bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing Quality of Life Following Radical Cystectomy and Ileal Conduit for Bladder Cancer: A Study Utilizing EuroQol 5-Dimensional 3-Level
Authors: Prabhakar Richha , Prabhakar Rajat , Rao Dharmapuri R. 
Published: November 2024

Abstract

Background:
Urinary bladder cancer continues to be a significant health challenge and often requires radical cystectomy with ileal conduit (RCIC) as a primary therapeutic intervention in Stage II/III disease. The impact of this surgery on patients’ quality of life (QoL) is a critical aspect of evaluating the overall success of bladder cancer management. Therefore, we conducted a study to assess patients’ QoL following RCIC in bladder cancer patients using EuroQol 5-dimensional 3-level (EQ-5D-3L) instrument.

Materials and Methods:
In this cross-sectional study, patients of urinary bladder cancers from tertiary care centers, who underwent RCIC as a part of their curative treatment, were evaluated 1 month following surgery for QoL using the EQ-5D-3L instrument, in which patients were asked to report problems in 5 dimensions of this questionnaire.

Results:
We found that RCIC has a substantial immediate negative impact on QoL, primarily due to postoperative discomfort, anxiety/depression, and other urinary diversion-related issues. Nearly 36% of patients had some or extreme problems in 3 or more dimensions out of 5 in EQ-5D-3L.

Conclusion:
This study highlights the significance of EQ-5D-3L as a tool for evaluating QoL in patients of bladder cancer following RCIC, providing a useful framework for comprehending the multidimensional nature of their experiences. The findings emphasize that to maximize QoL, bladder cancer treatment requires individualized interventions, psychosocial support, and collaborative decision-making in bladder cancer management.
Left ventricular pacing in a young African patient with a metallic tricuspid valve and infected epicardial leads: A case report
Authors: Singhal MP , Udyavar A 
Published: November 2024

ABSTRACT
Tricuspid valve pathology is a relatively common anomaly. In patients with mechanical tricuspid valve replacement, implantation of a permanent pacemaker can be challenging due to the risk of valve damage, failure, and lead fracture associated with right ventricular endocardial leads. Epicardial leads may be an option, but they require a surgical procedure and are not preferred in patients with prior thoracotomy. This case report aims to demonstrate the safety and feasibility of left ventricular (LV) pacing via the coronary sinus (CS) in a 30-year-old young female with a mechanical tricuspid valve and infected epicardial leads. Due to the complications and contraindications of traditional approaches, Lead implantation via the CS was utilized. This method allowed for successful pacemaker implantation, demonstrating the feasibility and safety of LV pacing in such complex cases. The use of CS-guiding catheters and specialized leads facilitated effective cannulation and stable, reliable pacing, avoiding the need for further invasive surgeries.
Ubiquitination in diabetes and its complications: A perspective from bibliometrics
Authors: Xiong Li-Yuan , Zhao Wei , Hu Fa-Quan , Zhou Xue-Mei , Zheng Yu-Jiao 
Published: November 2024

BACKGROUND
Diabetes has a substantial impact on public health, highlighting the need for novel treatments. Ubiquitination, an intracellular protein modification process, is emerging as a promising strategy for regulating pathological mechanisms. We hypothesize that ubiquitination plays a critical role in the development and progression of diabetes and its complications, and that understanding these mechanisms can lead to new therapeutic approaches.
AIM
To uncover the research trends and advances in diabetes ubiquitination and its complications, we conducted a bibliometric analysis.
METHODS
Studies on ubiquitination in diabetes mellitus and its complications were retrieved from the Web of Science Core Collection. Visual mapping analysis was conducted using the CiteSpace software.
RESULTS
We gathered 791 articles published over the past 23 years, focusing on ubiquitination in diabetes and its associated complications. These articles originated from 54 countries and 386 institutions, with China as the leading contributor. Shanghai Jiao Tong University has the highest number of publications in this field. The most prominent authors contributing to this research area include Wei-Hua Zhang, with Zhang Y being the most frequently cited author. Additionally, The Journal of Biological Chemistry is noted as the most cited in this field. The predominant keywords included expression, activation, oxidative stress, phosphorylation, ubiquitination, degradation, and insulin resistance.
CONCLUSION
The role of ubiquitination in diabetes and its complications, such as diabetic nephropathy and cardiomyopathy, is a key research focus. However, these areas require further investigations.
Greenness assessment of continuous FIA-spectrophotometric method for quantitation of oxymetazoline in bulk and pharmaceutical forms
Authors: Fadhil Ghadah , A. Al-Uzri Wasan 
Published: November 2024

An accurate and cost-effective method utilizing continuous flow injection spectroscopy has been developed for analyzing oxymetazoline hydrochloride in pharmaceutical and bulk powder forms. This new method involves reacting drug in an alkaline solution with diazotized 4-chloroaniline to produce an orange dye with a maximum absorption at λmax of 483 nm. The flow injection analysis approach was extensively studied in terms of both chemical and physical characteristics to achieve high sensitivity. Within a concentration range of 50-150 μg/mL and a detection limit of 10.4 μg/mL, oxymetazoline hydrochloride follows Beer's law when the experimental variables are optimized. The method's effectiveness was confirmed by achieving high reproducibility of less than 2% (n = 5). A statistical analysis comparing the proposed method to the standard spectrophotometric technique using F and t tests shown no significant differences in accuracy and precision. Additionally, the analytical greenness assessment and the green analytical procedure index were applied to assess the method's greenness and the results demonstrated that the flow injection analysis method satisfies the criteria of green analytical methodologies.
KEY WORDS: Flow injection analysis, Diazotization reaction, 4-Chloroaniline, Oxymetazoline hydrochloride
Bull. Chem. Soc. Ethiop. 2025, 39(2), 215-226.
DOI: https://dx.doi.org/10.4314/bcse.v39i2.3
Green synthesis, characterization, antimicrobial and anti-cancer activity of silver nanoparticles using Aristolochia bracteolate plant leaf extract: experimental and theoretical calculations
Authors: Durairaju P. , Raja G. , Venkatesh G. , Govindasamy C. , S. El Newehy Ahmed , Haseena S. , Vennila P. , Balasubramaniyan S. 
Published: November 2024

Silver nanoparticles were synthesized using Aristolochia bracteolate plant extracts. The nanoparticles were subsequently studied using various techniques such as UV-Vis, FTIR, EDS, XRD, SEM, and HR-TEM analysis. MTT assays have been utilized to determine the cytotoxicity of green synthesized silver nanoparticles at concentrations ranging from 2.5 to 15 μg. The Ab-AgNPs exhibited effective cytotoxic activity against MCF-7. Anticancer activity studies revealed that Ab-AgNps produced comparable good results for standard cancer drugs. Ab-AgNPs are used for evaluating their antibacterial effectiveness against pathogenic gram-positive and gram-negative bacteria. Aristolochic acid (AA1) and Aristolochic acid (AA2) are the major phytoconstituents in the Aristolochia bracteolate. The current study reports theoretical investigations of aristolochic acids (AA1 and AA2) as well as silver nanocages aristolochic acids using density functional theory. Furthermore, the silver-doped with Aristolochic acids (AA1 and AA2) was subjected and examined their of breast cancer activity using molecular docking analysis.
KEY WORDS: Aristolochia bracteolate, Silver nanoparticles, Transmission electron microscopy, Docking, Anti cancer active
Bull. Chem. Soc. Ethiop. 2025, 39(2), 271-286.
DOI: https://dx.doi.org/10.4314/bcse.v39i2.7
Assessment RP1359 Lactiplantibacillus Plantarum (Previously Lactobacillus Plantarum) DSM 19457
Authors:   Food Standards Agency,   Food Standards Scotland
Published: November 2024

The Food Standards Agency and Food Standards Scotland (FSA/FSS) have reviewed an assessment of application RP 1359 for the renewal of authorisation of Lactiplantibacillus plantarum DSM 19457 (previously Lactobacillus plantarum) for its use as a technological additive, functional group of silage additive, in all animal species. This feed additive application has been made to renew the authorisation in Great Britain (GB) as it is 10 years since the product was authorised and placed on the market in the EU. The same product and uses have been authorised in multiple other countries as the information and data demonstrate the regulatory criteria are met. This feed additive had its application for renewal of authorisation assessed by the European Food Safety Authority (EFSA), which was published in 2022. FSA/FSS have reviewed the information available, including the EFSA renewal opinion1 and confirmed that Lactiplantibacillus plantarum DSM 19457, as described in this application, is unlikely to have any adverse effects on human or animal health or the environment in the context of its intended uses in GB.
Assessment RP1527 Lactiplantibacillus Plantarum (Formerly Lactobacillus Plantarum) NCIMB 30083
Authors:   Food Standards Agency,   Food Standards Scotland
Published: November 2024

The Food Standards Agency and Food Standards Scotland (FSA/FSS) have reviewed an assessment of application RP1527 for the renewal of authorisation of Lactiplantibacillus plantarum NCIMB 30083 for its use as a technological additive, functional group of silage additive, in all animal species. This feed additive application has been made to renew the authorisation in Great Britain (GB) as it is 10 years since the product was authorised and placed on the market in the EU. The same product and uses have been authorised in multiple other countries as the information and data demonstrate the regulatory criteria are met. This feed additive had its application for renewal of authorisation assessed by the European Food Safety Authority (EFSA), which was published in 2023. FSA/FSS have reviewed the information available, including the EFSA renewal opinion1 and confirmed that Lactiplantibacillus plantarum NCIMB 30083, as described in this application, is unlikely to have any adverse effects on human or animal health or the environment in the context of its intended uses in GB.
Social Responsibility and Sustainable Development Goals: The Case of Teachers in Christian-Protestant Schools
Authors: Severino-González Pedro , Navarrete-Robles Catalina , Caqueo-Quenaya Benjamín , Sarmiento-Peralta Giusseppe , Dote-Pardo Jairo , Rebolledo-Aburto Guipsy 
Published: November 2024

Objective: The objective of this study is to explore the perception of primary and secondary school teachers on social responsibility strategies from the SDGs in Protestant establishments.

Theoretical framework: The contributions of the theory of social responsibility and the principles of sustainable development are used. In addition, the focus is on the challenges posed by the SDGs in Christian-Protestant education.

Method: The study considers an exploratory design. A quantitative instrument was applied to a non-probabilistic sample composed of primary and secondary school teachers from Protestant institutions in Chile. Descriptive statistics, measures of central tendency, internal consistency coefficients were determined and statistically significant differences were examined.

Results and Discussion: The complementarity that the principles of confessional and Protestant education have with respect to the values of social responsibility is evident. The sociodemographic characteristics of teachers have implications in the perception of social responsibility strategies. Differences were found according to sex, university, postgraduate and position.

Research implications: Teachers, managers and leaders, for the implementation of institutional strategies and, at the same time, for the design of public policies that improve social well-being through the values of SR and the SDGs, can use the results of this study.

Conclusions: Protestant-inspired primary and secondary education institutions must promote liberty, empathy, respect, citizenship, dignity, solidarity and care for the environment. All of the above is consistent with the principles of the SDGs and the values of social responsibility.

Originality/Value: The literature is not conclusive regarding strategies that can contribute to the needs of the population. In this sense, the application of SR and SDG actions are significant for the well-being of the population. This analysis demonstrates the need that society has regarding education in values. This includes the development of institutional strategies that are congruent with the Christian faith and consistent with the demands of a globalized society.
Competency Development of Cross Border Transportation: A Case of Nong Khai Border
Authors: Ayuthaya Varangkoon Issaragura Na , Singhdong Putthiwat , Weerapong Prin 
Published: November 2024

Objectives: This research focuses on enhancing cross-border trade between Thailand and Lao PDR, specifically emphasizing Nong Khai Province—a crucial border region for economic connectivity and trade along the Mekong River. Nong Khai’s strategic location, near the Lao capital Vientiane and its role as a central hub in the North-South Economic Corridor (NSEC) and Eastern Economic Corridor (EEC), contributes significantly to regional trade and investment cooperation.

Theoretical framework: The study develops a prototype intelligent cross-border freight vehicle management system to address existing transportation challenges. The system utilizes RFID sensor technology integrated into a mobile application for real-time tracking and status notification of freight vehicles.

Methods: Data was collected through surveys with a sample of 400 logistics operators involved in transportation and distribution.

Results and Discussion: The study’s structural equation model, which evaluates factors influencing cross-border transportation efficiency at the Nong Khai checkpoint, demonstrated a strong fit with empirical data. The model fit indicators were statistically significant (Chi-Square = 20.024, df = 21, Sig. = 0.520, CMIN/df = 0.954, CFI = 1.00, NFI = 0.997, GFI = 0.992, AGFI = 0.967, IFI = 1.00, RMSEA = 0.00, RMR = 0.08), confirming that the model meets specified criteria.

Research Implications: Findings suggest that the intelligent transport system prototype could substantially improve process control and operational efficiency, supporting the expansion of border trade in Nong Khai and contributing to economic growth in the region.

Originality/Value: To enhance the safety and efficiency of logistics operations at a low cost.
Development of a Halal-Labelled Vaccine Purchasing Behavior Model: A Study on the Halal Lifestyle of Muslim Consumers and Sustainable Development Goals (Sdgs) in Indonesia
Authors: Nugroho Arif Julianto Sri , Santoso Gunawan Budi , Herawati Nanik 
Published: November 2024

Objective: This study tested the dependent variable of halal-labelled vaccine purchasing behavior influenced by three independent variables, namely vaccine efficacy beliefs, knowledge of halal vaccines and halal labelling through one moderating variable of religiosity.
Theoretical Framework: This research develops the Grand-Theory Planned Behavior model by modifying the attitude variable and adding the moderating variable of religiosity.

Method: Quantitative survey research design. The sampling technique was carried out by purposive sampling. Respondents were taken as a sample of adult consumers who had consumed the halal-labelled Flu-Bio, CoronaVac and Vac2Bio vaccines in the Soloraya area, totaling 200 respondents. Quantitative model testing was carried out using the Structural Equation Model. The model testing stages include the validity and reliability tests of indicators, descriptive tests of respondents, inferential statistical tests, classical assumption tests and tests of multi-group moderator variables. Testing the moderating variables used the statistical program tool of AMOS 21 software

Results and Discussion: It was found that there was a direct influence of vaccine efficacy beliefs, knowledge of halal vaccines and halal label on purchasing behavior. The moderating variable test of perceived religiosity was unable to strengthen the antecedents of purchasing behavior

Research Implications: It is hoped that this research will be able to increase the positive attitude of the Indonesian people towards the status of halal-labelled vaccines. Strengthening the status and lifestyle of consuming halal-labelled vaccines can improve the quality of Indonesian people's health status towards Indonesia's Golden Generation 2045 and the Sustainable Development Goals (SDGs)

Originality/Value: This research has the urgency of being able to provide answers for academics and marketers of halal-labelled products in developing a consumer behavior model for the halal community lifestyle in Indonesia. This research can be used as a marketing strategy to reduce the doubts of the Muslim community in Indonesia regarding the halalness of vaccines.
THE IMPACT OF COMPASSIONATE CARE ON PATIENT SATISFACTION WITH THE CARE PROVIDED
Authors: Le Thi Thao Hien , Lam Hoai Phuong , Le Thi Kim Phung 
Published: November 2024

Background: Assessment of quality of nursing care and patient satisfaction is limited, lacking appropriate assessment tools and patient-centered care programs that prioritize dedication in care. This study aimed to address this gap by exploring factors associated with patient satisfaction with quality of nursing care and compassionate care. Objectives: This study investigated the relationship between quality of nursing care, compassionate care, and patient satisfaction. It identifies key factors that contribute to patient satisfaction, allowing nursing managers to develop a targeted model that enhances the quality of care and improves the patient experience. Research Subjects: The study involved 266 patients hospitalized for a minimum of 72 hours at hospital in Vietnam, selected from the General Internal Medicine and General Surgery departments. Research Results: Overall patient satisfaction ratings for nursing care, quality of nursing care, and compassionate care were positive, with mean scores of 3.54 ± 0.69, 3.46 ± 0.86, and 3.54 ± 0.67, respectively. A strong positive correlation was found between patient satisfaction and both the quality of nursing care (r=0.845) and compassionate care (r=0.777). The analysis shows that 72.9% of the variation in patient satisfaction can be explained by factors of quality of care such as Medical-technical competence, Identity-oriented approach, Physical-technical conditions. Compassionate care explained 61.7% of the variance in satisfaction, with meaningful connections between Patient expectation and Capable practitioner being key factors. Mediation analysis showed that quality of nursing care had a significant indirect effect on patient satisfaction through compassionate care. Conclusion: Research highlights the importance of maintaining quality of nursing care and incorporating compassionate care attributes to enhance patient satisfaction. Healthcare organizations should focus on improvement quality of nursing care and foster a culture of compassionate care to optimize patient experiences and outcomes.
ABORDAGEM DA PULPOTOMIA EM DENTES DECÍDUOS: UMA INVESTIGAÇÃO DOS MATERIAIS EMPREGADOS NESSA PRÁTICA
Authors: Cirqueira Jéssica Marques , Leonel Augusto César Leal da Silva , Campos Paulo Victor da Costa 
Published: November 2024

O objetivo deste trabalho foi apresentar as possibilidades de novos materiais empregados na pulpotomia de dentes decíduos, enfatizando os que apresentaram resultados promissores. A metodologia deste trabalho consiste numa revisão bibliográfica, mediante embasamentos teóricos de artigos publicados nos últimos dez anos, escritos na língua inglesa, portuguesa e espanhola, pelo qual, foram selecionados nos bancos de dados online Bireme, Pubmed, Lilacs, Scielo, Portal Regional BVS e Google Acadêmico. O principal resultado obtido pela dissertação deste trabalho pressupõe que a técnica de pulpotomia com o passar dos anos, ganhou uma diversidade de materiais para a realização do procedimento, devido os avanços tecnológicos que contribuem para melhores benefícios no tratamento, como também a necessidade de educação contínua e adaptação às inovações tecnológicas na odontopediatria, visando melhorias significativas nos cuidados com a saúde bucal infantil. As conclusões deste trabalho referente à abordagem da pulpotomia em dentes decíduos demonstram que os mesmos concentram-se nas implicações dos diferentes materiais utilizados neste procedimento essencial na odontopediatria. Também, conclui-se que o futuro da pulpotomia em dentes decíduos depende da continuidade das pesquisas e do desenvolvimento de novos materiais que sejam eficientes, seguros e acessíveis, garantindo tratamentos mais eficazes e seguros para a população pediátrica.
Exploring HONO production from particulate nitrate photolysis in representative regions of China: characteristics, influencing factors, and environmental implications
Authors: Li Bowen , Gao Jian , Chen Chun , Wen Liang , Zhang Yuechong , Li Junling , Zhang Yuzhe , Du Xiaohui , Zhang Kai , Wang Jiaqi 
Published: November 2024

Abstract. The production mechanism of atmospheric nitrous acid (HONO), an important precursor of the hydroxyl radical (OH), remains controversial. Few studies have explored the effects of particulate nitrate photolysis on HONO sources under different environment conditions across China. In this work, the photolysis rate constant of particulate nitrate for HONO production (JNO3--HONO) was determined through a photochemical reaction system with PM2.5 samples collected from five representative sites in China. We developed a method to correct and quantify the “shadowing effect” – potential light extinction within aerosol layers under heavy PM2.5 loading conditions on the filters – for JNO3--HONO measurements, showing that elemental carbon (EC), the dominant light-absorbing component in PM2.5, plays a dominant role in it. The corrected JNO3--HONO values varied with the sampling period and location over a wide range, from 1.6 × 10−6 to 1.96 × 10−4 s−1, with a mean (±1 SD) of 1.71 (± 2.36) × 10−5 s−1. Chemical compositions, specifically those concerning nitrate loading and organic components, affected the production of HONO through particulate nitrate photolysis: high JNO3--HONO values were generally associated with PM2.5 samples with a high organic carbon (OC) / NO3- ratio (R2 = 0.86). We suggest that the parameterization equation between JNO3--HONO and the OC / NO3- ratio established in this work can be used to estimate JNO3--HONO under different aerosol chemical conditions, thus reducing the uncertainty in exploring daytime HONO sources. This study confirms that the photolysis of particulate nitrate can be a potential daytime HONO source in rural or southern urban sites, which are characterized by PM2.5 containing high proportions of organic matter.
“¿Y a esto le llaman furia española?”. Cine y subculturas más allá del esperpento
Authors: Elduque Albert , Barreiro Mª Soliña 
Published: November 2024

Este artículo propone un estudio de Furia española (Francesc Betriu, 1975) superando la noción de esperpento y los tópicos sobre el lumpenproletariado en el cine español. Recuperando documentos de censura del AGA (Archivo General de la Administración) y revisando la versión completa del filme, se propone que este se puede entender como la aproximación a una subcultura propia para analizar cómo la cultura futbolística y mediática del tardofranquismo irrumpió en un indomable ecosistema popular como el del Barrio Chino de Barcelona.