bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arousing emoticons edit stream/bounce perception of objects moving past each other
Authors: Gobara Akihiko , Yoshimura Naoto , Yamada Yuki 
Published: April 2018

AbstractWhen two identical objects move toward each other, overlap completely, and continue toward opposite ends of a space, observers might perceive them as streaming through or bouncing off each other. This phenomenon is known as ‘stream/bounce perception’. In this study, we investigated the effect of the presentation of emoticons on stream/bounce perception in five experiments. In Experiment 1, we used emoticons representing anger (‘(‘∧’)’), a smile (‘(^_^)’), and a sober face (‘(°_°)’, as a control), and observers were asked to judge whether two objects unrelated to the emoticon had streamed through or bounced off each other. The anger emoticon biased perception toward bouncing when compared with the smile or sober face emoticon. In Experiments 2 and 3, we controlled for the valence and arousal of emoticons, and found that arousal influenced stream/bounce perception but valence did not. Experiments 4 and 5 ruled out the possibility of attentional capture and response bias for the emoticon with higher arousal. Taken together, the findings indicate that emoticons with higher arousal evoke a mental image of a ‘collision’ in observers, thereby eliciting the bounce perception.
Low-intensity repetitive transcranial magnetic stimulation requires concurrent visual system activity to modulate visual evoked potentials in adult mice
Authors: Makowiecki Kalina , Garrett Andrew , Harvey Alan R. , Rodger Jennifer 
Published: April 2018

AbstractRepetitive transcranial stimulation (rTMS) is an increasingly popular method to non-invasively modulate cortical excitability in research and clinical settings. During rTMS, low-intensity magnetic fields reach areas perifocal to the target brain region, however, effects of these low-intensity (LI-) fields and how they interact with ongoing neural activity remains poorly defined. We evaluated whether coordinated neural activity during electromagnetic stimulation alters LI-rTMS effects on cortical excitability by comparing visually evoked potentials (VEP) and densities of parvalbumin-expressing (PV+) GABAergic interneurons in adult mouse visual cortex after LI-rTMS under different conditions: LI-rTMS applied during visually evoked (strong, coordinated) activity or in darkness (weak, spontaneous activity).We also compared response to LI-rTMS in wildtype and ephrin-A2A5−/− mice, which have visuotopic anomalies thought to disrupt coherence of visually-evoked cortical activity. Demonstrating that LI-rTMS effects in V1 require concurrent sensory-evoked activity, LI-rTMS delivered during visually-evoked activity increased PV+ immunoreactivity in both genotypes; however, VEP peak amplitudes changed only in wildtypes, consistent with intracortical disinhibition. We show, for the first time, that neural activity and the degree of coordination in cortical population activity interact with LI-rTMS to alter excitability in a context-dependent manner.
Association between hedonic hunger and body-mass index versus obesity status
Authors: Ribeiro Gabriela , Camacho Marta , Santos Osvaldo , Pontes Cristina , Torres Sandra , Oliveira-Maia Albino J. 
Published: April 2018

AbstractObesity-associated differences in hedonic hunger, while consistently reported, have not been adequately quantified, with most studies failing to demonstrate strong correlations between Body Mass Index (BMI) and hedonic hunger indicators. Here, we quantified and assessed the nature of the relationship between hedonic hunger and BMI, in a cross-sectional study using the Portuguese version of the PFS (P-PFS) to measure hedonic hunger. Data were collected from 1266 participants belonging to non-clinical, clinical (candidates for weight-loss surgery) and population samples. Across samples, significant but weak positive associations were found between P-PFS scores and BMI, in adjusted linear regression models. However, in logistic regression models of data from the clinical and non-clinical samples, the P-PFS Food Available domain score was significantly and robustly associated with belonging to the clinical sample (OR = 1.8, 95%CI: 1.2–2.8; p = 0.008), while in the population sample it was associated to being obese (OR = 2.1, 95%CI: 1.6–2.7; p < 0.001). Thus, hedonic hunger levels are associated with obesity status with the odds of being obese approximately doubling for each unit increase in the P-PFS Food Available score.
High-resolution behavioral mapping of electric fishes in Amazonian habitats
Authors: Madhav Manu S. , Jayakumar Ravikrishnan P. , Demir Alican , Stamper Sarah A. , Fortune Eric S. , Cowan Noah J. 
Published: April 2018

AbstractThe study of animal behavior has been revolutionized by sophisticated methodologies that identify and track individuals in video recordings. Video recording of behavior, however, is challenging for many species and habitats including fishes that live in turbid water. Here we present a methodology for identifying and localizing weakly electric fishes on the centimeter scale with subsecond temporal resolution based solely on the electric signals generated by each individual. These signals are recorded with a grid of electrodes and analyzed using a two-part algorithm that identifies the signals from each individual fish and then estimates the position and orientation of each fish using Bayesian inference. Interestingly, because this system involves eavesdropping on electrocommunication signals, it permits monitoring of complex social and physical interactions in the wild. This approach has potential for large-scale non-invasive monitoring of aquatic habitats in the Amazon basin and other tropical freshwater systems.
Dietary supplementation with flaxseed meal and oat hulls modulates intestinal histomorphometric characteristics, digesta- and mucosa-associated microbiota in pigs
Authors: Ndou S. P. , Tun H. M. , Kiarie E. , Walsh M. C. , Khafipour E. , Nyachoti C. M. 
Published: April 2018

AbstractThe establishment of a healthy gastrointestinal milieu may not only offer an opportunity to reduce swine production costs but could also open the way for a lifetime of human health improvement. This study investigates the effects of feeding soluble fibre from flaxseed meal-containing diet (FM) and insoluble fibre from oat hulls-containing diet (OH) on histomorphological characteristics, digesta- and mucosa-associated microbiota and their associations with metabolites in pig intestines. In comparison with the control (CON) and OH diets, the consumption of FM increased (P < 0.001) the jejunal villi height (VH) and the ratio of VH to crypt depths. The PERMANOVA analyses showed distinct (P < 0.05) microbial communities in ileal digesta and mucosa, and caecal mucosa in CON and FM-diets fed pigs compared to the OH diet-fed pigs. The predicted functional metagenomes indicated that amino acids and butanoate metabolism, lysine degradation, bile acids biosynthesis, and apoptosis were selectively enhanced at more than 2.2 log-folds in intestinal microbiota of pigs fed the FM diet. Taken together, flaxseed meal and oat hulls supplementation in growing pigs’ diets altered the gastrointestinal development, as well as the composition and function of microbial communities, depending on the intestinal segment and physicochemical property of the dietary fibre source.
Neurofibromin knockdown in glioma cell lines is associated with changes in cytokine and chemokine secretion in vitro
Authors: Wood Matthew D. , Mukherjee Joydeep , Pieper Russell O. 
Published: April 2018

AbstractThe neurofibromin-1 tumor suppressor gene (NF1) is altered in approximately 20% of sporadic glioblastoma (GBM) cases. NF1 deficient GBM frequently shows a mesenchymal gene expression signature, suggesting a relationship between NF1 status and the tumor microenvironment. To identify changes in the production of secreted cytokines/chemokines in NF1 deficient glioma, we applied cytokine arrays to conditioned media from a panel of three GBM cell lines after siRNA-mediated NF1 knockdown. We identified increased secretion of platelet-derived growth factor AA (PDGF-AA), chitinase-3-like protein 1 (CHI3L1), interleukin-8 (IL-8), and endoglin (ENG) in different subsets of these cell lines. Secretion was associated with induction of the corresponding messenger RNA, suggesting a mechanism involving transcriptional upregulation. By contrast, in non-transformed immortalized normal human astrocytes, PDGF-AA secretion was increased upon NF1 knockdown, while secreted CHI3L1, ENG, and IL-8 were reduced or unchanged. Analysis of The Cancer Genome Atlas confirmed a relationship between glioma NF1 status and ENG and CHI3L1 in tumor samples. Overall, this study identifies candidate changes in secreted proteins from NF1 deficient glioma cells that could influence the tumor microenvironment, and suggests a direct link between NF1 loss and increased tumor cell production of CHI3L1 and endoglin, two factors implicated in mesenchymal identity in glioblastoma.
Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background
Authors: Ghimire Sabitri , Van der Jeught Margot , Neupane Jitesh , Roost Matthias S. , Anckaert Jasper , Popovic Mina , Van Nieuwerburgh Filip , Mestdagh Pieter , Vandesompele Jo , Deforce Dieter , Menten Björn , Chuva de Sousa Lopes Susana , De Sutter Petra , Heindryckx Björn 
Published: April 2018

AbstractMouse embryonic stem cells (mESCs) exist in a naive, primed and ground state of pluripotency. While comparative analyses of these pluripotency states have been reported, the mESCs utilized originated from various genetic backgrounds and were derived in different laboratories. mESC derivation in conventional LIF + serum culture conditions is strain dependent, with different genetic backgrounds potentially affecting subsequent stem cell characteristics. In the present study, we performed a comprehensive characterization of naive, primed and ground state mESCs originating from the same genetic background within our laboratory, by comparing their transcriptional profiles. We showed unique transcriptional profiles for naive, primed and ground state mESCs. While naive and ground state mESCs have more similar but not identical profiles, primed state mESCs show a very distinct profile. We further demonstrate that the differentiation propensity of mESCs to specific germ layers is highly dependent on their respective state of pluripotency.
A Novel Lubricant Based on Covalent Functionalized Graphene Oxide Quantum Dots
Authors: Wolk Andreas , Rosenthal Marta , Neuhaus Stephan , Huber Klaus , Brassat Katharina , Lindner Jörg K. N. , Grothe Richard , Grundmeier Guido , Bremser Wolfgang , Wilhelm René 
Published: April 2018

AbstractDodecyl amine edge functionalized few-layer graphene oxide quantum dots were synthesized in good yields. The covalent functionalization was demonstrated with NMR and AFM-IR. The resulting structure and particle size was measured with AFM and HRTEM. The thermal stability of the compound was investigated and showed a stability of up to 220 °C. The modified graphene oxide quantum dots showed excellent solubility in various organic solvents, including ethers, methanol, toluene, n-hexane, heptane, xylene, dichloromethane and toluene. The stability of a resulting toluene solution was also proven by static light scattering measurements over several days. The excellent solubility gives the possibility of an efficient and fast spray application of the functionalized graphene oxide quantum dots to steel surfaces. Hence, the macroscopic friction behavior was investigated with a Thwing-Albert FP-2250 friction tester. A thin film of the dodecyl amine functionalized graphene oxide quantum dots on steel lowered the friction coefficient from 0.17 to 0.11 and revealed a significant corrosion inhibition effect.
Synthesis of Au@polymer nanohybrids with transited core-shell morphology from concentric to eccentric Emoji-N or Janus nanoparticles
Authors: Guarrotxena Nekane , García Olga , Quijada-Garrido Isabel 
Published: April 2018

AbstractThe combination of multifunctionality and synergestic effect displayed by hybrid nanoparticles (NPs) has been revealed as an effective stratagem in the development of advanced nanostructures with unique biotechnology and optoelectronic applications. Although important work has been devoted, the demand of facile, versatile and efficient synthetic approach remains still challenging. Herein, we report a feasible and innovative way for polymer-shell assembling onto gold nanoparticles in competitive conditions of hydrophobic/hydrophilic feature and interfacial energy of components to generate core-shell nanohybrids with singular morphologies. The fine control of reaction parameters allows a modulated transformation from concentric to eccentric nanostructure-geometries. In this regard, a rational selection of the components and solvent ratio guarantee the reproducibility and efficiency on hybrid-nanoassembly. Furthermore, the simplicity of the synthetic approach offers the possibility to obtain asymmetric Janus NPs and new morphologies (quizzical-aspheric polymer-shell, named Emoji-N-hybrids) with adjustable surface-coating, leading to new properties and applications that are unavailable to their symmetrical or single components.
Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia
Authors: Jahn Hannah M. , Kasakow Carmen V. , Helfer Andreas , Michely Julian , Verkhratsky Alexei , Maurer Hans H. , Scheller Anja , Kirchhoff Frank 
Published: April 2018

AbstractInducible DNA recombination of floxed alleles in vivo by liver metabolites of tamoxifen (TAM) is an important tool to study gene functions. Here, we describe protocols for optimal DNA recombination in astrocytes, based on the GLAST-CreERT2/loxP system. In addition, we demonstrate that quantification of genomic recombination allows to determine the proportion of cell types in various brain regions. We analyzed the presence and clearance of TAM and its metabolites (N-desmethyl-tamoxifen, 4-hydroxytamoxifen and endoxifen) in brain and serum of mice by liquid chromatographic-high resolution-tandem mass spectrometry (LC-HR-MS/MS) and assessed optimal injection protocols by quantitative RT-PCR of several floxed target genes (p2ry1, gria1, gabbr1 and Rosa26-tdTomato locus). Maximal recombination could be achieved in cortex and cerebellum by single daily injections for five and three consecutive days, respectively. Furthermore, quantifying the loss of floxed alleles predicted the percentage of GLAST-positive cells (astroglia) per brain region. We found that astrocytes contributed 20 to 30% of the total cell number in cortex, hippocampus, brainstem and optic nerve, while in the cerebellum Bergmann glia, velate astrocytes and white matter astrocytes accounted only for 8% of all cells.
Metabarcoding analysis of strongylid nematode diversity in two sympatric primate species
Authors: Pafčo Barbora , Čížková Dagmar , Kreisinger Jakub , Hasegawa Hideo , Vallo Peter , Shutt Kathryn , Todd Angelique , Petrželková Klára J. , Modrý David 
Published: April 2018

AbstractStrongylid nematodes in large terrestrial herbivores such as great apes, equids, elephants, and humans tend to occur in complex communities. However, identification of all species within strongylid communities using traditional methods based on coproscopy or single nematode amplification and sequencing is virtually impossible. High-throughput sequencing (HTS) technologies provide opportunities to generate large amounts of sequence data and enable analyses of samples containing a mixture of DNA from multiple species/genotypes. We designed and tested an HTS approach for strain-level identification of gastrointestinal strongylids using ITS-2 metabarcoding at the MiSeq Illumina platform in samples from two free-ranging non-human primate species inhabiting the same environment, but differing significantly in their host traits and ecology. Although we observed overlapping of particular haplotypes, overall the studied primate species differed in their strongylid nematode community composition. Using HTS, we revealed hidden diversity in the strongylid nematode communities in non-human primates, more than one haplotype was found in more than 90% of samples and coinfections of more than one putative species occurred in 80% of samples. In conclusion, the HTS approach on strongylid nematodes, preferably using fecal samples, represents a time and cost-efficient way of studying strongylid communities and provides a resolution superior to traditional approaches.
Overwintering of West Nile virus in a bird community with a communal crow roost
Authors: Montecino-Latorre Diego , Barker Christopher M. 
Published: April 2018

AbstractIn temperate climates, transmission of West Nile virus (WNV) is detectable rarely during the coldest months (late fall through early spring), yet the virus has reappeared consistently during the next warm season. Several mechanisms may contribute to WNV persistence through winter, including bird-to-bird transmission among highly viremic species. Here we consider whether, under realistic scenarios supported by field and laboratory evidence, a winter bird community could sustain WNV through the winter in the absence of mosquitoes. With this purpose we constructed a deterministic model for a community of susceptible birds consisting of communally roosting crows, raptors and other birds. We simulated WNV introduction and subsequent transmission dynamics during the winter under realistic initial conditions and model parameterizations, including plausible contact rates for roosting crows. Model results were used to determine whether the bird community could yield realistic outbreaks that would result in WNV infectious individuals at the end of the winter, which would set up the potential for onward horizontal transmission into summer. Our findings strongly suggest that winter crow roosts could allow for WNV persistence through the winter, and our model results provide synthesis to explain inconclusive results from field studies on WNV overwintering in crow roosts.
Application of iron-loaded activated carbon electrodes for electrokinetic remediation of chromium-contaminated soil in a three-dimensional electrode system
Authors: Yan Yujie , Xue Fengjiao , Muhammad Faheem , Yu Lin , Xu Feng , Jiao Binquan , Shiau YanChyuan , Li Dongwei 
Published: April 2018

AbstractHexavalent chromium from industrial residues is highly mobile in soil and can lead to the contamination of groundwater through runoff and leaching after rainfall. This paper focuses on the three-dimensional (3D) electrokinetic remediation (EKR) of chromium-contaminated soil from an industrial site. Activated carbon particles coupled with Fe ions (AC-Fe) were used as the third electrode. The optimum dose ratio of the electrode particles and remediation time were selected on the basis of single-factor experiments. X-ray photoelectron spectroscopy (XPS) analysis was carried out to explore the reduction of Cr(VI) on the surface of the electrode particles (AC-Fe). The results showed that AC-Fe had a positive effect on Cr(VI) reduction with a removal rate of 80.2%, which was achieved after 10 d by using a 5% dose of electrode particles. Finally, it was concluded that the removal mechanism combined the processes of electromigration, electrosorption/adsorption and reduction of Cr(VI) in the 3D EKR system.
Possible superconductivity in the Bismuth IV solid phase under pressure
Authors: Valladares Ariel A. , Rodríguez Isaías , Hinojosa-Romero David , Valladares Alexander , Valladares Renela M. 
Published: April 2018

AbstractThe first successful theory of superconductivity was the one proposed by Bardeen, Cooper and Schrieffer in 1957. This breakthrough fostered a remarkable growth of the field that propitiated progress and questionings, generating alternative theories to explain specific phenomena. For example, it has been argued that Bismuth, being a semimetal with a low number of carriers, does not comply with the basic hypotheses underlying BCS and therefore a different approach should be considered. Nevertheless, in 2016 based on BCS we put forth a prediction that Bi at ambient pressure becomes a superconductor at 1.3 mK. A year later an experimental group corroborated that in fact Bi is a superconductor with a transition temperature of 0.53 mK, a result that eluded previous work. So, since Bi is superconductive in almost all the different structures and phases, the question is why Bi-IV has been elusive and has not been found yet to superconduct? Here we present a study of the electronic and vibrational properties of Bi-IV and infer its possible superconductivity using a BCS approach. We predict that if the Bi-IV phase structure were cooled down to liquid helium temperatures it would also superconduct at a T
c
of 4.25 K.
Memory effect and magnetocrystalline anisotropy impact on the surface magnetic domains of magnetite(001)
Authors: Martín-García Laura , Chen Gong , Montaña Yaiza , Mascaraque Arantzazu , Pabón Beatriz M. , Schmid Andreas K. , de la Figuera Juan 
Published: April 2018

AbstractThe structure of magnetic domains, i.e. regions of uniform magnetization separated by domain walls, depends on the balance of competing interactions present in ferromagnetic (or ferrimagnetic) materials. When these interactions change then domain configurations also change as a result. Magnetite provides a good test bench to study these effects, as its magnetocrystalline anisotropy varies significantly with temperature. Using spin-polarized electron microscopy to map the micromagnetic domain structure in the (001) surface of a macroscopic magnetite crystal (~1 cm size) shows complex domain patterns with characteristic length-scales in the micrometer range and highly temperature dependent domain geometries. Although heating above the Curie temperature erases the domain patterns completely, cooling down reproduces domain patterns not only in terms of general characteristics: instead, complex microscopic domain geometries are reproduced in almost perfect fidelity between heating cycles. A possible explanation of the origin of the high-fidelity reproducibility is suggested to be a combination of the presence of hematite inclusions that lock bulk domains, together with the strong effect of the first order magnetocrystalline anisotropy which competes with the shape anisotropy to give rise to the observed complex patterns.
Potential formula of the nonregular m × n fan network and its application
Authors: Tan Zhen , Tan Zhi-Zhong , Chen Jianxin 
Published: April 2018

AbstractPotential formula of an arbitrary resistor network has been an unsolved problem for hundreds of years, which is an interdisciplinary problem that involves many areas of natural science. A new progress has been made in this paper, which discovered the potential formula of a nonregular m × n fan network with two arbitrary boundaries by the Recursion-Transform method with potential parameters (simply call RT-V). The nonregular m × n fan network is a multipurpose network contains several different types of network model such as the interesting snail network and hart network. In the meantime, we discussed the semi-infinite fan network and a series of novel and special conclusions are produced, the effective resistance is educed naturally. The discovery of potential formulae of resistor network provides new theoretical tools and techniques for related scientific research.