bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying and Managing Drug Induced Parkinsonism: The Role of Neuroscience Nurses
Authors: Nichols Linda , Alty Jane 
Published: December 2024

Abstract
Drug induced parkinsonism (DIP) is one of the most frequently occurring side effects of dopamine-receptor blocking agents such as antipsychotic (neuroleptic) and antiemetic drugs. It typically presents with extrapyramidal signs, such as slowed movements, reduced facial expression and muscle stiffness. In contrast to Parkinson’s disease, which is caused by a progressive degeneration of pre-synaptic dopaminergic neurons that project from the substantia nigra in the brainstem, DIP is thought to usually occur due to the post-synaptic antagonism of dopamine receptors in the striatum. However, the two conditions can sometimes be clinically indistinguishable, and may even occur together, and thus it can be challenging to make an accurate diagnosis of DIP. It is important to consider DIP in the differential diagnosis of any person with extrapyramidal signs within the context of recent medication changes as the condition is reversible when the offending drug is withdrawn and, without early identification, there is substantial risk of increased morbidity, complications such as falls, and poor quality of life. Recent advancements in cerebral imaging have improved diagnostic accuracy but this technology is costly and not widely available.
There is a dearth of literature pertaining to the role of neuroscience nurses and DIP. This is concerning as the potential for DIP presentations to occur within the neuroscience setting is high. Neuroscience nurses, particularly those working within the movement disorder speciality areas, need the skills to advocate and pursue further investigation for patients who present with extrapyramidal signs, especially if these begin in the context of the prescription of dopamine-blocking drugs. This review is written primarily for neurosciences nurses but will be applicable to a wide range of healthcare workers; it aims to outline potential causative drugs, risk factors and the key clinical characteristics of DIP. It also highlights useful features that help distinguish DIP from Parkinson’s disease, summarises investigations and discusses management and care.
Surgical Orthodontic Treatment of Class III Malocclusion with Unilateral Open Bite Due to Impacted Premolar with Dilacerated Root: A Case Report
Authors: Kashio Haruna , Yamaguchi Masaru , Yamazaki Astue , Minamida Yasuhito , Shimo Tsuyoshi , Mizoguchi Itaru , Iijima Masahiro 
Published: December 2024

Background
Dilacerated teeth may interfere with eruption and movement, making orthodontic treatment difficult.

Case Report
This case report describes successful surgical orthodontic approaches for a 14-year-old girl with skeletal Class III malocclusion, a unilateral open bite caused by a severely dilacerated mandibular left first premolar, and severe crowding in the mandibular dentition. The patient underwent surgical subluxation of the dilacerated premolar, followed by a combination of non-extraction orthodontic therapy and orthognathic surgery.
A left lateral open bite caused by a severely dilated mandibular left first premolar was corrected through tooth traction after subluxation for root apical transection. Class I molar relationships and improved facial profiles were achieved with maxillary advancement, adjunctive counterclockwise mandibular rotation, and genioplasty.

Conclusion
This case report suggests using subluxation in severely dilacerated teeth to enable orthodontic tooth movement with high stability, thereby expanding the possibility of non-extraction treatment.
The Missing Link: Academic Motivation as a Mediator in the Relationship between Mindfulness and Critical Thinking Skills in Indonesian First-Year Undergraduates
Authors: Agoes Salim Rose Mini , Felicia Margareth Sondang , Setiamurti Astri 
Published: December 2024

Background
Critical thinking is essential for university students to deal with academic demands. Preliminary research indicates that first-year undergraduate students in Indonesia have low critical thinking skills, highlighting the importance of developing these skills early to better adapt to university life.

Objective
This research examined the role of academic motivation as a mediator between mindfulness and critical thinking skills among first-year undergraduate students in Indonesia.

Methods
Data were collected through e-flyers and questionnaires distributed via social media, using convenience and snowball sampling techniques. The sample included 186 first-year students (aged 18–23, M = 18.9) from the class of 2022. Critical thinking was assessed with the Analog Test, mindfulness was measured using the 15-item Five Facet Mindfulness Questionnaire (FFMQ-15), and academic motivation was evaluated with the Indonesian Short Version of the Academic Motivation Scale. Pearson correlation and regression analyses were performed.

Results
The study found a statistically significant indirect effect of mindfulness on critical thinking, mediated by intrinsic academic motivation (β = 0.010, p = 0.027, 95% CI = 0.00065–0.023). While this mediation effect was significant, the effect size was small, suggesting that while mindfulness influenced critical thinking through intrinsic motivation, its practical significance was limited.

Conclusion
This study highlights that mindfulness predicts critical thinking primarily through intrinsic academic motivation, with no significant direct effect. The small effect size suggests that other factors may also influence this relationship. Further research is needed to identify additional mediators or contextual variables.
The Therapeutic Potential of Targeting the Pd-L1/Pd-1 Immune Checkpoint Pathway in Alzheimer's Disease
Authors: Mehrabadi Shima 
Published: December 2024

Abstract:
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
the accumulation of amyloid-β plaques, neurofibrillary tangles, and chronic neuroinflammation.
Emerging evidence suggests that the PD-L1/PD-1 immune checkpoint pathway plays a critical
role in modulating neuroinflammation, microglial function, and amyloid-β clearance in AD. This
review summarizes the current understanding of the PD-L1/PD-1 pathway in AD and discusses its
potential as a therapeutic target. Preclinical studies and clinical trials have demonstrated that targeting
the PD-L1/PD-1 axis can enhance microglial phagocytosis, promote amyloid-β clearance,
and reduce neuroinflammation. We examine the potential benefits and challenges of using existing
immunotherapy drugs, such as anti-PD-L1 and anti-PD-1 antibodies, in the context of AD.
Additionally, we explore the development of novel, more specific agents targeting the PDL1/
PD-1 pathway, as well as potential synergistic approaches with other immunomodulatory or
amyloid-β-targeting treatments. This review provides a comprehensive and up-to-date analysis of
the PD-L1/PD-1 immune checkpoint pathway's role in Alzheimer's disease, highlighting its
promising therapeutic potential for improving patient outcomes. Further research is warranted to
optimize treatment strategies and evaluate the long-term safety and efficacy of targeting this axis
in clinical settings.
Mistakes and misunderstandings in pre-travel consultations – common areas of confusion
Authors: Bunce Alys 
Published: December 2024

Travel health can be a huge topic to know a lot of things about, whilst trying to navigate many other subjects at the same time. Written by an experienced trainer in the field of travel health, this article explores some of the common misunderstandings that often come up during courses during travel health consultations in the UK.
THE IMPACT OF VIRTUAL TEAM DYNAMICS ON ORGANIZATIONAL PERFORMANCE IN SHARIA WITH REMOTE WORK OPTIMIZATION STRATEGIES AS MEDIATION AT BANK MUAMALAT, PADANG
Authors: Sarianti Kiki , Rosalina Desi , Desti Yolanda , Damayanti Nora , Ramadhi Ramadhi , Amri Andi , Azhari Alim Bahri 
Published: December 2024

This study aims to analyze the impact of virtual team dynamics on organizational performance in sharia, with a remote work optimization strategy as a mediating variable at Bank Muamalat Padang City. This study uses a quantitative approach by collecting data through a survey of employees who work in virtual teams in sharia economy-based organizations with a sample of 85 respondents. The analysis model used is structural equation modeling (SEM) to test the relationship between virtual team dynamics, organizational performance, and the moderation role of remote work optimization strategies. The results showed that collaboration and communication have a significant influence on Optimizing Remote Work Strategies, while trust has no significant effect on Optimizing Remote Work Strategies. Collaboration and communication have a significant influence on Organization Performance, while trust has no significant effect on Organization Performance. In addition, Optimizing Remote Work Strategies has not been shown to have a significant effect on Organization Performance. The results of the study show that Optimizing Remote Work Strategies does not mediate the influence of organizational performance trust, The results of the study show that Optimizing Remote Work Strategies can mediate the influence of Collaboration on Organization Performance and the results of the study show that Optimizing Remote Work Strategies cannot mediate the influence of Communication on Organization Performance.
Keywords: Virtual Team Dynamics, Organization Performance, Optimizing Remote Work Strategies.
Utilizing Deep Learning for Field-Level Information Extraction from German Real Estate Tax Notices
Authors: Rombach Alexander M. , Lahann Johannes , Niesen Tim , Fettke Peter 
Published: December 2024

ABSTRACT
Document processing and related tasks such as information extraction represent a large portion of business workloads and therefore offer high potential for efficiency improvements and process automation. Although semistructured documents such as invoices and receipts have been extensively studied, tax notices represent a largely unexplored area due to their information richness and layout complexity. This article presents a study investigating the potential of deep learning-based information extraction for German real estate tax notices. We propose a hybrid approach based on the LayoutLM transformer model that uses textual, positional, and visual information as well as a rule-based information extraction. We show how such a system can be developed and integrated into the business workflow of organizations on the example of a German tax consulting firm. We also discuss the implications and key challenges that organizations face when planning to adopt such technologies.
Data Availability: Custom data and code are not publicly available. Relevant public source code is cited in the text.
JEL Classifications: M15; M40; M41.
Synthesis of Kantil Tone Using The Frequency Modulation Method
Authors: Suhartana I Ketut Gede , Dewi Ni Kadek Yulia , Giri Gst Ayu Vida Mastrika 
Published: December 2024

Music is a creative form of expression that utilizes sound arranged in specific patterns to create artistic works that are enjoyable to the listener. However, in music, excessive or continuous exposure to loud sounds can damage the hair cells in the ear, potentially leading to hearing loss or even deafness. One challenge in musical instrument craftsmanship is the variation in sound produced by different kantil artisans. These differences in sound output lead to inconsistencies in the rhythm of the angklung gamelan in Bali. This research addresses the issue by focusing on the process of synthesizing kantil sounds to achieve a more consistent output. The research begins by inputting audio files for each sound bar in format. The recorded audio data undergoes preprocessing using the Fast Fourier Transform (FFT) method, which extracts key features from the dataset, such as the fundamental frequency. Additionally, the Hilbert Transform is applied to obtain the optimal sound each blade, which will later be used in the Frequency Modulation process. Once preprocessing is completed on the dataset for each blade, the fundamental frequency and signal are acquired. To evaluate the accuracy of the synthesis, the Root Mean Square Error (RMSE) is calculated to compare the original signal with the synthesized signal. This step helps determine the degree of difference between the two signals. Ultimately, the result is a synthesized kantil sound that closely resembles the original, helping to standardize sound output among different craftsmen and ensuring consistency in musical performances
Evaluation of General Entrepreneurship Programme Curriculum in Tertiary Institutions in Ogun State, Nigeria
Authors: Rasaq Ramota Ajoke  , Ajisegiri Ruth O.  , Afolari Eyitayo Rufus Ifedayo  
Published: December 2024

Entrepreneurship programme has recently been discussed as the only solution to the unemployment ravaging the country. Using epistemological approach of the quantitative case study of the descriptive research design, this study assessed the general entrepreneurship programme curriculum in tertiary institutions in Ogun State. This was with a view to providing information on the extent of implementation of the entrepreneurship programme curriculum in Tertiary institutions in Ogun State, Nigeria. Directors of three higher institutions of learning (one University, one Polytechnic and one College of Education) were purposively selected based on compliance with the requirements for entrepreneurship programme. The results showed that the entrepreneurship programme curriculum in tertiary institutions in Ogun State was not effectively implemented. Also, it was discovered that only 37.4% of the courses had written curriculum. In addition, it was discovered that only 35.4% written curriculum are available for the entrepreneurship programme courses. Based on the findings of the study, it was therefore recommended that more skill acquisition courses should be embraced as stipulated by the federal government and experts should be employed to design written curriculum for entrepreneurship courses in tertiary institutions in Ogun state among others.
Application of the Rasch Model to the Evaluation of Biological Problems
Authors: Ida Elfira  , Abdul Razak  , Syamsurizal  , Helendra  
Published: December 2024

Evaluation of student abilities in Biology subjects often faces challenges in ensuring that the instruments used actually measure what they are supposed to measure. The data analysis used is the Rasch model, which is part of item response theory, offering a more accurate approach in analyzing evaluation data. This model allows the identification of items that are inappropriate or too difficult, as well as providing more in-depth information about individual student abilities. Through analysis of instruments and question items from 30 multiple choice questions that emphasize critical thinking skills, the aim of this research is to assess the quality of Biology questions for class X SMA. Testing was carried out using WinStep software and Rasch modeling analysis on 166 students from five high schools/vocational schools. The research method used is quantitative. The results of the instrument investigation show that the issue has very good dependability and the unidimensionality of the instrument is indicated by unexplained changes in the first differentiation. These results show that the Rasch test can help educators in selecting questions that meet the evaluation criteria and contribute to improving the quality of national education. The implications of this research are By applying the Rasch Model, educators can develop more accurate and fair evaluation tools, which are able to identify individual student difficulties and strengths.
ANALISIS VISUAL SCENE VIDEO GAME RED DEAD REDEMPTION 2
Authors: Gidion Barwida , I Gusti Made Budiarta  , I Nyoman Rediasa  
Published: December 2024

Penelitian ini bertujuan untuk menganalisis visual scene pada game Red Dead Redemption 2. Penelitian ini menggunakan metode penelitian deskriptif kualitatif dengan pengumpulan data melalui penelusuran informasi dari internet, laman resmi pengembang game, dan eksplorasi langsung pada game tersebut. Penelitian ini terdiri dari tiga fokus utama, yaitu aplikasi komputer yang digunakan dalam pembuatan scene, tahap-tahap pembuatan scene, dan penerapan unsur-unsur visual dalam game Red Dead Redemption 2. Data yang terkumpul dianalisis secara deskriptif kualitatif dan dilakukan analisis terhadap screenshot-screenshot dari game tersebut. Hasil penelitian ini menunjukkan bahwa pembuatan scene dalam game Red Dead Redemption 2 melibatkan penggunaan aplikasi komputer yang canggih, terutama Rockstar Advanced Game Engine (RAGE). Tahap-tahap pembuatan scene meliputi pre-production, production, dan post-production, dengan setiap tahap memiliki peran penting dalam menghasilkan scene yang berkualitas. Penerapan unsur-unsur visual dalam game ini mencakup penataan latar, penataan objek, penggunaan efek visual, dan rendering yang menghasilkan gambar yang mendekati nyata.

Kata-kata Kunci: visual scene, game Red Dead Redemption 2, aplikasi komputer
TINJAUAN LOCAL GENIUS PADA PEMBUATAN PERAHU TRADISIONAL PENANGKAP IKAN DI PESISIR SITUBONDO
Authors: Syaifullah Syaifullah , Koriawan Gede Eka Harsana , Sudita I Ketut 
Published: December 2024

Tinjauan Local Genius pada Pembuatan Perahu Tradisional Penangkap Ikan di Pesisir Situbondo dilakukan karena letak geografis Situbondo mayoritas laut sehingga mata pencaharian utama yaitu nelayan. Penelitian ini menggunakan metode penelitian kualitatif dan bertujuan mendeskripsikan 1) mengetahui proses pembuatan, alat dan bahan membuat perahu tradisional penangkap ikan pesisir Situbondo (local Genius) pesisir Keperan di Desa Tanjung Pecinan Kecamatan Mangaran Kabupaten Situbondo, 2) Mengetahui fungsi setiap bagian perahu tradisional penangkap ikan pesisir Situbondo (local Genius) pesisir Keperan di Desa Tanjung Pecinan Kecamatan Mangaran Kabupaten Situbondo. Jenis data primer dan data sekunder yang didapatkan dengan teknik pengumpulan data meliputi observasi, wawancara, dokumentasi dan kepustakaan. Hasil penelitian ini menunjukkan deskripsi profil Desa Tanjung Pecinan Kecamatan Mangaran Kabupaten Situbondo, menjelaskan alat dan bahan, serta proses dengan teknik pembuatan perahu tradisional Situbondo. Selain itu juga menjelaskan fungsi pada bagian perahu tradisional penangkap ikan pesisir Situbondo (Local Genius) Pesisir Keperan di Desa Tanjung Pecinan Kecamatan Mangaran Kabupaten Situbondo. Local genius merupakan pencipta kebudayaan pribumi dengan modal ethos kerja yang baik. Kesimpulan dari penelitian yang dilakukan adalah proses pembuatan perahu meliputi survei dan pengambilan bahan baku, pembagian batang, pembentukan perahu, penghalusan, penyelesaian, uji kelayakan perahu, dan upacara selametan sebelum digunakan sebagai transportasi laut penangkapan ikan. Penelitian ini diharapkan menjadi acuan peneliti lain dalam mengembangkan local genius terhadap pembuatan perahu tradisional. Selain itu juga, menjadikan maha karya daerah untuk menunjang perekonomian dan melestarikan kesenian dan budaya. Penelitian ini nantinya dapat dikembangkan menjadi pengelolaan karya masyarakat berupa perahu menjadi sarana pengembangan pariwisata modernisasi namun tidak menghilangkan ciri khas budaya setempat.
Kata Kunci: Local Genius, Perahu Tradisional, Pesisir Situbondo.
PERKEMBANGAN PENERAPAN BIM PADA PROYEK STRATEGIS NASIONAL BENDUNGAN DI INDONESIA OLEH PT WASKITA KARYA (PERSERO) TBK
Authors: Sarifah Fitriana , Radena Rayza Fitri , Hasna Destira Ghaida , Desmayanti Devi , Purnama Rangga Arya , Kania Gina 
Published: December 2024

Proyek Strategis Nasional (PSN) termasuk bendungan diorientasikan untuk pemerataan pembangunan dan peningkatan pertumbuhan sehingga meningkatkan pembangunan daerah dan kesejahteraan masyarakat. Bendungan yang termasuk PSN merupakan bendungan multimanfaat yang dimanfaatkan untuk memfasilitasi kebutuhan air baku, irigasi, listrik, pariwisata, perikanan, dan lain-lain. Pembangunan bendungan tersebut merupakan proyek di bawah Kementerian Pekerjaan Umum dan Perumahan Rakyat (PUPR). Berdasarkan surat edaran, Direktorat Jenderal Sumber Daya Air PUPR pada tahun 2023, bendungan yang termasuk PSN harus menerapkan Building Information Modelling (BIM). Meski peraturan BIM pada bendungan baru ada tahun 2023, BIM pada proyek konstruksi terutama Badan Usaha Milik Negara konstruksi dimulai pada akhir tahun 2016. Salah satu BUMN konstruksi yaitu PT Waskita Karya (Persero) Tbk (WSKT) mengerjakan 11 PSN bendungan dimana beberapa bendungan mulai dibangun pada tahun 2016. Tujuan penelitian ini diantaranya menganalisis apakah WSKT menerapkan BIM pada paket proyek 11 bendungan yang dibangun oleh WSKT. Penelitian ini juga menganalisis bagaimanakah penerapan BIM pada masing-masing paket proyek bendungan yang dibangun oleh WSKT. Penelitian ini menggunakan metode analisis berupa data sekunder berupa data perusahaan yang bisa diakses publik dari seperti website dan media sosial resmi sebagai sumber yang terpercaya dari WSKT, PUPR, dan instansi/lembaga terkait BIM dan pembangunan proyek bendungan hingga jurnal mengenai penerapan BIM pada proyek bendungan. PT Waskita Karya (Persero) Tbk telah menerapkan BIM pada pengerjaan seluruh Proyek Nasional Strategis (PSN) bendungan sejak tahun 2016. Level penerapan BIM pada proyek bendungan yang dibangun WSKT yang sudah hingga yaitu 7D (facilities management) seperti pada Bendungan Jragung
ON THE IONIC RADIUS OF METHYLAMMONIUM IN HYBRID ORGANIC-INORGANIC PEROVSKITE PHASES
Authors: Sidey V.I. 
Published: December 2024

Hybrid organic-inorganic perovskites ABX3 usually contain an organic cation A and an inorganic matrix formed from coordination octahedra [BX6], where B is a metal and X is a halogen. Predicting the formation of hybrid perovskite phases and modeling their structural parameters requires basic knowledge of the effective sizes (ionic radii) of the constituent components; however, the previously proposed approach to estimate the effective ionic radius of a particular organic cation A based on its molecular geometry apparently does not correspond to the hard spheres model, within the framework of which the vast majority of ionic radii systems and the main criteria for assessing the stability of perovskite structures were developed.
To independently estimate the effective ionic radius of methylammonium CH3NH3+, which is a component of a number of perovskite structures, a scheme for modeling the lattice parameter of halide cubic perovskites ABX3 was developed by using multiple linear regression analysis based on the effective ionic radii of inorganic components with the corresponding coordination numbers intrinsic for perovskites. Using the found direct and inverse correlations between the effective ionic radius of the cation A and the cubic lattice parameter of perovskite, as well as numerical data of the lattice parameters of the known cubic hybrid perovskite phases (CH3NH3)PbCl3 and (CH3NH3)PbBr3, the value of the effective ionic radius of methylammonium CH3NH3+ was first estimated as ~1.9 Å, which is significantly different from the value of 2.17 Å obtained within the framework of the approach based on the molecular geometry.