bluuebunny/crossref_metadata_2025_split huggingface dataset:
A critical review of the Ganges Water Sharing arrangement
Authors: Rahman Kazi Saidur , Islam Zahidul , Navera Umme Kulsum , Ludwig Fulco 
Published: February 2019

AbstractThe 1996 Ganges Water Sharing Treaty was an important breakthrough in solving disputes over sharing Ganges water between India and Bangladesh. This study evaluates cooperation reflected in the Treaty by performing a quantitative analysis on available water sharing data. The study recognized that inaccurate projection of future flow and the obligation of allocating guaranteed 991 m3/s flows perpetuate the ongoing water sharing conflicts. The provision of guaranteed minimal flow alternately to India and Bangladesh during critical periods leads to frequent occurrences of low-flow events. Results indicated that the Treaty underestimated the impact of climate variability and possibly increasing upstream water abstraction. Statistical analysis of the post-Treaty data (1997–2016) also indicated that 65% of the time Bangladesh did not receive its guaranteed share during critical dry periods with high water demand. It is advised to project the reliable water availability using a combination of modelling and improved observation of river flows. In addition, the condition of minimum guaranteed share should be removed to reduce the frequency of low-flow events in future. Although our analyses show a number of weaknesses, the Treaty could still enhance the future regional cooperation if some adjustments are made to the current terms and conditions.
Cytotoxic Activity of Methoxy-4’amino Chalcone Derivatives Against Leukemia Cell Lines
Authors: Novilla Arina , Mustofa Mustofa , Astuti Indwiani , Jumina Jumina , Suwito Hery 
Published: March 2019

Background: Chemotherapy is a common treatment for leukemia as well as in other cancer treatment. The lack of tumor selectivity and development of multi-drug resistance by chemotherapy caused the development of new strategy in cancer treatment become a pressing need. This study was performed to evaluate the anticancer activity and selectivity of seven derivatives of chalcones against K562 and HL-60 leukemia cell lines. Materials and Methods: The cytotoxicity of chalcone’s seven derivatives (compound 1-7) was tested by using MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxyme-thoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) method. The percentage of cell mortality data was calculated then the IC50 was analyzed using probit analysis (SPSS 17). The selectivity index (SI) then calculated from IC50 ratio of normal lymphocyte cells and cancerous cells line (HL-60 and K562).Results: The IC50 of almost all seven tested compounds were lower in HL-60 cell lines than K562 cell lines, except for Compound 7. The number and position of methoxy groups in chalcone derivatives influenced the anticancer and cancer selectivity of chalcone derivatives.Conclusion: The results revealed that the number and position of methoxy groups in chalcone derivatives influenced the anticancer and cancer selectivity of chalcone derivatives.Keywords: anticancer, chalcone derivatives, methoxy-4’-amino chalcone, leukemia, cytotoxic, selectivity
Efficacy and Toxicity of Addition of Bevacizumab to Chemotherapy in Patients with Metastatic Colorectal Cancer
Authors: Ruan Wen-Cong , Che Yue-Ping , Ding Li , Li Hai-Feng 
Published: February 2019

Background:
Pre-treated patients with first-line treatment can be offered a second
treatment with the aim of improving their poor clinical prognosis. The therapy of metastatic
colorectal cancer (CRC) patients who did not respond to first-line therapy has limited treatment
options. Recently, many studies have paid much attention to the efficacy of bevacizumab as an
adjuvant treatment for metastatic colorectal cancer.

Objectives:
We aimed to evaluate the efficacy and toxicity of bevacizumab plus chemotherapy
compared with bevacizumab-naive based chemotherapy as second-line treatment in people with
metastatic CRC.

Methods:
Electronic databases were searched for eligible studies updated to March 2018.
Randomized-controlled trials comparing addition of bevacizumab to chemotherapy without
bevacizumab in MCRC patients were included, of which, the main interesting results were the
efficacy and safety profiles of the addition of bevacizumab in patients with MCRC as second-line
therapy.

Result:
Five trials were eligible in the meta-analysis. Patients who received the combined
bevacizumab and chemotherapy treatment in MCRC as second-line therapy showed a longer overall
survival (OS) (OR=0.80,95%CI=0.72-0.89, P<0.0001) and progression-free survival (PFS)
(OR=0.69,95%CI=0.61-0.77, P<0.00001). In addition, there was no significant difference in
objective response rate (ORR) (RR=1.36,95%CI=0.82-2.24, P=0.23) or severe adverse event (SAE)
(RR=1.02,95%CI=0.88-1.19, P=0.78) between bevacizumab-based chemotherapy and bevacizumabnaive
based chemotherapy.

Conclusion:
Our results suggest that the addition of bevacizumab to the chemotherapy therapy
could be an efficient and safe treatment option for patients with metastatic colorectal cancer as
second-line therapy and without increasing the risk of an adverse event.
A Novel Approach of Solving Output Displacement of Compliant Mechanism Based on Integration Method
Authors: Gong Jinliang , Li Xiang , Zhang Yanfei , Mostafa Kazi 
Published: February 2019

Background:
Micro-positioning platform is a device with high accuracy of positioning and
a certain range of motion. Accuracy of the micro-positioning mechanism is ensured by using a flexible
hinge to replace the traditional motion pair.

Objective:
A two-dimensional micro-positioning platform is proposed in this study. It is necessary to
find out how the geometric parameters affect the output displacement of the amplification structure
component. Thus, this paper aims to build up the relation model of stiffness and geometric parameters.

Method:
A novel method for building the relational model of parameters and output displacement is
introduced on the basis of the superposition principle of small deformation and the principle of deflection.
Firstly, the amplification structure is divided into different units according to the section shape
and force. Secondly, the parametric model of integral deflection curve of the amplification structure is
solved. The method is based on the flexibility matrix of the flexible hinge unit and the differential
equation of the deflection curve of the rectangular unit. Finally, the parametric model of output displacement
is established by using the integral deflection curve equation and geometric relationship between
adjacent deformations of the compliant structure.

Result:
It is shown that the output displacements by analysis method are close to the results achieved
by the ANSYS software, with a maximal difference of 15.3%. The reason is that the integral deflection
curve is not smooth at some special points, which is verified by finite element analysis.
A Clinical Care Monitoring and Data Collection Tool (H3 Tracker) to Assess Uptake and Engagement in Mental Health Care Services in a Community-Based Pediatric Integrated Care Model: Longitudinal Cohort Study
Authors: McCreary Michael , Arevian Armen C , Brady Madeline , Mosqueda Chichits Ana E , Zhang Lily , Tang Lingqi , Zima Bonnie 
Published: March 2019

Background
National recommendations for pediatric integrated care models include improved capacity for care coordination and communication across primary care and specialty mental health providers using technology, yet few practical, short-term solutions are available for low-resource, community-based pediatric integrated care clinics.

Objective
The goal of the paper is to describe the development and features of a Web-based tool designed for program evaluation and clinician monitoring of embedded pediatric mental health care using a community-partnered approach. In addition, a longitudinal study design was used to assess the implementation of the tool in program evaluation, including clinical monitoring and data collection.

Methods
Biweekly meetings of the partnered evaluation team (clinic, academic, and funding partners) were convened over the course of 12 months to specify tool features using a participatory framework, followed by usability testing and further refinement during implementation.

Results
A data collection tool was developed to collect clinic population characteristics as well as collect and display patient mental health outcomes and clinical care services from 277 eligible caregiver/child participants. Despite outreach, there was little uptake of the tool by either the behavioral health team or primary care provider.

Conclusions
Development of the H3 Tracker (Healthy Minds, Healthy Children, Healthy Chicago Tracker) in two community-based pediatric clinics with embedded mental health teams serving predominantly minority children is feasible and promising for on-site program evaluation data collection. Future research is needed to understand ways to improve clinic integration and examine whether promotion of primary care/mental health communication drives sustained use.

Trial Registration
ClinicalTrials.gov NCT02699814; https://clinicaltrials.gov/ct2/show/NCT02699814 (Archived by WebCite at http://www.webcitation.org/772pV5rWW)
El derecho de huelga: ¿Un derecho fundamental excepcional?
Authors: Ambesi Leonardo J. 
Published: March 2019

<p>Como consecuencia de las limitaciones que encuentran las personas con discapacidad para el acceso al empleo ordinario, el autoempleo y el emprendimiento constituyen la alternativa por la que se opta, a fin de incorporarse al área ocupacional productiva. Se analiza en este trabajo las principales iniciativas en España dirigidas al fomento del emprendimiento y se aportan las principales actuaciones y resultados obtenidos por el Grupo de Investigación en cuanto al fomento del emprendimiento de las personas con discapacidad.</p><div> </div>
Pengaruh Pendidikan Kesehatan Menstrual Hygiene (PMH) Terhadap Sikap Remaja Putri dalam Menjaga Kebersihan Diri Selama Menstruasi
Authors: Meinarisa Meinarisa 
Published: March 2019

<p><em>WHO reported that the women mortality and morbidity due to reproductive system disorders increased in last decade. One of the cause the reproductive tract infection is unhygiene during menstruation. This study aims to examine the effect of Menstrual Hygiene (PMH) health education on the attitudes of adolescent girls in maintaining personal hygiene during menstruation and this research is a quasi-experiment with pre-test and post-test with control group. 98 adolescent girls from junior high school has participate in this research, 48 respondents in intervention group have been given the Menstrual Hygiene Education through lectures, direct demonstration using phantom, booklet and self-report filling during menstruation. The questionnaire that used is Adolescent Menstrual Attitude Questionnaire to measure the attitude of adolescent girls. The results showed Menstrual Hygiene Education (MHE) there was influence of adolescent girls in monitoring personal hygiene during menstruation p=0,001 (95% CI 223,38 – 234,17). MHE improved the attitude of adolescent girls and helps the adolescents to understand personal hygiene during menstruation. This research recommend MHE can use by nurses for health education in school health unit.</em></p><p>Angka kematian dan kecacatan pada wanita karena gangguan sistem reproduksi semakin meningkat. Salah satu penyebabnya adalah infeksi organ reproduksi dan infeksi organ perkemihan. Penyakit infeksi disistem reproduksi dapat disebabkan karena kebersihan yang kurang dari wanita saat menstruasi. Penelitian ini bertujuan menguji pengaruh Pendidikan kesehatan Menstrual Hygiene (PMH) terhadap sikap remaja putri dalam menjaga kebersihan diri selama menstruasi dan merupakan penelitian quasi-experiment dengan pretest and posttest with control group. Sejumlah 98 remaja putri dari Sekolah Menengah Pertama (SMP) N 24 dan 3 kota Jambi berpartisipasi dalam penelitian, 48 orang pada kelompok intervensi diberikan Pendidikan kesehatan Menstrual Hygiene (PMH) melalui ceramah, demostrasi langsung menggunakan phantom dan pemberian booklet. Serta pengisian self-report selama menstruasi. Kuesioner yang digunakan adalah Adolescent Menstrual Attitude Questionnaire untuk mengukur sikap remaja putri. Hasil penelitian menunjukkan ada pengaruh PMH terhadap sikap remaja putri dalam menjaga kebersihan diri selama menstruasi p=0,001 (95% CI 223,38 – 234,17). PMH meningkatkan sikap remaja putri dan membantu remaja untuk memahami kebersihan diri selama menstruasi. Penelitian ini merekomendasikan PMH digunakan oleh perawat dalam penyuluhan kesehatan di Unit Kesehatan Sekolah (UKS).</p>
Processing The Difference In Spanish-Language Media In Morocco
Authors: Jablonka Frank - 
Published: March 2019

Spanish-language media in Morocco represent currently an almost unexplored field of research. The present contribution is centred on some aspects of postcolonial (and even, in a large sense, colonial, since we take into account online documents from the Spanish presidios on the Mediterranean coast as well) discours formations in the Spanish-language blogosphere. While discourses focused on postcolonial topics in French blogs have already been analyzed (Torterat, forthcoming), investigations of a similar orientation do not seem to have been carried out on our research object.
Listening Metacognitive Awareness
Authors: LEE Hsin-I , Mukhlynina Irina 
Published: March 2019

Closely connected with other language skills, listening plays an essential role in language acquisition that is why perception of authentic speech is one of the most important aspects of language teaching and development of learners listening strategies is substantial in language teaching. In this paper, we examine French and English literature on this topic. We conduct our study by means of a questionnaire among 21 Chinese and 21 Russian university students who achieved at least Intermediate level in French L2. The data analysis allows us to show how difficult listening is for the students and also to demonstrate which metacognitive listening strategies they use. Finally, we draw some trends in L2 listening among interviewed Chinese and Russian students.
Conceptualization of Persian Relative Structure in Cognitive Grammar
Authors: Khoshbakht Sahel , Golfam Arsalan , Kord Zaferanloo Kamboozia Alie , Aghagolzadeh Ferdows 
Published: March 2019

Abstract
In the cognitive approach to linguistics, language is considered as a part of the cognitive system which mirrors the conceptual organization as well as the world within the speakers' mind. According to this view, the outside world experience is reflected in the language structure and language forms. This modern approach includes a variety of principles, perspectives, assumptions and models, among which the Cognitive Grammar Model is recognized as the most noticeable one. This grammar considers a symbolic nature for a language which symbolizes the meaning and thought. On the other hand, relativization as a notion in every individual's mind and cognition is considered as a universal manifested in all languages. Thus, the present research tries to clarify the conceptualization and symbolization of Persian relative structure from the cognitive point of view and by the use of cognitive means. It, also studies different types of relative structures in Persian, on the basis of Langacker (2008) model and differentiates the restrictive and non-restrictive relative clauses in Persian. The methodology used in the analysis of this research is the descriptive-analytical methodology. For the data collection, the corpus methodology is used and examples of Persian relative structures are studied. The present research findings show that Persian conceptualization of the relative structures can be clarified in the cognitive approach and Persian relative structures can be studied on the basis of Langacker model.
Supplement to the Collatz Conjecture
Authors: Nikolaychuk Anatoliy 
Published: March 2019

For any natural number was created the supplement sequence, that is convergent together with the original sequence. The parameter - index was defined, that is the same tor both sequences. This new method provides the following results:

All natural numbers were distributed into different classes according to the corresponding indexes;
The analytic formulas ( not by computer performed routine calculations) were produced, the formulas for groups of consecutive natural numbers of different lengths, having the same index;
The new algorithm to find index for any natural number was constructed and proved.
Some modifications on RCAM for getting accurate closed-form approximate solutions of Duffing- and Lienard-type equations
Authors: Das Prakash Kumar , Singh Debabrata , Panja Madan Mohan 
Published: March 2019

In this work, authors propose some modifications Adomian decomposition method to get some accurate closed form approximate or exact solutions of Duffing- and Li´enard-type nonlinear ordinary differential equations.Results obtained by the revised scheme have been exploited subsequently to derive constraints among parameters to get the solutions to be bounded. The present scheme appears to be efficient and may be regarded as the confluence of apparently different methods for getting exact solutions for a variety of nonlinear ordinary differential equations appearing as mathematical models in several physical processes.
Gestão da marca
Authors: Pivatto Luana Schneider , Ternus Carline 
Published: March 2019

O presente artigo tem como objetivo mapear, a partir de um levantamento bibliométrico, a área de gestão de marca na base de dados Spell, analisando quem são os principais autores, Instituições de Ensino e periódicos que publicam sobre o tema. A metodologia utilizada constitui-se de um estudo descritivo e exploratório com a análise dos 50 artigos encontrados foi realizada na base de dados do site Spell, em fevereiro de 2017, e levou às seguintes descobertas: predominância de artigos com métodos qualitativos; a maior parte dos artigos foi elaborada por dois ou três autores; não houve número expressivo de publicações por autor sobre o tema; a Universidade Federal do Rio Grande do Sul – UFRGS é a IES de destaque na produção científica; maior parte dos artigos da amostra foram produzidos no ano de 2015; a Revista Brasileira de Marketing é o periódico destaque em publicações; o Valor de Marca é o construto mais utilizado, relacionado com o tema Gestão de Marca; apenas 01 artigo dos 50 da amostra possui instrumento de coleta de dados. A partir do estudo presente, conclui-se que, a criação da gestão de marca, portanto, é a principal estratégia de negócio, utilizada como componente chave do marketing empresarial, aliada aos desejos, necessidades e à promessa de satisfação, contribuindo expressivamente para os fatores essenciais da relação de interdependência marca-consumidor.
Palavras-chave: Marketing. Gestão de marca. Estudo Bibliométrico.
A inclusão e retenção da pessoa com deficiência nas organizações
Authors: Favero Marcela Bortotti , Silva Elza Aparecida da Mata 
Published: March 2019

O objetivo desta pesquisa foi a verificação e análise dos procedimentos dos recrutadores das organizações para o cumprimento efetivo da Lei de Cotas, bem como estratégias para anúncio, recrutamento e seleção de profissionais PcD (Pessoa com Deficiência), e as dificuldades encontradas nesse processo. O presente artigo foi realizado na cidade de Maringá-PR e região, com 26 empresas de diversos ramos de atividades e que possuem mais 100 colaboradores. Essa pesquisa se constituiu em um estudo descritivo quantitativo, realizado no período de Outubro à Novembro de 2017. O instrumento utilizado na pesquisa, foi um questionário com 11 itens que abordaram quais as formas de anúncio, recrutamento, seleção e retenção de profissionais PCD, bem como as dificuldades encontradas. Através da análise dos resultados obtidos, a grande maioria das empresas atualmente que necessitam ter profissionais PcD em seu quadro de colaboradores, têm encontrado dificuldades em cumprir a legislação, devido à falta desses profissionais qualificados no mercado de trabalho, bem como a falta de adaptação dos mesmos à cultura da empresa.
Palavras chaves: Cotas. Inclusão Social. Pessoa com deficiência.
Utilização de informações contábeis e gerenciais por parte dos empresários de micros e pequenas empresas
Authors: Witt Cleonice , Pletsch Caroline Sulzbach , Hein Nelson , Kroenke Adriana 
Published: March 2019

O estudo tem como objetivo analisar as informações contábeis e gerenciais utilizadas pelos gestores de micros e pequenas empresas. Trata-se de um estudo descritivo, de levantamento e quantitativo. Compõe a amostra do estudo 73 micros e pequenas empresas sediadas no Vale do Itajaí/SC. Os dados foram coletados mediante aplicação de questionário com questões de múltipla escolha e escala Likert, sendo o tipo de amostragem por acessibilidade. Para análise de dados aplicou-se análise de correspondências múltiplas (ANACOR) utilizando o software LHStat 4.5. Os resultados indicam que o tempo de atuação da maioria das empresas é de 6 a 10 anos, atuam no comércio e possuem até 5 funcionários, sendo que os sistemas de controle de compras, pagamento de credores, contas a receber e gerenciamento do fluxo de caixa se destacaram como sendo os mais utilizados. Ainda, as empresas com menor tempo de mercado e com gestores que possuem educação continuada tendem a utilizar a contabilidade para fins gerenciais, enquanto que empresas com maior tempo de mercado e com pouca educação continuada, tendem a utilizar a contabilidade somente para fins fiscais. Esse estudo contribui para reforçar a importância da contabilidade gerencial para as microempresas/empresas de pequeno porte, pois dentre outras coisas, a sua utilização permite a elaboração de índices econômico-financeiros que auxiliam a tomada de decisão e por consequência propiciam a sobrevivência e crescimento da empresa.
Palavras-Chave: Informação. Contabilidade. Gestão. Micros e Pequenas Empresas.