bluuebunny/crossref_metadata_2025_split huggingface dataset:
SINGLE-LEG HOP PERFORMANCE IS A PREDICTOR FOR PATIENT-REPORTED OUTCOMES FOLLOWING A LOWER EXTREMITY INJURY
Authors: Simon Janet E. , Yom Jae , Grooms Dustin R. 
Published: March 2019

Background: The single-leg hop for distance (SLHOP) is a commonly used functional performance measure to determine return-to-play readiness. However, it is unknown if functional performance at return-to-play can predict future patient outcomes. Therefore, the purpose of this study was to determine if SLHOP performance and symmetry at return-to-play following a lower extremity injury would predict lower extremity patient-reported outcomes six months post-injury. Methods: Two-hundred thirty-six adolescent athletes (15.7±1.4 years, 171.1±7.6 cm, 70.3±15.3 kg) were recruited for this study. If an individual sustained a non-surgical lower extremity injury during their sports season and missed three days of sports participation they were eligible for follow-up functional and patient outcome assessment Thirty-two adolescent athletes were eligible and completed the follow-up testing (15.0±1.1 years, 166.5±4.9 cm, 67.3±10.4 kg; 14 American football, 8 volleyball, 4 girls’ basketball, 6 boys’ basketball athletes). The SLHOP was completed by affixing a tape measure to the ground and instructing the participant to hop on one leg as far as possible. Each participant performed three trials per leg at return-to-play (alternating legs). To be counted as a successful trial the participant maintained postural stability for 2 seconds after the landing and the contralateral leg was not allowed to touch the ground. The Pediatric Patient-Reported Outcomes Measurement Information System (PROMIS) Lower Extremity scale was completed six months after return-to-play as the patient-reported outcome measure. A stepwise multiple linear regression was conducted to predict PROMIS Lower Extremity scale score from SLHOP distance on the injured and uninjured leg (cm), and limb symmetry (%). Results: At step one of the analysis, injured limb SLHOP distance was entered into the regression equation and was significantly related to the PROMIS Lower Extremity scale F(1,31)=20.8, p<.001. The multiple correlation coefficient was 0.79, indicating approximately 62% of the variance of the PROMIS Lower Extremity scale scores could be accounted for by the injured limb SLHOP distance. Specifically, for every increase in one cm of SLHOP performance there would be an increase of 0.6 points on the PROMIS Lower Extremity scale. Uninjured limb SLHOP distance and limb symmetry did not enter into the equation at step two of the analysis (p>.05). Conclusion: The SLHOP conducted at time of return-to-play following a lower extremity injury can predict lower extremity patient-reported outcomes six months later. This indicates that clinicians may be able to use the SLHOP following an injury to not only determine return-to-play readiness but a successful long-term outcome.
How does empagliflozin improve arterial stiffness in patients with type 2 diabetes mellitus? Sub analysis of a clinical trial
Authors: Bosch Agnes , Ott Christian , Jung Susanne , Striepe Kristina , Karg Marina V. , Kannenkeril Dennis , Dienemann Thomas , Schmieder Roland E. 
Published: March 2019

Abstract
Background
Empagliflozin has been shown to reduce cardiovascular mortality, but the underlying pathogenetic mechanisms are poorly understood. It was previously demonstrated that empagliflozin improved arterial stiffness.

Methods
Our analysis comprising 58 patients with type 2 diabetes mellitus identifies factors triggering the improvement of arterial stiffness. All patients participated in an investigator-initiated, prospective, double-blind, randomized, placebo-controlled, interventional clinical trial (http://www.ClinicalTrials.gov: NCT02471963, registered 15th June 2015, retrospectively registered) and received either 6-weeks treatment with 25 mg empagliflozin orally once daily or placebo (crossover). Central systolic pressure and central pulse pressure were recorded by the SphygmoCor System (AtCor Medical). Now, we investigated the impact of parameters of glucose metabolism, volume status, sympathetic activation, lipids, uric acid, blood pressure and inflammation on vascular parameters of arterial stiffness using multivariate regression analysis.

Results
As previously reported, therapy with empagliflozin improved arterial stiffness as indicated by reduced central systolic blood pressure (113.6 ± 12.1 vs 118.6 ± 12.9 mmHg, p < 0.001), central pulse pressure (39.1 ± 10.2 vs 41.9 ± 10.7 mmHg, p = 0.027) forward (27.1 ± 5.69 vs 28.7 ± 6.23 mmHg, p = 0.031) as well as reflected wave amplitude (18.9 ± 5.98 vs 20.3 ± 5.97 mmHg, p = 0.045) compared to placebo. The multivariate regression analysis included age, sex and change between empagliflozin and placebo therapy of the following parameters: HbA1c, copeptin, hematocrit, heart rate, LDL-cholesterol, uric acid, systolic 24-h ambulatory blood pressure and high sensitive CRP (hsCRP). Besides the influence of age (beta = − 0.259, p = 0.054), sex (beta = 0.292, p = 0.040) and change in systolic 24-h ambulatory blood pressure (beta = 0.364, p = 0.019), the change of hsCRP (beta = 0.305, p = 0.033) emerged as a significant determinant of the empagliflozin induced reduction in arterial stiffness (placebo corrected). When replacing HbA1c with fasting plasma glucose in the multivariate regression analysis, a similar effect of the change in hsCRP (beta = 0.347, p = 0.017) on arterial stiffness parameters was found.

Conclusion
Besides age and sex, change in systolic 24-h ambulatory blood pressure and change in hsCRP were determinants of the empagliflozin induced improvement of vascular parameters of arterial stiffness, whereas parameters of change in glucose metabolism and volume status had no significant influence. Our analysis suggests that empagliflozin exerts, at least to some extent, its beneficial vascular effects via anti-inflammatory mechanisms.
Trial registrationhttp://www.ClinicalTrials.gov: NCT02471963, registered 15th June 2015, retrospectively registered
Cardiopulmonary Profile of Individuals with Intellectual Disability
Authors: BOONMAN ANNE J. N. , SCHROEDER ELIZABETH C. , HOPMAN MARIA T. E. , FERNHALL BO , Hilgenkamp THESSA I. M. 
Published: March 2019

ABSTRACT

Introduction
Individuals with intellectual disabilities (ID) are often sedentary and have low fitness levels. Current knowledge supports the existence of physiological barriers resulting in low fitness and exercise intolerance in individuals with Down syndrome, which might be applicable to other ID etiologies. If physiological barriers exist in ID, this would require adaptation of the physical activity guidelines.

Purpose
The aim of this study was to assess differences in cardiopulmonary profiles, including maximal oxygen uptake, during a cardiopulmonary exercise test in individuals with ID without Down syndrome and healthy controls.

Methods
Participants performed an incremental cardiopulmonary exercise test on a treadmill until exhaustion. Outcomes were peak heart rate (HRpeak), absolute peak oxygen uptake (V˙O2peak), relative V˙O2peak, peak minute ventilation, peak CO2 expenditure, oxygen uptake efficiency slope, V˙E/V˙CO2 slope, absolute O2 pulse, relative O2 pulse, difference from predicted HRpeak, HR reserve, RERpeak, ventilatory threshold (VT), and VT as a percentage of V˙O2peak. Differences between groups were analyzed with Student’s t-tests and multiple linear regression after adjusting for potential confounders (sex, age, body mass index, and activity level).

Results
Individuals with ID had worse outcomes on all of the cardiopulmonary outcomes, except for VT expressed as a percentage of V˙O2peak and V˙E/V˙CO2 slope (P < 0.05). Having ID was an independent predictor of reduced physiologic function during exercise (P < 0.05).

Conclusion
These results demonstrate that individuals with ID present exercise intolerance potentially related to lower HRpeak and impairments in ventilatory function, and these results also suggest the possibility of peripheral muscle hypoperfusion. Existing physical activity guidelines likely underestimate the actual intensity of activity performed by individuals with ID and need to be adapted.
Diversity structure of phytoseiid mites in urban plant habitats
Authors: Grabovska S. L. , Mykolaiko I. I. , Mykolaiko V. P. , Myronyuk T. M. 
Published: March 2019

We founded that E. finlandicus and K. aberrans formed the nucleus of Phytoseiidae community on the plants of urbanized environment in the result of study of 93 plant species (55 species of tree-and-shrub (58.9%) and 38 species of herbaceous plants (41.1%). Our research was carried out in plantations along the main and secondary municipal highways, near residential area and industrial buildings, on private plots of the private building area, in city parks and squares of Kyiv, Uman, Brovary, and Vasylkiv (Ukraine). The peculiarities of their distribution among urban plant associations, which differ from each other by different characteristics (population, area, degree of urbanization) were determined. Both species - E. finlandicus and K. aberrans have a rather extended range of indicators of relative biotope contiguity (-0.91<Fij<0.43 and -0.93Fij<0.96) that indicated their property to inhabit large number of plants. The indicator of K. aberrans occurrence, which was the highest in the city with the smallest degree of urbanization (Vasylkiv), decreased in the city with the maximum possible degree of urbanization (Kyiv). This indicator of E. finlandicus on the contrary increased along the gradient from a smaller city to the metropolitan city. K. aberrans inhabit a large number of plant species (33 species), while preferred plants from Rosacea family. E. finlandicus dominated by number of urban plant species it inhabited (75 species, 79.78%), absolute number of individuals in collected samples of predatory mites (504), occurrences index (Is = 74.49%), and by index of Palii-Kovnatsi (Di = 51.42%). The dominance of E. finlandicus species was registered in both groups of plants. The distribution of Phytoseiidae’s was primarily connected with the possibility of their movement along the surface of the substrate. Speed of mites moving was not the same in different species and depended on their morphology and plant morphology. Both species lived and laid eggs on the underside of the leaf. K. aberrans was more commonly found near the central vein of the leaf, while E. finlandicus was observed more evenly on the leaf plate, which can be explained by it higher vagility. K. aberrans could inhabit high number on fruit varieties of plants with pubescence leaves. Morphological features of plant leaves did not affect the spread of E. finlandicus species, therefore, they could be considered more "universal". However, it reached a higher quantity on the plants with a smooth surface of a leaf plate. Certain temperature, illumination regime, air and soil humidity caused the differences in mites spreading at various habitats.
Inversion of the Cauchy Integral Taken over the Double Periodic Line
Authors: Khatiashvili N. 
Published: March 2019

Abstract
The Cauchy type singular integral equation is investigated when the line of integration is the union of a countable number of disconnected segments. The equation is equivalently reduced to an equation with double periodic kernel. Effective solutions having integrable singularities at the end-points of the line of integration are obtained.
Investigation of Two-Dimensional Models of Elastic Prismatic Shell
Authors: Avalishvili M. , Gordeziani D. 
Published: March 2019

Abstract
Statical and dynamical two-dimensional models of a prismatic elastic shell are constructed. The existence and uniqueness of solutions of the corresponding boundary and initial boundary value problems are proved, the rate of approximation of the solution of a three-dimensional problem by the vector-function restored from the solution of a two-dimensional one is estimated.
On the Oscillation of Solutions of First Order Differential Equations with Retarded Arguments
Authors: Grammatikopoulos M. K. , Koplatadze R. , Stavroulakis I. P. 
Published: March 2019

Abstract
For the differential equation

where 𝑝𝑖 ∈ 𝐿
loc
(𝑅+; 𝑅+), τ
𝑖 ∈ 𝐶(𝑅+; 𝑅+), τ
𝑖(𝑡) ≤ 𝑡 for 𝑡 ∈ 𝑅+, , optimal integral conditions for the oscillation of all solutions are established.
Combinatorial Homology in a Perspective of Image Analysis
Authors: Grandis Marco 
Published: March 2019

Abstract
This is the sequel of a paper where we introduced an intrinsic ho-motopy theory and homotopy groups for simplicial complexes. We study here the relations of this homotopy theory with the well-known homology theory of simplicial complexes. Also, our investigation is aimed at applications in image analysis. A metric space 𝑋 representing an image, has a structure of simplicial complex at each resolution ε > 0, and the corresponding combinatorial homology groups
give information on the image. Combining the methods developed here with programs for automatic computation of combinatorial homology might open the way to realistic applications.
Üniversal adezivlerin vital beyazlatma yapılmış dişlerde bağlanma dayanımına etkisi
Authors: UÇAR Ebru Nur , ARSLAN Soley , DEMİRBUĞA Sezer , ÇAYABATMAZ Muhammed 
Published: March 2019

Amaç: Bu çalışmanın amacı
hidrojen peroksit içerikli vital beyazlatma uygulamasını takiben uygulanan
universal bir adeziv sistemin mineye mikro makaslama bağlanma dayanımı
kuvvetinin değerlendirilmesidir.Gereç ve Yöntemler:Bu amaçla, çekilmiş 60
mandibular premolar dişin düzleştirilmiş labiyal mine yüzeylerine % 40 hidrojen
peroksit içeren jel (Opalescence Boost) uygulanmıştır. Yapay tükürük içerisinde
iki haftalık bekleme süresini takiben dişler uygulanacak adeziv sistemlere göre
4 gruba ayrılmıştır (n=15); Single Bond Universal (etch&amp;rinse modunda) (SBUE)
(3M ESPE), Single Bond Universal (self-etch modunda) (SBUS), One Step (OS)
(Bisco), Adper Easy One (AEO) (3M ESPE).
Mine yüzeylerine adeziv sistemlerin uygulanmasını takiben tygon tüpler ile
kompozit rezin materyal yerleştirilmiş ve mikro makaslama bağlanma dayanımı
testi gerçekleştirilmiştir. Kopma yüzeyi ve kırılma tipleri SEM ile
incelenmiştir. Bulgular: SBUE hem kendi kontrol
grubuna oranla (SBUS) hem de diğer tüm gruplara göre istatistiksel olarak
anlamlı ölçüde yüksek bağlanma değerleri sunmuştur (p&lt;0.05). Bunu sırasıyla
OS, SBUS ve AEO grupları takip etmiştir. Sonuçlar: Hidrojen peroksit ile
vital beyazlatma işlemi sonrasında uygulanan üniversal adeziv etch&amp;rinse
sistemde uygulandığında daha yüksek mikro makaslama bağlanma dayanımı gösterir.Anahtar Kelimeler: Bağlanma dayanımı,
beyazlatma, etch&amp;rinse, üniversal adeziv
Monostotik Mandibular Fibröz Displazi: Olgu Sunumu
Authors: Çebi Ahmet Taylan , İla Kadri , Yılmaz Nihat 
Published: March 2019

Fibröz
displazi sıklıkla çocuk yaşlarda ve ergenlerde görülen; kemiğin gelişimsel,
yavaş büyüyen, fibroosseöz benign bir lezyonudur. Fibröz displazi bir ya da
birden çok kemiği etkiliyebilir. Fibröz
displazi klinik olarak ikiye ayrılır ve bunlar monostotik ve poliostotik fibröz
displazi olarak adlandırılırlar. Radyografik görüntüsünde, displazik lezyon
içindeki artan kemik oluşumunda birlikte 'buzlu cam' veya 'portakal kabuğu'
görüntüsünü andırmaktadır. Bu olgu sunumunda klinik, radyografik ve
histopatolojik incelemelerle tanısı koyulmuş fibröz displazi olgusu sunulmuştur.
Üst Çenede Çift Taraflı Gömülü Köpek Dişi-Birinci Küçük Azı Transpozisyonu ve Yan Keser Diş Eksikliğinin Multidisipliner Tedavisi Multidisciplinary Treatment of Bilateral Maxillary Impacted Canine- First Premolar Transposition and Lateral Incisor Agenesis
Authors: ULUSOY MUTLUOL Esra 
Published: March 2019

Ön bölgedeki diş eksiklikleri ve transpozisyonlar
stratejik konumlarından dolayı ciddi estetik ve fonksiyonel problemlere neden
olmaktadır. Estetik ve fonksiyonel başarının sağlanması ancak doğru tanı ve
uygulamalara bağlıdır. Bu olgu raporunda, üst çenede çift taraflı gömülü köpek
dişi birinci küçük azı dişi transpozisyonu ve yan keser diş eksikliği olan 13
yaşında bir bayan hasta anlatılmaktadır. Ortodontik tedavi planı birinci küçük
azı dişlerinin yan keser diş alanına taşınması, gömülü dişlerin sürdürülmesi ve
alt birinci küçük azı dişlerinin çekilmesidir. Gömülü dişler 1 yıl 4 ayda
sürdürülmüştür ve daha sonrasında birinci küçük azı dişleri yan keser dişlere
benzetilecek şekilde aşındırılıp restoratif tedavi yapılmıştır. Ortodontik
tedavi 2 yıl 8 ayda tamamlanmıştır.

Anahtar
Kelimeler: Diş eksikliği, transpozisyon, ortodonti

Agenesis and tooth transposition in the anterior
region cause serious esthetic and functional problems
due to
their strategic location. The esthetic and functional success depends on the
correct diagnosis and clinical procedures.
In this case report 13-year-old female with bilateral maxillary impacted
canine-first premolar transposition and lateral incisor agenesis. Orthodontic
treatment plan involved orthodontic traction of bilaterally impacted canine
after providing adequate space, orthodontic movement of first premolar tooth
into lateral incisor sides and extraction lower bilateral first premolar. The
impacted tooth were erupted and aligned in 1 year and four months and then the
first premolars were stripped in order to mimic a lateral incisor. Orthodontic
treatment was completed in 2 years and 8 months.

Keywords: Agenesis,
transposition, orthodontics
Mortalidad por enfermedades digestivas no neoplásicas en la población adulta del Perú, 2010 – 2015
Authors: Castillo-Contreras Ofelia , Flores-Flores Claudio 
Published: March 2019

Introducción. Las enfermedades digestivas (ED) no neoplásicas son causas importantes de consulta médica y hospitalización. Objetivo. Determinar la mortalidad por ED no neoplásicas en la población adulta del Perú entre 2010 y 2015. Métodos. Análisis secundario del registro de defunciones por ED no neoplásicas en la población mayor de 18 años entre los años 2010 y 2015 de la Oficina General de Estadística e Informática del Ministerio de Salud del Perú. La población para el mismo periodo se obtuvo del Instituto Nacional de Estadística e Informática. Se calcularon las tasas de mortalidad estandarizada (TME x 100 000 personasaño). Resultados. Durante el período 2010-2015 se registraron 39 889 muertes por ED no neoplásicas. Las TME más altas fueron para el grupo de las enfermedades del hígado (12,2 x 100 000 personas-años), siendo la fibrosis y cirrosis del hígado la de mayor mortalidad (9,1). La pancreatitis aguda (1,0) tuvo mayor TME que la úlcera gástrica (0,7). Las TME, según las regiones del Perú, fueron altas por fibrosis y cirrosis del hígado en Piura (16,3), Lambayeque (14,6) y La Libertad (14,4); por colelitiasis (1,1) y colecistitis aguda (1,7), en Puno; por pancreatitis aguda (2,2), en Tacna; y por úlcera gástrica fue mayor en Huancavelica (3,6) y Huánuco (2,3). Conclusiones. La fibrosis y cirrosis del hígado fue la ED no neoplásica con mayor tasa de mortalidad en la población adulta del Perú, principalmente en la costa norte del país.
Guía de práctica clínica basada en evidencias para el tratamiento de depresión en adultos en un hospital especializado en salud mental. Lima, Perú
Authors: Vargas Cajahuanca Gisella , Gallegos Cazorla Carolina , Salgado Valenzuela Carlos , Salazar de la Cruz Miriam , Huamán Sánchez Karen , Bonilla Untiveros Catherine , Reyes Puma Nora , Caballero Ñopo Patricia 
Published: March 2019

Introducción. La depresión es un trastorno mental que en su forma más grave puede terminar en el suicidio. Objetivo. La presente guía de práctica clínica basada en evidencias (GPC-BE) brinda recomendaciones para el tratamiento farmacológico y psicoterapéutico de la depresión en adultos. Métodos. Se elaboró una GPC-BE adaptada mediante un proceso sistemático, riguroso y transparente con un grupo elaborador conformado por metodólogos y psiquiatras expertos en el manejo de la enfermedad. La guía cuenta con siete preguntas clínicas y 10 recomendaciones; se realizó la búsqueda y preselección de GPC que respondan al alcance y objetivos planteados, las mismas que fueron evaluadas mediante el instrumento “Appraisal of Guidelines for Research and Evaluation II” (AGREE-II), seleccionándose la guía de mejor calidad metodológica para su adaptación. La búsqueda sistemática de evidencias para responder las preguntas clínicas se realizó en múltiples bases de datos: MEDLINE/PubMed, EMBASE/Ovid, Cochrane Library, LILACS y SciELO. Las evidencias fueron seleccionadas y analizadas críticamente por pares clínicos y metodológicos, las recomendaciones fueron elaboradas mediante la metodología Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Resultados. Con la participación de un panel de expertos clínicos de diferentes hospitales de referencia en el manejo de depresión, se elaboraron 10 recomendaciones dirigidas al inicio del tratamiento farmacológico y psicoterapéutico, la terapia combinada, psicoterapia individual-grupal, y eventos adversos de la farmacoterapia en los pacientes adultos con depresión. Conclusiones. El presente artículo es un resumen de la guía de práctica clínica basada en evidencias para el tratamiento de depresión en adultos para un hospital público peruano especializado en salud mental.
An extension of $z$-ideals and $z^\circ$-ideals
Authors: ALİABAD Ali Rezaei , BADİE Mehdi , NAZARİ Sajad 
Published: March 2019

Let $R$ be a commutative ring, $Y\subseteq Spec(R)$ and $ h_Y(S)=\{P\in Y:S\subseteq P \}$, for every $S\subseteq R$. An ideal $I$ is said to be an $\mathcal{H}_Y$-ideal whenever it follows from $h_Y(a)\subseteq h_Y(b)$ and $a\in I$ that $b\in I$. A strong $\mathcal{H}_Y$-ideal is defined in the same way by replacing an arbitrary finite set $F$ instead of the element $a$. In this paper these two classes of ideals (which are based on the spectrum of the ring $R$ and are a generalization of the well-known concepts semiprime ideal, z-ideal, $z^{\circ}$-ideal (d-ideal), sz-ideal and $sz^{\circ}$-ideal ($\xi$-ideal)) are studied. We show that the most important results about these concepts, Zariski topology", annihilator" and etc can be extended in such a way that the corresponding consequences seems to be trivial and useless. This comprehensive look helps to recognize the resemblances and differences of known concepts better.
Acentralizers of Abelian groups of rank 2
Authors: MOZAFAR Zahar , TAERİ Bijan 
Published: March 2019

Let $G$ be a group. The Acentralizer of an automorphism $\alpha$ of $G$, is the subgroup of fixed points of $\alpha$, i.e., $C_G(\alpha)= \{g\in G \mid \alpha(g)=g\}$. We show that if $G$ is a finite Abelian $p$-group of rank $2$, where $p$ is an odd prime, then the number of Acentralizers of $G$ is exactly the number of subgroups of $G$. More precisely, we show that for each subgroup $U$ of $G$, there exists an automorphism $\alpha$ of $G$ such that $C_G(\alpha)=U$. Also we find the Acentralizers of infinite two-generator Abelian groups.
EXPERIENCIAS E IMPACTO SOCIAL EN LA APLICACIÓN DE INGENIERÍA DE REQUISITOS EN EL DESARROLLO DE UNA PLATAFORMA INTELIGENTE
Authors: Maquera Gladys , Mariaca Jesús , Mendoza Óscar , Condori Fernandez Nelly 
Published: March 2019

El turismo rural comunitario (TRC) es una actividad que contribuye, desde las zonas rurales, al desarrollo económico-social y sostenible de un país. En este trabajo de investigación se tuvo como objetivo desarrollar una Plataforma Inteligente (PI) que satisfaga las necesidades de los distintos actores del TRC. Se presenta la experiencia centrada en Ingeniería de requerimientos, pasando por distintas iteraciones, donde se realizó el análisis FODA, uso de la programación extrema, cumplimiento de la ISO 25010, entre otros. La identificación precisa de los requerimientos fue determinante para que la implementación y usabilidad de la plataforma tenga un impacto social en los actores directos.