bluuebunny/crossref_metadata_2025_split huggingface dataset:
Awareness and Adoption of Quick Response Code by Librarians in Universities in Delta and Edo States, Nigeria
Authors: Esoswo  Ogbomo Francisca , Irogbo Ishioma Faith 
Published: November 2024

Rationale of Study – Quick response code is a barcode that stores readable information using a digital device. They track information about products frequently used in marketing and advertising campaigns. The study investigated librarians’ awareness and adoption of quick response codes in universities in Delta and Edo states, Nigeria. Methodology – A descriptive survey design was employed to establish the relationship between librarians’ awareness and the willingness to adopt QR codes using a population of 124 librarians from 14 libraries in Delta and Edo states, Nigeria. Frequencies were used to analyse the respondents' demographic information, and the statistical mean (x) was used to answer the research questions. The criterion mean was placed at 2.50. Findings – Findings revealed that many librarians in Delta and Edo States university libraries are familiar with QR codes. Librarians are willing to use QR codes to market services to users, connect users directly to online resources, and create codes for all primary library services to users. There is a significant relationship between librarians' awareness and their willingness to adopt QR codes in university libraries in Delta and Edo states. Implications – The study recommended that more awareness campaigns be organized to attract more librarians to QR codes. Originality – This is original research conducted to ascertain the level of awareness and adoption of quick response codes by librarians in university libraries in Delta and Edo states, Nigeria.
Human Factors Affecting the Preservation of Serial Materials: A Case Study of Federal University Libraries in North Central Nigeria
Authors: Monday Obaidjevwe Ogbomo , Efe Francis Ejedafiru , Olukotun, Victor Olukotun, Victor 
Published: November 2024

Rationale of Study – This study examined the human factors that affected the preservation of serial materials in federal university libraries in north-central Nigeria. The objective was to analyse human factors influencing the preservation of serial collections in federal university libraries. Methodology – The study used a descriptive research design. The population was 250 librarians, while 196 was used as the sample. A self-created open-ended questionnaire collected responses from librarians and library officers at federal university libraries in north-central Nigeria. Findings – The study revealed that human factors, such as theft and vandalism, natural disasters, and rough treatment of serial items, impact the preservation of these resources. The libraries use various preservation techniques, including dust removal, laminating, shelf care, repairing faded inks, binding, and photocopying. The statistically significant influence of human variables on preserving serial materials in federal university libraries in central Nigeria was also made clear. Librarians in these libraries had implemented some preservation strategies due to the deteriorating nature of serial material and the associated effects of human factors. Implications – It was suggested, among other things, that university library management regularly teach library employees to incorporate more preservation techniques for serial items, like bleaching and pesticide use, microfilming, de acidification, and digitisation. Originality – This paper publishes the results of an original study on the human factors which affect the preservation of serials in federal libraries in Nigeria.
Effects of Hypogonadism and Testosterone Therapy on Diabetic Foot Complications
Authors: Jupiter Daniel C. , Faaitiiti Kelli L. , Rodriguez Robert A. , Polychronopoulou Efstathia , Lopez David S. 
Published: November 2024

Background: Results of recent studies suggest that high levels of endogenous testosterone decrease the risk of diabetes. Testosterone therapy may delay the transition from prediabetes to diabetes and accelerate healing of diabetic foot ulcers in hypogonadal men. We investigated whether testosterone therapy in this population decreases the occurrence of diabetic foot complications within 1 and 5 years of diabetes diagnosis.
Methods: Optum’s deidentified Clinformatics Data Mart database was searched for male patients with diabetes. Associations between testosterone therapy and the occurrence of ulceration or the use of wound care were explored in the entire population and in those with and without hypogonadism using both bivariate and multivariate analyses.
Results: Contrary to the hypotheses, testosterone therapy seems to confer increased risk of diabetic foot complications. In hypogonadal men with at least 1 year of follow-up after diabetes diagnosis, any use of testosterone therapy increased the odds of wound care utilization by a factor of 1.10 (95% confidence interval, 1.03–1.17), and the odds of ulceration by a factor of 1.13 (95% confidence interval, 1.03–1.24). Similar results are seen in all men, both with and without hypogonadism. Further exploration reveals that hypogonadism also increases the risk of wounds among people with diabetes with care utilization in the entire population.
Conclusions: Further research is needed to elucidate the mechanisms by which hypogonadism and testosterone therapy impact diabetic foot complications, and whether these mechanisms are mediated by vascular or neurologic factors.
How Canines Can Assist Our Patients with Diabetes: Diabetes Alert Dogs: What Are Their Capabilities?
Authors: Jenkins David W. , Thompson Kaitlin M. , Goeddeke Nikki 
Published: November 2024

Background: The canine olfactory system is used for tasks that greatly aid society, such as detecting explosives, finding lost persons, and detecting many diseases and abnormal blood sugar levels early. However, the reliability of detection of glycemic fluctuations is questionable.
Methods: We reviewed the literature on the capability of canines in detecting significant variations in blood sugar. Traditional studies and anecdotal reports were assessed. Articles and resources that outline the available training and certification process were included.
Results: Publications included studies of canines’ ability to detect scents associated with hyperglycemia and hypoglycemia as well as behavioral changes associated with blood sugar abnormalities. Several anecdotal reports denoted excellent canine performance in detection. Perusal of literature and Web-based resources found a range of available training, from formal (with certification) to do-it-yourself home training. Evidence supporting improved mental/physical health in persons using service dogs was robust.
Conclusions: Canines have the capability to detect numerous medical conditions, including dangerous fluctuations in blood sugar in persons with diabetes, especially hypoglycemia. Most studies on the reliability and performance of diabetes alert dogs report potential lifesaving benefits but demonstrate notable variability and inconsistencies, which may be due to lack of required formal training or a certification process. Most owners believe their dogs are highly effective and greatly improve their life and safety. Due to the improving technology seen with continuous glucose monitoring devices, many believe diabetes alert dogs will become obsolete. Aside from an early warning system, diabetes alert dogs can play a significant role in overall quality of life, especially in benefiting physical and mental health.
Developing a Podiatric Telemedicine Framework for Service Users and Providers in a Primary-Care Setting
Authors: Mercieca Lisa Ann Stojmanovski , Formosa Cynthia , Chockalingam Nachiappan 
Published: November 2024

Background: The use of telemedicine has garnered significant traction amidst the COVID-19 pandemic. The sudden adoption of certain practices in podiatry was not always supported by empirical evidence, resulting in the development of guidelines and metrics that lacked a foundation in rigorous research.
Methods: A modified Delphi composed of three rounds was conducted with 16 stakeholders (service users, foot and ankle health-care providers, and policymakers) from a primary-care setting to develop a podiatric telemedicine framework for a primary-care setting. The first round consisted of focus group discussions, the second round consisted of a questionnaire composed of different statements that emerged from focus group discussions, and the final third round consisted of a questionnaire with statements from the second round that required further reiterations. Statements that achieved an 80% or higher level of agreement were accepted to form part of the podiatric telemedicine framework.
Results: Excellent consensus data was obtained to develop the podiatric telemedicine framework. Although podiatric telemedicine for low-risk patients in a primary-care setting is relatively new, stakeholders highlighted the importance of having podiatric telemedicine guidelines and setting service user and provider expectations clear on what podiatric telemedicine has to offer and its pitfalls.
Conclusions: The podiatric telemedicine framework developed is recommended to all foot and ankle health-care professionals in a primary-care setting who wish to provide telemedicine consultations. Moreover, it is recommended that a pilot study be carried out to look into the feasibility of this framework being translated and implemented as a guideline related to foot and ankle telemedicine consultations.
Comparative electromyography analysis of subphase gait disorder in chronic stroke survivors
Authors: Hohsoh Nusreena , Sanghan Thanita , Chong Desmond Y.R. , Stojanovic Goran , Chatpun Surapong 
Published: November 2024

Abnormal lower limb muscle activity is the most common cause of the alterative pattern of gait in stroke survivors, resulting from spastic and paralytic muscles around the hip, knee, and ankle joints. However, the activity of the major lower limb muscles that control the legs to facilitate walking in stroke patients have not been clearly understood in each subphase of the gait. This study differentiated the characteristics of surface electromyography (sEMG) signals of lower limb muscles during four subphases of gait cycle between stroke patients and healthy subjects. Sixteen chronic stroke patients and sixteen healthy subjects were recruited. All participants completed three walking trials with a self-selected walking speed. The sEMG signals were recorded on the gluteus medius, rectus femoris, long head of biceps femoris, medial gastrocnemius, tibialis anterior, and peroneus longus muscles. The characteristics of sEMG signals were processed and analyzed in the time and frequency features, considering the first double support, single support, second double support, and swing phases of the gait cycle.The stroke patients had altered sEMG characteristics on both paretic and non-paretic sides compared to healthy subjects across the sub-phases of gait cycle for all six muscles. All time domain features of sEMG signal showed that the medial gastrocnemius muscle has the most significant impaired activity (p < 0.05) and affected gait disturbance during all four subphases of the gait cycle. The findings demonstrated that the medial gastrocnemius muscle had impaired activity and was most affected during all four sub-phases of the gait cycle. This indicates that sEMG of medial gastrocnemius muscle can be used to measure the improvement of gait rehabilitation.
Flexible and Implantable Microelectrodes for Chronically Stable Neural Interfaces
Authors: Shi Jidong , Fang Ying 
Published: October 2018

AbstractImplantable electrical probes that can record neural activities at single‐neuron and sub‐millisecond resolution are the most widely applied tools in both neuroscience research and neuroprosthetics. However, the structural and mechanical mismatch between conventional rigid probes and neural tissues results in inflammatory responses and signal degradation over chronic recordings. Reducing the cross‐sectional footprints and rigidity of the probes can effectively improve the long‐term stability of neural interfaces. Herein, recent progress in the development of implantable microelectrodes for chronically stable neural interfaces is highlighted, with a focus on the utilization of advanced materials and structural design concepts.
Catalytic Enantioselective Aldol Reactions of Unprotected Carboxylic Acids under Phosphine Oxide Catalysis
Authors: Kotani Shunsuke , Yoshiwara Yusaku , Ogasawara Masamichi , Sugiura Masaharu , Nakajima Makoto 
Published: October 2018

AbstractThe first catalytic enantioselective aldol reaction of various unprotected carboxylic acids is described. In the presence of a chiral bis(phosphine oxide) as a Lewis base catalyst, carboxylic acids were activated with silicon tetrachloride to form the corresponding bis(trichlorosilyl)enediolates in situ, which subsequently underwent an aldol reaction with an aldehyde or a ketone to produce β‐hydroxycarboxylic acids in high enantioselectivities of up to 92 % ee.
Generation and Biological Characteristics of a Mouse Model of Breast Cancer that Copresents with Diabetes Mellitus
Authors: Li Mengshi , Cao Jinghua , He Yajun , Zhou Zijun , He Xiaodong , Zhang Qian‐Qian , Wang Li‐Jing , Qi Cui‐Ling 
Published: October 2018

ABSTRACTBoth diabetes and breast cancer are common diseases worldwide, and diabetes is also linked to higher rates of breast cancer. Epidemiological data also indicate that diabetes may be one of the risk factors for breast cancer. However, the effect of diabetes on breast cancer progression in vivo is rarely reported. We established an ideal animal model of breast cancer using transgenic MMTV‐PyMT mice, which spontaneously developed breast cancer. In this model, the animals copresented with diabetes mellitus, which allowed us to study the effect of high glucose on breast cancer. Compared with MMTV‐PyMT mice without diabetes, MMTV‐PyMT mice with diabetes developed heavier tumors and exhibited greater tumor volumes. Furthermore, high glucose promoted the invasiveness and metastasis of breast cancer in MMTV‐PyMT mice. This breast cancer model in which mice copresented with diabetes provides a useful tool to study the effect of diabetes on breast cancer. Anat Rec, 302:269–277, 2019. © 2018 Wiley Periodicals, Inc.
Arterial Patterns of the Face in Camelidamorpha
Authors: Kowalczyk Karolina , Zdun Maciej , Frąckowiak Hieronim 
Published: October 2018

ABSTRACTArteries supplying the intermandibular, mental, masseteric, buccal, labial, and nasal regions of the face in selected species belonging to the suborder Tylopoda are described in this study. Analyses were conducted on a total of five species representing the family Camelidae based on 27 heads of cadaveric specimens, which were prepared by arterial injection with acetone‐dissolved stained vinyl super chloride or stained latex LBS3060. Vascularization of regions of the face was formed by the facial, sublingual, mental, transverse facial, buccal, and infraorbital arteries. It was confirmed that the linguofacial trunk is absent in Camelidae. In turn, in camels the deep temporal artery descended in the common trunk with the transverse facial artery, while in llamas and alpacas it was a direct branch of the maxillary artery. It was shown that the pattern of facial arteries in Camelidamorpha exhibits specific traits for this clade and differs from the system of these arteries in other artiodactyls. The described specific character in arterial vascularization of the face not only expands the spectrum of morphological characteristics in Camelidae, but it also provides information which may prove useful for clinical purposes in veterinary practice. Anat Rec, 301:2122–2127, 2018. © 2018 Wiley Periodicals, Inc.
Annotating Transcriptional Effects of Genetic Variants in Disease‐Relevant Tissue: Transcriptome‐Wide Allelic Imbalance in Osteoarthritic Cartilage
Authors: den Hollander Wouter , Pulyakhina Irina , Boer Cindy , Bomer Nils , van der Breggen Ruud , Arindrarto Wibowo , Couthino de Almeida Rodrigo , Lakenberg Nico , Sentner Thom , Laros Jeroen F. J. , ‘t Hoen Peter A. C. , Slagboom Eline P. E. , Nelissen Rob G. H. H. , van Meurs Joyce , Ramos Yolande F. M. , Meulenbelt Ingrid 
Published: October 2018

ObjectiveMultiple single‐nucleotide polymorphisms (SNPs) conferring susceptibility to osteoarthritis (OA) mark imbalanced expression of positional genes in articular cartilage, reflected by unequally expressed alleles among heterozygotes (allelic imbalance [AI]). We undertook this study to explore the articular cartilage transcriptome from OA patients for AI events to identify putative disease‐driving genetic variation.MethodsAI was assessed in 42 preserved and 5 lesioned OA cartilage samples (from the Research Arthritis and Articular Cartilage study) for which RNA sequencing data were available. The count fraction of the alternative alleles among the alternative and reference alleles together (φ) was determined for heterozygous individuals. A meta‐analysis was performed to generate a meta‐φ and P value for each SNP with a false discovery rate (FDR) correction for multiple comparisons. To further validate AI events, we explored them as a function of multiple additional OA features.ResultsWe observed a total of 2,070 SNPs that consistently marked AI of 1,031 unique genes in articular cartilage. Of these genes, 49 were found to be significantly differentially expressed (fold change <0.5 or >2, FDR <0.05) between preserved and paired lesioned cartilage, and 18 had previously been reported to confer susceptibility to OA and/or related phenotypes. Moreover, we identified notable highly significant AI SNPs in the CRLF1, WWP2, and RPS3 genes that were related to multiple OA features.ConclusionWe present a framework and resulting data set for researchers in the OA research field to probe for disease‐relevant genetic variation that affects gene expression in pivotal disease‐affected tissue. This likely includes putative novel compelling OA risk genes such as CRLF1, WWP2, and RPS3.
Concept and practice of transradial 5 French percutaneous treatment of coronary bifurcation lesions
Authors: Sgueglia Gregory A. , Gioffrè Gaetano , De Santis Antonella , Piccioni Fabiana , Summaria Francesco , Di Giorgio Angela , D'Errico Fabrizio , Gaspardone Achille 
Published: October 2018

AbstractObjectivesTo assess the efficacy and safety of transradial 5 French percutaneous treatment of coronary bifurcations using conventional devices.BackgroundRadial artery is smaller than femoral artery, and its size may potentially limit transradial intervention, especially when coronary anatomy is not known.MethodsPatients with bifurcations lesions undergoing transradial 5 French ad hoc revascularization were treated according to provisional side branch (SB) stenting followed by the POT—SB dilation—final POT sequence. Only conventional devices were used.ResultsOverall, 80 patients (58 men, 65 ± 10 years) were enrolled. True bifurcations accounted for 64% of cases, with the left anterior descending artery/diagonal branch being the most frequent bifurcation site (n = 37, 46%) and left main coronary artery bifurcation being treated in 6 (8%) patients. Angiographic success was achieved in 78 (97.5%) patients through a 5 French guiding catheter whereas in two cases, a 5–6 French guiding catheter upgrade was required to optimize SB treatment after the main bifurcation vessel have been secured. Overall, procedural success was achieved in all but one patient who had periprocedural necrosis following multivessel PCI. Another patient underwent target bifurcation revascularization because of a critical restenosis in a significant SB yielding an acute coronary syndrome five months after the index procedure.ConclusionsThis study demonstrates the feasibility of transradial 5 French bifurcation intervention with nondedicated devices and preliminary supports its efficacy and safety over a wide range of bifurcation anatomy and complexity.
Synthesis and Evaluation of a 1,3a,6a‐Triazapentalene (TAP)‐Bonded System
Authors: Ito Masami , Mera Akane , Mashimo Takaki , Seki Tomohiro , Karanjit Sangita , Ohashi Eisaku , Nakayama Atsushi , Kitamura Kei , Hamura Toshiyuki , Ito Hajime , Namba Kosuke 
Published: October 2018

AbstractA method of synthesizing a directly connected 1,3a,6a‐triazapentalene (TAP) ring system as a linearly bonded aromatic system with a planar form was established. Various TAP‐dimers and a 2‐alkyl‐TAP‐trimer were synthesized and their fluorescence properties were evaluated. Although the direct connection of the TAP ring with other TAP rings did not affect the fluorescence properties in diluted solvent, TAP‐dimers showed unique fluorescence properties derived from the aggregation state under highly concentrated conditions. In particular, TAP‐dimer 5 f showed aggregation‐induced emission in highly concentrated solution, and 5 b showed typical mechanochromic fluorescence in the solid state despite their compact molecular size.
The prognostic value of 3 commonly measured blood parameters and geriatric assessment to predict overall survival in addition to clinical information in older patients with cancer
Authors: Baitar Abdelbari , Kenis Cindy , Decoster Lore , De Grève Jacques , Lobelle Jean‐Pierre , Flamaing Johan , Milisen Koen , Wildiers Hans 
Published: October 2018

BACKGROUNDThe current study was performed to evaluate the prognostic value of laboratory parameters and geriatric assessment (GA) in addition to a baseline model with clinical information regarding overall survival (OS) in patients with cancer.METHODSGA was systematically performed in patients aged ≥70 years. The baseline model consisted of age, tumor type, and stage of disease. The incremental prognostic values of the GA as a whole (10‐item GA) and laboratory parameters were assessed separately and combined. The parameters included hemoglobin (Hb), albumin, C‐reactive protein (CRP), and the Glasgow Prognostic Score (GPS). Analyses were conducted with continuous and dichotomized variables. Cox models were compared based on Akaike information criterion (ΔAIC) and their discriminatory ability was assessed using the concordance probability estimate (CPE).RESULTSA total of 328 patients were considered for this analysis. The baseline model had a CPE of 0.725. The addition of CRP, albumin, and Hb combined resulted in the best performing model (ΔAIC: 40.12 and CPE: 0.757) among the laboratory parameters. However, the 10‐item GA improved the baseline model even more (ΔAIC: 46.03 and CPE: 0.769). Similar results were observed in the analysis with dichotomous variables. The addition of the 3 laboratory parameters (CRP, albumin, and Hb) improved the CPE by 1.4% compared with the baseline model already extended with the 10‐item GA. The CPE increase (1.7%) was the highest with the GPS in the analysis with dichotomous variables.CONCLUSIONSGA appears to add slightly more prognostic information than laboratory parameters in addition to clinical information. The laboratory parameters have an additional prognostic value beyond clinical and geriatric information.
PPLTCAM: A parallel TCAM‐based IP address lookup structure with high incremental update performance
Authors: Wang Fei , Hong Yi , Xu Cong 
Published: October 2018

SummaryOn the analysis of DUOS, it is proposed a new pipeline TCAM‐Based structure for IP address lookup, PLTCAM. PLTCAM transforms the equal position of LTCAM and ITCAM into a pipeline structure, thus acquiring better search power consumption than DUOS and still maintaining the significant memory management performance on incremental updating of DUOS. In addition, a parallel processing structure, PPLTCAM, is presented to further improve the IP lookup performance of throughput. Simulation results show that PPLTCAM has the throughput performance of parallelism structures, maintaining the memory management performance on incremental updating and the low power consumption of PLTCAM. Therefore, PPLTCAM is an IP address lookup structure with good comprehensive performances.