bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of Errors in Pediatric Prescriptions and Interventions to Prevent Errors: A Survey of Community Pharmacists
Authors: Brown Sara W. , Oliveri Lauren M. , Ohler Kirsten H. , Briars Leslie 
Published: July 2019

OBJECTIVES Assess the competency of community pharmacists in identifying errors in pediatric prescriptions and to determine how often pharmacists perform interventions known to mitigate the likelihood of error. The study sought to recognize factors that may impact the pharmacist's ability to identify and mediate these errors, and to detect barriers that limit the role of the pharmacist pediatric patient care.
METHODS A survey was distributed through the University of Illinois at Chicago College of Pharmacy Alumni Network and the Illinois Pharmacists Association email listservs. Pharmacists practicing in a retail setting within the last 5 years were included. Three prescription scenarios for commonly used pediatric medications with corresponding questions were created to assess a pharmacist's ability to identify errors. Demographics pertaining to the pharmacist and the practice site, as well as information about dispensing practices, were collected. Logistic regression was used to identify factors that might impact the pharmacists' ability to identify errors.
RESULTS One hundred sixty-one respondents began the survey and 138 met inclusion criteria. In 15% to 59% of scenario-based questions, pharmacists did not appropriately identify errors or interventions that would decrease the likelihood of error. Correct identification of doses was associated with total prescription volume in one scenario and with pediatric prescription volume in another scenario. Pharmacists did not consistently label prescriptions for oral liquids in milliliters or dispense oral syringes. Barriers to pharmacist involvement included availability and interest of the caregiver, ability to contact prescriber, and pharmacy staffing.
CONCLUSION Community pharmacists did not consistently identify medication errors or use interventions known to mitigate error risk.
Ibn ʿArabī y la residencia de los Ṭāʾī en La Alberca (Murcia)
Authors: Pocklington Robert 
Published: July 2019

La historia medieval de La Alberca, población situada a 4 km al sur de Murcia (España), es actualmente una gran desconocida, a pesar de su insigne pasado argárico, ibérico, romano y visigótico de la ladera meridional de la Huerta que no tuvo continuidad en la época árabe y bajomedieval, y con la destrucción de lo que se llamaba Eio tras la fundación de Murcia en el 825 parece marcar el fin de un período glorioso. En el verano de 1165, cuando nació Ibn ʿArabī, el reino mardanīší de Murcia vivía sus últimos años de calma y prosperidad, pues aún controlaba un vasto territorio que se extendía prácticamente hasta Córdoba, Pero por esas mismas fechas los almohades ya estaban preparando la primera incursión importante de su larga campaña para conquistar Murcia. La Alberca, tras esta conquista, dejo de ser importante hasta principios del siglo XVII que volvió a asomar la cabeza cuando Gabriel Dávalos Fajardo compró el mayorazgo a Felipe IV y la convirtió en villa con el nombre de La Alberca de las Torres. En el presente artículo queremos hacer una revisión sobre qué había en La Alberca y su entorno durante la mayor parte de la época islámica y los primeros siglos cristianos, para ello recurriremos al linaje de Muḥyī l-Dīn Ibn al-ʿArabī, íntimamente unido —como mostraremos— al pasado de esta población, lo cual nos ayudará a reconstruir en parte su historia durante este período. Pues en el nombre completo de Ibn ‘Arabī encontramos la nisba tribal al-Ṭāʾī al-Ḥātimī, cuyo adjetivo gentilicio ṭāʾī sitúa los orígenes tribales de Ibn ʿArabī en la otrora poderoso clan árabe de los Ṭayyiʾ. Y hallamos, precisamente, que Murcia fue el lugar de origen de entre el 30% y 40% de los autores andalusíes ṭāʾíes, y que pudo haberse convertido en el solar principal de la tribu Ṭayyiʾ en al-Andalus, lo cual confirma el dato de al-Maqqarī de que “la residencia de los Ṭayyiʾ (Manzil Ṭayyiʾ) en al-Andalus se encontraba en Murcia”, ya que, además la expresión “Manzil Tayyi’ se convirtió en un topónimo patrimonial y fue adoptado por los primeros pobladores castellanos de Murcia como Mezlatay, nombre que, como veremos, podemos identificar con la zona de la Alberca. Además, Mezlatay llegó a ser un importante lugar hasta el punto de que Alfonso X, después de cederlo en un primer momento a la ciudad de Cartagena, lo recuperó para entregárselo al hijo del rey Ibn Hud de Murcia.
L’innocence du romancier : Orhan Pamuk ouvre son art
Authors: Hamel Yan 
Published: July 2019

Cet article se penche sur Le romancier naïf et le romancier sentimental, transposition écrite des conférences de Charles Eliot Norton prononcées par Orhan Pamuk à l’Université Harvard en 2009, ainsi que sur D’autres couleurs, recueil d’essais portant en partie sur l’art du roman et l’oeuvre de romanciers importants tels que Sterne, Dostoïevski, Tolstoi, Mann, etc. Il s’agit de montrer comment la pensée de Pamuk sur l’art du roman est profondément scindée, mise en tension par une série de contradictions irrésolues. Par exemple, l’auteur, qui veut présenter le roman comme un genre autosuffisant — capable de s’engendrer et de se penser lui-même —, se montre néanmoins féru de théorie littéraire et désireux d’exposer ses idées dans des genres non fictionnels. L’article en vient à proposer une lecture montrant comment le dynamisme propre au genre romanesque naît justement de cette instabilité et de cette irrésolution qui se laissent lire dans les méandres de la pensée élaborée par le Prix Nobel de littérature.
Empathy in Medicine Osteopathic and Allopathic Physician Interpersonal Manner, Empathy, and Communication Style and Clinical Status of Their Patients: A Pain Registry–Based Study
Authors: Licciardone John C. , Schmitt Monika E. , Aryal Subhash 
Published: July 2019

Abstract

Context
Comparisons of osteopathic physicians (ie, DOs) and allopathic physicians (ie, MDs) on interpersonal manner, including empathy and communication style, have been limited by such methodologic issues as self-assessment and a focus on medical students rather than practicing physicians.

Objective
To compare perceptions of the interpersonal manner, empathy, and communication style of DOs and MDs and corresponding clinical measures reported by their patients.

Methods
A cross-sectional study of adults with subacute or chronic low back pain was conducted within the PRECISION Pain Research Registry from April 2016 through December 2018. A total of 313 patients having their physician for 1 year or longer reported sociodemographic and clinical characteristics, including use of nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids for low back pain. Using validated research instruments, they also reported perceptions of their physician's interpersonal manner, empathy, and communication style and clinical measures of pain catastrophizing, pain self-efficacy, low back pain intensity, back-related disability, and deficits in quality of life relating to sleep disturbance, pain interference with activities, anxiety, depression, and low energy/fatigue.

Results
Patients treated by DOs were less likely to be using NSAIDs (odds ratio [OR], 0.60; 95% CI, 0.36-0.997) or opioids (OR, 0.57; 95% CI, 0.32-0.998) than patients treated by MDs. Patients treated by DOs reported lesser pain catastrophizing (mean, 12.5; 95% CI, 10.1-15.0 for DOs vs 18.1; 95% CI, 16.3-19.9 for MDs; P<.001) and greater pain self-efficacy (mean, 39.5; 95% CI, 36.3-42.8 for DOs vs 35.3; 95% CI, 33.4-37.3 for MDs; P=.03). Correspondingly, patients treated by DOs reported lesser back-related disability (mean, 11.2; 95% CI, 9.9-12.5 for DOs vs 13.5; 95% CI, 12.8-14.3 for MDs; P=.002) and a trend toward lesser deficits in quality of life. Patients reported more favorable perceptions of DOs on interpersonal manner (mean, 4.3; 95% CI, 4.2-4.5 for DOs vs 4.0; 95% CI, 3.9-4.2 for MDs; P=.01) and empathy (mean, 41.2; 95% CI, 39.1-43.3 for DOs vs 38.0; 95% CI, 36.5-39.5 for MDs; P=.02).

Conclusion
The mechanisms underlying lesser use of NSAIDs and opioids, superior clinical status measures, and more favorable perceptions of physician interpersonal manner and empathy reported by patients treated by DOs warrant further investigation.
Trajectories of change after a health-education program in Japan: decay of impact in anxiety, depression, and patient-physician communication
Authors: Park Min Jeong , Green Joseph , Jung Hun Sik , Park Yoon Soo 
Published: July 2019

BackgroundHealth education can benefit people with chronic diseases. However, in previous research those benefits were small, and reinforcement to maintain them was not effective. A possible explanation is that the benefitsappearedto be small and reinforcementappearedto be ineffective because those analyses mixed data from two latent groups: one group of people who needed reinforcement and one group of people who did not. The hypothesis is that mixing the data from those two different groups caused the true effects to be “diluted.”MethodsTo test that hypothesis we used data from the Chronic Disease Self-Management Program in Japan, focusing on anxiety, depression, and patient-physician communication. To identify latent trajectories of change after the program, we used growth-mixture modeling. Then, to find out which baseline factors were associated with trajectory-group membership, we used logistic regression.ResultsGrowth-mixture modeling revealed two trajectories—two groups that were defined by distinct patterns of change after the program. One of those patterns was improvement followed by backsliding: decay of impact. On anxiety and depression the decay of impact was large enough to be clinically important, and its prevalence was as high as 50%. Next, logistic regression analysis revealed that being in the decay-of-impact group could be predicted from multimorbidity, low self-efficacy, and high scores on anxiety or depression at baseline. In addition, one unexpected finding was an association between multimorbidity andbetterpatient-physician communication.ConclusionsThese results support the hypothesis that previous findings (i.e.,apparentlysmall effect sizes andapparentlyineffective reinforcement) actually reflect “dilution” of large effects, which was caused by mixing of data from distinct groups. Specifically, there was one group with decay of impact and one without. Thus, evaluations of health education should include analyses of trajectory-defined groups. These results show how the group of people who are most likely to need reinforcement can be identified even before the educational program begins. Extra attention and reinforcement can then be tailored. They can be focused specifically to benefit the people with the greatest need.
Diversity, ecology and distribution of benthic diatoms in thermo-mineral springs in Auvergne (France) and Sardinia (Italy)
Authors: Lai Giuseppina G. , Beauger Aude , Wetzel Carlos E. , Padedda Bachisio M. , Voldoire Olivier , Lugliè Antonella , Allain Elisabeth , Ector Luc 
Published: July 2019

This study investigated and compared the diatom flora from thermo-mineral springs in Auvergne (France) and Sardinia (Italy). Samples were collected from rock/cobbles and fine sediments in 16 springs between January 2015 and March 2017. A total of 207 taxa (59 genera) were found. Multivariate analyses revealed significant differences in species composition and abundance among diatom assemblages both within each geographic region and between Auvergne and Sardinia (global R = 0.516; p = 0.002), suggesting the importance of local and climatic factors in species distribution. Based on abundance and common occurrence in multiple sites, some taxa can be considered more representative of springs in each region: Crenotia thermalis for Auvergne and Lemnicola exigua, Nitzschia amphibia, N. inconspicua and Rhopalodia operculata for Sardinia. pH, conductivity and HCO3− were the most significant environmental variables for diatom assemblages. Our results highlight the high heterogeneity of these spring systems. Future taxonomic insights can be useful to define the identity of some abundant and dominant taxa not identified at the species level in this study. Their identification is a crucial step for a more precise ecological characterization and comparison of these peculiar spring systems.
The aridity index governs the variation of vegetation characteristics in alpine grassland, Northern Tibet Plateau
Authors: Liu Biying , Sun Jian , Liu Miao , Zeng Tao , Zhu Juntao 
Published: July 2019

The vegetation dynamic (e.g., community productivity) is an important index used to evaluate the ecosystem function of grassland ecosystem. However, the critical factors that affect vegetation biomass are disputed continuously, and most of the debates focus on mean annual precipitation (MAP) or temperature (MAT). This article integrated these two factors, used the aridity index (AI) to describe the dynamics of MAP and MAT, and tested the hypothesis that vegetation traits are influenced primarily by the AI. We sampled 275 plots at 55 sites (five plots at each site, including alpine steppe and meadow) across an alpine grassland of the northern Tibet Plateau, used correlation analysis and redundancy analysis (RDA) to explore which key factors determine the biomass dynamic, and explained the mechanism by which they affect the vegetation biomass in different vegetation types via structural equation modelling (SEM). The results supported our hypothesis, in all of the environmental factors collected, the AI made the greatest contribution to biomass variations in RDA , and the correlation between the AI and biomass was the largest (R = 0.85, p < 0.05). The final SEM also validated our hypothesis that the AI explained 79.3% and 84.4% of the biomass variations in the alpine steppe and the meadow, respectively. Furthermore, we found that the soils with higher carbon to nitrogen ratio and soil total nitrogen had larger biomass, whereas soil organic carbon had a negative effect on biomass in alpine steppe; however, opposite effects of soil factors on biomass were observed in an alpine meadow. The findings demonstrated that the AI was the most critical factor affecting biomass in the alpine grasslands, and different reaction mechanisms of biomass response to the AI existed in the alpine steppe and alpine meadow.
Predicting the potential distribution of the Asian citrus psyllid,Diaphorina citri(Kuwayama), in China using the MaxEnt model
Authors: Wang Rulin , Yang Hua , Luo Wei , Wang Mingtian , Lu Xingli , Huang Tingting , Zhao Jinpeng , Li Qing 
Published: July 2019

BackgroundCitrus huanglongbing (HLB) is a destructive disease of citrus and a major threat to the citrus industry around the world. This disease accounts for substantial economic losses in China every year.Diaphorina citriKuwayama is one of the major vectors by which citrus HLB is spread under natural conditions in China. Research is needed to identify the geographic distribution ofD. citriand its major areas of occurrence and to formulate measures for early warning, monitoring, and control of this pest and citrus HLB.MethodsIn this study, the ecological niche modelling software MaxEnt (maximum entropy model) was combined with ArcGIS (a geographic information system) to predict the potential geographic distribution ofD. citriin China. Key environmental factors and the appropriate ranges of their values were also investigated.ResultsOur results show that the training data provided a good forecast (AUCmean= 0.988). The highly suitable areas forD. citriin China are mainly concentrated to the south of the Yangtze River, and the total area is 139.83 × 104km2. The area of the moderately suitable areas is 27.71 × 104km2, with a narrower distribution than that of the highly suitable area. The important environmental factors affecting the distribution ofD. citriwere min temperature of coldest month, mean temperature of coldest quarter, precipitation of wettest quarter, mean temperature of warmest quarter, precipitation of warmest quarter, max temperature of warmest month, and temperature seasonality. These results provide a valuable theoretical basis for risk assessments and control ofD. citri.DiscussionThe predicted results showed that there were highly suitable areas forD. citriin Chongqing, Hubei, Anhui, and Jiangsu. Therefore, the possibility exists for the further spread ofD. citriin China in the future. Extreme temperature variables, especially the min temperature of the coldest month, play an important role in the distribution ofD. citriand are most closely related to the distribution ofD. citri.
Difficulties in the Incorporation of Augmented Reality in University Education: Visions from the Experts
Authors: Barroso-Osuna Julio , Gutiérrez-Castillo Juan Jesús , Llorente-Cejudo Mªdel Carmen , Ortiz Rubicelia Valencia 
Published: July 2019

Abstract
“Augmented reality” (AR) is presented as technology that harmonizes, in real time and with user collaboration, digital information with physical information through different technological supports. Such are AR possibilities, that when it is incorporated into teaching, students show high satisfaction rates and positive attitudes for its use, but at the same time, a series of limitations and obstacles can be noticed. As an attempt to investigate the technical, curricular and organizational difficulties of AR incorporation in training contexts, an instrument “AR obstacle questionnaire” (CORA) was designed, which in turn was administered to a total of 264 subject experts for validation through the Delphi method, subsequently applying the “K coefficient” (
$${\rm{K = }}{1 \over 2}$$
Kc (knowledge coefficient) + Ka (argumentation coefficient)), selecting those experts who obtained a ≥ 0,8 score in the coefficient. Among the results obtained in the study we manage to point out the main obstacles involving AR implementation into university education: the lack of teacher training and improvement, the few educational experiences found, lack of conceptual foundation, limited educational research and lack of institutional support.
Com-educational Platforms: Creativity and Community for Learning
Authors: Sánchez-López Iván , Pérez-Rodríguez Amor , Fandos-Igado Manuel 
Published: July 2019

Abstract
Education is at a time of redefinition and transformation, in line with an era characterized by considerable technological development and profound social changes. One would expect it to be accompanied by a media context in which narrative models are transformed by the impact of digitalization, affecting student-teacher interactions. However, it has been observed that the media usage of an entire generation emphasizes the gap between formal education and young people’s everyday digital life. Within this framework, and at the international level, a series of innovative pedagogical proposals have emerged, which approach education from the field of communication: Minecraft Education, NFB Education, Educ’Arte, Scratch and 7 de Cinema. We have called them com-educational platforms, because of their investment in the education-communication vector, based on an educommunicative idea. The proposed study implements a multimodal discourse analysis (MDA) to gain an in-depth knowledge of its characteristics. Beyond their individual idiosyncrasies, our analysis reveals a common central feature: the placement of community-creativity combination as the core phenomenon for learning.
Cramér-Rao Bound of Direction Finding Using Uniform Arc Arrays
Authors: Nyokabi Veronicah , Kitavi Dominic Makaa , Ngari Cyrus Gitonga 
Published: July 2019

Direction-of-Arrival estimation accuracy using arc array geometry is considered in this paper.There is a scanty use of Uniform Arc Array (UAA) in conjunction with Cramer-Rao bound (CRB)for Direction-of-Arrival estimation. This paper proposed to use Uniform Arc Array formed from a considered Uniform Circular Array (UCA) in conjunction with CRB for Direction-of-Arrival estimation. This Uniform Arc Array is obtained by squeezing all sensors on the Uniform Circular Array circumference uniformly onto the Arc Array. Cramer-Rao bounds for the Uniform Arc Array and that of the Uniform Circular Array are derived. Comparison of performance of the Uniform Circular Array and Uniform Arc Array is done. It was observed that Uniform Arc Array has better estimation accuracy as compared to Uniform Circular Array when number of sensors equals four and ve and azimuth angle ranging between $$\frac{\pi}{9}~ and ~\frac{7}{18}\pi~ and~ also ~\frac{10}{9}\pi ~and ~\frac{25}{18}\pi$$. However, UCA and UAA have equal performance when the number of sensors equals three and the azimuth angle ranging between 0 and 2π. UCA has better estimation accuracy as compared to UAA when the number of sensors equals four and ve and the azimuth angle ranging between
$$\frac{\pi}{2} ~and~ \pi ~and ~also~ \frac{3}{2}\pi ~and~ 2\pi$$
Wafer‐Scale Fabrication of Conducting Polymer Hydrogels for Microelectrodes and Flexible Bioelectronics
Authors: Kleber Carolin , Lienkamp Karen , Rühe Jürgen , Asplund Maria 
Published: July 2019

AbstractFuture‐oriented directions in neural interface technologies point towards the development of multimodal devices that combine different functionalities such as neural stimulation, neurotransmitter sensing, and drug release within one platform. Conducting polymer hydrogels (CPHs) are suggested as materials for the coating of standard metal electrodes to add functionalities such as local delivery of therapeutic drugs. However, to make such coatings truly useful for multimodal devices, it is necessary to develop process technologies that allow the micropatterning of CPHs onto selected electrode sites. In this study, a wafer‐scale fabrication procedure is presented, which is used to coat the CPH, based on the hydrogel P(DMAA‐co‐5%MABP‐co‐2,5%SSNa) and the conducting polymer poly(3,4‐ethylenedioxythiophene) (PEDOT), onto flexible neural probes. The resulting material has favorable properties for the generation of recording electrodes and in addition offers a convenient platform for biofunctionalization. By controlling the PEDOT content within the hydrogel matrix, charge injection limits of up to 3.7 mC cm−2 are obtained. Long‐term stability is tested by immersing coated samples in phosphate‐buffered saline solution at 37 °C for 1 year. Non‐cytotoxicity of the coatings is confirmed with a direct cell culture test using a fluorescent neuroblastoma cell line.
SnTe@MnO2‐SP Nanosheet–Based Intelligent Nanoplatform for Second Near‐Infrared Light–Mediated Cancer Theranostics
Authors: Zhang Hanjie , Zeng Weiwei , Pan Chao , Feng Liwen , Ou Meitong , Zeng Xiaowei , Liang Xin , Wu Meiying , Ji Xiaoyuan , Mei Lin 
Published: July 2019

AbstractNear infrared light, especially the second near‐infrared light (NIR II) biowindows with deep penetration and high sensitivity are widely used for optical diagnosis and phototherapy. Here, a novel kind of 2D SnTe@MnO2‐SP nanosheet (NS)‐based nanoplatform is developed for cancer theranostics with NIR II‐mediated precise optical imaging and effective photothermal ablation of mouse xenografted tumors. The 2D SnTe@MnO2‐SP NSs are fabricated via a facile method combining ball‐milling and liquid exfoliation for synthesis of SnTe NSs, and surface coating MnO2 shell and soybean phospholipid (SP). The ultrathin SnTe@MnO2‐SP NSs reveal notably high photothermal conversion efficiency (38.2% in NIR I and 43.9% in NIR II). The SnTe@MnO2‐SP NSs inherently feature tumor microenvironment (TME)‐responsive biodegradability, and the main metabolite TeO32− shows great antitumor effect, coupling synergetic chemotherapy for cancer. Moreover, the SnTe@MnO2‐SP NSs also exhibit great potential for fluorescence, photoacoustic (PA), and photothermal imaging agents in the NIR II biowindow with much higher resolution and sensitivity. This is the first report, as far as is known, with such an inorganic nanoagent setting fluorescence/PA/photothermal imaging and photothermal therapy in NIR II biowindow and TME‐responsive biodegradability rolled into one, which provide insight into the clinical potential for cancer theranostics.