bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Efficient Strategy for Boosting Photogenerated Charge Separation by Using Porphyrins as Interfacial Charge Mediators
Authors: Ning Xingming , Lu Bingzhang , Zhang Zhen , Du Peiyao , Ren Hongxia , Shan Duoliang , Chen Jing , Gao Yunjing , Lu Xiaoquan 
Published: September 2019

AbstractSurface recombination at the photoanode/electrolyte junction seriously impedes photoelectrochemical (PEC) performance. Through coating of photoanodes with oxygen evolution catalysts, the photocurrent can be enhanced; however, current systems for water splitting still suffer from high recombination. We describe herein a novel charge transfer system designed with BiVO4 as a prototype. In this system, porphyrins act as an interfacial‐charge‐transfer mediator, like a volleyball setter, to efficiently suppress surface recombination through higher hole‐transfer kinetics rather than as a traditional photosensitizer. Furthermore, we found that the introduction of a “setter” can ensure a long lifetime of charge carriers at the photoanode/electrolyte interface. This simple interface charge‐modulation system exhibits increased photocurrent density from 0.68 to 4.75 mA cm−2 and provides a promising design strategy for efficient photogenerated charge separation to improve PEC performance.
CuII‐Containing 1‐Aminocyclopropane Carboxylic Acid Oxidase Is an Efficient Stereospecific Diels–Alderase
Authors: Ghattas Wadih , Dubosclard Virginie , Tachon Sybille , Beaumet Morane , Guillot Régis , Réglier Marius , Simaan A. Jalila , Mahy Jean‐Pierre 
Published: September 2019

AbstractIn the context of developing ecofriendly chemistry, artificial enzymes are now considered as promising tools for synthesis. They are prepared in particular with the aim to catalyze reactions that are rarely, if ever, catalyzed by natural enzymes. We discovered that 1‐aminocyclopropane carboxylic acid oxidase reconstituted with CuII served as an efficient artificial Diels–Alderase. The kinetic parameters of the catalysis of the cycloaddition of cyclopentadiene and 2‐azachalcone were determined (KM=230 μm, kapp=3 h−1), which gave access to reaction conditions that provided quantitative yield and >99 % ee of the (1S,2R,3R,4R) product isomer. This unprecedented performance was rationalized by molecular modeling as only one docking pose of 2‐azachalcone was possible in the active site of the enzyme and this was the one that leads to the (1S,2R,3R,4R) product isomer.
An Illumination‐Assisted Flexible Self‐Powered Energy System Based on a Li–O2 Battery
Authors: Yang Xiao‐yang , Feng Xi‐lan , Jin Xin , Shao Ming‐zhe , Yan Bao‐lin , Yan Jun‐min , Zhang Yu , Zhang Xin‐bo 
Published: September 2019

AbstractThe flexible Li‐O2 battery is suitable to satisfy the requirements of a self‐powered energy system, thanks to environmental friendliness, low cost, and high theoretical energy density. Herein, a flexible porous bifunctional electrode with both electrocatalytic and photocatalytic activity was synthesized and introduced as a cathode to assemble a high‐performance Li‐O2 battery that achieved an overpotential of 0.19 V by charging with the aid of solar energy. As a proof‐of‐concept application, a flexible Li‐O2 battery was constructed and integrated with a solar cell via a scalable encapsulate method to fabricate a flexible self‐powered energy system with excellent flexibility and mechanical stability. Moreover, by exploring the evolution of the electrode morphology and discharge products (Li2O2), the charging process of the Li‐O2 battery powered by solar energy and solar cell was demonstrated.
Inhibiting VOPO4⋅x H2O Decomposition and Dissolution in Rechargeable Aqueous Zinc Batteries to Promote Voltage and Capacity Stabilities
Authors: Shi Hua‐Yu , Song Yu , Qin Zengming , Li Cuicui , Guo Di , Liu Xiao‐Xia , Sun Xiaoqi 
Published: September 2019

AbstractVOPO4⋅x H2O has been proposed as a cathode for rechargeable aqueous zinc batteries. However, it undergoes significant voltage decay in conventional Zn(OTf)2 electrolyte. Investigations show the decomposition of VOPO4⋅x H2O into VOx in the electrolyte and voltage drops after losing the inductive effect from polyanions.PO43− was thus added to shift the decomposition equilibrium. A high concentration of cheap, highly soluble ZnCl2 salt in the electrolyte further prevents VOPO4⋅x H2O dissolution. The cathode shows stable capacity and voltage retentions in 13 m ZnCl2/0.8 m H3PO4 aqueous electrolyte, in direct contrast to that in Zn(OTf)2 where the decomposition product VOx provides most electrochemical activity over cycling. Sequential H+ and Zn2+ intercalations into the structure are revealed, delivering a high capacity (170 mAh g−1). This work shows the potential issue with polyanion cathodes in zinc batteries and proposes an effective solution using fundamental chemical principles.
Synergistic Doping and Intercalation: Realizing Deep Phase Modulation on MoS2 Arrays for High‐Efficiency Hydrogen Evolution Reaction
Authors: Deng Shengjue , Luo Mi , Ai Changzhi , Zhang Yan , Liu Bo , Huang Lei , Jiang Zheng , Zhang Qinghua , Gu Lin , Lin Shiwei , Wang Xiuli , Yu Lei , Wen Jianguo , Wang Jiaao , Pan Guoxiang , Xia Xinhui , Tu Jiangping 
Published: September 2019

AbstractA synergistic N doping plus PO43− intercalation strategy is used to induce high conversion (ca. 41 %) of 2H‐MoS2 into 1T‐MoS2, which is much higher than single N doping (ca. 28 %) or single PO43− intercalation (ca. 10 %). A scattering mechanism is proposed to illustrate the synergistic phase transformation from the 2H to the 1T phase, which was confirmed by synchrotron radiation and spherical aberration TEM. To further enhance reaction kinetics, the designed (N,PO43−)‐MoS2 nanosheets are combined with conductive vertical graphene (VG) skeleton forming binder‐free arrays for high‐efficiency hydrogen evolution reaction (HER). Owing to the decreased band gap, lower d‐band center, and smaller hydrogen adsorption/desorption energy, the designed (N,PO43−)‐MoS2/VG electrode shows excellent HER performance with a lower Tafel slope and overpotential than N‐MoS2/VG, PO43−‐MoS2/VG counterparts, and other Mo‐base catalysts in the literature.
Relationship between Pt particle size and catalyst activity for catalytic oxidation of ultrahigh‐concentration formaldehyde
Authors: Ma Luyao , Liu Chenxin , Guan Qingxin , Li Wei 
Published: September 2019

The effects of particle size and kinetics of Pt/activated carbon (AC) catalysts on catalytic oxidation of formaldehyde (HCHO) were investigated. AC, f‐SiO2 and MCM‐41 were used as supports to prepare low‐Pt‐content catalysts using H2 reduction. Pt/AC catalyst shows the highest activity with the largest Pt particle size. By contrast, 0.1 wt% Pt/AC reduced using KBH4 has much higher activity than that reduced using H2, which can oxidize HCHO completely over 6000 ppm at 60°C in a fixed bed reactor. Transmission electron microscopy and X‐ray photoelectron spectroscopy results indicate that Pt/AC‐KBH4 has larger Pt particles and lower valence state than Pt/AC‐H2, which may be attributed to the ligand effect between Pt4+ and the AC support. The result of O2 temperature‐programmed oxidation suggests that highly dispersed Pt4+ ions have stronger interaction with AC support and thus are harder to be reduced by H2. Furthermore, Pt/AC is structure‐sensitive and larger‐sized Pt particles result in a high conversion of HCHO. Investigation of kinetics indicated that it is a zero‐order reaction for such a high HCHO concentration condition for Pt/AC‐KBH4.
Stochastic modeling of quality of systems operating in a heterogeneous environment
Authors: Cha Ji Hwan , Finkelstein Maxim 
Published: September 2019

AbstractWe consider systems that are subject to an external mixed Poisson shock process. Each shock can result in a failure of a system with a given probability and is survived with the complementary probability. Each shock additionally decreases the quality function that describes the performance of a system, thus forming the corresponding stochastic process. Expectations (unconditional and conditional on survival) and relevant variability characteristics for the stochastic quality function are derived. Some monotonicity properties of the conditional quality function are investigated and the future values of this function are derived.
“Hungry for Knowledge”: Towards a Meso‐History of the Environmental Sciences
Authors: Güttler Nils 
Published: September 2019

AbstractIn recent years, cultural studies and cultural theory have experienced a new wave of ecological thought. Despite the engagement with the Anthropocene the history of ecology and the environmental sciences has remained somewhat of a puzzle. This goes especially for the 20th century, a period when the sciences of the environment came to matter on a broader scale. Why do we actually know so little about the environmental sciences in the 20th century? And what could a history of the environmental sciences in that period look like? This article answers these questions with two interrelated arguments. First, by reflecting on different approaches to write the history of ecology since the 1970s, it uncovers crucial entanglements between the history of science and ecological thought that created blind spots regarding the environmental sciences in the 20th century. Second, it argues for a shift in scales of analysis—towards meso‐scales. With a more regional approach historians can engage with the often‐neglected aspects of the political and economic history of the environmental sciences in the 20th century and thereby also reveal their fundamental infrastructural dimension. Because at its core, the article claims, the environmental sciences were and are essentially infrastructural sciences.
A microtitre chemiluminescence sensor for detection of pyrethroids based on dual‐dummy‐template molecularly imprinted polymer and computational simulation
Authors: Huang Jing Jie , Liu Jing , Liu Ju Xiang , Wang Jian Ping 
Published: September 2019

AbstractThe residues of pyrethroids in foods of animal origin are dangerous to the consumers, so this study presented a chemiluminescence sensor for determination of pyrethroids in chicken samples. A dual‐dummy‐template molecularly imprinted polymer capable of recognizing 10 pyrethroids was synthesized. The results of computation simulation showed that the specific 3D conformations of the templates had important influences on the polymer' recognition ability. The polymer was used to prepare a sensor on conventional 96‐well microplates, and the sample solution was added into the wells for direct absorption. The absorbed analytes were initiated with the bis(2,4,6‐trichlorophenyl)oxalate–H2O2–imidazole system, and the chemiluminescence intensity was used for analyte quantification. Results showed that one assay was finished within 12 min, and this sensor could be reused four times. The limits of detection for the 10 analytes were in the range o0.3–6.0 pg/ml, and the recoveries from the standards of fortified blank chicken samples were in the range 70.5–99.7%.
Bioprocessing in the Digital Age: The Role of Process Models
Authors: Narayanan Harini , Luna Martin F. , von Stosch Moritz , Cruz Bournazou Mariano Nicolas , Polotti Gianmarco , Morbidelli Massimo , Butté Alessandro , Sokolov Michael 
Published: September 2019

AbstractIn this age of technology, the vision of manufacturing industries built of smart factories is not a farfetched future. As a prerequisite for Industry 4.0, industrial sectors are moving towards digitalization and automation. Despite its tremendous growth reaching a sales value of worth $188 billion in 2017, the biopharmaceutical sector distinctly lags in this transition. Currently, the challenges are innovative market disruptions such as personalized medicine as well as increasing commercial pressure for faster and cheaper product manufacturing. Improvements in digitalization and data analytics have been identified as key strategic activities for the next years to face these challenges. Alongside, there is an emphasis by the regulatory authorities on the use of advanced technologies, proclaimed through initiatives such as Quality by Design (QbD) and Process Analytical Technology (PAT). In the manufacturing sector, the biopharmaceutical domain features some of the most complex and least understood processes. Thereby, process models that can transform process data into more valuable information, guide decision‐making, and support the creation of digital and automated technologies are key enablers. This review summarizes the current state of model‐based methods in different bioprocess related applications and presents the corresponding future vision for the biopharmaceutical industry to achieve the goals of Industry 4.0 while meeting the regulatory requirements.
Permeabilized Escherichia coli Whole Cells Containing Co‐Expressed Two Thermophilic Enzymes Facilitate the Synthesis of scyllo‐Inositol from myo‐Inositol
Authors: Li Yuan , Liu Shan , You Chun 
Published: September 2019

AbstractScyllo‐inositol (SI), a stereoisomer of inositol, is regarded as a promising therapeutic agent for Alzheimer's disease. Here, an in vitro cofactor‐balance biotransformation for the production of SI from myo‐inositol (MI) by thermophilic myo‐inositol 2‐dehydrogenase (IDH) and scyllo‐inositol 2‐dehydrogenase (SIDH) is presented. These two enzymes (i.e., IDH and SIDH from Geobacillus kaustophilus) are co‐expressed in Escherichia coli BL21(DE3), and E. coli cells containing the two enzymes are permeabilized by heat treatment as whole‐cell catalysts to convert MI to SI. After condition optimizations about permeabilized temperature, reaction temperature, and initial MI concentration, about 82 g L−1 of SI is produced from 250 g L−1 of MI within 24 h without any cofactor supplementation. This final titer of SI produced is the highest to the authors’ limited knowledge. This study provides a promising method for the large‐scale industrial production of SI.
Taking a holistic view of PEST‐containing nuclear protein (PCNP) in cancer biology
Authors: Afzal Attia , Sarfraz Muhammad , Li Guang‐Lei , Ji Shao‐Ping , Duan Shao‐Feng , Khan Nazeer Hussain , Wu Dong‐Dong , Ji Xin‐Ying 
Published: September 2019

AbstractPolypeptide sequences enriched with proline (P), glutamic acid (E), aspartic acid (D) and serine (S)/ threonine (T) (PEST) have been reported to be the most abundant and frequently distributed at the cellular level. There is growing evidence that PEST sequences act as proteolytic recognition signals for degradation of residual proteins which is critical for activation or deactivation of regulatory proteins involved in cellular signaling pathways of cell growth, differentiation, stress responses and physiological death. A PEST containing nuclear protein (PCNP) was demonstrated as a tumor suppressor in a neuroblastoma cancer model and tumor promoter in lung adenocarcinoma cancer model. Its unique properties like ubiquitination by NIRF, co‐localization with NIRF in nucleus and tumor progression attract the attention of researchers. PCNP was reported to be ubiquitinated by ring finger protein NIRF in E3 ligase manner and as modulator of MAPK and PI3K/AKT/mTOR signaling pathways. In this review, we summarize PCNP linked DNA damage response, Post translational modifications, and transportation to address initiation, prognosis, and resistance of tumor cells in terms of cell cycle regulation, transcription and apoptosis. Hence, we demonstrate PCNP as a novel target in cancer diagnosis and treatment.
Outcomes of extracorporeal membrane oxygenation support in the cardiac catheterization laboratory
Authors: Parr Christopher J. , Sharma Rajat , Arora Rakesh C. , Singal Rohit , Hiebert Brett , Minhas Kunal 
Published: September 2019

AbstractObjectivesThe aims of this single‐center retrospective study were to characterize and determine predictors of 30‐day survival in a cohort of patients requiring venoarterial extracorporeal membrane oxygenation (VA‐ECMO) supported cardiopulmonary resuscitation (E‐CPR) in the cardiac catheterization laboratory (CCL) for cardiac arrest (CA) or refractory cardiogenic shock (CS).BackgroundWhile safety in the CCL has improved, periprocedural mortality from CA remains high. The application of VA‐ECMO is an emerging form of resuscitation with a paucity of data evaluating its use in the CCL for CA or CS.MethodsAll consecutive patients aged 18 years or older presenting to a single CCL from October 2010 to May 2018 who required E‐CPR for CA or refractory CS were included. The primary outcome of our study was overall survival 30 days from VA‐ECMO initiation. Secondary outcomes included 1‐year survival, hospital length of stay, and ECMO related complications.ResultsSixty‐two patients with a mean age of 60 ± 9 years, 63% male, were included. VA‐ECMO was initiated for CA in 39 patients (63%) and for CS in 23 patients (37%). The median ECMO duration was 48 hr. Overall 30‐day survival was 47% (CA group 44% vs. CS group 52%; p = .414). One‐year survival was 44%. Initial serum creatinine (OR 1.18 per 10 μmol/L increase; p = .016; AUC = 0.65) was the only multivariate predictor of 30‐day mortality.ConclusionsThe use of VA‐ECMO in the CCL is feasible, demonstrating 47% 30‐day survival, largely persistent to 1 year, in a cohort that otherwise has extremely high mortality.
Effect of saline organic acid solutions applied during soft wheat tempering on microbial load and flour functionality
Authors: Sabillón Luis , Stratton Jayne , Rose Devin , Bianchini Andréia 
Published: September 2019

AbstractBackground and objectivesIn recent years, special concern has been raised about the safety of wheat‐based products. In light of several incidents of foodborne illness associated with flour, the objectives of this study were designed to (a) evaluate the efficacy of saline organic acids solutions to reduce the natural microbiota of soft wheat grain and flour, and (b) to assess the impact of these tempering solutions on the functional properties of soft wheat flour.FindingsThe microbial load of the tempered wheat was significantly reduced by all saline organic acid treatments. The combination of 5.0% lactic acid–NaCl was the most effective against aerobic mesophilic bacteria and Enterobacteriaceae, with average reductions of 3.1 ± 0.1 and 4.5 ± 0.0 log CFU/g, respectively. In addition, this tempering solution yielded flour with a significantly lower microbial load compared with the control. Tempering with saline organic acid solutions did result in minor, but significant, variations in the solvent retention capacity profile of some flours. However, the treatments did not cause significant changes in the pasting profile of flours or in the physical characteristics and texture profile of baked cookies.ConclusionsThe addition of organic acids and NaCl to the tempering water improved the microbiological quality of the wheat grain and the resulting flour without compromising its functionality.Significance and noveltyThis study evaluates the inclusion of antimicrobial agents in the water used to temper wheat grain prior to milling as a practical method to reduce the number of microbial contaminants in flour and flour‐based foods that are at risk for consumption without cooking or any killing step.
Starch digestibility properties of bread from hard red spring wheat cultivars released in the last 100 years
Authors: Simsek Senay , Budak Bilge , Schwebach Catherine Suzanne , Ovando‐Martínez Maribel 
Published: September 2019

AbstractBackground and objectivesThere have been concerns that there is a link between the carbohydrate properties of modern wheat cultivars and increasing levels of obesity and diabetes worldwide. This research was conducted to determine starch composition and digestibility of thirty historic and modern hard red spring wheat cultivars and to evaluate whether there were statistical differences between the genotypes in relationship to the release year.FindingsThere were no significant differences (p < .05) between historic and modern wheat cultivars for amylose content in flour or for amylose and amylopectin molecular weight in flour and bread samples. Starch digestibility in bread did not show significant differences (p < .05) among cultivars, and there was no significant correlation (p < .05) with the release year and the SDS, HI, and eGI.ConclusionsStarch digestibility of bread prepared from historic and modern wheat cultivars is not related to release year. It is unlikely that wheat breeding practices have caused wheat to be more rapidly digestible and the digestibility could be more related with the bread‐making process or formula than the release year.Significance and noveltyKnowledge about the effect of the release year on starch in historical and modern wheat cultivars helps us to support that wheat breeding is not related to increased incidence of chronic disease.
Chronic hepatitis associated with antiribosomal‐P autoantibodies in a 14‐year‐old girl
Authors: Mejean Coline , Bertin Daniel , Guetta Kim , Desaldeleer Cécile , Butori Mathilde , Roquelaure Bertrand , Fabre Alexandre 
Published: September 2019

AbstractWe reported the first pediatric case of auto‐immune hepatitis with positive anti‐P antibodies. On the basis of our findings, adding auto anti‐P screening in pediatric seronegative HAI may be recommended.
Small and Narrowly Distributed Copper Nanoparticles Supported on Carbon Prepared by Surface Organometallic Chemistry for Selective Hydrogenation and CO2 Electroconversion Processes
Authors: Mavrokefalos Christos K. , Kaeffer Nicolas , Liu Hsueh‐Ju , Krumeich Frank , Copéret Christophe 
Published: September 2019

AbstractCopper nanoparticles (Cu NPs) are intensively investigated in recent years due to their promising catalytic properties, e. g. selective alkyne hydrogenation and CO2 electrocatalytic reduction. While dispersing small supported Cu nanoparticles is relatively straightforward on most oxides, obtaining the corresponding small and well dispersed nanoparticles on carbon supports is more challenging because of weaker metal‐support interactions resulting typically in larger particles and broader distribution. Here, we show that Surface Organometallic Chemistry can be applied on carbon support and allows the generation of small and narrowly dispersed Cu NPs (4.0+/−1.4 nm) supported on carbon. The thus‐obtained Cu nanoparticles are catalytically active in the selective semihydrogenation of an alkyne and the hydrogenation of ethyl cinnamate into the corresponding saturated ester. Moreover, these Cu NPs dispersed on a conductive support catalyze the electroconversion of CO2 towards C1 (CO, HCOO−, CH4) and C2 (C2H4) reduction products, with high Cu‐specific activity towards methane.
An All‐Prussian‐Blue‐Based Aqueous Sodium‐Ion Battery
Authors: Wang Baoqi , Wang Xiao , Liang Chu , Yan Mi , Jiang Yinzhu 
Published: September 2019

AbstractAqueous rechargeable sodium‐ion batteries have received great attention as an alternative to meet the growing demand of large‐scale electrochemical energy storage systems due to the earth‐abundant and low‐cost sodium resources. In this study, an all Prussian‐blue‐based aqueous sodium‐ion battery is constructed using copper and iron‐based Prussian blue analogues as cathode and anode, respectively, and neutral NaNO3solution as electrolyte. The battery delivers an average output voltage of 0.70 V, a specific capacity of 50 mAh g−1, and good rate capability with ∼86 % capacity retention over 250 cycles at 5 C. Moreover, the cathode, anode, and electrolyte materials are inexpensive, environmentally friendly, and inherently safe, which is particularly attractive for large‐scale energy storage applications.