bluuebunny/crossref_metadata_2025_split huggingface dataset:
Light emission from the Fe2+–EDTA–ascorbic acid–H2O2 system strongly enhanced by plant phenolic acids
Authors: Nowak Michal , Tryniszewski Wiesław , Sarniak Agata , Włodarczyk Anna , Nowak Piotr J. , Nowak Dariusz 
Published: January 2019

AbstractOxidative reactions can result in the formation of electronically excited species that undergo radiative decay depending on electronic transition from the excited state to the ground state with subsequent ultra‐weak photon emission (UPE). We investigated the UPE from the Fe2+–EDTA (ethylenediaminetetraacetic acid)–AA (ascorbic acid)–H2O2 (hydrogen peroxide) system with a multitube luminometer (Peltier‐cooled photon counter, spectral range 380–630 nm). The UPE, of 92.6 μmol/L Fe2+, 185.2 μmol/L EDTA, 472 μmol/L AA, 2.6 mmol/L H2O2, reached 1217 ± 118 relative light units during 2 min measurement and was about two times higher (P < 0.001) than the UPE of incomplete systems (Fe2+–AA–H2O2, Fe2+–EDTA–H2O2, AA–H2O2) and medium alone. Substitution of Fe2+ with Cr2+, Co2+, Mn2+ or Cu2+ as well as of EDTA with EGTA (ethylene glycol‐bis(β‐aminoethyl ether)‐N,N,N′,N′‐tetraacetic acid) or citrate powerfully inhibited UPE. Experiments with scavengers of reactive oxygen species (dimethyl sulfoxide, mannitol, sodium azide, superoxide dismutase) revealed the dependence of UPE only on hydroxyl radicals. Dimethyl sulfoxide at the concentration of 0.74 mmol/L inhibited UPE by 79 ± 4%. Plant phenolics (ferulic, chlorogenic and caffec acids) at the concentration of 870 μmol/L strongly enhanced UPE by 5‐, 13.9‐ and 46.8‐times (P < 0.001), respectively. It is suggested that augmentation of UPE from Fe2+–EDTA–AA–H2O2 system can be applied for detection of these phytochemicals.
Buprofezin dissipation and safety assessment in open field cabbage and cauliflower using GC/ITMS employing an analyte protectant
Authors: Abdallah Osama , El Agamy Moustafa , Abdelraheem Ehab , Malhat Farag 
Published: January 2019

AbstractAn analytical method for the determination of buprofezin residues in cabbage and cauliflower was developed and validated using gas chromatography with ion trap mass spectrometry. The analyte protectant d‐sorbitol was used at a concentration level of 0.5 mg mL−1 in acetonitrile instead of in matrix for constructing the calibration curves of the buprofezin standard. The average recoveries ranged from 91.3 to 96.8%, with an RSD of ≤2.7%. The limits of detection and quantitation of the method in cabbage and cauliflower were 1.3, 1.7 and 4.3, 6.2 μg kg−1, respectively. The residual levels and dissipation kinetics of buprofezin 25% wettabe powder in cabbage and cauliflower cultivated under open field conditions was investigated at the single (T1) and double (T2) recommended rates of application. Half‐life periods were found to be 1.73 and 2.1 days in cabbage, whereas in cauliflower, these values were 1.85 and 2.36 days at T1 and T2, respectively. Based on the dissipation study, and the maximum residue limit value of 0.05 mg kg−1, the proposed pre‐harvest interval of buprofezin in cabbage was 3–6 days and that in cauliflower was 4–10 days. The results showed that buprofezin is safe for application at both recommended application rates.
Influence of Impeller Diameter on Crystal Growth Kinetics of Borax in a Mixed Dual‐Impeller Batch‐Cooling Crystallizer
Authors: Čelan Antonija , Ćosić Marija , Pehnec Igor , Kuzmanić Nenad 
Published: January 2019

AbstractThe influence of impeller diameter on crystal growth kinetics of borax decahydrate in a batch‐cooling crystallizer of non‐standard aspect ratio was evaluated. The dual‐impeller configuration consisted of a pitched‐blade turbine which was mounted below a straight‐blade turbine on a single shaft. Three different impeller‐to‐tank diameter ratios were investigated. In all experiments, mixing was conducted at just‐suspended impeller speed. To examine hydrodynamic conditions, mixing times were measured. The fluid flow pattern and velocity distribution were determined by computational fluid dynamics. Results showed that the smallest but also more regularly shaped crystals were produced in a system with standard diameter impellers. Product yield and power consumption were highest in this case.
Synthesis of Boron‐Doped Graphene by Supercritical Fluid Processing and its Application in Symmetric Supercapacitors using Various Electrolytes
Authors: Balaji S. Suresh , Karnan M. , Kamarsamam J. , Sathish M. 
Published: January 2019

AbstractDoping of heteroatoms on graphene networks is an efficient way of modifying both, chemical and electrochemical properties of graphene. Here, the preparation of boron doped graphene was achieved by supercritical fluid processing using sodium tetraborate as a boron source. The phase purity, structure and surface morphology of all the prepared materials were characterised by XRD, Raman spectra, FE‐SEM and HR‐TEM. The presence of boron bearing functionalities and type of B‐doping are determined by FT‐IR spectroscopy and XPS, respectively. From the different weight combination of B‐source along with graphene oxide, the B‐doped graphene obtained from B‐source and graphene oxide are in 1 : 2 weight ratio showed an enhanced capacitive behaviour over reduced graphene oxide with an improved specific capacitance value of 270 F/g at 1 A/g and revealed a superior cycling stability of 93 % retention over 10000 cycles at 10 A/g. To appreciate the device performance, the full cell studies was performed in three different electrolytes and the energy density obtained using 1‐ethyl‐3‐methyl imidazolium tetrafluoroborate (EMIMBF4) as ionic liquid electrolyte is found to be 39.3 Wh/kg which is higher than both 20 % KOH solution (5.1 Wh/kg) and 1 M TEABF4 in acetonitrile (18.6 Wh/kg).
Laboratory measurements of solubility and swelling factor for CO2/Brine and CO2/heavy oil binary systems under low‐medium pressure and temperature
Authors: Jamshidi Tayebeh , Zeng Fanhua , Tontiwachwuthikul Paitoon , Torabi Farshid 
Published: January 2019

AbstractAn extensive experimental study was performed to investigate the effect of various parameters such as temperature, pressure, and crude oil API gravity on the fluid interactions in the binary systems of brine‐CO2 and two heavy oil‐CO2 systems. The solubility of CO2 in 20 000 ppm brine solution was measured at various experimental conditions. The solubility of CO2 and swelling factor, due to the CO2 dissolution, of two heavy crude oil samples (type‐I: °API = 20.44 and type‐II: °API = 15.49) were experimentally measured at various operating conditions.Results showed that the solubility of CO2 in heavy oil increased when the experimental pressure increased, and when the experimental temperature decreased. At a constant pressure of Pexp = 3.44 MPa, the solubility of the CO2 was measured to be 10.13, 5.72 g CO2/100 g oil in the type‐I crude oil when the temperature increased from T = 21 to 45 °C. Increasing the experimental pressure from Pexp = 1.38 MPa to 3.44 MPa at a constant temperature of T = 21 °C increased the solubility of the CO2 from 2.37 to 7.84 g CO2/100 g oil in the type‐II crude oil. The reduction in the oil API gravity had an adverse effect on the CO2 solubility. At a temperature of T = 21 °C and a pressure of Pexp = 3.44 MPa, the CO2 solubility decreased from ∼10.13 in the type‐I oil to 7.84 g CO2/100 g oil in the type‐II oil. The measured values of the swelling factor showed that the type‐I and type‐II crude oils could exhibit a maximum swelling factor of 1.079 and 1.052 at a temperature of T = 21 °C and a pressure of Pexp = 3.44 MPa.
Synthesis, Structures and Properties of C(sp2)‐Centered Homo‐ and Hetero‐Nuclear Gold Complexes
Authors: Li Cui‐Cui , Zhao Liang 
Published: January 2019

AbstractC(sp2)‐centered homo‐ and hetero‐nuclear gold complexes have attracted widespread interests in recent decades. Studies of this type of complexes may deepen the understandings of the intermediates in Au‐catalyzed organic reactions and explore new applications in catalytic and material science. The focuses of this review include the synthesis, structural characteristics, properties and applications of C(sp2)‐centered homo‐ and hetero‐nuclear gold complexes according to different structural classifications.
Pseudo[n,m]rotaxanes of Cucurbit[7/8]uril and Viologen‐Naphthalene Derivative: A Precise Definition of Rotaxane
Authors: Zhang Beilin , Dong Yunhong , Li Jie , Yu Yang , Li Chenyang , Cao Liping 
Published: January 2019

Summary of main observation and conclusionRotaxane is a kind of classic supramolecule, which is usually constructed from a number of macrocycles and one axis molecule. Herein, we have expanded the supramolecular structure of [n]rotaxane to offer a precise definition of (pseudo)[n,m]rotaxane for accurately describing the two kinds of (pseudo)rotaxanes structures, which are self‐assembled from cucurbit[7/8]uril (CB[7/8]) and viologen‐naphthalene derivative, respectively. Furthermore, these CB‐based pseudorotaxanes exhibit varied photophysical properties, stimuli‐responsive behavior triggered by competitive guest, and self‐sorting behavior.
Multivariate association test for rare variants controlling for cryptic and family relatedness
Authors: Sun Jianping , Oualkacha Karim , Greenwood Celia M.T. , Lakhal‐Chaieb Lajmi 
Published: January 2019

AbstractIn genetic studies of complex diseases, multiple measures of related phenotypes are often collected. Jointly analyzing these phenotypes may improve statistical power to detect sets of rare variants affecting multiple traits. In this work, we consider association testing between a set of rare variants and multiple phenotypes in family‐based designs. We use a mixed linear model to express the correlations among the phenotypes and between related individuals. Given the many sources of correlations in this situation, deriving an appropriate test statistic is not straightforward. We derive a vector of score statistics, whose joint distribution is approximated using a copula. This allows us to have closed‐form expressions for the p‐values of several test statistics. A comprehensive simulation study and an application to Genetic Analysis Workshop 18 data highlight the gains associated with joint testing over univariate approaches, especially in the presence of pleiotropy or highly correlated phenotypes. The Canadian Journal of Statistics 47: 90–107; 2019 © 2018 Statistical Society of Canada
Negative predictive value and sensitivity of urine cytology prior to implementation of The Paris System for Reporting Urinary Cytology
Authors: McIntire Patrick J. , Khan Reema , Hussain Hamad , Pambuccian Stefan E. , Wojcik Eva M. , Barkan Güliz A. 
Published: January 2019

BackgroundUrinary tract cytology (UTCy) is used for screening urothelial carcinoma (UC) and it must have a high negative predictive value (NPV) to be an effective test. To the authors’ knowledge, the literature regarding the NPV of UTCy provides little information regarding the risk of malignancy, especially for patients with high‐grade urothelial carcinoma (HGUC).MethodsPatients with negative UTCy specimens were identified in the pathology files at the study institution for the years 2012 through 2013. Cases were deemed true‐negative cases if there was at least 1 subsequent negative specimen or negative clinical follow‐up within 6 months of the index case. False‐negative cases were defined as HGUC or carcinoma in situ by surgical biopsy and/or any UTCy with suspicious for HGUC or HGUC follow‐up.ResultsA total of 2614 UTCy specimens from 2089 patients were identified. There was a disease prevalence of 6.5%. There were 87 false‐negative results for HGUC, which corresponded to an overall NPV of 96.7%. When categorized by clinical indication, hematuria resulted in the highest NPV of 99.5% followed by other indications (97.7%) and a history of UC (90.1%). When categorized by the specimen type, voided urine specimens were found to have the highest NPV of 98.7% followed by other indications (96.9%) and washing specimens (96.2%). Of the 717 patients with a history of UC, the NPV was lower for washing specimens (89.8%) than for voided urine specimens (96.2%). When including either low‐grade urothelial carcinoma or HGUC as a positive follow‐up, the NPV dropped to 93.3% from 96.7% (HGUC only). The sensitivity of the diagnostic category of atypical urothelial cells or higher was 93.0%.ConclusionsOverall, UTCy appears to have a good NPV and a high sensitivity for HGUC. The clinical indication had a greater impact on NPV compared with the specimen type.
An investigation into the impact of daylight on perceived color of façade: Understanding the role of chromaticness
Authors: Asarzadeh Karim , Madani Ramin , Nilforoushan Mohammad Reza , Mahyar Forough 
Published: January 2019

AbstractColor selection has always been a classic problem in exterior color design for the simple reason that façade color is commonly chosen at the architect's office, regardless of different external conditions affecting color perception. This issue often leads to an apparent discrepancy between the selected color and the perceived color of façade. So far, extensive research has been carried out to identify, classify, and study the influence of these conditions on perceived color. However, little attention has been paid to the importance of color attributes. Hence, this article attempts to grasp better the significance of chromaticness, as briefly discussed in earlier studies, in the variation pattern of perceived color while daylight condition differs. In order to determine perceived color, each test subject was asked to compare the color seen on the façade to the standard color samples of natural color system index and choose the matching one, using a designed color‐measuring device. The results obtained from 93 participants demonstrate 3 things: First, they further support the belief that perceived color is influenced in both hue and nuance under varied daylight circumstances. Second, they confirm previous findings that indicated chromaticness would affect the extent of color shifts. And above all, a comparison of the results reveals that façade colors of higher chromaticness values have had less shifts in hue, yet greater shifts in whiteness. Finally, the findings suggest that chromaticness together with the external conditions, under which the color is to be seen, should be carefully considered when selecting the façade color.
Parallel pairwise learning to rank for collaborative filtering
Authors: Yağcı A. Murat , Aytekin Tevfik , Gürgen Fikret S. 
Published: January 2019

SummaryPairwise learning to rank is known to be suitable for a wide range of collaborative filtering applications. In this work, we show that its efficiency can be greatly improved with parallel stochastic gradient descent schemes. Accordingly, we first propose to extrapolate two such state‐of‐the‐art schemes to the pairwise learning to rank problem setting. We then show the versatility of these proposals by showing the applicability of several important extensions commonly desired in practice. Theoretical as well as extensive empirical analyses of our proposals show remarkable efficiency results for pairwise learning to rank in offline and stream learning settings.
Highly Resolved Pure‐Shift Spectra on a Compact NMR Spectrometer
Authors: Castaing‐Cordier Thomas , Bouillaud Dylan , Bowyer Paul , Gonçalves Olivier , Giraudeau Patrick , Farjon Jonathan 
Published: January 2019

AbstractBenchtop NMR spectrometers experience a great success for a wide range of applications. However, their performance is highly limited by peak overlaps. Emerging “pure‐shift NMR” (PS NMR) methods have been intensively used at high field to enhance the resolution by homodecoupling strategies. Here, different PS methods have been implemented on a compact NMR spectrometer operating at 43 MHz. Among the PS methods, the recent PSYCHE scheme appears more sensitive than Zangger‐Sterk (ZS) experiments and offers a substantial resolution improvement as compared to 1D 1H. On the other hand, despite their slightly lower sensitivity, ZS methods are more efficient to reduce broad signals and are more immune to strong couplings. Finally, the classical J‐resolved pulse sequence is more efficient to reduce larger signals for bigger‐sized molecules. The three approaches appear relevant for benchtop NMR and their combination forms an efficient toolbox to analyze a great diversity of samples.
High salivary levels of JP2 genotype of Aggregatibacter actinomycetemcomitans is associated with clinical attachment loss in Moroccan adolescents
Authors: Ennibi Oum Keltoum , Claesson Rolf , Akkaoui Sanae , Reddahi Sarah , Kwamin Francis , Haubek Dorte , Johansson Anders 
Published: January 2019

AbstractIt has previously been shown that the presence of Aggregatibacter actinomycetemcomitans in subgingival plaque is significantly associated with increased risk for clinical attachment loss. The highly leukotoxic JP2 genotype of this bacterium is frequently detected in adolescents with aggressive forms of periodontitis. The aims of the study were to quantify the levels of JP2 and non‐JP2 genotypes of A. actinomycetemcomitans in saliva of Moroccan adolescents with the JP2 genotype earlier detected in the subgingival plaque. The salivary concentrations of inflammatory proteins were quantified and linked to the clinical parameters and microbial findings. Finally, a mouth rinse with leukotoxin‐neutralizing effect was administrated and its effect on the levels the biomarkers and A. actinomycetemcomitans examined. The study population consisted of 22 adolescents that previously were found to be positive for the JP2 genotype in subgingival plaque. Periodontal registration and sampling of stimulated saliva was performed at baseline. A mouth rinse (active/placebo) was administrated, and saliva sampling repeated after 2 and 4 weeks rinse. The salivary levels of JP2 and non‐JP2 were analyzed by quantitative PCR and inflammatory proteins by ELISA. Both the JP2 and the non‐JP2 genotype were detected in all individuals with significantly higher levels of the non‐JP2. Enhanced levels of the JP2 genotype of A. actinomycetemcomitans was significantly correlated to the presence of attachment loss (≥3 mm). Salivary concentrations of inflammatory biomarkers did not correlate to periodontal condition or levels of A. actinomycetemcomitans. The use of active or placebo leukotoxin‐neutralizing mouth rinse did not significantly interfered with the levels of these biomarkers. Saliva is an excellent source for detection of A. actinomycetemcomitans on individual basis, and high levels of the JP2 genotype were significantly associated with the presence of clinical attachment loss.
Toward an Integrated Phenotype in Pre‐NIDDM
Authors: Bergman R.N. , Watanabe R. , Rebrin K. , Ader M. , Steil G. 
Published: January 2019

The search for the genetic basis of NIDDM has magnified the need for an efficient representation of the pre‐NIDDM phenotype. The overall goal is to relate specific mutations on the genome to specific changes in physiologic function which lead to NIDDM. Unfortunately, there is still not a clear understanding of the molecular cause of NI.DDM in most individuals. Therefore, one must take an alternative approach: to express in quantitative terms the various tissue processes which determine the ability to regulate the blood glucose in fasting and after carbohydrate administration. A minimal list of such processes includes the provision of glucose by the liver, insulin sensitivity, insulin secretion, and glucose effectiveness. The latter function is the ability of glucose per se to enhance glucose disappearance from blood, independent of a dynamic insulin response. Approaches to measuring the list of functions which determine the glucose tolerance are reviewed: they include the minimal model method, which quantitates insulin sensitivity (S1) and glucose effectiveness (SG) and a combined model approach, which ·measures insulin secretion. These methods are being developed for large populations. Such a development is important for elucidating the causes of reduced glucose tolerance in populations, and examining the relation between such causes and outcomes including diabetes and cardiovascular disease. Of particular importance for diabetes development is the characteristic hyperbolic relationship between insulin secretion and insulin action. This relationship, the 'hyperbolic law of glucose tolerance' indicates that insulin secretion can only be assessed in terms of the ainbient degree of insulin sensitivity. By applying this principle, it is clear that latent pancreatic islet‐cell dysfunction has been underestimated, and may be significant even in subjects with impaired glucose tolerance.Finally, new explorations of insulin control of liver glucose output indicate that this process may be under the control of free fatty acids. The latter realization indicates that the insulin effect on lipolysis is what is critical for determination of glucose output in the fasting state, and that insulin resistance at the level of the adipocyte may determine the extent of fasting hyperglycaemia, and may be an important factor.in the overall phenotype in prediabetic and NIDDM individuals.
Public Comments on the Proposed Common Rule Mandate for Single‐IRB Review of Multisite Research
Authors: Taylor Holly A. , Ehrhardt Stephan , Ervin Ann‐Margret 
Published: January 2019

ABSTRACTWe reviewed the public comments submitted in response to the Department of Health and Human Services’ (DHHS’s) original and revised proposal for mandated single‐IRB review of federally funded multisite research to see who responded to the proposed mandate and to determine what they said and how the agency addressed the public comments in its revised proposal. Our analysis indicates that support for the single‐IRB mandate was limited. The most common argument against the proposed mandate came from those concerned with the loss of site‐specific institutional review board (IRB) review of the protocol for a multisite study to address issues relevant to local context. Concerns were also raised that the single‐IRB approach would replace one inefficient system (that entails, for example, multiple reviews of a single study) with another potentially inefficient system (involving the negotiation and management of multiple interinstitutional agreements). Empirical research about the implementation of DHHS’s final rule—and the separate rule of the National Institutes of Health—mandating single‐IRB review is needed to determine whether the single‐IRB model achieves the stated goals.