bluuebunny/crossref_metadata_2025_split huggingface dataset:
La revue INRA Productions Animales dans la production scientifique en élevage et sciences animales
Authors: BAUMONT René , GIRARD Agnès 
Published: October 2019

Depuis 30 ans, la revue INRA Productions Animales publie principalement des articles de synthèse sur tous les sujets concernant les productions animales à destination d’un large public d’utilisateurs des résultats de la recherche. À partir de la base de données « Web of Science ™ » (WOS) et dans le périmètre limité à la catégorie « Agriculture, dairy and animal sciences » dans laquelle la revue est indexée depuis 1997, cet article propose une analyse du positionnement de la revue dans la littérature scientifique internationale, européenne et de l’INRA. Dans une production scientifique multipliée par deux entre 1997 et 2017 dans cette WOS catégorie (9000 articles en 2017), le nombre d’articles publiés chaque année par l’INRA (environ 250) et par la revue (entre 30 et 35) est stable. La France est le 7ème pays contributeur derrière les USA, l’Inde, la Chine, le Brésil, l’Allemagne et le Canada. L’analyse lexicale de l’ensemble des références du WOS montre une grande stabilité des termes les plus fréquemment utilisés qui restent dominés par les problématiques de production. En revanche, l’analyse de l’évolution des publications montre clairement l’émergence et la montée en puissance des recherches menées sur les systèmes d’élevage, le bien-être animal et la sélection génomique, à la fois en Europe et à l’INRA. Au final, les recherches conduites par l’INRA dans le domaine des productions animales, et en particulier celles diffusées par la revue INRA Productions Animales, sont au diapason des recherches conduites à l’échelle européenne.
Risk of Arterial Injury During Hip Internal Fixation
Authors: Jaipurwala Rizwan , Galea Michael , Hardidge Andrew 
Published: October 2019

Background:
Injury to femoral arterial vessels is a risk with internal fixation of the hip. Understanding the anatomy of proximate vessels, particularly medial vessels not directly visualized, may reduce intraoperative and postoperative complications.

Methods:
We analyzed 47 patients (29 men and 18 women) using a computed tomographic (CT) angiogram of the lower limbs. The mean age of our patients was 69 years (range, 46 to 88 years). The distance from the tip of the greater trochanter to the profunda femoris and its perforators within 5 mm of the medial femoral shaft was measured along the length of the expected placement of typical dynamic hip screw constructs and other proximal femoral fracture fixation methods.

Results:
All patients were found to have 2 perforator vessels within 5 mm of the medial femoral shaft along the line of dynamic hip screw insertion (up to 200 mm from the tip of the greater trochanter). The first perforator was found at a mean distance of 112.6 mm (median, 110 mm) in women and at 123.4 mm (median, 122 mm) in men (p = 0.0066) from the tip of the greater trochanter. The second perforator appeared at a mean distance of 159.7 mm (median, 159 mm) in women and 178.9 mm (median, 180 mm) in men (p = 0.0028) from the tip of the greater trochanter.

Conclusions:
Surgeons should be aware of the presence of 2 arteries within 5 mm of the medial femoral shaft during femoral internal fixation procedures. We suggest avoiding the overdrilling of the medial cortex and the insertion of overlong screws along the femoral shaft from 110 to 120 mm in women and 120 to 130 mm in men (as measured from the tip of the greater trochanter) to prevent vascular injury during proximal femoral fracture fixation.

Clinical Relevance:
This article can assist orthopaedic surgeons in planning for procedures involving internal fixation of the hip and may reduce vascular complications from such procedures.
Outcomes of Total Ankle Arthroplasty in Ankles with >20° of Coronal Plane Deformity
Authors: Lee Gun-Woo , Lee Keun-Bae 
Published: October 2019

Background:
A preoperative severe coronal plane deformity of >20° has been considered a contraindication for total ankle arthroplasty. We aimed to evaluate whether outcomes of total ankle arthroplasty in ankles with severe coronal plane deformity (20° to 35° of varus or valgus) are comparable with those with moderate deformity (5° to 15° of varus or valgus).

Methods:
A total of 148 consecutive ankles (142 patients) that underwent primary total ankle arthroplasty using the HINTEGRA prosthesis were included. The overall mean follow-up duration was 74 months (range, 24 to 160 months). We divided all patients into 2 groups according to the preoperative coronal plane tibiotalar angle: the severe group (36 patients, 41 ankles) and the moderate group (106 patients, 107 ankles). Clinical and radiographic outcomes were analyzed for intergroup differences, and multivariable regression was used to adjust for baseline characteristics. Patients in each group showed similar characteristics in mean age, sex, mean body mass index, and median follow-up duration.

Results:
At a mean follow-up of 74 months, we found no significant intergroup difference in the Ankle Osteoarthritis Scale pain and disability score, American Orthopaedic Foot & Ankle Society ankle-hindfoot score, Short Form-36 Physical Component Summary score, visual analog scale pain score, or ankle range of motion (p > 0.05). However, the final tibiotalar angle, talar tilt angle, and number of outliers were greater in the severe group (p < 0.05). Complication rates did not show a significant difference between the 2 groups (p > 0.05). The overall survival probability of the implant was 91.3% (92.3% in the severe group and 90.7% in the moderate group) (p = 0.354).

Conclusions:
Total ankle arthroplasty in ankles with preoperative severe coronal plane deformity showed satisfactory and comparable clinical outcomes without increasing complication rates relative to those with moderate deformity in the intermediate-term follow-up. Our results suggested that total ankle arthroplasty may be considered in ankles with deformity of >20°.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Ethics of Opioid Prescriber Regulations
Authors: Lajam Claudette M. , Cenname John , Hutzler Lorraine H. , Bosco Joseph A. 
Published: October 2019

Background:
Opioid addiction affects patients of every race, sex, and socioeconomic status. Overprescribing is a known cause of the opioid crisis. Various agencies have implemented requirements and programs to combat practitioner overprescribing; however, there can be adverse ethical consequences when regulations are used to influence physician behavior. We aimed to explore the ethical aspects of some of these interventions.

Methods:
We reviewed various interventions for opioid prescribing through the lens of ethical inquiry. Specifically, we evaluated (1) requirements for educational programs for prescribers and patients, (2) prescription monitoring programs, (3) prescription limits, (4) development of condition-specific pain management guidelines, (5) increased utilization of naloxone, and (6) opioid disposal programs. We also evaluated patient satisfaction survey questions relating to pain.

Results:
The present analysis demonstrated that the following regulatory interventions are ethically sound: requirements for educational programs for prescribers and patients, robust prescription monitoring programs that cross state lines, increased prescribing of naloxone for at-risk patients, development of condition-specific pain management guidelines, improvement of opioid disposal programs, and elimination of pain-control questions from patient satisfaction surveys. However, implementation of strict prescribing limits without accommodation for procedure and patient characteristics may have negative ethical consequences.

Conclusions:
Although the importance of addressing the current opioid crisis cannot be understated, as surgeons, we must examine ethical implications of any new regulations that affect musculoskeletal patient care.
Long-Term Results of Total Knee Arthroplasty with Contemporary Distal Femoral Replacement
Authors: Wyles Cody C. , Tibbo Meagan E. , Yuan Brandon J. , Trousdale Robert T. , Berry Daniel J. , Abdel Matthew P. 
Published: October 2019

Background:
Distal femoral replacement (DFR) is a salvage option for complex primary and revision total knee arthroplasty (TKA). Although excellent immediate fixation and weight-bearing are achieved, there is a paucity of data on long-term outcomes of TKA with DFR. The purpose of the present study was to determine implant survivorship, clinical outcomes, and radiographic results of TKAs with contemporary DFR components in a large series.

Methods:
We identified 144 consecutive TKAs performed with DFR for non-oncologic indications from 2000 to 2015 at a single academic institution. Indications for the index DFR included 66 (46%) for native (n = 11) or periprosthetic (n = 55) femoral fracture, 40 (28%) for staged treatment of periprosthetic joint infection, 28 (19%) for aseptic TKA loosening, and 10 (7%) for other indications. Porous metal cones were used to augment femoral fixation in 28 patients (19%) and tibial fixation in 38 patients (26%). Outcomes included cumulative incidence of revision and reoperation (utilizing a competing risk model), Knee Society scores, and radiographic results. The mean age at the time of index DFR was 72 years, and 65% of patients were female. The mean follow-up was 5 years (range, 2 to 13 years) for the 111 patients who did not undergo revision, had not died, and were not lost to follow-up.

Results:
The 10-year cumulative incidences of revision for aseptic loosening, all-cause revision, and any reoperation were 17.0%, 27.5%, and 46.3%, respectively. There was an increased risk of reoperation in patients who underwent index DFR for aseptic TKA loosening (hazard ratio [HR], 2.30; p = 0.026) or periprosthetic joint infection (HR, 2.18; p = 0.022) compared with periprosthetic or native femoral fractures. However, there was no difference in risk of revision for aseptic loosening or all-cause revision based on the original operative indication. The mean Knee Society score increased from 45 preoperatively to 71 at the time of the latest follow-up (p < 0.001). Radiographic loosening was observed in 8 unrevised DFRs (7%). There were 7 above-the-knee amputations performed at the time of the final follow-up, all for intractable periprosthetic joint infection.

Conclusions:
TKAs with contemporary DFR had high 10-year cumulative incidences of both revision and reoperation, underscoring the salvage nature of this procedure as a final reconstructive option. Most patients experienced substantial clinical improvements with this end-stage revision procedure.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Complications and Long-Term Outcomes of Open Reduction and Plate Fixation of Proximal Humeral Fractures
Authors: Robinson C. Michael , Stirling Paul H.C. , Goudie Ewan B. , MacDonald Deborah J. , Strelzow Jason A. 
Published: October 2019

Background:
The optimal treatment of complex proximal humeral fractures in adults remains controversial. We evaluated the risk of complications and the long-term outcomes in patients with a severely displaced fracture or a fracture-dislocation of the proximal part of the humerus treated with open reduction and plate fixation (ORIF).

Methods:
Between 1995 and 2012, 5,897 consecutive patients with a proximal humeral fracture were referred to a specialist shoulder clinic for surgical assessment. Indications for surgery included anterior or posterior fracture-dislocation, substantial tuberosity involvement with >1 cm of displacement in a Neer 3 or 4-part fracture configuration, disengagement of the head from the shaft, or severe varus or valgus deformity of the head. All patients who met the surgical criteria and had been followed for 2 years were included, and standardized clinical and radiographic assessments of outcomes were performed. At a median of 10.8 years (range, 5 to 22 years) after ORIF, all surviving cognitively intact patients completed a patient-reported questionnaire assessing functional outcomes and satisfaction.

Results:
Three hundred and sixty-eight patients (6.2%) met the inclusion criteria and had the appropriate follow-up. The study population had a high rate of complex fracture configurations; 77.2% had tuberosity involvement, 54.1% had complete head-shaft disengagement, and 44.0% had a dislocated head. Eighty-seven patients (23.6%) had postoperative stiffness, 25 (6.8%) had fixation failure/nonunion, and 16 (4.3%) had late osteonecrosis/posttraumatic osteoarthritis; these complications were the reason for the majority of the reoperations in the cohort. The survivorship until any reoperation was 74% at 10 years, but when reoperations for stiffness were excluded, the survivorship was 90% during the same time period. The patients’ mean levels of pain, function, and satisfaction with treatment were good to excellent.

Conclusions:
Our results support the use of primary ORIF in medically fit patients with a severely displaced fracture or a fracture-dislocation of the proximal part of the humerus in centers where the expertise to carry out such treatment exists.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Topics, Skills, and Cases for an Undergraduate Musculoskeletal Curriculum in Southern Africa
Authors: Held Michael F.G. , Laubscher Maritz , Graham Simon M. , Kruger Nicholas , Njisane Phinda , Njisane Vela , Dunn Robert N. ,   on behalf of the Learning Innovation via Orthopaedic Networks (LION) Group
Published: October 2019

Background:
Most patients with orthopaedic pathology in low to middle-income countries are treated by nonspecialists. A curriculum to prepare undergraduate medical students for this duty should reflect the local pathology and skills that are required to manage patients in a resource-restricted environment. The aim of this study was to establish and prioritize a list of core orthopaedic-related knowledge topics, clinical cases, and skills that are relevant to medical students in southern Africa and areas with a similar clinical context.

Methods:
A modified Delphi consensus study was conducted with 3 interactive iterative rounds of communication and prioritization of items by experts from Africa, Europe, and North America. Preferred priorities were selected but were limited to 50% of all of the possible items. Percent agreement of ≥75% was defined as consensus on each of these items.

Results:
Most of the 43 experts who participated were orthopaedic surgeons from 7 different countries in southern Africa, but 28% were general practitioners or doctors working in primary or secondary-level facilities. Experts prioritized cases such as patients with multiple injuries, a limping child, and orthopaedic emergencies. Prioritized skills were manipulation and immobilization of dislocations and fractures. The most important knowledge topics included orthopaedic infections, the treatment of common fractures and dislocations, any red flags alerting to specialist referral, and back pain. Surgical skills for the treatment of urgent care conditions were included by some experts who saw a specific need in their clinical practice, but these were ranked lower.

Conclusions:
A wide geographic, academic, and expertise-specific footprint of experts informed this international consensus through their various clinical and academic circumstances. Knowledge topics, skills, and cases concerning orthopaedic trauma and infection were prioritized by the highest percent agreement. Acute primary care for fractures and dislocations ranked high. Furthermore, the diagnosis and the treatment of conditions not requiring specialist referral were prioritized. This study can inform national curricula in southern Africa and assist in the allocation of student clinical rotations.
Design Aspects of Complex Toe-to-Heel Flooding
Authors: Algarhy Ahmed , Soliman Mohamed , Turta Alex 
Published: October 2019

Abstract
Complex Toe-to-Heel Flooding (CTTHF) is a short distance flooding technique developed by the authors for sandstone formations. CTTHF applied on horizontal wells and requires at least one barrier and injector hydraulic fracture, also it requires at least one method to control early water production. This paper discusses the design aspects of the CTTHF including the design of barrier fracture, injector fracture, and the produced water control methods. Technical and economical evaluation to rank different design setups is performed and presented.
Advanced commercial reservoir simulator with hydraulic fracturing module was used to simulate different CTTHF setups and reservoir conditions to set the reservoir selection criteria and proper design methodology. In this study, Toe-to-Heel Waterflooding was considered the base case. Sensitivity studies for barrier fracture and injector design has been achieved and presented. Moreover, a sensitivity studies for hydraulic fractures spacing, number of barrier fractures, batch injection scheduling and changing packer location have been performed.
When CTTHF is applied in high permeable sandstone formation, early water production is expected, except produced water control method is used. This study states the feasibility conditions for each proposed produced water control technique. Also, a methodology for candidate reservoir selection, design of barrier and injector fractures is developed and presented. There are multiple fluid systems can be used to create the barrier to seal a pre-determined zone. CTTHF is better reservoir management approach.
The novelty of the CTTHF is giving multiple options for produced water control that maximizes the produced oil and minimizes the water production. CTTHF's produced water control can make some reservoirs economic to produce.
Robust Estimation of Arps Decline Parameters Using Regularizing Priors
Authors: Ravikumar Arjun , Lee John 
Published: October 2019

Abstract
Decline curve analysis is widely used in industry to perform production forecasting and to estimate reserves volumes. A useful technique in verifying the validity of a decline model is to estimate the Arps decline parameters, the loss ratio and the b-factor, with respect to time. This is used to check the model fit and to determine the flow regimes under which the reservoir produces. Existing methods to estimate the b-factor are heavily impacted by noise in production data. In this work, we introduce a new method to estimate the Arps decline parameters.
We treat the loss ratio and the b-factor over time as parameters to be estimated in a Bayesian framework. We include prior information on the parameters in the model. This serves to regularize the solution and prevent noise in the data from being amplified. We then fit the parameters to the model using Markov chain Monte Carlo methods to obtain probability distributions of the parameters. These distributions characterize the uncertainty in the parameters being estimated. We then compare our method with existing methods using simulated and field data.
We show that our method produces smooth loss ratio and b-factor estimates over time. Estimates using the three-point derivative method are not matched with data, and results in biased estimates of the Arps parameters. This can lead to misleading fits in decline curve analysis and unreliable estimates of reserves. We show that our technique helps in identification of end of linear flow and start of boundary dominated flow. We use our method on simulated data, with and without noise. Finally, we demonstrate the validity of our method on field cases.
Fitting a decline curve using the loss ratio and b-factor plots is a powerful technique that can highlight important features in the data and the possible points of failure of a model. Calculating these plots using the Bourdet three-point derivative induces bias and magnifies noise. Our analysis ensures that this estimation is robust and repeatable by adding prior information on the parameters to the model and by calibrating the estimates to the data.
Effect of Pore Size Heterogeneity on Hydrocarbon Fluid Distribution and Transport in Nanometer-Sized Porous Media
Authors: Zhang Kaiyi , Du Fengshuang , Nojabaei Bahareh 
Published: October 2019

Abstract
In this paper, we investigate the effect of pore size heterogeneity on multicomponent multiphase hydrocarbon fluid composition distribution and its subsequent influence on mass transfer through shale nano-pores. We use a compositional simulation model with modified flash calculation, which considers the effect of large gas-oil capillary pressure on phase behavior. We consider different average pore sizes for different segments of the computational domain and investigate the effect of the resulting heterogeneity on phase and composition distributions, and production. A two dimensional formulation is considered here for the application of matrix-fracture cross mass transfer. Note that the rock matrix can also consist of different regions with different average pore sizes. Both convection and molecular diffusion terms are included in the mass balance equations, while different reservoir fluids such as Bakken and Marcellus are considered. The simulation results show that since oil and gas phase compositions depend on the pore size, there is a concentration gradient between the two adjacent pores with different sizes. Considering that shale permeability is small, we expect the mass transfer between two sections of the reservoir/core with two distinct average pore sizes to be diffusion-dominated. This observation implies that there can be a selective matrix-fracture component mass transfer during both primary production and gas injection EOR as a result of confinement-dependent phase behavior. Therefore, molecular diffusion term should be always included in the mass transfer equations, for both primary and gas injection EOR simulation of heterogeneous shale reservoirs.