bluuebunny/crossref_metadata_2025_split huggingface dataset:
Onset and Duration of Anesthesia of Varying Lidocaine and Epinephrine Concentrations Used in WALANT
Authors: Balgos Michael Paul , Magtoto Ian Jason 
Published: November 2024

Background. Wide awake local anesthesia no tourniquet (WALANT) is an increasingly popular anesthetic technique used in hand surgery which uses local anesthetic and epinephrine, achieves adequate anesthesia, and eliminates the need for a tourniquet.
Objective. This study compares the onset and duration of the three most commonly used concentrations of lidocaine and epinephrine for WALANT.
Methodology. This was a randomized double-blind comparative study of 78 middle fingers subjected to either 1% lidocaine with 1:100,000 epinephrine, 0.5% lidocaine with 1:200,000 epinephrine or 0.25% lidocaine with 1:400,000 epinephrine. The pinprick test was used to measure onset time and anesthetic duration for the local effect and as a digital nerve block.
Results. The contents of each treatment arm were as follows: Arm A: 0.25% lidocaine with 1:400,000 epinephrine, Arm B: 1% lidocaine with 1:100,000 epinephrine, and Arm C: 0.5% lidocaine with 1:200,000 epinephrine. Arm B had the shortest onset time (30.77 ± 10.39 seconds for local, 2.78 ± 0.69 minutes for digital block) followed by Arm C (38 ± 17.17 seconds for local, 4.30 ± 1.62 minutes for digital block) and Arm A (55.38 ± 18.48 seconds for local, 5.18 ± 1.46 minutes for digital block, p <0.001). A longer duration of anesthesia was achieved in both local and digital blocks for Arm B (5.07 ± 0.34 hours for local, 4.26 ± 0.33 hours for digital block) followed by Arm C (4.44 ± 0.31 hours for local, 3.36 ± 0.24 hours for digital block) then Arm A (3.01 ± 0.33 hours for local, 2.29 ± 0.29 hours for digital block, p <0.001).
Conclusion. Higher concentrations of lidocaine and epinephrine provided faster onset and longer duration of anesthesia for both local block and digital nerve block. Lower concentrations in higher volumes may be sufficient for short procedures (less than three hours).
Comparing the Effectiveness of Surgical versus Medical Approaches in Managing Patients with Indeterminate Spinal Instability Neoplastic Scores
Authors: Wooden Lou Ides , Silverio Immanuel , Tangente Ronald 
Published: November 2024

Background. Treating indeterminate cases of spinal metastases (those with spinal instability neoplastic score [SINS] of 7–12) remains a clinical dilemma, as there are currently no well-defined recommendations for this category. This study aimed to identify the most appropriate approach for patients with indeterminate SINS by reviewing and analyzing published evidence.
Objective. To determine the effectiveness of surgical and medical approaches in managing spinal metastasis with indeterminate SINS.
Methodology. A comparative effectiveness study was conducted using systematic review and meta-analysis. A systematic search was performed in the following databases: PubMed, Embase, Cochrane Library, and Google Scholar. Studies were selected based on inclusion and exclusion criteria comparing surgical and medical approaches for indeterminate SINS. The outcomes analyzed were patients’ functional status, complications, and conversion to surgery/revision surgery. Quantitative data were analyzed using Review Manager version 5.3 software, and results were reported using a forest plot.
Results. Eight studies were included in the qualitative review, and six were included for quantitative synthesis, involving 1,312 patients. In patients with spinal metastasis with indeterminate SINS, surgery resulted in less functional decline than medical management, with a pooled odds ratio (OR) of 0.50 (95% CI: 0.31, 0.81). However, significantly more complications were associated with surgery (OR of 2.6; 95% CI: 1.66, 4.08). The authors reported a pooled result of 21.19% conversion to surgery among those initially managed with a medical approach. In the initial surgery group, there was a significant reduction in conversion to surgery or revision surgery, with an OR of 0.19 (95% CI: 0.10, 0.34).
Conclusion. This study addresses the dilemma of treating spinal metastasis with indeterminate instability, advocating for surgery as the primary intervention due to its potential to improve functional outcomes and provide a satisfactory quality of life, which may, in turn, influence overall survival. This topic can be explored further including identifying a specific SINS threshold that could serve as a criterion for recommending surgery.
ПЕРЦЕПТИВНОЕ ВОПЛОЩЕНИЕ КОНЦЕПТА БРЕСТСКАЯ КРЕПОСТЬ В ЯЗЫКОВОМ СОЗНАНИИ ЖИТЕЛЕЙ БРЕСТСКОГО РЕГИОНА (ПО ДАННЫМ НАПРАВЛЕННОГО АССОЦИАТИВНОГО ЭКСПЕРИМЕНТА)
Authors: И.Л. Ильичева 
Published: November 2024

Статья посвящена описанию перцептивного образа лингво-культурного концепта в языковом сознании жителей Брестского региона. Основной метод исследования – направленный ассоциативный эксперимент с применением методики моделирования когнитивных профилей. В результате количественной обработки полученных реакций выявлены ядерные и периферийные ольфактор-ные, аудиальные и хроматологические реакции. Делается вывод о том, что в со-знании жителей Брестского региона анализируемый концепт репрезентиро-ван большим количеством когнитивных признаков, что свидетельствует о его коммуникативной релевантности.
The article is devoted to the description of the perceptual image of the linguistic and cultural concept in the linguistic consciousness of the inhabitants of the Brest region. The principal method of research is a directed associative experiment with the usage of the modeling cognitive profiles method. As a result of quantitative processing of the obtained reactions, nuclear and peripheral olfactory, auditory and chromatological reactions were identified. It is concluded that in the minds of resi-dents of the Brest region, the analyzed concept is represented by a large number of cognitive features, which indicates its communicative relevance.
МЕЛОДИЯ ДОРОГА В ТВОРЧЕСТВЕ МАРИИ ВАГАТОВОЙ (ВОЛДИНОЙ)
Authors: А.Н. Семёнов 
Published: November 2024

В статье исследуется содержательное наполнение мелодии дорога в творчестве Марии Кузьминичны Вагатовой (Волдиной). Как семанти-ческое и ладовое целое мелодия является одной из семи составляющих идей-но-тематического содержания художественных произведений поэтессы-скази-тельницы. Работа выстроена как последовательное развитие и обоснование утверждения, согласно которому авторское толкование дороги в лирическом и эпическом пространстве М. Вагатовой (Волдиной) – это не только тема, но и идея, представляющая понимание направленности и смысла жизни. Тематиче-ское решение и идейная трактовка данной мелодии выступают в качестве одно-го из самых репрезентативных показателей того, как поэтесса понимает сущ-ность жизненного пути, его содержание и направленность, его параллели и пересечения. Доказывается, что мелодия дорога в конкретных художественных текстах обретает сакральное звучание: она звучит на земле, на воде и в небе, что составляет содержание родного края. Основной посыл статьи строится на том, что дорога в художественном сознании человека, живущего в суровых условиях Севера, есть один из наиболее действенных способов определения свое-го жизненного пути, формирования условий для своего гармоничного существо-вания и сосуществования с окружающим миром. Последнее является важнейшей составной частью художественного сознания хантыйской сказительницы-поэта, и эта составляющая имеет корни в художественном сознании народа ханты.
The article examines the content of the melody of ROAD in oeuvre of Maria Kuzminichna Vagatova (Voldina). As a semantic and modal unity, the melody is one of the seven components of the ideological and thematic content of the poet-storyteller artistic works. The study is structured as a consistent development and jus-tification of the statement according to which the author's interpretation of the road in the lyrical and epic space by M. Vagatova (Voldina) is not only a theme, but also an idea representing an understanding of the orientation and meaning of life. The themat-ic solution and the ideological interpretation of this melody act as one of the most rep-resentative indicators of how the poetess understands the essence of the life path, its content and orientation, its parallels and intersections. It is proved that the melody of the road in specific artistic texts acquires a sacred sound: it sounds on the ground, on the water and in the sky, which is the content of the native land. The main message of the article is grounded by the fact that the road in the artistic consciousness of a per-son living in the harsh conditions of the North is one of the most effective ways to determine his life path, create conditions for his harmonious existence and coex-istence with the outside world. The latter is the most important component of the artistic consciousness of the Khanty storyteller-poet, and this component has roots in the artistic consciousness of the Khanty people.
«ОМСКИЕ» ГЛАВЫ В КНИГЕ К. ВАНЕКА «ПРИКЛЮЧЕНИЯ ШВЕЙКА В РУССКОМ ПЛЕНУ»
Authors: О.Л. Гиль 
Published: November 2024

Статья посвящена анализу «омских» глав в продолжении кни-ги Я. Гашека «Похождения бравого солдата Швейка во время мировой войны», со-зданном К. Ванеком. Определяются особенности изображения в произведении образов омичей и отражения реальных событий, а также преемственность по-вествования о Первой мировой войне с традицией сатирической литературы средневековья и Возрождения. Выявляются ключевые фигуры «омских» глав, роль и формы комического в «Приключениях Швейка в русском плену», рассмат-риваются основные типы и способы их характеристики, аллюзии на «Корабль ду-раков» С. Бранта. Научная новизна работы заключается в обращении к материалу, который ранее не становился предметом внимания отечественного литературо-ведения. В работе используются биографический, культурно-исторический, срав-нительно-сопоставительный и историко-типологический методы. Делается вы-вод о взаимосвязи «омских» глав книги К. Ванека с европейской литературной традицией.
The article is devoted to the analysis of the “Omsk” chapters in the se-quel of the book by J. Hašek “The Adventures of the brave soldier Švejk during the World War”, created by K. Vanek. The features of the depiction of the images of the Omsk people and the reflection of real events in the work are determined, as well as the continuity of the narrative about the First World War with the tradition of satirical literature of the Middle Ages and Renaissance. The key figures of the “Omsk” chapters, the role and forms of the comic in “The Adventures of Schweik in Russian captivity” are revealed, the main types and ways of their characteristics, allusions to S. Brant's “Ship of Fools” are considered. The scientific novelty of the work lies in the appeal to material that has not previously been the subject of attention of Russian literary criticism. The work uses biographical, cultural-historical, compara-tive and historical-typological methods. The conclusion is made about the relationship of the “Omsk” chapters of K. Vanek's book with the European literary tradition.
РЕЦЕНЗИЯ НА КНИГУ: ЮРИЙ ВЭЛЛА. ИЗБРАННОЕ: СОБРАНИЕ СОЧИНЕНИЙ В 3-Х ТОМАХ. ХМАО – ЮГРА, 2024
Authors: Д.Д. Терентьева 
Published: November 2024

Рецензия содержит общую характеристику собрания сочине-ний Ю.К. Вэллы (2024), адресованного широкому кругу читателей: научным ра-ботникам, студентам, школьникам и всем, кому интересна родная литература, культура, история Ханты-Мансийского автономного округа. Составители данного издания представляют широкий диапазон творчества Юрия Вэллы и публикаций о нем. К числу безусловных достоинств издания относятся широта представ-ленного материала, тонкие наблюдения составителей особенностей творче-ства ненецкого писателя и поэта Ю.К. Вэллы. Делается вывод о востребованности сборника в силу сочетания в нем художественного, биографического и литератур-но-критического материала, образности и выразительности авторского стиля.
The review contains a general characterization of the collection of works by Y.K. Vella (2024), addressed to a wide range of readers: researchers, stu-dents, schoolchildren and all those who are interested in native literature, culture, his-tory of the Khanty-Mansi Autonomous Okrug. The compilers of this edition present a broad overview of Yuri Vella's work and publications about him. Among the undoubted advantages of the edition are the breadth of the presented material; subtle observations of the compilers on the peculiarities of the Nenets writer and poet Y.K. Vella. It is con-cluded that the collection is in demand due to the combination of artistic, biographical and literary-critical material, imagery and expressiveness of the author's style.
ANÁLISE DA ADESÃO À PROFILAXIA DE HEMOFÍLICOS “A” - UMA REVISÃO DE LITERATURA
Authors: Silva Leidyanne Karolaine Barbosa da , Santos Maria Eduarda Farias da Silva , Lacerda Amanda Magalhães Máximo , Aragão Ricardo Victor Ramos de Amorim , Silva Letícia Santos da , Maciel Anna Beatriz de Bulhões , Almeida Ewerton Igor Alves de , Silva Bianca Mirele Targino da , Silva Yasmim Meneses , Melo Jhulia Katharine Vieira Almeida de 
Published: November 2024

A Hemofilia A é uma doença genética rara causada pela deficiência do fator VIII que pode desencadear sangramentos gengivais, hematomas e hemartrose. O tratamento é feito com medicamentos específicos fornecidos pelo Sistema Único de Saúde, mas, interferências na adesão desse processo podem acarretar um declínio na qualidade de vida do paciente. Com isso, o objetivo deste trabalho foi realizar uma revisão de literatura a fim de avaliar a adesão à profilaxia de hemofílicos em uso de fator VIII à partir da Escala Validada de Adesão ao Tratamento do Regime de Hemofilia - Profilaxia (VERITAS-PRO). Para tal, foi realizado um levantamento bibliográfico do período de 2018 a 2023 nas bases de dados Medline, Pubmed e Biblioteca Virtual de Saúde MS (BVS), abordando várias singularidades, como faixa etária, ambiente habitacional, doenças coexistentes, entre outras. Apesar dos resultados indicarem uma adesão satisfatória, foram identificadas conformidades abaixo do limite estabelecido pela escala VERITAS-PRO, impactando não apenas a saúde física, mas também a qualidade de vida e as relações interpessoais dos pacientes. As disparidades observadas entre diferentes populações ressaltam a necessidade premente de considerar contextos culturais e sistemas de saúde específicos. Sendo necessário abordagens que contribuam para estratégias mais eficazes de gestão e intervenção na hemofilia A, assim, garantindo maior incentivo ao conhecimento da doença e promovendo a conscientização sobre a importância da adesão ao tratamento.
Apontamento sobre o Sistema de Cooperação para o Desenvolvimento a partir de Dados do Caso Moçambicano
Authors: De Moçambique Universidade Católica 
Published: November 2024

O sistema de Cooperação para o Desenvolvimento tem registado progressos assinaláveis no sentido de uma maior inter-relação entre as comunidades formalmente organizadas e de uma maior atenção à eficácia das acções desencadeadas. Ainda assim continua por fazer a conciliação com os contextos que marcam cada um dos países alvo. Uma das grandes lacunas tem sido a perspectiva que a mudança social se pode fazer num curto espaço de tempo, quando historicamente e sociologicamente esta só é possível numa ou várias gerações. Os efeitos perversos resultantes desta lacuna fazem-se sentir nos diferentes sectores tidos como chave para o desenvolvimento. Destacamos aqui o caso da educação em Moçambique.
The Cooperation for Development system has made notable progress both in terms of creating a greater level of interaction among formally organized communities and in terms of paying greater attention to the efficiency of actions in progress. However, there is still a lack of correspondence between the context of target countries and planned actions. One of the weaknesses of cooperation programs has been the belief that social changes can be affected within a short period of time, when, in fact, historically and sociologically, such changes can only be made over generations. This belief has produced some perverse results in actions in key areas of development. In this study, we highlight the particular effects of this belief on actions in education in Mozambique.
A Independência do Poder Judicial: um Desafio para a Consolidação do Estado de Direito em Moçambique?
Authors: De Moçambique Universidade Católica 
Published: November 2024

O artigo resulta duma investigação que procura introduzir no debate académico o modo como é exercido o poder judicial moçambicano. Considerando que, neste país, o Estado de Direito Democrático ainda é um processo em construção, e sendo que nesse modelo estadual é indispensável a separação e independência de poderes, procurou-se realizar uma primeira aproximação às concepções e práticas dos actores que participam, no exercício do poder judicial. O questionamento mobilizado centrou-se, preferencialmente, na independência do poder judicial, procurando-se clarificar, do ponto de vista conceptual e empírico, o modo como os principais garantes do Estado de Direito contribuiem no processo de consolidação do Estado de Direito em Moçambique. A metodologia utilizada consistiu na análise de fontes secundárias e primárias, como em trabalho de campo e posterior análise empirica de dados. Para além de uma revisão da literatura especializada, convocaram-se as seguintes técnicas de recolha de dados: (i) análise documental e (ii) entrevistas semi-estruturadas aos principias actores deste processo de consolidação do Estado de Direito. Os principais resultados, no quadro deste questionamento, indicam que o processo de consolidação do Estado de Direito ainda revela algumas contradições e ambivalências.
This paper is the result of research which aims to stimulate academic debate on the question of how judicial power is exercised in Mozambique. Taking into account that the creation of a state of democratic law is still in the process of construction in the country, and the fact that such a state model depends on the separation and independence of powers, this study seeks to obtain an outline of the concepts and practices of the actors involved in the exercise of judicial power. The central question focuses on the independence of the judiciary and aims to clarify, from both a conceptual and empirical standpoint, how the principal sponsors of the state of law contribute towards the process of consolidating a state of law in Mozambique. The methodology used involved the analysis of primary and secondary sources taken from data gathered in the field followed by empirical data analysis. In addition to a literature review, data collection was carried out via a) document analysis and b) semi-structured interviews with the principal actors engaged in the process of consolidating the state of law. Findings indicate that some contradictions and ambiguities still exist within the process of consolidating a state of law.
O Turismo como Estratégia Privilegiada para promover um Desenvolvimento Social Inclusivo - Estudo multi-caso (Pemba, Moçambique)
Authors: De Moçambique Universidade Católica 
Published: November 2024

A Organização Mundial de Turismo (OMT, 1996), organização que superintende o turismo, realça o papel desta actividade humana como sendo uma das actividades promissoras no campo do desenvolvimento económico e social. Por sua vez, o Relatório de Desenvolvimento Humano (RDU, 2013) considera que o “desenvolvimento social” visa melhorar os indicadores de bem-estar económico e social e aumentar a qualidade de vida das pessoas e das comunidades. É neste contexto que se inscreve o presente estudo, procurando explorar as potencialidades desta relação. O principal objectivo do estudo foi perceber como é que os diversos actores locais participam neste processo de desenvolvimento do turismo. Neste sentido, optámos por um estudo multi-caso, recorrendo a um conjunto de técnicas de recolha e análise de dados: análise documental, entrevistas semi-estruturadas e observação não participante. A resposta, dada à problemática em estudo, sugere que as comunidades locais tendem a não ser envolvidas neste processo, como actores que devem tomar parte activa na tomada de decisão. Com efeito, o investimento no turismo, como estratégia de desenvolvimento social inclusivo, passa, inevitavelmente, pelo modo como os diversos actores, implicados neste processo, são chamados a participar enquanto “actores capazes”, reconhecendo-lhes os seus direitos culturais.
The World Tourism Organization (UNWTO) which regulates tourism, distinguishes the role of this human activity as being a promising activity within the field of economic and social development. The Human Development Report (2013) considers ‘social development’ as a mechanism for improving the indicators of social and economic well-being and quality of life of people and their communities. It is within this context that this study aims to explore the potential of this relationship. The principal objective of this study was to understand how various local actors participate in the process of tourism development. We chose a multi-case study methodology using a set of data collection and analysis instruments: document analysis, semi-structured interviews and non-participant observation. Findings indicate that local communities tend not to be involved in tourism development process as actors who ought to take part in the decision-making process. Investment in tourism as a viable socially inclusive development strategy is, in reality, related to the way in which participants are only involved, and their cultural rights respected, when they are perceived as ‘capable actors’ in the process.
Solution‐Processed Bilayer Dielectrics for Flexible Low‐Voltage Organic Field‐Effect Transistors in Pressure‐Sensing Applications
Authors: Yin Zhigang , Yin Ming‐Jie , Liu Ziyang , Zhang Yangxi , Zhang A. Ping , Zheng Qingdong 
Published: July 2018

AbstractFlexible pressure sensors based on organic field‐effect transistors (OFETs) have emerged as promising candidates for electronic‐skin applications. However, it remains a challenge to achieve low operating voltages of hysteresis‐free flexible pressure sensors. Interface engineering of polymer dielectrics is a feasible strategy toward sensitive pressure sensors based on low‐voltage OFETs. Here, a novel type of solution‐processed bilayer dielectrics is developed by combining a thick polyelectrolyte layer of polyacrylic acid (PAA) with a thin poly(methyl methacrylate) (PMMA) layer. This bilayer dielectric can provide a vertical phase separation structure from hydrophilic interface to hydrophobic interface which adjoins well to organic semiconductors, leading to improved stability and remarkably reduced leakage currents. Consequently, OFETs using the PMMA/PAA dielectrics reveal greatly suppressed hysteresis and improved mobility compared to those with a pure PAA dielectric. Using the optimized PMMA/PAA dielectric, flexible OFET‐based pressure sensors that show a record high sensitivity of 56.15 kPa−1 at a low operating voltage of −5 V, a fast response time of less than 20 ms, and good flexibility are further demonstrated. The salient features of high capacitance, good dielectric performance, and excellent reliability of the bilayer dielectrics promise a bright future of flexible sensors based on low‐voltage OFETs for wearable electronic applications.