bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Tari Ayam Modifikasi Terhadap Perkembangan Motorik Kasar Anak di Taman Kanak-Kanak Jabal Rahmah Padang
Authors: Oktari Henifo , Marlina Serli 
Published: July 2019

<p>This research begins with the challenge of implementing gross motor development that has not supported coordinated body movement. This study aims to find out how to change the gross motoric skills of children in Jabal Rahmah Padang Kindergarten. This study uses quantitative compilation of Quasi Eksperiments. The study population was all children in Jabal Rahmah Padang Kindergarten, and the Purvosive Sampling sampling technique, namely classes B1 and B2 each of which could be contacted by 10 children. Thehtechniquehofhcollectinghdatahusinghahtesthconsists of 5 points of approval and a data collection tool using the approving sheet.hThenhthehdatahishprocessed by the difference test (t-test). Based on the data analysis, the average experimental class test is 85 and SD is 8.06 while the control class 77 and SD is 6,78 in the hypothesis testing obtained by tcount (2,279 and t<sub>table </sub>of 2,100 at the real level = 0,05 and dk = 18. It can be concluded that the use of modified chicken dance opposes the gross motor development of children in Jabal Rahmah Padang Kindergarten 2018/2019.</p>
A Cross-Sectional Study of Job Burnout, Psychological Attachment, and the Career Calling of Chinese Doctors
Authors: Zhang Shu'e , Wang Jinghui , Xie Fengzhe , Yin Dong , Shi Yu , Zhang Min , Li Fujun , Yang Libin , Cao Depin , Sun Tao 
Published: July 2019

Abstract
Background: The main objectives of this study were as follows: (1) evaluate the prevalence of burnout syndrome among doctors, (2) establish associations with demographic factors in China, and (3) examine the mediating role of psychological attachment in the relationship between job burnout and career calling.
Methods:This cross-sectional survey was conducted by administering an online questionnaire in May 2016. The survey was performed across Thirty provinces. In total,A total of 3,016 Chinese doctors were selected as participants, of which 2,617 completed valid questionnaires (effective response rate: 86.77%).
Results: The overall prevalence of burnout symptoms among Chinese doctors was 85.79%. Little variance was reported for burnout symptoms according to age (Wald2 = 6.843, P < 0.05, OR <1 ), professional title (Wald2 = 13.110, P < 0.05, OR > 1), and working hours (Wald 2= 7.226, P < 0.05, OR > 1). However, the burnout of Chinese doctors was found to be associated with psychological attachment (B = -0.6433, P < 0.0001) and career calling (B = 0.3653, P < 0.0001); furthermore, psychological attachment (B = 0.2350, P < 0.001) mediated the relationship between job burnout and career calling.
Conclusion: Burnout symptoms among Chinese doctors were prevalent and associated with age, professional title, and long working hours. Chinese doctors aged 20-30 experienced a much higher level of burnout symptoms. The longer hours doctors worked, the more likely they were at risk of burnout symptoms, especially among attending physicians. Doctors who endured high-level burnout tended to exhibit decreasing psychological attachment, which threatened their sense of career calling. Finally, this paper proposed related explanations for the function mechanisms based on both theoretical and practical perspectives.
Low STMN1 is associated with better prognosis in Asian patients with esophageal cancers: a meta-analysis
Authors: Cao Shasha , Zhang Wei , Shen Peihong , Xu Ruiping 
Published: July 2019

Abstract
Background

The role of STMN1 in the development and progression of esophageal carcinoma is not yet determined. The present study aimed to systematically evaluate the correlation between STMN1 and prognosis of patients with esophageal carcinoma.

Methods

Electronic databases including PubMed, Embase, the Cochrane library, and Chinese Biomedical Literature Database (CBM) were searched to identify studies evaluating the impact of STMN1 on the survival of esophageal cancer patients, without the language limitation. Two investigators screened the literature according to the inclusion and exclusion criteria and evaluated the quality of the included studies. The combined analysis was performed using RevMan5.3 software.

Results

A total of 8 studies, involving 1240 esophageal carcinoma patients, were included in this retrospective design. Meta-analysis showed that esophageal carcinoma patients with low STMN1 had a superior overall survival (OS) and disease-free survival (DFS) than those with high expression of STMN1. Compared to the high expression of STMN1, the 5-year survival rate was significantly higher in patients with low level of STMN1. Patients with high STMN1 expression had a higher risk of experiencing clinical grade III-IV disease, lymph node metastasis, and tumor invasion than those with low STMN1.

Conclusion

STMN1 is an indicator for the prognosis of esophageal carcinoma patients.
A Bayesian mesh meta-analysis of medicine treatment in patients with enuresis
Authors: Han Tao , Chen Shujing , Li Yuan , Gong Jinchao , Zhang Xiaoning 
Published: July 2019

Abstract
Background

The aim of this study was to comprehensively evaluate the efficacy of multiple methods for enuresis and chose optimal treatment plan.

Methods

We searched Pubmed, Embase and Cochrane Library for included articles. All data were analyzed comprehensively using aggregate data drug information system (ADDIS) software (1.16.5). The random effects model was used for all test models. Node-splitting analysis and inconsistency standard deviation (ISD) were applied for consistency test. For node-splitting analysis (NSA) with Pb > 0.05, consistency model was chosen for analysis. Otherwise, the inconsistency model was used.

Results

Twenty-one studies were included in this meta-analysis. For the response rates, desmopressin acetate tablets (dDAVP) + Tolterodine (Tol), dDAVP + Imipramine (Imi), Imi + oxybutynin (Oxy), and Imi + Pseudoephedrine (Pse) treatment were the best, while the efficacy of Verapamil (Ver), Mianserin (Mia) and Estradiol (Est) were the worst. For the mean number of nocturia indicator, the effects of dDAVP + Imi and dDAVP + Tamsulosin (Tam) treatment were the best, while the efficacy of Imi was the worst. For nocturnal urine volume, the effects of dDAVP + Oxy and dDAVP + Tam were the best, while the efficacy of Pse and Tam were the worst. However, the difference between the groups was not statistically significant (P > 0.05). For adverse effects index, the incidence of adverse effects of Est and dDAVP + Imi was the lowest, the incidence of Ver was the highest.

Conclusions

The effects of dDAVP + Imi and dDAVP + Tam were the best, while Ver was with the worst efficacy.
Risk factors for intra-abdominal abscess following laparoscopic appendectomy for acute appendicitis: a retrospective cohort study on 2,076 patients
Authors: Tartaglia Dario , Fatucchi Lorenzo Maria , Mazzoni Alessio , Miccoli Mario , Piccini Lorenzo , Cengeli Ismail , Cobuccio Luigi , Bertolucci Andrea , Pucciarelli Marsia , Galatioto Christian , Saverio Salomone Di , Chiarugi Massimo 
Published: July 2019

Abstract
Background. Intra-abdominal abscesses (IAA) may develop after laparoscopic appendectomies (LA) for acute appendicitis. The identification of risk factors for postoperative IAA could lead to a decrease in the readmission rate and surgery redoes after LA for acute appendicitis.
Materials and methods. We reviewed 2,076 patients managed via a LA for acute appendicitis between 2001 and 2017. Male gender accounted for 53.5% of patients. Mean age was 29.5 (SD ± 18.47) years. Thirty-seven patients (1.8%) developed a postoperative IAA. Comparison between groups was made via univariate and multivariate analyses.
Results. Male gender (p<0.05), ASA score ≥ 2 (p<0.05), a gangrenous or perforated appendicitis (p<0.0001), abscess or pelvic peritonitis (p<0.0001), clipping the mesoappendix (p<0.0001), appendix division by mechanical stapler (p<0.05), and prolonged antibiotic therapy (p<0.01) were significantly more frequent in the group of patients with IAA. In terms of multivariate analysis, only pelvic peritonitis (p < 0.005), a perforated appendicitis (p <0.05), and clipping the mesoappendix (p < 0.0001) were independent predictive factors for postoperative IAA
Conclusion. Patients with peritonitis or a perforated appendicitis, and those who had their mesoappendix clipped showed a higher likelihood of developing an IAA. At-risk patients should be provided with careful follow-up for the early detection and management of this complication.
Two-year outcome of an eye that underwent hyperopic LASIK following inadvertent myopic SMILE lenticule in situ implantation
Authors: Zhao Jing , Shang Jianmin , Niu Lingling , Xu Haipeng , Yang Dong , Zhao Yu , Fu Dan , Zhou Xingtao 
Published: July 2019

Abstract
Background: This report describes a case in which hyperopic femtosecond laser-assisted in situ keratomileusis (FS-LASIK) was performed following small incision lenticule extraction (SMILE) lenticule in situ implantation.
Case presentation: The hyperopic left eye of a 46-year-old patient with refraction of +7.75 diopters sphere (DS)/-1.25 diopters cylinder (DC)  5° and corrected distance visual acuity (CDVA) of 20/50 mistakenly underwent the SMILE procedure for myopic astigmatism (-8.50 DS/-1.50 DC  175°) due to medical negligence. The extracted lenticule was subsequently re-implanted in situ. After 8 months, the left eye underwent FS-LASIK to correct hyperopia and astigmatism (+5.0 DS/-0.75 DC × 100°). Two years after FS-LASIK, corneal tomography showed no ectasia and microscopy revealed transparent cornea. The left eye exhibited CDVA of 20/50 with refraction of -0.75 DS/-0.25 DC × 165°.
Conclusions: SMILE lenticule in situ implantation offers a solution for corneal volume and thickness restoration. In addition, FS-LASIK provides feasible and effective correction of refractive error following lenticule re-implantation.
TOXIC ANTERIOR SEGMEN SYNDROME PASCA SMALL INCISION CATARACT SURGERY: LAPORAN KASUS
Authors: Mahanani Esti , Mabrouka Alia , Mabrouka Alia 
Published: July 2019

Toxic anterior segmen syndrome (TASS) adalah suatu komplikasi inflamasi
segmen anterior yang bersifat akut, steril, dan non infeksius yang bisa terjadi pada
semua jenis operasi di segmen anterior. Kondisi ini mempunyai gambaran klinis
yang mirip dengan endoftalmitis infeksius pada awal pasca operasi. Laporan
kasus ini melaporkan suatu kasus TASS yang terjadi 20 jam pasca small incision
cataract surgery. Kasus ini memberikan prognosis baik dengan terapi steroid
topikal yang intensif
Sustainable hydrogen production from seawater and sewage treated water using reverse electrodialysis technology
Authors: Higa Mitsuru , Watanabe Takeshi , Yasukawa Masahiro , Endo Nobutaka , Kakihana Yuriko , Futamura Hidenobu , Inoue Katsuhiro , Miyake Haruo , Usui Jiro , Hayashi Azusa , Matsuhashi Manabu 
Published: July 2019

Abstract
A pilot-scale sustainable hydrogen production system using reverse electrodialysis (RED) technology was launched. The system is based on direct conversion of salinity gradient energy (SGE) between seawater (SW) and sewage treated water (STW) to hydrogen production by water electrolysis. The hydrogen production rate was almost the same as the theoretical value. This indicates that the RED hydrogen production system can convert SGE between SW and STW to hydrogen energy at high current efficiency.
Study on the treatment of simulated azo dye wastewater by a novel micro-electrolysis filler
Authors: Sun Zhen-Zhu , Liu Zhong-Hai , Han Le , Qin Dong-Ling , Yang Gang , Xing Wei-Hong 
Published: July 2019

Abstract
A new type of iron-copper-carbon (Fe-Cu-C) ternary micro-electrolysis filler was prepared with a certain proportion of iron powder, activated carbon, bentonite, copper powder, etc. The effect of the new type of micro-electrolysis filler on the simulated methyl orange dye wastewater was studied. The effects of various operational parameters, such as reaction time, initial pH value, aeration rate, filler dose and reaction temperature, on the degradation rate of methyl orange were studied to determine the optimum treatment conditions, and the micro-electrolysis filler was characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD). The experimental results show that the degradation rate of 220 mL of simulated dye wastewater with a concentration of 100 mg/L reached 93.41% ± 2.94% after 60 mL/min of aeration, with an initial pH = 2, a dose of 45 g and 125 minutes of reaction at room temperature. The new micro-electrolysis filler has a high degradation rate for methyl orange solution, which is attributed to the iron and activated carbon particles sintered into an integrated structure, which makes the iron and carbon difficult to separate and affects the galvanic cell reaction. The addition of copper also greatly increases the transmission efficiency of electrons, which promotes the reaction. In addition, the surface iron is consumed, the adjacent carbon is stripped layer by layer, and the new micro-electrolytic filler does not easily passivate and agglomerate during its use.
Mitochondrial Injury and Targeted Intervention in Septic Cardiomyopathy
Authors: Tan Ying , Chen Sainan , Zhong Jiankai , Ren Jun , Dong Maolong 
Published: July 2019

Background:Sepsis and septic shock are known to prompt multiple organ failure including cardiac contractile dysfunction, which is typically referred to as septic cardiomyopathy. Among various theories postulated for the etiology of septic cardiomyopathy, mitochondrial injury (both morphology and function) in the heart is perceived as the main culprit for reduced myocardial performance and ultimately heart failure in the face of sepsis.Methods:Over the past decades, ample of experimental and clinical work have appeared, focusing on myocardial mitochondrial changes and related interventions in septic cardiomyopathy.Results and Conclusion:Here we will briefly summarize the recent experimental and clinical progress on myocardial mitochondrial morphology and function in sepsis, and discuss possible underlying mechanisms, as well as the contemporary interventional options.
Gut Microbiota, Obesity and Bariatric Surgery: Current Knowledge and Future Perspectives
Authors: Cӑtoi Adriana Florinela , Vodnar Dan Cristian , Corina Andreea , Nikolic Dragana , Citarrella Roberto , Pérez-Martínez Pablo , Rizzo Manfredi 
Published: July 2019

Background::There is an urgent need for a better understanding and management of obesity and obesity- associated diseases. It is known that obesity is associated with structural and functional changes in the microbiome.Methods::The purpose of this review is to present current evidence from animal and human studies, demonstrating the effects and the potential efficacy of microbiota modulation in improving obesity and associated metabolic dysfunctions.Results::This review discusses possible mechanisms linking gut microbiota dysbiosis and obesity, since there is a dual interaction between the two of them. Furthermore, comments on bariatric surgery, as a favourable model to understand the underlying metabolic and inflammatory effects, as well as its association with changes in the composition of the gut microbiota, are included. Also, a possible impact of anti-obesity drugs and the novel antidiabetic drugs on the gut microbiota has been briefly discussed.Conclusion::More research is needed to better understand here discussed the association between microbiota modulation and obesity. It is expected that research in this field, in the following years, will lead to a personalized therapeutic approach considering the patient’s microbiome, and also give rise to the discovery of new drugs and/or the combination therapies for the management of obesity and obesity-related co-morbidities.
Drug Levels and Antibodies Against TNF-blockers in Spondyloarthritis and Rheumatoid Arthritis are Associated with the Activity but they do Not Predict it
Authors: Padilla-Martínez Erika Marcela , Romero-Sanchez Consuelo , Bello-Gualtero Juan Manuel , Mesa-Betancourt Ana Maria , Bautista-Molano Wilson , Valle-O Rafael 
Published: July 2019

Background:
Many patients may have resistance to TNF-blockers. These drugs may induce
neutralizing antibodies. The determination of the drug levels of TNF-blockers and Anti-Drug
Antibodies (ADAs) against TNF-blockers may help to make clinical decisions.

Objectives:
The objective of this study was to associate and predict the drug levels of TNFblockers
and ADAs in relation to disease activity in patients with Spondyloarthritis (SpA) and
Rheumatoid Arthritis (RA).

Methods:
Cross-sectional study including patients fulfilling ASAS classification criteria for SpA
and 2010 ACR-EULAR classification criteria for RA. These patients were treated with Adalimumab
(ADA), Infliximab (IFX), and Etanercept (ETN). A bivariate analysis and the chi-square test
were performed to evaluate the association of ADAs and drug levels with activity measures for
SpA and RA. Five regression models analyzing drug levels, ADAs and disease activity measures
using a multiple linear regression were performed in order to evaluate the prediction of ADAs and
drug levels in relation to disease activity.

Results:
In SpA, IFX levels were associated with BASDAI (Bath Ankylosing Spondylitis Disease
Activity Index) (p=0.034). In RA, total drug levels were associated with DAS28-ESR (28 joint
Disease activity Score-erythrocyte sedimentation rate), (p=0.008), DAS28-CRP (p=0.042), CDAI
(Clinical Disease Activity Index) (p=0.047) and SDAI (Simple Disease activity index), (p=0.017).
ADA levels had association with CDAI (p=0.002) and SDAI (p=0.002). IFX levels were associated
with a DAS28-ESR (p=0.044), DAS28-CRP (p=0.022) and SDAI (p=0.022). ADAs were associated
in SpA with BASDAI (p=0.027). Drug levels and ADAs did not predict disease activity in
patients with SpA or RA.

Conclusions:
ADAs and drug levels of anti-TNF are associated with disease activity measures in
patients with SpA and RA. However, they cannot predict clinical activity in these conditions.
Comparison of the Analgesic Effect of Intravenous Ketamine versus Intravenous Morphine in Reducing Pain of Renal Colic Patients: Double-Blind Clinical Trial Study
Authors: Forouzan Arash , Masoumi Kambiz , Motamed Hassan , Esfahani Seyed Reza Naji , Delirrooyfard Ali 
Published: July 2019

Background:
The effective relief of renal colic patients with low complications is one of
the important concerns of emergency physicians. The aim of this study was to investigate the use of
injectable ketamine as an alternative to routine drugs in the relief of pain in patients with renal colic.

Methods:
This double-blind clinical trial was conducted on patients who had suffered kidney pain
due to kidney stones in 2017, referred to Ahvaz Imam Khomeini Hospital. Patients were divided into
2 groups: the first group received intravenous ketamine (0.3 mg/kg) and the second group received
intravenous morphine (0.1 mg/kg) in a double-blind form. Finally, the mean pain was evaluated before
injection, after 10, 20, 30, and 60 minutes as the initial result while the side effects were considered
as secondary results.

Results:
In this study, 135 patients with renal colic participate in this study. The mean pain at the
time of referral to the hospital in the group receiving morphine and ketamine was 9.2 and 9.2, respectively,
which did not show any significant difference. Based on these findings, there was no significant
difference between the factors evaluated during the study of the two groups. Only in the ketamine
group, there were 3 cases of nausea and 1 of vomiting. However, there was a significant increase
in the need for additional doses of fentanyl in the morphine recipient group (p = 0.02).

Conclusion:
The findings suggest that the use of ketamine can produce a more rapid relief effect,
and decrease the use of opioids which create various complications, including nausea and vomiting in
patients, especially patients with renal colic.
Empowered AODV Protocol in Wireless Sensor Network using Three Variable RSA Cryptosystem
Authors: Agarwal Amit K. , Chandra Munesh , Sarangdevot S.S. 
Published: July 2019

Background:
The Wireless Sensor Network (WSN) is a type of networks which primarily
designed for the purpose of monitoring in remote areas. It consists of communicating nodes (called
sensor's) which communicate each other to share their data and passing the information to the central
node. In many applications like defence requires the secure communication of information. However,
due to the numerous characteristics of WSN such as open shared communication channel, limited
memory, and processing power of sensors, etc. these networks are vulnerable to various attacks such
as black hole, gray hole, etc.

Objective:
The objective of the paper is to secure the AODV routing protocol in WSN using cryptography
techniques.

Methods:
In this paper, the Ad hoc On-demand Distance Vector (AODV) routing protocol has been
chosen for information routing because of their lightweight processing capability. To provide secure
communication in WSN, the AODV routing protocol is secured by utilizing the RSA key generation
algorithm. Here, RSA with three variables (three prime numbers) is employed instead of two variables.

Results:
The effectiveness of the proposed approach in handling black hole attack is being verified
through the simulation results obtained from the experiments conducted using Network Simulator
tool (NS2). The three popular performance metrics namely Average End-to-End Delay, Packet Delivery
Ratio, and Average Throughput are used for evaluation purpose. These results are observed
under different pose time and varying number of malicious nodes.

Conclusion:
In this paper, a new three variable RSA cryptosystem-based security model is proposed
to protect the communication against the Black Hole (BH) attack in wireless sensor networks. The
use of three variables instead of two variables allows our model to provide more security as compared
to other methods. Simulation results obtained from the experiments carried out using NS2 tool
evident the performance of the proposed model over original AODV and other previous models.
DIFFERENTIATION OF BOVINE AND PORCINE GELATINES USING LC-MS/MS AND CHEMOMETRICS
Authors: SALAMAH NINA , ERWANTO YUNY , MARTONO SUDIBYO , MAULANA IRFAN , ROHMAN ABDUL 
Published: July 2019

Objective: To differentiate porcine gelatin and bovine gelatins using specific peptide markers as determined by liquid chromatography-mass spectrometry tandem with mass spectrometry (LC-MS/MS) and classify both gelatins using retention time and m/z as variables in principal component analysis (PCA).
Methods: Porcine and bovine gelatins were digested using trypsin enzyme and then subjected to LC-MS/MS analysis. The specific peptides were identified. The classification between porcine and bovine gelatins was carried out using chemometrics of PCA using retention times and mass to charge ratio (m/z) as variables.
Results: PCA using singvariables retention times (tR) and m/z could successfully classify porcine gelatin and bovine gelatin based on score plots of first principle component (PC1) and second principle component (PC2). The loading plot analysis showed that variable of tR32 and m/z32 contributed for the separation of both gelatins.
Conclusion: The chromatograms of LC-MS/MS combined with PCA offered reliable method for differentiation between porcine and bovine gelatins. The developed method could be extended for halal authentication of food and pharmaceutical products via detection of porcine gelatin, non-halal gelatin.