bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMPARISON OF MUTANT P53 PROTEIN EXPRESSION IN PTERYGIUM GROUP WITH AND WITHOUT TRIAMCINOLONE ACETONITED INJECTION
Authors: Erna Riani 
Published: March 2019

Background: Mutant p53 protein is produced by mutant p53 gene, this protein takes part in tissue hyperplasia process in pterygium. Triamcinolone acetonide in often use to reduce reccurency. Besides decreasing the inflamation triamcinolone acetonide is assumed to be able to repair the function of p53 gene. Thus, it reactivates cell apoptosis system and prevent the tissue hyperplasia process in pterygium.To compare Mutant p53 Protein Expression in Pterygium Group With and Without Triamcinolone Acetonide InjectionMethods: This research is a randomized clinical trial study consists of 31 subject who suffered primary pterygium. All subject divided into 2 grup with and without triamcinolone acetonide injection. After excision the pterygium and the tissue were examined through histopatology and immunohistochemical with Hematcoycline Eosin and reagent Clone DO7 staining to see the mutant p53 protein expression.Results: Mutant p53 protein expression in triamcinolone acetonite injected group is 0% and non triamcinolone acetonite injected group is 33,33%Conclusion: Mutant p53 protein expression in triamconolone acetonite injected group is lower than non injected grou.
Keywords: Mutant p53 protein, primary pterygium, triamcinolone acetonide immunohistochemicial
ANALISIS FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PEMANFAATAN PELAYANAN KESEHATAN PADA PESERTA JAMINAN KESEHATAN NASIONAL DI WILAYAH KERJA PUSKESMAS PAYAKABUNG, KABUPATEN OGAN ILIR
Authors: Irawan Bambang , Ainy Asmaripa 
Published: March 2019

Latar Belakang: Puskesmas menyediakan layanan kesehatan bagi peserta Jaminan Kesehatan Nasional (JKN). Berdasarkan data dari dinas kesehatan kabupaten Ogan Ilir tahun 2017, kunjungan pasien rawat jalan terendah terjadi di Puskesmas Payakabung sebesar 650 pasien. Tujuan penelitian ini adalah untuk menganalisis faktor-faktor yang berhubungan dengan pemanfaatan pelayanan kesehatan pada peserta JKN di wilayah kerja Puskesmas Payakabung.Metode: Jenis penelitian ini adalah cross sectional menggunakan teknik pengambilan sampel simple random sampling dengan jumlah sampel sebanyak 112 orang.Hasil Penelitian: Hasil penelitian menunjukkan bahwa hanya sebesar 43,8% responden yang memanfaatkan layanan kesehatan. Paling banyak responden menunjukkan karakteristik sebagai berikut: usia≤46 tahun (60,7%), perempuan (59,8%), pendidikan rendah (76,8%), bekerja (66,1%), memiliki persepsi yang baik mengenai sikap petugas (61,6%), memiliki persepsi yang baik mengenai JKN (55,4%), jarak antara rumah dan puskesmas dekat (67,9%) and memiliki persepsi positif mengenai sakit (58,9%). Ada hubungan signifikan antara variable usia (p-value < 0,0001), jenis kelamin (p-value = 0,016), persepsi mengenai JKN (p-value = 0,039), aksesibilitas layanan (p-value < 0,0001) dengan pemanfaatan layanan kesehatan bagi peserta JKN di wilayah kerja Puskesmas Payakabung.Kesimpulan: Berdasarkan uji statistik, terdapat empat variabel yang berhubungan secara signifikan dengan pemanfaatan layanan kesehatan (usia, jenis kelamin, persepsi mengenai JKN, aksesibilitas layanan).Disarankan agar pemahaman mengenai program JKN bagi masyarakat sangat diperlukan untuk efektifitas layanan kesehatan di puskesmas.
HUBUNGAN PEMBERIAN ASI EKSKLUSIF DALAM PRESPEKTIF SOSIAL BUDAYA DI KOTA PALEMBANG
Authors: Fajar Nur Alam , Purnama Dadang Hikmah , Destriatania Suci , Ningsih Nurna 
Published: March 2019

Latar Belakang: Pemberian ASI eksklusif secara nasional pada tahun 2010-2012 hanya 33,6-35% yang dipengaruhi oleh interaksi dari berbagai faktor sosial, demografi, biologi, pre dan postnatal, dan psikologi. Meskipun berbagai studi menunjukkan bahwa Pemberian ASI Eksklusif dapat memberikan manfaat kesehatan pada bayi maupun ibunya, namun hasilnya belum sesuai dengan yang harapkan. Kemajuan modernisasi merupakan salah satu penyebab terjadinya perubahan sosial, budaya maupun ekonomi, sehingga dampaknya berpengaruh terhadap menurunnya dukungan pada ibu menyusui. Data Survei Demografi Kesehatan Indonesia Tahun 2007 menunjukkan bahwa pemberian ASI eksklusif mengalami penurun sebesar 30,2% dan peningkatan pemberian susu formula sebesar 11% pada tahun 2013. Penelitian ini bertujuan untuk menjelaskan hubungan perilaku Pemberian ASI Eksklusif berdasarkan perspektif sosial budaya di Kota Palembang. Metode: Penelitian ini menggunakan analisis cross sectional yang bertujuan menjelaskan hubungan perilaku Pemberian ASI Eksklusif berdasarkan perspektif sosial budaya di Kota Palembang. Hasil Penelitian: Sampel penelitian ini berjumlah 220 responden. Hasil analisis tersebut menunjukkan bahwa jumlah anak (p-value=0,003) dukungan ibu atau mertua (p-value=0,001) memiliki hubungan signifikan dengan pemberian ASI Eksklusif pada bayi, sedangkan jenis pekerjaan, pendidikan istri, pendidikan suami, komposisi keluarga, pengetahuan ASI eksklusif dan sikap ibu tidak memiliki hubungan yang signifikan (p>0,005) terhadap pemberian ASI eksklusif pada bayi.Kesimpulan: Hasil analisis hubungan menunjukkan responden yang memiliki jumlah anak ≤ 2 orang, dukungan suami dan dukungan mertua, tidak mencari informasi berhubungan secara signifikan terhadap pemberian ASI eksklusif pada bayi. Sedangkan ibu yang berhubungan,tingkat pengetahuan ibu, jenis pekerjaan ibu dan sikap ibu tidak menunjukkan adanya hubungan terhadap pemberian ASI eksklusif pada bayi.
Mantra Pengobatan Anak Rewel Subsuku Dayak Desa Ensaid Panjang Kecamatan Kelam Permai Kabupaten Sintang
Authors: Sudarto Sudarto , Adpriyadi Adpriyadi 
Published: March 2019

Penelitian ini bertujuan untuk mendeskripsikan jenis gaya bahasa, makna kata, dan lingkungan pembacaan mantra yang terdapat dalam mantra pengobatan anak rewel pada masyarakat Dayak Desa Ensaid Panjang Kecamatan Kelam Permai Kabupaten Sintang. Metode yang digunakan dalam penelitian ini adalah deskriptif, dengan bentuk penelitian kualitatif dan pendekatan yang digunakan dalam penelitian ini adalah pendekatan struktural semiotik. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah teknik perekaman, pengamatan langsung, dan teknik wawancara bebas terarah. Hasil penelitian menunjukkan bahwa gaya bahasa yang terdapat dalam mantra pengobatan anak rewel masyarakat Dayak Desa Ensaid Panjang meliputi: (1) gaya bahasa yang terdapat dalam mantra pengobatan masyarakat Dayak Desa Ensaid Panjang meliputi: (a) gaya bahsa pengulangan Aleterasi (b) gaya bahasa pengulangan kiasmus. (2) kata-kata yang terdapat dalam mantra berisikan permohonan agar penyakit yang diderita oleh seseorang dapat tersembuhkan (3) lingkungan pembacaan mantra pengobatan masyarakat Dayak Desa Ensaid Panjang tidak memiliki pantangan-pantangan, dalam melakukan pengobatan boleh kapan saja, hanya menyan yang harus ada dan yang lain boleh tidak ada.
Salt Stress Triggered Changes in Osmoregulation and Antioxidants in Herbaceous Perennial Inula Plants (Asteraceae)
Authors: Pehlivan Necla , Saruhan Güler Neslihan 
Published: March 2019

Global demand to cure ailments is a growing
need. Inula genus extensively holds hundreds of species in warmer regions of
Europe and Asia. It is being well-known for its phytochemical and
pharmacological applications in industry thanks to its anti-inflammatory and
antimicrobial interests. However, growth and production of Inula in the
cutting-edge industry is commonly influenced by salt stress except for the
halophyte species such as the Inula
crithmoides. Salt tolerance level by means of changes in osmoregulation and
antioxidant systems in an herbaceous perennial Inula plant has been
biochemically evaluated here. Both salt stress treatments caused photosynthetic
pigments’ degradation, increase in the leaf levels of osmolytes, and induction
of oxidative stress indicated by the malondialdehyde (MDA). Higher hydrogen
peroxide (H2O2) amount was recorded in high
salt concentration than low salt. High salinity caused an increase in ascorbate
(ASC) and glutathione (GSH) contents besides target enzymes of Inula leaves.
NaCl tolerance of Inula also was found comprehensible through the higher
concentrations of proline and to a lesser extent, total soluble sugar. Salt
tolerance mechanisms of this rich bioresourse needs to be further studied in
detail for herbal medicines in pharma sector.
Enhancing the Behavior of One-Way Reinforced Concrete Slabs by Using Laced Reinforcement
Authors: Hallawi Ali Faiq , Al-Ahmed Ali Hussein Ali 
Published: March 2019

This paper studies experimentally the behavior of laced reinforced concrete one-way slabs under monotonic load. The experimental program included testing three simply supported one-way slabs of dimensions (1500 mm length, 600 mm width, and thickness 130mm. One of these slabs was the control specimen which was designed without lacing reinforcement steel and the other two specimens designed were with two variable lacing reinforcement ratio (0.27% and 0.52%). All specimens were cast with normal of 22 MPa compressive strength. Specimens were tested under two equal line loads applied at the third parts of the slab (monotonic load) gradually applying up to failure. The specimens showed an enhanced in ultimate load capacity up to 40% as a result of increasing the lacing steel ratio to 0.52 %. Also, decreasing in deflection at service and at ultimate load levels by 42% and %57 respectively. In addition, the results showed that specimen with lacing reinforcement are more ductility than specimen without lacing reinforcement so using of lacing steel reinforcement leads to significant improvements in ductility index which reached to about 49% with increasing the lacing steel ratio to (0.52%).
Where Do Semantic Illiteracy and Stylistic Tolerance Lead? (Essay Notes)
Authors: Shatalova O. V. 
Published: March 2019

The article attempts to establish the correlative relationship between the understanding of the lexical meaning and the stylistic qualification of a word with the peculiarities of the thinking and worldview of a student. The use of official business cliches is defined as a factor of the development and socio-psychological realization of an individual.
Problem Definition in the Text of the Unified State Exam in the Russian Language: Conceptual Approach
Authors: Gavrilov V. V. 
Published: March 2019

The author attempts to present the method of identifying the problem in the text of the Unified State Exam in the Russian language using conceptual analysis, which will make the work in this direction less formalized and develop the textual competence of students. The author describes the conceptual analysis and its main principles and offers an analysis of a specific text using the proposed methodology. Having acquired the skill of conceptual analysis, pupils will be able to define the problem of the text consciously and to formulate their opinion and assessment of the problem under consideration, as well as to participate in discussions, argue their own conclusions, and give relevant examples.
Lexical-semantic Field «Happiness» in the Composition-speech Structure of the Miniature of the Same Name by V.P. Astafiev (For the 95th Birth Anniversary)
Authors: Gejmbuh E. Yu. 
Published: March 2019

The article is devoted to one of the aspects of the compositional speech structure of the miniature «Happiness» – the ratio of two semantic fields – happiness and unhappiness – and their role in creating an image of the world. The author comes to the conclusion that the center and periphery of the field are formed around the core (happiness – sleep). Joy, beauty, and intimacy (the center) have been exclusively in the field of «happiness»; however light, breath, love and music appear ambivalent, since they can belong to both opposing worlds (the periphery).
The Use of the Letter ё: History and Modern Writing
Authors: Kaverina V. V. 
Published: March 2019

The article discusses the controversy regarding the date of the first use of the letter ё in a printed form and argues that the first printed use of this letter refers to 1797. Much attention is paid to the problem of introducing the mandatory use of the letter ё in modern Russian writing. The author comes to the conclusion that it is necessary to use e in proper nouns, geographical names and words with unclear pronunciation.
Estudio acerca del conocimiento, actitudes y prácticas del cribado de cáncer de piel, mama y cérvix en una muestra de mujeres en Concordia, Argentina
Authors: Pezzotto Stella M , Nieto Claudia Silvia , Baroni María Antonella , Iwanow Pablo , Dagatti María S 
Published: March 2019

Introduction. The aim of this study was to describe the knowledge, practices and attitudes regarding the screening of skin cancer, compared to the breast and cervix cancer. Methods. An observational, cross-sectional study using structured questionnaires was carried out among women in the city of Concordia, Entre Ríos. The sample consisted of 90 mothers or tutors from low (G1, n=32), middle (G2, n=29) and high (G3, n=29) socioeconomic status elementary schools students. Results. Mean age were 37,9±6,6, 38,0±6,9 and 43,1±5,6 years, respectively. The annual skin exam has been performed by dermatologist in 30.0% (G1), 30.8% (G2) and 51.7% (G3) of these women. The annual gynecological exam has been done by 46.4% (G1), 60.7% (G2) and 86.2% (G3). The existence of the skin cancer prevention campaign was known in 35,7%, 16% and 10,7% in G1, G2 and G3 respectively, but only 3,7% of G2, 3,7% of G3 and no women in G1 had ever participated in a campaign. Major conclusion. These data indicate the need to achieve effective strategies that allow improving the adherence of women to prevention campaigns, especially those for skin cancer prevention, where there is less participation when compared with breast and cervical cancer screening.
Effect of Social Media Marketing on The Conversion Rate of Deposit Money Banks in Nigeria
Authors: Enyioko Newman C , Okwandu Gabriel A 
Published: March 2019

The study examined the effect of social media marketing on the conversion rate of deposit money banks in Nigeria. Blog, Facebook, Twitter, and LinkedIn were used as the dimensions of social media marketing. The study revealed a gap from the literature that social media marketing and organizational efficiency of banks in Nigeria has not been extebsively studied in Nigeria. The study used the conversion rate as a dependent variable. The study adopted descriptive and inferential statistical tools to analyze the data and test the hypotheses. A questionnaire was used to elicit information from the respondents. The population of the study consisted of all the 22 banks approved by CBN. The study sampled 159 respondents from 22 banks in Nigeria and validly used 133 respondents representing 83.65% response rate for data analysis. The study found that banks use a blog, Facebook, Twitter, and LinkedIn to conduct their marketing activities for brand promotion and persuasion of customers to patronize them. The study revealed that Blog has a positive but insignificant effect on conversion rate. The study discovered that Facebook has a positive and significant effect on conversion rate. The study revealed that Twitter has a positive and significant effect on conversion rate. The study found that LinkedIn has a positive and insignificant effect on conversion rate. The study concludes that as banks use blogs, Facebook, Twitter, and LinkedIn to create awareness about their products and services on the internet. The study recommends that bank managers should use Blog, Facebook, Twitter, and LinkedIn by encouraging all the bank staff to participate in social media marketing which in turn covers more ground for the enhancement of conversion rate leading to the conversion rate of banks.
Оцінка розвитку посівів сорго зернового за фенологічними спостереженнями
Authors: Свиридова Л. А. , Рожков А. О. 
Published: March 2019

Висвітлено результати чотирирічних досліджень щодо впливу технологічних чинників: способів сівби та норм висіву на час проходження окремих фаз розвитку рослин сорго зернового. У дослідах доведено вплив цих чинників на варіабельність тривалості проходження досліджуваних фаз росту і розвитку рослин.
Із послабленням ценотичної напруги у посівах за рахунок застосування широкорядного способу сівби з міжряддями 45 см і норм висіву насіння 120 і 160 тис. шт./га відзначено прискорене проходження посівами сорго зернового фази трубкування. Разом із тим зменшення конкурентної боротьби в посівах рослин за оптимізації способу сівби та зменшення норми висіву, навпаки, приводило до «розтягування» фази кущіння та міжфазного періоду формування-наливання зерна, що сприяло повнішому використанню агроресурсу та формуванню вищої врожайності зерна рослин. Відмічені закономірності проявлялися в усі роки досліджень.
The results of the four-year research concerning the influence of technological factors dealing with the: methods of sowing and seeding standards during the individual certain stages of the grain sorghum plants development are presented. The experiments proved the influence of these factors on the variability of the duration of the studied phases concerning growth and development of plants. When the coenotic stress in the crops grows weak due to the use of a broad-row sowing method with intermediate rows of 45 cm and seeding standards of 120 and 160 thousand pcs./ha, the accelerated tubing phase passage of grain sorghum crop was noted. At the same time, when the competition in plant crops to optimize the sowing method and reduce the seed rate became low on the contrary, it caused the «stretching» of the busing phase and the interphasal period of grain forming and ripening, which contributed to a more complete use of agrarian resources and the formation of higher crop yields. The marked patterns were manifested during all years of research.
Передпосівна обробка насіння як елемент управління продуктивним потенціалом пшениці озимої
Authors: Маренич М. М. 
Published: March 2019

Наведені результати досліджень використання протруйників та гуматів для передпосівної обробки насіння. Встановлено, що додавання гуматів у суміші з протруйниками закономірно підвищувало показники польової схожості та кількості вузлових коренів порівняно з контролем. Середньорічні показники свідчать про закономірний вплив застосування стимуляторів на скорочення періоду «сівба–сходи», проте за несприятливих умов проростання застосування стимуляторів може відігравати дуже важливу роль для отримання дружних сходів.
У випадку застосування гуматів польова схожість насіння зросла на 11–13 %. За несприятливих умов, що склалися на період проростання дія факторів посилювалася і збільшувався вплив таких взаємодій як «попередники–сорт» та «сорт–варіант обробки насіння».
Утворення вузлових коренів також істотно залежало від варіанту обробки насіння. Найкращим показником характеризувався варіант досліду, де використовувався «1R Seed treatment», що в подальшому значною мірою вплинуло на формування врожайності.
У всіх проведених дослідах відзначали позитивний вплив застосування для обробки насіння стимуляторів «Гуміфілд» та «1R Seed treatment» як у сумішах з протруйниками, так і у варіантах, де вони використовувалися окремо.
The results of studies on the use of disinfectants and humates for presowing seed treatment are presented. It was found that the introduction of humates in a mixture with preservatives naturally increased the field germination and the number of nodal roots compared to the control. Average annual indices testify to the natural effect of the use of stimulants on the reduction of the period of «sowing–shoots», but under adverse conditions of germination the use of stimulants can play a very important role in obtaining amicable shoots.
In the case of application of humates, the field germination of seeds increased by 11–13 %. Under unfavorable conditions prevailing during the germination period, the effect of the factors increased and the influence of such interactions as «precursors–grade» and «variety–variant of seed treatment» increased.
The formation of nodal roots also significantly depended on the variant of seed treatment. The best indicator was a variant of the experiment, where «1R Seed treatment» was used, which subsequently significantly influenced the formation of yields.
In all the experiments conducted, the positive effect of the use of stimulants «Humifield» and «1R Seed treatment» for seed treatment, both in mixtures with disinfectants, and in cases where they were used separately, was noted.
Вплив трансплантації культур клітин на стан острівкового апарату підшлункової залози та рівень глюкози у крові за експериментального цукрового діабету у тварин
Authors: Ковпак В. В. , Ковпак О. С. 
Published: March 2019

У статті описано вплив різних видів культур клітин (підшлункової залози, кісткового мозку та жирової тканини) на перебіг експериментального цукрового діабету у щурів. Досліджено, що оптимальним методом введення клітинного матеріалу, є трансплантація його під капсулу підшлункової залози. Під час дослідження стану острівкового апарату за введення різних видів культур клітин на фоні цукрового діабету виявили, що всі вони володіють позитивним терапевтичним ефектом під час лікування вказаної патології. Отримані дані підтверджуються збільшенням загального об’єму острівкової тканини у тварин-реципієнтів (у порівнянні з контрольною групою), що у свою чергу призводить до зниження рівня глюкози у сироватці крові.
The article describes the influence of various cell cultures (pancreas, bone marrow, adipose tissue) on the clinical course of experimental pancreatic diabetes of rats. It is found out that the optimal method of cell material injection is its transplantation under the pancreatic capsule. The study of islet cell condition under injecting various cell cultures in the setting of pancreatic diabetes showed that all of them produce a positive therapeutic effect in the treatment of the this pathology. The obtained data is testified by the growth of a general volume of islet tissue of recipient animals (compared to a control set); this in its turn results in the decrease of blood serum glucose level.
Impact of Iron Status on Thyroid Function: A Community Based Cross-Sectional Study in Eastern Nepal
Authors: Thapa Saroj , Lamsal Madhab , Sah Sanjay Kumar , Chaudhari Rajendra Kumar , Gelal Basanta , Kunwar Saroj , Baral Nirmal 
Published: March 2019

Background: Iron deficiency is the most common nutritional deficiency in the world. The relation between thyroid hormones and iron status is bidirectional. The aim of this study was to assess iron nutrition status and evaluate its relationship with thyroid hormone profile among children of Eastern Nepal.
Methods: A community based cross-sectional study was conducted in eastern Nepal. A total of 200 school children aged 6-12 years were recruited after taking informed consent from their guardians. Blood samples were collected and assayed for free thyroid hormones (fT3 and fT4), thyroid stimulating hormone (TSH), serum iron, total iron binding capacity (TIBC) concentration and percentage transferrin saturation was calculated.
Results: The mean serum iron and TIBC was 74.04 µg/dl and 389.38 µg/dl respectively. The median transferring saturation was 19.21%. The overall prevalence of iron deficiency (Transferrin saturation < 16%) was 34% (n=68). The mean concentration of fT3 and fT4 was 2.87 pg/ml and 1.21 ng/dl respectively, while the median TSH concentration was 3.03 mIU/L. Median TSH concentration in iron deficient group (3.11 µg/dl) and iron sufficient group (2.91 µg/dl) was not significantly different. Among iron deficient children 5.9% had subclinical hypothyroidism (n=4). Iron status indicators were not significantly correlated with thyroid profile parameters in the study population.
Conclusions: The prevalence of iron deficiency is high and iron deficiency does not significantly alter the thyroid hormone profile in the study region.