bluuebunny/crossref_metadata_2025_split huggingface dataset:
GUing: A Mobile GUI Search Engine using a Vision-Language Model
Authors: Wei Jialiang , Courbis Anne-Lise , Lambolais Thomas , Xu Binbin , Bernard Pierre Louis , Dray Gérard , Maalej Walid 
Published: November 2024

Graphical User Interfaces (GUIs) are central to app development projects. App developers may use the GUIs of other apps as a means of requirements refinement and rapid prototyping or as a source of inspiration for designing and improving their own apps. Recent research has thus suggested retrieving relevant GUI designs that match a certain text query from screenshot datasets acquired through crowdsourced or automated exploration of GUIs. However, such text-to-GUI retrieval approaches only leverage the textual information of the GUI elements, neglecting visual information such as icons or background images. In addition, retrieved screenshots are not steered by app developers and lack app features that require particular input data.
To overcome these limitations, this paper proposes GUing, a GUI search engine based on a vision-language model called GUIClip, which we trained specifically for the problem of designing app GUIs. For this, we first collected from Google Play app introduction images which display the most representative screenshots and are often captioned (i.e. labelled) by app vendors. Then, we developed an automated pipeline to classify, crop, and extract the captions from these images. This resulted in a large dataset which we share with this paper: including 303k app screenshots, out of which 135k have captions. We used this dataset to train a novel vision-language model, which is, to the best of our knowledge, the first of its kind for GUI retrieval. We evaluated our approach on various datasets from related work and in a manual experiment. The results demonstrate that our model outperforms previous approaches in text-to-GUI retrieval achieving a Recall@10 of up to 0.69 and a HIT@10 of 0.91. We also explored the performance of GUIClip for other GUI tasks including GUI classification and sketch-to-GUI retrieval with encouraging results.
Design of a Low-Cost PMMA/PVAc/PANI Blended Polymers: Structural, Electrical and Dielectric Characteristics
Authors: El-naggar A. M. , Alhaqbani Nourah , Kamal A. M. , Albassam A. A. , Lakshminarayana G. , Mohamed Mohamed Bakr 
Published: November 2024

Polymethyl methacrylate (PMMA)/polyvinyl acetate (PVAc)/tetra-n-butylammonium iodide (TBAI)/x wt % polyaniline (PANI) blended polymers are fabricated using the casting method to operate in energy storage purposes. The structure and morphology of the created blends were studied using X-ray diffraction (XRD) and scanning electron microscope (SEM) techniques. XRD analysis displayed that the semicrystalline behavior of the polymer blend is unaffected by doping. At 293 K and 100 Hz, the dielectric constant decreased from 22.7 (undoped) to 14.04–21.7 depended on the amount of PANI in the doped blend. The greatest energy density (U) values were reported in the blend with x = 0.33; U = 0.00469 J m−3 at 293 K and 100 Hz. Increasing the temperature also improves the U values for all blends. The U values of the doped blends with x = 0.11, 0.22, and 0.33 showed an impressive rise relative to the undoped blend. In the low and intermediate frequency ranges, the ac conductivity increased in the blend with x = 0.44. The correlated barrier hopping (CBH) model was used to describe the electric mechanism of all blends. The influence of the quantity of PANI doping and temperature on electrical impedance spectroscopy, electric modulus, and relaxation time was investigated. A doped blend with x = 0.44 exhibited the greatest dc conductivity; at 343 K. the dc conductivity was increased from 2.477 × 10−8 S m−1 (undoped) to 1.086 × 10−5 S m−1 (x = 0.44). The activation energies (E

a
) for undoped blends varied between 1.36 eV and 1.01 eV based on the temperature range. The amount of PANI added to the host blend controlled the values of E

a
in all samples.
Prevalence and Severity of Sleep Bruxism in Edentulous Patients
Authors: Luchi Klöppel Naiara , Pauletto Patrícia , Meiriely de Almeida Lopes Naiany , Floriani Franciele , Lidani Rangel , De Luca Canto Graziela , Gebler Philippi Analucia , André Mezzomo Luis 
Published: November 2024

Aims: Edentulous patients can also suffer from sleep bruxism (SB), just like dentate patients. This study aims to evaluate the prevalence and severity of SB in edentulous patients using the definitive method.Methods: Twenty‐three edentulous patients underwent treatment with new conventional complete dentures. Definitive SB was evaluated using the Bruxoff (portable electromyography device) while sleeping at home. The prevalence of SB was assessed by the Bruxmeter software, where SB was evaluated as “absent” (score zero), “light” (<2 episodes), “moderate” (between 2 and 4 episodes), or “severe” (>4 episodes). The prevalence was expressed with descriptive statistics in percentage using the number of detected cases out of the total number of patients.Results: Eighteen patients (78.26%) were diagnosed with SB. The severity of SB was 55.5%, 5.5%, and 39% for the light, moderate, and severe scores, respectively.Conclusions: Almost 8 out of 10 edentulous patients have SB. Approximately half of the SB‐detected patients showed moderate to severe severity of bruxism as measured by a commercial, at‐home device.
Spatial and Single-Cell Analyses Reveal Heterogeneity of DNAM-1 Receptor–Ligand Interactions That Instructs Intratumoral γδT-cell Activity
Authors: Wang Xiaolin , Wang Hui , Lu Zhengjing , Liu Xiangjun , Chai Wenjia , Wang Wei , Feng Jun , Yang Shen , Yang Wei , Cheng Haiyan , Chen Chenghao , Zhang Shihan , Sun Nian , Liu Qiaoyin , Li Qiliang , Song Wenqi , Jin Fang , Zeng Qi , Wang Shengcai , Su Yan , Wang Huanmin , Ni Xin , Gui Jingang 
Published: November 2024

Abstract
The dynamic interplay between tumor cells and γδT cells within the tumor microenvironment significantly influences disease progression and immunotherapy outcome. In this study, we delved into the modulation of γδT-cell activation by tumor cell ligands CD112 and CD155, which interact with the activating receptor DNAM-1 on γδT cells. Spatial and single-cell RNA sequencing, as well as spatial metabolomic analysis, from neuroblastoma revealed that the expression levels and localization of CD112 and CD155 varied across and within tumors, correlating with differentiation status, metabolic pathways, and ultimately disease prognosis and patient survival. Both in vivo tumor xenograft experiments and in vitro coculture experiments demonstrated that a high CD112/CD155 expression ratio in tumors enhanced γδT cell–mediated cytotoxicity, whereas a low ratio fostered tumor resistance. Mechanistically, CD112 sustained DNAM-1–mediated γδT-cell activation, whereas CD155 downregulated DNAM-1 expression via E3 ubiquitin ligase tripartite motif–containing 21–mediated ubiquitin proteasomal degradation. By interacting with tumor cells differentially expressing CD112 and CD155, intratumoral γδT cells exhibited varying degrees of activation and DNAM-1 expression, representing three major functional subsets. This study underscores the complexity of tumor–immune cross-talk, offering insights into how tumor heterogeneity shapes the immune landscape.
Significance: Tumor cells in different intratumoral neighborhoods display divergent patterns of ligands that regulate γδT-cell activation, highlighting multilevel regulation of antitumor immunity resulting from the heterogeneity of intercellular interactions in the tumor microenvironment.
Randomized Phase II Study of Durvalumab with or without Tremelimumab in Patients with Metastatic Castration-Resistant Prostate Cancer
Authors: Winquist Eric , Hotte Sebastien J. , Chi Kim , Sridhar Srikala , Ellard Susan , Ong Michael , Iqbal Nayyer , Salim Muhammad , Emmenegger Urban , Gingerich Joel R. , Lalani Aly-Khan , Major Pierre , Kollmannsberger Christian , Yip Steven , Hansen Aaron , Finch Daygen , Canil Christina , Hutchenreuther James , Vera-Badillo Francisco , Smoragiewicz Martin , Cabanero Michael , Tsao Ming-Sound , Ritch Elie , Wyatt Alexander W. , Seymour Lesley 
Published: November 2024

Abstract

Purpose:
PD-L1 is overexpressed by dendritic cells in patients with metastatic castration-resistant prostate cancer (mCRPC) progressing on androgen receptor pathway inhibitors. We tested whether checkpoint blockade could enhance antitumor activity in mCRPC.

Patients and Methods:
In a multicenter open-label noncomparative randomized phase II study, patients with mCRPC treated with ≤1 prior cytotoxic chemotherapy, with measurable disease and progression on abiraterone and/or enzalutamide, were randomized to durvalumab 1,500 mg intravenously every 4 weeks ±4 doses of tremelimumab 75 mg intravenously. The primary endpoint was objective response (OR) by iRECIST using a Simon two-stage design. Correlative testing included PD-L1/cluster designation 8 IHC on baseline tumor biopsies and deep targeted sequencing of plasma cell–free DNA.

Results:
Fifty-two patients were enrolled. Median age was 70 years (range, 50–83 years), and 52% had prior taxane therapy for mCRPC. In stage I, 13 patients were randomized to durvalumab with no OR observed. Durvalumab + tremelimumab advanced to stage II with 39 patients enrolled (receiving a median three cycles, range 1–53). Durvalumab + tremelimumab–related adverse events were mainly ≤ grade 2 but led to discontinuation in seven patients. There were seven ORs [19.4% (95% confidence interval: 8.2%–36.0%); intention to treat 17.9% (95% confidence interval: 7.5%–33.5%)]. Five responding tumors were PD-L1–positive and two exhibited DNA damage repair defects. Responses were observed without high tumor mutational burden or other genomic indices of immunotherapy sensitivity.

Conclusions:
Durvalumab + tremelimumab is active in mCRPC, but patient selection remains a challenge. Further studies to develop predictive biomarkers are warranted.
Re-Irradiation Plus Pembrolizumab: A Phase II Study for Patients with Recurrent Glioblastoma
Authors: Iwamoto Fabio M. , Tanguturi Shyam K. , Nayak Lakshmi , Wang Tony J. , Desai Arati , Lustig Robert A. , Bagley Stephen , Wong Eric T. , Hertan Lauren M. , McCluskey Christine , Hayden Julia , Muzikansky Alona , Nakhawa Shreya , Japo Julia , Bossi Connor C. , Meylan Maxime , Tian Ye , Barlow Graham L. , Speliakos Paul , Ayoub Georges , Meredith David M. , Ligon Keith L. , Haas-Kogan Daphne , Huang Kun , Wucherpfennig Kai W. , Wen Patrick Y. , Reardon David A. 
Published: November 2024

Abstract

Purpose:
Radiotherapy may enhance antitumor immune responses by several mechanisms, including induction of immunogenic cell death. We performed a phase 2 study of pembrolizumab with re-irradiation in patients with recurrent glioblastoma.

Patients and Methods:
Sixty patients with recurrent glioblastoma received pembrolizumab with re-irradiation alone (cohort A, bevacizumab-naïve; n = 30) or with bevacizumab continuation (cohort B, n = 30). Dual primary endpoints, including the overall response rate and overall survival (OS) at either 12 (OS-12; cohort A) or 6 months (OS-6; cohort B), were assessed per cohort relative to historic benchmarks. Paired paraffin-embedded formalin-fixed tumor samples were assessed for immunologic biomarkers by IHC using digital quantification and co-detection-by-indexing (CODEX).

Results:
Study therapy was well tolerated, with most toxicities being grade ≤3. For cohort B, the primary endpoint of OS-6 was achieved (57%); however, survival was not improved for cohort A patients. The overall response rate was 3.3% and 6.7% for cohorts A and B, respectively. CODEX analysis of paired tumor samples from five patients revealed an increase of activated T cells in the tumor microenvironment after study therapy.

Conclusions:
Compared with historic controls, re-irradiation plus pembrolizumab seemed to improve survival among bevacizumab-refractory patients but not among bevacizumab-naïve patients. CODEX revealed evidence of intratumoral infiltration of activated immune effector cells. A randomized, properly controlled trial of PD-1 blockade plus re-irradiation is warranted to further evaluate this regimen for bevacizumab-refractory patients, but alternative approaches are needed for bevacizumab-naïve patients.
Military Naming Practices of Palestinian Factions in Reactive Response to Israeli Incursions and Aggressions
Authors: Jabali Oqab , Dwikat Hanadi , Saeedi Munther 
Published: November 2024

Abstract
This article explores the military operation-naming practices of Palestinian factions in response to Israeli aggression, analyzing their strategies and their impact on the Israeli-Palestinian conflict dynamics. The research uses the War Normalizing Discourse (WND) theory as a framework and draws from Islamic tradition, official Hamas documentation, publicly disseminated materials, and insights from Arab intellectuals. The results show that the names chosen for military operations by Palestinian factions hold deep symbolic, cultural, and emotional significance, aiming to recruit fighters, gain public support, and maintain resilience. Understanding these naming practices provides valuable insights into the complex Israeli-Palestinian conflict and the intricate interplay between the nomenclature of battles conducted by Palestinian factions and Israel’s military operations.
The Problem of ‘Siloed Media Blocs’: How Modes of Communication Shape Our Organizing
Authors: Davidson Carl 
Published: November 2024

Abstract
Our mass media has taken us into a realm of political crisis, dividing our people in new ways, not simply in the old ways of class, race, and gender, or liberal and conservative. The multiple new ‘media silos’ – with conflicting ideas of ‘fake news,’ ‘alternate facts,’ and myriad conspiracies – also block any simple resolutions. In this article, we will try to dig deeper into this problem, and find what solutions we can.
Who’s Afraid of Jadidism?: Reckoning with the Legacy of a Cold War Paradigm
Authors: Ross Danielle 
Published: November 2024

Abstract
Since the 1990s, scholars in the fields of Central Asian, Volga-Ural, North and South Caucasian, and Crimean history have debated the role of Jadidism in the study of the history of Muslim societies under Russia imperial rule. The concept of Jadidism – variously described as a program for teaching literacy in Turkic languages, a set of educational reforms, and a movement advocating a broad range of cultural, social, and legal reforms designed to “modernize” Muslim communities – made its first appearances in Soviet historiography in the 1920s–1930s. In the 1960s, as the Cold War reached new heights, the Jadid paradigm made its way into English- and French-language historical studies, whence it became the primary lens through which Western audiences encountered and interpreted the histories of Muslims in late imperial Russia. The opening of archival and library collections following the collapse of the Soviet Union and the embrace of new theories and paradigms in Russian studies broke the hold of the Jadid paradigm over Western scholarship. At the same time, a series of heated disputes began over the legacy of the Jadid paradigm and how best to research the intellectual history of Russia’s Muslims in a post-Cold War context. In this essay, I will present a history of the rise and fall of the old Jadid paradigm in European and American scholarship. I will consider how the study of Central Asian intellectual history has evolved since the paradigm’s decline and what this evolution and the contributions to this journal issue suggest about how historians can continue to examine the nature, extent, and meaning of Muslim reform movements without reviving the old Jadid paradigm.
Who Were the Kazakh Jadids?
Authors: Frank Allen J. 
Published: November 2024

Abstract
Located between the Volga-Ural region and Central Asia, where jadidism has been scrupulously studied over the past half century, the Kazakh steppe was nevertheless also an arena for the development of jadid thought, here, as elsewhere, characterized by the coexistence of modernist and Islamic reformist ideas. During the later imperial period figures identifying themselves, or subsequently identified as jadids were numerous. Jadids were active in urban commercial settlements, including Troitsk, Petropavlovsk, and Omsk, as well as in nomadic encampments on the steppe, and included Tatars, Bashkirs, and Kazakhs. The Kazakh case brings into question problems in defining jadidism itself. This is because figures identified in Kazakh Soviet, post-Soviet and in Western historiography as “intellectuals” or supposedly secular reformers also fit the definition of jadidism.
Deliberate Practice with Motivational Interviewing: Basic Listening Skills for Undergraduates
Authors: Vega Angel L. , Olsen Joseph , Ogles Benjamin M. 
Published: November 2024

Background Training in professional psychology is moving beyond knowledge-based education and toward competency-based education. Similarly, experiential learning, focused more on skills than facts, is emphasized in undergraduate education. Few studies, however, have investigated the use of skill-based learning for clinically relevant skills in undergraduate psychology courses. Objective This study investigated deliberate practice as a skill-based method for training undergraduates to use basic Motivational Interviewing and reflective listening skills. Method In an upper-level undergraduate clinical psychology course, students were randomly assigned to an MI workshop that included deliberate practice to learn basic reflective listening skills or a waitlist control group. Results In both between (workshop versus waitlist) and within (pre versus post) group comparisons, students’ ability to use reflective listening improved as evaluated by raters, blind to condition, and in self-report measures of MI knowledge and skill. Conclusion Deliberate practice may be effectively incorporated into undergraduate courses to prepare novice helpers with basic listening skills. Teaching Implications Competency-based training in listening skills may help undergraduate students prepare for graduate school in the helping professions or any of multiple post-graduation professions not requiring professional training and licensure.
Risk factors for and short-term prognosis of intrauterine infection in preterm infants
Authors: Zhao Xuemei , Song Yue , Lu Liqun 
Published: November 2024

Objective To identify the risk factors for and short-term prognosis of intrauterine infection (IUI) in preterm infants. Methods We retrospectively collected clinical data regarding preterm infants (28+0–36+6 weeks of gestational age) with IUI from the neonatal intensive care unit of our hospital between June 2017 and June 2022. The pathologic characteristics of the infants were classified using the Redline criteria, and the resulting groups were compared with respect to their clinical characteristics, indicators of infection, complications, and mortality rates. Results Three hundred thirty (78.1%) of the 422 enrolled neonates showed signs of histologic IUI; 51.8% showed histologic chorioamnionitis alone, and 48.2% showed both histologic chorioamnionitis and funisitis. The independent risk factors identified for IUI were maternal prenatal invasive manipulation, premature rupture of membranes (>18 hours before labor), and prenatal C-reactive protein concentration. The infants with IUI showed higher incidences of respiratory distress syndrome, bronchopulmonary dysplasia, retinopathy of prematurity, and prolonged mechanical ventilation. Low gestational age and low birth weight of preterm infants were significantly associated with a higher incidence of histologic IUI, more severe inflammation, and a higher incidence of complications. Conclusions Histologic IUI is associated with high complication and mortality rates in preterm infants, as is an increasing severity of inflammation.
Mapping the Scientific Shreds on Barriers to SMEs’ Innovation
Authors: Gulia Disha , Arora Sapna , Rahul Kumar 
Published: November 2024

The present study aims to showcase the vital contributions to innovation barriers in the context of small and medium enterprises (SMEs) for 1975–2022. With the help of VOSviewer, this bibliometric analysis employs a quantitative method based on documents retrieved from SCOPUS database to assess historical patterns, results and the key elements affecting open innovation in SMEs. The results show an upward trend of research publications in the totality of the 222 documents contributed by 160 authors from 59 countries. The majority of research was conducted in developed countries. Findings also reveal the most cited research articles, keyword analysis, country collaboration and the number of documents published yearly. Language bias may occur as this bibliometric study only included literature written in a single language. Consequently, studies released in other languages may go unnoticed. This study is helpful for policymakers to provide a conducive environment for innovation among SMEs to keep economic growth on priority. This study offers the first comprehensive assessment of innovation barriers in a holistic manner. With the help of bibliometric analysis, the study assesses the intellectual framework of open innovation in SMEs.
Ultrasound Imaging for the Evaluation of Anterior Talofibular Ligament Remnants in 547 Ankles With Chronic Lateral Ankle Instability
Authors: Takao Masato , Iwashita Kosui , Miura Taihei , Sivasamy Parthiban , Inagawa Miyu , Watanabe Takashi , Jujo Yasuyuki 
Published: November 2024

Background: There are few reports on the intra- and interobserver agreement and parameters for the diagnostic accuracy of ultrasound (US) imaging for chronic lateral ankle instability (LAI). The purpose of this study was to investigate the reliability and validity of US imaging for identifying anterior talofibular ligament (ATFL) remnants in patients with LAI. Methods: A total of 547 ankles from 406 patients underwent surgery for LAI between 2019 and 2022. If ligament fibers remained in US images, they were evaluated as positive. If the ligament was not visualized, it was evaluated as negative. Two observers performed repeated measurements. Arthroscopic findings were considered the “gold standard” for validity and diagnostic test accuracy purposes. The intra- and interobserver agreements and parameters for diagnostic accuracy, including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of preoperative US imaging as intraoperative arthroscopic findings were used as reference standards. Results: The intraobserver agreement was substantial, with an agreement of 98.54% and a kappa coefficient of 0.76. The interobserver agreement was also substantial, with an agreement of 98.72% and a kappa coefficient of 0.75. The sensitivity, specificity, and accuracy of preoperative US imaging were 98.7%, 100%, and 98.7%, respectively. The PPV and NPV of US imaging were 100% and 61.1%, respectively. In the arthroscopic evaluation of the 7 cases in which US imaging showed false negative results, the ATFL ruptured at the fibular attachment and ran in contact with the talus. Conclusion: A US examination finding of an intact ATFL is highly likely to be correct. An US examination finding of a ruptured ATFL can be false and may require arthroscopic confirmation.