bluuebunny/crossref_metadata_2025_split huggingface dataset:
Partners and plagiarisers: dualities in consultants’ influence on organisational change projects
Authors: Shaw David 
Published: January 2019

Purpose
The purpose of this paper is to examine the interplay between the requirements for successful organisational change and the imperatives faced by management consultancy firms in running successful businesses, and how this interplay affects the ways in which management consultants influence organisational change projects.

Design/methodology/approach
The paper reviews literature on management consultancy and organisational change over the past 30 years to identify insights into this issue.

Findings
The paper shows that business imperatives faced by management consultancy firms affect the ways in which consultants influence organisational change projects. It shows how management consultants aspire to form strategic partnerships with their clients in order to win profitable business, and to plagiarise established organising practices and change management methods in defining their services in order to manage their costs. It illustrates how these aspirations give rise to a number of dualities that consultants face in undertaking organisational change projects.

Originality/value
Only limited research has been carried out into the ways in which the business imperatives of management consultancy firms interact with the requirements for successful organisational change in shaping the influence that management consultants have on organisational change projects. This paper demonstrates the significance of this issue and suggests directions for future research into it.
Supporting the mental health needs of young people: the spatial practices of school nurses
Authors: Sherwin Sarah Grace 
Published: January 2019

PurposeThe purpose of this paper is to raise awareness of an understanding of how school nurses work in multiple spaces, supporting young people in relation to promoting and protecting their emotional and mental health and wellbeing. It is argued that young people’s emotional health needs are still as prevalent today as they were over 150 years ago, when Charles Dickens wrote about them in the novelNicholas Nickleby.Design/methodology/approachSoja’s (1996) typology of spatial practice is applied to school nursing practice in an attempt to explore how different types of space influence how support is given to young people.FindingsExamples are provided from previous research (Sherwin, 2016) of how Soja’s theory of Firstspace, Secondspace and Thirdspace can be identified within school nurses’ practice, thereby providing an understanding of how school nurses provide support to young people on an everyday basis. It is proposed that in an addition Fourthspace also exists and a new conceptual model of spatial practice is proposed.Originality/valueSchool nurses have the potential to make a significant impact on preventing and protecting young people’s mental health. They provide valuable support to young people to enable them to cope with the complexities of their lives, yet relatively little is known about their everyday practice as this is an under-reported area of nursing. A new conceptual model is proposed to help provide an understanding of their practice.
Impact of corporate governance attributes on cost of equity
Authors: Srivastava Varnita , Das Niladri , Pattanayak Jamini Kanta 
Published: January 2019

Purpose
The purpose of this study is to construct a comprehensive Indian corporate governance index in light of the recently introduced Companies Act, 2013, which is further validated by analyzing its impact on the cost of equity of a firm.

Design/methodology/approach
Based on the hand-collected data from firms listed on S&P BSE 500 from 2001 to 2016, this index comprises seven equally weighted sub-indices, comprising a total of 43 corporate governance attributes. This index and the sub-indices have further been regressed with the cost of equity of a firm.

Findings
The results suggest a negative significant relationship between the overall corporate governance and the cost of equity. The study also suggests that among all the sub-indices, board composition predicts the cost of equity to a greater extent. Other than this, the audit committee sub-index has a negative significant association with the cost of equity. The findings imply that a well-governed firm enjoys ease of access to equity finance from the market.

Originality/value
The corporate governance index is based on the recent regulatory reforms introduced in India. The index, with certain changes suitable to the local context, can be applied to similar emerging economies as well. The causal relationship tested using this method is the first one done in India. This study adds to the domain of corporate governance literature with special focus on the construction of an index for an emerging economy.
Misuse of non-mandatory earnings reporting by companies
Authors: Howard Michael , Maroun Warren , Garnett Robert 
Published: January 2019

PurposeThe purpose of this paper is to examine the possibility of South African companies listed on the Johannesburg Stock Exchange (JSE) using adjusted earnings as a part of an impression expectation management strategy focused on demonstrating how reported earnings measures meeting or beating analysts’ earnings forecasts.Design/methodology/approachA multiple response analysis approach is used. Earnings adjustments are coded according to a defined typology and assessed for their status as either valid or invalid. The number of occurrences of adjusted earnings measures over a five year period (2010-2014) meeting or beating analyst forecasts is calculated.FindingsThe use of adjusted earnings by JSE listed companies is a common occurrence. There is evidence to suggest that this is used part of an impression expectation management strategy. Most of the adjustments are invalid. When otherwise valid adjustments are used in a particular year, these are frequently repeated, and when adjusted earnings are reported, these normally exceed analysts’ forecasts.Research limitations/implicationsThe paper is based on a relatively small sample from a single jurisdiction and limited time period. Nevertheless, the findings point to the need to revisit how financial performance is measured and reported, evaluate additional regulation to protect investors and understand in more detail exactly how and why companies use adjusted earnings as an impression expectation management tool.Originality/valueThe paper adds to the limited body of research on performance reporting outside of the USA and Europe. It also examines the use of adjusted earnings in a unique setting where, in addition to IFRS numbers, companies are required to report a mandatory adjusted earnings figure (headline earnings).
Joint effects of folate and vitamin B12 imbalance with maternal characteristics on gestational diabetes mellitus
Authors: Li Shuying , Hou Yaxing , Yan Xinxin , Wang Yuwen , Shi Chen , Wu Xiaoyan , Liu Huihuan , Zhang Liwen , Zhang Xumei , Liu Juan , Zhang Ming , Zhang Qiang , Tang Naijun 
Published: January 2019

AbstractBackgroundThis study examined whether folate and vitamin B12 imbalance is associated with gestational diabetes mellitus (GDM) and explored interactions between B vitamin imbalance and maternal risk factors for GDM.MethodsA cross‐sectional study was performed in 406 Chinese pregnant women. Serum folate, vitamin B12, and blood glucose concentrations were measured at 24 to 28 weeks gestation during GDM screening. A diagnosis of GDM was made based on International Association of Diabetes and Pregnancy Study Groups criteria (fasting plasma glucose [FPG] ≥5.1 mM, 1‐hour plasma glucose ≥10.0 mM, or 2‐hour plasma glucose ≥8.5 mM). Binary logistic regression was used to obtain odds ratios (ORs) after controlling for different confounders.ResultsHigher folate levels were associated with higher glucose concentrations and a higher risk of GDM (OR 1.98; 95% confidence interval [CI] 1.00‐3.90), whereas higher vitamin B12 levels were associated with lower FPG and a lower risk of GDM (OR 0.30; 95% CI 0.15‐0.60). A higher folate: vitamin B12 ratio was associated with higher glucose and a higher risk of GDM (OR 3.08; 95% CI 1.63‐5.83). The presence of both a higher folate: vitamin B12 ratio and advanced age further increased the OR to 2.13 (95% CI 1.09‐4.15) with a significant additive interaction. Furthermore, a higher folate: vitamin B12 ratio and a higher prepregnancy body mass index (pp‐BMI) were synergistically associated with an increased risk of GDM (OR 3.03; 95% CI 1.40‐6.57).ConclusionsAn imbalance between folate and vitamin B12, represented by a higher folate: vitamin B12 ratio, was highly associated with GDM risk, and this association could be further modified by maternal age and pp‐BMI.
Phylogenomics from low‐coverage whole‐genome sequencing
Authors: Zhang Feng , Ding Yinhuan , Zhu Chao‐Dong , Zhou Xin , Orr Michael C. , Scheu Stefan , Luan Yun‐Xia 
Published: January 2019

Abstract

Phylogenetic studies are increasingly reliant on next‐generation sequencing. Transcriptomic and hybrid enrichment sequencing techniques remain the most prevalent methods for phylogenomic data collection due to their relatively low demands for computing powers and sequencing prices, compared to whole‐genome sequencing (WGS). However, the transcriptome‐based method is constrained by the availability of fresh materials and hybrid enrichment is limited by genomic resources necessary in probe designs, especially for non‐model organisms.

We present a novel WGS‐based pipeline for extracting essential phylogenomic markers through rapid de novo genome assembling from low‐coverage genome data, employing a series of computationally efficient bioinformatic tools. We tested the pipeline on a Hexapoda dataset and a more focused Phthiraptera dataset (genome sizes 0.1–2 Gbp), and further investigated the effects of sequencing depth on target assembly success rate based on the raw data of six insect genomes (0.1–1 Gbp).

Each genome assembly was completed in 2–24 hr on desktop PCs. We extracted 872–1,615 near‐universal single‐copy orthologs (Benchmarking Universal Single‐Copy Orthologs [BUSCOs]) per species. This method also enables the development of ultraconserved element (UCE) probe sets; we generated probes for Phthiraptera based on our WGS assemblies, containing 55,030 baits targeting 2,832 loci, from which we extracted 2,125–2,272 UCEs. Resulting phylogenetic trees all agreed with the currently accepted topologies, indicating that markers produced in our methods were valid for phylogenomic studies. We also showed that 10–20× sequencing coverage was sufficient to produce hundreds to thousands of targeted loci from BUSCO sets, and an even lower coverage (5×) was required for UCEs.

Our study demonstrates the feasibility of conducting phylogenomics from low‐coverage WGS for a wide range of organisms without reference genomes. This new approach has major advantages in data collection, particularly in reducing sequencing cost and computing consumption, while expanding loci choices.
The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome
Authors: Cirakoglu Omer Faruk , Aslan Ahmet Oğuz , Akyuz Ali Riza , Kul Selim , Şahin Sinan , Korkmaz Levent , Sayın Muhammet Raşit 
Published: January 2019

AbstractBackground and aimNew‐onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACS). Also, Syntax score (SS) is a scoring system that is derived from angiographic images and is associated with long‐term mortality and major adverse cardiac events. In this study, we aimed to assess the relationship between SS and NOAF with known predictors of atrial fibrillation.MethodsIn a prospective, single‐center, cross‐sectional study, 692 patients who were diagnosed with coronary artery disease for the first time were enrolled consecutively. NOAF was defined as atrial fibrillation, which was documented after hospital admission. SS was calculated by a computer software. Multivariable logistic regression analyzes were used to detect the relationship between variables and NOAF.ResultsNew‐onset atrial fibrillation was detected in 82 patients (11.8%). Patients with NOAF had higher SS (22, interquartile range 18.3–25.1, vs. 12, interquartile range 7–19.5, p < 0.001). According to multivariable logistic regression analysis for NOAF, SS were independently and significantly associated (OR, 1.103; 95% confidence interval, 1.047–1.163; p < 0.001). Other independent predictors of NOAF were TIMI flow <3, C reactive protein, left ventricular ejection fraction, left atrial volume index and E/E′ ratio. The optimal cut‐off value for SS was 18 for the development of NOAF with 82% sensitivity and 68% specificity (area under the curve: 0.795, 95% confidence interval 0.749–0.841, p < 0.001).ConclusionSyntax score may be helpful to identify for patients who would develop atrial fibrillation in the setting of ACS.
Identification of a novel exon3 deletion of RYR2 in a family with catecholaminergic polymorphic ventricular tachycardia
Authors: Dharmawan Tommy , Nakajima Tadashi , Ohno Seiko , Iizuka Takashi , Tamura Shuntaro , Kaneko Yoshiaki , Horie Minoru , Kurabayashi Masahiko 
Published: January 2019

AbstractBackgroundRYR2, encoding cardiac ryanodine receptor, is the major responsible gene for catecholaminergic polymorphic ventricular tachycardia (CPVT). Meanwhile, KCNJ2, encoding inward‐rectifier potassium channel (IK1), can be the responsible gene for atypical CPVT. We recently encountered a family with CPVT and sought to identify a responsible gene variant.MethodsA targeted panel sequencing (TPS) was employed in the proband. Copy number variation (CNV) in RYR2 was identified by focusing on read numbers in the TPS and long‐range PCR. Cascade screening was conducted by a Sanger method and long‐range PCR. KCNJ2 wild‐type (WT) or an identified variant was expressed in COS‐1 cells, and whole‐cell currents (IK1) were recorded using patch‐clamp techniques.ResultsA 40‐year‐old female experienced cardiopulmonary arrest while cycling. Her ECG showed sinus bradycardia with prominent U‐waves (≥0.2 mV). She had left ventricular hypertrabeculation at apex. Exercise induced frequent polymorphic ventricular arrhythmias. Her sister died suddenly at age 35 while bouldering. Her father and paternal aunt, with prominent U‐waves, received permanent pacemaker due to sinus node dysfunction. The initial TPS and cascade screening identified a KCNJ2 E118D variant in all three symptomatic patients. However, after focusing on read numbers, we identified a novel exon3 deletion of RYR2 (RYR2‐exon3 deletion) in all of them. Functional analysis revealed that KCNJ2 E118D generated IK1 indistinguishable from KCNJ2 WT, even in the presence of catecholaminergic stimulation.ConclusionsFocusing on the read numbers in the TPS enabled us to identify a novel CNV, RYR2‐exon3 deletion, which was associated with phenotypic features of this family.
Atrial fibrillation in elderly patients with implantable loop recorders for unexplained syncope
Authors: Arcinas Liane A. , McIntyre William F. , Hayes Christopher J. , Ibrahim Omar A. , Baranchuk Adrian M. , Seifer Colette M. 
Published: January 2019

AbstractBackgroundAn implantable loop recorder (ILR) assists in the diagnosis of unexplained syncope and atrial fibrillation (AF). Both become prevalent with age. Limited data exist describing the incidence of AF as the diagnostic rhythm underlying syncope in the elderly. This study aims to report the incidence of AF in older adults with ILRs for unexplained syncope and identify clinical characteristics associated with AF in this population.MethodsRetrospective observational study on patients with unexplained syncope seen in syncope clinics from two Canadian centers. Participants were ≥65 years old, without a history of AF, and received an ILR for unexplained syncope. Data were collected from patient’s clinic charts. Arrhythmia diagnosis was based on ILR electrocardiogram reading during syncope (symptom–rhythm correlation). Fisher’s exact test and the Student’s t test were used to compare participants with and without AF.ResultsIn our cohort of 222 patients, 124 were females and 98 were males. Mean age at implant was 80 ± 8 years. Arrhythmia was diagnosed in 98 patients (44.1%). Median time to diagnosis was 18 months. AF was diagnosed in 17 (7.7%) participants. There were fewer males in the AF group than the no AF group (11.8%, 46.8%, p = 0.01). Age, baseline EKG, and prevalence of hypertension, diabetes, stroke, or ischemic heart disease were not statistically different between patients with AF and without AF.ConclusionsAtrial fibrillation was a common diagnostic rhythm in this cohort of adults, aged 65 and older, with ILRs for unexplained syncope. It was observed more frequently in females.
Active care of infants born between 22 and 26 weeks of gestation does not follow consensus expert recommendations
Authors: Sinclair Ruth , Bajuk Barbara , Guaran Robert , Challis Daniel , Sheils Joanne , Abdel‐Latif Mohamed E. , Hilder Lisa , Wright Ian M. , Oei Ju Lee 
Published: January 2019

AbstractAimTo determine the relationship between clinical practice and publication of an Australian consensus statement for management of extremely preterm infants in 2006.MethodsA population‐based study using linked data from New South Wales, Australia for births between 22 + 0 and 26 + 6 weeks of gestation between 2000 and 2011.ResultsThere were 4746 births of whom 2870 were liveborn and 1876 were stillborn. Of the live births, 2041 (71%) were resuscitated, 1914 (67%) were admitted into a neonatal intensive care unit (NICU) and 1310 (46%) survived to hospital discharge. Thirty‐nine (2%) stillbirths were resuscitated but none survived. No 22‐week infant survived to hospital discharge. Fewer 23‐week gestation infants were resuscitated between 2004 (52%) and 2005 (20%) but resuscitation rates increased by 2008 (44%). There was no difference at other gestations. Adjusted odds ratio (OR) for resuscitation was increased by birthweight (OR: 1.01), tertiary hospital birth (OR: 3.4) and Caesarean delivery (OR: 11.3) and decreased by rural residence (OR: 0.4) and male gender (OR: 0.7).ConclusionExpert recommendations may be shaped by clinical practice rather than the converse, especially for 23‐week gestation infants. Recommendations should be revised regularly to include clinical practice changes.
Contrasting vegetation change (1974–2015) in hedgerows and forests in an intensively used agricultural landscape
Authors: Van Den Berge Sanne , Tessens Sam , Baeten Lander , Vanderschaeve Cecile , Verheyen Kris 
Published: January 2019

AbstractQuestionsHow did hedgerows and forests change in area between 1974 and 2015 and did hedgerows still show the same vegetation composition in 2015? To what degree did the vegetation change in hedgerows and how do these changes compare to changes in forests? What is the nature of the species that changed and, from these, can we make general inferences about possible drivers of change?LocationThe countryside in the municipality of Turnhout, province of Antwerp, northern Belgium.MethodsThrough a resurvey of 54 and 20 quasi‐permanent plots in hedgerows and forests, respectively, we investigated shifts in the herb layer over the period 1974–2015. The plot‐level mean Ellenberg Indicator Values (EIVs) were calculated and soil samples were taken in 2015. We compared diversity statistics and used used Generalized Linear Mixed‐Effects Models (GLMMs) to detect trends in species richness (SR) and EIVs. Via a non‐metric multidimensional scaling (NMDS) ordination based on the Sørensen dissimilarity, we compared shifts at the community level.ResultsOur study shows severe, but opposite changes in SR in forests and hedgerows. In forests, SR declined and a homogenization occurred. The shifts in EIVs indicate that forest vegetation evolved to more shade‐tolerant and nutrient‐demanding species, likely due to eutrophication combined with natural forest succession. In hedgerows, SR significantly increased. The species pool became more diverse and more heterogeneous. Changes in EIVs suggest a change towards more light‐demanding species, possibly caused by fragmentation of the network, and towards species indicative for nutrient‐rich habitats, benefiting from eutrophication.ConclusionsIn general, SR in hedgerows is higher than in forests in our studied region, being a suitable habitat for a wide range of plant species in the countryside. However, the loss of almost 30% of the hedgerow habitat in 41 years confronts us with the challenge of protecting the hedgerow remnants, in the interest of agro‐biodiversity.
Reproduction and transformation of students’ technology practice: The tale of two distinctive secondary student cases
Authors: Beckman Karley , Bennett Sue , Lockyer Lori 
Published: January 2019

AbstractDisparities in the technology practices, skills and knowledge of school students still exist, despite widespread investment, and use in schools. In order to understand why inequalities remain, we first need a more nuanced understanding of students’ technology practice, including understanding how their backgrounds, circumstances and experiences shape their perceptions of and engagement with technology. This paper proposes that research in the field of educational technology would benefit from a sociological framing in order to highlight how and why students use technology at school and in their everyday lives. The paper reports on a qualitative embedded case study of 13–16‐year‐old students in two Australian secondary schools. In‐depth case studies of two selected students illustrate the complex nature of students’ technology practice. Bourdieu’s concepts of field, habitus and capital are used as a lens through which to view and understand inequalities in students’ technology practice. The findings demonstrate the utility of sociological theory in educational technology research by highlighting systems and structures of reproduction and transformation. Furthermore, the findings can inform an approach to teaching and learning that considers students’ varied experiences, knowledge, perspectives and backgrounds relating to technology.
Dysregulation of ß‐catenin, WISP1 and TCF21 predicts disease‐specific survival and primary response against radio(chemo)therapy in patients with locally advanced squamous cell carcinomas of the head and neck
Authors: Vyskocil Erich , Pammer Johannes , Altorjai Gabriela , Grasl Matthaeus Ch. , Parzefall Thomas , Haymerle Georg , Janik Stefan , Perisanidis Christos , Erovic Boban M. 
Published: January 2019

ObjectiveThe objective of this study was to determine the prognostic and predictive impact of β‐catenin, TCF21 and WISP1 expression in patients with squamous cell carcinomas of the head and neck who underwent primary radiotherapy or concomitant chemoradiotherapy.Study designProspective cohort study.SettingUniversity hospital.ParticipantsProtein expression profiles of β‐catenin, TCF21, WISP1 and p16 were determined by immunohistochemical analyses in tissue samples of 59 untreated patients. Expression was correlated with different outcome parameters.Main outcome measuresImpact of TNM classification, grading, sex, age, gender, type of therapy, response to therapy and p16 status on disease‐specific (DSS) and disease‐free survival (DFS).ResultsPatients with high expression of TCF21 were associated with significantly worse disease‐specific survival (P = 0.005). In a multivariable analysis, TCF21 was a significant determinant of disease‐specific survival. (HR 3.01; P = 0.036). Conversely, low expression of β‐catenin (P = 0.025) and WISP1 (P = 0.037) revealed a better response to radiotherapy.ConclusionSince data show that TCF21 is a prognostic factor for disease‐specific survival and WISP1 and ß‐catenin are predictive factors for clinical outcome after definitive radiotherapy, further studies are warranted to prove these preliminary but very promising findings.