bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the Impact of E-Learning on Employees' Performance and Work Commitment: A Case Study of Private Sector School and College Employees in SWAT
Authors: Akhter Hussain  , Prof. Dr. Hazrat Bilal  , Dr. Nasir Shaheen  , Rezwan Ullah  , Asif Saud Jan  , Abdul Mateen  
Published: December 2024

This study investigates the impact of e-learning on employees' performance and work commitment; private sector schools and colleges in SWAT. The research aim is to find and provide insights into the effectiveness of e-learning initiatives taken in improving educational institutions and employee performance. A qualitative case study approach; semi-structured interviews and formal document analysis to conduct the study. An online survey was conducted where 200 employees participated. This included both closed-ended and open-ended questions. Descriptive statistics shows 45% of respondents were aged 25-34, with a gender distribution of 60% male and 40% female. Mostly participants (50%) had a Bachelor’s degree, and 30% had a Master’s degree. This method showed that E-learning practices adopted by employees at 30% participated daily, 40% weekly, and 20% monthly. The satisfaction with e-learning was found as 25% very satisfied and 40% satisfied in the educational setting. The study results finds that e-learning has significantly improved employee performance by enabling e-skill acquisition and knowledge transfer that leadins to improvements in teaching effectiveness and student outcomes. It also helps in improved employee work commitment by providing, continuous professional development opportunities. The finding reveals a positive correlations, found between e-learning participation and job performance (r = 0.65, p < 0.01) and, also between e-learning satisfaction and work commitment (r = 0.62, p < 0.01). This study is limited to private sector educational institutions in SWAT that may affect the generalizability of the findings towards public sector or other large organizations in educational sector. This research confirms the e-learning impact on employee performance and work commitment in private sector educational institutions. Therefore, future research could be expanded to the scope where other regions and sectors; public sector and non-profit institutions can be included, to provide a more valuable understanding of e-learning’s impact in such setting. The research findings and observations contributes to the existing body of knowledge by providing empirical evidence-the impact of e-learning on employee performance and work commitment in SWAT’s private sector schools and colleges. It mainly highlights the importance of adopting and practicing effective e-learning strategies to improve educational outcomes and to support professional growth.
“Vístete como quieras, actúa como quieras”. Trayectorias, experiencias y redes de apoyo entre una muestra de personas trans
Authors: Álvarez Bernardo Gloria , Vicente Martínez Francisco Javier , Piedra Cristóbal Julio 
Published: December 2024

The purpose of this research was to explore the situation of transgender people in Spain, focusing on the analysis of their trajectories and identity experiences, as well as the role played by family, friends and associations throughout this process. To this end, qualitative research was carried out with 13 transgender people. Semi-structured interviews were used and a content analysis was carried out using the phenomenological approach. Among the main results found, it is worth highlighting that the family and peer group are essential references for trans people. In particular, having their support and recognition can be fundamental during the process of identity construction. Within friendships, it is important to point out that many of the people interviewed value their LGTB friends positively. We conclude the importance that professionals, such as social workers, can have in direct and indirect intervention with transgender people to improve their emotional well-being, as well as an advance towards social justice.
Las personas trans se enfrentan a un contexto socio-político marcado por la cisheteronormatividad y en el que su identidad de género puede ser causa de rechazo y discriminación en distintos ámbitos (Gallardo y Espinosa, 2019). El propósito de esta investigación ha sido explorar la situación de un grupo de personas trans en España, centrándose en el análisis de sus experiencias identitarias, así como el papel que han desempeñado la familia, las amistades y las asociaciones en sus trayectorias vitales. Para ello, se realizó una investigación cualitativa con 13 personas trans. Se utilizaron entrevistas semiestructuradas y se procedió con un análisis de contenido partiendo del enfoque fenomenológico. Entre los principales resultados hallados, destacar que la familia y el grupo de pares son referentes esenciales para las personas trans. En particular, tener su apoyo y reconocimiento puede ser fundamental durante el proceso de construcción de la identidad. Dentro de las amistades, es importante señalar que muchas de las personas entrevistadas valoran positivamente a sus amistades LGTB. Se concluye la importancia que profesionales, como trabajadores/as sociales, pueden tener desde una práctica afirmativa en la intervención directa e indirecta con las personas trans para mejorar su bienestar emocional, así como un avance hacia la justicia social.
Agrupaciones Juveniles de Calle: apuntes para políticas públicas responsables
Authors: Prades-Caballero Virginia , Navarro-Pérez Jose-Javier , Carbonell Ángela , Feixa-Pàmpols Carles 
Published: December 2024

Street Youth Groups in Spain are complex organisations that are structured around a shared ideology and values, fostering internal cohesion, group identification and a strong sense of belonging among their members. This article offers an exhaustive analysis of the definitions, origin, composition and characteristics of these groups in the Spanish context, as well as the profile of their members. The aim is to understand both their origin, permanence over time and current challenges in order to propose mechanisms that promote pacification and the resolution of conflicts associated with their presence in society.
Las Agrupaciones Juveniles de Calle en España son organizaciones complejas que se estructuran en torno a una ideología y valores compartidos, fomentando la cohesión interna, la identificación grupal y un fuerte sentido de pertenencia entre sus miembros. Este artículo ofrece un análisis exhaustivo de las definiciones, origen, composición y características de estos grupos en el contexto español, así como del perfil de sus integrantes. El objetivo es comprender tanto su origen, permanencia en el tiempo y desafíos actuales a fin de proponer mecanismos que promuevan la pacificación y la resolución de conflictos asociados a su presencia en la sociedad.
Differential Gene Expression
Authors: Hoffman Megan 
Published: December 2024

The trillions of cells in the human body can be categorized into hundreds of specialized cell types. All of these cells arise from the original fertilized egg and contain the same DNA. Differences among the cell types arise because cells selectively express some genes but not others. In this activity, students will explore how cells utilize transcription factors and enhancer regions to express different genes. Students who complete the activity will be able to: (1) explain and illustrate how cells that contain the same DNA can produce different proteins; (2) predict the activity of genes based on the presence of relevant transcription factors and enhancer regions; (3) Form an argument and reach a conclusion supported with evidence from the Models and from knowledge of molecular biology. [Process goal: critical thinking].

Level: Undergraduate

Setting: Classroom

Activity Type: Learning Cycle

Discipline: Biology

Course: Upper-level Course in Biology

Keywords: gene, promoter, enhancer, transcription factor, coding region, DNA, messenger RNA, protein, RNA polymerase-II, genome equivalence, differential gene expression
Sistem Pendukung Keputusan Pemilihan Rental Mobil dengan Metode Analytical Hierarchy Process (AHP) dan Technique For- Order Preference By Similarity To Ideal Solution (TOPSIS)(Studi Kasus : PT Ravogue Sagara Biru Rental Car Ciamis)
Authors: Maulana Hidayat Cecep , Ruuhwan  , Aso Sudiarjo  
Published: December 2024

Wisatawan dari luar kota atau pun luar negeri sangat membutuhkan jasa driver atau penyewaan mobil untuk melakukan kunjungan selama di Ciamis. Berbagai macam mobil memiliki merk dan teknis yang berbeda, setiap mobil pastinya memiliki kekurangan dan kelebihan. Terdapat kendala yang menjadi penyebab terhadap pemilihan mobil dalam rental mobil yang dimana mobil yang dipilih terkadang tidak sesuai dengan yang konsumen mau. Untuk mengurangi permasalahan ini, maka diperlukan suatu sistem pendukung keputusan untuk membantu konsumen memutuskan mobil yang akan disewa berdasarkan kriteria yang dia inginkan. Pada penelitian ini, menggunakan Sistem Pendukung Keputusan dengan Metode AHP memilih kriteria terbaik berdasarkan bobot yang telah ditentukan. Metode TOPSIS untuk memilih alternatif terbaik dengan perangkingan agar lebih efektif dan efisien tanpa perlu melakukan perhitungan manual. Dengan demikian, penelitian ini memberikan kontribusi dalam pengembangan sistem pendukung keputusan di bidang rental mobil.
Peran Orang Tua Dalam Perkembangan Anak Berkebutuhan Khusus Tuna daksa: Kajian Pastoral Konseling
Authors: Wanget Samuel , Deeker Sumolang  , Mila Enjeli Salindeho  , Meilani Inda Sri Dalending  , Harlinda Losoh Putri Agama  , David Natanael Ponto  
Published: December 2024

Children with special needs are children who are different from children in general. Children with special needs (formerly called extraordinary children) are defined as children who require special education and services to develop their human potential perfectly. Physical disability is one of the limitations for people with special needs and etymologically, physical disability is someone who has difficulty optimizing the function of their body parts as a result of injury, disease, mistreated growth, and as a result the ability to perform certain body movements is impaired. decline. Physical impairment can be defined as a form of abnormality or disability in the muscular and skeletal systems. joints and nerves caused by diseases, viruses and accidents that occur before birth, at birth and after birth. The role of parents in the development of children with special needs, such as disabled children, is very important in pastoral counseling studies. Parents have a role as educators, protectors and caregivers who influence the overall development of children. They must understand and understand the needs of children with special needs and provide appropriate guidance so that children can grow and develop optimally. In pastoral counseling studies, the role of parents also includes building self-confidence in disabled children. Parents must provide strong support and motivation so that children can improve their quality of life and improve their social and academic skills. Apart from that, parents must also understand and understand the self-concept, self-esteem, experience and education that disabled children need to increase their self-confidence.
Neue Anzeige- und Genehmigungspflichten für Unternehmenstransaktionen von Kreditinstituten und anderen Finanzunternehmen
Authors: Brandi Tim Oliver 
Published: December 2024

Zusammenfassung
Das vom EU-Gesetzgeber im Frühsommer 2024 beschlossene Gesetzespaket zur Stärkung der Bankenregulierung führt neue Anzeige- und Genehmigungspflichten für Unternehmenstransaktionen von Kreditinstituten und anderen Finanzunternehmen ein, die bis Januar 2026 in das nationale Recht umzusetzen sind. Hierbei geht es um Beteiligungserwerbe, Verschmelzungen und Spaltungen sowie Vermögensübertragungen durch Kreditinstitute und anderen Finanzunternehmen. Der vorliegende Beitrag stellt diese Neuregelungen vor.
Funktionsverlagerungen nebst Renditekennziffern RoCE, RoS und RoI zur planerischen Verrechnungspreisbestimmung im Rahmen eines APA-Verfahrens — Eine kritische Analyse und Lösungsansätze für die Praxis
Authors: Eymann Stefan , Schneider Markus 
Published: December 2024

Zusammenfassung
Zunehmend geraten Möglichkeiten der Quantifizierung von „Intellectual Property“ (IP) im Rahmen von „klassischen“ Funktionsverlagerungen i.S.d. § 1 Abs. 3b AStG und sonstigen Gewinnchancenverlagerungen in andere Länder - dabei insbesondere in Niedrigsteuerländer - nach dem Kauf inländischer Konzerne und Verrechnungspreisgestaltungen im Rahmen eines „Advance-Pricing-Agreement“-Verfahrens (APA-Verfahren) bei bereits bestehenden APA in den Fokus steuerlicher Auseinandersetzungen. In Einklang damit sind ökonomische Grundsätze zu beachten und die nationale Regelung ist in Übereinstimmung mit dem Verständnis der OECD-Verrechnungspreisleitlinien 2022 zu bringen. Gerade steuerlich gewinnen Marken - ebenso wie andere immaterielle Wirtschaftsgüter - im Zusammenhang mit Konzernzusammenschlüssen eine immer größere Bedeutung in Bezug auf den internationalen Kontext. Die Regelungen des DEMPE-Konzepts (Entwicklung - „development“, Verbesserung - „enhancement“, Erhaltung - „maintenance“, Schutz - „protection“ und Verwertung - „exploitation“) spielen bei der Übernahme von Entrepreneuren ebenso eine wesentliche Rolle, nicht zuletzt aufgrund der klaren nationalen Regelungen des § 1 Abs. 3c AStG. Dieser Beitrag leitet kritikbasiert Fragen zur Funktionsverlagerung i.S.d. § 1 Abs. 3b AStG ab sowie die sich in der Regel anschließende Frage zur Vergütung von Routinefunktionen.
Aktuelle Steuerpolitik
Authors: Wünnemann Monika 
Published: December 2024

Zusammenfassung
Mit dem Bruch der Ampelkoalition ist die Steuerpolitik zunächst zu einem Stillstand gekommen und - abgesehen vom Jahressteuergesetz (JStG) 2024 - werden die aktuellen Gesetzgebungsverfahren voraussichtlich nicht mehr vor der Bundestagswahl 2025 abgeschlossen. Die bisherigen steuerpolitischen Gesetzesinitiativen sind jedoch auch für die neue Legislaturperiode relevant.
LNRRIL6, a novel long noncoding RNA, protects colorectal cancer cells by activating the IL‐6–STAT3 pathway
Authors: Wang Jiaxing , Zhou Junfeng , Jiang Caiyun , Zheng Jing , Namba Hiroki , Chi Pan , Asakawa Tetsuya 
Published: June 2019

Long noncoding RNAs (lncRNAs) are emerging as critical regulators of cancer. There is a comparable number of lncRNAs to protein‐coding genes, but the expression patterns, functions, and molecular mechanisms of most lncRNAs in colorectal cancer (CRC) remain unclear. In this study, we report the identification of a novel lncRNA, named long noncoding RNA regulating IL‐6 transcription (LNRRIL6), which is upregulated in CRC tissues and cell lines. Increased LNRRIL6 expression is associated with aggressive clinicopathological characteristics and poor prognosis of CRC patients. Functional experiments showed that enhanced expression of LNRRIL6 promotes CRC cell proliferation and survival in vitro and CRC tumor growth in vivo. Conversely, depletion of LNRRIL6 inhibits CRC cell proliferation and survival in vitro and CRC tumor growth in vivo. Mechanistically, we revealed that LNRRIL6 physically binds to the IL‐6 promoter, thereby increasing IL‐6 transcription, inducing IL‐6 autocrine signaling, and activating the IL‐6/STAT3 pathway. The expression of IL‐6 is positively associated with that of LNRRIL6 in CRC tissues. Blocking the IL‐6/STAT3 pathway using the FDA‐approved IL‐6‐receptor antagonist antibody, tocilizumab, abolished the oncogenic role of LNRRIL6 in CRC. Taken together, these findings identify a novel lncRNA, LNRRIL6, that promotes CRC cell survival through activation of the IL‐6/STAT3 pathway and suggest that LNRRIL6 may be a potential prognostic biomarker and therapeutic target for CRC.
H
aloterrigena
Authors: Minegishi Hiroaki , Kamekura Masahiro 
Published: June 2019

Abstract

Ha.lo.ter.r'ge.na. Gr. n.
hals
,
halos
the sea, salt; L. fem. adj.
terrigena
born from the earth; N.L. fem. adj.
Haloterrigena
the salt born from the earth.

Euryarchaeota / Halobacteria / Natrialbales / Natrialbaceae / Haloterrigena

The genus
Haloterrigena
consists of 10 species. They are extremely halophilic, with growth occurring in media containing 1.7–5.5 M NaCl. Temperatures between 17 and 60°C support growth. Most strains grow at pH 6.0–9.0, optimally at pH 7.0–7.5, while
Htg. daqingensis
strain JX313 is alkaliphilic growing at pH 8.0–10.5 with optimum at pH 10.0. The major membrane polar lipids are C
20
C
20
and C
20
C
25
glycerol diether derivatives of PG and PGP‐Me. Most strains possess the glycolipid, S2‐DGD‐1 (disulfated diglycosyl diether), while
Htg
.
hispanica
strain FP1 possesses S‐DGD (sulfated diglycosyl diether). Isolates have been recovered from salterns, beach sands, salty soil, and soda lakes.

Before the establishment of the genus
Haloterrigena
in 1999, McGenity et al. (1998) proposed the creation of the new genus
Natrinema
. The two genera overlap to some extent in phylogenetic trees based on 16S rRNA gene sequences. The reclassification of the species presently belonging to the genus
Haloterrigena
as
Natrinema
species may be justified in near future.

DNA G + C content (mol%)
: 59.3–67.0, 61.0–65.4 (genome).

Type species
:
Haloterrigena turkmenica
(Zvyagintseva and Tarasov 1987) Ventosa, Gutiérrez, Kamekura and Dyall‐Smith 1999, 135
VP
(
Halococcus turkmenicus
Zvyagintseva and Tarasov 1987, 843).
D
esulfonauticus
Authors: Galushko Alexander , Kuever Jan 
Published: June 2019

Abstract

De.sul.fo.nau'ti.cus. L. pref.
de
, from; L. masc. n.
sulfur
, sulfur; N.L. pref.
desulfo
‐, desulfuricating, used to characterize a dissimilatory sulfate‐reducing prokaryote; L. masc. adj.
nauticus
, nautical; N.L. masc. n.
Desulfonauticus
, a marine sulfate reducer.

Desulfobacterota / Desulfovibrionia / Desulfovibrionales / Desulfonauticaceae / Desulfonauticus

Cells are curved or straight rods that occur singly or in pairs. Gram‐stain‐negative. Endospores are not observed. Motile. Strict anaerobe with a respiratory type of metabolism. Chemolithoheterotroph or chemolithoautotroph. Substrate specificity depends on the species. Described species of the genus can only use H
2
and formate as electron donors. One species use CO
2
as a carbon source and another species use acetate as additional carbon source. Sulfate, sulfite, thiosulfate, and sulfur are used as terminal electron acceptors and are reduced to H
2
S. The optimal pH range for growth is 7.0–7.8, depending on the species. Moderately thermophilic. The optimal temperature range for growth is between 45 and 58°C. The major menaquinones are partially saturated derivates of menaquinone MK‐6(H
2
). The cellular fatty acids are dominated by anteiso‐ and iso‐C
15
:0
with species‐dependent variations. The genus currently accommodates two species
Desulfonauticus submarinus
and
Desulfonauticus autotrophicus
. Present in high‐temperature habitats such as hydrothermal vents and oil fields.

DNA G + C content (mol%)
: 32.5–41.3 (LC).

Type species
:
Desulfonauticus submarinus
Audiffrin et al. 2003, 1589
VP
.
V
icinamibacter
Authors: Huber Katharina J. , Overmann Jörg 
Published: June 2019

Abstract

Vi.cin.a.mi.bac'ter. L. masc. n.
vicinus
neighbor; L. v.
amare
love; N.L. masc. n.
bacter
a short rod; N.L. masc. n.
Vicinamibacter
rod‐shaped bacterium that loves its neighbor referring to the strong formation of aggregates even during growth in rapidly shaken liquid cultures.

Acidobacteria / ‘Vicinamibacteria’ / ‘Vicinamibacterales’ / Vicinamibacteraceae / Vicinamibacter

The genus
Vicinamibacter
currently comprises one representative that is an aerobic, chemoorganotrophic mesophile and adapted to a broad range of temperature and pH values. Cells stain Gram‐negative and neither form spores nor capsules. The immotile rods divide by binary fission. On agar plates, solid colonies are formed. In liquid culture, cells form tight aggregates, which cannot be disrupted without damaging the cells; single cells might also occur. Cytochrome
c‐
oxidase and catalase activity tests are positive. The single known
Vicinamibacter
species grows on different sugars, organic acids, nucleic acids, and complex proteinaceous compounds. NaCl concentrations up to 1% (w/v) are tolerated. Resistant to ampicillin, carbenicillin, kanamycin, chloramphenicol, erythromycin, tetracycline, and gentamicin and susceptible to spectinomycin and streptomycin. The major fatty acids are iso‐C
17:1
ω9
c
, C
18:1
ω7
c
or ω11
c
, iso‐C
15:0,
summed feature 3 (C
16:1
ω7
c
/C
16:1
ω6
c
), iso‐C
17:0
, and C
16:0
.
Iso
‐diabolic acid and 6‐methyl
iso
‐diabolic are present. Phosphatidylcholine, phosphatidylglycerol, diphosphatidylglycerol, phosphatidylethanolamine, and an unidentified glycolipid are the major polar lipids. MK‐8 is the major quinone. The type strain of the genus
Vicinamibacter
originated from a subtropical savannah riparian woodland soil.

DNA G
+
C content (mol%)
: 65.9 (HPLC).

Type species
:
Vicinamibacter silvestris
Huber, Geppert, Wanner, Fösel, Wüst and Overmann 2016, 2976
VP
.
H
alarsenatibacter
Authors: Oremland Ronald S. , Blum Jodi Switzer , Stolz John F. , Saltikov Chad W. , Lanoil Brian 
Published: June 2019

Abstract

Hal.ar.se.na.ti.bac
'
ter. Gr. n.
hals, halos,
salt, N.L. n.
arsenas, ‐atis
, arsenate, N.L. masc. n.
bacter
, rod; N.L. masc. n.
Halarsenatibacter
, the salty, arsenate‐respiring rod.

Firmicutes / Clostridia / Halanaerobiales / Halanaerobiaceae / Halarsenatibacter

The genus
Halarsenatibacter
is classified into the family
Halanaerobiaceae
, order
Halanaerobiales,
and in the class
Clostridia
. Currently, a single species,
H. silvermanii
, has been described. This haloalkaliphilic, motile bacterium stains Gram‐negative and is shaped as a slightly curved rod.
H. silvermanii
is an obligate anaerobe that uses arsenate, Fe(III), or elemental sulfur as electron acceptors for chemoheterotrophic growth with electron donors such as lactate, pyruvate, malate, and sugars such as galactose, sucrose, and fructose. Fermentative growth was not observed. Chemoautotrophic growth occurs with sulfide as the electron donor and arsenate as the electron acceptor, but cells lack RubisCO activity as the means for CO
2
fixation. The major membrane fatty acids included saturated branched (46%), unsaturated branched (10%), normal saturated (32.5%), and normal unsaturated (11.2%) fatty acids as detailed in Switzer Blum et al. (2009a).

DNA G + C
content (
mol%
): 42.5 as analyzed by HPLC by the DSM.

Type species
:
Halarsenatibacter silvermanii
Switzer Blum, Han, Lanoil, Saltikov, Witte, Tabita et al., 2009b, 1985
VP
(Effective publication: Switzer Blum, Han, Lanoil, Saltikov, Witte, Tabita et al., 2009a, 1959).
Strategies toward High‐Performance Solution‐Processed Lateral Photodetectors
Authors: Lin Tao , Wang Jizheng 
Published: June 2019

AbstractDue to their low cost and ease of integration, solution‐processed lateral photodetectors (PDs) are becoming an important device type among the PD family. In recent years, enormous effort has been devoted to improving their performances, and great achievements have been made. A summary of the core progress, especially from the perspective of design principles and device physics, is necessary to further the development of the field, but is currently lacking. Here, to address this need, first, the working mechanism of PDs and the device figures‐of‐merit are introduced. Second, by classifying the active materials into four categories, including inorganic, organic, hybrid, and perovskite, the developed strategies toward high performance are discussed respectively. To close, the common physical rules behind all these strategies are generalized, and suggestions for future development are given accordingly.