bluuebunny/crossref_metadata_2025_split huggingface dataset:
The ambience of collaboration in coworking environments
Authors: Orel Marko , Alonso Almeida María del Mar 
Published: July 2019

Purpose
The purpose of this paper is to take an explanatory role and analyse the development of workspace ambiences in coworking spaces which optimise the chance of interactivity between individual users and leading towards cooperation. The paper thus offers a discussion on how the ambience that is tailored to a particular coworking space enhances the possibility of collaboration between two or more users of a selected workspace.

Design/methodology/approach
Ethnographically guided observations of six coworking spaces and qualitative interviews with their managers were used to gain an understanding of the workspace ambiences in coworking spaces. As direct measurement of the frequency of collaboration would be logistically profound, this paper rather explores the conditions for spontaneous or moderated interactivity between workspace users, which may be regulated by the creation of an optimal coworking space ambience.

Findings
The following paper defines the coworking space ambience as the look and the feel of a work environment which can arouse certain moods towards a particular place and its users. Coworking spaces may impose various approaches that not only attract potential workspace users and form initial ties between them but also produce a certain ambience that leads to collaborative action between users. The factors of spatial design need to be adapted, and engagement strategies need to be constructed to maximise the preferential output. The research behind the following paper concludes that the factors of spatial comfortability are an essential predisposition for workspace users to engage in cooperation with each other. Various mechanisms are needed to customise these engagements into cooperative action.

Originality/value
While the outcomes of sharing these environments have been periodically explored, no attempts have been made to investigate how coworking ambience is being created and implemented to optimise collaborative efforts of individuals who are sharing the workspace. For that reason, the audience of this paper should not only be limited to academics but may also be suitable for managers and office-space operators seeking to understand dynamics of collaboration within new types of shared office spaces.
Quantifying the potential impact of a green supporting factor or brown penalty on European banks and lending
Authors: Thomä Jakob , Gibhardt Kyra 
Published: July 2019

Purpose
The European Parliament and Commission are considering introducing a green supporting factor (GSF) or brown penalty (BP) for capital reserve requirements. This paper aims to estimate the potential impact such a policy intervention may have on both capital reserves of European banks and the cost and availability of capital to “green” and “brown” investments.

Design/methodology/approach
The paper draws on the existing empirical and theoretical literature on the impacts of changes to capital reserve requirements on the real economy. It applies these estimates on the particular policy intervention currently being discussed at EU level to estimate the potential range of impacts on the cost of capital – measured in basis points – and the availability of capital – measured in per cent changes to lending.

Findings
A GSF would have a limited effect on overall capital requirements of banks compared to a BP – given the larger universe of assets on which such a penalty would be applied. The estimated effect is a reduction in capital requirements associated with a GSF of around €3-4bn based on baseline “green” definitions. In terms of cost of capital, the paper estimates a reduction of 5 to 26 basis points for green projects (with inverse expected effects for a BP). In terms of availability of capital, analysing a BP suggests a potential reduction in lending to brown assets of up to 8 per cent.

Originality/value
The paper provides direct evidence, with the first quantitative analysis of the potential impact of the current policy proposition discussed at EU-level.
Exchange variables, organizational culture and their relationship with constructive deviance
Authors: Cohen Aaron , Ehrlich Sari 
Published: July 2019

Purpose
Constructive deviance is a behavior that can contribute to the effectiveness of an organization despite its problematic nature. Too few studies have examined the correlates of this behavior. The purpose of this study is to examine variables that represent exchange and organizational culture and their relationship to supervisor-reported and self-reported constructive deviance.

Design/methodology/approach
The survey data were collected from 602 employees (a response rate of 67 per cent) in a large municipality in central Israel. Hierarchical linear modeling (HLM) analyses were performed for each of the dependent variables (three self-reported constructive deviances and three supervisor-reported constructive deviance) controlling for divisions and departments.

Findings
The findings showed that self-reported constructive deviance was explained much better by the independent variables than supervisor-reported deviance. Organizational justice and moral identity had a strong direct effect on constructive deviance (self-reported). The mediation effect showed that an organizational climate for innovation had the strongest mediation effect among the mediators. Psychological contract breach was found to have a limited effect on constructive deviance.

Practical implications
Organizations should encourage procedural justice to encourage their employees to act in support of the organization, whether openly (formal performance) or more secretly (constructive deviance). Also, organizations should support innovation climate if they want to increase constructive deviance of their employees.

Originality/value
In a time when innovation and creativity are gaining increasing importance as behaviors that contribute to organizational success, more research on constructive deviance is expected. This study increases our understanding of this important concept stimulates additional studies of it.
New university, new possibilities: higher education in Western Canada
Authors: Atkinson David W. 
Published: July 2019

Purpose
This paper aims to examine the new teaching universities created in British Columbia and Alberta over the past 10 years in the context of the multiple challenges faced by higher education today, including issues of purpose, culture, governance, accountability and finances.

Design/methodology/approach
The essay provides a historic overview of the challenges universities face today. In this context, it presents the new Western Canadian universities as a possible model, even while identifying the challenges these institutions face in the future.

Findings
This case study concludes that universities must change if they are to meet the expectations of students and the needs of society. It outlines the challenges faced by the new universities, how they have responded, the successes they have experienced and the challenges they confront.

Originality/value
To the best of the author’s knowledge, this is the first study of the new Canadian universities.
8‐Methoxypsoralen protects bovine mammary epithelial cells against lipopolysaccharide‐induced inflammatory injury via suppressing JAK/STAT and NF‐κB pathway
Authors: Li Jiandong , Yin Peng , Gong Ping , Lv An , Zhang Zhicong , Liu Fenghua 
Published: July 2019

AbstractBovine mastitis is the most common disease in dairy cattle. Bacterial infections are the main cause of mastitis. Lipopolysaccharide (LPS), a major structural component of the cell wall of Escherichia coli, is a good inducer used to replicate inflammation models. 8‐Methoxypsoralen (8‐MOP), a formerly considered photosensitizing agent, has been used in immunotherapy. This study investigated the protective effects of 8‐MOP on LPS‐induced inflammatory injury in bovine mammary epithelial cells (BMECs). LPS treatment (50 μg/mL for 12 hr) caused a decrease in cell viability, morphological damage, and cell apoptosis. Pretreatment with 8‐MOP at concentrations of 25 and 50 μg/ml significantly attenuated LPS‐induced inflammation in BMECs. qRT‐PCR analysis revealed that the messenger RNA expression of inflammatory cytokines and chemokine (interleukin‐1β [IL‐1β], IL‐6, tumor necrosis factor‐α, and IL‐8) was suppressed by 8‐MOP in LPS‐stimulated BMECs. Western blot analysis showed that 8‐MOP could also reduce the protein levels of cyclooxygenase‐2 and promote the translocation of high‐mobility group box 1 from the nucleus to cytoplasm. Furthermore, the anti‐inflammatory property of 8‐MOP was mediated by inhibiting nuclear factor kappa‐light‐chain‐enhancer of activated B cells activation and STAT1 phosphorylation. Taken together, 8‐MOP could protect cells from inflammatory injury induced by LPS, and may be a potential agent against bovine mastitis.
Geological gas‐storage shapes deep life
Authors: Ranchou‐Peyruse Magali , Auguet Jean‐Christophe , Mazière Camille , Restrepo‐Ortiz Claudia Ximena , Guignard Marion , Dequidt David , Chiquet Pierre , Cézac Pierre , Ranchou‐Peyruse Anthony 
Published: July 2019

SummaryAround the world, several dozen deep sedimentary aquifers are being used for storage of natural gas. Ad hoc studies of the microbial ecology of some of them have suggested that sulfate reducing and methanogenic microorganisms play a key role in how these aquifers' communities function. Here, we investigate the influence of gas storage on these two metabolic groups by using high‐throughput sequencing and show the importance of sulfate‐reducing Desulfotomaculum and a new monophyletic methanogenic group. Aquifer microbial diversity was significantly related to the geological level. The distance to the stored natural gas affects the ratio of sulfate‐reducing Firmicutes to deltaproteobacteria. In only one aquifer, the methanogenic archaea dominate the sulfate‐reducers. This aquifer was used to store town gas (containing at least 50% H2) around 50 years ago. The observed decrease of sulfates in this aquifer could be related to stimulation of subsurface sulfate‐reducers. These results suggest that the composition of the microbial communities is impacted by decades old transient gas storage activity. The tremendous stability of these gas‐impacted deep subsurface microbial ecosystems suggests that in situ biotic methanation projects in geological reservoirs may be sustainable over time.
Descriptive Analysis and Consumer Acceptability of Locally and Commercially Grown Spinach
Authors: Batziakas Konstantinos G. , Talavera Martin , Swaney‐Stueve Marianne , Rivard Cary L. , Pliakoni Eleni D. 
Published: July 2019

AbstractThe consumer demand for locally grown fresh produce is continuously increasing in the United States. The high tunnel systems have been successfully utilized by small acreage growers for local production. Consumers are typically assessing appearance, freshness, flavor and aroma when purchasing produce. A common perception is that locally grown produce tastes better than nonlocal. However, there is not much evidence for supporting this claim. The objective of this study was to identify consumer acceptability and the sensory characteristics/differences of locally grown spinach in open field or in high tunnel and nonlocal commercially grown spinach. Spinach, Spinacia oleracea cv. “Corvair” was grown in open field and in high tunnel at Kansas State Univ. Olathe Horticulture Research and Extension Center (OHREC) in spring 2017 and the commercially grown spinach was purchased at a local retail store. A consumer study (n = 205) was conducted at Kansas State Univ., Olathe campus, and a descriptive sensory analysis was conducted by a highly trained descriptive analysis panel in the Center for Sensory Analysis and Consumer Behavior at Kansas State Univ., Manhattan campus, in spring 2017. The consumer test showed that high tunnel spinach scored significantly higher in overall liking (P < 0.0001), flavor liking (P < 0.0001), and texture liking (P < 0.05) when compared to open field and store purchased spinach. Descriptive analysis showed that locally grown spinach had higher intensity of attributes that indicate premium quality, such as green color and green/spinach flavors. Our results indicate that locally grown spinach was preferred from the consumers for its high organoleptic quality.Practical ApplicationLocally grown spinach demonstrated high intensity in a set of sensory attributes that suggest a product with premium organoleptic quality. Correspondingly to these results, consumers liked spinach produced locally in high tunnels the most. The results of this study can be used for developing marketing strategies that are aiming specifically to the consumer niche that is seeking fresh produce of high organoleptic quality.
Combined Osmotic and Membrane Distillation for Concentration of Anthocyanin from Muscadine Pomace
Authors: Anari Zahra , Mai Chuqiao , Sengupta Arijit , Howard Luke , Brownmiller Cindi , Wickramasinghe S. Ranil 
Published: July 2019

AbstractBioactive anthocyanins from aqueous extracts of muscadine grape pomace were concentrated using osmotic distillation (OD) and direct contact membrane distillation (DCMD) using polypropylene (PP) and poly(ethylene chlorotrifluoroethylene) (ECTFE) membranes. The driving force for OD is created by using a high concentration brine solution while the driving force for DCMD is generated by elevating the feed temperature relative to the permeate temperature. The brine concentration used was 4 M. The lowest fluxes were obtained for OD. Given the temperature sensitive nature of anthocyanins, the maximum temperature difference during DCMD was limited to 30 °C. The feed temperature was 40 °C and the permeate at 10 °C. Consequently, the maximum flux during DCMD was also limited. A combination of OD and DCMD was found to give the highest fluxes. High‐performance liquid chromatography (HPLC) and HPLC‐electrospray mass spectrometry were used to identify and quantify anthocyanins, cyanidin‐3,5‐O‐diglucoside, delphinidin‐3,5‐O‐diglucoside, petunidin‐3,5‐O‐diglucoside, peonidin‐3,5‐O‐diglucoside, and malvidin‐3,5‐O‐diglucoside. The results obtained here suggest that, though water fluxes for DI water feed streams for PP and ECTFE membrane were similar, the fluxes obtained for the two membranes when using muscadine pomace extracts were different. Concentration factors of close to 3 was obtained for anthocyanins. Membranes also showed slightly different performance in the concentration process. Membrane surfaces were analyzed using scanning electron microscopy and Fourier‐transformed infrared spectroscopy. The results suggest that adsorption of these anthocyanins on the membrane surface lead to performance differences. In an actual operation, selection of an appropriate membrane and regeneration of the membrane will be important for optimized performance.Practical ApplicationsAnthocyanins are valuable therapeutic compounds, which are found in the solid residue left following fruit juice pressing. However, recovery and concentration of these therapeutic compounds remains challenging due to their stability. Here, a novel membrane‐based unit operation has been investigated in order to concentrate the anthocyanins that have been extracted into aqueous solutions. The unit operation investigated here use mild processing conditions. Insights into the factors that need to be considered when optimizing of the unit operation for commercialization are discussed.
Changes Over the Fermentation Period in Phenolic Compounds and Antioxidant and Anticancer Activities of Blueberries Fermented by Lactobacillus plantarum
Authors: Ryu Ji‐Yeon , Kang Hye Rim , Cho Somi Kim 
Published: July 2019

AbstractThis study determined the effects of blueberry fermentation by Lactobacillus plantarum on antioxidant and anticancer activities. The fermented blueberries extracted with 80% ethanol (FBE) showed increased superoxide dismutase‐like activity, increased scavenging of DPPH and alkyl radicals, and increased antiproliferative activity against human cervical carcinoma HeLa cells by inducing apoptosis. Seven representative phenolic compounds (malvidin 3‐O‐glucopyranoside, gallic acid, protocatechuic acid, catechol, chlorogenic acid, syringic acid, and epigallocatechin) in FBE were measured by high‐performance liquid chromatography at different fermentation times. The content of each phenolic compound in the FBE was dependent on the fermentation period. Protocatechuic acid and catechol levels increased significantly with fermentation time. Of these three major compounds (protocatechuic acid, catechol, and chlorogenic acid), catechol showed the most significant anticancer activity when HeLa cells were treated with each of these three compounds alone or mixed in various ratios. Pearson's product‐moment correlation analysis revealed that the increases in antioxidant and anticancer activities following blueberry fermentation were positively correlated with the phenolic acids present in FBE.Practical ApplicationBlueberries fermented with a tannase‐producing lactic acid bacteria (LAB), Lactobacillus plantarum showed higher antioxidant activities and antiproliferative activities against human cervical carcinoma HeLa cells than did raw blueberries. L. plantarum fermentation biotransformed blueberry polyphenols into active phenol metabolites with strong antioxidant and antiproliferative activities. Our results suggest that fermented blueberries are rich in phenolic acids, which are a promising source of natural antioxidants and anticancer drugs and can be used as additives in food, pharmaceuticals, and cosmetic preparations.
Analysis of central venous access injuries from claims to the Swedish Patient Insurance Company 2009‐2017
Authors: Lindgren Sophie , Gustafson Pelle , Hammarskjöld Fredrik 
Published: July 2019

IntroductionInsertion and use of central venous access devices (CVADs) can be associated with serious adverse events. The incidence is generally low but considering the vast use of CVADs the consequences can, from a patient safety and health economics perspective, be severe. No exact knowledge exists of number of catheters or complications in Sweden, as there is currently no comprehensive registry. The aim was to analyse injuries reported to the Swedish National Patient Insurance Company (Löf) within 7 days after insertion or removal of a CVAD.MethodsA retrospective analysis of all injuries filed in the period 2009‐2017 was performed, evaluating patient data, type of catheter, insertion technique and type of injury. If the injury was deemed avoidable by Löf, degree of disability and mortality was registered.ResultsA total of 87 claims of injuries were found of which 36 (41%) were assessed as avoidable.The most common injuries were: bleeding (18%), early infection (17%), pneumothorax (17%) and early thrombosis (15%). No patients died of their injuries, but 17 of 36 suffered permanent disability of varying degrees. Ultrasound‐guided insertion was used in 19% of the cases.ConclusionIn Sweden, few injuries related to CVAD use are reported to Löf. About 40% of filed claims were categorized as having an avoidable injury and therefore eligible for compensation. About half of the compensated patients suffered a permanent disability. The results indicate underreporting of CVC‐related injuries in Sweden during the studied time‐period.
Hsp90β interacts with MDM2 to suppress p53‐dependent senescence during skeletal muscle regeneration
Authors: He Min Yi , Xu Shui Bo , Qu Zi Hao , Guo Yue Mei , Liu Xiao Ceng , Cong Xiao Xia , Wang Jian Feng , Low Boon Chuan , Li Li , Wu Qiang , Lin Peng , Yan Shi Gui , Bao Zhang , Zhou Yi Ting , Zheng Li Ling 
Published: July 2019

AbstractCellular senescence plays both beneficial and detrimental roles in embryonic development and tissue regeneration, while the underlying mechanism remains elusive. Recent studies disclosed the emerging roles of heat‐shock proteins in regulating muscle regeneration and homeostasis. Here, we found that Hsp90β, but not Hsp90α isoform, was significantly upregulated during muscle regeneration. RNA‐seq analysis disclosed a transcriptional elevation of p21 in Hsp90β‐depleted myoblasts, which is due to the upregulation of p53. Moreover, knockdown of Hsp90β in myoblasts resulted in p53‐dependent cellular senescence. In contrast to the notion that Hsp90 interacts with and protects mutant p53 in cancer, Hsp90β preferentially bound to wild‐type p53 and modulated its degradation via a proteasome‐dependent manner. Moreover, Hsp90β interacted with MDM2, the chief E3 ligase of p53, to regulate the stability of p53. In line with these in vitro studies, the expression level of p53‐p21 axis was negatively correlated with Hsp90β in aged mice muscle. Consistently, administration of 17‐AAG, a Hsp90 inhibitor under clinical trial, impaired muscle regeneration by enhancing injury‐induced senescence in vivo. Taken together, our finding revealed a previously unappreciated role of Hsp90β in regulating p53 stability to suppress senescence both in vitro and in vivo.
The patient co‐payment and opportunity costs of accessing healthcare for Indigenous Australians with cancer: A whole of population data linkage study
Authors: Callander Emily , Bates Nicole , Lindsay Daniel , Larkins Sarah , Preston Robyn , Topp Stephanie M. , Cunningham Joan , Garvey Gail 
Published: July 2019

AbstractAimTo quantify the direct out‐of‐pocket patient co‐payments and time opportunity costs (length of hospital stay) incurred by Indigenous and non‐Indigenous persons diagnosed with cancer during the first year postdiagnosis.MethodsCancerCostMod was used, which is a model of cancer costs based upon a whole‐of‐population data linkage. The base population was a census of all persons diagnosed with cancer in Queensland, Australia between 1 July 2011 and 30 June 2012 (n = 25,553). Individual records were linked to corresponding Queensland Health Admitted Patient Data Collection, Emergency Data Information System, Medicare Benefits Schedule, and Pharmaceutical Benefits Scheme records between 1 July 2011 and 30 June 2015. Queensland data were weighted to be representative of the Australian population (approximately 123,900 Australians, 1.7% Indigenous Australians).ResultsAfter adjusting for age, sex, rurality, area‐based deprivation, and cancer group, Indigenous Australians accrued significantly less in postdiagnosis patient co‐payments at 0–6 months (61% less) and 7–12 months (63% less). Indigenous Australians also had significantly fewer postdiagnosis hospitalizations at 0–6 months (21% fewer) and 7–12 months (27% fewer).ConclusionThere is growing concern regarding the financial burden of cancer to the patient. The time spent away from family and their community may also have an important time opportunity cost, which may affect a person's decision to undertake or continue treatment. This is the first study in Australia to identify the financial cost of co‐payments for Indigenous people with cancer, as well as the number and length of hospitalizations as drivers of time opportunity costs.