bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do novice and experienced rowers adopt different pacing strategies and do their physiological and metabolic responses show optimisation?
Authors: López-Sánchez G. F. , Smith L. , Díaz-Suárez A. , Towner A. , Gordon D. 
Published: April 2018

<p>El objetivo fue evaluar las estrategias de ritmo y las respuestas metabólicas y fisiológicas de remeros novatos y experimentados, en distancia de 2000m. La muestra estuvo compuesta por 7 remeros universitarios y de clubes, 5 de los cuales eran novatos (edad 22.4±2.6 años, altura 182.6±8.4 cm, peso 79.7±8.9 kg), y 2 experimentados (edad 23.0±4.2 años, altura 194.1±4.1 cm, peso 90.3±2.0 kg). Todos los participantes realizaron una prueba de 2000m en un ergómetro de remo, seguidos por 3 pruebas en orden aleatorio (500m, 1000m, 1500m) a la velocidad y tiempo de carrera establecidos según la primera prueba de 2000m. La última sesión fue un test de <sub>2max</sub>. Durante estas pruebas se realizó análisis de gases, hematología, frecuencia cardiaca, tiempos parciales, velocidad de carrera y distancias. La acumulación de lactato en sangre (BLa) en los remeros novatos se incrementó progresivamente y se estabilizó en los últimos 500m. Los remeros experimentados aumentaron gradualmente la acumulación de lactato, pero lo mantuvieron en el tercer cuarto (1000-1500m), lo que les permitió mayor acumulación en el cuarto final (1500-2000m). El volumen de consumo de oxígeno ( <sub>2</sub>) aumentó linealmente hasta los 500m finales en los remeros experimentados, mientras que en los remeros novatos fluctuó durante toda la prueba. Respecto al ritmo, los remeros novatos siguieron la estrategia “all-out” esperada, mientras que, inesperadamente, los remeros experimentados disminuyeron la velocidad progresivamente hasta el punto medio (1000m), en el que mantuvieron una velocidad de 5.10m<sup>.</sup>s<sup>-1</sup>. Estos resultados sugieren que a un determinado nivel fisiológico y metabólico, los remeros experimentados están más adaptados a las demandas de una regata de remo de 2000m. Sin embargo, parece que no siempre siguen una estrategia “J-Shaped”.</p>
Genetic bottleneck and founder effect signatures in a captive population of common bottlenose dolphins Tursiops truncatus (Montagu 1821) in Mexico
Authors: Améndola-Pimenta Monica , Camelo-Marrufo Miriam , Zamora-Briseño Jesús Alejandro , Hernández-Velázquez Ioreni Margarita , Zamora-Bustillos Roberto , Rodriguez Canul Rossanna 
Published: April 2018

Background. The captive cetacean industry is very profitable and popular worldwide, focusing mainly on leisure activities such as “Swim-with-dolphins” (SWD) programs. However, there is a concern for how captivity could affect the bottlenose dolphin Tursiops truncatus, which in nature is a highly social and widespread species. To date, there is little information regarding to the impact of restricted population size on their genetic structure and variability.
Methods. The aim of this study was to estimate the genetic diversity of a confined population of T. truncatus, composed of wild-born (n=25) from Cuba, Quintana Roo and Tabasco, and captive-born (n=24) dolphins in southern Mexico, using the hypervariable portion of the mitochondrial DNA and ten nuclear microsatellite markers: TexVet3, TexVet5, TexVet7, D18, D22, Ttr19, Tur4_80, Tur4_105, Tur4_141 and GATA098.
Results. Exclusive mtDNA haplotypes were found in at least one individual from each wild-born origin populations and in one captive-born individual; total mean haplotype and nucleotide diversities were 0.912 (±0.016) and 0.025 (±0.013) respectively. At microsatellite loci, low levels of genetic diversity were found with a mean number of alleles per locus of 4 (±2.36), and an average expected heterozygosity over all loci of 0.544 (±0.163). Measures of allelic richness and effective number of alleles were similar between captive-born and wild-born dolphins. No significant genetic structure was found with microsatellite markers, whereas the mtDNA data revealed a significant differentiation between wild-born organisms from Cuba and Quintana ROO.
Discussion. Data analysis suggests the occurrence of a recent genetic bottleneck in the confined population probably because of a strong founder effect, given that only a small number of dolphins with a limited fraction of the total species genetic variation were selected at random to start this captive population. The results herein provide the first genetic baseline information on a captive bottlenose dolphin population in Mexico.
<b>Variações sobre teatro e audiovisual</b><br />[Roberta Matsumoto]
Authors: Matsumoto Roberta 
Published: April 2018

<p class="p1">Resumo:<span class="Apple-converted-space"> </span></p><p class="p3">Nos últimos 30 anos, o diálogo entre o teatro e as tecnologias de produção de imagem tem se tornando cada vez mais intenso, sobretudo com o advento do sistema digital que vem possibilitado a miniaturização dos dispositivos e sua disseminação. Neste artigo, apontamos alguns caminhos de diálogo entre o teatro e o audiovisual no que diz respeito à presença de tais tecnologias como elemento de encenação do espetáculo teatral e à sua utilização como ferramentas que auxiliam o processo de criação e a pesquisa em teatro.<span class="Apple-converted-space"> </span></p><p class="p4"><span class="s1">P</span>alavras<span class="s1">-</span>chave<span class="s1">:<span class="Apple-converted-space"> </span></span>Teatro. Audiovisual. Cinema. Encenação teatral. Metodologia de pesquisa em artes cênicas.<span class="Apple-converted-space"> </span></p><p class="p4"><span class="Apple-converted-space"><br /></span></p><p><em>VARIATIONS ON THEATER AND AUDIO-VISUAL MATERIAL</em></p><p class="p4"><em>Abstract:<span class="Apple-converted-space"> </span></em></p><p class="p3"><em>During the last thirty years, the interactions between theater and imaging technologies has become increasingly intense. The advent of digital system technology allowed this process to develop even further due to shrinking and dissemination of such devices. In this paper, we highlight some forms of creating interaction between theater and audio-visual material. We focus on describing the use of such technologies as elements of the staging process and also its use as tools that contribute to the process of creating and researching theater.<span class="Apple-converted-space"> </span></em></p><p class="p4"><span class="s1"><em>K</em></span><em>eywords</em><span class="s1"><em>:<span class="Apple-converted-space"> </span></em></span><em>Theater. Audio-visual. Cinema. Theatrical performance. Methodological approaches to performing arts research.<span class="Apple-converted-space"> </span></em></p>
<b>Kinetic Dance: performance e jogo do corpo digital</b><br />
Authors: Araújo Marlus , Moraes Marcus 
Published: April 2018

<p class="p1">Resumo:<span class="Apple-converted-space"> </span></p><p class="p2">Relato do processo de pesquisa experimental do grupo Kinetic.Lab, do Rio de Janeiro, na área de dança e tecnologia. Descrição técnica e conceitual da montagem da <em>performance </em>“Kinetic Dance”, com algumas referências ao pensamento do filósofo Vilém Flusser e dos teóricos da multimídia, Roy Ascott e Steve Dixon.</p><p class="p3"><span class="s1">Palavras-chave:<span class="Apple-converted-space"> </span></span>Multimídia. Dança. Performance. Videoprojeção.</p><p> </p><p>KINETIC DANCE: PERFORMANCE AND GAME OF A DIGITAL BODY</p><p class="p1"><em>Abstract:</em></p><p class="p2"><em>Report of experimental research by Kinetic.Lab Group, from Rio de Janeiro, Brazil, about dance and technology. Technical and conceptual description of the performance “Kinetic Dance”, with some references about the work of the philosopher Vilém Flusser and the multimedia theorists, Roy Ascott and Steve Dixon.</em></p><p class="p3"><span class="s1"><em>Keywords:<span class="Apple-converted-space"> </span></em></span><em>Multimedia. Dance. Performance. Videoprojection.</em></p>
<b>A dança como interface: um exemplo de práticas criativas em dança com mediação tecnológica</b><br />
Authors: Cardoso Mab 
Published: April 2018

<p class="p1">Resumo:<span class="Apple-converted-space"> </span></p><p class="p2">Este artigo tem como ponto de partida investigar as práticas criativas no campo da dança com mediação tecnológica e suas imbricações com conceitos da <em>performance</em>. Consciente das potencialidades deste campo emergente e híbrido, este estudo é baseado na observação de algumas práticas artísticas e tem como objetivo refletir acerca do corpo como interface, bem como seus potenciais criativos no campo da arte e tecnologia.<span class="Apple-converted-space"> </span></p><p class="p3"><span class="s1">Palavras-chave:<span class="Apple-converted-space"> </span></span>Dança. Interface. Tecnologia. <em>Performance</em>. Mídia.</p><p class="p3"> </p><p class="p3">DANCE AS INTERFACE: AN EXAMPLE OF CREATIVE PRACTICES IN DANCE AND TECHNOLOGICAL MEDIATION</p><p class="p1"><em>Abstract:<span class="Apple-converted-space"> </span></em></p><p class="p2"><span class="s1"><em>The starting point of this article is the investigation of creative practices in the field of dance with technological mediation and its imbrications with the concepts of performance. Aware of its potencialities as a hybrid field, this study is based on the observation of some artistic practices. It aims to reflect on the body as an interface, as well its creative potencial in the field of art and technology.</em></span></p><p class="p3"><span class="s1"><em>Keywords:</em></span><em>Dance. Interface. Tecnology. Performance. Media.</em></p>
<b>Entrevista com Christian Mio Loclair</b><br />
Authors: Barretto Francisco 
Published: April 2018

<p class="p1">Resumo:</p><p class="p2">Essa entrevista busca compreender as conexões estabelecidas pelo dançarino, coreógrafo e engenheiro de computação CHRISTIAN MIO LOCLAIR entre essas áreas de conhecimento nas quais se especializou com distinção. Considerando duas características marcantes do entrevistado, a saber, ele é campeão de vários festivais de dança urbana e também um exímio programador, interessa saber como ele percebe esse entrelaçamento entre movimento e código no espaço da dança contemporânea, espaço ao qual encaminhou sua produção artística. A entrevista pretende compreender um pouco do processo criativo da artista, bem como suas próprias sensações como dançarino e programador. Diferente da grande maioria dos projetos nessa área, ele é autor e usuário do sistema interativo, ele cria o código computacional para interagir com seu próprio corpo buscando novas estéticas. Essa entrevista pretende falar desse corpo-híbrido da era digital.</p><p class="p3"><span class="s1">Palavras-chave:<span class="Apple-converted-space"> </span></span>Dança urbana. Arte mídia. Sistemas interativos. Processo criativo.</p><p class="p3"> </p><p>INTERVIEW WITH CHRISTIAN MIO LOCLAIR</p><p class="p1"><em>Abstract:</em></p><p class="p5"><em>This interview seeks to understand the connections established by the dancer, choreographer and computer engineer CHRISTIAN MIO LOCLAIR among those areas of knowledge in which he specializes with distinction. Considering two outstanding characteristics of the interviewer, namely, he is champion of several urban dance festivals and an excellent programmer, it is interesting to know how he perceives this entanglement between movement and code in the space of contemporary dance, space to which he directed his artistic production. The interview aims to understand a little of the creative process of the artist, as well as their own feelings as a dancer and programmer. Unlike most existing projects in this area, he is the author and the user of the interactive system, he creates the computational code to interact with his own body seeking new aesthetics. This interview intends to speak of this hybrid-body of the digital age.</em></p><p class="p3"><span class="s1"><em>Keywords:<span class="Apple-converted-space"> </span></em></span><em>Urban dance. Media arts. Interactivity systems. Creative process.</em></p>
<b>O corpo mediador: dança e mediação no museu</b><br />
Authors: Da Silva Aila Regina 
Published: April 2018

<p class="p1">Resumo:<span class="Apple-converted-space"> </span></p><p class="p2">De um simples piscar de olhos a um pulo, a dança traz ao ser humano novos meios de conectar-se consigo e com o espaço a sua volta. Este artigo é um estudo sobre as relações da mediação com dança em comparação aos processos do <em>site specific</em> e performance, como produtos indiretos da experiência mediativa. Recorte da pesquisa de mestrado <em>Proibido tocar, permitido dançar: dança e mediação no museu de arte contemporânea</em>, que submete um grupo heterogêneo de pessoas a vivências de dança e, posteriormente, ao diálogo sobre a obra de arte no Museu de Arte Contemporânea da Universidade de São Paulo.</p><p class="p3"><span class="s1">Palavras-chave:<span class="Apple-converted-space"> </span></span>Dança. Performance. <em>Site specific</em>. Mediação.<span class="Apple-converted-space"> </span></p><p class="p3"><span class="Apple-converted-space"><br /></span></p><p>MEDIATOR BODY: DANCE AND MEDIATION IN THE MUSEUM</p><p class="p1"><em>Abstract:<span class="Apple-converted-space"> </span></em></p><p class="p5"><em>From a simple blink of eyes to an action of jumping, the dance provides to the human being new connections with himself and with the space around him. This article is a study about the relation among the mediation with dance, ‘site specific’ process and performance as indirect products from the mediation experience. Part of the Masters’ project “Do not touch. Dance, though. Dance and mediation in the Contemporary Museum</em><span class="s2"><em>”, the project put a heterogeneous group into living mediations that combine dance improvisations as a way to talk about contemporary art.</em></span></p><p class="p6"><span class="s1"><em>Keywords:<span class="Apple-converted-space"> </span></em></span><em>Dance. Performance. Site specific. Mediation.</em></p>
Tofacitinib in Rheumatoid Arthritis: Lack of Early Change in Disease Activity and the Probability of Achieving Low Disease Activity at Month 6
Authors: van Vollenhoven Ronald F. , Lee Eun Bong , Fallon Lara , Zwillich Samuel H. , Wilkinson Bethanie , Chapman Douglass , DeMasi Ryan , Keystone Edward 
Published: April 2018

ObjectiveOptimal targeted treatment in rheumatoid arthritis requires early identification of failure to respond. This post hoc analysis explored the relationship between early disease activity changes and the achievement of low disease activity (LDA) and remission targets with tofacitinib.MethodsData were from 2 randomized, double‐blind, phase III studies. In the ORAL Start trial, methotrexate (MTX)–naive patients received tofacitinib 5 or 10 mg twice daily, or MTX, for 24 months. In the placebo‐controlled ORAL Standard trial, MTX inadequate responder patients received tofacitinib 5 or 10 mg twice daily or adalimumab 40 mg every 2 weeks, with MTX, for 12 months. Probabilities of achieving LDA (using a Clinical Disease Activity Index [CDAI] score ≤10 or the 4‐component Disease Activity Score in 28 joints using the erythrocyte sedimentation rate [DAS28‐ESR] ≤3.2) at months 6 and 12 were calculated, given failure to achieve threshold improvement from baseline (change in CDAI ≥6 or DAS28‐ESR ≥1.2) at month 1 or 3.ResultsIn ORAL Start, 7.2% and 5.4% of patients receiving tofacitinib 5 and 10 mg twice daily, respectively, failed to show improvement in the CDAI ≥6 at month 3; of those who failed, 3.8% and 28.6%, respectively, achieved month 6 CDAI‐defined LDA. In ORAL Standard, 18.8% and 17.5% of patients receiving tofacitinib 5 and 10 mg twice daily, respectively, failed to improve CDAI ≥6 at month 3; of those who failed, 0% and 2.9%, respectively, achieved month 6 CDAI‐defined LDA. Findings were similar when considering improvements at month 1 or DAS28‐ESR thresholds.ConclusionIn patients with an inadequate response to MTX, lack of response to tofacitinib after 1 or 3 months predicted a low probability of achieving LDA at month 6. Lack of an early response may be considered when deciding whether to continue treatment with tofacitinib.
Effects of Aerobic and Resistance Exercise in Older Adults With Rheumatoid Arthritis: A Randomized Controlled Trial
Authors: Lange Elvira , Kucharski Daniel , Svedlund Sara , Svensson Karin , Bertholds Gunhild , Gjertsson Inger , Mannerkorpi Kaisa 
Published: April 2018

ObjectiveTo evaluate the effect of a moderate‐to‐high–intensity, aerobic and resistance exercise with person‐centered guidance in older adults with rheumatoid arthritis (RA), through a randomized controlled multicenter trial.MethodsOlder adults (ages 65–75 years) with RA (n = 74) were randomized to either a 20‐week exercise intervention at a gym (n = 36) or to home‐based exercise of light intensity (n = 38). Assessments were performed at baseline, at 20 weeks, and at 12 months. The primary outcome was the difference in the Health Assessment Questionnaire disability index (HAQ DI) score, and the secondary outcomes were the differences in physical fitness assessed by a cardiopulmonary exercise test, an endurance test, the timed up and go test, the sit to stand test, and an isometric elbow flexion force measurement.ResultsNo significant differences between the groups were found for the primary outcome, HAQ DI score. Within the intervention group there was a significant improvement in the HAQ DI score when compared to baseline (P = 0.022). Aerobic capacity (P < 0.001) and 3 of 4 additional performance‐based tests of endurance and strength significantly improved (P < 0.05) in the intervention group when compared to the control group. In the intervention group, 71% of patients rated their health as much or very much improved compared to 24% of patients in the control group (P < 0.001). At the 12‐month follow‐up, there were no significant differences in change between the 2 groups on the HAQ DI score. A significant between‐group difference was found for change in an endurance test (P = 0.022).ConclusionAerobic and resistance exercise with person‐centered guidance improved physical fitness in terms of aerobic capacity, endurance, and strength in older adults with RA.
Hyaluronan‐Based Nanohydrogels for Targeting Intracellular S. Aureus in Human Keratinocytes
Authors: Montanari Elita , Oates Angela , Di Meo Chiara , Meade Josephine , Cerrone Rugiada , Francioso Antonio , Devine Deirdre , Coviello Tommasina , Mancini Patrizia , Mosca Luciana , Matricardi Pietro 
Published: April 2018

AbstractStaphylococcus aureus is one of the most significant human pathogens that is frequently isolated in a wide range of superficial and systemic infections. The ability of S. aureus to invade and survive within host cells such as keratinocytes and host immune cells has been increasingly recognized as a potential factor in persistent infections and treatment failures. The incorporation of antibiotics into hyaluronan‐cholesterol nanohydrogels represents a novel paradigm in the delivery of therapeutic agents against intracellular bacteria. The work presented herein shows that NHs quickly enter human keratinocytes and accumulate into lysosomes. When used for targeting intracellular S. aureus the antimicrobial activity of loaded levofloxacin is enhanced, possibly changing the antibiotic intracellular fate from cytosol to lysosome. Indeed, gentamicin, an antibiotic that predominantly accumulates in lysosomes, shows significant and equal antibacterial activity when entrapped into NHs. These results strongly suggest that lysosomal formulations may display preferential activity toward intracellular S. aureus, opening new avenues for the use of HA‐based NHs for treatment of such skin infections.
Metal‐Halide Perovskites for Gate Dielectrics in Field‐Effect Transistors and Photodetectors Enabled by PMMA Lift‐Off Process
Authors: Daus Alwin , Roldán‐Carmona Cristina , Domanski Konrad , Knobelspies Stefan , Cantarella Giuseppe , Vogt Christian , Grätzel Michael , Nazeeruddin Mohammad Khaja , Tröster Gerhard 
Published: April 2018

AbstractMetal‐halide perovskites have emerged as promising materials for optoelectronics applications, such as photovoltaics, light‐emitting diodes, and photodetectors due to their excellent photoconversion efficiencies. However, their instability in aqueous solutions and most organic solvents has complicated their micropatterning procedures, which are needed for dense device integration, for example, in displays or cameras. In this work, a lift‐off process based on poly(methyl methacrylate) and deep ultraviolet lithography on flexible plastic foils is presented. This technique comprises simultaneous patterning of the metal‐halide perovskite with a top electrode, which results in microscale vertical device architectures with high spatial resolution and alignment properties. Hence, thin‐film transistors (TFTs) with methyl‐ammonium lead iodide (MAPbI3) gate dielectrics are demonstrated for the first time. The giant dielectric constant of MAPbI3 (>1000) leads to excellent low‐voltage TFT switching capabilities with subthreshold swings ≈80 mV decade−1 over ≈5 orders of drain current magnitude. Furthermore, vertically stacked low‐power Au‐MAPbI3‐Au photodetectors with close‐to‐ideal linear response (R2 = 0.9997) are created. The mechanical stability down to a tensile radius of 6 mm is demonstrated for the TFTs and photodetectors, simultaneously realized on the same flexible plastic substrate. These results open the way for flexible low‐power integrated (opto‐)electronic systems based on metal‐halide perovskites.
Superior Energy Storage Performances of Polymer Nanocomposites via Modification of Filler/Polymer Interfaces
Authors: Zhang Xin , Li Bao‐Wen , Dong Lijie , Liu Hanxin , Chen Wen , Shen Yang , Nan Ce‐Wen 
Published: April 2018

AbstractDielectric polymer nanocomposites by integration of high‐E
b polymer matrix and high‐D(εr) ceramic fillers have shown great potential for dielectric and energy storage applications in modern electronic and electrical systems. Interface between ceramic fillers and polymer matrix is considered as a predominant factor to determine the dielectric performances of the nanocomposites. This review analyzes the influence of the interface on dielectric responses and breakdown strength in the nanocomposites, and discusses the viability of current interface engineering strategies in improving their energy storage capabilities. Two scopes of current interface modification approaches are focused from both structural and functional considerations in the dielectric ceramics/polymer nanocomposites: first, the organic/inorganic interface compatibility can be modified to generate homogeneous dispersion of ceramic nanoparticles in polymer matrix, which is the premise of fully realizing the synergistic combination of advantages of polymer and ceramic fillers; second, regulated local electrical and dielectric behaviors in interface region enable the enhancement of dielectric properties (both high dielectric constant and high breakdown strength) in resultant nanocomposites. In the last part, some present challenges and future perspectives are proposed to utilize the interface strategy for developing high energy density ceramics/polymer nanocomposites for dielectric and energy storage applications.