bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of Repeated Group Measurements with Drop Out Animals for Variance Component Estimation and Genetic Evaluation: A Simulation Study
Authors: Gao Hongding , Nielsen Bjarne , Su Guosheng , Madsen Per , Jensen Just , Christensen Ole F , Ostersen Tage , Shirali Mahmoud 
Published: July 2019

Abstract
The efficiency of feed utilization plays an important role in animal breeding. However, measuring feed intake (FI) is costly on an individual basis under practical conditions. Using group measurements to model FI could be practically feasible and cost-effective. The objectives of this study were to develop a random regression model based on repeated group measurements with consideration of missing phenotypes caused by drop out animals. Focus is on variance components (VC) estimation and genetic evaluation, and to investigate the effect of group composition on VC estimation and genetic evaluation using simulated datasets. Data were simulated based on individual FI in a pig population. Each individual had measurement on FI at 6 different time points, reflecting 6 different weeks during the test period. The simulated phenotypes consisted of additive genetic, permanent environment, and random residual effects. Additive genetic and permanent environmental effects were both simulated and modeled by first order Legendre polynomials. Three grouping scenarios based on genetic relationships among the group members were investigated: (1) medium within and across pen genetic relationship; (2) high within group relationship; (3) low within group relationship. To investigate the effect of the drop out animals during test period, a proportion (15%) of animals with individual phenotypes was set as the drop out animals, and two drop out scenarios within each grouping scenario were assessed: (1) animals were randomly dropped out; (2) animals with lower phenotypes were dropped out based on the ranking at each time point. The results show that using group measurements yielded similar VCs estimates but with larger SDs compared with the corresponding scenario of using individual measurements. Compared to scenarios without drop out, similar VC estimates were observed when animals were dropped out randomly, whereas reduced VC estimates were observed when animals were dropped out by the ranking of phenotypes. Different grouping scenarios produced similar VC estimates. Compared to scenarios without drop out, there were no loss of accuracies of genetic evaluation for drop out scenarios. However, dropping out animals by the ranking of phenotypes produced larger bias of estimated breeding values compared to the scenario without dropped out animals and scenario of dropping out animals by random. In conclusion, with an optimized group structure, the developed model can properly handle group measurements with drop out animals, and can achieve comparable accuracy of genetic evaluation for traits measured at the group level.
Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5
Authors: Folco H Diego , McCue Andrea , Balachandran Vanivilasini , Grewal Shiv I S 
Published: July 2019

AbstractHeterochromatin enriched in histone H3 lysine 9 methylation (H3K9me) and HP1 proteins coats chromosomal domains throughout the eukaryotic genome to regulate gene expression and maintain genome stability. How heterochromatin assembly mechanisms are...The fission yeast Schizosaccharomyces pombe is a powerful genetic model system for uncovering fundamental principles of heterochromatin assembly and epigenetic inheritance of chromatin states. Heterochromatin defined by histone H3 lysine 9 methylation and HP1 proteins coats large chromosomal domains at centromeres, telomeres, and the mating-type (mat) locus. Although genetic and biochemical studies have provided valuable insights into heterochromatin assembly, many key mechanistic details remain unclear. Here, we use a sensitized reporter system at the mat locus to screen for factors affecting heterochromatic silencing. In addition to known components of heterochromatin assembly pathways, our screen identified eight new factors including the cohesin-associated protein Pds5. We find that Pds5 enriched throughout heterochromatin domains is required for proper maintenance of heterochromatin. This function of Pds5 requires its associated Eso1 acetyltransferase, which is implicated in the acetylation of cohesin. Indeed, introducing an acetylation-mimicking mutation in a cohesin subunit suppresses defects in heterochromatin assembly in pds5∆ and eso1∆ cells. Our results show that in cells lacking Pds5, cohesin interferes with heterochromatin assembly. Supporting this, eliminating cohesin from the mat locus in the pds5∆ mutant restores both heterochromatin assembly and gene silencing. These analyses highlight an unexpected requirement for Pds5 in ensuring proper coordination between cohesin and heterochromatin factors to effectively maintain gene silencing.
Prevention and treatment of brain damage in streptozotocin induced diabetic rats with Metformin, Nigella sativa, Zingiber officinale, and Punica granatum
Authors: Sangi Sibghatullah Muhammad Ali , Jalaud Nora Abdulaziz Al 
Published: July 2019

Introduction: Diabetes mellitus (DM) is well-known metabolic disorder, which causes serious effects on human health with its complications. Many mechanisms has been postulated to cause DM related complications. One of the main complications is neuronal damage, for which no proper preventive and curative therapies are available.
Methods: In this study the effects of Ginger, Nigella sativa, Punica granatum and Metformin were seen on the prevention and treatment of brain damage caused by diabetes mellitus in streptozotocin (STZ)- induced diabetes in rats. 50 adult Wistar albino male rats were used in the study, the rats were divided in 10 study groups. The body weight, serum glucose levels were measured, and histopathological examination was performed.
Results: In comparison to the diabetic control rats, significant increase in weight was found in animals of all the studied groups. Serum glucose levels reduced significantly in comparison to the STZ induced diabetic rats in all the animals. Histopathological examination showed prevention from brain damage and repair of the neuronal tissues by Ginger, Nigella sativa, Punica granatum and Metformin.
Conclusion: The studied substances were observed to possess preventive and curative effects on the brain damage caused by diabetes mellitus.
Sifat Antibakteri dari Daun Tephrosia vogelii Terhadap Vibriosis
Authors: Bachtiar Eri , Syah Yana Maolana , Juliawaty Lia Dewi 
Published: July 2019

Sektor kelautan dan perikanan merupakan salah satu sumber andalan dalam produksi pembangunan perikanan di Indonesia. Udang merupakan salah satu komoditas unggulan utama dalam menunjang produksi pendapatan devisa non migas. Untuk mencapai target produksi sesuai dengan yang diharapkan, berbagai permasalahan menghambat upaya peningkatan produksi tersebut, antara lain kegagalan produksi akibat penyakit oleh bakteri Vibrio, sehingga penyakit ini dikenal sebagai ‘vibriosis’. Salah satu pencarian senyawa yang bersifat antibakteri adalah dengan cara melakukan penapisan terhadap senyawa-senyawa alam. Salah satu sumber senyawa alam adalah dari tumbuhan Tephrosia vogelii. Penelitian ini bertujuan untuk mengidentifikasi dan mengisolasi senyawa dari tumbuhan T. vogelii sebagai sumber senyawa antibakteri terhadap dua bakteri Vibrio yaitu Vibrio alginolitycus dan Vibrio harveyi. Bahan ekstrak dibuat dengan metode maserasi menggunakan pelarut aseton, sementara uji antibakteri dilakukan dengan metode difusi agar secara in vitro. Deguelin dan tefrosin kemudian diisolasi dari ekstrak aseton daun T. vogelii. dengan metode difusi agar senyawa deguelin memberikan nilai inhibisi 6,3 mm terhadap V. harveyi dan 6,2 mm terhadap V alginolitycus. Sedangkan tefrosin memberikan nilai inhibisi 6,3 mm terhadap V. harveyi dan 6,6 mm terhadap V alginolitycus. Ini adalah evaluasi antibakteri pertama dari deguelin dan tefrosin terhadap dua bakteri yang diuji.
Studi Keadaan Oksidasi Besi pada Air Hujan
Authors: Hidayah Hidayah , Suhendar Dede , Sudiarti Tety , Maesaroh Emay 
Published: July 2019

Air hujan merupakan sumber air permukaan dan air tanah. Air hujan terbentuk melalui beberapa proses yakni kondensasi, presipitasi, evaporasi, dan transpirasi. Air hujan memiliki kandungan besi dalam bentuk partikulat dan terlarutnya seperti ferro (Fe2+) dan ferri (Fe3+). Tujuan dari penelitian ini yaitu untuk menentukan kandungan Fe total, Fe(II) dan Fe(III) dalam air hujan serta perbandingannya dengan air hujan dari tiga tempat yang berbeda dan untuk mempelajari kandungan air hujan yang dapat mereduksi Fe(III). Fe total dianalisis dengan menggunakan instrumen Spektrofotometer Serapan Atom (SSA). Ion Fe(II) dan Fe(III) dianalisis dengan instrumen Spektrofotometer UV-Vis menggunakan ligan Fenantrolin dan KSCN sehingga membentuk senyawa kompleks [Fe(C12H8N2)3]2+ dan [Fe(SCN)6]3-. Derajat keasaman air hujan dianalisis menggunakan pH meter sedangkan keadaan oksidasi besi pada air hujan dianalisis menggunakan Spektrofotometer UV-Vis dengan pelarutan aqua dm dan air hujan yang turun di kawasan industri, pegunungan dan pemukiman. Hasil analisis menunjukkan kandungan Fe total, Fe(II) serta Fe(III) dalam air hujan yang turun sekitar industri, pegunungan dan pemukiman secara berturut-turut yaitu Fe total 0,5655; 1,6854; dan 2,4232 ppm, Fe(II) 0,0867; 0,2232 dan 0,0731 ppm, dan Fe(III) 0,5198; 0,4994 dan 0,5672 ppm. Dari perbandingan geseran panjang gelombang maksimum sinar tampak larutan FeSO4.7H2O teknis dan pro analisis dengan pengompleks fenantrolin diperoleh bahwa air hujan memiliki daya reduksi terhadap ion Fe3+.
Briket Arang Tempurung Kawista (Limonia acidissima) Teraktivasi NaOH dengan Perekat Alami
Authors: Yulianti Eny , Jannah Raudatul , Khoiroh Lilik Miftahul , Istighfarini Vina Nurul 
Published: July 2019

Penelitian tentang pemanfaatan tempurung tempurung kawista (Limonia acidissima) telah dilakukan sebagai bahan dasar pembuatan briket arang. Variabel jenis perekat alami berupa gel yang terbuat dari tepung beras, tepung ketan, dan tepung tapioka. Selanjutnya jenis perekat alami terbaik ditentukan, yang mampu menghasilkan nilai kalor tertinggi dan kualitas briket tempurung kawista sesuai dengan SNI. Metode perlakuan terhadap tempurung kawista meliputi aktivasi NaOH 0,1 M, karbonisasi, pencetakan dan pengepresan. Karakterisasi briket arang dilakukan melalui uji mutu SNI, termasuk penentuan nilai kalor tertinggi, serta identifikasi gugus fungsi sampel kulit, arang kulit, dan briket arang menggunakan spektrofotometer FTIR. Hasil penelitian menunjukkan bahwa perlakuan aktivasi meningkatkan kualitas briket arang. Penggunaan semua jenis perekat dengan perbandingan massa arang : perekat sebesar 9 : 1, menghasilkan briket arang yang memenuhi kualitas SNI. Nilai kalor tertinggi sebesar 6905 kal/g terdapat pada sampel briket arang tempurung kawista teraktivasi dengan jenis perekat alami gel tepung beras. Melalui penentuan mutu briket arang terbaik sesuai standar SNI, diperoleh nilai kadar air 3,733%, kadar zat menguap 8,014%, kadar abu 2,373%, dan kadar C terikat 85,88%. Secara garis besar, keseluruhan gugus fungsi yang teridentifikasi hampir sama yaitu meliputi gugus O–H pada 3500-3400 cm-1, C=C pada 1650-1600 cm-1, C–H pada 1384-1383 cm-1, dan C–OH pada daerah 1047-1034 cm-1. Perbedaan yang nampak adalah briket arang yang teraktivasi memiliki intensitas yang lebih tinggi dibandingkan dengan briket tanpa aktivasi
Ideologi Surat Kabar dalam Pemberitaan Terorisme
Authors: Syuderajat Fajar 
Published: July 2019

This paper this study was to determine the ideology of Newspaper Coverage Off Execution Amrozy Cs. on Newspaper Kompas and Republika. The method used in this research is the analysis method semiotics model of Ferdinand de Saussure with a qualitative approach. The results showed that: (a) Option speech text, as well as the news angle images of photographs or illustrations that reproduce the graph becomes a news event is strongly influenced by the ideology of the media is concerned. (B) Compass showing partiality to the international agenda by using the term "terrorists" in its message. This is also strengthened by the news in the form of photo illustrations which only includes figures or portraits of security officers. (C) Republika has a distinctive news angle in reporting the death penalty convicted Bali Bombing Case. They appear at the peculiarities of the text selection, angle coverage, as well as news illustrations are photographs which contains many figures or portraits Amrozi.
Kontruksi Realitas Motif Polisi Lalu-Lintas Kota Bandung
Authors: Nugraha Asep Dion 
Published: July 2019

The policeman performance frequently gets public criticism, but many people are interested in applying job as a police officer. There are particular motives in each person which leads him to choose a profession as a policeman. Because of the reasons and drive in human, the ones do something. This research uses a qualitative approach, that is, Constructing Reality of Bandung Traffic Policeman, by using a phenomenology study analysis. The results of the research are: expectancy and past experience motives; economic need motives; gallant motives, commanding and prestigious; family and environment motives; destiny, fortune, or fate motives; with typication: self-esteem fulfillment; interaction and self-actualization; achievement fulfillment; finally he becomes a wise or sensible (‘arif) person.
Strategi Komunikasi Pengelolaan Zakat, Infak, dan Sedekah (ZIS) Melalui Media Sosial
Authors: Herman Herman 
Published: July 2019

Tujuan penelitian ini untuk mengetahui bagaimana Strategi komunikasi pengelolaan Zakat, Infak, dan Sedekah (ZIS) melalui media sosial di Lembaga Amil Zakat Nasional Daarut Tauhiid Peduli (LAZNAS DT Peduli). Metode penelitian yang digunakan adalah metode deskriptif dengan jenis pendekatan kualitatif. Setelah melakukan penelitian, dapat disimpulkan bahwa strategi komunikasi pengelolaan Zakat, Infak, dan Sedekah (ZIS) melalui media sosial di Lembaga Amil Zakat Nasional Daarut Tauhiid Peduli cukup berhasil. Hal ini nampak pada grafik yang terus meningakat sampai dengan akhir September 2017, bahwa dana donasi online ke DT Peduli terhimpun sebesar Rp. 8,44 Milyar. The purpose of this study was to determine (1) the strategy of managing Zakat, Infaq, and Alms (ZIS) through social media at the Daarut Tauhiid Peduli National Zakat Institution (LAZNAS DT Peduli) (2) Communication on Zakat, Infaq, and Alms (ZIS) Management in Daarut Tauhiid Peduli National Institute of Zakat (LAZNAS DT Peduli) (3) Results of the management of Zakat, Infaq, and Alms (ZIS) through social media at the Daarut Tauhiid Peduli National Zakat Institute (LAZNAS DT Peduli). The research method used is descriptive method with a type of qualitative approach. After conducting research, it can be concluded that the communication strategy for the management of Zakat, Infaq, and Alms (ZIS) through social media at the Daarut Tauhiid Peduli National Zakat Institution is quite successful. This is evident on the graph that continues to increase until the end of September 2017, that the online donation fund to DT Peduli is collected in the amount of Rp. 8.44 Billion.
Efektivitas Komunikasi Dakwah Di Pesantren MQ dalam Merubah Akhlak Santri
Authors: Sudiansyah Agus 
Published: July 2019

Indonesia has different types of educational institutions including a state owned institution and a private one. However, recently, several types of educational institutions in Indonesia have some attention from the society in terms of the development of behavioral character of the youth that tend to be degrading. Effective communication of dakwah(preaching) at Pesantren MQ Tebuireng (MQ Tebuireng Islamic Boarding School) as well as akhlak(behavior) education is believed to be able to improve the behavior or so called akhlak of the Indonesian youth to be better. It can be seen from this study, a study at Pesantren MQ Tebuireng aimed at finding the influence and correlation between the effectivity of communication of dakwah and akhlak education towards students. This study is a Quantitative study. The data in this study are obtained through survey using a proportional stratification sample tehnique towards 172 students at Pesantren MQ Tebuireng. The study shows that there is a simultaneous influence between an effective communication of dakwah and akhlak education towards students where Fcount of 18.009 > Ftable of 3.05. However, there is also a correlation with r value of .749. According to Priyato, the r value of .60 - .799 shows a strong correlation, i.e. between the effectivity of communication of dakwah and akhlak education towards students. Indonesia memilki bebearapa lembaga pendidikan, yakni lembaga pendidikan milik pemerintah dan lembaga milik per orangan, sedangkan sekarang beberapa lembaga pendidikan di Indonesia mendapat sorotan dari masyarakat mengenai pengembangan karakter tingkah laku generasinya yang mulai menurun. Komunikasi dakwah yang efektif di Pesantren MQ Tebuireung dan pembinaan akhlak diyakini dapat meningkatkan tingkah laku atau akhlak generasi di Indonesia menjadi lebih baik. Terbukti hasil penelitian di Pesantren MQ Tebuireung dengan tujuan ingin mengetahui pengaruh dan hubungan efektivitas komunikasi dakwah dan pembinaan akhlak terhadap akhlak santri. Penelitian ini merupakan penelitian Kuantitatif. Data dikumpulkan melaui survei dengan teknik sampel stratifikasi proporsional terhadap santri di Pesantren MQ Tebuirung berjumlah 172 santri. Hasil penelitian menunjukan terdapat pengaruh secara simultan dengan F Hitung 18,009> F Tabel 3,05, komunikasi dakwah yang efektif dan pembinaan akhlak terhadap akhlak santri, dan terdapat hubungan atau korelasi dengan r sederhana dengan nilai 0,749, menurut Priyato nilai 0,60-0,799 sangat kuat hubungannya dari efektivitas komunikasi dakwah dan pembinaan akhlak terhadap akhlak santri.
Pola Komunikasi Perempuan Pesisir: Studi Etnografi Komunikasi
Authors: Nurhidayah Yayah 
Published: July 2019

Communication is bound by culture. As culture differs from one another, the communication practices and behaviors of individuals cared for in different cultures will have different communication methods. The coastal women's community is a sub-culture of the Cirebon community, besides having unique and distinctive characteristics, they have an important role in helping to increase the economic income of the fishermen's family. The involvement of coastal women in the public sphere is increasingly expanding their interactions and social relations, both with people inside and with outsiders. The implication is that coastal women are faced with various challenges in interactions that require communication competencies. Lack of understanding of the culture of the participants involved in the interaction will give rise to social conflict: such as quarrels, hostilities, misunderstandings and prejudices.Komunikasi itu terikat oleh budaya. Sebagaimana budaya berbeda antara satu dengan lainnya, maka praktek dan perilaku komunikasi individu-individu yang diasuh dalam budaya berbeda akan memiliki cara-cara komunikasi yang berbeda. Komunitas perempuan pesisir merupakan sub-kultur dari masyarakat Cirebon, selain memiliki karakteristik yang unik dan khas, mereka memiliki peran penting dalam membantu menambah penghasilan ekonomi keluarga nelayan. Keterlibatan perempuan pesisir di ranah publik, makin memperluas interaksi dan relasi sosialnya, baik dengan orang dalam maupun dengan orang luar. Implikasinya, perempuan pesisir dihadapkan pada berbagai tantangan dalam interaksi yang membutuhkan kompetensi komunikasi. Kurangnya pemahaman tentang budaya dari peserta yang terlibat dalam interaksi, akan melahirkan konflik sosial: seperti terjadi pertengkaran, permusuhan, salah paham dan prasangka.
Independensi Wartawan PWI Jawa Barat dalam Berita Keislaman
Authors: Novita Lisna 
Published: July 2019

This study aims to interpret the understanding of PWI West Java journalists on the concept of independence in the news, describe constructing a reality into a story, and describe the Islamic interpretation of West Java PWI journalists on Islamic news. This research is qualitative research using phenomenological methods. Data collection techniques used in this study are observation, interview and documentation techniques. The results of this study indicate that West Java PWI journalists are very understanding and important to the concept of independence but are flexible when the construction process of Islamic news is discussed, because the construction of the reporting of West Java PWI journalists is still carried out on the basis of media pressure.Penelitian ini bertujuan untuk menginterpretasikan pemahaman wartawan terhadap konsep independensi dalam pemberitaan, mendeskripsikan konstruksi sebuah realitas menjadi sebuah berita, dan interpretasi keislaman wartawan PWI (Persatuan Wartawan Indonesia) Jawa Barat terhadap berita keislaman. Penelitian ini menggunaan jenis penelitian kualitatif dengan metode fenomenologi. Teknik pengumpulan data dalam penelitian ini adalah teknik observasi, wawancara dan dokumentasi. Hasil penelitian menunjukan bahwa wartawan PWI Jawa Barat sangat memahami dan memandanag penting terhadap konsep independensi namun bersifat fleksibel saat proses konstruksi berita keislaman di laangan, karena konstruksi pemberitaan wartawan PWI Jawa Barat masih dilakukan atas dasar ketingan media.
Studi Etnografi Komunikasi pada Organisasi Persatuan Islam
Authors: Irawan Dede 
Published: July 2019

This aims to portray the organization of Persatuan Islam as a speech community. This research uses constructivist paradigm, because that will be explored is the understanding that helps the process of interpretation called the Persatuan Islam as a community specch. This study uses a qualitative research type, because that will be studied, is a central fact. Furthermore, this research using ethnography method of communication. Aside from being a research method, ethnographic communication also has the theoretical assumptions, components and tasks of communication in a speech society (Community Speech). The results of the study show that Islamic Unity communications on a common pattern, except in the cognitive aspect show the dominance of religious understanding. The use of Islamic congregation language of many pesantren. Furthermore in the interaction lesson, the congregation of Islamic unity shows a collective cohesiveness. Penelirian ini bertujuan untuk memotret organisasi Persatuan Islam sebagai komunitas tutur. Penelitian ini menggunakan paradigma konstruktivis, karena yang akan digali berupa pemahaman yang membantu proses interpretasi yang berkaitan dengan Persatuan Islam sebagai specch community. Penelitian ini menggunakan metode penelitian kualitatif, sebab yang akan dikaji, merupakan gejala sentral. Selanjutnya penelitian ini menggunakan metode etnografi komunikasi. Selain sebagai metode penelitian, etnografi komunikasi juga memiliki asumsi-asumsi teoritik berupa aktivitas, komponen dan kompetensi komunkasi pada sebuah masyarakat tutur (Speech Community). Hasil penelitian menunjukan komunikasi Persatuan Islam mengacu pada pattern umum, kecuali dalam skema kognitif menunjukan dominasi pemahaman keagamaan. Dalam penggunaan varietas bahasa jamaah Persatuan Islam banyak dipengaruhi budaya pesantren. Selanjutnya dalam kompetensi interaksi, jamaah persatuan Islam menunjukan kohesifitas kolektif.