bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Gender on Postoperative Complications after Revision Total Knee Arthroplasty
Authors: Gu Alex , Wei Chapman , Bernstein Simone A. , Nguyen Nam Tran T. , Sobrio Shane A. , Liu Jiabin , Sculco Peter K. 
Published: February 2019

AbstractKnee osteoarthritis is a common form of arthritis, often treated by total knee arthroplasty (TKA). Complications can arise after TKAs, which may necessitate revision TKAs and further treatments. However, there remains a paucity of literature regarding influence of gender on postoperative complication rates after revision TKA. A retrospective cohort study was conducted using the American College of Surgeons National Surgical Quality Improvement Program database. Patients who received revision TKAs between 2007 and 2014 were identified and recorded as male or female. Univariate and multivariate analysis was used to evaluate the incidence of multiple adverse events within 30 days of revision TKA. This study included 9,914 patients who underwent revision TKA (females = 5,728 [57.8%]; males = 4 186 [42.2%]). Male patients were shown to be at greater risk for developing 7 of 17 complications compared with female patients, and female patients were shown to be at greater risk for urinary tract infection (UTI) development. Multivariate analysis showed males as an independent risk factor for four complications and females as an independent risk factor for UTI development. Male patients were more likely to develop more complications postoperatively than female patients. Although the possibility of developing complications is relatively low, orthopaedic surgeons should be aware of increased postoperative complication rates when counseling patients who undergo revision TKA.
Total Knee Arthroplasty for Fixed Valgus Deformity Correction Using a Modified Lateral Parapatellar Approach
Authors: Li Hu , Ponzio Danielle Y. , Ong Alvin , Wei Wei , Wang Baicheng , Li Zhichang , Zhou Diange 
Published: February 2019

AbstractTotal knee arthroplasty (TKA) for patients with valgus deformity (> 10 degrees) is technically challenging and has produced variable clinical results in terms of deformity correction, instability, and overall outcomes. The lateral parapatellar approach (LPA) is an alternative to the traditional medial parapatellar approach with potential advantages of direct access for release of tight lateral ligamentous structures with preservation of the medial structures, optimized patellar tracking, preserved medial blood supply to the patella, and less use of constrained implants. We present a case series of a single institution's experience with use of a modified LPA using a Z-capsuloplasty for 35 primary TKA cases in 30 patients with osteoarthritis and Ranawat's type-II fixed valgus deformity with attenuation of medial soft tissues. The mean age of patients was 64.8 years (range: 42–78 years). Follow-up duration was a mean of 47.3 months (range: 3–130 months). The patients were assessed pre- and postoperatively using radiographic measurement of the anatomic femorotibial angle (FTA) and clinical measurement of range of motion (ROM) and the Chinese knee society score (KSS). Complications and reoperations were recorded. The mean coronal alignment was corrected from 20.4 degrees of valgus (range: 11.3–42 degrees) preoperatively to 7.0 degrees of valgus (range: 3.6–15.1 degrees) postoperatively. One case required use of a constrained condylar design implant. At a mean of 47.3 months, the mean Knee Society objective and functional scores improved to 91.8 ± 6.6 and 84.3 ± 18.2 points, respectively. Mean ROM was 94.9 degrees preoperatively and 105.7 degrees postoperatively. Three cases (8.6%) had postoperative complications, including transient common peroneal nerve palsy, hematoma, and deep infection. One patient underwent two-stage revision for infection. There were no cases of late instability. The modified LPA using a Z-capsuloplasty is a reproducible and effective surgical technique for performing TKA in the setting of osteoarthritis and severe valgus deformity.
Pericardial fluids or Cardiopulmonary Bypass—Is There a Major Culprit for Changes in Coagulation and Inflammation?
Authors: Gorki Hagen , Nakamura Julia , Kunert Andreas , Hoenicka Markus , Liebold Andreas 
Published: February 2019

Abstract
Background From the results of a previous study, it remained to be investigated if a perioperative rise of few tested coagulation and inflammation markers is caused by conventional cardiopulmonary bypass (CPB) itself or rather by direct recirculation of pericardial fluids.
Methods Forty-eight patients operated on with conventional CPB for myocardial revascularization were randomized either for direct recirculation of pericardial suction fluids or for cell saving (CS).
Results Thrombin–antithrombin complexes showed lower values intraoperatively in the CS group (p < 0.0001), and D-dimers tended to remain lower at intensive care unit arrival (p = 0.095). Tests of inflammation markers were less meaningful.
Conclusion Direct recirculation of pericardial fluids rather than conventional CPB itself causes major intraoperative changes of some coagulation markers. Pericardial blood loss with direct recirculation should be kept to a minimum to avoid unnecessary activation of coagulation. Inflammation markers need further investigations.
Radiation Exposure during Percutaneous Endoscopic Lumbar Discectomy: Interlaminar versus Transforaminal
Authors: Amato Marcelo , Aprile Bruno , de Oliveira Cezar 
Published: February 2019

Objective Percutaneous endoscopic lumbar discectomy (PELD) relies heavily on fluoroscopy guidance; therefore, medical staff exposure to radiation has become an important issue. The purpose of this study was to determine the radiation dose and the amount of time to which the surgeons are exposed during PELD and to compare both parameters in the transforaminal (TF) and interlaminar (IL) approaches. Although they are considerably different, they may be wrongly considered together.
Methods A retrospective evaluation of the last 20 PELD performed by the authors is presented. Patients were distributed in 2 groups. Six (1F, 5M) patients were submitted to IL-PELD and 14 (6F, 8M) to TF-PELD. Fluoroscopy reports were obtained from patients' records, all performed with the same C-Arm device and software mode. Groups were compared using unpaired t-test.
Results The IL group showed an average radiation exposure of 8.37 ± 4.21 mGy and duration of 11.1 ± 5.45 seconds, while the TF group showed an average radiation exposure of 28.92 ± 7.56 mGy and duration of 42 ± 16.64 seconds. The p-value for radiation was 0.0000036, and for time it was 0.00027.
Conclusions Interlaminar PELD requires a lower radiation dose and a shorter amount of exposure than TF-PELD. Studies that concern radiation required for minimally-invasive spine surgeries should consider the PELD approaches separately.
Neutrophil Extracellular Traps Enhance Staphylococcus Aureus Vegetation Formation through Interaction with Platelets in Infective Endocarditis
Authors: Hsu Chih-Chieh , Hsu Ron-Bin , Ohniwa Ryosuke , Chen Jeng-Wei , Yuan Chang-Tsu , Chia Jean-San , Jung Chiau-Jing 
Published: February 2019

AbstractThe mechanisms or host factors involved in septic thrombus or vegetation formation in Staphylococcus aureus-induced infective endocarditis (IE) are unclear. Using an experimental endocarditis rat model, here we demonstrated that S. aureus HG001-induced vegetation was composed of bacterial floes encased in aggregated platelets and surrounded by neutrophil extracellular traps (NETs). In vitro data demonstrated that platelets contribute to both biofilm and NET formation. Prophylactic administration of DNase I significantly reduced the size of vegetation induced by methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) strains, even though MRSA and MSSA isolates express different biofilm phenotypes and NET-induction abilities in the presence of platelets. Moreover, delivery of both DNase I and daptomycin prophylactically and therapeutically produced synergistic effects by reducing vegetation size and bacterial numbers on damaged valve tissues in MRSA-induced IE. Together, these data suggest that NETs contribute to vegetation formation in S. aureus endocarditis and DNase I has the potential to control S. aureus-induced IE in the clinic.
12 Acridinium Dyes and Quinones in Photocatalysis
Authors: Brasholz M. 
Published: February 2019

AbstractAcridinium dyes and quinones are two classes of powerful organic photooxidants. This chapter reviews the most important types of photocatalytic transformations mediated by these dyes, including photooxygenations, radical conjugate additions and cyclizations, radical cation cycloadditions, and oxidative C–H functionalizations.
16 Photocatalytic Cycloadditions
Authors: Amador A. G. , Scholz S. O. , Skubi K. L. , Yoon T. P. 
Published: February 2019

AbstractPhotochemical cycloadditions are powerful tools for the rapid construction of molecular and stereochemical complexity. Recent advances in visible-light photocatalysis have provided novel methods involving the generation of radical ion, neutral radical, and triplet excited-state intermediates that can participate in a variety of cycloaddition processes. This chapter highlights recent methods in this area for the synthesis of three-, four-, five-, and six-membered-ring systems.
19 Heterogeneous Photocatalysis in Organic Synthesis
Authors: Albero J. , García H. 
Published: February 2019

AbstractIn recent years, heterogeneous photocatalysis has emerged as a very appealing approach, not only for the degradation of pollutants, but also for the synthesis of chemicals. Although the main use of heterogeneous photocatalysis so far has been the mineralization and complete degradation of organic compounds, interest in the application of heterogeneous (photo)catalysts in organic synthesis is growing due to their potential application in the fabrication of renewable fuels as well as in the preparation of compounds and intermediates especially valuable to the chemical industry, such as pharmaceuticals or polymers. The synthesis of organic molecules assisted by heterogeneous photocatalysts has been dominated by the use of inorganic metal oxide semiconductors, especially titanium(IV) oxide; the use of other semiconductor materials, such as inorganic chalcogenides, carbon-based semiconductors, or metal–organic frameworks has been less explored. In this chapter we show that, in spite of the potential and the large number of heterogeneous photocatalysts already studied, the state of the art of heterogeneous photocatalysis in organic synthesis is still unsatisfactory and much below expectation, particularly in reactions other than oxidation and reduction, such as cross couplings, oxidative decarboxylations, and cycloadditions.
Physicochemical measurements of Japonica rice cultivars in Heilongjiang Province
Authors: Nakamura Sumiko , Li Hui , Dai Chang-Jun , Zhang Rui-Ying , Kawano Motonobu , Ohtsubo Ken’Ichi 
Published: February 2019

ABSTRACT
We here characterized 27 japonica rice cultivars grown in Heilongjiang province and evaluated the relationship among their iodine absorption curve, physical properties, and ratio of 13 kDa prolamin. We developed the novel estimation formulae for ratio of 13 kDa prolamin and overall hardness (H2) with the use of Aλmax and λmax.
Atypical variants of posterior canal benign paroxysmal positional vertigo after canalith repositioning
Authors: Wagner Andrew R. 
Published: February 2019

Background and purpose:
Unsuccessful repositioning of posterior canal benign paroxysmal positional vertigo (PC-BPPV) can result in inadvertent aggregation of otoconia in atypical areas of the PC. A collection of otoconia within the non-ampullary segment of the PC can provoke a downbeating and torsional positional nystagmus creating diagnostic uncertainty. Further complicating the clinical picture, otoconia may concurrently become displaced in areas adjacent to the utricle, such as the utricular side of the PC ampulla. Current evidence regarding the treatment of atypical PC-BPPV is limited, and the ideal treatment method remains in question.

Case description:
This case report describes the management of an individual presenting with atypical downbeating and torsional positional nystagmus of PC origin. The simultaneous presence of reversed nystagmus when positioned in supine with the head flexed 30 degrees, further complicated the differential diagnosis.

Intervention:
This individual was treated with the demi-semont (DS) maneuver to treat suspected right-sided apogeotropic posterior canal BPPV (APC-BPPV) with concurrent utricular side cupulolithiasis of the posterior canal (UCPC-BPPV).

Outcome and discussion:
When reassessed the day after treatment the patient’s positional nystagmus and vertigo were resolved, indicating successful treatment of suspected APC-BPPV with concurrent UCPC-BPPV. The patient, in this case, responded to the DS maneuver, however, the current evidence regarding of semicircular canal fluid mechanics supports minimizing the inertial elements of canalith repositioning maneuvers, while extending the duration of the rest intervals during the repositioning maneuver. In patients that present with positional downbeating nystagmus, without signs of central pathology, we suggest considering APC-BPPV as a potential diagnosis. In addition, we suggest that excitation of the PC in the supine head flexed (SHF) position without similar findings in the DH position may represent aggregation of otoconia on the posterior side the cupula within the PC ampulla.
Cancer-related proteins in serum are altered in workers occupationally exposed to polycyclic aromatic hydrocarbons: a cross-sectional study
Authors: Alhamdow Ayman , Tinnerberg Håkan , Lindh Christian , Albin Maria , Broberg Karin 
Published: February 2019

AbstractExposure to some polycyclic aromatic hydrocarbons (PAH) increases the risk of cancer and is common particularly for workers in occupations such as chimney sweeping. In exposed workers, screening of early cancer-related markers provides important information to identify individuals at risk. Here, we aimed to elucidate the associations between PAH exposure and serum levels of cancer-related proteins in 118 chimney sweeps and 126 occupationally unexposed controls, all non-smoking males from Sweden. Monoydroxylated metabolites of pyrene, phenanthrene, benzo[a]pyrene and benzo[a]anthracene were measured in urine using liquid chromatography coupled to tandem mass spectrometry and 90 cancer-related proteins were measured in serum using a proximity extension assay. Linear regression analysis adjusted for age and body mass index, and false discovery rate (FDR) identified 17 serum proteins that were differentially expressed (16 upregulated and 1 downregulated) in chimney sweeps compared with controls (FDR < 0.05). Concentrations of the peptidase kallikrein 13 (KLK13) showed significant positive associations with urinary concentrations of the PAH metabolites 3-hydroxybenzo[a]pyrene (3-OH-BaP) [B, 95% confidence interval (CI): 0.042, 0.008–0.076] and 3-hydroxybenzo[a]anthracene (3-OH-BaA) (B, 95% CI: 0.068, 0.002–0.134). Moreover, dose–response relationships were observed between KLK13 and 3-OH-BaP (trend test P = 0.027) and 3-OH-BaA (P = 0.035). Pathway and gene ontology analyses showed that cell movement, cell adhesion and cell migration were the predominant molecular functions associated with the top differentially expressed proteins. In conclusion, we found a number of putative cancer-related proteins differentially expressed in workers exposed to PAH. This warrants effective measure to reduce PAH exposure among workers as well as further investigation to confirm these findings.
A Neonicotinoid Affects the Mating Behavior of Spalangia endius (Hymenoptera: Pteromalidae), a Biological Control Agent of Filth Flies
Authors: Kremer Aspen N , King Bethia H 
Published: February 2019

AbstractSpalangia endius Walker is a parasitoid wasp that is commercially available as a biological control agent for filth fly pests in livestock-rearing operations. Imidacloprid is often used to control these flies. The present study examined the sublethal effect of field-realistic concentrations of imidacloprid on mating behavior, offspring sex ratios, and male preference for virgin females. After exposure to imidacloprid, S. endius females that survived were less likely to mate than control females, which will result in male-biased sex ratios because only mated females can produce daughters. Males did not avoid exposed females, but exposed females were almost always unreceptive. Males that survived exposure to imidacloprid exhibited reduced mating competitiveness against unexposed males. However, if an exposed male mated, his mate’s sex ratio and ability to control flies was unaffected. Exposed males were also still able to discriminate against mated, and thus usually unreceptive, females. Together with previous studies, these results suggest that not only does imidacloprid reduce the ability of S. endius females to survive and parasitize hosts, but when an exposed female does survive and parasitize hosts, she is likely to produce just sons, because of her lack of receptivity. More-male-biased populations of S. endius will decrease their efficacy for fly control. Thus, the use of imidacloprid along with this parasitoid may be financially inefficient for pest management.
Using graphic text-messaging to promote smoking cessation among first-generation Chinese and Korean male immigrants
Authors: Zhao Xiaoquan , Peterson Emily B , Oh Kyeung Mi , Cai Xiaomei 
Published: February 2019

Abstract
First-generation Chinese and Korean male immigrants in the United States are at high risk for tobacco use. This study pilot-tested a graphic, native-language text-messaging intervention to promote smoking cessation among these groups. First-generation Chinese and Korean male immigrant smokers (N = 71) were recruited from the Washington DC area. Participants were randomly assigned to one of four conditions based on a between-subjects 2 (graphic plus text or text-only messages) ï¿½ 2 (quitline information or quitting tips) design. The text-messaging intervention included 30 text messages in total and lasted one month. Participants completed an expired air carbon monoxide (CO) assessment and self-reported measures at both baseline and follow-up. Results show that, from baseline to follow-up, participants’ expired air CO levels decreased significantly (P = 0.001). Attitude toward quitting also became more positive (P = 0.028). Compared with text-only messages, graphic text messages produced greater positive changes in quitting attitudes (P = 0.039) and elicited greater fear response (P = 0.005). Compared with quitting tip messages, quitline information resulted in greater regret (P = 0.016) and fear (P = 0.051). These findings suggest that graphic text-messaging can be an effective method to promote smoking cessation among first-generation Chinese and Korean male immigrants.
A Comparison of sun, ovate, fs8.1 and Auxin Application on Tomato Fruit Shape and Gene Expression
Authors: Wang Yanping , Clevenger Josh P , Illa-Berenguer Eudald , Meulia Tea , van der Knaap Esther , Sun Liang 
Published: February 2019

AbstractElongated tomato fruit shape is the result of the action of the fruit shape genes possibly in coordination with the phytohormone auxin. To investigate the possible link between auxin and the fruit shape genes, a series of auxin (2,4-D) treatments were performed on the wild-type and the fruit shape near-isogenic lines (NILs) in Solanum pimpinellifolium accession LA1589 background. Morphological and histological analyses indicated that auxin application approximately 3 weeks before anthesis led to elongated pear-shaped ovaries and fruits, which was mainly attributed to the increase of ovary/fruit proximal end caused by the increase of both cell number and cell size. Fruit shape changes caused by SUN, OVATE and fs8.1 were primarily due to the alterations of cell number along different growth axes. Particularly, SUN caused elongation by extending cell number along the entire proximal-distal axis, whereas OVATE caused fruit elongation in the proximal area, which was most similar to the effect of auxin on ovary shape. Expression analysis of flower buds at different stages in fruit shape NILs indicated that SUN had a stronger impact on the transcriptome than OVATE and fs8.1. The sun NIL differentially expressed genes were enriched in several biological processes, such as lipid metabolism, ion transmembrane and actin cytoskeleton organization. Additionally, SUN also shifted the expression of the auxin-related genes, including those involved in auxin biosynthesis, homeostasis, signal transduction and polar transport, indicating that SUN may regulate ovary/fruit shape through modifying the expression of auxin-related genes very early during the formation of the ovary in the developing flower.
Widespread Pressure Pain Hypersensitivity, Health History, and Trigger Points in Patients with Chronic Neck Pain: A Preliminary Study
Authors: Castaldo Matteo , Catena Antonella , Fernández-de-las-Peñas César , Arendt-Nielsen Lars 
Published: February 2019

AbstractBackgroundPain sensitivity in chronic neck pain patients may be influenced by health conditions related to higher levels of widespread pressure pain hypersensitivity (sensitization). Trigger points have also been reported to play a role in the sensitization process.ObjectivesTo investigate the association between pressure pain thresholds, trigger points, and health conditions in patients with chronic neck pain.DesignOriginal research, preliminary study.SettingA private clinic.SubjectsThirty-four chronic mechanical neck pain patients and 34 chronic whiplash-associated neck pain patients, giving a final sample of 68 chronic neck pain patients.MethodsPatients underwent an assessment of pressure pain thresholds over the upper trapezius, extensor carpi radialis longus, and tibialis anterior muscles and were screened for the presence of trigger points in the upper trapezius muscle. Further, information about health history conditions was obtained and collected in a form.ResultsSignificantly negative correlations between all pressure pain thresholds and duration of health history conditions were found (all P &lt; 0.02). Significantly lower pressure pain thresholds (all P &lt; 0.01) were found in patients with active trigger points as compared with those with latent trigger points.ConclusionWidespread pressure pain hypersensitivity was associated with duration of health history conditions, suggesting that long-lasting health complaints may act as a triggering/perpetuating factor, driving sensitization in individuals with chronic neck pain. Active trigger points may be associated with higher widespread pressure hypersensitivity.