bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous Long‐Persistent Blue Luminescence and High Quantum Yield within 2D Organic–Metal Halide Perovskite Micro/Nanosheets
Authors: Zhou Bo , Yan Dongpeng 
Published: August 2019

AbstractMolecular solid‐state materials with long‐lived luminescence (such as thermally activated delayed fluorescence (TADF) and room temperature phosphorescence (RTP) systems) are promising for display, sensoring, and bio‐imaging applications. However, the design of such materials that exhibit both long luminescent lifetime and high solid‐state emissive efficiency remains an open challenge. Two‐dimensional (2D) organic–metal halide perovskite materials have a high blue‐emitting quantum yield of up to 63.55 % and ultralong TADF lifetime of 103.12 ms at ambient temperature and atmosphere. Our design leverages the combined influences of a 2D space/electronic confinement effect and a modest heavy‐atom tuning strategy. Photophysical studies and calculations reveal that the enhanced quantum yield is due to the rigid laminate structure of perovskites, which can effectively inhibit the non‐radiative decay of excitons.
Modeling the Rheological Behavior of Chemically Interesterified Blends of Palm Stearin/Canola Oil as a Function of Physicochemical Properties
Authors: Saghafi Zahra , Naeli Mohammad Hossein , Tabibiazar Mahnaz , Zargaraan Azizollaah 
Published: August 2019

AbstractThe main aim of the current study was to model the rheological and textural properties of chemically interesterified palm stearin (PS)/canola oil (CO) blends as a function of saturated fatty acids (SFA), solid fat content (SFC), and temperature. The results and proposed models in this study can be used in design and development of new fat products by trying to limit the need for instrumental methods. To describe and predict how the viscoelastic properties and firmness of the blends change with SFA content, several models have been proposed. The firmness curves of fat samples were described as a function of (SFA, Firmness
f(SFA), Rsqr = 0.94, and mean absolute error (MAE) = 1009.00 g) and (SFC20, Firmness
f(SFC20), Rsqr = 0.98, and MAE = 750.80 g) using a one‐variable Quadratic model. In the next step, a two‐variable Quadratic function for expression of firmness as a function of both SFA content and SFC20 with high goodness of fit and low error (Rsqr = 1.00 and MAE = 0.00) was developed. The G′ modulus as a function of temperature (G′
f(T)) and SFC (G'
f(SFC)) curves was S‐shaped and the three Sigmoidal functions (Logistic, Gompertz, and Sigmoid models) were well able to describe their properties. However, the Logistic models described the G′
f(T) (Rsqr>0.99 and MAE < 7838.00 Pa) and G′
f(SFC) (Rsqr>0.94 and MAE < 20,802.00 Pa) curves in the best way. Finally, a two‐variable Logistic model considering both temperature and SFC as variables was developed and fitted on the experimental data with Rsqr of 0.97 and MAE of 85,367.56 Pa. The validation of the proposed models shows their efficiency and ability for prediction of rheological and textural values of various interestrified blends.
Decorating surface charge of graphite nanoplate using an electrostatic coupling agent for 3‐dimensional polymer nanocomposite
Authors: Ryu Seung Han , Kim Seil , Kwon Young‐Tae , Park Young Ki , Kang Sung‐Oong , Cho Hong‐Baek , Choa Yong‐Ho 
Published: August 2019

ABSTRACTHere, we report a facile approach to electrostatically couple the surface charges of graphite nanoplate (GNP) fillers and poly(methyl methacrylate) (PMMA) polymer particles using ethylene maleic anhydride (EMA) copolymer as an electrostatic coupling agent. Our strategy involved switching the intrinsic repulsive electrostatic interactions between the directly exfoliated GNPs fillers and the PMMA particles to attractive electrostatic surface interactions for preparing core(PMMA)‐shell (GNP) precursor in order to optimizing 3‐dimensionally dispersed polymer nanocomposite. As a result, the electrical conductivity of the composites dramatically increased by a factor of 16.7 in the EMA‐coupled GNP/PMMA composites compared with that of the EMA‐free GNP/PMMA composites. In addition, the percolation threshold was also notably reduced from 0.32 to 0.159 vol% after electrostatic coupling of the GNPs fillers and PMMA particles. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48390.
Volatile Oil from Acorus gramineus Ameliorates the Injury Neurons in the Hippocampus of Amyloid Beta 1‐42 Injected Mice
Authors: Gao Ningxin , Liu Hongqing , Li Shiqi , Tu Xing , Tian Sumin , Liu Jing , Li Guoying , Ma Yuxin 
Published: August 2019

ABSTRACTIn recent years, the extraction fraction of volatile oil from Acorus gramineus has significant effects on anti‐dementia and improving the learning and memory of animals. To date, limited studies have determined whether volatile oil from A. gramineus has the protective effect on neuronal damage. The aim of this study was to investigate the protective effects of volatile oil from A. gramineus on Alzheimer's disease (AD) mice, by means of behavior test, immunohistochemistry and western blot methods. In this study, mice were injected with Aβ1‐42 in the bilateral hippocampus to establish the AD model. On the seventh day after modeling, the mice with cognitive dysfunction were selected by the novel object recognition task. Subsequently, the volatile oil treatment groups underwent intragastric administration for per 10 g body weight 2.5 or 5 μL volatile oil from A. gramineus for 3 weeks. The control group and the AD group were given the same amount of saline. Our results showed that after treatment of volatile oil from A. gramineus, the number of Doublecortin and Nestin positive cells increased significantly, suggesting that the volatile oil from A. gramineus may induce the regeneration of hippocampal neurons in mice, and promote the growth of hippocampal neurons by upregulation of brain‐derived neurotrophic factor, tyrosine protein kinase B, and neurotrophin‐3 expression. These results might provide more experimental evidences for underlying mechanism about the neuroprotective effects of volatile oil from A. gramineus against AD relevant symptoms. Anat Rec, 302:2261–2270, 2019. © 2019 American Association for Anatomy
Discovery to solve multidrug resistance: Design, synthesis, and biological evaluation of novel agents
Authors: Qiu Qianqian , Shi Wei , Zhao Shiyuan , Zhu Yan , Ding Zhengquan , Zhou Shaoyang , Kairuki Mutta , Huang Wenlong , Qian Hai 
Published: August 2019

AbstractChemotherapy remains a pillar in the treatment and management of various cancers. However, multidrug resistance (MDR) becomes a severe problem after long‐term administration of chemotherapy drugs. Overexpression of P‐glycoprotein (P‐gp) is a significant cause for tumor MDR. Therefore, P‐gp inhibition is considered as an effective strategy to reverse MDR. A third‐generation P‐gp inhibitor tariquidar was selected as a lead compound, and a new series of triazol‐N‐ethyl tetrahydroisoquinoline based compounds were designed as novel P‐gp inhibitors and synthesized through click chemistry. These compounds presented higher reversal activities than the positive‐control verapamil (VRP). Among 18 compounds, compound 11 without cytotoxicity reversed MDR in a dose‐dependent manner, with a persistent longer chemosensitizing effect and reversibility compared to others. Mechanism studies discovered that compound 11 could escalate the intracellular accumulation of rhodamine‐123 and doxorubicin in K562/A02 cells as well as inhibit their efflux from cells. The results obtained suggest that compound 11 is more potent than VRP administered under the same conditions; it may be a potent and safe candidate for P‐gp modulation for further development.
Effect of quality control on the proliferation of the extract from Taraxacum mongolicum Hand.‐Mazz. in Lactobacillus plantarum
Authors: Liu Jing , Li Xiu‐Mei , Shi Dong‐dong , Wen Zhi‐guo , Yang Pei‐Long 
Published: August 2019

AbstractIn recent years, the fingerprint of high‐performance liquid chromatography has been extensively applied in the identification and quality control of traditional Chinese medicine. It can be a potential protocol for assessing the authenticity, stability and consistency of traditional Chinese medicine and guaranteeing the expected biological activity. In this paper, a method using high‐performance liquid chromatography to identify and control the quality of the extract of Taraxacum mongolicum Hand.‐Mazz. (TME) was established. With this method, the correlation coefficients of the similarity of 10 batches were ≥0.994. The TME displayed a steady proliferative effect in Lactobacillus plantarum. In brief, this study successfully built a reliable, simple and efficient method to control and confirm the quality and the stability of biological activity of the TME.
Immunization strategy for epidemic spreading based on membership (m) over a multilayer network
Authors: Singh Vinay , Verma Pratima , Muthukumaar Vignaesh , Kumar Vimal , Tewari Manuj , Lai Kuei‐Kuei , Chang Yu‐Hsin 
Published: August 2019

AbstractThe purpose of this paper is to declare an immunization strategy for epidemic spreading based on membership (m) of a node among various communities over a multilayer network. The past few years have seen exponential growth in the understanding and research in modern complex networks field. The mapping of real‐world social interactions to complex networks has opened a new pathway for innovation and research. The real‐world interactions among people take place in various circumstances, and thus, a complex network imitates these interactions using various layers. The events and its information in a real world are incorporated in multiple layers in a network that otherwise are lost due to layer aggregation. The form of interaction captured in a multilayer network can have effects of spreading of a process such as an epidemic. The findings explain the highest membership nodes in one layer, immunizing it and observing the propagation of the epidemic through the layers based on a fraction of overlapped nodes in the network that transmit the disease to various layers. Further, this research paper tried to measure the efficiency of the immunization strategy for epidemic spreading based on membership metric when applied on a multilayer network and henceforth apply them to prevent spreading of the rumor/disease. In this manner, the strategy is more productive to secure the people of the entire system.
Chemical Analysis of Selected Seaweeds and Seagrass from the Adriatic Coast of Montenegro
Authors: Milović Sanja , Stanković Ivan , Nikolić Dejan , Radović Jelena , Kolundžić Marina , Nikolić Vesna , Stanojković Tatjana , Petović Slavica , Kundaković‐Vasović Tatjana 
Published: August 2019

AbstractThree seaweeds (Halimeda tuna,Codium bursaandCystoseira barbata) and one seagrass (Cymodocea nodosa) were collected from the Coast of Montenegro, Gulf of Boka Kotorska and their chemical analysis was performed. In seagrassC. nodosa, three phenolic compounds were identified (diosmetin 7‐sulfate, caftaric and coutaric acid). The content ofβ‐glucan, fatty acids, sterols and micro‐ and macro‐elements were investigated among all samples. The highest content ofβ‐glucan was detected inC. nodosaseagrass (13.04±0.42 g/100 g). The highest polyunsaturated fatty acids (PUFAs) level was reported inC. barbata, the brown alga (7.157 mg/g), which also had the significant sterol content (fucosterol, 21.76±0.1 μg/g). Green algae,C. bursaandH. tuna, showed the highest level of sterols (β‐sitosterol, 95.21±0.16 μg/g and 73.90±0.08 μg/g, respectively).H. tunahad the highest content of calcium (Ca) in amount of 55125 μg/g. InC. bursa,C. barbataandC. nodosa, the Na/K ratio was low (0.43, 0.46 and 0.69, respectively).
Multivariate curve resolution methods and the design of experiments
Authors: Sawall Mathias , Kubis Christoph , Schröder Henning , Meinhardt Denise , Selent Detlef , Franke Robert , Brächer Alexander , Börner Armin , Neymeyr Klaus 
Published: August 2019

AbstractA major problem of multivariate curve resolution methods is the underlying non‐uniqueness of the pure component decompositions. This raises the question how a chemical experiment should be designed so that the solution ambiguity is as small as possible. Changes of the reaction conditions belong to the possible variations whereas for a fixed chemical reaction system, the pure component spectra appear to be unchangeable.The paper investigates and discusses the possibility to design a chemical experiment in a way that minimizes the ambiguity of the factorization. The analysis identifies regions of the spectra that are responsible for a small ambiguity. Certain sources are identified that are responsible for an increased ambiguity by means of an a posteriori analysis. This results in recommendations how to construct spectral measurements incorporating a reduced factorization ambiguity. Furthermore, lower bounds on an unavoidable base level of ambiguity are specified under the constraint of fixed reactants. The problem analysis is accompanied by investigations of several experimental data sets.
Organocatalytic Formal Intramolecular [3+2]‐Cycloaddition to Acquire Biologically Important Methanodibenzo[a,f]azulenes and Methanobenzo[f]azulenes
Authors: Peraka Swamy , Pasha Mohammed Anif , Thirupathi Guguloth , Ramachary Dhevalapally B. 
Published: August 2019

AbstractLawsones were transformed into the functionally rich framework of methanodibenzo[a,f]azulenes and methanobenzo[f]azulenes in a single‐ or two‐pot operation through five organocatalytic sequential reactions in very good yields with excellent selectivities. These resultant molecules are basic skeletons of important antibiotics, which highlights the value of this formal intramolecular [3+2]‐cycloaddition as a key protocol.
Oxygen‐Depleted Calixarenes as Ligands for Molecular Models of Galactose Oxidase
Authors: Keck Matthias , Hoof Santina , Herwig Christian , Vigalok Arkadi , Limberg Christian 
Published: August 2019

AbstractA calix[4]arene ligand, in which two of the phenol functions are replaced by pyrazole units has been employed to mimic the His2–Tyr2 (His: histidine, Tyr: tyrosine) ligand sphere within the active site of the galactose oxidase (GO). The calixarene backbone forces the corresponding copper(II) complex into a see‐saw‐type structure, which is hitherto unprecedented in GO modelling chemistry. It undergoes a one‐electron oxidation that is centered at the phenolate donor leading to a copper‐coordinated phenoxyl radical like in the GO. Accordingly, the complex was tested as a functional model and indeed proved capable of oxidizing benzyl alcohol to the respective aldehyde using two phenoxyl‐radical equivalents as oxidants. Finally, the results show that the calixarene platform can be utilized to arrange donor functions to biomimetic binding pockets that allow for the creation of novel types of model compounds.
Experimental methods in chemical engineering: specific surface area and pore size distribution measurements—BET, BJH, and DFT
Authors: Bardestani Raoof , Patience Gregory S. , Kaliaguine Serge 
Published: August 2019

AbstractGas physisorption is an experimental technique based on equilibrium Van der Waals interactions between gas molecules and solid particles, that quantifies the specific surface area (SSA), pore size distribution (PSD), and pore volume of solids and powders. The performance of catalysts, absorbents, chromatography column materials, and polymer resins depends on these morphological properties. Here we introduce the basic principles and procedures of physical adsorption, especially nitrogen physisorption, as a guide to students and researchers unfamiliar with the field. The Brunauer‐Emmett‐Teller theory (BET) is a common approach to estimate SSA that extends the Langmuir monolayer molecular adsorption model to multilayer layers. It relies on an equilibrium adsorption isotherm, measured at the normal boiling point of the adsorbate, eg, 77 K or 87 K for N2 and Ar, respectively. Web of Science indexed 45 400 articles in 2016 and 2017 that mentioned N2 adsorption porosimetry—BET and BJH (Barrett‐Joyner‐Halenda) keywords. The VOSViewer bibliometric tool grouped these articles into four research clusters: adsorption, activated carbon in aqueous solutions for removal of heavy metal ions; synthesis of nanoparticles and composites; catalysts performance in oxidation and reduction processes; and photocatalytic degradation with TiO2. According to the literature, the accuracy of the density function theory (DFT) method is higher than with the BJH theory and it is more reliable.
Comparison of finite volume and lattice Boltzmann methods for multicomponent flow simulations
Authors: Shardt Orest 
Published: August 2019

AbstractIn pseudopotential lattice Boltzmann (LB) models for simulating multicomponent flows, interaction forces between the components of a mixture lead to phase separation and interfacial tension. At the macroscopic scale, such LB models solve an advection‐diffusion equation for each component and the Navier‐Stokes equations for the fluid mixture. In this paper, the computational efficiency of the LB method is compared with a finite volume (FV) solver for the same macroscopic‐scale equations for a binary system in a two dimensional domain. The FV implementation replicates the phase separation of the LB model. Differences in the interfacial tension are due to truncation of the Taylor series expansion of the LB interaction force in the FV version. While the computations required to update the domain for each timestep can be completed faster with the FV approach, a smaller timestep is required to achieve stability, which negates the improvement in processing speed. The FV implementation, however, allows independent variation of model parameters, which is not possible in LB. For example, the viscosity can be changed without affecting interfacial tension or the extent of phase separation. Furthermore, it is possible to obtain low interfacial tensions without suppressing phase separation with the FV formulation. The significance of changing the diffusion rate of components on the deformation of a droplet in shear is also demonstrated. For three‐dimensional simulations, the finite volume approach is expected to be faster than LB and would benefit from the demonstrated flexibility in specifying model parameters.
Upfront autologous hematopoietic stem cell transplantation consolidation for patients with aggressive B‐cell lymphomas in first remission in the rituximab era: A systematic review and meta‐analysis
Authors: Epperla Narendranath , Hamadani Mehdi , Reljic Tea , Kharfan‐Dabaja Mohamed A. , Savani Bipin N. , Kumar Ambuj 
Published: August 2019

BackgroundThe outcomes for patients with diffuse large B‐cell lymphoma (DLBCL) with adverse clinical prognostic factors such as a high age‐adjusted International Prognostic Index (aaIPI) are not optimal. In the current study, the authors performed a systematic review and meta‐analysis to assess the totality of evidence pertaining to the efficacy of autologous hematopoietic stem cell transplantation (auto‐HCT) consolidation for patients with DLBCL in first remission.MethodsThe authors searched the Cochrane and MEDLINE/PubMed databases through December 1, 2018, for studies comparing conventional chemotherapy with rituximab (R‐chemo) versus R‐chemo and auto‐HCT. Two authors independently reviewed all references for study inclusion and extracted data related to benefits (overall survival, progression‐free survival, and response rates) and harms (treatment‐related mortality and adverse events).ResultsFour studies (1173 patients) met the inclusion criteria and were included in the current analysis. The median duration of follow‐up ranged from 42 to 76 months. There was no difference noted with regard to the overall survival (hazard ratio, 1.01; 95% CI, 0.74‐1.37), progression‐free survival (hazard ratio, 0.77; 95% CI, 0.58‐1.04), or response rates (risk ratio, 0.98; 95% CI, 0.92‐1.04) between patients who received R‐chemo and auto‐HCT and those who received R‐chemo alone. The risk of mortality and therapy failure was not found to be different when the analysis was limited to high aaIPI between the 2 groups. Although there was no difference noted with regard to the risk of treatment‐related mortality, there was a significantly higher incidence of CTCAE grade 3 or 4 adverse events in patients who received R‐chemo and auto‐HCT compared with patients treated with R‐chemo alone.ConclusionsThe findings from what to the authors' knowledge is the first meta‐analysis performed in the rituximab era demonstrated no beneficial effect of upfront auto‐HCT consolidation in patients with aggressive B‐cell non‐Hodgkin lymphoma, including high‐risk clinical groups (high aaIPI).
BArt: Trading digital contents through digital assets
Authors: Pérez‐Solà Cristina , Herrera‐Joancomartí Jordi 
Published: August 2019

SummarySince digital artworks are indeed digital content, they face the inherent problem digital content has: the link between content and its original author is very difficult to keep. Additionally, retaining control over digital copies of the content is also a challenging task. Digital coins have solved this very same problem through cryptocurrencies (for instance, Bitcoin) and have opened the door to apply the same techniques to other similar scenarios where ownership of digital assets needs to be preserved. In this paper, we propose BArt, a transparent and distributed mechanism for artists to commercialize their digital artwork, keeping control of the copies, monetizing its usage, and maintaining ownership. BArt allows artists to publicly register their work in the Bitcoin blockchain and sell usage rights in exchange for bitcoins. Buyers are allowed to exert the acquired rights. Proper behavior from all parties is enforced by the system with cryptography and economic incentives.
Signal and reward in wild fleshy fruits: Does fruit scent predict nutrient content?
Authors: Nevo Omer , Razafimandimby Diary , Valenta Kim , Jeffrey Juan Antonio James , Reisdorff Christoph , Chapman Colin A. , Ganzhorn Jörg U. , Ayasse Manfred 
Published: August 2019

Abstract

Plant species with fleshy fruits offer animals rewards such as sugar, protein, and fat, to feed on their fruits and disperse their seeds. They have also evolved visual and olfactory signals indicating their presence and ripeness.
In some systems, fruit color serves as a reliable visual signal of nutrient content. Yet even though many volatile chemicals used as olfactory signals derive from nutrients animals seek, it is still unknown whether fruit scent encodes information regarding nutrient content in wild fruits.
We examine the relationship between olfactory signals and nutrient rewards in 28 fruiting plant species in Madagascar. We measured the relative amounts of four chemical classes in fruit scent using gas chromatography and mass spectrometry, as well as the relative amounts of sugar and protein in fruit pulp.
We found that protein levels are not associated with elevated amounts of chemically related volatile compounds in fruit scent. In contrast, sugar content is strongly associated with the chemical composition of fruit scent.
To our knowledge, this is the first research to explore the connection between fruit chemical signals and nutrient rewards. Our results imply that in the case of sugar, fruit scent is predictive of nutrient content and hence an honest signal.