bluuebunny/crossref_metadata_2025_split huggingface dataset:
Suilloid fungi as global drivers of pine invasions
Authors: Policelli Nahuel , Bruns Thomas D. , Vilgalys Rytas , Nuñez Martin A. 
Published: December 2018

SummaryBelowground biota can deeply influence plant invasion. The presence of appropriate soil mutualists can act as a driver to enable plants to colonize new ranges. We reviewed the species of ectomycorrhizal fungi (EMF) that facilitate pine establishment in both native and non‐native ranges, and that are associated with their invasion into nonforest settings. We found that one particular group of EMF, suilloid fungi, uniquely drive pine invasion in the absence of other EMF. Although the association with other EMF is variable, suilloid EMF are always associated with invasive pines, particularly at early invasion, when invasive trees are most vulnerable. We identified five main ecological traits of suilloid fungi that may explain their key role at pine invasions: their long‐distance dispersal capacity, the establishment of positive biotic interactions with mammals, their capacity to generate a resistant spore bank, their rapid colonization of roots and their long‐distance exploration type. These results suggest that the identity of mycorrhizal fungi and their ecological interactions, rather than simply the presence of compatible fungi, are key to the understanding of plant invasion processes and their success or failure. Particularly for pines, their specific association with suilloid fungi determines their invasion success in previously uninvaded ecosystems.
Having the right neighbors: how tree species diversity modulates drought impacts on forests
Authors: Grossiord Charlotte 
Published: December 2018

SummaryDroughts are a rising concern for terrestrial ecosystems, particularly for forests where drought‐induced reductions in tree growth and survival are reported. Biodiversity has long been acknowledged as an important component modulating ecosystem functions, including mitigating their vulnerability to climate‐related stresses. Yet the impact of tree diversity on forest vulnerability to drought is unclear. In this review, consistent mechanisms are identified by which tree diversity could reduce vulnerability to drought and emerging evidence is revealed that tree diversity is not systematically positively related to drought resistance in forests. A path is suggested to further increase our knowledge on this subject in the face of climate change, proposing standardization of methods to quantitatively establish diversity impacts on the drought resistance of forests.
Photostability of Terbinafine Under UVA Irradiation: The Effect of UV Absorbers
Authors: Kryczyk‐Poprawa Agata , Żmudzki Paweł , Koczurkiewicz Paulina , Pękala Elżbieta , Hubicka Urszula 
Published: December 2018

AbstractThe photostability of drugs administered topically on unprotected skin is a complex phenomenon that could be connected with the loss of activity or, rather rarely, the occurrence of toxic degradation products. In this study, an in‐depth investigation of the photostability of terbinafine, in both solutions and formulations, was conducted, taking into account the presence of UV absorbers such as TiO2, ZnO, avobenzone, 3‐(4‐methylbenzylidene)camphor, octocrylene, benzophenone‐1 and benzophenone‐2. The clear photocatalytic degradation of terbinafine in ethanol solution was observed in the presence of TiO2 and/or ZnO. In other cases, terbinafine was stable, with the exception of, in the presence of octocrylene. The presumed degradation products of terbinafine were identified for the first time using LC/MS/MS, and transformation pathways were proposed. In the case of a cream formulation, the percentage of initial terbinafine content was almost unchanged in the presence of the UV absorbers benzophenone‐1, benzophenone‐2 and 3‐(4‐methylbenzylidene)camphor. In vitro cytotoxicity risk assessment of terbinafine based on photostability under UVA irradiation was evaluated using the human skin fibroblast BJ (ATCC® CRL‐2522™), and this showed no statistically significant difference in cell viability for all samples analyzed.
Patterns of Local Policy Disruption: Regulatory Responses to Uber in Ten North American Cities
Authors: Spicer Zachary , Eidelman Gabriel , Zwick Austin 
Published: December 2018

AbstractSince its inception in 2009, Uber has grown into a technology behemoth, with operations in over 70 countries and 500 cities around the world. Along the way, it has successfully forced regulatory upheaval in hundreds of local taxi markets controlled by municipal authorities. In this sense, Uber is not only a market disruptor, but also a policy disruptor. This paper examines the nature of such policy disruption at the local level by reviewing regulatory responses to Uber in ten North American cities. We find that regulatory outcomes are a function of two factors: Uber’s government relations strategy, either cooperative or confrontational, and the degree to which local governments perceive Uber as complementary or harmful to the existing marketplace. We conclude by proposing a typology of regulatory responses to Uber as a basis to identify patterns in the behavior of municipal regulatory authorities and political leaders.
Cytokine, glycemic, and insulinemic responses to an acute bout of games‐based activity in adolescents
Authors: Dring Karah J. , Cooper Simon B. , Morris John G. , Sunderland Caroline , Foulds Gemma A. , Pockley A. Graham , Nevill Mary E. 
Published: December 2018

An acute bout of endurance exercise in adults stimulates a same‐day anti‐inflammatory response which may affect low‐grade chronic inflammation and insulin resistance and benefit cardio‐metabolic health. The anti‐inflammatory responses to intermittent games‐based exercise and to exercise in young people beyond 2 hours post‐exercise are unknown. Thus, the purpose of the present study is to examine the anti‐inflammatory, glycemic and insulinemic response to games‐based activity in adolescents. Following ethical approval and familiarization, 39 adolescents (12.3 ± 0.7 years) completed an exercise (E) and rested (R) trial in a counterbalanced, randomized crossover design. Following a standardized breakfast, participants completed 1‐hour games‐based activity. Capillary blood samples were taken at baseline, immediately and 1 hour post‐exercise, and 30, 60 and 120 minutes following a standardized lunch. A final blood sample was taken the next morning. Data were analyzed using repeated measures ANOVA. IL‐6 concentration was higher on day one of the exercise trial (E:3.4 ± 0.4, R:2.7 ± 0.4 pg/mL; P = 0.006), as was the anti‐inflammatory IL‐6:TNF‐α ratio (E:5.53 ± 0.93, R:3.75 ± 0.45; P = 0.027). Levels of the anti‐inflammatory cytokine IL‐10 increased on day two of the exercise trial (E:2.11 ± 0.23, R:1.66 ± 0.16 pg/mL; P = 0.032). Insulin sensitivity was enhanced on the exercise trial with a reduction in iAUC following the standardized lunch (E:2310 ± 834, R:3122 ± 1443 mU/L × 120 minutes; P < 0.001). Games‐based activity stimulated an anti‐inflammatory response up to 24 hours post‐exercise and improved insulin sensitivity in response to a standardized meal in healthy adolescents. These novel findings suggest that games‐based activity is an ecologically valid mode of exercise to elicit beneficial effects on cardio‐metabolic risk factors in young people.
Concurrent associations between mothers’ references to internal states and children’s social understanding in middle childhood
Authors: Paine Amy L. , Hashmi Salim , Roberts Siwan , Fyfield Rhiannon , Hay Dale F. 
Published: December 2018

AbstractAlthough it is well established that features of maternal speech are associated with children’s social understanding in the preschool years, few studies explore this relationship in middle childhood. Within the context of a prospective longitudinal study of a representative community sample of families (subsample n = 207, mean age = 82.88 months), we investigated concurrent associations between mothers’ internal state language and aspects of 7‐year‐olds’ social understanding, including children’s understanding of belief and spontaneous references to internal states during free play. When sociodemographic, maternal, and child characteristics were controlled, mothers’ references to their own cognitions were associated with dimensions of children’s social understanding. Our findings suggest that exposure to others’ perspectives contributes to children’s advanced understanding of minds, which has implications for interventions that foster social understanding.
Romantic partner satisfaction among low‐income mothers: Links to child‐peer and teacher relationships via mother‐child conflict
Authors: Weaver Krug Chelsea M. , Taraban Lindsay , Shaw Daniel S. , Dishion Thomas J. , Wilson Melvin N. 
Published: December 2018

AbstractThe current project explores maternal inter‐parental (IP) romantic partner satisfaction in relation to mother‐child conflict and later peer and teacher relations from early to middle childhood among a sample of low‐income, ethnically diverse mothers (N = 271) who were part of a longitudinal study testing the effectiveness of the Family Check‐Up intervention. We hypothesized spillover effects from IP dissatisfaction during early childhood to mother‐child conflict two years later. Greater mother‐child conflict in turn was expected to lead to poorer peer relations and greater conflict with teachers in middle childhood. The results support a spillover effect from lower IP satisfaction at age 3 to higher mother‐child conflict at age 5 to poorer peer relations and greater conflict with teachers at school at ages 8.5, 9.5, and 10.5. Mother‐child conflict significantly mediates these pathways. The results support the importance of IP satisfaction and mother‐child conflict in early childhood as critical factors in pathways leading to low‐income children's social relationships at school during middle childhood.
Coproduction and the third sector in France: Governmental traditions and the French conceptualization of participation
Authors: McMullin Caitlin 
Published: December 2018

AbstractResearch on coproduction has tended to assume a coherence of conceptualizations of coproduction across borders, and little analysis of the framing and discourse of coproduction in different contexts has been undertaken. In the French language literature on citizen participation and the social and solidarity economy, the term coproduction is little used. This paper investigates the narratives of French academics, public, and third sector actors in order to identify what, if anything, is different about the French context that explains this gap. Drawing on semistructured interviews, I identify four key narratives that distinguish the French conceptualizations of coproduction and the third sector from the dominant English language coproduction literature: (a) a mainstreaming of coproduction as part of organizational purpose in the social and solidarity economy, (b) an emphasis on formalized involvement of citizens in organizational governance, (c) the motivation of citizen empowerment and democracy over cost and efficiency, and (d) the use of the term coconstruction rather than coproduction. I argue that these narratives are shaped by the governmental traditions of France, which emphasize formal rules, hierarchy, representative democracy, and a suspicion of particularistic interests. I conclude by questioning the universality of some of the axioms of coproduction theory in the English language literature.
A survey of infectious diseases and vaccination uptake in long‐term hematopoietic stem cell transplant survivors in Australia
Authors: Dyer Gemma , Gilroy Nicole , Brice Lisa , Kabir Masura , Gottlieb David , Huang Gillian , Hogg Megan , Brown Louisa , Greenwood Matt , Larsen Stephen R. , Moore John , Hertzberg Mark , Tan Jeff , Ward Christopher , Kerridge Ian 
Published: December 2018

AbstractBackgroundThis cross‐sectional survey aimed to establish the prevalence of infectious diseases and vaccination uptake in long‐term allogeneic hematopoietic stem cell transplants (HSCT) survivors in New South Wales, in order to reduce long‐term post‐HSCT morbidity and mortality and enhance long‐term care.Patients and methodsHematopoietic stem cell transplants survivors aged over 18 years and transplanted between 2000‐2012 in New South Wales (NSW) were eligible to participate. Survivors self‐completed the Sydney Post BMT Study survey, FACT‐BMT (V4), Chronic Graft versus Host Disease (cGVHD) Activity Assessment Self Report, Lee Chronic GvHD Symptom Scale, DASS21, Post Traumatic Growth Inventory, and the Fear of Recurrence Scale.ResultsOf the 583 HSCT survivors contacted, 441 (78%) completed the survey. Respondents included 250 (57%) males and median age was 54 years (range 19‐79 years). The median age at the time of transplant was 49 years (Range: 17‐71), the median time since HSCT was 5 years (Range: 1‐14) and 69% had cGVHD. Collectively, 41.7% of survivors reported a vaccine preventable disease (VPD) with the most common being influenza‐like‐illness (38.4%), varicella zoster/shingles (27.9%), pap smear abnormalities (9.8%), pneumococcal disease (5.1%), and varicella zoster (chicken pox) (4.6%). Only 31.8% had received the full post‐HSCT vaccination schedule, and the majority (69.8%) of these had received the vaccines via their General Practitioner. cGVHD was not found to be a significant factor on multivariate analysis for those who were vaccinated. There was a trend toward lower vaccination rates in patients in a lower income strata.ConclusionsVaccinating post‐HSCT survivors to prevent infections and their consequences have an established role in post‐HSCT care. Improving rates of post‐HSCT vaccination should be a major priority for BMT units.
A case of Verruconis gallopava infection in a heart transplant recipient successfully treated with posaconazole
Authors: Moran Conor , Delafield Nathan L. , Kenny Grace , Asbury Kara L. , Larsen Brandon T. , Lambert Karen L. , Patron Roberto L. 
Published: December 2018

AbstractVerruconis gallopava is an environmental dematiaceous fungus that is recognized increasingly as a cause of human disease, especially for immunocompromised persons. Infection can range from superficial and localized lesions to pulmonary involvement and disseminated disease, including central nervous system abscesses. Optimal therapy is undefined. We report a patient post cardiac transplant who had pulmonary infection with V gallopava and was treated successfully with posaconazole.
Molecular phylogeny and hemipenial diversity of South American species ofAmerotyphlops(Typhlopidae, Scolecophidia)
Authors: Graboski Roberta , Arredondo Juan C. , Grazziotin Felipe G. , da Silva Ariane A. A. , Prudente Ana L. C. , Rodrigues Miguel T. , Bonatto Sandro L. , Zaher Hussam 
Published: December 2018

AbstractTyphlopidae is the most diverse family of Scolecophidia, with 269 species.Amerotyphlopswas recently erected within subfamily Typhlopinae and comprises fifteen species distributed from Mexico to Argentina and the southern Lesser Antilles. Despite recent advances, affinities among typhlopines remain poorly explored, and the phylogenetic relationships and morphology of the South American (SA) species were never accessed before. Here, we performed a phylogenetic analysis including 106 species of Typhlopidae and ten genes. Our dataset represents the most comprehensive for SA species, containing seven of eight recognized species. Corroborating previous studies, we recovered the main groups of Typhlopoidea, and for typhlopines, we recovered with strong support two clades: (a) the Greater Antilles radiation, and the (b) Lesser Antilles and SA radiation. Within the SA radiation, we recovered four main lineages: (a) a clade formed byA. tasymicrisandA. minuisquamus; (b) a clade composed byA. reticulatusas the sister group of all other SA species; (c) a clade composed byA. brongersmianusas the sister group of a clade comprising all Northeast Brazilian Species (NBS); and (d) a clade of the NBS, includingA. yonenagae,A. arenensis,A. paucisquamus,andA. amoipira. We supplemented our phylogenetic result with the description of hemipenial morphology for seven SA species and comment their relevance to the systematics of Typhlopinae. Hemipenes of SAAmerotyphlopsfollow the general pattern in scolecophidians (single organ with undivided sulcus). OnlyA. reticulatusandA. minuisquamushave organs with calcified spines. According to our results, hemipenial ornamentation have shown highly informative and could represent a potential source of systematic and taxonomic characters in that group. We also present an extensive review of the geographical distribution for all SA species. Our study represents the first integrative analysis of a poorly known evolutionary radiation of one of the most widespread SA fossorial snakes.
Neutrinoless double beta decay in minimal left–right symmetric model with universal seesaw
Authors: Borah Debasish , Dasgupta Arnab , Patra Sudhanwa 
Published: December 2018

We present a detailed discussion on neutrinoless double beta decay [Formula: see text] within left–right symmetric models based on the gauge symmetry of type [Formula: see text] as well as [Formula: see text] where fermion masses including that of neutrinos are generated through a universal seesaw mechanism. We find that one or more of the right-handed neutrinos could be as light as a few keV if left–right symmetry breaking occurs in the range of a few TeV to 100 TeV. With such light right-handed neutrinos, we perform a detailed study of new physics contributions to [Formula: see text] and constrain the model parameters from the latest experimental bound on such a rare decay process. We find that the new physics contribution to [Formula: see text] in such a scenario, particularly the heavy–light neutrino mixing diagrams, can individually saturate the existing experimental bounds, but their contributions to total [Formula: see text] half-life cancel each other due to unitarity of the total [Formula: see text] mass matrix. The effective contribution to half-life therefore, arises from the purely left and purely right neutrino and gauge boson mediated diagrams. We find that the parameter space saturating the [Formula: see text] bounds remains allowed from the latest experimental bounds on charged lepton flavor violating decays like [Formula: see text]. We finally include the bounds from cosmology and supernova to constrain the parameter space of the model.
Preparation of Ag-decorated TiO2 nanotube electrode and its catalytic property
Authors: Yue Xiaoyu , Manach Andrea , Dong Junzhe , Gao Wei 
Published: December 2018

Novel Ag/TiO2 nanotubes electrode has been synthesized by successive ionic layer adsorption reaction (SILAR) using TiO2 nanotubes as the catalyst support. Scanning electron microscopy and energy dispersive spectroscopy analysis show that Ag nanoparticles have been successfully deposited on the top of TiO2 nanotubes. The Ag/TiO2 nanotubes electrode has a superior electro-catalytic property for hydrazine oxidation with a low onset potential and high current density. The result indicates that Ag/TiO2 nanotube electrode has a potential application for hydrazine sensor and hydrazine fuel cell.
Biomarkers for Immunotherapy Toxicity: Are Cytokines the Answer?
Authors: Johnson Douglas B. , Balko Justin M. 
Published: December 2018

Abstract
Immune checkpoint inhibitors induce durable responses in some patients with advanced cancer but may simultaneously trigger autoinflammatory immune-related adverse events (irAE). The pathogenesis of irAEs may relate to genetic predisposition, environmental insults, or tumor–host interactions. Elevated expression of certain cytokines may signal subclinical inflammation that evolves into severe irAEs with treatment.
See related article by Lim et al., p. 1557
Germline Variant in SLCO2B1 and Response to Abiraterone Acetate Plus Prednisone (AA) in New-onset Metastatic Castration-resistant Prostate Cancer (mCRPC)
Authors: Hahn Andrew W. , Gill David M. , Poole Austin , Nussenzveig Roberto H. , Wilson Sara , Farnham James M. , Stephenson Robert A. , Cannon-Albright Lisa A. , Maughan Benjamin L. , Agarwal Neeraj 
Published: December 2018

Abstract
There are many treatment options available for men with metastatic castration-resistant prostate cancer (mCRPC). Yet, biomarkers predictive of differential response to treatment are currently unavailable. A recent translational study suggested that SLCO2B1 genotype could predict response to abiraterone acetate for men with advanced prostate cancer. Here, we investigate whether germline variants in SLCO2B1 are predictive of response to first-line abiraterone acetate in men with new mCRPC. Clinical data and samples were analyzed from a prospective prostate cancer registry at the University of Utah (Salt Lake City, UT). Genotyping was performed using the Illumina OmniExpress genotyping platform. Primary endpoint was progression-free survival (PFS) on first-line abiraterone acetate in men with mCRPC. We performed a prespecified multivariate Cox regression analysis to assess the independent predictive value of rs12422149 and rs1789693 on PFS on abiraterone acetate. Of 401 men with advanced prostate cancer genotyped, 323 were homozygous wild-type for rs12422149 (80.5%), 74 were heterozygous (18.5%), and 4 were homozygous variant (1.0%). In a multivariate analysis of 79 men treated with first-line abiraterone acetate for mCRPC, men heterozygous for rs12422149 had significantly improved median PFS compared with the homozygous wild-type group (8.9 months vs. 6.3 months; HR, 0.46; 95% confidence interval, 0.23–0.94; P = 0.03). No significant difference in median PFS was seen by rs1789693 genotype. In this first clinical validation of translational data reported by Mostaghel and colleagues, germline variant alleles in rs12422149 of SLCO2B1 are common and predict improved response to first-line abiraterone acetate in men with mCRPC.
BrasilGaliza: Ensinar literatura brasileira na Galiza, algumas considerações
Authors: Rangel Vivian 
Published: December 2018

Este artigo apresenta considerações sobre o ensino de literatura e culturas brasileiras na Galiza, a partir da experiência de um Leitor brasileiro na Faculdade de Filologia da Universidad de Santiago de Compostela (USC). Há 20 anos a USC conta com professores brasileiros que devem repensar estratégias didáticas para ensinar na Galiza, onde o ensino para estrangeiros tem uma série de especificidades, sobretudo no que se refere ao (quase) pleno entendimento da língua e à tradição histórico-cultural compartilhada. Neste percurso é sugerida uma construção de repertório baseada na experiência empírica e moldada a partir da interdisciplinaridade, sobretudo com a presença da Literatura Comparada (com ênfase na Lusofonia).
LITERATURA EM PAUTA: AS PÁGINAS DE JORNAL DE ANTONIO CALLADO
Authors: Agazzi Giselle Larizzatti , Rodrigues Joana 
Published: December 2018

A escrita de Antonio Callado repórter dialoga com o que ficou conhecido como jornalismo literário, gênero híbrido, que desafia as expectativas do leitor de literatura e o leitor de reportagens. Com ampla atuação como jornalista, vindo a cobrir importantes eventos da história mundial, o intelectual carioca contribui de modo decisivo para a constituição do gênero no Brasil. Nas reportagens publicadas entre 1960 e 1970, o escritor encontra um estilo próprio, ao aprofundar o potencial simbólico da linguagem, compondo complexos panoramas em que a análise e a opinião crítica se combinam a um trabalho meticuloso com a arquitetura das palavras.