bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the Impact of VAK Learning Style on Teenager Level Language Learners in Indonesia
Authors: Bakri Rina Asrini , Rahman M. Asfah , Jabu Baso , Jassruddin Jassruddin 
Published: June 2019

This study aims at finding out whether Visual Auditory Kinesthetic (VAK) learning styles improve the It presents pre experimental design to see the impact of VAK learning style with one group pre-tested and post-tested, employing oral testing. The target group of this study was teenager level language learners at a school in Makassar Indonesia in the 2015/2016 academic year. Twenty nine students with average speaking ability participated in this study. A purposive sampling technique was used to recruit participants. The data was collected through an oral proficiency. The results of the data analysis indicated that there was a significant difference in the students’ English speaking skills before and after being trained using the VAK learning style. Results indicated that post-test was greater than pre-test in accuracy, fluency, comprehensibility. Based on the result of analysis can be concluded that the adoption of the VAK learning style can improve the English speaking skills and the methodology can be used as a preliminary strategy to assess students’ learning capability.
Percepción del acoso laboral entre estudiantes universitarios: medición en tres universidades de la ciudad de Pereira - Colombia
Authors: Dávila Londoño Carlos Andrés , Dávila Londoño Jorge Mario 
Published: June 2019

El objetivo fue analizar la prevalencia y las formas de acoso laboral, percibidas por estudiantes universitarios de la ciudad de Pereira, Colombia. La muestra estuvo compuesta por 228 participantes, de tres universidades de la ciudad. Se utilizó el cuestionario autoadministrado Barómetro Cisneros, desarrollado por el profesor Iñaki Piñuel de la Universidad Alcalá de Henares - España, que permite conocer el estado de la violencia en el entorno laboral de las organizaciones, a través de 43 ítems que objetivan y valoran 43 conductas de acoso psicológico de manera periódica. Los resultados muestran una prevalencia del acoso psicológico del 25% (52,6% mujeres y 47,4% hombres). Las conductas que representaron mayor frecuencia están relacionadas con las estrategias de acoso que buscan el desprestigio laboral (42,8%), intimidación manifiesta (15,9%), entorpecimiento del progreso (14,9%), y bloqueo de la comunicación (4,4%). El acoso vertical descendiente fue la principal forma de acoso relatada por los participantes. Los autores de las conductas de acoso fueron los jefes o supervisores (84,6% en promedio). Se encontró una asociación estadística significativa entre el género y las conductas de acoso laboral percibidas por los participantes, como también entre la tasa de acoso laboral y la capacitación sobre la prevención de este fenómeno.
COMPUTER-ASSISTED INTERVENTION (CAI) TO ENHANCE MATHEMATICAL LEARNING OF AUTISTIC STUDENTS: A CASE STUDY IN MELAKA
Authors: G. Pramudya , M. Sedek , F. Shahbodin , A.C. Amran , S.N.A. Ruslan 
Published: June 2019

Purpose of the study: To evaluate the efficacy of a CAI called MathTutor in helping autistic students to learn addition in mathematics.
Methodology: A pre-post-test experimental model was employed in the study. The study participants included three autistic male students who possessed all the prerequisite skills.
Main findings and novelty: The study participants were found to have been benefitted which indicates that MathTutor improves their learning abilities as an effective instructional strategy. The use of CAI enabled the participants to memorise their lessons and actively take part during the entire lesson.
Applications of this study: The study is beneficial for people involved in caring for autistic students with the help of computer assisted application. This will ease the burden of the carer takers of autistic children in dealing with their conditions while at the same enabling them to navigate the world.
INTEGRATED 21ST CENTURY SCIENCE, TECHNOLOGY, ENGINEERING, MATHEMATICS (STEM) EDUCATION THROUGH ROBOTICS PROJECT-BASED LEARNING
Authors: Hussin Hanipah , Yee Jiea Pang , Raja Rosly Raja Norhafiza , Omar Siti Rohana 
Published: June 2019

Purpose of the study: To propose a new framework on integrated 21st century STEM education through Robotics Project-based Learning, and secondly, to outline a Robotics Project-based Learning curriculum in the perspective of integrated 21st century STEM education.
Methodology: Content analysis was carried out to design a new framework. Secondary data collection technique was used.
Main Findings: The proposed framework can identify itself with each STEM curriculum in Science, Technology, Engineering and Mathematics. Educational robotics as a tool to integrate the fours discipline through project-based learning.
Applications of this study: The proposed framework is applicable in 21st century learning environment using student-centered approach. 21st century skills are enhanced through collaboration, creativity, critical thinking and communication while students carry out robotics project-based learning.
Novelty/Originality of this study: A new pedagogy of STEM integration in Malaysia education system. Hands-on and minds-on activities through robotics project-based learning promote higher order thinking in students.
MEASURING THE CORRUPTION MEASUREMENT MODEL (CMM) BASED ON MAQASID SHARIAH FRAMEWORK
Authors: Widiastuti Tika , Kirana Kusuma Chandra , Ratnasari Ririn Tri , Insani Taqiyah Dinda , Robani Anidah 
Published: June 2019

Purpose of the study: This paper will discuss the application of maqasid al shariah as a benchmark in the Corruption Measurement Model (CMM) based on Maqasid Syariah. Dimensions to be assessed on maqasid al shariah based on the opinions of Syathibi include hifdzun Dhin, hifdzun an-nafsh, hifdzun al-aql, hifdzun an-nasl, and hifdzun al-maal.
Methodology: In addition to successfully formulating all the relevant details of maqasid al shariah for corruption measurement, this study is the first research that uses quantitative methods like ANOVA on data from all provinces in Indonesia.
Main findings: The result is the average score from the Corruption Measurement Model (CMM) in Indonesia which is found to be good enough. The empirical study using ANOVA shows that there is no significant difference in the maqasid dimension among provinces in Indonesia, with a significance of 0.05.
Applications of this study: The results of this study enables researcher, practitioner and policy maker to understand the implication of corruption and its impact on the society.
Novelty/ Originality of this study: The application of maqasid al shariah is tested to explain the impact of corruption on the inadequacy of infrastructure and inefficient bureaucracy.
Pengaruh Ekstrak Buah Pare (Momordica charantia) Terhadap Titer Antibodi Ayam Broiler yang Divaksin Newcastle Disease
Authors: Komariyah Siti , Rahmahani Jola , Agustono Bodhi 
Published: June 2019

Tujuan dari penelitian ini untuk mengetahui pengaruh pemberian ekstrak buah pare (Momordica charantia) terhadap titer antibodi ayam broiler yang di vaksin ND berdasarkan hasil titer antibodi dengan menggunakan uji Hemaglution Inhibition (HI). Metode dalam penelitian ini adalah menggunakan metode Rancangan Acak Lengkap (RAL), sehingga jumlah sampel untuk 5 perlakuan adalah 50 ekor ayam broiler. Data hasil pemeriksaan uji HI dianalisa secara statistik menggunakan ANOVA dengan menggunakan software SPSS v22. Jika terdapat perbedaan pada masing-masing kelompok perlakuan maka dilanjutkan dengan Uji Duncan untuk melihat ada tidaknya perbedaan yang nyata antara kelompok perlakuan dengan kelompok kontrol.Titer protektif terhadap ND untuk ayam adalah 26 berarti jika di bawah nilai tersebut, maka antibodi di dalam tubuh ayam tidak dapat melindungi ayam dari virus, begitu juga sebaliknya, jika ≥26 maka antibodi di dalam tubuh ayam dapat melindungi tubuh ayam dari infeksi virus. Hasil Penelitian ini kelompok P0 berbeda nyata (p<0,05) dengan kelompok P1, P2, P3, P4 hal tersebut karena pada kelompok P0 merupakan perlakuan tanpa vaksin dan ekstrak buah pare. Kelompok P1 tidak berbeda nyata (p>0,05) dengan kelompok P2, P3, P4. Kelompok P2 dan P3 tidak berbeda nyata (p>0,05) dengan kelompok P1 dan P4 dan memiliki rataan titer antibodi yang sama. Kelompok P4 tidak berbeda nyata dengan kelompok P1, P2, P3 namun memiliki titer yang lebih tinggi. Kesimpulan dari hasil penelitian adalah pemberian ekstrak buah pare tidak berpengaruh nyata terhadap titer antibodi ayam broiler yang di vaksin Newcastle disease.
Isolasi dan Identifikasi Cemaran Bakteri Escherichia Coli pada Telur Penyu Lekang (Lepidochelys olivacea) yang Gagal Menetas Menetas di Sarang Semi Alami Pantai Boom Banyuwangi
Authors: Haprabu Bhima Rochman Satya , Primarizky Hardany , Wibawati Prima Ayu , Haditanojo Wiyanto 
Published: June 2019

Tujuan dari penelitian ini adalah untuk mengidentifikasi bakteri Escherichia coli dalam telur yang gagal menetas dari penyu Lekang (Lepidoehelys olivacea) di sarang semi-alami, pantai Boom, Banyuwangi. Bakteri diisolasi dari 12 kuning telur penyu yang gagal menetas dan dari induk penyu yang berbeda. Pengambilan sampel dilakukan dengan teknik sampel random berstrata. Kontaminasi E. coli dideteksi dengan menggunakan uji pendugaan, uji konfirmasi, dan uji biokimia IMVIC, berdasarkan Standar Nasional Indonesia 01-2332.1-2015 tentang cara uji mikrobiologi-bagian 1: Penentuan coliform dan E. coli pada produk perikanan. Hasil penelitian ini menunjukkan bahwa sebanyak 3 sampel atau 25% dari total sampel terkontaminasi E. coli, yaitu sampel B1, B3, dan C3. Berdasarkan Most Probability Number (MPN) Jumlah E. coli pada masing masing sampel adalah sampel B1 sejumlah 3 MPN/g, B3 sejumlah 7,2 MPN/g dan C3 sejumlah 9,2 MPN/g. E. coli bukan bakteri utama yang menyebabkan kegagalan penetasan telur penyu di sarang semi-alami, pantai Boom, Banyuwangi. Namun pada pengujian sampel ditemukan bakteri golongan koliform fekal pada sebagian besar sampel yaitu 8 sampel atau 66,67%, koliform non fekal sebanyak 1 sampel atau 8,33% dan non koliform sebanyak 3 sampel atau 25% dari total 12 sampel. Sumber kontaminasi E. coli diduga berasal dari induk penyu, lingkungan sarang semi-alami, dan pekerja Banyuwangi Sea Turtle Foundation.
TESTING THE EFFECTIVENESS OF THE CARHART MODEL FOUR FACTORS ON EXCESS RETURNS IN INDONESIA
Authors: Candika Yossy Imam 
Published: June 2019

One crucial information for investor in making their investment decision is to estimate asset-pricing level. The basic principle would be high risk, high return. This research is using Carhart model (1997): market return, size, book to market, and momentum. The goal of this research is to test and analyze the influence of Carhart Four Factor Model toward Indonesian stock' excess return. Dependent variable used in this research is stock' excess return, while independent variable used are Carhart four factor model. Population used is all non-financial firms listed in Bursa Efek Indonesia from year 2010 to 2012. Total samples are 150 firms. To test the model in this research, we firstly create ten portfolio groups by combining size-book to market and size-momentum. We use multiple regression analysis by using 10 regression analysis model based on previously built 10 portfolio combinations. Statistical test on variable excess market return toward stock return on 10 portfolio shows that there exist positive significant relationship to all models. SMB is significantly impacting portfolio return to 5 models. HML is significantly impacting portfolio return to 6 models. UMD impacting positively significant toward portfolio return on 2 models. Keywords: stock excess return, Carhart four factor model, market return, size, book to market, momentum.
Complement and T Cell Metabolism: Food for Thought
Authors: West Erin E. , Kemper Claudia 
Published: June 2019

AbstractThe classical complement system is engrained in the mind of scientists and clinicians as a blood-operative key arm of innate immunity, critically required for the protection against invading pathogens. Recent work, however, has defined a novel and unexpected role for an intracellular complement system—the complosome—in the regulation of key metabolic events that underlie peripheral human T cell survival as well as the induction and cessation of their effector functions. This review summarizes the current knowledge about the emerging vital role of the complosome in T cell metabolism and discusses how viewing the evolution of the complement system from an “unconventional” vantage point could logically account for the development of its metabolic activities.
PENGARUH POSISI DAUN PADA TANAMAN SIRSAK (Annona muricata Linn.) DAN AKTIVITAS ANTIBAKTERI SECARA IN VITRO
Authors: Wirastuty Reski Yalatri , Lallo Subehan , Sartini Sartini 
Published: June 2019

Daun Sirsak merupakan salah satu tanaman yang memiliki aktivitas sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui pengaruh letak posisi daun dan aktivitas antibakteri. Masing-masing bagian daun sirsak dimaserasi menggunakan etanol 70% menggunakan perbandingan 1:7 kemudian dilanjutkan pengujian antibakteri, analisis kualitatif menggunakan UFLC. Aktivitas antibakteri menggunakan metode Disc Diffusion Kirby-Bauer menggunakan medium MHA dengan waktu inkubasi selama 24 jam pada suhu 37°C terhadap bakteri Staphylococcus aureus dan Pseudomonas aeroginosa. Hasil penelitian menunjukkan bahwa ekstrak pucuk sirsak yang paling baik aktivitas antibakteri terdapat pada bagian pucuk yang memiliki daya hambat terhadap Staphylococcus aureus sebesar 12,73 mm dan Pseudomonas aeruginosa sebesar 11,83 mm.
Balanced gene retention, transcription and methylation levels between subgenomes produced by soybean-specific paleo-tetraploidization
Authors: Wei Chendan , Qin Jun , Wang Zhenyi , Wang Li , Ge Weina , Lei Tianyu , Li Xinyu , Sun Pengchuan , Yuan Jiaqing , Meng Fanbo , Zhang Zhikang , Liu Chao , Guo He , Sun Sangrong , Jin Ling , Liu Ying , Hou Yue , Yu Jigao , Li Xiuqing , Wang Jinpeng , Zhang Mengchen , Wang Xiyin 
Published: June 2019

Abstract
BackgroundPolyploidization creates duplicated sets of genomes in a plant. Dominance by a subgenome is often observed in a polyploid species. Here, we studied the duplicated genomic regions in soybean, which was affected by a tetraploidization 13 million years ago.ResultsBy referring to eudicot relatives, we detailed that duplicated genes are retained in a balanced manner among homoeologs. Moreover, we found that duplicated genes in colinearity in extant genome are expressed at balance. Notably, the DNA methylation patterns of duplicated genes shared similar methylation levels among three different soybean lines (W931A, WR016, and ZAYOU1), suggesting that either the epigenetic information could be maintained transgenerationally for millions of years or homoeologs in this paleo-autopolyploid species have similar methylation patterns under similar environment.ConclusionsThese findings support the paleo-autotetraploidy of soybean. We proposed that, if taking maize as a model plant for studying paleo-allotetraploids, soybean is a model plant for studying paleo-autotetraploids.
Efficacy and Safety of Immunotherapy and Standard of Care in High-Grade Gliomas: A Systematic Review and Meta-analysis
Authors: Zhang Shengnan , Xu Libo , Chen Guanyu , Wang Qian , Hu Xindan , Wen Naiyan , Liu Xiaomin , Peng Xinyu , Fan Lei , Guo Baofeng , Zhang Ling 
Published: June 2019

Abstract
BACKGROUND: While immunotherapy combined with standard of care (SOC) is often used for high-grade glioma (HGG), there have been few comparisons between immunotherapy combined SOC treatment (IMCT) and SOC alone. For clinicians seeking to increase immunotherapies’ efficacy, it is important to understand what interventions exist and their relative effectiveness.
METHODS: The Cochrane Library, Embase, Medline, and the Web of Science Core Collection were systematically searched by two librarians. Retrieved hits were screened for inclusion. Subgroup analysis and Cox proportional hazards modeling was used to examine factors associated with overall survival (OS). Progression-free survival (PFS), objective response rate (ORR), and occurrence rate of adverse events (AE) were included as secondary endpoints to further assess the efficacy and safety of IMCT. GRADE profiler was applied to assess the quality of evidence. This study is registered with PROSPERO, number CRD42019112356
RESULTS: The search yielded 2315 results of which 13 met eligibility criteria. We identified 13 publications, 14 randomized controlled trials (RCTs), and 5 historical-matched controlled trials(HMCTs). In a fixed effects model, Compared to SOC alone, IMCT improved OS (HR = 0.82; 95% CI 0.74-0.90; p < 0.0001), PFS (HR = 0.61; 95% CI 0.40-0.92; p = 0.019), ORR (RR = 2.13; 95% CI 2.56-2.92; p < 0.0001) bur increased the occurrence rate of AE (p < 0.0001).
CONCLUSIONS: It suggests that IMCT compared to SOC alone have considerable effectiveness. Our findings support the use of immunotherapy in brain tumor to improve HGG outcomes.
Ethical issues encountered by medical school students during the physical examination of female genitalia
Authors: Özcan Müesser , Yeniceri Emine Neşe , Küçük Mert 
Published: June 2019

Abstract
Background

The aim of the study was to identify the ethical issues encountered during the physical examination of the female genitalia, which can be deemed culturally intimate, by medical school students who have practiced genital examination so far on a limited number of models and find out the reasons of such issues.

Methods

The study was conducted with 120 voluntary medical school students in clinical years who completely filled out and delivered the forms.

Results

Students stated that while performing genital examinations on real patients during their clinical years, they faced various issues including the importance of taking patient's consent, disclosing their identity and proficiency, fearing to harm the patient due to lack of knowledge and skills, failing to perform genital examination, and having emotional problems. The rate of encountering such problems differed depending on students' gender and grade.

Conclusions

In clinical education, while they are equipped with self-confidence and proficiency, students should also be integrated in an environment where patient's comfort, ethical principles and values are preserved. This subject should be examined when ethical dilemmas constrain learning. In order to avoid ethical concerns during this process and ensure that the process can be managed positively by both parties, medical schools should put forth official policies and guidelines concerning the practice of genital examination in particular which is considered intimate by patients and share such policies and rules with both parties.
Evaluation of a new Rapid Antimicrobial Susceptibility system for Gram-negative and Gram-positive bloodstream infections: Speed and accuracy of Alfred 60 AST
Authors: Anton-Vazquez Vanesa , Samuel Adjepong , Cristina Suarez , Timothy Planche 
Published: June 2019

Abstract
Background

Blood stream infections (BSIs) are a major cause of morbidity and mortality. The time from taking blood cultures to obtain results of antibiotic sensitivity can be up to five days which impacts patient care. The Alfred 60 AST™ can reduce laboratory time from positive culture bottle to susceptibility results from 16-25 hours to 5-6 hours, transforming patient care.

Objective

To evaluate the diagnostic accuracy of a rapid antimicrobial susceptibility system, the Alfred 60 AST™, in clinical isolates from patients with BSIs and confirm time to results.

Methods

301 Gram-negative and 86 Gram-positive isolates were analysed directly from positive blood culture bottles following Gram staining. Antimicrobial susceptibility results and time-to-results obtained by rapid Alfred 60 AST system and BD Phoenix were compared .

Results

A total of 2,196 antimicrobial susceptibility test results (AST) were performed: 1,863 Gram-negative and 333 Gram-positive. AST categorical agreement (CA) for Alfred 60 AST™ was 95% (1772/1863) for Gram-negative and 89% (295/333) for Gram-positive isolates. Gram-negative CA: ampicillin 96% (290/301); ciprofloxacin 95% (283/297); ceftriaxone 96% (75/78); meropenem 97% (288/297); piperacillin-tazobactam 95% (280/295); gentamicin 94% (279/297) and amikacin 93% (277/298). The median time to susceptibility results from blood culture flagging positive was 6.3 h vs 20 h (p<0.01) for Alfred system vs BD Phoenix™.

Conclusion

Alfred 60 AST system greatly reduced time to antimicrobial susceptibility results in Gram-negative and Gram-positive BSIs with good performance and cost, particularly for Gram-negative bacteraemia.
Gamma Rays Mediated Mutagenesis of Super Koji (Aspergillus oryzae) to enhance the Thermostability and Production of CMCases: Process Scale-up at Pilot Level
Authors: Zeb Neelam , Rashid Muhammad Hamid , Aleem Bushra , Iftikhar Fariha , Saqib Anam , Ali Hazrat , Sher Hassan , Rehman Saif ur , Fatima Bilqees , Khan Waheed S 
Published: June 2019

Abstract
Background
The β-1, 4-endoglucanase belongs to cellulases group of enzymes, which hydrolyse β-1, 4 glucosidic bonds in the naturally occurring cellulose or synthetic Carboxymethyl cellulose CMC thus also named as CMCase. Endoglucanase from Aspergillus oryzae is favoured in food and feed industries due to its GRAS (generally regarded as safe) status and for relatively stable enzymes production.
Results
Current report is novel as it deals with the development of super Koji strain having hyper production of thermostable CMCases. Hence, the potent Koji’s mutant, hyper producer of thermostable endoglucanase was screened from the available mutants stock (Total = 52 variants), which was generated through gamma rays treatment of Super Koji strain (A. oryzae cmc1). Initially, seventeen (17) mutants hyper producer of CMCases were selected based on the basis of clearance zone index (CI) on the plates supplemented with 1% CMC. Afterwards, six mutants resistant to 2-deoxy-D-glucose were selected having enhanced CMCase production. Mutants’ next screening was on submerged CMCase production. Potent mutant 60(5) having 60 kRad γ-rays exposure showed 3.6 folds hyper CMCase production (6.02 U ml-1). The half-life of endoglucanse produce of A. oryzae mutant 60(5) was 29.42 min and 14.8 min at 55 ⁰C and 60 ⁰C, respectively, which was 4 folds higher than the control at 60 ⁰C. The LC-MS analysis showed that A. oryzae mutant 60(5) does not produce aflatoxins. Field Emission Scanning Electron Microscopy (FESM) of mutated Koji depicted that gamma radiations enhanced the stiffness of fungal mycelia. Kinetics of CMCase production by mutant 60(5) in 10 L and 200L fermenter was as: CMCase = 913 U dl-1 & 821 U dl-1; Specific growth (µ) = 0.064 & 0.082 hours; Cell mass doubling time (td) = 10.71 & 8.42 hours; Yield coefficient with respect to cell mass (Yp/x) = 59 Ug-1 & 89 U g-1 and Specific rate of CMCase production (qp) = 3.84 Ug-1h-1 & 7.37 Ug-1h-1 respectively.
Conclusion
We concluded, γ-rays induced potent mutations in mutant 60(5) resulting in hyper production of thermostable endoglucanase, which can withstand harsh industrial conditions. Hence, has great potential for applications in food & feed and other industrial processes.