bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomized controlled clinical study of veneered zirconia abutments for single implant crowns: Clinical, histological, and microbiological outcomes
Authors: Thoma Daniel S. , Sailer Irena , Mühlemann Sven , Gil Alfonso , Jung Ronald E. , Hämmerle Christoph H. F. 
Published: October 2018

AbstractObjectivesTo analyze the effect of veneering of the submucosal part of zirconia abutments and the type of retention (cemented vs screw‐retained) on clinical, microbiological, and histological outcomes of single‐tooth implant crowns.Material and MethodsA total of 44 patients with a single missing tooth to be replaced by an implant in the anterior region participated in the study. Implants were randomly assigned to receive zirconia‐based CAD/CAM reconstructions using either one of four treatment modalities: cement‐retained with submucosal veneering (CR‐P), cement‐retained without submucosal veneering (CR‐W), screw‐retained with submucosal veneering (SR‐P), and screw‐retained without submucosal veneering (SR‐W). Clinical parameters were assessed at baseline (after crown insertion), at 6 and 12 months. Histological and microbiological analyses were performed at 6 months. Descriptive statistics and the Kruskal‐Wallis test were applied.ResultsThe clinical evaluation revealed, in general, stable peri‐implant soft tissues with minimal differences for all measured parameters between the four groups, except for bleeding on probing with the two cemented groups exhibiting higher values at 12 months (35.0% ± 26.5% for CR‐W and 25.0% ± 38.8% for CR‐P versus 13.1 ± 14.8 for SR‐W and 13.0 ± 18.2 for SR‐P). The descriptive and semi‐quantitative histology showed a trend for a higher inflammatory reaction in the two cemented (a medium to high number of inflammatory cells) compared to the screw‐retained groups (low number of inflammatory cells) at 6 months. The microbiological test demonstrated low bacterial counts and a similar distribution in between the groups except for two species (Tannerella forsythia and Peptostreptococcus micros) that were found in higher counts in the cemented groups at 6 months.ConclusionSubmucosal veneering of zirconia abutments did not negatively affect the health of the peri‐implant tissues. The cemented groups, though, did show a clinical and histological trend to higher levels of inflammation.
The diagnosis of peri‐implantitis: A systematic review on the predictive value of bleeding on probing
Authors: Hashim Dena , Cionca Norbert , Combescure Christophe , Mombelli Andrea 
Published: October 2018

AbstractObjectivesBleeding on gentle probing (BOP) is the key parameter to the diagnosis of mucositis, while changes in crestal bone levels, along with clinical signs of inflammation, are required for the diagnosis of peri‐implantitis. This systematic review and meta‐analysis focused on the evaluation of BOP as a predictive measure for peri‐implantitis.Materials and methodsAn electronic search was performed through Medline and EMBASE databases, followed by a hand search through previous reviews and reference lists. Screening, study selection, data extraction and evaluation of publication bias were conducted by two independent examiners. Clinical studies reporting on the prevalence of peri‐implantitis, BOP and/or suppuration (SUP) after more than 1 year of functional loading were selected. Meta‐analyses were conducted to combine the proportions of peri‐implantitis among BOP‐ and/or SUP‐positive subjects and implants across studies. Subgroups were created and compared to investigate potential sources of heterogeneity.ResultsThirty‐one studies were selected for analysis. Inconsistent definitions of peri‐implantitis were reported across the studies. Twenty‐nine studies reported data on implant‐level and twenty publications reported on subject‐level. The combined proportion of peri‐implantitis was 24.1% (95% CI 19.3–29.7) in BOP‐positive implants and 33.8% (95% CI 26.7–41.6) for BOP‐positive cases. However, the degree of variability among studies was high; the prediction intervals were 10.3‐69.3 and 6.9‐57.8, respectively. Evidence of asymmetry or publication bias could not be statistically detected. Short observation periods were significantly associated with lower proportions of peri‐implantitis among BOP‐positive implants.ConclusionsFor BOP‐positive implants, there was a 24.1% chance to be diagnosed with peri‐implantitis; while for BOP‐positive patients, there was a 33.8% probability to be diagnosed with peri‐implantitis. This probability varied across study populations. Clinicians should be aware of the considerable false‐positive rate of BOP to diagnose peri‐implantitis.
Group 3 ITI Consensus Report: Patient‐reported outcome measures associated with implant dentistry
Authors: Feine Jocelyne , Abou‐Ayash Samir , Al Mardini Majd , de Santana Ronaldo Barcelllos , Bjelke‐Holtermann Trine , Bornstein Michael M. , Braegger Urs , Cao Olivia , Cordaro Luca , Eycken Didier , Fillion Mathieu , Gebran Georges , Huynh‐Ba Guy , Joda Tim , Levine Robert , Mattheos Nikos , Oates Thomas W. , Abd‐Ul‐Salam Hani , Santosa Robert , Shahdad Shakeel , Storelli Stefano , Sykaras Nikitas , Treviño Santos Alejandro , Stephanie Webersberger Ulrike , Williams Mary Ann H. , Wilson Thomas G. , Wismeijer Daniel , Wittneben Julia‐Gabriela , Yao Coral Jie , Zubiria Juan Pablo Villareal 
Published: October 2018

AbstractObjectivesThe aim of Working Group 3 was to focus on three topics that were assessed using patient‐reported outcome measures (PROMs). These topics included the following: (a) the aesthetics of tooth and implant‐supported fixed dental prostheses focusing on partially edentulous patients, (b) a comparison of fixed and removable implant‐retained prostheses for edentulous populations, and (c) immediate versus early/conventional loading of immediately placed implants in partially edentate patients. PROMs include ratings of satisfaction and oral health‐related quality of life (QHRQoL), as well as other indicators, that is, pain, general health‐related quality of life (e.g., SF‐36).Materials and methodsThe Consensus Conference Group 3 participants discussed the findings of the three systematic review manuscripts. Following comprehensive discussions, participants developed consensus statements and recommendations that were then discussed in larger plenary sessions. Following this, any necessary modifications were made and approved.ResultsPatients were very satisfied with the aesthetics of implant‐supported fixed dental prostheses and the surrounding mucosa. Implant neck design, restorative material, or use of a provisional restoration did not influence patients’ ratings. Edentulous patients highly rate both removable and fixed implant‐supported prostheses. However, they rate their ability to maintain their oral hygiene significantly higher with the removable prosthesis. Both immediate provisionalization and conventional loading receive positive patient‐reported outcomes.ConclusionsPatient‐reported outcome measures should be gathered in every clinical study in which the outcomes of oral rehabilitation with dental implants are investigated. PROMs, such as patients’ satisfaction and QHRQoL, should supplement other clinical parameters in our clinical definition of success.
Early histological, microbiological, radiological, and clinical response to cemented and screw‐retained all‐ceramic single crowns
Authors: Thoma Daniel S. , Wolleb Karin , Bienz Stefan P. , Wiedemeier Daniel , Hämmerle Christoph H. F. , Sailer Irena 
Published: October 2018

AbstractObjectivesTo assess the early histological, microbiological, radiological, and clinical response to cemented and screw‐retained all‐ceramic single‐tooth implant‐supported reconstructions.Materials and methodsPatients with single‐tooth implants were randomly allocated to receive a cemented lithium disilicate crown on a customized zirconia abutment (CEM) or a screw‐retained crown with a directly veneered zirconia abutment (SCREW). At the screening visit, at crown insertion and at the 6‐month follow‐up, clinical parameters were measured at the implant and the contralateral tooth. Marginal bone levels, technical parameters, and esthetic outcomes were measured at the implants. At the 6‐month follow‐up, a microbiological test was performed and a soft tissue biopsy was harvested at the implants for histological analysis. Inflammatory cells and fibroblasts/‐cytes were analyzed at the level of the sulcular epithelium, junctional epithelium, and connective tissue. The histological parameters were analyzed by means of a linear mixed model.ResultsThirty‐three patients completed the study, and implant and crown survival rates were 100% at 6 months. Histologically, the number of inflammatory cells tended to be higher in group CEM (p > 0.05). Moreover, significantly less inflammatory cells and fibroblasts/‐cytes were found in the sulcular epithelium compared to the junctional epithelium and supracrestal connective tissue (p < 0.001). Four patients were tested positive for periodontal marker pathogens at the 6‐month follow‐up, and three of them belonged to group CEM. From crown insertion to the 6‐month follow‐up, median marginal bone levels changed only minimally and measured 0.31 and 0.32 mm in group CEM and 0.47 and 0.36 mm in group SCREW, respectively. Clinical and esthetic parameters remained stable over time and were comparable between natural teeth and implants as well as between the groups.ConclusionsCemented reconstructions were associated with more inflammatory cells, and more patients were diagnosed with periodonto‐pathogens. Both types of reconstructions resulted in similar radiological (marginal bone levels) and clinical outcomes (bleeding on probing and probing depth).
Utility of CD30, Ki‐67, and p53 in assisting with the diagnosis of mycosis fungoides with large cell transformation
Authors: Raghavan Shyam S. , Hong Eric K. , Kim Youn H. , Kim Jinah 
Published: October 2018

IntroductionMycosis fungoides (MF) with large cell transformation (LCT) is an advanced stage of cutaneous lymphoma with a poor prognosis. Identification of LCT is critical and especially challenging when the number of large abnormal lymphocytes is near but below 25%. We propose that Ki‐67 and p53 may be useful in making this diagnosis.MethodsWe identified 17 patients with advanced stage (T3 or T4) MF without LCT and 38 patients with a biopsy‐confirmed new diagnosis of MF with LCT treated at our institution's cutaneous lymphoma clinic from 2012 to 2016. Seventeen patients underwent 22 biopsies with advanced stage MF (control), and 38 patients with 46 biopsies of MF with LCT were included in this study.ResultsThe MF cohort had an average CD30 expression of 4%, while the MF‐LCT cohort had an average CD30 expression of 22% (P < 0.05). The MF cohort had an average Ki‐67 staining of 13%, while the MF‐LCT group had an average Ki‐67 staining of 57% (P < 0.05). Forty‐seven percent of the MF‐LCT group was positive for p53; on the other hand, none of the MF control group showed increased p53 expression (P < 0.05).DiscussionWhile CD30 shows some value in delineating large cell transformation, Ki‐67 and p53 appear to be useful immunohistochemical markers in the diagnosis of LCT.
Comparative risk of major bleeding with rivaroxaban and warfarin: Population‐based cohort study of unprovoked venous thromboembolism
Authors: Kohn Christine G. , Bunz Thomas J. , Beyer‐Westendorf Jan , Coleman Craig I. 
Published: October 2018

AbstractObjectivesTo assess the association between rivaroxaban and warfarin and major bleeding risk in unprovoked venous thromboembolism (VTE) patients.MethodsUsing US MarketScan claims from 1/2012‐12/2016, we identified patients who had ≥1 primary hospitalization/emergency department visit diagnosis code for an unprovoked VTE, newly initiated on rivaroxaban or warfarin within 30 days after the VTE and ≥12 months of insurance coverage prior to the VTE. Differences in baseline covariates were adjusted using inverse‐probability‐of‐treatment weights based on propensity scores (residual absolute standardized differences <0.1 achieved for all covariates). Endpoints included any major, gastrointestinal, genitourinary, intracranial, and other bleeds. Patients were followed for up to 12 months or until endpoint occurrence, index oral anticoagulant discontinuation/switch, insurance disenrollment or end of follow‐up.ResultsWe identified 10 489 rivaroxaban and 26 364 warfarin patients with an unprovoked VTE. Upon Cox regression, rivaroxaban reduced patients’ hazard of major bleeding by 27% (95% confidence interval [CI] = 8%‐42%), gastrointestinal bleeding by 38% (95% CI = 14%‐55%), and intracranial hemorrhage by 81% (95% CI = 41%‐99%) vs warfarin. No subtype of major bleeding occurred statistically more often in rivaroxaban vs warfarin‐treated patients.ConclusionsRivaroxaban was associated with a reduced risk of overall, gastrointestinal, and intracranial major bleeding vs warfarin in unprovoked VTE. No bleeding subtype was significantly more frequent in rivaroxaban patients.
Effect of noise and reverberation on speech recognition and listening effort for older adults
Authors: Kwak Chanbeom , Han Woojae , Lee Jihyeon , Kim Jinsook , Kim Sungkyun 
Published: October 2018

AimThe purpose of the present study was to evaluate the speech recognition ability and degree of listening effort for older adults in noisy and reverberating environments.MethodsA total of 80 participants (40 older and 40 younger adults) participated in a sentence recognition test under 20 conditions with four levels of background noise and five levels of reverberation time. In each condition, the degree of listening effort was self‐reported using a 5‐point Likert scale.ResultsThe older and younger groups showed that both the error percentage of the sentence recognition task and scale of the listening effort increased as the background noise and reverberation time increased. In the sentence recognition task, the older group was more affected by the reverberation condition than the noisy background compared with their younger counterparts. For the listening effort, the older group had higher scales than the younger group in all conditions, thereby explaining that they required significant effort during the listening task.ConclusionsThe older adults had poorer speech perception ability and required more listening effort than their younger counterparts in all conditions. Reverberation reversely significantly affected the speech recognition and listening effort for the older adults when compared with the background noise, suggesting that an appropriate level of noise and reverberation should be considered for comfort and a less stressful listening environment for the older adult population. Geriatr Gerontol Int 2018; 18: 1603–1608.
People's history of climate change
Authors: Das Pallavi V. 
Published: October 2018

AbstractWhile social scientific studies have provided useful insights into the phenomenon of climate change, they, however, do not take a historical approach to the impacts of climate change, and people's perception of it. Historians have studied climate and its impact on the whole society but have neglected the everyday experiences and perceptions of climate change within a society such as ordinary people versus the elite perceptions, men versus women's experiences of climate change. Moreover, historians of climate have largely dealt with natural climate change in the distant past, but not with climate change caused by human activities. Since climate change that the world is witnessing in the past century is largely anthropogenic, historians therefore cannot neglect present‐day climate change and its impact on society. Furthermore, although climate change is a global environmental phenomenon, the poor and the marginalized social groups are vulnerable to the impacts of climate change more than others. Hence, climate change and the history of climate change needs to be understood from the perspective of these vulnerable groups in a society. I would, therefore, like to propose a new approach to doing history: people's history of climate change, which will be elaborated in this article.
The relationship between breaking force and hydrophobic interactions or disulfide bonds involved in heat‐induced soy protein gels as affected by heating time and temperature
Authors: Wu Chao , Ma Wuchao , Hua Yufei 
Published: October 2018

SummaryHydrophobic interactions and disulfide bonds involved in heat‐induced soy protein gels were characterised by determining the dissolution kinetics of gels. Reducing SDS‐PAGE results revealed that all proteins in gel network could be dissolved simultaneously by 1% (w/v) SDS solution, while a majority of glycinin (11S) A polypeptide and a moderate amount of 11S‐B polypeptides, 7S‐α′, α, γ, and β subunits were found in 2% (w/v) DTT dissolving samples. Stronger interaction force between proteins in gel network would result in lower dissolution constant rate. The breaking force of soy gels increased from 543 to 2171 gforce with increasing heating temperature from 85 to 100 °C, and denaturation of 11S globulins played an important role in the development of gel network. As increasing heating time from 30 to 120 min, the breaking force of gels increased from 1687 to 2175 gforce, then decreased to 1253 gforce when the time was prolonged to 240 min. Negative correlations were observed between breaking force and dissolution constant rate kSDS or Δk, which suggested that the strengthening of both hydrophobic interactions and disulfide bonds.
The role of platelet hyperreactivity in venous thromboembolism after total knee arthroplasty in elderly population without pharmacologic prophylaxis: A single‐center study
Authors: Kim Youngmo , Park Youngcheol , Joo Yongbum , Kim Seon Young , Kim Jimyung 
Published: October 2018

AbstractIntroductionWhile it is suggested that platelet hyperreactivity plays a role in the arterial thrombi, its link with venous thromboembolism (VTE) is not well defined. Aggregometry using low concentrations of agonists is proposed as a reliable method to detect hyperreactivity. The aim of this study was to examine whether platelet hyperreactivity affects the development of VTE after total knee arthroplasty (TKA).MethodsTotal 150 elderly patients without VTE history were enrolled. Mechanical prophylaxis was used for VTE after TKA. We performed platelet aggregation using Chrono‐log (Chrono‐log Corporation, USA) in the presence of low concentrations of ADP (1.0 μmol/L) and epinephrine (0.4, 1.0 μmol/L), and measured maximal aggregation (%).ResultsAt 0.4 μmol/L epinephrine, 69.3%, 15.3%, and 15.3% displayed low (<40%), moderate (40‐60%), and high (>60%) levels of aggregation, respectively. The proportion of high level of aggregation was 36.7%, 30.7% at 1.0 μmol/L of epinephrine and ADP, respectively. The incidence of VTE was higher in the moderate/high aggregation group (10/46, 21.7%) than in the low aggregation group (1/104, 1.0%) at 0.4 μmol/L epinephrine (P < 0.0001). In predicting postoperative VTE, sensitivity and specificity of ≥40% aggregation at 0.4 μmol/L epinephrine were 90.9% and 74.1%. Higher mean platelet volume and lower volume of blood loss were seen in the high aggregation group than in the low aggregation group.ConclusionAggregation response to 0.4 μmol/L epinephrine is an optimal assay to classify platelet activity. Platelet hyperreactivity may increase the risk of postoperative VTE in an elderly population, and can be an indication of pharmacologic prophylaxis.
Les déterminants du chômage des jeunes en Europe: facteurs économiques et autres causes
Authors: TOMIĆ Iva 
Published: October 2018

RésuméL'auteure recherche les déterminants du chômage des jeunes en Europe entre 2002 et 2014 en estimant des modèles sur données de panel pour les 28 États membres de l'UE. Face à l'hétérogénéité entre les pays, elle constitue deux souséchantillons (groupes «taux élevé» et «taux faible»), selon le niveau de chômage. L'analyse permet d'associer le chômage des jeunes à une faible croissance du PIB, un faible poids du secteur de la construction et une dette publique élevée. Parmi les autres déterminants importants figurent la faible mobilité résidentielle (pour cause de propriété du logement), la corruption, les transferts de fonds et la résidence au domicile parental.
El Convenio núm. 189 de la OIT en la Argentina, Chile y Paraguay. Estudio comparado de la regulación del tiempo de trabajo y de la remuneración de las trabajadoras domésticas
Authors: POBLETE Lorena 
Published: October 2018

ResumenEn junio de 2011, la Conferencia Internacional del Trabajo adoptó el Convenio núm. 189 sobre el trabajo decente para las trabajadoras y los trabajadores domésticos y su Recomendación núm. 201 asociada. Desde una perspectiva de derecho comparado, este artículo analiza el rol del Convenio en las reformas legislativas de tres países latinoamericanos que lo ratificaron –Argentina, Chile y Paraguay–, centrándose en los debates y controversias que explican cómo sus disposiciones relativas al tiempo de trabajo y a la remuneración fueron incorporadas en las legislaciones nacionales sobre trabajo doméstico remunerado en esos tres países.
Gendered Transnational Ties and Multipolar Economies: Chinese Migrant Women's WeChat Commerce in Taiwan
Authors: Zani Beatrice 
Published: October 2018

AbstractAfter a first migration in internal China, Chinese migrant women re‐migrate to Taiwan through marriage. There, to cope with economic discrimination, by exploiting the social networkWeChat, Chinese women produce physical and virtual transnational multipolar economies, connecting the society of departure, China, and of settlement, Taiwan. Engaging with the contemporary debate about migrants’ translocal practices and economic transnationalism, this research article aims at elucidating the link between migration and entrepreneurship, through the case of Chinese migrant women's physical and virtual entrepreneurial activities across the Taiwan Strait. It explores the development of a specific culture of migration and of affections during the two mobility experiences, and the creation of gendered transnational networks across the borders. Thus, it provides empirical data for an understanding of Chinese women's cross‐strait migration in terms of interconnection, circulation and simultaneity.