bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modifications in small nuclear RNAs and their roles in spliceosome assembly and function
Authors: Bohnsack Markus T. , Sloan Katherine E. 
Published: June 2018

Abstract
Modifications in cellular RNAs have emerged as key regulators of all aspects of gene expression, including pre-mRNA splicing. During spliceosome assembly and function, the small nuclear RNAs (snRNAs) form numerous dynamic RNA-RNA and RNA-protein interactions, which are required for spliceosome assembly, correct positioning of the spliceosome on substrate pre-mRNAs and catalysis. The human snRNAs contain several base methylations as well as a myriad of pseudouridines and 2′-O-methylated nucleotides, which are largely introduced by small Cajal body-specific ribonucleoproteins (scaRNPs). Modified nucleotides typically cluster in functionally important regions of the snRNAs, suggesting that their presence could optimise the interactions of snRNAs with each other or with pre-mRNAs, or may affect the binding of spliceosomal proteins. snRNA modifications appear to play important roles in snRNP biogenesis and spliceosome assembly, and have also been proposed to influence the efficiency and fidelity of pre-mRNA splicing. Interestingly, alterations in the modification status of snRNAs have recently been observed in different cellular conditions, implying that some snRNA modifications are dynamic and raising the possibility that these modifications may fine-tune the spliceosome for particular functions. Here, we review the current knowledge on the snRNA modification machinery and discuss the timing, functions and dynamics of modifications in snRNAs.
Microstructure and Mechanical Properties of Friction Stir Processed A356 Cast Al under Air Cooling and Water Cooling
Authors: Ai Xinxin , Yue Yumei 
Published: June 2018

AbstractIn this work, friction stir processing (FSP) was used to modify the microstructure of A356 cast aluminum alloy under air cooling and water cooling conditions. The microstructure and mechanical properties of air cooling and water cooling FSP specimens and their differences were mainly discussed. Results show that the grains can be significantly refined after FSP under both air cooling and water cooling conditions. The water cooling FSP specimen shows much smaller grains than the air cooling FSP specimen due to lower temperature. Similarly, the Si particles of water cooling FSP specimen show much smaller sizes and better distribution. Both the air cooling FSP specimen and water cooling FSP specimen own much higher tensile strength and elongation than A356 base material (BM). In particular, the tensile strength and elongation of water cooling specimen are respectively 231 Mpa and 14.15%, which are equal to 186.3% and 1088.5% of the BM. Furthermore, the microhardness of water cooling FSP specimen is lower than that of the air cooling FSP specimen.
Wilhelm ,Kassandraʻ
Authors: Limmer-Kneitz Agnes 
Published: June 2018

AbstractThis paper is interested in the role and space ‘conservative’ poetical realist literature was granted in the German Empire’s 19th century public discourse around environmental pollution and its impact on social inequality. Wilhelm Raabe’s novel Pfister’s Mill serves as a case study, as this literary work discusses the unwanted side effects of the young nation state’s transformation from an agricultural to an industrial society based on a contemporaneous legal incident.
Edible Plant Oil Wastewater Treatment Using Electro-Fenton Technique: Experiment and Correlation
Authors: Davarnejad Reza , Mohajerani Seyed Amir 
Published: June 2018

Abstract
The edible plant oil production factories consume high amounts of water and contaminate the water resources. This type of wastewater consists of high chemical oxygen demand (COD) which should properly be treated by an efficient technique. Furthermore, it is containing some chemicals obtained from several sources such as H3PO4 (from hydration section), NaOH (from neutralization section) and citric acid (from nickel removal section). The conventional techniques cannot efficiently treat it which is full of COD. Therefore, the electro-Fenton process as a rapid, compact and efficient one has been encouraged to be applied. For this purpose, 47 experiments were designed and carried out using iron electrodes to evaluate the effects of five significant independent variables such as reaction time (min), pH, current density (mA/cm2), volume ratio of H2O2/wastewater (ml/l) and H2O2/Fe2+ molar ratio on the COD removal. Response surface methodology (RSM) was employed to assess individual and interactive effects of the parameters. The optimum conditions were experimentally obtained at reaction time of 87.33 min, pH of 3.03, current density of 57 mA/cm2, H2O2/wastewater volume ratio of 2.13 ml/l and H2O2/Fe2+ molar ratio of 3.61 for COD removal of 62.94 %.
Optimal Control of an Endoreversible Solar Power Plant
Authors: Schwalbe Karsten , Hoffmann Karl Heinz 
Published: June 2018

AbstractWhile in the classic Curzon–Ahlborn and Novikov engines the temperatures of the heat baths are kept fixed or follow a deterministic time function, it is the aim of this work to study the impact of fluctuating heat bath temperatures. As an example serves a solar power plant, where the stochastically varying cloud cover leads to fluctuations in the temperature of the hot heat bath. This solar thermal power plant is modeled as a stochastic endoreversible system. On the basis of this model the maximum expected work output of the power plant and the corresponding optimal control policy is derived. For the considered system it is found that the maximum expected work output changes with the reversion speed of the hot temperature depending on the relation of the starting hot temperature and the temperature of the power plant’s receiver. Additionally, it is found that the maximum expected work output increases with the hot temperature’s fluctuation strength.
A network diffusion ranking family that includes the methods of Markov, Massey, and Colley
Authors: Devlin Stephen , Treloar Thomas 
Published: June 2018

Abstract
We present a one parameter family of ratings and rankings that includes the Markov method, as well as the methods of Colley and Massey as particular cases. The rankings are based on a natural network diffusion process that unites the methodologies above in a common framework and brings strong intuition to how and why they differ. We also explore the behavior of the ranking family using both real and simulated data.
An algorithm based on a new DQM with modified exponential cubic B-splines for solving hyperbolic telegraph equation in (2 + 1) dimension
Authors: Singh Brajesh Kumar , Kumar Pramod 
Published: June 2018

AbstractIn this paper, a new methodmodified exponential cubic B-Spline differential quadrature method(mExp-DQM) has been developed for space discretization together with a time integration algorithm for numeric study of (2 + 1) dimensional hyperbolic telegraph equations. The mExp-DQM (i.e., differential quadrature method with modified exponential cubic B-splines as new basis) reduces the problem into an amenable system of ordinary differential equations (ODEs), in time. The time integration SSP-RK54 algorithm has been adopted to solve the resulting system of ODEs. The proposed method is shown stable by computing the eigenvalues of the coefficients matrices while the accuracy of the method is illustrated in terms ofL2andL∞error norms for each problem. A comparison of mExp-DQM solutions with the results of the other numerical methods has been carried out for various space sizes and time step sizes.
An expedient synthesis of 6-amino-5-[(4-hydroxy-2-oxo-2H-chromen-3-yl)(aryl)methyl]-1,3-dimethyl-2,4,6(1H,3H)-pyrimidinedione derivatives using Fe3O4@TiO2 nanocomposite as an efficient, magnetically separable, and reusable catalyst
Authors: Fakheri-Vayeghan Sakineh , Abdolmohammadi Shahrzad , Kia-Kojoori Reza 
Published: June 2018

Abstract
An efficient methodology dealing with the Fe3O4@TiO2 nanocomposite-catalyzed direct condensation reaction of 4-hydroxycoumarin, aromatic aldehydes, and 6-amino-1,3-dimethyluracil in aqueous media at room temperature is reported. This new process has been successfully applied to the synthesis of 6-amino-5-[(4-hydroxy-2-oxo-2H-chromen-3-yl)(aryl)methyl]-1,3-dimethyl-2,4,6(1H,3H)-pyrimidinediones in high to excellent yields within 2–3 h.
An Arcadian Poet in a Baroque City: Cláudio Manuel da Costa’s Urban Pastorals, Family Life, and the Appearance of Race
Authors: Carvalho Bruno 
Published: June 2018

With focus on Cláudio Manuel da Costa and his life in eighteenth-century Minas Gerais, this article places into dialogue seemingly contradictory notions of baroque urbanism, art, and poetics. It explores how Cláudio’s work engages baroque and Arcadian tropes, re-writing pastoral conventions with awareness of the production of nature through artifice. Some of his poems emerge as narratives of wilderness subsumed by colonial forces, others offer clues about his relationship with Francisca Arcângela de Souza, a woman of African descent (archival findings about her are presented here for the first time). Cláudio Manuel da Costa, a writer and public gure of many masks, helps us to make sense of tensions, changes, and apparent paradoxes of the period.
José da Silva Lisboa and the Pathology of Revolution
Authors: Monteiro Pedro Meira 
Published: June 2018

Focusing on José da Silva Lisboa’s Constituição Moral e Deveres do Cidadão (1824/1825), this article explores how the image of Revolution, modeled on the "catastrophic" experiences of France and Haiti, projects itself onto the scenario of the nascent Brazilian empire. For Lisboa, the moralizing discourse should be capable of founding a new order in the tropics, of protecting "Brazilian youth" from the seduction of renovating principles, of maintaining well-tied the knots of a social fabric threatened by the madness of revolutionaries, who brought to the horizon of a young nation the danger of dissolution and corruption of the body politic.
A critical analysis of intellectual capital research in universities
Authors: Bratianu Constantin 
Published: June 2018

Abstract
Researching on the intellectual capital in universities is a challenging task due to the complexity of the intellectual processes within any university and the fuzziness of the basic concepts and methodologies developed so far. Universities are among the oldest social institutions and they concentrate high densities of intellectual capital. The concept of intellectual capital has been created as a result of increasing significantly the role of intangibles in economy and of the dramatic split between the book value and market value of the new companies based on intensive knowledge processes. Intellectual capital represents that component of the total capital of any organization which incorporates all intangible resources and their transformations. Intellectual capital is highly nonlinear by comparison with the capital containing tangible resources, which has a linear structure and Newtonian dynamics. The canonical structure of the intellectual capital is composed of human capital, structural capital, and relationship capital. This structural model has been used extensively in evaluating and reporting the intellectual capital of organizations, including universities. However, the Newtonian paradigm constitutes an important limitation in understanding properly both the nature of intellectual capital and how to manage it efficiently. Our research question is focused on how we can change that paradigm with a better one able to represents more adequately the nature and the basic structure of the intellectual capital. The methodology we used is based on in depth literature analysis, metaphorical thinking, critical thinking, and the multifield theory of knowledge. As a result of our research, this paper presents a new approach of the intellectual capital and its application to the universities.
A pragmatic view on the financial theories
Authors: Chișu Mihai 
Published: June 2018

Abstract
This presentation reviews some real examples from a trading daily basis behavior proving the sentiment is one of the most important drivers when it comes to investment decision. During decades of studying and observing the financial markets we have seen different approaches in the light of many prestigious writers. Are we rational enough to be good candidates for Fama’s theory of Efficient Market Hypothesis? Is it true what John Maynard Keynes stated 90 years ago when he said „the market is subject to waves of optimistic and pessimistic sentiment”? Is the financial behavior the new trend in the financial markets? Are Daniel Kahneman (Nobel Prize winner 2002) and Amos Tversky the new challengers in the market theories league? Future research should concentrate on various symptoms of sentiment and what makes investors become prone to sentiment. This is an important issue to be debated since investors constantly have to analyze, process and interpret huge data of information which provides the basis for their actions.
Reserch on implementing education for sustainable development
Authors: Dima Alina-Mihaela , Meghisan-Toma Georgeta-Madalina 
Published: June 2018

Abstract
The current research aims to identify the main directions to implement sustainability in education through curriculum; interdisciplinary/ transdiciplinary approach; business environment; entrepreneurship and innovation. In order to fulfil the objectives of the current study, a questionnairebased survey was sent by email to UNESCO Chairs from Balkan Region and the responses were analysed using descriptive statistics and factor analysis. According to the results, UNESCO chairs are working towards the main goals for higher education in the EU through some instruments: Establishing the main directions for a quality education; Establishing the relevant directions towards the implementation of sustainability in education through curriculum; Establishing the relevant directions towards the implementation of sustainability in education by an interdisciplinary/ transdisciplinary approach; Establishing the relevant directions towards the implementation of sustainability in education in collaboration with the business environment; Establishing the main directions in the field of education for entrepreneurship and innovation.
Adoption of Circular Economy concepts and practices by Portuguese Citizens and Companies
Authors: Fonseca Luis Miguel , Domingues José Pedro 
Published: June 2018

Abstract
The concept of Circular Economy is an emerging topic and the European Union has established a European Circular Economy Strategy in 2015. Although this concept originates from Europe, there is also an increased attention to the Circular Economy in China and the country has implemented regulatory controls in that regard. The scientific interest on this issue has been increasing and a great deal of research articles has been published in the soundest scientific journals recently. The concept of Circular Economy aims to address the need to pursue economic growth, while protecting the environment (including existing resource limitations and pollution prevention), and paying attention to societal and people needs and expectations. The adoption of Circular Economy can generate considerable tangible and intangible benefits such as new opportunities for co-operation, access to markets and innovation of products and services and, simultaneously, improving the environmental performance and mitigating the risks of resource scarcity. This creates value for the companies and their stakeholders and contributes to enduring success. To assess if the Portuguese citizens and companies support and adopt a “Circular Economy behavior”, an online survey was carried out amongst ISEP - P. Porto population, yielding more than 200 valid responses (65% of the total responses were provided by students). Based on the survey outputs (assessment supported in a 5 point Likert type scale), the following conclusions can be drawn: Most respondents agree that it is beneficial both for the environment and the economy the adoption of production systems based on used products and parts reuse and recycling; There is also agreement that the selective collection of waste should be the base to develop new products and there is significant support for a “zero waste economy” in which all used products or materials are reused or recycled. However, the respondents consider that the Portuguese citizens do not always segregate and deposit their waste in the appropriate waste containers and the same applies to companies that do not segregate and manage their waste adopting a systematically environmentally responsible approach. Moreover, they consider that the Portuguese legislation only mildly supports the adoption, both from citizens and companies, of environmental friendly practices. These conclusions reinforce the need to strengthen Circular Economy concepts and approaches within the Portuguese government, citizens, and companies.
High energy, increased balance and self control, the necessary conditions for performance and a good health
Authors: Mândrea Lucian T. , Curta Ioan I. , Marosy Zoltan Z. 
Published: June 2018

Abstract
The research purpose is to present the possibilities of the human being which are useful in order to improve the personal level of energy and to achieve an increased balance and a strong self control. These are the necessary conditions to be performed and in the same time to maintain a good health. Humans usually use energy from external sources. But, first of all, by employing different personal techniques, one can reach a high level of balance, energy and self control. These are the simplest, the fastest, the most efficient, the most economical and also ecological ways to have energy. If these attempts are efficient, you are first of all warm, then less ill and stressed. Everybody should try these kinds of methods first. A comparison was made between the results from two consecutive years, obtained by measuring the subject using a Bio-Well device. It results an increase of 23% in the energy level, in the conditions that the other parameters are optimal. The general balance reached the value of 99.97%. The authors proved, with the occasion of these original measurements, that a perfect balance can be reached. Another set of original and new measurements reveal the possibility of the human being to have a good self control. The subject proposed and succeeded in moving the second body energy centre by his own will, which is the most important energy centre of the body in the Zen-Buddhism. This is a remarkable completely original result obtained, maybe, for the first time in the world. In principle, we could control then the positions of the all seven energy centers, one by one. And so, the whole balance of the body. Also, in this way an incredible personal control and level of performance and also a high level of happiness can be achieved.
Innovation needs deregulation: the case of taxi and private hire companies
Authors: Nasulea Christian , Nasulea Diana Florentina , Mic Stelian Mihai 
Published: June 2018

Abstract
Every year seems to bring about new technologies that radically change the way we do things. New innovative business models come to life, that change the way the world works so much that a shift of mindset is required if we are to keep up. These days, the largest transport company in the world owns no cars, the largest accommodation provider owns no real estate, the largest retailer by value has no inventory of its own, and the most popular media owner creates no content. But what about the role of regulation in this brave new world? We take a look at the rivals, taxi companies and private hire transport companies (in particular Uber), to assess the need for regulation and the impact of regulation on these two contenders. Our research examines the effects of said regulation on service quality and safety, correlated with consumer opinion data. The impact of non-regulatory incentives on the two seemingly-opposed business models is discussed, thus making the logical case for increased deregulation of both taxis and private hire companies. Opening the way to innovative companies and innovative new business models, allowing them to change the world is our gateway to growth, prosperity and sustainability.
Leadership in Higher Education – coping with AI and the turbulence of our times
Authors: Nicolae Mariana , Nicolae Elena E. 
Published: June 2018

Abstract
Today’s world is clearly fractured whether we are looking at it through economic, political, cultural or educational lenses. This is in no way something new. The world has always been in this state, but the speed with which it reacted to real or perceived threats and tried to change accordingly was barely perceivable and, therefore, easier to adopt and adapt to. Today those changes happen with incredible speed and our reactions to them may not be informed or educated and are usually taken by leaders who are, at best, controversial and at worst obviously partial to their own, petty interests against the greater public good they vowed to serve. What can higher education do in such a world? Artificial intelligence (AI) is making huge progress and, although education at all levels is lagging behind in meaningfully adopting AI and working with it, the educational system is expected to react to a world divided by the fear of AI using big data, claiming jobs, and ushering in the era of loss of human supremacy or by the glorification of AI which is only a tool, fast developing indeed, but permanently controlled by human intelligence. Even if that human intelligence is concentrated into fewer and fewer human decision makers thus contributing to the already huge gap of inequality existing in today’s world. The present paper will explore issues related to the way in which the leadership of higher education chooses to handle today’s challenges and will use the home university of the authors to illustrate what happens in Romanian universities. The discussion will be informed by the authors’ own experience in the higher education system as well as by an analysis of various discourses and narratives belonging to different stakeholders, discussing those issues in various inter/national media. The paper will offer some recommendations.
The Globalization in the actual Context of the European Union Economy
Authors: Păunică Mihai , Manole Alexandru , Motofei Cătălina , Tănase Gabriela Lidia 
Published: June 2018

Abstract
In this paper, the authors aim to realize an in-depth analysis of the current characteristics of the globalization phenomenon from the viewpoint of the European Union and Romanian economy. The study will pursue some of the globalization indicators published by Eurostat, their status and a multidimensional perspective on their evolution. Namely, the foreign trade, the foreign direct investments, the employment, value added shall be subjected to analysis. The authors will apply statistical and econometric techniques to outline the behavior of economic globalization, depending on the values and dynamics of the support indicators. The structural and dynamic evaluation shall consider the main aspect of the multi-dimensional perspective, the geographical dimension. Both statistical and econometric tools applied lead to a set of conclusions, either general or subject-oriented, which show the present impact and trends of globalization in the European Union and Romanian economic activity. The research question was focused on how strong is the influence of globalization indicators on the economic growth for European Union and Romania. The results outline the behavior of the globalization indicators in the recent period, with focus on the effects of the economic crisis. The main indicators considered were the net export, import, export and the foreign direct investments, and their impact of the Gross Domestic Product is also revealed.