bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantification of fetal myocardial function in pregnant women with diabetic diseases and in normal controls using speckle tracking echocardiography (STE)
Authors: Rolf Nina , Kerschke Laura , Braun Janina , Falkenberg Maria Karina , Hammer Kerstin , Köster Helen Ann , Möllers Mareike , Oelmeier de Murcia Kathrin , Klockenbusch Walter , Schmitz Ralf 
Published: June 2018

Abstract

Background
The purpose of our study was to quantify the fetal myocardial function in pregnant women with diabetic diseases (FDM) and in normal controls (FC) using speckle tracking echocardiography (STE).

Methods
In this prospective study, the myocardial strain and dyssynchrony were analyzed using STE in a transversal four-chamber view in 180 fetuses (53 FDM, 127 FC) between 19 and 39 weeks of gestation. The measurements of the global and segmental longitudinal strain of both chambers (2C) and of the single left chamber (1C) were executed offline via QLab 10.5 (Philips Medical Systems, Andover, MA, USA). We assessed dyssynchrony as the time difference between peaks in strain in the mid segments of both chambers (interventricular dyssynchrony, 2C_DYS) and of the single left chamber (intraventricular dyssynchrony, 1C_DYS).

Results
Measurements were feasible with a high median frame rate of 199 frames/s (1st quartile: 174, 3rd quartile: 199). The global and segmental myocardial longitudinal strain of 2C and 1C were decreased and 2C_DYS and 1C_DYS were increased in pregnancies with diabetes compared to normal controls.

Conclusion
Our study demonstrates that fetal hearts affected by maternal diabetes mellitus (DM) show low myocardial strain values and high interventricular dyssynchrony. Two-chamber interventricular dyssynchrony has the potential to become a diagnostic marker for DM.
Experimental Study on Mechanical and Energy Properties of Granite under Dynamic Triaxial Condition
Authors: Wang Z. L. , Li H. R. , Wang J. G. , Shi H. 
Published: June 2018

Abstract
This article experimentally investigates the mechanical and energy properties of granite under dynamic triaxial loading through improved split Hopkinson pressure bar tests. These tests are conducted under five confining pressures of 0, 2.5, 5, 10, and 20 MPa. The effects of impact velocity (or strain rate) and confining pressure on stress-strain curve, dynamic strength, plastic deformation, energy dissipation, and failure mode are explored. The test results show that the dynamic strength of the granite obviously increases with the increase of confining pressure and strain rate. The plastic deformation of the granite increases, and a plastic yield platform is detected in the stress-strain curve as the confining pressure rises. The influence of strain rate on the Mohr-Coulomb criterion is mainly embodied in the cohesion, and the three-parameter Bieniawski criterion is the best to fit these experimental data. The energy evolution course is divided into four stages according to the slope of stress-strain curve. The effects of energy dissipation density and strain rate on the granite strength are similar to each other. The strain rate and energy dissipation density have a good linear relationship with the incident energy under certain confining pressure. For the same incident energy, both strain rate and energy dissipation density decrease with the increase of confining pressure. However, no clear correlation between energy dissipation rate and incident energy is observed. When the confining pressure increases from 0 to 20 MPa, the dissipation rate of energy is decreased by 62.5 %. Besides, the crack propagation velocity and the damage degree of the granite increase with the energy dissipation density, and the failure modes of the specimens change from the axial splitting to the oblique shear as confining pressure increases.
Diagnosis and Treatment of Lambl’s Excrescence on the Aortic Valve
Authors: Chong-lei Ren , Sheng-li Jiang , Rong Wang , Cang-song Xiao , Yao Wang , Chang-qing Gao 
Published: June 2018

Objective: Our objective is to summarize our experience in the diagnosis and treatment of Lambl’s excrescence (LE) on the aortic valve. Methods: The clinical data of 25 patients with LE admitted to our hospital from January 2010 to December 2014 were analyzed retrospectively. There were 17 males and 8 females, with the mean age of 55.7 ± 11.43 years (range: 30 to 70 years). Among the patients analyzed, eight also had cerebral embolism. All of the patients were diagnosed by transesophageal echocardiography (TEE). In seven cases, surgical treatment to remove the excrescence was successfully performed. Results: All 25 patients were cured and discharged. There were no complications or operative mortalities in the seven patients that underwent surgical treatment. Follow-ups were performed for all patients for an average of 2.9 ± 1.5 years. During this time, none had a new cerebrovascular accident (CVA). Conclusions: Most patients with LE are asymptomatic, though some patients showed repeated episodes of stroke. We recommend TEE as the main diagnostic means of the disease. Patients with LE that have experienced two or more CVAs or combined other heart disease and need open heart surgery should be offered surgical excision of the excrescences. Other patients should be treated conservatively with anticoagulation, or monitored closely.
Introgression of a Block of Genome Under Infinitesimal Selection
Authors: Sachdeva Himani , Barton Nicholas H 
Published: June 2018

Abstract
Adaptive introgression is common in nature and can be driven by selection acting on multiple, linked genes. We explore the effects of polygenic selection on introgression under the infinitesimal model with linkage. This model assumes that the introgressing block has an effectively infinite number of loci, each with an infinitesimal effect on the trait under selection. The block is assumed to introgress under directional selection within a native population that is genetically homogeneous. We use individual-based simulations and a branching process framework to compute various statistics of the introgressing block, and explore how these depend on parameters such as the map length and initial trait value associated with the introgressing block, the genetic variability along the block, and the strength of selection. Our results show that the introgression dynamics of a block under infinitesimal selection are qualitatively different from the dynamics of neutral introgression. We also find that, in the long run, surviving descendant blocks are likely to have intermediate lengths, and clarify how their length is shaped by the interplay between linkage and infinitesimal selection. Our results suggest that it may be difficult to distinguish the long-term introgression of a block of genome with a single, strongly selected, locus from the introgression of a block with multiple, tightly linked and weakly selected loci.
Análise socioambiental da produção de goiaba do município de Cariús (ce), Brasil.
Authors: Gomes de Sousa Sostenes , Souza da Silva Alencar Girlaine , Hermógenes de Alencar Francisco Hugo , Torres Ferreira da Costa Celme 
Published: June 2018

La revolución verde diseminada a partir de la segunda midad del siglo XX, difundió el uso de agentes químicos y máquinas pesadas en la agricultura. Los agricultores tuvieron que adecuarse a esta política de masificación de uso de agrotóxicos y fertilizantes para obtener financiamiento bancario. Son pocos los estudios que abordan el impacto generado por esta actividad; el objetivo del estudio fue levantar aspectos socioambientales de la producción de guayaba, con vistas a identificar los problemas sociambientales generados en el Municipio de Cariús (CE), Brazil. La falta de información sobre el uso apropiado de estos productos causa graves problemas en la salud, contamina la biota y a los consumidores.
Comparação entre a evolução de pré-escolares com fibrose cística identificados por triagem neonatal ou por sintomatologia clínica
Authors: Lumertz Magali Santos , De Moura Ângela , Pinto Leonardo Araújo , Camargos Paulo Augusto Moreira , Marostica Paulo José Cauduro 
Published: June 2018

AIMS: To compare clinical, laboratory and spirometric parameters of preschoolers (ages from three to six years old) with cystic fibrosis identified by abnormal newborn screening test (NS group), with data of patients whose diagnostic suspicion arose from characteristic clinical signs and symptoms (CS group).METHODS: Retrospective cohort study, with a sample obtained from the medical charts of patients who received specialized and multidisciplinary outpatient follow-up. All the included children had a confirmed diagnosis of cystic fibrosis by sweat electrolyte testing and/or genetic sequencing. Variables included sex, weight, height, body mass index, number of hospitalizations per year, Pseudomonas aeruginosa colonization, presence of pancreatic insufficiency and Shwachman score, which covers four domains: general activity, nutrition, radiological examination and physical evaluation, each one scored between 5 and 25 points. A total score ≤40 points indicates severe state, and ≥86 points indicates excellent state. For comparison of pulmonary function, data from the last spirometry performed before the age of six years were used. Outcomes were compared by chi-square or Student's t test, with a significance limit of 0.05.RESULTS: Twenty-four patients were included in the study, seven children in the NS group and 17 children in the CS group. The children of the NS group started follow-up with a mean age of 1.51±2.04 months, and those of the CS group started with 3.77±1.80 months (p=0.014). The mean Shwachman score was 94.40±2.19 in the NS vs. 87.67±8.00 in the CS group (p=0.018). The mean Z score for body mass index was 0.95±1.02 in the NS group vs. 0.51±1.05 in the CS group (p=0.051). Spirometric variables had slightly higher values in the NS group, with no statistically significant difference between groups.CONCLUSIONS: The results suggest that those patients diagnosed with cystic fibrosis from the neonatal screening test suspicion benefited from an early intervention, being able to initiate pulmonary function tests and receive treatment and counseling earlier. Evaluation of clinical parameters with the Shwachman score showed that benefits could be already observed at the preschool age.
E-Maturity in Schools / Digitalna zrelost škola
Authors: Ristic Miroslava 
Published: June 2018

AbstractThe successful integration of digital technologies in educational institutions is an imperative of any educational system in a developed society. Activities leading to the integration of digital technologies, i.e. implementation models, represent a challenge for developed countries as well as developing ones. In the European context, e-maturity in schools, is recognized as one of the key issues. The aim of this paper is to determine the indicators for assessing the level of e-maturity in Serbian schools and creating an evaluation model. In addition to a reinterpretation of the existing research and a comparative analysis, the method of modeling has been used in this paper. The proposed evaluation model can provide a basis for self-evaluation of e-maturity in schools and planning for the improvement of: digital culture at school; security and technical requirements and support; digital skills of teachers, students and employees in professional services; digital learning environment; inclusion of digital technology into the curriculum, as well as the effective implementation of digital technologies in the school organization. The evaluation model for e-maturity in schools is not only an instrument for evaluation, but also a model for effective management and decision-making. Key words: e-maturity; principal; school; student; teacher. ---SažetakUspješna integracija digitalnih tehnologija u obrazovne institucije imperativ je svakog obrazovnog sustava u razvijenom društvu. Aktivnosti koje vode do integracije digitalnih tehnologija, tj. modela implementacije, predstavljaju izazov za razvijene zemlje, kao i za one u razvoju. Pitanje digitalne zrelosti u školama, u europskom kontekstu, prepoznato je kao jedno od ključnih pitanja. Cilj je ovog rada utvrditi pokazatelje za procjenu razine digitalne zrelosti srpskih škola i stvaranje modela evaluacije. Osim reinterpretacije postojećih istraživanja i usporedne analize, u ovom se radu koristila metoda modeliranja. Predloženi model vrednovanja može pružiti osnovu za samoevaluaciju digitalne zrelosti u školama i planiranje poboljšanja digitalne kulture u školi; poboljšanja sigurnosti, tehničkih zahtjeva i podrške; digitalne vještine nastavnika, učenika i zaposlenika u stručnim službama; pružiti osnovu za digitalno okruženje za učenje; uključivanje digitalne tehnologije u nastavni plan i program, kao i osnovu za učinkovitu primjenu digitalnih tehnologija u organizaciji škole. Model ocjenjivanja digitalne zrelosti u školama nije samo instrument evaluacije već i model za učinkovito upravljanje i donošenje odluka.Ključne riječi: digitalna zrelost; ravnatelj; škola; učenik; nastavnik.
A Maçonaria no espaço insular atlântico português: As origens católicas da maçonaria madeirense
Authors: Santos Fernanda Cristina , Franco José Eduardo 
Published: June 2018

Séculos de polémicas, proibições e ataques mútuos tornaram a Maçonaria e a Igreja Católica uma espécie de adversários irreconciliáveis. Não obstante, não deixa de ser paradoxal a atração que a Maçonaria exerceu sobre membros da Igreja. Nas fileiras da maçonaria e, em particular, nos quadros das lideranças maçónicas, contaram-se membros provindos da Igreja Católica, nomeadamente do seu clero secular e regular. Se isto foi verdade a nível internacional, foi, mais ainda, de modo especial para o nosso caso de estudo, que é o arquipélago da Madeira. Como explicar esta atração e este transpor de fronteiras proibidas, mormente da parte dos católicos que aderiram à Maçonaria, continuando a sua prática católica? Ao longo deste estudo vamos tentar compreender a Maçonaria como um movimento e uma instituição, latu sensu assim definida, que procurou constituir elites com um certo nível de preparação intelectual e de influência social.
<i>Liberalismo y masonería entre Europa y América. Diego Correa (1772-1843)</i> de Manuel Hernández González
Authors: Guisado Cuellar Angel 
Published: June 2018

Reseña bibliográfica sobre Título: Liberalismo y masonería entre Europa y América. Diego Correa (1772-1843).Autor: Manuel Hernández González.Editorial: Ediciones Idea.Fecha de 1ª Edición: 2017.Lugar: Santa Cruz de Tenerife (España).ISBN: 978-84-16759-50-7Número de páginas: 245Idioma: español
Application of the Open Cycle Stirling Engine Driven with Liquid Nitrogen for the Non-Polluting Automobiles
Authors: Kravchenko M.B. 
Published: June 2018

Progress on advancing technology of using liquid nitrogen for the non-polluting automobiles is reported. It is shown that the low exergy efficiency of the known engines fueled with liquid nitrogen has discredited the very idea of a cryomobile. The design of the open-cycle cryogenic Stirling engine is proposed. This engine allows extracting up to 57% of the exergy accumulated in liquid nitrogen. The method used to calculate of such open-cycle Stirling engine is described and the calculation results and discussion are presented. It is shown that 200 liters of liquid nitrogen is sufficient for 180 km range of cryomobile at speed of 55 km/h, while a full charge of the 300-kilogram battery of Nissan LEAF electric vehicle is sufficient for a range of 160 km. Use of liquid nitrogen or liquid air as an energy vector in a transport will not require scarce materials, and, in comparison with using of lithium-ion batteries or hydrogen, this will require less capital investment.
Cooling System for Primary Low Temperature Processing and Storage of Grains of Small Frachioned
Authors: Petushenko S. 
Published: June 2018

The analysis of different aspects of grain refrigeration on elevators of Ukraine, Commonwealth of Independent States (CIS) and in the world is carried out. The advantage of the refrigeration method is shown concerning the quality and of energy conservation. A comparative analysis of various types of refrigeration machines operating on ozone-friendly refrigerants has been carried out. It is shown that it is more profitable to use heat that is worked out from refrigerating machines.
Метод визначення тепловтрат у вертикальних циліндричних ємностях на основі сумарного термічного опору тепловіддачі
Authors: Задорожный С. А. , Потапов С. Г. , Форсюк А. В. 
Published: June 2018

Розглянуто питання енергетичної ефективності одного з елементів системи теплового насосу – бака акумулятора теплової енергії. Характеристикою ефективності даного апарата являється мінімальна величина втрат тепла і для її визначення розроблена модель дослідної установки, яка дала можливість встановити емпіричну залежність. Проведений ряд досліджень для різних температурних умов навколишнього середовища та з різними варіантами конструкції установки. За отриманими даними визначено дійсні значення сумарних термічних опорів тепловіддачі та встановлено рівняння за яким їх можна визначити з мінімальною похибкою, залежно від зміни температури теплоносія, термічного опору огороджуючою конструкції ємності та температури навколишнього середовища. На основі даних отриманих з дослідної установки проведено порівняння результатів теоретичних розрахунків існуючих методик, результатів за запропонованою залежністю та дійсних даних. Проведена верифікація отриманої залежності на ємностях різних габаритів та місткості при однакових умовах роботи.
Pattern and Predictors of Outpatient Palliative Care Referral Among Thoracic Medical Oncologists
Authors: Hui David , Kilgore Kelly , Park Minjeong , Liu Diane , Kim Yu Jung , Park Ji Chan , Fossella Frank , Bruera Eduardo 
Published: June 2018

Abstract

Background
There is significant variation in access to palliative care. We examined the pattern of outpatient palliative care referral among thoracic medical oncologists and identified oncologist characteristics associated with greater referral.

Materials and Methods
We retrieved data on all patients who died of advanced thoracic malignancies at our institution between January 1, 2007, and December 31, 2012. Using median as a cutoff, we defined two groups (high-referring and low-referring oncologists) based on their frequency of referral. We examined various oncologist- and patient-related characteristics associated with outpatient referral.

Results
Of 1,642 decedents, 444 (27%) had an outpatient palliative care referral. The median proportion of referral among 26 thoracic oncologists was 30% (range 9%–45%; median proportion of high-referring 37% vs. low-referring 24% when divided into two groups at median). High-referring oncologists were significantly younger (age 45 vs. 56) than low-referring oncologists; they were also significantly more likely to refer patients earlier (median interval between oncology consultation and palliative care consultation 90 days vs. 170 days) and to refer those without metastatic disease (7% vs. 2%). In multivariable mixed-effect logistic regression, younger oncologists (odds ratio [OR] = 0.97 per year increase, 95% confidence interval [CI] 0.95–0.995), younger patients (OR = 0.98 per year increase, 95% CI 0.97–0.99), and nonmetastatic disease status (OR = 0.48, 95% CI 0.29–0.78) were significantly associated with outpatient palliative care referral.

Conclusion
The pattern of referral to outpatient palliative care varied widely among thoracic oncologists. Younger oncologists were not only referring a higher proportion of patients, but also referring patients earlier in the disease trajectory.

Implications for Practice
This retrospective cohort study found that younger thoracic medical oncologists were significantly more likely to refer patients to outpatient palliative care and to do so earlier in the disease trajectory compared with older oncologists, even after adjusting for other known predictors such as patient demographics. The findings highlight the role of education to standardize palliative care access and imply that outpatient palliative care referral is likely to continue to increase with a shifting oncology workforce.
Toponímia religiosa em Minas Gerais: os nomes dos municípios / Minas Gerais Religious Toponymy: the Names of Municipalities
Authors: Carvalho Ana Paula Mendes Alves de 
Published: June 2018

Resumo: Adotando os pressupostos teórico-metodológicos da Toponímia, este trabalho tem por objetivo apresentar um estudo toponímico dos 853 nomes de municípios de Minas Gerais, dos quais, sincronicamente, 103 – ou 12% do total – são nomes relativos à Nossa Senhora e aos santos e santas da Igreja Católica. Diacronicamente, entretanto, outros 329 municípios – 38,6% – já tiveram, ao longo de sua história, designações toponímicas dessa mesma natureza; alguns deles com mais de uma denominação como é o caso do município de Água Boa cujos topônimos anteriores já foram São José da Água Boa e Santana da Água Boa. Verificou-se, então, que os motivos para escolha do nome de um munícipio – acidente urbano –, além de observar legislação específica, pauta-se pela subjetividade coletiva e, muitas vezes, também por interesses políticos. Assim, muitos topônimos referentes aos municípios mineiros foram substituídos com o passar do tempo, sobretudo no que concerne aos mariotopônimos. Esses topônimos, no entanto, pelas reduções referentes aos títulos que acompanham a expressão Nossa Senhora, deixaram vestígios de sua origem religiosa em todo o território mineiro, o que pode ser observado pela quantidade considerável de denominações toponímicas atuais constituídas a partir dos determinantes Carmo, Conceição e Dores, por exemplo.Palavras-chave: léxico; cultura; toponímia religiosa; Minas Gerais; municípios.Abstract: Based on Toponymy theoretical and methodological assumptions, this paper aims to present a toponymic study of the 853 names of Minas Gerais municipalities, of which, synchronously, 103 - or 12% of the total - are names related to the Holy Mother (Virgin Mary) and the female and male saints of the Catholic Church. Diachronically, however, another 329 municipalities – 38,6% – have had toponymic names of this same nature throughout their history; some of them with more than one denomination as, for example, the municipality of Água Boa whose previous toponyms have been São José da Água Boa (Saint Joseph of Água Boa) and Santana da Água Boa (Saint Anne of Água Boa). It was verified, then, that the reasons for choosing the name of a municipality – an urban accident –, besides observation of specific legislations, are guided by collective subjectivity and, many times, also by political interests. Thus, many toponyms referring to the Minas Gerais municipalities have been replaced with time, especially in what mariotopônimos (names based on the names for the Virgin Mary) are concerned. These toponyms, however, due to the reductions referring to the titles that accompany the expression Holy Mother / Our Lady, left traces of their religious origin throughout all of the territory of Minas Gerais; this can be observed by the considerable amount of current toponymic denominations constituted from the determinants Carmo (Carmel), Conceição (Conception) and Dores (Sorrows), for example.Keywords: lexicon; culture; religious toponymy; Minas Gerais; municipalities.