bluuebunny/crossref_metadata_2025_split huggingface dataset:
The technique of probing acceptance as a tool for teachers' professional development: A PCK study
Authors: Wiener Gerfried J. , Schmeling Sascha M. , Hopf Martin 
Published: February 2018

AbstractThis article presents a study that examined an innovative short‐term program (two sessions of 3 hr each) for the professional development of teachers. The program design is based on the technique of probing acceptance, which is aimed at investigating student learning processes. It relies on students' evaluation, paraphrasing, and adaptation of information presented during a one‐on‐one interview with defined student‐centered interview phases. During the professional development program, teachers were introduced to a novel learning unit that focuses on the subatomic structure of matter. In addition, the teachers were instructed in how to use the technique of probing acceptance during one‐on‐one interviews to evaluate the concepts of the unit. The rationale of the professional development program is that the preparation and execution of, and reflection on the one‐on‐one interviews based on the technique of probing acceptance should have an impact on dimensions of teachers' pedagogical content knowledge (PCK). Four teachers from one Austrian high school participated in this exploratory study, and each teacher conducted two one‐on‐one interviews with two different grade‐6 students. Postintervention interviews were conducted with all the teachers to document the potential influences on the teachers' PCK. The interviews were transcribed word for word, and a category‐based content analysis was applied to the transcripts. Our results indicate that during the professional development program, all the teachers revisited their existing knowledge about the subatomic structure of matter and left with an enhanced PCK, especially regarding their knowledge of learners and of instructional strategies. Overall, we show the technique of probing acceptance to be a promising tool for short‐term professional development programs, and we suggest that our findings have implications for both professional development designers and educators.
Evaluation of changes and trends in air temperature within the Southern Levantine basin
Authors: Tonbol Kareem M. , El‐Geziry Tarek M. , Elbessa Mohamed 
Published: February 2018

Based upon hourly air temperature values recorded at five coastal meteorological stations within the Southern Levantine basin during the period January 2007–December 2016, mean annual and mean monthly air temperature variations were analysed. The analysis also examined the linear trends of the mean monthly air temperature anomalies (MMATA).For the Southern Levantine basin, the results of the study revealed that 2010 was the hottest year over the region, while 2011 was the coldest. August 2015 recorded the highest mean monthly temperature over the period of investigation for the whole area of interest. January 2012, by contrast, recorded the lowest mean monthly air temperatures. This is true for all locations except Arish, which experienced its lowest mean monthly temperature record in January 2008. The results also revealed a general increasing trend in MMATA at four stations: Mersa Matruh, Ras El‐Teen, Port Said, and Arish. MMATA for Abu‐Qir appeared to be an exception with the slightly decreasing general trend.
Process discovery from event data: Relating models and logs through abstractions
Authors: van der Aalst Wil M.P. 
Published: February 2018

Event data are collected in logistics, manufacturing, finance, health care, customer relationship management, e‐learning, e‐government, and many other domains. The events found in these domains typically refer to activities executed by resources at particular times and for a particular case (i.e., process instances). Process mining techniques are able to exploit such data. In this article, we focus on process discovery. However, process mining also includes conformance checking, performance analysis, decision mining, organizational mining, predictions, recommendations, and so on. These techniques help to diagnose problems and improve processes. All process mining techniques involve both event data and process models. Therefore, a typical first step is to automatically learn a control‐flow model from the event data. This is very challenging, but in recent years, many powerful discovery techniques have been developed. It is not easy to compare these techniques since they use different representations and make different assumptions. Users often need to resort to trying different algorithms in an ad‐hoc manner. Developers of new techniques are often trying to solve specific instances of a more general problem. Therefore, we aim to unify existing approaches by focusing on log and model abstractions. These abstractions link observed and modeled behavior: Concrete behaviors recorded in event logs are related to possible behaviors represented by process models. Hence, such behavioral abstractions provide an “interface” between both of them. We discuss four discovery approaches involving three abstractions and different types of process models (Petri nets, block‐structured models, and declarative models). The goal is to provide a comprehensive understanding of process discovery and show how to develop new techniques. Examples illustrate the different approaches and pointers to software are given. The discussion on abstractions and process representations is also presented to reflect on the gap between process mining literature and commercial process mining tools. This facilitates users to select an appropriate process discovery technique. Moreover, structuring the role of internal abstractions and representations helps broaden the view and facilitates the creation of new discovery approaches.This article is categorized under:

Algorithmic Development > Spatial and Temporal Data Mining
Application Areas > Business and Industry
Technologies > Machine Learning
Application Areas > Data Mining Software Tools
A Novel Indocyanine Green Fluorescence‐Guided Video‐Assisted Technique for Sentinel Node Biopsy in Breast Cancer
Authors: Sorrentino Luca , Sartani Alessandra , Pietropaolo Gaia , Bossi Daniela , Mazzucchelli Serena , Truffi Marta , Foschi Diego , Corsi Fabio 
Published: February 2018

AbstractBackgroundThe equipment to detect indocyanine green (ICG) fluorescence for sentinel lymph node (SLN) biopsy in breast cancer is not widely accessible nor optimal. The fluorescence appears as a poorly defined white shine on a black background, and dimmed lighting is required. The aim of this study was to assess the feasibility, accuracy and healthcare costs of a novel approach for SLN biopsy by a video‐assisted ICG‐guided technique.MethodsThe technique for detecting SLN was radioisotope (RI) in 194 cases, video‐assisted ICG‐guided in 70 cases and a combined method in 71 cases. In the video‐assisted ICG group, a full HD laparoscopic system equipped with xenon lamps was used for a laser‐free detection of ICG within a colored and magnified high‐resolution image.ResultsDetection of ICG fluorescence using a laparoscope with a near‐infrared filter provided a highly defined and colored image during SLN biopsy. SLN was identified in 100% of patients in all groups. Multiple SLNs were identified in 0.5% of RI patients, in 12.9% of ICG patients and in 14.1% of ICG + RI patients (p < 0.0001). In ICG + RI group, 95.1% of lymph nodes were radioactive and 92.7% were fluorescent. Operative times and healthcare costs were equivalent between groups.ConclusionsVideo‐assisted ICG‐guided technique is a feasible and surgeon‐friendly method for SLN biopsy, with equivalent efficacy compared to RI, providing an accurate staging of the axilla.
Pulvermetallurgische Herstellung von innovativen Hochtemperaturwerkstoffen
Authors: Clemens Helmut , Mayer Svea , Heilmaier Martin 
Published: February 2018

ZusammenfassungDie pulvermetallurgische Herstellung von Bauteilen aus innovativen Werkstoffen, wie intermetallischen Titanaluminiden und Refraktärmetallsiliziden, bietet eine Vielfalt von Anwendungsmöglichkeiten in modernen Flugzeugtriebwerken und Verbrennungsmotoren. Für die Produktion von hochwertigen Legierungspulvern und deren Verarbeitung stehen mehrere industriell relevante Verfahren bereit.
Efficient single‐survey estimation of carnivore density using fecal DNA and spatial capture‐recapture: a bobcat case study
Authors: Morin Dana J. , Waits Lisette P. , McNitt David C. , Kelly Marcella J. 
Published: February 2018

AbstractPopulation density estimates are necessary to inform management and conservation, yet are difficult to obtain for cryptic species such as carnivores, and often require intensive sampling. We implemented a single‐survey, closed session, scat sampling protocol to estimate bobcat density using fecal DNA and spatial capture‐recapture at two sites over five sessions in Virginia, USA. We employed a Poisson encounter model to allow for multiple detections on scat transect segments over a single collection interval, and compared single session and multistrata (closed, multi‐site, multisession) spatial capture‐recapture (SCR) approaches to estimate density for each site and session. We found improved precision for most estimates using the multistrata SCR approach, sharing data on baseline detection and individual movement across sites and sessions. We suggest the summer session estimates are representative of the resident population, that differences in density between summer and winter are representative of potential net recruitment, and that differences between consecutive summer sessions are representative of the net recruitment realized for the population (dependent on survival and emigration). Finally, we assessed factors affecting precision in single session model estimates and provide recommendations to improve detection and reduce credible intervals that may be applicable across the bobcat range and to other carnivore species. The single survey transect methodology provides flexibility in monitoring carnivore populations specifically, or as part of concurrent monitoring for multiple carnivore species. This methodology has potential to dramatically increase the effectiveness of conservation and management dollars, improving our ability to monitor carnivore populations and assess conservation needs and actions.
A novel riboregulator switch system of gene expression for enhanced microbial production of succinic acid
Authors: Wang Jing , Wang Haoyuan , Yang Le , Lv Liping , Zhang Zhe , Ren Bin , Dong Lichun , Li Ning 
Published: February 2018

Abstract
In this paper, a novel riboregulator Switch System of Gene Expression including an OFF-TO-ON switch and an ON-TO-OFF switch was designed to regulate the expression state of target genes between “ON” and “OFF” by switching the identifiability of ribosome recognition site (RBS) based on the thermodynamic stability of different RNA–RNA hybridizations between RBS and small noncoding RNAs. The proposed riboregulator switch system was employed for the fermentative production of succinic acid using an engineered strain of E. coli JW1021, during which the expression of mgtC gene was controlled at “ON” state and that of pepc and ecaA genes were controlled at the “OFF” state in the lag phase and switched to the “OFF” and “ON” state once the strain enters the logarithmic phase. The results showed that using the strain of JW1021, the yield and productivity of succinic acid can reach 0.91 g g−1 and 3.25 g L−1 h−1, respectively, much higher than those using the strains without harboring the riboregulator switch system.
“Second‐Class Status?” Insight into Communication Patterns and Common Concerns Among Men with Hereditary Breast and Ovarian Cancer Syndrome
Authors: Suttman Alexandra , Pilarski Robert , Agnese Doreen M. , Senter Leigha 
Published: February 2018

AbstractHereditary breast and ovarian cancer syndrome (HBOC) is a cancer predisposition syndrome that affects both men and women, with more significant cancer risk elevations in women. Dissemination patterns regarding familial genetic risk information among females with HBOC are fairly well defined, but knowledge about how males share this information is limited. We interviewed 21 people primarily Ashkenazi Jewish men who were accrued via listserv email through Facing Our Risk of Cancer Empowered (FORCE). Interviews focused on family cancer history, experiences with cancer and genetic testing, motivations to pursue genetic testing and subsequently disclose genetic test results, information‐sharing patterns, health care provider response, and participants’ emotional support systems. The interviews were transcribed in their entirety, coded, and analyzed based on recurring themes. Eighteen transcripts were used for the analysis. Results were classified into five main themes. Participants (n = 8) were most concerned about cancer risk for their children and female family members, and most (n = 11) mentioned that HBOC provides them increased personal awareness, but has a negligible impact on their life overall (n = 9). Men (n = 11) were interested in a male‐focused support group to discuss HBOC and gain knowledge and information. Participants (n = 9) took on active and open communication roles with family members and health care providers. The majority of participants (n = 14) discussed the need for knowledge and awareness among the health care community and general population regarding male HBOC risks. This study serves as a pilot study and provides important and novel insights into psychosocial impacts, communication patterns, encounters with health care professionals, and expressed needs of males with HBOC.
Intentional overdose of liraglutide in a non-diabetic patient causing severe hypoglycemia
Authors: Solverson Kevin J. , Lee Holly , Doig Christopher J. 
Published: February 2018

ABSTRACTCases of liraglutide overdose are rare in the literature. Prior reports have not found hypoglycemia related to the medication overdose. We describe a case of a non-diabetic patient who intentionally overdosed on liraglutide leading to severe hypoglycemia. The patient required admission to the intensive care unit for a dextrose infusion and close monitoring. Glucagon-like protein-1 agonists are recognized for their safety and rarely causing hypoglycemia in diabetic patients. However, in this case the patient’s non-diabetic status may have put him at risk for hypoglycemia in contrast to prior cases showing no hypoglycemia in diabetic patients. The case highlights the possible dangers of liraglutide overdose and need for blood glucose monitoring in the acute presentation.
Something in the Water: Hospital Responds to Water Crisis
Authors: Redfern Roberta , Micham Jennifer , Daniels Rebecca , Childers Sue 
Published: February 2018

AbstractEarly on August 2, 2014, in the city of Toledo, Ohio, a media alert informed the public that traces of microcystin, a hazardous toxin, had been detected in the drinking water. The warning stated that residents should not drink, boil, or even touch the contaminated water. A water crisis of this magnitude was recognized to pose a potentially serious and significant impact on patient care and safety in health care environments. ProMedica Toledo Hospital’s Emergency Operation Plan addressed 3 critical issues: safe water availability, alternate cleaning solutions, and preparations for a prolonged crisis. This report details some of the lessons learned throughout the response to the crisis: particularly, because the impact was county-wide which affected other hospitals who used the same vendors, alternate water sources should have been secured in advance; the courier service was vital to delivery of supplies and moving equipment to alternate areas for sterilization processes; and finally, communication with staff and patients was jeopardized by external media outlets. Changes to the emergency plan considering these unanticipated aspects proved useful in a later incident and should be considered by all health care facilities as water emergency policies and procedures are created and reviewed. (Disaster Med Public Health Preparedness. 2018;12:666–668)
Environmental Validation of Legionella Control in a VHA Facility Water System
Authors: Jinadatha Chetan , Stock Eileen M. , Miller Steve E. , McCoy William F. 
Published: February 2018

OBJECTIVESWe conducted this study to determine what sample volume, concentration, and limit of detection (LOD) are adequate for environmental validation of Legionella control. We also sought to determine whether time required to obtain culture results can be reduced compared to spread-plate culture method. We also assessed whether polymerase chain reaction (PCR) and in-field total heterotrophic aerobic bacteria (THAB) counts are reliable indicators of Legionella in water samples from buildings.DESIGNComparative Legionella screening and diagnostics study for environmental validation of a healthcare building water system.SETTINGVeterans Health Administration (VHA) facility water system in central Texas.METHODSWe analyzed 50 water samples (26 hot, 24 cold) from 40 sinks and 10 showers using spread-plate cultures (International Standards Organization [ISO] 11731) on samples shipped overnight to the analytical lab. In-field, on-site cultures were obtained using the PVT (Phigenics Validation Test) culture dipslide-format sampler. A PCR assay for genus-level Legionella was performed on every sample.RESULTSNo practical differences regardless of sample volume filtered were observed. Larger sample volumes yielded more detections of Legionella. No statistically significant differences at the 1 colony-forming unit (CFU)/mL or 10 CFU/mL LOD were observed. Approximately 75% less time was required when cultures were started in the field. The PCR results provided an early warning, which was confirmed by spread-plate cultures. The THAB results did not correlate with Legionella status.CONCLUSIONSFor environmental validation at this facility, we confirmed that (1) 100 mL sample volumes were adequate, (2) 10× concentrations were adequate, (3) 10 CFU/mL LOD was adequate, (4) in-field cultures reliably reduced time to get results by 75%, (5) PCR provided a reliable early warning, and (6) THAB was not predictive of Legionella results.Infect Control Hosp Epidemiol 2018;39:259–266
Electronically Available Comorbid Conditions for Risk Prediction of Healthcare-Associated Clostridium difficile Infection
Authors: Harris Anthony D. , Sbarra Alyssa N. , Leekha Surbhi , Jackson Sarah S. , Johnson J. Kristie , Pineles Lisa , Thom Kerri A. 
Published: February 2018

OBJECTIVETo analyze whether electronically available comorbid conditions are risk factors for Centers for Disease Control and Prevention (CDC)-defined, hospital-onset Clostridium difficile infection (CDI) after controlling for antibiotic and gastric acid suppression therapy use.PATIENTSPatients aged ≥18 years admitted to the University of Maryland Medical Center between November 7, 2015, and May 31, 2017.METHODSComorbid conditions were assessed using the Elixhauser comorbidity index. The Elixhauser comorbidity index and the comorbid condition components were calculated using the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM) codes extracted from electronic medical records. Bivariate associations between CDI and potential covariates for multivariable regression, including antibiotic use, gastric acid suppression therapy use, as well as comorbid conditions, were estimated using log binomial multivariable regression.RESULTSAfter controlling for antibiotic use, age, proton-pump inhibitor use, and histamine-blocker use, the Elixhauser comorbidity index was a significant risk factor for predicting CDI. There was an increased risk of 1.26 (95% CI, 1.19–1.32) of having CDI for each additional Elixhauser point added to the total Elixhauser score.CONCLUSIONSAn increase in Elixhauser score is associated with CDI. Our study and other studies have shown that comorbid conditions are important risk factors for CDI. Electronically available comorbid conditions and scores like the Elixhauser index should be considered for risk-adjustment of CDC CDI rates.Infect Control Hosp Epidemiol 2018;39:297–301
A new species of the asteroid genus Betelgeusia (Echinodermata) from methane seep settings, Late Cretaceous of South Dakota
Authors: Blake Daniel B. , Halligan William K. , Larson Neal L. 
Published: February 2018

AbstractBetelgeusia brezinai new species (Radiasteridae, Paxillosida, Asteroidea) is described from diversely fossiliferous Upper Cretaceous methane seep deposits of South Dakota. Asteroids are rare at modern chemosynthetic settings, although a hydrothermal vent occurrence is known, and two possible fossil methane seep occurrences have been reported. The Radiasteridae is important to the interpretation of crown-group asteroid phylogeny. Two extant genera are assigned to the family: Radiaster is known from relatively few but geographically widely dispersed largely deeper-water settings, and Gephyreaster is uncommon over a range of depths in the North Pacific Ocean. Jurassic and Cretaceous radiasterids have been described from geographically widely separated localities. In morphological-based phylogenetic analyses, the Radiasteridae has been assigned to the order Paxillosida, and Gephyreaster is similarly placed in a molecular evaluation; Radiaster has not yet been treated in a molecular study. In molecular treatment, an approximately traditional Paxillosida is a sister taxon to a significant part of the traditional Valvatida. Comparative morphology of Mesozoic and extant asteroids enables a hypothesis for a stemward, Mesozoic paxillosidan.
DOMINIONS AND PRIMITIVE POSITIVE FUNCTIONS
Authors: CAMPERCHOLI MIGUEL 
Published: February 2018

AbstractLetA≤Bbe structures, and${\cal K}$a class of structures. An elementb∈BisdominatedbyArelative to${\cal K}$if for all${\bf{C}} \in {\cal K}$and all homomorphismsg,g':B → Csuch thatgandg'agree onA, we havegb=g'b. Our main theorem states that if${\cal K}$is closed under ultraproducts, thenAdominatesbrelative to${\cal K}$if and only if there is a partial functionFdefinable by a primitive positive formula in${\cal K}$such thatFB(a1,…,an) =bfor somea1,…,an∈A. Applying this result we show that a quasivariety of algebras${\cal Q}$with ann-ary near-unanimity term has surjective epimorphisms if and only if$\mathbb{S}\mathbb{P}_n \mathbb{P}_u \left( {\mathcal{Q}_{{\text{RSI}}} } \right)$has surjective epimorphisms. It follows that if${\cal F}$is a finite set of finite algebras with a common near-unanimity term, then it is decidable whether the (quasi)variety generated by${\cal F}$has surjective epimorphisms.