bluuebunny/crossref_metadata_2025_split huggingface dataset:
Статистические подходы к анализу и моделированию сезонности в демографических данных
Authors: Родионова Лилия Анатольевна , Копнова Елена Дмитриевна 
Published: July 2019

Согласно майскому указу Президента (2018 г.), в число национальных целей и стратегических задач развития РФ на период до 2024 г. входят «обеспечение устойчивого естественного роста численности населения РФ и повышение ожидаемой продолжительности жизни до 78 лет». Возросшая необходимость мониторинга текущей демографической ситуации, изучение структуры демографических показателей, пристальное внимание научного сообщества к реализации национальных целей обусловили выбор темы настоящего исследования.
В работе исследовались проблемы моделирования сезонности демографических показателей РФ (числа рождений, числа умерших, младенческой смертности, числа заключенных браков) по ежемесячным данным Росстата за период 2007-2018 гг. Зарубежные исследования показали, что, наряду с традиционными демографическими методами, ARIMA-модели дают хорошие результаты при прогнозировании демографических показателей (численности населения, уровня рождаемости и смертности, продолжительности жизни населения). Использование статистического подхода на основе SARIMA-моделей в данной работе позволило получить адекватные модели с хорошими статистическими и прогностическими свойствами. Стационарность процессов с учетом сезонности анализировали на основе HEGY-теста. Исследуемые в работе показатели имели ряд особенностей, которые были учтены при моделировании. Ряды числа рождений и числа умерших имели второй и первый порядки интегрируемости соответственно и содержали детерминированную сезонность, ряд числа заключенных браков имел первый порядок обычной и сезонной интегрируемости, ряд младенческой смертности не содержал сезонность, что было подтверждено на основе анализа автокорреляционной функции и периодограммы. Для анализируемых показателей в работе были построены точечные и интервальные оценки прогноза на 2019 г. Для сравнения качества прогнозирования SARIMA-моделей в работе были оценены также сезонные модели Хольта-Уинтерса.
Уровень образования как фактор демографического прогноза
Authors: Щур Алексей Евгеньевич 
Published: July 2019

Книга посвящена вопросам прогнозирования численности и структуры населения Земли до конца XXI века. Рассматриваются как технические детали построения подобных демографических прогнозов, так и последствиям различных вариантов прогноза для будущих траекторий развития человечества. Особое внимание авторы уделяют уровню образования населения, важнейшей, по их мнению, составляющей человеческого капитала. При этом, как подчеркивается в книге, образовательная структура населения является не только производной от демографических изменений и скорости «экспансии образования» в различных регионах и странах мира, но и сама оказывает и будет оказывать существенное влияние на демографические процессы; именно в этом кроется ее определяющие значение для населения нашей планеты в XXI веке.
Endovascular treatment in the management of hemoptysis: Single Center Experience and Early Stage Clinical Results
Authors: OĞUZ Şükrü 
Published: July 2019

Background and objective: Endovascular treatment for bleeding control in the hemoptysis
was first performed and described in 1970’s. In the present day, bronchial
artery embolization is performed for all degrees of hemoptysis in benign and
malign pathologies. Case series to evaluate patients’ demographics, angiographic
findings, technical success of treatment, and early clinical success were
presented.Material-Methods: Between 2007-2018, the patients with hemoptysis
undergoing angiographic evaluation were included the study in Interventional
Radiology Unite. Patients’ demographics, angiographic findings, technical
success of treatment, and early clinical success were evaluated.Results: Thirty-seven patients who had angiographic pathologic
signs from 47 patients with hemoptysis were treated 91.8 % technical success
(n=34). Early stage clinical success, during the length of hospital stay or the
first month period, was achieved in 31 (91%) patients. The main angiographic
abnormality was parenchymal staining and the first choice agents were polyvinyl
alcohol (PVA) for embolization. There were no complications related to the
procedure. Conclusions: Results suggest that endovascular treatment in
patients with hemoptysis is a safe and an effective approach that supports
current literature.
Prevalence of external and internal lymphedema secondary to head and neck cancer treatment
Authors: Manhas Deep Jyoti , Saraf Aditya , . Arti 
Published: July 2019

<p class="abstract"><strong>Background:</strong> Patients of head and neck cancer are at risk of developing secondary lymphedema after being treated for head and cancer. The purpose of this study was to examine the prevalence of secondary head and neck (HNL) lymphedema in post treated patients of head and neck cancer (HNC).</p><p class="abstract"><strong>Methods:</strong> This was a prospective observational study including 48 head and neck cancer patients who were atleast 3 months post treatment. The present study was conducted in the department of ENT, GMC Jammu for a period of 1 year from February 2018 to March 2019.</p><p><strong>Results:</strong> Forty patients (43.34%) were males and 8 were females with age ranging from 25 to 82 years. 58.33% patients in our study had some form of lymphedema. Out of these patients, 21.43% had only external lymphedema, 35.71% had only internal lymphedema and 42.86% had combined lymphedema.</p><p><strong>Conclusions: </strong>Lymphedema should be examined in the patients with head and neck cancer patients.</p>
The Influence of Type of Solvent and Extraction Temperature of Corn Silk Extracts
Authors: Haslina - , Nazir Novizar , Wahjuningsih Sri Budi , Larasati Dewi 
Published: July 2019

Corn silk has not been well-utilized. Actually it has the capacity to develop into functional food because it contains bioactive compounds and high natural antioxidant such as flavonoids and phenolics and positive effects on human health. There are several factors that influence the quality of corn silks extracts, including ratio (raw:solvents) and extraction temperature. This research was couducted to determine the influence of ratio (raw:solvent) and extration temperature of corn silk extracts. The experimental design used Randomized Block Design (RBD) which consisted of two factors and 3 replications. The first factor was type of solvent. All treatment use (raw:solvents) ratio at (1:4). The first factor consists P1=raw:ethanol (1:4)(w/v), P2=raw:methanol (1:4)(w/v), P3=raw:ethyl acetate (1:4)(w/v), and P4=raw:acetone (1:4)(w/v). and the second factor was extraction temperature that consists S1=60°C, S2=70°C, and S3=80°C. Data were analyzed with analysis of variance, followed by Duncan Multiple Range Test (DMRT) test at 5% significant level. Parameters of chemical analysis were included (water, ash, protein, fat, and carbohyrate), and phytochemical analysis were included (total phenol, total flavonoid, activity antioxidant, beta carotene, and vitamin C). The results showed that the type of solvent and extraction temperature of corn silk extracts have significantly effect on water, ash, protein, fat, and, total phenol, total flavonoid, activity antioxidant, beta carotene, and vitamin C. Methanol solvent and extraction temperature at 60°C is the best treatment which have the highest protein and the lowest fat content at 18.22%±1.13 and 0.17%±0.02 respectively, and the highest total phenol, total flavonoid, activity antioxidant, beta carotene, and vitamin C at 8216.89±132.39 Î¼gGAE/g; 234.29±3.98 Î¼gGAE/g; 215.27ppm±3.87; 80.80%±1.84; and 8.84%±0.45 respectively.
Comorbid insomnia and arterial hypertension: pathogenetic models and promising biomarkers
Authors: Filchenko I. A. , Korostovtseva L. S. , Tereshchenko N. M. , Sviryaev Y. V. , Voznjouk I. A. 
Published: July 2019

The review describes the major mechanisms for the initiation and maintenance of comorbid insomnia and arterial hypertension based on the relevant pathogenetic scenarios of insomnia such as the concept of sympathetic activation, the neurobiological model of insomnia, and stress-diathesis model (or 3-P model). The clinical data are lacking, and available clinical studies indicate the association between blood pressure levels and the hyperactivation of the central nervous system during sleep, characterized by electroencephalographic β-activity, and with sleep latency. However, biologically active substances involved in “neurogenic inflammation” also play a significant role in homeostasis maintenance following the exposure to endogenous and exogenous stress factors. The functions of interleukin-6, gamma-aminobutyric acid, substance P, melatonin, serotonin and orexin in normal and pathological conditions indicate their contribution to the development of comorbid insomnia and hypertension. We emphasize the role of insomnia as a separate nosological unit, comorbid with hypertension, as well as the importance of research of molecular mechanisms underlying the association between insomnia and arterial hypertension aimed at identification of therapeutic targets and prognostic markers.
PENGARUH PERAN DEWAN PENGAWAS SYARIAH (DPS) DAN KOMITE AUDIT TERHADAP KEPATUHAN PADA PRINSIP SYARIAH
Authors: Hikmah Liatul , Oktaviana Ulfi Kartika 
Published: July 2019

<p><em>Sharia Supervisory Board (DPS) and Audit Committee are company organ for Responbility implementation of sharia Compliance in Sharia Community Financing Banks (BPRS). The purpose of this research was to test the role of Sharia Supervisory Board (DPS) and Audit Committee effects on compliance with sharia principles in Sharia Community Financing Bank (BPRS) in East Java.The research population was all BPRS of East Java Province which are registered in the Financial Service Authority (OJK) and Bank Indonesia (BI). The sample size was 15 institutions which were taken using purposive sampling method. Data collection method used approximation quantitative method with questionnaires with total 0f 38 questionnaires returned. This research used Data analysis multiple linear regression test with SPSS 16. The research variables include 19 indicators of DPS supervision activities, 7 indicators of Audit Committee responsibilities and 12 indicators of Shariah Compliance indicators.The results revealed that the role of Sharia Supervisory Board (DPS) partially had a negative effect. Its mean Shariah Complience in BPRS East Java has not been fully influenced role of DPS because DPS rarely visited to BPRS and certification levels are still low. While the role of the Audit Committee has a positive effect on Sharia compliance in the BPRS East Java. Simultaneously, the role of Sharia Supervisory Board (DPS) and Audit Committee had an effect on compliance with sharia principles in BPRS East Java. According to the dominant variables revealed that the role of Audit Committee is more influential on Compliance with Sharia Principles in BPRS East Java compared to the role of Sharia Supervisory Board (DPS ).</em></p><br /><p> </p>
HUBUNGAN PENGETAHUAN TENTANG GROWTH SPURT DENGAN SIKAP IBU MENYUSUI DALAM PEMBERIAN ASI PADA BAYI USIA 7-10 HARI
Authors: Faristasari Evvin , Wulandari Siswi , Amin Fita Avrista Vilusi 
Published: July 2019

<p><strong>Latar belakang: </strong>Banyak faktor yang berpengaruh dalam kegagalan ASI eksklusif. Misalnya istilah ASI tidak cukup, disini faktor ibu adalah peran utama dalam pemberian ASI kepada buah hatinya. Pada usia tertentu bayi mengalami percepatan pertumbuhan (<em>growth spurt</em>) atau disingkat GS. Bayi mengalami percepatan pertumbuhan pada usia 7-10 hari, 2-3 minggu, 4-6 minggu, 3 bulan, 6 bulan, 9 bulan atau lebih, atau bisa juga di waktu-waktu yang lainnya. Salah satu RSIA di Kota Malang ini memiliki kebijakan fasilitas rawat gabung antara ibu dan bayinya yang baru dilahirkan. Kebijakan ini secara langsung dapat mendukung proses pemberian ASI secara ekslusif. <strong>Metode Penelitian:</strong> penelitian ini merupakan analitik korelasional. Karakteristik responden dalam penelitian ini diklasifikasikan berdasarkan usia ibu, pendidikan ibu, dan paritas ibu. Terdapat 30 responden yang ikut serta dalam penelitian ini. <strong>Hasil:</strong> Hasil tabulasi silang dapat diketahui bahwa <em>p-value &lt; α</em><em> </em>(0,024 &lt; 0,05) dan simpulkan Ho ditolak dan H1 diterima yang menyatakan bahwa ada hubungan pengetahuan tentang <em>growth spurt </em>(percepatan pertumbuhan) dengan sikap ibu menyusui dalam pemberian asi pada bayi usia 7-10 hari dengan tingkat kepercayaan sebesar 95 %. <strong>Kesimpulan:</strong> tingkat pengetahuan ibu tentang growth spurt berhubungan dengan sikap ibu menyusui dalam pemberian asi pada bayi usia 7-10 hari.<strong></strong></p><strong>Kata Kunci</strong> : <em>growth spurt</em>, RSIA, ASI eksklusif, sikap ibu menyusui
Efecto de distribuciones a priori en los diseños D-óptimos Bayesianos para un modelo no lineal correlacionado
Authors: Mosquera Benítez Juan Carlos , López Rios Victor Ignacio 
Published: July 2019

En la práctica pueden surgir complicaciones a la hora de construir diseños óptimos para modelos de regresión no lineales, uno de los grandes problemas se evidencia cuando las observaciones son correlacionadas, debido a que éstas son tomadas de un mismo individuo, objeto o unidad experimental. Al momento de utilizar el criterio de D-optimalidad este depende tanto del vector de parámetros del modelo como de la estructura de correlación supuesta para el término de error. Una forma de evitar esta dependencia es mediante la inclusión de distribuciones a priori en el criterio de D-optimalidad. En este artículo se estudia el efecto que tiene la escogencia de diferentes distribuciones a priori, tales como las distribuciones Uniforme, Gamma y Log normal en la obtención de los diseños D-óptimos para un modelo no lineal, cuando los errores presentan diferentes estructuras de correlación. Se hallan los diseños al maximizar el criterio de D-optimalidad aproximado por el método de Monte Carlo. Además, se propone una metodología general que permite hallar diseños D-óptimos para cualquier tipo de modelo no lineal en presencia de observaciones correlacionadas. Finalmente, se propone comparar los diseños encontrados mediante el cálculo de las eficiencias tomando como diseño de referencia el obtenido con la distribución a priori Uniforme. Se aplica la metodología establecida en un caso de estudio, y se concluye que los diseños obtenidos dependen tanto de la estructura de correlacióncomo de la distribución a priori considerada.
Modeling Hydraulically Fractured Shale Wells Using the Fast-Marching Method With Local Grid Refinements and an Embedded Discrete Fracture Model
Authors: Xue Xu , Yang Changdong , Onishi Tsubasa , King Michael J. , Datta–Gupta Akhil 
Published: July 2019

Summary
Recently, fast–marching–method (FMM) –based flow simulation has shown great promise for rapid modeling of unconventional oil and gas reservoirs. Currently, the application of FMM–based simulation has been limited to using tartan grids to model the hydraulic fractures (HFs). The use of tartan grids adversely impacts the computational efficiency, particularly for field–scale applications with hundreds of HFs. Our purpose in this paper is to extend FMM–based simulation to incorporate local grid refinements (LGRs) and an embedded discrete fracture model (EDFM) to simulate HFs with natural fractures, and to validate the accuracy and efficiency of the methodologies.
The FMM–based simulation is extended to LGRs and EDFM. This requires novel gridding through the introduction of triangles (2D) and tetrahedrons (2.5D) to link the local and global domain and solution of the Eikonal equation in unstructured grids to compute the diffusive time of flight (DTOF). The FMM–based flow simulation reduces a 3D simulation to an equivalent 1D simulation using the DTOF as a spatial coordinate. The 1D simulation can be carried out using a standard finite–difference method, thus leading to orders of magnitude of savings in computation time compared with full 3D simulation for high–resolution models.
First, we validate the accuracy and computational efficiency of the FMM–based simulation with LGRs by comparing them with tartan grids. The results show good agreement and the FMM–based simulation with LGRs shows significant improvement in computational efficiency. Then, we apply the FMM–based simulation with LGRs to the case of a multistage–hydraulic–fractured horizontal well with multiphase flow, to demonstrate the practical feasibility of our proposed approach. After that, we investigate various discretization schemes for the transition between the local and global domain in the FMM–based flow simulation. The results are used to identify optimal gridding schemes to maintain accuracy while improving computational efficiency. Finally, we demonstrate the workflow of the FMM–based simulation with EDFM, including grid generation; comparison with FMM with unstructured grid; and validation of the results. The FMM with EDFM can simulate arbitrary fracture patterns without simplification and shows good accuracy and efficiency.
This is the first study to apply the FMM–based flow simulation with LGRs and EDFM. The three main contributions of the proposed methodology are (i) unique mesh–generation schemes to link fracture and matrix flow domains, (ii) DTOF calculations in locally refined grids, and (iii) sensitivity studies to identify optimal discretization schemes for the FMM–based simulation.
High fecal carriage of Extended Beta Lactamase producing Enterobacteriaceae among adult patients admitted in Referral Hospitals in Dar es salaam, Tanzania
Authors: Kibwana Upendo Ozeniel , Majigo Mtebe , Kamori Doreen , Manyahi Joel 
Published: July 2019

Abstract
Background
Multi-drug resistance pathogens such as Extended-Spectrum Beta-Lactamase (ESBL) producing Enterobacteriaceae (ESBL-PE) are of great global health concern, since they are associated with increased morbidity and mortality. Even in the absence of infections caused by these pathogens, colonization is a great threat and can lead to cross transfer among hospitalized patients. To date data on carriage of these pathogens is still limited in Tanzania. Therefore, this study aimed to determine ESBL-PE fecal carriage rate and associated factors among hospitalized patients at Referral hospitals in Dar es Salaam.
Methods
This was a cross sectional study conducted from May to July 2017 among patients admitted in three referral hospitals in Dar es Salaam, Tanzania. Rectal swabs were collected and screened for ESBL production using MacConkey agar supplemented with Ceftazidime 1mg/L. Phenotypic confirmation of ESBL-PE was done by double disk diffusion method. Statistical analysis was performed using Statistical Package for Social Sciences (SPPS) software version 20.
Results
Of the 196 enrolled participants, 59.7% (117/196) were confirmed to carry ESBL-PE. A total of 131 ESBL-PE were isolated from 117 patients, whereby, Escherichia coli accounted for 68.7%, Klebsiella pneumoniae 28.2% and Citrobacter species 0.8%. ESBL-PE carriage was significantly higher in patients with diarrhea compared to those without diarrhea (72% vs 53.1%, p=0.01). Recent antibiotic use was independently associated with carriage of ESBL-PE (aOR 14.65, 95%CI 3.07-69.88, p=0.01).
Conclusions
High fecal carriage of ESBL-PE was observed in patients admitted in tertiary hospitals in Dar es Salaam, Tanzania. The use of antibiotics was associated with carriage of ESBL producers among the study population.
Multidrug-resistant tuberculosis in Ho Chi Minh City: a retrospective study of 2,267 cases from 2011 to 2015
Authors: Van Le Hong , Phu Phan Trieu , Vinh Dao Nguyen , Son Vo Thanh , Hanh Nguyen Thi , Nhat Le Thanh Hoang , Lan Nguyen Huu , Vinh Truong Van , Trang Nguyen Thi Mai , Ha Dang Thi Minh , Thwaites Guy , Thuong Nguyen Thuy Thuong 
Published: July 2019

Abstract
Background

Multidrug resistant tuberculosis (MDR-TB) remains a serious public health problem with poor treatment outcome. Predictors of poor outcomes vary in different health-care settings. Vietnam is among the 30 countries with high burden of MDR-TB. We aim to describe demographic characteristics and identify risk factors for poor outcome of MDR-TB in Ho Chi Minh City (HCMC), the most populous city in Vietnam.

Methods

This retrospective study included 2,267 patients who initiated MDR-TB treatment from 2011 to 2015 in HCMC. Treatment outcomes were available in 2,241 patients. Data was collected from standardized paper-based treatment cards and electronic records. Statistical analysis was performed using R program.

Results

Among 2,267 eligible cases, 60.2% were failure of category I or II regimen, 57.7% were underweight, 30.2% had diabetes mellitus and 9.6% were HIV positive. Notification rate increased 24.7% from 2011 to 2015.Treatment success rate was 73.3%. Risk factors for poor treatment outcome included HIV co-infection (odds ratio (OR): 2.92), advanced age (OR: 1.47 for every increase of 5 years for patients older than 60), having history of MDR-TB treatment (OR: 5.65), sputum smear grade scanty and 1+ (OR: 1.48), smear grade 2+ or 3+ (OR: 2.07), low BMI (OR: 0.84 for every increase of 1kg/m2 of BMI for patients with BMI<21).

Conclusion

Our study describes the increasing burden of MDR-TB in HCMC and the need for better drug resistance screening for all TB patients. Patients with HIV, high smear grade, malnutrition and history of previous MDR-TB treatment should receive additional care.
Spatial Distribution of Ascariasis, Trichuriasis and Hookworm Infections in Ogun State, Southwestern Nigeria
Authors: Mogaji Hammed , Dedeke Gabriel Adewunmi , Bada Babatunde Saheed , Bankole Samuel O. , Adeniji Adejuwon , Fagbenro Mariam Tobi , Omitola Olaitan Olamide , Oluwole Akinola Stephen , Odoemene Nnayere Simon , Ekpo Uwem Friday 
Published: July 2019

Abstract
Background

Ascariasis, Trichuriasis and Hookworm infections poses a considerable public health burden in Sub-Saharan Africa, and a sound understanding of their spatial distribution facilitates to better target control interventions. This study, therefore, assessed the prevalence of the trio, and mapped their spatial distribution in the 20 administrative regions of Ogun State, Nigeria.
Methods

Parasitological surveys were carried out in 1,499 households across 33 spatially selected communities. Fresh stool samples were collected from 1,027 consenting participants and processed using ether concentration method. Households were georeferenced using a GPS device while demographic data were obtained using a standardized form. Data were analysed using SPSS software and visualizations and plotting maps were made in ArcGIS software.

Results

Findings showed that 19 of the 20 regions were endemic for one or more kind of the three infections, with an aggregated prevalence of 17.2%. Ascariasis was the most spatially distributed found in 28 communities, with 140(13.6%) infected subjects, followed by Hookworm infection in 19 communities, with 47(4.6%) infected subjects and Trichuriasis in 9 communities, with 17(1.7%) infected subjects. The spatial distribution of infections ranges between 5.3 – 49.2% across the regions. The highest and lowest distribution was recorded in Yewa South and Yewa North respectively. By WHO preventive chemotherapy thresholds, 9 regions had infection status between 20.0%-49.2%, while 10 regions had infection status between 5.3%-15.8%.

Conclusion

This study provides information on the prevalence and spatial risk of Ascariasis, Trichuriasis and Hookworm infection that will serve as decision-support tool to help facilitate targeting of control interventions.