bluuebunny/crossref_metadata_2025_split huggingface dataset:
Afterword: Writing Religion and the Genealogy of the Literary Aesthetic
Authors: Connell Philip 
Published: May 2018

AbstractThis afterword takes as its starting‐point the suggestion that the category of the ‘literary’ might be implicated within a historical process of secularisation. This possibility is resisted, at least in respect of its applicability to the influential circle of eighteenth‐century clerical literati associated with Bishop William Warburton, who ranged themselves against the growing influence of the third earl of Shaftesbury and his followers, for reasons that could be construed as at once matters of orthodoxy and questions of taste. In doing so, they helped to form ‘pre‐Romantic’ cultural prejudices while simultaneously defending the interests of the eighteenth‐century Church.
Memory, Community and Textuality in Nonconformist Life‐Writings, 1760‐1810
Authors: Whitehouse Tessa 
Published: May 2018

AbstractThis article asks why memorial writing was so important for religious Dissenters in the eighteenth century, and what the role of women was in the production of nonconformist culture, by investigating the material circumstances of production, preservation and dissemination of life‐writings. It introduces the editorial and commemorative activities of Mercy Doddridge and Jane Attwater, asks how a writer's confessional identity might find its way into the structure and content of her writing and compares processes of composition for printed texts with the compilation and preservation of manuscript records.
‘Serious Books’ and ‘Excellent Meditations’: Recovering Religion in Catherine Talbot's Reading
Authors: Aalders Cynthia 
Published: May 2018

AbstractThis article explores the connections between eighteenth‐century intellectual women and religious reading via a close examination of the letters and diaries of Catherine Talbot (1721‐1770). Talbot was a bluestocking and a devout Anglican, and while her intellectual life has been of considerable interest to scholars, her religious life remains largely unexplored. Yet she often reflected on religion as she encountered it in the books she read. This article restores religion to our understanding of Talbot (and the bluestockings more broadly), illuminates the elusive nature of eighteenth‐century Anglican devotion and contributes to an understanding of women's theological ideas and their circulation.
Introduction: Writing Eighteenth‐Century Religion
Authors: Davies Laura , Salgård Cunha Emma 
Published: May 2018

AbstractThis introduction surveys the methodological approaches, critical categories and vocabularies that have shaped scholarly responses to eighteenth‐century English religious writing. Recognising the significance of recent developments in book history for our understanding of the textual reception of religious texts, we argue for renewed attention to literary production in terms of the agency, identity and experience of both authors and readers. Literary‐critical analysis offers a productive means to this end, revealing the nuances of religious texts and providing powerful new lines of enquiry at the intersection of literary, theological and historical studies of eighteenth‐century religion.
Dissenting from Edward Young's Night Thoughts: Christian Time and Poetic Metre in Anne Steele's Graveyard Poems
Authors: Stenke Katarina 
Published: May 2018

AbstractAlthough the Particular Baptist poet Anne Steele (1718‐1778) is little known today, this article argues that her poems on time and death offer valuable insights into wider religio‐poetical representations of time in the mid‐eighteenth century. Her verse both responds to and departs from the conventions of graveyard poetry as exemplified by Edward Young's Night Thoughts (1742‐6), demonstrating close engagement with this popular subgenre as well as an intelligent critique of its devotional poetics. As such, Steele's writing foregrounds yet also problematises emerging distinctions between writing and religion, and thus argues for new methodologies in religious and literary history.
Pre‐operative haemodynamic monitoring and resuscitation in hip fracture patients: Protocol for a prospective observational study
Authors: Agerskov M. , Sørensen H. , Højlund J. , Secher N. H. , Foss N. B. 
Published: May 2018

BackgroundIn a frail patient group often suffering from dehydration, hip fracture is potentially fatal partly because of the blood loss and thus deteriorated circulation. An important goal for haemodynamic monitoring and resuscitation is early detection of insufficient tissue perfusion. “The peripheral perfusion index” reflects changes in peripheral perfusion and blood volume. We hypothesize that hip fracture patients are hypovolaemic with poor peripheral perfusion and accordingly respond to controlled fluid resuscitation. The peripheral perfusion index might reflect restricted tissue perfusion in spite of stable central haemodynamic variables.MethodsThis prospective observational study assess to what extend hip fracture patients suffer from hypovolaemia and respond to a stroke volume‐guided fluid challenge. The secondary objectives are to evaluate correlation between the non‐invasive peripheral perfusion index and minimally invasive measures of stroke volume, changes in blood volume and near‐infrared spectroscopy determined tissue‐ and cerebral oxygenation and to compare results to prevalence of post‐operative complications including mortality. We will include 50 patients (>65 years) presenting a hip fracture and treated in a multimodal fast‐track regimen when written informed consent is available.DiscussionThis is likely the first study to address pre‐operative haemodynamic monitoring and resuscitation in hip fracture patients where adequate resuscitation is easily missed. We aim to evaluate feasibility of pre‐operative stroke volume‐guided haemodynamic optimization in the context of minimally‐ and non‐invasive monitoring of peripheral perfusion and measure of blood volume.
Hypothalamic Sirt1 protects terminal Schwann cells and neuromuscular junctions from age‐related morphological changes
Authors: Snyder‐Warwick Alison K. , Satoh Akiko , Santosa Katherine B. , Imai Shin‐ichiro , Jablonka‐Shariff Albina 
Published: May 2018

SummaryNeuromuscular decline occurs with aging. The neuromuscular junction (NMJ), the interface between motor nerve and muscle, also undergoes age‐related changes. Aging effects on the NMJ components—motor nerve terminal, acetylcholine receptors (AChRs), and nonmyelinating terminal Schwann cells (tSCs)—have not been comprehensively evaluated. Sirtuins delay mammalian aging and increase longevity. Increased hypothalamic Sirt1 expression results in more youthful physiology, but the relationship between NMJ morphology and hypothalamic Sirt1 was previously unknown. In wild‐type mice, all NMJ components showed age‐associated morphological changes with ~80% of NMJs displaying abnormalities by 17 months of age. Aged mice with brain‐specific Sirt1 overexpression (BRASTO) had more youthful NMJ morphologic features compared to controls with increased tSC numbers, increased NMJ innervation, and increased numbers of normal AChRs. Sympathetic NMJ innervation was increased in BRASTO mice. In contrast, hypothalamic‐specific Sirt1 knockdown led to tSC abnormalities, decreased tSC numbers, and more denervated endplates compared to controls. Our data suggest that hypothalamic Sirt1 functions to protect NMJs in skeletal muscle from age‐related changes via sympathetic innervation.
Implementation and Preliminary Results of an Emergency Department Nontargeted, Opt‐out Hepatitis C Virus Screening Program
Authors: Schechter‐Perkins Elissa M. , Miller Nancy S. , Hall Jon , Hartman Joshua J. , Dorfman David H. , Andry Chris , Linas Benjamin P. 
Published: May 2018

AbstractBackgroundEmergency department (ED) visits provide an opportunity for hepatitis C virus (HCV) screening for patients who otherwise might not be tested. We report on a novel nontargeted, opt‐out HCV screening and linkage‐to‐care (LTC) program implemented in an urban ED.MethodsThis is a descriptive analysis from 3 months (November 2016–January 2017) of a nontargeted, opt‐out ED HCV screening and LTC program among patients at least 13 years old undergoing phlebotomy for clinical purposes. A multipurpose best practice advisory (BPA) alerted providers to the program and generated order labels. For patients who authorized testing, specimens were drawn in the ED for HCV antibody (Ab) and reflex confirmatory RNA tests. Public health navigators attempted to contact RNA‐positive patients and arrange outpatient visits.ResultsHCV Ab tests were performed on 3,808 patients, a 6,950% increase from preprogram. The proportion of HCV Ab test positivity was 13.2% (504/3,808, 95% confidence interval [CI] = 12.2%–14.3%) and of those 97.8% (493/504) had a follow‐up RNA test performed. A total of 292 were confirmed positive for active infection, for an overall RNA positivity rate of 7.7% (95% CI = 6.8%–8.5%). Of those with active infection, 155 (53%) were outside the Centers for Disease Control and Prevention birth cohort for increased risk for HCV including 46 (15.8%, 95% CI = 11.8%–20.4%) who also did not report injection drug use. Linkage attempts were documented on 223 (76.4%) patients and appointments were scheduled for 102 (38% of attempted). Sixty‐six patients attended their LTC visit (22.5% of all RNA‐positive patients, 30% of linkage‐eligible patients).ConclusionsNontargeted opt‐out HCV testing can be successfully implemented in an ED setting. A number of patients diagnosed were outside traditional risk groups. Once diagnosed, an ED population may be difficult to engage in care, but a structured interdisciplinary program can successfully link patients to HCV care.
Sex‐Specific Associations of Risk‐Based Alcohol Drinking Level with Cardiovascular Risk Factors and the 10‐Year Cardiovascular Disease Risk Scores
Authors: Lee Kayoung 
Published: May 2018

BackgroundTo assess sex‐specific associations between risk‐based alcohol drinking levels and the 10‐year cardiovascular disease (CVD) risk scores and cardiovascular (CV) risk factors.MethodsData from 9,995 Koreans (4,249 men, 5,746 women), aged 40 to 79 years who did not have CVD and participated in the 2011 to 2013 Korea National Health and Nutrition Examination Survey, were used to assess risk‐based alcohol drinking levels in the past year (no drinking, drinking at low risk, and drinking at risk) categorized by the National Institute on Alcohol Abuse and Alcoholism, components of the 10‐year CVD risk scores using the Adult Treatment Panel III risk score and the 10‐year hard atherosclerotic CVD risk score, CV risk factors, and confounding factors (age, smoking status, body mass index, educational attainment, income level, and physical activity).ResultsDrinking levels had positive associations with blood pressure and levels of glucose, triglycerides, and high‐density lipoprotein cholesterol (HDL‐C) and inverse associations with levels of low‐density lipoprotein cholesterol and non‐HDL‐C and ratio of total cholesterol (TC) to HDL‐C in men, while higher drinking levels were associated with higher HDL‐C levels and lower ratio of TC to HDL‐C in women after adjusting for confounding factors (p for trend < 0.001). With respect to the 10‐year CVD risk scores, higher drinking levels were associated with lower scores in both sexes (p for trend < 0.001).ConclusionsRisk‐based drinking levels were more likely to have dose‐dependent associations with CV risk factors in men than in women and had inverse relationships with 10‐year CVD risk in both men and women.
Risk for Childhood Internalizing and Externalizing Behavior Problems in the Context of Prenatal Alcohol Exposure: A Meta‐Analysis and Comprehensive Examination of Moderators
Authors: Khoury Jennifer E. , Jamieson Brittany , Milligan Karen 
Published: May 2018

Prenatal alcohol exposure (PAE) is associated with a constellation of physical, neurocognitive, and behavioral abnormalities in offspring. The presence of internalizing (e.g., anxiety, mood disorders) and externalizing (e.g., oppositional defiant and conduct disorders) behavior problems has devastating and often long‐lasting impacts on children, adolescents, and their families. The present meta‐analysis explored the strength of the association between PAE and behavior problems, as well as factors that increase or mitigate risk. The current meta‐analysis included 65 studies comparing children and adolescents with PAE to non‐ or light‐exposed controls and attention‐deficit/hyperactivity disorder (ADHD) samples, on a variety of internalizing and externalizing behavior outcomes. Results indicated that individuals with PAE are at increased risk for internalizing (d = 0.71, medium effect) and externalizing (d = 0.90, large effect) problems compared to control samples. The occurrence of total behavior problems was similar to that seen in ADHD samples. The strength of the association between internalizing and externalizing behavior problems and PAE was significantly moderated by several distinct sample characteristics, such as sample age, socioeconomic status, severity of exposure, and type of behavior problem. These findings further our understanding of the behavior problems experienced by children and adolescents with PAE.
Decomposing Pearson's χ2 test: A linear regression and its departure from linearity
Authors: Zhou Zhengyang , Ku Hung‐Chih , Xing Guan , Xing Chao 
Published: May 2018

AbstractIn case–control genetic association studies, a standard practice is to perform the Cochran‐Armitage (CA) trend test under the assumption of the additive model because of its robustness. We could even identify situations in which it outperformed the analysis model consistent with the underlying inheritance mode. In this article, we analytically reveal the statistical basis that leads to the phenomenon. By elucidating the origin of the CA trend test as a linear regression model, we decompose Pearson's χ2‐test statistic into two components—one is the CA trend test statistic that measures the goodness of fit of the linear regression model, and the other measures the discrepancy between data and the linear regression model. Under this framework, we show that the additive coding scheme, as well as the multiplicative coding scheme, increases the coefficient of determination of the regression model by increasing the spread of data points. We also obtain the conditions under which the CA trend test statistic equals the MAX statistic and Pearson's χ2‐test statistic.
Linguistic Anthropology in 2017: It Could Be Otherwise
Authors: Hoffmann‐Dilloway Erika 
Published: May 2018

ABSTRACTIn this review, I discuss recent works that embody Monica Heller's (2017, 12) assertion that anthropology is about “imagining alternative worlds.” In the first section, “Presence(s), Contact(s), and their Alternatives,” I focus on work that refines our analytical grasp of the semiotic processes underlying past, current, and projected realities, possibilities, and engagements. The second section, “Shifting Political Economies,” deals with publications that specifically explore how political economic conditions are otherwise than was the case when linguistic anthropologists began formulating approaches to the political economies of language in the immediate post–Cold War period. In a third section, “Evidence and/of Imagination,” I examine how linguistic anthropological works published in the period under review have used the terms “imagine/imagined/imaginary” in polyvalent senses when exploring how alternative worlds are conceived and produced, and consider how this nontechnical term can allow scholars to evade or to open up questions of scale and evidence. The final section, “Linguistic Anthropology Could be Otherwise,” takes up work in 2017 that asks how the practice of linguistic anthropology itself could be—and should be—otherwise in terms of our engagements outside the field and the scope of our theoretical and political imaginations. [linguistic anthropology, semiotics, alternatives, imagination, political economies]
Editorial: an expert consensus for the management of chronic hepatitis B in Asian Americans
Authors: Ebel N. H. , Rosenthal P. 
Published: May 2018

Linked ContentThis article is linked to Tong et al and Tong and Pan papers. To view these articles visit https://doi.org/10.1111/apt.14577 and https://doi.org/10.1111/apt.14662.
Editorial: de novo inflammatory bowel disease following bariatric surgery—potential implications for research and clinical practice. Authors’ reply
Authors: Ungaro R. , Colombel J.‐F. 
Published: May 2018

Linked ContentThis article is linked to Ungaro et al and Alukaidey and Heerasing papers. To view these articles visit https://doi.org/10.1111/apt.14569 and https://doi.org/10.1111/apt.14611.
Letter: improvements in mental health after faecal microbiota transplantation—an underexplored treatment‐related benefit? Authors’ reply
Authors: Jalanka J. , Hillamaa A. , Arkkila P. E. , Satokari R. 
Published: May 2018

Linked ContentThis article is linked to Jalanka et al and Mullish papers. To view these articles visit https://doi.org/10.1111/apt.14443 and https://doi.org/10.1111/apt.14626.
Systematic review with meta‐analysis: prevalence, risk factors and costs of aminosalicylate use in Crohn's disease
Authors: Ma C. , Dutton S. J. , Cipriano L. E. , Singh S. , Parker C. E. , Nguyen T. M. , Guizzetti L. , Gregor J. C. , Chande N. , Hindryckx P. , Feagan B. G. , Jairath V. 
Published: May 2018

SummaryBackgroundAminosalicylates are the most frequently prescribed drugs for patients with Crohn's disease (CD), yet evidence to support their efficacy as induction or maintenance therapy is controversial.AimsTo quantify aminosalicylate use in CD clinical trials, identify factors associated with use and estimate direct annual treatment costs of therapy.MethodsMEDLINE, Embase and CENTRAL were searched to April 2017 for placebo‐controlled trials in adults with CD treated with corticosteroids, immunosuppressants or biologics. The proportion of patients co‐prescribed aminosalicylates in placebo arms was pooled using a random‐effects model. Meta‐regression was used to identify factors associated with aminosalicylate use. Annual treatment costs were estimated using the 2016 Ontario Drug Benefit Program.ResultsForty‐two induction and 10 maintenance trials were included. The pooled proportion of patients co‐prescribed aminosalicylates was 44% [95% CI: 39%‐49%] in induction trials and 49% [95% CI: 35%‐64%] in maintenance trials. There was substantial to considerable heterogeneity (I2 = 86.0%, 91.8% for induction and maintenance trials, respectively). In multivariable meta‐regression, aminosalicylate use has decreased over time in induction trials (OR 0.50 [95% CI: 0.34–0.74] per 10‐year increment). While a decline has been seen over time, 35% of CD patients were still using aminosalicylates in contemporary trials from the last 5 years. The estimated annual cost for the lowest price mesalazine (mesalamine) formulation is approximately $32 million for the Canadian CD population.ConclusionsOver one‐third of CD patients entering clinical trials are still co‐prescribed aminosalicylates. A definitive trial is needed to inform the conventional practice of using aminosalicylates as CD maintenance therapy.
Systematic review with meta‐analysis: recurrence of hepatocellular carcinoma following direct‐acting antiviral therapy
Authors: Saraiya N. , Yopp A. C. , Rich N. E. , Odewole M. , Parikh N. D. , Singal A. G. 
Published: May 2018

SummaryBackgroundAlthough studies suggest decreased incident hepatocellular carcinoma (HCC) after direct‐acting antivirals (DAA), data are conflicting regarding HCC recurrence and aggressiveness in patients who have a history of HCC with complete response.AimCharacterize HCC recurrence patterns after DAA therapy.MethodsTwo reviewers searched MEDLINE and SCOPUS from January 2015 to December 2017 and identified studies evaluating HCC recurrence patterns following DAA therapy. A pooled estimate was calculated using the DerSimonian and Laird method for a random effects model. The study was conducted in accordance with PRISMA guidelines.ResultsAmong 24 studies (n = 1820 patients), the proportion of patients with HCC recurrence following DAA therapy ranged from 0% to 59% (pooled estimate 24.4%; 95% CI: 18.4%‐30.4%). Among 11 full text manuscripts, pooled HCC recurrence was 21.9% (95% CI: 16.2%‐28.3%). Factors associated with recurrence included history of prior HCC recurrence and a shorter interval between HCC complete response and DAA initiation. Nine studies comparing DAA‐treated and interferon‐treated or untreated patients found similar recurrence among DAA‐treated patients. Most (77.8%) patients with HCC recurrence were detected at an early tumour stage, of whom 64.7% received curative treatment. Study limitations included heterogeneous cohorts, potential misclassification of HCC absence prior to DAA, ascertainment bias for recurrence, and short durations of follow‐up.ConclusionsCurrent data suggest acceptable HCC recurrence rates after DAA therapy, particularly if DAA therapy is delayed at least 6 months after HCC complete response. However, data characterising HCC recurrence after DAA therapy are of limited quality, highlighting the need for high quality prospective studies.
Review of 20 years of human acute Q fever notifications in Victoria, 1994–2013
Authors: Bond KA , Franklin L , Sutton B , Stevenson MA , Firestone SM 
Published: May 2018

ObjectiveTo describe the epidemiological and clinical features of acute Q fever in Victoria from 1994 to 2013.DesignRetrospective case series and spatiotemporal analyses of human notification data.MethodsRecords for all confirmed cases of Q fever in Victoria notified between 1994 and 2013 were reviewed. Clinical and epidemiological features of the cases were described and spatiotemporal analysis undertaken for all cases potentially acquired within Victoria.ResultsA total of 659 confirmed acute Q fever cases were notified over the study period. Cases decreased at a rate of 4.2% per annum (95% confidence interval (CI): 0.9, 7.4%). Notification rates decreased among abattoir workers and related occupations by 10.9% per annum (95% CI: 6.5, 15.0%), whereas those among dairy farmers rose by 14.9% per annum (95% CI: 4.7, 26.0%). The mean age of cases increased over the study period while the ratio of male to female cases decreased. Spatiotemporal analysis suggested endemic transmission, with 55% of cases associated with abattoirs and related businesses and a further 30% considered to have acquired the infection locally. In addition to abattoir‐associated clusters, important foci for local acquisition included South and East Gippsland, Wodonga and an outbreak centred on a dairy goat farm west of Melbourne.ConclusionsThere has been a reduction in cases of acute Q fever in Victoria over the past 20 years and a changing epidemiology with respect to age, sex and acquisition source. Epidemiological and spatiotemporal analyses suggested a low level of endemic transmission within the state, with multiple foci of increased zoonotic transmission.