bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rubber-based piezoresistive sensing: a new approach based on hydrodynamic flow of material deformation describing nonlinear signals in stretchable sensors
Authors: Harea Evghenii , Datta Sanjoy , Maloch Jaroslav , Stěnička Martin , Stoček Radek 
Published: November 2024

Abstract
The nonlinearity of piezoresistive response is critical in developing strain sensors, various self-monitoring applications and wearable electronics based on filled rubbers. This parameter could change dramatically when scaling up from small-size prototypes to full-scale production. The present work focuses on the nonlinear signals in stretchable rubber-based sensors, their origin and dependence on size of samples. Thus, a set of rectangular, piezoresistive samples differing in width was prepared from natural rubber reinforced with carbon black filler. Their electric resistance was tested under planar strain/recovery conditions at 25 and 50% strain amplitudes. It was found that piezoresistance and the related nonlinear phenomena significantly depended on the size of the samples. For the first time, hydrodynamic flow of deformed material was used to explain the nonlinearities of the piezoresistive signal. The trajectory, velocity, and magnitude of this flow were accounted for by a newly developed empirical equation describing the evolution of local resistivity under the strain/recovery process.
The role of femoral head size in metal-on-metal hip arthroplasty: analysis of a cohort of 3813 patients with long term follow-up
Authors: Ciatti Corrado , Andriollo Luca , Asti Chiara , Morsia Davide , Quattrini Fabrizio , Cosentino Monica , Bordini Barbara 
Published: November 2024

AbstractMetal-on-metal (MoM) large headed arthroplasties were suggested to decrease failure rates by means of reduced volumetric wear and enhanced implant stability. However, they caused high rates of revisions due to adverse reaction to metal debris, osteolysis, pseudotumor growth, and other issues. The study aims to present the long-term outcomes of MoM arthroplasties on a large cohort of patients, evaluating the impact of head sizes on survival rate. All data were retrieved from the regional joint register (Registro dell’Implantologia Protesica Ortopedica, RIPO, Italy). We include in the study all patient who underwent cementless MoM total hip arthroplasties (THAs) between 2000 and 2020, dividing them in two subgroups according to head size (<36 mm, ≥36 mm). Failures were recorded up to December 31, 2020. Patients lost to follow-up were excluded. A total of 3813 THAs met the inclusion/exclusion criteria. The average follow-up period is 12.4 years (0–21 years). 178/1625 (or 11.0%) small head MoM THAs and 265/2188 large head ones failed by the end of follow up. Large diameter heads reported lower survival rate (p-value < 0.001), with unexpected higher dislocation rate (1.0 vs. 0.4%). Moreover, large head size was found to increases the risk of metallosis (p-value < 0.0001). Gender, patient’s age and the use of modular neck were not correlated with higher failure rates. MoM implants implants do not have the same reliability as other couplings, considering the significantly greater failure/complication rates. However, the knowledge of risks linked to head size is fundamental for establishing the right type of follow-up to the patient and recognize any complications early.
The “full rectangle” sign: a novel method for ultrasonographic diagnosis of fetal aberrant right subclavian artery
Authors: Piura Ettie , Engel Offra , Doctory Neta , Markovitch Ofer 
Published: November 2024

Abstract
Objective
To evaluate the feasibility and accuracy of a novel ultrasonographic screening method for an aberrant right subclavian artery (ARSA) using the novel “full rectangle” method.

Methods
This prospective study was conducted at a tertiary care center, September 2022 to February 2023. The study included unselected pregnant women at 14–38 weeks of gestation referred for routine or targeted anomaly scans. All participants underwent scanning by two experienced sonographers to ascertain the presence or absence of aberrant right subclavian artery (ARSA) using both conventional and novel “full rectangle sign” methods for validation purposes. This is a novel screening method for ARSA that demonstrates the retro-tracheal course at the level of the supra-aortic vessels, forming what we term the “full rectangle sign”.

Results
A cohort of 138 patients was enrolled. The "full rectangle" sign was discerned in 6 fetuses with ARSA (4.3%), while the typical three-sided figure of the right subclavian artery was demonstrated in the remaining 132 fetuses (95.7%). The novel method demonstrated 100% feasibility and complete concordance with the conventional method.

Conclusion
The study results indicate that the full rectangle sign serves as an effective and dependable screening tool for identifying ARSA. It offers the advantage of a clear, unobstructed view at a level unaffected by sternum shadowing and eliminates confusion with the azygous vein.
Relationship between bone union and degree of bone marrow fibrosis at resection margins of advanced mandibular ORN
Authors: Ohori Hiroaki , Iwata Eiji , Ichikawa Chihiro , Shigeoka Manabu , Tadokoro Yoshiaki , Takeda Daisuke , Kusumoto Junya , Hasegawa Takumi , Akashi Masaya 
Published: November 2024

Abstract
Background
The pathological evaluation of cancellous bone at resection margins of mandibular osteoradionecrosis (ORN) has not been well elucidated. Here, we developed a unique classification system for evaluating the degree of bone marrow fibrosis, one of most common pathological features, in patients with mandibular ORN, based on which we investigated its relationship with treatment outcome.

Methods
This study included 15 patients who underwent mandibulectomy and free fibula osteocutaneous flap reconstruction. The extent of mandibulectomy was determined, with safety margins of approximately 10 mm from the apparent osteolytic areas on preoperative computed tomography image. Special staining was performed on thin sections from center of the osteolytic areas (medial area) and bilateral resection margins, and the degree of bone marrow fibrosis was evaluated and investigated its relationship with presence of bone union as a treatment outcome.

Results
The degree of bone marrow fibrosis of medial area was significantly higher than those of resection margins. Although most resection margins had collagen fibers which indicate severe fibrosis, all transferred fibula flaps achieved bone union.

Conclusion
When mandibulectomy is performed with safety margins of approximately 10 mm from the apparent osteolytic areas, all transferred fibula flaps achieved bone union regardless of the degree of bone marrow fibrosis at resection margin. In other words, the association between severe bone marrow fibrosis at resection margins and treatment outcome was not seen.

Clinical Relevance
Setting safety margins of approximately 10 mm may achieve bone union, but further study is needed.
Optimization of trigonometric polynomials with crystallographic symmetry and spectral bounds for set avoiding graphs
Authors: Hubert Evelyne , Metzlaff Tobias , Moustrou Philippe , Riener Cordian 
Published: November 2024

AbstractWe provide a new approach to the optimization of trigonometric polynomials with crystallographic symmetry. This approach widens the bridge between trigonometric and polynomial optimization. The trigonometric polynomials considered are supported on weight lattices associated to crystallographic root systems and are assumed invariant under the associated reflection group. On one hand the invariance allows us to rewrite the objective function in terms of generalized Chebyshev polynomials of the generalized cosines; On the other hand the generalized cosines parameterize a compact basic semi algebraic set, this latter being given by an explicit polynomial matrix inequality. The initial problem thus boils down to a polynomial optimization problem that is straightforwardly written in terms of generalized Chebyshev polynomials. The minimum is to be computed by a converging sequence of lower bounds as given by a hierarchy of relaxations based on the Hol–Scherer Positivstellensatz and indexed by the weighted degree associated to the root system. This new method for trigonometric optimization was motivated by its application to estimate the spectral bound on the chromatic number of set avoiding graphs. We examine cases of the literature where the avoided set affords crystallographic symmetry. In some cases we obtain new analytic proofs for sharp bounds on the chromatic number while in others we compute new lower bounds numerically.
Architectural views for social robots in public spaces: business, system, and security strategies
Authors: Oruma Samson , Colomo-Palacios Ricardo , Gkioulos Vasileios 
Published: November 2024

Abstract
This study delineates a suite of architectural views and a security perspective tailored to guide the deployment and integration of Social Robots in Public Spaces (SRPS). It commences with a business context view that utilizes the customer-producer-supplier model, underscoring the value of SRPS to various stakeholders and illustrating how robots can enhance user experiences and drive economic benefits. The system context view details the intricate interactions among the social robot, stakeholders, public spaces, and external systems, highlighting essential considerations for successful deployment, from technical configurations to stakeholder engagement. The functional view elaborates on the operational dynamics of the robot within its environment, focusing on user interaction and data management capabilities. Additionally, the security perspective delves into security considerations vital for safeguarding the SRPS across various domains, including identity and access management, application and network security, and data privacy. The paper also contextualizes these views through a city ferry use case, demonstrating their practical application and reinforcing the importance of multifaceted planning and analysis in real-world settings. This approach provides a strategic framework views for developing SRPS that are viable, efficient, and secure, fostering successful adoption in diverse public environments.
Diastereomers of the Anticancer Peptide CIGB-300 with Altered β-Turn Structures
Authors: Moya Celia G. , Rodriguez Rafael , Perez Carlos S. , Garay Hilda , Wiesent Julian , Gröger Stefan , Masforrol Yordanka , Perera Yasser , Perea Silvio E. , Balbach Jochen 
Published: November 2024

Abstract
Purpose
The next-generation anti-tumor drug peptide CIGB-300, developed by the Center for Genetic Engineering and Biotechnology (CIGB), targets casein kinase 2 (CK2) and its substrates, implicating significant therapeutic potential in cancer treatment. A key focus of this study was to compare CIGB-300 and a primary synthetic byproduct, CIGB-300iso, which shares the amino acid sequence with CIGB-300 but was proposed to differ due to racemization.

Methods
This study explores the synthesis, characterization, and structural elucidation of CIGB-300 and its isomer CIGB-300iso by a comprehensive NMR analysis of seven synthesized diastereomers including amino acid residues C15, H21, and C25.

Results
This study revealed that CIGB-300iso contains one D enantiomer at position H21. The structures of both isoforms derived from NMR constraints disclosed that the L and D enantiomers have an altered peptide supersecondary structure, with a β-turn type IV3 found in CIGB-300 and a type I β-turn in CIGB-300iso.

Conclusion
The configuration of H21 significantly impacts the peptide’s conformations, sidechain orientations and, potentially, its biological activity. These findings highlight the importance of enantiomerically pure peptides for the design and synthesis of drug peptides.
On the dynamics of transporting rolling cylinders
Authors: Honein Theresa E. , O’Reilly Oliver M. 
Published: November 2024

AbstractA common, yet hazardous, method of transporting cylindrical tanks used to carry compressed gas involves rolling both tanks at opposite angles of inclination to the vertical. By propelling one of the tanks while maintaining point contact between the tanks, both tanks can be moved such that their centers of mass move in a straight line. The purpose of this paper is to explore this locomotion mechanism. First, the problem of supporting an inclined cylinder in point contact with a rough surface is examined. The analysis shows that dependent on the geometry of the cylinder and the coefficient of static friction, a wide range of angles of inclination are feasible. The presence of non-integrable constraints on the motion of the rolling cylinder is explored using the concept of a holonomy. The problem of transporting two cylinders using the aforementioned mechanism is then analyzed with the help of Frobenius’ integrability criterion for constraints and numerical simulations. The results show the mechanical advantage of transporting a pair of cylinders, the range of possible angles of inclination, and the forces needed to sustain the motion.
Do Fans Make Poor Referees? Exploring Citizens’ Reactions to Partisan Gamesmanship
Authors: Claassen Ryan L. , Ensley Michael J. , Ryan John Barry 
Published: November 2024

AbstractPolitical (as opposed to professional) election oversight is one area in which the U.S. scores extremely low in measures of election integrity. Meanwhile, rancorous political battles to determine acceptable election procedures and judge when tactics cross the line have become common events. Our work contributes to recent scholarship investigating whether voters prioritize democratic principles or strategically favor electoral procedures that provide partisan advantage. In two survey experiments, we confirm that Americans’ attitudes about antidemocratic election tactics reveal more about which team they are cheering for than they do about whether the tactics are fraudulent. The tendency to engage in partisan motivated reasoning occurs among all partisans, but there are subtle differences as to when citizens will engage in it. Partisan motivated reasoning is more common when actions cause harm and by the partisans that are harmed. Finally, Independents are more impartial, but less likely to call out improper tactics in the aggregate because they often fail to condemn actions by either party.
The contribution of informal green space to urban biodiversity: a city-scale assessment using crowdsourced survey data
Authors: Stanford Hugh R. , Hurley Joe , Garrard Georgia E. , Kirk Holly 
Published: November 2024

Abstract
Cities are crucial for supporting biodiversity and are likely to play an important role in helping respond to the global biodiversity crisis. Understanding how plants and animals utilize various urban spaces is essential for designing cities that accommodate both human and ecological needs. Informal green spaces (IGS) have been historically overlooked in green space research and planning. However, there is growing interest in the potential benefit of IGS in supporting urban biodiversity. This study builds on previous research by examining the contribution of IGS to biodiversity at the metropolitan scale. We do this by mapping IGS across the entire urban landscape of Greater Melbourne, Australia, using crowdsourced ecological survey data to assess the role of IGS in supporting native bird and plant species richness. Our findings indicate that IGS contribute to urban species richness and can do so to a similar extent as formal green spaces. We found that utility easements and brownfield sites were particularly important types of IGS for supporting species richness. While formal green spaces like parks remain vital for urban biodiversity, IGS should be considered an integral part of urban greenspace networks. These findings underscore the need to more actively consider IGS in urban green space decision making in order to achieve positive urban biodiversity outcomes.
An Attempt to Predict Transparent Armor Ballistic Performance through Quasi-Static Punch Shear Test
Authors: Bautista Villamil A.A. , Maranon A. , Casas-Rodriguez J.P. , Benitez T. , Pavolini E. 
Published: November 2024

Abstract

Background
Transparent armor systems are traditionally designed following a trial-and-error approach, which involves high development costs associated with ballistic testing. This research article presents a novel methodology, termed quasi-static multi-punch shear testing, within the domain of transparent armor systems.

Objective
The primary aim is to establish a correlation between multi-hit ballistic tests at Level III-A according to the NIJ 0108.01 standard, achieved through an adaptation of the single-shot ballistic limit methodology, and the quasi-static multi-punch shear testing. The objective is to utilize a simple experimental methodology that provides insights into the multi-hit ballistic behavior of transparent armors.

Methods
Parameters such as absorbed energy and observed damage mechanisms were utilized to assess the potential relationship between these tests. Transparent armor samples that underwent testing using the quasi-static multi-punch shear test were subsequently cross-sectioned using a water jet cutting machine to facilitate visualization of material damage. In addition, drawing on insights from quasi-static multi-punch shear testing results, the K-means clustering algorithm was employed to predict the likelihood of a specific transparent armor system passing a multi-hit ballistic test.

Results
Various damage mechanisms were observed as a function of the punch displacement, and correlations were made with the load–displacement curves. Furthermore, the implementation of the K-means clustering algorithm successfully classified transparent armor into two groups: those that passed the ballistic test and those that did not.

Conclusions
This research significantly advances understanding of transparent armor system behavior under multi-hit conditions and offers a promising predictive tool for evaluating their performance through straightforward and cost-effective experimentation.
The COVID-19 legacy: consequences for the human DNA methylome and therapeutic perspectives
Authors: Gaetano Carlo , Atlante Sandra , Gottardi Zamperla Michela , Barbi Veronica , Gentilini Davide , Illi Barbara , Malavolta Marco , Martelli Fabio , Farsetti Antonella 
Published: November 2024

AbstractThe COVID-19 pandemic has left a lasting legacy on human health, extending beyond the acute phase of infection. This article explores the evidence suggesting that SARS-CoV-2 infection can induce persistent epigenetic modifications, particularly in DNA methylation patterns, with potential long-term consequences for individuals’ health and aging trajectories. The review discusses the potential of DNA methylation-based biomarkers, such as epigenetic clocks, to identify individuals at risk for accelerated aging and tailor personalized interventions. Integrating epigenetic clock analysis into clinical management could mark a new era of personalized treatment for COVID-19, possibly helping clinicians to understand patient susceptibility to severe outcomes and establish preventive strategies. Several valuable reviews address the role of epigenetics in infectious diseases, including the Sars-CoV-2 infection. However, this article provides an original overview of the current understanding of the epigenetic dimensions of COVID-19, offering insights into the long-term health implications of the pandemic. While acknowledging the limitations of current data, we emphasize the need for future research to unravel the precise mechanisms underlying COVID-19-induced epigenetic changes and to explore potential approaches to target these modifications.
Graphical Abstract: Impact of SARS-CoV-2 infection on the epigenetic landscape and individual response
Following SARS-CoV-2 infection, individuals may develop either a normal immune response or an aberrant one, such as a cytokine storm. Both scenarios can result in long-lasting consequences, known as “long COVID.” This condition can reshape the epigenetic landscape by altering DNA methylation patterns, contributing to the “epigenetic drift.” This drift, further influenced by various factors, can lead to changes in gene expression, immune functionality, and disease susceptibility. One significant consequence of the epigenetic drift is the acceleration of biological aging, which can profoundly impact personalized medical interventions. Created with BioRender.com.
Diminutivization and expressive lateralization in Tiania
Authors: Hyman Larry M. , Mbûûi Mwaambi G. 
Published: November 2024

AbstractIn this paper we provide a descriptive account of the interacting morphological, phonological, and lexical factors determining how diminutives are marked in Tiania [etianíá], an understudied variant of the Central Kenya Bantu language Kimeru. As in other languages, diminutivization in Tiania can indicate a decrease in size or quantity or express positive endearment or negative scorn, depending on the noun and the context. We will show that diminutivization is effected by transferring nouns into singular noun class 12 and plural class 13, as in other Bantu languages, but with two interesting variations: First, depending on the lexical class of the input noun, the diminutive prefixes will either replace or precede the noun’s prefix. In the latter case, the diminutive plural prefix may be added to either the singular or plural form of the base noun, again depending on the latter’s noun class. The second interesting variation is that the majority of nouns which have an /r/ in their stem or prefix replace such /r/’s by [l], something we refer to as “expressive lateralization”, e.g. e-rinyá ‘pit, cave (class 5)’ → ka-linyá ‘a small pit (class 12)’, ri-étwa˚ ‘name (class 5)’ → ka-li-étwa˚ ‘a sweet name’. To study the first variation, we systematically survey the diminutivization of nouns from all noun classes, singular and plural. To study the second variation, we track every one of 330 nouns with /r/ with respect to lateralization. In attempting to explain why such lateralization should occur, we consider augmentative and depreciative noun to noun derivations which also undergo /r/ → [l] as well as other derived word classes, e.g. adjectives, which sometimes undergo expressive lateralization, depending on whether they are denominal or deverbal (verbs never show such effects). Being that this is the only reported case we know of expressive lateralization, Tiania is both of typological interest as well as a mystery within Bantu and beyond.