bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifikasi dan Prevalensi Cacing Endoparasit pada Saluran Pencernaan Kakap Merah (Lutjanus argentimaculatus) di Keramba Jaring Apung Balai Besar Perikanan Budidaya Laut, Lampung <br><i>[Identification And Prevalence of Endoparasite Worms in The Gastrointestinal Tract of Red Snapper (Lutjanus argentimaculatus) In Floating Net The Centre Of Mariculture, Lampung]<i>
Authors: Puspitarini Diah Ayu , Subekti Sri , Kismiyati Kismiyati 
Published: November 2018

AbstrakPenelitian ini bertujuan untuk mengetahui jenis dan tingkat prevalensi cacing endoparasit pada saluran pencernaan kakap merah (Lutjanus argentimaculatus) di Keramba Jaring Apung Balai Besar Perikanan Budidaya Laut Lampung. Metode yang digunakan dalam penelitian ini adalah metode survey. Pengambilan sampel sebanyak 30 ekor ikan yang berukuran 20-35 cm menggunakan metode purposive sampling. Organ yang diamati lambung dan usus, kemudian dilakukan identifikasi dan penghitungan prevalensi. Hasil dari penelitian ini menunjukkan jenis cacing endoparasit yang menginfeksi saluran pencernaan kakap merah (Lutjanus argentimaculatus) di Keramba Jaring Apung Balai Besar Perikanan Budidaya Laut Lampung adalah larva stadium tiga Anisakis physeteris (Anisakis tipe II) dan Cucullanus heterochrous. Prevalensi kakap merah yang terinfeksi endoparasit adalah 10%, terdiri dari Anisakis physeteris (Anisakis tipe II) sebesar 7% dan Cucullanus heterochrous sebesar 3%. AbstractThe purpose of the research is to know kinds and prevalence of endoparasites worm gastrointestinal red snapper (Lutjanus argentimaculatus) in floating net cages the Centre of Mariculture Lampung. The metode of the research is survey method. The sample that used is 30 fishes that size 20-35 cm used purposive sampling method. The organ that getting examination is intestine and stomach, after that do identification and counting of prevalence. The result showed kinds of endoparasite worms that infected is stage three larvae of Anisakis physeteris (Anisakis type II) and Cucullanus heterochrous. The prevalence of endoparasites in red snapper is 10% that consist from on Anisakis physeteris (Anisakis type II) 7% and Cucullanus heterochrous 3%.
Tuberculosis Incidence Among Populations at High Risk in California, Florida, New York, and Texas, 2011–2015
Authors: Cherng Sarah T. , Shrestha Sourya , Reynolds Sue , Hill Andrew N. , Marks Suzanne M. , Kelly Jane , Dowdy David W. 
Published: November 2018

Objectives. To illustrate the magnitude of between-state heterogeneities in tuberculosis (TB) incidence among US populations at high risk for TB that may help guide state-specific strategies for TB elimination. Methods. We used data from the National Tuberculosis Surveillance System and other public sources from 2011 to 2015 to calculate TB incidence in every US state among people who were non–US-born, had diabetes, or were HIV-positive, homeless, or incarcerated. We then estimated the proportion of TB cases that reflected the difference between each state’s reported risk factor–specific TB incidence and the lowest incidence achieved among 4 states (California, Florida, New York, Texas). We reported these differences for the 4 states and also calculated and aggregated across all 50 states to quantify the total percentage of TB cases nationally that reflected between-state differences in risk factor–specific TB incidence. Results. On average, 24% of recent TB incidence among high-risk US populations reflected heterogeneity at the state level. The populations that accounted for the greatest percentage of heterogeneity-reflective cases were non–US-born individuals (51%) and patients with diabetes (24%). Conclusions. State-level differences in TB incidence among key populations provide clues for targeting state-level interventions.
Disparities in Hepatitis B Virus Infection and Immunity Among New York City Asian American Patients, 1997 to 2017
Authors: Tang Amy S. , Lyu Janice , Wang Su , He Qingqing , Pong Perry , Harris Aaron M. 
Published: November 2018

Objectives. To measure disparities in hepatitis B virus (HBV) infection and immunity among a high-risk patient population at a community health center in New York City. Methods. We performed a retrospective chart review of 25 565 adults with HBV surface antigen, surface antibody, and total core antibody tests from 1997 to 2017. We categorized HBV test results by infection and immunity status and analyzed by demographic characteristics with χ2 and logistic regression analysis. Results. Of 25 565 adults, 13.4% were currently infected, 52.1% were ever infected, 33.4% were immune from vaccination, and 14.5% were susceptible. Significant factors associated with ever infection were age, male sex, being China-born, limited English proficiency, having Medicaid or no insurance, and family history of HBV (P < .01). Conclusions. Our study demonstrated a high burden of HBV infection among foreign-born Asian Americans seeking care at a community health center. Public Health Implications. It is important to test patients at high risk for HBV infection with all 3 tests to identify those with current infection, risk for reactivation, or need for vaccination, and to assess the effectiveness of public health interventions.
Using Sexual Orientation and Gender Identity to Monitor Disparities in HIV, Sexually Transmitted Infections, and Viral Hepatitis
Authors: Shover Chelsea L. , DeVost Michelle A. , Beymer Matthew R. , Gorbach Pamina M. , Flynn Risa P. , Bolan Robert K. 
Published: November 2018

Objectives. To quantify sexual orientation and gender identity (SOGI) disparities in incidence of HIV, other sexually transmitted infections (STIs), and viral hepatitis. Methods. We performed a records-based study of 19 933 patients visiting a federally qualified health center in Los Angeles, California, between November 2016 and October 2017 that examined HIV, STIs, and viral hepatitis incidence proportions. We created multivariable logistic regression models to examine the association between incidence proportions and SOGI among people living with HIV and HIV-negative patients. Results. Among those who were HIV-negative at baseline (n = 16 757), 29% tested positive for any STI during the study period, compared with 38% of people living with HIV. Stratified by birth sex, STI positivity was 32% among men and 11% among women. By SOGI, STI positivity was 35% among gay and bisexual cisgender men, 15% among heterosexual cisgender men, 11% among cisgender women, 25% among transgender women, 13% among gay and bisexual transgender men, 3% among heterosexual transgender men, and 26% among nonbinary people. Conclusions. Stratifying by SOGI highlighted disparities that are obscured when stratifying by birth sex. Public Health Implications. To monitor and reduce disparities, health jurisdictions should include SOGI data with infectious disease reporting.
Intravitreal Dexamethasone Implants versus Intravitreal Anti-VEGF Treatment in Treating Patients with Retinal Vein Occlusion: A Meta-analysis
Authors: Shi Qian , Gao Lixiong , Zhou Lijun , Tian Chunyu , Li Na , Shao Weiyang , Peng Xiujun 
Published: November 2018

Abstract
Background: Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implants and anti-vascular endothelial growth factor (VEGF). The goal of this study is to compare the effectiveness and safety of dexamethasone implants and anti-VEGF treatment for RVO.
Methods: The PubMed, Embase, and Cochrane Library databases were searched for studies comparing dexamethasone implants with anti-VEGF in patients with RVO. Best-corrected visual acuity (BCVA), central subfield thickness (CST), intraocular pressure changes, conjunctival haemorrhage, reduced VA, and macular oedema were extracted from the final included studies. RevMan 5.3 was used to conduct the quantitative analysis and bias assessment.
Results: Four articles assessing 969 eyes were included. The anti-VEGF treatment showed better BCVA improvement (mean difference [MD] = -10.59, P < 0.00001) and more CST decrease (MD = -86.71 μm, P = 0.02) than the dexamethasone implants. However, the dexamethasone implants required fewer injections. As for adverse effects, the dexamethasone implants showed significantly higher intraocular pressure (IOP) and more cataracts than the anti-VEGF treatment. No significant differences were found in conjunctival haemorrhage, reduced VA, and macular oedema.
Conclusions: Anti-VEGF treatment showed better functional and anatomical improvement with less risk of IOP elevation and cataract formation compared to dexamethasone implants. Thus, anti-VEGF treatment is the first choice for treating RVO patients.

Keywords: dexamethasone intravitreal implant, anti-VEGF treatment, retinal vein occlusion, meta-analysis
THE VALUE OF PROGNOSTIC FACTORS FOR GLIOBLASTOMA TREATED WITH CONCURRENT THERMOCHEMORADIOTHERAPY
Authors: Ryabova A. I. , Novikov V. A. , Gribova O. V. , Startseva Zh. A. , Grigoriev E. G. , Glushchenko S. A. , Ponomaryova A. A. , Sirkashev V. A. 
Published: November 2018

The treatment of patients with glioblastoma continues to be one of the greatest challenges. Glioblastoma is the most aggressive malignant primary brain tumor and is the most lethal among all cancers. Despite advances in the standard treatment, the prognosis for patients with glioblastoma remains poor, therefore, the development of novel treatment strategies is required.Material and methods.Our study included 30 patients with newly diagnosed glioblastoma, who underwent concurrent chemoradiotherapy and local hyperthermia.Results.The median disease-free and overall survival rates were 9.6 months and 23 months, respectively. The analysis of clinical, molecular-genetic and prognostic factors related to treatment modality showed statistically significant differences in survival between patient groups representing different times for starting adjuvant therapy after surgery. The median disease-free survival was significantly higher in patients who received chemoradiotherapy with local hyperthermia within 6 weeks after surgery than in patients who started adjuvant treatment earlier. The overall survival rate was statistically higher in patients receiving a special treatment for tumor recurrence compared to that in patients receiving symptomatic therapy. The evaluation of molecular-genetic prognostic factors showed no statistically significant differences in survival among patients with methylated and nonmethylated MGMT promoter. The presence of IDH1 mutations was identified in only one case. Evaluation of prognostic factors does not allow identification of clinical and molecular biological factors that group patients with hypersensitivity to the proposed treatment regimen. However, high rates of overall and disease-free survival, even in patients with non-methylated MGMT, allow us to recommend this treatment modality for patients with newly diagnosed glioblastoma.
Carcinoembryonic antigen BEFORE AND AFTER neoadjuvant chemoradiotherapy IN PREDICTION OF pathological complete response in patients with locally advanced rectal cancer
Authors: Severskaya N. V. , Erygin D. V. , Aleksandrov Yu. V. , Minaeva N. G. , Dvinskikh N. Yu. , Novikov N. Yu. 
Published: November 2018

Carcinoembryonic antigen (CEA) is widely used to evaluate the effectiveness of treatment in patients with rectal cancer.The aim of the studywas to investigate whether the CEA levels measured before and after neoadjuvant chemoradiotherapy (nCRT) can be used to predict pathological complete response (pCR) in patients with locally advanced rectal cancer.Material and methods.179 patients with locally advanced rectal cancer were treated with nCRT followed by surgical treatment. The serum CEA level was measured before and 610 weeks after the completion of nCRT. Preand post nCRT CEA levels were compared with pCR. The factors associated with pCR were studied.Results.pCR after nCRT was achieved in 12 % (22/179) patients. The incidence of pCR was higher in patients with normal (<5 ng/mL) pre-treatment CEA level (20 %vs8 %, p=0.019). In patients with the elevated pre-treatment CEA level (> 5 ng/mL), there were no significant differences in the incidence of pCR between cases with normalization and without normalization of CEA level after treatment (p=0.08). The maximum likelihood of pCR determined by the ROC curve was <2.8 ng/mL with pre-treatment CEA (31 %) and <1.8 ng/mL with post-treatment CEA (23 %). Well differentiated tumors (G1) had higher likelihood of pCR (46%) in patients with low pre-treatment CEA (<2.8 ng/mL).Conclusion.Low CEA before and after nCRT is a predictor of pCR. Well differentiated tumors increase the probability of pCR after nCRT.
What We Talk about When We Talk about Soil Health
Authors: Stewart Ryan D. , Jian Jinshi , Gyawali Ayush J. , Thomason Wade E. , Badgley Brian D. , Reiter Mark S. , Strickland Michael S. 
Published: November 2018

Core Ideas
Despite nationwide emphasis on soil health in the USA, current measurements lack consistency.
A meta‐analysis showed 8 of 42 soil health indicators reported >20% of time.
Only 13 indicators showed short‐term (1–3 yr timescale) responses to cover cropping.
Wide variation in soil sampling protocols suggests standardization is needed.
Translating soil health research across systems requires a common framework.
Despite a nationwide emphasis on improving soil health in the United States, current measurement protocols have little consistency. To survey assessment practices, we conducted a meta‐analysis of cover crop (n = 86) and no‐tillage (n = 106) studies and compiled reported indicators, cropping systems, and soil sampling protocols from each. We then analyzed which indicators significantly responded to cover crop usage after 1 yr and 2 to 3 yr. Our results showed that out of 42 indicators, only 8 were reported in >20% of studies. Thirteen indicators showed >10% relative response after 1 to 3 yr; the remainder lacked either sufficient observations or consistent results. Looking forward, we propose that emphasis should be placed on (i) pursuing dynamic indicators (e.g., aggregate stability), (ii) standardizing sampling protocols, and (iii) developing a common framework for information sharing. These efforts will generate new insight into soil health across systems, ultimately ensuring that soil health science is useful to producers and regulators.
Genetic Diversity of Sour Passion Fruit Revealed by Predicted Genetic Values
Authors: Rosado Renato D. S. , Rosado Luciana D. S. , Borges Leandro L. , Bruckner Claúdio H. , Cruz Cosme D. , dos Santos Carlos E. M. 
Published: November 2018

Core Ideas
The sporophytic homomorphic self‐incompatibility system advanced the greatest diversity within populations.
The phenotypic correlation network facilitates rapid observation of the relationships among groups of variables related to vegetative vigor, incidence of leaf diseases, and physicochemical properties of passion fruit.
The correlation networks associated with the relative contribution of the variable can help in the selection of important variables.
Sour passion fruit (Passiflora edulis Sims) is a highly suitable crop for small farmers because of its high market value and short time to maturity. However, passion fruit breeding programs need to provide cultivars to producers with quality, disease resistance, and production improvements. The objective of this study was to assess the genetic diversity among and within improved populations of sour passion fruit (SPF) using predicted genetic values, select the most divergent accessions, and evaluate the relationships among groups of traits of vegetative vigor, incidence of leaf diseases, and physicochemical properties of fruits. Twenty‐three genotypes were selected and divided into five populations with variable numbers of accessions. Phenotypic data were transformed into genotypic values using mixed model restricted maximum likelihood‐best linear unbiased prediction. We tested the hypothesis that there is differentiation among populations and between their components and the accessions. Graphic dispersion of the genotypes around the centroids of five populations was performed. The Tocher method was used to group the accessions. The relative importance of the variables and correlation networks was evaluated. Populations showed genetic variability; the hybrid combinations involving the population I accessions 1 (B1 29 PL1), 2 (B1 41 PL3), 4 (B2 9 PL 3), 5 (B2 37 PL3), 10 (G1 B1 9), and 19 (BRS GA1) can be exploited in breeding programs to improve the quality of SPF. The correlation network facilitates the observation of the relationships among groups of traits and helps in the selection of variables when associated with the relative contribution.
Impact of Melaleuca quinquenervia Biochar on Phaseolus vulgaris Growth, Soil Nutrients, and Microbial Gas Flux
Authors: Velez Thelma I. , Moonilall Nall I. , Reed Stewart , Jayachandran Krishnaswamy , Scinto Leonard J. 
Published: November 2018

Biochar has been heralded for improving soil quality, sequestering C, and converting organic residues into value‐added amendments. Biochar research in agricultural settings has been primarily conducted on acidic soils, with few studies evaluating biochar effects on alkaline soils. Given the rise of small‐scale, sustainable farmers experimenting with biochar in South Florida's alkaline, carbonaceous soil, this study sought to assess biochar use in South Florida using an invasive plant species as a feedstock. Melaleuca quinquenervia (Cav.) S.T. Blake biomass was converted into biochar to measure how application at two rates, 2 and 5% (w/w), affects plant growth, soil macro‐ and micronutrients, and microbial gas flux (CO2) in a potted greenhouse experiment using Phaseolus vulgaris L. Plant growth was inhibited with biochar addition at the 2 and 5% rates. Dry shoot, pod weight, and pod length decreased significantly between treatments (P < 0.001). Significant reductions in plant‐available P, Ca, Mg, Cu, and Zn were observed in the 5% biochar soil postharvest (P < 0.05). Compared with the control, addition of biochar at 2 and 5% rates significantly reduced CO2 flux during the growing season, but not at harvest (P < 0.01). Our results indicate that those considering biochar application in South Florida's alkaline soil should be cautious in selecting feedstock and temperature for biochar production. Biochar can be produced at lower temperatures to decrease pH, but the concomitant increase in volatile matter (VM) is of concern. Although CO2 flux may have decreased, the deleterious impacts of M. quinquenervia biochar (pH = 8.12, VM = 26.5%) on P. vulgaris production should not be dismissed.Core Ideas
South Florida invasive Melaleuca quinquenervia was used to make biochar.
Increasing rates of M. quinquenervia biochar reduced bean growth in calcareous soil.
A 5% (w/w) rate of M. quinquenervia biochar reduced available nutrients in soil.
Melaleuca quinquenervia biochar addition reduced soil respiration compared with the control.
OMERE: A Long‐Term Observatory of Soil and Water Resources, in Interaction with Agricultural and Land Management in Mediterranean Hilly Catchments
Authors: Molénat J. , Raclot D. , Zitouna R. , Andrieux P. , Coulouma G. , Feurer D. , Grunberger O. , Lamachère J.M. , Bailly J.S. , Belotti J.L. , Ben Azzez K. , Ben Mechlia N. , Ben Younès Louati M. , Biarnès A. , Blanca Y. , Carrière D. , Chaabane H. , Dagès C. , Debabria A. , Dubreuil A. , Fabre J.C. , Fages D. , Floure C. , Garnier F. , Geniez C. , Gomez C. , Hamdi R. , Huttel O. , Jacob F. , Jenhaoui Z. , Lagacherie P. , Le Bissonnais Y. , Louati R. , Louchart X. , Mekki I. , Moussa R. , Negro S. , Pépin Y. , Prévot L. , Samouelian A. , Seidel J.L. , Trotoux G. , Troiano S. , Vinatier F. , Zante P. , Zrelli J. , Albergel J. , Voltz M. 
Published: November 2018

Core Ideas
OMERE is a Mediterranean observatory of two farmed catchments in Tunisia and France.
Water, contaminant, and erosion fluxes are monitored from plot to catchment scales.
Soils and land use in relation with agriculture are surveyed.
Scientific results concern elementary processes and integrated catchment functioning.
Models were conceived for evaluation of land use and agricultural management scenarios.
To account for the diversity of agricultural and ecosystem situations in hilly Mediterranean areas, the agro‐hydrological observatory OMERE (Observatoire Méditerranéen de l'Environnement Rural et de l'Eau) monitors two farmed catchments—one in northern Tunisia and the other in southern France. Mediterranean regions are typified by a highly variable climate, with an alternation of long droughts and intense storms, and by a strong heterogeneity of soil properties, due to a combination of climate, relief, parent materials, sparse vegetation, intense land use, man‐made infrastructure (ditches, terraces, etc.), and agricultural activities. In this context, OMERE aims to document the impacts of agricultural and land management on mass fluxes in Mediterranean farmed headwater catchments. The observation strategy is motivated by monitoring water, sediment, and contaminant fluxes and hydrologic and climatic variables at different spatial scales from cultivated plots and landscape elements to the catchment scale. These measurements have been performed at a fine time resolution over a long‐term scale and by surveying land use, agricultural practices, and soil surface characteristics. The long‐term observation strategy intends to support integrative multidisciplinary research for elucidating the conditions that improve soil and water management and delivery of ecosystem services in a Mediterranean rainfed cultivated context. The observatory has led to scientific insights regarding three scientific objectives: (i) to better understand the fluxes of water, erosion, and contaminants, especially pesticides, and of their natural and anthropogenic drivers on short‐ and long‐term scales; (ii) to analyze the aggregate effects of farming and land management on mass fluxes across scales, from plot to catchment or landscape scales; and (iii) to derive new scenarios for sustainable agricultural management and improved delivery of ecosystem services.
Computational Advances in the Label-free Quantification of Cancer Proteomics Data
Authors: Tang Jing , Zhang Yang , Fu Jianbo , Wang Yunxia , Li Yi , Yang Qingxia , Yao Lixia , Xue Weiwei , Zhu Feng 
Published: November 2018

Background:
Due to its ability to provide quantitative and dynamic information on tumor genesis and
development by directly profiling protein expression, the proteomics has become intensely popular for characterizing
the functional proteins driving the transformation of malignancy, tracing the large-scale protein alterations
induced by anticancer drug, and discovering the innovative targets and first-in-class drugs for oncologic disorders.

Objective:
To quantify cancer proteomics data, the label-free quantification (LFQ) is frequently employed. However,
low precision, poor reproducibility and inaccuracy of the LFQ of proteomics data have been recognized as
the key “technical challenge” in the discovery of anticancer targets and drugs. In this paper, the recent advances
and development in the computational perspective of LFQ in cancer proteomics were therefore systematically
reviewed and analyzed.

Methods:
PubMed and Web of Science database were searched for label-free quantification approaches, cancer
proteomics and computational advances.

Results:
First, a variety of popular acquisition techniques and state-of-the-art quantification tools are systematically
discussed and critically assessed. Then, many processing approaches including transformation, normalization,
filtering and imputation are subsequently discussed, and their impacts on improving LFQ performance of
cancer proteomics are evaluated. Finally, the future direction for enhancing the computation-based quantification
technique for cancer proteomics are also proposed.

Conclusion:
There is a dramatic increase in LFQ approaches in recent year, which significantly enhance the
diversity of the possible quantification strategies for studying cancer proteomics.