bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gynecology Cancer in Relationship with Obesity
Authors: Rauw Gracia M R G , Laihad Bismarck J , Affandi Biran 
Published: October 2018

Objective: To know the relationship between obesity and gynecology
cancer.
Method: This study use case control study design for 250 gynecology
patients (125 controls and 125 cases) in Prof. Dr. R. D. Kandou
Manado Hospital from 1 July to 30 November 2015. The data was
collected by measuring Body Mass Index (BMI) and filing out selfadministered
questioners.
Result: From the 250 subjects, the study group (125 subjects), 72
subjects have obesity (57.6%) and 97 subjects have multiple parities
(77.6%) with 58 subjects diagnosed with cervical cancer (46.4%). In
the control group (125 subjects), 71 subjects have normal weight
(56.8%) and 67 subjects have multiple parities (53.6%) with 64 subjects
diagnosed with ovarium cysts (51.2%). Using multivariate logistic
regression, the overweight and obese subjects have 7 folds
higher risk to develop gynecology cancer compared to those with
normal or underweight subjects. Those with multiple parities and
grande multipara subjects have 3 folds higher risk to develop gynecology
cancer compared with those who are nullipara and primipara.
Conclusion: A significant correlation is found between obesity and
gynecology cancer using multivariate logistic regression analysis
(p=0.000, OR=6.9 (95% CI = 3.62-13.13).
[Indones J Obstet Gynecol 2016; 1: 23-30]
Keywords: gynecology cancer, multiple parities, obesity
International Ovarian Tumor Analysis (IOTA) Scoring System to Predict Ovarian Malignancy Preoperatively
Authors: Feharsal Yuri , Putra Andi D 
Published: October 2018

Objective: To compare diagnostic performance of International
Ovarian Tumor Analysis (IOTA) scoring method with Risk of Malignancy
Index-4 (RMI-4) and Sassone Morphology Index to predict
ovarian malignancy preoperatively.
Method: Retrospective study with 119 subject who underwent surgical
removal of ovarian tumor and performed histopathological
examination at Dr. Cipto Mangunkusumo Hospital on January to
December 2013. Demographic status, ultrasound scans, CA-125
level and histopathological result were collected to calculate the
score of each method. Sensitivity, specificity, positive predictive
value, negative predictive value and accuracy were calculated by
comparing each score with histopathology result. Comparison of
diagnostic performance was analyzed by ROC curve.
Result: There were 51.26% subjects with benign tumor and 48.74%
subjects with malignant tumor. Result was analyzed with sensitivity
test (IOTA simple-rules, IOTA subgroup, RMI-4 and Sassone): 98%,
88%, 86% and 79%; specificity: 74%, 67%, 61% and 89%; positive
predictive value: 78%, 72%, 68% and 87%; negative predictive
value: 98%, 85%, 82% and 81%; and accuracy: 86%, 77%, 73% and
84%. AUC value for IOTA simple-rules, IOTA subgroup, RMI-4 and
Sassone were: 0.86, 0.78, 0.73 and 0.84. Comparison of these results
were significant with p = 0.000.
Conclusion: IOTA simple-rules had better sensitivity, negative predictive
value and accuracy than IOTA subgroup, RMI-4 and Sassone
morphology index to predict ovarian malignancy preoperatively.
[Indones J Obstet Gynecol 2016; 1: 42-46]
Keywords: iota, ovarian neoplasm, risk of malignancy, scoring
A1298C Polymorphism of Fetal Methylenetetrahydrofolate Reductase (MTHFR) Gene as a Risk Factor for Spontaneous Abortion
Authors: Sulfiana Isah , T Chalid St Maisuri , Farid Retno B , Rauf Syahrul , Hartono Eddy 
Published: October 2018

Objective: To investigate the role of A1298C polymorphism of fetal
methylenetetrahydrofolate reductase (MTHFR) gene in spontaneous
abortion.
Method: The case control study design recruited 96 subjects in Siti
Fatimah and Pertiwi mother and child hospital, Dr. Wahidin Sudirohusodo,
Pelamonia, Bhayangkara, Syekh Yusuf, Haji and Labuang
Baji hospital from March to September 2014. All subjects fulfilling
the inclusion criteria were taken tissue samples from mothers experiencing
spontaneous abortion and blood samples from normally
born baby. The data were analyzed using Pearson chi-square with
significant rate of 5% (p
Factors Related to the Number of Antral Follicles on InVitro Fertilization (IVF)
Authors: Raharja Fransiskus C , Suwiyoga Ketut , Wardhiana IPG 
Published: October 2018

Objective: To determine factors which are related to the number of
antral follicles on infertile patients.
Method: This cross sectional study was conducted in In-Vitro Fertilization
(IVF) clinic of Graha Tunjung, Sanglah hospital, Bali. All fertile
patients following the IVF program were calculated the number
of antral follicles in both ovarian using transgene USG. This sample
was recruited by random sampling from April 1st, 2001 to April 30th,
2011. We analyzed the data using Chi square test through SPSS for
Windows 17.0 version.
Result: Of 102 samples, the mean of patients’ age was 32.9% (SD
4.6) years old. From 72 patients (70.6%) experienced above 3 years
of infertile period, the primary infertile was on 69 patients (67.7%).
There was a relationship between patients’ age and the number of
antral follicles significantly (prevalence ratio (PR) 1.41; 95% CI 1.11-
1.79). Meanwhile, the number of antral follicles and type of infertile
(PR 1.02; 95% CI 0.76-1.37) also infertile period (PR 0.95; 95% CI
0.72-1.27) were not associated significantly.
Conclusion: Patients’ age has an association with the number of antral
follicles on IVF.
[Indones J Obstet Gynecol 2016; 4-2: 75-77]
Keywords: age, infertile, infertile period, number of antral follicles
and type of infertile
Postplacental IUD Insertion Using Ring Forceps versus Push and Push Technique
Authors: Tjahjanto Hary , Rizal Rahmad 
Published: October 2018

Objective: To compare IUD-endometrium (ED) distance and the incident
of malposition postplacental CuT-380A IUD insertion in vaginal
delivery between ring forceps technique and push and push
technique.
Method: This study was a double-blind randomized control trial,
performed in September 2014 until March 2015 at Dr. Kariadi Hospital.
Ring forceps and push and push insertion technique groups
consisted of 25 subjects in each group. Follow-up was performed at
1-2 weeks, 6-8 weeks and >12 weeks after insertion.
Result: The mean of IUD-ED distance in push and push group was
shorter (but not statistically significant) than ring forceps group. The
IUD-ED distance was at 1-2-week follow-up 4.1 (2.2) vs. 4.9 (3.4)
mm; p=0.208, at 6-8-week follow-up: 2.6 (1.8) vs. 3.2 (3.7) mm;
p=0.452, and at > 12-week follow-up: 0.9 (0.8) vs. 1.0 (0.9) mm;
p=0.427, respectively. Malposition was found in 1-2-week follow-up,
but the IUD was changed to the normal position (sagital position in
uterine fundus) at 6-8-week and >12-week follow-up. Up to 3
months of follow-up, there was no occurrence of perforation, expulsion
or pregnancy in both groups. Most of subjects (56% in the
ring forceps, 68% in push and push groups) did not feel painful during
IUD insertion.
Conclusion: Push and push insertion technique clinically tends to
produce IUD-ED distance shorter than ring forceps technique. Both
techniques are comfortable, safe and effective.
[Indones J Obstet Gynecol 2016; 4-2: 78-87]
Keywords: immediate postplacental IUD insertion technique, IUDendometrium
distance, IUD malposition, push and push technique,
ring forceps technique
Ovarian Tissue Vitrification as a Method for Ovarian Preservation in Women with Cancer: an Analysis of Granulose Cell Apoptosis
Authors: Wiweko Budi , Andriyana Huthia , Aulia Achmad 
Published: October 2018

Objective: To obtain the effective method of ovarian function preservation
with granulose cell apoptosis assessment. Ovarian tissue
vitrification became a method for ovarian function preservation in
women with cancer. This technique can be done anytime without
delay on cancer therapy both in prepubertal and unmarried patient.
It can also store many primordial follicles. Ovarian tissue vitrification
study is still limited to animal test and there are no data about apoptosis
assessment after ovarian vitrification in human ovary.
Method: This quasi experimental study was held in Department of
Obstetrics and Gynecology Faculty of Medicine University of Indonesia
- Dr. Cipto Mangunkusumo General Hospital and Fatmawati
Hospital Jakarta from March 2012 to May 2015. Ovaries from thirteen
women between 31 and 37 years old who underwent oophorectomy
with gynecological indication were examined.
Result: There was no morphological difference between follicles
from fresh and warmed-vitrified ovaries. The mean protein Bax
expression on the fresh ovaries assessed in the form of H-score
was 1.66 (SD 0.14) compared with 1.68 (SD 0.13) on the warmedvitrified
group (p=0.165). The mean protein Bcl-2 expression on the
fresh ovaries examined in the form of H-score was 1.73 (SD 0.10)
compared with 1.71 (SD 0.10) on the warmed-vitrified group
(p=0.068).
Conclusion: Ovarian tissue vitrification does not affect the Bax and
Bcl-2 expression on human ovary.
[Indones J Obstet Gynecol 2016; 4-2: 88-92]
Keywords: apoptosis, bax, Bcl-2, ovarian tissue vitrification
Bladder Function after Hysterectomy
Authors: Wijaya Johanna , Tendean Hermie , Laihad Bismarck J 
Published: October 2018

Objective: To determine the effect of hysterectomy on bladder function
pre- and post-radical hysterectomy in early stage of cervical
cancer.
Method: This study was a pre-post intervention study. Data were
collected through questionnaires from women who had radical hysterectomy
and total hysterectomy in Prof. Dr. R. D. Kandou Manado
general hospital and other networking hospitals since January 1st,
2014 to November 31st, 2014. We analyzed the data using Wilcoxon
and Mann-Whitney statistical test.
Result: There were each 18 respondents for the radical and total
hysterectomy group in Prof. Dr. R. D. Kandou general hospital and
networking hospitals. The age distribution of radical hysterectomy
was 41-45 years old for 44.4%. The parity was dominated by second
parity for 38.8%. In pre- and post-surgery, there were significant differences
for urinary incontinence disorder (p=0.003), emptying disorder
(p=0.008), urinary pain (p=0.034), and total urinary disorder
(p=0.001). While, between radical and total hysterectomy, there was
no significant difference in bladder function (p>0.05).
Conclusion: There is an association before and after surgery to urinary
function. However, there is no association between the radical
and total hysterectomy group.
[Indones J Obstet Gynecol 2016; 4-2: 97-100]
Keywords: bladder function, cervical cancer, radical hysterectomy
Epidemiology Data of Ovarian Cancer in Dr. Cipto Mangunkusumo Hospital, Jakarta
Authors: Noela Fransisca , Nuryanto Kartiwa H 
Published: October 2018

Objective: To describe the incidence of ovarian cancer and its characteristic
in Dr. Cipto Mangunkusumo Hospital in the last 5 years.
Method: This was cross sectional study design. The data was collected
from Gynecology Oncology Division Cancer Registry and Dr.
Cipto Mangunkusumo Hospital medical record from January 2009 to
December 2013; follow up was performed to know the 4-years survival
rate.
Result: There were 98 subjects in this study. The majority incidence
of ovarian cancer was 45-54 years old (33.6%); the incidence of
ovarian cancer decreased with the increased number of parity; the
majority histotype was epithelial (76.5%); and most of them were
diagnosed on advanced stage (55.1%). The 4-year survival rate for
epithelial type was 77%; germinal type was 83.3%; and stromal type
was 100%. Based on therapy, the 4-year survival rate was 84.1% for
surgical only; 83.3% in adjuvant chemotherapy group; and 68.4% in
neoadjuvant chemotherapy. In the group of adjuvant chemotherapy,
there was 63% patients with complete response and 41.2% patients
with complete response in neoadjuvant chemotherapy.
Conclusion: The highest incidence of ovarian cancer in Dr. Cipto
Mangunkusumo Hospital belongs to the age of reproductive women
(≤ 55 years old) with the highest incidence occurs in nulliparity women.
Most of the ovarian cancer cases are diagnosed in advanced
stage (stage III-IV).
[Indones J Obstet Gynecol 2016; 4-2: 101-106]
Keywords: age, histotype, ovarian cancer, parity, response, stage,
survival, treatment
The Characteristics of Preeclampsia with Severe Features
Authors: Adjie JM Seno , Lisnan Fredy , Sutandar Yosep 
Published: October 2018

Objective: To describe the characteristics of preeclampsia with severe
features and their risk factors.

Method: This study was a retrospective medical record review of
demographic characteristics, obstetric and medical data of preeclampsia
with severe features in Dr. Cipto Mangunkusumo Hospital
from July to December 2014.

Result: There were 1,013 deliveries which 183 patients of them
were diagnosed as preeclampsia with severe features (18.06%). The
study showed 67.76% were 20 - 35 years old, most of them were
multiparity, and 41.53% were preterm labor with 28 - 336 weeks of
gestation then followed by 24.59% were 34 - 366 weeks’ gestation.
Majorities of preeclampsia with severe features patients were without
complication either to the mother or the baby. There were 1 case
of maternal mortality and 15 cases of intra uterine fetal death
(IUFD). There were 73.77% cases delivering by cesarean section.
The complication of the mother in preeclampsia with severe features
was related significantly to the complication in baby, such as
preterm delivery. Besides, women’s age and parity had significant
relationship with baby complication.

Conclusion: There is association of complication in preeclampsia
with severe features women with baby, namely preterm delivery.
Besides, women’s age and parity is related to complication of baby.
Keywords: complication, preeclampsia, risk factors
The Outcome on Conservative Surgical Treatment of Adenomyosis
Authors: Wiweko Budi , Legiantuko Ario , Kemal Achmad , Pratama Gita , Situmorang Herbert , Sumapraja Kanadi , Natadisastra Muharam , Hestiantoro Andon 
Published: October 2018

Objective: To understand the outcome on conservative surgical
treatment of adenomyosis.

Methods: A retrospective cohort study followed for 2 years from
2010 to 2012 of women with adenomyosis were diagnosed by
transvaginal sonography and confirmed histologically. Subjects divided
into women who were treated by adenomyosis resection
(with/without Osada’s technique) and who were underwent hysterectomy.

Results: After the surgery, as many as 40 patients (81.63%) did not
feel any pain (VAS 0), and 9 patients (18.37%) still felt pain. For the
fertility outcome, we had 8 patients (20.51%) getting pregnant naturally
without any fertility intervention. Two patients (5.13%) had
successfully conceived by IVF. According to the type of surgery, from
8 natural pregnancy, 7 patients (87.50%) was underwent conventional
resection of adenomyosis and 1 patients (12.50%) underwent
Osada’s procedures. Two patients who were conceived by IVF, both
of them were underwent Osada’s resection.

Conclusion: Adenomyosis resection both conservative or Osada’s
procedures actually has a better outcome for relieving pain; therefore,
some patients can still have a child.

Keywords: adenomyosis resection, conventional resection, infertility,
Osada’s procedure
AntiMüllerian Hormone Level in Laparoscopic Cystectomy
Authors: Budipramana Edwin , Abdullah Nusratuddin , Tessy Telly 
Published: October 2018

Objective: To evaluate the impact of laparoscopic cystectomy using
cautery and suturing technique on the ovarian reserve represented
by the level of Anti-Müllerian Hormone (AMH) serum.

Method: This used prospective cohort study design conducted in
Dr. Wahidin Sudirohusodo Hospital, Department of Obstetrics and
Gynecology, Faculty of Medicine Universitas Hasanuddin, Makassar,
from November 2014 to October 2015. We got total samples of 60
subjects divided into cautery and suturing group. Anti-Mullerian
hormone serum test was examined on all subjects pre and post
laparoscopic cystectomy.

Result: The result indicated a significant decrease of AMH level
undergoing laparoscopic cystectomy both cautery and suturing
technique; whereas, more dominant results were showed in the
cautery group (p0.05).

Conclusion: The decline in the number of ovarian reserve as
described by the reduction of AMH level occurs significantly in both
cauterization and suturing technique, which are more dominant
reduction in the cauterization group.
[Indones J Obstet Gynecol 2016; 4-4: 203-207]

Keywords: Anti-Müllerian Hormone, laparoscopic cystectomy, ovarian
reserve
Medium-resolution Optical and Near-infrared Spectral Atlas of 16 2MASS-selected NIR-red Active Galactic Nuclei at z ∼ 0.3
Authors: Kim Dohyeong , Im Myungshin , Canalizo Gabriela , Kim Minjin , Kim Ji Hoon , Woo Jong-Hak , Taak Yoon Chan , Kim Jae-Woo , Lazarova Mariana 
Published: October 2018

Abstract
We present medium-resolution spectra (R ∼ 2000–4000) at 0.4–1.0 μm and 0.7–2.5 μm of 16 active galactic nuclei (AGNs) selected with red color in the near-infrared (NIR) of J − K > 2.0 mag at z ∼ 0.3. We fit the Hβ, Hα, Pβ, and Pα lines from these spectra to obtain their luminosities and line widths. We derive the E(B − V) color excess values of the NIR-red AGNs using two methods, one based on the line-luminosity ratios and another based on the continuum slopes. The two E(B − V) values agree with each other at rms dispersion ∼0.249. About half of the NIR-red AGNs have g′ − K < 5 magnitude, and we find that these NIR-red, but blue in optical-NIR AGNs, have E(B − V) ∼ 0, suggesting that a significant fraction of the NIR color-selected red AGNs are unobscured or only mildly obscured. After correcting for the dust extinction, we estimate the black hole (BH) masses and the bolometric luminosities of the NIR-red AGNs using the Paschen lines to calculate their Eddington ratios (λ
Edd). The median Eddington ratios of nine NIR-red AGNs (

) are only mildly higher than those of unobscured type 1 AGNs (

). Moreover, we find that the M
BH–σ
* relation for three NIR-red AGNs is consistent with that of unobscured type 1 AGNs at similar redshift. These results suggest that the NIR-red color selection alone is not effective at picking up dusty, intermediate-stage AGNs.
Modeling the Atomic-to-molecular Transition in Cosmological Simulations of Galaxy Formation
Authors: Diemer Benedikt , Stevens Adam R. H. , Forbes John C. , Marinacci Federico , Hernquist Lars , Lagos Claudia del P. , Sternberg Amiel , Pillepich Annalisa , Nelson Dylan , Popping Gergö , Villaescusa-Navarro Francisco , Torrey Paul , Vogelsberger Mark 
Published: October 2018

Abstract
Large-scale cosmological simulations of galaxy formation currently do not resolve the densities at which molecular hydrogen forms, implying that the atomic-to-molecular transition must be modeled either on the fly or in postprocessing. We present an improved postprocessing framework to estimate the abundance of atomic and molecular hydrogen and apply it to the IllustrisTNG simulations. We compare five different models for the atomic-to-molecular transition, including empirical, simulation-based, and theoretical prescriptions. Most of these models rely on the surface density of neutral hydrogen and the ultraviolet (UV) flux in the Lyman–Werner band as input parameters. Computing these quantities on the kiloparsec scale resolved by the simulations emerges as the main challenge. We show that the commonly used Jeans length approximation to the column density of a system can be biased and exhibits large cell-to-cell scatter. Instead, we propose to compute all surface quantities in face-on projections and perform the modeling in two dimensions. In general, the two methods agree on average, but their predictions diverge for individual galaxies and for models based on the observed midplane pressure of galaxies. We model the UV radiation from young stars by assuming a constant escape fraction and optically thin propagation throughout the galaxy. With these improvements, we find that the five models for the atomic-to-molecular transition roughly agree on average but that the details of the modeling matter for individual galaxies and the spatial distribution of molecular hydrogen. We emphasize that the estimated molecular fractions are approximate due to the significant systematic uncertainties.
Dynamic pricing for inventories with reference price effects
Authors: Chenavaz Régis , Paraschiv Corina 
Published: October 2018

Abstract
This article presents a dynamic pricing model of a retailer selling an inventory, accounting for consumer behavior. The authors propose an optimal control model, maximizing the intertemporal profit with consumers sensitive to the selling price and to a reference price. The optimal dynamic pricing policy is solved with Pontryagin’s maximum principle with a structural (general) demand function. The authors obtain an original pricing rule, which explicitly accounts for the impact of price and inventory on future profits. The dynamics of price do not have to imitate the dynamics of the reference price. Instead, the dynamics of price are tied to opposing effects linked to this reference price. The authors also discuss managerial implications with regards to behavioral pricing policies.
Screening for snow/snowmelt in SNPP VIIRS aerosol optical depth algorithm
Authors: Huang Jingfeng , Laszlo Istvan , Remer Lorraine A. , Liu Hongqing , Zhang Hai , Ciren Pubu , Kondragunta Shobha 
Published: October 2018

Abstract. The Visible Infrared Imaging Radiometer Suite (VIIRS) on board the Suomi
National Polar-orbiting Partnership (S-NPP) spacecraft provides validated
daily global aerosol optical depth (AOD) retrievals; however, a close
examination of the VIIRS aerosol product identified residual snow and
snowmelt contamination, resulting generally in an overestimation of AOD. The
contamination was particularly evident over Northern Hemisphere high-latitude
regions during the spring thaw. To improve the product performance, we
introduced a new empirical snow and snowmelt screening scheme that combines a
normalized difference snow index (NDSI)- and brightness temperature
(BT)-based snow test, a snow adjacency test and a spatial homogeneity test
(a.k.a. spatial filter). Testing of retrievals for 18 May 2014 indicated
that, compared to the previous, visible reflectance anomaly (VRA)-based snow
test, the new NDSI- and BT-based snow test screened out an additional
3.44 % of VIIRS AOD retrievals, most of which were over high latitudes
experiencing snowmelt. The new snow adjacency test and the homogeneity test
degraded another 5.57 % and 0.26 %, respectively, otherwise
“good”-quality AOD retrievals. For the VIIRS–AERONET (Aerosol Robotic
Network) matchups over Northern Hemisphere high-latitude regions during 3
years of spring (2013–2015), the new scheme also effectively screened out a
significant number of the matchups that had anomalously high positive biases
attributable to snow and snowmelt contamination. The new snow and snowmelt
screening scheme was transferred to the Interface Data Processing Segment
(IDPS) VIIRS aerosol algorithm on 22 June 2015. Subsequently no significant
snow and snowmelt contamination was found during spring 2016. The scheme is
also implemented in the new Enterprise VIIRS aerosol algorithm in the
National Oceanic and Atmospheric Administration (NOAA) Enterprise Processing
System (EPS) that became operational in 2017.