bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supporting caregivers within caregiver‐mediated interventions: a commentary on Brown et al. (2024)
Authors: Edmunds Sarah R. , Hock Robert 
Published: November 2024

A substantial portion of interventions designed to support autistic children are also designed to be delivered by caregivers (i.e. are ‘caregiver‐mediated’). Brown et al. (Journal of Child Psychology and Psychiatry, 2024) are one of the first groups to critically examine the baseline skills that caregivers bring as they prepare to learn a class of interventions called Naturalistic Developmental Behavioral Interventions (NDBIs), which are designed to support social communication growth in young autistic children. This commentary commends Brown and colleagues for their focus on caregivers, a linchpin within the increasingly prominent caregiver‐mediated process of intervention delivery. However, it is imperative that future research understand the potential adverse effects and supports that are needed to bolster caregivers in this crucial role. We present six recommendations for research on caregiver‐mediated interventions that build on Brown and colleagues' work and address these needs, which involve: caregiver supports, equitable samples, community settings, adaptive designs, general principles, and implications for NDBI dissemination.
Flood fragility and vulnerability functions for residential buildings in the Province of Leyte, Philippines
Authors: Besarra Isaac , Opdyke Aaron , Aquino Diocel Harold , Santiago Joy , Mendoza Jerico E. , Lagmay Alfredo Mahar Francisco A. 
Published: November 2024

AbstractThe Philippines experiences frequent flooding, but, despite expansive tools for risk reduction, there remain gaps in understanding generalised relationships between flood events and damage to residential structures for regions outside the nation's capital. This gap has limited the ability to model flood risk and damage without robust functions to link hazards and housing vulnerability. This research draws on 394 household surveys to empirically derive a suite of flood fragility and vulnerability functions for residential structures in the Province of Leyte for light material, elevated light material and masonry structures. The results showed that masonry construction was more resilient to floods compared to light material counterparts. Elevated light material structures also exhibited lower damages at low inundations but tend to fail abruptly at flood depths greater than 3 m. By empirically deriving flood damage functions, the findings contribute to a more localised approach to quantifying housing vulnerability and risk that can be used for catastrophe and risk modelling, with applications for government agencies, the insurance industry and disaster risk researchers. This research lays the foundation for future flood risk mapping with growing significance under climate change.
The unspoken experiences of systemic supervisors of color: A modified Delphi study
Authors: Anderson Leslie A. , Notice Maxine , Armstrong Joslyn , Smith Karmen R. 
Published: November 2024

AbstractDespite collective conversations about the need for more racial diversity, the field of couple/marriage and family therapy (C/MFT) continues to be occupied predominantly by White individuals. Within the C/MFT literature, several scholar–practitioners have highlighted what the lack of racial representation means for our profession and, more importantly, our clients. C/MFT scholars have also shed light on the distinctive experiences of racially minoritized students and therapists traversing a racially homogeneous discipline. However, a smaller, and often overlooked, demographic in these conversations is supervisors of color. This modified Delphi study enlisted the expert perspectives of eight supervisors of color who each have at least a decade of supervisory experience. Consensus among the panelists emphasized the unique, but often inadequate training needs for supervisors of color and the sociocultural factors that often affect the supervisory relationship. This study provides implications that are critical to fostering the professional development of systemic supervisors of color.
Melasma Management: A Comprehensive Review of Treatment Strategies Including BTX‐A
Authors: Kania Barbara , Lolis Margarita , Goldberg David 
Published: November 2024

ABSTRACTBackgroundBotulinum toxin A (BTX‐A) is a widely utilized protein derived from the bacterium Clostridium botulinum, known for its effectiveness in treating various medical conditions involving muscle spasticity, involuntary muscle movements, and pain disorders. Beyond its therapeutic applications, BTX‐A is also commonly used in cosmetic procedures to address dynamic wrinkles, hyperhidrosis, sebum production, pore size, and overall skin texture. While the use of neurotoxins like BTX‐A for treating conditions such as UVB‐induced hyperpigmentation, specifically melasma, is an emerging area of interest, it is not yet a widely recognized treatment for this dermatologic condition. This literature review serves to provide a consolidated overview of the current therapeutic implications of BTX‐A treatment for melasma and explore its proposed mechanisms of action.ObjectiveThis review aims to provide a comprehensive analysis of the current evidence base for the efficacy of BTX‐A treatment on melasma.MethodsTo gain a comprehensive understanding on the current theories regarding BTX‐A treatment on melasma, a literature review was conducted on all the available information using PubMed. A combination of keywords was used to maximize the search results, including “botulinum toxin,” “melasma,” “melanogenesis,” “neurotoxin,” “cholinergic system,” “BTX‐A,” and “UV‐induced melasma.” The search was not restricted by date, allowing for the inclusion of articles offering historical context and those providing the most recent findings. Ninety‐eight articles were reviewed to provide a consolidated update on the effectiveness of botulinum toxin A in reducing the appearance of melasma and potential mechanisms of action involved in doing so.ConclusionMelasma is a challenging dermatologic condition due to its chronicity and various intrinsic and extrinsic factors that influence its pathogenesis. While current treatment options for melasma include topical, oral, and light‐based therapies, recent studies suggest that BTX‐A may hold potential as a viable treatment modality for melasma. Despite the mechanism of action remaining unclear, it is hypothesized that BTX‐A inhibition of Ach receptors on melanocytes could play a role in the reduction of melanogenesis. BTX‐A treatment in melasma‐affected skin demonstrates statistically significant reduction in hyperpigmented lesions associated with melasma.
Hip surveillance in cerebral palsy: Review of clinical practice in a tertiary children's hospital using electronic health record linkage
Authors: Sorhage Alexandra , Stott Ngaire Susan 
Published: November 2024

BackgroundChildren with cerebral palsy (CP) can develop neuromuscular hip dysplasia (NHD) and radiographic surveillance is recommended, guided by gross motor function classification system (GMFCS) level. This study evaluated the clinical practice of hip surveillance for NHD in a children's hospital and risk factors for abnormal first and subsequent X‐rays.MethodHealth data were extracted for 159 participants with CP, 98 male, 52 GMFCS level IV or V (birth years 2008–2018) and linked to electronic radiology datasets.ResultsThe median age at diagnosis of CP was 18 months (1–96 months). Thirty‐eight participants had X‐rays prior to diagnosis and 10 (6%) had no X‐ray. Seventy‐nine of 111 children classified as GMFCS levels II to V (71%) met both 2008 and 2020 Australian Hip Surveillance Guidelines (AHSG) having the first hip X‐ray by 24 months of age. Sixteen participants (11%) had abnormal first hip X‐ray (subluxation or migration percentage >30% in 14; MP 90%–100% or dislocation in 2). Univariate analyses showed NHD (MP > 30%) or dislocation at first X‐ray was associated with GMFCS IV or V (OR = 6.98 (2.12–22.94), P = 0.001); >4 months between diagnosis and first hip X‐ray (OR = 5.60 (1.52–20.59), P < 0.0009) and more common in NZ Māori children than non‐Māori children (OR = 3.71 (1.25–11.01), P = 0.012).ConclusionSurveillance for NHD did not follow guidelines in almost a third of children, with delays in screening associated with greater risk of NHD at first X‐ray. Inequities found for Indigenous NZ Māori children with CP require further investigation and stakeholder consultation.
Accuracy of International Guidelines in Identifying Normal Liver Histology in Chinese Patients With HBeAg‐Positive Chronic HBV Infection
Authors: Jia Yidi , Qi Xun , Yu Xueping , Dong Minhui , Wu Jingwen , Li Jing , He Jingjing , Ma Zhenxuan , Zhang Xueyun , Xie Yiran , Guo Yue , Mao Richeng , Huang Yuxian , Li Fahong , Zhu Haoxiang , Zhang Jiming 
Published: November 2024

ABSTRACTWe evaluated the diagnostic accuracy of various international guideline criteria for identifying HBeAg‐positive chronic HBV infection patients with no significant liver disease. A total of 1108 HBeAg‐positive CHB patients were retrospectively enrolled. The guidelines assessed included those from the European Association for the Study of the Liver (EASL) 2017, the American Association for the Study of the Liver Disease (AASLD) 2018, the Asian Pacific Association for the Study of the Liver (APASL) 2015 and the Chinese Society of Hepatology (CSH) 2022. The CSH criteria demonstrated a higher proportion of patients with G0‐1 and S0‐1 (82.9%) compared to the EASL (75.9%), AASLD (75.3%) and APASL groups (58.8%). Additionally, the CSH criteria exhibited a significantly higher predictive value (AUC 0.782, 95% CI 0.754–0.809) than the EASL (AUC 0.765, 95% CI 0.737–0.793), AASLD (AUC 0.749, 95% CI 0.720–0.778) and APASL (AUC 0.720, 95% CI 0.690–0.750) criteria for identifying G0‐1 and S0‐1. Adding quantitative HBsAg levels (> 104 IU/mL) to the EASL, AASLD and APASL criteria improved diagnostic performance. Consequently, the CSH guideline thresholds showed higher accuracy in identifying Chinese HBeAg‐positive patients with no significant liver disease compared to EASL, AASLD and APASL criteria, emphasising the importance of considering quantitative HBsAg in the evaluation of HBeAg‐positive chronic HBV infection.
Smartphone Application Intervention on Obstructive Sleep Apnea Among Overweight and Obese High‐Tech Employees: A Randomized Controlled Trial
Authors: Lin Mei‐Hsiang , Chen Ning‐Hung , Ho Lun‐hui , Liou Miaw‐Jene , Hsu Hsiu‐Chin 
Published: November 2024

ABSTRACTThe aim of this study was to examine the effectiveness of an adjusting lifestyle intervention with a smartphone application (app) in managing obstructive sleep apnea (OSA) among overweight and obese high‐tech employees. A 6‐months three‐armed randomized controlled trial was employed. A total of 144 eligible participants were randomly allocated into the smartphone app ‘MyFitnessPal’ plus education (MFPE; n = 48), ‘MyFitnessPal’‐only (MFP‐only; n = 50) and the control group (n = 46) at a 1:1:1 ratio. The data were collected using related questionnaires and portable sleep monitor. Generalized estimating equation was used to analyze data. Results revealed that there was a significant interaction between time and group in BMI (Wald χ2 = 4.47, p = 0.04) in the MFPE after the 12th week of the intervention. Nevertheless, there was no significant interaction between group and time observed in apnea‐hypopnea index (AHI) score after 24 weeks of intervention. The adjustment lifestyle integrated with an app may offer a simple and cost‐effective approach. The findings of this study may provide precious information for occupational healthcare providers, facilitating health promotion in the workplace for overweight employees with OSA.
Turnip mosaic virus selectively subverts a PR‐5 thaumatin‐like, plasmodesmal protein to promote viral infection
Authors: He Rongrong , Li Yinzi , Bernards Mark A. , Wang Aiming 
Published: November 2024

Summary
Pathogenesis‐related (PR) proteins are induced by abiotic and biotic stresses and generally considered as part of the plant defense mechanism. However, it remains yet largely unclear if and how they are involved in virus infection. Our recent quantitative, comparative proteomic study identified three PR‐5 family proteins that are significantly differentially accumulated in the plasmodesmata (PD)‐enriched fraction isolated from Nicotiana benthamiana leaves infected by turnip mosaic virus (TuMV).
In this study, we employed the TuMV‐Arabidopsis pathosystem to characterize the involvement of two Arabidopsis orthologs, AtOSM34 and AtOLP of the three N. benthamiana PR‐5‐like proteins.
We show that AtOSM34 and AtOLP are PD‐localized proteins and their expression is up‐ and downregulated in response to TuMV infection, respectively. Deficiency or overexpression of AtOLP does not affect viral RNA accumulation. Knockdown of AtOSM34 inhibits TuMV infection, whereas its overexpression promotes viral infection. We further demonstrate that AtOSM34 functions as a proviral factor through diminishing PD callose deposition to promote viral intercellular movement, targeting the viral replication complex to enhance viral replication, and suppressing the ROS‐mediated antiviral response.
Taken together, these data suggest that TuMV has evolved the ability to selectively upregulate and subvert AtOSM34, a PR‐5 family protein to assist its infection.
Capital and income breeders among herbs: how relative biomass allocation into a storage organ relates to clonal traits, phenology and environmental gradients
Authors: Harris Timothy , Kučerová Andrea , Bitomský Martin , Bartušková Alena , Lubbe Frederick Curtis , Klimešová Jitka 
Published: November 2024

Summary
Perennial herbs of seasonal climates invest carbon into belowground storage organs (e.g. rhizomes) to support growth when photosynthetic acquisition cannot cover demands. An alternative explanation interprets storage allocation as surplus carbon that is undeployable for growth when plants are limited by nutrients/water. We analysed relative investments to rhizomes to see to which of these explanations they align, and asked whether they scale with biomass of aboveground organs in individual species and whether clonal growth traits, phenology or environmental conditions explain investment among populations or species.
We measured biomass of rhizomes, aboveground stems and leaves in 20 temperate herbaceous perennial species, each at two localities, establishing allometric relationships for pairs of organs. We correlated relative rhizome investment with clonal traits, environmental gradients and phenology, across species.
For pairs of organs, biomass typically scales isometrically. Interspecific allocation differences are largely explained by phenology. Neither interspecific nor intraspecific differences were explained by clonal traits or environment.
Storage organs of perennial herbs do not comprise deposition of carbon surplus, but receive greater allocation in capital breeders (early‐flowering), than among income breeders (late‐flowering) relying on acquisition during growing season. Capital and income breeders in plants deserve further examination of benefits/costs.
The Cost of Managerial Caring: Exploring Identity Work in the Hybrid Work Context
Authors: Taskin Laurent , Terlinden Laurianne , Coster Stéphanie , Ajzen Michel 
Published: November 2024

ABSTRACTThe Covid crisis and the resulting enforced teleworking have significantly shaken up the manager's role, leading to increased identity work. This article draws on a longitudinal study of managers conducted over the course of a full year during the Covid crisis, from May 2020 to June 2021, using interviews and self‐administered diaries to reveal a distinct sequence of identity work. This sequence combines a reappropriation of the humane dimension inherent to the manager's role (expectations and practices of managerial caring) and a distancing from the team and the managerial role through disembodied management (cost of caring). We discuss these results by identifying a paradox of managerial caring which, translated in terms of identity, may help understanding the contemporary withdrawal tendencies among managers.
Impact of proxymetacaine on the dynamics of cyclopentolate in White 6‐ to 7‐year‐olds
Authors: Doyle Megan , O'Dwyer Veronica , Harrington Síofra 
Published: November 2024

AbstractPurposeThis study compared the efficacy of cyclopentolate hydrochloride at 10‐, 20‐ and 30‐min post‐instillation in White 6‐ to 7‐year‐olds, with and without prior instillation of proxymetacaine hydrochloride. The primary aim was to determine if accurate autorefraction values can be obtained sooner than the current standard of 30‐min post‐cycloplegia. The secondary aim was to investigate whether proxymetacaine hydrochloride enhances the efficiency of cyclopentolate.MethodsParticipants were 112 White 6‐ to 7‐year‐olds from the Child Eye Health Study. The right eye received 0.5% proxymetacaine hydrochloride and 1.0% cyclopentolate hydrochloride, and the left eye received only 1.0% cyclopentolate hydrochloride. Non‐cycloplegic and cycloplegic refractive error (at 0, 10, 20 and 30 min) was measured using a binocular, open‐field autorefractometer. Data were analysed through paired t‐tests, concordance analysis, linear regression, equivalence testing and Bland–Altman analysis, using the 95% limits of agreement.ResultsMean spherical equivalent refraction (SER) (SD) in the right eye at 0‐, 10‐, 20‐ and 30‐min post‐instillation was 0.62 (1.45) D, 1.52 (1.80) D, 1.64 (1.81) D and 1.72 (1.80) D, respectively. Mean left eye SER (SD) were 0.68 (1.24) D, 1.42 (1.66) D, 1.56 (1.66) D and 1.68 (1.72) D, respectively. Bland–Altman analysis showed a high level of agreement, and equivalence testing confirmed that there was no clinically significant difference in SER at 20 and 30 min in both eyes (within ±0.50 D), with mean differences of 0.08 (0.23) D in the right eye and 0.13 (0.30) D in the left eye (p = 0.21). However, SER at 10 and 30 min were equivalent in the right eye only.ConclusionsAccurate autorefraction values can be obtained 20‐min post‐instillation of 1.0% cyclopentolate in white children aged 6–7 years, potentially reducing clinical testing times. Proxymetacaine pre‐instillation allows for reliable measurements as early as 10‐min post‐instillation of cyclopentolate. Further research is needed to validate these findings in non‐White populations and to determine the safe discharge time post‐proxymetacaine instillation.
Neurophysiological mechanisms underlying the influence of motivational intensity on emotion regulation choice
Authors: Yan Xinyu , Gao Wei , Yang Jiemin , Campanella Salvatore , Yuan Jiajin 
Published: November 2024

AbstractMotivation is considered a crucial factor in determining emotion regulation choice (ER choice). Our previous study revealed that increased motivation led to a preference for distraction over reappraisal due to the narrowed attention, yet neural underpinnings supporting this phenomenon remain unclear. In this study, we used event‐related potentials (ERPs) to investigate whether motivation influences ER choice by early attention processing (P2) or late resource engagement (LPP). EEG activities were recorded for the pictorial contexts varying in motivational intensity and direction, while participants (N = 68) were required to decide which strategy from the two options they would use to regulate their emotions. Consistent with previous studies, the results indicated that individuals chose more distraction over reappraisal in high‐withdrawal motivated contexts while a reversed pattern was observed in low‐withdrawal motivated contexts. Moreover, high‐intensity motivated emotional contexts result in enhanced P2 and LPP. Further analysis indicates that only frontal P2 and the early LPP mediate the effect of motivational intensity on ER choice. These findings suggest that heightened motivation leads to a preference for distraction over reappraisal during emotion regulation due to the greater occupation of attentional resources.
Policy Reforms of Justice Reinvestment: Differences Between a Sample of US States' Implementations
Authors: Dollar Christopher W. 
Published: November 2024

ABSTRACTDuring the last two decades the United States federal government has promoted the Justice Reinvestment Initiative (JRI), a technical assistance program to help states implement reinvestment programs. However, much of the literature does not detail what kinds of reforms have been passed in these programs. This study seeks to answer the question: do JRI states have differing legislative focuses? One state from each U.S. Census region was selected based on their year of Justice Reinvestment Initiative program implementation during the study period (January 2004 to December 2020). Results of thematic analyses indicate that great variation exists in the 35 legislative bills that implemented justice reinvestment principles between the four states. Many have prioritized sentencing reforms and supervision enhancements to achieve implementation goals. Additionally, each of the reinvestment programs were revised at least once, with initial reinvestment strategies focusing on tough‐on‐crime priorities and their revisions moving substantially toward rehabilitation. Finally, no state legally earmarked reinvestment funds for the original purpose of justice reinvestment, community development. Policymakers and researchers alike should use an abundance of caution when comparing states' justice reinvestment successes or failures, as states have unique programs policies may contain critical differences that may affect their success.
From cognitive processes to discursive practices: Taking a critical discursive psychology approach to refugee and asylum seeker integration
Authors: Parker Samuel 
Published: November 2024

AbstractMuch of the research in social and cultural psychology on refugee integration or acculturation has tended to adopt a socio‐cognitive approach which assumes this to be a ‘process’ with a defined outcome that can be measured as successful or not. Such approaches tend to overlook the rhetorical function of talk about integration and in this article I show how research from a critical discursive psychology perspective in relation to refugees and asylum seekers has typically focussed on media, political and lay discourses about refugees. However, more recent research has focussed on analysing the talk of refugees themselves which I will show points towards the importance of shifting how refugee integration is considered and that taking a critical discursive psychological approach suggests that, in the context of research focusing on integration, a shift from ‘processes’ to situated ‘practices’ is useful where meaning is at stake.
Characterisation of the Novel HLA‐B*40:587 Allele by Sequencing‐Based Typing
Authors: Blandin Lucie , Visentin Jonathan , Cargou Marine , Rouzaire Paul , Lemal Richard 
Published: November 2024

ABSTRACTHLA‐B*40:587 differs from HLA‐B*40:02:01:01 by one nucleotide substitution in codon 275 in exon 5.
Six New Variants of HLA‐DPA1*01:03 Identified by Next‐Generation Sequencing
Authors: Marín Rubio Luis Alberto , Ontañón Jesús 
Published: November 2024

ABSTRACTGenomic sequence of HLA‐DPA1*01:03:01:81, ‐DPA1*01:03:01:89, ‐DPA1*01:03:01:90, ‐DPA1*01:03:01:91, ‐DPA1*01:03:01:93 and ‐DPA1*01:03:01:94 alleles in Spanish individuals.
Lucas congruences using modular forms
Authors: Beukers Frits , Tsai Wei‐Lun , Ye Dongxi 
Published: November 2024

AbstractIn this work, we prove that many Apéry‐like sequences arising from modular forms satisfy the Lucas congruences modulo any prime. As an implication, we completely affirm four conjectural Lucas congruences that were recently posed by S. Cooper and reinterpret a number of known results.