bluuebunny/crossref_metadata_2025_split huggingface dataset:
К ВОПРОСУ О ЧАСТОТЕ КЛИНИЧЕСКИХ ФОРМ МИАСТЕНИИ И ТАКТИКИ ВЕДЕНИЯ В ЗАВИСИМОСТИ ОТ ТЯЖЕСТИ ТЕЧЕНИЯ ЗАБОЛЕВАНИЯ ПО ДАННЫМ НЕВРОЛОГИЧЕСКОГО ОТДЕЛЕНИЯ ГОРОДА СЕМЕЙ
Authors: Т.В. Каймак , А.Н. Нуртасова , Н.Б. Омаров , Р.Ж. Бактыбаева , Г.А. Танышева 
Published: October 2024

Представлен анализ частоты клинических форм миастении и тактики ведения в зависимости от тяжести течения заболевания у 38 пациентов, находившихся в неврологическом отделении Медицинского Центра ГМУ города Семей в период 2013-2014 г.г. Возраст больных варьировал от 8 до 73 лет (в среднем 43,85±19,3 года), мужчин было 15 (39,5%), женщин 23 (60,5%). По клиническим проявлениям на момент поступления в стационар средняя суммарная оценка состояния силы мышц пациентов по всем группам составляла 2,1±1,8 балла. В 46,8% имело место наличие тяжелых сопутствующих заболеваний, с выраженным аутоиммунным характером поражения. Наибольшую результативность терапии показало сочетанное применение по через дневной схеме плазмафереза и Октагама, давшие улучшения состояния у 27 пациентов (71%) в виде нарастания силы по всем группам мышц на 1,5-2,5 балла.
The frequency of Myasthenia’s clinical forms and treatment tactics depending on severity of the disease in 38 patients in the neurology department of the Medical Center of Semey State Medical University during 2013-2014 was analyzed. The age of patients ranged from 8 to 73 years (at average 43.85 ± 19.3); there were 15 men (39.5%) and 23 women (60.5%). According to clinical implications at the time of admission, the average total assessment of muscle strength for all muscule’s groups was 2.1 ± 1.8 points for all patients. In 46.8% cases there was presence of serious concomitant diseases, with franked autoimmune nature of the lesion. The greatest result of therapy was received by the combined use of the scheme through daily plasmapheresis and Oktagam, which gave improvement in 27 patients (71%) with the increase of muscule’s strength in all groups of muscles at 1.5-2.5 points.
013-2014 жылдар кезеңіндегі Семей қалалық ММУ Медициналық Орталығының неврологиялық бөлімшесінде жатқан 38 науқастағы миастенияныңклиникалық формаларының жиілігінің және ауру ауырлығына байланысты жүргізу тактикасының анализі көрсетілген. Науқастардың жасы 8-ден 73-ке дейін (орташа 43,85±19,3 жас), ер адамдар 15 (39,5%), әйелдер 23 (60,5%). Стационарға түскен кездегі клиникалық көрінісі бойынша науқастардың барлық топтағы бұлшықет күшінің суммалық бағасы 2,1±1,8 балл. 46,8% науқастарда айқын аутоиммунды сипатпен ауыр қосалқы аурулар болды. Терапияның ең жақсы нәтижесін күндізгі схема бойынша плазмаферез бен Октагаманы бірге қолдану көрсетті, 27 (71%) науқаста барлық топтағы бұлшықеттердің күші 1,5-2,5 баллға жоғарылады.
КЛИНИЧЕСКИЙ СЛУЧАЙ: СИНДРОМ ПОЛАНДА
Authors: Б.Ж. Токтабаева , Н.Е. Турдина , С.К. Еленов , Г.А. Танышева , В.Е. Ли , Г.Ж. Сағындықова 
Published: October 2024

Синдром Поланда – достаточно редкий врожденный порок развития. Выявляется у одного из 30-100 тыс. новорожденных. С 1841 года по настоящее время в мире описано около 500 случаев синдрома Поланда. Возникает спорадически. Мужской пол превалирует над женским в соотношении 2–3:1. На данный момент общепринятой теорией развития синдрома Поланда является нарушение кровотока (гипоплазия) по подключичной и/или позвоночной артериям и их ветвям на 6-й неделе внутриутробного развития, которая и приводит к различным порокам развития на стороне недоразвития сосудов. В данной публикации описывается редкий клинический случай синдрома Поланда у грудного ребенка, с летальным исходом. Данные, приведенные в статье, будут полезны неонатологам, педиатрам и врачам общей практики.
Poland syndrome is a fairly rare congenital malformation. The overall incidence rate is 1 in 30,000 to 100,000 births. Since 1841 about 500 cases of Poland syndrome have been described worldwide. It often happens sporadically. Poland syndrome occurs predominantly among males at a ratio of 2-3:1 to females. Currently, the prevailing theory of the cause of Poland syndrome is the violation of blood flow (hypoplasia) of the subclavian and/or vertebral artery and their branches during the 6thweek of intrauterine development, which leads to various malformations on the side of vascular underdevelopment. This paper describes a rare clinical case of an infant with Poland syndrome with a fatal outcome. The data provided in the article will be useful for neonatologists, paediatricians and general practitioners.
Поланд синдромы - бұл өте сирек кездесетін туа біткен ақау. Ол 30-100 мың жаңа туған нәрестенің біреуінде анықталады. 1841 жылдан бастап қазіргі уақытқа дейін әлемде Поланд синдромының 500-ге жуық жағдайы сипатталған. Кейде кездеседі. 2-3:1 қатынасында еркек жынысы әйел жынысынан басым келеді. Қазіргі уақытта Поланд синдромының дамуы жалпы қабылданған теория бойынша құрсақішілік дамудың 6-шы аптасында бұғанаасты және/немесе омыртқа артериялары мен олардың тармақтары бойындағы қан ағымының (гипоплазия) бұзылуы болып табылады, бұл қан тамырларының дамымауы әсерінен әртүрлі даму ақауларына әкеледі. Бұл басылымда өмырау жасындағы балада кездескен, өліммен аяқталған Поланд синдромының сирек кездесетін клиникалық жағдайы сипатталады. Мақалада келтірілген деректер неонатологтар, педиатрлар және жалпы тәжірибе дәрігерлері үшін пайдалы болады.
Оценка возможности дооперационного прогнозирования местной распространенности первичной опухоли (рТ) у пациентов с раком желудка. Часть 1
Authors: А.И. Потейко , О.В. Красько , М.Ю. Ревтович 
Published: October 2024

Рак желудка продолжает занимать лидирующие позиции в структуре заболеваемости и смертности как в мире, так и в Республике Беларусь. Недостаточная эффективность традиционных методов обследования (КТ, ВЭГДС, ЭУС) у пациентов с раком желудка создает предпосылки для неадекватного клинического стадирования и нерационального подхода к планированию объема противоопухолевых мероприятий. В связи с этим актуальным остается поиск дополнительных предикторов степени распространенности опухолевого процесса. Целью настоящего исследования стала оценка дискриминационной способности клинико-морфологических характеристик опухолевого процесса и лабораторных показателей, определяемых в дооперационном периоде, в отношении наличия инвазии первичной опухолью серозной оболочки желудка (рТ4). В основу исследования положен ретроспективный анализ результатов лечения 1054 пациентов, радикально оперированных по поводу неметастатического рака желудка. Для оценки дискриминационной способности характеристик использован ROC-анализ. Установлено, что точность дооперационной оценки местной распространенности рака желудка в отношении дискриминации групп pT4 и pT1–3 можно повысить при комплексном учете таких признаков, как макроскопическая форма роста первичной опухоли, ее размер и особенности тканевой дифференцировки аденокарциномы, а также уровень фибриногена сыворотки.
Gastric cancer remains the leading cause of morbidity and mortality both in the world and in the Republic of Belarus. The lack of effectiveness of traditional examination methods (CT, gastroscopy, EUS) in patients with gastric cancer creates the preconditions for inadequate clinical staging and an irrational approach to treatment option. In this regard, the search for additional predictors of the prevalence of the tumor process remains relevant. The purpose of this study was to assess the discriminatory ability of the clinical and morphological characteristics of the tumor process and laboratory parameters determined in the preoperative period regarding the presence of invasion of the gastric serosa by the primary tumor (pT4). The study was based on a retrospective analysis of the results of treatment of 1054 patients undergoing radical surgery for non- metastatic gastric cancer. ROC analysis was used to assess the discriminatory ability of the characteristics. It has been established that the accuracy of preoperative assessment of the local extent of cancer in relation to discrimination between the pT4 and pT1–3 groups can be increased by comprehensively taking into account such features as the macroscopic growth form of the primary tumor, its size and features of tissue differentiation of adenocarcinoma, as well as the level of serum fibrinogen.
Disposisi, Kehendak Bebas, dan Kontingensi
Authors: Silalahi Ubat Pahala Charles 
Published: October 2024

This article discusses the long-standing philosophical challenge of integrating disposition, free will, and contingency. We place the above three realities into a coherent theoretical framework. Various disciplines have extensively studied the concepts of disposition, free will, and contingency. Nevertheless, their complex interrelationships still need to be more adequately explored. The result is a persistent dichotomy that gives rise to debates about causation, agency, and the reality of modalities. Thus, this article proposes a new framework called triadic relations to explain the mutual dependencies and emergent properties of the interaction of these fundamental ideas. The article uses a systematic synthesis approach of recent developments in dispositional essentialism, compatibilist theories of free will, and the metaphysics of the modal. We aim to show how dispositions provide the ontological foundation for free will and contingent possibilities. After all, free will operation actualizes specific potentials and introduces original novelty. This method offers an exciting resolution to the compatibilist libertarian debate by providing a new perspective on mental causation, moral responsibility, and the nature of contingency. Our findings suggest a dynamic ontology that transcends traditional philosophical categories. The findings redefine metaphysics, philosophy of mind, ethics, and interdisciplinary areas. Triadic relations emerge as a new paradigm for reconceptualizing the structure of reality and human agency to reshape the landscape of philosophical inquiry.
PEMANFAATAN TEKS SASTRA SEBAGAI UPAYA PENGUATAN PENDIDIKAN KARAKTER
Authors: Karim Ahmad Abdul , Hartati Dian 
Published: October 2024

Pemilihan bacaan sastra yang tepat dapat menjadi salah satu sandaran utama dalam proses pengembangan karakter. Mengikuti arus Revolusi Industri 4.0 karya sastra dipublikasikan dalam bentuk fisik dan digital berbasis aplikasi. Tokoh-tokoh imajiner dalam karya sastra menjadi contoh nyata bagi pengembangan karakter peserta didik. Penguatan moral dan nilai-nilai agama dalam karya sastra perlu disampaikan agar anak bangsa tidak kehilangan jati diri. Penelitian ini dilakukan untuk menyokong pendidikan agar anak bangsa cerdas berkarakter. Penelitian menggunakan metode kualitatif deskriptif. Memanfaatkan teks sastra dengan menelaah kumpulan puisi Jalan Hati Jalan Samudra karya D. Zawawi Imron, kumpulan puisi To Kill the Invisible Killer karya FX Rudy Gunawan dan Afnan Malay, kumpulan cerpen

Karpet Merah Wakil Presiden karya Abdul Kadir Ibrahim, dan naskah drama Sumur Tanpa Dasar karya Arifin C. Noer. Teknik pengumpulan data memanfaatkan teknik membaca, mencatat, dan studi pustaka terhadap narasi cerita, perilaku tokoh, dan sekuen dialog maupun monolog yang menggambarkan nilai pendidikan karakter. Data penelitian yang terkumpul, kemudian diolah melalui beberapa tahapan, meliputi: reduksi data berupa pemilihan data-data yang sesuai dengan topik penelitian, penyajian data melalui pemaknaan data-data terpilih, serta penarikan simpulan berupa tafsir data penelitian. Hasil analisis menunjukkan ketiga genre sastra memiliki nilai-nilai dalam mewujudkan penguatan pendidikan karakter di antaranya: religius, peduli lingkungan, cinta tanah air, dan nasionalis. Temuan nilai pendidikan karakter menunjukkan bahwa teks sastra penting dibaca sebagai upaya penguatan karakter di era maraknya kasus kemerosotan karakter.
Penggunaan Polietilena Glikol 6000 sebagai Flokulan Lipoprotein pada Serum Lipemik dalam Analisis Trigliserida
Authors: Wiranto Rezky Ramadhani Putri , Momuat Lidya Irma , Suryanto Edi 
Published: October 2024

ABSTRAK
Penelitian ini bertujuan untuk menentukan konsentrasi Polietilena Glikol (PEG) 6000 yang optimum dalam mengendapkan lipoprotein pada serum lipemik. Tahapan penelitian meliputi preparasi sampel, pembuatan larutan PEG berbagai konsentrasi (1%, 4%, 6% dan 8%), persiapan kuning telur ayam, puyuh, dan bebek untuk modifikasi serum lipemik, pembuatan serum lipemik yang dimodifikasi kadar trigliserida (300, 400 dan 500 mg/dL), dan penambahan PEG dalam serum lipemik. Hasil penelitian menunjukkan bahwa kadar trigliserida tertinggi terdapat pada telur ayam (2246 mg/dL), diikuti puyuh (2140 mg/dL) dan bebek (2015 mg/dL). Kadar trigliserida serum murni yang digunakan sebesar 159,6 mg/dL meningkat ketika dimodifikasi dengan penambahan kuning telur. Kadar trigliserida serum yang telah dimodifikasi terdiri atas 3 kelompok yaitu: 313,67 – 355,33 mg/dL, 419 – 454,33 mg/dL, dan 518,33 – 558,67 mg/dL. Pada kadar trigliserida 300 mg/dL konsentrasi optimal 4%, pada kadar trigliserida 400 mg/dL konsentrasi optimal 6% dan pada kadar trigliserida 8%.
Kata Kunci: Trigliserida, serum lipemik, polietilena glikol 6000

ABSTRACT
This study aimed to determine the optimum concentration of Polyethylene Glycol (PEG) 6000 in precipitating lipoproteins in lipemic serum. The stages of research included sample preparation, preparation of PEG solutions of various concentrations (1%, 4%, 6% and 8%), preparation of chicken, quail, and duck egg yolks for lipemic serum modification, preparation of lipemic serum modified triglyceride levels (300, 400 and 500 mg/dL), and addition of PEG in lipemic serum. The results showed that the highest triglyceride levels were found in chicken eggs (2246 mg / dL), followed by quail (2140 mg / dL) and duck (2015 mg / dL). The pure serum triglyceride levels used of 159.6 mg/dL increased when modified with the addition of egg yolk. Modified serum triglyceride levels consisted of 3 groups, namely: 313.67 – 355.33 mg / dL, 419 – 454.33 mg / dL, and 518.33 – 558.67 mg / dL. At triglyceride levels of 300 mg/dL the optimal concentration is 4%, at triglyceride levels of 400 mg/dL the optimal concentration is 6% and at triglyceride levels of 8%.
Keywords:. Triglycerides, lipemic serum, polyethylene glycol 6000
Low ohmic loss hybrid gap plasmonic waveguide with miniaturized metal-dielectric interface
Authors: Thi Trinh Ha , Dang Hieu Van , Van Nguyen Duong , Manh Chu Hoang 
Published: October 2024

Abstract
This study proposes a hybrid gap plasmonic waveguide (HGPW) with a miniaturized metal-dielectric interface for enhancing the propagation length of surface plasmon polaritons and to achieve an effective interaction between the hybrid gap plasmon (HGP) mode and the operating medium. The metal layer in the interface, having a good lightwave guiding property but unstable to the operating medium, is protected by a low-loss optical propagation SiO2 dielectric layer instead of a metallic layer that causes ohmic loss. The propagation length of the HGPW can be enhanced more than two orders of magnitude compared to that of the HGPW using an Au metallic protecting layer, with an expense in the mode area increase of 2.7 times. The propagation length of the device can be tuned more than 100% by modifying the refractive index of the medium surrounding the interface. This study is useful for developing active plasmonic devices such as optical modulators and sensing elements.
ДИАГНОСТИРОВАНИЕ РУЛЕВОГО УПРАВЛЕНИЯ И ПОДВЕСКИ АВТОМОБИЛЕЙ В ПРОЦЕССЕ ЭКСПЛУАТАЦИИ
Authors: А.А. Карташов , Н.В. Лимаренко , И.А. Успенский , И.А. Юхин , О.В. Филюшин 
Published: October 2024

Проблема и цель. Целью настоящего исследования было выявление метода непрерывного определения технического состояния рулевого управления и подвески в процессе эксплуатации. Методология. В процессе исследований, которые проводились в лабораторных условиях, был использован автомобиль Ford Focus 2 в качестве объекта исследования. Результаты. В результате исследования, направленного на диагностирование технического состояния рулевого управления и подвески, установлено, что использование вибрационных датчиков ДН-3-М1 и вероятностно-логистического метода позволит оценивать техническое состояние этих элементов с достаточной точностью. Заключение. Результаты исследования позволили выявить возможность использования вероятностно-логистического метода диагностирования технического состояния элементов рулевого управления и подвески.
Problem and purpose. The purpose of this study was to continuously determine the technical condition of the steering and suspension during operation. Methodology. In the course of the research, which was carried out in laboratory conditions, a Ford Focus 2 car was used as an object of research. Results. As a result of the research aimed at diagnosing the technical condition of the steering and suspension, it was found that the use of DN-3-M1 vibration sensors and the probabilistic and logistic method will allow assessing the technical condition of these elements with sufficient accuracy. Conclusion. The results of the study revealed the possibility of using a probabilistic and logistic method for diagnosing the technical condition of steering and suspension elements.
PANORAMA HOSPITALAR BRASILEIRO DOS PACIENTES INTERNADOS POR ACIDENTE VASCULAR ENCEFÁLICO NA REGIÃO SUDESTE.
Authors: Aparecida Matos Paloma , Nogueira Lopes da Silva Victória , Fontes Marietti Antonia , Teza Amanda , Queiroz Mailson 
Published: October 2024

Introdução: O acidente vascular encefálico (AVE) é a segunda maior causa de morte no mundo, além de ser a terceira principal causa de incapacidade mundialmente. Segundo a Organização Mundial de Saúde a maneira mais eficaz de reduzir a carga dos AVE é por meio da prevenção primária. Trata-se de uma afecção de grande impacto para a saúde pública, principalmente no sudeste do Brasil, considerada a região mais populosa. Objetivo: Analisar o perfil epidemiológico dos pacientes internados por AVE na região sudeste. Método: Estudo ecológico, descritivo, utilizando dados secundários com uma abordagem quantitativa, dados extraídos por meio do acesso ao Sistema de Morbidade Hospitalar. Tais dados são referentes a pacientes com AVE, não especificado como hemorrágico ou isquêmico. Resultados: O número de internações exibe um caráter crescente, com maior prevalência em Minas Gerais, seguido de São Paulo. Nota-se São Paulo e Minas Gerais com a maior parte dos valores gastos. Segunda a análise estatística, não há uma relação direta entre o sexo e a apresentação dessa afecção. A faixa etária mais acometida e com maior chance de evoluir a óbito tinha entre 60 a 79 anos. A maior taxa de mortalidade foi vista no Rio de Janeiro e em Minas Gerais. Discussão: Nossos resultados afirmam estudos anteriores que exibem uma alta prevalência de AVE em homens, fato associado a fatores de risco como alcoolismo. Além disso, o risco e a mortalidade aumentam com a idade, o envelhecimento está relacionado a comorbidades que elevam as chances de desenvolver tal patologia. Em termos de custos hospitalares, São Paulo se destaca com as maiores despesas, o que pode ser justificado pela sua infraestrutura médica avançada. Conclusão: Observa-se um número crescente de notificações, com maior prevalência em estados mais populosos e idosos, sem diferença significativa em relação ao sexo. Desse modo, o Brasil enfrenta um cenário alarmante, exigindo uma abordagem multidisciplinar e políticas públicas, afim de potencializar a promoção da saúde e redução de gastos.
APLIKASI PUPUK ORGANIK CAIR SUMBER NITROGEN DAN INTERVAL PEMBERIAN AIR PADA PERTUMBUHAN DAN HASIL TANAMAN SELADA MERAH
Authors: Mooy Lenny , Walunguru Lena , K. Remitana Yunus , Ginting Theresia 
Published: October 2024

The growth and produce of red lettuce are influenced by plant growth factors such as the availability of nutrients and water content in planting medium. This study aims to determine the growth and produce of red lettuce by using liquid organic fertilizer and watering intervals. This research employed Randomized Block Design (RBD) Factorial consisting of 12 combinations of treatments and 3 replications with the first factor tested was liquid organic fertilizer consisting of 4 levels namely: without organic liquid fertilizer; Liquid organic fertilizer from tofu pulp; liquid organic from chicken manure; and liquid organic fertilizer from lamtoro leaf. The second factor was the interval of watering: interval 1, 2, and 3 days. The parameters observed were plant height, leaf chlorophyll, wet weight, and dry weight. The results showed that the organic fertilizer treatment of tofu dregs gave the best result of plant height at 2 weeks after planting (WAP) (14.71 cm), 3 WAP (18.19 cm), 4 WAP (23.11 cm), leaf chlorophyll (21.89 mg l-1), wet weight (0.175 g), and dry weight (0.037 g). The treatment of once a day watering interval gave the best result of plant height 2 WAP (15.04 cm), 3 WAP (18.73 cm), 4 WAP (24.17 cm), leaf chlorophyll (20.68 mg l-1), Wet weight (0.183 g), dry weight (0.0038 g), while watering interval once every 3 days gave the highest water efficiency (0.026), and the treatment of liquid organic fertilizer of tofu and once a day watering interval gave the highest wet weight (0.189 g).
Impact of Open-Angle Glaucoma Severity on Vision-Related Quality of Life: A Cross-Sectional Study in a Single Center in Indonesia
Authors: Rino Agustian Praja  , Andrini Ariesti  , Hendriati  , Muhammad Hidayat  , Irayanti  , Julita  
Published: October 2024

Background: Glaucoma is a progressive optic neuropathy characterized by the gradual loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual field loss. This study aimed to investigate the relationship between the severity of primary open-angle glaucoma (POAG) and vision-related quality of life (VRQoL) in a single center in Indonesia.
Methods: A cross-sectional study was conducted at the eye polyclinic of Dr. M. Djamil General Hospital, Padang, Indonesia, from June to August 2024. A total of 54 patients with POAG were included and categorized into mild, moderate, and severe groups based on their cup-to-disc ratio and visual field index (VFI). VRQoL was assessed using the Indonesian version of the National Eye Institute Visual Function Questionnaire (NEI-VFQ 25).
Results: The mean VRQoL score was significantly lower in the severe group (60.63 ± 13.04) compared to the moderate (81.79 ± 10.42) and mild (85.04 ± 10.52) groups (p = 0.000). A strong negative correlation was observed between glaucoma severity and VRQoL (r = -0.667, p = 0.000). The social functioning subscale showed the strongest correlation with severity (r = -0.573, p = 0.000).
Conclusion: The severity of POAG significantly impacts VRQoL, with more severe disease associated with lower QoL scores. The social functioning domain appears to be particularly affected. These findings underscore the importance of comprehensive glaucoma management that addresses not only clinical parameters but also the patient's overall quality of life.