bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adiabatic two-step photoexcitation effects in intermediate-band solar cells with quantum dot-in-well structure
Authors: Asahi Shigeo , Kaizu Toshiyuki , Kita Takashi 
Published: May 2019

AbstractWe studied the dynamics of electrons generated by two-step photoexcitation in an intermediate-band solar cell (IBSC) comprising InAs/GaAs/Al0.3Ga0.7As dot-in-well (DWELL) structure using time-resolved photocurrent (TRPC) measurement. The examined IBSC exhibited considerably slower photocurrent decay than a conventional InAs/GaAs quantum dot IBSC, which is due to the extraordinarily long-lived electrons in the DWELL. In order to retrieve the electron lifetime from the decay profile, we developed a model reproducing the observed decay and performed parameter fitting. The fitting results indicate that the electron lifetime in the DWELL is approximately 30 μs. In the two-colour excitation TRPC measurement, we found that an additional infrared (IR) light accelerates the photocurrent decay while the photocurrent increases by approximately 3%, because the additional IR light causes two-step photoexcitation of electrons in the DWELLs towards the conduction band. Furthermore, we demonstrated that the open-circuit voltage increases with increasing of the contribution of the second IR excitation process.
Combinatorial evaluation of phase formation and magnetic properties of FeMnCoCrAl high entropy alloy thin film library
Authors: Marshal A. , Pradeep K. G. , Music D. , Wang L. , Petracic O. , Schneider J. M. 
Published: May 2019

AbstractWe report on the influence of the Al content (from 3.5 to 54 at.%) on phase formation and magnetic properties in FeMnCoCrAl high entropy alloy thin film libraries. Al additions to FeMnCoCr crystallizing in the alpha-Mn structure cause the formation of the body centered cubic (BCC) structure. This is consistent with density functional theory predictions as Al additions give rise to a larger stability for the BCC phase compared to the face centered cubic phase (FCC) which can be rationalized by the formation of a pseudogap at the Fermi level indicating the stabilization of the BCC phase over the FCC phase. Al additions to paramagnetic FeMnCoCr induce ferromagnetism. The largest saturation magnetization was measured for the film containing 8 at.% of Al. As the concentration of non-ferromagnetic Al is increased beyond 8 at.%, the number density of the ferromagnetic species is decreased causing a concomitant decrease in magnetization. This trend is consistent with ab initio predictions of the Al concentration induced changes in the magnetic moment. Based on the experimental and theoretical results presented here the effect of the Al concentration on the phase formation and the magnetic properties of FeMnCoCrAl thin film library can be rationalized.
Rensch’s rule in avian lice: contradictory allometric trends for sexual size dimorphism
Authors: Piross Imre Sándor , Harnos Andrea , Rózsa Lajos 
Published: May 2019

AbstractRensch’s rule (RR) postulates that in comparisons across closely related species, male body size relative to female size increases with the average size of the species. This holds true in several vertebrate and also in certain free-living invertebrate taxa. Here, we document the validity of RR in avian lice using three families (Philopteridae, Menoponidae, and Ricinidae). Using published data on the body length of 989 louse species, subspecies, or distinct intraspecific lineages, we applied phylogenetic reduced major axis regression to analyse the body size of females vs. males while accounting for phylogenetic non-independence. Our results indicate that philopterid and menoponid lice follow RR, while ricinids exhibit the opposite pattern. In the case of philopterids and menoponids, we argue that larger-bodied bird species tend to host lice that are both larger in size and more abundant. Thus, sexual selection acting on males makes them relatively larger, and this is stronger than fecundity selection acting on females. Ricinids exhibit converse RR, likely because fecundity selection is stronger in their case.
Possible role of complement factor H in podocytes in clearing glomerular subendothelial immune complex deposits
Authors: Zoshima Takeshi , Hara Satoshi , Yamagishi Masakazu , Pastan Ira , Matsusaka Taiji , Kawano Mitsuhiro , Nagata Michio 
Published: May 2019

AbstractPodocytes are known to express various complement factors including complement factor H (CFH) and to promote the removal of both subendothelial and subepithelial immune complex (IC) deposits. Using podocyte-selective injury model NEP25 mice and an IgG3-producing hybridoma clone 2B11.3 established by MRL/lpr mice, the present study investigated the role of podocyte complement regulation in only subendothelial IC deposition. In immunotoxin (LMB2) induced fatal podocyte injury (NEP25/LMB2) at day 12, glomerular CFH and C3a receptor (C3aR) expression was decreased as compared with NEP25/vehicle mice. In contrast, in sublytic podocyte injury 5 days after LMB2, glomerular CFH and C3aR expression was increased as compared with NEP25/vehicle mice. Intra-abdominal injection of 2B11.3 hybridoma to NEP25 mice (NEP25/hybridoma) caused IC deposition limited to the subendothelial area associated with unaltered CFH expression. NEP25/hybridoma mice with sublytic podocyte injury (NEP25/hybridoma/LMB2) resulted in increased glomerular CFH expression (1.7-fold) accompanied by decreased subendothelial IC deposition, as compared with NEP25/hybridoma. Immunostaining revealed that CFH was dominantly expressed in podocytes of NEP25/hybridoma/LMB2. In addition, puromycin-induced sublytic podocyte injury promoted CFH expression in immortalized mouse podocytes in vitro. These results suggest that in response to sublytic levels of injury, podocyte induced CFH expression locally and clearance of subendothelial IC deposits.
Influence of the migration of radioactive contaminants in soil, resident occupancy, and variability in contamination on isodose lines for typical Northern European houses
Authors: Hinrichsen Yvonne , Finck Robert , Martinsson Johan , Rääf Christopher , Andersson Kasper Grann 
Published: May 2019

AbstractIn the remedial phase following an accidental radioactive release, it is important that soil decontamination measures are carried out on the areas that contribute most to the radiation dose. In this study, the newly developed concept of isodose lines was applied to the area around typical Swedish dwellings to identify these areas. The influence of the most common building materials in Sweden, wood and brick, and the importance of the positions of doors and windows on the isodose lines were demonstrated for specific positions inside the houses, as well as for the entire house, assuming the residents exhibit typical resident occupancy. Decontamination of the areas within certain isodose lines was shown to result in a greater dose reduction than decontaminating the same area of soil within a certain distance of the house. Furthermore, the impact of vertical migration of the radioactive contaminants in the soil on the isodose lines was studied, showing that the area enclosed by isodose lines decreases over time as the contaminants migrate deeper into the soil. The resulting isodose lines and their change over time are dominated by the downward movement of the contamination in the upper layer of soil. The impact of the variability in contamination on the final isodose lines and their dependence on building materials are demonstrated.
Multivariate analysis reveals significant diuron-related changes in the soil composition of different Brazilian regions
Authors: Chagas Paulo Sérgio Fernandes das , Souza Matheus de Freitas , Dombroski Jeferson Luiz Dallabona , Junior Rubem Silvério de Oliveira , Nunes Glauber Henrique de Sousa , Pereira Gustavo Antônio Mendes , Silva Tatiane Severo , Passos Ana Beatriz Rocha de Jesus , Santos José Barbosa dos , Silva Daniel Valadão 
Published: May 2019

AbstractSorption and desorption determine the amount of an herbicide in soil solution. Therefore, knowledge of the sorption and desorption coefficients in different soils is an essential factor to estimate the potential for environmental contamination by herbicides. We evaluated the feasibility of multivariate and linear discriminant analyses to predict the sorption and desorption capacity of a soil for diuron, one of the most used herbicides on sugarcane plantations. The adsorptive capacity in twenty-seven Brazilian soil samples was estimated using the sorption constant (Kfs) and desorption constant (Kfd) obtained by the Freundlich isotherms. The regression model was created from the sorbed and nonsorbed concentrations of diuron in soils. Ultra-performance liquid chromatography was applied to quantify the diuron concentrations. The multivariate analysis separated the soils into four groups considering the similarity of the following attributes: pH, organic matter, clay, and base saturation. The groups showed a similar pattern of sorption and desorption for diuron: Lom-Lclay: low sorption (5.9 ± 1.2) and high desorption (10.9 ± 0.6); Lclay: low sorption (7.5 ± 1.1) and high desorption (11.4 ± 1.3); Hom-Hclay: high sorption (11.2 ± 1.2) and low desorption (13.8 ± 1.2); HpH-Hclay: high sorption (10.1 ± 1.1) and medium desorption (11.5 ± 1.4). Linear discriminant analysis of these soil attributes was used to classify other soils described in the literature with adsorption capacity. This analysis was able to identify soils with high and low sorption using the pH, organic matter, clay, and base saturation, demonstrating the enormous potential of the technique to group soils with different contamination risks for subterranean waters. Sugarcane crops in northeastern Brazil showed a higher pollution risk through the leaching of diuron. Multivariate analysis revealed significant diuron-related changes in the soil composition of different Brazilian regions; therefore, this statistical analysis can be used to improve understanding of herbicide behavior in soils.
Tissue Interlocking Dissolving Microneedles for Accurate and Efficient Transdermal Delivery of Biomolecules
Authors: Fakhraei Lahiji Shayan , Kim Youseong , Kang Geonwoo , Kim Suyong , Lee Seunghee , Jung Hyungil 
Published: May 2019

AbstractThe interest in safe and efficient transdermal drug delivery systems has been increasing in recent decades. In light of that, polymeric dissolving microneedles (DMNs) were developed as an ideal platform capable of delivering micro- and macro-biomolecules across the skin in a minimally invasive manner. A vast majority of studies, however, suggest that the shape of DMNs, as well as the elastic properties of skin, affects the delivery efficiency of materials encapsulated within DMNs. Likewise, in dynamic tissues, DMNs would easily distend from the skin, leading to inefficient delivery of encapsulated agents. Thus, herein, to improve delivery efficiency of DMN encapsulated agents, a novel hyaluronic acid backbone-based tissue interlocking DMN (TI-DMN) is developed. TI-DMN is simple to fabricate and significantly improves the transdermal delivery efficiency of encapsulated materials compared with traditional DMNs. The enhanced tissue interlocking feature of TI-DMN is achieved through its sharp tip, wide body, and narrow neck geometry. This paper demonstrates that TI-DMN would serve as an attractive transdermal delivery platform to enhance penetration and delivery efficiency of a wide range of biomolecules into the body.
Ultra-small microorganisms in the polyextreme conditions of the Dallol volcano, Northern Afar, Ethiopia
Authors: Gómez Felipe , Cavalazzi Barbara , Rodríguez Nuria , Amils Ricardo , Ori Gian Gabriele , Olsson-Francis Karen , Escudero Cristina , Martínez Jose M. , Miruts Hagos 
Published: May 2019

AbstractThe Dallol geothermal area in the northern part of the Danakil Depression (up to 124–155 meter below sea level) is deemed one of the most extreme environments on Earth. The area is notable for being part of the Afar Depression, an incipient seafloor-spreading center located at the triple junction, between Nubian, Somali and Arabian plates, and for hosting environments at the very edge of natural physical-chemical extremities. The northern part of the Danakil Depression is dominated by the Assale salt plain (an accumulation of marine evaporite deposits) and hosts the Dallol volcano. Here, the interaction between the evaporitic deposit and the volcanisms have created the unique Dallol hot springs, which are highly acidic (pH ~ 0) and saline (saturation) with maximum temperatures ranging between 90 and 109 °C. Here we report for the first time evidence of life existing with these hot springs using a combination of morphological and molecular analyses. Ultra-small structures are shown to be entombed within mineral deposits, which are identified as members of the Order Nanohaloarchaea. The results from this study suggest the microorganisms can survive, and potential live, within this extreme environment, which has implications for understanding the limits of habitability on Earth and on (early) Mars.
Signatures of the non-Maxwellian κ-distributions in optically thin line spectra
Authors: Dudík Jaroslav , Dzifčáková Elena , Del Zanna Giulio , Mason Helen E. , Golub Leon L. , Winebarger Amy R. , Savage Sabrina L. 
Published: May 2019

Aims. We investigated the possibility of diagnosing the degree of departure from the Maxwellian distribution using the Fe XVII–Fe XVIII spectra originating in plasmas in collisional ionization equilibrium, such as in the cores of solar active regions or microflares.
Methods. The original collision strengths for excitation are integrated over the non-Maxwellian electron κ-distributions characterized by a high-energy tail. Synthetic X-ray emission line spectra were calculated for a range of temperatures and κ. We focus on the 6–24 Å spectral range to be observed by the upcoming Marshall Grazing-Incidence X-ray Spectrometer MaGIXS.
Results. We find that many line intensity ratios are sensitive to both T and κ. Best diagnostic options are provided if a ratio involving both Fe XVII and Fe XVIII is combined with another ratio involving lines formed within a single ion. The sensitivity of such diagnostics to κ is typically a few tens of per cent. Much larger sensitivity, of about a factor of two to three, can be obtained if the Fe XVIII 93.93 Å line observed by SDO/AIA is used in conjuction with the X-ray lines.
Conclusions. We conclude that the MaGIXS instrument is well-suited for detection of departures from the Maxwellian distribution, especially in active region cores.
Astrometric calibration for all-sky cameras revisited
Authors: Barghini D. , Gardiol D. , Carbognani A. , Mancuso S. 
Published: May 2019

Context. Several fireball networks deploy all-sky cameras for the observation of bright meteors and bolides. Because the field is heavily distorted, a dedicated astrometric reduction is needed. A precise computation of the astrometric solution is essential to determine reliable orbital elements of the parent body and to recover possible fragments on ground.Aims. The purpose of this article is to assess the astrometric performances of this type of instruments, which is characterized by a wide field of view and small apertures. The currently available parametric models show a high level of complexity and generally suffer from parameter crosstalk and local minimum confinement if the initial estimates are not precisely provided. We address these issues here and propose a solution by adopting a new explicit parametrisation.Methods. The mismatch between the optical axis and the local zenith direction requires a geometric description that includes two centres of symmetry that lie very close to each other on the focal plane, causing an unreliable estimate of the related parameters. The introduction of new physical coordinates overcomes these issues, allowing a direct and independent estimation. We assessed the performances of different centroiding algorithms in the experimental conditions of an undersampled point spread function of reference stars and saturated bolides on video records. We implemented the algorithm for an automatic identification of bright sources on calibration frames and subsequent correlation with catalogue positions using astrometric projections of increasing complexity.Results. The algorithm and the new parametrisation of the astrometric solution are tested against real data from the PRISMA Italian fireball network and ensure good convergence properties for all cameras we tested so far. By processing astrometric data with a few months’ statistics, we can achieve a random projection indeterminacy of the order of 10 arcsec, which is negligible with respect to single measurement errors on the bolide position.
Factor V Leiden Is not a Risk Factor for Arterial Vascular Disease in the Elderly: Results from the Cardiovascular Health Study
Authors: Cushman Mary , Rosendaal Frits R. , Psaty Bruce M. , Cook E. Francis , Valliere J. , Kuller Lewis H. , Tracy Russell P. 
Published: May 2019

SummaryCoagulation factor V Leiden is a risk marker for venous thrombosis. For arterial thrombosis no large study to date has included population-based elderly patients. The Cardiovascular Health Study is a longitudinal study of 5,201 men and women over age 65. With 3.4-year follow-up, we studied 373 incident cases of myocardial infarction (MI), angina, stroke, or transient ischemic attack (TIA), and 482 controls. The odds ratios for each event with heterozygous factor V Leiden were: MI, 0.46 (95% CI 0.17 to 1.25); angina, 1.0 (95% CI 0.45 to 2.23); stroke, 0.77 (95% CI 0.35 to 1.70); TIA, 1.33 (95% CI 0.5 to 3.55); any outcome, 0.83 (95% CI 0.48 to 1.44). Adjustment for cardiovascular risk factors did not change relationships. In older adults factor V Leiden is not a risk factor for future arterial thrombosis.
Cytokine Gene Expression in Human LPS- and IFNγ-stimulated Mononuclear Cells Is Inhibited by Heparin
Authors: Attanasio Monica , Gori Anna Maria , Giusti Betti , Pepe Guglielmina , Comeglio Paolo , Brunelli Tamara , Prisco Domenico , Abbate Rosanna , Gensini Gian Franco , Serneri Gian Gastone Neri 
Published: May 2019

SummaryIn addition to its well-understood anticoagulant activity, heparin is known to modulate a variety of biological functions including immuno-logic responses. In order to investigate whether heparin influences the humoral immunity by interacting with cellular elements and affecting gene expression in blood circulating cells, we studied the effect of heparin on IL-1β, IL-6 and TNFα mRNAs in human lipopolysaccharide(LPS)- or interferon-γ(IFNγ)-stimulated mononuclear cells. The study of mRNA was carried out by an initial PCR screening followed by a Northern blot quantitative analysis. Heparin (0.5 U/ml) turned out to inhibit all three cytokine gene expressions. The mRNA decrease was 37 ± 6% for IL-1 β, 53 ± 3% for IL-6 and 47 ± 4% for TNF α with LPS stimulus. No differences could be observed in the inhibitory effect of heparin on IFNγ-stimulated cells. This effect of heparin was confirmed in a subset of experiments performed on purified monocytes. These results suggest an important immunosuppressive effect of heparin on cell-mediated immune responses.
Intra- and Interindividual Variability of Hemostatic Factors and Traditional Cardiovascular Risk Factors in a Three-year Follow-up
Authors: Salomaa Veikko , Rasi Vesa , Stengård Jari , Vahtera Elina , Pekkanen Juha , Vartiainen Erkki , Ehnholm Christian , Puska Pekka 
Published: May 2019

SummaryElucidation of the key role of thrombosis in cardiovascular disease events has arisen considerable interest in hemostatic factors and in the repeatability of their determinations. Data on long-term repeatability has, however, remained scanty. We examined twice 208 men and 265 women in North Karelia, eastern Finland. The baseline examination was a part of the FINRISK 1992 Hemostasis Study and the age-range of participants was between 45-64 years. The re-examination took place three years later in 1995. Both surveys followed the same protocol and were carried out during the same season. Spearman rank correlation coefficients between 1992 and 1995 measurements of fibrinogen, factor VII coagulant activity (FVII:C), factor VII antigen (FVII:Ag), and plasminogen were among men 0.72, 0.77, 0.46 and 0.56, respectively. For total cholesterol, HDL-cholesterol, triglycerides and diastolic blood pressure the corresponding coefficients were 0.74, 0.83, 0.66, and 0.54. In women, the coefficient of fibrinogen was lower than in men, 0.62, otherwise the results were similar. Of men belonging to the highest quarter of fibrinogen, FVII:C, FVII:Ag and plasminogen in 1992, 65%, 60%, 53% and 60% belonged to the highest quarter of respective distributions also in 1995. In women, the corresponding proportions were 64%, 65%, 46% and 58%. The modest repeatability of FVII:Ag and plasminogen was mainly due to the high intraindividual variability. However, in comparisons of plasma levels between two groups, relatively small sample sizes seemed to give adequate statistical power to detect possible differences in FVII:Ag and plasminogen. In conclusion, the long-term repeatability of fibrinogen and FVII:C is similar to that of triglycerides and even better than that of diastolic blood pressure, but somewhat lower than the repeatability of total cholesterol. FVII:Ag and plasminogen did not have very good repeatability and more than one measurement of them should be considered if they are used as predictors of cardiovascular disease in prospective studies.
Distribution of Tissue Plasminogen Activator Insertion/Deletion Polymorphism in Myocardial Infarction and Control Subjects
Authors: Steeds Rick , Adams Matthew , Smith Pamela , Channer Kevin , Samani Nilesh J. 
Published: May 2019

SummaryAn insertion (I)/deletion (D) polymorphism in the tissue plasminogen activator (TPA) gene locus has recently been reported to be associated with the risk of myocardial infarction (MI) with increased risk in II/ID subjects compared with DD subjects. To investigate this further, we analysed 529 acute MI cases and 525 population-based control subjects recruited in two centers (Leicester and Sheffield, UK). We found no difference between cases and controls in TPA I/D allele frequencies (cases I = 0.574, controls I = 0.582, p = 0.74) or genotype distribution (cases II 33%, ID 48%, DD 19%; controls II 34%, ID 49%, DD 17%, p = 0.88). Compared with the DD genotype, the age, sex and centre adjusted odds ratios for MI for II genotype was 0.95 (95% confidence interval, 0.64 – 1.40, p = 0.85) and that for ID genotype was 0.89 (0.62-1.27, p = 0.56). There was no significant effect modification by smoking status, body mass index or cholesterol level. There was no difference in the reported frequency of positive family history of coronary heart disease or mean age at MI in the different genotype groups. We conclude that in our populations the TPA I/D polymorphism is not a major independent risk factor for myocardial infarction.