bluuebunny/crossref_metadata_2025_split huggingface dataset:
New radio continuum study of the large magellanic cloud supernova remnant N49
Authors: Ghavam Maddie , Filipović Miroslav D. , Alsaberi Rami , Barnes Luke , Crawford Evan J. , Haberl Frank , Kavanagh Patrick , Maggi Pierre , Payne Jeffrey , Rowell Gavin , Hidetoshi Sano , Sasaki Manami , Rajabpour Neda , Tothill Nicholas , Urošević Dejan 
Published: November 2024

Abstract
We present new Australia Telescope Compact Array (ATCA) radio observations towards N 49, one of the brightest extragalactic supernova remnants (SNRs) located in the Large Magellanic Cloud (LMC). Our new and archival ATCA radio observations were analysed along with Chandra X-ray data. These observations show a prominent ‘bullet’ shaped feature beyond the southwestern boundary of the SNR. Both X-ray morphology and radio polarisation analysis support a physical connection of this feature to the SNR. The ‘bullet’ feature’s apparent velocity is estimated at

$\sim$

1 300 km s

$^{-1}$

, based on its distance (

$\sim$

10 pc) from the remnant’s geometric centre and estimated age (

$\sim$

7 600 yr). we estimated the radio spectral index,

$\alpha= -0.55 \pm 0.03$

which is typical of middle-age SNRs. Polarisation maps created for N 49 show low to moderate levels of mean fractional polarisation estimated at 7

$\pm$

1% and 10

$\pm$

1% for 5.5 and 9 GHz, respectively. These values are noticeably larger than found in previous studies. Moreover, the mean value for the Faraday rotation of SNR N 49 from combining CABB data is 212

$\pm$

65 rad m

$^{-2}$

and the maximum value of RM is 591

$\pm$

103 rad m

$^{-2}$

.
Troubled water: Tracing the plastic tide on Sierra Leone’s beaches
Authors: Lavelle Stephanie , Preston-Whyte Fiona , Lamin Paul A. , Sankoh Salieu Kabba , Timbo Isha , Maes Thomas 
Published: November 2024

Abstract
This study provides the first investigation into quantities, types, and potential sources of anthropogenic beach litter in Sierra Leone. Beach litter surveys were conducted monthly at four sites over 11 months. A total of 72,901 litter items (1,246 kg dry weight) were categorised. Across all sites, an average of 1,657 items per 100 m (SD = 1,639) and 28.32 kg per 100 m (SD = 37.48) were recorded. Plastics accounted for 70% of the litter by count and 49% by weight. The three most abundant items by count were plastic bottles (25%), plastic caps and lids (13%), and plastic water sachets (12%). By weight, the three most abundant items were plastic bottles (36%), flip-flops (20%), and shoes (9%). Litter amounts decreased from wet to dry season. We provide the following policy recommendations: improving drinking water access and sanitation, waste management, infrastructure and behaviour change.
Effects of the rs174575 single nucleotide polymorphism in FADS2 on levels of long-chain PUFA: a meta-analysis
Authors: Liu Motong , Wu Yanyan , Ni Song , Gong Jiayu , Chen Yifei , He Yuan , Chen Shutong , Yu Haitao , Xie Lin 
Published: November 2024

AbstractThe influence of the SNP rs174575 (C/G) within the fatty acid desaturase 2 gene on the levels of long-chain PUFA was determined through statistical meta-analysis. Six databases were searched to retrieve the relevant literature. Original data were analysed using Stata 17·0, encompassing summary statistics, tests for heterogeneity, assessment of publication bias, subgroup analysis and sensitivity analysis. A total of ten studies were identified and grouped into twelve trials. Our results showed that individuals who carried the minor G allele of rs174575 had significantly higher dihomo-γ-linolenic acid levels (P = 0·005) and lower arachidonic acid levels (P = 0·033) than individuals who were homozygous for the major allele. The subgroup analysis revealed that the G-allele carriers of rs174575 were significantly positively correlated with linoleic acid (P = 0·002) and dihomo-γ-linolenic acid (P < 0·001) and negatively correlated with arachidonic acid (P = 0·004) in the European populations group. This particular SNP showed a potential association with higher concentrations of dihomo-γ-linolenic acid (P = 0·050) and lower concentrations of arachidonic acid (P = 0·030) within the breast milk group. This meta-analysis has been registered in the PROSPERO database (ID: CRD42023470562).
Exploring the impact of caloric restriction on molecular mechanisms of liver damage induced by sucrose intake in the drinking water
Authors: Wiszniewski Morena , Caldareri Lilian , Mori Diego , Martinez Calejman Camila , Cymeryng Cora B. , Repetto Esteban M. 
Published: November 2024

AbstractA positive association has been demonstrated between consumption of sucrose-sweetened beverages and the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD). Since the administration of 30 % sucrose in the drinking water (sucrose-rich diet (SRD)) to rats has proven to be a good model of systemic insulin resistance, the aim of our study was to analyse the effect of caloric restriction applied on SRD-treated rats by switching back to a standard diet, on liver morphology, function and metabolism. Consumption of an SRD causes a metabolic shift towards gluconeogenesis and fatty acid synthesis leading to an increase in TAG levels in plasma and in the liver that were associated with a decrease in insulin sensitivity. Moreover, our results show that animals fed an SRD develop steatohepatitis characterised by the generation of oxidative stress, endoplasmic reticulum (ER) stress, inflammation and apoptosis. Although no histological changes were observed after a 2-week caloric restriction, key pathways associated with the progression of MASLD as inflammation, ER stress and apoptosis were slowed down. Notably, this 2-week intervention also increased liver insulin sensitivity (evaluated by AKT activity in this tissue) and drove the lipid metabolic profile towards oxidation, thus lowering circulating TAG levels. In summary, the present study uncovers underlying mechanisms affected, and their metabolic consequences, during the first stages of the phenotypic reversal of steatohepatitis by switching back to a standard diet after receiving sucrose-sweetened water for several weeks.
Temporal patterns of energy intake and physical activity and cross-sectional associations with body weight status in children and adolescents: results from the Portuguese National Food, Nutrition and Physical Activity Survey 2015–2016
Authors: Cardoso Sofia , Sanches Inês , Correia Daniela , Vilela Sofia 
Published: November 2024

AbstractTemporal energy intake (EI) and physical activity (PA) patterns may be associated with obesity. We aimed to derive and characterise temporal EI and PA patterns, and assess their cross-sectional association with weight status, in 6-to-14-year-old Portuguese participants of the National Food, Nutrition and Physical Activity Survey 2015–2016. We extracted times and EI of all eating occasions from two 1-d food diaries/24-h recalls, while types and times of PA from 4-d PA diaries. We derived EI patterns (n 714) and PA patterns (n 595), using, respectively, a hierarchical and K-means cluster analysis, considering the average proportion of total daily EI (%TEI) and PA intensity (%TPA), within each 2-h interval across the 24-h day. Patterns were labelled based on the 2-h intervals of %TEI/TPA peaks. We assessed the association between patterns and overweight or obesity (BMI z-score ≥ +1 sd) using adjusted logistic regressions (OR (95 % CI)). Three EI patterns emerged: 1 – ‘Early afternoon and early evening’; 2 – ‘Early afternoon and late evening’; and 3 – ‘Late morning, early and mid-afternoon and late evening’. EI Pattern 3 v. Pattern 1 was negatively associated with overweight or obesity (0·49 (0·26, 0·92)). PA Pattern 1 – ‘Late morning, mid-afternoon and early evening’ v. Pattern 2 – ‘Late afternoon’, was not associated with weight status (0·95 (0·65, 1·38)). A daily EI pattern with more and even %TEI peaks at earlier daytime periods, rather than fewer and higher, may be negatively associated with overweight or obesity amongst this population whereas the identified PA patterns might have no relationship.
Prevalence of cardiometabolic diseases in underweight: a nationwide cross-sectional study
Authors: Chen Meng , Shi Shuxiao , Wang Sujing , Huang Yue , Zhou Feng , Zhong Victor W. 
Published: November 2024

AbstractThis study aimed to estimate the nationwide prevalence of cardiometabolic diseases (CMD) among adults with underweight in the US general population. Using data from the National Health and Nutrition Examination Survey (1999–2020), we estimated the age-standardised prevalence of dyslipidemia, hypertension, diabetes, chronic kidney disease, CVD and the presence of zero or at least two CMD. Multivariable Poisson regressions were used to compare CMD prevalence between subgroups, adjusting for age, sex and race/ethnicity. Among the 855 adults with underweight included, the weighted mean age was 40·8 years, with 68·1 % being women and 70·4 % non-Hispanic White. The estimated prevalence rates were 23·4 % for dyslipidemia (95 % CI 19·4 %, 27·5 %), 15·6 % for hypertension (95 % CI 13·3 %, 17·8 %), 2·5 % for diabetes (95 % CI 1·5 %, 3·5 %), 7·9 % for chronic kidney disease (95 % CI 6·9 %, 8·8 %) and 6·1 % for CVD (95 % CI 4·3 %, 7·9 %). The prevalence of having zero and at least two CMD was 50·6 % (95 % CI 44·1 %, 57·0 %) and 12·3 % (95 % CI 8·1 %, 16·4 %), respectively. Non-Hispanic Black adults had significantly higher prevalence of diabetes (adjusted prevalence ratio, 3·35; 95 % CI 1·35, 8·30) compared with non-Hispanic White adults. In conclusion, approximately half of the underweight adults had at least one CMD, and 12·3 % had at least two CMD. Prevention and management of CMD in underweight adults are critical yet neglected public health challenges.
Debating Biblical Translation in Late Elizabethan England
Authors: Spillane Harry 
Published: November 2024

Abstract
This article explores how Protestants defended the co-existence of multiple translations of the Bible into English in Elizabethan England. The matter of biblical plurality is considered through the prism of the debates surrounding bible translation which occurred throughout the 1580s between the Catholic translator of the Bible into English, Gregory Martin (c. 1542–1582), and the English Protestant polemicist William Fulke (1537/8–1589). It is contended that this debate, which has tended to be cast as a storm in a teacup, reveals how Protestants responded, innovatively, to the publication of the Catholic English New Testament. Attention is paid to how Martin attacked the existence of the many different Protestant English bible translations in circulation and, reciprocally, how Fulke defended them. This study of the Martin and Fulke debate thereby unsettles some long-standing assumptions about the combative relationship between different versions of the English Bible and it points, instead, to ways in which contemporaries might have seen the plurality of translations as spiritually and polemically advantageous. Fulke's arguments help us to comprehend how, prior to early seventeenth-century attempts to restrict the existence of multiple English bibles, some Elizabethans responded to, and even defended, the plurality of English bible translations which had come to exist.
Cactodera xinanensis n. sp. (Nematoda: Heteroderinae), a new species of cyst-forming nematode from Southwest China, with a key to the Genus Cactodera
Authors: Ni C.-H. , Li Q.-Y. , Yang Z.-F. , Xu C.-L. , Xie H. 
Published: November 2024

Abstract
The cyst nematodes, subfamily Heteroderinae, are plant pathogens of worldwide economic significance. A new cyst nematode of the genus Cactodera within the Heteroderinae, Cactodera xinanensis n. sp., was isolated from rhizospheres of crops in the Guizhou and Sichuan provinces of southwest China. The new species was characterized by having the cyst with a length/width = 1.3 ± 0.1 (1.1–1.6), a fenestral diameter of 28.1 ± 4.3 (21.3–38.7) μm, vulval denticles present; second-stage juvenile with stylet 21.5 ± 0.5 (20.3–22.6) μm long, tail 59.4 ± 2.0 (55.9–63.8) μm long and hyaline region 28.7 ± 2.7 (25.0–36.3) μm long, lateral field with four incisures; the eggshell with punctations. The new species can be differentiated from other species of Cactodera by a longer tail and hyaline region of second-stage juveniles. Phylogenetic relationships within populations and species of Cactodera are given based on the analysis of the internal transcribed spacer (ITS-rRNA), the large subunit of the nuclear ribosomal RNA (28S-rRNA) D2-D3 region and the partial cytochrome oxidase subunit I (COI) gene sequences here. The ITS-rRNA, 28S-rRNA and COI gene sequences clearly differentiated Cactodera xinanensis n. sp. from other species of Cactodera. A key and a morphological identification characteristic table for the species of Cactodera are included in the study.
Analyses of the essential C82 subunit uncovered some differences in RNA polymerase III transcription between Trypanosoma brucei and Leishmania major
Authors: Cano-Santiago Andrés , Florencio-Martínez Luis E. , Vélez-Ramírez Daniel E. , Romero-Chaveste Adrián J. , Manning-Cela Rebeca G. , Nepomuceno-Mejía Tomás , Martínez-Calvillo Santiago 
Published: November 2024

Abstract
The 17-subunit RNA polymerase III (RNAP III) synthesizes essential untranslated RNAs such as tRNAs and 5S rRNA. In yeast and vertebrates, subunit C82 forms a stable subcomplex with C34 and C31 that is necessary for promoter-specific transcription initiation. Little is known about RNAP III transcription in trypanosomatid parasites. To narrow this knowledge gap, we characterized the C82 subunit in Trypanosoma brucei and Leishmania major. Bioinformatic analyses showed that the 4 distinctive extended winged-helix (eWH) domains and the coiled-coil motif are present in C82 in these microorganisms. Nevertheless, C82 in trypanosomatids presents certain unique traits, including an exclusive loop within the eWH1 domain. We found that C82 localizes to the nucleus and binds to RNAP III-dependent genes in the insect stages of both parasites. Knock-down of C82 by RNA interference significantly reduced the levels of tRNAs and 5S rRNA and led to the death of procyclic forms of T. brucei. Tandem affinity purifications with both parasites allowed the identification of several C82-interacting partners, including C34 and some genus-specific putative regulators of transcription. However, the orthologue of C31 was not found in trypanosomatids. Interestingly, our data suggest a strong association of C82 with TFIIIC subunits in T. brucei, but not in L. major.
Understanding American tegumentary leishmaniasis in urban Montes Claros, Brazil: insights from clinical, immunological and therapeutic investigations
Authors: Lopes Dayse M. S. , Lima Jackeline M. S. , Ribeiro Karine S. M. , Gomes Clarissa F. , Rocha Rebeca M. , Gonçalves Thainara S. , Vieira Thallyta M. , de Carvalho Sílvio F. , Finn M. G. , Venuto Ana Paula , Marques Alexandre F. 
Published: November 2024

Abstract
The challenge of American tegumentary leishmaniasis (ATL) continues in Brazil, presenting a persistent public health issue despite initiatives aimed at public outreach, vector control and health education. To gain a deeper understanding of this disease, a study was conducted in an endemic region located in the northern region of the state of Minas Gerais, Brazil. The study monitored 30 resident patients diagnosed with ATL, using serum samples from 6 healthy individuals as controls. The localized cutaneous form of the disease was found to be predominant, with lesions appearing on various parts of the body and the majority of the affected individuals being male. The study found significantly higher levels of IgG anti-α-Gal antibodies in ATL-infected patients compared to healthy individuals. Treatment of 19 patients with meglumine antimoniate resulted in limited improvement in symptoms for most. Nonetheless, the study found that 12 patients who completed treatment with epithelialization of the lesions showed a significant decrease in IgG anti-α-Gal antibodies, indicating potential applications of this antibody in the diagnosis and monitoring of the disease. The study also identified Leishmania species in 7 analysed patients, revealing 6 cases infected by Leishmania braziliensis and 1 by L. infantum, with a significant difference in the anti-α-Gal responses. The findings of the study emphasize the urgent need for the development of human vaccines and innovative treatment strategies adapted to the diversity of Leishmania species causing cutaneous leishmaniasis and individual patient responses to improve the clinical management of ATL in Brazil and similar endemic regions.
The other mother: ancient and early Byzantine approaches to wet-nursing and mothering
Authors: Constantinou Stavroula , Skouroumouni-Stavrinou Aspasia 
Published: November 2024

AbstractIn premodernity, a time when human milk was the only safe means of infant nutrition, and in societies, such as those of classical antiquity and early Byzantium, where breastfeeding was considered servile work, wet-nursing was both a necessary and widespread occupation. Despite the social demand for the profession, public discourses around wet nurses were mostly negative, while their work was treated with both admiration and scorn. In an attempt to understand ancient and early Byzantine approaches to the wet nurse, this article takes a matricentric perspective. It investigates various discourses (rhetorical, moralist, philosophical, theological, hagiographical, medical and contractual) which establish the wet nurse as an essential part of the institution of motherhood, as a social and moral category whose work, way of life and behaviour are constantly defined, controlled and regulated. These discourses nevertheless tell us much more about the anxieties and preoccupations of the societies that produced them and much less about actual contemporary wet nurses. The choice of an investigation encompassing antiquity up to early Byzantium, an extension rarely seen in existing studies, further illuminates the mechanics and dynamics of the ideologies around the wet nurse, as these are preserved or evolve in time.
The dementia–nature–inclusivity nexus and the needs of people living with dementia
Authors: Stapley Sally , Page Stephen , Wheat Hannah , Owen Steve , Ledingham Katie , Price Stephan , Connell Joanne , Quinn Catherine , Opdebeeck Carol , Victor Christina , Clare Linda 
Published: November 2024

Abstract
Understanding how to improve the physical and cognitive accessibility of visitor economy businesses and organisations wanting to offer nature-based outdoor pursuits for people with dementia is key to supporting their inclusion and agency. The aim of this qualitative study was to understand the experiences, needs and preferences of people with dementia participating in nature-based outdoor pursuits in their leisure time. Semi-structured interviews were conducted with 15 people with dementia and 15 family members and subjected to thematic analysis. Four themes related to inclusion for people with dementia and their family members reflected diversity in individual needs and preferences for engaging with nature-based outdoor pursuits, their own adaptations to maintain access including accommodating risk, how cognitive and physical accessibility can be supported by businesses, and which practical and psychosocial barriers prevent inclusion. Learning from people with dementia and their family members has helped bridge the gap to their inclusion in nature-based outdoor pursuits. Their insights will inform the development of such pursuits by businesses and organisations as well as future work into risk decision-making.
Almost exact recovery in noisy semi-supervised learning
Authors: Avrachenkov Konstantin , Dreveton Maximilien 
Published: November 2024

AbstractGraph-based semi-supervised learning methods combine the graph structure and labeled data to classify unlabeled data. In this work, we study the effect of a noisy oracle on classification. In particular, we derive the maximum a posteriori (MAP) estimator for clustering a degree corrected stochastic block model when a noisy oracle reveals a fraction of the labels. We then propose an algorithm derived from a continuous relaxation of the MAP, and we establish its consistency. Numerical experiments show that our approach achieves promising performance on synthetic and real data sets, even in the case of very noisy labeled data.
Objects, affordances, and material histories in Roman Palestine: a case study on Northern Collar-Neck Lamps and their uses in early Jewish Sources
Authors: Gardner Gregg E. 
Published: November 2024

Abstract
This article seeks to contribute to the growing scholarship on object-focused Roman histories by expanding the conversation to previously overlooked archaeological finds from Roman Palestine. This case study focuses on “Northern Collar-Neck Lamps,” which have been found throughout Roman Galilee and date to the first two centuries CE. I argue that their distinctive high collar, perhaps designed to reduce spillage, also served as an affordance that invited additional modes of interaction, namely placing a supplemental reservoir for oil – such as a pierced eggshell – over the filling hole. Once set up, this would allow for a slow drip of oil to prolong illumination time without human intervention. This usage is suggested from chronologically and geographically proximate sources, namely early rabbinic literature: Hebrew and Aramaic writings from the first centuries that reference physical details and uses of hundreds of objects and could prove helpful for future material histories of the Roman era.
A miniature marvel: left main coronary stenting in a tiny newborn after left coronary artery from the pulmonary artery surgery
Authors: Yükcü Bekir , Paksoy Samet , Ugan Atik Sezen , Gökalp Selman , Haydin Sertaç , Güzeltaş Alper 
Published: November 2024

AbstractAnomalous left coronary artery from the pulmonary artery is a congenital coronary artery anomaly comprising 0.5% of all CHDs. Stenosis in the left coronary artery implanted in the sinus valsalva is one of the complications of surgical repair.Management of coronary stenosis after surgery is very critical and difficult, especially in newborns and infants. Transcatheter procedures can be lifesaving. Herein, the coronary stenting procedure applied to a 3-month-old patient with post-surgical coronary stenosis is presented.