bluuebunny/crossref_metadata_2025_split huggingface dataset:
Análise do Modelo de Negócio das Ventures Builders
Authors: Azevedo Ellen Maria Lopes , Silva Ana Cláudia Olegário da , May Márcia Ramos 
Published: April 2018

O objetivo deste estudo é analisar o modelo de negócio das ventures builders que apoiam o desenvolvimento das startups. Uma a cada quatro startups brasileiras encerram suas atividades em um ano e o percebido é que empreendedores têm dificuldades no acesso a fontes de financiamentos e conhecimento para novos negócios. Há estudos que discutem mecanismos de apoio a startups, como operações de venture capital e atuação de aceleradoras. Porém, são escassas as pesquisas que discutem o modelo de negócio das venture builders. O estudo tem abordagem qualitativa, com caso único, de natureza exploratória e descritiva. Os dados foram coletados por meio de entrevistas semiestruturadas e documentos. A técnica de análise adotada foi a análise de conteúdo com auxílio do software Atlas.ti. Os principais resultados encontrados foram nos quatro elementos do modelo de negócio da organização. Na proposição de valor, a venture builder cria valor ao seu cliente compartilhando conhecimento e disponibilizando recursos financeiros. Na fórmula de lucro, ao mesmo tempo em que a venture builder entrega valor para o cliente, cria valor para si, pois adquire participação societária da startup. Nos recursos-chave, as pessoas têm um papel essencial para o compartilhamento de conhecimento e o alcance das metas estipuladas. Por fim, o processo-chave envolve execução de serviços especializados e mentorias direcionadas. Assim, as principais características que diferenciam o modelo de negócio da venture builder analisada são o tempo de duração do processo, a execução dos serviços operacionais e o networking.
The personality types and psychological contract interaction to corporate reflection<p>Kişilik kuramları ve psikolojik sözleşme etkileşiminin işletmelere yansıması
Authors: Konakay Gönül , Çelik Faik 
Published: April 2018

Psychological contract try to bring light to the bottom of why their behavior and reactions. Those who are employed if examined in this different way can clarify expectations and it can be beneficial to social cohesion as to employment, productivity, trade. Human nature contains diverse and opposing forces. These are our racial heritage, the environmental conditions and the personal world over which one builds on them. These occurrences enter into each other over time and interact with the purposes of the operator.Karen Horney while the pathology of certain characters and character types, alienation, self-realization, true self, is extremely different interpretations of the concepts of traditional psychology ideal image and self-hatred. Karen Horney's path the use of energy and ideas to self-realization of man's and is passion to be perfect imposed that is ilness in our age, the disease is important for businesses. What should want the business running? Always and everywhere, "Is that perfect? Business and human relations are dealt again.This study examines the relationship between psychological contracts and personality types, and investigates the importance and weight of Karen Horney's personality analysis. It is aimed to solve the relation network methodologically.Extended English summary is in the end of Full Text PDF (TURKISH) file. ÖzetPsikolojik sözleşme çalışanların tavır, davranış ve tepkilerindeki dip nedenlere aydınlık getirmeye çalışmaktadır. İstihdam edilenlere bu farklı yaklaşım beklentileri netleştirebilecek ve de istihdama, verime, dış ticarete, toplumsal bütünlüğe fayda sağlayabilecektir. İnsan doğası çeşitli ve birbirine zıt güçleri ihtiva etmektedir. Bunlar ırsi mirasımız, çevresel koşullar ve zaman içinde kişinin bunların üstüne kendisinin oluşturduğu kişisel dünyadır. Bu oluşumlar zaman içinde birbiri ile içiçe girmekte ve işletmenin amaçlarıyla etkileşmektedir.Karen Horney’in insanın içsel enerjisinin kendini gerçekleştirme yolunda kullanılması konusunda ve çağımızda dayatılan mükemmel olma tutkusunu hastalık olarak görme fikirleri işletmeler için önemlidir. İşletmeler çalışanlarından ne istemelidir? Her zaman ve her yerde “mükemmel olmayı mı? İşletme ve insan ilişkisi yeniden ele alınmaktadır.Bu çalışma psikolojik sözleşme ile kişilik tipleri arasındaki ilişkiyi incelemekte, Karen Horneyin kişilik tahlilinin önemi ve ağırlığını araştırmaktadır. Metodolojik olarak ilişki ağını çözmek amaçlanmıştır.
Study of one-dimensional cure simulation applicable conditions for thick laminates and its comparison with three-dimensional simulation
Authors: Ren Mingfa , Wang Qi , Cong Jie , Chang Xin 
Published: April 2018

Abstract
The comparison of one- and three-dimensional cure simulation of thick thermoset matrix laminates was conducted in this study. The applicable conditions of one-dimensional cure simulation were investigated. The transient heat conduction equation coupled to the cure kinetics was solved numerically using one- and three-dimensional finite element analysis. The evolution of temperature and degree of cure of the laminates during the curing process obtained by the simulation agreed well with the published experimental results. The results indicate that a wider one-dimensional analysis applicable region around the center point will be obtained in the laminate with a higher span-to-thickness ratio and in a less anisotropic material system. In the applicable region, the accuracy of the one-dimensional cure simulation can satisfy the engineering request and save the computational cost. While beyond the region, there is a steep increase in deviation of the one- and three-dimensional simulation results.
Active Braking of Whole-Arm Reaching Movements Provides Single-Trial Neuromuscular Measures of Movement Cancellation
Authors: Atsma Jeroen , Maij Femke , Gu Chao , Medendorp W. Pieter , Corneil Brian D. 
Published: April 2018

Movement inhibition is an aspect of executive control that can be studied using the countermanding paradigm, wherein subjects try to cancel an impending movement following presentation of a stop signal. This paradigm permits estimation of the stop-signal reaction time or the time needed to respond to the stop signal. Numerous countermanding studies have examined fast, ballistic movements, such as saccades, even though many movements in daily life are not ballistic and can be stopped at any point during their trajectory. A benefit of studying the control of nonballistic movements is that antagonist muscle recruitment, which serves to actively brake a movement, presumably arises in response to the stop signal. Here, nine human participants (2 female) performed a center-out whole-arm reaching task with a countermanding component, while we recorded the activity of upper-limb muscles contributing to movement generation and braking. The data show a clear response on antagonist muscles to a stop signal, even for movements that have barely begun. As predicted, the timing of such antagonist recruitment relative to the stop signal covaried with conventional estimates of the stop-signal reaction time, both within and across subjects. The timing of antagonist muscle recruitment also attested to a rapid reprioritization of movement inhibition, with antagonist latencies decreasing across sequences consisting of repeated stop trials; such reprioritization also scaled with error magnitude. We conclude that antagonist muscle recruitment arises as a manifestation of a stopping process, providing a novel, accessible, and within-trial measure of the stop-signal reaction time.SIGNIFICANCE STATEMENTThe countermanding or stop-signal paradigm permits estimation of how quickly subjects cancel an impending movement. Traditionally, this paradigm has been studied using simple movements, such as saccadic eye movements or button presses. Here, by measuring upper limb muscle activity while human subjects countermand whole-arm reaching movements, we show that movement cancellation often involves prominent recruitment of antagonist muscles that serves to actively brake the movement, even on movements that have barely begun. The timing of antagonist muscle recruitment correlates with traditional estimates of movement cancellation. Because they can be detected on a single-trial basis, muscle-based measures may provide a new way of characterizing movement cancellation at an unprecedented within-trial resolution.
Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking
Authors: Parrilla-Carrero Jeffrey , Buchta William C. , Goswamee Priyodarshan , Culver Oliver , McKendrick Greer , Harlan Benjamin , Moutal Aubin , Penrod Rachel , Lauer Abigail , Ramakrishnan Viswanathan , Khanna Rajesh , Kalivas Peter , Riegel Arthur C. 
Published: April 2018

Cocaine addicts display increased sensitivity to drug-associated cues, due in part to changes in the prelimbic prefrontal cortex (PL-PFC). The cellular mechanisms underlying cue-induced reinstatement of cocaine seeking remain unknown. Reinforcement learning for addictive drugs may produce persistent maladaptations in intrinsic excitability within sparse subsets of PFC pyramidal neurons. Using a model of relapse in male rats, we sampled >600 neurons to examine spike frequency adaptation (SFA) and afterhyperpolarizations (AHPs), two systems that attenuate low-frequency inputs to regulate neuronal synchronization. We observed that training to self-administer cocaine or nondrug (sucrose) reinforcers decreased SFA and AHPs in a subpopulation of PL-PFC neurons. Only with cocaine did the resulting hyperexcitability persist through extinction training and increase during reinstatement. In neurons with intact SFA, dopamine enhanced excitability by inhibiting Kv7 potassium channels that mediate SFA. However, dopamine effects were occluded in neurons from cocaine-experienced rats, where SFA and AHPs were reduced. Pharmacological stabilization of Kv7 channels with retigabine restored SFA and Kv7 channel function in neuroadapted cells. When microinjected bilaterally into the PL-PFC 10 min before reinstatement testing, retigabine reduced cue-induced reinstatement of cocaine seeking. Last, using cFos-GFP transgenic rats, we found that the loss of SFA correlated with the expression of cFos-GFP following both extinction and re-exposure to drug-associated cues. Together, these data suggest that cocaine self-administration desensitizes inhibitory Kv7 channels in a subpopulation of PL-PFC neurons. This subpopulation of neurons may represent a persistent neural ensemble responsible for driving drug seeking in response to cues.SIGNIFICANCE STATEMENTLong after the cessation of drug use, cues associated with cocaine still elicit drug-seeking behavior, in part by activation of the prelimbic prefrontal cortex (PL-PFC). The underlying cellular mechanisms governing these activated neurons remain unclear. Using a rat model of relapse to cocaine seeking, we identified a population of PL-PFC neurons that become hyperexcitable following chronic cocaine self-administration. These neurons show persistent loss of spike frequency adaptation, reduced afterhyperpolarizations, decreased sensitivity to dopamine, and reduced Kv7 channel-mediated inhibition. Stabilization of Kv7 channel function with retigabine normalized neuronal excitability, restored Kv7 channel currents, and reduced drug-seeking behavior when administered into the PL-PFC before reinstatement. These data highlight a persistent adaptation in a subset of PL-PFC neurons that may contribute to relapse vulnerability.
Differential Expression of Histone H3.3 Genes and Their Role in Modulating Temperature Stress Response inCaenorhabditis elegans
Authors: Delaney Kamila , Mailler Jonathan , Wenda Joanna M , Gabus Caroline , Steiner Florian A 
Published: April 2018

AbstractHistone H3.3, a major variant of canonical histone H3, is highly conserved and essential for viability or fertility in most lineages. In Caenorhabditis elegans, H3.3 is expressed from five genes. Here, Delaney...Replication-independent variant histones replace canonical histones in nucleosomes and act as important regulators of chromatin function. H3.3 is a major variant of histone H3 that is remarkably conserved across taxa and is distinguished from canonical H3 by just four key amino acids. Most genomes contain two or more genes expressing H3.3, and complete loss of the protein usually causes sterility or embryonic lethality. Here, we investigate the developmental expression patterns of the five Caenorhabditis elegans H3.3 homologs and identify two previously uncharacterized homologs to be restricted to the germ line. Despite these specific expression patterns, we find that neither loss of individual H3.3 homologs nor the knockout of all five H3.3-coding genes causes sterility or lethality. However, we demonstrate an essential role for the conserved histone chaperone HIRA in the nucleosomal loading of all H3.3 variants. This requirement can be bypassed by mutation of the H3.3-specific residues to those found in H3. While even removal of all H3.3 homologs does not result in lethality, it leads to reduced fertility and viability in response to high-temperature stress. Thus, our results show that H3.3 is nonessential in C. elegans but is critical for ensuring adequate response to stress.
Primary leiomyosarcoma of kidney with metastasis to contralateral kidney. Case report
Authors: Vasquez Ciriaco Sergio , García Espinoza Jaime Aron , Garcia Pedro Elena Enselmini 
Published: April 2018

Introduction
Renal leiomyosarcoma is a rare entity in the world and its understanding is based on reports and various cases; however, the prognosis is bleak for its malignant potential and an average survival of 18 months.

Clinical case
A 54-year-old woman with a clinical picture of 6 months of pain in the right flank and a tomographic image of a bilateral renal lesion underwent right radical nephrectomy and left conservative surgery. The definitive histopathological study reported right primary renal leiomyosarcoma with left metastasis.

Conclusion
Renal leiomyosarcoma is an entity of low incidence and high mortality; however, our case represents the minority of patients with contralateral kidney metastasis reported in the literature.
Una escuela secundaria posible
Authors: Ferreyra Horacio Ademar 
Published: April 2018

La presente investigación expone los rasgos de lo que se define como escuela posible, los ejes que la conforman ―sentido, contexto, evolución― y las dimensiones que abarca cada uno de estos: currículum, saberes y prácticas, trayectorias de los estudiantes, clima y ambiente institucional, desarrollo profesional docente y relaciones con las familias y la comunidad. Articula, además, esos componentes alrededor del eje de la gestión escolar y aporta nuevas perspectivas para comprender los procesos que desenvuelve la escuela secundaria para su construcción de calidad. Como conclusión de puede decir que una escuela posible presupone la existencia de alternativas plausibles que anuncian propuestas de cambio. Una educación de calidad, dentro de una escuela posible, constituye un nuevo espacio de encuentro, hacia un horizonte anhelado que Paulo Freire denomina el inédito viable. Este artículo tiene la intencionalidad de contribuir al debate educativo actual en torno a la temática.
Grafik Tasarım Programı Öğrencilerinin Ders Başarı Düzeylerinin Mezun Oldukları Liselere Göre Değerlendirilmesi
Authors: Ayçe Mehmet Taragay , Sevindik Orhan 
Published: April 2018

Bu
çalışmada meslek yüksekokulu Grafik Tasarım programı öğrencilerinin bölüm derslerindeki
başarı düzeyleri, mezun oldukları lise türleri göz önüne alınarak
incelenmiştir. Çalışma, İstanbul Arel Üniversitesi Meslek Yüksekokulu Grafik
Tasarım programı öğrencileri temel alınarak yapılmıştır. Yöntem olarak
öğrenciler, mezun oldukları liselere göre gruplandırılmış ve üniversite
eğitimlerinde seçilen derslere göre başarı durumları incelenmiştir.
Veriler, çeşitli istatistik yöntemleri
kullanılarak analiz edilmiştir. Grafik Tasarım programındaki dersler
incelendiğinde mezun olunan derslere göre başarı düzeylerinin değişkenlik
gösterdiği görülmüştür.
EFFECT of IONIC LIQUID CONTENT on MONOLITHIC STRUCTURE of AMINE-MEDIATED SILICA AEROGEL via AMBIENT PRESSURE DRYING
Authors: GİZLİ Nilay , SERT ÇOK Selay , KOÇ Fatoş 
Published: April 2018

In
this study, amine-mediated silica aerogels dried under the ambient conditions
in monolithic form were prepared by following sol-gel method.
3-aminopropyltriethoxysilane (APTES) was involved to the synthesis as a silica
co-precursor. Imidazolium based short-chain ionic liquids (ILs) were
incorporated into the silica gel structure to control the gel shrinkage within
the pores, as well as to eliminate the capillary effect during the solvent
evaporation. A production procedure was developed to explore the synergistic
effect of ionic liquids and amine functionalized silica precursor on the
textural and chemical properties of the final silica gels. Surface
modifications of the samples were performed by using
3-Methacryloxypropyltrimethoxysilane (MEMO) to ensure hydrophobic
characteristics. To reveal the chemical and morphological characteristics of
the resultant material, various analyses were conducted. SEM and FTIR analyses were performed to
investigate the morphological and chemical structure, whereas TGA analysis was
carried out to determine the thermal stability of the silica gels. As a result,
ionic liquid embedded sample was obtained in a monolithic structure with a low
density (0.45 g/cm3) and had a good thermal stability (up to 381 °C). Contact
angle measurement also demonstrated that the desired monolithic sample has
hydrophobic characteristic with a water contact angle value of 113˚.
O ENSINO DA DIVERSIDADE ÉTNICO-RACIAL NA ESCOLABÁSICA: UM RELATO DE EXPERIÊNCIA VIVIDA NO PROGRAMA INSTITUCIONAL DE BOLSA DE INICIAÇÃO À DOCÊNCIA (PIBID)
Authors: Nascimento Rafael Baioni , Amorim Monica Maria Teixeira 
Published: April 2018

Resumo: Este relato resulta da experiência vivida no PIBID de Pedagogia da Universidade Estadual de Montes Claros. O trabalho realizado consistiu em um projeto de ensino que foi desenvolvido por um grupo de acadêmicas do citado curso com uma turma de crianças do 1º ano do ensino fundamental. A problemática que desencadeou o trabalho tem sua origem em estudo teórico que realizou-se com as acadêmicas sobre o tema diversidade, identidade e educação das relações raciais. Esse estudo, aliado a diagnóstico realizado com as crianças, suscitou a reflexão sobre o papel da escola na formação de subjetividades e sobre a importância do currículo escolar contemplar a diversidade étnico-racial. Assim, desenvolveu-se um projeto de ensino que teve como objetivo geral contribuir para a melhoria da autoestima das criançasa partir do reconhecimento da diversidade, da sua identidade cultural e suas características físicas. O projeto foi realizado ao longo de um mês com um encontro por semana. A metodologia adotada envolveu aulas dialogadas, rodas de conversa e de discussão, sessão de história e análise de imagens. A experiência vivida indica a relevância do PIBID enquanto espaço para potencializar a formação das graduandas e a implementação da Lei 10.639 na escola básica.Palavras chave:Ensino da História, Diversidadeétnico-racial, Escola Básica.
ORYANTALİST BAKIŞ AÇISININ SİNEMAYA YANSIMASI: THE PHYSCIAN (2013) FİLMİ ÖRNEĞİ
Authors: SATIR Mehmet Emin , Özer Nuri Paşa 
Published: April 2018

Doğu bilimi ya da
şarkiyatçılık olarak da bilinen oryantalizm, her ne kadar Doğu kültürlerini ve
dillerini tanımak için kurulmuş akademik bir disiplin olsa da içerisinde
iktidar ilişkilerini de barındırmaktadır. Edward Said’in betimlediği üzere
oryantalizm, Batı dünyasının Doğu dünyası üzerinde hegemonya kurabilmesini kolaylaştıran
ve ön yargılardan beslenen bir düşünce sistemidir. Batı’nın kurgulamış olduğu
Doğu imajı olarak da görülen oryantalizm, çok eski dönemlerden beri kendisini
birçok alanda göstermektedir. Edebiyattan müziğe, resimden mimariye kadar
birçok farklı alanda varlık gösteren oryantalist bakış açısının izlerine
sinemada da rastlanılmaktadır. Sinema, sanat formu olmasının yanı sıra bir
kitle iletişim aracıdır ve toplumsal bir özelliğe sahiptir. Dolayısıyla sinema ve toplumsal yaşam
arasında kuvvetli bir bağ bulunmaktadır. Hem görsel hem de işitsel unsurların
etkili şekilde kullanılabildiği sinema aracılığıyla oryantalist bakış açısı,
toplumsal düzlemde yeniden üretilebilmektedir. Oryantalist bakış açısının
sinemada birçok örneği bulunmaktadır. The Physician (2013) filmi, bu örneklerin
bir tanesidir. The Physician, 2013 yılında Philipp Stölzl tarafından
yönetilmiş, dram/tarih türünde bir filmdir. Film, Rob Cole isimli karakterin,
İbn-i Sina’dan tıp eğitimi almak için Londra’dan İsfahan’a yaptığı yolculuğu ve
sonrasında gelişen olayları anlatmaktadır. Film genelinde oryantalist öğelere
sıkça rastlanılmaktadır, bu bağlamda yapılmış olan çalışmanın amacı, The
Physician (2013) filminde yer alan oryantalist öğeleri, içerik analizi
yöntemiyle ortaya çıkartmaktır.
Factors that Affect Mother to the Children (2-36 month) Exclusion in Sub PIN Diphtheria
Authors: Swardana Nicholas Fransida , Wahjuni Chatarina Umbul 
Published: April 2018

ABSTRACTSub National Immunization Week (PIN) Diphtheria is an additional immunization activity simultaneously in 19 regencies/ cities as an attempt to cope with outbreak of diphtheria in East Java. Sub PIN Diphtheria coverage result in 2012 in the Sukolilo Village, Surabaya in children(2–36 months) did not fulfill the target because there are many children(2–36 months) that did not participate. This study was conducted to analyze the factors that affect mother to the children(2–36 months) exclusion in Sub PIN Diphtheria in the Sukolilo Village, Surabaya 2013, include: maternal age, maternal education level, maternal employment, number of children, mother’s level of knowledge, maternal attitudes, husband support, community support, and exposure information. This study conducted with observational analytic approach and case control design. Large sample of 90 mothers drawn by simple random sampling. Statistical analysis is used multiple logistic regression with α < 0.05. The results showed that the variables that affect the exclusion of mothers to immunize children(2–36 months) in Sub PIN Diphtheria sequentially are less maternal attitude (p = 0.000), maternal less knowledge (p = 0.005), the husband does not support (p = 0.047), and were not informed (p = 0.018). Whereas maternal age, maternal education level, maternal employment, number of children, and the community support has no effect because the p value < 0.05. Therefore it is necessary counseling and motivation to the mother, socialization to the husband, and optimize health promotion media in order to minimize the exclusion Sub PIN Diphtheria future.Keywords: children (2–36 months), diphteria, immunization, knowledge, attitude