bluuebunny/crossref_metadata_2025_split huggingface dataset:
Increased amygdala-visual cortex connectivity in youth with persecutory ideation
Authors: DeCross Stephanie N. , Farabaugh Amy H. , Holmes Avram J. , Ward Maeve , Boeke Emily A. , Wolthusen Rick P. F. , Coombs Garth , Nyer Maren , Fava Maurizio , Buckner Randy L. , Holt Daphne J. 
Published: February 2019

AbstractBackgroundSubclinical delusional ideas, including persecutory beliefs, in otherwise healthy individuals are heritable symptoms associated with increased risk for psychotic illness, possibly representing an expression of one end of a continuum of psychosis severity. The identification of variation in brain function associated with these symptoms may provide insights about the neurobiology of delusions in clinical psychosis.MethodsA resting-state functional magnetic resonance imaging scan was collected from 131 young adults with a wide range of severity of subclinical delusional beliefs, including persecutory ideas. Because of evidence for a key role of the amygdala in fear and paranoia, resting-state functional connectivity of the amygdala was measured.ResultsConnectivity between the amygdala and early visual cortical areas, including striate cortex (V1), was found to be significantly greater in participants with high (n= 43)v.low (n= 44) numbers of delusional beliefs, particularly in those who showed persistence of those beliefs. Similarly, across the full sample, the number of and distress associated with delusional beliefs were positively correlated with the strength of amygdala-visual cortex connectivity. Moreover, further analyses revealed that these effects were driven by those who endorsed persecutory beliefs.ConclusionsThese findings are consistent with the hypothesis that aberrant assignments of threat to sensory stimuli may lead to the downstream development of delusional ideas. Taken together with prior findings of disrupted sensory-limbic coupling in psychosis, these results suggest that altered amygdala-visual cortex connectivity could represent a marker of psychosis-related pathophysiology across a continuum of symptom severity.
Machine learning in mental health: a scoping review of methods and applications
Authors: Shatte Adrian B. R. , Hutchinson Delyse M. , Teague Samantha J. 
Published: February 2019

AbstractBackgroundThis paper aims to synthesise the literature on machine learning (ML) and big data applications for mental health, highlighting current research and applications in practice.MethodsWe employed a scoping review methodology to rapidly map the field of ML in mental health. Eight health and information technology research databases were searched for papers covering this domain. Articles were assessed by two reviewers, and data were extracted on the article's mental health application, ML technique, data type, and study results. Articles were then synthesised via narrative review.ResultsThree hundred papers focusing on the application of ML to mental health were identified. Four main application domains emerged in the literature, including: (i) detection and diagnosis; (ii) prognosis, treatment and support; (iii) public health, and; (iv) research and clinical administration. The most common mental health conditions addressed included depression, schizophrenia, and Alzheimer's disease. ML techniques used included support vector machines, decision trees, neural networks, latent Dirichlet allocation, and clustering.ConclusionsOverall, the application of ML to mental health has demonstrated a range of benefits across the areas of diagnosis, treatment and support, research, and clinical administration. With the majority of studies identified focusing on the detection and diagnosis of mental health conditions, it is evident that there is significant room for the application of ML to other areas of psychology and mental health. The challenges of using ML techniques are discussed, as well as opportunities to improve and advance the field.
Nudging in Neonatology: Practical Wisdom and Accountability for Reasonableness
Authors: Stanak Michal 
Published: February 2019

ObjectivesThe way choice is presented has an impact on decision-making. This is the case also in the context of neonatal intensive care units (NICUs), particularly in the challenging cases that concern the limit of viability. The objective of this article is to examine the role of nudging in the shared decision-making in neonatology and elaborate on the respective moral challenges.ResultsNudging is not morally neutral. There are two key sources of ethical issues at the heart of nudging. The first one concerns the lack of transparency, while the second concerns the background value judgments that are imminent whenever nudging is used for achieving a particular end. To solve the underlying conflict, a virtue ethics approach combined with the accountability for reasonableness framework is suggested to guide the use of the tool of nudging.ConclusionsNICU professionals ought to use the tool of nudging transparently in line with their act of profession and their practically wise judgment.
Treatment exposures stratify need for echocardiographic screening in asymptomatic long-term survivors of hematopoietic stem cell transplantation
Authors: Rotz Seth J. , Powell Adam , Myers Kasiani C. , Taylor Michael D. , Jefferies John L. , Lane Adam , El-Bietar Javier A. , Davies Stella M. , Dandoy Christopher E. , Ryan Thomas D. 
Published: February 2019

AbstractWe sought to define the prevalence of echocardiographic abnormalities in long-term survivors of paediatric hematopoietic stem cell transplantation and determine the utility of screening in asymptomatic patients. We analysed echocardiograms performed on survivors who underwent hematopoietic stem cell transplantation from 1982 to 2006. A total of 389 patients were alive in 2017, with 114 having an echocardiogram obtained ⩾5 years post-infusion. A total of 95 patients had echocardiogram performed for routine surveillance. The mean time post-hematopoietic stem cell transplantation was 13 years. Of 95 patients, 77 (82.1%) had ejection fraction measured, and 10/77 (13.0%) had ejection fraction z-scores ⩽−2.0, which is abnormally low. Those patients with abnormal ejection fraction were significantly more likely to have been exposed to anthracyclines or total body irradiation. Among individuals who received neither anthracyclines nor total body irradiation, only 1/31 (3.2%) was found to have an abnormal ejection fraction of 51.4%, z-score −2.73. In the cohort of 77 patients, the negative predictive value of having a normal ejection fraction given no exposure to total body irradiation or anthracyclines was 96.7% at 95% confidence interval (83.3–99.8%). Systolic dysfunction is relatively common in long-term survivors of paediatric hematopoietic stem cell transplantation who have received anthracyclines or total body irradiation. Survivors who are asymptomatic and did not receive radiation or anthracyclines likely do not require surveillance echocardiograms, unless otherwise indicated.
Evolution of economic scenario generators: a report by the Extreme Events Working Party members
Authors: Jakhria P. , Frankland R. , Sharp S. , Smith A. , Rowe A. , Wilkins T. 
Published: February 2019

Abstract
Some UK insurers have been using real-world economic scenarios for more than 30 years. Popular approaches have included random walks, time series models, arbitrage-free models with added risk premiums or 1-year Value at Risk distribution fits. Based on interviews with experienced practitioners as well as historical documents and meeting minutes, this paper traces historical model evolution in the United Kingdom and abroad. We examine the possible catalysts for changes in modelling practice with a particular emphasis on regulatory and socio-cultural influences. We apply past lessons to provide some guidance to the direction of capital market modelling in future, which has been key for business and strategy decisions.
Ultra-processed foods: what they are and how to identify them
Authors: Monteiro Carlos A , Cannon Geoffrey , Levy Renata B , Moubarac Jean-Claude , Louzada Maria LC , Rauber Fernanda , Khandpur Neha , Cediel Gustavo , Neri Daniela , Martinez-Steele Euridice , Baraldi Larissa G , Jaime Patricia C 
Published: February 2019

AbstractThe present commentary contains a clear and simple guide designed to identify ultra-processed foods. It responds to the growing interest in ultra-processed foods among policy makers, academic researchers, health professionals, journalists and consumers concerned to devise policies, investigate dietary patterns, advise people, prepare media coverage, and when buying food and checking labels in shops or at home. Ultra-processed foods are defined within the NOVA classification system, which groups foods according to the extent and purpose of industrial processing. Processes enabling the manufacture of ultra-processed foods include the fractioning of whole foods into substances, chemical modifications of these substances, assembly of unmodified and modified food substances, frequent use of cosmetic additives and sophisticated packaging. Processes and ingredients used to manufacture ultra-processed foods are designed to create highly profitable (low-cost ingredients, long shelf-life, emphatic branding), convenient (ready-to-consume), hyper-palatable products liable to displace all other NOVA food groups, notably unprocessed or minimally processed foods. A practical way to identify an ultra-processed product is to check to see if its list of ingredients contains at least one item characteristic of the NOVA ultra-processed food group, which is to say, either food substances never or rarely used in kitchens (such as high-fructose corn syrup, hydrogenated or interesterified oils, and hydrolysed proteins), or classes of additives designed to make the final product palatable or more appealing (such as flavours, flavour enhancers, colours, emulsifiers, emulsifying salts, sweeteners, thickeners, and anti-foaming, bulking, carbonating, foaming, gelling and glazing agents).
Food-based dietary guidelines of Arabic-speaking countries: a culturally congruent profile
Authors: Coats Laura , Bernstein Joshua , Dodge Elizabeth , Bechard Lori , Aboul-Enein Basil H 
Published: February 2019

AbstractObjectiveDietary guidelines for food groups, types and portion sizes are common practice at the national level. As the relationship between nutrition and disease and the influence of cultural identity on individual behaviour become clearer, dietary guidelines necessarily evolve. Today, the Arabic-speaking region is experiencing a dual burden of undernutrition and increasing rates of overweight and obesity. Cultural congruency among dietary guidelines in the Arabic-speaking region and how they affect health education, health promotion, and nutrition programme planning or individual dietary behaviours have yet to be examined. The present work provides dietitians and public health professionals a narrative review of proposed food guidelines for the Arabic-speaking region.DesignThe current review examined five established dietary guidelines within the Arabic-speaking region, namely the Arab Food Dome (Arab Gulf states), the Healthy Food Palm (Saudi Arabia), the Lebanese Dietary Guidelines, the Omani Guide to Healthy Eating and the Qatar Dietary Guidelines, and compared findings with the regional Eastern Mediterranean guidelines developed by the WHO. Individual guideline recommendations are tabled for comparative review.SettingThe Arabic-speaking region.ParticipantsRespective Arabic-speaking populations.ResultsHealth educators, community health practitioners and nutrition professionals can benefit from the cultural contexts associated with dietary guidelines in this region.ConclusionsCommunity-level policy and individual behaviour change will benefit from cultural sensitivity; health communication and behaviour change programming require cultural competence provided in the present review; and programme evaluation efforts (prior to and after implementation) should include a detailed understanding of how culture shapes regional policy and individual nutrition behaviours.
A Gill Histopathology Study in two Native Fish Species from the Hydrographic Douro Basin
Authors: Santos Dércia , Luzio Ana , Coimbra Ana M. , Varandas Simone , Fontaínhas-Fernandes António , Monteiro Sandra M. 
Published: February 2019

AbstractGill histopathology is a valuable tool to evaluate ecosystems health, because the gill is a key site of waterborne pollutant uptake and the first target organ to their toxicity. Consequently, this makes it important in biomonitoring programs. This study aims to evaluate gill histopathological differences in Douro basin native fish species and determine possible associations with water quality and the ecological status classifications. Two native fish species (Pseudochondrostoma duriense and Luciobarbus bocagei) were sampled in four points of the Douro basin: two reference points, Ameixiosa (Paiva River) and Covelas (Bestança River), both classified with an excellent ecological status; and two disturbed points, Castro Daire (Paiva River) and Alvações do Corgo (Corgo River), categorized with a good and a moderate ecological status, respectively. Gill histopathological differences were qualitative and quantitatively analyzed. The histological analysis showed that, in all sampling locations, both species presented some degree of gill differences, such as epithelial lifting, lamellar fusion, and/or necrosis. The histopathological differences evaluation emphasized some variances in the responses between the two species. In nase, the filament and lamellar epithelium proliferation were the histopathological differences that better reflected the river ecological status classification, proving their usefulness in biomonitoring programs.
Permaculture farmers consistently cultivate perennials, crop diversity, landscape heterogeneity and nature conservation
Authors: Hirschfeld Sarah , Van Acker Rene 
Published: February 2019

AbstractPermaculture is an international sustainability movement and agroecological design system. Using ecological management practices and locally-adapted solutions, permaculture claims to benefit several ecosystem services including provisioning of diverse crop yields, regulating hydrological cycles and soil quality, supporting wildlife conservation, and biocontrol of pests, weeds and diseases. Despite limited attention by the academic community, grassroots permaculture adoption has been reported in at least 45 countries worldwide thus creating a unique opportunity for in-situ research. This study characterized plant communities on ten applied permaculture farms and found that independent adopters consistently implemented predominately perennial species (73% of species richness), polycultures (mean 42 crop species per site), and zone design. These practices resulted in commercial farms characterized by perennialization, crop diversification, landscape heterogeneity and nature conservation. Grassroots adopters were remarkably consistent in their interpretation and application of an unregulated agricultural model suggesting that such movements may exert considerable influence over local agroecological transitions. While this characterization does not provide an exhaustive depiction of applied permaculture, it is recommended that future research acknowledge these traits as a minimum for study designs investigating the effects of permaculture management on ecosystem function.
Multivariate credibility modelling for usage-based motor insurance pricing with behavioural data
Authors: Denuit Michel , Guillen Montserrat , Trufin Julien 
Published: February 2019

AbstractPay-how-you-drive (PHYD) or usage-based (UB) systems for automobile insurance provide actuaries with behavioural risk factors, such as the time of the day, average speeds and other driving habits. These data are collected while the contract is in force with the help of telematic devices installed in the vehicle. They thus fall in the category of a posteriori information that becomes available after contract initiation. For this reason, they must be included in the actuarial pricing by means of credibility updating mechanisms instead of being incorporated in the score as ordinary a priori observable features. This paper proposes the use of multivariate mixed models to describe the joint dynamics of telematics data and claim frequencies. Future premiums, incorporating past experience can then be determined using the predictive distribution of claim characteristics given past history. This approach allows the actuary to deal with the variety of situations encountered in insurance practice, ranging from new drivers without telematics record to contracts with different seniority and drivers using their vehicle to different extent, generating varied volumes of telematics data.
“Safe areas”: The international legal framework
Authors: Gillard Emanuela-Chiara 
Published: February 2019

AbstractIn recent years there have been repeated calls for the establishment of so-called “safe areas” to protect civilians from the effects of hostilities in a number of contexts. The present article presents the international law framework relevant to the establishment and operation of such areas: the provisions of international humanitarian law on protected zones; the rules regulating resort to armed force, Security Council authorization and mandates for the establishment of such areas by multinational forces in the absence of agreement between belligerents; and the refugee and international human rights issues raised by such zones. Using the example of the “protection of civilians sites” in South Sudan, the article then highlights some of the operational challenges raised by safe areas. It concludes with some reflections on how to enhance the likelihood that belligerents will establish such protected zones in the future.
First Report of Kochia (Bassia scoparia) with Cross-Resistance to Dicamba and Fluroxypyr in Western Kansas
Authors: Kumar Vipan , Currie Randall S. , Jha Prashant , Stahlman Phillip W. 
Published: February 2019

AbstractEvolution and rapid spread of herbicide-resistant (HR) kochia has become a significant challenge for growers in the U.S. Great Plains. The main objectives of this research were to confirm and characterize the response of putative auxinic HR (Aux-HR) kochia accessions (designated as KS-4A, KS-4D, KS-4H, KS-10A, KS-10-G, and KS-10H) collected from two different corn fields near Garden City, KS, to dicamba and fluroxypyr and to determine the EPSPS gene copy number to detect whether those accessions were also resistant to glyphosate. Single-dose experiments indicated that putative Aux-HR kochia accessions had 78% to 100% and 85% to 100% survivors when treated with dicamba (560 g ae ha−1) and fluroxypyr (235 g ae ha−1), respectively. Whole-plant dicamba dose–response studies revealed that the selected Aux-HR accessions had 2.9- to 15.1- and 3.1- to 9.4-fold resistance to dicamba relative to two susceptible accessions (MT-SUS and KS-SUS). In a separate fluroxypyr dose–response experiment, the selected Aux-HR accessions also exhibited 3.8- to 7.3- and 3.0- to 8.6-fold resistance to fluroxypyr on the basis of shoot fresh and dry weight responses, respectively. The confirmed Aux-HR kochia accessions also had 3 to 13 EPSPS gene copies relative to MT-SUS and KS-SUS accessions (each with 1 EPSPS gene copy). These results suggest that the putative Aux-HR kochia accessions from Kansas had developed moderate to high levels of cross-resistance to dicamba and fluroxypyr and low to high levels of resistance to glyphosate. This is the first confirmation of kochia accessions with cross-resistance to dicamba and fluroxypyr in Kansas. Growers should use diverse kochia control programs, including the proper use of dicamba and fluroxypyr stewardship, use of cover crops, occasional tillage, diversified crop rotations, and alternative effective herbicides to prevent further evolution and spread of Aux-HR kochia on their fields.
Integrating Behavioral Science With Mobile (mHealth) Technology to	Optimize Health Behavior Change Interventions
Authors: Walsh Jane C. , Groarke Jenny M. 
Published: February 2019

Abstract. Recent rapid advances in technology have provided us with a golden opportunity to effect change in health-related outcomes for chronic disease by employing digital technologies to encourage and support behavior change to promote and maintain health. Behavior change theories are the bedrock to developing evidence-based mHealth interventions. Digital technologies enable researchers to empirically test behavioral theories in “real-world” contexts using behavior change techniques ( Hekler, Michie, et al., 2016 ). According to the European Commission (2014) among the world’s population of 7 billion, there are over 5 billion mobile devices and over 90% of the users have their mobile device near them 24 hr a day. This provides a huge opportunity for behavior change and one that health psychologists have already begun to address. However, while a novel and exciting area of research, many early studies have been criticized for lacking a strong evidence base in both design and implementation. The European Commission conducted a public consultation in 2016 on the issues surrounding the use of mHealth tools (e.g., apps) and found a lack of global standards was a significant barrier. Recently, the World Health Organization (WHO) mHealth Technical Evidence Review Group developed the mHealth evidence reporting and assessment (mERA) checklist for specifying the content of mHealth interventions. Health psychologists play a key role in developing mHealth interventions, particularly in the management of chronic disease. This article discusses current challenges facing widespread integration of mobile technology into self-management of chronic disease including issues around security and regulation, as well as investigating mechanisms to overcoming these barriers.
The Intraseasonal Dynamics of the Mixed Layer Pump in the Subpolar North Atlantic Ocean: A Biogeochemical‐Argo Float Approach
Authors: Lacour L. , Briggs N. , Claustre H. , Ardyna M. , Dall'Olmo G. 
Published: February 2019

AbstractThe detrainment of organic matter from the mixed layer, a process known as the mixed layer pump (ML pump), has long been overlooked in carbon export budgets. Recently, the ML pump has been investigated at seasonal scale and appeared to contribute significantly to particulate organic carbon export to the mesopelagic zone, especially at high latitudes where seasonal variations of the mixed layer depth are large. However, the dynamics of the ML pump at intraseasonal scales remains poorly known, mainly because the lack of observational tools suited to studying such dynamics. In the present study, using a dense network of autonomous profiling floats equipped with bio‐optical sensors, we captured widespread episodic ML pump‐driven export events, during the winter and early spring period, in a large part of the subpolar North Atlantic Ocean. The intraseasonal dynamics of the ML pump exports fresh organic material to depth (basin‐scale average up to 55 mg C·m−2·day−1), providing a significant source of energy to the mesopelagic food web before the spring bloom period. This mechanism may sustain the seasonal development of overwintering organisms such as copepods with potential impact on the characteristics of the forthcoming spring phytoplankton bloom through predator‐prey interactions.