bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinetics of Symmetrical Versus Asymmetrical In‐Phase Gaits During Arboreal Locomotion
Authors: Lammers Andrew R. , Stakes Sarah A. 
Published: October 2024

ABSTRACTQuadrupedal animals traveling on arboreal supports change aspects of locomotion to avoid slipping and falls. This study compares locomotor biomechanics in two small mammals: first, the gray short‐tailed opossum (Monodelphis domestica) predominantly trots, which is a symmetrical gait. The second species, the Siberian chipmunk (Tamias sibiricus), primarily bounds or half‐bounds. Trotting and bounding differ fundamentally in three aspects: location and timing of hand and foot placement; in the way that the trunk bends (trotting, mediolateral bending; bounding, flexion, and extension); and in the dynamics of the center of mass. Both species ran on a flat track and a 2 cm diameter cylindrical track, instrumented with a force plate or pole. For bounding chipmunks, the force pole was modified to measure force only on the right side. We measured speed, duty factor, and force, and calculated vertical, braking, propulsive, and net mediolateral impulses. Vertical and fore‐aft impulses were different between trotting opossums and bounding chipmunks, but between trackway types, these impulses were similar within each species. The modifications used by each species to travel on arboreal supports were similar, except in one important respect. Net mediolateral impulse in opossums changed from laterally directed on the flat trackway to medial on the arboreal. But in chipmunks, these impulses on the flat track were medially‐directed, and on the arboreal track, the amount of variability was substantially greater. We conclude that chipmunks—and perhaps any bounding animal—are less consistent from stride to stride in their locomotion. This inconsistency requires constant medial and lateral impulses to correct their trajectory when traveling on arboreal surfaces.
The role of resilience in navigating work stress and achieving daily work goals
Authors: Zhu Ze , Hu Xinyu , Zhang Bo 
Published: October 2024

SummaryOn a daily basis, resilience is critical for employees to cope with difficulties and challenges in achieving work goals. Understanding the dynamic resilience process throughout the workday is crucial for gaining insights into how employees can effectively leverage their resilience to meet their daily work goals. The present study aims to examine this dynamic resilience process in response to work stress while pursuing work goals among employees with different levels of trait resilience. Drawing on resilience literature and the conservation of resources theory, we propose a resilience‐depleting process in response to morning work stress within a short, half‐day timeframe. We further examine whether state resilience impacts subsequent work goal striving at the within‐person level. Additionally, we explore the buffering effect of trait resilience on the resilience‐depleting process after experiencing work stress. To test our hypotheses, we employed the experience sampling methodology with 108 full‐time employees over five consecutive workdays. Multilevel analyses revealed that morning work stress significantly diminished state resilience, indirectly influencing daily work goal progress through work goal activation. Notably, trait resilience buffered the negative impact of work stress on state resilience. These results offer insights into theoretical understanding and practical implications for managing employee state resilience in the face of work stress to achieve daily work goals.
Hormone Receptor Positive Breast Cancer in Young Women: A Review
Authors: McShane Nicola , Zaborowski Alexandra , O'Reilly Mary , McCartan Damian , Prichard Ruth 
Published: October 2024

ABSTRACTThe global incidence of hormone‐positive breast cancer (HR+ BC) in young women is rising, though the underlying reasons remain unclear. HR+ disease in younger women appears to represent a distinct clinical entity compared to that in older women, exhibiting distinct clinicopathological characteristics, outcomes and responses to treatment. Despite these differences, there is a paucity of large‐volume data focusing on young women with HR+ in contemporary literature. Hormone receptor positive breast cancer in young women is associated with poorer prognoses compared to older women. Additionally, early age onset breast cancer presents unique challenges, including concerns related to fertility, the toxic effects of therapeutic agents, and specific surgical considerations. The purpose of this review is to report the existing literature on HR+ disease in young women.
Clinical spectrum of indolent mycosis fungoides with a gamma‐delta (γδ) phenotype: a single institution review including therapy and outcomes
Authors: Ufkes N. A. , Tao R. , Halwani A. S. , Miles R. , Cipriano S. D. , Bowling M. , Florell S. , Gaffney D. , Wada D. A. 
Published: October 2024

AbstractBackgroundPrimary cutaneous γδ T‐cell lymphoma (CGD‐CTL) is a rare malignancy that classically exhibits an aggressive clinical phenotype.ObjectivesReview cases of mycosis fungoides with a γδ phenotype that demonstrated an indolent clinical course.MethodsRetrospective review of patients diagnosed with MF with a γδ phenotype and an indolent clinical course between 2018 and 2022 treated at the University of Utah.ResultsFive patients ages 4‐81 years old were identified. All presented with clinically persistent patch or plaque‐stage disease, and histopathology showed primarily epidermotropic infiltrates positive for TCR delta via immunostaining. None of these patients have required aggressive treatment with multiagent chemotherapy.ConclusionsThere exists a subset of indolent CGD‐TCL patients who are clinicopathologically distinct from classic CGD‐CTL and clinically resembling indolent MF. Therefore, we prefer the term “MF with γδ phenotype” for these rare cases.
How Knowledge Spillover Entrepreneurship Influences the Adoption of Social Media and Customer Relationship Management
Authors: Qalati Sikandar Ali , Tajeddini Kayhan , Gamage Thilini Chathurika 
Published: October 2024

ABSTRACTBased on the knowledge‐based view, this paper investigates how the strategic integration of knowledge spillover through entrepreneurial orientation (EO), adoption of social media (SM) and customer relationship management (CRM), and environmental turbulence collectively manage to enhance firm performance in developing economies. To test these assertions, we surveyed managers from 519 randomly selected firms in China, and data were analyzed using SmartPLS 4.0. The results reflect that knowledge spillover through EO significantly enhances firm performance. In contrast, knowledge spillover through adopting SM mediates the relationship between EO and firm performance, whereas environmental turbulence and CRM moderate the relationship between adopting SM and firm performance. These findings enrich knowledge management literature from theoretical and managerial perspectives.
Accelerated Decline in Vegetation Resilience on the Tibetan Plateau
Authors: Liu Yantao , Xiao Pengfeng , Zhang Xueliang , Liu Hao , Chen Siyong , Jia Yumeng 
Published: October 2024

ABSTRACTThe ability of ecosystems to resist and recover from external disturbances is declining due to climate change, increased frequency of disasters, and intensified human activities. Global vegetation resilience is considered to be at risk of being lost. The sensitive and fragile Tibetan Plateau (TP) has experienced changes in climate and management patterns over the past five decades, but due to the complexity of defining resilience, there is still no unified understanding of the spatial patterns and long time‐series trends of resilience on the TP. In this study, we introduce the method based on critical slowing down, making it possible to clarify the spatial distribution and temporal dynamics of resilience on the TP. The results show low resilience on the northeastern and southwestern edges of the TP and in the Three River Source region. The area experiencing resilience loss is approximately 1.16–1.44 times larger than the area of gain. Vegetation resilience on the TP has exhibited a declining trend, with the rate of decline after 2014 being more than double that of the preceding period. Factors such as elevation, vegetation type, and hydrothermal condition significantly influence the spatial and temporal patterns of resilience. These findings improve our understanding of vegetation resilience on the TP and its ecosystem vulnerability. We also recommend that ecological restoration efforts be maintained and regularly assessed.
Fundamental problems in the peer‐review process and stakeholders' perceptions of potential suggestions for improvement
Authors: Kadaifci Cigdem , Isikli Erkan , Topcu Y. Ilker 
Published: October 2024

AbstractAcademic papers are essential for researchers to communicate their work to their peers and industry experts. Quality research is published in prestigious scientific journals, and is considered as part of the hiring and promotion criteria at leading universities. Scientific journals conduct impartial and anonymous peer reviews of submitted manuscripts; however, individuals involved in this process may encounter issues related to the duration, impartiality, and transparency of these reviews. To explore these concerns, we created a questionnaire based on a comprehensive review of related literature and expert opinions, which was distributed to all stakeholders (authors, reviewers, and editors) who participated in the peer‐review process from a variety of countries and disciplines. Their opinions on the primary issues during the process and suggestions for improvement were collected. The data were then analysed based on various groups, such as gender, country of residence, and contribution type, using appropriate multivariate statistical techniques to determine the perceptions and experiences of participants in the peer‐review process. The results showed that unethical behaviour was not uncommon and that editors and experienced reviewers encountered it more frequently. Women and academics from Türkiye were more likely to experience ethical violations and perceived them as more ethically severe. Incentives and stakeholder involvement were seen as ways to enhance the quality and impartiality of peer review. The scale developed can serve as a useful tool for addressing difficulties in the peer‐review process and improving its effectiveness and performance.
Social dynamics of luxury customization: The unique impact of name personalization
Authors: O'Rourke Anne‐Maree , Lin Joanna , Sung Billy , Septianto Felix 
Published: October 2024

AbstractAs customized luxury becomes increasingly mainstream, adhering to a uniform treatment of all types of customization falls short of the nuanced insight needed. Our research focuses on the effects of a prevalent form of customization—name personalization—on the perceived “social cost” associated with luxury items from a potential buyer's point of view. Despite most luxury brands offering consumers the option to imprint their names on products for a personalized touch, concerns arise about being perceived to be “showing off.” Our four experimental studies demonstrate that adding one's name to luxury goods heightens apprehensions about the social cost, specifically diminishing metaperceptions of warmth due to impression management (Study 1). This phenomenon applies to both the imprinting of one's full first name, and only their initials (Study 2). However, luxury consumers with a lower social‐adjustive (i.e., less driven by the desire for social approval) show an elevated concern over the social cost of name personalization (Studies 3 and 4). As the trend of customizing luxury items rises, our findings emphasize the significance of luxury researchers and practitioners to discern both the positive and negative outcomes associated with various forms of luxury customization.
Facile and Efficient Synthesis of Fluorosilicone Polymers by Using an Optimized Gradient Ring‐Opening Reaction
Authors: Li Jing‐Yang , Pan Hong‐Tao , Yang Fan , Wu Yu‐Yue , Wu Bin‐Bin , Song Jiang , Li Yang , Zhang Guo‐Dong , Tang Long‐Cheng 
Published: October 2024

AbstractFluorosilicone rubber is essential for sealing in extreme temperatures and non‐polar environments due to its exceptional adaptability. However, achieving a high yield of fluorosilicone polymers with medium and high fluorine content remains a challenge. Herein, a facile gradient strategy is developed that involves modifying the method of cyclic monomer addition based on the rate of ring‐opening polymerization (ROP), to improve yield and adjust fluorine content precisely. The polymerization process is designed and tailored based on the reaction rates of anionic ring‐opening polymerization (AROP) and cationic ring‐opening polymerization (CROP) via an efficient gradient strategy. The effects of the polymerization process on the viscosity and yield of vinyl fluorosilicone polymers and hydrofluorosilicone polymers are investigated and optimized. Notably, the as‐prepared vinyl‐terminated fluoromethylsilane with 60% fluorine content (FMS‐Vi‐60F) has a high yield (86.6%) and high viscosity (150 000 mPa·s) in a short reaction time, which is superior to previous methods. Clearly, the gradient ring‐opening method developed in this work provides a facile and efficient synthesis for fabricating fluorosilicone polymers with a high yield and tunable fluorine content.
N6‐methyladenosine reader YTHDF3‐mediated zinc finger protein 41 inhibits hepatocellular carcinoma progression by transcriptional repression of Snail
Authors: Li Xinxin , Han Mengzhen , Zhu He , Zhang Hongwei , Pan Yonglong , Liang Huifang , Liao Zhibin , Zhang Bixiang , Chen Xiaoping 
Published: October 2024

AbstractAdvanced metastasis of hepatocellular carcinoma (HCC) significantly contributes to high death rates among patients. The efficiency of targeted therapies and chemotherapeutic agents shows individual variability. Therefore, there is no effective treatment for advanced HCC. Zinc finger proteins (ZFPs) are known to be crucial in various tumors, especially on HCC. In our study, we verified that ZFP41 could suppress the progression and metastasis of HCC through in vitro and in vivo experiments. During the past years, N6‐methyladenine (m6A) regulation has also been increasingly reported in HCC. To investigate whether ZFP41 could be regulated via m6A methylation, our results showed that YTHDF3 bound to the mRNA of ZFP41 and degrade it. Subsequently, to further elucidate the function of ZFP41, we identified Snail, a well‐known oncogenic molecule, through RNA‐seq. As a canonical component in the epithelial‐to‐mesenchymal transition (EMT) pathway, Snail plays a pivotal role and is a critical marker for tumor invasion and metastasis. Our results showed ZFP41 could inhibit Snail and the EMT pathway through its transcriptional repression. In conclusion, our study revealed that ZFP41 is a potential prognostic element for patients with HCC, and targeting ZFP41 might be used for translational clinical applications as a promising therapeutic target.
Research on Knowledge Payment Product Supply Chain Governance Based on Blockchain: An Evolutionary Game Model
Authors: Liu Lili , Luo Changxin 
Published: October 2024

ABSTRACTBlockchain provides a new opportunity to govern the dilemmas in the knowledge payment product supply chain. This paper introduces blockchain into the evolutionary game to explore the behavioral strategies of knowledge providers, platforms, and consumers and to analyze in depth the influence of initial willingness and blockchain‐related factors by the system dynamics. The analysis shows that (1) improving the tripartite initial willingness is conducive to accelerating the process of supply chain governance and making the system reach an ideal state: knowledge providers choose compliance creation, platforms adopt blockchain, and consumers buy authorized product; (2) there are specific thresholds for the blockchain adoption cost and the premium of product brought by blockchain, only when the cost and premium are lower than the thresholds, the system evolves towards the ideal state; (3) when blockchain is adopted, it can effectively inhibit knowledge providers' illegal creation behavior and consumers' piracy behavior by increasing the punishments of platforms on knowledge providers and consumers. The results provide guidance to implement effective governance and the orderly development of knowledge payment industry.
Object Localization in Highly Cluttered Environments Using Neural Network Learning on Microwave Scattering Data
Authors: Jeong Janghoon , Park Won‐Kwang , Son Seong‐Ho 
Published: October 2024

ABSTRACTBifocusing‐based microwave imaging is a promising direct imaging method for object localization in various applications. However, the method has the limitation that it only works well in environments with a homogenous background. In this paper, we present a direct microwave imaging method using a neural network (NN) model that can localize a small object even in highly cluttered environments with strong scatterers. The NN model is trained on some data sets obtained through multistatic measurements in a nonhomogeneous environment. To verify the approach, we prepared an experimental testbed equipped with a water tank containing 3 strong scatterers and 16 antennas to obtain 920 MHz multistatic scattering data. This experiment shows good localization performance, with an average localization error of approximately 4 mm (1/9 of a wavelength) over the entire experimental area, even in a strong scattering background.
In‐line spectroscopy for iodine quantification in dynamic contrast‐enhanced dedicated breast CT
Authors: Goris Liselot C. , Mikerov Mikhail , Pautasso Juan J. , Sechopoulos Ioannis 
Published: October 2024

AbstractBackgroundIn 4D dynamic contrast‐enhanced dedicated breast computed tomography (4D DCE‐bCT), the functional properties of the breast will be characterized by monitoring the uptake and washout of iodine‐based contrast agents over time. This information could be valuable in breast cancer treatment. However, prior to clinical implementation, it is crucial to validate the quantitative estimates of iodine concentrations at each time point during acquisition.PurposeTo develop an in‐line spectroscopy system capable of measuring iodine concentrations in a dynamic x‐ray breast phantom in real‐time.MethodsPotassium iodide served as the contrast agent. The system was set‐up at both the entrance and exit of the phantom. It comprises a fiber‐coupled green LED and collimator, which together ensure that a parallel beam passes through the sample holder. Transmitted light is captured by a collimator on the opposite side and directed through a fiber optic cable to a photodetector for intensity measurement. The relationship between 13 iodine concentrations (0–6 mg I/mL) and light transmission was tested, and the system's repeatability and accuracy were determined.ResultsThe system exhibited a strong correlation between iodine concentration and transmission values, achieving a root‐mean‐square error of 0.007. The repeated measurements had relative standard deviations of 0.04% and 0.1% for repeated water measurements at the phantom's entrance and exit, respectively. Furthermore, the accuracy measurements gave a mean error of fitting of 0.008 (± 0.07) mg I/mL.ConclusionThe in‐line spectroscopy system can effectively monitor iodine concentrations in a dynamic breast phantom, providing a reliable method for quantitative validation of 4D DCE‐bCT.
Safety and Efficacy of Trospium Chloride and Solifenacin in Stroke‐Induced Neurogenic Lower Urinary Tract Dysfunction: A Randomized Controlled Trial
Authors: Hajebrahimi Sakineh , Pourmohammad Ali , Konstantinidis Charalampos , Samarinas Michael , Morsali Soroush , Mostafaei Hadi , Farhoudi Mehdi , Rahnama'i Mohammad‐Sajjad , Beheshti Rasa , Salehi‐Pourmehr Hanieh 
Published: October 2024

ABSTRACTBackgroundNeurogenic dysfunction of the lower urinary tract is one of the challenging diseases with high burdens in urology. Our study aims to evaluate the efficacy of a 4‐week treatment with Solifenacin and Trospium chloride and assess their safety and impact on quality of life.MethodsFollowing the selection of 206 stroke patients from two centers who met specific eligibility criteria, including a clinical diagnosis of stroke, normal cognitive function, and the presence of lower urinary tract symptoms (LUTS), participants were randomly assigned to receive oral Solifenacin, Trospium chloride, or a placebo. Under the supervision of the Ethics Committee, the baseline characteristics, compliance with medication, and outcomes were monitored, gathered, and analyzed.ResultsThe majority of participants were male, with a mean age of 67.3, and most had ischemic stroke. The groups had no significant difference in urinary symptoms after stroke. All of the symptoms in the study groups, according to the NBSS questionnaire, were decreased following treatment compared to the baseline (p < 0.05). After treatment, ICIQ‐OAB, and ICIQ‐LUTS‐QOL total scores and bothersome scores decreased significantly compared to baseline (p < 0.001). When compared to the placebo, both Trospium chloride and Solifenacin alleviated symptoms according to the NBSS questionnaire and ICIQ‐LUTS‐QOL, total ICIQ‐OAB, and the total score of ICIQ‐OAB‐Bothersome. However, the total LUTS‐QOL‐Bothersome score did not change in the active treatment groups compared to the placebo. While comparing the two drugs, these values were similar except for the total score of LUTS‐QOL‐Bothersome, ICIQ‐OAB, and ICIQ‐OAB‐Bothersome in favor of the Solifenacin group. Moreover, Solifenacin had fewer side effects compared to Trospium chloride or placebo.ConclusionThe study analyzed 206 stroke patients in two international centers and found both drug arms effective in treating overactive bladder. However, inconsistencies were found in efficacy and safety, necessitating further studies with larger populations.Trial RegistrationThis triple‐blind, multicenter, randomized controlled trial was done on 206 stroke patients after getting Ethical Committee approval and registering the project on IRCT (IRCT20160606028304N2).