bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peranan Kompetensi Dalam Meningkatkan Kinerja Karyawan PT. Summit Oto Finance
Authors: Bahasoan Shandra 
Published: August 2019

The study was conducted aimed at knowing the role of competencies, namely knowledge, skills and self-concept in improving the performance of employees of PT. Summit Oto Finance, with a sample of 54 people . The method used in this study using questionnaires, interviews and documentation. Research approach by using quantitative descriptive method by analyzing Multiple Linear Regression to measure the performance of employees of PT. Summit Oto Finance. The results of this study simultaneously independent competency variables consisting of knowledge, skills and self-concept have a positive and significant influence on the dependent variable,namely employee performance. From the test results the correlation of the influence of competencies on employee performance is 94.1 percent while 5.9 percent is influenced by other factors. Dominant competencies affect the performance of employees of PT. Summit Oto Finance is a skill.
Terapia Ocupacional en Costa Rica: historia, evolución y retos futuros en la formación profesional
Authors: Valdelomar Marín Erick , Parra Montañez Ginna 
Published: August 2019

La Terapia Ocupacional (TO) como carrera socio sanitaria, centrada en el ser humano, se ocupa de promover la salud y el bienestar a través de la ocupación, cuyo objetivo principal es permitir que las personas participen en las actividades de la vida cotidiana (ocupaciones) a lo largo del ciclo de vida. La TO ha adquirido a través del tiempo un rol preponderante en el concepto de promoción, prevención, rehabilitación, inclusión y salud pública en general. Esta disciplina se ha expandido a diversas áreas de la atención a las personas y ha demostrado un impacto positivo en los sistemas de salud de diversas naciones. Este artículo tiene como objetivo describir la historia y evolución de la TO en Costa Rica, su impacto en la salud pública, así como los principales retos para la formación profesional que respondan a las necesidades sociales y sanitarias actuales, así como las emergentes de la población del país.
Optimasi Konsentrasi Ekstrak dan Bahan Pengikat Polivinil Pirolidon pada Granul Ekstrak Daun Sirih Merah (Piper crocatum Ruiz & Pav) sebagai Antihiperurisemia
Authors: Laksmitawati Dian Ratih , Nurhidayati Liliek , Arifin Mochamad Futuchul , Bahtiar Bagus 
Published: August 2019

Ethanolic extract of red betel leaves (Piper crocatum Ruiz & Pav) has antihyperuricemic activity. In order to be applicable to consume, this extract need to be formulated into pharmaceutical dosage form. Granules which is packed in a tea sac bag was considered to be more practical andappropriate for person suff ering hyperuricemic, because they have to drink more water. In the granulation process, the he binder plays an important role so that this study aims to fi nd the optimal red betel leaf granule formula with variation on the extract dose and the polyvinyl pyrolidone (PVP) binder and prove granule activity in vivo in mouse hyperuricemia model. The extract was prepared by macerationthe leaves in 96% ethanol and sprayed dried by hot air. The powder was then formulated to granules form in 22 factorial design. The factors were the extract dosages (38% dan 47.51%) dan the amount of PVP (Polyvinyl Pyrrolidone) as a binder (0.5% dan 2%). The physical and chemical properties of the granules were evaluated, interaction dosage, PVP concentration and each properties was analysed by making the contour plot and superimposed contour plot to get the optimum formula. The in vivo antihyperuricemic activity of the granules was determined in hyperuricemic mice. The result showed that the optimum formula was found in granules that contained 42.5% extract and 1% PVP. At the equivalent dosage of 455 mg extract/kg, this granules formula had antihyperuricemic activity decreasing 54.2 %plasma uric acid level significantly. Thus it can be concluded that the optimum granules of ethanol extract of red betelleaf with 42.5% extra ct content and 1% PVP proved to have antihiperurisemia activity in mice induced by chicken extractand potassium oxonate.
EFFECT OF DRYING TECHNIQUE ON PHYSICAL QUALITY AND ANTI-INFLAMMATORY ACTIVITY OF WILD BETEL LEAVES (Piper sarmentosum Roxb. ex Hunter) EXTRACT
Authors: Fahleni Fahleni , Noviani Yuslia , Ramadhani Syarifah 
Published: August 2019

Kaduk betel leaves (Piper sarmentosum Roxb. ex. Hunter) contain flavonoids and alkaloids that have anti-inflammatory activity. Processing thick extract into a dry extract is required to determine the appropriate dose and increase the homogeneity. The purpose of tahhis study was to determine the effect of drying method to physical properties of dried powder and its antiinflammatory activity. Thick extract was dried using maltodextrin and lactose as adsorbents with concentrations of extract-adsorbent ratio 1: 1, 1: 2 and 1: 3. Method of drying were freeze drying and adsorbent. The evaluation results based on organoleptic dried powder, water content and flow properties. The water content of dried powder which is dried by freeze drying is smaller than that of the adsorbent. Organoleptic and flow properties of freeze dried powder results were also better. The best dried powder in each method tested its anti-inflammatory activity using BSA. The test results showed that the anti-inflammatory activity of dried extract of freeze drying (extract-maltodextrin 1:3) have higher activity with IC50 551.79 ppm compared to dried extract with adsorbent (extract-maltodextrin 1:3) 598.30 ppm.
Pembuatan, Karakterisasi dan Uji In Vitro Nanopartikel Emas Berbasis Konjugat Gom Arab-Vinkristin
Authors: Pertiwi Ratih Dyah , Djajadisastra Joshita , MUTALIB ABDUL , Pujiyanto Anung 
Published: August 2019

Gold nanoparticles (AuNP) are potentially developed as nanomedicine because AuNP is easily synthesized, functionalized, and biocompatible. With gum arabic as a stabilizer, vincristine was conjugated with gold nanoparticles. As a reducing agent, it used 0.02 M Natrium Boro Hidrat (NaBH4) solution. Gold nanoparticles (AuNP) coated with conjugated gum Arabic (GA) and vincristine (VCR) were successfully synthesized and characterized. The conjugation of GA-VCR and AuNP displayed a narrow hydrodynamic particle size distribution with average size < 100 nm by TEM and PSA (particle size analyzer). We investigated the cytotoxic activity of conjugated vincristine-gum arabic-gold nanoparticle by tetrazolium salt assay (MTT) using cancer cell line CCR-CEM. Cytotoxic activity of conjugated VCR-GA-AuNP before and after purification by Size Exclusion Chromatography (SEC), against leukemia cell line CCRF-CEM, was described by IC50 value. All formulation had a cytotoxic of activity with IC50 <20 μg/ml. The IC50 of samples against CCRF cell line were 1,026 μg/mL and 2,607 ug/mL, respectively.
In Vitro Enzyme Tyrosinase Inhibitory Activity Test on Liquorice Root Extract Cream (Glycyrrhiza glabra L.)
Authors: Noor Siti Umroh , Faridah Faridah , Magdalena Pamela 
Published: August 2019

Liquorice root extract (Glycyrrhiza glabra L.) contains glabridin, an isoflavone substance that has the ability to inhibit the oxidation of L-tyrosin and L-DOPA in the formation of melanin, therefore it can be used as skin whitening. The aim of the study was to determine the potential of the best skin whitening cream using positive control of kojic acid. Formulated 1 blank formula, 3 cream formulas using various concentrations of ethanol extract 70% liquorice roots of (0.01, 0.11, 1.01)% based on the value of tyrosinase inhibition activity in vitro from extracts of (50, 75, 100)%. Spectrophotometric method is used to measure the absorption of dopacrome by a microplate reader which was incubated at 37°C at λ 490 nm for 20 minutes. Oil in water cream was prepared by mixing extract with cream base at a temperature of 70-75°C at a speed of 400 rpm for 25 minutes. Stability test was carried out for 4 weeks at room temperature storage and a temperature of 40°C, evaluated for physical quality. The results of determination of IC50 of kojic acid was 20.88 µg / mL; IC50 of extract variation were (126.75; 1130.90; and 10092.41) µg / mL respectively. Cream has milky white-yellowish color; smell of flowers; soft texture; homogeneous; there is no separation; has type M/A; plastic thixotropic flow properties; has an increasing value including viscosity, spreadability, globule size, and pH, which are respectively (455000-620000)cPs, (2695.82-3545.83)mm2, (54.66-66.27)μm , and (4.44-5.04); tyrosinase inhibition activity in formula 1, 2 and 3 were stored at weeks 0, 2nd and 4th were respectively (1.78; -25.74; 22.04)%, (6.74; 6, 12; 4.49)%, and (-28.78; 53.06; 20.32)%. It can be concluded that the cream formula containing liquorice root extract with a concentration of 1.01% is the best formula so it can be used as skin whitening.
Implementasi Kebijakan Publik dari Perspektif Penyelenggaraan Pengawasan
Authors: Agindawati Isye Nuriyah 
Published: August 2019

The study presented in this paper analyzes the implementation of public policy oversight. the purpose of supervision is considered effective when in accordance with the principles of supervision. The Research uses secondary data, with descriptive analysis methodology by analyzing data and formulating conclusions. The results of the study indicate that the future examiners should be able to take a more strategic role, to provide recommendations for solutions, for the implementation of better policies, as guardians of development. Abstrak Studi yang disajikan dalam makalah ini menganalisis penyelenggaraan pengawasan kebijakan publik. tujuan pengawasan dianggap efektif manakala sesuai dengan prinsip prinsip pengawasan. Penelitian menggunakan data sekunder, dengan metodologi analisis deskriptif dengan cara menganalisis data dan merumuskan simpulannya. Hasil penelitian menunjukkan bahwa pemeriksa ke depan seharusnya dapat mengambil peran lebih strategis, untuk memberikan solusi rekomendasi, bagi implementasi kebijakan yang lebih baik, sebagai pengawal pembangunan.
Authors: Andreotti Giuliana 
Published: August 2019

Brasília, capital federal do Brasil, é a terceira, após a colonial Salvador na Bahia e a imperial Rio de Janeiro. É um lugar lendário, dominado pelo charme do surreal que envolve e aprisiona. Uma cidade de paixões antes que uma cidade de poder. Nascida do nada em brevíssimo tempo (1956-1960), para além de qualquer propósito político-econômico e simbólico, foi planejada e construída com a intenção consciente de se fazer dela uma obra de arte. A capital é um modelo de planejamento urbano espetacular e monumental, em constante equilíbrio entre criação e abstração. Está localizada no interior do Brasil, no vasto deserto do Planalto central, que dilata o sentimento de espaço infinito, apresentado pelos grandes vazios, também presentes nas áreas urbanas. A ilimitada extensão do altiplano e o amplo dilatar-se da curva celeste exprimem uma ordem absoluta, eterna, revelando qualidades cósmicas. As mesmas qualidades são encontradas na composição geométrica do tecido urbano e, principalmente, na tendência abstrata da arquitetura que dissolve a materialidade das construções. Este trabalho tem como objetivo considerar as características mais relevantes da metrópole e ilustrar os longos preparativos para a sua fundação, que ocorreu respeitando o clássico projeto conceitual dos processos de territorialização.
An Analysis Of Derivational And Inflectional English Morphemes
Authors: Halawa Amosi 
Published: August 2019

derivation and inflection Morpheme is one of the elements present in the field of morphology. Where the morphology is the study of morphemes, and morphemes are elements of language that have the meaning of the free element and bound elements. The problems that exist in this research is to analyze the morpheme of derivation and inflection contained in Jakarta Post. By understanding the derivation and morpheme inflection it can easily develop vocabulary, from one word can gain many meanings
This research is a type of research belonging to linguistic field. The research also used qualitative descriptive research method. This research method is a method that refers to the form of words taken from the data source by explaining the intent of data intention. In addition, this research also uses research libraries (library research). This literature research only discusses existing data data by processing and developing data by using morphological theory that supports the research.
The first step used by the author is to collect data taken from the source, after that the data are all collected then the writers classify the data in several groups. Since in this study only discusses the three topics of the problem, the first is to classify all types of derivation and morpheme inflection found in the Jakarta Post newspaper, the second is the function of each morpheme, and the last is the rule that belongs to the derivation and morpheme inflection The.
Based on this study, the writers found the uniqueness caused by derivation and morpheme inflection when combined with other morphemes. If the morpheme derivation is compared with the free morpheme it will have a different meaning and sometimes even change the word class. While morpheme inflection when compared with free morpheme it will have a grammatical function.
An analysis of symbols in spanish civil war as seen in For whom the bell tolls by ernest hemingway
Authors: Telaumbanua Faehusi , Yusuf Feby Meuthia 
Published: August 2019

The problem in this thesis is the symbols contained in the civil war in Spain. This fight has taken many casualties, death is common, but the soldiers continue to struggle and sacrifice for the hope of victory. The three themes of the struggle about death, sacrifice, and hope are reflected in the symbols of the war.
In this writing, literature research is taken as a method of data collection. As for data analysis methods, the authors perform systematic procedures with the understanding of novels, symbols and symbol analysis, as well as semiotic theory. Data collection techniques use documentation techniques in finding data relevant to the subject. In data analysis techniques, the authors use structural techniques by analyzing novels based on the elements that shape them.
The results of the research in this thesis are: 1) dynamite is a symbol of death, it can be connected with dynamite properties that can destroy anything around him, here are three Robert who aims to destroy the enemy by installing dynamite, 2) dynamite trigger is a symbol of sacrifice from the The main character, without any trigger, dynamite will not be explosive, Robert in this novel self-criticism to prevent enemies from being able to chase his fleeing friends, 3) the bridge as a symbol of hope, this is connected with the nature of the bridge connecting the two Side, Robert at the end of the story gives hope to his friends to stay safe from the battlefield.
Analysis of The English Closed Compound Words
Authors: Yusuf Gina Lora 
Published: August 2019

Compound Words is a part of elements that finding in morphology. Morphology is learning about morpheme and morpheme is the element of language that have meaning and also support the meaning. The morphology will involve two element, they are free element and not free element. The problem in this research is analyzing compound words that find in Jakarta Post. Compound words that describe in this research is closed compound words.
This research is kind of linguistic. This research also use descriptive qualitative method. The method of this research is the method that describe the word, sentences and paragraph which take from the source data with describe the meaning of the data. Beside that, this research also use library research. The library research just talk about the data that already prepare by the analyze data that have been get from the source data by using basic theories that support this research. In this research, the researcher take the source data from one edition of Jakarta Post Newspaper. All of data that needed come from that source.
The first step that use by the researcher is collecting the basic data which take from the source data. After that the basic data will be collecting, so the researcher will be grouping the data based on the type. Based on the limitation problem of this research just analyze four problems, so analyzing the data just describe four problems. The first problem is the form of compound words are combining that find in Jakarta Post Newspaper. The second problem is what is the meaning of compound word before and after combination. The third is the syntactic function of compound words that has been combined. And the last is the rule that have in compound words.
Based on the research, the researcher find the unique of the word that appear from the compound words. among if one word combine with another word so the word have a different meaning. There are some meaning still follow the basic meaning and also there are some meaning make a new meaning and doesn’t describe the two words. the unique take from the form data, the function and also the rule that have in the words. Based on this research, the researcher understand about the compound words.
Rituximab-associated Vasculitis Flare: Incidence, Predictors, and Outcome
Authors: Desbois Anne Claire , Biard Lucie , Sène Damien , Brocheriou Isabelle , Rouvier Philippe , Lioger Bertrand , Musset Lucile , Candon Sophie , Zenone Thierry , Resche-Rigon Matthieu , Piette Jean-Charles , Benameur Neila , Cacoub Patrice , Saadoun David 
Published: August 2019

Objective.To report the incidence, predictors, and outcome of rituximab (RTX)-associated autoimmune disease flare.Methods.We conducted a retrospective study in a tertiary referral center from 2005 to 2015. Disease flare was defined as the onset of a new organ involvement or worsening of autoimmune disease within 4 weeks following RTX.Results.Among the 185 patients, we identified 7 disease flares (3.4%). All were due to type II mixed cryoglobulinemia vasculitis. Vasculitis flare occurred after a median time of 8 days (range 2–16) following RTX infusion and included acute kidney insufficiency (n = 7), purpura with cutaneous (n = 7), gastrointestinal (GI) tract involvement (n = 4), and myocarditis (n = 1). Patients with RTX-associated cryoglobulinemia vasculitis flare had these conditions more frequently: renal involvement (p = 0.0008), B cell lymphoproliferation (p = 0.015), higher level of cryoglobulin (2.1 vs 0.4 g/l, p = 0.0004), and lower level of C4 (0.02 vs 0.05, p = 0.023) compared to patients without flare after RTX (n = 43). Four patients (57%) died after a median time of 3.3 months. The 1-year survival rate was poorer in patients with vasculitis flare after RTX compared to their negative counterpart [43% (95% CI 18–100) vs 97% (95% CI 92–100), p < 0.001]. Immunofluorescence analysis of kidney biopsy in patients with worsening RTX-associated vasculitis highlighted the presence of RTX-, IgM-, and IgG1-positive staining of endomembranous deposits and thrombi within kidney lesions.Conclusion.RTX-associated cryoglobulinemia vasculitis flare is associated with high mortality rate. We provided evidence that kidney lesions are due to immune complex deposition and to glomerular obstruction by cryoglobulinemia and RTX.
Estágio supervisionado na Educação Física: a mobilização dos saberes docente
Authors: Carvalho Taynara Franco de , Souza Neto Samuel De 
Published: August 2019

Este trabalho focaliza a formação de professores de Educação Física no Estágio Supervisionado. Ele tem como objetivo central compreender os saberes que são mobilizados no Estágio Supervisionado. Opta-se pela pesquisa qualitativa, estudo descritivo, utilizando como técnicas: entrevista com 10 estagiários e sete professores e análise de conteúdo. Os participantes apontaram que a construção dos saberes e o resgate das experiências são continuas, tendo como influências a escolarização, a prática docente e a realização de cursos. A mobilização dos saberes (disciplinar, curricular, tradição pedagógica, ação pedagógica) pelos estudantes no estágio ocorreu de acordo com as necessidades e desafios desse processo, formando uma espécie de reservatório. Desse reservatório de saberes, os professores mobilizam o saber experiencial (uma amálgama de saberes) na supervisão e orientação do estágio. Nessa base de conhecimento, o professor se abastece, enquanto que o estudante se orienta na prática de ensino.
Respostas neuromusculares e fisiológicas durante o jogo em atletas de futsal feminino
Authors: Kassiano Witalo , Jesus Karla , Assumpção Cláudio , Lamboglia Carminda , Mendes Alisson , Barbosa Ralciney , Sabóia Wilson , Simim Mário , Medeiros Alexandre Igor Araripe 
Published: August 2019

O presente estudo testou se existem diferenças, nas respostas fisiológicas e neuromusculares em atletas de futsal durante um jogo amistoso. A amostra foi composta por seis atletas de futsal do sexo feminino (21,8 ± 3,9 anos; 57,4 ± 4,1 kg; 159,0 ± 2,7 cm de altura; 19,0 ± 3,3% gordura corporal e 7,8 ± 1,8 anos de tempo de prática). A frequência cardíaca (FC) foi monitorada durante toda a partida. O salto com contramovimento, resistência de força explosiva de membros inferiores e lactato sanguíneo foram avaliados antes, após o final do primeiro e segundo tempo de jogo. Para comparação das variáveis neuromusculares e fisiológicas entre os diferentes momentos, nós utilizamos as diferenças de médias estandardizadas (DME), intervalo de confiança (IC = 90%) e probabilidades de haver diferenças com relevância clínica. A FC máxima (FCmáx) foi de 186,6 ± 10,6 e 185,8 ± 8,3, primeiro e segundo tempo, respectivamente. Houve um aumento substancial do lactato do momento que antecedeu o início da partida para o final do primeiro (2,1 ± 0,3 para 6,3 ± 2,3 mmol/L-1, DME = 5,25 (3,28: 7,21), 100/0/0; most likely) e segundo tempo (2,1 ± 0,3 para 5,4 ± 1,3 mmol/L-1, DME = 4,62 (3,19: 6,04), 100/0/0; most likely) de partida. A performance de atletas femininas de futsal não foi suprimida após uma partida amistosa, sugerindo que, em dias de jogos consecutivos, o desempenho para o sistema neuromuscular possa ser restaurado logo após o término do jogo.
Improving Safety of Intravenous Prostacyclin Administration to Pediatric Patients With Pulmonary Hypertension
Authors: McSweeney Julia , Rosenholm Emily , Penny Katherine , Mullen Mary P. , Kulik Thomas J. 
Published: August 2019

Background
Pulmonary hypertension is a rare, life-threatening disease with limited therapeutic options and no definitive cure. Continuous intravenous prostacyclin therapy is indicated for treatment of severe disease. These medications have a narrow therapeutic index and a brief half-life; therefore, administration errors can be lethal.

Objective
To reduce medication errors through an inpatient program to improve, standardize, and disseminate continuous intravenous prostacyclin therapy practice guidelines.

Methods
Data were collected from the electronic safety reporting system of a single hospital to determine the number and types of continuous intravenous prostacyclin therapy errors that were reported over an 8-year period. A clinical database and hospital pharmacy records were used to determine the number of days on which hospitalized pediatric patients received the therapy.

Interventions
A nursing-directed quality improvement initiative to enhance the safety of continuous intravenous prostacyclin therapy for pediatric patients was begun in January 2009. Efforts to improve safety fell into 4 domains: policy, process, education, and hospital-wide safety initiatives.

Results
The number of therapy errors per 1000 patient days fell from 19.28 in 2009 to 5.95 in 2016. Chi-square analysis was used to compare the result for 2009 with that for each subsequent year, with P values of .66, .35, .16, .09, .03, .12, and .25 found for 2010 through 2016, respectively.

Conclusions
The trend in reduction of continuous intravenous prostacyclin therapy errors suggests that proactive processes to standardize its administration, emphasizing both policy and education, reduce medication errors and increase patient safety.