bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of a grapevine‐shoot waste extract on red wine aromatic properties
Authors: Ruiz‐Moreno María J , Raposo Rafaela , Puertas Belén , Cuevas Francisco J , Chinnici Fabio , Moreno‐Rojas José M , Cantos‐Villar Emma 
Published: April 2018

AbstractBACKGROUNDThe use of a grapevine‐shoot extract (VIN) is being studied as an alternative to sulfur dioxide (SO2). VIN stabilizes anthocyanins and preserves polyphenolic compounds, and thus improves chromatic wine properties. In this study, selected aroma compounds (esters, C13‐norisoprenoids, oxidation and vine‐shoot‐related compounds), sensory analysis and the olfactometric profile were determined in the wines treated with VIN at two concentrations.RESULTSTreatment with VIN hardly modified the content of esters and oxidation‐related compounds in the wines. However, the high β‐damascenone and isoeugenol contents and the increase in astringency at tasting in VIN wines were noteworthy, as were some odorant zones. All these were established as VIN markers after the chemometric data analysis.CONCLUSIONThese data revealed that only the lowest dose tested may be recommended as a suitable alternative to SO2. Although some aromatic properties of these wines may change, these changes are not considered to affect the quality of the wines negatively. These results are useful for wineries, which face having to discover the aroma‐related processes in the challenge of producing SO2‐free wines without detriment to their sensory properties. © 2018 Society of Chemical Industry
Ag(I)‐Catalyzed Chlorination of Linezolid during Water Treatment: Kinetics and Mechanism
Authors: Kulkarni Raviraj M. , Hanagadakar Manjunath S. , Malladi Ramesh S. , Shetti Nagaraj P. 
Published: April 2018

ABSTRACTThe kinetic and mechanistic study of Ag(I)‐catalyzed chlorination of linezolid (LNZ) by free available chlorine (FAC) was investigated at environmentally relevant pH 4.0–9.0. Apparent second‐order rate constants decreased with an increase in pH of the reaction mixture. The apparent second‐order rate constant for uncatalyzed reaction, e.g., k″app = 8.15 dm3 mol−1 s−1 at pH 4.0 and k″app. = 0.076 dm3 mol−1 s−1 at pH 9.0 and 25 ± 0.2°C and for Ag(I) catalyzed reaction total apparent second‐order rate constant, e.g., k″app = 51.50 dm3 mol−1 s−1 at pH 4.0 and k″app. = 1.03 dm3 mol−1 s−1 at pH 9.0 and 25 ± 0.2°C. The Ag(I) catalyst accelerates the reaction of LNZ with FAC by 10‐fold. A mechanism involving electrophilic halogenation has been proposed based on the kinetic data and LC/ESI/MS spectra. The influence of temperature on the rate of reaction was studied; the rate constants were found to increase with an increase in temperature. The thermodynamic activation parameters Ea, ΔH#, ΔS#, and ΔG# were evaluated for the reaction and discussed. The influence of catalyst, initially added product, dielectric constant, and ionic strength on the rate of reaction was also investigated. The monochlorinated substituted product along with degraded one was formed by the reaction of LNZ with FAC.
Conceptualization and model development of customer‐to‐customer encounter quality (CCEQ) in service settings
Authors: Kim Hyun Sik , Lee Jun Youb , La Suna , Choi Beomjoon 
Published: April 2018

AbstractDespite interests from many researchers, the conceptualization and measurement of customer‐to‐customer encounter quality (CCEQ) have mostly remained untapped. The present study aims to develop a conceptual framework to manage the impact of other customers on the focal customers’ service experience based on the perceived service quality framework. In Study 1, the authors employed critical incident technique to establish a multilayered factor structure of CCEQ consisted of three primary categories: customer‐to‐customer hedonic quality, customer‐to‐customer utilitarian quality, and customer‐to‐customer normative quality. In Study 2, the authors examined reliability and validity of the CCEQ model by using comprehensive confirmatory factor analyses and structural equation modeling. The results support the conceptualization of CCEQ proposed in Study 1. As an initial work as to the conceptualization and measurement of CCEQ model, this study provides theoretical and managerial insights into other customers’ influence on focal customers’ overall evaluation of service experiences.
Otolith-Chemistry-Based Discrimination of Wild- and Hatchery-Origin Steelhead across the Lake Michigan Basin
Authors: Watson Nicole M. , Prichard Carson G. , Jonas Jory L. , Student James J. , Pangle Kevin L. 
Published: April 2018

Abstract
Effective conservation and management of mixed-stock fisheries depends upon accurate stock identification of individual fish. We evaluated the utility of otolith chemical analysis as an approach to classify juvenile, premigratory steelhead Oncorhynchus mykiss collected in tributaries of Lake Michigan as either wild or hatchery origin. Two primary hypotheses proposed were that otolith chemistry can be used (1) to classify juvenile, hatchery-origin steelhead to the correct hatchery of origin and (2) to correctly classify stream-collected juvenile steelhead as wild or hatchery origin. Using laser-ablation inductively coupled plasma mass spectrometry, we analyzed the concentrations of seven elements (using 25Mg, 55Mn, 65Cu, 66Zn, 88Sr, 137Ba, 208Pb) in the otoliths of juvenile steelhead collected from five hatcheries and 25 streams in the Lake Michigan basin. When discriminating among hatcheries, only 4.41% of fish misclassified to an alternate hatchery when subjected to the best random forest classification algorithm that included all elements as predictor variables. Distinct chemical signatures between fish of wild and hatchery origin supported 100% classification accuracies of known-wild, age-0 steelhead as wild origin for 19 of the 25 streams sampled. Misclassification of wild, age-0, and hatchery-origin fish, which tended to occur for streams that were located in close proximity to the hatchery, never exceeded 3.4% for a given stream. Our findings demonstrate highly successful discrimination of hatchery-origin and wild juvenile steelhead across a broad geographic range. Applying the classification algorithms developed herein to unknown-origin steelhead provides the ability to infer survival of year-classes from specific hatcheries. Further, the ability to differentiate hatchery- and wild-origin fish will assist in stock assessment efforts allowing for increased effectiveness of conservation and management of the species.
Convergence estimates of nonrestarted and restarted block‐Lanczos methods
Authors: Zhou Ming 
Published: April 2018

SummaryThe block‐Lanczos method serves to compute a moderate number of eigenvalues and the corresponding invariant subspace of a symmetric matrix. In this paper, the convergence behavior of nonrestarted and restarted versions of the block‐Lanczos method is analyzed. For the nonrestarted version, we improve an estimate by Saad by means of a change of the auxiliary vector so that the new estimate is much more accurate in the case of clustered or multiple eigenvalues. For the restarted version, an estimate by Knyazev is generalized by extending our previous results on block steepest descent iterations and single‐vector restarted Krylov subspace iterations. The new estimates can also be reformulated and applied to invert‐block‐Lanczos methods for solving generalized matrix eigenvalue problems.
Prevalence of mindfulness literature and intervention in school psychology journals from 2006 to 2016
Authors: Bender Stacy L. , Roth Rachel , Zielenski Alicia , Longo Zachary , Chermak Ashley 
Published: April 2018

AbstractMindfulness has been gaining momentum in the field of school psychology, however compared to other applied psychology fields, less research on mindfulness interventions has been conducted. This study systematically reviewed mindfulness literature and empirical studies in nine school psychology journals from 2006–2016. The prevalence of mindfulness articles and research specifically focused on mindfulness intervention were examined. Additionally, the type of intervention implemented, tier of intervention, and targets of intervention were examined. Results indicated that .57% of articles during the ten‐year time frame were related to mindfulness (n = 17). Eight of the 17 articles investigated mindfulness interventions, with interventions ranging from informal practices (e.g., Mandala coloring) to specific intervention programs (e.g., Compassion and Attention in the Schools). Majority of interventions were implemented at the universal level for students. Future directions for mindfulness research and the importance of mindfulness in school psychology are discussed.
Controlled synthesis and evaluation of cyanate ester/epoxy copolymer system for high temperature molding compounds
Authors: Wu Fan , Tuan Chia‐Chi , Song Bo , Moon Kyoung‐Sik , Wong Ching‐Ping 
Published: April 2018

ABSTRACTEpoxy molding compounds (EMCs) have become an integral component for high power electronics to work under harsh environment nowadays. For high temperature operation, polymer networks with high glass transition temperature (Tg) are required to ensure device stability. In this work, high Tg polymers were designed via controlled incorporation of in situ formed and thermally stable triazine structures into epoxy matrix. Reactions involved in the copolymer system of cyanate ester and epoxy (CE/EP) were investigated. Increasing ratio of cyanate ester dramatically promoted Tg of the copolymer up to 275 °C with improved heat resistance. High temperature aging and moisture absorption tests revealed that hydrolysis of polycyanurate network and rearrangement of cyanurate occurred during aging, especially for copolymers with higher than 75% of cyanate ester. Based on thermal properties and aging performance, the composition of CE/EP system was optimized. The formulated bisphenol A cyanate ester and biphenyl epoxy copolymer system has great potential to be applied as high temperature encapsulation materials in electronic packaging. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 1337–1345
Mechanical properties of BiP protein determined by nano‐rheology
Authors: Casanova‐Morales Nathalie , Quiroga‐Roger Diego , Alfaro‐Valdés Hilda M. , Alavi Zahra , Lagos‐Espinoza Miguel I.A. , Zocchi Giovanni , Wilson Christian A.M. 
Published: April 2018

AbstractImmunoglobulin Binding Protein (BiP) is a chaperone and molecular motor belonging to the Hsp70 family, involved in the regulation of important biological processes such as synthesis, folding and translocation of proteins in the Endoplasmic Reticulum. BiP has two highly conserved domains: the N‐terminal Nucleotide‐Binding Domain (NBD), and the C‐terminal Substrate‐Binding Domain (SBD), connected by a hydrophobic linker. ATP binds and it is hydrolyzed to ADP in the NBD, and BiP's extended polypeptide substrates bind in the SBD. Like many molecular motors, BiP function depends on both structural and catalytic properties that may contribute to its performance. One novel approach to study the mechanical properties of BiP considers exploring the changes in the viscoelastic behavior upon ligand binding, using a technique called nano‐rheology. This technique is essentially a traditional rheology experiment, in which an oscillatory force is directly applied to the protein under study, and the resulting average deformation is measured. Our results show that the folded state of the protein behaves like a viscoelastic material, getting softer when it binds nucleotides‐ ATP, ADP, and AMP‐PNP‐, but stiffer when binding HTFPAVL peptide substrate. Also, we observed that peptide binding dramatically increases the affinity for ADP, decreasing it dissociation constant (KD) around 1000 times, demonstrating allosteric coupling between SBD and NBD domains.
Guanidine‐sensing riboswitches: How do they work and what do they regulate?
Authors: Battaglia Robert A. , Ke Ailong 
Published: April 2018

After remaining an orphan for over a decade, the ykkC riboswitch family (ykkC, mini‐ykkC, and ykkC‐III) was recently characterized as guanidine‐specific genetic regulatory elements (guanidine‐I, II, and III). They respond to increased levels of intracellular guanidine by turning on genes involved in guanidine export and breakdown. Their existence suggests that regulation of intracellular guanidine levels could be an important piece of bacterial physiology which was not appreciated previously. Structural biologists moved exceptionally fast to reveal the guanidine‐sensing mechanisms of these riboswitches at the atomic level. The crystal structures of all three guanidine family members have been determined. They appear to represent three independently evolved RNA sensors, with distinct tertiary folds but surprisingly similar guanidine‐binding cores. A few key questions remain to be addressed: It is not known which metabolic pathway(s) may lead to guanidine accumulation and the function of close relatives to the guanidine‐I riboswitch that do not respond to guanidine remains unclear. The continued characterization of these and other orphan cis‐regulatory elements represents an orthogonal approach to reveal new facets of bacterial physiology.This article is categorized under:

Regulatory RNAs/RNAi/Riboswitches > Riboswitches
RNA Structure and Dynamics > RNA Structure, Dynamics, and Chemistry
Work Engagement, Burnout and Personal Accomplishments Among Social Workers: A Comparison Between Those Working in Children and Adults’ Services in England
Authors: Hussein Shereen 
Published: April 2018

Abstract
Social workers (SWs) provide emotional and practical support to vulnerable service users who are likely to suffer from emotional trauma and mental health conditions. Stress and burnout levels are reported to be high among SWs, however, little is known about their relationships with different characteristics. The current article utilises unique and large dataset (n = 3786) on SWs working in adults and children’s services to examine factors associated with burnout. Employing job-demand/resources model and structural equations modelling, we highlight the varying significant impact of work-engagement, administrative support and work experience as moderating factors to burnout across adult and children service specialism in this sample.
Selectins modify dendritic cells during atherosclerosis
Authors: Ye Zhi‐Shuai , Huang Rong‐Chong 
Published: April 2018

AbstractDendritic cells (DCs) are professional antigen‐presenting cells (APC) that facilitate the development and progression of atherosclerosis. However, DCs also function as novel “switches” between immune activation and immune tolerance and represent a heterogeneous hematopoietic lineage, with cell subsets in different tissues that show a differential morphology, phenotype, and function. Regulatory DCs, depending on their immature state, can be induced by immunosuppressive modulation, which plays an important part in the maintenance of immunologic tolerance via suppression of the immune response. In this review, we describe the current understanding of the generation of regulatory DCs. The novel role of selectins in the modification of DCs in atherosclerosis is also discussed.
Staging of amyloid β, t‐tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses
Authors: Fletcher Evan , Filshtein Teresa Jenica , Harvey Danielle , Renaud Alice , Mungas Dan , DeCarli Charles ,   Alzheimer's Disease Neuroimaging Initiative
Published: April 2018

AbstractIntroductionCurrent models posit a sequence of amyloid β (Aβ), tau, atrophy, and cognitive change leading to Alzheimer's disease, but ambiguities remain. We examined these sequences via serial mediations.MethodsWe studied normal controls, early mild cognitive impairment, and late mild cognitive impairment individuals from the Alzheimer's Disease Neuroimaging Initiative 2 database for the mediation of baseline cerebrospinal fluid Aβ effects on 2‐year cognitive change via regional longitudinal atrophy rate (AR) alone or AR and tau.ResultsIn normal controls, Aβ correlated directly with regional ARs and memory loss, with no mediations. In early mild cognitive impairment, tau and lateral temporal ARs serially mediated the influence of Aβ on memory while Aβ affected memory via hippocampal AR. Late mild cognitive impairment consistently showed serial mediations of tau followed by atrophy. However, Aβ effects on memory also continued to be specifically mediated by medial temporal ARs without intermediate tau.DiscussionBiomarker sequences vary by region and disease state, suggesting the need to refine current cascade models.
Prevalence and Risk Factors for Musculoskeletal Pain in Keyboard Musicians: A Systematic Review
Authors: Amaral Corrêa Leticia , Teixeira dos Santos Luciano , Nogueira Paranhos Edmur Nelson , Minetti Albertini Alfredo Ignacio , do Carmo Silva Parreira Patrícia , Calazans Nogueira Leandro Alberto 
Published: April 2018

AbstractObjectiveTo identify the prevalence and risk factors for musculoskeletal pain in keyboard musicians.DesignSystematic reviewMethodsA systematic review was conducted according to the MOOSE recommendations and it was registered with the PROSPERO database under registration number CRD42016042913. We included observational studies through the electronic databases PubMed, Scopus, ScienceDirect, Web of Science, Répertoire International de Littérature Musicale (RILM), Retrospective Index to Music Periodicals (RIPM), Scielo, and Google Scholar, with combinations of the keywords pianists, keyboard players, musculoskeletal pain, muscular disease, tendinitis, tendinopathy, observational, case‐control, prevalence, and risk factors. Data from population, information about pain, and risk factors were extracted from studies that fulfilled the eligibility criteria. The methodological quality of the studies was classified through the Newcastle‐Ottawa Scale. The risk of bias and quality of evidence was assessed using the GRADE system.ResultsTwelve articles (case‐controls) were included for the qualitative synthesis. The quality of the studies was classified as fair (n = 6) and good (n = 6). Prevalence was observed between 25.8% and 77.0% of musculoskeletal pain among keyboard musicians, with a higher prevalence in wrists and hands (13.8%‐65.8%), neck (9.8%‐64.2%), and shoulders (9.8%‐59.8%). The only consistent risk factor found in the 4 studies was being female, with OR ranging from 1.05‐1.90. Age greater than 18 years; weekly training more than 20 hours; training for more than 60 minutes without a rest break; not having a habit of practicing sports; and playing despite the pain were also described as risks factors for musculoskeletal pain. It was not possible to perform the meta‐analysis due to the heterogeneity of the studies.ConclusionKeyboard musicians presented a high prevalence of musculoskeletal pain, especially in the upper extremity regions of the body. Female, ageing, playing behaviors, and sedentary lifestyle showed an increased likelihood to report musculoskeletal pain.Level of EvidenceII
The Possible Effect of Oxytocin in Postpartum Recovery From a Stroke: A Case Report
Authors: Seo Han Gil , Lee Hyun Haeng , Oh Byung‐Mo 
Published: April 2018

AbstractPregnancy is a risk factor for stroke in young women, but the effect of delivery on recovery and rehabilitation after stroke has not been elucidated in pregnant patients with stroke. This case report presents a pregnant patient with stroke who recovered successfully after cesarean delivery during rehabilitation. The possible effect of oxytocin is discussed as a factor promoting recovery from stroke.Level of EvidenceV
Teaching Open Science: Published Data and Digital Literacy in Archaeology Classrooms
Authors: Cook Katherine , Çakirlar Canan , Goddard Timothy , DeMuth Robert Carl , Wells Joshua 
Published: April 2018

ABSTRACTDigital literacy has been cited as one of the primary challenges to ensuring data reuse and increasing the value placed on open science. Incorporating published data into classrooms and training is at the core of tackling this issue. This article presents case studies in teaching with different published data platforms, in three different countries (the Netherlands, Canada, and the United States), to students at different levels and with differing skill levels. In outlining their approaches, successes, and failures in teaching with open data, it is argued that collaboration with data publishers is critical to improving data reuse and education. Moreover, increased opportunities for digital skills training and scaffolding across program curriculum are necessary for managing the learning curve and teaching students the values of open science.
Wild Pedagogies: Six Initial Touchstones for Early Childhood Environmental Educators
Authors: Jickling Bob , Blenkinsop Sean , Morse Marcus , Jensen Aage 
Published: April 2018

AbstractThis article is a small piece of a much larger and still evolving project. Herein we focus on six touchstones for wild pedagogies. The article begins with a short orientation to the larger ideas behind the project and then focuses on exploring six current touchstones with a view towards early childhood environmental educators. The six explored here are: (1) agency and the role of nature as co-teacher; (2) wildness and challenging ideas of control; (3) complexity, the unknown, and spontaneity; (4) locating the wild; (5) time and practice; and (6) cultural change.
Effectiveness of Probiotic for Primary Prevention of Clostridium difficile Infection: A Single-Center Before-and-After Quality Improvement Intervention at a Tertiary-Care Medical Center
Authors: Trick William E. , Sokalski Stephen J. , Johnson Stuart , Bunnell Kristen L. , Levato Joseph , Ray Michael J. , Weinstein Robert A. 
Published: April 2018

OBJECTIVETo evaluate probiotics for the primary prevention of Clostridium difficile infection (CDI) among hospital inpatients.DESIGNA before-and-after quality improvement intervention comparing 12-month baseline and intervention periods.SETTINGA 694-bed teaching hospital.INTERVENTIONWe administered a multispecies probiotic comprising L. acidophilus (CL1285), L. casei (LBC80R), and L. rhamnosus (CLR2) to eligible antibiotic recipients within 12 hours of initial antibiotic receipt through 5 days after final dose. We excluded (1) all patients on neonatal, pediatric and oncology wards; (2) all individuals receiving perioperative prophylactic antibiotic recipients; (3) all those restricted from oral intake; and (4) those with pancreatitis, leukopenia, or posttransplant. We defined CDI by symptoms plus C. difficile toxin detection by polymerase chain reaction. Our primary outcome was hospital-onset CDI incidence on eligible hospital units, analyzed using segmented regression.RESULTSThe study included 251 CDI episodes among 360,016 patient days during the baseline and intervention periods, and the incidence rate was 7.0 per 10,000 patient days. The incidence rate was similar during baseline and intervention periods (6.9 vs 7.0 per 10,000 patient days; P=.95). However, compared to the first 6 months of the intervention, we detected a significant decrease in CDI during the final 6 months (incidence rate ratio, 0.6; 95% confidence interval, 0.4–0.9; P=.009). Testing intensity remained stable between the baseline and intervention periods: 19% versus 20% of stools tested were C. difficile positive by PCR, respectively. From medical record reviews, only 26% of eligible patients received a probiotic per the protocol.CONCLUSIONSDespite poor adherence to the protocol, there was a reduction in the incidence of CDI during the intervention, which was delayed ~6 months after introducing probiotic for primary prevention.Infect Control Hosp Epidemiol 2018;765–770