bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review of oncological emergencies in small animal patients
Authors: Tumielewicz Katrina L. , Hudak Danielle , Kim Jennifer , Hunley David W. , Murphy Lisa A. 
Published: March 2019

AbstractOncological emergencies can occur at any time during the course of a malignancy and need to be recognized promptly to maximize successful outcomes. Emergencies are characterized as chemotherapy‐induced, paraneoplastic syndromes, or directly related to the neoplasm. Prompt identification with treatment of these emergencies can prolong survival and improve quality of life, even in the setting of terminal illness. This review aims to educate the reader on the pathophysiology, clinical presentation and treatment of some of these emergencies, and to review the current veterinary literature to help educate veterinarians in primary and tertiary facilities to know how to diagnose and treat these serious conditions.
On the global well‐posedness of the tropical climate model
Authors: Li Jinlu , Zhai Xiaoping , Yin Zhaoyang 
Published: March 2019

AbstractIn this paper, we mainly study the Cauchy problem of the tropical climate model in negative‐order Besov spaces. By using the iterative scheme and compactness argument, we first establish the local well‐posedness of the model and then we can extend this local solution to be global if the initial data is sufficient small.
Stabilization and asymptotic behavior of non local damped wave equations
Authors: Nicaise Serge 
Published: March 2019

AbstractMotivated by different models of damped nanorods and nanoplates, we introduce an abstract framework of non local damped second order evolution equations. We analyze the stability and the asymptotic behavior of such evolution equations. We then illustrate our general results by some stability results for some models of damped nanorods and nanoplates.
The holographic non-abelian vortex
Authors: Tallarita Gianni , Auzzi Roberto , Peterson Adam 
Published: March 2019

AbstractWe study a fully back-reacted non-abelian vortex solution in an extension of the holographic superconductor setup. The thermodynamic properties of the vortex are computed. We show that, in some regime of parameters, the non-abelian vortex solution has a lower free energy than a competing abelian vortex solution. The solution is dual to a finite-temperature perturbed conformal field theory with a topological defect, on which operators related to the Goldstone modes of a spontaneously broken symmetry are localized. We compute numerically the retarded Green function of these operators and we find, in the classical approximation in the bulk, a gaplessℂℙ1excitation on the vortex world line.
Has your wifi left you wide open to cybercrime?
Authors: Schofield Greig 
Published: March 2019

Picture your own home. You've spent significant budget ensuring your property is physically secure, only to discover that criminals have been silently robbing you, without so much as setting foot on your front porch. You believed you'd created a fortress but didn't notice the hole in the wall that left you vulnerable to criminals. It's every single homeowner's worst nightmare. However, it's also a very real metaphor for many businesses in the UK who, despite becoming more vulnerable, have left the door to cybercrime unknowingly ajar. IT security is now a corporate priority and businesses are investing significant funds into sophisticated firewalls that enable their systems to become effectively inaccessible. But many of those businesses fail to notice the growing hole in their IT defences that leaves both the business and its workers exposed – their wifi network. Defective wifi practice, along with an insufficient understanding of the obvious signs of cyberthreats, can unwittingly provide cyber criminals with surreptitious access to sensitive information, explains Greig Schofield of Netmetix.
A leader indeed is a leader in deed: The relationship of ethical leadership, person–organization fit, organizational trust, and extra-role service behavior
Authors: Kerse Gökhan 
Published: March 2019

AbstractIn this study, the effect of ethical leadership on extra-role service behavior, and the role of person–organization fit and organizational trust on this effect were examined. A multi-level research model was established in the research and hypotheses were tested within this model. The data of this research study were obtained from 205 workers of two hospitals (public and private), in a certain province in Turkey. The obtained findings demonstrated that ethical leadership strengthened the trust in the organization both directly and over person–organization fit. Moreover, based on the findings, it was determined that ethical leadership increased extra-role service behavior by means of organizational trust. The theoretical and practical implications of all of the findings were discussed and evaluated in the context of national culture.
The association between intake of dietary lycopene and other carotenoids and gestational diabetes mellitus risk during mid-trimester: a cross-sectional study
Authors: Gao Qin , Zhong Chunrong , Zhou Xuezhen , Chen Renjuan , Xiong Ting , Hong Miao , Li Qian , Kong Man , Han Weizhen , Sun Guoqiang , Yang Xuefeng , Yang Nianhong , Hao Liping 
Published: March 2019

AbstractThis study aimed to determine whether increased carotenoids intake was associated with reduced risk of gestational diabetes mellitus (GDM). We performed a cross-sectional analysis using data from Tongji Maternal and Child Health Cohort study. The dietary carotenoids intake of 1978 pregnant women was assessed using a researcher-administered FFQ before undertaking an oral glucose tolerance test at 24–28 weeks. Multivariate logistic and linear regression analyses were used to obtain the effect estimates. Participants in the highest quartile of lycopene intake showed a lower risk of GDM (OR 0·50; 95 % CI 0·29, 0·86;Pfor trend= 0·007) compared with those in the lowest quartile; each 1 mg increase in lycopene consumption was associated with a 5 % (95 % CI 0·91, 0·99;Pfor trend= 0·020) decrease in GDM risk. No significant association was found between α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin intake and GDM risk. Multiple linear regression analysis suggested an inverse association between lycopene intake and fasting blood glucose (FBG) (Pfor trend< 0·001); each 1 mg increase in lycopene intake was associated with 0·005 (95 % CI 0·002, 0·007;Pfor trend< 0·001) mmol/l decrease in FBG. Interaction analysis indicated consistent effect on each age or pre-BMI subgroup; however, a stronger protective effect of lycopene intake against GDM was observed among primigravid women (OR 0·20; 95 % CI 0·07, 0·55 in the highestv. the lowest quartile of intake;Pfor interaction= 0·036). In conclusion, dietary lycopene intake was mainly assumed via reducing FBG to decrease GDM risk, and the protection was relatively increased among primigravid women.
A NOTE ON THE ‘NEW APULEIUS’ (3.20 STOVER, P. 100)
Authors: Shumilin Mikhail 
Published: March 2019

Lines 3.20–2 of the text published by Justin Stover as Apuleius’ De Platone 3 are printed by him as follows:
improbat deinde eos qui negantis homines in seruitute habeant aut qui omnino eiusdem ciuitatis nationem belli iure diruant aut qui hostium spolia deorum aedibus adfigant.He [sc. Plato] then rebukes those who hold people in slavery against their will, or else who destroy utterly the people of that same city by right of war, or who hang the spoils of enemies on the shrines of the gods. (transl. J. Stover)
Nanoindentation Properties and Finite Element Analysis of the Rostrum of Cyrtotrachelus buqueti Guer (Coleoptera: Curculionidae)
Authors: Li Longhai , Guo Ce , Xu Shun , Ma Yaopeng , Yu Zhiwei 
Published: March 2019

AbstractThis work focuses on the application of nanoindentation measurements and the finite element method for analyzing the mechanical properties of the rostrum of the outstanding driller Cyrtotrachelus buqueti Guer. Nanoindentation tests were carried out to measure the Young's modulus and hardness of the rostrum, with the results for the “dry” samples being 13.886 ± 0.75 and 0.368 ± 0.0445 GPa, respectively. The values for the “fresh” samples showed no clear difference from those of the “dry” ones. Moreover, field observation was conducted to determine the motion behaviors of the rostrum on the weevil. Micro-computed tomography technology was employed to obtain structural information about the rostrum, using 9 µm slices. A real three-dimensional model of the rostrum was created using the MIMICS application. Finally, the mechanical properties of the rostrum were determined by finite element analysis. It was concluded that the rostrum provides an ideal biological template for the design of biocomposite materials and lightweight tube-shaped structures. The properties determined in this study can potentially be applied in different fields, such as in the design of automotive hybrid transmission shafts, helicopter tail drive shafts, robotic arms, and other sandwich structures in aerospace engineering.
STANDARD BAYES LOGIC IS NOT FINITELY AXIOMATIZABLE
Authors: GYENIS ZALÁN 
Published: March 2019

AbstractIn the article [2] a hierarchy of modal logics has been defined to capture the logical features of Bayesian belief revision. Elements in that hierarchy were distinguished by the cardinality of the set of elementary propositions. By linking the modal logics in the hierarchy to the modal logics of Medvedev frames it has been shown that the modal logic of Bayesian belief revision determined by probabilities on a finite set of elementary propositions is not finitely axiomatizable. However, the infinite case remained open. In this article we prove that the modal logic of Bayesian belief revision determined by standard Borel spaces (these cover probability spaces that occur in most of the applications) is also not finitely axiomatizable.
A linuron-free weed management strategy for carrots
Authors: de Boer Tessa , Smith Peter , Chandler Kevin , Nurse Robert , Obeid Kristen , Swanton Clarence 
Published: March 2019

AbstractThe development of a linuron-free weed management strategy for carrot production is essential as a result of the herbicide reevaluation programs launched by the Pest Management Regulatory Agency in Canada for herbicides registered before 1995 and the discovery of linuron-resistant pigweed species in Ontario. Field trials were conducted in one of Ontario’s main carrot-growing regions on high organic soils in 2016 and 2017. Pigweed species seedlings were effectively controlled with PRE treatments of prometryn, pendimethalin, S-metolachlor, or glufosinate. POST treatments of pyroxasulfone and metribuzin followed by predetermined biologically effective dose (≥90% control of pigweed seedlings) of acifluorfen, oxyfluorfen, fluthiacet-methyl, and fomesafen achieved excellent crop selectivity and commercially acceptable pigweed species seedling control under field conditions. Carfentrazone-ethyl or fomesafen applied PRE severely reduced seedling emergence and yield in the wet growing season of 2017. This study demonstrated clearly that an alternative linuron-free strategy can be developed for carrots. The strategy of exploring the potential to use the biologically effective dose of selected herbicides to achieve crop selectivity and control of pigweed species seedlings was verified.
Meteorological Source Variability in Atmospheric Gravity Wave Parameters Derived From a Tropical Infrasound Station
Authors: Marlton G. J. , Charlton‐Perez A. J. , Harrison R. G. , Blanc E. , Evers L. , Le‐Pichon A. , Smets P. S. M. 
Published: March 2019

AbstractGravity waves are an important part of the momentum budget of the atmosphere. Despite this, parameterizations of gravity wave spectra in atmospheric models are poorly constrained. Gravity waves are formed by jet streams, flow over topography, and convection, all of which produce pressure perturbations as they propagate over the Earth's surface, detectable by microbarometer arrays used for sensing infrasound. In this study, observations of gravity waves between 2007 and 2011 at an infrasound station in the Ivory Coast, West Africa, are combined with meteorological data to calculate parameters such as intrinsic phase speed and wavenumber. Through spectral analysis, the seasonal and daily variations in all gravity wave parameters are examined. The gravity wave back azimuth varies with the migration of the Intertropical Convergence Zone, a region of intense convection, supporting previous studies. Daily variations in gravity wave arrivals at the station can be linked to two distinct convective cycles over the land and ocean. This was achieved by combining the gravity wave parameters with lightning strikes detected by the Met Office's Arrival Time Difference lightning detection system. Noise generated by turbulence in the middle of the day was found to attenuate smaller pressure amplitude gravity waves, artificially amplifying the daily variations in some gravity wave parameters. Detection of daily and seasonal variations in gravity wave parameters has the potential be used to improve the representation of gravity wave spectra in atmospheric models.
Snowmelt‐Triggered Earthquake Swarms at the Margin of Long Valley Caldera, California
Authors: Montgomery‐Brown E. K. , Shelly D. R. , Hsieh P. A. 
Published: March 2019

AbstractFluids are well known to influence earthquakes, yet rarely are earthquakes convincingly linked to precipitation. Weak modulation or limited data often leads to ambiguous interpretations. In contrast, here we find that shallow seismicity in the Sierra Nevada range near Long Valley Caldera is strongly modulated by snowmelt. Over 33 years, shallow seismicity rates were ~37 times higher during very wet periods versus very dry periods. Relative earthquake relocations from a swarm in 2017 reveal downward migration from ~1‐ to 3‐km depth along a steeply inclined plane. Steeply dipping strata may provide high‐permeability pathways and faulting plane. Here we combine the correlated seismicity and hydrologic time series with the propagation observed in the relatively relocated earthquakes. From this combined evidence, we infer that pressure diffusion from groundwater recharge dramatically accelerated shallow seismicity rates, causing seismic swarms unrelated to volcanic processes.
Deacetylation of CHK2 by SIRT1 protects cells from oxidative stress-dependent DNA damage response
Authors: Kwon Jiyun , Lee Suhee , Kim Yong-Nyun , Lee In Hye 
Published: March 2019

AbstractGrowing evidence indicates that metabolic signaling pathways are interconnected to DNA damage response (DDR). However, factors that link metabolism to DDR remain incompletely understood. SIRT1, an NAD+-dependent deacetylase that regulates metabolism and aging, has been shown to protect cells from DDR. Here, we demonstrate that SIRT1 protects cells from oxidative stress-dependent DDR by binding and deacetylating checkpoint kinase 2 (CHK2). We first showed that essential proteins in DDR were hyperacetylated in Sirt1-deficient cells and that among them, the level of acetylated CHK2 was highly increased. We found that Sirt1 formed molecular complexes with CHK2, BRCA1/BRCA2-associated helicase 1 (BACH1), tumor suppressor p53-binding protein 1 (53BP1), and H2AX, all of which are key factors in response to DNA damage. We then demonstrated that CHK2 was normally inhibited by SIRT1 via deacetylation but dissociated with SIRT1 under oxidative stress conditions. This led to acetylation and activation of CHK2, which increased cell death under oxidative stress conditions. Our data also indicated that SIRT1 deacetylated the K235 and K249 residues of CHK2, whose acetylation increased cell death in response to oxidative stress. Thus, SIRT1, a metabolic sensor, protects cells from oxidative stress-dependent DDR by the deacetylation of CHK2. Our findings suggest a crucial function of SIRT1 in inhibiting CHK2 as a potential therapeutic target for cancer treatment.
A service evaluation of the “Open Wide and Step Inside” school oral health programme
Authors: Witton Robert , Smith Wendy 
Published: March 2019

Abstract
Introduction
To present a service evaluation of the “Open Wide and Step Inside” oral health programme delivered in Plymouth, UK.

Aim
To develop an oral health programme supporting Key Stage One of the National Curriculum for delivery to children aged 4–6 years in targeted schools.

Methods
The programme was designed and developed in partnership with stakeholders from a range of sectors using a community engagement approach. The programme has been delivered in schools in targeted areas of the city since 2014/15. Outcome (participation of schools and children) and process evaluations were carried out using a range of methods to collect feedback from children, teachers and parents.

Results
School adoption and engagement in the programme has been high exceeding the targets set for implementation. So far over 4000 children have participated in the programme and schools have welcomed support in delivering oral health as part of the national curriculum.

Conclusion
A community engagement approach can be highly valuable in developing oral health programmes that meet community needs through collaborative design and a participatory approach.
Applicability of Demirjian’s method for dental age estimation in a group of Egyptian children
Authors: Moness Ali Amro M. , Ahmed Wael H. , Khattab Nagwa M. 
Published: March 2019

Abstract
Aims
The aims of this study were to evaluate the applicability of Demirjian’s method for dental age assessment in a group of Egyptian children in Minia city and to develop an age predictive equation suitable for the studied group.

Subjects and methods
In this retrospective, blind, cross-sectional study, 160 dental panoramic radiographs (DPTs) were selected from 420 DPTs from healthy children aged between three and 10 years old from the archived medical files of patients attending Minia University Dental Hospital (MUDH) and evaluated to estimate dental ages.

Results
Age was overestimated for almost all of the studied subjects with an accuracy range from 0.18 to 1.19 years for males and from 0.08 to 0.87 years for females, with the exception of two age subgroups (9–10-year-old males and 10–11-year-old females, for which the mean difference values were −0.06 and −0.008 years, respectively). A Logistic regression was used to generate a suggested formula for dental age estimation.

Conclusions
Demirjian’s method may be unsuitable for Egyptian children living in Minia city. Development of a predication equation and the introduction of adaptable conversion tables to transform the maturity score into a dental age for Egyptian children may be suitable alternatives. The validity of the newly developed prediction equation must be tested among all Egyptian children.
Interactions of an Emerging Fungal Pathogen Scedosporium aurantiacum with Human Lung Epithelial Cells
Authors: Kaur Jashanpreet , Kautto Liisa , Penesyan Anahit , Meyer Wieland , Elbourne Liam D. H. , Paulsen Ian T. , Nevalainen Helena 
Published: March 2019

AbstractScedosporium fungi are found in various natural and host-associated environments, including the lungs of cystic fibrosis patients. However, their role in infection development remains underexplored. Here the attachment of conidia of a virulent S. aurantiacum strain WM 06.482 onto the human lung epithelial A549 cells in vitro was visualized using microscopy to examine the initial steps of infection. We showed that 75–80% of fungal conidia were bound to the A549 cells within four hours of co-incubation, and started to produce germ tubes. The germinating conidia seemed to invade the cells through the intercellular space, no intracellular uptake of fungal conidia by the airway epithelial cells after conidial attachment. Transcriptomic analysis of the A549 cells revealed that the up-regulated genes were mainly associated with cell repair and inflammatory processes indicating a protective response against S. aurantiacum infection. Network analysis of the differentially expressed genes showed activation of the innate immune system (NF-kB pathway) leading to the release of pro-inflammatory cytokines. We believe this is the first report showing the transcriptomic response of human alveolar epithelial cells exposed to S. aurantiacum conidia paving a way for better understanding of the mechanism of the infection process.
A new transitional therizinosaurian theropod from the Early Cretaceous Jehol Biota of China
Authors: Yao Xi , Liao Chun-Chi , Sullivan Corwin , Xu Xing 
Published: March 2019

AbstractTherizinosaurian theropods evolved many highly specialized osteological features in association with their bulky proportions, which were unusual in the context of the generally gracile Theropoda. Here we report a new therizinosaur,Lingyuanosaurus sihedangensisgen. et sp. nov., based on a specimen recovered from the Lower Cretaceous Jehol Group of Lingyuan, Liaoning Province, China, which displays a combination of plesiomorphic and derived features. Most notably, the specimen is characterized by posterior dorsal vertebrae with a complex and unusual laminar structure; an ilium with a highly dorsoventrally expanded preacetabular process showing only slight lateral flaring of the ventral margin, a strongly anterodorsally inclined iliac blade, a small postacetabular process with a strongly concave dorsal margin, and a relatively robust pubic peduncle with a posteroventrally facing distal articular surface; a straight and robust femur with a small lesser trochanter; and a tibia that is longer than the femur. Phylogenetic analysis placesLingyuanosaurusin an intermediate position within Therizinosauria, i.e., between the early-branching therizinosaurs such asFalcarius,Jianchangosaurus, andBeipiaosaurusand the late-branching ones such asAlxasaurusandTherizinosaurus. This new therizinosaur sheds additional light on the evolution of major therizinosaurian characteristics, including particularly the distinctive pelvic girdle and hindlimb morphology seen in this group.
Important evidence of constant low CO2 windows and impacts on the non-closure of the greenhouse effect
Authors: Zhao Jing , Li Guoqing , Cui Weihong , Cao Qianqian , Zhang Haoping 
Published: March 2019

AbstractThe CO2 distribution in the atmosphere remains unclear for the complexity of the long-range vertical transport process and other influencing factors. In this work, regression analysis was used to verify the accuracy of CO2 concentrations datasets. Geostatistical analyses were used to investigate the spatiotemporal distributions of CO2 at 7 levels from near the surface to the mid-troposphere (0~5 km). Spatial correlation and time series analyses were used to further determine the diffusion characteristics of the CO2 concentration based on the horizontal wind (NCEP R2), which is one of the main driving factors. The results showed that the horizontal, not vertical, diffusion of CO2 becomes increasingly more prominent with the decrease in atmospheric pressure to the mid-troposphere, whereas many regions, such as the Rocky Mountains and Qinghai-Tibet Plateau, have constant low values throughout the year due to the influence of high topography (up to 10.756 ppmv lower than that near the surface). These areas form low CO2 concentration ‘windows’ keeping letting thermal infrared energy out into space. This study is the first to question the existing view of the closure of the ‘greenhouse effect’. Future research studies should more precisely determine the closure threshold and the uncertainties about the surface fluxes.