bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systemic Treatment for Soft Tissue Sarcoma: What is Standard, What is New
Authors: Jinga D.C. , Chetroiu D. 
Published: May 2018

Abstract
Soft tissue sarcoma (STS) is a biologically heterogeneous malignancy with over 50 subtypes. This solid tumor is one of the most challenging diseases to treat for the medical oncologist. STS often forms in the body’s muscles, joints, fat, nerves, deep skin tissues, and blood vessels. The natural history of high-grade STS is characterized by a strong tendency toward local recurrence and metastatic spreading, despite optimal initial strategies. The lung is the most common site of metastases, with poor prognosis. We present the current international guidelines for the adjuvant treatment and systemic treatment for advanced STS and the new discoveries. Many new molecular targeting drugs have been tried in the last ten years, and some were approved for soft tissue sarcoma. The first approved was Imatinib, as a treatment for gastrointestinal stromal tumors (GISTs). Following Imatinib, other tyrosine kinase inhibitors (TKIs) received the approval for GISTs such as Sunitinib and Regorafenib, and Pazopanib for non-GIST soft tissue sarcomas. In 2016, FDA approved the first monoclonal antibody that targets platelet-derived growth factor receptor (PDGFR)-α, Olaratumab. The new treatment demonstrates an overall survival advantage. In this review, we aimed to summarize the results from the most recent studies on adjuvant treatment for high-grade STS and systemic strategies for advanced STS.
Pelvic Chondrosarcoma - The Role of the Biopsy and the Correlation Between the Histopathological Bioptic Diagnosis and the Excisional One
Authors: Popescu R. , Cuculici Șt. , Cristea Șt. 
Published: May 2018

Abstract
Chondrosarcoma is one of the most frequent malignant bone tumors. We included in the initial study population 110 patients with pelvis biopsies and the histopathological result of chondrosarcoma. We excluded the cases with incomplete data. Thirty-five in block resections were included in the final study population. In the rest of the cases, the surgery was not made because of many considerations (multiple metastases, patient’s refusal, and surgical contraindications). In three cases, discrepancies were noted between the grade of malignancy found after biopsy and the one confirmed through the surgical excision. This corresponds to a precision rate of 91,42 % (32/ 35) in the confirmation of chondrosarcoma. The accuracy of the histopathological diagnosis between low grade chondrosarcoma and high grade chondrosarcoma was of 94,27 % (33/ 35). We concluded that the image-guided biopsy is useful in determining the grade of malignancy of the chondrosarcoma and in the planning of the subsequent treatment. A multidisciplinary team (orthopaedic surgeon, radiologist, and pathologist) is needed to improve the diagnosis of the pelvic chondrosarcoma.
Static Balancing of Robot Mechanisms and Manipulation Devices
Authors: Segla Stefan 
Published: May 2018

Abstract
The paper deals with static balancing of various kinds of mechanisms and manipulation devices using spring balancing mechanisms. In case of parallelogram robots and manipulation mechanisms a spring balancing mechanism exerting a constant force is used. Problems of static balancing of variable payloads are also presented and investigated in the paper. Static balancing is formulated as an optimization problem with the objective function expressing minimization of the forces acting in the driving joints. As design variables geometrical variables and spring stiffnesses and their unloaded lengths are used. Optimization Toolbox for Use with Matlab and GOOD (Generator Of Optimal Designs) are used to solve the static balancing problems. The optimized mechanisms are evaluated by using multibody dynamics programs taking into account friction effects in mechanism joints. The results of static balancing optimization show essential reduction of the gravity load in drive joints and consequently driving forces with important energy savings.
“East meets West” – on studying “Eastern” housing estates through “Western” concepts and approaches
Authors: Andráško Ivan 
Published: May 2018

AbstractThis paper is directly associated with the international conference “East meets West – contemporary urban issues revisited”.The main objective of the paper is to provide readers with ideas related to the possibility of studying the “Eastern” (post-socialist) housing estates through selected “Western” concepts including representation, symbolism, everydayness/everyday life and the complexity of relations including the materiality or socio-technical configuration of places.The paper consists of three main sections: in the introductory section, basic information and knowledge regarding (large) housing estates are concisely presented and discussed. By means of illustrative examples, the second main section of the paper covers a brief presentation of selected “Western” concepts. The final section focuses on the discussion of the concepts’ usefulness and of the methods through which they can be utilised. The main ideas and conclusions resulting from this paper can be stated as follows:–particular housing estates in CEE countries find themselves in a common, yet at the same time always in one way or another specific and individual “post-socialist situation”;–to understand the situation of a particular housing estate means to understand the structural influences as well as the agency of particular (local) actors, either human or non-human;–housing estates can be seen as dynamic, ever-changing socio-technical-spatial formations constantly passing through a continuous process of (re) production by various forces/actors and (power) relations.
Living memorial and frozen monuments: the role of social practice in memorial sites
Authors: Erőss Ágnes 
Published: May 2018

AbstractMonuments and memorials have become mundane elements of public space: commemorative plaques, statues, and memorial sites are mushrooming in the wake of memory production. However, besides the emblematic ones that have become accepted both by the powers and the public, there is a long list of monuments which are less cherished and/or have failed to be accepted as landmarks. When analysing two memorials in Budapest, I was interested in the possible factors explaining the failure and/or neglect of a monument. The monument dedicated to the victims of the German Occupation of Hungary was never officially unveiled, thus has not become part of the governing authority’s political landscape. Hence the proliferation of commemorative plaques on site the Corvin Passage, one of the emblematic scenes of 1956 revolution in Hungary, seems to be in a limbo between a commercial area and a heritage site. In contrast, the anti-monument on Liberty Square, a collage of personal relics, juxtaposing the official memorial, regularly visited by locals as well as tourists.Based on the example of the anti-monument on Liberty square, I stress the importance of social practice in commemoration. I argue that a memorial site’s public acceptance and success is correlated with its capacity to engage in regular social practices.
Bitola – from Eyalet capital to regional centre in the Republic of Macedonia
Authors: Dimitrov Nikola V. , Markoski Blagoja , Radevski Ivan , Zlatanoski Vladimir 
Published: May 2018

Abstract
In the past nine hundred years Bitola has undergone a string of administrative and political rises and falls. In the course of the 16th century the city grew to have a very large population and become a huge economic and geopolitical centre of the large province of Rumelia in the Ottoman Empire. However, as a result of some overwhelming political and military events that played out during the 20th century (the dissolution of the Ottoman Empire, the Balkan wars, WW1, WW2 and other economic, political, technical and technological developments that occurred in the world and in the country) Bitola was reduced to a mere local city in economic, geopolitical and population terms. The immediate economic and population expansion of Bitola is presented through an exact numeric and cartographic overview of spatial-temporal changes in the city’s development in the past two centuries. For the purposes of rendering a more accurate image, we have compared Bitola’s population, administrative and geopolitical role with a number of major Balkan cities.
RANCANG BANGUN SISTEM MONITORING ARUS BEBAN PADA GARDU DISTRIBUSI MENGGUNAKAN SHORT MESSAGE SERVICE
Authors: Indra Parmana Ignatius I Wayan Rexci , Partha Cok Gede Indra , Utama Ngakan Putu Satriya 
Published: May 2018

Gardu distribusi merupakan komponen utama dari sistem distribusi tenaga listrik. PLN sebagai penyedia kebutuhan listrik di Indonesia masih menggunakan cara konvensional dalam memonitor arus beban pada gardu distribusi dengan datang ke lokasi dan mengambil data. Rancang bangun sistem monitoring arus beban pada gardu distribusi menggunakan SMS merupakan perangkat yang diintegerasikan pada gardu distribusi. Nilai arus beban yang dibaca dan dikonversi oleh sensor, informasi waktu dan tanggal secara real time ditampilkan pada LCD. Pengimplementasian sistem monitoring arus beban dilakukan pada gardu distribusi KA-0298 yang menyuplai Laboratorium Teknik Elektro Universitas Udayana. Perangkat ini dapat melakukan monitoring arus beban berdasarkan perintah yang dikirimkan melalui SMS. Perintah SMS yang dikirim dengan kode “CEKARUS” dapat diterima dan direspon oleh sistem monitoring arus beban dengan hasil balasan SMS informasi nilai arus beban fasa R, fasa S, fasa T dan fasa N pada gardu distribusi. Sistem data logger pada perangkat dapat digunakan untuk merekam perubahan arus beban pada gardu distribusi. Sistem notifikasi arus beban memberikan SMS peringatan jika terjadi gangguan arus beban pada gardu distribusi.
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Rancang Bangun Sistem Smart Charging menggunakan Panel Surya pada Robot 6WD berbasis Mikrokontroler Arduino
Authors: Hendrayanto Made Yogi , Swamardika Ida bagus Alit , Mertasana Putu Arya 
Published: May 2018

Ilmu pengetahuan dan teknologi dalam bidang robotika pada saat ini berkembang dengan sangat cepat. Teknologi robotika pada dasarnya dikembangkan dengan tujuan untuk membantu manusia dalam melakukan pekerjaan tertentu, seperti pekerjaan yang berisiko tinggi, pekerjaan yang tidak bisa dikerjakan oleh tangan manusia secara langsung dan pekerjaan yang membutuhkan ketelitian tinggi. Pada saat ini, robot masih dikendalikan secara manual oleh manusia menggunakan Baterai sebagai sumber energi robot dan melakukan pengisian secara manual. Berdasarkan hal tersebut maka ada suatu keinginan untuk berkontribusi dalam pengembangan teknologi robot 6WD yaitu dengan merancang sebuah sistem Smart charging menggunakan Panel surya sebagai sumber energi untuk melakukan pengisian baterai robot secara langsung. Sistem yang dibuat, nantinya dapat membuat robot 6WD, bergerak dengan cara manual menggunakan inputan dari komputer yang dikontrol manual dari manusia. Manusia hanya perlu menggerakkan dan dapat melihat kondisi dari 2 buah baterai robot 6WD dari Komputer, kemudian komunikasi yang terjadi antara komputer dengan robot dapat dilakukan secara dua arah, agar robot dapat memberikan informasi balik kepada komputer, baik itu daya baterai, loss area dan lain sebagainya.Arduino Mega 2560 digunakan sebagai sistem utama yang mengolah semua data input dan output pada sistem. Modul HM-TRP befungsi untuk mengirimkan data dari robot ke komputer untuk ditampilkan.Pengiriman informasi robot 6WD meliputi informasi kondisi status 2 buah baterai, arus baterai, tegangan baterai, dan arah dari gerakan robot yang akan dikendalikan melalui GCS(Ground Control Station).

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CADANGAN PREMI ASURANSI JOINT-LIFE DENGAN SUKU BUNGA TETAP DAN BERUBAH SECARA STOKASTIK
Authors: SUKANASIH NI KOMANG , WIDANA I NYOMAN , JAYANEGARA KETUT 
Published: May 2018

Joint life is an insurance that covered two or more individuals in one policy. This research aims to determine the value and comparison of fixed deposit rate premium and stochastic rate with Vasicek model. It used prospective calculation method. The mortality table in the research used TMI-2011, for participant were couple age 40 and 35 years old with 10 year premium payment. Under this condition the value of constant rate premium and Vasicek rate premium is and . Besed of this research showed the value of the Vasicek rate premium is smaller than constant rate premium.
ANALISIS MISKONSEPSI “GERAK DAN GAYA” MENGGUNAKAN INSTRUMEN FORCE CONCEPT INVENTORY (FCI) PADA MAHASISWA CALON GURU FISIKA
Authors: Munfaridah Nuril , Sutopo Sutopo , Sulur Sulur , Asim Asim 
Published: May 2018

Tujuan penelitian ini adalah memetakan penguasaan konsep dan mengetahui miskonsepsi mahasiswa calon guru fisika terkait materi gerak dan gaya menggunakan instrumen Force Concept Inventory (FCI). Pengambilan data dilakukan dengan memberikan tes kepada mahasiswa calon guru fisika tahun pertama di Jurusan Fisika UM sebanyak 95 mahasiswa. Hasil analisis jawaban dari instrumen yang diberikan menunjukkan kecenderungan bahwa sebagian besar mahasiswa masih mempercayai pemikiran logis yang berdasar pada kuantitas fisik dan belum menggunakan konsep fisika untuk menjawab. Beberapa konsep fisika terkait dengan gerak dan gaya yang cukup dikuasai oleh mahasiswa antara lain gerak melingkar, gerak parabola, hukum II Newton, dan hukum III Newton, sedangkan konsep yang masih perlu diberikan penguatan lebih diantaranya gerak vertikal baik ke atas maupun ke bawah dan kebeadaan gaya kontak dan interaksi gaya benda satu dengan benda yang lain. Setelah diperoleh pemetaan penguasaan konsep dan miskonsepsi mahasiswa calon guru fisika, perlu dikembangkan strategi pembelajaran yang dapat menyelesaikan permasalahan miskonsepsi mahasiswa berdasarkan karakteristik masing-masing materi fisika.
TOXICITY OF THE ORGANIC EXTRACT FROM Annona muricata L. (ANNONACEAE) SEEDS ON Brevicoryne brassicae (L.) (HEMIPTERA: APHIDIDAE) IN CABBAGE CULTIVATION (Brassica oleracea L.)
Authors: Paz Luan Carlos , Soares Ariane Morgana Leal , Teixeira Raiza Rocha Oliveira , Silva José Pedro , Ferreira Caio Henrique Loureiro de Hollanda , Trindade Roseane Cristina Predes 
Published: May 2018

O artigo teve como objetivo avaliar a toxicidade dos extratos produzidos a partir de sementes de Annona muricata seca sobre Brevicoryne brassicae no cultivo de couve (Brassica oleracea). Foram utilizadas quatro caldas para pulverização: água acrescida de adjuvante (®Tween 80), água com inseticida ®Decis 25 EC, água acrescida de extrato hexânico e água acrescida de extrato etanólico, ambos de Annona muricata, avaliando a mortalidade de Brevicoryne brassicae após 2 e 24h de pulverizadas. Os testes foram feitos de 3 formas: pulverização em contato direto com o inseto, pulverização em superfície natural (folha de couve) e pulverização em superfície artificial (papel). Foram utilizados 5 insetos em cada placa de Petri, em 6 repetições por tratamento, num esquema fatorial 4 (caldas) x 2 (tempos). Para as ações testadas não houve uma diferença estatística entre os extratos e o produto químico comercial, porém o extrato hexânico de sementes secas de Annona muricata apresentou o melhor potencial ação inseticida a Brevicoryne brassicae em plantas de couve (Brassica oleracea L.).
Effects of deficit irrigation on the potato tuber development and quality
Authors: GÜLTEKİN Rohat , ERTEK Ahmet 
Published: May 2018

This study was conducted to determine the effects of deficit irrigation on tuber growth and quality of potato (Solanum tuberosum L.). Certified seeds of potato variety “Agria” were used as study material. Irrigation treatments was consisted of one irrigation interval (5 days) and five different levels (I100, I85, I70, I55, I40) of soil water deficit measured before irrigations. First irrigation was applied by drip irrigation up to field capacity the soil water content in 0-60 cm depth in all treatments. Subsequent irrigations were applied according to the treatments.

The irrigation water and evapotranspiration (ET) values of treatments ranged from 243.0 to 311.9.4 mm and from 337.1 to 385.9 mm in the first year, respectively, and from 166.7 to 223.2 mm and from 204.0 to 255.7 mm in the second year, respectively. Yields varied from 30.85 to 47.13 t/ha in the first year and from 28.77 to 44.45 t/ha in the second year. The yields were decreased based on water deficit levels. The highest yields were obtained from I100 treatment.

The results have indicated that water restriction had a significant effect on yield, single tuber weight, percentage of marketable tuber, plant length, mean tuber length, mean tuber diameter and percentage of tuber peeling. The results were showing that the I100 treatment in especially was of the most importance for the highest percentage marketable tuber and tuber yield obtained per unit water applied. Therefore, the I100 treatment can be recommended for potato cultivation under similar climatic and soil conditions.
Changing Rural Livelihood Strategies in the Community of Goljung, Rasuwa
Authors: Rai Dhyanendra Bahadur 
Published: May 2018

Different patterns of livelihood are found in different places within same community or different communities over the generation. Therefore livelihood strategy is a changing process of an individual or a household level of economic and social activities in order to fulfill daily livelihood needs. This paper seeks to explore the changing rural livelihood strategies of a community in mountain region of Nepal. The study is mainly based on primary data collected from field survey, focus group discussion (FGD) and key informant interview (KII). Questionnaire survey was conducted within 52 households by applying random sampling method. Likewise five KII and three FGDs were conducted and participants belonged to different field i.e. ward chairperson, ward women member, businessmen, wage labor, farmer and social worker. The finding indicates that livelihood strategies are changing rapidly in the rural areas. Similarly, multiple sources of income of a household have resulted into secured livelihood system in Goljung. Despite the fact that the agriculture with livestock farming was an important traditional source of livelihood in the past, the roles of non-agricultural sectors have become significant for livelihood sustaining in the rural community in Goljung, Rasuwa in the present days. After a decade, development of the hydro-electricity projects and trade route between Nepal and China has played the catalyst role for changing rural livelihoods of local people in this village. The Third Pole: Journal of GeographyVol. 17: 20-36, 2017
Spatial Variation in the Level of Agricultural Development in Districts of Western Development Region, Nepal
Authors: Dhakal Bhola Nath 
Published: May 2018

In the present paper an attempt has been made to assess the spatial variation in the level of agriculture development in the Western Development Region of Nepal. Nine variables are used in determining the level of agricultural development. Those are net sown area, cropping intensity, crops productivity, irrigated area, use of High Yield Variety (HYV) seeds, chemical fertilizer (NPK) consumption, agricultural implements, agricultural labours and support from commercial and development banks. Besides, districts are classified as their respective categories viz. high, medium and low on the basis of scores (like mean and SD) of these variables. These analyses have been carried out by transforming and combining the data related to nine variables, using ‘Z’ score to get the composite ‘Z’ score. On the basis of composite score, developments of districts have been again categorized into three categories i.e. high, medium and low. On an aggregate four districts range their composite Z-score value above 0.1, are highly developed districts, six districts fall under medium category (value ranged from -0.25 to 0.1) and remaining six districts lie under low category having their composite Z-score below -0.25. The Third Pole: Journal of GeographyVol. 17: 59-72, 2017
PROF. DR. MUHARREM ERGİN'İN HAYATI, ESERLERİ VE TÜRK DİLİ'NE KATKILARI
Authors: BULUT Serdar 
Published: May 2018

Muharrem
Ergin, Haydar Ergin ile Naime (Nüfus kaydında Hanım) Ergin’in oğlu olarak
1339/1923’te Ahıska vilayetinin Ahılkelek kazasına bağlı Gögye köyünde
doğmuştur. Muharrem
Ergin’in ailesi arasındaki adı Behram’dır. Ancak nüfusta adı Muharrem Ergin olarak geçmektedir. Muharrem Ergin’in ailesi daha sonra Muş vilayetinin
Bulanık kazasına yerleşmiştir. Muharrem
Ergin’in on kardeşi vardır. Göç sırasında aile bölündüğü için karışık bir aile
tablosu karşımıza çıkmaktadır. Muharrem Ergin etnik yapı olarak Türkiye’de “Mesket Türkleri” olarak bilinen
Terekeme veya Karapapak Türklerindendir.Çalışmamızda Orhun Abideleri'nün ünlü dilcilerinden Muharrem Ergin'in hayatı ve edebi kişiliği ve eserleri hakkında bilgi verilecektir. Bu bilgilerden sonra çalışmamızın en önemli kısmı ise Muharrem Ergin'in Türk diline sağlamış olduğu katkılar olacaktır. Burada Muharrem Ergin'in Türk Dili'ne sağlamış olduğu katkılar ayrı ayrı verilmeye çalışılacaktır.
ÜSTÜ-HÜRE FESTİVALİ: TUVALARIN DİNİ İNANIŞLARI VE HALK MÜZİĞİ
Authors: Kulmanova Aidana 
Published: May 2018

Tuva
Türkleri, Budist ve şamanist olmak üzere iki dini inanca sahiptir. Günümüzde
Tuva Budizm’i resmi din olarak kabul eden tek Türk topluluğudur. Budizm ve
Şamanizm’in bir arada uyum içinde yaşamasındaki en büyük etken, Tuvaların
tabiata duyulan saygıdır. Tuva’da Sovyetler Birliğinin ardında yapılan
Üstü-Hüre Festivalinde dini inanşların yeniden canlanması, bir hayat tarzının
başlangıcı olmuştur. Üstü-Hüre Festivali’nin kutlanması SSCB döneminde, ne
geldikleri yöreden, ne oraya ait deneyimlerinden ne de inanşların kendine özgü
yapısından bağımsız olamamıştır. Geleneğin yeniden üretimi sürecinde bir
taraftan bir şeyler yeniden üretilerek geleceğe aktarılırken diğer taraftan
ortaya çıkan yeni şartlar biçiminde gerçekleşen yeniden üretim nedeniyle
gelecek özgün bir formda inşâ olmaktadır. Bu çalışmada, SSCB sonrası döneminde
yeniden canlandırılan Üstü-Hüre Festival’i araştırılmaktadır.

Üstü-Hüre,
Tuvaların kültürel-dini pratiklerden yola çıkılarak şamanizm ve Budizm bir arada kutlanan festivaldir. Bu festivalde,
Tuvaların söylenen modernleşen müzikleri ve yapılan dini inanışları da yazılacaktır.
Makalenin yazınsal incelenmesinde Tuva ve Rusya araştırmacıları hariç Batı
seyahatçileri tarafından yapılan çalışmaları da içerir. Bununla birlikte, 8-28
Temmuz 2017 yılının arasında Tuva’da yapılan alan araştırmalarına
dayanılmaktadır.
Giresun İli Yangın İstatistiklerinin İncelenmesi (2011-2016)
Authors: BEKEM KARA İlknur 
Published: May 2018

In this study, fire statistics in Giresun were
considered in 2011-2016 period, distribution of fires by years, burning place
according to the building material, fireman's intervention situation and the
causes of fire exits have been researched.
Statistical distribution of fires by month was established taking the
sample of 2012. In addition, home fires,
which have the greatest amount of all fires, are examined. As a result, A total
of 842 fire incidents took place in Giresun between 2011 and 2016, in the first
place for the reasons of fire exit, the electrical contact, in the second place
the chimney burning takes place, 43% of the fires were initially extinguished,
in the first 3 months of the 2012 year, the chimney fires are high, most of the
house fires have been found in reinforced concrete structures. Finally,
proposals have been made for the reduction of fire incidents.