bluuebunny/crossref_metadata_2025_split huggingface dataset:
A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis
Authors: Takahashi Naoki , Ogita Nobuo , Takahashi Tomonobu , Taniguchi Shoji , Tanaka Maho , Seki Motoaki , Umeda Masaaki 
Published: December 2018

AbstractCell cycle arrest is an active response to stresses that enables organisms to survive under fluctuating environmental conditions. While signalling pathways that inhibit cell cycle progression have been elucidated, the putative core module orchestrating cell cycle arrest in response to various stresses is still elusive. Here we report that in Arabidopsis thaliana, the NAC-type transcription factors ANAC044 and ANAC085 are required for DNA damage-induced G2 arrest. Under genotoxic stress conditions, ANAC044 and ANAC085 enhance protein accumulation of the R1R2R3-type Myb transcription factor (Rep-MYB), which represses G2/M-specific genes. ANAC044/ANAC085-dependent accumulation of Rep-MYB and cell cycle arrest are also observed in the response to heat stress that causes G2 arrest, but not to osmotic stress that retards G1 progression. These results suggest that plants deploy the ANAC044/ANAC085-mediated signalling module as a hub which perceives distinct stress signals and leads to G2 arrest.
Starbucks: global brand in emerging markets
Authors: Gupta Praveen , Nagpal Ankita , Malik Diksha 
Published: December 2018

Learning outcomes
Students after reading the case will learn about the issues and challenges of expansion in emerging markets. Global expansion versus multinational expansion. Stardardization versus localization. Socio-cultural aspects in international marketing. Leadership succession in multinational companies.

Case overview/synopsis
The case is about Starbucks’ journey of global expansion. It focuses on challenges in emerging markets. It also talks about the challenges to new CEO Kevin Johnson post stepping down of iconic leader Howard Schultz.

Complexity academic level
MBA Executive MBA Specialisation in Strategy, International Marketing.

Supplementary materials
Teaching Note are available for educators only. Please contact your library to gain login details or email support@emeraldinsight.com to request teaching notes.

Subject code
CSS 5: International Business.
Psychological antecedents of apparel-buying intention for young Indian online shoppers
Authors: Singh Vinita , Chaudhuri Ranjan , Verma Sanjeev 
Published: December 2018

Purpose
This paper aims to determine a scale for measuring psychological factors of apparel-buying intention for young Indian online shoppers.

Design/methodology/approach
Churchill’s three-stage systematic scale-development methodology is used to develop a psychometric scale. Items were generated and selected in Phase I, followed by scale refinement in Phase II and scale validation in Phase III.

Findings
The final scientifically validated scale has 36 item scales that measure 10 psychological factors of apparel online-buying intention for online shoppers, from which “perceived value” emerged as the most significant factor.

Research limitations/implications
This scale is a sector-specific scale that cannot be generalized to other sectors; therefore, further iterations/customizations should be made in future studies for applicability in other sectors.

Practical implications
This reliable and valid scale will help marketing managers to understand online shopper behavior and formulate effective strategies for online shoppers.

Originality/value
This paper, to the author’s knowledge, is the first attempt to develop a validated tool to measure the psychological factors of apparel-buying intention for young Indian online shoppers. This scale encompasses all important touch-points in measuring psychological factors influencing online buyer behavior for apparel products.
Development of metaheuristics to solve a transportation inventory location routing problem considering lost sale for perishable goods
Authors: Fatemi Ghomi S.M.T. , Asgarian B. 
Published: December 2018

PurposeFinding a rational approach to maintain a freshness of foods and perishable goods and saving their intrinsic attributes during a distribution of these products is one of the main issues for distribution and logistics companies. This paper aims to provide a framework for distribution of perishable goods which can be applied for real life situations.Design/methodology/approachThis paper proposes a novel mathematical model for transportation inventory location routing problem. In addition, the paper addresses the impact of perishable goods age on the demand of final customers. The model is optimally solved for small- and medium-scale problems. Moreover, regarding to NP-hard nature of the proposed model, two simple and one hybrid metaheuristic algorithms are developed to cope with the complexity of problem in large scale problems.FindingsNumerical examples with different scenarios and sensitivity analysis are conducted to investigate the performance of proposed algorithms and impacts of important parameters on optimal solutions. The results show the acceptable performance of proposed algorithms.Originality/valueThe authors formulate a novel mathematical model which can be applicable in perishable goods distribution systems In this regard, the authors consider lost sale which is proportional to age of products. A new hybrid approach is applied to tackle the problem and the results show the rational performance of the algorithm.
Does corporate social responsibility really increase customer relationship quality? A meta-analytic review
Authors: Aljarah Ahmad , Emeagwali Lawrence , Ibrahim Blend , Ababneh Bashar 
Published: December 2018

PurposeThe purpose of this paper is to examine the impact of corporate social responsibility (CSR) on customer relationship quality (RQ) based on three main aspects of RQ, namely, satisfaction, trust and commitment.Design/methodology/approachA quantitative meta-analysis of 80 unique effect sizes reported in 60 articles (n= 27,805) was conducted to determine effect sizes of the relationship between CSR and the aspects of RQ of the customer. Furthermore, the economic development has been examined as potential moderators between CSR and RQ.FindingsMeta-analysis suggests that a positive relationship between CSR and the three studied aspects of RQ is well established; however, the strength of studied relationships has revealed variations in magnitude. Customer commitment was affected by CSR (r= 56) the most, closely followed by customer trust (r= 0.52), while customer satisfaction (r= 0.44) was affected the least. Moreover, the result of meta-regression shows that the economic development moderates only one relationship, CSR and trust.Originality/valuePresenting a summary of the direction of primary research on the relationship between CSR and RQ, as no prior meta-analysis on the primary relationship has been conducted till date (to the best of the authors’ knowledge).
Linear Viscoelastic Properties of Selected Polysaccharide Gums as Function of Concentration, pH, and Temperature
Authors: Fagioli Laura , Pavoni Lucia , Logrippo Serena , Pelucchini Caroline , Rampoldi Luca , Cespi Marco , Bonacucina Giulia , Casettari Luca 
Published: December 2018

AbstractHydrocolloids have been intensively investigated due to their ability to modify the rheology of the system where they are employed. They find application as thickening and gelling agents in many food, cosmetic, and pharmaceutical preparations, due to their biocompatibility and biodegradability. The present study aims to provide an exhaustive and comprehensive viscoelastic characterization of a series of hydrocolloid formulations, as function of concentration, pH, and temperature. Glucomannan, xanthan gum, tara gum, guar gum, konjac gum, and gellan gum have been analyzed at two concentrations (0.5% w/w and 1.5% w/w), using three different pH conditions (pH 1.2, 5.5, and 6.8). Their viscoelastic properties have been monitored measuring the main rheological parameters, namely, storage modulus G′ and loss modulus G′′ as function of frequency, time, and temperature. The results obtained show a clear dependence of the linear viscoelastic properties of the systems on concentration and pH, while the temperature was not a critical factor. Glucomannan, xanthan gum, tara gum, and guar gum samples prepared in phosphate buffer (pH 6.8) at the final concentration of 1.5% (w/w) have been selected as the most promising systems for further investigations, exploring the possibility of combinations to improve the rheological properties.Practical ApplicationGlucomannan, xanthan gum, tara gum, guar gum, konjac gum, and gellan gum have been chosen among the most common thickening agents derived from plants to perform a systematic investigation of the influence of pH, concentration, and temperature on the rheological properties of their water dispersions. The data obtained may be useful for further application of these hydrogels in the nutraceutical field as thickeners, texture modifiers, emulsifiers, stabilizers, and gelling agents.
Effects of grafting on host plant resistance in ash (Fraxinusspp.) to emerald ash borer (Agrilus planipennisFairmaire)
Authors: Stack Sara C. , Sadof Clifford S. , Ginzel Matthew D. 
Published: December 2018

AbstractThe invasive emerald ash borer (EAB) (Agrilus planipennisFairmaire Coleoptera: Buprestidae) is a phloem‐boring pest from Asia that has killed hundreds of millions of North American ash trees (Fraxinusspp.). Propagation of trees resistant to EAB must be explored as a tool to maintain the North American ash resource.Interactions between the root and shoot of a tree may be critical to its ability to resist attack by insects and pathogens because many secondary metabolites critical to plant defence are synthesized in the roots.In the present study, we determined the extent to which grafting susceptible green ash (Fraxinus pennsylvanicaMarshall) and resistant Manchurian ash (Fraxinus mandshuricaRupr.) affects EAB resistance in ash trees. We measured adult EAB survivorship, herbivory, fecundity and morphological tree characteristics on grafted and nongrafted green and Manchurian ash.Among grafted trees, beetles caged on grafted green ash lived four days longer and laid at least three times more eggs than beetles caged on trees with a Manchurian ash scion or rootstock. Herbivory was unaffected by graft combination.Our findings suggest that grafted trees with Manchurian ash rootstocks or scions will be more resistant to EAB than nongrafted green ash trees.
Audit Quality in New Zealand – Early Evidence from the Regulator
Authors: Rainsbury Elizabeth A. 
Published: December 2018

AbstractThis study examines the impact of audit regulation in New Zealand, using audit quality reviews undertaken by the Financial Markets Authority (FMA) between 2013 and 2017. Regulation has more than halved the number of registered audit firms indicating that it imposes costs on audit firms. The results show that audit quality is improving, but a high proportion of audits do not meet the FMA's requirements. A key area for improvement is the consistency of quality across audits performed by the same audit firm. The FMA advises audit firms to investigate the underlying cause of audit deficiencies to ensure that internal quality control systems are effective in producing high‐quality audits on a regular basis. A comparison of audit file ratings with the United Kingdom shows that New Zealand's audit quality is much lower. The variation in audit quality across countries concerns the International Forum of Independent Audit Regulators (IFIAR) as it has the potential to undermine stakeholder confidence in the audit industry. Thus monitoring progress in improving audit quality in New Zealand is important. This paper provides insights into audit quality at a country level, whereas most research focuses on the firm level.
Novel GLI2 mutations identified in patients with Combined Pituitary Hormone Deficiency (CPHD): Evidence for a pathogenic effect by functional characterization
Authors: Babu Deepak , Fanelli Antonella , Mellone Simona , Muniswamy Ranjith , Wasniewska Malgorzata , Prodam Flavia , Petri Antonella , Bellone Simonetta , Salerno Maria Carolina , Giordano Mara 
Published: December 2018

SummaryContextThe Gli‐family of zinc‐finger transcription factors regulates the Sonic Hedgehog (Shh) signalling pathway that plays a key role in early pituitary and ventral forebrain development. Heterozygous GLI2 loss of function mutations in humans have been reported in holoprosencephaly (HPE), HPE‐like phenotypes associated with pituitary anomalies and combined pituitary hormone deficiency with or without other extra‐pituitary findings.ObjectiveThe aim of this study was the search for GLI2 mutations in a cohort of Italian CPHD patients and the assessment of a pathogenic role for the identified variants through in vitro studies.PatientsOne hundred forty‐five unrelated CPHD patients diagnosed with or without extra‐pituitary manifestations were recruited from different Italian centres.MethodsThe GLI2 mutation screening was carried out through direct sequencing of all the 13 exons and intron‐exon boundaries. Luciferase reporter assays were performed to evaluate the role of the detected missense variants.ResultsFive different novel heterozygous non‐synonymous GLI2 variants were identified in five patients. The mutations were three missense (p.Pro386Leu, p.Tyr575His, p.Ala593Val), one frameshift (p.Val1111Glyfs*19) and one nonsense (p.Arg1226X). The latter two mutants are likely pathogenic since they lead to a truncated protein. The in vitro functional study of the plasmids bearing two of the three missense variants (namely p.Tyr575His and p.Ala593Val) revealed a significant reduction in transcriptional activity.ConclusionIn conclusion, the analysis of GLI2 in individuals with CPHD led to the identification of five variations with a likely negative impact on the GLI2 protein, confirming that GLI2 is an important causative gene in CPHD. The functional in vitro study analysis performed on the missense variations were useful to strengthen the hypothesis of pathogenicity.
What drives at‐risk species richness? Environmental factors are more influential than anthropogenic factors or biological traits
Authors: Howard Christine , Flather Curtis H. , Stephens Philip A. 
Published: December 2018

AbstractSpecies at risk of extinction are not uniformly distributed in space. Concentrations of threatened species may occur where threatening processes are intense, in refuges from those processes, or in areas of high species diversity. However, there have been few attempts to identify the processes that explain the distribution of at‐risk species. Here, we identified the relative importance of biological traits, environmental factors, and anthropogenic stressors in driving the spatial patterns of both total and at‐risk species richness of North American mammals and birds. Environmental factors are the predominant drivers of both total and at‐risk species richness. Strikingly, the directions of variable relationships differ substantially between models of total and at‐risk species richness. Understanding how environmental gradients differentially drive variation in total and at‐risk species richness can inform conservation action. Moreover, our approach can predict shifts in at‐risk species concentrations in response to projected environmental change and anthropogenic stressors.
Hypertrophic cardiomyopathy with dynamic obstruction and high left ventricular outflow gradients associated with paradoxical apical ballooning
Authors: Sherrid Mark V. , Riedy Katherine , Rosenzweig Barry , Ahluwalia Monica , Arabadjian Milla , Saric Muhamed , Balaram Sandhya , Swistel Daniel G. , Reynolds Harmony R. , Kim Bette 
Published: December 2018

BackgroundAcute left ventricular (LV) apical ballooning with normal coronary angiography occurs rarely in obstructive hypertrophic cardiomyopathy (OHCM); it may be associated with severe hemodynamic instability.Methods, ResultsWe searched for acute LV ballooning with apical hypokinesia/akinesia in databases of two HCM treatment programs. Diagnosis of OHCM was made by conventional criteria of LV hypertrophy in the absence of a clinical cause for hypertrophy and mitral‐septal contact. Among 1519 patients, we observed acute LV ballooning in 13 (0.9%), associated with dynamic left ventricular outflow tract (LVOT) obstruction and high gradients, 92 ± 37 mm Hg, 10 female (77%), age 64 ± 7 years, LVEF 31.6 ± 10%. Septal hypertrophy was mild compared to that of the rest of our HCM cohort, 15 vs 20 mm (P < 0.00001). An elongated anterior mitral leaflet or anteriorly displaced papillary muscles occurred in 77%. Course was complicated by cardiogenic shock and heart failure in 5, and refractory heart failure in 1. High‐dose beta‐blockade was the mainstay of therapy. Three patients required urgent surgical relief of LVOT obstruction, 2 for refractory cardiogenic shock, and one for refractory heart failure. In the three patients, surgery immediately normalized refractory severe LV dysfunction, and immediately reversed cardiogenic shock and heart failure. All have normal LV systolic function at 45‐month follow‐up, and all have survived.ConclusionsAcute LV apical ballooning, associated with high dynamic LVOT gradients, may punctuate the course of obstructive HCM. The syndrome is important to recognize on echocardiography because it may be associated with profound reversible LV decompensation.
Direct and indirect effects of climate on richness drive the latitudinal diversity gradient in forest trees
Authors: Chu Chengjin , Lutz James A. , Král Kamil , Vrška Tomáš , Yin Xue , Myers Jonathan A. , Abiem Iveren , Alonso Alfonso , Bourg Norm , Burslem David F.R.P. , Cao Min , Chapman Hazel , Condit Richard , Fang Suqin , Fischer Gunter A. , Gao Lianming , Hao Zhanqin , Hau Billy C.H. , He Qing , Hector Andrew , Hubbell Stephen P. , Jiang Mingxi , Jin Guangze , Kenfack David , Lai Jiangshan , Li Buhang , Li Xiankun , Li Yide , Lian Juyu , Lin Luxiang , Liu Yankun , Liu Yu , Luo Yahuang , Ma Keping , McShea William , Memiaghe Hervé , Mi Xiangcheng , Ni Ming , O'Brien Michael J. , de Oliveira Alexandre A. , Orwig David A. , Parker Geoffrey G. , Qiao Xiujuan , Ren Haibao , Reynolds Glen , Sang Weiguo , Shen Guochun , Su Zhiyao , Sui Xinghua , Sun I‐Fang , Tian Songyan , Wang Bin , Wang Xihua , Wang Xugao , Wang Youshi , Weiblen George D. , Wen Shujun , Xi Nianxun , Xiang Wusheng , Xu Han , Xu Kun , Ye Wanhui , Zhang Bingwei , Zhang Jiaxin , Zhang Xiaotong , Zhang Yingming , Zhu Kai , Zimmerman Jess , Storch David , Baltzer Jennifer L. , Anderson‐Teixeira Kristina J. , Mittelbach Gary G. , He Fangliang 
Published: December 2018

AbstractClimate is widely recognised as an important determinant of the latitudinal diversity gradient. However, most existing studies make no distinction between direct and indirect effects of climate, which substantially hinders our understanding of how climate constrains biodiversity globally. Using data from 35 large forest plots, we test hypothesised relationships amongst climate, topography, forest structural attributes (stem abundance, tree size variation and stand basal area) and tree species richness to better understand drivers of latitudinal tree diversity patterns. Climate influences tree richness both directly, with more species in warm, moist, aseasonal climates and indirectly, with more species at higher stem abundance. These results imply direct limitation of species diversity by climatic stress and more rapid (co‐)evolution and narrower niche partitioning in warm climates. They also support the idea that increased numbers of individuals associated with high primary productivity are partitioned to support a greater number of species.
The strength of ecological subsidies across ecosystems: a latitudinal gradient of direct and indirect impacts on food webs
Authors: Montagano Laurent , Leroux Shawn J. , Giroux Marie‐Andrée , Lecomte Nicolas 
Published: December 2018

AbstractMaterial and energy flows among ecosystems can directly and indirectly drive ecosystem functions. Yet, how populations of consumers respond to allochthonous inputs at a macroecological scale is still unclear. Using a meta‐analysis spanning several biomes, we show that the abundance of recipient populations is 36–57% larger with increased allochthonous inputs. The strength of direct effects on the recipients of these inputs as well as the indirect effects on the consumers of these recipients (i.e. ascending indirect effects) are constant across a latitudinal gradient spanning subtropical, arid, temperate, boreal and arctic ecosystems. However, indirect effect on the in situ resources of the input recipient (i.e. descending indirect effects) decreases with latitude. Our results suggest that the influence of allochthonous inputs can vary across large‐scale gradients of ecosystem productivity and may be driven by the types of trophic interactions within recipient food webs.
Ipomoea triloba: an alien plant threatening many habitats in Turkey
Authors: Yazlik A. , Üremiş İ. , Uludağ A. , Uzun K. , Şenol S. G. 
Published: December 2018

Ipomoea triloba is a plant native to tropical America and has been observed in cotton fields in Antalya Province, Turkey. Ipomoea triloba was identified in 2014 after a warning from the Centre of the Farmers’ Union (Antbirlik). Subsequent field surveys showed that this plant has been considered as a weed by farmers in this region for the last two decades; it has spread in non‐agricultural habitats but due to its limited presence did not receive much attention. The spread of I. triloba has increased over the last 5 years to such an extent that it cannot be controlled by existing methods including herbicides. It has established not only in agricultural areas but also in other habitats such as roadsides, irrigation channel edges and coastal regions. This paper provides the first botanical description report of I. triloba in the defined area, an evaluation of environmental and socioeconomic impacts, current status and management activities. Based on all available information the authors concluded that pest risk analysis should be conducted on I. triloba. Furthermore, it should be regarded not only as an environmental weed but also as an agricultural weed and kept under surveillance in Turkey.
Isolation and culture of human primary keratinocytes—a methods review
Authors: Ścieżyńska Aneta , Nogowska Aleksandra , Sikorska Maria , Konys Justyna , Karpińska Anita , Komorowski Michał , Ołdak Monika , Malejczyk Jacek 
Published: December 2018

AbstractKeratinocyte culture is a necessary and widely used tool in a variety of experimental dermatological and biomedical studies. Literature search has revealed a variety of different protocols of human primary keratinocyte isolation and culture. Therefore, the aim of this paper was to review and summarize current trends in human primary keratinocyte culture techniques. We present data on the most popular and effective methods of human keratinocyte isolation and cultivation obtained from screening of 945 papers published during the last 10 years.