bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Receptor Tyrosine Kinase Network Regulates Neuromuscular Function in Response to Oxidative Stress in Caenorhabditis elegans
Authors: Kim Sungjin , Sieburth Derek 
Published: February 2019

Abstract
The transcription factor Nrf2 plays a critical role in the organism-wide regulation of the antioxidant stress response. The Nrf2 homolog SKN-1 functions in the intestinal cells nonautonomously to negatively regulate neuromuscular junction (NMJ) function in Caenorhabditis elegans. To identify additional molecules that mediate SKN-1 signaling to the NMJ, we performed a candidate screen for suppressors of aldicarb resistance caused by acute treatment with the SKN-1 activator arsenite. We identified two receptor tyrosine kinases, EGL-15 (fibroblast growth factor receptor, FGFR) and DAF-2 (insulin-like peptide receptor), that are required for NMJ regulation in response to stress. Through double-mutant analysis, we found that EGL-15 functions downstream of, or parallel to, SKN-1 and SPHK-1 (sphingosine kinase), and that the EGL-15 ligand EGL-17 FGF and canonical EGL-15 effectors are required for oxidative stress-mediated regulation of NMJ function. DAF-2 also functions downstream of or parallel to SKN-1 to regulate NMJ function. Through tissue-specific rescue experiments, we found that FGFR signaling functions primarily in the hypodermis, whereas insulin-like peptide receptor signaling is required in multiple tissues. Our results support the idea that the regulation of NMJ function by SKN-1 occurs via a complex organism-wide signaling network involving receptor tyrosine kinase signaling in multiple tissues.
A Cataguases de Luiz Ruffato em O mundo inimigo (2005)
Authors: Sousa Camila Galvão de , Siqueira Joelma Santana 
Published: February 2019

Este artigo analisa a representação da cidade nas narrativas-capítulos do romance contemporâneo O mundo inimigo de Luiz Ruffato, publicado em 2005 pela Editora Record. A cidade mineira Cataguases, em Minas Gerais, que na transição do século XIX para o XX, passou pelos processos de urbanização, industrialização e modernização, é o espaço central do romance e cidade natal do escritor. No entanto, Luiz Ruffato, através de uma narrativa moderna, permite que suas personagens, pertencentes à classe trabalhadora, falem por si para apresentar uma perspectiva diferente das questões destacadas em livros sobre a história da cidade, já que são impedidas de conviver na dinâmica urbana. *** The Cataguases of Luiz Ruffato in O mundo inimigo (2005) ***This article analyzes the representation of the city in the narratives-chapters of the contemporary novel Luiz Ruffato’s O mundo inimigo, published in 2005 by Editora Record. The mining town of Cataguases in Minas Gerais, which in the transition from the nineteenth to the twentieth century, went through the processes of urbanization, industrialization and modernization, is the central space of the novel and hometown of the writer. However, Luiz Ruffato, through a modern narrative, allows his characters, belonging to the working class, to speak for themselves to present a different perspective of the issues highlighted in books on the history of the city, since they are prevented from coexisting in urban dynamics.Keywords: literature and city; work in literature; contemporary Brazilian romance.
A retórica do trágico em o remorso de baltazar serapião
Authors: Alvarez Aurora Gedra Ruiz 
Published: February 2019

A partir das elaborações teóricas de Aristóteles sobre a tragédia, discute-se neste estudo o conceito de trágico, tendo como aporte teórico Albin Lesky e Peter Szondi. Para este último, o trágico é compreendido sob o enfoque filosófico que se manifesta em consonância com uma determinada cultura e um certo tempo. À luz deste pressuposto teórico e de contribuições de outros estudiosos sobre esse tema, examina-se como a linguagem, particularmente a antítese e o oximoro, enforma uma percepção de mundo trágica no discurso do protagonista de o remorso de baltazar serapião de Valter Hugo Mãe, que efeitos de sentido esses recursos estilísticos produzem nessa configuração e que olhar sobre si e sobre o mundo a personagem apresenta no romance. *** The rhetoric of the tragic in o remorso de baltazar serapião ***Based on Aristotle’s theoretical views about tragedy, the concept of tragic is discussed in this study, also taking into consideration Albin Lesky’s and Peter Szondi’s theoretical contributions. The latter understands the tragic under the philosophical approach that it is manifested in consonance with a given culture and a given time. In the light of this theoretical assumption and based on other scholars’ considerations about this theme, it is investigated how the language, having as structuring elements the antithesis and the oxymoron, shapes a tragic worldview in the protagonist’s speech of the o remorso de baltazar serapião by Valter Hugo Mãe, what effects of meaning these rhetoric resources produce in this configuration and which views about himself and the world the character shows at this novel.Keywords: tragic; o remorso de baltazar serapião; antithesis; oxymoron.
A República na obra de José Rodrigues Miguéis
Authors: Oliveira A. Paulo Dias 
Published: February 2019

O objectivo deste artigo é tentar compreender a perspectiva de José Rodrigues Miguéis em relação à República Portuguesa no período que vai de 1910 a 1926. Com esse fim em vista, procurou-se enquadrar as suas obras literárias no assunto em questão, com especial relevo para aquelas que tratam directamente desta problemática, ou seja, Escola do Paraíso, Idealista no mundo real e O Milagre segundo Salomé. Desse modo, pode-se asseverar que existem duas visões ou reflexos nas obras em análise, sendo, precisamente, esse duplo caminho que pretendemos pôr em destaque através da investigação das personagens. *** The Republic in José Rodrigues Miguéis’ work ***The main objective of this article is to understand the perspective of José Rodrigues Miguéis about the Portuguese Republic, in the period between 1910 and 1926. For this purpose, his works were framed under this subject, especially Escola do Paraíso, Idealista no mundo real and O Milagre segundo Salomé. Thereby, it can be assured that there are two visions or reflections on the analyzed works, being, precisely, this double path that is intended to be highlighted through the characters investigation.Keywords: José Rodrigues Miguéis; Republic (1910-1926); literature; history.
Identidade cultural relida: leitura e memória coletiva no romance O outro pé da sereia de Mia Couto
Authors: Franz Marcelo , Rodrigues Victor De Barros 
Published: February 2019

Analisamos a representação do ato leitor na obra O Outro Pé da Sereia (2006), de Mia Couto. O romance entende a leitura como veículo de reprocessamento da memória coletiva, termo que abordaremos sob a ótica de Maurice Halbwachs (2006). Dividida em duas épocas, (situadas nos anos de 2002 e 1560) a ação romanesca se centra na viagem realizada pelaprotagonista, Mwadia até sua comunidade de origem a fim de abrigar a estátua de uma santa comum dos pés arrancados, encontrada às margens de um rio. Junto com a imagem, ela encontrou documentos que descrevem a expedição do jesuíta D. Gonçalo para difusão do Catolicismo naÁfrica no século XVI. O contato com esses objetos resulta na recuperação e ressignificação de experiências passadas, a partir dos conteúdos lidos. Isso redefine a própria individualidade deMwadia e sua relação com a comunidade.*** Reinterpreted cultural identity: reading and collective memory in the Mia Couto’s novel O outro pé da sereia ***This paper analyzes the representation reading in the Mia Couto’s novel O outro pé da sereia (2006), Mia Couto. The novel understands reading as reprocessing vehicle of collective memory, a term which will be discussed from the perspective of Maurice Halbwachs (2006). Divided in temporal plots, situated in 2002 and 1560, the novelistic action focuses on the journey of the protagonist Mwadia till her community of origin in order to shelter the statue of a saint without one foot that was found on the banks of a river. Along with the image, she founds some documents that described the D. Gonçalo’s expedition to spread Catholicism in Africa in the sixteenth century. The contact with these objects results in the recuperation andresignification of past experiences. The reading content redefines Mwadia’s individuality andrelation with the community.Keywords: memory; reading; Mia Couto.
Elazığ yöresinde yetişen badem ağaçlarının (Prunus amygdalus Batsch) yetişme ortamı özelliklerinin belirlenmesi
Authors: AKGÜN Tuğçe Dilşad , TÜFEKÇİOĞLU Mustafa , KÜÇÜK Mehmet 
Published: February 2019

Elazığ ilinde son yıllarda badem ağaçlandırmalarına oldukça önem verilmiş ve yaygınlaştırılmıştır. Bu önem bademin sınır ağacı olarak kullanımı ve tohumdan yetiştirilebilmesinin yanı sıra ıslah çalışmalarının yapılarak bahçeler kurulması, bakımının ve budamasının yapılması ile ürün kalitesinin ve neticesinde ekonomik girdisinin artırılması ile daha da artmaktadır. Bu bağlamda çalışmada Elazığ ilinde geniş bir yayılışa sahip olan badem ağacının yetişme ortamı özelliklerinin (toprak, iklim ve yükselti) belirlenmesi hedeflenmiştir. Çalışma bademin iyi gelişim gösterdiği doğal, emekle yetiştirilen ve ağacının yaygın yayılış gösterdiği Elazığ ilinin 5 farklı yöresinde (Elazığ Merkez, Keban, Sivrice, Ağın ve Baskil) toprak örneklemesi yapılarak gerçekleştirilmiştir. Bu toprakların fiziksel ve kimyasal özelliklerine ait bulgular toprak verimliliğinin sınıflandırıldığı “sınır değerleri çizelgesine” göre değerlendirilmiştir. Toprak örnekleri üzerinde tekstür, pH, kireç, tuz, organik madde, makro (P, K, Ca, Mg) ve mikro besin elementleri (Fe, Cu, Zn, Mn) analizleri yapılmıştır. Badem ağacı yetiştiriciliği açısından değerlendirildiğinde Elazığ ili yöresi topraklarının tekstür ve tuzluluk açısından her hangi bir kısıtlayıcı etki oluşturmadığı özellikle tekstür bakımından geniş bir değişkenliğe sahip olduğu ortaya çıkmıştır. Diğer taraftan toprak reaksiyonunun hafif alkaliliği, kireç miktarının fazlalığı ve organik madde içeriğinin azlığı göze çarpan önemli hususlar olarak belirlenmiştir. Topraklara daha fazla organik madde ilavesi ile alkaliliğin ve kireç’in azaltılmasına çalışılmalıdır. Besin elementleri değerlendirildiğinde, bütün yöre topraklarının mangan y.nünden fakir olduğu, yarayışlı potasyum, bakır, çinko ve demir y.nünden yeterli olduğu belirlenmiştir. Yarayışlı fosfor, kalsiyum ve magnezyum y.nünden ise zengin olduğu tespit edilmiştir. Gübre takviyesiyle besin elementi
noksanlığı giderilebilir.
Morphological features of the corneal endothelium in patients with pseudoexfoliative glaucoma
Authors: Beletskaya Inessa S. , Astakhov Sergey Yu. , Tkachenko Natalya V. 
Published: February 2019

Purpose. To study the main morphological features of the corneal endothelium in patients with pseudoexfoliative glaucoma (PEG).
Methods. We included 193 subjects aged from 55 to 75 years. The main study group (PEG) included 96 patients (192 eyes), the primary open angle glaucoma (POAG) group included 36 patients (72 eyes) with POAG, the PEX group included 31 patients (62 eyes) with pseudoexfoliation syndrome without glaucoma. The control group consisted of 30 healthy subjects (60 eyes). Main corneal endothelium parameters were evaluated using a non-contact endothelial microscope EM-935 (Haag Streit, Switzerland). Data were analyzed by STATISTICA 9 software for Windows.
Results. The patients with PEG had lower endothelial cell density (ECD) in comparison to the control group (p 0.01), and PEX group (p 0.05). The polymegatism level in patients with PEG and POAG was higher than in the control group (p 0.001, and p 0.01, correspondingly). In patients with moderate and advanced PEG, the ECD was significantly lower (p 0.01), and the polymegatism level was significantly higher (p 0.01) than the same parameters in patients with early PEG. The lowest ECD and the highest polymegatism percentage were observed in PEG patients with more pronounced PEX manifestations, p 0.05. No effect of IOP-lowering eye drops on the corneal endothelium parameters was revealed, p 0.05.
Conclusions. Significant morphological changes of the corneal endothelium (decreased endothelial cell density, increased polymegatism percentage) were revealed in patients with PEG. It was established that the severity of these changes is associated with the PEG and PEX severity. No effect of IOP-lowering eye drops on the corneal endothelium parameters was detected.
Atributos de Influência na Tomada de Decisão de Jovens de Escolas Públicas a Cursar o Ensino Superior
Authors: Molina Obara Bruno Rafael , Fernandes Thiago , Zago Bruno Wagner , Do Berço Silva Matheus , Ballerini Larissa Regina , Schwan Carla Malu 
Published: February 2019

O objetivo deste trabalho foi identificar os principais fatores que influenciam na tomada de decisão dos jovens a ingressarem no Ensino Superior em uma Universidade Pública do município de Barra do Bugres-MT. O estudo foi realizado em duas escolas estaduais, uma localizada no perímetro urbano e outra, no perímetro rural. A metodologia estratégica de trabalho consistiu em uma análise qualitativa, privilegiando a análise das opiniões apresentadas pelos stakeholders. O instrumento de coleta de dados foi um questionário com 40 questões fechadas sobre o perfil dos participantes, seus interesses e expectativas determinantes da escolha do curso. Na análise se identificou que o principal fator influente na tomada de decisão dos jovens da E.E Reinaldo Dutra a cursarem ou não alguns dos cursos de graduação da UNEMAT foi a distância. Já os alunos da zona urbana (E.E Alfredo José), o fator prevalente mais comentado foi a oportunidade de emprego. Considera-se que os fatores citados representam um entrave que deve ser discutido com base nas políticas sociais vigentes, principalmente, as que enaltecem o acesso universal direcionado para a Universidade pública de qualidade. Desta forma, conclui-se que uma estratégia acessível e pertinente para minimizar a falta de informação a respeito do perfil do curso é a promoção de ações de extensão, que divulguem os cursos de graduação da UNEMAT, fundamentadas com explicações pontuais sobre as formas de ingresso e permanência do aluno na instituição, inserção de projetos com temáticas atrativas, envolvendo a comunidade e a escola, por meio da ascensão de feiras de ciências interdisciplinares.
Reconhecimentos, sensibilidades e relações étnico-raciais: a obrigatoriedade do ensino do Holocausto em Porto Alegre
Authors: Meinerz Carla Beatriz , Camargo Cássio Michel dos Santos 
Published: February 2019

O artigo resulta de uma escrita conjunta que tematiza as memórias ressentidas em luta por reconhecimento (ANSART, 2001) e os temas sensíveis (ALBERTI, 2013) nas prescrições legais acerca do que deva ser ensinado nas aulas de História da Educação Básica no Brasil. Parte do caso emblemático da aprovação da Lei Municipal n. 10.965/2010 que, no contexto nacional da obrigatoriedade legal do ensino da história e cultura africana, afro-brasileira, indígena e da educação para as relações étnico-raciais, torna também obrigatório o ensino do Holocausto nas escolas da rede municipal de Porto Alegre. As orientações legais, construídas na forma de políticas públicas vinculadas aos processos contemporâneos de reparação histórica, são atravessadas pelos embates do tempo presente e projetam o ensino de temas sensíveis, especificamente nessa escrita – o Racismo e o Holocausto. O artigo cruzará duas pesquisas em andamento, enfocando a historização das políticas afirmativas que atingem os currículos de História, dentro e fora do Brasil, relacionando-as com os projetos de educação das relações étnico-raciais e de educação para os direitos humanos.
Sessiz mastoidit: İki olgu sunumu
Authors: TURAN Şükrü , KAYA Ercan , PINARBAŞLI Mehmet Özgür , GÜRBÜZ Melek Kezban , İNCESULU Şaziye Armağan 
Published: February 2019

Sessiz
mastoidit mastoid hücrelerin kemik yapılarında ve mukozal tabakadaki subklinik
enfeksiyöz enflamatuar süreci tanımlamaktadır. Hayatının belli döneminde akut
otitis media (AOM) geçiren ve yanlış antibiyotik tercihi veya yetersiz dozda antibiyotik kullanımı
sonucunda hastaların kliniğinde gerileme olmasına rağmen; bakterilerin eredike
olmaması sonucunda sessiz mastoidit gelişmektedir. Bu
hastaların kliniğinde genellikle hiçbir semptom olmamakla birlikte bazı
hastalarda baş ağrısıyla karışan kulak ağrısı, mastoid bölgede duyarlılık,
işitme kaybı, kulakta dolgunluk hissi ve subfebril ateş gibi semptomlar
olabilmektedir. Sessiz mastoidit subklinik seyirli olması
ve fizik muayenede tipik bulgusunun olmaması sebebiyle gözden kaçmakta ve
hastalarda yaşam kalitesini bozan şikayetler oluşturmaktadır. Bu çalışmadaki
amacımız kliniğimizde sessiz mastoidit tanısı konularak tedavileri gerçekleştirilen
iki olgunun literatür eşliğinde tartışılması ve sessiz mastoiditin öneminin
vurgulanmasıdır.
GOAL PROGRAMMING SEBAGAI DECISION SUPPORT SYSTEM TINGKAT KESEHATAN BANK PT BANK BUKOPIN, TBK
Authors: Dewi Aprilia Sintya , Paramu Hadi , Endhiarto Tatok 
Published: February 2019

Abstract: This research aimed to analyze the changes in several objective priorities as the banking targets in the decision making process. The research applied goal programming model and based on the experiments on the financial data or ratios. The objective functions of the research were the ratios used to asses bank health level, namely: capital, Capital Adequacy Ratio (CAR), asset quality, Return on Assets (ROA), Return on Equity (ROE), Net Interest Margin (NIM), Operational Cost compared to Operating Income (BOPO) and Loan to Deposit Ratio (LDR). Results show that only capital and LDR targets achieved predominantly on a variety of priority setting. While the targets of CAR, asset quality, ROE, and NIM are not achieved predominantly on a variety of priority setting.
Keywords: Capital, CAR, Asset Quality, ROA,ROE, NIM, BOPO, LDR, Financial Health Level.
PENENTUAN STRATEGI PEMASARAN BERAS HERBAL FORTE CV AN-NAHLAH JEMBER
Authors: Yudhistira Novan 
Published: February 2019

Abstract:The purpose of this study was to identify the internal (strengths and weaknesses) and external (opportunities and threats) factors influencing the marketing of Forte Herbal Rice and to formulate alternative marketing strategies that can be used by CV. An Nahlahas the seller. The sampling method used was convenience sampling with a sample size of 32 (thirty two) respondents. The analysis tool used is the Strenghts Weaknesses Opportunities Threats (SWOT) analysis. Using external internal matrix approach, CV. An Nahlah should apply a growth strategy. The SWOT analysis resulted in 5(five) main marketing strategies, i.e., lowering product prices, increasing thepromotion activities, optimizing social media to support promotion, supplying products to the stores located near to consumers, maintaining the stock of the product for the emerging market.
Keywords: Strengths, Weaknesses, Opportunities, Threats, Marketing Strategy.
STRATEGI PENCAPAIAN OPINI WTPPEMERINTAH KABUPATEN BONDOWOSO DALAM PENERAPAN STANDAR AKUNTANSI PEMERINTAHAN BERBASIS AKRUAL
Authors: Setyawati Heny 
Published: February 2019

Abstract: New Public Management has reformed the financial management of the public sector by adopting approaches from the private sector in order to achieve organizational efficiency and effectiveness (including local and central government finances) and it was the reason behind the implementation of Accrual-based Government Accounting Standards (SAP). The Governmentof Bondowoso also implements accrual-based SAP policy. This study used a qualitative approach by using Strenghts Weaknessess Opportunities Threats (SWOT) analysis in the early stage to describe the strategy and then completed by in depth interview. The informants were 8 (eight) key persons in the Government of Bondowoso with significant roles in achieving the unqualified opinion in implementing the accrual-based SAP. Results show that commitment from the leaders of local government and institutions, financial statements presentation that in line with the SAP, sufficient internal control system, and the follow-up on the State Audit Agency’s recommendations on the local government financial statements are the major strengths in achieving the unqualified opinion of the accrual-based SAP. The opportunities in Strength-Opportunity (SO) strategy are the issuance of various laws and regulations and technical guidance of accrual-based accounting standards by the central government.
Keywords: Unqualified Opinion, Accrual Based SAP, SWOT, Strategy.
PENERAPAN CORPORATE GOVERNANCE DENGAN MENGGUNAKAN BALANCE SCORECARD PADA BANK MANDIRI JEMBER
Authors: Nugraheni Ponti Primastuti Aulia 
Published: February 2019

Abstract: Good corporate governance is a barometer of for a company accountability. A poor corporate governance implementation is presumed as one of the causes of various corporate financial business scandals. Banking companies deal directly with the provision of goods and services to meet the wants and needs of the community. In this case, the community is the customer that must be served well in order to meet their satisfaction by applying a good organizational management mindset to improve the customer (community) satisfaction. Applying the Balanced Scorecard (BSC) approach, banks will be able to explain their mission to the community, identify the indicators of public satisfaction more transparently, objective, and measurable, and identify the work processes and the quality of human resources needed to achieve their mission and vision. In the implementation process, the banking activities will produce a community-oriented strategic management system.
Keywords: Corporate Governance, Bank, BSC.
PENGARUH KOMPETENSI SUMBER DAYA MANUSIA DAN PEMANFAATAN TEKNOLOGI INFORMASI TERHADAP KUALITAS LAPORAN KEUANGAN MELALUI PENGELOLAAN BARANG MILIK DAERAH
Authors: Wahyuni Sri , Fadah Isti , Tobing Diana Sulianti 
Published: February 2019

Abstract: The purpose of this study is to analyze the influence of human resource competency and utilization of information technology on the financial statement quality mediated by the local property management in the Government of Bondowoso Regency. This is a quantitative research with the population consists of all property administrators, operators of Local Management Information System (SIMDA)/financial report makers, and Financial Administration Officials (PPK). Sampling method used is saturated sampling (census). Data used were collected from questionnaires distribution and analyzed using Structural Equation Modeling (SEM). Results of the research prove that human resource competency affects local property management and financial statement quality, while utilization of information technology only affects financial statement quality, but it has no effect on local property management. In addition, local property management affects financial statement quality. These mean that local property management partially mediates the influence of human resource competency on financial statement quality, but it does not mediate the influence of utilization of information technology on financial statement quality.
Keywords: Human Resource Competency, Utilization of Information Technology, Management of Local Property, and Quality of Financial Statement.