bluuebunny/crossref_metadata_2025_split huggingface dataset:
Habilidades teóricas y prácticas para flebotomía entre alumnos de primer semestre de medicina en el Centro de Simulación Montagne, Mérida - México
Authors: Cetina-Sauri Gregorio , Puga-Matú Herbert , Chávez-Medina Jaidy , Cambranis-Romero Joeana , Aguilar-Vargas Esteban , Méndez-Domínguez Nina 
Published: June 2018

Introducción. El uso de simuladores de pacientes humanos es una estrategia eficaz en la enseñanza de procedimientos clínicos. Sin embargo, existe poca información para ayudar a los profesores a mejorar sus estrategias docentes permitiéndoles mejorar las experiencias de aprendizaje de acuerdo a la edad o el sexo de los alumnos que emplean este tipo de simulación. Objetivos. Identificar si existen diferencias por sexo o edad en asociación a las habilidades de los alumnos del primer semestre de medicina para la flebotomía. Diseño. Cuasiexperimental. Lugar. Centro de Simulación Médica Montagne de la Universidad Marista de Mérida. Participantes. Estudiantes de primer semestre de la licenciatura en medicina. Intervenciones. Intervención educativa del proceso de flebotomía con toma de muestra, empleando simuladores de alta fidelidad. Para el análisis, se evaluó la asociación de las variables de edad y sexo con el desempeño de los alumnos. Principales medidas de los resultados. Se analizaron las evaluaciones prácticas y teóricas. Para la evaluación práctica se aplicó una rúbrica de 20 ítems y se promediaron las puntuaciones de las esferas teóricas y prácticas de los alumnos. Resultados. Se identificó que las mujeres desempeñaron mejor sus habilidades prácticas (p<0,03) aún en el modelo de regresión lineal ajustado por edad y grupo. Discusión. El mejor desempeño en la práctica de flebotomía entre las alumnas de medicina difícilmente sea un hallazgo aislado, pues puede derivarse de las habilidades para la comunicación interpersonal, misma que también puede ser reforzada en los alumnos del sexo masculino.
Diagnóstico de tuberculosis en el marco de la evaluación periódica ocupacional: observaciones a la actual normativa peruana
Authors: Jhonston Erik J. , Alarcon-Ruiz Christoper A. , Miñan-Tapia Armando , Taype-Rondan Alvaro 
Published: June 2018

Sr Editor, en Perú la Ley de Seguridad y Salud en el Trabajo vigente establece que el empleador es responsable de proteger la salud de sus trabajadores mediante actividades como los exámenes médico ocupacionales (EMO), que según la Resolución Ministerial (RM) 312-2011 del Ministerio de Salud (MINSA) son obligatorios para cada actividad económica (1). Si bien esta RM ha implicado un avance en la salud ocupacional peruana, presenta ciertas falencias con respecto al tamizaje de tuberculosis, que podrían estar impidiendo un diagnóstico certero en la población vulnerable.
Fogágybetegség kezelésének hatása a terhesség kimenetelére
Authors: Novák Tibor , Radnai Márta , Kozinszky Zoltán , Práger Nándor , Hodoniczki László , Gorzó István , Németh Gábor 
Published: June 2018

Abstract: Introduction: Correlations between periodontitis and its effects on the outcome of pregnancies are actually more focused topics. Maternal motivation for a good oral hygiene and preventive dental treatment must be highlighted tasks during pregnancy care. Aim: The authors analysed the effect of the preventive dental treatment during pregnancy and its obstetrical effects. Method: In a prospective randomised study, including pregnant women observed for threatening preterm deliveries, patients with dental examination (n = 71) were compared with patients undergoing dental treatment at the same time (n = 79). Statistical analysis: Univariate comparisons for categorical variables were assessed by χ2 tests and independent Student’s t-tests for continuous variables. ORs were compared with Mantel–Haenszel tests. Multivariable logistic regression was performed to evaluate the factors determining the poor periodontal parameters and gingivitis separately. The two-tailed statistical significance level was set at 5%. Results: In the dental treatment group, the neonatal birth weight was significantly higher than in the non-treated group, in case of patients with periodontitis (2990 ± 582.3 g vs 2568.1 ± 699.1 g, p = 0.005). Also the average age at delivery was significantly higher in the treated vs non-treated groups (37.3 ± 1.9 vs 36.0 ± 2.9 weeks, p = 0.027), and the treatment had a beneficial effect on the prolongation of pregnancy, with a higher level of significance in the gingivitis group vs patients with periodontitis groups (p = 0.02 vs p = 0.043). Conclusions: Dental treatment of expecting women has a beneficial effect on the prolongation of pregnancy by decreasing the rate of prematurity and perinatal complications. Orv Hetil. 2018; 159(24): 978–984.
A SOLUTION FOR IMPROVEMENT OF ECG ARRHYTHMIA RECOGNITION USING RESPIRATION INFORMATION
Authors: Linh Tran Hoai 
Published: June 2018

Electrocardiogram (ECG) and respiration signals are two basic and important and valuable biomedical signals as source of information used to determine a person's health status. However, ECG signals are usually of small amplitude and are susceptible to various noises such as: the 50Hz grid noise, poor electrodes’ contacts with the patient's skin, the patient's emotional variations, the respiration and movement of the patient... The idea in this paper by filtering out the effect of the respiration in the ECG signal or by incorporating the information of breathing stage into the ECG signal classification the we can improve the reliability and accuracy of the arrythmia classification. This paper proposes a solution, which uses wavelet filter to reduce the effect of respiration in the ECG signals and will use additional information from the breathing rhythm (when available) to help better classifying the arrythmias. As the main nonlinear classifier we use the classical neuro-fuzzy TSK network. The proposed solution will be tested with data from the MIT-BIH and the MGH/MF databases.
Vinclozolin’ in Galleria mellonella L. (Lepidoptera: Pyralidae)’ nın Erginleşme Süresi ve Eşey Oranı Üzerine Etkisi
Authors: ÖZTÜRK Rahile , AKDOĞAN Yunus 
Published: June 2018

Bu çalışma,
vinclozolinin, arıcılıkta peteklere zarar veren ve ekonomik yönden zararlı bir
tür olan Galleria mellonella (Lepidoptera:
Pyralidae)’ nın bazı fizyolojik özelliklerine etkisini belirlemek amacıyla
yapılmıştır. Deney grupları için, stok kültürlerden elde edilen yumurtalar,
farklı dozlarda (25, 50, 75 ve 100 ppm) vinclozolin karıştırılmış besin içine
bırakılmış ve yumurtadan çıkan larvaların bu besinle beslenmeleri sağlanmıştır.
Sonrasında, bu larvaların erginleşme süreleri ile erginleşen bireylerin eşey
oranları belirlenmiştir. Elde edilen sonuçlara göre, uygulanan vinclozolin
miktarının artmasının erginleşme süresini uzattığı, erginleşme yüzdesini önemli
ölçüde azalttığı ama meydana gelen erginlerin eşey oranlarında kontrol grubuna
göre bir fark oluşturmadığı tespit edilmiştir.
Os usos do corpo: dos sacrifícios “primitivos” às religiões “atuais”- Resenha
Authors: Rigoni Ana Carolina Capellini 
Published: June 2018

No livro Sobre o Sacrifício, Mauss e Hubert falam sobre a função social do sacrifício religioso, que para eles concentra-se na prática de certos rituais realizados com o objetivo de iniciar ou manter o contato com deus, ou ainda deuses, dos quais o indivíduo tem necessidade. Percebemos uma profunda relação entre estes rituais com o corpo do fiel, pois são os gestos realizados durante o ritual que dão significado a ele. Isto torna a obra relevante a todos que se propõem a estudar o corpo em seus aspectos culturais e sociais, pois são diversas as religiões que compõem a sociedade contemporânea.
An Accurate Parametric Method for Assessing Hydrocarbon Volumetrics: Revisiting the Volumetric Equation
Authors: Ma Y. Z. 
Published: June 2018

SummaryOne of the most-important bases for field-development planning is the estimate of hydrocarbon initially in place (HIIP), which has been traditionally estimated either deterministically or by Monte Carlo simulation. The classical volumetric calculation is the most-common deterministic method, and it requires the use of the averages of the reservoir variables and thus does not model the correlations of the input variables. It is well-known that ignoring the correlations among the reservoir variables can lead to incorrect estimations of hydrocarbon volumetrics. The Monte Carlo method uses the input means in the volumetric equation for random simulation of hydrocarbon volumes, yet allows modeling of the correlation between the input parameters. However, using the means and modeling the correlation of the properties are theoretically conflicting. This paper presents new parametric equations for volumetric calculation using mathematical correlation. Unlike the classical volumetric calculation, these equations are the exact expressions of the rigorous hydrocarbon volumetric equation. We discuss how these new equations enable the quantification of inaccuracy in hydrocarbon volumetric estimation by the classical method. Our examples will further show that the magnitude of inaccuracy of the traditional volumetrics depends on the reservoir characteristics; the inaccuracy is generally more significant for heterogeneous, low-quality, and tight reservoirs than for relatively homogeneous high-quality reservoirs.
Scale Risk Assessment and Novel Coating for Smart Completion: Scale Simulation and CFD Modelling Approach
Authors: Guan Hua , Bouamra Reda , Lindvig Thomas , Vernus Jean-Claude 
Published: June 2018

Abstract
There is an increasing demand in using intelligent well completions such as ICV (Inflow Control Valve) due to increased reservoir and production complexity in subsea fields. Failure of a functional ICV due to scale deposition can cause severe production impairment, R&D efforts therefore implemented to qualify a novel coating material which will be used in ICV to prevent scale formation and adhesion. Depending on the geometry of ICV, scaling deposition risks varies; in general increased carbonate scaling are observed due to greater pressure drop gradient.
This paper firstly evaluates the scaling risks over the field lifetime for a pre-salt carbonate reservoir, much increased scaling potential is identified across the region of the ICV which necessities the use of a novel coating. Special laboratory apparatus that simulate the hydrodynamic conditions is designed and tested based on CFD (Computational Fluid Dynamics) results. Intensive modelling using variety of scale software as well as CFD approach are carried out to assess scale risks over the field lifetime, identify the fluid dynamic behavior around the ICV and to investigate the scale formation and adhesion mechanisms and differences onto non-coated vs. coated surfaces. Comparative CFD modelling and laboratory testing results on coated and non-coated surfaces illustrates the much reduced scale accumulation and depositions onto coated materials. CFD modelling of the non-coated vs. coated coupon reactor indicates that the coated surface introduce higher velocity and less turbulence kinetic energy therefore reduce or eliminate surface accumulation and adhesion of scale particles. Lower velocity is observed upstream the ICV choke and around the inflow point, these areas are more prone for scale formation which leads to solid accumulation in the near wellbore region.
This paper highlights the advantages of using advanced modelling techniques (including CFD and integrated PipeSim-ScaleChem models) to assist the selection of realistic testing conditions, to guide the high value test equipment design and to reveal the scaling mechanisms. The implementation of this novel technology helps to mitigate scaling problem and enhance the service longevity of smart completion tool, in particularly for severe scaling fields.
Pensamiento trinitario y metafísica platonista en el De Generatione Divini Verbi de Mario Victorino
Authors: González Nares Gabriel 
Published: June 2018

Mario Victorino Africano (n. ca. 300- m. 382 A.D.) representa elocuentemente el encuentro entre el cristianismo y el pensamiento platonista en el ambiente latino del siglo IV. En una de la obras de Victorino, el De Generatione Divini Verbi Victorino utiliza un aparato filosófico plotiniano para acercarse mejor a la teología cristiana en función de la solución de este problema trinitario: ¿Cómo genera algo el Uno sin dejar de ser Uno? El objetivo de este texto es analizar la convivencia del pensamiento teológico trinitario con la metafísica platonista plotiniana en el De Generatione Divini Verbi en función de dos temas principales: 1) los modos de ser, y 2) la explicación de la vida del Uno más allá de la substancia. Primero 1) daremos una breve semblanza de la vida de Mario Victorino, 2) después, analizaremos por qué el problema cristológico arriano necesita de una metafísica madura y sistemática para resolverse, 3) luego, repasaremos las soluciones que da Victorino en función del problema cristológico enfocándonos en los dos ejes mencionados, y 4) finalmente veremos las conclusiones de esta interacción entre teología y filosofía platonista mencionando la novedades que Victorino aporta a la comprensión de la metafísica platonista plotiniana.
Clostridium perfringens identifies source of pollution and reference streams in a tropical highland environment
Authors: Mushi Douglas 
Published: June 2018

Abstract
Clostridium perfringens was analysed in soils from a tropical highland catchment and corresponding headwater streams at baseflow condition in order to understand the contribution of soils to the microbiological quality of stream water and the feasibility of using these streams as surrogate for negative control (reference streams). The concentrations of C. perfringens depended on the sample matrix. C. perfringens concentrations were significantly higher in the catchment soil than in the stream water (P &lt; 0.05, n = 20). In addition, C. perfringens concentrations in the catchment soil remarkably predicted C. perfringens concentrations in the stream water (i.e., 82% of variations in C. perfringens concentrations in water were predicted by C. perfringens concentrations in soil; P &lt; 0.05, n = 20). This suggests that the catchment soils contributed C. perfringens to the stream water. Despite the observed contamination, the concentrations of C. perfringens (geometric mean of 32 cfu/100 cm3) in the stream water was below the recommended safe level for tropical freshwater systems and extremely lower than that detected in anthropogenically influenced rivers. This concentration was defined as an acceptable level of disturbance, and a reference concentration that can serve as surrogate for negative control in the studied tropical environment.
Removal of synthetic and industrial effluent color by photocatalytic process
Authors: de Paula Soares Bruna , Climaco Leticia Rosa , de Almeida Lariana Negrão Beraldo , Lenzi Giane Gonçalves 
Published: June 2018

Abstract
The present work aimed at evaluating the photocatalytic process as an alternative for color removal from a synthetic solution (methylene blue dye) and of a sample of textile effluent, obtained from the various stages of the process, mainly dyeing. The parameters were evaluated using titanium dioxide (anatase, rutile, commercial and synthetized by the sol-gel method) in order to determine their structural influence in the discoloration of the samples. A synthetic methylene blue dye solution and a real effluent (Brazilian textile industry) were treated. The photocatalytic degradation was carried out over three hours in a batch reactor, under constant agitation, aeration, radiation and temperature. It was observed that the characteristics of each catalyst directly influence the photocatalytic activity. As a result, for the variables used in this work, the photocatalyst TiO2 anatase phase with a concentration of 1 kg/m³ was the most efficient condition, presenting full color removal for the methylene blue and 71% for the sifted textile effluent.
Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling
Authors: Xie Xinhua , Huang Xiaojia , Tang Hailin , Ye Feng , Yang Lu , Guo Xiaofang , Tian Zhi , Xie Xiaofang , Peng Cheng , Xie Xiaoming 
Published: June 2018

Background:
It has been reported that diallyl disulfide (DADS) has anti-proliferative activity
in many cancers.

Objective:
The purpose of this study was to investigate the functions of DADS and the underlying
mechanisms of its effect in breast cancer stem cells (BCSCs).

Method:
Mammosphere formation assay, glucose consumption assay, lactate production assay and
mouse xenograft experiments were performed to explore the functions of DADS in BCSCs. ATPase
activity assay, western blotting and immunohistochemistry (IHC) assay were conduct to explore the
mechanisms underlying the effects of DADS in BCSCs.

Results:
The results showed that DADS suppressed cell stemness and glucose metabolism in
BCSCs. In vivo mouse xenograft experiments showed that DADS inhibited the proliferation and
metastasis of BCSCs. Then, we continued to explore the mechanisms underlying the effects of
DADS in BCSCs and found that DADS acts by targeting CD44, Pyruvate kinase M2 (PKM2) and
AMP-activated protein kinase (AMPK) signaling pathways. IHC analysis of 125 breast cancer patients’
tissues demonstrated that CD44, PKM2 and AMPK expression levels were positively correlated.
In addition, positive CD44, PKM2 and AMPK expression was associated with poor patient
overall survival (OS) and disease-free survival (DFS).

Conclusion:
In summary, DADS suppresses cell stemness, proliferation, metastasis and glucose
metabolism in BCSCs partly through the inhibition of CD44/PKM2/AMPK. DADS may be used as
a potential therapy for breast cancer treatment.
The Measurement and Mathematical Analysis of 5-Fu Release from Magnetic Polymeric Nanocapsules, following the Application of Ultrasound
Authors: Abed Ziaeddin , Khoei Samideh , Ghalandari Behafarid , Beik Jaber , Shakeri-Zadeh Ali , Ghaznavi Habib , Shiran Mohammad-Bagher 
Published: June 2018

Objective: To study the effects of ultrasound irradiation on the release profile of 5-fluorouracil (5-Fu)
loaded magnetic poly lactic co-glycolic acid (PLGA) nanocapsules. Also, the controlled drug-release behaviour
of the nanocapsules was mathematically investigated.

Methods:
The nanocapsules were synthesized, dispersed in phosphate buffered saline (PBS), transferred to a
dialysis bag, and finally, irradiated by various ultrasound parameters (1 or 3MHz; 0.3-1W/cm2; 5-10 minutes).
The release profile of the irradiated nanocapsules was recorded for 14 days. To find the in vitro drug release
mechanism in the absence and presence of various intensities of ultrasound, the obtained data were fitted in
various kinetic models for drug release.

Results:
The results demonstrated that the ultrasound speeded up the rate of drug release from the nanocapsules.
The mathematical analysis illustrated that when the ultrasound intensity is increased, the probability of controlled
release behaviour of the nanocapsules is raised. We found that drug release from the irradiated nanocapsules
follows an erosion-controlled mechanism with the decrease in the velocity of diffusion.

Conclusion:
In conclusion, to attain a controlled drug-delivery strategy in the area of cancer therapy, the drug
release profile of the nano-carriers may be well-controlled by ultrasound.
Social State Influences Memory in Novel Object Recognition Test Through Oxidative Stress Balance in Male Rats
Authors: Famitafreshi Hamidreza , Karimian Morteza 
Published: June 2018

Objective:Social isolation is associated with adverse effects on brain functions. According to previous studies, the reduction of oxidative stress improves cognitive functions. Memory performance is dependent on hippocampus and prefrontal function. The aim of this study is to show that impairment of memory in object recognition test in isolation state is accompanied by deregulation of oxidative stress balance in related areas.Methods and Materials:In this study, 14 male Sprague-Dawley rats were randomly divided into two groups as follows: social and isolation. Socialization and isolation plus one week of acclimatization occurred for fourteen days. At the end of the study, after performing behavioral test, (novel object recognition test) rats were anesthetized and sacrificed. After preparation of tissues in controlled condition, oxidative stress status in hippocampus and prefrontal cortex for Malondialdehyde (MDA), glutathione and nitrite/nitrate was assessed.Results:MDA in the hippocampus and prefrontal cortex was higher in isolated rats compared to social rats. Glutathione and nitrite/nitrate in the hippocampus and prefrontal cortex were lower in isolated rats compared to social rats. Memory performance in novel object recognition test both in short term and long term was better in social rats.Conclusion:Memory performance in novel object recognition test is influenced by social and oxidative stress status. So improving memory is possible through socialization and improvement of antioxidant status.
Using Cellulolytic Nitrogen Fixing Bacterium, Azomonas agilis for Effective Degradation of Agricultural Residues
Authors: Latt Zaw K. , Yu San S. , Kyaw Ei P. , Lynn Tin M. , Nwe May T. , Mon Wai W. , Aye Kyaw N. 
Published: June 2018

Introduction:Azomonas agilis, a nitrogen-fixing bacterium, was isolated from rhizospheric soil in central Myanmar.Methods & Materials:The nitrogen-fixing activity of this bacterium was detected by plate screening method using glucose nitrogen free mineral medium and ammonium test-kit Cellulolytic activity was screened by plat assay and detected by Dinitrosalicyclic acid method (DNS).Results & Discussion:The isolatedA. agilisgrew in media containing 3-12% of NaCl, although the growth became poor when NaCl concentrations increased. Among various carbon sources, sucrose was the best source for ammonium accumulation of this bacterium, whereas arabinose was not the suitable carbon source. Although the nitrogen-fixing activity ofA. agiliswas highest after one week incubation, cellulase enzyme production was highest after 2-3 days of incubation. It was observed that cellulase enzyme activity ofA. agilisfor cellulose and sodium carboxymethyl cellulose (CMC) was almost the same. Three agricultural wastes were used to detect the cellulase enzyme activity ofA. agilis, cellulase activity was better on filter paper as a substrate when compared to rice-straw and sawdust.Conclusion:So, the isolatedA. agilishas high potential as an effective bacterial strain to use in sustainable agriculture and degradation of some agricultural residues.