bluuebunny/crossref_metadata_2025_split huggingface dataset:
Human Umbilical Cord Mesenchymal Stem-Cell Therapy to Increase the Density of Osteoporotic Mandibular Bone
Authors: Hendrijantini Nike , Hartono Poedjo , Ari Muhammad Dimas Aditya , Rantan Fedik Abdul 
Published: June 2019

Abstract
Objective The aim of this study is to evaluate the feasibility of human umbilical cord mesenchymal stem-cell (hUCMSC) therapy in increasing osteoporotic mandibular bone density in a rat model by determining changes in alkaline phosphatase (ALP), osteocalcin, type 1 collagen, and trabecular bone area after treatment.
Materials and Methods This research adopted an experimental posttest-only control group design. Thirty female Wistar rats were randomly divided into six groups, namely, a control group with rats postsham surgery (T1), osteoporotic model postovariectomy rats (T2), postovariectomy rats 4 weeks after gelatin injection (T3), postovariectomy rats 8 weeks after gelatin injection (T4), postovariectomy rats 4 weeks after hUCMSC injection (T5), and postovariectomy rats 8 weeks after hUCMSC injection (T6). The rats were all sacrificed for histological and immunohistochemical examinations of ALP, osteocalcin, type 1 collagen, and trabecular bone area.
Results Increased expression of ALP, type 1 collagen, and osteocalcin, as well as increased trabecular bone area, was observed in the treatment groups compared with that in the osteoporotic groups.
Conclusion hUCMSCs produce significant osteogenic effects and increase osteoporotic mandibular bone density in the animal model. Increases in bone density are demonstrated by the higher levels of ALP, osteocalcin, and type 1 collagen, as well as increases in the trabecular bone area.
Effect of Different Neutralizing Agents on Feldspathic Porcelain Etched by Hydrofluoric Acid
Authors: Sriamporn Tool , Kraisintu Ploypim , See Lily Pachanin , Swasdison Somporn , Klaisiri Awiruth , Thamrongananskul Niyom 
Published: June 2019

Abstract
Objective The aim of this study was to evaluate the effect of neutralizing agents on the shear bond strength of hydrofluoric (HF)–etched porcelain in nonaging and aging conditions.
Subjects and Methods One hundred and twenty feldspathic porcelain specimens were prepared and divided into six groups to undergo different surface conditioning methods—group 1: control; group 2: HF; group 3: HF + calcium hydroxide; group 4: HF + calcium carbonate; group 5: HF + calcium gluconate; and group 6: HF + ultrasonic. All samples were immersed in 37°C distilled water for 24 h. Half of the samples were thermocycled in water for 5,000 cycles. The shear bond strength test was performed using a universal testing machine at a crosshead speed of 0.5 mm/min. Data were statistically analyzed by two-way ANOVA and Tukey's multiple comparison test at a 95% confidence level. The surface micromorphology and surface elements were analyzed using scanning electron microscope (SEM) and energy-dispersive X-ray spectroscopy (EDX), respectively.
Results The shear bond strengths of groups 2–6 were significantly higher than the control group in both aging and nonaging conditions (p < 0.05). There were no significant differences among all of the HF-etched porcelain groups (p > 0.05). SEM images of groups 2–6 illustrated similar patterns of irregularity on the specimen surfaces. Elemental analysis of EDX demonstrated identical elements on surfaces of specimens of groups 2–6.
Conclusion Within the limitations of this study, shear bond strength values between HF-etched porcelain, HF-etching followed by application of neutralizing agents, and HF-etching followed by ultrasonic cleaning were not significantly different in both nonaging and aging conditions.
Does Implant-Abutment Interface affect Marginal Bone Levels around Implants?
Authors: Elemek Eser , Urgancioglu Artun , Dincer Janberd , Cilingir Altug 
Published: June 2019

Abstract
Objective The use of dental implants with different types of surface roughness and implant-abutment interface has brought about a situation of marginal bone loss. Therefore, the aim of this study was to analyze and compare marginal bone levels of different types of osseointegrated dental implants with platform switch (Group A: Ankylos, Mannheim, Germany) and platform match (Group B: Dentsply Xive, Mannheim, Germany, and Group C: MIS Implant Technologies, Karmiel, Israel).
Materials and Methods One hundred and seven patients (52 men and 55 women) with a mean age of 54.79 (standard deviation ± 12.35) years and a total of 321 dental implants (Group A, n = 198; Group B, n = 58; and Group C, n = 65) placed in a private practice between April 2006 and May 2015 were retrospectively analyzed. In addition to demographic information and implant characteristics, marginal bone levels were evaluated by Image J (Wayne Rasband, National Institute of Health, Maryland) program.
Results The mean age of all patients was 54.79 ± 12.35 years, and 51.5% of them were women. Implants supporting fixed bridge were most commonly used in all groups (65%), whereas only 20% were restored with a single crown and 15% with overdentures. In total, 47.5% of all implants showed no marginal bone loss. Mean bone loss in Group A was significantly lower (0.81 ± 1.60 mm) as compared to Group B (1.58 ± 1.59 mm) and Group C (1.18 ± 1.36) (p < 0.005).
Conclusion Among different types of dental implants, platform switch seems to preserve marginal bone levels and increase the long-term success of dental implants.
In Vivo Measurement of Root Canal Wall Temperature at Different Stages Prior to Fiber Post Cementation
Authors: Caiado Ana Carolina Rocha Lima , Azevedo Cristiana Godoy Sartori , Giannini Marcelo , De Goes Mario Fernando , Rueggeberg Frederick Allen 
Published: June 2019

Abstract
Objective This study measured the in vivo temperature of prepared root canal walls during various stages of treatment prior to endodontic postcementation.
Materials and Methods One tooth each from five patients requiring endodontic treatment received conventional gutta-percha obturation. The coronal 4 mm of gutta-percha was removed by drilling and the canal wall temperature was measured. A sterile, saline rinse was applied, and another temperature value was recorded. Paper points were placed, and the wall temperature was recorded. A standardized period of 1.5 minute passed, simulating time needed to mix and place the resin cement and post (no resin was placed), after which the final wall temperature was obtained. The tooth was temporized and scheduled for prosthetic reconstruction. A one-way repeated measure analysis of variance (with Tukey's post hoc test) was performed among mean temperature values for each treatment stage (preset α 0.05).
Results Significant temperature differences were found among the treatment stages. Canal space drilling yielded the highest temperature (35.5 ± 0.8°C), while the lowest was obtained after saline rinsing (34.0 ± 0.9°C). The temperature of prepared root canal wall prior to postplacement (34.9 ± 1.2°C) and following paper point drying (34.8 ± 1.1°C) presented intermediate results, with no statistical difference between them.
Conclusions This study suggested that root canal wall temperature varied during various stages of preparation prior to endodontic post.
A Rare Case of Parietal Skull Fibrosarcoma: Reconstruction with Free Myocutaneous Flap and Infrared Thermography Monitoring
Authors: Romansky Roman , Naydenov Emanuil , Komitski Stefan 
Published: June 2019

AbstractFibrosarcoma of the skull is an extremely rare condition. We report a case of a male patient surgically treated by radical tumor excision and plastic reconstruction with a free myocutaneous latissimus dorsi flap. Revascularization on the side of the intervention was verified intraoperatively by using an infrared thermography camera in the follow-up period to evaluate flap vitality in addition to standard clinical monitoring. We observed no complications and achieved a good aesthetic result.
Root Anatomy and Canal Configuration of Maxillary Molars in a Brazilian Subpopulation: A 125-μm Cone-Beam Computed Tomographic Study
Authors: Mohara Nelson Tsutomu , Coelho Marcelo Santos , de Queiroz Nathalia Valle , Borreau Marcelle Louise Sposito , Nishioka Marko Massao , de Jesus Soares Adriana , Frozoni Marcos 
Published: June 2019

Abstract
Objective Knowledge of internal anatomy of the teeth is of great importance in endodontics, leading to success in root canal therapy (RCT). The aim of this study was to assess the root anatomy and canal configuration of maxillary molars in a Brazilian subpopulation using tomographic images using a voxel size of 125 μm.
Materials and Methods This in vivo retrospective study assessed 651 cone-beam computed tomographic scans from 328 maxillary first molars and 323 maxillary second molars. The images were assessed by two endodontists and an oral radiologist. Only permanent molars with fully developed roots and with no signs of RCT were included.
Results Maxillary first and second molars presented three separated roots in 99.39 and 90.09% of the cases, respectively. The presence of mesiolingual canals in the mesiobuccal roots was 64.22% for maxillary first molars and 33.56% for maxillary second molars. Distobuccal canals in the maxillary first and second molars presented Vertucci's Type I configuration in 99.39 and 99.66%, respectively, and palatal canals in the maxillary first and second molars presented Vertucci's Type I configuration in 99.69 and 99.68%, respectively. Maxillary second molars were more subjected to anatomical variations than first molars. Female patients presented higher prevalence of mesiolingual canals in the maxillary second molars.
Conclusions The most prevalent morphology in the maxillary first and second molars was three root canals. The presence of only one or two roots is more likely to occur in the maxillary second molars than in the maxillary first molars. Mesiolingual canals in mesiobuccal roots are more frequent in the maxillary first molars than in the maxillary second molars, and the occurrence of two distobuccal or two palatal canals is rare.
Ultraviolet A and Ultraviolet C Light-Induced Reduction of Surface Hydrocarbons on Titanium Implants
Authors: Naauman Zaheer , Rajion Zainul Ahmad Bin , Maliha Shahbaz , Hariy Pauzi , Muhammad Q. Saeed , Noor H. A. Razak 
Published: June 2019

Abstract
Objective The carbon, titanium, and oxygen levels on titanium implant surfaces with or without ultraviolet (UV) pretreatment were evaluated at different wavelengths through X-ray photoelectron spectroscopy (XPS).
Materials and Methods This interventional experimental study was conducted on nine Dio UFII implants with hybrid sandblasted and acid-etched (SLA) surface treatments, divided equally into three groups. Control group A samples were not given UV irradiation, while groups B and C samples were given UVA (382 nm, 25 mWcm2) and UVC (260 nm, 15 mWcm2) irradiation, respectively. The atomic ratio of carbon, titanium, and oxygen was compared through XPS.
Results Mean carbon-to-titanium ratio and C1 peaks considerably increased in Group A compared to those in experimental Groups B and C. The intensity of Ti2p and O1s peaks was more pronounced for group C compared to that for groups A and B.
Conclusions Although the decrease in surface hydrocarbons was the same in both UV-treated groups, the peak intensity of oxygen increased in the UVC-treated group. Thus, it can be concluded that compared with UVA irradiation, UVC irradiation has the potential to induce more hydrophilicity on SLA-coated implants.
Comparative Effect of Calcium Phosphate Biocomposite Materials on the Healing of Experimental Defect of Compact Bone Tissue
Authors: Korenkov Oleksii 
Published: June 2019

Introduction For the treatment of bone defects, a considerably large number of biocomposite calcium-phosphate materials has been developed and used. However, in the scientific literature, there is no information about the comparative effect of biocomposite materials based on β-tricalcium phosphate, hydroxyapatite, and collagen on the dynamics of healing of the defect of compact bone tissue.
Materials and Methods The experiment was performed on 48 white Wistar rats. In the middle third of the femoral shaft, a perforated defect 2.5 mm in diameter was reproduced in the bone marrow canal, which was filled with the calcium phosphate material Collapan (Intermedapatit, Moscow, Russia) (hydroxyapatite/collagen/antibiotics) in the animals of the first group, and with Guidor easy-graft Crystal (Sunstar S.A., Etoy, Switzerland) (hydroxyapatite/β-tricalcium phosphate) in the animals of the second group. Fragments of the injured bones were examined on the 15th and 30th days by light microscopy with morphometry and scanning electron microscopy.
Results It was found that, in the area of implantation of Collapan and of Guidor easy-graft Crystal, signs of inflammation were not detected, and osteogenic cells exhibited high topism to biocomposite materials. The biomaterials during the entire period of the experiment are subjected to resorption and replacement by the bone tissue of the regenerate. On the 15th and 30th days of the experiment, the predominance in the rate of biomaterial resorption (of 35.04% and 53.47%, respectively) and the formation of regenerate bone tissue (of 58.67% and 50.47%, respectively) was in the area of implantation of Collapan.
Conclusion The biocomposite materials tested exhibit a high biocompatibility, osteoconductive properties, and good integration with the tissues of the regenerate. However, the biocomposite material Collapan undergoes resorption and replacement by the bone tissue of the regenerate much faster, and Guidor easy-graft Crystal provides stability of the defect volume of compact bone tissue due to full resorption and good integration with the tissues of the regenerate.
Inpatient Cardiac Rehabilitation of LVAD Patients—Updated Recommendations from the Working Group of the German Society for Prevention and Rehabilitation of Cardiovascular Diseases
Authors: Reiss Nils , Schmidt Thomas , Langheim Eike , Bjarnason-Wehrens Birna , Marx Roger , Sindermann Jürgen R. , Knoglinger Ernst 
Published: June 2019

Cardiac rehabilitation physicians are faced to an increasing number of heart failure patients supported by left ventricular assist devices (LVAD). Many of these patients have complex medical issues and prolonged hospitalizations and therefore need special cardiac rehabilitation strategies including psychological, social, and educational support which are actually poorly implemented.Cardiac rehabilitation with clear guidance and more evidence should be considered as an essential component of the patient care plan especially regarding the increasing number of destination patients and their long-term follow-up.In this article the working group for postimplant treatment and rehabilitation of LVAD patients of the German Society for Prevention and Rehabilitation of Cardiovascular Diseases has summarized and updated the recommendations for the cardiac rehabilitation of LVAD patients considering the latest literature.
Ko-Konstruktion erkennen und verstehen – eine Analyse verschiedener Ko-Konstruktionstechniken in der Unterstützten Kommunikation
Authors: Renner Gregor , Hörmeyer Ina , Hoffer Lena 
Published: June 2019

ZusammenfassungDie gemeinsame Entwicklung einer Äußerung durch mindestens 2 Gesprächsteilnehmerinnen oder -teilnehmer – die sogenannte Ko-Konstruktion – ist für Menschen mit schwer verständlicher oder fehlender Lautsprache eine häufig verwendete Kommunikationsstrategie. Eine genaue Analyse zeigt, dass es verschiedene Arten der Ko-Konstruktion gibt, die sich in Form und Funktion unterscheiden. 2 häufig auftretende Muster sind die verständnissichernden Reparaturen sowie Hint und Guess-Sequenzen. Bei verständnissichernden Reparaturen zeigt die Gesprächspartnerin, dass zum Verständnis eine weitere Information notwendig ist, die von der unterstützt kommunizierenden Person gegeben wird. Bei einer Hint und Guess-Sequenz macht die Gesprächspartnerin auf der Grundlage der gegebenen unvollständigen Information und des eigenen Kontextwissens Vorschläge, die von der unterstützt kommunizierenden Person verworfen oder bestätigt werden.
Optimisation of CT thorax protocol for obese paediatric patients: A phantom study
Authors: Pham T N , Wong J H D , Chan W Y , Ng K H 
Published: June 2019

Abstract
The objective of this research was to obtain the optimal automatic exposure control (AEC) settings for CT thorax examinations for obese paediatric patients. This was to ensure lower radiation dose for this special cohort while maintaining diagnostic image quality. A layer of fat tissue equivalent material was used to wrap around the torso of a paediatric phantom to simulate an obese patient. Optically stimulated luminescence dosimeters (OSLDs) were inserted at different positions within the thorax region. Three sets of CT images were acquired at DoseRight Indices (DRI) of 13, 15 and 17. The CT images were used for qualitative and quantitative assessments. The contrast to noise ratio (CNR) of images with DRI of 13 (211.08 ± 21.35) were significantly lower than CNR of images with DRI of 15 (231.67 ± 20.35) and 17 (245.10 ± 25.44; p < 0.01). For signal to noise ratio (SNR), there were significant differences among images with all DRI settings (p < 0.01). The mean absorbed dose received by the phantom at DRI of 13, 15 and 17 were 1.07 ± 0.05 mSv, 1.16 ± 0.07 mSv and 1.75 ± 0.08 mSv, respectively. In this study, DRI of 15 was determined as the optimal setting for obese paediatric patients for the age group of 5 to 14 years old. We have demonstrated that there is scope to reduce radiation dose to obese paediatric patients in CT thorax examinations while still maintaining diagnostic quality images.
Two-dimensional electrical impedance tomography (EIT) for characterization of body tissue using a gauss-newton algorithm
Authors: Hikmah I , Rubiyanto A , Endarko  
Published: June 2019

Abstract
The gauss-newton algorithm is applied to reconstruct a two-dimensional image of Electrical Impedance Tomography (EIT) using python program. The study aimed to determine the characteristics of body tissues either conductive or resistive properties through the tissue structure which is displayed in the form of images so we can distinguish between one tissue and another. In this study, it was a fabricated hardware system, phantom, and software system. The EIT technique is performed by injecting a low constant electrical current of 1 mA at 50 kHz frequency on a pair of electrodes on 16 copper electrodes (Cu) surrounding a phantom filled with ground meat as conductor of electricity, flat bone, and cord bone of chicken as anomalies. The principle of the neighboring method achieved voltage measurements from the other electrode pair. The measurement data is processed with the python program using gauss-newton algorithm to obtain a reconstructed image of the tissue structure. The characteristics of body tissue can be identified from the color distribution, position, shape, and size of the object in the reconstructed image so it can distinguish between one tissue and another. The original analysis of body tissue either conductive or resistive properties could be reconstructed by two-dimensional electrical impedance tomography conjunction with the gauss-newton algorithm.
Axial absorbed dose distributions during abdominal computed tomography acquisitions: Measurement and the Monte Carlo simulation study
Authors: Matsubara K , Nagata H , Okubo R , Ogawa Y , Chusin T , Hirosawa A 
Published: June 2019

Abstract
We aimed to validate Monte Carlo (MC) simulation models against measurements and evaluate the effect of object size on axial absorbed dose distributions during abdominal computed tomography (CT) acquisitions based on MC simulations. A medium-sized abdominal phantom, with holes to insert a pencil ionization chamber, was acquired using a 192-slice dual-source CT scanner at a tube voltage of 120 kVp and a displayed volume CT dose index of 5.0 mGy. Absorbed doses were measured using the pencil ionization chamber and an electrometer, and normalized absorbed doses to center were calculated for all measurement locations. The Particle and Heavy Ion Transport code System version 3.02 was used to simulate normalized absorbed doses of 19 locations through small-, medium-, and large-sized abdominal phantom models with a tube voltage of 120 kVp. In the measurement and MC simulation, the normalized absorbed dose to center in the medium-sized abdominal phantom was 1.48 ± 0.28 and 1.62 ± 0.35, respectively. Higher normalized doses were observed at peripheral regions when the phantom size was larger.
Characterization of the changes in electroencephalogram power spectra due to sound stimulation
Authors: Khotimah S N , Suwandi G R F , Handayani N , Pratama S H , Putri S S M I , Haryanto F , Arif I 
Published: June 2019

Abstract
Music has an important role in our life nowadays. Music can affect emotions and brain activity that can be measured through brain waves as electrical signals produced by neurons to carry sensory and cognitive information. In this study, brain waves for 10-12 normal male-non musician undergraduate students under three kinds of treatment are read using wireless electroencephalography (EEG) with 14 channels. For the first treatment, EEGs data are recorded when the subjects are in relax condition, i.e. rest and listening music. For the second treatment, subjects were stimulated with music in two loudness levels and for the last treatment subjects were stimulated with two different tempos of a song. From all subjects of this work, it was obtained that the right brain hemisphere is more active when listening music (significance level of 0.02). The average power spectra slightly increase with increasing music loudness (significance level of 0.35-0.45). Changes in musical tempo cause a decrease of the power spectra of alpha and beta bands (significance level of 0.25-0.30).
Brain responses to frequency changes due to vibratory stimulation of human fingertips: An fMRI study
Authors: Seri FAS , Abd Hamid AI , Abdullah JM , Idris Z , Omar H 
Published: June 2019

Abstract
Vibratory (e.g., piezoelectric) devices can stimulate cortical responses from the somatosensory area during functional magnetic resonance imaging. Twelve healthy, right-handed subjects (7 males and 5 females) were scanned with a 3.0 T magnetic resonance imaging scanner and stimulated at 30-240 Hz using a piezoelectric vibrator attached to the subjects’ index fingers. The functional images were analysed to determine the brain activation region by performing random effects analyses at the group level. One-way analysis of variance was used to measure changes in frequency on brain activity. The activated regions were identified with WFU PickAtlas software, and the images were thresholded at Puncorrected < 0.001 for multiple comparisons. The average effect of frequency revealed significant activations in the right insula and right middle frontal gyrus; the corresponding region in the somatosensory area may act as a top-down control signal to improve sensory targets. Results revealed significant differences between frequencies; 90 Hz > 120 Hz activated right inferior parietal gyrus, 120 Hz > 150 Hz activated right cerebellum, and 60 Hz > 90 Hz activated right supramarginal gyrus and bilateral inferior frontal gyrus pars triangularis. Findings indicated the role of secondary somatosensory areas and the cerebellum in performing higher-order functions and discriminating various frequencies during vibratory stimulation. Increasing the patient sample size and testing higher frequencies in future experiments will contribute to furthering brain mapping of somatosensory areas.