bluuebunny/crossref_metadata_2025_split huggingface dataset:
EDUCAÇÃO, COMPLEXIDADE E AMBIENTE: UM DIÁLOGO POSSÍVEL
Authors: Jaskiw Eliandra Francielli Bini , Lautert Luiz Fernando de Carli , Gerhardt Renata 
Published: June 2019

Esta pesquisa de natureza teórica tem como propósito investigar e apresentar ideias convergentes sobre o pensamento complexo. O pensamento complexo é uma teoria relativamente nova e vem sendo inserida na educação e na análise de questões relacionadas ao meio ambiente. Para tanto, a partir do estudo e análise de textos específicos de autores que visam à complexidade das relações, realiza-se um diálogo entre o pensamento de Edgar Morin, Paulo Freire, Milton Santos, Leonardo Boff, Fritjot Capra, Enrique Leff e Jared Diamond, incluindo autores citados por eles em suas obras analisadas. A princípio são analisadas as questões acerca de uma educação emancipadora, finalizando com análises sobre colapsos ambientais e a proposta do Bem Viver. Todas as questões propostas estão influenciadas pelo pensamento complexo, das relações sistêmicas. A reflexão apresentada pode subsidiar a discussões e debates entre profissionais vinculados à educação e ao meio ambiente de modo a contribuir para uma reorientação e humanização das práticas educativas.
Wat Nederland meer kan doen om gebouwen sneller en beter toegankelijk te maken (ook zonder het VN-verdrag Handicap)
Authors: Laan O. 
Published: June 2019

Wat Nederland meer kan doen om gebouwen sneller en beter toegankelijk te maken (ook zonder het VN-verdrag Handicap)
Nederland heeft in 2016 het VN-verdrag Handicap geratificeerd. Artikel 9 van het verdrag verplicht Nederland om bestaande en nieuwe gebouwen geleidelijk en proactief volledig toegankelijk te maken voor personen met een handicap. Volgens de overheid is het realiseren van een inclusieve samenwerking met de implementatie van het verdrag geen kwestie van op landelijk niveau ‘op een knop drukken’, maar vooral een proces van cultuurverandering en vernieuwing dat zijn beslag moet krijgen in de samenleving, met name op lokaal niveau en met inachtneming van ieders verantwoordelijkheid. Dat neemt niet weg dat Nederland veel meer kan doen om gebouwen sneller en beter toegankelijk te maken. Ook zonder het VN-verdrag Handicap.
Het managen van communicatiefouten in verdachtenverhoren en crisisonderhandelingen
Authors: Oostinga Miriam 
Published: June 2019

Communication error management in suspect interviews and crisis negotiations
A vast amount of research focuses on what should be said and done in suspect interviews and crisis negotiations to make the suspect cooperate. This article discusses the most important findings of five empirical studies that focus on the situation in which something wrong is said, which may undermine cooperation. The findings show that communication errors have both positive and negative effects on the suspect and law enforcement officer. Yet, it is the verbal response of the law enforcement officer that determines its overall direction. It is important to acquire knowledge on this topic, as there is a likely chance of making communication errors in these high-stake interactions and with these insights you can prepare yourself for when this situation occurs.
Hvordan lages barn? Bildebøker for barn om hvordan barn blir til – How to Make Children? Picturebooks for Children About How to Make A Baby
Authors: Maagerø Eva , Øines Anne Marie 
Published: June 2019

I denne artikkelen analyseres fire bildebøker for barn der temaet er hvordan barn blir til. Målet er å undersøke hvordan voksensamfunnet formidler dette tilsynelatende tabubelagte og sensitive emnet til små barn gjennom verbal-språk og bilde. Spørsmålene som besvares i analysen, er: Hvilke litterære strategier benyttes i de fire bildebøkene for å informere om hvordan barn blir til, og hva kan en analyse av bilde og verbalspråk av utvalgte oppslag si om fordelingen av informasjon i de to modalitetene? De fire bøkene er Slik får man et barn av Per Holm Knudsen (1971), Hvor ble det av Benny? av Nicholas Allan (2004), Da Emma ble Emma - historien om hvordan et barn blir til av Peter Gotthardt og Kirsten Raagaard (2009) og Hvordan lager man en baby? av Anna Fiske (2019). I analysen undersøker vi i hvilken grad fortelling er brukt som en strategi for å formidle emnet, mens de utvalgte oppslagene analyseres ut fra et sosialsemiotisk rammeverk. Det viser seg at tre av bøkene har en tydelig fortellingsstruktur om enn på ulik måte. Analysen av oppslagene viser at det sannsynligvis er enklere å ta opp seksualitet gjennom modaliteten verbalspråk enn gjennom bilde. Funnene samsvarer med annen forskning på bildebøker om seksualitet.AbstractIn this article, four picturebooks for children with the topic how babies are made are analyzed. The aim is to investigate how adults present this controversial and sensitive theme to young children through verbal language and image. The analysis aims to answer the following research questions: Which literary strategies are used in the four picturebooks to inform about how babies are made, and what can an analysis of image and verbal language of selected spreads tell about the distribution of information in the two modes? The four books are How to get a child by Per Holm Knudsen (1971), Where Willi went by Nicholas Allan (2004), When Emma became Emma – the story about how a child is made by Peter Gotthardt and Kirsten Raagaard (2009) and How do you make a baby? by Anna Fiske (2019)[1]. The four books were analyzed to find out to which degree a narrative strategy was used, while a social semiotic framework was used to analyze the selected spreads. Three of the four books used a narrative structure to present the topic, but in different ways. The analysis of the spreads shows that verbal language carries more semantic weight than images do when it comes to sexuality. The findings support findings from other research conducted about sexuality. [1] Three titles are translated into English by the authors of the article. Where Willi went is the book’s original title.
Risk Factors for Overweight in early ages: longitudinal design with Spanish Preschoolers
Authors: Pérez-Bonaventura Iris , Granero Roser , Ezpeleta Ascaso Lourdes 
Published: June 2019

Previous studies have shown that there are several significant early-life risk factors associated with childhood overweight. However, research has mainly focused on school-aged children. The aim of this study is to identify risk factors in early life for overweight in a community sample of Spanish preschoolers. A sample of 622 three-year-olds was monitored until the age of 5, and their height and weight were registered annually. Overweight status was defined by World Health Organization standards. A large set of risk factors including sociodemographic variables, family structure, pregnancy, birth, postnatal period, school and neighborhood were measured through semi-structured interviews. Stepwise logistic regressions created predictive models with the best predictors of overweight for each age group. This is the first longitudinal study to examine a large set of risk factors among Spanish preschoolers. Several potential early risk factors in preschool children were associated with later overweight: high birth weight, ethnicity, excess screen time, low attention span, maternal smoking during pregnancy, inconsistent discipline, fewer rules, corporal punishment and parents psychopathology. Among them, the most powerful factor was high birth-weight (odds ratio = 1.89 at age 3, 1.87 at age 4, and 2.35 at age 5), underlining the importance of weight monitoring from postpartum and routine screening for overweight in children who have high birth weight. With the increasing prevalence of overweight in children at early ages, understanding the determinants for overweight risk becomes crucial for public health professionals and policy-makers in order to implement effective prevention and intervention programs
Exploring the feasibility, sustainability and the benefits of the GrACE + GAIT exercise programme in the residential aged care setting
Authors: Fien Samantha , Henwood Tim , Climstein Mike , Rathbone Evelyne , Keogh Justin W.L. 
Published: June 2019

Background
The feasibility and benefits of a 24-week targeted progressive supervised resistance and weight-bearing exercise programme (Group Aged Care Exercise + GAIT (GrACE + GAIT)) in the residential aged care (RAC) setting was investigated as very little peer-reviewed research has been conducted in relation to exercise programmes of this duration in this cohort.

Methods
A quasi-experimental study design consisting of two groups (control and exercise) explored a 24-week targeted progressive supervised resistance and weight-bearing exercise programme (GrACE + GAIT) in two RAC facilities in Northern New South Wales, Australia. A total of 42 adults consented to participate from a total of 68 eligible residents (61.7%). The primary outcome measures were feasibility and sustainability of the exercise programme via intervention uptake, session adherence, attrition, acceptability and adverse events. Secondary measures included gait speed and the spatio-temporal parameters of gait, handgrip muscle strength and sit to stand performance.

Results
Twenty-three residents participated in the exercise intervention (mean (SD) 85.4 (8.1) years, 15 females) and 19 in the control group (87.4 (6.6) years 13 females). Exercise adherence was 79.3%, with 65% of exercise participants attending ≥70% of the sessions; 100% of those originally enrolled completed the programme and strongly agreed with the programme acceptability. Zero exercise-related adverse events were reported. ANCOVA results indicated that post-intervention gait speed significantly increased (p < 0.001) with an 18.8% increase in gait speed (m/s).

Discussion
The GrACE + GAIT programme was shown to be feasible and significantly improve adults living in RAC facilities gait speed, handgrip strength and sit to stand performance. These results suggest that the GrACE + GAIT programme is suitable for use in the RAC sector and that it has the potential to reduce disability and improve function and quality of life of the residents.
Value Addition to Beans: The Case of Bean Balls “Akara” Production in Idemili South Local Government of Anambra State, Nigeria
Authors: Nwankwo T. N. , Okoli T. O. , Ugwumba C. O. A. 
Published: June 2019

Aims: The study examined socio-economic characteristics of the bean balls producers, the profitability of production, determinants of profit, reasons for starting the business and constraints to production of bean balls in Idemili South Local Government Area of Anambra State, Nigeria. The great need to help homemakers in Nigeria better appreciate and prepare cowpea bean balls as snacks for income generation and women empowerment in Nigeria informed this study.
Study Design: Multi-stage, purposive and random sampling techniques were used to select 50 respondents. Data were collected using structured questionnaire and analyzed by means of descriptive and inferential statistics.
Results: Findings on socio-economic factors of the respondents gave mean age, education level and years of experience of 42.4years, 13.5years and 8.9 years respectively; the majority (92%) of the respondents were females, the majority (60%) married and most (70%) had a household size of 4-6 persons. The enterprise proved profitable with monthly mean net income and net return on investment values of ₦75,990 and 0.39 respectively. Significant determinants of net production returns were gender, educational level and costs of inputs. Main reasons for starting the business were a scarcity of job, profitable nature of the business, high demand and small start-up capital. Serious constraints to production of bean balls in the area were conjunctivitis due to emitted smoke, high and unstable price of raw materials and high cost of production. Policy measures such as bulk purchasing of beans, regulation of market prices of the product, provision of infrastructures (water, electricity), use of cooking gas as a source of heat would mitigate the problems, improve productivity, output and enterprise profitability.
Conclusion: The bean ball production proved to be a profitable enterprise in the study area. Nevertheless, the efficiency and profitability would be improved if the constraints identified by the study are addressed as it will encourage many more people especially young, active and viable individuals, to venture into the enterprise.
Quantitative Structure–Activity Relationship and Molecular Docking Studies of Imidazolopyrimidine Amides as Potent Dipeptidyl Peptidase-4 (DPP4) Inhibitors
Authors: Emami Leila , Sabet Razieh , Sakhteman Amirhossein , Zade Mehdi Khoshnevis 
Published: June 2019

Type 2 diabetes (T2DM) is a metabolic disorder disease and DPP-4 inhibitors are a class of oral hypoglycemic that blocks the dipeptidyl peptidase-4 (DPP-4) enzyme. DPP-4 inhibitors reduce glucagon and blood glucose levels and don’t have side effects such as hypoglycemia or weight gain. In this paper, a series of imidazolopyrimidine amides analogues as DPP4 inhibitors were selected for quantitative structure-activity relationship (QSAR) analysis and docking studies. A collection of chemometric methods such as multiple linear regression (MLR), factor analysis-based multiple linear regression (FA-MLR), principal component regression (PCR), genetic algorithm for variable selection-MLR (GA-MLR) and partial least squared combined with genetic algorithm for variable selection (GA-PLS), were conducted to make relations between structural features and DPP4 inhibitory of a variety of imidazolopyrimidine amides derivatives. GA-PLS represented superior results with high statistical quality (R2 = 0.94 and Q2 = 0.80) for predicting the activity of the compounds. Docking studies of these compounds reveals and confirms that compounds 15, 18, 25, 26, and 28 are introduced as good candidates for DPP-4 inhibitors were introduced as a good candidate for DPP-4 inhibitory compounds.
Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor
Authors: Thysell Elin , Vidman Linda , Ylitalo Erik Bovinder , Jernberg Emma , Crnalic Sead , Iglesias‐Gato Diego , Flores‐Morales Amilcar , Stattin Pär , Egevad Lars , Widmark Anders , Rydén Patrik , Bergh Anders , Wikström Pernilla 
Published: June 2019

Bone metastasis is the lethal end‐stage of prostate cancer (PC), but the biology of bone metastases is poorly understood. The overall aim of this study was therefore to explore molecular variability in PC bone metastases of potential importance for therapy. Specifically, genome‐wide expression profiles of bone metastases from untreated patients (n = 12) and patients treated with androgen‐deprivation therapy (ADT, n = 60) were analyzed in relation to patient outcome and to morphological characteristics in metastases and paired primary tumors. Principal component analysis and unsupervised classification were used to identify sample clusters based on mRNA profiles. Clusters were characterized by gene set enrichment analysis and related to histological and clinical parameters using univariate and multivariate statistics. Selected proteins were analyzed by immunohistochemistry in metastases and matched primary tumors (n = 52) and in transurethral resected prostate (TUR‐P) tissue of a separate cohort (n = 59). Three molecular subtypes of bone metastases (MetA‐C) characterized by differences in gene expression pattern, morphology, and clinical behavior were identified. MetA (71% of the cases) showed increased expression of androgen receptor‐regulated genes, including prostate‐specific antigen (PSA), and glandular structures indicating a luminal cell phenotype. MetB (17%) showed expression profiles related to cell cycle activity and DNA damage, and a pronounced cellular atypia. MetC (12%) exhibited enriched stroma–epithelial cell interactions. MetB patients had the lowest serum PSA levels and the poorest prognosis after ADT. Combined analysis of PSA and Ki67 immunoreactivity (proliferation) in bone metastases, paired primary tumors, and TUR‐P samples was able to differentiate MetA‐like (high PSA, low Ki67) from MetB‐like (low PSA, high Ki67) tumors and demonstrate their different prognosis. In conclusion, bone metastases from PC patients are separated based on gene expression profiles into molecular subtypes with different morphology, biology, and clinical outcome. These findings deserve further exploration with the purpose of improving treatment of metastatic PC.
Dual‐Action Flexible Antimicrobial Material: Switchable Self‐Cleaning, Antifouling, and Smart Drug Release
Authors: Děkanovský Lukáš , Elashnikov Roman , Kubiková Markéta , Vokatá Barbora , Švorčík Václav , Lyutakov Oleksiy 
Published: June 2019

AbstractA switchable material with a smart antimicrobial dual‐action functionality, which is based on a highly stretchable silicon polymer gradiently doped with polyyrrole, is proposed. The material exhibits superhydrophobic and self‐cleaning properties, high aerophilicity as well as the possibility of smart, electrically triggerable release of an incorporated drug. During the immersion of the material in water, an air gap is formed on its surface which prevents a formation of biofouling, attachment of microorganisms, and burst release of the incorporated drug. An application of external electric field switches the surface properties from the superhydrophobic to highly hydrophilic state that enables a wetting of the material surface and electrically triggered release of a loaded drug. After the electric field switching off and sample drying, the material surface returns to its intrinsic superhydrophobic state with the original self‐cleaning properties so that the material surface can be simply cleaned, removing the bacteria. High flexibility and stretchability are additional favorable properties of the proposed smart antimicrobial material, making it a suitable candidate for a range of medical and related applications.
Self‐Assembly of rGO Coated Nanorods into Aligned Thick Films
Authors: Modarres Mohammad Hadi , Kosasih Felix Utama , Ducati Caterina , De Volder Michael 
Published: June 2019

AbstractSelf‐assembly is a very effective and popular method to create monolayers or thin films of aligned nanorods and ellipsoids. Nevertheless, there has been little attention to forming thick films of aligned nanorods using this approach. Here, the self‐assembly mechanism of nanorods coated with reduced graphene oxide in thick films with both a surface and a bulk alignment process is underpinned. The alignment method is robust and results in films with up to 50% higher volumetric density compared to nonaligned films of the same material. To optimize the coating process, an image processing script is implemented that quantifies the quality of the alignment based on a fast Fourier transform of nanorod electron microscope images. Based on this analysis, parameters are identified that influence the alignment to optimize the process for obtaining large area domains. Finally, dip‐coating, blade casting and zone coating are tested and compared and lithographically patterned substrates are used to template the self‐assembly process.
Soldering Grain Boundaries Yields Inverted Perovskite Solar Cells with Enhanced Open‐Circuit Voltages
Authors: Li Yunlong , Sun Weihai , Gu Feidan , Ouyang Dan , Bian Zuqiang , Liu Zhiwei , Choy Wallace C. H. , Kelly Timothy L. 
Published: June 2019

AbstractGrain boundaries (GBs) are one of the major sources of defects in a polycrystalline perovskite solar cell and can greatly increase the rate of charge carrier recombination. In the push to optimize the efficiency of perovskite solar cells, it is therefore extremely important to maximize the grain size and minimize the number of GBs. In the present work, the number of GBs is effectively reduced by introducing a suitable number of formamidinium and chloride ions into the methylammonium lead iodide (MAPbI3) absorber layer. Inverted perovskite solar cells, using NiOx
nanocrystals as the low‐temperature‐fabricated hole transport layer, are prepared; the champion cell has an efficiency of 19.6%. This work demonstrates a simple method of minimizing the number of grain boundaries, which is critical to the future development of this technology.
Perforated and Endothelialized Elastomeric Tubes for Vascular Modeling
Authors: Duchamp Margaux , Bakht Syeda Mahwish , Ju Jie , Yazdi Iman K. , Zhang Weijia , Zhang Yu Shrike 
Published: June 2019

AbstractHerein, the fabrication of a tubular polydimethylsiloxane (PDMS) platform containing arrays of small pores on the wall for modeling blood vessels in vitro is reported. The thin PDMS tubes are produced following a templating approach, while the pores are subsequently generated using focused laser ablation. As such, when these perforated PDMS tubes are populated with a monolayer of endothelial cells on the interior surfaces and embedded within an extracellular matrix (ECM)‐like environment, the endothelial cells can sprout out from the tubes into the surrounding matrix through the open pores. When a pair of perforated PDMS tubes is placed in parallel in the matrix, formation of an interconnected network of microvasculature or larger vessels occurs, which seems to be dependent on the flow dynamics within the PDMS tubes. Moreover, when cocultured with tumor spheroids, the onset of tumor angiogenesis is observed. Our perforated and endothelialized PDMS tubes are believed to enable convenient vascular modeling in vitro and will likely contribute to improved biological studies as well as therapeutic screening in the future with further optimizations.
Surface‐Wrinkle‐Modified Graphite Felt with High Effectiveness for Vanadium Redox Flow Batteries
Authors: Chen Zehua , Gao Yu , Zhang Chuanxiang , Zeng Xianxiang , Wu Xiongwei 
Published: June 2019

AbstractSurface‐wrinkle‐modified graphite felt (GF) with abundant N and O is prefabricated by a hydrothermal method followed by calcination, and its surface morphology, elemental composition, and electrochemical properties are characterized by scanning electron microscopy, Raman spectroscopy, X‐ray photoelectron spectroscopy, cyclic voltammetry, electrochemical impedance spectroscopy, and charge/discharge tests. The highly folded coating has excellent wettability, abundant catalytic sites, a fast ion‐diffusion rate, ultralow interface transfer resistance, and high catalytic activity for VO2+/VO2+ and V2+/V3+ reaction couples. Compared with the original GF, the modified GF greatly increases the redox reversibility of the VO2+/VO2+ and V2+/V3+ couples according to cyclic voltammetry profiles. The cathodic and anodic peak potential difference for VO2+/VO2+ substantially decreases from 542 to 388 mV. A battery based on surface‐wrinkle‐modified GF exhibits overall improved efficiency, higher power density, and a high reversible efficiency with a stable average energy efficiency of 78% at a current density of 150 mA cm−2 for 200 charge/discharge cycles.