bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrative Approach to Teaching of the Circuit Design of Analog Electron Devices in the NI ELVIS Platform
Authors: Stukach Oleg V. , Mirmanov Arman B. 
Published: August 2018

Modern graduates need to work with electronic devices. On laboratory work, students conduct experiments to solve practical problems of researching real problems that arise in the design and operation of electronic devices. However, the shortage of laboratory equipment and assistants for maintenance and assistance in work, its high cost reduce the quality of laboratory work. On the other hand, modern education is increasingly using a network resource. Virtual laboratories have their advantages, but even when carrying out a physical experiment in them, the sense of the reality of what is happening disappears. Effective solutions to the effectiveness and quality of conducting laboratory exercises can be found using a system of virtual instruments that can be accessed via the Internet or directly at the university.The aim of the research is to show, by the example of one experimental device made on the National Instruments ELVIS platform, the advantages of a combined approach to learning – a successful combination of a virtual resource and a real physical experiment. The laboratory model described in the article is very practical for studying radio-engineering devices, and it can ideologically serve as a basis for other similar developments.The research was based on the prototype board for studying the basics of analog electronics for the NI ELVIS workstation, the cycle of laboratory work on the general technical discipline “Electronics”, the results of their protection, and the results of intermediate student controls. In work the following methods are used: laboratory experiment, modeling, pedagogical testing. The results of the research show that students feel the need for more knowledge about real processes and systems. This need is most evident in the direction of the preparation of bachelors of engineering and technology. They expect from a laboratory work a real physical experiment, but with the convenience of computer-processing results. A new paradigm for studying radio electronic devices, based on physical experiments in a virtual instrument system gives an improvement in the quality of instruction and allows students to study the circuitry of analog devices more effectively. The ideology of virtual instruments leads to more motivation for students; they gain skills to work with modern measuring equipment and at the same time communication skills in a group, as the computer resource is used as a research tool, not the purpose of learning.A physical experiment, using virtual measuring instruments, accessibility and mobility of laboratory facilities, additional motivation of students are the main advantages of using the NI ELVIS hardware and software platform with a specialized breadboard model in the educational process.
Synthesis and Characterization of a Novel Ionic Liquid Based on N,N,N,N-tetramethylethylenediamine and its Application in the Synthesis of 1,8-dioxo-octahydro Xanthenes
Authors: Piralghar Zahra Abdi , Hashemi Mohammad Mahmoodi , Ezabadi Ali 
Published: August 2018

Aim and Objective:
In this work, we synthesized and characterized a novel Brönsted
acidic ionic liquid from the reaction of N, N, N’, N’-tetramethylethylenediamine with chlorosulfonic
acid and explored its catalytic activity in 1, 8-dioxo-octahydroxanthenes synthesis.

Materials and Methods:
Dimedone, aryl aldehydes, and the ionic liquid as the catalyst were reacted
under solvent-free conditions. The progressive of the reaction was monitored by a thin layer of
chromatography (ethyl acetate/n-hexane = 1/5). All products were characterized as the basis of their
spectra data and melting point by comparison with those reported in the literature.

Results:
The prepared ionic liquid was successfully applied in the synthesis of 1, 8-dioxooctahydroxanthenes
in good to high yields on the reaction of aryl aldehyde and dimedone at 120oC
under solvent-free conditions.

Conclusion:
This research demonstrates that the catalyst is impressive for 1, 8-dioxo-octahydroxanthenes
synthesis under solvent-free conditions.
Antibacterial Flavonoids Against Oral Bacteria of Enterococcus Faecalis ATCC 29212 from Sarang Semut (Myrmecodia pendans) and Its Inhibitor Activity Against Enzyme MurA
Authors: Kurnia Dikdik , Apriyanti Eti , Soraya Cut , Satari Mieke H. 
Published: August 2018

Background:
A significant number of antibiotics are known to inhibit peptidoglycan synthesis
in the cross-linking stage, while the drug fosfomycin is the only one known to inhibit MurA.
Escalated antibiotic resistance has had an impact on the efficacy of fosfomycin, thus demanding the
discovery of suitable substitutes with improved potential for MurA inhibition. The aim of this work
is to isolate antibacterial compounds from Sarang Semut (Myrmecodia pendans) and to evaluate their
antibacterial activity against pathogenic oral bacteria of Enterococcus faecalis ATCC 29212 and inhibitory
activity against MurA enzyme.

Methods:
The antibacterial compounds from Sarang Semut were isolated by a bioactivity-guided
separation method with various solvents and combination of column chromatography on normal and
reverse phases. The compounds with concentrations of 1000 and 5000 ppm were assessed against
E. faecalis ATCC 29212 by agar well diffusion method, with chlorhexidine and fosfomycin being
used as positive controls.

Results:
Two antibacterial compounds isolated from Sarang Semut were identified as two new flavonoids
derivates of 1 (10 mg) and 2 (4 mg). Both compounds were tested for antibacterial activities
against E. faecalis. MIC values of compounds 1 and 2 were 8.15 and 8.05 mm at 1000 ppm and 8.62
and 8.55 mm at 5000 ppm, respectively. MBC values were 156 and 625 ppm for 1 and 625 and 2500
ppm for 2, respectively. In an inhibitory murA enzyme activity assay, compounds 1 and 2 were
shown to inhibit the enzyme activity by IC50 values of 21.7 and 151.3 ppm.

Conclusion:
The study demonstrated that ethyl acetate fraction of Sarang Semut contained antibacterial
flavonoids as active constituents that showed activity against E. faecalis. These results showed
the plant’s potential in herbal medicine and the development of new antibacterial agent for pathogenic
dental caries.
A Brief Literature and Review of Patents on Thiazole Related Derivatives
Authors: Sharma Diksha , Bansal Kushal K. , Sharma Archana , Pathak Meenakshi , Sharma Prabodh C. 
Published: August 2018

Background:Thiazole is widely investigated bioactive scaffold and dynamic tool in medicinal chemistry research. Significance of thiazole compounds are well documented as thiazole is an obligatory structure of number of currently available therapeutics. In spite of that, thiazole derivatives are endowed with myriad biological activities, such as antiviral, anticancer, antibacterial, antifungal, antimalarial, antiparkinsonian, anti-inflammatory activities and many more.Methods:In recent past, different approaches have been introduced for synthesis of thiazole and related compounds. Intrinsic molecular interaction between newly synthesized thiazole compounds and plethora of drug targets/enzymes has rendered discovery of new drug molecules with advances in modes of action. A renewed interest in therapeutic use of thiazole derivatives has been seen among the prospective researchers as exemplified by influx of huge scientific articles and patents. Some important patents of anti-infective and anticancer interest have been addressed appropriately and are presented in tables.Results:This review paper is a contemporary approach on therapeutic/applications of thiazole derivatives by summarizing important patents filed from 2000-2017. The main focus of these patents is on anti-infective and anticancer potential of thiazole based compounds.Conclusion:These approaches may provide valuable information for the further design of more active biological agents through various modifications and derivatizations.
Cariprazine in Bipolar Depression and Mania: State of the Art
Authors: Mazza Marianna , Marano Giuseppe , Traversi Gianandrea , Carocci Valentina , Romano Benedetta , Janiri Luigi 
Published: August 2018

Background & Objective: Cariprazine is a piprazine derivative approved by the FDA in
2015 for the treatment of schizophrenia and bipolar manic or mixed episodes in adults. High affinity
for D3 dopamine receptors and observed actions on 5HT1A, 5HT2A and alpha 1B receptors differentiate
it pharmacologically from other antipsychotics. This review is a comprehensive and thorough
summary of the most important findings on cariprazine use in bipolar mania and depression. Pharmacokinetics,
pharmacogenetics, tolerability and safety adverse effects are discussed in this paper.

Results & Conclusion:
Moreover, the results from pivotal clinical trials are presented. Cariprazine represents
an additional option for clinicians to treat patients with bipolar disorder. It shows a unique pharmacological
profile and has demonstrated in randomized clinical trials efficacy and general tolerability compared
to placebo in bipolar mania and seem to be a promising therapeutic option for bipolar depression.
Bibliografie - GT 2013 nr 3
Authors: Collumbien Hugo 
Published: August 2018

“Met brieven van de wet. Stedelijk briefverkeer in het laatmiddeleeuws graafschap Vlaanderen.” MGOG
“Oud Vlaendre op de Wereldtentoonstelling van 1913 opnieuw bezocht.” Rudy Claerman
“3500 Huisnamen te Gent en elders vermeld in de Gazette van Gend(t) (1749-1800).” Georges Souffreau
Per huurbootje doorheen de stad. Vigilanten te water in 1881.
Authors: Devriese Luc 
Published: August 2018

Ooit ging het er anders aan toe. Je kon ook in het stadscentrum een bootje huren, maar dan niet om je stad te bezichtigen van op het water. Niemand dacht er aan zoiets extravagants te ondernemen, tenzij misschien een zeldzame in Gent verdwaalde excentrieke Engelsman. Je kon er wel een en ander mee vervoeren over de vele Gentse watertjes om misschien een van op straat moeilijk bereikbaar achterhuis te bevoorraden, enz. In elk geval om ‘iets nuttigs’ te doen.
Nog herkenbaar? De Iepenstraat bij de Zandpoort en de Houtlei
Authors: Devriese Luc 
Published: August 2018

We nodigen je uit om aan de hand van de hierbij gereproduceerde afbeeldingen, nieuw met oud te vergelijken aan het uiteinde van de Gebroeders Van De Veldestraat bij de Oude Houtlei, net voor de bocht naar de Annonciadenstraat straat, richting Rozemarijnbrug.
Armoedige straatjes en beluiken in de Overpoortbuurt.
Authors: Devriese Luc 
Published: August 2018

De hele zone tussen de Overpoortstraat en de Schelde achter het Kramersplein met de oude stadsschool (nu Liberaal Archief) was tot in de jaren 1970 een sjofele volksbuurt met kleine straatjes.
Lezers aan het woord. Verschenen.
Authors: Devriese Luc 
Published: August 2018

Verschenen boeken :
'Van Andriesschool tot Zondernaamstraat', Bart D’hondt
'Van Mensen & Dingen' 2014 nr. 4: publieke toiletten, detoxen, sexcinema Leopold III, militaire eretekens W.O. I en een carnavalsviering in 1884
Inventaire archéologique - fiche nr. 346. L'Escalier régence.
Authors: Devriese Luc 
Published: August 2018

Onder de titel ‘terme d’escalier régence’ stelde Armand Heins in 1904 een fiche op over een trapkolom bewaard in het Archeologisch Museum van de stad, destijds in de kapel van het Caermersklooster in het Patershol.
Huis De Baerdemaecker, Désiré Fiévéstraat nr. 34.
Authors: Van Ryssel Daniël 
Published: August 2018

De straat van Nieuwland tot het Stapelplein met het hier besproken huis werd genoemd naar Désiré Fiévé (Gent 1825-1908), houthandelaar, grondeigenaar, rechter bij de handelsrechtbank, katholiek volksvertegenwoordiger en senator. Ze werd in 1857 dwars doorheen zijn eigendom getrokken. Het straatbeeld wordt bepaald door magazijnen en opslagplaatsen (dichtbij de haven) en huizenblokken van arbeiders en kleine burgerhuizen.
Edith Cavell in Gent.
Authors: De Decker Arthur 
Published: August 2018

Op 12 oktober 1915 werd de Britse verpleegster Edith Cavell (1865-1915) te Schaarbeek gefusilleerd door een Duits vuurpeloton. Zij staat bekend als verpleegster die een humanitair ontsnappingsnetwerk voor geallieerde militairen opzette en werd daarvoor ter dood veroordeeld door de Duitse bezetter. Cavell is één van de symboolfiguren van de Eerste Wereldoorlog.
Loonboekje - Loonzakje
Authors: Rouquart Willy 
Published: August 2018

Bij de foto van een loonboekje (18,3 x 13,5 cm). De betrokkene werd wekelijks betaald (6 dagenweek) en verdiende bv. in de 3de week van 1936 (van 13 t/m 18 januari) 114,25 BEF. Achteraan is van de kaft een zakje gemaakt waarin het geld werd gestopt.
Gentse keldercafés.
Authors: Devriese Luc 
Published: August 2018

Hier en daar kan je er nog in neerdalen, iets bestellen en gezellig samen zitten, maar ooit waren er veel meer in het Gentse stadscentrum: drankgelegenheden in kelders. In straten zoals de Hoogpoort verhuurden nogal wat eigenaars de oude kelders onder hun ‘stenen’ en andere oude huizen als café, soms dancing (maar dan vooral voor slows op één enkele tegel).
Brusselsepoortstraat nr. 142. Een huis met een rijke geschiedenis
Authors: De Smet Tineke 
Published: August 2018

De aankoop in 2004 van een huis in de Brusselsepoortstraat vormde de aanleiding tot een zoektocht naar wat er achter de stenen verborgen zit. Hoe zag het er daar uit, een eeuw, meerdere eeuwen geleden?
The Fallen Angels, Jan Breidelstraat 29-31, een bouwhistorisch onderzoek
Authors: Goeminne Koen 
Published: August 2018

De woning die in deze beschrijving van een bouwhistorisch onderzoek aan bod komt, draagt het huisnummer Jan Breydelstraat 29-31 en is gebouwd op de kadasterpercelen 3062a en 3062a bis. Vandaag staat dit gebouw bekend als de The fallen Angels, een winkeltje waar men naast oude dinky toy autootjes en vintage postkaarten vooral ondergedompeld wordt in een wereld van nostalgie en curiosa,
Voor haard en land 1914-1915. Gentenaars uit de christelijke arbeidersbeweging in de grote oorlog.
Authors: Dekeyser Erik 
Published: August 2018

Een opleidingskamp te d’Auvours (Centre d’Instruction d'Infanterie n° 7) voor Belgische infanteriesoldaten bevond zich 12 km ten oosten van Le Mans. Op het einde van 1914 werd deze plaats het belangrijkste opleidingscentrum voor de infanterie van het Belgische Leger (5 à 6000 manschappen, vooral Vlamingen).
Seleksi Isolat Bakteri Amilolitik dari Rhizosfer Canna edulis, Kerr. untuk Produksi Poli Hidroksi Alkanoat dari Limbah Cair Tapioka
Authors: Nurhayati Nurhayati , Radjasa Ocky Karna , Prijambada Irfan Dwidya 
Published: August 2018

Akumulasi sampah plastik berbasis petrokimia di tempat pembuangan sampah mengganggu lingkungan karena plastik sifatnya tidak mudah didegradasi secara biologi dan sangat tahan di lingkungan. Penggantian plastik yang berasal dari bahan petrokimia dengan bahan plastik yang mudah terdegradasi secara biologi merupakan tantangan tersendiri, baik dari sisi perancangan proses maupun ketersediaan mikrobia lokal yang sesuai untuk proses tersebut. Oleh karena itu, penelitian ini dilakukan sebagai upaya untuk mendapatkan bakteri isolat lokal penghasil PHA yang mampu mengkonsumsi substrat berupa pati. Substrat pati dipilih karena ketersediaan limbat industri tapioka sebagai bahan baku potensial dan murah untuk produksi PHA. Bakteri amilolitik untuk produksi PHA telah berhasil diisolasi dari rhizosfer Canna edulis, Kerr. di Cangkringan, Sleman, Yogyakarta, Indonesia. Bakteri yang diisolasi merupakan bakteri dengan kemampuan memproduksi PHA dan memiliki kemampuan melakukan rangkaian reaksi pada limbah cair industri tapioka dan rangkaian reaksi pembentukan PHA. Telah berhasil didapatkan 10 bakteri yang memiliki aktivitas amilolitik dan dapat menghasilkan PHA menggunakan limbah cair industri tapioka. Analisis kuantitatif PHA menggunakan spektrofotometer menunjukkan bahwa isolat Bacillus sp. C8 menghasilkan PHA paling tinggi sebesar 2,095 mg/mL. Analisis hasil metabolism isolat C8 menggunakan FTIR memperlihatkan puncak spesifik 1363,67 cm-1, 1641,42 cm-1, 2929,87 cm-1, 3408,22 cm-1 adalah verifikasi adanya CH3, C=O, C-H dan OH dari PHA.
An Analysis of Contributors, Institutions, and Content of Accounting and the Public Interest 2001–2015
Authors: Roberts Diane H. 
Published: August 2018

ABSTRACT
This paper explores the contribution of the AAA Public Interest Section academic journal, Accounting and the Public Interest, to socially responsive and responsible accounting scholarship. Contributors, their doctoral-granting schools, institutional affiliation at time of publication, and their research topics in the first 15 volumes were analyzed. Source literature is explored through analysis of references. Citation analysis performed using Google Scholar's advanced search function revealed strong citation of papers published in API, both in terms of numbers of citations and quality of citing journals. Overall the study results indicate API is a high-quality publication and the journal is fulfilling its mission to provide an outlet for innovative research through use of alternative theories and methodologies.
Data Availability: Data are available from the public sources cited in the text.
FORMAÇÃO INICIAL DE PROFESSORES DE LÍNGUA INGLESA: O GLOCAL EM ARTICULAÇÕES ENTRE UNIVERSIDADE E ESCOLAS
Authors: Ramos Rosinda Castro Guerra , Fidalgo Sueli Salles , Sprenger Terezinha Maria 
Published: August 2018

No presente artigo, visamos a ilustrar como uma proposta de formação de professores busca integrar o conhecimento local globalizado e o conhecimento global localizado, conceito a que Kumaravadivelu(2006) se refere como glocal. Assim, centradas nesse objetivo, descrevemos o curso integrado de Licenciatura em Português-Inglês da Universidade Federal de São Paulo (Unifesp), enfocando especificamente a formação de professores de inglês, área em que atuamos. Primeiramente, fazemos uma exposição geral do curso em foco e de seus princípios teóricos que o alicerçam. A seguir, apresentamos as disciplinas específicas de língua e literaturas de língua inglesa para então destacarmos as que tratam especificamente da formação de professores de inglês. Finalmente analisamos excertos de relatórios de estágio para verificar o que revelam sobre a articulação entre o local e global.
In vitro effects of three equimolar concentrations of methylprednisolone acetate, triamcinolone acetonide, and isoflupredone acetate on equine articular tissue cocultures in an inflammatory environment
Authors: Trahan Richard A. , Byron Christopher R. , Dahlgren Linda A. , Pleasant R. Scott , Werre Stephen R. 
Published: August 2018

Abstract
OBJECTIVE To compare the effects of 3 equimolar concentrations of methylprednisolone acetate (MPA), triamcinolone acetonide (TA), and isoflupredone acetate (IPA) on equine articular tissue cocultures in an inflammatory environment.
SAMPLE Synovial and osteochondral explants from the femoropatellar joints of 6 equine cadavers (age, 2 to 11 years) without evidence of musculoskeletal disease.
PROCEDURES From each cadaver, synovial and osteochondral explants were harvested from 1 femoropatellar joint to create cocultures. Cocultures were incubated for 96 hours with (positive control) or without (negative control) interleukin (IL)-1β (10 ng/mL) or with IL-1β and MPA, TA, or IPA at a concentration of 10−4, 10−7, or 10−10M. Culture medium samples were collected from each coculture after 48 and 96 hours of incubation. Concentrations of prostaglandin E2, matrix metalloproteinase-13, lactate dehydrogenase, and glycosaminoglycan were determined and compared among treatments at each time.
RESULTS In general, low concentrations (10−7 and 10−10M) of MPA, TA, and IPA mitigated the inflammatory and catabolic (as determined by prostaglandin E2 and matrix metalloproteinase-13 quantification, respectively) effects of IL-1β in cocultures to a greater extent than the high (10−4M) concentration. Mean culture medium lactate dehydrogenase concentration for the 10−4M IPA treatment was significantly greater than that for the positive control at both times, which was suggestive of cytotoxicosis. Mean culture medium glycosaminoglycan concentration did not differ significantly.
CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that the in vitro effects of IPA and MPA were similar to those of TA at clinically relevant concentrations (10−7 and 10−10M).
Prognostic value of CD44 variant isoform expression in dogs with multicentric high-grade B-cell lymphoma
Authors: Motegi Tomoki , Tomiyasu Hirotaka , Goto-Koshino Yuko , Takahashi Masashi , Hiyoshi-Kanemoto Saaya , Fujino Yasuhito , Ohno Koichi , Tsuimoto Hajime 
Published: August 2018

Abstract
OBJECTIVE To determine the prognostic value of CD44 variant isoform expression in dogs with multicentric high-grade B-cell lymphoma (BCL).
ANIMALS 45 dogs with multicentric BCL and 10 healthy control Beagles.
PROCEDURES The medical record database of a veterinary teaching hospital was searched to identify dogs with BCL that were treated between November 2005 and April 2015. Information regarding overall response to chemotherapy, progression-free survival (PFS) time, and overall survival time was extracted from each record. Archived lymph node aspirate specimens from dogs with BCL and lymph node aspirate specimens from the 10 control dogs underwent real-time PCR analysis to determine mRNA expression of CD44 variant isoforms of exons 3, 6, and 7 and the CD44 whole isoform. For each isoform, mRNA expression was compared between dogs with BCL and control dogs. The mean relative expression of each isoform was used to classify dogs with BCL into either a high- or low-expression group, and overall response rate, PFS time, and overall survival time (ie, indices of prognosis) were compared between the 2 groups.
RESULTS For all isoforms evaluated, mean relative mRNA expression for dogs with BCL was numerically lower than that for control dogs. Dogs with BCL and high CD44 isoform expression had a lower overall response rate, median PFS time, and median overall survival time, compared with dogs with BCL and low CD44 isoform expression.
CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that, for dogs with BCL, high expression of exons 3, 6, and 7 was associated with a poor prognosis.
Genetic diversity and stand structure of neighboring white willow (Salix alba L.) populations along fragmented riparian corridors: a case study
Authors: Sitzia T. , Barcaccia G. , Lucchin M. 
Published: August 2018

Abstract
Remnant riparian woodlands have an important landscape function, due to their ability to act as ecological corridors. In this study we used molecular markers to assess the genetic variation occurring within and between spontaneous white willow (Salix alba L.) riparian woodlands. Our main goal was to evaluate the extent to which the fragmentation of a woodland corridor along a heavily impacted river in northeastern Italy and stand structural conditions may have affected the population genetics. Although having different structures, the three examined white willow stands showed high estimates of genetic similarity, as well as low genetic differentiation between them, indicating that they shared a similar gene pool and that the stands could result from a common set of individual genotypes, and should be regarded as metapopulations. The magnitude of genetic diversity within each of the stands and genetic differentiation between them, despite their high sexual reproductive capacity associated with a highly marked gene flow, suggest that these stands are dynamic and capable of adaptive responses to possible changes in their fluvial environment. However, the factors influencing genetic diversity should be interpreted from a long-term perspective. Fluvial geomorphic patterns in regulated rivers may be modified to a degree that could lead to changes in dispersal processes, sexu­al reproduction vs. asexual propagation, and hence genetic diversity.