bluuebunny/crossref_metadata_2025_split huggingface dataset:
Instruction for authors
Authors: Alsamarai Abdulghani 
Published: October 2018

Introduction

The International Journal of Medical Sciences [IJMS], ISSN 2522-7386, is a peer-reviewed, 3 issues published annually. Authors are invited to submit for publication articles with a wide spectrum of coverage reporting original work, in the fields of medicine, nursery, dentistry, and pharmacy sciences. Review articles are usually by invitation only. However, Review articles of current interest and high standard will be considered. Prospective work should not be back dated. There are also sections for Case Reports, Brief Communication, correspondence and medical news items. Authors should read the editorial policy and publication ethics before submitting their manuscripts. Authors should also use the appropriate reporting guidelines in preparing their manuscripts
Perancangan Program Pengelolaan Transaksi Pembelian dan Penjualan Perlengkapan Olahraga Pada Abadi Sport
Authors: Nurahman Dede , Prasetyo Feri , Pratama Eka 
Published: October 2018

Abstract – Purchasing and Sale of Goods System is a system that provides information services in the form of transaction data purchase and sale of goods and stock of goods. The existence of this information system is important. In this case, ABADI SPORT serve as a place of research, because the system of purchase and sale of goods in the place has not been well managed so that there is often a mistake in making the existing report, ineffective and efficient data storage because only archived. So as to complicate the search of data, the form of invoice is similar to causing an error in Recording, slow presentation of information required by the leadership. The method used is structured programming language and development method using waterfall model. Data collection method used is using observation method, interview, literature study. Analytical tools used are Use Case Diagram, Activity Diagram, Entity Relationship Diagram (ERD), Logical Record Structure (LRS). The software used is: NetBeans IDE 8.1, java 1.7.7, and Xampp 1.7.7. The design of this program is built in order to provide convenience in processing data purchase and sale both from purchases to suppliers and sales to customers as well as processing reports purchase and sales to be more precise and accurate. Key Word: Program Design, Purchasing and Sales Program
PENGENALAN POLA PADA FISIK MOBIL MENGGUNAKAN PERSAMAAN DIFERENSIAL DETEKSI TEPI (EDGE DETECTION)
Authors: Rada Yus Tina 
Published: October 2018

Penentuan tepi suatu objek dalam pengolahan citra merupakan salah satu wilayah pengolahan citra digital yang paling awal dan paling banyak diteliti. Proses ini sering kali ditempatkan sebagai langkah pertama dalam aplikasi segmentasi citra, yang bertujuan untuk mengenali objek-objek yang terdapat dalam citra ataupun konteks citra secara keseluruhan. Adapun teknik peningkatan mutu citra dapat dibagi menjadi dua, yaitu peningkatan mutu citra pada domain spasial dan domain frekuensi. Pada domain spasial terdapat dua macam jenis filter, yaitu Smoothing filters dan Sharpening filters. Pada Smoothing filters terdapat Lowpass filter yang terdiri dari Linear filter (mengambil nilai rata-rata), dan Median filters yang terdiri dari Non-linear filter (mengambil median dari setiap jendela ketetanggaan). Adapun pada Sharpening filters terdapat beberapa jenis dan metode, yaitu Roberts, Prewitt, dan Sobel (Edge Detection) yang bersifat Highpass filter. Deteksi tepi (Edge Detection) pada suatu citra ialah suatu proses yang akan menghasilkan tepi-tepi dari objek-objek citra, yang dimanfaatkan untuk bermacam keperluan diantaranya penggunaan deteksi tepi dalam penggunaannya untuk aplikasi pengenalan fisik mobil. Tujuan dari teknik peningkatan mutu citra ini ialah untuk melakukan pemrosesan terhadap citra agar hasilnya mempunyai kualitas relatif lebih baik dari citra awal untuk aplikasi tertentu. Kata Kunci: Domain Spasial, Mask Processing, dan Edge Detection.
Different Doses of Intraumbilical Oxytocin on the Third Stage of Labor
Authors: Islamy Nurul , Bernolian Nuswil , BasiR Firmansyah , Theodorus Theodorus 
Published: October 2018

Objective: To compare the dose of oxytocin injected intraumbilicalltowards the duration of the third stage, blood loss volume, hemoglobinand hematocrit.

Methods: This study is a prospective randomised study with acontrol. The control group was given an intramuscular injection of10 IU oxytocin. The intervention of the three groups intraumbilicaloxytocin treatment dose of 10 IU, 20 IU and 30 IU diluted in 50 ml ofnormal saline solution and administered intraumbilically. Thesample selection by purposive sampling and the distribution groupbased on systematic random sampling (10 samples each). Data weretaken from the period April 2016-January 2017 with the inclusionand exclusion criteria. Data were analysed using Chi-square, T-test,ANOVA and Post hoc tests.

Results: Characteristics study for variables of age, occupation,parity, education, episiotomy and neonates weight showed homogeneouscharacteristics. The mean duration of the third stage forall groups was between 366.7  159.0 seconds and 440.1  244.99seconds. While the average number of postpartum haemorrhage forall group 61.894  226.3ml and 309.5  110.26 ml. There were nodifferences in the dose of oxytocin on the duration of the thirdstage (p> 0.05) and the amount of bleeding (p> 0.005). There was adifference of haemoglobin between intervention group of oxytocindose of 10 IU and 30 IU intraumbilical (p = 0.031). There was nodifference between the mean hematocrit levels between the groups(p> 0.005).

Conclusion: There were no differences in the dose of oxytocinintraumbilical towards the duration of the third stage, the amountof bleeding and hematocrit levels. The decrease of haemoglobingreater in 30 IU intraumbilical significantly.
Keywords: duration of the third stage, haemoglobin and hematocrit,oxytocin intraumbilical, the amount of bleeding
Human Papilloma Virus16 and 18 Infection and the Cervical Cytology Changes in Combined Hormonal Contraceptive Users
Authors: Darkuthni Merdyana , Tahir Mardiah , Tumedia Josephine L 
Published: October 2018

Objective: To evaluate the correlation between HPV-16 and 18infection and the cervical cytology changes among combinationhormonal contraceptives users.

Methods: A cross-sectional study involved 40 women usingcombined hormonal contraceptive (oral or injection/DMPA contraceptive)and 40 women of non-hormonal contraceptive users wasconducted in Dr. Wahidin Sudirohusodo hospital, some affiliatedhospitals of Department of Obstetrics and Gynecology Faculty ofMedicine, Universitas Hasanuddin and a private clinic in Makassarfrom November 2015 and April 2016. HPV 16 and 18 genotypingin cervix using PCR method and cervical cytology changes usingliquid-based cytology (LBC) method were performed. HPV infectionand cervical cytology changes were analysis based on Fisher’s testand chi-square test.

Results: A significant difference found only in parity (p<0.05)between users and control of baseline characteristics. Neither usersnor control were significantly associated with HPV-16 and 18infection and changes in cervical cytology.

Conclusion: Combined hormonal contraceptives are not correlatedwith HPV-16 and 18 infection and changes in cervical cytology.
Keywords: cervix, combined hormonal contraceptive, human papillomavirus
Effects of Brimonidine on Retinal Pigment Epithelial Cells and Müller Cells Exposed to Amyloid-Beta 1–42 Peptide In Vitro
Authors: Tsao Sean W. , Gabriel Rami , Thaker Kunal , Kuppermann Baruch D. , Kenney M. Cristina 
Published: October 2018

BACKGROUND AND OBJECTIVE:
To evaluate whether brimonidine can prevent cytotoxicity in human retinal pigment epithelial (RPE) and Müller (MIO) cells after exposure to amyloid-beta 1–42 (Aβ42).

MATERIALS AND METHODS:
An in vitro model of geographic atrophy (GA), which is an end-stage complication of age-related macular degeneration (AMD), simulated with the application of Aβ42 in cell culture. RPE and MIO cells were pretreated with brimonidine for 6 hours, then exposed to 10μM Aβ42 for 24 hours. Several concentrations (one time [1×], two times [2×], and five times [5×]) of brimonidine were used to assess for a dose-related effect. Assays were immediately run following the treatment period. 2′,7′-Dichlorofluorescein diacetate was used to assess reactive oxygen species production, the MTT assay was used to assess cell viability, and the JC-1 dye assay was used to assess mitochondrial membrane potential. The main outcome measures were reactive oxygen species (ROS) production, cell viability, and mitochondrial membrane potential (ΔΨm) of RPE and MIO cells following the treatment phase.

RESULTS:
High-dose (5×) brimonidine was capable of reducing ROS production in RPE and MIO cells with exposure to Aβ42. The application of Aβ42 alone did not trigger a rise in ROS production. Brimonidine was unable to rescue cell viability and ΔΨm after exposure to Aβ42 in both cell cultures. Instead, high-dose (5×) brimonidine appeared to increase the toxicity to cell viability and ΔΨm in cultures exposed to Aβ42. However, this was not due to medication toxicity alone, because high-dose (5×) brimonidine without exposure to Aβ42 did not affect the cell viability in both cell types.

CONCLUSION:
Brimonidine may have a role in preventing oxidative cellular injury in AMD. However, this role does not appear to translate into protection against some of the cytotoxic effects observed from this in vitro model of GA. In this cellular model of GA, brimonidine is able to reduce oxidative stress but is unable to rescue cell viability or prevent mitochondrial dysfunction.

[
Ophthalmic Surg Lasers Imaging Retina
. 2018;49:S23–S28.]
Quantitative Fundus Autofluorescence in Non-Neovascular Age-Related Macular Degeneration
Authors: Orellana-Rios Jorge , Yokoyama Sho , Agee Julia M. , Challa Nayanika , Freund K. Bailey , Yannuzzi Lawrence A. , Smith R. Theodore 
Published: October 2018

BACKGROUND AND OBJECTIVE:
To use quantitative fundus autofluorescence (qAF) to analyze different stages of non-neovascular age-related macular degeneration (AMD).

PATIENTS AND METHODS:
In this cohort study, 38 pseudophakic patients and 36 age-matched controls participated. We performed near-infrared, spectral-domain optical coherence tomography and qAF imaging on 31 pseudophakic eyes and controls of participants older than 60 years with non-neovascular AMD phenotypes using the Spectralis HRA + OCT (Heidelberg Engineering, Heidelberg, Germany).

RESULTS:

The patients included in this study had a mean age of 83.9 years, and 35.7% patients were men. Mean qAF was higher in control participants than in all patients with AMD (
P
< .001). According to non-neovascular AMD phenotype, mean qAF levels were significantly lower in eyes with subretinal drusenoid deposits than in control eyes (
P
< .05). The lowest mean qAF was in patients with geographic atrophy.

CONCLUSION:
Quantitative fundus autofluorescence of non-neovascular AMD decreases from normal to early to late AMD, suggesting that loss of lipofuscin fluorophores, not increase, signifies AMD progression.

[
Ophthalmic Surg Lasers Imaging Retina
. 2018;49:S34–S42.]
Aircraft-based observations of isoprene-epoxydiol-derived secondary organic aerosol (IEPOX-SOA) in the tropical upper troposphere over the Amazon region
Authors: Schulz Christiane , Schneider Johannes , Amorim Holanda Bruna , Appel Oliver , Costa Anja , de Sá Suzane S. , Dreiling Volker , Fütterer Daniel , Jurkat-Witschas Tina , Klimach Thomas , Knote Christoph , Krämer Martina , Martin Scot T. , Mertes Stephan , Pöhlker Mira L. , Sauer Daniel , Voigt Christiane , Walser Adrian , Weinzierl Bernadett , Ziereis Helmut , Zöger Martin , Andreae Meinrat O. , Artaxo Paulo , Machado Luiz A. T. , Pöschl Ulrich , Wendisch Manfred , Borrmann Stephan 
Published: October 2018

Abstract. During the ACRIDICON-CHUVA field project
(September–October 2014; based in Manaus, Brazil) aircraft-based in situ
measurements of aerosol chemical composition were conducted in the tropical
troposphere over the Amazon using the High Altitude and Long Range Research
Aircraft (HALO), covering altitudes from the boundary layer (BL) height up to
14.4 km. The submicron non-refractory aerosol was characterized by
flash-vaporization/electron impact-ionization aerosol particle mass
spectrometry. The results show that significant secondary organic aerosol
(SOA) formation by isoprene oxidation products occurs in the upper
troposphere (UT), leading to increased organic aerosol mass concentrations
above 10 km altitude. The median organic mass concentrations in the
UT above 10 km range between 1.0 and
2.5 µg m−3 (referring to standard temperature and pressure;
STP) with interquartile ranges of 0.6 to 3.2 µg m−3 (STP),
representing 78 % of the total submicron non-refractory aerosol particle
mass. The presence of isoprene-epoxydiol-derived secondary organic aerosol
(IEPOX-SOA) was confirmed by marker peaks in the mass spectra. We estimate
the contribution of IEPOX-SOA to the total organic aerosol in the UT to be about
20 %. After isoprene emission from vegetation, oxidation processes occur
at low altitudes and/or during transport to higher altitudes, which may lead
to the formation of IEPOX (one oxidation product of isoprene). Reactive
uptake or condensation of IEPOX on preexisting particles leads to IEPOX-SOA
formation and subsequently increasing organic mass in the UT.
This organic mass increase was accompanied by an increase in the nitrate mass
concentrations, most likely due to NOx production by
lightning. Analysis of the ion ratio of NO+ to NO2+
indicated that nitrate in the UT exists mainly in the form of
organic nitrate. IEPOX-SOA and organic nitrates are coincident with each
other, indicating that IEPOX-SOA forms in the UT either on
acidic nitrate particles forming organic nitrates derived from IEPOX or on
already neutralized organic nitrate aerosol particles.
Power and Ideology Revealed in The Awig-awig (Customary Law) Text of Tenganan Pegringsingan Village: Critical Ecolinguistic Study
Authors: Astawa I Gede , Budiarsa Made , Simpen I Wayan 
Published: October 2018

Awig-awig ‘customary law’ is a written rule which is used to manage customary village organization in Bali. This customary law has a very important role in maintaining the environment in terms of natural environment (palemahan), social environment (pawongan), and spiritual environment (parhyangan). Therefore, every awig-awig made should be based on Tri Hita Karana (THK) concept. The THK is defined as ‘three causes of happiness and prosperity’. In this study, THK is considered as an ecosophy used to judge the existence of lexical items, grammatical contructs, and other linguistic features used in the awig-awig text. In critical discourse, the exisistence of any texts is considered to bring underlying power and ideology. Thus, the written text of the awig-awig belongs to Tenganan Pegringsingan village reveals the form of power fight and ideology. Therefore, this present study was aimed at finding the influence of the power domination and ideology revealed in the awig-awig text. By applying a critical discourse analysis, it was found the influence of the power domination depicted by the use of modality kawasa and wenang ‘may/can’. Most of the linguistic features used in the awig-awig text bring preservative ideologies that need to be promoted. However, in a small part of the linguistic features used in the text, especially in the social environment, implies destructive ideologies, such as marginalization and patriarchal that need to be resisted.
The Use of Hip Radiographs in Primary Care: The Inter-Observer Agreement of Reporting Native Hip Pathology
Authors: Kenyon Peter J. , Perry Daniel , Barrett Michael , Carroll Finton A. , Thomas Glyn 
Published: October 2018

Introduction Plain radiographs are often the first line investigation in identifying the cause of hip pain, though they do not differentiate all morphologically normal and abnormal hips. Interpretation of radiographs is subjective, depending on the patient history and physical signs. A radiological report can be misleading and may lead to, unnecessary radiation exposure, a delay in referral and a delay to definitive treatment. This study was to investigate the inter-observer reliability in the reporting of plain radiographs. Methods Sixty-one consecutive antero-posterior (AP) radiographs of native hips were identified that had been referred to one of the senior authors from the community with “hip pain”. Images were anonymised within PACS (picture archiving and communication system) and reviewed by a consultant orthopaedic surgeon, two consultant musculoskeletal radiologists, one senior orthopaedic registrar and one senior radiology registrar. Each reviewer was given a pre-constructed proforma, and asked to report the radiographs. Results There is a varying degree of ‘agreement’ for many of the commonly used terms on a hip radiograph. Agreement between all observers varied, by description, between 23.3% (CAM Lesion) to 93.3% (AVN). Multi-rater agreement showed Kappa values ranging from 0.12 (poor) to 0.6 (moderate). Overall there were widespread inconsistencies, even amongst the most widely used terms. Conclusion There is variable agreement amongst musculoskeletal radiology and orthopaedic experts when analysing plain radiographs of the native hip. This has implications for utility of reporting and therefore treatment in the community setting.
Plasma Ghrelin and von Willebrand Factor Levels in Patients with Non-Traumatic Osteonecrosis of the Femoral Head
Authors: Li Chenggang , Shen Lin , Yang Yanping , Shuai Bo , Xu Xiaojuan , Ma Chen 
Published: October 2018

Objective Increased evidence indicating ghrelin's direct influence on bone has been reported, but previous studies did not investigate its relationship with osteonecrosis of the femoral head (ONFH) in vivo. Coagulation disorders are considered to play important roles in ONFH. The aim of this study was to investigate the relationship of ghrelin, von Willebrand Factor (vWF) and other potentially relevant indicators with non-traumatic osteonecrosis of the femoral head. Methods Patients with non-traumatic ONFH (including steroid-induced, alcohol-induced, and idiopathic ONFH) and healthy controls were recruited for the study. We evaluated levels of plasma ghrelin and vWF. Other potentially relevant indicators, von Willebrand Factor cleaving protease (vWF-cp), plasminogen activator inhibitor 1 (PAI-1), tissue plasminogen activator (tPA), leptin, C-reactive protein (CRP), and lipid parameters were also assayed. Correlation coefficients and logistic regression models were used to assess the associations. Results Patients with non-traumatic ONFH had significantly lower ghrelin levels, higher vWF, PAI-1, CRP levels than those in healthy controls. Ghrelin level was negatively correlated with vWF after adjustment for other variables. Logistic regression model revealed that non-traumatic ONFH was independently associated with plasma ghrelin and vWF. Conclusions This study indicates that plasma ghrelin, vWF and PAI-1 levels were changed in patients with non-traumatic ONFH. Ghrelin in combination with vWF may prove to be involved in the pathogenesis of non-traumatic ONFH.
Turkish Adaptation of Behavioral Regulations in Sports Questionaire and Reviewing Psychometry Properties: Validation and Reliability Study
Authors: Çetinkaya Turan , Mutluer Ceren 
Published: October 2018

Purpose of this study is to adapt Behavioral Regulation in Sports Questionaire (BRSQ) which developed by Lonsdale, Hodge and Rose (2008) in Turkish and review psychometry properties. The scale consists of 24 items and 6 subdimension including intrinsic motivation, integrated regulation, identitied regulation, introjected regulation, external regulation and amotivation. Study group consists of total 681 student- athlete whom are licensed athletes and study at Physical Education and Sports College of Ahi Evran University, Erciyes University, Dumlupinar University and Çanakkale 18 Mart University. In order to determine psychometry properties of scale internal consistency, material and factor analysis and test- retest methods were applied. Cronbach alpha internal consistency coefficient of the measurement determined as follows; 0.790 for total points, 0.856 for intrinsic motivation subdimension, 0.838 for integrated regulation subdimension, 0.862 for identitied regulation subdimension, 0.740 for introjected regulation subdimension, 0.788 for external regulation subdimension and 0.800 for amotivation subdimension. In the analyzes performed, the data obtained from the exploratory and confirmatory factor analysis confirmed the 6-factor structure of the scale. In addition, scale-based analyzes yielded high test-retest scores. In this sense, it is considered that the scale is a valid and reliable measurement tool for the Turkish sample group.
THE EFFECTS OF COGNITIVE BEHAVIORAL THERAPY ON SMOKING BEHAVIOR AND ANXIETY IN HEADS OF FAMILY WHO SMOKE
Authors: Hargiana Giur , Keliat Budi Anna , Mustikasari Mustikasari 
Published: October 2018

Indonesia is the fifth largest producer of cigarettes and has the third highest number of smokers in the world. This has potential biological, psychological, and social consequences. The aims of this study were to investigate the effects of Cognitive Behavioral Therapy (CBT) on smoking behavior and anxiety. Quasi-experimental non-equivalent control group pretest-posttest design was used. A total of 80 respondents were selected at random from 10 districts in proportion to the number of smokers in each district. Respondents completed questionnaires and received a course of CBT conducted over five meetings. There was a significant decrease smoking behavior and anxiety (p< 0.05) in the intervention group. Smoking behavior, nicotine dependence, and anxiety in male heads of family who smoke and who received CBT were significantly lower than in control group. The decreases in smoking behavior and anxiety were significantly correlated (p< 0.05). The study reveals, CBT can effectively change smoking habits as well as reduce anxiety. Keyword: anxiety, smoking behavior, cognitive behavioral therapy Abstrak Pengaruh Cognitive Behavior Therapy Terhadap Perilaku Merokok dan Ansietas pada Kepala Keluarga dengan Perilaku Merokok. Indonesia sebagai penghasil rokok terbesar ke-5 dan memiliki jumlah perokok terbanyak ke-3 di Dunia, hal tersebut memunculkan masalah secara biologis, psikologis maupun sosial. Tujuan penelitian ini untuk mengetahui pengaruh dari cognitive behavior therapy terhadap perubahan perilaku merokok dan ansietas. Metode penelitian menggunakan desain quasi experiment non-equivalent control group pre-test-post test. Sampel pengambilan secara proporsional random dengan jumlah 80 responden. Pengumpulan data dengan menggunakan kuesioner kemudian responden dilakukan tindakan cognitive behavior therapy dengan lima kali pertemuan. Hasil penelitian menunjukkan penurunan perilaku merokok dan ansietas secara bermakna (p< 0,05) pada kelompok intervensi. Penurunan perilaku merokok, tingkat ketergantungan nikotin dan ansietas kepala keluarga dengan perilaku merokok yang mendapatkan cognitive behavior therapy lebih besar secara bermakna (p< 0,05) dibandingkan dengan yang tidak mendapatkan cognitive behavior therapy. Penurunan perilaku merokok dan ansietas berhubungan secara bermakna (p< 0,05). Direkomendasikan untuk menerapkan cognitive behavior therapy perokok oleh perawat yang mempunyai kompetensi. Kata Kunci: ansietas, perilaku merokok,cognitive behavior therapy