bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parental Perspectives on Blenderized Tube Feeds for Children Requiring Supplemental Nutrition
Authors: Trollip Antonia , Lindeback Rachel , Banerjee Katie 
Published: July 2019

AbstractBackgroundFamilies choose pureed blenderized tube feeds (BTFs) over commercial formulas for several reasons, including the ability to provide foods with natural composition, improvements in physiological outcomes, intimate experiences for parental nurturing, and the benefits that come with family inclusion and mealtime engagement. Although dietetic associations cannot, as yet, recommend BTFs, many families still choose to commence them. We aimed to better understand the demographics of these families, their sources of information and support, and the perceived benefits in a community setting to tailor the support we provide these families.MethodsDietitians at a pediatric hospital in Sydney identified 21 children receiving BTFs. Questionnaires that focused on child/parent demographics, parental knowledge, dietetic support, and symptoms before and after commencing BTFs were distributed. Food diaries were also sent.ResultsTwelve respondents returned completed surveys. Thematic analysis indicated improvements in general health, emotional and social well‐being, and gastrointestinal symptoms. Respondents reported challenges with food preparation, nutrition adequacy, food storage, and prevention of tube blockages. Respondents primarily sought information online from social media and support groups. Likert scale analysis demonstrated positive outcomes for children receiving BTFs. Improvements were noted in general health, growth, nausea/vomiting, reflux, constipation, diarrhea, and social inclusion. Tube blockage was reported, however, and only changed from “never” to “rarely a problem.” Food diaries were not detailed enough for analysis.ConclusionFamilies continue to choose BTFs and report a range of benefits, accessing much of their information online. Health professionals should recognize this and openly provide support, guidance, and monitoring as appropriate.
Suvorexant for insomnia in patients with psychiatric disorder: A 1‐week, open‐label study
Authors: Kishi Taro , Sakuma Kenji , Okuya Makoto , Ninomiya Kohei , Oya Kazuto , Kubo Momoko , Matsui Yuki , Nomura Ikuo , Okuyama Yuji , Matsunaga Shinji , Iwata Nakao 
Published: July 2019

AbstractAimThere have been no previous reports on the efficacy and safety of suvorexant for insomnia in people with psychiatric disorders.MethodsThis one‐week, prospective, single‐arm, clinical trial of fixed dose of suvorexant (20 mg if ages 18–64 or 15 mg if age ≥ 65 years) for insomnia included 57 patients with psychiatric disorders who had experienced any of the following insomnia symptoms for four or more nights during the week prior to the start of the study: total sleep time (TST) <6 hours, time to sleep onset (TSO) ≥30 minutes, or two or more episodes of wake after sleep onset.ResultsThe mean age of the patients was 49.4 ± 17.3 years; 54.4% were women, 49.1% had a major depressive disorder, and 77.2% completed the trial. Compared with the baseline scores (the mean scores for the two days before the start of the study), taking suvorexant was associated with significant improvements in TST, TSO, wake time after sleep onset, and the patients' sleep satisfaction level at week 1. Adverse events included at least one adverse event (43.9%), sleepiness (28.8%), fatigue (11.5%), nightmares (5.8%), headache (3.8%), dizziness (3.8%), and vomiting (1.9%).ConclusionSuvorexant was beneficial for the treatment of insomnia in people with psychiatric disorders. However, this study was of short duration and included only a relatively small number of patients. A larger, long‐term study is needed to investigate the efficacy and safety of suvorexant for insomnia in people with psychiatric disorders.
Moonlighting Proteins and Cardiopathy in the Spatial Response of MCF‐7 Breast Cancer Cells to Tamoxifen
Authors: Alkhanjaf Abdulrab Ahmed M. , Raggiaschi Roberto , Crawford Mark , Pinto Gabriella , Godovac‐Zimmermann Jasminka 
Published: July 2019

BackgroundThe purpose of this study is to apply quantitative high‐throughput proteomics methods to investigate dynamic aspects of protein changes in nucleocytoplasmic distribution of proteins and of total protein abundance for MCF‐7 cells exposed to tamoxifen (Tam) in order to reveal the agonistic and antagonistic roles of the drug.Experimental designThe MS‐based global quantitative proteomics with the analysis of fractions enriched in target subcellular locations is applied to measure the changes in total abundance and in the compartmental abundance/distribution between the nucleus and cytoplasm for several thousand proteins differentially expressed in MCF‐7 cells in response to Tam stimulation.ResultsThe response of MCF‐7 cells to the Tam treatment shows significant changes in subcellular abundance rather than in their total abundance. The bioinformatics study reveals the relevance of moonlighting proteins and numerous pathways involved in Tam response of MCF‐7 including some of which may explain the agonistic and antagonistic roles of the drug.ConclusionsThe results indicate possible protective role of Tam against cardiovascular diseases as well as its involvement in G‐protein coupled receptors pathways that enhance breast tissue proliferation.
L∞‐Algebras of Classical Field Theories and the Batalin–Vilkovisky Formalism
Authors: Jurčo Branislav , Raspollini Lorenzo , Sämann Christian , Wolf Martin 
Published: July 2019

AbstractWe review in detail the Batalin–Vilkovisky formalism for Lagrangian field theories and its mathematical foundations with an emphasis on higher algebraic structures and classical field theories. In particular, we show how a field theory gives rise to an ‐algebra and how quasi‐isomorphisms between ‐algebras correspond to classical equivalences of field theories. A few experts may be familiar with parts of our discussion, however, the material is presented from the perspective of a very general notion of a gauge theory. We also make a number of new observations and present some new results. Most importantly, we discuss in great detail higher (categorified) Chern–Simons theories and give some useful shortcuts in usually rather involved computations.
Biocontrol potential ofMicrobacterium maritypicumSneb159 againstHeterodera glycines
Authors: Zhao Jing , Liu Dan , Wang Yuanyuan , Zhu Xiaofeng , Xuan Yuanhu , Liu Xiaoyu , Fan Haiyan , Chen Lijie , Duan Yuxi 
Published: July 2019

AbstractBACKGROUNDThe soybean cyst nematodeHeterodera glycines(Ichinohe) is the most devastating pathogen affecting soybean production worldwide. Biocontrol agents have become eco‐friendly candidates to control pathogens. The aim of this study was to discover novel biocontrol agents againstH. glycines.RESULTSMicrobacterium maritypicumSneb159, screened from 804 strains, effectively reduced the number of females in field experiments conducted in 2014 and 2015. The stability and efficiency ofH. glycinescontrol by Sneb159 was further assessed in growth chamber and field experiments. Sneb159 decreasedH. glycinespopulation densities, especially the number of females by 43.9%–67.7%. To confirm Sneb159 induced plant resistance, a split‐root assay was conducted. Sneb159 induced local and systemic resistance to suppress the penetration and development ofH. glycines, and enhanced the gene expression ofPR2,PR3b, andJAZ1, involved in the salicylic acid and jasmonic acid pathways.CONCLUSIONThis is the first report ofM. maritypicumSneb159 suppressingH. glycinesinfection. This effect may be the result of Sneb159‐induced resistance. Our study indicates thatM. maritypicumSneb159 is a promising biocontrol agent againstH. glycines. © 2019 Society of Chemical Industry
Review of sensorless control techniques for PMSM drives
Authors: Wang Qiong , Wang Shuanghong , Chen Chuanhai 
Published: July 2019

AbstractPermanent magnet synchronous motor (PMSM) drive systems have been increasingly applied in all kinds of high‐power AC drives because of their inherent advantages of good performance, rapid dynamic response, as well as high reliability and efficiency. Precise control of the system traditionally depends on the shaft encoder, but the presence of the encoder could result in increased cost and volume, reduced reliability, etc. Therefore, the development of sensorless control techniques is important to avoid the above issues by the elimination of the sensor. Based on the running process of the motor, sensorless control techniques can be classified into four categories: initial position detection methods (IPDMs), low‐speed control strategies, mid‐high‐speed control strategies, and full‐speed control strategies. The fundamental principles, their advantages and disadvantages, the control precision, and the application range of these strategies on surface and interior permanent magnet synchronous motors (SPMSMs, IPMSMs) are described in detail in this paper. Finally, the development trend of PMSM sensorless control technologies is discussed. © 2019 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
Vitamin D, Autoimmune Disease and Rheumatoid Arthritis
Authors: Harrison Stephanie R. , Li Danyang , Jeffery Louisa E. , Raza Karim , Hewison Martin 
Published: July 2019

AbstractVitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH)2D3 is expressed by many cells within the immune system and resulting effects include modulation of T cell phenotype to suppress pro-inflammatory Th1 and Th17 CD4+ T cells and promote tolerogenic regulatory T cells. In addition, antigen-presenting cells have been shown to express the enzyme 1α-hydroxylase that converts precursor 25-hydroxyvitamin D3 (25-OHD3) to 1,25-(OH)2D3, so that immune microenvironments are able to both activate and respond to vitamin D. As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA). The aim of this review is to explore the immune activities of vitamin D that impact autoimmune disease, with specific reference to RA. As well as outlining the mechanisms linking vitamin D with autoimmune disease, the review will also describe the different studies that have linked vitamin D status to RA, and the current supplementation studies that have explored the potential benefits of vitamin D for prevention or treatment of RA. The overall aim of the review is to provide a fresh perspective on the potential role of vitamin D in RA pathogenesis and treatment.
Compliance with the ERAS Protocol and 3‐Year Survival After Laparoscopic Surgery for Non‐metastatic Colorectal Cancer
Authors: Pisarska Magdalena , Torbicz Grzegorz , Gajewska Natalia , Rubinkiewicz Mateusz , Wierdak Mateusz , Major Piotr , Budzyński Andrzej , Ljungqvist Olle , Pędziwiatr Michał 
Published: July 2019

AbstractIntroductionEnhanced recovery after surgery (ERAS) pathways have been proven to enhance postoperative recovery, reduce morbidity, and reduce length of hospital stay after colorectal cancer surgery. However, despite the benefits of the ERAS program on short‐term results, little is known about its impact on long‐term results.ObjectiveThe aim of the study was to determine the association between adherence to the ERAS protocol and long‐term survival after laparoscopic colorectal resection for non‐metastatic cancer.Material and MethodologyBetween 2013 and 2016, 350 patients underwent laparoscopic colorectal cancer resection in the 2nd Department of General Surgery, Jagiellonian University Medical College, and were enrolled for further analysis. The relationship between the rate of compliance with the ERAS protocol and 3‐year survival was analyzed according to the Kaplan–Meier method with log‐rank tests. Patients were divided into two groups according to their degree of adherence to the ERAS interventions: Group 1 (109 patients), < 80% adherence, and Group 2 (241 patients), ≥ 80% adherence. The primary outcome was overall 3‐year survival. The secondary outcomes were postoperative complications, length of hospital stay, and recovery parameters.ResultsThe groups were similar in terms of demographics and surgical parameters. The median compliance to ERAS interventions was 85.2%. The Cox proportional model showed that AJCC III (HR 3.28, 95% CI 1.61–6.59, p = 0.0021), postoperative complications (HR 2.63, 95% CI 1.19–5.52, p = 0.0161), and compliance with ERAS protocol < 80% (HR 3.38, 95% CI 2.23–5.21, p = 0.0102) were independent predictors for poor prognosis. Additionally, analysis revealed that adherence to the ERAS protocol in Group 2 with ≥ 80% adherence was associated with a significantly shorter length of hospital stay (6 vs. 4 days, p < 0.0001), a lower rate of postoperative complications (44.7% vs. 23.3%, p < 0.0001), and improved functional recovery parameters: tolerance of oral diet (53.4% vs. 81.5%, p < 0.0001) and mobilization (77.7% vs. 96.1%, p < 0.0001) on the first postoperative day.Conclusions and RelevanceThis study reports an association between adherence to the ERAS protocol and long‐term survival after laparoscopic colorectal resection for non‐metastatic cancer. Lower adherence to the protocol, independent from stage of cancer and postoperative complications, was an independent risk factors for poorer survival rates.
Selective Histological Examination After Cholecystectomy: An Analysis of Current Daily Practice in The Netherlands
Authors: Corten B. J. G. A. , Leclercq W. K. G. , Dejong C. H. , Roumen R. M. H. , Slooter G. D. 
Published: July 2019

AbstractBackgroundThe 2016 Dutch national guidelines on handling of a removed gallbladder for cholelithiasis proposes a selective histopathologic policy (Sel‐HP) rather than routine policy (Rout‐HP). The aim of this study was to determine the current implementation of the present guideline and the daily practice of Sel‐HP.MethodsSurgeons who were engaged in gallbladder surgery in the Netherlands and were involved in local hospitals’ gallbladder protocols completed a questionnaire study regarding gallbladder policy, between December 2017 and May 2018. Data were analyzed using standard statistics.ResultsA 100% response rate was obtained (n = 74). Approximately 64% of all gallbladders (n = 22,500) were examined microscopically. Sixty‐nine (93.2%) hospitals confirmed they were aware of the new guidelines, and 56 (75.7%) knew the guideline was adjusted in favor of Sel‐HP. Half of the hospitals (n = 35, 47.3%) had adopted a Sel‐HP, and 39 (52.7%) a Rout‐HP. Of the 39 hospitals who had a Rout‐HP, 36 were open to a transition to a Sel‐HP although some expressed the need for more evidence on safety or novel guidelines.ConclusionsThe current implementation of the 2016 Dutch guideline advising a selective microscopic analysis of removed gallbladders for gallstone disease is suboptimal. Evidence demonstrating safety and cost‐effectiveness of an on demand histopathological examination will aid in the implementation process.
Cytokine profiling in anti neutrophil cytoplasmic antibody-associated vasculitis: a cross-sectional cohort study
Authors: Hoffmann Johanna Charlotte , Patschan Daniel , Dihazi Hassan , Müller Claudia , Schwarze Katrin , Henze Elvira , Ritter Oliver , Müller Gerhard Anton , Patschan Susann 
Published: July 2019

Abstract
ANCA-associated vasculitides (AAV) are severe diseases, potentially affecting lungs, kidney, and other organs. Nevertheless, risk profiling remains difficult. Aim of the current study was to analyze serological characteristics in AAV. The principal goal was to identify diagnostic markers that potentially allow a more sophisticated risk profiling in AAV. AAV subjects were recruited and evaluated for disease activity, disease stage, medication, and laboratory findings. Serum concentrations of the following parameters were measured: IL-1β, IL-6, IL-17 A, IL-17 F, IL-21, IL-22, IL-23, TNF-α, sCD40L, IL-4, IL-10, IL-25, IL-31, IL-33, and INF-γ. A total number of 62 AAV subjects was included in the study (39 females; 23 males). Forty-five subjects were PR3+, 17 subjects showed ANCA specificity for MPO. The majority of all cytokines fell under the lower detection limit of the assay. Serum IL-10 was higher in both, AAV and SSc as compared to controls; it was also higher in early systemic AAV. Serum IL-33 was elevated in AAV and SSc; in AAV, higher levels were found in non-necrotizing GN and RTX untreated subjects. Serum CD40L was raised in AAV as well; higher concentrations were also found in PR3+ and MPO+ patients and early systemic, generalized, and refractory AAV. IL-10 may potentially serve as a marker of early systemic AAV. IL-33 may help to identify subjects with a higher risk for necrotizing GN in AAV.
Occurrence of Placer Gold in the Marlagalla-Allapatna Areas, Mandya District, Karnataka
Authors: Rajendran R. , Jagadeesan P. , Thirupathi P.V. , Durani Smeer , Rai S.D. , Bhatt A.K. , Zakaulla Syed , Nanda L.K. , Rai A.K. 
Published: July 2019

ABSTRACT
Occurrence of placer gold is reported for the first time in the insitu and colluvial gravels derived from amphibolite/hornblende schist, associated pegmatite and quartz veins of Nagamangala schist belt in Marlagalla –Allapatna areas, Mandya district, Karnataka. Gold occurs in the form of small nuggets, measured up to 3mmx4mm in size and 0.2 gram in weight. The host rock is amphibolite which are intruded by numerous pegmatite and quartz veins. The pegmatites are complex, highly evolved type and contain economic concentration of rare metal bearing minerals viz., columbite-tantalite, beryl and spodumene. Prolonged weathering of these rocks resulted in liberation of gold from host rocks and concentrated in the insitu/eluvial and colluvial gravels. The present finding of gold opens up a new vista for further detailed geological/geochemical exploration to establish and evaluate gold potential in the eluvial, colluvial gravels as well as in the other lithounits of Nagamangala schist belt in Marlagalla-Allapatna areas.
Planktonic Foraminifera from the Neogene Volcaniclastic Sediments of South Andaman Island: Implication on Stratigraphy
Authors: Koley Tarun , Parhi Swetalina , Anju C.S. , Wanjarwadkar K.M. 
Published: July 2019

ABSTRACT
The Neogene volcaniclastic sediments of South Andaman are inter-bedded with shale and siltstone; and occur as a linear band in South Andaman. Planktonic foraminiferal assemblage comprising Globigerinoides quadrilobatus triloba Reuss 1850, G. quadrilobatus altiapertura Bolli 1957, G. quadrilobatus primodius Blow and Banner 1962, G. quadrilobatus sacculifer Brady 1877, G. subquadratus Brönninman & Bermùdez, 1960, G. sicanus de Stefani 1952, Globorotalia foshi peripheroronda Blow & Banner 1966, G. scitula, G. siakensis Leroy 1939, Globorotalia sp.cf. G. opima nana Bolli 1957, G. kugleri Bolli 1957, G. sp. cf. G. scitula Brady, 1882, Globoquadrina cf. lermeuri Akers, 1955, G. altispira globosa Cushman & Jervis, G. dehiscens Chapman, Parr & Collins, 1934 and Globoquadrina sp. from the inter-bedded shale and claystone indicate early Miocene age. Neogene Archipelago Group conformably overlies the Oligocene Andaman Flysch Group without any break in sedimentation. Planktonic foraminiferal assemblage in the lower part of the sequence indicates a level near to Oligo-Miocene boundary. The thick interlayered tuff sequence of South Andaman indicates rejuvenation of arc volcanism in this region during early Miocene.
Micromorphology and Textural Variations in the Ane Ghat Waterfall Tufa Deposits from Upland Deccan Traps and their Genesis
Authors: Ukey Madhuri S. , Pardeshi Ravindrasinh G. 
Published: July 2019

ABSTRACT
Calc tufa associated with waterfalls and rapids from Ane Ghat in the western Deccan Traps have been studied on the basis of their field occurrence, morphology and microtextures. The calc tufas are semi-consolidated and show porous, spongy morphology and occasionally ‘soda straw’ structure. Blue green algae, moss and diatoms are the predominant biotic components of the calc tufa. The growth of such calcifying biota has played a constructive role in building calc tufa deposits at Ane Ghat. Mineralogically, the tufas are made of calcite and contain variable carbonate percentage (53 to 78%). Petrographically, they contain fragments of basalt, devitrified glass, plagioclase, quartz, agate, zeolites, etc. set in a clay-rich and clay-poor micrite. Irregular pore spaces and voids are partially filled with spary calcite lined by thin layers of clay. SEM images of pristine calc tuffa surfaces reveal micro-morphological and textural features that dominantly reflect precipitation. Images of insoluble residue of phases like glass, plagioclase and zeolites indicate some dissolution and corrosive features indicating post depositional diagenetic processes. δ18O V-SMOW values range from 27.03 to 28.92‰ and δ13C V-PDB values of -3.58 to -6.02‰ are recorded for the Ane Ghat samples. The calc tufas were precipitated from waters at paleo-temperatures of 16.3 to 27.1°C. The calc tufa from Ane Ghat represents biological and physico-chemical calcification processes in response to variability in calcium carbonate saturation and water chemistry in temperate to semi-arid climate.
The Impact of Childcare on Poor Urban Women’s Economic Empowerment in Africa
Authors: Clark Shelley , Kabiru Caroline W. , Laszlo Sonia , Muthuri Stella 
Published: July 2019

AbstractDespite evidence from other regions, researchers and policy-makers remain skeptical that women’s disproportionate childcare responsibilities act as a significant barrier to women’s economic empowerment in Africa. This randomized control trial study in an informal settlement in Nairobi, Kenya, demonstrates that limited access to affordable early childcare inhibits poor urban women’s participation in paid work. Women who were offered vouchers for subsidized early childcare were, on average, 8.5 percentage points more likely to be employed than those who were not given vouchers. Most of these employment gains were realized by married mothers. Single mothers, in contrast, benefited by significantly reducing the time spent working without any loss to their earnings by shifting to jobs with more regular hours. The effects on other measures of women’s economic empowerment were mixed. With the exception of children’s health care, access to subsidized daycare did not increase women’s participation in other important household decisions. In addition, contrary to concerns that reducing the costs of childcare may elevate women’s desire for more children, we find no effect on women’s fertility intentions. These findings demonstrate that the impact of subsidized childcare differs by marital status and across outcomes. Nonetheless, in poor urban Africa, as elsewhere, failure to address women’s childcare needs undermines efforts to promote women’s economic empowerment.
Authoritarian resurgence: towards a unified analytical framework
Authors: Cassani Andrea , Tomini Luca 
Published: July 2019

AbstractThis introductory note to the Special Issue ‘Autocracy Strikes Back: Authoritarian Resurgence in the Early 21st Century’ situates this collection of articles in the burgeoning literature on authoritarian resurgence, and illustrates the conceptual terrain on which these articles make their contribution. In this regard, we discuss autocratization, authoritarian resilience, democratic transition failure, and autocracy-to-autocracy transition as processes of regime change representing different ways in which authoritarian resurgence may advance. Relatedly, we clarify how these processes of regime change differ from each other and provide a few basic coordinates to frame their comparative analysis.