bluuebunny/crossref_metadata_2025_split huggingface dataset:
Soluble myeloid triggering receptor expressed on myeloid cell 1 might have more diagnostic value for bacterial ascites than C-reactive protein
Authors: Guo Qiang , Xu Chuanqin , Sun Chao , Zhao Yubao , Zhang Weifu 
Published: December 2018

AbstractThe timely and accurate diagnosis of ascites is of great significance for early treatment and prognostication. This study explored the value of soluble myeloid triggering receptor expressed on myeloid cell 1 (sTREM-1) and C-reactive protein (CRP) for assessing ascites. A total of 133 patients with ascites who received treatment at the Affiliated Hospital of Taishan Medical University between September 2015 and September 2017 were retrospectively analyzed. The ascites in 22, 45, 33 and 33 patients were tuberculous, bacterial, tumorous, and transudative, respectively. Healthy volunteers (n=30) who received a health examination at the same hospital during the same period constituted the control group. Before treatment, both ascitic sTREM-1 and CRP showed significant differences among the ascites subgroups (P<0.001), with the highest levels in the bacterial subgroup. Serum sTREM-1 and CRP also showed significant differences among the groups. A correlation analysis showed a positive correlation between sTREM-1 and CRP. ROC curves of the bacterial subgroup showed that when the optimal cutoff point was set to 20.2, the sensitivity, specificity, positive predictive value, and negative predictive value of the serum sTREM-1 index were 0.933, 0.955, 0.914, and 0.965, respectively. sTREM-1 may provide more diagnostic value than CRP for the diagnosis of bacterial ascites.
Characterization of Recycled Silk Fiber PP Composites with Optimal Performance of Silk Fibers by Response Surface Methodology
Authors: Rajkumar G. , Srinivasan J. 
Published: December 2018

Abstract
This article emphasizes the optimization of the retrieval of silk fibers from silk selvedge waste in a hard waste opening machine. It also highlights the characterization of composites developed from retrieved silk fibers with a polypropylene matrix in a compression molding machine. The machine conditions of the hard waste opener, such as the licker-in speed, cylinder speed, and setting between feed roller to licker-in, were optimized with respect to the fiber staple length using the Box-Behnken experimental design with response surface methodology. The optimum conditions for the fiber staple length were found to be licker-in speed, 550 r/min; cylinder speed, 280 r/min; and setting between feed roller to licker-in, 0.01 inch. Composites were developed using the silk fibers retrived at optimum conditions with polypropylene resin in compression molding at three different fiber loadings, namely 40, 50, and 60 weight % of silk fibers. The influece of silk fiber loading on the mechanical and thermal properties of the composites were studied and compared to pure PP composite. It is observed from the results that the composite with 50 weight % of silk fiber loading has shown greater mechanical properties. Furthermore, the incorporation of silk fibers in the polypropylene matrix has shown an improvement in the mechanical properties of 71.6 %, 76.66 %, 69.73 %, 67.97 %, and 58.45 % for tensile strength, tensile modulus, flexural strength, flexural modulus, and impact strength, respectively, in the composites when compared to pure polypropylene composite. The Differential Scanning Calorimetry analysis has also shown an increase in the degradation temperature of 8°C in the silk fiber-reinforced composite.
Cutting Performance of Luffa Cylindrica Fiber–Reinforced Composite by Abrasive Water Jet
Authors: Kalusuraman G. , Thirumalai Kumaran S. , Siva I. , Anand Kumar S. 
Published: December 2018

Abstract
The work addresses the cutting performance of luffa cylindrica fiber–reinforced composite by abrasive water jet machining (AWJM). The composite (30, 40, and 50 wt. % fiber) is prepared using the compression molding technique. The extracted fiber morphology and the composite properties were analyzed, as per ASTM. The influence of machining parameters, such as jet pressure (P), traverse speed (TS), and standoff distance (SoD) over the taper angle (TA) and surface roughness (Ra), were analyzed. Based on the experimental results, it was observed that a higher value of P and lower TS and SoD resulted with minimum TA and Ra. The developed multilinear regression model confirms the goodness-of-fit at 95 % confidence interval. The optimum condition to set (P at 25 MPa, SoD at 1.1414 mm, and TS at 20 mm/min) for attaining minimum TA and Ra were determined by desirability analysis. Further, the analysis of variance (ANOVA) of TA depicted a contribution of 41.71 % by SoD, followed by TS and P by 27.33 % and 23.74 %, respectively. Similarly, the ANOVA of Ra resulted with a contribution of 16.72 % by P, 39.15 % by SoD, and 30.73 % by TS. Finally, the cut surface morphology of the composite was analyzed at optimum condition, and the results are revealed.
Cabrera Rodríguez, José Antonio. “El trasfondo psicologista en la teoría schopenhaueriana de la percepción.”
Authors: Villamil Harol 
Published: December 2018

Cabrera Rodríguez, José Antonio. “El trasfondo psicologista en la teoría schopenhaueriana de la percepción.” Estudios de Filosofía 52 (2015): 95-110.
405 nm and 450 nm photoinactivation of Saccharomyces cerevisiae
Authors: Hoenes K. , Hess M. , Vatter P. , Spellerberg B. , Hessling M. 
Published: December 2018

Photoinactivation of bacteria with visible light has been reported in numerous studies. Radiation around 405 nm is absorbed by endogenous porphyrins and generates reactive oxygen species that destroy bacteria from within. Blue light in the spectral range of 450–470 nm also exhibits an antibacterial effect, but it is weaker than 405 nm radiation, and the photosensitizers involved have not been clarified yet, even though flavins and porphyrins are possible candidates.
There are significantly fewer photoinactivation studies on fungi. To test if visible light can inactivate fungi and to elucidate the mechanisms involved, the model organism Saccharomyces cerevisiae (DSM no. 70449) was irradiated with violet (405 nm) and blue (450 nm) light. The mean irradiation doses required for a one log reduction of colony forming units for this strain were 182 J/cm2 and 526 J/cm2 for 405 nm and 450 nm irradiation, respectively.
To investigate the cell damaging mechanisms, trypan blue staining was performed. However, even strongly irradiated cultures hardly showed any stained S. cerevisiae cells, indicating an intact cell membrane and thus arguing against the previously suspected mechanism of cell membrane damage during photoinactivation with visible light at least for the investigated strain. The results are compatible with photoinactivated Saccharomyces cerevisiae cells being in a viable but nonculturable state.
To identify potential fungal photosensitizers, the absorption and fluorescence of Saccharomyces cerevisiae cell lysates were determined. The spectral absorption and fluorescence results are in favor of protoporphyrin IX as the most important photosensitizer at 405 nm radiation. For 450 nm irradiation, riboflavin and other flavins may be the main photosensitizer candidates, since porphyrins do not play a prominent role at this wavelength. No evidence of the involvement of other photosensitizers was found in the spectral data of this strain.
Luiz Gama e Leandro Gomes de Barros em Perspectiva Dialógica
Authors: Marques Francisco Cláudio Alves , Lima Gustavo Henrique Alves de 
Published: December 2018

Neste artigo pretendemos investigar as possíveis relações dialógicas intertextuais que os poemas satíricos de Luiz Gama (1830-1882) e Leandro Gomes de Barros (1865-1918) estabelecem entre si bem como com a tradição oral e escrita da sátira, na qual os textos de ambos se inscrevem. Devem ser levadas também em consideração as relações dialógicas polifônicas – ou embates de vozes – que os textos destes poetas estabelecem com os discursos instituidores de “verdades” sobre as sociedades das quais fazem parte. Neste segundo tópico pretendemos investigar, em alguns poemas selecionados, como cada poeta respondeu às demandas de seu tempo, sobretudo políticas e sociais, que lhes foram apresentadas.Palavras-Chave: Leandro Gomes de Barros. Luiz Gama. Sátira. Luiz Gama and Leandro Gomes de Barros in Dialogical PerspectiveABSTRACTIn this article we intend to investigate the possible intertextual dialogical relations that the satirical poems of Luiz Gama (1830-1882) and Leandro Gomes de Barros (1865-1918) establish with each other as well as with the oral and written tradition of satire, in which the texts of both are inscribed. The polyphonic dialogical relationships - or clashes of voices - that these poets’ texts establish with the discourses that institute "truths" about the societies of which they are part must also be taken into account. In this second topic we intend to investigate, in some selected poems, how each poet responded to the demands of his time, especially political and social, that were presented to them.Keywords: Leandro Gomes de Barros. Luiz Gama. Satire.Luiz Gama y Leandro Gomes de Barros en Perspectiva DialógicaRESUMENEn este artículo pretendemos investigar las posibles relaciones dialógicas intertextuales que los poemas satíricos de Luiz Gama (1830-1882) y Leandro Gomes de Barros (1865-1918) se establecen entre sí así como con la tradición oral y escrita de la sátira, a la cual los textos de ambos se inscriben. Se deben tomar también en consideración las relaciones dialógicas polifónicas – o embates de voces – que los textos de estos poetas establecen con los discursos institucionalizados sobre las sociedades de las cuales forman parte. En este segundo tema pretendemos investigar, en algunos poemas seleccionados, cómo cada poeta respondió a las demandas de su tiempo, sobre todo políticas y sociales, que les fueron presentadas.Palabras clave: Leandro Gomes de Barros. Luiz Gama. Sátira.
Avaliação da exposição ocupacional à vibração de motosserra: um estudo sobre a colheita florestal no Espírito Santo
Authors: Bermudes Wanderson Lyrio , Minette Luciano José 
Published: December 2018

As atividades florestais contabilizaram, no período de 2007 a 2012, no Brasil, em média, uma incidência de 30 acidentes para cada grupo de 1.000. Esta pesquisa tem como o objetivo principal demonstrar a intensidade do agente físico “vibração localizada”, originado da utilização de motosserra nas atividades de colheita florestal em área de fomento no Espírito Santo. As avaliações foram realizadas conforme preconiza a Norma de Higiene Ocupacional NHO 10 da Fundação Jorge Duprat e Figueiredo (Fundacentro), e seus resultados comparados com as Normas Regulamentadoras NR-09 e NR-15 Anexo 8, que estabelecem os limites máximos permitidos para uma exposição diária de oito horas. A exposição média de vibração foi, para acionamento, de 2,8 m.s-2 e de 4,4 m.s-2 para empunhadura. A aceleração de maior intensidade para uma jornada de oito horas foi de 6,87 m.s-2, superior ao limite de tolerância de 5,0 m.s-2. Sugere-se nesta pesquisa a adoção de medidas de controle para a redução do risco de vibração, haja vista que a intensidade média ultrapassou o nível de ação.
EVALUASI SISTEM PELAPORAN INSIDEN KESELAMATAN PASIEN DI RUMAH SAKIT
Authors: Tristantia Arfella Dara 
Published: December 2018

Background: Incident reporting systems are designed to obtain information about patient safety and used for organizational and individual learning.Aims: The objective is to evaluate the implementation of patient safety incident reporting system at a hospital of Surabaya.Method: This study was an observational descriptive research supported by qualitative data. This study used Health Metrics Network (HMN) model.Results: The results of the input evaluation show that there was a policy that regulates the incident report, but its implementation was still not appropriate with no direct funding. However, facilities were provided for reporting. There were socialization for employees who have different understanding and responsibility, organizational structure of the patient safety team, problem solving method which had not used PDSA (Plan, Do, Study, Action), and computerized technology.Conclusion: The process evaluation shows that the indicators were in line with the rules. The data sources were in accordance with the guidelines. Data collection, process, presentation, and analysis were in line with the theory. The output evaluation shows the submission of incident reports had not been timely. Moreover, the report was complete and suitable to the existing guidelines, and it had been used for decision-making. It is required for the hospital to revise the guidebook of incidence reporting and improve the human resource skill.Keywords: evaluation, incident, patient safety, reporting
Flood inundation forecasts using validation data generated with the assistance of computer vision
Authors: Bhola Punit Kumar , Nair Bhavana B. , Leandro Jorge , Rao Sethuraman N. , Disse Markus 
Published: December 2018

Abstract
Forecasting flood inundation in urban areas is challenging due to the lack of validation data. Recent developments have led to new genres of data sources, such as images and videos from smartphones and CCTV cameras. If the reference dimensions of objects, such as bridges or buildings, in images are known, the images can be used to estimate water levels using computer vision algorithms. Such algorithms employ deep learning and edge detection techniques to identify the water surface in an image, which can be used as additional validation data for forecasting inundation. In this study, a methodology is presented for flood inundation forecasting that integrates validation data generated with the assistance of computer vision. Six equifinal models are run simultaneously, one of which is selected for forecasting based on a goodness-of-fit (least error), estimated using the validation data. Collection and processing of images is done offline on a regular basis or following a flood event. The results show that the accuracy of inundation forecasting can be improved significantly using additional validation data.
Impact of upstream runoff and tidal level on the chlorinity of an estuary in a river network: a case study of Modaomen estuary in the Pearl River Delta, China
Authors: He Yanhu , Chen Sha , Huang Ruizhen , Chen Xiaohong , Cong Peitong 
Published: December 2018

Abstract
Saltwater intrusion exerts great impact on water supply and water withdrawal from estuarine areas. A chlorinity prediction model based on backpropagation neural network was constructed, calibrated, and validated, considering phase lags, with the Modaomen estuary in the Pearl River Delta (PRD), China as case study. This study aimed to investigate impacts of upstream runoff and tidal level on the changing properties of estuarine chlorinity. Nine boundary conditions – low tide and tidal range both with three different frequencies – were designed to explore the changing process of estuarine chlorinity and obtain the critical upstream runoff for saltwater suppression. Results indicated the model performed efficiently; Nash–Sutcliffe efficiency coefficient and R2 were both 0.91 in training period, 0.76 and 0.82 in testing period, and 0.64 and 0.77 in validation period, respectively, and estuarine chlorinity shows slightly different changing processes of decline rate under the nine boundary conditions when the upstream runoff increases. The higher the designed tidal range and lower daily tides together with the smaller the amount of upstream runoff, the higher the estuarine chlorinity. The critical upstream runoff of the Pinggang pumping station is 2,500 m3/s. These findings provide a foundation for water supply security and upstream reservoir dispatching in estuarine areas in dry periods.
Motivators for treated wastewater acceptance across developed and developing contexts
Authors: Rice Jacelyn , Stotts Rhian , Wutich Amber , White Dave , Maupin Jonathan , Brewis Alexandra 
Published: December 2018

Abstract
As water scarcity increases, we must turn to underutilized sources such as treated wastewater. While work has been done on barriers to public acceptance, less work has been undertaken to explore motivations that may incentivize adoption of this potential water source. Using data collected from respondents in four global sites (in Guatemala, Fiji, New Zealand, and Spain), we (1) analyzed how four motivators (cost, current and future water shortages, and ecological conservation) influenced respondents' willingness to use treated wastewater and (2) examined if respondents' willingness varied across contexts based on the level of wastewater treatment available. Despite a focus in previous research on the role of reducing cost and providing economic incentives for wastewater reuse adoption, cost was broadly the least motivating factor while ecological conservation and future water shortages were the two strongest motivators across all sites. Additionally, respondents in sites with low levels of wastewater technology were more likely to express a willingness to use treated wastewater given any motivator.
Mesoporous Silica Nanoparticles as a Prospective and Promising Approach for Drug Delivery and Biomedical Applications
Authors: Pu Xiaohui , Li Jia , Qiao Peng , Li Mengmeng , Wang Haiyan , Zong Lanlan , Yuan Qi , Duan Shaofeng 
Published: December 2018

Background:
With the development of nanotechnology, nanocarrier has widely been applied
in such fields as drug delivery, diagnostic and medical imaging and engineering in recent
years. Among all of the available nanocarriers, mesoporous silica nanoparticles (MSNs) have become
a hot issue because of their unique properties, such as large surface area and voidage, tunable
drug loading capacity and release kinetics, good biosafety and easily modified surface.

Objective:
We described the most recent progress in silica-assisted drug delivery and biomedical applications
according to different types of Cargo in order to allow researchers to quickly learn about
the advance in this field.

Methods:
Information has been collected from the recently published literature available mainly
through Title or Abstract search in SpringerLink and PubMed database. Special emphasis is on the
literature available during 2008-2017.

Results:
In this review, the major research advances of MSNs on the drug delivery and biomedical
applications were summarized. The significant advantages of MSNs have also been listed. It was
found that the several significant challenges need to be addressed and investigated to further advance
the applications of these structurally defined nanomaterials.

Conclusion:
Through approaching this review, the researchers can be aware of many new synthetic
methods, smart designs proposed in the recent year and remaining questions of MSNs at present.
Evaluation of Cytotoxic Potentials of Some Isoindole-1, 3-Dione Derivatives on HeLa, C6 and A549 Cancer Cell Lines
Authors: Tan Ayse , Yaglioglu Ayse Sahin , Kishali Nurhan Horasan , Sahin Ertan , Kara Yunus 
Published: December 2018

Objective:
Considering this information, firstly, isoindole derivatives containing different functional
groups 4-13 have been synthesized from 2-alkyl/aryl-3a, 4,7,7a-tetrahydro-1H-isoindole-1,
3(2H)-dione.

Background:
Norcantharimides are known as norcantharidine derivatives and contain
an isoindole skeleton structure. Isoindole derivatives have positive effect on inflammatory pathologies
including cancers.

Methods:
For the synthesis of all compounds, 2-alkyl/aryl-3a, 4,7,7a-tetrahydro-1H-isoindole-
1,3(2H)-dione was used as the starting compound. The syntheses were based on two main reactions:
Ene-reaction of singlet oxygen and epoxidation. Secondly, their anticancer activities were
evaluated against HeLa, C6 and A549 cancer cell lines by the BrdU assay.

Results:
Anticancer activities of synthesized compounds (4-13) and 5-FU (5-Florouracil) against
HeLa, C6 and A549 cells were investigated at four concentrations (100, 50, 25 and 5 μM). IC50
values of compounds 4-13 were calculated for all cancer cell lines. The investigated compounds
showed anticancer activity against the cancer cell lines depending on doses. Compound 7 containing
azide and silyl ether exhibited higher inhibitory activity than the other compounds and 5-FU
against A549 cancer cell lines (IC50 =19.41± 0.01 μM). Compounds 9 and 11 were determined to
exhibit cell-selective activity against HeLa cancer cell lines. Compound 11 had higher activity than
the positive control at 100 μM concentrations against C6 cancer cell lines.

Conclusion:
According to the results observed, isoindole derivatives 7, 9, and 11 might be good
potential anticancer agents for the treatment of cervical and glioma cancer due to their antiproliferative
properties, having less cytotoxic effects on healthy cells. In addition, compound 7 could be
used in in vivo studies of all three-cancer cell lines (C6, HeLa, and A549).
Melamine Detection in Food matrices employing Chicken Antibody (IgY): A Comparison between Colorimetric and Chemiluminescent Methods
Authors: Sushma Umesh , Srivastava Alok K. , Krishnan Manonmani H. 
Published: December 2018

Background:Melamine, contains 67% nitrogen by mass, and is adulterated in foods to uplift false protein. There is an urgent requirement to develop fast screening techniques for monitoring melamine in foods.Objective:To develop rapid, high throughput detection techniques for melamine in the food matrix.Methods:IgY antibodies were developed against melamine in the hen, isolated and used for detection of melamine. The detection by colorimetric and chemiluminescent methods was compared.Results:The detection range for melamine was 1 ng-25 µg by the colorimetric method and 10 fg/mL-25 ng/mL by the chemiluminescent method. There was a very low matrix effect, where the recovery was 86 to 106 % by colorimetric method and 71 to 98 % by the chemiluminescent method.Conclusion:Both colorimetric and chemiluminescent methods could be employed for the fast and consistent melamine detection in the food matrix.
Study of the Fragmentation Pathways of Sulfonamides by High-resolution Mass Spectrometry: Application to their Detection in Plasma by Direct Infusion
Authors: Kokotou Maroula G. 
Published: December 2018

Background:
The high resolving and accuracy power of the HRMS instrument enabled us to
identify the product ions and to propose detailed fragmentation pathways and diagnostic fragment ions.

Methods:
In the present work, the fragmentation pathways of five sulfonamides antibiotics, namely
sulfamerazine, sulfathiazole, sulfadiazine, sulfadimethoxine and sulfamethoxazole, by High-Resolution
Mass Spectrometry (HRMS) are presented. The HRMS spectra were recorded with a Q-TOF (Time of
Flight) spectrometer with Electrospray Ionization (ESI) in both negative and positive mode.

Results:
Specific characteristic ions for each one of the sulfonamide antibiotics under positive ESI
mode are proposed for the first time. Fragment ions of this particular class of analytes may be used to
rapidly identify compounds with common structural features.

Conclusion:
The direct infusion of plasma samples, avoiding any prior chromatographic steps, to identify
the existence of sulfonamide antibiotics is demonstrated herein.