpoint: it raises central questions about what music is, how it affects listeners, and whether it can convey meaning.
Sounds of War: What Brought the Walls of Jericho Down?
Authors: Kramarz Andreas 
Published: August 2019

Abstract
The destruction of Jericho’s city walls (Joshua 6) is commonly attributed to the blowing of trumpets. After examining similar stories from ancient Greece, the article addresses various imprecisions of this notion. First, the Hebrew, Greek, and Latin versions of the biblical text suggest several possible instruments, but eventually the ram horn (shofar) remains the only reasonable option. Secondly, regarding the actual cause of the walls’ fall, textual analysis, again across languages, reveals a rather complex picture. Further insights are gained from the interpretations of both Jewish and early Christian commentators and contemporary scholarship. After considering a variety of possibilities, ranging from an earthquake to the ‘magic’ number seven, the solution proposed here is rooted in the soteriological hermeneutics of Sacred Scripture as a whole. In a way, none and all of the people’s actions are relevant, because only faith and obedience to God’s commandment elicit the divine ratification of salvation.
Λελεγίζω: An Obscure Verb
Authors: Panegyres Konstantine 
Published: August 2019

Abstract
The rare verb λελεγίζω is glossed as τὸ κιθαρίζω by Byzantine lexicographers. This paper discusses the form and meaning of λελεγίζω from the perspective of musical terminology, such as its relation to the verbs λαλέω and λαλαγέω or to -ίζω verbs derived from ethnic names. I propose that the most likely interpretation of λελεγίζω is that it means ‘to play the kithara in the Lelegian manner’.
New Voices in Ancient Music
Authors: Klavan Spencer A. , Lloyd James , Morgan Harry 
Published: August 2019

Abstract
This report provides a conspectus of the nine papers presented at ‘The Graduate Workshop in Ancient Greek and Roman Music’, held at the University of Oxford in June 2018. The workshop was organised with the intent of showcasing the innovative work of postgraduates in the field of ancient Greek and Roman music. Based around the themes of theory and practice, drama, and ritual, the papers reflect current areas of focus within the field and suggest promising avenues for further enquiry.
Sounds on Stage: Musical and Vocal Languages and Experiences
Authors: Arpaia Maria 
Published: August 2019

Abstract
The twenty-four papers delivered at the graduate conference entitled “Sounds on Stage: Musical and Vocal Languages and Experiences” (L’Aquila, 14-16 November 2018) investigated the relationship between music and theatrical performances from a comparative perspective. The presentations dealt with the role of music in several theatrical genres from different cultures and times: ancient Greek drama, musical theater (especially opera), modern and contemporary theater and ancient ritual Sanskrit drama.
Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis
Authors: Blanco Francisco J. , Camacho-Encina María , González-Rodríguez Lucía , Rego-Pérez Ignacio , Mateos Jesús , Fernández-Puente Patricia , Lourido Lucía , Rocha Beatriz , Picchi Florencia , Silva-Díaz María T. , Herrero Marta , Martínez Helena , Verges Josep , Ruiz-Romero Cristina , Calamia Valentina 
Published: August 2019

Background: In the present study, we explored potential protein biomarkers useful to predict the therapeutic response of knee osteoarthritis (KOA) patients treated with pharmaceutical grade Chondroitin sulfate/Glucosamine hydrochloride (CS+GH; Droglican, Bioiberica), in order to optimize therapeutic outcomes. Methods: A shotgun proteomic analysis by iTRAQ labelling and liquid chromatography–mass spectrometry (LC-MS/MS) was performed using sera from 40 patients enrolled in the Multicentre Osteoarthritis interVEntion trial with Sysadoa (MOVES). The panel of proteins potentially useful to predict KOA patient’s response was clinically validated in the whole MOVES cohort at baseline ( n = 506) using commercially available enzyme-linked immunosorbent assays kits. Logistic regression models and receiver-operating-characteristics (ROC) curves were used to analyze the contribution of these proteins to our prediction models of symptomatic drug response in KOA. Results: In the discovery phase of the study, a panel of six putative predictive biomarkers of response to CS+GH (APOA2, APOA4, APOH, ITIH1, C4BPa and ORM2) were identified by shotgun proteomics. Data are available via ProteomeXchange with identifier PXD012444. In the verification phase, the panel was verified in a larger set of KOA patients ( n = 262). Finally, ITIH1 and ORM2 were qualified by a blind test in the whole MOVES cohort at baseline. The combination of these biomarkers with clinical variables predict the patients’ response to CS+GH with a specificity of 79.5% and a sensitivity of 77.1%. Conclusions: Combining clinical and analytical parameters, we identified one biomarker that could accurately predict KOA patients’ response to CS+GH treatment. Its use would allow an increase in response rates and safety for the patients suffering KOA.
Management of a Persistent Cystic Duct Stump Leak Following Cholecystectomy With Percutaneous Transabdominal Cystic Duct Stump Embolization
Authors: Brown Craig S. , Sanogo Mamadou , Patel Arpan , Schulman Allison R. , Raghavendran Krishnan , Georgoff Patrick E. 
Published: August 2019

ABSTRACT
Cystic duct stump leak remains a difficult clinical problem despite advancements in endoscopic techniques. When these minimally invasive strategies fail, patients are often subject to high morbidity and mortality associated with open surgical exploration. We report the successful treatment of persistent biliary leak from the cystic duct stump following cholecystectomy using percutaneous transabdominal access of the cystic duct and coil embolization.
Acquired Hemophagocytic Lymphohistiocytosis Associated With Disseminated Herpes Simplex Virus in Immunocompetent Host
Authors: Schwartz Michael , O'Brien Courtney , Raya Nischal , Reau Nancy 
Published: August 2019

ABSTRACT
We report the case of an immunocompetent young woman who developed multisystem organ failure following herpes simplex virus type 2 and hemophagocytic lymphohistiocytosis. Despite intravenous acyclovir and supportive measures, she rapidly progressed to acute liver failure and died before she could receive orthotopic liver transplant.
Submucosal Fecalith Presenting as a Submucosal Cecal Mass
Authors: Prado Bustamante Jose , Benites Goñi Harold Eduardo , Palacios Salas Fernando , Dávalos Moscol Milagros 
Published: August 2019

ABSTRACT
A wide variety of benign and malignant submucosal lesions may arise from the wall of the large intestine. They can originate in the submucosa or in the muscular propia; furthermore, they can be caused by compression of extrinsic structures.
1,2
We report a case of a submucosal mass identified as a fecalith protruding into the cecum.
Idiosyncratic Liver Injury Due to Levocetirizine
Authors: Annunziata Giuseppe , Mayuko Imai , Barbara Mary 
Published: August 2019

ABSTRACT
Levocetirizine is an over-the-counter nonsedating antihistaminic agent commonly used to treat allergic diseases. Clinically significant acute liver injury has been very rarely associated with its use. Only 2 cases of acute liver injury associated with levocetirizine have been reported in the literature. We describe the case of a 67-year-old man who developed clinically significant acute hepatic injury after using levocetirizine. On the liver biopsy, there were histological findings of periportal inflammation and prominent cholestatic injury; such findings are consistent with those previously described in another similar case.
EVALUASI KINERJA INSTALASI PENGOLAHAN AIR MINUM (IPAM) KARANGPILANG I PDAM SURYA SEMBADA KOTA SURABAYA SECARA KUANTITATIF
Authors: Bhaskoro R. Gagak Eko , Ramadhan Tutut Eko 
Published: August 2019

IPAM Karangpilang I merupakan salah satu instalasi pengolahan air yang di miliki PDAM Kota Surabaya yang melayani kebutuhan air bersih di Kota Surabaya dengan kapasitas 1.450 L/det. Supaya IPAM tetap dapat beroperasi secara optimal, maka diperlukan evaluasi terhadap IPAM ini. Penelitian bertujuan untuk : 1) Mengukur kinerja tiap-tiap unit Instalasi Pengolahan Air Minum (IPAM) Karangpilang I Kota Surabaya; 2) Membandingkan kualitas air produksi yang dihasilkan oleh IPAM Karangpilang I dengan standar PERMENKES No.492 2010; 3) Menganalisa hasil evaluasi IPAM Karangpilang I. Evaluasi IPAM dilakukan dengan observasi, wawancara, studi literatur, praktik lapangan. Hasil yang diperoleh dari penelitian ini adalah Kinerja setiap unit operasi belum berjalan secara optimal, yaitu pada unit Koagulasi, Sedimentasi, Filtrasi. Kualitas air produksi IPAM Karangpilang I sesuai dengan dengan Permenkes No 492 tahun 2010 tentang Kualitas Air. Berdasarkan hasil evaluasi secara keseluruhan instalasi IPAM Karangpilang I pada saat eksisting sudah dapat mengolah air dengan baik sehingga air yang diolah dapat memenuhi baku mutu air.
MASTERPLAN SISTEM PENGELOLAAN AIR LIMBAH DOMESTIK DI WILAYAH PERKOTAAN KABUPATEN SUKOHARJO
Authors: Oktiawan Wiharyanto , Hardyanti Nurandani , Damayanti Poerborini 
Published: August 2019

Di Indonesia, air limbah domestik merupakan pencemar terbesar yang masuk ke badan air.Pemantauan dan pengendalian air buangan dapat dilakukan salah satunya denganmeningkatkan pelayanan dalam hal sanitasi. Pemerintah menetapkan target terhadap tahun2015-2019 antara lain 100% capaian pelayanan akses air minum, 0% proporsi rumah tanggayang menempati hunian dan permukiman tidak layak (kumuh) di kawasan perkotaan dan 100%capaian pelayanan akses sanitasi. Perencanaan masterplan ini bertujuan untuk menyediakanfasilitas sanitasi yang memadai dalam pengelolaan air limbah domestik terutama di wilayahperkotaan Kabupaten Sukoharjo. Masterplan ini akan mengkaji aspek teknis-teknologis dalamperencanaan pengelolaan air limbah domestik. Pada masterplan ini direncanakan akandibangun 3 buah IPAL skala perkotaan dan 8 buah IPAL skala permukiman besar yang akanmelayani 20% penduduk perkotaan Kabupaten Sukoharjo. IPAL skala perkotaan direncanakanterdapat 2 buah di Kecamatan Grogol dan 1 buah di Kecamatan Kartasura. IPAL skalapermukiman besar direncanakan terletak di Kecamatan Kartasura, Kecamatan Gatak, 2 buah diKecamatan Baki, masing-masing 1 buah di Kecamatan Bendosari, Gatak, Polokarto danKecamatan Sukoharjo. Selain itu, untuk pelayanan sistem setempat direncanakan 3 (tiga)daerah pelayanan IPLT yang dibangun secara bertahap. Tahap pertama yaitu optimalisasi IPLTEksisting (IPLT Mojorejo), tahap kedua yaitu pembangunan IPLT di Desa Bekonang KecamatanMojolaban, dan tahap ketiga pembangunan IPLT di Desa Grajegan Kecamatan Tawangsari.IPLT direncanakan dapat melayani sekitar 70% penduduk perkotaan.
The new Directive on Contracts for the Supply of Digital Content and Digital Services – Scope of Application and Trader’s Obligation to Supply – Part 1
Authors: Sein Karin , Spindler Gerald 
Published: August 2019

Abstract
After more than 3 years of discussions and negotiations the new contract law package consisting of the directive on the contracts for the supply of digital content and digital services and the new consumer sales directive have been finally adopted. The initial object-based regulatory approach has been kept, whereas the object of the contract now also encompasses digital services. The contract typology is still left within the discretion of the Member States and also the innovative concept of data as counter-performance is kept in the final version. The article discusses the scope of the digital content directive, including the complicated regulation on ancillary digital services (‘goods with digital elements’) as well as the trader’s main obligation – the obligation to supply. Conformity criteria, including the updating obligation, consumer’s remedies, trader’s liability as well as his right to make modifications will be dealt with in the follow-up article to be published in the next issue.
Carrying the Choice Theory of Contracts Further: Transfers, Welfare, and the Size of the Community
Authors: Esposito Fabrizio 
Published: August 2019

Abstract

The Choice Theory of Contracts is an ambitious, concise, and largely successful contribution to contract theory. Choice Theory is a liberal theory of contract law, grounded in a rich notion of autonomy, which stresses the obligation of the legal system to enhance our autonomy by ensuring the multiplicity of contractual types within the spheres of family, employment, home, and commerce.This article mitigates three shortcomings in The Choice Theory of Contracts and tries to carry Choice Theory further. A first shortcoming of the book is that the critique of transfer theory fails to acknowledge its analytical value. Second, in Part II of the book, Dagan and Heller overlap two issues: what the goods of contract are, and the compatibility of Choice Theory with the key concepts used by mainstream contract theories. Finally, Dagan and Heller do not fully acknowledge that the value of our autonomy is related to our ability to choose well. These revisions are useful to channelling scholarly attention on the implementation of Choice Theory and to sharpening the conceptual tools needed to do so.To show the potential of Choice Theory, this article carries it further. First, the economic concept of consumer sovereignty extends the programme of autonomy-grounded economic theories of contracts. Second, the size of the communities in which contractual relationships are created helps understand how various doctrines and even entire branches of the law foster the autonomy-enhancing capacity of contracts.The article concludes with a series of suggestions for carrying Choice Theory even further.
Stability and Hopf bifurcation periodic orbits in delay coupled Lotka-Volterra ring system
Authors: Su Rina , Zhang Chunrui 
Published: August 2019

AbstractIn this paper, we consider a class of delay coupled Lotka-Volterra ring systems. Based on the symmetric bifurcation theory of delay differential equations and representation theory of standard dihedral groups, properties of phase locked periodic solutions are given. Moreover, the direction and the stability of the Hopf bifurcation periodic orbits are obtained by using normal form and center manifold theory. Finally, the research results are verified by numerical simulation.
Toxicity of arsenic on isolated human lymphocytes: The key role of cytokines and intracellular calcium enhancement in arsenic-induced cell death
Authors: Zarei Mohammad Hadi , Pourahmad Jalal , Nassireslami Ehsan 
Published: August 2019

Abstract
Arsenic (As) is a semi-metal which causes health problems in human, and immune system has been documented as one of the main target of arsenic toxicity. Apoptosis has a crucial role in regulation of immune system, but it can also have an important role in As immune suppression. So, we decided to assess the comprehensive mechanism of As cytotoxic effect on lymphocytes isolated from human blood. We determine the direct effect of arsenic on human lymphocytes which have a key role in immune system functionality. To evaluate the mechanism of arsenic toxicity on human lymphocytes, we use accelerated cytotoxicity mechanisms screening (ACMS) technique. Lymphocytes were isolated from blood of healthy persons using Ficoll-paque PLUS standard method. Following treatment of human lymphocytes with 0.05-50 μM of arsenic for 12 h, cell viability was measured. For determination of mechanistic parameters, isolated human lymphocytes incubated with 1/2IC5012h (7.5 μM), IC5012h (15 μM) and 2IC5012h (30 μM) for 2, 4 and 6 h. The results of this study demonstrate arsenic-associated apoptosis in human lymphocytes is mainly through enhancement of intracellular calcium which causes oxidative stress and following adverse effect on lymphocytes organelles (like mitochondria and lysosome). Involvement of cellular proteolysis, activation of caspase-3, lipid peroxidation and stimulation of cytokines (IL2, INF-gamma and TNF-alpha) production were also associated with arsenic induced lymphocyte toxicity.