bluuebunny/crossref_metadata_2025_split huggingface dataset:
Headache, tinnitus and hearing loss in the international Cohort Study of Mobile Phone Use and Health (COSMOS) in Sweden and Finland
Authors: Auvinen Anssi , Feychting Maria , Ahlbom Anders , Hillert Lena , Elliott Paul , Schüz Joachim , Kromhout Hans , Toledano Mireille B , Johansen Christoffer , Poulsen Aslak Harbo , Vermeulen Roel , Heinävaara Sirpa , Kojo Katja , Tettamanti Giorgio ,   COSMOS Study Group, Danker-Hopfe Heidi , Inskip Hazel , Röösli Martin 
Published: June 2019

Abstract

Background
Mobile phone use and exposure to radiofrequency electromagnetic fields (RF-EMF) from it have been associated with symptoms in some studies, but the studies have shortcomings and their findings are inconsistent. We conducted a prospective cohort study to assess the association between amount of mobile phone use at baseline and frequency of headache, tinnitus or hearing loss at 4-year follow-up.

Methods
The participants had mobile phone subscriptions with major mobile phone network operators in Sweden (n = 21 049) and Finland (n = 3120), gave consent for obtaining their mobile phone call data from operator records at baseline, and filled in both baseline and follow-up questionnaires on symptoms, potential confounders and further characteristics of their mobile phone use.

Results
The participants with the highest decile of recorded call-time (average call-time >276 min per week) at baseline showed a weak, suggestive increased frequency of weekly headaches at 4-year follow-up (adjusted odds ratio 1.13, 95% confidence interval 0.95–1.34). There was no obvious gradient of weekly headache with increasing call-time (P trend 0.06). The association of headache with call-time was stronger for the Universal Mobile Telecommunications System (UMTS) network than older Global System for Mobile Telecommunications (GSM) technology, despite the latter involving higher exposure to RF-EMF. Tinnitus and hearing loss showed no association with call-time.

Conclusions
People using mobile phones most extensively for making or receiving calls at baseline reported weekly headaches slightly more frequently at follow-up than other users, but this finding largely disappeared after adjustment for confounders and was not related to call-time in GSM with higher RF-EMF exposure. Tinnitus and hearing loss were not associated with amount of call-time.
Self-similark-Graph C*-Algebras
Authors: Li Hui , Yang Dilian 
Published: June 2019

AbstractIn this paper, we introduce a notion of a self-similar action of a group $G$ on a $k$-graph $\Lambda $ and associate it a universal C$^\ast $-algebra ${{\mathcal{O}}}_{G,\Lambda }$. We prove that ${{\mathcal{O}}}_{G,\Lambda }$ can be realized as the Cuntz–Pimsner algebra of a product system. If $G$ is amenable and the action is pseudo free, then ${{\mathcal{O}}}_{G,\Lambda }$ is shown to be isomorphic to a “path-like” groupoid C$^\ast $-algebra. This facilitates studying the properties of ${{\mathcal{O}}}_{G,\Lambda }$. We show that ${{\mathcal{O}}}_{G,\Lambda }$ is always nuclear and satisfies the universal coefficient theorem; we characterize the simplicity of ${{\mathcal{O}}}_{G,\Lambda }$ in terms of the underlying action, and we prove that, whenever ${{\mathcal{O}}}_{G,\Lambda }$ is simple, there is a dichotomy: it is either stably finite or purely infinite, depending on whether $\Lambda $ has nonzero graph traces or not. Our main results generalize the recent work of Exel and Pardo on self-similar graphs.
Integrated community-based intervention for urinary schistosomiasis and soil-transmitted helminthiasis in children from Caxito, Angola
Authors: Lemos Manuel , Fançony Cláudia , Moura Sofia , Mirante Clara , Sousa Pinto de , Barros Henrique , Nery Susana , Brito Miguel 
Published: June 2019

Abstract

Background
Schistosomiasis and soil-transmitted helminths (STH) infections are major public health problems. We aimed to study the 6-mo impact of mass drug administration with praziquantel and albendazole on urinary schistosomiasis and STH.

Methods
We examined children (aged 2–15 y) from one hamlet, who provided urine and faeces samples at baseline (n=197), 1 mo (n=102) and 6 mo (n=92); 67 completed the protocol.

Results
At baseline, 47/67 (70.1%) children presented Schistosoma haematobium (75.8% in the baseline total sample) and 12/67 (17.9%) with STH (30.5% in the initial sample, p=0.010). Among the children, 47.3% had heavy Schistosoma haematobium infection. The most frequent STH was Trichuris trichiura in 9.0%. We also found Hymenolepis nana (13.2%) and Plasmodium falciparum (9.1%) infections and anaemia (82.1%). One mo after chemotherapy there was a significant (p=0.013) reduction of Schistosoma haematobium prevalence (23.5%) and a high egg reduction rate (86.9%). Considering the sample of 67 children, the mean egg concentration was 498 at baseline, 65 at 1 mo and 252 at 6 mo (p&lt;0.05). We also observed a reduction in STH infections, 50% in Ascaris lumbricoides, 33.3% in T. trichiura and 50% in hookworms. At 6 mo, the prevalence of Schistosoma haematobium (76.1%) was similar to the baseline and the STH reduction was not significant.

Conclusions
Longitudinal studies have reported many losses in these settings, but we were able to show that mass drug administration for control of schistosomiasis and STH present low effectiveness, that reinfections occur rapidly and that stand alone anthelmintic therapy is not a sustainable choice.
Clinical trial cohort selection based on multi-level rule-based natural language processing system
Authors: Chen Long , Gu Yu , Ji Xin , Lou Chao , Sun Zhiyong , Li Haodan , Gao Yuan , Huang Yang 
Published: June 2019

Abstract

Objective
Identifying patients who meet selection criteria for clinical trials is typically challenging and time-consuming. In this article, we describe our clinical natural language processing (NLP) system to automatically assess patients’ eligibility based on their longitudinal medical records. This work was part of the 2018 National NLP Clinical Challenges (n2c2) Shared-Task and Workshop on Cohort Selection for Clinical Trials.

Materials and Methods
The authors developed an integrated rule-based clinical NLP system which employs a generic rule-based framework plugged in with lexical-, syntactic- and meta-level, task-specific knowledge inputs. In addition, the authors also implemented and evaluated a general clinical NLP (cNLP) system which is built with the Unified Medical Language System and Unstructured Information Management Architecture.

Results and Discussion
The systems were evaluated as part of the 2018 n2c2-1 challenge, and authors’ rule-based system obtained an F-measure of 0.9028, ranking fourth at the challenge and had less than 1% difference from the best system. While the general cNLP system didn’t achieve performance as good as the rule-based system, it did establish its own advantages and potential in extracting clinical concepts.

Conclusion
Our results indicate that a well-designed rule-based clinical NLP system is capable of achieving good performance on cohort selection even with a small training data set. In addition, the investigation of a Unified Medical Language System-based general cNLP system suggests that a hybrid system combining these 2 approaches is promising to surpass the state-of-the-art performance.
Effect of ruminally protected arginine and lysine supplementation on serum amino acids, performance, and carcass traits of feedlot steers1
Authors: Teixeira Priscilla Dutra , Tekippe Jessica A , Rodrigues Liziana Maria , Ladeira Marcio Machado , Pukrop Josey R , Kim Y H Brad , Schoonmaker Jon P 
Published: June 2019

Abstract
One hundred twenty Angus × Simmental steers [322 ± 4.8 kg initial body weight (BW)] were blocked by BW and randomly allocated to 4 treatments arranged as a 2 × 2 factorial to evaluate the effects of supplemental arginine (none or 63 g/d of a 15.6% metabolizable arginine), supplemental lysine (none or 40 g/d of a 25% metabolizable lysine), and their interaction on performance and carcass composition of feedlot steers during a 170-d feeding period. The basal diet [dry matter (DM) basis] contained 52% dry-rolled corn, 22% dried distillers grains with solubles, 20% corn silage, and 6% vitamin-mineral supplement. Lysine balance was estimated to be −10.3 to −10.8 g for diets that did not contain supplemental lysine, and arginine supply was estimated to be +9.7 g for diets that did not contain supplemental arginine during period 1 (days 0 to 87). Lysine and arginine supplies met or exceeded requirements in period 2 (days 88 to 170). Rumen-protected arginine and lysine were top dressed daily until slaughter at a common BW (622 ± 5.5 kg). Data were analyzed using the MIXED procedure of SAS. Body weight, average daily gain, and DM intake were not affected (P ≥ 0.14) by arginine or lysine supplementation. However, lysine increased gain:feed (P = 0.05) during period 1. Lysine decreased serum urea nitrogen (P = 0.03) on day 87, increased (P = 0.01) longissimus muscle (LM) area, decreased (P ≤ 0.01) fat thickness and yield grade, and tended (P = 0.06) to increase moisture content of LM steaks. There tended to be an interaction for moisture content of steaks (P = 0.09), where arginine supplementation increased moisture content to a greater extent in steaks from cattle supplemented with lysine compared with steaks from cattle not fed supplemental lysine. Arginine tended to increase the proportion of Choice grade carcasses (P = 0.09) but did not change lipid content of steaks (P = 0.59). Arginine tended to decrease serum glutamate (P = 0.09) and lysine (P = 0.07) after 87 d of feeding. In conclusion, supplemental rumen-protected arginine and lysine did not improve performance, but lysine can increase carcass muscle and leanness, and although arginine did not increase lipid content of steaks, it may favorably shift carcasses to a greater quality grade.
Older Refugees in Germany: What Are the Reasons for the Difficulties in Language-learning?
Authors: Al Ajlan Ahmad 
Published: June 2019

Abstract
Learning the German language plays a central role in the integration of refugees in Germany. However, older refugees in particular often face learning difficulties, hindering their efficient integration. Based on qualitative interviews with five low-educated older refugees, five highly educated older refugees and five language teachers, I find that the core of the problem is the meaning that policymakers ascribe to refugees as a homogeneous group and to the need to teach refugees the German language as a temporary phenomenon. Moreover, there is a contradiction in the meaning that the language teachers and the older refugees ascribe to old age. While the language teachers doubt the ability and the readiness of older refugees to learn due to the difficulties that they face, older refugees do not attribute a negative meaning to old age and they do not doubt their ability or their readiness to learn the German language.
The Sexual Clock: Middle-Aged American Women and Sexual Vitality in the 1960s and 1970s
Authors: Paris Leslie 
Published: June 2019

Abstract
In the wake of the “sexual revolution” of the 1960s and 1970s, a new American consensus emerged both that women’s sexual lives remained important past their youth and that women’s sexual pleasure generally increased into middle age. Challenging the idea that older people were (or ought to be) asexual, mainstream pundits suggested ways to retain or even improve one’s sexual vitality into middle age and beyond, and argued that sex itself was both physically and emotionally rejuvenating. New attitudes toward middle-aged women’s sexuality did not entirely supplant a more traditional body project whose focus was physical maintenance, the appearance of youthfulness, and a nostalgic return to the “true” (that is, younger) self. Yet by the 1970s, increasing numbers of middle-aged women began to consider sexual renewal as an avenue for personal and relational growth, sparked by unexpected shifts in midlife, the mainstreaming of feminist critiques of ageism, and a new ethos of self-actualization. The redefinition of sexuality as a lifelong journey enabled middle-aged women to reconsider their intimate relationships and their bodies, rethink their assumptions about age and sexual desirability, and examine their current levels of sexual satisfaction. By defying the notion that aging was inherently shameful and desexualizing for women, sexologists and feminists of the late 1960s and 1970s offered a significant challenge to the “sexual clock” and helped to redefine middle age as a time of continued growth.
The redshift-space momentum power spectrum – II. Measuring the growth rate from the combined 2MTF and 6dFGSv surveys
Authors: Qin Fei , Howlett Cullan , Staveley-Smith Lister 
Published: June 2019

ABSTRACTMeasurements of the growth rate of structure, fσ8, in the low-redshift Universe allow stringent tests of the cosmological model. In this work, we provide new constraints on fσ8 at an effective redshift of z = 0.03 using the combined density and velocity fields measured by the 2MTF and 6dFGSv surveys. We do this by applying a new estimator of the redshift-space density and momentum (density-weighted velocity) power spectra, developed in the first paper of this series, to measured redshifts and peculiar velocities from these data sets. We combine this with models of the density and momentum power spectra in the presence of complex survey geometries and with an ensemble of simulated galaxy catalogues that match the survey selection functions and galaxy bias. We use these simulations to estimate the errors on our measurements and identify possible systematics. In particular, we are able to identify and remove biases caused by the non-Gaussianity of the power spectra by applying the Box-Cox transformation to the power spectra prior to fitting. After thorough validation of our methods we recover a constraint of $f\sigma _8(z_{\mathrm{eff}}=0.03)=0.404^{+0.082}_{-0.081}$ from the combined 2MTF and 6dFGSv data. This measurement is fully consistent with the expectations of general relativity and the Λ cold dark matter cosmological model. It is also comparable and complementary to constraints using different techniques on similar data, affirming the usefulness of our method for extracting cosmology from velocity fields.
The period–luminosity relation of red supergiants with Gaia DR2
Authors: Chatys Filip W , Bedding Timothy R , Murphy Simon J , Kiss László L , Dobie Dougal , Grindlay Jonathan E 
Published: June 2019

Abstract
We revisit the K -band period–luminosity (P–L) relations of Galactic red supergiants using Gaia Data Release 2 parallaxes and up to 70 yr of photometry from AAVSO and ASAS campaigns. In addition, we examine 206 LMC red supergiants using 50 yr of photometric data from the digitized Harvard Astronomical Plate Collection. We identified periods by computing power spectra and calculated the period–luminosity relations of our samples and compared them with the literature. Newly available data tighten the P–L relations substantially. Identified periods form two groups: one with periods of 300–1000 d, corresponding to pulsations, and another with Long Secondary Periods between 1000 and 8000 d. Among the 48 Galactic objects we find shorter periods in 25 stars and long secondary periods in 23 stars. In the LMC sample we identify 85 and 94 red supergiants with shorter and long secondary periods, respectively. The P–L relation of the Galactic red supergiants is in agreement with the red supergiants in both, the Large Magellanic Cloud and the Andromeda galaxy. We find no clear continuity between the known red giant period–luminosity sequences, and the red supergiant sequences investigated here.
Halo acceleration relation
Authors: Tian (田雍) Yong , Ko (高仲明) Chung-Ming 
Published: June 2019

ABSTRACT
Recently, from the new Spitzer Photometry and Accurate Rotation Curves data, McGaugh, Lelli & Schombert reported a tight radial acceleration relation between the observed total acceleration and the acceleration produced by baryons in spiral galaxies. The relation can be fitted by different functions. However, these functions can be discerned if we express the data in the form of a halo acceleration relation. The data reveals a maximum in the halo acceleration. We examined the NFW (cusp) and Burkert (core) profiles in the context of dark matter and different parameter families of the interpolating function in the framework of modified Newtonian dynamics.
Clinical Evaluation of Cingulum Bundle Connectivity for Neurosurgical Hypothesis Development
Authors: Sweet Jennifer A , Beylergil Sinem Balta , Thyagaraj Suraj , Herring Eric Z , Drapekin Jesse E , Gao Keming , Calabrese Joseph R , Miller Jonathan P , McIntyre Cameron C 
Published: June 2019

Abstract

BACKGROUND
The cingulum bundle (CB) has long been a target for psychiatric neurosurgical procedures, but with limited understanding of the brain networks being impacted. Recent advances in human tractography could provide a foundation to better understand the effects of neurosurgical interventions on the CB; however, the reliability of tractography remains in question.

OBJECTIVE
To evaluate the ability of different tractography techniques, derived from typical, human diffusion-weighted imaging (DWI) data, to characterize CB connectivity described in animal models. This will help validate the clinical applicability of tractography, and generate insight on current and future neurosurgical targets for psychiatric disorders.

METHODS
Connectivity of the CB in 15 healthy human subjects was evaluated using DWI-based tractography, and compared to tract-tracing findings from nonhuman primates. Brain regions of interest were defined to coincide with the animal model. Tractography was performed using 3 techniques (FSL probabilistic, Camino probabilistic, and Camino deterministic). Differences in connectivity were assessed, and the CB segment with the greatest connectivity was determined.

RESULTS
Each tractography technique successfully reproduced the animal tracing model with a mean accuracy of 72% (68-75%, P < .05). Additionally, one region of the CB, the rostral dorsal segment, had significantly greater connectivity to associated brain structures than all other CB segments (P < .05).

CONCLUSION
Noninvasive, in vivo human analysis of the CB, using clinically available DWI for tractography, consistently reproduced the results of an animal tract-tracing model. This suggests that tractography of the CB can be used for clinical applications, which may aid in neurosurgical targeting for psychiatric disorders.
Opioid Prescribing Laws Are Not Associated with Short-term Declines in Prescription Opioid Distribution
Authors: Davis Corey S , Piper Brian J , Gertner Alex K , Rotter Jason S 
Published: June 2019

Abstract

Objective
To determine whether the adoption of laws that limit opioid prescribing or dispensing is associated with changes in the volume of opioids distributed in states.

Methods
State-level data on total prescription opioid distribution for 2015–2017 were obtained from the US Drug Enforcement Administration. We included in our analysis states that enacted an opioid prescribing law in either 2016 or 2017. We used as control states those that did not have an opioid prescribing law during the study period. To avoid confounding, we excluded from our analysis states that enacted or modified mandates to use prescription drug monitoring programs (PDMPs) during the study period. To estimate the effect of opioid prescription laws on opioid distribution, we ran ordinary least squares models with indicators for whether an opioid prescription law was in effect in a state-quarter. We included state and quarter fixed effects to control for time trends and time-invariant differences between states.

Results
With the exception of methadone and buprenorphine, the amount of opioids distributed in states fell during the study period. The adoption of opioid prescribing laws was not associated with additional decreases in opioids distributed.

Conclusions
We did not detect an association between adoption of opioid prescribing laws and opioids distributed. States may instead wish to pursue evidence-based efforts to reduce opioid-related harm, with a particular focus on treatment access and harm reduction interventions.
The Apathy Syndrome: How We Are Trained Not to Care about Politics
Authors: Zhelnina Anna 
Published: June 2019

AbstractThe role of emotions in social movements and mobilization has been an important focus of recent research, but the emotional mechanisms producing apathy and non-participation remain under studied. This article explores the thinking and feeling processes involved in the production of apolitical attitudes, paying particular attention to their social and cultural context. Cultural norms of appropriateness and emotional expression can hinder or boost the emotions involved in the mobilizing processes. Based on 60 interviews with young people in two Russian cities, collected during and in the aftermath of the anti-regime protests of 2011–12, I explore the apathy syndrome—a combination of emotional mechanisms and cultural norms that produce political apathy. Personal frustrating experiences develop into long-term cynicism and disbelief in the efficacy of collective action, a process exacerbated by the transmission of apathy in families and educational institutions, as well as by cultural norms of appropriate emotions. Cultural clichés and dissociation from others help people cope with the trap and justify inaction.
The impact of delayed switch to second-line antiretroviral therapy on mortality, depending on failure time definition and CD4 count at failure
Authors: Bell-Gorrod Helen , Fox Matthew P , Boulle Andrew , Prozesky Hans , Wood Robin , Tanser Frank , Davies Mary-Ann , Schomaker Michael 
Published: June 2019

ABSTRACTBackgroundLittle is known about the functional relationship of delaying second-line treatment initiation for HIV-positive patients and mortality, given a patient’s immune status.MethodsWe included 7255 patients starting antiretroviral therapy between 2004-2017, from 9 South African cohorts, with virological failure and complete baseline data. We estimated the impact of switch time on the hazard of death using inverse probability of treatment weighting (IPTW) of marginal structural models. The non-linear relationship between month of switch and the 5-year survival probability, stratified by CD4 count at failure, was estimated with targeted maximum likelihood estimation (TMLE). We adjusted for measured time-varying confounding by CD4 count, viral load and visit frequency.Results5-year mortality was estimated as 10.5% (2.2%; 18.8%) for immediate switch and as 26.6% (20.9%; 32.3%) for no switch (49.9% if CD4 count<100 cells/mm3). The hazard of death was estimated to be 0.40 (95%CI: 0.33-0.48) times lower if everyone had been switched immediately compared to never. The shorter the delay in switching, the lower the hazard of death, e.g. delaying 30-60 days reduced the hazard 0.52 (0.41-0.65) times, and 60-120 days 0.56 (0.47-0.66) times.ConclusionsEarly treatment switch is particularly important for patients with low CD4 counts at failure.