bluuebunny/crossref_metadata_2025_split huggingface dataset:
Earthquakes and Tremor Linked to Seamount Subduction During Shallow Slow Slip at the Hikurangi Margin, New Zealand
Authors: Todd Erin K. , Schwartz Susan Y. , Mochizuki Kimihiro , Wallace Laura M. , Sheehan Anne F. , Webb Spahr C. , Williams Charles A. , Nakai Jenny , Yarce Jefferson , Fry Bill , Henrys Stuart , Ito Yoshihiro 
Published: July 2018

AbstractShallow slow slip events have been well documented offshore Gisborne at the northern Hikurangi subduction margin, New Zealand, and are associated with tectonic tremor downdip of the slow slip patch and increases in local microseismicity. Tremor and seismicity on the shallow subduction interface are often poorly resolved due to their distance from land‐based seismic and geodetic networks. To address this shortcoming, the Hikurangi Ocean Bottom Investigation of Tremor and Slow Slip experiment deployed 24 absolute pressure gauges and 15 ocean bottom seismometers on the seafloor above the Gisborne slow slip patch to investigate the spatial and temporal extent of slow slip and associated tremor and earthquake activity. We present a detailed spatiotemporal analysis of the seismic signatures of various interplate slip processes associated with the September/October 2014 Gisborne slow slip event. Tectonic tremor begins toward the end and continues after the geodetically constrained slow slip event and is localized in the vicinity of two subducted seamounts within and updip of the slow slip patch. The subsequent, rather than synchronous occurrence of tremor suggests that tremor may be triggered by stress changes induced by slow slip. However, Coulomb failure stress change models based on the slow slip distribution fail to predict the location of tremor, suggesting that seamount subduction plays a dominant role in the stress state of the shallow megathrust. This and the observed interplay of seismic and aseismic interplate slip processes imply that stress changes from slow slip play a secondary role in the distribution of associated microseismicity.
Interannual and Secular Variability of Larvae of Mesopelagic and Forage Fishes in the Southern California Current System
Authors: McClatchie Sam , Gao Jin , Drenkard Elizabeth J. , Thompson Andrew R. , Watson William , Ciannelli Lorenzo , Bograd Steven J. , Thorson James T. 
Published: July 2018

AbstractWe used univariate and multivariate spatiotemporal delta models to quantify changes in the distribution of ichthyoplankton in the southern California Current System from 1951 to 2016. We focus on mesopelagic species, because they are most abundant, and on northern anchovy (Engraulis mordax), Pacific sardine (Sardinops sagax), and Pacific hake (Merluccius productus), because they are important commercial and forage fish species. Univariate models indicated that changes in the relative abundance, area occupied, center of gravity, and spatiotemporal variability of numerically dominant warm‐water and cool‐water‐associated mesopelagic ichthyoplankton show strong species‐specific differences. Multivariate models revealed that the warm‐water‐associated mesopelagic assemblage exhibits an increasing, nonmonotonic, secular trend of increasing relative abundance underlying interannual variability, suggesting a tropicalization of the southern California Current System. In contrast, the cool‐water‐associated mesopelagic assemblage shows mainly interannual variability, with little secular trend over the 65‐year period. Correlation matrices of the modeled ichthyoplankton densities showed that the spatial distributions of northern anchovy and Pacific hake are highly correlated with cool‐water mesopelagic ichthyoplankton, but Pacific sardine is spatially correlated with both warm‐ and cool‐water‐associated mesopelagic species. Declines of adult sardine, anchovy, and hake are occurring concurrently with tropicalization of the southern California Current System. The most parsimonious explanation for tropicalization of the ichthyoplankton is increased presence of Pacific Equatorial‐influenced Water in the inshore southern California region.
Surface Salinity Balance in the Tropical Pacific Off Mexico
Authors: Portela Esther , Beier Emilio , Barton Eric D. , Sánchez‐Velasco Laura 
Published: July 2018

AbstractA simplified analytical model was used to solve the salinity balance equation and study the relative contributions of freshwater flux and salt advection to the salinity tendency between the Gulf of Tehuantepec and Cabo Corrientes (14–22°N). The model used climatological mixed‐layer salinity, satellite‐derived geostrophic velocity and evaporation minus precipitation data in a four‐domain scheme. The mean circulation derived from the model largely coincides with previous reports and suggests that, in the steady state, the Mexican Coastal Current is decoupled from the Tehuantepec region. The analysis of the time‐dependent variability showed that the salt advection can be largely explained by the annual variations of the alongshore velocity (corresponding with the Mexican Coastal Current) and an average salinity. At the seasonal scale, the salt advection and the freshwater flux have similar contributions to the resulting salinity tendency. Near Tehuantepec, due to a local salinity regime, the analytical model does not represent well the observations, while in Manzanillo and Zihuatanejo the agreement between the model and the observations is good in both amplitude and phase. The accuracy of the model in representing the observations is improved in the first third of the year by inclusion of the semiannual scale and the nonlinear processes in the equation of salt advection.
Versatility of ARD1/NAA10-mediated protein lysine acetylation
Authors: Vo Tam Thuy Lu , Jeong Chul-Ho , Lee Sooyeun , Kim Kyu-Won , Ha Eunyoung , Seo Ji Hae 
Published: July 2018

AbstractPost-translational modifications (PTMs) are chemical alterations that occur in proteins that play critical roles in various cellular functions. Lysine acetylation is an important PTM in eukaryotes, and it is catalyzed by lysine acetyltransferases (KATs). KATs transfer acetyl-coenzyme A to the internal lysine residue of substrate proteins. Arrest defective 1 (ARD1) is a member of the KAT family. Since the identification of its KAT activity 15 years ago, many studies have revealed that diverse cellular proteins are acetylated by ARD1. ARD1-mediated lysine acetylation is a key switch that regulates the enzymatic activities and biological functions of proteins and influences cell biology from development to pathology. In this review, we summarize protein lysine acetylation mediated by ARD1 and describe the biological meanings of this modification.
Multiobjective genetic training and uncertainty quantification of reactive force fields
Authors: Mishra Ankit , Hong Sungwook , Rajak Pankaj , Sheng Chunyang , Nomura Ken-ichi , Kalia Rajiv K. , Nakano Aiichiro , Vashishta Priya 
Published: July 2018

AbstractThe ReaxFF reactive force-field approach has significantly extended the applicability of reactive molecular dynamics simulations to a wide range of material properties and processes. ReaxFF parameters are commonly trained to fit a predefined set of quantum-mechanical data, but it remains uncertain how accurately the quantities of interest are described when applied to complex chemical reactions. Here, we present a dynamic approach based on multiobjective genetic algorithm for the training of ReaxFF parameters and uncertainty quantification of simulated quantities of interest. ReaxFF parameters are trained by directly fitting reactive molecular dynamics trajectories against quantum molecular dynamics trajectories on the fly, where the Pareto optimal front for the multiple quantities of interest provides an ensemble of ReaxFF models for uncertainty quantification. Our in situ multiobjective genetic algorithm workflow achieves scalability by eliminating the file I/O bottleneck using interprocess communications. The in situ multiobjective genetic algorithm workflow has been applied to high-temperature sulfidation of MoO3 by H2S precursor, which is an essential reaction step for chemical vapor deposition synthesis of MoS2 layers. Our work suggests a new reactive molecular dynamics simulation approach for far-from-equilibrium chemical processes, which quantitatively reproduces quantum molecular dynamics simulations while providing error bars.
Identification of MicroRNAs and Their Target Genes Associated with Ovarian Development in Black Tiger Shrimp (Penaeus monodon) Using High-Throughput Sequencing
Authors: Zhao Chao , Fan Sigang , Qiu Lihua 
Published: July 2018

AbstractPlenty of evidence showing that microRNAs (miRNAs) post-transcriptionally regulate gene expression and are involved in a wide range of biological processes. However, the roles of miRNAs in ovarian development process remain largely unknown in shrimp. In the present study, high-throughput sequencing of small RNAs was performed to find specific miRNAs that are involved in ovarian development process in Penaeus monodon. Two small RNA libraries were constructed from undeveloped (UNDEV group) and developed (DEV group) ovarian tissues in P. monodon. In total, 43 differentially expressed miRNAs were identified between the two groups (P ≤ 0.05, |log2 ratio| ≥1), and their expression profiles were validated by qRT-PCR. In order to further clarify the functional roles of these differentially expressed miRNAs during ovarian development process, target gene prediction was performed. In total, 4,102 target genes of 43 miRNAs were predicted, then clustered by the Kyoto Encyclopedia of Genes and Genomes (KEGG) database; only four specific pathways related to ovarian development were obtained (P < 0.05). Dual-luciferase reporter assays and integrated expression analysis were also conducted to further clarify the interaction between the miRNAs and their target mRNAs. This study provides important information about the function of miRNAs involved in ovarian developmental stages in P. monodon.
Predictive value of the maximum serum creatinine value and growth rate in acute paraquat poisoning patients
Authors: Feng Meng-Xiao , Li Yu-Ning , Ruan Wei-Shuyi , Lu Yuan-Qiang 
Published: July 2018

AbstractThis retrospective and a single-center study evaluated the prognostic value of the maximum serum creatinine value (maxCr) and the maximum serum creatinine growth rate (Vmax) after paraquat (PQ) ingestion. One hundred and seventy-one patients with PQ poisoning were treated with a uniform protocol. Demographic variables, clinical manifestations, relevant laboratory data, maxCr and Vmax of all patients were recorded and calculated. The time after PQ ingestion of maxCr and Vmax were also recorded. Vmax and MaxCr exhibited statistically significant differences between the survivor (n = 53) and death (n = 118) groups. Vmax appeared earlier in the death group than the survivor group. Regard to the receiver operating characteristic (ROC) curve analysis, Vmax had an AUC of 0.861 (95% CI, 0.801–0.921) and the optimal cut-off value of 6.21 μmol/(L·h) (sensitivity, 76.3%; specificity, 81.1%). MaxCr had an area under the curve (AUC) of 0.821 (95% CI, 0.752–0.889) and the optimal cut-off value of 225.5 µmol/L (sensitivity, 82.2%; specificity, 67.9%). The comparison of the AUC in the two parameters showed no significant difference, but Vmax appeared earlier than maxCr. Based on binary logistic regression analysis, MaxCr and Vmax both showed strong predictive powers for evaluating the prognosis of acute PQ poisoning patients.
Poultry and beef meat as potential seedbeds for antimicrobial resistant enterotoxigenic Bacillus species: a materializing epidemiological and potential severe health hazard
Authors: Osman Kamelia M. , Kappell Anthony D. , Orabi Ahmed , Al-Maary Khalid S. , Mubarak Ayman S. , Dawoud Turki M. , Hemeg Hassan A. , Moussa Ihab M. I. , Hessain Ashgan M. , Yousef Hend M. Y. , Hristova Krassimira R. 
Published: July 2018

AbstractAlthoughBacillus cereusis of particular concern in food safety and public health, the role of otherBacillusspecies was overlooked. Therefore, we investigated the presence of eight enterotoxigenic genes, a hemolytic gene and phenotypic antibiotic resistance profiles ofBacillusspecies in retail meat samples. From 255 samples, 124Bacillusisolates were recovered, 27 belonged toB.cereusand 97 were non-B.cereusspecies. Interestingly, the non-B.cereusisolates carried the virulence genes and exhibited phenotypic virulence characteristics as theB.cereus. However, correlation matrix analysis revealed theB.cereusgroup positively correlates with the presence of the geneshblA,hblC, andplc, and the detection of hemolysis (p < 0.05), while the otherBacillussp. groups are negatively correlated. Tests for antimicrobial resistance against ten antibiotics revealed extensive drug and multi-drug resistant isolates. Statistical analyses didn’t support a correlation of antibiotic resistance to tested virulence factors suggesting independence of these phenotypic markers and virulence genes. Of special interest was the isolation ofPaenibacillus alveiandGeobacillus stearothermophilusfrom the imported meat samples being the first recorded. The isolation of non-B.cereusspecies carrying enterotoxigenic genes in meat within Egypt, suggests their impact on food safety and public health and should therefore not be minimised, posing an area that requires further research.
Association between post-transplant uric acid level and renal allograft fibrosis: Analysis using Banff pathologic scores from renal biopsies
Authors: Kim Deok Gie , Kim Beom Seok , Choi Hoon Young , Lim Beom Jin , Huh Kyu Ha , Kim Myoung Soo , Jeong Hyeon Joo , Kim Yu Seun 
Published: July 2018

AbstractSeveral experimental studies implicate uric acid in renal injury and fibrosis. The objective of this study was to examine the association between uric acid level and allograft fibrosis after kidney transplantation. 241 adult patients who underwent kidney transplantation between 2003 and 2014 were divided into three groups according to the sex specific tertiles of mean uric acid level within the first post-transplant year. The renal biopsies performed during 1 to 5 post-transplant year were analyzed to compare the degree of interstitial fibrosis and tubular atrophy (IF/TA). Mean interval between kidney transplantation and biopsy was similar between groups (23.7 ± 15.3 vs. 30.0 ± 18.6 vs. 27.5 ± 18.5 months, P = 0.072). The higher tertile uric acid level was, the more advanced grade of IF/TA was shown (P = 0.001). Multivariate analysis identified uric acid tertile was independent risk factor for severe IF/TA (odds ratio [95% confidence interval] was 3.16 [1.13–8.82] for tertile 2 and 3.70 [1.25–10.93] for tertile 3, versus tertile 1, respectively). Other independent factors were estimated glomerular filtration rate at 1year post-transplant (0.80 [CI 0.65–0.98]) and biopsy-proven rejection (2.34 [1.05–5.21]). Graft survival over 10 years was significantly lower in tertile 3 (P = 0.041). The results showed that higher uric acid level after kidney transplantation was associated with more severe IF/TA.
Evidence of Systematic Triggering at Teleseismic Distances Following Large Earthquakes
Authors: O’Malley Robert T. , Mondal Debashis , Goldfinger Chris , Behrenfeld Michael J. 
Published: July 2018

AbstractEarthquakes are part of a cycle of tectonic stress buildup and release. As fault zones near the end of this seismic cycle, tipping points may be reached whereby triggering occurs and small forces result in cascading failures. The extent of this effect on global seismicity is currently unknown. Here we present evidence of ongoing triggering of earthquakes at remote distances following large source events. The earthquakes used in this study had magnitudes ≥M5.0 and the time period analyzed following large events spans three days. Earthquake occurrences display increases over baseline rates as a function of arc distance away from the epicenters. Thep-values deviate from a uniform distribution, with values for collective features commonly below 0.01. An average global forcing function of increased short term seismic risk is obtained along with an upper bound response. The highest magnitude source events trigger more events, and the average global response indicates initial increased earthquake counts followed by quiescence and recovery. Higher magnitude earthquakes also appear to be triggered more often than lower magnitude events. The region with the greatest chance of induced earthquakes following all source events is on the opposite side of the earth, within 30 degrees of the antipode.
Probing pairing symmetry in multi-band superconductors by quasiparticle interference
Authors: Dutt A. , Golubov A. A. , Efremov D. V. , Dolgov O. V. 
Published: July 2018

AbstractWe study momentum and energy dependencies of the quasiparticle interference (QPI) response function in multiband superconductors in the framework of the strong-coupling Eliashberg approach. Within an effective two-band model we study the s± and s++ symmetry cases, corresponding to opposite or equal signs of the order parameters in the bands. We demonstrate that the momentum dependence of the QPI function is strikingly different for s± and s++ symmetries of the order parameter at energies close to the small gap. At the same time, the QPI response becomes indistinguishable for both symmetries at higher energies around the large gap. This result may guide future experiments on probing pairing symmetry in iron pnictides as well as in other unconventional superconductors.
Follow-Up on the Story Goodness Index for Characterizing Discourse Deficits Following Traumatic Brain Injury
Authors: Lindsey André , Hurley Erin , Mozeiko Jennifer , Coelho Carl 
Published: July 2018

Purpose

The Story Goodness Index (SGI) is a hybrid analysis of narrative discourse combining 2 macrostructural measures: story grammar and story completeness. Initially proposed by Lê and colleagues (
Lê, Coelho, Mozeiko, & Grafman, 2011
), the SGI is intended to characterize the discourse performance of individuals with cognitive–communication disorders. In this study, the SGI was utilized to examine the discourse of 2 groups, one with closed head injuries and another with non–brain injured (NBI) peers. The intent of this study was to ascertain whether the SGI could differentiate the discourse performance of the 2 groups, as was previously reported for individuals with penetrating traumatic brain injury and an NBI comparison group (
Lê, Coelho, Mozeiko, Krueger, & Grafman, 2012
). Because of the retrospective nature of this study, the wordless visual narrative used to elicit discourse was different from the narrative used by
Lê and colleagues (2012)
.

Method
A retrospective analysis of discourse was performed on 55 individuals with a history of closed head injury and 47 NBI socioeconomically matched peers. During the initial assessment, participants were engaged in a narrative retell task. Each participant was shown a wordless picture story and then asked to retell the story to the examiner. Story narratives were reanalyzed for story grammar (organization) and completeness (critical content).

Results
A significant group difference was noted for the story grammar measure, but not for story completeness. Although the SGI plots depicted the heterogeneity in discourse performance of the 2 groups, a chi-square test of independence revealed no significant association between group membership and SGI quadrant.

Conclusions
Findings from this study were inconsistent with those of Lê and colleagues. The studies did not use identical SGI protocols; specifically, different picture stimuli were used to elicit the story retells. Therefore, this study cannot be considered a replication. The story used by Lê and colleagues was judged to be more complex, requiring more inference for story interpretation. Future studies should interpret findings within the context of the story stimuli presented.
Ruptured Abdominal Aortic Aneurysm in a Patient with Congenital Fused Pelvic Kidney: A Case Report of Emergency Endovascular Treatment
Authors: Bianchini Massoni Claudio , Azzarone Matteo , Barbarisi Danilo , Perini Paolo , Freyrie Antonio 
Published: July 2018

AbstractA 90-year-old male developed acute onset of abdominal and lumbar pain due to the rupture of an 11-cm abdominal aortic aneurysm. A congenital fused pelvic kidney perfused by three renal arteries arising from iliac axes was detected. In an emergent setting, an aorto-uni-iliac endograft was deployed through right femoral surgical access with occlusion of the upper right renal artery. An occluder device was placed in the common iliac artery above the renal artery through left femoral access. A femorofemoral crossover bypass completed the procedure. The patient developed acute renal failure, with no dialysis necessity. One-month computed tomography angiography showed procedure success.
Successful Repair of Concomitant Acute Type A Aortic Dissection and Saddle Pulmonary Embolism
Authors: Ramponi Fabio , Papps Theone , Edwards James 
Published: July 2018

AbstractPatients presenting with acute onset of chest pain require prompt diagnosis and rapid establishment of a management plan. Acute aortic dissection and acute pulmonary embolism are life-threatening emergencies that can mimic each other at presentation. Correct identification of this uncommon scenario is crucial to initiate the appropriate interventions. The authors present a unique case of concomitant acute type A aortic dissection and acute saddle pulmonary embolism; the patient underwent successful aortic repair and pulmonary embolectomy.
Haemostatic Effects of Supraphysiological Levels of Testosterone in Normal Men
Authors: Anderson R A , Ludlam C A , Wu F C W 
Published: July 2018

SummaryThe effects of exogenous testosterone on the haemostatic system were studied in a group of 32 healthy men undergoing a clinical trial of hormonal male contraception. The men received 200 mg testosterone oenanthate (TE) weekly i.m., and plasma samples were taken pretreatment, at defined time points up to 52 weeks of treatment, and 4 and 8 weeks after discontinuing TE. This dose of TE caused a 2-fold increase in trough plasma testosterone levels.TE caused a fall in plasma fibrinogen concentration after 16 weeks of treatment. This was sustained for the duration of TE treatment and recovered to pretreatment levels during the recovery phase. There was also a sustained fall in the level of C4b binding protein which showed a rebound to levels above pretreatment during recovery. Levels of antithrombin III and prothrombin fragment F1.2 rose initially during TE treatment, and levels of protein C, protein S (free) and plasminogen activator inhibitor fell, but the concentrations of these factors all returned to pretreatment levels during continued treatment. There was no change in the plasma concentrations of β-thromboglobulin, tissue plasminogen activator, protein S (total), or D-dimer. There was a sustained increase in haemoglobin concentration and haematocrit, without any change in platelet count.The observed changes were consistent with mild activation of the haemostatic system during initial treatment with testosterone. After several months the raised activation markers had returned to pretreatment levels indicating that a new equilibrium had been established which did not appear to be prothrombotic. The increase in prothrombin fragment F1.2 for the first 32 weeks, and at four weeks after discontinuation of treatment, is consistent with prolonged mildly increased prothrombinase activity. The observed substantial fall in fibrinogen is likely to have reduced, whereas the small rise in haemoglobin will have increased, the tendency to arterial thrombosis. We conclude that supraphysiological doses of testosterone do not result in a sustained marked prothrombotic state, but these results do not exclude a small change in thrombotic risk.