bluuebunny/crossref_metadata_2025_split huggingface dataset:
Processos e políticas de avaliação no Ceará: cooperação e responsabilização
Authors: Soares Erineuda do Amaral , Werle Flávia Obino Corrêa 
Published: May 2018

O presente estudo tem como objetivo analisar os revérberos da avaliação da educação nas últimas décadas no Brasil. Explicita o uso de premiação e incentivos financeiros propostos pelos estados a partir dos resultados dos alunos nessas avaliações. O exemplo apresentado é o Prêmio Escola Nota Dez no Ceará. Foi usada a revisão bibliográfica como metodologia, priorizando o enfoque comparado dos principais documentos legais que embasam as avaliações em larga escala tanto na esfera internacional, como nacional e estadual. Conclui-se que os resultados das avaliações em larga escala dos estados brasileiros influenciam as políticas públicas educacionais, principalmente nos repasses financeiros às escolas e municípios com maior e menores índices obtidos nas avaliações. As avaliações, nesse contexto, seguem a lógica da educação contábil e replicação das experiências exitosas por meio de uma cooperação técnico-pedagógica de transferência das práticas que deram ‘certo’ numa tentativa de qualificar, porém, também uniformizando o ensino. Palavras-chave: Avaliação. Políticas Educacionais. Cooperação.
Produção de vídeos amadores de experimentos: algumas contribuições para se pensar o processo educativo
Authors: Francisco Junior Wilmo Ernesto , Benigno Ana Paula Aquino 
Published: May 2018

A produção de vídeos de experimentos se descortina como uma ferramenta para as atividades experimentais, permitindo entrelaçar experimento, linguagem audiovisual e a ciência química. Nesses termos, o presente trabalho investigou a produção de vídeos de experimentos por estudantes, focando especialmente as questões técnico-estéticos da produção e como estas podem se interrelacionar com o processo educativo. A análise dos vídeos demonstrou a presença espontânea de técnicas e elementos estéticos (música, dramatização, humor) que muitas vezes não se fazem presentes nas aulas de ciências. A diversão, a liberdade, a criatividade e a responsabilidade foram características que surgiram e estão ligadas ao caráter lúdico e ao engajamento pela atividade. Assim, a interação e o envolvimento dos sujeitos na produção dos vídeos possibilitam ao professor promover a discussão do conhecimento científico de maneira ampliada. Palavras-chave: Linguagem Audiovisual. Experimentação. Tecnologias Digitais.
Possible protective effect of curcumin on the thyroid gland changes induced by sodium fluoride in albino rats: light and electron microscopic study
Authors: Abdelaleem Mohamed Mostafa , El-Tahawy Nashwa Fathy Gamal , Abozaid Samah Mohammed Mahmoud , Abdel-Hakim Shima Abdel-Baset 
Published: May 2018

Abstract

Objectives. Thyroid gland regulates the body’s metabolic rate and plays an exquisitely important role in the human health. Fluoride exposure can affect thyroid function. Curcumin is a potent antioxidant that works through several mechanisms. The aim of the present study was to demonstrate the hormonal, histological, and ultrastructural changes occurred in the thyroid gland induced by exposure to sodium fluoride (NaF) and study the possible protective effect of curcumin on the NaF-induced effects.

Methods. Thirty male albino rats were randomly divided into 3 equal groups (10 rats each): the control group, NaF group, and NaF+Curcumin (NaF+Cur) group. Thyroid-stimulating hormone (TSH), triiodothyronine (T3) and thyroxine (T4) levels were assayed and thyroid tissues processed for light and transmission electron microscopic study.

Results. In NaF group, serum T3 and T4 levels were significantly decreased whereas TSH level was significantly increased compared to the control group. Thyroid tissues showed flattening of the epithelial lining with several follicular cell degenerations, hyperplasia, decreased colloid, disrupted basement membrane, cytoplasmic vacuolations, degenerated mitochondria, widening of rough endoplasmic reticulum cisternae, and vascular congestion compared to the control group. In the NaF+Cur group, serum TSH levels were significantly decreased in comparison with NaF group and no significant difference in comparison with the control group. Thyroid sections appeared apparently normal compared to the control group and NaF group.

Conclusions. Sodium fluoride affected both the function and structure of the thyroid gland while curcumin was protective against these toxic effects.
Darapladib inhibits atherosclerosis development in type 2 diabetes mellitus Sprague-Dawley rat model
Authors: Wihastuti Titin Andri , Heriansyah Teuku , Hanifa Hanifa , Andarini Sri , Sholichah Zuhrotus , Sulfia Yuni Hendrati , Adam Aditya Angela , Refialdinata Jeki , Lutfiana Nurul Cholifah 
Published: May 2018

Abstract

Objective. Increase in the low-density lipoprotein (LDL) level in diabetes mellitus and atherosclerosis is related to lipoprotein associated phospholipase A2 (Lp-PLA2). Lp-PLA2 is an enzyme that produces lysophosphatidylcholine (LysoPC) and oxidized nonesterified fatty acids (oxNEFA). LysoPC regulates inflammation mediators, including intra-cellular adhesion molecule-1 (ICAM-1). Darapladib is known as a Lp-PLA2 specific inhibitor. The aim of this study was to reveal the effect of darapladib on the foam cell number, inducible nitric oxide synthase (iNOS), and ICAM-1 expression in aorta at early stages of the atherosclerosis in type 2 diabetes mellitus Sprague-Dawley rat model.

Methods. Thirty Sprague-Dawley male rats were divided into 3 main groups: control, rats with type 2 diabetes mellitus (T2DM), and T2DM rats treated with darapladib (T2DM-DP). Each group was divided into 2 subgroups according the time of treatment: 8-week and 16-week treatment group. Fasting blood glucose, insulin resistance, and lipid profile were measured and analyzed to ensure T2DM model. The foam cells number were detected using hematoxylin-eosin (HE) staining and the expression of iNOS and ICAM-1 was analyzed using double immunofluorescence staining.

Results. Induction of T2DM in male Sprague-Dawley rats after high fat diet and streptozotocin injection was confirmed by elevated levels of total cholesterol and LDL and increased fasting glucose and insulin levels compared to controls after both times of treatment. Moreover, T2DM in rats induced a significant increase (p<0.05) in the foam cells number and iNOS and ICAM-1 expression in aorta compared to controls after both treatment times. Darapladib treatment significantly reduced (p<0.05) foam cells number as well as iNOS expression in aorta in rats with T2DM after both treatment times. A significant decrease (p<0.05) in ICAM-1 expression in aorta was observed after darapladib treatment in rats with T2DM only after 8 weeks of treatment.

Conclusion. Our data indicate that darapladib can decrease the foam cells number, iNOS, and ICAM-1 expression in aorta at the early stages of atherosclerosis in T2DM rat model.
Glucometabolic effects of single and repeated exposure to forced-swimming stressor in Sprague-Dawley rats
Authors: Morakinyo Ayodele Olufemi , Iranloye Bolanle Olubusola , Ogunsola Oluseyi Abimbola 
Published: May 2018

Abstract

Objectives. We aimed to evaluate the effects of a single (acute) and repeated (chronic) exposure to forced-swimming stressor on glucose tolerance, insulin sensitivity, lipid profile and glycogen content in male rats.

Methods. Thirty adult male Sprague-Dawley rats (12 weeks old) were divided randomly into five groups: control group, single exposure (SE) to forced-swim stressor, repeated exposure to forced-swim stressor for 7 days (RE7), 14 days (RE14) and 28 days (RE28). Glucose tolerance test and Homeostatic Model Assessment-Insulin Resistance (HOMA-IR) were undertaken on fasting rats to obtain glucose and insulin profiles. ELISA was performed to assess plasma insulin and corticosterone levels. Total cholesterol, triglyceride, high- and low-density lipoproteins, hepatic and skeletal glycogen content were also determined.

Results. Repeated exposure to stressor induced glucose intolerance and insulin resistance in the experimental rats. Results showed that all RE groups exhibited a significantly higher area under the curve compared with others (p=0.0001); similarly, HOMA-IR increased (p=0.0001) in all RE groups compared with control. Prolonged exposure to stressor significantly increased the plasma insulin and corticosterone levels but decreased the glycogen content in the liver and skeletal muscle when compared with the control group. Additionally, chronic stressor significantly increased the total cholesterol and triglyceride levels, however, acute stressor produced significantly elevated high-density lipoproteins level.

Conclusions. In conclusion, repeated exposure to forced-swimming stressor induced glucose intolerance and insulin resistance in rats by disrupting the insulin sensitivity as well as heightening the glycogenolysis in the liver and skeletal muscle. Acute stressor was unable to cause glucose intolerance and insulin resistance but it appears that may have a positive effect on the lipid metabolism.
Key Enabling Technologies – is the Czech Republic catching up the leading countries in innovation and technology?
Authors: Kučera Zdeněk , Vondrák Tomáš 
Published: May 2018

Abstract
The topic of this contribution is a comparison of the research & development related to the “key enabling technologies” (KETs) in the Czech Republic and the European Union as a whole with selected non-European economies. A further aim of this article is an appraisal of the effect of the European strategies and action programmes which have been implemented since the turn of the decade and which target the lagging of EU in innovations in critical technologies. We use the publication and the patent activities as a proxy to assess the intensity of the KETs oriented R&D. The Asian countries Japan, South Korea and the fast growing China have the highest fraction of KETs oriented publications and patents in their national output. The Chinese State Intellectual Property Office (SIPO) recorded in 2015 a half of the world patent applications related to KETs. Measured by their share of publications, the Asian countries exhibit a significantly more intensive R&D in the majority of KETs. Whereas the patent activity of the Asian countries grows the number of patent applications in the EU stagnates in the recent years and EU visibly lags behind the Asian competitors. The EU R&D policies and strategies aimed at the promotion of KET and the financial support does not seem exhibiting visible effects. In the Czech republic KETs became an organic component of the National Research and Innovation Strategy for the intelligent specialisation (National RIS3 strategy) and a number of targeted public financing programmes support KETs related projects. The situation in the Czech Republic has been evolving in a positive way between 2008 and 2016. Both the number of publications and patent applications related to KETs has been increasing and the growth dynamics approaches the Asian countries. The number of publications per research worker in the Czech Republic is on par with the EU. Due to a stronger growth in recent years of the number of patent applications in comparison to EU the Czech republic reached the EU average per researcher and the fraction of the KETs related applications surpasses the EU average and even some developed countries.
Legal analysis of the new register of research organizations
Authors: Kobert Martin 
Published: May 2018

Abstract
In the middle of 2017 the Ministry of Education, Youth and Sports published a new register of research organizations as part of an ongoing effort to establish, within the framework of the Czech Republic state administration, a central body responsible for assessing the defining attributes of research organizations, thereby removing the need for each grantor to conduct such assessment individually. The consequence of this measure is to effectively replace the existing register maintained by the Research, Development and Innovation Council, which essentially has no legal relevance compared to this new register. Successful completion of the assessment is a requirement for research organizations to obtain funding not considered to be state aid therefore the existence of a legally binding register is crucial even though the above mentioned authorities do not perceive it this way. This approach questions the future of the register itself underscored by the fact that it has been marred by legislative errors. However, the register now works and more than 112 entities (updated to 14th of December 2017) are registered and available for grantors to use to assess beneficiaries. The aim of this article is presentation with its legal substance and analysis of its meaning for potential registrants, especially in the context of providing grants, including the relevant issues.
Participation connections between programmes supporting business research and follow-up additionality of participation in the programmes IMPULS, TANDEM and TIP
Authors: Kostić Miroslav 
Published: May 2018

Abstract
In the first part of the article, connections between the most substantial non-investment public programmes supporting business research are analysed, namely by the share of participants following with participation in subsequently launched programmes and their share on the total allocated support. The second part of the text deals with participation connections between earlier started programmes – IMPULS, TANDEM and TIP – and afterwards started programmes ALFA and CENTRA KOMPETENCE. Groups of beneficiaries divided according to their participation or non-participation in following programmes are compared on the basis of several structural features. According to data analysis, repeated participation in the programmes supporting business research is positively influenced by the size of supported companies. Publicly owned companies have higher tendencies to repeated participation in these programmes considering the fact that their main economic activity is more often research and development than in the case of private companies. In sectorial structure of beneficiaries with repeated participation in public programmes, especially R&D with related knowledge intensive services and certain high-tech & medium high-tech industries were more represented compared to the group of beneficiaries not participating in later started programmes. The third part of the article deals with the issue of follow-up additionality, here reduced to examining differences in behaviour of companies participating and non-participating in following programmes supporting business R&D. These differences viewed through two indicators – R&D expenditure from various resources and number of employees in R&D – were monitored in the years following the allocation of public support. Repeated participation in public programmes has an evident connection with the inflow of business R&D funding from other businesses. This source of funding enabled beneficiaries participating in a follow-up support programme – despite the constant reduction of public funding – to increase or at least slow down the decrease of total R&D funding. Trend of decreasing R&D expenditure and R&D employment, obvious mainly in the group of beneficiaries with no follow-up participation, apparently relates to the reduction of public expenditures on business research and thus indicates reliance of beneficiaries on the public support of R&D.
Modelling Morphographemic Alternations in Derivation of Czech
Authors: Ševčíková Magda 
Published: May 2018

Abstract
The present paper deals with morphographemic alternations in Czech derivation with regard to the build-up of a large-coverage lexical resource specialized in derivational morphology of contemporary Czech (DeriNet database). After a summary of available descriptions in the Czech linguistic literature and Natural Language Processing, an extensive list of alternations is provided in the first part of the paper with a focus on their manifestation in writing. Due to the significant frequency and limited predictability of alternations in Czech derivation, several bottom-up methods were used in order to adequately model the alternations in DeriNet. Suffix-substitution rules proved to be efficient for alternations in the final position of the stem, whereas a specialized approach of extracting alternations from inflectional paradigms was used for modelling alternations within the roots. Alternations connected with derivation of verbs were handled as a separate task. DeriNet data are expected to be helpful in developing a tool for morphemic segmentation and, once the segmentation is available, to become a reliable resource for data-based description of word formation including alternations in Czech.
The Miraculous Virgin: Journey from Novella to Shooting Script
Authors: Michalovič Michal 
Published: May 2018

Abstract
Dominik Tatarka’s novella The Miraculous Virgin was first published in 1944. Twenty years later a second edition (revised by the author) was published and at approximately the same time Tatarka wrote a literary script for an intended film based on his novella. Director Štefan Uher (who had previously directed three feature films – Class Nine A, The Sun in a Net and The Organ) undertook the film adaptation. He wrote the shooting script based on Tatarka’s literary script and in 1966 he directed the movie The Miraculous Virgin. In the present study the author analyses the evolution of the text from one version to another. Tatarka’s modifications to the text and Uher’s subsequent changes are being analysed. The readers – and future audience of the film – had at their disposal four literary versions of The Miraculous Virgin: two editions of the novella, a film treatment by Tatarka (published in two issues of the Slovenské pohľady magazine in 1964) and a so-called literary script (published in 1966). Therefore we can talk about a complex consisting of various components and we can analyse in detail the relationship between them.
Evaluating Traffic Risk Indexes in Iran’s Rural Roads. Case Study: Ardabil-Meshkin Rural Road
Authors: Sadeghpour Mazdak , Mohammadi Mehdi 
Published: May 2018

Abstract
The main objective of this study is to rank the chief parameters and their important features which lead to rural roads accidents in Iran. To conduct this, an item as Risk Index is defined as the risk of a parameter and feature causing road accidents. Of all detected parameters, only five parameters and their features were chosen. Then Analytic Hierarchy Process (AHP) was applied to find the scores of Risk Indexes of each parameter and feature to rank them with regard to the two main criteria. These criteria were “Effect on Accidents Number” and “Effect on Accident Severity”. The data of this research was collected from two forms of questionnaires. Each of the 622 participants of this research filled both forms of the questionnaires. The results show that considering only Risk Index of main parameters in rural roads led to a big misunderstanding about detecting traffic accident causes. A comparison between obtained scores for both Risk Indexes of parameters and features clarifies that paying more attention to road features rather than road parameters can bring about detecting hazardous locations more accurately to assign limited budget to vulnerable locations in rural roads and decrease the rate of traffic accidents.
Promising Directions for the Logistics Service Providers Development on the Russian Market in Times of Recession
Authors: Dybskaya Valentina V. , Vinogradov Andrey B. 
Published: May 2018

Abstract
The Russian market of logistics services suffered substantial losses during recent economic recession. Decrease in import from the EU and the USA, reduction of consumer spending within the country, increased borrowing costs led to sharp reduction in the growth rate of the investigated market value. Shortage of the modern infrastructure, fragmentation and imbalance of the Russian logistics market have contributed badly. This article focuses on identification of the promising strategic development directions for logistics service providers operating on the Russian market. On the basis of literature survey, the authors derive attractive client groups for 3PL operators, priority regions for geographical expansion as well as high-demand logistics and related services. The results of this survey could help logistics agents to define or clarify their market positioning and serve as a basis for further study of specific features in logistics outsourcing development in Russia.
New Data about Snail-Killing Flies (Diptera, Sciomyzidae) in Iran
Authors: Khaghaninia S. , Kazerani F. , Vala Jean-Claude 
Published: May 2018

Abstract
Based on material collected in East Azerbaijan Province during 2009-2012, 15 species belonging to 11 genera of the family Sciomyzidae are recorded. Two species, Euthycera sticticaria (Mayer, 1953) and Tetanocera arrogans Meigen, 1830, are recorded for the first time from Iran. Biology and distribution of all species are provided. Also a key to Coremacera Rondani, 1856 species in Middle East and central Asia is provided.
First Note on Fish Parasites in Polissky Nature Reserve, Northern Ukraine
Authors: Rubtsova N. Yu. , Kutsokon Yu. K. 
Published: May 2018

Abstract
Nineteen species of parasites belonging to seven taxonomical groups were detected in nine species of fish (Gobio gobio (Linnaeus, 1758), Cobitis taenia Linnaeus, 1758, Squalius cephalus (Linnaeus, 1758), Rutilus rutilus (Linnaeus, 1758), Misgurnus fossilis (Linnaeus, 1758), Sabanejewia baltica Witkowski, 1994, Barbatula barbatula (Linnaeus, 1758), Esox lucius Linnaeus, 1758 and Perca fluviatilis Linnaeus, 1758) from two small rivers in Polissky Nature Reserve in the northern part of Ukraine. Th e highest species richness of parasites was registered for G. gobio (7 species). Four species of parasites were found in S. cephalus. Three parasite species were found in E. lucius. Two parasite species were detected in R. rutilus and P. fluviatilis. C. taenia, M. fossilis, and S. baltica harboured each one species of parasites. Gyrodactylus sp. from S. baltica was reported for the first time. All parasites represent new geographical finding for the north of Ukraine.
Earthworms (Lumbricidae) as Intermediate Hosts of Lung Nematodes (Metastrongylidae) of Swine in Kyiv and Zhytomyr Regions of Ukraine
Authors: Antipov A. A. , Bakhur T. I. , Feshchenko D. V. , Romanishina T. A. , Avramenko N. V. , Goncharenko V. P. , Zghozinska O. A. , Solovyova L. M. , Koziy N. V. , Pidborska R. V. , Shahanenko V. S. , Dzhmil V. I. , Tyshkivska N. V. 
Published: May 2018

Abstract
The article presents the data on prevalence and intensity of earthworms’ infection with metastrongylid larvae in pork production enterprises of Kyiv and Zhytomyr Regions of Ukraine. In the investigated areas, six species of lumbricids were collected and identifi ed: Eisenia fetida (Savigny, 1826), Aporrectodea rosea (Savigny, 1826), A. caliginosa (Savigny, 1826), Dendrodrilus rubidus (Savigny, 1826), Lumbricus rubellus (Linnaeus, 1758), L. terrestris (Linnaeus, 1758). Th e studies were carried out from April to September, 2016, both in pig farms and on pastures. We observed no pronounced changes in prevalence and intensity of infection during the warm period of the year. Th e highest infection rates were detected in earthworms living under the wooden floor of pigpens and in its cracks. In the studied localities, metastrongylid larvae were found in the most common worms of the Lumbricidae family: E. foetida, D. rubidus, A. caliginosa, and L. rubellus.