bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recalibrating Reform
Authors: Cabrini Michele 
Published: April 2018

The opera Telemaco, with a libretto by Marco Coltellini and music by Christoph Gluck, occupies a unique position as an opera seria that negotiates both tradition and reform. Scholars have long criticized the opera because of its ill-shaped libretto and uneven musical setting. This article contributes to the ongoing debate about operatic reform by reevaluating Telemaco based on its literary sources—Homer’s Odyssey and Fénelon’s novel Télémaque (1699).
The absorption of Homer and Fénelon into the fabric of Telemaco goes well beyond adaptation, touching both its general dramaturgy and the specific creation of its characters. Set on the island of Circe, Coltellini's libretto echoes the timeless, liminal status of the corresponding islands (Circe’s and Calypso’s) found in Homer and Fénelon. The characters reflect and blend features of their literary counterparts. They fall into two groups: those who fight their captive condition through impetuous behavior (Circe and Telemachus) and those who attempt to circumvent their predicament by clinging to a golden past (Asteria) or yearning for a hopeful future (Ulysses’s desire to return home). Gluck’s expression of the characters’ longing and identity, achieved through a manipulation of form and textual re-composition, thus implies multiple temporal directions, suggesting a series of synchronic, revolving points of view that challenge the diachronic unfolding of events typically associated with opera reform in the eighteenth century. This method of analysis therefore offers insight into the creative process and helps refine our understanding of reformist opera, both in Gluck’s output and broader eighteenth-century operatic practice.
Optimal control for a higher-order nonlinear parabolic equation describing crystal surface growth
Authors: Duan Ning , Zhao Xiaopeng 
Published: April 2018

In this paper, we shall study the optimal control of the initial-boundary value problem of a higher-order nonlinear parabolic equation describing crystal surface growth. The existence and uniqueness of weak solutions to the problem are given. According to the variational method, optimal control theories and distributed parameter system control theories, we can deduce that the norm of the solution is related to the control item and initial value in the special Hilbert space. The optimal control of the problem is given, the existence of optimal solution is proved and the optimality system is established.
Engineering star-shaped lactic acid oligomers to develop novel functional adhesives
Authors: Santos João M.C. , Travassos Diana R.S. , Ferreira Paula , Marques Dina S. , Gil Maria H. , Miguel Sónia P. , Ribeiro Maximiano P. , Correia Ilidio J. , Baptista Cristina M.S.G. 
Published: April 2018

Abstract
O conceito de imaginação e sua vinculação ao conceito de religião na obra de Rubem Alves
Authors: Veliq Fabiano 
Published: April 2018

O debate sobre a religião é algo que permeia a história da filosofia e é tratado por muitos filósofos sob diferentes aspectos. No entanto, percebe-se que vários deles vinculam a religião a algo completamente humano. Apenas o ser humano faz religião. E é a partir desse pressuposto que Rubem Alves partirá para formular o seu conceito de religião. Para isso fará uso do conceito de imaginação para mostrar como que a religião se vincula de forma íntima a tal conceito. Neste artigo,pretende-se evidenciar o conceito de imaginação na obra de Rubem Alves e mostrar como que tal conceito é crucial na construção do seu conceito de religião.
Preparing Professionals for Working in Multicultural and Democratic Europe: Two Pedagogical Programs – Their Assessment and Collaborations
Authors: Golubeva Irina , Guntersdorfer Ivett Rita 
Published: April 2018

There has been continuous debate concerning policies and practices regarding intercultural education in the multicultural Europe and intercultural competence has become one of the crucial issues today. There is an urgent need to educate students about the limitations of using their own cultural frame to interpret and evaluate people belonging to a different cultural background. For quite long intercultural communication courses were typically offered for students in Education, International Relations, Business, and a like programs, while this subject was out of scope until the last few years in other disciplines. However, recent social and political changes are forcing program developers to work on a general intercultural preparation of professionals from all backgrounds.
There is an educational need to focus on how to prepare interculturally competent students, to act in a drastically changing society as true global citizens, who have a motivation for civic engagement and contribute to their community. More than that, according to the new framework by the Council of Europe, there is a political need for the new generation of young people to get involved with the democratic society in an active way (Council of Europe, 2016).
This paper presents two similar structures for a long-term intercultural program, where civic mindedness receives an important scope (Guntersdorfer and Golubeva, 2017). These programs can be offered to students from all disciplines in higher education. Both educational efforts aim to broaden knowledge of the meaning of culture by providing students with theories from linguistics, psychology, sociology, ethnology, and political science. Although pedagogical set-up slightly differ, there is a strong motivation for cooperation. The following article provides a description of the theoretical and pedagogical concepts of these two programs, draws on research plans and assessment methods, and lays down the groundwork for a collaboration.
Delayed Autoimmune Toxicity Occurring Several Months After Cessation of Anti-PD-1 Therapy
Authors: Parakh Sagun , Cebon Jonathan , Klein Oliver 
Published: April 2018

Abstract
Treatment with anti-programmed cell death protein 1 (PD-1) antibodies has demonstrated clinical efficacy in a whole range of malignancies including advanced melanoma, renal cell cancer, bladder cancer, and non-small cell lung cancer. Immune-related adverse events are a unique side effect of checkpoint regulator therapy including anti-PD-1 antibodies. Treatment-related autoimmunity can occur in any organ system, with the median onset usually within 5–15 weeks from the commencement of therapy, depending on the organ system involved. This study describes for the first time a case of delayed autoimmunity occurring 8 months after discontinuing treatment with the anti-PD-1 antibody nivolumab in a patient with metastatic melanoma. The case highlights the need for ongoing surveillance of patients treated with immune checkpoint inhibitors even after cessation of therapy, especially as patients increasingly stop treatment after achieving durable responses.
DIABETES TIPO MODY: ABORDAGEM PERANTE OS DESAFIOS DIAGNÓSTICOS
Authors: Rocha Mateus Henriques Leite , Oliveira Matheus Ferreira de , Weber Kassia Daniella Brandini , Lima Matheus Fonseca , De Paula Fernando Silvério , Benvindo Letícia Rodrigues , Sanchez Eduardo Saavedra 
Published: April 2018

Introdução: A diabetes do tipo MODY ou de início de maturidade do jovem, é um grupo heterogêneo de distúrbios de transmissão autossômica dominante, no qual o diagnóstico deve ser precoce e contribuir na melhora do plano de intervenção. Objetivos: Esclarecer, por meio de referencial teórico, os métodos diagnósticos utilizados para detecção dessa patologia. Metodologia: Revisão de literatura composta de publicações datadas de 2011 a 2017 advindas de bases de dados virtuais, analisadas pela técnica de Bardin. Resultados e Discussão: Os critérios diagnósticos sugestivos clínicos são idade menor que 25 anos, não autoimune ou resistente à insulina, sem insulinoterapia em 2 anos e sem antecedente familiar. O diagnóstico definitivo é realizado por estudo genético molecular. Conclusão: É admissível o aconselhamento médico para busca do diagnóstico peremptório após exclusão de diabetes tipo 1 e 2. Por ser diagnosticada definitivamente por estudo genético molecular, exige-se dos profissionais envolvidos melhor e mais amplo conhecimento para proporcionar tratamento adequado ao paciente, viabilizando a prevenção de complicações.
Palavras-chaves: Diabetes mellitus; Diagnóstico; Hiperglicemia.
Team Approach: The Management of Infection After Total Knee Replacement
Authors: Yan Chun Hoi , Arciola Carla Renata , Soriano Alex , Levin L. Scott , Bauer Thomas W. , Parvizi Javad 
Published: April 2018

* Diagnosis and management of infection after total knee arthroplasty are challenging. They require a multidisciplinary team approach, much like the management of musculoskeletal tumors.* Patients presenting with suspected infection after total knee arthroplasty require diagnostic confirmation, medical optimization, comprehensive surgical care that may include measures to cover the soft tissues, administration of long-term antibiotics, and extended rehabilitation to improve outcome.* Surgeons should work closely with infectious disease specialists or microbiologists at every step to minimize the perioperative risks of reinfection, should decide on the most appropriate surgical modality and antibiotic regime, and should monitor the response to therapy.* The current evidence on the best surgical management of infection after total knee arthroplasty (debridement and retention of prostheses compared with 1-stage exchange or 2-stage exchange arthroplasty) is lacking. Randomized, prospective studies that are under way may provide this much-needed information.
Outcomes of Anatomic Total Shoulder Arthroplasty with B2 Glenoids
Authors: Luedke Colten , Kissenberth Michael J. , Tolan Stefan J. , Hawkins Richard J. , Tokish John M. 
Published: April 2018

Background:Total shoulder arthroplasty remains an effective procedure for shoulder pain relief. Despite the negative effect of abnormal glenoid morphology and specifically retroverted and posteriorly subluxated glenoids, there is no consensus for management of B2 glenoids in total shoulder arthroplasty. The purpose of this study was to compare the outcomes and complication rates for B2 glenoid techniques so as to provide a baseline understanding of the current state of treatment of this pathology.Methods:A systematic review evaluating outcomes of total shoulder arthroplasty with biconcave glenoids using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology included searches up to December 31, 2015, of PubMed, Embase, MEDLINE, Cochrane Reviews, and Google Scholar. Nine articles met inclusion and exclusion criteria.Results:In this study, 239 total shoulder arthroplasties with B2 glenoids with a mean follow-up of 55.5 months (range, 24 to 91 months) were included. The mean patient age was 63.3 years (range, 55.8 to 68.7 years). Asymmetric reaming was performed in 127 glenoids, posterior bone-grafting was included in 53 glenoids, and 34 received an augmented glenoid component to correct glenoid retroversion and bone loss. Overall, the mean Constant and Neer scores improved from preoperative measures. Fifty-eight percent of patients had no loosening, and 42% had some loosening, although not all of these patients were symptomatic. Despite variation in outcome measures hindering treatment approach comparison, the posteriorly augmented glenoid was generally reported to provide better outcomes with few complications. Although posterior glenoid bone-grafting results in acceptable outcomes, it also represents the highest rate of complications. The revision rate was 15.6% for asymmetric reaming, 9.5% for posterior glenoid bone-grafting, and 0% for posteriorly augmented glenoids.Conclusions:Surgical treatment of the B2 glenoid remains a challenge to the shoulder surgeon, with worse outcomes and higher complication rates. Longer follow-up, consistent outcome measures, and result stratification based on glenoid type may allow for direct comparison in the future.Level of Evidence:TherapeuticLevel IV. See Instructions for Authors for a complete description of levels of evidence.
Comparison of Decline Curve Analysis DCA with Recursive Neural Networks RNN for Production Forecast of Multiple Wells
Authors: Sun J. , Ma X. , Kazi M. 
Published: April 2018

Abstract
Production forecast can significantly influence field development planning and economic evaluation. Traditional methods including numerical simulations and decline curve analysis models (DCA) requires extensive domain knowledge or lack of flexibility in modeling complex physics. However, data-driven techniques using recursive neural networks (RNN) have proven very efficient and accurate in time-series forecasting related applications. This study implemented and compared RNN with DCA in production forecast of single and multiple wells.
A typical RNN based long short-term memory (LSTM) models were first developed with various input and output sequences. Then, well-known DCA models such as Duong, Stretched Exponential Decline (SEPD), Power Law Exponential Decline (PLE) were implemented as reference solutions. Moreover, data cleaning process involves preparation of history production rates and well constraints for existing wells. For multiple wells, similar input parameters were aggregated together for adjacent wells before declining forecast using the former model. Finally, hold-out training and validation were performed, followed by comparison of model accuracy and efficiency.
Various LSTM based sequence-to-sequence models such as one-to-one, many-to-one, and many-to-many were successfully implemented for production forecast. Feature engineering was performed to generate additional features to facilitate training process. It was observed better agreement for the blind-forecasting validation dataset (i.e., last 20% of the given history) between LSTM model prediction and history production than DCA based models. LSTM models captured the overall trend whereas DCA only produced smooth curves. In addition, LSTM based models yielded good matches for all three-phase rates whereas DCA was usually limited to a certain phase. Moreover, for multiple wells, a group of neighboring wells with variable history lengths were used for training the model to forecast the production rates, where the modeling process is similar as character translation in natural language processing. Finally, it was demonstrated that the developed RNN based sequence-to-sequence models will be readily extended to model other time-series related problems such as condition-based maintenance and failure prediction.
This study proposed a novel approach to model time-series related problems (e.g., production forecast) using the RNN based sequence-to-sequence models. The developed data-driven approach makes the process of history matching and forecasting efficiency and accurate for assets with or without decent operation history information. In addition, the algorithms and case studies herein were developed with open-source libraries, which could be readily incorporated into either in-house or commercial packages.
Spatiotemporal variability and empirical Copula-based dependence structure of modeled and observed coupled water and energy fluxes
Authors: Soltani Mohsen , Laux Patrick , Mauder Matthias , Kunstmann Harald 
Published: April 2018

AbstractThe spatial variations of water and energy budgets are highly influenced by the heterogeneity of land-surface characteristics. We investigate the spatiotemporal variability and dependence structure patterns of water and energy fluxes along an elevation gradient. Our analysis is based on the application of the GEOtop model and empirical Copulas. It is performed for the Rott (∼55 km2) and Upper-Ammer (∼300 km2) catchments in the TERrestrial ENvironmental Observatories prealpine region over two recent summer episodes, as a test case. We found that GEOtop is capable of quantifying the spatiotemporal variability of the water and energy budgets with consideration for the elevation-gradient effect of this heterogeneous landscape, which is confirmed by the linear statistical metrics. Furthermore, the empirical Copula-based function reveals that the dependence structures between the measured and simulated hydrometeorological variables are similar either at upper or lower density maxima. This suggests a reasonable performance of the model, as the interaction of variables is described properly; however, the model shows poorer performance in the middle ranks of the data. It is concluded that the presented Copula-based model performance analysis is a valuable complement to traditional global performance model analyses.
A new early warning drought index for Ethiopia
Authors: Tadesse Yonas , Amsalu Aklilu , Billi Paolo , Fazzini Massimiliano 
Published: April 2018

Abstract
This study investigates the occurrence of droughts in the Dire Dawa area of eastern Ethiopia. A new index based on the rainfall delay (Rd) with respect to the expected onset (and traditional) seeding time and other indices, i.e., the aridity index and the Z-score, alternatives to the Standard Precipitation Index (SPI), are used to test the validity of the new Rd index in identifying severe droughts extending back to 1955. Although only data of rain gauges located in the district of Dire Dawa were used, they proved, albeit with different accuracies, able to identify nation-wide droughts.
Validating the AquaCrop model for maize under different sowing dates
Authors: Raja Waseem , Kanth Raihana Habib , Singh Purshotum 
Published: April 2018

Abstract
The crop growth simulation driven by daily climatic data can be used to predict the yield under varied climatic conditions. The simulation model can be exploited to reduce production risk and to evaluate the effect of soil, water, field management and climate on crop production. In this study, the FAO AquaCrop model was calibrated and validated for maize under varied sowing dates during 2012 and 2013. The experiment was conducted at Shalimar Campus of Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir during kharif seasons of 2012 and 2013. Calibration was done using data of 28 April sowing of 2012 and validation was done by using data of 10 May and 25 May sowing of 2012, and 28 April, 10 May and 25 May sowing of 2013. The simulated grain yield and crop water use was acceptable as root mean square error (RMSE) between simulated and measured observations was low (≤0.05 t ha−1 and ≤16.72 mm) with high coefficient of efficiency (0.99 and 0.71), respectively. The model also performed satisfactorily for the canopy cover and in-season biomass under varied sowing dates having RMSE ≤9.97% and ≤1.78 t ha−1, respectively.
Impact of effluents from a copper–cobalt processing plant in the environment
Authors: Bwapwa Joseph K. 
Published: April 2018

AbstractThe new concentrator of Kipushi (NCK) in Katanga province is located in the southeast of the Democratic Republic of the Congo. This processing plant produces a concentrate of copper and cobalt, and it also generates a large amount of effluents equivalent to 2,500 m3/h. The complex nature of these effluent has become a threat to human lives, vegetation, as well as to freshwater resources in the surrounding areas. During this investigation, it was found that NCK effluents have high turbidity and high levels of sulphates compared with EPA standards. These sulphates originate from acid mine water used as one of the components for the flotation process. Also, high chlorides compared with EPA standards and hardness levels due to high concentrations of calcium and magnesium were recorded. Furthermore, the effluents contain heavy metals such as zinc, copper, cobalt, lead, ion, cadmium, and arsenic. Water used during flotation and downstream processes to produce copper and cobalt concentrates was a mixture of raw water from Kamalenge pond and acid mine water from Kipushi mine in a volume ratio of 70/30 respectively. However, it was found that the mine water is the major contributor to the effluent contamination.
Dynamic characterization of a FeCl3-dosed anaerobic membrane bioreactor (AnMBR) treating municipal wastewater
Authors: Dong Qirong , Parker Wayne , Dagnew Martha 
Published: April 2018

Abstract
A transient study was conducted at pilot scale to assess the impact of Fe dosage on the dynamics of biological and membrane performance of an anaerobic membrane bioreactor (AnMBR) treating authentic municipal wastewater. A transient model of the AnMBR system was employed to assist with interpretation of the observed responses in the mixed liquor under different FeCl3 dosages. A high dosage (43 mg FeCl3/LSewage) resulted in a significant accumulation of fixed suspended solids and volatile suspended solids (VSS) and reduction of colloidal COD in the mixed liquor. The elevated dosages appeared to reduce the biodegradability of VSS that was present in the raw wastewater. Intermediate dosages of FeCl3 (21–12 mg/L) had less effect on these responses and did not appear to affect VSS biodegradation. Membrane performance was significantly affected by FeCl3 dosage as indicated by reversible resistance (RR) and physically irreversible resistance (IR). RR was closely related to the colloidal COD in the mixed liquor, thus responded quickly to Fe dosage. Physically, IR had a delayed response to changes in the colloidal COD concentrations in the mixed liquor and this was attributed to the effect of slow mass transfer of colloidal matter between the mixed liquor and the membrane.
Study of hybrid membrane filtration and photocatalysis for removal of perfluorooctanoic acid (PFOA) in groundwater
Authors: Boonya-atichart Apisara , Boontanon Suwanna Kitpati , Boontanon Narin 
Published: April 2018

Abstract
Groundwater contamination in Thailand from leaking of leachate due to improper solid waste disposal can cause contamination by PFOA (one of the perfluorinated compounds). This study proposed a new idea for the removal of PFOA from groundwater using a combination of membrane filtration and photocatalysis. Spiked groundwater samples were treated by nanofiltration and the rejected part was sent to a UV contact tank for photocatalysis. All samples were analyzed by high-performance liquid chromatography-tandem mass spectrometer (HPLC-MS/MS). The results showed that the removal efficiency of nanofiltration was 99.62%, and the rejected part was degraded by photocatalysis at an efficiency of 59.64%. Thus, the contaminants released to the environment were only 34.23%, which is around three times lower than nanofiltration alone. The results of this technical feasibility study proved that hybrid membrane filtration and photocatalysis are able to remove and degrade the contaminants in the rejected part significantly before being released to the environment, which has been the biggest gap in the processing of membrane filtration, and should be studied further in other aspects, such as fouling effects, energy consumption, and operating costs in a long-term pilot run.