bluuebunny/crossref_metadata_2025_split huggingface dataset:
Yahudiliğin Tek İbadet Merkezi Kudüs müydü?
Authors: AYKIT Dursun Ali , YETİM Merve 
Published: October 2019

Günümüz Yahudilik anlayışı bize Süleyman Tapınağının dolayısıyla Kudüs’ün daima merkezde olduğunu, hiçbir dönemde bundan başka bir ibadet yerinin kabul edilmediğini iddia etmektedir. Fakat erken dönem Yahudi tarihine bakıldığı takdirde birden fazla ibadet mekanları ile karşılaşılmaktadır. Yüksek yerler (İbranice bamot) adı verilen bu ibadet mekanları erken dönemlerde atalar, hakimler ve krallar da dahil olmak üzere tüm İsrailoğullarının ibadet ettikleri mekanlardır. Fakat Babil sürgünü sonrasında insanlar Kudüs’e döndüler ve buradaki tapınak etrafında kenetlenmeye başladılar. İşte bu noktada Kadim İsrail, Krallığın ikiye ayrılması, Kuzey İsrail Krallığının yıkılması, Yoşiya’nın reformu ve Babil sürgünü sonrası olarak beş aşamaya ayırdığımız bu tarihsel süreçler, ibadet yerlerinde geçirilen dönüşümü gözler önüne serecektir. Bu bağlamda iddia edildiği gibi Kudüs’ün ilk dönemlerde ibadet için bir merkeziliği söz konusu değildir.
Oral Care Evaluation to Prevent Oral Mucositis in Estrogen Receptor-Positive Metastatic Breast Cancer Patients Treated with Everolimus (Oral Care-BC): A Randomized Controlled Phase III Trial
Authors: Niikura Naoki , Nakatukasa Katsuhiko , Amemiya Takeshi , Watanabe Ken-ichi , Hata Hironobu , Kikawa Yuichiro , Taniike Naoki , Yamanaka Takashi , Mitsunaga Sachiyo , Nakagami Kazuhiko , Adachi Moriyasu , Kondo Naoto , Shibuya Yasuyuki , Hayashi Naoki , Naito Mariko , Kashiwabara Kosuke , Yamashita Toshinari , Umeda Masahiro , Mukai Hirofumi , Ota Yoshihide 
Published: October 2019

Abstract

Background
The incidence of oral mucositis (any grade) after everolimus treatment is 58% in the general population and 81% in Asian patients. This study hypothesized that professional oral care (POC) before everolimus treatment could reduce the incidence of everolimus-induced oral mucositis.

Materials and Methods
This randomized, multicenter, open-label, phase III study evaluated the efficacy of POC in preventing everolimus-induced mucositis. Patients were randomized into POC and control groups (1:1 ratio) and received everolimus with exemestane. Patients in the POC group underwent teeth surface cleaning, scaling, and tongue cleaning before everolimus initiation and continued to receive weekly POC throughout the 8-week treatment period. Patients in the control group brushed their own teeth and gargled with 0.9% sodium chloride solution or water. The primary endpoint was the incidence of all grades of oral mucositis. We targeted acquisition of 200 patients with a 2-sided type I error rate of 5% and 80% power to detect 25% risk reduction.

Results
Between March 2015 and December 2017, we enrolled 175 women from 31 institutions, of which five did not receive the protocol treatment and were excluded. Over the 8 weeks, the incidence of grade 1 oral mucositis was significantly different between the POC group (76.5%, 62 of 82 patients) and control group (89.7%, 78 of 87 patients; p = .034). The incidence of grade 2 (severe) oral mucositis was also significantly different between the POC group (34.6%, 28 of 82 patients) and control group (54%, 47 of 87 patients; p = .015). As a result of oral mucositis, 18 (22.0%) patients in the POC group and 28 (32.2%) in the control group had to undergo everolimus dose reduction.

Conclusion
POC reduced the incidence and severity of oral mucositis in patients receiving everolimus and exemestane. This might be considered as a treatment option of oral care for patients undergoing this treatment. Clinical trial identification number: NCT 02069093.
Городское движение и планировка городов
Authors: Блинкин Михаил Яковлевич , Воробьев Антон Николаевич 
Published: October 2019

Статья посвящена анализу трудов Алексея Александровича Полякова, известного отечественного урбаниста, чьи основные публикации пришлись на период 1953–1967 гг. и во многом, даже с учетом идеологических ограничений, являлись передовыми для советского транспортного планирования. Авторы, учитывая идеологический контекст, выявляют основные идеи его исследований, сопоставляя их с трудами современников и проецируя посредством математического аппарата на современные реалии. В статье рассматриваются ключевые вопросы отечественной транспортной науки в советский период: процент территории, приходящийся на улицы, возможности (предложение) улично-дорожной сети (УДС) в городах, максимально возможный объем дорожного движения, структура УДС, ее непрямолинейность и контуры, модальная структура (modal split), развитие общественного транспорта. Оцениваются предложения А.А. Полякова и выявляются основные причины, не позволившие реализовать эти предложения в полном объеме. Особое внимание при этом уделяется влиянию взрывной автомобилизации, произошедшей в России в последнем десятилетии XX в.
Статья носит проблематизационный характер. В ней выявляются существующие проблемы в современной отечественной транспортной науке, в том числе проблема учета научного знания при принятии управленческих решений.
Long-term Survival after Aortic Valve Replacement with the Mitroflow Bioprosthesis: a Comparative Study
Authors: Manché Alexander , Camilleri Liberato 
Published: October 2019

Background Recent case reports of early structural degeneration of the Mitroflow valve have cast doubts on the suitability of this bioprosthesis, particularly in the smaller sizes, and in younger patients. We studied long-term patient survival, in a comparative study, as a marker of success after aortic valve replacement.Methods Long-term survival in 142 consecutive patients implanted with the Mitroflow valve was compared, using the Kaplan-Meier method, with a control group of 149 patients receiving different bioprostheses. Ninety two percent of patients were over 70 and the Mitroflow was used preferentially in smaller sizes.Results Long-term survival in patients who received a Mitroflow valve was equivalent to controls. Four documented cases of premature structural valve degeneration (3 Mitroflow, 1 Perimount) required a second intervention.Conclusions The Mitroflow compared favourably with other valves in our practice. Although a few patients required further treatment this had no significant adverse impact on overall survival.
CONCEPT OF THE AUTHOR’S PERSONALITY WITHIN THE FRAMEWORK OF THE IMAGE SYSTEM AND NARRATIVE STRATEGIES OF THE MODERN WRITER (ON THE EXAMPLE OF LUDMILA ULITSKAYA’S PROSE)
Authors: A. M. Martazanov A. M. , Kh. M. Martazanova , A. M. Khusikhanov , E. Kh. Dalieva , T. Kh. Akhmadova 
Published: October 2019

The purpose of the article: The purpose of the article is to identify the peculiarities of the concept of the personality of the author within the framework of the system of images and narrative strategies of the writer (on the example of the prose of Lyudmila Ulitskaya).Materials and methods: The leading approach to the study of this problem is the analysis of key problem issues of the history course.Results of the research: Based on the analysis conducted by the author, it is noted that the personality of the author in the works of Ulitskaya manifests itself both in the form of a biographical personality and in the form of the expression of the author’s perception of the world, and the author does not enter into polemics with her characters and does not give an assessment of either their character or their actions.
Applications: This research can be used for the universities, teachers, and students.
Novelty/Originality: In this research, the model of the concept of the author’s personality within the framework of the imaging system and narrative strategies of the modern writer (on the example of Ludmila Ulitskaya’s prose) is presented in a comprehensive and complete manner.
RESILIENCE AND FLOOD RISK MANAGEMENT IN A COASTAL ZONE
Authors: Isa Muzakar , Sugiyanto FX. , Susilowati Indah 
Published: October 2019

Purpose: The article conducts the study that the northern coast of Central Java province in Indonesia is considered as the critical area of flood path. The region always suffers from floods due to the heavy rain and/or the sea-level rise. Therefore, people are suffering and the ecosystem is deteriorating.
Methodology: Vulnerability and resilience are considered based on the use of indicators. An indicator or a set of indicators can be deﬁned as an inherent characteristic that quantitatively estimates the conditions of a system. They usually focus on minor, feasible, palpable and effective part of a system offering people a sense of bigger representation. Therefore, it is very important to know effects on people, cities and natural resources by these indicators.
Result: Results of the present study indicated that levels of vulnerability and the community resilience of the northern coast of Central Java to flood were in the medium category. In addition, the level of coastal community resilience was affected by the exposure of flood risk programs and the public adaptive capacity variable.
Applications: This research can be used for universities, teachers, and students.
Novelty/Originality: A number of efforts have been made to manage and mitigate the flood problems, despite the fact that results are incomplete and still restructuring from time to time. It is realized that infrastructural capacity for flood control, community awareness, and other multi-factors significantly contribute to solving the flood problem in the regions.
ANALYSIS OF HOUSING FINANCE POLICIES FOR LOW-INCOME COMMUNITY IN WEST BANDUNG, WEST JAVA PROVINCE, INDONESIA
Authors: Suryanto  , Rusli Budiman , Karlina Nina , Candradewini  
Published: October 2019

Purpose of the study: The research aims to analyze the financing of housing construction in West Bandung, West Java Province, Indonesia.
Methodology: The research method used a qualitative approach. Primary data obtained through interview, while secondary data through literature study. The validity of the data obtained from the informants is tested through the triangulation technique. The data analysis technique is done by doing description and analysis of the object under study.
Results: The results show that housing finance policy in West Bandung through advance assistance, interest subsidy, housing financing liquidity facility (FLPP in Indonesia) and direct assistance. Advance payment policies, interest subsidies and FLPP are channeled through banks targeting low-income, bankable communities. The non-bankable community is assisted through the Self-Help Housing Stimulant Stimulation Program from the central government, the Unfit Home Program from the provincial and district governments.
Applications of this study: This research can be used for the universities, teachers, and students.
Clarificação de água superficial com baixos valores de turbidez e cor aparente utilizando extrato de sementes de Moringa oleifera e sulfato de alumínio
Authors: Eguchi Cristina Satomi Yamamoto , Arantes Camila Clementina 
Published: October 2019

No tratamento de água de ciclo completo ou convencional, coagulantes são utilizados para desestabilizar partículas suspensas e dissolvidas presentes na água bruta, propiciando a formação de flocos passíveis de remoção pelo processo de sedimentação. Além dos coagulantes tradicionais, como os sais metálicos à base de alumínio e ferro, há polímeros sintéticos e naturais que podem ser utilizados para tal finalidade, como proteínas presentes em sementes de Moringa oleifera. Este trabalho teve como objetivo comparar o uso do sulfato de alumínio com o extrato de sementes da Moringa oleifera na clarificação de água bruta superficial com baixos valores de turbidez e cor aparente, na faixa de 11 uT e 9 uC, respectivamente. Foram realizados ensaios de coagulação (100 RPM por 1 minuto), floculação (20 RPM por 15 minutos) e sedimentação (30 minutos) em equipamento jar-test utilizando dosagens dos dois coagulantes variando entre 10 a 50 mg L-1 e pH de coagulação igual a 7,0. A dosagem mais eficiente do extrato de sementes de Moringa oleifera foi a de 10 mg L-1, resultando em eficiências abaixo de 45%. Já para dosagens acima de 40 mg L-1 não houve redução para tais parâmetros. O uso do sulfato de alumínio resultou em reduções acima de 85%. Conclui-se que para água bruta com baixos valores de turbidez e cor aparente, submetida às condições aplicadas nesse estudo, o coagulante extraído de sementes de Moringa oleifera não garante reduções satisfatórias como ocorre para o sulfato de alumínio.
Avaliação do shelf life para produtos lácteos nos Estados Unidos da América, Europa e Brasil
Authors: Gonçalves Maria Carolina Gonçalves , Malpass Geoffroy Roger Pointer Malpass , Okura Mônica Hitomi , Granato Ana Claudia 
Published: October 2019

A cadeia de lácteos é um setor produtivo relevante para a economia mundial e que abrange uma vasta parcela de consumidores em todas as faixas etárias. O objetivo deste estudo foi analisar comparativamente as legislações vigentes no Brasil, Estados Unidos e Europa, para leite UHT, queijo mussarelae iogurte batido com relação ao shelf life(vida de prateleira) desses produtos e analisar o impacto que isso causa na cadeia de produtos lácteos no país. Diante disso, pode-se identificar que o Brasil ainda apresenta produtos com um shelf lifemuito aquém dos produtos norte-americanos e europeus. Para que o mercado brasileiro cresça nacional e internacionalmente, investir na qualidade da matéria prima é fundamental para o bom desempenho do produto durante o beneficiamento e, posteriormente, durante o shelf life.
Considerações acerca da relação entre o ciclo hidroclimático e a produção bovina na bacia do Alto Paraguai
Authors: Farias Pedro Cassiano , Girard Pierre 
Published: October 2019

A pecuária bovina de corte é a principal atividade econômica no Pantanal de Mato Grosso. A peculiar posição geográfica e topográfica deste, sendo o elo entre biomas como Amazônia, Cerrado e o Chaco Boliviano e Paraguaio configura um ambiente sujeito ao ritmo do pulso de inundação anual, com períodos úmidos e secos bem marcados que influencia a pecuária desde que estase estabeleceu na região há mais de 200 anos. Apesar desta relação ser conhecida do grande público de longa data, o efeito do regime hidroclimático sobre a produção bovina ainda é pouco descrito e quantificado na literatura. Neste trabalho propomos utilizar a vazão dos principais afluentes do Pantanal de Mato Grosso como indicador das variações hidroclimáticas e verificar como está relacionada com a produção bovina nesta região. Destaca-se que o regime fluviométrico da porção Mato-grossense da Bacia do Alto Paraguai (BAP-MT) é sazonal com estações de seca e chuva bem definidas e vazões variando principalmente no sentido oeste-leste. Já a maior produção bovina ocorre no oeste da BAP-MT nos municípios de Cáceres e Pontes e Lacerda. As duas variáveis são correlatas, podendo inferir que nos momentos mais secos ocorrem maior produção de gado, enquanto em momentos mais úmidos essa produção diminui.
Competitiveness of Smallholder Beef Cattle Farming in Gorontalo District, Gorontalo
Authors: Rouf Ari Abdul , Daryanto Arief , Fariyanti Anna 
Published: October 2019

The objectives of this study were to analyze the competitiveness of the beef cattle farming in Gorontalo District, to analyze the impact of government policies on competitiveness and to analyze the impact of changes in input and output factors of production to competitiveness. Primary data were obtained from 60 respondents were selected using non-probability sampling method. The analysis methods used were Policy Analysis Matrix (PAM) and sensitivity analysis. The results of the analysis showed that the commodity beef cattle in Gorontalo District has a weak competitiveness. The impact of policy to the beef cattle farming showed that the farmers are not protected by government policies (EPC<1). The impact of changes in input and output of production on the competitiveness showed that: 1) the increase in the price of domestic meat and the world respectively 8.44% and 10% will increase the competitiveness, 2) an increase in the price of feeder cattle at 3.28%, forage feed costs by 10% and labor costs by 10% will impact beef cattle farming do not have a competitive advantage but still have a comparative advantage, and 3) increase in meat production about 12.72% will increase the competitiveness of beef cattle.
Fracture of a BIOLOX Delta Ceramic Femoral Head
Authors: Rankin Conor S. , Robinson P. G. , Beattie N. , Gaston P. 
Published: October 2019

Case:
A 52-year-old man underwent right total hip replacement with a 32-mm BIOLOX delta ceramic head with a polyethylene liner. At 8 months, he fell onto his right hip. Radiographs at the time were unremarkable. One month later, he noticed a sharp pain and a sensation of grinding in his right hip; radiographs of the hip showed a fracture of the ceramic head.

Conclusions:
This case further demonstrates that fourth-generation ceramic heads can fracture, and delays in catastrophic failure of ceramics in total hip arthroplasty (THA) following trauma may be secondary to the “slow crack growth” hypothesis.
Severe Leukemoid Reaction in a Case of Soft Tissue Sarcoma
Authors: Xing Zhiqing , Scott Brandon 
Published: October 2019

Case:
A 62-year-old woman presented with severe leukocytosis and systemic symptoms including fatigue, low appetite, and weight loss. After 4 months of evaluation by doctors with extensive laboratory tests and imaging studies, a soft tissue sarcoma in the left posterior distal thigh was revealed. Quickly after surgical excision of the soft tissue sarcoma, the leukocytosis and systemic symptoms were dramatically resolved.

Conclusions:
Leukemoid reaction can present as a paraneoplastic syndrome. Awareness of soft tissue sarcoma as a possible cause of leukemoid reaction may help improve the early diagnosis and subsequent early intervention in future cases.
Nonunion of the Capitate due to Delayed Diagnosis of an Isolated Fracture
Authors: Ochen Yassine , Emmink Benjamin Lucas , Kootstra Thomas Jacobus Martinus , Bosman Willem-Maarten , Wittich Philippe , Keizer Jort 
Published: October 2019

Case:
A 14-year-old girl was diagnosed with nonunion of an isolated capitate fracture 5 months after she first presented to the emergency department. The fracture of the capitate was treated by cancellous proximal bone graft and screw fixation. This current case provides details of the surgical fixation method and long-term functional outcome after nonunion of an isolated capitate fracture after a follow-up of 18 months following fixation.

Conclusions:
Persisting localized tenderness over the capitate should be an indication to perform an additional computed tomography or magnetic resonance imaging scan. Nonunion of isolated capitate fractures can be treated by means of open reduction and internal fixation, with autologous bone grafting.
The nonglacial diamictite of Toutswemogala Hill (lower Karoo Supergroup, central Botswana): Implications on the extent of the late Paleozoic ice age in the Kalahari–Karoo Basin
Authors: Dietrich Pierre , Franchi Fulvio , Setlhabi Larona , Prevec Rose , Bamford Marion 
Published: October 2019

ABSTRACTAlong the easternmost edge of the Karoo–Kalahari Basin (KKB) of Botswana, the Toutswemogala Hill succession exposes a 30–50-m-thick suite of siliciclastic deposits interpreted by some as glaciogenic in origin tied to the Permo-Carboniferous Late Paleozoic Ice Age (LPIA). Six facies associations (FA) were recognized in this succession, resting unconformably on a highly uneven Archean gneissic basement, and consisting from base to top of: 1) clast-supported breccia made up of angular cobbles and boulders ubiquitously derived from the underlying basement, 2) well-bedded siltstones sealing or locally interdigitated with the underlying breccia, and bearing abundant remnants of Glossopteris sp. leaves, 3) a chaotic to faintly laminated matrix-supported diamictite bearing angular and subrounded clasts and tree logs attributed to the genus Megaporoxylon, 4) cross-bedded conglomerate bearing well-rounded quartz and clasts, 5) planar-laminated to ripple-laminated, poorly sorted, muddy sandstones showcasing dispersed mud chips that grade upward into 6) poorly sorted, cross-bedded coarse-grained sandstones displaying convolute beds and abundant imprints of unidentifiable tree logs.No evidence of glaciogenic processes have been found in this succession, in the form of either pavement or clasts striations. The breccia and diamictite are interpreted as scree and mass-flow deposits, respectively. Along with the age of the deposits, inferred from the plant debris (upper Carboniferous to lower Permian), the stratigraphic position of this sedimentary succession resting on the Archean basement suggests that it corresponds to the Dukwi Formation, a stratigraphic equivalent of the Dwyka Group in the Main Karoo Basin. This would explain the resemblance of the facies to those recovered at the base of the central Kalahari–Karoo Basin and in the neighboring Tuli, Ellisras, and Tshipise basins. The absence of diagnostic criteria for glacial processes in the studied succession raises the question of the extent, in both time and space, of the LPIA-related ice masses over southern Africa and particularly in southeastern Botswana. It is suggested here that during this glacial epoch, spatially restricted ice masses were confined in bedrock valleys (valley glaciers) in an uplifted setting otherwise characterized by non-glaciogenic processes, further strengthening the scenario of fragmented ice masses over southern Gondwana.
The stratigraphic evolution of onlap in siliciclastic deep-water systems: Autogenic modulation of allogenic signals
Authors: Soutter Euan L. , Kane Ian A. , Fuhrmann Arne , Cumberpatch Zoë A. , Huuse Mads 
Published: October 2019

ABSTRACTSeafloor topography affects the sediment gravity flows that interact with it. Understanding this interaction is critical for accurate predictions of sediment distribution and paleogeographic or structural reconstructions of deep-water basins. The effects of seafloor topography can be seen from the bed scale, through facies transitions toward intra-basinal slopes, to the basin scale, where onlap patterns reveal the spatial evolution of deep-water systems. Basin-margin onlap patterns are typically attributed to allogenic factors, such as sediment supply signals or subsidence rates, with few studies emphasizing the importance of predictable spatio-temporal autogenic flow evolution. This study aims to assess the autogenic controls on onlap by documenting onlap styles in the confined Eocene-to-Oligocene deep-marine Annot Basin of SE France. Measured sections, coupled with architectural observations, mapping, and paleogeographical interpretations, are used to categorize onlap styles and place them within a generic stratigraphic model. These observations are compared with a simple numerical model. The integrated stratigraphic model predicts that during progradation of a deep-water system into a confined basin successive onlap terminations will be partially controlled by the effect of increasing flow concentration. Initially thin-bedded low-density turbidites of the distal lobe fringe are deposited and drape basinal topography. As the system progrades these beds become overlain by hybrid beds and other deposits of higher-concentration flows developed in the proximal lobe fringe. This transition is therefore marked by intra-formational onlap against the underlying and lower-concentration lobe fringe that drapes the topography. Continued progradation results in deposition of lower-concentration deposits in the lobe off-axis, resulting in either further intra-formational onlap against the lobe fringe or onlap directly against the hemipelagic basin margin. Basinal relief is gradually reduced as axial and higher-volume flows become more prevalent during progradation, causing the basin to become a bypass zone for sediment routed down-dip. This study presents an autogenic mechanism for generating complex onlap trends without the need to invoke allogenic processes. This has implications for sequence-stratigraphic interpretations, basin subsidence history, and forward modeling of confined deep-water basins.