bluuebunny/crossref_metadata_2025_split huggingface dataset:
Approaching the Century Jubilee (Interview with the Rector D.A. Endovitsky)
Authors: Endovitsky D. A. 
Published: October 2018

In his interview, the Rector of Voronezh State University highlights the milestones of VSU’s history and its achievements during the centennial working experience. The history of Voronezh State University goes back to 1918, when the staff and students of Yuriev (former Derpt) University moved to Voronezh owing to the German occupation of Estonia. Today Voronezh State University is one of most renowned universities in Russia, the largest research university in the Central Black Earth Region. Its world competitiveness can be demonstrated by the fact that VSU is listed among the top universities in international and national rankings such as Quacquarelli Symonds (QS) World University Ranking, Times Higher Education (THE) World University Ranking, Interfax, Rating of Russian universities. The advanced forms of interaction between University and business partners and enterprises were described, such as centers of corporate training (VSU has more than 10) and corporate postgraduate courses (cooperation with PriceWaterhouseCoopers, Bionorica SE and others). The University is piloting the convergent educational programs, e.g. “Medical cybernetics”, mathematical modeling in pharmaceutical studies, experimental technical school for gifted children.
Even better than the real thing? Using video assisted structured reflection in Simulated Clinical Scenarios and Real-Life Clinical Experiences in the Flipped Classroom.
Authors: O'Connor Chris , O'Hara Joe 
Published: October 2018

<p><strong>Background</strong></p><p>This paper explores the attitudes of practitioners to the use of video assisted structured reflection in simulated clinical scenarios and real-life clinical experiences in the context of a Flipped Classroomto encourage and support reflection and reflective practice among pre-hospital emergency care practitioners in Ireland. It also examines the experiences of practitioners who participated in this process.</p><p><strong>Methodologies</strong></p><p>This paper is part of a larger project which consisted of tree cycles of action research. Data was collected via an online survey questionnaire, and by conducting a series of semi-structured interviews with various stake-holders. These included all three clinical levels of pre-hospital emergency care practitioners and educators from emergency service providers, private ambulance services, and voluntary organisations.</p><p><strong>Findings</strong></p><p>When combined, a simulation experience with audio-visual recording and a structured model of reflection in the context of a Flipped Classroom has become a powerful learning experience. The process of a simulation experience with audio-visual recording, and a structured model of reflection appears to dovetail very nicely with the concept of the Flipped Classroom. The review of footage from audio-visual recording in the real-life clinical context provides a reliable and accurate means of evaluating clinical performance. Concerns were raised about the potential for abuse and misuse of audio-visual recordings. There are perceptions that audio-visual footage of real-life clinical experiences could potentially be used for unintended purposes such as, disciplinary procedures.</p><p><strong>Recommendations</strong></p><p>Since the process of combining a simulation experience with audio-visual recording and a structured model of reflection in the context of a Flipped Classroom has shown great promise as a learning experience, a larger scale pilot study is proposed. Develop a pilot programme with student practitioners during their undergraduate internship, and evaluate its findings. Develop a policy which clearly defines the use of audio-visual recording footage prior to the commencement of the pilot programme. A Learning Contract for all participants and faculty, including a confidentiality agreement, must be in place prior to the establishment of the process.</p>
Low Pass Filter Design With Artificial Ground Structure
Authors: Gunawan Wahyu Hendra , Oktafiani Fitri , Sugeng Bambang , Lukman Lukman 
Published: October 2018

In this paper, low pass band filter with via holes and using artificial ground structure are proposed. The design contains a u-shaped parasite element and gives via hole which is connected to the ground on the adjacent side with a copper. A hole in this design has a diameter 1 mm. The A have the form square 15mm x 17.5mm, given an effect, if compared with the non-artificial ground structure system, this addition show that the bandwidth of the low pass filter is shifting regarding this condition with value 400Mhz at frequency 1GHz.On this paper, the low pass filter also gives the pass band filter on frequency 3.2GHz which is constructed by the artificial ground structure. The simulation results with this design are simulated by computer based on finite integration method and show a good agreement and can be performed for a low pass band filter applications in the future. Keywords: low pass filter, less via, artificial ground structure
Multiple Modal Features and Multiple Kernel Learning for Human Daily Activity Recognition
Authors: Vo Viet Hoai , Pham Hoang Minh 
Published: October 2018

Introduction: Recognizing human activity in a daily environment has attracted much research in computer vision and recognition in recent years. It is a difficult and challenging topic not only inasmuch as the variations of background clutter, occlusion or intra-class variation in image sequences but also inasmuch as complex patterns of activity are created by interactions among people-people or people-objects. In addition, it also is very valuable for many practical applications, such as smart home, gaming, health care, human-computer interaction and robotics. Now, we are living in the beginning age of the industrial revolution 4.0 where intelligent systems have become the most important subject, as reflected in the research and industrial communities. There has been emerging advances in 3D cameras, such as Microsoft's Kinect and Intel's RealSense, which can capture RGB, depth and skeleton in real time. This creates a new opportunity to increase the capabilities of recognizing the human activity in the daily environment. In this research, we propose a novel approach of daily activity recognition and hypothesize that the performance of the system can be promoted by combining multimodal features.
Methods: We extract spatial-temporal feature for the human body with representation of parts based on skeleton data from RGB-D data. Then, we combine multiple features from the two sources to yield the robust features for activity representation. Finally, we use the Multiple Kernel Learning algorithm to fuse multiple features to identify the activity label for each video. To show generalizability, the proposed framework has been tested on two challenging datasets by cross-validation scheme.
Results: The experimental results show a good outcome on both CAD120 and MSR-Daily Activity 3D datasets with 94.16% and 95.31% in accuracy, respectively.
Conclusion: These results prove our proposed methods are effective and feasible for activity recognition system in the daily environment.
Constraining the Evolution of the Proton Distribution Function in the Heliotail
Authors: Zirnstein E. J. , Kumar R. , Heerikhuisen J. , McComas D. J. , Galli A. 
Published: October 2018

Abstract
We use Interstellar Boundary Explorer (IBEX) measurements of energetic neutral atoms (ENAs) to constrain the proton (mostly pickup ion, PUI) distribution in the heliotail. In our previous study, we solved the Parker transport equation and found that the velocity diffusion coefficient D(v) for PUIs is approximately D(v) ∼ 1.1 × 10−8 km2 s−3 (v/v
0)1.3, assuming the initial proton distribution processed by the termination shock (TS), f

p,0, is a kappa distribution with kappa index κ

p,0 = 1.63. In this study, we test different forms for f

p,0. We find that if f

p,0 is kappa-distributed and D(v) = D
0(v/v
0)1.3, any kappa index in the range 1.5 < κ

p,0 < 10 is consistent with IBEX data if D
0 ∼ 0.8–1.3 × 10−8 km2 s−3. While the case where D(v) ∝ v
1.3 yields ENA fluxes that appear to best reproduce IBEX data for any κ

p,0, it is possible for D(v) to scale close to ∼v
2/3 or ∼v
2 within our uncertainties by changing D
0. We also show that an upstream PUI filled-shell distribution that is heated by a quasi-stationary TS, generating a downstream filled-shell with large cutoff speed, yields an excess of ENAs >2 keV compared to IBEX. However, using a fully kinetic particle-in-cell simulation to process a PUI filled-shell across the TS yields ENA spectra consistent with IBEX, reinforcing the significance of self-consistent, preferential PUI heating and diffusion at the TS. Interestingly, an upstream PUI distribution inferred from the particle-in-cell simulation to reproduce Voyager 2 observations of the nose-ward TS is inconsistent with IBEX observations from the heliotail, suggesting differences in the upstream PUI distribution or TS properties.
Nonlinear Force-free Modeling of Flare-related Magnetic Field Changes at the Photosphere and Chromosphere
Authors: Kleint Lucia , Wheatland Michael S. , Mastrano Alpha , McCauley Patrick I. 
Published: October 2018

Abstract
Rapid and stepwise changes of the magnetic field are often observed during flares but cannot be explained by models yet. Using a 45 minute sequence of Solar Dynamics Observatory/Helioseismic and Magnetic Imager 135 s fast-cadence vector magnetograms of the X1 flare on 2014 March 29 we construct, at each timestep, nonlinear force-free models for the coronal magnetic field. Observed flare-related changes in the line-of-sight magnetic field B
LOS at the photosphere and chromosphere are compared with changes in the magnetic fields in the models. We find a moderate agreement at the photospheric layer (the basis for the models), but no agreement at chromospheric layers. The observed changes at the photosphere and chromosphere are surprisingly different, and are unlikely to be reproduced by a force-free model. The observed changes are likely to require a change in the magnitude of the field, not just in its direction.
EPIC 203868608: A Low-mass Quadruple Star System in the Upper Scorpius OB Association
Authors: Wang Ji , David Trevor J. , Hillenbrand Lynne A. , Mawet Dimitri , Albrecht Simon , Liu Zibo 
Published: October 2018

Abstract
Young multiple star systems provide excellent testing grounds for theories of star formation and evolution. EPIC 203868608 was previously studied as a triple star system in the Upper Scorpius OB association, but the followup Keck NIRC2/HIRES/NIRSPAO observations reported here reveal its quadruple nature. We find that the system consists of a double-lined spectroscopic binary (SB2) Aab (M5+M5) and an eclipsing binary (EB) Bab with a total mass that is lower than that of the SB2. Furthermore, we measure the obliquity of the EB using the Doppler tomography technique during the primary eclipse. EPIC 203868608 Bab is likely on an inclined orbit with a projected obliquity of

degrees. The inclined orbit is used to constrain the tidal quality factor for low-mass stars and the evolution of the quadruple system. The analytic framework to infer obliquity that has been developed in this paper can be applied to other EB systems as well as transiting planets.
Effects of antiretroviral combination therapies F/TAF, E/C/F/TAF and R/F/TAF on insulin resistance in healthy volunteers: The TAF-IR Study
Authors: Spinner Christoph D , Schulz Sebastian , Bauer Ulrike , Schneider Jochen , Bobardt Johanna , Werder Alexander Von , Schmid Roland M , Zink Alexander , Wolf Eva , Iakoubov Roman 
Published: October 2018

Background Increased insulin resistance (IR), associated with specific antiretroviral drugs or drug classes, is an established risk factor for type 2 diabetes in HIV patients, ultimately increasing morbidity and mortality. To date, data on the risk of IR in tenofovir alafenamide (TAF)-based protocols are unavailable. Methods This prospective randomized, open-label study evaluated the effects of IR on 30 healthy volunteers receiving fixed-dose combinations (FDCs) of emtricit-abine/tenofovir alafenamide (F/TAF), elvitegravir/cobi-cistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) or rilpivirine/emtricitabine/tenofovir alafenamide (R/F/TAF). IR was measured before and after 14-day treatments using the hyperinsulinemic-euglycaemic clamp technique (HEGC). Changes in IR in each group were evaluated using the mean glucose disposal rate, normalized with body weight (MBW [mg glucose/(minxkg)]). Results A total of 30 subjects underwent randomization: one subject in the F/TAF arm withdrew consent after randomization and one in the R/F/TAF arm had to be excluded because of technical failure during HEGC, resulting in 28 subjects in the per-protocol population (F/TAF, n=9 subjects; E/C/F/TAF, n=10 subjects; R/F/TAF n=9 subjects). No significant differences were detected on the baseline characteristics. IR did not differ among the groups before treatment. None of the studied anti-retroviral combinations resulted in a significant change in IR after 14 days compared with baseline values, as measured by MBW (F/TAF, 11.42 ±3.04 mean [±sd] versus 11.43 ±3.23, P=0.49; E/C/F/TAF, 10.04 ±2.49 versus 10.95 ±4.26, P=0.30; R/F/TAF, 11.03 ±1.96 versus 13.01 ±4.11, P=0.13). Conclusions Short-term treatment for F/TAF, E/C/F/TAF or R/F/TAF did not increase IR in healthy male volunteers.
VASP Regulates NK Cell Lytic Granule Convergence
Authors: Wilton Katelynn M. , Billadeau Daniel D. 
Published: October 2018

Abstract
NK cells eliminate viral-infected and malignant cells through a highly orchestrated series of cytoskeletal rearrangements, resulting in the release of cytolytic granule contents toward the target cell. Central to this process is the convergence of cytolytic granules to a common point, the microtubule-organizing center (MTOC), before delivery to the synapse. In this study, we show that vasodialator-stimulated phosphoprotein (VASP), an actin regulatory protein, localizes to the cytolytic synapse, but surprisingly, shows no impact on conjugate formation or synaptic actin accumulation despite being required for human NK cell–mediated killing. Interestingly, we also find that a pool of VASP copurifies with lytic granules and localizes with lytic granules at the MTOC. Significantly, depletion of VASP decreased lytic granule convergence without impacting MTOC polarization. Using the KHYG-1 cell line in which lytic granules are in a constitutively converged state, we find that either VASP depletion or F-actin destabilization promoted spreading of formerly converged granules. Our results demonstrate a novel requirement for VASP and actin polymerization in maintaining lytic granule convergence during NK cell–mediated killing.
A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice
Authors: Zheng Huiwen , Wang Jingjing , Li Bingxiang , Guo Lei , Li Heng , Song Jie , Yang Zening , Li Hongzhe , Fan Haitao , Huang Xing , Long Haiting , Cheng Chen , Chu Manman , He Zhanlong , Yu Wenhai , Li Jiaqi , Gao You , Ning Ruotong , Li Nan , Yang Jinxi , Wu Qiongwen , Shi Haijing , Sun Ming , Liu Longding 
Published: October 2018

Abstract
Enterovirus D68 (EV-D68) belongs to the picornavirus family and was first isolated in CA, USA, in 1962. EV-D68 can cause severe cranial nerve system damage such as flaccid paralysis and acute respiratory diseases such as pneumonia. There are currently no efficient therapeutic methods or effective prophylactics. In this study, we isolated the mAb A6-1 from an EV-D68–infected rhesus macaque (Macaca mulatta) and found that the Ab provided effective protection in EV-D68 intranasally infected suckling mice. We observed that A6-1 bound to the DE loop of EV-D68 VP1 and interfered with the interaction between the EV-D68 virus and α2,6-linked sialic acids of the host cell. The production of A6-1 and its Ab properties present a bridging study for EV-D68 vaccine design and provide a tool for analyzing the process by which Abs can inhibit EV-D68 infection.
Can probiotic cleaning solutions replace chemical disinfectants in dental clinics?
Authors: Al-Marzooq Farah , Bayat Shahad Al , Sayyar Farah , Ishaq Hamdah , Nasralla Husain , Koutaich Rayan , Kawas Sausan Al 
Published: October 2018

ABSTRACT
Objectives: We aim to assess the antibacterial effectiveness of probiotic cleaning in a dental clinic at the University Dental Hospital Sharjah (UDHS), UAE. Materials and Methods: The current cleaning protocol of UDHS was evaluated by the surface swabbing of three dental clinics routinely cleaned using regular chemical disinfectants. Then, a new probiotic cleaning solution containing Bacillus subtilis was applied for 3 weeks in a selected clinic. Bacteria were grown onto selective culture media for colony counting from surfaces cleaned with probiotic solution compared to those obtained from the same surfaces cleaned with the regular chemical solutions. Isolates identity was confirmed by biochemical tests or polymerase chain reaction. Results: There was a significant reduction of the bacterial counts of various bacterial species (Staphylococci, Streptococci, and Gram-negative rods) from almost all the surfaces in the dental clinic after the application of the probiotic solution compared to the same surfaces cleaned with the regular chemical solutions. However, the antibiotic resistance rates were not significantly reduced within the short period of 3 weeks of using the new probiotic cleaning product. Conclusions: This study demonstrated that the use of probiotic cleaning is effective in reducing microbial growth in dental settings. This approach may be tested further to examine the long-term effect and to evaluate the opportunity of applying this novel biotechnology as part of the infection control routine in dental settings instead of the chemical disinfectants which are known to cause serious health problems. This is the first study testing the application of probiotic-based solution in dental settings.
Dental trauma education intervention as a positive influence among undergraduate students
Authors: Nagata Juliana Yuri , Góis Vanessa Lima de Andrade , Münchow Eliseu Aldright , Albuquerque Maria Tereza Pedrosa 
Published: October 2018

ABSTRACT
Objective: To investigate the effect of dental trauma educational intervention among undergraduate students of a Federal University in Brazil. Materials and Methods: Students (n = 125) enrolled in the dentistry (n = 70), nursing (n = 33), and speech therapy (n = 22) courses were invited to attend a dental trauma lecture and also to answer a questionnaire about their confidence in managing crown fracture and tooth avulsion, before (T0) and immediately after (T1) the lecture. McNemar's test (P < 0.05) with logistic regression compared the answers between the courses. Results: Female gender (78.4%) aged from 18 to 22 years (73.6%) predominated among all the participants. Dentistry students scored higher correct answers (54.3%) in T0 when compared to nursing (12%) and speech therapy (9%) students, concerning the storage medium for tooth fragment transportation. Likewise, few dentistry students (22.9%) and no nursing and speech therapy students knew about the ideal storage medium for an avulsed tooth when immediate replantation was unviable. After educational intervention, a significant improvement was found between T0 and T1 (P < 0.001) for all courses, mainly regarding tooth avulsion with almost 100% of correct answers. Furthermore, logistic regression demonstrated that dentistry students had three times more knowledge absorption than nursing and speech therapy ones. Conclusions: The educational intervention demonstrated a significant positive impact regarding the knowledge of dental trauma emergency management among health students. Accordingly, it is essential to spread this information among health professionals to save teeth, especially in cases of avulsion.
Mechanical and surface properties analysis of restorative materials submitted to erosive challenges in situ
Authors: Guedes Ana Paula Albuquerque , Oliveira-Reis Bruna , Catelan Anderson , Suzuki ThaÍs Yumi Umeda , Briso André LuÍz Fraga , Santos Paulo Henrique Dos 
Published: October 2018

ABSTRACT
Objective: This study aims to evaluate the effect of acidic solutions (AS) on surface roughness (Ra) and microhardness of restorative materials (RM). Materials and Methods: Eight volunteers wore intraoral palatal devices (IPD) containing samples of RM: Ketac Nano (KN); Ketac Nano + Biscover LV (KN-B); Esthet-X (EX); Esthet-X + Biscover LV (EX-B); Supreme XT (SXT); Supreme XT + Biscover LV (SXT-B); and bovine enamel. The samples were submitted to three phases: (1) immersion in 0.01M hydrochloric acid (HCl) – 10 min, three times/day (14 days); (2) immersion in soft drink (Sprite®) – 10 min, three times/day (14 days); and (3) keeping in saliva (14 days). Changes in Ra/microhardness were measured before/after the three phases. Statistical Analysis: ANOVA (α = 0.05) and Fisher's test. Results: Materials sealed with Biscover LV (B) presented lowest values in all periods. KN glass ionomer cement showed highest Ra values after exposure in AS. Application of B did not reduce the Ra for the composites studied, except for EX after immersion in HCl. AS promoted changes in Ra/microhardness of RM, except for sealed materials. Conclusions: The acids used were able to change the Ra and microhardness of RM, except of the sealed materials. The resin-modified GIC showed the most significant changes after immersion in AS; and the composites sealed with B, even after immersion in acidic solutions (AS), showed the lowest Ra values and the least degradation in microhardness, especially when subjected to low pH solutions.
The effect of resistance grooves on the fracture toughness of zirconia-based crowns from mono and cyclic loading
Authors: Qasim Tarek Q. , El-Masoud Billal M. , Laban Ahmed M. Abu 
Published: October 2018

ABSTRACT
Objective: Prosthetic molar crowns in service are subjected to chewing loads, which cause a shift or dislodgment. The objective of this study is to investigate whether the addition of resistance grooves to the proximal surfaces of the abutment teeth would enhance the fracture resistance of the zirconia crowns and to compare between the patterns of cracks development on the zirconia crowns after the application of mono loading versus cyclic loading forces. Materials and Methods: Thirty-six all-ceramic zirconia cored crowns were prepared on the same abutment. Resistance grooves were added to the mesial and distal surfaces of 16 abutments. Before testing, all specimens subjected to thermal aging. Two groups of crowns were then subjected to cyclic axial and lateral forces for 1,250,000 cycles in aqueous conditions. Two groups of samples were also tested in monoloading fashion. Results: The crack pattern between mono and cyclic loading were compared. The crown fracture resistance was compared in the two types of abutments, with and without grooves. The results confirmed that the grooves addition had no effect on critical conditions to initiate failure in the case of mono loading. In cyclic loading, grooves addition increased the critical loads in the order of two. Failure patterns and location were obtained. Conclusions: The results showed that the location of retention grooves halted the failure in the surfaces where it was located in all loading mechanisms used in this study.