bluuebunny/crossref_metadata_2025_split huggingface dataset:
Super Obesity in the Medical Intensive Care Unit
Authors: Kumar Santhi Iyer , Doo Kathleen , Sottilo-Brammeier Julie , Lane Christianne , Liebler Janice M. 
Published: March 2018

Background: Studies exploring the effect of body mass index (BMI) on outcomes in the intensive care unit (ICU) have yielded mixed results, with few studies assessing patients at the extremes of obesity. We sought to understand the clinical characteristics and outcomes of patients with super obesity (BMI > 50 kg/m2) as compared to morbid obesity (BMI > 40 kg/m2) and obesity (BMI > 30 kg/m2). Methods: A retrospective review of patients admitted to the Los Angeles County + University of Southern California medical intensive care unit (MICU) service between 2008 and 2013 was performed. The first 150 patients with BMI 30 to 40, 40 to 50, and 50+ were separated into groups. Demographic data, comorbid conditions, reason for admission, Acute Physiology and Chronic Health Evaluation II (APACHE II) scores, serum bicarbonate, and arterial carbon dioxide pressure (Pco 2) at admission were collected. Hospital and ICU length of stay (LOS), discharge disposition, mortality, use of mechanical ventilation (invasive and noninvasive), use of radiography, and other clinical outcomes were also recorded. Results: There was no difference in age, sex, and APACHE II score among the 3 groups. A pulmonary etiology was the most common reason for admission in the higher BMI categories ( P < .001). There was no difference in mortality among the groups. Intensive care unit and hospital LOS rose with increasing BMI ( P < .001). Patients admitted for pulmonary etiologies and higher BMIs had an increased ICU and hospital LOS ( P < .001). Super obese patients used significantly more noninvasive mechanical ventilation (NIMV, P < .001). There were no differences in the use of invasive mechanical ventilation across the groups. Conclusion: Super obese patients are most commonly admitted to the MICU with pulmonary diagnoses and have an increased use of noninvasive ventilation. Super obesity was not associated with increased ICU mortality. Clinicians should be prepared to offer NIMV to super obese patients and anticipate a longer LOS in this group.
Comparing surgically induced astigmatism calculated by means of simulated keratometry versus total corneal refractive power
Authors: Garzón Nuria , Rodríguez-Vallejo Manuel , Carmona David , Calvo-Sanz Jorge A , Poyales Francisco , Palomino Carlos , Zato-Gómez de Liaño Miguel Á , Fernández Joaquín 
Published: March 2018

Purpose: To evaluate surgically induced astigmatism as computed by means of either simulated keratometry (KSIM) or total corneal refractive power (TCRP) after temporal incisions. Methods: Prospective observational study including 36 right eyes undergoing cataract surgery. Astigmatism was measured preoperatively during the 3-month follow-up period using Pentacam. Surgically induced astigmatism was computed considering anterior corneal surface astigmatism at 3 mm with KSIM and considering both corneal surfaces with TCRP from 1 to 8 mm (TCRP3 for 3 mm). The eyes under study were divided into two balanced groups: LOW with KSIM astigmatism <0.90 D and HIGH with KSIM astigmatism ≥0.90 D. Resulting surgically induced astigmatism values were compared across groups and measuring techniques by means of flattening, steepening, and torque analysis. Results: Mean surgically induced astigmatism was higher in the HIGH group (0.31 D @ 102°) than in the LOW group (0.04 D @ 16°). The temporal incision resulted in a steepening in the HIGH group of 0.15 D @ 90°, as estimated with KSIM, versus 0.28 D @ 90° with TCRP3, but no significant differences were found for the steepening in the LOW group or for the torque in either group. Differences between KSIM- and TCRP3-based surgically induced astigmatism values were negligible in LOW group. Conclusion: Surgically induced astigmatism was considerably higher in the high-astigmatism group and its value was underestimated with the KSIM approach. Eyes having low astigmatism should not be included for computing the surgically induced astigmatism because steepening would be underestimated.
Operative Trends in the Treatment of Hip Fractures and the Role of Arthroplasty
Authors: Grau Luis , Summers Spencer , Massel Dustin H. , Rosas Samuel , Ong Alvin , Hernandez Victor Hugo 
Published: March 2018

Introduction: There is a projected exponential increase in the number of hip fractures in the United States. Trends in patient demographics and the role of total hip arthroplasty (THA) and its associated outcomes following hip fractures surgery have not been well studied. Methods: Patients with proximal femur fractures between 1990 and 2007 were identified in the National Hospital Discharge Survey database. Demographics, comorbidities, perioperative complications, and discharge status for patients undergoing THA, hemiarthroplasty, or internal fixation were examined. Multivariable regression was performed to determine independent risk factors for perioperative complications. Results: Between 1990 and 2007, there was a statistically significant increase in patient age, adverse events, medical comorbidities, surgical complications, medical complications, and nonroutine discharge across all surgical treatment modalities. In the same time period, the utilization of THA for all fracture types decreased significantly. Discussion: Total hip arthroplasty was found to be an independent risk factor for perioperative complications. Orthopedic surgeons should be aware that the hip fracture population continues to get older, with more medical comorbidities and are at higher risk for perioperative complications. Conclusion: Total hip arthroplasty is associated with a higher rate of perioperative complications in the hip fracture population.
Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
Authors: Cortes Jorge E. , Kim Dong-Wook , Pinilla-Ibarz Javier , le Coutre Philipp D. , Paquette Ronald , Chuah Charles , Nicolini Franck E. , Apperley Jane F. , Khoury H. Jean , Talpaz Moshe , DeAngelo Daniel J. , Abruzzese Elisabetta , Rea Delphine , Baccarani Michele , Müller Martin C. , Gambacorti-Passerini Carlo , Lustgarten Stephanie , Rivera Victor M. , Haluska Frank G. , Guilhot François , Deininger Michael W. , Hochhaus Andreas , Hughes Timothy P. , Shah Neil P. , Kantarjian Hagop M. 
Published: March 2018

Key Points
Ponatinib continued to provide deep, durable responses in heavily pretreated patients with CP-CML. Tolerability was acceptable in this heavily pretreated population with 5 years of follow-up.
Investigating the effectiveness of the Trigonella foenum-graecum L. (fenugreek) seeds in mild asthma: a randomized controlled trial
Authors: Emtiazy Majid , Oveidzadeh Laleh , Habibi Minoo , Molaeipour Leila , Talei Daryush , jafari Zahra , Parvin Mahmoud , Kamalinejad Mohammad 
Published: March 2018

Abstract
Background
Asthma is one of the important chronic diseases. The asthma prevalence is increasing in last decades. Despite the presence of good controller drugs like corticosteroids, about 60% of asthmatic patients use alternative medicine. This study was done to determine the effectiveness of Tregonella foenum graceum (fenugreek) seeds in mild asthma.

Methods
It is a double blind trial with placebo effect. One of the ancient prescriptions from Persian Medicine was selected. The participants were divided to three groups randomly. On group received fenugreek syrup one received honey syrup and the third received placebo. Duration of treatment was 4 weeks. Quality of life, Lung function tests and IL-4 levels were evaluated before and after treatment.

Results
From 90 participants to study 79 completed the process. After study there was significant increase in quality of the life and lung function tests and IL-4 levels in fenugreek and honey groups.

Conclusion
FEV1 level was improved more than 10% in fenugreek group. Treatment was well tolerated. No serious side effects were reported during the study. The aqueous extract of fenugreek seeds appears to be effective and safe in treatment of mild asthma.
Trial registration The study was recorded with the Iranian Registry of Clinical trials [http://www.irci.ir], registration code: IRCT2016011325991N1
Gas hydrate quantification using full-waveform inversion of sparse ocean-bottom seismic data: A case study from Green Canyon Block 955, Gulf of Mexico
Authors: Wang Jiliang , Jaiswal Priyank , Haines Seth S. , Hart Patrick E. , Wu Shiguo 
Published: March 2018

We present a case study of gas hydrate quantification using dense short-offset multichannel seismic (MCS) and sparse long-offset ocean-bottom-seismometer (OBS) data in lease block Green Canyon 955 (GC955), Gulf of Mexico (GOM), where the presence of gas hydrate was interpreted using logging while drilling (LWD) data acquired by the GOM Gas Hydrate Joint Industry Project Leg II expedition. We use frequency-domain full-waveform inversion (FWI) of seven OBS gathers to invert for a P-wave velocity model of an approximately 7 km long MCS profile connecting two LWD sites, GC955-H and GC955-Q. We build the starting model for FWI using traveltime inversion (TI) of the MCS and OBS data. In addition, we use the TI model for depth migrating the MCS stack. At the LWD sites, we constrain the hydrate saturation ([Formula: see text]) using sonic and resistivity logs. Unfortunately, as is typical of seismic quantification problems, the FWI model resolution is not sufficient to extrapolate the LWD-based [Formula: see text]. Therefore, we apply Backus averaging to the sonic log, at 60 m wavelength, bringing it within approximately 8% of the FWI model and make the assumption that averaging the sonic log is same as redistributing the gas hydrate within the Backus wavelength. In this manner, instead of [Formula: see text], the FWI model is able to estimate the total gas hydrate volume. In the end, we use the FWI model and the migrated stack to constrain the locations and bulk volumes of free gas and gas hydrate. Our results demonstrate that with careful processing, reasonable estimates on locations and bulk volumes of submarine gas hydrate accumulations can be achieved even with sparse seismic data that are not adequate for amplitude-based assessments.
A radiogenomic analysis of hepatocellular carcinoma: association between fractional allelic imbalance rate index and the liver imaging reporting and data system (LI-RADS) categories and features
Authors: Furlan Alessandro , Almusa Omar , Yu Robinson K , Sagreiya Hersh , Borhani Amir A , Bae Kyongtae T , Marsh J Wallis 
Published: March 2018

Objective:
To evaluate the association between the liver imaging reporting and data system (LI-RADS) categories and features and the fractional allelic imbalance (FAI) rate index of hepatocellular carcinoma (HCC).

Methods:
The institutional review board approved this retrospective study. Medical records collected between January 2008 and December 2013 were reviewed to find patients with histologically confirmed HCC, FAI analysis, and CT or MR imaging of the liver. The final population included 71 patients (54 males, 17 females). Three radiologists reviewed the images using the LI-RADS v. 2014. The association between FAI and LI-RADS categories and features was tested using the Spearman’s rank correlation coefficient (rho) and the Wilcoxon rank-sum test [low FAI (&lt;40%) v s high FAI (≥40%)]. A p value &lt; 0.007 was used as the threshold for statistical significance after application of the Bonferroni correction for multiple comparisons.

Results:
HCCs were classified as LR-3 (n = 4), LR-4 (n = 22), and LR-5 (n = 45). There was a positive correlation (rho = 0.264) between FAI rate index and LI-RADS category, although not statistically significant after Bonferroni correction (p = 0.024). 14 of the 20 (70%) HCCs with high FAI (≥40%) were categorized as LR-5, 6/20 (30%) as LR-4 and none as LR-3 (p = 0.377). Among the evaluated LI-RADS imaging features, only lesion size showed a statistically significant different distribution in tumors with high FAI compared to those with low FAI. HCCs with FAI ≥40% were larger (56 ± 42 mm) compared to those with FAI &lt;40% (36 ± 30 mm; p = 0.005).

Conclusion:
There was a positive correlation, although not statistically significant, between the LI-RADS diagnostic categories and the FAI rate of HCC. Tumors with high FAI were larger compared to those with low FAI.

Advances in knowledge:
HCCs with high (≥40%) FAI are larger compared to those with low (&lt;40%) FAI.
Świat bez kultury
Authors: Gurczyńska-Sady Katarzyna 
Published: March 2018

A World without Culture. Considerations on the Consequences of the Eugenic Revolution
The intention of eugenicists has always been an attempt to repair the state of society by improving the quality of the so‑called human material. These special social reforms lead from the correction of man – conducted by means of cultivation – to the correction of the world in which he lives and develops. Eugenicists believe that if we take care of the quality of the human body, at the same time, we will take care of the quality of our social life. This article discredits this argument by showing the scarcity of the anthropology hidden in theoretical declarations of eugenicists and the naivety of the allegations about the mechanism of the development of culture. The thesis which says that a new better man creates a new and better world is shown to be as an empty dogma. In place of the standard questions about whether the world without “misfits” would be a better world the article asks the question: How would the designed luxury of total security and prosperity influence people? The answer shows that a community after the eugenic revolution is not what we call a society. The conditions of human development under eugenic treatment are not the conditions of the development of culture.
Dracula unseen: The death and afterlife of Hammer’s Vlad the Impaler
Authors: Foster Kieran 
Published: March 2018

Abstract
Few production companies have been as synonymous with one genre as Hammer Films and its horror output. However, for every ‘Hammer Horror’ successfully produced, several potential projects failed to make it into production. This article will utilize five separate drafts of the unmade Hammer project Vlad the Impaler, an adaptation of a BBC Radio 4 Drama produced in 1974. Utilizing Vlad the Impaler as a case study will allow for a further contextualization of Hammer’s production methods between 1975 and 1979, a period in which Hammer only produced two theatrical films. The project was also developed further throughout the 1980s/1990s, at a time when Hammer did not produce a single film. More broadly, this article will use Vlad the Impaler as a methodological case study, and examine how we can expand on existing works within the field on unmade adaptations.
The old monster in the new world: The Americanization of the vampire
Authors: Kandyli Aspa , Zontos Michail 
Published: March 2018

Abstract
This article sets out to explore how the vampire, a quintessential European monster which has been related to aristocracy, blood purity and colonialism, has been radically transformed following its migration to America. By adapting to the conditions of the New World, the creature has been Americanized by gradually abandoning its European traits – a process similar to the one described by exponents of Americanization such as Frederick Jackson Turner. During this transformation, the creature that once was a destructive force of nature has essentially been humanized. Instead of an animated corpse that lurks in the shadows, the vampire becomes a historian and an agent of history, occasionally a positive one. In this re-imagination of the American vampire we can discern ideas of American exceptionalism. At the same time, this transformation allows the vampire to become a vocal critic of the negative aspects of American history. The article explores the Americanization of the vampire by underlining the balance between the concepts of the vampire as an agent of American superiority and as a reliable narrator of the country’s history as expressed in seminal works of American vampire fiction.
Special cubic Cremona transformations of ℙ6and ℙ7
Authors: Staglianò Giovanni 
Published: March 2018

AbstractA famous result of Crauder and Katz (1989) concerns the classification of special Cremona transformations whose base locus has dimension at most two. They also proved that a special Cremona transformation with base locus of dimension three has to be one of the following: 1) a quinto-quintic transformation of ℙ5; 2) a cubo-quintic transformation of ℙ6; or 3) a quadro-quintic transformation of ℙ8. Special Cremona transformations as in Case 1) have been classified by Ein and Shepherd-Barron (1989), while in our previous work (2013), we classified special quadro-quintic Cremona transformations of ℙ8. Here we consider the problem of classifying special cubo-quintic Cremona transformations of ℙ6, concluding the classification of special Cremona transformations whose base locus has dimension three.
Forms, Dialectics and the Healthy Community: The British Idealists’ Receptions of Plato
Authors: Tyler Colin 
Published: March 2018

Abstract:
This article counters the dominant misinterpretations of the British idealists’ readings of Plato, thereby fundamentally undermining the current historiography of Plato’s modern reception in the English-speaking world. Section one introduces the topic, before section two explores the British idealists’ celebration of Plato. Section three argues against the fundamental assumption of the current historiography: that the British idealists were dogmatic Neo-Platonic Hegelians. Rather, while the British idealists recognised Plato’s sometimes dogmatic formulations of the forms, they saw greater philosophical value in his “searching” texts. They appreciated the provisional, inchoate character of human conceptualisations of the forms and emphasised our responsibility to test them. Section four highlights the British idealists’ recognition of Plato’s literary turn. Section five demonstrates that, contrary to the received view of Plato scholars, the British idealists themselves were egalitarians who prioritised personal virtue, decentralised debate and local self-determination. I conclude that the British idealists interpreted Plato in ways that differed significantly from Jowett and the current historiography.
Design and manufacture of super-multilayer optical filters based on PARMS technology
Authors: Lü Shaobo , Wang Ruisheng , Ma Jing , Jiang Chao , Mu Jiali , Zhao Shuaifeng , Yin Xiaojun 
Published: March 2018

Abstract
Three multilayer interference optical filters, including a UV band-pass, a VIS dual-band-pass and a notch filter, were designed by using Ta2O5, Nb2O5, Al2O3 and SiO2 as high- and low-index materials. During the design of the coating process, a hybrid optical monitoring and RATE-controlled layer thickness control scheme was adopted. The coating process was simulated by using the optical monitoring system (OMS) Simulator, and the simulation result indicated that the layer thickness can be controlled within an error of less than ±0.1%. The three filters were manufactured on a plasma-assisted reactive magnetic sputtering (PARMS) coating machine. The measurements indicate that for the UV band-pass filter, the peak transmittance is higher than 95% and the blocking density is better than OD6 in the 300–1100 nm region, whereas for the dual-band-pass filter, the center wavelength positioning accuracy of the two passbands are less than ±2 nm, the peak transmittance is higher than 95% and blocking density is better than OD6 in the 300–950 nm region. Finally, for the notch filter, the minimum transmittance rates are >90% and >94% in the visible and near infrared, respectively, and the blocking density is better than OD5.5 at 808 nm.
Simulation of the optical coating deposition
Authors: Grigoriev Fedor , Sulimov Vladimir , Tikhonravov Alexander 
Published: March 2018

Abstract
A brief review of the mathematical methods of thin-film growth simulation and results of their applications is presented. Both full-atomistic and multi-scale approaches that were used in the studies of thin-film deposition are considered. The results of the structural parameter simulation including density profiles, roughness, porosity, point defect concentration, and others are discussed. The application of the quantum level methods to the simulation of the thin-film electronic and optical properties is considered. Special attention is paid to the simulation of the silicon dioxide thin films.
Orbital Period Variations in the NY Vir System, Revisited in the Light of New Data
Authors: Baştürk Özgür , Esmer Ekrem Murat 
Published: March 2018

Abstract
NY Virginis is an eclipsing binary system with a subdwarf B primary and an M type dwarf secondary. Recent studies (Qian et al. 2012; Lee et al. 2014) suggested the presence of two circumbinary planets with a few Jovian masses within the system. Lee et al. (2014) examined the orbital stabilities of the suggested planets, using the best-fit parameters derived from their eclipse timing variation analysis. They found that the outer companion should be ejected from the system in about 800 000 years. An observational report from Pulley et al. (2016) pointed out that the recent mideclipse times of the binary deviate significantly from the models suggested by Lee et al. (2014). In fact, variations in the orbital period of the system had already been recognized by many authors, but the parameters of these variations vary significantly as new data accumulate. Here, we analyze the eclipse timing variations of the NY Vir system, using new mid-eclipse times that we have obtained together with earlier published measurements in order to understand the nature of the system and constrain its parameters.
Interest rate rules and equilibrium (in)determinacy in a small open economy: the role of internationally traded capital
Authors: Chang Wen-ya , Tsai Hsueh-fang , Chang Juin-jen , Lin Hsieh-yu 
Published: March 2018

Abstract
This study develops a small-open-economy version of Benhabib, J., S. Schmitt-Grohé, and M. Uribe. 2001. “Monetary Policy and Multiple Equilibria.” American Economic Review 91: 167–186. We systematically explore the role of international capital mobility and the portfolio balance channel in terms of macroeconomic (in)stability when the government follows a commonly-adopted interest-rate feedback rule. In a one-traded-good model, the steady-state equilibrium, in general, is locally determinate; international capital mobility stabilizes the economy against business cycle fluctuations under a simple interest-rate feedback rule. In a two-good (traded and non-traded goods) model, the relationship between equilibrium (in)determinacy and the aggressiveness of interest rate rules is not monotonic, and crucially depends on households’ portfolio preferences. These results suggest that a unified interest rate rule can end up with very different consequences of macroeconomic (in)stability in an open economy from those in a closed economy.