bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perforator flap based on the third perforator of the profunda femoris artery (PFA)‐assisted closure of the free vertical posteromedial thigh (vPMT) flap donor site
Authors: Scaglioni Mario F. , Barth Andrè A. , Chen Yen‐Chou 
Published: June 2018

IntroductionThe primary closure of the vertical posteromedial thigh (vPMT) free flap donor site is very important to minimize donor site morbidity and maximize cosmetic appearance. However, sometimes due to the dimension of the defect, a vPMT flap is wider than the 8–10 cm requirement. The authors report their experience with the third perforator of the profunda femoris artery (PFA) during the vPMT free flap donor‐site closure.Patients and MethodsBetween January 2016 and December 2017, 5 patients underwent reconstruction of lower extremity (2 pts.) and head and neck (3 pts.) area with the free vPMT flaps. Attempts to close the vPMT free flap donor site directly failed due to the flaps' width (average: 11 cm) and pedicled perforator flaps based on the third perforator of the PFA at the distal thigh were harvested to close the defect primary without the use of a skin graft. The size of perforator flap based on 3rd perforator of PFA was on average 6 cm × 4 cm (ranged: 4–8 cm × 3–6 cm).ResultsIn all patients, the third perforator of the PFA was identified and the perforator diameter was on average 2.0 mm (range, 1.8–2.2 mm). All perforators were musculocutaneous and single. The dimensions of the flaps were on average 6 cm × 4 cm (range: 4 to 8 cm × 3 to 6 cm). All flaps healed uneventfully without complications and the patients were satisfied with cosmetic and functional results at 6 months follow‐up.ConclusionThe third perforator of the PFA may be an option to ensure primary closure of the PMT flap donor site, when a larger flap for reconstruction is needed with subsequent impossibility to achieve primary closure of the donor site.
Structure of a new usnic acid derivative from a deacylating Mannich reaction: NMR studies supported by theoretical calculations of chemical shifts
Authors: Nguyen Huong Giang Thi , Nguyen Vinh Ngoc , Kamounah Fadhil S. , Hansen Poul Erik 
Published: June 2018

AbstractIn a conventional Mannich reaction using piperidine, hydroxypiperidines, morpholine, and N‐methylpiperazine with usnic acid, a deacetylation was observed resulting in a substitution at C‐2, a loss of an acetyl group, and a Mannich base with a stabilized enol. The enol has a hydrogen bond to the nitrogen of the secondary amine. The structure was investigated by nuclear magnetic resonance and deuterium isotope effects on 13C chemical shifts as well as with density functional theory calculations to study the changed hydrogen bond pattern. It was found that the hydrogen bond involving the OH‐9 group in chloroform forms a strong hydrogen bond than in usnic acid itself and that this hydrogen bond becomes even stronger in the more polar solvent, dimethylsulfoxide. Tautomerism was observed in the Mannich base as demonstrated by deuterium isotope effects on chemical shifts. The position of the tautomeric equilibrium depends on the solvent, and the position of the equilibrium governs the strength of the OH‐9…O═C hydrogen bond.
Catheterization for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: A systematic review. A report from the Neuro‐Urology Promotion Committee of the International Continence Society (ICS)
Authors: Tornic Jure , Sartori Andrea M. , Gajewski Jerzy B. , Cox Ashley , Schneider Marc P. , Youssef Nadim A. , Mordasini Livio , Chartier‐Kastler Emmanuel , Bachmann Lucas M. , Kessler Thomas M. 
Published: June 2018

AimTo systematically assess all available evidence on efficacy and safety of catheterization for treating neurogenic lower urinary tract dysfunction (NLUTD) in patients with multiple sclerosis (MS).MethodsThis systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) statement. Studies were identified by electronic search of Embase, Medline, Scopus, Cochrane register (last search March 3, 2018) and by screening of reference lists and reviews.ResultsAfter screening 7′015 articles, we included four studies (one prospective and two retrospective cohort studies, one retrospective cross‐sectional study), in which a total of 445 patients were enrolled. No randomized controlled trial was available. Catheterization substantially increased quality of life, post void residual, and incontinence episodes in all included studies. Pooling of data for meta‐analysis was not possible due to the heterogeneity of reported outcomes. Adverse events were reported in two studies only. Risk of bias and confounding was intermediate.ConclusionsPreliminary data suggests beneficial effects of catheterization on the urological outcome in patients with MS. However, although intermittent and indwelling catheterization is used frequently in daily clinical practice in the MS population, the evidence base is very limited and well‐designed, properly sampled, and powered studies are urgently needed.
Strategies for conducting health research with Latinos during times of political incivility
Authors: Sage Rayna , Benavides‐Vaello Sandra , Flores Erin , LaValley Sydnie , Martyak Patrick 
Published: June 2018

AbstractAimThe current US political climate towards immigrants introduces new challenges for researchers already struggling to recruit and retain Latino participants in health research. The purpose of this work is to illuminate how current political incivility further deters participation by Latinos in research and present strategies to overcome these challenges.Design/MethodsIn this discursive piece, we describe how political incivility serves as a proxy for discrimination, discusses the impact of political incivility on health and health outcomes and explores existing knowledge of recruitment and retention strategies in the light of a current, adversely impacted health study with Latinos during the 2016 election season.ResultsFuture work should consider the critical contextual factors (including political incivility) faced by Latinos in the US, while continuing to engage in established research strategies such as increasing trust, developing strong community presence, reducing risks (real and perceived) and being thoughtful in research design and implementation.
Trends in prescription drug use during pregnancy and postpartum in Norway, 2005 to 2015
Authors: Engeland Anders , Bjørge Tone , Klungsøyr Kari , Hjellvik Vidar , Skurtveit Svetlana , Furu Kari 
Published: June 2018

AbstractPurposeTo explore trends in use of maternal medication 3 months prior to, during and 3 months after pregnancy.MethodsData on births from the Medical Birth Registry of Norway were linked to the Norwegian Prescription Database, identifying women's use of medications around pregnancy. All women giving birth in Norway during 2005 to 2015 (638 532 singleton births to 414 567 women) were included. Proportions of pregnant women using different medications in association with pregnancy, and annual relative change in medication use during 2005 to 2015, were calculated.ResultsIn Norway, 60% of pregnant women used prescription medications during pregnancy (2005‐15), increasing from 57% in 2005 to 62% in 2015. The annual relative increase was 0.9% (95% CI: 0.8‐1.0). In the first trimester, approximately 17% of the women used medications regarded as potentially teratogenic during 2005 to 2015, increasing from 15% to 19%. Overall, this proportion was higher in the first than in the second (8.9%) and third (8.0%) trimesters, and higher than in the 3 months after pregnancy (14%). The annual relative increase of medications regarded as potentially teratogenic in the first trimester was 2.5% (95% CI: 2.3‐2.7).ConclusionsThe proportion of women using potentially teratogenic medications in the first trimester of pregnancy have increased during the last decade. Clinicians need to be aware of the possibility of pregnancy when prescribing potentially teratogenic medication to women of fertile age and focus this in the consultations. The increasing trends call for the need of routine surveillance of adverse birth outcomes linked to medication use in pregnancy.
A Highly Effective, Stable Oxygen Evolution Catalyst Derived from Transition Metal Selenides and Phosphides
Authors: Bose Ranjith , Jothi Vasanth Rajendiran , Velusamy Dhinesh Babu , Arunkumar Paulraj , Yi Sung Chul 
Published: June 2018

AbstractRecently, transition metal chalcogenides and phosphides have been increasingly reported as efficient and stable oxygen evolution reaction (OER) catalysts in alkaline medium, despite the fact that they are thermodynamically unstable under highly oxidative potentials. Here the active forms of these materials are elucidated by synthesizing a hybrid catalyst, which has a metal chalcogenide in the form of CoSe2 and metal phosphide in the form of CoP—CoSe2|CoP. Both CoSe2 and CoP in the as‐prepared catalyst are completely transformed into their respective oxyhydroxides and hydroxides, which are, in fact, the true OER‐active species in alkaline medium and not the selenide and phosphide themselves. The derived oxides from the hybrid catalyst deliver an excellent OER activity by reaching a current density of 10 mA cm−2 at a low overpotential of 240 mV (vs reversible hydrogen electrode (RHE)) and a Tafel slope of 46.6 mV dec−1. The stability of the derived oxyhydroxide/hydroxide catalyst shows no appreciable deactivation during 120 h of continuous electrolysis, displaying an extraordinary operational stability.
Sibling position, gender, and family networks in Mexican and Senegalese migration
Authors: Liu Mao‐Mei , Riosmena Fernando , Creighton Mathew J. 
Published: June 2018

AbstractThis paper examines the gendered roles of sibling position and network‐derived social capital in Mexican and Senegalese international migration. We investigate how men's and women's migration decisions are associated with their position within the nuclear family before and after accounting for nuclear family migrant networks. Crucially, we also estimate how sibling network “effects” are gendered. We analyse 2 comparable household surveys in very distinct settings where family obligations may vary: the Mexican Migration Project (1998–2012) and the Migration between Africa and Europe–Senegal project (2008). Using discrete‐time event history analysis, we find that—without controls for nuclear family migrant networks—younger siblings in Mexico appear more likely to migrate than their older counterparts, whereas the opposite is true in Senegal. After we control for family migrant networks, however, older siblings in both countries and of both sexes are more likely to migrate. Despite these commonalities, migrant sibling networks appear to be gendered differently in the 2 countries. Although Mexican men are most influenced by migrant brother networks and Mexican women are most influenced by sister networks, evidence for Senegal is mixed and destination‐dependent. Brother networks motivate Senegalese men's and women's migration to Europe, whereas nearly all sibling networks, regardless of gender, influence Senegalese migration within Africa.
Reliable exponential filtering for singular Markovian jump systems with time‐varying delays and sensor failures
Authors: Liu Guobao , Xu Shengyuan , Park Ju H. , Zhuang Guangming 
Published: June 2018

SummaryThis paper deals with the problem of exponential
filtering for singular Markovian jump systems with time‐varying delays subject to sensor failures. The main objective is to design a reliable filtering such that the considered filtering error system in the presence of a time‐varying delay and sensor failures is mean‐square exponentially admissible with a specified decay rate and simultaneously satisfies an
performance. First, the delay interval is partitioned into m subintervals and a novel mode‐dependent stochastic Lyapunov‐Krasovskii functional is constructed. By using the reciprocally convex inequality in each subinterval, sufficient conditions of exponential
performance analysis are developed for the considered filtering error system. Then, based on these conditions, the existence conditions of the desired reliable filter are derived and the filter parameters are obtained. It should be mentioned that all the results presented here are not only dependent on the time delay but also dependent on the decay rate and the partitioning size. Furthermore, all the conditions are established in terms of strict linear matrix inequalities. Finally, two numerical examples are given to illustrate the less conservatism and effectiveness of the proposed methods.
Robust sampled‐data control for Itô stochastic Markovian jump systems with state delay
Authors: Chen Guoliang , Sun Jian , Xia Jianwei 
Published: June 2018

SummaryIn this paper, the problem of robust sampled‐data control for Itô stochastic Markovian jump systems (Itô SMJSs) with state delay is investigated. Using parameters‐dependent Lyapunov functionals and some stochastic equations, we give stochastic sufficient stability criteria for polytopic uncertain Itô SMJSs. As a corollary, stochastic sufficient stability criteria are given for nominal Itô SMJSs. For this two cases of Itô SMJSs, based on the obtained stochastic stability criteria, their time‐independent sampled‐data controllers are designed, respectively. Then, for designing a time‐dependent sampled‐data controller for Itô SMJSs, a parameters‐dependent time‐scheduled Lyapunov functional is developed. New stochastic sufficient stability criteria are obtained for polytopic uncertain Itô SMJSs and nominal Itô SMJSs. Furthermore, their time‐dependent sampled‐data controllers are designed, respectively. Lastly, a numerical example is provided to illustrate the effectiveness of the proposed method.
Ytterbium (III) triflate/Sodium Dodecyl Sulfate: A Versatile Recyclable and Water‐Tolerant Catalyst for the Synthesis of Bis(indolyl)methanes (BIMs)
Authors: Tornquist Bruna Luisa , de Paula Bueno Gabriel , Manzano Willig Julia Caroline , de Oliveira Isadora M. , Stefani Helio A. , Rafique Jamal , Saba Sumbal , Almeida Iglesias Bernardo , Botteselle Giancarlo V. , Manarin. Flávia 
Published: June 2018

AbstractHerein, we report the application of ytterbium(III) triflate as an efficient and versatile catalyst to synthesize bis(indolyl)methanes. The coupled products were obtained in good to excellent yields under mild reaction conditions and in a short reaction time. The catalyst was readily recovered from the reaction mixture and could be reused without any loss of activity. Moreover, the study of photophysical properties of bis(indolyl)methanes was also performed.
Biocatalyst Mediated Synthesis of Tryptanthrins Performed Under Ultrasonication
Authors: Mane Ananda H. , Patil Audumbar D. , Kamat Siddharth R. , Salunkhe Rajashri S. 
Published: June 2018

AbstractThe concomitant exploitation of two of the green chemistry tools viz., sonication and biocatalysis is reported here for the synthesis of natural alkaloid, tryptanthrin (indolo[2, 1‐b]quinazoline‐6,12‐dione). High intensity ultrasound was applied to facilitate the release of enzymes by disruption of cells of baker's yeast (Saccharomyces cerevisae) as a biocatalyst. The coupled system is an excellent instance to enhance the rate of biocatalyzed reaction and proved to be green alternative to existing methodologies for the synthesis of tryptanthrins. The present method is bestowed with merits such as mild and clean reaction conditions, operational simplicity, tolerance for a wide variety of substituents, green aspects through the avoidance of toxic metal catalysts and affords highly selective conversion with no byproducts.
Investigating the Catalytic Performance of Graphene Oxide –Polyaniline –Lignosulfonate Nanocomposite in the Synthesis of Polysubstituted Pyridines via a Four‐Component Reaction
Authors: Emami Atefeh , Ghafuri Hossein , Kenari Moghadaseh Keshvari , Maleki Ali 
Published: June 2018

AbstractIn this research, graphene oxide –polyaniline −lignosulfonate (GO‐PANI‐LS) nanocomposite was synthesized successfully and it was used as an effective recyclable catalyst for the synthesis of polysubstituted pyridines. Characterization of the prepared nanocomposite was carried out by Fourier transform infrared radiation (FT‐IR), X‐ray diffraction patterns (XRD), Energy‐dispersive x‐ray spectroscopy (EDX), Field‐emission scanning electron microscopy (FE‐SEM) and Thermogravimetric analysis (TGA). The first report of using this nanocomposite as a heterogeneous catalyst in synthesis of polysubstituted pyridines, Eco‐friendly, high catalytic activity of catalyst, simplicity of procedure, mild reaction conditions, easy recovery and considerable reusability without significant loss of performance are advantages of this method.
One‐Pot synthesis of LaMnO3/Mn3O4 Nanocomposite: Impact of Calcination Temperature on the Synergetic Effect Towards High Energy Supercapacitor Performance
Authors: Shafi Parasseri Muhammed , Nisar Naseeb , Bose Arumugam Chandra 
Published: June 2018

AbstractThe ever‐growing global energy demand and rapid depletion of fossil fuels on day‐to‐day life drive researchers to think about an alternate and efficient storage system. Supercapacitors have drawn considerable attention due to their moderate energy and power densities than batteries and capacitors respectively. Seeking to the high energy delivery with large power for prolonged cycle life, the material with excellent electrochemical behavior and extended structural stability got tremendous attraction towards the stable and sustainable storage system. Here the metal oxide of large theoretical capacitance (Mn3O4) compositing with structurally more stable perovskite oxide (LaMnO3) through a one‐pot synthesis route to form LaMnO3/Mn3O4 nanocomposite of high electrochemical performance. The one‐pot synthesize method provides a unique combination of Mn3O4 and LaMnO3, which brings out a remarkable synergetic effect and enhanced electrochemical behavior such as high energy density, large power density and long‐lasting cycle life. The composite electrode exhibits a maximum energy density of 75 Wh kg−1 at a power density of 1000 W kg−1 and the electrode could deliver a colossal power density of 15 k W kg−1 without compromising much in energy density (41.6 Wh kg−1) by symmetric cell design. From these findings, we strongly propose the one‐pot synthesized LaMnO3/Mn3O4 nanocomposite as a promising candidate for high energy supercapacitor electrode application.
Synthesis, Characterization, Antibacterial and Antioxidant Studies of Some Heterocyclic Compounds from Triazole‐Linked Chalcone Derivatives
Authors: Santosh Rangappa , Selvam Mukunthan K. , Kanekar Saptami U. , Nagaraja Gundibasappa K. 
Published: June 2018

AbstractIn the current study, an efficient synthesis of new triazole‐linked chalcone 3 a‐g scaffold was performed by multistep reaction sequence and was screened for their antibacterial activity against Pseudomonas aeruginosa, Escherchia coli, Staphylococcus aureus and Bacillus subtilis. The preliminary result revealed that 3 f exhibited a promising antibacterial activity. Furthermore, 3 f was modified at α, β‐ unsaturated carbonyl segment to isoxazoline 4 a, pyrimidines 5 a, 6 a‐b, pyrazoles 7 a‐c and cyanopyridine 8 a. Within the modified compounds 7 b (4‐nitro‐substituted pyrazole) turn to be more potent against all bacterial strains. In addition compounds, 5 a and 8 a showed promising free radical scavenging activity.
Cu(II) Complex onto a Pyridine‐Based Porous Organic Polymer as a Heterogeneous Catalyst for Nitroarene Reduction
Authors: Khatioda Rajiv , Pathak Debabrat , Sarma Bipul 
Published: June 2018

AbstractUnlike traditional catalysts, a Cu(II) catalyst incorporated onto a new pyridine based porous organic polymer linked by carboxamide functionality has been developed by impregnation method. Materials are characterized using FT‐IR, solid‐state NMR, PXRD, SEM, TEM techniques. The uniform confinement effect of the Cu(II) loaded polymer is assured by energy‐dispersive X‐ray (EDX) elemental mapping, ICP and AAS spectroscopic analysis. The Cu(II) loaded material further employed as a heterogeneous catalyst for nitroarene reduction and reported as an excellent catalyst with improved performances over those reported using expensive and precious metals (like Au and Pd) on immobilized organic porous materials. The oxidation state of Cu in the catalytic cycle is corroborated with XPS analysis. The present study also emphasizes the role of π‐electron rich organic porous polymer as promoter of electronic stature of finely dispersed Cu sites accountable for the excellent catalytic activity towards nitroarene reduction.
A New Highly Efficient Method for the Catalyst‐Free Synthesis of Conjoined Twins 1,6‐Dioxaspiro Derivatives Through Double Reaction of Carbon Dioxide in One Reaction
Authors: Safaei Hamid Reza , Khastkhoda Tahereh , Shekouhy Mohsen 
Published: June 2018

AbstractA new highly efficient method for the catalyst‐free synthesis of germinal spiro compounds through a one‐pot three‐component condensation reaction of carbon dioxide, amines and dimethyl acetylenedicarboxylate at room temperature is described. In this methodology, both C=O bonds of CO2 are concurrently reacting in a one‐pot reaction. The structures of all obtained products were assigned with 1H and 13C NMR, MS, IR and elemental analysis.
Functionalized Pyrimidines from Alkynes and Nitriles: Application towards the Synthesis of Marine Natural Product Meridianin Analogs
Authors: Mohan Banyangala , Salfeena Chettiyan Thodi F. , Ashitha Kizhakkan T. , Krishnan Gopika V. , Jesmina Abdul Rasheed S. , Varghese Angela M. , Patil Siddappa A. , Kumar Bhaskaran Nair S. Dileep , Sasidhar Balappa S. 
Published: June 2018

AbstractFully substituted pyrimidine synthesis accomplished from alkynes and nitriles via BF3.Et2O mediated [2+2+2] cycloaddition. The substrate scope of the reaction was broad to include terminal alkynes to internal alkynes and aromatic nitriles to aliphatic nitriles furnished good to acceptable chemical yields. The marine alkaloid, meridianin analogs were synthesized successfully by utilizing this protocol. The pyrimidine analogues were also screened for their broad spectrum of antibacterial property against ten bacteria. Among the derivatives, 2,4‐dimethyl‐6‐p‐tolylpyrimidine (3b) has shown excellent inhibition potential against most of the tested organisms with a range of 9 to 21 mm zone of inhibition.
Mn(III)‐Based Oxidative Cyclization of Alkenes Using Tricarbonyl System
Authors: Huynh Thanh‐Truc , Yamakawa Hiroyasu , Nguyen Van‐Ha , Nishino Hiroshi 
Published: June 2018

AbstractThe Mn(III)‐based oxidation of 1,1‐disubstituted ethenes with 2‐(2‐aryl‐2‐oxoethyl)malonates, 2‐acetyl‐4‐aryl‐4‐oxobutanoates, and 3‐acetyl‐1‐arylpentane‐1,4‐diones was evaluated. The reaction using the malonates mainly gave the 2,3‐dihydro‐4H‐pyran‐4,4‐dicarboxylates along with γ‐lactones. A similar reaction using the acetyloxobutanoates and acetylpentanediones produced the 2,3,3a,6a‐tetrahydrofuro[2, 3‐b]furans and the corresponding dihydropyrans. The cyclization was strongly affected by the nucleophilicity of the carbonyl oxygen in the carbocation intermediate, and the kinetic and thermodynamic controls of the following reaction. The structure determination and the mechanisms are discussed.