bluuebunny/crossref_metadata_2025_split huggingface dataset:
Model Persepsi Penggunaan Media Sosial pada Perkuliahan dengan Modifikasi Task Technology Fit dan Expectation Confirmation Theory
Authors: Kurniabudi Kurniabudi , Assegaff Setiawan 
Published: May 2019

Penerimaan teknologi informasi di bidang pendidikan menjadi hal yang menarik untuk dibahas. Keberhasilan implementasi teknologi informasi untuk mendukung pembelajaran tergantung pada penggunaan berkelanjutan. Diyakini bahwa ini dipengaruhi oleh kepuasan dan pemilihan teknologi yang digunakan. Facebook adalah media sosial paling populer di kalangan para siswa. Penelitian ini bertujuan untuk mengusulkan model kepuasan dan task-fit perceptions dari penggunaan media sosial dalam pendidikan. Penelitian ini dilakukan dengan membahas tentang kerangka teori, identifikasi faktor, mengembangkan model dan instrumen penelitian. Studi ini mengusulkan model yang dikembangkan dengan mengadopsi Task Technology Fit dan Expectation-Confirmation Theory. Untuk membangun model itu, lima konstruk telah dipilih seperti persepsi kesesuaian tugas, pemanfaatan, kualitas layanan, kepuasan dan konfirmasi atas niat untuk terus menggunakan teknologi. Selain itu, mendasari teori yang digunakan dalam penelitian ini beberapa hipotesis telah dirumuskan.
Sistem Retribusi Parkir Sebagai Pengawasan Pendapatan Asli Daerah Kabupaten Cilacap
Authors: Vikasari Cahya 
Published: May 2019

Retribusi yang dapat dikelola oleh daerah yaitu retribusi jasa yang didalamnya terdapat pengelolaan retribusi pelayanan kesehatan, retribusi parkir, retribusi pasar. Dinas perhubungan sulit mengetahui informasi tentang hutang setoran retribusi, administrasi data parkir belum tersimpan dengan baik sehingga sulit melakukan pengawasan terhadap penerimaan pendapatan daerah, kurang efisien dari segi waktu dalam penyusunan laporan. Sistem yang dibangun untuk mengatasi masalah penerimaan dana retribusi dibuat berbasis client server dan dengan konsep UML (Unified Modeling Language) yaitu dengan diagram usecase, sequence diagram dan class diagram serta pembangunan perangkat lunak yang digunakan yaitu menggunakan metode waterfall. Hasil dari penelitian ini adalah sistem dapat digunakan sebagai pengawasan penerimaan pendapatan asli daerah kabupaten Cilacap, membantu dalam pengolahan transaksi retribusi secara akurat dan up to date serta dapat menampilkan laporan transaksi perparkiran sebagai data dukung dalam pengambilan kebijakan khususnya dibidang retribusi parkir.
Kesiapan Mengadopsi Sistim Informasi Pada Rumah Sakit Pemerintah di Kota Padang
Authors: Pujani Vera , Sermiaty Rima , Tri Wahyu Kotama Dede 
Published: May 2019

Studi ini bertujuan untuk mengevaluasi pengaruh faktor kesiapan rumah sakit daerah milik pemerintah di kota Padang dalam mengadopsi E-health atau sistim informasi manajemen rumah sakit. Faktor kesiapan yang akan diukur adalah adanya kesiapan pokok (core), kesiapan structural teknologi (structural), kesiapan social (societal), kesiapan untuk menggunakan (engagement), upaya yang dilakukan (effort), dan capaian kinerja (performance) terhadap adopsi e-health. Penelitian ini menggunakan metode kuantitatif dan survey terhadap 80 orang pengguna sistim informasi pada tiga rumah sakit pemerintah di Kota Padang. Pemilihan sampel berdasarkan metode purposive sampling, karena hanya dtujukan bagi yang pernah mengoperasikan sistim informasi di rumah sakit. Data yang diperoleh dari kusioner akan diolah menggunakan analisis regresi berganada dengan aplikasi Stata. Studi ini menguji 6 hipotesis dan menghasilkan bahwa semua faktor kesiapan mempengaruhi adopsi e-health di rumah sakit milik negara di Kota Padang. Dari semua variabel diteliti, ditemukan rata-rata tertinggi pada variabel capaian kinerja, artinya rumah sakit yang bisa mengadopsi e-health, mesti memiliki kinerja yang baik juga. Implikasi dan saran di jelaskan pada bagian akhir dari penelitian ini. Untuk studi lanjut mesti dipertimbangkan factor lain seperti komitmen pimpinan, dan keersediaan dana dalam mengadopsi e-health di rumah sakit pemerintah di Indonesia.UMMI untuk melakukan manajemen risiko.
COMPARATIVE ANALYSIS OF ACTOPROTECTIVE PROPERTIES OF NEW CHEMICAL COMPOUNDS
Authors: Stratienko Elena N. , Katunina Natalia P. , Tseeva Fatima N. , Kukhareva Oksana V. , Uvarov Alexander V. , Galenko-Yaroshevsky Pavel A. , Kiselev Alexander V. , Ovsyanikova Anna G. 
Published: May 2019

Aim. This study was aimed at searching and investigating new substances among phenylethyl derivatives of 3-hydroxypyridine, which exhibit a high actoprotective activity under the conditions of normoxia and acute hypobaric hypoxia.Materials and methods. New compounds of phenylethyl derivatives of 3-hydroxypyridine under the SC code (n = 23) were investigated in comparison with bemethyl and bromantane. The actoprotective activity of new compounds was assessed in experimental animals using a treadmill running test under the conditions of normoxia and acute hypobaric hypoxia. The studied chemical substances and comparative drugs were administered 1 hour prior to exposure of animals to the test. Statistical processing of the obtained experimental results was performed using Microsoft Excel and Statistica for Windows 6.0 software.Results. Among the studied substances, active compounds exhibiting an actoprotective effect have been distinguished. SC-119 chemical substance was revealed, which exceeds the other studied chemicals and bemethyl and bromantane reference actoprotectors in terms of the range of effective doses and actoprotective activity under the conditions of normoxia and acute hypobaric hypoxia.Conclusion. According to the results of the study, the SC-119 compound seems to be a prospective candidate for further research into highly effective actoprotective drugs.
PATHOGENETIC ASPECTS OF METABOLIC SYNDROME IN WOMEN OF REPRODUCTIVE AGE (A LITERATURE REVIEW)
Authors: Kastueva Nina D. , Tsidaeva Tatyana D. , Belikova Zalina F. , Maysuradze Liana V. 
Published: May 2019

Aim. The aim of this work was to analyze recently published data on the risk factors and pathogenetic aspects of metabolic syndrome (MS) in women of reproductive age.Materials and methods. This review covers data presented in foreign and Russian literature, which has been published in electronic bibliographic databases Pubmed and the Cochrane Library over the past 10 years. Specifi cally, we carried out an analysis of works containing information on risk factors, pathogenetic aspects and diagnostic criteria of MS in women of reproductive age, as well as on methods currently used for the treatment of this condition.Results. We characterize modern theories that explain mechanisms triggering the development of MS complicated with diabetes 2 type and polycystic ovary syndrome (PCOS). Data on proteomic markers refl ecting the complex pathogenesis of PCOS is generalized, along with their role in the diagnosis and treatment of this disease. The possibility of using these markers for predicting pregnancy outcomes is shown. The importance of regulating metabolic processes for the preparation of women for pregnancy and fertility recovery is emphasized.Conclusion. Hyperandrogenism, insulin resistance, obesity, diabetes 2 type, dyslipidemia, PCOS are shown to be the most signifi cant factors determining pathological changes in fertile age women with metabolic syndrome. The correction of these factors should be included in the course of pregravid preparation for the prevention of adverse pregnancy outcomes.
ANALGESIC NEPHROPATHY. A MODERN VIEW ON THE PROBLEM
Authors: Poselugina Olga B. 
Published: May 2019

Aim. To review Russian and foreign literature on modern methods of diagnosis and treatment of patients with analgesic nephropathy.Materials and methods. Russian and foreign literature sources published in recent years on the aforementioned problem were analyzed.Results. This article presents the concept of analgesic nephropathy (AN) and discusses causes and mechanisms of its development. The pathogenic effect of non-steroidal antiinfl ammatory drugs on renal tissue is indicated. Key stages of the disease and its clinical features are determined. An algorithm of diagnosis is proposed. The importance of a patient’s detailed medical history is emphasized, including the duration, multiplicity and reasons for taking analgesics. A particular attention is paid to questions of AN therapy and its prevention. Provided timely diagnosis and analgesics withdrawal, the possibility of reverting tubulointerstitial infl ammation is shown.Conclusion. It is shown that optimal solutions with regard to AN diagnosis and its treatment are yet to be found. A timely diagnosis inhibits the development of chronic renal failure, which early detection provides for a higher treatment effi ciency and improved prognosis.
MODERN TREATMENT OPTIONS OF TOENAIL ONYCHOMYCOSIS (A LITERATURE REVIEW)
Authors: Tlish Marina M. , Shavilova Marina E. 
Published: May 2019

Introduction. The importance of investigating the problem of toenail onychomycosis is associated not only with its widespread prevalence among the population and negative effects on the patient life quality, but also with signifi cant diffi culties arising during its therapy. At the moment, a large number of systemic and local antifungal drugs are successfully applied for treating this pathology. Moreover, new physiotherapeutic methods are being developed and introduced into clinical practice. These treatment approaches are based on different action mechanisms, thus demonstrating certain advantages and disadvantages.Discussion. This article sets out to provide a review of antifungal drugs recommended for use in the Russian Federation in patients suffering from onychomycosis of the feet. The results of studies aimed at establishing the clinical effi cacy and application of azole, allylamine, morpholine and ciclopirox derivatives are summarized. Criteria for the selection of these drugs for systemic and local therapy are given. Both Russian and foreign recent publications devoted to physical factors in the treatment of fungal nail infections are analyzed. The action mechanisms, clinical effi cacy, application methods, signifi cant adverse effects of laser and photodynamic methods, as well as ultrasound, magnetic and electric fi elds, are described.Conclusion. Modern approaches to the treatment of toenail onychomycosis are shown to use a large selection of systemic and local antifungal drugs, as well as physiotherapeutic methods for correcting this pathology. All of them have different action mechanisms characterized by particular advantages and disadvantages. To date, there is no universal drug for the treatment of toenail onychomycosis, which would affect all parts of the mycotic process. Following the analysis of recently published literature, it is shown that the use of topical medications and physiotherapy in combination not only signifi cantly reduces the duration of the application of systemic antimycotic drugs, but also expands the etiological indications and their adverse effects. Therefore, such a therapy is established to be the most effective approach to the treatment of toenail onychomycosis at the present stage.
OPTIMIZATION OF ACUTE MYOCARDITIS TREATMENT
Authors: Chepurnenko Svetlana A. , Shavkuta Galina V. , Nasytko Alina D. 
Published: May 2019

Aim. This paper is aimed at investigating the possibility of preventing an adverse outcome of acute viral myocarditis by means of optimal pharmacotherapy without the use of surgical treatment methods.Results. We describe a clinical case of acute viral myocarditis in a 60-year old female patient. According to the conducted echocardioscopy, the dilatation of the heart cavities and the complete insufficiency of the mitral and tricuspid valves were identified. A cumulative effect of the chosen optimal pharmacotherapy, which included an angiotensin converting enzyme inhibitor, a beta-blocker, a mineralocorticoid receptor antagonist and a loopback diuretic with neurohumoral properties taken in optimal doses, allowed congestion signs to be rapidly eliminated, a reverse remodeling of the heart to be achieved and the heart size to be returned normal values. The double blockade of aldosterone receptors using eplerenone and torasemide prevented both the development of fibrosis in the myocardium and the formation of irreversible dilated cardiomyopathy.Conclusion. The application of antiviral and immunomodulatory therapy, along with the maximum possible doses of drugs used to treat chronic heart failure, allowed the patient’s cardiohemodynamic parameters to be returned to normal values. A timely combination therapy should be used to avoid the formation of dilated cardiomyopathy, thus improving the prognosis of the disease.
ANALYSIS OF THE CLINICAL EFFICIENCY OF RESTORATIVE FILLING MATERIALS
Authors: Kolodkina Valentina I. 
Published: May 2019

Aim. To conduct a clinical assessment of short- and long-term surface sealing in patients having a different hygienic status of the oral cavity.Materials and methods. For clinical trials, a group of 250 male and female patients aged 25–45 years old and diagnosed with Black’s class III and V carious lesions was selected. All patients were divided into three groups depending on the state of oral hygiene and the applied methods of aesthetic restoration: control group — defect restoration by Filtek Z-250 microhybrid composite (3M ESPE); comparison group — Filtek Z-250 restoration (3M ESPE) + Easy Glaze (Voco) surface sealing on the day of restoration; and the main group with three subgroups: 2α subgroup — Restavrin restoration + Easy Glaze sealant on the day of treatment; 2β subgroup — Restavrin restoration + Easy Glaze sealant on the day of treatment and re-sealing with a frequency of 1 time per year; 2γ subgroup — Restavrin restoration + Easy Glaze sealant on the day of treatment and re-sealing with a frequency of 1 time per 6 months. The quality of caries cavities was assessed by USPHS criteria, including anatomical shape (AS), marginal pigmentation (MP), marginal adaptation (MA), the presence of secondary caries (SC) and sensitivity (S). The evaluation was conducted on the day of the visit and following 6, 12 and 24 months.Results. A comparison of the clinical evaluation of photocomposite restorations by the Filtek Z-250 (3M ESPE) microhybrid composite in the control group of patients, in comparison group and in the main Restavrin (Technodent) group showed that the Easy Glaze (Voco) surface sealing of the Restavrin composite restorations carried out in the 2α subgroup of the main group onе time on the day of restoration, in the 2β subgroup with re-sealing after 12 months, and in the 2γ subgroup with sealing every 6 months had allowed the maximum number of restorations to be corresponded to the “satisfactory” value according to the AS, MP, MA, SC, S evaluation criteria throughout the entire observation period.Conclusion. The Restavrin (Technodent, Russia) polymeric nanohybrid fi lling material is shown to produce the most effective and durable restorations compared to other materials under study. The applicatiyon of Restavrin followed by the Easy Glaze (Voco) sealing protective system with a frequency dependent on the hygienic status of the oral cavity allows therapeutic methods for dentin caries treatment to be optimized.
ANALYSIS OF THE ANNEXIN V APOPTOSIS MARKER LEVEL AND DENTAL STATUS IN PATIENTS WITH CHRONIC GENERALIZED PERODONTITIS AND BRONCHOECTATIC DISEASE
Authors: Sarkisov Artem K. , Polunina Ekaterina A. , Sarkisov Karen A. 
Published: May 2019

Aim: Our aim was to study and analyze the level of the annexin V apoptosis marker in the oral fluid in patients with generalized periodontitis without general somatic pathology and against the background of bronchiectasis.Materials and methods. 40 patients diagnosed with generalized periodontitis without somatic pathology and 50 patients diagnosed with generalized periodontitis and bronchiectasis were examined. The control group included 40 somatically healthy individuals with intact periodont. Indices characterizing the state of periodontal tissues, such as PMA, PI, Muhlemann, OHI-s were determined for all the examined persons. The level of the annexin V apoptosis marker was determined in the oral fluid by enzyme immunoassay.Results. It was established that the value of the indices of periodontal tissues (PMA, PI, Muhlemann, OHI-s) was statistically signifi cantly higher in the group of patients with generalized periodontitis against the background of bronchiectasis both in comparison with the control group and with the group of patients without general somatic pathology. The level of the annexin V apoptosis marker was also statistically signifi cantly higher in patients with generalized periodontitis against the background of bronchiectasis as compared with the control group and the group of patients without general somatic pathology (p<0.001). According to the correlation analysis, statistically signifi cant relationships of the moderate strength between the level of annexin V and the value of the indices of periodontal tissues were found both in the group of patients without general somatic pathology and in the group of patients with generalized periodontitis against the background of bronchiectasis. At the same time, the strength of these relationships in patients with generalized periodontitis against the background of bronchiectasis was greater as compared to the group of patients without general somatic pathology.Conclusion. The level of the annexin V apoptosis marker in the oral fluid of patients with generalized periodontitis against the background of bronchiectasis is statistically signifi cantly higher (p<0.001) than in patients with generalized periodontitis without general somatic pathology. The results of the correlation analysis indicate the presence of relationships between the level of annexin V and the value of periodontal tissue condition indices (PMA, PI, Muhlemann, OHI-s). Thus, increased apoptosis in generalized periodontitis against the background of bronchiectasis can act as a factor aggravating the damage to periodontal tissues.
EFFECTS OF HYPERBARIC OXYGEN THERAPY ON THE POST-OPERATIVE PERIOD IN PATIENTS WITH A DIFFERENT FUNCTIONAL STATUS
Authors: Stakanov Andrey V. , Golubtsov Vladislav V. , Muronov Alexey E. 
Published: May 2019

Aim. To evaluate the effi cacy of hyperbaric oxygenation (HBO) in patients with a different functional status (FS) after the elimination of acute colonic obstruction (ACO).Materials and methods. A retrospective analysis of 210 medical records of patients who had undergone emergency surgical interventions aimed at ACO elimination was carried out. Based on the value of the direct current potential (DCP), the patients were divided into three groups: 1st (n = 96) with the DCP value from –30 mV and below — FS subcompensation; 2nd (n = 60) with average negative DCP values from –15 to –29.9 mV — FS compensation; 3rd (n = 54) with low negative and positive DCP values from –14.9 mV and higher — FS decompensation. The correlation between patients’ FS and the incidence of postoperative complications was studied, and independent predictors of fatal outcomes were identifi ed. Subsequently, a quantitative analysis of complications and mortality was carried out in each group depending on the use of HBO sessions in the postoperative period, followed by an assessment of their effi cacy.Results. According to the number of perioperative complications and mortality, risk groups in terms of the unfavourable course of the postoperative period were identifi ed: patients with high negative DCP values, for whom the arterial hypotension and acute kidney injury (AKI) could serve as the independent predictors of death; and patients with low negative and positive DCP values, for whom the statistically signifi cant predictors of mortality were shown to be the DCP level, hypotension, AKI and pneumonia. HBO sessions in the postoperative period allow the number of complications in the general population to be reduced: pneumonia by 7%, delirium by 8.8%, AKI by 6.3%, intestinal dysfunction for more than 3 days by 7.3%. In addition, HBO contributed to a 2.9% decrease in suppurative diseases. The analysis of the data on the HBO application in the general population and FS information showed HBO to have a positive effect on the general somatic status of ACO patients. In addition, HBO treatment is shown to decrease the incidence of complications in the early postoperative period. The effi cacy of HBO is found to be higher in the cohort of the most severe patients with decompensated FS, where such complications as delirium, pneumonia and gastrointestinal paresis were decreased by 22.2%, 13% and 18.5%, respectively. As a result, in this group of patients, a signifi cant decrease of 11.1% in 30-day mortality was achieved.Conclusion. The postoperative period depends on the actual FS. The conducted analysis of HBO therapy has convincingly confi rmed its effi cacy in the combined treatment of patients after the elimination of ACO.
RANCANG BANGUN SISTEM INFORMASI OBYEK WISATA BERBASIS WEB MENGGUNAKAN METODE USER CENTERED DESIGN (UCD)
Authors: Yuliani Oni , Prasojo Joko 
Published: May 2019

The development of today's technology has been developing very rapidly and carry a very big change because with the technology information can be obtained quickly, accurately and not limited by time and place. One o f the growing sectors in technology development is in the field of tourism which contributes to distribute information about the attractions more interactive, especially through Internet technology. Yogyakarta has a variety of tourist attractions that are so beautiful, but not many people know the various tourist attractions in the area. Information on tourist places will be known if given a forum to exchange information on the matter in the form of a website. In order to generate tourism website in accordance with the wishes of users, the necessary methods of User Centered Design (UCD) based to the user. It is intended to provide information for tourists so it will be easier to plan excursions according to what they want without hesitation choose the desired attraction. Tourism information system was built using PHP as a programming language and MySQL as a database manager. This information system design using the UCD that engage users by providing input in the form of a questionnaire. This information system contains the profiles sights, means of transportation used and distance traveled. Other facilities that can be enjoyed for information about travel agents who can serve a trip out of town, and the inn (hotel). To implement this system needs the previous test program testing and system testing and then be evaluated. The information system created is a system that is capable of displaying objects on the map and provide information on the map if the object is selected, the user can view more detailed position of an object to be searched. For site owners can perform additional object data without having to perform the construction site from scratch, in this case both the data on a map or information. By making this system the objects displayed on the map always updates that facilitate and assist the user in doing excursions in Yogyakarta.