bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supersymmetry anomalies in $$ \mathcal{N}=1 $$ conformal supergravity
Authors: Papadimitriou Ioannis 
Published: April 2019

Abstract
We solve the Wess-Zumino consistency conditions of $$ \mathcal{N}=1 $$
N
=
1
off-shell conformal supergravity in four dimensions and determine the general form of the superconformal anomalies for arbitrary a and c anomaly coefficients to leading non trivial order in the gravitino. Besides the well known Weyl and R-symmetry anomalies, we compute explicitly the fermionic $$ \mathcal{Q} $$
Q
- and $$ \mathcal{S} $$
S
-supersymmetry anomalies. In particular, we show that $$ \mathcal{Q} $$
Q
-supersymmetry is anomalous if and only if R-symmetry is anomalous. The $$ \mathcal{Q} $$
Q
- and $$ \mathcal{S} $$
S
-supersymmetry anomalies give rise to an anomalous supersymmetry transformation for the supercurrent on curved backgrounds admitting Killing spinors, resulting in a deformed rigid supersymmetry algebra. Our results may have implications for supersymmetric localization and supersymmetry phenomenology. Analogous results are expected to hold in dimensions two and six and for other supergravity theories. The present analysis of the Wess-Zumino consistency conditions reproduces the holographic result of arXiv:1703.0429 and generalizes it to arbitrary a and c anomaly coefficients.
Bounds and prospects for stable multiply charged particles at the LHC
Authors: Jäger Sebastian , Kvedaraitė Sandra , Perez Gilad , Savoray Inbar 
Published: April 2019

AbstractColored and colorless particles that are stable on collider scales and carry exotic electric charges, so-called Multiply-Charged Heavy Stable Particles (MCHSPs), exist in extensions of the Standard Model, and can include the top partner(s) in solutions of the hierarchy problem. To obtain bounds on color-triplets and color-singlets of charges up to |Q| = 8, we recast searches for signatures of two production channels: the “open” channel — where the particles are pair-produced above threshold, and are detectable in dedicated LHC searches for stable multiply charged leptons, and the “closed” channel — where a particle-antiparticle pair is produced as a bound state, detectable in searches for a diphoton resonance. We recast the open lepton searches by incorporating the relevant strong-interaction effects for color-triplets. In both open and closed production, we provide a careful assessment of photon-induced processes using the accurate LUXqed PDF, resulting in substantially weaker bounds than previously claimed in the literature for the colorless case. Our bounds for colored MCHSPs are shown for the first time, as the LHC experiments have not searched for them directly. Generally, we obtain nearly charge-independent lower mass limits of around 970 GeV (color-triplet scalar), 1200 GeV (color-triplet fermion), and 880-900 GeV (color-singlet fermion) from open production, and strongly charge-dependent limits from closed production. In all cases there is a cross-over between dominance by open and closed searches at some charge. We provide prospective bounds for$$ \sqrt{s}=13 $$s=13TeV LHC searches at integrated luminosities of 39.5 fb−1, 100 fb−1, and 300 fb−1. Moreover, we show that a joint observation in the open and the closed channels allows to determine the mass, spin, color, and electric charge of the particle.
A bound on massive higher spin particles
Authors: Afkhami-Jeddi Nima , Kundu Sandipan , Tajdini Amirhossein 
Published: April 2019

Abstract
According to common lore, massive elementary higher spin particles lead to inconsistencies when coupled to gravity. However, this scenario was not completely ruled out by previous arguments. In this paper, we show that in a theory where the low energy dynamics of the gravitons are governed by the Einstein-Hilbert action, any finite number of massive elementary particles with spin more than two cannot interact with gravitons, even classically, in a way that preserves causality. This is achieved in flat spacetime by studying eikonal scattering of higher spin particles in more than three spacetime dimensions. Our argument is insensitive to the physics above the effective cut-off scale and closes certain loopholes in previous arguments. Furthermore, it applies to higher spin particles even if they do not contribute to tree-level graviton scattering as a consequence of being charged under a global symmetry such as ℤ2. We derive analogous bounds in anti-de Sitter space-time from analyticity properties of correlators of the dual CFT in the Regge limit. We also argue that an infinite tower of fine-tuned higher spin particles can still be consistent with causality. However, they necessarily affect the dynamics of gravitons at an energy scale comparable to the mass of the lightest higher spin particle. Finally, we apply the bound in de Sitter to impose restrictions on the structure of three-point functions in the squeezed limit of the scalar curvature perturbation produced during inflation.
Modelling the dynamic effects of elective hospital admissions on emergency levels in England
Authors: Jimenez-Martin Sergi , Nicodemo Catia , Redding Stuart 
Published: April 2019

Abstract
In England as elsewhere, policy makers are trying to reduce the pressure on costs due to rising hospital admissions by encouraging GPs to refer fewer patients to hospital specialists. This could have an impact on elective treatment levels, particularly procedures for conditions which are not life-threatening and can be delayed or perhaps withheld entirely. This study attempts to determine whether cost savings in one area of publicly funded health care may lead to the increases in cost in another and therefore have unintended consequences by offsetting the cost-saving benefits anticipated by policy makers. Using administrative data from Hospital Episode Statistics in England, we estimate dynamic fixed effects panel data models for emergency admissions at Primary Care Trust and Hospital Trust levels for the years 2004–2013, controlling for a group of area-specific characteristics and other secondary care variables. We find a negative link between current levels of elective care and future levels of emergency treatment. This observation comes from a time of growing admissions, and there is no guarantee that the link between emergency and elective activity will persist if policy is effective in reducing levels of elective treatment, but our results suggest that the cost-saving benefits to the NHS from reducing elective treatment are reduced by between 5.6 and 15.5% in aggregate as a consequence of increased emergency activity.
Realization of high-efficiency and high-output characteristics of magnetic power generators using single-phase angle transformation and three-phase six-wire winding
Authors: Lin Ching-Chuan , Chen Chang-Ren 
Published: April 2019

AbstractTaiwan’s electricity consumption during summer increases significantly owing to the abnormal climatic changes caused by the greenhouse effect. An expedient strategy to develop a high-efficiency magnetic power generator can address the existing problem of power shortage in Taiwan. The magnetic power generator uses the force between the polarity of the magnet and the induced magnetic field of the coil to generate suction and thrust forces, which are generated when a magnet enters and leaves the coil, respectively, and can reduce the motor power consumption to achieve an energy saving effect. From the viewpoint of single-phase magnetic power generators, an angle transformation arrangement is used to achieve a positive power output to maximize the power efficiency, and three-phase power generation is used to maximize the output, where 8 magnets and 12 six-wire wound coils are used in conjunction with a delta or Y connection to achieve three-phase output. Each phase is 120° out of phase and each phase has 4 coils that generate power per revolution simultaneously. The high output characteristic enables the use of the three-phase magnetic power generators in several industrial applications. Herein, for a single-phase power generator, 8 magnets and 10 wires were used in an angle transformation arrangement, which achieved an output efficiency of up to 129.7%, whereas the three-phase power generator with 8 magnets and 12 six-wire wound coils with a diameter of 0.4 mm were used in conjunction with a delta or Y connection and achieved, which achieved an output efficiency of up to 82%, indicating that both these generators can be used for emergency power generation in homes, factories, or hospitals.
Safety and clinical activity of the Notch inhibitor, crenigacestat (LY3039478), in an open-label phase I trial expansion cohort of advanced or metastatic adenoid cystic carcinoma
Authors: Even C. , Lassen U. , Merchan J. , Le Tourneau C. , Soria J-C , Ferte C. , Ricci F. , Diener J. T. , Yuen E. , Smith C. , Oakley G. J. , Benhadji K. A. , Massard Christophe 
Published: April 2019

SummaryBackgroundDeregulated Notch signaling is implicated in multiple cancers. The phase I trial (I6F-MC-JJCA) investigated the safety and anti-tumor activity of crenigacestat (LY3039478), a selective oral Notch inhibitor, in an expansion cohort of patients with adenoid cystic carcinoma (ACC) who received the dose-escalation-recommended phase 2 dose (RP2D), established previously (Massard C, et al.,Annals Oncol2018, 29:1911–17).MethodsPatients with advanced or metastatic cancer, measurable disease, ECOG-PS ≤1, and baseline tumor tissue were enrolled. Primary objectives were to identify a safe RP2D, confirm this dose in expansion cohorts, and document anti-tumor activity. Secondary objectives included safety and progression-free survival (PFS). The ACC expansion cohort received the RP2D regimen of 50 mg crenigacestat thrice per week in a 28-day cycle until disease progression or other discontinuation criteria were met.ResultsTwenty-two patients with ACC were enrolled in the expansion cohort (median age of 60 years). Median treatment duration was 3 cycles with 6 patients remaining on treatment. There were no objective responses; 1 (5%) patient had an unconfirmed partial response. Disease control rate was 73% and 4 patients had stable disease ≥6 months. Median PFS was 5.3 months (95%CI: 2.4-NE)) for the 22 patients; and 7.7 months (95%CI: 4.0-NR) and 2.4 months (95%CI: 1.1-NE) in the subgroup of patients in second-line (n = 7) or ≥ third-line (n = 9), respectively. Frequent treatment-related-adverse events (all grades) included diarrhea, fatigue, vomiting, decreased appetite, dry mouth, and dry skin. There were no new safety signals.ConclusionThe crenigacestat RP2D regimen induced manageable toxicity and limited clinical activity, without confirmed responses, in heavily pretreated patients with ACC.
Can your advertising really buy earned impressions? The effect of brand advertising on word of mouth
Authors: Lovett Mitchell J. , Peres Renana , Xu Linli 
Published: April 2019

Abstract
Paid media expenditures could potentially increase earned media exposures such as social media posts and other word-of-mouth (WOM). However, academic research on the effect of advertising on WOM is scarce and shows mixed results. We examine the relationship between monthly Internet and TV advertising expenditures and WOM for 538 U.S. national brands across 16 categories over 6.5 years. We find that the average implied advertising elasticity on total WOM is small: 0.019 for TV, and 0.014 for Internet. On the online WOM (measured volume of brand chatter on blogs, user-forums, and Twitter), we find average monthly effects of 0.008 for TV and 0.01 for Internet advertising. Even the categories that have the strongest implied elasticities are only as large as 0.05. Despite this small average effect, we do find that advertising in certain events may produce more desirable amounts of WOM. Specifically, using a synthetic control approach, we find that being a Super Bowl advertiser causes a moderate increase in total WOM that lasts 1 month. The effect on online WOM is larger, but lasts for only 3 days. We discuss the implications of these findings for managing advertising and WOM.
The structure of audio–visual consciousness
Authors: Skrzypulec Błażej 
Published: April 2019

AbstractIt is commonly believed that human perceptual experiences can be, and usually are, multimodal. What is more, a stronger thesis is often proposed that some perceptual multimodal characters cannot be described simply as a conjunction of unimodal phenomenal elements. If it is the case, then a question arises: what is the additional mode of combination that is required to adequately describe the phenomenal structure of multimodal experiences? The paper investigates what types of audio–visual experiences have phenomenal character that cannot be analysed as a mere conjunction of visual and auditory elements; and how can we properly characterise the required, additional mode of perceptual combination. Three main modes of combination are considered: (a) instantiation, (b) parthood, and (c) grouping. It is argued that some phenomena involving intermodal relations, like spatial and temporal ventriloquism, can be analysed in terms of audio–visual, perceptual grouping. On the other hand, cases of intermodal binding need a different treatment. Experiences involving audio–visual binding should be analysed as experiences presenting objects or events which instantiate, or which have a proper part instantiating, both visually and auditorily determined properties.
Stepwise Fabrication of Co-Embedded Porous Multichannel Carbon Nanofibers for High-Efficiency Oxygen Reduction
Authors: Tang Zeming , Zhao Yingxuan , Lai Qingxue , Zhong Jia , Liang Yanyu 
Published: April 2019

Abstract
A novel nonprecious metal material consisting of Co-embedded porous interconnected multichannel carbon nanofibers (Co/IMCCNFs) was rationally designed for oxygen reduction reaction (ORR) electrocatalysis. In the synthesis, ZnCo2O4 was employed to form interconnected mesoporous channels and provide highly active Co3O4/Co core–shell nanoparticle-based sites for the ORR. The IMC structure with a large synergistic effect of the N and Co active sites provided fast ORR electrocatalysis kinetics. The Co/IMCCNFs exhibited a high half-wave potential of 0.82 V (vs. reversible hydrogen electrode) and excellent stability with a current retention up to 88% after 12,000 cycles in a current–time test, which is only 55% for 30 wt% Pt/C.
Testing of brick clay modifications as a raw material for building ceramic products
Authors: Šál Jiří 
Published: April 2019

Brick clay is nowadays modified by various procedures to achieve the best properties when used for building ceramic products. In the treatment of these clays, the properties are regulated by changing the quantity of water, sharpening, lightening, venting, settling, using additives, but also by consistent homogenization, crushing, grinding and mixing.
This article compares several clay bricks before and after treatment and also compares them with ceramic clay. Comparative parameters are bulk density, porosity, water absorption, compressive strength and flexural strength, long-term changes in burning and weight loss by burning.
Tyranny, Communism, and U.S. Policy in Equatorial Guinea, 1968–1979*
Authors: Jensen Geoffrey 
Published: April 2019

Abstract
This study of Washington’s dealings with Equatorial Guinea under the rule of one of modern Africa’s most brutal dictators, Francisco Macías Nguema, analyzes US perceptions and policies relating to communist intervention, human rights, and related geopolitical issues during the Nixon, Ford, and Carter presidencies. It also sheds light on the relationships and conflicts between the Soviet Union, China, and Cuba in Africa. In addition, it offers new perspectives on Cuba’s close ties to the dictatorship of Francisco Macías Nguema and on the possible role of international actors in his downfall in 1979.
Pollen Diet Composition Impacts Early Nesting Success in Queen Bumble Bees Bombus impatiens Cresson(Hymenoptera: Apidae)
Authors: Watrous Kristal M , Duennes Michelle A , Woodard S Hollis 
Published: April 2019

Abstract
Bumble bees are generalist pollinators that typically collect floral rewards from a wide array of flowering plant species. Among the greatest threats to wild bumble bee populations worldwide, many of which are declining, is a loss of floral resource abundance and diversity in the landscapes they inhabit. We examined how composition of pollen diet impacts early nesting success in laboratory-reared queens of the bumble bee Bombus impatiens. Specifically, we provided queens and their young nests with one of three pollen diets, each of which was dominated by a single pollen type, and explored how this diet treatment influenced the length of time until queens initiated nests, total counts of brood in the nest at the end of the experiment (8 wk later), and the size and weight of adult offspring produced. We found that the amount of later-stage brood (pupae and/or adults) produced by recently-initiated nests was strongly impacted by pollen diet. For example, on average 66% fewer later-stage brood were found in nests provided with the Cistus pollen Linnaeus (Cistaceae), relative to the predominantly Asteraceae pollen. This finding suggests that particular pollen diet compositions may delay larval growth, which delays colony development and may ultimately be detrimental for young nests. This study sheds light on how one of the leading stressors for bumble bees (nutritional stress) may negatively impact populations through its influence on brood production during the nest-founding stage of the colony cycle.
Who watches the WATCHMAN™? A case of incomplete endothelialization at 3 years after device implantation
Authors: McIvor Felicity , Wall Douglas 
Published: April 2019

Abstract
WATCHMAN™ is a left atrial appendage (LAA) occlusion device used to prevent thromboembolism in patients with atrial fibrillation. Endothelialization of the device is required to completely occlude the LAA. Prior to endothelialization, the device is thrombogenic. The duration of dual-antiplatelet therapy after device insertion is based on animal studies demonstrating endothelialization at 3 months. A 73-year-old man presented with symptomatic severe mitral regurgitation 3 years after the WATCHMAN device was implanted. During mitral valve repair, we found that the WATCHMAN device was not endothelialized. The device was removed and the LAA was ligated after repair of the mitral valve. The long-term incidence and clinical significance of incomplete endothelialization after LAA-occlusion must be investigated. Postimplantation and perioperative antiplatelet and anticoagulation protocols require re-evaluation. The potential role of thoracoscopic epicardial LAA clipping must be considered.
Biochemical insights into the recombinant 10-deacetylbaccatin III-10-β-O-acetyltransferase enzyme from the Taxol-producing endophytic fungus Lasiodiplodia theobromae
Authors: Sah Balendra , Subban Kamalraj , Jayabaskaran Chelliah 
Published: April 2019

ABSTRACT
10-deacetylbaccatin III-10-β-O-acetyltransferase (DBAT) is a key rate-limiting enzyme of the Taxol biosynthetic pathway, which is uncharacterized in Taxol-producing endophytic fungi. Here, an open reading frame of DBAT was cloned from the Taxol-producing endophytic fungus Lasiodiplodia theobromae (LtDBAT). The LtDBAT enzyme was heterologously expressed and purified by the affinity and gel filtration chromatography methods. The molecular weight of the purified protein was 49 kDa and its identity was confirmed by western blot. The purified LtDBAT enzyme was capable of catalyzing 10-deacetylbaccatin III into baccatin III, as shown by liquid chromatography–mass spectroscopy. The mass spectra of baccatin III were identical to the authentic baccatin III. The LtDBAT enzyme was characterized and the kinetic parameters of catalysis were determined. In addition, localization of LtDBAT was performed by using confocal microscopy and the result showed that the enzyme was localized in lipid droplets. Together, this study provides biochemical insights into the fungal recombinant DBAT enzyme that is involved in the Taxol biosynthetic pathway. In the near future, engineering of the LtDBAT enzyme and the Taxol biosynthetic pathway in endophytic fungi could be an eco-friendly and economically feasible alternative source for production of Taxol and its precursors.
Functional coupling in the evolution of suction feeding and gill ventilation of sculpins (Perciformes: Cottoidei)
Authors: Farina S C , Knope M L , Corn K A , Summers A P , Bemis W E 
Published: April 2019

AbstractSuction feeding and gill ventilation in teleosts are functionally coupled, meaning that there is an overlap in the structures involved with both functions. Functional coupling is one type of morphological integration, a term that broadly refers to any covariation, correlation, or coordination among structures. Suction feeding and gill ventilation exhibit other types of morphological integration, including functional coordination (a tendency of structures to work together to perform a function) and evolutionary integration (a tendency of structures to covary in size or shape across evolutionary history). Functional coupling, functional coordination, and evolutionary integration have each been proposed to limit morphological diversification to some extent. Yet teleosts show extraordinary cranial diversity, suggesting that there are mechanisms within some teleost clades that promote morphological diversification, even within the highly integrated suction feeding and gill ventilatory systems. To investigate this, we quantified evolutionary integration among four mechanical units associated with suction feeding and gill ventilation in a diverse clade of benthic, primarily suction-feeding fishes (Cottoidei; sculpins and relatives). We reconstructed cottoid phylogeny using molecular data from 108 species, and obtained 24 linear measurements of four mechanical units (jaws, hyoid, opercular bones, and branchiostegal rays) from micro-CT reconstructions of 44 cottoids and 1 outgroup taxon. We tested for evolutionary correlation and covariation among the four mechanical units using phylogenetically corrected principal component analysis to reduce the dimensionality of measurements for each unit, followed by correlating phylogenetically independent contrasts and computing phylogenetic generalized least squares models from the first principle component axis of each of the four mechanical units. The jaws, opercular bones, and branchiostegal rays show evolutionary integration, but the hyoid is not positively integrated with these units. To examine these results in an ecomorphological context, we used published ecological data in phylogenetic ANOVA models to demonstrate that the jaw is larger in fishes that eat elusive or grasping prey (e.g., prey that can easily escape or cling to the substrate) and that the hyoid is smaller in intertidal and hypoxia-tolerant sculpins. Within Cottoidei, the relatively independent evolution of the hyoid likely has reduced limitations on morphological evolution within the highly morphologically integrated suction feeding and gill ventilatory systems.