bluuebunny/crossref_metadata_2025_split huggingface dataset:
The prediction of pregnancy induced hypertension from umbilical and uterine Doppler flow study
Authors: Gadhavi Vijay N. , Gadhavi Mansi K. , Pandya Manish 
Published: January 2019

Background: Hypertensive disorder along with hemorrhage and infection contribute greatly to maternal mortality and morbidity. Pregnancy induced hypertension remains among the most significant and intriguing unsolved problems in obstetrics.Methods: In this prospective analytical study investigations and color doppler findings 0f umbilical artery PI, RI and end diastolic flow in same, uterine PI, RI and persistent diastolic notch in uterine artery recorded. Total 100 Cases of PIH between 20-36 weeks of gestation in 2 years with B.P ≥ 140/90 mm hg and protienuria ≥ 1+ were observed.Results: In this study, out of 100 cases, there were 58 cases of mild PIH (58%) and 42 cases of severe PIH (42%). Umbilical artery PI was elevated in 43(43.0%) patients and was normal in 57(57.0%) patients. Umbilical artery RI was more than and equal to 0.7 in 77 patients (77%) and was below of 0.7 in 23 (23%) pa-tients.9(9.0%) fetuses showed absence and 14 (14.0%) fetus had reversal and 46 (46.0%) had reduced end diastolic umbilical artery flow with total 69 out of 100 fetuses having abnormal waveforms.65 (65%) mothers had an elevated uterine artery PI and 35(35%) patients had normal uterine artery PI. in observation 69 (69%) patients were having RI more than 0.6, while 31 (31%) were having less than 0.6 out of 100 patients. In this study, 65 (65.0%) women were having persistent diastolic notch.Conclusions: This study was to evaluate arterial flow velocities as a predictor of impending pregnancy induced hypertension with raised RI and PI along with umbilical ab-sent or reverse end diastolic flow velocities and elevated RI and PI in the presence of a diastolic notch are considered as abnormal uterine doppler findings doppler finding with unfavorable outcome.
Clinical presentation and outcome of ectopic pregnancies in a tertiary care rural hospital
Authors: Verma Indu , Priya Punya , Chugh Charvi , Kaur Harsharan , Sood Dinesh 
Published: January 2019

Background: Ectopic pregnancy is the commonest cause of the maternal morbidity and mortality in the first trimester of the pregnancy. The aim of this study was to see the clinical presentation, associated risk factors, mode of treatment and outcome.Methods: Retrospective study conducted in a tertiary care rural hospital. Women with diagnosis of ectopic pregnancy admitted between August 2016 to September 2018 were studied. Medical record files were scrutinized to get the details. Data was analyzed using Microsoft Office Excel (version 2007). Numerical data were subjected to descriptive analysis, with mean±standard deviation (SD) and categorical data as frequency and percentage.Results: Forty cases of ectopic pregnancy were included who were unbooked, non-smokers, married and belonged to rural areas. Eighty percent were in the age group of 20 to 30 years. Maximum were gravida 3 or 4 with commonest presentation was pain, site was tubal. Laparotomy was done in 95% of women salpingectomy was the commonest surgical procedure done in 32 (80%) women. Salpingoophrectomy was done in one woman and lifesaving hysterectomy in 2 (5%) women for cervical and ruptured interstitial ectopic pregnancy one each. Blood transfusion was required in 28 (70%) women. No mortality was seen.Conclusions: Women of reproductive age group with pain abdomen and menstrual complaints, even without amenorrhoea, ectopic pregnancy should be ruled out. Treating reproductive tract infections / PID and offering contraceptives will decrease the incidence of ectopic pregnancy. Medical and paramedical staff should do the timely referral to higher centres.
Hereditary angioedema caused by C1-esterase inhibitor deficiency: a case report with literature-based analysis
Authors: Athar Sufia , Korichi Noureddine , Siam Yousra Shehada 
Published: January 2019

Hereditary angioedema (HAE) caused by C1-esterase inhibitor deficiency is an autosomal-dominant disease caused by a mutation in the C1-inhibitor gene. It is a rare disease that is often worsened during pregnancy and childbirth. HAE, though uncommon but if untreated it may lead to maternal death. The case report presents the successful management of a 24 years old, G2P1, with hereditary angioedema caused by C1-esterase inhibitor deficiency. This patient was managed with a multidisciplinary approach by an obstetrician, an immunologist, an anaesthesiologist and a pediatrician. She had an uneventful antenatal period, labor was induced. She had precipitate delivery and soon after delivery had a flare up of the disease. It was successfully managed with fresh frozen plasma and close observation.
Capillary haemangioma of fallopian tube: a rare but dangerous incidental finding
Authors: Yadav Shakti Kumar , Bhoj Mishika , Salhan Sudha , Sarin Namrata , Singh Sompal 
Published: January 2019

Haemangiomas are tumors of vascular origin. They are frequently observed in soft tissue and skin. Vascular tumors of female pelvic organs are extremely rare. Although, majority of these lesions are detected incidentally, they can mimic various benign and malignant lesions clinically and radiologically. Fallopian tube capillary haemangioma is very rare benign neoplasm. Only one case of capillary haemangioma of fallopian tube has been reported. A 44-year-old female with menorrhagia, underwent hysterectomy with bilateral salpingoopherectomy. Both the fallopian tubes were grossly unremarkable. Microscopic examination revealed a well circumscribed vascular neoplasm, consistent with capillary haemangioma, CD34 immunostaining highlighted the vascular endothelium. Although benign in nature, haemangioma of the fallopian tube can present with complications. Rupture of the haemangioma can be lethal when present with hemoperitoneum.
A retrospective study of mucocutaneous lesions of SLE patients and their systemic implications
Authors: Ponnurangam Rekha Gurunatham , Kannan Rajkumar , Nallu Kamalanathan , Chandrasekar Muthusubramanian 
Published: January 2019

<p class="abstract"><strong>Background:</strong> SLE is a systemic disease with multiorgan involvement occuring very rarely, if so, it has a very grave prognosis if not detected early. Our study enlightens about the evolution of mucocutaneous lesions which can serve as an eye opener for early detection of systemic involvement.</p><p class="abstract"><strong>Methods:</strong> A descriptive study was conducted in the Department of Dermatology at a tertiary care centre from May 2017 to April 2018 retrospectively. From 15 confirmed cases of SLE a critical retrospective analysis of symptom complex evolution was done and thus a clinical correlation of evolution of mucocutaneous lesions and systemic involvement was attempted.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of the fifteen patients in our study comprising various age groups (4-51 years), mean age group was 29.76 years. 14 (93%) were female patients and 1 (6.6%) male patient. Oral ulcerations, Non-scarring alopecia and vasculitic lesions were predominant (3 patients-80%) followed by photosensitivity and cheilitis (9 patients- 60%). Systemic involvement was present in 9 (60%), out of which one (6%) patient had lupus nephritis and 3 patients (20%) had CNS lupus, 2 (13%) had chronic unilateral scleritis, 2 (13%) had interstitial lung disease, one (6%) had coronary heart disease. Mucocutaneous lesions preceded the systemic involvement in 88.8% of cases, with mean duration being 3 years (4 months – 10 years).</p><p class="abstract"><strong>Conclusions:</strong> Mucocutaneous lesions could serve as an eye opener for diagnosis of SLE, which is always a diagnosis made out of high degree of suspicion apart from certain mucocutaneous lesions serving as an ominous sign of system involvement in SLE.</p><p class="abstract"> </p>
KURAL BAZLI MUHASEBEDEN İLKE BAZLI MUHASEBEYE GEÇİŞİN İŞLETMELER AÇISINDAN STRATEJİK ÖNEMİ VE MUHASEBECİLERİN GÖRÜŞLERİ
Authors: YÜREKLİ Emin , SUSMUŞ Türker 
Published: January 2019

Küreselleşme
ülkeleri birbirini oldukça büyük bir hızla yaklaştırmakta ve bu durum finansal
piyasaları daha etkin ve birbirine daha
bağımlı hale getirdiği gözlenmekte ve bunun sonucu olarak da bir ülke veya
piyasada oluşan gelişmeler hızla diğer piyasaları da etkisi altına
almaktadır. Uluslararası Finansal
Raporlama Standartları ve bu standartların doğru ve ihtiyaca uygun bir şekilde
hazırlanıp sunulması ülkelerin küresel piyasalara uyumu ve entegresyonunda
oldukça önemli bir faktör olduğu bilinmektedir. UFRS ilke bazlı yaklaşım ile hazırlanmakta olup
bu nedenle daha az kural içermekte ve verdikleri genel ilkeler muhasebe meslek
mensupları tarafından yorumlanmaktadır. Bu durum ‘’mesleki yargı’’ olgusunu ön
plana çıkarmaktadır. Bu çalışmada Denizli ilinde faaliyet gösteren 7 tane
muhasebe meslek mensubuna odak grup çalışması uygulanmış, kural bazlı
muhasebeden ilke bazlı muhasebeye geçiş sürecinde muhasebe uygulamalarındaki
düşünce ve tercihleri ile ilgili bir takım sorular sorulmuş ve bu sorular
doğrultusunda elde etmiş olunan sonuçlar ayrıntılı bir şekilde açıklanmıştır.
Białka z rodziny Vps13 – od funkcji molekularnej do patogenezy chorób neurodegeneracyjnych
Authors: Kamińska Joanna , Kolakowski Damian 
Published: January 2019

Grupa białek Vps (ang. vacuolar protein sorting) zaangażowanych w transport do wakuoli została odkryta u drożdży Saccharomyces cerevisiae. Wśród białek Vps, jest rodzina Vps13, której przedstawiciele występują u organizmów z różnych grup systematycznych. U drożdży jest jedno białko Vps13, a u ludzi są cztery Vps13 – hVps13A-D. Są to białka duże, o charakterystycznej budowie domenowej. Mutacje w genach hVPS13 są powiązane z rzadkimi chorobami neurodegeneracyjnymi: pląsawicą-akantocytozą (hVPS13A), zespołem Cohena (hVPS13B/COH1), usposabiają do wczesnej choroby Parkinsona (hVPS13C) i prowadzą do ataksji/kurczowego porażenia kończyn (hVPS13D). Brak jasnych kryteriów diagnostycznych, szerokie spektrum niespecyficznych objawów powodują, że chorzy z neurodegeneracją są często źle diagnozowani i trudno jest określić liczbę pacjentów z mutacjami w genach hVPS13. Istotność białek z rodziny Vps13 dla zdrowia ludzi nakierowuje badania na poznanie ich funkcji molekularnej, która jest nieznana. Badania najczęściej prowadzone są w modelowych układach doświadczalnych, w których wywołano deficyt tych białek na drodze delecji lub wyciszenia ekspresji odpowiednich genów oraz na komórkach pochodzących od pacjentów. Opisano wiele zmian na poziomie komórkowym wywołanych brakiem białek Vps13, które dotyczą transportu komórkowego białek między cysternami aparatu Golgiego, błoną komórkową i endosomami, funkcjonowania mitochondriów i organizacji cytoszkieletu komórkowego, głównie aktynowego. Nie wiadomo jednakże, które zmiany są zmianami pierwotnymi, a które wtórnymi, kompensacyjnymi. Ostatnio badania na drożdżach pokazały Vps13, jako białko zlokalizowane w miejscach kontaktu błon, strukturach zapewniających wymianę metabolitów między różnymi organellami. Taka lokalizacja wydaje się być kluczowa dla funkcji Vps13. Na podstawie danych literaturowych proponujemy hipotezę o aktywnym udziale białek Vps13 w wymianie lipidów między błonami organelli w miejscach kontaktu błon, która tłumaczy większość fenotypów obserwowanych przy braku białka Vps13.
Penggunaan Media Pembelajaran Berbasis Audio Visual untuk Mata Pelajaran Konstruksi Bangunan
Authors: Rinaldi Anggi Aris , Daryati Daryati , Arthur Riyan 
Published: January 2019

Penelitian ini bertujuan untuk mengetahui peran media pembelajaran berbasis audio visual dalam meningkatkan hasil belajar siswa pada mata pelajaran konstruksi bangunan pada siswa kelas X TGB di SMK Negeri 56 Jakarta. Penelitian berlangsung dari November 2016 sampai dengan Januari 2017.
Metode yang digunakan dalam penelitian ini adalah metode eksperimen dengan bentuk penelitian nonequivalent control group design, yaitu penelitian yang dilakukan dalam satu populasi yang telah dibagi menjadi 2 kelompok. Kelompok kelas eksperimen diberikan perlakuan media audio visual sedangkan untuk kelas kontrol diberi perlakuan media konvensional, selain itu media pembelajaran yang dibuat divalidasi terlebih dahulu oleh beberapa ahli untuk mendapatkan kelayakan uji coba. Selanjutnya uji coba dilakukan pada peserta didik kelas X bidang keahlian Teknik Gambar Bangunan di SMK Negeri 56 Jakarta yang berjumlah 56 siswa. Analisis data menggunakan uji-t dua pihak sample independen melalui program aplikasi SPSS 23.
Hasil penelitian ini adalah: Berdasarkan nilai hasil belajar yang diperoleh, pada kelas eksperimen rata-rata nilai pre-test sebesar 55,79 dan terjadi peningkatan yang signifikan di hasil post-test dimana pada kelas eskperimen mendapatkan nilai rata-rata sebesar 89,54. Sedangkan untuk kelas kontrol rata-rata nilai pre-test yang diperoleh sebesar 62,39 dan pada saat post-test memperoleh nilai rata-rata sebesar 82,61. Kelas eksperimen memperoleh selisih rerata hasil belajar (pre-test & post-test) ilmu bahan bangunan sebesar 33,75 dan peningkatan yang terjadi sekitar 16,88%. Sedangkan pada kelas kontrol, selisih rerata hasil belajar (pre-test & post-test) ilmu bahan bangunan sebesar 20,22 dan peningkatan yang terjadi sebesar 10,11%. Maka hal tersebut mengindikasikan bahwa penggunaan media audio visual turut berperan dalam peningkatan hasil belajar siswa pada kelas eksperimen. Maka dapat disimpulkan bahwa terdapat pengaruh positif terhadap penggunaan media audio visual dalam meningkatkan hasil belajar dalam mata pelajaran konstruksi bangunan pada siswa kelas X TGB di SMK Negeri 56 Jakarta
Bridging Geomechanical and Geophysical Numerical Modeling: Evaluation of Seismic Efficiency and Rupture Velocity with Application to Estimating the Fractured Network Generated by Hydraulic Fracturing
Authors: Sheibani Farrokh , Hager Bradford 
Published: January 2019

Abstract
Microseismic monitoring is generally the most reliable method for estimating stimulated fractured volume. Receivers used in microseismic monitoring measure only seismic events. That limitation explains why only a small portion of the energy budget during hydraulic fracturing can be estimated by information obtained from microseismic monitoring.
We performed a series of numerical experiments to investigate the effects of rock mechanical properties and fracture friction characteristics on seismic efficiency and rupture velocity. We conducted numerical experiments using acoustic emission for saw-cut samples under triaxial loads and applied slip-weakening constitutive modeling for natural fractures to study how the Young's modulus and slip-weakening distance affect seismic efficiency and rupture velocity. Perhaps surprisingly, our results show that rocks with higher values of the Young's modulus have lower seismic efficiency generated from sliding on pre-existing natural fractures, while lower rigidity leads to higher seismic efficiency. These results do not contradict general beliefs about the effect of rigidity on fracability. More rigid rocks are more favorable for hydraulic fracturing and generate larger fracture networks; however, compared with less rigid rocks, fewer events would be detected seismically. The results also give insight into how to connect geomechanical numerical modeling of hydraulic fractures in naturally fractured reservoirs with microseismic data from the field and actual subsurface-generated fractured networks.
Power Law Correlation for Slickwater Proppant Dune Height
Authors: Alotaibi Msalli , Miskimins Jennifer 
Published: January 2019

Abstract
Poor proppant transport in slickwater is an industry challenge in the hydraulic fracturing of unconventional reservoirs. Part of this challenge is the difficulty in estimating the settled proppant dune height inside induced fractures. An experimental study was conducted and used to develop lab-based correlations that can predict slickwater proppant dune height as a function of certain key parameters.
A slot flow apparatus was designed and used to conduct more than 70 experiments to obtain the data necessary for the correlation development. The designed fracture slot has a rough surface and is 23.25 inches high and 0.2 inch wide. White sand was tested over a wide range of field representative values for slurry velocity and proppant size and concentration.
Power law correlations were developed for slickwater proppant dune height based on slurry velocity, proppant size, and concentration. The slurry velocity refers to the initially slurry velocity before proppant starts to settle inside the induced fracture. The overall correlation was developed by experimentally studying the effect of each parameter on the dune height and then combining them all in one correlation based on their respective relationships. The developed correlation covers proppant sizes ranging from 100 to 20/40 mesh and concentrations ranging from 0.25 to 2.80 ppg. The developed correlation showed high prediction accuracy relative to obtained lab data with an average error value of less than 0.6% relative to lab data. The developed correlation was further evaluated for its accuracy relative to lab data and the previously published correlation by Wang et al. (2003).
The developed correlation is the first of its type to be based on experimental data while using rough surface slot walls. Roughness is proven to have a considerable effect on proppant settling which makes this correlation more representative for field applications. Also, compared to the well-known correlation by Wang et al. (2003), this correlation covers a wider range of proppant sizes, concentrations, and slurry velocities.
Close Encounters in the 3rd Dimension: Using Diagnostic Fracture Injection Tests DFITs from the Alberta Duvernay Shale Formation to Quantify Simultaneous Horizontal- & Vertical-Plane Hydraulic Fracture Growth
Authors: Nicholson A. Kirby , Hawkes Robert V. , Bachman Robert C. 
Published: January 2019

Abstract
This paper will benefit engineers and geoscientists interested in creating representative hydraulic fracture simulation models and optimizing commercial-scale fracture treatments. The paper focuses on the emerging Duvernay shale formation in Alberta, Canada. Well fracturing pressures are often significantly higher than the Overburden (OB, lithostatic) pressure. Pressures above OB likely create horizontal (hz) bedding plane fracture components since sedimentary rocks are almost always weaker along bedding planes. Most fracture design simulators do not account for the simultaneous existence of multi-plane fractures (Figure 1). Therefore, scaled treatment designs for optimizing fluids, proppant schedules and production performance may be flawed. A key question is: What proportion of the overall fracture volume do horizontal-plane features take? The answer can be sought using the Pressure Transient Analysis (PTA) workflow for Diagnostic Fracture Injection Tests (DFITs) described by Bachman et al (2012, 2015) combined with simple PKN and GDK fracture models to represent the hz and vertical plane fracture components.
DFIT analysis techniques and interpretation are hotly debated topics of late. The authors believe a portion of the gap in the understanding of how hydraulic fractures behave is a result of assuming fracture components are fully, or dominantly, vertical. Analysts often interpret high fracturing pressures as tortuosity or near-well friction. However, during the fall-off period after pumping a DFIT, pressures above OB can persist for up to 20 minutes after pump shut-down. Analysis of these tests often exhibit early-time radial flow signatures which are coincident with the OB gradient of ~22kPa/m (1psi/ft) also indicative of hz plane fractures. In Nicholson et al 2017 four field DFIT examples were presented showing strong evidence of hz plane fractures in various depths and formations found in the Western Canadian Sedimentary Basin.
In the current paper DFIT PTA analysis is applied to two West Shale Basin Duvernay datasets. A physical model is presented (Figure 1) that incorporates the in-situ stress regime, rock fabric, and pore pressure and that allows history matching of DFIT leak-off and closure behavior for fractures above OB pressure. Simple calculations are provided to estimate the volume and dimensions of these same components for a small volume, single viscosity, no-proppant injection DFIT. This unique approach provides a valuable calibration point for building more advanced simulation models.
Wavelet Analysis of DFIT Data to Identify Fracture Closure Parameters
Authors: Unal Ebru , Siddiqui Fahd , Soliman Mohamed Y. , Dindoruk Birol 
Published: January 2019

Abstract
Due to the shift from conventional reservoirs towards unconventional, ultra-low permeability reservoirs in the last decade, Diagnostic Fracture Injection Test (DFIT) has become one of the dominant and economically practical pressure transient tests. It is crucial to analyze and interpret DFIT data correctly to obtain essential fracture design and reservoir parameters. This study presents the application of wavelet analysis to DFIT falloff pressure data to determine fracture closure pressure and time, to ultimately improve the overall efficiency of hydraulic fracturing designs.
In this study, DFIT pressure is treated as a non-stationary signal and analyzed by one of the signal processing techniques which is wavelet transformation. The purpose of signal analysis is to extract relevant information from a signal by transforming it. Firstly, the signal is transformed into wavelet domain by Discrete Wavelet Transformation (DWT) to calculate high-frequency wavelet coefficients (details), then change-point detection technique is applied to distinguish major changes within the coefficients trend to determine fracture closure pressure and time.
DFIT pressure decline data from different wells were analyzed by wavelet transformation. Detail coefficient demonstrates different patterns depending on the formation analyzed and near wellbore activities. This is expected because wavelet analysis is sensitive to any physical changes within the system. From the amplitude changes of the coefficients, wavelet tool demonstrates the fracture closure as a continuing process.
Because wavelet is sensitive to changes in the system, it detects the fracture closure unambiguously by amplitude change, as compared to slope changes in other conventional methodologies. A comparison with some of the most commonly used diagnostic techniques, conventional log-log diagnostic plot, square root time, G-function and its derivative analysis are also provided in this study.
There have been several publications discussing various techniques analyzing DFIT pressure decline in unconventional formations and yet there is relatively high uncertainty in before-closure-analysis. However, this methodology is more sensitive to fundamental changes in the system, so application in detecting closure pressure and time decreases the uncertainty compared to other conventional tangential methodologies.