bluuebunny/crossref_metadata_2025_split huggingface dataset:
Iranian firms in biopharmaceutical value chain: where to go now?
Authors: Afshari-Mofrad Masoud , Salim Ali 
Published: June 2019

Purpose
Motivated by the huge potential of biosimilars in the near future and rapid growth of Iranian biosimilar producing firms in recent two decades, this paper aims to explore the positioning of these firms in biopharmaceutical value chain and their path of technological capability building to extract policy-relevant advice.

Design/methodology/approach
As part of a two-year research project, an online questionnaire was designed and sent to biopharmaceutical experts in Iran between May and October 2016. Respondents came from biopharmaceutical firms. Also, 12 semi-structured interviews were conducted to analyze the path of capability building in Iranian biosimilar-producing firms.

Findings
The findings show that Iranian biopharmaceutical firms (BPFs) are mostly concentrated on “pharmaceutical development,”, “drug manufacturing” and “ after-sales services’ activities.” The study also demonstrates that most BPFs in Iran are at the “assimilative” level of capability and a few of them have recently moved toward the “adaptive” level.

Originality/value
The findings show that Iranian BPFs are mostly concentrated on “pharmaceutical development,” “drug manufacturing” and “after-sales services” activities. The study also demonstrates that most BPFs in Iran are at the “assimilative” level of capability and a few of them have recently moved toward the “adaptive” level.
Can coaching leadership encourage subordinates to speak up? Dual perspective of cognition-affection
Authors: Yuan Chuqin , Wang Yanfei , Huang Wenyuan , Zhu Yu 
Published: June 2019

PurposeThe purpose of this paper is to explore the influencing mechanism of coaching leadership (CL) on employee voice behavior (VB) based on cognitive-affective system theory of personality (CAPS). Specifically, the study intends to build a model of psychological security (PS) and openness to change (OC) that mediate the relationship between CL and employee VB at an individual-level and group-level from cognitive-affective dual perspective.Design/methodology/approachCL, employee VB, PS and OC were assessed in an empirical study based on a supervisor–subordinate dyads sample of 287 employees and 72 team leaders from enterprises in Southern China.FindingsFrom CAPS theory perspective, the authors found that CL promotes employee VB and that PS and OC mediate the relationship between CL and VB.Practical implicationsResults underscore the importance of encouraging managers to engage in CL behaviors, which are conductive to enhancing employee PS and OC thereby improving employee VB. These results also highlight the significance of managerial attention to a secure voice atmosphere and the improvement of employees’ affective commitment to organizational change.Originality/valueThe research findings provide a significant contribution to the literature in that it shows PS and OC as crucial dual mediating mechanism through which CL influences VB. Moreover, this paper is one of the few studies answering the call to examine the effect of leadership at multiple levels.
Assessment of quality of information available over the internet about vegan diet
Authors: El Jassar Olivia Genevieve , El Jassar Isobel Nadia , Kritsotakis Evangelos I. 
Published: June 2019

Purpose
This paper aims to assess the quality of health information available to patients seeking online advice about the vegan diet.

Design/methodology/approach
A cross-sectional sample of patient-oriented websites was selected by searching for “Vegan diet” in the three most popular search engines. The first 50 websites from each search were examined. Quality of information was assessed using the DISCERN instrument, a questionnaire tool designed to judge the quality of written information on treatment choices. Readability was determined with the Flesch Reading Ease score (FRES) and Flesch–Kincaid Grade Level (FKGL). Relevance to health and disease was assessed by counting the appearances of ten related keywords, generated by searching the query term “Vegan diet” into PubMed and recording the top ten health-related words.

Findings
Of 150 websites retrieved, 67 (44.7 per cent) met inclusion criteria. Of these, 42 (62.7 per cent) were non-pharmaceutical commercial, 7 (10.4 per cent) institutional, 6 (9.0 per cent) magazines or newspapers, 4 (6.0 per cent) support websites, 4 (6.0 per cent) charitable websites, 2 (3.0 per cent) encyclopedias and 2 (3.0 per cent) personal blogs. The overall DISCERN rating of the websites was fair (mean 41.6 ± 15.4 on an 80-point scale), but nearly half (31/67) of the websites were assessed as having “poor” or “very poor” quality of information. FRES and FKGL readability indices met the recommended standards on average (means 63.3 ± 9.6 and 6.6 ± 1.7, respectively), but did not correlate with high DISCERN ratings. Analysis of variance on DISCERN scores (F(6,60) = 6.536, p < 0.001) and FRES (F(6,60) = 2.733, p = 0.021) yielded significant variation according to website source type.

Originality/value
Quality standards of health information available on the internet about the vegan diet vary greatly. Patients are at risk of exposure to low quality and potentially misleading information over the internet and should be consulting dietitians or physicians to avoid being misled.
The global rise of “fake news” and the threat to democratic elections in the USA
Authors: Lee Terry 
Published: June 2019

Purpose
Since the end of 2016, “fake news” has had a clear meaning in the USA. After years of scholarship attempting to define “fake news” and where it fits among the larger schema of media hoaxing and deception, popular culture and even academic studies converged following the 2016 US presidential election to define “fake news” in drastically new ways. The paper aims to discuss these issues.

Design/methodology/approach
In light of the recent elections in the USA, many fear “fake news” that have gradually become a powerful and sinister force, both in the news media environment as well as in the fair and free elections. The scenario draws into questions how the general public interacts with such outlets, and to what extent and in which ways individual responsibility should govern the interactions with social media.

Findings
Fake news is a growing threat to democratic elections in the USA and other democracies by relentless targeting of hyper-partisan views, which play to the fears and prejudices of people, in order to influence their voting plans and their behavior.

Originality/value
Essentially, “fake news” is changing and even distorting how political campaigns are run, ultimately calling into question legitimacy of elections, elected officials and governments. Scholarship has increasingly confirmed social media as an enabler of “fake news,” and continues to project its potentially negative impact on democracy, furthering the already existing practices of partisan selective exposure, as well as heightening the need for individual responsibility.
Child care stress and anxiety in police officers moderated by work factors
Authors: McCanlies Erin C. , Mnatsakanova Anna , Andrew Michael E. , Violanti John M. , Hartley Tara A. 
Published: June 2019

Purpose
Balancing work and family in dual-earner households can be stressful. Research suggests that increased work-family conflict (WFC) significantly predicts poor psychological health and increased stress in police officers. The purpose of this paper is to assess whether child care stress was associated with anxiety symptoms and if stressful work events and shift work modified this relationship among 163 Buffalo, NY police officers.

Design/methodology/approach
Participants indicated child care stress by reporting how much stress they felt (0 – none to 10 – high) when making child care/daily living arrangements. Shiftwork was assessed from pay-roll data (1994 to date of exam) and by asking, “Do you work opposite shift from your spouse/partner to care for your children?” to assess partner’s shift. The Beck Anxiety Scale and Spielberger Police Stress Survey were used to assess anxiety and work stress, respectively. Effect modification was assessed by stratifying on police stress scores using their median values, and on partner’s shift. All models were adjusted for age, alcohol intake, sex and smoking status.

Findings
Results suggest that child care stress was positively associated with anxiety symptoms and that this relationship was moderated by high (>median) work stress factors and afternoon/midnight shift-work, but not having a partner who works opposite shift. These results indicate that child care stress is associated with anxiety symptoms and that this relationship may be modified by work factors.

Research limitations/implications
A number of limitations should be considered while interpreting the results. This study is cross-sectional, which prevents causal inferences; therefore, the temporal pattern between exposure and outcome cannot be determined. The independent, dependent and moderating variables are all self-report measures, which may introduce recall bias. Lastly, generalizability is limited to police departments of similar size and geographic area.

Practical implications
Police experience high stress as part of their jobs, these results indicate that similar to other professions, WFC can also affect police officers, and is associated with higher levels of anxiety.

Originality/value
Few research studies have evaluated the affects of family issues in police. Specifically, the relationship between child care stress and anxiety, and how this relationship may be modified by high work stress.
Automated storage and active cleaning for multi-material digital-light-processing printer
Authors: Matte Christopher-Denny , Pearson Michael , Trottier-Cournoyer Felix , Dafoe Andrew , Kwok Tsz Ho 
Published: June 2019

PurposeThe purpose of this paper is to introduce a novel technique for printing with multiple materials using the DLP method. Digital-light-processing (DLP) printing uses a digital projector to selectively cure a full layer of resin using a mask image. One of the challenges with DLP printing is the difficulty of incorporating multiple materials within the same part. As the part is cured within a liquid basin, resin switching introduces issues of cross-contamination and significantly increased print time.Design/methodology/approachThe material handling challenges are investigated and addressed by taking inspiration from automated storage and retrieval systems and using an active cleaning solution. The material tower is a compact design to facilitate the storage and retrieval of different materials during the printing process. A spray mechanism is used for actively cleaning excess resin from the part between material changes.FindingsChallenges encountered within the multi-material DLP technology are addressed and the experimental prototype validates the proposed solution. The system has a cleaning effectiveness of over 90 per cent in 15 s with the build area of 72 inches, in contrast to the previous work of 50 per cent cleaning effectiveness in 2 min with only 6 inches build area. The method can also hold more materials than the previous work.Originality/valueThe techniques from automated storage and retrieval system is applied to develop a storage system so that the time complexity of swapping is reduced from linear to constant. The whole system is sustainable and scalable by using a spraying mechanism. The design of the printer is modular and highly customizable, and the material waste for build materials and cleaning solution is minimized.
Do mergers and acquisitions create value?
Authors: Reddy Krishna , Qamar Muhammad , Yahanpath Noel 
Published: June 2019

Purpose
The purpose of this paper is to study whether mergers and acquisitions (M&As) create value in Indian and Chinese markets.

Design/methodology/approach
The authors study abnormal returns (AR) created by the acquiring firms in Indian and Chinese markets relating to M&A announcements, using the following three different statistical methods: i.e. mean, market and ordinary least squares adjusted return models.

Findings
On average, M&A announcements do not create value for the firms in Chinese and Indian economies. For the mean model, M&As create value for Chinese firms, whereas for the Indian firms no such value is created for the same event windows. The regression results showed that debt has a positive impact on the AR and cumulative average abnormal returns at 1, 5 and 10 per cent significance levels, respectively.

Research limitations/implications
This study suggests increasing the sample size and period and using the instrumental variables regression to ensure the estimator’s impartiality, consistency and efficiency. With the investigative period surrounding a financial crisis, the estimators may have omitted bias.

Originality/value
Multiple methods used in this paper made it possible to capture the level of method variance in the AR, which is unusual in the Chinese and Indian context. Hence, the current study provides local knowledge and further strengthens the literature about M&As. The authors also regress AR with firm-specific factors, the consideration of which is scarce in the previous literature. Furthermore, much of what the authors know about M&A is relevant to developed economies.
Liquidity hedging with futures and forward contracts
Authors: Shin Yong Jae , Pyo Unyong 
Published: June 2019

Purpose
This paper aims to develop hedging strategies using both futures and forward contracts and issuing risky debt when financially constrained firms are forced to operate in long horizon.

Design/methodology/approach
The authors present a model for developing hedging strategies using both futures and forward contracts and issuing risky debt. A theoretical model employing stochastic differential equations for forward hedging is illustrated with a numerical example over parameter values consistent with the literature.

Findings
A financially constrained firm with limited cash balance must hedge its liquidity with both future and forward contracts and issue risky debt to support its long-term operations. The firm can issue a minimal amount of risky debt by adding forward contracts into hedging and can increase its value higher than that when hedging with only futures contracts. We show numerically that hedging with both futures and forward contracts allows the firm to issue minimal risky debt in increasing its firm value.

Practical implications
When Metallgesellschaft nearly collapsed in 1993, it offered long-term forward contracts to its customers and attempted to hedge its risk by rolling over series of short-term futures contract. It created the situation of inherent mismatch in maturity structure. A financially constrained firm operating in a long horizon appears to commit its liquidity as long-term forward contracts, which cannot be fully hedged with series of futures contacts. The firm should hedge its liquidity with both futures and forward contracts and avoid liquidation with deadweight costs in its long-term operation.

Originality/value
This is the first study examining hedging strategies with both futures and forward contracts.
Acquirer size, political connections and mergers and acquisitions performance
Authors: Zhao Xi , Ma Huanyu , Hao Ting 
Published: June 2019

Purpose
The purpose of this paper is to empirically examine the relationships between acquirer size and performance outcomes of the different process of acquisition in the Chinese context and the moderating effect of political connections on the size-performance relationship.

Design/methodology/approach
Building upon agency theory, the paper examines the relationship between acquirer size and acquisition announcement returns to find whether the acquirer size effect exists in China. Moreover, the paper investigates whether large firms can perform better in the long run arising from scale economy. Finally, the paper examines the moderating effect of political connections on the size-performance relationship. Accounting for the complexity of political connections in China, the paper uses two methods to capture political connections.

Findings
The paper finds that acquirer size plays a significant negative role on announcement returns, suggesting that the acquirer size effect also exists in China. However, acquirer size has a significant positive impact on long-term performance, indicating that large acquirers perform better in the integration process. Although no evidence shows that political connections can bring some off-setting benefits to acquirer size effect argued by Humphery-Jenner and Powell (2014), political connections, indeed, have a positive effect on mergers and acquisitions (M&As) announcement returns.

Originality/value
The paper contributes to the corporate characteristic, political connections and M&A performance literature. Due to agency problem and scale economy, the effect of firm size on acquisition performance varies with the stage of M&A. Political connections can bring some benefits to M&A deals.
An integration team’s diagnosing of context, spanning boundaries and creating psychological safety within a multiteam system
Authors: Huggins Ronald Archie Charles , Scheepers Caren Brenda 
Published: June 2019

PurposeThe purpose of this study is to explore how integration teams can build trusting relationships in component teams to enhance their leadership capability within multiteam systems to achieve common superordinate goals. The study investigates how an integration team diagnoses contextual dynamics to enhance understanding of goals in component teams and spans boundaries to create trusting relationships.Design/methodology/approachThe proposed model was tested by surveying 396 respondents nested within component teams working within five South African manufacturing companies. Structural Equation Modeling was used to analyse the data.FindingsThe study reveals that by diagnosing the contextual dynamics within a multiteam system and through boundary spanning, an integration team builds trusting relationships, which will, ultimately, enable teams to achieve common superordinate goals.Practical implicationsThis study offers organisations insights into how multiple component teams of different functional disciplines can work effectively towards achieving an overall or common superordinate goal. It offers insights on how to mitigate misalignment challenges by implementing an integration team within the multiteam system context.Originality/valueResearch participants were employees within a manufacturing context, which sets this study apart from many previous ones conducted in a simulated environment within a military context. The study investigates building trusting relationships among multiple component teams within a multiteam system through the implementation of an integration team, which has not been specifically addressed in previous studies.
Efficacy and safety of topical OPA‐15406, a new phosphodiesterase 4 inhibitor, in Japanese patients with atopic dermatitis for 8 weeks: A phase 2, randomized, double‐blind, placebo‐controlled study
Authors: Saeki Hidehisa , Kawashima Makoto , Sugaya Satoko , Oshiden Kazuhide , Tsubouchi Hidetsugu 
Published: June 2019

AbstractThe efficacy and safety of topical OPA‐15406, a new phosphodiesterase 4 inhibitor, were examined in Japanese patients aged 15–70 years with atopic dermatitis in a phase 2, randomized, double‐blind, vehicle‐controlled study. Two hundred patients were randomized to three treatment groups at a 1:1:1 ratio to receive OPA‐15406 0.3%, OPA‐15406 1% or vehicle ointment twice daily for 8 weeks. The OPA‐15406 1% group was superior to the vehicle group in terms of the incidence of success based on the Investigator Global Assessment score at week 4 (P = 0.0328), which was the primary end‐point, while the OPA‐15406 0.3% group showed a trend toward improvement in the primary end‐point. The mean Eczema Area and Severity Index total score and subscale (erythema, induration/papulation, excoriation and lichenification) scores, the Visual Analog Scale pruritus score and the Patient‐Oriented Eczema Measure score were significantly improved and the percentage of affected body surface area was significantly decreased in both OPA‐15406 groups relative to the vehicle group as early as week 1, and the improved scores and decreased percentages were generally maintained until week 8. No deaths or serious treatment‐emergent adverse events occurred in the OPA‐15406 treatment groups. Treatment‐emergent adverse events frequently observed across treatment groups were worsening of atopic dermatitis, viral upper respiratory tract infection and pruritus, all of which were mild or moderate in severity in the OPA‐15406 groups. OPA‐15406 1% ointment showed favorable efficacy and safety profiles, indicating a promising treatment option for patients with atopic dermatitis.
UK criteria for uterus transplantation: a review
Authors: Hammond‐Browning N 
Published: June 2019

Absolute uterine factor infertility is the final hurdle for assisted reproductive treatments. Uterus transplant trials are happening worldwide; to advance the debate around uterine transplantation (UTx), this article considers selection criteria for clinical trials from a UK perspective and makes recommendations for future selection criteria for UTx treatment. Recommendations advanced include the use of donor eggs, access for single women and women in same‐sex relationships, prohibiting participation of women who are already mothers, and a preference for deceased donors and bioengineered uteri. With UTx treatment on the horizon, it is important to proactively consider future selection criteria.Tweetable abstractReview of UK selection criteria for clinical trials for uterus transplantation; recommendations for the future.
Evaluating Agricultural Productivity and Policy in Russia
Authors: Rada Nicholas , Liefert William , Liefert Olga 
Published: June 2019

AbstractRussia's transition to a market economy in the early 1990s shocked its agricultural sector, creating the potential for profit and gains from specialisation and productivity improvements. However, subsequent regional agricultural development has been highly uneven, and the sources of the sector's productivity improvement remain unclear. Drawing on a newly‐assembled Russian regional farm production and policy dataset, we evaluate agricultural total factor productivity growth from 1994 to 2013, decomposing that growth into technical progress and efficiency gains, for the nation as a whole and for the major agricultural districts of the South and Central. We then test how investments in road and rail infrastructure and human capital have influenced those gains. The South substantially outperformed the Central district and the nation at large with respect to all three performance indicators. However, contrary to the literature, we find that these particular state policies provided no substantial growth advantages, there or elsewhere. Rather, the dominant force behind Russia's agricultural growth has been informal technical change.