bluuebunny/crossref_metadata_2025_split huggingface dataset:
The acute effects of decaffeinated versus caffeinated coffee on reaction time, mood and skeletal muscle strength
Authors: Sane Rohit M. , Jadhav Pradeep R. , Subhedar Sanjana N. 
Published: August 2019

Abstract

Background
Caffeinated coffee, a psycho-stimulant, is widely consumed throughout the globe. However, its chronic consumption has deleterious effects on human health. Meanwhile, decaffeinated coffee has low content of caffeine and thus can be an alternative to caffeinated coffee. Therefore, the study was undertaken to explore and compare the acute effects of decaffeinated and caffeinated coffee on reaction time, mood and skeletal muscle strength in healthy volunteers.

Methods
This was a prospective, interventional, comparative type of study. The study included 70 healthy adults divided into two groups (Caffeinated coffee group and Decaffeinated coffee group). The following parameters were assessed: reaction time was assessed by digital display multiple-choice apparatus, mood by Visual Analogue Scale (VAS) and Profile of Mood States revised version (POMS) and skeletal muscle strength by hand dynamometer. All parameters in both groups were assessed pre-intervention (baseline) and 30 min post-intervention.

Results
In both groups (decaffeinated and caffeinated coffee) post-intervention, there was a statistically significant (p < 0.05) improvement in the reaction time (VRT) and mood (VAS, POMS) from the baseline. However, both groups did not show any significant effects on the skeletal muscle strength. Upon comparing the two groups, we found that caffeinated coffee showed higher and significant improvement of mood than decaffeinated coffee.

Conclusions
Decaffeinated coffee exerts an acute significant stimulatory effect on the reaction time and mood. However, these effects in comparison to caffeinated coffee are low. Further randomized control clinical trials are thus needed to validate these interesting findings.
IoT-Based Health Monitoring System Using BeagleBone Black with Optical Sensor
Authors: Saranya K. Durga , Krishnamurthy R. , Srinivas K. N. H. , Sarveswara Rao T. D. N. S. S. , Amiri I. S. 
Published: August 2019

AbstractThere is an increase in the number of chronic and heart diseases due to work culture etc. The current hospital-centric system is becoming inefficient to treat patients that demand immediate attention and this can efficiently be implemented by using the Internet of Things (IoT) technology. The aim of this paper is to implement IoT-based health monitoring system which measures temperature, blood pressure, and heartbeat of a patient located remotely and send the data to the doctor for analyzing the condition of the patient. And also an optical light sensor is used to check the light condition in the patient room and based on the sensor value the light will be controlled (ON/OFF). The system is implemented using a BeagleBone Black (BBB) development board. This model saves the work time of the doctors to check the patient’s condition. By using the Global System for Mobile communication (GSM), the patient’s data is sent to the cloud through which the doctor can monitor the parameters anywhere in the world using the mobile application or web page.
Polish, Silesian and Local Cloth Seals from Excavations in Gdańsk, Poland
Authors: Połczyński Łukasz , Przymorska-Sztuczka Magdalena 
Published: August 2019

AbstractThis article presents a collection of early modern cloth seals revealed during an excavation in Gdańsk (Poland). Our aim is to present a collection of an often-neglected category of artefacts. These are cloth seals from towns and villages located along the Polish-Lithuanian Commonwealth and Habsburg Monarchy border. Tracking the import of cloth to Gdańsk (the most important commercial centre on the Baltic Sea at that time) based on the analysis of the origin of textile seals is crucial as it allows us, in some sense, to reconstruct the cloth market of mid-seventeenth century Gdańsk.
Synthesis, electrical properties, and kinetic thermal analysis of polyaniline/ polyvinyl alcohol - magnetite nanocomposites film
Authors: AlFannakh Huda , Arafat S. S. , Ibrahim S. S. 
Published: August 2019

Abstract
Polyaniline-poly vinyl alcohol (PANI-PVA) conducting blends containing 15 wt% aniline were synthesized by in situ polymerization of aniline. Three-phase polymer blended nanocomposites with different contents of magnetite (5, 10 and 15 wt.%) were also synthesized. We measured the current-voltage (I-V) curves for the conducting blend and its magnetite nanocomposite. We also measured their thermal stability, and performed kinetic analysis through thermogravimetric analysis. We observed that the three phase nanocomposites showed enhanced electrical conductivity compared with that of the conductive blend, and no electrical hysteresis. The PVA/PANi blend was more stable above 350∘C and the addition of Fe3O4 enhanced the thermal stability of the conductive blend. The apparent activation energy of the three phase nanocomposites was greater than those of both the pure PVA and PVA/PANi samples. These results suggest that such three phase nanocomposites could be used in a range of applications.
Determining the Unsaturated Hydraulic Properties of Cohesionless Soils: An Integrated Experimental and Inverse Modeling Approach
Authors: El Mohtar C. S. , Sangroya-Kundu R. 
Published: August 2019

Abstract
A simple, inexpensive and quick method for measuring the van Genuchten soil water retention curve (SWRC) model parameters for cohesionless soil is presented. The proposed method is an integration of laboratory testing and numerical modeling. The experimental testing consists of multistage bottom-top water imbibition of a dry sand column while recording pore pressure at the inlet. The experiment is then simulated numerically using Hydrus 1D, and the van Genuchten SWRC model parameters are determined through inverse modeling to match the recorded pore pressures. The soil column flushing includes multiple flow stoppages and resumptions, all before permeating one pore volume of water. The flow stoppage results in a time-dependent redistribution of moisture near the waterfront that is controlled by the unsaturated hydraulic properties of the soil and is reflected by changes in the pore pressure measurements. The uniqueness of this method comes from the simple experimental setup and the multistage flushing that can reduce the testing time by a factor of 30 compared with other methods. The results from testing three different sands with different grain size distributions are presented. The new method generated consistent results from multiple specimens tested at a range of flow rates for the three sands. The hypothesis behind moisture redistribution during flow stoppage was confirmed through a combination of experimental and numerical observations. The van Genuchten SWRC parameters obtained from the new method were comparable to those obtained using the conventional hanging column test for Sands B and C and available data in the literature. Sand A could not be tested using the hanging column test because of its large particle size, which demonstrates the wide range of soils that can be tested using the new proposed method.
Visual Motion and Form Integration in the Behaving Ferret
Authors: Dunn-Weiss Erika , Nummela Samuel U. , Lempel Augusto A. , Law Jody M. , Ledley Johanna , Salvino Peter , Nielsen Kristina J. 
Published: August 2019

AbstractFerrets have become a standard animal model for the development of early visual stages. Less is known about higher-level vision in ferrets, both during development and in adulthood. Here, as a step towards establishing higher-level vision research in ferrets, we used behavioral experiments to test the motion and form integration capacity of adult ferrets. Motion integration was assessed by training ferrets to discriminate random dot kinematograms (RDK) based on their direction. Task difficulty was varied systematically by changing RDK coherence levels, which allowed the measurement of motion integration thresholds. Form integration was measured analogously by training ferrets to discriminate linear Glass patterns of varying coherence levels based on their orientation. In all experiments, ferrets proved to be good psychophysical subjects that performed tasks reliably. Crucially, the behavioral data showed clear evidence of perceptual motion and form integration. In the monkey, motion and form integration are usually associated with processes occurring in higher-level visual areas. In a second set of experiments, we therefore tested whether PSS, a higher-level motion area in the ferret, could similarly support motion integration behavior in this species. To this end, we measured responses of PSS neurons to RDK of different coherence levels. Indeed, neurometric functions for PSS were in good agreement with the behaviorally derived psychometric functions. In conclusion, our experiments demonstrate that ferrets are well suited for higher-level vision research.
Reduction in Length of Stay and Morphine Use for NAS With the “Eat, Sleep, Console” Method
Authors: Blount Thomas , Painter Alana , Freeman Emily , Grossman Matthew , Sutton Ashley G. 
Published: August 2019

OBJECTIVES:
To reduce average length of stay (ALOS) in infants with neonatal abstinence syndrome (NAS) transferred to the inpatient floor from the mother-infant unit. Secondarily, we aimed to reduce morphine exposure in these infants.

METHODS:
Using quality improvement methodology, we redesigned our approach to NAS on the inpatient floor. Key interventions included transitioning from a modified Finnegan Neonatal Abstinence Scoring System to the “Eat, Sleep, Console” method for withdrawal assessment, reeducation on nonpharmacologic interventions, and adding as-needed morphine as initial pharmacotherapy. Data for infants ≥35 weeks’ gestation with confirmed in utero opioid exposure and worsening symptoms of NAS requiring transfer to the inpatient floor were obtained, including ALOS, number of morphine doses, and total morphine amount administered. Infants with conditions requiring nothing by mouth for &gt;12 hours or morphine initiation in the ICU were excluded.

RESULTS:
ALOS for infants (baseline n = 40; intervention n = 36) with NAS transferred to the inpatient floor decreased from 10.3 to 4.9 days. Average morphine administered decreased from 38 to 0.3 doses per infant. No infant in the intervention period required scheduled morphine. The percent of all infants transferred to the floor for NAS requiring any morphine decreased from 92% at baseline to 19% postimplementation. There were no observed adverse events or NAS-related readmissions in the intervention period.

CONCLUSIONS:
Transitioning to the Eat, Sleep, Console assessment with re-enforcement of nonpharmacologic care and use of as-needed morphine as initial pharmacotherapy resulted in a notably decreased ALOS and near elimination of postnatal opioid treatment of infants with NAS managed on our inpatient floor.
Successful Implementation of the Eat Sleep Console Model of Care for Infants With NAS in a Community Hospital
Authors: Dodds Douglas , Koch Kayla , Buitrago-Mogollon Talia , Horstmann Sara 
Published: August 2019

BACKGROUND:Opioid use across the United States is increasing. The concomitant rise in the incidence of neonatal abstinence syndrome (NAS) has made care of infants with this disease process a top priority for pediatric centers across the country. There is growing evidence that the Eat Sleep Console (ESC) model of care is superior to the established Finnegan Neonatal Abstinence Scoring System model.OBJECTIVES:We aimed to improve the care of infants with NAS by transitioning from the Finnegan Neonatal Abstinence Scoring System model to the ESC model of care. Our goal was to decrease the average length of stay from 11.77 to 5.94 days without having an increase in readmissions.METHODS:A multidisciplinary team was created. Education about NAS and ESC was created and distributed. Patients were admitted to the inpatient unit, and outcomes were observed. Standard quality improvement methodology was used for this intervention.RESULTS:After implementation of the ESC care model, average length of stay decreased to 5.94 days, with 0 patients readmitted or transferred for NAS-related complications. We saw a 48% reduction in average variable cost per patient. In addition to these reductions and savings, total per patient morphine exposure was reduced from 2.25 to 0.45 mg/kg, a 79% reduction in use.CONCLUSIONS:The ESC model of care was successfully implemented at our institution with resultant cost savings, decreased length of stay, and decreased medication use. Our work further supports the adoption of this new model of care for infants with NAS.
Postpartum Nurses’ Experience Caring for Infants With Neonatal Abstinence Syndrome
Authors: Loyal Jaspreet , Nguyen Victoria N. , Picagli Doreen , Petrucelli Amy , O’Mara Elizabeth , Grossman Matthew R. , Colson Eve 
Published: August 2019

OBJECTIVES:In previous years, otherwise healthy infants with neonatal abstinence syndrome (NAS) in our hospital were transferred to the NICU and frequently treated with medication. Currently, infants with NAS room-in with their mothers and rarely require medication. We sought to understand the lived experience of nurses on maternity and well-newborn units caring for infants with NAS.METHODS:We conducted focus groups of registered nurses on postpartum units at 2 hospitals using qualitative methodology. Themes were identified through consensus, and the focus groups were stopped when no new themes were identified.RESULTS:Seventeen postpartum nurses participated in 5 focus groups. The following major themes emerged: (1) managing the expectations of parents of newborns with NAS, (2) current NAS protocol (positive aspects of rooming-in and challenges with withdrawal scoring tool), (3) inconsistencies in care and communication, (4) perceived increase in nursing workload on the postpartum unit, and (5) nurses’ emotional response to the care of infants with NAS.CONCLUSIONS:We highlight the perspectives of nursing staff on the well-newborn unit who were previously unaccustomed to caring for infants with NAS. With increasing numbers of infants with NAS and longer stays on the well-newborn unit, hospitals must prepare to better support staff and implement protocols that offer consistency in practice.
Patient Satisfaction and Antibiotic Prescribing for Respiratory Infections by Telemedicine
Authors: Foster Charles B. , Martinez Kathryn A. , Sabella Camille , Weaver Gregory P. , Rothberg Michael B. 
Published: August 2019

BACKGROUND AND OBJECTIVES:
Respiratory tract infections (RTIs) are a common reason for direct-to-consumer (DTC) telemedicine consultation. Antibiotic prescribing during video-only DTC telemedicine encounters was explored for pediatric RTIs.

METHODS:
Encounter data were obtained from a nationwide DTC telemedicine platform. Mixed-effects regression was used to assess variation in antibiotic receipt by patient and physician factors as well as the association between antibiotic receipt and visit length or patient satisfaction.

RESULTS:
Of 12 842 RTI encounters with 560 physicians, antibiotics were prescribed in 55%. The provider was more likely to receive a 5-star rating from the parent when an antibiotic was prescribed (93.4% vs 80.8%). A 5-star rating was associated with a prescription for an antibiotic (odds ratio [OR] 3.38; 95% confidence interval [CI] 2.84 to 4.02), an antiviral (OR 2.56; 95% CI 1.81 to 3.64), or a nonantibiotic (OR 1.93; 95% CI 1.58 to 2.36). Visit length was associated with higher odds of a 5-star rating only when no antibiotic was prescribed (OR 1.03 per 6 seconds; 95% CI 1.01 to 1.06). Compared with nonpediatricians, pediatric providers were less likely to prescribe antibiotics (OR 0.44; 95% CI 0.29 to 0.68); however, pediatricians received higher encounter satisfaction ratings (OR 1.50; 95% CI 1.11 to 2.03).

CONCLUSIONS:
During DTC telemedicine consultations for RTIs, pediatric patients were frequently prescribed antibiotics, which correlated with visit satisfaction. Although pediatricians prescribed antibiotics at a lower rate than other physicians, their satisfaction scores were higher. Further work is required to ensure that antibiotic use during DTC telemedicine encounters is guideline concordant.
Development and Validation of an Easy-to-Implement, Practical Algorithm for the Identification of Molecular Subtypes of Gastric Cancer: Prognostic and Therapeutic Implications
Authors: Koh Jiwon , Lee Keun-Wook , Nam Soo Kyung , Seo An Na , Kim Ji-Won , Kim Jin Won , Park Do Joong , Kim Hyung-Ho , Kim Woo Ho , Lee Hye Seung 
Published: August 2019

Abstract

Background
Gastric cancer (GC) is a heterogeneous disease, and substantial efforts have been made to develop a molecular biology-based classification system for GC. Analysis of the genomic signature is not always feasible, and thus, we aimed to (i) develop and validate a practical immunohistochemistry (IHC)- and polymerase chain reaction (PCR)-based molecular classification of GC and (ii) to assess HER2 status according to this classification.

Materials and Methods
A total of 894 consecutive patients with GC from two individual cohorts (training, n = 507; validation, n = 387) were classified using Epstein-Barr virus (EBV) in situ hybridization, microsatellite instability (MSI) testing, and IHC for E-cadherin and p53.

Results
We were able to classify patients into five groups in the training cohort: group 1 (MSI+), group 2 (EBV−, MSI−, non-epithelial-mesenchymal transition [non-EMT]-like, p53−), group 3 (EBV+), group 4 (EBV−, MSI−, non-EMT-like, p53+), and group 5 (EBV−, MSI−, EMT-like). In the training cohort, each group showed different overall survival (OS) after gastrectomy (p &lt; .001); group 1 had the best prognosis, and group 5 showed the worst survival outcome. The significant impact of the classification system on OS was also verified in the validation cohort (p = .004). HER2 positivity was observed in 6.5% of total population, and most of HER2-positive cases (93.1%) were included in groups 2 and 4.

Conclusion
We developed and validated a modified IHC- and PCR-based molecular classification system in GC, which showed significant impact on survival, irrespective of stage or other clinical variables. We also found close association between HER2 status and non-EMT phenotype in our classification system.

Implications for Practice
Molecular classification of gastric cancer suggested by previous studies mostly relies on extensive genomic data analysis, which is not always available in daily practice. The authors developed a simplified immunohistochemistry- and polymerase chain reaction-based molecular classification of gastric cancer and proved the prognostic significance of this classification, as well as the close association between HER2 status and certain groups of the classification, in the largest consecutive cohort of gastric cancer. Results of this study suggest that this scheme is a cost-effective, easy-to-implement, and feasible way of classifying gastric cancer in daily clinical practice, also serving as a practical tool for aiding therapeutic decisions and predicting prognosis.
Futuro de la gestión integrada “aguas residuales tratadas/agricultura periurbana” en Túnez. Caso del perímetro de riego público (PRP) de Zaouia (Susa)
Authors: Hamrita Abdelkarim , Rejeb Hichem 
Published: August 2019

LLas aguas residuales tratadas eran recursos y su uso en los países áridos y semiáridos es una pregunta de nivel internacional. El artículo aborda el proceso de gestión integrada “aguas residuales tratadas/agricultura periurbana” en Túnez, y sus conflictos ambientales y sociales. La investigación se basa en la combinación del método de evaluación del paisaje, Landscape Character Assessment (LCA), y las entrevistas realizadas con los agricultores de la zona de riego público (ZRP) de Zaouia, lo que permite la caracterización de los paisajes del ámbito de estudio y explicar la percepción de los agricultores, especialmente, sobre el uso de las aguas residuales tratadas y su interacción con otros actores del territorio. Los resultados será una herramienta de toma de la decisión y desarrollar el compromiso entre las aguas residuales tratadas y la agricultura periurbana.
Prognostic value of lipid peroxidation changes in acute poisoning with household drugs “bath salts”
Authors: Sumnaya D B , Iksanov A V , Shkarednykh V Yu , Sadova V A , Kuleshova M V 
Published: August 2019

Aim. To study the state of lipid peroxidation processes in case of psychodisleptic poisoning of the “bath salt” type and to determine the clinical and biochemical markers of a favorable and complicated course of the acute period of poisoning.
Methods. In 347 patients with acute household poisoning (“bath salts”) admitted to the toxicology department of the Chelyabinsk Regional Clinical Hospital №3, the clinical and biochemical features of the acute period of psychodisleptic poisoning (“bath salts”) were studied in a favorable and unfavorable course. Blood and urine samples were taken from all patients, which later underwent chemical and toxicological studies by gas chromatography-mass spectrometry. Also, lipid peroxidation and antioxidant activity were determined in selected blood samples. Lipid peroxidation products were detected in heptane-isopropanol extracts of biological material by spectrophotometry. The intensity of Fe2+-ascorbate-induced lipid peroxidation was determined in E.I. L'vovskaya's modification. The study of patients' samples was carried out in the biochemical laboratory of the regional clinical hospital №3, at the Department of Biochemistry of the Ural state university of physical culture and the South Ural state medical university of Chelyabinsk.
Results. Patients with “bath salts” poisoning in the acute period showed an elevated content of all categories of peroxidation products in the blood serum — by 1.51–1.70 times more than in the control group of healthy people. A decrease in antioxidant activity values I and II by 1.13–1.31 times was also found. With favorable outcomes of poisoning, the level of activation of lipid peroxidation processes decreased with an adequate increase in the activity of the antioxidant system by 1.5–1.6 times. The activation of lipid peroxidation processes in the blood serum accompanied by a decrease in the activity of antioxidant system led to an unfavorable course of the disease and the development of cerebral edema in 18 patients which was fatal.
Conclusion. The clinical and biochemical features of the course of the acute period of poisoning with “bath salts” revealed by us suggest adverse outcomes of the disease with a tendency to an increase in the content of serum lipid peroxidation products in the course of the disease (instead of reducing them) along with a reduction of antioxidant activity; these indicators should be compensated by the use of antioxidant therapy.