bluuebunny/crossref_metadata_2025_split huggingface dataset:
La construcción de la periferia urbana en el Eje Atlántico Gallego a través de los hábitats de carretera. Lógica inmobiliaria, planificación y naturaleza adaptativa de lo urbano.
Authors: González López Javier 
Published: November 2018

ResumenLa metrópolis contemporánea es resultado de la interacción entre una dinámica global de difusión urbana y un soporte territorial local y específico. En el caso de Galicia la extensión de la ciudad sobre el territorio se ha producido mediante formas precarias de colonización de los ejes viarios y de la matriz rural por parte de la edificación. Esto ha sucedido porque, frente a la fortaleza de un proceso urbanizador que avanza siguiendo una lógica de minimización de cargas a los procesos inmobiliarios, se ha situado una administración pública débil, apoyada en una legislación del suelo que, aplicada a las condiciones del territorio gallego, permitía interpretar como urbanas situaciones rurales. Palabras clave Ciudad difusa, Urbanización, Matriz rural, Planeamiento, Forma urbana. AbstractThe contemporary metropolis results from the interaction between the global dynamics of urban sprawl and a territorial support that is local and specific. In Galicia, city growth over the territory has occurred through precarious forms of colonization by building iniciatives of both thoroughfares and the rural matrix. This happened because the strenght of urbanizing dynamics that procedeed by minimizing the burdens over real state was confronted by a weak public administration, supported by a land regulation that, applied to the Galician territory, allowed the treatment of rural situations as urban. KeywordsUrban sprawl, Urbanization, Rural Matrix, Urban planning, Urban form
El uso y los usuarios de tres bulevares de Madrid. Apropiación vs. ausencia
Authors: Rueda Chiriboga Maria Mercedes 
Published: November 2018

ResumenGenerar un sentimiento de apropiación por parte del usuario debería ser un objetivo primordial de cualquier intervención urbana, una característica que deberían tener los espacios públicos para que su funcionamiento fuese completo. Sin embargo, ¿qué pasa con los espacios que ya existen?, ¿generan este sentimiento en sus usuarios?, ¿cuáles son las características que deben tener estos espacios para que este sentimiento se genere? Estos son los cuestionamientos y puntos de partida para la realización de este Trabajo de Fin de Máster. Motivo por el cual se eligen 3 espacios públicos, bulevares, de la ciudad de Madrid, para desarrollar un ejercicio práctico, cualitativo y cuantitativo en el que se plantea encuestar a los usuarios de estos espacios e intentar identificar, de acuerdo a sus usos, perfiles, beneficios e importancia, el grado de apropiación que sienten los usuarios con respecto a estos espacios. Con este análisis se busca conseguir una aproximación al sentimiento que genera un determinado espacio a sus usuarios más frecuentes. Identificar sus percepciones, las rutinas que realizan y definir hasta qué punto se sienten parte de estos espacios.Palabras clave Espacio público, bulevar, apropiación, simbolismo urbano, usuario, encuesta. AbstractTo generate a sense of ownership by the user should be a prime consideration for any urban intervention, a feature that public spaces should have. However, what happens with the spaces that already exist?, what kind of feelings do they generate in their users?, what are the features that these spaces should have to generate this feeling? These are the questions and points of departure for the implementation of this Final Master Thesis. The reason why three public spaces boulevards are chosen within city of Madrid, to develop a practical, qualitative and quantitative exercise in which users are surveyed to identify, according to their uses, profiles, benefits and importance, the degree of ownership felt by users towards these spaces. This paper seeks to be an approximation to the feeling that a given space generates to its most frequent users. Identifying their perceptions, the routines they perform and defining their level of feeling of belongingness.KeywordsPublic space, boulevard, belongingness, urban symbolism, user, survey.
Acute cerebral infarction in a patient with an epidural catheter after left upper lobe resection: A case report
Authors: Kitajima Asuka , Otsuka Yuji , Sanui MD Masamitsu , Lefor MD/MPH Alan Kawarai 
Published: November 2018

Abstract
Background
There are several recent reports that left upper lobe lung resection is a risk factor for the development of postoperative thromboembolism. Although administering epidural analgesia is common in thoracic surgery, anesthesiologists should be alert when administering epidural analgesia to a patient undergoing left upper lobe resection, considering the increased risk of postoperative thromboembolism and the potential need for anticoagulation or fibrinolytic therapy in the immediate postoperative period.
Case presentation
A seventy-one-year-old female with a metastatic lung lesion developed a cerebral infarction approximately 30 hours after video-assisted thoracoscopic left upper lobectomy. Cerebral intravascular therapy was indicated and the epidural catheter was removed immediately to avoid formation of an epidural hematoma. Approximately four hours after onset, reperfusion was successfully established by aspiration of endovascular thrombi. She recovered with mild residual paralysis of the left upper extremity and was transferred to a rehabilitation facility.
Conclusions
We present a patient with a cerebral infarction after left upper lobe resection. Left upper lobe resection is associated with an increased risk of postoperative thromboembolism. Although the exact mechanism of thrombosis after left upper lobe resection is unclear, a judicious decision should be made regarding epidural catheter placement for postoperative analgesia.
Efficacy of rituximab in neuromyelitis optica: A meta-analysis
Authors: Gao Fulin , Chai Bingyan , Gu Cheng , Wu Ruipeng , Dong Tong , Yao Yuping , Zhang Yi 
Published: November 2018

Abstract
Background: Neuromyelitis optica (NMO) is a severe autoimmune disorder of inflammatory central nervous system, which often resulting in paralysis or blindness. Rituximab (RTX) is a mouse-human chimeric monoclonal antibody specific for the CD20 antigen on B lymphocytes used to treat many autoimmune diseases. This review performed a meta-analysis of the efficacy of rituximab use in NMO.
Methods: We searched through the databases of PubMed, Embase, and Cochrane Library. We compiled 28 studies in this meta-analysis: 19 used annualized relapse rate (ARR) ratio, 24 used Expanded Disability Status Scale (EDSS) score. Differences in the ARR ratio and EDSS score before and after rituximab therapy were the main efficacy measures. After a consistency test, the publication bias was evaluated and a sensitivity analysis was performed with mean difference (MD) of the efficacy of rituximab.
Results: A meta-analysis of 28 studies with 613 participants total was conducted. NMO patients have antibodies against aquaporin 4 autoantibody (AQP4-Ab) were recorded in 440 of 613 (71.78%). The mean difference of ARR ratio after rituximab therapy was 1.59 (95% CI, 1.33 to 1.85), and a mean difference 1.14 (95%CI, 0.95 to 1.33) reduction in the mean EDSS score. 345 of 563 patients (61.28%) reached a relapse-free state. 94 of 613 (15.33%) patients had adverse reactions.
Conclusions: RTX has acceptable tolerance, reduces the frequency of relapse, and improves disability in most patients. However, the potential impact of early diagnosis of NMO and treatment with RTX in reducing health-care costs and improving functional outcome should be carefully addressed in future studies.
Seattle-PAP trial: A Study to Evaluate the Efficacy of Seattle-PAP for the Respiratory Support of Premature Neonates
Authors: Backes Carl H. , Notestine RNC-NIC BSN Jennifer L. , Lamp RN-BC MS Jane M. , Balough IBCLC FACCE RN MSN Jeanne C. , Notestine Allison M. , Alfred RRT MS Crystal M. , Kern Juli M. , Stenger Michael R. , Rivera MS Brian K. , Moallem Mohannad , Miller Randy R. , Naik Apurwa , Cooper Jennifer N. , Howard MBA Christopher R. , Welty Stephen E. , Hillman Noah H. , Zupancic John A. F. , Stanberry Larissa I. , Hansen Thomas N. , Smith Charles V. 
Published: November 2018

Abstract
Background: At birth, the majority of neonates born at <30 weeks of gestation require respiratory support to facilitate transition and ensure adequate gas exchange. Although the optimal approach to the initial respiratory management is uncertain, the American Academy of Pediatrics endorses noninvasive respiratory support with nasal continuous positive airway pressure (nCPAP) for premature neonates with respiratory insufficiency. Despite evidence for its use, nCPAP failure, requiring intubation and mechanical ventilation is common. Recently, investigators have described a novel method to deliver bubble nCPAP, termed Seattle-PAP. While preclinical and pilot studies are encouraging with regard to the potential value of Seattle-PAP, a large trial is needed to compare Seattle-PAP directly with the current standard of care for bubble nCPAP (Fisher Paykel-CPAP; FP-CPAP).
Methods: We designed a multicenter, non-blinded, randomized controlled trial that will enroll 230 premature infants (220/7 to 296/7 weeks of gestation). Infants will be randomized to receive Seattle-PAP or FP-CPAP. The primary outcome is respiratory failure requiring intubation and mechanical ventilation. Secondary outcomes include measures of short and long-term respiratory morbidity and cost effectiveness.
Discussion: This trial will assess whether Seattle-PAP is more efficacious and cost effective than FP-CPAP in real-world practice among premature neonates.
Alterações no perfil da microbiota bucal durante permanência na UTI: colonização por patógenos respiratórios potenciais
Authors: Tulio Karoline de Souza Chinasso , Stramandinoli-Zanicotti Roberta Targa , Dirschnabel Acir Jose , Schussel Juliana Lucena , Wasilewski José Henrique Schettini , Krelling Andrea , Beltrame Olair  Carlos , Martins Carla Regina Worliczeck , Sassi Laurindo Moacir 
Published: November 2018

Introdução: Pacientes hospitalizados em Unidade de Terapia Intensiva (UTI) geralmente mostram má higiene bucal, o que contribui significativamente para o agravamento da contaminação local, com a presença de patógenos respiratórios potenciais. Objetivo: Caracterizar qualitativamente o perfil da microbiota bucal durante permanência na UTI, além da identificação de alterações bucais e salivares. Materiais e métodos: Foi realizado um estudo prospectivo em pacientes internados na UTI de um hospital oncológico, os quais foram avaliados clínica e microbiologicamente após 24 (T1), 72 (T2) e 120 (T3) horas consecutivas à admissão na UTI. Foram identificados os principais patógenos em cada momento e o perfil da microbiota oral foi comparado. Resultados: A amostra final foi de 30 pacientes, 23 homens e 7 mulheres, com idade média de 61 anos. Em T1, 96,67% dos pacientes apresentaram crescimento de microorganismos patogênicos, sendo identificados 14 tipos diferentes. Em T2 18 tipos de patógenos diferentes e em T3, 21 tipos, dos quais os mais prevalentes nas três coletas foram Staphylococcus não produtor de coagulase e Candida albicans. Clinicamente foram observados presença e progressão do biofilme visível (61%), cálculo (36,89%), condição periodontal deficiente (33,11%). Em relação à condição salivar verificou-se saburra lingual (92,11%), ressecamento labial (86,67%), hipossalivação (36,67%), assialia (52%) e escoamento salivar (8,89%). Conclusão: O biofilme do dorso de língua de pacientes em UTI pode representar um nicho considerável de patógenos respiratórios potenciais, uma vez que microorganismos etiológicos relacionados à pneumonia nosocomial foram isolados já no primeiro dia de internação, com a colonização subsequente por uma variedade de microorganismos predominantemente gram-negativos.Descritores: Pneumonia Aspirativa; Biofilmes; Infecção Hospitalar; Unidade de Terapia Intensiva.
Is self-perceived oral health status related to non-carious cervical lesions in Brazilian working adults?
Authors: Bomfim Rafael Aiello , Crosato Edgard 
Published: November 2018

This study evaluates the association of Non Carious Cervical Lesions (NCCLs), Oral Health-Related Quality of Life (OHRQoL) and Work Ability Index (WAI) in a Brazilian population of Workers. One hundred workers were evaluated in a CEREST (Worker´s Health Reference Center). Participants were examined for oral disease following WHO recommendations, and the Oral Health Impact Profile (OHIP) and Work Ability Index assessment was used to determine OHRQoL and capacity to work, respectively. Assessment of tobacco use and alcohol consumption was made by Fagestron tolerance and Audit test. Statistical analyses were performed using STATA version 13.0. Dimensions with highest OHIP scores were physical pain and psychological discomfort. In bivariate analyses, NCCLs was significant associated with OHIP-14 severity PR 3.8 (CI95%1.26-11.89) and with self-related of oral pain PR 2.16 (CI95% 1.06-4.40). In the multivariate logistic regression analyses, years of smoking habits OR 1.73 (CI95% 1.03-2.9) was significant associated with OHIP-14 severity, independent of other variables. OHIP14 was significant associated to WAI (p=0,02). Strategies for Monitoring oral health Brazilian workers and reduce tobacco use should be done by Brazilian Companies to support Work ability. For future investigations on OHRQoL, analyses of NCCLs should be included.Descriptors: Quality of Life; Oral Health; Occupational Dentistry; Occupational Health; Tooth Erosion.
Stiffness improvement methods and its application on design and optimization of large lens hood for space camera
Authors: Gong Xiaoxue , Zhang Lei , Wei Lei , Jia Xuezhi , Xuan Ming 
Published: November 2018

As an essential part of optical system, lens hoods consisting of shells and plates are designed mainly to protect optical system from unexpected light. Except for such basic function, the hood proposed in this paper has to load several subassemblies and will be applied in high-resolution and wild field-of-view space camera with strict mass limitation, which makes effective mechanical reinforcement and lightweight of hood quite necessary. To meet such requirements, stiffness improvement methods is promoted in this paper to help improve the constraint fundamental frequency and decide the areas where subassemblies can be placed. Subsequently, optimization on key sizes of the hood proceeds to achieve a higher fundamental frequency and a lower weight. Finally, a prototype is fabricated based on the optimal design and a sweep test is held to verify the analytical fundamental frequency. The prototype has large external dimensions (1960×1640×2055 mm) but weighs only 33.5 kg when loading several subassemblies which totally weight 15.95 kg. Sweep test indicates that experimental constraint fundamental frequency is 36.82 Hz. All the parameters coincide with that of theoretical design well. The whole work of this paper provides a worthwhile method to the design of lens hood with large external dimensions and high specific stiffness in space camera. Since the lens hood is a typical plate and shell structure, the method, design and optimization process in this paper may also be helpful to the plate and shell structure in which stiffness and lightweight are highly required.
Vibration characteristics analysis of mistuned bladed disk system based on mobile interface prestressed CMS super-element method
Authors: Zhang Liang , He Yuan , Yuan Huiqun , Li Xin 
Published: November 2018

A new mobile interface prestressed component mode synthesis (CMS) super-element method is proposed with the mobile interface prestressed and free interface super-element approach. Analysis accuracy of this method is verified by the cyclic symmetry analysis method and the direct method. The mistuning parameter of real blades is identified by modal testing and finite element method, and the vibration characteristics of the real mistuned bladed disk system are analyzed based on the mobile interface CMS method. The results showed that the maximum relative error of the dynamic frequency of tuned and mistuned examples are 0.0043 % and 0.1466 %, respectively, which can be to meet the requirement of analytical precision. Compared with the cyclic symmetry analysis method, direct method and fixed interface prestressed CMS super-element method, this method is more suitable for analyzing the vibration characteristics of arbitrary mistuned bladed disk system.
Flora fanerogâmica da região sudoeste do estado do Paraná, Brasil: uso e conservação
Authors: Bechara Fernando Campanhã , Topanotti Larissa Regina , Schwade Guilherme Moacir , Silva Valeria Mariano da , Estevan Daniela Aparecida 
Published: November 2018

O sudoeste paranaense ainda carece de estudos sobre sua composição florística. Visando contribuir com o conhecimento sobre a flora da região, foi realizada uma compilação de trabalhos científicos publicados referentes à vegetação nativa dessa parte do Brasil, integrando-os com dados de diferentes herbários, o que gerou uma lista de espécies que configura a flora fanerogâmica da região sudoeste do Paraná. Verificou-se, para cada uma das espécies, o uso potencial, considerado medicinal, comestível ou madeireiro. Consultaram-se quatro listas de espécies ameaçadas para verificar o estado de conservação das referidas espécies botânicas. A flora fanerogâmica incluiu 665 táxons de 117 famílias, e os municípios sudoestinos registraram em média 29,16 táxons, sendo os maiores registros em São Jorge d’Oeste (299), Dois Vizinhos (186), Quedas do Iguaçu (118) e Marmeleiro (101). Quantoao uso, encontraram-se informações para 45,26% das espécies (301); a utilização medicinal foi observada em 264 táxons, o uso da madeira em 96 e o uso comestível em 50. Foram verificadas 122 espécies ameaçadas, das quais 55 apresentam algum uso potencial. O esforço amostral na região ainda é inexpressivo diante de sua rica biodiversidade.
QUALIDADE PERCEBIDA NO USO DAS CORES EM UMA CLÍNICA DE PSICOLOGIA VOLTADA PARA ADULTOS
Authors: Mello Fernandes Manuela , Maria de Lima Araújo Kátia 
Published: November 2018

Este estudo buscou averiguar a qualidade percebida no uso das cores a fim de entender e aplicar suas propriedades no design de interiores de estabelecimentos assistenciais de saúde. Ele procurou na história o uso da cor como elemento terapêutico, exemplificando experimentos realizados por teóricos, designers e psicólogos nos dias atuais, verificando a qualidade cromática percebida, por meio do significado e das sensações que cada cor transmite aos usuários do ambiente em que a cor foi trabalhada. Com base na compreensão da influência desse elemento, este trabalho apresenta uma proposta de uso de cores no design de interiores de uma clínica de psicologia voltada para adultos.
Implantes dentários em pacientes usuários de bifosfonatos: o risco de osteonecrose e perda dos implantes é real? Relato de três casos clínicos Dental implants in patients under bisphosphonate therapy: is the risk of osteonecrosis of the jaw and implant loss real? Report of three clinical cases
Authors: Stramandinoli-Zanicotti Roberta Targa , Deliberador Tatiana Miranda , Candido Bruno , Hurczulack Marcio Vinícius , Schussel Juliana Lucena , Torres-Pereira Cassius , Sassi Laurindo Moacir 
Published: November 2018

Introdução: A osteonecrose induzida por medicamentos (ONIM) é uma grave complicação da terapia com drogas antirreabsortivas, como os bifosfonatos (BFs). Embora ocorra com mais frequência em pacientes oncológicos, os quais utilizam BFs endovenosos, pacientes usuários de BFs orais para tratamento de osteoporose também se encontram no grupo de risco, principalmente quando procedimentos odontológicos cirúrgicos como exodontias e implantes dentários são realizados. Objetivo: Relatar três casos de pacientes que fizeram usode BFs no passado ou ainda utilizavam a medicação durante cirurgia para instalação de implantes dentários, abordando os principais fatores de risco para o desenvolvimento da ONIM. Conclusão: O conhecimento prévio pelo implantodontista dos efeitos adversos da terapia com drogas antirreabsortivas em pacientes que necessitam de reabilitação dentária é de extrema importância no manejo desses pacientes, uma vez que elas podem prejudicar a longevidade das reabilitações com implantes e induzir à osteonecrose dos maxilares,comprometendo não somente a saúde bucal como também interferindo negativamente na qualidade de vida dos pacientes.Introduction: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious complication of therapies with anti-resorptive drugs, such as bisphosphonates (BFs). Although it occurs more often in oncology patients who use intravenous BFs, patients who use oral BFs for osteoporosis are also in the risk group, especially when surgical dental procedures such as dental extraction or dental implants are performed. Objective: To report three cases of patients who were submitted to BF therapy in the past or were still using the medication during dental implants surgery and developed BRONJ and lost the implants. Conclusion: It is extremely important that the dentists are aware of the adverse effects of BF therapy in patients that require dental rehabilitation for the management thereof, since they can reduce the longevity of dental implants and induce osteonecrosis of the jaw, compromising not only their oral health but also these patients’ quality of life.
Alpha1-Antitrypsin Deficiency: Transition of Care for the Child With AAT Deficiency into Adulthood
Authors: Lin Henry C. , Kasi Nagraj , Quiros J. Antonio 
Published: November 2018

Importance:
Alpha1-antitrypsin (AAT) deficiency is a common, but an underdiagnosed
genetic condition, affecting 1 in 1500 individuals. It can present insidiously with liver disease in
children. Although clinical practice guidelines exist for the management of AAT deficiency, especially
with regards to pulmonary involvement, there are no published recommendations that specifically
relate to the management of the liver disease and monitoring for lung disease associated
with this condition, particularly in children.

Objective:
To review the literature on the management of AAT deficiency-associated liver disease in adults and children.

Evidence Review:
A systematic search for articles indexed in PubMed and published was undertaken.
Some earlier selected landmark references were included in the review. Search terms included:
"alpha1-antitrypsin deficiency"; "liver disease"; "end-stage liver disease"; "liver transplantation"
and "preventative management". Recommendations for the management of children with suspected or confirmed AAT deficiency were made according to the Strength of Recommendation Taxonomy scale.

Findings:
Liver complications arising from AAT deficiency result from the accumulation of mutated
AAT protein within hepatocytes. Liver disease occurs in 10% of children, manifested by cholestasis,
pruritus, poor feeding, hepatomegaly, and splenomegaly, but the presentation is highly
variable. A diagnostic test for AAT deficiency is recommended for these children. Baseline liver
function tests should be obtained to assess for liver involvement; however, the only curative treatment
for AAT deficiency-associated liver disease is organ transplantation.

Conclusion and Relevance:
There should be a greater vigilance for AAT deficiency testing among
pediatricians. Diagnosis should prompt assessment of liver involvement. Children with AATdeficiency-
associated liver disease should be referred to a liver specialist and monitored throughout
their lifetimes for the symptoms of AAT-deficiency-related pulmonary involvement.