bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meta‐Analyses of Clinical Efficacy of Risankizumab and Adalimumab in Chronic Plaque Psoriasis: Supporting Evidence of Risankizumab Superiority
Authors: Witjes Han , Khatri Amit , Diderichsen Paul M. , Mandema Jaap , Othman Ahmed A. 
Published: September 2019

Risankizumab, an anti‐interleukin‐23 monoclonal antibody, achieved significantly (P < 0.001) greater Psoriasis Area and Severity Index (PASI) and static Physician Global Assessment (sPGA) clear or almost clear (0/1) responses than adalimumab in a phase III trial in patients with moderate‐to‐severe psoriasis. Meta‐analyses of the PASI 50, PASI 75, PASI 90, PASI 100, and sPGA0/1 responses after 16 weeks of treatment from eight (three for risankizumab and five for adalimumab) randomized, placebo‐controlled trials were conducted to estimate the efficacy difference between risankizumab and adalimumab. For PASI 75, PASI 90, PASI 100, and sPGA0/1 responses, the estimated effect differences (95% confidence interval) between risankizumab and adalimumab were 15.2% (10.1%, 20.4%), 23.7% (15.7%, 31.2%), 20.8% (13.0%, 28.7%), and 20.1% (13.7%, 26.1%), respectively. These results were consistent with the observed efficacy difference from the head‐to‐head phase III trial, which was not included in the meta‐analyses, providing independent, confirmatory evidence of the superior efficacy of risankizumab compared with adalimumab for treatment of moderate‐to‐severe psoriasis.
Corporate culture in small and medium enterprises: Application of corporate social responsibility theory
Authors: Getele Gutama Kusse , Li Tieke , Arrive Tsitaire Jean 
Published: September 2019

AbstractThe small and medium enterprises play a major role in creating jobs and therefore minimize the unemployment rate to attain corporate sustainable development. Its attention on corporate social responsibility is in doubt about their corporate culture including corporate image and motivation of employees. The purpose of this study is to identify the impact of corporate social responsibility in small and medium enterprises image and employees motivation in terms of environmental and social practices dimension. A quantitative sampling method of 34 small and medium enterprises in the global south was used. The result of this research shows that the variables of environmental dimensions have a significant impact on image and motivation than the variables of social dimensions such as human resources management and community practices. The study indicates that having corporate social responsibility in terms of environmental practices is the main factor in the effective business image and employees motivation.
Trust‐based forest monitoring system using Internet of Things
Authors: Vikash  , Varma Shirshu 
Published: September 2019

SummaryWe introduce trust‐based event‐driven (TBED) infrastructure for forest monitoring and reporting. TBED endows the real‐time local monitoring along with spatial monitoring. None of the work till now considers both local and spatial monitoring. To the best of our knowledge, TBED is the first attempt in this domain, where event‐related information is reported to the consumers along with the effective area. TBED is based on the event‐driven architecture in which device management and monitoring authorities, middleware event handler (MEH), and consumers are involved. Additionally, we present a trust mechanism to evaluate the sensor node trust for reliable information. At last, we present a case study of fire monitoring to depict the real‐life scenario.
Cytological appearance of pancreatic cystosis on fine‐needle aspiration
Authors: Aly F. Zahra , Mostofizadeh Sayedamin , Jawaid Salmaan 
Published: September 2019

AbstractA 22‐year‐old Caucasian male with cystic fibrosis and recently diagnosed insulin‐dependent diabetes mellitus underwent magnetic resonance imaging (MRI) and was found to have multiple cystic lesions in the pancreas. Endoscopic ultrasound evaluation revealed multiple macro‐ and microcystic components without mural nodules. One of the cysts in the body of the pancreas was in clear direct communication with the nondilated main pancreatic duct. Fine‐needle aspiration (FNA) of two cysts was performed and showed foamy macrophages and rare ductal as well as acinar cells. Cell blocks showed nonpolarizable pink crystalloid material and small nonlaminated concretions consistent with inspissated secretions. Special stains for chymotrypsin and trypsin highlighted the acinar cells. Periodic acid Schiff, with and without diastase, was negative. Biopsy of the cyst wall showed ductal epithelial cells with underlying fibrotic stroma. This is the first description of the FNA appearance of pancreatic cystosis. We discuss the cytological differential diagnosis of cystic lesions of the pancreas and the biochemical as well as imaging findings used to arrive at the diagnosis.
Kinematic characteristics of second‐order motor planning and performance in 6‐ and 10‐year‐old children and adults: Effects of age and task constraints
Authors: Domellöf Erik , Bäckström Anna , Johansson Anna‐Maria , Rönnqvist Louise , von Hofsten Claes , Rosander Kerstin 
Published: September 2019

AbstractThis study explored age‐related differences in motor planning as expressed in arm‐hand kinematics during a sequential peg moving task with varying demands on goal insertion complexity (second‐order planning). The peg was a vertical cylinder with either a circular or semicircular base. The task was to transport the peg between two positions and rotate it various amounts horizontally before fitting into its final position. The amount of rotation required was either 0°, 90°, 180°, or −90°. The reaching for the peg, the displacement of it, and the way the rotation was accomplished was analyzed. Assessments of end state comfort, goal interpretation errors, and type of grip used were also included. Participants were two groups of typically developing children, one younger (Mage = 6.7 years) and one older (Mage = 10.3 years), and one adult group (Mage = 34.9 years). The children, particularly 6‐year‐olds, displayed less efficient prehensile movement organization than adults. Related to less efficient motor planning, 6‐year‐olds, mainly, had shorter reach‐to‐grasp onset latencies, higher velocities, and shorter time to peak velocities, and longer grasp durations than adults. Importantly, the adults rotated the peg during transport. In contrast, the children made corrective rotations after the hand had arrived at the goal.
Optimizing eating disorder treatment outcomes for individuals identified via screening: An idea worth researching
Authors: Taylor Craig Barr , Graham Andrea K. , Fitzsimmons‐Craft Ellen E. , Sadeh‐Sharvit Shiri , Balantekin Katherine N. , Flatt Rachael E. , Goel Neha J. , Monterubio Grace E. , Topooco Naira , Karam Anna M. , Firebaugh Marie‐Laure , Ruzek Josef I. , Funk Burkhardt , Oldenburg Brian , Wilfley Denise E. , Jacobi Corinna 
Published: September 2019

AbstractIn recent years, online screens have been commonly used to identify individuals who may have eating disorders (EDs), many of whom may be interested in treatment. We describe a new empirical approach that takes advantage of current evidence on empirically supported, effective treatments, while at the same time, uses modern statistical frameworks and experimental designs, data‐driven science, and user‐centered design methods to study ways to expand the reach of programs, enhance our understanding of what works for whom, and improve outcomes, overall and in subpopulations. The research would focus on individuals with EDs identified through screening and would use continuously monitored data, and interactions of interventions/approaches to optimize reach, uptake, engagement, and outcome. Outcome would be assessed at the population, rather than individual level. The idea worth researching is to determine if an optimization outcome model produces significantly higher rates of clinical improvement at a population level than do current approaches, in which traditional interventions are only offered to the few people who are interested in and able to access them.
Endangered but genetically stable—Erythrophleum fordii within Feng Shui woodlands in suburbanized villages
Authors: Wang Zheng‐Feng , Liu Hai‐Lin , Dai Se‐Ping , Cao Hong‐Lin , Wang Rui‐Jiang , Wang Zhang‐Ming 
Published: September 2019

AbstractFeng Shui woodlands are naturally or artificially formed green areas in southern China. They are precious for maintaining ecosystem balance in modern semiurban environments. However, they are generally small and geographically isolated from each other, and the status of genetic diversity of the plant species within them has been almost neglected. Therefore, we studied the genetic diversity of the endangered Erythrophleum fordii in eight Feng Shui woodlands (a total of 1,061 individuals) in Guangzhou, a large city in southern China, using microsatellites. For comparison, one population with 33 individuals sampled in a nature reserve was also studied. Although our results indicate that significant demographic declines occurred historically in E. fordii, such declines have not resulted in consistent reductions in genetic variation over generations in Feng Shui populations in the recent past, and the levels of genetic variation in these populations were higher than or comparable to the genetic variation of the population in the nature reserve. In addition, our parentage and paternity analyses indicated widespread and potential long‐distance pollen flow within one Feng Shui woodland, indicating the presence of an unbroken pollination network, which would at least partially alleviate the genetic erosion due to habitat fragmentation and the unequal gene contributions of E. fordii parents to their progenies when favorable recruitment habitats are absent under most of the parent trees. Overall, our results suggest that E. fordii in Feng Shui woodlands may not be driven to extinction in the near future. Nevertheless, uncontrolled fast urban development with a lack of awareness of Feng Shui woodlands will cause the local extinction of E. fordii, which has already happened in some Feng Shui woodlands.
How do trees respond to species mixing in experimental compared to observational studies?
Authors: Kambach Stephan , Allan Eric , Bilodeau‐Gauthier Simon , Coomes David A. , Haase Josephine , Jucker Tommaso , Kunstler Georges , Müller Sandra , Nock Charles , Paquette Alain , van der Plas Fons , Ratcliffe Sophia , Roger Fabian , Ruiz‐Benito Paloma , Scherer‐Lorenzen Michael , Auge Harald , Bouriaud Olivier , Castagneyrol Bastien , Dahlgren Jonas , Gamfeldt Lars , Jactel Hervé , Kändler Gerald , Koricheva Julia , Lehtonen Aleksi , Muys Bart , Ponette Quentin , Setiawan Nuri , Van de Peer Thomas , Verheyen Kris , Zavala Miguel A. , Bruelheide Helge 
Published: September 2019

AbstractFor decades, ecologists have investigated the effects of tree species diversity on tree productivity at different scales and with different approaches ranging from observational to experimental study designs. Using data from five European national forest inventories (16,773 plots), six tree species diversity experiments (584 plots), and six networks of comparative plots (169 plots), we tested whether tree species growth responses to species mixing are consistent and therefore transferrable between those different research approaches. Our results confirm the general positive effect of tree species mixing on species growth (16% on average) but we found no consistency in species‐specific responses to mixing between any of the three approaches, even after restricting comparisons to only those plots that shared similar mixtures compositions and forest types. These findings highlight the necessity to consider results from different research approaches when selecting species mixtures that should maximize positive forest biodiversity and functioning relationships.
Population genetic structures of two ecologically distinct species Betula platyphylla and B. ermanii inferred based on nuclear and chloroplast DNA markers
Authors: Wang Hua‐Ying , Yin Xiao , Yin Dong‐Xu , Li Lin , Xiao Hong‐Xing 
Published: September 2019

AbstractClimatic oscillations during the last glacial maximum (LGM) significantly affected the distribution patterns and genetic structure of extant plants. Northeast China (NEC) is a major biodiversity center in East Asia, and the influence of historical climate change on NEC populations is critical for understanding species responses to future climate change. However, only a few phylogeographic studies of cool temperate deciduous tree species have been conducted in the area, and results are inconsistent for species with different niches or distribution areas. We employed multiple chloroplast and nuclear markers to investigate the genetic structure of two ecologically contrasting species, Betula platyphylla and B. ermanii, in NEC. Rare haplotypes were identified in the chloroplast genome of these species, and both exhibited high levels of nucleotide diversity based on a fragment of the nuclear gene G3PDH and microsatellites. Moreover, significant phylogeographic structure was detected for B. platyphylla, suggesting that these populations had recolonized from independent glacial refuges, whereas no genetic structure was found for B. ermanii.OPEN RESEARCH BADGES

The nSSR datasets used in the current study and the table of pairwise FST (below diagonal) and its standardized F'ST (above diagonal) among 25 populations based on seven SSRs are available from the Dryad (DOI: https://doi.org/10.5061/dryad.230d176). Sequences generated from this study were deposited in GenBank under Accession nos. KY199568–KY200162 and MK819541–MK819970.
Species energy and Thermal Performance Theory predict 20‐yr changes in ant community abundance and richness
Authors: Kaspari Michael , Bujan Jelena , Roeder Karl A. , de Beurs Kirsten , Weiser Michael D. 
Published: September 2019

AbstractIn an era of rapid climate change, and with it concern over insect declines, we used two theories to predict 20‐yr changes in 34 North American ant communities. The ecosystems, from deserts to hardwood forests, were first surveyed in the 1990s. When resurveyed in 2016–2017, they averaged 1°C warmer with 200 g C·m−2·yr−1 higher plant productivity. Ant colony abundance changed from −49% to +61%. Consistent with Thermal Performance Theory, colony abundance increased with temperature increases < 1°C, then decreased as a site's mean monthly temperature change increased up to +2.4°C. Consistent with Species Energy Theory, (1) ant abundance tracked changes in a measure of energy availability (net aboveground productivity, g C·m−2·yr−1) and (2) increases in colony abundance drove increases in local plot‐ and transect‐level species richness but not that of Chao 2, an estimate of the size of the species pool. Even after accounting for these drivers, local species richness was still higher ~20 yr after the original surveys, likely due to the increased activity of ant workers. These results suggest community changes are predictable using theory from geographical ecology, and that warming can first enhance but may ultimately decrease the abundance of this important insect taxon.
An Electrochemiluminesence Chiral Sensor for Propranolol Enantiomers Based on Functionalized Graphite‐like Carbon Nitride Nanosheets
Authors: Zhu Shu , Ran Peiyao , Wu Jingling , Chen Min , Fu Yingzi 
Published: September 2019

AbstractGraphite‐like carbon nitride nanosheets (g‐C3N4) have been attracted considerable attention for their applications in catalysis and electrochemiluminesence (ECL) sensor. In this paper, a facile solvothermal method was employed to prepare the functionalized nanocomposites with metal salts cadmium carbonate (CdCO3) and g‐C3N4 hybrids (g‐C3N4‐CdCO3). The prepared materials were characterized by scanning electron microscope (SEM), X‐ray energy dispersive spectroscopy (EDX) and Fourier transform infrared spectra (FTIR). The nanocomposites was used not only as a new type luminophore but also as a chiral selector in this simple and sensitive ECL chiral sensor system for the recognition and detection of propranolol (Pro) enantiomers via quenching effect. The obvious difference of ECL signal of S‐Pro and R‐Pro was obtained. Thus, the sensor had the ability to distinguish Pro enantiomers. The mechanism of recognition was discussed by the theoretical calculation of binding constant and the water contact angle experiments. The sensor for Pro enantiomers was developed at wide concentration range from 0.001 to 1 mmol⋅L−1. The sensor with excellent sensitivity, stability and reproducibility provide a new strategy based on ECL for chiral recognition and the ECL chiral sensor.
Assessment of agricultural biomass residues to replace fossil fuel and hydroelectric power energy: A spatial approach
Authors: Romero Cristhy Willy da Silva , Berni Mauro Donizeti , Figueiredo Gleyce Kelly Dantas Araujo , Franco Telma Teixeira , Lamparelli Rubens Augusto Camargo 
Published: September 2019

AbstractDespite the recent discoveries of considerable fossil fuel reserves, Brazil is one of the only great economic and industrial powers with very high amounts of renewable energy in its electricity matrix. Approximately 79.3% of the electric energy supply comes from renewable resources, of which hydroelectric power represents 70.6%. The two primary concerns regarding hydroelectricity are the damage caused to the environment by the construction of dams and the uncertainty of the supply in cases of long drought seasons. This article presents an analysis on the availability and energy exploitation of sugarcane straw and forest residues derived from eucalyptus for decentralized generation using a Geographic Information System–based model. The potential bioelectricity and bioethanol production from sugarcane and eucalyptus biomass in the Administrative Region of Campinas (ARC) is higher than the demand in this region. The results provide guidelines for designing alternatives to the intended Nationally Determined Contributions in Brazil within the scope of the ARC, and they can be used to provide energy empowerment, electric matrix diversification, and new policies that address the residue availability and demand.
Xylo‐oligosaccharides as texture modifier compounds in aqueous media and in combination with food thickeners
Authors: Penksza Péter , Juhász Réka , Szabó‐Nótin Beatrix , Sipos László 
Published: September 2019

AbstractPresent study introduces the previously not‐described rheological properties of a nondigestible oligosaccharide: xylo‐oligosaccharide which is a novel food ingredient in Europe. Significant differences were observed among viscosity of solutions of different formulas (liquid or powder) of XOS. Thickening potential of XOS in aqueous media compared to that of sucrose (Suc) or fructo‐oligosaccharides strongly depends on utilization level: At low concentration, XOS proved to be weaker while at high concentration to be stronger than fructo‐oligosaccharides. Differences in viscosity of XOS, FOS, and sucrose were much higher at below 60°C than at higher temperatures. Storage and loss modulii of xanthan gum gels were not influenced while those of locust bean gum were affected negatively by XOS addition. Addition of XOS at low concentrations did not decrease gelatin gel strength but increased gelatin gel stability against mechanical stress. XOS proved to have different rheological behavior from previously used oligosaccharides.
Analysis of the impact of determinants of kosherness on the content of macro‐ and microelements in beef
Authors: Rudy Mariusz , Żurek Jagoda , Stanisławczyk Renata , Gil Marian , Duma‐Kocan Paulina , Zaguła Grzegorz , Rudy Stanisław 
Published: September 2019

AbstractThere are no studies in the literature that comprehensively present the impact of factors related only to kosher slaughter on the content of minerals in beef. Therefore, learning the impact of such kosher determinants of beef as follows: no stunning during slaughter, cattle category, muscle, or the so‐called kosher treatment for mineral content in beef has an original character. In this connection, the aim of the research was a comprehensive analysis of the impact of kosher determinants (slaughter type, muscle, cattle category, and technological treatment) on the content of selected macro‐ and microelements in beef. On the content of minerals in muscles obtained from beef carcasses, the statistically significant (p < .05) impact was found in the case of slaughter type for such elements as: K, P, and Na. Higher content of phosphorus, potassium, and sodium was found in muscles of heifers and bulls from standard slaughter, compared with the amount of these elements determined in muscles of cattle from kosher slaughter. In turn, statistically significant (p < .05) impact of cattle sex was confirmed only in the case of iron and molybdenum content in beef. Higher amounts of these elements were determined in muscle from heifer carcasses (excluding the molybdenum content in MLT muscle of heifer carcasses from kosher slaughter). The process of koshering (soaking in brine) causes approximately 10‐fold increase in the amount of sodium in beef, regardless of the muscle or gender of cattle. The statistically significant impact of muscle was confirmed only in the case of zinc content. In the authors’ own research, there was found no statistically significant impact of the interaction effects between the analyzed factors (S × G, S × M, G × M, and S × G × M) on the content of particular mineral components.
Programs trades and trade regulation: An evidence of the Korean securities market
Authors: Eom Cheoljun , Jordan Steven J. , Lee Woo‐Baik , Park Jong Won 
Published: September 2019

AbstractThis study addresses the effects of program trade regulation during large market moves. To address this issue, we analyze the effect of sidecars (halts that only affect program trades) on trade imbalance using Korean intraday data. We find that sidecars, as currently designed to halt all program trades, are not effective at controlling trade imbalance around volatile markets. Resolution of trade imbalance is more effective when program trade is unrestricted. Program trade, at least a subset, provides liquidity when it is at a premium. We conclude that current sidecars should be more carefully crafted as some program trades are market stabilizing.
Effect of nonlinear thermal radiation on silver and copper water nanofluid flow due to a rotating disk with variable thickness in the presence of nonuniform heat source/sink using the homotopy analysis method
Authors: Sravanthi C. S. 
Published: September 2019

AbstractAn analysis of a steady axisymmetric heat transfer nanofluid flow due to a rotating disk having variable thickness in the presence of nonlinear radiation and nonuniform heat source/sink is presented. Water with Copper (Cu) and Silver (Ag) nanoparticles are utilized in the investigation. The governing equations along with boundary conditions are solved using the homotopy analysis method. A parametric study of the physical parameters is done and results are displayed in the form of graphs. The findings indicate that nonlinear radiation has a significant effect on temperature as well as on wall heat transfer when compared with linear case, which is more useful in few engineering processes.