bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface coverage characterization of tinplates after post‐treatment processes
Authors: Wu F.J. , Liu X.J. , Xiao X. 
Published: August 2019

AbstractIn this paper, post‐treatments, including reflowing treatment, passivation treatment, and ultrasonic treatment for tinplates with different coating mass, are discussed, and surface characteristics brought by the post‐treatments have also been investigated by grazing incidence X‐ray diffraction and X‐ray photoelectron spectroscopy. Grazing incidence X‐ray diffraction results show the amount of highest iron and FeSn2 and lowest tin on tinplate with a coating mass of 1.1 g ⋅ m−2, indicating the poor surface coverage of steel substrate. The amount of lowest iron and tin‐iron alloy and highest tin on tinplate with a coating mass of 11.2 g ⋅ m−2 indicates the best surface coverage of tinplate among the four test samples. X‐ray photoelectron spectroscopy depth analysis shows that the sample with coating mass of 1.1 g ⋅ m−2 has a higher amount of iron atomic concentration, which decreases sharply as the coating mass increases, indicating the poor surface coverage by lower coating mass.
Radiotherapy after immunochemotherapy improves outcomes in patients with primary mediastinal large B‐cell lymphoma
Authors: Avilés Agustin , Calva Angel , Neri Natividad , Cleto Sergio , Silva Luis 
Published: August 2019

AbstractObjectivePrimary mediastinal B‐cell lymphoma is a rare and unique type of non‐Hodgkin's lymphoma that develops more frequently in younger patients and women. The combination of immunochemotherapy and radiotherapy (RT) has been suggested as the primary treatment choice. However, no consensus has been reached. Thus, we carried out an open‐label clinical trial. Patients with complete response after six cycles of immunochemotherapy were randomized to receive or not receive RT (control group).MethodsFrom July 2004 to December 2012, 324 patients with primary mediastinal B‐cell lymphoma were enrolled and randomized at 1:1, with 164 and 160 patients in the RT and control groups, respectively.ResultsThe 5‐year progression‐free survival was 84% (95% confidence interval [CI] 77–89%) in the RT group and 67% (95% CI 60–76%) in the control group (P < 0.01). The 5‐year overall survival was 86% (95% CI 79–96%) in the RT group and 68% (95% CI 60%–74%) in the control group (P < 0.01). Toxicity was minimal and well controlled. No late toxicities were observed.ConclusionRT as adjuvant treatment in patients with complete response after six cycles of immunochemotherapy improved the progression‐free survival and overall survival with minimal toxicities.
Highly Active Core–Shell Carbon/NiCo2O4 Double Microtubes for Efficient Oxygen Evolution Reaction: Ultralow Overpotential and Superior Cycling Stability
Authors: Zhang Xiaofeng , Li Xiaocui , Li Ruchun , Lu Yang , Song Shuqin , Wang Yi 
Published: August 2019

AbstractDeveloping highly efficient electrocatalysts with earth abundant elements for oxygen evolution reaction (OER) is a promising way to store light or electrical energy in the form of chemical energy. Here, a new type of electrocatalyst with core–shell carbon/NiCo2O4 double microtubes architecture is successfully synthesized through a hydrothermal method combined with the calcination process with wet tissues as the template and carbon resource. The outer NiCo2O4 nanosheet arrays contain abundant defects, which come from reduction of the carbon in wet tissues. This indicates that carbon is a very excellent defect inducer. The inner carbon microtubes can act as the robust structure skeleton and these core–shell double microtubes provide abundant diffusion channels for oxygen and electrolyte, both of which contribute to improving the stability by avoiding damage to the electrode from produced O2 bubbles and the collapse of the outer NiCo2O4 microtubes. Electrochemical results show that the electrode, core–shell carbon/NiCo2O4 double microtubes loaded on carbon cloth, exhibits prominent electrocatalytic activity with an overpotential of only 168 mV at 10 mA cm−2 and a Tafel slope as low as 57.6 mV dec−1 in 1.0 mol L−1 KOH. This new type of electrocatalyst possesses great potential in water electrolyzers and rechargeable metal–air batteries.
Zwitterionic PMCP‐Modified Polycaprolactone Surface for Tissue Engineering: Antifouling, Cell Adhesion Promotion, and Osteogenic Differentiation Properties
Authors: Chen Xingyu , Lin Zaifu , Feng Ying , Tan Hong , Xu Xinyuan , Luo Jun , Li Jianshu 
Published: August 2019

AbstractBiodegradable polycaprolactone (PCL) has been widely applied as a scaffold material in tissue engineering. However, the PCL surface is hydrophobic and adsorbs nonspecific proteins. Some traditional antifouling modifications using hydrophilic moieties have been successful but inhibit cell adhesion, which is not ideal for tissue engineering. The PCL surface is modified with bioinspired zwitterionic poly[2‐(methacryloyloxy)ethyl choline phosphate] (PMCP) via surface‐initiated atom transfer radical polymerization to improve cell adhesion through the unique interaction between choline phosphate (CP, on PMCP) and phosphate choline (PC, on cell membranes). The hydrophilicity of the PCL surface is significantly enhanced after surface modification. The PCL‐PMCP surface reduces nonspecific protein adsorption (e.g., up to 91.7% for bovine serum albumin) due to the zwitterionic property of PMCP. The adhesion and proliferation of bone marrow mesenchymal stem cells on the modified surface is remarkably improved, and osteogenic differentiation signs are detected, even without adding any osteogenesis‐inducing supplements. Moreover, the PCL‐PMCP films are more stable at the early stage of degradation. Therefore, the PMCP‐functionalized PCL surface promotes cell adhesion and osteogenic differentiation, with an antifouling background, and exhibits great potential in tissue engineering.
Gifted Children with ADHD: How Are They Different from Non-gifted Children with ADHD?
Authors: Gomez Rapson , Stavropoulos Vasileios , Vance Alasdair , Griffiths Mark D. 
Published: August 2019

AbstractThe present study focused on inattention and hyperactivity/impulsivity differences of gifted children with and without attention deficit-hyperactivity disorder (ADHD). Based on clinical assessment utilizing the Anxiety Disorders Interview Schedule for Children (ADISC-IV) and the Wechsler Intelligence Scale for Children—Fourth Edition, attendees of a public outpatient child service (boys = 359, girls = 148), with mean age 10.60 years (SD = 3.08 years), were allocated into four groups: ADHD (N = 350), gifted (N = 15), gifted/ADHD (N = 18), and clinical controls (N = 124). The Strengths and Weaknesses of ADHD-Symptoms and Normal Behavior Scale dimensionally assessed inattention and hyperactivity/impulsivity variations. Compared to the gifted/ADHD group, the ADHD group had higher scores for inattention and comparable scores for hyperactivity/impulsivity. For most symptoms, the ADHD groups (gifted or not) rated higher than the non-ADHD groups (control and gifted without ADHD). Findings appeared to indicate that (i) ADHD is a valid diagnosis among children who are gifted, (ii) gifted children might tend to be less inattentive than non-gifted ADHD children, and (iii) ADHD-gifted children appear to differ from the non-ADHD-gifted children with regard to specific hyperactive and impulsive behaviors. The practical implication of these findings is that clinicians may wish to focus on these symptoms when diagnosing ADHD among children with high intelligence.
Challenges in the management of data on extractive waste—the Polish case
Authors: Kulczycka Joanna , Dziobek Ewa , Szmiłyk Anita 
Published: August 2019

Abstract
The study analysed the waste statistics of European Union (EU) countries with particular emphasis on waste from extractive industries. Assessment of the data available at EU level (Eurostat) and presented by individual countries showed that even with a number of EU regulations and guidance, there are no complete, consistent and integrated reports that monitor the implementation of measures and support for waste management. Based on the example of Poland, a detailed analysis of the environmental reports from each mining company (to the regional database) and a grouping of the data according to EU waste codes were conducted for the 2017 data. The results were then compared with the data provided by the Central Statistical Office. It has been shown that there is a need for the reporting to be improved in order to avoid inconsistencies and to be able to undertake a detailed assessment of the approach and activities carried out with regard to their impact on the environment and society. Based on the example of Poland, the collection of data based on the waste code at the level of each mining company can be recommended, and this should be made available to the public by individual group of wastes on one platform (e.g. Eurostat) which would be helpful for proper waste management and the creation of industrial symbiosis and a quicker transformation towards a circular economy.
Value Creation in Art Galleries: A Service Logic Analysis
Authors: Williams Martin , Biggemann Sergio , Tóth Zsófia 
Published: August 2019

This study addresses how non-profit organisations like art galleries participate in co-creating value to visitors (customers), providers, and other stakeholders, and how these processes can be conceptualised within a service logic framework. We evaluate how an art gallery touring exhibition in regional Australia contributed to customer value, drawing on data collected in 2014–2016 from publications and websites, and interviews with staff of art galleries and arts organisations. Our findings illuminated four forms of value creation: financial, knowledge sharing, social and cultural, and professional value. Country art galleries have strong visitor orientation and employ co-creation processes focused on enhancing visitors’ experience, aligned with government directions on Indigenous understanding and objectives of local Indigenous art communities. However, customer value exchange is not well understood. The lack of marketing research expertise and usable visitor data is a barrier to value creation.
Examining differences in school hour and school day dietary quality among Canadian children between 2004 and 2015
Authors: Tugault-Lafleur Claire N , Barr Susan I , Black Jennifer L 
Published: August 2019

AbstractObjective:The present study aimed to: (i) evaluate changes in Canadian children’s dietary quality during school hours and on school days between 2004 and 2015; and (ii) explore whether changes in dietary quality over time were moderated by sociodemographic characteristics.Design:Nationally representative 24 h dietary recall data were obtained from the 2004 (n 4827) and 2015 (n 2447) Canadian Community Health Surveys. Dietary quality was measured using the Canadian Healthy Eating Index (C-HEI) which evaluates respondents’ compliance with 2007 national dietary recommendations, and the school-HEI which assesses respondents’ dietary quality during school hours. Multivariable regression models compared differences in dietary quality between 2004 and 2015. Interaction effects were used to test whether changes over time were moderated by sociodemographic characteristics (sex, age group, ethnicity, residential location, province of residence, parental education, food security status).Setting:Canada.Participants:Children aged 6–17 years.Results:Mean school-HEI score rose from 51.3 to 58.0 points (maximum = 100) from 2004 to 2015 (P < 0.001). School-HEI sub-scores for total vegetables and fruit, whole fruit, dark green and orange vegetables, milk and alternatives, and meat and alternatives improved over time, but remained well below recommendations. Decreased energy from minimally nutritious foods accounted for 39 % of the improvement in mean school-HEI scores. Mean whole day C-HEI scores also improved (60.8 to 66.4 points, P < 0.001). There was no evidence of a moderating effect for any of the sociodemographic variables examined.Conclusions:Mean dietary quality of Canadian children during school hours and on school days improved modestly for all age and sex groups but remained below 2007 national dietary recommendations.
Pyrolysis-induced shrinking of three-dimensional structures fabricated by two-photon polymerization: experiment and theoretical model
Authors: Cardenas-Benitez Braulio , Eschenbaum Carsten , Mager Dario , Korvink Jan G. , Madou Marc J. , Lemmer Uli , Leon Israel De , Martinez-Chapa Sergio O. 
Published: August 2019

AbstractThe introduction of two-photon polymerization (TPP) into the area of Carbon Micro Electromechanical Systems (C-MEMS) has enabled the fabrication of three-dimensional glassy carbon nanostructures with geometries previously unattainable through conventional UV lithography. Pyrolysis of TPP structures conveys a characteristic reduction of feature size—one that should be properly estimated in order to produce carbon microdevices with accuracy. In this work, we studied the volumetric shrinkage of TPP-derived microwires upon pyrolysis at 900 °C. Through this process, photoresist microwires thermally decompose and shrink by as much as 75%, resulting in glassy carbon nanowires with linewidths between 300 and 550 nm. Even after the thermal decomposition induced by the pyrolysis step, the linewidth of the carbon nanowires was found to be dependent on the TPP exposure parameters. We have also found that the thermal stress induced during the pyrolysis step not only results in axial elongation of the nanowires, but also in buckling in the case of slender carbon nanowires (for aspect ratios greater than 30). Furthermore, we show that the calculated residual mass fraction that remains after pyrolysis depends on the characteristic dimensions of the photoresist microwires, a trend that is consistent with several works found in the literature. This phenomenon is explained through a semi-empirical model that estimates the feature size of the carbon structures, serving as a simple guideline for shrinkage evaluation in other designs.
Genetic Contribution of Synthetic Hexaploid Wheat to CIMMYT’s Spring Bread Wheat Breeding Germplasm
Authors: Rosyara Umesh , Kishii Masahiro , Payne Thomas , Sansaloni Carolina Paola , Singh Ravi Prakash , Braun Hans-Joachim , Dreisigacker Susanne 
Published: August 2019

AbstractSynthetic hexaploid (SH) wheat (AABBD’D’) is developed by artificially generating a fertile hybrid between tetraploid durum wheat (Triticum turgidum, AABB) and diploid wild goat grass (Aegilops tauschii, D’D’). Over three decades, the International Maize and Wheat Improvement Center (CIMMYT) has developed and utilized SH wheat to bridge gene transfer from Ae. tauschii and durum wheat to hexaploid bread wheat. This is a unique example of success utilizing wild relatives in mainstream breeding at large scale worldwide. Our study aimed to determine the genetic contribution of SH wheat to CIMMYT’s global spring bread wheat breeding program. We estimated the theoretical and empirical contribution of D’ to synthetic derivative lines using the ancestral pedigree and marker information using over 1,600 advanced lines and their parents. The average marker-estimated D’ contribution was 17.5% with difference in genome segments suggesting application of differential selection pressure. The pedigree-based contribution was correlated with marker-based estimates without providing chromosome segment specific variation. Results from international yield trials showed that 20% of the lines were synthetic derived with an average D’ contribution of 15.6%. Our results underline the importance of SH wheat in maintaining and enhancing genetic diversity and genetic gain over years and is important for development of a more targeted introgression strategy. The study provides retrospective view into development and utilization of SH in the CIMMYT Global Wheat Program.
Effect of Protease Inhibitors in Healing of the Vaginal Wall
Authors: Florian-Rodriguez Maria , Chin Kathleen , Hamner Jennifer , Acevedo Jesus , Keller Patrick , Word R. Ann 
Published: August 2019

AbstractImpaired elastogenesis and increased degradation of elastic fibers has been implicated in the pathogenesis of pelvic organ prolapse. Loss of the elastogenic organizer, fibulin-5 (FBLN5), leads to pelvic organ prolapse in mice. The objective of this study was to investigate the regulation of FBLN5 after surgical injury of the vaginal wall using the rat as a preclinical animal model. Both endogenous and recombinant FBLN5 were degraded after surgical injury. Estrogen did not alter the dramatic loss of vaginal FBLN5 in the acute phase after injury (12–48 h), but resulted in rescue of the poor recovery of FBLN5 levels in the late phase (7 d) of healing in ovariectomized animals. In contrast with estrogen, the general MMP inhibitor, actinonin, abrogated injury-induced degradation of FBLN5 significantly. Further, actinonin rescued the negative effects of injury on biomechanics, histomorphology, and elastic fibers. Control of excessive matrix degradation by local application of actinonin at the time of surgery may lead to improved elastic fiber regeneration and wound healing, thereby potentially enhancing pelvic floor recovery after reconstructive surgery for prolapse.
Gold(I/III)-Phosphine Complexes as Potent Antiproliferative Agents
Authors: Kim Jong Hyun , Reeder Evan , Parkin Sean , Awuah Samuel G. 
Published: August 2019

AbstractThe reaction of gold reagents [HAuCl4•3H2O], [AuCl(tht)], or cyclometalated gold(III) precursor, [C^NAuCl2] with chiral ((R,R)-(-)-2,3-bis(t-butylmethylphosphino) quinoxaline) and non-chiral phosphine (1,2-Bis(diphenylphosphino)ethane, dppe) ligands lead to distorted Au(I), (1,2,4,5) and novel cyclometalated Au(III) complexes (3,6). These gold compounds were characterized by multinuclear NMR, microanalysis, mass spectrometry, and X-ray crystallography. The inherent electrochemical properties of the gold complexes were also studied by cyclic voltammetry and theoretical insight of the complexes was gained by density functional theory and TD-DFT calculations. The complexes effectively kill cancer cells with IC50in the range of ~0.10–2.53 μΜ across K562, H460, and OVCAR8 cell lines. In addition, the retinal pigment epithelial cell line, RPE-Neo was used as a healthy cell line for comparison. Differential cellular uptake in cancer cells was observed for the compounds by measuring the intracellular accumulation of gold using ICP-OES. Furthermore, the compounds trigger early – late stage apoptosis through potential disruption of redox homeostasis. Complexes1and3induce predominant G1 cell cycle arrest. Results presented in this report suggest that stable gold-phosphine complexes with variable oxidation states hold promise in anticancer drug discovery and need further development.
Near-future ocean acidification does not alter the lipid content and fatty acid composition of adult Antarctic krill
Authors: Ericson Jessica A. , Hellessey Nicole , Kawaguchi So , Nichols Peter D. , Nicol Stephen , Hoem Nils , Virtue Patti 
Published: August 2019

AbstractEuphausia superba (Antarctic krill) is a keystone species in the Southern Ocean, but little is known about how it will respond to climate change. Ocean acidification, caused by sequestration of carbon dioxide into ocean surface waters (pCO2), alters the lipid biochemistry of some organisms. This can have cascading effects up the food chain. In a year-long laboratory experiment adult krill were exposed to ambient seawater pCO2 levels (400 μatm), elevated pCO2 levels mimicking near-future ocean acidification (1000, 1500 and 2000 μatm) and an extreme pCO2 level (4000 μatm). Total lipid mass (mg g−1 DM) of krill was unaffected by near-future pCO2. Fatty acid composition (%) and fatty acid ratios associated with immune responses and cell membrane fluidity were also unaffected by near-future pCO2, apart from an increase in 18:3n-3/18:2n-6 ratios in krill in 1500 μatm pCO2 in winter and spring. Extreme pCO2 had no effect on krill lipid biochemistry during summer. During winter and spring, krill in extreme pCO2 had elevated levels of 18:2n-6 (up to 1.2% increase), 20:4n-6 (up to 0.8% increase), lower 18:3n-3/18:2n-6 and 20:5n-3/20:4n-6 ratios, and showed evidence of increased membrane fluidity (up to three-fold increase in phospholipid/sterol ratios). These results indicate that the lipid biochemistry of adult krill is robust to near-future ocean acidification.
Combining ZooMS and zooarchaeology to study Late Pleistocene hominin behaviour at Fumane (Italy)
Authors: Sinet-Mathiot Virginie , Smith Geoff M. , Romandini Matteo , Wilcke Arndt , Peresani Marco , Hublin Jean-Jacques , Welker Frido 
Published: August 2019

AbstractCollagen type I fingerprinting (ZooMS) has recently been used to provide either palaeoenvironmental data or to identify additional hominin specimens in Pleistocene contexts, where faunal assemblages are normally highly fragmented. However, its potential to elucidate hominin subsistence behaviour has been unexplored. Here, ZooMS and zooarchaeology have been employed in a complementary approach to investigate bone assemblages from Final Mousterian and Uluzzian contexts at Fumane cave (Italy). Both approaches produced analogous species composition, but differ significantly in species abundance, particularly highlighted by a six fold-increase in the quantity of Bos/Bison remains in the molecularly identified component. Traditional zooarchaeological methods would therefore underestimate the proportion of Bos/Bison in these levels to a considerable extent. We suggest that this difference is potentially due to percussion-based carcass fragmentation of large Bos/Bison bone diaphyses. Finally, our data demonstrates high variability in species assignment to body size classes based on bone cortical thickness and fragment size. Thus, combining biomolecular and traditional zooarchaeological methods allows us to refine our understanding of bone assemblage composition associated with hominin occupation at Fumane.
Simultaneous Proton Transfer Reaction-Mass Spectrometry and electronic nose study of the volatile compounds released by Plasmodium falciparum infected red blood cells in vitro
Authors: Capuano Rosamaria , Khomenko Iuliia , Grasso Felicia , Messina Valeria , Olivieri Anna , Cappellin Luca , Paolesse Roberto , Catini Alexandro , Ponzi Marta , Biasioli Franco , Di Natale Corrado 
Published: August 2019

AbstractThe discovery that Volatile Organic Compounds (VOCs) can be biomarkers for several diseases has led to the conception of their possible application as diagnostic tools. In this study, we aimed at defining of diagnostic signatures for the presence of malaria transmissible stages in infected individuals. To do this, we compared VOCs released by asexual and sexual stage cultures of Plasmodium falciparum, the deadliest species of malaria, with those emitted by uninfected red blood cells (RBCs). VOC analysis was carried out with an innovative set-up, where each sample was simultaneously analysed by proton transfer reaction time of flight mass spectrometry (PTR-ToF-MS) and an electronic nose. PTR-Tof-MS results show that sexual stages are characterized by a larger emission of hexanal, compared with uninfected or asexual stage-infected RBCs, which makes them clearly identifiable. PTR-Tof-MS analysis also detected differences in VOC composition between asexual stages and uninfected RBCs. These results have been substantially replicated by the electronic nose analysis and may open the possibility to develop sensitive and easy-to-use devices able to detect sexual parasite stages in infected individuals. This study also demonstrates that the combination of mass spectrometry with electronic noses is a useful tool to identify markers of diseases and to support the development of optimized sensors.