bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship of screen time with anxiety, depression, and sleep quality among adolescents: a cross-sectional study
Authors: Mohd Saat Nur Zakiah , Hanawi Siti Aishah , Hanafiah Hazlenah , Ahmad Mahadir , Farah Nor M. F. , Abdul Rahman Nur Ain Atikah 
Published: November 2024

IntroductionIn the current digital age, people’s use of electronic devices has significantly increased screen time, which may have an impact on different aspects of their lives. Adolescents today are exposed to excessive screen time, which may affect their sleep and contribute to anxiety and depression. The purpose of this study is to examine the relationship between screen time with sleep quality, anxiety and depression, among adolescents in Klang Valley, Malaysia.MethodsThis study is a cross-sectional study information was gathered from among 353 secondary school students in the Klang Valley using a questionnaire. The instrument that was used in this study was Pittsburgh Sleep Quality Index (PSQI) Malay version, screen-based media usage (SCREENS-Q) and Hopkins Symptom Check List-25 (HSCL-25) Malay version. The sampling method was stratified and convenience sampling method. The analysis study used the Smart Partial least squares (PLS) method to analyze the data.ResultsUsing the Smart PLS technique, we examined the relationship between these variables and identified revealed that screen time has a direct, positive, and significant impact on anxiety level (Mean = 0.134, β = 0.123, p &lt; 0.01) and depression levels (Mean = 0.202, β = 0.194, p &lt; 0.01). Moreover, screen time has a low effect on sleep quality (Mean = 0.128, β = 0.117, p &lt; 0.05). However, the mediating factor, sleep quality, was not significant in the indirect effect of screen time with anxiety (Mean = 0.047, β = 0.040, p  &gt; 0.05) and depression (Mean = 0.044, β = 0.043, p  &lt; 0.05).DiscussionThis study highlights the importance of understanding the association between screen use, sleep quality, anxiety and depression. Notably, excessive screen time appears to be associated with poorer sleep quality, ultimately increasing anxiety and depression. Understanding the effects of excessive screen time on sleep and well-being may have a substantial impact on public health policies and interventions. Enacting policies that promote better screen habits and sleep hygiene could improve people’s overall quality of life and well-being in the digital age. However, more longitudinal research is needed to confirm the causality of these relationships and investigate potential intervention strategies.
Implementation of tele-geriatricmental healthcare for rural veterans: factors influencing care models
Authors: Gould Christine E. , Paiko Lynsay , Carlson Chalise , Humber Marika Blair , Trivedi Ranak , Filips Julie , Savell A. Denise , Lloyd Althea , Peeples Amanda D. 
Published: November 2024

IntroductionAging rural veterans have limited access to geriatric mental health services. The establishment of Veterans Health Administration (VHA) regional telehealth hubs, or Clinical Resource Hubs (CRHs), has the potential to improve access to specialist care via telehealth delivered across healthcare systems within each VHA region. We used the Consolidated Framework for Implementation Research (CFIR 1.0) to examine variations in the tele-geriatric mental health (tele-GMH) care models being used in four CRHs.MethodsWe interviewed 11 CRH geriatric mental health providers and 12 leaders to (1) characterize the models of care, (2) identify factors in their region that support tele-GMH, (3) identify factors underlying model adaptations, and (4) learn about barriers and facilitators during implementation. The interviews were analyzed using a combination of CFIR-based coding and rapid qualitative analysis.ResultsThe services used multiple telehealth modalities; their care delivery approach ranged from consultative to continuity services. Aspects of the inner setting, specifically structural characteristics, implementation climate, and implementation readiness, influenced the model that each CRH implemented. Barriers were largely related to inner setting structural characteristics. Facilitators highlighted the importance of planning, iteration, and engaging stakeholders during implementation.ConclusionTele-GMH models varied in approach, tailoring their services to fit inner setting characteristics. Barriers and facilitators remained consistent across regions. Attending to inner setting characteristics, ongoing process improvement, and nurturing relationships with stakeholders is critical throughout the implementation of a tele-GMH program. Future research should examine the impact of the varied care delivery models on quantitative outcomes, including metrics related to access and healthcare utilization.
Incidence and risk factors for unplanned readmission after total hip arthroplasty for osteonecrosis of the femoral head
Authors: Wang Meng , Yang Xuemei , Li Junyong , Li Chengsi , Zhang Yulong , Hao Xuewei 
Published: November 2024

ObjectiveTo investigate the incidence, primary causes, and risk factors for unplanned readmissions within one year after the first primary total hip arthroplasty (THA) for osteonecrosis of the femoral head (ONFH).MethodsData were retrospectively collected from patients who had undergone the first primary THA for ONFH at two tertiary hospitals between January 2021 and December 2022, with complete 1-year follow-up assessments. Patients who experienced an unplanned readmission within 1 year were classified as the readmission group, while the others as the non-readmission group. The incidence rate and primary causes of unplanned readmission were determined, and the risk factors were identified through univariate and multivariate analyses.ResultsA total of 594 eligible patients were included, with 363 being men (61.1%) and an average age of 59.2 years at the time of surgery. Forty-seven patients were readmitted within one year, representing an accumulated rate of 7.9%. Among these, 18 (38.3%) readmissions occurred within 30 days and 27 (57.4%) within 90 days. The primary reasons for readmissions included hip dislocation (35.3%), followed by periprosthetic fracture, deep vein thrombosis, delayed incision healing, surgical site infection and others. The multivariate regression model revealed that age (every 10-year increment, OR, 1.39; 95% CI, 1.12–1.88), ARCO stage IV vs. Ⅲ (OR, 3.72; 95% CI, 1.96–7.22), CCI ≥4 vs. &lt;4 (OR = 5.49; 95% CI, 2.16–13.77), admission anemia (OR, 2.72; 95% CI, 1.37–6.83) and surgeon inexperience (OR, 2.74; 95% CI, 1.29–6.73) were significantly associated with unplanned readmission.ConclusionsThese findings provide valuable clinical insights into unplanned readmission after THA for ONFH and may aid in preoperative counselling for patients and enhance perioperative care.
RNA sequencing reveals dynamic expression of genes related to innate immune responses in canine small intestinal epithelial cells induced by Echinococcus granulosus protoscoleces
Authors: Wang Zhengrong , Pu Na , Zhao Wenqing , Chen Xuke , Zhang Yanyan , Sun Yan , Bo Xinwen 
Published: November 2024

BackgroundDogs are definitive hosts of Echinococcus granulosus, with the small intestine being the only site of parasitic infections. However, the immunomodulatory processes that occur during interactions between E. granulosus and its definitive host remain unclear. Therefore, this study aimed to evaluate gene transcription patterns in canine small intestinal epithelial cells (CIECs) following stimulation by E. granulosus protoscoleces (PSCs). Particularly, this study investigated the roles of pattern recognition receptors (PRRs), involved in recognizing pathogen-associated molecular patterns (PAMPs) and mediating the host innate immune response to the tapeworm E. granulosus.MethodsRNA sequencing (RNA-seq) was used to examine gene transcription patterns in CIECs following stimulation with PSCs for 12 and 24 h. The potential roles of differentially expressed (DE) genes were inferred through Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses.ResultsRNA-seq analysis identified 78,206,492–90,548,214 clean reads in 12 RNA samples. This included six samples stimulated with PSCs for 12 h (PSC1_12h–PSC3_12h) and 24 h (PSC1_24h–PSC3_24h) and six corresponding control samples (PBS1_12h–PBS3_12h and PBS1_24h–PBS3_24h). In the PSC_12h vs. PBS_12h and PSC_24h vs. PBS_24h groups, 3,520 (2,359 upregulated and 1,161 downregulated) and 3,287 (1765 upregulated and 1,522 downregulated) DEgenes were identified, respectively. The expression of 45 PRRs genes was upregulated in the PSC_12h and PSC_24h groups compared to those in the control groups, including 4 Toll-like receptors (TLRs), 4C-type lectin receptors (CLRs), 3 NOD-like receptors (NLRs), 17 G protein-coupled receptors (GPCRs), 4 scavenger receptors (SRs), and 13 leucine-rich repeat-containing proteins (LRRCs). GO enrichment and KEGG analyses revealed that these DEgenes were mainly involved in the regulation of host immune response processes and molecules. These included antigen processing and presentation, Th17, PI3K-Akt, Th1, and Th2 cell differentiation, neutrophil extracellular trap formation, NOD- and Toll-like receptors, TNF, intestinal immune network for IgA production and IL-17 signaling pathway. Furthermore, the identified DEgenes were involved in the regulation of signaling molecules and interaction (e.g., cell adhesion molecules and ECM-receptor interaction).ConclusionThese preliminary findings provide novel perspectives on the host innate immune response to E. granulosus PSC stimulation, with a focus on the involvement of E. granulosus-specific PRRs in host defense mechanisms against infection.
União de ensino superior da Amazônia Ocidental – UNNESA curso de medicina
Authors: Fuzari Leonardo Antunes , Rodrigues Yan Victor Roque , Carvalho Lucas Schneider de , Cezar Breno Faria 
Published: November 2024

Tendo em vista a gravidade envolvendo o câncer de mama e a importância da saúde pública promover ações para a prevenção desta doença, segue a finalidade deste estudo. Objetivo: analisar os aspectos relacionados ao controle do câncer de mama no contexto das Unidades Básicas de Saúde. Metodologia: trata-se de uma pesquisa do tipo revisão de literatura, formada por artigos científicos publicados em bases de dados online, nos últimos cinco anos, escritos nos idiomas inglês e português. Resultados e discussão: face à aplicação das estratégias de busca na SciELO e na BVS, a princípio retornaram 166 resultados, os quais passaram por filtragens conforme critérios estabelecidos previamente, para eleger 10 artigos científicos. Os dados revelam que o controle do câncer de mama em UBSs é atravessado por desafios decorrentes da ausência de investimentos na Atenção Primária em Saúde, bem como da falta de aprimoramento dos profissionais atuantes nestes núcleos. Tais condições demonstram um cenário preocupante. Considerações finais: diante do cenário encontrado, aponta-se a necessidade de se investir na educação continuada dos atuantes em unidades básicas de saúde, para que estes profissionais adquiram conhecimentos apropriados sobre os diversos aspectos do câncer de mama, bem como de demais enfermidades, visto que a Atenção Primária em Saúde é porta de acesso ao Sistema Único de Saúde (SUS).
Cambios químicos, microbiológicos y de factores de resistencia antimicrobiana en compostas de estiércol de cerdo por efecto de la relación carbono: nitrógeno
Authors: Angeles María de Lourdes , Rosales Sergio Gómez , Hernández Luis Humberto López , Andrade Laura Hernández , Mariscal-Landín Gerardo 
Published: November 2024

El objetivo fue evaluar el efecto de la relación carbono:nitrógeno (RCN) inicial (22, 26, 34 y 46) de precompostas de compostas preparadas con estiércol de cerdo sobre los cambios en el tiempo del contenido nutrimental, bacterias aerobias totales (BAT), coliformes, hongos y levaduras y factores de resistencia antimicrobiana (RAM). Se tomaron muestras para análisis químicos (días 1, 28 y 140), microbiológicos (días 1, 7, 28, 56, 84 y 140) y RAM (días 1 y 140). Los datos se analizaron mediante PROCMIX con observaciones repetidas en el tiempo y mediante análisis de regresión lineal. Los contenidos de MO, CO, N-NH4+ y RNC disminuyeron, pero el NT aumentó con el tiempo y hubo diferencias debidas a la RCN inicial en cada día de muestreo (interacción RCN inicial y día de muestreo, P<0.01). Las BAT, coliformes, hongos y levaduras también disminuyeron con el tiempo, pero fueron similares entre tratamientos al final (P<0.01). La bacteria Escherichia (E). coli se aisló en las cinco muestras iniciales de estiércol; tres cepas fueron multiresistentes a antibióticos (MMR). Al final, se redujo los aislados de E. coli por tratamiento, pero se encontró cuatro cepas MMR; además se encontró cinco cepas MMR de Citrobacter spp. La RCN inicial entre 26-34 fue más efectiva en incrementar la calidad fertilizante de los desechos porcinos; al final del estudio las compostas con RCN inicial de 22 fueron inmaduras y con RCN inicial de 46 tuvieron menos NT y mayores conteos de colifornes. Sin embargo, la RCN inicial no evitó aumento en el porcentaje de bacterias portadoras de RAM y de MMR en las compostas finales comparado con el porcentaje de estas bacterias en el estiércol inicial.
Harmonia axyridis Pallas (1773) (Cocinellidae) amplia sua distribuição geográfica, primeiro registro na Bahia, nordeste do Brasil
Authors: Soares Filho Avaldo de Oliveira , Oliveira Camila Neves de , Santos Davison Gabriel Conceição dos , Rocha Isaac Ribeiro 
Published: November 2024

Introdução: As joaninhas são Coleópteros da família Coccinellidae e são consideradas como inimigos naturais e predadoras de artrópode que são pragas urbanas e agrícolas. A Harmonia axyridis Pallas (1773) (Coccinellidae) foi introduzida para o controle biológico de insetos em vários países, mas vem invadindo várias regiões e tem se tornado uma praga em várias regiões do mundo. Metodologia: Foram feitas buscas na harborização da Universidade Estadual do Sudoeste da Bahia-UESB, Vitória da Conquista, entre 16 e 21/9/2024 e os espécimes foram coletados, identificados e depositados no Laboratório de Fitossociologia da UESB. Além da contagem populacional, foi calculada a razão sexual. Resultados: Foram encontrados 23 indivíduos e a razão sexual foi de 0,77, indicando, possivemente uma deme estabelecida. Conclusões: H. axyridis invadiu o munícipio de Vitória da Conquista, sendo o primeiro registro ocorrência da espécie na Bahia e nordeste do Brasil. Como não há dados ecológicos locais sobre a espécie futuras pesquisas devem ser realizadas, mas H. axyridis não deve ser utilizada no controle biológico de pragas na região bem como medidas sanitárias devem ser aplicadas para controlar a espécie.
Therapeutic potential of vitamin B6 in preventing hematological, biochemical, and histopathological alterations in mercury-exposed rabbits
Authors: Randa Djemil , Alima Messai , Issam Nessaibia , Fatma-Zhrra Arrouf , Samia Ati , Rayene Bouaita , Rokaya Hafi 
Published: November 2024

This study aims to examine the potential protective role of vitamin B6 against mercury-induced damage in the kidneys and thymus.
A total of a twenty-four male rabbits were evenly divided into four groups: the control group, the Hg group (0.5 g HgCl2/kg body weight), the VitB6 group (5 ppm by gavage), and the Hg + VitB6 group (0.5 g HgCl2/kg body weight + 5 ppm VitB6 by gavage) HgCl2 was included into the standard diet on a daily basis.
The results indicated that exposure to HgCl2 for thirty days resulted in an elevation of white blood cell counts, along with significant decreases in platelet, erythrocyte, haematocrit, and haemoglobin levels. Moreover, plasma levels of urea and creatinine were increased in the HgCl2 group relative to the control group. An observable elevation in kidney malondialdehyde levels was noted, associated with a reduction in reduced glutathione levels and diminished activities of glutathione peroxidase and superoxide dismutase in the HgCl2 groups. The gavage by vitamin B6, whether administered alone or combined with HgCl2, enhanced all assessed parameters. Histological evaluations of the kidneys and thymus demonstrated substantial tissue modifications in the HgCl2 group, characterised by severe glomerular atrophy, tubular necrosis, dilatation of Bowman’s capsule, thymic cortex atrophy, and lymphocyte depletion. However, rabbits administered HgCl2 and vitamin B6 had a restored histological architecture in these organs. Hgcl2 produces oxidative stress and modified biochemical markers, combined with the histological profiles of the thymus and kidneys. Nonetheless, the use of vitamin B6 has alleviated this toxicity.
ОСОБЕННОСТИ ПРАВОВОГО РЕГУЛИРОВАНИЯ ЛЕСОВ, РАСПОЛОЖЕННЫХ НА ЗЕМЛЯХ СЕЛЬСКОХОЗЯЙСТВЕННОГО НАЗНАЧЕНИЯ И КВАЛИФИКАЦИИ НЕЗАКОННЫХ РУБОК ЛЕСНЫХ НАСАЖДЕНИЙ НА ТАКИХ ЗЕМЛЯХ
Authors: Е.А. Коршунова 
Published: November 2024

После принятия в 2006 году Лесного кодекса Российской Федерации неурегулированным остался целый пласт правоотношений, касающихся вопросов использования лесных насаждений, расположенных на землях сельскохозяйственного назначения. Поскольку исчезло юридическое понятие колхозных лесов, а сами леса фактически остались никому не переданы. Кроме того, неиспользование большого количества сельскохозяйственных земель привело к их зарастанию древесными насаждениями. И визуально земельные участки, выглядящие, как лес, юридического отношения к лесу перестали иметь. В связи с чем, актуальным в 2018 году стало внесение изменений в лесное законодательство, предусматривающее порядок регулирования лесов, расположенных на землях иных категорий, не входящих в лесной фонд. Позже законодатель разработал и принял отдельный порядок использования лесов, расположенных на землях сельскохозяйственного назначения. Предусматривающий либо использование данных участков, как леса со всеми правовыми последствиями лесного законодательства, либо разработку проектов культуртехнической мелиорации и вырубку лесных насаждений на них. Но после этого возникли проблемы квалификации преступлений, связанных с незаконной рубкой лесных насаждений на таких участках.
After the adoption of the Forest Code of the Russian Federation in 2006, a whole layer of legal relations concerning the use of forest plantations located on agricultural lands remained unregulated. Since the legal concept of collective farm forests disappeared, and the forests themselves were not actually transferred to anyone. In addition, the non-use of a large number of agricultural lands led to their overgrowing with tree plantations. And visually, land plots that look like a forest, no longer have a legal relationship to the forest. In this regard, in 2018, amendments to the forest legislation became relevant, providing for the procedure for regulating forests located on lands of other categories that are not part of the forest fund. Later, the legislator developed and adopted a separate procedure for the use of forests located on agricultural lands. Providing for either the use of these areas as forests with all the legal consequences of forest legislation, or the development of land reclamation projects and the cutting of forest plantations on them. But after this, problems arose regarding the classification of crimes related to illegal logging in such areas.
Pemberdayaan Kader Dalam Edukasi Penatalaksanaan Diabetes Mellitus Pada Lansia
Authors: Dewi Mursidah , Rusmimpong Rusmimpong , Damayantie Netha 
Published: November 2024

Posyandu lansia harus memiliki kader terlatih yang peduli tumbuh aktif tanggap. Inisiatif seorang kader menjadi penting dalam melaksanakan kegiatan-kegiatan praktis sehubungan dengan meningkatkan peran serta masyarakat terutama Lansia. Dasar yang kuat untuk memaksimalkan peran kader sebagai perpanjangan tangan puskesmas dalam pelayanan langsung ke masyarakat khususnya lansia dengan Diabetes Mellitus adalah perlunya pemahaman yang cukup tentang penatalaksanaan , dan kontrol atau keteraturan aktivitas dan pengelolaan diet pada lansia, yang dapat berasal dari pemahaman orang lain tentang penyakit hipertensi maupun dari keluarga. Salah satu cara yang dapat digunakan sebagai perencanaan kegiatan perawatan kesehatan pada lansia adalah Terapi Aktivitas Kelompok (TAK). TAK merupakan suatu bentuk psikoterapi suportif berupa aktivitas-aktivitas yang membangkitkan kemandirian secara manual, kreatif dan edukasional untuk penyesuaian diri dengan lingkungan dan meningkatkan derajat kesehatan fisik dan mental lansia yang mempunyai masalah yang hampir sama. Evaluasi pengetahuan kader dalam edukasi penatalaksanaan Diabetes pada lansia melalui ketrampilan terapi aktivitas kelompok dilakukan dengan pre test dan post test. Hasil pre test kader memiliki nilai rata-rata pengetahuan 7,60 dengan hasil pretest terendah 6 dan pretest tertinggi 9. Setelah dilakukan kegiatan berupa pemberian materi dan demonstrasi TAK maka dihasilkan pengetahuan kader memiliki rata-rata 9,17. Rentang nilai terendah dan tertinggi pada saat post test juga mengalami peningkatan menjadi 8 sampai 10. Upaya pemberdayaan kader dalam berbagai aktivitas kesehatan perlu ditingkatkan dalam rangka mengembangkan dan menciptakan kader yang berkualitas, inovatif dan aktif.
Życie i dokonania arcybiskupa Jana Marii Michała Kowalskiego (1871-1942)
Authors: Przedpełski Borys , Michalski Mirosław 
Published: November 2024

Artykuł przybliża życie i działalność arcybiskupa Jana Marii Michała Kowalskiego (1871-1942), najbardziej znanego duchownego, mistyka i teologa mariawickiego, zwierzchnika niepodzielonego Kościoła mariawitów, a następnie Kościoła Katolickiego Mariawitów (grupy felicjanowskiej). Przedstawiono w nim jego postać i dzieło ze szczególnym uwzględnieniem aktywności kościelnej i społecznej w mariawityzmie. W poszczególnych częściach artykułu zostały ukazane kolejne etapy drogi życiowej Jana Kowalskiego: dzieciństwo, młodość, edukacja seminaryjna i akademicka, służba duszpasterska w Kościele Rzymskokatolickim, okoliczności i motywy wstąpienia do ruchu mariawickiego, konflikt z hierarchią rzymskokatolicką, ekskomunikowanie przez Inkwizycję Rzymską, otrzymanie sakry biskupiej od hierarchów starokatolickich w Utrechcie, zaangażowanie społeczne, reformy wprowadzane w Starokatolickim Kościele Mariawitów (1922-1935) i grupie felicjanowskiej (1935-1939), procesy i prześladowania oraz pobyt w obozie koncentracyjnym w Dachau i śmierć męczeńska w ośrodku eutanazji w Hartheim. W opracowaniu omówiono zasługi pierwszego przełożonego wyznania mariawickiego dla rozwoju organizacyjnego mariawityzmu i konflikty z przeciwnikami oraz jego główne dzieła teologiczne i przekłady literackie.