bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study of oral tranexamic acid and triple combination versus tranexamic acid through microneedling in patients of melisma
Authors: Wali Vishal , Parwani Hemangi 
Published: July 2019

<p class="abstract"><strong>Background:</strong> Melasma can be difficult to treat due to the refractory and recurrent nature of condition. The aim of this study is to compare and evaluate the efficacy of oral tranexamic acid and triple combination versus tranexamic acid through microneedling in patients of melisma.</p><p class="abstract"><strong>Methods:</strong> This is a prospective study with a sample size of 20, 10 in each treatment arm.10 patients (group-A) were given topical triple combination to apply daily at night and along with oral tranexamic acid 250 mg twice a day, while in the other arm (group-B), 10 patients were given procedural treatment of microneedling with tranexamic acid (4 mg/ml). Patients were followed up for 3 consecutive months. Clinical photograph was taken after each visit, and a modified melasma area and severity index was performed at the beginning and end of the treatment.<strong></strong></p><p class="abstract"><strong>Results:</strong> According to melasma area and severity index, improvement in group-A was 65% as compared to 33% in group-B.</p><p class="abstract"><strong>Conclusions:</strong> Triple combination is known as gold standard treatment in melasma, but because of its long term steroidal and tretinoin side effects we can consider microneedling with TXA as an adjuvant treatment.</p><p> </p>
Diagnostico de vértigo periférico para el médico de atención primaria
Authors: Ramirez Merlano Shirley , Torres Bustamante Mariana Alexandra , Sandoval Ortiz German Pablo 
Published: July 2019

Para los médicos de atención primaria, el paciente con sintomatología compatible con síndromes vestibulares constituye un desafío, debido a su amplia variedad de presentaciones y la dificultad en la diferenciación de las diversas patologías que ocasionan los síntomas. La necesidad de tener conceptos claros y actualizados sobre los mecanismos patológicos del vértigo surge en el momento de evaluar al paciente, para esto es necesario realizar un adecuado interrogatorio y un examen físico neurotológico completo que permita dilucidar un abordaje diagnóstico certero. El objetivo del presente artículo es presentar una revisión de la literatura actual, de las diferentes etiologías desencadenantes del vértigo periférico y a partir de sus características clínicas desarrollar un algoritmo diagnóstico que permita al profesional médico entender el mecanismo patológico del vértigo y proporcionar el tratamiento adecuado.
Consentimiento informado. Percepción de pacientes. Revisión documental 1995-2013
Authors: Escobar López María Teresa 
Published: July 2019

Objetivo. Revisar literatura descriptiva y analítica sobre consentimiento informado (CI), publicada entre 1995 y 2013, centrando el interés en los estudios que muestran la percepción de los pacientes en atención clínica.
Métodos. El proceso de indagación consistió en la revisión de literatura descriptiva y analítica sobre consentimiento informado, en formatos digitales y en físico, centrando el interés en los estudios que muestran la percepción de los pacientes en atención clínica. Se compiló un total de 78 documentos entre artículos científicos, trabajos de grado, libros y capítulos de libro, publicados entre los años 1995 y 2013. Con estos aspectos de contenido se elaboró una hoja de cálculo (matriz en Excel), con resumen, consideraciones teóricas, metodológicas, observaciones y conclusiones.
Resultados. Del total de documentos consultados, solamente dos estudios particularizan sobre un área de atención clínica: la oncología, y apenas algunos tratan la percepción del CI en atención clínica de pacientes. Los demás, son de teoría sobre CI, CI e investigación o se refieren al él en general y versan sobre distintos temas, teniendo en cuenta la percepción de profesionales y expertos. Finalmente, en ningún documento se mencionan posturas teóricas sobre percepción y todos los documentos refieren problemas frente a su aplicación e implementación. En todos los casos, la autonomía se entiende como una expresión de voluntad que requiere ser aplicada, lo cual es determinante para el CI.
Conclusiones. Existen pocos estudios de percepción en pacientes y en ninguno se explica qué se entiende por este concepto. Por el contrario, es generalizado en los escritos revisados, lo que evidencia problemas relacionados con la aplicación e implementación del CI.
Increased Circulating miR-10a Levels Associated with Multiple Sclerosis
Authors: Boroumand Niloofar , Eshaghiyan Amir , Behshood Parisa , Nateghi Behnaz , Emadi Farzaneh 
Published: July 2019

Background: Multiple sclerosis (MS) is an autoimmune disease that causes chronic inflammation of the central nervous system. MicroRNAs (miRNAs) are small non-coding RNAs 19–24 nucleotides long, which are differentially expressed in different tissues. The role of miRNAs in MS remains unclear.
Aim: We assessed miR-10a transcript levels in MS patients during recurrence and two months after relapse.
Materials and Methods: In this case-control study, we used real-time PCR to examine miR-10a expression in the peripheral blood mononuclear cells of 60 patients with relapsing-remitting multiple sclerosis (RRMS), 30 during recurrence and 30 two months after relapse, and 30 healthy subjects who were referred to the MS Clinic of Kashani Hospital, Isfahan Province. In silico analysis was also performed on the validated miR- 10a targets using miRTarBase.
Results: miR-10a expression was higher in RRMS patients during recurrence and two months after relapse (p < 0.0001 and p < 0.0001, respectively) than in the healthy subjects. Furthermore, in silico molecular signaling enrichment analysis identified 12 mRNAs as validated miR-10a targets.
Conclusion: The expression of miR-10a was elevated in patients with RRMS compared to healthy subjects, suggesting that miR-10a could be a potential biomarker for RRMS diagnosis.
Adenosarcoma de alto grado de endocérvix y cavidad endometrial con componente heterólogo de rabdomiosarcoma. Reporte de caso y revisión de la literatura
Authors: Frías-Sánchez Zoraida , Pantoja-Garrido Manuel , Gutiérrez-Domingo Álvaro , Jiménez-Gallardo Julián , Polo-Velasco Alfredo , Rodríguez-Jiménez Inmaculada 
Published: July 2019

Objetivo: presentar el caso de una paciente con diagnóstico de adenosarcoma de alto grado de endocérvix y de cavidad endometrial, con componente heterólogo, y hacer una revisión de la literatura con especial atención al diagnóstico y manejo terapéutico de esa patología.
Materiales y métodos: Se presenta el caso de una paciente de 31 años, que consulta al Hospital Universitario Virgen Macarena de Sevilla, institución regional de tercer nivel, por presentar sangrado genital originado por una masa polipoidea endocervical que se llevó a biopsia con resultado de un leiomiosarcoma poco diferenciado de alto grado de endocérvix. Posteriormente fue llevada a histerectomía total abdominal. En el estudio de la pieza quirúrgica el resultado fue: adenosarcoma de endocérvix y cavidad endometrial, con componente heterólogo de rabdomiosarcoma. Con los términos: “adenosarcoma”, “endocervical”, “cérvix”, “uterus”, “heterologous”, en las bases de datos Medline vía PubMed se realizó una búsqueda de artículos de revisión bibliográfica, reportes y series de casos clínicos que describían aspectos del adenosarcoma cervicouterino y del componente heterólogo de rabdomiosarcoma, en inglés y español, publicados desde 1974.
Resultados: se hallaron seis artículos correspondientes a revisiones de la literatura, reportes o series de casos, donde se describen los aspectos más importantes referentes al diagnóstico y tratamiento de esta patología.
Conclusiones: esta patología se caracteriza, en ocasiones, por un crecimiento rápido y agresivo, donde es importante el diagnóstico precoz y el tratamiento óptimo, basado en una combinación de cirugía, radioterapia y quimioterapia, aunque dada su baja prevalencia se necesitan aún más estudios para poder confirmar estos datos.
Hopf algebras and skew PBW extensions
Authors: Salcedo Plazas Luis Alfonso 
Published: July 2019

In this article we relate some Hopf algebra structures over Ore extensions and over skew PBW extensions of a Hopf algebra. These relations are illustrated with examples. We also show that Hopf Ore extensions and generalized Hopf Ore extensions are Hopf skew PBW extensions.
PENGEMBANGAN DAN PENGGUNAAN INSTRUMEN TWO-TIER MULTIPLE CHOICE PADA MATERI TERMOKIMIA UNTUK MENGUKUR KEMAMPUAN BERPIKIR KRITIS
Authors: Laksono Pandu Jati 
Published: July 2019

Penelitian ini bertujuan untuk mengembangkan instrumen tes Two-Tier Multiple Choice pada materi termokimia menjadi instrumen penilaian yang mampu mengukur keterampilan berpikir kritis. Instrumen yang dikembangkan perlu diujikan kelayakannya ditinjau dari validitas logis para ahli dan instrumen penilaian Two-Tier Multiple Choice yang dikembangkan ditinjau dari validitas empiris yaitu reliabilitas, analisis kualitas butir soal, dan analisis pengecoh yang dapat dikategorikan soal yang baik. Penelitian ini dikategorikan sebagai penelitian pengembangan. Instrumen tes yang dikembangkan adalah Two-Tier Multiple Choice pada materi termokimia untuk mengukur kemampuan berpikir kritis . Model pengembangan yang digunakan yaitu model pengembangan 4 D (four D model) oleh S. Thigarajan, Dorothy S. Semmel, dan Melvyn I. Semmel. Model pengembangan 4D terdiri atas 4 tahap utama yaitu: (1) Define (Pendefinisian), (2) Design (Perancangan), (3) Develop (Pengembangan), dan (4) Disseminate (Penyebaran). Berdasarkan hasil penelitian yang telah dilakukan kesimpulan yang didapatkan adalah Instrumen penilaian Two-tier Multiple Choice yang dikembangkan dinyatakan layak dan memenuhi kriteria sebagai suatu soal yang baik dengan hasil validitas aiken rata-rata 0,84. Instrumen penilaian Two-tier Multiple Choice yang dikembangkan dinyatakan layak ditinjau dari realibilitas tes rata-rata 0,737 yang tergolong tinggi, memiliki daya beda dengan persentase 41,67% sangat baik, 40,00% baik,18,33% cukup baik dan 0% jelek, berdasarkan tingkat kesukaran 8,33% mudah, 80,00% sedang dan 11,67% sukar, berdasarkan indeks pengecoh disimpulkan pengecoh tidak ada yang bekerja lebih baik daripada kunci jawaban dan nilai pengecoh sebagian besar lebih dari 5% dipilih sehingga dinyatakan efektif.
PENGARUH REAL LABORATORY DAN VIRTUAL LABORATORY TERHADAP KUALITAS PROSES PADA MATERI KESETIMBANGAN KIMIA
Authors: Rohmah Mawadatur , Ibnu Suhadi , Budiasih Endang 
Published: July 2019

Kesetimbangan kimia adalah salah satu materi kimia yang dianggap memiliki beberapa konsep sulit, sehingga harus disampaikan menggunakan model pembelajaran untuk meningkatkan pemahaman konsep peserta didik, salah satunya dengan model pembelajaran Learning Cycle 5E menggunakan real laboratory dan virtual laboratory. Tujuan penelitian ini adalah untuk mengetahui pengaruh penggunaan model pembelajaran Learning Cycle 5E dengan real laboratory dan virtual laboratory terhadap kualitas proses pembelajaran pada materi kesetimbangan kimia. Rancangan penelitian ini menggunakan rancangan eksperimen semu dengan analisis data deskriptif. Populasi penelitian ini adalah siswa kelas XI MIA SMA Negeri 2 Malang, menggunakan convenience sampling dan diperoleh sampel penelitian siswa kelas XI MIA 4 (LC 5E dengan real laboratory) dan siswa kelas XI MIA 5 (LC 5E dengan virtual laboratory). Instrumen yang digunakan berupa instrumen perlakuan yang terdiri dari RPP dan bahan ajar, serta instrumen pengukuran yang terdiri dari lembar RTOP, lembar observasi keterlaksanaan pembelajaran, serta lembar penilaian afektif dan psikomotorik. Hasil penelitian menunjukkan bahwa kualitas proses dengan model pembelajaran LC 5E menggunakan real laboratory dan virtual laboratory terlaksana dengan baik, serta penilaian afektif dan psikomotorik peserta didik mencapai ketuntasan sebesar 100%.
Kata kunci: kualitas proses, real laboratory, virtual laboratory.
Peer-to-Peer Lending in Surabaya: How It Drives Regional Economy?
Authors: Mahardhika Galih Satria 
Published: July 2019

Financial technology, or so called as “Fintech”, has been remarked as a disruptive idea that changed our current financial system. In Indonesia, one of the emerging financial practices related to Fintech is the online-based peer-to-peer lending (P2PL). This research has two objectives: to explore current scheme of P2PL in Surabaya and to learn how P2PL drives the economy of Surabaya. To meet the objectives, numbers of existing papers are being reviewed related to the matter of P2PL and Micro, Small and Medium Enterprises (MSMEs). Primary data is also gathered through in-depth interview from two basic stakeholders of P2PL in Surabaya: the provider of fintech apps and the owner of MSMEs who is benefiting from the fintech apps. The fintech provider is interviewed regarding to the channeling scheme of funds from the lenders to the MSMEs, while the MSME is interviewed related to the escalation of their business after receiving funds from the P2PL provider. By exploring this topic, the scheme of P2PL and the importance of P2PL to drive regional economy are being clearly described. The results are: the funding from P2PL providers help the MSMEs to boost their business performance, and the boosted MSMEs are affecting the regional economy. Keywords: Fintech, Peer-to-peer lending, MSMEs, lending scheme
NON-TARIFF MEASURES IMPACT ON INDONESIAN FISHERY EXPORT
Authors: Handoyo Rossanto Dwi 
Published: July 2019

This study aims to analyze the impact of Non tariff measures using sanitary and phytosanitary policy (SPS) and technical trade barriers (TBTs) on fishery exports of Indonesia and its trading partner countries such as China, South Korea, Vietnam, Canada, Russia and the European Union in period of 2007 to 2016. SPS and TBT are measured using inventory approach in the form of coverage ratio. In addition, this study uses a gravity model and panel data regression method. The results of this study indicate that the variables GDP of exporting country and GDP of importing country have a positive and significant effect on Indonesian fishery exports. Distance and SPS have a negative and significant effect on Indonesian fishery exports, while TBT has no effect on Indonesian fishery exports. Keywords: Export, SPS and TBT, Fishery Export, coverage ratio
PARIWISATA PENGARUHNYA TERHADAP EKONOMI : ANALISIS KAJIAN ASAL KUNJUNGAN WISATAWAN MANCANEGARA
Authors: Ksamawan Kdwi wahyu , Maskie Ghozali , Kaluge David 
Published: July 2019

The influence of foreign tourist arrivals based on the region of origin on economic growth was analyzed in this study, using GDP data as a proxy for economic growth, the number of tourist visits, the Consumer Price Index, and the monthly period of exchange for 2007-2016. This study uses secondary data with the Error Correction Model (ECM) regression method with short and long-term calculations. The results showed that the variable number of tourist visits had an effect on GDP in the continents of Asia, Europe, Middle-East, and Oceania while in the long run in all continents except America. The exchange rate variable in the short term has a negative effect on GDP in the American Continent and the Middle East, while in the long run, the exchange rate variable has a positive effect on GDP in the Asean continent and Europe. The CPI variable only has a positive effect on GDP in the long run for all continents except America. So that it can be concluded that not all continents have a positive impact on GDP, one of which is the American continent, so in order to optimize and increase economic growth, it should be stressed that the cost of developing the tourism sector in America should be allocated more proportionally or diverted to continents of Asia, ASEAN, Oceania, Europe and the Middle East.of developing the tourism sector in America should be allocated more proportionally or diverted to continents of Asia, ASEAN, Oceania, Europe and the Middle East. Keywords: Error Correction Model,GDP, Tourism
MENINGKATKAN HASIL BELAJAR MATEMATIKA MELALUI MODEL PEMBELAJARAN KOOPERATIF TIPE MAKE A MATCH PADA MATERI ARITMETIKA SOSIAL
Authors: Sukaisih Elya 
Published: July 2019

Abstrak: Penelitian ini bertujuan untuk meningkatkan hasil belajar siswa kelas VII B MTsN 1 Hulu Sungai Utara melalui model pembelajaran kooperatif tipe make a match pada materi aritmetika sosial. Pembelajaran kooperatif tipe make a match adalah model pembelajaran di mana siswa bekerja sama mencari pasangan masing-masing sambil belajar mengenal suatu konsep atau topik dalam suasana yang menyenangkan. Penelitian ini merupakan penelitian tindakan kelas yang dilaksanakan dalam dua siklus. Terdapat dua kali pertemuan dalam setiap siklus. Instrumen yang digunakan pada penelitian ini adalah lembar observasi kegiatan siswa, lembar observasi kegiatan guru serta tes tertulis. Tes hasil belajar dan teknik observasi digunakan untuk mengumpulkan data, sedangkan teknik persentase digunakan untuk menganalisis data. Hasil penelitian menunjukkan kegiatan belajar guru lebih aktif dan kreatif, serta keaktifan belajar siswa meningkat. Selain itu terjadi peningkatan ketuntasan belajar siswa dari 57,14% pada siklus I menjadi 78.57% pada siklus II. Kata kunci: Model pembelajaran kooperatif, Make a Match, hasil belajar Abstract: The research aimed to improve the learning outcomes of VII B grade of MTsN 1 Hulu Sungai Utara through cooperative learning model type make a match in social arithmetic material. Cooperative learning type make a match is a learning model where students work together to find their partner while learning to recognize a concept or topic in a pleasant atmosphere. This research is a classroom action research conducted in two cycles. There are two meetings in each cycle. The instru­ments used in this study were observation sheets of student activities, observation sheets of teacher activities and written tests. Tests of learning outcomes and observation techniques are used to collect data, while percentage techniques are used to analyze data. The results of the study show that teacher learning activities are more active and creative, and student learning activeness is increasing. In addition, there was an increase in student learning outcomes from 57.14% in the first cycle to 78.57% in the second cycle. Keywords: Cooperative Learning Model, Make a Match, learning outcomes.
MENINGKATKAN HASIL BELAJAR MATEMATIKA SISWA KELAS VIII A MTS RAHMANIYAH DENGAN PENERAPAN MODEL PEMBELAJARAN NUMBER HEADS TOGETHER (NHT) PADA MATERI LINGKARAN
Authors: Sudarmawan Heppi 
Published: July 2019

Abstrak: Tujuan dari penelitian ini adalah mendeskripsikan pembelajaran dengan penerapan model pembelajaran Number Heads Together (NHT) di kelas VIII A MTs Rahmaniyah pada materi lingkaran dan untuk mengetahui peningkatan hasil belajar siswa. Penelitian yang dilakukan adalah penelitian tindakan kelas dengan meng­gunakan model spiral Kemmis dan McTaggart. Subjek dari penelitian ini sebanyak 20 orang siswa. Soal tes dan lembar observasi adalah instrumen yang digunakan untuk mengambil data penelitian. Hasil penelitian menunjukkan bahwa persentase ketuntasan siswa mencapai 65,00 % pada siklus I. Ketuntasan meningkat menjadi 80,00 % pada siklus II. Hasil ini menunjukkan bahwa penggunaan model pem­belajaran NHT dapat meningkatkan hasil belajar siswa kelas VIII A MTs Rahmaniyah pada materi lingkaran. Kata Kunci: Number Heads Together, Hasil Belajar, Lingkaran Abstract: The purpose of this study was to describe learning by applying the Number Heads Together (NHT) learning model in VIII A grade of MTs Rahmaniyah on circle material and to determine the improvement of student learning outcomes. The research conducted was classroom action research using the spiral model Kemmis and McTaggart. The subjects of this study were 20 students. Test questions and observation sheets are instruments used to retrieve research data. The results showed that the percentage of student completeness for circle material reached 65.00% in cycle I. The completeness increased to 80.00% in cycle II. These results indicate that the use of the NHT learning model can improve the learning outcomes of class VIII A MTs Rahmaniyah in circle material. Keywords: Number Heads Together, Learning outcomes, Circle.
PERAN PETANI KUNCI (COCOA DOCTOR) DALAM ADOPSI PAKET PENINGKATAN PRODUKSI PETANI KAKAO SERTIFIKASI
Authors: Sumiati Sumiati , Arsyad Muhammad , Diansari Pipi 
Published: July 2019

AbstractThis study aims to determine: 1) the role of cocoa doctor in adoption production package; 2) cocoa farmer's response to the presence of cocoa doctor; 3) the level of adoption of production increasing package (called 3PP) of cocoa farmers. This research was conducted in Maliwowo Village, Eastern Luwu, South Sulawesi. Samples were 36 people, by simple random sampling method. The analysis employed scoring analysis. The results shows that: 1) the role of cocoa doctor in adoption 3PP in terms of information delivery, absorption ability of information, group planning, cooperation and group institutionalized is the middle category of 53.78%; 2) farmers have agreed response to the presence of cocoa doctor; and 3) farmers adoption levels to 3PP are in the medium category (75%). This implies that the role of cocoa doctor could be expected to improve adoption of 3PP. Keywords: cocoa doctor; cocoa farmers; adoption.
STRATEGI PENGEMBANGAN USAHA KULINER
Authors: Safitri Irvina , Salman Darmawan , Rahmadani Rahmadani 
Published: July 2019

Lemang is one of traditional food made from raw material of sticky rice (black and white) wrapped with banana leaf and put into bamboo container from Bangkala Subdistrict, Jeneponto Regency. This study aims to: (1) Describe the strategy in maintaining relationships with providers Lemang Dg Awing in District Bangkala (2) Describe the strategy in maintaining the relationship with the business of Lemang Dg Awing. (3) Describe the strategy in maintaining the quality of lemang in the business of Lemang Dg Awing. (4) Analyzing the business continuity hole in the case of Lemang Dg Awing business. This study used qualitative descriptive, participatory analysis tools and in-depth interviews, with research locations in Bangkala District, Jeneponto Regency, South Sulawesi. The results concluded that: 1. Strategy built by Dg. Awing with suppliers With suppliers for suppliers Invites suppliers to make events, Presents lemang to suppliers. Provide additional bonus through channeling for purchases of lemang 2. Dg Awing always maintains relationships with its employees such as: Always work in the morning, Invites employees at the time of the event, Provides support during times of big days, Provides money support, Prepares cold food and drinks on the part burning, especially during the day, Inviting vacation together. 3. Dg Awing Always pay attention to 6 basic components to maintain the quality of lemang remain stored, such as aroma, shape, size, taste, texture and color lemang 4. Dg. Awing continues to control 3 aspects for business continuity related to raw material suppliers, Maintain and maintain good relationships to its workers. Keep maintaining the quality of the lemang itself to continue to increase sales volume and increase consumer loyality in buying lemang.Keywords: lemang; traditional food; development strategy.