bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental advanced RNP to xLS approaches with vertical path coding and automatic landings
Authors: Dautermann T. , Ludwig T. , Geister R. , Blase T. 
Published: September 2018

ABSTRACTWe report on the flight test results of an Airbus 320 during novel advanced required navigation performance (RNP) procedures which contain a fixed radius turn that delivers the aircraft onto a short instrument landing system (ILS) precision final. Moreover, the advanced RNP part contains altitude constraints and/or a coded vertical path angle. The approaches were flown automatically with guidance and autothrust as computed by the flight management system. We investigated the use of the fixed radius in conjunction with vertical path options onto (a) the performance of the speed profile for arrival time optimisation, (b) the vertical path during the RNP part of the procedure and (c) the performance of the autoland capability after a curved transition onto an ILS.For the trials, we designed five instrument approaches to a runway equipped with ILS. A RF curve terminates at the ILS intercept point at heights of 550, 750, 1000, 1500 and 2000 ft above aerodrome level and each approach had four different initial approach fixes which corresponded to a track angle change of 30°, 60°, 90° and 180° during the constant radius turn-to-final. We constructed the procedure such that the altitude constraints at initial, intermediate and final approach fix describe a continuous vertical path with minus 2° inclination, transitioning to the –3° glide path of the ILS and intercepting the glide path from below. In all cases, the land mode of the flight guidance computer became active between 316 and 381ft radar altitude. The vertical path following error depended on the coding of the procedure in the database. With coded vertical path angle and altitude constraints, the vertical path following error was never greater than +57 m (above desired flight path) during the RNP part when flown by the automatic flight guidance system without any pilot intervention.
Clostridium difficile colonization among patients with clinically significant diarrhea and no identifiable cause of diarrhea
Authors: Dubberke Erik R. , Reske Kimberly A. , Hink Tiffany , Kwon Jennie H. , Cass Candice , Bongu Jahnavi , Burnham Carey-Ann D. , Henderson Jeffrey P. 
Published: September 2018

AbstractObjectiveTo determine the prevalence of Clostridium difficile colonization among patients who meet the 2017 IDSA/SHEA C. difficile infection (CDI) Clinical Guideline Update criteria for the preferred patient population for C. difficile testing.DesignRetrospective cohort.SettingTertiary-care hospital in St. Louis, Missouri.PatientsPatients whose diarrheal stool samples were submitted to the hospital’s clinical microbiology laboratory for C. difficile testing (toxin EIA) from August 2014 to September 2016.InterventionsElectronic and manual chart review were used to determine whether patients tested for C. difficile toxin had clinically significant diarrhea and/or any alternate cause for diarrhea. Toxigenic C. difficile culture was performed on all stool specimens from patients with clinically significant diarrhea and no known alternate cause for their diarrhea.ResultsA total of 8,931 patients with stool specimens submitted were evaluated: 570 stool specimens were EIA positive (+) and 8,361 stool specimens were EIA negative (−). Among the EIA+stool specimens, 107 (19% of total) were deemed eligible for culture. Among the EIA− stool specimens, 515 (6%) were eligible for culture. One EIA+stool specimen (1%) was toxigenic culture negative. Among the EIA− stool specimens that underwent culture, toxigenic C. difficile was isolated from 63 (12%).ConclusionsMost patients tested for C. difficile do not have clinically significant diarrhea and/or potential alternate causes for diarrhea. The prevalence of toxigenic C. difficile colonization among EIA− patients who met the IDSA/SHEA CDI guideline criteria for preferred patient population for C. difficile testing was 12%.
Gender similarity, coworker support, and job attitudes: An occupation’s creative requirement can make a difference
Authors: Koseoglu Gamze , Blum Terry C , Shalley Christina E 
Published: September 2018

AbstractBy introducing gender similarity as a contextual antecedent of coworker support, we examined the mediating role of coworker support for the relationship between workgroup gender similarity and job attitudes. In addition, we explored how a creative requirement, which is an occupational characteristic, can influence the relationship between coworker support and job attitudes above and beyond the role of supervisor support and organizational support. Results based on 975 full-time employees across a wide variety of occupations and industries indicated that as expected coworker support can serve as an underlying mechanism in the relationship between the relational demography of a workplace and employees’ job satisfaction and intention to quit. Furthermore, coworker support was significantly related to job satisfaction only for those occupations that required high levels of creativity. Finally, the creative requirement of an occupation moderated the indirect effect of gender similarity on job satisfaction through coworker support.
Oscillation and variation for the Riesz transform associated with Bessel operators
Authors: Wu Huoxiong , Yang Dongyong , Zhang Jing 
Published: September 2018

Let λ > 0 and letbe the Bessel operator on ℝ+ := (0,∞). We show that the oscillation operator 𝒪(RΔλ,∗) and variation operator 𝒱ρ(RΔλ,∗) of the Riesz transform RΔλ associated with Δλ are both bounded on Lp(ℝ+, dmλ) for p ∈ (1,∞), from L1(ℝ+, dmλ) to L1,∞(ℝ+, dmλ), and from L∞(ℝ+, dmλ) to BMO(ℝ+, dmλ), where ρ ∈ (2,∞) and dmλ(x) := x2λ dx. As an application, we give the corresponding Lp-estimates for β-jump operators and the number of up-crossings.
Migration and a New Landscape of Forest Use and Conservation
Authors: Robson James P. , Klooster Daniel J. 
Published: September 2018

SummaryThe nature of migration–forest linkages in migrant-sending regions is underreported and poorly understood. In rural Latin America and elsewhere, out-migration, together with agricultural crises and the deterritorialization of rural livelihood, are transforming forests and the communities that manage them. Drawing on research in indigenous communities of Oaxaca (Mexico), we identify the parameters of a new landscape of forest use and conservation, finding that: migration challenges community practices for self-governance of forest resources; declines in agriculture create new spaces for forest recovery and use; and forest conservation policies create economic opportunities around both extractive and non-extractive forest use.
The Perceived Benefits of Protected Areas in the Virunga-bwindi Massif
Authors: Tolbert Sarah , Makambo Wellard , Asuma Stephen , Musema Altor , Mugabukomeye Benjamin 
Published: September 2018

SummaryDespite decades of continuous research highlighting the biological success of mountain gorilla conservation in the Virunga-Bwindi Massif, there is little knowledge of whether people living near the mountain gorilla parks perceive benefits from protected areas (PAs). This paper is the first study in the region to use the sustainable livelihoods framework to understand drivers of local perceptions of PA benefits. We used a logit regression to examine the relationship between household socioeconomic characteristics and the costs and benefits that 752 men and women living near mountain gorilla PAs reported. Integrated conservation and development projects (ICDPs) in the Virunga-Bwindi Massif have improved perceptions of mountain gorilla PAs, but they need to prioritize projects that improve human and social capital. The frustration voiced about inequitable benefit distribution highlights the need for further social equity research to ensure ICDPs, including revenue-sharing schemes, are managed transparently and equitably.
Pericarp thickness of Korean maize landraces
Authors: So Yoon-Sup 
Published: September 2018

AbstractThin pericarp is one of crucial selection criteria for high-tender waxy corn hybrid development. A pericarp thickness of 2414 maize landrace accessions including 87 public waxy inbred lines was investigated to select accessions with thin pericarp and to broaden genetic diversity among waxy corn cultivars. Observed pericarp thickness of the 2414 accessions ranged from 16.0 ± 1.56 to 139.2 ± 39.55 µm with the average of 47.7 ± 13.15 µm. More than half of the accessions were below the suggested thickness of <50 µm for high-tender waxy corn hybrid development. Large sample size resulted in significant differences among endosperm types and among collection provinces. This, however, may not translate into considerable difference in tenderness since most averages of different types and collection provinces were <50 µm. Positive correlation (r= 0.55) between the average and standard deviation of pericarp thickness implied that more samples are needed to achieve same level of precision when it comes to selection for thick pericarp than that for thin pericarp. Top 10% thin-pericarped waxy landrace accessions were intercrossed to form a new waxy corn population from this result.
Cassini/MIMI Observations on the Dungey Cycle Reconnection and Kelvin‐Helmholtz Instability in Saturn's Magnetosphere
Authors: Dialynas Konstantinos 
Published: September 2018

AbstractA new composite analysis of ∼13 years of Cassini's Charge Energy Mass Spectrometer measurements, presented by Allen et al. (2018, https://doi.org/10.1029/2018JA025262), suggests that the asymmetrically distributed suprathermal He++ in Saturn's magnetosphere is due to Dungey cycle related reconnection and Kelvin‐Helmholtz instabilities that provide paths to the solar wind plasma to reach distances even deep in the inner magnetosphere and accumulate in the ring current region, together with the internally sourced plasma. The results provide a significant addition to the ongoing discussions concerning the contribution of the solar wind input to the dynamics of an otherwise rotationally driven system, such as Saturn's magnetosphere.
Satellite Detection of Water Stress Effects on Terrestrial Latent Heat Flux With MODIS Shortwave Infrared Reflectance Data
Authors: Yao Yunjun , Liang Shunlin , Cao Bao , Liu Shaomin , Yu Guirui , Jia Kun , Zhang Xiaotong , Zhang Yuhu , Chen Jiquan , Fisher Joshua B. 
Published: September 2018

AbstractThe MODerate‐resolution Imaging Spectroradiometer (MODIS) provides spatially contiguous measurements of terrestrial biophysical variables, which can be used to estimate the terrestrial latent heat flux (LE). MODIS‐derived shortwave infrared reflectance (SWIR) metrics (SWIRs) are sensitive to the soil moisture and vegetation water stress. In this study, we used the MODIS‐derived SWIRs with eddy covariance flux measurements obtained from 25 flux tower sites representing 10 different land cover types within China to evaluate the sensitivity of SWIRs to ground‐measured evaporation fraction and LE. The water constraint metrics determined using the MODIS‐derived SWIR generally corresponded better with the ground‐measured evaporation fraction values than those obtained without using SWIR. The MODIS‐derived SWIRs were used as proxies for the soil and vegetation water supply constraints in a revised Priestley‐Taylor algorithm to estimate the terrestrial LE. The estimated LE using the MODIS‐derived SWIRs generally corresponded well with the ground‐measured LE (0.56 ≤ R2 ≤ 0.97) for most of the flux tower sites. Regional algorithm sensitivity analysis using the MODIS‐derived SWIRs as water supply proxies demonstrated that water limitations reduce LE by more than 53% over China, and the atmospheric vapor pressure deficit and relative humidity are not sufficient to characterize both the atmosphere demand and water supply for LE estimation. Our results demonstrate the potential of using MODIS‐derived SWIRs to characterize soil and vegetation water supply factors for determining LE, where the relatively high spatial and temporal resolutions (500 m and daily) are closer to the scale of the eddy covariance ground measurements.
Methyl, Ethyl, and Propyl Nitrates: Global Distribution and Impacts on Reactive Nitrogen in Remote Marine Environments
Authors: Fisher Jenny A. , Atlas Elliot L. , Barletta Barbara , Meinardi Simone , Blake Donald R. , Thompson Chelsea R. , Ryerson Thomas B. , Peischl Jeff , Tzompa‐Sosa Zitely A. , Murray Lee T. 
Published: September 2018

AbstractAlkyl nitrates (RONO2) are important components of tropospheric reactive nitrogen that serve as reservoirs for nitrogen oxides (NOx≡ NO + NO2). Here we implement a new simulation of atmospheric methyl, ethyl, and propyl nitrate chemistry in a global chemical transport model (GEOS‐Chem). We show that the model can reproduce the spatial and seasonal variability seen in a 20‐year ensemble of airborne observations. Methyl nitrate accounts for 17 Gg N globally, with maxima over the tropical Pacific and Southern Ocean. Propyl nitrate is enhanced in continental boundary layers, but its global impact (6 Gg N) is limited by a short lifetime (8 days vs. 26 days for methyl nitrate and 14 days for ethyl nitrate) that inhibits long‐range transport. Ethyl nitrate has the smallest impact of the three species (4 Gg N). We find that methyl nitrate is the dominant form of reactive nitrogen (NOy) in the Southern Ocean marine boundary layer, where its addition to the model corrects a large NOy underestimate in austral winter relative to recent aircraft data. RONO2 serve as a small net NOx source to the marine troposphere, except in the northern midlatitudes where the continental outflow is enriched in precursors that promote NOx loss via RONO2 formation. Recent growth in NOx emissions from East Asia has enhanced the role of RONO2 as a source of NOx to the remote free troposphere. This relationship implies projected future NOx emissions growth across the southern hemisphere may further enhance the importance of RONO2 as a NOx reservoir.
Sheet Flow Effects on Sediment Transport in a Degraded Ridge‐and‐Slough Wetland: Insights Using Molecular Markers
Authors: Regier Peter , He Ding , Saunders Colin J. , Jara Blanca , Hansen Chris , Newman Sue , Tate‐Boldt Erik , Coronado‐Molina Carlos , Jaffé Rudolf 
Published: September 2018

AbstractWetland ecosystems are often characterized by self‐organized landscape patterning, driven by abiotic and biotic factors. In the Florida Everglades, natural sheet flow is hypothesized to have distributed sediments to form the pattern of linear emergent ridges and submerged sloughs. Drainage and barriers to flow have degraded these microtopographic features. As part of the Comprehensive Everglades Restoration Plan, the Decompartmentalization Physical Model is a landscape‐scale experiment to evaluate ecosystem responses to restored sheet flow by increasing freshwater inputs and removing barriers to flow. To test the proposed mechanism that flow rebuilds ridge‐slough microtopography by remobilizing slough sediments into ridges, four molecular markers capable of distinguishing ridge, slough, and microbial sources were evaluated in flocculent benthic sediments (floc) and advected sediments (collected in traps) during preflow, high‐flow, and postflow conditions over 4 years. The combined use of the four biomarkers, namely, the aquatic proxy (Paq), C20 highly branched isoprenoids, kaurenes, and botryococcenes, showed compositional patterns that clearly distinguished ridge and slough organic matter. Of these molecular parameters, the Paq was the most reliable in distinguishing among organic matter sources. Long‐term patterns in floc Paq at ridge and slough sites indicate a general increase, indicative of preferential mobilization of slough material. The Paq values for advected sediments are also strongly associated with slough environments, supporting temporal trends in floc samples. Our results tentatively confirm the hypothesis that increased flow in degraded ridge‐and‐slough wetlands, and associated sediment transport, is a potentially viable mechanism to restore historic patterns of microtopography.
Cross-exchange of B-vitamins underpins a mutualistic interaction between Ostreococcus tauri and Dinoroseobacter shibae
Authors: Cooper Matthew B , Kazamia Elena , Helliwell Katherine E , Kudahl Ulrich Johan , Sayer Andrew , Wheeler Glen L , Smith Alison G 
Published: September 2018

Abstract
Ostreococcus tauri, a picoeukaryotic alga that contributes significantly to primary production in oligotrophic waters, has a highly streamlined genome, lacking the genetic capacity to grow without the vitamins thiamine (B1) and cobalamin (B12). Here we demonstrate that the B12 and B1 auxotrophy of O. tauri can be alleviated by co-culturing with a heterotrophic bacterial partner Dinoroseobacter shibae, a member of the Rhodobacteraceae family of alpha-proteobacteria, genera of which are frequently found associated with marine algae. D. shibae lacks the complete pathway to synthesise three other B-vitamins: niacin (B3), biotin (B7), and p-aminobenzoic acid (a precursor for folate, B9), and the alga is in turn able to satisfy the reciprocal vitamin requirements of its bacterial partner in a stable long-term co-culture. Bioinformatics searches of 197 representative marine bacteria with sequenced genomes identified just nine species that had a similar combination of traits (ability to make vitamin B12, but missing one or more genes for niacin and biotin biosynthesis enzymes), all of which were from the Rhodobacteraceae. Further analysis of 70 species from this family revealed the majority encoded the B12 pathway, but only half were able to make niacin, and fewer than 13% biotin. These characteristics may have either contributed to or resulted from the tendency of members of this lineage to adopt lifestyles in close association with algae. This study provides a nuanced view of bacterial–phytoplankton interactions, emphasising the complexity of the sources, sinks and dynamic cycling between marine microbes of these important organic micronutrients.
Mapping of histone-binding sites in histone replacement-completed spermatozoa
Authors: Yoshida Keisuke , Muratani Masafumi , Araki Hiromitsu , Miura Fumihito , Suzuki Takehiro , Dohmae Naoshi , Katou Yuki , Shirahige Katsuhiko , Ito Takashi , Ishii Shunsuke 
Published: September 2018

AbstractThe majority of histones are replaced by protamines during spermatogenesis, but small amounts are retained in mammalian spermatozoa. Since nucleosomes in spermatozoa influence epigenetic inheritance, it is important to know how histones are distributed in the sperm genome. Conflicting data, which may result from different conditions used for micrococcal nuclease (MNase) digestion, have been reported: retention of nucleosomes at either gene promoter regions or within distal gene-poor regions. Here, we find that the swim-up sperm used in many studies contain about 10% population of sperm which have not yet completed the histone-to-protamine replacement. We develop a method to purify histone replacement-completed sperm (HRCS) and to completely solubilize histones from cross-linked HRCS without MNase digestion. Our results indicate that histones are retained at specific promoter regions in HRCS. This method allows the study of epigenetic status in mature sperm.
Locally-curved geometry generates bending cracks in the African elephant skin
Authors: Martins António F. , Bennett Nigel C. , Clavel Sylvie , Groenewald Herman , Hensman Sean , Hoby Stefan , Joris Antoine , Manger Paul R. , Milinkovitch Michel C. 
Published: September 2018

AbstractAn intricate network of crevices adorns the skin surface of the African bush elephant, Loxodonta africana. These micrometre-wide channels enhance the effectiveness of thermal regulation (by water retention) as well as protection against parasites and intense solar radiation (by mud adherence). While the adaptive value of these structures is well established, their morphological characterisation and generative mechanism are unknown. Using microscopy, computed tomography and a custom physics-based lattice model, we show that African elephant skin channels are fractures of the animal brittle and desquamation-deficient skin outermost layer. We suggest that the progressive thickening of the hyperkeratinised stratum corneum causes its fracture due to local bending mechanical stress in the troughs of a lattice of skin millimetric elevations. The African elephant skin channels are therefore generated by thickening of a brittle material on a locally-curved substrate rather than by a canonical tensile cracking process caused by frustrated shrinkage.
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination
Authors: Gustafsson Nina M. S. , Färnegårdh Katarina , Bonagas Nadilly , Ninou Anna Huguet , Groth Petra , Wiita Elisee , Jönsson Mattias , Hallberg Kenth , Lehto Jemina , Pennisi Rosa , Martinsson Jessica , Norström Carina , Hollers Jessica , Schultz Johan , Andersson Martin , Markova Natalia , Marttila Petra , Kim Baek , Norin Martin , Olin Thomas , Helleday Thomas 
Published: September 2018

AbstractThe glycolytic PFKFB3 enzyme is widely overexpressed in cancer cells and an emerging anti-cancer target. Here, we identify PFKFB3 as a critical factor in homologous recombination (HR) repair of DNA double-strand breaks. PFKFB3 rapidly relocates into ionizing radiation (IR)-induced nuclear foci in an MRN-ATM-γH2AX-MDC1-dependent manner and co-localizes with DNA damage and HR repair proteins. PFKFB3 relocalization is critical for recruitment of HR proteins, HR activity, and cell survival upon IR. We develop KAN0438757, a small molecule inhibitor that potently targets PFKFB3. Pharmacological PFKFB3 inhibition impairs recruitment of ribonucleotide reductase M2 and deoxynucleotide incorporation upon DNA repair, and reduces dNTP levels. Importantly, KAN0438757 induces radiosensitization in transformed cells while leaving non-transformed cells unaffected. In summary, we identify a key role for PFKFB3 enzymatic activity in HR repair and present KAN0438757, a selective PFKFB3 inhibitor that could potentially be used as a strategy for the treatment of cancer.
Circuit quantum electrodynamics of granular aluminum resonators
Authors: Maleeva N. , Grünhaupt L. , Klein T. , Levy-Bertrand F. , Dupre O. , Calvo M. , Valenti F. , Winkel P. , Friedrich F. , Wernsdorfer W. , Ustinov A. V. , Rotzinger H. , Monfardini A. , Fistul M. V. , Pop I. M. 
Published: September 2018

AbstractGranular aluminum (grAl) is a promising high kinetic inductance material for detectors, amplifiers, and qubits. Here we model the grAl structure, consisting of pure aluminum grains separated by thin aluminum oxide barriers, as a network of Josephson junctions, and we calculate the dispersion relation and nonlinearity (self-Kerr and cross-Kerr coefficients). To experimentally study the electrodynamics of grAl thin films, we measure microwave resonators with open-boundary conditions and test the theoretical predictions in two limits. For low frequencies, we use standard microwave reflection measurements in a low-loss environment. The measured low-frequency modes are in agreement with our dispersion relation model, and we observe self-Kerr coefficients within an order of magnitude from our calculation starting from the grAl microstructure. Using a high-frequency setup, we measure the plasma frequency of the film around 70 GHz, in agreement with the analytical prediction.