bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multicenter investigation of pediatric alimentary tract magnets ingestion in China
Authors: Wang Kai , Zhang Dan , Li Xianling , Wang Zengmeng , Hou Guangjun , Jia Xinjian , Niu Huizhong , Qi Shiqin , Deng Qingqiang , Jiang Bin , Bian Hongqiang , Yang Heying , Chen Yajun 
Published: October 2019

Abstract
Purpose: To describe the incidence and management of alimentary tract Buckyball ingestion in Chinese pediatric patients, and discuss the precautionary measures through a multicenter investigation.
Methods: Medical records of 74 pediatric patients from 9 large Chinese hospitals were included in this study. Questionnaires were distributed online, and medical records were reviewed. Follow-up was through telephone and outpatient service.
Results: Among the 74 cases were 50 boys (68%) and 24 girls (32%). The median age was 36 (22, 77) months, with a range of 7 months to 11 years old, and it showed two peaks. The annual case number showed a sharp increase, and the total case number in the last 2 years (2017 and 2018) showed a greater than 9-fold increase when compared with the first 2 years (2013 and 2014). The majority of ingestions were unintentional, with only 3 patients deliberately swallowing the Buckyball. The median time of ingestion until the onset of emergent symptoms was 2 (1, 5) days, and varied from 4 hours to 40 days. 21 patients had no symptoms, and the remaining cases presented with abdominal pain, vomiting, fever, abdominal distension, excessive crying, melena, and the ceasing of flatus and defecation. Gastroscopy, colonoscopy, laparoscopic surgery and laparotomy surgery were adopted according to the algorithm from the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). Gastrointestinal mucosa erosion, ischemia and necrosis, perforation, and abdominal abscess, ileus and fistula was found in the patients. The median number of Buckyballs ingested was 4 (2, 8), with a range from 1 to 39. During the follow-up period of 6 (1, 15) months, 3 patients had ileus, and one underwent a second operation. The remaining 71 patients were uneventful. None of the 74 patients reported a second swallowing of foreign bodies.
Conclusions: The incidence of pediatric alimentary tract magnets ingestion in China is still increasing. Management of such patients should follow the algorithm from NASPGHAN. Precautionary measures toward the issue should be taken from three levels, namely the national administration, producer, and consumer.
Keywords: Pediatric, Alimentary tract, Magnetic foreign body, Buckyball
Perioperative poor grip strength recovery is associated with 30-day complication rate after cardiac surgery discharge in middle-aged and older adults- a prospective observational study
Authors: Fu Liyuan , Zhang Yuanyuan , Shao Bohan , Liu Xiangjing , Yuan Bo , Wang Zhengqing , Chen Tienan , Liu Zhigang , Liu Xiaocheng , Guo Qi 
Published: October 2019

Abstract
Background: Although perioperative care during heart surgery has improved considerably, the rate of postoperative complications has remained stable. It has not been concluded how to better apply grip strength to clinical, postoperative complications. So our study aimed at researching the best way for using grip value for predicting early postoperative complications.
Methods: A total of 212 patients with mean age 63.8±6.3 who underwent cardiac surgery included participated in our study. We analyzed the ROC curve of grip strength, grip/weight and grip recovery with complications, found the best cutoff point. Logistic regression confirmed the correlation between grip strength grouping and complications.
Results: We found that 36 patients had 30-day complications. EuroSCORE were 2.15±1.52 and 2.42±1.58 between normal and complication groups, respectively. The area under the receiver-operating characteristic curve (AUC) of grip recovery take the most area (0.837, p<0.001), and the cutoff point was 83.92%. In logistic regression, lower grip recovery has higher risk impact on 30-day complications for 25.68 times than normal group, after adjusted surgery-related factors. After relisted characteristic information with grip recovery group , found that percentage of the estimated 6MWD (41.5 vs 48.3, p=0.028) and hospitalization time (7.2 vs 6.1, p=0.042) had worse trends in lower recovery group.
Conclusions: Poor grip recovery may be related to higher risk of postoperative complications within 30 days after discharge in middle-aged and older people independent of surgical risk. The results of this study provide a reference for the development of rehabilitation programs in the early postoperative recovery, and may also be a prognostic indicator for postoperative high-risk groups.
Breast self-examination practice and associated factors among female healthcare workers in West Shoa Zone, Western Ethiopia 2019: A cross-sectional study
Authors: Shallo seifadin Ahmed , Boru Jibril Dori 
Published: October 2019

Abstract
Abstract
Objective : Breast cancer is the leading cause of death among reproductive-age women worldwide and the second leading cause of death among women in Ethiopia. Regular breast self-examination is the most cost-effective methods for early detection of breast cancer. Despite this fact, breast self-examination was low among women in the general population and it was not well documented among health care workers. Therefore, this study intended to assess the magnitude of breast self-examination practice and associated factors among female healthcare workers in public health facility in West Shoa zone, Ethiopia. Institutional based cross-sectional study was conducted among 379 female healthcare workers. The study participants were recruited by lottery method. Data were collected from March to April 2019. Data were entered into Epi data version 4.5 and analyzed using SPSS version 25. Bivariate and multiple logistic regressions analysis were done. With 95% CI, significance level was decided at p-value≤ 0.05

Results: The magnitude of regular breast self-examination practice was 32.6%. Educational levels, breast cancer awareness, knowledge towards breast self-examination were predictors of breast self-examination. Regular awareness creation forum on breast self-examination technique, risk factors, and related matters should be facilitated so that all female health care workers will be reminded.
Drinking patterns and the distribution of alcohol-related harms in Ireland: Evidence for the prevention paradox
Authors: O'Dwyer Claire , Mongan Deirdre , Millar Seán R. , Rackard Marion , Galvin Brian , Long Jean , Barry Joe 
Published: October 2019

Abstract
Background

According to the prevention paradox, the majority of alcohol-related harms in the population occur among low-to-moderate risk drinkers, simply because they are more numerous in the population, although high-risk drinkers have a higher individual risk of experiencing alcohol-related harms. In this study we explored the prevention paradox in the Irish population by comparing alcohol-dependent drinkers (high-risk) to low-risk drinkers and non-dependent drinkers who engage in heavy episodic drinking (HED).Methods

Data were generated from the 2013 National Alcohol Diary Survey (NADS), a nationally representative cross-sectional survey of Irish adults aged 18–75. Data were available for 4338 drinkers. Respondents dependent on alcohol (as measured by DSM-IV criteria), respondents who engaged in monthly HED or occasional HED (1–11 times a year) and low-risk drinkers were compared for distribution of eight alcohol-related harms.Results

Respondents who were dependent on alcohol had a greater individual risk of experiencing each harm (p<.0001). The majority of the harms in the population were accounted for by drinkers who were not dependent on alcohol. Together, monthly and occasional HED drinkers accounted for 62% of all drinkers, consumed 70% of alcohol and accounted for 59% of alcohol-related harms.Conclusions

Our results indicate that the majority of alcohol consumption and related harms in the Irish population are accounted for by low- and moderate-risk drinkers, and specifically by those who engage in heavy episodic drinking. A population-based approach to reducing alcohol-related harm is most appropriate in the Irish context. Immediate implementation of the measures in the Public Health (Alcohol) Act (2018) is necessary to reduce alcohol-related harm in Ireland.
Longitudinal validity of using digital hand photographs for assessing hand osteoarthritis progression over 7 years in community-dwelling older adults with hand pain
Authors: Marshall Michelle , Jonsson Helgi , Helgadottir Gudrun , Nicholls Elaine , Myers Helen L , Jansen Victoria , Windt Danielle van der 
Published: October 2019

Abstract
Background : To determine the longitudinal construct validity of assessing hand OA progression on digital photographs over 7 years compared with progression determined from radiographs, clinical features and change in symptoms.
Methods: Participants were community-dwelling older adults (≥50 years) in North Staffordshire, UK. Standardized digital hand photographs were taken at baseline and 7 years, and hand joints graded for OA severity using an established photographic atlas. Radiographic hand OA was assessed using the Kellgren and Lawrence grading system. Hand examination determined the presence of nodes, bony enlargement and deformity. Symptoms were reported in self-complete questionnaires. Radiographic and clinical progression and change in symptoms were compared to photographic progression. Differences were examined using analysis of covariance and Chi-Square tests.
Results: Of 253 individuals (61% women, mean age 63 years) the proportion with photographic progression at the joint and joint group-level was higher in individuals with radiographic or clinical progression compared to those without, although differences were not statistically significant. At the person-level, those with moderate photographic progression over 7 years had significantly higher summed radiographic and clinical scores (adjusted for baseline scores) compared to those with no or mild photographic progression. Similar findings were observed for change in symptoms, although differences were small and not statistically significant.
Conclusion: Assessing hand OA on photographs shows modest longitudinal construct validity over 7 years compared with change in radiographic and clinical hand OA at the person-level. Using photographs to assess overall long-term change in a person with hand OA may be a reasonable alternative when hand examinations and radiographs are not feasible.
Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis
Authors: Enyew Habtamu Demelash , Beyene Abebe Hailu , Abebe Zewdu , Melese Addisu Dagnaw 
Published: October 2019

Abstract
Background: The concentration of fluoride in ground drinking water greater than the world health organization standard value imposes a serious health, social and economic problem in developing countries. In the Ethiopian Rift Valley where deep wells are the major source of drinking water, high fluoride level is expected. Though many epidemiological studies on fluoride concentration and its adverse effects have been conducted in the region, the result is highly scattered and needs systematically summarized for better utilization.
Objective: This research is aimed at estimating the pooled level of fluoride concentration in ground drinking water and the prevalence of dental fluorosis among Ethiopian rift valley residences.
Methods: Cochrane library, MEDLINE/PubMed and Google scholar databases were searched for studies reporting the mean concentration of fluoride in ground water and prevalence of dental fluorosis in Ethiopian Rift valley. Search terms were identified by extracting key terms from reviews and selected relevant papers and review medical subject headings for relevant terms.
Results: The mean fluoride level in ground water and the prevalence of dental fluorosis were pooled from eleven and nine primary studies conducted in Ethiopian Rift Valley respectively. The pooled mean level of fluoride in ground water therefore was 6.03 mg/l (95% CI; 4.72–7.72, p < 0.001) and the pooled prevalence of dental fluorosis among residents in Ethiopian rift valley was 32% (95% CI: 25, 39%, p<0.001), 29% (95% CI: 22, 36%, p<0.001) and 24% (95% CI: 17, 32%, p<0.001 for mild, moderate and sever dental fluorosis respectively. The overall prevalence of dental fluorosis is 28% (95% CI: 24, 32%, p<0.001).
Conclusions: Though, the concentration level varies across different part of the rift valley region, still the level of fluoride in ground drinking water is greater than the WHO standard value (1.5mg/l). Relatively high-level pooled prevalence of dental fluorosis was also seen in Ethiopian rift valley. Therefore, further studies covering the temperature, exposure time and other intake path ways with large sample size is recommended. Interventional projects should be implemented to decrease the concentration of fluoride in the ground drinking water source.
Key words: Dental fluorosis, Fluoride, Concentration, Rift Valley, Ethiopia
Comparative analysis of IGFBP-3 gene sequence in Egyptian sheep, cattle, and buffalo
Authors: Saleh Ahmed Abdel-kader , Rashad Amr M.A. , Hassanine Nada. N.A.M. , Sharaby Mahmoud A. , Zhao Yongju 
Published: October 2019

Abstract
Objective: A total of 205 animals from four Egyptian livestock species; cattle (n=18), buffaloes (n=12), sheep (n=150) and goats (n=25) were used in this study to detect polymorphism and perform comparative analysis for IGFBP-3 gene using DNA sequencing and (PCR-RFLP).
Results: The amplified fragments were found to be of length 654 bp in sheep, 651bp in cattle and 655 bp in buffalo. For Falahy goats, PCR was performed to amplify a 316 bp fragment from exon 2 of the IGFBP-3 gene. The digestion of 654 bp with HaeIII restriction enzyme yielded a single restriction pattern for goats, while for cattle, 3 genotypes were identified; (AA),(AB), and (BB). Moreover, for buffalo one genotype (AA) only was found with HaeIII and TaqI restriction enzymes, separately. Also, the digestion profile for goats with HaeIII revealed one pattern only. Nucleotide sequencing of the amplified fragments of IGFBP-3 gene in sheep, cattle, buffalo, and goat was submitted to the NCBI GenBank (Accession no. MG738671.1, MG738673.1, MG738674.1, and MG738672.1, respectively). The nucleotide sequencing analysis indicated similarity percentages in IGFBP-3 gene fragments of 88.54, 89.63 and 95.06 % between ''sheep and cattle '', ''sheep and buffalo '', and ''cattle and buffalo'', respectively.
Predictors of very preterm births (born between 23 and 29 weeks’ gestation) at a tertiary care center in Karachi, Pakistan: additional multivariate analyses on data from primary cohort
Authors: Yakoob Mohammad 
Published: October 2019

Abstract
Objective: Previously, we have published univariate analyses on a cohort of all singleton, very preterm infants (N=101) born between 23 and 29 weeks of gestation during January 01, 1998 to June 30, 2003 at The Aga Khan University Hospital in Karachi, Pakistan. Our main objective was to extend these analyses to multivariate logistic regression models and report Odds Ratios (ORs) for univariate and multivariate analyses. All variables in univariate were included in multivariate models.
Results: The survival incidences were 0% at 23, 16.7% at 24, 40.0% at 25, 30.0% at 26, 33.3% at 27, 68.8% at 28 and 83.9% at 29 weeks of gestation. In univariate analyses, gestational age, birth-weight and mode of delivery (Cesarean-section had higher survival compared to vaginal) were statistically significant predictors of survival (P≤0.001 each). Other variables that also included antenatal steroids did not achieve significance. However, in complete-case multivariate analyses, only gestational age (per week) was associated with survival (OR=2.5, 95% CI: 1.1–5.5, P=0.03); birth-weight (per 100 grams) and C-section were not associated-1.2, 0.88–1.6, P=0.26 and 2.4, 0.48–12.2, P=0.28. Antenatal steroid use, maternal age, year of birth, parity, history of preterm delivery, hemoglobin levels, complications and time of birth remained not associated.
Morphological, molecular and pathological appraisal of Hymenolepis nana (Hymenolepididae) infecting laboratory mice Mus musculus
Authors: Al-Olayan Ebtsam , Abdel-Gaber Rewaida , Aloufi Abeer , Alanazi Zainab 
Published: October 2019

Abstract
Background: Hymenolepis nana , commonly found parasite in mice colonies maintained under conventional conditions, has zoonotic potential and is characterised by autoinfection and direct life cycle.
Results: This study intended to determine parasitic infection rate in laboratory mice. Of the 50 mice, 40.0% were found to be infected with hymenolepidid cestode. Infection rate was higher in males (52.0%) than in females (28.0%). Light and scanning electron microscopic studies of cestode parasite revealed that the worms were medium-sized; had globular scolex with four suckers, a retractable rostellum equipped with 20-30 hooks, and a short unsegmented neck; remaining strobila consisted of immature, mature, and gravid proglottids; irregularly alternating genital pores; lobulated ovary; post-ovarian vitelline gland; and uterus containing ˃200 small eggs in gravid proglottids. Molecular characterisation based on mitochondrial COX1 gene sequence analysis used to confirm taxonomy of the parasite. The parasite showed identity ˃80.0% with other species available in GenBank. High blast scores and low divergence were noted between isolated parasite and previously described H. nana (gb| AP017666.1). Phylogenetic analysis using COX1 sequence place this hymenolepidid species within Cyclophyllidea.
Conclusions: The present species was found to be deeply embedded in the genus Hymenolepis with close relationships to other H. nana as a putative sister taxon.
Analysis of Segregation Ratio Distortion and Linkage Mapping in Two Switchgrass F1 Populations: Lowland-lowland and Lowland-upland Using Genotyping by Sequencing Data
Authors: Razar Rasyidah , Devos Katrien , Missaoui Ali 
Published: October 2019

Abstract
Background: Switchgrass is an emerging bioenergy crop due to its perennial nature, high biomass yield, and ability to grow in marginal land. The high genetic diversity in switchgrass germplasm can be exploited to capture favorable traits that increase the range of adaptation and biomass yield. Genetic diversity can be explored using single nucleotide polymorphisms (SNPs) that next-generation sequencing has made possible for high-throughput genotyping. We used genotyping-by-sequencing (GBS) of genomic fragments resulting from two methylation sensitive restriction enzymes: PstI and MspI . Two bi-parental F1 populations were developed from crosses between lowland B6 and lowland AP13 (AB population), and lowland B6 with upland VS16 genotypes (BV population), with a target number of 298 progenies in each population. Pseudo-testcross strategy was adopted to perform linkage analysis in these populations that are segregating for winter dormancy using single dose markers (SDA): heterozygous in one parent and homozygous in the other parent. We compared the amount of polymorphisms between the two crosses and examined the pattern of segregation distortion based on the SNPs data generated. Results: Two genetic maps were generated for each population, with 2772 markers in AB and 3766 markers in BV. The higher number of markers in the BV population was expected for since the parents originated from different ecotypes and verified to have the highest genetic distance. More segregation distortion was observed in markers located in the telomeric regions where more genes reside. More markers from the AB population exhibited segregation distortion compared to the BV, and the proportion of heterozygous alleles were significantly higher than homozygous alleles in AB population. The linkage maps showed strong collinearity with P. virgatum V5.1 reference genome with a very minimal number of markers originating from different chromosomes. Conclusion: Understanding the extent of segregation distortion in switchgrass crosses is important for the correct inclusion of markers based on their segregation ratio when constructing a linkage map. Switchgrass linkage maps should be a useful resource to dissect beneficial biomass traits linked to SNP markers.
Treatment with radiosynoviorthesis in hemophilic patients with and without inhibitor
Authors: Sanabria Mario Edgar Tena , Sato Y. Rojas , Resendiz J.C Castañeda , Herrera G. Fuentes 
Published: October 2019

Abstract
Background. Spontaneous bleedings occurring into joints (hemarthrosis) are the most common manifestations of hemophilia and causes severe joint damage ultimately resulting in joint disfunction known as hemophilic arthropathy. Among available therapeutic options for reducing recurrent hemarthrosis-associated damage, radiosynoviorthesis (RS) has proven effective in improving joint function. Aim. To assess the impact of RS with Yttrium 90 (90Y) on frequency of hemarthroses, need for prophylaxis and joint function in a group of pediatric patients, as well as on costs for hospitalization. Methods . Between November 1998 and February 2017, we evaluated 27 pediatric patients with mild, moderate or severe hemophilia with haemophilic arthropathy. Patients suffered between two and five episodes of hemarthrosis per month. Overall, RS was applied in 60 joints. All patients but 3 received one single intra-articular injection with 90Y. Results. During the follow-up, one patient showed a recurrent joint bleeding 15 months after RS wit 90Y, one patient after 12 months and one patient after 45 days. Both costs of hospitalization and need for prophylaxis were reduced. Conclusion. RS with 90Y is a simple and safe treatment for recurrent hemarthrosis in patients with hemophilia. It decreases the use of factor VIII / IX and improves joint function.
Welfare and Wealth in Iran: Rural and Urban Dichotomies
Authors: Shafiei Sediqe , Yazdani Shahram , Zafarmand A Hamid , Jadidfard Mohammad-Pooyan , Shakerian sareh 
Published: October 2019

Abstract
Objective : Increasing social welfare and reducing poverty are to ensure the well-being of all classes of a society. Cities and villages are distinguished by cultural and economic disparities. The purpose of this study was to develop and present a comprehensive model on welfare and wealth components and their relationship with each other , as well as determining the contributing factors and variables affecting them by presenting a comprehensive model.
Results : The Structural Equation Modeling ( SEM ) method was used to analyze the data and investigate the causal relationship of latent variables. Observed variables and latent variables of the model were analyzed and tested by using AMOS and SPSS (version 21) statistical methods, in two exploratory and confirmatory steps. Wealth and welfare were identified as two separate subjects in the conceptual model and in the final structural model for rural households. Unlike, in the urban community, they were recognized as a single category in the final structural model. The results of this study can provide the clear hints for effective policy making to break the cycle of deprivation and poverty in Iranian rural and urban population.