bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Ensemble-Based Conjugate Gradient Method for Reservoir Management
Authors: Zhang Y. T. , Stordal A. S. , Lorentzen R. J. , Chang Y. 
Published: April 2018

Abstract
Ensemble optimization is a rapidly emerging method for reservoir model-based production optimization. In this paper, we compared a line search method and a trust-region method to design an algorithm that retains the excellent convergence rate, but is more economical to implement when the number of variables is large. Here, the mathematics (or statistics) of ensemble-based optimization with several mathematical treatments is studied. Conjugate gradient is carried out within the general optimization framework that employs trust-region methods, aiming at delivering a faster convergence approach for reservoir management. For general benchmarks, the Rosenbrock function and five-spot waterflooding are tested for both two methods. To the best of our knowledge, the embedment of the Steihaug conjugate gradient in solving the sub-problem of ensemble-based optimization using trust-region methods is studied for the first time for reservoir management. The conjugate gradient approach is known for its prescriptive convergence theory, in which the progress can be observed at each iteration for a quadratic programming. With numerical experiments, we illustrate that trust-region method is competitive against line search method in ensemble-based production optimization.
Reservoir Management of Matured Complex Fields Based on Production Data, Standalone and Reservoir Coupled Modeling: Establishing Optimized Drainage Strategy and Lessons Learned
Authors: Tabrizy Vahid Alipour , Siddique Mohsin , Mathiassen Andreas 
Published: April 2018

Abstract
Optimizing drainage strategy is an important part of petroleum reservoir management, and has to be implemented as a dynamic process. This work describes a unique combination of standalone and coupled reservoir simulation modeling as well as production decline curve analysis and tracer data interpretation to establish optimal gas injection strategy in Smørbukk and Smørbukk Sør fields in the Norwegian Sea for improved reservoir management in terms of reserves and economy.
The drainage strategy challenge of Smørbukk and Smørbukk Sør fields is how to prioritize gas export from the fields and how to allocate the remaining gas in the efficient injectors for enhanced condensate recovery. The results triggered a change in injection strategy to rank gas disposition internally in optimized locations both in Smørbukk and Smørbukk Sør fields, and to split the injection between the two fields.
The results showed that gas-oil-ratio development of producers, gas injection efficiency (GIF), well to well tracer communication and produced water-gas ratio development are the key factors. Reservoir segments with lower produced gas-oil ratio and higher water-gas ratio development have shown the most favorable locations for gas injection. It is demonstrated also that injection efficiency decreases by time; accordingly the drainage strategy consists in two phases: Optimized gas cycling period into efficient injectors in Smørbukk and Smørbukk Sør fields and a blowdown phase including converting injectors to producers when the injection is not efficient. The work addresses the workflow and methodology for drainage strategy, main challenges and related lessons associated to reservoir simulation results, compared with production data and tracer results. The paper will shed light on the future of reservoir management and forecasting of drainage strategy for matured complex fields.
Adsorption performance of Cd(II), Cr(III), Cu(II), Ni(II), Pb(II) and Zn(II) by aminated solution-blown polyacrylonitrile micro/nanofibers
Authors: Lou Huiqing , Cao Xianzhong , Yan Xin , Wang Lina , Chen Zengbin 
Published: April 2018

AbstractIn this work, we prepared amidoxime-functionalized polyacrylonitrile (APAN) micro/nanofibers by modifying solution-blown PAN fibers with hydroxylamine hydrochloride, and investigated the adsorption performance of the APAN fibers for Cd(II), Cr(III), Cu(II), Ni(II), Pb(II) and Zn(II) from aqueous solutions. Batch experiments and quantitative analysis were conducted considering initial pH and contact time as controlling parameters. The equilibrium data were better explained by the Langmuir model with maximum adsorption capacities of 185, 204, 105, 104, 345 and 91 mg/g for Cd(II), Cr(III), Cu(II), Ni(II), Pb(II) and Zn(II), respectively. The adsorption kinetics were found to follow the pseudo-second-order kinetic model. The calculated thermodynamic parameters demonstrated that the adsorption of metal ions onto APAN fibers is feasible, spontaneous and endothermic. The five adsorption–desorption cycle experiments showed that APAN micro/nanofiber adsorbent exhibits good reusability, and has a potential application for the removal of heavy metals from wastewater.
Dihydroresveratrol Type Dihydrostilbenoids: Chemical Diversity, Chemosystematics, and Bioactivity
Authors: Vitalini Sara , Cicek Serhat S. , Granica Sebastian , Zidorn Christian 
Published: April 2018

Background:
Dihydrostilbenoids, a diverse class of natural products differing
from stilbenoids by the missing double bond in the ethylene chain linking the aromatic moieties,
have been reported from fungi, mosses, ferns, and flowering plants.

Objective:
Occurrence, structure, and bioactivity of naturally occurring dihydroresveratrol
type dihydrostilbenoids are discussed in this review.

Method:
A Reaxys database search for dihydroresveratrol derivatives with possible substitutions
on all atoms, but excluding non-natural products and compounds featuring additional
rings involving the ethyl connecting chain, was performed.

Results:
Structures include simple dihydroresveratrol derivatives, compounds substituted
with complex side chains composed of acyl moieties and sugars, and compounds containing
polycyclic cores attached to dihydrostilbenoid units. Dihydrostilbenoids have a wide spectrum
of bioactivities ranging from expectable antioxidant and anti-inflammatory activities to
interesting neuroprotective and anticancer activity. The anticancer activity in particular is
very pronounced for some plant-derived dihydrostilbenoids and makes them interesting lead
compounds for drug development. Apart from some reports on dihydroresveratrol derivatives
as phytoalexins against plant-pathogenic fungi, only very limited information is available on
the ecological role of these compounds for the organisms producing them.

Conclusion:
Dihydrostilbenoids are a class of natural products possessing significant biological
activities; their scattered but not ubiquitous occurrence throughout the kingdoms of
plants and fungi is not easily explained. We are convinced that future studies will identify
new sources of dihydrostilbenoids, and we hope that the present review will inspire such
studies and will help in directing such efforts to suitable source organisms and towards promising
bioactivities.
A UPLC-MS/MS Method for Simultaneous Determination of Six Bioactive Compounds in Rat Plasma, and its Application to Pharmacokinetic Studies of Naoshuantong Granule in Rats
Authors: Wang Ping , Jiang Shenmeng , Zhao Yu , Sun Shuo , Wen Xiaoli , Guo Xingjie , Jiang Zhen 
Published: April 2018

Background:
It is urgently needed to clarify the pharmacokinetic mechanism for the multibioactive
constituents in Traditional Chinese Medicines for its clinical applications. A rapid, sensitive
and reliable ultra-performance liquid chromatography-tandem mass spectrometry method was developed
and validated for the simultaneous determination of Danshensu, Ferulic acid, Astragaloside IV,
Naringin, Neohesperidin and Puerarin after oral administration of Naoshuantong Granule using Carbamazepine
as internal standard (IS).

Methods:
The plasma samples were pretreated by liquid-liquid extraction method using ethyl acetate
after acidification, and separated on a Waters ACQUITY UPLC® BEH C18 column (50×2.1 mm, i.d.,
1.7 µm) by gradient elution with a mobile phase composing of water (containing 0.1% formic acid) and
acetonitrile at a flow rate of 0.2 mL/min. Multiple reaction monitoring (MRM) mode with both positive
and negative ion mode was operated using an electrospray ionization (ESI) to detect the six compounds.

Result:
All calibration curves showed good linearity (r>0.99) over a wide concentration range. The
intra- and inter-day precision (RSD%) was below 8.4% and the accuracy (RE%) ranged from 91.1% to
107.5%. The extraction recoveries of the six analytes and IS in the plasma were more than 77.9% and
no severe matrix effect was observed.

Conclusion:
The fully validated method was successfully applied to the pharmacokinetics of Naoshuantong
Granule.
A Validated Chiral-RP-UPLC-MS/MS Method for the Enantiomeric Detection of Rivaroxaban In vitro
Authors: Chen Fuxin , Ma Xiaoxian , Chen Chuangqian , Li Kanshe , Chen Suying , Wen He , Gong Pin 
Published: April 2018

Background:
Rivaroxaban is the first oral, selective direct FXa inhibitor with rapid onset of
action and its biological toxicity may be related to the enantiomer.
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Objective: The aim of the current study was to develop and validate a precise, accurate, and specific
direct Chiral-RP-UPLC-MS/MS method for the enantiomeric separation and detection of rivaroxaban
and its enantiomer.

Methods:
The present study screened various conditions of chromatographic and mass spectra, including
chromatographic column model, flow velocity, phase ratio, column temperature, and collision energy,
parent/daughter ion pairs, etc. Try to match the chromatographic and mass spectrometric conditions.

Results:
Good Rs (Rs>2.5) was achieved on a Chiralpak IC column (4.6 × 250 mm, 5µm) using
H2O:acetonitrile (10:90) as mobile phase at 25 oC column temperature. The rate of flow was set at 0.4
ml/min and enantiomers were detected by triple-quadruple tandem mass spectrometry using positive
electrospray ionization (ESI) with MRM transitions of m/z 436.07>144.95. The cone voltage and collision
energy were kept at 48 V and 28 eV, respectively. The limit of detection and quantification of (S)-
rivaroxaban were 0.39 and 1.30 ng/ml, respectively. This method was validated and found to be selective,
precise, accurate, linear and robust for the quantitative determination of chiral impurities. It is also
a good application for the blood samples analysis in vitro.

Conclusion:
Chiral-RP-UPLC-MS/MS method has entirely detected (S)-rivaroxaban and its (R)- enantiomer
in very low concentration and complex matrix directly, especially for blood samples.
Muzealne zbiory w służbie misji ad gentes
Authors: Górski Jan 
Published: April 2018

The church from the beginning of its missionary work tried to substantiate it. Among other things, missionaries kept in their archives artifacts which proved the culture of peoples or nations they evangelized. Not only did they try to preserve local culture but also supported its development. The treasures of culture they collected and kept, in time proliferated and created impressive collections, the cataloguing and exhibiting of which served missionary education. The paper commences with showing the contribution of the church to the preservation of culture of evangelized nations, then it elaborates on the animation and educational role of missionary exhibitions and closes with formal and educational aims which should be accomplished by museums and missionary collections.
EFFECT OF PHYSICAL EXERCISE AND YOGA ON BLOOD PRESSURE AMONG SCHOOL CHILDREN
Authors: P Premalatha , C Kanniammal , G Valli , Mahendra Jaydeep 
Published: April 2018

Objective: The principal aim of the study is to identify the effect of physical exercise and yoga on blood pressure (BP) among children, a common cardiovascular risk factor among children in recent years. Methods: A true experimental design was adopted to find the effect of physical exercise and yoga on selected children with increased BP and weight. The weight was inferred based on the World Health Organization (WHO) chart on body mass index for age. BP and height were measured and interpreted using the WHO height percentile chart for boys/girls and BP references of National Heart, Lung, and Blood Institute, to identify hypertensive children. Hypertensive children were given physical exercise and yoga, 5 days a week, for 6 months and control group led a normal lives. Results: In the pretest, 100% of the study and control group were prehypertensive. After 3 months of physical exercise and yoga, 21% of study group became normotensive which was significant at p=0.000 and it increased to 93% after 6 months with the significance of p=0.000. The weight and systolic BP (SBP) had a significant positive correlation. The age (p=0.001), number of family members, type of family (p=0.01), mother’s occupation, family history of obesity, and chronic illness among fathers (p=0.05) had a significant association with SBP of the children. Conclusion: The study concluded that physical exercise and yoga reduced childhood hypertension as well as is a cost effective and easily practicable intervention for children to minimize cardiovascular risk during their adulthood.
COMBINED USE OF ACTIVE AND PASSIVE SURFACE WAVES FOR SHALLOW SUBSURFACE INVESTIGATION IN NOISY URBAN AREA OF SÃO PAULO CITY, BRAZIL
Authors: Eikmeier Claus Naves , Prado Renato Luiz , Taioli Fabio 
Published: April 2018

ABSTRACT. The dynamic shear modulus (Gdin) is important for geotechnical engineering, particularly for calculating the dynamic response of foundations. Gdin is determined from material densities and S-wave propagation velocity (VS). Usually, crosshole test is used for such determination. However, it is an expensive and invasive technique because it is based on drilling. The MASW method (Multichannel Analysis of Surface Waves) becomes an interesting option for being faster, more economical and easier to carry out. This paper presents results obtained with MASW method in a densely built up area with high traffic noise level in São Paulo city, Brazil. Results are compared with those obtained by crosshole test as well as geotechnical sounding data. The influence of some acquisition parameters was evaluated in data quality and final inversion result. Besides, it was also tested the passive mode test that is recording ambient noise. Best results were obtained by joint inversion of fundamental and higher curve modes extracted from stacked images generated from data acquired employing sledgehammer and passive sources. Final VS models were coherent with results obtained from crosshole seismic testing and mechanical sounding description, demonstrating MASWmethod can generate important information for geological and geotechnical investigation of urban areas. Keywords: MASW, seismic, Rayleigh wave, velocity profile, dispersion curve.RESUMO. O módulo de cisalhamento dinâmico (Gdin) é importante para a engenharia geotécnica, particularmente nos cálculos de fundações sujeitas a esforços dinâmicos. O Gdin é determinado a partir das densidades dos materiais e das velocidades de propagação das ondas S (VS). Normalmente se utiliza o ensaio crosshole, ensaio sísmico entre poços, para tal determinação, porém, trata-se de uma aquisição de execução dispendiosa. Este trabalho apresenta resultados obtidos com o método MASW em uma área densamente edificada e com alto nível de ruído de tráfego na cidade de São Paulo, Brasil, que são comparados com os obtidos por ensaio crosshole, assim como com dados de sondagem direta. Avaliou-se, também, a influência de alguns parâmetros de aquisição na qualidade do dado e no resultado final da inversão. Testou-se ainda a aquisição de dados no modo passivo, ou seja, registrando-se o ruído ambiental. Os melhores resultados foram obtidos utilizando-se inversão conjunta dos modos fundamental e superiores das curvas extraídas do empilhamento das imagens de dispersão dos dados gerados com as fontes marreta e passiva. Os modelos de VS obtidos foram coerentes com os resultados obtidos do ensaio sísmico crosshole e da descrição da sondagem mecânica, demonstrando que o método MASW pode gerar importantes informações para investigações geológicas e geotécnicas de áreas urbanas. Palavras-chave: MASW, sísmica, onda Rayleigh, perfil de velocidades, curva de dispersão.
Appetite, Glycemia, and Entero-Insular Hormone Responses Differ Between Oral, Gastric-Remnant, and Duodenal Administration of a Mixed-Meal Test After Roux-en-Y Gastric Bypass
Authors: Gero Daniel , Steinert Robert E. , Hosa Hanna , Cummings David E. , Bueter Marco 
Published: April 2018

OBJECTIVE
To examine the effect of different feeding routes on appetite and metabolic responses after Roux-en-Y gastric bypass (RYGB).

RESEARCH DESIGN AND METHODS
A standard liquid meal was administered either orally, into the gastric remnant, or intraduodenally 6 months after RYGB. Changes in plasma glucose, insulin, glucagon-like peptide 1 (GLP-1), glucose-dependent insulinotropic peptide (GIP), peptide YY (PYY), and appetite were measured pre- and postprandially.

RESULTS
Postprandial GLP-1 and PYY responses were similar, whereas glucose, insulin, and GIP levels differed markedly after oral versus intraduodenal feeding. Intraduodenal feeding prompted an intermediate appetite response (i.e., between oral and intragastric). For postprandial glucose, insulin, and GIP levels, the intraduodenal route was more similar to the intragastric than the oral route. Intragastric administration did not evoke changes in appetite, glucose, or insulin; however, it slightly increased GLP-1 and PYY and moderately increased GIP.

CONCLUSIONS
Appetite and metabolic responses after RYGB depend on the route by which nutrients enter the gastrointestinal tract.
O espaço-tempo escolar como elemento curricular
Authors: Peçanha Valéria , De Souza Luiz 
Published: April 2018

Resenha da obra: VIÑAO FRAGO, Antonio; ESCOLANO, Agustín. Currículo, espaço e subjetividade: a arquitetura como programa . Tradução: Alfredo Veiga-Neto. 2. ed. Rio de Janeiro: DP&A, 2001. 152 p.
Acesso e democratização do ensino superior com a Lei nº 12.711/12: O câmpus de Londrina da Universidade Tecnológica Federal do Paraná (UTFPR)
Authors: Guerrini Daniel , Piconi Larissa Bassi , Sturion Leonardo , Da Mata Ednei Aparecido Dias 
Published: April 2018

Este artigo analisa o ingresso de estudantes nos cursos da Universidade Tecnológica Federal do Paraná, Câmpus Londrina, no ano de 2015, com base nas mudanças implementadas pela Lei de Cotas (Lei Federal nº 12.711/2012). Essa lei tornou obrigatória a reserva de vagas para alunos egressos de escolas públicas, de baixa renda e autodeclarados pretos, pardos ou indígenas (PPI) nas instituições federais de ensino superior e técnico, constituindo-se como medida compensatória diante dos efeitos dos privilégios sociais e da desigualdade nas condições de acesso ao ensino superior. Investiga o preenchimento das vagas reservadas na instituição mencionada para identificar em que medida as ações afirmativas têm cumprido os propósitos para os quais foram pensadas. Foram coletadas as notas de entrada dos alunos em 2015, buscando suas medidas de centralidade estatística, comparando cotistas com não cotistas e os diferentes cursos entre si. Analisa, ainda, a relação entre reserva de vaga e seu preenchimento nas quatro categorias de cotistas e no grupo de não cotistas. Observa-se que o prestígio dos cursos é um fator relevante para o aumento das medianas das notas de entrada dos estudantes e também que a categoria de cotas para pessoas de baixa renda tem colocado entraves para o preenchimento de suas vagas.
Depression and anxiety in axial spondyloarthritis
Authors: Chan Cynthia Yan-yan 
Published: April 2018

Abstract
Axial spondyloarthritis (SpA) is a spectrum of chronic inflammatory rheumatologic diseases commonly presenting with symptoms of inflammatory back pain, peripheral joint pain, and fatigue. When compared to the general population, patients with SpA have higher prevalence of depression and anxiety symptoms. Poor psychological status is associated with worse disease activity, poorer functional status, poor treatment adherence, and unhealthy lifestyle choices such as cigarette smoking. The Chinese-bilingual Hospital Anxiety and Depression Scale (HADS) is a validated tool to screen depression and anxiety in patients with axial SpA. The cytokine theory of depression may explain emerging evidence on the mutually beneficial effects of antidepressants on disease outcomes and anti-tumor necrosis factor α (TNFα) therapy on psychological status.
Minat Siswa Dalam Kurikulum Muatan Lokal
Authors: -- Sumiyati 
Published: April 2018

This research is a survey research, which aim to know what is the relationship between motivation and lerning condition with learning interest of student local content at junior high school in West Jakarta. There are three research hypothesis, first is there is a positive relation between motivation with learning interest of student local content, second is there is a positive relation between learning condition with learning interest of student local content, and third is there is a positive relation between motivation and learning condition with learning interest of student local content. This subject research is student of junior high school in West Jakarta enlisted in the year lesson 2009/2010 with the sample amount 55 people. Technique of data collecting performed is use questionnaire. Based of the result analysis data and solution obtained that Fhit is more than Ftable or 4,66 more than 3,18. It means that there is a positive relation between motivation and learning condition with learning interest of student local content.Â ABSTRAKÂ Penelitian survei ini bertujuan untuk mengetahui apakah terdapat hubungan antara motivasi dan kondisi belajar dengan minat belajar muatan lokal siswa SMP di Jakarta Timur. Hipotesis penelitian ini ada tiga yaitu, pertama terdapat hubungan positif antara motivasi dengan minat belajar muatan lokal siswa, kedua terdapat hubungan positif antara kondisi belajar dengan minat belajar muatan lokal siswa, dan ketiga terdapat hubungan positif antara motivasi dan kondisi belajar dengan minat belajar muatan lokal siswa. Subjek penelitian ini adalah siswa SMP di Jakarta Timur yang terdaftar dalam tahun ajaran 2009/2010, dengan jumlah sampel 55 orang. Teknik pengumpulan data yang dilakukan adalah dengan menggunakan angket. Dari hasil analisis data dan pembahasan diperoleh bahwa F hitung > dari F tabel atau 4,66 lebih besar dari 3,18 artinya terdapat hubungan positif antara motivasi belajar dan kondisi belajar dengan minat belajar muatan lokal siswa.Â