bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of the Transgender Adolescent Stress Survey–Minority Stress (TASS-MS)
Authors: Goldbach Jeremy T. , Schrager Sheree M. , Wood Jules K. , O’Brien Rory P. , Dunlap Shannon L. , Rhoades Harmony 
Published: December 2024

ObjectiveThis study aimed to create and validate a novel measure of gender-related minority stress in transgender and non-binary adolescents (TNBA). TNBA face higher risks of varied behavioral health concerns compared to their cisgender peers, a disparity often attributed to the presence of minority stress due to discrimination. To date, no comprehensive measures of gender-related minority stress exist for use with TNBA.MethodThe present study recruited a U.S. national sample (N = 444, aged 12–17; 65.5% White, 9.5% Black, 9.5% Latine, 15.5% other ethnicity; 34.7% transmasculine, 17.3% transfeminine, 38.3% non-binary, 9.5% agender) of TNBA. An initial item pool was developed from life history calendars, a modified Delphi process, and cognitive interviews with TNBA. Analytic methods including principal components analysis, item response theory, measurement invariance testing, and reliability analyses were conducted to establish the final scale. Concurrent validity was established across behavioral outcomes (mental health, suicidal thoughts and behavior, substance use), and convergent and divergent validity compared the Transgender Adolescent Stress Survey–Minority Stress (TASS-MS) to existing measures of gender-related minority stress.ResultsThe TASS-MS and its subscales (disaffirmation, visibility and internalized transnegativity, family) were significantly associated with anxiety and depressive symptoms, PTSD symptoms, suicidal behaviors, non-suicidal self-injury, marijuana, and prescription drug use. The TASS-MS was moderately and weakly correlated with convergent and divergent measures, respectively, indicating specificity to minority stress.ConclusionThe TASS-MS is a reliable and valid measure for future research with TNBA. It is inclusive and usable by all gender minority adolescents, uses a standard simple scoring system, and assesses adolescent-specific stressors.
Mental health variables affecting Quality of Life (QOL) among healthcare workers during the COVID-19 pandemic in Jazan City, Saudi Arabia
Authors: Alfaifi Amal Jaber , Abdaly Ahmed Yahia , Alallah Sultan Musa , Zaino Mohammad , El-Setouhy Maged 
Published: December 2024

BackgroundHealth workers directly involved in the diagnosis, treatment, and care of patients with COVID-19 are at risk of developing mental health symptoms.ObjectiveThe study aimed to assess the quality of life (QoL) of healthcare workers at Prince Mohammed bin Nasser Tertiary Hospital in Jazan during the COVID-19 pandemic, with a focus on the relationship between QoL and stress, anxiety, and depression. Pandemic.MethodsThis was a cross-sectional study conducted among healthcare workers at Prince Mohammed bin Nasser Hospital in the Jazan. The study included a sample of 352 healthcare workers. Data was collected through a self-administered questionnaire pertaining to sociodemographic characteristics and the 21-item Depression Anxiety Stress Scale questionnaire, SF-36, for QoL. Descriptive statistics, frequencies, and percentages were used. A chi-squared test was performed to compare categorical data. A one-way ANOVA was performed to compare the effect of disorder variables on QoL. Multiple linear regression analyses were carried out to discern the differences between the different groups of participants in QoL measures.ResultsOur results showed a poor QoL among those with a chronic disease (p = 0.002), who worked in the COVID-19 department (p = 0.030) and those who experienced the death of relatives or friends due to COVID-19 (p = 0.003).ConclusionHealthcare workers, particularly those with chronic diseases or who had lost relatives to COVID-19, exhibited significantly lower QoL levels, especially those working directly in COVID-19 departments.
Greater neural pattern similarity to the native language is associated with better novel word learning
Authors: Feng Yuan , Li Aqian , Qu Jing , Li Huiling , Liu Xiaoyu , Zhang Jingxian , Yang Jiayi , Mei Leilei 
Published: December 2024

IntroductionPrevious neuroimaging studies on bilingualism revealed that individuals tend to apply their native-language (L1) neural strategies to second language (L2) learning and processing. Nevertheless, it is still unclear how the utilization of the L1 neural strategies affects visual word learning in a new language.MethodsTo address this question, the present study scanned native Chinese speakers while performing implicit reading tasks before 9-day form-meaning learning in Experiment 1 and before 12-day comprehensive word learning in Experiment 2. To quantify the application of the L1 neural strategies in novel word learning, representational similarity analysis (RSA) was used to compute the neural pattern similarity (PS) between the L1 and artificial language (i.e., cross-language PS) before training.ResultsUnivariate analysis revealed that reading both Chinese words (CWs) and artificial language words (ALWs) elicited activations in a typical reading network. More importantly, RSA revealed that greater pre-training cross-language PS in the left fusiform gyrus was associated with higher learning rate.DiscussionThese findings directly reveal the facilitating role of the L1 neural strategies in novel word learning and further extend the assimilation hypothesis from the utilization of the L1 neural network in L2 learning to its learning outcomes.
Comparative analysis of cognitive behavioral therapy and dialectical behavior therapy in enhancing psychological capital among medical students: a randomized controlled trial
Authors: Dong Cexin , Zhao Jinfa , Wei Yating , Wu Deyuan , Cai Zhu 
Published: December 2024

BackgroundMedical students are confronted with a complex stress environment, encompassing academic challenges, residency training, and future workplace pressures. Therefore, the exploration of effective psychological capital intervention strategies is crucial for enhancing their mental health and promoting career development.ObjectiveThe aim of this study was to evaluate the efficacy of group cognitive-behavioral therapy (GCBT) and dialectical behavior therapy (DBT) in boosting the psychological capital of medical students and to compare the advantages and disadvantages of these two therapies.MethodA randomized controlled trial was conducted, recruiting 56 second-year medical students, who were randomly assigned into three groups: GCBT intervention group, DBT intervention group, and control group. The intervention period lasted for 6 weeks, during which the GCBT and DBT groups received respective interventions, while the control group did not receive any intervention.ResultsRegardless of whether GCBT or DBT was used as an intervention, the psychological capital levels of the intervention group students showed significant improvement (mean ± SD, p &lt; 0.05), with effect sizes ranging from 0.324 to 0.667. Further follow-up studies revealed that this improvement remained stable within 1 month post-intervention (mean ± SD, p &lt; 0.05).ConclusionBoth group cognitive-behavioral therapy (GCBT) and dialectical behavior therapy (DBT) have been proven to be effective psychological intervention methods, capable of significantly enhancing the psychological capital of medical students. However, there are certain differences in their effects, providing diverse intervention options to cater to the varied psychological needs of medical students.
Non-communicable diseases related multimorbidity, catastrophic health expenditure, and associated factors in Ernakulam district
Authors: Joy Sarah , Sreedevi Aswathy , Bhaskaran Renjitha 
Published: December 2024

BackgroundMultimorbidity, the coexistence of two or more chronic conditions in an individual, has emerged as a significant public health challenge with profound economic implications, exerting substantial strain on healthcare systems and economies worldwide. This study aimed to estimate the prevalence of non-communicable diseases (NCD) related multimorbidity, catastrophic health expenditure (CHE), and associated factors among adults aged ≥40 years in Ernakulam district.MethodsA community-based cross-sectional study was conducted among 420 individuals aged ≥40 years using population probability sampling. The tools used were the Multimorbidity Assessment Questionnaire for Primary Care (MAQ-PC), the WHO STEPS Questionnaire, and the Patient Health Questionnaire-9 (PHQ-9), which assessed non-communicable diseases, diet, physical activity, smoking, alcohol consumption, and depression. A pretested semi-structured questionnaire collected data on health and household expenditures. Multimorbidity was defined as having two or more self-reported NCDs, and CHE was identified when health costs exceeded 10% of a household’s expenditure in the past month. Multivariable logistic regression was performed to find independent predictors of multimorbidity and CHE.ResultsThe mean age of participants was 60.02 ± 10 years. The prevalence of NCD multimorbidity was 42.6% (95% CI: 37.9–47.3%). The most common dyad was diabetes and hypertension (24.5, 95% CI: 20.4–28.6%). Higher odds of multimorbidity were observed in those aged ≥60 years (aOR = 3.03, 95% CI: 1.95–4.73), unmarried/widowed/divorced (aOR = 2.15, 95% CI: 1.28–3.63), unemployed (aOR = 1.81, 95% CI: 1.14–2.87), and tobacco users (aOR = 3.72, 95% CI: 1.85–7.48). Approximately 32.4% (95% CI: 25.5–39.3%) of households incurred catastrophic health expenditure (CHE) by treating adults with multimorbidity. Age ≥ 60 (aOR = 2.39, 95% CI: 1.99–5.77) and use of outpatient services (aOR = 4.09, 95% CI: 2.01–8.32) were independently associated with higher odds of CHE. IP services and each additional morbidity add ₹22,082.37 (β = 0.557, p &lt; 0.001, 95% CI: ₹17,139.88– ₹27,024.86) and ₹1,278.75 (β = 0.128, p = 0.044, 95%CI: ₹35.58–₹2,521.92) to healthcare costs, respectively.ConclusionThe high prevalence of multimorbidity and associated CHE among individuals over 60 years highlights the urgent need for the National Programme for the Prevention and Control of Non-Communicable Diseases to prioritise multimorbidity and its management, especially above 60 years within this age group.
Evaluation of large language models under different training background in Chinese medical examination: a comparative study
Authors: Zhang Siwen , Chu Qi , Li Yujun , Liu Jialu , Wang Jiayi , Yan Chi , Liu Wenxi , Wang Yizhen , Zhao Chengcheng , Zhang Xinyue , Chen Yuwen 
Published: December 2024

BackgroundRecently, Large Language Models have shown impressive potential in medical services. However, the aforementioned research primarily discusses the performance of LLMs developed in English within English-speaking medical contexts, ignoring the LLMs developed under different linguistic environments with respect to their performance in the Chinese clinical medicine field.ObjectiveThrough a comparative analysis of three LLMs developed under different training background, we firstly evaluate their potential as medical service tools in a Chinese language environment. Furthermore, we also point out the limitations in the application of Chinese medical practice.MethodUtilizing the APIs provided by three LLMs, we conducted an automated assessment of their performance in the 2023 CMLE. We not only examined the accuracy of three LLMs across various question, but also categorized the reasons for their errors. Furthermore, we performed repetitive experiments on selected questions to evaluate the stability of the outputs generated by the LLMs.ResultThe accuracy of GPT-4, ERNIE Bot, and DISC-MedLLM in CMLE are 65.2, 61.7, and 25.3%. In error types, the knowledge errors of GPT-4 and ERNIE Bot account for 52.2 and 51.7%, while hallucinatory errors account for 36.4 and 52.6%. In the Chinese text generation experiment, the general LLMs demonstrated high natural language understanding ability and was able to generate clear and standardized Chinese texts. In repetitive experiments, the LLMs showed a certain output stability of 70%, but there were still cases of inconsistent output results.ConclusionGeneral LLMs, represented by GPT-4 and ERNIE Bot, demonstrate the capability to meet the standards of the CMLE. Despite being developed and trained in different linguistic contexts, they exhibit excellence in understanding Chinese natural language and Chinese clinical knowledge, highlighting their broad potential application in Chinese medical practice. However, these models still show deficiencies in mastering specialized knowledge, addressing ethical issues, and maintaining the outputs stability. Additionally, there is a tendency to avoid risk when providing medical advice.
Gamified experience design: a case study on China's immersive tourist blocks in historic cities
Authors: Zheng Yuqi , Zhang Jiayi , Li Jinsha 
Published: December 2024

IntroductionIn the context of the internet economy era, historic cities face increasing pressure to attract tourists through effective urban design strategies. Immersive districts, particularly in historic Chinese cities, have emerged as an innovative approach to enhance tourism experiences, achieving notable success. This paper explores the use of immersive design strategies in the Guitanglou (簋唐楼) district in Xi'an, China, with a focus on gamification theory.MethodsThe study employs in-depth interviews and content analysis to examine the design strategies employed in the Guitanglou immersive district. Through these methods, the research investigates how immersive experiences can be used to enhance tourist engagement in historic sites.ResultsThe research introduces a “4S” design model, consisting of Scene, Socialization, Story, and Stimulus. The model suggests that by innovating design within these four key areas, tourists can engage more deeply with the immersive district, resulting in stronger cultural resonance and emotional connections.DiscussionThis study offers new insights into tourism and urban design, highlighting how immersive districts can serve as effective platforms for disseminating historical and cultural values. The findings suggest that leveraging communication strategies familiar to digital natives can create a balance between cultural preservation and economic growth, offering a fresh perspective on urban design in historic settings.
Graying arts access: crafting creative online programming to promote older adults' artistic engagement in and beyond pandemic time
Authors: McFarland Jami , Rice Carla , Changfoot Nadine , La Rose Tara , Alfaro-Laganse Carmela , Badri Suad , Smith Kathy , Katz Becky 
Published: December 2024

IntroductionDeclared a global pandemic by the World Health Organization (WHO) in March 2020, the COVID-19 virus and attendant patchwork of local, regional, and national government-initiated public health responses to it unexpectedly opened possibilities for greater access to culture for disabled and chronically ill people in ways that were unimagined in pre-pandemic times. During the “emergency” period of the pandemic, the fields of critical disability studies and aging studies independently demonstrated the importance and value of shifting to digital technologies for disabled people and older adults respectively; however, to date, little scholarship has considered the value of digital technologies for older adults aging with and into disabilities beyond pandemic time.MethodsInformed by the theoretical insights of scholarship exploring critical access and the aging-disability nexus, this paper draws from empirical data collected during Phase 2 of Direct[Message]: Digital Access to Artistic Engagement, a collaborative, community-based, arts-informed research project based in Southwestern Ontario (Canada). Drawing from 50 qualitative interviews with aging adults from un/under/represented communities, findings explore the intersections of older age and disability, including dynamics related to gender, sexuality, migration, size, race/ethnicity, and other differences, as these relate to access to and enjoyment of creative spaces before, during, and “after” the COVID-19 pandemic.ResultsResults show that older adults aging with/into disabilities in Southwestern Ontario express an overwhelming desire and even urgent need to access interactive arts programming from the relatively safe spaces of their homes both within and outside pandemic time.DiscussionAs the normative world pushed for a return to ableist normative life in 2022, a year marked by “severe” rates of the highly infectious Omicron variant and the loss of effective public measures, such as community masking and widely available testing, participants described the need for continued access to creative and social participation via remote options that sidestepped socially exclusive and physically inaccessible spaces. Findings indicate a need for increased investment in digital arts programming for older adults aging with/into disabilities.
Protective effects of Pelargonium graveolens (geranium) oil against cefotaxime-induced hepato-renal toxicity in rats
Authors: Azzam Shaimaa M. , Elsanhory Heba M. A. , Abd El-Slam Ahmed H. , Diab Marwa S. M. , Ibrahim Halima Mohamed , Yousef Abdalrahman Mohammed , Sabry Fatma Mahmoud , Khojah Ebtihal Y. , Bokhari Somaiah A. , Salem Gad Elsayed Mohamed , Zaghloul Marwa Saad 
Published: December 2024

Cefotaxime is a broad-spectrum antibiotic targeting Gram-negative bacteria used for diverse infections, but it can be toxic to the stomach, liver, and kidneys. This study explored the protective effects of geranium oil against cefotaxime-induced hepatotoxicity and nephrotoxicity in rats, employing biochemical, histopathological, and immunohistochemical evaluations. Thirty rats were divided into five groups of six animals each one. Group 1 received orally normal saline for 14 days, Group 2 was given orally 2.5% DMSO for 14 days, Group 3 received cefotaxime (200 mg/kg/day IM) for 14 days, Group 4 received with cefotaxime (200 mg/kg/day IM) and geranium oil (67 mg/kg b. w./day orally in DMSO) for 14 days, and Group 5 received geranium oil alone (67 mg/kg b. w./day orally in DMSO) for 14 days. Geranium oil significantly reduced cefotaxime-induced damage, evidenced by lower serum levels of liver enzymes (AST, ALT), renal markers (urea, creatinine), and other indicators (alkaline phosphatase, TNF-alpha, IL-1Beta, MAPK, nitric oxide, MDA). It also increased levels of protective tissue biomarkers such as NrF2, albumin, catalase, Beclin 1, and reduced glutathione (GSH). Histopathological and immunohistochemical analyses revealed significant protective effects in liver and renal tissues in rats treated with Geranium oil. These results suggest that Geranium oil is effective in mitigating cefotaxime-induced hepatotoxicity and renal toxicity.
An Efficient pH Detector for Water Contamination Based on Mach–Zehnder Interferometer Application
Authors: Rico-Mendez Mario Angel , Selvas Romeo , Kharissova Oxana V. , Toral-Acosta Daniel , Puente-Ramirez Norma Patricia , Chapa-Garcia Ricardo , Gonzalez-Roque Abraham Antonio 
Published: December 2024

This paper presents a pH sensor with a Mach–Zehnder Interferometer (MZI) that operates in solutions of 4.0, 7.0, and 10.0. The sensor device consists of two tapered sections with dimensions of 1 mm/1 mm/1 mm for down-taper, waist-length, and up-taper, respectively, with a separation of 10 mm. The diameter of the waist is 40 μm. This work includes the experimental evaluation of an MZI fiber optic pH sensor at 1559 nm, where 1559 nm represents a specific wavelength chosen for its optimal sensitivity in evaluating the sensor pH detection performance. It is not the central wavelength of the optical fiber, but one of the minimal values selected to enhance the interaction between the evanescent field and the sample, ensuring the reliable detection of pH variations. These sensor dimensions and the functionalized solution of multi-walled carbon nanotubes (MWCNTs) increase the detection of pH in dyes used in the textile industry. Alizarin is a strong anionic red dye that is part of the anthraquinone dye group. The experimental results demonstrated effective detection of pH levels in water contamination involving dye. This development could resolve the problem with Alizarin. The simple fabrication, low cost, and stability of the optical response make this sensor relevant for pH measurements in water contamination.
Hubungan penerapan metode kanguru dengan stabilisasi suhu tubuh pada bayi berat badan lahir rendah
Authors: Marliana Mala Tri , Russiska Russiska , Rohaeni Nani 
Published: December 2024

Latar Belakang: Angka terjadinya BBLR di Indonesia masih relatif tinggi, di Provinsi Jawa Barat angka kejadian BBLR tahun 2021 sebanyak 22.240 kasus. RSU Islami Mutiara Bunda terletak di Kecamatan Tanjung Kabupaten Brebes pada tahun 2021 terdapat 314 kasus. Bayi dengan BBLR memiliki resiko kematian 20 kali lebih besar dibandingkan bayi dengan berat badan normal.Metode: Metode yang digunakan adalah analitik dengan desain cross sectional. Teknik pengambilan sampel dilakukan secara accidental sampling, dengan jumlah responden sebanyak 33 kasus. Analisis statistik dilakukan dengan menggunakan Chi – Square untuk analisis bivariat.Hasil: Sebagian besar responden yang melakukan metode kanguru yaitu sebanyak 20 orang (60,6%). Sebagian besar stabilitas suhu tubuh bayi stabil sebanyak 25 responden (75,8%). Hubungan antara penerapan metode kanguru dengan stabilisasi suhu tubuh diperoleh nilai Pvalue 0,003 < 0,05.Kesimpulan: Terdapat hubungan antara penerapan metode kanguru dengan stabilisasi suhu tubuh bayi berat badan lahir rendah.
Проблема лоббизма в современном российском обществе
Authors: ШИТИКОВ М.В. 
Published: December 2024

В статье поднимается тема лоббизма в современном обществе. Анализируются его сущность и виды. Рассматривается вопрос о необходимости регулирования лоббистской деятельности на законодательном уровне.
The article raises the topic of lobbyism in modern society. Its essence and types are analyzed. The question of the need to regulate lobbying activities at the legislative level is being considered.