bluuebunny/crossref_metadata_2025_split huggingface dataset:
English Can Be Jewish but Hebrew Cannot: Code-switching Patterns among Yiddish-speaking Hasidic Women
Authors: Assouline Dalit 
Published: June 2019

Abstract
This article discusses why and how English was able to turn into a contemporary Jewish language among Yiddish-speaking American Hasidic Jews, in marked contrast to Israeli Hebrew (IH), which has not been similarly adjusted. One reason is that communal attitudes towards English are not as ideologically charged as compared to the “zealous” opposition to IH. Another reason is that English is able to undergo phonological and lexical modifications that enable Hasidic English to function as an ethnolect used within the community. This process, however, is linguistically more complex for IH, which thus remains an outsider language among Israeli Yiddish-speaking Haredim. The outsider status of IH versus the insider status of Hasidic English is reflected in the code-switching patterns attested among Yiddish public speakers, resulting in a common and effortless pattern of Yiddish-English switching among American speakers, as opposed to rare and marked instances of switches to IH among Israeli speakers.
American Hasidic Yiddish Pedagogical Materials: A Sociological and Sociolinguistic Survey of 50 Years of Post-War Publishing
Authors: Kutzik Jordan 
Published: June 2019

Abstract
After arriving in the United States after WWII, Hasidic Jews quickly established educational publishing houses in Yiddish in New York. How these publications developed and changed from the 1950s to the present day reveals a great deal about how Hasidim adjusted to American life, how their Yiddish changed during this period, and how competing linguistic ideologies emerged to address these changes. This article provides an overview of three generations of American Hasidic Yiddish pedagogical materials, using a sample of books, oral-medium games, and a family magazine’s children’s section. It uses close reading and sociolinguistic analysis to examine how the perception of Yiddish among Hasidim evolved into perceiving the language as a semi-holy tongue uniquely capable of transmitting religious and cultural values. This article will explore how this changing perception has caused Hasidic communities to reevaluate how they seek to transmit the language to future generations.
Meaning and Captivity in Classical Arabic Philology
Authors: Larsen David 
Published: June 2019

Abstract
This article takes a close look at the word maʿnā as analyzed by Abbasid-era authorities on the Arabic language, chiefly Ibn Fāris (d. 395/1004). The word’s context-sensitivity and polysemy are well known; less well appreciated are the lexical and morphological preconditions for maʿnā’s diversity of meanings across the disciplines. Even less well studied (though widely quoted in lexicographical literature) is the anonymous basīṭ-meter couplet that Ibn Fāris cites in al-Ṣāḥibī fī fiqh al-lugha as a locus probans for the word. The speaker in these verses boasts of ransoming a bound captive (ʿānī), using maʿnā to refer to the captive’s abject state. There is evidence to suggest that the verses once featured in a lost work of the philologist Abū Naṣr al-Bāhilī (d. 231/855) called Kitāb Abyāt al-maʿānī. This was an anthology of verses framed like riddles whose interpretation hinged on double meanings and rare metaphors, and its form and content may be judged by numerous outtakes preserved in later anthologies and lexica. The affiliation of Ibn Fāris’s verses to Kitāb Abyāt al-maʿānī would confirm that the derivation of maʿnā truly is a puzzle with multiple answers. To contemplate its parameters is to uncover a paradigm for meaning in which noetic intention and phenomenological exposure are figurative correlates of bodily captivity and duress.
Hersiliola brachyplura Strand, 1913 belongs to Oecobius (Araneae: Oecobiidae)
Authors: FET VICTOR 
Published: June 2019

Under the spider family Hersiliidae, Platnick (2008) lists as nomina dubia the following two taxa described from “Jaffa-Rehoboth [Rehovot]” in Israel: Hersiliola brachyplura Strand, 1913 and H. brachyplura demaculata Strand, 1914. Platnick (2008) refers to Levy (2003: 25) but Levy, only commented that these taxa belong to the genus Oecobius (Oecobiidae), referring to “Victor Fet, in litt.” for that opinion, without making a formal transfer.
The Use of Uncertainty Quantification for the Empirical Modeling of Wind Turbine Icing
Authors: Molinder Jennie , Körnich Heiner , Olsson Esbjörn , Hessling Peter 
Published: June 2019

AbstractA novel uncertainty quantification method is used to evaluate the impact of uncertainties of parameters within the icing model in the modeling chain for icing-related wind power production loss forecasts. As a first step, uncertain parameters in the icing model were identified from the literature and personal communications. These parameters are the median volume diameter of the hydrometeors, the sticking efficiency for snow and graupel, the Nusselt number, the shedding factor, and the wind erosion factor. The sensitivity of these parameters on icing-related wind power production losses is examined. An icing model ensemble representing the estimated parameter uncertainties is designed using so-called deterministic sampling and is run for two periods over a total of 29 weeks. Deterministic sampling allows an exact representation of the uncertainty and, in future applications, further calibration of these parameters. Also, the number of required ensemble members is reduced drastically relative to the commonly used random-sampling method, thus enabling faster delivery and a more flexible system. The results from random and deterministic sampling are compared and agree very well, confirming the usefulness of deterministic sampling. The ensemble mean of the nine-member icing model ensemble generated with deterministic sampling is shown to improve the forecast skill relative to one single forecast for the winter periods. In addition, the ensemble spread provides valuable information as compared with a single forecast in terms of forecasting uncertainty. However, addressing uncertainties in the icing model alone underestimates the forecast uncertainty, thus stressing the need for a fully probabilistic approach in the modeling chain for wind power forecasts in a cold climate.
Spatial Variability of Winds and HRRR–NCEP Model Error Statistics at Three Doppler-Lidar Sites in the Wind-Energy Generation Region of the Columbia River Basin
Authors: Pichugina Y. L. , Banta R. M. , Bonin T. , Brewer W. A. , Choukulkar A. , McCarty B. J. , Baidar S. , Draxl C. , Fernando H. J. S. , Kenyon J. , Krishnamurthy R. , Marquis M. , Olson J. , Sharp J. , Stoelinga M. 
Published: June 2019

AbstractAnnually and seasonally averaged wind profiles from three Doppler lidars were obtained from sites in the Columbia River basin of east-central Oregon and Washington, a major region of wind-energy production, for the Second Wind Forecast Improvement Project (WFIP2) experiment. The profile data are used to quantify the spatial variability of wind flows in this area of complex terrain, to assess the HRRR–NCEP model’s ability to capture spatial and temporal variability of wind profiles, and to evaluate model errors. Annually averaged measured wind speed differences over the 70-km extent of the lidar measurements reached 1 m s−1 within the wind-turbine rotor layer, and 2 m s−1 for 200–500 m AGL. Stronger wind speeds in the lowest 500 m occurred at sites higher in elevation, farther from the river, and farther west—closer to the Cascade Mountain barrier. Validating against the lidar data, the HRRR model underestimated strong wind speeds (>12 m s−1) and, consequently, their frequency of occurrence, especially at the two lowest-elevation sites, producing annual low biases in rotor-layer wind speed of 0.5 m s−1. The RMSE between measured and modeled winds at all sites was about 3 m s−1 and did not degrade significantly with forecast lead time. The nature of the model errors was different for different seasons. Moreover, although the three sites were located in the same basin terrain, the nature of the model errors was different at each site. Thus, if only one of the sites had been instrumented, different conclusions would have been drawn as to the major sources of model error, depending on where the measurements were made.
Balanced and Radiating Wave Responses to Diurnal Heating in Tropical Cyclone–Like Vortices Using a Linear Nonhydrostatic Model
Authors: Evans Rebecca C. , Nolan David S. 
Published: June 2019

Abstract
The diurnal cycle (DC) in the cirrus canopy of tropical cyclones (TCs) is a well-documented phenomenon. While early studies linked the DC in the area of the cirrus canopy to a DC in the strength of eyewall convection, later studies considered it a direct response to the DC of radiation in the cirrus canopy. In this study, an idealized linear model is used to examine the extent to which linear dynamics can capture the DC in TCs, in particular the transition between balanced and radiating responses to diurnal heating. The model heat forcing is physically motivated by the diabatic heating output from a realistic simulation, which illustrates the presence of a DC in moist convective heating and radiative heating in the eyewall, and a DC in radiative heating in the cirrus canopy. This study finds that the DCs of heating in the eyewall yield a response that is restricted to inside the RMW by the high inertial stability in the inner core. The DC of radiative heating in the cirrus canopy yields a response throughout the entire cyclone. Lower-frequency responses, of diurnal and semidiurnal frequency, are balanced throughout much of the cyclone. High-frequency waves with periods under 8 h, created at sunrise and sunset, can radiate outward and downward. These results indicate that diurnal responses are balanced in the majority of a TC and originate in the cirrus canopy, instead of the eyewall. The DC in cirrus canopy vertical motion also appears to originate in the cirrus canopy.
Statistical Learning Methods as a Basis for Skillful Seasonal Temperature Forecasts in Europe
Authors: Kämäräinen Matti , Uotila Petteri , Karpechko Alexey Yu. , Hyvärinen Otto , Lehtonen Ilari , Räisänen Jouni 
Published: June 2019

AbstractA statistical learning approach to produce seasonal temperature forecasts in western Europe and Scandinavia was implemented and tested. The leading principal components (PCs) of sea surface temperature (SST) and the geopotential at the 150-hPa level (GPT) were derived from reanalysis datasets and used at different lags (from one to five seasons) as predictors. Random sampling of both the fitting years and the potential predictors together with the Least Absolute Shrinkage and Selection Operator regression (LASSO) was used to create a large ensemble of statistical models. Applying the models to independent test years shows that the ensemble performs well over the target areas and that the ensemble mean is more accurate than the best individual ensemble member on average. Skillful results were especially found for summer and fall, with the anomaly correlation coefficient values ranging between 0.41 and 0.68 for these seasons. The correct simulation of decadal trends, using sufficiently long time series for fitting (70 years), and the use of lagged predictors increased the prediction skill. The decadal-scale variability of SST, most importantly the Atlantic multidecadal oscillation (AMO), and different PCs of GPT are the most important individual predictors among all predictors. Both SST and GPT bring equally much predictive power, although their importance is different in different seasons.
Analysis of Large-Scale Dynamics and Gravity Waves under Shedding of Inactive Flow Components
Authors: Gassmann Almut 
Published: June 2019

Abstract
The Ertel’s potential vorticity (EPV) budget equation does not see the contribution of an inactive EPV flux component ∇θ × ∇B because it drops out when taking the divergence. A part of the actual EPV flux can always be interpreted as such an inactive component and is thus likewise shed from the EPV budget equation. The deviation from this inactive EPV flux is called the active EPV flux and the associated wind is called the active wind. The horizontal active wind is comparable to the ageostrophic wind. The vertical active wind component is similar to the isentropic displacement vertical wind. In contrast to the actual wind, the vertical active wind does not vanish at the surface, because the inactive wind blows along isentropes, which may intersect the ground. Transformed governing equations are derived as functions of the active wind components. The terms on the right of the transformed equations can be scrutinized with respect to their effects on the evolution of the atmospheric state. An idealized baroclinic wave in a dry atmosphere is discussed with focus on the fronts and the generation or depletion of kinetic energy. Since the vertical inactive wind does not necessarily vanish at the surface, the arising vertical active wind is responsible for the cooling (raising of isentropes) and the warming (sinking of isentropes) in the different regions of a cyclone. The new method allows for a unique separation of gravity waves and vortical modes. This facilitates the analysis of gravity wave generation and propagation from jets and fronts.
An NWP Model Intercomparison of Surface Weather Parameters in the European Arctic during the Year of Polar Prediction Special Observing Period Northern Hemisphere 1
Authors: Køltzow Morten , Casati Barbara , Bazile Eric , Haiden Thomas , Valkonen Teresa 
Published: June 2019

AbstractIncreased human activity in the Arctic calls for accurate and reliable weather predictions. This study presents an intercomparison of operational and/or high-resolution models in an attempt to establish a baseline for present-day Arctic short-range forecast capabilities for near-surface weather (pressure, wind speed, temperature, precipitation, and total cloud cover) during winter. One global model [the high-resolution version of the ECMWF Integrated Forecasting System (IFS-HRES)], and three high-resolution, limited-area models [Applications of Research to Operations at Mesoscale (AROME)-Arctic, Canadian Arctic Prediction System (CAPS), and AROME with Météo-France setup (MF-AROME)] are evaluated. As part of the model intercomparison, several aspects of the impact of observation errors and representativeness on the verification are discussed. The results show how the forecasts differ in their spatial details and how forecast accuracy varies with region, parameter, lead time, weather, and forecast system, and they confirm many findings from mid- or lower latitudes. While some weaknesses are unique or more pronounced in some of the systems, several common model deficiencies are found, such as forecasting temperature during cloud-free, calm weather; a cold bias in windy conditions; the distinction between freezing and melting conditions; underestimation of solid precipitation; less skillful wind speed forecasts over land than over ocean; and difficulties with small-scale spatial variability. The added value of high-resolution limited area models is most pronounced for wind speed and temperature in regions with complex terrain and coastlines. However, forecast errors grow faster in the high-resolution models. This study also shows that observation errors and representativeness can account for a substantial part of the difference between forecast and observations in standard verification.
Analysis of factor V in zebrafish demonstrates minimal levels needed for early hemostasis
Authors: Weyand Angela C. , Grzegorski Steve J. , Rost Megan S. , Lavik Kari I. , Ferguson Allison C. , Menegatti Marzia , Richter Catherine E. , Asselta Rosanna , Duga Stefano , Peyvandi Flora , Shavit Jordan A. 
Published: June 2019

AbstractIn humans, coagulation factor V (FV) deficiency is a rare, clinically heterogeneous bleeding disorder, suggesting that genetic modifiers may contribute to disease expressivity. Zebrafish possess many distinct advantages including high fecundity, optical clarity, external development, and homology with the mammalian hemostatic system, features that make it ideal for genetic studies. Our aim was to study the role of FV in zebrafish through targeted mutagenesis and apply the model to the study of human F5 variants. CRISPR-mediated genome editing of the zebrafish f5 locus was performed, generating mutants homozygous for a 49 base pair deletion in exon 4. Thrombus formation secondary to vascular endothelial injury was absent in f5−/− mutant embryos and larvae. Despite this severe hemostatic defect, homozygous mutants survived before succumbing to severe hemorrhage in adulthood. Human F5 variants of uncertain significance from patients with FV deficiency were evaluated, and the causative mutations identified and stratified by their ability to restore thrombus formation in larvae. Analysis of these novel mutations demonstrates variable residual FV function, with minimal activity being required to restore hemostasis in response to laser-induced endothelial injury. This in vivo evaluation may be beneficial for patients whose factor activity levels lack correlation with bleeding symptomatology, although limitations exist. Furthermore, homozygous mutant embryos tolerate what is a severe and lethal defect in mammals, suggesting the possibility of species-specific factors enabling survival, and allowing further study not possible in the mouse. Identification of these factors or other genetic modifiers could lead to novel therapeutic modalities.
Human peripheral blood DNAM-1neg NK cells are a terminally differentiated subset with limited effector functions
Authors: Stannard Kimberley A. , Lemoine Sébastien , Waterhouse Nigel J. , Vari Frank , Chatenoud Lucienne , Gandhi Maher K. , Martinet Ludovic , Smyth Mark J. , Guillerey Camille 
Published: June 2019

AbstractNatural killer (NK) cells are a heterogeneous population of innate lymphocytes whose potent anticancer properties make them ideal candidates for cellular therapeutic application. However, our lack of understanding of the role of NK cell diversity in antitumor responses has hindered advances in this area. In this study, we describe a new CD56dim NK cell subset characterized by the lack of expression of DNAX accessory molecule-1 (DNAM-1). Compared with CD56bright and CD56dimDNAM-1pos NK cell subsets, CD56dimDNAM-1neg NK cells displayed reduced motility, poor proliferation, lower production of interferon-γ, and limited killing capacities. Soluble factors secreted by CD56dimDNAM-1neg NK cells impaired CD56dimDNAM-1pos NK cell–mediated killing, indicating a potential inhibitory role for the CD56dimDNAM-1neg NK cell subset. Transcriptome analysis revealed that CD56dimDNAM-1neg NK cells constitute a new mature NK cell subset with a specific gene signature. Upon in vitro cytokine stimulation, CD56dimDNAM-1neg NK cells were found to differentiate from CD56dimDNAM-1pos NK cells. Finally, we report a dysregulation of NK cell subsets in the blood of patients diagnosed with Hodgkin lymphoma and diffuse large B-cell lymphoma, characterized by decreased CD56dimDNAM-1pos/CD56dimDNAM-1neg NK cell ratios and reduced cytotoxic activity of CD56dimDNAM-1pos NK cells. Altogether, our data offer a better understanding of human peripheral blood NK cell populations and have important clinical implications for the design of NK cell–targeting therapies.
Enhanced labile plasma iron in hematopoietic stem cell transplanted patients promotes Aspergillus outgrowth
Authors: Petzer Verena , Wermke Martin , Tymoszuk Piotr , Wolf Dominik , Seifert Markus , Ovaçin Rıdvan , Berger Sylvia , Orth-Höller Dorothea , Loacker Lorin , Weiss Günter , Haas Hubertus , Platzbecker Uwe , Theurl Igor 
Published: June 2019

Key Points
Serum-enhanced labile plasma iron in patients undergoing allogeneic HSCT is critical for Aspergillus fumigatus growth in vitro. Transferrin iron in serum is inaccessible for A fumigatus, and uptake of iron in the form of eLPI involves fungal siderophores.
Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial
Authors: Leiter Lawrence A. , Bain Stephen C. , Hramiak Irene , Jódar Esteban , Madsbad Sten , Gondolf Theis , Hansen Thomas , Holst Ingrid , Lingvay Ildiko 
Published: June 2019

Abstract
Background
The SUSTAIN 6 trial demonstrated that once-weekly semaglutide (0.5 and 1.0 mg) significantly reduced major adverse cardiovascular (CV) events (MACE) vs placebo in subjects with type 2 diabetes (T2D) and high CV risk. The effects of gender, age and baseline CV risk on outcomes are important considerations for further study.

Methods
Subjects were grouped according to gender, age (50–65 years and > 65 years), and CV risk profile at baseline (prior myocardial infarction [MI] or stroke vs no prior MI or stroke, and established CV disease [CVD] vs CV risk factors alone, including subjects with chronic kidney disease). Time to MACE and its individual components (CV death, nonfatal MI, nonfatal stroke), hospitalization for unstable angina or heart failure, and revascularization (coronary and peripheral) were analyzed for all subgroups. Additional analyses were performed for gender and age to investigate change from baseline in HbA1c and body weight, as well as tolerability.

Results
A total of 3297 subjects were included. The majority of subjects (60.7%) were male; 43% were > 65 years of age; 41.5% had a history of MI or stroke; and 76.8% had established CVD. Compared with placebo, semaglutide reduced the risk of the first occurrence of MACE and each MACE component consistently across all subgroups (gender, age, and baseline CV risk profile). Revascularizations, HbA1c and body weight were also reduced consistently across all subgroups compared with placebo. Gastrointestinal adverse events in all treatment groups were more common among women than men, but rates of premature treatment discontinuation were similar for both genders.

Conclusions
In this post hoc analysis of SUSTAIN 6, once-weekly semaglutide vs placebo reduced the risk of MACE in all subjects included in the trial, regardless of gender, age, or baseline CV risk profile.
Trial registry Clinicaltrials.gov, Identifying number: NCT01720446, Date of registration: October 29, 2012
Canagliflozin for Japanese patients with chronic heart failure and type II diabetes
Authors: Sezai Akira , Sekino Hisakuni , Unosawa Satoshi , Taoka Makoto , Osaka Shunji , Tanaka Masashi 
Published: June 2019

Abstract
Background
Reports that sodium glucose cotransporter 2 inhibitors decrease cardiovascular death and events in patients with diabetes have attracted attention in the cardiology field. We conducted a study of canagliflozin in patients with chronic heart failure and type II diabetes.

Methods
Thirty-five Japanese patients with chronic heart failure and type II diabetes were treated with canagliflozin for 12 months. The primary endpoints were the changes of subcutaneous, visceral, and total fat areas at 12 months determined by computed tomography. Secondary endpoints included markers of glycemic control, renal function, and oxidative stress, as well as lipid parameters, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), flow-mediated dilation (FMD), and echocardiographic left ventricular function.

Results
All fat areas (subcutaneous, visceral, and total) showed a significant decrease at 12 months. ANP and BNP also decreased significantly, along with improvement of renal function, oxidized LDL, and E/e′, FMD increased significantly after canagliflozin treatment.

Conclusion
Canagliflozin demonstrated cardiac and renal protective effects as well as improving oxidative stress, diastolic function, and endothelial function. This drug was effective in patients who had heart failure with preserved ejection fraction and could become first-line therapy for such patients with diabetes.
Trial registration UMIN (http://www.umin.ac.jp/), Study ID: UMIN000021239