bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visualization of Cartilage from Knee Joint Magnetic Resonance Images and Quantitative Assessment to Study the Effect of Age, Gender and Body Mass Index (BMI) in Progressive Osteoarthritis (OA)
Authors: Matada Mallikarjunaswamy Shivagangadharaiah , Holi Mallikarjun Sayabanna , Raman Rajesh , Jayaramu Suvarna Sujana Theja 
Published: October 2018

Background:
Osteoarthritis (OA) is a degenerative disease of joint cartilage affecting
the elderly people around the world. Visualization and quantification of cartilage is very much essential
for the assessment of OA and rehabilitation of the affected people. Magnetic Resonance Imaging
(MRI) is the most widely used imaging modality in the treatment of knee joint diseases. But
there are many challenges in proper visualization and quantification of articular cartilage using
MRI. Volume rendering and 3D visualization can provide an overview of anatomy and disease
condition of knee joint. In this work, cartilage is segmented from knee joint MRI, visualized in 3D
using Volume of Interest (VOI) approach.

Methods:
Visualization of cartilage helps in the assessment of cartilage degradation in diseased
knee joints. Cartilage thickness and volume were quantified using image processing techniques in
OA affected knee joints. Statistical analysis is carried out on processed data set consisting of 110
of knee joints which include male (56) and female (54) of normal (22) and different stages of OA
(88). The differences in thickness and volume of cartilage were observed in cartilage in groups
based on age, gender and BMI in normal and progressive OA knee joints.

Results:
The results show that size and volume of cartilage are found to be significantly low in OA
as compared to normal knee joints. The cartilage thickness and volume is significantly low for
people with age 50 years and above and Body Mass Index (BMI) equal and greater than 25. Cartilage
volume correlates with the progression of the disease and can be used for the evaluation of the
response to therapies.

Conclusion:
The developed methods can be used as helping tool in the assessment of cartilage
degradation in OA affected knee joint patients and treatment planning.
Content Analysis, Cytotoxic, and Anti-metastasis Potential of Bioactive Polysaccharides from Green Alga Codium intricatum Okamura
Authors: Vasquez Ross D. , Lirio Stephen 
Published: October 2018

Background:
Codium intricatum, locally known as Pukpuklo, is a seasonal and edible green
alga found in Ilocos Norte, Philippines. In this study, the biochemical content, cytotoxic and inhibitory
potential against Matrix Metalloproteinase-1 (MMP-1) production of the polysaccharide-protein fractions
from C. intricatum is first reported. MMPs are novel targets for therapeutic intervention with the
potential to inhibit tumor growth, metastasis and invasion either on their own or in conjunction with
cytotoxic treatments.

Methods:
Water-soluble Crude Polysaccharide (CP) and its fractions (CFs) from C. intricatum were
isolated using hot water and ion-exchange chromatography and analyzed using different analytical techniques.
Cytotoxicity against MCF-7 breast cancer cells and Human normal Dermal Fibroblasts (HnDFs)
was determined by MTT assay. The MMP-1 inhibitory potential was tested in UVB exposed Human
normal Dermal Fibroblast Cells.

Results:
CP and CFs afforded carbohydrates (2.07-16.1%), sulfates (1.81%- 9.9%), protein (0.05-2.7%),
ash (<77.2%), lipids (<1.0%) and uronic acid (0.15- 4.49%). FT- IR and NMR spectra of CP and CFs
exhibited absorption peaks comparable to sulfated galactans. Both CP and CFs significantly inhibited
the growth of breast cancer (MCF-7) in a concentration-dependent manner (p<0.05), induced proliferation
of HnDFs, inhibited the production of Matrix metalloproteinase-1 (MMP-1) in UV-B induced
HnDFs (p<0.05).

Conclusion:
Results are highly suggestive that polysaccharide fractions from C. intricatum are bioactive
molecules with cytotoxic and anti-metastasis potential.
Antispermatogenic Effect of Piper betel Leaf Stalk Extract with Reference to Kinetic Studies of 17β-hydroxy Steroid Dehydrogenase Enzyme in Testes of Albino Rats
Authors: Amgoth Govardhan Naik , Venkataramanaiah P. , Challa Changamma 
Published: October 2018

Background:
In the development and maintenance of male reproductive function and fertility,
steroidogenesis plays a key role.

Aims:
The aim of the present study was to investigate the effect of the betel leaf stalk extract on 17β-
hydroxy steroid dehydrogenase activity levels.

Methods:
The observed elevation in testicular cholesterol levels may be due to decreased androgen
production, which resulted in impaired spermatogenesis. The decreased steroidogenic enzyme 17β-
HSD activity represents decreased androgen production by the extract administration. Reduction in
enzyme active site density and Km value revealed that there was a reduction in enzyme-substrate affinities
and rate of E-S complex breakdown in the administered rat testes.

Results & Conclusion:
The administration of betel leaf stalk extract resulted in decreased enzyme
content probably through impaired synthesis.
α-Glucosidase and α-Amylase Inhibitory Effect and Antioxidant Activity of Aerial Part from Linaria aegyptiaca L.
Authors: Bekhaoua Abir , Khacheba Ihcen , Boussoussa Hadjer , Yousfi Mohamed 
Published: October 2018

Background:The genus Linaria belongs to the Scrophulariaceae family. It is a large genus comprising about 200 species. Various parts of several Linaria species have been reported to exhibit various biological effects. In Algeria especially in the Sahara and steppe regions, the different species of Linaria have several uses in dietary application.Objective:The aims of this study are to evaluate the α-Glucosidase and α-Amylase inhibitory effects and the antioxidant activity using in vitro assays by an organic extract of the aerial part of Linaria aegyptiaca collected in two months, April and June, from southern Algeria.Methods:The extracts were obtained with successful maceration in (hexane, dichloromethane, acetone and methanol). The phenolics and flavonoids contents of L. aegyptiaca extracts were evaluated with Folin- Ciocalteu and aluminum chloride reagents, respectively. Then, we studied their inhibitory effects on α-Glucosidase and α-Amylase enzymes. The antioxidant potential was determined in vitro with DPPH, ABT and Phosphomolybdate tests.Results:The highest phenolic and flavonoid content were detected in the methanolic extracts of Linaria aegyptiaca collected in April. All the extracts showed good inhibitory activity on both enzymes, where the best activity was against α- amylase by acetonic extract collected in June with an IC50 = 95.03 μg/ml. The evaluation of antioxidant activity showed that all the extracts exhibited a good antioxidant capacity compared to standard antioxidants.Conclusion:The aim of this research is to establish the anti-diabetic properties and the probable alpha glucosidase and alpha amylase inhibitory activities of Algerian Linaria aegyptiaca species. These results show that this species has good antioxidant properties and a good potential for hyperglycemia management, too. The Algerian Linaria aegyptiaca can be considered as a natural source of anti-hyperglycemic treatment and might be interesting for the prospect of new molecules with antidiabetic effect.
Performance Analysis of QMF Filter Bank For Wireless Voip in Pervasive Environment
Authors: Luhach Ravindra , Jha Chandra K. , Luhach Ashish K. 
Published: October 2018

Background:
Voice over Internet Protocol (VoIP) has emerged as one of the most significant
technology in the field of communication and evolved as a substitute to the conventional communication
method as the Public Switched Telephone Network (PSTN). Along with the advantages such
as scalability and security, VoIP has some threats such as voice quality and interference that must be
dealt with. The voice quality in VoIP is degraded when transmitted over a computer network due to delay,
jitter and packet loss etc. Packet loss is one of major reasons for the signal quality degradation.

Objective:
In this research article, Quadrature Mirror Filter Bank (QMF) has been implemented in
wireless VoIP system to enhance the quality of the signals transmitted.

Results:
The performance has been evaluated under varying network conditions of packet loss.

Conclusion:
Significant improvement has been observed in the quality of VoIP signal.
Temporal Pattern Specifications for Self-Adaptive Requirements
Authors: Yahiaoui Ayoub , Bendjenna Hakim , Roose Philippe , Chung Lawrence , Amroune Mohamed 
Published: October 2018

Background:
Systems whose requirements change at a rate that necessitates adaptation
without human intervention are called self-adaptive systems, and they have the ability to adjust their
behavior autonomously at run-time in response to their environment’s evolution. Samples of applications
that require self-adaptation include Smart home systems and environmental monitoring.
However, self-adaptivity is often constructed in an ad-hoc manner.

Methods:
In this paper, the authors present a pattern-based specification language for self-adaptive systems.
Its semantics are presented in terms of fuzzy logic. Thus, enabling a meticulous processing of requirements,
in order to permit the formulation of self-adaptive requirements accurately, thereby facilitates
the design of systems that are flexible and responsive to adaptation in a systematic manner.

Results:
To show the applicability and effectiveness of our language, the authors apply it to two
case studies. One case study reviews the Smart fridge in ambient assisted living and the second case
study is focused on an ambulance dispatching system using a developed support tool.
Unit Template Based Control of PV-DSTATCOM
Authors: Varshney Gunjan , Chauhan Durg S. , Dave Madhukar P. , Nitin  
Published: October 2018

Background:
In modern electrical power distribution systems, Power Quality has become
an important concern due to the escalating use of automatic, microprocessor and microcontroller
based end user applications.

Methods:
In this paper, power quality improvement has done using Photovoltaic based Distribution
Static Compensator (PV-DSTATCOM). Complete simulation modelling and control of Photovoltaic
based Distribution Static Compensator have been provided in the presented paper. In this configuration,
DSTATCOM is fed by solar photovoltaic array and PV module is also helpful to maintain the DC
link voltage. The switching of PV-STATCOM is controlled by Unit template based control theory.

Results:
The performance of PV-DSTATCOM has been evaluated for Unity Power Factor (UPF)
and AC Voltage Control (ACVC) modes. Here, for studying the power quality issues three-phase
distribution system is considered and results have been verified through simulation based on
MATLAB software.

Conclusion:
Different power quality issues and their improvement are studied and presented here
for harmonic reduction, DC voltage regulation and power factor correction.
Нитевидные нанокристаллы на основе фосфидных соединений, полученные методом молекулярно-пучковой эпитаксии на поверхности кремния
Authors: Цырлин Г.Э. , Резник Р.Р. , Самсоненко Ю.Б. , Хребтов А.И. , Котляр К.П. , Илькив И.В. , Сошников И.П. , Кириленко Д.А. , Крыжановская Н.В. 
Published: October 2018

AbstractData on the growth and physical properties of nanostructures of the type “InAsP insert embedded in InP nanowire (NW)” grown on Si (111) surfaces by Au-assisted molecular-beam epitaxy are presented. It is found that nearly 100%-coherent NWs can be grown with a widely varying surface density. A relationship between the optical and structural properties of the NWs is revealed. It is shown that the NWs under study are formed of a purely wurtzite phase. The suggested technology opens up new opportunities for the integration of direct-gap III–V materials and silicon.
Особенности нелинейного СВЧ-отклика многозонных сверхпроводников на основе ферроселенида натрия-калия (Na-=SUB=-0.3-=/SUB=-K-=SUB=-0.7-=/SUB=-)-=SUB=-x-=/SUB=-Fe-=SUB=-2-y-=/SUB=-Se-=SUB=-2-=/SUB=-
Authors: Пестов Е.Е. , Ноздрин Ю.Н. , Елькина А.И. , Ерин Ю.C. , Лю М. , Болталин А.И. , Морозов И.В. 
Published: October 2018

Abstract —Temperature dependences of the third-harmonic power for the (Na_0.3K_0.7)_ x Fe_2 – _ y Se_2 sodium–potassium ferroselenide single crystals have been investigated by nonlinear near-field microwave microscopy. The temperature dependence of magnetic susceptibility at a frequency of 100 kHz for this compound has been measured. The experimental results suggest a double-gap structure of the (Na_0.3K_0.7)_ x Fe_2 – _ y Se_2 superconductor.
Магнитооптические свойства висмутзамещенных пленок ферритов-гранатов в сильных импульсных магнитных полях
Authors: Кудасов Ю.Б. , Логунов М.В. , Козабаранов Р.В. , Макаров И.В. , Платонов В.В. , Сурдин О.М. , Маслов Д.А. , Коршунов А.С. , Попов E.Я. , Светлов А.С. 
Published: October 2018

Abstract —A technique of measuring the rotation of the light polarization plane in pulsed magnetic fields with strength up to 40 T with a sensitivity of 0.1° is proposed. The Faraday effect has been studied in films of diluted ferrites—garnets (Lu,Bi)_3(Fe,Ga,Al)_5O_12 in the temperature range from room temperature to 78 K, including the vicinity of the magnetic moment compensation temperature. The transition to the noncollinear phase in the magnetic phase diagram is shown to occur at a magnetic field strength higher than 30 T at room temperature, and the threshold transition field tends to zero when approaching the magnetic moment compensation temperature.
Температурная зависимость параметра решетки порошков Cu-=SUB=-2-x-=/SUB=-Se (0.03&le; x&le;0.23), полученных методом механохимического синтеза
Authors: Иванов А.А. , Тарасова И.В. , Бублик В.Т. , Акчурин Р.Х. , Щетинин И.В. , Табачкова Н.Ю. , Пшенай-Северин Д.А. , Освенский В.Б. 
Published: October 2018

Abstract —The Cu_2 – _ x Se (0.03 ≤ x ≤ 0.23) powders fabricated by mechanochemical synthesis have been studied by X-ray diffraction. The in situ study has been carried out for the temperature dependences of the lattice parameters, the structures, and the phase compositions of the powders in the temperature range 25–350°C. The powder compositions are shown to differ from the charge compositions and are shifted to lower copper concentrations. The estimation of peak half-widths of the cubic β phase indicates an increase in the structure imperfection after the phase transition from the α phase to the β phase of Cu_2 – _ x Se at ~140°C. It is shown that the superpositions of the subtraction solutions (copper vacancies) and interstitials solutions (copper atoms in interstitial sites), whose proportion is changed as a function of temperature and the deviation from stoichiometry, are in the thermodynamic equilibrium in the copper selenide solid solution at room temperature. The change in the slope of the dependence of the lattice parameter of the powder Cu_2 – _ x Se samples on the composition (0.03 ≤ x ≤ 0.23) in the temperature range 25–350°C enables the suggestion that interstitial copper atom concentration increases with temperature and deviation from stoichiometry.
FATORES ASSOCIADOS À OCORRÊNCIA DO PARTO CESÁREO EM UM HOSPITAL PÚBLICO DA BAHIA
Authors: Souza Cinoelia Leal de , Mamédio Leide Jane Ferreira , Brito Mônica Farias , Silva Vandeilton Damião Oliveira da , Oliveira Kelly Albuquerque de , Santos da Silva Elaine 
Published: October 2018

A escolha do tipo de parto está diretamente relacionada aos indicadores de qualidade de saúde materno-infantil positivos e, na atualidade, observa-se que o número de parto cirúrgico tem aumentado. Com isso, este estudo objetivou analisar os fatores associados à ocorrência do parto cesáreo em um hospital público, no ano de 2014. Trata-se pesquisa quantitativa de corte transversal, com amostra probabilística de 263 partos realizados no Hospital Regional de Guanambi, Bahia. Os resultados indicaram que, no modelo de investigação, os fatores associados à ocorrência do parto cesáreo foram o índice de Apgar, com associação negativa e o parto prematuro; o sexo masculino; a raça negra e apresentação não cefálica apresentaram associação positiva. Após ajuste, mantiveram-se no modelo à raça negra, a apresentação não cefálica, o sexo masculino e a prematuridade como fatores associados à ocorrência do parto prematuro. Concluiu-se, diante da importância do ciclo gravídico-puerperal para a saúde da mulher e indicadores de saúde populacional, que é necessário estudar junto aos profissionais de saúde quais são os fatores que são associados à ocorrência de partos cesáreos nos serviços de saúde pública, buscando identificar questões que possam diminuir o número de cesariana desnecessária e as complicações decorrentes desse processo.
Palavras-chave: Cesárea. Parto normal. Parto humanizado. Saúde da mulher.
QUALIDADE DE VIDA EM IDOSOS DIABÉTICOS ASSISTIDOS NA ESTRATÉGIA DE SAÚDE DA FAMÍLIA
Authors: Duarte Emília Natali Cruz , Marques Ana Paula de Oliveira , Leal Márcia Carrera Campos 
Published: October 2018

No Brasil, os idosos apresentam mais de uma doença crônica, destacando-se o Diabetes Mellitus, entre as cinco principais patologias que afetam essa população. O objetivo deste estudo é analisar a qualidade de vida em idosos diabéticos assistidos na Estratégia Saúde da Família. Trata-se de um estudo epidemiológico, descritivo, de corte transversal realizado no município de Recife, Pernambuco, Brasil. Utilizou-se o instrumento Medical Outcomes Study Short-Form-36 para avaliar a qualidade de vida. Os dados foram coletados por meio de entrevistas domiciliares e consultas aos prontuários disponíveis nas unidades básicas de saúde, no período de julho a novembro de 2012, e analisados pelo programa Statistical Package for Social Sciences for Windows, versão 14.0. Participaram do estudo 202 idosos. Os resultados apontaram que a maioria dos idosos era aposentada e possuía rendimento entre um e dois salários mínimos, prevalecendo mulheres idosas, idosos jovens, e com baixa escolaridade. Observou-se piores escores de qualidade de vida (estatisticamente significante) nas idosas e naqueles que não executavam prática de atividade física. Concluiu-se que a qualidade de vida de idosos diabéticos assistidos na Estratégia Saúde da Família apresentou escores baixos para a Qualidade de vida.
Palavras-chave: Qualidade de vida. Saúde do idoso. Diabetes mellitus. Saúde da mulher. Envelhecimento.
ESTRATÉGIA SAÚDE DA FAMÍLIA E MORBIMORTALIDADE POR DOENÇAS CRÔNICAS EVITÁVEIS EM PEQUENOS MUNICÍPIOS
Authors: Gotler Medeiros Cássia Regina , Espindola Koetz Lydia Christmann , Quevedo Grave Magali Teresinha , Raupp Luciane Marques , Salvadori Morgana , Freitag Ana Luísa 
Published: October 2018

As Doenças Crônicas Não Transmissíveis configuram-se como a principal causa de morte no mundo, especialmente em regiões menos desenvolvidas. O objetivo do trabalho foi investigar o perfil epidemiológico das doenças crônicas não transmissíveis nos municípios que integram a 16ª Coordenadoria Regional de Saúde, no Rio Grande do Sul, dentre as que constam na Lista Brasileira de Mortes Evitáveis por Intervenções do Sistema Único de Saúde, e relacionar com a cobertura da Estratégia Saúde da Família. Trata-se de um estudo ecológico retrospectivo das doenças crônicas não transmissíveis evitáveis e das internações por condições crônicas consideradas sensíveis à atenção primária, correlacionando os óbitos e as internações com a cobertura da Estratégia de Saúde da Família na região, no período de 2001 a 2010, na população de 20 a 74 anos. Os resultados indicaram que os óbitos evitáveis por doenças crônicas não transmissíveis representaram 41,30% entre os óbitos por todas as causas. Em ordem de prevalência, destacaram-se as neoplasias malignas (17,38%), a doença isquêmica do coração (10,59%), a hemorragia intracerebral (4,30%), o diabetes mellitus (3,79%), a doença hipertensiva (2,15%), a insuficiência cardíaca (1,93%), doenças pulmonares obstrutivas crônicas (0,94%) e a aterosclerose (0,21%). As internações reduziram 49,32% e os óbitos 28,56%, apresentando correlação inversa com a cobertura de Estratégia Saúde da Família. Observou-se impacto positivo do aumento da cobertura da Estratégia Saúde da Família na redução da morbimortalidade evitável por doenças crônicas não transmissíveis. Concluiu-se que devido à região ser composta por pequenos municípios, onde a atenção básica é a principal ou única oferta de serviço de saúde no território, há a necessidade de organização de uma rede de atenção às pessoas com doenças crônicas na Região de Saúde.
Palavras-chave: Políticas públicas de saúde. Assistência à saúde. Avaliação em saúde. Doenças crônicas.
CUIDADO DO AGENTE COMUNITÁRIO DE SAÚDE JUNTO À POPULAÇÃO MASCULINA
Authors: Leite Rebeca Valentim , Pereira Ana Paula Chancharulo de Morais 
Published: October 2018

O trabalho do Agente Comunitário de Saúde para a vinculação e acompanhamento dos usuários pelas Equipes de Saúde da Família é primordial para o funcionamento dessa estratégia da Atenção Básica, necessitando a população masculina ser notada, devido à baixa frequência neste nível de atenção. Este estudo tem como objetivo compreender a percepção e as práticas dos Agentes Comunitários de Saúde junto à população masculina. Trata-se de estudo de caso, de abordagem qualitativa, do tipo descritivo-exploratório, realizado com Agentes Comunitários de Saúde de quatro Equipes de Saúde da Família de um município da Região Metropolitana de Salvador, Bahia, Brasil. A coleta de dados foi feita por meio de questionário semiestruturado e para a análise dos dados utilizou-se a técnica de Análise de Conteúdo. Os resultados apontaram quatro categorias analíticas: Ser Homem na Perspectiva dos Agentes Comunitários de Saúde; O Trabalho do Agente Comunitário de Saúde e os Homens; Barreiras do Trabalho do Agente Comunitário de Saúde com os Homens; e Visão dos Agentes Comunitários de Saúde sobre a Promoção do Acesso Masculino em seu Trabalho. Concluiu-se que os Agentes Comunitários de Saúde utilizaram questões de gênero para explicar o comportamento masculino diante de sua saúde e justificar as facilidades e os limites em seu trabalho direcionado a essa população, assim como realizavam atividades que não correspondiam às suas atribuições.
Palavras-chave: Saúde do homem. Trabalho. Agentes comunitários de saúde. Estratégia Saúde da Família.