bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross Cultural Validation of Oral Health Index Profile for Temporomandibular Disorders in Spanish Speaking Population
Authors: Fernando Oyarzo Juan , Manriquez Carolina , Durham Justin 
Published: November 2024

ABSTRACTObjectivesStructured patient‐centred assessment is critical for improving care. OHIP‐TMDs are a validated English‐language outcome measure for temporomandibular disorders (TMD) which evaluates the biopsychosocial impact of TMD. Due to language and cultural changes, the original instrument's phrasing of its items may change when translated to Spanish. This study cross‐culturally adapted and validated OHIP‐TMDs for Spanish‐speaking individuals with TMD.MethodsOHIP‐TMDs was forward‐backward translated into Spanish (OHIP‐TMDs‐Sp) and cross‐culturally adapted to a Hispanic population with TMD (Diagnostic Criteria for TMD n = 154) according to international norms. All patients completed the OHIP‐TMDs‐Sp, the Graded Chronic Pain Scale (GCPS), and Jaw Functional Limitation Scale (JFLS‐20). A subsample (n = 30) recompleted the OHIP‐TMDs‐Sp after a 3‐week washout to measure test–retest reliability using an intra‐class correlation coefficient (ICC 2.1). OHIP‐TMDs‐Sp, JFLS‐20, and GCPS were analysed for convergent validity and internal consistency.ResultsThe sample with articular and muscular TMD diagnoses was 85.7% female with a mean age of 29.5. (SD 9.01). OHIP‐TMDs‐Sp had high internal reliability (Cronbach's Alpha = 0.95) and good test–retest reliability (ICC = 0.82; 95% CI = 0.57–0.93). In terms of convergent validity, the OHIP‐TMDs‐Sp demonstrated moderate to large positive correlations with the total JLFS‐20 score (ρ = 0.72; p < 0.01), Mastication (ρ = 0.68; p < 0.01), Communication (ρ = 0.68; p < 0.001), as well to GCPS disability score (ρ = 0.59; p < 0.01), and characteristic pain intensity (ρ = 0.69; p < 0.01).ConclusionsThe total score of OHIP‐TMDs‐Sp is reliable for assessing quality‐of‐life in Spanish‐speaking TMD patients.
Genome‐Wide Association Study of Temporomandibular Disorder‐Related Pain in Finnish Populations
Authors: Leppilahti J. M. , Knuutila J. , Pesonen P. , Vuollo V. , Männikkö M. , Karjalainen M. K. , Suominen A. L. , Sipilä K. 
Published: November 2024

ABSTRACTBackgroundTemporomandibular disorders (TMD) are multifactorial musculoskeletal pain and dysfunctions in temporomandibular joints (TMJs) and masticatory muscles. Genetic factors play a role in TMD‐related pain, but only a few genome‐wide association studies (GWAS) have been conducted.ObjectiveThe aim of this GWAS was to explore genetic factors associated with painful TMD in Finnish populations.MethodsData from two epidemiological surveys, the Northern Finland Birth Cohort 1966 (NFBC1966) and the Health 2000 Survey in Finland, including altogether 468 cases and 6833 controls, were used. Case definition was based on pain on palpation of masticatory muscles and/or TMJs. GWASs of the whole data and stratified by sex were conducted from both cohorts using additive models, followed by meta‐analysis of the two cohorts. Replications of the previously reported TMD risk loci (rs73460075, DMD; rs4794106, SGCA; rs73271865, SP4; rs60249166, RXP2; rs1531554, BAHCCI; rs5862730, OTUD4/SMAD1; rs10092633, SFRP1; rs34612513, SOX14/CLDN18; rs878962, TSPAN9) were also investigated.ResultsFour genome‐wide significant loci were found in sex‐stratified analysis of NFBC1966, including associations at three loci in males (rs1023114, PRIM2, p = 5 × 10−9; rs4244867, ALG10, p = 3 × 10−8; rs79841648, ADCYAP1, p = 4 × 10−9) and one locus in females (rs148476652, DNER, p = 4 × 10−9). However, the results could not be replicated in the Health 2000 Survey or in the meta‐analysis of these two cohorts. The previous TMD GWAS associations did not replicate in our data either.ConclusionSeveral TMD pain‐associated variants were found in sex‐stratified analysis of NFBC1966, suggesting the role of neuroendocrine stress responses and central nervous system. These findings need to be confirmed in future studies.
Weight Loss and Number of Present Teeth in Community‐Dwelling Japanese Older Adults: A Cross‐Sectional Study in Niigata
Authors: Takehara Sachiko , Ueno Masayuki , Yoshihara Akihiro , Iwasaki Masanori , Suwama Kana , Minagawa Kumiko , Narita Ichiei , Tanaka Junta , Ogawa Hiroshi , Ito Yumi 
Published: November 2024

ABSTRACTBackground and ObjectivesWeight loss is a critical health issue among the older population. This study aimed to explore the association between weight loss and oral health in older adults.MethodsWe used cross‐sectional data from the Uonuma Chronic Kidney Disease Cohort Study. The binary logistic regression models were fitted to estimate the relationship between weight loss and independent variables including the number of teeth present.ResultsThe participants included 1656 females and 1625 males. There were 1217 females (73.4%) and 1236 males (76.0%) with normal BMI (18.5 ≤ BMI < 25) in the previous year. Weight loss was determined over a 12‐month period. Individuals with normal BMI in previous year, and those with weight loss (≥ 5%) or those whom maintained a stable weight were further analysed. The regression analysis (model 3, fully adjusted) showed that females with 0 and 1–10 teeth present had a higher likelihood of losing weight (OR = 4.07; 95% CI = 1.85–8.93, OR = 2.33; 95% CI = 1.24–4.39) compared with those with 20 or more teeth. Current smokers had a higher likelihood of losing weight (OR = 3.15; 95% CI = 1.01–9.76) than lifelong abstainers. Among males, both current and previous smokers showed a higher likelihood of losing weight (OR = 4.94; 95%CI = 1.76–13.8, OR = 3.35; 95% CI = 1.29–8.68) than those who never smoked.ConclusionsThis study indicates that the number of teeth and smoking are both linked to weight loss in females. However, in males, the association between the number of teeth and weight loss may be compromised due to the high prevalence of smoking in this group.
Treatment Outcomes of Four‐Implant‐Retained Maxillary Palateless Overdenture: A 5‐Year Observational Study
Authors: Sude Asha , Schlam Kimberly K. , de Viteri Tejeda Hector Saenz , Reside Glenn J. , Sanders Anne E. , Felton David A. , De Kok Ingeborg J. 
Published: November 2024

ABSTRACTIntroductionPalateless overdentures (PLODs) provide advantages of improved taste perception and retention over conventional dentures. We aimed to evaluate 5‐year outcomes of four implant maxillary PLODs.MethodsIn this prospective observational study, edentulous participants were enrolled. A new conventional maxillary denture was prepared followed by implant placement and insertion of four implant retained maxillary PLOD. Oral health quality of life was assessed using the 49‐item Oral Health Impact Profile (OHIP‐49) at multiple intervals over 5 years along with biological and mechanical outcomes.ResultsNine patients were evaluated at year 5. The mean age was 68 years, and six of the nine patients were males. The cumulative survival rate of implants was 100% while the implant success rate was 86%. Nylon retentive replacement was the most common encountered complication noted approximately four times per patient over 5 years. From a mean OHIP‐49 severity score of 71.2 at baseline, severity scores decreased to 23.9 (p < 0.001) at year 1, denoting a clinically meaningful and statistically significant improvement in oral health quality of life. The lowered OHIP‐49 severity scores remained stable throughout 5 years of follow‐up.ConclusionFour implant supported maxillary overdenture appears to have good patient perceived, biological and mechanical outcomes over 5 years. Fully powered studies are needed to replicate these findings.
Trial Waste in Hyaluronic Acid‐Related Randomised Controlled Trials
Authors: Chen Hongrui , Yu Qinqi , Huang Zening , Sun Bin , Hua Chen , Lin Xiaoxi 
Published: November 2024

ABSTRACTBackgroundA notable obstacle in applying the findings of hyaluronic acid (HA)‐related randomised controlled trials (RCTs) to real‐world patient treatment is trial waste (TW). To date, the extent of TW in RCTs for HA is not clear.ObjectivesTo analyse the extents of TW within HA‐RCTs and identify protective factors against TW.MethodsIn July 2024, we searched the ClinicalTrials database using the ‘hyaluronic acid’ as keyword. We documented the data available and then explored PubMed and Scopus for the publication status. Reporting adequacy was evaluated using the CONSORT checklist. Design limitations were analysed based on bias risk and whether the article referenced a relevant systematic review. Subsequently, we evaluated extent of TW (unpublished studies, insufficient reporting and design flaws).ResultsOne hundred and eighty‐four RCTs met the inclusion criteria. The analysis of TW excluded 53 RCTs completed after June 2020 that remained unpublished. Among the remaining 131 RCTs, 72 were published, 47 had adequate reporting and 19 had design limitations. Taken together, 96 RCTs (73.3%) exhibited at least one characteristic of TW. Characteristics of these RCTs included early registration (p < 0.001) and the absence of a multi‐blind approach (p = 0.007). Registration prior to 2014 (p < 0.001) and the open‐label or single‐blinding design (p = 0.003) emerged as independent risk factor for TW.ConclusionWe delineated the features of 184 HA‐related RCTs. 73.3% of the RCTs included in TW analysis exhibited TW. The diverse traits of the different TW indicators identified could serve as valuable insights for conducting future HA‐RCTs more rationally and efficiently.
Ontology and Bruxism: Do We Have Enough Information?
Authors: Manfredini Daniele , Lobbezoo Frank 
Published: November 2024

ABSTRACTThe idea of classifying and defining bruxism according to ontological principles may be interesting, but currently we just do not have enough information to label in a black or white manner the many facets of bruxism. In an era in which general knowledge on bruxism by the dental communities is surely in need of improvement, efforts to clarify the road map tracked by the current panelists who drafted the definition should be appraised carefully. The recent introduction of a standardized multidimensional evaluation system (i.e., Standardized Tool for the Assessment of Bruxism [STAB]) and a screening instrument for bruxism (i.e., BruxScreen) should be viewed as the starting points to enter a new era in the discipline of bruxism, in which non‐hierarchical and non‐preconceived approaches are used to collect data. Artificial intelligence strategies to mine data gathered with the above instruments might help building predictive models along the etiology‐status‐consequences trajectory, as recently suggested in a model for awake bruxism metrics. Until then, proposals to adopt ontological principles to classify bruxism will be merely based on speculations rather than on facts.
Competing Models of the Structure of Subjective Well‐Being: Have All Won and Must All Have Prizes?
Authors: Jovanović Veljko 
Published: November 2024

ABSTRACTObjectiveThe tripartite model of subjective well‐being (SWB) posits three components: positive affect, negative affect, and life satisfaction. The fundamental issue regarding the structure of SWB and the meaning of the general SWB factor remains unresolved.MethodsAcross three studies and six samples (total N = 9304), we evaluated competing models of SWB and tested the criterion‐related validity of SWB components operationalized within different models. In addition to a standard confirmatory factor analysis (CFA) and bifactor‐CFA, we used exploratory structural equation modeling (ESEM) and bifactor‐ESEM approaches. Latent factor models were applied to examine the nomological network of SWB in relation to several external criteria (e.g., positive expectations, depression, and anxiety).ResultsWe found evidence supporting the three‐factor and bifactor‐ESEM models of SWB. The meaning and interpretability of the general and specific factors of SWB were found to depend on the indicators used to assess affective well‐being. Several issues concerning the bifactor‐CFA model were identified. Both the general and specific factors of SWB exhibited meaningful and interpretable nomological networks.ConclusionsThe structure of SWB, the value of incorporating a general factor, and the nature of general and specific SWB factors depend on the instruments used to measure SWB.
Dynamic policy in the presence of social norms
Authors: Hintermann Beat , Lange Andreas 
Published: November 2024

AbstractIndividual actions can depend on prevailing social norms. We investigate how optimal policy to promote pro‐social action should exploit the underlying social dynamics. We develop a dynamic model of prosocial action in which conformist consumers repeatedly choose whether to engage in some prosocial activity. Whereas individual behavior is not observed, the overall participation rate in the previous period is common knowledge. We demonstrate how conformity can lead to multiple steady states and how their selection depends on starting conditions and discount factors. We further show that the optimal subsidy path can be non‐monotonic and can decrease before reaching the steady state‐level. Our model thus provides a rationale for introductory subsidies to promote environmentally friendly behavior from a behavioral perspective.
Leaving Haredi Judaism: Coping Resources and Perceived Social Support During Community Transitions and Religious Disaffiliation
Authors: Erhard Maria C. 
Published: November 2024

AbstractNavigating transitions across community boundaries, such as former Haredim leaving their covenantal communities of origin to integrate into mainstream society, is a widespread phenomenon with profound societal implications. This study investigates the impact of current community affiliation and perceived social support on the sense of coherence (SOC) and community sense of coherence (ComSOC) coping resources of former Haredim. Conducted in 2022, the study surveyed 147 ex‐Haredim in Israel. Findings reveal that perceived social support and strength of community affiliation predict higher SOC and ComSOC levels throughout the disaffiliation process. ComSOC shows greater sensitivity to influence than general SOC and is its strongest predictor among the studied variables. Other significant predictors are involvement in the ex‐Haredim community, years since leaving, and family disconnection. In its salutogenic quality and focus on coping resources, this study offers insights for supporting individuals navigating disaffiliation challenges and similarly profound change processes.
Bias is persistent: Sequencing case information does not protect against contextual bias in criminal risk assessment
Authors: Oberlader Verena , Verschuere Bruno 
Published: November 2024

AbstractPurposeA large body of research indicates that bias is an inherent part of human information processing. This way, bias affects all disciplines that rely on human judgements, such as forensic psychological assessment, including criminal risk evaluation. Although there is a lack of empirical studies, scholars recommend considering case information sequentially beginning with the most relevant information to reduce the effect of potentially biasing task‐irrelevant contextual information.MethodsWe ran a preregistered experimental study to test, first, whether task‐irrelevant information results in bias effects when people use criminal risk assessment tools, and second, whether such bias could be reduced by sequencing case information according to its prognostic relevance. We collected data of 308 informed lay participants instructed to apply an empirical actuarial risk scale based on a case vignette.ResultsResults showed that task‐irrelevant information biased risk assessment. Yet, sequencing case information did not protect against it.ConclusionsConsidering various boundary conditions (e.g., overconfidence in the accuracy of one's own assessment and other sources of bias), we discuss challenges to mitigate the biasing effect of task‐irrelevant information.
Local Participatory Development Models For Postwar Reconstruction in Yemen
Authors: Orkaby Asher , Al‐Ahmadi Afrah 
Published: November 2024

AbstractThe humanitarian crisis that has come to dominate public perception of Yemen since 2015 has left the country's social and civil infrastructure in major disrepair. Postwar recovery and reconstruction will be an essential component of long‐term stability in the Persian Gulf and Red Sea subregions. The unchecked distribution of large sums of foreign aid to postwar Yemen has the potential to perpetuate the country's underlying political conflicts without substantively contributing to its much‐needed economic development. Similarly, a top‐down approach that privileges foreign donors is likely to encounter political and logistical obstacles and may end up devolving into a divisive patronage system. The solution to some of these obstacles may be found in localizing the distribution of development aid, which relies on existing networks in the reconstruction of economic infrastructure. Yemen's history of community‐driven development can be the key to a sustainable post‐conflict future.
Early diagnosis of immunodeficient patients with partial albinism: The role of hair study and peripheral blood smear
Authors: Tajik Shaghayegh , Fazlollahi Mohammad Reza , Alizadeh Zahra , Badalzadeh Mohsen , Houshmand Massoud , Razaghian Anahita , Bahram Seiamak , Molitor Anne , Carapito Raphael , Shariat Mansoureh , Hamidieh Amir Ali , Behniafard Nasrin , Abdolkarimi Babak , Rostami Tahereh , Moin Mostafa , Pourpak Zahra 
Published: November 2024

AbstractBackgroundPrimary immunodeficiency diseases (inborn errors of immunity) with partial albinism are a group of autosomal recessive syndromes including Chediak Higashi Syndrome (CHS), Griscelli Syndrome type 2 (GS2), Hermansky‐Pudlak Syndromes type 2 and 10 (HPS2, HPS10), Vici syndrome and P14/LAMTOR2 deficiency.MethodsTwenty‐five patients including 10 CHS, 10 GS2, and 5 HPS2 were evaluated in this study within the last 10 years. Five cases with oculocutaneous albinism (OCA) and 5 healthy subjects without albinism were used as two control groups. Genetic analyses were performed by whole exome or panel sequencing or targeted Sanger sequencing. Subsequently, leukocyte granules in peripheral blood smear and hair shaft were examined as screening tests.ResultsGiant granules were only presented in the leukocytes cytoplasm of 10/10 CHS patients. The uneven cluster of pigments and giant melanin granules in hair samples were observed in 10/10 GS2 and 10/10 CHS patients, respectively. In both 5/5 OCA and 5/5 HPS2 patients, there were regular pigments in the middle of hair shafts. Genetic analyses were performed for all patients, revealing 7 novel variants in LYST gene for CHS patients and 4 novel variants in AP3B1 for HPS2 patients.ConclusionReceiving hematopoietic stem cell transplantation (HSCT) in a timely manner is crucial in CHS and GS2 patients; therefore, screening tests may provide a vital clue for early diagnosis in these patients. However, the final confirmation of CHS, GS2, and HPS2 disorders is done by genetic assay.
The Energy Charter Treaty: Letting the sun set on sunset clauses
Authors: Jackson Eoin 
Published: November 2024

AbstractThis article focuses on the sunset clause of the Energy Charter Treaty (ECT). The ECT is a multilateral investor‐state arbitration treaty which allows for the use of investor‐state dispute settlement (ISDS) tribunals to arbitrate challenges arising from shifts in energy policy that lead to a loss in profits for relevant energy companies. The treaty has become controversial as climate activists have alleged it is slowing down efforts to transition away from fossil fuels. Withdrawal from the ECT does not necessarily solve the alleged issues as the treaty contains a sunset clause, allowing for the provisions of the ECT to remain in force for 20 years post withdrawal. This article seeks to analyse various mechanisms and strategies for neutralising the sunset clause as part of a wider effort to ensure the ECT does not interfere with the phasing out of fossil fuels. It will be argued that such neutralisation should be possible through the use of Article 62 of the Vienna Convention on the Law of Treaties (VCLT), on the basis that there has been a fundamental change in circumstances since the inception of the treaty. This use of the rebus sic stantibus doctrine can be justified on the basis that a swift and substantial transition away from fossil fuels is now required to ensure states can meet their obligations under the Paris Agreement. This article will also explore alternatives to an Article 62 VCLT argument (i.e. a fundamental change in circumstances) that could nonetheless achieve the primary goal of ensuring that states are not bound to a pro fossil‐fuel treaty. Examples of alternatives include the insertion of a climate carve‐out to remove protections from investments that hinder climate action or the use of the defence of necessity in future ECT arbitration cases to argue that the state should not remain bound to the sunset clause. Regardless of whichever scenario is pursued by states, the article seeks to highlight that any and all efforts must be made to neutralise the sunset clause to ensure there is no interference with necessary efforts to pursue climate action.
One size does not fit all: The value of information and coexistence of rating agencies
Authors: Chung Hae Jin , Park Sojung Carol , Xie Xiaoying 
Published: November 2024

AbstractThis study investigates the production of information by multiple rating agencies and the selection of rating agencies when the value of information to buyers is heterogeneous. We argue that firms strategically choose a rating agency based on the value of information. Not only can a rating agency with a finer rating scheme than a dominant agency offer information to the market, but an agency with a coarser scheme can also provide information by serving low‐information‐value users and sellers who could not obtain a rating otherwise. This does not necessarily result in rating shopping. We tested these hypotheses using the U.S. property‐casualty insurance market, examining insurers' rating agency selections among AM Best, Demotech, and S&P. Our results indicate that the value of information to users influences both the design of rating schemes by rating agencies and the selection of rating agencies by firms. The coexistence of multiple rating agencies with different rating schemes suggests their ability to serve heterogeneous information clienteles.
Early colonization of New Caledonia by ultrasonic crickets from New Guinea (Orthoptera: Gryllidae: Eneopterinae): Historical biogeography and description of a new genus
Authors: Le Flanchec Thomas , Salazar Karen , Malem Julien , Vendanger Juliette , Poirier Eddy , Dutertre Valentin , Bonillo Céline , Chifflet‐Belle Pascaline , Legendre Frédéric , Nattier Romain , Robillard Tony 
Published: November 2024

AbstractNew Caledonian crickets of the tribe Lebinthini are renowned for their high endemicity and their use of high‐frequency calling songs. Although previous studies have found them to originate from New Guinea around 30 Ma, recent discoveries of new lineages of Lebinthini in New Caledonia and in Australia questioned this result. Here, we describe Kanakinthus koniambo Le Flanchec & Robillard gen. et sp.nov., a new genus and species endemic to New Caledonia. We also describe three new species of the endemic genus Agnothecous: A. anonymous Le Flanchec, Vendanger & Robillard sp.nov., A. borendyi Le Flanchec, Vendanger & Robillard sp.nov. and A. kwakwe Le Flanchec, Vendanger & Robillard sp.nov. We include these new taxa and the Australian Lebinthini in a molecular phylogeny of the subfamily Eneopterinae, estimate their divergence times and reconstruct their historical biogeography. Our results confirm the monophyly of the clade endemic to New Caledonia and its origin from a single colonization event from New Guinea, around 30 Ma, shortly after the archipelago completely re‐emerged in its current configuration, 34 Ma. We also infer an independent colonization of Australia by the genus Julverninthus from New Guinea, around 25 Ma.