bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of 5vs5 Training Games and Match-Play Using Microsensor Technology in Elite Basketball
Authors: Svilar Luka , Castellano Julen , Jukic Igor 
Published: September 2018

Abstract
Svilar, L, Castellano, J, and Jukic, I. Comparison of 5vs5 training games and match-play using microsensor technology in elite basketball. J Strength Cond Res 33(7): 1897–1903, 2019—The aim of this study was to compare the data obtained using microsensor technology in 2 types of 5vs5 training games—the regular-stop game (RSG) and the no-stop game (NSG)—and in match-play (MP) in elite basketball. Sixteen top-level basketball players were monitored during pre- and in-season periods (10 weeks). The variables included: player load, accelerations (ACC), decelerations (DEC), changes of direction (CoD), and jumps (JUMP)—all in both total (t) and high-intensity (h) relative values (i.e., per minute of play): PLmin, ACCmin, DECmin, CoDmin, and JUMPmin, respectively. Almost all variables showed trivial difference between MP and RSG. The only variable that showed small difference was tACCmin (MP > RSG). In case of RSG vs. NSG, 3 variables showed trivial difference—tACCmin, hACCmin, and hDECmin, 3 (i.e., hCODmin, tDECmin, and PLmin) small differences, and 3 (tCoDmin, tJUMPmin, and hJUMPmin) moderate differences (NSG > RSG). In MP vs. NSG, 2 variables (hCoDmin and tACCmin) showed trivial differences; variable hDECmin showed small difference, whereas the other 5 variables (tCoDmin, tJUMPmin, hJUMPmin, tDECmin, and PLmin) showed moderate difference (NSG > MP). Only one variable, hACCmin, showed moderate difference, when MP > NSG. The main conclusion of the study was that by introducing some constraints into 5vs5 tasks, the coaching staff could elicit higher physical demands than those occurring in MP. By understanding the differences in demands of NSG, RSG, and MP, coaches in elite basketball can improve their system of training drills selection, especially when looking for optimal short-term tapering approach, leading up to the game day.
Comparison of Physical Fitness Parameters for Starters vs. Nonstarters in an NCAA Division I Men's Lacrosse Team
Authors: Sell Katie M. , Prendergast James M. , Ghigiarelli Jamie J. , Gonzalez Adam M. , Biscardi Lauren M. , Jajtner Adam R. , Rothstein Alexander S. 
Published: September 2018

Abstract
Sell, KM, Prendergast, JM, Ghigiarelli, JJ, Gonzalez, AM, Biscardi, LM, Jajtner, AR, and Rothstein, AS. Comparison of physical fitness parameters for starters vs. nonstarters in an NCAA Division I men's lacrosse team. J Strength Cond Res 32(11): 3160–3168, 2018—The purpose of this study was to present a fitness profile of Division I male lacrosse players and compare the fitness attributes across different positions and starting status. Forty-one Division I men's lacrosse players (19.6 ± 1.6 years, 82.5 ± 9.5 kg, 182.0 ± 5.4 cm) volunteered to participate in the study. Fitness attributes assessed included aerobic fitness (1.5-mile run), muscular strength (1 repetition maximum bench press, squat, and hang clean), grip strength (hand dynamometer), explosive power (vertical jump), agility (3-cone drill, pro-agility), body composition (7-site skinfold), and speed (20- and 40-yard sprint). All testing was conducted by a certified strength and conditioning coach and occurred at the conclusion of pre-season training. The only significant difference across positions was for body mass, whereby defensemen were significantly heavier than attacking players (p < 0.05). Starters were significantly faster on the 3-cone drill, 20- and 40-yard sprint, and jumped significantly higher on the vertical jump compared with nonstarters (p < 0.05). Attributes pertaining to anaerobic fitness (speed, agility, and explosive power) may be better predictors of starting status than aerobic fitness in men's NCAA Division I lacrosse players. This differs from previous research on men's club lacrosse players where a difference in aerobic fitness and body composition was shown between starters and nonstarters. The normative data presented in this study may assist strength and conditioning coaches in the development of sport-specific training programs and motivate athletes toward achieving sport-specific fitness goals by helping identify areas of weakness before the start of the season.
Longitudinal Hydration Assessment in Collegiate Basketball Players Over Various Training Phases
Authors: Heishman Aaron D. , Daub Bryce D. , Miller Ryan M. , Freitas Eduardo D.S. , Bemben Michael G. 
Published: September 2018

Abstract
Heishman, AD, Daub, BD, Miller, RM, Freitas, EDS, and Bemben, MG. Longitudinal hydration assessment in collegiate basketball players over various training phases. J Strength Cond Res 35(4): 1089–1094, 2021—To the best of our knowledge, previous literature has not longitudinally examined hydration status in collegiate basketball players. Therefore, the purpose of this investigation was to examine the prepractice hydration status of collegiate basketball players across various training phases for 2 consecutive years. Retrospective analyses examined prepractice urine-specific gravity (USG) assessments obtained from National Collegiate Athletic Association (NCAA) Division I male basketball players during the preseason and competitive season, for 2 consecutive years. The first year (year 1 = Y1) of analysis consisted of 15 athletes and the second year (year 2 = Y2) consisted of 16 athletes, with 8 athletes in both seasons. Hydration status was classified based on the National Athletic Trainers' criteria: (a) euhydrated, USG < 1.020; (b) hypohydrated, USG = 1.020–1.030; and (c) significantly hypohydrated, USG > 1.030. Additional comparisons examined the association of minutes played with hydration status and changes in hydration status for athletes returning from Y1 to Y2. The results indicated 55–65.7% of cases showed levels of significant hypohydration during the preseason and competitive seasons for both years. Preseason hydration status was significantly better than the competitive season (Y1, p = 0.008; Y2, p = 0.005). Despite significant differences in minutes played (p < 0.001), no differences in hydration status were observed. Returning athletes displayed no differences in hydration status between Y1 and Y2. Collegiate basketball players show levels of hypohydration when longitudinally examined across various training phases. Although hydration may be improved in the preseason, alternative factors such as average game minutes played and length in program may not influence hydration status.
Physical Fitness and Blood Glucose Influence Performance in IndyCar Racing
Authors: Ferguson David P. , Myers Nicholas D. 
Published: September 2018

Abstract
Ferguson, DP and Myers, ND. Physical fitness and blood glucose influence performance in IndyCar racing. J Strength Cond Res 32(11): 3193–3206, 2018—Charlie Kimball (CK) is an elite-level IndyCar driver who has type 1 diabetes. Since CK became a full-time competitor, there has been exponential growth in the number of racing drivers competing with type 1 diabetes. Therefore, the purpose of this article is to present a case report of data collected on CK over 6 years, to better inform strength and conditioning coaches on how to prepare racing drivers with type 1 diabetes for competition. We hypothesized that the physical requirements to pilot the race car would include an elevated aerobic and glycolytic capacity and that blood glucose would influence key driving parameters (vertical gravitational force [Gz] tolerance and reaction time/response accuracy) related to success (finishing position). Physical fitness was evaluated with a V̇o
2max test, dual-energy X-ray absorptiometry body composition analysis, Wingate power test, and a lower-body negative pressure test for vertical Gz tolerance. To test the role of fitness and blood glucose on driving performance, heart rate (HR), breath rate (BR), and skin temperature (ST) were evaluated during practice racing sessions using the Equivital Life Monitor. Blood glucose was monitored in 47 races using a continuous glucose monitor. Driving a race car resulted in increased HR, BR, and ST. The driver's body composition, skeletal muscle power output, and aerobic capacity values were in the 10th percentile of the average population. A blood glucose range of 100–168 mg·dl−1 was identified as optimal for driving performance for the case study participant because it improved reaction time/response accuracy and Gz tolerance.
Implicit Memory for Complex Sounds in Higher Auditory Cortex of the Ferret
Authors: Lu Kai , Liu Wanyi , Zan Peng , David Stephen V. , Fritz Jonathan B. , Shamma Shihab A. 
Published: September 2018

Responses of auditory cortical neurons encode sound features of incoming acoustic stimuli and also are shaped by stimulus context and history. Previous studies of mammalian auditory cortex have reported a variable time course for such contextual effects ranging from milliseconds to minutes. However, in secondary auditory forebrain areas of songbirds, long-term stimulus-specific neuronal habituation to acoustic stimuli can persist for much longer periods of time, ranging from hours to days. Such long-term habituation in the songbird is a form of long-term auditory memory that requires gene expression. Although such long-term habituation has been demonstrated in avian auditory forebrain, this phenomenon has not previously been described in the mammalian auditory system. Utilizing a similar version of the avian habituation paradigm, we explored whether such long-term effects of stimulus history also occur in auditory cortex of a mammalian auditory generalist, the ferret. Following repetitive presentation of novel complex sounds, we observed significant response habituation in secondary auditory cortex, but not in primary auditory cortex. This long-term habituation appeared to be independent for each novel stimulus and often lasted for at least 20 min. These effects could not be explained by simple neuronal fatigue in the auditory pathway, because time-reversed sounds induced undiminished responses similar to those elicited by completely novel sounds. A parallel set of pupillometric response measurements in the ferret revealed long-term habituation effects similar to observed long-term neural habituation, supporting the hypothesis that habituation to passively presented stimuli is correlated with implicit learning and long-term recognition of familiar sounds.SIGNIFICANCE STATEMENTLong-term habituation in higher areas of songbird auditory forebrain is associated with gene expression and is correlated with recognition memory. Similar long-term auditory habituation in mammals has not been previously described. We studied such habituation in single neurons in the auditory cortex of awake ferrets that were passively listening to repeated presentations of various complex sounds. Responses exhibited long-lasting habituation (at least 20 min) in the secondary, but not primary auditory cortex. Habituation ceased when stimuli were played backward, despite having identical spectral content to the original sound. This long-term neural habituation correlated with similar habituation of ferret pupillary responses to repeated presentations of the same stimuli, suggesting that stimulus habituation is retained as a long-term behavioral memory.
Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice
Authors: Nair Remya R. , Koivisto Henna , Jokivarsi Kimmo , Miinalainen Ilkka J. , Autio Kaija J. , Manninen Aki , Poutiainen Pekka , Tanila Heikki , Hiltunen J. Kalervo , Kastaniotis Alexander J. 
Published: September 2018

There has been a growing interest toward mitochondrial fatty acid synthesis (mtFAS) since the recent discovery of a neurodegenerative human disorder termed MEPAN (mitochondrial enoyl reductase protein associated neurodegeneration), which is caused by mutations in the mitochondrial enoyl-CoA/ACP (acyl carrier protein) reductase (MECR) carrying out the last step of mtFAS. We show here that MECR protein is highly expressed in mouse Purkinje cells (PCs). To elucidate mtFAS function in neural tissue, here, we generated a mouse line with a PC-specific knock-out (KO) ofMecr, leading to inactivation of mtFAS confined to this cell type. Both sexes were studied. The mitochondria in KO PCs displayed abnormal morphology, loss of protein lipoylation, and reduced respiratory chain enzymatic activities by the time these mice were 6 months of age, followed by nearly complete loss of PCs by 9 months of age. These animals exhibited balancing difficulties ∼7 months of age and ataxic symptoms were evident from 8–9 months of age on. Our data show that impairment of mtFAS results in functional and ultrastructural changes in mitochondria followed by death of PCs, mimicking aspects of the clinical phenotype. This KO mouse represents a new model for impaired mitochondrial lipid metabolism and cerebellar ataxia with a distinct and well trackable cellular phenotype. This mouse model will allow the future investigation of the feasibility of metabolite supplementation approaches toward the prevention of neurodegeneration due to dysfunctional mtFAS.SIGNIFICANCE STATEMENTWe have recently reported a novel neurodegenerative disorder in humans termed MEPAN (mitochondrial enoyl reductase protein associated neurodegeneration) (Heimer et al., 2016). The cause of neuron degeneration in MEPAN patients is the dysfunction of the highly conserved mitochondrial fatty acid synthesis (mtFAS) pathway due to mutations in MECR, encoding mitochondrial 2-enoyl-CoA/ACP reductase. The report presented here describes the analysis of the first mouse model suffering from mtFAS-defect-induced neurodegenerative changes due to specific disruption of theMecrgene in Purkinje cells. Our work sheds a light on the mechanisms of neurodegeneration caused by mtFAS deficiency and provides a test bed for future treatment approaches.
Thoracoscopy Assisted Minimally Surgery (NUSS procedure) for Pectus Excavatum vs. Novel Modified NUSS procedure - A Single-Center Retrospective Study
Authors: Meng Lifei , Wang Mingsong 
Published: September 2018

Objective: The purpose of this article is to evaluate the efficacy of thoracoscopy assisted minimally surgery (NUSS procedure) for pectus excavatum and novel modified NUSS procedure by comparing the data of patients of pectus excavatum who had undergone novel modified NUSS Procedure or NUSS procedure.
Methods: A retrospective study was performed, involving 132 cases of patients with pectus excavatum collected from Shanghai Jiaotong University School of Medicine Xinhua Hospital cardio-thoracic surgery between Jan. 2009 and Jan. 2012. The 132 patients were strictly divided into two groups: Group A included 76 cases that underwent a novel modified NUSS procedure; Group B included 56 cases that underwent NUSS procedure. Compared data included gender, age, operative time, blood loss, postoperative hospital staying and clinical variables and demographic were compared with univariable analysis.
Results: No statistically significant correlations were observed in the two groups, such as age (12.67±4.793 years vs. 12.20± 6.423 years), sex, and other clinical data (P > 0.05). In Group A, postoperative hospitalization time (3.95±0.487 days vs. 6.07±1.412 days), operation time (46.28±12.218 minutes vs. 72.23±24.270 minutes), and blood loss (7.37±4.863 ml vs. 16.93±14.002 ml) were significantly better than those in Group B (P < 0.05), shortening hospitalization time, reducing costs, meaning statistically significant differences. There was no recurrence in Group A and Group B after operation.
Conclusion: The study demonstrated that novel modified NUSS procedure is less invasive, having rapid recovery, shortening the time of hospital stay, and reducing hospital cost. Thus, it is safe, worth promoting, and is widely being used.
Evaluation of UHRF1 and P16INK4A expression levels in newly diagnosed AML patients
Authors: Amiri Vahid , Mohammadi Mohamadhossein , Farsani Mohammad Reza Khosravi , Gharehbaghian Arshia , Hajifathali Abbas , Khazaei Zaher , Farsani Mehdi Allahbakhshian 
Published: September 2018

Introduction: Gene mutation is an infrequent cause of tumor suppressor gene (TSG) defect in de novo AML patients. Instead, it seems that leukemic cells employ epigenetic tricks to attenuate the negative impacts of intact TSGs. Ordinarily, critical TSGs, such as p16INK4A, is hyper-methylated in AML blasts under the impact of master epigenetic regulators, such as UHRF1. In this study, we investigated the correlation between UHRF1 and p16INK4A gene expression levels in newly diagnosed AML patients.
Methods: Bone marrow and peripheral blood samples were obtained from 50 newly diagnosed AML patients and 18 healthy normal control subjects. Gene expression levels of UHRF1 and P16INK4A were surveyed using SYBR Green Quantitative Real-time PCR. Statistical analyses were done using SPSS statistical software 21.0.
Results: P16INK4A gene expression showed reduced levels in 80.64% of patients above 45 years of age, while only 32% of patients below 45 years had reduced expression levels. The Spearman correlation test also demonstrated a significant negative correlation between UHRF1 and p16INK4A gene expression levels in AML patients, which was not observed in the control group (r=0.343 and P= 0.015).
Conclusion: Regarding the age-related patterns of UHRF1 and p16INK4A gene expression, and also the presence of negative correlation between them, we conclude that UHRF1 may potentially be involved in p16INK4A down-regulation in elderly AML patients, which may subsequently facilitate the progression of AML in older ages.
Cambio climático y conflictos socioambientales en ciudades intermedias de América Latina y el Caribe/ Climate change and environmental social conflicts in intermediary cities of Latin America and the Caribbean
Authors: Novillo Rameix Norha Nathalia 
Published: September 2018

Más del 50% de la población de Latinoamérica y el Caribe (LAC) habita en zonas con riesgo alto de vulnerabilidad al cambio climático. A él se asocian varias amenazas como precipitaciones extremas, deslizamientos de tierras, sequías, escasez de alimentos y riesgos para la salud. La región experimenta desde 1990 un sostenido crecimiento urbano, sobre todo en ciudades intermedias, en las que la superficie residencial informal se ha duplicado. Se ha profundizado la segregación fruto de la falta de acceso al suelo; por ello, ambas variables (informalidad y segregación) deben ser consideradas al analizar la vulnerabilidad al cambio climático en ciudades intermedias. Con base en los datos de informes técnicos recientes en este artículo se concluye que las ciudades intermedias en LAC son más sensibles a los efectos del cambio climático y, al mismo tiempo, reúnen mejores condiciones para la adaptación. Por otra parte, en el campo de los estudios urbanos se establece que existe estrecha relación entre los conflictos socioambientales y el control de los territorios, sobre todo por los cambios de uso de suelo y las externalidades relacionadas con ello. Aunque en los casos analizados no se observa una relación directamente proporcional entre conflictividad socioambiental y cambio climático en las ciudades intermedias, es evidente que las modificaciones en las condiciones climáticas a futuro podrían exacerbar los escenarios actuales.
Abstract
More than 50% of Latin America and Caribbean population lives in areas with a high risk of vulnerability to climate change. It is associated with several threats such as extreme rainfall, landslides, droughts, food shortages and health risks. Since 1990, the region has experienced sustained urban growth, especially in intermediate cities, where the informal residential area has doubled. Segregation has increased due to lack of access to land, which is why both variables (informality and segregation) should be considered when analyzing vulnerability to climate change in intermediate cities. On the other hand, in the field of urban studies, it is established that there is a close relationship between socio-environmental conflicts and the control of territories, especially due to changes in land use and the externalities related to it. Although the analyzed cases do not show a directly proportional relationship between socio-environmental conflict and climate change in intermediate cities, it is evident that changes in future climate conditions could exacerbate current scenarios.
7-10 YAŞ ARASI YÜZME YAPAN ÇOCUKLARDA ANTROPOMETRİK VE SOMATOTİP DEĞİŞKENLER
Authors: ÖZKOÇAK Vahdet 
Published: September 2018

Amaç: Spor, küçük yaşlardan itibaren
bireylerin bedensel özelliklerine etki eden bir faktördür. Bu çalışmanın amacı,
düzenli yüzme sporu yapan çocuklardaki antropometrik ve somatotipik
özelliklerin belirlenmesidir.

Materyal ve Metod: Araştırmamıza 17 Mart 2018 tarihinde TOBB
ETÜ havuzunda düzenli yüzme sporu yapan ve kulüpler adına amatör olarak yüzen
7-10 yaş arası bireyler katılımcı olarak seçilmiştir. 42 kız, 54 erkek olmak
üzere toplamda 96 bireyin katıldığı çalışmada triceps, biceps, subscapular,
suprailiac ve baldır deri kıvrımı kalınlıkları (d.k.k.), dirsek, diz, omuz,
göğüs genişliği, göğüs derinliği, üst kol, boyun ve ayakta baldır çevresi
olarak antropometrik ölçümleri alınmıştır. Antropometrik ölçüler International
Biological Programme’ın öngördüğü teknikler doğrultusunda alınmıştır. Boy ölçümü Martin tipi antropometre ile,
ağırlık ise ±100 grama duyarlı dijital tartı ile gerçekleştirilmiştir.
Ölçümlerde katılımcılar mayo giymiştir.

Bulgular: Antropometrik ölçülerde cinsiyetler arasında, diz-dirsek
genişliği ve göğüs derinliği arasında anlamlı farklılıklar gözlenmiştir (p&lt;0.05).
Somatotip kızlarda 4.7-5.1-3.0 değeri ile mezomorfik -endomorf, erkeklerde
4.2-5.7-2.8 değeri ile endomorfik mezomorf olarak bulunmuştur.

Sonuç: Katılımcıların genel olarak yağlılık
oranları yüksek bulunmuştur. Bu
nedenle bireylerin küçük yaşlarda fiziksel özelliklerinin belirlenmesi,
sağlıklı yaşam koşulları için spora yönlendirilmesi ve buna uygun beslenme
programları düzenlenmesi önemlidir.
Effect of supplementation with two combinations of alternative to antimicrobials by stages on cecal fermentation in rabbits
Authors: Liu L. , Xu Y. , Xu X. 
Published: September 2018

Antimicrobials inhibit cecal fermentation when preventing rabbit from infection. This study aimed to evaluate the effect of supplementation with two combinations of alternative to antimicrobial (combination I: 1 × 10<sup>9 </sup>cfu/kg Bacillus subtilis + 2 g/kg fructooligosaccharide; combination II: 2 g/kg acidifier and 0.6 g/kg essential oil) by stages on rabbit’s growth performance and cecal fermentation. Two hundred and forty 15-day-old male kits with similar body weight were distributed randomly to five groups, which were control (basal diet), ZnB (addition of 0.1 g/kg bacitracin zinc in basal diet), II (addition of combination II), I-II (addition of combination I during days 15–35, addition of combination II during days 36–77), and I-II-I (supplemented with combination I during days 15–35 and 57–77, supplemented with combination II during days 36–56). Each group had 6 replicates. One healthy rabbit from each replicate was slaughtered at day 35 and day 77. The results showed: (1) at day 35, the two combinations and bacitracin zinc all inhibited ileal Escherichia coli (P &lt; 0.05), decreased cecal pH, and increased total volatile fatty acid concentration (P &lt; 0.05). Combination І decreased duodenal crypt depth and increased duodenal villi height to crypt depth ratio (VCR) (P &lt; 0.05); (2) at day 77, I-II-I group had more cecal total bacteria than control (P &lt; 0.05). Mode I-II or I-II-I increased cecal Bacteroides-Prevotella (P &lt; 0.05) compared with ZnB. Mode I-II-I shortened duodenal crypt depth and increased VCR compared with control or ZnB (P &lt; 0.05); (3) after weaning, modes I-II-I and I-II had better or similar effect on decreasing diarrhoea and mortality rate compared with ZnB. In conclusion, both modes had better or similar effect on decreasing diarrhoea and mortality rate compared with inclusion of antimicrobial or combination II alone during the whole trial, and mode I-II-I showed better effect than mode I-II.