bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nanofiltration membrane cross‐linked by m‐phenylenediamine for dye removal from textile wastewater
Authors: Gunawan Felicia Marcella , Mangindaan Dave , Khoiruddin K. , Wenten I Gede 
Published: October 2018

In this work, m‐phenylenediamine (MPD) is used to prepare cross‐linked polyetherimide (PEI)‐based nanofiltration (NF) membrane for treatment of dye containing wastewater. The effects of dope solution composition, cross‐linking time, and dye concentration on membrane performance are investigated. Results indicate that the rejection of dye is increased with the increase of acetone concentration in the dope solution, cross‐linking time, and dye concentration. Meanwhile, membrane flux showed the opposite trend. With the aid of SEM and FTIR analysis, the cross‐linking between MPD and PEI is confirmed. The cross‐linked membrane has thicker and dense selective layer compared to the unmodified membrane. The cross‐linked NF membrane (PEI: 15 wt%; acetone: 20 wt%; cross‐linking time: 10 minutes) showed good performance in filtration of synthetic dye wastewater (Reactive Red 120, 1500 ppm) with 98% dye rejection and 0.013 L m−2 hour−1 of flux at relatively low operating pressure (60 psi).
Identification of Duchenne/Becker muscular dystrophy mosaic carriers through a combined DNA/RNA analysis
Authors: Zampatti Stefania , Mela Julia , Peconi Cristina , Pagliaroli Giulia , Carboni Stefania , Barrano Giuseppe , Zito Ilaria , Cascella Raffaella , Marella Gianluca , Milano Filippo , Arcangeli Mauro , Caltagirone Carlo , Novelli Antonio , Giardina Emiliano 
Published: October 2018

AbstractObjectiveThe Duchenne/Becker muscular dystrophy (DMD) carrier screening includes the evaluation of mutations in DMD gene, and the most widely used analysis is the multiplex ligation‐dependent probe amplification (MLPA) for the DMD deletions/duplications detection. The high frequency of de novo mutations permits to estimate a risk up to 20% of mosaicisms for mothers of sporadic DMD children. The purpose of this study is to evaluate alternative analytical strategy for the detection of mosaics carrier women, in order to improve the recurrence risk estimation.MethodDifferent DNA and RNA analyses were conducted on samples from a woman that conceived a DMD fetus without previous family history of dystrophynopathy.ResultsStandard MLPA analysis failed to identify mosaicism, even if MLPA doses suggested it. Electrophoresis and direct sequencing conducted on RNA permitted to detect two different amplicons of cDNAs, demonstrating the presence of somatic mosaicism. Subsequent detection of a second affected fetus confirmed the mosaic status on the mother.ConclusionThe implementation of RNA analysis in diagnostic algorithm can increase the sensitivity of carrier test for mothers of sporadic affected patients, permitting detection of mosaic status. A revision of analytical guidelines is needed in order to improve the recurrence risk estimation and support prenatal genetic counseling.
Preparation and Application of La2O3 and CuO Nano Particles as Catalysts for Ammonium Perchlorate Thermal Decomposition
Authors: Pandas Hossein Momenizadeh , Fazli Mostafa 
Published: October 2018

AbstractNanoparticles (NPs) from lanthanum oxide (La2O3) and copper oxide (CuO) with spherical morphology were synthesized through precursor calcinations of copper and lanthanum carbonate and then using a bioactive shell membrane of eggshell. X‐ray diffraction (XRD) analysis and scanning electron microscopy (SEM) were used to evaluate particle size, chemical structure, purity and morphology of the synthesized La2O3 and CuO NPs. The XRD outcomes established the creation of the targeted compounds, SEM images obviously displayed morphology of the synthesized La2O3 and CuO as spherical NPs with average particle sizes of roughly 35 and 30 nm, correspondingly. The catalytic effects of these NPs on the thermal decomposition behavior of ammonium perchlorate (AP) were tested using differential scanning calorimetry (DSC) in coupling with thermo‐gravimetric analysis (TG). The results of these experiments showed that the addition of 5 % La2O3 nanoparticles has an attractive catalytic effect on the thermal decomposition of the AP. Moreover, AP thermal decomposition was facilitated by the addition of 5 % CuO NPs. A more accurate comparison was made between the catalytic effects of synthesized NPs via computing their thermal decomposition activation energies (E), ΔS#, ΔH# and ΔG# using diverse non‐isothermal approaches.
Particle Swarm Optimization of Kinetic Parameters for Thermal Cook‐Off Modelling
Authors: Seng Yeow Sing 
Published: October 2018

AbstractThe technique of Particle Swarm Optimization (PSO) was successfully applied to calibrate the kinetic parameters of the energetic material (EM) PBXN109. A total of nine parameters, was derived from a finite set of One Dimensional Time to Ignition (ODTX) experimental data by minimizing the difference between simulation and experimental ignition times. This difference was found to be 6.4 %, which is more than two times lower than those generated from the published kinetic parameters. This work demonstrates PSO as an effective optimization method for calibrating physical parameters of materials models used in EM modelling.
Combustion of Magnesium‐Sulfur Composite Particles Ignited by Different Stimuli
Authors: Monk Ian , Schoenitz Mirko , Dreizin Edward L. 
Published: October 2018

AbstractComposite Mg ⋅ S powders were prepared by mechanical milling. Magnesium powders coated with sulfur were prepared by soft milling using glass beads as milling media. Three‐dimensional composite powders, in which magnesium and sulfur were mixed on the nanoscale were prepared by milling using steel balls as milling media. Both composite powders were explored in two ignition experiments. In one case, monolayers of the prepared powders were exposed to electrostatic discharge (ESD). In the other case, powder particles were fed through a focused CO2 laser beam. In both experiments, emission traces produced by burning particles were captured using a filtered photomultiplier tube; the data were processed to recover respective combustion times. Combustion products were collected and examined using electron microscopy for the ESD‐ignition experiments. It was found that the burn times of the sulfur coated magnesium powders were shorter than those of three‐dimensional composites in both experiments. No effect of ignition method on burn times was observed for the sulfur‐coated powders. For three‐dimensional composite powder, burn times of ESD‐ignited particles were shorter than those for particles ignited by passing through the CO2 laser beam. Analysis of the captured combustion products suggests that magnesium and sulfur are readily separated upon heating for the coated powders, but not for the three‐dimensional composites. For the latter case, the reaction is dominated by MgS formation, while for the former case, it is primarily magnesium oxidation in air.
Antioxidant and spectral properties of chalcones and analogous aurones: Theoretical insights
Authors: Xue Yunsheng , Liu Yunping , Zhang Ling , Wang Han , Luo Qingquan , Chen Ran , Liu Yin , Li Ya 
Published: October 2018

AbstractDensity functional theory (DFT) and time‐dependent DFT (TD‐DFT) have been employed to elucidate the radical scavenging capacity and the UV–Vis spectral property of several chalcones and analogous aurones. Three main antioxidant mechanisms, hydrogen atom transfer (HAT), electron transfer followed by proton transfer (SET‐PT) and sequential proton loss electron transfer (SPLET) were investigated. The results indicate that all the studied compounds adopt a fully planar conformation in their neutral, radical, cationic as well as anionic forms. 2′‐OH plays important role in the stabilization of phenolic radicals due to the formation of intramolecular hydrogen bonds (IHBs). Introduction of electron‐donating substituent on B‐ring is helpful for improving the activity. For the considered compounds, HAT is proposed as the thermodynamically favored mechanism in gas phase and nonpolar environment, while SPLET is preferred in polar media. The results confirmed the crucial role of hydroxyl group on A‐ring, especially on position 5′/5, in terms of the radical scavenging ability. The absorption spectra of title compounds were successfully simulated and the lowest energy transitions predominantly correspond to the π‐π* transitions from HOMO to LUMO with charge transfer (CT) character.
Concise Reviews: Stem Cells and Kidney Regeneration: An Update
Authors: Marcheque Julia , Bussolati Benedetta , Csete Marie , Perin Laura 
Published: October 2018

Abstract
Significant progress has been made to advance stem cell products as potential therapies for kidney diseases: various kinds of stem cells can restore renal function in preclinical models of acute and chronic kidney injury. Nonetheless this literature contains contradictory results, and for this reason, we focus this review on reasons for apparent discrepancies in the literature, because they contribute to difficulty in translating renal regenerative therapies. Differences in methodologies used to derive and culture stem cells, even those from the same source, in addition to the lack of standardized renal disease animal models (both acute and chronic), are important considerations underlying contradictory results in the literature. We propose that harmonized rigorous protocols for characterization, handling, and delivery of stem cells in vivo could significantly advance the field, and present details of some suggested approaches to foster translation in the field of renal regeneration. Our goal is to encourage coordination of methodologies (standardization) and long-lasting collaborations to improve protocols and models to lead to reproducible, interpretable, high-quality preclinical data. This approach will certainly increase our chance to 1 day offer stem cell therapeutic options for patients with all-too-common renal diseases. Stem Cells Translational Medicine 2019;8:82–92
Model averaging for robust extrapolation in evidence synthesis
Authors: Röver Christian , Wandel Simon , Friede Tim 
Published: October 2018

Extrapolation from a source to a target, eg, from adults to children, is a promising approach to utilize external information when data are sparse. In the context of meta‐analyses, one is commonly faced with a small number of studies, whereas potentially relevant additional information may also be available. Here, we describe a simple extrapolation strategy using heavy‐tailed mixture priors for effect estimation in meta‐analysis, which effectively results in a model‐averaging technique. The described method is robust in the sense that a potential prior‐data conflict, ie, a discrepancy between source and target data, is explicitly anticipated. The aim of this paper is to develop a solution for this particular application to showcase the ease of implementation by providingR code, and to demonstrate the robustness of the general approach in simulations.
In Situ Formation of a 3D Amorphous Cobalt‐ Borate Nanoarray: An Efficient Non‐Noble Metal Catalytic Electrode for Non‐Enzyme Glucose Detection
Authors: Deng Wenqing , Dai Rui , You Chao , Hu Pingyue , Sun Xuping , Xiong Xiaoli , Huang Ke , Huo Feng 
Published: October 2018

AbstractIt is highly desirable to design enzyme‐free nanoarray architecture as an efficient three‐dimensional (3D) catalyst electrode for sensitive and selective detection of glucose. In this communication, we report that in situ electrochemical development of an amorphous cobalt‐borate nanoarray supported on carbon cloth (Co–Bi /CC) as a durable and efficient 3D nanoarray electrocatalyst for glucose detection. As a glucose sensor, Co−Bi/CC electrode shows a fast amperometric response toward glucose, a detection limit of 0.042 μM (S/N=3), a response sensitivity of 4191.7 μA mM−1 cm−2. Importantly, it also demonstrates favourable reproducibility and long‐term stability.
Effect of pH of Precursor on Up/Downconversion and Cathodoluminescence of Gd2O3:Ho3+/Yb3+ Phosphor and Magneto‐Optic Studies
Authors: Kumar Abhishek , Couto Maria H. M. , Tiwari Surya P. , Kumar Kaushal , Esteves da Silva Joaquim C. G. 
Published: October 2018

AbstractThe effect of pH of precursor solution has studied on structural and up/downconversion emission properties of Ho3+/Yb3+ doped Gd2O3 host synthesized through hydrothermal route. Best sample morphology (rod‐shaped) is found corresponding to the pH value of pH‐9.1 of the precursor solution. Due to the low phonon frequency of Gd2O3 host, intense green upconversion emission around 539, 550 nm wavelength is observed from the sample on 980 nm diode laser excitation. In down conversion emission mode, bands around 539, 550 nm and 653 nm are found on 449 nm arc lamp excitation. The prepared samples were further studied for cathodoluminescence and the effect of magnetic field on the upconversion emission. The sample has also shown optical bi‐stability in upconversion emission when the magnetic field was increased from zero to 1.05x104 Oe and then decreased to zero.
One Ni(II) Polymer with Fluorescent Response Based on Mixed Ligands
Authors: Yin Xiu‐Ju , Zhu Long‐Guan 
Published: October 2018

AbstractOne new nickel polymer [Ni(L)2⋅(3‐Sb)]n (1) (L=2‐pyrimidinecarboximidamide; 3‐Sb=3‐sulfo‐benzoic acid) has been synthesized and it is characterized by single‐crystal X‐ray diffraction, FTIR and elemental analysis. The results show that polymer 1 belongs to the monoclinic system, P21/n space group, with a=11.3572(8), b=13.1745(8), c=13.2345(9) Å, β=98.887(6)°, V=1956.4(2) Å3, Mr=535.13. TGA shows that polymer 1 began to decompose at 230 C, which indicates 1 have good thermal stability. The fluorescence analysis of 1 in the solid state at room temperature shows that this new Ni(II) polymer material has good fluorescence response.
Development of a Water‐Dispersible SBA‐15‐Benzothiazole‐Derived Fluorescence Nanosensor by Physisorption and Its Use in Organic‐Solvent‐Free Detection of Perborate and Hydrazine
Authors: Gawas Ram U. , Anand Shivesh , Ghosh Barun K. , Shivbhagwan Princee , Choudhary Kushav , Ghosh Narendra Nath , Banerjee Mainak , Chatterjee Amrita 
Published: October 2018

AbstractWe have synthesized a water dispersible SBA‐15 based sensing material (nanosensor 1) for the detection of perborate ions and hydrazine in water. The nanosensor was prepared by simple physisorption of chemosensing unit 2‐(benzo[d]thiazol‐2‐yl)phenyl acetate (2) onto PEG‐stabilized SBA‐15. The probe molecule undergoes spontaneous cleavage of acetate group in the presence of both perborate ions and hydrazine to produce corresponding phenol (3), which results in greenish blue fluorescence by excited state intra‐molecular proton transfer (ESIPT) mechanism. The limit of detection (LOD) for both analytes was observed in ppb level; 49.9 ppb for perborate ions and 8.0 ppb for hydrazine. Simple synthesis, effortless modification, high water dispersibility make this nanosensor very efficient for perborate ions and hydrazine. Finally, this is a demonstration of the physisorption strategy in building useful sensing materials which can be applied to any analyte based on the choice of a suitable chemosenors.
Efficient Ternary Organic Solar Cells with Two Compatible Non‐Fullerene Materials as One Alloyed Acceptor
Authors: An Qiaoshi , Zhang Jian , Gao Wei , Qi Feng , Zhang Miao , Ma Xiaoling , Yang Chuluo , Huo Lijun , Zhang Fujun 
Published: October 2018

AbstractEfficient ternary organic solar cells (OSCs) are fabricated by employing a polymer PBT1‐C as the donor and two non‐fullerene materials, MeIC and MeIC2, as one alloyed acceptor. The optimized ternary OSCs with 30 wt% MeIC2 in acceptors achieve a power conversion efficiency (PCE) of 12.55%, which is much higher than that of 11.47% for MeIC‐based binary OSCs and 11.41% for MeIC2‐based binary OSCs. The >9.4% improvement in PCE is mainly attributed to the optimized photon harvesting and morphology of ternary active layers, resulting in the simultaneously improved short‐circuit current and fill factor. Furthermore, good compatibility and similar lowest unoccupied molecular orbital energy levels of MeIC and MeIC2 are beneficial to form one alloyed acceptor for efficient electron transport in the ternary active layers. This work may provide new insight when selecting the third component for preparing efficient ternary OSCs.
Fabrication of a homogeneous large‐volume polymethacrylate monolith: A thermal mixing approach
Authors: Chan Yi Wei , Adam Siti Nurul N. , Obeng Eugene M. , Ongkudon Clarence M. 
Published: October 2018

AbstractTo date, the reported works relating to the utilization of monolith in multi‐omics applications are mostly limited to analytical scale due to limited progress in the development of large‐scale monolith. In the case of polymethacrylate monolith, the up‐scaling progress has been hampered by issues pertaining to excessive internal heat build‐up as a function of poor heat transfer which leads to defects in pore homogeneity and often results in cracking of the adsorbent. Herein, this article presents the proof of concept of a thermal mixing method to address the impediments of heat build‐up in monolith up‐scaling. In this method, the upsurge of heat was alleviated by modulating the heat input into and out of the monolith mixture throughout the course of bulk free radical polymerization. The resulting 150 mL polymethacrylate monolith showed about 56.3% reduction in peak thermal build‐up and featured homogeneous pores throughout the adsorbent. This research has put forward an interesting concept of minimizing the intensity of thermal build‐up. The overall outcome generated from this research is encouraging for heat‐based monolith upscaling.
Real‐time hybrid aeroelastic simulation of wind turbines with various types of full‐scale tuned liquid dampers
Authors: Zhang Zili , Basu Biswajit , Nielsen Søren R.K. 
Published: October 2018

AbstractThe present paper presents the real‐time hybrid simulation (RTHS) technique for multimegawatt wind turbine (WT) with various types of full‐scale tuned liquid dampers (TLDs). As an evolvement of the pseudodynamic testing technique, the RTHS is executed in real time, thus allowing accurate investigation of the interaction between the aeroelastic WT system and the rate‐dependent nonlinear TLD device. As the numerical substructure, the WT is simulated in the computer using a 13‐degree‐of‐freedom (13‐DOF) aeroelastic model. As the physical substructure, the full‐scale TLDs are manufactured and physically tested. They are synchronized with each other by real‐time controllers. Taking advantage of RTHS technique, 2‐ and 3‐MW WTs have both been simulated under various turbulent wind conditions. TLDs with different configurations have been extensively investigated, eg, various tuning ratios by varying the water level, TLD without and with damping screens (various mesh sizes of the screen considered), and TLD with flat and sloped bottoms. It is shown that a well‐designed TLD is very effective in damping lateral tower vibrations of WTs. Furthermore, RTHS results and results from a proposed theoretical model are compared. This study gives comprehensive guidelines for employing various types of TLDs in large WTs and indicates huge potentials of applying RTHS technique in the area of wind energy.
Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci
Authors: Shah Rupal L. , Guggenheim Jeremy A. ,   UK Biobank Eye and Vision Consortium
Published: October 2018

AbstractPrevious studies have suggested that naturally occurring genetic variation contributes to the risk of astigmatism. The purpose of this investigation was to identify genetic markers associated with corneal and refractive astigmatism in a large-scale European ancestry cohort (UK Biobank) who underwent keratometry and autorefraction at an assessment centre. Genome-wide association studies for corneal and refractive astigmatism were performed in individuals of European ancestry (N = 86,335 and 88,005 respectively), with the mean corneal astigmatism or refractive astigmatism in fellow eyes analysed as a quantitative trait (dependent variable). Genetic correlation between the two traits was calculated using LD Score regression. Gene-based and gene-set tests were carried out using MAGMA. Single marker-based association tests for corneal astigmatism identified four genome-wide significant loci (P < 5 × 10−8) near the genes ZC3H11B (1q41), LINC00340 (6p22.3), HERC2/OCA2 (15q13.1) and NPLOC4/TSPAN10 (17q25.3). Three of these loci also demonstrated genome-wide significant association with refractive astigmatism: LINC00340, HERC2/OCA2 and NPLOC4/TSPAN10. The genetic correlation between corneal and refractive astigmatism was 0.85 (standard error = 0.068, P = 1.37 × 10−35). Here, we have undertaken the largest genome-wide association studies for corneal and refractive astigmatism to date and identified four novel loci for corneal astigmatism, two of which were also novel loci for refractive astigmatism. These loci have previously demonstrated association with axial length (ZC3H11B), myopia (NPLOC4), spherical equivalent refractive error (LINC00340) and eye colour (HERC2). The shared role of these novel candidate genes for astigmatism lends further support to the shared genetic susceptibility of myopia and astigmatism.
Appropriate use criteria for lumbar puncture and cerebrospinal fluid testing in the diagnosis of Alzheimer's disease
Authors: Shaw Leslie M. , Arias Jalayne , Blennow Kaj , Galasko Douglas , Molinuevo Jose Luis , Salloway Stephen , Schindler Suzanne , Carrillo Maria C. , Hendrix James A. , Ross April , Illes Judit , Ramus Courtney , Fifer Sheila 
Published: October 2018

AbstractIntroductionThe Alzheimer's Association convened a multidisciplinary workgroup to develop appropriate use criteria to guide the safe and optimal use of the lumbar puncture procedure and cerebrospinal fluid (CSF) testing for Alzheimer's disease pathology detection in the diagnostic process.MethodsThe workgroup, experienced in the ethical use of lumbar puncture and CSF analysis, developed key research questions to guide the systematic review of the evidence and developed clinical indications commonly encountered in clinical practice based on key patient groups in whom the use of lumbar puncture and CSF may be considered as part of the diagnostic process. Based on their expertise and interpretation of the evidence from systematic review, members rated each indication as appropriate or inappropriate.ResultsThe workgroup finalized 14 indications, rating 6 appropriate and 8 inappropriate.DiscussionIn anticipation of the emergence of more reliable CSF analysis platforms, the manuscript offers important guidance to health‐care practitioners and suggestions for implementation and future research.