bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular characterization of Hysterothylacium aduncum (Nematoda: Raphidascarididae) larvae infecting Merlangius merlangus euxinus (Linnaeus, 1758) from the Turkish Black Sea coast based on mitochondrial small subunit ribosomal RNA gene analysis
Authors: PEKMEZCİ Gökmen Zafer 
Published: July 2019

The taxonomy of Hysterothylacium
genus remains incomplete and unclear in Turkish waters. In the present study, H. adumcum larvae were morphologically identified
from Merlangius merlangus euxinus in
the Black Sea, Turkey. The
nuclear ribosomal ITS regions (ITS-1, 5.8S subunit, ITS-2) and the small
subunit of the mitochondrial ribosomal RNA (rrnS) gene of H. aduncum were amplified and sequenced. The BLAST analysis indicated
that present ITS sequences of H. aduncum
were identical to that of the reference sequence of H. aduncum (accession no JX413596) recorded previously from the Black
Sea, Turkey. The present rrnS gene of H.
aduncum from the Black Sea, Turkey (MK886768) showed 97.94 to 99.56%
identity with isolates of H. aduncum
from the Mediterranean Sea (MF000685-MF000691) and the Chinese waters
(MF140344). Moreover, pairwise comparison between the rrnS sequences of the H. aduncum from the Black Sea, Turkey (MK886768)
and others H. aduncum isolates from
the Mediterranean Sea (MF000685-MF000691), the Chinese waters (MF140344) showed
differences ranged from 0.2 and 1.7%. With
the present study, H. aduncum from the Black Sea was characterized for
the first time by sequencing of the mitochondrial rrnS gene.
A Model for Energy Buildup and Eruption Onset in Coronal Mass Ejections
Authors: Dahlin J. T. , Antiochos S. K. , DeVore C. R. 
Published: July 2019

Abstract
Coronal mass ejections (CMEs) and eruptive flares (EFs) are the most energetic explosions in the solar system. Their underlying origin is the free energy that builds up slowly in the sheared magnetic field of a filament channel. We report the first end-to-end numerical simulation of a CME/EF, from zero-free-energy initial state through filament channel formation to violent eruption, driven solely by the magnetic-helicity condensation process. Helicity is the topological measure of linkages between magnetic flux systems, and is conserved in the corona, building up inexorably until it is ejected into interplanetary space. Numerous investigations have demonstrated that helicity injected by small-scale vortical motions, such as those observed in the photosphere, undergoes an inverse cascade from small scales to large, “condensing” at magnetic-polarity boundaries. Our new results verify that this process forms a filament channel within a compact bipolar region embedded in a background dipole field, and show for the first time that a fast CME eventually occurs via the magnetic-breakout mechanism. We further show that the trigger for explosive eruption is reconnection onset in the flare current sheet that develops above the polarity inversion line: this reconnection forms flare loops below the sheet and a CME flux rope above, and initiates high-speed outward flow of the CME. Our findings have important implications for magnetic self-organization and explosive behavior in solar and other astrophysical plasmas, as well as for understanding and predicting explosive solar activity.
Detection of Continuum Submillimeter Emission Associated with Candidate Protoplanets
Authors: Isella Andrea , Benisty Myriam , Teague Richard , Bae Jaehan , Keppler Miriam , Facchini Stefano , Pérez Laura 
Published: July 2019

Abstract
We present the discovery of a spatially unresolved source of submillimeter continuum emission (λ = 855 μm) associated with a young planet, PDS 70 c, recently detected in Hα emission around the 5 Myr old T Tauri star PDS 70. We interpret the emission as originating from a dusty circumplanetary disk with a dust mass between 2 × 10−3
M
⊕ and 4.2 × 10−3
M
⊕. Assuming a standard gas-to-dust ratio of 100, the ratio between the total mass of the circumplanetary disk and the mass of the central planet would be between 10−4 and 10−5. Furthermore, we report the discovery of another compact continuum source located 0.″074 ± 0.″013 southwest of a second known planet in this system, PDS 70 b, that was previously detected in near-infrared images. We speculate that the latter source might trace dust orbiting in proximity of the planet, but more sensitive observations are required to unveil its nature.
Taxonomic revision of the Neotropical genus Rhabdotylus Lutz, 1913 (Diptera: Tabanidae)
Authors: Turcatel Mauren 
Published: July 2019

Here I revise the Neotropical genusRhabdotylusLutz, 1913 (Tabaninae: Diachlorini), including redescription of three species that range from Guatemala to Argentina:Rhabdotylusrubrum(Thunberg, 1827),Rhabdotylusvenenatum(Osten Sacken, 1886), andRhabdotylusviridiventris(Macquart, 1838).Rhabdotylusplaniventris(Wiedemann, 1828) is established as a junior synonym ofR.rubrum, syn. nov. A dichotomous identification key based on external morphological characters is provided.
World Flora Online (WFO) - Quality control workflow for an evolving taxonomic backbone
Authors: Palese Raoul , Boillat Cyril , Loizeau Pierre-André 
Published: July 2019

Initially populated with information gathered from The Plant List, the WFO’s taxonomic backbone will be augmented and modernized by newer taxonomic sources delivered by global plant Taxonomic Expert Networks (TENs). At the same time, descriptive data from floras, such as text descriptions, images, geographic distributions, keys, and trait data will be linked to this evolving taxonomic backbone. Semi-automated workflows have to be built to efficiently pull together the work of the TENs and digital floras and monographs into a single source: the WFO portal.
These semi-automated workflows will have to ensure multiple functionalities: format check of the data submitted by the different backbone data providers (TENs or descriptive data providers), integrity and quality checks of the data provided, comparison of these data with the current WFO’s taxonomic backbone (matching with the WFO ID’s and with the names, check at the level of the family and the taxonomic status attribution, etc.). Applications will also be developed as Decision Making Helper for the TENs: thanks to these applications, TENs will be able to make decisions concerning the resolution of names not present in the current backbone or on the questions of conflicts at the level of the belonging to a family or the taxonomic status for a proposed name.
At the end of these processes, new versions of the taxonomic backbone will regularly be delivered to be integrated into the WFO portal.
Représentations du handicap dans les organisations de personnes aînées : conditions et limites de l’inclusion
Authors: Raymond Émilie , Lantagne Lopez Mélanie 
Published: July 2019

Bien que la participation sociale des aînés ait fait l’objet d’une attention soutenue, les connaissances sur les réalités des personnes aînées ayant des incapacités en matière de participation sont encore limitées. Il est pressant de se pencher sur les manières de mieux encourager leur inclusion dans la vie collective, notamment par le biais de milieux associatifs plus accueillants. Formées d’opinions socialement construites relativement à un objet donné, les représentations sociales du handicap apparaissent susceptibles de soutenir ou encore de freiner la participation sociale des personnes aînées ayant des incapacités. L’article a pour objectif de documenter les représentations sociales existant dans les milieux associatifs d’aînés à l’égard de la participation de ce groupe. Utilisant une méthode de recherche mixte, un devis séquentiel exploratoire a été mené, dans lequel une première phase qualitative a permis de réaliser 4 groupes de discussion, tandis qu’une deuxième phase quantitative a consisté en un questionnaire administré à 86 répondants. Les résultats sont présentés selon les quatre fonctions des représentations sociales, soit les fonctions 1) de savoir, 2) identitaires, 3) d’orientation, et 4) justificatrices. L’interprétation des résultats suggère des balises pour déconstruire et modifier les aspects représentationnels défavorables à l’inclusion.
Understanding the Level of Self-Directed Learning and Decision-Making Style of Construction-Related Workers
Authors: Mohd Norhazren Izatie , Ali Kherun Nita , Ebrahimi Shirin Shafiei , Ahmad Fauzi Ahmad Faiz Azizi 
Published: July 2019

<p class="0abstract">Current serious game framework still lacks in fulfilling the user's requirements. This is due to the framework elements which only focus on the process of delivery. Hence, this study was carried out to determine user’s ability in self-directed learning and their styles in making a decision. This study forms part of a larger research on a framework for serious game frameworks for hazard identification training modules. A set of questionnaire consisting of three sections which are demographic, decision-making styles and levels of self-directed learning was designed. In decision-making styles, 49 items are measured representing eight styles in decision making such as vigilant, dependent, avoidant, anxious, confident, spontaneous, brooding and intuitive. Meanwhile, a self-rating scale consisting of 50 items was used to measure the level of self-directed learning such as awareness, learning strategies, learning activities, evaluation and interpersonal skills. Data was collected from 319 construction-related workers and analysed using mean comparison and ANOVA. Findings confirmed that their style of decision-making is inclined to ‘vigilant’ and ‘brooding’ types. The results revealed two levels of self-directed learning, namely, the moderate level for supervisor and high level for general workers, skilled workers, consultants, management teams and safety trainees. This level of self-directed learning is influenced by their level of education and working experiences. The findings also highlight that decision-making style has a moderate relationship with the level of self-directed learning among construction-related workers. The study contributes to the understanding of the construction workers' needs in enhancing their skills in becoming independent and lifelong learners</p>
BET Bromodomain Inhibition Suppresses Human T Cell Function
Authors: Georgiev Peter , Wang Yun , Muise Eric S , Bandi Madhavi L , Blumenschein Wendy , Sathe Manjiri , Pinheiro Elaine M , Shumway Stuart D 
Published: July 2019

Abstract
Bromodomain and extraterminal domain (BET) proteins help direct the differentiation of helper T cell subsets, but their role in activated T cell function has not been described in detail. In this study, we investigate various consequences of epigenetic perturbation in human T lymphocytes using MK-8628, a potent and highly selective inhibitor of BET proteins. MK-8628 reduces the expression of canonical transcripts directing the proliferation, activation, and effector function of T lymphocytes. Treatment with MK-8628 abolishes the expression of key cyclins required for cell cycle progression and induces G1 cell cycle arrest in TCR-activated lymphocytes. This antiproliferative phenotype partially results from T lymphocyte apoptosis, which is exacerbated by MK-8628. In naive and memory T cell subsets, MK-8628 antagonizes T cell activation and suppresses polyfunctional cytokine production. Collectively, our results describe potent immunosuppressive effects of BET inhibition on human T cell biology. These results have important implications for immune modulatory targeting of BET proteins in the settings of T cell–driven autoimmune inflammation.
A retrospective case series of 12 patients with chronic reactive arthritis with emphasis on treatment outcome with biologics
Authors: Gupta Vishal , Mohta Pratik , Sharma Vinod Kumar , Khanna Neena 
Published: July 2019

Background:
Patients with reactive arthritis frequently present to dermatologists. However, there is paucity of information regarding its clinical aspects and management in dermatological literature.

Objective:
To review the clinical features and management of patients with chronic reactive arthritis admitted to the dermatology department of a teaching hospital.

Methods:
This was a retrospective analysis of patients with reactive arthritis admitted to the Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India from January 2016 to February 2018.

Results:
There were 12 males (disease duration 9–180 months). Biologics were used in 9 (75%) patients on 16 different occasions, the most frequent being infliximab (n = 10 times), followed by adalimumab (n = 3), etanercept, secukinumab and itolizumab (n = 1 each), in combination with other systemic agents. Response rate with treatment regimens including biologics (69% responders, 31% partial responders) was statistically significantly better than those without biologics (27% responders, 46% partial responders, 27% nonresponders; P = 0.036), using a composite measure assessing improvement in skin and joint symptoms. Biologics were discontinued on 50% of the occasions, after a median of 3.5 months (range 1.5–7.5 months) because of satisfactory response (n = 4), therapeutic fatigue (n = 3) or adverse event (n = 1). After biologic discontinuation, the response was sustained for a median of 5 months (range 3–6 months) before disease exacerbation. The number of treatment switches increased with the follow-up duration (median three switches per patient, range 1–8). The median follow-up duration was 10.5 months (range 4–76 months).

Conclusion:
Biologics produce rapid improvement in skin and joint symptoms in chronic reactive arthritis, but the response is not long-lasting. Patients with chronic reactive arthritis have a waxing and waning course despite regular treatment.

Limitations:
The limitations are retrospective design, small sample size and lack of a validated outcome measure.
Technical Aspects of Addressing Multiligament Knee Instability
Authors: Dekker Travis J , Guerrero Evan M 
Published: July 2019

ABSTRACT
Multiligament Knee Injuries (MLKI) are rare but devastating injuries that require both acute and chronic management. These injuries necessitate operative management with individual patient factors dictating management in an acute (<6 weeks) versus chronic (>6 weeks) time frame. Anterior cruciate ligament, posterior cruciate ligament and posterolateral corner reconstruction remains the gold standard for operative management while most medial collateral ligament injuries can be managed non-operatively. Graft fixation sequence is essential in re-tensioning the soft tissues to allow for a functional and balanced knee post-operatively- the PCL is first fixed in flexion, followed by the ACL in extension, and then lastly, the PLC and MCL are addressed as needed. This review paper highlights technical considerations demonstrated in two case reports to include timing of surgery, graft selection and sequence of graft fixation.
Dekker TJ, Kildow BJ, Guerrero EM, Moorman CT III. Technical Aspects of Addressing Multiligament Knee Instability. The Duke Orthop J 2016;6(1):47-53.
Microbiological Profile in Endodontic-periodontal Lesion
Authors: Nainar Deepavalli Arumuga , Alamelu Swarna , KV Arun 
Published: July 2019

ABSTRACT
Endodontic-periodontal lesion is a clinical manifestation of the pathologic intercommunication between pulpal and periodontal tissues. In general, these lesions are multifaceted in nature and can have a varied pathogenesis. Fundamental to our understanding of the pulpoperiodontal lesions is the key role of the pathogenic ecosystem that exists within this complex structure. Evidence suggests that there exists a wide range of microbial species in the periapical and periodontal tissues and that their concurrent pathogenesis is constantly linked to the bacterial interrelations between the two tissue types. Understanding the microbial involvement is of utmost significance as it offers a rationale for differential diagnosis and subsequent management of such lesions. This review has attempted to provide a basic insight on the microbiome or the microbial flora entailed in the bidirectional pathogenesis of endodontic-periodontal lesions.

How to cite this article
Rajasekaran M, Nainar DA, Alamelu S, KV Arun. Microbiological Profile in Endodontic-periodontal Lesion. J Oper Dent Endod 2016;1(1):25-29.
Nasolabial Flap in the Management of Oral Submucous Fibrosis
Authors: Jamdade Vaishali , LNU Amit 
Published: July 2019

ABSTRACT
Oral submucous fibrosis (OSMF) is a premalignant condition associated with restricted mouth opening. Oral submucous fibrosis is poorly understood and unsatisfactorily treated disease. Serious complication is the risk of development of oral carcinoma. Different treatment modalities like medical, surgical, physical therapy or combination are used to improve the condition of the patient. Surgical treatment is usually indicated in late and irreversible stage of the disease. Successful use of nasolabial flap in the management of OSMF is presented.

How to cite this article
Jamdade V, Sharma S, Chitlangia P, Amit. Nasolabial Flap in the Management of Oral Submucous Fibrosis. J Mahatma Gandhi Univ Med Sci Tech 2016;1(1):27-29.
Hemisection: A Savior for Hopeless Teeth
Authors: Mittal Prachi , LNU Amit, , Mehta Purav , Khurana Deeksha 
Published: July 2019

ABSTRACT
Hemisection refers to the sectioning of a molar tooth with the removal of unrestorable root (along with the crown part) which maybe affected by periodontal, endodontic, structural (cracked roots), or caries. The treatment strategy involves a combined periodontal, endodontic and prosthodontic assessment and evaluation because in hemisection, like any other treatment, appropriate case selection is the most important factor determining the long-term success.

How to cite this article
Mittal P, Prasad AB, Raisingani D, Amit, Mehta P, Soni D, Khurana D. Hemisection: A Savior for Hopeless Teeth. J Mahatma Gandhi Univ Med Sci Tech 2016;1(1):30-34.
Extranodal Large B-Cell Type Aggressive Non-Hodgkin's Lymphoma
Authors: Gupta Sonal , Gumber Parvind 
Published: July 2019

ABSTRACT
Non-Hodgkin's lymphomas belongs to a group of neoplasm, originate from the cells of lymphoreticular system that shows diversity in manner of presentation, response to therapy and prognosis. Non-Hodgkin's lymphoma accounts for 80—90% of all lymphomas. Though primary intraoral lesion in non- Hodgkin's lymphoma are uncommon, it is important to be aware of them since intraoral manifestation are presenting symptom in these patients. A 72-year-old Indian male presented with complaint of asymptomatic swelling in the left side of face since one and half months. A careful clinical evaluation supported by radiologic, histopathologic and immunohistochemical investigations will help in identifying the disease at an early stage, which will result in better prognosis.

How to cite this article
Gupta S, Gumber P. Extranodal Large B-Cell Type Aggressive Non-Hodgkin's Lymphoma. J Mahatma Gandhi Univ Med Sci Tech 2016;1(2):71-74.
Acute Dissection of the Ascending Aorta: A Case Report and Topic Review
Authors: Chishti MA , Rawat Vivek , Nagarwal P 
Published: July 2019

ABSTRACTAortic dissection (AD) is a rare entity with an incidence estimated to be 5 to 30 cases per million people per year1 (The Gale Encyclopedia of Medicine, 3rd ed.). It has association with hypertension, connective tissue disorders, congenital aortic stenosis, and bicuspid aortic valve. Spontaneous dissections are rare. It has a high mortality rate when left untreated. Recent advances in imaging have allowed for early and accurate diagnosis of acute aortic syndromes and the options for management are expanding. This case report and review presents the case of a 20-year-old man with Marfan's syndrome with acute type I AD who underwent emergency Bentall's procedure.How to cite this articleChishti MA, Rawat V, Nagarwal P. Acute Dissection of the Ascending Aorta: A Case Report and Topic Review. J Mahatma Gandhi Univ Med Sci Tech 2017;2(1):31-34.
Management of an Impacted Dilacerated Permanent Maxillary Central Incisor
Authors: Goenka Puneet , Agarwal Swati , Lakshmi Vijay , Chaturvedi Yogita , Nirwan Mitakshara 
Published: July 2019

ABSTRACTThe impacted maxillary incisor is rare and detrimental for problems related to esthetics and occlusion in permanent dentition stage. The diagnosis of an impacted incisor with dilaceration refers to a dental deformity characterized by an angulation between the crown and the root, causing noneruption of the incisor. The most common cause of dilaceration in a tooth is trauma to its primary predecessor like avulsions, intrusions, or gross displacement of primary incisors. This study presents a case with overretained mobile deciduous teeth that were diagnosed radiographically with an impacted dilacerated maxillary central incisor surrounded by a large radiolucency. History of trauma to the same region was given at the age of 1 year. On examination, multiple missing permanent teeth were noted. The management of the case was carried out by surgical enucleation and histopathologic examination confirmed diagnosis of an infected dentigerous cyst.How to cite this articleAgarwal S, Goenka P, Lakshmi V, Chaturvedi Y, Nirwan M. Management of an Impacted Dilacerated Permanent Maxillary Central Incisor. J Mahatma Gandhi Univ Med Sci Tech 2017;2(1):44-46.
Empathie, taboe en erkenning van tragiek
Authors: Lemmens Willem 
Published: July 2019

Ik ben dankbaar dat 12 collega’s met elk een specifieke expertise in de problematiek de moeite namen om mijn beschouwing over empathie en euthanasie in de psychiatrie met een kritisch oog te lezen en van commentaar te voorzien. Graag grijp ik de geboden kans om enkele kanttekeningen te plaatsen of verduidelijkingen te bieden bij deze commentaren. Mijn bedoeling is, vooreerst, om op die manier de insteek van mijn artikel en de centrale stellingen die ik verdedig verder toe te lichten: soms lijk ik immers verkeerd te zijn begrepen of was ik wellicht niet helder genoeg. Daarnaast wil ik mijn gekende kritiek op de huidige legale en juridische regulering van euthanasie in de psychiatrie duidelijker motiveren.
Op alle commentaren afzonderlijk antwoorden, leek me ondoenbaar en zou te ver voeren. Ik heb daarom een selectie gemaakt van een aantal cruciale bedenkingen die in meerdere bijdragen opdoken: ik hoop op die manier samen met mijn respondenten een bijdrage te leveren aan een maatschappelijk uiterst belangrijke discussie die, zoals één van de respondenten opmerkt, dringend nood heeft aan meer diepgang.