bluuebunny/crossref_metadata_2025_split huggingface dataset:
D2 autoreceptor switches CB2 receptor effects on [3H]‐dopamine release in the striatum
Authors: López‐Ramírez Gabriel , Sánchez‐Zavaleta Rodolfo , Ávalos‐Fuentes Arturo , José Sierra Juan , Paz‐Bermúdez Francisco , Leyva‐Gómez Gerardo , Segovia Vila José , Cortés Hernán , Florán Benjamín 
Published: October 2019

AbstractCB2 receptors (CB2R) are expressed in midbrain neurons. To evidence the control of dopamine release in dorsal striatum by CB2R, we performed experiments of [3H]‐dopamine release in dorsal striatal slices. We found a paradoxical increase in K+‐induced [3H]‐dopamine release by CB2R activation with GW 833972A and JWH 133 two selective agonist. To understand the mechanism involved, we tested for a role of the D2 autoreceptor in this effect; because in pallidal structures, the inhibitory effect of CB1 receptors (CB1R) on GABA release is switched to a stimulatory effect by D2 receptors (D2R). We found that the blockade of D2 autoreceptors with sulpiride prevented the stimulatory effect of CB2R activation; in fact, under this condition, CB2R decreased dopamine release, indicating the role of the D2 autoreceptor in the paradoxical increase. We also found that the effect occurs in nigrostriatal terminals, since lesions with 6‐OH dopamine in the middle forebrain bundle prevented CB2R effects on release. In addition, D2–CB2R interaction promoted cAMP accumulation, and the increase in [3H]‐dopamine release was prevented by PKA blockade. D2–CB2R coprecipitation and proximity ligation assay studies indicated a close interaction of receptors that could participate in the observed effects. Finally, intrastriatal injection of CB2R agonist induced contralateral turning in amphetamine‐treated rats, which was prevented by sulpiride, indicating the role of the interaction in motor behavior. Thus, these data indicate that the D2 autoreceptor switches, from inhibitory to stimulatory, the CB2R effects on dopamine release, involving the cAMP → PKA pathway in nigrostriatal terminals.
Neural mechanisms of decision‐making in aging
Authors: Lighthall Nichole R. 
Published: October 2019

AbstractThe present review synthesizes findings on decision neuroscience and aging by focusing on decision processes that have been extensively studied in neuroeconomics and critically assessing the driving mechanisms of age‐related change. The paper first highlights age‐related changes to key brain structures that have been implicated in decision‐making, then, reviews specific decision components and discusses investigations of age‐related changes to their neural mechanisms. The review also weighs evidence for organic brain aging versus age‐related changes to social and psychological factors in mediating age effects. Reviewed findings are discussed in the context of theories and frameworks that have been used to explain trajectories of change in decision‐making across adulthood.This article is categorized under:

Psychology > Development and Aging
Psychology > Reasoning and Decision‐Making
Neuroscience > Cognition
Genetic Diversity of Potato Cultivars for Nitrogen Use Efficiency Under Contrasting Nitrogen Regimes
Authors: Getahun Baye Berihun , Kassie Molla Mekonen , Visser Richard G. F. , van der Linden C. Gerard 
Published: October 2019

AbstractDeveloping cultivars that use nitrogen more efficiently is a sustainable strategy for reducing nitrogen use in crop production. To assess the genetic diversity for nitrogen use efficiency (NUE) and related traits in potato, a total of 97 (88 for the Western-European market and 9 Ethiopian) cultivars were evaluated at two nitrogen levels (40 kg/ha and 120 kg/ha) for 24 quantitative traits in Debre-Tabor and Injibara (Ethiopia) in the 2013 main rainy season (June to September). Highly significant variation was found among genotypes for almost all measured traits. Plant height, NUE, tuber yield, and yield-related traits and model parameters for canopy development (maximum canopy covers area under the canopy curve) were significantly affected by N levels across locations. Dutch cultivars had more rapid initial canopy development and matured earlier than the Ethiopian cultivars at both N levels and locations. A hierarchical cluster analysis grouped the cultivars in 9 and 11 genetically distinct classes at low and high N, respectively. The genetic component accounted for a large portion of the phenotypic variation for plant height, tuber number per plant, average tuber weight, and NUE under both N regimes, as indicated by a high heritability. Strong phenotypic correlations were observed between NUE and tuber number per plant, days to maturity, tuber dry matter %, maximum canopy cover, and area under the canopy curve under both low and high N conditions. The result is indicative to set the best parental line selection criteria for crossing purpose and utilize the cultivars for further potato NUE breeding programmes.
Total pleural coverage followed by lung transplantation in patient with lymphangioleiomyomatosis
Authors: Kim Do Hyung , Ahn Hyo Yeong , Son Bong Soo , Son Joohyung 
Published: October 2019

Abstract
Tuberous sclerosis complex lymphangioleiomyomatosis (TSC-LAM) is a rare disease, which may develop an intractable pneumothorax. Chemical or mechanical pleurodesis is a general management to prevent recurrence of pneumothorax, rendering it difficult to later dissect the pleura and control intraoperative bleeding. Since total pleural coverage (TPC) alternative to pleurodesis has been firstly reported by Kurihara et al. (Jpn J Thorac Cardiovasc Surg 54:274, 2006), TPC was performed in case of a 46-year-old female with a secondary spontaneous pneumothorax caused by TSC-LAM and followed by lung transplantation. Final pathological report showed the reinforced visceral pleura in the absence of dense adhesions.
Detection performance and inversion processing of logging-while-drilling extra-deep azimuthal resistivity measurements
Authors: Wang Lei , Deng Shao-Gui , Zhang Pan , Cao Ying-Chang , Fan Yi-Ren , Yuan Xi-Yong 
Published: October 2019

AbstractWe present systematic investigations on the physics, detection performance and inversion of logging-while-drilling extra-deep azimuthal resistivity measurements (EDARM). First, the definitions of EDRAM measurements are discussed, followed by the derivation of the attenuation and phase-shift geometrical factors to illustrate the relative contributions of formation units to the observed signals. Then, a new definition of detection depth, which considers the uncertainty of inversion results caused by the data noise, is proposed to quantify the detection capability of EDARM. Finally, the Bayesian theory associated with Markov chain Monte Carlo sampling is introduced for fast processing of EDARM data. Numerical results show that EDARM is capable of detecting the azimuth and distance of remote bed boundaries, and the detection capability increases with increasing spacing and resistivity contrast. The EDARM tool can accommodate a large range of formation resistivity and is able to provide the resistivity anisotropy at arbitrary relative dipping angles. In addition, multiple bed boundaries and reservoir images near the borehole are readily obtained by using the Bayesian inversion.
Geophysical characterization and hydraulic properties of unconsolidated floodplain aquifer system in Wamako area, Sokoto State, north-western Nigeria
Authors: Akinbiyi O. A. , Oladunjoye M. A. , Sanuade O. A. , Oyedeji O. 
Published: October 2019

Abstract
The subsurface internal geometry of Rima River floodplain located in north-western area of Nigeria was investigated using 2D resistivity imaging, vertical electrical sounding (VES) and laboratory analyses. Four profiles were acquired using Wenner array. The apparent resistivity computed was used to produce 2D electrical resistivity pseudosections using RES2DINV software. A total of nine VESs were acquired along the four profiles in the study area with AB/2 of 1 to 100 m. Quantitative interpretation of VES curves was done by partial curve matching and computer-assisted 1D forward modelling with the WinResist version 1.0 software. Five pits were dug along the profiles to confirm the interpreted results from the geophysical surveys. Soil samples were collected from the pits at various depths, and hydraulic conductivity (K) was estimated in the laboratory using the constant head permeability test following standard procedure. Interpretations of electrical resistivity technique show three to four subsurface layers including topsoil, sandy material and clay/saturated clayey materials. The sandy material is believed to be saturated with water with appreciable amount of porosity and permeability. This layer was further confirmed by pitting around the study area. From the laboratory and empirical estimation of K, it was discovered that the K value ranges from 10−2 to 10−6 m/s, which shows that the sample is clean sand which is moderately to highly permeable. The grain size analysis revealed from the cumulative plot that the sample falls predominantly within medium-sized sand, which makes the study area a good aquifer system.
Zirconia nanoparticle-modified graphitic carbon nitride nanosheets for effective photocatalytic degradation of 4-nitrophenol in water
Authors: Zarei Mohanna , Bahrami Jamil , Zarei Mohammad 
Published: October 2019

Abstract
Zirconia (ZrO2)-modified graphitic carbon nitride (g-C3N4) nanocomposite was used for effective photodegradation of 4-nitrophenol (4-NP) in water. The ZrO2 nanoparticles, g-C3N4 nanosheets, and ZrO2/g-C3N4 nanocomposite were well characterized by including N2 adsorption, X-ray diffraction, Fourier transform infrared spectroscopy, field emission scanning electron microscopy, UV–Vis diffuse reflectance spectroscopy, photoelectrochemical measurements, and photoluminescence spectroscopy methods. ZrO2/g-C3N4 nanocomposites were formed at room temperature using sonication and used for effective for photodegradation of 4-NP under irradiation with visible light. The nanocomposite samples resulted in a significant increase in photocatalytic activity compared with single-component samples of g-C3N4. In particular, the ZrO2/g-C3N4 nanocomposite exhibited the significant increase in the photocatalytic activity. The ZrO2/g-C3N4 nanocomposite showed an excellent catalytic activity toward the reduction of 4-NP in aqueous medium. Further, ZrO2/g-C3N4 nanocomposite can be reused several times for photocatalytic degradation as well as for 4-NP adsorption.
Electrical behavior of graphene under temperature effect and survey of I–T curve
Authors: Haditale M. , Dariani R. S. , Ghasemian Lemraski E. 
Published: October 2019

AbstractGraphene flakes were made from electrochemical exfoliation. To study graphene planes, different volumes of graphene solutions (1, 2, 4, and 7 ml) were sprayed on glass lamellae to get different graphene planes.I–Vcurve of all samples shows ohmic behavior with resistance in the order of kΩ which increases the slope of theI–Vcurve with increasing graphene planes (spray volume). The effect of temperature on all samples shows a clear jump inI–Tcurves. It is found that up to 150 °C current is almost constant, but after that current increases highly in the range of 1.8–10 times and resistance reduces sharply. Also, samples with lower graphene planes affected highly with temperature effect.
Major cardiovascular disease (CVD) risk factors in midlife and extreme longevity
Authors: Urtamo Annele , Jyväkorpi Satu K. , Kautiainen Hannu , Pitkälä Kaisu H. , Strandberg Timo E. 
Published: October 2019

Abstract

Background
The studies on the association of various midlife risk factors with reaching 90 years or more are scarce. We studied this association in a socioeconomically homogenous cohort of businessmen.

Methods
The study consists of men (n = 970) from the Helsinki Businessmen Study cohort (born 1919–1928). Five major cardiovascular disease (CVD) risk factors (smoking, BMI, blood pressure, serum lipids, fasting glucose), consumption of alcohol and coffee, self-rated health and self-rated fitness, were assessed in 1974, at an average age of 50 years. The number of major risk factors was tested as a risk burden. The Charlson Comorbidity Index and the RAND-36 (SF-36) Physical and Mental health summary scores were calculated from surveys in year 2000, at age of 73 years. Mortality dates were retrieved through 31 March 2018 from the Population Information System of Finland.

Results
244 men survived to the age of 90 representing 25.2% of the study cohort. The survivors had less risk factor burden in midlife, and less morbidity and higher physical health summary score in 2000. Of those with five major risk factors only 7% survived up to 90 years, whereas 51% of those without any risk factors reached that age. Single risk factors reducing odds of reaching 90 years were smoking (odds ratio [OR] 0.48, 95% confidence interval [CI] 0.34–0.67), glucose (0.66, 0.49–0.88), BMI (0.63, 0.46–0.86), and cholesterol (0.71, 0.53–0.96).

Conclusion
Lack of five major CVD risk factors in midlife strongly increased odds of reaching 90 years of age and also predicted factors related to successful ageing in late life.
Question of ethnic group formulation in the Chinese census
Authors: Zhou Yun 
Published: October 2019

Abstract
In conjunction with official government information and existing research literature, this article discusses ethnic group formulation in the censuses of China since 1953. Followed by an examination of concept of “ethnicity”, the research explores the purpose of the question included in the census, ways to answer the census question, and changes in number of official ethnic groups finalized until 1980s in China. To make a good study on ethnicity by census statistics, we have to understand the system of census taking on ethnicity in different countries. As a country with different minority groups, China is undergoing a social transformation and improving its census-taking. Ethnicity-related information collected in the census will play a more important role in the development of Chinese society.
Recharacterizing Corruption to Encompass Illicit Financial Flows
Authors: Gathii James Thuo 
Published: October 2019

Anticorruption treaties generally define corruption as the abuse of entrusted power for private gain. As such, global anticorruption efforts primarily target transactions involving the bribery of governmental officials. The definition excludes transactions in which multinational corporations deprive developing states of revenue by failing to pay taxes and other monies due. Yet such transactions are equally injurious to the development agenda of poor states. This essay argues that corruption should be redefined to encompass illicit financial flows, a term used by a growing network of tax and economic justice groups to refer to money that is “illegally earned, transferred or used.” Transactions such as trade misinvoicing, base-erosion, and abusive transfer pricing to illegally earn additional income undermine the ability of poor states to raise revenue for development. Expanding the definition of corruption would create a more realistic picture of the role of corporate actors and their involvement in corrupt and illicit dealings. It would also bring equivalency to the treatment of corporate actors and public officials. By focusing on illicit dealings involving corporate actors, this essay challenges the partial definition of corruption adopted in the heyday of the Washington Consensus, when skepticism about the role of the state, rather than of private actors, prevailed.
Coeval brittle and ductile deformation beneath the late Wisconsinan Puget Lobe, Washington State, USA
Authors: Knight Jasper 
Published: October 2019

AbstractLate Wisconsinan glacial sediments, exposed on Whidbey Island and Camano Island, Puget Sound (Washington State, USA), were deposited in a proglacial shallow marine/outwash environment during northward retreat of the Puget Lobe of the Cordilleran ice sheet. Sediments mainly comprise massive and cross-bedded sand and gravels, and rhythmically-bedded clay and silt/fine sand couplets, interbedded with diamictons that were deposited by a range of mass flows of different viscosities. Although sediment stratigraphy and ice advance–retreat patterns are well established for the Puget Lobe, brittle and ductile deformation structures within, and separating, these sediment units are less well understood. These structures record the nature of ice–bed interactions taking place in subglacial and proglacial environments. This study examines evidence for these processes and environments. Key deformation structures identified include open to overturned folds, normal and reverse faults, clastic dikes and hydrofractures and passive-loading structures. Evidence for coeval development of ductile and brittle deformation structures shows the close relationship between porewater changes, sediment rheology and sediment system responses to changes in strain caused by ice–bed interactions.
Towards global business engagement with development goals? Multilateral institutions and the SDGs in a changing global capitalism
Authors: Bull Benedicte , Miklian Jason 
Published: October 2019

AbstractOver the last decades, encouragement of business engagement with environmental and socio-economic development has gained prominence due to the perceived weakening of states and multilateral institutions against the forces of global capitalism. Different ways of encouraging changes in business behavior have been promoted, such as the formation of public/private partnerships, corporate social responsibility initiatives, and other forms of non-binding organizational arrangements. However, there is no real consensus on the desired role of business in development, what the best policies for global development are, or what “development” itself is and should be defined as. Indeed, precisely as a formal consensus has been reached on the broad agenda of the United Nations Sustainable Development Goals, a narrower agenda focusing on industrialization, modernization, and economic growth is promoted by new actors, many originating in the Global South. This special issue asks how the emergence of new actors and the adaptation by global institutions affect the ways in which business engages with development. This introductory article positions the issue's contributions into three discussions: exploring issues of global coherence and division on key debates; understanding how new actors are reshaping the public-private divide; and assessing how disconnects within discourse on business and development can amplify negative societal consequences in fragile settings of weak governance.
Why do I contribute to organizational learning when I am ostracized? A moderated mediation analysis
Authors: Imran Muhammad Kashif , Iqbal Jawad , Fatima Tehreem , Iqbal Syed Muhammad Javed , Jamal Warda Najeeb , Nawaz Muhammad Shahid 
Published: October 2019

AbstractDrawing on social exchange and emotional regulation perspectives, this study investigates the role of emotional suppression in reducing the detrimental effects of workplace ostracism on organizational learning. Based on the responses of 162 participants from the financial industry, and with the application of moderated mediation analysis, the findings demonstrate that workplace ostracism is mediated by employee silence, which has a negative effect on organizational learning. Interestingly, however, the results exhibit that emotional suppression operates as a buffer between workplace ostracism, employee silence and organizational learning, which leads to the achievement of organizational learning motives. Therefore, the silent employees, who experience workplace ostracism, may still be contributing toward organizational learning, if they are proficient in suppressing their emotions. Given that, the study implies that emotional suppression is fundamentally important to reduce the injurious outcomes of workplace ostracism, in the contemporary organizational settings, particularly with regard to organizational learning.
Trade and redistribution: trade politics and the origins of progressive taxation
Authors: Barnes Lucy 
Published: October 2019

AbstractWhat explains variation in tax progressivity before World War I? I argue that trade politics shaped the emergence of progressive taxation. If labor could provide a useful ally, trade policy coalitions meant compromise on redistributive demands: progressive taxes, especially where inequality was lower. In time-series cross-sectional analysis, I find that trade interest proximity between labor and elites was associated with more progressive taxation in ten European countries between 1870 and 1913 under conditions of low inequality. The coalition and compromise mechanism is evident in sub-national evidence from Britain. Where constituency interests favored free trade, Liberal–Labour electoral alliance was more likely in 1906, and the local MP was more likely to support the 1909 “People's Budget” for progressive taxation.
Voluntary medical male circumcision and HIV in Zambia: expectations and observations
Authors: Garenne Michel , Matthews Alan 
Published: October 2019

AbstractThe study analysed the HIV/AIDS situation in Zambia six years after the onset of mass campaigns of Voluntary Medical Male Circumcision (VMMC). The analysis was based on data from Demographic and Health Surveys (DHS) conducted in 2001, 2007 and 2013. Results show that HIV prevalence among men aged 15–29 (the target group for VMMC) did not decrease over the period, despite a decline in HIV prevalence among women of the same age group (most of their partners). Correlations between male circumcision and HIV prevalence were positive for a variety of socioeconomic groups (urban residence, province of residence, level of education, ethnicity). In a multivariate analysis, based on the 2013 DHS survey, circumcised men were found to have the same level of infection as uncircumcised men, after controlling for age, sexual behaviour and socioeconomic status. Lastly, circumcised men tended to have somewhat riskier sexual behaviour than uncircumcised men. This study, based on large representative samples of the Zambian population, questions the current strategy of mass circumcision campaigns in southern and eastern Africa.
Blunt neck trauma at a level I trauma centre: six-year retrospective case note review
Authors: Zakaria B A , Muzaffar J , Orr L E , Coulson C J , Sharma N 
Published: October 2019

AbstractBackgroundBlunt neck trauma can cause serious morbidity and mortality rates of up to 40 per cent, but there is a paucity of literature on the topic.MethodA retrospective case note review was performed for all blunt neck trauma cases managed at the Queen Elizabeth Hospital Birmingham between 1st January 2011 and 31st December 2017.ResultsSeventeen cases were managed, with no mortality and limited morbidity. Most patients were male (70.6 per cent) and road traffic accidents were the most common cause of injury (41.2 per cent). The median age of patients was 40.6 years (range, 21.5–70.3 years). Multidetector computed tomography angiography of the neck was performed in 9 patients (52.9 per cent) with ‘hot’ reports made by on-duty radiology staff matching consultant reports in all but 1 case. Six patients underwent operative exploration yielding a negative exploration rate of 33.3 per cent. Imaging reports matched operative findings in 3 cases (60 per cent).ConclusionBlunt neck trauma is uncommon but usually presents in polytrauma. Imaging has inaccuracies when compared with operative findings, regardless of radiological experience.