bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Sodium Tripolyphosphate on Oral Commensal and Pathogenic Bacteria
Authors: MOON JI-HOI , NOH MI HEE , JANG EUN-YOUNG , YANG SEOK BIN , KANG SANG WOOK , KWACK KYU HWAN , RYU JAE-IN , LEE JIN-YONG 
Published: June 2019

Abstract
Polyphosphate (polyP) is a food additive with antimicrobial activity. Here we evaluated the effects of sodium tripolyphosphate (polyP3, Na5P3O10) on four major oral bacterial species, in both single- and mixed-culture. PolyP3 inhibited three opportunistic pathogenic species: Fusobacterium nucleatum, Prevotella intermedia, and Porphyromonas gingivalis. On the contrary, a commensal bacterium Streptococcus gordonii was relatively less susceptible to polyP3 than the pathogens. When all bacterial species were co-cultured, polyP3 (≥ 0.09%) significantly reduced their total growth and biofilm formation, among which the three pathogenic bacteria were selectively inhibited. Collectively, polyP3 may be an alternative antibacterial agent to control oral pathogenic bacteria.
The Joint Effect of pH Gradient and Glucose Feeding on the Growth Kinetics of Lactococcus lactis CECT 539 in Glucose-Limited Fed-Batch Cultures
Authors: MALVIDO MÓNICA COSTAS , GONZÁLEZ ELISA ALONSO , BENDAÑA JÁCOME RICARDO J. , GUERRA NELSON PÉREZ 
Published: June 2019

Abstract
Two glucose-limited realkalized fed-batch cultures of Lactococcus lactis CECT 539 were carried out in a diluted whey medium (DW) using two different feeding media. The cultures were fed a mixture of a 400 g/l concentrated lactose and a concentrated mussel processing waste (CMPW, 101.72 g glucose/l) medium (fermentation I) or a CMPW medium supplemented with glucose and KH2PO4 up to concentrations of 400 g glucose/l and 3.21 g total phosphorus/l, respectively (fermentation II). For an accurate description and a better understanding of the kinetics of both cultures, the growth and product formation by L. lactis CECT 539 were both modelled, for the first time, as a function of the amounts of glucose (G) added and the pH gradient (VpH) generated in every realkalization and feeding cycle, by using an empirical polynomial model. With this modeling procedure, the kinetics of biomass, viable cell counts, nisin, lactic acid, acetic acid and butane-2,3-diol production in both cultures were successfully described (R
2 values > 0.970) and interpreted for the first time. In addition, the optimum VpH and G values for each product were accurately calculated in the two realkalized fed-batch cultures. This approach appears to be useful for designing feeding strategies to enhance the productions of biomass, bacteriocin, and metabolites by the nisin-producing strain in wastes from the food industry.
Predicative possession in the Novgorod Birch Bark documents in the Ural-Altaic context
Authors: Yurayong Chingduang 
Published: June 2019

This paper discusses predicative possessive constructions in the East Slavic languages, with a particular focus on the Old Novgorod Slavic dialect, in connection to the neighbouring Ural-Altaic languages. An areal-typological investigation shows that the East Slavic languages prefer the use of a locational possessive (mihi est), while the rest of Slavic and Europe’s Indo-European languages primarily use a have-possessive (habeo). Serving as primary data for this study, the dialect written in the Novgorod Birch Bark documents confirms a preference of the locational possessive over the have -possessive. The current study also evaluates three hypotheses on the origin of the East Slavic locational possessive, proposed in earlier studies: 1) a Uralic substrate, 2) a Slavic archaism and 3) a Northern Eurasian areal pattern. Given the typological survey as well as the empirical and historical comparative investigation, the locational possessive can be considered a preferred areal pattern across Northern Eurasia. Being a part of the macro contact zone of Northern Eurasia, the choice of locational possessive in the East Slavic languages is reinforced by the areal diffusion, especially from the close neighbouring languages, Uralic and Turkic.
Implikasi UUSPN Terhadap Pendidikan Islam
Authors: Abdurahman Abdurahman 
Published: June 2019

Manusia membutuhkan pendidikan dalam kehidupannya. Pendidikan merupakan usaha agar manusia dapat mengembangkan potensi dirinya melalui peoses pembelajaran dan/atau cara lain yang dikenal dan diakui oleh masyarakat. Pendidikan merupakan suatu hal yang sangat esensial dalam proses pemanusiaan dalam masyarakat yang berbudaya. Dalam era globalisasi dewasa ini terjadi perubahan yang dahsyat dalam kehidupan masyarakat. Kota tidak dapat menghindarkan diri dari tsunami globalisasi yang telah memasuki setiap jengkal kehidupan manusia modern. Di dalam era globalisasi ini terjadi loncatan-loncatan atau transformasi nilai-nilai kehidupan dan oleh sebab itu juga terjadi perubahan dalam proses pemanusiaan atau pendidikan
FAKTOR-FAKTOR YANG MENENTUKAN AUDIT DELAY
Authors: Surbakti Lidya Primta , Mashuri Ayunita Ajengtiyas Saputri 
Published: June 2019

This study is performed to examine the effect of Auditor’s Opinion, Solvency Size CPA Firm and profitability toward the probability to Audit Report Lag in Consumer Goods Industry in Indonesian Stock Exchange over period 2010-2012. The population of this research is 35 Consumer Goods Industry companies listed on the Indonesia Stock Exchange over period 2010-2012. The data is obtained based on corporate finance reporting that at publication. It is gained sample amount of 28 ompanies from 35 companies those are classified in Consumer Goods Industry in Indonesian Stock Exchange. The analysis technique used here is multiple linear regression and hypothesis test using t-statistic and F-statistic with level of significance 5%. This research results that uditor’s Opinion , Size CPA Firm, Solvency and Gain-Loss are not ignificant effect to Audit Report Lag. We suggest for investors in ndonesian Stock Exchange that paying attention others factor that egards Audit Report Lag because with those information theycan make the best decision for their investment..
PENGARUH KOMITMEN PROFESIONAL, LOCUS OF CONTROL, KESERIUSAN PELANGGARAN DAN SUKU BANGSA TERHADAP INTENSI WHISTLEBLOWING (Studi Empiris pada Pemerintahan Daerah DKI Jakarta)
Authors: Ridho Muhammad Sidqi , Rini Rini 
Published: June 2019

The purpose of this study was to examine the influence of professional commitment,locus of control, seriousness of wrongdoing and ethnic group on whistleblowingintentions. The respondents in this research is financial staff in working units of local government (SKPD) DKI Jakarta. The sample in this research were 39 financial staff in 7 working unit of local government (SKPD) DKI Jakarta. The method of determining the sample uses convenience sampling method. Methods of analysis to test the hypothesis is multiple regression analysis. The results showed that the seriousness of wrongdoing affect the whistleblowing intentions. However, professional commitment, locus of control and ethnic group have no effect on whistleblowing intentions.
PENGARUH DEWAN KOMISARIS, LEVERAGE, DAN STRUKTUR KEPEMILIKAN TERHADAP PENGUNGKAPAN ENTERPRISE RISK MANAGEMENT (ERM)
Authors: Cecasmi Jetmi Ade , Samin Samin 
Published: June 2019

The purpose of this study was to examine the influence of Board of Commissioner, Leverage, and Ownership Structure on the Enterprise Risk Management disclosure of banking firm listed in Indonesian Stock Exchange for the period from 2013 to 2015. Sampling technique using purposive sampling (purposive sampling method). The sampel used in this study is a banking company that meets the criteriaas set out in this study to obtain 21 banking. The data obtained derived from the annualreport and financial report of the banks publishe. The analysis technique used in this research is multiple linear regression to test the classical assumption first. The result showed that the Board of Commissioner have a significant influence on the Enterprise Risk Management Disclosure. Leverageand Ownership Structure is not significantly effects on Enterprise Risk Management Disclosure.
Survival analysis of elderly and senile patients with colon cancer of II–III stages
Authors: Kolesnik A. P. , Kolesnіk I. P. , Kechedzhyiev V. V. 
Published: June 2019

Introduction surgical treatment of elderly and senile cancer patients is becoming more common, due to the growing number of aging population. Optimization of surgical treatment of elderly patients remains an actual problem due to a significant number of comorbidities and a decrease in the functional reserves of the organism.
Purpose of the study. Analysis of the survival and determination of risk factors affecting the life expectancy of elderly patients with II–III stages of colon cancer.
Materials and methods. The analysis of case histories of 40 elderly and senile patients with II–III stages of the colon cancer, operated in the Zaporizhzhia Regional Clinical Oncology Dispensary in 2016.
Results and discussion. When analyzing the survival rate, it was noted that the overall 2-year survival rate was 80%. The analysis of survival depending on the stage showed that the total 2-year survival in patients with II stage of disease was 91,3%, and among patients with III stage it was 64,7% (p < 0,05). The overall 2-year survival for men was 68,2%, while for women it was 94,4% (p < 0,05). In patients with tumor localization in the right half of the large intestine, overall survival rates were lower compared with patients with tumor localization in the left half (62,5% and 91,7%, respectively, p < 0.05). Indicators of total 2-year survival in patients with I, II, III degree of blood loss were respectively 94,4%, 83,3%, 50% (p < 0,05).
The stage of the disease, tumor localization, sex, the degree of intraoperative blood loss, leukocytosis significantly correlate with the overall survival rates in elderly and senile patients with II–III stages of colon cancer(p < 0,05). Further study and search for new prognostic factors of surgical risk in elderly and senile patients with colorectal cancer are needed.
The ocular cardiac reflex effect study on cardiac hemodynamic parameters in healthy young mans
Authors: Palamarchuk A. I. 
Published: June 2019

Purpose of the study. Investigate changes of cardiac hemodynamic parameters caused by ocular cardiac reflex triggering in healthy men’s in youthful age.
Material and methods. 120 healthy male volunteers in youthful age were examined. The mean age was (19,2 ± 0,93 years). For ocularcardiac reflex (OCR) triggering we used a patented model «Device for dosed compression effects on the eyeballs» and «The method of ocular cardiac reflex triggering». On the basis of the obtained parameters of systolic (SBP) and diastolic (DBP) blood pressure, by arithmetic operations, pulse pressure (PP) and average flow pressure (AFP) and integrative parameters of cardiohemodynamics (CHD) – systolic blood volume (SBV), minute blood flow volume (MBFV), volumetric blood flow rate (V), total peripheral resistance (TPR) were determined.
Results. Three main types of cardiovascular system response on OCR triggering were identified. The first type – hypertensive (n = 30 (25%) of the total number of examined subjects) was characterized by a significant (p < 0,05) increase in heart rate, SBP, DBP, PP, AFP and other integrative parameters of CHD. The second, hypotonic type of the response (62 subjects; 51,7%) was characterized by a significant (p < 0,05) decrease in SBP, DBP, PP, AFP. Patients with third, dystonic type, of response (n = 28 (23,3%) of the total number examined subjects) showed significant bilateral changes of blood pressure parameters in a nonlinear dependence of compression power on the eyeballs. Determination CHD parameters directly after and 3 and 5 minutes after decompression of the air in the compression device we enabled to determine the subtype of the mobility of the nervous centers as a feature that complements the basic type. The subtype of normal mobility was revealed in 63,3% (n = 19) of subjects with the main hypertensive type of response, 69,3% (n = 43) of subjects with the main hypotonic and 60,7 % (n = 17) with the main dystonic type of response of the cardiovascular system. The inert subtype in the mobility of the cardiovascular system were identified in 36,7% (n = 11) individuals with hypertension is the main type of response, at 30,7% (n = 19) of individuals with primary hypotonic type of response and 39,3 % (n = 11) – distancing. The obtained typological changes in blood pressure parameters caused by OCR triggering allowed to reveal predisposition to hypertension, hypotension, dystonia and to predict the development of hypertension in patients with hypertensive type of response usin appropriate primary prevention changes in life style. The highest risk of hypertension development may be in persons with hypertensive inert type of reaction of the system of regulation of blood pressure on OCR triggering. Further studies are being conducted to confirm this assumption.
Mechanical bridge to heart transplantation
Authors: Nikonenko A. S. , Tanskyi V. G. 
Published: June 2019

Purpose of the study. The purpose of the work is to assess the effectiveness of using mechanical support for blood circulation in potential cardiac recipients who need urgent transplantation.
Material and methods. The study included 47 patients and divided into two groups. The first group included 8 potential cardiac recipients, who had established mechanical support for the BiVAD blood flow. The second group included 39 potential cardiac recipients, who had LVAD's mechanical support for the circulatory system. The main disease that led to the development of terminal congestive heart failure was dilated cardiomyopathy. The INTERMACS scale was used to assess the patient's status. A Scale for the Classification of Patients with Progressive Heart Failure. We used the UNOS scale to assess the status of the patient who needed orthotopic cardiac transplantation. The algorithm of the Thoracic Committee of a single size distribution of organs for determining the urgent implementation of cardiac transplantation.
Results and discussion. Biventricular support is necessary for patients with high central venous pressure, increased pulmonary vascular resistance or with malignant arrhythmias, resistant to drug therapy. For the purpose of the final therapy and biventricular support, the system of choice can be a fully artificial heart.
Conclusions. Indications for biventricular circulation support are pronounced hemodynamic manifestations of impaired pumping function of the right and left ventricles of the transplanted heart. Systems DK (VAD) is the most effective «bridge to transplantation». It is important to choose the device for the patient, not the patient for the device.
Changes of the diastolic function of left ventry in patients with arterial hypertension in the process of micardis treatment in the family doctor's conditions
Authors: Koshlya V. I. , Kulbachuk O. S. , Sklyarova N. P. , Piskun A. V. , Solovyov O. V. 
Published: June 2019

Among 38 patients with arterial hypertension I and II degree, the diastolic function of the left ventricle was studied in the course of a twelve-month treatment with Telmisartan (Micardis). Analysis of the diastolic function of the left ventricle before the treatment with telmisartan showed that in both groups of patients with respect to the control group there was a significant decrease in the maximum speed of early diastolic filling and an increase in the maximum rate of atrial filling with increasing severity of the disease.
At the same time, the period of isovolumetric relaxation and the end diastolic pressure in the left ventricle increased, and the E/A and Ei/Ai ratios tended to decrease. At the end of the 12-month period of treatment with micardis, the achievement of target levels of blood pressure and normalization of diastolic function of the left ventricle were noted.
The platelet-rich plasma influence on the inflammatory process in proliferation stage
Authors: Sidoryako A. V. , Malanchuk V. A. , Barannik N. G. 
Published: June 2019

One of the known methods of treatment is biomesotherapy, in which the patient’s own biomaterials are used for injection. It ensures complete biocompatibility and practically eliminates the possibility of beginning the allergic reactions. One of the options for mesotherapy is the using of Plasmolifting TM (plasmolifting) – commercially patented title of PRP-therapy (Platelet Rich Plasma), which involves the using of an injection form of platelet-rich plasma.
Purpose of the study. Increase the efficiency treatment phlegmon of the maxillofacial area and neck with the help of impact of autoplasma rich in platelets on the proliferative phase.
Materials and methods. We carried out the diagnosis and complex treatment of 80 patients with odontogenic phlegmons who were hospitalized in the Department ofMaxillofacial Department. surgical and therapeutic dentistry State Institution «Zaporizhia Medical Academy of post-graduate education Ministry of Health of Ukraine». The patients were divided into 2 groups: 1st group – 25 patients, their treatment was carried out by the traditional method and 2nd group – 55 patients among whom platelet-rich plasma (PRP) was added to the treatment at the repair stage.
Conclusions. Treatment in this way accelerated the course of the healing process due to the additional reparative and proliferative effects of such therapy.
Arteriovenous forms of congenital vascular malformations of extremities: pathogenetic ground for modern approaches in treatment
Authors: Chernukha L. M. , Kashyrova O. V. , Vlaykov G. G. , Vlasenko O. A. , Gomolyako I. V. 
Published: June 2019

Purpose of the study. Improvement of the results of treatment of patients with arteriovenous forms (AVF) of congenital vascular malformations (CVM) of the extremities based on the development of the classification scheme of CVM and the study of proliferative activity of the pathology.
Materials and methods. The clinical data of 155 patients with AVF of CVM of extremities were analyzed in terms of observation from 1 month to 10 years. Patients of sex of men there were 65 (42%), women – 90 (58%), their correlation – 1 : 1,4; the average age was about 25,1 ± 10,4, children's age group – 53 (34%). The division into clinicalanatomical forms (11 groups) was carried out on the basis of the «working» classification scheme
«VASC + T». Expression proliferation markers VEGF and KI-67 woos study were performed by immunoperoxidase method with additional hematoxylin staining.
Results and discussion. Pathomorphological (66; 45,8%) and immunohistochemical studies (10; 7%) revealed the presence of proliferative activity of angiomatous tissues and degenerative changes in the walls of the vessels both due to developmental defects and disorders of hemodynamics, while the source of progression of the AVF of CVM there are vessels of the microvasculature.
Conclusions. The application of the CVM classification scheme and the step-by-step complex treatment approach, depending on the clinical and anatomical AVF of CVM, led to the absence of major postoperative complications. This tactic made it possible to achieve satisfactory long-term results in 136 (94,4%) cases.
DAMPAK KUALITAS LAYANAN DAN NILAI NASABAH TERHADAP KEPUASAN NASABAH PERBANKAN SYARIAH
Authors: Hamdani Hamdani 
Published: June 2019

Abstract: This research refers to studying service quality and customer value towards customer satisfaction in Islamic banking with a case study in PT Bank Syariah Mandiri Lhokseumawe Branch. The data used in this study are primary data through interviews using a questionnaire. The sample in this study was accidental sampling. The research method used is qualitative and quantitative methods, with multiple linear regression analysis. The results released by simultaneous shows, service quality and customer value have a positive and significant influence on customer satisfaction. While the results of the study indicate that, service quality has a positive and significant effect on customer satisfaction, the customer value also has a positive and significant influence on customer satisfaction. From the variable Quality of service and value of customers that are just the same as partial to customer satisfaction in Islamic banking. This research can be used as an evaluation and input for the management of a special sharia banking company, PT Bank Syariah Mandiri, Lhokseumawe Branch, to always improve service quality and value customers receive customers satisfied with services and benefits obtained or obtained by customers. Keywords: Service Quality, Customer Value, Customer Satisfaction
The Outcome of Vitrectomy in Acute Postoperative Endophthalmitis
Authors: Sembiring Sindy Boru , Aziza Yulia , Adriono Gitalisa Andayani 
Published: June 2019

Introduction: Twenty years ago, the results of Endophthalmitis Vitrectomy Study (EVS) were adapted worldwide as the standard management of endophthalmitis. The study suggested that there was no benefit of performing vitrectomy for acute postoperative endophthalmitis, unless for patients who presents with visual acuity of light perception. However, vitrectomy with advanced technology and technique has been changed rapidly in the last decades; therefore, we need to reconsider its role. We conducted a study and the purpose of our study was to describe the indications for vitrectomy and the outcomes in acute postoperative endophthalmitis at Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Methods: Our study was a descriptive-retrospective case series. We reviewed clinical and microbiological records of all patients with clinical diagnosis of acute postoperative endophthalmitis who underwent vitrectomy in Cipto Mangunkusumo Hospital between 2007 and September 2015. Presenting visual acuity, visual outcome and complications were described.
Result: Our study was a descriptive-retrospective case series. We reviewed clinical and microbiological records of all patients with clinical diagnosis of acute postoperative endophthalmitis who underwent vitrectomy in Cipto Mangunkusumo Hospital between 2007 and September 2015. Presenting visual acuity, visual outcome and complications were described.
Conclusion: An eight-year experience has taught us that vitrectomy offers better treatment outcome in the group with visual acuity of hand movement than those who only had visual acuity of light perception.
Bilateral Exudative Retinal Detachment Due to Hypertensive Retinopathy and Choroidopathy In Young Patient with Chronic Kidney Disease
Authors: Kartikasari Indha Dwi , Dewi Nadia Artha , Metita Mirza , Refa Safaruddin 
Published: June 2019

Introduction: Severe systemic hypertension in chronic kidney disease can cause significant damage to the eye. Although hypertensive retinopathy is a well-known complication, hypertensive optic neuropathy and choroidopathy are much less common. The aim of this study is to report retinal manifestation in young patient with chronic kidney disease.
Method: A 26-year-old man with underlying disease chronic kidney disease (CKD) gr-V underwent bilateral bullous exudative retinal detachments. Retinal arteriolar narrowing, vascular tortuosity, arteriovenous nicking, optic disc swelling, retinal haemorrhage, elschnig spot, siegrist streak were identified in both eyes. Blood pressure was 200/140mmHg with visual acuity 0,5/60 OU. The patient was diagnosed with bilateral hypertensive retinopathy and choroidopathy with bulous exudative retinal detachments.
Results: After antihypertensive treatment, visual acuity improved, but the exudative retinal detachments and retinal hemorrhages reduced. A patient with those findings should be considered as having hypertensive retinopathy and choroidopathy and treated as soon as possible because of the poor prognostic.
Conclusion: Hypertensive choroidopathy is a rare finding associated with acute increases in blood pressure. When the choroid is associated, the hypertensive event is often more acute and associated with increased morbidity. It is necessary to obtain fundus exam in any patient with elevated blood pressure and concomitant vision complaints. Therefore, screening hypertensive patients involves close collaboration between internist and ophthalmologist.