bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal Dynamics of Inhalation-Linked Activity across Defined Subpopulations of Mouse Olfactory Bulb Neurons ImagedIn Vivo
Authors: Short Shaina M. , Wachowiak Matt 
Published: June 2019

AbstractIn mammalian olfaction, inhalation drives the temporal patterning of neural activity that underlies early olfactory processing. It remains poorly understood how the neural circuits that process incoming olfactory information are engaged in the context of inhalation-linked dynamics. Here, we used artificial inhalation and two-photon calcium imaging to compare the dynamics of activity evoked by odorant inhalation across major cell types of the mouse olfactory bulb (OB). We expressed GCaMP6f or jRGECO1a in mitral and tufted cell (MTC) subpopulations, olfactory sensory neurons (OSNs), and two major juxtaglomerular interneuron classes and imaged responses to a single inhalation of odorant. Activity in all cell types was strongly linked to inhalation, and all cell types showed some variance in the latency, rise times, and durations of their inhalation-linked response. Juxtaglomerular interneuron dynamics closely matched that of sensory inputs, while MTCs showed the highest diversity in responses, with a range of latencies and durations that could not be accounted for by heterogeneity in sensory input dynamics. Diversity was apparent even among “sister” tufted cells innervating the same glomerulus. Surprisingly, inhalation-linked responses of MTCs were highly overlapping and could not be distinguished on the basis of their inhalation-linked dynamics, with the exception of a subpopulation of superficial tufted cells expressing cholecystokinin (CCK). Our results are consistent with a model in which diversity in inhalation-linked patterning of OB output arises first at the level of sensory input and is enhanced by feedforward inhibition from juxtaglomerular interneurons which differentially impact different subpopulations of OB output neurons.
Implementing Evidence-Based Strategies to Improve HPV Vaccine Delivery
Authors: Gilkey Melissa B. , Parks Michael J. , Margolis Marjorie A. , McRee Annie-Laurie , Terk Jason V. 
Published: June 2019

BACKGROUND:
High-quality evidence indicates that intervening with health care providers improves human papillomavirus (HPV) vaccine delivery. However, scaling up evidence-based strategies in real-world clinical practice remains challenging. We sought to improve the reach and impact of strategies for HPV vaccination quality improvement (QI) through local adaptation and implementation in a large, not-for-profit health care system.

METHODS:
We conducted an HPV vaccination QI program using existing materials to support physician training coupled with assessment and feedback. Local physicians with high HPV vaccination rates facilitated training, which included didactic instruction and video vignettes modeling effective communication. We randomly assigned 25 clinics with 77 physicians to the QI arm or the wait-list control arm. We used hierarchical linear models to assess HPV vaccination coverage (≥1 dose) over 6 months among patients aged 12 to 14.

RESULTS:
Of 45 physicians in the QI arm, the program reached 43 (95%) with training plus assessment and feedback. In the overall sample, HPV vaccination coverage increased in both the QI and control arms (8.6 vs 6.4 percentage points, respectively), although the 2.2–percentage point difference did not reach statistical significance. Sensitivity analyses that excluded physicians with poor data quality indicated a statistically significant advantage of 3.3 percentage points for QI versus control (b = 0.034; SE = 0.015; P &lt; .05).

CONCLUSIONS:
Our locally adapted QI program achieved excellent reach, with small improvements in HPV vaccination coverage. Future implementation research is needed to bolster program impact and support health systems in leveraging local resources to conduct these programs efficiently.
Posguerra y posverdad: La condición masónica de Margarita Nelken
Authors: Jardón Pardo de Santayana Pelayo 
Published: June 2019

Tras la Guerra Civil española, la diputada Margarita Nelken (1893-1968) fue juzgada por el Tribunal para la Represión de la Masonería y el Comunismo. Fue acusada de los delitos de masonería y comunismo y procesada en rebeldía. La principal prueba física del sumario era una carta de recomendación de la logia Lealtad, de Barcelona, fechada en 1924, que en realidad correspondía a la cupletista Stella Margarita. Pese a la falta de pruebas, se consideró en la sentencia que Margarita Nelken había ingresado en la masonería, a la que había dispensado “protección importante”.
<i>Seminario Permanente Internacional de Historia de las Masonerías</i> (Gijón, Principado de Asturias, España, 22-25 de febrero de 2019)
Authors: García Robles Marco Antonio 
Published: June 2019

Crónica del Seminario Permanente Internacional de Historia de las Masonerías, realizado en Gijón, Principado de Asturias, España, del 22 al 25 de febrero de 2019.
Study of Plans Sustainability of Active Moving Objects Control Systems Application
Authors: Sugak Vladimir , Volkov Valery , Salukhov Vladimir , Karaychev Aleksey 
Published: June 2019

The paper considers research of the sustainability plans of active moving objects (AMOs) control system application. AMOs are material objects moving in space and carrying out informational, material and energetic interaction with objects, control points and other AMOs.
Use of AMOs is usually regulated by strict requirements, so any time delay or incomplete achievement of target effect are unacceptable. The reason of failing to perform a purpose task can be the development of control using incorrect plans, so that realization of the plan is unstable due to random factors or targeted effects of the environment and other systems. The paper deals with problematic issues of complex research of active moving objects control application stability plans .
Quantitative and qualitative assessment methods of stability plans , ways and means of ensuring required levels of stability are proposed by the authors. In this case planning task is considered dynamic, which provides plan correction by means of organizational, structural and program-algorithmic measures to ensure stability. The most adequate model of plan implementation is appropriate system of differential equations. Notion of stability probability is defined to account stochastic character of disturbance effect . The expression for stability criterion is obtained. It allows to establish the fact of sustainability and unsustainability based on analysis of properties of a purposefully built Lyapunov function and disturbances characteristics.
“You can’t go back to holding hands.” Reading Judy Blume’s Forever in the #MeToo Era
Authors: Spiering Jenna , Kedley Kate 
Published: June 2019

Judy Blume’s Forever is a cultural artifact that gives readers a historical look at society’s attitudes about sex and sexuality at the time of publication in 1975. However, in the #MeToo era, Blume’s text is poised for new analysis in light of important conversations and concerns about sex, sexuality, and consent. In this article, Critical Youth Studies and Queer Theory are used to explore the ways in which young readers can critically engage with Blume’s novel and questions about virginity, sex, sexuality, and consent associated with the #MeToo movement.
Features of cardiovascular remodeling, the level of neurohumoral factors depending on the degree of chronic heart failure and kidney dysfunction
Authors: Kamilova U. K. , Rasulova Z. D. , Zakirova G. A. , Toshev B. B. 
Published: June 2019

Aim. To study the relationship between the level of the N-terminal prohormone of brain natriuretic peptide (NTproBNP) and aldosterone in serum, cardiovascular remodeling parameters with the degree of chronic heart failure (CHF) and kidney dysfunction (KD).Material and methods. Fifty two patients with coronary artery disease with CHF of I (19 patients), II (21) and III (12) functional classes (FC) were examined. All patients underwent echocardiography with assessment of systolic function and structural-geometric parameters of the left ventricle (LV), blood flow study at the level of the common carotid artery (CCA) with the determination of the thickness of the intim-media complex, velocity parameters of blood flow, resistance (RI) and pulsation (PI) indexes, estimated glomerular filtration rate (eGFR) by CKD-ЕРI method, the level of NTproBNP and aldosterone in serum. The patients were divided depending on the eGFR elvel: 30< eGFR ≤60 ml/min/1,73 m2 — 14 patients, eGFR >60 ml/min/1,73 m2 — 38 patients.Results. Patients with II FC CHF had the medium-high NTproBNP and aldosterone values. Subjects with FC III CHF had high levels of NTproBNP and aldosterone. A correlation relationship was found between the NTproBNP, aldosterone and ejection fraction (EF) levels (r=-0,70 and r=-0,72, respectively), between the NTproBNP, aldosterone and enddiastolic LV velocity (r=0,78 and r=0,70, respectively). There was a significant thickening of the carotid intima-media complex and a decrease in the blood flow velocity and an increase in vascular resistance with increasing CHF. We also noted a significant difference in the maximum end-diastolic velocity in patients with eGFR ≤60 ml/min/1,73 m2 compared with this indicator in patients with eGFR >60 ml/min/1,73 m2.Conclusion. In patients with CHF, a significant increase in NTproBNP and aldosterone levels is associated with FC of CHF, LV systolic dysfunction and KD. The interrelation of cardiovascular remodeling indicators with the degree of CHF and KD was revealed.
PENINGKATAN KEMAMPUAN KOGNITIF ANAK MELALUI PENERAPAN METODE EKSPERIMEN DALAM PEMBELAJARAN SAINS PADA ANAK
Authors: Fidiyani Intan Martha , Nugraha Ali , Maryana Rita 
Published: June 2019

Abstrak : Peningkatan Kemampuan Kognitif Anak Melalui Penerapan Metod Eksperimen dalam Pembelajaran Sains pada Anak. Tujuan dari penelitian ini e Abstrak : Peningkatan Kemampuan Kognitif Anak Melalui Penerapan Metod adalah melaksanakan pembelajaran dengan menggunakan metode eksperimen/percobaan untuk meningkatkan kemampuan kognitif anak di TK. Kartini Desa Jatitengah Kecamatan Jatitujuh Kabupaten Majalengka. Jenis penelitian yang digunakan yaitu Peneletian Tindakan Kelas (PTK) yang mencakup aspek penilaian pengembangan kognitif yaitu 1). Mengenal dan Mencampur Warna, 2). Mengenal Sebab Akibat Terjadinya Hujan, 3). Mengenal Perbedaan Kasar dan Halus, 4). Meniru Pola, 5). Menyusun Kepingan Puzzle. Adapun subjek penelitian adalah anak kelompok B TK. Kartini Desa Jatitengah Kecamatan Jatitujuh Kabupaten Majalengka tahun pelajaran 2014-2015 yang berjumlah 39 anak. Berdasarkan hasil observasi bahwa penerapan metode eksperimen/percobaan untuk meningkatkan kemampuan kognitif anak menunjukan perkembangan yang sangat baik. Hal ini terlihat dari peningkatan setiap siklusnya, diantaranya siklus I 18,97% anak Belum Berkembang (BB), 72,82 anak Mulai Berkembang (MB), 8,20% anak Berkembang Sesuai Harapan, dan 0% anak Berkembang Sangat Baik (BSB). nilai rata-ratanya diperoleh sebesar 1,9 dan ketuntasan belajarnya mencapai 47,24%. Pada siklus II mengalami peningkatan diantaranya 1,54% anak yang Belum Berkembang (BB), 41,74% anak Mulai Berkembang (MB), 41,54% anak Berkembang Sesuai Harapan (BSH), 11,28% anak Berkembang Sangat Baik (BSB) nilai rata-ratanya diperoleh sebesar 2,56 dan ketuntasan belajarnya mencapai 64,49% dan pada siklus III yaitu mengalami peningkatan yang sangat mengembirakan yaitu 0% anak Belum Berkembang (BB), 0,51% anak mulai Berkembang (MB), 46,67% anak Berkembang Sesuai Harapan (BSH) dan 52,82% anak yang Berkembang Sangat Baik (BSB) nilai rata-ratanya diperoleh sebesar 3,5 dan ketuntasan belajarnya mencapai 87,44%. Berdasarkan hasil penelitian dapat disimpulkan bahwa penerapan metode eksperimen dapat meningkatkan kemampuan kognitif anak. Rekomendasi dari penelitian ini adalah guru dapat menggunakan metode eksperimen dalam kegiatan pembelajaran di TK.
MENINGKATKAN KEMAMPUAN MOTORIK HALUS ANAK MELALUI PERMAINAN LEGO BLOCK
Authors: Mutiara Sarah Nandya 
Published: June 2019

Abstract : Improving Children’s Fine Motor Skills Through Lego Block Games. The research was conducted based on the problems found among children of Early Childhood Education (Indonesian, and henceforth, PAUD) Post Miana V, namely the low fine motor skills, especially in creating objects according to various media, creating two forms from blocks, and building a tower of a minimum of 8 (eight) cubes. In response to these problems, improvements in instruction are required. In this research, the researcher designed Lego block games to improve group A students’ fine motor skills. The research aims to find about the profile of children’s fine motor skills before the implementation of Lego block games, the implementation of Lego block games, and the improvement of group A students’ fine motor skills after the implementation of Lego block games in PAUD Post Miana V. It adopted classroom action research method. The subjects were 8 (eight) children of group A PAUD Post Miana V. The findings show that after the implementation of Lego block games, there were significant improvements in the fine motor skills of group A students of PAUD Post Miana V. The improvements were most observable in the increasing number of children who reached the stages of beginning to develop and developing according to expectation. Based on these results, Lego block games can be used as an effective learning method to improve kindergarten children’s fine motor skills.Abstrak : Meningkatkan Kemampuan Motorik Halus Anak Melalui Permainan Lego Block. Penelitian ini di lakukan atas dasar permasalahan yang muncul pada anak Pos PAUD Miana V yaitu rendahnya kemampuan motorik halus anak, menciptakan sesuai dengan berbagai media, mencipta 2 bentuk dari balok, menyusun menara kubus minimal 8. Tindak lanjut dari permasalahan tersebut perlu adanya perbaikan pembelajaran. Peneliti merancang penelitian melalui permainan lego block untuk meningkatkan kemampuan motorik halus anak kelompok A. Tujuan dari penelitian ini untuk mengetahui profil kemampuan motorik halus anak sebelum diterapkan permainan lego block, mengetahui bagaimana penerapan permainan lego block, dan mengetahui peningkatan kemampuan motorik halus anak kelompok A sesudah diterapkan permainan lego block di Pos PAUD Miana V. Metode penelitian yang di gunakan adalah Penelitian Tindakan Kelas (PTK). Subjek pada penelitian ini adalah anak kelompok A Pos PAUD Mianan V berjumlah 8 anak. Kondisi akhir kemampuan motorik halus menunjukan terdapat peningkatan yang signifikan terhadap kemampuan motorik halus anak kelompok A Pos PAUD Mianan V setelah diterapkan permainan lego block. Peningkatan kemampuan terlihat dari semakin banyaknya anak yang sudah mencapai tahap mulai berkembang (MB) dan berkembang sesuai harapan (BSH). Berdasarkan hasil penelitian permainan lego block dapat di gunakan sebagai metode pembelajaran yang efektif untuk meningkatkan kemampuan motorik halus anak TK.
HUBUNGAN ANTARA PENATAAN LINGKUNGAN BELAJAR OUTDOOR DENGAN KEMAMPUAN MOTORIK KASAR ANAK USIA DINI
Authors: Rosnita Astiani , Rudiyanto Rudiyanto , Mariyana Rita 
Published: June 2019

The Contribution Of Outdoor Learning Environment To Young Children’s Gross Motor Skills. The research aims to determine about contribution of outdoor learning enviroment to young children’s evaluated gross motor skills. The research conducted in kindergartents at Gunung Sindur District Bogor Regency. It adopted corelation methode. The subject of the research with 80 young children from 8 (eight) kindergratens Group B that are taken from at Gunung Sindur they are TK Islam Ar Rasyid,TK Pertiwi,TK Al Kautsar,TK Tunas Bangsa,TK Tunas Karya,TK Nurl Iman,TK An Nahl,and TK An Nur. Data were collected through observation of outdoor learning environment and from the existing data in each respective school containing information about children’s gross motor skills. The data were analyzed with quantitative-descriptive technique involving several stages, namely validation, reliability check, the comparison of mean test, inference. The findings show that the outdoor learning environment was in the “ideal” category for 62,50% and the result of young children’s gross motor skills evaluation were in category “develop according to expectations” for 48,75%. therefor, it can be inferred that the setting of outdoor learning environment has contribution to young children’s gross motor skills.Hubungan Antara Penataan Lingkungan Belajar Outdoor Dengan Kemampuan Motorik Kasar Anak Usia Dini. Penelitian ini bertujuan untuk mengetahui hubungan antara penataan lingkungan belajar outdoor dengan kemampuan motorik kasar anak usia dini. Penelitian ini dilakukan di sekolah Taman Kanak-kanak se-Kecamatan Gunung Sindur Kabupaten Bogor. Penelitian ini menggunakan metode korelasi. Subjek penelitian berjumlah 80 orang anak kelompok B dari 8 sekolah Taman Kanak-kanak, Taman Kanak-kanak yang di teliti yaitu TK Islam Ar-Rasyid, TK Pertiwi, TK Al-Kautsar, TK Tunas Bangsa, Tunas Karya, Nurul Iman, TK An-Nahl dan TK An-Nur. Teknik pengumpulan data dalam penelitian ini yaitu melalui observasi mengenai lingkungan belajar outdoor dan pengambilan data yang sudah ada di setiap sekolah yang berisi kemampuan motorik kasar anak. Teknis analisis data yang digunakan adalah analisis data deskriptif kuantitatif dengan beberapa tahapan diantaranya adalah proses validasi, reliabilitas, analisis uji perbandingan rata-rata, dan penarikan kesimpulan. Hasil penelitian menunjukkan lingkungan belajar outdoor berada dalam ketegori ideal yaitu sebesar 62,50% dan kemampuan motorik kasar anak usia dini berada dalam kategori berkembang sesuai harapan (BSH) sebesar 48,75%. Sehingga dapat ditarik kesimpulan adanya hubungan penataan lingkungan belajar outdoor dengan kemampuan motorik kasar anak usia dini.
Du français, dlalang et des poèmes incorrects : langage et poétique chez Katalin Molnár
Authors: Bourassa Lucie 
Published: June 2019

Le présent article aborde le rapport entre théorie du langage et poétique dans les « entours » — articles, manifestes, entrevues, préfaces et notes — de l’œuvre de Katalin Molnár, poète française d’origine hongroise. Depuis Mallarmé, nombreux sont les poètes français qui ont déploré les « défauts des langues », assignant à la poésie la tâche de les pallier. Si Molnár reprend certaines doléances de ses prédécesseurs, par exemple sur l’arbitraire linguistique et sur le rapport entre communication et pouvoir, sa théorie se démarque à maints égards des leurs. Et les solutions poétiques qu’elle propose manifestent un déplacement par rapport à la tradition : elle cherche moins à remédier aux défauts de la langue qu’à les exhiber, à jouer avec les manques, les stéréotypies, les pauvretés de la parole.AbstractThis article approaches the Relationship between language theory and poetics in the margins (articles, manifestos, interviews, prefaces and footnotes) of Katalin Molnár’s work. Since the end of 19th century, many poets, following Mallarmé, have complained about imperfections of languages, and assigned to poetry the aim of compensating for their defaults. Molnár, a French writer born and educated in Hungary, take up some of her predecessors’ complaints: she laments, for instance, the arbitrary character of language and the relationship between communication and power. But her theory shows also many differences from theirs. And the poetic “solutions” she puts forward bring something new in this tradition: she doesn’t try so much to remedy language imperfections as to expose them and to play with the deficiencies, the stereotypes, the poverties of speech.
The Role of Feminist Standpoint and Intersectionality Epistemologies in Providing Insights into the Causes of Gender Disparity in Higher Education
Authors: Norgbey Enyonam Brigitte 
Published: June 2019

Higher education plays a critical role in society’s development, particularly in the current era of globalization in which knowledge-based innovations are critical for development. However, women’s underrepresentation in higher education remains a persistent issue of concern, particularly, in sub-Saharan Africa. The gender gap in higher education is created by complex interconnected sets of deep-rooted factors. A clear understanding of the underlying causes of gender inequality in higher education is necessary to develop effective interventions to overcome this disparity. Feminist standpoint and feminist intersectionality epistemologies have been used to provide insights into gender disparities in higher education. Drawing on existing published literature, I will discuss the conceptual and theoretical frameworks of these two feminist epistemologies and explore the methodological implications of these epistemologies for critically examining gender disparities in higher education in the context of sub-Saharan Africa.
Keywords: epistemology, feminism, gender, higher education, intersectionality
Inleiding: Johannes Hudde (1628–1704), ‘groot ende onvergelykelyk wiskunstenaar’
Authors: Jorink Eric , Zuidervaart Huib 
Published: June 2019

In this introduction to this special issue of Studium devoted to Johannes Hudde, member of an Amster- dam family of patricians, it is argued that most of Hudde’s achievements in mathematics, optics, medi- cine and philosophy were related to a Cartesian research program that became fashionable in Dutch Republic the 1650s and 1660s. Hudde foremost owes his ‘claim to fame’ to his mathematical discover- ies, as published in the Latin translation and elaboration by Leiden Professor Van Schooten Junior of Descartes’ new geometry. However, Hudde is also known as the inventor of the single lens microscope and was also active as an author in the controversy on the Copernic system, which played central role in Descartes’ Natural Philosophy. In 1666 Hudde was also one of Spinoza’s correspondents, asking Spi- noza’s about the nature of the Creator, and sharing his knowledge about the construction of telescope lenses. After having become a regent in 1667, Hudde used his scientific skills in several advisory roles, for instance as an Amsterdam Mayor and a Director of the Dutch East India Company. In that capacity he also became a patron of the arts and the sciences.
Hudde en Spinoza: waarom er maar één God is
Authors: Van Bunge Wiep 
Published: June 2019

In 1666 Johannes Hudde had a brief but important epistolary exchange with the philosopher Spinoza. Hudde had probably been triggered by Spinoza’s demonstration of God’s uniqueness, delivered in his introduction to Cartesianism of 1663. Hudde turned out to be a tenacious correspondent, not easily satisfied and he inspired Spinoza to elucidate his own metaphysics which at the time had not been pub- lished yet. Meanwhile, Spinoza had to be careful: he was fully aware of the heterodox nature of his own metaphysics, according to which for instance extension is one of God’s attributes. Hudde on the other hand deserves credit for identifying a major puzzle in Spinoza’s metaphysics, for if God’s attributes are indeed as autonomous as Spinoza wants them to be, how are they able to constitute a single God?