bluuebunny/crossref_metadata_2025_split huggingface dataset:
Live vaccines after pediatric solid organ transplant: Proceedings of a consensus meeting, 2018
Authors: Suresh Sneha , Upton Julia , Green Michael , Pham‐Huy Anne , Posfay‐Barbe Klara M. , Michaels Marian G. , Top Karina A. , Avitzur Yaron , Burton Catherine , Chong Pearlie P. , Danziger‐Isakov Lara , Dipchand Anne I. , Hébert Diane , Kumar Deepali , Morris Shaun K. , Nalli Nadya , Ng Vicky Lee , Nicholas Sarah Kogan , Robinson Joan L. , Solomon Melinda , Tapiero Bruce , Verma Anita , Walter Jolan E. , Allen Upton D. 
Published: September 2019

AbstractGrowing evidence suggests receipt of live‐attenuated viral vaccines after solid organ transplant (SOT) has occurred and is safe and needed due to lapses in herd immunity. A 2‐day consortium of experts in infectious diseases, transplantation, vaccinology, and immunology was held with the objective to review evidence and create expert recommendations for clinicians when considering live viral vaccines post‐SOT. For consideration of VV and MMR post‐transplant, evidence exists only for kidney and liver transplant recipients. For MMR vaccine post‐SOT, consider vaccination during outbreak or travel to endemic risk areas. Patients who have received antiproliferative agents (eg. mycophenolate mofetil), T cell–depleting agents, or rituximab; or have persistently elevated EBV viral loads, or are in a state of functional tolerance, should be vaccinated with caution and have a more in‐depth evaluation to define benefit of vaccination and net state of immune suppression prior to considering vaccination. MMR and/or VV (not combined MMRV) is considered to be safe in patients who are clinically well, are greater than 1 year after liver or kidney transplant and 2 months after acute rejection episode, can be closely monitored, and meet specific criteria of “low‐level” immune suppression as defined in the document.
A Swirl Cooling Flow Experimental Investigation on a Circular Chamber Using Three-Dimensional Stereo-Particle Imaging Velocimetry
Authors: Galeana Daisy , Beyene Asfaw 
Published: September 2019

Abstract
An experimental investigation is presented using three-dimensional (3-D) stereo-particle image velocimetry (stereo-PIV) of a swirl flow that models a gas turbine blade internal cooling configuration. The study is intended to provide an evaluation of the developments of the swirl cooling flow methodology utilizing the 3-D stereo-PIV. The objective is to determine the critical swirl number that has the potential to deliver the maximum axial velocity results. The swirl cooling flow methodology comprises cooling air channeling through the blade’s internal passages lowering the temperature; therefore, the experimental circular chamber is made of acrylic allowing detailed measurements and includes seven discrete tangential jets designed to create the swirl flow. An oil particle seeder (LAVision) is used to provide the particles for velocity measurements while the clear acrylic chamber allows visualization of the flow phenomena. The post-processed data are completed using davis, velocity calculations are conducted in matlab, and techplot is used for data visualization. The focus of this investigation is on the continuous swirl flow that must be sustained via continuous injection of tangential flow at three different Reynolds number, 7000, 14,000, and 21,000, where the swirl flow is generated with seven inlets. Important variations in the swirl number are present near the air inlets and decreases with downstream distance as predicted, since the second half of the chamber has no more inlets. The axial velocity reaches the maximum downstream in the second half of the chamber. The circumferential velocity decreases the downstream distance and reaches the highest toward the center of the chamber.
Conditional Reliability Analysis of a Semi-Submersible Mooring Line With Random Hydrodynamic Coefficients
Authors: Xu Sheng , Teixeira A. P. , Guedes Soares C. 
Published: September 2019

Abstract
In this paper, a detailed procedure to study the mooring line conditional strength reliability of a semi-submersible platform in a 100-year sea state is presented. A fully coupled analysis is conducted to calculate the mooring line tension of a deepwater semi-submersible floating system operated in the 100-year wave condition in South China Sea. 3-h extreme mooring line tensions are estimated by the average conditional exceedance rate (ACER) method from the data obtained by 10 and 20 min fully coupled dynamic simulations, and the results are validated by the global maximum method. A kriging metamodel is trained to predict the 3-h mooring line extreme tension taking into account the effect of random hydrodynamic drag coefficients. The hydrodynamic sampling points are generated by Latin hypercube sampling technique. A reliability analysis is carried out by Monte Carlo simulation considering the random hydrodynamic drag coefficients and mooring line breaking strength.
Teachers’ experiences of student feedback: A view from a department of social work in Sweden
Authors: Wallengren Lynch Michael 
Published: September 2019

INTRODUCTION: Course evaluations play a significant part in the facilitating of educational programmes at a university. Along with course evaluations, students are often asked for their reflections on teachers’ pedagogical methods and approaches. These types of questions canbe referred to as student evaluations of teaching, or SETs. Separately, there is growing, yet underdeveloped, interest in understanding the emotional impact the role of being a university lecturer has on the individual teacher. This piece of work is interested in combining the areasof teacher development, SET and emotional impact. Therefore, this research is seeking to understand how teachers in a department of social work engage with student feedback, manage this feedback and understand pedagogical self-development.METHODS: A mixed approach (an online survey and semi-structured interviews), was taken to gather the experiences of the teachers.FINDINGS: The results show that all the teachers engaged with student feedback. It also showed that some teachers experienced negative emotions regarding feedback that were unpleasant but had strategies to deal with the feedback.CONCLUSION: The results also pointed towards individual-directed solutions as the drivers behind creating good practices around pedagogical self-development, and for managing any emotional impact of SETs.
‘Mind the gaps’: the accessibility and implementation of an effective depression relapse prevention programme in UK NHS services: learning from mindfulness-based cognitive therapy through a mixed-methods study
Authors: Rycroft-Malone Jo , Gradinger Felix , Owen Griffiths Heledd , Anderson Rob , Crane Rebecca Susan , Gibson Andy , Mercer Stewart W , Kuyken Willem 
Published: September 2019

ObjectivesMindfulness-based cognitive therapy (MBCT) is an evidence-based approach for people at risk of depressive relapse to support their long-term recovery. However, despite its inclusion in guidelines, there is an ‘implementation cliff’. The study objective was to develop a better explanation of what facilitates MBCT implementation.SettingUK primary and secondary care mental health services.Design, participants and methodsA national two-phase, multi-method qualitative study was conducted, which was conceptually underpinned by the Promoting Action on Research Implementation in Health Services framework. Phase I involved interviews with stakeholders from 40 service providers about current provision of MBCT. Phase II involved 10 purposively sampled case studies to obtain a more detailed understanding of MBCT implementation. Data were analysed using adapted framework analysis, refined through stakeholder consultation.ResultsAccess to MBCT is variable across the UK services. Where available, services have adapted MBCT to fit their context by integrating it into their care pathways. Evidence was often important to implementation but took different forms: the NICE depression guideline, audits, evaluations, first person accounts, experiential taster sessions and pilots. These were used to build a platform from which to develop MBCT services. The most important aspect of facilitation was the central role of the MBCT implementers. These were generally self-designated individuals who ‘championed’ grass-roots implementation. Our explanatory framework mapped out a prototypical implementation journey, often over many years with a balance of bottom-up and top-down factors influencing the fit of MBCT into service pathways. ‘Pivot points’ in the implementation journey provided windows of either challenge or opportunity.ConclusionsThis is one of the largest systematic studies of the implementation of a psychological therapy. While access to MBCT across the UK is improving, it remains patchy. The resultant explanatory framework about MBCT implementation provides a heuristic that informed an implementation resource.
Iron stores in pregnant women with sickle cell disease: a protocol for a systematic review and meta-analysis
Authors: Aroke Desmond , Momo Kadia Benjamin , Njim Tsi 
Published: September 2019

IntroductionSickle cell disease (SCD) is the most common inherited disease worldwide. The greatest disease burden is seen in sub-Saharan Africa. Early diagnosis and improved care of people living with SCD have led to an increase in the number of women with SCD reaching the reproductive age. Iron deficiency anaemia remains the most common cause of anaemia in pregnancy, affecting 51%–63% of pregnancies in Africa. However, the unavailability of guidelines on supplementation of iron in this pregnant subpopulation often leaves clinicians in a fix. We propose to conduct the first systematic review and possibly a meta-analysis on the prevalence, associated factors and maternal/fetal outcomes of iron deficiency anaemia among pregnant women with SCD.Methods and analysisWe will search the following electronic databases for studies on the iron status of pregnant women with SCD: PubMed, MEDLINE, EMBASE, Google Scholar, African Journals Online, African Index Medicus, Popline and the Cochrane Library. After the selection of eligible studies from the search output, review of full text, data extraction and data synthesis will be performed. Studies obtained from the review shall be evaluated for quality, risk of bias and heterogeneity. Appropriate statistical methods shall be used to pool prevalence estimates for matching studies globally and in subpopulations. This protocol has been reported as per the 2015 guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols.Ethics and disseminationThere is no requirement for ethical approval as the proposed study will use published data. The findings of this study will be published in a peer-reviewed journal and will be presented at conferences.Trial registration numberCRD42018109803.
Agreement on the use of sensory screening techniques by nurses for older adults with cognitive impairment in long-term care: a mixed-methods consensus approach
Authors: Wittich Walter , Jarry Jonathan , Höbler Fiona , McGilton Katherine S 
Published: September 2019

ObjectiveBased on two scoping reviews and two environmental scans, this study aimed at reaching consensus on the most suitable sensory screening tools for use by nurses working in long-term care homes, for the purpose of developing and validating a toolkit.SettingA mixed-methods consensus study was conducted through two rounds of virtual electronic suitability rankings, followed by one online discussion group to resolve remaining disagreements.ParticipantsA 12-member convenience panel of specialists from three countries with expertise in sensory and cognitive ageing provided the ranking data, of whom four participated in the online discussion.Outcome measuresAs part of a larger mixed-methods project, the consensus was used to rank 22 vision and 20 hearing screening tests for suitability, based on 10 categories from the Quebec User Evaluation of Satisfaction with Assistive Technology questionnaire. Panellists were asked to score each test by category, and their responses were converted to z-scores, pooled and ranked. Outliers in assessment distribution were then returned to the individual team members to adjust scoring towards consensus.ResultsIn order of ranking, the top 4 vision screening tests werehand motion,counting fingers,confrontation visual fieldsand theHOT-V chart, whereas the top 4 hearing screening tests were theHearing Handicap Inventory for the Elderly, theWhisper Test, theMeasure of Severity of Hearing Lossand theHyperacusis Questionnaire, respectively.ConclusionsThe final selection of vision screening tests relied on observable visual behaviours, such as visibility of tasks within the central or peripheral visual field, whereas three of the four hearing tests relied on subjective report. Next, feasibility will be tested by nurses using these tools in a long-term care setting with persons with various levels of cognitive impairment.
What are the important morbidities associated with paediatric cardiac surgery? A mixed methods study
Authors: Brown Katherine L , Pagel Christina , Ridout Deborah , Wray Jo , Anderson David , Barron David J , Cassidy Jane , Davis Peter , Hudson Emma , Jones Alison , Mclean Andrew , Morris Stephen , Rodrigues Warren , Sheehan Karen , Stoica Serban , Tibby Shane M , Witter Thomas , Tsang Victor T 
Published: September 2019

ObjectivesGiven the current excellent early mortality rates for paediatric cardiac surgery, stakeholders believe that this important safety outcome should be supplemented by a wider range of measures. Our objectives were to prospectively measure the incidence of morbidities following paediatric cardiac surgery and to evaluate their clinical and health-economic impact over 6 months.DesignThe design was a prospective, multicentre, multidisciplinary mixed methods study.SettingThe setting was 5 of the 10 paediatric cardiac surgery centres in the UK with 21 months recruitment.ParticipantsIncluded were 3090 paediatric cardiac surgeries, of which 666 patients were recruited to an impact substudy.ResultsFamilies and clinicians prioritised:Acute neurological event, unplanned re-intervention, feeding problems, renal replacement therapy, major adverse events, extracorporeal life support, necrotising enterocolitis, postsurgical infection and prolonged pleural effusion or chylothorax.Among 3090 consecutive surgeries, there were 675 (21.8%) with at least one of these morbidities. Independent risk factors for morbidity included neonatal age, complex heart disease and prolonged cardiopulmonary bypass (p<0.001). Among patients with morbidity, 6-month survival was 88.2% (95% CI 85.4 to 90.6) compared with 99.3% (95% CI 98.9 to 99.6) with none of the morbidities (p<0.001). The impact substudy in 340 children with morbidity and 326 control children with no morbidity indicated that morbidity-related impairment in quality of life improved between 6 weeks and 6 months. When compared with children with no morbidities, those with morbidity experienced a median of 13 (95% CI 10.2 to 15.8, p<0.001) fewer days at home by 6 months, and an adjusted incremental cost of £21 292 (95% CI £17 694 to £32 423, p<0.001).ConclusionsEvaluation of postoperative morbidity is more complicated than measuring early mortality. However, tracking morbidity after paediatric cardiac surgery over 6 months offers stakeholders important data that are of value to parents and will be useful in driving future quality improvement.
Association between mid-upper arm circumference and cardiometabolic risk in Chinese population: a cross-sectional study
Authors: Hou Yanan , Jia Xu , Xuan Liping , Zhu Wen , Deng Chanjuan , Wang Long , Zhao Zhiyun , Li Mian , Lu Jieli , Xu Yu , Chen Yuhong , Wang Weiqing , Bi Yufang , Xu Min , Wang Tiange 
Published: September 2019

ObjectivesUpper body fat has been associated with an unfavourable cardiometabolic risk. We aimed to investigate the associations between mid-upper arm circumference (MUAC), a novel indicator of upper body fat, and a wide spectrum of cardiometabolic risk profiles in Chinese population.Design and settingCross-sectional analyses were performed using data from a well-defined community in 2014, Shanghai, China.ParticipantsA total of 6287 Chinese adults (2310 men and 3977 women) aged 40 years or older.Outcome measuresMultivariable logistic regression model was used to examine the associations of MUAC with cardiometabolic disorders including central obesity, diabetes, hypertension, hypertriglyceridaemia, low high-density lipoprotein (HDL) cholesterol and subclinical atherosclerosis.ResultsIn the overall participants, after multivariable adjustment, each 1 SD (3.13 cm) increment in MUAC was positively associated with central obesity (OR 2.05; 95% CI 1.85 to 2.28), hypertension (OR 1.10; 95% CI 1.03 to 1.19) and low HDL cholesterol (OR 1.10; 95% CI 1.01 to 1.22). Multivariable-adjusted ORs for subclinical atherosclerosis were gradually increased across increasing quartiles of MUAC with the lowest quartile as reference (quartile 2: OR 1.31; 95% CI 1.09 to 1.58; quartile 3: OR 1.33; 95% CI 1.10 to 1.62; quartile 4: OR 1.45; 95% CI 1.16 to 1.80; p for trend=0.005). Similar but more prominent associations were observed among women than men. In addition, MUAC was significantly interacted with diabetes (p for interaction=0.04) and insulin resistance (p for interaction=0.01) on subclinical atherosclerosis.ConclusionA greater MUAC was positively associated with higher risks of several cardiometabolic disorders and subclinical atherosclerosis in Chinese adults.
Effects of dental general anaesthesia treatment on early childhood caries: a prospective cohort study in China
Authors: Jiang Haofeng , Shen Lu , Qin Dan , He Songlin , Wang Jinhua 
Published: September 2019

ObjectivesTo evaluate the success rates of dental procedures, the recurrence rates of caries and changes in oral health-related quality of life (OHRQoL) in children following treatment for early childhood caries (ECC) under dental general anaesthesia (DGA) in Chongqing, China.DesignA single-centre prospective cohort study conducted from December 2016 to June 2017.SettingA tertiary stomatological hospital in Chongqing, China.ParticipantsA total of 159 children aged 2–5 years who received treatment for ECC under DGA were included.Main outcome measuresThe primary outcomes were the success rates of dental procedures (the number of successful procedures divided by the total number of procedures) and the recurrence rates of caries. The success and recurrence rates were evaluated by a specialised examiner. The secondary outcome was the change in children’s OHRQoL after DGA treatment, which was measured with the Early Childhood Oral Health Impact Scale (ECOHIS).ResultsOverall, 117 children (73.6%) and 101 children (63.5%) participated in 6-month and 12-month clinical examinations, respectively, and 151 children (95.0%) completed OHRQoL surveys pretreatment and at 1, 3, 6 and 12 months post-treatment. The resin composite, stainless steel crown, indirect pulp capping, pulpectomy, space maintenance and dental sealant success rates were 89.6%, 96.3%, 96.0%, 94.4%, 76.9% and 92.9%, respectively, at 6 months and 78.8%, 95.1%, 92.2%, 88.9%, 63.6% and 89.3%, respectively, at 12 months. 10 (8.5%) and 19 children (18.8%) developed recurrent caries within 6 and 12 months, respectively. Within 1 year of treatment, the total ECOHIS scores at each post-treatment time point were still significantly lower than those at pretreatment, although they had increased slowly over time.ConclusionsOverall, high success rates were obtained for the dental procedures, and the children’s OHRQoL significantly improved after treatment. However, there was a tendency towards caries relapse, and the children’s OHRQoL deteriorated over time.
Incidence and risk factors of depressive symptoms in 4 years of follow-up among mid-aged and elderly community-dwelling Chinese adults: findings from the China Health and Retirement Longitudinal Study
Authors: Wen Yue , Liu Chunjuan , Liao Jing , Yin Yiqiong , Wu Dongmei 
Published: September 2019

ObjectivesThe purpose of this study was to examine the incidence of depressive symptoms, and determine if baseline risk factors conferred a risk for incident depressive symptoms in nationally representative sample of mid-aged and elderly Chinese adults.DesignThis study was a secondary analysis of a prospective cohort from a nationally representative sample.SettingCommunity samples were recruited from the baseline survey of the China Health and Retirement Longitudinal Study. A four-stage, stratified, cluster probability sampling strategy was used, which included 10 257 households with members aged 45 years or older and their spouse.ParticipantsA total of 11 533 participants free of depressive symptoms at baseline were identified, and 10 288 were re-examined in either the first and/or the second follow-up surveys. The current analysis was conducted among the 10 288 participants.Primary and secondary outcome measuresDepressive symptoms were measured by the Center for Epidemiological Studies Depression Scale short form.ResultsThe findings showed that the incidence of depressive symptoms in a 4-year follow-up was as high as 22.3%. The incidence was much higher in rural areas (25.7%) and in women (27.9%). Furthermore, participants with 1 hour longer of night-time sleep had a 10% lower risk of developing depressive symptoms. Compared with individuals who perceived their health status as poor, those who perceived their health status as excellent had a 62% lower risk of developing depressive symptoms. In addition, having diabetes (OR=1.19), chronic kidney disease (OR=1.32), chronic digestive disorders (OR=1.15) and arthritis (OR=1.43) at baseline increased the risk of depressive symptoms. However, baseline body mass index was not associated with the subsequent depressive symptoms in this population.ConclusionsThis study highlights the importance of developing an appropriate screening test to identify depressive symptoms for those who are vulnerable and ensure these individuals can receive early interventions for depressive symptoms.