bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study to evaluate the prognostic significance of thrombocytopenia among critically ill children
Authors: Mundkur Suneel C. , Upadhyay Ranjani , Hebbar Shrikiran A. , Kini Pushpa , Bhaskarananda Nalini , Shashidhara Sowmya 
Published: January 2019

Background: Pediatric critical care differs from Adult critical care not only in age but also in the outcomes. There are no studies regarding thrombocytopenia in the pediatric population. Therefore, in the current study, our objective was to study the prevalence and, the severity of thrombocytopenia, clinical features, and prognostic significance of low platelet count as an independent predictor of mortality and prolonged hospital and ICU stay.Methods: This was a prospective observational study conducted at tertiary care paediatric intensive care unit in India. Children between 1 month to 18 years admitted to the Pediatrics intensive care unit with thrombocytopenia due to any cause at admission were involved in the study. Detailed history was documented. Haemoglobin levels, total leucocyte counts, platelet counts, and platelet indices were recorded on the first and fourth day of admission. Outcomes were analysed in term of survivors and non-survivors and duration of ICU and hospital stay.Results: The study group consisted of 150 children with mean age of 8.458(± 5.604) years. Majority of children in the study group had severe thrombocytopenia 77 (51.3%). Moderate and mild thrombocytopenia was seen in 35(23.3%) and 38(25.4%) children respectively. Infection (50.66%) was the most common cause of thrombocytopenia, followed by sepsis (10.66%). Sepsis (27.5%) was observed to be the most common cause of mortality. Rise in platelet count on the fourth day among survivors, and no survivors were observed in 79.1% and 15.9% respectively. Failure of the rise in platelet count on the fourth day of admission was significantly associated with mortality (p value=0.001). The severity of thrombocytopenia does not correlate with duration of hospital and ICU stay.Conclusions: Platelet counts and indices at the time of admission to a critical care unit have limited use as a prognostic marker for predicting mortality in children.
Ankle brachial index measurement in first-line health care: A simple and inexpensive but very valuable method
Authors: AKBULUT Birkan 
Published: January 2019

Aim: Peripheral arterial disease (PAD) affects more than 30 million
people in the World. Ankle Brachial Index (ABI) is a simple method to detect
PAD. Patients are referred to vascular surgery department with prediagnosis of
PAD, but many of them are mis-diagnosed. The aim of this study was to determine
the importance of ABI in first-line health care. Material and Methods: From December 2017 –
November 2018; 108 patients were
referred from first-line health care units to our department. Patients were
analyzed retrospectively regarding risk factors, ABI and real diagnosis. Results: 24 patients (22,22%) were diagnosed PAD. Mean ABI in PAD
and non-PAD patients was 0.545±0.193 and 0.996±0.093, respectively.

Conclusion: The use of ABI
measurement in first-line health care could avoid the mis-diagnosis of PAD and
related loss of time and additional costs.
The prognostic role of fragmented QRS complex in acute myocarditis
Authors: ÜNAL Sefa , YİLMAZ Samet , YAYLA Çağrı , KUYUMCU Mevlüt Serdar , ERBAY İlke , AÇAR Burak , KARANFİL Mustafa , ERTEM Ahmet Göktuğ , DEMİRTAŞ Koray , AKDİ Ahmet , AYDOĞDU Sinan 
Published: January 2019

Aim:
Although
a fulminant course of the myocarditis is difficult to predict, it may lead to
acute heart failure and death. Previous studies have demonstrated that reduced
left ventricular systolic function and prolonged QRS duration can predict the
fulminant course. This study aimed to identify whether fragmented QRS complex
(fQRS) could also be predictive of fulminant disease in this population. Material and Methods: We retrospectively included 156 patients diagnosed with acute
myocarditis. They were divided into the fulminant group (n = 18) and the
non-fulminant group (n = 138). Multivariate logistic regression analysis was
used to identify the independent factors predictive of fulminant disease. Results: Fragmented
QRS developed in 11 (61%) in the fulminant group and only 10 patients (7%) in
the non-fulminant group (p &lt;0.001). Patients with fulminant myocarditis had a higher mortality rate
than those with non-fulminant disease (44.6% vs. 0%, p &lt; 0.001).
Multivariate analysis revealed that the presence of fQRS (p=0.019), longer
Tpe/qt ratio (p=0.022) and clinical heart failure (&lt;0.001) were significant predictors associated with a fulminant course
of myocarditis.

Conclusion:
The presence of fQRS complex, as a simple and feasible
electrocardiographic marker, seems to be a novel predictor fulminant
myocarditis. This
simpleparameter may be used in identifying patients at high risk for fulminancy
and so early mechanical support could provide
improved patient outcomes.
Analysis of myocardial texture in patients with isolated left ventricular noncompaction
Authors: ÜNAL Sefa , AÇAR Burak , YAYLA Çağrı , ERTEM Ahmet Göktuğ , TÜFEKÇİOĞLU Omaç , ARAS Dursun 
Published: January 2019

Aim: Videodensitometric myocardial texture analysis (VMTA)
has been widely used to investigate left ventricular (LV) dysfunction in
various cardiac disorders. Patients with isolated left ventricular
noncompaction (IVNC) experience an undulating decline in LV function. The aim of
this study was to assess the value of VMTA for evaluating deterioration of LV function in this patient group.Material
and Methods: Twenty-two patients with IVNC (10 asymptomatic
[preserved LV function], 12 symptomatic [LV dysfunction]) and 12 healthy
controls were evaluated. Videodensitometry was used to record background-corrected mean gray levels
(BC-MGL) for 2 regions of the mid-basal LV wall (the interventricular
septum [IVS] and the posterior wall [PW]) at end-systole and end-diastole. The
cyclic variation (CV) index for each region was calculated according to the
formula, CV index % = ([BC-MGLend-diastole – BC-MGLend-systole]
÷ BC-MGLend-diastole) × 100. Results:
The mean IVS-CV index in the symptomatic IVNC group (12.3 ± 4.9%) was significantly lower than the
corresponding findings in the asymptomatic IVNC group (32.3 ± 14.8%,
p &lt; 0.05) and control group (36.6 ± 12.1%, p &lt; 0.001). The mean PW-CV
index in the symptomatic group (15.1 ± 5.5%) was also significantly
lower than the corresponding values in the asymptomatic (27.0 ± 10.4%,
p &lt; 0.05) and
control groups (28.8 ± 10.9%, p &lt; 0.001).

Conclusion: VMTA is a practical, useful adjunct to conventional echocardiography for assessing LV
myocardium in patients with IVNC. Detection of reduced CV index values might
predict the early stages of LV deterioration in this group.
PENDIDIKAN KARAKTER DI KELUARGA
Authors: Zainuri Ahmad 
Published: January 2019

Family is the first and foremost environment for a human child. In the family a child is raised, learns the ways of association that he will develop later in the social life environment that is outside the family. In simple terms it can be argued that the function of the family is to stabilize the family situation in the sense of stabilizing the family's economic situation. Then the family functions also educate and maintain the physical and psychological family, including religious life.
Here the role of parents, especially mothers, is very influential on the development of the child. Family education is called primary education because in this environment all human potential is formed and partially developed. There are even some potentials that have developed in family education. Children will grow up to be characterless individuals if they can grow in a characteristic environment, so that the nature of every child born holy can develop optimally. Character education must start from the family to build a noble national personality. To achieve the child's character expected by parents, parenting given by the family to children is closely related to the character of the child in his growth and development. These characters will be carried to adulthood even if they form their own family.
On the contrary, family failure in shaping children's character will result in the growth of a society that has no character. Therefore, every family must have an awareness that the formation of children's character is very dependent on character education at home. Furthermore, Megawangi (2003) mentions that there are at least three basic children's needs that must be met, namely maternal bonding, security, and physical and mental stimulation
“Menos política, mais eficiência”: uma análise sociológica das práticas de auditoria e produção de sentidos morais no campo burocrático
Authors: Brito Simone Magalhães 
Published: January 2019

O objetivo desse artigo é discutir a experiência moral de auditores e os valores que organizam as práticas de auditoria para compreender, especificamente, como esses valores – centrados no ideal de transparência – informam ou pretendem afetar as disputas na elite do campo burocrático. A pesquisa é de natureza qualitativa, baseada em 17 entrevistas, com auditores de um órgão de controle interno (o Ministério da Transparência e Controladoria-Geral da União-CGU), sobre as políticas de transparência e suas experiências cotidianas de combate aos desvios.
Entre o cuidado e a medicamentalização: os debates sobre “trocar uma droga por outra”
Authors: Vargas Annabelle de Fátima Modesto , Campos Mauro Macedo 
Published: January 2019

Este artigo resulta de uma pesquisa realizada em um CAPSad (Centro de Atenção Psicossocial Álcool e Drogas) do Estado do Rio de Janeiro. Foi investigada a operacionalização das políticas públicas de saúde mental, álcool e outras drogas, a partir de seus operadores, os “burocratas de nível de rua”. Busca-se compreender como se efetiva a utilização de medicamentos psiquiátricos no CAPSad, a partir da relação imbricada entre as drogas lícitas e ilícitas. Trata-se de uma pesquisa qualitativa, construída através de observação participante, anotações em diário de campo e entrevistas em profundidade. Os achados no campo de pesquisa apontam para uma incômoda e crescente medicamentalização. A operacionalização do trabalho está fortemente centrada na utilização de medicamentos, relegando o uso das tecnologias leves a um plano de cuidado complementar e não principal.
A Clinical Investigation about Horizontal Heterophoria Among Newly Diagnosed Myopia Juveniles in Nanchong District of China
Authors: Yan Ying Li , Li Long , Wang Ying , Zeng Peng Guan , Zou Chun Yun 
Published: January 2019

Abstract
Background: To establish the prevalence and distribution of heterophoria in low myopia juveniles and and provide evidence of myopia prevention and treatment.
Methods: Near and distant heterophoria were administered to the patients who were diagnosed of low myopia at their first visit in clinic. Tthe Von Graefe method was performed to test near, distant horizontal heterophoria types and degrees. Statistical analysis was performed with SPSS17.0 software.
Results: A total of 150 students were participated in this study. Distant and near phoria was detected in 92.67% and 96.00% of the students respectively. exophoria was more common than esophoria(diantant:79.33% vs 13.33%; near:86.67% vs 9.33%, P<0.05), and the mean deviation of diantant and near heterophoria was -1.97△ and -3.91△. There was a statistical difference between the near and distant heterophoria (P<0.05).
Conclusions: Most myopia juveniles have different extents of exophoria. Due to the high prevalence of heterophoria in myopia, in the process of refraction, attention should be paid to the examination of binocular visual function parameters such as heterophoria, which is conducive to the issuance of suitable optical correction prescriptions and the reasonable measures for myopia prevention and control.
Keywords: Heterophoria, myopia, juvenile school students
Evaluation of an instantaneous dryness index-based calibration-free continuous hydrological model in India
Authors: Patnaik Swagat , Sharma Vimal Chandra , Biswal Basudev 
Published: January 2019

AbstractTraditional continuous hydrological models have a large number of free parameters whose values need to be determined through calibration, and thus their applicability is limited to gauged basins. For prediction in ungauged catchments, hydrologists generally follow regionalization methods to develop region-specific calibration-free continuous models. An alternative attempt was made recently to develop a calibration-free model by proposing an empirically derived universal ‘decay function’ that enables definition of instantaneous dryness index as a function of antecedent rainfall and solar energy. The model was earlier tested in the USA, and its performance was found to be comparable to that shown by regionalization-based models. Here, we test the instantaneous dryness index-based calibration-free model considering data from 108 Indian catchments. The medians of coefficient of determination (R2), Nash–Sutcliffe efficiency (NSE) and Kling–Gupta efficiency (KGE) values for the study catchments, respectively, are 0.50, 0.38 and 0.40. Furthermore, the model's performance significantly improved upon Box–Cox transformation (RBC2, NSEBC and KGEBC, respectively, are 0.70, 0.52 and 0.57), suggesting that the model predicts discharge quite well except during flood periods. Overall, our results suggest the model can be used as an alternative platform for predicting discharge in ungauged catchments in the USA and peninsular India, if not in every part of the world.
Assessment of clogging in constructed wetlands by saturated hydraulic conductivity measurements
Authors: Licciardello F. , Aiello R. , Alagna V. , Iovino M. , Ventura D. , Cirelli G. L. 
Published: January 2019

Abstract
This study aims at defining a methodology to evaluate Ks reductions of gravel material constituting constructed wetland (CW) bed matrices. Several schemes and equations for the Lefranc's test were compared by using different gravel sizes and at multiple spatial scales. The falling-head test method was implemented by using two steel permeameters: one impervious (IMP) and one pervious (P) on one side. At laboratory scale, mean K values for a small size gravel (8–15 × 10−2 m) measured by the IMP and the P permeameters were equal to 19,466 m/d and 30,662 m/d, respectively. Mean Ks values for a big size gravel (10–25 × 10−2 m) measured by the IMP and the P permeameters were equal to 12,135 m/d and 20,866 m/d, respectively. Comparison of Ks values obtained by the two permeameters at laboratory scale as well as a sensitivity analysis and a calibration, lead to the modification of the standpipe equation, to evaluate also the temporal variation of the horizontal Ks. In particular, both permeameters allow the evaluation of the Ks decreasing after 4 years-operation and 1–1.5 years' operation of the plants at full scale (filled with the small size gravel) and at pilot scale (filled with the big size gravel), respectively.
The leakage of sewer systems and the impact on the ‘black and odorous water bodies’ and WWTPs in China
Authors: Cao Y. S. , Tang J. G. , Henze M. , Yang X. P. , Gan Y. P. , Li J. , Kroiss H. , van Loosdrecht M. C. M. , Zhang Y. , Daigger G. T. 
Published: January 2019

AbstractChina has achieved significant progress on wastewater treatment and aquatic environmental protection. However, leakage (in- and exfiltration) of sewer systems is still an issue. By using the statistical data of water and wastewater in 2016 in China, and the person loads (PLs) of water and wastewater in Singapore, the leakage fractions of hydraulic flow, organic carbon (COD), nitrogen (N) and phosphorus (P) mass loading, and in-sewer COD biological removal in the sewer systems of China (except Hong Kong, Macau and Taiwan), Shanghai, Guangzhou and Beijing were reported for the first time. The fractions of hydraulic flow infiltration (13%, Shanghai and Guangzhou) and exfiltration (39%, China) were calculated. Except Beijing, whose sewer networks are under appropriate management with small leakage fractions, the exfiltration fractions of COD (including in-sewer biological COD removal) ranged from 41% (Shanghai) to 66% (China) and averaged 55%; N ranged from 18% (Shanghai) to 48% (China) and averaged 33%; and P ranged from 23% (Shanghai and Guangzhou) to 44% (China) and averaged 30%. The exfiltrated sewage, COD, N and P not only wastes resources, but also contaminates the aquatic environment (especially groundwater) and contributes to ‘black and odorous water bodies’. In- and exfiltration in the sewer network leads to low influent COD concentration, C/N ratio and high inorganic solids and inert particulate COD concentrations of many municipal wastewater treatment plants (WWTPs) causing high cost for nutrient removal, poor resource recovery, additional reactor/settler volume requirement and other operational problems. Therefore, tackling sewer leakage is of primary importance to today's environment in China. Recommendations for the inspection of sewer systems and the rehabilitation of damaged sewers as well as the development of design and operation guidelines of municipal WWTPs tailored to the specific local sewage characteristics and other conditions are proposed.
Currículo educacional: algumas ponderações de professores
Authors: Braga Lucimar Araujo , Pereira Ana Lúcia 
Published: January 2019

Resumo: Neste trabalho, tivemos como objetivo apresentar e discutir o entendimento sobre currículo para professores em atuação nos cursos[1] de Letras da Universidade Estadual de Ponta Grossa (UEPG). Pelo viés da teoria crítica, investigamos o posicionamento de professores que atuam nestes cursos de licenciaturas formando professores para a educação básica. Metodologicamente, a pesquisa de cunho qualitativo se desenvolveu pela Análise Textual Discursiva e, como conclusão, percebemos que é preciso haver mais envolvimento de professores com os currículos das instituições em que atuam. [1] A Universidade Estadual de Ponta Grossa oferece os cursos de Letras Português-Francês; Português-Espanhol e Português-Inglês, cada um como curso independente.
Niveles de cortisol, desgaste profesional y satisfacción laboral en empleados universitarios
Authors: Ortiz Juan , Vega-Michel Claudia 
Published: January 2019

La relación psicológica de la gente con su trabajo, se puede conceptualizar como un continuo entre experiencias negativas de desgaste profesional (burnout) y las positivas de entusiasmo laboral (engagement), como un estado opuesto al desgate profesional o relación positiva con el trabajo. Se utilizó un estudio ex post facto retrospectivo para explorar y medir la relación entre el desgaste profesional, el entusiasmo laboral, con niveles de cortisol para evaluar el estrés y reclamo de gastos médicos en empleados universitarios. Participaron 199 sujetos. Se encontró una correlación positiva baja entre el factor de desgaste emocional y los niveles de cortisol, y una negativa entre síntomas y niveles de cortisol. No se encontraron diferencias en desgaste profesional y niveles de cortisol entre los sujetos que reclaman servicios de salud y los que no lo hacen, tampoco entre reclamos de los servicios de salud con los factores del desgaste profesional y niveles de cortisol. Se concluye que los bajos niveles de cortisol podrían estar relacionados con los niveles de entusiasmo laboral y tendrían relación con los bajos niveles de desgaste profesional. Se sugiere que las organizacionales, además de las habilidades administrativas, pongan atención a factores de estructura organizacional, el rediseño de actividades y el desarrollo de competencias para la vida.
Estrés parental, interacciones diádicas al comer y desnutrición en el periodo de alimentación complementaria
Authors: Cortés Moreno Assol , Méndez Lozano Sergio Manuel 
Published: January 2019

Este estudio tuvo como propósito evaluar el papel del estrés de la crianza y las interacciones madre-hijo en el estado de nutrición de una muestra de infantes. Participaron 20 niños eutróficos y 40 desnutridos, entre 6 y 18 meses de edad, y sus cuidadores: 27 díadas provenían de zona urbana y 33 de suburbana marginal. Se evaluó el estrés de la crianza empleando el Índice de Estrés Parental de Abidin (IEP). Se registraron en video las interacciones diádicas durante la comida para analizar el tipo de conductas maternas e infantiles recurrentes. Las madres de niños desnutridos puntuaron más alto que las de eutróficos en las subescalas del IEP de adaptabilidad, aceptabilidad y apoyo del cónyuge; sus interacciones se caracterizaron por negligencia y la falta de entusiasmo. El IEP correlacionó positivamente con la falta de entusiasmo y negativamente con el afecto positivo; la subescala de depresión se asoció positivamente con el puntaje total del IEP. Se subraya la importancia de evaluar una intervención basada en los estilos interactivos para modificar el estado de nutrición del niño y evaluar el efecto de tal modificación en estrés parental.
Uji Potensi Perlekatan Bakteri Asam Laktat Isolat TLA-15 Dan TLA-20 Pada Sel Epitel Usus Tikus (Rattus norvegicus)
Authors: Wijayanti Ernanin Dyah , Ardyati Tri 
Published: January 2019

In Vitro probiotic potential test that had been conducted before, which consist of probiotic bacteria test resistance toward the gastro-intestinal track pH and the bile salt concentration shows that the strain bacteria TLA-15 and TLA-20 had potential as probiotic bacteria. An advance test are required to fullfill the requirement as the probiotic bacteria. So that, the objective of this research are to study the viability of lactic acid bacteria strain TLA-15 and TLA-20 at the Rattus norvegicus GI track. At the first step of this research was added 4 106 cell/ml lactic acid bacteria TLA-15 and TLA-20 given orally.
EFEK PEMACUAN APOPTOSIS FRAKSI ETIL ASETAT EKSTRAK ETANOL AKAR PASAK BUMI (Eurycoma longifolia Jack) TERHADAP SEL HeLa
Authors: Nurkhasan Isnaniati Romadhoni Indarwati 
Published: January 2019

Pasak bumi is one of the Indonesian original plants having anticancer activity. Eurycomanone was isolated from Eurycoma longofolia, Jack root was proven to have cytotoxic effect and induce apoptosis on Hela cells. The objective this study was to know the cytotoxic activity of ethyl acetate fraction of ethanolic extract of the Eurycoma longifolia, Jack root on Hela cells and the mode of death. Ethyl acetate fraction was obtained from the ethyl acetate soluble fraction from residue of chloroform fraction of ethanolic extract of Eurycoma longifolia Jack roots. The cytotoxic assay was performed using MTT test method with concentration series used in this study were 1000; 750; 500; 400; 200; 100; 50; 12,5; 6,25; 3,125; and 1,5625 µg/ml. Absorbance was measured at wavelength of 550 nm using ELISA reader. Apoptosis assay were observed using Giemsa staining. MTT assay indicated that etil asetat fraction of ethanolic extract of the Eurycoma longofolia, Jack root showed cytotoxic activity againts Hela cells with IC50 value 3,70 µg/ml. The result of apoptosis assay indicated that the ethyl acetate fraction of ethanolic extract of the Eurycoma longofolia, Jack root induce apoptosis. The apoptotic cells was observed wrinkle, rounded and dark colors leading to chromatin condensation.