bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving Abdominal Plastic Scars with a Dietary Supplement—A Comparative Study
Authors: Haiun Mathieu , Barbara Hersant , Durazzo Adrien , Sid-Ahmed-Mezi Mounia , Meningaud Jean-Paul 
Published: October 2018

Introduction:
Massive weight loss following bariatric surgery has a major functional and aesthetic impact on patients. Many patients are nonetheless reluctant to undergo plastic surgery in connection with their former obesity because they fear potentially large scars, even though such scars are not visible (ie, they are covered by undergarments).

Purpose:
The aim of this study was to evaluate the quality of wound healing in patients receiving Celergen supplementation following abdominoplasty, compared with a control group. The hypothesis was that supplementation would speed up wound healing and improve scar quality.

Materials and Methods:
We conducted a prospective, monocentric, controlled study of patients undergoing abdominoplasty. A group of patients received Celergen, a food supplement, for 3 months and were monitored for 1 year after their surgery.

Results:
Of 33 patients who underwent abdominoplasty, 25 received Celergen supplements. There was no significant difference between the 2 groups. The mean time to wound healing was significantly better in the group receiving supplementation compared with the control group [respectively, 24.6 ± 9.31 days and 34 ± 13.48 days (P = 0.03)]. The Patient and Observer Scar Assessment Scale (POSAS) observer score was significantly better at 1 year in the group receiving supplementation compared with the control group [12.68 ± 6.6 and 17.38 ± 5.24 (P = 0.01), respectively]. There was no significant difference in the total POSAS score at 1 year (P = 0.166).

Conclusion:
Celergen supplementation significantly improved the time to healing and the POSAS observer score at 1 year for patients undergoing abdominoplasty.
Function Preservation of the Upper Lip after Tumor Resection Using Residual Orbicularis Oris Muscle and Attached Levator Labii Superioris Alaeque Nasi
Authors: Kuwahara Masamitsu , Yurugi Satoshi , Sasaki Chikako , Nakanishi Takashi , Takeuchi Mika , Miyata Riyo , Harada Masayuki , Masuda Yasumitsu 
Published: October 2018

Summary:
We report a case, function preservation of the upper lip after tumor resection was possible using residual orbicularis oris muscle and attached levator labii superioris alaeque nasi. Patient was 67-year-old male with squamous cell carcinoma at the vermilion border. The tumor was resected with an 8-mm margin, leaving the oral mucosa as intact as possible. To reconstruct the red lip, we used the oral mucosa as a rotational transposition flap. The white lip was reconstructed with a cheek rotation flap. A levator labii superioris alaque nasi muscle flap, which was attached to the remaining orbicularis oris muscle, was used to increase marginal lip volume. The movement of the reconstructed lip was good. At 9 postoperative months, induration of the red lip was palpable, and we suspected that the blood supply to the levator labii superioris alaque nasi was borderline insufficient. Slight drooping of the reconstructed lip occurred. We dissected this was caused by dissection of mid facial muscles from orbicularis oris muscle to ease downward rotation of the cheek flap and obscure the original nasolabial fold. Although some drooping and induration of the lip occurred, the white and red lip were reconstructed in a single-stage procedure, which resulted in good movement and preserved the function of the orbicularis oris muscle.
Evaluation of Pancreatic Fibrosis With Acoustic Radiation Force Impulse Imaging and Automated Quantification of Pancreatic Tissue Components
Authors: Fujita Yusuke , Kitago Minoru , Abe Tokiya , Itano Osamu , Shinoda Masahiro , Abe Yuta , Yagi Hiroshi , Hibi Taizo , Ishii Masatsugu , Nakano Yutaka , Okuma Kiyoshi , Hashimoto Masahiro , Takeuchi Ayano , Masugi Yohei , Jinzaki Masahiro , Sakamoto Michiie , Kitagawa Yuko 
Published: October 2018

Objectives
The aim of this study was to determine whether computer-assisted digital analysis and acoustic radiation force impulse (ARFI) imaging were useful for assessing pancreatic fibrosis, and if ARFI imaging predicted postoperative pancreatic fistula (POPF).

Methods
Seventy-eight patients scheduled to undergo pancreatic resection were enrolled. Shear wave velocity (SWV) at the pancreatic neck was measured preoperatively using ARFI imaging. Pancreatic tissue components on a whole slide image were quantified using an automatic image processing software. The relationship between SWV, fibrotic tissue content, and POPF incidence and clinical severity was analyzed.

Results
The median collagen fiber, fatty tissue, and acinar cell contents were 11.6%, 8.5%, and 61.3%, respectively. Unlike fatty tissue, collagen fiber content and acinar cells were correlated with SWV (ρ = 0.440, P < 0.001 and ρ = −0.428, P < 0.001, respectively). Although collagen fiber content and SWV were associated with the overall incidence of POPF (P = 0.004 and 0.001, respectively), collagen fiber content and SWV had no statistical correlation with clinically relevant POPF (P = 0.268 and 0.052, respectively).

Conclusions
We objectively quantified the pancreatic tissue components using an automatic image processing software. Shear wave velocity was significantly related to collagen fiber content and suggests that ARFI imaging can be useful for evaluating pancreatic fibrosis.
The Best Practice for Increasing Telephone Outreach
Authors: Vergara Franz H. , Sullivan Nancy J. , Sheridan Daniel J. , Davis Jean E. 
Published: October 2018

Purpose of Study:
Many hospitals established telephone follow-up (TFU) programs to improve care transitions and reduce hospital readmissions. However, there is a lack of knowledge on how to increase the outreach of TFU programs. This integrative review aims to answer the clinical practice question, “What is the best practice for increasing telephone follow-up reach rates post-hospital discharge?”

Primary Practice Setting:
The primary setting evaluated in this review was hospital-based phone call programs that are conducting post-hospital discharge TFU.

Methodology:
In this integrative review, we searched studies published between January 2003 and November 2017. We searched 5 electronic databases including PubMed, EMBASE, CINAHL, Web of Science, and Cochrane. The Johns Hopkins Nursing Evidence-Based Practice model was used to critically analyze and synthesize the selected articles.

Results:
Nine articles were reviewed, and this study uncovered that pre-hospital face-to-face meeting might increase TFU reach rates. However, most studies calculated reach rates using only frequencies/percentages. This contributed to our low-quality rating on most of the reviewed studies.

Implications for Case Management Practice:
This review identified that TFU, as a component of a care coordination program, may reduce hospital readmissions and control health care utilization. However, few studies (n = 2) used TFU reach rates as a major study outcome to determine the impact of face-to-face meetings on phone outreach. Therefore, the evidence is limited to inform case management practice to increase phone outreach post-hospital discharge. It is recommended to conduct further research and test different methods that may increase phone outreach.
The New Age of Bullying and Violence in Health Care: Part 4
Authors: Fink-Samnick Ellen 
Published: October 2018

Disrespect among the health and behavioral health workforce may have reached the point of no return. The industry is on heightened alert, as the disruptive behaviors of bullying and lateral violence, plus escalating incidents of workforce harassment and workplace violence incidents, impact every practice setting. These behaviors contribute to concerns around client and professional safety, quality-of-care processes, as well as workforce retention and mental health.

Purpose/Objectives:
This article:

Defines a hostile workplace;Identifies types of toxic employees;Discusses types of workplace harassment;Reviews the impact of organizational culture on these disrupters; andExplores strategies and legislation to manage workplace violence across practice domains.

Primary Practice Setting(s):
Applicable to all health and behavioral health settings where case management is practiced.

Findings/Conclusions:
Despite glaring improvements in how care is rendered and an enhanced focus on quality delivery of care, organizations must address cultures that support as opposed to negate disruptive workplace behaviors. The emerging regulatory and organizational initiatives to reframe the delivery of care will become meaningless without consistent attention to enforcement of regulatory, policy, and prevention actions.

Implications for Case Management Practice:
Professionals who hesitate to confront and address incidents of disruptive and oppressive behavior in the health care workplace potentially practice unethically. Bullying has fostered a dangerous culture of silence in the industry, one which impacts client safety, quality care delivery, plus has longer term behavioral health implications for the professionals striving to render care. Add the escalating numbers specific to workplace violence and the trends speak to an atmosphere of safety and quality in the health care workplace that puts clients and professionals at risk.
Angiopoietin Level Trajectories in Toddlers With Severe Sepsis and Septic Shock and Their Effect on Capillary Endothelium
Authors: Pierce Richard W. , Shabanova Veronika , Canarie Michael , Pinto Mathew , da Silva Yong Sing , Bhandari Vineet , Giuliano John S. 
Published: October 2018

ABSTRACT

Objective:
Angiopoietins are postulated diagnostic biomarkers in children and adults with severe sepsis and septic shock. The diagnostic value of angiopoietins in children less than 5 years old has not been established, nor has their effect on permeability in the capillary microvasculature. We aim to determine if levels of angiopoietin-1 or -2 (angpt-1, -2) are diagnostic for severe sepsis/shock in young children and whether they affect the permeability of cultured human dermal microvascular endothelial cells (HDMEC).

Design:
Prospective observational study of children < 5 years old. Patients were classified as non-systemic inflammatory response syndrome (SIRS), SIRS/sepsis and severe sepsis/septic shock.

Setting:
Tertiary care pediatric hospitals.

Patients:
Critically ill children.

Interventions:
None.

Measurements:
Plasma angpt-1 and -2 levels were measured with enzyme-linked immunoassays. Expression of angpt-2 in endothelial cells was assessed with quantitative polymerase chain reaction. Permeability changes in cultured HDMECs were assessed with transendothelial electrical resistance measurements.

Results:
Angpt-1 levels were significantly higher in younger children compared with levels found in previous study of older children across disease severity (all P < 0.001). Angpt-2 was significantly higher in this cohort with severe sepsis/septic shock compared with children without SIRS and SIRS/sepsis (all P < 0.003). Angpt-2/1 ratio was also elevated in children with severe sepsis/septic shock but an order of magnitude less than older children (P < 0.02, P = 0.002). Angpt-1 and -2 did not affect basal HDMEC permeability or modulate leak in isolation or in the presence of tumor necrosis factor (TNF).

Conclusions:
Angpt-2 levels and the angpt-2/1 ratio are appropriate diagnostic biomarkers of severe sepsis/septic shock in children less than 5 years old. Neither angpt-1 nor -2 affects basal HDMEC permeability alone or modulates TNF induced capillary leak.
Managing anaemia in bone marrow failure syndromes
Authors: Narayanan Srinivasan 
Published: October 2018

Purpose of review
Anaemia is a common haematological presentation in patients with bone marrow failure, yet a challenging condition to treat. As anaemia has a direct impact on the patient's symptoms, managing anaemia in the common bone marrow failure conditions, such as myelodysplastic syndrome will help to improve the quality of life. This review discusses the available treatment options and the benefit of improving the haemoglobin level.

Recent findings
Managing anaemia effectively has shown to improve the patient outcome, yet treatment option remain limited. Recently, activin inhibitors such as Luspatercept have shown to be effective in patients’ refractory to ESAs and further clinical trials are ongoing to explore this further.

Summary
Transfusion still remains the mainstay of treatment in patients not suitable, lost response or refractory to erythropoiesis-stimulating agents (ESAs). Majority of these patients are not suitable for definite treatment options such as bone marrow transplantation. The aim of treatment remains improving the quality of life and newer therapeutic options may offer better and more sustained response.
Increased Health Care Utilization in Dementia Subtypes Before Diagnosis
Authors: Albrecht Jennifer S. , Hanna Maya , Kim Dure , Perfetto Eleanor M. 
Published: October 2018

Introduction:
Prior studies have reported higher health care utilization (HCU) leading up to diagnosis of the Alzheimer disease and related dementia (ADRD), but none have assessed variation in HCU by ADRD subtype or examined disease-specific HCU. The objectives of this study were to identify ADRD subtypes and: (1) characterize all-cause and (2) disease-specific HCU during the 3 years preceding diagnosis, and (3) determine if HCU varied by ADRD subtype.

Methods:
We used data from the OptumLabs Data Warehouse 2008 to 2014 to identify ADRD subtypes (total N=36,838) using an algorithm based on temporal sequencing of diagnoses and provider type. Annual counts of all-cause and disease-specific HCU in each of the 3 years preceding ADRD diagnosis were regressed on ADRD subtypes with mild cognitive impairment (MCI) as the reference group, year, and other variables.

Results:
HCU increased over time, was highest in the outpatient setting, and varied by ADRD subtype. Compared with MCI, highest HCU was observed in vascular and nonspecific dementia. Compared with MCI, most subtypes had elevated disease-specific HCU.

Discussion:
Variation in HCU by ADRD subtype points to different pathways to diagnosis and patterns of use.
Recurrent Superior Oblique Myokymia Treated by Distal Tendon Extirpation
Authors: Law Megan X. , Hoyt Creig S. , Horton Jonathan C. 
Published: October 2018

Background:
We describe successful surgical treatment of superior oblique myokymia, which had recurred after superior oblique tenectomy.

Methods:
Single case report.

Results:
The distal stump of the superior oblique tendon was extirpated by stripping it from the globe. The ipsilateral superior rectus muscle also was recessed, to correct a hypertropia that had resulted from the original superior oblique tenectomy.

Conclusions:
Complete removal of the distal superior oblique muscle tendon provided definitive relief of superior oblique myokymia. Superior rectus muscle recession, combined with previous inferior oblique myectomy, compensated effectively for loss of superior oblique function.
Malaria control dynamics may explain inconsistent outcomes from bednet trials: a modeling study
Authors: Orsborne James , Walker Thomas , Yakob Laith 
Published: October 2018

AbstractBACKGROUNDLong-lasting insecticidal bednets have unparalleled efficacy in reducing malaria burden. However, insecticidal resistance and bednet avoidance behaviors among the mosquito vectors are now widespread.METHODSReviewing the relevant field and semi-field studies highlights the ubiquity of zoophagic and spatiotemporal (biting outdoors or at different times of day) plasticity among vectors in response to bednet deployment. Transmission models coupled with the population genetics of vectors are developed to assess the impact on malaria control caused by insecticide resistance and the avoidance behaviors of mosquitoes.RESULTSInteractions between physiological resistance and behavioral resilience among mosquito vectors can significantly impact malaria control efforts both in the short- and long-term. The possibility of misleading observations from injudiciously timed assessments of malaria control programs is demonstrated through simulation.CONCLUSIONSCurrently, there are no guidelines to inform when during a bednet trial its effectiveness should be measured. The importance of this oversight is described in the context of recent randomized controlled bednet trials.
Motion and force control method of 7-DOF cable-driven rehabilitation exoskeleton robot
Authors: Ni Wencheng , Li Hui , Jiang Zhihong , Zhang Bainan , Huang Qiang 
Published: October 2018

Purpose
The purpose of this paper is to design an exoskeleton robot and present a corresponding rehabilitation training method for patients in different rehabilitation stages.

Design/methodology/approach
This paper presents a lightweight seven-degrees-of-freedom (DOF) cable-driven exoskeleton robot that is wearable and adjustable. After decoupling joint movement caused by a cable-driven mechanism, active rehabilitation training mode and passive rehabilitation training mode are proposed to improve the effect of rehabilitation training.

Findings
Simulations and experiments have been carried out, and the results validated the feasibility of the proposed mechanism and methods by a fine rehabilitative effect with different persons.

Originality/value
This paper designed a 7-DOF cable-driven exoskeleton robot that is suitable for patients of different body measurements and proposed the active rehabilitation training mode and passive rehabilitation training mode based on the cable-driven exoskeleton robot.
Comprehensive identification of aircraft coordination feature based on complete importance modeling and its engineering application
Authors: Guo Feiyan , Zou Fang , Liu Jian Hua , Zhao Bo , Wang Zhongqi 
Published: October 2018

Purpose
Coordination feature (CF) is the information carrier in dimension and shape transfer process in aircraft manufacturing. The change of its geometric size, shape, position or other attributes would affect the consistency of accumulated errors between two or more assemblies. To identify these “key characteristics” that have a close relationship with the assembly precision, a comprehensive method was developed under digital manufacturing environment, which was based on importance calculation. The multi-hierarchy and multi-station assembly process of aircraft products were also taken into consideration.

Design/methodology/approach
First, the interaction and evaluation relationship between components at different manufacturing stages was decomposed with a hierarchical net. Second, to meet coordination accuracy requirements, with the integrated application of Taguchi quality loss function, accuracy principal and error correction coefficient H, the quality loss between target features and candidate features at adjacent assembly hierarchies were calculated, which was based on their precision variation. Third, the influence degree and affected degree of the features were calculated with DEMATEL (decision-making trial and evaluation laboratory) method, and the concepts of centrality degree index and cause degree index were proposed for calculating the complete importance degree to eventually identify the CFs.

Findings
Based on the proposed methodology, CFs, affecting the skin profile and the flush coordination accuracy, were successfully identified at different assembly hierarchies to a certain type of wing flap component.

Originality/value
Benefit results for the engineering application showed that the deviation of skin profile was more accurate than before, and the tolerance was also closer to the centerline of required assembly precision range. Moreover, the stability in the assembly process was increased by 26.9 per cent, which could bring a higher assembly quality and an enhancement on aircraft’s flight performance.
A hybrid artificial fish swam algorithm for disassembly sequence planning considering setup time
Authors: Guo Jun , Zhong Jingcheng , Li Yibing , Du Baigang , Guo Shunsheng 
Published: October 2018

Purpose
To improve the efficiency of end-of-life product’s disassembly process, this paper aims to propose a disassembly sequence planning (DSP) method to reduce additional efforts of removing parts when considering the changes of disassembly directions and tools.

Design/methodology/approach
The methodology has three parts. First, a disassembly hybrid graph model (DHGM) was adopted to represent disassembly operations and their precedence relations. After representing the problem as DHGM, a new integer programming model was suggested for the objective of minimizing the total disassembly time. The objective takes into account several criteria such as disassembly tools change and the change of disassembly directions. Finally, a novel hybrid approach with a chaotic mapping-based hybrid algorithm of artificial fish swarm algorithm (AFSA) and genetic algorithm (GA) was developed to find an optimal or near-optimal disassembly sequence.

Findings
Numerical experiment with case study on end-of-life product disassembly planning has been carried out to demonstrate the effectiveness of the designed criteria and the results exhibited that the developed algorithm performs better than other relevant algorithms.

Research limitations/implications
More complex case studies for DSP problems will be introduced. The performance of the CAAFG algorithm can be enhanced by improving the design of AFSA and GA by combining them with other search techniques.

Practical implications
DSP of an internal gear hydraulic pump is analyzed to investigate the accuracy and efficiency of the proposed method.

Originality/value
This paper proposes a novel CAAFG algorithm for solving DSP problems. The implemented tool generates a feasible optimal solution and the considered criteria can help the planer obtain satisfactory results.
Design of the tip state estimator for hybrid-structured flexible manipulator based on SDFT and FLAKF
Authors: Long Teng , Li En , Fan Junfeng , Yang Lei , Liang Zize 
Published: October 2018

Purpose
This paper aims to design a tip state estimation method for a hybrid-structured flexible manipulator (HSFM) with one rotating joint and one telescopic joint in the vertical plane.

Design/methodology/approach
The HSFM model is decomposed into a static deflection model and a vibration model. The sliding discrete Fourier transform (SDFT) is used to filter the high frequency noise and obtain main vibration components to represent the vibration model. Then, a novel fuzzy logic adaptive Kalman filter (FLAKF) is designed to estimate the state of a vibrational equilibrium position. The complete tip state of the HSFM is obtained by superimposing the FLAKF filter results with the SDFT vibration analysis results.

Findings
Both the simulation results and physical experimental results verify the effectiveness of the proposed tip state estimation method. The vibration analysis based on SDFT is used to represent the vibration model and reduce the computational complexity in the process of solving differential equation. The proposed FLAKF can effectively increase the stability and robustness of the estimator.

Originality/value
In this paper, the tip state estimation problem of the HSFM in vertical plane is first proposed. The effect of gravity on the HSFM is considered by the static deflection model. A precise tip state estimator is designed by a closed loop SDFT and a novel FLAKF, which can provide an accurate feedback for the vibration control controller and make an accurate evaluation of the control effect.