bluuebunny/crossref_metadata_2025_split huggingface dataset:
It’s not just kids that don’t speak English: leaning toward teacher preparation for multilingual learners
Authors: Ankeny Raisa 
Published: December 2024

PurposeThe purpose of this current research study is to provide a comprehensive description of an ongoing effort to provide quality experiential professional development through field experiences for educators at the pre-service level, referred to hereafter as teacher candidates (TCs). This practitioner inquiry aimed to determine what the teacher candidates’ reflections revealed about their learning experiences completing the 10-h checklist.Design/methodology/approachAbout30 individual reports from four consecutive terms were collected. I employed qualitative coding, first using open codes, then grouping similar sentiments into axial codes and through an iterative process categorizing them into themes, grouping and re-generating terms as needed and keeping records in a codebook (Creswell, 2014). The research questions guiding the inquiry included, (1) What do teacher candidates’ reflections reveal about their experience completing the field experience for English Speakers of Other Languages (ESOL) endorsement? And (2) What conclusions do TCs demonstrate about their role as future teachers of multilingual learners (MLLs)?FindingsFindings are summarized under three main recurring themes: emotionality of field experience, perceived misunderstandings and emerging responsiveness to MLLs. Candidates conveyed strong emotional responses to the instructional context. Some were forward in acknowledging stereotypes and trepidation to participate in the experience. Others reflected on their understanding of the experience, their interpretations of teacher relationships and noted attitude shifts toward MLLs. Findings reported emergent responsiveness to MLLs imply that candidates in this beginning experience progressed at various rates, suggesting that assessing competence of skills at the onset may be beneficial for further understanding best approaches to teacher education.Originality/valueThere is certainly a gap in current knowledge when it comes to understanding the rates at which teacher candidates develop abilities, skills and orientations toward working with MLLs. These preliminary findings support established notions such as the importance of exposing students to authentic environments that foster appreciation for the complexities of the process of second language acquisition and acculturation. Findings reported around emergent responsiveness to MLLs imply that candidates in this beginning experience progressed at various rates, suggesting that assessing competence of skills at the onset may be beneficial for further understanding best approaches to teacher education.
Out-of-school children and the role of social reconstructionism in education in the context of Cambodia: an implication for reform policy
Authors: Bunthorn Yem 
Published: December 2024

Purpose
This study aims to explore the factors contributing to the out-of-school children (OOSC) issue at the primary level in Cambodia and related initiatives in addressing the challenges, drawing upon the application of social reconstructionism in addressing the issue.

Design/methodology/approach
This paper reviews and analyzes relevant, existing literature, including scholarly articles, reports, policy documents and books.

Findings
Despite efforts by the government, Ministry of Education, Youth and Sport and non-government organizations, the issue of OOSC remains a challenge. Integration of social reconstructionist principles offers a transformative approach to address the OOSC issue, as well as systemic educational disparities.

Research limitations/implications
This review paper lacks empirical findings of its own and relies solely on the availability and quality of the relevant sources, setting direction for future research to explore empirical findings.

Practical implications
The findings underscore the importance of adopting a holistic and socially conscious approach to education, incorporating social reconstructionist principles in reform policy.

Social implications
Addressing the OOSC in Cambodia is crucial for promoting social equity and breaking the cycle of poverty, highlighting the need for inclusive education policies.

Originality/value
This study contributes to the existing literature and builds upon it to offer a novel perspective of applying social reconstructionist principles in reform policy to address the OOSC issue, as well as the potential of a transformative approach to dealing with systematic educational disparities.
A survey of academic library public service policies, training and assessment practices
Authors: Knoff Meredith , Press Meggan 
Published: December 2024

PurposeThis study seeks to better understand if academic libraries are generating service policies broadly and if they differentiate between a customer service focus and research assistance perspective. It also examines the level of training and assessment conducted to maintain and update service policies.Design/methodology/approachResearchers developed an online survey collecting data on demographic, policy development, training and assessment practices.FindingsOnly a very small number of respondents reported having any kind of policy, regardless if it was a customer service or reference/research policy. Within the small number of libraries that reported having any sort of policy, an even smaller number perform any type of assessment on these policies. Furthermore, between the 2021 and 2023 deployments of the surveys, there was an obvious decrease in many areas surveyed.Originality/valueThe implications of this study can inform the development, implementation and assessment of library service policies at academic libraries.
Commentary on “An interdisciplinary approach to improve oral motor fluency and speech production: a case study”
Authors: Mapp Tracy 
Published: December 2024

Purpose
The purpose of this paper is to explore the process applied by Schepp et al. (2024; this issue) to enhance the acquisition of speech production. It discusses its relevance to individuals with intellectual and developmental disabilities (IDD), with a particular focus on motor movements and leisure skills. The intention is to encourage practitioners to consider the scope of application possibilities and to connect further with the literature surrounding fluency of motor movements and precision teaching.

Design/methodology/approach
A narrative approach is applied throughout. Context of skill proficiency, performance and practices for completing component-composite analyses are described, with a practical example given. Variable and critical features of precision teaching relative to discussed aspects are emphasised.

Findings
Fluency in fundamental movements is foundational for developing more complex skills. A component-composite analysis is a helpful, structured approach for identifying precursor skills. These approaches are particularly beneficial for individuals with IDD, who often experience motor movement challenges and barriers in accessing leisure activities.

Originality/value
This paper adds to existing descriptions and discussions regarding the purpose and practical process of identifying precursor skills, then fluency building to performance criterion. Less commonly discussed is the relationship between these and critical and variable features of precision teaching, which are highlighted here. Attention is also drawn to the lesser reported scope of applying these practices to leisure-orientated goals for individuals with IDD.
Creating a food environment scoring index for online food delivery outlets: Delphi study with Australian nutrition and public health professionals
Authors: Bennett Rebecca , Zorbas Christina , Alston Laura , Needham Cindy 
Published: December 2024

AbstractAimsThis study aimed to develop a scoring index for the healthfulness of food outlet menu offerings available through Australian delivery platforms.MethodsThe Delphi method was employed to achieve consensus among a panel of Australian nutrition and public health experts regarding the food environment scores assigned to online food outlets, classified by type. From previous studies and scoping of delivery platforms, 36 food outlet types were identified. Australian nutrition and public health experts were recruited to complete an online Delphi survey to score the healthfulness of these outlets using a scale from −10 (least healthful) to +10 (most healthful), based on typical menu offerings. The first round of the survey was opened for approximately 5 weeks in July to August 2023, and the second round was opened for 2 weeks in September 2023. The mean food environment score, minimum and maximum awarded food environment score, and SD for each outlet type, and coefficient of variation was calculated after each survey round to provide a measure of the spread of the data around the mean and the degree of consistency in the distribution of responses. Following the second survey round, results were assessed for consensus among the participants.ResultsFifty‐four participants completed the round one survey, and n=14 completed round two. The majority of online food delivery outlet types received a food environment score of less than +5, and were considered ‘less healthful.’ Participants scored greengrocers as the most healthful outlet type (mean food environment score of 8.83 ± 0.37) and liquor selling stores as the least healthful (score of −8.10 ± 1.14). The group reached consensus after two survey rounds due to decreases in the standard deviations of mean food environment scores.ConclusionsThis study provides an expert‐informed tool, the DIGIASSESS tool, that can be easily applied by researchers, policy makers, health workers and public health professionals to understand the rapidly evolving online food delivery environment, including changes over time and areas for potential intervention.
‘Keeps me young at heart’: Exploring the influence of volunteering on social connection, health and well‐being in rural Australia
Authors: Williams Tara , Lakhani Ali , Spelten Evelien 
Published: December 2024

AbstractObjectiveThe negative consequences of social disconnection, including loneliness and social isolation, is receiving considerable attention from researchers and policymakers, and growing as a global public health priority. Volunteering has emerged as a promising strategy to promote social connection and combat loneliness, calling for a closer examination of its potential benefits to individual social health and community cohesion. This study explores the experiences and impact of volunteering on individuals' social health, providing insights into both the positive impacts and possible limitations of volunteering in rural communities.Design/Setting/ParticipantsTwenty‐two volunteers (6 males; 16 females) in one rural Northern Victoria community participated in semi‐structured interviews via telephone, online or face‐to‐face. Thematic analysis was used to develop descriptive themes from the qualitative data.ResultsFour themes were identified: (1) creating social and community bonds, (2) giving back to the community, (3) building identity through volunteering and (4) social identity and belonging. Findings suggest that volunteering helps individuals to meet new people, increase opportunities for social interactions with others and within social groups, positively influencing their social identity and the identity of the community. Volunteers, who felt connected through their volunteering, experienced a sense of belonging. However, when feeling overburdened or undervalued, volunteers disengaged and sought new volunteering opportunities.ConclusionsThis study demonstrates the influence of rural volunteering on volunteer's social connections, identity and social health. Creating flexible, accessible and inclusive volunteering opportunities acts as a valuable community resource for building and maintaining social health and connection and reduces social disconnection in rural populations.
Outcomes of pancreatectomy for histologically proven intraductal papillary mucinous neoplasm with reference to Fukuoka guidelines
Authors: Lee Kit Fai , Lo Eugene Y. J. , Lok Hon Ting , Fung Andrew K. Y. , Kung Janet K. C. , Chong Charing C. N. , Wong John , Lai Paul B. S. 
Published: December 2024

AbstractBackgroundIntraductal papillary mucinous tumour (IPMN) of pancreas is increasingly recognized to have malignant potential. Fukuoka guidelines are commonly used to select patients with IPMN for resection due to high chance of malignancy, which includes high‐grade dysplasia (HGD) or invasive carcinoma (IC).MethodsA retrospective study on consecutive patients who have undergone pancreatectomy with IPMN as the final pathology was performed. Operative and survival outcomes were analysed. The positive predictive values (PPV) of high‐risk stigmata (HRS) and worrisome features (WF) of Fukuoka guidelines for HGD/IC were determined.ResultsBetween August 2011 and September 2020, various types of pancreatectomy were performed for 36 patients with histologically proven IPMN. They included 26 pancreaticoduodenectomy, 7 distal pancreatectomy, 2 central pancreatectomy, and 1 total pancreatectomy. There were 30 branch duct type IPMN, 5 main duct type, and 1 mixed type. There was no 30‐day mortality. Overall complications and pancreatic fistula occurred in 44.4% and 5.6% of patients, respectively. Patients without HGD/IC had 100% survival at 5 years with no recurrent disease. There were 13 patients with HGD/IC, their 1‐, 3‐, 5‐year overall and disease‐free survival were 84.6%, 76.9%, 67.3% and 84.6%, 68.4%, 58.6%, respectively, both significantly shorter than non‐HGD/IC group (P = 0.002 and 0.001, respectively). The PPV of HRS and WF for HGD/IC were 33.3% and 23.5%, respectively. The combined PPV of HRS and WF for HGD/IC was 38.0%.ConclusionSurvival after pancreatectomy for IPMN was favourable, but was significantly worse in the presence of HGD/IC. Fukuoka guidelines were useful in predicting malignant IPMN.
Mass‐forming intrahepatic cholangiocarcinoma: treatment outcomes after curative‐intent resection in an Australian tertiary referral hospital
Authors: Martens Sander R. W. J. , Bhimani Nazim , Gofton Cameron , Brown Kai M. , de Reuver Philip R. , Hugh Thomas J. 
Published: December 2024

AbstractBackgroundMass‐forming intrahepatic cholangiocarcinoma (MF‐ICC) is the second most common primary liver cancer and liver resection offers the best chance of possible cure. This study aimed to assess treatment outcomes and prognostic factors for long‐term survival in patients who underwent curative‐intent liver resection.MethodsA retrospective analysis was conducted on prospectively collected data from patients with MF‐ICC managed at the Royal North Shore/North Shore Private Hospital from January 1998 to October 2023. Baseline, peri‐operative and long‐term outcomes have been analysed, including an overall survival (OS) and disease‐free survival (DFS) analysis.ResultsDuring the 25‐year study period, 47 patients underwent curative‐intent liver resection for primary MF‐ICC at a median age of 70 years. The median OS was 36 months, with a 5‐year OS of 33%. Multiple liver tumours (HR = 2.84; 95% CI = 1.24–6.48; P = 0.013) and a positive resection margin (HR = 2.46; 95% CI = 1.10–5.52; P = 0.029) were identified as independent predictors of poor long‐term OS. Recurrence occurred in 62% of patients after a median DFS of 16 months, with poor tumour differentiation (HR = 3.93; 95% CI = 1.62–9.54; P = 0.002) and elevated tumour markers (HR = 3.47; 95% CI = 1.53–7.87; P = 0.003) as independent predictors of poor DFS.ConclusionLiver resection can offer a significant chance for prolonged survival in a highly selected population of patients with MF‐ICC. However, the surgical challenges inherent in treating this rare disease are evident, emphasizing the need for a multimodal approach and continued exploration of additional therapies to enhance personalized treatment strategies.
Biallelic Variants in LRRC45 Impair Ciliogenesis and Cause a Severe Neurological Disorder
Authors: Radhakrishnan Periyasamy , Quadri Neha , Erger Florian , Fuhrmann Nico , Geist Otilia‐Maria , Netzer Christian , Khyriem Ibakordor , Muranjan Mamta , Udani Vrajesh , Yeole Mayuri , Mascarenhas Selinda , Limaye Sanket , Siddiqui Shahyan , Upadhyai Priyanka , Shukla Anju 
Published: December 2024

ABSTRACTLeucine ‐ rich repeat containing 45 protein (LRRC45) protein localizes at the proximal end of centrioles and forms a component of the proteinaceous linker between them, with an important role in centrosome cohesion. In addition, a pool of it localizes at the distal appendages of the modified parent centriole that forms the primary cilium and it has essential functions in the establishment of the transition zone and axonemal extension during early ciliogenesis. Here, we describe three individuals from two unrelated families with severe central nervous system anomalies. Exome sequencing identified biallelic variants in LRRC45 in the affected individuals: P1: c.1402‐2A>G; P2 and P3: c.1262G>C (p.Arg421Thr). Investigation of the variant c.1402‐2A>G in patient‐derived skin fibroblasts revealed that it triggers aberrant splicing, leading to an abnormal LRRC45 transcript that lacks exon 14. Consistent with this the mRNA and protein levels of LRRC45 were drastically reduced in P1‐derived fibroblast cells compared to the controls. P1 fibroblasts showed a significant reduction of primary cilia frequency and length. In silico modeling of the missense variant in P2/P3 suggested a destabilizing effect on LRRC45. Given these findings, we propose that the pathogenic loss‐of‐function variants in LRRC45 are associated with a novel spectrum of neurological ciliopathy phenotypes.
Impaired Basal Forebrain Cholinergic Neuron GDNF Signaling Contributes to Perioperative Sleep Deprivation–Induced Chronicity of Postsurgical Pain in Mice Through Regulating Cholinergic Neuronal Activity, Apoptosis, and Autophagy
Authors: Wang Dong , Wei Shi‐Nan , Zhang Lu , Lang Zhi‐Chen , Wang Si‐Nian , Cheng Bo , Lu Yan , Wang Xiu , Wang Wei , Li Feng‐Sheng , Zhang Hao 
Published: December 2024

ABSTRACTAimsThis study investigated the roles of lateral basal forebrain glial cell line–derived neurotrophic factor (GDNF) signaling and cholinergic neuron activity, apoptosis, and autophagy dysfunction in sleep deprivation–induced increased risk of chronic postsurgical pain (CPSP) in mice.MethodsSleep deprivation (6 h per day from −1 to 3 days postoperatively) was administered to mice receiving skin/muscle incision and retraction (SMIR) to determine whether perioperative sleep deprivation induces mechanical and thermal pain hypersensitivity, increases the risk of chronic pain, and causes changes of basal forebrain neurons activity (c‐Fos immunostaining), apoptosis (cleaved Caspase‐3 expression), autophagy (LC3 and p62 expression) and GDNF expression. Adeno‐associated virus (AAV)‐GDNF was microinjected into the basal forebrain to see whether increased GDNF expression could reverse sleep deprivation–induced changes in pain duration and cholinergic neuron apoptosis and autophagy. Cholinergic neurons were further depleted by mu p75‐SAP to examine whether the pain‐prolonging effects of sleep deprivation still exist.ResultsPerioperative sleep deprivation enhanced pain sensation and prolonged pain duration in SMIR mice, which was accompanied by decreased cholinergic neuron activity and GDNF expression, increased apoptosis, and autophagy dysfunction in the substantia innominata (SI), magnocellular preoptic nucleus (MCPO), and horizontal diagonal band Broca (HDB) (hereafter lateral basal forebrain). Normalizing cholinergic neuron GDNF expression by AAV‐GDNF in the lateral basal forebrain inhibited apoptosis and autophagy dysfunction and mitigated sleep deprivation–induced pain maintenance. Mice with selective lesion of lateral basal forebrain cholinergic neurons were resistant to the pain‐enhancing and prolonging effects of sleep deprivation and the pain‐alleviating effects of AAV‐GDNF therapy.ConclusionsPerioperative sleep deprivation promotes chronicity of postsurgical pain possibly through decreasing basal forebrain GDNF signaling and causing cholinergic neuronal apoptosis and autophagy dysfunction.
Ginsenoside Rg1: A Neuroprotective Natural Dammarane‐Type Triterpenoid Saponin With Anti‐Depressive Properties
Authors: Han Dong , Zhao Zheng , Mao Tinghui , Gao Man , Yang Xue , Gao Yan 
Published: December 2024

ABSTRACTBackgroundDepression, a widespread mental disorder, presents significant risks to both physical and mental health due to its high rates of recurrence and suicide. Currently, single‐target antidepressants typically alleviate depressive symptoms or delay the progression of depression rather than cure it. Ginsenoside Rg1 is one of the main ginsenosides found in Panax ginseng roots. It improves depressive symptoms through various mechanisms, suggesting its potential as a treatment for depression.Materials and MethodsWe evaluated preclinical studies to comprehensively discuss the antidepressant mechanism of ginsenoside Rg1 and review its toxicity and medicinal value. Additionally, pharmacological network and molecular docking analyses were performed to further validate the antidepressant effects of ginsenoside Rg1.ResultsThe antidepressant mechanism of ginsenoside Rg1 may involve various pharmacological mechanisms and pathways, such as inhibiting neuroinflammation and over‐activation of microglia, preserving nerve synapse structure, promoting neurogenesis, regulating monoamine neurotransmitter levels, inhibiting hyperfunction of the hypothalamic‐pituitary‐adrenal axis, and combatting antioxidative stress. Moreover, ginsenoside Rg1 preserves astrocyte gap junction function by regulating connexin43 protein biosynthesis and degradation, contributing to its antidepressant effect. Pharmacological network and molecular docking studies identified five targets (AKT1, STAT3, EGFR, PPARG, and HSP90AA1) as potential molecular regulatory sites of ginsenoside Rg1.ConclusionsGinsenoside Rg1 may exert its antidepressant effects via various pharmacological mechanisms. In addition, multicenter clinical case‐control and molecular targeted studies are required to confirm both the clinical efficacy of ginsenoside Rg1 and its potential direct targets.
The Prevalence of Diffuse Large B‐Cell Lymphoma Varies Substantially by Methods Applied: Results From a Population‐Based Study
Authors: Simonsen Mikkel Runason , Jensen Jonas Faartoft , Larsen Thomas Stauffer , Gade Inger‐Lise , de Nully Brown Peter , El‐Galaly Tarec Christoffer 
Published: December 2024

ABSTRACTObjectivesAccurate prevalence estimates of diffuse large B‐cell lymphoma (DLBCL) are important for numerous purposes including orphan drug designation. A key criterion for orphan drug designation is a disease prevalence of less than 5/10,000 persons. The objective is to apply and compare different methods of prevalence assessment.MethodsIn the present nationwide Danish cohort study, the prevalence of DLBCL was assessed using different methodologies, including register‐based and formula‐based approaches.ResultsThe prevalence calculations were based on 9,492 patients diagnosed with DLBCL since year 2000. Incidence increased and survival improved in the period, resulting in higher prevalence of DLBCL. In year 2023, the 2‐,3‐,5‐,10‐, and 20‐year prevalences were 1.53, 2.19, 3.45, 6.08, and 8.80 per 10,000 adults using the register‐based approach. The formula‐based approach was generally accurate when using restricted mean survival. However, when using median survival, the total prevalence was estimated at 8.1 per 10,000 adults. Furthermore, when extrapolating the median survival from the 5‐year survival under constant hazard assumption as done in some orphan drug designation reports, the prevalence was estimated at 6.6 per 10,000 adults.ConclusionsIn conclusion, the estimated DLBCL prevalences are sensitive to the applied method. DLBCL would disqualify from orphan drug designation in some of the mentioned scenarios.