bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of eculizumab in pregnancy-associated atypical hemolytic uremic syndrome
Authors: Misal Meenal , Gupta Megha , Platt Lawrence D. , Silverman Neil S. , Han Christina S. 
Published: February 2018

Abstract
Pregnancy-associated atypical hemolytic uremic syndrome (p-aHUS) is a rare disorder, with an estimated incidence of 1 in 25,000 pregnancies [Fakhouri F, Roumenina L, Provot F, Sallee M, Caillard S, Couzi L, et al. Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J Am Soc Nephrol. 2010;21:859–67.]. Unlike classic hemolytic uremic syndrome (HUS), aHUS is not related to Escherichia coli 0157:H7 infections. Rather, it arises from uncontrolled alternative complement pathway activation leading to diffuse endothelial damage. The formation of the resulting fibrin and platelet microthrombi in the vasculature leads to hemolysis, thrombocytopenia and ischemic end-organ damage in the form of acute kidney injury [Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med. 2009;361:1676–87; Legendre CM, Licht C, Muus P, Greenbaum LA, Babu S, Bedrosian C, et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med. 2013;368:2169–81; Loirat C, Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011;6:60; Shen YM. Clinical evaluation of thrombotic microangiopathy: identification of patients with suspected atypical hemolytic uremic syndrome. Thromb J. 2016;14(Suppl 1):19.]. Triggers for hyperactivation of the complement pathway include infection, inflammation, malignancy, endothelium-affecting drugs, maternal-fetal hemorrhage and pre-eclampsia [Shen YM. Clinical evaluation of thrombotic microangiopathy: identification of patients with suspected atypical hemolytic uremic syndrome. Thromb J. 2016;14(Suppl 1):19.]. Thirty percent of individuals with aHUS are found to have mutations in the genes encoding complement regulatory proteins, such as protein factor H, complement factor I and complement 3 [Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med. 2009;361:1676–87; Loirat C, Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011;6:60.]. Outcomes of an untreated aHUS are poor: up to 50% of patients with aHUS progress to end-stage renal disease within a year and 25% die during the acute phase [Loirat C, Fremeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011;6:60; Laurence J, Haller H, Mannucci PM, Nangaku M, Praga M, Rodriguez de Cordoba S. Atypical hemolytic uremic syndrome (aHUS): essential aspects of an accurate diagnosis. Clin Adv Hematol Oncol. 2016;14(Suppl 11):2–15.]. We present an unusual case of a 37-year-old primigravida who developed p-aHUS in the setting of hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. She was successfully treated with a relatively novel medication; eculizumab, a terminal complement inhibitor. In contrast to previous reports of long-term treatment, she received a total of six doses of eculizumab and remained in remission at 12 months postpartum.
Uterine rupture of a non-communicating rudimentary horn pregnancy with resultant successful outcome of an extremely premature baby born at 24 weeks of gestation
Authors: Pegu Satyaranjan , Deb Bakul , Peters Tara , Rattray Darrien 
Published: February 2018

Abstract
Mullerian anomalies occur in about 0.5% of reproductive-aged women; many remain asymptomatic only being discovered during surgery or on imaging done for unrelated reasons. These result from the abnormal formation, fusion or resorption of the mullerian duct during development. A unicornuate uterus with a rudimentary horn is one of the rarer subtypes, with such anomalies making up about 5% of all mullerian anomalies. Pregnancy in a non-communicating uterine horn (NCUH) is extremely rare, with an incidence between 1:100,000 and 1:140,000. There is a high risk of uterine rupture if pregnancy occurs in a non-communicating uterine horn. We present here a case of a non-communicating rudimentary horn pregnancy, with a successful outcome.
Littoral cell angioma with splenic rupture in pregnancy
Authors: McHugh Ann , O’Gorman Catherine , Cooley Sharon , McEntee Gerry , Burke Naomi 
Published: February 2018

Abstract
Splenic rupture in pregnancy is a rare event. It is generally due to trauma or an underlying splenic pathology. Timely diagnosis and intervention of splenic rupture is essential given the high rates of associated maternal and fetal morbidity and mortality. This case illustrates a 38 year old lady in the third trimester of pregnancy who presented with maternal collapse and a non-reassuring foetal heart rate tracing following a fall at home one week previously. A massive hemoperitoneum was identified at caesarean section and a splenectomy was performed. Histological examination revealed a littoral cell angioma of the spleen. This vascular tumour arising in the splenic red pulp sinuses is a rare entity and specific immunophenotypic features help distinguish it from other vascular tumours of the spleen. Both trauma and an underlying splenic pathology led to splenic rupture in this unique case.
Reproduction abilities of Ips typographus (L.) (Coleoptera: Curculionidae, Scolytinae) in the stands damaged by the wind in 2013 in the Kościeliska Valley (Tatra National Park)
Authors: Grodzki Wojciech , Fronek Wojciech Gąsienica 
Published: February 2018

Abstract
At the end of 2013, strong wind destroyed spruce stands on large areas of Kościeliska Valley in Tatra Mts. in Poland. In 2015–2017, 304 bark samples were collected from 106 spruces; 25 cm × 25 cm large samples were taken from 2 or 4 sections of infested trees in July/August each year. The infestation density, sex ratio, length of maternal galleries, number of progeny and impact of natural enemies were recorded. The infestation density in individual years was 0.79–0.86 mating chambers per dm2, the average length of maternal gallery (55.2–56.6 mm) did not differ between years, The average number of progeny per female from 3-year pooled data was 18.22, the highest in 2015 (27.4) then collapsed to 15.5–16.8. The gallery systems with 2 females, in which the reproduction success was the highest, dominated (62.6%). The frequency of parasitoids or entomopathogens was very low (2–20% mortality rate in 19 bark samples). Possible reasons of relatively low reproduction success regardless generally favourable breeding conditions and its collapse after first year, such as high infestation density and low survival rate of larvae because of climatic conditions (drought), are discussed. Taking into account the described population features, very intense tree mortality and mechanisms known from the other wind events, further development of the outbreak can be expected in this area.
Relationship between particular dendrobiometrical indicators of natural European beech (Fagus sylvatica L.) dendrocenoses in Central Balkan Range
Authors: Ferezliev Angel 
Published: February 2018

Abstract
In parallel studies, different regression models were tested to identify relationships between particular dendrobiometrical indicators on two sample plots representing forests dominated by the European beech in the Central Balkan Range (Bulgaria). The presence of incomplete multicollinearity was studied through correlation matrix for factor variables. To avoid multicollinear negative impact, step multiple regression was applied and adequate regression equations of the relationships under consideration were formulated. The results of statistical analysis confirmed that the link between the investigated indicators is strong and that the ’cloud‘ data show some ’sphericity‘ and distribution close to normal. In one of the sample plots, one major volume-forming factor – height does not participate in the obtained regression equation, so it is not possible to estimate its influence. By testing linear and several nonlinear regression dependencies and by mediating widely used statistical criterions for model selection, the optimal linear model of the considered link was chosen.
Characteristics of physical properties in soil profiles under selected introduced trees in the Nature Reserve Arboretum Mlyňany, Slovakia
Authors: Polláková Nora , Šimanský Vladimír , Jonczak Jerzy 
Published: February 2018

Abstract
The relationship between introduced trees roots and soils in which they grow is the most important factor influencing the adaptation, growth and health of these trees. Therefore, the objective of this study was to identify which physical soil properties enhance or limit the vitality of the studied introduced trees in the Arboretum Mlyňany. Soil properties were studied in seven soil profiles under dense monocultures of Chamaecyparis lawsoniana, Liriodendron tulipifera, Juniperus Chinensis, Thuja orientalis, Thuja plicata, Picea orientalis and Pinus nigra. The results showed that all stagnic horizons had exceeded the limit values of total porosity and bulk density, hence these horizons were compacted. Based on the soil and climatic requirements of the examined trees we conclude that the soil properties of their sites in arboretum are suitable for: Chamaecyparis lawsoniana, Liriodendron tulipifera, Thuja orientalis and Pinus nigra. Nevertheless, physical properties in profiles under Picea orientalis and Juniperus Chinensis do not permit rapid drainage of water, what is unfavourable for healthy development of these two species; while Thuja plicata demanding high moisture supply is grown on soil with high coarse porosity, a prerequisite of fast rainwater drainage. However, since none of the studied introduced trees had suffered from physiological disorders or diseases, they may be declared acclimatized well in the soil-climate conditions described in this study.
Adverbial Markers of Modality in Norwegian L1 and L2 Conversations
Authors: Horbowicz Paulina 
Published: February 2018

AbstractThe aim of this paper is to investigate how second language speakers of Norwegian (henceforth Norwegian L2 speakers) differ in their use of modality expressions from native speakers (L1 speakers). As modality is a very broad subject, the main focus of the study is limited to one-word modal adverbs, such askanskje‘maybe’, and modal particles such asjo. The study compares the frequency of using different types of modal adverbials by L1 and L2 speakers, and their syntactic position. The implications of the study are two-fold. First of all, it is to contribute to the studies of the field of modality in Norwegian. The second implication is didactic, as describing the use of modal adverbials in Norwegian conversation can help devise right teaching materials to allow second language users achieve a more native-like competence in this respect.
Flow-mode biodiesel production from palm oil using a pressurized microwave reactor
Authors: Safieddin Ardebili Seyed Mohammad , Ge Xinyu , Cravotto Giancarlo 
Published: February 2018

Abstract
The factors that influence microwave-assisted biodiesel production reactions have been analyzed in this investigation. The studied parameters included microwave (MW) power, irradiation time, and reactor pressure. The response surface method was used to optimize the reaction conditions. The conversion for the 6:1 methanol/oil molar ratio and 1% catalyst ranged from 68.4% to 96.71%. The optimized conditions were found to be 138 s of MW irradiation at 780 W and 7 bar pressure. The conversion at this point was 97.82%. Biodiesel yield increased at higher radiation times (90–130 s) and pressures (5–7 bar). Results show that MW power and irradiation time have significant effects at the 1% level, whereas pressure had significant effects at the 5% level on biodiesel production in this range. The major properties of the palm oil biodiesel produced herein have met the requirements of the EN 14214 methyl ester standard.
A straightforward proof of Carleman estimate for second-order elliptic operator and a three-sphere inequality
Authors: Baldassari Lorenzo , Vessella Sergio 
Published: February 2018

Abstract
In this paper we provide a simple proof of a Carleman estimate for a second-order elliptic operator P with Lipschitz leading coefficients. We apply such a Carleman estimate to derive a three-sphere inequality for solutions to equation

P
⁢
u

=
0

{Pu=0}

.
The Roman Road System in the Golan: Highways, Paths and Tracks in Quotidian Life
Authors: Pažout Adam 
Published: February 2018

Abstract
Roman Imperial Roads (highways) built, maintained and organized by the Roman army and provincial authorities were studied in the Golan Heights since Schumacher’s surveys in the 1880s. However, most of these were obliterated by building and agricultural activity since the beginning of the 20th century. Local ancient road system, linking individual communities and their agricultural land was never studied, since it barely leaves a trace in archaeological record. This paper presents reconstruction of inter-provincial highways passing through the southern Golan Heights, and local road system in GIS using cumulative focal mobility network (CFMN) analysis. The CFMN provides outline of natural corridors of movement in the region. From CFMN it is possible to extract path with higher mobility potential which will be tested against present evidence for Roman Imperial Highways, since it is assumed that corridors with high mobility potential would be suitable place for construction of (inter-)provincial road. Path with lower mobility potential might indicate local road system, so it would be possible to connect agricultural communities with the land they exploited; which in turn may have implications for site prediction and site-catchment analysis exploring quotidian movement of people and goods in the landscape. Two case studies in this respect are presented: the city of Hippos and settlement of es-Safuriyye.
Economic Conditions in the Area Around the Sea of Galilee in Pre-Hellenistic Times
Authors: Zwickel Wolfgang 
Published: February 2018

Abstract
In a landscape archaeology project all the fertile fields around the Sea of Galilee (an area of 50 × 30 km) were mapped. The whole territory was subdivided in 5 regions: Jordan valley, Lower Galilee, Upper Galilee, Golan and Transjordanian Hill Country. Additionally all ancient sites from the Neolithic to the Persian period, which are mentioned in archaeological literature, were collected – all together more than 300 sites. These data allow a reconstruction of the economic conditions in antiquity in the area around the Sea of Galilee. Landscape archaeology clearly demonstrates that the economic basis may have been completely diverse in the five sub-regions, and also during different times. Agriculture played a major role in the economy of ancient people. During some periods and in some regions people lived in the midst of the fields, while in other periods they settled at the edges in order not to waste valuable farmland. On the other hand the position of some sites in some periods clearly demonstrates that trade played a major role for the income of the settlers, or basalt mining and working. Streets can be reconstructed, and our methodological approach allows new insights in the economy of this area
Publishing Landscape Archaeology in the Digital World
Authors: Howry Jeffrey C. 
Published: February 2018

Abstract
The challenge of presenting micro- and macro-scale scale data in landscape archaeology studies is facilitated by a diversity of GIS technologies. Specific to scholarly research is the need to selectively share certain types of data with collaborators and academic researchers while also publishing general information in the public domain. This article presents a general model for scholarly online collaboration and teaching while providing examples of the kinds of landscape archaeology that can be published online. Specifically illustrated is WorldMap, an interactive mapping platform based upon open-source software which uses browsers built to open source standards. The various features of this platform allow tight user viewing control, views with URL referencing, commenting and certification of layers, as well as user annotation. Illustration of WorldMap features and its value for scholarly research and teaching is provided in the context of landscape archaeology studies.
Evidentiary means in feudal Transylvania. Ordeal By fire (holding a red-hot iron)
Authors: Florin Moldovan Iosif 
Published: February 2018

Abstract
One of the evidentiary means used in medieval legal procedure was the so-called judgment of God, judicium dei, also known as ordeal, from the Latin term ordalium. Ordeals were characteristic of all peoples in their various stages of development. They were based on the belief that divinity could intervene and perform miracles, disregarding the laws of nature, in order to prove one’s innocence. In the Middle Ages ordeals were widespread on the territory of Transylvania, too, the ordeal of fire being one of the most commonly used means of proof. In this paper I will try to show the characteristics of this evidence in relation to others that were used at that time, looking at them through the lenses of the documents of the time and of personal research.
Operational validation of HYDRUS (2D/3D) for capillary barriers using data of a 10-m tipping trough
Authors: Berger Klaus 
Published: February 2018

Abstract
Capillary barriers are an interesting alternative component for cover systems of landfills and contaminated sites. Provided they are sufficiently validated, soil hydrological models could be fast and powerful tools for the dimensioning of capillary barriers. Outflow rates measured in a 10 m long tipping trough for one material combination and two slopes from stationary periods were compared to simulation results of HYDRUS (2D/3D), Version 2.05. The measured outflow rates show a typical pattern with slope-dependent threshold values indicating the efficiency of the capillary barrier. This flow pattern could not be reproduced with HYDRUS (2D/3D) that for different input setups produced smooth patterns without thresholds. The input setup was varied for different soil hydraulic models (van Genuchten-Mualem vs. Brooks-Corey), homogeneous and heterogeneous transport domains (no scaling vs. stochastically distributed scaling factors considering the Miller-Miller similitude), different HYDRUS versions (standard vs. alternative; i.e., with material properties assigned either to finite element nodes or finite elements, respectively), and different lower boundary conditions (seepage face vs. free drainage). Differences between measured and simulated outflow patterns could be caused by the measurements, the application of the model, or by the model itself. The van Genuchten-Mualem model may not be suitable to describe the soil hydrological relationships of these particular materials. The reason for the mismatch, however, could not be identified yet.
Zero-divisor graphs of lower dismantlable lattices II
Authors: Patil Avinash , Waphare B. N. , Joshi Vinayak 
Published: February 2018

Abstract
In this paper, we continue our study of the zero-divisor graphs of lower dismantlable lattices that was started in [PATIL, A.—WAPHARE, B. N.—JOSHI, V.—POURALI, H. Y.: Zero-divisor graphs of lower dismantlable lattices I, Math. Slovaca 67 (2017), 285–296]. The present paper mainly deals with an Isomorphism Problem for the zero-divisor graphs of lattices. In fact, we prove that the zero-divisor graphs of lower dismantlable lattices with the greatest element 1 as join-reducible are isomorphic if and only if the lattices are isomorphic.
Crystal structural of 2-amino-4-(3-bromophenyl)-3-cyano-7,7-dimethyl-5-oxo-4H-5,6,7,8-tetrahydrobenzo[b]pyran, C18H17BrN2O2
Authors: Song Jing 
Published: February 2018

Abstract
C18H17BrN2O2, monoclinic, C2/c (no. 15), a = 23.554(2) Å, b = 9.3060(8) Å, c = 15.7691(15) Å, β = 93.372(9)°, V = 3450.5(5) Å3, Z = 8, R
gt(F) = 0.0521, wR
ref(F
2) = 0.1686, T = 293 K.
Crystal structure of [(1,2-bis(dicyclohexylphosphino)-1,2-dicarba-closo-dodecaborane-κ2
P,P′]dibromidonickel(II)), C26H54B10NiBr2P2
Authors: Liguo Yang , Qingyun Liu , Xin Wang , Nana Liu , Yuqiang Dai 
Published: February 2018

Abstract
C26H54B10NiBr2P2, monoclinic, C2/c (no. 15), a = 13.064(7) Å, b = 15.655(8) Å, c = 16.652(9) Å, β = 95.830(7)°, V = 3388(3) Å3, Z = 4, R
gt(F) = 0.0603, wR
ref(F
2) = 0.1364, T = 298(2) K.
Proactive coping as a kind of creative adaptation to a new workplace
Authors: Ślebarska Katarzyna 
Published: February 2018

Abstract
The proactive dimension of human behavior is rooted in one’s need to create and control the environment. Individuals prefer to do things actively and creatively rather than being counteractive. The dynamics of the job market demand that individuals are increasingly independent and proactive, can easily adapt to change, and create their own future. This way of understanding a newcomer’s activity corresponds to proactive coping. The main goal of this study was to investigate the role of proactive coping of workers in a new workplace and in job adaptation outcomes, namely well-being. Data was collected from newly employed workers (N = 172) who agreed to participate in the study within a longitudinal evaluation design (one pre-test and a double post-test) during their first six months in a new workplace. Overall, the study demonstrates that proactive coping improves the adaptation of new employees, costing them less emotionally as they adjust to their new workplace. Additionally, the employees’ pre-entry experience (previously unemployed vs previously employed) moderated the relation between the analyzed variables.
Brundibár – A Children’s Opera: History and Present
Authors: Pirníková Tatiana 
Published: February 2018

Abstract
The paper focuses on the opera Brundibár. The authorial couple – composer Hans Krasa and librettist Adolf Hoffmeister – wrote it in the period of growing interest of artists in pedagogical aspects of the works of art. The changed social climate, however, meant for the work an unplanned journey – during the Second World War it was performed inside the Terezin ghetto by its inhabitants. The human message of the fairy tale story has thus been elevated into a higher symbolic frame – a resistance against the arrogance of power and violence. Especially the post-war era followed this symbolism. The author of the paper contemplates the innovative interpretative levels whose ambition is to cross the traditional performance frame of the work and to find connections with problems of contemporary society.
Interplay of Brain-Derived Neurotrophic Factor and Cytokines in Schizophrenia
Authors: Janicijevic Slavica Minic , Dejanovic Slavica Djukic , Borovcanin Milica 
Published: February 2018

AbstractBrain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family and plays an important role in neuroplasticity, differentiation and survival of neurons, as well as their function. Neuroinflammation has been explored in the pathophysiology of many mental disorders, such as schizophrenia. Cytokines representing different types of immune responses have an impact on neurogenesis and BDNF expression. Cross-regulation of BDNF and cytokines is accomplished through several signalling pathways. Also, typical and atypical antipsychotic drugs variously modulate the expression of BDNF and serum levels of cytokines, which can possibly be used in evaluation of therapy effectiveness. Comorbidity of metabolic syndrome and atopic diseases has been considered in the context of BDNF and cytokines interplay in schizophrenia.