bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between the systemic inflammatory response index and mortality in patients with sarcopenia
Authors: Lu Yifan , Lu Chengyin , Luo Zhiqiang , Chen Pei , Xiong Hui , Li Wangyang 
Published: November 2024

Background
Sarcopenia is closely linked to inflammation; however, the association between the systemic inflammatory response index (SIRI) and mortality in patients with sarcopenia remains unclear. This study aims to explore the relationship between SIRI and mortality in sarcopenia patients.

Methods
We analyzed data from ten cycles of the National Health and Nutrition Examination Survey (NHANES) spanning 1999 to 2018, selecting 3,141 sarcopenia patients. Mortality data were obtained from the National Death Index up to December 31, 2019. Participants were divided into three groups based on the ranking of their SIRI values. The association between SIRI and mortality was assessed using Cox proportional hazards models, with smooth curve fitting employed to test the correlation. Sensitivity analyses, subgroup analyses, and interaction tests were conducted to validate the stability of the findings.

Results
A total of 101,316 individuals were included in this study. During a median follow-up of 10.4 years (minimum follow-up time of approximately 0.08 years, maximum follow-up time of 20.75 years), 667 participants died. Kaplan-Meier (KM) analysis indicated a higher risk of mortality in the SIRI Q3 group. Cox regression analysis showed a significant association between the SIRI Q3 group and all-cause mortality [HR 1.24 (95% CI: 1.05, 1.47)] and cardiovascular disease mortality [HR 1.46 (95% CI: 1.04, 2.04)]. Subgroup analysis revealed that SIRI was significantly associated with all-cause mortality across various demographic characteristics (e.g., gender, diabetes, hypertension, cardiovascular disease). Sensitivity analysis, excluding participants with cardiovascular disease, those who died within two years of follow-up, and those under 50 years old, indicated higher hazard ratios (HRs) for all-cause and cardiovascular mortality in the SIRI Q3 group.

Conclusion
This study demonstrates a significant association between SIRI and an increased risk of mortality in sarcopenia patients aged 20 years and older.
Chronic systemic inflammation predicts long-term mortality among patients with fatty liver disease: Data from the National Health and Nutrition Examination Survey 2007–2018
Authors: Pan Xinghe , Lv Jie , Liu Man , Li You , Zhang Yitong , Zhang Rui , Liu Junliang , Sun Chenglin , Guo Hongpeng 
Published: November 2024

Background
Low-grade systemic inflammation (SI) in patients with fatty liver disease (FLD) is an important hallmark of disease onset and progression. This study aims to evaluate the prognostic significance of novel SI markers in FLD.

Methods
This was a retrospective cohort study. We included adult patients with FLD with complete data and analyzed the association between chronic SI and long-term mortality in patients with FLD. Systemic immune-inflammation index (SII), pan-immune-inflammation value (PIV), and systemic inflammation response index (SIRI) were evaluated based on peripheral blood counts and FLD was determined by the Fatty Liver Index.

Results
A total of 5497 patients with FLD were included in the final analysis. SII and PIV (but not SIRI) were found to be associated with all-cause and cardiovascular mortality in univariate analysis. Multivariate Cox regression analysis and KM analysis demonstrated that SII and PIV were associated with all-cause mortality, with SII showing a nonlinear correlation in RCS. PIV (but not SII) was associated with the cardiovascular-related survival probability over time. Stratified analysis indicated that the positive correlation between SII and PIV and all-cause mortality was not altered by subgroups.

Conclusions
SII and PIV are strongly and consistently associated with all-cause mortality in patients with FLD, with PIV potentially showing a closer association with cardiovascular mortality.
Prevalence and influencing factors with knowledge, attitude, and practice toward anemia among school-going adolescent girls in rural Bangladesh
Authors: Rahman Md Jiaur , Rahman Md Moshiur , Sarker Mohammad Habibur Rahman , Kakehashi Masayuki , Tsunematsu Miwako , Ali Mohammad , Ahmed Ashir , Hawlader Mohammad Delwer Hossain , Shimpuku Yoko 
Published: November 2024

Background
Anemia is a major public health concern; however, research on anemia and its contributing variables is scarce. To address the gap, we investigated the prevalence and associated factors of anemia in school-aged adolescent girls in rural Bangladesh.

Methods
We conducted a cross-sectional study in two secondary schools at Chandpur, Bangladesh, from January to April 2022. We randomly selected 422 adolescent girls based on prevalence rates from existing research to ensure reliable estimates and a robust study representation. We performed interviews with a semi-structured questionnaire after receiving ethical permission and written informed consent. In addition, physical examination and anthropometric measurements were done, followed by blood testing to identify anemia. Blood hemoglobin was measured using a spectrophotometric method, and quality control was ensured by validated results with control samples. Univariate with multiple logistic regression was employed for analysis to find the association between anemia and all other variables that were adjusted to control the potential effect of confounding variables.

Results
The overall prevalence of anemia was 37.7% (mild- 33.8% and moderate- 3.9%). In the univariate analysis having a working mother (OR 3.84; 95% CI 1.31–11.26), undernutrition (OR 2.40; 95% CI 1.27–4.52), and irregular lunch consumption (OR 2.15; 95% CI 1.00–4.60) were associated with anemia. Conversely, being a user of a slab latrine (OR 0.61; 95% CI 0.40–0.93) and not weekly consumption of pure milk (OR 0.62; 95% CI 0.41–0.92) were negatively associated with anemia. In multivariate logistic regression analysis, associated factors for prevalent anemia were working mother [adjusted odds ratio (aOR) 7.65; 95% CI 1.97–29.50], slab latrine user (aOR 0.46; 95% CI 0.26–0.79), and irregular lunch consumption (aOR 2.92; 95% CI 1.21–7.03).

Conclusion
The prevalence of anemia among adolescent girls in rural Bangladesh remains high with undernutrition. Anemia is associated with working mothers, slab latrine users, and irregular lunch consumers within the studied population.’ Thus, policymakers may promote school-based nutritional education and lunch programs with iron supplementation and improve sanitary facilities.
COVID-19-related research data availability and quality according to the FAIR principles: A meta-research study
Authors: Sofi-Mahmudi Ahmad , Raittio Eero , Khazaei Yeganeh , Ashraf Javed , Schwendicke Falk , Uribe Sergio E. , Moher David 
Published: November 2024

Background
According to the FAIR principles (Findable, Accessible, Interoperable, and Reusable), scientific research data should be findable, accessible, interoperable, and reusable. The COVID-19 pandemic has led to massive research activities and an unprecedented number of topical publications in a short time. However, no evaluation has assessed whether this COVID-19-related research data has complied with FAIR principles (or FAIRness).

Objective
Our objective was to investigate the availability of open data in COVID-19-related research and to assess compliance with FAIRness.

Methods
We conducted a comprehensive search and retrieved all open-access articles related to COVID-19 from journals indexed in PubMed, available in the Europe PubMed Central database, published from January 2020 through June 2023, using the metareadr package. Using rtransparent, a validated automated tool, we identified articles with links to their raw data hosted in a public repository. We then screened the link and included those repositories that included data specifically for their pertaining paper. Subsequently, we automatically assessed the adherence of the repositories to the FAIR principles using FAIRsFAIR Research Data Object Assessment Service (F-UJI) and rfuji package. The FAIR scores ranged from 1–22 and had four components. We reported descriptive analysis for each article type, journal category, and repository. We used linear regression models to find the most influential factors on the FAIRness of data.

Results
5,700 URLs were included in the final analysis, sharing their data in a general-purpose repository. The mean (standard deviation, SD) level of compliance with FAIR metrics was 9.4 (4.88). The percentages of moderate or advanced compliance were as follows: Findability: 100.0%, Accessibility: 21.5%, Interoperability: 46.7%, and Reusability: 61.3%. The overall and component-wise monthly trends were consistent over the follow-up. Reviews (9.80, SD = 5.06, n = 160), articles in dental journals (13.67, SD = 3.51, n = 3) and Harvard Dataverse (15.79, SD = 3.65, n = 244) had the highest mean FAIRness scores, whereas letters (7.83, SD = 4.30, n = 55), articles in neuroscience journals (8.16, SD = 3.73, n = 63), and those deposited in GitHub (4.50, SD = 0.13, n = 2,152) showed the lowest scores. Regression models showed that the repository was the most influential factor on FAIRness scores (R2 = 0.809).

Conclusion
This paper underscored the potential for improvement across all facets of FAIR principles, specifically emphasizing Interoperability and Reusability in the data shared within general repositories during the COVID-19 pandemic.
Enhancing the Efficiency of Piano Learning Through Self-Regulated Learning Training
Authors: Dong Suqi , Gedvilienė Genutė , Karasevičiūtė Salomėja 
Published: November 2024

Self-regulated learning (SRL) is a powerful method to enhance learning efficiency. This study explores its application in piano education, focusing on goal setting and strategy use. Involving 32 piano students from the Vytautas Magnus University (VMU), the research showed that participants practicing SRL significantly improved their technique, expression, and rhythm after 8 weeks. A counterbalancing method confirmed SRL's effectiveness over traditional learning, highlighting its practical value in piano pedagogy.
Редкие иммуноопосредованные нежелательные явления: клиническая характеристика, подходы к диагностике и лечению
Authors: Жукова Л. Г. , Пасечнюк О. С. , Польшина Н. И. , Хачатурян Э. А. , Гречухина К. С. 
Published: November 2024

Внедрение иммунотерапии позволило при ряде злокачественных опухолей (ЗНО) значимо увеличить продолжительность жизни пациентов в сравнении с «классической» химиотерапией. Способность иммунотерапевтических препаратов активировать Т-лимфоциты позволяет, с одной стороны, добиться противоопухолевого эффекта, с другой — может приводить к развитию иммуноопосредованных нежелательных явлений (иоНЯ). Наиболее распространенными иоНЯ являются эндокринные (гипо- или гипертиреоз), гастроинтестинальные (колит, гепатит) и дерматологические (зуд, сыпь) реакции. Редкие, но потенциально угрожающие жизни иоНЯ требуют особого внимания.Особое место занимает перекрестный синдром, включающий миокардит, миастению и миозит, который отличается быстрыми темпами прогрессирования и высокой летальностью. Миокардит проявляется болями в груди, одышкой и тахикардией, с повышением уровня тропонина — важного диагностического маркера. Сопутствующие миозит и миастения гравис проявляются миалгией и слабостью конечностей. Для разрешения этих иоНЯ требуется применение высоких доз глюкокортикостероидов (ГКС) и иногда плазмафереза.Среди неврологических иоНЯ особо выделяют энцефалит и синдром Гийена-Барре. Энцефалит проявляется различными общемозговыми симптомами: изменениями психического статуса, головной болью, судорогами и т. д. Синдром Гийена-Барре при этом проявляется мышечной слабостью и парестезиями. Диагностика включает люмбальную пункцию, электроэнцефалограмму и ряд лабораторных исследований. Лечение основано на высоких дозах ГКС, при резистентности к ГКС — использование ритуксимаба.Офтальмологические иоНЯ могут проявляться сухостью глаз, увеитом и невритом зрительного нерва, иногда приводя к серозной отслойке сетчатки. Для диагностики требуется доступность узкоспециализированных методов, таких как офтальмоскопия и оптическая когерентная томография. Лечение включает топические и местные инъекционные ГКС.Редкие иоНЯ подчеркивают необходимость междисциплинарного подхода в лечении ЗНО, учитывая сложности диагностики и ведения подобных пациентов. Эта проблема становится все более актуальной с расширением показаний к применению иммунотерапии, что требует разработки эффективных методов управления этими особыми и иногда фатальными осложнениями.
Что надо знать о редко встречающихся возбудителях инфекций у онкологических больных?
Authors: Петухова И. Н. , Григорьевская З. В. , Багирова Н. С. , Агинова В. В. 
Published: November 2024

Работа посвящена редко встречающимся бактериальным и грибковым возбудителям инфекций. Эти микроорганизмы создают трудности в диагностике и лечении в связи с возможными ошибками идентификации возбудителя, природной или приобретенной лекарственной резистентностью.Возбудители редких инфекций могут колонизировать больных, образовывать биопленки, персистировать в окружающей среде, передаваться от больного к больному и приводить к развитию вспышек инфекции. Они нередко ухудшают прогноз лечения онкологического больного и приводят к летальному исходу.Информация об особенностях редко встречающихся микроорганизмов и возможных подходах к их лечению позволит врачам-онкологам оказывать своевременную квалифицированную помощь подобным пациентам.
Przesłuchanie podejrzanego w postępowaniu przygotowawczym na podstawie wybranych przesłanek prawa kanonicznego
Authors: Jaszcz Adam 
Published: November 2024

Szczególnie delikatnym zadaniem ordynariusza lub hierarchy w dochodzeniu wstępnym jest zdecydowanie, czy i kiedy powiadomić o nim podejrzanego. Tym samym dopuszcza się pominięcie czynności przesłuchania, jednak się jej nie wyklucza. Zagadnienie to nie zostało jednoznacznie rozwiązane w przepisach oraz doktrynie. Autor podejmuje problem podstaw prawnokanonicznych dla tej czynności. Stawia pytanie, czy i kiedy przesłuchać podejrzanego podczas dochodzenia wstępnego? Brak jednoznacznego rozstrzygnięcia powoduje konkretne problemy praktyczne. Jak pogodzić wymóg gruntowności w zbieraniu danych podczas dochodzenia oraz możliwość nieprzesłuchania podejrzanego? Jak ustalić poczytalność rzekomego sprawcy bez interakcji między nim a osobą prowadzącą dochodzenie? W artykule wyprowadza się kanoniczną zasadność przesłuchania z konkretnych celów realizowanych podczas dochodzenia wstępnego. Autor analizuje problem ochrony dobrego imienia, obejmującą nie tylko reputację i dobrą opinię, ale również godność osobową oraz prawo do wypowiedzenia prawdy.
The Impact of Antimicrobial Proteins on Plant Defense Strategies
Authors: Vishwas Dipanshu Kumar 
Published: November 2024

Antimicrobial proteins (APs) are the short polypeptides, and have an important piece of the innate defense network present in all lifeforms, including microbes, arthropods, animals, and plants. Our literature survey revealed that APs have an inherent immunological reaction in several creatures including humans, but there has a little knowledge on how they act as defense mechanisms in plants. As a result, the goal of this study is to advancement of our understanding that how these plant peptides function as an immunological defense at the molecular level in plants. Thus, our research revealed that how the anxious message created by the biological risk is recognized by plant cells and then eventually transformed into an effective defensive action. Moreover, APs might kill pathogenic microbes, fungi, and viruses, and have capacity to promptly eradicate antibiotic-mediated multidrug-resistant infections. Further, our finding with these tiny peptides gives quick, regulated, and long-lasting immunity to a wide range of pathogenic organisms via stimulation of Ca2+ influx, reactive oxygen and nitrogen species generation, and activation of MAPK cascade for the transcription of APs genes and also plant defense hormones, assures plant survival in nature. Therefore, it may conclude that APs might be used as an admirable weapon for protecting plants from different infections, and recommends a bright future in agricultural and therapeutic studies.
ETHNOMATHEMATICS IN THE RADAP RAHAYU DANCE AND ITS IMPLEMENTATION IN MATHEMATICS LEARNING
Authors: Sabirin Muhamad , Atsnan Muh. Fajaruddin , Hilaliyah Siti 
Published: November 2024

Radap Rahayu dance is an original dance from South Kalimantan, Indonesia. This dance is a cultural heritage of Banjar, South Kalimantan. It has ethnomathematics potential that needs to be studied. The study aimed to explore the ethnomathematics aspects of the Radap Rahayu dance. The subjects of this research were Banjarmasin cultural figures and artists, dance lecturers and dance teachers The four focuses of this ethnographic research are, finding the mathematical concepts in the movement, musical instrument accompaniment, clothing, and ethnomathematics implementation of the Radap Rahayu Dance in mathematics learning. Data collection techniques using Focus Group Discussion with observation, interviews, and elaboration of the three research subjects. The data analysis technique refers to Miles and Huberman, with data validity using source triangulation. The research results show four things. First, there is a concept of counting, measurement, reflection, circles, and triangles in the Radap Rahayu dance movements/varieties. Second, there is a concept of symmetry, a circle, and an integral symbol on the musical instrument accompanying the Radap Rahayu Dance. Third, there is a concept of a triangle, symmetry, parallel lines, a circle, and dilatation in the costume of Radap Rahayu Dance. And, the implementation of the ethnomathematics aspects of the Radap Rahayu Dance in Mathematics Learning is found in the student module and Worksheets, which contain project-based activities making mathematics more meaningful and fun. Keywords: Ethnomathematics, Radap Rahayu Dance, Mathematics Learning
ANALYSIS OF UNDERGRADUATE STUDENTS' CREATIVE MATHEMATICAL THINKING ABILITIES
Authors: Br Ginting Siti Salamah , Armanto Dian , Dewi Izwita 
Published: November 2024

This research aimed to analyze undergraduate students’ mathematical creative thinking abilities (MCTA). This study employs a qualitative descriptive method, with the research subjects being Mathematics Education Study Program students. Tests and interviews were the instruments used for mathematical creative thinking ability. The results of the research show that students' mathematical creative thinking abilities vary, as many as 20% are in the low category (CCTA < 33%), 60% are in the medium category (CCTA between 33% and 67%) and 20% are in the high category (CCTA > 67 %). Understanding mathematical concepts, learning experiences, and motivation all have an impact on students creative mathematical thinking skills. It is hoped that the results of this research can be considered when designing learning that can develop students' mathematical creative thinking abilities. Keywords: analyze, mathematical creative thinking abilities, undergraduate students’
THE EFFECTIVENESS OF ETHNOMATHEMATICAL APPROACHES ON STUDENTS' MATHEMATICAL CREATIVE THINKING SKILLS IN INDONESIA: A META-ANALYSIS STUDY
Authors: Mandala Arif Sapta , Hidayah Irma Rachmah , Rahmawati Dian 
Published: November 2024

This meta-analysis study aimed to investigate the effectiveness of ethnomathematical approaches to students' mathematical creative thinking (MCT) skills in Indonesia. Twenty-two articles in the last decade were synthesised from online databases through a rigorous selection process based on inclusion and exclusion criteria. Data analysis was carried out using a meta-analysis technique of a random effect size model using Cohen's g. This study showed that mathematics learning with an ethnomathematical approach significantly improved students' mathematical creative thinking skills with an effect size of 1.247, which is relatively large. This study does not have publication bias constraints, so the results are scientifically reliable. Therefore, this study suggests that schools in Indonesia integrate an ethnomathematical approach to mathematics learning to support students' MCT skills. Further research is recommended to develop a learning model with an ethnomathematical approach focusing on enhancing students' MCT skills. Keywords: Meta-analysis, effectiveness, ethnomathematics, mathematical creative thinking
POTENSIAL HAMA PREDATOR PADA PETERNAKAN LEBAH KELULUT (Trigona itama) DI DESA BERUNTUNG JAYA KECAMATAN CEMPAKA
Authors: Anarki Herpan , Arifin Yudi Firmanul , Rachmawati Normela 
Published: November 2024

Penelitian mengenai hewan dan orgamisme yang berpotensi sebagai hama dan predator bagi lebah kelulut belum banyak ditemui. Oleh karena itu untuk mengoptimalkan produksi peternakan kelulut maka perlu di lakukan observasi mengenai predator dan hama yag ditemukan di peternakan kelulut. Penelitian ini bertujuan untuk menganalisis jenis hewan yang berpotensi sebagai predator dan hama pada peternakan lebah kelulut. Metode yang digunakan dalam mengambil data lapangan yaitu metode jelajah (Rapid Asessment) dengan radius 100 meter atau setara dengan 31.400 m2. Pengamatan dilakukan selama 7 hari dibagi kedalam 3 periode per harinya terdiri dari pagi pukul 08:00–09:00 WITA, siang pukul 12:00–13:00 WITA dan sore pukul 16:00– 17:00 WITA. Hasil penelitian ini yaitu hewan predator kelulut kelas aves ditemukan 9 jenis yaitu burung bubut besar, cabai bunga api, cabai jawa, cabai kelapa, cendet, ciung air coreng, kutilang, ranjak dan sisikat. sedangkan dari kelas Herpetofauna terdapat 5 jenis hewan yaitu bunglon jambul, cicak rumah, cicak tembok, kadal terbang, dan kongkang gading. Sedangkan dari kelas Insekta terdapat 15 jenis yaitu capung helikopter, capung badak, capung lebah garis kuning, capung sawah, capung sayap merah, jangkrik rumput, kutu pembunuh, laba-laba cyclosa, laba-laba kayu, laba-laba leucauge, laba-laba loncat, laba-laba nephilengys, laba-laba pemburu, laba-laba tetragnatha dan semut pheidole. Hewan yang teridentifikasi sebagai hama di peternakan kelulut, dari kelas aves terdapat 2 jenis yaitu burung madu kelapa dan burung madu sriganti, sedangkan dari kelas Insekta terdapat 4 jenis hewan yaitu kumbang gelap, rayap tanah, semut firaun dan semut gula.
Research on Silicone Rubber Material as a Lost Circulation Material for Antarctic Drilling
Authors: Liu Jingping , Sun Yuanwei , Sun Jinsheng , Lv Kaihe , Huang Ning , Xu Zhe , Zhang Taifeng , Li Yecheng , Zhang Guangsheng , Yi Haijiang , Hou Delin 
Published: November 2024

Summary
During Antarctic scientific drilling operations, lost circulation frequently occurs, and conventional lost circulation materials (LCMs) experience chemical degradation and a decline in mechanical performance in the region’s low temperatures, making them unable to successfully seal the leaks. This often leads to drilling accidents such as stuck drilling tools and wellbore collapse. Currently, research on LCMs for polar environments is nearly nonexistent. To address the issue of lost circulation in Antarctic drilling, we present the development of a silicone rubber LCM specifically designed for Antarctic conditions. Infrared spectroscopy and differential scanning calorimetry (DSC) demonstrate that the material maintains stable physical and chemical structures at low temperatures, while tensile testing and thermomechanical analysis (TMA) show that it retains excellent mechanical properties in low-temperature conditions. The lost circulation process was simulated using a visual lost circulation model device to replicate the low-temperature environment. The study demonstrates that the prepared silicone rubber LCM can maintain good performance at temperatures as low as −55°C in Antarctica and can efficiently and rapidly seal lost circulation channels, making it a promising material for use in Antarctic scientific drilling.