bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of Entamoeba Gingivalis in Diseased and Healthy Periodontal Sites among Cancer Patients in Thi-Qar Province
Authors: Adnan Raed , Al-Aboody Bassad A. 
Published: December 2024

Periodontitis, being one of the most common illnesses in the world represents a significant public health concern. The aims of this study are to determine Entamoeba gingivalis prevalence in cancer patients compared to healthy individuals (as a control), study some of the factors (such as diabetes and smoking) affecting the presence of this parasite, in cancer patients and control in the Thi-Qar Province of Iraq. For detection of Entamoeba gingivalis samples, were collected from cancer patients (different types of cancer) and control, including individuals with and without periodontitis, from Al- Haboubi Teaching Hospital during the period from August 2023 to December 2023. The current study showed the overall infection rate of E. gingivalis was 46.33% in all study samples. The results also showed that the presence of Trophozoite and the cyst-like trophozoite of E. gingivalis was found in 7.19% of positive samples (n = 10/139). This study indicated that there are significant differences (p<0.05) in the percentage of E. gingivalis infections in individuals with periodontitis, diabetes, or smoking ; these have a higher infection rate than those who without, in both the cancer patients and control. No significant differences p<0.05 were seen in the infection rate of E. gingivalis between males and females in both groups. The results showed that the infection rate of E. gingivalis was highest in the age group ≥61 and lowest in the age group ≤30 for both cancer patients and the control group, regardless of whether they had periodontitis or not.
Isolation and identification of Klebsiella pneumonia from wound infections and study of the synergistic effect of carpenems and cefepime
Authors: Qasim Ali , Hind Abdullah Salih  
Published: December 2024

Surgical site infection (SSI) is a major source of morbidity and mortality in developing countries despite recent advances in sterile techniques. We studied antibiotics through their effect on bacterial pathogens isolated from wound infections singly and synergistically, which were observed in hospitals in Dhi Qar Governorate. These bacteria, Klebsiella pneumoniae 300 clinical samples were collected from Al-Hussein Teaching, Nasiriya Teaching and Al-Haboubi Teaching Hospitals in Dhi Qar Governorate for the period from September - December 2023. The results showed the presence of 16 bacterial isolates belonging to K. Pneumonia. Statistical and descriptive analysis was performed using chi-square. The rates of antibiotic resistance varied through the use of 4 types of carpenems and one type of cephalosporins. The resistance rate to meropenem alone was 6 (37.5%), while the resistance rate was higher for meropenem synergistically with Imipenem, Ertapenem, Doripenem, and cefepime, 7 (43.8%), respectively. In case of synergy the resistance rate was as to Imipenem, 7 (43.8) alone, while in synergy, the resistance rate was lower for Imipenem with cefepime, Ertapenem, and Doripenem, 5 (29.4%), 5 (31.3%), 6 (37.5%), respectively the resistance rate for synergy was highest than cefepime which was 11 (68.8) alone, while synergistically the resistance rate was lower for cefepime with Ertapenem and Doripenem 7 (38.9%), 7 (43.8%) respectively. While resistance to Ertapenem was higher than Doripenem 9 (56.3) and 7 (43.8), respectively, alone and synergistically, the resistance rate was lower for Ertapenem with Doripenem 5 (31.3%). This study revealed that taking two synergistic
Isolation, identification and antifungal susceptibility of Candida species in postmenopausal women
Authors: Abdul Mohsen Sally , Diyaa Abed Aljaza  
Published: December 2024

Abstract— The term "vulvovaginal candidiasis" refers to an inflammatory, non-erosive Vulvovaginitis characterized by symptoms such as itching, pain, dyspareunia, and discharge. The condition is treated with antifungal medication if a positive culture from a low vaginal swab reveals Candida. It should be mentioned that these people had ongoing medical conditions. VVC had previously been classified as acute or recurring. It appears that estrogen is a key permissive factor in VVC. Clinical findings have demonstrated that VVC is uncommon in premenopausal and postmenopausal women and that the post-menopausal vagina rarely contains isolated Candida. The study aimed to know the relationship between Vulvovaginitis and candida in postmenopausal women and effectiveness of some antifungals. A total of 100 postmenopausal women With Vulvovaginitis, aged 45 to 69, had vaginal swabs taken from them. Upon arrival at the laboratory, all samples were cultured on Sabouraud dextrose agar . The species of the isolated yeasts were identified by a variety of methods, including molecular analysis with primers ITS1–ITS4, growth on Chrom agar medium, and biochemical analyses. Result: candida in postmenopausal women is less than in per menopausal due to effectiveness of estrogen hormone in reproductive age . The outcomes On Chrom agar showed, six species of candida—C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, C. krusei, and c. rugosa—were isolated. Among the other species, C. glabrata was discovered to be the most prevalent. The findings demonstrated that four species of yeast-like fungi were identified using molecular diagnosis and genetic testing as follows:
Correlation between Insulin antibodyand HbA1c in Diabetes Mellitus
Authors: Sharad Joumana , Mousa Hind 
Published: December 2024

Insulin antibodies (INAs) are found in both types of diabetic patients and have low binding capacity and high affinity leading to hypoglycemia or hyperglycemia in type II patients taking insulin, which differs from the insulin antibodies found in type I that contain a high capacity of insulin binding and low affinity. This work aims to detect the levels of insulin antibodies and HbA1c in diabetic patients, and find the correlation between them and its potential role in glucose control. The study involved 60 patients with diabetes, divided into two groups type I and type II, each group containing 30 patients, in addition to 30 healthy individuals as a control group. High-performance liquid chromatography in a D-10 analyzer was used to measure HbA1c while ELISA was used to measure INAs in control and patients .Results: The current finding showed significant an elevated mean levels of HbA1c and INAs in both of patients groups compare to healthy, and there was non-significant weak positive correlation between them (R= 0.107 , P= 0.4 ).Together, elevated levels of HbA1c and INA, and the positive correlation between their levels, provide evidence of the effect of insulin antibodies on glycemic control and the effects of HbA1c levels in patients with diabetes.
Commercial amino acids for yield and its components of common bean Azufrado Reyna in Northern Sinaloa
Authors: Romero-Félix Celia S. , Sifuentes-Ibarra Ernesto , Buelna-Tarín Salomon , López-Valenzuela Blanca E. , Ruelas-Islas Jesús del Rosario , Almada-Ruiz Víctor G. 
Published: December 2024

Objective: To investigate the effect of foliar commercial amino acids on yield and its components of common bean Azufrado Reyna under field conditions.
Design/methodology/approach: Randomized complete block design with four replicates and four treatments (three commercial amino acids and a control). Grain yield, aboveground biomass, number of pods and normal seeds per unit surface, number of grains per pod, number of normal seeds per pod, weight of 100 seeds, and individual weight of seed were evaluated.
Results: All biostimulants influenced the increase in grain yield, aboveground biomass, number of normal pods and seeds per unit surface as well as the number of seeds per pod with respect to the control.
Limitations on study/implications: The study only assessed the evaluation of agronomic variables; therefore, it is necessary the measurement of morpho-physiological traits that provide evidence about the benefits of foliar aminoacids on yield and the formation of each component under field conditions.
Findings/conclusions: Foliar biostimulant application had a positive effect on grain yield and some of its components as compared to the control. The number of normal seeds per normal pod was the variable that showed the highest correlation with grain yield.
Membangun Personal Branding Sebagai Food Artist Dalam Konten Video
Authors: Lifani Estrelita Irine , Sekarwangi Maya , Siswanta Siswanta 
Published: December 2024

Maraknya penggunaan media sosial tiktok yang sebelumnya hanya digunakan sebagai media untuk menghibur atau merekam diri kini penggunanya menjadikan fenomena baru yang bisa meluas menjadi alat komunikasi sarana mempresentasikan diri atau makna lainnya bisa disebut Personal branding. Peneliti mengambil Salah satu dari banyaknya content kreator memasak di Indonesia yang menggunakan media sosial tiktok sebagai sarana personal branding ialah Sarah Eka Aprilia atau akrab dipanggil Sarah Aprilia .
Penelitian ini berjudul Membangun Personal branding sebagai Food Artist dalam Konten Video ( Studi pada akun tiktok @Sarahkapril) Penelitian ini merupakan penelitia metode kualitatif dengan pendekatan femenologi . Penelitian ini bertujuan untuk mengetahui Sarah Aprilia dalam membangun personal brandingnya sebagai food artist melalui konten video yang diunggahnya pada media sosial Tiktok . Dianalis menggunakan teori Peter Montoya dengan delapan konsep pembentukan personal branding .
Hasil dari penelitian ini adalah Secara keseluruhan sarah aprilia berhasil melakukan personal brandingnya sebagai food artist pada media sosial tiktoknya . Prosesnya didukung dengan berkonsisten dan fokus dengan tema konsep yang diambil juga berani kreaif berexperiment sehingga menciptakan suatu yang unik. Kemudian dengan selalu mengikuti perkembangan trend media sosial tiktok dan selalu memaksimalkan penggunaan pada fitur â€“ fitur yang pada ada media sosial tiktok juga membuat dan menampilkan ciri khasnya yang berpenampilan nyentrik.
.
Kata Kunci :Personal Branding, Konten , Tiktok
SOSIALISASI KEBIJAKAN DIGITALISASI TELEVISI
Authors: Cahyati Yantika Nur , Hastuti Nurnawati Hindra , Widyowati Estu 
Published: December 2024

Kebijakan digitalisasi televisi sebagai agenda besar dalam pembangunan nasional harus mendapat perhatian yang kuat dari semua pihak agar segera terwujud. Dalam hal ini, masyarakat Indonesia perlu mendapatkan sosialisasi agar mengerti seluk beluk digitalisasi televisi. Sejak tahun 2021, pemerintah telah melakukan sosialisasi melalui berbagai media, tetapi ketika Analog Switch Off (ASO) telah diterapkan masih banyak masyarakat yang belum beralih ke televisi digital. Oleh karena itu, peneliti tertarik melakukan penelitian tentang sosialisasi kebijakan digitalisasi televisi di Kelurahan Banaran. Penelitian ini bertujuan untuk menganalisis bagaimana pelaksanaan sosialisasi kebijakan digitalisasi televisi di Kelurahan Banaran. Untuk menganalisis sosialisasi tersebut, peneliti menggunakan teori difusi inovasi. Jenis penelitian ini adalah penelitian kualitiatif deskriptif dengan melakukan wawancara terhadap 11 informan yang merupakan warga masyarakat Kelurahan Banaran. Dari hasil penelitian ini dapat disimpulkan bahwa sosialisasi kebijakan digitalisasi televisi yang dilakukan melalui media massa dan new media belum sepenuhnya memberikan pemahaman kepada masyarakat di Kelurahan Banaran. Isi pesan dalam sosialisasi tersebut lebih membahas keuntungan televisi digital. Masyarakat belum mengetahui maksud dan tujuan dari kebijakan digitalisasi televisi ini harus diterapkan di Indonesia. Sehingga banyak masyarakat yang tidak segera beralih ke televisi digital. Oleh karena itu diperlukan sosialisasi melalui komunikasi antarpribadi secara langsung di Kelurahan Banaran untuk memberikan edukasi terkait kebijakan digitalisasi televisi. Selain itu juga diperlukan peran tokoh masyarakat untuk ikut menyebarkan informasi agar masyarakat lebih tergerak untuk segera beralih ke televisi digital.
IL-33 and soluble ST2 in follicular fluid are associated with premature ovarian insufficiency
Authors: Tang Maoxing , Sun Xuedong , Li Ping , Deng Weifen , Zhan Xi , Sun Peng , Shi Yuhua 
Published: December 2024

BackgroundPremature ovarian insufficiency (POI) is a common reproductive disease that is associated with chronic inflammation in ovaries. Interleukin 33 (IL-33) is a pro-inflammatory IL-1 family cytokine, and functions as an alarmin reflecting inflammatory reaction. Our study aimed to investigate levels of IL-33 and its soluble receptor (sST2) in both follicular fluid (FF) and paired serum during different stages of POI, and evaluate their predictive potentials for POI. Furthermore, we attempted to determine whether IL-33 and sST2 were associated with embryo quality.MethodsA total of 148 women, including 50 patients with biochemical POI (bPOI) (10 IU/L &lt; follicle-stimulating hormone (FSH) ≤ 25 IU/L), 46 patients with POI (25 IU/L&lt;FSH ≤ 40 IU/L) and 52 age-matched control women with normal ovarian reserve were involved in this study. FF and paired serum were collected from these women. IL-33 and sST2 were measured using quantitative sandwich enzyme-linked immunosorbent assay.ResultsFF IL-33 levels were significantly increased in bPOI and POI patients compared to controls. They exhibited positive associations with FSH and luteinizing hormone (LH), whereas negative correlations with anti-Müllerian hormone (AMH), estradiol (E2), testosterone (T) and antral follicle count (AFC). Receiver operating characteristic (ROC) curve analysis showed that for POI prediction, FF IL-33 had a better predictive accuracy (AUC 0.901) with high sensitivity (82.61%) and good specificity (84.62%) than those for bPOI prediction. IL-33 levels in paired serum did not differ among three groups. Regarding sST2, its levels in FF declined with POI progression. Contrarily, they showed negative associations with FSH and LH, but positive correlations with AMH, E2, T and AFC. ROC analysis revealed that FF sST2 had comparatively weak potentials for both bPOI and POI prediction compared to those of FF IL-33. Similarly, there was no significant alteration of sST2 in paired serum among three groups. Additionally, Spearman’s correlation analysis revealed that FF IL-33 levels were negatively associated with the rates of Day-3 good-quality embryos (r=-0.206, P=0.012), whereas FF sST2 did not.ConclusionOur study revealed an increased abundance of FF IL-33, whereas an sST2 deficiency with POI development. This implies that IL-33 and sST2 levels might be associated with the development of POI.
Burden of thyroid cancer in China and worldwide from 1990 to 2021: observation, comparison, and forecast from the Global Burden of Disease Study 2021
Authors: Meng Ziang , Pan Ti , Yu Jingjing , Shi Chao , Liu Xuxu , Xue Dongbo , Wang Jing , Ma Biao 
Published: December 2024

BackgroundThyroid cancer (TC) is a prevalent malignant tumor of the endocrine system in China. Current research primarily focuses on clinical diagnosis and treatment as well as underlying mechanisms, lacking epidemiological studies on the burden of the disease in China and worldwide.MethodsThe Global Burden of Disease Study 2021 was utilized to assess the incidence, prevalence, death, and disability-adjusted life years of TC in China and worldwide from 1990 to 2021 using the Joinpoint and R software.ResultsFrom 1990 to 2021, the incidence and prevalence rates of TC in China have been consistently rising, and their growth rates are far higher than the global average. In China, TC usually occurs in patients aged 50-59, and the crude death rate generally increases with age. The burden of death among females has gradually declined, while that among males has continued to increase and surpassed females at the beginning of the 21st century. The burden of TC is heavy among middle-aged and elderly populations and the younger populations is also rapidly rising. The increased number of TC is mainly attributed to epidemiological changes, while the increase of deaths in China is primarily due to aging and population. Additionally, we predict that the age-standardized incidence rate of TC in China will continue to grow slowly over the next decade, while the age-standardized death rate will gradually decline among females and stabilize among males.ConclusionIt is imperative to avoid over-screening and over-treatments for TC. Meanwhile, we should also avoid missing aggressive types of TC that may have an impact on overall survival. Additionally, understanding the mechanisms of metastasis and improving clinical treatments should be prioritized for further investigation. TC remains a significant public health challenge in China, necessitating a careful balance of the cost-benefit ratio.
Comparing needle types and aspiration techniques in EUS-TA to optimize diagnostic efficacy and specimen quality in patients with pancreatic lesions
Authors: Shang Rumin , Han Xiangming , He Fangwei , Huang Lihua , Zeng Cui , Chen Kun , Lv Fei , Ding Xiangwu 
Published: December 2024

PurposeIn solid pancreatic lesions (SPLs), we compared the diagnostic efficacy of a 19G fine-needle aspiration (FNA) needle and a 22G ProCore fine-needle biopsy (FNB) needle, We also compared the specimen quality between the standard suction (SS) technique and heparinized wet-suction (HWS) technique.MethodsAll cases of endoscopic ultrasound-guided tissue acquisition (EUS-TA) by 19G FNA or 22G FNB for SPLs in a single-centre hospital were retrospectively reviewed. The diagnostic yield was compared between the 19G and 22G groups. Univariate and multivariate logistic regression analyses were used to identify optimal factors for a correct histological diagnosis. We also examined tissue integrity, the length of the tissue cores, and the rate of blood cell contamination between the SS and HWS groups.ResultsOne hundred seventy-one and sixty-three patients were included in the comparisons of needle types and suction techniques, respectively. The 19G group had higher histological diagnosis rates compared to the 22G group for the first pass (87.8% vs. 70.4%, p = 0.005), the second pass (82.2% vs. 65.4%, p = 0.012), the first two passes (90.0% vs. 72.8%, p = 0.004), and the final diagnosis (91.1% vs. 79%, p = 0.025). Through macroscopic on-site evaluation, a significantly higher proportion of patients in the 22G group required a third needle pass compared to the 19G group (88.9% vs. 67.8%, p = 0.002). The total procedure time was shorter in the 19G group than in the 22G group (p &lt; 0.001). The HWS group showed superiority over the SS group in terms of the total length of tissue cores (p &lt; 0.001) and the total length of white tissue cores (p = 0.005). The HWS group, compared to the SS group, can enhance the tissue integrity (p = 0.024) and reduce blood cell contamination (p = 0.040) during the first needle pass. There was no significant difference in complication rates between the needle puncture groups (p = 0.770) or the aspiration technique groups (p = 0.654).ConclusionCompared to the 22G FNB needle, endoscopists should consider using the 19G FNA needle when appropriate. Furthermore, the use of the HWS technique for the first pass is recommended to improve specimen quality.
Clinical characteristics and quality care indicators of pediatric stroke in a referral center of Colombia: eleven-year experience (pediastroke)
Authors: Valencia-Cifuentes Valeria , Llanos-Leyton Natalia , Gómez-Ayala Maria Camila , Ariza-Insignares Camila , Rivillas Julian Alejandro , Granados-Sánchez Ana María , Márquez Juan Camilo , Galvis-Blanco Laura , Cruz-Zamorano Santiago , Gómez-Castro Juan Fernando , Lasso Rubén Eduardo , Rámirez-Muñoz Luis Miguel , Castro-Varela Juan Manuel , Benavides-Llano Paula Andrea , Amaya Pablo 
Published: December 2024

ObjectiveThis study aims to describe clinical variables and quality care indicators in pediatric stroke management at a high-complexity pediatric care center in Latin America.MethodsRetrospective study of patients with stroke, aged 2–18 years from 2011 to 2021. The principal outcomes were the mRs and mortality. Differences between groups were assessed using Fisher’s exact test and the Mann–Whitney U test. We used logistic regression to explore the association between characteristics reported as relevant in literature and mortality.ResultsOne hundred thirty six patients included, with a median age of 11 years, 54% were male. 47% were hemorrhagic strokes, followed by ischemic strokes at 39%. One-third of the cases presented in hospital. 51% of the patients had no prior medical history. The most common symptoms were altered consciousness, headache, and hemiparesis. The median door-to-image time was 123 min. The most frequent etiologies in ischemic stroke were arteriopathies and cardiac pathology, while vascular malformation and coagulopathies were predominant in hemorrhagic stroke. No patient received reperfusion therapy. At discharge, 48% of patients had a favorable mRs. The mortality rate was 21%. Patients with in-hospital stroke have approximately 7.37 times the odds of dying compared to those with out-of-hospital stroke. Patients with hemorrhagic stroke have approximately 7.46 times the odds of dying compared to those with ischemic stroke.ConclusionSignificant gaps exist in the epidemiology and quality indicators of pediatric stroke care compared to adult protocols. Implementing a “Pediatric code stroke” protocol and conducting prospective studies are crucial for improving pediatric stroke care and outcomes.
Paroxysmal extreme pain disorder associated with a mutation in SCN9A gene – Case report and own experiences
Authors: Szczupak Mateusz , Wierzchowska Jolanta , Cimoszko-Zauliczna Maria , Kobak Jacek , Kosydar-Bochenek Justyna , Radys Wojciech , Szlagatys-Sidorkiewicz Agnieszka , Religa Dorota , Krupa-Nurcek Sabina 
Published: December 2024

IntroductionPain is an unpleasant sensory and emotional experience, influenced by various factors. Paroxysmal extreme pain disorder (PEPD) is a rare genetic condition characterized by sudden bouts of pain accompanied by autonomic symptoms.Material, methods and aimThis manuscript presents the case of a 9-year-old boy with paroxysmal extreme pain syndrome and provides a review of the literature. Additionally, a genealogical analysis of the boy’s family was conducted to determine the total number of affected family members. The clinical data included an analysis of genetic tests to identify the mutation confirming PEPD.Result and conclusionA mutation in the SCN9A gene causes the disease, and due to the small number of patients worldwide (around 500, according to literature reports), an effective method of preventing extreme pain attacks had not been established at the time of writing this manuscript. Based on information from scientific sources and the authors’ experiences, it can be firmly stated that various, often difficult-to-identify factors cause paroxysmal extreme pain. This syndrome necessitates further research and the exploration of effective treatment methods.