bluuebunny/crossref_metadata_2025_split huggingface dataset:
A multi‐feature fusion graph attention network for decoding motor imagery intention in spinal cord injury patients
Authors: Leng Jiancai , Gao Licai , Jiang Xiuquan , Lou Yitai , Sun Yuan , Wang Chen , Li Jun , Zhao Heng , Feng Chao , Xu Fangzhou , Zhang Yang , Jung Tzyy-Ping 
Published: November 2024

Abstract

Objective. Electroencephalogram (EEG) signals exhibit temporal–frequency–spatial multi-domain feature, and due to the nonplanar nature of the brain surface, the electrode distributions follow non-Euclidean topology. To fully resolve the EEG signals, this study proposes a temporal–frequency–spatial multi-domain feature fusion graph attention network (GAT) for motor imagery (MI) intention recognition in spinal cord injury (SCI) patients. Approach. The proposed model uses phase-locked value (PLV) to extract spatial phase connectivity information between EEG channels and continuous wavelet transform to extract valid EEG information in the time–frequency domain. It then models as a graph data structure containing multi-domain information. The gated recurrent unit and GAT learn EEG’s dynamic temporal–spatial information. Finally, the fully connected layer outputs the MI intention recognition results. Main results. After 10 times 10-fold cross-validation, the proposed model can achieve an average accuracy of 95.82%. Furthermore, this study analyses the event-related desynchronization/event-related synchronization and PLV brain network to explore the brain activity of SCI patients during MI. Significance. This study confirms the potential of the proposed model in terms of EEG decoding performance and provides a reference for the mechanism of neural activity in SCI patients.
Narrative review of proximal tubular epithelial cell in-vitro co-culture models
Authors: Varda Luka , Petreski Tadej , Gradišnik Lidija , Maver Uroš , Bevc Sebastjan 
Published: November 2024

Abstract
Kidney diseases are among the leading causes of death globally. With the increasing rates of acute kidney injury (AKI) requiring hospitalisation, a better understanding of pathophysiological mechanisms is needed to treat the patients more efficiently. Nephrotoxicity is one of the most common causes of AKI, mainly due to the high availability of over-the-counter drugs and natural supplements, which may interact with prescribed drugs at the level of pharmacokinetics, among other factors. The latter can lead to clinically relevant complications (including AKI), which is even more pronounced given the increasingly ageing population in the Western world and the associated increase in polypharmacy. Drug testing starts at the preclinical level, where a reliable model is needed to predict human response to a tested drug with sufficient accuracy. Recently, in-vitro kidney models of different complexities have been created to study various aspects of kidney diseases. Because the proximal tubule plays a vital role in several mechanisms, many models include proximal tubular epithelial cells (PTECs). Monocultures of PTECs do not represent in-vivo tissue accurately enough. Therefore, more complex models with more cell types are being built. To our knowledge, this is the first review focusing on co-culture models and cell types used alongside PTECs for studying the nephrotoxicity of drugs and other mechanisms of AKI and chronic kidney disease.
Novel in situ and rapid self-gelation recombinant collagen-like protein hydrogel for wound regeneration: mediated by metal coordination crosslinking and reinforced by electro-oxidized tea polyphenols
Authors: Sun Yue , Gao Cungang , Jia Pengxin , Song Liang , Kang Jia , Han Min , Yu Wenfa , Nian Rui 
Published: November 2024

Abstract
Recombinant collagen holds immense potential in the development of medical functional materials, yet its widespread application remains hindered by the absence of a suitable self-assembly strategy. In this article, we report the discovery that the bacterial-derived collagen-like (CL) protein Scl2 can rapidly self-gelation (∼1 min at pH ∼7) due to properties enabled by metal coordination crosslinking. This was achieved by fusing metal ion chelating peptides to both termini of the protein. Our research further reveals the critical role of electrostatic interaction between globular domains (V domains) of recombinant collagen in the self-assembly process. We show that modifying the negative charge load of the N-terminal α-helix of the V domain enables control over the self-assembly time (from 1 min to 30 min) and strength (from 8 kPa to 26 kPa) of the Scl2 hydrogel. By adjusting the molecular weight of the core CL domain, we have remarkably further enhanced the strength of the Scl2 hydrogel to 78 kPa. Moreover, we innovatively employed electro-oxidized tea polyphenols to enhance the stability of the Scl2 hydrogel, resulting in the formation of a reliable self-assembled metal coordination hydrogel at physiological temperature. This approach not only eliminates the need for toxic chemical crosslinking agents but also confers the material with multiple functionalities, such as adhesion, antibacterial, and antioxidant properties. The novel recombinant Scl2 hydrogel exhibited exceptional in situ self-gelation and injectable properties. This innovative hydrogel not only demonstrates remarkable biological activity but also exhibits remarkable tissue repair-promoting capabilities in full-thickness skin injury models (shorten healing cycle by more than 30%). The convenient and versatile nature of this recombinant collagen hydrogel makes it promising for clinical applications in injury treatment, demonstrating broad applications in the future.
Bioprinting a resilient and transparent cornea stroma equivalent: harnessing dual crosslinking strategy with decellularized cornea matrix and silk fibroin hybrid
Authors: Ghosh Anwesha , Bera Ashis Kumar , Ghosh Soham , Singh Vivek , Basu Sayan , Pati Falguni 
Published: November 2024

Abstract
Bioprinting a resilient yet optically transparent corneal tissue substitute remains a challenge. In this study we introduce an innovative methodology aimed at bolstering the mechanical and optical attributes of silk fibroin (SF) hydrogels, pivotal for the progression of cornea tissue engineering. We devised a unique eosin Y-based photoinitiator system to instigate di-tyrosine linkages within highly concentrated pristine SF solutions under green light exposure. This pioneering technique resulted in SF hydrogels fortified by dityrosine covalent bonds, preserving exceptional transparency and soft elastomeric qualities devoid of spontaneous transitions to stiff, opaque beta-sheet conformations. Furthermore, we synergistically combined SF with decellularized cornea matrix (DCM) hydrogel, leveraging photo-polymerization under green light followed by thermal gelation to establish resilient and stable gel formation. The ensuing dual crosslinked hybrid hydrogels exhibited superior mechanical and thermal resilience in comparison to dual crosslinked DCM hydrogels. The inclusion of SF in DCM further augmented the hydrogel’s elasticity and shear recovery, positioning it as an optimal bioink for cornea bioprinting endeavors. During the extrusion printing process, photocrosslinking of the bioink superficially fortified SF and DCM polymer chains via di-tyrosine linkages, furnishing initial stability and mechanical fortitude. Subsequent post-printing thermal gelation further reinforced collagen chains through self-assembly. Notably, the bioprinted cornea constructs, housing human limbal mesenchymal stem cells, manifested transparency, structural integrity, and optimal functionality, underscored by the expression of keratocyte proteoglycans. In summation, our engineered 3D constructs exhibit promising potential for in vivo applications in cornea tissue engineering, marking a significant stride forward in the field’s advancement.
Climate change perceptions, expectations, observations, and projections at Lake Victoria
Authors: Liersch Stefan , Broek Karlijn van den , Pilz Tobias , Isyaku Usman , Chappin Maryse , Böhm Gisela , Mbilingi Bwambale , Luomba Joseph , Awuor Fonda Jane , Kayanda Robert , Mahongo Shigalla , Ogunbode Charles , Nyamweya Chrispine , Kubiriza Godfrey K. , Wanguche Patrick Otuo , Aura Christopher Mulanda , Kishe Mary A. , Okello William , Kariuki Paul Njoroge , Adam Emelda Teikwa , Koch Hagen 
Published: November 2024

Abstract
Understanding people's perceptions of climate change and associated environmental risks is paramount in assessing how individuals respond to climate change. Awareness of the consequences of climate change determines the present and future behaviours and expectations, as well as the actions taken to mitigate the likely impacts. We surveyed the perceived and expected climate change consequences of experts and community members in the Lake Victoria basin in East Africa, compared them with hydro-meteorological observations and projections, and established that some perceived trends, such as increasing temperature or rainfall intensity, correspond with meteorological observations. However, the perceived increase in drought occurrence (believed to be a recent consequence), was not substantiated by the meteorological data. It was only in the northwestern region that drought frequency increased since the year 2000, while the rest of the basin did not experience such a trend. Community members were concerned about the already noticeable consequences of climate change on their livelihoods through agriculture or fishing, while experts were mainly focused on the amplification of hazards such as floods and droughts. This divergence may imply that experts underestimate the consequences that society is already facing. Nevertheless, both groups expect that climate change will undoubtedly lead to the deterioration of human well-being by affecting food security, increasing poverty, and increasing the incidence of disease. This is a serious concern that requires immediate attention. Such insights into people's climate change perceptions can help policy-makers, researchers, and community members to better tailor adaptation solutions acceptable to the local context. Effective governance is essential to enable people to adapt to climate change and other challenges, including those resulting from the impacts of globalisation, demographic trends, and the degradation and scarcity of resources.
Urban building energy models: how can we improve the treatment of uncertainty for energy policy decision-making?
Authors: Fennell Pamela J , Ebrahimigharehbaghi Shima , Mata Érika , Kokogiannakis Georgios , Amrith Shyam , Ignatiadou Sotiria , Piamo Samuele Lo 
Published: November 2024

Abstract
Urban Building Energy Models (UBEMs) are emerging as a powerful tool for cities and regions seeking to make decisions on the best pathways for increasing the energy efficiency of their buildings. As model results are used to inform critical policy decisions, it is essential to understand and communicate the limits of inference of model results and how sensitive they are to changes in inputs. In the absence of standard datasets and protocols for model validation, Uncertainty Analysis and Sensitivity Analysis (UASA) procedures offer vital insights. However, there is no consensus on how UASA should be applied to bottom-up building physics-based UBEMs, nor on how different use cases might influence the choice of UASA approach. This study uses a systematic review of the literature (2009–2023) to explore the procedures which are applied and assess their appropriateness. We find a need for a more holistic view of uncertainty to be taken, and present a decision framework for selecting the most appropriate form of quantitative sensitivity analysis, based on model form, data provenance and use case. We also propose a number of approaches to improve the application of sensitivity analysis in UBEM studies, including the importance of undertaking a complementary assessment of information quality.
Femtosecond laser micro/nano processing: from fundamental to applications
Authors: Gao Le , Zhang Qiming , Gu Min 
Published: November 2024

Abstract
Able to precisely control and manipulate materials’ states at micro/nano-scale level, femtosecond (fs) laser micro/nano processing technology has undergone tremendous development over the past three decades. Free-forming three-dimensional (3D) microscale functional devices and inducing fascinating and unique physical or chemical phenomena have granted this technology powerful versatility that no other technology can match. As this technology advances rapidly in various fields of application, some key challenges have emerged and remain to be urgently addressed. This review firstly introduces the fundamental principles for understanding how fs laser pulses interact with materials and the associated unique phenomena in section 2. Then micro/nano-fabrication in transparent materials by fs laser processing is presented in section 3. Thereafter, several high efficiency/throughput fabrication methods as well as pulse-shaping techniques are listed in sections 4 and 5 reviews four-dimensional (4D) and nanoscale printing realized by fs laser processing technology. Special attention is paid to the heterogeneous integration (HI) of functional materials enabled by fs laser processing in section 6. Several intriguing examples of 3D functional micro-devices created by fs laser-based manufacturing methods such as microfluidics, lab-on-chip, micro-optics, micro-mechanics, micro-electronics, micro-bots and micro-biodevices are reviewed in section 7. Finally, a summary of the review and a perspective are proposed to explore the challenges and future opportunities for further betterment of fs laser micro/nano processing technology.
Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair
Authors: Shao Huifeng , Xia Pengcheng , Zhang Tao , Shi Jinyuan , Huang Zhiqiang , Yuan Xianqi , Nian Zhiheng , Zhao Xiao , Zhou Rougang , Gong Youping , He Yong 
Published: November 2024

Abstract
In clinical practice, the irregular shapes of traumas pose a significant challenge in rapidly manufacturing personalized scaffolds. To address these challenges, inspired by LEGO® bricks, this study proposed a novel concept of modular scaffolds and developed an innovative system based on machine vision for their rapid and intelligent assembly tailored to defect shapes. Trapezoidal interfaces effectively connect standardized bone units based on magnesium-doped silicate calcium, ensuring high stability of the modular scaffolds, with compressive strength up to 135 MPa and bending strength up to 17 MPa. Through self-developed defect recognition and reconstruction algorithms, defect recognition and personalized assembly schemes for bone scaffolds can be achieved autonomously. Modular scaffolds seamlessly integrate with surrounding bone tissue, promoting new bone growth, with no apparent differences compared to fully 3D printed integral scaffolds in the skull and femur repair experiments. In summary, the adoption of modular scaffolds not only integrates personalization and standardization but also satisfies the optimal treatment window.
The resilience value of residential solar + storage systems in the continental U.S.
Authors: Baik Sunhee , Miller Cesca , Carvallo Juan Pablo 
Published: November 2024

Abstract
Behind the meter rooftop solar plus storage (PVESS) has the potential to benefit the hosting customers by providing affordability, environmental, and reliability and resilience value. Whereas the bill reduction and environmental benefits of PVESS are well studied, its monetary resilience benefits are less understood. The increasing trend of power interruptions driven by extreme weather events heightens the need to understand these benefits. This study leverages various publicly available datasets to perform a cost benefit analysis of adding to determine the resilience value of PVESS for a typical single family home in each county in the continental U.S. We find that PVESS is very effective to technically mitigate interruptions across the country. However, the monetary benefits in the base case only cover about 14% of battery costs, with no county exceeding 60%. This is somewhat expected, given that PVESS provide other monetary benefits that are not part of this analysis. Through sensitivities, we find that higher frequency of extreme weather events roughly triples the resilience value of PVESS and that higher values of lost load double the same metric. Our sensitivity analysis shows that the benefit cost ratio of PVESS for customers living in areas with higher-than-average frequency of long duration interruptions and value of lost load is already above one even without considering other value streams. We conclude with recommendations that regulators and utilities could implement to enable customers to calculate and capture the resilience value of PVESS more efficiently.
Scaling rainwater harvesting for irrigation in Kenya: potential sustainability risks and the need for adaptive governance
Authors: Singh Radhika , Oguge Nicholas , Odote Collins 
Published: November 2024

Abstract
Rainwater harvesting for irrigation (RWHI) systems offer many benefits to smallholder farmers in Kenya, including the possibility of agricultural intensification and improved resilience to climate change in more arid areas. However, the scaling of RWHI systems could inadvertently pose risks to environmental, social, and economic sustainability. Governance institutions in Kenya tasked with managing RWHI adoption processes are often unaware of such risks and ill-equipped to manage them when they emerge. To address this gap, this article first presents key insights from the literature on innovation scaling and adaptive governance on how undesirable effects of scaling can be mitigated. Then, based on the results of a global literature review and a case study in Kenya, it outlines potential environmental, social, and economic risks of scaling RWHI that may manifest in the Kenyan context. Environmentally, the biggest risk is that widespread adoption of RWHI, while increasing water availability at the household level, will alter hydrological flows and impact ecosystem functioning. Socially, major risks of scaling RWHI include increased inequities in water access and rights, as those with the resources to adopt RWHI are able to store and use more water than others. Finally, economic risks may emerge when farmers who have adopted RWHI to grow cash crops experience heightened vulnerability to market fluctuations. The article ends with a discussion on governance approaches that could be applied to ensure responsible RWHI scaling in Kenya. Key recommendations include creating institutions that embed adaptive governance mechanisms, democratizing the development of scaling strategies to ensure their collective ownership, and enhancing monitoring and data collection capacities for effective response. These measures aim to balance short-, medium-, and long-term objectives across various scales and user groups to maximize sustainability outcomes during RWHI scaling processes.
A systematic review of progress in food security research and implications for achievement of the UN’s zero-hunger goal in Bangladesh
Authors: Hossain Abdul Mohammed Mokter , Hossain Md Sarwar , Tortajada Cecilia 
Published: November 2024

Abstract
Despite numerous policy initiatives to achieve food security, more than 2 billion people are food insecure across the world. Food security research can help addressing food insecurity effectively by summarizing the state of knowledge and providing future research direction to make sure no one is left behind. Yet, there are no comprehensive studies of food security research in Global South countries such as in Bangladesh, where nearly one-third of the population is food insecure. Here, this systematic review aims to identify the progress, gaps, and future research directions for food security in Bangladesh by investigating current research trends and the influence of socioeconomic and environmental drivers on food security and recommend policy interventions for achieving the zero-hunger goal of the Sustainable Development Goals (SDGs). We systematically reviewed articles both quantitatively and qualitatively and summarized the trends, methods, challenges, and opportunities of food security research in Bangladesh. Our findings reveal that longitudinal trends and inequality in food security across administrative and agroecological zones are underexplored. Moreover, most studies focused on the influence of socioeconomic drivers, with insufficient attention to environmental drivers, and none examined the causal relationships among them. The access and availability dimensions of food security are the most studied, while stability and utilization are the least addressed in food security research. Addressing these gaps is essential for establishing a sustainable food system that may help Bangladesh achieving the SDG target of ending hunger (SDG 2) and ensuring no one is left behind.
Introduction: Victimhood in Transition
Authors: Lawther Cheryl 
Published: November 2024

AbstractChapter 1 sets the book in its scholarly and empirical context. The chapter begins by setting out the two key pillars of scholarly work on which this book rests. The first part of the chapter, ‘The Rise of the Victim’, contextualises the growing centrality of victims in transitional justice and elaborates on claims of a mismatch between the rhetoric and reality of victim centrism. The second part of the chapter, ‘Defining Victimhood: Innocence, Guilt, and Beyond’, traces the conceptualisation and construction of victimhood in criminology and transitional justice. The chapter then establishes the empirical foundations of the book, providing a brief overview of the Northern Ireland conflict, the nature of victimhood, and the politicisation of pain. A discussion on the research design and methodological considerations which informed the fieldwork on which the book is based follows. The chapter concludes by offering a brief overview of the chapters to come.
Victimhood and Voice
Authors: Lawther Cheryl 
Published: November 2024

AbstractThe objective of Chapter 4 is to go beyond the existing theory and practice on ‘victim-centred’ transitional justice to examine the challenges, dangers, and contradictions that are inherent to the exercise of victims’ voices. The chapter argues that what we come to hear and know as ‘victims’ voices’ shapes the construction and reproduction of victimhood and often does so in profoundly discomforting ways. The chapter addresses three overlapping areas. First, the chapter examines the intersection between the use of victims’ voices and political claims-making. Second, the chapter addresses the ossification of victims’ voices around their experience of death and injury, with the risk that victims become defined ‘by’ their voice and their identity is reduced to the point of trauma. Third, the chapter turns to a critical examination of the argument that victimhood confers epistemic privilege and how this assumed privilege translates regarding hearing and receiving voice.
Victimhood and the Haunting of Lives, Landscapes, and Unresolved Pasts
Authors: Lawther Cheryl 
Published: November 2024

AbstractBuilding on approaches to ghosts and haunting by Gordon (1997), Chapter 7 focuses on the haunting presence of the unresolved past and its impact on the construction, reproduction, and politicisation of victimhood. This chapter argues for three conceptualisations of haunting when past traumas remain unaddressed. The first of these—‘Haunting and Lost Lives’—examines the haunting impact of the failure to deal with the legacy of conflict by way of truth, justice, or reparations for example. Under the heading of ‘The Haunting of Landscape’, the second part of the chapter examines how landscape and physical structures are also capable of ‘holding’ memories, conjuring up and housing spectres of the past. The final conceptual theme—‘Victimhood, Haunting, and Trauma’—critically explores how the failure to comprehensively deal with the legacy of conflict and human rights abuses can contribute to high levels of conflict-related mental health problems and transgenerational trauma.