bluuebunny/crossref_metadata_2025_split huggingface dataset:
Key factors to consider forCandida aurisscreening in healthcare settings: a systematic review
Authors: Danielsen Anders Skyrud , Ødeskaug Liz Ertzeid , Raastad Ragnhild , Kjerulf Anne , Andersen Anne-Marie , Tornes Ragnhild Agathe , Himmels Jan P. W. , Dahle Ulf R. , Sare Miriam , Kristensen Brian , Eriksen-Volle Hanne-Merete , Molvik Mari 
Published: November 2024

AbstractBackgroundCandida aurisis an emerging fungal pathogen that is often multidrug-resistant. It can persist on skin and in hospital environments, leading to outbreaks and severe infections for patients at risk. Several countries and institutions are working on establishing guidelines and recommendations for prevention. This review aims to assess the evidence on factors associated withC. auriscolonisation or infection, the duration of such colonisation, possible colonisation sites, and the risk of secondary cases to inform screening recommendations.MethodsWe systematically searched five databases for primary studies and systematic reviews of our four outcomes. We excluded studies on treatment, management, laboratory methods, drug resistance, and environmental screening. From each paper, we extracted relevant data and summarised them in tables. Main findings were described narratively.FindingsWe selected 117 studies for inclusion. Most of the studies were observational studies. Without taking the method of testing into account, the duration ofC. auriscolonisation varied, with up to and beyond a year being common. The predominant sites of colonisation were the axillae and groin, with the nares and rectum being less common sites. The risk of secondary cases saw considerable variation across the studies, and the secondary cases primarily involved patients and not health care workers. Critical care settings, invasive medical devices, recent antimicrobial use, and comorbidities were often associated withC. auriscolonisation and infection.ConclusionOur review highlights that, despite relevant findings on factors influencingC. auriscolonisation and infection, substantial gaps remain in the evidence supporting screening practices. Most studies were conducted reactively, in outbreak settings, and lack systematic protocols. Given these limitations, screening guidelines are likely to be more successful if grounded in medical theory and yeast microbiology rather than relying solely on current studies. Rigorous, well- designed research is urgently needed to inform futureC. aurisscreening and control efforts.
Opioid Overdose and Naloxone Administration Knowledge and Perceived Competency in A Probability Sample of Indiana Urban Communities with Large Black Populations
Authors: Lee Shin Hyung , Agley Jon , Sharma Vatsla , Williamson Francesca , Zhang Pengyue , Seo Dong-Chul 
Published: November 2024

AbstractBackgroundDespite widespread naloxone distribution efforts, opioid-involved overdose rates remain high, with rates in recent years indicating disproportionate increases in the death rate for Black residents. This study evaluated knowledge and perceived competency regarding opioid overdose and naloxone administration among urban Indiana residents.MethodsAs part of a federally funded project (#CPIMP221346), the Indiana University Center for Survey Research conducted community probability surveys from March to May 2023, sampling 772 residents in Indiana’s urban communities across 8 zip code areas. The study explored individual and community level factors affecting residents’ knowledge and perceived competency regarding opioid overdose and naloxone administration.ResultsMultilevel analysis identified race, sex, household income, education, length of time lived in community, and a history of opioid overdose as significant predictors of knowledge. Participants who identified as White scored a mean of 6.65 out of 10, those of Other races scored 5.75, and Black participants scored 5.70, on a 10 item questionnaire developed from the Overdose Knowledge Scale (OOKS) and the Opioid Overdose Attitudes Scale (OOAS) (p< 0.001). Additionally, there was significant cross-level interaction between race and poverty, such that Black residents living in poorer neighborhoods displayed lower knowledge scores than White counterparts (□ = 1.06,p= 0.039). However, in terms of perceived competency, only age and a history of opioid overdose, were found to be significant predictors.ConclusionsThese findings underscore the importance of community education to increase knowledge and perceived competency regarding opioid overdose and naloxone administration among Black populations particularly living in socioeconomically disadvantated areas.
Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression
Authors: Shannon Nathaniel , Raymond Cory , Palmer Chloe , Seward David , Cunniff Brian 
Published: November 2024

AbstractSubcellular mitochondrial positioning in cells is necessary for localized energy and signaling requirements. Mitochondria are strategically trafficked throughout the cytoplasm via the actin cytoskeleton, microtubule motor proteins, and adaptor proteins. Miro1, an outer mitochondrial membrane adaptor protein, is necessary for attachment of mitochondria to microtubule motor proteins for trafficking. Previous work showed when Miro1 is deleted (Miro1-/-) from mouse embryonic fibroblasts (MEFs), the mitochondria become sequestered to the perinuclear space, disrupting subcellular energy and reactive oxygen species gradients. Here, we show that Miro1-/-MEFs grow slower compared to Miro1+/+and Miro1-/-MEFs stably re-expressing the Myc-Miro1 plasmid. Miro1-/-MEFs have a have a cell cycle defect with decreased percentage of cells in G1 and increased cells in the S phase of the cell cycle. We conducted the first ever RNA sequencing experiment dependent upon Miro1 expression and found differential expression in cell proliferation and migration genes upon deletion of Miro1, including the MAP Kinase signaling pathway. We find that ERK1/2 phosphorylation is elevated both spatially (cytoplasm and nucleus) and temporally following serum stimulation in Miro1-/-MEFs. We investigated the expression levels and oxidation of the Dual Specificity Phosphatases (DUSP1-6), ERK1/2 target phosphatases. We found no differences in DUSP1-6 expression and oxidation under asynchronous and synchronized cells. Lastly, we evaluated the oxidation status of ERK1/2 and found an increase in ERK1/2 oxidation in the Miro1-/-MEFs compared to Miro1+/+and Myc-Miro1. These data highlight transcriptional control based off Miro1 expression and demonstrate the highly dynamic regulation of ERK1/2 upon deletion of Miro1 that may support the observed cell cycle and proliferation defects.
Relationship between orbital moment anisotropy, magnetocrystalline anisotropy, and Dzyaloshinskii-Moriya interaction in W/Co/Pt trilayers
Authors: Chi Zhendong , Lau Yong-Chang , Zhang Vanessa Li , Shibata Goro , Sakamoto Shoya , Nonaka Yosuke , Ikeda Keisuke , Wan Yuxuan , Suzuki Masahiro , Kawaguchi Masashi , Suzuki-Sakamaki Masako , Amemiya Kenta , Kawamura Naomi , Mizumaki Masaichiro , Suzuki Motohiro , Yang Hyunsoo , Hayashi Masamitsu , Fujimori Atsushi 
Published: November 2024

We have studied the Co layer thickness dependences of magnetocrystalline anisotropy (MCA), Dzyaloshinskii-Moriya interaction (DMI), and orbital moment anisotropy (OMA) in W/Co/Pt trilayers, in order to clarify their correlations with each other. We find that the MCA favors magnetization along the film normal and monotonically increases with decreasing effective magnetic layer thickness (teff). The magnitude of the Dzyaloshinskii-Moriya exchange constant (|D|) increases with decreasing teff until teff∼1 nm, below which |D| decreases. The MCA and |D| scale with 1/teff for teff larger than ∼1 nm, indicating an interfacial origin. The increase of MCA with decreasing teff continues below teff∼ 1 nm, but with a slower rate. To clarify the cause of the teff dependences of MCA and DMI, the OMA of Co in W/Co/Pt trilayers is studied using x-ray magnetic circular dichroism. We find nonzero OMA when teff is smaller than ∼0.8 nm. The OMA increases with decreasing teff more rapidly than what is expected from the MCA, indicating that factors other than OMA contribute to the MCA at small teff. The teff dependence of the OMA also suggests that |D| at teff smaller than ∼1 nm is not related to the OMA at the interface. We propose that the growth of Co on W results in a strain and/or texture that reduces the interfacial DMI, and, to some extent, MCA at small teff.

Published by the American Physical Society
2024
A cross-generational analysis of second-hand online shopping: comparing GenX, millennials and GenZ
Authors: Calvo-Porral Cristina , Viejo-Fernández Nuria 
Published: November 2024

Purpose
The purpose of this study is to examine whether there are differences in second-hand online shopping behavior driven by the generational cohort.

Design/methodology/approach
Based on the generational cohort theory, this research examines what factors influence and prevent the purchase of second-hand products online, comparing generational cohorts. For this purpose, data are analyzed through multiple-group structural equation modeling (SEM) (Gen X = 176; Millennials = 197; Gen Z = 233).

Findings
Findings report noticeable different motivations and barriers across consumer generations in their second-hand shopping behavior: Gen X are mostly driven by economic motivations; Gen Z are driven by ethical motives, while economic and environmental motivations exert greater influence for Millennials. Conversely, functional risk is the main barrier for the three generational cohorts.

Originality/value
To the best of the authors’ knowledge, this is one first attempt to examine why different generational cohorts of consumers purchase or prevent from purchasing used items through the internet.
The ethics of facial recognition in police practice: beyond the usual concerns
Authors: Miah Abdul-Hye , Mcbride Neil 
Published: November 2024

Purpose
This paper aims to outline an ethical framework for the deployment of facial recognition technology (FRT) in policing practice and highlight the ethical significance of the facial image.

Design/methodology/approach
This paper sets out an ethical approach to the practice of facial recognition deployment derived from Emmanuel Levinas’ Ethics of the Face. Ideas concerning alterity and the role of the face as a source of ethical obligation are used to establish the significance of responsibility and accountability in FRT usage.

Findings
Reflecting on the ethics of the face suggests that facial recognition amplifies requirements for accountability and responsibility in comparison with other biometric techniques and requires stronger legal safeguards.

Practical implications
This paper offers practical improvements through: improved process in applying FRT and changes to information management practice which treat the facial image with heightened accountability and traceability. Training is suggested which creates an understanding of the face and an improved approach to the information management of FRT data. Recommendations are made on selection of officers deployed in the field.

Originality/value
Using Levinas’ concept of the face and ethical philosophy provides a unique and novel lens for characterizing the legal and ethical issues concerning FRT in police practice and results in new insights as to the productive use of FRT in public policing.
Bystanders’ support for online customer complaints: an integrated perspective of deontic justice theory and attribution theory
Authors: Zhang Jin , Weng Zhigang 
Published: November 2024

Purpose
Online complaints have emerged as a pivotal avenue for customers to voice their dissatisfaction. In this context, bystanders, as third-party observers, actively engage in evaluating and judging these complaints. However, studies pertaining to bystanders in online customer complaints remain limited. Therefore, this study aims to integrate deontic justice theory and attribution theory to construct a research model of bystanders’ support for online customer complaints.

Design/methodology/approach
Leveraging a questionnaire and two scenario experiments, SPSS 24.0 and AMOS 24.0 were used to examine the relationship between bystanders’ moral outrage and their support for online customer complaints, the mediating role of responsibility attribution and the moderating role of experience similarity and online anonymity.

Findings
Based on the statistical analysis, the results show that bystanders’ moral outrage significantly enhances their support for online customer complaints; responsibility attribution plays a mediating role between moral outrage and bystanders’ support for online customer complaints; experience similarity and online anonymity can moderate the relationship between moral outrage and bystanders’ support for online customer complaints.

Originality/value
The findings of this study not only enrich the literature on online customer complaints but also provide valuable insights for companies to understand the diffusion of online complaints and effective strategies with which to address them.
Construction and validation of the cognitive attitudes toward inclusive education scale among teachers and paraprofessionals in the French context
Authors: Legrain C. , Brasselet C. , Khamzina K. , Jury M. , Desombre C. 
Published: November 2024

AbstractRecent years have seen a growing shift toward global inclusive policies. Previous research highlighted the development of inclusive education, which notably requires collaboration among multiple actors (i.e., teachers, paraprofessionals, families). Among the barriers and levers to this implementation, attitudes toward inclusive education have been the subject of particular scholarly inquiry. This article reports two studies conducted to develop a French‐speaking scale to address the emerging challenges in inclusive education by virtue of its suitability for a variety of actors. The 12 items of the Cognitive Attitudes Toward Inclusive Education Scale (CATIES) were derived from nine pre‐existing scales. Two studies (N = 180 and N = 228) involving teachers and paraprofessionals (e.g. psychologists, special educators, nurses, and other paraprofessionals working in medical‐educational facilities) were conducted within the French context to establish the scale's psychometric properties, such as internal consistency and convergent validity. Results reveal a reliable and valid tool with a three‐dimensional structure measuring teachers' attitudes toward teaching students with special educational needs, benefits and risks of inclusive education on students with and without special educational needs and classroom management. In light of its relevance to a variety of inclusion stakeholders, this scale offers perspectives for more reliable inclusive education research.
Tryptophan‐immunoadsorption plasmapheresis regulates polymorphonuclear‐myeloid‐derived suppressor cells and pro‐inflammatory cytokines
Authors: Wakabayashi Hanae , Hattori Noriyuki , Uzawa Akiyuki , Ito Michihiro , Hasegawa Hiroko , Mimura Naoya , Empitu Maulana , Aizawa Masashi , Kuwabara Satoshi , Asanuma Katsuhiko , Oda Shigeto 
Published: November 2024

AbstractIntroductionImmunoadsorption plasmapheresis (IA) has been reported to have immunoregulatory effects, in addition to the removal of autoantibodies. This study aimed to investigate the effects of IA on the proportion of myeloid‐derived suppressor cells (MDSCs) that potentially suppress autoimmune responses and regulate immunity.MethodsThe study included 21 patients with autoimmune neurological diseases and 8 healthy participants. We measured polymorphonuclear (PMN)‐MDSCs (CD14−CD11b+CD33+) and inflammation‐related mediators before and after a single session of tryptophan‐IA. We also investigated whether an increase in PMN‐MDSCs after initial IA was a predictor of clinical efficacy in nine patients with myasthenia gravis based on the Quantitative Myasthenia Gravis score.ResultsFor a total of 36 times of IA procedures, the number of PMN‐MDSCs significantly increased after IA. Interleukin‐10, monocyte chemoattractant protein‐1 and macrophage inflammatory protein‐1β levels showed significant increases after IA. Despite similar severity at admission, the Quantitative Myasthenia Gravis scores at discharge were significantly lower in the group in which IA increased PMN‐MDSCs to a level of 20% of peripheral blood mononuclear cells or more.ConclusionTryptophan‐IA regulates PMN‐MDSCs and pro‐inflammatory cytokines, possibly leading to suppression of autoimmune responses and tissue damage in neuroimmunological disorders.
Viscoelastic testing of fibrinolytic capacity in acutely infected critically ill patients: Protocol for a scoping review
Authors: Self Matthew , Coupland Lucy , Aneman Anders 
Published: November 2024

AbstractIntroductionViscoelastic testing (VET) has been implemented in clinical care to diagnose and manage coagulation in patients with manifest or high risk of major bleeding. However, the breakdown of formed blood clots, that is, fibrinolysis, has been comparatively less studied. There is an increasing recognition that acute infections trigger a dysregulated immunothrombotic response, which has focused attention on viscoelastic testing to identify in particular fibrinolysis resistant states.MethodsThis scoping review on fibrinolysis assessment using viscoelastic testing will be conducted according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses extension for Scoping Reviews (PRISMA‐ScR). Publications will be included in the review if they evaluate the fibrinolytic capacity of adult patients admitted to an intensive care unit (ICU) for acute infection (including SARS‐CoV2) using VET assays that included a fibrinolytic agent. No date or language restrictions will be applied, and all study designs will be considered. A peer‐reviewed search strategy will be employed in multiple electronic bibliographic databases and will also include the grey literature.ResultsThe included studies will be reported by descriptive analyses and tabulated results.ConclusionThis scoping review aims to map the research describing viscoelastic testing (VET) to assess fibrinolysis in acutely infected critically ill patients, with the goal of identifying diagnostic capabilities, any associations with patient outcomes, and the potential to guide clinical management.
Epidural analgesia versus systemic opioids for postoperative pain management after VATS: Protocol for a systematic review
Authors: Holm Jimmy H. , Bak Mikkel , Brøchner Anne C. 
Published: November 2024

AbstractBackgroundPostoperative pain following video‐assisted thoracoscopic surgery (VATS) remains a significant challenge. While epidural analgesia is still the gold standard, other types of regional analgesia are gaining popularity because of perceived less risk of complications. The efficacy of systemic opioids as an alternative to epidural analgesia has not been thoroughly explored. This systematic review and meta‐analysis aims to evaluate and compare the efficacy of systemic opioids versus epidural analgesia in managing postoperative pain after VATS.MethodsWe will conduct a systematic review and meta‐analysis in accordance with the Cochrane Handbook and the Preferred Reporting Items for Systematic review and Meta‐Analysis Protocols (PRISMA‐P) checklist. A comprehensive search will be conducted in MEDLINE, EMBASE, and the Cochrane Library supplemented with Scopus citation searches, search for gray literature using Google Scholar and a search for ongoing studies. We will include studies based on the PICO methodology without restrictions regarding study type. Two independent reviewers will screen studies, extract data, and assess study quality using the Cochrane Risk of Bias tools. The primary outcomes will be postoperative pain intensity at rest and during activity at 24, 48, and 72 h. Secondary outcomes will include use of “rescue” opioids, hospital length of stay, and adverse events. If feasible, a meta‐analysis will be done, otherwise we will perform a descriptive analysis.ResultsThe results will provide a comparative analysis of the effectiveness of systemic opioids versus epidural analgesia in managing postoperative pain in VATS patients. Data synthesis will include pooled estimates for pain scores, opioid consumption, and adverse events, possibly with subgroup and sensitivity analyses conducted to explore heterogeneity across studies.ConclusionsThis systematic review will offer valuable insights into the optimal pain management strategy for patients undergoing VATS. The findings may guide clinical practice in selecting the most effective and safe analgesic approach, improving postoperative recovery, and patient outcomes.
The recursive impact in the multivariate probit model: An application on farmers’ decisions for opting risk management strategies
Authors: Shah Jamal , Alharthi Majed 
Published: November 2024

AbstractThis study investigates the determinants of farmers’ risk management decisions in Khyber‐Pakhtunkhwa, Pakistan, using a recursive multivariate probit (RMVP) model. Employing data from 382 farmers collected through a multistage sampling process, the study compares the RMVP with the traditional multivariate probit (MVP) model, demonstrating the superior performance of the RMVP in capturing complex decision‐making patterns. Our rigorous statistical analysis demonstrates the significant impact of endogenous covariates on farmers’ risk management choices, revealing complementarity or substitutability among strategies. The study contributes to the literature by providing empirical evidence on the effectiveness of the RMVP model for understanding smallholder farmers’ risk management behavior and offering insights for policymakers to support resilient agricultural systems.
Graft detachment rates in surgeon‐cut and pre‐cut tissue for DSAEK transported in different mediums
Authors: Olafsdottir Thorbjörg , Hootak Faisal , Forslund Carina , Olafsdottir Eydis , Gustafsson Ingemar 
Published: November 2024

AbstractPurposeTo analyse graft detachment rates after Descemet stripping automated endothelial keratoplasty (DSAEK) using surgeon‐cut grafts and pre‐cut grafts transported in different mediums.MethodsA retrospective study of graft detachment rates including 265 surgeries (240 patients) performed between 2019 and 2023. The DSAEK grafts were either surgeon‐cut (n = 135) or pre‐cut and transported in a dextran‐containing medium (n = 82) or in a dextran‐free medium (n = 48). All surgeries were performed by a single surgeon (I.G.). The surgeries were categorised according to whether the recipients' eyes had, or did not have, factors associated with an increased risk of graft detachment. Detachment rates were compared for all patients receiving the different kinds of graft, and only for those without risk factors.ResultsA significantly higher detachment rate was found among patients receiving pre‐cut grafts transported in a dextran‐containing medium (32.9%), compared to surgeon‐cut grafts (14.1%, p = 0.002), and pre‐cut grafts transported in a dextran‐free medium (6.3%, p = 0.002) for all recipients (those with and without risk factors for graft detachment). When analysing recipients without risk factors for graft detachment, the detachment rate was still significantly higher with pre‐cut tissue transported in a dextran‐containing medium (26.9%), compared to surgeon‐cut tissue (8.3%, p = 0.002) and pre‐cut tissue transported in a dextran‐free medium (3.6%, p = 0.01).ConclusionsThe use of pre‐cut DSAEK tissue transported in a dextran‐containing medium significantly increases the risk of graft detachment requiring re‐bubbling.