bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electroacupuncture on GB acupoints improves osteoporosis via the estradiol–PI3K–Akt signaling pathway
Authors: Wang Xinyu , Zeng Xiyu , Long Yu , Du Yanfei , Li Chang , Jiang Hua , Li Guang 
Published: November 2024

Abstract
Recent studies have reported that electroacupuncture (EA) can treat osteoporosis, but most of which were based on the “kidney governing bones” theory. However, the ancient Chinese medical textbook Huangdi Neijing pointed out that “Gallbladder Meridian of Foot Shaoyang” correlates with bone diseases, including osteoporosis, although the therapeutic regimens were lost after the Tang Dynasty. Here, we explored whether EA at GB points improves osteoporosis and its underlying mechanism. We constructed ovariectomized mice and treated them with EA at GB30 (Huantiao), GB34 (Yanglingquan), and GB39 (Xuanzhong) acupoints. EA treatment significantly improved bone parameters in osteoporotic mice, as evidenced by micro-computed tomography and histological assessment. Additionally, EA treatment elevated the serum levels of estradiol and SOD that were downregulated in osteoporotic mice. Transcriptome and qPCR results verified that EA treatment upregulated the expression of genes associated with bone formation. Moreover, transcriptome analysis revealed differential enrichment of the PI3K–Akt pathway. Furthermore, Western blot analysis demonstrated that estradiol partially counteracted a reduction in p-AKT expression induced by hydrogen peroxide. These findings indicate that EA treatment increases serum estradiol levels in mice, thus inhibiting osteoporosis induced by oxidative stress. This effect is achieved by activating the PI3K–Akt signaling pathway.
Transcriptomic analysis of liver immune response in Chinese spiny frog (Quasipaa spinosa) infected with Proteus mirabilis
Authors: Liu Wei , Tao Yu-Hui , Chen Jie , Lu Cheng-Pu , Zhang Le , Lin Zhi-Hua 
Published: November 2024

Abstract
The expansion of Chinese spiny frog (Quasipaa spinosa) aquaculture has increased the prevalence and severity of diseases such as “skin rot” disease, which is triggered by harmful bacteria. Previous studies have mainly focused on pathogen identification and vaccine development. However, frog immune responses following pathogenic bacterial infection have hardly been investigated. We thus examined the immune response of Chinese spiny frog to skin rot disease caused by Proteus mirabilis. The liver transcriptomes of Chinese spiny frog infected with P. mirabilis were sequenced using the MGISEQ-2000 platform. We identified a total of 138,936 unigenes, of which 32.35% were known genes. After infection with P. mirabilis, 801 genes showed differential expression, with 507 upregulated and 294 downregulated genes. These differentially expressed genes were enriched in pathways related to cytokine–cytokine receptor interaction, TNF signaling, and toll-like receptor signaling, according to Kyoto Encyclopedia of Genes and Genomes analysis. Following P. mirabilis infection, immune genes, including H2-Aa, hamp1, LYZ, CXCL10, and IRAK3, were significantly upregulated, while NLRP3, ADAM19, TYK2, FETUB, and MSR1 were significantly downregulated. The results provide important information on how the immune system of Chinese spiny frog responds to P. mirabilis infection and help understand the development of skin rot in cultured frog species.
Periprosthetic joint infections – a scoping review
Authors: Youssef Yasmin , Hättich Annika , Klepka Kim Lydia 
Published: November 2024

Abstract
Periprosthetic joint infections (PJIs) are dramatic complications after primary total joint arthroplasty. Despite increasing research in this field, the diagnosis, classification, and management of PJI remain a challenge. This is mainly due to the heterogenous clinical presentation of PJI in clinical routine and patient-related factors as secondary diagnosis and periprosthetic tissue condition. The early detection of PJI is essential for adequate treatment. However, there is no definition for PJI with 100 % sensitivity or a negative predictive value. This can potentially lead to a delayed or missed diagnosis of PJI. Furthermore, the surgical and antibiotic treatment is among the most discussed topics in PJI literature. There is no international consensus on the treatment of different PJI entities. Concludingly many aspects of PJI diagnostics and treatment remain controversially discussed and current studies are only comparable to a limited extent due to study heterogeneity and limited comparability.
Toeplitz operators associated with the Whittaker Gabor transform and applications
Authors: Mejjaoli Hatem 
Published: November 2024

Abstract
The Whittaker Gabor transform (WGT) is a novel addition to the class of Gabor transforms, which has gained a respectable status in the realm of time-frequency signal analysis within a short span of time. Knowing the fact that the study of the time-frequency analysis is both theoretically interesting and practically useful, the aim of this article is to explore two more aspects of the time-frequency analysis associated with the WGT including the spectral analysis associated with the concentration operators and the scalogram.
The construction of anti-pandemic image: a semiotic study of the role metaphors play in pandemic discourse in China
Authors: Li Ke , Wang Yanyu , Li Shukang 
Published: November 2024

Abstract
The pandemic has attracted extensive media attention around the world. In reports on the pandemic, metaphors are widely used to frame pandemic events through cross-domain mappings. Based on critical metaphor analysis, this study examines the metaphors in pandemic reports published in China Daily, the largest government-owned English-language newspaper in China and explores the metaphorical construction of China’s anti-pandemic image. We find more than 13 metaphor varieties, among which, the metaphors of war, journey, and family and friend are dominant. Through these metaphors, China is largely constructed as a people-oriented, united, resilient, responsible, and friendly country as well as a victim of political stigmatization. We argue that the stance and ideology of China Daily and the international background of infodemic influence the representation of China’s anti-pandemic image.
Motivational dysregulation with melanocortin 4 receptor haploinsufficiency
Authors: Steiner Alex M. , Roscoe Robert F. , Booze Rosemarie M. , Mactutus Charles F. 
Published: November 2024

Abstract
Obesity, by any standard, is a global health crisis. Both genetic and dietary contributions to the development and maintenance of obesity were integral factors of our experimental design. As mutations of the melanocortin 4 receptors (MC4R) are the leading monogenetic cause of obesity, MC4R haploinsufficient rats were fed a range of dietary fat (0–12 %) in a longitudinal design. Physiological and motivational assessments were performed using a locomotor task, a 5-choice sucrose preference task, an operant task with fixed and progressive ratios, as well as a distraction operant task. Dendritic spine morphology of medium spiny neurons (MSNs) of the nucleus accumbens (NAc), cells with ample D1 and D2 receptors, was also assessed. The percentage of lipid deposits in the liver of each rat was also analyzed using the Area Fraction Fractionator probe for stereological measurements. MC4R haploinsufficiency resulted in a phenotypic resemblance for adult-onset obesity that was exacerbated by the consumption of a high-fat diet. Results from the operant tasks indicate that motivational deficits due to MC4R haploinsufficiency were apparent prior to the onset of obesity and exacerbated by dietary fat consumption after obesity was well established. Moreover, MSN morphology shifted to longer spines with smaller head diameters for the MC4R+/− animals under the high-fat diet, suggesting a potential mechanism for the dysregulation of motivation to work for food. Increasing our knowledge of the neural circuitry/mechanisms responsible for the rewarding properties of food has significant implications for understanding energy balance and the development of obesity.
Elevated cerebral oxygen extraction in patients with post-COVID conditions
Authors: Liu Peiying , Ernst Thomas , Liang Huajun , Jiang Dengrong , Cunningham Eric , Ryan Meghann , Lu Hanzhang , Kottilil Shyamasundaran , Chang Linda 
Published: November 2024

Abstract

Objectives
Dysfunction of cerebral microcirculation due to SARS-CoV-2 infection has been postulated to be a plausible mechanism for the neurological symptoms of post-COVID-19 conditions (neuro-PCC), affecting oxygen homeostasis in the brain. In this study, we aimed to investigate the balance between cerebral oxygen delivery and consumption, measured by oxygen extraction fraction (OEF), in patients with neuro-PCC.

Methods
25 participants with neuro-PCC (8 previously hospitalized and 17 not hospitalized) and 59 age-matched healthy controls were studied. Global OEF was quantified using TRUST MRI and compared across the three groups. Associations between OEF and neurobehavioral measures were also evaluated in participants with neuro-PCC.

Results
OEF was significantly different (one-way ANCOVA-p=0.046) among the three groups, after accounting for age and sex. On post-hoc analyses, previously hospitalized neuro-PCC participants had significantly higher OEF (42.40 ± 5.40 %) than both uninfected controls (37.70 ± 5.09 %, p=0.032) and neuro-PCC participants without hospitalization (37.02 ± 5.05 %, p=0.015). Within the participants with neuro-PCC, OEF was significantly associated with locomotor function assessed with the 4-m walk gait speed score (β=−0.03, r=0.34, p=0.003).

Conclusions
Participants with neuro-PCC had altered cerebral OEF, which is also associated with slower locomotion. OEF is a promising marker for studying neuro-PCC.
Mexican queer influencers: corporeal-emotional social reconfigurations
Authors: Amao Ceniceros Melina 
Published: November 2024

Abstract

Purpose
The proliferation of queer influencers is framed in various phenomena that connect celebrity culture, digital psychopolitics and historical LGBTIQ+ movements, resulting in what we can call a post-reality. This study analyzes the tensions of bodies/emotions that arise from the visibility of queer influencers in Mexico in terms of representation and subjectivation of the sex/gender system, comparing visual narratives and political positionings or the lack of these in a necropolitical context for the LGBTIQ+ community.

Design/methodology/approach
A descriptive approach was carried out to have a overview of the diversity of profiles, and subsequently the mediabiography methodology was applied to a case study, with the selection of texts and digital images on an analytical model of three axes: corporality, emotionality and visuality.

Findings
The presence of Mexican queer influencers reconfigures dominant gender narratives and opens possible scenarios to recognize non-hegemonic corporalities and corporal practices. The content they generate articulates counter-narratives, counter-visualities and counter-emotionalities, such as pride in the face of shame, and anger in the face of the neoliberal depoliticization of pride.

Practical implications
Queer Studies guide the enactment of public policies that recognize the rights of sex/gender diversity. Mediabiography opens creative avenues for the study of contemporary visual narratives on social media.

Social implications
Counter-narratives, counter-visualities and counter-emotionalities legitimize the dignified existence of corporalities systematically and historically marginalized by the dominant gender model, and de-hierarchize life.

Originality/value
This is the first study that uses mediabiography for the analysis of visual narratives on social media. It contributes to new discussions for Communication Studies, Queer Studies and the Sociology of Bodies and Emotions.
Diffusion in nanoporous materials with special consideration of the measurement of determining parameters (IUPAC Technical Report)
Authors: Kärger Jörg , Valiullin Rustem , Brandani Stefano , Caro Jürgen , Chmelik Christian , Chmelka Bradley F. , Coppens Marc-Olivier , Farooq Shamsuzzaman , Freude Dieter , Jobic Hervé , Kruteva Margarita , Mangano Enzo , Pini Ronny , Price William S. , Rajendran Arvind , Ravikovitch Peter I. , Sastre German , Snurr Randall Q. , Stepanov Alexander G. , Vasenkov Sergey , Wang Yu , Weckhuysen Bert M. 
Published: November 2024

Abstract
The random motion (the diffusion) of guest molecules in nanoporous host materials is key to their manifold technological applications and, simultaneously, a ubiquitous phenomenon in nature quite in general. Based on a specification of the different conditions under which molecular diffusion in nanoporous materials may occur and of the thus resulting relevant parameters, a survey of the various ways of the measurement of the determining parameters is given. Starting with a condensed introduction to the respective measuring principles, the survey notably includes a summary of the various parameters accessible by each individual technique, jointly with an overview of their strengths and weaknesses as well as of the respective ranges of observation. The presentation is complemented by basic relations of diffusion theory and molecular modeling in nanoporous materials, illustrating their significance for enhancing the informative value of each measuring technique and the added value attainable by their combination. By providing guidelines for the measurement and reporting of diffusion properties of chemical compounds in nanopores, the document aims to contribute to the clarification and standardization of the presentation, nomenclature, and methodology associated with the documentation of diffusion phenomena in nanoporous materials serving for catalytic, mass separation, and other relevant purposes.
Planetarische Müllabfuhr – Gamechanger der Klimapolitik?
Authors: Edenhofer Ottmar , Kalkuhl Matthias 
Published: November 2024

Zusammenfassung
Dieser Beitrag spiegelt die in englischer Sprache gehaltene Thünen-Vorlesung von Ottmar Edenhofer auf der Jahrestagung des Vereins für Socialpolitik am 16. September 2024 in Berlin unter dem Titel „The (Missing) Third Pillar“ wider. Der Klimaökonom zeigt auf der Basis der gemeinsamen Forschung mit Matthias Kalkuhl, dass die internationale Klimapolitik vor einem Paradigmenwechsel steht: Durch CO2-Entnahmen („carbon dioxide removal“, CDR) sollen zusätzliche natürliche und technische Kohlenstoffsenken bereitgestellt werden, weil andernfalls die ambitionierten Klimaziele des Pariser Klimaabkommens nicht zu erreichen sind. CDR hat darüber hinaus die Funktion, die globale Kooperation zu erleichtern. Die Autoren entwickeln einen Vorschlag, wie eine Europäische Kohlenstoffzentralbank – die European Carbon Central Bank (ECCB) – eine Schlüsselrolle für Europas Beitrag zu einer planetarischen Müllabfuhr einnehmen kann. Den ökonomischen Anreiz liefern Clean-Up-Zertifikate, die die CO2-Entnahmen im EU-Emissionshandel finanzieren sollen.
Experimenting the compressive performance of low-carbon alkali-activated materials using advanced modeling techniques
Authors: Yang Xue , Wu Tong , Amin Muhammad Nasir , AlAteah Ali H. , Qadir Muhammad Tahir , Khan Suleman Ayub , Javed Muhammad Faisal 
Published: November 2024

Abstract
Activated alkali materials (AAMs) are progressively utilized as an alternative to Portland cement concrete owing to their widespread application and reduced environmental impact. This research employed multi-expression programming (MEP) and gene expression programming (GEP) to create predictive models for the compressive strength (CS) of AAMs based on a dataset of 381 entries with eight distinct variables. To further assess the significance of the factors influencing the CS of AAMs, sensitivity analysis was employed. In comparison to GEP, MEP was better at predicting AAM’s CS. The R
2 score of the GEP model was 0.953, which is lower than the MEP model’s 0.970 level. This was further backed up by the results of the statistical study and Taylor’s diagram. The results of the sensitivity analysis showed that specific surface area, aggregate volumetric ratio, and silicate modulus were the three most important parameters influencing the models’ outcomes. In comparison to models built in Python, the produced models yield novel empirical equations for AAM strength characteristic prediction. Researchers and professionals in the field could use these equations to find the best proportions for mix designs, cutting down on the need for repeated laboratory tests.
Zwischen Vulnerabilität und Resilienz: Der »Verstockungsauftrag« in der Theologie des Jesajabuches
Authors: Klein Anja 
Published: November 2024

Zusammenfassung
Ausgehend von einer Analyse des sogenannten »Verstockungsauftrags« in Jes 6,9–10 untersucht der Beitrag Konzeptionen von Vulnerabilität im Buch. Während im Ersten Jesaja die Vorstellung der situativen Verwundung dominiert, gehen die Texte im Bereich des Zweiten Jesaja von einer ontologischen Verwundung aus. Die zwei Vorstellungen gehen auf unterschiedliche Krisenerfahrungen zurück, die die theologiegeschichtliche Überlieferung ausbilden und sich für die Rezipientenkreise als resilienzfördernd erwiesen haben.
Maintenance-(Art)Work und die Arbeit am eigenen Bild
Authors: Kuhn Eva 
Published: November 2024

Abstract
This paper confronts two traditions that seem to complement each other: the sociohistorical tradition of women as reproductive and care workers lacking public visibility, and the art-historical tradition of women as images, as silent and fixed show objects. This combination of women’s work made invisible and their objectifying hyperexposure, which in turn relies on the invisibilization of the media and ideological dispositive, is addressed in a 1975 film by Chantal Akerman, Jeanne Dielman, 23, quai du Commerce, 1080 Bruxelles, in a particularly eloquent way. The paper places this film, a time-based portrait of a woman and her work, at the center of the investigation and takes it as a model of showing how the systemic determination of maintenance work – to maintain the status quo – can be overcome by making this work visible. By demanding our physical presence and endurance in facing and caring about another, this film enables us to perceive the details that make the difference and shows how maintenance (art)work can bring about change. It pointedly emphasizes the notion of the contemporary and allows us to ask the question of what is contemporary art once again.
De-linking Women and Nature: Care Work as a Subject of Art at the 1978 Venice Biennale
Authors: Bremer Maria 
Published: November 2024

Abstract
This essay revisits the 1978 Venice Biennale, titled From Nature to Art, from Art to Nature, to discuss the “gender neutral” use of both notions within the exhibition’s official discourse at the time. Against the backdrop of the 1970s, amid the momentum of second-wave feminism, initiatives concomitant to the exhibition discerned and challenged the persisting, though implicit, gendered implications of both art and nature, complicating the Biennale’s main narrative. These initiatives included self-organized shows by feminist collectives, namely the Gruppo Femminista Immagine from Varese and Donne/Immagine/Creatività from Naples. Informed by a Marxist perspective, both exhibitions, I argue, engaged with reproductive labor in original ways to contest and dismantle traditional assumptions of an inherent connection between women and nature.
Blurred Lines: Negotiating the In/Visibility of Maintenance in Feminist Art
Authors: Fiocco Fabiola 
Published: November 2024

Abstract
Visibility has been a key battleground for social movements such as feminism since the 1970s. In a socioeconomic landscape where the value and purpose of visibility vary according to gender, class, and race, it becomes even more urgent to critically investigate the mechanisms that organise it. By drawing from feminist and postcolonial theories, the article examines the negotiation of visibility in the artworks of Daniela Ortiz, Mayo Pimentel, and Liryc Dela Cruz. Through their work, these artists provide valuable insights into the aesthetic and political implications of in/visibility, particularly in relation to maintenance work, identified as a domain where these contradictions are most pronounced.
Voces testimoniales y realidad experimental en Guadalupe años sin cuenta del grupo la Candelaria
Authors: Rojas Muñoz Carlos Augusto 
Published: November 2024

The present article has as its main objective to depict the importance of testimonial voices as experimental reality through the analysis of the play “Guadalupe años sin cuenta” by La Candelaria theater company, which is set in the violent times lived in the 1950’s in Colombia. The reflection and analysis begins with the bipartisan and the importance of the guerrilla leader, José Guadalupe Salcedo Unda, from the Arauca region, in order to re-signify our historical processes from the subject-viewer and his critical thinking that that re-situates our daily living theater for the light of the truth and experience of our events.
МЕХАНОХИМИЯ ГИДРОКСИАПАТИТА И ЕГО ЗАМЕЩЕННЫХ ФОРМ
Authors: Н.В. БУЛИНА , М.В. ЧАЙКИНА 
Published: November 2024

Данная обзорная работа посвящена достижениям в области механохимии гидроксиапатита. Рассматриваются особенности механохимического способа получения данного минерала, реакции, происходящие в реакционной камере, параметры, влияющие на эффективность процесса, перечисляются достоинства метода. Показано, что в высокоэнергетических планетарных мельницах, с большим числом оборотов барабана, можно осуществлять быстрый механохимический синтез не только стехиометрического гидроксиапатита, но и разнообразных вариантов замещений в его структуре в широком интервале концентраций.
The present review is concerned with advances in the area of hydroxyapatite mechanochemistry. The features of the mechanochemical method for obtaining this mineral, the reactions proceeding in the reaction chamber, the parameters affecting the process efficiency are considered, and the advantages of the method are listed. It has been shown that rapid mechanochemical synthesis of not only stoichiometric hydroxyapatite, but also various options of substitution in its structure within a wide range of concentrations can be carried out in a high-energy planetary mill at a high frequency of vial rotation.
Análisis comparativo de la normativa contra el acoso sexual vigente en universidades públicas de Centroamérica
Authors: García Zamora Éricka 
Published: November 2024

El objetivo de este artículo es comparar la normativa sobre acoso sexual de las principales universidades públicas de Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica y Panamá, con el fin de establecer su alcance en tres líneas centrales: a) existencia de una regulación específica sobre este tipo de violencia, b) conceptualización del acoso sexual y, c) valoración de los mecanismos establecidos en relación con el enfoque de derecho que predomina en lo que atañe a derechos de las víctimas, la prescripción de este delito y, por último, las condiciones para la elevación y ratificación de las denuncias presentadas. El abordaje metodológico es cualitativo y la investigación es documental con base en fuentes primarias relacionadas con las normas y protocolos promulgados en las instituciones de educación superior y con fuentes secundarias. La investigación se circunscribe al periodo 1996-2020. Se concluye que la normativa existente responde a un modelo garantista de los procedimientos disciplinarios, enfocado en lo procedimental con base en normas consideradas apolíticas, el cual no toma en cuenta la variable sexo ni la asimetría de poder recurrente en las relaciones entre las partes involucradas.