bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Systematic Review and Meta-Analysis of Anterior Versus Lateral Approach for Laparoscopic Splenectomy
Authors: Rehman Sheik , Hajibandeh Shahin , Hajibandeh Shahab 
Published: January 2019

Background:
As the experience grew with laparoscopic splenectomy (LS) more surgeons appreciate the advantages of lateral approach compared with conventional anterior approach. In view of this we aimed to compare anterior approach and lateral approach in LS.

Methods:
We conducted a search of electronic information sources to identify all randomized controlled trials (RCTs) and observational studies comparing anterior and lateral approach in patients undergoing LS. Primary outcomes included need for blood transfusion, intraoperative blood loss, and conversion to open surgery. The secondary outcomes included postoperative morbidity, operative time, time to oral intake, length of hospital stay, need for reoperation, and mortality. Random or fixed-effects modeling were applied to calculate pooled outcome data.

Results:
We identified 1 RCT and 4 retrospective observational studies, enrolling 728 patients. The baseline characteristics included populations in both groups were comparable. Anterior approach was associated with higher need for blood transfusion [odds ratio (OR), 4.83, 95% confidence interval (CI), 2.31-10.97; P=0.0001]; higher risks of intraoperative blood loss [mean difference (MD), 101.06, 95% CI, 52.05-150.06; P=0.0001], conversion to open surgery (OR, 3.33, 95% CI, −1.32 to 8.43; P=0.01), postoperative morbidity (OR, 3.86, 95% CI, −2.23 to 6.67; P=0.00001) and need for reoperation (OR, 6.91, 95% CI, −1.07 to 44.6; P=0.04); longer operative time (MD, 2.51, 95% CI, −1.43 to 3.59; P=0.00001), time to oral intake (MD, 0.60, 95% CI, −0.14 to −1.07; P=0.01), and length of stay (MD, 2.52, 95% CI, −1.43 to 3.59; P=0.00001) compared with lateral approach. There was no difference in the risk of mortality between the 2 groups (risk difference, 0.00, 95% CI, −0.01 to 0.02; P=0.61).

Conclusions:
The best available evidence suggests that the lateral approach is superior to anterior approach in LS as indicated by better access, more secure hemostasis, less conversion to open surgery, less morbidity, earlier recovery, and shorter length of hospital stay. The quality of the available evidence is moderate; high-quality RCTs are required to provide more robust basis for definite conclusions.
Chromatin modifiers alter recombination between divergent DNA sequences
Authors: Chakraborty Ujani , Mackenroth Beata , Shalloway David , Alani Eric 
Published: January 2019

AbstractRecombination between divergent DNA sequences is actively prevented by heteroduplex rejection mechanisms. In baker’s yeast such anti-recombination mechanisms can be initiated by the recognition of DNA mismatches in heteroduplex DNA by MSH proteins, followed by recruitment of the Sgs1-Top3-Rmi1 helicase-topoisomerase complex to unwind the recombination intermediate. We previously showed that the repair/rejection decision during single-strand annealing recombination is temporally regulated by MSH protein levels and by factors that excise non-homologous single-stranded tails. These observations, coupled with recent studies indicating that mismatch repair factors interact with components of the histone chaperone machinery, encouraged us to explore roles for epigenetic factors and chromatin conformation in regulating the decision to reject vs. repair recombination between divergent DNA substrates. This work involved the use of an inverted repeat recombination assay thought to measure sister chromatid repair during DNA replication. Our observations are consistent with the histone chaperones CAF-1 and Rtt106 and the histone deacetylase Sir2 acting to suppress heteroduplex rejection and the Rpd3, Hst3 and Hst4 deacetylases acting to promote heteroduplex rejection. These observations and double mutant analysis have led to a model in which nucleosomes located at DNA lesions stabilize recombination intermediates and compete with mismatch repair factors that mediate heteroduplex rejection.SummaryRecombination between divergent DNA sequences is actively prevented by heteroduplex rejection mechanisms. In this study we explored roles for epigenetic factors and chromatin conformation in regulating the decision to reject vs. repair recombination between divergent DNA substrates. Our observations are consistent with the histone chaperones CAF-1 and Rtt106 and the histone deacetylase Sir2 acting to suppress heteroduplex rejection and the Rpd3, Hst3 and Hst4 deacetylases acting to promote heteroduplex rejection. These observations have led to a model in which nucleosomes located at DNA lesions stabilize recombination intermediates and compete with mismatch repair factors that mediate heteroduplex rejection.
Comparative Population Genomics of Bread Wheat(Triticum aestivum)Reveals Its Cultivation and Breeding History in China
Authors: Chen Haofeng , Jiao Chengzhi , Wang Ying , Wang Yuange , Tian Caihuan , Yu Haopeng , Wang Jing , Wang Xiangfeng , Lu Fei , Fu Xiangdong , Xue Yongbiao , Jiang Wenkai , Ling Hongqing , Lu Hongfeng , Jiao Yuling 
Published: January 2019

AbstractThe evolution of bread wheat(Triticum aestivum)is distinctive in that domestication, natural hybridization, and allopolyploid speciation have all had significant effects on the diversification of its genome. Wheat was spread around the world by humans and has been cultivated in China for ~4,600 years. Here, we report a comprehensive assessment of the evolution of wheat based on the genome-wide resequencing of 120 representative landraces and elite wheat accessions from China and other representative regions. We found substantially higher genetic diversity in the A and B subgenomes than in the D subgenome. Notably, the A and B subgenomes of the modern Chinese elite cultivars were mainly derived from European landraces, while Chinese landraces had a greater contribution to their D subgenomes. The duplicated copies of homoeologous genes from the A, B, and D subgenomes were commonly found to be under different levels of selection. Our genome-wide assessment of the genetic changes associated with wheat breeding in China provides new strategies and practical targets for future breeding.
Dowsing for salinity tolerance related genes in chickpea through genome wide association and in silico PCR analysis
Authors: Ahmed Shaimaa M. , Alsamman A.M. , Mubarak M.H. , Badawy M.A. , Kord M.A. , Momtaz O.A. , Hamwieh A. 
Published: January 2019

AbstractSoil salinity is a major abiotic stress severely limits agricultural crop production throughout the world, and the stress is increasing particularly in the irrigated agricultural areas. Chickpea (Cicer arietinum L.) is an important grain legume that plays a significant role in the nutrition of the developing world. In this study, we used a chickpea subset collected from the genebank of the International Center for Agricultural Research in the Dry Area (ICARDA). This collection was selected by using the focused identification of germplasm strategy (FIGS). The subset included 138 genotypes which have been screened in the open field (Arish, Sinai, Egypt) and in the greenhouse (Giza, Egypt) by using the hydroponic system at 100 mM NaCl concentration. The experiment was laid out in randomized alpha lattice design in two replications. The molecular characterization was done by using sixteen SSR markers (collected from QTL conferred salinity tolerance in chickpea), 2,500 SNP and 3,031 DArT markers which have been developed and used for association study. The results indicated significant differences between the chickpea genotypes. Based on the average of the two hydroponic and field experiments, seven tolerant genotypes IGs (70782, 70430, 70764, 117703, 6057, 8447 and 70249) have been identified. The data analysis indicated one SSR (TAA170), three DArT (DART2393, DART769 and DART2009) and eleven SNP markers (SNP2021, SNP1268, SNP1451, SNP1487, SNP1667, SNP2095, SNP190, SNP2247 SNP1947, SNP2331 and SNP948) were associated with salinity tolerance. The flanking regions of these markers revealed genes with a known role in the salinity tolerance, which could be candidates for marker-assisted selection in chickpea breeding programs.
Changing environments and genetic variation: inbreeding does not compromise short-term physiological responses
Authors: Buckley James , Daly Rónán , Cobbold Christina , Burgess Karl , Mable Barbara K. 
Published: January 2019

ABSTRACTSelfing plant lineages are surprisingly widespread and successful in a broad range of environments, despite showing reduced genetic diversity, which is predicted to reduce long-term evolutionary potential. However, short-term capacity to respond appropriately to new conditions might not require high levels of standing genetic variation. The purpose of this study was to directly test whether mating system variation and its associated changes in genetic variability in natural populations affected responses to short-term environmental challenges.We compared relative fitness and metabolome profiles of naturally outbreeding (genetically diverse) and inbreeding (genetically depauperate) populations of a long-lived perennial plant, Arabidopsis lyrata, under constant growth chamber conditions and an outdoor common garden environment outside its native range.We found no effect of mating system on survival or reproductive output, although several phenological traits showed different associations with latitude for outcrossing and inbreeding populations. Natural inbreeding had no effect on the plasticity of physiological responses, using either multivariate approaches or analysis of variation in individual metabolites. Moreover, while both growing environment and time significantly affected the relative abundance of individual metabolites, inbreeding populations responded similarly to outbreeding populations, suggesting adaptation to the outdoor environment, regardless of mating system.We conclude that low genetic diversity in naturally inbred populations may not compromise fitness or short-term capacity for appropriate physiological responses to environmental change. The absence of natural costs of inbreeding could help to explain the global success of clonal or asexual mating strategies for adapting to a wide range of environments.
N-terminal mutants of human apolipoprotein A-I: structural perturbations associated to protein misfolding
Authors: Gaddi Gisela M. , Gisonno Romina , Rosú Silvana A. , Curto Lucrecia M. , Elías Esteban E. , Prieto Eduardo D. , Schinella Guillermo R. , Finarelli Gabriela S. , Cortez M. Fernanda , Ramella Nahuel A. , Tricerri M. Alejandra 
Published: January 2019

AbstractSince the early description of different human apolipoprotein A-I variants associated to amyloidosis, the reason that determines its deposition inducing organ failure has been under research. To shed light into the events associated to protein aggregation, we studied the effect of the structural perturbations induced by the replacement of a Leucine in position 60 by an Arginine as it occurs in the natural amyloidogenic variant (L60R). Circular dichroism, intrinsic fluorescence measurements and assays of binding to ligands indicate that L60R is more unstable, more sensitive to proteolysis and interacts with sodium dodecyl sulfate (a model of negative lipids) more than the protein with the native sequence and other natural variant tested, involving a replacement of a Trytophan by and Arginine in the amino acid 50 (W50R). In addition, the small structural rearrangement observed under physiological pH leads to the release of tumor necrosis factor α and interleukin-lβ from a model of macrophages. Our results strongly suggest that the chronic disease may be a consequence of the loss in the native conformation which alters the equilibrium among native and cytotoxic proteins conformation.
Training load and body composition in adults practicing cyclical exercises
Authors: da Silva Raquel Suelen Brito , de Souza Marizângela Ferreira , Silveira Costa Matheus da , Maciel Franca Gisele Augusta , Cardoso Glêbia Alexa , Batista Joane Raquel Estrela , Arruda Lopes Carolina Farias , Barbosa Francisca Karinny Lemos , Silva Alexandre Sérgio 
Published: January 2019

AbstractAlthough meta-analyzes point to a weight loss of no more than 3 kg to exercise, body fat of the athletes are below of the population. Then training load may be a determining factor in body composition. This study verified if dose of physical training adopted by exercise practitioners is determinant in body composition. Was a cross-sectional retrospective study carried out with 122 individuals (45.8 ± 13.0 years, 50 men) who practiced cyclic exercises (running, walking or cycling) randomly recruited in six regions which the city was geographically divided. Caloric expenditure was estimated in the trainings based on the frequency, intensity and duration of the exercises and the body composition was assessed by electrical bioimpedance. The subjects practiced 4.3 ± 1.5 weekly sessions, with mean duration of 56.7 ± 28.2 minutes/session and caloric expenditure/day of 410.2 ± 384.1 kcal/day. Linear regression test revealed a negative correlation (p=0.000) between the mean daily expenditure and all measures of adiposity tested (absolute and relative body fat and visceral fat), and evidenced that the training load explains 56% of the proposed model. When adjusted for sex, the correlation remained in men and disappeared in women. Men’s with energy expenditure higher than 785 kcal/day presented lower fat stores than congeners with minor diary training load. Conclude that training load adopted by physical exercise practitioners is an influencing factor in the body composition of men, but not of women. Load adopted in conventional programs training seems insufficient to produce adequate body composition.
Corrosion resistance and mechanism of micro-nano structure super-hydrophobic surface prepared by laser etching combined with coating process
Authors: Zhang Qianqian , Zhang Huichen 
Published: January 2019

Purpose
The purpose of this paper is to evaluate the effect of micro-nano mixed super-hydrophobic structure on corrosion resistance and mechanism of magnesium alloys.

Design/methodology/approach
A super-hydrophobic surface was fabricated on AZ91 and WE43 magnesium alloys by laser etching and micro-arc oxidation (MAO) with SiO2 nanoparticles coating and low surface energy material modification. The corrosion resistance properties of the prepared super-hydrophobic surfaces were studied based on polarization curves and immersion tests.

Findings
Compared with bare substrates, the corrosion resistance of super-hydrophobic surfaces was improved significantly. The corrosion resistance of super-hydrophobic surface is related to micro-nano composite structure, static contact angle and pretreatment method. The more uniform the microstructure and the larger the static contact angle, the better the corrosion resistance of the super-hydrophobic surface. The corrosion resistance of super-hydrophobic by MAO is better than that of laser machining. Corrosion of super-hydrophobic surface can be divided into air valley action, physical shielding, pretreatment layer action and substrate corrosion.

Originality/value
The super-hydrophobic coatings can reduce the contact of matrix with water so that a super-hydrophobic coating would be an effective way for magnesium alloy anti-corrosion. Therefore, the corrosion resistance properties and mechanism of the prepared super-hydrophobic magnesium alloys were investigated in detail.
Acceptance and adoption of open access publishing by researchers in India
Authors: Nazim Mohammad , Zia Sana 
Published: January 2019

PurposeThis paper aims to examine the level of open access (OA) adoption by researchers in Indian Institutes of Technology (IITs), identify predictors of OA status (OA vs non-OA) and explore the availability of OA versions of the articles and venues used by the researches for hosting of their articles.Design/methodology/approachArticles contributed by the researchers in IITs were searched using an advance search option in the Web of Science Core collection database. The search was restricted to journal articles published in English language in the year 2015. Of the 10,049 articles retrieved, 1,023 (10 per cent of the total) were chosen randomly. Articles selected after randomizations were exported to MS Excel for further analyses. Title of each article was searched in Google Scholar to assess its OA availability and venues used by the author for self-archiving. Details of ten articles could not be traced in Google Scholar, and they were excluded from the analysis. Based on the analysis of URLs, all OA articles were classified into three categories: gold OA, green OA and both gold and green OA. The OA articles available through green route were further classified into six categories based on the analysis of the websites and the self-archiving venues used by the authors: institutional repository, subject repository, researcher or scholar’s website, organizational website, ResearchGate and other websites.FindingsOf 1,013 articles examined, OA versions were found for 68.70 per cent of articles. Of the total OA articles, 10.26 per cent articles were available through gold OA and 58.44 per cent were available through green OA, while remaining 6.21 per cent were available via both gold and green OA routes. Although researchers use different venues for self-archiving their articles, ResearchGate and institutional repositories are the most preferred choices by the researchers in IITs. Researchers in IITs are seemed to be unaware of the self-archiving policies of publishers, as more than 85 per cent self-archived articles were found as final PDF versions that are normally not allowed by the publishers.Research limitations/implicationsThis study is limited to IITs, but it offers theoretical implications for extending its scope to different subjects and institutes. The findings of the study may be useful for the publishers and institutions for formulating OA policies. The findings of the study might be used for raising awareness of OA among researchers and encouraging them to contribute their research outcome in OA outlets.Originality/valueThis is the first study in India focusing on the availability of OA research.
The emergence of Chinese entrepreneurs: social connections and innovation
Authors: Dai Shuanping , Wang Yuanyuan , Liu Yang 
Published: January 2019

Purpose
This paper aims to explore empirically the emergence of entrepreneurs in China’s transition context since the 1980s.

Design/methodology/approach
This paper applies the China Private Enterprises Survey Database and historical evidence and Chi-Square test to identify the emergence patterns of China’s entrepreneurs in different historical stages.

Findings
This longitudinal study finds that factors such as working experience, education background and social connection had strong influences on entrepreneurship, but the impact of these have varied significantly along with institutional changes over the past three decades. It also identifies that the majority of emergent entrepreneurs were formerly low-level public servants and high-qualified managers in state-owned enterprises. Additionally, significant trends including an increasing number of female entrepreneurs, a decreasing impact from political networks, improving investment in innovation and diversifying financial sources are also found.

Originality/value
This paper is the first to apply the Chinese Private Enterprises Survey database to investigate the emergence patterns of China’s entrepreneurs in different historical stages after the 1978 reform.
Fuzzy overall equipment effectiveness and line performance measurement using artificial neural network
Authors: Fekri Sari Mahsa , Avakh Darestani Soroush 
Published: January 2019

Purpose
The overall equipment effectiveness (OEE) is a powerful metric in production as well as one of the methods in evaluating function for measuring productivity in the production process. In the existing method, measuring OEE is based on three main elements consisting availability, performance and quality. The purpose of this paper is to evaluate the recognized metrics of production: OEE and overall line effectiveness (OLE) by using smart systems techniques.

Design/methodology/approach
In this paper, to improve the calculative methods and productivity with three methods: measuring OEE using Mamdani fuzzy inference systems (FIS), measuring OEE using Sugeno FIS, and measuring OLE using FIS and artificial neural networks (ANNs) are proposed.

Findings
The proposed methodologies aim to decrease some weaknesses of OEE and OLE methods by exploiting intelligent system techniques, such as FIS and ANNs. In particular, this research will solve the following issues that occur in manual and automatic data gathering. This technique is an effective way of measuring OEE and OLE with regard to different weights of losses as well as difference in the weight of the machines. In addition, it allows the operator’s knowledge to take a part in the measurement using uncertain input and output with implementation of linguistic terms. The presented method is the details and capabilities of those methods in various tested scenarios, and the results have been fully analyzed.

Originality/value
In relation to other methodologies, it allows the operator’s knowledge to take part in the measurement using uncertain input and output with implementation of linguistic terms. The presented method is the details and capabilities of those methods in various tested scenarios, and the results have been fully analyzed.
A must for agencies or a candidate for deletion
Authors: Xie Sherry Li 
Published: January 2019

Purpose
This paper aims to report on a study that aimed at analyzing the relationships between information security and records management (RM), both as programs/functions established in organizations. Similar studies were not found in relevant literature.

Design/methodology/approach
The study used the classic grounded theory methodology. Pursuing the general curiosity about the information security-RM relationship in organizations, the study selected the United States (US) Federal Government as its field of entrance and followed the process of the classic grounded theory methodology that starts from the letting of the emergence of the research question to the formulation of a substantive theory that answered the question.

Findings
On the emergent question that why, despite the legislative establishment of agency RM programs and the use of the term records in their work, the US Federal Government information security community considered RM a candidate for deletion (CFD), the study coded the truncated application of the encompassing definition of records as the underlying reason. By this code, along with its three properties, i.e. limitations by the seemingly more encompassing coverage of information, insufficient legislative/regulatory support and the use of the terms of evidence and preservation in the records definition, the CFD consideration and the associated phenomena of unsound legislative/regulatory conceptualization, information shadow, information ignorance and archival shadow were explained.

Research limitations/implications
The study results suggested the data for subsequent theoretical sampling to be the operational situations of individual agency RM programs.

Practical implications
The rationale presented in the study regarding the encompassing nature of records and the comprehensive scope of RM program can be used for building strong RM business cases.

Originality/value
The study appears to be the first of its kind, which examined the RM–information security relationship in a very detailed setting.