bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing research on the determinants of Indian MNEs: the role of sub-national institutions
Authors: Nayyar Rishika 
Published: May 2018

PurposeThe purpose of this paper is to provide directions for advancing the research on determinants of outward foreign direct investment (FDI) from India.Design/methodology/approachThe paper uses literature review as a method to identify a research gap in the literature on internationalization of Indian firms.FindingsThe synthesis of the theoretical debate and empirical studies conducted in context of EMNEs, with a particular focus on India and preliminary examination of data on cross-border acquisitions as well as institutions in India lead us to argue for the consideration of institutions at sub-national level (Indian states) in examining the determinants of outward FDI from India. The paper also proposes a conceptual framework relating to the mechanism through which institutions at the state level in India affect the propensity of firms to invest overseas.Research limitations/implicationsSince the propositions are not tested empirically, the paper does not provide conclusive results.Originality/valueIn addition to providing the synthesis of the theoretical debate and empirical studies, paper is, to the best of author’s knowledge, the first one to present a conceptual framework relating institutions at sub-national level with the outward foreign direct investment from India.
How individual’s characteristics influence financial inclusion: evidence from MENAP
Authors: Shihadeh Fadi Hassan 
Published: May 2018

Purpose
This study aims to analyze the financial inclusion of individuals living in the Middle East, North African, Afghanistan and Pakistan (MENAP). It intends to show the influence of these individuals’ characteristics on financial inclusion, using the World Bank Global Findex Database 2014 for 16 countries in the region.

Design/methodology/approach
A probit model is used to examine the marginal effect of financial inclusion of the characteristics of individuals living in the MENAP region. These characteristics include gender, age, income and education. Individual characteristics that are linked to the main financial-inclusion indicators include having a formal account and formal saving and borrowing. The barriers to having a formal account, alternative borrowing sources and motivations for borrowing are also linked to the respondents’ characteristics.

Findings
The results indicate that females and the poor are less likely to be included in financial systems, while education level enhances financial inclusion. As disadvantaged people consider access to credit is important to improving their lives, the study finds that the poor are more likely to borrow for medical issues than for other needs. While Islam is the majority religion in the MENAP region, it is not considered a barrier to having a formal bank account. Furthermore, people in different income quintiles are more likely to use informal financial sources, while the educated are more likely to use formal ones.

Practical implications
The results show that policymakers in MENAP should make more of an effort to enhance financial inclusion as a way to enhance economic development in the region. Also, governments institutions, such as central banks, financial ministries and other institutions, could build on these results to enhance financial inclusion as a way toward development in the MENAP region.

Originality/value
To the author’s best knowledge, this is the first study to examine the influence of individuals’ characteristics on financial inclusion in the MENAP region.
Demonstrating the value of “library as place” with the MISO Survey
Authors: Baker Neal , Furlong Katherine , Consiglio David , Lankewicz Holbert Gentry , Milberg Craig , Reynolds Kevin , Wilson Joshua 
Published: June 2018

Purpose
The purpose of this paper is twofold. It first examines cross-institutional benchmark data about “library as place” from 99 US schools in the Measuring Information Service Outcomes (MISO) Survey (www.misosurvey.org). The data demonstrate the value of “library as place” to students in particular. Second, the paper shares case studies of how two college libraries made MISO Survey “library as place” data actionable. Lafayette College (Easton, Pennsylvania) analyzed local MISO Survey data after a renovation to validate return on investment. Earlham College (Richmond, Indiana) analyzed MISO Survey data to help secure a science library renovation and to justify an architectural study for its main library.

Design/methodology/approach
The paper begins with an analysis of “library as place” using aggregate benchmarks derived from US college and university respondents between 2012 and 2015. Specifically, the paper contrasts student and faculty perceptions of “library as place” via national benchmarks about: library services importance, satisfaction, and use (three benchmarks); hybrid online/“place-based” library services importance, satisfaction, and use (three benchmarks). Pivoting from higher education to individual, local perspectives, two case studies reveal how academic libraries used MISO Survey findings to demonstrate the value of “library as place” for renovation purposes.

Findings
The findings include that undergraduates make more frequent use than faculty of place-based services such as reference, equipment loans, and physical course reserves. Undergraduates also find most of these services more important than faculty do. Faculty makes generally more frequent use than undergraduates of online services such as library databases and the catalog. They find that these services to be more important than undergraduates do. Faculty and undergraduates use newer library discovery systems with equal frequency and find them to be equally important. Undergraduates find comfortable library spaces to be very important, and faculty considers them to be only a bit less important.

Originality/value
This is the first paper using MISO Survey data to focus on the importance and satisfaction of place-based library services involving cross-institutional comparisons for students and faculty. Previously published research using MISO Survey data have compared the use of place-based library services. This is also the first paper to offer case studies about how institutions use MISO Survey data to demonstrate the value of “library as place.”
Federalism and Tax Reform
Authors: Freebairn John 
Published: June 2018

AbstractThe form and potential contributions of cooperative federalism and the additional skills and tasks required of the public service to turn well‐known and developed tax reforms into actual reforms are evaluated. Cooperative federalism seems necessary for reforms involving state taxes and changes in the mix of taxes. Additional public sector skills and involvement in developing details of tax reform packages and their implementation, and then monitoring the outcomes, are important to raise community understanding of, and confidence in, taxation reform.
Pump Up the Volume: Making Health and Wellbeing the Centre Stage of Economic Growth
Authors: Scott Anthony 
Published: June 2018

AbstractThe aim of this article is to comment on ‘Healthier Australians’, Chapter 2 in the Productivity Commission's report Shifting the Dial. The report elevates health and wellbeing to a central role in lifting the nation's productivity. The main recommendations centre around better information in the health care system and improving the architecture of the system to ensure more decentralised decision making. If acted upon, these solid building blocks could provide significant opportunities to save lives and improve the health of the population and the wealth of the country.
Vaccination of Urological Cancer Patients With WT1 Peptide‐Pulsed Dendritic Cells in Combination With Molecular Targeted Therapy or Conventional Chemotherapy Induces Immunological and Clinical Responses
Authors: Ogasawara Masahiro , Miyashita Mamiko , Ota Shuichi 
Published: May 2018

ABSTRACTThe prognosis of metastatic or relapsed renal cell carcinoma (RCC) or bladder cancer (BC) remains poor despite the introduction of immune checkpoint blockade agents. We aimed to investigate the safety and the feasibility of a vaccination with WT1 peptide‐loaded dendritic cells (DCs) and OK‐432 adjuvant combined with molecular targeted therapy or conventional chemotherapy. Five eligible patients with metastatic or relapsed RCC and five eligible patients with BC were enrolled. No severe adverse events related to a vaccination were observed. Seven patients with RCC or non‐muscle invasive BC had durable stable disease and three other patients had disease progression after DC vaccination. DC vaccination augmented WT1 specific immunity and the reduction of regulatory T cells which might be related to clinical outcome. These results indicate that DC‐based immunotherapy combined with a molecular targeted therapy or a conventional chemotherapy is safe and feasible for patients in advanced stage of RCC or BC.
Identification of salivary proteins in Aedes togoi (Theobald) that bind to mouse immunoglobulin E
Authors: Choi Kyung‐Min , Lee Kyeong‐Yeoll , Jeon Soung‐Hoo 
Published: May 2018

AbstractMosquito saliva contains a number of immunogenic molecules that can induce allergic reactions in host animals. The oriental tiger mosquito, Aedes togoi (Theobald), feeds on both humans and animals and is also a vector of various pathogenic viruses. However, information on immunogenic antigens in the saliva of this mosquito species is scarce. In this study, we used immunohistochemical staining and confocal microscopy to determine the fine structure of the acini lobes of salivary glands of A. togoi. In addition, we identified proteins from salivary gland extracts that reacted to mouse immunoglobulin E in an immunoblot analysis. At least nine proteins, ranging in size from 10 to 145 kDa, bound to IgEs; a 33 and 57.5 kDa protein showed the strongest binding signal. Our results provide important information on the identities of potential allergens in mosquito saliva.
Extraction of chitin and chitosan from larval exuvium and whole body of edible mealworm, Tenebrio molitor
Authors: Song Yong‐Su , Kim Min‐Woo , Moon Chaeyeong , Seo Dong‐Jun , Han Yeon Soo , Jo Yong Hun , Noh Mi Young , Park Young‐Kyu , Kim Sun‐Am , Kim Young Wook , Jung Woo‐Jin 
Published: May 2018

AbstractThe purpose of this study was to investigate the production of chitin and chitosan from both the exuvium and whole body of mealworm (Tenebrio molitor) larvae. Chitin from the exuvium and whole body of T. molitor larvae was chemically extracted with acid and alkali solutions to achieve demineralization (DM) and deproteinization (DP), respectively. The average DM (%) and DP (%) on a dry weight (DW) basis was 32.56 and 73.16% from larval exuvium, and 41.68 and 91.53% from whole body, respectively. To obtain chitosan, chitin particles from the exuvium and whole body of T. molitor larva were heated at various temperatures in different concentrations of NaOH. Average chitin yields were 18.01% and 4.92% of DW from the exuvium and whole body, respectively. The relative average yield of chitosan from whole body was 3.65% of DW. On average, over 90% of chitosan derived from whole body was deacetylated. The viscosity of chitosan from whole body was ranged from 48.0 cP to 54.0 cP. The chitin content of dry and wet byproducts from whole body were 17.32% and 16.94% respectively, compared to dry weight. The chitosan contents of byproducts on a DW basis were 14.48% in dry and 13.07% in wet byproduct. These results indicate that the exuvium and whole body of T. molitor larva may serve as a source of chitin and chitosan for use in domestic animal feed.
The Ornithodolite as a tool to quantify animal space use and habitat selection: a case study with birds diving in tidal waters
Authors: COLE Emma-Louise , WAGGITT James J , HEDENSTROM Anders , PIANO Marco , HOLTON Mark D. , BÖRGER Luca , SHEPARD Emily L. C. 
Published: May 2018

AbstractAnimal‐attached technologies can be powerful means to quantify space use and behavior; however, there are also ethical implications associated with capturing and instrumenting animals. Furthermore, tagging approaches are not necessarily well‐suited for examining the movements of multiple individuals within specific, local areas of interest. Here, we assess a method of quantifying animal space use based on a modified theodolite with an inbuilt laser rangefinder. Using a database of >4200 tracks of migrating birds, we show that detection distance increases with bird body mass (range 5 g to >10 kg). The maximum distance recorded to a bird was 5500 m and measurement error was ≤5 m for targets within this distance range: a level comparable to methods such as GPS tagging. We go on to present a case study where this method was used to assess habitat selection in seabirds operating in dynamic coastal waters close to a tidal turbine. Combining positional data with outputs from a hydrographic model revealed that great cormorants (Phalacrocorax carbo) appeared to be highly selective of current characteristics in space and time, exploiting areas where mean current speeds were <0.8 m·s−1 and diving at times when turbulent energy levels were low. These birds also oriented into tidal currents during dives. Taken together, this suggests that collision risks are low for cormorants at this site, as the 2 conditions avoided by cormorants (high mean current speeds and turbulence levels) are associated with operational tidal turbines. Overall, we suggest that this modified theodolite system is well‐suited to the quantification of movement in small areas associated with particular development strategies, including sustainable energy devices.
Response to lipopolysaccharide in Octodon degus pups produces age‐related sickness behavior but does not have effects in juveniles
Authors: RAMIREZ‐OTAROLA Natalia , ESPINOZA Janyra , KALERGIS Alexis M. , SABAT Pablo 
Published: May 2018

AbstractDuring vertebrate development, the immune function is inefficient and is mainly controlled by innate defense. While there have been detailed studies of various aspects of innate immune function, the effects of this function in the growth of vertebrates is still not well known. Similarly, there is little information regarding how early endotoxin exposure would affect juvenile phenotypes, specifically in a non‐model mammal like a precocial rodent. We evaluated the response to an antigen and its cost in offspring of the rodent Octodon degus. We inoculated pups at 4 different ages (8, 15, 22 and 30 days after birth) with an antigen to determine the ontogeny and costs of the response to an endotoxin. We assessed changes in body mass, body temperature, sickness behavior and the levels of a key mediator of the inflammatory response, the cytokine interleukin‐1β. We also determined the effects of early endotoxin exposure on the resting metabolic rate of juvenile animals (i.e. 90 days after birth). The cytokine levels, body mass and body temperature were unaffected by time of inoculation and treatment. However, pups subjected to inoculation at 22 days after birth with the antigen showed reduced locomotion. Juvenile resting metabolic rate was not affected by early endotoxin exposure. These results suggest that the magnitude of O. degus responses would not change with age. We discuss whether the lack of effect of the response on body mass or body condition is caused by environmental variables or by the precocial characteristics of O. degus.
Evolution for extreme living: variation in mitochondrial cytochrome c oxidase genes correlated with elevation in pikas (genus Ochotona)
Authors: SOLARI Katherine A. , HADLY Elizabeth A. 
Published: May 2018

AbstractThe genus Ochotona (pikas) is a clade of cold‐tolerant lagomorphs that includes many high‐elevation species. Pikas offer a unique opportunity to study adaptations and potential limitations of an ecologically important mammal to high‐elevation hypoxia. We analyzed the evolution of 3 mitochondrial genes encoding the catalytic core of cytochrome c oxidase (COX) in 10 pika species occupying elevations from sea level to 5000 m. COX is an enzyme highly reliant on oxygen and essential for cell function. One amino acid property, the equilibrium constant (ionization of COOH), was found to be under selection in the overall protein complex. We observed a strong relationship between the net value change in this property and the elevation each species occupies, with higher‐elevation species having potentially more efficient proteins. We also found evidence of selection in low‐elevation species for potentially less efficient COX, perhaps trading efficiency for heat production in the absence of hypoxia. Our results suggest that different pika species may have evolved elevation‐specific COX proteins, specialization that may indicate limitations in their ability to shift their elevational ranges in response to future climate change.
Eating as a motivated behavior: modulatory effect of high fat diets on energy homeostasis, reward processing and neuroinflammation
Authors: BUTLER Michael J. , ECKEL Lisa A. 
Published: May 2018

AbstractEating is a basic motivated behavior that provides fuel for the body and supports brain function. To ensure survival, the brain's feeding circuits are tuned to monitor peripheral energy balance and promote food‐seeking behavior when energy stores are low. The brain's bias toward a positive energy state, which is necessary to ensure adequate nutrition during times of food scarcity, is evolutionarily conserved across mammalian species and is likely to drive overeating in the presence of a palatable, energy‐dense diet. Animal models of diet‐induced overeating have played a vital role in investigating how the drive to consume palatable food may override the homeostatic processes that serve to maintain energy balance. These animal models have provided valuable insights into the neurobiological mechanisms underlying homeostatic and non‐homeostatic eating, motivation and food reward, and the development of obesity and related comorbidities. Here, we provide a brief review of this literature and discuss how diet‐induced inflammation in the central nervous system impacts the neural control of food intake and regulation of body weight. The connection between diet and the immune system provides an exciting new direction for the study of ingestive behavior and the pathophysiology of obesity.
Heat shock protein family A member 6 combined with clinical characteristics for the differential diagnosis of intestinal Behçet’s disease
Authors: Feng Rui , Chao Kang , Chen Shu Ling , Sun Can Hui , Qiu Yun , Chen Bai Li , Mao Ren , He Yao , Cao Qing Hua , Xue Ling , Zeng Zhi Rong , Zhang Sheng Hong , Chen Min Hu 
Published: May 2018

OBJECTIVETo investigate the role of heat shock protein family A member 6 (HSPA6) expression alone and in combination with clinical characteristics in distinguishing intestinal Behçet’s disease (BD) from Crohn’s disease (CD) with ileocolonic involvement.METHODSPatients diagnosed with either intestinal BD or CD were enrolled. Their clinical characteristics, disease activity, laboratory test results including hypersensitive C‐reactive protein (hsCRP) and erythrocyte sedimentation rate (ESR), endoscopic, pathological and radiological features were retrospectively analyzed. Enzyme‐linked immunosorbent assay was applied to measure serum HSPA6 levels.RESULTSAmong intestinal BD patients, abdominal pain and diarrhea were the leading gastrointestinal symptoms. Submucosal lymphocyte infiltration was the most common pathological finding. Computed tomography enterography features involved number of segments of less than 4 and bowel wall thickening. Independent factors were round/ellipsoid intestinal ulcer (P < 0.001), number of ulcers ≤5 (P = 0.050), elevated ulcer margin (P = 0.019), absence of aphthous ulcer (P = 0.005), bowel wall thickening >13 mm (P < 0.001) and serum HSPA6 level >3.725 ng/mL (P = 0.008) for the differential diagnosis between intestinal BD and CD. Serum HSPA6 expression was significantly elevated in intestinal BD (0.72 ± 0.39 ng/mL) compared with CD (0.50 ± 0.24 ng/mL, P = 0.000) and healthy controls (0.38 ± 0.37 ng/mL, P = 0.000).CONCLUSIONHSPA6 in combination with clinical, radiological and pathological characteristics is useful in distinguishing intestinal BD from CD with ileocolonic involvement.
Sacred Colportage: Readers and Agency in Early Methodist Book Distribution
Authors: Snead Jennifer 
Published: May 2018

AbstractJohn Wesley saw the production and distribution of tracts, editions and abridgements as crucial to the early Methodist movement. He enlisted his itinerant preachers as colporteurs, distributing reading material from their saddlebags. Many of them wrote versions of their own lives, edited by Wesley, who encouraged their writing while insisting that he control its publication and circulation. This combination of agency and control represents an alternative model for reading and agency in the eighteenth century. This article asks how this mode of textual distribution and access can help us understand how eighteenth‐century readers experienced agency and choice.
Safety of intra‐articular steroid injections prior to arthroplasty: Best evidence selection and risk of bias considerations
Authors: Li Hu , Xing Dan , Ke Yan , Lin Jianhao 
Published: May 2018

AbstractAimSeveral systematic reviews have been performed to investigate whether intra‐articular steroid injections can increase the risk of infection in subsequent arthroplasty. However, the conclusions of these systematic reviews are discordant. The purpose of the present study was to select best evidence and consider risk of bias of these systematic reviews and to provide recommendations through the best evidence.MethodsThe systematic reviews that compared the infection rates of arthroplasty with or without previous intra‐articular steroid injection were identified. The methodological quality and risk of bias of included systematic reviews were assessed by the AMSTAR instrument and ROBIS tool, respectively. Heterogeneity information within each variable was extracted from the included studies. The Jadad algorithm was then used to determine which systematic reviews can provide the best evidence.ResultsSix systematic reviews were eligible for inclusion. The Jadad decision‐making tool suggested that two reviews with highest AMSTAR score should be selected. According to the ROBIS tool, there were three systematic reviews with low risk of bias and three with high risk of bias. As a result, two systematic reviews conducted by Charalambous et al. and Marsland et al. with highest AMSTAR scores and low risk of bias were selected as the best evidence.ConclusionsThe present study demonstrates that intra‐articular steroid injections prior to arthroplasty did not increase infection rates severely after the operation. However, the strength of recommendation is weak due to the limitations of current evidence. Further high‐quality primary studies are still required.