bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental and Computational Modeling of the Effects of Voice Therapy Using Tubes
Authors: Horáček J. , Radolf V. , Laukkanen A.-M. 
Published: June 2019

Purpose
Phonations into a tube with the distal end either in the air or submerged in water are used for voice therapy. This study explores the effective mechanisms of these therapy methods.

Method

The study applied a physical model complemented by calculations from a computational model, and the results were compared to those that have been reported for humans. The effects of tube phonation on vocal tract resonances and oral pressure variation were studied. The relationships of transglottic pressure variation in time

P
trans

(
t
) versus glottal area variation in time
GA
(
t
) were constructed.

Results

The physical model revealed that, for the phonation on [u:] vowel through a glass resonance tube ending in the air, the 1st formant frequency (

F
1

) decreased by 67%, from 315 Hz to 105 Hz, thus slightly above the fundamental frequency (

F
0

) that was set to 90–94 Hz
.
For phonation through the tube into water,

F
1

decreased by 91%–92%, reaching 26–28 Hz, and the water bubbling frequency

F
b

≅ 19–24 Hz was just below

F
1

. The relationships of

P
trans

(
t
) versus
GA
(
t
) clearly differentiate vowel phonation from both therapy methods, and show a physical background for voice therapy with tubes. It is shown that comparable results have been measured in humans during tube therapy. For the tube in air,

F
1

descends closer to

F
0

, whereas for the tube in water, the frequency

F
b

occurs close to the acoustic-mechanical resonance of the human vocal tract.

Conclusion

In both therapy methods, part of the airflow energy required for phonation is substituted by the acoustic energy utilizing the 1st acoustic resonance. Thus, less flow energy is needed for vocal fold vibration, which results in improved vocal efficiency. The effect can be stronger in water resistance therapy if the frequency

F
b

approaches the acoustic-mechanical resonance of the vocal tract, while simultaneously

F
0

is voluntarily changed close to

F
1.
Imaging the molecular interstellar medium in a gravitationally lensed star-forming galaxy at z = 5.7
Authors: Apostolovski Yordanka , Aravena Manuel , Anguita Timo , Spilker Justin , Weiß Axel , Béthermin Matthieu , Chapman Scott C. , Chen Chian-Chou , Cunningham Daniel , De Breuck Carlos , Dong Chenxing , Hayward Christopher C. , Hezaveh Yashar , Jarugula Sreevani , Litke Katrina , Ma Jingzhe , Marrone Daniel P. , Narayanan Desika , Reuter Cassie A. , Rotermund Kaja , Vieira Joaquin 
Published: June 2019

Aims. We present and study spatially resolved imaging obtained with the Atacama Large Millimeter/submillimeter Array (ALMA) of multiple 12CO(J = 6 − 5, 8−7, and 9−8) and two H2O(202−111 and 211−202) emission lines and cold dust continuum toward the gravitationally lensed dusty star-forming galaxy SPT 0346-52 at z = 5.656.
Methods. Using a visibility-domain source-plane reconstruction we probe the structure and dynamics of the different components of the interstellar medium (ISM) in this galaxy down to scales of 1 kpc in the source plane.
Results. Measurements of the intrinsic sizes of the different CO emission lines indicate that the higher J transitions trace more compact regions in the galaxy. Similarly, we find smaller dust continuum intrinsic sizes with decreasing wavelength, based on observations at rest frame 130, 300, and 450 μm. The source shows significant velocity structure, and clear asymmetry where an elongated structure is observed in the source plane with significant variations in their reconstructed sizes. This could be attributed to a compact merger or turbulent disk rotation. The differences in velocity structure through the different line tracers, however, hint at the former scenario in agreement with previous [CII] line imaging results. Measurements of the CO line ratios and magnifications yield significant variations as a function of velocity, suggesting that modeling of the ISM using integrated values could be misinterpreted. Modeling of the ISM in SPT 0346-52 based on delensed fluxes indicates a highly dense and warm medium, qualitatively similar to that observed in high-redshift quasar hosts.
Plant Specialized Metabolites in Hazelnut (Corylus avellana) Kernel and Byproducts: An Update on Chemistry, Biological Activity, and Analytical Aspects
Authors: Bottone Alfredo , Cerulli Antonietta , DʼUrso Gilda , Masullo Milena , Montoro Paola , Napolitano Assunta , Piacente Sonia 
Published: June 2019

Abstract
Corylus avellana (hazelnut) is one of the most popular tree nuts on a worldwide basis. The main products of C. avellana are kernels, a nutritious food, with a high content of healthy lipids, contained in a hard shell. In recent years, along with the ongoing research carried out on hazelnut kernels, a growing interest has been addressed to the hazelnut byproducts including hazelnut skin, hazelnut hard shell, and hazelnut green leafy cover as well as hazelnut tree leaf. These byproducts deriving from the roasting, cracking, shelling/hulling, and harvesting processes have been found as a source of “phytochemicals” with biological activity. The aim of this review is to provide a comprehensive and critical update on the chemistry and biological activity of specialized metabolites occurring in hazelnut kernels and byproducts. Phenolics are the most abundant phytochemicals not only in the kernels, but also in other processing byproducts. Attention has been also devoted to taxane derivatives isolated from C. avellana leaves. An overview on the biological activity, mainly antioxidant, antiproliferative, and antimicrobial along with less common biological effects, has been provided, contributing to highlight C. avellana as a source of bioactive phytochemicals with the potential to exert beneficial effects on human health. Finally, analytical techniques for the quali-quantitative analysis of specialized metabolites occurring in the different parts of C. avellana have been reviewed.
Structural Characterization and Anti-complementary Activities of Two Polysaccharides from Houttuynia cordata
Authors: Lu Yan , Zhang Juan-Juan , Huo Jiang-Yan , Chen Dao-Feng 
Published: June 2019

AbstractIn previous studies, crude Houttuynia cordata polysaccharides showed beneficial effects on acute lung injury in vivo, a syndrome in which anti-complementary activities played an important role. Anti-complementary activity-guided fractionation of H. cordata polysaccharides led to the isolation of two highly branched homogeneous polysaccharides, HC-PS1 and HC-PS3, with a molecular weight of 274 530 and 216 384 Da, respectively. The polysaccharides were purified by chromatography on DEAE-cellulose and Superdex columns. Their structural characterization was performed by IR, GC-MS, methylation, NMR, and SEM analysis. Both HC-PS1 and HC-PS3 are composed of eight types of monosaccharides, including rhamnose, arabinose, mannose, glucose, glucuronic acid, galactose, galacturonic acid, and xylose. The main linkages of the sugar residues in HC-PS1 include terminal Rhap, terminal and 1,5-linked Araf; 1,3,6-linked and 1,4,6-linked Manp; terminal, 1,4-linked, 1,3-linked, 1,3,6-linked and 1,4,6-linked and 1,3,4,6-linked Glcp; and terminal, 1,4-linked and 1,6-linked Galp. The main monosaccharide linkages in HC-PS3 are similar to that of HC-PS1, except the additional 1,3,4-linked Manp and the absence of 1,3,6-linked Glcp. HC-PS1 and HC-PS3 were found to inhibit complement activation through both the classical and alternative pathways with 50% inhibition concentrations of 0.272 – 0.318 mg/mL without interfering with the coagulation system. Preliminary mechanism studies indicated that both HC-PS1 and HC-PS3 inhibited the activation of the complement system by interacting with C2, C4, and C5. The results suggest that HC-PS1 and HC-PS3 could be valuable for the treatment of diseases associated with the excessive activation of the complement system.
Association between Salivary Fructosamine, Plasma Glycated Hemoglobin, and Plasma Glucose Levels among Type II Diabetes Mellitus and Nondiabetic Individuals—A Cross-sectional Study
Authors: Kandavel Sadhana , Kumar P.D Madan 
Published: June 2019

Abstract
Objective The study was aimed to determine the association between salivary fructosamine and plasma glycated hemoglobin, plasma fasting and postprandial glucose levels among patients suffering from type II diabetes mellitus and nondiabetic healthy individuals.
Materials and Methods The cross-sectional study was conducted in a hospital setting. A total of 100 participants were included, with 50 participants in each group—group I (patients with type II diabetes mellitus) and group II (nondiabetic healthy individuals). Blood and saliva samples were collected to estimate the levels of the blood and salivary parameters. Depending upon the normality, appropriate tests were used—t-test and Mann–Whitney U test were used for continuous data. Pearson chi-square test and Fisher's exact test were used for discrete data. To test for any positive association between salivary and blood parameters, simple linear regression was carried out.
Results The study results showed that group I had significantly higher levels of salivary fructosamine when compared to group II (p < 0.001). In groups I and II a significant positive association was observed between salivary fructosamine and plasma glycated hemoglobin (group I, r-value 0.893; group II, r-value 0.307).
Conclusion The overall study results showed that salivary fructosamine levels were significantly higher in patients with diabetes when compared to nondiabetic individuals. Also, positive correlation was observed between salivary fructosamine, plasma fasting, plasma postprandial, and plasma glycated hemoglobin among both the groups.
Traditional Medicine and Diabetes Care in Myanmar
Authors: Latt Tint Swe , Aye Than Than , U. Ei Sandar , Win Yin Yin , Wint Khin Thawdar , Khin Ei Thinzar 
Published: June 2019

AbstractAccording to the National Survey of Diabetes and Its Risk Factors conducted in 2014, Myanmar has a high burden of diabetes, as the prevalence of diabetes in adult population was 10.5% and the estimated number of adults with diabetes was 2.5 million. Diabetes care in the country is still far from satisfaction, as more than 50% of people with diabetes were unaware of their diagnosis, and access to the comprehensive diabetes care is generally available in the big cities only. Moreover, most people have to pay the cost of health care out of their own pocket, as the health insurance system and social security system are currently in their rudimentary stage. Because of these gaps in diabetes care and health financing system, a significant number of people resort to the traditional medicine, which is familiar to a significant proportion of the public and also being relatively more accessible with affordable cost. This article assesses the current situation of traditional medicine in diabetes care in Myanmar and attempts to make some suggestions to remedy the drawbacks of traditional medicine. It discusses ways to adopt an integrated approach to strengthen the practice of traditional medicine, in general, in the health care system of the country regarding the diabetes care.
Is Anticoagulant Necessary in Patients with Coronary Artery Ectasia Presenting with Acute Coronary Syndrome? A Systematic Review of Case Reports
Authors: Pranata Raymond , Yonas Emir , Chintya Veresa , Alkatiri Amir Aziz 
Published: June 2019

AbstractCoronary artery ectasia is found in 3 to 8% of patient's undergoing angiography and may sometimes induce acute myocardial infarction. Some articles reported a recurrence of acute coronary syndrome (ACS) in the presence of coronary artery ectasia (CAE). Our study aims to summarize the latest evidence on whether the use of anticoagulant in addition to SAPT/DAPT (single antiplatelet/dual antiplatelet) treating ACS with CAE patients is necessary. Since the trials concerning our objectives were scarce, we pooled case reports/series. We performed a comprehensive search on case reports/series on coronary artery ectasia that presented with acute coronary syndrome published until March 2019. We collected 13 cases from 11 reports. Out of 13 patients, 5 (38.5%) took DAPT only without anticoagulant and 8 (61.5%) took anticoagulant ± DAPT. Three out of five (60%) who took DAPT only, experienced recurrences at 1st and 2nd months' follow-up. The other two (40%) was uneventful at a mean of two months' follow-up. Eight patients who took anticoagulant were uneventful for a mean of 8.4 months. Those who took anticoagulant were at lower risk of experiencing ACS recurrence (p = 0.035). Two of the patients who experienced recurrence became 6 and 12 months free after optimal anticoagulation. The author of this study proposed that anticoagulant must be considered should SAPT/DAPT failed to provide adequate protection to the recurrence of ACS, especially in CAE patients who did not have other obvious stenotic lesions. However, the evidence is weak since this study only pooled case reports/series.
From Ireland to the States
Authors: Filardo-Llamas Laura 
Published: June 2019

AbstractIn this article I start from an understanding of songs as socio-cultural discourses which may also perform a political function. This political function can be reflected in the promotion of particular world-views about given socio-political events and/or in the attempt by the singer to make the audience perform given political actions. To prove this, I will look at the re-contextualisation process undergone by a well-known song by U2: “Sunday, Bloody Sunday” (1983). This song was originally written to respond to the violence of the Northern Irish conflict, but it has been later used to react to other socio-political events. By relying on a cognitive approach to the study of songs, this paper tries to answer two questions: (i) how can we explain the re-contextualisation process undergone by the song and why is it possible? and (ii) how is politics embedded in musical performances?
Translating from/for the margins of empire
Authors: Navarro Aura E. , Poupeney Hart Catherine 
Published: June 2019

Abstract
The third series of the Gaceta de Guatemala (1797–1807) represents a high point of early journalistic production in colonial Spanish America. It benefitted from the presence of a particularly dynamic and cohesive group of young men involved in the development of the paper as a means of improving the social and economic situation of a territory extending from Chiapas to Costa Rica. Against a backdrop of censorship, and undeterred by their marginal position vis-à-vis the European centers of knowledge, they managed to include a surprising number of translations and references to foreign works. In conjunction with Colonial Studies, the Translation Studies perspective adopted in this article highlights how the editors of the Gaceta and their close collaborators, far from being passive consumers, managed to use translation as a tool to engage in, and prepare their readership for, dialogue with the Enlightened elites of the Western world.
A regional assessment of the water embedded in the US electricity system
Authors: Peer Rebecca A M , Grubert Emily , Sanders Kelly T 
Published: June 2019

Abstract
Water consumption from electricity systems can be large, and it varies greatly by region. As electricity systems change, understanding the implications for water demand is important, given differential water availability. This letter presents regional water consumption and consumptive intensities for the United States electric grid by region using a 2014 base year, based on the 26 regions in the Environmental Protection Agency’s Emissions & Generation Resource Integrated Database. Estimates encompass operational (i.e. not embodied in fixed assets) water consumption from fuel extraction through conversion, calculated as the sum of induced water consumption for processes upstream of the point of generation (PoG) and water consumed at the PoG. Absolute water consumption and consumptive intensity is driven by thermal power plant cooling requirements. Regional consumption intensities vary by roughly a factor of 20. This variability is largely attributed to water consumption upstream of the PoG, particularly evaporation from reservoirs associated with hydroelectricity. Solar and wind generation, which are expected to continue to grow rapidly, consume very little water and could drive lower water consumption over time. As the electricity grid continues to change in response to policy, economic, and climatic drivers, understanding potential impacts on local water resources can inform changes.
The contrasting effects of farm size on farm incomes and food production
Authors: Noack Frederik , Larsen Ashley 
Published: June 2019

Abstract
Small-scale farming provides both food and livelihoods for the vast majority of the global poor. Thus, increasing and stabilizing farm incomes and food production in developing countries is fundamental to reducing global poverty. Policies for rural development such as improved access to non-agricultural incomes or land titling may benefit farmers, but they may also lead to farm consolidation with unintended consequences for aggregate food supply. Using a large panel dataset of rural households in Uganda, we parse apart how farm size affects the level and riskiness of agricultural incomes as well as of local food supply. Our findings indicate that while output per unit of land does decline with increasing farm size as suggested by previous literature, agricultural incomes increase with farm size. We show further that while the variance of agricultural incomes declines with increasing farm size, the variance of local food production increases with farm size. These results suggest that farmers benefit from larger farms, earning higher and more stable incomes while consumers suffer from lower and more volatile food supply.
Loss of profit in the hotel industry of the United States due to climate change
Authors: He Pan , Qiu Yueming , Wang Yi David , Cobanoglu Cihan , Ciftci Olena , Liu Zhu 
Published: June 2019

Abstract
Tourism has been identified as a key economic sector vulnerable to climate change, yet direct empirical evidence is still lacking on the economic gain and loss of the tourism industry due to climate change. Here we find that temperature significantly affects the profits of the hotel industry with both spatial and seasonal heterogeneity. By using a rich dataset of the monthly financial records of more than 1700 hotels in 50 US states during 2016–2018 (approximately 3.2% of hotels nationally), we show that a deviation from 18 °C ∼ 20 °C in monthly averaged temperature leads to a decrease in the profit rate. The effect is triggered by fewer customers, less revenue, and higher cost per occupied room partially due to the increased usage of electricity and water. Such an effect can be lasting and is less impactful for higher chain scale hotels. In future GHG emission scenarios, climate change will lead to a loss of profit in most climate zones particularly the southern regions, with higher GHG emissions leading to a more serious effect. This study contributes to the literature on how climate change affects human activities and helps refine the relevant damage function of climate change on tourism in existing climate models.
Detection of fossil fuel emission trends in the presence of natural carbon cycle variability
Authors: Yin Yi , Bowman Kevin , Bloom A Anthony , Worden John 
Published: June 2019

Abstract
Atmospheric CO2 observations have the potential to monitor regional fossil fuel emission (FFCO2) changes to support carbon mitigation efforts such as the Paris Accord, but they must contend with the confounding impacts of the natural carbon cycle. Here, we quantify trend detection time and magnitude in gridded total CO2 fluxes—the sum of FFCO2 and natural carbon fluxes—under an idealized assumption that monthly total CO2 fluxes can be perfectly resolved at a 2°×2° resolution. Using Coupled Model Intercomparison Project 5 (CMIP5) ‘business-as-usual’ emission scenarios to represent FFCO2 and simulated net biome exchange (NBE) to represent natural carbon fluxes, we find that trend detection time for the total CO2 fluxes at such a resolution has a median of 10 years across the globe, with significant spatial variability depending on FFCO2 magnitude and NBE variability. Differences between trends in the total CO2 fluxes and the underlying FFCO2 component highlight the role of natural carbon cycle variability in modulating regional detection of FFCO2 emission trends using CO2 observations alone, particularly in the tropics and subtropics where mega-cities with large populations are developing rapidly. Using CO2 estimates alone at such a spatiotemporal resolution can only quantify fossil fuel trends in a few places—mostly limited to arid regions. For instance, in the Middle East, FFCO2 can explain more than 75% of the total CO2 trends in ∼70% of the grids, but only ∼20% of grids in China can meet such criteria. Only a third of the 25 megacities we analyze here show total CO2 trends that are primarily explained (>75%) by FFCO2. Our analysis provides a theoretical baseline at a global scale for the design of regional FFCO2 monitoring networks and underscores the importance of estimating biospheric interannual variability to improve the accuracy of FFCO2 trend monitoring. We envision that this can be achieved with a fully integrated carbon cycle assimilation system with explicit constraints on FFCO2 and NBE, respectively.
EXO OLO TASK: The Development of Higher Order Thinking Skills through Learning Activities Management in Geography Learning
Authors: Nofrion  , Suasti Y , Khairani  , Rahmanelli  , Wijayanto B , Novio R , Surtani  
Published: June 2019

Abstract
This article was written to explain the suitability between the scores of advance learning activities achieved by students with the "gain score" from the results of the pre-test and post-test of HOTS questions. Advance learning activities include, 1)analyzing, 2)communicating/dialogue, 3)discussing/collaborating. Whereas HOTS question is a question that testing students’ creativity and strategy in solving problems and is at the level of C4 (analyzing), C5 (evaluating) and C6 (Creating). EXO OLO TASK Learning Model was applied in this quasi-experimental research for four meetings in class X IS 1. The model was practiced by a model teacher and learning activity data was collected by six observers. The suitability was obtained by percentage analysis and strengthened by correlation test with the help of SPSS version 20. The results showed that, 1) during learning, all students showed consistent basic learning activities; 2) most students had a "gain score" in the medium category. While 24.13% of students were able to reach high categories and only 6.89% of students with low gain scores, 3) 65.51% of students had scores of learning activities that match the "gain score" and 34, 48% did not. The implementation of this model has only been applied in one class and one school so that it is necessary to implement it in broader classes and schools.