bluuebunny/crossref_metadata_2025_split huggingface dataset:
СУБСТРАТНАЯ СПЕЦИФИЧНОСТЬ АЦИЛ-ЛИПИДНОЙ ?9-ДЕСАТУРАЗЫ ЖИРНЫХ КИСЛОТ ИЗ ЦИАНОБАКТЕРИИ CYANOBACTERIUM SP. IPPAS B-1200 С НЕОБЫЧНЫМ ЖИРНОКИСЛОТНЫМ СОСТАВОМ, "Физиология растений"
Authors: Стариков А. Ю. , Усербаева А.А. , Миронов К.С. , Сидоров Р.А. , Заядан Б.К. , Бедбенов В.С. , Синетова М.А. , Лось Д.А. 
Published: August 2018

Cyanobacterium sp. IPPAS B-1200 характеризуется высоким содержанием в мембранных липидах таких жирных кислот (ЖК) как миристиновая (14:0-30%) и миристолеиновая (14:1 9-10%). Таким образом, “короткие” ЖК составляют 40% от общей массы ЖК, что крайне необычно для цианобактерий. Мононенасыщенная пальмитолеиновая кислота (16:1 9) также достигает 40% от суммы ЖК. Мы определили нуклеотидную последовательность генома этой цианобактерии и обнаружили в нем лишь один ген десатуразы ЖК, кодирующий ацил-липидную 9-десатуразу DesC1. Для определения спе- цифичности DesC1 к длине ЖК этот ген клонировали и экспрессировали в клетках Escherichia coli. Результаты показывают, что десатураза DesC1 проявляет активность в положении 9 неспецифично по отношению к длине цепи ЖК и способна образовывать двойные связи в С14, С16 и С18 ЖК. Это свидетельствует о том, что наличие всех мононесащенных кислот в клетках Cyanobacterium определяется активностью одной единственной 9-десатуразы.
ЗАКРЫВАНИЕ УСТЬИЦ ХВОИ СОСНЫ В УСЛОВИЯХ ВОДНОГО ДЕФИЦИТА ОПРЕДЕЛЯЕТСЯ СНИЖЕНИЕМ ВОДНОГО ПОТЕНЦИАЛА АПОПЛАСТА МЕЗОФИЛЛА ПОДУСТЬИЧНОЙ ПОЛОСТИ, "Физиология растений"
Authors: Воронин П.Ю. , Рахманкулова З.Ф. , Тарнопольская Е. Е. , Кузнецов Вл. В. 
Published: August 2018

В контролируемых условиях исследовали ответные реакции сеянцев сосны (Pinus sylvestris L.) на разный по интенсивности водный дефицит, индуцируемый полиэтиленгликолем 6000 (ПЭГ) (от -0.15 до -1.5 МПа). При этом определяли сухую массу побегов и корней растений, максимальный квантовый выход флуоресценции (Fv /Fm) и нефотохимическое тушение (NPQ) хлорофилла, фотосинтетический СО2/Н2О-газообмен и темновое дыхание хвои, водный потенциал апопласта мезофилла в подустьичной полости хвои. В условиях индуцированного водного дефицита наблюдали торможение роста сеянцев, снижение интенсивности фотосинтеза, транспирации и содержания фотосинтетических пигментов. Впервые показано, что исполнительным механизмом закрывания устьиц как физиологической нормы реакции хвои сеянцев сосны на водный дефицит является снижение водного потенциала апопласта мезофилла подустьичной полости.
ФИТАЗЫ И?ПЕРСПЕКТИВЫ ИХ ПРИМЕНЕНИЯ (ОБЗОР), "Прикладная биохимия и микробиология"
Authors: Гесслер Н.Н. , Сердюк Е. Г. , Исакова Е.П. , Дерябина Ю.И. 
Published: August 2018

Фитазы растительного и микробного происхождения высвобождают фосфаты из трудно растворимых фитатов, делая их доступными для усвоения. В обзоре рассмотрены биохимические свойства фитаз, области применения и перспективы использования. Введение фитаз в корма сельскохозяйственных животных повышает выход продукции без дополнительных затрат на внесение минеральных фосфатов. Наличие продуцентов фитаз в почве позволяет уменьшить дозу вносимых минеральных фосфатных удобрений и таким образом снижает риск эвтрофикации водоемов.
ОПТИМИЗАЦИЯ МЕТОДА МЕТАБОЛОМНОГО ПРОФИЛИРОВАНИЯ ЛЮЦЕРНЫ ХМЕЛЕВИДНОЙ И?ГОРОХА ПОСЕВНОГО, "Прикладная биохимия и микробиология"
Authors: Пузанский Р.К. , Емельянов В.В. , Клюкова М. С. , Шаварда А.Л. , Штарк О.Ю. , Юрков А.П. , Шишова М.Ф. 
Published: August 2018

Метаболическое профилирование представляет собой ключевой подход для современных биологических фундаментальных и прикладных исследований. Сравнительный анализ способов экстракции метаболитов гороха посевного и люцерны хмелевидной позволил подобрать оптимальные условия их выделения и последующего детектирования методом газовой хроматографии, сопряженной с масс-спектрометрией. Показана адекватность такого метода для оценки органо- и видоспецифичности метаболических профилей корней и листьев у растений гороха и люцерны хмелевидной.
АММОНОИДНАЯ ЗОНА YAKUTOSIRENITES ARMIGER СЕВЕРО-ВОСТОКА АЗИИ?-?РЕПЕРНЫЙ УРОВЕНЬ БОРЕАЛЬНО-ТЕТИЧЕСКОЙ КОРРЕЛЯЦИИ НИЖНЕГО КАРНИЯ, "Стратиграфия. Геологическая корреляция"
Authors: Константинов А.Г. 
Published: August 2018

Рассмотрены проблемы бореально-тетической корреляции нижнего карния и методические подходы их решения. Проведена ревизия состава и распространения аммоноидей в наиболее представительных разрезах верхней части нижнего карнийского подъяруса Северо-Востока Азии - в Северном Приохотье, Северном Верхоянье и в центральной части о-ва Котельный. Впервые палеонтологически обосновано выделение аммоноидной зоны Yakutosirenites armiger и показаны ее границы в разрезе нижнего карния в бассейне р. Тихая о-ва Котельный. Уточнен и дополнен состав комплекса аммоноидей зоны armiger на рассматриваемой территории, в котором наряду с местными таксонами аммоноидей (Yakutosirenites armiger (Vozin), Arctophyllites okhotensis Konstantinov) и редкими экзотическими формами, имеющими южное происхождение (Siberioklipsteinia dagysi Konstantinov), установлено присутствие космополитного рода Sirenites. Рассмотрена история выделения и морфология рода Sirenites, приведены сведения о его стратиграфическом и географическом распространении. Наличие в комплексе аммоноидей зоны armiger Северо-Востока Азии видов Sirenites senticosus (Dittmar) и S. ovinus Tozer обеспечивает ее прямую корреляцию c тетическими разрезами, а именно с зонами Austrotrachyceras obesum и Sirenites nanseni Британской Колумбии, с зоной Austrotrachyceras austriacum альпийской шкалы и их эквивалентами, широко распространенными во многих тетических регионах. Это дает основание рассматривать зону armiger Северо-Востока Азии в качестве реперного уровня бореально-тетической корреляции нижнего карния.
БЕЛЕМНИТЫ И БИОСТРАТИГРАФИЯ НИЖНЕГО БАТА ЦЕНТРА И ЮГА ВОСТОЧНО-ЕВРОПЕЙСКОЙ ПЛАТФОРМЫ. ЧАСТЬ 2. CYLINDROTEUTHIDIDAE И BELEMNOTHEUTIDIDAE, "Стратиграфия. Геологическая корреляция"
Authors: Ипполитов А. П. 
Published: August 2018

Проведена ревизия белемнитов из нижнебатских отложений Русской плиты на основании изучения двух опорных разрезов - Плетнёвского и Сокурского карьеров. Во второй части работы рассматриваются представители сем. Cylindroteuthididae, а также “безростровые” белемниты сем. Belemnotheutididae. Среди цилиндротеутидид, встреченных только в Сокурском карьере, установлено присутствие 4 видов, относящихся к единственному роду Pachyteuthis, включая впервые описываемый вид P. mittai sp. nov. Для белемнотеутидид установлено присутствие единственного вида Acanthoteuthis foliorostris sp. nov., который является первой достоверной находкой рода Acanthoteuthis в докелловейских отложениях. На основе изучения вертикальных изменений признаков у цилиндротеутидид выделены 2 биогоризонта, предложены усовершенствования существующей схемы расчленения нижнего бата Поволжья и его корреляции с разрезами в бассейне р. Печора по белемнитам. По результатам всей ревизии представлена комплексная зональная и инфразональная схема расчленения нижнебатских отложений Поволжья по белемнитам. Наличие в раннем бате в Среднерусском море эндемичных таксонов родового ранга, происходящих от аркто-бореальных иммигрантов, позволяет трактовать формирование фауны белемнитов указанного возраста как ранний изолированный эпизод обособления Бореально-Атлантической провиции по белемнитам. Особенности развития фауны головоногих в раннем бате Русской плиты указывают на двухфазный характер формирования меридионального пролива, соединявшего Среднерусское море с арктическими бассейнами, а также позволяют обосновать предположение о кратковременном открытии субширотного Припятского пролива в момент максимума трансгрессии.
All‐Silicon Broadband Ultraviolet Metasurfaces
Authors: Deng Yang , Wang Xi , Gong Zilun , Dong Kaichen , Lou Shuai , Pégard Nicolas , Tom Kyle B. , Yang Fuyi , You Zheng , Waller Laura , Yao Jie 
Published: August 2018

AbstractFeaturing high photon energy and short wavelength, ultraviolet (UV) light enables numerous applications such as high‐resolution imaging, photolithography, and sensing. In order to manipulate UV light, bulky optics are usually required, and hence do not meet the fast‐growing requirements of integration in compact systems. Recently, metasurfaces have shown unprecedented control of light, enabling substantial miniaturization of photonic devices from terahertz to visible regions. However, material challenges have hampered the realization of such functionalities at shorter wavelengths. Herein, it is experimentally demonstrated that all‐silicon (Si) metasurfaces with thicknesses of only one‐tenth of the working wavelength can be designed and fabricated to manipulate broadband UV light with efficiencies comparable to plasmonic metasurface performance in infrared (IR). Also, for the first time, photolithography enabled by metasurface‐generated UV holograms is shown. Such performance enhancement is attributed to increased scattering cross sections of Si antennas in the UV range, which is adequately modeled via a circuit. The new platform introduced here will deepen the understanding of light–matter interactions and introduce even more material options to broadband metaphotonic applications, including those in integrated photonics and holographic lithography technologies.
Achieving a Record‐High Yield Rate of 120.9 for N2 Electrochemical Reduction over Ru Single‐Atom Catalysts
Authors: Geng Zhigang , Liu Yan , Kong Xiangdong , Li Pai , Li Kan , Liu Zhongyu , Du Junjie , Shu Miao , Si Rui , Zeng Jie 
Published: August 2018

AbstractThe electrochemical reduction of N2 into NH3 production under ambient conditions represents an attractive prospect for the fixation of N2. However, this process suffers from low yield rate of NH3 over reported electrocatalysts. In this work, a record‐high activity for N2 electrochemical reduction over Ru single atoms distributed on nitrogen‐doped carbon (Ru SAs/N‐C) is reported. At −0.2 V versus reversible hydrogen electrode, Ru SAs/N‐C achieves a Faradaic efficiency of 29.6% for NH3 production with partial current density of −0.13 mA cm−2. Notably, the yield rate of Ru SAs/N‐C reaches 120.9 , which is one order of magnitude higher than the highest value ever reported. This work not only develops a superior electrocatalyst for NH3 production, but also provides a guideline for the rational design of highly active and robust single‐atom catalysts.
Fast Exfoliation and Functionalisation of Two‐Dimensional Crystalline Carbon Nitride by Framework Charging
Authors: Jia Jingjing , White Edward R. , Clancy Adam J. , Rubio Noelia , Suter Theo , Miller Thomas S. , McColl Kit , McMillan Paul F. , Brázdová Veronika , Corà Furio , Howard Christopher A. , Law Robert V. , Mattevi Cecilia , Shaffer Milo S. P. 
Published: August 2018

AbstractTwo‐dimensional (2D) layered graphitic carbon nitride (gCN) nanosheets offer intriguing electronic and chemical properties. However, the exfoliation and functionalisation of gCN for specific applications remain challenging. We report a scalable one‐pot reductive method to produce solutions of single‐ and few‐layer 2D gCN nanosheets with excellent stability in a high mass yield (35 %) from polytriazine imide. High‐resolution imaging confirmed the intact crystalline structure and identified an AB stacking for gCN layers. The charge allows deliberate organic functionalisation of dissolved gCN, providing a general route to adjust their properties.
Design and synthesis of two armed molecular receptor for recognition of Gd3+ metal ion and its computational study
Authors: Mohan Brij , Modi Krunal , Patel Chirag , Bhatia Pankaj , Kumar Ashwani , Sharma Harish Kumar 
Published: August 2018

New receptor Phenylene‐Bis‐Methylfuran‐yl‐2‐Methyele Acetohydrazide (PBMMA) has been synthesized by condensation of hydrazide and 5‐methyl furfural. Synthesized receptor has been fully characterized by IR, 1H NMR, 13C NMR, mass spectroscopic and thermo gravimetric analysis. The receptor PBMMA shows selective recognition potential towards Gd3+ ion when tested with several metal ions such as Na+, K+, Mg2+, Cu2+, Cd2+, Hg2+, Y3+, La3+, Eu3+, Sm3+, Gd3+, Re6+ and Th4+ ion as their sulfates by UV–visible and fluorescence spectroscopic studies. Binding nature of PBMMA with Gd3+ ion was further studied by mass spectroscopic and cyclic voltammetric studies. The stoichiometry of PBMMA‐Gd3+ ion has been established, 1:1 by Benesi‐Hildebrand plot method and method of continuous variation (Job's plot) with association affinity K = 6.491 × 104 M−1. In addition to these, molecular docking, molecular dynamic stimulation and binding energy of complex; through Density Function theory −595.66 kcal/mol has also indication of strong binding. The electron transfer energy of Higher occupied molecular orbital (HOMO) to Lower unoccupied molecular orbital (LUMO) is about 4.186 eV and 295 nm for PBMMA‐Gd3+ Complex.
Transformative mobilities in the Pacific: Promoting adaptation and development in a changing climate
Authors: Farbotko Carol , McMichael Celia , Dun Olivia , Ransan‐Cooper Hedda , McNamara Karen E. , Thornton Fanny 
Published: August 2018

AbstractClimate change is affecting Pacific life in significant and complex ways. Human mobility is shaped by climate change and is increasingly positioned by international agencies, policymakers, and governments as having an important role in both climate change adaptation and human development. We consider the potential for human mobility to promote adaptation and development among Pacific people in a changing climate. We argue that where Pacific people choose mobility, this should be supported and create opportunities that are responsive to the histories and existing patterns of mobility and place attachment among Pacific Islanders; commence from a position of climate and development justice; and advance human rights and socio‐political equity. Transformative mobilities are where mobility, adaptation, and development intersect to achieve the best possible outcomes for cultural identity, human rights, adaptation, and human development goals across scales and in origin and destination sites.
High‐Performance Magnetic Refrigerant Featuring One‐Dimensional Gd‐O Chains and O‐Gd3 Triangles
Authors: Tao Ce , Li Rukang 
Published: August 2018

AbstractMagnetic cooling at low temperature has attracted intensive interest in cryogenics research, which may become important as cooling medium for long‐wave photon detectors to support space exploration. Here, we report a Gd‐based quaternary magnetic refrigerant material, Gd5BSi2O13, containing chains of face‐shared GdO9 polyhedra and geometrically frustrated OGd3 triangles. Magnetic measurements indicate that Gd5BSi2O13 exhibits a large magnetocaloric effect (MCE) about 1.74 times that of the practical magnetic refrigerant GGG (−ΔSm=67.0 J kg−1 K−1). We analyzed the origin of the large MCE by comparing GdIII‐containing compounds with different structures and concentrations of GdIII.
Most calbindin‐immunoreactive neurons, but few calretinin‐immunoreactive neurons, express the m1 acetylcholine receptor in the middle temporal visual area of the macaque monkey
Authors: Coppola Jennifer J. , Disney Anita A. 
Published: August 2018

AbstractIntroductionRelease of the neuromodulator acetylcholine into cortical circuits supports cognition, although its precise role and mechanisms of action are not well understood. Little is known about functional differences in cholinergic modulatory effects across cortical model systems, but anatomical evidence suggests that such differences likely exist because, for example, the expression of cholinergic receptors differs profoundly both within and between species.MethodsIn the primary visual cortex (V1) of macaque monkeys, cholinergic receptors are strongly expressed by inhibitory interneurons. Using dual‐immunofluorescence confocal microscopy, we examine m1 muscarinic acetylcholine receptor expression by two subclasses of inhibitory interneurons—identified by their expression of the calcium‐binding proteins calbindin and calretinin—in the middle temporal extrastriate area (MT) of the macaque.Results and ConclusionsWe find that the majority of calbindin‐immunoreactive neurons (55%) and only few calretinin‐immunoreactive neurons (10%) express the m1 acetylcholine receptor. These results differ from the pattern observed in V1 of the same species, lending further support to the notion that cholinergic modulation in the cortex is tuned such that different cortical compartments will respond to acetylcholine release in different ways.
Detecting peripersonal space: The promising role of ultrasonics
Authors: Chillura Antonino , Naro Antonino , Ciappina Fabrizio , Bramanti Alessia , Lauria Paola , Bramanti Placido , Calabrò Rocco Salvatore 
Published: August 2018

AbstractIntroductionThe approach of an external stimulus to the peripersonal space (PPS) modifies some physiological measures, including the cerebral blood flow (CBF) in the supplementary motor area and premotor cortex. CBF measurement may be useful to assess brain activations when producing specific motor responses, likely mediated by cortical and subcortical neural circuits.MethodsThis study investigated PPS in 15 healthy humans by characterizing the hemodynamic responses (pulsatility index, PI; and heart rate, HR) related to different directions of movements of individual's hand toward and backward his/her own face, so to perturb PPS).ResultsWe observed that the CBF and HR were enhanced more when the stimulated hand was inside the PPS of the face in the passive and active condition than when the hand was outside the PPS and during motor imagery task.ConclusionsThese results suggest that the modulation of PPS‐related brain responses depends on specific sensory‐motor integration processes related to the location and the final position of a target in the PPS. We may thus propose TCD as a rapid and easy approach to get information concerning brain responses related to stimuli approaching the PPS. Understanding the modulations of brain activations during tasks targeting PPS can help to understand the results of psychophysical and behavioral trials and to plan patient‐tailored cognitive rehabilitative training.
Crystal Structure of PigA: A Prolyl Thioester‐Oxidizing Enzyme in Prodigiosin Biosynthesis
Authors: Lee Cheng‐Chung , Ko Tzu‐Ping , Chen Chun‐Ting , Chan Yueh‐Te , Lo Shin‐Yi , Chang Jen‐Yu , Chen Ya‐Wen , Chung Ting‐Fang , Hsieh Hsin‐Ju , Hsiao Chwan‐Deng , Wang Andrew H.‐J. 
Published: August 2018

AbstractProdigiosin is an intensely red pigment comprising three pyrroles. The biosynthetic pathway includes a two‐step proline oxidation catalyzed by phosphatidylinositol N‐acetylglucosaminyltransferase subunit A (PigA), with flavin adenine dinucleotide (FAD) as its cofactor. The enzyme is crystallized in the apo form and in complex with FAD and proline. As an acyl coenzyme A dehydrogenase (ACAD) family member, the protein folds into a β‐sheet flanked by two α‐helical domains. PigA forms a tetramer, which is consistent with analytical ultracentrifugation results. FAD binds to PigA in a similar way to that in the other enzymes of the ACAD family. The variable conformations of loop β4–β5 and helix αG correlate well with the structural flexibility required for substrate entrance to the Re side of FAD. Modeling with PigG, the acyl carrier protein, suggests a reasonable mode of interaction with PigA. The structure helps to explain the proline oxidation mechanism, in which Glu244 plays a central role by abstracting the substrate protons. It also reveals a plausible pocket for oxygen binding to the Si side of FAD.
The role of the long non‐coding RNA HOXA11‐AS in promoting proliferation and metastasis of malignant tumors
Authors: Lu Shounan , Jiang Xingming , Su Zhilei , Cui Zhankun , Fu Wen , Tai Sheng 
Published: August 2018

AbstractLong non‐coding RNA (lncRNA) is one of the focuses and hotspots of biological research in recent years. At the same time, tumors have become the main disease that endangers human health. In recent years, a large number of researchers have explored the relationship between lncRNA and tumors. HOXA11‐AS is one of these lncRNAs. The long non‐coding RNA HOXA11 antisense RNA (HOXA11‐AS) is a novel lncRNA recently discovered. It is found in a variety of tumors such as ovarian cancer, glioma, and gastric cancer (GC) and so on, and is defined as an oncogene. It promotes tumor proliferation and metastasis by interacting with proteins such as miRNA and EZH2. In this paper, we review the mechanism of interaction between HOXA11‐AS and various tumors in recent years, and believe that it can be a potential tumor marker and therapeutic target in the future prevention and treatment of tumors.
miR‐185 affected the EMT, cell viability, and proliferation via DNMT1/MEG3 pathway in TGF‐β1‐induced renal fibrosis
Authors: Xue Rong , Li Yingping , Li Xiaoli , Ma Jingang , An Caiping , Ma Zhigang 
Published: August 2018

AbstractKidney fibrosis is usually the final manifestation of a wide variety of renal diseases. Recent years, research reported that long non‐coding RNAs (lncRNAs) played important roles in a variety of human diseases. However, the role and underlying mechanisms of lncRNAs in kidney fibrosis were complicated and largely unclear. In our study, we constructed the cell model of renal fibrosis in HK2 cells using transforming growth factor β1 (TGF‐β1) and found that lncRNA maternally expressed gene 3 (MEG3) was downregulated in TGF‐β1‐induced renal fibrosis. We then found that overexpressed MEG3 inhibited the TGF‐β1‐induced promotion of epithelial–mesenchymal transition, cell viability, and proliferation. Furthermore, we demonstrated that DNA methyltransferases 1 (DNMT1) regulated the MEG3 expression by altering the CpGs methylation level of MEG3 promoter in TGF‐β1‐induced renal fibrosis. In addition, we further revealed that miR‐185 could regulate the DNMT1 expression and thus, modulate the MEG3 in TGF‐β1‐induced renal fibrosis. Ultimately, our study illustrated that the modulation of the miR‐185/ DNMT1/ MEG3 pathway exerted important roles in TGF‐β1‐induced renal fibrosis. In summary, our finding displayed a novel regulatory mechanism for TGF‐β1‐induced renal fibrosis, which provided a new potential therapeutic target for renal fibrosis.
Facile Fabrication of Ultrasmall Copper Species Confined in Mesoporous Silica for Chemo‐Selective and Stable Hydrogenation Ethylene Carbonate Derived from CO2
Authors: Zhang Chanjuan , Wang Liguo , Liu Jiaju , Yang Yanmi , He Peng , Cao Yan , Chen Jiaqiang , Li Huiquan 
Published: August 2018

AbstractThe hydrogenation of ethylene carbonate to co‐produce commodity methanol and ethylene glycol has attracted growing interests due to the potential chemical utilization of CO2 in large scale. In this work, we report a novel and facile protocol for the preparation of mesoporous Cu@SiO2 catalysts and successfully applied the as‐synthesized catalysts in the hydrogenation of ethylene carbonate. The catalysts were characterized in detail by means of N2 physisorption, N2O titration, XRD, FT‐IR, H2‐TPR, TEM and XPS (XAES). This strategy is an effective method for fabricating the unique flower‐like mesoporous Cu@SiO2 with sub‐2.0 nm ultrasmall Cu particles. The results revealed that the involvement of β‐cyclodextrin improved the Cu dispersion and facilitated exposing more copper active sites, which also indicated that the confined catalyst inhibiting the sintering of copper particles. Meanwhile, the stability of the attained catalyst was superior with the modification of carbon. Importantly, among the catalysts tested in the hydrogenation of ethylene carbonate, 25Cu@SiO2‐β‐P with appropriate copper loading as well as moderate Cu+ ratio exhibited superior catalytic performance. Accordingly, the synergistic effect between the Cu+ and metallic Cu0 species was crucial for obtaining better catalytic activity.