bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining adherence to activity monitoring devices to improve physical activity in adults with cardiovascular disease: A systematic review
Authors: Marin Tania S , Kourbelis Constance , Foote Jonathon , Newman Peter , Brown Alex , Daniel Mark , Coffee Neil T , Nicholls Stephen J , Ganesan Anand , Versace Vincent L , Beks Hannah , Haedtke Christine A , Clark Robyn A 
Published: October 2018

Background Activity monitoring devices are currently being used to facilitate and monitor physical activity. No prior review has examined adherence to the use of activity monitoring devices amongst adults with cardiovascular disease. Methods Literature from June 2012 to October 2017 was evaluated to examine the extent of adherence to any activity monitoring device used to collect objective physical activity data. Randomized control trials comparing usual care against the use of an activity monitoring device, in a community intervention for adults from any cardiovascular diagnostic group, were included. A systematic search of databases and clinical trials registers was conducted using Joanna Briggs Institute methodology. Results Of 10 eligible studies, two studies reported pedometer use and eight accelerometer use. Six studies addressed the primary outcome. Mean adherence was 59.1% (range 39.6% to 85.7%) at last follow-up. Studies lacked equal representation by gender (28.6% female) and age (range 42 to 82 years). Conclusion This review indicates that current research on activity monitoring devices may be overstated due to the variability in adherence. Results showed that physical activity tracking in women and in young adults have been understudied.
Maternal Distress and Infant Social Withdrawal (ADBB) Following Infant Cardiac Surgery for Congenital Heart Disease
Authors: Re Jennifer M. , Dean Suzanne , Mullaert Jimmy , Guedeney Antoine , Menahem Samuel 
Published: October 2018

Background: Mothers and infants are exposed to multiple stresses when cardiac surgery is required for the infant. This study reviewed infant responsiveness using a standardized objective observational measure of social withdrawal and explored its association with measures of maternal distress. Methods: Mother–infant pairs involving infants surviving early cardiac surgery were assessed when the infant was aged two months. Infant social withdrawal was measured using the Alarm Distress Baby Scale. Maternal distress was assessed using self-report measures for maternal depression (Edinburgh Postnatal Depression Scale), anxiety (Spielberger State-Trait Anxiety Scale), and parenting stress (Parenting Stress Index–Short Form). Potential associations between infant social withdrawal and maternal distress were evaluated. Results: High levels of maternal distress and infant social withdrawal were identified relative to community norms with a positive association. Such an association was not found between infant social withdrawal and the cardiac abnormality and surgery performed. Conclusion: The vulnerability of infants requiring cardiac surgery may be better understood when factors beyond their medical condition are considered. The findings suggested an association between maternal distress and infant social withdrawal, which may be consistent with mothers’ distress placing infants subjected to cardiac surgery at substantially increased risk of social withdrawal. However, it is unclear to what extent infant withdrawal may trigger maternal distress and what the interactive effects are. Further research is warranted. Trialing a mother–infant support program may be helpful in alleviating distress and improving the well-being and outcomes for these families.
Sagittal Plane Trunk Tilt Is Associated With Upper Extremity Joint Moments and Ball Velocity in Collegiate Baseball Pitchers
Authors: Solomito Matthew J. , Garibay Erin J. , Nissen Carl W. 
Published: October 2018

Background: The trunk is a major contributor to the kinetic chain during baseball pitching by helping to transfer energy from the lower limbs to produce the desired ball speed. However, most of the research detailing the trunk’s contribution to the pitch is focused on rotational timing and coronal plane lean, with little attention focused on sagittal plane positioning of the trunk. Purpose: To determine the association between sagittal plane trunk motion and elbow varus moment and ball velocity in collegiate baseball pitchers. Study Design: Descriptive laboratory study. Methods: A total of 99 collegiate pitchers were recruited for this study and underwent a comprehensive biomechanical assessment of their pitching motion using 3-dimensional motion techniques. A random-intercepts, mixed-effects regression model was used to determine whether statistically significant associations were noted between sagittal plane trunk motion and the ball velocity and elbow varus moment. Results: There were a number of significant associations between sagittal plane trunk tilt and the elbow varus moment and ball velocity. Increased forward trunk tilt at the time of ball release was associated with an increase in elbow varus moment and a small increase in ball velocity; for every 10° of increased forward trunk tilt greater than 28° at ball release, the elbow varus moment increased by 2.9 N·m ( P = .007), and the ball velocity increased by 0.7 m/s ( P = .002). Conclusion: Sagittal plane positioning of the trunk plays a role in pitching mechanics, as it can affect both pitching performance and elbow moments. The results also indicated that there is a potential optimal trunk position and range of motion during the acceleration of the pitch that could limit the stress placed on the elbow joint. Implementing proper trunk mechanics from an early age could lead to a reduction in joint moments. Clinical Relevance: The results provide evidence for coaches and trainers to emphasize the importance of proper trunk positioning through the inclusion of core strengthening and motor control in their practice and coaching sessions in an effort to reduce the moments placed on the elbow during the pitch.
Complement-mediated thrombotic microangiopathy as a link between endothelial damage and steroid-refractory GVHD
Authors: Wall Sarah A. , Zhao Qiuhong , Yearsley Martha , Blower Luke , Agyeman Akwasi , Ranganathan Parvathi , Yang Shangbin , Wu Haiwa , Bostic Matthew , Jaglowski Samantha , Brammer Jonathan E. , William Basem , Choe Hannah , Mims Alice S. , Penza Sam , Efebera Yvonne , Devine Steven , Cataland Spero , Davies Stella M. , Vasu Sumithira 
Published: October 2018

Abstract
Transplant-associated thrombotic microangiopathy (TA-TMA), a complication of hematopoietic cell transplant (HCT), is associated with significant morbidity and mortality. The pathophysiology and overlap of TA-TMA with other posttransplant complications such as graft-versus-host disease (GVHD) is poorly understood. We retrospectively identified cases of TA-TMA among patients with grade 3/4 gastrointestinal (GI) GVHD, reviewed intestinal biopsy specimens, and performed correlative testing of biomarkers associated with TA-TMA. TA-TMA was more common in patients with steroid-refractory GVHD compared with steroid-responsive GVHD (79.3% vs 42.1%; P = .001). Among patients surviving 100 days post-HCT, 1-year survival from day 100 was significantly better for patients who had not developed TA-TMA in the first 100 days (69.5% vs 36.7%; P &lt; .001). Only 1 of 7 proposed TA-TMA histology criteria (mucosal hemorrhage) differed significantly based on GVHD steroid response. In multivariable modeling, steroid-refractory GVHD was a risk factor for development of TA-TMA (hazard ratio, 3.09; 95% confidence interval, 1.68-5.67; P &lt; .001). There were no differences in complement activation at GVHD onset; however, 2 to 6 weeks later, patients with TA-TMA had higher levels of BBPlus and C5b-9, markers of alternative and terminal pathway activation (BBPlus: median, 600 vs 209.3 ng/mL; P = .0045) (C5b-9: median, 425.9 vs 258.4 ng/mL; P = .029). TA-TMA is associated with poor overall survival (OS) following HCT and may be detected early by histologic findings and may be differentiated from GVHD by measurement of alternative and terminal complement pathway activation. It is unknown whether treatment of TA-TMA will improve survival in steroid-refractory GVHD.
Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma
Authors: Bochtler Tilmann , Merz Maximilian , Hielscher Thomas , Granzow Martin , Hoffmann Korbinian , Krämer Alwin , Raab Marc-Steffen , Hillengass Jens , Seckinger Anja , Kimmich Christoph , Dittrich Tobias , Müller-Tidow Carsten , Hose Dirk , Goldschmidt Hartmut , Hegenbart Ute , Jauch Anna , Schönland Stefan O. 
Published: October 2018

Abstract
Analysis of intraclonal heterogeneity has yielded insights into the clonal evolution of hematologic malignancies. We compared the clonal and subclonal compositions of the underlying plasma cell dyscrasia in 544 systemic light chain amyloidosis (PC-AL) patients with 519 patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), or symptomatic MM; ie, PC–non-AL patients). Using interphase fluorescence in situ hybridization, subclones were stringently defined as clone size below two thirds of the largest clone and an absolute difference of ≥30%. Subclones were found less frequently in the PC-AL group, at 199 (36.6%) of 544 as compared with 267 (51.4%) of 519 in the PC–non-AL group (P &lt; .001), and were not associated with the stage of plasma cell dyscrasia in either entity. In both groups, translocation t(11;14), other immunoglobulin heavy chain translocations, and hyperdiploidy were typically found as main clones, whereas gain of 1q21 and deletions of 8p21, 13q14, and 17p13 were frequently found as subclones. There were no shifts in the subclone/main clone ratio depending on the MGUS, SMM, or MM stage of plasma cell dyscrasia. In multivariate analysis, t(11;14) was associated with lower rates of subclone formation and hyperdiploidy with higher rates. PC-AL itself lost statistical significance, demonstrating that the lower subclone frequency in AL is a reflection of its exceptionally high t(11;14) frequency. In summary, the subclone patterns in PC-AL and PC–non-AL are closely related, implying that subclone formation depends on the main cytogenetic categories and is independent of disease entity and stage.
Development of a Precise, Clinically Relevant, Digital Classification Schema for Cancer
Authors: Pecora Andrew L. , Norden Andrew D. , Hervey John , Schultz Eric V. , Gallucci Thomas L. , Rushforth Elizabeth , Goldberg Stuart L. 
Published: October 2018

Purpose Health care transactions depend on the efficiency of digital codes. The International Classification of Diseases and Related Health Problems (ICD) coding system, which is the most commonly used digital system, fails to capture the complexity of oncologic diseases. Because important prognostic information such as cancer stage and genomic markers are missing, the potential for ICD codes to define and compare patient cohorts is severely limited. A more precise, clinically relevant, digital classification schema that incorporates prognostic elements would address these needs. Methods Working with cancer disease–specific experts, a new digital classification scheme, known as the Cota Nodal Address (CNA) system, was developed. The CNA has six components that define the disease of interest and incorporate all standard-of-care prognostic and predictive markers related to the particular cancer, including patient features. Results Properly sorted into homogeneous groupings of patients with similar prognostic characteristics, the CNA system facilitated big data analytic approaches, such as evaluations of population health, identification of variation in treatment decisions, and the enablement of value-based payment models. The schema has been applied to patients with breast cancer at a large tertiary cancer care hospital and a regional community cancer care network and has facilitated the creation and application of value-based payment models. Conclusion The development and potential uses of a prognosis-based classification system are reviewed herein. Compared with ICD coding, the greater precision of the schema permits improved analyses of variance in treatment, outcomes, and costs in cancer care management.
Demographic data and fi gures derived from Estonian Iron Age graves
Authors: Allmäe Raili 
Published: October 2018

Three Iron Age cremation graves from south-eastern Estonia and four graves including cremations as well inhumations from western Estonia were analysed by osteological and palaeodemographic methods in order to estimate the age and sex composition of burial sites, and to propose some possible demographic figures and models for living communities.
The crude birth/death rate estimated on the basis of juvenility indices varied between 55.1‰ and 60.0‰ (58.5‰ on average) at Rõsna village in south-eastern Estonia in the Middle Iron Age. The birth/death rates based on juvenility indices for south eastern graves varied to a greater degree. The estimated crude birth/death rate was somewhat lower (38.9‰) at Maidla in the Late Iron Age and extremely high (92.1‰) at Maidla in the Middle Iron Age, which indicates an unsustainable community. High crude birth/death rates are also characteristic of Poanse tarand graves from the Pre-Roman Iron Age – 92.3‰ for the 1st grave and 69.6‰for the 2nd grave. Expectedly, newborn life expectancies are extremely low in both communities – 10.8 years at Poanse I and 14.4 years at Poanse II. Most likely, both Maidla I and Poanse I were unsustainable communities.
According to the main model where the given period of grave usage is 150 years, the burial grounds were most likely exploited by communities of 3–14 people. In most cases, this corresponds to one family or household. In comparison with other graves, Maidla II stone grave in western Estonia and Rõsna-Saare I barrow cemetery in south-eastern Estonia could have been used by a somewhat larger community, which may mean an extended family, a larger household or usage by two nuclear families.
Sportsanthropometric and performance parameters of elite rock ‘n’ roll dancers
Authors: Fritzsche Anna , Fritzsche Jürgen 
Published: October 2018

Rock ‘n’ roll dancing is one of the technical compositional sports. The current state of scientific knowledge on it can be described as minimal. To change this state, the first sports science survey regarding squad training was conducted under the guidance of the authors at the Austrian national rock ‘n’ roll team. The study group consisted of 26 A, B and C level athletes in the sport of rock ‘n’ roll acrobatics. The mean BMI of the male athletes with the mean age of 23.0 years was 23.3 kg/m2. The female subjects’ mean age was 19.5 years and their mean BMI 19.8 kg/m2. The bounce values of the men were as follows: squat jump (SQJ) 37.1 cm and counter- movement jump (CMJ) 41.9 cm. Men’s mean result in long jump was 256.0 cm. The women had a lower mean bounce of 25.8 cm and 27.2 cm in SQJ and CMJ respectively. Their mean length of the long jump was 204.6 cm.
The anthropometric data showed that the male subjects’ mean body height was 1.81 m and weight 76.2 kg. The BIA measurement yielded a value of 15.8% body fat. The women’s mean height was 1.64 m and percentage of passive body substance 23.5%; their mean weight was 53.4 kg. The waist/hip ratio was 0.9 in both men and women. The Broca index was 1.2% in women and 6% in men. The AKS-index reached 1.02 in men and 0.91 in women.
Data were collected to determine the one-repetition maximum (1RM) of the upper and lower extremities: lat pulldowns (m: 76.9 kg; w: 39.4 kg), rowing (m: 58.1 kg; w: 31.9 kg), bench press (m: 75.0 kg; w: 33.8 kg) and knee flexion (90°) (m: 82.1 kg; w: 44.7 kg). The result of the sit and reach test was 7.8 cm for male subjects and 16.2 cm for female athletes.
In Which Type of Healthcare Do Patients Show Greater Loyalty? (Public Sector Management vs. Public-Private Partnership)
Authors: Calero Remedios , Gallarza Martina G. 
Published: October 2018

Introduction: The present study analyses the patients behavior in a setting with different management types: public sector management and public-private partnership. More specifically, the objective is to establish in which healthcare type (hospitalization, ambulatory surgery, emergencies, outpatients consultation) do the patients show a loyal behavior when they are in different management scenarios. Material and methods: A descriptive analysis based on secondary data collected from an internal database of the Conselleria de Sanidad of the Valencian Community in Spain, a scenario with two different healthcare management types (public sector management and public-private partnership) was conducted. Results: Higher patient ows in two healthcare types (emergency and outpatient consultation); disparate growth of the patients’ net basis; partnership favors maintaining the relationship with the patient thus preventing dropout; specialization of the public-private partnership in an assistance type: ambulatory surgery. Conclusion: The obtained results identify the healthcare types with higher patients’ loyalty, as well as the extent to which the management type affects this loyalty behaviour.
Nivel de ansiedad de los pacientes antes de ingresar a la consulta odontológica
Authors: Ferreira-Gaona Marta Inés , Díaz-Reissner Clarisse Virginia , Pérez-Bejarano Nohelia María , Cueto-González Natalia Cristina , Leggio-González Tatiana Guadalupe , Cardozo-Lovera Laura Beatriz , Jiménez-Ariste Gabriela Belén , Vidal González-Zarza Álvaro , Matiauda-Lazzeri Fabiola , Ovelar-Benítez Ana Elizabeth , Aguilera-Peralta Zoraida Beatriz 
Published: October 2018

Introducción: la ansiedad dental o miedo al tratamiento odontológico es una de las di cultades más frecuentes para el profesional, esto puede tener impacto en la salud oral. El objetivo es evaluar el nivel de ansiedad de los pacientes que acudieron a las consultas en la clínica odontológica de una empresa privada de servicios odontológicos, en 2015. Materiales y métodos: estudio transversal en el que se utilizó la Escala de Ansiedad Dental de Corah Modificada (MDAS), y se interrogó sobre la ansiedad que generan los componentes de la consulta odontológica. Resultados: participaron un total de 297 adultos de los cuales 54.85% fueron varones y la mediana de edad fue 28 años. Se obtuvo un bajo número de pacientes con ansiedad extrema (7.74 %), siendo el porcentaje más elevado para la inyección de anestésico local (85.52 %). El 17.85 % obtuvo un nivel de ansiedad elevada y el 17.85 % severa. El componente de la consulta odontológica que generó mayor nivel de ansiedad fue la extracción dental con 40.40%. Conclusión: el paciente debe sentirse lo más relajado posible al ir a una consulta odontológica por lo que se necesitan charlas a los proveedores de salud dental acerca de las diferentes técnicas para disminuir la ansiedad dental del paciente.
FOUCAULT, DELEUZE E A MÁQUINA ESCOLAR: A ESCOLA COMO DISPOSITIVO DE PODER E A PRODUÇÃO DE CORPOS DÓCEIS
Authors: Galvão Bruno Abílio 
Published: October 2018

Os conceitos de “máquina abstrata” e “agenciamento” do filósofo Gilles Deleuze, elaborados a partir de seus estudos sobre Michel Foucault, nos permitem compreender as relações de poder na escola. O espaço escolar, caracterizadocomo um agenciamento, ao atualizar uma máquina abstrata, estabelece uma forma de relação entre os indivíduos fazendo funcionar uma maquinaria complexa, produzindo certo tipo de indivíduo, cujos objetivos, traçados desde a revolução industrial, perpetuam-se até hoje. Portanto, o objetivo de nosso trabalho é compreender o papel da escola na sociedade por meio do pensamento de Gilles Deleuze e Michel Foucault acerca do poder. O método utilizado é de pesquisa bibliografia referente a tais pensadores e também sobre a escola. Esse tema se torna relevante pelo fato de nos proporcionar uma postura crítica em relação, não só ao papel da escola, mas também à postura dos integrantes desse espaço.
ORIENTAÇÕES METODOLÓGICAS PARA UM ENSINO DE FILOSOFIA BASEADO EM VIRTUDES INTELECTUAIS
Authors: Rui Matheus De Lima 
Published: October 2018

Pretendo apresentar aqui a fundamentação de uma proposta metodológica para o ensino de Filosofia, a partir de insights sobre a concepção de “virtudes”, elaborados, principalmente, pela autora contemporânea Linda Zagzebski,e marginalmente por Gilbert Ryle. Meu objetivo é sustentar que a mediação entre aluno e conhecimento não ocorre de forma mágica, ou numa relação passiva do aluno frente ao conteúdo exposto, mas envolve um contexto epistemológico relacionado a um conjunto de práticas e habilidades que estimulem as virtudes intelectuais necessárias para qualquer aprendizado. Para isso, inicialmente explico o que devemos entender por metodologia de ensino, dentro da concepção teórica desenvolvida. Em seguida, esclareço algumas noções sobre o que chamamos de “conhecimento”, e sua relação com o aprendizado. Por fim, desenvolvo a ideia chave do trabalho a partir das considerações sobre virtudes intelectuais.
A EDUCAÇÃO NO TEETETO DE PLATÃO: UM ESTUDO SOBRE A EPISTEMOLOGIA DO ENSINO E DA APRENDIZAGEM
Authors: Castro Hedgar Lopes 
Published: October 2018

O presente artigo tratará da educação intelectual como temática central do Teeteto de Platão. Em uma perspectiva de ensino e aprendizagem das ideias, pretende-se apontar como a maiêutica, a arte do parir, pode transformarum homem que nada conhece ou que conhece apenas ilusões falsas em alguém que conhece verdadeiramente. O caráter da verdade das coisas é o objeto central da dialética, que procura, ademais, verificar como o homem pode descobrir, por si só, aquilo que é Uno dentro da multiplicidade de conhecimentos que possuímos, os quais podem ser considerados, na verdade, meras impressões e opiniões. Não nos situando apenas no campo delas, é necessária, sob a inspiração platônica no Teeteto, uma educação intelectual tal que possa fazer-nos alcançar o conhecimento, descobrindo, assim, a verdade. Para isso, é fundamental a arte dialética, que serve como luz à busca permanente do conhecimento.
CONSIDERAÇÕES SOBRE NORMATIVIDADE E ESCOLHA DE SENTIDO EM SARTRE
Authors: Jalil Cristina Moreira 
Published: October 2018

A realidade humana é apresentada por Sartre como liberdade e indeterminação, o que implica dizer que não podemos contar com definições ou determinações a priori, mas que, na medida em que existimos, devemos nos fazer. Tomando como ponto de partida essa concepção da condição humana de liberdade, questionamos como é possível a essa existência livre movimentar-se em um mundo repleto de regras e orientações. Assim, nesta comunicação, nos propomos tomar como base o pensamento sartreano para refletir sobre omodo como nos relacionamos com valores e demais referências de teor normativo. Sartre afirma que nenhum imperativo, regra ou moral pode determinar de modo causal nossas ações e, dessa forma, cabe a nós sermos legisladores de nós mesmos. Buscaremos apresentar o modo como isso se dá.Em tempos como o nosso, em que voltam a ganhar força e espaço movimentos e discursos moralizantes e normatizadores, que visam fixar valores, normas e verdades universais e absolutas, torna-se relevante a retomada de pensadores que, como Sartre, buscaram afirmar e resgatar nossa condição de liberdade e o caráter de agente da nossa própria história – tanto coletiva, quanto individual.
FEMINISMO E TEORIA CRÍTICA: CRUZAMENTOS ENTRE QUESTÕES DE GÊNERO E MARXISMO
Authors: Dantas Laiz Fraga 
Published: October 2018

Esse trabalho pretende tratar da relação entre o marxismo da teoria crítica e questões de gênero através do paralelo entre o texto de Marcuse, Marxismo e Feminismo, e o modelo para a teoria crítica contemporânea de Nancy Fraser. A partir da compreensão da forma como a teoria crítica tratou os elementos do marxismo na sua filosofia da primeira geração (Marcuse) e na sua versão contemporânea (Fraser), traçaremos as consequências das mudanças na assimilação do marxismo entre esses dois modelos de teoria crítica e a forma como se compreendeu a questão de gênero.