bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating knowledge management with project management for project success
Authors: Yeong Anthony , Lim Thou Tin 
Published: July 2018

This paper aims to study the improvement of project success in organizations by integrating knowledge management strategies with project management practices in a typical project lifecycle. According to the Standish Group’s Chaos Report for 2009, only 32% of all surveyed projects are considered to be successful and are delivered on time, on budget, with the required features and functions. This could be an indication that project management practitioners have not fully acquired and transferred knowledge learned from past projects to ensure a higher success rate for current and future projects. Knowledge management is an emerging discipline and practice in organizations. This paper proposes an integrated model that combines knowledge management with project management to improve project success and thus contribute towards competitiveness and sustainability in organizations.
Encouraging divergent thinking in HRM studies through use of project management case studies
Authors: Twiname Linda Jean , Gibb Jenny 
Published: July 2018

It is important that human resource management (HRM) undergraduate students develop critical thinking around project management decision making as part of their transferable skills development. Such initiatives provide opportunities for students to consider the implications of their decisions in relation to practical settings, that they might better address unexpected HRM demands of the future. We integrate project management into our teaching to progressively build students' skills in HRM. First, students engage in a project management case study and conduct a formal presentation. Second, we extend student awareness of divergent approaches to project management through engagement with excerpts from previous HRM student case studies. Third, the students execute project management of a written case study, under examination conditions. Our approach scaffolds students' higher order thinking and engagement with the divergent nature of the HRM discipline. We provide facilitator and student feedback to illustrate our outcomes. This research is relevant to management educators and, we suggest, is transferable to disciplines other than HRM.
Workforce issues and their impact on projects: study on the Indian IT and ITeS industry
Authors: Jigeesh Nasina 
Published: July 2018

Today’s information technology (IT) industry is facing challenges from different corners because of globalization, technological changes, market and economic fluctuations and dynamic changes in customer requirements. A new stream of jobs has been emerging from time to time in the IT and IT enabled services (ITeS) industry. People management is gaining more concern when compared to technology management. Issues of recruiting right people with right and special skills, motivating them to improve their productivity continuously and retaining potential and productive people are becoming additional challenges to the success of IT projects by enabling the IT industry achieve steady growth and continue the ongoing projects without any interruptions or constraints. The study focuses on the dynamics of human work force of IT projects and analyses the important issues of managing the manpower and their impact on time, cost and quality of the projects. From the analysis of data collected through surveys in some big IT and ITeS companies in India, it was found that the issue of availability of human resources stood as the most significant issue in addition to showing highest impact on quality, cost and time of the IT projects. In contrast, the issue of employees-oriented programs attributed lowest significance and showing least impact on the three success factors of IT projects when compared with remaining ones.
Progress in Powder Coating Technology Using Atomic Layer Deposition
Authors: Adhikari Sangeeta , Selvaraj Seenivasan , Kim Do‐Heyoung 
Published: July 2018

AbstractAtomic layer deposition (ALD) has found versatile applications in energy, environmental, and anthropogenic systems. The self‐terminating surface chemistry characteristic of ALD allows for atomic‐level control over film thickness and has unlocked attractive avenues for the development of novel nanostructured systems. Substantial modifications of standard ALD processes are achieved with the advent of powder coating technology using ALD. The basic principle of ALD is demonstrated along with a focus on the significant parameters governing the process in order to achieve good surface characteristics. The aim of this review is to explore the challenges faced in the development of reactors for powder coatings and solve the problems associated with particle distribution in the reactors. A theoretical briefing on the agglomeration phenomena in particles is provided for a better understanding of the typical particle sizes and their distributions in reactor systems. The gradual improvement in reactor designs, with particular emphasis on the homogeneous distribution of particles, is also discussed. Conclusively, the authors also review the emerging applications where this technology is being explored to overcome surface defects through the control of atomic growth on particles.
Exotic Metamaterials from Noncommutative Theory
Authors: Prudencio Thiago , Belich Humberto 
Published: July 2018

AbstractExotic optical properties in materials are investigated as a consequence of noncommutative geometry (NCG) originated from deformed Heisenberg algebra. The NCG leads to modified eletromagnetism and then changes the constitutive relations that allow the determination of refractive index and impedance of the medium for different materials. Considering different situations where permittivity and permeability are obtained depending on NCG parameters, in dielectric, nonmagnetic, and magnetic cases, exotic conditions associated with metamaterial properties are obtained as the presence of negative index refraction under a generalized susceptibility depending on NCG. These results show that a class of optical metamaterials can be modeled based on NCG depending on noncommutative parameters.
Insights into 2D MXenes for Versatile Biomedical Applications: Current Advances and Challenges Ahead
Authors: Lin Han , Chen Yu , Shi Jianlin 
Published: July 2018

AbstractGreat and interdisciplinary research efforts have been devoted to the biomedical applications of 2D materials because of their unique planar structure and prominent physiochemical properties. Generally, ceramic‐based biomaterials, fabricated by high‐temperature solid‐phase reactions, are preferred as bone scaffolds in hard tissue engineering because of their controllable biocompatibility and satisfactory mechanical property, but their potential biomedical applications in disease theranostics are paid much less attention, mainly due to their lack of related material functionalities for possibly entering and circulating within the vascular system. The emerging 2D MXenes, a family of ultrathin atomic nanosheet materials derived from MAX phase ceramics, are currently booming as novel inorganic nanosystems for biologic and biomedical applications. The metallic conductivity, hydrophilic nature, and other unique physiochemical performances make it possible for the 2D MXenes to meet the strict requirements of biomedicine. This work introduces the very recent progress and novel paradigms of 2D MXenes for state‐of‐the‐art biomedical applications, focusing on the design/synthesis strategies, therapeutic modalities, diagnostic imaging, biosensing, antimicrobial, and biosafety issues. It is highly expected that the elaborately engineered ultrathin MXenes nanosheets will become one of the most attractive biocompatible inorganic nanoplatforms for multiple and extensive biomedical applications to profit the clinical translation of nanomedicine.
Profile of exhaled-breath volatile organic compounds to diagnose pancreatic cancer
Authors: Markar S R , Brodie B , Chin S-T , Romano A , Spalding D , Hanna G B 
Published: July 2018

Abstract

Background
Pancreatic cancer has a very poor prognosis as most patients are diagnosed at an advanced stage when curative treatments are not possible. Breath volatile organic compounds (VOCs) have shown potential as novel biomarkers to detect cancer. The aim of the study was to quantify differences in exhaled breath VOCs of patients with pancreatic cancers compared with cohorts without cancer.

Methods
Patients were recruited to an initial development cohort and a second validation cohort. The cancer group included patients with localized and metastatic cancers, whereas the control group included patients with benign pancreatic disease or normal pancreas. The reference test for comparison was radiological imaging using abdominal CT, ultrasound imaging or endoscopic ultrasonography, confirmed by histopathological examination as appropriate. Breath was collected from the development cohort with steel bags, and from the validation cohort using the ReCIVA™ system. Analysis was performed using gas chromatography–mass spectrometry.

Results
A total of 68 patients were recruited to the development cohort (25 with cancer, 43 no cancer) and 64 to the validation cohort (32 with cancer, 32 no cancer). Of 66 VOCs identified, 12 were significantly different between groups in the development cohort on univariable analysis. Receiver operating characteristic (ROC) curve analysis using significant volatile compounds and the validation cohort produced an area under the curve of 0·736 (sensitivity 81 per cent, specificity 58 per cent) for differentiating cancer from no cancer, and 0·744 (sensitivity 70 per cent, specificity 74 per cent) for differentiating adenocarcinoma from no cancer.

Conclusion
Breath VOCs may distinguish patients with pancreatic cancer from those without cancer.
Return to work after specialized rehabilitation—An explorative longitudinal study in a cohort of severely disabled persons with stroke in seven countries
Authors: Langhammer Birgitta , Sunnerhagen Katharina S. , Sällström Susanne , Becker Frank , Stanghelle Johan K. 
Published: July 2018

AbstractIntroductionStroke may impose disabilities with severe consequences for the individual, with physical, psychological, social, and work‐related consequences. The objective with the current study was to investigate to what extent persons with stroke were able to return to work, to maintain their financial situation, and to describe the follow‐up services and participation in social networks and recreational activities.MethodsThe design was a prospective, descriptive study of specialized stroke rehabilitation in nine rehabilitation centers in seven countries. Semistructured interviews, which focused on the return to work, the financial situation, follow‐up services, the maintenance of recreational activities, and networks, were performed 6 and 12 months post discharge from rehabilitation.ResultsThe working rate before the onset of stroke ranged from 27% to 86%. At 12 months post stroke, the return to work varied from 11% to 43%. Consequently, many reported a reduced financial situation from 10% to 70% at 6 months and from 10% to 80% at 12 months. Access to postrehabilitation follow‐up services varied in the different countries from 24% to 100% at 6 months and from 21% to 100% at 12 months. Physical therapy was the most common follow‐up services reported. Persons with stroke were less active in recreational activities and experienced reduced social networks. Associations between results from the semistructured interviews and related themes in LiSat‐11 were small to moderate. The study shows that education, age, and disability are predictors for return to work. Differences between countries were observed in the extent of unemployment.ConclusionsIn this international multicentre study, return to work after severe stroke and specialized/comprehensive rehabilitation was possible, depending on the extent of the disability, age, and education. Altered financial situation, reduced social networks, and reduced satisfaction with life were common psychosocial situations for these patients.
Evaluation process for an introductory programming course using blended learning in engineering education
Authors: Zampirolli Francisco A. , Goya Denise , Pimentel Edson P. , Kobayashi Guiou 
Published: July 2018

AbstractThe offer of the same course simultaneously for thousands of students, whether in classroom teaching or in distance learning, requires standardization to compare performance between classes and to evaluate the success of the teaching–learning processes. This can be made easier through digital technologies. This study aims to present an Evaluation Process (EP) designed for an Introduction to Programming course (IP) for students of the Bachelor's Degree in Science and Technology (Engineering Education) at the Federal University of ABC. Initially, the course scenario is presented in the classroom modality, Face‐to‐Face (IP‐FF), offered to about 2,000 students every year, identifying the problems, and then, describing the EP designed and applied in Blended Learning classes (IP‐BL). This includes the use of software tools developed for this purpose. The two scenarios (IP‐FF and IP‐BL) are compared using data from all the classes of the previous 9 years.
Comparison of short‐term clinical outcomes of proximal versus nonproximal lesion location in patients treated with primary percutaneous coronary intervention for ST‐elevation myocardial infarction: The PROXIMITI study
Authors: Noaman Samer , Goh Cheng Yee , Vogrin Sara , Brennan Angela L. , Andrianopoulos Nick , Dinh Diem T. , Lefkovits Jeffrey , Reid Christopher M. , Walton Antony , Al‐Mukhtar Omar , Biswas Sinjini , Stub Dion , Duffy Stephen J. , Cox Nicholas , Chan William 
Published: July 2018

AbstractObjectivesThe objective of this study was to investigate the association of proximal and nonproximal location of culprit coronary lesions with clinical outcomes of patients presenting with ST‐elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PCI).BackgroundProximal culprit lesion location in patients presenting with STEMI is associated with increased mortality when compared to distal culprit lesions in the thrombolytic era. The impact of lesion location on clinical outcomes in the era of PCI remains unclear.MethodsWe analyzed 3,283 patients with STEMI who enrolled in the Victorian Cardiac Outcomes Registry. We compared outcomes in those with proximal lesion location versus patients with nonproximal location.ResultsOf 3,283 participants, 1,376 (41.9%) had a proximal lesion location. Patients with proximal lesion location presented with greater rates of cardiogenic shock and out‐of‐hospital cardiac arrest, and left ventricular systolic dysfunction, all P < .01. Procedural success rates were similar (96% vs. 95%, P = .08). Patients with proximal lesion location had higher rates of in‐hospital and 30‐day mortality, major adverse cardiac events (MACE; mortality, myocardial infarction, stent thrombosis, and unplanned revascularization) and major adverse cardiac and cerebrovascular events (MACCE; MACE, and stroke) compared to the nonproximal group, all P < .001. However, on multivariable regression analysis, proximal lesion location was not independently associated with MACE during in‐hospital stay or at 30‐days (OR 1.32, 95% CI 0.95–1.83, P = .09 and OR 1.23, 95% CI 0.92–1.65, P = .15) respectively.ConclusionsPatients with proximal lesion location had greater hemodynamic instability and higher‐risk features; however, proximal lesions per se were not independently associated with worse clinical outcomes compared to nonproximal lesions.
Predicted magnitude of alternate access in the contemporary transcatheter aortic valve replacement era
Authors: Rogers Toby , Gai Jiaxiang , Torguson Rebecca , Okubagzi Petros G. , Shults Christian , Ben‐Dor Itsik , Satler Lowell F. , Waksman Ron 
Published: July 2018

AbstractObjectivesWe aimed to evaluate the true extent of alternate access in a contemporary cohort of transcatheter aortic valve replacement (TAVR) patients.BackgroundAppropriate access selection for TAVR impacts clinical outcomes. Despite device miniaturization, some patients remain ineligible for transfemoral arterial access.MethodsFive hundred seventy‐five consecutive TAVR patients were classified according to iliofemoral artery diameters measured by computed tomography (<5.0 mm, 5.0‐5.4 mm, 5.5‐5.9 mm, or ≥6 mm) and need for alternate access rate was estimated according to commercially available transcatheter heart valve Instructions For Use (IFU).ResultsBased on iliofemoral artery diameters alone, 11.5% of patients were predicted to require alternate access. After patient‐level adjustment for the size of the planned THV and severe tortuosity or severe calcification, 14.9% and 20.8% of patients, respectively were predicted to require alternate access. Overall, 87.8% of patients underwent transfemoral TAVR and 12.3% underwent alternate access. There was no difference in the rate of major vascular complications and life threatening or major bleeding between groups, but transfusion rate was higher in smaller vessel groups.ConclusionsDespite device miniaturization, a substantial minority of contemporary TAVR patients still require alternate access. Most are eligible for newer extrathoracic approaches including transcaval, subclavian, and transcarotid that avoid the morbidity of transthoracic access.
Real clinical experiences of dual versus triple antithrombotic therapy after percutaneous coronary intervention
Authors: Wustrow Isabel , Sarafoff Nikolaus , Haller Bernhard , Rössner Lisa , Sibbing Dirk , Schüpke Stefanie , Ibrahim Tareq , Anetsberger Aida , Schunkert Heribert , Laugwitz Karl‐Ludwig , Kastrati Adnan , Bernlochner Isabell 
Published: July 2018

AbstractObjectivesWe aimed to assess the impact of omitting aspirin on clinical outcomes in a real‐world collective of patients receiving oral anticoagulation (OAC) therapy who were treated with a current‐generation drug‐eluting stent (DES) or an everolimus‐eluting bioresorbable vascular scaffold (BVS).BackgroundLimited data are available regarding the clinical benefit of triple antithrombotic therapy (TAT) with aspirin compared with dual antithrombotic therapy (DAT) without aspirin in patients undergoing percutaneous coronary intervention (PCI) and requiring OAC.MethodsIn total, 237 patients were analyzed. The primary outcome was a composite of major adverse cardiac and cerebrovascular events (MACCE) within 1 year after PCI. Secondary outcomes were the individual components of the primary endpoint, cardiovascular death, and any bleeding according to Bleeding Academic Research Consortium (BARC) or Thrombolysis in Myocardial Infarction (TIMI) criteria.ResultsEighty‐nine patients (37.6%) received DAT, and 148 (62.4%) received TAT. The rate of MACCE was significantly higher in DAT patients than in TAT patients (16 (18%) vs. 11 (7.4%); hazard ratio [HR] 2.73, 95% confidence interval [CI] 1.24–6.03; P = 0.01). The results of the multivariable Cox proportional hazards model including corrections for imbalances in baseline characteristics confirmed a significant independent association between DAT and MACCE (HRadj 3.14, 95% CI 1.31–7.54; P = 0.01). Major bleeding did not differ significantly between treatment groups.ConclusionDAT was associated with a significantly higher rate of MACCE than TAT after DES or BVS implantation. Further studies are required to evaluate the safety and efficacy of dual versus TAT after PCI in clinical practice.
Microcatheter knuckle technique: A novel technique for negotiating the subintimal space during chronic total occlusion recanalization
Authors: Carlino Mauro , Demir Ozan M. , Colombo Antonio , Azzalini Lorenzo 
Published: July 2018

AbstractObjectivesTo establish if novel microcatheter knuckle technique (MKT) is feasible and efficacious in negotiating the subintimal space in difficult lesions during chronic total occlusion (CTO) percutaneous coronary intervention (PCI).BackgroundCTOs remain one of the most challenging lesion subsets in PCI. Guidewire manipulation and advancement of equipment within the subintimal space is sometimes challenging and aggressive manipulation in the subintimal space is feared, because of concern of vessel disruption and perforation. Here we introduce the MKT, for negotiating the subintimal space during challenging CTO PCI.MethodsMKT is performed by creating a wire knuckle with polymer‐jacketed guidewire and positioned in the subintimal space. Subsequently, a tapered‐tip, kink‐resistant microcatheter is advanced towards the knuckled tip of guidewire and the guidewire is simultaneously withdrawn; creating a knuckle‐shaped microcatheter tip. The MKT was considered in CTO PCIs that involved subintimal techniques where resistance to guidewire knuckle advancement was encountered. Procedures were performed between March 2013 and June 2017 at our institution.ResultsDuring the study period, a total of 440 CTO PCIs were performed, from which seven were treated with MKT. MKT was successful in six patients and technical success was achieved in all seven patients. The MKT was successfully performed with both the antegrade and retrograde approach.ConclusionWe present a novel technique for negotiating the subintimal space in CTO PCI for cases where significant resistance is experienced restricting guidewire or material advancement in antegrade or retrograde dissection. The MKT appears to be efficacious complementing the CTO operator's armamentarium.
Reactor Design and Kinetic Study on Adsorption/Desorption of CO and Cl2 for Industrial Phosgene Synthesis
Authors: Bähr Alexander , Moon Gun‐Hee , Diedenhoven Jelka , Kiecherer Johannes , Barth Ekkehard , Tüysüz Harun 
Published: July 2018

AbstractThe aim of this work is the utilization of carbon monoxide (CO) from steel mill gases for the synthesis of phosgene, which can further react with phenol to building blocks for polymers. The effect of impurities like NOx, CO2, and O2 on the activity and stability of the activated‐carbon (AC) catalyst and the follow‐up products should be evaluated. Therefore, new porous carbon catalysts and a new reactor are designed for a systematic kinetic study on the adsorption and desorption behaviors of CO and chlorine (Cl2) on carbon‐based materials to identify AC catalysts with optimum physical properties.
Identification of discrete, intermingled hypocretin neuronal populations
Authors: Iyer Manasi , Essner Rachel A. , Klingenberg Bernhard , Carter Matthew E. 
Published: July 2018

AbstractNeurons in the lateral hypothalamic area that express hypocretin (Hcrt) neuropeptides help regulate many behaviors including wakefulness and reward seeking. These neurons project throughout the brain, including to neural populations that regulate wakefulness, such as the locus coeruleus (LC) and tuberomammilary nucleus (TMN), as well as to populations that regulate reward, such as the nucleus accumbens (NAc) and ventral tegmental area (VTA). To address the roles of Hcrt neurons in seemingly disparate behaviors, it has been proposed that Hcrt neurons can be anatomically subdivided into at least two distinct subpopulations: a “medial group” that projects to the LC and TMN, and a “lateral group” that projects to the NAc and VTA. Here, we use a dual retrograde tracer strategy to test the hypotheses that Hcrt neurons can be classified based on their downstream projections and medial/lateral location within the hypothalamus. We found that individual Hcrt neurons were significantly more likely to project to both the LC and TMN or to both the VTA and NAc than would be predicted by chance. In contrast, we found that Hcrt neurons that projected to the LC or TMN were mostly distinct from Hcrt neurons that projected to the VTA or NAc. Interestingly, these two populations of Hcrt neurons are intermingled within the hypothalamus and cannot be classified into medial or lateral groups. These results suggest that Hcrt neurons can be distinguished based on their downstream projections but are intermingled within the hypothalamus.