bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a suite of metrics and indicators for children’s nursing using consensus methodology
Authors: Brenner Maria , Browne Catherine , Gallen Anne , Byrne Susanna , White Ciara , Nolan Mary 
Published: March 2019

AbstractAim and objectivesTo develop a suite of metrics and indicators to measure the quality of children's nursing care processes. The objectives were to identify available metrics and indicators and to develop consensus on the metrics and indicators to be measured.BackgroundThe Office of Nursing and Midwifery Services Director, Health Service Executive, in Ireland established seven workstreams aligned to the following care areas: acute, older persons, children's, mental health, intellectual disability, public health nursing and midwifery.DesignA comprehensive design included stakeholder consultation and a survey with embedded open‐ended questions.MethodsA two‐round online Delphi survey was conducted to identify metrics to be measured in practice, followed by a two‐round online Delphi survey to identify the associated indicators for these metrics. A face‐to‐face consensus meeting was held with key stakeholders to review the findings and build consensus on the final metrics and indicators for use. A STROBE checklist was completed.ResultsA suite of eight nursing quality care process metrics and 67 associated process indicators was developed for children's nursing.ConclusionsBy creating a national suite of metrics and indicators, more robust measurement and monitoring of nursing care processes can be achieved. This will enable the provision of evidence for any local and/or national level changes to policy and practice to enhance care delivery.Relevance to clinical practiceThe roll‐out of the metrics and indicators in clinical practice has commenced. This national suite of metrics and indicators will ensure that a robust system of measurement for improvement is in place to provide assurance to Directors of Nursing of the quality of nursing care being provided to children and their families. It supports the value of nursing sensitive data to inform change and improvement in healthcare delivery and to demonstrate the contribution of the nursing workforce to safe patient care.
The development and psychometric validation of a Chinese empathy motivation scale
Authors: Zhu Yu , Zhan Yu‐can , Zhu Ji‐Min , Huang Li , Zhang Ling , Zhang Miao , Li Bai‐Kun 
Published: March 2019

AbstractAims and objectivesTo develop and validate an instrument to measure nurses’ empathy motivation in China (See Supporting Information Appendix S1).BackgroundNurses are increasingly expected to empathise with patients in clinical settings. However, research investigating nurses’ empathy motivation in China is lacking, and no specific instrument exists worldwide.DesignTwo‐stage cross‐sectional study, which follows the STROBE guidelines. Instrument development and psychometric evaluation were used (See Supporting Information Appendix S1).MethodsA literature review and qualitative interviews with nurses were conducted to generate the initial items. Convenience samples of 340 (for item analysis) and 640 (for psychometric evaluation) clinical nurses working at four tertiary hospitals in Anhui Province were recruited. The scale was validated by content validity, surface validity and item analysis. A total of 640 participants were randomly divided into two equal groups. Exploratory factor analysis (EFA) was used with varimax rotation, confirmatory factor analysis (CFA) and internal consistency reliability to analyse the psychometric properties of the scale (See Supporting Information Appendix S1).ResultsFrom the initial 90‐item pool, 27 items were retained by the item analysis. The EFA (N = 290) showed the following six factors on the scale explained 71.266% of the overall variance: amotivation, external regulation, introjected regulation, identified regulation, integrative regulation and intrinsic motivation. Furthermore, when limited to three factors, that is autonomy motivation, controlled motivation and amotivation, 56.578% of the variance was explained. The findings showed high internal consistency. The six‐factor solution and three‐factor solution of the scale, including 27 items, were both confirmed by the CFA, for example χ2/df = 1.744, 2.261; RMSEA = 0.051, 0.066; GFI = 0.882, 0.847; TLI = 0.942, 0.902; and RMR = 0.039, 0.049, respectively.ConclusionsThe nurses’ empathy motivation scale presents good psychometric properties and can be used to explore nurses’ empathy motivation in China (See Supporting Information Appendix S1).Relevance to clinical practiceThis study offers insight into nurses’ complicated reasons for exhibiting empathy.
The prevalence of awake bruxism and sleep bruxism in the Dutch adult population
Authors: Wetselaar Peter , Vermaire Erik (J. H.) , Lobbezoo Frank , Schuller Annemarie A. 
Published: March 2019

SummaryBackgroundAwake bruxism and sleep bruxism are common conditions amongst adult populations, although prevalence data are scarce.ObjectiveThis study aimed to assess the prevalence of awake bruxism and sleep bruxism in the Dutch adult population.MethodsAs part of a large epidemiologic survey on oral health of the general Dutch adult population, a total of 1209 subjects were asked about their bruxism behaviour during the day and during their sleep. The collected data were subjected to stratified analysis by five age groups (25‐34, 35‐44, 45‐54, 55‐64 and 65‐74 years), socioeconomic status, and gender.ResultsA prevalence of 5.0% of the total population was found for awake bruxism and of 16.5% for sleep bruxism. Regarding the five age groups, prevalence of 6.5%, 7.8%, 4.0%, 3.2% and 3.0%, respectively, were found for awake bruxism, and of 20.0%, 21.0%, 16.5%, 14.5% and 8.3%, respectively, for sleep bruxism. Women reported both awake bruxism and sleep bruxism more often than men. These differences were statistically significant. Concerning socioeconomic status (SES), both awake bruxism and sleep bruxism were more often found in high SES groups, being statistically significant for awake bruxism only.ConclusionSleep bruxism is a common condition in the Dutch adult population, while awake bruxism is rarer.
Influence of information received by the consumer on the sensory perception of processed orange juice
Authors: Pereira Geovanna S. , Honorio Alice R. , Gasparetto Bruna R. , Lopes Carla M. A. , Lima Diana C. N. d. , Tribst Alline A. L. 
Published: March 2019

AbstractThis study evaluated how the sensory perception of fresh and different types of processed juice changes according to the information received by 753 consumers. Fresh, pasteurized, commercially sterilized, frozen concentrated, fruit liquid concentrated, and powered drink mix orange juices were selected as the types of juice. Acceptance and check‐all‐that‐apply tests were carried out in three different conditions: (a) blind, (b) informed (juice processing characteristics, price, ingredients, and shelf‐life), and (c) given the information relative to each type of juice, although the samples tasted were identical and comprised a mix of fresh, sterilized, and powdered drink juices. Results showed that fresh juice was preferred in all tests (even in c, when the same juice mix was served for all samples) and that the acceptance of processed juices (mainly pasteurized, sterilized, and frozen concentrated) was higher in the informed tests. Moreover, the third test (serving the same juice mix) clearly showed how positive–negative information can change the consumer perception about the product. These results highlight the need to improve consumers' access to information about juice processes, helping them to be more aware of processed food products.Practical ApplicationConsumers' rejection regarding processed juices is growing due to associating them with processed food and adverse health effects. Results of this study show that consumers easily recognize and prefer fresh juice and consistently reject processed samples when no information about the products is given. On the other hand, information on processing characteristics, ingredients, durability, and price positively influenced consumer acceptance of processed juices, especially those produced only with oranges (without sugar, water, or additives), regardless of the form of processing. Therefore, the juice industry can use consumer access to information about product characteristics as a marketing strategy.
Reflectance spectroscopy of insoluble organic matter (IOM) and carbonaceous meteorites
Authors: Kaplan Hannah H. , Milliken Ralph E. , Alexander Conel M. O'D. , Herd Christopher D. K. 
Published: March 2019

AbstractInsoluble organic matter (IOM) is the major organic component of chondritic meteorites and may be akin to organic materials from comets and interplanetary dust particles (IDPs). Reflectance spectra of IOM in the range 0.35–25 μm are presented as a tool for interpreting organic chemistry from remote measurements of asteroids, comets, IDPs, and other planetary bodies. Absorptions in the IOM spectra were strongly related to elemental H/C (atom) ratio. The aliphatic 3.4 μm absorption in IOM spectra increased linearly in strength with increasing H/C for H/C > 0.4, but was absent at lower H/C values. When meteorite spectra from the Reflectance Experiment Laboratory (RELAB) spectral catalog (n = 85) were reanalyzed at 3.4 μm, this detection limit (H/C > 0.4) persisted. Aromatic absorption features seen in IOM spectra were not observed in the meteorite spectra due to overlapping absorptions. However, the 3.4 μm aliphatic absorption strength for the bulk meteorites was correlated with both H/C of the meteorite's IOM and bulk C (wt%). Gaussian modeling of the 3 μm region provided an additional estimate of bulk C for the meteorites, along with bulk H (wt%), which is related to phyllosilicate abundance. These relationships lay the foundation for determining organic and phyllosilicate abundances from reflectance spectra. Both the full IOM spectra and the spectral parameters discussed here will aid in the interpretation of data from asteroid missions (e.g., OSIRIS‐REx, Hayabusa2), and may be able to place unknown spectral samples within the context of the meteorite collection.
Joseph Ratzinger's Debates with Gisbert Greshake: An Argument for the Resurrection of Matter
Authors: Ehrman Terrence P. 
Published: March 2019

AbstractDebates in eschatology have been unresolved regarding the place of earthly matter in the resurrection. I analyze the positions of Joseph Ratzinger and Gisbert Greshake and argue in favor of Ratzinger's position. He defends a transphysical bodily resurrection that involves the matter of this world over against Greshake's resurrection in death eschatology and anthropology that entails the resurrection of a phenomenological but not a physical body. What is at stake in this debate is nothing less than the meaning of creation in God's salvific economy.
Genetic dissection of haploid male fertility in maize (Zea mays L.)
Authors: Yang Jiwei , Qu Yanzhi , Chen Qiong , Tang Jihua , Lübberstedt Thomas , Li Haochuan , Liu Zonghua 
Published: March 2019

AbstractHaploid genome doubling is a key limiting step of haploid breeding in maize. Spontaneous restoration of haploid male fertility (HMF) provides a more promising method than the artificial doubling process. To reveal the genetic basis of HMF, haploids were obtained from the offspring of 285 F2:3 families, derived from the cross Zheng58 × K22. The F2:3 families were used as the female donor and Yu high inducer No. 1 (YHI‐1) as the male inducer line. The rates of HMF from each family line were evaluated at two field sites over two planting seasons. HMF displayed incomplete dominance. Transgressive segregation of haploids from F2:3 families was observed relative to haploids derived from the two parents of the mapping population. A total of nine quantitative trait loci (QTL) were detected, which were distributed on chromosomes 1, 3, 4, 7 and 8. Three major QTL, qHMF3b, qHMF7a and qHMF7b were detected in both locations, respectively. These QTL could be useful to predict the ability of spontaneous haploid genome doubling, and to accelerate the haploid breeding process by introgression or aggregation of those QTL.
Severe, persistent neurotoxicity after transplant‐associated thrombotic microangiopathy in a pediatric patient despite treatment with eculizumab
Authors: Schoettler Michelle , Duncan Christine , Lehmann Leslie 
Published: March 2019

AbstractBackgroundTA‐TMA is a described complication of aHCT in children with neuroblastoma. Outcomes are poor with mortality rates approaching 60%. Described late effects in survivors include chronic kidney disease and persistent pulmonary hypertension.CaseWe report a case of a 2‐year‐old with neuroblastoma who developed severe TA‐TMA 35 days after high dose chemotherapy and autologous stem cell rescue. He presented with respiratory failure, pericardial and pleural effusions, hemolysis, hypertension, and mild altered mental status. He was mechanically ventilated for 3 weeks and after sedation was lifted, he was minimally responsive. He was treated with eculizumab with resolution of hemolysis, kidney injury and polyserositis. Initially he was more responsive; however, after almost a year of intensive therapy he remained nonverbal and had persistent irritability and behavioral changes. He had an extensive negative evaluation. On day +345, he presented with severe, refractory epilepsy. Three years after TA‐TMA, he continues to have severe neurologic disabilities.ConclusionsTo our knowledge, persistent neurologic toxicity has not been reported in TA‐TMA. However, deficits and seizures are reported in other TMAs, particularly in children with atypical HUS who present with significant neurologic changes at diagnosis. Our patient's persistent neurologic disability despite eculizumab response in all other involved organs may reflect irreversible damage. This case describes a new long‐term sequela of TA‐TMA and highlights the need for further studies to understand both acute and long‐term neurologic complications of this disease.
Induced antimicrobial activity in heat‐treated woodchips inhibits the activity of the invasive plant pathogen Phytophthora ramorum
Authors: Kalantarzadeh M. , Mulholland D. A. , De Leij F. A. A. M. , Webber J. F. 
Published: March 2019

The antimicrobial activity of heat‐treated woodchips of three woody host species against the invasive oomycete plant pathogen Phytophthora ramorum was investigated to assess the potential of heated woodchips to suppress disease. Results demonstrated that heat‐treated woodchips of pine (Pinus sylvestris), Japanese larch (Larix kaempferi) and rhododendron (Rhododendron ponticum) inhibited recovery of P. ramorum spores and mycelium compared with similar material that had only been air‐dried. Effects were most evident with pine and larch; inhibition was maintained even when larch woodchips were diluted with soil. In vitro assays using methanol crude extracts from woodchips of the three species showed they all had an inhibitory effect on P. ramorum zoospores and reduced chlamydospore germination compared with air‐dried wood extracts. Chemical analysis of the extracts revealed several induced compounds were present but in different concentrations for each species. Coniferaldehyde was the most active inhibitor against spores and mycelium, while the dominant resin acids, dehydroabietic and abietic acid, decreased the minimum inhibitory concentration of phenolic compounds tested against P. ramorum but were ineffective when used alone. An array of compounds, including dehydroabietic acid, methyl abietate, α‐pinene and 3‐carene, occurred at elevated levels in the living tissue of Japanese larch bark attacked by P. ramorum. These compounds may be part of the induced resistance response of larch to P. ramorum. Results of a field trial using heat‐treated and air‐dried woodchips were consistent with the crude extract bioassay results, suggesting that heat‐treated woody materials have potential to reduce the survival of P. ramorum under natural conditions.
Environmental controls on the development of Mississippian microbial carbonate mounds and platform limestones in southern Montagne Noire (France)
Authors: Cózar Pedro , Izart Alain , Somerville Ian D. , Aretz Markus , Coronado Ismael , Vachard Daniel 
Published: March 2019

AbstractLate Mississippian carbonates in southern Montagne Noire are dominantly domical to laterally‐accreted microbial mounds in some formations, as well as stratiform microbial limestones occurring in hundreds of olistoliths within a flysch basin, constituting pieces of a giant puzzle that are used to help reconstruct a platform in a region that is no longer preserved. Petrographic data of limestone samples from 14 continuous long sections of olistoliths have been analyzed statistically, using multivariate clustering (Q‐mode) of the components/matrix/cement and canonical correspondence analysis that allow the reconstruction of the environmental parameters of carbonate microbial communities in space and time. Clustering analysis separated microbial and non‐microbial facies. The calculation of indices along the various axes from canonical correspondence analysis allows recognition of the controlling factors of the mounds and microbial growth as being turbidity, light penetration, bathymetry and storms. Turbidity and light penetration are the primary factors controlling the morphology of the microbial limestones. Representation of the light penetration and bathymetry indices on the stratigraphical sections defines two vertical environmental gradients. Light penetration can be subdivided into euphotic, euphotic–dysphotic and dysphotic‐aphotic conditions. The representation of the bathymetry allows the subdivision of samples into a deeper outer ramp, external mid‐ramp and internal mid‐ramp. The curve distance from the section base = f (index) suggests a cyclicity for the platform that cannot be compared with the onlap curve defined from other cratonic areas (Moscow Basin), and thus the cyclic succession of the Montagne Noire is interpreted to have been mostly tectonically‐controlled. Integration of the data allowed the reconstruction of the original Mississippian carbonate platform, where, up to the Mikhailovian, it appears to correspond to a platform morphology, with narrow shallow water facies and wide turbiditic systems, whereas the width of shallow‐water settings expanded during the Venevian to the Protvian, forming a ramp or distally‐steepened ramp with widespread microbial limestones.
The HDA19 histone deacetylase complex is involved in the regulation of flowering time in a photoperiod‐dependent manner
Authors: Ning Yong‐Qiang , Chen Qing , Lin Rong‐Nan , Li Yong‐Qiang , Li Lin , Chen She , He Xin‐Jian 
Published: March 2019

SummaryChromatin modifications are known to affect flowering time in plants, but little is known about how these modifications regulate flowering time in response to environmental signals like photoperiod. In Arabidopsis thaliana, HDC1, a conserved subunit of the RPD3‐like histone deacetylase (HDAC) complex, was previously reported to regulate flowering time via the same mechanism as does the HDAC HDA6. Here, we demonstrate that HDC1, SNLs and MSI1 are shared subunits of the HDA6 and HDA19 HDAC complexes. While the late‐flowering phenotype of the hda6 mutant is independent of photoperiod, the hda19, hdc1 and snl2/3/4 mutants flower later than or at a similar time to the wild‐type in long‐day conditions but flower earlier than the wild‐type in short‐day conditions. Our genome‐wide analyses indicate that the effect of hdc1 on histone acetylation and transcription is comparable with that of hda19 but is different from that of hda6. Especially, we demonstrate that the HDA19 complex directly regulates the expression of two flowering repressor genes related to the gibberellin signaling pathway. Thus, the study reveals a photoperiod‐dependent role of the HDA19 HDAC complex in the regulation of flowering time.
Estimating the risk of blood donation fainting for self versus others: the moderating effect of fear
Authors: France Christopher R. , France Janis L. 
Published: March 2019

BACKGROUNDPeople overestimate the likelihood that blood donors will experience faint and prefaint reactions, particularly if they are themselves fearful of having blood drawn. This study investigated the influence of making a risk assessment for oneself versus others, and examined whether providing information about the low base rates of reactions affected donation attitude, anxiety, and intention.STUDY DESIGN AND METHODSAn anonymous online survey was completed by 3702 individuals (53.9% female; mean age, 36.9 years; standard deviation, 12.1 years; range, 18–84) that included questions about fear of having blood drawn and estimation of the risk of donation‐related faint and prefaint symptoms for themselves and others. A random one‐half of the respondents received accurate information about the proportion of whole blood donors who experience such reactions before all participants completed questions concerning their donation attitude, anxiety, and intention.RESULTSEstimates of both faint and prefaint reactions revealed a pattern of lower perceived risk for self versus others among individuals with low fear, and higher perceived risk for self versus others among those with high fear. Provision of accurate information about risk of reactions was associated with more positive donation attitudes (F[1, 3692] = 8.182, p = 0.004) and intentions (F[1, 3692] = 10.137, p = 0.001) but did not significantly affect anxiety.CONCLUSIONDonation‐related fear is associated with inflated expectancies of adverse events, especially regarding oneself. Such fear may be particularly important to address, as it has both a direct and indirect negative effect on donor retention.
Characterization of the otic bacterial microbiota in dogs with otitis externa compared to healthy individuals
Authors: Korbelik Juraj , Singh Ameet , Rousseau Joyce , Weese J. Scott 
Published: March 2019

BackgroundOtitis externa is a common multifactorial disease in dogs. The diversity of the cutaneous microbiota in dogs appears to decrease in diseased states. However, little is known about the microbiota of the canine ear and how it is altered by disease.Hypothesis/ObjectivesTo describe the otic bacterial microbiota in dogs with otitis externa compared to healthy dogs.AnimalsSamples were collected from 18 dogs with clinical and cytological evidence of otitis externa, and eight clinically normal dogs without cytological evidence of otitis externa.Methods and materialsDNA from each sample was isolated and Illumina® sequencing of the V4 hypervariable region of the 16S rRNA gene amplicons was performed. Sequences were processed using the bioinformatics software MOTHUR.ResultsBacteria from 27 different phyla were identified. Affected ears had significantly decreased alpha diversity when compared to healthy ears. Community structure and membership also differed between the two groups. Linear discriminant analysis effect size analysis identified 153 operational taxonomic units (OTUs) that were differentially abundant. Eleven OTUs were over‐represented in the affected ears, including Staphylococcus, Pseudomonas and Parvimonas.ConclusionsThe otic bacterial microbiota is much more complex than has been identified with previous culture‐based studies; otitis externa is accompanied by broad and complex differences in the microbiota.