bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cilia dysfunction in the lateral ventricles after neonatal intraventricular hemorrhage does not lead to functional changes in cilia-based CSF flow networks
Authors: Pan Shelei , Ramagiri Sruthi , Yang Lihua , Giles David A. , Xu Isabella , Bonilla Maria Garcia , DeFreitas Dakota , Siderowf Lillian W. , Halupnik Grace L. , Koneru Shriya , Koller Gretchen M. , Polavarapu Srinandan , Gupta Deepesh K. , Krishnamoorthy Praveen , Miller Mark J. , Esakky Prabagaran , Limbrick David D. , Bayly Phillip V. , Horani Amjad , Brody Steven L. , Mahjoub Moe R. , Strahle Jennifer M. 
Published: November 2024

AbstractIntraventricular hemorrhage (IVH) has long been thought to lead to motile cilia dysfunction whereby intraventricular blood breakdown products damage and slough cilia from the ependymal wall. However, specifically how IVH may affect cilia development, structure, and transcriptional activation is not well-understood. Moreover, the impact of blood breakdown product-mediated cilia damage on the functional organization of cilia-based CSF flow networks is unknown. Here, we show hemoglobin exposure affects the number of ciliated ependymal cells in the lateral ventricle (LV) but does not impactin vitrobeat frequency of the remaining cilia. Ultrastructurally, IVH decreases the total number of ciliary tufts without impacting axoneme structure. IVH does not result in changes in the expression of cilia-related genes and instead leads to downregulation of neurogenesis markers in parallel with innate immune upregulation. Functionally, we identify three previously uncharacterized cilia-mediated CSF flow domains in the LV lateral wall and show that IVH does not result in widespread disruption of their functional organization. These data de-emphasize cilia as a major contributor to global CSF dysfunction after IVH, and instead call attention to preserving the neurodevelopmental environment and preventing runaway innate immune system activation, as considerations to developing treatment strategies to prevent posthemorrhagic hydrocephalus and other neurodevelopmental sequelae.
Mapping canopy foliar functional traits in a mixed temperate forest using imaging spectroscopy
Authors: Gravel Alice , Laliberté Etienne 
Published: November 2024

AbstractFoliar functional traits are key drivers of ecological processes in forests. Despite progress in forest foliar trait mapping from imaging spectroscopy, there is a need to build environment-specific, spectra-trait models trained from tree-level measurements to improve the accuracy of local trait maps.We mapped 12 foliar functional traits in a mixed temperate forest using airborne imaging spectroscopy. Top-of-canopy foliar samples from tree crowns (n = 166), representing a total of 16 species, were collected using a drone platform to measure foliar traits for individual trees, from which tree-level crown spectra were also determined. Partial least squares regression (PLSR) models were used to predict foliar traits from tree-level reflectance spectra (400-2400 nm).These models predicted leaf mass per area (LMA), specific leaf area (SLA) and equivalent water thickness (EWT) with high accuracy (R2> 0.8, %RMSE < 15). Models for pigment, nitrogen and cellulose concentrations showed a moderate performance (R2= 0.53–0.68, %RMSE = 17.24–21.31). Poorest performance was observed for lignin, carbon, leaf dry mass content (LDMC) and hemicellulose (R2= 0.24–0.44, %RMSE = 20.67–26.13).High-resolution (1.25 m pixel-1) foliar trait maps were produced for the entire 16-km2study area. Our study adds to the extensive research aiming to use remote sensing to monitor forest functional trait biodiversity at larger scales and provides models that capture intraspecific variation across many tree species from a mixed temperate forest in eastern Canada.
Personalized cancer treatment strategies incorporating irreversible and reversible drug resistance mechanisms
Authors: He Wei , McCoy Matthew D. , Riggins Rebecca B. , Beckman Robert A. , Yeang Chen-Hsiang 
Published: November 2024

ABSTRACTDespite advances in targeted cancer therapy, the promise of precision medicine has been limited by resistance to these treatments. In this study, we propose a mathematical modelling framework incorporating cellular heterogeneity, genetic evolutionary dynamics, and non-genetic plasticity, accounting for both irreversible and reversible drug resistance. Previously we proposed Dynamic Precision Medicine (DPM), a personalized treatment strategy that designed individualized treatment sequences by simulations of irreversible genetic evolutionary dynamics in a heterogeneous tumor. Here we apply DPM to the joint model of reversible and irreversible drug resistance mechanisms, analyze the simulation results and compare the efficacy of various treatment strategies. The results indicate that this enhanced version of DPM results in superior patient outcomes compared with current personalized medicine treatment approaches. Our results provide insights into cancer treatment strategies for heterogeneous tumors with genetic evolutionary dynamics and non-genetic cellular plasticity, potentially leading to improvements in survival time for cancer patients.
Visually-guided compensation of deafening-induced song deterioration
Authors: Rolland M , Zai A , Hahnloser RHR , Del Negro C , Giret N 
Published: November 2024

AbstractHuman language learning and maintenance depend primarily on auditory feedback but are also shaped by other sensory modalities. Individuals who become deaf after learning to speak (post-lingual deafness) experience a gradual decline in their language abilities. A similar process occurs in songbirds, where deafness leads to progressive song deterioration. However, songbirds can modify their songs using non-auditory cues, challenging the prevailing assumption that auditory feedback is essential for vocal control. In this study, we investigated whether deafened birds could use visual cues to prevent or limit song deterioration. We developed a new metric for assessing syllable deterioration called the spectrogram divergence score. We then trained deafened birds in a behavioral task where the spectrogram divergence score of a target syllable was computed in real-time, triggering a contingent visual stimulus based on the score. Birds exposed to the contingent visual stimulus—a brief light extinction—showed more stable song syllables than birds that received either no light extinction or randomly triggered light extinction. Notably, this effect was specific to the targeted syllable and did not influence other syllables. This study demonstrates that deafness-induced song deterioration in birds can be partially mitigated with visual cues.
Strategic nature of corporate social responsibility, competitive performance, innovation capability and environmental uncertainty
Authors: Mohammad Haruna Isa , Marcel Daniel 
Published: November 2024

PurposeThe goal of this work is to evaluate how corporate social responsibility (CSR) affects competitive performance in Nigeria's banking industry, with innovation capability acting as a mediator and environmental uncertainty as a moderating factor.Design/methodology/approachThe banking industry in Nigeria served as the site for the empirical investigation. Employees at deposit money institutions received a questionnaire. Direct and mediating effects and the moderating role were thus examined utilizing a final sample of 267 cases using consistent partial least squares structural equation modeling with ADANCO 2.2.1.FindingsThe data shows that CSR has both a significant strategic impact on innovation capability and a competitive innovation capability. In contrast, the outcome shows a strong effect of CSR's strategic character on performance in the marketplace. Furthermore, evidence for mediating and moderating effects was provided.Research limitations/implicationsThe study was restricted to Nigerian banking institutions. Additionally, data on competitive performance were acquired from employees' perspectives, while considering the competitive performance of their rivals.Originality/valueThe primary contribution of this paper is the empirical investigation of the mediating impact of innovation capability and the moderating function of environmental uncertainty in banking organizations that use a CSR strategy to attain competitive performance.
Qualitative research in the Academy of Human Resource Development-sponsored journals
Authors: Johnson Karen R. , Nery-Kjerfve Tania , Yeager Katherine , McLean Gary N. 
Published: November 2024

Purpose
Qualitative paradigmatic perspectives are increasingly recognized as providing in-depth, rich and nuanced interpretations and critiques of complex phenomena. Nonetheless, positivist and post-positivist epistemologies still dominate social science disciplines. The authors were unable to identify published information on the state of qualitative research in human resource development (HRD) despite the numerous theoretical foundations, epistemological stances and global approaches that shape HRD. To fill this gap, this study determined the prevalence of qualitative designs, data collection methods and data analysis techniques that have been used in Academy of Human Resource Development (AHRD)-sponsored journals. This study identified gaps in the use of qualitative research to be explored by HRD scholars to advance research and practice.

Design/methodology/approach
A descriptive case study approach was used to determine the state of qualitative research in three AHRD-sponsored journals.

Findings
Qualitative articles have increased in number but still account for a lower percentage of articles when compared with other peer-reviewed articles, including quantitative methodologies and conceptual papers. Most articles lacked grounding in stated ontology and epistemology needed to guide researchers’ investigations, potentially leading to weakened methodological choices, interpretations and authenticity of conclusions.

Research limitations/implications
To provide in-depth understanding of HRD-related phenomena, all important elements of qualitative articles should be addressed to strengthen the credibility and authenticity of the research process. Qualitative theorists and researchers can build on and embrace the soundness of qualitative research and theories in HRD. Expanding on the credibility and authenticity of rigorously conducted qualitative research will help to broaden the perspectives of researchers who may be hesitant to explore this methodology of inquiry. This will strengthen methodological sophistication and expand the knowledge base of qualitative research.

Practical implications
HRD professors/instructors will find this study to be a useful guide for graduate students who are exploring and using qualitative inquiry for their research and for understanding others’ research. Practitioners will also find it useful to understand HRD research to determine possible interventions in their workplaces.

Originality/value
This study identifies trends and patterns of epistemologies and methods used in HRD qualitative articles and provides a foundation on which to build future studies and establish unexplored, unconventional qualitative methodologies and methods.
Strategizing blockchain adoption in public cultural services: a comprehensive scoping review
Authors: Rubino Federica , Agostino Deborah , Spallazzo Davide 
Published: November 2024

PurposeThis paper explores the application of blockchain technology in the public cultural sector, where adoption remains limited despite its potential. The study identifies major use case scenarios and empirical examples of blockchain adoption in public sector cultural services through a scoping literature review.Design/methodology/approachA scoping literature review was conducted to map research and conceptual approaches to blockchain technology in the public cultural sector, focusing on key use cases emerging and empirical examples.FindingsThe review reveals that while blockchain has the potential to enhance public cultural services, its adoption is still in its early stages. Identified use cases include tokenization of cultural assets, digital rights management and decentralized funding models. Empirical examples in the public cultural sector are sparse, and the impact of the technology remains largely theoretical.Research limitations/implicationsThe study is limited by the scarcity of empirical data on blockchain adoption in public cultural services. Future research should focus on in-depth case studies and empirical analyses to understand the practical implications of blockchain in this sector.Practical implicationsPublic sector organizations offering cultural services may use these insights to guide blockchain adoption and implementation decisions.Social implicationsBlockchain adoption in public cultural services has the potential to democratize access, enhance transparency and foster community engagement, contributing to a more inclusive and participatory cultural ecosystem.Originality/valueThis paper contributes to the emerging discourse on blockchain in the public sector, focusing on the often-overlooked cultural services. It highlights the benefits and challenges of blockchain adoption in this sector, providing insights for future research and policy decisions.
Performance analysis of the Next Eleven countries regarding climate change for the selected years
Authors: Tezcan Nuray 
Published: November 2024

PurposeIn the Next Eleven (N-11) countries, which are considered emerging investment markets, energy consumption is increasing in parallel with the growing economy. This situation negatively affects global warming and climate change, which are the biggest environmental problems of today. From this point of view, the purpose of the study is to determine the performance of the N-11 countries in terms of energy use and climate change for the period between 2010 and 2022 based on the indicators of Sustainable Development Goal (SDG) 7 and SDG 13 to be reached until 2030.Design/methodology/approachGrey relational analysis (GRA), one of the multi-criteria decision-making techniques, was used to assess the performance of the N-11 countries in the study. Additionally, the entropy method was employed in determining weights needed in GRA. The indicators were obtained from the World Development Indicators database, World Bank. Performance analyses were conducted for the years 2010, 2015 and 2022, respectively.FindingsAccording to the results obtained, it has been found that Bangladesh, the Philippines and Egypt have the three highest scores, while Mexico, Indonesia and Iran have the three lowest scores. In 2022, Nigeria is placed instead of Mexico in this group. It is observed that the performance scores of the countries have either remained the same or increased slightly over the years. This indicates that it is difficult to reach the 2030 targets.Originality/valueThis study is the first attempt to measure the performance of N-11 countries on climate change using multi-criteria decision-making. In this study, the performance scores obtained for the selected years were compared. Thus, it is observed whether there is an improvement in the performance scores of the countries during the analysis period.
Impact of country-specific business integrity and firm-specific ESG on earnings quality: evidence from EU civil law jurisdictions
Authors: Lindahl Frederick , Kantola Satu-Päivi , Schadewitz Hannu 
Published: November 2024

Purpose
This paper aims to examine whether variations in country-specific business integrity (BI) and firm-specific environmental, social and governance (ESG) dimensions can explain variations in earnings quality (EQ) in Northern and Southern EU civil law countries.

Design/methodology/approach
Regarding EQ, the analysis builds on the “small gain, small loss” (SGSL) model of Burgstahler and Dichev (1997) and Burgstahler and Chuk (2015). The authors explain SGSL with the BI. Southern Europe or “Club Med” is typically associated with a less rigorous institutional regime than Northern Europe.

Findings
Results evidenced higher EQ in the Northern EU compared with the Southern EU. Furthermore, EQ is explained successfully with the Business Integrity Index (BII) and ESG. The results suggest that BII and ESG represent different dimensions, and, therefore, both should be included in the models explaining EQ.

Practical implications
The results show that the Northern EU civil law countries have higher EQ compared with the Southern EU civil law countries. The difference is explained by the BII variable. For the Southern EU, legislators and other public policy decision-makers should build up and apply tools to limit and fight corruption in those jurisdictions. The impactful elimination of corruption would, in turn, establish a firmer basis to foster ethical behavior and financial market sophistication developments.

Originality/value
The study offers additional insights on the determinants of EQ in the EU civil law countries. The prior literature has argued that, categorically, in common law countries firms engage in higher-quality reporting than those in civil law countries. The results evidence that EQ varies within the EU civil law countries; that is, a country’s BI and firm-specific ESG contribute to the explanation for EQ. A more specific explanation for the reasons in the EQ “within” civil law jurisdictions could be related to legislators and other public policy decision-makers in charge of establishing regimes and public policies supporting high-quality accounting.
Seed dispersal mechanisms modulate Janzen‐Connell effects in Mediterranean forests through antagonists and mutualists
Authors: Perea Antonio J. , Wiegand Thorsten , Bastida Jesús M. , Pajares‐Murgó Mariona , Cano Domingo , López‐García Álvaro , Pomarede Lise C. , Prieto‐Rubio Jorge , Rey Pedro J. , Garrido José L. , Alcántara Julio M. 
Published: November 2024

Abstract

Antagonist and mutualist organisms mediate the long‐standing, classical Janzen‐Connell effects and yet they are rarely investigated, especially when they share plant species hosts. Here, we propose that plant species create an “antagonists‐ and mutualist‐scape” which, coupled with seed dispersal mechanisms, will govern the relative survival rates of juveniles within the landscape and influence their later life stages.

We combined data on fully stem mapped plots of woody plant species in two Mediterranean forests (Mixed Forest of Segura [MFS] and Mixed Forest of Jaen [MFJ]) with data on the associated communities of leaf epiphytic fungi, leaf pathogens, sap‐sucking insects and chewer insects hosted by each woody plant species. This allowed us to indirectly test the Janzen‐Connell hypothesis by investigating the placement of plant species with contrasting seed dispersal mechanisms (fleshy fruited vs. dry‐fruited plant) within the antagonists‐ and mutualist‐scapes.

More specifically, we determined the degree of host‐specificity of plant‐associated organisms and defined the antagonist‐ or mutualist‐scapes for focal plants as the mean number of antagonist‐ or mutualist species the focal plant shares with its (sapling or adult) plant neighbours, respectively. We then applied multivariate spatial point pattern analysis to test whether saplings and adults of the focal species tended to be located in favourable sites of the antagonist‐scapes (i.e. were neighboured by fewer antagonist species than expected) or were distributed independently of the antagonist‐scapes.

A substantial proportion of organisms was associated with more than one plant species, with organisms at MFJ being more “host‐specific” than organisms at MFS. Our spatial analyses revealed spatial patterns that differed strongly between fleshy‐fruited and dry‐fruited species and were, in most cases, consistent with our expectations. For example, saplings of dry‐fruited species were placed in favourable sites in the saplings antagonist‐scapes, whereas saplings of fleshy‐fruited species were independently placed with respect to the saplings antagonist‐scapes.

Our results show how the placement of plant species within the antagonist‐scapes changes during the ontogeny, and how this is influenced by Janzen‐Connell effects and the seed dispersal mechanisms. We provide a new approach and indications about the importance of generalist antagonists and mutualists as drivers of the spatial assembly of plant communities.

Read the free Plain Language Summary for this article on the Journal blog.
Understanding the ecological versatility of Tetracladium species in temperate forest soils
Authors: Lazar Anna , Phillips Richard P. , Kivlin Stephanie , Bending Gary D. , Mushinski Ryan M. 
Published: November 2024

AbstractAlthough Tetracladium species have traditionally been studied as aquatic saprotrophs, the growing number of metagenomic and metabarcoding reports detecting them in soil environments raises important questions about their ecological adaptability and versatility. We investigated the factors associated with the relative abundance, diversity and ecological dynamics of Tetracladium in temperate forest soils. Through amplicon sequencing of soil samples collected from 54 stands in six forest sites across the eastern United States, we identified 29 distinct Amplicon Sequence Variants (ASVs) representing Tetracladium, with large differences in relative abundance and small changes in ASV community composition among sites. Tetracladium richness was positively related to soil pH, soil temperature, total sulphur and silt content, and negatively related to plant litter quality, such as the lignin‐to‐nitrogen ratio and the lignocellulose index. Co‐occurrence network analysis indicated negative relationships between Tetracladium and other abundant fungal groups, including ectomycorrhizal and arbuscular mycorrhizal fungi. Collectively, our findings highlight the ecological significance of Tetracladium in temperate forest soils and emphasize the importance of site‐specific factors and microbial interactions in shaping their distribution patterns and ecological dynamics.
Critical crisis management competencies: Perspectives from universities of technology leadership
Authors: Pharaoh Courtley 
Published: November 2024

AbstractThe South African Higher Education sector has faced challenging times recently, notably the #FeesMustFall student protest crisis, which inflicted damages exceeding R1 billion, and the COVID‐19 pandemic, claiming over 102,000 lives in the nation. Against this backdrop, a critical investigation has been initiated to discern the indispensable crisis management competencies required by executive management members of Universities of Technology (UoT) in South Africa. This exploratory study emphasises the higher education landscape, recognising its pivotal role in national development. Employing qualitative face‐to‐face interviews, the research aims to delve into the experiences of executive management members, providing insights into the nuanced demands of crisis management within the higher education context. In response to the challenges posed by the COVID‐19 pandemic, the study adapted by utilising online face‐to‐face meetings, ensuring a thorough exploration of crisis management competencies. Beyond mere identification, the research attempts to elucidate the profound significance of these competencies within the unique context of higher education institutions during crises. The findings contribute not only to the broader understanding of crisis management but also underscore the particular relevance and implications for the resilience and adaptability of South African UoT in the face of multifaceted challenges.