bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural Vulnerability Factors and Gestational Weight Gain: A Scoping Review on the Extent, Range, and Nature of the Literature
Authors: Labonté Jocelyne M , Dumas Alex , Clark Emily , Savard Claudia , Fournier Karine , O’Connor Sarah , Morisset Anne-Sophie , Fontaine-Bisson Bénédicte 
Published: October 2024

Abstract

Background: Inadequate and excessive gestational weight gain (GWG) are rising epidemiological health concerns, affecting a substantial proportion of pregnant women in high-income countries and contributing to a multitude of adverse maternal and infant health outcomes. The aim of this scoping review was to identify key structural vulnerability factors (SVFs) related to GWG, and to examine the extent, range, and nature of the existing literature to inform future research.
Methods: Electronic searches were performed in October 2018 (updated in August 2019) in MEDLINE(R) ALL, EMBASE, PsycINFO, CINAHL, and Sociological Abstracts databases. Eligible studies had an observational design, had to be conducted before COVID-19, in a high-income country, have pregnant participants, and perform inferential statistics between an SVF and GWG.
Results: Of the 157 included articles, the eight SVFs most commonly studied in association with GWG were race/ethnicity (n=91 articles), age (n=87), parity (n=48), education (n=44), income (n=39), marital status (n=28), immigration (n=19), and abuse (n=12). Substantialheterogeneity across study contexts, methodologies, populations, and findings was identified. Studies spanned 22 high-income countries, were predominantly conducted in the USA (77%), and most studies (60%) had a retrospective design. Race/ethnicity was the most extensively studied factor, covering the longest time period (since 1976) and having the largest sample size, and the second-highest proportion of studies reporting a significant relationship with GWG (79%), following immigration status (95%).
Conclusions: Given the heterogeneity in findings across studies, adopting an intersectional approach may enhance our understanding of the complex interplay between SVFs and the social context in relation to GWG. This nuanced perspective is critical for informing future research and developing effective strategies to address the pervasive perinatal health challenges associated with inadequate and excessive GWG.
Genomic insight into X chromosome dynamics in high altitude adaptation of trans-Himalayan yaks
Authors: Dige Mahesh Shivanand , Mahar Karan , Goli Rangasai Chandra , Gurao Ankita , Kumar Amod , Chitkara Meenakshi , Jagadeeesan K , Ahlawat Sonika , Niranjan Saket Kumar , Pundir Rakesh Kumar , Arora Reena , Kataria Ranjit Singh 
Published: October 2024

Abstract

This study delves into the genomic foundations of high-altitude adaptation in Indian yaks, with a specific emphasis on the X chromosome and its role in traits related to production, reproduction, and immunity. Utilizing whole-genome resequencing, we identified 319,015 high-quality X chromosomal SNPs from 30 unrelated Indian yaks and 8 Jinchuan yaks. These SNPs were analyzed through various statistical methodologies, including composite likelihood ratio (CLR) statistics, Tajima’s D, iHS, FST, and XP-EHH. Our findings highlight several genes associated with high-altitude adaptation, such as AIFM1, APOOL, ATRX, CHST7, DACH2, DGAT2L6, DIAPH2, and EIF2S3B, identified through iHS, Tajima’s D, and CLR approaches. Additionally, genes including GPR119, HS6ST2, MAGED1, MOSPD1, PQBP1, SLC25A14, SLC35A2, TIMM17B, and WDR44 exhibited common selection signatures across FST and XP-EHH methods. Unique genes and loci specific to each yak population were uncovered on the X chromosome, which are critical for adaptability, immunity, reproduction, and production traits. Notably, our study identified selection regions containing the RLIM gene in Himachali yaks, which is crucial for Dosage Compensation on the X chromosome. This research offers new insights into X-linked selection across different yak populations, enhancing our understanding of the genomic mechanisms underlying high-altitude adaptation.
Asymptomatic school-aged children carry the majority of transmissible Plasmodium falciparum infections
Authors: Buchwald Andrea , Vareta Jimmy , Nwagbata Otutochukwu , McCann Robert , Sixpence Alick , Matengeni Alfred , Kamzati Moses , Mangani Charles , seydel karl , Wilson Mark , Taylor Terrie , Mathanga Don , Valim Clarissa , Laufer Miriam , Cohee Lauren 
Published: October 2024

Abstract

Persistent human-to-mosquito parasite transmission hinders malaria control in high burden settings. Understanding the human transmission reservoir can support the design of targeted interventions to reduce transmission. In a year-long cohort study in rural Malawi, we used molecular methods to detect all Plasmodium falciparum (Pf) infections and those containing gametocytes, the parasite stage required for transmission, longitudinally at routine surveillance and sick visits. Using population-level analyses, we determined the demographic, temporal, and spatial clustering of infections containing gametocytes and gametocyte density, which predicts transmission. Gametocytes were not randomly distributed among the population or among individuals with Pf infections; gametocytes were detected in only 23% of the population. Among all participants, school-age children had significantly higher incidence of gametocyte-containing infections and high-density gametocyte infections compared to other groups. The presence of school-age children was a key driver of gametocyte frequencies and densities within households, even after adjusting for Pf infection levels. Based on the total gametocyte abundance in the population, we estimate that clearing infections from asymptomatic school-age children in the rainy season would decrease gametocyte abundance by 67% in the population. Thus, interventions targeting school-age children are needed to effectively reduce Pf infection risk at a population level.
Sustained Anxiolytic-Like Effects of N-Acetylcysteine in Zebrafish Subjected to Unpredictable Chronic Stress
Authors: Mocelin Ricieri , Peroni Bruno Zilli 
Published: October 2024

Abstract

Introduction: Mental disorders such as anxiety and depression are highly prevalent in today's society, representing a public health issue that causes deleterious effects on individuals and healthcare systems. Despite their significance, there are currently no highly effective, sustained-acting medications with minimal adverse effects available, highlighting the need for new pharmacological options.
Objective: To investigate the sustained effect of N-acetylcysteine (NAC) on behavioral parameters in zebrafish subjected to an unpredictable chronic stress (UCS) protocol.
Methodology:Eighty zebrafish were allocated into eight experimental groups, with 10 animals each. Four of the groups were subjected to UCS (+), and four were not (-). Each of these four groups was exposed to either N-acetylcysteine (NAC, 10 mg/L, 20 min), Fluoxetine (FLU, 10 mg/L, 20 min), Ketamine (KET, 20 mg/L, 20 min), or a control solution (CTRL, water, 20 min). During the first seven days, the animals were exposed to the UCS protocol. On the 7th day, they received their respective pharmacological treatments (CTRL, NAC, FLU, or KET). After 24 hours of treatment exposure (day 8), the animals were subjected to the novel tank test, where the following parameters were evaluated: distance traveled (m); number of crossings; and time spent in the upper and lower areas (s).
Results: UCS reduced the number of crossings and time spent in the upper area and increased the time spent in the lower area. All treatments (NAC, FLU, and KET) were able to mitigate the anxiogenic-like effect induced by UCS. Additionally, FLU exhibited anxiolytic-like behavior in animals not subjected to UCS.
Conclusions:Considering the sustained effect of NAC in reversing the anxiogenic effect induced by stress, its good safety and tolerability profile in humans, as well as its low cost, this study reinforces the applicability of NAC in stress-related neuropsychiatric disorders.
Performance and reliability of solder joints in dual nanometer Cu6Sn5 and Ag3Sn particle-doped modified Sn3.0Ag0.5Cu composite solders
Authors: Wang Biao , Li Xiu , Xu Jiayi , zhao jian , Yan Jikang 
Published: October 2024

Abstract

In this study, Ag3Sn and Cu6Sn5 nanoparticles were synthesized using the redox method, and SAC305-0.15Ag3Sn-xCu6Sn5 (x = 0 wt%, 0.05 wt%, 0.1 wt%, 0.15 wt%, and 0.2 wt%) composite solder was produced by incorporating these nanoparticles into Sn-3.0Ag-0.5Cu (SAC305) solder. The thermal properties, wettability, microstructure, Vickers hardness, tensile strength, and reliability of the solder joints in these composite solders were systematically investigated. The results demonstrated that the melting point of the composite solder increased upon the addition of dual nanoparticles to the SAC305 solder. The incorporation of Ag3Sn nanoparticles and an appropriate amount of Cu6Sn5 nanoparticles inhibited the excessive growth of intermetallic compounds (IMC) within the solder alloy matrix and refined the alloy microstructure. Additionally, the wettability of the solder alloy improved, with the spreading area of SAC305-0.15Ag3Sn-0.15Cu6Sn5 composite solder reaching 88.5565 mm², which is 8.50% higher than that of SAC305-0.15Ag3Sn solder. Mechanical property analysis revealed that the solder alloy containing dual nanoparticles exhibited higher Vickers hardness and tensile strength in the solder joints, with maximum values of 12.02 HV and 56.68 MPa, respectively. Aging tests indicated that the addition of dual nanoparticles inhibited the growth of the interfacial IMC layer and reduced the growth coefficient, with a minimum value of 0.0180.
Interest of data augmentation in AI-prediction of metal laser welding penetration
Authors: HAYOT Victor , AMHAZ Rabih , LECLER Sylvain , Ferreira Andre Alves , Chabrol Grégoire 
Published: October 2024

Abstract

Used in industries such as automobiles and aeronautics, metal laser welding remains a challenging process to master. It is characterised by its high penetration/width ratio, useful when the weld is realised through a material. As the result of a physical transformation involving non-linear laser-matter interaction, thermodynamic and fluid mechanic, it possesses numerous interactions between its parameters, making it a poor candidate for simulation or Design of Experiment modelling. The main method to get the production-ready set of parameters remains the time-consuming and labour-intensive trial and error. In this study, Artificial Intelligence is investigated on readily available data from previous trials to predict weld penetration. We found that feature engineering, and especially data augmentations, significantly improves the prediction. Tested in challenging situations, the model highlighted its abilities both in interpolation and extrapolation on most of the unstudied materials. Such a model could be used to identify the set of parameters able to achieve a given laser weld penetration in new metals.
Detecting Deception: Employing Deep Neural Networks for Fraudulent Review Detection on Amazon
Authors: Jayasinghe J.M. Thilini , Dassanayaka Sachith 
Published: October 2024

Abstract

In the era of e-commerce dominance, an increase in fake reviews on online shopping platforms compromises the integrity of consumer feedback systems. This study focuses on Amazon, a leading e-commerce platform in the United States, where fake reviews have become a significant concern. Given the limited availability of authentic datasets for analysis, we propose a novel methodology to differentiate between genuine and fraudulent reviews across verified and non-verified purchases. Our approach utilizes the bootstrap distribution of cosine similarity values, providing a robust statistical foundation for review classification. We present a comprehensive framework integrating Convolutional Neural Networks with word embedding and emotion-mining techniques through Natural Language Processing. This multifaceted approach enhances detection accuracy and offers insights into the linguistic and emotional markers of fake reviews. Our method demonstrates exceptional performance, achieving an accuracy rate of over 96\% in distinguishing fake reviews from user reviews. This study contributes to the growing research on online review authenticity and offers practical implications for e-commerce platforms, regulatory bodies, and consumers. This research aims to foster trust in online marketplaces and protect consumers from misleading information by providing a powerful tool for fake review detection.
Analysis of Intrathecal Labor Analgesia and the Causes of Maternal Postpartum Depression After Cesarean Section
Authors: Xu Xiaomei , Yang Ming , Ji Haoyu , Gao Pengfei , Qiu Cheng , Xia Xiaoqiong , Li Yuanhai 
Published: October 2024

Abstract

BACKGROUND: Postpartum depression (PPD) is a common complication after childbirth, and its etiology may be related to several factors. In this study, we investigated the prevalence and causes of PPD in women who underwent vaginal delivery with intrathecal labor analgesia and women who underwent cesarean section.
METHODS: A total of 242 women who gave birth from July 2022to July 2023 participated in this retrospective case‒control study, including 127 women who underwent cesarean section and 115 women who underwent vaginal delivery and received intrathecal labor analgesia. The clinical data of the study participants were collected, and anxiety, depression and PPD were assessed by the Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) and the Chinese version of the Edinburgh Postnatal Depression Scale (EPDS); questionnaires were administered and telephone follow-up was conducted on the first day of the antenatal period. The Chinese version of the EPDS was used to assess maternal psychological status at 6 weeks after delivery, and an EPDS score ≥10 points at 6 weeks after delivery was used as an indicator of PPD. The related factors affecting the occurrence of PPD were analyzed by one-way analysis, and the independent risk factors affecting the occurrence of PPD were analyzed by multifactorial logistic regression.
RESULTS: The incidence of PPD was approximately 5.0% (12/242) in the women who underwent vaginal delivery and received intrathecal labor analgesia and 11.1% (27/242) in those who underwent cesarean section. Multifactorial logistic regression analysis showed that advanced maternal age was a risk factor for PPD (odds ratio [OR], 1.31, 95% confidence interval [95% CI], 1.04-1.66; P=0.02); prenatal anxiety (OR: 8.48, 95% CI: 2.73-26.27; P=0.02) and depression (OR: 10.99, 95% CI: 2.18-55.37; P<0.001) were also risk factors for PPD. A second birth was a protective factor against PPD (OR: 0.09, 95% CI: 0.01-0.57, P<0.05).
CONCLUSION: Advanced maternal age and prenatal anxiety and depression were associated with the development of PPD in women who underwent vaginal delivery with intrathecal labor analgesia and those who underwent cesarean section. Obstetricians and gynecologists can identify mothers at high risk of PPD at an early stage and provide psychological counseling for mothers to reduce the incidence of PPD. However, studies with large sample sizes are still needed.
Experimental study on forming distribution of electrohydraulic forming with and without bridging wire
Authors: Jang Yoonho , Kim Minseok , Kim JEONG 
Published: October 2024

Abstract

Electrohydraulic forming (EHF) can solve shortcomings of deep drawing and electromagnetic forming by demonstrating a reduced bouncing effect, formation in narrow areas, and no effect on the electrical conductivity of the blank. Existing EHF conducts experiments by fastening wires that provide a forming force with variable position. Therefore, it is difficult to produce uniform spherical force, and the experiment is time-consuming and difficult to apply to industrial processes. In this study, wireless and wire-cross EHF are presented to reduce the time required for EHF experiments and produce a uniform forming force. The maximum forming height and forming distribution are evaluated using a 0.7 t SUS430 specimen and free bulge die. The experiment time required is measured by comparing new suggested EHF experimental method with conventional EHF. Wireless EHF is proposed to take the least time on experiment and produce a constant forming results. Wire-cross EHF is proposed to compensate for the amount of time it takes to connect fully connected wires in conventional EHF. However, it does not substantially reduce the experimental time. Wire-cross EHF has the advantage of higher energy efficiency than wireless EHF as it uses wires; however, it cannot completely overcome the fundamental problem of conventional EHF; resulting the various forming distribution for same experiment conditions and the significant time required for every experiment. In wireless EHF, two times of consecutive experiments are required to produce the similar height of conventional and Wire-cross EHF under an applied voltage of 6 kV. When conducting consecutive experiments, if the experiment is ready for the first time, only the capacitor must be repeatedly charged and discharged while maintaining a constant electrode spacing, making it possible to conduct the experiment faster and produce the consistent forming distribution for every experiment.
NEIL3 influences adult neurogenesis and behavioral pattern separation via WNT signaling
Authors: Berrocal Marion Silvana Fernández , Reis Amilcar , Rolseth Veslemøy , Suganthan Rajikala , Kuśnierczyk Anna , França Arthur , Soares Annara YM , Kunath Nicolas , Bugaj Anna M. , Abentung Andreas , Eide Lars , Leão Richardson N. , Bjørås Magnar , Scheffler Katja , Ye Jing 
Published: October 2024

Abstract

Adult neurogenesis in the hippocampus, involving the generation and integration of new neurons, is essential for behavioral pattern separation, which supports accurate memory recall and cognitive plasticity. Here, we explore the role of the DNA repair protein NEIL3 in adult hippocampal neurogenesis and behavioral pattern separation. NEIL3 is required for efficient proliferation and neuronal differentiation of neonatal NSPCs and adult-born NPCs in the hippocampus following a behavioral pattern separation task. NEIL3-depleted mice exhibited a reduced preference for the novel object location, indicating a deficit in pattern separation. NEIL3-deficient adult-born neurons exhibited a significant reduction in mature-like membrane properties, indicating impaired functional maturation. Interestingly, these impairments were not associated with the decreased genomic integrity but with the altered transcriptional regulation of the Wnt signaling pathway. Given the importance of adult neurogenesis in cognitive function, targeting NEIL3 could offer therapeutic potential for addressing age-related hippocampal dysfunction and cognitive decline.
Laparoscopic cholecystectomy in Dubin Jonson syndrome: Case Report
Authors: Wani Imtiaz 
Published: October 2024

Abstract

Introduction
Dubin-Johnson syndrome is an autosomal recessive disorder characterized by chronic conjugated hyperbilirubinemia. Black liver is seen peculiarly in this syndrome due to accumulation of a dark pigment in the liver parenchymal cells.
Case History
A young female having laparoscopic cholecystectomy had incidental diagnosis of Black liver during surgery. She had normal liver function tests.
Conclusion
Black liver may be detected as an incidental finding during Laparoscopic cholecystectomy for cholelithiasis.
Evolutionary relationships of Schistosoma japonicum
Authors: Nelwan Martin L. 
Published: October 2024

Abstract

Purpose: In this research, I investigated the phylogenetic relationships of Sschistosoma sinensium and Schistosoma japonicum, as well as the relationships between East Asia S. japonicum and Southeast Asia S. japonicum.
Results: The results of nucleotide BLAST showed that Sichuan S. sinensium AF465913.1 shares 72.29% identity with Jiangxi S. japonicum FJ852203.1. The E value is < 0.01. Schistosoma sinesium gave rise to S. japonicum in Jiangxi. Jiangxi S. japonicum spread to other parts of China, then to Japan, Southeast Asia, and Taiwan. It is close to, for example, S. japonicum from Anhui Tongling, Hunan Changde, and Indonesia. For example, the ND1 gene sequence of Jiangxi S. japonicum KP793763.1 shares 100% identity with that of Hunan Chande S. japonicum KP793756.1, 99.89% identity with Anhui Tonling S. japonicum KP793747.1 and Indonesia S. japonicum KP793779.1. E values = 0.0. Commonly, Indonesian S. japonicum, which includes S. japonicum from Anhui Guichi, Anhui Tongling, Hunan Changde, and Hunan Yueyang, is found in China. The genetic relationships of S. japonicum species are close to each others.
Conclusions: Schistosoma japonicum spread from Jiangxi to other parts of East Asia and Southeast Asia. The parasites have close genetic relationships.
Research Influence Heat Shock on the Quality of Post Goat Oocytes Warming Through Evaluation Maturation Rate and Inspection Protein Heat Shock (HSP-70), Adenosine Triphosphate (ATP), Glutathione (GSH)
Authors: Widjiati Widjiati , Darsini Ninik , Hendrawan Viski Fitri , Taqwa Sultan Fadhilla , Shabira Zahra 
Published: October 2024

Abstract

Local goat cultivation in Indonesia faces challenges due to imports of domestic goats, which threaten the genetic variation of local goats. To overcome this, veterinarians are directed to play a role in biotechnology, especially through the In Vitro Fertilization (IVF) method. This research is expected to show the identification of the three biomarkers, namely ATP, GSH, and HSP-70 from post maturation goat oocytes exposed to two different types of cryoprotectant, namely commercial cryoprotectant (Cryotech) and Ethylene glycol 30%+1M sucrose as well as comparing the quality of the goat oocytes after ELISA examination. This study used a completely randomized design with three groups of mature goat oocytes, consisting of one control group and two vitrification treatment groups with different cryoprotectants. Goat ovaries were collected from the Pegirian Surabaya slaughterhouse, then the oocytes were selected and matured in a CO2 incubator. The results showed that there was no significant difference in the maturation rate between the three groups of goat oocytes (control, Cryotech, and EG30%+1M Sucrose). However, there were significant differences in HSP70, GSH, and ATP levels. The EG30%+1M Sucrose group (Treatment 2) showed the lowest levels of HSP70 and GSH, but the highest levels of ATP compared to the other groups. This investigation demonstrates no significant difference in caprine oocyte maturation rates among the control and two cryoprotectant treatment groups. However, the EG30%+1M Sucrose treatment significantly altered HSP70, GSH, and ATP levels. Both cryoprotectants exhibited comparable efficacy in preserving oocyte quality during vitrification.