bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of an exercise intervention on maternal depression, anxiety, and fatigue: a systematic review and meta-analysis
Authors: Yu Haoran , Mu Qinglei , Lv Xunjin , Chen Shuainan , He Hao 
Published: November 2024

BackgroundExisting meta-analyses suggest that exercise intervention may play a crucial therapeutic role in improving maternal depression, anxiety and fatigue symptoms. However, the efficacy varies across different exercise content, duration, frequency, cycle, intensity, format and intervention period.ObjectiveUsing meta-analysis to propose the best intervention program and examine the effect of exercise intervention on maternal depression, anxiety, and fatigue.MethodsFive databases (PubMed, Web of Science, Embase, Cochrane Library, CNKI) were searched from inception to June 2024, a total of 37 literatures were included. The methodological quality of the included literatures was assessed using the Cochrane Risk of Bias tool and the PEDro scale. When heterogeneity was high, we used random-effects models. Funnel plots were used to assess publication bias. Sensitivity analysis was used to verify the robustness of the combined results. Subgroup analysis was used to explore sources of heterogeneity.ResultsExercise has beneficial effects on the improvement of maternal depression [g = −0.71, 95%CI (−0.93, −0.49), p = 0.00], anxiety [g = −1.09, 95%CI (−1.42, −0.76), p = 0.00] and fatigue [g = −0.64, 95%CI (−0.88, −0.40), p = 0.00] symptoms. Postnatal interventions may be more effective than prenatal. Low-moderate intensity yoga with group + individual, 4–5 times/week, 40–60 min/time, duration 4–8 weeks is most effective in improving depressive symptoms. Low-intensity yoga with group + individual, 4–5 times/week, 40–60 min/time, duration 4–8 weeks is most effective for improving anxiety symptoms. Low-intensity Pilates with group, 1–2 times/week, 40–60 min/time, duration 4–8 weeks is most effective for improving fatigue symptoms.ConclusionThis meta-analysis demonstrates the positive effect of exercise on improving maternal depression, anxiety and fatigue and suggests the best intervention program. Maternal perceptions that postpartum exercise is safer may account for the better outcomes of postpartum intervention. Further higher quality and large-scale trials are needed to substantiate our findings.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, CRD42024567987.
Relationships between dyadic coping, marital adjustment, and post-traumatic growth in patients with maintenance hemodialysis patients and their spouses
Authors: Zhang Qi , Cao Heng 
Published: November 2024

AimTo measure the relationships between dyadic coping, marital adjustment, and post-traumatic growth in patients with maintenance hemodialysis and their spouses.BackgroundPost-traumatic growth is common in patients facing maintenance hemodialysis. However, studies tend to focus on these patients as individuals rather than as part of a couple. Dyadic coping in a couple is important for their marital adjustment; however, little is known about how a couple's dyadic coping influences their marital adjustment and impacts their posttraumatic growth.DesignCross-sectional study.MethodsA questionnaire survey was conducted among patients receiving maintenance hemodialysis and their spouses. Patients were recruited between December 2021 and October 2022 using convenience sampling from the blood purification centers of two first-class tertiary hospitals. A total of 230 couples (460 individuals) of patients receiving maintenance hemodialysis and their spouses were enrolled. A general condition questionnaire, the dyadic coping scale, and the Locke-Wallace marital adjustment scale were used for assessments and data entry and analysis were performed using EpiData 3.1, SPSS 25.0, and Mplus 8.4.ResultsThe dyadic coping of patients receiving maintenance hemodialysis was positively correlated with both marital adjustment and posttraumatic growth, as was the dyadic coping of their spouses. The marital adjustment of both patients and their spouses was found to partially mediate the association between dyadic coping and posttraumatic growth.ConclusionSubject-mediated effects between the levels of dyadic coping, marital adjustment, and posttraumatic growth were established for both patients receiving maintenance hemodialysis and their spouses, and it was found that the marital adjustment in both showed varying degrees of mediation in the relationship between their dyadic coping and posttraumatic growth.ImpactThe findings of the study suggest that attention should be given to promoting dyadic coping behaviors in patients receiving maintenance hemodialysis and their spouses. It is recommended that nurses offer both education and support to couples to promote dyadic coping.
Exploring factors influencing the quality of life in diabetes: a network analysis-based study
Authors: Chen Lu , Li Ling , Qiao Kexin , Qiao Zhengxue , Xiang Ying , Zhou Jiawei , Bu Tianyi , Hu Xiaomeng , Ke Siyuan , Kan Yuecui , Liu Xuan , Ji Yanping , Qiu Xiaohui , Yang Yanjie 
Published: November 2024

ObjectiveThe purpose of this study was to explore the key pathways leading to low quality of life in type 2 diabetes patients by means of network analysis, so as to provide the possibility of effective interventions.MethodsThe study involved 1,011 adult type 2 diabetes patients from a tertiary hospital in Harbin. Data was collected through questionnaires, and network analysis was performed using R software to assess the centrality and predictability of each node.Results“Depression” and “Submission” (weight = 0.26), “Depression” and “Physiological field” (weight = -0.16), exhibit the strongest associations. Overall, “Depression” has the highest weight in the association with diabetes symptom, regarding betweenness, “Depression” and “Submission” exhibit the highest scores, Furthermore, the analysis of closeness centrality reveals that “Depression” and “Submission” share the highest level of proximity, it suggests that they have the shortest distances to other network factors in our research network.ConclusionDepression and Submission are likely to be key factors affecting the quality of life of people with diabetes. Providing psychological support and scientific coping strategies for diabetes patients may be an effective way to help them live a better life.
Association between the American Heart Association’s New Life’s Essential 8 Metrics and Depression Symptom in U.S General Adults, Finding from NHANES 2005-2018
Authors: Ruan Zhuoer , Zhu Jie , Xu Shengnan , Liang Jinghong , Shi Shengqiao 
Published: November 2024

BackgroundThe American Heart Association (AHA) recently introduced a new metric for promoting cardiovascular health (CVH) called Life’s Essential 8 (LE8). However, there has been no investigation into the relationship between levels of LE8 and the risk of depression symptom. Therefore, our objective was to determine this association using a nationally representative sample of U.S adults.MethodsUtilizing cross-sectional data from the NHANES spanning the years 2005 to 2018, we computed scores for both overall CVH and individual LE8 components. The survey-weighted logistic regression models were conducted to determine whether LE8 was associated with depression symptom.ResultsA total of 25,357 adults aged 20 and above were included in the study, representing a population of 1,184 million non-institutionalized U.S residents. The study revealed that individuals with positive scores in both individual and total LE8 metrics were less likely to experience depressive symptoms compared to those with negative scores. Furthermore, a significant negative linear trend was observed, showing that as the overall number of favorable LE8 scores increased, the likelihood of depressive symptoms decreased.ConclusionAttaining a higher CVH score, as defined by the LE8, is strongly linked to a lower risk of experiencing depressive symptoms in adult residents of the U.S.
COVID-19 vaccination survey and anti-SARS-CoV-2 IgG responses in a human cohort from Schistosoma mansoni-endemic villages in Mayuge District, Uganda: a cross-sectional study
Authors: Niu Mimi , Mu Yi , Adriko Moses , Candia Rowel , Jones Malcolm K. , McManus Donald P. , Egwang Thomas G. , Cai Pengfei 
Published: November 2024

IntroductionThe coronavirus disease 2019 (COVID-19) pandemic has resulted in devastating health and economic consequences worldwide. Vaccination has been a central pillar for COVID-19 prevention and control. Understanding the immunomodulatory effects of helminth infections on COVID-19 vaccine-induced immune responses and vaccine efficacy is crucial to the development and deployment of effective vaccination strategies in low- and middle-income countries with a high prevalence of worms.MethodsIn September 2022, we conducted a cross-sectional, population-based survey in five Schistosoma mansoni endemic villages in Mayuge District, Uganda (n = 450). The prevalence of schistosomiasis and soil-transmitted helminths was determined by the Kato-Katz (KK) technique on two stool samples collected from each participant. A subset of individuals (n = 204) were interviewed in a COVID-19 vaccination survey. IgG levels against the SARS-CoV-2 spike S1 subunit (anti-S1 IgG) were measured by enzyme-linked immunosorbent assay (ELISA) in collected serum samples.ResultsThe overall schistosomiasis and hookworm prevalence rates in the five villages were 36.4% (166/450) and 36.9% (168/450), respectively. Within the cohort, 69.78% (314/450) of the subjects had a positive anti-S1 IgG response. COVID-19 vaccination coverage among the interviewed participants was 93.14% (190/204; 95% CI, 88.8% − 95.9%). However, 81% (154/190) of COVID-19 vaccinees had an anti-S1 IgG titre ≤200. In an adolescent group receiving a single dose of the BNT162b2 mRNA vaccine (n = 23), an inverse correlation was observed between anti-S1 IgG antibody level/titre and faecal egg count. Within the above group, anti-S1 IgG levels/titres were significantly lower in subjects with moderate or heavy S. mansoni infection (n = 5) than those in KK-negative individuals (n = 9).ConclusionAlthough the acceptance rate of COVID-19 vaccination was high, the majority of participants received only a single vaccine dose and the overall anti-S1 IgG titres in confirmed vaccinees were low. Moderate-to-heavy schistosome infections blunted the antibody responses following vaccination with a single dose of BNT162b2. These observations confirm the necessity for a second COVID-19 vaccine dose for two-dose primary immunization series and call for implementation research that may inform the development of a ‘treat and vaccinate’ policy during vaccination roll-out in regions with heavy worm burdens.
Development and validation of the Integrative Vitality Scale
Authors: Yoon Seok In , Park Hui Yeong , Chung Sun Yong , Kim Jong Woo 
Published: November 2024

IntroductionVitality is a construct based on traditional vitalism, and is a concept similar to energy (Qi), passion, and motivation as the essential power possessed by organisms. Recently, various methods and tools have been designed to evaluate vitality as a health indicator. This study aimed to develop and validate an Integrative Vitality Scale (IVS) based on traditional Eastern medicine and modern psychology.MethodsWe conducted two online surveys and one pre-post comparison with Korean adults. Descriptive statistics and factor analysis were performed for scale development, and correlation and regression analysis were performed for validation.ResultsExploratory (n = 348) and confirmatory (n = 349) factor analyses showed that two subfactors (physical and psychological vitality) best represented integrative vitality. The IVS-total and subscales had good internal consistency (α = 0.89–.094) and test-retest reliability (r = 0.71–0.80). Ten health-related experts (e.g., doctors, clinical psychologists, and counselors) evaluated the IVS as having excellent content validity. The IVS-total and subscales had a high correlation with existing vitality-related scales but a low correlation with pathological symptoms such as hypomania, suggesting convergent and discriminant validity. The IVS-total and subscales were negatively correlated with depression and fatigue but positively correlated with well-being and quality of life, suggesting criterion validity. The IVS had additional predictive power for depression, fatigue, and well-being even after controlling for existing vitality-related scales, suggesting incremental validity. Finally, after 16 weeks of mindfulness training (n = 28), IVS-total and subscales significantly increased.DiscussionThese findings suggested that the IVS is a valid and reliable tool for assessing physical and psychological vitality. Furthermore, the IVS could be used as a clinical indicator to predict symptoms related to low energy, such as depression and fatigue, and as an indicator of sustainable well-being.
Impact of visual impairments on cognitive functions in older adults: insights from NHANES data
Authors: Fu Xiangxiang , Du Zhenni , Ying Jianing , Zhu Qianwei 
Published: November 2024

BackgroundVisual impairments (VI) are common in the older adults and may affect cognitive functions through mechanisms such as reduced sensory input and increased social isolation. Although current understanding of this association is incomplete, evidence suggests a potential link between poor vision and cognitive decline. This study aims to investigate the relationship between Subjective Visual Impairment (SVI), Objective Visual Impairment (OVI), and cognitive decline in the older adults, and assess whether these associations remain significant after controlling for multiple confounding factors.MethodsData from the National Health and Nutrition Examination Survey (NHANES) for the years 1999–2002 were utilized, focusing on participants aged 60 and above. A total of 2,522 eligible participants were analyzed to assess their cognitive function and visual status. Weighted logistic regression models were used to explore the relationship between cognitive status and VI, progressively adjusting for confounding variables. Non-linear associations between cognitive score and VI were further explored using restricted cubic spline analysis.ResultsVisual impairments were significantly associated with worse cognitive function. Participants with SVI had a 3.437-fold higher risk of cognitive decline compared to those without SVI (95% CI: 2.648–4.461, p &lt; 0.001). After adjusting for multiple covariates, the association remained significant (adjusted OR for SVI: 1.921, 95% CI: 1.346–2.742, p = 0.001; adjusted OR for OVI: 3.075, 95% CI: 1.740–5.433, p = 0.001). The restricted cubic spline analysis revealed a non-linear relationship between cognitive score and visual impairment, suggesting that the impact of visual impairment on cognitive decline varies across different levels of cognitive function.ConclusionThis study highlights a significant association between visual impairment and cognitive decline, even after controlling for multiple potential influencers. The findings support the integration of vision assessments into older adults care to identify and address vision problems early, potentially mitigating cognitive decline. The discovery of non-linear relationships further suggests that vision interventions may be particularly vital at certain stages of cognitive scores.
Longitudinal analysis of insulin resistance and sarcopenic obesity in Chinese middle-aged and older adults: evidence from CHARLS
Authors: Xu Chunyan , He Ling , Tu Yansong , Guo Canhui , Lai Hurong , Liao Caifeng , Lin Chuyang , Tu Huaijun 
Published: November 2024

ObjectiveThe correlation between surrogate insulin resistance (IR) indices and sarcopenic obesity (SO) remains uncertain. This study aimed to assess the association between six IR surrogates—triglyceride-glucose (TyG), TyG-waist circumference (TyG-WC), TyG-waist-to-height ratio (TyG-WHtR), triglyceride-to-high-density lipoprotein-cholesterol ratio (TG/HDL), metabolic score for insulin resistance (METS-IR), and Chinese visceral adiposity index (CVAI)—and SO risk in a middle-aged and older population in China.MethodsThe study employed longitudinal data obtained from the China Health and Retirement Longitudinal Study (CHARLS) between 2011 and 2015, involving 6,395 participants. We used multivariate logistic regression models to examine the link between six surrogates and SO. Nonlinear relationships were evaluated using restricted cubic spline analysis, and subgroup analyses were conducted for validation. Receiver operating characteristic (ROC) curves were used to assess predictive capabilities.ResultsOver the course of a 4-year follow-up period, 319 participants (5.0%) developed SO. In the fully adjusted model, all six surrogates were significantly associated with SO. The adjusted odds ratios (ORs) with a 95% confidence interval (95% CI) per standard deviation increase were 1.21 (1.08–1.36) for TyG, 1.56 (1.39–1.75) for TyG-WC, 2.04 (1.81–2.31) for TyG-WHtR, 1.11 (1.01–1.21) for TG/HDL, 1.67 (1.50–1.87) for METS-IR, and 1.74 (1.55–1.97) for CVAI. Notably, TyG-WC, TyG-WHtR, TG/HDL, METS-IR, and CVAI exhibited nonlinear correlations with SO. Conversely, TG/HDL did not exhibit a significant association during subgroup analysis. Furthermore, TyG-WHtR had a significantly larger area under the receiver operating characteristic curve than other indices.ConclusionThe results indicated that TyG, TyG-WC, TyG-WHtR, METS-IR, and CVAI were significantly and positively associated with SO incidence. Meanwhile, TyG-WC, TyG-WHtR, METS-IR, and CVAI showed nonlinear relationships with SO. Specifically, TyG-WHtR may be the most appropriate indicator for predicting SO among middle-aged and older Chinese adults.
Associations between modifiable risk factors and cognitive function in middle-aged and older Chinese adults: joint modelling of longitudinal and survival data
Authors: Ran Qin , Yang Fang , Su Qin , Li Peng , Hu Yaoyue 
Published: November 2024

BackgroundStronger associations between modifiable risk factors and cognitive function have been found in younger than older adults. This age pattern may be subject to mortality selection and non-ignorable missingness caused by dropouts due to death, but this remains unclear.MethodsLongitudinal data from 9,562 adults aged 50 and older from Waves 1–4 (2011–2018) of the China Health and Retirement Longitudinal Study were used. Cognitive function was assessed repeatedly using a battery of cognitive tests. Joint models of longitudinal and survival data were applied to examine the associations of modifiable risk factors with cognitive function and mortality.ResultsWorse cognitive function score was associated with being female (coefficient[β] = −1.669, 95% confidence interval [CI]: −1.830, −1.511, p &lt; 0.001), low education (β = −2.672, 95%CI: −2.813, −2.530, p &lt; 0.001), rural residence (β = −1.204, 95%CI: −1.329, −1.074, p &lt; 0.001), stroke (β = −0.451, 95%CI: −0.857, −0.051, p = 0.030), probable depression (β = −1.084, 95%CI: −1.226, −0.941, p &lt; 0.001), and current smoking (β = −0.284, 95%CI: −0.437, −0.133, p &lt; 0.001); whereas dyslipidaemia (β = 0.415, 95% CI: 0.207, 0.626, p &lt; 0.001), heart disease (β = 0.513, 95% CI: 0.328, 0.698, p &lt; 0.001), overweight (β = 0.365, 95% CI: 0.224, 0.506, p &lt; 0.001) and obesity (β = 0.264, 95% CI: 0.048, 0.473, p = 0.014) were associated with better cognitive function. These associations changed less than 5% when the longitudinal and survival data were modelled separately. An increase in cognitive function over age was associated with reduced mortality risk (hazard ratio: 0.418, 95%CI: 0.333, 0.537, p &lt; 0.001). The association between socioeconomic disadvantage and cognitive function was more evident in women than in men, while the associations of socioeconomic disadvantage and lifestyle with cognitive function increased with age.ConclusionMortality selection and non-ignorable missingness caused by dropouts due to death played a minor role in the associations between modifiable risk factors and cognitive function in middle-aged and older Chinese adults.
Does physical activity affect social skills and antisocial behavior? The gender and only child status differences
Authors: Yang Yuke , Gao Yan , Yi Xiangren , Hu Yining , Zhao Liangyu , Chen Lu , Sui Wenze , Zhang Shuoqin , Ma Sen 
Published: November 2024

BackgroundThis study aims to explore the effects of physical activity on adolescents' social skills and antisocial behavior, as well as gender and only child status differences among Chinese adolescents.MethodsWe used longitudinal data, collecting baseline data for 2021–2022 and follow-up in 2022–2023. A total of 3,206 students were enrolled, including 1,510 males (Age ± SE: 13.62 ± 1.69) and 1,696 females (Age ± SE: 14.09 ± 1.85), 1,339 only children (Age ± SE: 13.76 ± 1.95), and 1,867 non-only children (Age ± SE: 13.95 ± 1.66). The fixed effects model was used to identify the effects of different types of physical activity on adolescent social behavior and the heterogeneity analysis.Results(1) We found that skipping rope (β = 2.284, t = 5.76), walking (β = 3.495, t = 9.53), cycling (β = 1.271, t = 3.21), jogging (β = 2.614, t = 5.92), and badminton (β = 1.409, t = 2.96) had a positive impact on adolescents' social skills. Tag games (β = −1.615, t = −3.83), swimming (β = −2.862, t = −4.42), dancing (β = −1.11, t = −2.29), and skiing (β = −2.771, t = −3.27) had a negative impact on adolescents' social skills. Skipping rope (β = −1.596, t = −5.86), walking (β = −1.814, t = −7.44), cycling (β = −1.066, t = −4.07), and jogging (β = −1.617, t = −5.30) tended to reduce adolescents' antisocial behavior. Tag games (β = 1.685, t = 5.54), swimming (β = 0.947, t = 2.06), ice skating (β = 1.772, t = 2.71), and skiing (β = 1.468, t = 2.31) tended to increase adolescents' antisocial behavior. In addition, we found that these effects differ by gender and only child status. (2) Boys had significantly higher participation rates in activities. Only children had higher participation rates in skipping rope, baseball or softball, and volleyball, but non-only children had higher participation rates in walking, cycling, jogging, other aerobic exercises, and badminton. (3) Girls had higher social skills, but boys and only children had significantly higher rates of antisocial behavior.ConclusionOur results provide a novel understanding that can inform interventions and improvements in social behavior among Chinese adolescents. Stakeholders such as educators, policymakers, and health professionals can develop more tailored and effective strategies to promote positive social development among adolescents.