bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current Research and Use of Mesenchymal Stem Cells in the Therapy of Autoimmune Diseases
Authors: Chen Youdong , Yu Qian , Hu Yifan , Shi Yuling 
Published: April 2019

:
Mesenchymal Stem Cells (MSCs) represent a heterogeneous group of self-renewal, multipotent
non-hematopoietic stem cells, which display profound immunomodulatory functions and promising
therapeutic effects. Autoimmune diseases, which result from an aberrant immune response to selfantigens,
can be detrimental to nearly all body tissues. With the advance in developing a novel treatment,
including biological agents, it is still impossible to cure autoimmune disorders. Recent studies demonstrate
the remarkable therapeutic effectiveness of MSCs towards a wide array of autoimmune diseases. In
this review, the immunomodulatory influence of MSCs over immune cells and the application of MSCs
transplantation in treating autoimmune diseases are highlighted.
A racionalização do sistema judicial no Brasil: desafios e perspectivas
Authors: Tavares Luiz Claudio Assis 
Published: April 2019

À medida que a necessidade de implementação de diretrizes nacionais exigiu a racionalização do sistema judicial para nortear a atuação institucional, fez também com que o Judiciário brasileiro incorporasse à sua agenda categorias até então desconhecidas. Em contrapartida, houve um incremento notável de suas funções “secundárias” de normatização e administração na tentativa de aperfeiçoar a prestação dos serviços judiciários. Essa nova realidade insere a racionalização do sistema judicial brasileiro em um contexto complexo, dinâmico e de intensas transformações, onde os atores não só disputam espaços como ganham diferentes papéis, impondo não somente novas demandas, mas, também, novas relações Palavras-chave: Reforma do Estado. Reforma Judiciária. Racionalização judicial.
Children Immunization App (CImA) Among Syrian Refugees in Zaatari Camp, Jordan: Protocol for a Cluster Randomized Controlled Pilot Trial Intervention Study
Authors: Khader Yousef S , Laflamme Lucie , Schmid Daniela , El-Halabi Soha , Abu Khdair Mohammad , Sengoelge Mathilde , Atkins Salla , Tahtamouni Manal , Derrough Tarik , El-Khatib Ziad 
Published: April 2019

Background
There are up to 19.4 million children who are still unvaccinated and face unnecessary deaths, especially among refugees. However, growing access to smartphones, among refugees, can be a leading factor to improve vaccination rates.

Objective
This study aims to determine whether a smartphone app can improve the vaccination uptake among refugees and determine the app’s effectiveness in improving the documentation of vaccination records.

Methods
We developed and planned to test an app through a cluster randomized trial that will be carried out at the Zaatari refugee camp in Jordan. The study will be open to all parents who carry Android smartphones, have at least one child, and agree to participate in the study. The parents will be recruited to the study by trained volunteers at the vaccination sites around the Zaatari camp. Inclusion criteria will be the following: having at least one child of 0 to 5 years, being a local resident of the camp, and having an Android smartphone.

Results
The intervention includes an app that will allow storing Jordanian vaccination records, per child, on the parents’ smartphones in Arabic and English (in an interchangeable fashion). Every record will have a set of automated reminders before the appointment of each child. The app will summarize immunization records in form of due, taken, or overdue appointments, labeled in orange, green, and red, respectively. Baseline will include the collection of our primary and secondary outcomes that are needed for the pre and postdata measurements. This includes social demographic data, any previous vaccination history, and electronic health literacy. Participants, in both study arms, will be monitored for their follow-up visits to the clinic for vaccination doses. For the study outcome measures, we will measure any differences in the uptake of vaccinations. The secondary outcome is to analyze the effect of the children immunization app on visits for follow-up doses.

Conclusions
Owing to the limited evidence of effective interventions for childhood vaccination among refugees, research in this area is greatly needed. The project will have a significant impact on the health of refugees and the public health system. In Jordan and the Middle East, the vaccination level is low. Given the influx of refugees from the area, it is crucial to ensure a high vaccination level among the children.

International Registered Report Identifier (IRRID)
PRR1-10.2196/13557
Paper and electronic versions of HM-PRO, a novel patient-reported outcome measure for hematology: an equivalence study
Authors: Goswami Pushpendra , Oliva Esther N , Ionova Tatyana , Else Roger , Kell Jonathan , Fielding Adele K , Jennings Daniel M , Karakantza Marina , Al-Ismail Saad , Lyness Jack , Collins Graham P , McConnell Stewart , Langton Catherine , Al-Obaidi Magda Jabbar , Oblak Metod , Salek Sam 
Published: April 2019

Aim:To determine measurement equivalence of paper and electronic application of the hematological malignancy-patient-reported outcome (HM-PRO), a specific measure for the evaluation of patient-reported outcomes in HMs.Patients & methods:Following International Society of Pharmacoeconomics and Outcomes Research ePRO Good Research Practice Task Force guidelines, a total of 193 adult patients with different HMs were recruited into a multicenter prospective study. The paper and the electronic version of the instrument were completed in the outpatient clinics in a randomized crossover design with a 30 min time interval to minimize the learning effect. Those who completed the paper version first, completed the electronic version after 30 min and vice versa. Instrument version and order effects were tested on total score of the two parts of the HM-PRO (Part A: quality of life and Part B: signs & symptoms) in a two-way ANOVA with patients as random effects. Intraclass correlation coefficients (95% CI) and Spearman's rank correlation coefficients were used to evaluate test–retest reliability and reproducibility. The effects of instrument version and order were tested on total score of the two parts of HM-PRO.Results:The questionnaire version and administration order effects were not significant at the 5% level. There were no interactions found between these two factors for HM-PRO (Part A [quality of life]; p = 0.95); and (part B [signs and symptoms]; p = 0.72]. Spearman's rank correlation coefficients were greater than 0.9, and intraclass correlation coefficients ranged from 0.94 to 0.98; furthermore, the scores were not statistically different between the two versions, showing acceptable reliability indexes. Noteworthy, the difference between the completion time for both paper (mean = 6:38 min) and electronic version (mean = 7:29 min) was not statistically significant (n = 100; p = 0.11). Patients did not report any difficulty in completing the electronic version during cognitive interviews and were able to understand and respond spontaneously.Conclusion:Measurement equivalence has been demonstrated for the paper and electronic application of the HM-PRO.
La experiencia de tutoría académica en el Bachillerato Universitario a Distancia de la UAEMéx, en los Centros de Prevención y Readaptación Social
Authors: Panchi-Vanegas Virginia Pilar , Vega-Mondragón Belem 
Published: April 2019

<p>En atención a la responsabilidad y la obligatoriedad nacional de la Educación Media Superior, la Universidad Autónoma del Estado de México y la Comisión Estatal de Seguridad Ciudadana de la entidad mexiquense recientemente firmaron el convenio para proporcionar el servicio educativo del Bachillerato Universitario a Distancia a los <em>internos </em>de los Centros de Prevención y Rehabilitación Social (CPRS). </p><p>Se comparte en este trabajo la experiencia y la problemática enfrentada por la UAEMéx al atender a una población que se encuentra bajo restricción de libertad y limitación de los servicios educativos que influyen en su proceso de aprendizaje. Estos aspectos obligaron a desplazar la función tutorial propia del programa educativo y asumir el reto de una tutoría para grupos vulnerables que incorpora la labor ejercida por los responsables de sede como figura de acompañamiento para estudiantes de los Centros Penitenciarios de Readaptación Social, establecida operativamente, basada en el perfil especializado de tutores, así como en el trabajo colegiado de diseñadores y asesores de Guías de Estudio Independiente.</p>
PENGEMBANGAN MEDIA POP CULTURE UP RUMAH ADAT JAWA UNTUK PEMBELAJARAN MENYUSUN TEKS DESKRIPSI PADA PESERTA DIDIK SMP KELAS VII
Authors: Ambarsari Dewi Woro , Hartono Bambang 
Published: April 2019

Tujuan penelitian ini adalah mendeskripsi karakteristik kebutuhan media pop culture up rumah adat Jawa untuk pembelajaran menyusun teks deskripsi pada peserta didik SMP kelas VII, mengembangkan media, dan mendeskripsikan penilaian ahli terhadap media pop culture up rumah adat Jawa untuk pembelajaran menyusun teks deskripsi pada peserta didik SMP kelas VII. Penelitian ini dilakukan dengan menggunakan pendekatan Research and Development (R&D). Sumber data penelitian ini adalah siswa, guru, dan dosen ahli. Teknik pengumpulan data kebutuhan penelitian ini menggunakan kuesioner. Teknik analisis data menggunakan teknik analisis deskriptif kualitatif. Hasil penelitian ini adalah didapatkannya karakteristik kebutuhan media pop culture up rumah adat Jawa untuk pembelajaran menyusun teks deskripsi: (1) aspek penyajian isi/materi adalah penyajian gambar pop up beserta keterangan bagian-bagianya dan cara menyusun teks deskripsi; (2) aspek bahasa dan keterbacaan disesuaikan dengan kemampuan peserta didik; (3) aspek tampilan 2D, perpaduan warna, serta jenis huruf disesuaikan. Penilaian terhadap media pop culture up rumah adat Jawa: (1) aspek grafika mendapat nilai 79,1 dengan kategori baik, (2) aspek penyajian isi/materi mendapat nilai 75,2 dengan kategori baik, dan Â (3) aspek bahasa dan keterbacaan mendapat nilai 81,6 dengan kategori sangat baik.
BAHASA SARKASME NETIZEN DALAM KOMENTAR AKUN INSTRAGRAM â€œLAMBE TURAHâ€
Authors: Inderasari Elen , Achsani Ferdian , Lestari Bini 
Published: April 2019

Perkembangan teknologi informasi dan komunikasi yang semakin pesat menunjukkan bahwa masyarakat semakin canggih dalam pemanfaatan. Pemanfaatan media sosial sekarang seakan tanpa batas, pola ketergantungan yang tinggi memberikan dampak positif dan negatif, misalnya dapat kita temui di situs jejarang sosialÂ salah satunya Instagram. Melalui jejaring sosial Instagram, netizen dapat dengan mudah menyebar luaskan informasi dan memperoleh informasi secara cepat dan tepat. Namun tidak dapat dipungkiri berbagai dampak yang bisa ditimbulkan karena pola tanggapan masing-masing netizen selaku pengguna medsos yang berbeda-beda, misalnya munculnya penggunaan bahasa sarkasme yang menyebabkan adanya pelanggaran prinsip kesantunan berbahasa. Penelitian ini bertujuan mendeskripsikan penggunaan bahasa sarkasme komentar netizen dalam akun instragram Lambe Turah serta faktor-faktor yang mempengaruhinya. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif. Sumber data dalam penelitian ini adalah komentar netizen dalam akun Instragram Lambe Turah. Teknik pengumpulan data dalam penelitian ini menggunakan teknik catat, dengan mencatat setiap komentar yang melanggar penggunaan prinsip kesantunan berbahasa yang di munculkan netizen di dalam akun. teknik keabsahan data dalam penelitian ini berupa triangulasi teori, analisis data mengunakan analisis interaktif, pengumpulan data komentar netizen dari akun Lambe Turah.Â Hasil penelitian menunjukkan bahwa penggunaan bahasa sarkasme komentar netizen dalam akun instragram Lambe Turah menyebabkan adanya pelanggaran prinsip kesantuanan berbahasa yang meliputi maksim kebijaksanaan, kemurahatian, penerimaan, kerendahatian, kecocokan dan kesimpatian. Faktor-faktor yang memengaruhinya yakni,Â penutur ingin menunjukkan eksistensi diri, meluapkan ekspresi atau emosi, komunikasi searah, Kebebasan bersosial media, dan adanya kecenderungan sifat yang sama antara apa yang netizen tunjukkan di media sosial dengan perilaku keseharian mereka.
Direct Composite Resin Veneers in Nonvital Teeth: A Still Viable Alternative to Mask Dark Substrates
Authors: Yanikian CRF , Yanikian F , Sundfeld D , Lins RBE , Martins LRM 
Published: April 2019

SUMMARY
Direct composite resin veneers are a practical esthetic restorative treatment for reestablishing the shape and color of affected anterior teeth. The present clinical case reports aim to describe restorative treatment techniques for nonvital anterior teeth presenting color alteration. The direct composite resin layering technique has proven to be an efficient method for recovering the esthetics of darkened teeth. The direct vs indirect restorative treatments are debated as well. Clinical follow-ups of the presented case reports demonstrate that direct composite resin restorations are not affected by the darkened tooth substrate over time.
ANALISIS KINERJA PACKET FILTERING BERBASIS MIKROTIK ROUTERBOARD PADA SISTEM KEAMANAN JARINGAN
Authors: Muzakir Ari , Ulfa Maria 
Published: April 2019

Pada penelitian ini fokus pada ujicoba kinerja jaringan komputer dari sisi sistem keamanan jaringan. Ujicoba sendiri dilakukan pada jaringan komputer yang ada di Laboratorium Komputer di Universitas Bina Darma menggunakan sistem operasi Mikrotik. Adapun hasil akhir yang diharapkan melalui penelitian ini yaitu untuk melihat secara komprehensif kemampuan packet filtering yang terdapat di mikrotik routerboard dalam mengatasi masalah keamanan jaringan komputer. Keamanan jaringan yang dimaksud adalah kemampuan pada proses pemblokiran URL http dan https. Pada ujicoba yang dilakukan, filtering rule mampu melakukan blok url yang ada pada protocol HTTP maupun HTTPS yang mana membuktikan bahwa kinerja dari filtering rule cukup baik. Dalam menganalisis kinerja packet filtering menggunakan tool network packet anayzer Wireshark dengan cara melakukan capture paket yang lewat didalam jaringan dan menampilkan semua informasi secara detil. Hasil akhir yang didapatkan dalam proses simulasi sistem keamanan jaringan menggunakan wireshark adalah setiap paket yang dikirim tidak dapat dibaca (blokir) baik pada protocol http maupun https. Kinerja dari tools disebuah router mikrotik tidak menjamin keamanan yang baik, efektivitas keamanan tergantung pada kemampuan administrator dalam mengkonfigurasi sebuah keamanan tersebut.
Penentuan Tingkat Kerusakan Lahan pada Berbagai Bentuk Penggunaan Lahan di Daerah Gumelar, Kabupaten Banyumas Jawa Tengah
Authors: Prasmaji Prasmaji , Kusuma Ruly Eko , Suwardi Suwardi , Prihastuti Prihastuti 
Published: April 2019

Land degradation represents a form of land productivity decrease that occurs due to the presence of incompatible land usage with land characteristic, which resulted in land capacity deterioration. Land degradation evaluation is determined based on Government Regulation No.150/2000 regarding land degradation control for biomass production, and Living Environment Minister Regulation No. 7/2006 for criteria standardization on soil measurement of biomass production. This research was conducted to evaluate land degradation levels based on physical characteristics of several land use patterns in Gumelar Region. The research used a survey method with homogenous land unit (HLU). HLU approaches were obtained from overlay between land use map and slope map. The measured parameters were i.e. solum thickness, surface rockiness, soil texture, bulk density, porosity and permeability. Results of the samples analysis were compared with the parameters values on Goverment Regulation No. 150/2000. The results of the research showed 69,7% of the total area of Gumelar had undergone land degradation. Garden land use contributed 51.5% land degradation, which was divided into several classes i.e. good and slight damage potential was 12.0%, slightly damaged was 17.7%, slightly damaged with damage potential was 4.8%, and damaged was 17.1%. Dry land contributed to damaged land degradation of 11.3%, and categorized entirely as slightly damaged, while the shrub land use contributes 6.9% of degraded land (with 2.8% and 4.1% were good with slight damage potential and slightly damaged with damage potential, respectively). Largest contribution of land damage towards land degradation was dry land, all dry land in study area were in slightly damaged condition. Garden was the land use with lowest land degradation, which indicates the most suitable land use in the studied area was garden. Keywords: land use, land degradation, homogenous land unit, overlay
LIBRO DE RESÃ?MENES TALLER II: Problemas, interrogantes y soluciones en el estudio de la tecnología lítica
Authors: Hermo Darío Omar 
Published: April 2019

Libro de resúmenes de los trabajos presentados en el TALLER II: Problemas, interrogantes y soluciones en el estudio de la tecnología lítica, realizado el 9 de junio de 2017 en el marco del CICLO DE TALLERESDE LA DIVISIÃ?N ARQUEOLOGÍAMUSEO DE LA PLATA, FACULTAD DE CIENCIAS NATURALES Y MUSEO.
Cambios climáticos en la región pampeana oriental durante los últimos 1000 años. Una síntesis con énfasis en la información zoogeográfica.
Authors: Tonni Eduardo Pedro 
Published: April 2019

Se realiza una síntesis de la información zoogeográfica provista especialmente por los mamíferos, con relación a los cambios climáticos durante los últimos 1000 años en la región pampeana oriental. Durante el Máximo Térmico Medieval (MTM) el registro de los mamíferos indica temperaturas más altas que las actuales; esta condición produce el desplazamiento hacia el sur de micromamíferos chaqueños. La Pequeña Edad de Hielo (PEH) fue definida en la Argentina casi exclusivamente a través de observaciones faunísticas en la pampa oriental. El registro faunístico indica condiciones semiáridas a áridas con temperaturas más bajas que las actuales; estas condiciones son más frecuentes y significativas desde el siglo XVIII hasta la segunda mitad del siglo XIX. En años recientes se observó en la región pampeana, la ampliación de los límites de distribución austral de numerosas especies vegetales y animales; esta modificación se atribuye al incremento en la temperatura.
Evaluation of team effectiveness and personal empathy for associations with professional quality of life and job satisfaction in companion animal practice personnel
Authors: Pizzolon Christina N. , Coe Jason B. , Shaw Jane R. 
Published: April 2019

Abstract

OBJECTIVE
To examine variables of veterinary team effectiveness and personal empathy for associations with professional quality of life (ie, compassion satisfaction, burnout, and secondary traumatic stress) and job satisfaction in companion animal practice personnel.

DESIGN
Cross-sectional survey.

SAMPLE
Data from 232 surveys completed by personnel from 10 companion animal veterinary practices in 2 regions of the United States between April 7 and December 20, 2016.

PROCEDURES
Online surveys were used to collect practice-level data (eg, practice type, setting, and staffing) and individual-level data (eg, demographics, job position, and years in the position and profession). Instruments used in developing the surveys included the Team Effectiveness Instrument, Davis Interpersonal Reactivity Index, Professional Quality of Life Scale, and a measure for job satisfaction. Data were evaluated for associations with professional quality of life and job satisfaction.

RESULTS
Individual engagement was positively associated with job satisfaction, negatively associated with secondary traumatic stress, and moderated by levels of personal distress for compassion satisfaction and burnout. Toxic team environment was positively associated with burnout and negatively associated with job satisfaction. Empathetic concern and personal distress were both positively associated with secondary traumatic stress. Empathetic concern was moderated by team engagement for compassion satisfaction.

CONCLUSIONS AND CLINCAL RELEVANCE
Results indicated that variables influencing professional quality of life and job satisfaction were multimodal and included aspects of team effectiveness and empathy; therefore, workplace strategies that enhance individual and team engagement and mitigate toxic team environments could potentially improve professional quality of life and job satisfaction in veterinary personnel.
Computable Variants of AIXI which are More Powerful than AIXItl
Authors: Katayama Susumu 
Published: April 2019

Abstract
This paper presents Unlimited Computable AI, or UCAI, that is a family of computable variants of AIXI. UCAI is more powerful than AIXItl, which is a conventional family of computable variants of AIXI, in the following ways: 1) UCAI supports models of terminating computation, including typed lambda calculi, while AIXItl only supports Turing machine with timeout ˜t, which can be simulated by typed lambda calculi for any ˜t; 2) unlike UCAI, AIXItl limits the program length to some ˜l .
Continuum eclético, disciplina distinta ou subdomínio dos estudos de comunicação? Considerações teóricas e conclusões empíricas a respeito da disciplinaridade, multidisciplinaridade e transdisciplinaridade dos estudos de jornalismo
Authors: Löffelholz Martin , Rothenberger Liane 
Published: April 2019

Os estudos de jornalismo são um subdomínio dos estudos decomunicação, uma disciplina distinta, uma fusão multidisciplinar ou uma tentativa transdisciplinar? Discute-se esta questão, neste artigo, através da análise dos volumes de 2008 e 2009 de sete publicações acadêmicas que focalizam a pesquisa em jornalismo. A amostra inclui 349 artigos publicados na Brazilian Journalism Research, Ecquid Novi: African Journalism Studies, Journalism & Communication Monographs, Journalism & Mass Communication Quarterly, Pacific Journalism Review, Journalism Studies e Journalism: Theory, Practice and Criticism. De modo geral, as conclusões revelam que a pesquisa em jornalismo utiliza principalmente as abordagens teóricas e os métodos empíricos derivados de outras disciplinas, especialmente da sociologia, da psicologia e dos estudos culturais. Entretanto, em muitos países os estudos de jornalismo já alcançaram um nível comparativamente alto de institucionalização, indicado pelo grande número das escolas específicas, dos cargos de professor, das associações profissionais e das respectivas publicações acadêmicas. Concluímos por defender a tese de que os estudos de jornalismo são um subdomínio dos estudos de comunicação que integra e transcende várias disciplinas visando se tornar uma das matérias mais importantes do século XXI.
Eleições municipais nas primeiras páginas dos jornais diários: Comparação entre produção jornalística em periódicos de municípios com conjunturas políticas diferentes e seus efeitos para a democracia de massa
Authors: Cervi Emerson Urizzi 
Published: April 2019

O texto discute as chamadas de primeiras páginas sobre disputas eleitorais municipais de 2008 em jornais diários brasileiros. São analisadas as primeiras páginas de dois periódicos: Gazeta do Povo e Jornal da Manhã. O primeiro tem abrangência regional e sede em Curitiba, capital do Paraná. O segundo tem circulação local e uma área de abrangência restrita a uma região do interior do Estado do Paraná. Para fins comparativos, avalia-se que tipo de visibilidade ganha o tema Eleições Municipais nesses dois periódicos. Espera-se identificar a importância da campanha eleitoral nos jornais. Trata-se de uma discussão sobre o papel da mídia na difusão de informações politicamente relevantes, considerando distinções de contexto eleitoral. Enquanto em Curitiba o atual prefeito foi reeleito no primeiro turno com quase 80% dos votos, indicando uma ausência de disputa eleitoral de fato, em Ponta Grossa o candidato à reeleição venceu no segundo turno e com uma vantagem de menos de 4% de votos válidos sobre o segundo colocado. A questão que se coloca no texto gira em torno da necessidade de se considerar o contexto social para a explicação da produção jornalística.