bluuebunny/crossref_metadata_2025_split huggingface dataset:
Taking into Account Local Conditions in the Development of Climate Standards in Construction
Authors: Volkova N. 
Published: December 2018

Abstract
Accuracy of climate assessment is one of the most difficult and at the same time the most urgent tasks of the world science. On the basis of interaction of a large number of various meteorological factors the normative indicators used at design, construction and operation of objects, the choice of constructive decisions of products and characteristics of materials are developed. Energy saving and safety are realized through provision of climatic parameters, qualitative technology of products and correct operation of construction objects.
The specificity of the orographic features of the construction site of JSC “Sayanskhimplast” has led to the development of climate regulations, taking into account the local conditions of the territory. In work were used materials of the Irkutsk Department of meteorological service, data of special surveys conducted by Zapsibnigni and materials thermoanemometer the site area. During the research the observational data of the average daily temperature of the atmospheric air of the construction site “Sayanskhimplast” were taken into account. Methods of calculation of meteorological parameters, developed in the Institute of building physics RAASN, it was also a comparison of the extremes of winter temperatures and representative cities, which has allowed the development of climate regulations for the city of Sayansk.
Duration of Fame and Extent of Semantic Knowledge of Famous Names in Cognitively Intact Older Adults
Authors: Kalscheur Emily J , Kandah Cassandra C , Woodard John L , Song Woojin , Seidenberg Michael 
Published: December 2018

Abstract

Objective
The greater resilience of older memories relative to recent memories has primarily been demonstrated in clinical groups, but this phenomenon has been less extensively examined in cognitively intact older adults. Additionally, most studies of person-identity have only examined recognition or familiarity of a famous face or name, and there has been less systematic study of access to more specific person-identity semantic knowledge. The current study examined the effect of both memory age and extent of semantic knowledge on famous name recognition and retrieval of person-identity biographical information in healthy older adults.

Method
We examined recognition accuracy and response time of famous names at three time epochs (recent fame, transitory fame and enduring fame) in cognitively intact older adults. We also compared access to semantic knowledge that differed on the degree of specificity of biographical information: categorical, associative, and attribute knowledge.

Results
As predicted, participants recognized transitory famous names more quickly and accurately than recent famous names. Additionally, participants recognized enduring famous names more accurately than transitory famous names and recent names. We also found that categorical semantic knowledge was accessed more quickly and accurately than semantic knowledge for associative and attribute information.

Conclusions
These findings provide data on the cognitive structure and retrieval of person-identity knowledge and memory age in older cognitively intact individuals.
Sequence Variation Associated with SLC12A5 Gene Expression Is Linked to Brain Structure and Function in Healthy Adults
Authors: Gregory Michael D , Kippenhan J Shane , Callicott Joseph H , Rubinstein Daniel Y , Mattay Venkata S , Coppola Richard , Berman Karen F 
Published: December 2018

Abstract
A single-nucleotide polymorphism in the promoter region of the Matrix Metalloproteinase-9 (MMP9) gene, rs3918242, has been shown to affect MMP9 expression in macrophages and was associated with schizophrenia by two independent groups. However, rs3918242's effects on MMP9 expression were not replicable in cell lines or brain tissue. Additionally, publically available data indicate that rs3918242 genotype is related not to MMP9 expression, but rather to expression of SLC12A5, a nearby gene coding for a K+/Cl- cotransporter, whose expression has also been related to schizophrenia. Here, we studied brain structure and function in healthy participants stratified by rs3918242 genotype using structural MRI (N = 298), functional MRI during an N-back working memory task (N = 554), and magnetoencephalography (MEG) during the same task (N = 190). We found rs3918242 was associated with gray matter volume (GMV) in the insula and dorsolateral prefrontal cortex bilaterally, closely replicated in discovery and replication samples; and with inferior parietal lobule (IPL) GMV when the samples were meta-analytically combined. Additionally, using both fMRI and MEG, rs3918242 was associated with right IPL working memory-related activation, replicated in two cohorts and across imaging modalities. These convergent results provide further impetus for examinations of the relationship of SLC12A5 with brain structure and function in neuropsychiatric disease.
Burden of Streptococcus pneumoniae Sepsis in Children After Introduction of Pneumococcal Conjugate Vaccines: A Prospective Population-based Cohort Study
Authors: Asner Sandra A , Agyeman Philipp K A , Gradoux Eugénie , Posfay-Barbe Klara M , Heininger Ulrich , Giannoni Eric , Crisinel Pierre A , Stocker Martin , Bernhard-Stirnemann Sara , Niederer-Loher Anita , Kahlert Christian R , Hasters Paul , Relly Christa , Baer Walter , Aebi Christoph , Schlapbach Luregn J , Berger Christoph 
Published: December 2018

AbstractBackgroundPopulation-based studies assessing the impact of pneumococcal conjugate vaccines (PCV) on burden of pneumococcal sepsis in children are lacking. We aimed to assess this burden following introduction of PCV-13 in a nationwide cohort study.MethodsThe Swiss Pediatric Sepsis Study (September 2011 to December 2015) prospectively recruited children <17 years of age with blood culture-proven sepsis due to Streptococcus pneumoniae, meeting criteria for systemic inflammatory response syndrome. Infection with vaccine serotype in children up to date with PCV immunization was defined as vaccine failure. Main outcomes were admission to pediatric intensive care unit (PICU) and length of hospital stay (LOS).ResultsChildren with pneumococcal sepsis (n = 117) accounted for a crude incidence of 2.0 per 100 000 children (95% confidence interval [CI] 1.7–2.4) and 25% of community-acquired sepsis episodes. Case fatality rate was 8%. Forty-two (36%) patients required PICU admission. Children with meningitis (29; 25%) were more often infected by serotypes not included in PCV (69% vs 31%; P < .001). Sixteen (26%) of 62 children up to date with PCV immunization presented with vaccine failure, including 11 infected with serotype 3. In multivariable analyses, children with meningitis (odds ratio [OR] 6.8; 95% CI 2.4–19.3; P < .001) or infected with serotype 3 (OR 2.8; 95% CI 1.1–7.3; P = .04) were more often admitted to PICU. Children infected with serotype 3 had longer LOS (β coefficient 0.2, 95% CI .1–1.1; P = .01).ConclusionsThe incidence of pneumococcal sepsis in children shortly after introduction of PCV-13 remained substantial. Meningitis mostly due to non-vaccine serotypes and disease caused by serotype 3 represented significant predictors of severity.
Clinical Practice Variation Among Adult Infectious Disease Physicians in the Management of Staphylococcus aureus Bacteremia
Authors: Liu Catherine , Strnad Luke , Beekmann Susan E , Polgreen Philip M , Chambers Henry F 
Published: December 2018

Abstract
Infectious disease management of Staphylococcus aureus bacteremia (SAB) was surveyed through the Emerging Infections Network. Although there were areas of consensus, we found substantial practice variation in diagnostic evaluation and management of adult patients with SAB. These findings highlight opportunities for further research and guidance to define best practices.
Intensity-modulated radiotherapy at high-volume centers improves survival in patients with esophageal adenocarcinoma receiving trimodality therapy
Authors: Yang G Q , Mhaskar R , Rishi A , Naghavi A O , Frakes J M , Almhanna K , Fontaine J , Pimiento Jose M , Hoffe Sarah E 
Published: December 2018

Summary
The standard of care trimodality therapy for resectable locally advanced esophageal adenocarcinoma is complex and necessitates multidisciplinary care and expertise. In this work, it is hypothesized that facility clinical volume and utilization of intensity-modulated radiotherapy (IMRT) may influence outcomes. The National Cancer Data Base was queried for patients with cT1-4-N0-3 M0 esophageal adenocarcinoma undergoing trimodality therapy from 2004 to 2013 (n = 2445). All patients received chemoradiation followed by esophagectomy at a Commission on Cancer facility. The facility volume was categorized into tertiles: high-volume centers (HVCs) in the highest 25th percentile of cases per year, intermediate-volume centers (IVCs) with the next highest 25th percentile of cases, and low- and very low-volume centers (LVCs) in the lowest 50th percentile. Overall survival (OS) was estimated using Kaplan–Meier methods and Cox proportional hazard regression. Propensity score matching to balance patient characteristics between volume centers was performed. Subgroup analysis was done comparing IMRT versus 3D conformal radiotherapy. The median follow-up was 26 months. Treatment at an HVC (hazard ratio 0.63, 95% CI 0.49–0.81, P < 0.001) was found to be independently associated with improved overall survival in multivariable analysis. Three-year OS was 58.4%, 46.2%, and 47.5% for HVCs, IVCs, and LVCs, respectively (P < 0.001). Patients at HVCs were more likely to receive IMRT over 3D chemoradiation (CRT; OR 3.45, 95% CI 2.4–5.0, P < 0.001). Patients treated using IMRT at HVCs had improved OS compared to those treated at IVCs or LVCs (HR 0.68, 95% CI 0.52–0.90, P < 0.01), while patients treated with 3D CRT at HVCs had no survival advantage over those at IVCs or LVCs (P = 0.28). Patients with locally advanced esophageal adenocarcinoma treated with IMRT and at HVCs appear to have improved survival.
The overall metastatic rate in early esophageal adenocarcinoma: long-time follow-up of surgically treated patients
Authors: Oetzmann von Sochaczewski C , Haist T , Pauthner M , Mann M , Fisseler-Eckhoff A , Braun S , Ell C , Lorenz D 
Published: December 2018

SUMMARYThe overall metastatic potential of surgically treated early esophageal adenocarcinoma has not been studied in detail. This paper therefore assessed lymph node metastases at surgery, loco regional and distant metastases, in order to assess the metastatic potential of early esophageal adenocarcinoma. Two hundred and seventeen patients (53 T1a, 164 T1b; median follow-ups 87 and 75 months, 187 males) diagnosed with early esophageal adenocarcinoma and treated with esophagectomy in our tertiary center's database between July 2000 and December 2015 were included. All metastatic events were retrospectively analyzed, their topographic distribution was assessed, and the overall metastatic rate was calculated. Lymph node metastases occurred in 39 patients (18%) and 29 (13.4%) developed recurrences. Lymph node metastases were absent in m1 and m2 tumors and rare in m3 (1/18), m4 (5/21), and sm1 (4/42), but more frequent in sm2 (11/44) and sm3 tumors (18/78). Locoregional recurrences were exceedingly rare in m3 (2/18), m4 (1/21), sm1 (1/42), and sm2 (2/44), but frequent in sm3 (12/78). In contrast, distant metastases were more frequent with 2/18 in m3, 1/21 in m4, 4/42 in sm1, 4/44 in sm2, and 13/78 in sm3. Overall metastatic rates of 11.9% in sm1 (submucosal layer divided into equal thirds), 27.3% in sm2, and 32.1% in sm3 tumors were calculated. This first report of the metastatic potential of early esophageal adenocarcinoma provides a meticulous assessment of the overall metastatic risk. Metastatic events pose a relevant risk in surgically treated patients with esophageal adenocarcinoma with distant metastases being more frequent than locoregional recurrences.
Outcomes of octogenarians with esophageal cancer: an analysis of the National Cancer Database
Authors: Bakhos C T , Salami A C , Kaiser L R , Petrov R V , Abbas A E 
Published: December 2018

SUMMARYThe optimal treatment of esophageal cancer in octogenarians is controversial. While the safety of esophagectomy has been demonstrated in elderly patients, surgery and multimodality therapy are still offered to a select group. Additionally, the long-term outcomes in octogenarians have not been thoroughly compared to those in younger patients. We sought to compare the outcomes of esophageal cancer treatment between octogenarians and non-octogenarians in the National Cancer Database (2004–2014). The major endpoints were early postoperative mortality and long-term survival. A total of 107,921 patients were identified [octogenarian—16,388 (15.2%)]. Compared to non-octogenarians, octogenarians were more likely to be female, of higher socioeconomic status, and had more Charlson comorbidities (p &lt; 0.001 for all). Octogenarians were significantly less likely to undergo esophagectomy (11.5% vs. 33.3%; p &lt; 0.001) and multimodality therapy (2.0% vs. 18.5%; p &lt; 0.001), a trend that persisted following stratification by tumor stage and Charlson comorbidities. Both 30-day and 90-day mortality were higher in the octogenarian group, even after multivariable adjustment (p ≤ 0.001 for both). Octogenarians who underwent multimodality therapy had worse long-term survival when compared to younger patients, except for those with stage III tumors and no comorbidities (HR: 1.29; p = 0.153). Within the octogenarian group, postoperative mortality was lower in academic centers, and the long-term survival was similar between multimodality treatment and surgery alone (HR: 0.96; p = 0.62). In conclusion, octogenarians are less likely to be offered treatment irrespective of tumor stage or comorbidities. Although octogenarians have higher early mortality and poorer overall survival compared to younger patients, outcomes may be improved when treatment is performed at academic centers. Multimodality treatment did not seem to confer a survival advantage compared to surgery alone in octogenarians, and more prospective studies are necessary to better elucidate the optimal treatment in this patient population.
Sampling inequalities for anisotropic tensor product grids
Authors: Rieger Christian , Wendland Holger 
Published: December 2018

AbstractWe derive sampling inequalities for discrete point sets that are of anisotropic tensor product form. Such sampling inequalities can be used to prove convergence for arbitrary stable reconstruction processes. As usual in the context of high-dimensional problems, our sampling inequalities are expressed in terms of the number of data sites, i.e., the number of points in the sparse grid. To this end, new bounds on specific monotone sets and on the number of points in an anisotropic sparse grid are derived.
Comparative Transcriptomics Reveals Patterns of Adaptive Evolution Associated with Depth and Age Within Marine Rockfishes (Sebastes)
Authors: Heras Joseph , Aguilar Andres 
Published: December 2018

AbstractThe genetic underpinnings that contribute to ecological adaptation and speciation are not completely understood, especially within marine ecosystems. These evolutionary processes can be elucidated by studying adaptive radiations, because they provide replicates of divergence within a given environment or time-frame. Marine rockfishes (genus Sebastes) are an adaptive radiation and unique model system for studying adaptive evolution in the marine realm. We investigated molecular evolution associated with ecological (depth) and life history (lifespan) divergence in 2 closely related clades of Sebastes. Brain transcriptomes were sequenced via RNA-Seq from 3 species within the subgenus Pteropodus and a pair of related congeners from the subgenus Sebastosomus in order to identify patterns of adaptive evolution. De novo assemblies from these transcriptomes were used to identify 3867 orthologous clusters, and genes subject to positive selection were identified based on all 5 species, depth, and lifespan. Within all our analyses, we identified hemoglobin subunit α to be under strong positive selection and is associated with the depth of occurrence. In our lifespan analysis we identified immune function genes under positive selection in association with maximum lifespan. This study provides insight on the molecular evolution of rockfishes and these candidate genes may provide a better understanding of how these subgenera radiated within the Northeast Pacific.
Geometrical compression: a new method to enhance the BOSS galaxy bispectrum monopole constraints
Authors: Gualdi Davide , Gil-Marín Héctor , Manera Marc , Joachimi Benjamin , Lahav Ofer 
Published: December 2018

ABSTRACT
We present a novel method to compress galaxy clustering three-point statistics and apply it to redshift space galaxy bispectrum monopole measurements from BOSS DR12 CMASS data considering a k-space range of $0.03-0.12\, h/\mathrm{Mpc}$. The method consists in binning together bispectra evaluated at sets of wavenumbers forming closed triangles with similar geometrical properties: the area, the cosine of the largest angle, and the ratio between the cosines of the remaining two angles. This enables us to increase the number of bispectrum measurements, for example by a factor of 23 over the standard binning (from 116 to 2734 triangles used), which is otherwise limited by the number of mock catalogues available to estimate the covariance matrix needed to derive parameter constraints. The $68{{\ \rm per\ cent}}$ credible intervals for the inferred parameters (b1, b2, f, σ8) are thus reduced by $\left(-39{{\ \rm per\ cent}},-49{{\ \rm per\ cent}},-29{{\ \rm per\ cent}},-22{{\ \rm per\ cent}}\right)$, respectively. We find very good agreement with the posteriors recently obtained by alternative maximal compression methods. This new method does not require the a-priori computation of the data vector covariance matrix and has the potential to be directly applicable to other three-point statistics (e.g. galaxy clustering, weak gravitational lensing, 21-cm emission line) measured from future surveys such as DESI, Euclid, PFS, and SKA.
Radiative shocks in disk accretion
Authors: Fukue Jun 
Published: December 2018

Abstract
Radiative shock waves standing in disk accretion flows are examined under the equilibrium diffusion approximation (1T limit) in the optically thick case, taking into account the hydrostatic equilibrium in the vertical direction. In contrast to the usual one-dimensional shock, where the gas density of the post-shock region increases due to the shock compression, if the shock is sufficiently strong, the gas density in the post-shock region often decreases due to the vertical expansion behind the shock front. However, the surface density behaves like the gas density in the usual shocks, and increases up to 7 in the radiation pressure dominated shock. Hence, the vertical optical depth in the post-shock region rises, in spite of the reduction of the gas density. In addition, similar to the usual radiative shock, there appears a radiative precursor in the pre-shock region before the shock front, due to the radiative diffusion effect. We derive the overall jump conditions for the radiative shock in disk accretion flows, and solve the structure of the radiative precursor for both the gas and radiation pressure dominated cases. The solutions are quite fundamental in disk-accretion shock problems, and should be developed in various aspects.
Influenza virus and atherosclerosis
Authors: Peretz A , Azrad M , Blum A 
Published: December 2018

AbstractInfluenza viruses infect the upper respiratory system, causing usually a self-limited disease with mild respiratory symptoms. Acute lung injury, pulmonary microvascular leakage and cardiovascular collapse may occur in severe cases, usually in the elderly or in immunocompromised patients. Acute lung injury is a syndrome associated with pulmonary oedema, hypoxaemia and respiratory failure. Influenza virus primarily binds to the epithelium, interfering with the epithelial sodium channel function. However, the main clinical devastating effects are caused by endothelial dysfunction, thought to be the main mechanism leading to pulmonary oedema, respiratory failure and cardiovascular collapse. A significant association was found between influenza infection and acute myocardial infarction (AMI). The incidence of admission due to AMI during an acute viral infection was six times as high during the 7 days after laboratory confirmation of influenza infection as during the control interval (10-fold in influenza B, 5-fold in influenza A, 3.5-fold in respiratory syncytial virus and 2.7-fold for all other viruses). Our review will focus on the mechanisms responsible for endothelial dysfunction during influenza infection leading to cardiovascular collapse and death.
A Rare Case of Gender Parity in Academia
Authors: Lynn Freda B , Noonan Mary C , Sauder Michael , Andersson Matthew A 
Published: December 2018

AbstractIn academia, women trail men in nearly every major professional reward, such as earnings, publications, and funding. Bibliometric studies, however, suggest that citations are unique with regard to gender inequality: female penalties have been reported, but gender parity or even female premiums are routinely documented as well. Two questions follow from this puzzle. First, does gender matter for citations in sociology and neighboring social science disciplines? No theoretically informed study of gender and citations exists for the social science core. We begin to fill this gap by analyzing roughly 10,000 publications in economics, political science, and sociology. In contrast to many big data studies, we estimate the effect of author gender on citations alongside other author-, article-, journal-, and (sub)field-level predictors. Our results strongly suggest that when male and female authors publish articles that are comparably positioned to receive citations, their publications do in fact accrue citations at the same rate. This finding raises a second question: Why would gender matter “everywhere but here”? We hypothesize that the answer is related to the mechanisms (e.g., self-selection, biased assessments of commitment) that are activated in the context of some professional rewards but not citations. We discuss why a null gender finding should not be discarded as an anomaly but rather approached as an analytical opportunity.
Shifting Strategies: Using Film to Improve Therapeutic Communication and Nursing Education
Authors: Moosvi Karen , Garbutt Susan 
Published: December 2018

Abstract
Narrative pedagogy successfully transformed a previously discordant mental health clinical rotation into a reflective and engaged learning process. Use of the film “Wit” early in the clinical semester was popular with subsequent cohorts of students and helped better engage them in practicing therapeutic communication techniques. This article is an exemplar of the application of narrative pedagogy as a means of embracing the phenomenon of therapeutic communication in health care.