bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histopathologic and Molecular Insights Following the Management of Ameloblastomas via Targeted Therapies – Pathological and Clinical Perspectives
Authors: Hirschhorn Ariel , Grynberg Shirly , Campino Gadi Abebe , Dobriyan Alex , Patel Vinod , Greenberg Gahl , Yacobi Rinat , Barshack Iris , Yahalom Ran , Toren Amos , Vered Marilena 
Published: December 2024

Abstract
Purpose
Current standard of care for ameloblastoma (conventional/unicystic - mural type) usually mandates extensive bone resection that frequently necessitates immediate reconstruction with serious sequelae, especially among young patients. BRAF-mutated ameloblastomas can be targeted by BRAF inhibitors to markedly reduce their size, enabling conservative removal of residual tumor. We aimed to characterize the effect of post-treatment histomorphologic changes.

Methods
Study included 14 patients, 11 mandibular and three maxillary tumors. Cases with very minimal residual tumor were defined as near-complete response, while those with mostly vital residual tumor as partial response. The epithelium component was scored for architectural and cellular changes, stroma - for fibrosis, inflammation and new bone formation, on a 3-tired score system: 0–no, 1–focal and 3–frequent changes. The mean scores of each parameter, total epithelium and total stroma were calculated and related to duration of treatment. Differences in the mean scores were investigated for mandibular tumors with near-complete response (n = 3) and partial response (n = 8).

Results
There were no significant differences in mean epithelium or stroma scores between tumors with near-complete and those with partial response (2.22 ± 0.68 versus 2.08 ± 0.43, p = 0.55; 1.41 ± 1.04 versus 1.43 ± 0.44, p = 0.27), suggesting that ameloblastomas have potential to undergo complete response to targeted treatment. This is probably dependent upon tumor/patient/treatment-related factors. Response to treatment appears to be predictable with neoplastic epithelium being first, while the stromal response increases during treatment, the entire process expanding over weeks-to-months.

Conclusion
Albeit preliminary, these are the first comprehensive histomorphologic findings on BRAF-treated ameloblastomas. Analyzing the suggested parameters in tumors with partial response, should highlight which tumor component has responded/failed to respond. This could serve as a basis for decision-taking toward subsequent steps in adjuvant treatment (e.g., follow-up, conservative surgery, modifications/changes in treatment regimen, combinations of approaches), with a prime aim of jaw preservation and minimal risk of sequelae.
Deciphering the causal landscape: genetic insights into sporadic vestibular schwannoma risk factors through Mendelian Randomization
Authors: Liu Yuyang , Feng Hui , Ma Hengchao , Li Jing , Yu Yang , Zhao Hua , Wang Xiaoguang , Li Yun , Zhang Jun , Liu Qi 
Published: December 2024

Abstract
Background
Sporadic vestibular schwannoma, a benign tumor affecting the vestibulocochlear nerve, poses significant health challenges due to its impact on hearing, balance, and facial nerve function. Despite known associations with genetic mutations and environmental factors, the causality between potential risk factors and sporadic vestibular schwannoma remains underexplored.

Objective
This study aims to investigate the causal effects of various genetically predicted risk factors on sporadic vestibular schwannoma utilizing a Two-Sample Mendelian Randomization (MR) approach to enhance understanding of its etiology and inform prevention strategies.

Methods
Leveraging data from genome-wide association studies (GWAS), we analyzed 29 risk factors across five categories: related diseases, lifestyle habits, nutritional status, learning ability, and laboratory indicators. The MR analysis employed instrumental variables (IVs) derived from single nucleotide polymorphisms (SNPs) to assess causal relationships, overcoming traditional observational study limitations.

Results
Our findings highlight significant associations between sporadic vestibular schwannoma and factors such as ovarian cancer, uterine fibroids and lifestyle habits including dietary intake and alcohol consumption. Notably, higher educational attainment and specific laboratory indicators like high-density lipoprotein (HDL) cholesterol levels were linked to altered disease risk. These results suggest a multifaceted etiology involving hormonal, cardiovascular, gastrointestinal, immune, and metabolic pathways.

Conclusion
This comprehensive MR study provides novel insights into the diverse risk factors contributing to sporadic vestibular schwannoma, emphasizing the role of genetic predispositions, hormonal influences, and lifestyle choices in its development. The associations identified underscore the need for a multidisciplinary research approach and targeted public health strategies to mitigate sporadic vestibular schwannoma risk. Further research into the underlying mechanisms of these associations is crucial for developing effective interventions and improving patient outcomes.
Carbon Nanofiber/Polyaniline Composite Aerogel with Excellent Electromagnetic Interference Shielding, Low Thermal Conductivity, and Extremely Low Heat Release
Authors: Chen Mingyi , Zhu Jian , Zhang Kai , Zhou Hongkang , Gao Yufei , Fan Jie , Chen Rouxi , Wang Hsing-Lin 
Published: December 2024

AbstractThe rapid development of communication technology and high-frequency electronic devices has created a need for more advanced electromagnetic interference (EMI) shielding materials. In response to this demand, a study has been conducted to develop multifunctional carbon nanofibers (CNFs)/polyaniline (PANI) aerogels with excellent electromagnetic interference shielding, flame retardancy, and thermal insulation performance. The process involved freeze-drying of electrospun CNFs and PANI nanoparticles followed by in situ growth PANI to coat the CNFs, creating the core–shell structured CNFs/PANI composite fiber and its hybrid aerogels (CP-3@PANI). The interaction between PANI and aniline (ANI) provides attachment sites, allowing additional ANI adsorption into the aerogel for in situ polymerization. This results in PANI uniformly covering the surface of the CNFs, creating a core–shell composite fiber with a flexible CNF core and PANI shell. This process enhances the utilization rate of the ANI monomer and increases the PANI content loaded onto the aerogel. Additionally, effective connections are established between the CNFs, forming a stable, conductive three-dimensional network structure. The prepared CP-3@PANI aerogels exhibit excellent EMI shielding efficiency (SE) of 85.4 dB and specific EMI SE (SE d−1) of 791.2 dB cm3 g⁻1 in the X-band. Due to the synergistic flame-retardant effect of CNFs, PANI, and the dopant (phytic acid), the CP-3@PANI aerogels demonstrate outstanding flame-retardant and thermal insulation properties, with a peak heat release rate (PHRR) as low as 7.8 W g⁻1 and a total heat release of only 0.58 kJ g⁻1. This study provides an effective strategy for preparing multifunctional integrated EMI shielding materials.
Accounting for Transparency: a Framework and Three Applications in Tax, Managerial, and Financial Accounting
Authors: Bischof Jannis , Gassen Joachim , Rohlfing-Bastian Anna , Rostam-Afschar Davud , Sureth-Sloane Caren 
Published: December 2024

Abstract
This article presents how the Collaborative Research Center TRR 266 Accounting for Transparency understands and studies transparency in organizations and markets. Starting from our transparency definition, which is rooted in a sender/receiver framework, we discuss how accounting, taxation, and their regulation affect transparency and illustrate selected economic consequences of transparency. We use three analyses to exemplify our research approach. These analyses illustrate that (i) firms use tax literacy and tax advice as substitutes in their strategies to cope with signals sent by tax regulators about complex tax regulations, (ii) trade-offs between tighter management controls and employee motivation lead firms to design hybrid work environments that facilitate information exchange within the firm, and (iii) managers’ understanding of how financial statement users benefit from firm disclosures affects the managers’ assessments of disclosure regulation. Overall we argue that transparency is context-specific, hard to achieve, and often has ambiguous consequences. We conclude by highlighting selected transparency-related questions that interdisciplinary work with a particular emphasis on institutional details can meaningfully address.
C3H7NH3PbI3@PVDF porous piezo-active film: a wearable potential bio-sensor
Authors: Sengupta Payal , Sahoo Dipankar , Ikbal Ashik , Ray Ruma 
Published: December 2024

AbstractRecently, sustainable energy sources have become a top concern worldwide to meet the increasing power demand. Simultaneously, micro-sensors, particularly wearable biosensors, environmental monitoring, space monitoring, etc., are becoming integral to our daily lives. Therefore, harvesting low power on a large scale is crucial, given the substantial demand for low-powered sensors in various applications. Piezoelectric energy harvesting can meet the need for consistent, low-power energy by scavenging mechanical energy from the surroundings. The inclusion of sol-gel derived propylammonium lead iodide (C3H7NH3PbI3) in polyvinylidene difluoride (PVDF) significantly enhances the ferroelectric phase content (β phase, approximately 66.7%) of the film. This composite has been used to fabricate a piezoelectric energy harvester (PPEH) that generates ~ 45 V open circuit voltage (VOC) and 17.8 µA/cm² short circuit current (JSC) under free-hand hammering. This performance is substantially higher compared to a PPEH made of neat PVDF. The flexibility of the PPEH offers an added advantage, making it suitable for use as a wearable biosensor. Additionally, the photo-active piezo response of the photodetector made from this composite is remarkable, making it effective as a photodetector.
Thermal Characteristics of Fly Ash-Slag Based Geopolymer Concrete for Sustainable Road Construction in Tropical Region
Authors: Girish M. G. , Shetty Kiran K. , Nayak Gopinatha 
Published: December 2024

AbstractGeopolymer cement is an emerging eco-friendly alternative to traditional Portland cement that offers a lower carbon footprint and the opportunity to use of industrial by-products such as fly ash and slag in its production. Although acknowledged as a dependable structural material in various studies, the potential of Geopolymer Concrete for paving applications remains under-explored. This research aimed to address this gap by developing Paving Quality Geopolymer Concrete (PQGC) and examining its mechanical and thermal properties. For applications in tropical climates, where the pavement surface may be subjected to temperatures in the range 30–60 °C, studies on thermal conductivity (λ), coefficient of thermal expansion (α), and stresses caused by daily and seasonal temperature changes in PQGC slabs need to be essentially studied. The study revealed that thermal conductivity of PQGC ranged from λ = 0.82 W/(m°C) to 0.71 W/(m°C) within the temperature range of 30–60 °C. The coefficient of thermal expansion for PQGC was evaluated using a setup based on AASHTO T 336–15 recommendations, and it was found, α = 8 × 10–6/°C, to be lower than that of Pavement Quality Concrete (PQC). Furthermore, stresses resulting from temperature fluctuations in PQGC, when computed using closed form solution and EverFe 2.26, were observed to be lower than those in PQC. Finally, PQGC has the potential to contribute to a cooler environment by emitting less heat into its surroundings and promotes the utilisation of fly ash and slag, making it a promising material for paving applications.
Achieving sustainability development goals of quality education through “VIDGRATION” method
Authors: Harith Siti Hawa , Zabidi Norsharina , Zulkifly Syazwan Syah , Mohammad Nur’Jila 
Published: December 2024

AbstractFlexible teaching by applying the “VIDGRATION” method, a video-based teaching tool used explicitly for non-law students, is one of the efforts to support the Sustainable Development Goal (SDG) 4 of Quality Education. This study investigates the effectiveness of the “VIDGRATION” method in improving non-law students’ understanding of a law-related subject. Non-law students mostly face difficulty with law-related subjects due to their unfamiliarity with law terms and wording. Therefore, these students cannot understand the lesson and score poorly during examinations. The “VIDGRATION” method is being introduced to facilitate the non-law students’ learning process. This qualitative study was undertaken toward 99 non-law students who enrolled on the Human Resource Management subject. This intervention study was conducted in three stages: problem identification, intervention and evaluation. All data were triangulated from the instructor’s and students’ reflections, focus group interviews, and comparisons between the pre-and post-quiz results. The results show that the “VIDGRATION” method has successfully improved the non-law students’ understanding of law-related subjects. In addition, the non-law students also enhance their cognitive skill, time management skills, readiness to study and develop critical thinking skills when applying real working scenarios.
Are mental dysfunctions autonomous from brain dysfunctions? A perspective from the personal/subpersonal distinction
Authors: Jurjako Marko 
Published: December 2024

AbstractDespite many authors in psychiatry endorsing a naturalist view of the mind, many still consider that mental dysfunctions cannot be reduced to brain dysfunctions. This paper investigates the main reasons for this view. Some arguments rely on the analogy that the mind is like software while the brain is like hardware. The analogy suggests that just as software can malfunction independently of hardware malfunctions, similarly the mind can malfunction independently of any brain malfunction. This view has been critically examined in recent literature. However, other less discussed reasons suggest that mental dysfunctions cannot be reduced to brain dysfunctions because mental dysfunctions are appropriately ascribed at the level of intentional mental states, while brain dysfunctions are solely related to abnormalities in anatomy and physiological processes. This paper questions why such a view would be upheld. The discussion is framed within the interface problem in the philosophy of cognitive science, which concerns the relationship between personal and subpersonal levels of explanation. The paper examines the view that an autonomist perspective on the personal/subpersonal distinction could justify the separation of mental dysfunctions, described in intentional terms, from brain dysfunctions, described in anatomical or physiological terms. Ultimately, the paper argues that the autonomist view cannot be upheld in psychiatry and, consequently, does not provide a principled justification for rejecting the reduction of mental dysfunctions to brain dysfunctions.
Feasibility study of FFPP thermoplastic lining for concrete pipeline rehabilitation: a case study
Authors: Xi Dongmin , Yan Yonggui , Shi Kebing , Ni Houming , Azimi Mohammadamin 
Published: December 2024

AbstractThis study investigates the feasibility and efficacy of Flexible Fiber-reinforced Polypropylene (FFPP) thermoplastic lining technology for the rehabilitation of concrete pipelines, specifically focusing on BONNA pipes. A custom-built test bench, featuring a 2-m high platform and multiple 90° bends, was designed to simulate the impact of pipe gallery space, adaptability and material accessibility of bent pipes, and cooling issues of long-distance dragging of materials. The simulation process utilizes a modified polyvinyl chloride (PVC) liner with unique thermomechanical properties. The liner, folded into an "H" shape, is mechanically inserted into the host pipe using a 2-ton winch and pulley system. During insertion, continuous high-temperature steam injection softens the material, facilitating expansion and conformity to the pipe's internal surface. Subsequently, cold air application rigidifies the liner below 60 °C while maintaining pressure, ensuring structural integrity and adherence to the pipe wall. Results revealed that while the FFPP liner successfully navigated through confined spaces, including a 300 mm expansion joint, spatial constraints led to localized cracking defects during inflation. Traction feasibility tests using a 2-ton winch demonstrated high pulling resistance in sections with multiple bends. The liner exhibited excellent adhesion in straight pipe sections but showed significant wrinkling and poor adhesion in 90° bends. Notably, the liner demonstrated remarkable strength, withstanding internal pressures exceeding 3.3 MPa in a DN300 pipe with a 10 cm diameter intentional defect, far surpassing the on-site hydrostatic test pressure of 9 bar. This study addresses a significant gap in trenchless rehabilitation research by evaluating the FFPP thermoplastic lining technique in complex pipeline geometries, an area previously understudied. While the technique shows promise for structural reinforcement in straight pipe sections, our findings reveal that its application in complex pipeline geometries requires further refinement. The study contributes to the field of trenchless pipeline rehabilitation in several ways: (1) it provides empirical data on FFPP liner performance in multi-bend configurations and confined spaces, (2) it identifies specific challenges such as localized cracking and poor adhesion in bends, and (3) it demonstrates the liner's exceptional strength under high pressure conditions. These insights advance our understanding of FFPP technology's potential and limitations in concrete pipe repair, paving the way for future research and development in optimizing trenchless rehabilitation techniques for complex pipeline systems.
Gaussian fluctuations for the two-urn model
Authors: Kolesko Konrad , Sava-Huss Ecaterina 
Published: December 2024

Abstract
We introduce a modification of the generalized Pólya urn model containing two urns, and we study the number of balls

$B_j(n)$

of a given color

$j\in\{1,\ldots,J\}$

added to the urns after n draws, where

$J\in\mathbb{N}$

. We provide sufficient conditions under which the random variables

$(B_j(n))_{n\in\mathbb{N}}$

, properly normalized and centered, converge weakly to a limiting random variable. The result reveals a similar trichotomy as in the classical case with one urn, one of the main differences being that in the scaling we encounter 1-periodic continuous functions. Another difference in our results compared to the classical urn models is that the phase transition of the second-order behavior occurs at

$\sqrt{\rho}$

and not at

$\rho/2$

, where

$\rho$

is the dominant eigenvalue of the mean replacement matrix.
Gaussian approximation and moderate deviations of Poisson shot noises with application to compound generalized Hawkes processes
Authors: Khabou Mahmoud , Torrisi Giovanni Luca 
Published: December 2024

AbstractIn this article, we give explicit bounds on the Wasserstein and Kolmogorov distances between random variables lying in the first chaos of the Poisson space and the standard normal distribution, using the results of Last et al. (Prob. Theory Relat. Fields165, 2016). Relying on the theory developed by Saulis and Statulevicius in Limit Theorems for Large Deviations (Kluwer, 1991) and on a fine control of the cumulants of the first chaoses, we also derive moderate deviation principles, Bernstein-type concentration inequalities, and normal approximation bounds with Cramér correction terms for the same variables. The aforementioned results are then applied to Poisson shot noise processes and, in particular, to the generalized compound Hawkes point processes (a class of stochastic models, introduced in this paper, which generalizes classical Hawkes processes). This extends the recent results of Hillairet et al. (ALEA19, 2022) and Khabou et al. (J. Theoret. Prob.37, 2024) regarding the normal approximation and those of Zhu (Statist. Prob. Lett.83, 2013) for moderate deviations.
The World Health Organization Access, Watch, and Reserve classification of antibiotics: an awareness survey among pharmacy professionals in a sub-Saharan country, Zambia
Authors: Mudenda Steward , Wataya McDonald David , Mufwambi Webrod , Chizimu Joseph Yamweka 
Published: December 2024

Abstract

Background:
Antimicrobial stewardship programs are very essential in addressing the problem of drug-resistant infections. The WHO Access, Watch, and Reserve (AWaRe) classification of antibiotics is essential in monitoring the rational use of antibiotics. Therefore, this study evaluated the awareness of the WHO AWaRe classification of antibiotics among pharmacy professionals in Zambia.

Materials and methods:
This cross-sectional study was conducted among 239 pharmacy professionals practicing in both private and public facilities in Zambia. A questionnaire was used to collect data which was subsequently analyzed using IBM SPSS version 23.0.

Results:
Of the 239 participants, 63% were male and most were pharmacists employed in the public sector. This study found that 58% of the pharmacy professionals were aware of the AWaRe classification of antibiotics. Consequently, only 36% of the participants agreed that they implemented the AWaRe framework of antibiotics in their healthcare facilities. Most of the participants (74%) agreed that implementing the AWaRe tool can promote the rational use of antibiotics and 98% of the participants were willing to learn more about the AWaRe tool through training or meetings.

Conclusion:
This study found a low awareness of the WHO AWaRe classification of antibiotics among pharmacy professionals. Our study further revealed that very few pharmacy professionals agreed that they had implemented the WHO AWaRe tool in their healthcare facilities. Hence, there is a need to strengthen antimicrobial stewardship programs by implementing the AWaRe framework and other recommended guidelines for monitoring the rational use of antibiotics.
National partnerships address critical needs in infection prevention and control
Authors: Kaufman West Erica , Doll Michelle , Fitzpatrick Margaret A. , Lewis James , Nori Priya , Passaretti Catherine , Restrepo Dalilah , Stevens Michael P. , Thyagarajan Rama , Hong Catriona 
Published: December 2024

Abstract
The COVID-19 pandemic highlighted gaps in infection control knowledge and practice across health settings nationwide. The Centers for Disease Control and Prevention, with funding through the American Rescue Plan, developed Project Firstline. Project Firstline is a national collaborative aiming to reach all aspects of the health care frontline. The American Medical Association recruited eight physicians and one medical student to join their director of infectious diseases to develop educational programs targeting knowledge gaps. They have identified 5 critical areas requiring national attention.
The tacit dimension and behavioural public policy: insights from Hayek and Polanyi
Authors: Festré Agnès , Østbye Stein 
Published: December 2024

Abstract
In this paper, we revisit the Knowledge Problem addressed by Hayek eight decades ago and emphasised more recently by Rizzo and Whitman in their critique of the new paternalist approach of mainstream behavioural economics promoted by Sunstein and Thaler. We do this in light of the work of Michael Polanyi. Polanyi developed a theory of knowledge which has some commonalities with Hayek’s but also departs from it by emphasising the tacit, personal and perceptual dimensions of any process of knowing, thus radically renouncing any attempt of a knowledge typology separating different types of tacit knowledge (TK) and even denying that general knowledge could exist independently of TK.