bluuebunny/crossref_metadata_2025_split huggingface dataset:
Continuous-range tunable multilayer frequency-selective surfaces using origami and inkjet printing
Authors: Nauroze Syed Abdullah , Novelino Larissa S. , Tentzeris Manos M. , Paulino Glaucio H. 
Published: December 2018

Significance
Conventional reconfigurable electrical and radio frequency (RF) structures commonly used in applications involving real-time reconfigurability in response to fast varying operational scenarios require specialized substrates or complex electrical circuits. Origami-based RF reconfigurable components and modules offer a solution featuring unique properties. First, they enable reconfigurability over continuous-state ranges (as opposed to discrete states). Second, they do not require specialized mechanical support for multilayer frequency-selective surface structures. Moreover, deployable origami-based RF structures can achieve large surface reconfigurability ratios from folded to unfolded states. Finally, these structures allow for independent control of multiple figures of merit: bandwidth, frequency of operation, and angle of incidence.
Liver-related Events in Human Immunodeficiency Virus–infected Persons With Occult Cirrhosis
Authors: Benmassaoud Amine , Nitulescu Roy , Pembroke Thomas , Halme Alex S , Ghali Peter , Deschenes Marc , Wong Philip , Klein Marina B , Sebastiani Giada 
Published: December 2018

Abstract

Background
Human immunodeficiency virus (HIV)–infected patients are at increased risk of liver-related mortality. The effect of occult cirrhosis (OcC), defined as preclinical compensated cirrhosis without any clinical findings, on liver-related events is unknown.

Methods
HIV-infected patients from 2 Canadian cohorts underwent transient elastography (TE) examination and were classified as (1) OcC (TE ≥13 kPa with no sign of cirrhosis, including absence of thrombocytopenia and signs of advanced liver disease on ultrasound or gastroscopy); (2) overt cirrhosis (OvC) (TE ≥13 kPa with signs of cirrhosis); or (3) noncirrhotic patients (TE <13 kPa). Incidence and risk factors of liver-related events were investigated through Kaplan-Meier and Cox regression analyses, respectively. We estimated monitoring rates according to screening guidelines for hepatocellular carcinoma (HCC) by OcC and OvC status.

Results
A total of 1092 HIV-infected patients (51% coinfected with hepatitis C virus) were included. Prevalence of OcC and OvC at baseline was 2.7% and 10.7%, respectively. During a median follow-up of 1.8 (interquartile range, 1.5–2.8) years, the incidence of liver-related events in noncirrhosis, OcC, and OvC was 3.4 (95% confidence interval [CI], 1.2–7.3), 34.0 (95% CI, 6.0–104.0), and 37.0 (95% CI, 17.0–69.1) per 1000 person-years, respectively. Baseline OcC (adjusted hazard ratio [aHR], 7.1 [95% CI, 1.3–38.0]) and OvC (aHR, 8.5 [95% CI, 2.8–26.0]) were independently associated with liver-related events. Monitoring rates for HCC were lower in patients with OcC (24%) compared to those with OvC (40%).

Conclusions
HIV-infected patients with OcC have a high incidence of liver-related events. Greater surveillance and earlier recognition with appropriate screening strategies are necessary for improved outcomes.
Neuron Types, Intrinsic Circuits, and Plasticity in the Inferior Colliculus
Authors: Ito Tetsufumi , Ono Munenori , Oliver Douglas L. 
Published: December 2018

Abstract
The inferior colliculus is a critical auditory center in the midbrain which virtually acts as a hub of all ascending and descending auditory information flows. Wide variety of neuronal responses to sound is found in the IC, and this variety emerges not only from the wide range of extrinsic afferent inputs, but also from the complex features of the local circuits in the IC, for example, the mosaic pattern of extrinsic fiber termination, the various neuronal types each of which compose different patterns of local connection, and the unique forms of synaptic plasticity de novo. This chapter reviews the recent progress in understanding these features, and identifies the key issues for future research.
Government and Fiscal Policy in American Economic History
Authors: Wallis John Joseph 
Published: December 2018

Abstract
Over the last 225 years, government finances in the United States have gone through three distinct stages. In the first stage, 1790–1850, state governments actively pursued policies to promote economic development and financed them from revenues from state investments. In the second, 1850–1930, local governments became the most important level of government, as measured by revenues and expenditures, and revenues shifted toward the property tax. In the third period, 1930 to the present, the national government became the most active and largest level of government, financed through income and payroll taxes, and developed an extensive network of grants to state and local governments. The chapter tracks the changes in sources of revenues and purpose of expenditures, with specific attention paid to military spending over the entire period.
Development of Lying and Cognitive Abilities
Authors: Talwar Victoria 
Published: December 2018

AbstractThe emergence and development of children’s lie-telling is closely associated with their developing cognitive abilities. Telling a lie involves complicated cognitive functions including theory-of-mind understanding and executive functioning abilities. Recent research has found that lie-telling emerges in the preschool years and children’s abilities to maintain their lies improves with age. The current chapter reviews existing literature on the development of children’s lie-telling behavior and its relation to various aspects of children’s cognitive development. It covers the work of Lewis, Stanger, and Sullivan (1989), including the well-known guessing-game experiment, where the child is left alone with temptation and the instruction not to peek. Much of Talwar, Lee, et al.’s research into three-to-seven-year-old children’s lie-telling behavior is covered; and the interaction between these studies and Theory of Mind is emphasized; this is illuminated in the account of research using child subjects with Autism Spectrum Disorder.
The History of Neuropsychology at the Boston VA
Authors: Hebben Nancy , O'Connor Margaret 
Published: December 2018

Abstract
The Veterans Administration’s response to WWII altered the fields of psychology and neurology and made it possible for the Boston VA Hospital to evolve into an environment where neuropsychology, aphasiology, and behavioral neurology could jointly flourish. Starting with Harold Goodglass, Edith Kaplan, and Norman Geschwind in the 1950s, a multi-disciplinary group of clinicians and scientists helped usher in a transition from holistic “black box” empiricist models of the brain to models that were more localizationist and modular. Under the influence of this pioneering trio of astute observers, experimentalists, and thinkers, the Boston VA became the epicenter of basic research in human cognitive and behavioral neuroscience in the world. While signaling a revolution in psychology that unified neurobiology and behavioral principles, the work done at the Boston VA established a direct link from this neuroscience of the mind to patient care, especially as it affected the veterans of the United States.
History of Neuropsychology in France
Authors: Derouesné Christian , Poirier Jacques 
Published: December 2018

Abstract
Neuropsychology in France has a long tradition, beginning with Paul Broca, Jean-Martin Charcot, and their followers who established an anatomo-clinical approach, operating primarily within the field of neurology. Henri Hécaen at Sainte Anne and François Lhermitte at the Salpêtrière in the 1950s–1960s introduced the methodology of experimental and cognitive international neuropsychology into French neuropsychology. Subsequently, most research in neuropsychology has been conducted by psychologists in collaboration with national research organizations. The development and practice of clinical neuropsychology grew in the 1980s in response to needs for the diagnosis and care of patients with Alzheimer’s disease and related disorders. In the end, advances in the science and psychology of the field of neuropsychology have resulted in its institutionalization within France, but its establishment as an independent profession and discipline remains incomplete.
History of CT Scan Studies in Aphasia—1970s to 1990s
Authors: Naeser Margaret A. , Palumbo Carole L. , Martin Paula I. 
Published: December 2018

Abstract
This chapter summarizes early computed tomography (CT) scan studies in stroke patients with aphasia from the 1970s through the 1990s. Studies took place at the Boston University Aphasia Research Center located at the Boston Veterans Affairs Medical Center. Earliest studies associated classical aphasia syndromes with lesions located in cortical language areas on CT scans. In the 1980s, studies reported that chronic aphasia could be associated with subcortical lesion only; emphasis was on lesion in white matter pathways. In the 1990s, studies showed that lesion sites on CT scans performed after 2 months poststroke could be predictive for recovery of auditory language comprehension, and meaningful nonfluent speech at 1 year poststroke. Lesion site patterns were identified for different outcome levels following specific language therapy programs. Some rare aphasia cases are included: left-handers with separate hemispheric dominance locations for speech versus comprehension in the same person; and a unilateral, word deafness case.
Infliximab trough levels are decreasing over time in patients with inflammatory bowel disease on maintenance treatment with infliximab
Authors: Orfanoudaki Eleni , Gazouli Maria , Foteinogiannopoulou Kalliopi , Theodoraki Eirini , Legaki Evangelia , Romanos Ioannis , Mouzas Ioannis , Koutroubakis Ioannis E. 
Published: December 2018

Background
Infliximab trough levels (IFX-TLs) and antibodies to infliximab (ATIs) have been suggested as useful markers for the optimization of treatment in inflammatory bowel disease (IBD). We aimed to estimate the patterns over time of IFX-TLs and ATIs in IBD patients on maintenance treatment with IFX.

Methods
Two different measurements of IFX-TLs and ATIs were performed (ELISA; Eagle BioSciences) at a 10-month interval using serum samples of consecutive patients on maintenance treatment with IFX. Certain biomarkers [hemoglobin, erythrocyte sedimentation rate, C-reactive protein (CRP), platelets, albumin] measured at the same time as well as clinical disease activity and quality of life were assessed.

Results
Among a total of 86 IBD patients under maintenance treatment with IFX, 64 [49 Crohn’s disease, 15 ulcerative colitis (UC), 42 men, mean age 44.2±15.2 years, 41 in combination therapy with immunomodulator, six in intensified dose], with two available measurements of IFX-TLs and ATIs (A and B), were included in the study. The median levels of IF-TLs were 5.07 (interquartiles range: 1.60–12.73) μg/ml in measurement A and 4.68 (1.19–7.83) μg/ml in measurement B (P<0.0001). Patients whose dose was intensified after the first measurement showed an increase in their median IFX-TLs from 1.47 to 8.5 μg/ml, whereas patients with stable IFX dose showed a significant reduction in the median IFX-TLs from 5.65 to 3.8 μg/ml (P<0.0001). In the logistic regression analysis, the decrease in IFX-TL was correlated significantly and independently with the increase in CRP [odds ratio 5.2 (1.4–19.0), P=0.01].

Conclusion
IBD patients on maintenance treatment with IFX show decreasing patterns of IFX-TLs over time associated with increasing patterns of CRP levels.
Activation of Supraspinatus and Infraspinatus Partitions and Periscapular Musculature During Rehabilitative Elastic Resistance Exercises
Authors: Joseph Ranjit , Alenabi Talia , Lulic Tea , Dickerson Clark R. 
Published: December 2018

ObjectiveThe purpose of this study was to quantify the activation of partitions within supraspinatus and infraspinatus and some periscapular muscles during four resistance exercises with elastic bands.DesignTwenty-seven right-handed healthy volunteers (age, 22.5 ± 2.7 yrs) were recruited. Intramuscular electromyography from supraspinatus (anteriorandposterior)and infraspinatus (superiorandmiddle) and surface electromyography data from the upper, middle, and lower trapezius and serratus anterior were recorded during four elastic resistance exercises (Y, T, W, L). Kinematics were recorded synchronously. Electromyography values were presented as percentage of maximal voluntary isometric contraction and compared across exercises using analysis of variance. Muscle activation ratios were also calculated.ResultsThe mean activations of all rotator cuff partitions were more than 40% maximal voluntary isometric contraction, except middle infraspinatus during the T exercise (29.3% maximal voluntary isometric contraction). Serratus anterior activity was significantly higher during the Y exercise (P< 0.008). Lower trapezius was activated more than 80% maximal voluntary isometric contraction in all four exercises with higher contributions compared with the upper trapezius.ConclusionsThe investigated exercises induced moderate to high activation in supraspinatus and infraspinatus partitions and very high activation in lower trapezius. YTWL exercises are appropriate for strengthening of some rotator cuff and periscapular muscles and for late stages of shoulder rehabilitation.
Third Molar Eruption and Hardware Fungal Infection Following Treatment of Mandibular Angle Fracture
Authors: Olenczak Jonathon Bryce , Shaffrey Ellen , Shaeffer Catherine A. , Black Jonathan S. 
Published: December 2018

Abstract
Appropriate management of lower 3rd molars is crucial to successful treatment of mandibular angle fractures. A unique case of a patient who presented for initial management of a left mandibular angle fracture with an unerupted lower 3rd molar was discussed in this study. After treatment with open reduction and internal fixation of the fracture, the lower 3rd molar erupted and the patient subsequently developed fungal osteomyelitis and hardware failure. This was successfully treated with hardware removal, maxillomandibular fixation, and combined use of an intravenous antibiotic and oral antifungal.
Ultra-Efficient Short Read Sequencing of T Cell Receptor Repertoires
Authors: Montagne Janelle M. , Zheng Xuwen Alice , Pinal-Fernandez Iago , Milisenda Jose C. , Christopher-Stine Lisa , Lloyd Thomas E. , Mammen Andrew L. , Larman H. Benjamin 
Published: December 2018

Abstract:T cell receptor (TCR) repertoire sequencing is increasingly employed to characterize adaptive immune responses. However, current TCR sequencing methodologies are complex and expensive, limiting the scale of feasible studies. Here we present Framework Region 3 AmplifiKation sequencing (FR3AK-seq), a simplified multiplex PCR-based approach for the ultra-efficient analysis of TCR complementarity determining region 3 (CDR3) repertoires. By using minimal primer sets targeting a conserved region adjacent to CDR3, undistorted amplicons are analyzed via short read, single-end sequencing. We find that FR3AK-seq is sensitive and quantitative, performing comparably to two industry standards. FR3AK-seq was utilized to quickly and inexpensively characterize the T cell infiltrates of muscle biopsies obtained from 145 patients with idiopathic inflammatory myopathies and controls. A cluster of related TCRs was identified in samples from patients with sporadic inclusion body myositis, suggesting the presence of a shared antigen-driven response. The ease and minimal cost of FR3AK-seq removes critical barriers to routine, large-scale TCR CDR3 repertoire analyses.
Noninvasive lung cancer detection via pulmonary protease profiling
Authors: Kirkpatrick Jesse , Warren Andrew D. , Tammela Tuomas , Westcott Peter M. K. , Voog Justin C. , Jacks Tyler , Bhatia Sangeeta N. 
Published: December 2018

AbstractLung cancer is the leading cause of cancer-related death and patients most commonly present with incurable metastatic disease. National guidelines recommend screening for high-risk patients with low-dose computed tomography (LDCT), but this approach has limitations including high false positive rates. Activity-based nanosensors (ABNs) detect dysregulated proteases in vivo and release a reporter to provide a urinary readout of disease activity. Here, we demonstrate the translational potential of ABNs by coupling ABN multiplexing with intrapulmonary delivery to detect early-stage lung cancer in an immunocompetent, genetically engineered mouse model (GEMM). The design of the multiplexed panel of sensors was informed by comparative transcriptomic analysis of human and mouse lung adenocarcinoma data sets and in vitro cleavage assays with recombinant candidate proteases. When employed in a Kras and Trp53 mutant lung adenocarcinoma mouse model, this approach confirmed the role of metalloproteases in lung cancer and enabled accurate early detection of disease, with 92% sensitivity and 100% specificity.
Different impacts of naturally occurring variants of the globally disseminated carbapenemase-encoding plasmid pKpQIL on the biology of host strains
Authors: Saw Howard T. H. , Webber Mark A. , Woodford Neil , Piddock Laura J. V. 
Published: December 2018

SynopsisKlebsiella-associated plasmid pKpQIL and its variant have been isolated globally. Our study aimed to determine whether a naturally occurring variant has altered host range and impacts on the fitness of different bacterial host strains. The plasmids pKpQIL-UK and pKpQIL-D2 were transferred from the original clinical isolate host strains of Klebsiella pneumoniae into Escherichia coli, Salmonella Typhimurium, Enterobacter cloacae and Serratia marcescens strains by filter-mating and conjugation frequencies determined and compared. The fitness of the resulting transconjugants was assessed by determining growth kinetics, ability to form a biofilm and persistence of the plasmids in each host was also measured. Transfer of either plasmid into Salmonella and S. marcescens was similar. However, pKpQIL-UK transferred into E. coli at a higher rate than did pKpQIL-D2; the reverse was found for E. cloacae. Both plasmids were rapidly lost from the E. coli population. Plasmid pKpQIL-UK, but not -D2, was able to persist in Salmonella. Although pKpQIL-UK imposed a greater fitness cost (inferred from an increased generation time) than -D2 on E. cloacae, it was able to persist as well as pKpQIL-D2 in this host. The pKpQIL-D2 plasmid did not confer any fitness benefit on any of the hosts under the conditions tested. Variants of the globally important pKpQIL plasmid have arisen in patients due to recombination. The impacts of the pKpQIL-UK plasmid and the -D2 variant in various Enterobacteriaceae are host-dependent. Continuing evolution of pKpQIL may alter its host range in the future.
Cloud-based improved Monte Carlo localization algorithm with robust orientation estimation for mobile robots
Authors: Li I-hsum , Wang Wei-Yen , Li Chung-Ying , Kao Jia-Zwei , Hsu Chen-Chien 
Published: December 2018

Purpose
This paper aims to demonstrate a cloud-based version of the improved Monte Carlo localization algorithm with robust orientation estimation (IMCLROE). The purpose of this system is to increase the accuracy and efficiency of indoor robot localization.

Design/methodology/approach
The cloud-based IMCLROE is constructed with a cloud–client architecture that distributes computation between servers and a client robot. The system operates in two phases: in the offline phase, two maps are built under the MapReduce framework. This framework allows parallel and even distribution of map information to a cloud database in pre-described formats. In the online phase, an Apache HBase is adopted to calculate a pose in-memory and promptly send the result to the client robot. To demonstrate the efficiency of the cloud-based IMCLROE, a two-step experiment is conducted: first, a mobile robot implemented with a non-cloud IMCLROE and a UDOO single-board computer is tested for its efficiency on pose-estimation accuracy. Then, a cloud-based IMCLROE is implemented on a cloud–client architecture to demonstrate its efficiency on both pose-estimation accuracy and computation ability.

Findings
For indoor localization, the cloud-based IMCLROE is much more effective in acquiring pose-estimation accuracy and relieving computation burden than the non-cloud system.

Originality/value
The cloud-based IMCLROE achieves efficiency of indoor localization by using three innovative strategies: firstly, with the help of orientation estimation and weight calculation (OEWC), the system can sort out the best orientation. Secondly, the system reduces computation burden with map pre-caching. Thirdly, the cloud–client architecture distributes computation between the servers and client robot. Finally, the similar energy region (SER) technique provides a high-possibility region to the system, allowing the client robot to locate itself in a short time.
A parametric study on the droplet detachment process from the ceiling under the effect of gravity
Authors: Manik Jai , Dalal Amaresh , Natarajan Ganesh 
Published: December 2018

Purpose
The purpose of this paper is to numerically investigate the effect of various parameters such as density ratio, surface wettabilities and Weber number on the droplet dripping and detachment process.

Design/methodology/approach
By using algebraic volume of fluid method, the governing equations are solved using a collocated finite volume approach in two-dimensions.

Findings
The results indicate that, for small densities of droplet, it adheres to the surface except when the surface is hydrophobic, while an increase in Weber number or presence of an additional droplet in the vicinity led to detachment.

Originality/value
The paper explores various characteristics of a droplet when two competing forces, namely, gravity and surface tension, act simultaneously. The detachment is observed for a given initial droplet size, as it becomes denser in an uniform gravitational field. The effect of droplet affinity for two droplets is also presented using the simulations.
Darcy–Forchheimer flow of nanofluid due to a curved stretching surface
Authors: Saif Rai Sajjad , Hayat T. , Ellahi R. , Muhammad Taseer , Alsaedi A. 
Published: December 2018

Purpose
The purpose of present communication is to analyze Darcy–Forchheimer flow of viscous nanofluid by curved stretchable surface. Flow in porous medium is characterized by Darcy–Forchheimer relation. Brownian diffusion and thermophoresis are considered. Convective heat and mass boundary conditions are also used at the curved stretchable surface.

Design/methodology/approach
The resulting nonlinear system is solved through shooting technique.

Findings
Skin friction coefficient is enhanced for larger porosity parameter and inertia coefficient while reverse trend is noticed for curvature parameter. Local Nusselt number is enhanced for higher Prandtl number and thermal Biot number, whereas the opposite trend is seen via curvature parameter, porosity parameter, inertia coefficient, thermophoresis parameter and Brownian motion parameter. Local Sherwood number is enhanced for Schmidt number, Brownian motion parameter and concentration Biot number, while reverse trend is noticed for curvature parameter, porosity parameter, inertia coefficient and thermophoresis parameter.

Originality/value
To the best of author’s knowledge, no such consideration has been given in the literature yet.