bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical management of eosinophilic esophagitis – a nationwide survey among gastroenterologists in Germany
Authors: Miehlke Stephan , von Arnim Ulrike , Schlag Christoph , Frieling Thomas , Madisch Ahmed , Loibl Rudolf , Mainz Dagmar , Labenz Joachim 
Published: June 2019

Abstract
Background Eosinophilic esophagitis (EoE) is an increasingly recognized immune-mediated esophageal disease and a common cause for dysphagia and food bolus obstruction. The aim of this study was to evaluate the current clinical management of EoE among adult gastroenterologists in Germany.
Methods We performed a cross-sectional study of 1393 adult gastroenterologists using a questionnaire containing 22 questions to general, diagnostic, and therapeutic aspects of EoE. The self-administered online survey was conducted between November 2017 and February 2018. Data capture and analysis was performed using SurveyMonkey.
Results The overall responder rate was 29.6 %. More than half of the responders (54.9 %) felt to observe a significant increase of EoE patients. The EREFS score was mostly either unknown (44.3 %) or not routinely used (52.2 %). If EoE was suspected, most responders obtained multiple esophageal biopsies (n = 3 – 4: 35.7 %; n > 4: 61.6 %). The preferred primary treatment was proton pump inhibitors (PPI) in 37.2 % and topical steroids in 35.0 % of responders. PPI regimens were highly diverse, with only half of responders using high-dose PPI regimens. Allergy testing was often initiated (always 25.4 %, sometimes 48.9 %). The most common dietary therapy was 6-food elimination diet (52 %), followed by allergy test-directed diets (16 %) and 2-food elimination diet (16.5 %). The majority of responders indicated a need for long-term treatment (i. e., 23 % of responders in > 50 % their patients and 47.7 % of responders in 25 – 50 % of their patients).
Conclusions Among gastroenterologists in Germany, substantial variation in the adherence to published EoE guidelines appears to exist. This indicates the need for intensified education and national guidelines in order to optimize and harmonize the clinical management of EoE patients.
Zum Problem der Häufigkeitsbestimmung von
Intergeschlechtlichkeit und Varianten der Geschlechtsentwicklung: Eine
Übersichtsarbeit
Authors: Hauck Lena , Richter-Appelt Hertha , Schweizer Katinka 
Published: June 2019

Zusammenfassung
Einführung Körperliche Geschlechtsentwicklungen, die auf chromosomaler,
gonadaler und/oder anatomischer Ebene untypisch verlaufen, werden als
Intergeschlechtlichkeit, Varianten der Geschlechtsentwicklung, Intersex,
Intersexualität, Variationen der körpergeschlechtlichen Merkmale und Störungen
der Geschlechtsentwicklung bezeichnet. Sie sind alternative Oberbegriffe für
eine Reihe verschiedener Besonderheiten der somatosexuellen Entwicklung, für die
in der Literatur unterschiedliche Angaben über deren Häufigkeiten kursieren.
Forschungsziele Der Beitrag präsentiert eine Übersicht über aktuelle
Angaben zur Häufigkeit und identifiziert Faktoren, welche die Festlegung einer
Zahl zur Inzidenz bzw. Prävalenz von Varianten der Geschlechtsentwicklung
erschweren.
Methoden Es wurde eine Literaturrecherche in den Datenbanken
Medline, Web of Science und PsycINFO durchgeführt.
Dabei wurden englisch- und deutschsprachige Studien von 2000 bis 2017 erfasst,
die sich mit der Inzidenz von Varianten der körpergeschlechtlichen Entwicklung
beschäftigen. Aus den Ergebnissen wurden relevante Treffer ausgewählt, anhand
derer aktuelle Zahlen zur Häufigkeit, unterschiedliche Methoden der
Häufigkeitserhebung sowie Probleme bei der Ermittlung der Zahlen
herausgearbeitet wurden.
Ergebnisse Die analysierten Studien geben Zahlen zwischen 0.018 % und 2.1
% bzw. 3.8 % aller Geburten als Gesamthäufigkeit von Varianten der
Geschlechtsentwicklung bzw. des urogenitalen Systems an. Diese hängen stark von
der Definition und den eingeschlossenen Formen ab. Die Seltenheit einiger Formen
und die kritikwürdigen Untersuchungsmethoden erschweren die Erhebung belastbarer
Ergebnisse.
Schlussfolgerung In der Forschung zur Intergeschlechtlichkeit sollte eine
transparente, respekvolle und präzise Sprache als Grundlage für einen
konstruktiven Diskurs über geschlechtliche Vielfalt eingesetzt werden, auch um
Kooperationsprojekte zu stärken. Die angenommene Dunkelziffer der nicht
erfassten oder diagnostizierten Fälle sollte nicht unterschätzt werden.
Zinkmangel als Ursache eines „Dekubitus“ beim Frühgeborenen?
Authors: Asselborn Jana Rabea , Thayssen Maike , Lehmberg Kai , Apostolidou Sofia , Singer Dominique 
Published: June 2019

ZusammenfassungFrühgeborene haben ein erhöhtes Risiko, einen Zinkmangel zu erleiden, da bedingt durch die fehlende intrauterine Reifung die Zinkspeicher in der Leber nicht gefüllt werden können. Bei einem eutrophen weiblichen Frühgeborenen von 25+5 Schwangerschaftswochen zeigten sich ab dem 14. Lebenstag ein perinealer und perianaler „Dekubitus“. Zahlreiche lokale Therapieversuche blieben erfolglos. Die Diagnostik erbrachte einen erniedrigten Serum-Zinkspiegel, sodass mit einer Substitution begonnen wurde. Bereits nach wenigen Tagen begannen die Defekte zu heilen und waren nach drei Wochen vollständig abgeheilt. Trotz regulären Nahrungsaufbaus mit Formula-Nahrung war der Zinkbedarf in diesem Fall vermutlich aufgrund unvollständiger Resorption nicht gedeckt worden. Der Fall macht auf eine latente Unterversorgung von Frühgeborenen mit Zink aufmerksam und unterstreicht die Notwendigkeit von Kontrollen, besonders bei entsprechenden Hautsymptomen.
Do the New Hydrophilic Surface Have Any Influence on Early Success Rate and Implant Stability during Osseointegration Period? Four-Month Preliminary Results from a Split-Mouth, Randomized Controlled Trial
Authors: Tallarico Marco , Baldini Nicola , Martinolli Matteo , Xhanari Erta , Kim Yong-Jin , Cervino Gabriele , Meloni Silvio Mario 
Published: June 2019

Abstract
Objective The objective of this study is to compare the implant stability of Hiossen ET III implants with its new hydrophilic (NH) surface and Hiossen ET III implants with the sandblasted and acid-etched (SA) surface.
Materials and Methods Patients required at least two teeth to be rehabilitated with a fixed, implant-supported restoration, consecutively enrolled. Patients randomly received SA surface implants (SA group) or SA implants with a newly developed bioabsorbable apatite nanocoating (NH group). Outcome measures were implant and prosthetic survival rate, complications, insertion torque, and implant stability quotient (ISQ) measured at implant placement and every week up to 8 weeks after implant placement. Comparison between groups was made by unpaired t-test, while the comparison between each follow-up will be made by paired t-tests to detect any change during the follow-up. Complications and failures were compared using Fisher's exact test.
Results A total of 14 patients were treated with 28 implants (14 SA and 14 NH). No implant and prosthesis failed 4 months after implant placement. No complications were experienced. At the 2nd week after implants placement, two implants in the SA group showed discontinuous measurements versus none in the NH group (p = 0.4815). Implants unscrewed during ISQ measurements and were rescrewed. Data recording stopped for 6 weeks. Both implants osseointegrated without any further complication. The NH implants did not show physiological ISQ decrease between 2nd and 4th week after implant placement, showing a more even pattern of ISQ values compared with SA implants (77.1 ± 4.6 vs. 72.9 ± 11.5; difference: 4.2 ± 12.1; p = 0.258). High ISQ values were found in both groups at each time point.
Conclusions NH implants are a viable alternative to SA surface, as they seem to avoid the ISQ drop during the remodeling phase.
Marginal Gap Evaluation of Metal Onlays and Resin Nanoceramic Computer-Aided Design and Computer-Aided Manufacturing Blocks Onlays
Authors: Abdul Hamid Nor Faharina , Wan Bakar Wan Zaripah , Ariffin Zaihan 
Published: June 2019

Abstract
Objective This study was carried out to assess and compare the marginal gap of conventionally used metal onlays and new resin nanoceramic (RNC) (Lava Ultimate block) onlays.
Materials and Methods This is an in vitro study using two extracted sound human mandibular molars. One tooth was prepared to receive the metal onlays and another one for the RNC onlays which were fabricated using the computer-aided design and computer-aided manufacturing (CAD/CAM) technology. Twelve metals and 12 ceramic onlays were fabricated before they were placed at their respective preparation and examined under the Leica stereomicroscope, M125C (Leica Microsystems, Wetzlar, Germany) for a marginal analysis. The gap width was measured at 10 predefined landmarks which included 3 points on the buccal and lingual surfaces each and 2 points each on the mesial and distal surfaces, respectively.
Statistical Analysis Mann–Whitney post hoc test was used for statistical analysis (P ≤ 0.05).
Results Overall, the RNC onlays showed significant lower marginal gap with the exception of the landmarks 5 and 6 (on distolingual) and no significant difference at landmark 7 (on midlingual). It was observed that the marginal gap were all within the clinically acceptable limit of 120 μm.
Conclusions Based on the results obtained, it can be concluded that the RNC CAD/CAM onlays are a promising alternative to the metal onlays.
Follow up of Patients with Eagle-Barett (Prune Belly) Syndrome Treated with Single-Stage Abdominoplasty and Total Genitourinary Tract Reconstruction
Authors: Fernández Nicolás , Ortiz Ana María , Iregui Juan David , Estrada Andrea , Rojas Angeline , Niño Jaime Pérez 
Published: June 2019

Abstract
Introduction The Prune Belly Syndrome (PBS) is the deficiency or congenital hypoplasia of the abdominal muscles accompanied with disorders of the urinary tract. The surgical treatment for the uropathy of the PBS seeks to correct the anatomical defects that induce damage to the urinary tract, including the improvement of the bladder emptying. The correction of the abdominal wall defect must be considered as an important part of the treatment.
Objective To describe of the most relevant clinic characteristics and outcomes of a group of eight patients with PBS managed with abdominoplasty and reconstructive urologic surgery.
Methods Retrospective review of the medical charts of patients with PBS at Hospital Universitario San Ignacio, Hospital Militar Central of Bogotá, Clinica Infantil Colsubsidio and Fundación Oftalmológica Ardila Lulle of Bucaramanga, (Colombia) that were managed with reconstructive surgery of the urinary tract and Monfort technique abdominoplasty (between 2006 and 2016) by one of the authors (JPN). The evaluated variables included: phenotypic appearance, renal function, bowel movements, and urinary tract infection (UTI) episodes. These variables as well as the abdominal wall aspect, were evaluated postoperatively.
Results There were 11 patients identified with PBS between 2006 and 2016. Eight (8) of them underwent reconstructive urologic surgery, orchidopexy and Monfort technique abdominoplasty. After the procedures, none of the patients presented deterioration of the renal function, and they reported a better quality of the stools according to the Bristol scale; there were also less episodes of UTI. The phenotypic aspect of the abdominal wall was qualified as satisfactory in all cases.
Conclusions Reconstructive urologic surgery and abdominoplasty in patients with PBS is an excellent choice of management that reduces the number of UTIs, improves bowel movements according to the Bristol scale, and preserves the renal function. This management approach also improves the phenotypic aspect of the abdominal wall. All of this leads to higher survival rate and better quality of life.
Thorium distribution on the Moon: new insights from Chang’E-2 gamma-ray spectrometer*
Authors: Zhu Meng-Hua , Chang Jin , Ma Tao 
Published: June 2019

AbstractWe present the thorium distribution on the lunar surface derived from observations by theChang’E-2gamma-ray spectrometer (CE-2GRS). This new map shows a similar thorium distribution to previous observations. In combination with this new thorium map and impact cratering model, we investigate the origination of thorium on the Moon’s highlands, which was previously thought to be contributed from Imbrium ejecta. We found that the Imbrium ejecta has a small contribution (∼20%–30%) to the thorium on the lunar highlands but most thorium is likely to be indigenous before the deposition of the Imbrium ejecta. This new thorium map also confirms that the eastern highlands have a relatively higher thorium concentration than the western highlands. We propose that the thin crust and large basins on the eastern highlands are responsible for this difference in thorium.
Strange quark star in dilaton gravity
Authors: Peivand Alireza , Naficy Kazem , Bordbar Gholam Hossein 
Published: June 2019

Abstract
In this work, we first obtain the hydrostatic equilibrium equation in dilaton gravity. Then, we examine some of the structural characteristics of a strange quark star in dilaton gravity in the context of Einstein gravity. We show that the variations of dilaton parameter do not affect the maximum mass, but variations in the cosmological constant lead to changes in the structural characteristics of the quark star. We investigate the stability of strange quark stars by applying the MIT bag model with dilaton gravity. We also provide limiting values for the dilaton field parameter and cosmological constant. We also study the effects of dilaton gravity on the other properties of a quark star such as the mean density and gravitational redshift. We conclude that the last reported value for the cosmological constant does not affect the maximum mass of a strange quark star.
Properties of filaments in solar cycle 20-23 from McIntosh Archive
Authors: Mazumder Rakesh 
Published: June 2019

Abstract
A filament is a cool, dense structure suspended in the solar corona. The eruption of a filament is often associated with a coronal mass ejection (CME), which has an adverse effect on space weather. Hence, research on filaments has attracted much attention in the recent past. The tilt angle of active region (AR) magnetic bipoles is a crucial parameter in the context of the solar dynamo, which governs the conversion efficiency of the toroidal magnetic field to poloidal magnetic field. Filaments always form over polarity inversion lines (PILs), so the study of tilt angles for these filaments can provide valuable information about generation of a magnetic field in the Sun. We investigate the tilt angles of filaments and other properties using McIntosh Archive data. We fit a straight line to each filament to estimate its tilt angle. We examine the variation of mean tilt angle with time. The latitude distribution of positive tilt angle filaments and negative tilt angle filaments reveals that there is a dominance of positive tilt angle filaments in the southern hemisphere and negative tilt angle filaments dominate in the northern hemisphere. We study the variation of the mean tilt angle for low and high latitudes separately. Investigations of temporal variation with filament number indicate that total filament number and low latitude filament number vary cyclically, in phase with the solar cycle. There are fewer filaments at high latitudes and they also show a cyclic pattern in temporal variation. We also study the north-south asymmetry of filaments with different latitude criteria.
The morphology, kinematics and metallicity of blue-core galaxies
Authors: Chen Yong-Yun , Chen Yan-Mei , Gu Qiu-Sheng , Shi Yong , Bing Long-Ji , Yu Xiao-Ling 
Published: June 2019

Abstract
We select 107 blue-core galaxies from the MaNGA survey, studying their morphology, kinematics as well as the gas-phase metallicity. Our results are as follows: (i) In our sample, 26% of blue-core galaxies have decoupled gas-star kinematics, indicating external gas accretion; 15% have bar-like structure and 8% show post-merger features, such as tidal tails and irregular gas/star velocity field. All these processes/features, such as accreting external misaligned gas, interaction and bar, can trigger gas inflow. Thus the central star-forming activities lead to bluer colors in their centers (blue-core galaxies). (ii) By comparing with the SDSS DR7 star-forming galaxy sample, we find that the blue-core galaxies have higher central gas-phase metallicity than what is predicted by the local mass-metallicity relation. We explore the origin of the higher metallicity, finding that not only the blue-core galaxies, but also the flat-gradient and red-core galaxies all have higher metallicity. This can be explained by the combined effect of redshift and galaxy color.
Insight-HXMT observations of the Crab pulsar
Authors: Tuo You-Li , Ge Ming-Yu , Song Li-Ming , Yan Lin-Li , Bu Qing-Cui , Qu Jin-Lu 
Published: June 2019

Abstract
We report on X-ray emission properties of the Crab pulsar (PSR B0531+21) using observations by insight-HXMT during its first year after launch. We obtained high signal-to-noise profiles in the X-ray energy band 11–250 keV. We have confirmed an increase in the flux ratio of the second peak over the main peak with increasing energy, consistent with other missions. The separation of the two peaks shows no significant trend with increasing energy. The phase-averaged spectrum, fitted by a logpar model, and the phase-resolved spectra of the Crab pulsar, fitted by a powerlaw in the different energy bands of HXMT, are consistent with RXTE and NuSTAR in that photon indices evolve as a function of phase as well as a function of energy, contributing to a broadband modeling.
A catalog of DB white dwarfs from the LAMOST DR5 and construction of templates
Authors: Kong Xiao , Luo A-Li , Li Xiang-Ru 
Published: June 2019

Abstract
In this study, we employ machine learning to build a catalog of DB white dwarfs (DBWDs) from the LAMOST Data Release (DR) 5. Using known DBs from SDSS DR14, we selected samples of high-quality DB spectra from the LAMOST database and applied them to train the machine learning process. Following the recognition procedure, we chose 351 DB spectra of 287 objects, 53 of which were new identifications. We then utilized all the DBWD spectra from both SDSS DR14 and LAMOST DR5 to construct DB templates for LAMOST 1D pipeline reductions. Finally, by applying DB parameter models provided by D. Koester and the distance from Gaia DR2, we calculated the effective temperatures, surface gravities and distributions of the 3D locations and velocities of all DBWDs.
Evaluating a proxy of the local entropy production rate on the solar photosphere
Authors: Viavattene G , Berrilli F , Consolini G , Del Moro D , Giannattasio F , Giovannelli L , Penza V 
Published: June 2019

Abstract
The evaluation of the entropy production rate on the solar photosphere and its probability distribution are the key issues for studying the non-equilibrium dynamics of the solar convection. The local entropy production rate can be easily evaluated using the vertical heat flux as a proxy, which is given by a product between the line-of-sight velocity and the surface temperature. In this framework, the solar photosphere provides an incomparable laboratory to study turbulent convection in a dissipative non-equilibrium system near a steady state. In this work, we present some preliminary results on statistics of the local entropy production rate via the vertical heat flux, using line-of-sight velocity and temperature maps of the solar photosphere which are extracted from spectro-polarimetric data making use of the Center of Gravity Method and the simple black body radiation law.
Influence of thermal conductivity and of non-constant relaxation time on thermoelectricity in Mg3Sb2
Authors: Farris R , Maccioni M B , Filippetti A , Fiorentini V 
Published: June 2019

Abstract
We discuss the effects of different approximations to thermal conductivity and relaxation time on the thermoelectric figure of merit ZT in n-doped Mg3Sb2. We use density-functional electronic structure and Bloch-Boltzmann transport theory with an energy-dependent relaxation time. ZT is monotonically increasing with T in our range (300-700 K) with a maximum value of ∼1.5.
The build up of a test station facility for the SIS100 superconducting modules
Authors: Gambardella U , Iannone G , Saggese A 
Published: June 2019

Abstract
More than eighty quadrupole modules, especially designed and fabricated at JNIR in Dubna, will be used at the FAIR facility in Darmstadt. Prior the installation in the new accelerator SIS 100 tunnel, the modules need to be tested by an independent laboratory. The required test have to be the same for all the modules and the answer will be the benchmark for the final decision on accepting or rejecting the module. With this target in mind, a system with as much as possible automatisms will be realized. Three kinds of tests will be performed: mechanical, thermal and electrical. The mechanical test will concern on the search of vacuum leaks, if present, and on the measurement of the limit pressure reached in the vessel. The thermal test will have to check that the various thermometer, scattered inside the modules, will be correctly working and that the heaters are able to deliver the generated heat. The electrical tests will verify the insulation to ground of both the devices and the superconducting coils and bus-bars. All tests will be done in a thermal sequence: at room temperature, at the cryogenic working temperature of 4.5 K, and finally at room temperature again.
Thermal compensation system in advanced and third generation gravitational wave interferometric detectors
Authors: Aiello L , Cesarini E , Fafone V , Lorenzini M , Minenkov Y , Nardecchia I , Rocchi A , Sequino V 
Published: June 2019

Abstract
On September 14
th
2015 the first gravitational wave signal has been detected by the Advanced LIGO interferometers, opening the era of the gravitational astronomy and giving new opportunities to investigate the universe. The Advanced LIGO and Advanced Virgo interferometers are now back in a commissioning phase in order to improve their sensitivity for the next observing run, which will start in the first months of 2019.
In the high-frequencies region of their sensitivity band, the detectors are shot-noise limited: the sensitivity in this frequency window could be improved increasing the laser input power, but this increases also the optical aberrations due to the thermal effects. The optical power absorptions in the substrate and coatings of the optics induce both an increase of the optical path length in the substrates of the mirrors (thermal lensing) and a thermal expansion of the optic itself along the optical axis (thermo-elastic deformation). Both these aberrations reduce the sensitivity of the detector, limiting its performances. In order to face and minimize them, an adaptive Thermal Compensation System is required in order to guarantee the proper operation of the interferometer.
An overview of the present Thermal Compensation System system installed on Advanced Virgo, with also a focus on the possible improvements of the actual actuators for the next generation of detectors, is presented here.