bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sabina Pasqual, comédienne-chanteuse à Madrid (1688-1727) : mère, épouse et fille de musiciens, du « duo » à la carrière soliste
Authors: Bec Caroline 
Published: June 2019

Le parcours de la comédienne-chanteuse espagnole Sabina Pasqual à Madrid, entre 1688 et 1727, inaugure la valorisation des voix féminines dans le drame lyrique espagnol, alors en plein essor, suivant l’héritage théâtral du Siècle d’Or mais aussi l’influence de l’opéra italien.Si Sabina Pasqual a bénéficié d’un savoir-faire musical familial essentiellement masculin lors de ses années de formation « en duo » avec son père, Félix Pasqual, guitariste et harpiste, puis auprès de son mari, le musicien et compositeur Ramón de Villaflor, cette artiste a été l’une des premières à connaître une carrière soliste florissante et une indépendance de plus en plus grande dans ses activités professionnelles comme dans sa vie privée.Cette chanteuse a ainsi contribué à la création du statut d’artiste lyrique féminine espagnole au XVIIIe siècle et plus largement à la redéfinition du rôle de la femme dans la société madrilène de l’époque.
Vítĕzslava Kaprálová et Bohuslav Martinů : entre émulation et complémentarité (1937-1940)
Authors: Derny Nicolas 
Published: June 2019

Fille de musiciens, Vítĕzslava Kaprálová effectue, contre l’avis paternel, un cursus complet au Conservatoire de Brno. Elle se perfectionne ensuite à Prague, auprès de Vitĕzslav Novák (composition) et de Václav Talich (direction d’orchestre). En 1937, elle rencontre Bohuslav Martinů, alors en pleins préparatifs pour la création de Juliette ou la clé des songes qui doit se tenir au Národní divadlo l’année suivante. Celui-ci s’éprend de la jeune femme, qu’il convainc de venir étudier à Paris, où il est établi depuis 1923. Rapidement, il identifie Kaprálová à l’héroïne de son opéra, avatar de l’Éternel féminin. Leur relation de maître à élève tourne à la romance dont il est possible de suivre les rebondissements dans certaines de leurs œuvres respectives. L’étude montre comment, dans ce contexte, chacun devient l’égal et la muse de l’autre, pour parvenir à former un véritable « duo ».
En solo plus souvent qu’en duo : les femmes organistes de 1790
Authors: Granger Sylvie 
Published: June 2019

L’enquête prosopographique MUSÉFREM a fait émerger un corpus de 155 femmes organistes exerçant dans les provinces à la veille de la Révolution, antérieurement plus inconnues encore que leurs collègues masculins. Derrière 70 % de celles dont on connaît les origines familiales, on entrevoit un père musicien, le plus souvent organiste lui-même, parfois une mère, qui ont eu un rôle déterminant dans l’acquisition du savoir musical. Dans l’ombre, les filles suppléent leur père malade, vieillissant ou titulaire de trop de tribunes. Mais l’orgue permet aussi une amorce de professionnalisation et près de 70 % des femmes organistes de 1790 sont célibataires. Les autres, à un âge un peu plus élevé que la moyenne, ont épousé majoritairement un musicien. Comment fonctionnaient ces couples endogames ? Quelques exemples, à Dijon, Bordeaux, Rouen ou Dreux, permettent d’approcher les réalités concrètes de leurs vies (répartition des postes, contrats, rémunérations, invisibilité féminine persistante).
Révoltes suggérées et annonce de la Révolution française : Que la fête commence de Bertrand Tavernier
Authors: Duprat Annie 
Published: June 2019

À sa sortie, le film Que la fête commence a été critiqué sur plusieurs choix du réalisateur. D’une part, la période de la Régence aurait été dépeinte de façon à la fois trop libertine et trop sombre, induisant de ce fait l’idée de la fin prochaine d’un monde vermoulu. La scène finale, qui voit des paysans brûler le carrosse a été considérée comme artificielle et fausse. Elle évoque irrésistiblement les violences de l’été 1789, la « Grande Peur » alors que le film se déroule au début des années 1720. Y aurait-il intentionnalité de Tavernier dans ce choix ?
La tomba 404 della necropoli nord-orientale di Tebe (Beozia)
Authors: Bonanno Aravantinos Margherita 
Published: June 2019

La vaste nécropole nord-est de la Thèbes antique, à environ 2 km du centre de la cité, a été explorée dans les années 1999-2001 : y ont été fouillées 843 tombes de types divers. C’est le mobilier particulièrement riche d’une tombe de jeune fille, la tombe 404 dans le secteur sud, datée du milieu du ive s. av. J.-C., qui est présenté ici. Il comporte 15 statuettes de types féminins, 3 chaussures en terre cuite, 2 cratères à figures rouges, des perles de collier en pâte de verre colorée, 5 objets coniques en terre cuite (fleurs ?). Deux statuettes féminines, l’une trônante, l’autre assise sur un klismos, ainsi que 2 représentations d’acrobates présentent un intérêt particulier.
Preoperative Warming Reduces Intraoperative Hypothermia in Total Joint Arthroplasty Patients
Authors: Kay Andrew B. , Klavas Derek M. , Hirase Takashi , Cotton Michael O. , Lambert Bradley S. , Incavo Stephen J. 
Published: June 2019

Introduction:
Perioperative hypothermia (PH) is common in patients undergoing total joint arthroplasty (TJA). A previous study at our institution identified the largest drop in core body temperature between preoperative holding and induction of anesthesia. This study evaluates the effect of preoperative warming measures on PH in TJA patients.

Methods:
A retrospective review was conducted of 672 patients undergoing TJA at our institution between April 1 and October 31, 2017. Under the new normothermia protocol, patients received warmed intravenous fluids and forced-air warming gowns in the preoperative holding area. Time and temperature data for the perioperative period were collected from the electronic health record. Chi-square and paired t-tests were used to compare between total knee arthroplasty and total hip arthroplasty patients and between new and old protocols.

Results:
In the new protocol, 173 of 672 (26%) patients were hypothermic at incision compared with 140 of 383 (37%) patients in the previous protocol (P < 0.05). The largest drop in core body temperature occurred between preoperative holding and induction of anesthesia. The duration of time from operating room entry to incision was less for normothermic than for hypothermic patients. The duration of hypothermia was similar between new and old protocols overall, but markedly fewer total hip arthroplasty patients remained hypothermic for the entire surgery under the new protocol.

Conclusion:
Adding forced-air warming preoperatively to our warming protocol reduced the rate of PH by approximately 30%. The time from entry into the operating room to the start of surgery should be minimized because patients are vulnerable to PH during this interval.
Exploração econômica do látex da hevea brasiliensis no desenvolvimento da região norte do Brasil
Authors: Brito Rui Rodrigues de , Vieira Thiago Almeida 
Published: June 2019

A humanidade vive num planeta finito, com recursos naturais também finitos, as relações da evolução da sociedade com o meio ambiente, pela agilidade e intensidade das intervenções antrópicas, caracterizam-se por um descompasso com os ciclos naturais, o desgaste e a degradação da natureza ocorrem de forma acelerada, sem que ela tenha tempo de resiliência. Este trabalho procura colaborar na tarefa de aprofundar a discussão sobre desenvolvimento regional sustentável, visando conciliar o desenvolvimento econômico da exploração do Látex com a conservação do meio ambiente, com objetivo geral de investigar a exploração econômica do látex no desenvolvimento da Região Norte do Brasil, apresentando a seringueira (Hevea brasiliensis) como instrumento de desenvolvimento sustentável, evidenciado com exploração do látex como um negócio socioambiental de longo prazo. Para realização do presente estudo foi realizado uma revisão de literatura sobre a temática com fundamento em diversos autores para tomada de decisão da pesquisa exploratória, consistindo na explicitação das teorias e conceitos que ajudaram na compreensão do objeto da pesquisa em questão. A exploração econômica proveniente da extração do látex da seringueira na Região Norte do Brasil é uma atividade tradicional, presente desde muitas décadas. E por muitos anos dominou a economia regional, o que se faz necessário em tempos atuais uma pesquisa sobre a temática do que já foi a base econômica da região. Com a realização do presente trabalho constatou-se que a exploração econômica do látex da seringueira tem se mostrado não só como um negócio lucrativo, mas também um instrumento de desenvolvimento sustentável viável para Região Norte do Brasil. Os problemas do meio ambiente são globais, mas as soluções são locais, e em tempos atuais a humanidade caminha para desenvolver técnicas de conservação e preservação do ar, da água e do solo para combater os problemas ambientais que venham a prejudicar qualquer que seja a parte integrante do meio ambiente, agregando as dimensões sociais, ecológicas, tecnológicas e econômicas ao meio ambiente.
Sequencing data discovery with MetaSeek
Authors: Hoarfrost Adrienne , Brown Nick , Brown C. Titus , Arnosti Carol 
Published: June 2019

Sequencing data resources have increased exponentially in recent years, as has interest in large-scale meta-analyses of integrated next-generation sequencing datasets. However, curation of integrated datasets that match a user’s particular research priorities is currently a time-intensive and imprecise task. MetaSeek is a sequencing data discovery tool that enables users to flexibly search and filter on any metadata field to quickly find the sequencing datasets that meet their needs. MetaSeek automatically scrapes metadata from all publicly available datasets in the Sequence Read Archive, cleans and parses messy, user-provided metadata into a structured, standard-compliant database, and predicts missing fields where possible. MetaSeek provides a web-based graphical user interface and interactive visualization dashboard, as well as a programmatic API to rapidly search, filter, visualize, save, share, and download matching sequencing metadata.
The MetaSeek online interface is available at https://www.metaseek.cloud/. The MetaSeek database can also be accessed via API to programmatically search, filter, and download all metadata. MetaSeek source code, metadata scrapers, and documents are available at https://github.com/MetaSeek-Sequencing-Data-Discovery/metaseek/.
Additional guides, tutorials, and documents are available at https://github.com/MetaSeek-Sequencing-Data-Discovery/metaseek, and on the MetaSeek website, https://www.metaseek.cloud/. MetaSeek is distributed under an MIT license.
Report of candidatus Mycoplasma haematoparvum and Mycoplasma haemocanis canine natural infections in Massambaba restinga, Brazil
Authors: Miranda Marcia Gonçalves , Alberigi Bruno , Mendes-de-Almeida Flavya , Bendas Alexandre José Rodrigues , Almosny Nadia , Paiva Jonimar Pereira , Labarthe Norma Vollmer 
Published: June 2019

Background: Tick-borne diseases are frequent in the Southeastern section of Brazil. The most prevalent canine parasites diagnosed are Ehrlichia canis, Babesia gibsoni, Babesia canis and Anaplasma platys, although Mycoplasma haemocanis and candidatus Mycoplasma haematoparvum have been registered in the country.
Methods: When two clinically healthy dogs from a suburban area of the state of Rio de Janeiro, Brazil with history of being heavily infested with ticks were examined at Idexx Reference Laboratories, California for tick panel check.
Results: One dog harbored DNA of candidatus Mycoplasma haematoparvum and the other DNA of Mycoplasma haemocanis.
Conclusions: These results suggest that monitoring for tick infestations and tick-borne parasites must be permanent in southeastern Brazil, especially due to global climate changes which may contribute to spread and increase the number of infections in the Country.
Uses for humanised mouse models in precision medicine for neurodegenerative disease
Authors: Nair Remya R. , Corrochano Silvia , Gasco Samanta , Tibbit Charlotte , Thompson David , Maduro Cheryl , Ali Zeinab , Fratta Pietro , Arozena Abraham Acevedo , Cunningham Thomas J. , Fisher Elizabeth M. C. 
Published: June 2019

AbstractNeurodegenerative disease encompasses a wide range of disorders afflicting the central and peripheral nervous systems and is a major unmet biomedical need of our time. There are very limited treatments, and no cures, for most of these diseases, including Alzheimer’s Disease, Parkinson's Disease, Huntington Disease, and Motor Neuron Diseases. Mouse and other animal models provide hope by analysing them to understand pathogenic mechanisms, to identify drug targets, and to develop gene therapies and stem cell therapies. However, despite many decades of research, virtually no new treatments have reached the clinic. Increasingly, it is apparent that human heterogeneity within clinically defined neurodegenerative disorders, and between patients with the same genetic mutations, significantly impacts disease presentation and, potentially, therapeutic efficacy. Therefore, stratifying patients according to genetics, lifestyle, disease presentation, ethnicity, and other parameters may hold the key to bringing effective therapies from the bench to the clinic. Here, we discuss genetic and cellular humanised mouse models, and how they help in defining the genetic and environmental parameters associated with neurodegenerative disease, and so help in developing effective precision medicine strategies for future healthcare.
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer
Authors: Hashiguchi Yojiro , Muro Kei , Saito Yutaka , Ito Yoshinori , Ajioka Yoichi , Hamaguchi Tetsuya , Hasegawa Kiyoshi , Hotta Kinichi , Ishida Hideyuki , Ishiguro Megumi , Ishihara Soichiro , Kanemitsu Yukihide , Kinugasa Yusuke , Murofushi Keiko , Nakajima Takako Eguchi , Oka Shiro , Tanaka Toshiaki , Taniguchi Hiroya , Tsuji Akihito , Uehara Keisuke , Ueno Hideki , Yamanaka Takeharu , Yamazaki Kentaro , Yoshida Masahiro , Yoshino Takayuki , Itabashi Michio , Sakamaki Kentaro , Sano Keiji , Shimada Yasuhiro , Tanaka Shinji , Uetake Hiroyuki , Yamaguchi Shigeki , Yamaguchi Naohiko , Kobayashi Hirotoshi , Matsuda Keiji , Kotake Kenjiro , Sugihara Kenichi ,   Japanese Society for Cancer of the Colon and Rectum
Published: June 2019

AbstractThe number of deaths from colorectal cancer in Japan continues to increase. Colorectal cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of treatments was performed, with corrections and additions made based on knowledge acquired since the 2016 version (drug therapy) and the 2014 version (other treatments). The Japanese Society for Cancer of the Colon and Rectum guidelines 2019 for the treatment of colorectal cancer (JSCCR guidelines 2019) have been prepared to show standard treatment strategies for colorectal cancer, to eliminate disparities among institutions in terms of treatment, to eliminate unnecessary treatment and insufficient treatment and to deepen mutual understanding between healthcare professionals and patients by making these guidelines available to the general public. These guidelines have been prepared by consensuses reached by the JSCCR Guideline Committee, based on a careful review of the evidence retrieved by literature searches and in view of the medical health insurance system and actual clinical practice settings in Japan. Therefore, these guidelines can be used as a tool for treating colorectal cancer in actual clinical practice settings. More specifically, they can be used as a guide to obtaining informed consent from patients and choosing the method of treatment for each patient. Controversial issues were selected as clinical questions, and recommendations were made. Each recommendation is accompanied by a classification of the evidence and a classification of recommendation categories based on the consensus reached by the Guideline Committee members. Here, we present the English version of the JSCCR guidelines 2019.
Enhancement of l-arginine production by increasing ammonium uptake in an AmtR-deficient Corynebacterium crenatum mutant
Authors: Xu Meijuan , Li Jing , Shu Qunfeng , Tang Mi , Zhang Xian , Yang Taowei , Xu Zhenghong , Rao Zhiming 
Published: June 2019

Abstract
l-Arginine is an important amino acid with extensive application in the food and pharmaceutical industries. The efficiency of nitrogen uptake and assimilation by organisms is extremely important for l-arginine production. In this study, a strain engineering strategy focusing on upregulate intracellular nitrogen metabolism in Corynebacterium crenatum for l-arginine production was conducted. Firstly, the nitrogen metabolism global transcriptional regulator AmtR was deleted, which has demonstrated the beneficial effect on l-arginine production. Subsequently, this strain was engineered by overexpressing the ammonium transporter AmtB to increase the uptake of NH4+ and l-arginine production. To overcome the drawbacks of using a plasmid to express amtB, Ptac, a strong promoter with amtB gene fragment, was integrated into the amtR region on the chromosome in the Corynebacterium crenatum/ΔamtR. The final strain results in l-arginine production at a titer of 60.9 g/L, which was 35.14% higher than that produced by C. crenatum SYPA5-5.
The Housing Cycle: What Role for Mortgage Market Development and Housing Finance?
Authors: Agnello Luca , Castro Vitor , Sousa Ricardo M. 
Published: June 2019

AbstractWe use duration analysis to assess the impact of securitization, mortgage sector liberalization and government involvement in housing finance on the length of housing booms, busts and normal times in a panel of 20 OECD countries over the period 1970Q1-2015Q4. Our results reveal that a move towards a more liberalized mortgage sector is associated with longer housing booms, while an increase in securitization is linked with shorter housing busts. They also show that the length of housing booms and busts is particularly sensitive to housing finance characteristics, but that does not seem to be the case for normal times. Additionally, government support measures do not necessarily cushion against housing busts. A careful assessment of their distributional impact, as well as their effect on the trade-off between liquidity and guarantee/loan provision, is also required to prevent (longer) housing booms. All in all, housing finance regulation may prove especially relevant to shield against the damaging effects of housing busts and the financial stability risks associated with housing booms. Monetary policy can also be an important complement to macro-prudential policies. Finally, government participation in housing finance should be designed in a way that avoids an undesirable amplification of house price fluctuations.
Privacy preserving semantic trajectory data publishing for mobile location-based services
Authors: Tan Rong , Tao Yuan , Si Wen , Zhang Yuan-Yuan 
Published: June 2019

Abstract
The development of wireless technologies and the popularity of mobile devices is responsible for generating large amounts of trajectory data for moving objects. Trajectory datasets have spatiotemporal features and are a rich information source. The mining of trajectory data can reveal interesting patterns of human activities and behaviors. However, trajectory data can also be exploited to disclose users’ privacy information, e.g., the places they live and work, which could be abused by a malicious user. Therefore, it is very important to protect the users’ privacy before publishing any trajectory data. While most previous research on this subject has only considered the privacy protection of stay points, this paper distinguishes itself by modeling and processing semantic trajectories, which not only contain spatiotemporal data but also involve POI information and the users’ motion modes such as walking, running, driving, etc. Accordingly, in this research, semantic trajectory anonymizing based on the k-anonymity model is proposed that can form sensitive areas that contain k − 1 POI points that are similar to the sensitive points. Then, trajectory ambiguity is executed based on the motion modes, road network topologies and road weights in the sensitive area. Finally, a similarity comparison is performed to obtain the recordable and releasable anonymity trajectory sets. Experimental results show that this method performs efficiently and provides high privacy levels.
Is Post-discharge Rehabilitation Timing Associated with 90-Day Readmission in Primary Total Joint Arthroplasty?
Authors: Pathak Shweta , Ganduglia Cecilia M. , Awad Samir S. , Chan Wenyaw , Swint John M. , Morgan Robert O. 
Published: June 2019

Background Physical therapy (PT) is an accepted standard of care after total joint arthroplasty (TJA) and essential to maximizing joint functionality and minimizing complications that lead to readmission. However, evidence-based guidelines about appropriate post-discharge rehabilitative care are not well-defined in the orthopedic literature. Purposes We sought to determine the average timing for receiving PT rehabilitation and to evaluate the association between PT rehabilitation timing and unplanned readmission within 90 days of a TJA patient being discharged home from acute care. Methods This retrospective study examined 11, 545 joint procedures using claims data for the years 2008 to 2013. Outcomes were assessed using a population-averaged approach to regression models. Results The average time for initiating PT was 4 days for knee arthroplasty and 6 days for hip arthroplasty in patients discharged home from acute care. Most patients (89%) began PT consultation or supervised exercises during the first week after discharge. The type of joint surgery considerably modified the effect of rehabilitation timing on the likelihood of readmission. Later initiation of rehabilitation was associated with a higher probability of 90-day readmission in both knee and hip arthroplasty, with the effect of rehabilitation timing being more pronounced in hip rather than knee arthroplasty 2 weeks post-discharge from acute care. Conclusions Timing for initiating PT may be an important modifiable factor that can affect readmission in patients discharged home from acute care after TJA. Further exploration of the role of PT timing along with other factors such as dosage and frequency among such patients is needed.
The influence of the physical context and knowledge of artworks on the aesthetic experience of interactive installations
Authors: Szubielska Magdalena , Imbir Kamil , Szymańska Anna 
Published: June 2019

AbstractIn the current study, the influence of the physical context and the knowledge of artworks on the aesthetic experience of installation art is tested for the first time. We assessed non-experts in the field of art (N = 158) who viewed interactive installations in either the art gallery context or the classroom. Some participants knew both the artworks’ titles and the curator descriptions, some knew only the titles, and some had no contextual information. We tested both the aesthetic emotions and the aesthetic judgments. For the measurement of aesthetic emotions, we used the Self-Assessment Manikin approach including the traditional dimensions of affect and the measurement of recently-proposed dimensions such as origin or subjective significance. The study replicated previous findings that the gallery context enhances the aesthetic experience – both of art appreciation and aesthetic emotions. Moreover, our results showed that the emotions caused by viewing the installation in the gallery had more of an automatic source (metaphorically coming “from the heart”) and were more subjectively significant than aesthetic emotions experienced in the classroom context. Curatorial information increased the understanding and appreciation of the works of installation art, and also caused the aesthetic emotion to be more positive and more intensive; while having knowledge about the titles did not influence the aesthetic experience.