bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antimicrobial Activity of SPC13, New Antimicrobial Peptide Purified from Scolopendra polymorpha Venom
Authors: C.I. Rodríguez-Alejandro , Gutiérrez M.C. 
Published: May 2019

Introduction:
Currently animal venoms are considered a potential source of numerous
bioactive peptides of biochemical and pharmacological interest, such as peptides with antithrombotic,
anticoagulant and antimicrobial activity.

Methods:
Such is the case of the venom from the genus Scolopendromorpha, where numerous
PAMs ranging from 2.5 to 4.4 kDa have been purified, they are broad spectrum isolates only of S.
subspinipes mutilans.

Results:
In this study, an antimicrobial peptide (SPC13) of 13 kDa, present in the venom of Scolopendra
polymorpha was purified by electroelution and presented antimicrobial activity against S.
aureus and P. aeruginosa with MIC of 45 and 192.5 μg/ml respectively, as well as bacteriostatic
activity against E. coli at a concentration of 155μg/ml.

Conclusion:
Additionally, this peptide has a 20.5% hemolytic activity. A partial sequence of
SPC13 showed 98% identity with the histone H3 reported in S. viridis (GenkBank: DQ222181.1).
Evidence on the Use of Mobile Apps During the Treatment of Breast Cancer: Systematic Review
Authors: Cruz Flávia Oliveira Almeida Marques , Vilela Ricardo Alencar , Ferreira Elaine Barros , Melo Nilce Santos , Reis Paula Elaine Diniz Dos 
Published: May 2019

Background
Cancer is a major cause of morbidity, disability, and mortality worldwide, and breast cancer is the most common cause of death in women. Different modalities of cancer treatment can have adverse effects that reduce the quality of life of patients and lead to treatment interruptions, if not managed properly. The use of mobile technologies has brought innovative possibilities for improving health care. Mobile apps can help individuals manage their own health and well-being and may also promote healthy lifestyles and information access.

Objective
The aim of this study was to identify available evidence on the use of mobile apps to provide information and facilitate communication regarding self-care management related to the adverse effects of toxicities owing to breast cancer therapy.

Methods
This systematic review includes studies which were identified using a search strategy adapted for each electronic database: CINAHL, Cochrane Library, LILACS, LIVIVO, PubMed, SCOPUS, and Web of Science. In addition, a gray literature search was performed using Google Scholar. All the electronic database searches were conducted on April 17, 2019. Two investigators independently reviewed the titles and abstracts of the studies identified and then read the full text of all selected papers. The quality of the included studies was analyzed by the Cochrane Collaboration Risk of Bias Tool and the Methodological Index for Non-Randomized Studies.

Results
A total of 9 studies which met the eligibility criteria—3 randomized clinical trials and 6 nonrandomized studies published in English from 2010 to 2018—were considered for this systematic review; 396 patients with breast cancer, as well as 40 experts in the medical and nursing fields, and 3 software engineers were included.

Conclusions
The evidence from the studies included in this systematic review is currently limited but suggests that mobile apps for women with breast cancer might be an acceptable information source that can improve patient well-being; they can also be used to report symptoms and adverse treatment-related effects and promote self-care. There is a need to test more evidence-based apps in future randomized clinical trials.
Core Data Elements in Acute Myeloid Leukemia: A Unified Medical Language System–Based Semantic Analysis and Experts’ Review
Authors: Holz Christian , Kessler Torsten , Dugas Martin , Varghese Julian 
Published: May 2019

Background
For cancer domains such as acute myeloid leukemia (AML), a large set of data elements is obtained from different institutions with heterogeneous data definitions within one patient course. The lack of clinical data harmonization impedes cross-institutional electronic data exchange and future meta-analyses.

Objective
This study aimed to identify and harmonize a semantic core of common data elements (CDEs) in clinical routine and research documentation, based on a systematic metadata analysis of existing documentation models.

Methods
Lists of relevant data items were collected and reviewed by hematologists from two university hospitals regarding routine documentation and several case report forms of clinical trials for AML. In addition, existing registries and international recommendations were included. Data items were coded to medical concepts via the Unified Medical Language System (UMLS) by a physician and reviewed by another physician. On the basis of the coded concepts, the data sources were analyzed for concept overlaps and identification of most frequent concepts. The most frequent concepts were then implemented as data elements in the standardized format of the Operational Data Model by the Clinical Data Interchange Standards Consortium.

Results
A total of 3265 medical concepts were identified, of which 1414 were unique. Among the 1414 unique medical concepts, the 50 most frequent ones cover 26.98% of all concept occurrences within the collected AML documentation. The top 100 concepts represent 39.48% of all concepts’ occurrences. Implementation of CDEs is available on a European research infrastructure and can be downloaded in different formats for reuse in different electronic data capture systems.

Conclusions
Information management is a complex process for research-intense disease entities as AML that is associated with a large set of lab-based diagnostics and different treatment options. Our systematic UMLS-based analysis revealed the existence of a core data set and an exemplary reusable implementation for harmonized data capture is available on an established metadata repository.
“O QUE AS PAREDES PICHADAS TÊM PRA ME DIZER? O QUE OS MUROS SOCIAIS TÊM PRA ME CONTAR?”: uma análise da paisagem metropolitana do Rio de Janeiro retratada nas músicas do grupo O Rappa no período de 1993 a 2003
Authors: Fulgencio Edivan Oliveira 
Published: May 2019

A partir da análise da paisagem como representação simbólica do espaço conforme proposto pela Geografia cultural, combinada à crítica dialética da Geografia Urbana, que enxerga a paisagem urbana como resultante da construção e apropriação capitalista do espaço e produto do embate histórico entre as forças envolvidas neste processo: centro x periferia; capital x trabalho; propriedade x exclusão, o presente trabalho discute a categoria geográfica paisagem, tendo como motivação e ilustração, a representação simbólica da paisagem metropolitana do Rio de Janeiro presente nas letras de canções do grupo carioca O Rappa, compostas no período de 1993 a 2003.
Palavras-chave: Geografia cultural. Paisagem urbana. Apropriação do espaço. Representação simbólica. Música.

"WHAT DO THE PAINTED WALLS HAVE TO TELL ME? WHAT DO SOCIAL WALLS HAVE TO TELL ME?": an analysis of the metropolitan landscape of Rio de Janeiro showed in the songs of the group O Rappa, between 1993 and 2003
ABSTRACT
Starting from the analysis of the landscape as a symbolic representation of the space as proposed by cultural Geography, combined with the dialectical criticism of Urban Geography, which sees the urban landscape as resulting from the capitalist construction and appropriation of the space and product of the historical conflict between the forces involved in this process : center x periphery; capital x labor; property and exclusion, the present work discusses the geographic category landscape, having as a motivation and illustration, the symbolic representation of the metropolitan landscape of Rio de Janeiro present in the lyrics of the Rio group O Rappa, composed in the period from 1993 to 2003.
Keywords: Cultural geography. Urban landscape. Appropriation of space. Symbolic representation. Music.

"¿QUÉ TIENEN LAS PAREDES PICHADAS PARA DECIRME? "¿QUÉ TIENEN LOS MUROS SOCIALES PARA CONTARME?": Un análisis del paisaje metropolitano de Río de Janeiro retratado en las canciones del grupo El Rappa en el período de 1993 a 2003
RESUMEN
A partir del análisis del paisaje como representación simbólica del espacio según lo propuesto por la Geografía cultural, combinada a la crítica dialéctica de la Geografía Urbana, que ve el paisaje urbano como resultante de la construcción y apropiación capitalista del espacio y producto del embate histórico entre las fuerzas involucradas en este proceso : centro x periferia; capital x trabajo; propiedad de exclusión, el presente trabajo discute la categoría geográfica, teniendo como motivación e ilustración, la representación simbólica del paisaje metropolitano de Río de Janeiro presente en las letras de canciones del grupo carioca O Rappa, compuestas en el período de 1993 a 2003.
Palabras clave: Geografía cultural. Paisaje urbano. Apropiación del espacio. Representación simbólica. Música.
Sowing a Seed of Safety: Providing Culturally Safe Care in Acute Care Settings for People who use Drugs
Authors: McCall Jane , Pauly Bernie 
Published: May 2019

This paper reviews the concept of cultural safety from the perspective of people who use illicit drugs and nurses in a hospital setting. Background Illicit drug use is often highly stigmatized and people who use illicit drugs often report negative healthcare experiences contributing to inequities in health and access to healthcare. Registered nurses play a key role in the delivery of healthcare when people who use drugs are hospitalized but often face difficulties in the provision of care. We explored understandings and meanings of cultural safety in healthcare as an approach to mitigate stigma and to promote health equity. Design and Methods Within an overall participatory approach to the research, we employed a qualitative ethnographic approach undertaking 275 hours of participant observation and conducting 34 open-ended interviews with 15 patients and 19 nurses on two acute care hospital units in 2012 and 2013. Result/Findings: Culturally safe care requires recognizing stereotypes and power imbalances; prioritizing trust and building relationships as important outcomes; giving patients space and time; and addressing conflicting organizational values and policies. Conclusions Providing culturally safe care requires organizational culture shifts that recognize the importance of historical, societal, and political forces that influence the way in which illicit drug use and people who use illicit drugs are constructed in society.
Assessing Family Medicine Residents’ Preparedness for the Practice of Geriatric Care
Authors: Ingram Emily , Dunkley Owen , Willoughby Karen , Yaffe Mark , Rodríguez Charo 
Published: May 2019

Introduction: Family physicians provide care to a growing and often complex group of older adults. Family medicine residencies are expected to prepare trainees to manage the medical and social needs of these seniors, but whether they feel prepared to do so is unknown. This study aimed to assess family medicine residents' sense of preparedness to address geriatric-related issues, and to identify factors that might affect this self-evaluation.
Methods: As an exploratory cross-sectional study, a 28-item questionnaire was circulated among 180 McGill University family medicine residents for voluntary completion. The survey assessed residents’ demographics, attitudes toward, and perceptions of their training in geriatrics.
Results: One hundred residents (55.5% response rate) completed the questionnaire. Residents perceived their level of preparedness increasing as they progressed in their training; however, they felt least comfortable managing behavioral problems and engaging community resources. Positive perceptions about their training for geriatric care was proportionate to the number of positive role models they had during training. Sense of preparedness was most strongly and significantly associated with the duration of exposure residents had to long-term care.
Conclusion: The aging population requires physicians who are interested in care of the elderly and who are adequately prepared through comprehensive training to care for the complex medical and social issues that affect this large segment of society. This study, through its survey of family medicine residents, provides insights about potential curriculum changes and recommendations for updating the approach to care of the elderly.
On the Compression Properties and Erosion-Corrosion Behaviour of Al 6061/15%Sicp Composite
Authors: IRFAN Osama , ALABOODİ Abdualaziz 
Published: May 2019

Aluminum alloys and composites
are used in automobile and aerospace industries due to good mechanical
properties, higher corrosion resistance and light weight. The compression test
of materials at elevated temperature is useful to study the flow stress,
workability, and the analysis of the processing conditions. In this paper, ring
specimens produced from Al 6061 /15%SiCp composite were subjected to uniaxial hot compression
tests to invistigate the deformation behavior of the material. The tests were performed
at high temperatures ranged from 300 oC to 500 °C and strain rates
of 0.008 s−1 to 2.7 s−1. The flow stress-strain curve at different
strain rates and temperatures was determined. The regression analysis was
performed to predict the flow stress during the compression test. The comparison
between the experimental and theoretical
results was also conducted. In addition, finite element method was applied to simulate and validate
the compression behavior of the composite ring. Furthermore, the
erosion-corrosion tests by slurry pot method were conducted to examine the influence
of SiC particles on erosion corrosion resistance of the material. The results showed that the flow stress of
the Al6061/15/vol.%SiCp composite is correlated directly with
temperature and strain rate. Also, the erosion corrosion resistance increased
with adding SiC particles to Al 6061 alloy.
KONSEP EKOLOGIS PADA PERMUKIMAN SUKU LAWALU DI KAMANASA KABUPATEN MALAKA, NUSA TENGGARA TIMUR
Authors: Bebhe Kristiana , Daton Richardus , Lake Reginaldo Christophori , Lapenangga Apridus 
Published: May 2019

Abstract: Kamanasa Village in Malaka Regency is a vernacular village inherited based on the knowledge and local wisdom of the Lawalu tribe. Kamanasa people obey traditions and customs for obedience to tribal ancestors. The concept of obedience arises in settling cultures, in village spatial planning and residential and material use. The architectural concepts that exist in the village of Kamanasa have ecological characteristics in the form, structure and use of materials, also in the behavior of the Kamanasa people. This study focuses on identifying the economic concepts of Kamanasa vernacular architecture and how the sustainability of ecological concepts is maintained. Field observations and literature studies of ecological design principles were used in this study. The results of the study showed that the vernacular village of Kamanasa applied an ecological concept of architecture in accordance with the principles of ecological design that were inherited through the tradition of building houses, linkages with the environment, and social relations in mutual cooperation. The Kamanasa vernacular village is still supported by aspects of traditional beliefs and norms, so the ecological concept of the Kamanasa vernacular architecture deserves to be an ecological concept of cultural architecture.Keywords: Ecological, Vernacular Architecture, Kamanasa VillageAbstrak: Desa Kamanasa di Kabupaten Malaka merupakan desa vernakular yang diwarisi berdasarkan pengetahuan dan kearifan lokal suku Lawalu. Orang Kamanasa taat tradisi dan adat istiadat demi ketaatan terhadap leluhur suku. Konsep ketaatan muncul pada budaya bermukim, pada tata keruangan desa dan rumah tinggal maupun penggunaan material. Konsep berarsitektur yang ada pada desa Kamanasa memiliki ciri-ciri ekologis pada tata bentuk, struktur dan penggunaan material, juga pada perilaku orang Kamanasa. Kajian ini berfokus pada identifikasi konsep eklogis arsitektur vernakular Kamanasa dan bagaimana keberlanjutan konsep ekologis dipertahankan. Observasi lapangan dan kajian pustaka prinsip-prinsip desain yang ekologis digunakan dalam penelitian ini. Hasil penelitian menunjukkan, desa vernakular Kamanasa menerapkan konsep ekologis arsitektur sesuai dengan prinsip-prinsip desain ekologis yang diwariskan melalui tradisi membangun rumah, keterkaitan dengan lingkungan, dan hubungan sosial bergotong royong. Desa vernakular Kamanasa masih didukung oleh aspek kepercayaan dan norma-norma adat, sehingga konsep ekologis arsitektur vernakular Kamanasa layak dijadikan konsep arsitektur kiwari yang ekologis. Kata kunci: Ekologis, Arsitektur Vernakular, Desa Kamanasa
Ordinal Logistic Regression with an Application to Health Service Quality in Raden Mattaher Jambi Hospital
Authors: Pasaribu Feri Tiona , Mardia Ainun , Sormin Corry 
Published: May 2019

Health care is a treatment received by the community provided by health workers. The quality of health services will provide satisfaction to health services. Service actions that affect the value of satisfaction are availability and completeness of facilities, physical evidence of administration, reliability of officers, responsiveness of officers, guarantees received by patients and families of patients, and empathy felt by patients. This level of satisfaction assessment is in the form of an ordinal scale that is not satisfied, less satisfied, satisfied and very satisfied. The analysis used to determine the level of satisfaction is by ordinal logistic regression analysis. The sample used in this study is the patient or family of patients at Raden Mattaher Hospital. The stages of data analysis used are the validity and reliability test, parameter estimation, model feasibility test, parameter significance test and the best model selection. The results of the analysis obtained the best models and with factors that influence the level of quality of health services at Raden Mattaher Hospital, namely physical evidence, availability and completeness of facilities and responsiveness.
Surgical treatment of spontaneous endometriosis in rhesus macaques (Macaca mulatta): 11 cases (2007–2011)
Authors: Kennedy Lucy H. , Nowland Megan H. , Nemzek-Hamlin Jean A. 
Published: May 2019

Abstract
OBJECTIVE To determine long-term outcome for rhesus macaques (Macaca mulatta) with endometriosis that underwent surgical treatment and identify factors potentially associated with long-term outcome.
DESIGN Retrospective case series.
ANIMALS 11 female rhesus macaques.
PROCEDURES Medical records of female rhesus macaques in which endometriosis was diagnosed between 2007 and 2011 and that underwent abdominal exploratory surgery were reviewed.
RESULTS In 5 macaques, the only clinical abnormality was a caudal abdominal mass identified during a routine physical examination, and in 6 macaques, overt clinical signs of endometriosis, including anorexia, dysmenorrhea, and lethargy during menses, were reported. Five macaques had histologically confirmed complete ovarian removal, and another 5 had incomplete ovarian removal (ovarian tissue was not examined histologically in 1 macaque). Nine animals survived at least 12 months after surgery, and 6 survived at least 60 months after surgery. Macaques that did not have overt clinical signs were significantly more likely to survive at least 60 months after surgery. However, extent of ovarian removal was not significantly associated with survival 12 or 60 months after surgery.
CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that, in select situations, surgery (ovariectomy or ovariohysterectomy) may be curative in macaques with endometriosis and may result in long-term survival. Further, findings suggested that monitoring until clinical signs appear before performing surgery is not warranted in adult female macaques suspected to have endometriosis that only have a caudal abdominal mass and no other overt clinical signs.
CORPO FEMININO, CORPO POLÍTICO: DE FUSTIGADO À DEVORADOR DO INSTITUÍDO
Authors: Colling Ana Maria , Acom Ana Carolina 
Published: May 2019

Escrever sobre corpo feminino e moda é escrever sobre consentimentos e transgressões. De um corpo construído historicamente, alvo e efeito de artefatos culturais e pedagógicos para um corpo político. Corpo que sempre foi motivo de suspeitas, centro de relações saber/poder. A questão do aborto, sua descriminalização, está no centro dos debates, a quem pertence este corpo. “Meu corpo me pertence” foi palavra de ordem no movimento feminista, que balançou o mundo nas décadas de 60/70 e continua sendo o mote dos novos movimentos feministas, como a Marcha das Vadias. A moda se constitui em um corpo que é lido pelo que veste ou despe. O campo da Moda além do consumo e mudanças, se refere a qualquer relação de um corpo vestido ou adornado, ou na ausência de vestes (o corpo desnudo), e ainda, a vestes sem corpos. Mesmo em povos sem roupas encontramos adornos, apêndices corporais utilitários ou pinturas simbólicas da pele. Dessa maneira podemos pensar o corpo feminino como resistência e máquina de guerra: a nudez em performances artísticas contemporâneas, a expressividade política de manifestações, assim como em corpos trans, sem definições, mas constituindo estéticas que compõem outros modos de existência. O corpo presente na Marcha das Vadias é subversivo, está ali como máquina de guerra: peitos à mostra ou mensagens pintadas que o vestem. A estética da mulher trans ou de uma dragqueen rompe com a expectativa do gênero designado àquele indivíduo, e será através da Moda que essa construção de um novo corpo tomará forma.
The active turn in Danish welfare policy:
Authors: Abrahamson Peter 
Published: May 2019

Flexicurity is viewed as the best way of securing both a good investment environment and a secure workforce. Flexicurity combines a flexible labor market, where employers have few or no restrictions with regard to firing workers, with generous welfare benefits; and the two are facilitated through active labor market policies. Denmark really has a flexible labor market; but benefits in case of unemployment and activation cannot be described as generous in a European context. Activation is often perceived as a punishment for being unemployed and has mainly been undertaken because it is mandatory, and one is in risk of losing benefits if one refuses an activation offer. There is a price to be paid for a high degree of flexibility, and it comes in the form of marginalization and exclusion. 25 percent of the Danish population of working ages is for long spells or permanently existing on not very generous benefits outside the labor market.