bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural and optical properties of VO2+doped methacrylic acid ethylacrylate (MAA:EA) copolymer films
Authors: Kumar Y. Madhava , Bhyagyasree K. , Gopal N.O. , Ramu Ch. 
Published: April 2018

AbstractPure and VO2+doped methacrylic acid ethylacrylate (MAA:EA) copolymer films were prepared by using a solution casting method. Various techniques including X-ray diffraction, Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, scanning electron microscopy and electron paramagnetic resonance were employed for characterization of the samples. XRD patterns showed some degree of crystallinity of the doped polymer films due to interaction of the MAA:EA copolymer with VO2+. FT-IR spectral studies of pure and VO2+doped MAA:EA copolymer films displayed significant structural changes within the doped copolymer film indicating the complexation. The optical absorbance of the pure and VO2+doped films were measured in the 200 nm to 800 nm wavelength range. The values of the absorption edge and indirect band gaps were calculated. The optical band gap decreased with the increase of mol% of VO2+. From the EPR spectra, the spin- Hamiltonian parameters (g and A) were evaluated. The values of the spin-Hamiltonian parameters confirmed that the vanadyl ions were present in MAA:EA copolymer films as VO2+molecular ions in an octahedral site with a tetragonal compression (C4v). The morphology of the copolymer samples was examined by scanning electron microscopy. The enhanced crystalline nature of the doped copolymer was identified from SEM analysis.
Application of argon plasma sheet in the etching process of calcium carbonate crystals for AFM tests
Authors: Moczała Magdalena , Karpińska Miriam , Poznar Monika , Dobryszycki Piotr , Sikora Andrzej 
Published: April 2018

Abstract
This paper presents utilization of argon plasma for gradual etching of calcium carbonate crystals. The plasma treatment has been chosen as it appears to be the technique that enables removal of following material layers, thus, the access to the inside of crystals is possible. Examples of investigations of the morphology and mechanical properties of surfaces of calcium carbonate crystals are presented. The impact of plasma treatment has been verified in terms of roughness and volume changes investigated using atomic force microscopy technique in a multi-step experiment. Therefore, we were able to observe the crystal degradation process, revealing the spatial inhomogeneity of the calcium carbonate crystals resulting from their core-shell structure.
Optical characterizations of two-dimensional materials using nonlinear optical microscopies of CARS, TPEF, and SHG
Authors: Li Rui , Zhang Yajun , Xu Xuefeng , Zhou Yi , Chen Maodu , Sun Mengtao 
Published: April 2018

AbstractIn this paper, we employ the nonlinear optical microscopies of coherent anti-Stokes Raman scattering spectroscopy, two-photon excitation fluorescence, and second harmonic generation to characterize the properties of two-dimensional (2D) materials. With these nonlinear optical microscopy methods, we can not only clearly observe the surface topography of 2D materials but also reveal the quality of 2D materials. These nonlinear optical microscopies offer great potential for characterization of the properties of 2D materials.
Channel Simulation in Quantum Metrology
Authors: Laurenza Riccardo , Lupo Cosmo , Spedalieri Gaetana , Braunstein Samuel L. , Pirandola Stefano 
Published: April 2018

Abstract
In this review we discuss how channel simulation can be used to simplify the most general protocols of quantum parameter estimation, where unlimited entanglement and adaptive joint operations may be employed. Whenever the unknown parameter encoded in a quantum channel is completely transferred in an environmental program state simulating the channel, the optimal adaptive estimation cannot beat the standard quantum limit. In this setting, we elucidate the crucial role of quantum teleportation as a primitive operation which allows one to completely reduce adaptive protocols over suitable teleportation-covariant channels and derive matching upper and lower bounds for parameter estimation. For these channels,wemay express the quantum Cramér Rao bound directly in terms of their Choi matrices. Our review considers both discrete- and continuous-variable systems, also presenting some new results for bosonic Gaussian channels using an alternative sub-optimal simulation. It is an open problem to design simulations for quantum channels that achieve the Heisenberg limit.
Structure, mechanism, and performance evaluation of natural gas hydrate kinetic inhibitors
Authors: Shahnazar Sheida , Bagheri Samira , TermehYousefi Amin , Mehrmashhadi Javad , Abd Karim Mohd Sayuti , Kadri Nahrizul Adib 
Published: April 2018

Abstract
Ice-like crystal compounds, which are formed in low-temperature and high-pressure thermodynamic conditions and composed of a combination of water molecules and guest gas molecules, are called gas hydrates. Since its discovery and recognition as the responsible component for blockage of oil and gas transformation line, hydrate has been under extensive review by scientists. In particular, the inhibition techniques of hydrate crystals have been updated in order to reach the more economically and practically feasible methods. So far, kinetic hydrate inhibition has been considered as one of the most effective techniques over the past decade. This review is intended to classify the recent studies regarding kinetic hydrate inhibitors, their structure, mechanism, and techniques for their performance evaluation. In addition, this communication further analyzes the areas that are more in demand to be considered in future research.
Comparison of Linear Temperature Corrections and Activation Energy Temperature Corrections for Electrical Resistivity Measurements of Concrete
Authors: Coyle Alex T. , Spragg Robert P. , Suraneni Prannoy , Amirkhanian Armen N. , Weiss William J. 
Published: April 2018

Abstract
Electrical resistivity measurements are increasingly being used as measurements for concrete acceptance in practice. It has been shown that these measurements are sensitive to temperature. This paper examines the influence of temperature on electrical resistivity measurements in concrete. Two temperature correction approaches that are commonly used by researchers and practitioners were evaluated: a linear temperature correction approach (α) and an activation energy–based temperature correction approach (Ea-cond). These approaches were compared with each other and their predictive capabilities were assessed using measured data from various concrete mixtures. It was found that for cases of low temperature sensitivity (low values of α or Ea-cond), the predictions obtained with α and with Ea-cond were similar. However, the Ea-cond approach was found to provide more accurate corrections (lower error) than corrections using α for measurements conducted at lower temperatures and for systems with higher temperature sensitivities (high values of α or Ea-cond). For saturated concrete specimens, both the linear (α) and activation energy (Ea-cond) approaches are acceptable, whereas the use of the Ea-cond approach provides better predictive capabilities in sealed concrete specimens, especially at low temperatures. The average values for Ea-cond were found to be 29.8 kJ/mol for sealed specimens and 15.8 kJ/mol for saturated specimens, and corresponding average values of α are 3.25 %/°C and 2.00 %/°C, respectively. The values for Ea-cond for saturated specimens are closer to what is expected of a pore solution on its own.
Primary high-grade calcitonin-negative neuroendocrine carcinoma of the thyroid: a very rare cancer
Authors: Chorny Joseph A , Orrego John J , Cameselle-Teijeiro José Manuel 
Published: April 2018

Summary
Most medullary thyroid carcinomas (MTCs) are low grade and produce calcitonin. There are some calcitonin-negative MTCs that produce only calcitonin gene-related peptide (CGRP). Rarely, MTCs are negative for calcitonin and CGRP peptides, but contain their corresponding mRNAs. Primary thyroid neuroendocrine neoplasms other than MTCs are extremely rare. We describe a primary high-grade neuroendocrine carcinoma that was negative for CGRP and calcitonin at both the protein and mRNA levels. A 42-year-old woman presented with a rapidly enlarging thyroid mass replacing most of the left lobe and isthmus. A computed tomography-guided core-needle biopsy was performed. The tumor was composed of sheets of small-to-medium sized epithelial cells. The cells were immunoreactive for pancytokeratin, synaptophysin, CD56 and thyroid transcription factor-1, but negative for CK7, CK20, CD45, CD99, ERG, chromogranin A, thyroglobulin, calcitonin, CGRP and carcinoembryonic antigen. The Ki-67 proliferation index was ~90%. In situ hybridization was negative for calcitonin mRNA. The patient was initially diagnosed as having a small cell carcinoma. She was treated with cisplatin and etoposide (VP16), followed by radiation therapy. Given the excellent clinical course, the tumor was reviewed and reclassified as a high-grade neuroendocrine carcinoma (non-small-cell type). Heretofore, only a few other similar high-grade neuroendocrine tumors with negative markers of C-cell derivation have been reported. In our case, the patient is cancer free five years after diagnosis, but in the other cases, the outcome was poor.

Learning points:

There are neuroendocrine carcinomas of the thyroid that do not produce calcitonin or calcitonin gene-related peptide.

This category of calcitonin-negative neuroendocrine carcinomas is heterogeneous, consisting of low- and high-grade tumors.

The high-grade neuroendocrine carcinomas of the thyroid are rare and generally have a poor prognosis. They are divided into small cell and non-small cell or large cell types.
A Catalogue of Putative cis-Regulatory Interactions Between Long Non-coding RNAs and Proximal Coding Genes Based on Correlative Analysis Across Diverse Human Tumors
Authors: Basu Swaraj , Larsson Erik 
Published: April 2018

Abstract
Antisense transcripts and other long non-coding RNAs are pervasive in mammalian cells, and some of these molecules have been proposed to regulate proximal protein-coding genes in cis. For example, non-coding transcription can contribute to inactivation of tumor suppressor genes in cancer, and antisense transcripts have been implicated in the epigenetic inactivation of imprinted genes. However, our knowledge is still limited and more such regulatory interactions likely await discovery. Here, we make use of available gene expression data from a large compendium of human tumors to generate hypotheses regarding non-coding-to-coding cis-regulatory relationships with emphasis on negative associations, as these are less likely to arise for reasons other than cis-regulation. We document a large number of possible regulatory interactions, including 193 coding/non-coding pairs that show expression patterns compatible with negative cis-regulation. Importantly, by this approach we capture several known cases, and many of the involved coding genes have known roles in cancer. Our study provides a large catalog of putative non-coding/coding cis-regulatory pairs that may serve as a basis for further experimental validation and characterization.
Fixed point results for ordered S-G-contractions in ordered metric spaces
Authors: Vetro Francesca 
Published: April 2018

In this paper, we prove existence and uniqueness of fixed point in the setting of ordered metric spaces. Precisely, we combine the recent notions of (F,φ)-contraction and Z-contraction in order to introduce the notion of ordered S-G-contraction. Then we use the notion of ordered S-G-contraction to show existence and uniqueness of fixed point. We stress that the notion of ordered S-G-contraction includes different types of ordered contractive conditions in the existing literature. Also, we give some examples and additional results in ordered partial metric spaces to support the new theory.
Investigation into Teachers’ European Competences
Authors: Jucevičienė Palmira 
Published: April 2018

Nowadays, more than ever before, development of the European competences has become extremely important. These competences are especially significant for the young generation, thus they became an important field for education researchers. The European competences are of particular importance to teachers who not only use them as citizens, but also influence others to develop them.
In order to develop the European competences Europe as a learning environment is necessary and it is being purposefully developed: the European Commission has established a broad range of programmes which help teachers to develop the necessary competences. Projects in the area have produced a significant amount of knowledge as asset which may be and is applied for the better Europe. The knowledge has become an open source of information for the teachers in the development of their European competences.
The aim of the current paper is to reveal what specific European competences teachers from EU countries recognize by self-reflection as an “asset in-use” in their professional daily lives. A survey was used as the main research method supported by the analysis of the scholarly literature.
Signs of Critical Reflection in Mathematical Experiential Learning Contexts
Authors: Grabauskienė Vaiva , Mockaitytė-Rastenienė Oksana 
Published: April 2018

In this article, we analyzed reflections of undergraduate students of Primary school education and also the reflections of gifted primary school children. The reflections were collected in those two subsamples separately, while learning Math in experiential way. For the suitability to observe critical reorganization of mathematical images, the scaling as a subject was chosen.
The process of learning in adults has a feature to encompass the critical reflection approach for the problem solving. The aim of our study was to shed light on differences and similarities between adults and gifted primary school children in mathematical reasoning.
We used the following methods: case study; observation; audio recordings; and qualitative analysis (i. e. content analysis). In whole study, 13 undergraduate students and 16 gifted children from III–IV grades took a part.
The results indicate that the main insights in the mathematical content were made while comparing measurements of different dimensions. The similarities between adults and children were found in how critical reorganization of mathematical images was done. The difference occurred in the extent of reasoning abstraction. Gifted children already at primary school years were able to formulate logical explanations into mathematical rules. However, for the children to make critical reflections, the experiential basis (practice) is obligatory. In contrast, adults used abstract reasoning even in experiential (practical) situations.
Phase II Study of Everolimus in Metastatic Malignant Melanoma (NCCTG-N0377, Alliance)
Authors: Vera Aguilera Jesus , Rao Ravi D. , Allred Jacob B. , Suman Vera J. , Windschitl Harold E. , Kaur Judith S. , Maples William J. , Lowe Val J. , Creagan Edward T. , Erickson Lori A. , Markovic Svetomir 
Published: April 2018

Abstract

Lessons Learned
Everolimus does not have sufficient activity to justify its use as single agent in metastatic melanoma. Patients treated with 10 mg per day dose were most likely to require dose reductions. Everolimus appeared to reduce the numbers of regulatory T cells in approximately half of the treated patients; unfortunately, these effects were not correlated with clinical outcomes.

Background
Everolimus (RAD-001) is an orally active rapamycin analogue shown in preclinical data to produce cytostatic cell inhibition, which may be potentially beneficial in treating melanoma. We conducted a phase II study to evaluate the efficacy and safety of everolimus in patients with unresectable metastatic melanoma (MM).

Methods
This study included two cohorts; cohort 1 received 30 mg of everolimus by mouth (PO) weekly, and cohort 2 was dosed with 10 mg of everolimus PO daily. The endpoints of the study were safety, 16-week progression-free survival (PFS), overall survival (OS), and measures of immunomodulatory/antiangiogenic properties with therapy. Tumor samples before therapy and at week 8 of treatment were analyzed. Peripheral blood plasma or mononuclear cell isolates collected prior to therapy and at weeks 8 and 16 and at time of tumor progression were analyzed for vascular endothelial growth factor and regulatory T-cell (Treg) measurements.

Results
A total of 53 patients were enrolled in cohort 1 (n = 24) and cohort 2 (n = 29). Only 2 patients of the first 20 patients enrolled in cohort 2 had treatment responses (25%; 95% confidence interval, 8.6%–49.1%); this result did not allow full accrual to cohort 2, as the study was terminated for futility. Median OS was 12.2 months for cohort 1 versus 8.1 months in cohort 2; no PFS advantage was seen in either group (2.1 months vs. 1.8 months). Dose-limiting toxicities included grade 4 myocardial ischemia (3.4%); grade 3 fatigue, mucositis, and hyperglycemia (10.3%); and anorexia and anemia (6.9%). Everolimus significantly reduced the number of Tregs in approximately half of the treated patients; however, these effects were not correlated with clinical outcomes.

Conclusion
Everolimus does not have sufficient single-agent activity in MM; however, we have identified evidence of biological activity to provide a potential rationale for future combination studies.
ПРОГНОЗУВАННЯ РЕСУРСНО-ДІЯЛЬНІСНОГО ПОТЕНЦІАЛУ ПІДПРИЄМСТВ МАШИНОБУДУВАННЯ НА ОСНОВІ СЦЕНАРНО-ДИНАМІЧНОГО МОДЕЛЮВАННЯ
Authors: Terovanesova О. Y. 
Published: April 2018

В роботі запропоновано науково-практичний підхід до прогнозування ресурсно-діяльнісного потенціалу підприємств машинобудування на основі сценарно-динамічного моделювання у контексті забезпечення ефективності управління та підвищення конкурентного статусу. Реалізована динамічна імітаційна модель, покладена в основу формування та розробки регулюючих заходів для підтримки належного рівня конкурентного статусу на основі трансформації потенціалу в активність та розбалансованості складових реалізації ресурсно-діяльнісного потенціалу. Побудована прогнозна модель дозволила оцінити поточне та прогнозне значення показників ефективності управління ресурсно-діяльнісним потенціалом за сценаріями впливу, зокрема удосконалити ефективність прийняття рішень з формування, вибору та реалізації конкурентних стратегій розвитку підприємств машинобудування на основі генерації сценаріїв для визначення вектору пріоритетного забезпечення конкурентного статусу в умовах швидкозмінних динамічних процесів.
De facto states and their socio-economic structures in the post-Soviet space after the annexation of Crimea
Authors: Baar Vladimír , Baarová Barbara 
Published: April 2018

The paper is focused on the economic problems of de facto states in the post-Soviet space after Russia's annexation of Crimea in 2014, creation of the Eurasian Economic Union in 2015 and the signing of the Deep and Comprehensive Free Trade Agreement between the EU and Georgia and Moldova with effect from 2016. It analyzes long-term economic strategies of Transnistria, Nagorno-Artsakh, South Ossetia-Alania and Abkhazia in the context of such changes. On the basis of statistical analyzes their economic problems, which are closely connected with developments in Russia and its geopolitical interests.
GOOD GOVERNMENT GOVERNANCE MENUJU PEMERINTAH YANG BEBAS KORUPSI, KOLUSI DAN NEPOTISME (KKN)
Authors: Sulistiani Dwi 
Published: April 2018

Penyempurnaan organisasi publik diharapkan mengarah kepada terbentuknya organisasi bersistem terbuka yang lebih fleksibel, mampu mengakomodasikan perubahan untuk kepentingan organisasi. Perubahan yang cepat dan tidak terduga membuka pandangan dan pikiran atas tuntutan adanya paradigma baru yang menghantarkan perjalanan menuju “<em>Good Government Governance</em>” (Tata Kelola Pemerintahan yang Baik), menuju Pemerintahan yang bebas dari Korupsi, Kolusi dan Nepotisme (KKN). Dalam organisasi modern berpijak pada konsep-konsep pemikiran manajemen modern, antara lain: menerapkan teknologi manajemen, berbasis pada asas demokratisasi, akuntabilitas, keterbukaan, transparasi, dan taat hukum. Terselenggaranya “<em>Good Government Governance</em>” merupakan prasyarat bagi setiap pemerintahan untuk mewujudkan aspirasi masyarakat dan mencapai tujuan serta cita-cita bangsa bernegara. Dalam rangka itulah diperlukan pengembangan dan penerapan sistem pertanggungjawaban yang tepat, jelas, dan legitimasi sehingga penyelenggaraan pemerintah dan pembangunan dapat berlangsung secara berdayaguna, berhasilguna, bersih dan bertanggungjawab, serta bebas dari Korupsi, Kolusi dan Nepotisme (KKN). Terwujudnya penerapan <em>Good Government Governance</em> dalam organisasi pemerintahan merupakan tuntutan bagi terselenggaranya manajemen pemerintahan dan pembangunan yang berdaya guna, berhasil guna, dan bebas Korupsi, Kolusi dan Nepotisme. Berkaitan dengan hal tersebut diperlukan sistem akutabilitas, transparansi, keterbukaan, dan aturan hukum yang baik dan sesuai dengan harapan / tuntutan kebutuhan pada seluruh jajaran aparatur negara.
1939-1945 Yılları Arasında Halkın Sosyo-Ekonomik Düzeyini İyileştirmeye Yönelik Bir Çözüm: Köylü Tipi ve Halk Tipi Elbise Uygulamaları
Authors: Utkugün Ceren , Ortak Şaban 
Published: April 2018

İkinci
Dünya Savaşı'nın başlamasıyla insanların gündelik hayatı savaş ortamından
etkilenmiştir. Bu süreçte hükümetler halkın yaşayış biçimlerinde çeşitli
kısıtlamalara gitmiş, birtakım yasaklar ve kurallar getirmişlerdir. Bu
kısıtlamalar giyim endüstrisinde de yoğun biçimde görülmüştür. Türkiye İkinci
Dünya Savaşı'na girmese de savaşa katılmış ve taraf olmuş devletler kadar
derinden etkilenmiştir. Savaştan kaynaklanan ekonomik sıkıntıların etkilerine
en çok maruz kalan kesimler dar ve sabit gelirliler olmuştur. Savaş yıllarında
gıda maddelerinde beliren darlık nedeniyle sıkıntı çeken vatandaşlar yükselen
enflasyon ile gıda dışı ihtiyaçlarını da temin edemez hale gelmiş, hayat
seviyelerini düşürmek zorunda kalmışlardır.

Savaş
yıllarında beslenme, ısınma, sağlık ihtiyaçları kadar kıyafet ihtiyaçlarını
gidermek de önemli bir sorun haline gelmiş; pek çok üründe karne sistemi
uygulamasına gidilmiş, dar gelirli halka ve memurlara yönelik giyim yardımı
kuponları da dağıtılmış, halkın karaborsadan etkilenme oranı azaltılmaya
çalışılmıştır. Ancak hammadde fiyatları artmış, bu durum her türlü ürünün
fiyatına yansımıştır. Ekonomik sıkıntı çeken halkın yaşam koşullarını
iyileştirmek üzere başka çareler de düşünülmüştür. Vatandaşa gıda maddeleri
temin etmeye çalışan savaş yılları hükümetleri, giyim eşyası konusunda da tüm
halkı kapsayan düşük fiyatlı üretim ve satış uygulamalarına başlamıştır. Köylü
ve şehirli halkın düşük fiyata giyinebilmesini sağlamak için “Köylü Tipi” ve “Halk Tipi Elbise” uygulamaları
yapılmıştır.